PharMolix/UniProtQA huggingface dataset:
Protein: BETB_YERPS
Sequence: MSRYGLQKLYINGAYTDSTSGDTFDAVNPANGECIAQLQAANAQDVDKAVAAAKQGQPVWAAMTAMERSRILRRAVDILRDRNDELAAIETADTGKPLSETRSVDIVTGADVLEYYAGLIPALEGQQIPLRGSAFVYTRREPLGVVAGIGAWNYPLQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAGIYTEAGLPAGVFNVLTGSGDQVGQMLTEHPGIAKVSFTGGIASGKKVMANAAGSTLKDVTMELGGKSPLIIFADADLDKAADIAMMANFYSSGQVCTNGTRVFVPLALQAAFEQKIVERVKRIHIGDPSDERTNFGPLVSFQHRDSVMRYIDSGKREGATLLIGGYSLTEGALAHGAYVAPTVFTHCRDDMQIVREEIFGPVMSILSYQSEEEVIRRANDTEYGLAAGVVTQDLNRAHRVIHQLQAGICWINTWGESAPEMPVGGYKHSGVGRENGISTLEHYTQIKSIQVELSSFNSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: MNME_LACPL
Sequence: MPTTTEFDTIAAISTPPGEGGISIIRISGDQTFNVVTQIFKGKDLSRVQSHTINYGHIVDPDTHQEVDEVMATVMRAPKTYTREDVVEINCHGGLVATNEILQLILSHGARMAEPGEFTKRAFLNGRLDLSQAEAVMDLIRAKTDKSMKVALNQLDGDLSKLIRHLRQDILDVLAQVEVNIDYPEYDAVETMTTKMLKEKATEVAQSINQLLATAKQGKVLREGLATAIIGRPNVGKSSLLNHLLHEDKAIVTDVAGTTRDVIEEYVNVRGVPLKLVDTAGIRDTEDKVEKIGVERSRKAIGAADLVLLVLDNSQPLTAEDRELLQETDQSKRIVILNKTDLPARLDQAELAQLVDLSDVLSMSVLEQSGVTQLEQRIAKMFFNEGIESSQNNVMVTNARHIGLLNQAKQALQDVQTGLAAGMPVDLVQIDMTRCWEFLGQITGDSYEDELLDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_STRA1
Sequence: MTKQKIAVLGPGSWGTALAQVLNDNGHEVRLWGNVVEQIEEINTNHTNQRYFKDITLDSKIKAYTNLEEAINNVDSILFVVPTKVTRLVAKQVANLLKHKVVIMHASKGLEPGTHERLSTILEEEISEQYRSDIVVVSGPSHAEEAIVRDITLITAASKDIEAAKYVQKLFSNHYFRLYTNTDVVGVETAGALKNIIAVGAGALHGLGYGDNAKAAIITRGLAEITRLGVQLGADPLTFSGLSGVGDLIVTGTSVHSRNWRAGDALGRGEKLEDIEKNMGMVIEGISTTKVAYEIAQNLNVYMPITEAIYKSIYEGANIKDSILDMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRX2_XENLA
Sequence: MSYPQGYLYQPPGSLALYSCPAYGASALAAPRSEELARSSSGSAFSPYPGSAAFSAQAATGFSSPLQYSSDPTGFPSYMGSPYDAHAAGMTGALSYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSDDEDDDEGDGERVKEEQSEKAQDSNETSAEDEGISLHVDSLTDHSCSADSDGEKLPCRAADHLCESGSESKEKYEDEEDDGDEEDRVLPVKPATSSPLTGVEAPILNRQQEGSPRNSNKTNLDNGMSSSSQTPASKPKLWSLAEIATSDHKHPNLGSVLSSATSSSAAHNPSYPSSSLLGRHIYYTSPFYSNYTNYGNFNALQSQGILRYSSTAMTANEGLNQTVLSTSSMHKHTSDSVRTASNQLDQHYRPTNYESKKDPSEVCTVGVQPYP
What is the function of this protein?
Acts partially redundantly with other irx members in neural patterning.  Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord.  Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state.  Also up-regulates repressors that prevent neuronal differentiation.  Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes.  Probably dispensable for pronephric kidney development.
What are the official names of this protein?
Iroquois-class homeodomain protein irx-2, Irx2-A, Iroquois homeobox protein 2, Xiro2.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2160_PYRAE
Sequence: MQIKWFGHAAFMVEVGGARLLIDPWISNPLSPATPQDVINARPTHIMITHDHFDHMGEAVDIAKATKAPIVGTFELTLEVAEKGIPEAQTMPMNIGGTIKLGDGIELYMTPALHTANRGAPSGFVIATPEGTVYHAGDTALFRDMELIGELYDIDVALLPIGSVFTMGPREAAIATQLLRARRVVPMHYNTFPLIKQDPEDFKARVEAVSRAKVFVMKPGDVLKV
What are the official names of this protein?
UPF0173 metal-dependent hydrolase PAE2160.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: LDHC_VULVU
Sequence: MSTVKEKLIENLIEEDKISQRKITIVGTGAVGMACAICILLKDLADELALVDVAVDKLKGEMMDLQHGSLFFNTSKITSGKDYSVSANSKLVIVTAGARQQEGESRLALVQRNVNIMKSIIPAVVQHSPDCKMLIVSNPVDILTYVVWKLSGLPATRVFGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDADKDQWKNIHKQVVESAYEIIKLKGYTSWAIGLSVTDLVGSVLKNLRRVHPVSTMVKGLYGIKEEIFLSIPCVLGQNGVSDIVKINLNSDEEALFKKSADTLWNVQKELVF
What is the function of this protein?
Possible role in sperm motility.
What are the official names of this protein?
L-lactate dehydrogenase C chain, LDH-C, LDH testis subunit, LDH-X.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXG1A_SCOMO
Sequence: MNLFLVLFVFSFSVSQFFAVEAGGRKHKHQEVCIGSDGKGHQLNQFWYDNGNCRRFYCYKDEDGLVIEQTTNCELAVAENDCRIKPGKAGRYPDCCPSVECPQESKAS
What are the official names of this protein?
U-scoloptoxin(16)-Sm1a, U-SLPTX(16)-Sm1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_BORHD
Sequence: MGNNPSALKRARQNLKRNLRNVSVKSELKTIEKRCMSLIREGKKEEALEFFKFVSKKLDTAARKRIIHRNKAARKKSNLSILLLR
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: AHPF_PSEPU
Sequence: MLDATLKSQLKTYLERVTQPIEIVASLDDGAKSRELHDLLVEIASLSNLITFSADGTDARRPSFSLNRPGADISLRFAGIPMGHEFTSLVLALLQVGGHPSKASAEVIEQIQALEGEFNFETYFSLSCQNCPDVVQALNLMAVLNPNVRHVAIDGALFQDEVESRKIMAVPSIYLNGEVFGQGRMGLEEILGKIDTNAGARQAEKINAKEAFDVLVVGGGPAGAAAAIYAARKGIRTGVAAERFGGQVLDTLAIENFISVQETEGPKLATALEEHVKQYDVDIMNLQRGEALIPAAEGGLHEVRLAGGASLKAKTVILATGARWREMNVPGEQEYRGRGVAYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVAQVTLIEFDSQLRADAVLQRKLRSLPNVNVITSALTTEVLGNGEKVTGLRYKDRSTDEQHEVALEGIFVQIGLLPNTDWLKGTVELSPRGEIIVDAKGQTSIPGVFAAGDVTTVPYKQIVIAVGEGAKASLAAFDHLIRTSAPA
What is the function of this protein?
Serves to protect the cell against DNA damage by alkyl hydroperoxides.  It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.
What are the official names of this protein?
Alkyl hydroperoxide reductase subunit F.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: SC241_NAUCC
Sequence: MSHKKRVYPTAQLQYGQTNIYEQHGVPQDAGAPQGQPLQSDIPYMNAQPGVIPGQGAPMMMDNGAMPQQQMFTPAQQQLNQQIDQTTAAMGNMQFNPAANESNMYYQQPLPQQQQQQQQQQGPAKPPKPMNQLYPIDLLVAFPPPISDLSLPPPPILFPLDTIPVPSEDALAPSNYIRSTLNAVPKSNSLLKKTKLPFSLVITPYQHLHDDINPPPLNEDGTIVRCRRCRSYMNPFVHFNQDGRRWKCNICNLFNEVPSFLDRMPNDTMSNRYMRNELRYSVVEYLAPKEYSLRQPPPSTYTFIIDVSQNAMKNGLLGTTTRTLLDNLDSLPNHDGRTRISILCVDNGLHYFAIPSDDQEGQQVEMMDVCDLDDAFIPRPDSMVVNLVQCRNNIETLLTKIPQIFQNNIINKFALGPALQAAYNLTRNEGGKIIVVSATLPNIGVGQLKKRVEEANVGTPKESQQLLTCQDPFYKTFTIQCNKVQISIDMFLASEEYMDVATLANLGHFSGGQTHFYPGFSAQRITDATKFSMEFAKHLSMDTSNEVVMRARGSTGIRTTGFHGHFFNRSSDLCAFSIMNRDQSYVFDITLDENIAAEYCYVQVAILLSLNTSQRRIRVITLALPTTDSIAEVYASVDQLAVTAAFTQKAIDKAQDTSLEEARRFINQSVEDVLTTYKKELVVQNTGAGGMPLRLCANMKIFPLLMHALTKNLAFRPGRVPSDHRAAALNYMESVPLKYLLKCIYPTIYSLHDMPDEVGLPDENNEIILPEPINASYSSFETYGLYLIDNGIDLFLWMGGEALPQLVEDAFGVPNILEMPIGKQEVPVVPESPFNERIRNIINRLRNHDDVITYQSLYILRSASNSDPVQANAKELSSLRMWASTHLVEDKIMGSEGYRDFLQMMKNKTSK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24-1.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUDB_ECO57
Sequence: MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA
What is the function of this protein?
Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate.  Required for efficient folate biosynthesis.  Can also hydrolyze nucleoside triphosphates with a preference for dATP.
What are the official names of this protein?
Dihydroneopterin triphosphate diphosphatase, Dihydroneopterin triphosphate pyrophosphatase, dATP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RL1_STAAB
Sequence: MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTMGPGVKIDTASFK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CUPIN_RHORT
Sequence: MSDSNDDRPFRPFQSQYRWPGVDLLAYKEEGSAPFRSVTRQVLFSGNGLTGELRYFEVGPGGHSTLERHQHAHGVMILKGRGHAMVGRAVSAVAPYDLVTIPGWSWHQFRAPADEALGFLCMVNAERDKPQLPTEADLAMLRADDAVAAFLDGLAG
What is the function of this protein?
Catalyzes the formation of S-(methylsulfanyl)glutathione and 1-deoxy-D-xylulose 5-phosphate (DXP) from 1-methylthioxylulose 5-phosphate (MTXu-5P) (PubMed:23042035, PubMed:23035785).  The S-(methylsulfanyl)glutathione is reductively cleaved to relase methanethiol in a second reaction.  Involved in the MTA-isoprenoid shunt of the methionine salvage pathway (PubMed:23042035).
What are the official names of this protein?
1-methylthio-D-xylulose 5-phosphate methylsulfurylase, MTXu 5-P methylsulfurylase, 1-methylthio-xylulose 5-phosphate sulfo-lyase.
Protein: RL36_THEM4
Sequence: MKVQSSVKKRCEHCKIIKRKGRVYVICKVNPKHNQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: REV_HV1MA
Sequence: MAGRSGDSDEDLLRAIRLIKILYQSNPPPNTEGTTRQARRNRRRRWRARQRQINSIGERILSTYLGRPEEPVPLQLPPLERLTLNCNEDCGTSGTQGVGSPQISVESPAILGSGTEE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: HIS1_CLOK1
Sequence: MDGERKIKIALTKGRIEKEAVKIFERAGVDCSEVINKGRKLIFHNMESNIDFVLVKAPDVLTYVEHGVVDIGIVGKDTLLEQDKNFYEVLDLGFGKCKFSLAGLKDSNFYSGYNRKKIATKYPNVARSYFRKLGQDVEIIKIEGSVELAPILGLADAIVDIVETGSTLKENGLVIYKDICSISARMVVNMASMKMKKEEIEKIINKVQVQINEIEKAVR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_SULTO
Sequence: MNLLDIIIIGIVQGISEWLPISSKTQVLISSHYLLNLPIAIAYSFGLFMEMGSIGSATIYFRKDIMSVFRDRKLLLYLAIITIITGLVGVPLYIISDKLLKNAYDPSIPMIILGIALIVDGLYIRYSRIKIRSFKDLSLKNIILIGIAQGLAALPGVSRSGMTVSTMLFLGIKPDDAFRYSYLAYIPAAVGAVGTTILFSKTNISYVISLIGIGGVLISVISAFIIGMLTIDLLLRFAKRRNIYIIDFTLGGIAIVVSVLTILI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
What are the official names of this protein?
Undecaprenyl-diphosphatase, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS18_DEHMC
Sequence: MSIQDRPNRPARGGRGRYTPKRKICSFCAEKVSRIDYKDSAKLARYISDRGKIEPRRRTGTCARHQRALANAIKRARFIALMPFVSEHVRRQGNVATFSPIRELRPEPKIAEAKIEPKVEVKAEVAVPEVKAEVKPAAEASKPAESA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ATPE_HELPH
Sequence: MALLKISVVVPEGEVYTGEVKSVVLPGVEGEFGVLYGHSNMITLLQAGVVEIETENQKEHIAINWGYAEVTKERVDILADGAVFIKKESDDRDDAISRAKKLLEDASSDRLAVSSVLAKIESL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL24_SYNJA
Sequence: MVRPLKPSQIRRLIRQTGVRKHRNSLRYKMRIKKGDTVQVISGDDKGKIGEVLQVFPERNMVLVEGVNIVTYHRKPQREGESGRIETKEAPIHACKVMLYSKKQEVASRIGYQITADGRKVRVLKKTGEILD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PGTB1_BOVIN
Sequence: MAATEDERPTGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLNRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLSCLVILGDDLSRVNKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAINYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSENVHIST
What is the function of this protein?
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  Known substrates include RAC1, RAC2, RAP1A and RAP1B (By similarity).
What are the official names of this protein?
Geranylgeranyl transferase type-1 subunit beta, Geranylgeranyl transferase type I subunit beta, GGTase-I-beta, Type I protein geranyl-geranyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: MURQ_CLOB1
Sequence: MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLGVLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIGATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVERAKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MATK_ANDPO
Sequence: MXECKGYLELXRSXXHDFIYPLIFQEYIYALAHDRGLNRSIFFENAXYDNKSSLLIVKRLITHLIXQMYXQNHFLFYTNNFXPDPFGGYXTGVXSXMIFEGFGVVVEIPFYLRLLSFLEGKERVKSHNLRSLHSIFPFLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIRFFLHEYPNRNSLITPKKYSFSFSKRNKKFFLFLYNFHVYEYESIFVFLRNQSSHLCSISFETFLERILFYKKIELEVFAKHFKAILWVFKDPFLHYVRYRGKFILASKGSSLLMNKWEYYLVNFWKCYFYIWAQPRRIHIKQLSKNSLDFLGYLSNVRLKPSMVRSQMIENSFLIENAGKKLDTLVPITSMIGSLSKAKFCNVLGHPMNKPVWGGLSDSXIMERIRAXIXKSSHYYSXSLKKISLYXIKYILRLPGAKTLARKHKITVRSFLKRLGVGLLEEFFTEEEQVFYLTFPKASSTSRKLYQRRVWYLDIFYINDTPNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SFSA_SULAC
Sequence: MTTSSFVVYDFDTPLFEDIVKERINRFVVITQSGKLCHLHDPGRLKELIYPGNRILIREHKGRKTNYMVLAAHSGTGWVVTDSSIHNKIARNFLPSDVKSEVKVNNSRLDFYYDNTFVEVKGCSLVVDGKALFPDAPTERGKRHLEELIKLKMQGYRSLILILVMRDDAICFSPNWKTDKKFSMAFKNAVEEGVEVTIKLLKLIDNKIWYIKDIQLCPDAFNYSH
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RDRP_TNVA
Sequence: MELPNQHKQTAAEGFVSFLNWLCNPWRRQRTVNAAVAFQKDLLAIEDSEHLDDINECFEESAGAQSQRTKVVADGAYAPAKSNRTRRVRKQKKHKFVKYLVNEARAEFGLPKPTEANRLMVQHFLLRVCKDWGVVTAHVHGNVALALPLVFIPTEDDLLSRALMNTHATRAAVRGMDNVQGEGWWNNRLGIGGQVGLAFRSKXGCLERRPGFSTSVSRGEHPDLVVIPSGRPEKQRQLLRYSGIGGHLLIGIHNNSLSNLRRGLMERVFYVEGPNGLQDAPKPVKGAFRTLDKFRDLYTKNSWRHTPVTSEQFLMNYTGRKLTIYREAVDSLSHQPLSSRDAKLKTFVKAEKLNLSKKPDPAPRVIQPRSPRYNVCLGRYLRHYEHHAFKTIAKCFGEITVFKGFTLEQQGEIMRSKWNKYVNPVAVGLDASRFDQHVSVEALEYEHEFYLRDYPNDKQLKWLLKQQLCNVGTAFASDGIIKYKKKGCRMSGDMNTSLGNCILMCAMVYGLKEHLNINLSLANNGDDCVIVCEKADLKKLTSSIEPYFKQFGFKMEVEKPVDIFERIEFCQTQPVFDGSQYIMVRKPSVVTSKDVTSLIPCQTKAQYAEWLQAVGECGMSINGGIPVMQNFYQKLQTGIRRTKFTKTGEFQTNGLGYHSRYMHRVARVPSPETRLSFYLAFGITPDLQEALEIFYDTHKLELDDVIPTDTYQVSGEHLINGLPN
What is the function of this protein?
RNA-dependent RNA polymerase that plays an essential role in the virus replication.
What are the official names of this protein?
RNA-directed RNA polymerase, Protein p82.
What is the protein family that this protein belongs to?
Belongs to the tombusviridae RNA polymerase family.
Protein: GLRX2_PONAB
Sequence: MLWRRAALAGTRLVWSRSGSAGWLDRAAGAAATAASGMESNTSSSLENLETAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFRDMNVNYKVVELDLLEYGNQFQDALYKMTGGRTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ
What is the function of this protein?
Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.  Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.  Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.  Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.  Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex.  Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release (By similarity).
What are the official names of this protein?
Glutaredoxin-2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MIAB_DICNV
Sequence: MQTVLKHVYIETYGCQMNEYDSSKMLAVLKNSHGITPVATPEEADVLLLNTCSVREKAQEKVFSQLGRWKSLKERKPHLIIGVGGCVASQEGEMIRRRAPEVDVVFGPQTLHRLPNLIEEAQRSRGGVVDVSFPEIEKFDHLPEPRAEGPTAYVSVMEGCSKYCTYCVVPYTRGAEISRPFDDVLAECATLAAQGVREINLLGQNVNAYRGAMHDGTIADLALLIEYVAAIPNIGRIRFTTSHPSEFSDALIETYRRVPKLVSHLHLPVQSGSNRILALMKRDYKVAEYQEKLAKIRAIRPDISFSSDFIVGFPGEEEEDFQATMDLIEAVFFDTSYSFIYSQRPGTPASTMPDRVPLTVKKERLARLQARILEMAASISEAMVGTEQWVLVDRLSRKSEREVSGRTENNRVVNFSAPASLIGRFAKVQITAAYKNSLRGRLIEAELLPDPVVYTR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUGC_MYCTO
Sequence: MAEIVLDHVNKSYPDGHTAVRDLNLTIADGEFLILVGPSGCGKTTTLNMIAGLEDISSGELRIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNIAFPLTLAKMRKADIAQKVSETAKILDLTNLLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVQMRGEIAQLQRRLGTTTVYVTHDQTEAMTLGDRVVVMYGGIAQQIGTPEELYERPANLFVAGFIGSPAMNFFPARLTAIGLTLPFGEVTLAPEVQGVIAAHPKPENVIVGVRPEHIQDAALIDAYQRIRALTFQVKVNLVESLGADKYLYFTTESPAVHSVQLDELAEVEGESALHENQFVARVPAESKVAIGQSVELAFDTARLAVFDADSGANLTIPHRA
What is the function of this protein?
Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose.  Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M. tuberculosis.  Trehalose uptake is essential for virulence.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Trehalose import ATP-binding protein SugC, Nucleotide-binding domain of SugABC transporter, NBD of SugABC transporter, SugABC transporter ATPase SugC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.