PharMolix/UniProtQA huggingface dataset:
Protein: SYM1_BACAH
Sequence: MSIFIGGAWPYANGSLHLGHIASLLPGDILARYYRAKGENVLYVSGSDCNGTPIAIRAKQEGVTAKEIANKYHEEFERCFRNLGFTYDCYTRTDSEHHHETVQNVFLRLLEEGHIYKKTVEQAYCETCTQFLPDRYVEGVCPHCHEEARGDQCDACSAILDPLDLLEKKCKLCGSTPSIQETEHFYFALHTFQEQIKRAVEIAKQTGTWRDNAIQLTERYVKEGLLDRAVSRDLPIGVPIPVEGYEDKKIYVWIEAVTGYYSASKHWAEETGKDDREFWDSEAKTYYVHGKDNIPFHSVIWPAVLLGIGEGAIPRHIVSNEYLTVEKRKLSTSKNWAVWVPDILERYDPDSIRYFLTVNAPENRDTDFSWREFIYSHNSELLGAYGNFVNRTLKFIEKYYGGIMPKGSIDVELKDKIERLYKHVGEAIEQTKFKVALESIFDAVRFANKYFDERQPWKEREDDPVSCEETIYNCVYLIANFANLLEPFLPFSSERIRNTLSIVNRNWEPQHTLPTRIDSVKPLFERIDVKQIERELEKLYGAVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase 1, Methionyl-tRNA synthetase 1, MetRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFP4_BOVIN
Sequence: MAPLVGLFLIWAGASVFQQLHPVNGGDIPDPGSKPTPPGMADELPTETYDLPPEIYTTTFLPRTIYPQEEMPYDDKPFPSLLSKANDLNAVFEGPACAFPFTYKGKKYYMCTRKNSVLLWCSLDTEYQGNWKFCTERDEPECVFPFIYRKKSYESCTRVHSFFWRRWCSLTSNYDRDKAWKYC
What is the function of this protein?
Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation.  Displays heparin-, gelatin- and phospholipid-binding activities.
What are the official names of this protein?
Seminal plasma protein BSP-30 kDa, BSP-30K.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIBC_BACSU
Sequence: MKTIHITHPHHLIKEEQAKSVMALGYFDGVHLGHQKVIGTAKQIAEEKGLTLAVMTFHPHPSHVLGRDKEPKDLITPLEDKINQIEQLGTEVLYVVKFNEVFASLSPKQFIDQYIIGLNVQHAVAGFDFTYGKYGKGTMKTMPDDLDGKAGCTMVEKLTEQDKKISSSYIRTALQNGDVELANVLLGQPYFIKGIVIHGDKRGRTIGFPTANVGLNNSYIVPPTGVYAVKAEVNGEVYNGVCNIGYKPTFYEKRPEQPSIEVNLFDFNQEVYGAAIKIEWYKRIRSERKFNGIKELTEQIEKDKQEAIRYFSNLRK
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
What are the official names of this protein?
Bifunctional riboflavin kinase/FMN adenylyltransferase, Riboflavin biosynthesis protein RibF.
What is the protein family that this protein belongs to?
Belongs to the RibF family.
Protein: EFTS_CHESB
Sequence: MSISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGLIGLAADATSAVAVEVNSETDFVARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKSVADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVSEGLGKIGVLVAIETEGNAEAARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLRKFYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAEVAAAAKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_METAC
Sequence: MTLSPEDLKTIEKYALQNAVKYEKAPQSKAVMGKVMGECPQLRANPGAVSTALKSIVSEIAKGNPEAWKTRLSEIAPELIEALNVKKEPEKGLKPLEGAEPGKVVMRFAPNPNGPGTLGSARGMVVNSEYVKMYKGKFVLRFDDTDPDIKRPMLEAYDWYLDDFKWLGVVPDRVVYASDHFPIYYDYARKLIEMGKAYVCFCKGEDFKRLKDAKQACPHRDTSPEENLMHWEKMLAGEYEDQQAVLRIKTDIEHKDPALRDWGAFRIRKMSHPRAEIGNKYVVWPLLDFAGAIEDHELGMTHIIRGKDLIDSEKRQGYIYKYFGWTYPKTTHWGRVKIHEFGKFSTSSLRKAIEAGEYSGWDDPRLPTIRAIRRRGIQAEALKKFMIEMGVGMTDVSISMESLYAENRKIVDPVANRYFFVWAPVELEIAGMEPTVAKLPLHPTDHSRGVREIAVGNKVLVCAEDVEKLELGSVIRLKDFCNIEITSLSPLQAKHSDVSLEALKKAKAKIVHWAPVDGISVKVRGPEGDLEGIGEKGIVGELDKIVQFERFGFCRIDAVSEEKVVAYFAHK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1581_LACLM
Sequence: MDIQNIKETIAMIEEQNFDIRTITMGISLLDCIDADIDKTAEKIYQKIVNKAGKLVEVGNEIGHELGIKIVNKRVSVTPIAIIGAATAADDYTPLALAMDRAAKEIGIDFIGGYSALVQKGYQKGDEILIKSMPKALAATERVCASVNVGSTKSGINMTAVRDMGETIKIMSKGDKWLNAKLVVFANAVEDNPFMAGAFHGVGEADTIINVGVSGPGVVKRALEKVRGESFDILAETIKKTAFKITRIGQLVGQMASERLNVEFGIVDLSLAPTPAIGDSVARVLEEMGLETVGTHGTTAALAMLNDAVKKGGVMAAERVGGLSGAFIPVSEDEGMIAAVNSGALNIEKLEAMTCVCSVGLDMIAIPEETPASTIAAMIADEAAIGVINQKTTAVRIIPMGKEGEQIEFGGLFGVAPVMRVNKASSADFIARGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein llmg_1581.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RL24_CHLL2
Sequence: MKTGIKKVKLHVKKNDSVVVISGNDKGKAGKVLRVYPQKGRVIIEGVNIRKRHMKPTQSHPQGSIIEREFPIHASNVKKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL21_METLZ
Sequence: MAKHNGIKKRTRYKLQKTLRTRGMPNVTKVIQNFDEGQKVHLVLDSSVQKGQPHPRFHGKTGTIVGKRGRAWLLEIKDGNATKTVIARPQHLTAQKYN
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: RS11_MYCSP
Sequence: MAKKNKKVVTQGIAHIHSTYQNTIVSFSDLKGNVFAWSSSGAIGYKGTKKKTPYAAGLAAAAAVEKAKEFGLKEVSILVKGVGPGKSTARKQIETSGFTIKDVKDVTPTPHNGTRPPKKILKREK
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: BGL01_ARATH
Sequence: MEDVLTLITMIVLLLLAFHGFGKCSSDLYSRSDFPEGFVFGAGISAYQWEGAVDEDGRKPSVWDTFLHCRKMDNGDIACDGYHKYKEDVQLMAETGLHTFRFSISWSRLISNGRGSINPKGLQFYKNFIQELVKHGIEPHVTLHHYDFPQYLEDDYGGWTNRKIIKDFTAYADVCFREFGNHVKFWTTINEANIFTIGGYNDGNSPPGRCSFPGRNCTLGNSSTETYIVGHNLLLAHASVSRLYKQKYKDIQGGSVGFSLFAMNFTPSTNSKDDEIATKRANDFYLGWMLEPLIYGDYPDVMKRTIGSRLPVFSKEESEQVKGSSDFIGVIHYLTALVTNIDINPSLSGIPDFNSDMGESINILSMRVRISRLPNSDEKCLIFFITLSILEYIKQSYGNPPVYILENGKTMNQDLELQQKDTPRIEYLDAYIGAVLKAVRNGSDTRGYFVWSFMDLYELLNGYKSSFGLYSVNFSDPHRKRSPKLSAHWYSGFLKGKPTFLGSQGITQLHSNFSSSR
What are the official names of this protein?
Beta-glucosidase 1, AtBGLU1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: NEUT_BOVIN
Sequence: MMAGMKIQLVCMILLAFSSWSLCSDSEEEMKALETDLLTNMHTSKISKASVPSWKMSLLNVCSLINNLNSQAEETGEFHEEELITRRKFPAALDGFSLEAMLTIYQLQKICHSRAFQHWELIQEDILDAGNDKNEKEEVIKRKIPYILKRQLYENKPRRPYILKRGSYYY
What is the function of this protein?
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism.  It causes contraction of smooth muscle.
What are the official names of this protein?
Neurotensin/neuromedin N.
What is the protein family that this protein belongs to?
Belongs to the neurotensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Protein: LPXD_BURP1
Sequence: MALTLEALAARFGGEIVGDGRCEVRALAPLDQAGPRQLAFLANPKYLAQVETTGAGAVLIAPGDLEKLGAAAHGRNFIVTPNPYAYFARVAQMFIDLAAPPRAAGVHPSATIDPAAQVAASAVIGPHVTVEAGAVIGERAQLDANVFVGRGTRIGDDSHLYPNVAIYHGCTLGPRAIVHSGAVIGSDGFGFAPDFVGEGDARTGAWVKIPQVGGVKVGPDVEIGANTTIDRGAMADTVIDECVKIDNLVQIGHNCRIGAYTVIAGCAGIAGSTTIGKHCMIGGAVGIAGHVTLGDYVIVTAKSGVSKSLPKAGIYTSAFPAVEHGDWNRSAALVRNLDKLRDRIKALETALAAREGDAGGA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LEU3_CANBO
Sequence: MSIIEKKIVLLPGDHVGVEVVEEAVKILKSISEVKPEIQFKFENHLIGGAAIDATGVPLPDEALEAAKKSDAVLLGAVGGPKWGTGEVRPEQGLLKIRKELNLYANLRPCNFASDKLLDLSPLKSDIVKGTDFTVVRELVGGIYFGDRVEDDGSGFASDSESYSVPEVERITRMAAFLSLQNDPPLPIWSLDKANVLASSRLWRKTVDRVIKEEFPKLTVQHQLIDSAAMILVKSPTKLNGIVITNNMFGDIISDEASVIPGSLGLLPSASLASLPDTNQAFGLYEPCHGSAPDLPKNKVNPIATILSAAMMLKLSLNLVKEGNAVEEAVRKVLDQGIMTGDLGGNNSTTEVGDAIAKEVKLLLA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP1_YEAST
Sequence: MSYDKKADVTSLDEDLRQLRESKFSPEAIQNIKIWVYKSVLKEIAPPGDLLECLKDGTVLCKLANILYEADTGEANHISWKSSKMPFVQMDQISQFLSFSRKYGVPEDELFQTIDLFEKKDPAIVFQTLKSLSRYANKKHTDRFPVLGPQLSTKKPRPPVKSKPKHLQDGTGWSTFEYGYMKGASQATEGVVLGQRRDIV
What is the function of this protein?
Has actin-binding and actin-bundling activity.  Stabilizes actin filaments against disassembly.
What are the official names of this protein?
Transgelin, Calponin homolog 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein: ACCA_ECOLU
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPTICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_DEHMC
Sequence: MAKLKLDIVTAERSVFSEEVDVVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGTEEYSLVVSGGFLEVRPDRVVVLADSAERAEEIDIARAIEAKKRAEASMADKYVPGMLAAETEASLRRAMVRLKVAEKRRKHPQV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FOLD_BACCN
Sequence: MVAVIIKGNEVAEKKRAQLKEEVVKLKEQGIVPGLAVILVGEDPASRSYIKGKQKGCEQVGIYSELIEFPDTITEERLLAEIDRLNEDDRINGILVQLPLPKHIEEKAIIERISPKKDVDGFHPINIGRMMTGQDTFLPCTPHGILELVKETNIDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTKNIKELSKLADILVVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFENVLDIAGYITPVPKGVGPMTITMLLHNTVESAKRAGFICK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DAPD_JANSC
Sequence: MSNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQWAKKAVLLGFRLKDMEMQGGSAQGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAYIAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAGSLPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1059_MYCSK
Sequence: MARAEGDSWDVASSVGATAAMVAAGRAVATRDPRGLIDDPYAAPLVRAVGIEFFTKVADGEFDITELDPSSAAEMQARIDEMALRTRFFDDYFLASTAGGIRQVVILASGLDSRAYRLPWPDGTVVYEIDQPAVIDFKTSILAGIGAEPTAERRTVAIDLREDWPAALRVAGFDSAAPTAWCAEGLLIYLPPEAQDLLFDNVTALSAAGSTVATEYVPGILNFDAEKARAASAQMRERGLDLDMPSLVYHGERKHVMEYLTSLGWTMAGLPRTDLFAKHGVPMVAHDNDPLGEIVYVSGTYQNR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mkms_1059.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: H1FNT_MOUSE
Sequence: MAEAVQPSGESQGAELTIQIQQPAERALRTPAKRGTQSVLRVSQLLLRAIAGHQHLTLDALKKELGNAGYEVRREISSHHEGKSTRLEKGTLLRVSGSDAAGYFRVWKISKPREKAGQSRLTLGSHSSGKTVLKSPRPLRPRSRRKAAKKAREVWRRKARALKARSRRVRTRSTSGARSRTRSRASSRATSRATSRARSRARSRAQSSARSSARSSAKSSAKSSTRSSAKSWARSKARSRARSRAKDLVRSKAREQAQAREQARARAREQAHARARTQDWVRAKAQEFVSAKEQQYVRAKEQERAKAREQVRIGARDEARIKAKDYNRVRPTKEDTSPRPAEEKSSNSKLREEKGQEPERPVKQTIQKPALDNAPSIQGKACTKSFTKSGQPGDTESP
What is the function of this protein?
Essential for normal spermatogenesis and male fertility.  Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis.  Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm.  Binds both double-stranded and single-stranded DNA, ATP and protamine-1.
What are the official names of this protein?
Testis-specific H1 histone, Haploid germ cell-specific nuclear protein 1, Histone H1.7, Histone H1t2.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole.
Protein: LHA_CHLAA
Sequence: MQPRSPVRTNIVIFTILGFVVALLIHFIVLSSPEYNWLSNAEGGALLLSAARALFGI
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-808/866 alpha chain, Antenna pigment protein alpha chain, Bacteriochlorophyll a-binding protein.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: TRMD_YERPN
Sequence: MWIGVISLFPEMFRAITDYGVTGRAVKNGLLSVQCWSPRDFTYDRHRTVDDRPYGGGPGMLMMVQPLREAIHAAKAAAGEGAKVIYLSPQGRKLDQQGVCELAMNQKMILVCGRYEGVDERVIKTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHHASAEEDSFVDGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLESLALTDEQMVLLAEFQREHKP
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_YERPB
Sequence: MKAIVFAYHDIGCVGLNALAEAGYDIQAVFTHTDNPGENRFFSSVARVAADLALPVFAPEDVNHPLWVERIRELQPDIIFSFYYRNMLSDEILSLAPQGGFNLHGSLLPQYRGRAPINWVLVNGETETGVTLHQMVKKADAGPIAGQYKVAISDVDTALTLHAKMRDAAQELLRNLLPRMKEGPLPLTPQKEADASYFGRRTAADGEIHWQKSAFTINNLVRAVTEPYPGAFSYLGQRKLTIWRSRPLDLVHNKLPGTVLSTAPLTVACGEGALEIITGQGEAGLYVQGDRLAQEMGIVTDVRLGNKPSNTLKRRTRVLILGVNGFIGNHLTERLLQDDRYEVYGLDIGSDAISRFLGNPAFHFVEGDISIHSEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGVKEGLKFTLFRPFNWMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRIIENRDGCCDGQIINIGNPTNEASIRELAEMLLTSFENHELRDHFPPFAGFKDIESSAYYGKGYQDVEYRTPSIKNARRILHWQPEIAMQQTVTETLDFFLRAAVIEKTAAPKDELNA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: CR13_RANCA
Sequence: GLLSVLGSVAQHVLPHVVPVIAEHL
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-1.3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_BRUAB
Sequence: MATKAAFARMNGLGNQIIVADMRGRADSITSAAAIRLASDSETAFDQIMAIHDPRTPGTDYYIAIINCDGTQAQACGNGTRCVVQALAAETGRHAFTFETRAGILTATEHDDGLISVDMGTPRFDWQDIPLAQAVADTRKIELQVGPADAPVLHSPSIASMGNPHAVFWVDKDVWSYELDKFGPLLENHPIFPERANISIAHVTSSDTIDLRTWERGAGLTRACGSAACAAAVSAARTGRTGRKVTVNVPGGPLLIEWRDDDHVMMTGPAEWEFSGTFDPATGEWSRDTQGLQGSGNADRGAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_TAVCV
Sequence: MSYINIPDDVVSKYSDDLKTFTQKAGEIPSSKSLIPQTAYTIAALKTKLKFWEVTAKDDPTIASDWAGVCTAITAGTFSATNLKTVCELAFNLRKPHETGNVFIHTVPSDWTSSISTDSVDTTPIPATESDATLSTVSAAVQSGAAEDAATKAKAISFLCCALIRLSVKEPSHIMTAITSIRQRFGSLYGLASATLNAITFTRQQLSRIKQGIETYSLARGTIFYYVRYADTTYGSSDKSYGVCRFLLFQHLELEGMHIYKMILALLTEWSTVPIGLLLTWIRNPKSALAVVEIKNIITNFDKAGVDKSWKYSRMIDNTFFLNISSRRNVYMCALLASLNKRHVPQGVGDYADPRNIAVIKAMDAAVKNQVAIDVTLVERIYEKYLISAGSTDAGTAYTLSRGTKRPNPAVFMSHQQAEGHPTKKRTWKSMVPPPPTLQLEDQQQRRLSPELCEDCFSELLRGKHHRILPPPVIPSSSSEVLFSKSRIMEISGGCSFDPIGF
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TORD_SHEB9
Sequence: MSQVDINHARALVYQLLSSLFAREVDEQRLKELTSEAAQQFWEQLSLEANFTQSVDKIRSTLNGIKDDEALLELAADYCGLFLVGTKHSASPYASLYLSGEDEPLLFGQQHQQMSEFLHQSKLQVQSHFPEPADHLAVMLAYMAHLCCHSEDSVQLSFLQTCIDSWLAKFINQLTQCDKNGFYSAVATLTLAWVKQDIAQLEPAEAVIS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_HELPH
Sequence: MEIKMAKDYGFCFGVKRAIQIAEKNQNSLIFGSLIHNAKEINRLEKNFNVKIEEDPKKIPKNKSVIIRTHGIPKQDLEYLKNKGVKITDATCPYVIKPQQIVESMSKEGYQIVLFGDINHPEVKGVISYATNQALVVNSLEELQEKKLQRKVALVSQTTKQTPKLLQIASYLVERCTEVRIFNTICNATSYNQKAALDLSKEVDIMIVVGGKTSSNTKQLLSIAKQHCKDSYLVEDENELELAWFKDKKLCGITAGASTPDWIIENVKQKISTI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DADA_SALPK
Sequence: MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYMENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTFRFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMVVRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQLLSDILSGRTPAIPYDDLSVARYRSDFTPTRPQRLHSAHN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: K1PF_HAEIN
Sequence: MASVVTITLNAAYDLVGRLNRIQLGEVNTVETLGLFPAGKGINVAKVLKDLGVNVAVGGFLGKDNSADFEQMFNQHGLEDKFHRVDGKTRINVKITETEADVTDLNFLGYQISPQVWQQFVTDSLAYCLNYDIVAVCGSLPRGVSPELFADWLNQLHQAGVKVVLDSSNAALTAGLKAKPWLVKPNHRELEAWVGHPLNSLEEIIAAAQQLKAEGIENVIISMGAKGSLWINNEGVLKAEPAQCENVVSTVGAGDSMVAGLIYGFEKGLSKTETLAFATAVSAFAVSQSNVGVSDLSLLDPILEKVQITMIEG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.
What are the official names of this protein?
1-phosphofructokinase, Fructose 1-phosphate kinase, Fru1PK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.