PharMolix/UniProtQA huggingface dataset:
Protein: ASM3A_HUMAN
Sequence: MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQLYIKHNY
What is the function of this protein?
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088).  Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789).  Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088).  Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine.  Has in vitro activity with CDP-ethanolamine (PubMed:26783088).  Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088).
What are the official names of this protein?
Acid sphingomyelinase-like phosphodiesterase 3a, ASM-like phosphodiesterase 3a.
What is the protein family that this protein belongs to?
Belongs to the acid sphingomyelinase family.
Protein: O1635_CONCL
Sequence: MKLTCVLIVAVLILTACQVIAADEAEATNRAIKRGWFGEESSCWWCTGFNKCCEAAAVCQSVNSACP
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.35, O1_Cal6.35.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CEA18_HUMAN
Sequence: MDLSRPRWSLWRRVFLMASLLACGICQASGQIFITQTLGIKGYRTVVALDKVPEDVQEYSWYWGANDSAGNMIISHKPPSAQQPGPMYTGRERVNREGSLLIRPTALNDTGNYTVRVVAGNETQRATGWLEVLELGSNLGISVNASSLVENMDSVAADCLTNVTNITWYVNDVPTSSSDRMTISPDGKTLVILRVSRYDRTIQCMIESFPEIFQRSERISLTVAYGPDYVLLRSNPDDFNGIVTAEIGSQVEMECICYSFLDLKYHWIHNGSLLNFSDAKMNLSSLAWEQMGRYRCTVENPVTQLIMYMDVRIQAPHEDLTCCPQRFLHLRIHGDVPHHADSAGWRLHLWSPDPCSDQPLLNQDKSGSMSVHPRPEDKTRRASR
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 18.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
Protein: MNMG_SALPA
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKERWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREASGEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA1_PONAB
Sequence: MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMSATQLNPLVEQEQLSSNCVCQINRFIVNTLKDGRRVVILMELEVLKSAEVVGVKIGNPVPYNEGLGQPQVAPPAPAASPAASSRPQPQNGTSGAGSTVSKAYGASKTFGKAAGPSLSHNSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEEKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLPTVQFDFTGIDDLENKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLMDTSGKVVTATLWGEDADKFDGSRQPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEAYKLRGWFDAEGQALDGVSISDLKSGGVGGGNTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEAILGQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYREYGRRLVMSIRRSALM
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.  In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.  Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response.  It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.  Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair.  Also plays a role in base excision repair (BER) probably through interaction with UNG.  Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage.  May also play a role in telomere maintenance.
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: DAD2_ARATH
Sequence: MVKSTSKDAQDLFHSLHSAYTATPTNLKIIDLYVCFAVFTALIQVAYMALVGSFPFNSFLSGVLSCIGTAVLAVCLRIQVNKENKEFKDLAPERAFADFVLCNLVLHLVIINFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD2, Oligosaccharyl transferase subunit DAD2, Defender against cell death 2, AtDAD2, DAD-2.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS19_BURL3
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: LECC1_CENMI
Sequence: SDSLSFSFINFDKDERNVIAQGDARLVGNNILQLTRTDSNGSPVKSTVGRILYVAQVRLWEKSTNRVANFQSQFSFFLESPLSNPADGIAFFIAPPDTAIPSGSAGGLLGLFSPKTAQNESANQVLAVEFDTFYAQNSNTWDPNYPHIGIDVNSIKSAKTVRWERREGVTLNVLVTYNPSTRTIDVVATYPDGQRYDLSVVVDVTTVLPEWVRVGFSAASGEQFQTHNLESWSFTSTLLYTAQKENN
What is the function of this protein?
Mannose-specific lectin.  Also binds alpha-methyl-D-mannoside, D-glucose, N-acetyl-D-glucosamine and sucrose but not D-galactose, D-arabinose, D-fructose, D-xylose, lactose or glycoproteins fetiun, PSM and ovalbumin.  Shows agglutinating activity towards rabbit erythrocytes.
What are the official names of this protein?
Mannose-specific lectin CML-2.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: FSD1_DANRE
Sequence: MDDQKESLRKIITTLALKNEEIQNFICSLKQSLENLEANSNRVQEDLESEFSSLHSVLDDLKEGMVTRIKQERASRTYELQSQLGACTKALESSEELLEFANQTLCSSENDSFTQAAKDIKDSVTMAPAFRLSLKAKASDSMNHMMVDFTHERNLLQSITFLPVPATPEIHVADCQVFDNTVTVVWTLPEPDSKIDHYILEHRKTNHEGPPRAREDYPWMVVEGIKETEYTLTGVRFDTRYMTFRVKACNKAVAGEFSEPVTLETHAFVFKLDASSSHQNLKVEDLSVEWDSSGGKVAVQDIRKEKNRTNSPMHSPARTAMMSPKRAPSARVGRDRFTAESYTVLGDTMIDAGQHYWEVRFDKESKAFAAGVALRSLGRFDQLGKSNASWCIHLNNWLQQSLTAKHNNKARTLDCSIPDRIGIYCNYEEGTLSFYNSRNKTLLHTFRTKFQQPVIPAFMVWNGSFSVQTGLQVPSIVLSGQKRNSNTSSSNASLT
What is the function of this protein?
May be involved in microtubule organization and stabilization.
What are the official names of this protein?
Fibronectin type III and SPRY domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle (By similarity).
Protein: RL31B_CLAM3
Sequence: MKTDIHPKYAPVVFRDLASGATFLTRSTVSSSKTIEWEDGNTYAVIDVEISSESHPFYTGKQRIMDSAGRVEKFNSRYAGFGTKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: TGT_FRATT
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPINSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSPLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: Y5247_DICDI
Sequence: MIIQKILQGAVLDIVQKKLVDKLASNKQFQQMSVQFKDKMDEITGEKPAKRNIHGHNNHTRSSNHPHSGAHSNINHNNNNNINFQNVKYTNDIHENARIYEQQRRLQQNGGGGDSSSSRSSNNNNSTNDNKPQSKNYFTHLFESFKEELNDEADKLNGKKK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280905.
Protein: UVRA_BRUAB
Sequence: MSDQKFISIRGAREHNLKNVDLDLPRDKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLEMMQKPDVDQIDGLSPAISIEQKTTSRNPRSTVGTVTEIYDYMRLLFARVGIPYSPATGLPIESQTVSQMVDRVIALEEGTRLYILAPIVRGRKGEYRKELAELQKKGFQRVKVDGTFYEIADVPPLDKKYKHDIDVVVDRVVVRPDLSTRLADSLETCLKLADGLAIAEFADKPLPVGETAEGGSANKSANETHERILFSEKFACPVSGFTIPEIEPRLFSFNNPFGACPTCDGLGTQQAIDPNLIIPDESAALKDGAVAPWARSSSPYYNQTLEALGKAYGFKVSARWSELSEEARQAILYGTKGREITFHYDDGLRSYQTTKPFEGVIPNLERRWKETDSAWSREEIERFMASTPCPACNGYRLKPEALSVKIGKKHIGEITEMSIRKADAWFRDIDGSFNEKQREIAARILKAIRERLQFLNNVGLDYLTLARNSGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQRDNARLLDTLRHLRDLGNTVIVVEHDEDAILTADYVVDIGPAAGVHGGKVIAQGSPQDIMANTNSLTGKYLSGAMEVAVPAERRKISKTKRLRVVGARGNNLKNVSADIPLGTFTAVTGVSGGGKSTFLIETLFKAASRRIMGSREHPAEHDRIEGLEFLDKVIDIDQSPIGRTPRSNPATYTGAFTPIRDWFAGLPEAKARGYQPGRFSFNVKGGRCEACQGDGVIKIEMHFLPDVYVTCDVCHGKRYNRETLDVLFKGKSIADVLDMTVEEGAEFFSAVPAVRDKLETLVKVGLGYIKVGQQATTLSGGEAQRVKLAKELSRRATGRTLYILDEPTTGLHFHDVAKLLEVLHELVEQGNTVVVIEHNLEVIKTADWVIDLGPEGGDGGGEIVAVGRPEDIVQEKRSYTGQFLKELLERRPKRSSQAAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_ESCF3
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEYGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CHLTE
Sequence: MKTYRRQLREKIIQALYTLELRDVDTDSAANWLLTKEIMDDPNAMKFFNHLMQSIVRNREEIDRYIAKHTFNWDMSRIAIIDKNILRMALAEILYCEDIPPKVSINEAIEIAKKFSSTDKSSKFVNGILDAIFNDMKAEGRIKKCGRGLVDHSEQKMQKTENNR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HIM1_YEAST
Sequence: MSYSVNTFTDYVLLFGSSSLVGKGILENLLDINLYIKNVSDLQGKLDSLSEIKGNVVLNKHVFCVNRRCINEEKSFMKTIDYINMRSVTWQGGRYYLRSRKEKDTEKVPSSPNTFCYDNFEEGFIKNTPEERGKDGYSFVYNQKQFSYTLHYACGKEKGIEIICNFTVTQLIIPRSETWPKLLPRIFSGTQKLEKFDIDNKNYVPGRSLPSLCDISTMVCSLGSTSARVRRTQVPSSFADYYLPFNLAQEFTNTTNKRLVVTTAFNNDFLSKTFEYFRIKAKLENDLDEALPNKLKELVILRPGPMCGQHGNPINVELGKENSTFLEKIFYYPHYLLVYKKKYISEARRIGLRTKLSEIIASSIYRMPGSALLGYAVPVSKVSYVASLMAIERKSKEAGPKLEVISSYQIDMIV
What is the function of this protein?
May participate in the control of processing of mutational intermediates appearing during error-prone bypass of DNA damage.
What are the official names of this protein?
Protein HIM1, High induction of mutagenesis protein 1.
Protein: YLPA_CAEEL
Sequence: MNAMFHSLFALSFVSLVASINNQNSRYDKMFLAMVCQDQNGCEVNIRFLKQSFPDSNSTEPLYEHTMIYNNGSLDEITIDVTEDVNIIEFTFTAPDENGTTIVETDSWELNFSETYFHTIGSLQLVGNLPCGRYGCPQTPLCNGSCRFMVIVSLAAFCISVLAGLALQTVYVSFLGFRKTRKAVELRDTLRLTEAAELAH
What are the official names of this protein?
Uncharacterized protein F02A9.1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACTC_PLATR
Sequence: MCDEDVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVIDSGDGVTHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTASTSSSLEKSYELPDGQVITIGNERFRCPEAMYQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PANB_CLOBM
Sequence: MRNTVSTFQELKNKGEKITMLTAYDYSMAKLIDSSGINGILVGDSLGMVCLGYENTLSVTMEDMLHHTKAVVRGTSNALVVGDMPFMSYQTSIYDAVYNAGRFIKEAGAHAVKLEGGATVAEEIKAIVKAQIPVMGHIGLTPQSVNMFGGFKVQGKNEKVAKKLIEDAKILEEAGAFAIVLECIPEKLSKIISESISIPTIGIGAGKYCDGQILVYQDMLSMFSDFKPKFVKSFGSIGESIKDGVSQYIKEVKEAKFPEEKHAFKIDDDVINKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2812_SACD2
Sequence: MLLKIPNVLSKEQVETAKSKLLDADWADGNITAGYQSAKAKNNLQLPENSPIAIELGDIVLTALAQNNMFMSAALPLKIFPPLFNCYQGGRSFGVHVDNAIRQVPGTPVKVRTDISMTLFLSEPDEYEGGELVIEDTYGSQSVKLAAGDMVLYPATSLHSVTPVTKGRRLASFFWLQSMVNSDEKRTLLFDMDMAIQSLRAQVDDSPEIVQLTGVYHNLLRQWAQT
What are the official names of this protein?
PKHD-type hydroxylase Sde_2812.
Protein: NLE1_BOVIN
Sequence: MAAAAAADEAATRDVQRLLVQFQDEGGQLLGSPFDVPVDITPDKLQLVCNALLAQEDPLPLAFYVHDAEIVSSLGRTLESQAVETEKVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRALTGHSKWITALSWEPLHANPECRYVASSSKDGSVRVWDTTAGRCERTLTGHAQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNAQDLRGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVVFSPDSRVIASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLSTDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR
What is the function of this protein?
Plays a role in regulating Notch activity.  Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity.  Required during embryogenesis for inner mass cell survival (By similarity).
What are the official names of this protein?
Notchless protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NLE1/RSA4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PMD1_LOCMI
Sequence: SCTEKTCPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCIQ
What are the official names of this protein?
Pars intercerebralis major peptide D1, PMP-D1.
What is the protein family that this protein belongs to?
Belongs to the granulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SOP14_ARATH
Sequence: MAAKTSNLVALLLSLFLLLLSISSQVGLGEAKRNLRNNLRLDCVSHPSPPPPHRSMAPPIFVPPSTSHKGQGP
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (PubMed:33514716, PubMed:34535661, PubMed:31001913).  Inhibits root growth and regulates root meristems (PubMed:34535661, PubMed:31001913).  Prevents general growth and development (PubMed:31001913).  Exhibits antibacterial effects against Pseudomonas syringae pv.  tomato DC3000, Ralstonia solanacearum, Bacillus subtilis and Agrobacterium tumefaciens, thus being an antimicrobial peptide (AMP) (PubMed:31001913).
What are the official names of this protein?
Serine rich endogenous peptide 14, AtSCOOP14, Phytocytokine SCOOP14, Precursor of serine rich endogenous peptide phytocytokine 14, Secreted transmembrane peptide 2.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Protein: POA1_YARLI
Sequence: MGYRLSALTYVQGDLFEESPRPAVLAHACNCLGSWGSGVAAGFKQKFPGAFVEYKRHCDKYSDDNSALLGTCQLIETHDAQTGELVYVACLFTSVRFGARVDGPEQIVKQTKLAMQDLQKQLAKMSGPIDGNSTVHMPKINAGLFRVPWRDTEKVLEEVGQPCTVYVID
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.
Protein: NQOR_ECOBW
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RL23_METCA
Sequence: MNQIELMRTLIAPVVSEKSTAGAEKNRQFVFRVKPAASKLQIKSAVELMFGVKVDSVRILNVKGKSKRFGRFMGQRSDWKKAYVKLKPGFDIELAVN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: LGT_RHIWR
Sequence: MQQAVIANAAQAIHWADLGLNPIALDLGFLQIHWYSLAYISGILLGWYYLTRLIAQPGAPMARRHADDLVFYATLGILIGGRLAYVFFYQPDILLHPLDVLKLWQGGMSFHGGALGVAAGIFYMARRNGLSWLRIHDYVACCAPFGLFFGRIANFVNGELWGRPTDVSWAMIFPGAPDGLPRHPSQLYEAGLEGIVLGLVLSFFFWRTDARNQPGKLVGIFLLGYGLSRFVVEYFREPDAQLGTLSWGLTMGQTLTVPMLIGGLYLIATASKRTPINAD
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1452_STAAN
Sequence: MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
What are the official names of this protein?
UPF0337 protein SA1452.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: MSHD_STRAW
Sequence: MTSDDTVWPGAGRSIETLAALSPGQAEAVLALLDEAARVDGQPAVSEQGRLQLRGGEREGVRHLLLSAGDTLVGYAQLEDTDPVEAPAAELVVHPAHRGRGHGRALGTALLAATGKRLRAWAHGGHSAARHLAQVLGLTLFRELRQMRRPLAGLDLAEPKLPDGVTVRAFVPGQDDAAWLAVNAAAFAHHPEQGSLTQRDLDDRKAEPWFDPAGFFLAERDGELIGFHWTKVHAQEGIGEVYVLGVRPGAQGGGLGKALTTIGLRHLEAQGLPTAMLYVDADNKAAVSVYERLGFATHETDLMYRTES
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: OPAE_NEIGO
Sequence: AGEDHGRGPYVQADLAYAYEHITHDYPEQTGTKKDKISTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWNDNKYSVDIKELENKNQNKRDLKTENQENGTFHAVSSLGLSAVYDFKLNDKFKPYIGARVAYGHVRHSIDSTKKTTKFLTSSYGGLNPTVYTEENTQNAHHQSNSIRRVGLGVIAGVGFDITPKLTLDTGYRYHYWGRLENTRFKTHEASLGVRYRF
What is the function of this protein?
Implicated in a number of adherence functions.  OPA proteins are implicated in pathogenesis and are subject to phase variation.
What are the official names of this protein?
Opacity protein opA55.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
What are the subcellular locations of this protein?
Cell outer membrane.