PharMolix/UniProtQA huggingface dataset:
Protein: RL15_CLOB1
Sequence: MKLHELKAAEGANKASKRVGRGTGSGLGKTSGRGQNGQNSRSGGGVRPGFEGGQMPLYRRLPKRGFKNIFAKEYAAINLDRLNCFEDGTVVTPELLVEKRVVKKVKDGVKILGNGNIEKKLTVKAAKFSKSAIEKIEAAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y974_TREPA
Sequence: MMIDKLSGLDPVQNLRASCASEHVARAPAGDEITVSAEAQKKAELYLALEAVRSAPDVREYKIAAAEQKLADPAYLERALSHVVERFLEEQNL
What are the official names of this protein?
Uncharacterized protein TP_0974.
Protein: EFEMO_STAAM
Sequence: MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQATKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDLDPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKADTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANVEGAQKIYDLFKPILEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPLSKMAVITE
What are the official names of this protein?
Efem/EfeO family lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL9_METC4
Sequence: MEVILLERVAKLGQMGETVNVRPGYARNFLLARGKALRATENNKKHFEAQRAQLEARNLERRNEAQTVAEKLDGQSFVLIRQSGETGVLYGSVSTRDLAEVVTKEGFSVERGQFVLNQPIKTLGLHTVPVTLHPEVEVKVTVNIARSPEEAERQARGESVTEREQFNLDDLGLEVGQALADAGEGADDRG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SK1_PERFU
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, PerFu-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSTB_HELMO
Sequence: MIRTKISAENLNLFYGDFHALKDINISMGERQVTALIGPSGCGKSTFLRCLNRMNDIIPTCRVQGKLMFEDSEIYHPDTDVVALRKRVGMVFQAPNPFPKSVYENVAYAPKLHGLKDKARLDEIVETSLRQAALWDEVKDRLHKPALGLSGGQQQRLCIARALAIQPEVLLMDEPTSALDPISTLKIEELIRELKQYYTIVIVTHNMQQAARISDKTAFFLVGDLVEFDDTEVIFTNPKDQRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RIMO_SALCH
Sequence: MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPRYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ALIB4
Sequence: MSDNKIYLCAISNIESGTCNEDCKFCTQSVKYKADIERYRRKEIEDIVNEAKKARANKAVGFCLVTAGTGLDDKRLDYVCRAADAVHKAVPDISLIACNGIASYEQLKELKKHGIENYNHNLETAREFYNEICTTHSWDDRYETCLNAKKAGLYLCTGGIFGLGETQENRISMLKSIASLEPMSVPINFFHPNDALPLVKNPLTKQEAFDLVKLARSYLPNQMLMIAGGRELMFGEEQYDVFKHGANALVVGDYLTTGGRDAQDDIDAVTALGYEIAFACHQ
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: FAPR_BACVZ
Sequence: MRRSKKERQKLLQQTIKSTPFITDEELAGKFGVSIQTIRLDRLELSIPELRERIKNVAEQTLDDEVKSLSLDEVIGEIIDLELDGQAISILEVRREHVFSRNQIARGHHLFAQANSLAVAVIDDELALTASANIRFTRQVKEGERVVAKAKVTAVEKEKGRTVVEVNSYVGEEVVFSGSFDMYRSKQS
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: BREF8_EUPBR
Sequence: MSGSSEPYSDEPSQHNTHRFIDQIPDYPWDDYSGPPLQQSRGYSSQDLSPLQTYYSSGLSVGLNGQTGGSESGGSQSGGSDYSYSQNVPASLLPPAFYLVRSDSYPGTGIESRLPNSYLLSYPPSPTDPNTYYMPETSQFLPSHDLSLSVQDSSEILDSLFPQQESPSVTSNDEFLVQILSSRPRPQCWDHGCNGREFSSMSNLLRHQRERAGAVTKAECPVCGAVFTRTTARNIHVFERCEGIGRSL
What is the function of this protein?
Probable C2H2-type zinc-finger transcription factor that may regulate the gene cluster that mediates the biosynthesis of brefeldin A (BFA), a protein transport inhibitor that shows antiviral, antifungal, and antitumor properties.
What are the official names of this protein?
Probable C2H2-type zinc-finger transcription factor orf8, Brefeldin A biosynthesis cluster protein orf8.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COMD4_HUMAN
Sequence: MRFRFCGDLDCPDWVLAEISTLAKMSSVKLRLLCSQVLKELLGQGIDYEKILKLTADAKFESGDVKATVAVLSFILSSAAKHSVDGESLSSELQQLGLPKEHAASLCRCYEEKQSPLQKHLRVCSLRMNRLAGVGWRVDYTLSSSLLQSVEEPMVHLRLEVAAAPGTPAQPVAMSLSADKFQVLLAELKQAQTLMSSLG
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  Down-regulates activation of NF-kappa-B.
What are the official names of this protein?
COMM domain-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYAA_BORPE
Sequence: MQQSHQAGYANAADRESGIPAAVLDGIKAVAKEKNATLMFRLVNPHSTSLIAEGVATKGLGVHAKSSDWGLQAGYIPVNPNLSKLFGRAPEVIARADNDVNSSLAHGHTAVDLTLSKERLDYLRQAGLVTGMADGVVASNHAGYEQFEFRVKETSDGRYAVQYRRKGGDDFEAVKVIGNAAGIPLTADIDMFAIMPHLSNFRDSARSSVTSGDSVTDYLARTRRAASEATGGLDRERIDLLWKIARAGARSAVGTEARRQFRYDGDMNIGVITDFELEVRNALNRRAHAVGAQDVVQHGTEQNNPFPEADEKIFVVSATGESQMLTRGQLKEYIGQQRGEGYVFYENRAYGVAGKSLFDDGLGAAPGVPSGRSKFSPDVLETVPASPGLRRPSLGAVERQDSGYDSLDGVGSRSFSLGEVSDMAAVEAAELEMTRQVLHAGARQDDAEPGVSGASAHWGQRALQGAQAVAAAQRLVHAIALMTQFGRAGSTNTPQEAASLSAAVFGLGEASSAVAETVSGFFRGSSRWAGGFGVAGGAMALGGGIAAAVGAGMSLTDDAPAGQKAAAGAEIALQLTGGTVELASSIALALAAARGVTSGLQVAGASAGAAAGALAAALSPMEIYGLVQQSHYADQLDKLAQESSAYGYEGDALLAQLYRDKTAAEGAVAGVSAVLSTVGAAVSIAAAASVVGAPVAVVTSLLTGALNGILRGVQQPIIEKLANDYARKIDELGGPQAYFEKNLQARHEQLANSDGLRKMLADLQAGWNASSVIGVQTTEISKSALELAAITGNADNLKSVDVFVDRFVQGERVAGQPVVLDVAAGGIDIASRKGERPALTFITPLAAPGEEQRRRTKTGKSEFTTFVEIVGKQDRWRIRDGAADTTIDLAKVVSQLVDANGVLKHSIKLDVIGGDGDDVVLANASRIHYDGGAGTNTVSYAALGRQDSITVSADGERFNVRKQLNNANVYREGVATQTTAYGKRTENVQYRHVELARVGQLVEVDTLEHVQHIIGGAGNDSITGNAHDNFLAGGSGDDRLDGGAGNDTLVGGEGQNTVIGGAGDDVFLQDLGVWSNQLDGGAGVDTVKYNVHQPSEERLERMGDTGIHADLQKGTVEKWPALNLFSVDHVKNIENLHGSRLNDRIAGDDQDNELWGHDGNDTIRGRGGDDILRGGLGLDTLYGEDGNDIFLQDDETVSDDIDGGAGLDTVDYSAMIHPGRIVAPHEYGFGIEADLSREWVRKASALGVDYYDNVRNVENVIGTSMKDVLIGDAQANTLMGQGGDDTVRGGDGDDLLFGGDGNDMLYGDAGNDTLYGGLGDDTLEGGAGNDWFGQTQAREHDVLRGGDGVDTVDYSQTGAHAGIAAGRIGLGILADLGAGRVDKLGEAGSSAYDTVSGIENVVGTELADRITGDAQANVLRGAGGADVLAGGEGDDVLLGGDGDDQLSGDAGRDRLYGEAGDDWFFQDAANAGNLLDGGDGRDTVDFSGPGRGLDAGAKGVFLSLGKGFASLMDEPETSNVLRNIENAVGSARDDVLIGDAGANVLNGLAGNDVLSGGAGDDVLLGDEGSDLLSGDAGNDDLFGGQGDDTYLFGVGYGHDTIYESGGGHDTIRINAGADQLWFARQGNDLEIRILGTDDALTVHDWYRDADHRVEIIHAANQAVDQAGIEKLVEAMAQYPDPGAAAAAPPAARVPDTLMQSLAVNWR
What is the function of this protein?
Hemolysin that forms small cation-selective membrane channels, leading to hemolytic activity (PubMed:8077197).  The hemolytic activity of CyaA is weak compared with that of the HlyA of E. coli (By similarity).
What are the official names of this protein?
Bifunctional hemolysin/adenylate cyclase, AC-HLY, ACT, Cyclolysin.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the RTX prokaryotic toxin family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [Hemolysin]: Host cell membrane; Multi-pass membrane protein.
Protein: ADPRS_CHICK
Sequence: MAAAGAGSGRAAVSRSRPPPARFRGCLAGALLGDCLGAVFEGRSVVKLPDLLSFLRGLEPPGGEGEPAGSARRETLSYTDDTAMSRCVVQSLLAKREFDEVDMAKRFAEEYKKEPNRGYGMAVVNVFKKLLSPQCSDVFEPARAQFNGKGSYGNGGAMRVAGIPLTYSDVQDVKKFAKLSAELTHANSLGYNGAILQALAVHLALQGEVSRETFLEQLISHMEDIEADDKSLTDARALGFEDLPFSRRLKKIKEFLELSSVPKEDVLFELGNGIAALRSVPTAIYSFLRCMEADPDIPEHYNNLQRTIIYCISLGGDTNTIATMAGAIAGAYYGEEQVPPSWEQSCEAFQETQKMANSLHELYCQQL
What is the function of this protein?
ADP-ribosylhydrolase that preferentially hydrolyzes the scissile alpha-O-linkage attached to the anomeric C1'' position of ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on serine and threonine, free poly(ADP-ribose) and O-acetyl-ADP-D-ribose.  Specifically acts as a serine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to serine residues on proteins, thereby playing a key role in DNA damage response.  Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.  Does not hydrolyze ADP-ribosyl-arginine, -cysteine, -diphthamide, or -asparagine bonds.  Also able to degrade protein free poly(ADP-ribose), which is synthesized in response to DNA damage: free poly(ADP-ribose) acts as a potent cell death signal and its degradation by ADPRHL2 protects cells from poly(ADP-ribose)-dependent cell death, a process named parthanatos (By similarity).  Also hydrolyzes free poly(ADP-ribose) in mitochondria.  Specifically digests O-acetyl-ADP-D-ribose, a product of deacetylation reactions catalyzed by sirtuins.  Specifically degrades 1''-O-acetyl-ADP-D-ribose isomer, rather than 2''-O-acetyl-ADP-D-ribose or 3''-O-acetyl-ADP-D-ribose isomers.
What are the official names of this protein?
ADP-ribosylhydrolase ARH3, ADP-ribose glycohydrolase ARH3, ADP-ribosylhydrolase 3, O-acetyl-ADP-ribose deacetylase ARH3, Poly(ADP-ribose) glycohydrolase ARH3, [Protein ADP-ribosylarginine] hydrolase-like protein 2, [Protein ADP-ribosylserine] hydrolase.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Mitochondrion matrix. Note=Recruited to DNA lesion regions following DNA damage; ADP-D-ribose-recognition is required for recruitment to DNA damage sites.
Protein: UL95_EHV2
Sequence: MFALASMTTSGDEALNARYKESVSLSVGLCESLPEQFKLIETPINSFLLVANVMPNDDRPWDSHPASGADFHNIRMPRLERLRALIRCDRGYNNGKGGEAGQRAGEDDERMDEGVPEEGAPRSPHPPPFAHYEVYDSWSWQRALRVDKDDVIREAVAELAKPANWQGTAVEDPLPLMWLLFYGRRSFCDDPECLYRARFGHPGPLLLPNYMYRPAEDASSFLAGLCRCVRSVYGCEFGGGSHVNPAQVPFDHGRFSEALRKLGAVDDAGAYVSRQCLVCRLYRQNLMSRGIIGGRGSSIVLGGSGKKYLTREVGTRRCLELGDIALYPSYDISLILDDLEASDGLRQ
What are the official names of this protein?
Gene 34 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL95 family.
Protein: RL22_LEIXX
Sequence: MVESIARVRHIRVTPMKARRVVNMIRGKQAQEALAILKFAPQGASEPVYKLVASAIANARVKADQSNTYLDEQDLYVSRAFVDEGTTLKRFQPRAQGRAFRINKRTSHITVVLATPDEAEAAQPAKKASTAKKASN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CHBG_SALTY
Sequence: MERVLIVNADDFGLSKGQNYGIVEAYRNGVVTSTTALVNGEAIDHAAQLSRELPALGVGMHFVLTLGKPVSEMPGLTRDGLLGKWIWQMAEEDTLPLDEIAHELACQYQRFIDVFGSEPTHLDSHHHVHMFPQIFPIVARFAAQRGIALRIDRQTVLNADDLPSDLRSTQGFSSEFYGEEITEACFLRILDASAHRGEASLEVMCHPAFVDNIIRQSAYCYPRLTELEVLTSASLKAAIAERGYRPGSFLDI
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ACIC5
Sequence: MSRIGNKPIPLPAGVKYTHAGGKVVVEGPKGKIEQVIPEGIKLETKDGHIHAIRETEKHAAVHGLTRALVFNAVEGVTKGWSKDLDIVGIGYRAELKGKDMVVFTLGYSHPIEFPLPTGITAVIDPKQTRVTVSGIDRQKVGQVAADMRSLRKPDPYKNKGVRYVGEKLKKKAGKAGSK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: WRK42_ARATH
Sequence: MFRFPVSLGGGPRENLKPSDEQHQRAVVNEVDFFRSAEKRDRVSREEQNIIADETHRVHVKRENSRVDDHDDRSTDHINIGLNLLTANTGSDESMVDDGLSVDMEEKRTKCENAQLREELKKASEDNQRLKQMLSQTTNNFNSLQMQLVAVMRQQEDHHHLATTENNDNVKNRHEVPEMVPRQFIDLGPHSDEVSSEERTTVRSGSPPSLLEKSSSRQNGKRVLVREESPETESNGWRNPNKVPKHHASSSICGGNGSENASSKVIEQAAAEATMRKARVSVRARSEAPMLSDGCQWRKYGQKMAKGNPCPRAYYRCTMAVGCPVRKQVQRCAEDRTILITTYEGNHNHPLPPAAMNMASTTTAAASMLLSGSTMSNQDGLMNPTNLLARTILPCSSSMATISASAPFPTITLDLTESPNGNNPTNNPLMQFSQRSGLVELNQSVLPHMMGQALYYNQQSKFSGLHMPSQPLNAGESVSAATAAIASNPNFAAALAAAITSIINGSNNQQNGNNNNSNVTTSNVDNRQ
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).  Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771).
What are the official names of this protein?
WRKY transcription factor 42, WRKY DNA-binding protein 42.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROC_GEOMG
Sequence: MLRYLTAGESHGPQLTAIIEGIPAGLKISEETINVDLARRQGGYGRGGRMLIEKDQVQILSGVRWGETIGSPVTLCVVNRDWVNWQEKMSPHERHRDDKIRVTRSRPGHADLPGAMKYNHRDVRNILERSSARETAMRVAVGSVARAFLASFGVTVSGFVVELGGIKAERRGLSSDRLRELAAKSELATYDPEAEARMKAFIDSVKDAGDTAGGVVEVVVTGAPVGLGSHVQWDRKLDARLAMAVMSIQAIKGVEIGLGFETARRPGSQVHDEIYFDSSRIAHGEATGFFRKTNNAGGIEGGITNGEEIVIRAAMKPIPTLYKPLSSVDMLTKEPFEATVERSDVCAVPAAAVVAESVVAIEIASAFLEKFGGDSLAEIRRNYDGYLDYLRSF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: MDTK_ECO81
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIM_BACAC
Sequence: MNTKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPDEVEAMLLAGKSANRNDVPVLFDPVGAGATSYRTEVARHIPAEIELAIIRGNAAEIANVINEKWEIKGVDAGAGNGNVVSIAKQAADELNTVAVITGKEDVVTDGERTIVIRNGHSILTKITGTGCLLTSVIGAFVAVEKDYVKAAVAALTFYGVAAELAAAKTVEKGPGSFQIEFLNQLANTTSGDIEKYGKIEVI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RS10_SHEDO
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: HRCA_CAUSK
Sequence: MTQLFSGFSAQTPSLTDLDGRARDIFRRVVESYLETGEPVGSRTISRGGVQLSPASIRNTMQDLAQLGLLDAPHSSAGRIPTHAGLRMFVDGLLEVGDIGEEERRTIESRLFAHGRSFEEAMGEASAILSGLAGGAGIVVTPVREGGVKHVEFVALGADQALAIMVFDDGTVENRLMKRSAGVTPASLQEASNFLNARLRGRTLNEAKTEMAAELDTARRELDATAARLVEDGLAAWSGGDDPDRALIVRGRANLLADASAREDLERVRRLFDDLEQKGQLIGLLDDVRSAEGVRIFIGAETRLFSLSGSSLIAAPYMSGRQKVLGAIGVIGPTRLNYARVIPLVDYTARVLGRMMDG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL18_STRPG
Sequence: MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MA2B2_HUMAN
Sequence: MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWDLSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ
What are the official names of this protein?
Epididymis-specific alpha-mannosidase, Alpha-1,6-mannosidase, Mannosidase alpha class 2B member 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOXF1_MOUSE
Sequence: MSAPDKQQPPHGGGTGGGGGAGGQAMDPAAAGPTKAKKTNAGVRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPVYSMVNGLGFNHLPDTYGFQGSGGLSCAPNSLALEGGLGMMNGHLAGNVDGMALPSHSVPHLPSNGGHSYMGGCGGSAAGEYPHHDSSVPASPLLPAGAGGVMEPHAVYSSSAAAWPPAASAALNSGASYIKQQPLSPCNPAANPLSGSISTHSLEQPYLHQNSHNGPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHTTGGGSYYHQQVTYQDIKPCVM
What is the function of this protein?
Probable transcription activator for a number of lung-specific genes.
What are the official names of this protein?
Forkhead box protein F1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FREAC-1, Hepatocyte nuclear factor 3 forkhead homolog 8, HFH-8.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYSY_LACDB
Sequence: MANQDQAYLDLLKKIMTEGNDKNDRTGTGTRSLFGAQMRFDLSQGFPILTTKRVPFGLIKSELLWFLRGDTNIRFLLEHKNHIWDEWAFKNWVTSPEYQGPDMTDFGLRSQKDPGFKAVYDEEMQKFCQRILDDEAFAQKYGNLGDVYGAQWRHWGKRDGGFIDQIADVIEQIKTNPDSRRLIVTAWNPEDVPSSALPPCHVLFQFYVADGKLSLQLYQRSGDMFLGVPFNIASYSLLLSLIARETGLEVGEFVHTIGDAHIYKNHFAQVEEQLKRKPFDAPTLWLNPGKKKVADFEMADIKLVNYQHGSTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.