PharMolix/UniProtQA huggingface dataset:
Protein: YSCG_YEREN
Sequence: MKYKLNVLLAEIALIGTGNHCHEEANCIAEWLHLKGEEEAVQLIQLSSLMNRGDYASALQQGNKSTYPDLEPWLALCEYRLGLGNALESRLNRLATSQDPRIQTFVNGMKEQLKT
What are the official names of this protein?
Putative Yop proteins translocation protein G.
What is the protein family that this protein belongs to?
Belongs to the YscG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PROB_ALBFT
Sequence: MTKNFASVVLRDARRIVVKVGSSLVTNEGRGLDETAIGEWCRQIALLVQDKREVIMVSSGAVAEGMKRLGWATRPHLIHELQAAAAVGQMGLAQMYETKLRENGLGSAQVLLTHADLADRERYLNARSTLLTLLKLGVVPVINENDTVVNDEIKFGDNDTLGALVANLVEADALVILTDQKGLFTADPRKDSSATLVHEAKSGDPALEAMAGGAGSNLGRGGMITKILAAKRAAGSGASTVIAWGREPDALVRLSQGDAIGTLLVAQTQKTQARKQWIADHLQLRGSVTVDAGATQKLRGQGSSLLPIGMTTVDGDFSRGDVIAIRDLQGVEIARGLANYASVEARLICRKPSTEFEKLLGYAAEPEMVHRDNLVLTR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS52_VIBVY
Sequence: MKIVIIDYDMGNVRSIENAINHIGDYTIIVSGEPDTIRSADCLILPGVGAFPDAMKKLEQQKLIDLLTEEVVVRRKPVLGICLGMQLLFESSEEIQLTKGLGWIPGKVEYMRPGNDLRVPHVGWNSLILKKENSLFDYLQDDKDFYFVHSLWVNCPEKYKLATFEYGIEMTASVQYENIVGMQFHPEKSQRNGLEAIRSFLDWVKIQKLGVSHA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 2, IGP synthase glutaminase subunit 2, IGP synthase subunit HisH 2, ImGP synthase subunit HisH 2, IGPS subunit HisH 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_LEGPH
Sequence: MKSLVKAKKEPGIWMQDIPVPEYGVNDVLIKIKRTAICGTDIHIYSWDEWAQATIPVPMTVGHEFYGEIVEVGKEVQGLKVGQRVSGEGHITCGFCRNCRAGKRHLCRNTLGVGVNRPGCFAEYLALPATNVIALPDNITEEQAAILDPFGNAAHCALAFDVVGEDVLITGAGPIGIMAAAIVRHIGARHVVITDVNDHRLELARQMGVSRAVNVKYQKLSDVANELGMLEGFDVGLEMSGNPMALNDMMKAMNHGGHVALLGIPPQETPIDWNQVIFKGLVIKGIYGREMFETWYKMIAMLQSGLNISPVITHNFPVDEYQHAFQIMASGQSGKVILNW
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL1_CANLF
Sequence: MKTLLLTIGFSLIAILQAQDTPALGKDTVAVSGKWYLKAMTADQEVPEKPDSVTPMILKAQKGGNLEAKITMLTNGQCQNITVVLHKTSEPGKYTAYEGQRVVFIQPSPVRDHYILYCEGELHGRQIRMAKLLGRDPEQSQEALEDFREFSRAKGLNQEILELAQSETCSPGGQ
What are the official names of this protein?
Major allergen Can f 1, Allergen Dog 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR2_CERDE
Sequence: MTRRYWNINLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHIINLTRTARFLSEACDLVFDAASRGKHFLIVGTKNKAADLIASAARKARCHYVNKKWLGGMSTNWSTTETRLQKFRDLRAEQKTGRFNHLPKRDAAMFKRQLSHLQTYLGGIKYMTGLPDIVIIVDQQEEYTALRECVTLGIPTICLIDTNSDPDLADISIPANDDAIASIRLILNKLVFAICEGRSSYIRNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YOHD_ECOLI
Sequence: MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLVVLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFMYGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHLKHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA
What are the official names of this protein?
Inner membrane protein YohD.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y353_PYRHO
Sequence: MKLKGKGIGKVVVEGEVIVSRKPLSFLGGVDPETGTITDPESDIKGESITGKILVFPKGKGSTVGSYILYALSKNGKGPKAIIVEEAEPIVTAGAIISGIPLITNVDISKLKTGMRVRINPQEGEVEILAEGNL
What are the official names of this protein?
UPF0107 protein PH0353.
What is the protein family that this protein belongs to?
Belongs to the UPF0107 family.
Protein: THIG_STRAW
Sequence: MADDPFVLGDTPFSSRLIMGTGGAPSLDILERALVASGTELTTVAMRRVDAGVHGSVLSVLDRLGIRVLPNTAGCFTAGEAVLTARLAREALGTDLIKLEVIADERTLLPDPIELLDAAETLVDDGFTVLPYTNDDPVLARKLEDVGCAAVMPLGSPIGSGLGIRNPHNFQLIVEHARVPVILDAGAGTASDVALAMELGCAGVMLASAVTRAQEPVLMAEGMRHAVDAGRLAYRAGRIPRRHFAEASSPPEGRAHLDPERPAF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_YERPA
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLDSSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLTRIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIKAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: EIF3I_CANAL
Sequence: MRPIKLMGHERSLTQVKYNREGDLLFSVAKDNAASIWYSSNGERLGTLEGHQGVIWSIDVDPETHLCATGGGDLAIKLWKVENGQCVYTWDSPSPVRRVAFSPDGKKLLAIADQVMGHIGTVSVFDINDDDATLSQQKAEPSLVIETKSEGSKATVAGWSGDGDYIIVGHDNGYVSKYDSKTGKLVTSLQAHGIHNEEKNVSITDIQFAPEDRSYFITSSKDKTATLIDVDTFEILKVYKADAPMNTAAITPVKDFVILGGGQEARNVTTTAESQGKFEARFYHKIFEEEIGRVKGHFGPLNTVAVHPDGTGYSSGGEDGFIRVHTFDKSYQDFLFDAERTERAAAAGTI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRB_ECOK1
Sequence: MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLILLVIIQVLPLFLLMSITTGAIPAMLTGVMVACLPEKIGSQKRYRCLVGGIGGVVITEIYCAVIVHIKDMASSALFENILSGENLVVRIIPALLAGVVMSRIITHLPGLDISCPETDSLS
What are the official names of this protein?
Inner membrane protein CbrB.
What is the protein family that this protein belongs to?
Belongs to the CbrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCS_HAEIG
Sequence: MKLPIYLDYAATCPVDERVAKKMMAFLTIDGTFGNPASRSHKFGWQAEEAVDIARNQIADLIGADSREIVFTSGATESDNLAIKGAAHFYQTKGKHIITCKTEHKAVLDTCRQLEREGFEVTYLSPEADGLIDLEKFKAALRPDTILASIMHANNEIGVLQDIKAIGELCRANKTIFHVDATQSVGKVEINLEELAVDLMSMSSHKLYGPKGVGALYVRRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMASEMPRLKALRDRLYNGLKDIEETYVNGSMEHRLDSNLNISFNYVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFTLGRYTTEEEIDYTINLMKGAVEKLRALSPLWDMFKEGIDLNTIEWSAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_BREBN
Sequence: MSKVLFIKANDRPVEQATSVKLYEAFTKAYKETHPNDEIVELDLFAENLPYYGNDMLTAMWKAGNGIELSADEQKRADLVNKYLNQFTAADKVVFAFPMWNFTVPAVLHSYMDYLSQAGKTFKYTAEGPVGLMGDKKVALLSARGGVYSEGPMAQMEMANKYVRTILGFWGVNNVTEVIVEGHNQFQDKAAELVAAGVEKAVKLAESF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: DBH_RICFE
Sequence: MNKTEFIAFMTDHGHNHKHASHKTLTKADAEKALNLVLDSVISAIKSHHNINITGFGSFEIHHRKAREGRNPKTGAKMKIDAYNQPTFRAGRKMKEACN
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NCPP_YERPN
Sequence: MYHVIAATTNPAKINAITLAFDDVYGPGQYRIEGVNVDSGVPLQPIGSTETRIGARQRVKNARQVRPEADFWVGIEAGIEDNMTFAWMVVEHLQARGESRSASLMLPDIILQGIRQGRELGDEMAVLSGISNVKQQGGAIGIFTQGKLTRTSVYHQALLLALVPFHNEIYQRPSPSKPAI
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: PETD_CYAP4
Sequence: MAKVQKKPDLSDPKLKAMLKKGMGHNYYGEPAWPNDLLYIFPVVILGSIALCVGLAVLDPAMVGEPADPFATPLEILPEWYLYPVFQILRVVPNKLLGVVLMGSIPLGLMLVPFIENVNKFQNPFRRPVATTVFLFGTLFTLWLGIGATFPIDKSFTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: DABA1_SORC5
Sequence: MNSELSQDLGASAARQEHLRDVVEHAGHLLPAQGPIGVFVHHNTLHAFQHLPFHDALAAASAIFEAEPYLSEADYRAHIASGRIGDEDLEAALAGRFAAQPDERRGPLSRREIERLALRHPIEAETAAGLLWRISEAGETRRLRADVPDERRRRMVQSTERWLEARPEIAARLLDRAGRDPEARAALALWDACRAVPLPPAPPLEPPLVERVGEGRSHRDLLVELAGEDPAELIDPLMIRFLGAYLDEGIAHWTMPDRAKGLWRCFRDMALEGSRLAAPAFVGLDAELRRFDAEALSPPAIAVRALEELSVAEDHWDVYVTRVLLELPGWAGMIHRLEHTPSDRPPGSPPVSLVEYLAARLTLARYALRDVARRRLGYRGPLAGLVEHARRAARPPAPPSSSPDHARPFRLFQLAQLAGLSAAEIEPLSKAERVWALEALEAFDEITRRRVLHEAYEHHHRTEVLHGIAANLRRPEEERSVEAPRFQVAFCIDDRCEGLRRHFEELSPRHETFGVAGFFGVPIRYRGLDDAGHVSLCPVGVEPAHEIVERPHEEEAGWRRKARRKRWARFLHALGRGTRTLARGVLLTPTLGLLSTVPLVGRTLFPRAAARLRRALERRLLPPVPTRLHSPRDEGSAAGGEGQPFTAAAKAARVAATLENMGLTRGFAPIVVVLGHGATSVNNPHQSAYDCGACGGRHGGPNARLFAAMANDSEVRVLLAARGIDIPDGTFFLGGMNNTTTDEIVLYDQHLVPSSHRGELSALIGALDAARQQHAHERCRRFASAPREGDAARALAHVEARAADLSEARPELGHVTNAVCVVGRRSLTRGLFLDRRAFLVSYDPIQDQGGAILERVLLAVGPVGAGINLEYYFSCVDNRRYGAGTKLPHNLASLLGVMEGSLSDLRTGLPKQMIEIHEPVRLLVVVEASTDTAAALYARQPALRELIGNGWIQLACVDPATRRIACFTGDGFAPFSPPDQPLPAVQRSADWYAGRSGFVPPALIRAASTRPREVVDHAV
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: O165_CONMI
Sequence: MKLTCALIVTLLFLSITAGDSRGKHRYNALKSMSREANSTERECREKGQGCTNTALCCPGLECEGQSQGGLCVDN
What are the official names of this protein?
Conotoxin MiEr95.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_BURM7
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DHX33_DROME
Sequence: MDSKYFATSRNDAVGPSPVKFSFKRKYDAMANSPILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKTTQIPQFLLLAGYAKNGMIGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFEDVTSRATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVVVTSATMDIDHFGNYFNCKGMYLEGRTYPVRVMHTKEEHEDYIHTVLVTLFHIHRTTPKNHDVLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLRVFTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVLKSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQLLALDIDCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYPLDPKYSKLLLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEMAALAHAKFQSKHGDHLTLLNVFNGFLKSEKPKMWCHDNYLNLRSLTYARNVRRQLREISEHLHLALNSSDDIEMLKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYKPSYILFTEIVQTEQTFLRQVTEISIEWIKEVVPFVKNIPTR
What is the function of this protein?
Part of a translational control module, also containing pths/DDX47 and ais/DDX52, which coordinates germline stem cell differentiation with ribosome biogenesis during oogenesis.  This module allows for coregulation of ribosomal proteins and non1/GTPBP4, a p53 repressor, preventing p53 stabilization, cell cycle arrest and loss of stem cell differentiation.
What are the official names of this protein?
ATP-dependent RNA helicase DHX33, DEAH box protein 33 homolog, Protein athos.
Protein: KSHB_RHORH
Sequence: MTTVEVPHGSRSVILTVSAVVEETADTRSIVFAVPDELRDKFAYRPGQFLTLRIPSDRTGSVARCYSLASSPFTDDAPKVTVKRTSDGYGSNWLCDNIATGQTLEVLPPAGVFTPKSLDHDFLLFGAGSGITPVISILKSALTQGGGKVVLVYANRDEKSVIFAEELRALAEKYPTRLTVVHWLESVQGLPTADQLAAIAAPYESYEAFMCGPGPFMDTVHQALNTVGMPRARVHAEVFNSLSGDPFADQAPVEVSDEDAADAATVEVELDGEVHKLSWPRKQTLVDIMLAKGIDVPYSCQEGECGSCACTVLEGKVEMENCDVLDPEDIEAGYILGCQARPVTDHLKIEF
What is the function of this protein?
Probably involved in the degradation of cholesterol.  In vitro, catalyzes the introduction of a 9alpha-hydroxyl moiety into the ring B of 3-ketosteroid substrates such as 1,4-androstadiene-3,17-dione (ADD), 4-androstene-3,17-dione (AD), 4-androstene-17beta-ol-3-one (testosterone), 4-pregnene-3,20-dione (progesterone), 19-nor-4-androstene-3,17-dione (nordion), 1-(5alpha)-androstene-3,17-dione, 5alpha-androstane-3,17-dione and 5beta-androstane-3,17-dione.  KSH has the highest activity with 3-keto-Delta4 steroid substrates.
What are the official names of this protein?
3-ketosteroid-9-alpha-monooxygenase, ferredoxin reductase component, 3-ketosteroid-9-alpha-hydroxylase, ferredoxin reductase component, KSH, Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase, Rieske-type oxygenase, RO.
Protein: Y1696_SHEFN
Sequence: MELTSLEARVIGCLLEKELTTPDQYPLSLNSLALACNQKSSREPVLSLSESQVKTVLDDLTKKRLLSEQSGFGSRVVKYKHRFCNTEFSELQLSSAEVAIICVLLLRGPQTPGELKTRTNRLHEFADVSQVETALLALSQREKPLVVQLAREANKRDCRFLECFSGNVDDYDVNSSDAIVVSNHTQQTLQQDSKIVELEQRVKLLEQKLAQLESLLN
What are the official names of this protein?
UPF0502 protein Sfri_1696.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: SLU7_CAEEL
Sequence: MASYKQNLPPSALIKQQVNVADKKSKAEVQRDRQLEEDRKAGTAPAMVDVQTGRDINPHIPMFISQNPWYVPSEGPTLKHQRPHEEREKKMTQIHEWYQKGTTGKSATKFRKGACENCGAMGHQKRDCFDRPRKSNAKETNDNIAEDDYVQPNLTLGFDAKRDRWNGYDPSTHKQVIEDYEHLEEARKVVREHEMKEGEVEPATTEDGAPKDEDMYAEDADMAGVSVDMDSRTRITVRNLRIREDTAKYLYNLAENSPYYDPKSRSMRENPFAGVAGKELEAARFSGDNFVRYSGEVTAANEAQVFAWQATRGGVYAHSIAEPTKLEALKKEYEKEKSTLKNETQKELLDKYGGGEHMERPADELLLAQTESYIEYNRKGKVIKGKEKVAISSRFKEDIYPQNHTSVFGSFWREGRWGYKCCHQFVKNSYCTGKQGIEAETSAAKGTTTSNEEIFKVPKLVEKTEVKEEKEKEDSIKDEVAEENSDNDNDEEKEKVSEKSISPSPPSDDEEKEKEREKERLIEKERRERDQRRRDKKREKRERKKAKLGKRKRRHRDSDDESDPSSGSGSESDSDEEMRKAMKKAKREKAEGMKAAREGDRGRKYNTDYSNTAPNEKEMEAYRVTSVHSADPMAAYMNSKFEKKHTK
What is the function of this protein?
Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMC1_HUMAN
Sequence: MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWEITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYSYGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDPSSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHYALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKSSSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKGPVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPDVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176, PubMed:32439656).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231).  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
What are the official names of this protein?
ER membrane protein complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the EMC1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: HCHA_ECOUT
Sequence: MTVQKSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESEDVAAALQWAIENDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_CORK4
Sequence: MAVKKLADLLKEGVEGRHVLVRADLNVPLKDKVITDPGRIDASLPTIKALTEAGARVIVAAHLGRPKSPQDTQFSLAPVAEALSQRLDQYVALASDVSGEDAHERANGLNDGDVLLLENVRFDPREKSKNDAEREELASELAALTGDNGAFVSDGFGVVHRKQASVYDVAKKLPAYVGYLVEKELEQLSKCTDDPQHPYAVCLGGSKVSDKLGVIKALAPKVDTLIIGGGMCYTFLKAKGYGVGDSLLEESMIDECKNLLSEYSDKIVLPSDIVVGKEFDANTEHKTVSADGIEDGWMGLDTGAESIKTFGERLNGAKTIFWNGPVGVFEFEAFANGTKGLAEAIAEATKNGAFSVIGGGDSASAVRNLGFADEAFSHISTGGGASLELIEGKTLPGVAVLDR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y306_CALS4
Sequence: MLDLYIEEIYKRIEKIKSTQLEKIKQAAHLITESLISEDSVFHVFGCGHSHMAAEELFYRAGGLACVNAILPSELMLHEGALKSSYYERNEEIIKLIFDRYELRKGECIIIVSHSGRNGAPVEAAIDAKRRGLHVVALTSTEYKQKTFSRHSSGKFLEDVADIVIDNCGPYGDAVLTVEKEDIKISFSPLSTVLNTVILNMLEAEIITNMLEKNMSPPVFLSGNIEGAEEHNLKLIEKYKKRLRHL
What are the official names of this protein?
UPF0309 protein TTE0306.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: F167B_MOUSE
Sequence: MSLGPLKFQAVGEKGEEDEEESLDSLKALTAKLQLQTRRPSYLEWTARVQSRAWYRAQARPEPVGPGAICGFDSMDSALEWLRRELQEMRAQDRQLAGQLLRLRARLHRLKVDQVCHLHQELLDEAELEMELESGTGLPLAPPLRHLGLTRMNISARRFTLC
What are the official names of this protein?
Protein FAM167B, Protein SEC.
What is the protein family that this protein belongs to?
Belongs to the FAM167 (SEC) family.