PharMolix/UniProtQA huggingface dataset:
Protein: NRX3A_HUMAN
Sequence: MSSTLHSVFFTLKVSILLGSLLGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSTGLLLYLDDGGVCDFLCLSLVDGRVQLRFSMDCAETAVLSNKQVNDSSWHFLMVSRDRLRTVLMLDGEGQSGELQPQRPYMDVVSDLFLGGVPTDIRPSALTLDGVQAMPGFKGLILDLKYGNSEPRLLGSRGVQMDAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGKLCSEDVSQDPGLSHLMMSEQAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTTGGELVIPLLVEDPLATPPIATRAPSITLPPTFRPLLTIIETTKDSLSMTSEAGLPCLSDQGSDGCDDDGLVISGYGSGETFDSNLPPTDDEDFYTTFSLVTDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRDLKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDREYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling (By similarity).
What are the official names of this protein?
Neurexin-3, Neurexin III-alpha, Neurexin-3-alpha.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RPOC2_PROM3
Sequence: MTSTSPKSRKPSTKTTKSKSKSKSKSKAAKAAAASASPALARTPPQFRNRVVDKKALKQLVAWAYKTHGTAVTASMADNLKDLGFRYATQAAVSISVEDLKVPEAKQDLLCQAEAQITATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKKNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREDDCGTTRGIIVKVEDGGFGSRLVGRLTADQVVNVDGEILAERNTEIDPPLSKRFEKAAITEVMVRSPLTCEANRSVCRKCYGWALAHNELADLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAETGVVRSTVAGTVEFGPKARVRGYRTPHGLEAQQSEVDFTLTVKPSGKGRAQRIDITTGSLLFVSDGQEIEADVTVVQIASVAVKKSVEKATKDVICDLAGQVRYEQVIQPREVKDRQGNITLKAQRLGRLWVLAGDVYNLPPNAEPVVQGNVKVERGQVLAEASQASEFGGEVRLRDSIGDSREVQIVTTSMTMKDFKLLGESTHSGELWHLEAKEGTRYRLNTIPGSKIGNGEVVAELADDRFRTQTGGLVRFAPGLAIKKARSAKNGFEVNKGGTLLWIPQETHEINKDISLLMIEDGQWIEAGTEVVKDIFSQTAGIVTVTQKNDILREIIVRSGSFHLCAETKALERFRGDGQIVNPGETIAKGINSEAMVFVQTEDTPEGTGLLLRPVEEYTIPNEAHLPELTHVKQPKGPHLGIKATQRLAFKDGELIKSVEGVELLKTQLILETFDTTPQMTVDVEAVRDKRAKTIERLRLVILESILVRRDTISDSSHGSTHTELQIEDGQSVKASDVVATTQILCKQEGIAQLPVPQEGDPVRRLIVERDEDTITVTTKGSPLVGVGQRLVDGDSLAKDEPSSCCGEVEEVEGKAITLRLGRPYMVSPDSVLHVRDGDLVQRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRESAVLCKKPGTVEIKQGEDDESITVTVIEADDAIGEYPILLGRNVMVSNGQQVHAGELLTDGPINPHELLDCFFEDLRGRKPLMDAAQEAIAKLQHRLVTEVQNVYKSQGVSIDDKHIEVIVRQMTSKVRIEDAGDTTLLPGELIELRQVEDTNQAMAITGGAPSEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFQEELRAEAGPHPDILAEDPAGYRRMQNLRPDYTVDMPAAPAASSTAVLADPSAADLEATRSRHGIDPAASNFAAFVRPTGENELEEEQLPDPSALEGLQQEGLLTEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: DNLJ_DESVM
Sequence: MSISDDISPVPPAPVSEPNAGQDAGQDAAPAHMAARAEALRDQLNYHSHRYYVLDDAEISDAEYDALFRELQDIEAEWPSLRTPDSPTHRVGDTVVAALETQAHTLRMYSLDNAFSAEEWDGFIQRMLRAEPDAPTAFWCDPKMDGLALEVIYENGVFTTALTRGDGEKGEIVTTAMRTVRNLPLRLHGEGPHPARLEVRGEVVITRAEFDALNAARRGAGEKLFANPRNAAAGSVRQLDASVTAGRPLRFLAYGVGQVVWPAETSDGAASAAQGPEARWATHGQVMAALADYGFGTPPDARRCETPAQVMAYYEDLGRRRSELPFDIDGVVAKLDDLSAQAALGYTARAPRWAIALKFPAHQATTRLEHIAIQVGRTGVLTPVAELAPVAVGGVTVSRATLHNEDEIRAKDLRVGDMVVVQRAGDVIPEVVRPLVDQRPASGLPEFEFPAECPVCHTPVRREPGEAAWRCVNVGCPAVVRQSIIHFVSKAGLDIQGVGRRWVELLVDRGKVTSPADLFGLDKQTLLAFERMGPKLAENFIAAFDTARTGATLNRLICALGIRHVGEQTARTLAAHFADLDALGAAQAETLQQLPDIGPEVAASIRAFFANEGNRALLERLRGVGLWPVRPVRPEADAAGAPGEGSGPLAGLRVLFTGSLTTLTRSDAERRAVAAGANILGSVSKKLDLLVVGDKPGSKLDKATKLGIRVLREQEFLDLLEGRGGDVPEDGDGAPGNEDEAPEVSADVPAAPEVLADAPAAISADASSGVAPGVSGGPDRADMTDRTVRTDSVDAPAMPRKKDQHSLL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MTBB1_METBA
Sequence: MATEYALRMGDGKRVYLTKEKIVSEIEAGTADAADLGEIPALSANEMDKLAEILMMPGKTVSVEQGMEIPVTHDIGTIRLDGDQGNSGVGIPSSRLVGCMTHERAFGADTMELGHIDYSFKPVKPVVSNECQAMEVCQQNMVIPLFYGAMPNMGLYYTPDGPFENPGDLMKAFKIQEAWESMEHAAEHLTRDTVWVMQKLFASGADGVNFDTTGAAGDGDMYGTLHAIEALRKEFPDMYIEAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLVAKAGANVFGPVCNTNTSKTSAWNLARAVTFMKAAVEASPIPCHVDMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGIOIGVGDPLGMPIAHIMASGMTGMRAAGDLVARMEFSKNMRIGEAKEYVAKKLGVDKMDLVDEHVMRELREELDIGIITSVPGAAKGIAAKMNIEKLLDIKINSCNLFRKQIA
What is the function of this protein?
Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC (PubMed:10852929).  The major or perhaps only DMA methyltransferase expressed under inducing conditions (PubMed:16096277).
What are the official names of this protein?
Dimethylamine methyltransferase MtbB1, DMA methyltransferase 1, DMAMT 1, Dimethylamine--corrinoid protein methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the dimethylamine methyltransferase family.
Protein: VATL_BETVU
Sequence: MSTVFNGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAD
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit, V-ATPase 16 kDa proteolipid subunit, Vacuolar proton pump 16 kDa proteolipid subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: COX2_EENNA
Sequence: MREMMMNNMLNDVPTPWAMYFQDSATPNMEGMMELHNNVLFYLCVMLGFVTYMLYNVMTVYNKSAMAYKYMNHGQFMEMMWTTFPAMMLLMMAFPSFMLLYMCDEVMAPAMTIKAMGLQWYWKYEYSDFMVEKGETMEFESYMIPEDLLEDGQLRMLDVDASVVCPVDTHMRFMVTSADVIHDFCMPSLGIKIDAAPGRLNQTSALMQREGVYYGQCSELCGVMHSSMPIKIEAVPTVDFLAWIDEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FB263_ARATH
Sequence: MAMSDLPNDLVEEIISRVPVKSIRAVSSTCKNWNTLSNDHSFTRKLFGKTITTKENECLVVMMMDSKVYLMSVNLHRIHKENDDNNIKSSIMHKAKLISLNDDDILNNTYIIFHCNGLLLLLGFTDDGIKLVVTNPHLGQTRWIKPRKANYQFCDKYAIGYEKKKNNSLRTNKMLLFHKESFCFRIYWFEIYNFNSASWNVFYFTRDWELPYSQGVSLKGNTYWFAREINIRGERIDDPPDFLICFDFTTERFGPRLHLPFHSHSDDTVILSSVREEQLAVLIKRFDLWRMEIWVTTKIEPKEVSWNKLFLAVDMIPLITAFQFCNVSFFIDEKKNVVVVLGKDVLNTRNIANIIGNDGYFKQVDLGESTNKYCYPLVCSYVPSSVQIKQATRVMHHHHIVLRAVVRAVRDSDRERKLNNGREHKISRRTRIHERILFRMLKLDEEAIGIRSRSVPRDRYQQGFASSPCRA
What are the official names of this protein?
Putative F-box protein At5g36200.
Protein: PRS37_MACFA
Sequence: MKFIFYLSVLTGTFLFADSSVQKEDPAPYLVYLKSHFNPCVGVLIKPSWVLAPAHCYLPNLEVMLGNFKSRVRDGTEQTINPIQIVRYWNYSDSAPQDDLMLIKLAKPAMLNPKVQPLPLATTNVRPGTVCLLSGLDWSQENSGRHPDLRQNLEAPVMSDKECQKTEQGKSHRNSLCVKFVKVFSRIFGEVAVATVICKDKLQGIEVGHFMGGDVGIYTNVYKYVSWIENTAKDK
What is the function of this protein?
Plays a role in male fertility.  May have a role in sperm migration or binding to zona-intact eggs.  Involved in the activation of the proacrosin/acrosin system.
What are the official names of this protein?
Probable inactive serine protease 37, Probable inactive trypsin-X2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted.
Protein: RPOC_ACTPJ
Sequence: MKDLVKFLKAQSKSNDDFDVIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELACPVAHIWFLKSLPSRIGLILDMPLRDIERVLYFESYVVTEPGMTDLEKNQLLTEEQFLDAEERWGDEFEAKMGAEGIQALLRDMDLEHQCEMMREELQETNSETKRKKITKRLKLLEAFQQSGNKPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQKSVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLHLHQCGLPKKMALELFRPFIYSKLESRGIASTIKAAKKMVEREEPIVWDILAEVIREHPILLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTREKVNAKGEGMYFLDPREAEKAYRTGQAELHARVKVRITEHVKNEAGELVAETKLLDTTIGRAILWMIAPKGMPFKVFNQTLGKKAISKLINESYRRLGLKESVILADQIMYTGFAYAARSGASVGIDDMVIPAQKHEIIRAAEAEVAEIQEQFNSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEEVINREGNPEKQASFNSIFMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVITEDDCGTHEGIVMTPLIEGGDVKEALRDRVLGRVVAEDVLKPGTEEVLIPRNTLIDEKWCDVIDAESVDVIKVRSVVTCNTDFGVCAKCYGRDLARGHLINQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASAAAKESSIQVKNAGTIKLTNAKFVTNKEGKIVLTSRNTELTVIDTFGRTKENYKVPYGAVLSKNDGAEVAVGEVVANWDPHTMPVISEVSGRIQFSDIVDGLTVTRQTDELTGLSSIVVQDVGERATAGKDLRPALRLVDAQGNDILIPGTDVAAQYFLPGKAIVTLDDGAEIEVGEALARIPQESVGTKDITGGLPRVADLFEARKPKEPAILAEISGIVSFGKETKGKRRLVITPAEGEAFEEMIPKWRQLNVFEGEMVQRGDVISDGAETPHDILRLRGVHAVTDYIVNEVQEVYRLQGVKINDKHIEVIVRQMLRKAVITNAYDSEFLEGEQVEVSRVKIANRKRAEEGKPLVEFERELLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGFAYHQARAKKRSQPEQAVAFEAPVAKANGFATDADIEAEFEFVADDATQSLAALLNAGDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RPOZ_STRPG
Sequence: MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MDTJ_SALNS
Sequence: MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKEATRATI
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSTX3_HAESL
Sequence: MRTLLVFLLLAILVAVLIGNVQVEACKQGIDCKYPRGCIEGVCEPLYG
What is the function of this protein?
Leech salivary gland peptide with unknown function.
What are the official names of this protein?
Peptide HSTX-III.
What is the protein family that this protein belongs to?
Belongs to the annelide toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_SULIA
Sequence: MIQIFFLGTGAGSPSKKRKLPAFLVRREGLNILLDCGEGTQYTLMNNKLGINSIKIIGITHMHGDHVFGLLGVIASMGLLDRKETLYILGPRDLKDFLYTSFEYSKFNPSFKIEFIDNYNDQNITIATFKTCHTVESQGYLISERDRVKIDEEKLEKEKIKDWRVMRKLKEGKTVEYNGKFLKPEDYLVIKRGLKVAYTGDTIPCQSVIESVKGVDLLIHDSTFLNEPSACTYGHSNVADAAKVALEASVKLLALTHISPRYEDVTEHLKVARRIFPKSILPDDLSYITLK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: FBL17_ARATH
Sequence: MQPQPHISPNTATAAISAALESQRSRKNRGSYNCGRCGQPKKGHVCLLTAPPDIPTTPIASEPVSCISAAASSSRSTVLSLTAAPSSRQTFTHLRRALSFDDVDARNSLDESDLDAASMDLDLQLDTDIVQPGRFHAVGLWEVLKRLPPSSLLMAARVCKGWRETSRKMWKAAEELRIRVPERAQIGYIGSLLQKCPRLIRLSLKIESDFDATTLACIAFSCPNLEVLEITTSGAAVNRISGDELSRFVANKRGLTSLKMEGCSNLGGFSLSSSSLSTLWLSDLHSLSKMIFNCPNLTEISLEFSRQEDDSTDLVTMVDGLGRTCTRLQNIHIASLKLSHTVVLSLTAVNFRYLRMLSLVLGINITDASVAAISSGYKNLELLDLSGSSITDTGLGMICDVLPDTLSKLLVALCPNITSSGIQFATAQLPLLELMDCGMTVSDPNSDNPTFVENPSPHKTPGYNQKMFIKHKRLKKLSLWGCSSLDALFLNCPELMDLNLNLCSNLHPESLVLQCPKLQLVYASGCQGLLTGAIRKQVSENFSAGENHMPRKRLADASKRIQALPSLYQETREDGIYAGKRRKLEKEMCTIIH
What is the function of this protein?
Essential protein for male fertility.  Component of the SCF(ASK-cullin-F-box) E3 ubiquitin ligase complex SCF(FBL17), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Enables the switch in cell cycle control leading to male germ cell lineage formation from microspores after meiosis.  Targets CDKA-1 inhibitors the degradation specifically in male germ cells (e. g.  KRP6 and KRP7) and thus enables CDKA-1 activation and germ cell S-phase progression.  Promotes twin sperm cell production and double fertilization.
What are the official names of this protein?
F-box/LRR-repeat protein 17, F-box-like protein 17.
What are the subcellular locations of this protein?
Nucleus. Note=Confined to the male germ cell nucleus of early to mid bicellular pollen.
Protein: RS14_EHRRW
Sequence: MSRKSVIQRNLKRISICDRLKSKREKLRAIIKDQSISMNDRFLAQVKLSKLPRDSSYIRIRNRCLITGRPRGCYRKFKVSRIVLRQLGSIGQIPGLTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RUVA_CHLSY
Sequence: MIASIRGIIQSIGIDHLIVETGGVGLLIYAPRSTLNAVGQIGSETFLYTLLIVREDALTLYGFSDPAQRNLFEQLIGVSGVGPKIALNLLSSGSPDEIQKSIAGGDIARLARVPGIGKKTAERIVLELRGKIDLRQLSGTTPGNVSTLDRELTDILISLGYSATEAAAAIAALPGDAPPTLEERLRLALRYFGSA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FLHC_ECOL6
Sequence: MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG1_CANAL
Sequence: MIPQSNPTAQRRSGDAQNTNNVAPNSVATTTDTALTASTQSGSSSNNANKKLEYIGVYKIGPEIGKGSFATVYKCIDTTNNKAVAIKSVYRSKLKSKKLLENLEIEIQILKSMKHPHIVGLLDYKQTTSYFHLVMDYCSMGDLSYFIRRRNNLVKSHPVISSLLHCYPSPEGSHGLNEVLVLHFLRQLSSALQFLRDKSLVHRDIKPQNLLLCPPVHSKQEFIDGEFVGMWELPILKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVLYEMTVGKPPFKAGNHIELLKNIEKANDKIKFPSAAQVPEPLKQLIRSLLKYNPTERISFNEFFNDSLITCDLDDNDQPLETSQMDENLFISEYISPIAPAERSQFFKEQKKNDSVVRSPSPTTATTATPRQDNVVQQMTKITSPVPDDFALSIARNSSEFNLKKDDMNLEKDYVVVEKRAVEVNALADELAHAGAGADAIPNSRKNSDVDQTNRLASSQQQTETASYRRSSSSGSQKRPSFSERRISLSLSPTNALTKAIGLASNRLFGLTTNSSHSNVSAIAEDDDSSTSNNDASSFSTVIPSTNNHVLLQKLNLATIGEPGTEFDLGSVSNLDEQILDKLELIANIANAVNLYADVKFSQIIPSPPSSDGIEDDTEMLPPKIIHMISQEGIGLYIKTLSLLGRAMDIAGQWWFEKYDAVHGERPSFETTVRINQIVQWIREKYNISLERLEFLKSKSDFTAEETIEDNEPNGTTRVQQAIFAAALGIARETALKELLRNSTDIECSYVTSIYMLLAILEDLEESDRQEVKKIIEKINSRLKNFMGK
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: YNJI_ECOLI
Sequence: MKKVLLQNHPGSEKYSFNGWEIFNSNFERMIKENKAMLLCKWGFYLTCVVAVMFVFAAITSNGLNERGLITAGCSFLYLLIMMGLIVRAGFKAKKEQLHYYQAKGIEPLSIEKLQALQLIAPYRFYHKQWSETLEFWPRKPEPGKDTFQYHVLPFDSIDIISKRRESLEDQWGIEDSESYCALMEHFLSGDHGANTFKANMEEAPEQVIALLNKFAVFPSDYISDCANHSSGKSSAKLIWAAELSWMISISSTAFQNGTIEEELAWHYIMLASRKAHELFESEEDYQKNSQMGFLYWHICCYRRKLTDAELEACYRYDKQFWEHYSKKCRWPIRNVPWGASSVKYS
What are the official names of this protein?
Inner membrane protein YnjI.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP5_APRVF
Sequence: MIDLRLEEDILTATLPEFLTTRPKYRYAYTNTKQQDLRLLGPMRHVRLTHLYKHTKLWNLQYIERELTNIEIDDALDEFMQTFSLPYTIEQGTYKYNMLLGMHAHNIGYQDDVSELIANNPQLLNYLNDNPLASIFELIDIDLQIYQYGQNIFNNEVEHMILFLKDNTYHGVIQALQKHPFSATHVTWHLHKHIFVFHSREKLLNKLLATGLEDSQLYQRQKTYSTKRGDRPTERMITYIEDDHIRRIQAVLPLLLDNIFDVKLHRDSSMTWLKSYADTIYDSAKNSDSTVTPEIRKLYLRMYNQYMRVFLPIEQYMLYDTTCWPFSEKITLKINVRLISSRENQPVSWKTPIDTENLISIVQPDNPINKLNFTAVPSTMIRLNDNIMMYRSVKDMFAAIEYIPDSDENIPTIEMKEQALSRYISPDSEAQNFFNNQPPYLNSIINVNKQVFEAVRRGNIQVSTGSAEHLCLCMYVKSGLIVGRTVLIDDKVILRRNFNASTAKMITCYVKAVTQLYGEGSLIYPGLRIVFFGVETEPAMDVLKLFYGDKALYIQGFGDRGIGRDRFRTKIEDALTLRIGCDILISDIDQADYQDPSEEKFDDITEFVCYLTELVISNATIGLVKISMPTYYLLNKISQNINNKFSKVNINIVKLSTQKPYTYEAYLLLSHGSTLTTKGYAKNPVCDVYLEQISLQPQEIKIISTISNEINYDKPTLYRLVVDKNDITDVSIAMHILSIHCSTIITRSVMVKNDNTGAFVTMSGMKDMKRVAIMNRMTDGTNENAYMYEDNGKLYLQKVPYLEDLVNAFPNGFGSTHQNDYDSSTSVINVNALVRQVVYRVISKSIPVALLESLSRIRIVGGRDLGEMNAVYKLYKTPVEVYDTVGITREYPHVQISYRAQRYQFTESIPNHTLLLANYVIMNDIDRAPISSAEQINTIKKIISKIGVGSIAYVQVYTDVVARHINVMTKNDSFLISANADKTVFKVQVSGYKAVEMCNYEQLLQLVSDNTGVHIIKLTYQDVLESCVLSSGILGDTGSWLLDLVLASTYIIEIRG
What is the function of this protein?
Outer capsid protein involved in mRNA capping.  Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities (By similarity).
What are the official names of this protein?
Outer capsid protein VP5.
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus lambda-2 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CYAY_PECAS
Sequence: MNDSEFHQLADELMLQLEETLDQFEGDADIDSEINGGVMTLSFENGSKIVINRQEPLHQIWLATKTGGYHFTLREERWVCDRSGEDFIALLSSACSAQAGETVHFE
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: LEXA_VIBC1
Sequence: MKPLTPRQQQVFDLIKSKIEDTGMPPTRAEIARELGFRSANAAEEHLKALARKQAIEIIPGASRGIRILLEDAANDDQGLPLIGQVAAGEPILAQEHVESHYQVDPAMFKPKADFLLRVNGESMKDIGIMDGDLLAVHKTQDVRDGQVVVARVDDDVTVKRLERKGSTVLLHAENEEFSPIQVDLTSQHLTIEGLAVGIIRNTDWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.