PharMolix/UniProtQA huggingface dataset:
Protein: TRMD_BACC7
Sequence: MKIDILTLFPDMFTGVFGSSILKKAQEKEAVELRVVNFRDYTTSKHNSVDDYPYGGGAGMVLTPQPIFDAVEDLTKETERKPRVVLMCPQGERFTQKKAEELAEEEHLIFVCGHYEGYDERIREHLVTDEISIGDYVLTGGELASMVITDSVVRLLPGVLGNHASQVEDSFSTGLLEHPHYTRPADFRGMKVPDVLMSGNHKNIDEWRHKESLRRTYTRRPDLLEERELSKQEKKWLEQIKEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_ECOBW
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLI3_NEUCR
Sequence: MSGQGFSNADTGNKPADPYKQANLDTEVPLDQKINDLSSFMTSNKFSMMTTRDSKTGYLLSRCMALAATESGGIDLLFHTNTESGKTDDLKSDEHINISFLNSTTGDWASVSGTASIVTDRDLVRKHYNPHLKAWFGDLGDGVHDGGPEDPRVGVIRVKMVTAHYAISTKNIVGKVADVAQGVITGKPATVNKLREISEQEVQSWRSSH
What are the official names of this protein?
Protein bli-3.
Protein: NIFU1_ARATH
Sequence: MMASLATSISGSFRILVKSSSTRNGFPVISDQNPSFVLFANKRRHISRTAIFHRSAISGSSQGEKISPLASGVSSGLYSAQTFDLTPQNVDLVLEDVRPFLISDGGNVDVVSVEDGVVSLKLQGACTSCPSSSTTMTMGIERVLKEKFGDALKDIRQVFDEEVKQITVEAVNAHLDILRPAIKNYGGSVEVLSVEGEDCVVKYVGPESIGMGIQAAIKEKFKDISNVTFTS
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of chloroplastic iron-sulfur proteins.
What are the official names of this protein?
NifU-like protein 1, chloroplastic, AtCNfu1, AtCnfU-IVb.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TRHO_CROS8
Sequence: MPVLHNRISNEELRARMLAETEPRTTISFYKYFTIDDPKATRDALWQAFTALNVFGRIYLAHEGINAQISVPESNVEAFRAALYGFHPALDGVRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPTFDASDVGEYLKAAEVNAMLDDPDAVFIDMRNHYEYEVGHFENALEIPADTFRAQLPKAVEMMQEYKDKKIVMYCTGGIRCEKASAFMRHNGFQKVWHIEGGIIEYARKAREQGLPVRFVGKNFVFDERMGERISDDVIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPACAEKFSGCCSELCKEEMSLPEEEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: SECA_STRGC
Sequence: MANILRTIIENDKGELRKLEKMANKVIAYSDQMAALSDEELKAKTDEFKQRYQNGESLDDLLYEAFAVVREGAKRVLGLYPYPVQIMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALAGEGVHVVTVNEYLTERDATEMGELYSWLGLSVGINLAAKSPAEKREAYACDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGPVSSETNQLYHMADSFVKSLNKDDYIIDVPSKTIGLSDSGIDKAESYFKLDNLYDIENVALTHFIDNALRANYIMILDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPVQDETKTSASITYQNLFRMYKKLSGMTGTAKTEEEEFRETYNIRVIPIPTNRPIARIDHEDLLYPSLESKFKAVVEDVKERHLKGQPVLVGTVAVETSDYLSKKLVAAGIPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSERIKAVLDRFKLSEEESVIKSKMFTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERHDVITANRDLAPEIHAMIKRTIDRFVDGNSRAPQEEKLDSILYFAKYNLVPEESISLSDLQGLSDEEIKASLYERALEVYNSQIAKLRDEEAVREFQKVLILRVVDNKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQSESFRMFNDMIGSIEFDVTRLMMKAQIHEQERPRTEHNIVTTATRNISAQESDLPADVDLAKVGRNELCPCGSGKKFKNCHGRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CATC_HUMAN
Sequence: MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL
What is the function of this protein?
Thiol protease (PubMed:1586157).  Has dipeptidylpeptidase activity (PubMed:1586157).  Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids (PubMed:1586157).  Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1586157).  Can act as both an exopeptidase and endopeptidase (PubMed:1586157).  Activates serine proteases such as elastase, cathepsin G and granzymes A and B (PubMed:8428921).
What are the official names of this protein?
Dipeptidyl peptidase 1, Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, DPP-I, DPPI, Dipeptidyl transferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PSMF1_RAT
Sequence: MAGLEVLFASAAPAMTCPQDALVCFLHWEVVTNGYYGLGTGDQPDPNDKKSELLPAEWNSNKELYALRYESKDGARKLLLKAVSVENGMIINVLEHGTQQVADLTLNLDDYIDAEDLSDFHRTYKNSEELRSRIRSGIITPIHEQWEKVRLSSPPREFPPATAREVDPLRISSHHPHTSRQPTWRDPLSPFAVGGEDLDPFGCQRGGMIVDPLRSGFPRALIDPSSGLPNRLPPGAVPPGARFDPFGPIGTSPSGPNPDHLPPPGYDDMYL
What is the function of this protein?
Plays an important role in control of proteasome function.  Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome.  Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28 (By similarity).
What are the official names of this protein?
Proteasome inhibitor PI31 subunit.
What is the protein family that this protein belongs to?
Belongs to the proteasome inhibitor PI31 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: DPP5_ARTOT
Sequence: MAPAKWLIASLAFASTGLAFTPEDFISAPRRGEAIPDPKGQFAVFPVSKYNFDTKDRPSGWNLLNLKTGDISVLTTDADVSEITWLGEGTNLLYVNGTDSVKGGVGIWISDAKNFGNAYKAGSIPGAFQGFKLAKSGDKINFVGYGQSTTKGDLYNEAAIEKPVSSARIYDSLFVRHWDAYVGTQFNAVFSGALTKNGNKYSFDGKLKNLVQPVKYAESPYPPFGGSGDYDLSPDGKTVAFMSKAPELPKANLTTSYIFTVPHDGSKVAEPINKRNGPRTPHGIEGASSSPVFSPDSKRIAYLQMATKNYESDRRVIHIAEVGSNKPAQRIASNWDRSPESIKWSSDGRTLYVTAEEHATGKLFTLPSDARDNHMPSAVKHDGSVSAFSFVGSSKSVLITGNSLWSNALYQIATPGRPNRKLFYANEHDPQLKGLGPNDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPLAFLIHGGPQGSWGDNWSTRWNPRVWADQGYVVIAPNPTGSTGFGQKLTDDITNDWGGAPYKDLFKIWEHVRDNLKYVDTDNGIAAGASFGGFMINWIQGQELGRKFKALVSHDGTFVGSSKIGTDELFFIEHDFNGTFFEARQNYDRWDCSKPEYVAKWSTPQLVVHSDYDFRLSVAEGVGLFNVLQEKGVPSRLLNFPDESHCVTKPENSLVWHQQVLGWINKFSGINKSNPKAIKLSDCKVEVIDHEAGSYFDY
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini.  Contributes to pathogenicity (By similarity).
What are the official names of this protein?
Dipeptidyl-peptidase 5, Dipeptidyl-peptidase V, DPP V, DppV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS181_SACEN
Sequence: MRNEQRRGGQRRGKPNLLQRAGVVQVDWKDTDLLRRFISDRGKIRSRRVTGLTMQEQREVATAIKNAREMALLPYPAAAKR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RHAR_ECOUT
Sequence: MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_ECOBW
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_STRFR
Sequence: MSRRLFTSESVTEGHPDKIADRISDTVLDALLARDPRARVAVETLITTGQVHIAGEVTTTAYAPIAQLVRDTVLSIGYDSSAKGFDGASCGVSVSIGAQSPDIARGVDTAYERRGGGTAPGGPGDELDRQGAGDQGLMFGYACDETPELMPLPINLAHRLSRRLSEVRKNGTIPYLRPDGKTQVTIEYDGDKAVRLDTVVVSSQHASGIDLDSLLAPDIRRHVVEPVLAGLAEDGIKLDTAGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLASRCEVQVAYAIGKAEPVGLFVETFGTATVDVERIEQAIGEVFDLRPAAIIRDLDLLRPIYAKTAAYGHFGRELPEFTWERTDRTEQLIAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIM_CAUVN
Sequence: MADELDDQAAMAQWASENPPGGGEGVNEFGDFSGGMGGWDDGGGDGASERILNQDEIDSLLGFDLSGDGSDDRTGIRAIINSALVSYERLPMLEIVFDRLVRLMTTSLRNFTSDNVEVSLDNISSIRFGDYLNSIPLPAILAVFRAEELDNYGLLTVDSNLIYSIVDVLLGGRRGTAAMRIEGRPYTTIERVLVQRMIEVVLHDLKSAFEPLHPVSFSLDRLETNPRFAAIARPANAAILVKLRIDMEDRGGRIELLLPYATLEPIRKMLLQQFMGEKFGRDNIWEGHLATELWTTQMEVRAVLDEQQVPLSRVLNMQVGDTLMLNATPDSLVELRAGAIPLTRGRMGRRNHSIAVRAEAPLTPAAKKAVQKLK
What is the function of this protein?
FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliM.
What is the protein family that this protein belongs to?
Belongs to the FliM family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Protein: SYH_ACIBC
Sequence: MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQKGRYRQFHQFGVETFGVATPDIEAEVILMTARLWKRMGVAHMVQLELNTLGEKEERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLYDFLKEDSLSHFQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCGGGRYDGLVGQLKGKADQSVPAVGFGMGMERLLLLIEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBT11_MOUSE
Sequence: MSSEESYRAILRYLTNEREPYAPGTEGNVKRKIRKAAACYVVRGGTLYYQRRQRHRKTFAELEVVLQPERRQGLIEAAHLGPGGTHHTRHQTWHDLSKTYWWRGILKQVKDYIKQCSKCQEKLDRSRPISDASEMLEELGLDLDSGEESNESEDDLSNFTSPPSTASKSSKKKPVSKHELVFVDTKGVVKRSSPKHCQAVLKQLNEQRLSNQFCDVTLLIEGEEYKAHKSVLSANSEYFRDLFIEKGAVSSHEAVVDLSGFCKASFLPLLEFAYTSVLSFDFCSMADVAVLARHLFMSEVLEICESVHKLMEEKQLTVYKKGEVQTVASTQDLAAHNGTTTPPGTRNEATTTLSGELGHCEIVLLVNGELPEAEQNGEPEQQPAPQASPEAEASVSPVEGIPEPHPEMGTASLAKESNQPESAVTREDGIVASVHPKISKENVTNASQEDSDTGNDTSPEDIGAKDCPDHSQSPGQPSKDEDTLTEATEKTDSGPDDDTYRSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSAVQQVAQKLVQRGKKMKQPKRDAKESTEETAHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKEAPTSSSSNSTSTEASGGSSEKGRTKREFICSICGRTLPKLYSLRIHMLKHTGVKPHACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYFCSICGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTGERPYVCPVCSEAYIDARTLRKHMTKFHRDYVPCKIMLEKDTLQFHNQGTQVEHAVSILTADMQEQESSGPQELETVVVTGETMEVLEAVAATEECPSVSTLSDQSIMQVVNYVLAQQQGQKLSEVAEAIQTVEVEVAHMPEAE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 11.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EPOP_HUMAN
Sequence: METLCPAPRLAVPASPRGSPCSPTPRKPCRGTQEFSPLCLRALAFCALAKPRASSLGPGPGELAARSPVLRGPQAPLRPGGWAPDGLKHLWAPTGRPGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPRESTTSFASAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRSKLWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAPPPRTAQPRRPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHPLWRWQMGGPAVPEPPGLKFWGINMDES
What is the function of this protein?
Scaffold protein that serves as a bridging partner between the PRC2/EZH2 complex and the elongin BC complex: required to fine-tune the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells (ESCs).  Plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression at PcG target genes: acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EZH2 complex.  Interaction with USP7 promotes deubiquitination of H2B at promoter sites.  Acts as a regulator of neuronal differentiation.
What are the official names of this protein?
Elongin BC and Polycomb repressive complex 2-associated protein, Proline-rich protein 28.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes at both PRC2/EZH2 sites (H3K27me3) and broad H3K4me3 sites on chromatin of embryonic stem cells (ESCs).
Protein: YR857_MIMIV
Sequence: MLGEGSDFFDQGGYKFLRCYNNESIGFTVVMNLRANISAKPYYVGTETKYGELLPKNKFYATKAKVSRIKTIDEMDVPDKFFDEFQCYAYDGTKLKKFFPGQTIRNMNFYRDSEDIYEDIVDVRLENQSLEEQLEDFKECSRALKKYDNFWRSDRAKYLKLQEHCDNEYNRVLDKINNKK
What are the official names of this protein?
Uncharacterized protein R857.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L74/L77/R857 family.
Protein: SCPA_LACPL
Sequence: MTNNQQQPITIKISEFEGPLDLLLHLIRQNKMDIYDIPIAAITQQYLDYLHSMRALKLDIAGDYLVMAATLMTIKSRFLLPQPEPDEMDEDNEDDDPRDSLVAELLAYKVYQEAAGELREKEQARHQHFTREAMLVPADLSAPKLTAGITLDDLQAAFRQLVAKRRRVRPLTKTVVAETINIDERMTQITTQLQHQPQGLDFADLFTVSASDEMLVTTFMAVLELTKQDQVALQQAEPLSPIHLYLRQDEQHDEH
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: UBC_ASFP4
Sequence: MVSRFLMAEYRHLTENPSENFKVSVNENNMTEWDVILKGPADTLYEGGLFKAKIGFPPNYPYEPPRLTFTSEMWHPNIYSDGRVCISILHGDNAEEQGMTWSPVQKIDTILLSVISLLNEPNTDSPANVDAAKSYRRFVHKEDLESYPMEVKRTVKKSLDECSPEDIEYFKNAASNVPPIPSDAYEDESEEMEDDTYILTYDDEDEEEEEDEEMDDE
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (By similarity).  Performs the second step in the ubiquitination reaction that targets specifically a protein for degradation via the proteasome (By similarity).  By controlling the ubiquitination status of specific host proteins, the virus may target them to degradation and thereby optimize the viral replication (By similarity).  May be implicated in the shutoff of protein synthesis through its interactions with components of the host translation machinery (By similarity).  Blocks p65 nuclear translocation upon cytokine stimulation, thereby impairing NF-kappa-B signaling (By similarity).  Inhibits type I IFN production and 'Lys-63'-linked polyubiquitination of host TBK1 through binding to host RNF138.  This binding enhances the interaction between RNF138 and RNF128 and promotes RNF138-mediated degradation of RNF128.  Also inhibits the activation of AP-1 transcription factor (By similarity).  Monoubiquitinates the viral protein P15/PIG1 in vitro (By similarity).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2, E2 ubiquitin-conjugating enzyme, UBCv1, Ubiquitin carrier protein, Ubiquitin-protein ligase, pI215L.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion. Note=Accumulates in the perinuclear cytoplasmic viral factories. Faintly detected in the nucleus.
Protein: HUTI_CAUVC
Sequence: MRCDRVWINARLATLAPGRQGLGIVEDGVVACLGGRIAYAGPAAAAPTFEAAESIDVDGRWITPGLIDPHTHLVFAGDRAHEFELRLAGASYEEIARAGGGIVSTMRATRAASEAELIAAALPRLDALLAEGVTTVEIKSGYGLSLDDELKSLRAARALADIRRVGVTTTFLGAHALPPEYRDDEDGYVDLVCQTMIPAIAARGLADAVDGFCEGIGFSPAQIRRVFDAAKAHGLPVKLHAEQLSNLSGAALAAEYNALSADHLEHLDAAGIAAMAASGTVATLLPGAYYFTRETLVPPIAALRAAGVPMALATDCNPGTSPLTSPLLVMNMAATLFRMTVEECLAGVTREAARALGLLADRGTLEAGKACDLAIWDVERPAELVYRMGFNPLHARVWRGL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DARCY_CHRVO
Sequence: MKPIYARYPEVRMRWFDAEAFSARCSDVAMFETESVPAFYYLIDALRDSPLMTEPYFEFVDIIPAVEDGFRDYDAQLAQ
What are the official names of this protein?
Darcynin.
What is the protein family that this protein belongs to?
Belongs to the darcynin family.
Protein: PG095_FOWPN
Sequence: MGAAASIQTTVTTINKKISEKLEQTASASATANCDINIGNIIFKKNKGCNVLVKNMCSANASAQLDAIVSAVREVYDQLTEQQKAYAPSLLTAALNIQTNVSTITQDFETYIKQKCNSDAVINNIINVQSLEVDECSAPPGQIMTFEFINTGTATGNCAMKSVLDVLTKSSDRVSGNQSTGNDFSKYLYIIGGIICFLILLYYAKKLFFMSTNDKVKVLLAKKPDVHWTTYIDTYFRSSPVLV
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex associated protein OPG095, EFC-associated protein OPG095, Protein L1, Protein L1 homolog, Virion membrane protein M25.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG095 family.
Protein: 3NO25_WALAE
Sequence: MKTLLLTLVLVTIVCLDLGYTLTCLICPKKYCNQVHTCRNGENLCIKTFYEGNLLGKQFKRGCAATCPEARPREIVECCSRDKCNH
What is the function of this protein?
Three-finger toxin that binds and inhibits the muscular nicotinic acetylcholine receptor (nAChR).  The neuromuscular block is irreversible in chick biventer cervicis, but partially reversible in the rat diaphragm preparation.
What are the official names of this protein?
Three finger toxin W-V.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLV_ECODH
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTRC_SALTY
Sequence: MTHSLIIEEVLAHPQDISWLPWAVQYFFFIGIAACAALFACYLHWRKKDAATEENRALLIAITCAITAPLALTADLHQTARVWHFYAWPTPWSWMPWGALFLPLFTGFLALWFLAQQIKRLFNKSYNVTKWLALASALCAVGLLIYTGREVSVVLARPIWFSYAFPVAMFLSALQAFFALMIVAARRDSVRLPKILWGQIWTLAALGLVVAMWVSGDTLSGTAIRQWITVALSAKYYAVGWVALWVCTLLFCSLALRHPLSQLRRVLLVLSALALCWLMRWTLLIQVQTVPKFNAQFNPYSLPGGTDGWLAILGTFGLWIALLIIIRETLNGLTRRLQHG
What is the function of this protein?
Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate.  TtrC probably anchors TtrA and TtrB to the periplasmic face of the cytoplasmic membrane.  May transfer electrons from membrane quinol to TtrB.  During mice infection, the ability to use tetrathionate as an electron acceptor is a growth advantage for S. typhimurium over the competing microbiota in the lumen of the inflamed gut.
What are the official names of this protein?
Tetrathionate reductase subunit C.
What is the protein family that this protein belongs to?
Belongs to the NrfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_THEPX
Sequence: MRKAEVKRKTKETDIYAELNIDGKGNYDIATGIGFFDHMLSLFAKHGLFDLKVVAKGDLEVDTHHTVEDVGIVLGNAFLKAAGDKKSIKRFSTFYVPMDEALVRVSVDISGRSFLYCDLPLKAERVGNFETENVEEFLRAFAYNFGITLHVELLHGGNSHHIIEATFKALGRALDEALRIDERAEGIPSTKGIL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.