PharMolix/UniProtQA huggingface dataset:
Protein: DUT_PROA2
Sequence: MLKVNIVRVNKNAILPRYATQHAAGMDIAACLDVPLTIQPSETVLVPTGLAVELPEGYEAQLRPRSGLALKYAISLPNAPATIDADYRGEVKVILVNLGQEPFCVNHGDRIAQMVIARYEHAELQEVEELSRTPRGSGGFGHTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL14_MYCSS
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKEAIPGANVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIKNDNDPRGTRIFGPVGRELREKRFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CINAL_CYAP4
Sequence: MNQSAEIICVGTELLLGEILNSNAQFLAQQLAQLGIPHYYQTVVGDNPVRLKKAVAIACERSRLLIFTGGLGPTPDDLTTETLADFFDLPLVEHPEILADITRKYAHRGRTITANNRKQALLPLGAAILPNPTGTAPGMIWHPRPSLTVLTFPGVPSEMQCMWQETAIPYLRAQGWGQEMIYSQVLRFWGIAESALAERVAPFLELASPTVAPYASHGEARLRISVRAANETEALEQIQPIATQIHQLTGLDCYGSDEDSLASVLGKLLHSRQETLSVAESCTGGGLGQMLTAIPGSSAYFWGGVISYDNQVKISLLGVDPDTLTRVGAVSAAVAEQMALGVRSRLETTWGLSITGIAGPGGGTETKPVGLVYIGLAGPAGVEHYECRFSDFRGRDWIRHLSACTALDYLRRKLLTLG
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL333_BACLD
Sequence: MRVNITLACTECGERNYISTKNKRNNPDRVEFKKYCPRDKKSTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y258_MYCPN
Sequence: MSKIAFRMENICKSFDNGRVKANVDVNLTVYENTVHTLLGENGAGKSTLTSILFGLYQPDSGKIFIGEEEVHFKSSKDAVQHKIGMVHQHFKLVDNYTVLDNIILGNESSFSIPFTNGKLKLPLLHRKASEAKIQAMMERYDLHVNLHQKVSRLTVGQQQRVEILKVLFRDSDILIFDEPTAVLSDQEIKSFLNIIKNFKKMGKTIVLISHKLNEIKEVAETATILRQGHSVGTFQIKDTSIDEMARLMMGKELKETKNNTQFTAKGEPVLKVENLHLYLNQNWFYKLIARWNQKRINQLQKQGKPAKTLWLKSWLEGLAAIEKTPRFIRGIVNNLGFGSQQVFDKGISFEIHKGEIFAIAGVEGNGQNQLIDLICGLEKAAPKKVFFNGFDISRYSIRKRINAGIGFVLEDRHKYGLILDQTVRFNAVNNQIDRKQFSSWNFLNQMQIAVYTNQIVDKFDVRGAVQGTAIVRLLSGGNQQKLIIGRELTKQNELLVFAQVTRGLDVGAISFIHQKILDAKKQNNAILLVSYELDEILAIADTIGVINKGNLLEVNKRDVMTRERIGKLIMQ
What is the function of this protein?
Part of the ABC transporter complex involved in carbohydrates import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative carbohydrate transport ATP-binding protein MPN_258.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PURA_SODGM
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVVSIIANGVVLSPEALMKEMGELEARGIPVRERMLISEACPLILAYHVAMDVAREKARGAKAIGTTGRGIGPAYEDKVARRALRVGDLFNKDTFATKLKEVVDYYNFQLVHYYQADTVDYQMVLDDILAVAYVLTGMVVDVSELLDSARKRGDLMMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELFDDTGEFLCVKGNEFGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLQEVKICTAYRLPDGRVVESTPLAAENWEGIEPIYESMPGWSESTFGVKAFDKLPEAARRYIKRIEEVTGVPVDIVSTGPDRSETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_CORJK
Sequence: MTTNNQNAVTVTVTGAGGQIGYSLLFRIAKGEVFGDRVVNLRLLETEQGVQAARGVALELADCAFPLLGEVSITTELSEGFKDANAVFLVGAKPRQKGEERADLLAANGKIFGPQGKAIAEYAADDVRVIVVGNPANTNAAIVAAHAEGLDPRRVTALTRLDHNRGLAQVADKLGVAVRDLKNMTVWGNHSASQFPDVAELTLNGEKVADKLDAAWVNDEFIPRVAKRGAEIIEVRGRSSAASAASAALDHMRDWVNGTAEGDWVSVALPSDGSYGIPEGLVFSFPCRSVDGEWEIVQGLEISPAQQERIDANIKELQEEKAAVEEAGLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: PYRR_STAA9
Sequence: MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: SYDP_CROS8
Sequence: MQNEVQQALAAFSARYCEAWRQQRGSLPVSEEYIGISSPCIVSTHPDAVEWEPQPFTPEDSLGAVEKALDIVIQPDVHAFYASQYAGDMAARYDDVALTLLQAWSQDDFRRVQENLIGHLVTQKRLKLSPTIFIATLDSELDVISLCNLTGEVVQETLGTRKRRVLAPSLSTFLSQLTPLV
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: ECHP_DANRE
Sequence: MARYELVKRSVALITLTNPPVNALSSAVRHAISKTMERALSDPKVTAVVICGENGRFCGGADIREFAGPLRGPPLVPLLDAIEAGEKPVVAAIEGVALGGGFELALVCHYRIAHYKARLGLPEVTLGILPAAGGTQRLPRLIGIPAALELITTGRHVSAQEALKLGMVDQVTEQNTCEVALEFALKAVGKPLSSRRLSMLTTPCPPGLDGIFEAATMQVQKKARGVMAPLACVQAVRAATLPYSEGIKREGELMATLFSSGQAQALQYSFFAQRTAEKWTLPSGAQWNNSKPREIQSAAVIGLGTMGRGIVVSLARVGISVIAVESEKKLLETGRQMVIGMLERDAKRRGVSASLNLLKFSLSLQDLKDVDLVIEAVFEDMALKKQIFRELSRVCRPATLLCSNTSGLDVDALADVTDRPQLVAGMHFFSPAHVMKLLEVVCGPRSSKEAIATAMSLGKRMGKVSVAVGNCPGFVGNRMLMPYLEQATFLLEEGATPQQIDKALEDFGFAMGVFRMSDLAGLDVGWRVRKESGLTGPDVDPKDPPRRRQGRKYCPIPDMVCQQGRFGQKTGRGWYMYDKPGDTNAKPDPLIQNLLETYRSRYGIQPRKITDQEIIERCLFALANEGFRILKDKIAGQPEDIDVIYLFGYGFPRHRGGPMFYASMVGLERVLERLEYYHHALPDVPHLEPSPLLKKLVARGSPPIQKWREHIKSMHSHL
What is the function of this protein?
Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.  Catalyzes two of the four reactions of the long straight chain fatty acids peroxisomal beta-oxidation pathway (By similarity).  Can also use branched-chain fatty acids such as 2-methyl-2E-butenoyl-CoA as a substrate, which is hydrated into (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA (By similarity).  Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species.  Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity).  Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity).  Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (By similarity).
What are the official names of this protein?
Peroxisomal bifunctional enzyme, PBE, PBFE, Multifunctional enzyme 1, MFE1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PSAI_TUPAK
Sequence: MAASFLPSILVPLVGLIFPAIAMTSLFIYIEKQEVN
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y646_METJA
Sequence: MKARELFEKLKKELNNFSIYDIMMIRSFIEKDAKYLPPQYKNHYVEAMMKYLIETFNEIRKKSVDEIQDEEIDEEKLNEMLNRIERFRKYYTPDEERFINLSKILCPYLAFIAKKPLHPEYLTFPGNVKIIKKGNNYYCPVKNKQLNEYSLCEFCVCKSIDELK
What are the official names of this protein?
UPF0305 protein MJ0646.
What is the protein family that this protein belongs to?
Belongs to the UPF0305 family.
Protein: CHADL_HUMAN
Sequence: MEGPRSSTHVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEELEERAVAGPRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAARKAKRTPASRPSARRTPIKGRQCGADKVGKEKGRL
What is the function of this protein?
Potential negative modulator of chondrocyte differentiation.  Inhibits collagen fibrillogenesis in vitro.  May influence chondrocyte's differentiation by acting on its cellular collagenous microenvironment.
What are the official names of this protein?
Chondroadherin-like protein.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: FIBC_BPT5
Sequence: MISNNAPAKMVLNSVLTGYTLAYIQHSIYSDYDVIGRSFWLKEGSNVTRRDFTGIDTFSVTINNLKPTTTYEVQGAFYDSIIDSELLNAQIGINLSDKQTFKMKSAPRITGARCESEPVDVGVGAPIVYIDTTGEADYCTIELKDNSNANNPWVKYYVGALMPTIMFGGVPIGSYKVRISGQISLPDGVTIDSSGYYEYPNVFEVRYNFVPPAAPINIVFKAARIADGKERYDLRVQWDWNRGAGANVREFVLSYIDSAEFVRTGWTKAQKINVGAAQSATIISFPWKVEHKFKVSSIAWGPDAQDVTDSAVQTFILNESTPLDNSFVNETGIEVNYAYIKGKIKDGSTWKQTFLIDAATGAINIGLLDAEGKAPISFDPVKKIVNVDGSVITKTINAANFVMTNLTGQDNPAIYTQGKTWGDTKSGIWMGMDNVTAKPKLDIGNATQYIRYDGNILRISSEVVIGTPNGDIDIQTGIQGKQTVFIYIIGTSLPAKPTSPAYPPSGWSKTPPNRTSNTQNIYCSTGTLDPVTNQLVSGTSWSDVVQWSGTEGVDGRPGATGQRGPGMYSLAIANLTAWNDSQANSFFTSNFGSGPVKYDVLTEYKSGAPGTAFTRQWNGSAWTSPAMVLHGDMIVNGTVTASKIVANNAFLSQIGVNIIYDRAAALSSNPEGSYKMKIDLQNGYIHIR
What is the function of this protein?
Probable central straight fiber at the tail tip.
What are the official names of this protein?
Straight fiber protein pb4, pb4, Tail protein pb4.
What are the subcellular locations of this protein?
Virion. Note=Component of the tail.
Protein: RL18_BURMA
Sequence: MDKTQSRLRRARQTRIKIAELQVARLAVHRTNTHIYAQVFSPCGTKVLASASTLEAEVRAQLADKSGKGGNVAAATLIGKRIAEKAKAAGIESVAFDRSGFRYHGRVKALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: KPYA_TOBAC
Sequence: MSQALNFFVSSSSRSPATFTISRPSVFPSTGSLRLLVKKSLRTLVVEASSAAASDLDEPQSSPVLVSENGSGGVLSSATQEYGRNAAPGTDSSSIEVDTVTEAELKENGFRSTRRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEEKGFAVAIMMDTEGSEIHMGDLGGASSAKAEDGEIWNFTVRSFDPPLPERTVTVNYDGFAEDVKVGDELLVDGGMVRFEVIEKIGPDVKCLCTDPGLLLPRANLTFWRDGKLVRERNAMLPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIESIDSLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLESMIEYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLRIERMWREQKRHEVIELPSIASSFSDSISEEICNSAAKMANNLEVDALFVYTKNGHMASLLSRCRPDCPIFAFTTTTSVRRRLNLQWGLMPFRLSFSDDMESNLNKTFSLLKARGMIKSGDLIIAVSDMLQSIQVMNVP
What are the official names of this protein?
Pyruvate kinase isozyme A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECA_SALPA
Sequence: MAIDENKQKALAAAMGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNATPDFAVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_VIBVU
Sequence: MKKIEFELHYQAQKALHACIDKANRYFQRQFPMPLLSYQLRGKAAGKAYLQLNQIRLNPILFKENKTAFLEEVIPHEVAHLLTYQLYGRVKPHGAEWQSIMQGVFLLPANTTHQFAVASVQGKTFQYRCQCREFPLTIRRHNKVLRNEASYTCQKCRQTLIFTGIQLS
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_XANOR
Sequence: MSEKATEIANLLSPTVDSLGVELLGVEYLPAPGGATLRLYIDVPLAEQPERVINVDDCERVSREVSAQLDVEDPISGHYTLEVSSPGVDRPLFTLEQFARHAGESTKIVLKLAQDGRRRFQGEILRIDAEAGAVVFAIDGKDVQIGFDNIDKARILPDWVALGLAPQKPNKPGPKKTGHEKKKPSNESAAGKPRAE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHB_RAT
Sequence: MAAVVGVSLKRGFSATALGRVGLQFQACREAQTAAAAAPRIKTFAIYRWDPDKAGDKPRMQTYKVDLNKCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTDLGKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEDREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDEFTEERLAKLQDPFSLYRCHTIMNCTQTCPKGLNPGKAIAEIKKMMATYKEKRALA
What is the function of this protein?
Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LICH_CROAD
Sequence: MWRLIIIAILFQGLVNSAMLERRKRGVDPETAMNISEIILFRGYPSEEYEVVTGDGYILCLNRIPYGKISQKTKEPKPAVFLQHGLLADGSNWVTNLDYNSLGFALADAGFDVWLGNSRGNTWSQKHINYTIKQKEFWMFSFNEMAMYDIPASVNFVLNKTGQEQLFYVGHSQGTTIGFIAFSVLPELAKKIKMFFGLAPVMTVKFSSGGLVKLGELPEFLLKEIFGTKQIFPQNAVIKWLATHVCGQVLIDELCGNFFFLLCGFNEKNLNMSRVEIYSTHCPAGTSVQNMLHWSQAVKSGEVRAFDWGSRKENMAHYKQPTPPPYKMERMLVPTALWTGGHDWLSDRKDIAILLTLIPNLIYHKEIPEWEHLDFIWGLDAPQRMFRDMIQMMHKVQYAH
What is the function of this protein?
In physiological conditions, is crucial for intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles.  In venom, the biological contribution is unknown.
What are the official names of this protein?
Putative lysosomal acid lipase/cholesteryl ester hydrolase, Acid cholesteryl ester hydrolase, LAL, Cholesteryl esterase, Lipase A, Sterol esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y117_ABVP
Sequence: MSESKRKYYLPYEVRQXFDAVAGRIKYMICQFEHEHVTGPYDAVILFDGLLLRLKDLAENDFIDERIEQVKNVYYQVGKFSDNIVWNYEVHRYYHPDEIVDFIEVIYDSLKKIYEIE
What are the official names of this protein?
Uncharacterized protein OR117.
Protein: XNI_ECO57
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: RUVB_CAMC5
Sequence: MDRIVEIEKVSFESEFEVSLRPSSFDDYIGQEKIKQNLDVFIKAAKKRGECLDHVLFYGPPGLGKTTLAHIIANEMAVSIKMTAAPMIEKSGDLAAILTNLQEGDVLFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPKFTLIGATTRAGMISAPLRDRFGMDFRLQFYSTAELSRIIQIASVKLGKECDKAAALEIAKRARATPRIALRLLKRIRDFAEVNDEAMISHERAKEGLNALGVNSLGFDEMDIKYLEILLDAKRRPLGLSTIAAALSEDEGTVEDVIEPYLLANGFIERTAKGRIASEKCFETFKIKLNRTKGLFDGE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TBCA_DICDI
Sequence: MVLDTKRSLKIKIDALKRLEKDYMLYKKEEQLQIENVERFKADETKDIYDVKKQIEILDENKTMIIDSVSRVTAFLVQFSEFLEEHKNEDDGSEIWKDSYDIIDQISTKFLGE
What is the function of this protein?
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone A, Tubulin-folding cofactor A, CFA.
What is the protein family that this protein belongs to?
Belongs to the TBCA family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: OCA5_YEAST
Sequence: MHDKKSPMANSHYLKNLKQQFRNKNLIETTIHLVKCNDHDSLAFLARTYGVPPQLRHVVWPILLKYHPMCISPNITSNTISWDPITNDFILNDPFLKSKAPTDKQDKSDDENILPYDIESIILHDLKKYFHSRSNPAGSSSNANTTNIATPTPVSSSDASTISSMEVLSPSLDYEFQIIETLKNAIVKFLLKWSKIFKYESGLAWIALGLAEWYPIYPYETMSPFNETHSFYEVEDYVVLSGRKHALLSTNNGNNGNSNSSSNNTNNNNTNITSGMHNLSINTNTSLHNSPYISHTLSYLYKEYPLPFELRSKLPTKPIFSFSALFERLALVILHCPDTILAHKQLKNDSNASSSSKANSNFNTNYFPIISGGDLSFQTQVFFKVFSSILPELYQPLTEESSLQPSSSRNSWIYWWLKCSGAKALQRQDRGRVWDLLLGWRPKPNMDTINFFLNYNDKKMDHLYHDTPQCDNEQYWMKDWIALYNNDPFWFPDLDSMALGSKKFPYDYSVFKELILRNRYGGTQSKAQKDNTVPSPGSDSNDKSELKLPFSSIDPHMQLIFIFIAILQFNEFKLLEFEEAEISEFLNNVPLLTKFDDSSYRKLYENTESSITSLPSSPTTSTMASLQSSSNSSAHISNYHMLIEVGNDAKASHCFDDLLNMAGDIWRKWLWRELEESSL
What is the function of this protein?
Required for replication of brome mosaic virus (BMV), a positive-strand RNA virus.
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_DESDA
Sequence: MAEIKVKLVRSRIGASPAQRKLLDSLGLKRREMVKTFKDTPAIRGIIAKVPHMVAVVE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TVP18_AJECN
Sequence: MTIAEEFKSRNFSIYGQWTGVLCILLCFALGIANIFSKVIAFSIVCLASSFVIIFVEVPLLLRICPTSSTFDSFIRRFTTNYMRALMYVILSVVQWLSLIVGPSSLLAAAVVLSVSAIFYALAGITKQEFMGSKTLGGQGVAQMIV
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: MIRO2_RAT
Sequence: MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTEEELQEEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTIEAVLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRLSDQDLDHALSDKELNAFQKSCFGHPLAPQALEDVKRVVCKNVAGGVQDDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSLELTPDYLCPPLYVPPGCSTELNHRGYQFVQRVFEKHDQDHDGVLSPTELESLFSVFSVAPWGPELLHTVPTEAGCLSLRGYLCQWTLVTYLDVQHCLAHLGYLGYPTLCEQDSQAQAITVTREKRLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGHSLGEARDRDAPEKLPTHTINTVRVSGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPETFVQCATIYKRYYMDGQTPCLFISSKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAQSSIDVFTQLATMATFPHLAHTELHPTPFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
What are the official names of this protein?
Mitochondrial Rho GTPase 2, MIRO-2, Ras homolog gene family member T2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Colocalizes with MGARP and RHOT2 at the mitochondria.
Protein: RIBD_HAEIN
Sequence: MLEFSSQDCVFMQRALDLAAKGQYTTTPNPSVGCVLVKNGEIVGEGFHFKAGQPHAERVALAQAGENAKGATAYVTLEPCAHYGRTPPCALGLIEAGVVKVIAAMQDPNPQVAGKGLKMLSDAGIESTVNLLNDQAEKINKGFLKRMRQGMPFVQLKLAMSLDGRTAMASGESKWITGPDARSDVQKMRAKSSALLSTSTTVIADDPSLNVRWDEFPENLKTEYKKEWLRQPVRVILDSQHRIQPTHKLFLTHSPVWLVSSEPRDLTGFPDFCEQIIFPKENLLKELMRELGKRQINTLWVEAGANLSGSLIDAKLVDELIIYIAPKLLGDNARGLCQLPNLTKLADAPLWQLNELEQIGDDIKLTYTPKGV
What is the function of this protein?
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HTP reductase family.