PharMolix/UniProtQA huggingface dataset:
Protein: ZRAN1_HUMAN
Sequence: MSERGIKWACEYCTYENWPSAIKCTMCRAQRPSGTIITEDPFKSGSSDVGRDWDPSSTEGGSSPLICPDSSARPRVKSSYSMENANKWSCHMCTYLNWPRAIRCTQCLSQRRTRSPTESPQSSGSGSRPVAFSVDPCEEYNDRNKLNTRTQHWTCSVCTYENWAKAKRCVVCDHPRPNNIEAIELAETEEASSIINEQDRARWRGSCSSGNSQRRSPPATKRDSEVKMDFQRIELAGAVGSKEELEVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQDMLAILLTEVSQQAAKCIPAMVCPELTEQIRREIAASLHQRKGDFACYFLTDLVTFTLPADIEDLPPTVQEKLFDEVLDRDVQKELEEESPIINWSLELATRLDSRLYALWNRTAGDCLLDSVLQATWGIYDKDSVLRKALHDSLHDCSHWFYTRWKDWESWYSQSFGLHFSLREEQWQEDWAFILSLASQPGASLEQTHIFVLAHILRRPIIVYGVKYYKSFRGETLGYTRFQGVYLPLLWEQSFCWKSPIALGYTRGHFSALVAMENDGYGNRGAGANLNTDDDVTITFLPLVDSERKLLHVHFLSAQELGNEEQQEKLLREWLDCCVTEGGVLVAMQKSSRRRNHPLVTQMVEKWLDRYRQIRPCTSLSDGEEDEDDEDE
What is the function of this protein?
Ubiquitin thioesterase, which specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin (PubMed:22157957, PubMed:23827681, PubMed:25752573, PubMed:25752577).  Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones (PubMed:18281465).  Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription (PubMed:18281465).  Acts as a regulator of autophagy by mediating deubiquitination of PIK3C3/VPS34, thereby promoting autophagosome maturation (PubMed:33637724).  Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987).  Required in the stress fiber dynamics and cell migration (PubMed:21834987).
What are the official names of this protein?
Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C64 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Protein: EF2_BOVIN
Sequence: MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPATGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEETQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNTSRPSQVVAETRKRKGLKEGIPALDNFLDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C- terminal cleavage product.
Protein: SWI6_MAGO7
Sequence: MASTVAGNSFVSQQHPGNLHSANLQSQSQGFRRQNSTSSVPSTASFDPPNGSIANTGSQKHHPMSSQQSQPPASQQSFSMSQTGSQPQPSQSSFRSYSDQNVPQQPQEASPIYTAVYSNVEVYEFEVNGVAVMKRIGDSKLNATQILKVAGVEKGKRTKILEKEIQTGEHEKVQGGYGKYQGTWIKYERALEVCRQYGVEELLRPLLEYNRNPDGSVSQANLNTPTKEQAMAAQRKKMYNSGADSRNNNGGGTFFKNISQTAHSAMTAISKARFDSPGPRGRNGPTRAPSFQRQLSTQSIDDFHGGNSQASNFAENFPPQDVNMAFSAGSEPQPGGLNGTEPPRKRQRMDMTPANSFGAYANNSQMQAYADAFPGSPTEPNDSFIYTQHAAANDTLLQQQHDQQTPLQPLPYEQSVEAENKRSMLMSIFMNDGMSEQARVDTLRQIHPRDLDMPIDSQCHTALHWAATLSRMTILRRLIEAGASPFRVNTSGETPLMRACIVTNSHDNDSMPAILDILGNTMEVRDSKERTVLHHIALTSAVSGRSAASRYYLQCLLGWVVRQGAANGGQLNSQTFNGGATVSQSQNATRLDLGRFMSEMLNAQDSAGDTALNIAARIGNRSIISQLLEVCASPHIANRSGLRPTDFGIGVDSDGAMKTKGDSGGDVENGDVGGSSQKSNESSNEIVTSITHLLTETSANFQEEIKNKQKNIDSLHATLRLTTTDVNDLRRKLDEAQARVKAQQLARQKVTNLQRAEERERYRLTQLEQTTGRRDIASANGWEAESNTLLATINATTNGEPDADAKLPSSALLRARIEAVKKQTESTRQSVVALKGRSREVEGRYRHLVALATKCRDEDVDSTMEGLLKAVESEKGELEIGRVRRFLGGVEGVIG
What is the function of this protein?
Transcription factor that plays a role downstream of the MCK1-MKK2-MPS1 cascade (PubMed:22321443).  Required for hyphal morphogenesis and pathogenicity (PubMed:22321443).  Is an important oxidative stress response regulator and plays a positive role in the regulation of extracellular peroxidases (PubMed:22321443).
What are the official names of this protein?
Transcription factor SWI6.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSP2_PSEAE
Sequence: MSQTPSLAQLQPADAFLRRHLGPDPAEQQAMLAFLGVSTRAELIVQTVPPAIRLNRPLELPAALDEQAALARLRGYAGLNQRWTSLIGMGYYGTVTPSVILRNVLENPGWYTAYTPYQPEIAQGRLEALLNFQQLTIDLTGLDLASASLLDEATAAAEAMALARRVAKARSNRFFVDAHCHPQTVSVLRTRAEAFGFELVVDEPDNLAAHAVFGALLQYPDSRGEIRDLRPLIEALHGQQALACVASDLLALLLLTPPGELGADVVLGSAQRFGVPMGYGGPHAAFFATREGYKRAMPGRIIGVSRDARGNPALRMALQTREQHIRREKANSNICTAQVLLANIASLYAVYHGPQELKRIAQRVQRLTALLAAGLKSKGLRRLNRHFFDTLTYEVGERQAAILERARAARVNLRVVDDRRLALSLDETCDAATLATLFEIFLGAGHGLDVAHLDGGAVADGIPAVLQRTSAYLQHPVFNAHHSETEMLRYLRQLEGKDLALNQAMIPLGSCTMKLNASSEMIPITWPEFAELHPFVPREQAEGYRRMIDELEAWLRAITGFDAICMQPNSGAQGEYAGLLAIRRYHQSRGDSQRDICLIPASAHGTNPASAIMASMRVVIVECDPRGNVDLDDLRLKAAEAGDRLSCLMITYPSTHGVYEEGIGEICEVVHRHGGQVYMDGANLNAQVGLARPADIGADVSHMNLHKTFCIPHGGGGPGMGPIGVKRHLAPFVANHPVIRVEGPNPLNDAVSATPWGSASILPISWMYIAMMGPQLADASEVAILSANYLANRLDGAFPVLYRGRNERVAHECILDLRPLKAQTGITEEDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESKAELDRFVEAMLSIRAEIGKVESGAWPAEDNPLKRAPHTLADVTGIWQRPYEIAEAVTPSEHARAFKYWPAVNRVDNVYGDRNLFCACVPLDDYRE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating) 2, Glycine cleavage system P-protein 2, Glycine decarboxylase 2, Glycine dehydrogenase (aminomethyl-transferring) 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: TOLB_LEGPC
Sequence: MFNRIISLFLLLFTGQVIALDLELTQGINSALPIAINSFGSDAAAQEIGNVIENDLTISGQFKIISGPQGANSQSSVSTLRQLGADSVVTGRVNQVGNRIEVSFTLADAVANGNILLTKTFQINANQVRALAHHISDEVYQKLTGERGIFSTRIAYISVQRNGGRSRYSLEVADADGHNPQSLLVSSEPIMSPSWSPNGKSISYVSFEKKKAEIFTVSVETGQRRLITSFPGINGAPAWSPDGQHLAVVLSKSGTPKIYDVDLSSGSMKQLTFGNSIDTEPRYSPDGRSLLFTSGRGGSPQVYRLSLADGQISRVTFEGNYNARASYTPDMKHIVMLHREDRQFNIGVQNTGGGPISNLTFSGLDESPSVSPNSRLVLYATRYQNRGVLGIVSIDGRIRMRLPAREGDVQEPAWSPYLS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLMS_AGRFC
Sequence: MCGIVGIVGTQPVAERLVDALKRLEYRGYDSAGVATIDNGAMDRRRAEGKLFNLEKLVSEKPLPGVVGIAHTRWATHGVPNEINAHPHFVDGVAVVHNGIIENFSELREELSAEGATFTTQTDTEVVAQLLAKYTREGLGHREAMLKMLNHVTGAYALVVMFQDDPGTLLSARSGPPLAVGYGRGEMFLGSDAIALSPFTNEITYLVDGDCAIVTRDGAEIIDFSGKPVKRERQISQATAFVVDKGNHRHFMEKEIYEQPEVISHALSHYVDFATRTVKDADKAIDFASLSGLAISACGTAYLSGLIGKYWFERYARLPVEIDVASEFRYREIPLVPTQAALFISQSGETADTLAALRYCQQEGLKIGAVVNTRESTMARESDAIFPILAGPEIGVASTKAFTCQLAVLASLAVAAGKARGTLKPGEEKQLVQQLIEMPRIMSKVLNVIQPQIEALSRDLSRFKDVLYLGRGTSFPLALEGALKLKEISYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRFFEKTVSNMQEVAARGGRIIFITDEKGAAASKLETMATITLPNVDELIAPMVFSLPIQLLAYHTAVFMGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBBO_ECOLI
Sequence: MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG
What are the official names of this protein?
Uncharacterized oxidoreductase YbbO.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PLP1_CAEEL
Sequence: MSDGSVERGTKRAEDSLATHQLTVQYKRYYIDVNENTRGRYIKIAELGTNYKSRIILSIVAAKAIVSEISKMLALIDEPSTGEHAPKESSLIKSETLNVDGRKFYVDLKENVRGRFLRIAQMPMNPRQTRQQIAIPSDGIAEIHKVLTEYLAKFGEGHEQENTNTPKITAENKSFLFHSGKNDRGEFVRISEIKLNSGYRNAITVPMSALVDFRKELDNIIANQGK
What is the function of this protein?
Probable transcription activator (PubMed:19084000).  Binds telomeric DNA containing repeats of the sequence, 5'-TTAGGC-3' (PubMed:16267406).  Binds to end-1 promoter, activating end-1 expression, which is required for endoderm specification during embryonic development (PubMed:19084000).
What are the official names of this protein?
Transcriptional activator plp-1, Pur-alpha-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the PUR DNA-binding protein family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=localizes to nuclei of interphase cells throughout early embryogenesis. Localizes to the nucleus in a lit-1 dependent manner. Transiently asymmetrically localizes during telophase of the dividing EMS cell with higher levels in the future E cell nucleus and low or undetectable levels in that of the MS cell.
Protein: LIPB_DESVH
Sequence: MLTIDLGSLSYAEAEAVQTARLGEVSTGGEDTLYLVEHPPVITLGRNGGIENLHAGRGFLAERGIELAQSSRGGNITCHFPGQLVAYPVFRIERRPGGLRSFFHDLEEVVLRTLHTFGLEASRHEGRPGVWIDNRKICSIGVAVRRWTTYHGLALNVGRDLSLFNLITLCGLPDAEATSLHRELDDDSVTMQEVKDVLTRQFLAIFTHPAVAAGEAAL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLDP_ECO57
Sequence: MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWRGIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFRFGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEWVINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPSDAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP
What is the function of this protein?
Uptake of L-lactate across the membrane (By similarity).  Can also transport D-lactate and glycolate (By similarity).  Seems to be driven by a proton motive force (By similarity).
What are the official names of this protein?
L-lactate permease.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOH_COXBN
Sequence: MTDQLITLIWIIIKIVLILVPLLVAVAFITLAERKVIGYMQSRVGPNRVGFRGLAQPIADIFKLLLKEVIIPTASSRYLYLIAPILSLVPALAAWAVIPFAQGWVLANVNAGLLFLFAMTSLGVYGILVAGWASNSKYAFFGALRSAAQVVSYEIPMGFALVGVLLAAGTMNLQGIVLRQSGGLWHWFWLPLLPLFVTYWITAVAETNRAPFDVAEGESEIVAGFHVEYAGVTFALFFLAEYANMVLVSAIATVIFLGGWLSPFQGIPGLESLFAWVPGIVWFVLKLSLFIFTYFWMRATFPRYRYDQIMRLCWKVLIPVTLVWIIILALAIEFHWTHWL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RODZ_YERPY
Sequence: MNTEASQDQTVTETPGVRLRQARESLGLTQQTVAERLCLKVSTIRDIEEDNAQANLASTFHRGYIRSYAKLVHLPEDELLPILEKQAPVRAAKVAPMQSFSLGKKHKKRDGWLMSFTWLIVLVVLGLTGAWWWQNHQAQQAEIANMVDQSSAQLSQNGGQPVPLTDDNSDAIAPTDAPAPVANGQPVPLTNHSTSAVTNSATTSSATTSSVPTTSSVPKTTLVPKTTLVPKTNSTEPVDTANTNTTMHQEGAASAAVSPSQVPQLGMPTDQPPLPTADAGVSGSASSVGALVMNFTADCWLQVVDATGKTLFSGIQKGGAVLNLAGKAPYKLTIGAPGALTISYQGNPVDLSKFIKANRVARLTVGVE
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: PGK_STRU0
Sequence: MAKMTVKDLDLKGKKVLVRVDFNVPLKDGVITNDNRISAALPTIKYIIENGGRAILFSHLGRVKEEADKEGKSLAPVAKDLSAKLGTEVVFPGVTRGAELEEAINALEDGQVLLVENTRFEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVDKAVAGFLLENEIAYIKEAVEKPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDIAKELLEKSNGKLILPVDSKEANAFADYTEVRDTEGEAVSEGFLGLDIGPKSIAKFEEALEGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGLSALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URAD_MOUSE
Sequence: MDMVKVNSMDFGEFVDVFGNIVEKCPLIAAAVWSQRPFSGLEDLENHFFAFIDALPRSGQEGILRCHPDLAGRDLQQGTLTAESQREQSQAGLTSLDTDDRLRLQQLNAQYRERFGFPFVLAARLSDRATVPRELARRLQCQPESELRTALGEVKKISHLRLTDLLGAHSHSARVELP
What is the function of this protein?
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
What are the official names of this protein?
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, OHCU decarboxylase, Parahox neighbor, Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the OHCU decarboxylase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: COAD_STRMU
Sequence: MSDRIGLFAGSFDPVTNGHVDIIRRASGLFDKLYVGLFYNKDKTGLFEPARRQIMLKEALGDLKNVEVVAARDSLAVDIARQHQVTHLVRGLRNAQDLEYEANLAFFNSQLAKEIETVFLLTALDYRYFSSSRIRELIHFGADISPYVPQGVVKEVGKKCENKQKI
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMYD_CAEEL
Sequence: MSSYALYRGTTLGQALDKTLEDMESEGLLTKSLASKVLQQFDKSMNKQISRLPKEKMNFCATQLLTYRYCDNVWTFILNNVTLKDPQRSFDEPIDKLKVVACDGRQTSLLQTLSAQGPSKRVNRAHAAAAGDDEDDDSD
What are the official names of this protein?
Transcription initiation factor IIA small chain homolog.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 3S32_PSETE
Sequence: MKTLLLTLVMVTIMCLDLGYTLTCYKGYHDTVVCKPHETICYRYLIPATHGNAIPARGCGTSCPGGNHPVCCSTDLCNK
What is the function of this protein?
Binds with high affinity to muscle nicotinic acetylcholine receptor (nAChR) and hinders acetylcholine binding to the receptor, thereby impairing neuromuscular transmission.  Competes with the binding of alpha-bungarotoxin on muscle AChR (from Torpedo) with an IC(50) of 0. 30 uM.  Causes muscle paralysis, spasms and increased respiration.
What are the official names of this protein?
Short neurotoxin 2, SNTX2, Alpha-neurotoxin 2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type III alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL22_FRACC
Sequence: MADDLVDGLTRAGLPGAKASARYVRVSPTKARRVVDLVRGRSVGEALDILRFAPQAASEDVYKVVASAAANAENNHSLDPATLWVGEVYVDEGPTLKRIRPRAQGRAYRIRKRTSHITVVVESREPVSAAGRGAKTTRRAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: VP38_GAHVG
Sequence: MEFEAEHEGLTASWVAPAPQGGKGAEGRAGVADEAGHGKTEAECAEDGEKCGDAEMSALDRVQRDRWRFSSPPPHSGVTGKGAIPIKGDGKAIECQELTGEGEWLSQWEELPPEPRRSGNEHLDESRYAKQTERGSSTGKEEGDGMKQMGELAQQCEGGTYADLLVEAEQAVVHSVRALMLAERQNPNILGEHLNKKRVLVQRPRTILSVESENATMRSYMLVTLICSAKSLLLGSCMSFFAGMLVGRTADVKTPLWDTVCLLMAFCAGIVVGGVDSGEVESGETKSESN
What are the official names of this protein?
38 kDa phosphoprotein, Phosphoprotein pp38.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSG10_RAT
Sequence: MMRNRSKSPRRPSPTSRAANCDVDLLKSTARDREELKCMLEKYERHLAEIQGNVKVLTSVRDKTFLLYEQAQEEIARLRREMMKSCQSPKSTTAHAILRRVETERDVAFTDLRRMTTARDSLRERLKIAQAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETITIVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGATLNDLAKEKECLQTCLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQSTEALIMCEQDISRMRRQLDETNDELGQIARERDILAHENDNLQEQFAKVKQENQALSKKLNDTHNELSDIKQKVQDTNLEVNKLKNILKSEESTNLEVNKLKNILKSEESENRQIMEQLRKANEDAENWENKARQLEAENNTLKLELITAEAEGNRLKEKVDALNREVEQHLNAERSYKSQIATLHKSLVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMMENELDSARSEIELLRSQMTNERISMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHLGSMKPNTKCHSPERAHHRSPDRDLDRSLEENLCYRDF
What is the function of this protein?
Plays a role in spermatogenesis (By similarity).  When overexpressed, prevents nuclear localization of HIF1A (By similarity).
What are the official names of this protein?
Testis-specific gene 10 protein, Cp431.
What is the protein family that this protein belongs to?
Belongs to the CEP135/TSGA10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In mature spermatozoa, localizes to the centriole and midpiece (By similarity). The 27-kDa N-terminal fragment associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa fragment localizes to the midpiece (PubMed:14585816). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (PubMed:16643851).
Protein: CBIA_SULAC
Sequence: MRFPRIIISSDRSNSGKTLVTAGLIKVLSKRYKVRGYKVGPDFIDPMYHKIASGHPVINLDLWLMGESGVYSSLAKYGKHFDLGIIEGVMGLYDGLYEDYSTYKLSELTHTPLILVINCSNLSSTVGAIVKGLREYRNANVRGVIFNYIASEKHLDYCKKSIPENVEVLGYLPIDKSLSVPSRHLGLYTTEDFKNAKDVINATANLIEMNVDVDKIVEIAEEANELQESNEIEERNVVGKAYVAYDSAFSFYYDENIDILKKRYDVEFFSPLNNDAPADQPSFIYIGGGYPELHLEELENSTKTKDWIKRNVEKGVKLLAECGGFMFLSNEIINEKSYRMIGLYDIQIKAKDKLTIGYTELETEKDNLLSSKGESIRGHEFHVSKAVSVGDVNFAFKNKHGKGIWNGKDGVYVENSLGSYSHFHFSRTRRLLSF
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: MALA_STRPN
Sequence: MLPYPFSYFSSIWGVRKPLSKRFELNWFQLLFTSIFLISLSMVPIAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIGPSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQQNRVYISLFLVLGASFLFGLNFFIVSLGASFLLYITKRSRLFSFNTFKECYHFILNCLGLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK
What is the function of this protein?
Has a role in maltotetraose utilization.
What are the official names of this protein?
Maltodextrose utilization protein MalA.
Protein: RSMJ_VIBCM
Sequence: MLIQLICQAPQRAQELEQIAARWQLQASDDSPFALVLSEERLELRKLDEPKLGAIYVDWVEGAVAHRRKFGGGKGQSIAKAAGLNKGVTPVVLDATAGLGRDAFVLASLGCRVQMVERHPVVAALLEDGLQRAKQDDEIGAWVSERISLLHASSHDALQQLASDPNFTSPDVVYLDPMYPHPENKKKTALVKKEMRVFQSLVGADNDADALLEPALQLAQKRVVVKRPDYAPWLGNRKPSMAMETKKNRFDVYVIAAMSGE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_CLOD6
Sequence: MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGVPIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLVDDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEIISVSLLEIDGEDSVTIKE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: NU4LM_HERJA
Sequence: MSIVYINIFLAFIMSLLGMLIYRSHLMSSLLCLEGMMLSLFVMITLIILNNHFTLASMTPIILLVFAACEAALGLSLLVMVSNTYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.