PharMolix/UniProtQA huggingface dataset:
Protein: RS27A_METM5
Sequence: MAAKKGVKTSTKKSDYYKVEGNTVERLKKACPKCGAGVFMAEHLNRFACGKCGYLEYKKNEKTETEE
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: FRDC_ECO57
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIDC_ECO5E
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIBBA_CYTH3
Sequence: MEQIKLDSIADAIEAIRKGEVIIVVDDEDRENEGDFICAAECVTPEIINFMSKEGRGLICAPISEARCTELKLDLMVGSNTATHETPFTVSVDLLGNGCTTGISASDRSKTIRALVDPDTKPEDLGRPGHIFPLKAKDEGVLRRVGHTEAAVDLARLAGFKPAGVLIEIMSEDGSMARLPELKQIATKFNLKLISIKDLIEYRLTHESLVKREIGVDMPTNLGDFDLIAFRQISTGEVHLALIKGTWEKDEPVMVRVHSSCVTGDIFGSCRCDCGPQLHKAMEMIQQEGKGVILYMNQEGRGIGLLNKLKAYKLQEQGRDTVEANLELGFKMDQRDYGTGAQILRDLNISKLRLITNNPVKRAALAGYGLEITEAVPIEIPSNPHNLEYLKTKRDKMGHTILKKD
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: UQCC5_MOUSE
Sequence: MFSRAQVRRALQRVPGKQRFGIYRFLPFFFVLGGAMEWIMIKVRVGQETFYDVYRRKASERQYQRRLEDTSETNLHKLIK
What is the function of this protein?
Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (PubMed:35977508).  Mediates early complex III biogenesis (PubMed:35977508).  Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (PubMed:35977508).  Also required for cytochrome c oxidase complex (complex IV) assembly (By similarity).
What are the official names of this protein?
Small integral membrane protein 4, Small nucleolar RNA host gene 8.
What is the protein family that this protein belongs to?
Belongs to the UQCC5 family.
Protein: TK1C_HADVE
Sequence: AICTGADRPCAACCPCCPGTSCKAESNGVSYCRKDEP
What is the function of this protein?
This excitatory toxin inhibits insect calcium-activated potassium (KCa) channels (Slo-type).  Pan-neuronal expression in Drosophila is lethal but flies engineered to express the toxin only in clock neurons have defects in circadian rhythm but a normal lifespan.
What are the official names of this protein?
Lambda-hexatoxin-Hv1c, Lambda-HXTX-Hv1c, Janus-atracotoxin-Hv1c, Janus-AcTx-Hv1c, Kappa-atracotoxin-Hv1c, Kappa-AcTx-Hv1c, Kappa-hexatoxin-Hv1c, Kappa-HXTX-Hv1c.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 11 (kappa toxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK2_METAC
Sequence: MLRVMTSRNFLTIDDFDIRGKTILLRVDMNSPMDTQGHILDDMRIKSHIATLKDLESAKVVLLAHQSRPGKKDFTTMKPHAHLLSRYLGKQVTYVDDIFGTFAKTHIASMEDGDVIMLENVRFYSEESLERTPAEQANTYMVKKLAPFVDIFLNDAFAVAHRSHLSVVGFTEVLPSGAGRVMEKELVSLDRGVKGGERPSIFVLGGAKVDDSLRVTENVLTSGGADRVLLTGVVANVALAASGVNIGKVNMDFIKSQGYENQIEKARGLLAKFKDRIGLPKDVALNDNRERVEVHISELNSDSLPINDIGLETIVDYTNEIQNSKTVVLNGPAGVSEIEDFALGTHEIIKAAIKSDFSIIGGGHISVEVAHLGLEHRFSHISTGGGACIDYLAGEKLPGVESLKAAYIKYQEAKKL
What are the official names of this protein?
Phosphoglycerate kinase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_RHOJR
Sequence: MRLDVVTIFPEYLEPLRAALLGKAIDKGLISVEVHDLRDWTHDVHKAVDDSPYGGGPGMVMKPTVWGPALDDVLAAGDGDTDTLLVVPTPAGVPFTQATAERWAGEKRIVFACGRYEGIDQRVFDDAARRVRVEEVSIGDYVLIGGEAAVLVMTEAFVRLIPGVLGNQQSHQEDSFSDGLLEGPSYTRPATWRGLDVPPVLLSGDHAKVAAWRREQSLQRTAERRPDLLP
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_HHV1E
Sequence: MASYPGHQHASAFDQAARSRGHSNRRTALRPRRQQEATEVRPEQKMPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITIGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQGGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMIQTHVTTPGSIPTICDLARTFAREMGEAN
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: SOG_DROME
Sequence: MANKLRKSNAIEWATATGTVPLLERSCCHSEDAALEPQASKTSHREQAPILRHLSQLSHLLIIAGLLIVCLAGVTEGRRHAPLMFEESDTGRRSNRPAVTECQFGKVLRELGSTWYADLGPPFGVMYCIKCECVAIPKKRRIVARVQCRNIKNECPPAKCDDPISLPGKCCKTCPGDRNDTDVALDVPVPNEEEERNMKHYAALLTGRTSYFLKGEEMKSMYTTYNPQNVVATARFLFHKKNLYYSFYTSSRIGRPRAIQFVDDAGVILEEHQLETTLAGTLSVYQNATGKICGVWRRVPRDYKRILRDDRLHVVLLWGNKQQAELALAGKVAKYTALQTELFSSLLEAPLPDGKTDPQLAGAGGTAIVSTSSGAASSMHLTLVFNGVFGAEEYADAALSVKIELAERKEVIFDEIPRVRKPSAEINVLELSSPISIQNLRLMSRGKLLLTVESKKYPHLRIQGHIVTRASCEIFQTLLAPHSAESSTKSSGLAWVYLNTDGSLAYNIETEHVNTRDRPNISLIEEQGKRKAKLEDLTPSFNFNQAIGSVEKLGPKVLESLYAGELGVNVATEHETSLIRGRLVPRPVADARDSAEPILLKRQEHTDAQNPHAVGMAWMSIDNECNLHYEVTLNGVPAQDLQLYLEEKPIEAIGAPVTRKLLEEFNGSYLEGFFLSMPSAELIKLEMSVCYLEVHSKHSKQLLLRGKLKSTKVPGHCFPVYTDNNVPVPGDHNDNHLVNGETKCFHSGRFYNESEQWRSAQDSCQMCACLRGQSSCEVIKCPALKCKSTEQLLQRDGECCPSCVPKKEAADYSAQSSPATNATDLLQQRRGCRLGEQFHPAGASWHPFLPPNGFDTCTTCSCDPLTLEIRCPRLVCPPLQCSEKLAYRPDKKACCKICPEGKQSSSNGHKTTPNNPNVLQDQAMQRSPSHSAEEVLANGGCKVVNKVYENGQEWHPILMSHGEQKCIKCRCKDSKVNCDRKRCSRSTCQQQTRVTSKRRLFEKPDAAAPAIDECCSTQCRRSRRHHKRQPHHQQRSSS
What is the function of this protein?
Putative negative growth factor (PubMed:7958919).  Antagonist of dpp, a protein involved in patterning the dorsal region and in the development of the neuroectoderm; dpp inhibition is enhanced by tsg (PubMed:7958919).  Required for establishment of a narrow stripe of peak levels of BMP signaling in the dorsal midline of early embryos, that will give rise to the amnioserosa (PubMed:11260716).  During pupal development, plays a role in specification of the posterior crossvein in the wing (PubMed:15872004).  Exhibits both agonist and antagonist activities towards BMP signaling during pupal wing patterning (PubMed:15872004).
What are the official names of this protein?
Dorsal-ventral patterning protein Sog, Short gastrulation protein.
What is the protein family that this protein belongs to?
Belongs to the chordin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: RECO_PSEPW
Sequence: MEQPVGQPAYVLHSRAYKETSALVDFFTPQGRVRAVLRRARGKGGSLVRPFVPLEVELRGRSELKNVGRLDSMGIAAWLHGDALFSGLYLNELLMRLLPAEAPQPELFEHYALTLQALAAGRPLEPLLRSFEWRLLEDLGYAFALDHDVSDEPIEADGLYRLQVDAGLERVYLVQPGLFNGAELLALAQADWDAPGALLAAKRLMRQALAVHLGPKPLVSRELFRKR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: NDHI_GALQU
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YL279_YEAST
Sequence: MRFRSQRAVCRSRNYSMYCCSRVFVRNPRLDRRYPQVKILAKLHFFFHFFFSFLLHLISPAVTGGITRAPFLCLGPRVPLFRLERPLHAARTSRRCAGAASVSVDGATVEAPPLWTASCRTTPQVRARA
What are the official names of this protein?
Putative uncharacterized protein YLR279W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SRP19_DICDI
Sequence: MTSAQPKAVDVSTIPGFKKWYIVYPNHINSELTKEKGRKVSKEHGVKNPTLPEIAEATAQLGLPCIIETSKGYPKEFFLRGRLRINFFCDGTTMPRNPHIPNKTVLLVKIAERIKLINPNRPEPFNPISMLAPIQAVSQKEKKPAPQPTTTTTTTTTPSSSSSSSSKGGKKKKNVNVI
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  Binds directly to 7SL RNA (By similarity).  Mediates binding of srp54 to the SRP complex (By similarity).
What are the official names of this protein?
Signal recognition particle 19 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: RNPH_SOLUE
Sequence: MRTDNRTAGQLRPVQITTGCLMTAEGSALIKVGNTHVLCAATIEDTVPPFLRNTGKGWVTAEYSMLPRATAKRTPREVTKGRPSGRTHEIQRLIGRSMRSAVDMSSFGERTLIIDCDVIQADGGTRTASITGAFVAMALAFRQLIEYRALKANPIRDYVAATSVGLVGGIPMLDLCYEEDSQADVDMNVVMTGGGKFVEVQATAEHSAFDDAQMAELTELARTGIAQLVRMQKEIIEG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL18A_HUMAN
Sequence: MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIAASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L18a, Large ribosomal subunit protein eL20.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_STAA3
Sequence: MDFVNNDTRQIAKNLLGVKVIYQDTTQTYTGYIVETEAYLGLNDRAAHGYGGKITPKVTSLYKRGGTIYAHVMHTHLLINFVTKSEGIPEGVLIRAIEPEEGLSAMFRNRGKKGYEVTNGPGKWTKAFNIPRAIDGATLNDCRLSIDTKNRKYPKDIIASPRIGIPNKGDWTHKSLRYTVKGNPFVSRMRKSDCMFPEDTWK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RS10_LEGPH
Sequence: MSSNQNIKIRLKSFDHRLIDLSTREIVDTAKRTGAQIRGPIPLPIRKEKFTVLTSPHVNKDARDQYELRTHKRLVVIVHPTEKTVDALMKLDLAAGVDVQISLDD
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LQK1_HUMAN
Sequence: MARGLLHLRVGGRRPRGLCCWKKGSRSRPQERVLGSTSGKNWRRVTERSEGSKFIGIYSVRECKSSDCRRRNSRPSVVSLLRGSCEEL
What are the official names of this protein?
Putative uncharacterized protein LQK1, FLVCR1 antisense RNA 1, FLVCR1 divergent transcript.
Protein: TRMD_BURO0
Sequence: MNQVTESAVQFDVVTLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLARPLEAAIDAAKAAQAEQGIASTRVVMMSPQGAPLTHDRAVRMAQEPGVVVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDSLSAVQDSFADGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEKWRRQEALRNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKDAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
Protein: RL30_BARHE
Sequence: MVQKKSQSSKTVTVEQIGSPIRNSQIQRATLKGLGLNKMHRRRVLEDTLCVRGMIAKVQHLVRVIDES
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y533_STRP6
Sequence: MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRKLGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPDLLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN
What are the official names of this protein?
Putative phosphatase M6_Spy0533.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: CMTR2_DROME
Sequence: MSFRSSPQGKPHPMTDYQSIRPSEVEQLFEKKFHYQKPKGNKSWQLPPPDQALFSEFYQFEALQGLREQLNAVKSKLNDYGVQEWSAHTNRRDPSGEVSWRLKNDTKAEFVTVAWCKLFECLHRYPLVTKPAVNSMHLCEAPGAFIASLNHYLHSKYEKDEIKWRWRSTTLNPYYEGNAINQMISDDRFIVHTLDNWFFHKDLTGNLLDVANIDHLVERCEVEFQGQVDLVTADGSIDCAAQPDCQEEIVVRLFFAEVLSALRILSSGGNFLVKMFTLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLNYNKDHPDLPRLLEEIKSKLAQPNDTLVMPLFAKFQIPHDFLMQHEIACRMYMKLQTDAIEGSIYAYESNDRHYLRHLHHLRSLVANTYYSLYKVKPLEDSLCIVDKEATSKALGFQVPVYGGSYTERESLKHGDLLKQIYCLRREFNQLEKCLNNRTPYSYVKNRTAPLNLHISRGAPVQSLQSSMFASEPILILRLRILDTFELDPVWQSAPKCQLESKTLCYLPPTEDEAFHTAQQRFFIDLLEEVKKLKPDSIVFHKFLFLTHYAASLLLFLIESVYQDCCFNSNQAQTLTLSKLKDTANSALEQVLELLKDEQAGAIHSLLDIKELQKNQFSKALIQHNNSIVMTCFRSMLGEESFPMPVAPTSNSDVGSIQESAAVF
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs.  May methylate the ribose of the second nucleotide of a m(7)GpppG-capped mRNA (cap0) to produce m(7)GpppRmpNm (cap2) (By similarity).  Regulates expression of tracheal genes required for pathfinding on the segmental nerve (PubMed:10068643).
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2, Cap methyltransferase 2 homolog, Cap2 2'O-ribose methyltransferase 2 homolog, MTr2, FtsJ methyltransferase domain-containing protein 1 homolog, Protein Adrift.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPE_STAAM
Sequence: MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RNH2_RHIEC
Sequence: MKRRTPPDSPLLFDTVPLVPDFKLELKARKAGHWPVAGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAIPASYVLTDGLDVPPGLDCPGQAVVKGDARSVSIAAASIVAKVTRDRMMARAHNVFPDYGFAAHAGYGTAQHRAGIEKHGPCSLHRMSFRPLRKGEDGPEMDELIPE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALRL_DANRE
Sequence: MTASCWTICLFLLGSVTEFIVLASPEVNESQQQHPQNVYHDIGVTRNKIVTAQFECYQKIMKDNSQDRRGPVCNRTWDGWLCWDDTEAGITSEQHCPDYFQDFDPTEMVTKICTESGQWFLHPESNRTWTNFTRCNLHTTEGRRTAMNLFYLALIGHGLSLTSLFISLGIFFHFKSLSCQRITLHKNLFFSFVLNSIITIIWLTAVANNQELVQQNPISCKISQFIHLYIFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYLLGWGFPLIPATIHAVARSYYYNDNCWISSNTSLLYIIHGPICAAMLVNLFFLLNIVRVLITKLKVTHQAKSSLYMKAVRATLILVPLLGIQYVLLPYKPSGRVSAEIYDYIMHILMHYQGLLVATIFCFFNGEVQAVLRRHWNQYRIQFGSTITQSDALRSASYTASSITEVQGCYSIDGHTEHLNGKNYHDFDNAIIKPENPFA
What is the function of this protein?
Receptor for calcitonin-gene-related peptide (CGRP) (By similarity).  Receptor specificity may be modulated by accessory proteins.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SGCA_HUMAN
Sequence: MAETLFWTPLLVVLLAGLGDTEAQQTTLHPLVGRVFVHTLDHETFLSLPEHVAVPPAVHITYHAHLQGHPDLPRWLRYTQRSPHHPGFLYGSATPEDRGLQVIEVTAYNRDSFDTTRQRLVLEIGDPEGPLLPYQAEFLVRSHDAEEVLPSTPASRFLSALGGLWEPGELQLLNVTSALDRGGRVPLPIEGRKEGVYIKVGSASPFSTCLKMVASPDSHARCAQGQPPLLSCYDTLAPHFRVDWCNVTLVDKSVPEPADEVPTPGDGILEHDPFFCPPTEAPDRDFLVDALVTLLVPLLVALLLTLLLAYVMCCRREGRLKRDLATSDIQMVHHCTIHGNTEELRQMAASREVPRPLSTLPMFNVHTGERLPPRVDSAQVPLILDQH
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan alpha/epsilon family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type I membrane protein. Cytoplasm, cytoskeleton.
Protein: LEU1_STAAS
Sequence: MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIEAGFPASSTGSFKSVQAIAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIATSPIHLEHKLKMSQEDVLASIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVDAGATVINIPDTVGYSYHDEYAHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAIEGGARRIEGTVNGIGERAGNAALEEVALALYVRNDHYGAQTALNLEETKKTSDLISRYAGIRVPRNKAIVGQNAFSHESGIHQDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGKHAFSEKLKALGYGIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKLETLQLQYVSSGLQSAVVVVKDKEGHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYRINSVTEGTDAQAEVHVNLLIEGKTVNGFGIDHDILQASCKAYVEAHAKFAAENVEKVGN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: YMAB_BACSU
Sequence: MGKMDEMILVAPRDDVFKKESLTFQGVYSEDSRVAEIMAQIEAAYREMRRGDAEEDPRFKQPIPYVVIKREDEVFLYERLAGGGESRLHNKLSLGFGGHMNAIEGAASFAEVLKLNTDRELEEELQINEEDKQAIVTLGLINDDENSVGKVHIGILSALQLKPGAQVEVKEKEQIAGKWMKVSELKQDDIYNRLETWSQFVVDILE
What are the official names of this protein?
Protein YmaB.
Protein: DNLJ_STRSV
Sequence: MKERMSELVELLNRYAHEYYTADRPSVSDSEYDRLYRELAELEEKYPTDILPDSPTHRVGGKILEGFEKYPHQYPLFSLQDAFSREELLAFDQRVRKEFPQVSYLCELKIDGLSISLTYENGILVAGATRGDGSVGENITENLKRVKDIPLTLKEPLDITVRGECYMPKASFDAVNQLRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPTQVGSQEEVLNKLADLDFSVNPTHILADSIESVWEFIEKIAEERDSLPYEIDGIVIKVNDLAVQEELGFTVKAPKWAIAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRQKDTVIVYKAGDIIPAVLRVVESKRVSEEALEVPSHCPSCESELVHFEDEVALRCINPLCPAQIKEGLIHFASRDAMNITGLGPAVVEKLFAQNLVKDVAGIYRLTIENLLELENFKEKSANKLYTAIQASKKNSAERLLFGLGIRHVGSKASRILLEKFHDIPRLSQASQEEIAAIDSLGTVIAQSLHTYFEQEGSQILLAELQEAGVNLDYLGQKAAADAALSGMTVVLTGKLQKLTRNQAKEKLQSLGANVSGSVSKKTDLVVAGADAGSKLAKAQELGIEIRDEDWLDSL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.