PharMolix/UniProtQA huggingface dataset:
Protein: HUTI_BACAN
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1693_FRAT1
Sequence: MIIVISPAKSQNFEPIKTAYQFTQPIFKQQIIKLINTLKYYEVEEIEKLMKISPKLAEEVFAKHNSFNPNKYDNSNAKAAIFTFSGDVYKGLEADTLDNKTIEYAQNHLLMLSGLYGLVRPLDLIQAYRLEMGTNIKIDGKILHKYWQDKITTQLNEYFSQQQNKILINLASNEYSQAIDKKSLAVKWLDIDFKENKAGAYKTIGIHAKKARGLMTRYILENRIENVSDIKKFNVAGYQFNPDFSDENLLCFTR
What are the official names of this protein?
UPF0246 protein FTF1693c.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: KHSE_BURMS
Sequence: MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFENLTAGQLPFYVDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAQLAPGVEHCVEVGQMLARMHLAGRDYPRHQPNLRSLPWWRDTVPAIAPFVTGEQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAEPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLPTGALDAARADALLRAYQTVRPFTAGERRRWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAHAGALPETHACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: AMGO3_HUMAN
Sequence: MTWLVLLGTLLCMLRVGLGTPDSEGFPPRALHNCPYKCICAADLLSCTGLGLQDVPAELPAATADLDLSHNALQRLRPGWLAPLFQLRALHLDHNELDALGRGVFVNASGLRLLDLSSNTLRALGRHDLDGLGALEKLLLFNNRLVHLDEHAFHGLRALSHLYLGCNELASFSFDHLHGLSATHLLTLDLSSNRLGHISVPELAALPAFLKNGLYLHNNPLPCDCRLYHLLQRWHQRGLSAVRDFAREYVCLAFKVPASRVRFFQHSRVFENCSSAPALGLERPEEHLYALVGRSLRLYCNTSVPAMRIAWVSPQQELLRAPGSRDGSIAVLADGSLAIGNVQEQHAGLFVCLATGPRLHHNQTHEYNVSVHFPRPEPEAFNTGFTTLLGCAVGLVLVLLYLFAPPCRCCRRACRCRRWPQTPSPLQELSAQSSVLSTTPPDAPSRKASVHKHVVFLEPGRRGLNGRVQLAVAEEFDLYNPGGLQLKAGSESASSIGSEGPMTT
What is the function of this protein?
May mediate heterophilic cell-cell interaction.  May contribute to signal transduction through its intracellular domain (By similarity).
What are the official names of this protein?
Amphoterin-induced protein 3, AMIGO-3, Alivin-3.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. AMIGO family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RPOZ_RHIL3
Sequence: MARVTVEDCIDKVENRFELVLLASHRARLISQGASITIDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEPDPASMIAAGGVAAADGEEQDDVPETITFDQMSEEELLAGIEGLVPPEKSDDY
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS13_NOCFA
Sequence: MARLMGVDLPREKRMEIALTYIYGIGRTRSKEILEATGVSPDLRSKDLSDDDLTKLRDYIEASEFKVEGDLRREVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PYRC_PSEPF
Sequence: MSDRLTLLRPDDWHIHLRDGAVLTNTVADVARTFGRAIIMPNLVPPVRNAAEADGYRQRILAARPAGSRFEPLMVLYLTDRTQPEEIREAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPVLEAMAEAGMPLLIHGEVTRGDVDVFDREKIFIDEHMRRVVERFPTLKVVFEHITTGDAVQFVNEASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAATSGSAKFFLGTDSAPHAQHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEAFASLNGPRFYGLPANTDRITLVRDEWTAPTSLPFGELTVIPLRAGEKLRWRLLEEHA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RS3_DINSH
Sequence: MGNKVNPIGMRLQVNRTWDSRWYADTKDYGDLLLEDLKIREFIKEECKQAGISRVIIERPHKKCRVTIHTARPGVIIGKKGADIEGLRRKIAAMTDSELHLNIVEVRKPELDAALVGESIAQQLERRVSFRRAMKRAVQNAVRMGAQGIRVNLAGRLGGAEIARTEWYREGRVPLHTLRADIDFANVEATTAYGIIGIKVWIFKGEIMEHDPQARDRRHAELQEGGGPRPQGGGRPRRDR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GATD_STAAN
Sequence: MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
What is the function of this protein?
The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide (PubMed:22291598, PubMed:30154570).  The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia.  The resulting ammonia molecule is channeled to the active site of MurT (PubMed:22291598).
What are the official names of this protein?
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit GatD, Lipid II isoglutaminyl synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. GatD subfamily.
Protein: FTHS_ROSDO
Sequence: MAYKSDIEIAREAKKRPIQEIGEKIGIGSDDLLPYGHDKAKVSQSFINSVQDKPNGRLVLVTAINPTPAGEGKTTTTVGLGDGLNHIGKNAMICIREASLGPNFGMKGGAAGGGYAQVVPMEDMNLHFTGDFHAITSAHSLLSAMIDNHIYWGNEAEIDVRRVQWRRVVDMNDRALRQITASLGGVANGFPREAGFDITVASEVMAILCLAKDLKDLEKRLGDMIVAYRRDRSPVFCRDIKAQGAMTVLLKDAMQPNLVQTLENNPAFVHGGPFANIAHGCNSVIATTTALKLADYVVTEAGFGADLGAEKFMNIKCRKAGIAPSVVVCVATVRAMKMNGGVAKADLGAENVDAVKKGCPNLGRHIENLKSFGVPVIVAINHFVTDTDAEVEAIKSYVSEHGAEAVLSRHWELGSEGSADLARKVVEVAEKDSANFAPIYPDDMPLAEKVQTIAKRIYRADEALMDKKVRDQLKLWEEQGYGHLPVCMAKTQYSFSTDPNLRGAPTGHSVPVREVRLSAGAGFVVVVCGEIMTMPGLPRVPSAENIHLNEDGQIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: EFTS_RICCN
Sequence: MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAAAAKKAGRIASEGLTAAKVDGLTGVVIEVNSETDFVARNEQFQDLVKDIANLAVIAKTIDTLKTFKMQSGKSVEEEIIENIATIGENLTLRRMDILEISEGAIGSYVHNEVVPNLGKISVLVGLASNAKDKAKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIAKMVEGRIRKFFSEVVLLQQNFLFEPKLTVAEVIKNAEKELGAEIKIAKFIRYELGEGIEHEEKNFADEVAAITQG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_BACC7
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLAEARKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ERPA_SALCH
Sequence: MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: IOLA2_BACMK
Sequence: MKNVQTLKNYIGGQWIESTSKQVEDVPNPATGEIIARVPLSTKEDLDRAVATAKEAFKTWRKVAVPRRARILFRYQQLLIENWEGLAKLVTLENGKSYKEAYGEVQRGIECVEFAAGAPTLMMGEQLPDIATGVESGMYRYPIGVIAGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPLLANRIAELFKEAGLPDGVLNIVHGAHDVVNGILDNEDVKAVSFVGSQPVAEYIYKTAAANGKRVQALAGAKNHSIVLKDADLSSTVKEITSAAFGSAGERCMAAAVVVVEEDVADELVNRLLQEANAITIGNGLEEGVFLGPVIREGHKERTLGYIQSGVEQGATLIRDGREDDIANSQGYFVGPTIFDNVTQEMKIWQDEIFAPVLSIVRVKDLMEAIHVANASPFANGACLYTNSAKAIREFREEIDAGMLGVNLGVPAPMAFFPFSGYKKSFYGDLHANGKDGVEFYTRKKMLTARY
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 2, MSA dehydrogenase 2, Methylmalonate-semialdehyde dehydrogenase 2, MMSA dehydrogenase 2, MSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: PNCB_PSYIN
Sequence: MSIKKLDYWLIESLMDTDLYKITMLQAYYHAPEFRLVDIEWKFACRNRNGLDLSILIPEIFRQLEHLCTLSFSDAELDYLAGFSFIKPDFIEFLRIFRLDMRFVHIEAKGEDISLRFSGPLLHVSLLEIYTLAIISELHTFVNCGGIDLKVARERLAEKIAYLKAEDDLSGFSFADFGTRRRASKAWHEEVLLTLKEQLPASFSGTSSLHFARTLGLPPIGTMAHEWFQSWQAVTRLADAQKAALEGWVQEYRGRLGIALTDCYSMDSFIRDFSDPYFGKLYDGLRHDSGCPFVWAEKAILMYQQMGIDPLSKTLVFSDGLNFPRMLEIWKRFKGRAKISFGIGTNLTNDVGNVPLNIVIKMIAANGRPIAKISDEPGKSMCEDLGYLQYLASQYGIDPSLVKISQ
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: YBEY_YERPS
Sequence: MSQVILDLQIACADSQGLPTEGDFQRWLEAVLPLFQPVSEVTIRLVDEAESHDLNLTYRGKDKSTNVLSFPFEAPPEIELPLLGDLIICRQVVEKEAIEQEKALLAHWAHMVVHGSLHLLGYDHIDDDEAEEMELIETEIMHGLGYPDPYISEKDPD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTFLB_ECOLI
Sequence: MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQGSSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSELPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFGLPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLANDKALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVLTYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSLLEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAIPYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLAIGLALNISFIIVLKGLWLRRKAKAAQQELVHEH
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FrvAB PTS system is involved in fructose transport.
What are the official names of this protein?
Fructose-like PTS system EIIBC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y615_AQUAE
Sequence: MKKALFLVGLVFTAGVISSCGGVSSQRTYEGAAVGAAVGAAAGVLLDKENRWRGGVIGAALGAILGGTITEIAQRAAKEAAQNNKPVVYRAEDGSQMVRAEPVEKRGNCTLVKTKYYQNGKLVKVEEKEVCE
What are the official names of this protein?
Uncharacterized lipoprotein aq_615.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y1246_HAEIN
Sequence: MLVVFTMKKAHSPLFPIFTFVLINLIILSLSRLGLAVWQSERVSAVDGWLQLFLQGVRMDVVALCYLFGVPALLTTLFHSSKVWVKILRLWLTFGSVFIIFMEIATPAFIETYDYRPNRLFIEYLIYPKEVFSMLAEGHLSAVIFSLVFTILAAVIYWKISGWAVKNLRSMSWKLRPVIALLVIVVSFLGARSSFQHRGINPAMVAFSSDALVNSLVLNSGYSVIYAAQQFKDEEKSSEMYGKMDADEMFRIVKASRGRPESDYISDKYPTLTKNVATYQGKPKNIVILLQESLGAQFIGTLGGKPLSPNVDQLAKEGWLFENLYATGTRSVRGIEATTAGFTPTPARAVVKLNNAQSGFFTIADLLHKQGYNTSFIYGGEKHFDNMASFFYGNGFKDIWDQQDYQNPKFTGTWGVSDEDLFDKANETFTKLQNEGKPFFSLVFSSSNHDPFEYPDGKIELYEQPKATRNNAAKYADYALGHFFKMAKQSNYWKDTIFLIIADHDSRVGGASLVPIKHFHIPALILGDGITPRRDSRLVSQIDMPTTLLSLAGVSGNYPMIGFDLTQDVNPDRAFMQYDQTQAMMKGNNDVVIQMPNKAAQGYHYDKSTETLTPKDVPDAMKKEALAHALLGSYLYKNRLYSSGENK
What are the official names of this protein?
Uncharacterized protein HI_1246.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URK_SALSV
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB_PSEAB
Sequence: MENATHPVPLIELRDIRKRYGGNGTPEVEVLKGVSLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPSSGSYHFAGHDVAELDSDEQAWLRREAFGFVFQGYHLIPSASAQENVEMPAIYAGIPASERHTRARALLERLGLAERTANRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDRDVAARAKRIIEVRDGEIVSDSANDERPAQPSAGVERHLQADDLSQRLAEGSSEPSGAWRAELLEAVRAAWRVMWINRFRTALTLLGIIIGVASVVVMLAVGEGSKRQVMAQMGAFGSNIIYLSGYSPNPRAPMGIVSSDDVAAIATLPQVKKVMPVNGGELVVRYGNIDYHAYVGGNNTDFPEILNWPVAEGSYFTERDEDAATTVAVIGYKVRKKLFGSANPIGRYILIENVPFQVIGVLAEKGSSSGDKDADNRIAIPYSAASIRLFGTRNPEYVIIAAADAQRVHQAERAIDQLMLRLHRGQRDYELTNNAAMIQAEAKTQNTLSLMLGSIAAISLLVGGIGVMNIMLMTVRERTREIGIRMATGARQGDILRQFLTEAAMLSVVGGLAGIALALCIGGVLLLGQVAVAFSLSAIVGAFSCALVTGLVFGFMPARKAAQLDPVAALASQ
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASTD_SHEB2
Sequence: MTHYIQGQWHAGKGHDVASMNPANTHTIWTGKTATAEQVNAAVDAARAAQFDWFMLGFDARLAIVETYRSQLEANKAELAETIAQETGKPQWETATEVGAMIGKIALSAAAYNKRTGTEANDTPAGRAVIRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVIFKPSELTPKVAELMVSLWDKAGLPAGVLNLVQGEVDTGKALASHPQLDGLFFTGSSRTGHFLHQQYAGHPGKILALEMGGNNPLIIKGVQDIKAAVHDILQSAYISSGQRCTCARRLYVEQGEQGDALIAMLADAVKQIKVGPWNSQPQPFMGSMISETAAKGMVAAQANLLNLGGVSLVELTHLEAGTGLVSPGLIDVTAIDALPDEEYFGPLLQLVRYSDFDQAIKLANQTRYGLSAGLLADSREDYDYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADTVSLPATLSPGLSL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: PLPP6_MOUSE
Sequence: MPSPRRTIEGRPLGSSGGSSVPGSPAHGGGSGGGRFEFQSLLNCRAGADPACARLRASDSPVHRRGSFPLAASGPAQAAPAPPPEDARMNLNPSFLGIALRSLLAIDLWLSKKLGVCAGESSAWGSVRPLMKLLEISGHGIPWLLGTLYCLLRSDSWAGREVLMNLLFALLLDLLLVAVIKGLVRRRRPAHNQKDMFFTLSVDRYSFPSGHATRAALVSRFILNHLVLAIPLRVLVVLWAFVLGLSRVMLGRHNVTDVAFGFFLGYMQYSIVDYCWLSPHNVPVLFVLWNQQ
What is the function of this protein?
Magnesium-independent polyisoprenoid diphosphatase that catalyzes the sequential dephosphorylation of presqualene, farnesyl, geranyl and geranylgeranyl diphosphates.  Functions in the innate immune response through the dephosphorylation of presqualene diphosphate which acts as a potent inhibitor of the signaling pathways contributing to polymorphonuclear neutrophils activation.  May regulate the biosynthesis of cholesterol and related sterols by dephosphorylating presqualene and farnesyl diphosphate, two key intermediates in this biosynthetic pathway.  May also play a role in protein prenylation by acting on farnesyl diphosphate and its derivative geranylgeranyl diphosphate, two precursors for the addition of isoprenoid anchors to membrane proteins.  Has a lower activity towards phosphatidic acid (PA), but through phosphatidic acid dephosphorylation may participate in the biosynthesis of phospholipids and triacylglycerols.  May also act on ceramide-1-P, lysophosphatidic acid (LPA) and sphing-4-enine 1-phosphate/sphingosine-1-phosphate.
What are the official names of this protein?
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6, Phospholipid phosphatase 6.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope. Nucleus inner membrane.
Protein: Y3382_XANCP
Sequence: MRIGIVVDSACDLPQDFIQRNNVIVLPISVRIGEAVLADHRDEEATLSFLHAHVAERGHEAETTPFSVNQIRDLFLQRLVIDYDHVFCLTISKLRSQIFDNATQASFAILNDYKPVRQAAGHTSPFALRVIDTLNLFAGQGITAVEAVRLRAQGLGVAPIRARLEQLAEHTYGYMIPRDLYYLRARARTKGDRSVGLIGAALGSALDIKPVLRAYRGVTEPVAKLKGFEPSAEKLFAFTVRKLREGLMTPTVCVGYGGELAELHALPGYAALQAACQTQGVELFESVMSLTGMVNVGKGALAVAFAAEPHSFSA
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein XCC3382.
Protein: FH19_ARATH
Sequence: MSLVDISGAYSLVPLPPPPPPLMRRRAPLPPPPPPPLMRRRAPPPPPPPLMRRRAPPPPPPPPLPRPCSRPPKTKCSLKPLHWVKKTRALPGSLWDELQRRQECRDIEDEQILCAIELSVSEIETIFSLGAKPKPKPEPEKVPLIDLRRATNTEIRLMLLNIRLPDMIAAAMAMDESRLDDFDQIENLINLFPTKEDMKFLLTYTGDKGNCEQLFQYLQEVVKVPRVESKLRVFSFKIQFGTQITKLTKGLNAVNSACEEIRTSQKLKDIMENILCLGNILNQGTGRGRAVGFRLDSLLILSETRADNSKMTLMHYLCKVLASKASDLLDFHKDLESLESASKIQLKSLAEEIQAITKGLEKLKQELTASETDGPVSQVFRKLLKEFISNAETQVATVMALYYPARGNAEALAHYFGYHYPFEQVTATLLSFIRLFKKAHEENVKQAELEKKKAAKEAEMEKTK
What are the official names of this protein?
Formin-like protein 19, AtFH19.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-II subfamily.
Protein: CH602_BURCH
Sequence: MAAKEILFSDIARSKLTEGVNILANAVKVTLGPKGRNVVLERSFGAPVVTKDGVSVAKEIELADKLQNIGAQLVKEVASRTSDAAGDGTTTATVLAQAIVREGQKYVAAGLNPLDLKRGIDKAVASAVEELKKISKPTTTSKEIAQVATISANGEESIGQRIAEAIDRVGKEGVITVEDGKSLADELDVVEGLQFDRGYLSPYFINNPDKQIAEIESPYILLHDKKISNIRDLLPVLEQVAKSGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKALLEDIAILTGGQVIAEETGLTLEKTTLAELGQAKRIEVGKENTTVIDGAGDAKNIEARVKQIRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGGATEIEVKEKKDRVDDALHATRAAVEEGIVPGGGVALIRVRQAIRELKGANADQDAGIKIVLRALEEPLRQIVTNAGEEASVVVAKVAEGTGNFGYNAQTGEYGDLVESGVLDPTKVTRTALQNAASVAGLLLTTDATVYEAPKDAAPAAAPGGPGAGGPGFDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGR_BACSU
Sequence: MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSFHKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGDKGAPQTIELEAKVIMRKSL
What is the function of this protein?
Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization.
What are the official names of this protein?
HTH-type transcriptional regulator KdgR, Kdg operon repressor.
Protein: ATPF1_RHOPS
Sequence: MGIFAEAETWVAVAFVILMALFAYLGVHRTVLQALDNRRARIKAELDEARKLKDEAAKLLADYRARRAQAEREAEAIISSAKADAERIAAESKAKLEDFVARRTKTAESKIALAEAQAVADVRAAAAEAAVSAAATILSQSVKGQVADDLLGKGIQEVRSKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CARB_STRCO
Sequence: MPKRTDIQSVLVIGSGPIVIGQAAEFDYSGTQACRVLKAEGLRVVLVNSNPATIMTDPEIADATYVEPITPEFVEKIIAKERPDALLPTLGGQTALNTAISLHGNGVLEKYGVELIGANVEAINKGEDRDLFKEVVEEVRKKIGHGESARSYICHSMDDVLKGVDALGGYPVVVRPSFTMGGAGSGFAHDEDELRRIAGQGLTLSPTTEVLLEESILGWKEYELELMRDKNDNVVVVCSIENFDPMGVHTGDSITVAPAMTLTDREYQTLRDVGIAIIREVGVDTGGCNIQFAVNPEDGRVIVIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDEIPNDITQETPASFEPTLDYVVVKAPRFAFEKFPSADSTLTTTMKSVGEAMAIGRNFTEAFQKALRSLEKKGSQFTFVGEPGDKDELLREAVRPTDGRINAVMQAIRAGATPEEVFDATKIDPWFVDQLFLIKEIADEIAESRELTADLLTEAKRHGFSDQQIAEISGLGEDVVRQVRHALGVRPVYKTVDTCAAEFAARTPYFYSSYDEESEVAPREKPAVIILGSGPNRIGQGIEFDYSCVHASFALSDAGYETVMVNCNPETVSTDYDTSDRLYFEPLTLEDVLEIVHAEQQAGPVAGVIVQLGGQTPLGLSQALKDNGVPVVGTSPEAIHAAEDRGAFGRVLAEAGLPAPKHGTATTFGEAKAIADEIGYPVLVRPSYVLGGRGMEIVYDETRLEAYIAESTEISPSRPVLVDRFLDDAIEIDVDALYDGEELYLGGVMEHIEEAGIHSGDSACALPPITLGGFDIKRLRASTEGIAKGVGVRGLINIQFALAGDILYVLEANPRASRTVPFTSKATAVPLAKAAARISLGATIAELRAEGLLPALGDGGTLPLDAPISVKEAVMPWSRFRDIHGRGVDTVLGPEMRSTGEVMGIDSVFGTAYAKSQAGAYGPLPTKGRAFISVANRDKRSMIFPARELVAHGFELMATSGTAEVLKRNGINATVVRKQSEGTGPNGEKTIVQLIHDGEVDLIVNTPYGTSGRLDGYDIRTAAVARSVPCLTTVQALAAAVQGIDALNHGDVGVRSLQEHAAFLIAARD
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MIAB_BACC7
Sequence: MNEQQRLASQQVNSSTKKEEKDYSKYFESVYQPPSLKDAKKRGKEEVKIERDFGLPEEFRNFGTGRKFYIRTYGCQMNEHDTEVMAGIFTALGYEPTFSTEEADVVLLNTCAIRENAENKVFGELGHLKALKRRNPDLLIGVCGCMSQEESVVNKIMQKNQHVDMVFGTHNIHRLPYILKDAMFSKETVVEVWSKEGDVIENLPKVRRGDIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEIRHLAANGYKEITLLGQNVNAYGKDFEDIEYGLGDLMDELRKVDIARIRFTTSHPRDFDDHLIEVLGKGGNLVEHIHLPVQSGSTEMLKIMARKYSREHYLELVRKIKEAIPNAVLTTDIIVGFPNETDEQFEETMSLYREVGFDTAFTFIYSPREGTPAAKMKDNVPMEVKKERLQRLNALVNKLAIEKNNRYKGQIVEVLVDGESKNNPEVLAGYTRTNKLVNFVAPKSLIGQLVKVKVTDAKTWSLNGELVEEPIEVE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.