PharMolix/UniProtQA huggingface dataset:
Protein: FUT1_ARATH
Sequence: MDQNSYRRRSSPIRTTTGGSKSVNFSELLQMKYLSSGTMKLTRTFTTCLIVFSVLVAFSMIFHQHPSDSNRIMGFAEARVLDAGVFPNVTNINSDKLLGGLLASGFDEDSCLSRYQSVHYRKPSPYKPSSYLISKLRNYEKLHKRCGPGTESYKKALKQLDQEHIDGDGECKYVVWISFSGLGNRILSLASVFLYALLTDRVLLVDRGKDMDDLFCEPFLGMSWLLPLDFPMTDQFDGLNQESSRCYGYMVKNQVIDTEGTLSHLYLHLVHDYGDHDKMFFCEGDQTFIGKVPWLIVKTDNYFVPSLWLIPGFDDELNKLFPQKATVFHHLGRYLFHPTNQVWGLVTRYYEAYLSHADEKIGIQVRVFDEDPGPFQHVMDQISSCTQKEKLLPEVDTLVERSRHVNTPKHKAVLVTSLNAGYAENLKSMYWEYPTSTGEIIGVHQPSQEGYQQTEKKMHNGKALAEMYLLSLTDNLVTSAWSTFGYVAQGLGGLKPWILYRPENRTTPDPSCGRAMSMEPCFHSPPFYDCKAKTGIDTGTLVPHVRHCEDISWGLKLV
What is the function of this protein?
Involved in cell wall biosynthesis.  Is both necessary and sufficient for the addition of the terminal fucosyl residue on xyloglucan side chains, but is not involved in the fucosylation of other cell wall components (PubMed:10373113, PubMed:11743104, PubMed:11854459, PubMed:14730072).  Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066).
What are the official names of this protein?
Galactoside 2-alpha-L-fucosyltransferase, Xyloglucan alpha-(1,2)-fucosyltransferase, AtFUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 37 family.
Protein: AROE_SHIF8
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFRAGGKGANVTVPFKEEAFARADELTERAALSGAVNTLKRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PPK_LOCMI
Sequence: DGGEPAAPLWFGPRV
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin, Capa-Pk, Lom-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_PYRAR
Sequence: MNPYLILLKPRVIWLLILASLAGYLYSARQPNIAQAFSLLLVAFLSTGGAAAFNHYWERDIDAAMRRTAKRPLPAGLVEPRNALAYSLVLSALGIALGFLLLGPLPGLFVFLGWFFYAVVYTVILKKRTWLNILGGGFAGNATFLGGYALGAGTVDLHAVLISFAIYLWIPSHIWALAYKYRDDYRRAGVPMLPTVVGEKAAVAIISLLNLASAAYIMTLYLAFGGGLLGGALVAAGVVATIATGAYALATKTDEAMWKMYKASSPVLTLFLLALIANA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVD_ROSCS
Sequence: MSSDLKRHSRTITDGRTRAGARAMLKAIGFTDEDLAKPIIGIANTWIETMPCNINLRALAARVKEGVRAAGGTPMEFNTVAISDGVTMGTEGMKASLISRDLIADSIELMGRGYMFDAIIALVACDKTIPGAAMGLTRLNVPGFLLYGGSIAPGHWRGKEITIQHVYEAIGAVAAGKMTDEELKEIEDAACPGPGACGGQYTANTMATVMEIIGLSPIGTAAVPAADPRKDSVGYRAGQLIMDVLRRDLKPRDILTRAAFENAIASVALTGGSTNAVLHLLALAREAGVPLTLDDFDTISRRTPLCCDLMPSGKYSAIHVDQAGGIQVIAKRLVDGGFAHGDAITVTGRTLAEEAADAVETPGQDVIRPLDNPIKPTGGLLVLRGNLAPEGSVVKLFGYERTYHRGPARVFDSEEAAMAAIVGGEIRPDDIVVIRYEGPRGGPGMREMLGVTSAIVGAGLGQSVSLVTDGRFSGATRGVMIGHVAPEAARGGPLAIVQEGDEIEINLDERRVDLVLSEEEIADRLLAWQPPAPRFEWGVMARYSALVSSASEGAVLVTP
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GLUC_SCYCA
Sequence: HSEGTFTSDYSKYMDNRRAKDFVQWLMSTKRNGHAEGTYTSDVDSLSDYFKAKRFVDSLKSY
What is the function of this protein?
Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level.
What are the official names of this protein?
Glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAJ_CHAVU
Sequence: MQDVKTYLSTAPVLATLWFGLLAGILIEINRFFPDALVLPY
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CH10_SHIB3
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: ASTD_ERWT9
Sequence: MTHCINGQWLAGEGETVIKTDPVSGEVLWQGRGASAAQVAAACEAARGAFPAWARQPFAERQAIVEKFAALLDTNRVELSEAIARETGKPRWETQTEVQAMINKVAISLRAWHVRCPEQVEGESSVRHRPHGVMAVFGPYNFPGHLPNGHIVPALLAGNCVLFKPSELTPLTAEIAMRLWNHAGLPQGVLHLLQGGRETGQALVQQPQVDGILFTGSAATGYQLHRQLAGQPEKMLALEMGGNNALIVEDPDDIDAAVHIAIQSAFISAGQRCTCARRLLVRRGAAGDAFLARLAAVAATIRVGRWNDEPQPFMGSVISPQAAEKIYAEWQARIDAGGNVLLPMCWPERSSALLTPGIIDVTEVRDLPDEEIFGPLLQVMRYDDFTHAIQLANDTRYGLACGLISPQREKFDRLLVEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLASADLSLPDTLSPGLDFSVNKEAE
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: DAPB_METJA
Sequence: MIKVAVTGALGRMGSNIIKTITQQEDMKVVCAFEVPNHPKKGEDVGELIGIGKIGVPLSTADELDKVLKETKPDVLVDFTIAHACVENVKIAAKNGVNLVIGTTGFTEEQKAEIEKAIKENNVAAVISQNFAIGVNIFFKTLEFLAKKLGDYDIEIIEMHHRYKKDAPSGTALRAAEIIKANRGIESVFVYGRYGMTGERKKEEIGIHALRGGDVVGDHTVIFAGDGERIELTHRASSRQAFVNGVILAIRYIADKKEGIYNTFDVLGLNEIKF
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_HAMD5
Sequence: MLIFKICFYRLLPLSVLLLAACSALKAPESSSVLKNHIASDEWQEYQHQLKQIQQFQIQGSVAYFSDEKKAYARFFWQQYSPKNYHLLLLSPLGQTEFELKVTNGRVDMAKYKDQGEIKGDAEEILFKLTGIPIPLEHLSRWIVGASSDADEIILNRQSRLKTLIHHKKEQTWKVYYQAYNTKITPILPERLELYLISPNHQDQRMTLKINHWILK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ASP3_TOXGO
Sequence: MEGRTTAGRATPAGFWLFSCCLASVLWSANALIPAGKSAGSSFLAATSSQSSEEAPREFPGHLSNSQIASETGSALKIEEIASSGSAPEVSGAAGASASKTSEKPIRPYHTGPSSRSSAYSASSGIPLCHTCSSFDAANGGCRLCVHGEVASDFLMPMMPIRNIDTHREETLSRLEANHRTHLNEKKNFYVLRGKGPFGSLGNLPGTPGLDAAIAFGLSSPDLPSASFAQIKNKDSSDSGDVAAVGEETDSAVADGSKTLDLDLKLAETSVPILQMKDSQYVGVIGIGTPPQFVQPIFDTGSTNLWVVGSKCTDDTCTKVTRFDPSASKTFRAANPPVHLDITFGTGRIEGSTGIDDFTVGPFLVKGQSFGLVESEGGHNMHGNIFKTINFEGIVGLAFPEMSSTGTVPIYDNIISQGTLKENEFAFYMAKGSQVSALFFGGVDPRFYEAPIHMFPVTREHYWETSLDAIYIGDKKFCCEEGTKNYVILDSGTSFNTMPSGELGKLLDMIPSKECNLDDPEFTSDFPTITYVIGGVKFPLTPEQYLVRSKKNECKPAYMQIDVPSQFGHAYILGSVAFMRHYYTVFRRSDGTRPSLVGIARAVHNDDNSAYLSNVLNEYPGAHIRKEDLMMERSMSAPSMREL
What is the function of this protein?
Required for the processing-mediated maturation of a subset of microneme proteins, such as MIC6, and rhoptry proteins, such as ROP1 (PubMed:28898199).  By regulating microneme and rhoptry processing, plays an essential role in the lysis of the host cell membrane during egress and in rhoptry content discharge, which is required for invasion of host cells (PubMed:28898199).
What are the official names of this protein?
Aspartic protease 3, TgASP3, Toxomepsin 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: RECO_ORITI
Sequence: MNFRDKAIILKKRNIKENLAIVTVLTQSYGIYSGIIKDLHSKKNTIIYQIGNIVDFCWSARLDEHLGTINCELVKSYSYLIMSNKRNLLYTHSLIELTLMSFKERELHANLFEKWLENLESINTGNINVKNYINFELLILKEAGYRLNLDRCGVTNCTQNLIYVSPKSGQAISATVGEPYKHKLLLLPKFLVHNNCEPEDIYEIQAAFNLTAYFFNKYILIKKKLPITRELLLKSILEYSF
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ENO_CAMHC
Sequence: MIITDIYAQEVLDSRGNPTVRAFVALEDGTLAGATVPSGASTGKREALELRDGDERFCGKGVLKAVENVNTVIADEIVGMNVYEQKDIDNAMKKLDGTENYSNLGANAVLGVSMAVARAAAMSLGIPLYRYLGGANAQILPVPMFNIINGGAHANNSVDFQEFMVMPFGFDCFSDALRAVAEIYQNLKKILNELGYSTAVGDEGGFAPNLKDNEEPIKIIMQAIKKAGYEPGKQIKIALDVAASELYENGKYRLEGKTFTSEELIERYVKLCEKYPIFSIEDGLGEDDWEGWKKLTARLKDKIQLVGDDLFVTNEKILREGIEKGIANAILIKPNQIGSITQTMQTVRLAQRNGYRCIMSHRSGESEDSFIADFAVALNTGEIKTGATSRSERNAKYNRLLEIECENTEFLGNKI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARCA_LACLA
Sequence: MNNGINVNSEIGKLKSVLLHRPGAEVENITPDTMKQLLFDDIPYLKIAQKEHDFFAQTLRDNGAETVYIENLATEVFEKSSETKEEFLSHLLHEAGYRPGRTYDGLTEYLTSMSTKDMVEKIYAGVRKNELDIKRTALSDMAGSDAENYFYLNPLPNAYFTRDPQASMGVGMTINKMTFPARQPESLITEYVMANHPRFKDTPIWRDRNHTTRIEGGDELILNKTTVAIGVSERTSSKTIQNLAKELFANPLSTFDTVLAVEIPHNHAMMHLDTVFTMINHDQFTVFPGIMDGAGNINVFILRPGKDDEVEIEHLTDLKAALKKVLNLSELDLIECGAGDPIAAPREQWNDGSNTLAIAPGEIVTYDRNYVTVELLKEHGIKVHEILSSELGRGRGGARCMSQPLWREDL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXB_HUMAN
Sequence: MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLPLLVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHEPAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM
What is the function of this protein?
Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides (PubMed:11707436, PubMed:9694901, PubMed:8672428, PubMed:8123671).  The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide (PubMed:11707436).  Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A (PubMed:9694901, PubMed:8672428, PubMed:8123671).  During fertilization is responsible, at least in part, for the zona block to polyspermy.  Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida (By similarity).
What are the official names of this protein?
Beta-hexosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, Hexosaminidase subunit B, Cervical cancer proto-oncogene 7 protein, HCC-7, N-acetyl-beta-glucosaminidase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic vesicle, secretory vesicle, Cortical granule.
Protein: HBA_CHEKU
Sequence: SLSDKDKNTVRALWAKISKSADVIGAEALARMLTVYPQTKTYFTHWTDLSPSSTSVKNHGKNIMVGVSLAVSKMDDLTAGLLELSEKHAFQLRVDPANFKLLSHCLLVVISIMFPKEFGPEVHVSVDKFFANLALALSERYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GLGB_PROM1
Sequence: MTVSILLDSLKDDGQRLSECRHESPFSILGPQPFKDKWIIRIWMPEASEVELITQQTKIKLQNPNHEWIFEGVLEKDPGNDYQIKVNRGGIEHVQHDPWSFRKEWMGEIDRHLFAEGNHHHIWRKMGAHLTEINKKQGVMFCLWAPHAKSVSVIGDLNSWDGRHHPMQKRLGGIWELFIPGLSEGDLYKYEIRTEKGHCYEKADPYGFQHEVRPAKSSVISKIDSFQWNDQSWISNRDNRDPLEQPISVYEMHLGSWMHASSDDPFINSNGEHRAPVPAADMKPGSRLLTYKELANKVIPYVKERGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRFGSPDEFRAFVDSCHKEGIGIILDWVPGHFPKDQHGLAYFDGSHLYEHSDPRVGEHKEWGTLIFNYSRNEVRNFLVANLIFWFDQFHIDGIRVDAVASMLYKDYLRPEGEWIPNEDGGNENFEAVRFLQQANHVLFQHFPGALSIAEESTTWSGVTKPTDMDGLGFNLKWNMGWMHDMLDYFEIDPWFRQFNQNNITFSICYNFTENFMLALSHDEVVHGKSHLLHKMPGDDWQKYANTRALLAYMWTHPGKKTIFMGMEFGQRQEWNVWDDLQWDLLNYEPHKGIQKLVDDLNNLYKREPALWRNDFDEYGFQWIDCDDNKNSVISFMRREKTDGEWLVIVANFTPQNHSNYRIGVPVDGFYEEIFNTDASQYGGSNLGNMGGKSTDLYNIHGYENSIDLCLPPLSVLVLKHKSKKN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: NU3M_AILFU
Sequence: MNLIMTLFINITLTSLLVLIAFWLPQLNIYTEKTSPYECGFDPMGSARMPFSMKFFLVAITFLLFDLEIALLLPLPWATQTVNLTTMLTTALLLISLLAVSLAYEWTEKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL17_RHIWR
Sequence: MRHRVGGRKLQRTASHRTALFRNQSAALIKHEQILTTLAKAKELRPYVEKLITLAKKGGLANRRLAHARLQDDTQLKKLFEVLAERYASRNGGYTRIVKAGIRASDAASMAIIEFVDRDVSAKGQDSGPVETDEDVAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NRDR_MYCSJ
Sequence: MHCPFCRHPDSRVVDSRETDEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSREKVIKGVRRACQGRQVDDDALNLLAQQVEDAVRATGSPEVPSHEVGLAILGPLRDLDEVAYLRFASVYRSFESAADFEREIEALRAHQDVTRSG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PETD_MASLA
Sequence: MATLKKPDLSDPKLRAKLAKGMGHNYYGEPAWPNDLLYVFPVVIMGTFACIVALSVLDPAMVGEPADPFATPLEILPEWYLYPVFQILRSVPNKLLGVLLMASVPLGLILVPFIENVNKFQNPFRRPVATTIFLFGTLVTIWLGIGATFPLDKTLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide, Cytochrome b6-f complex subunit IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL3_ECOBW
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DJB11_PONAB
Sequence: MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY
What is the function of this protein?
As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins.  Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed.  May help recruiting HSPA5 and other chaperones to the substrate.  Stimulates HSPA5 ATPase activity.  It is necessary for maturation and correct trafficking of PKD1.
What are the official names of this protein?
DnaJ homolog subfamily B member 11, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, Endoplasmic reticulum DNA J domain-containing protein 3, ER-resident protein ERdj3, ERdj3, ERj3p.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: Y003_HAEIN
Sequence: MMYKAVFSDFNGTLLTSQHTISPRTVVVIKRLTANGIPFVPISARSPLGILPYWKQLETNNVLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKWVIYERSVTKIEIHPFDEVATRSPHKIQIIGEAEEIIEIEVLLKEKFPHLSICRSHANFLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHVGLGVAMGNAPNEIKQAANVVTATNNEDGLALILEEKFPE
What are the official names of this protein?
Putative phosphatase HI_0003.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: SYL_ECO5E
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPQWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA2_YEAST
Sequence: MSRKNSKKLKVYYLPVTLTQFQKDLSEILISLHAKSFKASIIGEPQADAVNKPSGLPAGPETHPYPTLSQRQLTYIFDSNIRAIANHPSLLVDHYMPRQLLRMEPTESSIAGSHKFQVLNQLINSICFRDREGSPNEVIKCAIIAHSIKELDLLEGLILGKKFRTKRLSGTSLYNEKHKFPNLPTVDSTINKDGTPNSVSSTSSNSNSTSYTGYSKDDYDYSVKRNLKKRKINTDDWLFLATTKHLKHDQYLLANYDIDMIISFDPMLEVELPALQVLRNNANKDIPIIKLLVQNSPDHYLLDSEIKNSSVKSSHLSNNGHVDDSQEYEEIKSSLLYFLQARNAPVNNCEIDYIKLVKCCLEGKDCNNILPVLDLITLDEASKDSSDSGFWQPQLTKLQYSSTELPLWDGPLDIKTYQTELMHRAVIRLRDIQDEYAKGTVPLYEKRLNETQRQNQLDEIKNSVGLTFKKKQEVEKSINDSEKRLKHAMTESTKLQNKINHLLKNRQELENFNKLPSNTISSENHLEEGSALADKLKEYIDKNATLFNKLKELQQANAEKSKLNDELRSKYQIESSKAAESAQTLKILQESMKSLENEVNGPLTKFSTESLKKELERLQNDFQSLKARNKFLKNYITLMNRQYDLKNKNNVQVEKAAANGTRFRSTRSNTPNYT
What is the function of this protein?
Required for activity of HDA1 histone deacetylase complex.  The HDA1 histone deacetylase complex is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
What are the official names of this protein?
HDA1 complex subunit 2, Histone deacetylase complex 1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the HDA2/3 family. HDA2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_RHIEC
Sequence: MSRRHKAEKREINPDPKFGDLVVTKFMNAIMLDGKKSVAENIVYGAFDAVQGKSKQEPLSVFHSALDNIAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIAAARKRNETTMIDRLSGELLDASNNRGSAVKKREDTHKMADANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.