PharMolix/UniProtQA huggingface dataset:
Protein: RIMM_HELAH
Sequence: MLLVGRIGKSVGLNGGLKLHLESDFPECLKKGVKVSVAPLNAFSHASFKDYVIHSYEHAKNLLFLETINTPEMARELTNLGLFMSETESKKLCVLKEGEFFYCDLIGLSVVEENEILGKVIEIQRISHIDYFMVETTLNLVEKGLAKIFLIPYRDFYIKEILLQDKKITTNNAKTLLENS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIP_MACCY
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIMALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: SAA2_PIG
Sequence: MKLFTGLIFCSLVLGVHSQWLSFLGEAYEGAKDMLRAYSDMREANFKNSDKYFHARGNYDAAQRGPGGAWAAKVISDARENVQRVTDWLKHGDSGHGVEDSRADQAANEWGRSGKDPNHFRPPGLPDKY
What is the function of this protein?
Major acute phase reactant.
What are the official names of this protein?
Serum amyloid A-2 protein.
What is the protein family that this protein belongs to?
Belongs to the SAA family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_STRZJ
Sequence: MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAAKIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVAAKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAYVMEEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTCN_MACNE
Sequence: MRALTLLALLALATLCITGQAGAKPSGAESSKGAAFVSKQEGSEVVKRPRRYLYQWLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGPV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium (By similarity).
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_CLOPS
Sequence: MSNVKRGGKFRRARKKVCIFCVDKAESIDYKDVAKLKKYITERGKILPRRISGTCAKHQRQLTDAIKRSRNIALLPFTTE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: BIOB_NEIMF
Sequence: MTVSPVALRRKTECKPHPTARYWKKCDVEALFGLPFLELVHQAAEVHRQNFNPREIQLSTLLSIKTGGCPEDCAYCPQSAHHNTNLGKEQMMDVDEIVEKAKIAKSRGASRFCMGAAWRGPKPKDVETVSAIIKAVKGLGMETCGTFGMLEEGMAEDLKEAGLDYYNHNLDTDPDRYNDIIHTRRHEDRMDTLGKVRNAGLKVCCGGIVGMNETRAERAGLIASLANLDPQPESVPINRLVKVEGTPLADAEDLDWTEFVRTIAVARITMPQSYVRLSAGRSNMPEAMQAMCFMAGANSIFYGDKLLTTGNPDEDGDRILMEKLNLYPLQFELEGEVAEVEKASGIKVDY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RRF_STRP1
Sequence: MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEKELLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYRM7_DANRE
Sequence: MGTRLKVLRVFKDLHRTRRDVFRDDNRALTAARVKINEEFKKNKNETSDDNIKEMLKMARAVETILRESVIQAEHVDENKIVLRPRKSLLLENVPYCDAPSKKT
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Complex III assembly factor LYRM7, LYR motif-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNPA_SHISS
Sequence: MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: EFTS_SODGM
Sequence: MADITAALVKELRERTGAGMMECKKALVEAQGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILTKIAQDGKYGVIIELNCETDFVAKDGGFKAFGDEVITAALNERITDVEALKAKFEEQRTALVAKISENINIRRLGVLEGGVLGSYLHGARIGVMVSAAGADEELVKHVAMHIAASKPEYVNADDVPADVVAREHQIQLDIAMQSGKPREIAEKMVEGRMRKFTGEISLTGQHFVMDPSKTVGQLLGEHGAKINNFIRFEVGEGIEKAEVDFAAEVAAMGKQF
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPA5_MYCBO
Sequence: MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDGTAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVDELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQAVPVTRLWLSKQQTSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYGWIME
What is the function of this protein?
Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenolphthiocerol dimycocerosate esters (PDIM) synthesis.  Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols.
What are the official names of this protein?
Phthiocerol/phthiodiolone dimycocerosyl transferase, Acyltransferase PapA5, Phthiocerol/phthiodiolone O-acyltransferase, Polyketide synthase-associated protein A5.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase PapA5 family.
Protein: NUON1_AQUAE
Sequence: MNWNAILPEAILAIGILTVFILELFLERKHYKFLSVLAFIFVVLSGYSIFFVNYPAKLFFDGFSVDALNLIGKLFILAVTGFVLLSSYDYFSKKNSQYGELPYLYLIATLGLMVMISSDNLAIIFTGLELASITMYILVGLFRREYLSKEGAFKYLVIGTTGTSMYALGSALVYASSGSMVLSPVKEENTLFALGVILIISALALKVSAVPFHFWTPDAYEGAPTPTTAYLSTVPKIGMYFLFVKLTMYLFSAFPDWKYVVMLLAVLSMFYGNIVAYAQKSVKRLLAYSSIAHAGYFLTALTAVDKHLFSALLFYVFVYALATVGAFTVLAILEKKEGWTHHFLDFKGLKEENPVLASMLALFLFALIGIPPAAVFLGKLGIFFGLVKTDMFALGILFAIASLISAGYYLKVIVYMFLYSGEVRHGQTTVSAGEAFTVLGTAFLVIFFGLFPHVVLDFILRALS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_MYCMM
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRFGGQVVKAGEILVRQRGTKFHPGVNVGRGGDDTLFAKAAGAVQFGIKRGRKTINIVEPATQDA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PURQ_RHORT
Sequence: MNSAIIVFPGTNRERDMAKALTLVGGKAPQMVWHRDSALPAGLDLVVLPGGFSYGDYLRSGAMGARSPILDAVRRFAEAGGHVLGVCNGFQILTEAGLLPGALMRNRDLRFICRDVHLRVETIASPYTSAYGLGEVARVPVAHHDGNYFADDATLAQLADEDRVAFRYCAADGTVGEASTPNGSRDAIAGILSANRRVLGMMPHPENLVEPALGGIGGRALFQSIVESLS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3668_CROS5
Sequence: MILTIDNILTSEELTELTDILSQGNFVDGQTTAGWHAKLVKQNSQLDKTAPEVKSLEALVINALQRNLLFKLAIHPKHIHSLRFSRYEPKMHYGSHTDNALMGGQQFFRSDVSFTLFLSSPESYEGGELIIEKPEGDLSYKLNPGSIVLYPSTFLHRVETVKTGTRLVVVGWVHSLIRDTAQREILFDIDTVRRSIFAKDGKSVEFDLLAKTHANLLRQWAD
What are the official names of this protein?
PKHD-type hydroxylase cce_3668.
Protein: YQIB_ECOLI
Sequence: MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQYRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARYDYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY
What are the official names of this protein?
Uncharacterized protein YqiB.
Protein: PSB_METMP
Sequence: MISNSEYHKEYMKGTTTVGLLCNDGVVLATDKRATMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQSLIRLISAEAKIYKMRTGNNMTPLSCTTLISNVLHGNRHYPLLTQLILGGYDLINGAKLFSLDPVGGINEESSFTATGSGSPTAYGVLESEYKSDIAIEKGLLIAVKALSSAMQRDAYSGNGISLAHINKDGVKLYSDAEIEGFLKKINRKR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCC2_ARATH
Sequence: MSNPSSSGLGSSSGLTHFGIGLANTVQSEVTPYLPLPSLPIFCGAAEPGEFKLFDEVGQGSGYRSLDRSEILAQSSRIANMLHETDVSYLDLRNEARAPDCNSGEHFQLYDLVLRCNPGAFEYVTPGPTCDPLFTNEGPQKIISEPSVPVKMQRQTDTHLARSIEPEPVKRVLRPNHVEDHSWQHETLTNQSPKDVTAYDSRPETITMNELSASKKPKGKKKRKDDLSSVQPDPSVLQESIVQNFCEMLEDFCGRAEVPGDDRDEAEWSSVPVDEVRVLINELMTIRSKMLLHMVPVDILSRLLRTLDHQIHRAEGLSIYSEHSDSDSVLLVLGALESIHASLAVMANSDMPKQLYKEEIIERILEFSRHQMMAVMSAYDPSYRTGSKPAENLAFEGDDDDDNPDHDMGSASKRRRIVKNSKVKKASVNRISGAVNTALQKLCTILGLLKDLLLVERLSDSCILQLLKTSITTFLVENIQILQLKAISLIGGIYNSYSQHRTYVIDEISQLLWKLPSSKRALRAYLLPDEEQRQIQMVTALLIQLVHNSTSLPETSRQAASGNSILETSVDVGYLTKCHEAATETCCLFWTRVLERFTSFKGQDASEIKLIIENLVMDLLTALNLPEYPSVSPILEVLCVILLHNAGLKSKDVSARIMAIELLGTIAARLKRDAVLCSKDRFWTLLESDSEISVDQVCTKDCTFCLGKRAGNLLVCQICQRRFHGDCLGLKELDISSRNWHCPLCVCKRQLLVLQSYCKTDTKGTGKLESEESIENPSMITKTEVVQQMLLNYLQDVGSADDVHTFICWFYLCLWYKDVPKSQNKFKYYIARLKAKSIIRNSGATTSFLTRDAIKQITLALGMNSSFSRGFDKILNMLLASLRENAPNIRAKALRAVSIIVEADPEVLCDKRVQLAVEGRFCDSAISVREAALELVGRHIASHPDVGIKYFEKVAERIKDTGVSVRKRAIKIIRDMCTSNPNFSEFTSACAEILSRISDDESSVQDLVCKTFYEFWFEEPPGHHTQFASDASSIPLELEKKTKQMVGLLSRTPNQQLLVTIIKRALALDFFPQAAKAAGINPVALASVRRRCELMCKCLLEKILQVEEMSREEGEVQVLPYVLVLHAFCLVDPGLCTPASDPTKFVITLQPYLKSQADSRTGAQLLESIIFIIDSVLPLIRKLPLSVTEDLEQDLKHMIVRHSFLTVVHACVRCLCSVSKLAGKGVSIVEHLLQFFFKRLEAQGSDNTQIAGRSLFCLGLLIRHGNSLISTSGGKNFNLSGCLNLFKRHLRTEDIALKVRSLQALGFILIARPEYMLEEDIGKIIETTLADEANGRMKMQALQNMYEYLLDAEKQLGSEKASDNTVNSVEQGGHNVPVAAGAGDTNICGGIVQLFWDKILGRCLDFDDQIRQTSLKIVEVVLRQGLVHPITCVPYLIALETDPQEANQKLAHHLLMNMHEKYPAFFESRLGDGLQMSFIFMQSISQVTSEPNQSLQQKGSTNMLGKNDHASSTLTQARLGVSRIYKLIRGNRVSRNKFMTSIVRKFDNPTWNGSVISFLKYCTETLALLPFTSPDEPLYLVYSINRVMQIRAGAVESNLKALLHKDSAKTQHGNGAYQQDPIPGHMNMMDLNTRIQEEPRHWNSYGHATLIDLNGSVYQDSRDQFTSYQVHNGKADVHKMTSSDPPELSTDDLQKIQVDCLAAIAIQLLLKLKRYLKVTYSLNDDRCQAYSPTEPLKPGDPLSRQSVAFDLSETRTDLPSTYQDLVQRYQEFKNAMREDTVDFTIYSTNVKRKRPTPRKTSRSAKKTVAYNEDDDDDDNDDRGWHGGGGRGAARRLNYSTRSSNRR
What is the function of this protein?
Essential protein required for cell fate determination during embryogenesis (PubMed:19228337, PubMed:15266054, PubMed:28137757).  Involved in sister chromatid cohesion during meiosis and mitosis (PubMed:19228337, PubMed:19533160).  Forms a complex with SCC4, which is required for the association of the cohesin complex with chromosomes (PubMed:28137757).  Plays a structural role in chromatin, especially in centromere organization, chromosomal axis formation, and distribution of the cohesin subunit SCC3 on chromosomes (PubMed:19228337).
What are the official names of this protein?
Sister chromatid cohesion protein SCC2, Protein EMBRYO DEFECTIVE 2773, Protein SISTER-CHROMATID COHESION 2, AtSCC2.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with chromatin.
Protein: HTPG_RICBR
Sequence: MKQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSEAELVAGDSNFKITVKGDKNNGQVIIRDNGIGMNKEDLIENLGTIARSGTANFLKNLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDKVYVWESEGEGEYIVSSSDREFSRGTEIALHIKKEEDSFLDHFRLKHIVKSYSDHIAVPIYFFDEGDNNEIQLNSASALWTRSKSEITEEQYKEFYKSLSYAVDDPWVTMHNKNEGAIEFTNLLFIPSSKTYDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNNVLEKIKNAITKRVLGELKKKKEDSPDEYNNFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHNKMISLDEYIKGFKEGQNTIYYLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHTIKSATRSDIDVDQATSSSEEKNKDDKKSDDEYKSLTDYFKEVLGILVKDVKISKKLTSSPACLAVSEAAMDIRMERFLIEQKQIANASAKNLELNPKNKIIEKIFNDLKANNKNNEELVKLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CG121_CRYNJ
Sequence: METYAYPAFPPEYSNIHIALFKNVTNAPQIRKRLIEASQMTGPEGDKAREEVDFGFVEANLLVSKEHLLIAILSTLLYAFPSTGPAPTDPPPLSDIADPDVSSLSLSSSSETRQPKTRSHNLHSELLLLLSPNNNITDSIRRHGVSDITTNLAVVKFGKRGDRVEEVYEAMKNVVEGELIGWEGISEGTDWARVDKIYKLNELNALKTADMVEKKRTAVISTVAIKNVI
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.  CGI121 is not required for tRNA modification (By similarity).
What are the official names of this protein?
EKC/KEOPS complex subunit CGI121.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: PPK5A_BLADU
Sequence: AGESSNEAKGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5a, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KPTA_THEON
Sequence: MFPGRRKVSKLMAYILRHSPEEFGLRPDVEGFVPLSELVEALKTIYPDVTEEFVREIVARDAKGRYEIQGDRIRARYGHSFPVSLDHEEDTESRFLYHGTPRRNLESILREGLKPMRRQFVHLSTSKSEAIKTGRRHGRDVVLLVIDAECLRKKGLKVYKAGKNVRIVEKVPPECITLEV
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: PCKA_PORGI
Sequence: MSKLDLTKYGILNATEIIHNPSYEFLFEEETKAGLEGFEKGQLTELGAVNVMTGVYTGRSPKDKFFVMDDTTKNTIWWTSDEYKNDNKPVTPEAWKSIKKLAVEQLSGKRLFVVDTFCGANESSRLKIRFIMEVAWQAHFVKNMFIRPTEEELANYGEPDFVVMTASKAKVENYKELGLNSETAVVFNLTEKVQVILNTWYGGEMKKGMFSYMNYLLPLRGMASMHCSANTSMDEKETAIFFGLSGTGKTTLSTDPKRKLIGDDEHGWDKDGIFNFEGGCYAKVINLSRENEPDIYNAIRRNALLENVTVDAAGKIDFGDKSVTENTRVSYPIYHIENIVKPVSKAGHAKKVIFLSADAFGVLPPVSILTPEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTKYAEELVKKMEMVGATAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIDKAPTKAIPFFDFKVPTALPGVDPNILDPRDTYADAAEWTTKAKDLAERFIKNFVKFTGNDAGKALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC26_DANRE
Sequence: MLRRKPTRLELKLDDTEEFESVKKELESRKKQRDEVDVVGVATSSEMSGAAGGTADGKTREQMIHERIGYKPHPKPNTLPSLFGNLQF
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).  May recruit the E2 ubiquitin-conjugating enzymes to the complex.
What are the official names of this protein?
Anaphase-promoting complex subunit CDC26, Cell division cycle protein 26 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIS1_DROME
Sequence: MKMVLSQRQREELNQAIADYLGSNGYADSLETFRKEADLSTEVEKKFGGLLEKKWTSVIRLQKKVMELEAKLTEAEKEVIEGAPTKNKRTPGEWIPRPPEKFSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as nuclear migration during cell division, mitotic spindle formation and the removal of mitotic checkpoint proteins from kinetochores at the metaphase to anaphase transition.  Required for several aspects of neurogenesis including neuroblast proliferation, neuronal cell differentiation, dendritic growth, branching and maturation and axonal transport.  Required for synchronized cell divisions in the germline, fusome integrity and oocyte differentiation.  Acts together with BicD, Egl, dynein and microtubules to determine oocyte identity during oogenesis.  Also required for nurse cell to oocyte transport during oocyte growth and for the positioning of the nucleus in the oocyte.
What are the official names of this protein?
Lissencephaly-1 homolog, DLis-1, Dlis1, Lissencephaly1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome, centromere, kinetochore. Note=Localizes to the plus end of microtubules. Also localizes to the mitotic spindle poles from late prophase through to telophase and to kinetochore microtubules in metaphase. Localization to kinetochore microtubules is reduced in anaphase and telophase. In oocytes, it concentrates in the cortex from stage 5 of oogenesis.