PharMolix/UniProtQA huggingface dataset:
Protein: AROA_LEUCK
Sequence: MIRLTPASAHGLHGHVTVPGDKSISHRALMFGAIAKGQTVITNFLASDDVLHTMTVFRNLGVAIQQNENSVRIQGQGFDGLTPPKKPLDMGNSGTSTRLLMGLLSKQNFDMSIIGDESLSQRPMTRVMKPLTEMGAKIDLTANGTLPGIIQANATLRGITYDMPVASAQVKSAILLAGIQAEGETCVIEKIASRDHTERMLRQFGGQLESKNGVITLKKQQQLQGQHVDVPADISSAAFFLVAALITPNSELTINRVGINPTRDGILKILTRMGASIEVTPIDTQGEPLADLTVRTQTLHGIDITAADIPSAVDELPIIALAATQADGDTIISGAEELRVKETDRIATVISELSKLGANIEEKPDGMIIHGGQSLTADNDAVLLDSCGDHRIAMMNAIAALITTGDVILTGEDAMSVSYPGFLEDLSEVML
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_MANSM
Sequence: MEQKQNSQKTIVVKFGTSTLTQGTPKLNRAHMIEIVRQLAQLHQEGYRLVIVTSGAMAAGRHYLNHPKLPPTIASKQLLAAVGQSQLIQTWEQLFAIYDIHIGQLLLTRADIEDRERFLNARDTLHALLDNRIIPVVNENDAVATAEIKVGDNDNLSALVAILVQAEQLYLLTDQQGLFDSDPRKNPQAKLIPVVNEITDHIRSIAGGSGTTLGTGGMSTKITAADIATRSGIETIIAPGNRENVIADLAHGEAIGTKFTVQTDKLESRKQWLFAAPSAGILTIDQGAENAILEQHKSLLPAGIVNIEGRFSRGEVVKIRTQQGKDIALGMPRYNSDALYLIQGKKSQNIEKILGYEYGSVAIHRDDMIVLNK
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_SALTY
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTLVAEAVKATLPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAEALLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: SGRM_PEA
Sequence: MDTLTSAPLLTSKFKPSFSPQQKPCFPHRRRFENGKKKQSIVPVARLFGPAIFEASKLKVLFLGIDENKHPGNLPRTYTLTHSDVTSKLTLAISQTINNSQLQGWYNRLQRDEVVAQWKKVKGKMSLHVHCHISGGHFLLDIFARLRYFIFCKELPVVLKAFVHGDGNLFNNYPELEESLVWVFFHSKILIREFNKVECWGPLKEASQPTSGTHSDLKLPQSCEEDCECCFPPLNLSPIPCSNEVINNTYEPIDGIGTQHGNL
What is the function of this protein?
Non-functional protein probably interfering with the disassembling mechanism of the intact light-harvesting complex of photosystem II (LHCII) in the thylakoid membranes.  Responsible for a stay-green phenotype.
What are the official names of this protein?
Non-functional protein STAY-GREEN, chloroplastic, Protein STAYGREEN.
What is the protein family that this protein belongs to?
Belongs to the staygreen family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TYSY_MYCLE
Sequence: MLIATPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFPLVTTKKVHFKSVVYELLWFLRGDSNVAWLHEHGVNIWDEWASSTGDLGPIYGVQWRSWPTSSGDYIDQISTALDLLRTEPDSRRIIVSAWNVGEIPQMALPPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFNIASYALLTHMMAAQSGLLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDSIFDYVYEDVVVTNYDPHPAIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCHP_DANRE
Sequence: MALPTLSAHWPSRVRTLEQQLVRQREQEARLRRQWEQHSQYFREQDVRSSKQAQWSSRQSFHRSMSAFQRDRMREEKQRKLEERRERLRTMLQEERDQLEAELRNIHPDRDTLARQLVEKTDALRSAREERRKNLAQELLREHWKQNNSQLRKVESELHKDHIVSQWQVQQQEKKQADERTQEEKQRFENEYERTRQEALERMRKEEENRKWEEKKRAEELLKQMEELKLREQEAERLKQEQETLMSKRWELEKLEDERKMMEESRRKTEFGRFLTRQYRAQLKRRAQQVQEELEADRKILAALLEGELDEQRFHKARRERAVADAAWMKRVIEEQLQLEREREAEFDILYREEAQRVWEKREAEWEKERRARERLMREVLAGRQQQLQERMQENRLAREESLQRREELLQQLEQDRLTLRLEKEQQEGLRTARIQEIDNQVEQRRKEQWEQQQTLEQEEAQEREELRLQEEELRLETDRMIRQGFQERIHSRPRSAWT
What is the function of this protein?
May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery.  May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity).
What are the official names of this protein?
Trichoplein keratin filament-binding protein, Protein TCHP.
What is the protein family that this protein belongs to?
Belongs to the TCHP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: IWS1_KLULA
Sequence: MSDTERSLSADKKSDTELETPALSNVDPQERTRKHIEATAESDSDADLDPALGNGLPAHDDDEETGSRPVLDEATRKRQDLEARMDQILHKPKKKRTRRDEDDLEQMQDERILRLKDEMNIAAQKDIDTLNERLETGDTKLVAMEKVKLLPKVVKVLSKVNLADTILDNNLLQSVRIWLEPLPDGSLPAFEIQKSLFAALDNLPIKTEHLKESGLGRVVIFYSKSKRVEQKLARLADKLVAEWTRPIIGASDNYRDKRVLKLEFDVEKHRKKTILDTAKSKKKRSKRMEVDEEKYKSSYEQAAARRNRAAAPAQTTTDYKYAPISNIDAVNRNAGVGTSVDSSELYKRLNSKLSGNKHKRSK
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_PSEP1
Sequence: MSVPTVLERIIARKFQEVAERSARVSLAELEGLAKAADAPRGFANALIEQAKRKQPAVIAEIKKASPSKGVIREHFVPAEIAVSYEKGGATCLSVLTDVDYFQGADEYLQQARAAVSLPVIRKDFMVDPYQIVEARALGADCVLLIVSALDDVKMAELAATAKDVGLDVLVEVHDGDELERALKTLDTPLVGVNNRNLHTFEVSLETTLDLLPRIPRDRLAITESGILNRADVELMAINEVYSFLVGEAFMRAEQPGLELQRLFFPEQVKKTVQQLD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: FRDC_PASMU
Sequence: MTATTSKRKKYVREMKPTWWKKLDFYKLYIAREATAIPTLWFCLVLLYGVISLGSLDSFGNFISFLKNPIVIILNIITLGAMLLNTVTYYVMTPKVLNIIVKNERINPNIITMALWAVTAFISLVILVFMYV
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK1_AQUAE
Sequence: MDIIKAYIILSIALFLIGLLGVIVRKNLITVLVSTELMLNGINLALVAADKVLGRVDGQIFAFFVLTVAAAEVAVGLGLIVAIFRLKGYEASHEISQLRD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBP_PSEAE
Sequence: MRDLILGGARSGKSRLAERLAAESGLAVSYIATAQAGDGEMGRRIAEHRARRPAHWRTLEEPLALAATLRSEAEAGRCLLVDCLTLWLTNLLLCDDPQRLDGEREALLECLGELPGRIILVSNETGLGVVPLGELSRRYVDEAGWLHQAIAERCERVTFTVAGLPMPLKGEPL
What is the function of this protein?
Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
What are the official names of this protein?
Bifunctional adenosylcobalamin biosynthesis protein CobP, Adenosylcobinamide kinase, Adenosylcobinamide-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobU/CobP family.
Protein: HCST_MACFA
Sequence: MIHPGHILFLLLLPVAAAQTTPGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCARPRRSPAQDGKVYINMPGRG
What is the function of this protein?
Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation.  Functions as docking site for PI3-kinase PIK3R1 and GRB2.  Interaction of ULBPs with KLRK1-HCST triggers calcium mobilization and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways.  Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells.  In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors.  In T-cells, it provides primarily costimulation for TCR-induced signals.  KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells (By similarity).
What are the official names of this protein?
Hematopoietic cell signal transducer, DNAX-activation protein 10, Membrane protein DAP10.
What is the protein family that this protein belongs to?
Belongs to the DAP10 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AXIN1_RAT
Sequence: MNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTSIKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIKDCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGMSGYLPTLNEDEEWKCDQDADEDDGRDSVPPSRLTQKLLLETAAPRAPSSRRYNEGRELRYGSWREPVNPYYVNSGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRMPKEIRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGEMPSGPMASHKLPSVPAWHHFPPRYVDMGCSGLRDAHEENPESILDEHVQRVMRTPGCQSPGPGHRSPDSGHVAKTAVLGGTASGHGKHAPKLGLKLDSAGLHHHRHVHHHVHHNSARPKEQMEAEAARRVQSSFSWGPETHGHAKPRSYSESTGTNPSAGDLAFGGKASAPSKRNTKKAESGKNASAEVPSTTEDAEKNQKIMQWIIEGEKEISRHRKAGHGSSGMRKQQAHESSRPLSIERPGAVHPWVSAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEARRRLEEEEKRANKLPSKQRTKSQRKAGGGSAPPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAILPVFEEKIIGKVEKVD
What is the function of this protein?
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (By similarity).  Controls dorsoventral patterning via two opposing effects; down-regulates beta-catenin to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway (By similarity).  Also facilitates the phosphorylation of APC by GSK3B (By similarity).  Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation (By similarity).  Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7 (By similarity).
What are the official names of this protein?
Axin-1, Axis inhibition protein 1, rAxin.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Membrane. Note=On UV irradiation, translocates to the nucleus and colocalizes with DAAX (By similarity). MACF1 is required for its translocation to cell membrane (By similarity).
Protein: SPAT6_MOUSE
Sequence: MPKVKALQCALALEIRSVTCPGVVLKDKEDIYLSICVFGQYKKTQCVPATFPLVFNARMVFEKVFPEAVDPGDVVAQLEYDTAVFELIQLVPPVGETLSTYDENTRDFMFPGPNQMSGHHDSNRQVTMRRISGLRGIAPKLEFSTTSVITECLISSRKCRTQDKFTYHSAPVEKSHGRLQCRTSRSQKKKSKSPERSKYCINTKNYEQPTISSKSHSPSPYTKRRMCELSEDTRRRLAHLNLGPYEFKKETDKPPFVIRHVDPPSPRTDNFFGSPGRDCERDGWVRMHSDHPHIGCCRSKDYKVIRSPHGRDFEDPFERCEEYLSPRTCSKPQHSARTLLVHSAPSTTPKHCASPVLNRASLRERFHSDWCSPPNCDEIHDRVKDVLKSHQAHARHLCDERDPEREDELELKRSLLYRDSAYDSDPEYSSFQRPRGSFHLDDGECWSNRAASCKGKSHRPVFENSMDKMYRNLYKKACSSVSHTQESF
What is the function of this protein?
Required for formation of the sperm connecting piece during spermiogenesis.  Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis (PubMed:12771232, PubMed:25605924).  May be involved in myosin-based microfilament transport through interaction with myosin subunits (PubMed:25605924).
What are the official names of this protein?
Spermatogenesis-associated protein 6, Kinesin-related protein.
What is the protein family that this protein belongs to?
Belongs to the SPATA6 family.
What are the subcellular locations of this protein?
Secreted. Cell projection, cilium, flagellum. Note=Specifically localizes to the segmented columns and the capitulum of the sperm connecting piece.
Protein: SYN_LACH4
Sequence: MTELISIKDSSKHVDQEVKMHVWLTDKRSSGKIIFLQLRDGTAFFQGVVRKNDVTDEVFEVAKSLRQESSFYITGTVHEDARSHFGYEIQITDLKVVSNNEGYPIGNKEHGIDFLLDHRHLWLRSKKPFAIMQIRNTMFKATVDFFEKEDFIKFDAPIFMHSAPEGTTQLFHVDYFDHDAYLSQSGQLYGEAGAMAFGKIFTFGPTFRAEESKGRRHMTEFWMMEPEMAWMHQDESLDLQERYLAYMVKQVLDKNEYELKILGRDPEKLRPTTEGNFVRLPYDDAVKMLQDAGRDFKWGDDFGAPDEGYISEQYDRPVFIVNYPTSIKPFYMKKNPDNPKEYLCADVIAPEGYGEIFGGSEREGNYEVLEQQIIDAGLNLEDYQWYLDLRKFGGVPHSGFGMGFERTIAWVCHLDHIREAIPFPRLINRMQP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHRD1_BOVIN
Sequence: MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDSDEIKIGTSCKNGGCSKTYQGPQSLEEVCVYHSGVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKTEEKQKEETTE
What is the function of this protein?
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2.  Proposed to act as co-chaperone for HSP90.  May play a role in the regulation of NOD1 via a HSP90 chaperone complex.  In vitro, has intrinsic chaperone activity.  This function may be achieved by inhibiting association of ROCK2 with NPM1.  Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (By similarity).  Involved in stress response.  Prevents tumorigenesis (By similarity).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, CHP-1, Protein morgana.
Protein: ASPG2_HAEIN
Sequence: MKLTKLALCTLFGLGVSIANAADLPNITILATGGTIAGSGQSSVNSAYKAGQLSIDTLIEAVPEMKNIANIKGEQIVKIGSQDMNDEVWLKLAKAINAQCKSTDGFVITHGTDTMEETAYFLDLTVKCEKPVVLVGAMRPATEKSADGPLNLYNAVVVAADKKSSGRGVLVAMNNEVLGARDVTKTSTTAVQTFHSPNYGSLGYIHNSKVDYERSPESKHTINTPFNVEKLDSLPKVGIIYAYSNAPVEPLNALLNAGYQGIVSAGVGNGNVNAAHLDRLEKAAKDSVVVVRSSRVPTGYTTRDAEVDDSKYGFVASGTLNPQKARVLLQLALTQTKDPKVIQQYFEDF
What are the official names of this protein?
Probable L-asparaginase periplasmic, L-ASNase, L-asparagine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DDL_TROWT
Sequence: MRRLLLLFGGRSQEHSVSYASARALLEHICDEWTVIPVGITKHGDFVYCSTVSEQDYGEVIDNGNRVVWPSRAGCKKIEVVQARGKSFFVEFDLVFPLLHGVFGEDGTIQGMLDLLDIPYVGSGVFASAAAMDKHYTKILCSHAGIPVLPWYLIKGHAWHKNRDSFLKQISDRFTFPLFVKPVDAGSSFGCTFVDFFEQLPVAIEHALQHGKSAIVEPALDAPEVFCSLIENNGVLQCSELVFVKHSGSKFYDYSAKYLNPVEFVIPAQFDNTDGYAEIASKVFFELGCRHYARIDFFVTESGLVLNEINTSPGLTQKSIFPSSFKSMQYSQVIETILASAYCQVKR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KXD1_YEASL
Sequence: MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit KXD1, BLOC-1 subunit KXD1, KxDL homolog.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: PPK1_MYCTO
Sequence: MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQESLMERHRSP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: DPDP_THEFY
Sequence: MSPKTVFSTDTHREPIPPQPHPSGARPPQLPRELIPRHVAIVMDGNGRWAKQRGLPRTEGHKAGESSLFDVIEGALELGVPYLSAYAFSTENWKRSPDEVRFLMGFNRDVIRRRRDELHARGVRVRWAGRPGRLWKSVIKELTEAEELTKHNTKLTLQFCVNYGGRAEIADAAAALARDVAAGRLSPNRVTEATLARYLYHPDIPDVDLFIRSSGEQRLSNFLLWQSSYAEFVFLDTLWPDFDRRHFWQACEIYARRDRRYGGAEPNPVGPPQSAAGAQGQD
What is the function of this protein?
Catalyzes the synthesis of Z,E-mixed prenyl diphosphates by a condensation of isopentenyl diphosphate to an allylic diphosphate.  It shows a large substrate specificity accepting dimethylallyl diphosphate (DMAPP), GPP, E,Efarnesyl diphosphate (FPP), E,E,E-geranylgeranyl diphosphate (GGPP), neryl diphosphate (Z-GPP), and (2Z,6E)-farnesyl diphosphate (Z,E-FPP) as allylic substrates.  The enzyme exhibits the highest activity when Z,E-FPP is employed as an allylic substrate.  The major product is dodecaprenyl diphosphate (C60) under every allylic substrate conditions, but the enzyme is also able to synthesize even C70 prenyl diphosphate as the maximum chain-length product.
What are the official names of this protein?
Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific), Cis-prenyltransferase, Dodecaprenyl diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CU94_CONCL
Sequence: MNCYLILTVALLLTSAMTGTTTAGQLNKKGVTLREDDRFPCNPGGCACRPLDSYSYTCQSPSSSTANCEGNECVSEADW
What are the official names of this protein?
Conotoxin Cl9.4.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_ECOLI
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: DCD_BORBR
Sequence: MSIKSDRWIRRAAEAGMIEPFEPGQVRTAGGNRIVSYGTSSYGYDVRCADEFKIFTNINSTIVDPKQFDEKSFVDFKGDVCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYAGEGCAQMLFLESDEVCETSYRDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: DEOD_HAEI8
Sequence: MTPHINAPEGAFADVVLMPGDPLRAKYIAETFLQDVVEVTNVRNMLGFTGTYKGRKISIMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGTVRMDVKVRDVIIGLGACTDSKVNRIRFKDNDFAAIADFDMAQAAVQAAKAKGKVVRVGNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYGVAAEYGAKALTICTVSDHIRTHEQTTAEERQLTFNDMIEIALDSVLIGDAL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: CHBG_SALCH
Sequence: MERVLIVNADDFGLSKGQNYGIVEAYRNGVVTSTTALVNGEAIDHAAQLSRELPALGVGMHFVLTLGKPVSEMPGLTRDGLLGKWIWQMAEEDTLPLDEIAHELACQYQRFIDVFGREPTHLDSHHHVHMFPQIFPIVARFAAQRGIALRIDRQTVLNADDLPSDLRSTQGFSSEFYGEEITEACFLRILDASTHRGEASLEVMCHPAFVDNIIRQSAYCYPRLTELEVLTSASLKAAIAERGYRPGSFLDI
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.