PharMolix/UniProtQA huggingface dataset:
Protein: SYA_SALTO
Sequence: MKTAEIRRRYLAHFEANGHAVVPSAPLPAISDPNLLFVAAGMMQFVPYFLGQQTAPYKRAVSVQKCLRTPDIDEVGKTSRHGTFFQMNGNFSFGDYFKDEAIPLAWELSTKPVDAGGLGLDPDRIWPTVYLDDDEAFQIWRSVGVPADRIVRRGKADNFWSMGIPGPCGPCSELFYDRGPEYGREGGPEVDEDRYLEFWNLVFMQFERGPGTGKEDYPILGDLPAKNIDTGMGLERMASILQGVDNLYEIDEVRPILAKAAELTGKRYGAHSGQVASESHPDDVRLRVVADHVRTALMLIGDGVIPSNEGRGYVLRRIMRRAIRSIRLLGWQERAMPELLPVARDCMSASYPELATDFGRIADYAYAEEDAFLSTLRAGTTILDTAIAETRTAGRRAISGAKAFQLHDTYGFPIDLTLEIASEQGLQVDAEGFRRLMADQRARAKADAQARKTGHVDLSAYRTVLDEGGPVTFTGYQEVSRESTVRAVLGAASPHAAAVEGETVELVLDTTPFYAEGGGQQPDLGVITVGGGQVEVLDVQQPVPGLIVHRARVLRGEVRVGETGFAEIDTDRRRAISRSHTATHLVHQTMRNFLGESATQAGSLNAPGRLRFDFNTPTGVAPSVLRDVEQQVNEALLADLEVRAFVTSLAEARRIGAMALFGEKYGEQVRVVEVGDYARELCGGTHVGRSGQLGLVKILSESSIGSGVRRVEALVGIDAFNFLAREHLLVARLAELYRVPSDQVAERVEQTVTQLRDAEKELEKLRAQLVLGGAAALAAQASEVRGVAYVGTEAPEGAAGNDVRTLAQEIRSRIDPARPAVVAVAARANGKASLVVAVNPAARSQGLSAADLVKVAFAGRGGGSPELAQGGGLPAAEAPGLLRTVENAIAGA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAU1_AILME
Sequence: MSQVQVQVQNPSAALSGSQILSKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSASLTPTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRTLQSEPLPERPEGRRPGEQVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKSFVTRVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPTFERVKPRIKKKTKSIVRLQGSTDCSQGMNPISRLAQIQQAKKEKEPEYLLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRLPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRVAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQPSTEMPRTGNGPMSV
What is the function of this protein?
Binds double-stranded RNA (regardless of the sequence) and tubulin.  May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site (By similarity).
What are the official names of this protein?
Double-stranded RNA-binding protein Staufen homolog 1.
What are the subcellular locations of this protein?
Cytoplasm. Rough endoplasmic reticulum. Note=Localizes exclusively with the rough reticulum endoplasmic (RER).
Protein: PRL_ANGAN
Sequence: MAQRFKGRSLFLTALLCLASQGYAVGLGDMLERASQLSDKLHSLSTSLTNDLDTHFPPMGKILMPRPSMCHTASLQTPHDKDQALRVPESELLSIARALLLSWNDPLLLLASEAPTLSHPQNGAIYSKTRELQDQSNSLSSGLDRLIHKIGSSSKALSPLPLQGGDLGSDKNSRLINFYFLLSCFRRDSHKIDNFLKLLRCRAAKQDRC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEPA_SALAR
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDFKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVTDVLERLVRDIPPPQGDPDGPLQALIIDSWFDNYLGVVSLVRIKNGTMRKGDKIKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDILGAPVGDTLTSARNPAEKALPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPENSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTAKEIIYVDSPSKLPPLNNIYELREPIAECHMLLPQAYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINNERVDALALITHRDNAQNRGRELVDKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYW_BORBR
Sequence: MNTRVLTGITTTGTPHLGNYAGAIRPAIQASTQPGVDAFFFLADYHALIKCDDPARVARSRLELAATWLAAGLDPERVTFYRQSDIPEITELCWLLTCVTPKGLMNRAHAYKASVDQNAAKGVEPDDGVTMGLFSYPVLMAADILLFNANQVPVGRDQVQHLEMARDIAQRFNHLYGREFFVLPEVVIAEEVATLPGLDGRKMSKSYNNTIPLFEGGAAGLRNATQRIVTDSRLPGEPKDAEASHLYMLYRAFSTQQESMAFRRQLEEGMGWGDAKQALYERLERDLAPMRERYVELISNPGLIEDILQAGAAKARKLAQPLVRTLRDAVGLGALQPAAAKAAQPARKAAKDARFVSFRDEDGSFRFRLLAADGEELLCSVPFANPKEAGALMRRLQDEAPEQALRGHDDVSYAAWLDGKEVAYGPQAADAGARDALLAKAREALAQLAAA
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STRAW
Sequence: MPKNKSHSGASKRFKVTGSGKVLRERAGKRHLLEHKSSRLTRRLTGNAEMAPGDAKKIKKLLGK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ASTD_SHESW
Sequence: MTHYIQGQWHTGNGHDVTSINPANGETIWCGKTATAEQVNAAVEAARAAQFDWFMLGFDARLAIVEAYRSQLEANKAELAETIAQETGKPQWETATEVGAMIGKIALSAAAYHKRTGTEANDTPAGRAVIRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVIFKPSELTPKVAELMVTLWDKAGLPAGVINLVQGEVDTGKALASHPQIDGLFFTGSSRTGHLLHQQYAGHPGKILALEMGGNNPLIIKGVQDIKAAVHDILQSAYISSGQRCTCARRLYVEQGEQGDALIALLVDAVKQIKVGPWNAQPQPFMGSMISETAAKGMVAAQANLLDLGGKVLVELTHLQAGTGLVSPGLIDVTAIDVLPDEEYFGPLLQLVRYGDFDQAIKLANQTRYGLSAGLLADSREDYDYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADAVSLPATLSPGLSL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: PYRF_WICAN
Sequence: MVQTLTYPQRAEAHPSPLAKRLFGVMESKKSNLCASIDVRTTKEFLELVDTLGPYICLVKTHIDIIDDFSIEGTIEPLKKLASKHNFLIFEDRKFADIGNTVKAQYSGGAFKIATWSDITNAHGVTGEGIVRGLKEAASEVSQEPRGLLMLAELSSKGSLAKGEYTKQTVDIAKTDKDFVIGFIAQNDMGGRDEGFDWLIMTPGVGLDDKGDGLGQQYRSVSEVVAGGSDIIIVGRGLFGKGRDPKVEGERYRSAGWNAYLKRTSQI
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: PANCY_TRIV2
Sequence: MRLLTTVAALRCYLNKRRWESQLTASEEQILDSMTSWYQTAIGLVPTMGSLHQGHLSLIERARHENSTVIVSIFINPLQFGPNEDYGRYPRTLEQDRQLCEQAGVDAIFAPSPEELGIPQKNIQESQVTQVIPPSVMISGLCGHSRLGHFQGVATIVTKLLNLVQPDRAYFGQKDGQQLAVIKRLVADLNLPVEIVACPTVREASGLACSSRNQYLTAPEKQQAAVLYRGLLQAEAAFKAGVRYSSRLREVVRQELAKVSSVLVEYIELVEPTTLMPLDKIQEEGMLAIAARLGSTRLIDNTILRDRQPIIAIDGPAGAGKSTVARQVATKLGLVYLDTGAMYRAVTWLVLQQGIAIDDDCAIAELANNCKIELTPSQDLQSPVRVWINDTDVTQDIRTIEVTSQVSAIAAQAAVREALVKQQQRWGKRGGLVAEGRDIGTHVFPDAEVKIFLTASVGERARRRQQDFQKQGQPEVSLEQLEKDIAERDWKDSTRKVSPLQKAADAVELQTDGLSISDVASQIVDYYQQRLSQW
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX2_CRIGR
Sequence: MAGREKTKSANRVLRISQLDALELNKALEQLVWSQFTQCFHGFKPGLLARFEPEVKACLWLFLWRFTIYSKNATVGQSVLNIQYKNDFSSNSRYQPPSKNQKLWYAVCTIGGRWLEERCYDLFRNRHLASFGKVKQCMNVMVGLLKLGELINFLIFLQKGKFATLTERLLGIHSVFCKPQNIREVGFDYMNRELLWHGFAEFLIFLLPLINIQKFKAKLSSWCIPLTGAASSDSALASSGKECALCGEWPTMPHTIGCEHVFCYYCVKSSFLFDMYFTCPKCGIEVHSVQPLKSGIEMSEVNAL
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane.  PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase.  PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-11', a modification that acts as a signal for PEX5 extraction into the cytosol (By similarity).  Required for pexophagy in response to starvation by mediating ubiquitination of peroxisomal proteins, such as PEX5 and ABCD3/PMP70.  Also involved in the response to reactive oxygen species (ROS) by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of PNPLA2/ATGL, thereby regulating lipolysis (By similarity).
What are the official names of this protein?
Peroxisome biogenesis factor 2, Peroxin-2, Peroxisomal membrane protein 3, Peroxisome assembly factor 1, PAF-1.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: SYI_SHESR
Sequence: MSDYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANGSIHIGHSVNKILKDIIVKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKISAAEFREECRKYAAEQVDGQRADFIRLGVLGDWQKPYLTMDFATEANIVRSLSKVIENGHLHKGVKPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFTATDSKALAAQFGVSDYSHPVAMVIWTTTPWTLPANRALSISPELDYSLVEFVKDGATHAVILADVLVEACMTRYGAESHNVLGKVKGAALELVRFKHPFLAFDVPAILGDHVTTDAGTGVVHTAPGHGQDDFVVGQKYGLEVANPVGDNGVYKPDTEFFAGQHVFKANDNVVALLKEKGALLHHVAYRHSYPHCWRHKTPIIFRATPQWFISMDNQNLRKQALSEIEQTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLFVHRETEELHPDSVSLMARVANRIEQEGIQAWWDLDAAELLGEEAEQYRKVTDTLDVWYDSGSTFASVVGARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMTGKAPYKQVLTHGFTVDGKGRKMSKSIGNVIAPQQVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRNTARFLLANLNGFDPAKDLVAVEDMVALDRWAVRRAAALQQEIIEAYEQYNFHIVTQKLMQFCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALFHIAEAMVRWIAPILSFTADEVWQLLPGQRDAYVFTQEWYQDLQSITLDTDLSDAYWDNLLTVRNEVNKVIEQARRDKRIGGSLEAEVTLFADAALTEQLTHIGDELRFVLLTSEAKVLPLADATSDAVETELASLKLVVNATTAEKCERCWHHREEVGTIEAHPTLCHRCVTNIEGDGEVRLFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_RHOP5
Sequence: MAKDSTGRMRVTVKSAGRMKLSSKLWLERQLNDPYVAQAKRDGYRSRAAYKLLEIDDKHHFLKPGASVVDLGAAPGGWSQIAAKRVGATEGKGKVVAIDLLEMPEIVGVTFAQLDFLSPAAPEKLLAMIGGRVDVVMSDMAANTTGHRKTDQLRIVGLVEDAAAFACDVLKPGGTFVAKVFQSGADATLMTQLKRDFASVKHLKPQASRKDSSERYVLALGFRGPETTNWSNPPD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_RHILO
Sequence: MTVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVVAIDRDPDAIAAGRDLEVQSGGRLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERGFSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLGEERHAGRIARMIEARREKKPFEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGRLVVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPRARSARLRAAIRTEAPARAGDFSIFGLPKLPGIDRPGER
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ES1SA_LITSE
Sequence: GLFSKFNKKKIKSGLIKIIKTAGKEAGLEALRTGIDVIGCKIKGEC
What is the function of this protein?
Mast cell degranulating peptide.  Causes histamine release from rat peritoneal mast cells in vitro.  Has antibacterial activity against the Gram-negative bacterium E. coli K12 and Gram-positive bacterium M. luteus NCT C2665.
What are the official names of this protein?
Esculentin-1SEa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ITB2_PIG
Sequence: MLCRCSPLLLLVGLLTLRSALSQECAKYKVSTCRDCIESGPGCAWCQKLNFSGQGEPDSVRCDTREQLLAKGCVADDIVDPRSLAETQEDQAGGQKQLSPQKVTLYLRPGQAATFNVTFRRAKGYPIDLYYLMDLSYSMLDDLINVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKECQAPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKSSNEFDYPSVGQLAHKLAESNIQPIFAVTKKMVKTYEKLTDIIPKSAVGELSEDSSNVLELIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVSQVNQPRGDCDGVQINVPITFQVKVTASECIQEQSFVIRALGFTDTVTVRVLPQCECRCGDSSKERTLCGNKGSMECGVCRCDAGYIGKHCECQTQGRSSQELEGSCRKDNSSIICSGLGDCICGQCVCHTSDVPNKKIYGQFCECDNMNCERFDGQVCGGEKRGLCFCSTCRCQEGFEGSACQCLKSTQGCLNLQGVECSGRGRCRCNVCQCDFGYQPPLCTDCPSCQVPCARYAKCAECLKFDTGPFAKNCSAECGTTKLLPSRMSGRKCNERDSEGCWMTYFLVQRDGRDNYDLHVEETRECVKGPNIAAIVGGTVGGVVLVGIFLLVIWKVLTHLSDLREYKRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAER
What is the function of this protein?
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.  Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL.  Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen.  Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain.  Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.  Integrin ITGAM/ITGB2 is also a receptor for factor X.  Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1.  Contributes to natural killer cell cytotoxicity.  Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils.  Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.  Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.
What are the official names of this protein?
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS7B_YEAST
Sequence: MSSVQSKILSQAPSELELQVAKTFIDLESSSPELKADLRPLQIKSIREIDVTGGKKALVLFVPVPALSAYHKVQTKLTRELEKKFPDRHVIFLAERRILPKPSRTSRQVQKRPRSRTLTAVHDKVLEDMVFPTEIVGKRVRYLVGGNKIQKVLLDSKDVQQIDYKLESFQAVYNKLTGKQIVFEIPSQTN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  eS7 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).
What are the official names of this protein?
40S ribosomal protein S7-B, Small ribosomal subunit protein eS7-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: CMOB_ECOHS
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDPHDPSKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SYY_CHLTB
Sequence: MQQLIDNLKKRGILDNSSAGLESLTVPVSAYLGFDPTAPSLHIGHWIGICFLRRLAAYGITPVALVGGATGMIGDPSGKSVERSLLDQAQVLDNSKKIAAALASYLPGIRIVNNADWLGSLSMVDFLRDVGKHFRLGSMLAKDVVKQRVYSEEGISYTEFSYLLLQSYDFAHLFKEHNVVLQCGGSDQWGNITSGIDYIRRRGLGQAYGLTYPLLTDSKGKKIGKTESGTIWLDPALTPPYELFQYFLRLPDQEISKVMRTLTLLDNEEIFALDERLTSDPQAVKKYIAEVIVKDVHGSEGLAQAQAATESFFASKGKSITEAELVALVESGVGVKVARADLIGKRWLDIVVELGFCSSRGQARRLIQQRGLYINQEPLADEQSILDGTQLCFDRYVLLSQGKRKKQVIDLN
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM4A_MOUSE
Sequence: MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGGLTPRAGSEECPEEDVEAADQGEEGDVKRSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEELSSGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFEELKNVKLEEEDEEDEPEAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSTSSQDSVSSDSETAESVSCQGQEKTGVLTVHSYARGDGKAATGEPSVKKKRSAPRSISEQELAEVADEYMLSLEENKKTKGRRQPLSKLPRHHPLVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQVEFGAFSQSCGDASEPAAQTQRTKPLIPEMCFTTTGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code (PubMed:24953653).  Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'.  Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues.  Demethylation of Lys residue generates formaldehyde and succinate.  Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIKR_PYRHO
Sequence: MELIRFSISIPSKLLEKFDQIIEEIGYENRSEAIRDLIRDFIIRHEWEVGNEEVAGTITIVYNHDEGDVVKALLDLQHEYLDEIISSLHVHMDEHNCLEVIVVKGEAKKIKMIADKLLSLKGVKHGKLVMTSTGKELV
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RUS2_ACIFI
Sequence: MYTQNTMKKNWYVTVGAAAALAATVGMGTAMAGTLDSTWKEATLPQVKAMLEKDTGKVSGDTVTYSGKTVHVVAAAVLPGFPFPSFEVHDKKNPTLEIPAGATVDVTFINTNKGFGHSFDITKKGPPYAVMPVIDPIVAGTGFSPVPKDGKFGYTDFTWHPTAGTYYYVCQIPGHAATGMFGKIIVK
What is the function of this protein?
Electron carrier from cytochrome c552 to the A-type oxidase.
What are the official names of this protein?
Rusticyanin.
What are the subcellular locations of this protein?
Periplasm.
Protein: CWP17_ARATH
Sequence: IPCRKAIDVPFGXRYVVXTW
What are the official names of this protein?
23 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HECD2_MOUSE
Sequence: MSEAARDLSPGAPPAVAAAAPEERKGKEPEREKLPPIVTAGAAAGLDRGSKGQISTFSSFVSTVTQKKEAAENRSSPTHLALPNIRNVRDLPPICLDVRQKQRMSVEALPSEVKVPPLPEPSLPSQPKTVKDFEEDLEKAEATGNWKTVHAFYITAFDSFTELNTAFKKDATASFNTIEDSGLNANLVNAVFDALLNTPQDIQKSVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNITSTYVIYAHLLRQIATLVEADHHFLVHWLKKLSQKKFKQLVERLLQFVSLRLFPAKPEEFPPLTKCTWWIPSAAKVLALLNTANNLVHPPLVPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQSTPVGICSVTIDDLCQVMPELAHGLKELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPGGDKIPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase HECTD2, HECT domain-containing protein 2, HECT-type E3 ubiquitin transferase HECTD2.