PharMolix/UniProtQA huggingface dataset:
Protein: ENO_JANMA
Sequence: MSAIVDIIGREVIDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKSRYFGKGVLKACEHINTEISEAIMGLDANEQAFLDRTLIDLDGTENKARLGANATLAVSMAVAKAAAEESGLPLYRYFGGSGAMQMPVPMMNVINGGAHANNNLDLQEFMIIPVGAPSFREAIRYGAEVFHTLKKIINDKGLPTSVGDEGGFAPSVENHEAAIKLILQAIEQAGYEPGTQIALGLDCAASEFYKDGKYHLAGEGMTLSSADFTNLLGTWCDKYPIISIEDGMAENDWDGWATLTNALGKKVQLVGDDLFVTNTKILREGIQKNIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNSLQIKTGSMSRSDRMAKYNQLLRIEEDLGDIASYPGRGAFYNLK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PRIL_METBU
Sequence: MDNRHLALYPFVTEASEYVGSLGFSPDKLLSSRALESARIRGRERVIQALEGEIEKPSPSSSEEGKILTELLSYPFSRILVSCIDDPFLTRKYALAEAKAAYHLLKTQQPEFLQDLATDFRINAEIYENPETHDIFFDLHFTDYIKLASPLKDLNWKLVNRKMKKGYVKISKEELARLLQEAIRLRIQNSLPVTVPKEICEACIPHTDTISEELEKKKTEFGVGEFQRVESDLFPPCITQAIANVRAGVNLAHSMRFAMTSFLINIGMSVDEVVAMFNISPDFDEEKTRYQIEHIAGTSSGTTYKPPSCNTMRTYGNCSAPDELCKGVKHPLGYYSRRVWVKNRMQNDNEKGHEEKKEGETPPQ
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: ANM1_SCHPO
Sequence: MPGNTKKSADSGLTAKDYYFDSYSHWGIHEEMLKDDVRTLSYRDAIMQNPHLFRDKIVLDVGCGTGILSMFCARAGAKHVYGVDMSEIIHKAVQIVEVNKLSDRITLIQGKMEEIQLPVEKVDIIVSEWMGYFLLYESMLDTVLVARDRYLAPDGLLFPDRAQIQLAAIEDADYKSEKIGFWDDVYGFDFSPIKKDVWKEPLVDTVDRIAVNTNSCVILDLDLKTVKKEDLAFSSPFEITATRNDFVHAFLAWFDIEFSACHKPIKFSTGPFSRYTHWKQTVFYTHKDLTVKAGEYIRGTITCKPAEGNHRELDIDISYTFNPREPNREPVSEDLSYRMC
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity).  Asymmetrically dimethylates the polyadenylate-binding protein pab2, modulating pab2 oligomerization (PubMed:17213188).
What are the official names of this protein?
Protein arginine N-methyltransferase 1, Type I protein arginine N-methyltransferase, Type I PRMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_BORBR
Sequence: MAFFGKRKEKRKFTQQNPLFKRRKFCRFTAAGVEEIDYKDLDTLRDFVQENGKIIPARLTGTRAIYQRQLDTAIKRARFLALLPYTDNHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HFQ_SYMTH
Sequence: MTKASASLQDGFLNLLRRENIPATIYLVNGYQLKGYIRGFDNFTVAVEVDGRVQLVYKHALSTITPARPLPVSVSQIMRAGEGQEVEGEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PYRH_BRASB
Sequence: MAEPVYRRVVVKLSGEYLAGPHSFGIDQATVDRIADDLIAAQKLGIEIAVVVGGGNMVRGVEVSSQGVSRPTGDTMGMLATVMNCLALEAAIQRKGAPAQALSAFVMPQVCELFTRAAAHKALAEGRIVVLGGGTGNPYFTTDTTAVLRAAEIGAQAVLKATNVDGVYSADPKKDPAAKRFDRLTHSQAIEGGYKVMDATAFALARETSLPIIVFSIAEPGAIGAMLRGEGRGTIVAG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK2_STRCO
Sequence: MNPVNYLYLAALLFTIGATGVLIRRNAIVVFMCIELMLNACNLAFVAFSRMHGNLDGQIIAFFTMVVAAAEVVVGLAIIVSLFRSRHSASVDDASLMKL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG8_ASPFU
Sequence: MRSKFKDEHPFEKRKAEAERIRQKYADRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGDC
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier atg8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: FETP_CITK8
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNVEHRKLLEQEMINFLFEGKDVHIEGYTPEEKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: SSRP_FRATN
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCVPLAMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: THIO_CHLTR
Sequence: MVQVVSQENFADSIASGLVLIDFFAEWCGPCKMLTPVLEALAAELPHVTILKVDIDSSPRPAEQYSVSSIPTLILFKDGKEVERSVGLKDKDSLIKLISKHQ
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: ERPA_FRATM
Sequence: MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: MUTS_KLEP7
Sequence: MSTIDNLDAHTPMMQQYLKLKAQHPDILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATTKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAESSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGTDNTLASVLDCTVTPMGSRMLKRWLHMPVRDTAVLVERQQTIGALQERYTELQPVLRQVGDLERILARLALRTARPRDLARMRHALQQLPLLRELLADVDSQPVQKLREKMGEFTELRELLERAVIDAPPVLVRDGGVIAPGYSEELDEWRALADGATDYLDKLEIRERERLGLDTLKVGYNAVHGYYIQISRGQSHLAPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQTSASALAELDVLVNLAERAETLNYCCPTFSDKPGIRISEGRHPVVEQVLKEPFIANPLQLAPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEHSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1195_GEOKA
Sequence: MLEKTMRMNYLYDFYQALLTPKQRNYMALYYLDDYSLGEIAEQYEVSRQAVYDNIRRTEAMLEQYEEKLGLLRKYERRRQIIERLKDYISRRYGADAELAALVRELDELD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein GK1195.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: ASCL4_HUMAN
Sequence: METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEPEEGGS
What is the function of this protein?
Could be a transcriptional regulator involved in skin development.
What are the official names of this protein?
Achaete-scute homolog 4, ASH-4, hASH4, Achaete-scute-like protein 4, Class A basic helix-loop-helix protein 44, bHLHa44.
What are the subcellular locations of this protein?
Nucleus.
Protein: VGAM_HAEIN
Sequence: MATKVKSQAKLRFVSVEQVQSAIKEIGDLSREHTRLATEMNDKIGATSEHYAPKLKALKEEIEPLQKAVQEYCEANRDELTEFGKTKTANFVTGEVQWRQRPPSVAIRGAEAVMEFLQRMGFDRFIRTRQEINKEALLNEPEVAKGIAGVTIKQGLEDFVIKPFEQDAR
What is the function of this protein?
Protects linear double-stranded DNA of Mu genome from exonuclease degradation.
What are the official names of this protein?
Mu-like prophage FluMu host-nuclease inhibitor protein gam.
What is the protein family that this protein belongs to?
To phage Mu protein gam.
Protein: CCA_METFK
Sequence: MRIYTVGGAVRDRLLGLPVKDRDHVVVGSTPEAMVQLGYRPVGKDFPVFLHPVTHEEYALARTERKTGKGYKGFQVHADPEVTLEQDLARRDLTINAIAEDEHGNLIDPYHGVADLHAKVLRHVSPAFCEDPVRILRVARFAARFVEFSVADETMTLMRHMVEDGEVDALVPERVWQELAKGLMEQRPSRMFEVLRACGALKRLLPELDRLFGVPQTAKYHPEIDTGVHVMLVIDYAARAGFSLPVRFAALTHDLGKGTTPAHILPRHIGHEERSVELLQSLVKRLRVPNDCKDLALLVAKHHGKVHQVGEMKAATVLRFLQETDALRQPGRFRDFLSACEADARGRTGFEQQALPLFPLLLEILQLVRTVDAGAIAREQSSPDAIKEAVFSARVAAMEAAYRFPLKEAVG
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: NU4C_SYNPW
Sequence: MLEFAVSAPFDPAADISAGIIPAQFPWLSLSILFPIVGSLMVPFIPDQGDGRQVRWFALGIALTTFLITVAAYLNGYDPSFSGLQLSERVSWLPNLGLTWAVGADGLSMPLILLTSFITTLAVLAAWPVTFKPKLFFFLMLAMDGGQIAVFAVQDMLLFFLAWELELLPVYLLLAIWGGKKRQYAATKFILYTAGSSLFILLAALAMGFMGGGTPNFEYAVLAQKGFSTSFQLLCYAGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRFNAEMLPDAHAQFAPLLVVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSALGTSGAMLQMISHGLIGASLFFLVGATYDRTHTLQLDEMGGVGQKMRIMFALWTVCSLASLALPGMSGFVSELMVFTGFATDEAYTLTFRIVIDGLAAVGVILTPIYLLSMLREIFFGKENVQLASNTNLVDAEPREVYIIGCLLVPIIGIGLYPRLMTDSYRTAIEALVDRDVAAMETISRPTAPLIRNPSLAPALLQAPKLP
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ISAB_STAAB
Sequence: MNKTSKVCVAATLALGTLIGVTVVENSAPTSKQAQAAITPYYTYNGYIGNNANFILDKNFINAIKYDNVKFNGIKLAKTNTIKKVEKYDQTFKGVSAKGNEASQLQFVVKNNISLKDIQKAYGKDLKKENGKTKEADSGIFYYQNAKKTLGIWFVVDHNRVVEVTVGHTPYKTSK
What are the official names of this protein?
Immunodominant staphylococcal antigen B.
What is the protein family that this protein belongs to?
Belongs to the IsaB family.
What are the subcellular locations of this protein?
Secreted.
Protein: METN_XANC5
Sequence: MIQFQRLHKSYSVDGRQIVALHPLDLRIGPGEVFGIIGHSGAGKSTLIRLINRLEEPSGGRLLIGDEDVTALDGQGLRALRRRIGMIFQHFNLLSSRTVAGNVAFPLELAGTPRAEIDARVAELLARVGLQEHANKYPAQLSGGQKQRVGIARALATRPQILLCDEATSALDPQTTASVLQLLAQINRELGLTIVLITHEMDVIRRVCDRVAVLDAGKLVETGPVTEVFLHPKHATTRRFVSEAEHVDEAELHRDFAAVGGRIVRLTFLGNGTYEPVLGRIARETGVDYNILSGRVDRIKDTPYGQLIVALTGGDQNAARAGFVAAGVQVEDLRV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HAGA1_PORGI
Sequence: MRKLNSLFSLAVLLSLLCWGQTAAAQGGPKTAPSVTHQAVQKGIRTSKAKDLRDPIPAGMARIILEAHDVWEDGTGYQMLWDADHNQYGASIPEESFWFANGTIPAGLYDPFEYKVPVNADASFSPTNFVLDGTASADIPAGTYDYVIINPNPGIIYIVGEGVSKGNDYVVEAGKTYHFTVQRQGPGDAASVVVTGEGGNEFAPVQNLQWSVSGQTVTLTWQAPASDKRTYVLNESFDTQTLPNGWTMIDADGDGHNWLSTINVYNTATHTGDGAMFSKSWTASSGAKIDLSPDNYLVTPKFTVPENGKLSYWVSSQEPWTNEHYGVFLSTTGNEAANFTIKLLEETLGSGKPAPMNLVKSEGVKAPAPYQERTIDLSAYAGQQVYLAFRHFGCTGIFRLYLDDVAVSGEGSSNDYTYTVYRDNVVIAQNLTATTFNQENVAPGQYNYCVEVKYTAGVSPKVCKDVTVEGSNEFAPVQNLTGSAVGQKVTLKWDAPNGTPNPNPGTTTLSESFENGIPASWKTIDADGDGNNWTTTPPPGGSSFAGHNSAICVSSASYINFEGPQNPDNYLVTPELSLPNGGTLTFWVCAQDANYASEHYAVYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFRHFGCTDFFWINLDDVEIKANGKRADFTETFESSTHGEAPAEWTTIDADGDGQGWLCLSSGQLGWLTAHGGTNVVASFSWNGMALNPDNYLISKDVTGATKVKYYYAVNDGFPGDHYAVMISKTGTNAGDFTVVFEETPNGINKGGARFGLSTEANGAKPQSVWIERTVDLPAGTKYVAFRHYNCSDLNYILLDDIQFTMGGSPTPTDYTYTVYRDGTKIKEGLTETTFEEDGVATGNHEYCVEVKYTAGVSPKECVNVTVDPVQFNPVQNLTGSAVGQKVTLKWDAPNGTPNPNPGTTTLSESFENGIPASWKTIDADGDGNNWTTTPPPGGTSFAGHNSAICVSSASYINFEGPQNPDNYLVTPELSLPNGGTLTFWVCAQDANYASEHYAVYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFRHFGCTDFFWINLDDVEIKANGKRADFTETFESSTHGEAPAEWTTIDADGDGQGWLCLSSGQLDWLTAHGGTNVVASFSWNGMALNPDNYLISKDVTGATKVKYYYAVNDGFPGDHYAVMISKTGTNAGDFTVVFEETPNGINKGGARFGLSTEANGAKPQSVWIERTVDLPAGTKYVAFRHYNCSDLNYILLDDIQFTMGGSPTPTDYTYTVYRDGTKIKEGLTETTFEEDGVATGNHEYCVEVKYTAGVSPKECVNVTVDPVQFNPVQNLTGSAVGQKVTLKWDAPNGTPNPNPGTTTLSESFENGIPASWKTIDADGDGNNWTTTPPPGGTSFAGHNSAICVSSASYINFEGPQNPDNYLVTPELSLPNGGTLTFWVCAQDANYASEHYAVYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFRHFGCTDFFWINLDDVEIKANGKRADFTETFESSTHGEAPAEWTTIDADGDGQGWLCLSSGQLGWLTAHGGTNVVASFSWNGMALNPDNYLISKDVTGATKVKYYYAVNDGFPGDHYAVMISKTGTNAGDFTVVFEETPNGINKGGARFGLSTEANGAKPQSVWIERTVDLPAGTKYVAFRHYNCSDLNYILLDDIQFTMGGSPTPTDYTYTVYRDGTKIKEGLTETTFEEDGVATGNHEYCVEVKYTAGVSPKECVNVTINPTQFNPVQNLTAEQAPNSMDAILKWNAPASKRAEVLNEDFENGIPASWKTIDADGDGNNWTTTPPPGGSSFAGHNSAICVSSASYINFEGPQNPDNYLVTPELSLPGGGTLTFWVCAQDANYASEHYAVYASSTGNDASNFANALLEEVLTAKTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFRHFGCTDFFWINLDDVVITSGNAPSYTYTIYRNNTQIASGVTETTYRDPDLATGFYTYGVKVVYPNGESAIETATLNITSLADVTAQKPYTLTVVGKTITVTCQGEAMIYDMNGRRLAAGRNTVVYTAQGGHYAVMVVVDGKSYVEKLAVK
What is the function of this protein?
Agglutinates erythrocytes.
What are the official names of this protein?
Hemagglutinin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C25 family.
Protein: Y2219_YERPA
Sequence: MEIRIFQQDDFEEVILLWEHCDLLRPWNDPEMDIERKLNHDPELFLVAEVNGTIVGSVMGGYDGHRGSAYYLGVHPDYRGRGFANALISRLEKKLIARGCPKLNIMVREDNDAVIGMYEKLDYETQDTIMLGKRLIVDQEY
What are the official names of this protein?
Acetyltransferase YPA_2219.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: ISCS_KLEP3
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFLTMDGTFGNPASRSHRFGWQAEEAVDIARNQIAELVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIATIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRIRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMESEMARLRGLRDRLWNGVKDMEEVYLNGDLEQGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGMTDELAHSSIRFSLGRFTTEEEIDYTINLVRNSIGRLRDLSPLWEMFKQGVDLNSIEWSHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_SYNE7
Sequence: MIAATPMPLLKQPDRLEARLRELPAEPGVYFMRDASDRILYIGKSKKLRSRVRSYFRDLERLNPRINLMVRQVCEIEIIVTDTEAEALALEANLIKQHQPHFNVLLKDDKKYPYLCITWSDDYPRIFITRKRRLGNSRDRYYGPYVDTRLLRHTLFLVKRLFPLRQRPQPLFKDRTCLNYDIGRCPGVCQSLIRPDDYRKTLQKVAMIFQGRSSELVELLEAQMLQAAENLEFEKAAKIRDQIRGLEGLGAEQKVQLPDDRISRDAIALAMDEQHACIQLFQIRAGKLVGRLGFVADAQSGSAAAIAQRVLEEHYASVDSVEIPQEVLVQHDLPEAELLEVWLSERRGRKVEILSPQRQIKADLIAMVERNAEYELARTQQSAERHTASLIDLADLLDLPELPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPEVRAGHSDDFASLAEVLHRRFRKFAEAKARGESLAPSEQRQGSLLRPDDLADFPDLVMIDGGKGQLSAVVEVLRNLNLLEDVKLCSLAKKREEIFLPGASDPLPTDAEQPGVQLLRRLRDEAHRFAVSFHRQKRTERMRRSRLDDIPGLGHKRQKELLAHFRSIDYLRLATPEQIAEVPGIGAVLAQQIWGYFHPSETA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIMP1_MOUSE
Sequence: MMAPFASLASGILLLLSLIASSKACSCAPPHPQTAFCNSDLVIRAKFMGSPEINETTLYQRYKIKMTKMLKGFKAVGNAADIRYAYTPVMESLCGYAHKSQNRSEEFLITGRLRNGNLHISACSFLVPWRTLSPAQQRAFSKTYSAGCGVCTVFPCLSIPCKLESDTHCLWTDQVLVGSEDYQSRHFACLPRNPGLCTWRSLGAR
What is the function of this protein?
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor.  Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.  Does not act on MMP14 (By similarity).  Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1.  Plays a role in integrin signaling.
What are the official names of this protein?
Metalloproteinase inhibitor 1, Collagenase inhibitor 16C8 fibroblast, Erythroid-potentiating activity, EPA, TPA-S1, TPA-induced protein, Tissue inhibitor of metalloproteinases 1, TIMP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CFI_PYRCO
Sequence: MAPPPSLAGLQVEATAFPPSVKPPGSSNTLFLGGAGVRGLEIQGNFVKFTAIGVYLEDNAVPLLAVKWKGKTAEELSESVEFFRDIVTGPFEKFIQVTTILPLTGQQYSEKVSENCVAFWKSVGIYTDAEGKAIEKFIEVFKDQNFPPGASILFTQSPKGSLTICFSKDASVPEAANAVIENKLLSEAVLESILGKHGVSPAAKRSLAARLSELLNGCK
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.