PharMolix/UniProtQA huggingface dataset:
Protein: SYGA_PARDP
Sequence: MTSPKDNQTAKPVCFQDVILRLQSYWAAQGCAVLQPYDMEVGAGTFHPATTLRSLGARPWAAAYVQPSRRPTDGRYGENPNRLQHYYQYQVIIKPSPPNLQELYLGSLAAIGLDPMIHDVRFVEDDWESPTLGAWGLGWEVWCDGMEVSQFTYFQQVGGHDCRPVSGELTYGLERLAMYVLGVEHVMDMPFNPPGSPIPLSYGDVFRQAEREYSRWNFEQADTGMLLQHFKDAEAECDRILTAAETDSAGRRIPMAHPAYDQAIKASHLFNLLDARGVISVTERQAYIGRVRALAKRCADLFVTTEAATLQAEDAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_XANP2
Sequence: MRSYLDFEKPVAELEAKVEELRALASAGDGVTITDEVQRLETKAREALLALYANLTPWQKTLVARHPQRPHFADFAKGLFEDFTPLAGDRKFGEDEAIIGGFARFRGEAVCVLGHEKGSTTETRIRHNFGMARPEGYRKAVRIMELADRFGIPLISLVDTAGAYPGIGAEERGQAEAIARSTDACLALGAPNVALVIGEGGSGGAIAIATANKVLMMEHAIYSVISPEGAASILWRDTAKAQEAATNMKITAQDLLKFGIIDAIVKEPPGGAHRDPEATIGAAGDAIADALSQLAGLDGPAVRKARRDKFLAIGRSL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR6X1_HUMAN
Sequence: MRNGTVITEFILLGFPVIQGLQTPLFIAIFLTYILTLAGNGLIIATVWAEPRLQIPMYFFLCNLSFLEIWYTTTVIPKLLGTFVVARTVICMSCCLLQAFFHFFVGTTEFLILTIMSFDRYLTICNPLHHPTIMTSKLCLQLALSSWVVGFTIVFCQTMLLIQLPFCGNNVISHFYCDVGPSLKAACIDTSILELLGVIATILVIPGSLLFNMISYIYILSAILRIPSATGHQKTFSTCASHLTVVSLLYGAVLFMYLRPTAHSSFKINKVVSVLNTILTPLLNPFIYTIRNKEVKGALRKAMTCPKTGHAK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6X1, Olfactory receptor OR11-270.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SWT14_ORYSI
Sequence: MAGMSLQHPWAFAFGLLGNIISFMTYLAPLPTFYRIYKSKSTQGFQSVPYVVALFSAMLWIYYALLKSDECLLITINSAGCVIETIYIAVYLVYAPKKAKMFTAKLLLLVNVGVFGLILLLTLLLSAGDRRIVVLGWVCVGFSVSVFVAPLSIIRLVVRTKSVEFMPFSLSFSLTISAVVWFLYGLLIKDKYVALPNVLGFSFGVIQMGLYAMYRNSTPKAVLTKEVEAATATGDDDHSAAGVKEHVVNIAKLSAAVDVVKTREVHPVDVESPPAEAPPQEDDKAAAATAAAVAGAGEKKVAA
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET14, OsSWEET14.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLB3_TYLHE
Sequence: DDCCSAADRHEVLDNWKGIWSAEFTGRRVAIGQAIFQELFALDPNAKGVFGRVNVDKPSEADWKAHVIRVINGLDLAVNLLEDPKALQEELKHLARQHRERSGVKAVYFDEMEKALLKVLPQVSSHFNSGAWDRCFTRIADVIKAELP
What are the official names of this protein?
Extracellular globin-2B, Erythrocruorin, Extracellular globin IIB.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR2_DIOEL
Sequence: MKRRYWNINLPEMMEAGVHFGHGTKKWNPRMAPYISAKRKGIHITNLTITARFLSEACDLVFDAASRGKSFLIVGTKNKAADSVASAAIRARCHYVNKKWLGGMLTNWSTTETRLHKFRDLRAEQNMGKLNRLPKRDAAMLKRKLSALQSYLGGIKYMTGLPDIVIIVDQEKEYMALQECAILGIPTICLIDTNCNPDLADISIPANDDAIASIRLILNKLVFAICEGRYSYIGNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM6_PHOLL
Sequence: MNTPNINQIKSFFLSLQDEICQQLEQIDGKEKFTEQCWQREEGGGGRSRIMKEGTIFEQAGANFSHVSGDMLPLSATAHRPELVGRHYQAMGVSLVIHPLNPYIPTSHANVRFFIAEKEGEAPVWWFGGGFDLTPYYGFKEDAIHWHTTARNICRPYGEDVYPKYKEWCDNYFYIKHRNEARGIGGLFYDDLNTPDFEHCFNFTQDIGKGFLSAYLPIVEKRKEILWGERERQFQLYRRGRYVEFNLVWDRGTLFGLQSGGRTESILMSMPPLARWEHDYHPEPESAEAALYTDFLPAKNWI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_RICAH
Sequence: MFNEITKSVTWNGKVLELSTGKIARQADGAVTVKMGNSVLLCAAVVANKAKEGIGFFPLTINYREMAYAAGKIPGGFFKREGKASDREVLVSRLIDRPIRPLFHPAFVNETHVTCTVLSYDPETPVDILAIIGASAALSLSPAPYLEIVAASKVGLIDGEFVLNPTLELLKTSQLDLVVAGTADSVMMVESEANLLSEEQMLEAVKFGFESFQPIIKIIKELAKEAKKPKFQMQDLYPASLKKEIEKLFVKEIKQAFAIKSKQERSTNLDLIHEKVLTHFVSDIENKKYSNYQIESALKSIESDILRNEILEKNRRIDGRSTTDIRQIACEIGLLPSAHGSALFTRGETQSLVSTTFGTSLDEQLVDSLDGEYKERFMLDYIFPPYSVNEAMPMKAPSRREVGHGKLAWRAINPILPNKVQFPYAIRVVAETTESNGSSSMATVCSSSLALMYAGVPIKAPVAGIAMGLVKEGKKFAVLSDILGDEDYFGDMDFKVAGTSEGITALQMDIKISGVDFKIMKAALEQARLGRLHILDQMNKIISKPNSKLGKNVPSTTTIKIDKDKIRDVIGPGGKVIKEICETSDAKIDISDDGTVSVYASDRDKLKVALDKIKAIAVEPEIGEIFNGTVMKVLDSGAFINYLGTKDGFVHISEIAEERIETVGSVLKQGDIVKVKLIGFDNKGKAKLTIKNADKDKSSNNPKQKNNVNNSKENSEPERRDSSKKRAWNEDNNSDTTEVITERKYFN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_SHEAM
Sequence: MQEQYIHSEIEAEVQKYWADNKTFEVTEDPAKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARFQRLQGKNVLQPIGWDAFGLPAENAAIKNATAPAPWTYENIDYMKNQLKMLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTSAVNWCPNDQTVLANEQVQDGCCWRCDTPVEQKEIPQWFIKITAYAEELLNDIDNLEGWPEQVKTMQRNWIGRSEGVEMTFKVKDSDDSFDIYTTRPDTVMGVTYVAIAAGHPLAEKAALNNPELAAFVEECKQSGTSEAELATMEKKGVATGLYAIHPLTGEEVPVWAANFVLMNYGTGAVMSVPAHDQRDYEFAKKYGLALKAVIKPADGEVDISEAAYTEKGVLFNSAEFDGLDFDGAFNAIADKLAAEGKGKRQVNFRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILPEDVVMDGVQSPIKADKEWAKTQVNGQDALRETDTFDTFMESSWYYARYCSPKANEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDAGLVNSNEPAKRLLTQGMVLADAFYYNNEKGARVWVSPLDVTVVEKDDKGRILKAVDTEGHELVYTGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASEYSAAPATEALDVSALNADQKTLRRELHKTIAKVTDDLGRRQMFNTAVAAVMELMNHLQKAPLASAQDKALMNEALSAVVRLLYPIAPHVCFNLWRELGNSGAIEDAGWPATDESALVEDSKLIVVQVNGKVRAKLTVAADATKEQVEALGLAEDAVRKYTDGVTVRKVIYVPGKLLNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAA6_CAEEL
Sequence: MKSKRRDDIVQFCRENTLLVMTMFSVFLGVVLGFGLRPLNLSQETLQLINFPGEIFMQVLKMMILPLIFSSLISALAQMDAKESGQMGASTVLYYLSTAVLATILGIFLVTVIHPGDPSIKGTDISEAPSDGNVSPLDTFLDLVRNMFPENIIQATFERMQTTYVAIRPKIASKNGTSGNIIVKRSIGMTKGMNILGIIVFCTGFGIVISQLGERARIVVDFFVILDAVIMRWVVTLMWFAPLGITCLICGNLLELDDISDIASVLALYVFTVCAGLILHTIITVPLMYFFITRENPLPIFKGMIQAAVTAFGTASGGATLPMSMQCLEDHCGVDRRISRFVLPLGSTINMDGNALYEAVAVIFIAQLNNVQLSLAEVLTVSITATIASIGLGSVPAGLVSILLILNTVGLPVRDVSMLFTVDWLLDRVRTAVNVLGDAFAASMVQHLLQKKLDQADARHDYKTELKGEIELLKSAATSRRPSFTMSEASKELFLTHANTAGNSRIGSRIGSRRPSSTNLHLSWRNNNIEPPYTPLPNDENV
What are the official names of this protein?
Putative sodium-dependent excitatory amino acid transporter glt-6.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARRC_LITCT
Sequence: MADGSKVFKKTSPDGKITVYLAKRDYVDHVEFVEPVDGMIVIDPEYQKEKKVFVMMTCAFRYGRDDMELIGLSFRKDIYVQSCQVHPPLPGEKKALTPLQEKLKAKLGGNSFPFSFNMATNLPCSVTLQPGPEDSGKACGVDFEVKGFWGDDVEEKNSKKNVARLIIRKVQYAPETSGAAPHAEITKQFMMSDKPLQLEASLNKEIHYHGEPIIVNVKINNSTNKIVKKIKITVEQITDVVLYSLDKYTKVVCCEEMNDTVAANSAFTKAYQVTPLLANNREKRGLALDGKLKHGDTNLASSTTLRPGMDKEVMGILVSYKIRVNLMASRGGILGDLISSDVSVELPLILMHPKPAEGTTSAEDVVIEEFARQKLQGEQDDEEDKEEAS
What is the function of this protein?
May play a role in an as yet undefined retina-specific signal transduction.  Could bind to photoactivated-phosphorylated red/green opsins.
What are the official names of this protein?
Arrestin-C, Cone arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: ACCD1_LACPJ
Sequence: MSHYPASGTWQACPKCGRHVHQRQWGTYQQCPYCHYWQRLTTAQRLEQLVDEGSFQPLTMTERPVNQLGFPDYTNKLRRAQRQTGLNEAVVCGTALIEQQPCILAVMDSHFMMGTLNTAVTRRLLHASEQARAQRLPLIIVTASGGARMQEGVYALVGMNLILAELARLAATPLPLITVLTDPTMGGVSASFAFKGDLIIAEAGAKIGFAGARVIQQTLPVKLPADFQTADQLFKNGMVDAVVERPQLRSTLGQALANYGIGRSAHG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1, ACCase subunit beta 1, Acetyl-CoA carboxylase carboxyltransferase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_MORIN
Sequence: MGQEKVTVSTRPLQWKCVESRADSKRLYYGRFLLAPLMRGQADTIGIAMRRALLGEIEGTCITRAKSEKIPHEYSTIVGIQESVHEILMNLKEIVLRSNLYGTRDASICVKGPGYVTAQDIILPPSVEIVDNTQHIANLTEPITLCIELQIERNRGYRIKTPNNFQNGSYPIDAVFMPVRNANHSIHSYVNGNENQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFFHAEEHLENNQHKGTLPLFNFHGRLAKPRKTKKEIALKYIYIDQSELPPRVYNCLKRSNINTFLELLNNSQEELMKIQDFRIEDVKHILDVLEI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_GEODF
Sequence: MAIKSYKPTSAGRRHQTCSTFEEITTSQPERSLVVKLKKTGGRNNFGRITSRHIGGGHKQKYRIIDFRRDKRDIPAKVASVEYDPYRSARIALLNYADGEKRYIIAPLDLKVGDTVVASTSADIKPGNALPIRSIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAKEEKYAQVKLPSGEVRMVLMDCMATIGQVGNLDHENVSIGKAGRSRWLGKRPKVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRTNKTSTRFIVKRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GUAA_CHLL2
Sequence: MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYNTTPETIREHAPKAIILSGGPTSVYGESAILPHEGIFSLGLPILGICYGLQAIAKHFGGEVASSAKQEFGRAKMLVSRDGEPESMLFRNIPDSDVWMSHGDKVVNLPDGFRITASSANSEMCALETYGSKGALKVFGLQFHPEVQHTLYGKQLLSNFLIDIAGITPDWSPKHFIDHQIEEIRRTAGDETVICGISGGVDSSVAAVLVSRAIGKNLHCVFVDNGLLRKNEADKVMQFLKHLGLRLTLADASELFLKRLKNVASPEKKRKIIGRTFIQVFEEQLDKEKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRVLGSVSKERLDILRDADEIFLEELKSSGLYQKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAQLPHDFLARVSNRIINEVRGINRVAYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: QUEC_ALKEH
Sequence: MSETADTNQTAVVLFSGGQDSTTCLAWALARYHRVHTVAFDYGQRHRVELACRQRVREAIGQHFAGWGARLGEDHLLDLTSLGEISDTSLTRERAIEIRDSGLPDTFVPGRNLLFLTYAAALAWRLQARHLITGVCETDYSGYPDCRDDTIKALQVALNLGMDSHFVLHTPLMWRDKAQTWALAETLGGADLVELIAEHTHTCYLGDRTQRHDWGYGCGECPACRLRAQGWRRHRGLC
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YVLB_BACSU
Sequence: MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSVHVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKDTDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARHAFLQHIECEIKGNKFFIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSYLTAEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINVTESDCRSIYAKTTTGNVELAIPDDLAVKAELKSNLGTLSHELMDVEMLKEKNDTIQKEMMFTSNQAHDQNITVFSESLTGAIKLKYSQR
What are the official names of this protein?
Uncharacterized protein YvlB.
Protein: PG029_VACCC
Sequence: MNAYNKADSFSLESDSIKDVIHDYICWLSMTDEMRPSIGNVFKAMETFKIDAVRYYDGNIYDLAKDINAMSFDSFIRSLQNISSKKDKLTVYGTMGLLSIVVDINKGCDISNIKFAAGIIILMEYIFDDTDMSHLKVALYRRIQRRDDVDR
What is the function of this protein?
Prevents establishment of cellular antiviral state by blocking virus-induced phosphorylation and activation of interferon regulatory factors 3/IRF3 and 7/IRF7, transcription factors critical for the induction of interferons alpha and beta.  This blockage is produced through the inhibition of host TBK1, by binding host TBK1 adapter proteins TBKBP1 and AZI2, thereby producing a strong inhibition of the phosphorylation and activation of IRF3 and IRF7.  Acts also as an inhibitor of the cellular response to type I IFN by interacting with host STAT2.  Mechanistically, exerts its inhibitory effect after host ISGF3 complex (composed of STAT1, STAT2 and IRF9) binding to the interferon stimulated response element (ISRE).
What are the official names of this protein?
IFN signaling evasion protein OPG029.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG029 family.
Protein: MURG_BURP1
Sequence: MTSTQRTLMVMAGGTGGHVFPGLAVAHRMQAQGWRVVWLGNPAGMEATLVPRHGIPMEYVHFGGLRGKGLATKFALPFNLLRACAQSLRALRRVKPDVVLGMGGYITFPAGLVTVLTGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPNAEWTGNPIRTELARTEPPQARYAARSGKLRLLVVGGSLGAAALNEVVPRALALLAPDERPQVVHQAGAKHIDTLKENYEAAGLSCGSDVALVPFIDDMASAYANADLVICRSGAMTVAEIAAVGVAALFVPFPHAVDDHQTTNAEFLAEQGAAVLVQQRDLSAELLADWLRGQSRDSLAAMAERSRSLAKPDATDEVARVCAAVAGANLEGKQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y427_UREUR
Sequence: MANSQKVIDVSNAHYNLNLELGSVYAQYAHIADDQFSMPFLAKFINDLSNDKLGVHKDLISEYARKIEIPLHTKFSVDVSFKPTDPKELVKHILETEQKVRKHVANMAKVCLEEGDFETFSFVKWFVDDGIKDFDDVRTIHDFFENGNNNLQVEYAIRQIFKANEAWGRKII
What are the official names of this protein?
Uncharacterized protein UU427 homolog.
Protein: LEUD_ZYMMO
Sequence: MKAVKIVEGRAYPLGESNIDTDIIIPAHYLKTTDRKGLAKGAFETIRAKEGNVFDNPEYKGAPILIAGDNFGCGSSREHAAWAIKEMGVEAVIAPRFSDIFSGNAFKNGLLTVVLPEADVERLLEVAKTDPITLDLENQVVTTPFQDRFHFDIDPFRKRCLLEGLDEIGLTLKDQDKISQYEDVLASDRPWV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: KMT5B_DANRE
Sequence: MGESKNMVLNGRRHGRKFSSNQPVSKSRLQNTQRSHLRQNKGSPSVRRCSRRCGGAPPEAERRHVPSSGMTAKELCEYDDLSTSLILDPYLGFQTHKMNTRFRPIKGRQRELREIIELFKKHDNLEKAFQALTSGDWTRHHFLNKTKSQEKLFKAHVFVYLRMFASDSGFEILSCNRYSSEQNGAKIVATKDWKRNDKIEHLVGCIAELSPSEERMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKVLRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSKPGLPVEAPVINSKYGLRETDKRLNRLKKLGESCRNSDSQSVSSNAEADSQEPTTVQTSLRKRTSQSCVKKHGEAKAVTRQTLSSTPSSTSSSKRSQANISSLPKRLKSKPTQTLSKGRRRCRGLWTKGSSRVSASGNLKESSRRDTDRRRSASKGSVARSSENNRSSSKGASPCKDSTLCPYRTRRSTRTSLGAQGAEGTEASNHPASPSIVLKSEPGEFIPVTLGHQMSTPSLDSSCPKKGTCPRRRRTVKQEDSYGESFVQEGVPDLRHAVRAADVADCGKVVLGLPDRHQHYNGSSKSSKALRRGKGKKKRQITRYDAQLILQNNSGIPKITLRRRRDSSSSKNEPRETSSSSSSKISIKFSKEHEKDRSSSYVAKLNNGFSHGPHSSSTKLKIQLKREEDPASLHRTYPEDVTLGIVQRDAADVLDHKAAAQVGQDMEVESMSSEDDDDDYFDNEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA
What is the function of this protein?
Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity.  In vitro also methylates unmodified 'Lys-20' (H4K20me0) of histone H4 and nucleosomes (By similarity).  H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression.  Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions.  KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).  Plays a role in myogenesis by regulating the expression of target genes, such as EID3.  Facilitates TP53BP1 foci formation upon DNA damage and proficient non-homologous end-joining (NHEJ)-directed DNA repair by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity).  May play a role in class switch reconbination by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase KMT5B, Lysine-specific methyltransferase 5B, Suppressor of variegation 4-20 homolog 1, Su(var)4-20 homolog 1, Suv4-20h1, [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B, [histone H4]-lysine20 N-methyltransferase KMT5B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with pericentric heterochromatin.
Protein: KAD_BURP6
Sequence: MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTPLGVEAKTYMDEGKLVPDSLIIGLVKERLKEADCANGYLFDGFPRTIAQADAMKEAGVAIDYVLEIDVPFSEIIERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLVQRDDDKEETVKKRLDVYEAQTKPLITYYGDWARRGAENGLKAPAYRKISGLGAVEEIRARVFDALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y788_ARCFU
Sequence: MGEDRRSLRVDYDDNFLRNNICSLKVSFIKQQGGAEGVKRLYADLGLALVALIWGSTFPVVKIALDSMSPFAFNTVRFFIACLFFLPFLKGWDFKDGFKIGIASFLGYTFQTVGLDYTTATNAGFITSTYVVLAPIISWLVYKDVFDKRDVSGVLLAFVGFYFLSGYSGFNIGDILMLFCALFFGAEIAMISHYSRLSNPTMLAFWQSFAIFILSAPFAVFTTTKFEINTTVILCLLITAFFATFVAKMLQNWLQSYTKSSDAAVILSLEGVFAHLFSVAVLAEILTPVQYFGAFLILLAVIIVSLRV
What are the official names of this protein?
Uncharacterized transporter AF_0788.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IFNG_MARMO
Sequence: MKYTSYILAFQLCIILGSSSCYSQDTVNKEIEDLKGYFNASNSNVSDGGSLFLDILDKWKEESDKKVIQSQIVSFYFKLFEHLKDNKIIQRSMDTIKGDLFAKFFNSSTNKLQDFLKVSQVQVNDLKIQRKAVSELKKVMNDLLPHSTLRKRKRSQSSIRGRRASK
What is the function of this protein?
Produced by lymphocytes activated by specific antigens or mitogens.  IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions.  It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHJ_OENBI
Sequence: MQGRLSAWLVKHGLVHRSLGFDYQGIETLQIKPEEWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIEYGVDQAEEVCIKVFAPRNNPRIPSVFWVWKSADFQERESYDMLGIRYDNHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: H4_DROOR
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.