PharMolix/UniProtQA huggingface dataset:
Protein: DHA2_CUPNH
Sequence: MNMAEIAQLGVSNPYKQQYENYIGGAWVPPAGGEYFESTTPITGKPFTRVPRSGQQDVDAALDAAHAAKAAWARTSTTERANILNRIADRIEANLKLLAVAESIDNGKPVRETTAADLPLAVDHFRYFAGCIRAQEGGISEIDADTIAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALAAGNCVVLKPAEQTPASILVLMEVIGDLLPPGVVNVINGFGLEAGKPLASSPRISKVAFTGETTTGRLIMQYASQNLIPVTLELGGKSPNIFFEDVLAADDAFFDKALEGFAMFALNQGEVCTCPSRALIQESIYDRFMERALKRVAAIRQGHPLDTGTMIGAQASAEQLEKILSYIDLGRKEGAQCLTGGERNVLDGDLAGGYYVKPTVFAGHNKMRIFQEEIFGPVVSVTTFKDEEEALAIANDTLYGLGAGVWTRDGARAFRMGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRENHRMMLDHYQQTKNLLVSYSPNALGFF
What is the function of this protein?
Involved in the catabolism of acetoin and ethanol.
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase II, ACDH-II.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ASTA_YERE8
Sequence: MMRVRPVERRDLADILELAGKTGVGMTSLPQNEQHLAARIERALNTWQGSLAVGEQGYLFVLEDTEREKVVGVSAIEVAVGMNDPWYNFRVGTLVHASKTLNVYKSVPTLFLSNDHTGYSELCTLFLDPEYRKDKNGPFLSKVRFLFIAAFRQHFSRKLIAEMRGYTDEQGRSPFWENVGRHFFSIEFAKADYLSGTGQKAFIAELMPKHPLYVDFLAEEARAVIGQVHPHTAPARAVLETEGLQYQGYVDIFDGGPTLEANTDEVRAVRDSSQRKVVIDDIDIDPSGSAYLVANDRYQEFRSILINTHLSDEFLHLTPDNAAALGVVAGDVVRIISLFAPETKK
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: RS4_AZOSB
Sequence: MARNLDPKCRQCRREGEKLFLKGEKCFTDKCAIERRAYAPGQHGQRSGQRLSGYGVQLREKQKIRRLYGVLERQFRKVYAEADRRRGQTGENLLQLLEGRLDSVAYRMGFGASRAEARQVVRHNGVLVNGKRVNIPSYTVRPGDVIELAEGTKGHLRVKAALEAAESRGFPEWIEVDAKAGKGVFKAYPQRSELSATINEGLVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: XYL2_PIG
Sequence: XXKLVESGXXLVQPGGSLRLSKXYTENVNHPATTTXYKXQPMTPDFTEXQTHEGTHQDVFDQPNLXXWKGNTLPEGYEPAKXGEXGTQDANPKXXQDGDEXTXTGXXQXDKIGRYNLXPTIFFEATPPKANENQ
What are the official names of this protein?
D-xylulose reductase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: INSF6_ECOLI
Sequence: MKYVFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQFRQHCDSVVLAAFTRSKQRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKFSPVSYRAHGLPVSENLLEQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSPRMTAQLACDALQMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFHSLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsF for insertion sequence IS3fA.
What is the protein family that this protein belongs to?
Belongs to the transposase IS3/IS150/IS904 family.
Protein: Y655_THEP3
Sequence: MPRPPKCRWVRSEPNVTHFKPVGVPMSMLDEVILTVEELEAIRLKDLEGLEQEECAEMMKVSRPTFFRIINSARQKVADALVNGKAIRVEGGNYRVYDEDQRGHRGMRHRHGQWGRED
What are the official names of this protein?
UPF0251 protein Teth39_0655.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: GNMT_MOUSE
Sequence: MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVMSVDASDKMLKYALKERWNRRKEPSFDNWVIEEANWLTLDKDVLSGDGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGTGRDGSPGFSKFRLSYYPHCLASFTELVRAAFGGRCQHSVLGDFKPYKPGQAYVPCYFIHVLKKTD
What is the function of this protein?
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate (PubMed:15340920).  Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine (PubMed:16779654).
What are the official names of this protein?
Glycine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_XANP2
Sequence: MNPQDIKTALGSGLLSFPVTHFHADGRFNAESYKQHIEWLAGYDAPVLFAAGGTGEFFSLAPSEIPGIVSAAKEAAGKTAIVAGCGFGSVVGVEIAKAAEKAGADGLLLLPHYLIDAPQEGLYALVKQICDAVGIGVMVYNRDNSVLGVETLARLCDACPNLVGFKDGTGQIGLVRQITATMGDRLIYLGGMPTAELFAEAYLGAGFTTYSSAVFNFVPGLAVEFYRALRAGDRPTCERLLRDFFYPFMAIRNRRKGYAVAAIKAGVRLQGFAAGPVRAPLDDLTIEEEAMLDALIGTWKR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: NUOD_BURPS
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLTGPMIRGSGIAWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRKNPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHFR_XENLA
Sequence: MEGLDEKKPWGKLSRLLGAETDSSSELFLYKKEWTIGRKKACDLSFPGNKLVSGEHCKITVNEESGEVSLEDTSTNGTVINKLKVIRKQTYPLKNGDVIYVVYRKNEPEQNVAYLYKSLNQGQDSLHDPADTSGSEEAETQTLSSQDDQLSYEEPQPSTSTSSLFSTPTTSAIPGVQLESAEKSGESLGGHSSTSDASPAIRASIPKSNLSTQEQGSLGPPKKRIRTEDHWTTNKNFVPASCPIGASDESKTPSMKPDKMEETLTCIICQELLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPEKCRSEEDRCSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYTVCRQCPGFVRHSMQPPPYPPPSDTETSRTQGDAPSTSTNFPTATQEYVCPSHGSHVICTCCFQPMPDRRAEREHNSHVAPQQCTICLEPFCHMYWGCNRMGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLASRGLTWKDMLNESLAAVQRGVFMLPDYRINGTTVLCYFCGLRNFRILTYQYRQNIPASELPVTVTSRPNCYWGRNCRTQVKAHHAMKFNHICEQTRFKN
What is the function of this protein?
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons.  Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus.  Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome.  May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating ubc13-mms2 (ube2n-ube2v2) heterodimer.  Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.
What are the official names of this protein?
E3 ubiquitin-protein ligase CHFR, Checkpoint with forkhead and RING finger domains protein, RING-type E3 ubiquitin transferase CHFR.
What is the protein family that this protein belongs to?
Belongs to the CHFR family.
Protein: BM01_DROME
Sequence: MKFFSVVTVFVLGLLAVANAVPLSPDPGNVIINGDCRVCNVHGGK
What is the function of this protein?
Secreted immune-induced peptide induced by Toll signaling (PubMed:9736738, PubMed:25915418, PubMed:29920489).  Has a role in resistance to bacterial and fungal infections (PubMed:9736738, PubMed:25915418, PubMed:29920489).  Has no activity against the fungus C. glabrata in vitro (PubMed:29920489).
What are the official names of this protein?
Bomanin Short 1, Bomanin-1, Immune-induced peptide 1, DIM-1.
What is the protein family that this protein belongs to?
Belongs to the bomanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NARL_SHIFL
Sequence: MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
What is the function of this protein?
This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted by either the NarX or NarQ proteins.
What are the official names of this protein?
Nitrate/nitrite response regulator protein NarL.
Protein: ACCA_XANCP
Sequence: MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVDAEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTMCDEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKSKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIARNLMEMAELKVPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAKAKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKVPVDALMQQRYERLRSYGAYEGH
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ACIBS
Sequence: MARVTVEDCLDHVDNRFELVLVASKRARQLARQGMEPTVEWDNDKPTVVALREIAVGHVTKEILKQREQDYQTSSLDLALSTNSLNLEGFSF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CSMA_PROA2
Sequence: MSGGGVFTDILAAAGRIFEVMVEGHWETVGMLFDSLGKGTMRINRNAYGNLGGGGGSLRGSSPEVSGFAVPTKAVESKFAK
What is the function of this protein?
Component of the photosynthetic apparatus.  The light harvesting B740 complex binds bacteriochlorophyll c.
What are the official names of this protein?
Bacteriochlorophyll c-binding protein, BChl c-binding, Chlorosome protein A.
What is the protein family that this protein belongs to?
Belongs to the BChl C/E-binding protein family.
What are the subcellular locations of this protein?
Chlorosome, chlorosome envelope.
Protein: SG1C2_HUMAN
Sequence: MKGSRALLLVALTLFCICRMATGEDNDEFFMDFLQTLLVGTPEELYEGTLGKYNVNEDAKAAMTELKSCRDGLQPMHKAELVKLLVQVLGSQDGA
What are the official names of this protein?
Secretoglobin family 1C member 2.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HLDD_SYNC1
Sequence: MLIVTGGAGFIGSNIVQALNARGREDILVVDDLTDGTKFANIADARICDYLDKDEFLRRIASGDSFGDRIEAIIHQGACSTTTEWDGRYMMENNYAYSKTLLHYCLERRIPFLYASSAATYGGGQVFCEEPQYERPLNVYGYSKALFDQYVRRVLPTADSQVAGFRYFNVYGPREQHKGSMASVAFHLRNQLLKDGSVNLFEGCDGYGDGEQRRDFIYVGDVVDVNLWFLDHPEVSGIYNVGTGRSQTFNDVAHAVLKAHEGGELQYVPFPEHLKGRYQSFTEADLTRLRGAGFDGSFLTVEEGVARYMEWLQQN
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: Y118_PSYA2
Sequence: MKVNQDTHNAQPKLIDSNESVGDRLNILVVSGRSGSGKTSVLNILEDLGFYSIDNLPLSLVPEAVQKLVCDSGIKRIALGVDIRTPRADLSNFAAIHDSLKQAYGEEAVTVMYVTAQEETLVARFNATRRIHPLMVLDTKGVENTAYNLPAAIEKEIQLLQPICKYADIKIDTSMLNIHQLKERLRDYVGVDNQIVINLLSFGFKYGSPIDADFVFDVRILPNPHWNPTLRAATGLDAEVGEFFADYPEVTEMTGDIATFLNRWLPDFLHNNRHTVTVAIGCTGGKHRSVFITKHLQDSLQNSLPEGLTVTAKHREKHRW
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Psyc_0118.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CPXB_PRIM2
Sequence: MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
What is the function of this protein?
Functions as a fatty acid monooxygenase (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028).  Catalyzes hydroxylation of fatty acids at omega-1, omega-2 and omega-3 positions (PubMed:1727637, PubMed:21875028).  Shows activity toward medium and long-chain fatty acids, with optimum chain lengths of 12, 14 and 16 carbons (lauric, myristic, and palmitic acids).  Able to metabolize some of these primary metabolites to secondary and tertiary products (PubMed:1727637).  Marginal activity towards short chain lengths of 8-10 carbons (PubMed:1727637, PubMed:18619466).  Hydroxylates highly branched fatty acids, which play an essential role in membrane fluidity regulation (PubMed:16566047).  Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain (PubMed:3106359, PubMed:1727637, PubMed:16566047, PubMed:7578081, PubMed:11695892, PubMed:14653735, PubMed:16403573, PubMed:18004886, PubMed:17077084, PubMed:17868686, PubMed:18298086, PubMed:18619466, PubMed:18721129, PubMed:19492389, PubMed:20180779, PubMed:21110374, PubMed:21875028).  Involved in inactivation of quorum sensing signals of other competing bacteria by oxidazing efficiently acyl homoserine lactones (AHLs), molecules involved in quorum sensing signaling pathways, and their lactonolysis products acyl homoserines (AHs) (PubMed:18020460).
What are the official names of this protein?
Bifunctional cytochrome P450/NADPH--P450 reductase, Cytochrome P450(BM-3), Cytochrome P450BM-3, Fatty acid monooxygenase, Flavocytochrome P450 BM3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGPS1_CHICK
Sequence: MAAAGGAALWRRLAAWLPRGPPGLAALLGRLSDRLSRGRDRRSRRSSWLLLAPLLTPPVPVITAMPCSLCPEGAHRFQWIRNLVPEFGISSSHVKVLSSPAEFYELLKVQIKTAKQRVVMASLYLGTGLLEQELVNCLEETLEKSLQANESPNLRVSILLDYTRGSRGRKNSRTMLIPLLQRFPEQVRVSLFHTPNLRGLLKLLIPERFNETIGLQHIKVYLFDDNVILSGANLSDLYFTNRQDRYVLLQDSPEIADFFTELVDAIGDVSLQLQQDDTVQMMEGMVHPYQGDKVRYCEIANQRVMEVIDSARTRQELLHAKTFHSSQQGSSMLPQHDSEASEGLKPEPDTWIYPLIQMKPFGIQIDEMVTETLLTEAERDAKIYLTTGYFNLTQAYMDLILGTRAEYRILLASPEVNGFFGAKGVAGAIPSAYVYIEHQFYNEVCCLHQQERVQLQEYSRAGWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQVAIVTENKALQQQLHQEQEQLYLCSGVVSSSTFEQPSRHVKLWVKLVTPLIKNFF
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, Phosphatidylglycerophosphate synthase 1, PGP synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTSW_PSEFS
Sequence: MSIDFRNIIKPYPSPIITGRGIDLDFPMLAGCLALLGLGLVMITSASSEVAAVQSGNTLYMMIRHLVYLVIGLGACIVTMMIPIATWQRLGWLMLIGAFGLLIMVILPGIGREVNGSMRWIGFGAFNVQPSEIAKVFVVIYLAGYLVRRQKEVRESWMGFFKPFIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFTLMVVLAVAAVTVLVQAQPYRMARLITFTDPWSDQFGSGYQLTQALIAFGRGEWLGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLCTVALFVFVCVRGMYIGMWAEKAKQYFAAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCACLGLLLRIEWESRTHLGSEEMEFSESDFAEEPTHGR
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: ISPF_BURO0
Sequence: MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: FLPA_SULIM
Sequence: MSEVVTVKQTNMENIYECEFNDGSFRLCTRNLVSGFNVYGERLIKYEGVEYREWNAFRSKLAGAILKGLKTNPIRKGTKVLYLGAASGTTISHVSDIIELNGKAYGVEFSPRVVRELLLVAQRRPNIFPLLADARFPQSYKSVVENVDVLYVDIAQPDQTDIAIYNARFFLKVNGYMLLVIKARSIDVTKDPKEIYKAEVEKLENSNFETIQIINLDPYDKDHAIVLSRYKG
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: CNIH3_RAT
Sequence: MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCVMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS
What is the function of this protein?
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
What are the official names of this protein?
Protein cornichon homolog 3, CNIH-3, Cornichon family AMPA receptor auxiliary protein 3.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells).
Protein: KCY_SACS2
Sequence: MIIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQSMGLDIINLNRVAESNFDIDKMVDKKIHEYVLRERNLIVESHIAGWIFREYTDVAIYLWAPLKIRANRIAIRDKISYVEAVSQIIRREYMHYKRFNKFYGIDINDLSVFDLVINTSNIDINNIVKLILDYLSSVSHNSQPLKEKNINDK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL16_PANTR
Sequence: MDYSFDTTAEDPWVRISDCIKNLFSPIMSESHGHMPLQPNASLNEEDGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGKHEEGRFSGLLGRGAAPTLVPQQPEQVLSSGSPAASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQTEESQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS
What is the function of this protein?
Pro-interleukin-16 is involved in cell cycle progression in T-cells.  Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene.  May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity).
What are the official names of this protein?
Pro-interleukin-16.
What are the subcellular locations of this protein?
[Interleukin-16]: Secreted. SUBCELLULAR LOCATION: [Pro-interleukin-16]: Cytoplasm. Nucleus.
Protein: GL121_ORYSJ
Sequence: MASSNFFLPTALIALVATQAMAFDPSPLQDFCVADRNSPVRVNGFPCKDAKDVNVDDFFLEANLDKPMDTTKSKAGSNVTLINVMKLTGLNTLGISMARIDYAPKGQNPPHTHPRATEILTVFEGTLYVGFVTSNQANGENKLFTKTLNKGDVFVFPQGLIHFQFNPSYDKPAVAIAALSSQNPGAITIANAVFGSNPPISDDVLAKAFQVDKKAVDWLQAQFWENNHN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 12-1.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.