PharMolix/UniProtQA huggingface dataset:
Protein: ACUK_ASPOR
Sequence: MTVDAQDSTPAPPADRRGAELETGGVGEQSEQPKNKSNGDGNAPAETGQKPNPKDPSRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLQDACHDGVRKKAKYLHDAPDGALMPGIGGNFYNNTMRSNLPLSRNGANAVNATTQPSSSPNFYPTPQSNSYSVYQENTMNQNSFTSQSPVSPTFTLKANPAARNNSLSSQVNQQPPSTGVSGATNPSQNPFAGPFFDPSDPALFNFDLSSMNFENRYGALEFGMLGHMATGAGDSPSDSATQRGSMGRSGSAQFSGTPITGAAAFGESPGGQQPFIFGDPLLNEWSSGQPTGQTHVNVGGVYPQSGQGSVIPGHLTKADAPHAFAIESGPGSFASPNATTSPQITTGFDDATFSSAVTAKSNGLSANGPRPTITTPSLKHQNLQVGVRRRQRNPSSIYENVKEPYAYTNRFHNLTAFIQRRFSPQKTLQIAKALASIRPSFIATTKTLNRDDLIFMEKCFQRTLFEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWKKDVLLGKEPNLNVNTGGSVPGSGTSSRSFTPRGSVAESTPGRPQPVFLAELLDDDSVVEFYEDFARLAFGDSRGSVMTTCKLLKYKTKEDMENQSDDNQRWNSHLRKGGIASEAGMNQLGFKDGKIECAYCWTVKRDVFDIPMLIVMNASSTNLR
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis acuK.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUP49_YEAST
Sequence: MFGLNKASSTPAGGLFGQASGASTGNANTGFSFGGTQTGQNTGPSTGGLFGAKPAGSTGGLGASFGQQQQQSQTNAFGGSATTGGGLFGNKPNNTANTGGGLFGANSNSNSGSLFGSNNAQTSRGLFGNNNTNNINNSSSGMNNASAGLFGSKPAGGTSLFGNTSTSSAPAQNQGMFGAKPAGTSLFGNNAGNTTTGGGLFGSKPTGATSLFGSSNNNNNNNNSNNIMSASGGLFGNQQQQLQQQPQMQCALQNLSQLPITPMTRISELPPQIRQEIEQLDQYIQKQVQISHHLKADTIDHDELIDSIPRDVAYLLKSESATSQYLKQDLKKISSFKSLIDEDLLDTQTFSVLLQQLLTPGSKISSNDLDKFFQKKIHLYEKKLEDYCRILSDIETAVNGIDTDLFGAPNNPNSTAITADLGSSEAENLLQLKTGLAAIVSTVIEEFTLFMDIAERIAVLHQKTKTLASLSI
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  NUP49 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport.
What are the official names of this protein?
Nucleoporin NUP49/NSP49, Nuclear pore protein NUP49/NSP49.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin GLFG family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: PLSY_SHEB2
Sequence: MSPLTQTLLMILAAYLAGSISSAVLVCRMRGLPDPRLQGSGNPGATNVLRIGGASSAAMVLFFDMLKGAVPSYLAYLMGIDAVSLGLIAIAACLGHIYPVFFGFKGGKGVATAFGAMAPIGDDLAICLMASWVVLLLISRYSSLAAILTALLAPLYTWWLDDRFTIPVAMLSTLIIIRHKDNIQRLLKGEESKVSRKKRPKKS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DLDH_ACHLA
Sequence: MSKEYEIIIVGGGPGGYVAAIKAAQYGAKVALVEKEVVGGICLNHGCIPTKTFLKSAKVFNTVKKSMDFGVSTSGEVGFDWSKIVSRKDGVVKQLTNGVAFLLKKNGVDVYNGFGDIKSANEVVVNGESLKTKNVIIATGSSAVVPPIPGVKEAYEKGIVVTSRELLNVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAYAKTLKRDGIEILTKAEVKKVDDHKVTYSLDGKETTIEGDLILMSVGTRANSKGLEHLGLEMDRANIKTNEYLQTNVPGVYAIGDVNGKFMLAHVAEHEGITAVQHILKIGHAKMNY
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate complex.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRG8_ASHGO
Sequence: MPRSVPDMSELLVKGVKHVYGRKMRKTRPTLPNVESPLVTHFHRWAGKRIRLSFLAAELGTREGQHILPDWNLRGNLFAGLLAAPMRWDRLGNLRVPKSFLMQTKARALEAPSDGKLVKIISVVEERGPGSSSYVPQSKAALQRAKQAMFVPVALQQSDMRYFSSEEIAVDKDTLLAEYSAQLISKVKEGLEVLLSMSGTSHERVELEDWDVVVTYDPDNANDIELRKCKGIPGDPVVIILNMGCLKCTELEELVNLRLRNHEYGLVLKVLKNERLLKFMYRLITFSR
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG8 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSF1_CAEEL
Sequence: MSSGDQNRGGVADKALQLVLEMKRNPDVLPPYNTELVRQCYQKIDELFQKNAAVVEKIRAGLPHDSTLLQPRLAAMCHIRRCMMAYVNERKNRIRSFRWKYGGALPASVRNALCDAEIQFFNEYSSTLARFQSNLGEGGVNLLLHSAPPKSLFVQVRALEDYGEFETSDGTQVQLSKDSLHSLPRQDCEMLIRQGVLELVH
What is the function of this protein?
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks.  GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
Probable DNA replication complex GINS protein PSF1, GINS complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LOLA_VIBCH
Sequence: MNKWLALLFCSFSAIAAPKDTLSERLAMSEGFSATFNQQVLSPEGKVILTGNGKVDIARPSLFRWETETPDENLLVSDGTTLWHFDPFVEQVTLYRAEEALEQTPFVLLTRNKASDWDAYHVEEKGDVFTLTPTALDSNQGRFQITISEKGVVQGFKVIEQDGQQSEFTFSKVKQQKPNASVFNYKVPKGVEVDDQRN
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CEBP2_CAEEL
Sequence: MSGNRKRNTSEPREDDEDDYSTKRKRNNEAVNRTRQKKRQEENDTAEKVDELKKENETLERKVEQLQKELSFLKEMFMAYAKNDGNDGPPPPPPPSSSAV
What is the function of this protein?
Transcription factor that binds to the promoter and the enhancer regions of target genes (By similarity).  Regulates expression of genes involved in fat metabolism, including ech-1. 1 and fat-5 (PubMed:26505800).  Has a protective role in response to infection by the Gram-negative bacterium P. aeruginosa (PubMed:26876169, PubMed:28662060, PubMed:34804026).  Required for the activation of infection response gene irg-1 following P. aeruginosa infection (PubMed:26876169).  Required to prevent P. aeruginosa ToxA-mediated lethality (PubMed:26876169).  May also function in concert with transcription factor zip-11 to mediate immune responses, independently of the pmk-1/p38 MAPK pathway (PubMed:34804026).  May act together with the bZIP transcription factor, zip-2 (PubMed:26876169).
What are the official names of this protein?
CCAAT/enhancer-binding protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_DESAL
Sequence: MANHKSALKRAKQNTIKQMRNRSYKTRLRNMVKKVNQAVEAQSVDEAKTILVETQSIIDKCASKGVIHKNTASRKISRLAKKVEALAG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CPSF5_MOUSE
Sequence: MSVVPPNRSQTGWPRGVNQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7.  Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing.  The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA (By similarity).  Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function(PubMed:29249356).  Binds to chromatin (PubMed:18032416).  Binds to, but does not hydrolyze mono- and di-adenosine nucleotides (By similarity).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 5, Nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21, Nudix hydrolase 21.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. CPSF5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a transcription- and XPO1/CRM1-independent manner, most probably in complex with the cleavage factor Im complex (CFIm). In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles.
Protein: PTMCB_STRMU
Sequence: MERKSSLKVRVQKLGTSLSNMVMPNIGAFIAWGVAASLFIATGYLPNKALDTNVVGPMLKYVLPLLIGYTGGYNIHKQRGGVIGAIASFGAIAGSTVTMFIGAMIMGPLSAWILKKFDEKVQPKIRTGFEMLVNNFSLGLIGFALMVLAFFVIGPVVAQLTEWVGIGVEAIVKVHLLPLANLIIEPAKILFLNNALNHGIFTPLGTEQVAKVGKSVLFLLEANPGPGLGVLIAYAMFGKGSAKSSSWGAMIIHFFGGIHEIYFPYVMMKPAMFLAVIAGGLTGTFTFQTLGAGLTAPASPGSIIAIMGMSPKGWGPHLVVLAGVFAAAVASFLVASIILKSDNSDDDSLETAQAVTQAAKAESKGQAVTEPNLHSDITTDNIHQIIFACDAGMGSSAMGASILRDKVKKAGLDISVSNQAISNLQDTANTLIVTQEELADRAGQKTPRAVHVAVDNFLATSKYDDIIASLTNGKASGSENAAHSTQADSAEIDLNQIDAVVFAYGIAKGSATMGQETLRSIFKQNNVKIPVSTASYAHLSDYNAKNILLVTTIAQQGQAQQAAPNAQILVVDSLVTTPEYDKLVARMHK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_STRA3
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDLDKAIELLREKGMAKAAKKADRVAAEGLTGVYVDGNVAAVIEVNAETDFVAKNDQFVTLVNETAKVIAEGRPSNNEEALALTMPSGETLEQAFVTATATIGEKISFRRFALVEKTDEQHFGAYQHNGGRIGVITVVEGGDDALAKQVSMHVAAMKPTVLSYTELDAQFVHDELAQLNHKIEQDNESRAMVNKPALPFLKYGSKAQLTDEVIAQAEEDIKAELAAEGKPEKIWDKIVPGKMDRFMLDNTKVDQEYTLLAQVYIMDDSKTVEAYLESVNAKAVAFVRFEVGEGIEKASNDFEAEVAATMAAALEK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR67A_DROME
Sequence: MDNVAEMPEEKYVEVDDFLRLAVKFYNTLGIDPYETGRKRTIWFQIYFALNMFNMVFSFYAEVATLVDRLRDNENFLESCILLSYVSFVVMGLSKIGAVMKKKPKMTALVRQLETCFPSPSAKVQEEYAVKSWLKRCHIYTKGFGGLFMIMYFAHALIPLFIYFIQRVLLHYPDAKQIMPFYQLEPWEFRDSWLFYPSYFHQSSAGYTATCGSIAGDLMIFAVVLQVIMHYERLAKVLREFKIQAHNAPNGAKEDIRKLQSLVANHIDILRLTDLMNEVFGIPLLLNFIASALLVCLVGVQLTIALSPEYFCKQMLFLISVLLEVYLLCSFSQRLIDASENVGHAAYDMDWLGSDKRFKKILIFISMRSQKPVCLKATVVLDLSMPTMSIFLGMSYKFFCAVRTMYQ
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  Forms a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to benzaldehyde and acetophenone.
What are the official names of this protein?
Odorant receptor 67a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or49a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FAX2_ARATH
Sequence: MADLILSSSSAQSSLLHVRPNHYLLNTSTASPIRSVRFQNSNGFHPLAFASGHRRLPLGAVVPSDSTKTITSTITANCVDSGVKAVEVEPTIDYGGGGGIGGDKFGGGGGGGDGNDDGGEDDKEESDGKKSTPLSMSQKLTLGYAFLVGVGGLMGYLKSGSQKSLLAGGLSAAVLLYVFSQLPTKPVLASTVGVVMAGALMYVMGTRYMRSKKIFPAGVVSIMSFIMTGGYIHGIMRSLH
What is the function of this protein?
May be involved in free fatty acids export from the plastids.
What are the official names of this protein?
Protein FATTY ACID EXPORT 2, chloroplastic, At-FAX2.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: MURG_BACFN
Sequence: MNKENNKEGQGDALRVIISGGGTGGHIFPAVSIANAIKELRPDAQILFVGAEGRMEMQRVPDAGYQIIGLPVAGFDRKHLWKNVAVLLKLVRSQWKARNIIRQFRPQVAVGVGGYASGPTLKMAGMMGVPTLIQEQNSYAGVTNKLLAQKARRICVAYDGMEKFFPANKIIMTGNPVRQNLLAEKPEREQAIRSFGLNPEKKTILILGGSLGARTINNTLIAGLQLIRRTTDVQFIWQTGKIYHQQVTEAVKAAGEIPNLFVTDFIKDMAAAYAAADLVISRAGAGSISEFCLLNKPVILVPSPNVAEDHQTKNALALVNKQAAIYVKDAEAENKLLPVALETIANAEKLSELSENIAHLALPDSAVVIAKEVIKLAQQS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSCA_BORPE
Sequence: MALLQISEPGDSPAPHQRKLAVGIDLGTTNSLVAAVRSSVPEVLADAQGQVLLPSAVRYLDGGAVRIGREALLEQARDPLNTIVSVKRFMGRSAADAAASGAPYEFVDAPGMVRLRTVQGDLSPVEVSAQILAVLRQRAEDVLGDDLVGAVITVPAYFDDAQRQATRDAARLAGLNVLRLLNEPTAAAIAYGLDQAAEGIYAVYDLGGGTFDISILRLTQGVFEVIATGGDTALGGDDFDSAIVAHACAGEDVAALPVADRRALLVAARAAREALTDQAQAPFEVTLRDGRAIQATLTRAQFEQLAEPLVGRTLDSARRALRDAGLAVGDVRGVVMVGGATRMPVVRQQVGALFGTEPLTNLDPDQVVALGAALQANLLAGNRALGEDWLLLDVIPLSLGLETMGGLVERIIPRNSTIPVARAQEFTTFKDGQTAMSVHVVQGERDLVSDCRSLARFELRGIPPMVAGAARIRVTFQVDADGLLSVTAREQSTGVEAAVAVKPSYGLSDDEIARMLADSVTQADSDARARMLREQQVEARQLVESVGAALAADGDLLDPAERATVDQRLQAAAQAQSLDDVEAVRAAVQALSDATEEFAARRMDRSIRSALAGRKLDELA
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LEUC_NOCFA
Sequence: MADRPRTLAEKVWEEHVVARGEGEGASREPDLIYIDLHLVHEVTSPQAFDGLRAAGRPVRRPDLTIATEDHNVPTVDIDKPIADPISRTQVETLRRNCAEFGIRLHPMGDLEQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLSLRPFKTMAINIDGQLPPGVTSKDVILAVIAQIGTGGGQGYVLEYRGEAVRAMSMEARMTMCNMSIEAGARAGMIAPDEVTYEFLKGRPHAPKGADWDAAVAAWDALRTDEGAVFDAEVHIDASSLSPFVTWGTNPGQGAPLSATVPDPADFADETAREAAAKALRYMDLTPGTPLREVAVDTVFVGSCTNGRIEDLRAAAEILKGRRVAEGVRMLVVPGSMRVRAQAEKEGLGEIFTAAGAEWRQAGCSMCLGMNPDQLEPGQRCASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPADLD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DNLJ_SULSY
Sequence: MYTDERQKELIKLTYEFLKLDAKKLTKEEAKKIVEDLREVIRFHDWRYYVLAQPVISDYEYDKLFKLLKDIEGKYPELITPDSPTQRVPSEITKVFPQVKHLTPMLSLDNSYNEADLRDFDRRVRELTGLDKVEYSVEPKFDGAGISLIYEKDLFVRGATRGDGEVGEEITNNLKVIKTIPLSAKFSQYGIDKVEIRGEVLIRKDLFKKMNEERLEEGLPLFANPRNAAAGSIRLQDPSEVAKRNLEAFVYQITYAEKDGKNLLGTVLKKHSDNIKMLHELGFKTPYPVMKVCIGIEEVIQYCEEWQRKRDAYPYEIDGMVIKVNDISLYDKLGFTSHHPRWAIAFKFKARQATTKIINVVFQVGRTGAITPVAKLEPVEIGGVIVSSVSLINEDFIREKDIRIGDTVLVERAGDVIPYVVMVIKEARTGNEKPIEFPKTCPSCGSPIVKPPGEAVYRCVNINCPAQVIERLIHFASKDAMDIKGLSEATIRKFYNLKLVRTIPDIYRLDYNLIKNIPGFGPKSVENLKNAIEESKKRPLYRLIYGLGIRYVGEVTAKTLASAVRCIDDLKNFTITDLMKLPDIGYKVASEIYNFFHNQENLKMIEELRELRVKTCHEEEEKKGKLAGLNFVFTGTLKCCSREKAKEIVESLGGNVLDTVSKKVHYLVVGEEPGSKLQKAQKLGTVKIINEEEFLKLIGGENTE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CCME_RHILO
Sequence: MTRKQKRLSVIVGGLAFLGAATGLTFYALGQKASYFYMPADLTTASVQPGQRIRLGGLVEKGTIQRGQGATVAFSVTDTHKSVKVTYTGILPDLFREEQGVITEGSFGPDGVFVADSVLAKHDERYMPKEVADGLKAKGVWQESKSE
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: HIR2_ASHGO
Sequence: MKLLKYPRQLHDGQLLAGCVVGGLLVVVGRDRISAYDCGKLQAAARGELAVREVSAEVELQVEVGEDALRYVAGGEGELVVAGDRQIWAAGADWRSAGRGTRFLTVAQLAGGACVTDVKADGAGLVFVSVSGKDEVWLYATGAWERVGVVTLAAKPVTLVVDPLGELLTVVLQNRSVAVYQYNRQGAVRMHQQLPQYVQTNPLRYSITMSPQGDLLPLVNSIKNGLPSAQLLDRTAGFSVQSTLVGYVDKCKILRFSPRLYEKPNKDKPPTQYNLLASSGNEDGSVIVWNTKRTKPLLNAAKVTDTFINDVQWSRDGTGLFAISNDGYLFIFAFHEVELGRLLDDAELEKLRQSVPRLEPLPPPTPKSLAKSEAKPQQDTKPDAKSSANSVSAKTGKKKIAPTVITSTSMEFNEPSYTVPKDLKRRPKQETQTNGTTTKRPKRDVEPMDFLDTNLLIPNISFSKARLATPKVRMNFQYCNTLQQNLVMEVKNGTGSEQKPTSITLTLKDKEKDMVLFQDFTPRFVTICTCGHSFWACCTEEGIVYVYSNTGKKLLPPMIMGVPVSFLEGCGDYLLCVTSMGQLFCWNVKEGKLKFPVNTIYPLLNPSIRYSDDVLTRAENITMCTTTENGIPLVTLSNGDGYMFDPDMEIWLLINDSWWAYGSQYWDFTNTSHAGSSAAAGNDKEDKKNKYWNADAEYLIEEVKKNKKSVVNYLESKTNDEMTRKGLIRNLQRFAKTILMKEGFENLEDIVTLSHLENRLLVALKLNETNEFTKLLKVYCISLAEMGFKNRLDDVLSWLYNDGEYKVGTIANEKREELLKQILVACADIRQVQRVTTSYASALGLLDVSL
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_STAA9
Sequence: MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLIKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFKLPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_MICLC
Sequence: MSPLRIGTRGSALATTQTSHVAEALTARSGLAHELVVIRTEGDVTTGSLASLGGTGVFASALRAAVLDGVVDAAVHSLKDLPAAQPETLEIAAVPARADLRDALCARDGLTLATLPEGARVGTGSPRRVAQLKALRPDLELVDIRGNVQTRLARVPGLEQHDDHAPAAVGSPRGDLDAVILACAGLDRLGLDHVITERIDPEVMVPAPGQGALAMEIRAEDESFLGRALLDPEAPVGRLHAALELVDDRDTHVAVTAERALLRRLEAGCAAPIGAVARVGDGEAGAPRIEMTAMVAALDGSRVLRRTSSVQLDPVPADVVGDPAAADEWLEDTLFVAAEALGVHVAEQFVAEGADLLPGTVRGVDRGDGAPRPDDPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: Y2401_SYNC1
Sequence: MSLLFLDTFAGISGDMFLGLLVDLGVPLPSIQEGLDRLPVTGYQLHQQRTERQHVAACKIIVEHEEQHHHRTWRDIDRMLAESSLKPTVVDLARRIFRRIGEAEAKIHGRALDEVHFHEVGAIDSIVDIVGAAVGLDYLHPDRIVCAPLPLTRGTVHCAHGSFPLPAPATLEILRGLPTVGDTAEVELVTPTGAAIAAETAEFGDLPAMTLERVGYGAGDRQLSDRPNLLRGLLGTADDPWEGETDRITILECHLDDANPEWLGALMEHLLEEGALDVAFAPLQMKKNRPGVHLTVLAPQDKTVALARRILRESTAGGLRYQEATRFKLRRQIERLTTPLGEVHIKLFYEGDKLLRLAPEFDSCQKLAQSSGLPLPEIYRLAEQTAYDFFRKKG
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: RS15_THESQ
Sequence: MVSLDPEKKNEIIKEFQIHENDTGSVEVQIALLTARIKHLTEHLRKHPKDFHSRRGLMKMIGRRRKMLKYLRHKKPEVYRELIAKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SPH22_ARATH
Sequence: MKYFTIFFIFFSLCMFGHVSGAGIRIVNELKNKKTLWMRCYSKNDVLGPTIIPNGGQFTDYFFHNLFGTTRFMCTLKQGPGFSHSQSFRAFKNSGLWDWRAREDGIYLRRIYKTKFDDDTDNLHKEQSWI
What are the official names of this protein?
S-protein homolog 22.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.