PharMolix/UniProtQA huggingface dataset:
Protein: AKTP1_DROVI
Sequence: MTLDVDAQKKDEKLLLSTIQQEYKILAEYKMIESEKVSGIYVIPSYANSLQWFGVFFGRQGFYENSVFRFSILLPDGFPDDKAVPAIIFQHNVVHPLVCPYTNSLDISHAFPEWRCGEDHLWQVLKYIQAIFADPLDSIRSVANIQELSNPEASKLLNTNRDAYAALVQESIVESKSRVYDTPPTEDPHYIVFEKFQANVHGPVLDQIRKSRNTIVPAESGVGGAATGLSWVKVKEGDFKPLSIE
What are the official names of this protein?
Protein crossbronx.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: LDH_DESRM
Sequence: MKLRKGAKISIVGTGLVGASAAFAIMASGLASDLVLIDINKAKAEGEAMDLGDAAAFVKPLDVYAGSFEDCKDSDIIVFTAGANQKPGETRLDLVYKNVNILKESLPQLLKYCPYAIYLIVANPVDVLTHVALKISGLPSNQVFGSGTVLDTSRFRAELAEYCNVDPRNVHAYILGEHGDSEVAIWSTADVSGIPLKEFFQLRGIPPISREKVVKRVRNAAYEIIQLKGATYYAIAFTIKRICETVLRDENSILTVSGIVNDLYGIQDCCLSLPTIVNGAGREQVLPITLEREEEVALKNSAQILRDVIKQAGL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA_PYRAB
Sequence: MPFEIVFEGAKEFAQLIETASRLIDEAAFKVTEEGISMRAMDPSRVVLIDLNLPASIFSKYEVDGEETIGVNMDHLKKVLKRGKAKETLILRKGEENFLEISLQGTATRTFKLPLIDVEEIEVDLPELPFTAKVVILGDVIKEAVKDASLVSDSMKFIAKENEFTMRAEGETQEVEVKLTLEDEGLLDIEVQEETKSAYGISYLSDMVKGLGKADEVTIKFGNEMPMQMEYYIRDEGRLIFLLAPRVEE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity).  Regulates activity of NucS endonuclease and prevents non-specific cleavage.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: GCH1_HELHP
Sequence: MHNAKRAIFKKRENMQKSSHDSILECNAQAFFESLCQNVGENPTREGLLHTPKRIASAFSDMLNGYAKSPKQALGSVFEDGVCDEMIVLKKLHFYSICEHHLLPFFGHISIGYIPDKKLVGISGLARLTEVFTHRLQIQERLTAQIADALIAELKPKGAMIVCQARHLCLEMRSNVPQSHIITSALRGLFKKDSRTRAEFMQILKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: KCY_NEIG1
Sequence: MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDTGALYRLTALYAQKQGVEWHDEENVSALAKKLPAVFSGNRILLDGEDVSDGIRTEAIGMGASAVAQWPKVRAALLQRQRDFLTEKGLVADGRDTGSVVFPQAELKIFLTAESKIRAERRAKQIGIPCEGFTFERILSDIETRDEADRNRKVAPLKQQPDALLLDTSRLTIEETVKKVLDWYRKV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_FUSNN
Sequence: MFENVVGLIVEYNPFHNGHLHHIQEIDRLFEDNIKIAVMSGDYVQRGEPSLINKLEKTKIALSQGIDIVIELPTFYSTQSAEIFAKGSVNLLNKLSCSHIVFGSESNDLDKLKRIATISLTKEFELSLREFLAEGFSYPTAFSKVLFDEKLGSNDILALEYLRAIKTINSKIEAYCIKREKTGYYDDEKDNFSSATYIRKILLDSNEKKENKLNKIKNLVPEFSYKILEENFGVFSCLSDFYDLIKYNIIKNCSELKNIQDLEIGLENRLYKYSLENLKFEDFFNEVLTKRITISRLQRILLHSLFNLTENITEKVKNEVPFVKILGFSTKGQKYLNYLKKSKNYNERKILTSNRNLKEILNEEEAKLFNFNELCSQIYRIKSSYINIGYPIIKKD
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGG_ECOK1
Sequence: MKHKLQMMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MURC_LACLA
Sequence: MEKTYHFTGIKGSGMSALALMLHQMGKKVQGSDSTDYFFTQRGLEQADVPLLPFDEKNIKPEFELIAGNAFRDDNNVEIAFAHKNGFPFKRYHEFLGHFMEDFTSIGVAGAHGKTSTTGMLAHVMSNIVDTSYLIGDGTGRGIEGSEYFVFESDEYERHFMPYHPEYTIMTNIDFDHPDYFEGIEDVTSAFQDYANNIKKGIFAYGEDVNLRKLTAKAPIYYYGFEANDDYRAENLVRSTRGSSFDAYFRGEKIGHFVVPAYGKHNVLNALSVVAVCHNLGLDMTEVADHLLTFRGVKRRFTEKKVGETVIIDDFAHHPTEIEATLDAARQKYPDREIVAVFQPHTFTRTIAFADEFAEVLDHADTVYLAQIYGSAREVDHHEITAQDLADKVRKPAKVIDLDNVSPLLDHDRGVYVFMGAGNIQKYELAFEKLLSQVSTNLQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEF1_KLULA
Sequence: MGDPVSSKRKSSVSDAVSTSKRQHQQVKVEDVNVPLSSREHSPGPQLHTQQSYYGNGTDGASESALTQSRNNNGATSVVAISDATQNGEDSSNISNNSNAVSKGKAVVNAGHRPVTSCTHCRQHKIKCNASEKFPAPCSRCERMGLHCEIDPQFRPKKGSQLQSLRNDVDELKVKIEYLTRNESLIAKALKQSNIGQNLLQAIKSVDFSYRVAGPTQGQVAKNKISVQTYLTNEPQLLQDSQTTTTNPTTSSNSKVVTPTGSDHSPASHNGGSLSSGKPQLLNDSVPANTKDRLPPVLQIALKRLSQQISSSSPQNSSPTTTGHSPANDLSSSKQHVVATTNAMPLLPSPHANIDEFVLGDVHISIEKATELHNIFVARFLPYFPIMQSNSATELYSQSQLLFWTVILTASLSDPEPTLYNKLSSLIKQLAIETCWIRTPRSTHISQALLILCNWPLPNQKVLDDCSYRFVGLAKSLSFQLGLHRGKFMTEFTRTQTSLPEAEKWRTRTWLGIFFAEQLWASILGLPPTSQTDYLIEKARLGDDGELPPILRKLICLANFQGKLCNVMGTSVVSPDGLMDARERAGSLAILERELERLDVKLKFQEDAAVEIYFLYIKLMICCFAFLPETPTEDQTKYVTEAYLCATKIITLLTKLLETQQLIELPIYIRHSATYSALILFKLYLTPLLLDKYVDSARQSIVTVHRLYRNQLTAWAASVENDISRTASVLEKLNFVLVTHPEVFIEEEGIISRMRSHLTGTLFYDLVWCVHEARRRQMDPNYDAEAAKRNKEKWFKNRRKLYPLPFYNQISKEDFETITQTTPGGTTVTTLVPTKSAIKQAKQLAQSQGDQNGPVTHINGIPLSMLDETGSVNIEGLLANANLNLSNEHSTVLASSSSTATRLNADNPTTDTNKFNVQTVFTHNIKKSSKSSDTPTNKPKFNSTSSIPTATPTSEQRAAHNTKTSASILTGDPNSLFSMNNSLQANIQLNKTLSADSNGTSNNNIPNSTAPLNTPDTNSFNSLTRSPDAPSYGNMNVFYNAANQGTNMNTLYSQSVPNAPQGISAPLSAQPVNVTNIPNGNVNSELDDFFLRQSAGWIEGNSSNDDFLGWFDMNMAPEF
What is the function of this protein?
Putative transcription factor.  Suppresses the lethal phenotype of RPM2 deletion.
What are the official names of this protein?
Putative transcription factor SEF1, Suppressor protein SEF1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_BACMK
Sequence: MTKEQIIEAVKSMTVLELNDLVKAIEEEFGVTAAAPVAVAGGAGEAAAEQTEFDVVLASAGAQKIKVIKAVREITGLGLKEAKELVDNTPKAIKEGVTKEEAEEMKAKLEEVGAAVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS8_PARMW
Sequence: MANHDPISDMLTRIRNASEKRHETTKIPASRMTRSIAKVLQQEGFISEISEQGEGVRTELVLSLKYSGKHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAIISTSKGVMSDRDARREGVGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: A1I3_RAT
Sequence: MKKDREAQLCLFSALLAFLPFASLLNGNSKYMVLVPSQLYTETPEKICLHLYHLNETVTVTASLISQRGTRKLFDELVVDKDLFHCVSFTIPRLPSSEEEESLDINIEGAKHKFSERRVVLVKNKESVVFVQTDKPMYKPGQSVKFRVVSMDKNLHPLNELFPLAYIEDPKMNRIMQWQDVKTENGLKQLSFSLSAEPIQGPYKIVILKQSGVKEEHSFTVMEFVLPRFGVDVKVPNAISVYDEIINVTACATYTYGKPVPGHVKISLCHGNPTFSSETKSGCKEEDSRLDNNGCSTQEVNITEFQLKENYLKMHQAFHVNATVTEEGTGSEFSGSGRIEVERTRNKFLFLKADSHFRHGIPFFVKVRLVDIKGDPIPNEQVLIKARDAGYTNATTTDQHGLAKFSIDTNGISDYSLNIKVYHKEESSCIHSSCTAERHAEAHHTAYAVYSLSKSYIYLDTEAGVLPCNQIHTVQAHFILKGQVLGVLQQIVFHYLVMAQGSILQTGNHTHQVEPGESQVQGNFALEIPVEFSMVPVAKMLIYTILPDGEVIADSVKFQVEKCLRNKVHLSFSPSQSLPASQTHMRVTASPQSLCGLRAVDQSVLLQKPEAELSPSLIYDLPGMQDSNFIASSNDPFEDEDYCLMYQPIAREKDVYRYVRETGLMAFTNLKIKLPTYCNTDYDMVPLAVPAVALDSSTDRGMYESLPVVAVKSPLPQEPPRKDPPPKDPVIETIRNYFPETWIWDLVTVNSSGVTELEMTVPDTITEWKAGALCLSNDTGLGLSSVASFQAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPTSLPMAVLLEASPDFTAVPVENNQDSYCLGANGRHTSSWLVTPKSLGNVNFSVSAEARQSPGPCGSEVATVPETGRKDTVVKVLIVEPEGIKKEHTFSSLLCASDAELSETLSLLLPPTVVKDSARAHFSVMGDILSSAIKNTQNLIQMPYGCGEQNMVLFAPNIYVLKYLNETQQLTEKIKSKALGYLRAGYQRELNYKHKDGSYSAFGDHNGQGQGNTWLTAFVLKSFAQARAFIFIDESHITDAFTWLSKQQKDSGCFRSSGSLLNNAMKGGVDDEITLSAYITMALLESSLPDTDPVVSKALSCLESSWENIEQGGNGSFVYTKALMAYAFALAGNQEKRNEILKSLDKEAIKEDNSIHWERPQKPTKSEGYLYTPQASSAEVEMSAYVVLARLTAQPAPSPEDLALSMGTIKWLTKQQNSYGGFSSTQDTVVALDALSKYGAATFSKSQKTPSVTVQSSGSFSQKFQVDKSNRLLLQQVSLPYIPGNYTVSVSGEGCVYAQTTLRYNVPLEKQQPAFALKVQTVPLTCNNPKGQNSFQISLEISYMGSRPASNMVIADVKMLSGFIPLKPTVKKLERLGHVSRTEVTTNNVLLYLDQVTNQTLSFSFIIQQDIPVKNLQPAIVKVYDYYETDEVAFAEYSSPCSSDDQNV
What is the function of this protein?
Protease inhibitor with a wide spectrum of protein targets, which attaches through its thioester function.
What are the official names of this protein?
Alpha-1-inhibitor 3, Alpha-1-inhibitor 3 variant II, Alpha-1-inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPOL_IIV3
Sequence: MDKPSTKIVNDYTHFYAYSWHVDEESVDETFIRVYGLDEANENVCVSVNGFRQFVWVELPSFIDWSLSHNVDRVVRYFEQTWPNVGVQFKMYRKLYGANLKQSRSNGEYVHKKFPFLQCSSMSWKMLKFTLPTALKTPQRIMGLGSIKFRVHGQDACPRLQLTSKYNLPTAGWIQFKGIEILDQDVKFSQSCREFMVDLSDKNWGKPSTMICRSDKTTVPRPLILSFDLEVNSEEVVTMPKATKPGDVVFQISCIFNRLGGVENEVERYLLSLGNPTEQIVGATILRYSTEKKLLMGFRDLVNEKNPNVITGYNIFNFDIPYLMDRTVYKSIFVEWAQQGFAKNRPGIPREIRWSSSAYKNQEFKYLDCEGRLYIDLLPVVQRDFKLNDYKLKTVSTFFIGETKDDLDPTSIFRCYREGTRDDSPKASHFMSICGKYCMQDSMLVYKLFEKLNVWYGLSEMAVVCNVPMITLFTKGQQIKVYSQLYKYCLAAKIIPEKDGYIVAENERYVGAHVFTPKPGLYENVIPLDFSSLYPSLMIAYNIDYSTCAFDASIPDQLCHIMEWEDHIGCAHDPKVVEKERLTQLINTLKNKEEVSRMRKERSEITKSLSKNVMCEKRKYRFLKSTTEDGRFKGVLPTIVQNMLDARKETRAEMGRLKKRLGTAVGEEATHLQTQIAILNQRQLAYKVSANSMYGITGVKAGMLPFMPVAMSITFMGRTNIARVAQLLQTQYQGELVYGDTDSNYVSFNHKNMSMSELWDYAIRVADEISQQFPPPIKLEFEEAIYSKFLILTKKRYLYQTALRDGTIKKEIGKRGVVLNRRDNSGFIRKIYQNMVDSIFNHVAGEGRDLKSVVLDVVTADICALFNHQFPVDDFVITKSTGNYGDLQPENFVNEKGVPRAMLGQYNVPCLTSQVREEERIETEEQEQNWYLDKLPAHIQLLEKIRRRGQMKNEGGRLEYVIVETNSLKDKQSTKIETLPYYTKNRGILKLDYLYYLHRCINPLDQILKVVFDLDDFVKRQYKAREAKKKVTLELGELFRPNFIIEKSQLQLVRARADEVYRLVYGTAADCRAQLGELGPDWCVRAKFEYVPLVDDPYRYFQQKYGATGSLKTKFDFEGRDIRLNNQPESKLVSTLKREFK
What is the function of this protein?
DNA-directed DNA polymerase involved in viral DNA replication.
What are the official names of this protein?
DNA polymerase 120R.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: RGS4_CHICK
Sequence: MCKGLAALPATCLKSAKDMKHRLGVLLQKSDSCDYGSSQGKKEKVSSSQRVSQEEVKKWAESLENLIHHDRGLAAFRAFLKSEYSEENIEFWVSCEDYKKTKSPAKLSTKARKIYDEFISVQATKEVNLDSCTREKTSHNMLEPTLSCFDEAQRKIFTLMEKDSYRRFLKSPYLDLVSPPRAGCGPENCKRAHAHALDCNSNIISQCA
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein.  Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 4, RGS4.
Protein: QUEA_BRUSI
Sequence: MRVDLFDFDLPEERIALRPVEPRDHAKLLHVRPGEPFEDRHVYDLPDLLQPGDALVFNDTKVIPAQLEGMRERTGNISQVSATLHMRVGPDRWKAFLRPAKRVKEGDRIRFGHSGTSCFLGTLDATVAEKGDSGEALLVFDLSGAVLDEAIAAVGHIPLPPYIASKRPEDERDRKDYQTVYAREEGAVAAPTAGLHFTPDLLEKIKARGIEEHFVTLHVGAGTFLPVKADDTGDHKMHAEIGHVSQRTASALNAVHERGGRIICVGTTSLRLIESATGEDGVVRPWSGATDIFITPGYRFRAVDLLMTNFHLPRSTLFMLVSAFSGLDTMHAAYNYAIADGYRFYSYGDASLLERIDHDRHSA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_AZOVD
Sequence: MLLLLAEYLQQFHTGFAVVQYLTLRGILGVLTALILALCLGPWMIRTLQIRQIGQAVRDDGPQSHLSKKGTPTMGGALILSAIAISTLLWADLSNRYVWTVLAVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLGAALFLYMTAQTPAETTLILPLIKTIEIPLGAAFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPSVAGAGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEVVLFIMGGVFVMETLSVMIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIITVVLVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBHG_ECO24
Sequence: MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGNEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRM2A_HUMAN
Sequence: MSENLDNEGPKPMESCGQESSSALSCPTVSVPPAAPAALEEVEKEGAGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGLQPHKTKLFGQPPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKADPMARRRRQEGESEPPVTRVADVVTPLWTVPYAEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNKACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIPEATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEELAELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLVSRLASQHLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNPRAAMGNFVDLCRAPSNRVKGIPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and some mRNAs (PubMed:31361898, PubMed:33799331, PubMed:34556860).  Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs (PubMed:31361898, PubMed:33799331).  Also able to mediate the formation of 5-methyl-uridine in some mRNAs (PubMed:34123281).
What are the official names of this protein?
tRNA (uracil-5-)-methyltransferase homolog A, mRNA (uracil-5-)-methyltransferase TRMT2A.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: Y2444_RALSO
Sequence: MAIADWPAHERPREKLLTQGPAALSDAELLAIFLRVGMPGKSAVDLARELLAHFGSLGRLCHASRREFSAIHGMGPAKYAQLHALLEVARRALKEEIAYGQTLESPQSVKDFLRLTLGHRPQEVFACLFLDVRHRLIAWEELFQGTLTEARVYPREIAKRALHHNASALILSHNHPTGHVEPSESDLVLTRELCRALALLDVRVLDHMIVGRAEVYSFLEHGKM
What are the official names of this protein?
UPF0758 protein RSc2444.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PFLB_STAAM
Sequence: MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFLAGPTEATSKLWEQVMQLSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQTEKPFKRSMQPFGGIRMAKAACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNCRKAGVITGLPDAYGRGRIIGDYRRVALYGVDFLMEEKMHDFNTMSTEMSEDVIRLREELSEQYRALKELKELGQKYGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTSTFLDIYAERDLKAGVITESEVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESIGGVGIDGRPLVTKNSFRFLHSLDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSSIQYENDDIMRESYGDDYGIACCVSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSGAQVGPNFEGINSEVLEYDEVFKKFDQMMDWLAGVYINSLNVIHYMHDKYSYERIEMALHDTEIVRTMATGIAGLSVAADSLSAIKYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDDRVDDIAVDLVERFMTKLRSHKTYRDSEHTMSVLTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDQKGALSSLSSVAKIPYDCCKDGISNTFSIVPKSLGKEPEDQNRNLTSMLDGYAMQCGHHLNINVFNRETLIDAMEHPEEYPQLTIRVSGYAVNFIKLTREQQLDVISRTFHESM
What is the function of this protein?
Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
What are the official names of this protein?
Formate acetyltransferase, Pyruvate formate-lyase.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_ECOL6
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CH60_CLAMS
Sequence: MAKIIAFDEEARRGLERGLNILADAVRVTLGPRGRNVVLEKKWGAPTITNDGVSIAKEIELDDPFEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGADPISLKRGIEKAVAAVTEELKAAAKEIETKEEIAATASISAGDSTIGAIIAEAIDKVGKEGVVTVEESNTFGTELELTEGMRFDKGYLSQYFVTDPERQEAVFEDAYILIVNSKISNIKDLLPIVDKVIQSGKQLLIIAEDVDGEALATLVVNKIRGIFKSVAVKAPGFGDRRKAQLQDIAILTGGQVIAEEVGLKLENVTLDLLGTARKVVITKDETTIVEGGGDATEIAARVQQIRNEIGNTDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALIQAGKLAFEKLQLEGDEATGANIVRVAVDAPLKQIALNAGLEPGVVAERVRNLPSGHGLNAATGEYVDMLAAGINDPVKVTRSALLNAASIAGLFLTTEAVVADKPEKNPAPAGDPTGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_METRJ
Sequence: MVIQKNWQELIKPNKLQVTTGDDPKRVATVVAEPLERGFGTTLGNALRRVLLSSLQGAAVTSVQIDGVLHEFSSIPGVREDVTDIVLNIKTIAIRSQTDAPKRMTLRKTGPGLVTAGDIGTVGDIQILNPDLVICTLDDGAEIRMEFTVATGKGYVPAERNRPEDAPIGLIPVDSLFSPVTKVSYRVETTREGQDLDKDKLTMTVETNGAVSPEDALAYAARIIQDQLQVFVNFEDPRKEEAAPLAPQLPFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKSEGEMLRTPNFGRKSLNEIKEVLAGMGLHLGMDIPGWPPENIEDLAKRFEEHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: WSP1_SCHPO
Sequence: MPPSSSITQEDKATIRKYIPKSTNKIIAAAVVKLYVAYPDPNKWNYTGLCGALVLSYDTTAKCCWFKLVDVVNNSGIIWDQELYQNMDYRQDRTFFHSFELDKCLAGFSFANETDAQKFYKKVLDKGCHPESIENPVLSFITRKGSSRHAPNNSNIQPPSAAPPVPGKENYNAVGSKSPNEPELLNSLDPSLIDSLMKMGISQDQIAENADFVKAYLNESAGTPTSTSAPPIPPSIPSSRPPERVPSLSAPAPPPIPPPSNGTVSSPPNSPPRPIAPVSMNPAINSTSKPPLPPPSSRVSAAALAANKKRPPPPPPPSRRNRGKPPIGNGSSNSSLPPPPPPPRSNAAGSIPLPPQGRSAPPPPPPRSAPSTGRQPPPLSSSRAVSNPPAPPPAIPGRSAPALPPLGNASRTSTPPVPTPPSLPPSAPPSLPPSAPPSLPMGAPAAPPLPPSAPIAPPLPAGMPAAPPLPPAAPAPPPAPAPAPAAPVASIAELPQQDGRANLMASIRASGGMDLLKSRKVSASPSVASTKTSNPPVEAPPSNNLMDALASALNQRKTKVAQSDEEDEDDDEWD
What is the function of this protein?
Has a role in regulating actin assembly, so regulating polarized growth.
What are the official names of this protein?
Actin-binding protein wsp1, Wiskott-Aldrich syndrome protein homolog 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL31_PROMP
Sequence: MPKSEIHPKWYPDAKVICNGEVVMTTGSTKPELHVDVWSGNHPFFTGTQKILDTEGRVDRFMKKYGMGSADSATSKETKESKKSDK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ACEK_ECO5E
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_ASPOR
Sequence: MLRPWLRQSTRAARSLPCCQCPRPYSSRLPTLTSPSSSVRRLQTSASESQDRVPLRKQLKQNAKALKAEKRQRRESEEASRQKWELTVGIEIHAQLNTETKLFSRASTSSTDLPNSNVALFDLAFPGSQPEFQVPTLLPALRAALALNCDIQPVSRFDRKHYFYQDQPAGYQITQYYEPFARNGYVDLFGYDGIAPEDGDHVRIGIKQVQLEQDTAKSQEYHPSTQLLDFNRVSHPLVEIITMPQIHTPATAAACVRKIQAILQSCSAVTTGMELGGLRADVNVSIRQRGDTEGVHQYGGIGGLGQRTEIKNLSSFKAVEDAIIAEKNRQIAVLESGGVVEGETRGWTIGSTETRRLRGKEGEVDYRYMPDPDLPPLLIGADLVSELANTLPTSSDELIGLLTGKEYGLSIEDAKPLVELEDGARLEYYQDVVDILRDLQQDQDPKSRGGLARVAGNWVLHELGGLLTKADLPWDAERVSALSLAQIIDHVQRKQITGPTAKQVLAMVFDGDTRAIPQLLEEENLLLRPLSREEYVALAEAAISQNPQMVEQIRTKNQLGKLGWFVGQMMRMGEKGRVEAPKADAILRELILG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.