PharMolix/UniProtQA huggingface dataset:
Protein: NXF1_RAT
Sequence: MADEGKSYNEHDDRVSFPQRRKKGRGPFRWKCGVGNRRSGRGGSGIRSSRFEEDDGDVAMNDPQDGPRVRFNPYTTRPNRRRDTWHDRDRIHVTVRRDRAPQERGGAGTSQDGTTKNWFKITIPYGKKYDKMWLLSMIQSKCSVPFNPIEFHYENTRAHFFVENATTASALKAVNYKIQDRENGRISIIINSSAPPYIVQNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRGCMAAALRIIEENIPELLSLNLSNNRLYKLDDMSSIVQKAPNLKILNLSGNELKSEWELDKIKGLKLEELWLDRNPMCDTFLDQSTYISTIRERFPKLLRLDGHELPPPIAFDVEAPTMLPPCKGSYFGTENLKSLVLHFLQQYYAIYDSGDRQGLLDAYHDGACCSLSTPSNPQNPVRHNLAKYFNDSRNVKKIKDTTTRFRLLKHTRLNVVAFLNELPKTHHDVNSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFIAVPASNSGLCIVNDELFVRNASPEEIQRAFAMPAPTPSSSPVPTLSQEQQDMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK
What is the function of this protein?
Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway).  The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex.  ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.  Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.
What are the official names of this protein?
Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Nucleus, nuclear pore complex. Nucleus envelope. Cytoplasm. Cytoplasm, Stress granule. Note=Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. The association with the TREX complex seems to occur in regions surrounding nuclear speckles known as perispeckles. Nucleus; nuclear rim.
Protein: MUTL_PSEAB
Sequence: MSETPRIQLLSPRLANQIAAGEVVERPASVAKELLENSLDAGSRRIDVEVEQGGIKLLRVRDDGRGIPADDLPLALARHATSKIRELEDLERVMSLGFRGEALASISSVARLTMTSRTADAGEAWQVETEGRDMQPRVQPAAHPVGTSVEVRDLFFNTPARRKFLRAEKTEFDHLQEVIKRLALARFDVAFHLRHNGKTIFALHEARDELARARRVGAVCGQAFLEQALPIEVERNGLHLWGWVGLPTFSRSQPDLQYFYVNGRMVRDKLVAHAVRQAYRDVLYNGRHPTFVLFFEVDPAVVDVNVHPTKHEVRFRDSRMVHDFLYGTLHRALGEVRPDDQLAPPGATSLTEPRPTGAAAGEFGPQGEMRLAESVLESPAARVGWSGGSSASGGSSGYSAYTRPEAPPSLAEAGGAYKAYFAPLPAGEAPAALPESAQDIPPLGYALAQLKGIYILAENAHGLVLVDMHAAHERITYERLKVAMASEGLRGQPLLVPESIAVSEREADCAEEHSSWFQRLGFELQRLGPESLAIRQIPALLKQAEATQLVRDVIADLLEYGTSDRIQAHLNELLGTMACHGAVRANRRLTLPEMNALLRDMEITERSGQCNHGRPTWTQLGLDELDKLFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PNP_PSESM
Sequence: MNPVIKKFQFGQSTVTLETGRIARQASGAVLVTVDDDVSVLVTVVGAKQADAGKGFFPLSVHYQEKTYAAGKIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGFMNEVQVVCTVVSTSKKIDPDIAAMIGTSAALAISGIPFDGPVGAARVAFHESTGYLLNPTYEQLQASSLDMVVAGTSEAVLMVESEAKELTEDQMLGAVLFAHDEFQVVINAIKELAAEAAKPTWDWQPKPEATALLGAIRAEFGDAISQAYTITVKADRYARLGELKDQVVAKLAVEEGSPSAGEVKAAFGEIEYRTVRENIVNGKPRIDGRDTRTVRPLNIEVGVLPKTHGSALFTRGETQALVVATLGTARDAQLLDTLEGEKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRSVQAMLPGADVFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVKEGEKFAILTDILGDEDHLGDMDFKVAGTSKGVTALQMDIKIKGITEEIMEIALGQALEARLNILGQMNQIIGQSRNELSANAPTMIAMKIDTDKIRDVIGKGGATIRAICEETKASIDIEDDGSIKIFGESKEAAEAARQRVLGITAEAEIGKIYLGKVERIVDFGAFVNILPGKDGLVHISMLSDARVEKVTDILKEGEEVEVLVLDVDNRGRIKLSIKDVAAAKASGV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFG_ECOLU
Sequence: MMSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGR
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_STUER
Sequence: MTNIRKTHPLLKIINNSLVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLVMLTALSALVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILTIVPILHMSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLILLVLMPLTSITENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SEM12_ARATH
Sequence: MAAEPKAAVEVVKVDLFEDDDEFEEFEINEDWLEKEEVKEVSLQWEDDWDDDDVSDDFSRQLKKELENASEKK
What is the function of this protein?
Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis (By similarity).  Associates also with the TREX-2 complex that is required for transcription-coupled mRNA export (PubMed:19843313).
What are the official names of this protein?
Protein DSS1 HOMOLOG ON CHROMOSOME V, AtDSS1(V), Probable 26S proteasome complex subunit sem1-2.
What is the protein family that this protein belongs to?
Belongs to the DSS1/SEM1 family.
Protein: YOX2_SCHPO
Sequence: MRNLNTELDFFVSFSALKEENISQLKVYWAQSNLVELYYGESFYINIVCSRPIVDENVTTWPENEGFRIEGTLLESLVESVTSASNYPKVNAFSLMCSGIPSFIWVEDDKQYALWACLAQLDSYSYPNHKLEIHVYKHILPDLPQSSEVDRNSETEGTREENSNTSDWDEQNEYVSEVEGDYNLLGSLSNDIQFRSNPPVISGAYVFGESDVANELKDPSRKTKTRKKVFECSVPVVLKLRSYALNESNQYITSIVSPDSSCENIRILGFKAETNAATISLFAPKTPEKLQITLSSSDVFTIIHLLQIPDNIKHIELQCFCKVIVAQKLSETLVESMPFTYKHPPVLITRRTPTKTHTKQLSSSGNVSAAQSISSLNLLEISASSPSYVPSGSSFSVRANLYNPLDFSIDLLIRIPLYCYDDCLTNKEHSTSKSEEKSSELLKYPNGHTISPGIIALSTKLYTGSIFPKCEKDFDLHFLAYKPGSYDLSSISIEDVNHVVHKPRKLSKELQIIVT
What are the official names of this protein?
Uncharacterized protein C14F5.02.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PT311_ARATH
Sequence: MKIAANGRFFTIGLVASWYSSNIGVLLLNKYLLSNYGFKYPIFLTMCHMTACSLLSYVAIAWMKMVPMQTIRSRVQFLKIAALSLVFCVSVVFGNISLRFLPVSFNQAIGATTPFFTAVFAYLITFKREAWLTYFTLVPVVTGVVIASGSEPSFHLFGFIMCIAATAARALKSVLQGILLSSEGEKLNSMNLLLYMAPIAVVFLLPATLIMEKNVVGITIALARDDFRIVWYLLFNSALAYFVNLTNFLVTKHTSALTLQVLGNAKGAVAVVVSILIFRNPVSVTGMLGYSLTVCGVILYSEAKKRSK
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At3g11320.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TF2B7_HALSA
Sequence: MTRSTRQRERETAAKQEEEEDSEEGVRECPECGSDNLVKSSDRAELVCNDCGLVVEEEQIDPGPEWRAFNHQERQEKSRVGAPTTQTMHDKGLTTTIDWKDKDAYGRSISSKKRSQMHRLRKWQERIRTKDAGERNLQFALSEIDRMASALGVPRSVREVASVIYRRALKEDLIRGRSIEGVATSALYAACRKEGIPRSLEEISEVSRVERKEIGRTYRYISQELGLEMKPVDPKKYVPRFCSELELTEEVQSKANEIIETTAEEGLLSGKSPTGYAAAAIYAASLLCNEKKTQREVADVAQVTEVTIRNRYQEQIEAMGIHG
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 7, TFIIB 7.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: RL22_RHOBA
Sequence: MSQFNAYHKNARISAQKVRLVADLVRGMFADEALDTLKYQPQRGARMLEKVIKSAVGNAQDPDQNSGRSHRIEELVITDVRVDGGPMFKRIQPRARGMAFMIKKRSSHIRVGLTHIENV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SYY_ECO55
Sequence: MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEDGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFC_SALTI
Sequence: MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIGLFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAIPLVAMIPLLAASGASTTLGAFALSALKVAGALALVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARTLGVPAKQRRWFAVLLGQGSEFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKTHFPHLQIIARARDVDHYIRLRQAGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFCHFNTRMVEEMAKGENDPLSRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGKAADEPEVKPSI
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPQQE_HELPY
Sequence: MKHFSVKRLLGLSSVLLVTLGASMHAQSYLPKHESVTLKNGLQVVSVPLENKTGVIEVDVLYKVGSRNETMGKSGIAHMLEHLNFKSTKNLKAGEFDKIVKRFGGVSNASTSFDITRYFIKTSQANLDKSLELFAETMGSLNLKEDEFLPERQVVAEERRWRTDNSPIGMLYFRFFNTAYVYHPYHWTPIGFMDDIQNWTLKDIKKFHSLYYQPKNAIVLVVGDVNSQKVFELSKKHFESLKNLDEKAIPTPYMKEPKQDGARTAVVHKDGVHLEWVALGYKVPAFKHKDQVALDALSRLLGEGKSSWLQSELVDKKRLASQAFSHNMQLQDESVFLFIAGGNPNVKAEALQKEIVALLEKLKKGEITQAELDKLKINQKADFISNLESSSDVAGLFADYLVQNDIQGLTDYQRQFLDLKVSDLVRVANEYFKDTQSTTVFLKP
What is the function of this protein?
Virulence factor that cleaves the cytoplasmic domain of the human junctional adhesion molecule A (JAM-A), compromising gastric epithelial barrier function and cell-cell adhesion (PubMed:33970782).  Cleavage of JAM-A occurs after Ala-285 or, to a lesser extent, before Ala-285 (PubMed:33970782).
What are the official names of this protein?
Zinc protease PqqE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_CLONN
Sequence: MELFNKTAHELIDMIKSKEVKVEEVVKSYIARTECIDEKIGAYLYLSKESALKEAKLLDEKIQRGEKLKGLWGVPVGIKDNISVSGMQNTCASKILENYISPYDATVISRLKENNGIILGKLNMDEFAMGSSNENSAFKIVRNPWDLERIPGGSSGGSTAAVASREIPLSLGSETGGSVRQPAALCGVVGLKPTYGRISRYGVISFASTLDQVGTIGRDVTDCAILTEVISGFDKRDSTSARVAVPNYKESLKKDLTGIRIGLPKEFFKEDLDESIRKQIEDAIKILEKNGAEIKICSLPLAEYSLSAYYIISTAEASSNLARIDGIRYGRRINTLDKHEDIYIQSRNEGFGEEVKKRIMLGTYVLSKGCYEKYYEKALKVRTLIKEDFKRVLKEVDAIITPTSKVTAFKFGERTKEVLSMYSSDEYTVPASIAGLPAISIPCGFSKGLPVGFQLIGDYFREDILFNIGYSYEQSTDFHKIMAKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: XERC_STAAC
Sequence: MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO1_CAEEL
Sequence: MHRASLICRLASPSRINAIRNASSGKSHISASTLVQHRNQSVAAAVKHEPFLNGSSSIYIEQMYEAWLQDPSSVHTSWDAYFRNVEAGAGPGQAFQAPPATAYAGALGVSPAAAQVTTSSAPATRLDTNASVQSISDHLKIQLLIRSYQTRGHNIADLDPLGINSADLDDTIPPELELSFYGLGERDLDREFLLPPTTFISEKKSLTLREILQRLKDIYCTSTGVEYMHLNNLEQQDWIRRRFEAPRVTELSHDQKKVLFKRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGVDSFVIGMPHRGRLNVLANVCRQPLATILSQFSTLEPADEGSGDVKYHLGVCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDRTMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDPRSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVIVDLVCYRRHGHNELDEPMFTQPLMYQRIKQTKTALEKYQEKILNEGVANEQYVKEELTKYGSILEDAYENAQKVTYVRNRDWLDSPWDDFFKKRDPLKLPSTGIEQENIEQIIGKFSQYPEGFNLHRGLERTLKGRQQMLKDNSLDWACGEALAFGSLLKEGIHVRLSGQDVQRGTFSHRHHVLHDQKVDQKIYNPLNDLSEGQGEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWEAQFGDFSNTAQCIIDQFISSGQSKWIRQSGLVMLLPHGYEGMGPEHSSARPERFLQMCNEDDEIDLEKIAFEGTFEAQQLHDTNWIVANCTTPANIYHLLRRQVTMPFRKPAVVFSPKSLLRHPMARSPVEDFQSGSNFQRVIPETGAPSQNPPDVKRVVFCTGKVYYDMVAARKHVGKENDVALVRVEQLSPFPYDLVQQECRKYQGAEILWAQEEHKNMGAWSFVQPRINSLLSIDGRATKYAGRLPSSSPATGNKFTHMQEQKEMMSKVFGVPKSKLEGFKA
What is the function of this protein?
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TRPB1_METAC
Sequence: MTETKVSEFQLKGKYGKYGGQYVPEVLMPALEELDVGYEKYKNDPESLAELDHYLRDFAGRETPLYFARNLSKKYGTKVYLKREDLVHGGAHKLNNALGQALLAKFMGKTRLIAETGAGQHGTATAMVGATLGFETIVYMGAKDIKRQQMNAYRMELMGTEVRAVETGSKTLKDAINEAMRDWVTNIENTHYLIGSVVGPHPYPMIVRDFQSVIGKEVKEQAMEKEGRLPDSIIACAGGGSNAMGTFHPFIEDREVKLIAVEAGGKGLKCTEKAALHSASLCIGEEGILHGARTKILQDKNGQILESESVSAGLDYSGVGPELAYLSESGRVTARYVTDDEALDAFNELSRLEGIIPALESSHALAYLKKAAESGELGEFVVVNLSGRGDKDLETVLSLRRGV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RPOC1_BUXMI
Sequence: MIDRYKHQQLRIGLVSPQQISAWANKILPNGEIVGEVTKPYTFHYKTNKPERDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRIPSYIANLLDKPLKELEGLVYCDFSFARPVAKKPTFLRLRGSFEYEIQSRKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADPDLRIITDYSLGEWKELGEEGPTGNEWEDRKIGRRKDFLVRRMELAKHFIRTKVEPERMVLCLLPVLPPELRPIIQIDGGKSMSSDINELYRRVIYRNNTLIDLLTTSRSTPRELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHVASNIGVAKSKIREKEPIVWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSGNRRGICANRYNPCNRGNRVNFQNERIDDNNYKYTKEKDPYFCSSYDAIGAYRQKRINLDSPLWLRWRLDQRIIASREVPIEVHYESLGTYHEIYVNYLIVKSVKKEILCIYIRTTVGHIYFYRKIEEAVQGFFRACSYGT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DBP5_ASPFU
Sequence: MASEQPVEAAPTGGSLADRITKPDESNTSETPAPIGDQTDGAPAQLGGSDLHEPEYNVEVKLSDLQADPNNPLYSVKNFEDLGLDPRILKGLSSMNFRKPSKIQERALPLLLNNPPKNLVGQSQSGTGKTAAFVLNALSRVDLSTEQMQKTPQALILAPTRELARQILGVVQVMGQFVDGLIIGAAVPTDRDSRPKRLECSIVVGTPGTVGDMIKRRTFIPNKLKVLVLDEADNMLDQQGLGDQCIRVKALLPRDIQVVLFSATFPEHVHQYASKFAPNANEITLQHEELTVEGIKQLYLDCADGEDKYRTLVQLYGLLTVGSSIIFVQTRAAAQEIERRMTAEGHTVVSLTGERDPSVRDAIIDQFRRGEAKVLIATNVLARGIDVSTVSMVINYDIPELHQPNVPGRQADFQTYLHRIGRTGRFGRVGVSISFVSNREEWEMLNQIQTYFNCEIQRVDTKDWDEVEDIIKKTIKNSRANPKFAGGKD
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: SMCO4_BOVIN
Sequence: MRQLKGKPKKETSRDKKERKQAMQEARRQITTVVLPTLAVVVLLIVVFVYVATRPASTE
What are the official names of this protein?
Single-pass membrane and coiled-coil domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the SMCO4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PDRP_NITWN
Sequence: MAPGTGRDFHLHLVSDSTGETLITVSRAVTAQYAGVTPIEHVYPLVRSEKQLDRVLAEIEEAPGIVLFTLLEKDVAVRLEARCQEINCPSLSIIGPVMQLFQAYLGADTTGRVGAQHTLNADYFKRIDALNYTMMHDDGQHVESLEEADVVLVGVSRTSKTPTSVYLANRGTRTANVPLVPGIAIPRQLETLKNPLVVSLHAAPERLIQVRQNRLLSIGAGPGNEAYIDRQSVTEEVIHARRLSVKHDWAQLDVTRRSIEETAAAIMKLFADRRRQRRPD
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: TRPD_SULSY
Sequence: MIKDIIKKLTERQDLTKEEMTYLFDNLMEGNLTDAQIGAVLIGLKMKGESVLEIETAARIMKEKAVKVVVKDKSKLVDTCGTGGDRLNTFNVSTISAFVVAGAGGKVAKHGNRSISSKCGSADIMEALGIKIELTAEEVSRQIEEIGLGFMFAPLFHPSMKNVIKQRREIGVRTIFNILGPLSNPADANYQVMGVYDKSLVEPLTKVLQNLGVKKAYVVHGLDGLDEVSITAETYVGEINESDINFYTVKPEDFGLKRAEIFEIQGGDVECNKEIALSILQGKDYSSKTDFVALNSAFALKVIGLVDSIKDGIDLAKETIYNKKGYEVLEKLRNFS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SDHF2_YEAS1
Sequence: MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDKDDHDDVVTRIKISPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLNELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKEILSMPDLSKYQ
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MSRB1_PIG
Sequence: MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSHSKYAHSSPWPAFTETIHADSVAKRPEHNRPGALKVSCGRCGNGLGHEFLNDGPKRGQSRFUIFSSSLKFIPKGQESSPSQGQ
What is the function of this protein?
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine.  While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue.  Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization.  Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B1, MsrB1, Selenoprotein X, SelX.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton.