PharMolix/UniProtQA huggingface dataset:
Protein: DMA_MOUSE
Sequence: MEHEQKSGAVLLRLLRLLWLLPHSWAVLEASTPVLWDDPQNHTFRHTLFCQDGIPNIGLSETYDEDELFSFDFSQNTRVPRLPDFAEWAQGQGDASAIAFGKSFCEMLMREVSPKLEGQIPVSRGLSVAEVFTLKPLEFGKPNTLVCFISNLFPPTLTVNWQLHSAPVEGASPTSISAVDGLTFQAFSYLNFTPEPFDLYSCTVTHEIDRYTAIAYWVPQNALPSDLLENALCGVAFALGVLGTIIGIVFFLCSQRPCSGD
What is the function of this protein?
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides.
What are the official names of this protein?
Class II histocompatibility antigen, M alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Protein: RECF_SHIFL
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMDDTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O10R2_HUMAN
Sequence: MPQILIFTYLNMFYFFPPLQILAENLTMVTEFLLLGFSSLGEIQLALFVVFLFLYLVILSGNVTIISVIHLDKSLHTPMYFFLGILSTSETFYTFVILPKMLINLLSVARTISFNCCALQMFFFLGFAITNCLLLGVMGYDRYAAICHPLHYPTLMSWQVCGKLAAACAIGGFLASLTVVNLVFSLPFCSANKVNHYFCDISAVILLACTNTDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSAEGRRKAFSTCASHLSVVIVHYGCASFIYLRPTANYVSNKDRLVTVTYTIVTPLLNPMVYSLRNKDVQLAIRKVLGKKGSLKLYN
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10R2, Olfactory receptor OR1-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EAT2_HANUV
Sequence: MIFNSLSIKRLSSTXTSLPFKKHAKLNFDLYSPQHSTYGKLPYHCQEPIIFLHGIYGYSKSFNSDYQQLSNLLHTPIYSVDMRCHGETENCLPFTYDALAGDLDNFVITHNIKKPSLIGFSLGAKLAMLAILKSPHLYTSGVIVDNVPLKQPRIKPNLTAFGNALRDSVFKSGVKRNDPSWISKSFNVMKDVCSDMPANFYLLHNIQPKPSYLKKYSTEESENSLFCKVPIRELSSHVVENVPDWPEEDLAGVKTDVPILVVKASTSGFVNEDGVAALXKHFSDFTIVEVAGTHLVMKERPQEYISAVGRWFYQQNCKKAAALTKAKKTNDQKITQQPILSYKKIEIA
What is the function of this protein?
Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA (PubMed:28356220).  Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate (By similarity).
What are the official names of this protein?
Ethanol acetyltransferase 2, Acetyl-CoA hydrolase, Acetyl-CoA thioesterase, Alcohol acetyltransferase, AAT, Ethyl acetate esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PURT_FRATO
Sequence: MNISNIKIMLLGSGELGKEFIIAAQRLGIHTIAVDRYKNAPAMQVAHESYVIDMLNSDALEQLILAKNPTYIVPEIEAINTDSLVKLEAHNFNIIPCAKATKLTMDRQGIRALAVQQLNLQTSKFAFANSEQEYLDVIQSIGLPFVIKPVMSSSGKGQSIVKEHNEIKKAWDYAQNGSRGHAKGVIVEQFIDFDYEITLLTVRHKDGTSFCDPIGHIQKDGDYRFSWQPHTMPDTALAKSQEIAKEITDALGGYGVFGVELFIKGDEVFFNEVSPRPHDTGMVTLISQNINEFELHLRAIVGLPIPDIQTLQPSASAAILLEGDTANASICGIDKALADANVDIRIFSKKEIHGKRRMGVVLAKAQNTHIALETSKQALAHIHLTK
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MAZF3_MYCTO
Sequence: MRPIHIAQLDKARPVLILTREVVRPHLTNVTVAPITTTVRGLATEVPVDAVNGLNQPSVVSCDNTQTIPVCDLGRQIGYLLASQEPALAEAIGNAFDLDWVVA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Acts as an endoribonuclease, cleaving in U-rich regions.  Neutralized by cognate antitoxin MazE3.
What are the official names of this protein?
Endoribonuclease MazF3, Toxin MazF3, mRNA interferase MazF3.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: LPLT_ECO45
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHILVALVACALAYGGAVVANIYIPKLAAARPGQSWNLISMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHS_NITEU
Sequence: MTNVCDLTDRKCKPCEGGVPPLEMEEAEKLLKQLEQGWQLADNKISRTFSFKNYYQTMAFVNAIAWVSHREDHHPDMMVGYDWCRVEYMTHAIGGLSENDFICAAKVDMLFKS
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: HIS2_BUCAI
Sequence: MLKKHDLLNLDWTKTNGMIPVIIQDYSSSEVLMHGYMNQDALTKTQEDGLVTFYSRTKNCLWTKGEISGNYLKVIEISTDCDNDTLLILVAAQGKTCHLGNSSCFISNKYNINFLFKLEEIIEERKNKFSDNSYTSSLYKSGTSRIAQKVGEEAIETILAAMNKDQIELINEASDLIYHLVVLLHDQDLNFNLVIDNLKKRREKNLNTNSEKLLK
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTC_PHOLL
Sequence: MLENIQRSWFEHYMVPCFSPAKFIPVRAKGSKVWDQDGKEYIDFAGGIAVNSLGHAHPELKDELIYQIDKIWHIGNGYTNEPVLKLAKRLVENTFADKAFFCNSGAEANEAALKLARKYAADKYGKNKNEIISFKDSFHGRTLFTVTVGGQPKYSQDYAPLPQEITHLPYNNLSAIREHISENTCAVIVEPIIGEGGVIPADPAFLQELRTLCDRFQALLIFDEIQTGVGRTGYLYAYQEYGVEPDILTSAKGLGGGFPIGAMLTKQHIAAVFQPGTHGTTFGGNPLATAVANKVLSIVNQAELLTGVLQRHDYFMDKLSKLNQRYQIFSCLRGKGLLLGAELDKAWQGKAKQLTNLAAEEGLIALIAGPDVLRFAPALNIEFADIDEGLVRLESAIMRFVG
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, SOAT, Carbon starvation protein C, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: RL2_EXIS2
Sequence: MGIKKFKPTTNGRRNMTALDFAEITASRPEKSLTEKLSKKGGRNNQGRLTVRHQGGGHKRKYRIIDFKRNKDGIAGRIATIEYDPNRSANIALVHYIDGEKRYILAPKGLKVDMQVMSGVEADIKVGNALPLSNIPVGTLIHNIELKPGKGGQLVRSAGTSAQLLGKDGKYAIVRLQSGETRMILATCRATVGAVGNEEHELVNIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRAPIGRSGPLTPWGKPALGYKTRKKNKASDKYIVRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NOP9_AJEDR
Sequence: MPRERQKRGRRAEAKRKRDDEVGDRTAPKRQKASEGDNDFNPLHSQAKIGDDYIPLEEEPASSMDTPFYGLLDPDEQEYFSHASGLLELNQFETEEEKSIFIERVYEEADGKELKIACSQSCSRLMEKLISASTVSQIKSLFNKFVGQFLNLVQHRFASHCCESLFLRAAPYVTLEMKKKSAEKNDNEGEDSSANLRLEDLFLAVLSELEGNWGYLLTERFASHTIRVLLLILAGEQLDNPSKATVIASRKKENLDKPKVTQRDKSASDRRAVPPSFNAALEKMMNDLVTGLDNTYLRALATHPVGNPVLQVLLSVELTHLGKSKARDPDSVFRRLVPDENLEEGSESAAFIKGLFYDPVGSRLLETMVQLAPGKFFKTFYKALVQERIGSLSRNEIAGHVVARILERLSKEDLKSSMDLILPEVLSLVKRSRFTVIKTLIERGVIRGVDLRPLADSLLLAFGTDPIARINNVLKLHHLNEENDDTKRSSKNSTPEQLHGSLLAQTMLKAPGPLSELIQSSLLAVTLETLIAIAKDPVASHVLQDALTLPTSTIQFRRQITSRFSGKMAELALDSSGSHVVDAVWSATENLIFIKQRFAEELLANERPLRDSFVGRAVWKNWSMDLYKRRRGHWIAVAKGLESVNPSNSENRQPPKSNLDLARARFAEKSNTSTPKKITATF
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: URED_MYCGI
Sequence: MTAPTIQPGELGIEVVADSAGRTRTASLRQRYPQRVTMPLHCDPDRPGAVTLCVQSPSGGTFSDDELRTTVACRAGSHLHLTTQSATQVFAGDGAGARHHLDFTVDRGAALEYYPGTVIPHTDSTFTQTIEVNVETGGLYLGWEAVAAGRLAHGERYGYHTYDSAILARVDGRAVARDRQVIRPGTDAMSLLEGDYLATLLVVAPGADIEALLRRLRATLDDGSGVSGGAGRLPAHAGVFLRLIAQRAPDLHRARTDLFAAARRELLPGKDES
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWT1A_ORYSJ
Sequence: MEHIARFFFGVSGNVIALFLFLSPVVTFWRIIKKRSTEDFSGVPYNMTLLNCLLSAWYGLPFVSPNNILVTTINGTGSVIEAIYVVIFLIFAERKARLKMMGLLGLVTSIFTMVVLVSLLALHGQGRKLFCGLAATIFSICMYASPLSIMRLVIKTKSVEFMPFLLSLSVFLCGTSWFIYGLLGRDPFIAIPNGCGSFLGLMQLILYAIYRNHKGATPAAAAGKGDAADEVEDAKKAAAAVEMADAKTNKVVADDADADADGKSADDKVASQV
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET1a, OsSWEET1a.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIT1_YEAST
Sequence: MDPGIANHTLPEEFEEVVVPEMLEKEVGAKVDVKPTLTTSSPAPSYIELIDPGVHNIEIYAEMYNRPIYRVALFFSLFLIAYAYGLDGNIRYTFQAYATSSYSQHSLLSTVNCIKTVIAAVGQIFFARLSDIFGRFSIMIVSIIFYSMGTIIESQAVNITRFAVGGCFYQLGLTGIILILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAIDANWKWGIGMWAFILPLACIPLGICMLHMRYLARKHAKDRLKPEFEALNKLKWKSFCIDIAFWKLDIIGMLLITVFFGCVLVPFTLAGGLKEEWKTAHIIVPEVIGWVVVLPLYMLWEIKYSRHPLTPWDLIQDRGIFFALLIAFFINFNWYMQGDYMYTVLVVAVHESIKSATRITSLYSFVSVIVGTILGFILIKVRRTKPFIIFGISCWIVSFGLLVHYRGDSGAHSGIIGSLCLLGFGAGSFTYVTQASIQASAKTHARMAVVTSLYLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAYGSPFTFITTYTWGTPERIALVMSYRYVQKILCIIGLVFCFPLLGCAFMLRNHKLTDSIALEGNDHLESKNTFEIEEKEESFLKNKFFTHFTSSKDRKD
What is the function of this protein?
Involved in the transport of siderophore ferrioxamine B and so has a role in iron homeostasis.
What are the official names of this protein?
Siderophore iron transporter 1, Ferrioxamine B permease, Siderophore iron transporter ARN3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: COAA_LISW6
Sequence: MNDYNHYFHFPREEWRKLEVSKDQILTAEELEEIRGLNDRISLQDISEIYLPLIKLIAIQYHEAIFIHGEKMEYLKKKESRAPFIIALAGSVAVGKSTTARVFKLMLDRWFSKTRQVELVTTDGFLFPNKVLEERGIMNKKGFPESYDRDRFAKFLTDLKTNKEAVEVPLYSHFTYDVLDETRMMHNPDIVIIEGINVLQADQHESLFPSDFFDFSVYMDAAEADIKKWYLERFFMLRETAFQDKSSYFHQYTKINKKEAETFALGVWDTINGVNLKENIEKTKYRADLVLHKGTDHLISDIYLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_RICAH
Sequence: MSFKPLHDRIAIKPIEHEEKTKGGIIIPDTAKEKPMQGEIVAVGNGVRNKKGEIHPLELKVGDKVLYGKWAGTEIEIKGEKLIVMKESDVFGIIN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPTC2_RAT
Sequence: MRPEPGGCCCRRPMRANGCVKNGEVRNGYLRSSTATIAAAGQIHHITENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRPLPLLDRPFDETTYEETED
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate (By similarity).  Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase 2, Long chain base biosynthesis protein 2, LCB 2, Serine-palmitoyl-CoA transferase 2, SPT 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TRPC_STAAR
Sequence: MTILEEIVEYKQLLLQNGYYQDKLNTLKSVNIQNKKSFINAIEKEPKLAIIAEIKSKSPTVNDLPERDLSQQISDYEQYGANAVSILTDEKYFGGSFERLQALTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEVLVEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKPNHYYISESGIHDVSDVRKILHSGIDGLLIGEALMRCDNLSEFLPQLKMQKVKS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RL30_ECOHS
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TSAD_SYNS9
Sequence: MQTVLALETSCDESAAAVVRHKADGSVEVLASRIASQVEEHALWGGVVPEIASRRHVEALPALVQEVLRESALSISELNAVAATVAPGLAGALMVASVTGRTLAALHQVPFLGIHHLEGHLASAALGEQAPAPPYLVLLVSGGHTELIRVGLNGEMERLGRSHDDAAGEAFDKVARLLGLGYPGGPAIQAIAVSGNAKRFSLPKGRISLRGGGFHPYDFSFSGLKTAMLRTVESCQSSGGDLPLADLAASFEQVVADVLVERAIRCALDHNLTQLVMVGGVAANQRLRLLMAKQGKQHGVAISIAPLAYCTDNAAMIGAAALNRLSRGVLSSSDETGVAARWPLERADALYDASPAF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_RHIL3
Sequence: MKASDVRAFTADQLKDELAKLKKEQFNLRFQKATGQLEKSSRINEVRKDIARVKTIARQKAAEVKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DCD_TERTT
Sequence: MSIKSDKWIRRMAEQEGMIEPFEPGQIRYDSNNQKLVSYGTSSYGYDVRCAREFKIFTNVHSAVVDPKNFDEHSFVDISSDVCIIPPNSFALARTVEYFRIPRSVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGIAQMLFFESDEICDTSYRDRGGKYQGQTGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: BFE_SHEON
Sequence: MKDRHGLLSAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEALAAISFTFPVTLIISSIAIGVGAGVSTNLGRLIGSGNAPQAKVFLHDALLLTFILIASLSALGSIFIEPLFSLLGANETSLPLIHDYMMYWYVGAPLLVLLMVGNQGLRSTGDTRSPAMIMTLAAIINLILDPLLIFGIGPFPRLEIQGAAIATLFSWLVALSLSGYLLIIKHRMLERAAFDIDRMRANWSKLAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMPFIAQNLGAGQPQRAKQALLLSLKFILVFQTLLYIPLAFFAQPLASLFSTDPQVLEWLSFYILVLPCAYGPLGIVIIFATALNAYHRPMSSLVINLCRLVLLMLPLAALGSYIDGVKGLLLALPITNLLMGIACYYLAQRICEPVKATTADTL
What is the function of this protein?
Flavin adenine dinucleotide (FAD) transporter that facilitates export of flavin electron shuttles.
What are the official names of this protein?
FAD transporter, Bacterial flavin adenine dinucleotide exporter, Bacterial FAD exporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IFNL3_CHICK
Sequence: MVCYGVTIILVGTLGSLLVGAFPQVTPKKSCSLSKYQFPAPLELKAVWRMKEQFEDIMLLTNRKCNTRLFHRKWDIAELSVPDRITLVEAELDLTITVLTNPTTQRLAETCQQPLAFLTQVQEDLRDCLALEAPSHQPSGKLRHWLQKLKTAKKKETAGCLEASAILHIFQVLNDLRCAAQREDCT
What is the function of this protein?
Cytokine which plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.  Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state.  Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1.  Exhibits antiviral activity against the H5N1 influenza A virus.  Induces the expression of the antiviral MX protein in epithelial-rich tissues, such as intestine, trachea and lung.
What are the official names of this protein?
Interferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B.
What is the protein family that this protein belongs to?
Belongs to the lambda interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOEJ_SINFN
Sequence: MNSHPLMRLLRSRHTVMKLPSNAIKNDTMLPKIIPAIMAGGRGTRLWPLSRATAAKQFLKLIGEETLFQDTLKRVSDAKVYGAPLVITNEEFRFLVAEQARELGVTLSSIVLEPVPRNTAAAVAVAARIVADRFGEDALLLVLPSDHAITVDDTYKKCVRSACIAAAEGKLVTFGIQPTWPATGYGYIERGTYLGKDVHAVQCFVEKPSLEKAAALLETGNYYWNSGMFLFQAASIIAELEEHAPDVLSAVHAAVRGSTVDADFIRLAPESFSQAPSISIDYALMEKTANAAVVCSDFAWSDLGSWDAVWKNEEQNADGNVLKGNVTACNTKNSLVLSHTAHLAVQGMDGVAVIASEDAVFVGRLEEAHEIGNLVKRLAADENTARLTELHPTLIRPWGGYTTMLNGDRFQVRRLFVRPGKMLSLHKHFHRSEHWICVKGTAEVTIEDRVTILHENQSIYIPEGAIHRLGNPGKIMLELVEIQTGAYLGEDDIIRVADESRNEMPDSRRTGP
What are the official names of this protein?
Mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, GMP, GMPP.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 2 family.
Protein: CYB_CHISF
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLACLTLQLLTGFFLAVHYTANINLAFSSIIHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGSTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHILLLHEEGSSNPLGTNSDIDKIPFHPYQTYKDMLMLTIMTIMLLTIVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALTMSIMMLLTLPFTHTSKLRSMMFRPFMQLTFWTFTATFLVISWTATKPVEPPFTTISQVAALMYFLFFISNPIMGWLENKIMKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VE6_HPV28
Sequence: MDDQRPKNIFLLCRDSGISFDDLRLHCIFCAKVLTTAELSAFALRELNVVWRTGAPYGACARCLLLQGIVRRLKHWDYSLYVEGVEEETKQSIDTQQVRCYMCHKPLVKEEKDRHRNERRRLHCIAGYWRGSCQYCWLRCTVRIPQ
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RF1_STAAC
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKTVDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKEISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHLEEIIDALTLSEQTDKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.