PharMolix/UniProtQA huggingface dataset:
Protein: RLP24_DANRE
Sequence: MRIEKCYFCSAPVYPGHGMMFVRNDCKVFRFCRSKCHKNFKKKRNPRKTRWTKAFRKSAGKELTVDNSLEFEKRRNTPVKYNRELWSKTVEAMRKVESIKHKRQARFIMNRLKKGKELEKAADISEVKKNIHLIKAPHAGQAKQLEDKMVQKLAEDVEMDE
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
What are the official names of this protein?
Probable ribosome biogenesis protein RLP24, Ribosomal L24 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AMPS_BACSU
Sequence: MDSFSQKLNTYAQLAVEVGVNVQKGQYVVVNASTDVRDFVRLIVKHAYEKGAKNVTVNWQDDEVAKLKYELAPFEAFEEYPEWEAKGREELAKNGAAFISVVSSNPDLLKGIDSKRIAAFQKAAGKALHTYRQYIQSDKVSWTVVGAASAGWAHKVFPGKSEEEAIHLLWEEIFKATRVNEDNPVQAWINHDQNLHEKVDHLNERHYAALHYQAEGTDLTIKLPRKHVWAGAGSVNESGHEFMANMPTEEVFTLPQKDGVDGVVSSTKPLSYGGNIIENFTLTFENGRIVDIKAEKGEDILKELVETDEGSHYLGEVALVPYDSPISQSNILFYNTLFDENASNHLAIGSAYAFNIEGGKQMSREELVKEGLNESITHVDFMIGSKDMNIDGITADGKREPIFRNGNWAF
What is the function of this protein?
Metal-dependent exopeptidase.
What are the official names of this protein?
Aminopeptidase AmpS.
What is the protein family that this protein belongs to?
Belongs to the peptidase M29 family.
Protein: BDBD_BACCR
Sequence: MKSNKLMALGIVFSIAVLIVIGTIAYSIINDKKDKGNEMFAYSTQQSLGKDDAPVKVVEFGDFKCPACRTWDVTVLPRLKEEYIDKGKVQLYFINFPFIGKDSDLGAAAGEAIYKQDKDSFWIFYDEIYQNQKKDTEEWITEDLLLSIVKEKLPKVDVEQFKKDLHSKDIKEKVSKDSDRAQKLKVQGAPSVYVNGNLANPDFDSMKKAIDKELKK
What is the function of this protein?
May be required for disulfide bond formation in some proteins.
What are the official names of this protein?
Probable disulfide bond formation protein D, Disulfide oxidoreductase D, Thiol-disulfide oxidoreductase D.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
Protein: KYNU_BACC1
Sequence: MYTEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEETIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIHAMTDDIALILLPSVLYRSGQVLDMKRLTAEAHKRGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHCNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHVLSTAPLIGSLEIFKEAGIERLREKSLHITSYMLNLIAHELSDFEFTIGNPLEDEKRGGHIYLEHAEAARICKALKADGVIPDFRAPNGVRLAPVALYNTYEEVWKSVQILKKIMKDEEYKQFENKREVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: ENPL_RAT
Sequence: MRVLWVLGLCCVLLTFGFVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDREKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLEEDETAQEEKEEADDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPEAQVEEEPEEEPEDTTEDTTDDSEQDEEETDAGAEEEEEEQETEKEPTEKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins.  When associated with CNPY3, required for proper folding of Toll-like receptors.  Functions in endoplasmic reticulum associated degradation (ERAD).  Has ATPase activity.  May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).
What are the official names of this protein?
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.
Protein: FRDD_MYCBO
Sequence: MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ST_POVMK
Sequence: MDHQLTREESQRLMHLLKLPMEQYGNFPLMRKAFLRACKIVHPDKGGSDELSQELISLYRRLEESLPCLSTQDFIETDKVCLIEKIDYLTDWINCNFENCNKCLYCRLWNNHKSDPPFPKVWGYCLCYKCYIIWFGLEPCHFAFQSWMQIIALTPFCA
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MDTG_ESCF3
Sequence: MSPSESDDAINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEELGVTGHSALNLWSGIVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMGIVMILMGMAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPLAGGLLADHYGLRPVFFITASVLMLCFVVTLLCIKEKFQPVSKKEMLHVREVVFSLKNPRLVLSLFVTTMIIQIASGSIAPILTLYVRELAGNVGNIAFISGMIASVPGVAALLSAPRLGKLGDRIGPDKILIAALIFSVLLLIPMSFVQTPWQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTACVVLFNIIYSWNSLRRRREPQVLG
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNS1_KLULA
Sequence: MFGEGNKPTEPVPAYDAGQDPFQGPNASKNQYQGSAADYNGAPPPPASQPGNQYQFRQDQYYNLNAEGEGAPIGSFEEKFPVEGEDSKPKWNDWPFTIFFAGCVIAFIVVAAITLRAWSQNSSSQGSGVYDGANTGTLTTNSAIMLAISCIIAFVFSIIGIVLARMFPKFFIIAGILFNIIAGLATAIMYLSLKYYSAGIVFLVFTAICALFYWRMRHRIPFTVAVLKTVMDVMKSYPQTWFVTLIGSIIATAFSILFSAVIVATYMKYDDKANNPGCSTNGGSCSNAKLIGLLVLVFFCGYYIAEVIRNVIHCTVSGIFGAWYYFSKSDQGMPKWPGFGALKRSLTYSFGSICFGSLIVTIIETLKAVLRLAVDGVMGGGGADNGWMQCLALIANWIFSFLEWLARYFNHYAYVFIALYGKPYLRAAKETWYMLREKGIDALINDNLVNVALSFFTLFTCYITTLFAYLYLRYTDPNYNDNNNFTPALMAFAFVIAMEICNVITETIRSGTATFFVALGNDPEVFHLSYPERFDEIFRAYPEVLKKLSHQNV
What is the function of this protein?
Probably involved in transport through the plasma membrane.
What are the official names of this protein?
Protein PNS1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL24_CHLFF
Sequence: MKRRSVCVGDTVYVLAGNDKGKQGKVLSCLREKNKVVVEGINVRTKNIKRSQENPKGKRISIEAPIHVSNVRLSIEGAPAKISVKVTEKGRELWNKFPDGTSKLYRFVKERKG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AIM9_KLULA
Sequence: MLRIGSRCVRSVPKSSLRVSSTKIGKLFVRSVSDKPEEVFTKLSDENDPQRDAFFKYSWGTWLKNDKQEKEKRITKFSLEGLNSVIDDLYKQSIENAKRLSKSSIPPPAYLPNLTVSLPHNVKIENIGTVNPNEKIRIVSMASIHEGKHHRIYKIDTNAEKSFVLRIPYALDDENTLAYRLKSEVATMDFADLKLGLKVPKVYSFGVNALNPVRQPFILEEYIEGTLLMRSWTPLENDAEDGKSHKDKLNAVINPISKFQAKLAEVKFNAFGSLYFAKDYKTSEESAYEGETNEELKDRWRIGPSVERCLWRKKSTLNFDDRKQYLGPWDISSPLDIVKCTGLLEAENARARLGLVQAHASPEVVAEDILKDQIKTFDNLAKVAPDLINTKTTSIPKMENLLKPRLHHPDLDPMNVILKEDDDVPYLLDFEGSSIKPYILQNTPQFVAYDGPKIYDLEKDIEGYKDMEESEKAKLEFMYKRTRNQFLWEFALNENLPELISSVAPPIKVLRNPYVAAIERKSDEEYLLIEEALLQLAEVWPIFANNKLVNAAEYPLKYSEEEVKKHADALNAYHEKLISQPFAATQGWMPQDMFDNLVQGGILVKNEKGDYVISRTEDA
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIMM_SHESM
Sequence: MSSNQQPVVLGKLGSCHGIKGWLKITAYTDSVEGIFDYSPWLIKENGEWREVKVIQWRYQGKAVVAELEGVTTRERAQMLTNCEIGILPEQMNALPEDEFYWRDLIGCEVINTNGYNMGVVDQIVETGSNDVLLVKANAKDSFGKVERMLPFVPGQFILKVDIQGKQILVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_RUEPO
Sequence: MTDKTSNQMWGGRFAAGPDAIMEAINASIGFDKRLAAQDIAGSRAHAAMLAATGVITDSDAEAIREGLLTVLSEIEAGEFTFSTALEDIHMNVEARLKEIIGEPAGRLHTARSRNDQVATDFKLWVRDQFDAAEAGLLALLRALLGQAEAGADWVMPGFTHLQTAQPVTWGHHMMAYVEMFGRDLSRVRDARARMNESPLGSAALAGTSFPIDRHMTAAALGFDRPTANSLDAVSDRDFALEFLSVASICAMHLSRFAEELVIWSSAQFRFVTLSDRFSTGSSIMPQKKNPDAAELIRAKVGRIFGANTALMMVMKGLPLAYSKDMQEDKEQVFDAADNWMLALAAMEGMVRDMTANRDSLAAAAGSGFSTATDLADWLVRVLGLPFRDAHHVTGALVALAESKGCDLPDLSLDEMQSAHAAITEDVYGVLGVENSVNSRQSYGGTAPAQVRAQVARWKEMLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_PHOPR
Sequence: MIRQRTLKSIVQTTGVGLHSGRKVTLILRPAAANTGVIYRRTDLNPPVDFPADANSVRDTMLCTALVNEDGVRISTVEHLNAALAGMGIDNVIIEVDAPEIPIMDGSASPFIYLLQSAGIDTLNAPKRFLRIKKPVRIEDGDKWAELVPFNGFRLDFTIDFNHPAIDADQQRLVLDFSSQSFIKDISRARTFGFMRDIEYLQSQNLALGGSFDNAIVLDDYRILNDDGLRFDNELVTHKVLDAIGDLYMCGHNIIGEMRAYKSGHALNNQLLRAVLADQEAYEWATFQAEEVPVTFAQPGMVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: YQBT_BACSU
Sequence: MFEDQTYESIMDRMLNSISADIDKREGSVIYNALAPVAAELAKSYIWLDTVLELVFSDTAQGEFLDRRATEAGIERTAATKAVRAGEFTEGVTIPVGSRFYVDNLYFQYTADGTLECETAGEAGNANISGQNLLSLDTIPGLQKAIVKEILIPGREEEDDDSLRARYFTRVRREAVSANKAHYKQWAEEVDGVGKVKVFPLWNGDGTVKIVVTNANLEPASDILISKVKNYIDPEPGQGEGQAPIGAFVTVESAVWKEVEISAEVLPEVNSSIDQVKQEIESGVLNLFKKIAFEDNVIRLSQINNIVYNSPSVSDYADIKINGVAENLVLSAVEIPKLGQVNIIEQTR
What are the official names of this protein?
Uncharacterized protein YqbT.
What is the protein family that this protein belongs to?
Belongs to the Mu gp47/PBSX XkdT family.
Protein: YIDD_STACT
Sequence: MKKLFLGLIWVYQRFISPLTPPSCRFYPTCSNYTKEAIEVHGPIKGAWLGIKRISKCHPLHKGGFDPVPLKKDNNHQHCEHHHH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS7_LACE2
Sequence: MPRKGHTQKRDVLADPIYNNKVVTKLINNIMLDGKRGVAQKIVYGAFDRVAAKTERPAIEVFEEAMNNIMPVLEVKARRIGGATYQVPIEVKPDRRQALALRWMTTFSRARGEKTMEERLANEILDAANNTGASVKRKEDMHKMAEANKAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL9_GLOC7
Sequence: MAKRVQVVLTKNVNKLGKSGDLVEVAPGYARNYLLPQGIANIATPGILRQVEQRREKERQRLLAERQEAEARKTALQTIGRFVIRKQVGEGEAIFGTVTTQEVADVIKENTSQEIDRRGITLPEISKTGFYKAQVKLHPEVTAEIEIQVAPL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: STX18_PONAB
Sequence: MAVDITLLFRASVKTVKTRNKALGVAVGGGVDGSRDELFRRSPRPKGDFSSRAREVISHIGKLRDFLLEHRKDYINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDKKRLSKLEPEPNTKTRESTSSEKVSRSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEVRQIEGRVVEISRLQEIFTEKVLQQEAEIDSIHQLVVGATENIKEGNEDIREAIKNNAGFRVWILFFLVMCSFSLLFLDWYDS
What is the function of this protein?
Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
What are the official names of this protein?
Syntaxin-18.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: RL27_SYNJA
Sequence: MAHKKGTGSTRNGRDSNAKRLGVKCFGGELVHPGYILVRQRGTKFHPGVNVRRGGDDTLFAVATGIVTFERYGKWRKKVSVYPVEAAAQ
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: EFP_MYCPN
Sequence: MADMIEAKSLRSGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWIEFTGDKLEQVIIDKKKMTFLYKDGANYVFMDQQDYSQIEIPEKQLEWEKNFITEDSEVTIISYQSEILGVNLPELVPIEVEFAEEAVQGNTANMARKRARLVSGYELDVPQFIRTGDKIVISTIDGSYRERYNK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_CERS4
Sequence: MAEDRFPGWHGTTILAVRRGGEVVVAGDGQVSLGQTVIKGTARKVRRLSPGGHEVVAGFAGSTADAFTLLERLEKKLEAAPGQLARACVELAKDWRMDKYLRNLEAMLIVTDGETLLVLTGAGDVLEPEHDVTAIGSGGNFALAAARGLMATDLPAEEIARKAMAIAADICVYTNGNLTVERISK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN1_CAEEL
Sequence: MRSLLSFVLLALARIAISEETKSCIDIEKGFKEEFNAHKQPVCICADNGIFSTVKGFTIECESASIASVSENLASLNGTELGRLTIRDSTVNVLPQDLFENVFAKQVKLERCGLSTLQPNSFQSLGGSAELLSLRENRIKKLEKGLFTGLKSLKTLDLAMNKIQEIDVGAFEELKKVEELLLNENDIRVLKTGTFDGMKNLKKLTLQNCNLEIIQKGAFRGLNSLEQLILSNNNLENIDWTIFSALKNLRVLDLGSNKISNVEMKSFPKLEKLVLNNNTIDSMKSIKLKDLPSLVVALFDRNKIESIGDMDMFGLTRSDRIETLSLARNNLSQISPKAFQHTPNLITLLLQYNQIEELSSHSPSQVRTPFLASLKKLVTLQLSSNNLSVIRSDELPKSLSSLALDHNVISKIEARALEGMEIKRLYLHSNKLNYLYQGTFDSFSPKSVEAVDVSLNPWVCVCNDPKEWLPRWLEASEEADVAEGALGCLAIPNCGQKEGSTVMPEEEEVYRSGWITVAATILTIVTIVIMVIIAMLYFKDARYQFPLRGRRSDSDLHKLIENDPLNIASDSILVVPAMPKRNTGPKKTVRFQNF
What is the function of this protein?
Promotes the localization of myrf-1 and myrf-2 to the cell membrane (PubMed:33950834).  In association with myrf-1, promotes the synaptic remodeling of DD GABAergic motor neurons whereby new synapses form in the dorsal processes of DD neurons (PubMed:33950834).
What are the official names of this protein?
P-granule-associated novel protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane; Single-pass type I membrane protein. Note=Detected throughout the cytoplasm in germline and somatic blastomeres during embryogenesis and in germline and somatic tissue in adult hermaphrodites. Localizes to P-granules in L1 larval Z2 and Z3 germline precursor cells. Expression in P-granules is most pronounced during the meiotic stage of the germline; in mature oocytes and sperm expression switches to a cytoplasmic pattern.
Protein: SSB1_SYNY3
Sequence: MSVNSIHLVGRAGRDPEVKYFESGNVVCNFTLAVNRRTSKKDEPPDWFDLEIWGKTAEIAGNYVKKGSLIGIQGSLKFDHWEDRNSGTPRSKPVIRVNNLDLLGSKRDNAEATMNNYPEEF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: PWAP_HALLA
Sequence: YGPNLPGCPPGPYPRICARYCHSDRECKAGYYCCNTGCLNICVPKPKPGLCPAIRPGPCKGNVCSNDQDCPGNQKCCGKPGCRRCYRPEKPGSCPPRKYDAGVCVIYCVGDFDCPGNEKCCGSCPRRCEKPCFD
What is the function of this protein?
Inhibits growth of calcium carbonate crystals.  May inhibit growth of certain crystallographic planes in the mineral phase of nacre in the shell.
What are the official names of this protein?
Perlwapin.
Protein: NHAB_SACD2
Sequence: MPQSMTNAFWHNFLGHTPNWYKKTILGFLVINIVLSQVSPFLAGWALIIEFIFTLAMALKCYPLQPGGLLAIQAVLLGLTSADSVYHEVLANFKVILLLMFMVAGIYFMKDMLLFVFTKILLGIRSKLLLSLLFSFVAAVLSAFLDALTVTAVLIAVAVGFYAVYHRFASGSGHGNDHDHSADDNVHDLHREDLDTFRSFLRSLIMHGAVGTALGGVATLVGEPQNLLIAEIAGWNFIEFYLVMAPISVPALIGGLLTCAILEKTGICGYGAKLPDSVRQILVDFDKKETAKRGFGDKAQLLVQAVVAVVLVFALALHLAEVGLIGLLIIVLLTAFNGITDEHRIGHAFEEALPFTALLVVFFAVVAVIHDQHLFTPVIDYVLAMEQGAQAPMFFVANGVLSMISDNVFVATVYINEVKAAFDAGTISREHFDVLAVAINAGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGKMVIMALPYTIVLGAVGLGSVILFY
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RASH_CHICK
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPARTVETRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMNCKCVIS
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
GTPase HRas, H-Ras-1, Transforming protein p21, c-H-ras, p21ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus.
Protein: CP6B1_PAPPO
Sequence: MLYLLALVTVLAGLLHYYFTRTFNYWKKRNVAGPKPVPFFGNLKDSVLRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVLIKDFESFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKSMLPLMSQVGDRFINSIDEVSQTQPEQSIHNLVQKFTMTNIAACVFGLNLDEGMLKTLEDLDKHIFTVNYSAELDMMYPGILKKLNGSLFPKVVSKFFDNLTKNVLEMRKGTPSYQKDMIDLIQELREKKTLELSRKHENEDVKALELTDGVISAQMFIFYMAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLSEMTYLSKVFDETLRKYPVADFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENVKDRHPCAYLPFSAGPRNCLGMRFAKWQSEVCIMKVLSKYRVEPSMKSSGPFKFDPMRLFALPKGGIYVNLVRR
What is the function of this protein?
Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
What are the official names of this protein?
Cytochrome P450 6B1, CYP6B1v1/CYP6B1v2/CYP6B1v3, CYPVIB1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TRHO_RICTY
Sequence: MNERIAILSAYSFVNIIEPANLIPKFLLIGKKKYIRGTILLANEGFNCSFSGSYENVNLVLKQLIELTGSKDVNVKINYSSVHPFQKLKVRLKKEIIAMNVKDLNIEVFKGDYIEPKDWDEFITKQNVIVIDTRNEYEIDIGTFKSAINPRTETFKQFPAWVQQNQALLQGKKIAMFCTGGIRCEKSTSLLKSIGYNEVYHLKGGILQYLEDTHNKNNLWQGKCFVFDDRRAIMDDLSPAEGYWLHR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: URM1_KLULA
Sequence: MVRVIIEFLGGLDVIVKKQRQYKVDVQLDGKDEINVGDLIQWIVDNLIEHEGDVNVFLENDSIRPGILTLINDTDWELEGEKEYVLEDGDVVSFTSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.