PharMolix/UniProtQA huggingface dataset:
Protein: BRD4_DANRE
Sequence: MGDGLDAVQMSGSSSSQGQPSSQAPSSFNPNPPETSNPTRPKRQTNQLQYLLKVVLKSLWKHQFAWPFHAPVDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMPQQEVEISTTAGKGRGRGRRDPDMNMKVGPVLEPLTASPQTRGLSNLTPGPQTRGPPQGPPTLPPQPIVQIQALPPRVPPSLPTIPLHAPQLGPPFSLGPTDCNPPAPIITAVPPPTQTALPPVHIQQSAAPPILQTPISIPNKRKSQKRKADTTTPTANDQLNESSPAESKSGKTLPRRDNTRPSKLPKKEAPDSQHHWTAAPGTPSPKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEMLAPAPAPVLHPAPVKTQPVMATASSSDTSSDSSSESESSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQASKPKKKEKEKKEKKKDKHKKKAGVMPALEEILEPPPALKPQGKPKNKDPLPKKSKKLSKKEGGKSNRSMAPPGAAPPTLQPVPGLDTEEDLGLTGGAAMAGMAAGEKCKPMSYEEKRQLSLDINKLPGDKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVSSCLRKKKKPAVPEKSMEAISAVKTKGTSSDSGSSSESSSSESEDSETGMASKPKKRGRGEGKKAHHQTTAPGMPLPQVPLQPQTPALQPSIQLKQQQPQHPSPAAYMPPPVTALEPSQLLENPFDPLAHFMHLPHHANDSSSPAPPHLNAHPPGGPVSPETHPFLNQHPILPSPALHNALPQQPSRPSNRAAPLPPKPLQQSTSQQQPPPQQTLVPPQQLQPQQQQPAPPQQQHLPHHPLHAPQQMRPRPLSPPTLTPQGLLSSQPPQMLLEDDEEPVPSMSLPMYLQHLQPNRLQATPTSLMQSLQSRPQPPGQPSLLQSVQVQSHLPPPQLPVQTQVQPQQPAPHQPSPQLSQHQARHMQQLGFPQGPLQTAQTQPGQHKVSMPSTKAQQIIQQQQATQHHSPRQHKADSYNSAHLRDNPSPLMMHSPQIPQYSLVHQSPSQDKKEPQRGPSALGGIKEEKLPPSPVMRGEPFSPAMRPESHKHPDSKPTMPGHSQQRADMKPLEMSRPVIRSSEQSGPPPSMQDKEKFKQEPKTPSAPKKVQDVKFKNMGSWASLAQKSSTTPSSGLKSSSDSFEQFRRAAREKEEREKALKAQVEQAEKDRLRKEQEKLRGRDEEDSIEPPRRPLEEPRRRQEPQQVQPPPQQHQTQAQAQTLNPAQSPSASQPTQAPPQSPASSQSALDQQREMARRREQERRRREAMAATIDMNFQSDLMAIFEENLF
What is the function of this protein?
Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation.  Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure.  During interphase, plays a key role in regulating the transcription of signal-inducible genes by associating with the P-TEFb complex and recruiting it to promoters (By similarity).
What are the official names of this protein?
Bromodomain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with acetylated chromatin.
Protein: NDPA_SALPA
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NRDR_STRPM
Sequence: MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERVEELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENEVSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNNDETN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: XB31_ARATH
Sequence: MGQSMSCGSRPEHGIFASVQCGDIITIRRVMATEPSLLNQTTPYDRHSVLHVAAANGQIEILSLLLERFTNPDLLNRHKQTPLMLAAMYGRISCVKKLAEVGANILMFDSVNRRTCLHYAAYYGHANCVQAILSAAQSSPVAVHWGYARFVNIRDDKGATPLHLAARQRRPECVNVLLDSGSLVCASTSVYGSPGSTPLHLAARSGSIDCVRKLLAWGADRLQRDASGRIPYVVAMKHKHGACGALLNPSSAEPLVWPSPLKFISELNDEAKLLLEQALMEANREREKTILKGTAYSLPSPSFSDTDDNMSEVSDTELCCICFEQVCTIEVKDCGHQMCAQCTLALCCHNKPNPTTSTVTPPVCPFCRSTIACLVVAQNNNNNNEKSKSLDDVVVVDREAGDVSSSKFRKHRRSINLGEESSSFMGLSTIGSFGRITGRGSGRIAAENELMDKPIL
What is the function of this protein?
No E3 ubiquitin-protein ligase activity observed when associated with the E2 enzyme UBC8 in vitro.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase XBAT31, Ankyrin repeat domain and RING finger-containing protein XBAT31, Protein XB3 homolog 1, RING-type E3 ubiquitin transferase XB31.
Protein: PA2BC_CROOL
Sequence: HLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVH
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows edema-inducing activity and local and systemic myotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 ColTx-1, svPLA2, Basic phospholipase A2 ColTx-I, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_STUS1
Sequence: MAEITAALVKELRERTGQGMMECKKALVAAGGDIEKAIDDMRASGAIKAAKKSGNIAAEGSIAVRVEGGRGLIIEVNSQTDFLALQDDFKAFVKESLDEAFEQKLTEVAPLIASRESAREALVAKCGENVNIRRLSAVEGEVVGAYLHGHRIGVLVTLKGGDAELAKDIAMHVAASNPAVLSPADVSEELIAKEKEIFLQLNADKIAGKPENIVENMIKGRINKFLAEASLVEQPFVKDPEVKVGDLAKKAGAEIVSFVRYEVGEGIEKAEVDFAAEVAAQVAATKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
Protein: UBE4A_BOVIN
Sequence: MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQSDELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSDPSLKSGNGIPSRCVYLEEMAVDLEDQDWLDMNNVEQAVFTRLLLQDPGNHLINMTSSTTLNLSADRDAGEKHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYVDQNIHEQLVDLMVEAILGGHFESVAEFLDEVIEALILDEEVRTFPEVMIPVFDILSSRIKDLELCQILLYAYLDILLYFTKQKDMAKVFVDYIQPKDPSNGQMYQKTLLGVILNISCLLKTPGVIENHGYFLNPSRSSPQEIKVQEANIHQFMARYHEKIYQMLKNLLQLSPETKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRSSRLLTFNPTYCALKELNDEERKIKNVHMRGLDKETCLIPAVQEPKFPQNYNLVTENLVLTEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTVYLSTKTAMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQLMELTFPLPDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHMDQTPNPLVSSVFHRKRVFCNFPYASHLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILKYMWGTDTYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQIEKDRGEWDNLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLAFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFLDPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQRWLAERKQQQKEQLE
What is the function of this protein?
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases.  May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase.  Mediates 'Lys-48'-linked polyubiquitination of substrates.
What are the official names of this protein?
Ubiquitin conjugation factor E4 A, RING-type E3 ubiquitin transferase E4 A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin conjugation factor E4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKTR1_ALTAL
Sequence: MLQCAPKKNERLRGSCDFCTQSKLRCNKNKPSCRRCTIQQQPCVYSVARRTGRPPKHPRKANDCQEANGQHGEQDPVTSTPGGSCQQQSNHLLDVEGDGANFTLADASTTAQGRETAASSALDNALLVGETFGFSSLLDDPLIQSDDFLSFSLCMPPGEEEGHMASPRALNGSTGPCSPTVLSSIDVPHLPARFGFLESSVESGLHGRTGPHLVEQPDKIVPSSFSEMEKIYDEGLTFSGLDSAINAVTNNGKGEPSASGTMAAHPHSKRQCFCSTSMSKLQMLISHPTLCQKNSRARFDMTLFLEEVVFNIHRDVLQCLVCQSKSLHSLASLCICTDWVIEALRDVAQDLSSGQDNLGGFRAGLCPPKDKFSICVGRFVLDDQLRESCTRSLVKYRLRKLVPIMDTMMKLNYRGAGGALSQAIRTMVEDVRHKIESALGMMEL
What is the function of this protein?
Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AK-toxins responsible for Japanese pear black spot disease by the Japanese pear pathotype (Probable).  AK-toxins are esters of 9,10-epoxy 8-hydroxy 9-methyldecatrienoic acid (EDA) (PubMed:22846083).  On cellular level, AK-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).
What are the official names of this protein?
Transcription activator AKTR-1, AK-toxin biosynthesis regulator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSB4_YEAST
Sequence: MIMSSTMSTEAALVPNESVFDTVSSFNEDDANYSVLDLYDDDDEGDDSSTVERKEILTTRELEKAKAFTSLIMADPENFDRYGFSKKGYFISQEEYDKWWTEYNRYTERRKKKWENFLLKNKIELHNDNPLVYPARTDELSKFVRKGIPAEWRGNAWWYFAGGQRQLDANVGVYDRLKSDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQSMNFLVGLLLLFMEEEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLFYEESHFLFKVALGILKLSESEFLESKSQKLFRQYSSYTFGGSNDSDSTFKRLKNKIKTQEEADMEILQVIQNFPKRLLNPNDIFEKVLMKKKVALNGITQEKIDRGREYVAMARNRQRASSRPKERRK
What is the function of this protein?
Regulates exocytosis by functioning as a GAP for SEC4.  Also required for efficient polarization of the actin patches.
What are the official names of this protein?
GTPase-activating protein MSB4, Multicopy suppressor of bud emergence 4.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Note=Localizes to the presumptive bud site, the bud tip and the mother- bud neck.
Protein: ISDB_STAA3
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAAEETGGTNTEAQPKTEAVASPTTTSEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKEVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKKDGTQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPSVEKENDASSESGKDKTPATKPTKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: NODA_RHIEC
Sequence: MSPQVRWKVCWENELELSDHTELADFFRKTYGPTGAYNALPFEGARSWSGARPELRVIGYDAHGVAAHMGLLRRFVRVGEVDLLVCELGLWGVRPDLEGYGINSMRIVYPVLQQLGVRFAFGGVRQALRNLVLRLCRNGLATVLEGVRVRSTLADVYLNLPPTRCENVILVVFPIGCSMSDWPSGTLIERNGPEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts.
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm. Cell envelope.
Protein: AEE7_ARATH
Sequence: MAATKWRDIDDLPKIPANYTALTPLWFLDRAAVVHPTRKSVIHGSREYTWRQTYDRCRRLASALADRSIGPGSTVAIIAPNIPAMYEAHFGVPMCGAVLNCVNIRLNAPTVAFLLSHSQSSVIMVDQEFFTLAEDSLRLMEEKAGSSFKRPLLIVIGDHTCAPESLNRALSKGAIEYEDFLATGDPNYPWQPPADEWQSIALGYTSGTTASPKGVVLHHRGAYIMALSNPLIWGMQDGAVYLWTLPMFHCNGWCFPWSLAVLSGTSICLRQVTAKEVYSMIAKYKVTHFCAAPVVLNAIVNAPKEDTILPLPHTVHVMTAGAAPPPSVLFSMNQKGFRVAHTYGLSETYGPSTVCAWKPEWDSLPPETQAKLNARQGVRYTGMEQLDVIDTQTGKPVPADGKTAGEIVFRGNMVMKGYLKNPEANKETFAGGWFHSGDIAVKHPDNYIEIKDRSKDVIISGGENISSVEVENVVYHHPAVLEASVVARPDERWQESPCAFVTLKSDYEKHDQNKLAQDIMKFCREKLPAYWVPKSVVFGPLPKTATGKIQKHILRTKAKEMGPVPRSRL
What is the function of this protein?
Peroxisomal acetate/butyrate--CoA ligase that is probably involved in the activation of exogenous acetate for entry into the glyoxylate cycle.  May play a role to prevent carbon loss from peroxisomes during lipid mobilization.  In vitro, is active with both acetate and butyrate.
What are the official names of this protein?
Acetate/butyrate--CoA ligase AAE7, peroxisomal, AMP-binding protein 7, AtAMPBP7, Acetyl-CoA synthetase, Acyl-activating enzyme 7, Butyryl-CoA synthetase, Protein ACETATE NON-UTILIZING 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: AF1_GRARO
Sequence: YCQKWLWTCDSERKCCEDMVCRLWCKKRL
What is the function of this protein?
Inhibits the voltage-gated sodium channels Nav1. 1/SCN1A (IC(50)=360 nM), Nav1. 2/SCN2A (IC(50)=600 nM), Nav1. 3/SCN3A (IC(50)=1280), Nav1. 4/SCN4A (IC(50)=330 nM), Nav1. 6/SCN8A (IC(50)=1200 nM), Nav1. 7/SCN9A (IC(50)=1-40 nM), and voltage-gated potassium channels Kv11. 1/KCNH2 (IC(50)=4. 8 uM) (PubMed:19955179, PubMed:30661758, PubMed:31234412).  Induces analgesia in mammals (Ref. 1).  This analgesia is mediated by a non-opioid receptor related mechanism (Ref. 1).
What are the official names of this protein?
Beta-theraphotoxin-Gr1b, Beta-TRTX-Gr1b, GsAF 1, GsAf1, GsAF I, GsAFI.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNX4_ASPFU
Sequence: MDQHDDFDSVSWRQDPESDISRPTTSGTDADESLEYNRDTNGKRRMSSVHEDPPQAGPLADAVDLAGIGDGVLECRVDSPLKENDGTKDAYISYLVTTHTDFKSFQKPDFAVRRRFTDFYFLYKTLYREYPACAVPPLPEKHKMEYVTGDRFGPEFTSRRAWSLHRFLKRLTLHPVLRRAPLLAIFLESPDWNAHMRLHSTRTSTGNSDGSGTGIFDNFTDTFVNAFTKVHKPDRRFIEVKEKADKLDEDLNHVEKIVARVARRESDLEADYNDLATQFRKLVPLEPDVEVPLQIFAASVEETARGFKMLKDHTDQNYLGSLRDMEAYIVSVKALLKTREQKQLDFEALVDYRNKAVAERDSLAANPSSYYASNPLTSSPASFIRSKMEDMRGVDHEQSRRERVRKLELRIDELTREVESAKTTSEMFDEEVVREVADFERIKAVEFRDTLGALAEKHIDFFQGAINTWERFVAEMEGDLDNDPEMSEHGRGGGVAA
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells.  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy.
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures. Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures.
Protein: RNFH_YERPB
Sequence: MPDIRVEVVYALSERQYLRTVSLVVGSTVEDAIKASGLLELRPDIDLEKNKVGIYSRPVKLGDKLNDGDRVEIYRPLIADPKELRRQRAEQAKK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RIDA_ECOLI
Sequence: MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPADVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATFPARSCVEVARLPKDVKIEIEAIAVRR
What is the function of this protein?
Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell.  It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia.  It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities.  Involved in the isoleucine biosynthesis.
What are the official names of this protein?
2-iminobutanoate/2-iminopropanoate deaminase, Enamine/imine deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_SHISS
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ACP1_CUPLA
Sequence: MASAAAGASICIKSASFSPLAPGRISSLRSVSLPVSRKSFPSLKSSKSSFALRVSCQAKPETVAKVCGIVKKQLALPDDSEVNGLSKFSALGADSLDTVEIVMGLEEEFGISVEEESAQSIQTVQDAADLIEKLMEKKGH
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 1, chloroplastic, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYCE1_BOVIN
Sequence: MAGRPGSSNAEAAGAVGPTDEARGQAESSQKIEDLMEMVKKLQKVGSLEPRVEVLINRINEVQQAKKKASEELGDARTVWETLQKELDSLSGEKVRLKEILSKKQETLRVLRLHCQDKENEAQRKQTMLQECKERISALNSQIEQEKNKQRQLRLDFEEQLEDLMGQYKDLWEFHKPERLALEISTLDSGKEQLLKEEKLVEAKLEDVKHRLCSQFGAKGHTINEGLFLRSPEAAAVVHLFEEENRKAQELLEAAAQRQEQLQQKCQQLQQKRQRLKEELEKLGVQVLAQAQSKQEEEAGLGEAANPKPLGVSEEKDQEPSTK
What is the function of this protein?
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.  Requires SYCP1 in order to be incorporated into the central element.  May have a role in the synaptonemal complex assembly, stabilization and recombination.
What are the official names of this protein?
Synaptonemal complex central element protein 1.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements.
Protein: ATPL_HAEIN
Sequence: METVITATIIGASILLAFAALGTAIGFAILGGKFLESSARQPELASSLQTKMFIVAGLLDAIAMIAVGISLLFIFANPFIGLLN
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NOAT_STRMU
Sequence: MTKLSRRVLEMEESVTLATSARAKTLKAQGRDVLELSLGQPDFVTPKNIQEAAMKSIRDGRASFYTIASGLPELKDAISQYFEKFYGYSVERKQIVVGTGAKFILYALFAAVINPKDEVIIPTPFWVSYADQIKMNDGVPVFIRTSEENHFKATVEQLEAARTNKTKMIVLNSPSNPTGMIYSKKELEAIGNWAVKHDILILSDDIYGRLVYNGARFTPISTISQPICQQTIVINGVSKTYSMTGWRVGYAVGDPEIIGAMSKIVSQTTSNLTTAAQYAAIEALIGNQDTVEVMRQAFEERLNTIYPLLAKVPGFHVVKPEGAFYFFPNVKKAMEMKGYTDVTEFTTALLEETGVALVTGAGFGAPENVRLSYATDMVTLKEAINRIQAFMEK
What is the function of this protein?
Catalyzes the transamination reaction between L-asparagine and 2-oxoglutarate to produce L-glutamate and 2-oxosuccinamate (PubMed:22569339).  Is not active with pyruvate as amine acceptor (PubMed:22569339).  May also use other amino acids as substrates.
What are the official names of this protein?
Asparagine--oxo-acid transaminase, Asparagine:2-oxoglutarate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: CDK9_CHICK
Sequence: MAKQYDMVECPFCDEVSKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNTHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGGGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQGRNPAATNQTEFDRVF
What is the function of this protein?
Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP.  The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 9, Cell division protein kinase 9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAG_THEAC
Sequence: MVMLISLSFKKVIWMNVDPNLTKYMIKAKIYTDGVVEKPDVVGAIFGQTEGLLGDDLDLRDLQKSGKIGRIEVEIDSKKGRTEGYALIPSGLDQVETAILAAALETIDRIGPCKAKVEIANVEDVRVQKRQKIIERAKKIYQDMNSKGDDLSESLVKSVREEVEKSEIISYGEEKLPAGPAINDSDSIIVVEGRNDVLNLLKYGIKNTIAVQGTNIPETVKKLSKERTVTVFLDGDRGGDLILKEMLQVAEADFVARAPPGTEVEELTYKQIVKALRYKTPIDQYLSMHGMNDELKEYSQRNNLVFGSQPNNNHEAKAEVIEEPPEQPPKNEEIREEQSQQVTVQKEGFLDLLNPHEVSKRIEALAQLKMTEVYDSNGERIFSFPVSEAVERISQDPRGNTIVTGGIISQRLIDVSYNAGIKNIYGLKLGHITKKPVDINVIAWERSL
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: GEFM_DICDI
Sequence: MWQKPSLTKSMMNEVSSNSPKSPTLTSSPSTQSFANRVLPGRNLDGGGGGSNRLIFGGSGGGSGGGSLPSSPVSSPVNPFNLNGGGGGKSSRRRGVTVAAGSEQVETRRKILLGNSRPFRRRARSMEILNSWDFIPYQKKPSDDEQGQVDQYIQGENDEDLTSYESYITNNNTTTTTNTNNSNNNNSNNDGSGSGSGAGGSFIGTTTSAKTTSTTSTSAATTTTTTTTSSSSSSPSSSSPSSTSPTIASNNDNNNKIEPPQPSKIANSVPPLTLSQSQTQQQQQQKVKPPPPSPRFSTNSSGSQSPPVPPRSSKSLGLSNDFSISLSSSMSSNSLLISGSINTLPTSSSSSSSVGGSGASAASASISSSSSLSSSSLSVSKLIYENNEENKFVVVSGPKDQLVEYLCNKNKLDFSFVNSFILSFRYFIEPEELFNHLMVKYETKVQTTSSIKVSKQFEEIQDRIRQNILIIISVWVDCNYSDFEDNLSLHKRLFKLVQDTPHAVFLRDSIDRQKVSKIPILDLYEKLKDELLLSLSPRGSLSGSGGISNNNNGSDLKNSNNGNNSSNNNNSSSNSSSSSSSSDIKNIKNSFFSLTTMMDWLMNHLSIGYATADSILKKLFKLKVIGSLGSGGGFTNISSSHTNSNSKSSKEELYFFTSTKSIINKEIYSRSFMDYSPQDIAKQLTLIEFKLFQSVKMKELYHKSWTISKSKFENSPNIMSLITMSNKIANWVATEVVTTPHPKKRVEVLKRFISVAEHCKKINNFNTLMEVISGLSNSAVSRLKETWKSLPTRYVNSFNSLQNFLKTDENWKSYRQTLKTKETPCLPYLGLFLQDINFIEDGNSNLSSENDWVNFKKMNLLTSVFTEIQYFQRHPYFSFSTHQNIQTYFEKDIVILPEKELYAFSKFIESPSNPLFRLSKSKNQSIFNI
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Ras guanine nucleotide exchange factor M, RasGEF domain-containing protein M.