PharMolix/UniProtQA huggingface dataset:
Protein: ENGB_RICAE
Sequence: MTTQKIVPTKSTDGSKLFRHQAKFVAGAMNINQIPNFSLPEIAFVGKSNVGKSSLINTICSNKNLAKVSNTPGRTRQINFFNLADKLIIVDLPGYGFANVPISVKEQWGVLISYYLRNSYNLRLVNLLIDSRRGIKENDKKVADLLLANKREFQIIFTKSDKVTDHKNLHDEAQNFLATLNYSCNVMYVSNRSKEGARELKASLAKCIKPQK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PIMT_ECOSM
Sequence: MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRR1_YEAST
Sequence: MDEYSSIYSQPKTPRLKQEGFPDSIGDQHEKALIDENGEEDKKMASTEGTTGDSRSTPLTVSIPTFENVQALPTPMTYTPLSPGNLSMSPIDQSSLNIPKRRSHARLLDDMLSVTQPNQRVVSELIAPANLSPQRVVSLPTVTEEALVNDSVDSDNYTKEPYFPESSSSTEKCDDDIFQGFLLDHWDRPLLWKKVRPIGSGNFSTVLLYELMDQSNPKLKQVAVKRLKYPEELSNVEQINTSLRYKETLSRLENSLTRELQVLKSLNHPCIVKLLGINNPIFVTSKKPLCDLIIKTPRALPPCDMIMSYCPAGDLLAAVMARNGRLEAWLIQRIFTEVVLAVKYLHENSIIHRDLKLENILLKYSFDDINSFRDSPIYCKQNFIELADFGLCKKIENNEMCTARCGSEDYVSPEILMGVPYDGHLSDTWALGVILYSLFEDRLPFDPPPNASARQRSRATSHRIARFDWRWYRLSDYKTNVGKQIVENTLTRKNQRWSINEIYESPFVKTIADTLSFS
What is the function of this protein?
Protein kinase that functions as regulator in the pheromone-induced mating pathway downstream of mitogen-activated protein kinase (MAPK) FUS3.  Diminishes transcriptional induction of genes in response to pheromone signaling.
What are the official names of this protein?
Serine/threonine-protein kinase PRR1, Pheromone response regulator 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME32_ARATH
Sequence: MAKFRQMGSSIFFLFLIIISLCSAHKEAFSSTDLVQMECLRVPPLEFAEAAKTVVDAITKAVAIVSKFDKKAGKSRVSNAIVDCVDLLDSAAEELSWIISASQSPNGKDNSTGDVGSDLRTWISAALSNQDTCLDGFEGTNGIIKKIVAGGLSKVGTTVRNLLTMVHSPPSKPKPKPIKAQTMTKAHSGFSKFPSWVKPGDRKLLQTDNITVADAVVAADGTGNFTTISDAVLAAPDYSTKRYVIHVKRGVYVENVEIKKKKWNIMMVGDGIDATVITGNRSFIDGWTTFRSATFAVSGRGFIARDITFQNTAGPEKHQAVAIRSDTDLGVFYRCAMRGYQDTLYAHSMRQFFRECIITGTVDFIFGDATAVFQSCQIKAKQGLPNQKNSITAQGRKDPNEPTGFTIQFSNIAADTDLLLNLNTTATYLGRPWKLYSRTVFMQNYMSDAINPVGWLEWNGNFALDTLYYGEYMNSGPGASLDRRVKWPGYHVLNTSAEANNFTVSQLIQGNLWLPSTGITFIAGLVS
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 32.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: AZOR_LEPCP
Sequence: MKILQVNSSARNFANGVGSVSSQLAGELVARLRDGEPTASVVVRDLARTPHPVLDEAALQALFTPADQRTPAQAERVALDDALIAEIQAADVVVIAAPMFNFGITAQLKNWIDAIARAKVTFQYTANGPEGLLKGKRVHVVLTRGGVYRDQASDNQVPYLRQVLGFLGMTDVEFIYAERQGMGPEASAQGVAEAREQIAALLQLGTATA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: TRMD_STRT2
Sequence: MKIDILTLFPDMFAPLEHSIVGKAKDKGILEINYHNFRDNAEKARHVDDEPYGGGQGMLLRAQPIFDTFDKLNVTKPRVILLDPAGRTFNQAYAEELAQEEELVFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPEVLGKEASHKDDSFSSGLLEFPQYTRPAEFRGMKVPDVLLSGHHVNIRRWRMEQSLRKTWERRPDLLENYDFTDEERQILEEIKSEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_LACSA
Sequence: MVTIQADEISNIIRERIEQYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESTNVGVVLMGDGLLIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISSSEYRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGKNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTSIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLGVEEQVLTIYTGTNGYLDSLEIGQVRKFLVELRTYLKTNKPQFQEIISSTKTFTEEAEAILKEAIKEQRERFILQEQAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y2729_PELTS
Sequence: MFTPKLVIVTGLSGAGKTQALRSLEDLGFFCVDNLPPALIAKFAELCAQAASRINNIALGVDIRGGEFFNALFQVLSDIDAQGIQYEILFLEASDETLVRRFKESRRPHPLSTHGEILDVIREERNRLRDLRGMANKIIDTSNMEVKQLKEEIAAIFGDSTVASRLHITVVSFGFKYGIPLDSDLVIDVRFLPNPYYQPSLRVLTGNDPAVRDFVFSSPVTEEFMKKFTDLIKFLIPHYIKEGKTTLMIAIGCTGGMHRSVALAGRLGEILREKDFRVTVRHRDINRV
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein PTH_2729.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NAGZ_ECODH
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGX49_CENSC
Sequence: DRDSCVDKSRCGKYGYYGQCDDCCKKAGDRAGTCVYYKCKCNP
What is the function of this protein?
Reversibly blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 4.9, CsErgTx3, CsErg3, ErgTx3, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UNC86_CAEEL
Sequence: MQNTAPVPTTTTASKMQPFNNSLFGSFDDPILNARAAQVALADIDVKNVPQLTNPLMRPHDMFSYSNYFSGIHDTSAATNIYQGLPSSSEPFDASVVVPTSSDDQMTPLQQVMAMQQSYGAPPPFQYNMTHPFSTTSIASSNNLARYPIAPPTSDMDTDPRQLETFAEHFKQRRIKLGVTQADVGKALAHLKMPGVGSLSQSTICRFESLTLSHNNMVALKPILHSWLEKAEEAMKQKDTIGDINGILPNTDKKRKRTSIAAPEKRELEQFFKQQPRPSGERIASIADRLDLKKNVVRVWFCNQRQKQKRDFRSQFRARSAAAVMGPRVMPVLNGNNSNNNLKQGQTTYNGLPGFFD
What is the function of this protein?
Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions (PubMed:7237544, PubMed:2257628, PubMed:26096732, PubMed:10899123).  Involved in sensory neuron production and function (PubMed:1361171, PubMed:9735371, PubMed:10899123, PubMed:26096732).  Binds both alone and with mec-3 to the mec-3 promoter to initiate and maintain mec-3 expression which is required for sensory neuron differentiation (PubMed:1361171, PubMed:9735371).  In addition, binds both alone and with mec-3 to the promoters of mec-4 and mec-7 which act to regulate sensory neuron function (PubMed:9735371, PubMed:10899123).  Involved in determining the identity of the serotonergic NSM neurons and the cholinergic IL2 sensory and URA motor neurons (PubMed:24353061).  Promotes expression of the cfi-1 transcription factor in the URA and IL2 neurons which in turn activates normal URA and IL2 gene expression (PubMed:24353061, PubMed:11959845).  Required to determine the identity of BDU sensory neurons in concert with transcription factor unc-86, regulating expression of a number of genes, including transcription factors ceh-14 and ahr-1, neuropeptides flp-10, nlp-1 and nlp-15, and tyramine receptor-encoding ser-2 (PubMed:26096732).  Regulates expression of a number of genes in NSM neurons including bas-1, cat-1, dop-3, mgl-3, nlp-13, scd-2 and ptps-1 (PubMed:24353061).  In the IL2 neurons, required for expression of cho-1, gcy-19, klp-6, lag-2, unc-5 and unc-17 (PubMed:24353061).  Promotes expression of pkd-2 in the male-specific CEM head neurons (PubMed:11959845).  Required for dauer-specific branching of IL2Q neurons and nictation behavior (PubMed:23932402).  Controls both the timing and direction of axon outgrowth in HSN neurons (PubMed:21656875).  Plays a role in serotonin production by regulating expression of the tryptophan hydrolase tph-1 which catalyzes serotonin synthesis, in the AIM, NSM, HSN and RIH neurons (PubMed:12135927).  Involved in regulation of lin-11 expression in the AIZ interneurons, the major interneurons of the olfactory pathway, and is required for odortaxis behavior (PubMed:12883006).  Involved in neurite pruning between AIM neurons during larval development by regulating the expression of transcription factor mbr-1 (PubMed:16139210).  Required for correct localization of unc-40 (PubMed:24353061).
What are the official names of this protein?
Transcription factor unc-86, Uncoordinated protein 86.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
Protein: LEU3B_ASPNG
Sequence: MSGTRAYNILVLPGDGIGPEVMAEAIKVLRTFNSSSMQFHLQEELIGGISIDTHGHSVTQPVKDAAVAADAVLFAAVGGSKVDHIRRGLDGPEGGLLQVRKAMDIYANLRPCSVDVPSREIARDFSPFRQEVIEGVDFVVVRENCGGAYFGKKVEEENYAMDEWGYSTTEIQRIARLAAELALRHDPPWPVISLDKANVLASSRLWRRVVENTISVEYPQVKLVHQLADSASLIMATDPRVLNGVILADNTFGDMLSDQAGSLIGTLGVLPSASLDGLPHPGKQEKVRGLYEPTHGSAPTIAGKNIANPTAMILCVSLMFRYSFNMENEARQIEDAVRAVLDRGLRTPDLGGNSSTQEFGDAVVAALQGKY
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase B, 3-IPM-DH B, IMDH B, Beta-IPM dehydrogenase B.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_THEP1
Sequence: MKRTYQPSRRKRKRTHGFLARKRTPGGRRVLKNRRRKGRWRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL4_CLOK1
Sequence: MPIVGLFNKEGQKITDFELSDKVFGVEVNQYVMHQVVVALLANKRQGTQSAKTRAEVSGGGIKPWRQKGTGRARQGSIRSPQWIHGGVVFAVKPRSYRISVPKSARRLAMKSALSSKVEENQIVVLESLEMDTPKTKEVVKILDAFEAKKTLIVTAESNQNVYKSARNIQGVSVIPVNNLNVYDLLKFDKLIITKDAVSKIEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GDPD2_ARATH
Sequence: MALRTVLVSDVPSLPDSVYGLSEGLELSKPTSFRLPGFSVIGHRGIGMNVLQSSDRRARGVKENSILSFNSAAKYPIDFIEFDVQVTKDDCPVIFHDDFIYSEENGIVNESRVTDLSLSEFLLYGPQKETEKIGKTLMRKSKEGKVLKWDVDLDDSLCTLQEAFEQVEQTLGFNIELKFDDQTVYEREFLVHILRSVLQVVSNYAKDRPVIFSSFQPDAAKLVRELQSTYPVFFLTDAGNEIHNDERRNSLEEAIQVCLEGGLQGIVSEVKGVFRNPAAISKIKESNLSLLTYGKLNNVGEAVYMQYVMGIDGVIVDFVEEIIESTTRMMIRPPPSSSPLPSPSKDDDVAITRPEFSQKEISFLLKLLSQLIQH
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase GDPD2, Glycerophosphodiester phosphodiesterase 2, AtGDPD2.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: PUUD_ECO57
Sequence: MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIALPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPERDLLSMALINAALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQVEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALGVQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL
What is the function of this protein?
Involved in the breakdown of putrescine via hydrolysis of the gamma-glutamyl linkage of gamma-glutamyl-gamma-aminobutyrate.
What are the official names of this protein?
Gamma-glutamyl-gamma-aminobutyrate hydrolase, Gamma-Glu-GABA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
Protein: HAM1_CAEEL
Sequence: MTYLAVVLNGPKAKNGRKVFDSFLEQNRQMFWNRELTSACESITYMGFMRPGTLFVSGPASQLTVLKDAWARRILKPAMGYTITSLGDLGAIQQVEQMHFVPLGDVICDAVAQLNRQGLAATEQAIRQYVARHCPHVAPPGIEMVRQTITSLLSTGFVYKMADHYFVSVPTNSPMRPPAKAATKTTKTTVECQTGASMMCPQQTSTSSDEHVIEPAKKDHKKCQNSNRRSIFARLFSRGMKPQTIMPSASPIHVGGPPTPPPAAMLPTKNKYPTYHHDLNEECQRKARRRNHPRRGETQKLLSSSSECLKYYPVDMPETRPTRRRARMASPLRSSTPNNSDSAYSISPPHTDSNEEAGSISDSEINHTYININKFRRQNFDSTQFEDLTGATATTSEEPEILGRHIRGVLISNL
What is the function of this protein?
Probable transcription factor (PubMed:23946438).  Required for asymmetric cell division in neuroblasts, perhaps acting by regulating spindle positioning and myosin polarization, and thus the position of the cleavage plane (PubMed:3200316, PubMed:18505863, PubMed:8951066, PubMed:26703426, PubMed:15979607, PubMed:23946438).  Required to produce daughter cell size asymmetry in neuroblasts undergoing asymmetric cell division, usually giving rise to one precursor cell and one apoptotic cell (PubMed:29668718, PubMed:15979607, PubMed:23946438).  Positively modulates expression of the serine/threonine kinase pig-1/MELK during asymmetric division of the Q. a neuroblast (PubMed:23946438).  Plays a role in neural fate specification in several dopaminergic lineages, including the hermaphrodite-specific neuron (HSN)/phasmid neuron (PHB), acting in concert with the kinase, ham-1, and the T-box protein tbx-2 and the homeobox protein egl-5 (PubMed:3200316, PubMed:18505863, PubMed:8951066, PubMed:28659600, PubMed:23946438).
What are the official names of this protein?
Stork-head box protein ham-1, HSN abnormal migration 1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Nucleus. Cytoplasm. Note=Distributed asymmetrically in the cell cortex in some embryonic cells, including the hermaphrodite-specific neuron (HSN)/phasmid neuron (PHB) neuroblast (PubMed:15979607, PubMed:26703426). Localized to nucleus during interphase and evenly distributed in the cytoplasm of dividing Q.a and Q.p neuroblasts (PubMed:23946438).
Protein: MBL2_TRACR
Sequence: MSLFPSLPLLLLCVVATSYSETVNCEDSQKICPAVIACNSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDCDSSLAASERKALQTEMAHIKKWLTFSLGRQVGNKFFLTNGEMMTFDKVKALCAKFQASVATPSNAAENRAIQNLIKEEAFLGITDENTEGQFVDLIGNRLTYTNWNNGEPNNADSDEDCVLLLKNGKWNDVPCSSSHLALCEFPI
What is the function of this protein?
Calcium-dependent lectin involved in innate immune defense.  Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.  Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
What are the official names of this protein?
Mannose-binding protein C, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin.
What are the subcellular locations of this protein?
Secreted.
Protein: NUDC_SALPB
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: CSCR_SHIFL
Sequence: MASLKDVARLAGVSMMTVSRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKSGKPDFDVLICGNDRAAFVAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGREGGRVTRIPCPLLIRCST
What is the function of this protein?
Repressor for the csc operon.  Binds D-fructose as an inducer (By similarity).
What are the official names of this protein?
Sucrose operon repressor, Csc operon regulatory protein.
Protein: IFNT3_BOVIN
Sequence: CYLSEDHMLGARENLRLLARMNRLSPHPCLQDRKDFGLPQEMVEGSQLQKDQAISVLHEMLQQCFNLFHIEHSSAAWNTTLLEQLCTGLQQQLEDLDACLGPVMGEKDSDMGRMGPILTVKKYFQDIHVYLKEKEYSDCAWEIIRVEMMRALSSSTTLQKRLRKMGGDLNSL
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible.
What are the official names of this protein?
Interferon tau-3, IFN-tau-3, Antiluteolysin, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: SEPF_FRAAA
Sequence: MGLGRRAMVYLGLAEEDEDYLDDDDYDDGRAVGHDDRRAMHEPVPMDRTVRRIDAREEPVAMPRRPPVEPLRPAGPVPMRRVMPVEETHPYRITTLQPRSYNEARQIGEEFRDGTPVIMNLTDMDDVDAKRLVDFAAGLIFGLRGDIEKVTNKVFLLSPHNVEVTETDKRRIREGGFYNQS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PURA_CORDI
Sequence: MAAIVIVGAQWGDEGKGKATDILGGQVDYVVKPNGGNNAGHTVVVGGEKYELKLLPAGVLSENATPILGNGVVINLEALFEEMDGLIARGCDASRLRISSNAHLVAPYHQILDRVQERFLGKRAIGTTGRGIGPTYADKVSRVGIRVQDVFDESILRQKIESALNVKNQTLVKMYNRKAIVAEEMVQYFLGYVERLRPMVIEAELELNRGLDAGKHVLMEGGQATMLDVDHGTYPFVTSSNPTAGGACVGSGIGPTRITSSLGIIKAYTTRVGAGPFPTELFDKWGEFLQTTGGEVGVNTGRKRRCGWYDSVVARYASRVNGFTDLFLTKLDVLTGIGEIPICVAYDVDGVRHDEMPMTQSDFHHATPIYETMPAWDEDITGCKTFDDLPEKAQAYVRRLEELSGCRISYIGVGPGRDQTIVCHDVMEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S1A1_NAJSP
Sequence: MKTLLLTLLVVTIVCLDLGYTLECHNQQSSETPTTTGCSGGETNCYKKSWRDHRGYRIERGCGCPSVKKGIEINCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Alpha-neurotoxin NTX-1, NTX1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NQOR_CUPMC
Sequence: MSKVLVLYYSTYGHVEALAEAVAEGARATGATVDVKRVPETVPAAVAEASHFKVDQKAPVATVEDLANYDAIVVGTPTRFGRISSQMAAFLDQAGGLWMRGVLNGKVGGAFTSTATQHGGQEATLFSIIANLLHFGMTIVGLPYSHQGQMTLDEIVGGSPYGATTIAGGQGQRQPSAIELEGARHQGELIAKTANKLFG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: HXD10_SAGLB
Sequence: MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPEPCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPANGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFX
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.