PharMolix/UniProtQA huggingface dataset:
Protein: DHX57_HUMAN
Sequence: MSSSVRRKGKPGKGGGKGSSRGGRGGRSHASKSHGSGGGGGGGGGGGGGNRKASSRIWDDGDDFCIFSESRRPSRPSNSNISKGESRPKWKPKAKVPLQTLHMTSENQEKVKALLRDLQEQDADAGSERGLSGEEEDDEPDCCNDERYWPAGQEPSLVPDLDPLEYAGLASVEPYVPEFTVSPFAVQKLSRYGFNTERCQAVLRMCDGDVGASLEHLLTQCFSETFGERMKISEAVNQISLDECMEQRQEEAFALKSICGEKFIERIQNRVWTIGLELEYLTSRFRKSKPKESTKNVQENSLEICKFYLKGNCKFGSKCRFKHEVPPNQIVGRIERSVDDSHLNAIEDASFLYELEIRFSKDHKYPYQAPLVAFYSTNENLPLACRLHISEFLYDKALTFAETSEPVVYSLITLLEEESEIVKLLTNTHHKYSDPPVNFLPVPSRTRINNPACHKTVIPNNSFVSNQIPEVEKASESEESDEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAENGKICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Putative ATP-dependent RNA helicase DHX57, DEAH box protein 57.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: PSRP_ECOSM
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: MIC19_SCHPO
Sequence: MGNQQSQPEFVLRAPTEFSEKFVRHLQESTETDTSRYMDMENYIQKRVQDELKQLQLRQKKAIDAIQEEEWKSNAKTIKDSQGSLDSNLLSAEFRSFQEKLEKQSSINDKELKIKLKEVESIRSDLLKCMSEHPDKSLICHPLAEKFAILASKLHNPKVGSV
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit mic19.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: SYV_STRMK
Sequence: MTQLASSYDPKSFETDLYEAWEKAGHFKPSGTGEPYTILLPPPNVTGTLHMGHAFQQTLMDALVRYHRMRGYDTLWQVGTDHAGIATEMVVSRNLALEGKGETRDSLGREGFIGKVWEWKQQSGDTIERQMRRLGTSADWSRSTFTMDPQPSAAVNEAFVRWYEQGLIYRGQRLVNWDPVLKTAISDLEVESAEEDGFLWSIAYTLDEGLSYEHVERDADGVETLRETRDYLVVATTRPETLLGDTAVMVHPEDKRYAHLIGKSVVLPLTGRRVPVIADDYVDRAFGTGVVKVTPAHDFNDYEVGVRHSLPMINLFTPVAALNENAPERFQGLDRYAARKAVLAELEDLGILVETKAHKLQVPRGDRTGQVIEPYLTDQWFVKMDDLAKRGLELVEDGSISFVPPNWINTYRHWMNNIQDWCISRQLWWGHRIPAWFDEATGSCYVGRSEEEVRAKHNLGSDVVLNQESDVLETWFSSQLWPFSTLGWPNEQAMAERGFDRYLPSSVLITGFDIIFFWVARMIMATDNLVGKIPFKDVYFTGLIRDGQGQKMSKSKGNVLDPLDIIDGITIDDLVAKRTGGLMQPKMVEKIEKATRKEFPDGIAAHGADALRFTIAALATHGRDIKFDMNRAEGYKNFCNKLWNASRFALMNTEGAAFTGVPRPRTDAERWILARLAATTAEAQGHFAAYRFDLLAQCLYEFAWNAFCDWFLELSKPALNGADAADAESTRHTLLYVLEALLRLLHPLTPFITEQLWQQLAPRLGLAETTLSLRPYPTAAEFEGDFAQAEADVEWLKAVISAVRRVRSELNVAPSKLVPLRLQAGLEQDRVRIERFSASLSFLLKLDSIQWLAEGESAPPAAAAIVGELKLLVPLEGLVDLDAERVRLDKEIARVEAEKEKSETKLAKFTDKVPPAVVEQERVRLADWNTQLAGLREQRAKL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECNB_ECO57
Sequence: MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAATKAQQ
What is the function of this protein?
Plays a role in the bacteriolysis.  Is activated under conditions of high osmolarity by the factor sigma S.  Entericidin A functions as an antidote (By similarity).
What are the official names of this protein?
Entericidin B.
What is the protein family that this protein belongs to?
Belongs to the EcnA/EcnB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RIPR2_DANRE
Sequence: MAFPDITEDDLNELMREEAEDVFDDDGVSSRFPDIMAAGTHSPGGPNGIIRSQSFAGFSTLQERRSRCNSFMGNSAVQKKPISKPRKPHLSGHKSSSSSSSSREPQPKRVEEVYSALKQGLDEYLEVHQTELDKLTSLMKDMKRNSRLGVLYDLDKQIKTIERYMRRLEFHISKVDELYEGFCIQRRLRDGASKMKQAFTASPSTKGTRESLAEVNRRYKEYTENMSTFEGELENLLGEFHIKMKGLAGFARLCPGDQYEIFMRYGRQRWKLKGKIEGNSKQSWDGEEMIFMPLISDLINIKVTELKGLATHVLVGSVICETKDLFTAMPQVVAVDVNDLGTIKLNLEVAWFPFDVEDLTLSSGNVSKATALQRRVSVYSQGTPETPTFQDTSFFKWQPRRWEGQRLSFLHTLRETLIEKLRRSRSFGDLAALRPRSRSSLEVYSTLPDDVFENGGCGVAECKRLSFTFSDTSTSSPVPVQSNPEITVTPPETDPSSEPPPTSEEQLVEEECVEEDCGSISVSVSVSDPDLEWDQVETQGPETGSVALSLCSESQLSAVGPEDVVFLEPNVSDEALELKPVELDGEEGSLTRQLVRRLTSSDMLPETSALSWAGENSRTFMESSLEEVIQSLLLRLESLGQRCGELQDLEQEVMRLEDLLKCRVHAHRSRSSSLSLTVESALESFDFLNTSDFDDDDTGDDAGTLSRAVFFDMESERMGSGQHPEARGHLSEALTEDTGVGNSVAGSPLPLTTGNENLDVAVVIHLQYCNHLIQLLTSGGSQLQHKTYLHKLATQTLLLEELSERNFDRPSSCTSVPDVLPGLVERPALMSLWSDCSGGLFHTTLDRVLKHMHLSFALGLQQVLPHSPDSVIKMVVNEMMDRSELASSSTSPAQDVITVFQFHRYIVEHCITDMEQHLLDLAKEVMLEEALSCGDPERSLKELKKVSITCLQPRSQTLLAVAGLLTTDDPEVMKATTDFLSSAASHQPFRSKAVDCYTQALSESELHTQRAACAALSCLQAVESIDAVILLCDSVDEELRQIAIETLLTFGEDGRLAYEQLDTVPREMVRLGTRRGNAVTTSF
What is the function of this protein?
Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (By similarity).  Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation (PubMed:24958875).  Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration.  Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion.  Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear.  Plays a role for maintaining the structural organization of the basal domain of stereocilia.  Involved in mechanosensory hair cell function (By similarity).  Required for normal hearing (PubMed:24958875).
What are the official names of this protein?
Rho family-interacting cell polarization regulator 2.
What is the protein family that this protein belongs to?
Belongs to the RIPOR family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, filopodium. Apical cell membrane. Cell projection, stereocilium. Cell projection, stereocilium membrane.
Protein: A375_VACCW
Sequence: MDSFSSLFMKLCCISTDKTGSKKSDKKNKNKIKDYMEHDYYKITIVPGSSSTSTSSWYYTHA
What are the official names of this protein?
Uncharacterized protein A37.5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxviruses A37.5 protein family.
Protein: TSN31_MOUSE
Sequence: MVCGGFACSRNALCALNVVYMLVGFLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAANHHQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWSVLSNSTRHELERSFDCCGLFNLTTLRLQDDTSCSAVCKTKSSTCQMCGERFLKHSDKALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL
What are the official names of this protein?
Tetraspanin-31, Tspan-31, Sarcoma-amplified sequence homolog.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: H3_NARPS
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPTTGGVKKPHRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSHAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus, nucleolus. Note=Localized at rDNA loci in the nucleolus.
Protein: S2538_DEBHA
Sequence: MVSDVSEPSDTTPEVVVQQQPQPKTLTHLISGASAGLISAISLQPFDLLKTRLQQQQRSNIKYRTTISKELKKLTHIRDLWRGALPSTLRTSVGAGLYFTILSSARNGISDYKRSSDSVSDTSILPKLSPFENLATGFIVRAVVGIITMPITIVKTRYESNIYNYNSMYEGFENIYLDGNQKGQGSLKNFFKGSFATLARDCPYAGMYVLFYELFKNDILTKVVPPIDETENGPITRSTIINTSAAILAASVSTTITAPFDAIKTRLQLSSIVASKKMTLWSATKDLMREDGGVKNLFRGLSLRFGRKGLSSGISWCIYEELIKSNFAQVIITKSDKKLV
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COAE_SYNY3
Sequence: MDTKPPRQRLIGLTGGIATGKSTVTDYLQQKYSVPILDADLYARQAVEPGSEILVAIARRYGPEILDQQGQLKRQALGEIVFNNAEEKQWLESQIHPFVGRCFRSALAQLKQEQTVLLSIPLLFEAQLTDWVTEIWVVTCGPQQQVERLIKRNGLTEAEALARITSQMPLAEKVALADVVLDNSGQIADLEPQIIKAWHHR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALS_PAPHA
Sequence: MALRKGGLALALLLLSWVALGPRSLEGAEPGTPGEAEGPACPATCACSYDDEVNELSVFCSSRNLTRLPDGIPGGTQALWLDSNNLSSIPPAAFRNLSSLAFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLAVGTFAYTPALALLGLSNNRLSRLEDGLFEGLGNLWDLNLGWNSLAVLPDAAFRGLGGLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFAQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFEDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKVGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFAGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHQLFQGLGKLEYLLLSHNRLAELPADALGPLQRAFWLDVSHNRLEALPGSLLASLGRLRYLNLRNNSLRTFTPQPPGLERLWLEGNPWDCSCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPVYTYNNITCASPPEVAGLDLRDLGEAHFAPC
What is the function of this protein?
Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
What are the official names of this protein?
Insulin-like growth factor-binding protein complex acid labile subunit, ALS.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TAM_MYCUA
Sequence: MWDPAVYLAFADHRGRPFYDLVSRIGAKRARRVVDLGCGPGNLTRYLARRWPEAIIEAWDSSPQMVAAARERGIDATTGDLRTWKPKPDTDVVISSAALHWVPEHADLMVQWATVLPHGSWIAVQVPGNFETPSHAVVRALARREPYAKLVRDIPFRVGAVVGSPASYAGLLMDAGCKVDAWDPTYLHQLTGKNPVLEWITGTALVPVRERFDDVSWEQFRQELIPLLDDAYPPRSDGTTMFPFRRLFIVAEVGGARRSADVS
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEN1_YEAST
Sequence: MNSNNPDNNNSNNINNNNKDKDIAPNSDVQLATVYTKAKSYIPQIEQVYQGTNPNIQEAKLLGELLQVLAEVPKGTHLFCDPILEPISIFSLTIFSFNEEATATWLKNHFNPILSVCDKCILNFARGKCKMLQHFAIQRHVPHEHVAKFNDIVCQWRVEAVFPILRNISVNDNTGINITNEIETAMYECLCNPHMLRLNKQLKATFEAIFKFFYDTKHRLLDVTNPLSIKTFISGVIFCWCEGSKEENEWSRAFLKDLYSRNFHINLSNLTPDIIEEVYIHILFLQNPANWTEIVVSQFWSRLLPVFNLFDKDVFIEYFQVPKNVESLKKTFKFPLEPIFKMWYNHLSKSYHDKPLDFLLRGLTMFLNKFGSEFWSKIEPFTFHSILDIIFNRDSFPIKLIKIQDNPIVEHQTEVYFQLTGSVTDLLSWTLPFYHALSPSKRIQMVRKVSMAFLRIIANYPSLKSIPKACLMNSATALLRAVLTIKENERAMLYKNDEFETVLLTKTDSRALLNNPLIQDIIIRSASNPNDFYPGLGAASASVATSTMMVLAECIDFDILLLCHRTFKLYSGKPISEIPISTNVLENVTNKIDLRSFHDGPLLAKQLLVSLKNINGLLIVPSNTAVAEAHNALNQKFLLLSTRLMEKFADILPGQLSKILADEDASQGFWSCIFSSDKHLYQAATNILYNTFDVEGRLEGILAILNSNLTVNLKNINVMLQRLINCEFYEPCPRAVRVLMDVVSAFVDPISGVFANFQTLKSQNTEKEFLKFWESCWLFLDTIYKFTLKWASKYDYSELENFTKDTLDLSRSLVDSFREFSDILHDQTKNLLLNVLETFKNMLYWLRLSDEVLLESCVRLIISTSDLAHEKHVKVDDSLVEMMAKYASKAKRFSNKLTEQQASEILQKAKIFNKALTEEVATEAENYRKEKELSRLGKVIDLTDSVPASPSLSPSLSSTIASSSAESRADYLQRKALSSSITGRPRVAQPKITSFGTFQSSANAKLHRTKPVKPLSKMELARMQLLNNRVVHPPSAPAFHTKSRGLSNKNDDSSSEESDNDIESARELFAIAKAKGKGIQTVDINGKVVKRQTAAELAKQELEHMRKRLNVDMNPLYEIILQWDYTRNSEYPDDEPIGNYSDVKDFFNSPADYQKVMKPLLLLESWQGLCSSRDREDYKPFSIIVGNRTAVSDFYDVYASVAKQVIQDCGISESDLIVMAYLPDFRPDKRLSSDDFKKAQHTCLAKVRTLKNTKGGNVDVTLRIHRNHSFSKFLTLRSEIYCVKVMQMTTIEREYSTLEGLEYYDLVGQILQAKPSPPVNVDAAEIETVKKSYKLNTSQAEAIVNSVSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVPLEKNSSNTEQLLKKQKILICAPSNAAVDEICLRLKSGVYDKQGHQFKPQLVRVGRSDVVNVAIKDLTLEELVDKRIGERNYEIRTDPELERKFNNAVTKRRELRGKLDSESGNPESPMSTEDISKLQLKIRELSKIINELGRDRDEMREKNSVNYRNRDLDRRNAQAHILAVSDIICSTLSGSAHDVLATMGIKFDTVIIDEACQCTELSSIIPLRYGGKRCIMVGDPNQLPPTVLSGAASNFKYNQSLFVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAPYKFFDIISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRDLIEDAKDRSCLAYACSGFLDPRNNRAQSILRKFNVPVPSEQEDDYKLPMEYITQGPDEVKSNKDTKKRRVVDEGEEADKAVKKKKKEKKKEKKKSKADDKKKNNKKAESPSTSSGTKKKSSIFGGMSVPSAVVPKTFPDVDSNKKAAAVVGKKKNNKHVCFSDDVSFIPRNDEPEIKVTRSLSSVLKEKQLGLKETRTISPPEISNNEDDDDEDDYTPSISDSSLMKSEANGRNNRVASHNQNFSASIYDDPQVSQAKQTQVPAAITKHRSSNSVLSGGSSRILTASDYGEPNQNGQNGANRTLSQHVGNANQYSTAPVGTGELHETLPAHPQDSYPAEAEDPYDLNPHPQPQSSAFKGPGSGPTGTRNSSRRNASSSPFIPKKRKPRS
What is the function of this protein?
ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) and nucleolar (snoRNA) RNAs.  Directs RNA polymerase II transcription termination on snoRNAs as well as on several short protein-coding genes.  May also play a role in transcription-coupled nucleotide excision repair.
What are the official names of this protein?
Helicase SEN1, tRNA-splicing endonuclease positive effector.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRFA_SHESR
Sequence: MMKKMTGKSFALSALVAASFMAAGAMASDKTEPRNEVYKDKFANQYNSWHDTAKSEEITDALAGDPSLVILWAGYGFAKDYNAPRGHMYAVTDVRNTLRTGAPTNAEDGPMPMACWSCKSPDVPRLIEEQGEDGYFKGKWAKGGPEVVNTIGCSDCHEKGTPKLRISRPFAERGMEALGTPFDKASKKDKQSMVCGQCHVEYYFEKKDDRKGFVKFPWDSGTTVEQMEAYYDAIEFSDWTHSLSKTPMLKAQHPGYETWKMGVHGKNDVSCVDCHMPKVTNDKGRKYTDHKVGNPFDRFDETCATCHSQSKEFLEGITKERYAKVKELKARAEGQLVKAHFEAAKAWEVGATEAEMKPILTDIRHAQWRWDFAIASHGVAAHAPEEALRILGTAVDKAADARVKLAQLLAKKGVTDAVAIPDISTKAKAQAALGMDMDKMNAEKEAFKKDMLPKWDAEAKKREATYK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYH_STRTD
Sequence: MKLQKPKGTQDILPGDSAKWQYVENVARETFKKYNYGEIRTPMFEHYEVISRSVGDTTDIVTKEMYDFHDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQKPVKVYYIGSMFRYERPQAGRLREFHQLGVECFGSKNPATDVETIAMAYQLFNTLGIKDVTLHLNSLGNTDSRLAYRQALIDYLTPMRESLSKDSQRRLEENPLRVLDSKEKEDKVAVENAPSILDYLDEESQTHFDEVRAMLDSLNIPYVIDTNMVRGLDYYNHTIFEFITTIDKSELTICAGGRYDSLVEYFGGPETAGFGFGLGLERLLLVLDKQGIKLPVEESLDVYIAVLGSGANGKALELVQSIRYQGFKAERDYLGRKIKAQFKSADTFKAKTVITLGESEVESGVVKVKNNATREEVTVSFEELTTNFATVLKQLEK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_AGRRK
Sequence: MAEVKYEPRLKKEYVARIRAALQEKFSYANEMQIPKLDKIVINMGVGEATADSKKPTVAAADLAAIAGQKPVITHARNSIAGFKVRENMPIGAKVTLRGARMYEFLDRLVNIALPRVRDFRGLNPKSFDGRGNFAMGIKEHIVFPEINYDKVDQMWGMDIIVCTTATTDDEARALLKEFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL2_METEP
Sequence: MALKTFKPVTPSLRQLVLVDRRELYKGKPVKALTEGKSSSGGRNNLGRITVRFRGGGHKRVLRNVDFKRRENLNVPATVERIEYDPNRTAFIALITFPDGKQSYILAPQRLSPGDKVIAGESVDVKPGNAAPIGSMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGRDQGYVTLRLNSGEQRLVHGQCFATVGAVSNPDHMNISLGKAGRNRWLGKRPHVRGVAMNPVDHPHGGGEGRTSGGRNPVTPWGVPTKGKKTRSNKRTDTFILSSRHNRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CAPSD_HBVC4
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSESPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TOM20_CAEBR
Sequence: MTDTLFGFNKSNVVLAAGVAGAAFLGYCIYFDHKRINAPDYKDKIRQKRRAQAGSGGMAARRPPAGGNEMAPDVTDPSQMQRFFLQEVQLGEELMAAGNVEEGAVHIANAVMLCGESQQLLSIFQQTLSEEQFRAVVQQLPSTRERLADMFGARADEAENEPPLVQYLGDGPPPAQIQELIDDTDDLE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Translocase of outer mitochondrial membrane protein 20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RHAB_LISMH
Sequence: MKHYVAVDIGASSGRLILGKLVNEKLQLEEIHRFKNGFTYRDGHERWEIDQLMQEIFIGLEKVKQLGILECVLGIDTWGVDYVLIGASGEKLADPISYRDKRTLNAVQNLTSEYPREYIYKKTGIQFMELNTLYQLYVEERDLLERAEKILLIPDYIGYVLTGVKVAETTNSSTTQMLNLREQLFDKDLLSHLNIDVEKFAPLTDAGTYLGKVKEEWLEEYDIPNCDVVTVATHDTASAVVGTPAEGENWAFLSSGTWSLIGMELSAPINNEAAFKENYTNEWGAYGTYRFLKNIMGLWIVQEIARMDDYKHSFAEMAEEASNYPYFKQIINVNDARFNNPENMVDEIKLYCQETGQTIPETIGELTNCVYGSLALYYALELEKMTEITGKKIEKLYIVGGGSNVAMLNQLTAKLAGIEVFAGPSEATAIGNLVVQMINQGEIESMRAGRKIIRNSFEIGEFSCGDVRFEEIKERFTKVLEFN
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: RL31B_ECOLU
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: GUAC_EXIS2
Sequence: MMDVVFDYEDIQLIPAKSIVGSRSECDTTVEFGGRRFKLPVVPANMQTIIDEKIATFLAENGYFYIMHRFEPETRLNFVREMQQRGLIASISVGVKTEEYTFIETLAQEGLTPEYITIDIAHGHSEAVIRMIQHIKQILPESFVIAGNVGTPEAVRELEHAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDIAKSVRFGATMVMIGSLFAGHEESPGEMQEVDGLQVKEYFGSASEFQKGEKKNVEGKKMFIEFKGSLSDTLTEMEQDLQSAISYAGGNKLQAIRTVDYVVVKNSIFNGDKVY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.