PharMolix/UniProtQA huggingface dataset:
Protein: Y1209_CLONN
Sequence: MSSKIILLILMFLSFISKNKSLGIATIVMLFISFFNTEKCITFMENHFMNLGMTFLMIWMLIPIIKNPEFTENIKNAFNLKGIVCFLCGAIVAVLASKGVGFLKGSTDTLTGIILGSIVGVSLLGGVPVGPLIASGIAYEVVFIINLIFKNNC
What are the official names of this protein?
UPF0756 membrane protein NT01CX_1209.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AGLG_HALVD
Sequence: MKVSVVVCTYSMERYESFSETVESVLAQTYEPLELVIVVDGNEEEFDRVQDDFGDIDDVVLHCNDENRGISYSRTKGAELGTGDVVAMIDDDATAEPDWIETLVDTYENNPDAVAVGGTVVPDWVARKPEFFPEEFYWLVGCDERGFGEHMEEVRNTYGSNISFKRDVFLEVGGYDTNTGRKGDKHVQAHEAPVCIRIYEQTGERVIYNKQARVNHKLFEYRTEFDWLVFRSFWQGYSKRVMDLLYPQASDDKNAYLKDLMLVYVVDRLKNLVEDPSLAQVQQLIAIFVFTAAVGFGYVYGLLTPNLVEKTNN
What is the function of this protein?
Involved in the protein N-glycosylation pathway responsible for the assembly and attachment of an N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins (PubMed:18631242, PubMed:21091511, PubMed:22730124).  Catalyzes the transfer of a glucuronate residue (GlcA) to a glucose residue already bound to a dolichol phosphate (DolP), a compound that serves as a glycan lipid carrier in Archaea.  In vitro, is able to add GlcA to DolP-Glc in which the omega-position isoprene is not saturated.  However, the likely physiological lipid substrate is alpha,omega-saturated (PubMed:28809486).
What are the official names of this protein?
Glucosyl-dolichyl phosphate glucuronosyltransferase, Archaeal glycosylation protein G, Glycosyltransferase AglG.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: POL3_DROME
Sequence: TGRKFSATSLGKPQYITIKYKENNLKCLIDTGSTVNMTSKNIFDLPIQNTSTFIHTSNGPLIVNKSIIIPSKILFPTTNEFLLHPFSENYDLLLGRKLLAEAKATISYRDQEVTLYNNKYKLIEGIATHEQSHFQNVNMIPDTMLRQPNKISPILESDLYRLEHLNNEEKQRLCALLQKYHDIQYHEGDKLTFTNQTKHTINTKHNLPLYSKYSYPQAYEQEVESQIQDMLNQGIIRTSNSPYNSPIWVVPKKQDASGKQKFRIVIDYRKLNEITVGDRHPIPNMDEILGKLGRCNYFTTIDLAKGFHQIEMDPESVSKTAFSTKHGHYEYLRMPFGLKNAPATFQRCMNDILRPLLNKHCLVYLDDIIVFSTSLDEHLQSLGLVFEKLAKANLKLQLDKCEFLKQETTFLGHVLTPDGIKPNPEKIEAIQKYPIPTKPKEIKAFLGLTGYYRKFIPNFADIAKPMTKCLKKNMKIDTTNPEYDSAFKKLKYLISEDPILKVPDFTKKFTLTTDASDVALGAVLSQDGHPLSYISRTLNEHEINYSTIEKELLAIVWATKTFRHYLLGRHFEISSDHQPLSWLYRMKDPNSKLTRWRVKLSEFDFDIKYIKGKENCVADALSRIKLEETYLSEQTQHSAEEDNSDLIFITERPLNTFNRQVIFSKGPPDIKVTKYFKKHITQIFYDIMTREKAEQYLIDHFCGKKSALYIESDADFEVIQAAHKLAINTKYTKILRSTILLKNITTYAEFKELILTAHEKLLHPGIQKTTKLFGETYYFPNSQLLIQNIINECSICNLAKTEHRNTDMPTKTTPKPEHCREKFMIDIYSSEGKHYVSCIDIYSKFATLEEIKTKDWIECKNALMRIFNQLGKPKLLKADRDGAFSSLALKRWLESEEVELQLNTTKTGVADIERLHKTINEKIRIIKTSDDEETKLSKMETVLNIYNHKTKHDTTGQTPAHIFLYAGQPILDTQQNKENKINKINNDRVEYEVDTRYRKGPLQKGKLENPFKPTKNVEQTDSDHYKITNRNRITHYYKTQFKKRKKNNQLSISQAPGT
What are the official names of this protein?
Retrovirus-related Pol polyprotein from transposon 17.6.
Protein: UXP_ADE05
Sequence: MKIVGADGQEQEETDIPFRLWRKFAARRKLQYQSWEEGKEVLLNKLDRNLLTDFKAFAARFSSRPRPSKIFGTSLSEAISGEGNGQSGRGAARNHPRARTRCGATSPNHGGRVVPVPVAAASPGAPKKADEAAYRVRGRGRLITRRAGAAHTQPAAIDLGGGFGHCAQEEKEAPFSQARAPAITRGNRGQRGRKRRCGATNGGFQQPTGANQAWQRR
What is the function of this protein?
Might play a role in viral replication since it is associated with viral replication centers.  Seems to have an effect on DBP localization.
What are the official names of this protein?
U exon protein, UXP.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae U exon protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=At 18 to 24 hours postinfection, UXP is strongly associated with nucleoli and is found throughout the nucleus. Later, UXP is associated with the periphery of replication centers.
Protein: FTHS1_STRPM
Sequence: MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLLLVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFTEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 1, Formyltetrahydrofolate synthetase 1, FHS 1, FTHFS 1.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DAPLE_HUMAN
Sequence: MDVTVSELLELFLQSPLVTWVKTFGPFGSGSQDNLTMYMDLVDGIFLNQIMLQIDPRPTNQRINKHVNNDVNLRIQNLTILVRNIKTYYQEVLQQLIVMNLPNVLMIGRDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLELPDVAPEELEALSRSMVLHLRRLIDQRDECTELIVDLTQERDYLQAQHPPSPIKSSSADSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVDQLVLELQKVKQENIQLAADARSARAYRDELDSLREKANRVERLELELTRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARARGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQGEGQHLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMENKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPPPKKKNHWIGAKALVKLIKPKKEGSRERLKSTVDSPPWQLESSDPASPAASQPLRSQAENPDTPALGSNCAEERDAHNGSVGKGPGDLKPKRGSPHRGSLDRTDASTDLAMRSWPSELGSRTCSTSATTTAPSNSTPIARHPGRTKGYNSDDNLCEPSLEFEVPNHRQYVSRPSSLESSRNTSSNSSPLNLKGSSEQLHGRSESFSSEDLIPSRDLATLPREASTPGRNALGRHEYPLPRNGPLPQEGAQKRGTAPPYVGVRPCSASPSSEMVTLEEFLEESNRSSPTHDTPSCRDDLLSDYFRKASDPPAIGGQPGPPAKKEGAKMPTNFVAPTVKMAAPTSEGRPLKPGQYVKPNFRLTEAEAPPSVAPRQAQPPQSLSLGRPRQAPVPPASHAPASRSASLSRAFSLASADLLRASGPEACKQESPQKLGAPEALGGRETGSHTLQSPAPPSSHSLARERTPLVGKAGSSCQGPGPRSRPLDTRRFSLAPPKEERLAPLHQSATAPAIATAGAGAAAAGSGSNSQLLHFSPAAAPAARTKPKAPPRSGEVATITPVRAGLSLSEGDGVPGQGCSEGLPAKSPGRSPDLAPHLGRALEDCSRGSVSKSSPASPEPGGDPQTVWYEYGCV
What is the function of this protein?
Required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling (PubMed:26126266).  Binds to ligand-activated Wnt receptor FZD7, displacing DVL1 from the FZD7 receptor and leading to inhibition of canonical Wnt signaling (PubMed:26126266).  Acts as a non-receptor guanine nucleotide exchange factor by also binding to guanine nucleotide-binding protein G(i) alpha (Gi-alpha) subunits, leading to their activation (PubMed:26126266).  Binding to Gi-alpha subunits displaces the beta and gamma subunits from the heterotrimeric G-protein complex, triggering non-canonical Wnt responses such as activation of RAC1 and PI3K-AKT signaling (PubMed:26126266).  Promotes apical constriction of cells via ARHGEF18 (PubMed:30948426).
What are the official names of this protein?
Protein Daple, Coiled-coil domain-containing protein 88C, Dvl-associating protein with a high frequency of leucine residues, hDaple, Hook-related protein 2, HkRP2.
What is the protein family that this protein belongs to?
Belongs to the CCDC88 family.
Protein: NELFD_PONAB
Sequence: MAGAAPGAIMDEDYYGSAAEWGDEADGGQQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNKRVSINKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity).  The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity).
What are the official names of this protein?
Negative elongation factor D, NELF-D, TH1-like protein.
What is the protein family that this protein belongs to?
Belongs to the NELF-D family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_STRSV
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEHLLRTRNTLEKILAENSGKSVEQIHKDAERDYWMSAQETLEYGFIDEIMENSNLS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_XYLF2
Sequence: MAAKEIIFSEKARSRMVHGVNLLANAVKATLGPKGRHVVLDKSFGSPIITKDGVSVAKEIELADKFENMGAQMLKEVASKTNDHAGDGTTTATVLAQALIREGCKAVAAGMNPMDLKRGIDKAVIAAVTELKKISKPTSDDKAIAQVATISANSDESIGNIIAEAMKKVGKEGVITIEEGTTLENELDVVEGMQFDRGYSSPYFINNQQSQIVELDNPYILLHDKKISSVRDLLTVLDAVAKESKPLLIVAEEVEGEALATLVVNNIRGIIKVCAVKAPGFGDRRKAMLEDMAVLTGGTVISEEVGLSLEKATTSHLGKAKKVRVSKENTTIIDGMGDNDAINGRVKQIKTQIEETTSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALLATRAAVEEGVIPGGGVALIRAITAISNLKGANEDQTHGIQIALRAMEAPLREIVANAGEEPSVILNKVKEGKDNFGYNAATGEFGDMVNLGILDPTKVTRSALQNAASIAGLMITTEAMVAEAPKKDEPTPPAAGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_MYCMM
Sequence: MTNDPAEISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLADIDLSAEFFGAPLRAPVLIGAMTGGAELSATINRNLATAAQRLGIGMMLGSQRIMLDDARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAALRRVGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLKEVGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRYPELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKAIALGADVVAIARPLLAPAIESATAVQGWLQLFLDELRVCLHCCGARDLTSLRDIGVTAIR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_EHRRG
Sequence: MNMLLEINDLNSYDIEFIFDTAIQHFNNSNVSNNSLYGKTIVNLFFESSTRTLSSFEISAKSLGARTVTINVSTSSMNKGESIIDTVLNINAMNPDLIIIRSQYSQFIKEISKYLPNCHIINAGDGHHEHPTQALIDYCTIRYIKGKIHNLNISICGDILHSRVARSNIRLLSRYGANISIVAPPTLICNLKGVSHIHHNFVEGISDSDVIMLLRLQKERMTNFTISSEEEYAYLYMLNSENLSYARSDVIVMHPGPTNKGVEISHYVAEKKSIILLQVKMGVAVRKAILEYLLCHN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MATK_TRISR
Sequence: MKEYQVYLERARSRQQDFLYPLIFREYIYGLAYSHNWSRSIFVENGGYDNKYSLLNVKRLITRMYQQNHLIISANDSPKNPFWGYNKNFDSQIISEGFAIVVEIPFFLQLNSSLKEAEIIKSYKNVRSIHSIFPFLEDKFTYLHYVSDIRIPYPIHLEILVQILRYWVKDAPFFHLLRLFLYHFSNWNRFITTKKSISTFSKRNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFLERIFFYAKREHLVEVFAKDFSYPLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKHYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVQLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFYRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LFA3_HUMAN
Sequence: MVAGSDAGRALGVLSVVCLLHCFGFISCFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDEDEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSIILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTNSN
What is the function of this protein?
Ligand of the T-lymphocyte CD2 glycoprotein.  This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes.  In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
What are the official names of this protein?
Lymphocyte function-associated antigen 3, Ag3, Surface glycoprotein LFA-3.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
Protein: WNT7A_PLEJO
Sequence: SGSCTTKTCWTTLPKFRELGYVLKDKYNEAVQVEPVRASRNKRPTFLKIKKPLSYLKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRMCNKTAQHSSGCDLMCCGRGYNTHQYSRVWKCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity).  Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development.  Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity).
What are the official names of this protein?
Protein Wnt-7a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: YIDD_MYCPA
Sequence: MTGPARSGAAIRGAGRTVARGLIFLIQLYRHMVSPLRPATCRFVPTCSQYAVDALDEYGLIRGSWLAAARLAKCGPWHQGGWDPIPERPGCRVNCQDASDAWAVRATRGESGSLV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YDFA_ECO57
Sequence: MDTIDLGNNESLVYGVFPNQDGTFTAMTYTKSKTFKTENGARRWLERNSGE
What are the official names of this protein?
Uncharacterized protein YdfA.
What is the protein family that this protein belongs to?
To E.coli YdaF.
Protein: FABZ_VIBVU
Sequence: MTTEKKTMNISEIQELLPHRYPFLLIDRVVDFQEEKYLHAIKNVSVNEPQFTGHFPQLPVFPGVLILEAMAQATGLLAFKSFGAPSENELYYFASVDGAKFRKPVVPGDQLIIEVEFIKERRGIAAFTGVAKVDGDVVCSAELKCARREF
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C8_VACCC
Sequence: MSSIRFIACLYLISIFGNCHEDPYYQPFDKLNITLDIYTYEDLVPYTVDNDLPNPNDDTTSFVKIYFKNFWITVMTKWCAPFIDTVSVYTSHDNLNIQFYSRDEYDTQSEDKICTIDVKARCKHLTKREVTVQKEAYRYSLSSDLSCFDSIDLDIDLIETNSTDTTVLKSYELMLPKRAKSIHN
What are the official names of this protein?
Protein C8.
What is the protein family that this protein belongs to?
Belongs to the poxviridae C8 protein family.
Protein: CSPLI_MAIZE
Sequence: MKDVVGSPGTWSGMALRLSQCVSAGASMGAMATAYGFSNYTAFCYLIASMGLQLLWSFGLACLDVYSLKTKRDLHNPVLVSLFVVGDWVTAILSFAAASASAGVTILFERDVHFCRMYPQLSCGRYALSVVLAFITWSFIATSAVSMFWLLPSL
What are the official names of this protein?
CASP-like protein 5B3, ZmCASPL5B3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLRC_IDEDE
Sequence: MKTNILVKRMAVIGLAVAAACTGAAAAAQGAVPQAQRIIRVLSVAGGDAASPQAAVWKKAPTTQVTLLTAFPGHISIVGTAATQKLAAQAVRASGRLFVRLAWSDRTANTVMKDTDQFLDGAAVEFPVNGKVATLPFMGDPVNVVNVWHWRADGRTLNLLAKGFGTSTPVPTEDLRSASVRTGDGWEVVLSRPLRVKAEEGANLQGRRTMPIGFAAWDGENQERDGLKAVTMEWWQLRF
What is the function of this protein?
May transfer electrons to the iron-sulfur centers of ClrB.
What are the official names of this protein?
Chlorate reductase subunit gamma, Chlorate reductase heme subunit.
What are the subcellular locations of this protein?
Periplasm.
Protein: PTH_BURPS
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLVDQLAREAGATLRDERRFHGFYAKARLFGEEVHLLEPQTYMNRSGQAVVALAHFFKILPTEILVAHDELDLPPGAAKLKLGGGSGGHNGLKDISAHLSSQQYWRLRIGIGHPRDLIPESARAGAKPDVANFVLKPPRKDEQDLINAAIERALAVMPTAIKGETERAMMQLHRNGA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PSEAB
Sequence: MRRPLVAGNWKMHGTHSSVAELIKGLRQLALPSGVDVAVMPPCLFISQVIQGLAGKAIDVGAQNSAVEPMQGALTGETAPSQLADVGCSMVLVGHSERRLILGESDEVVSRKFAAAQSCGLVPVLCVGETRAEREAGKTLEVVARQLGSVIDELGVGAFARAVVAYEPVWAIGTGLTASPAQAQEVHAAIRAQLAAENAEVAKGVRLLYGGSVKAASAAELFGMPDIDGGLVGGASLNADEFGAICRAAGS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF28_NEOYE
Sequence: MTKNCLNQENCIPIFSENSSGDFFSCNPWLLFFNRNKINYQIFSLKKNDTLLFNSSSRLYIILIGSLIITKVLRNTHKVTLNLLTTGDTFGQIELVDDNFYYEAEAIDKTEVACINYTTIIKACSNCAPFNLFFVNHLVFCSAKAYHFIEIISHKSITSRLASLLLLLAEQNGTQVNNGIMLNFTITHKILAQIIGSNRVSVTRILANLLKTKLISIQKKRIIVHSPVLLSQRILNQ
What are the official names of this protein?
Putative HTH-type transcriptional regulator ycf28.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PIGU_HIRNI
Sequence: TDCGGKTCSEAQVCKDGKCVCVIGQCRKYCPNGFKKDENGCTFPCTCA
What is the function of this protein?
Inhibits plasma and tissue kallikrein, and trypsin.  May be involved in leech hematophagia.
What are the official names of this protein?
Piguamerin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I15 (antistasin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_ACIBT
Sequence: MQDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYSVEDLTHIVSRSANLMDVPITVEGAEEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVNHEMAQRALDMLNVDKAGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNQSYLQFGMTPPEPKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: VP7_ROTP3
Sequence: MYGIEYTTVLTFLISVILLNYILKSLTRIMDFIIYRFLFVIVILLPLLSAQNYGINLPITGSMDTPYINSTQGEVFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSVYFKDYTDIASFSVDPQLYCDYNLVMMKYDATLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDTNTFEEVATAEKLAITDVVDGVNHKLSVTTNTCTIRNCKKLGPRENVAVIQVGGSDILDITADPTTAPQTERMMRVNWKKWWQVFYTIVDYVNQIVQAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.