PharMolix/UniProtQA huggingface dataset:
Protein: YEHG_SCHPO
Sequence: MLGKEWENTSFAEIGLLHQAPNDNDLEKFQHALTLMSEADNSSDLLIPLISDFLIWFYYQKTPLKWIPFLGHFFNTWQSCSFPPRRYLLAKILSGRISELLKVSPFELAASVTSQDVVEADSLVEENELQAWLEKQELVPSSSNFLNSFWISGGERELTEEEQNSLLQSNTTYTNSDLPASKQLESFISMNLSYSKVFFLHLLQHSDSSFNDKFLLLLANIPVTVSNVEVLLYLLQQEESLAQFDLNGKSFLYHMLVSLHNQVTNTSHLEKQRISTVATLFISKLFEIPSLSEYLSSTLFLDLQAFCIVALPQSAKLFQKVKALKNNP
What are the official names of this protein?
Uncharacterized protein C23H4.16c.
Protein: GAMR_BACSU
Sequence: MTALYSVIKFKIIELIKSGKYQANDQLPTESEFCEQYDVSRTTVRLALQQLELEGYIKRIQGKGTFVSAAKIQTPIPHKITSFAEQMRGLRSESKVLELVVIPADHSIAELLKMKENEPVNKLVRVRYAEGEPLQYHTSYIPWKAAPGLAQEECTGSLFELLRTKYNIEISRGTESIEPILTDETISGHLLTNVGAPAFLSESLTYDKNEEVVEYAQIITRGDRTKFTVEQSYHS
What is the function of this protein?
Transcriptional repressor of genes involved in glucosamine transport and utilization.  Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region.
What are the official names of this protein?
HTH-type transcriptional repressor GamR.
Protein: CH60_ECO5E
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I22_CONVX
Sequence: MMFRLTSVSCFLLVIACLNLFQVVLTSRCFPPGIYCTPYLPCCWGICCDTCRNVCHLRFGKRATFQE
What is the function of this protein?
Inhibits the vertebrate voltage-gated potassium channels Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-conotoxin-like 2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GIPR_HUMAN
Sequence: MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
What is the function of this protein?
This is a receptor for GIP.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCNA_METBU
Sequence: MFKATIDAYLLKDSIETLSVLVDEARFRISPEGVVVRAVDPANVAMVSFDLTPEAFDDFEANDCELGLDLSRINDILGVADRDDKVQMELDEESKKLKIQIGGFSYTISLLDPSTIRAEPRIPQLELPAEIVLNGKDLQKAVKAAEKISDHMLLGVEGESFFMEAEGDTDRVKLTMTRDQLIDIKPSQVRSLFSLDYLSDIIKPASKSNEISLHLGNDFPIKINFSIANGKGTIGYLLAPRIESD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RSMH_GLAP5
Sequence: MSDSPKHITVLLHEAVDGLAIKPNGIYVDGTFGRGGHSRLILSKLGEQGRLIAIDRDPRAIAEANTITDPRFQIVHSAFSSIPDICDELNLVGKIDGILLDLGVSSPQLDEAERGFSFMRDGPLDMRMDTTKGLSAMEWLAQVSVDDLAWVLKEFGEERFAKRIAQAVVSYNKSATEKISRTLQLAQIIADVVPFKDKHKHPATRSFQAIRIYINSELDELEKALNSALTVLAPEGRLSIISFHSLEDRMVKQFMRKQSKGETVPKGLPILESELNKNIPLKTVGKAIMPSEAEIEANPRSRSAVLRVAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_YERE8
Sequence: MAKVCIAAYVYGVVQGVGFRYSTQRQALALGVTGYARNCDDGSVEVVAYGEQQAVEQLMEWIKQGGPRGARVDRLLTEPYPATPFETFKIRY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: HDA_ECO45
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: LEU3_ZYGRC
Sequence: MSKNIVVLPGDHAGQEIAQEAIKVLEAISEVSPEAKFNFQHHLIGGAAIDATGSPLPDDALAAAKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYANLRPCNFASESLLDLSPLKPQHAKGTDFVVVRELVGGIYFGERKEDEGDGVAWDSEKYTKPEVQRLTRMAAFLALQHNPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPQLKLNHQLIDSAAMILVKSPTQLNGIVLTSNLFGDIISDEASVIPGSLGLLPSASLASLPDTNEAFGLYEPCHGSAPDLPKGKVNPIAMILSAAMMLKLSLNLSKEGEAVEKAVKQVLDSGVRTGDLGGSNSTSEVGDAIAKAVKEILA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_PSEPK
Sequence: MAVQRTFSIIKPDAVAKNVIGKITTRFEEAGLKIVASKMKQLSKAEAEGFYAEHSERGFFGDLVAFMTSGPVVVQVLEGENAIAKNRELMGATNPKEAAAGTIRADFAESIDANAVHGSDSEAAAAREIAYFFAATEVTTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PS19_PINST
Sequence: VVSLSIPR
What are the official names of this protein?
Putative LRR disease resistance protein/transmembrane receptor kinase PS19.
Protein: VPS18_DROME
Sequence: MDTSMPNQPKFLPRIEHNSSGATANSYVATASGNPFETDEEDEIFSRHKMVLRVPSNCTGDLMHLAVSRNWLVCLLGTPERTTLLRFFLPRAIPPGEAVLEKYLSGSGYKITRMFLDPTGHHIIIALVPKSATAGVSPDFLYIHCLESPQAQQLKVRRIEKFKDHEITAVAFNPYHGNESSTGPILLGTSRGLIFETELNPAADGHVQRKQLYDLGLGRPKYPITGLKLLRVPNSSRYIIVVTSPECIYTFQETLKAEERSLQAIFAGYVSGVQEPHCEERKTDLTFSQLRFFAPPNSKYPKQWAWLCGEGIRVGELSIEANSAATLIGNTLINLDFEKTMHLSYGERRLNTPKAFVLTEYHAVLLYADHVRAICLLNQEQVYQEAFDEARVGKPLSIERDELTGSIYVYTVKTVFNLRVTREERNVWRIYLDKGQYELATAHAAEDPEHLQLVLCQRADAAFADGSYQVAADYYAETDKSFEEVCLKFMVLPDKRPIINYVKKRLSRVTTKPMETDELDEDKMNIIKALVIWLIDLYLIQINMPDKDEEWRSSWQTEYDEFMMEAHVLSCTRQNRETVRQLIAEHADPRNMAQFAIAIGDYDEVVAQQLKAECYAEALQTLINQRNPELFYKYAPELITRLPKPTVDALMAQGSRLEVEKLVPTLIIMENREQREQTQRYLEFAIYKLNTTNDAIHNFLLHLYAEHEPKLLMKYLEIQGRDESLVHYDIYYAHKVCTDLDVKEARVFLECMLRKWISAVDLALTFDMKLAKETASRPSDSKIRRKLWLRIAYHDIKGTNDVKKALNLLKECDLLRIEDLLPFFADFEKIDNFKEAICDALRDYNQRIQELQREMAETTEQTDRVTAELQQLRQHSLTVESQDTCEICEMMLLVKPFFIFICGHKFHSDCLEKHVVPLLTKEQCRRLGTLKQQLEAEVQTQAQPQSGALSKQQAMELQRKRAALKTEIEDILAADCLFCGLLISTIDQPFVDDWEQVNVEWE
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes probably as part of the class C core vacuole/endosome tethering (CORVET) complex (PubMed:9065698, PubMed:10549280, PubMed:27253064, PubMed:25422373).  In larval neuromuscular junctions, essential for endosomal sorting which traffics old or dysfunctional synaptic vesicle proteins through a degradative endolysosomal route (PubMed:25422373).  Required for the biogenesis of eye pigment granules (PubMed:10549280).  Required to maintain normal levels of rush, which functions in endosome formation and trafficking (PubMed:22160599).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 18 homolog, Protein deep orange.
What is the protein family that this protein belongs to?
Belongs to the VPS18 family.
What are the subcellular locations of this protein?
Early endosome. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes.
Protein: RL7_KOCRD
Sequence: MAKLTTEELIEAFKELSLIELSDFVKAFEETFDVTAAAPVAVAGAAPAAGDAGAAEEEKTEFDVVLESAGDKKIQVIKEVRGLTSLGLKEAKDLVDSAPKAVLEGATKEAADKAKEALEGAGATVTVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS10_SULIL
Sequence: MPTKARIRLWSTNVENLNYVITQIRGIVEKTGIEMRGPIPLPTSKLEVPIMRLPHGEGRKKWEKWEMRVHKRLIDIAADERVMRQLMRVRVPEDVYIEIQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RIP_DROME
Sequence: MNSTQSPVYRTSVEQKRHAQEVAKRQRMGNQMPRLREMLREKYRKRIIETRNRCTDAQREIQLSELREILRLELSELEKDVELEELILEELLSDVNEWYALGEKNLETLYAEPDEQQKEVLCPVCQIKNLRHHKGAFICECGIRFEHSANMEQLQILLQQQIASHELQCTQALRFFIEPASGQLYDMCGSCDYFSSV
What are the official names of this protein?
RIP-like protein, RIP-alpha.
Protein: SYI_ESCF3
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_XANC5
Sequence: MPMSLRLHNNLTRRVEPFAPLDPSSPTLYVCGPTVYNYAHIGNARGPVVFDVLAALLRRRYGALRYARNITDVDDKINAAAQAQGVPISTITDRFAAIYRQDMAALGVVPPDIEPEATAHIPQIVAMIEQLIATGHAYAAEGHVLFSVSSFEDYGKLSRRDPDEMLAGARVDVAPYKRDPGDFVLWKPSSDDLPGWPSPWGRGRPGWHIECSAMAAAHLGPTIDIHAGGVDLQFPHHENEIAQSECAHGGATFARFWLHNGMLNFSGAKMSKSLGNIETVHELIARHPPEALRYALLSAHYRQPLDWSDGLIEQAKNTLDRLYGTLRDLAALEAESGSDLAVSMTIPAEVESALDDDLNTPLALSVMASIASDARALRSDLMQSGQASARMIELHAARAKLLGAGMALGLLQQDPAAWFSRGTDAGDDARITALVEERSAAKKAKDFARADAIRKQLAEEGIVLEDTPQGVRWKRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_AZOVD
Sequence: MSLGRVTVTAVRNLHPVTLNPSPRINILYGPNGSGKTSLLEAIHLLGLARSFRSQRLSPVIQHEQPACTVFGQVLWNDGRVRNLGVARNRLGELQIRIDGQNVRSAAQLAESLPLQLINPDSFRLLEGAPKVRRQFLDWGVFHVEQRFLPAWHRLQTALRQRNSWLRHGRIDPVSQAAWDRELCLASEEIDSYRRSYIQVLKPVFESVLHELVELDGLTLSYYRGWDRERSLGEVLAASLPRDQQLGHTQAGPQRADLRLRLAAHNAADLLSRGQQKLVVCALKIAQGHLVDRARRECIYLVDDLPSELDEQHRRALCRLLEELHCQVFITCVDLEALREGWRTDTPVALFHVEQGRITQTHDRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHY_PIG
Sequence: MMSAKDTVKVMVVMLAICFLARSDGKPIKKRSVSEIQLMHNLGKHLSSLERVEWLRKKLQDVHNFVALGASIVHRDGGSQRPRKKEDNVLVESHQKSLGEADKAAVDVLIKAKPQ
What is the function of this protein?
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.  Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).
What are the official names of this protein?
Parathyroid hormone, PTH, Parathyrin.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: YHE6_SCHPO
Sequence: MKTASIHFWSTLVLLFSCIGSVIAYSSTDLTTMYDWNQIIKPLEWGQMNFIHTTDTHGWLNGHLRDARYKADFGEFKSFVLRMKELADFKDVDLLLVDTGDLHDGNGLSDASDPEGIYTNNIFTYLPYDILTIGNHELYQASVSNNTHEYFVPHWNGTYLASNVQIFNSSNELEQFAAESAYFTTKHGVRVLAVGFLYDFTGNANNTVVTPVETAVNSRWYQQQINRTDVDLFLLLGHIPVRDWDEWKSLHASIRKVHPDTPIQIFGGHSHIRDFAVYDESSVSLEGGRYCETVGWLSIDGLAASNATRQYVGRPVTNETRQSYPNLPIPNTPLYYTRRYIDFNRQNFRFHTQQSEDSFDTPEGIELSKIIKQYRDDLNLSYVFGCVPKNYYMTEVSPQSDDSIFKLMTDRVLPEIITNRNRSTVPRIIISNGGGIRGSMYQGKFGPDEMFQLNPFLTNYYMYLADVPYKYAKKLYSTLNGGSNLRNINENLAALNPGYVTSDDFGEDGDDTVHTSVPSYATPNILQAQAGFNATSSPETIDVVFLNFLQSIVLKALNNMANDTLYTSSNVTQYWVRDDGYDSSPYSFAYFVQQEWSDNCD
What are the official names of this protein?
Uncharacterized protein PB2B2.06c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPX_MOUSE
Sequence: MSSCGACTCGAAAARLLTTSLTSAQRGISCGRIHVPVLGRLGTTLDAQALRRAPLRTFSETPAYFASKDGANKDGSGDGNKKSVTEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEAEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQMPQEKRGGEVLDSSQDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNVLFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSGESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPSKESSEEEYDSGVEEDGWPRQADAANS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease complex.  Hydrolyzes ATP.  Targets specific substrates for degradation by the Clp complex.  Can perform chaperone functions in the absence of CLPP.  Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure (PubMed:10347188).  ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase, thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis.  Important for efficient erythropoiesis through up-regulation of heme biosynthesis (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: WAP1_PSEPL
Sequence: MKTLTGLLLVGLLALWIGLPSTSSKILFGCGISPGNPFPCSLPGLTGNRCRRDYDCPQTLRCCNFRCSRSCRIPPVLPWSCPRNPFKCTIPGIDRCRYDYDCPGRQRCCYYSCSRICK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Waprin-Enh1.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCL24_CANLF
Sequence: MAGLATFVVSLLLVTLCAHCIDPAGSVSIPSSCCMFFISKKVPENRVVTYQLLNGSVCPKAGVVFTTKKNQKFCGDPQLHWVQKLMKNIEARRKKVSPGVRAMSTKALVQRYPANSTSI
What is the function of this protein?
Chemotactic for resting T-lymphocytes, and eosinophils.  Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes.  Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.  Binds to CCR3.
What are the official names of this protein?
C-C motif chemokine 24, Eosinophil chemotactic protein 2, Eotaxin-2, Small-inducible cytokine A24.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRET1_CULQU
Sequence: MWIEIPECYEVLRNVFSKFRRHSLTAAMVKLLMRADTHVSFTVPAEEPVAKCTFSQVLAALSVSLGSMVVGFSSAYTSPALVSMKDRNITSFEVTDQSGSWVGGIMPLAGLVGGILGGPLIEYLGRKNTILATATPFIISWLLIACATHVAMVLVGRALSGFSVGVASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGNYMDWSELAFLGATLPVPFLILMFLIPETPRWYVSRGRDDRARKALQWLRGKKADVDPELKGIIKSHQDAERHASQSAMLDLLKKTNLKPLLISLGLMFFQQLSGINAVIFYTVQIFQDAGSTIDENLCTIIVGVVNFIATFIATLLIDRLGRKMLLYISDIAMIITLMTLGGFFYVKNNGGDVSHIGWLPLASFVIFVLGFSLGFGPIPWLMMGEILPGKIRGSAASVATAFNWSCTFVVTKTFADIIASIGTHGAFWMFGSVCVVGLVFVIMYVPETQGKSLEDIERKMCGRVRRMSSVANIKPLSFNM
What is the function of this protein?
High-capacity facilitative transporter for trehalose.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph (By similarity).
What are the official names of this protein?
Facilitated trehalose transporter Tret1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXS_BORPA
Sequence: MTTELLDRILSPADLRQLDRRELKRLADELRGFVLESVSRTGGHLSSNLGTVELSLALHYVFDTPHDRIVWDVGHQSYPHKILTGRREGMAHLRQQGGISGFPKRSESEYDAFGTAHSSTSISAALGMAVASRNAGVQRQHIAVIGDGAMSAGMAFEAMNNAGVTPNINLLVVLNDNDMSISPPVGALNRYLARLMSGQFYAAAKNVGRAVLQHVPPVLELARRLEEHAKGMVTPATLFEEFGFNYVGPIDGHDLDALVPTLQNLRALPGLQFLHVVTRKGQGYKLAEADPVLYHGPGKFDPAVGIQQAKAPARKTFTQVFGQWLCDMAERDERLVGITPAMREGSGLVEFEQRFPQRYFDVGIAEQHAVTFAAGLACEGQKPVVAIYSTFLQRGYDQLVHDVALQNLDVTFALDRAGLVGADGATHAGNYDIAFLRCVPNMVVAAPSDESEARLLLSTCYEHPGPASVRYPRGAGCGAAVGEGLATVPLGKGLVRREGRRIAILGFGTLVQAALGAAGQIDATVADMRFVKPLDRELVLELAARHDALVTVEEAAIMGGAGSAVLETLAEAGVTLPVLQLGLPDAFIDHGDQAALLAGLGLDAAGIERAIRARFGALLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RK33_NEOYE
Sequence: MAKSKGARIVITLECSDKAGEFAQKRKPGVFRYTTTKNRRNTPSRIELNKFCPNCNQHCIFKEIK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BDEL_HIRME
Sequence: FDVNSHTTPCGPVTCSGAQMCEVDKCVCSDLHCKVKCEHGFKKDDNGCEYACICADAPQ
What is the function of this protein?
Strong inhibitor of mammalian trypsin, plasmin and acrosin.
What are the official names of this protein?
Bdellastasin, Bdellin A.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I15 (antistasin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EMC2_HUMAN
Sequence: MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELINEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINRAYQFAGRSKKETKYSLKAVEDMLETLQITQS
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176, PubMed:32439656).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231).  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835).  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
What are the official names of this protein?
ER membrane protein complex subunit 2, Tetratricopeptide repeat protein 35, TPR repeat protein 35.
What is the protein family that this protein belongs to?
Belongs to the EMC2 family.