PharMolix/UniProtQA huggingface dataset:
Protein: END4_STACT
Sequence: MLIGSHVSMNGKKMLQGSAEEAHRLNEKTFMIYTGAPQNTRRKAIEDLNIEAGHEAMKEYGLSNIVVHAPYIINIANTQKPHVFELGVDFLQKEIERTEAIGAKDIVLHPGSHVGAGSEAGIKKIIEGLNEVLTNDNDVRIALETMAGKGSEVGRTFEELAQIIEGVNHNERLSICFDTCHTHDAGYKVKDDFDSVLEEFDNVIGLDRIKVLHVNDSKNEIGAHKDRHENIGFGHIGFDALNYIVHHEVFENIPKILETPFVGEDKKNKRPPYKHEIEMLETETFNPNMKEIIMSE
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: ZG53_XENLA
Sequence: MGMWEEASDTGMKGKKKKKDKNEEEEEERGKKERMVNLTLEMIYLLTGEHYIPRKKSDDGGALHAPGSVIQKENNKNDEKILELMSNIIQLLTGEVAIRTHHVSIYFSLDEWDNIKGNKVLYEEGIKEEPQQLHPLDCEYEDKRDITADLGGTLCYNNETSKIGAEGTDFCAKENLTISPVEQPPPANRIKEERASCEEGNQSDCSINPLTEQIQGTDKPTPIMGYSLNNSSANYIKEEVVQCHEGNHSDMRIITAPESILETNTSAAMIRCNLNTSLSASCEGGNQSDCRINELTEQIQGTDTPTGNIVLYICSECQKHFSTKAGLARHQKTHSVFVGEEHAYGRIHTEEKPFPCSECGKRFARRQHLTDHQSSHTGEKPYACSQCEKYFPHRSNLNRHLKLHKGEKPFPCSQCGKRFPCVSDLNIHRRVHTGERPYSCSECGKCFKHHSNLTNHQRTHTREKPFSCTECGKGFKDRSSLTVHHRTHTGEKPFSCTECGKGFKDRSSLTVHHRTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF53.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_BACC2
Sequence: MLDIKFLRTNFEEVKAKLQHRGEDLTDFGRFEELDTRRRELLVQTEELKSKRNEVSQQISVLKREKKDAEALILEMREVGEKVKDFDNELRTVEEDLERLMLSIPNIPHESAPVGETEDDNVVARTWGEVKEFTFEPKPHWDLATDLGILDFERAGKVTGSRFVFYKGAGARLERALISFMLDLHTDEHGYEEVLPPYMVNRASMTGTGQLPKFEEDAFRIESEDYFLIPTAEVPVTNMHRDEILNKEQLPIRYAAFSSCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNDAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSYGTYREISSCSNFEAFQARRANIRFRREPNGKPEHVHTLNGSGLAIGRTVAAILENYQQEDGTIIIPEVLRPYMGGKTVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_MYCTU
Sequence: MAKVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDEDGEKRIPLDVAEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa antigen, 10 kDa chaperonin, BCG-A heat shock protein, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDL3_ORYSI
Sequence: MSDQPPPYTPLPLLSSFPPNPYPDQTPDPASTPTLVLPNPAFPNKRKRTGFRRKLPSGSPAAPVAVAASPSAQPPPRASAADDIIVINREPTAEAVTALTAGFPADSLTDEEIEAGVVSDVGGIEQVNYILIRNHLLTRWRETFNSWLAKESFATLIPPHCDHLLNAAYSFLVSHGHINFGVAPAIKERIPKEPTRHNTVIVVGAGLAGLAAARQLVAFGFKVVVLEGRKRCGGRVYTKKMEGGGRSAAGDLGGSVLTGTFGNPLGIVAKQLGLPMHKIRDKCPLYRPDGSPVDPEVDKKVEGTFNKLLDKSSLLRASMGDVAMDVSLGAALETLRQTDGDLSTDQEMNLFNWHLANLEYANAGLLSKLSLAFWDQDDPYDMGGDHCFLPGGNGRLVQALAENVPIVYERTVHTIRNGGDGVQVVVNGGQVYEGDMALCTVPLGVLKNGGVKFVPELPQRKLDSIKRLGFGLLNKVAMLFPHVFWSTDLDTFGHLTEDPSHRGEFFLFYSYATVAGGPLLMALVAGEAAHNFETTPPTDAVSSVLKILRGIYEPQGIEVPDPLQSVCTRWGTDSFSLGSYSHVAVGASGDDYDILAESVGDGRLFFAGEATTRRYPATMHGAFISGLREAANITLHANARAAKSKVEKGPSTNTQACAALLMDLFRQPDLEFGSFSVIFGGQASDPKSPAILKVELGGPRKKGATEGGKADQHHSNKLLFQQLQSHFNQQQQLYVYTLLSRQQAMELREVRGGDEMRLHYLCEKLGVKLVGRKGLGPGADAVIASIKAERNSSRTKTRPSKLKIGIPKSKS
What is the function of this protein?
Probable histone demethylase.
What are the official names of this protein?
Lysine-specific histone demethylase 1 homolog 3, Flavin-containing amine oxidase domain-containing protein 3, Protein FLOWERING LOCUS D-LIKE, Protein LSD1-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: TU91_IOTCI
Sequence: CLSVCSMEYWPVCGSDGKTYPNECHLTSEACMSNTDITVAHVGKCDQ
What is the function of this protein?
Acts as a neurotoxin by inhibiting an ion channel (By similarity).  May also act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature.
What are the official names of this protein?
Turripeptide Ici9.1, Turripeptide OL11-like.
What is the protein family that this protein belongs to?
Belongs to the conopeptide P-like superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OMP2_MYCTO
Sequence: MSWSRVIAYGLLPGLALALTCGAGLLKWQDGAVRDAAVARAESVRAATDGTTALLSYRPDTVQHDLESARSRLTGTFLDAYTQLTHDVVIPGAQQKQISAVATVAAAASVSTSADRAVVLLFVNQTITVGKDAPTTAASSVRVTLDNINGRWLISQFEPI
What are the official names of this protein?
Outer membrane protein MT2024.1.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ENGB_ECOL5
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKTDKLASGARKAQLNMVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ATPH_CICAR
Sequence: MNPIISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEDKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATG12_PONAB
Sequence: MAEEPQTVLQLPPSSAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGPIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
What is the function of this protein?
Ubiquitin-like protein involved in autophagy vesicles formation.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.  The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS.  Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.
Protein: MNMA_ACIB5
Sequence: MQQRVIVGMSGGVDSSVSAALLLQQGYQVEGLFMKNWEEDDGTEYCTAMEDLADAQAVADKIGIKLHTANFAMEYWDRVFEHFLAEYAAGRTPNPDILCNKEIKFRAFLDHAMTLGADFIATGHYARRAETAYNSKGEAYAPLLRGLDNNKDQTYFLHAVHGREINKTLFPVGEIEKPEVRRIAEELDLATAKKKDSTGICFIGERRFNDFLKQYLPAQPGKIVLDNGKEVGEHHGLMYYTLGQRGGIGLGGMKGASEGAWFVLHKDVANNRLVVGQGHDHPLMQSTQLWSEAIDWVAGEQNIPAEGLRCTAKTRYRQPDQACTVFIDENSEHGVRVEFDEPQRAVTPGQSVVFYSDEVCLGGGVIHHTNAPTPNFI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_ACIB3
Sequence: MIDSEGFRPNVGIILANDDGQVLWAKRIGHNAWQFPQGGIQFGETPEQALFRELREEIGLLPEHVQIIAQTKGWLRYRLPHRYIRSDSDPVCIGQKQKWFLLKLTAPAKNIQLNLADPPEFDEWQWVSYWYPLGQVVNFKRDVYRKAMVELCTQLPVQQLP
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: AROD_METMP
Sequence: MICIPVIDKDVSDAINSAKEALKYGDIVEFRIDLLNDVNFKDIEEFSKIPSIITIRAEWEGGAWRKSNEERIELLKNAIKNNAKFIDIELKEEKNLELVKYRNEIGSTTKIIVSYHDFEKTPEIDELIDVVEKELKIGDIAKFATFAHSKEDTLKILNLMNRYSGKIIAIGMGESGKLTRILGLDFGSILTFASMGGKASAPGQVDVKKLKEILKLIN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: HAX1_BOVIN
Sequence: MSLFDLFRGFFGFSGPRSHRDPFFGGMTRDEDEDDEEEEEEGVTWGRGNSRFEGPQSPEEFSFGFSFSPGGGMRFHDNFGFDDLVRDFNNIFSEMGAWTLPSRPPELPGPESETPGERRQEGQTLRDSMLKYPDSHQPKIFGGGLESDARSESSKPAPDWGPQRPFHRFDDTWPVTPHSRAREDNDLDTQVSQEGLGPVLQPQPKSYFKSVSVTKITKPDGTVEERRTVVDSEGRKETTVTHQEAGSSPRDGPESPTPPSLDDSSSILDLFLGRWFRSR
What is the function of this protein?
Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex.  Slows down the rate of inactivation of KCNC3 channels.  Promotes GNA13-mediated cell migration.  Involved in the clathrin-mediated endocytosis pathway.  May be involved in internalization of ABC transporters such as ABCB11.  May inhibit CASP9 and CASP3.  Promotes cell survival.  May regulate intracellular calcium pools.
What are the official names of this protein?
HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1.
What is the protein family that this protein belongs to?
Belongs to the HAX1 family.
What are the subcellular locations of this protein?
Mitochondrion. Endoplasmic reticulum. Nucleus membrane. Cytoplasmic vesicle. Cytoplasm, cell cortex. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Sarcoplasmic reticulum. Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also detected in the nucleus when nuclear export is inhibited (in vitro).
Protein: VG51_BPML5
Sequence: MKKGTKVIVQRDETKHPSKGTWPMFRGRKGVVTCEVRGAGPVEYGVSFSGGDSADAYFKRYELTERK
What are the official names of this protein?
Gene 51 protein, Gp51.
Protein: MUTL_STAEQ
Sequence: MGKIKELETSLANKIAAGEVVERPSSVVKELLENAIDAQATEINIEVEQSGVSSIRVVDNGTGIAQEDLGLVFHRHATSKIVADDDLFHIRTLGFRGEALASISSVAKVTLKTCTDNENGHEIYAENGKIIHQKPAKAKKGTDIQVDSLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPEIRISLVSDGKKLLSTNGSGRTNEVMAEIYGMKVAKDLVHISGDTSDYHLEGFVAKPEHSRSNKHYISIFINGRYIKNFVLNKAILEGYHTLLTIGRFPICYINIQMDPILVDVNVHPTKLEVRLSKEDQLYDLIVTKIREAFKDKILIPQNDLNHASKKNKVLETFEQQKINFEKQQSQIGETSAPYVHDQKDKNHDVESHKNNLDSTSSTNNESTEVSNELHNHIDDSYLQSQKEVLFDMEQNTSNEYEISNQQSNDIKGTVSQTPHRRVPYMEIVGQVHGTYIIAQNENGMFMIDQHAAQERIKYEYFREKIGEVTNEVQNLLIPLTFHFSKDEQMIIDQYKDELDKVGVHLEHFGGHDYIVNSYPVWFPKEEAEEIIKDMIELVLKHKSVDVKKIREDAAIMMSCKKSIKANHYLKNNEMADLIDQLREAEDPFTCPHGRPIIINFSNYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SYT_BUCAI
Sequence: MPVIRFYDGSQQVYEHSVSLIEIIKNKKPSIMKSLIAISVNNHFSNLNTFIREDAFIEFVDQKNYKALNIIRYSCAQLLSYAIKNIWPLAQIATSNIIEDGFYCDIDFKRSISEKDLILLENQMKMLVKREYNILNKLISYSEAREIFQKCFEKYKVSLIDENINCNSKVSLYYHENYADIDIGLQVFNIKFCKYFKLQKIGGVYWKKNKNNKMLQRIYGTAWTNKQELDKHLDYLNELEKRDHRKIGKFLQLYHMQEESPGMIFWHNKGWIIFNELQNFVRVKLKEYKYEEVKTPLLIDKLIWKQSGHWDNYKNAIFTTLSEHREYCIKPMNCPGHVQIFNSRLKSYRDLPIRMAEFGSCHRNEPSGSLHGLMRVRNFTQDDAHIFCTREQVRSEINDCIKMIYDLYSTFHFKKILVKLSTRPEKRIGTDSLWNESEKDLSDMLIENHLSFEYQSGEGAFYGPKIEFILQDSLDRNWQCGTIQLDFYLPLRLSSFYINEKNEKKVPVIIHRAILGSIERFIGILIEECSGNLPTWLSPVQVVIISITDISSGYVKELFKKFSDVNIRIECDLRNEKIGFKIREHTLRRIPYILICGEKESSSKKISVRNRQGHNFGMIDVDFFIKKLQKEIITRNFYQMEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BACC0
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LOVA_ASPTN
Sequence: MTVDALTQPHHLLSLAWNDTQQHGSWFAPLVTTSAGLLCLLLYLCSSGRRSELPVFNPKTWWELTTMRAKRDFDANAPSWIESWFSQNDKPIRFIVDSGYCTILPSSMADEFRKMKELCMYKFLGTDFHSHLPGFDGFKEVTRDAHLITKVVMNQFQTQAPKYVKPLANEASGIITDIFGDSNEWHTVPVYNQCLDLVTRTVTFIMVGSKLAHNEEWLDIAKHHAVTMAIQARQLRLWPVILRPLVHWLEPQGAKLRAQVRRARQLLDPIIQERRAERDSCLAKGIEPPRYVDSIQWFEDTAKGKWYDAAGAQLAMDFAGIYGTSDLLIGGLVDIVRHPHLLEPLRDEIRTVIGQGGWTPASLYKLKLLDSCLKESQRVKPVECATMRSYALQDVTFSNGTFIPKGELVAVAADRMSNPEVWPEPAKYDPYRYMRLREDPAKAFSAQLENTNGDHIGFGWHPRACPGRFFASKEIKMMLAYLLIRYDWKVVPNEPLQYYRHSFSVRIHPTTKLMMRRRDEDIRLPGSL
What is the function of this protein?
Dihydromonacolin L monooxygenase; part of the gene cluster that mediates the biosynthesis of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR) (PubMed:10334994, PubMed:12929390, PubMed:21495633).  The first step in the biosynthesis of lovastatin is the production of dihydromonacolin L acid by the lovastatin nonaketide synthase lovB and the trans-acting enoyl reductase lovC via condensation of one acetyl-CoA unit and 8 malonyl-CoA units (PubMed:10334994, PubMed:10381407, PubMed:19900898, PubMed:22733743).  Dihydromonacolin L acid is released from lovB by the thioesterase lovG (PubMed:23653178).  Next, dihydromonacolin L acid is oxidized by the dihydromonacolin L monooxygenase lovA twice to form monacolin J acid (PubMed:12929390, PubMed:21495633).  The 2-methylbutyrate moiety of lovastatin is synthesized by the lovastatin diketide synthase lovF via condensation of one acetyl-CoA unit and one malonyl-CoA unit (PubMed:19530726, PubMed:21069965).  Finally, the covalent attachment of this moiety to monacolin J acid is catalyzed by the transesterase lovD to yield lovastatin (PubMed:10334994, PubMed:17113998, PubMed:18988191, PubMed:19875080, PubMed:24727900).  LovD has broad substrate specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptopropionate (DMB-S-MMP) as the thioester acyl donor, and can also catalyze the reverse reaction and function as hydrolase in vitro (PubMed:19875080).  LovD has much higher activity with LovF-bound 2-methylbutanoate than with free diketide substrates (PubMed:21069965).
What are the official names of this protein?
Dihydromonacolin L monooxygenase LovA, Dihydromonacolin L hydroxylase, Lovastatin biosynthesis cluster protein A, Monacolin L hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: MURC_RHIL3
Sequence: MKLPKTIGLVHFIGIGGIGMSGIAEVLHNLGHKVQGSDQADSANVQRLRDKGIEVFVGHRAENLGEAEVVVVSTAIKKSNPELIAAREKLLPVVRRAEMLAELMRFRNAIAIGGTHGKTTTTSLVATLLEAGGLDPTVINGGIINAYGTNARMGEGEWMVVEADESDGTFLKLPADVAVITNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQSLVGRIEDRKIITYGENPQADVRFKNVRIDGTRSIFDVEIRRRRTGQVIELKGLVMPMPGRHNISNATAAIAVANRLGISSADIAKGLASFGGVKRRFTLTGEWNGVQIFDDYGHHPVEIKAVLRAARESCKGRVIAVHQPHRFSRLASLFEEFAACFNDADSIFLAPVYAAGEDPIEGIDSVSLVSRIKSGGHRDARFLTSAEFLPQMVAEVAKPGDFVVLLGAGSITSWAAALPKQLEGLSGKSV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBL_MLVCN
Sequence: ASAGGGCRRGPSFSPGSIPSLAAERAPDPPLAMAGNVKKSSGAGGGGSGGSGAGGLIGLMKDAFQPHHHHHHLSPHPPCTVDKKMVEKCWKLMDKVVRLCQNPNVALKNSPPYILDLLPDTYQHLRTVLSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPHFS
What is the function of this protein?
Induces early B-lineage lymphomas.
What are the official names of this protein?
Transforming protein cbl.
Protein: CARB_HALOH
Sequence: MPINKKIKKVLVIGSGPIIIGQAAEFDYSGTQACKALKEEGLEVVLVNSNPATIMTDTDIADQVYLEPLTFDYITRIIEKEKPDGLLPTLGGQTGLNLAVELAEKGVLDKFGVTLLGTNLEAIQKAEDRNLFRELLDDIGEPFIESKIVDNLKEAVQTAQQIGFPVIVRPAYTLGGSGGGIAENVEELKEIVTLGLKRSRINQVLIEKSLYGWKELEYEVIRDGNDNCITICNMENIDPVGIHTGDSIVVAPSQTLSDKEYHLLRMASIKIIKALGIEGGCNIQFALDPEGLDYYVIEVNPRVSRSSALASKATGYPIAQVSAKIALGLRLDEIKNIVTGKTYACFEPALDYVVTKIPRWPFDKFSKGDRSLGTQMKATGEVMAIGRNFTESFLKAIESLDIRLPDFMEDLDRESLENRVKKAYDDRMFYILQAFYNGVKPEDLYEWTGIDPFYLYKIEEIVRLSLKISSNKDKILKGEVNLLARAKKLGLSDSMLGRLLGIPDFEVRDLRLKYGIKPTYKMVDTCAAEFAAETPYYYSTYEEEDEVEVSDNRKVLVVGSGPIRIGQGIEFDYCSVHAVRALQDRNVEAIIVNNNPETVSTDFDTSDKLYFEPLTTEYVLNVAEREGITDVILQFGGQTAINLAEPLSEAGMNVLGTGLKSINLTEDRKQFNQVLTSEKIPTPPGYTVFSIEEALKLSHKIGYPVLVRPSYVLGGRGMEIVSNEAELKTYLTDAVKITPEHPVLIDRYIPGREIEVDAISDGNDVLIPGIMEHVERAGVHSGDSMAIYPARNLTTKQTRRLVNYTKKICNLFGIKGIINIQFVLDRDGQFYVLEVNPRASRTVPILSKVTGIPMVKWSVRIMLGETLNQITTLKGLVPPGDLISVKVPVFSFDKLLGVDIHLNPEMKSTGEVLGTAENLEQAIYKGLKAADFDLPEGGKVLFSLADRDKQEALGVVCRFIEEGYQVLATRKTALYFQKRGLRVEKTEDPVGLIKKGDIKMVVNTPTRGKEPGRIGFKLRRIAVEHNIPCFTSLDTVEMVLQALVRVGEEEKKEVIPLSEYKKGGVLV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: ACPS_BURM1
Sequence: MAIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRALQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVIAETGLPAPDAPTAVSRTTP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPHA3_RHOJR
Sequence: MALTKICSSGDLAPGEMLRFEEGPEPILVCNVGGEFFATQDTCSHADWALSEGYLEDDVVECTLHWAKFCVRTGKAKALPACVPLRTFVVKLEGDDVLVDLEGGVTT
What is the function of this protein?
Ferredoxin component of the biphenyl dioxygenase system that catalyzes the stereospecific dihydroxylation of the aromatic ring of biphenyl, yielding a dihydrodiol compound.  Is likely involved in biphenyl degradation that allows growth of Rhodococcus sp.  strain RHA1 on biphenyl as the sole source of carbon and energy.  The dioxygenase system can also use naphtalene and 4-chlorobiphenyl (4-CB) as substrates, as well as some polychlorinated biphenyls (PCB) such as 2,2'-dichlorobiphenyl, 2,3-dichlorobiphenyl and 2,5,2'-trichlorobiphenyl.  It exhibits weak activity toward dibenzofuran and dibenzo-p-dioxin.  Electrons are transferred from NADH to the [2Fe-2S] cluster in BphA1 via FAD of BphA4 and [2Fe-2S] cluster of BphA3.
What are the official names of this protein?
Biphenyl 2,3-dioxygenase, ferredoxin component, Biphenyl 2,3-dioxygenase, electron transfer component BphA3, Biphenyl dioxygenase system, ferredoxin component, BDO, ferredoxin component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.
Protein: RNZ_TREPS
Sequence: MHMNLEAFILGCGGMVPLPHRHLTSVLLRREGELFLFDAGEGTQVSLRRLSLRWKKISAIFISHTHADHITGLPGLLMLSSQVARSEPLYIIGPPRTAEYVETSRRILDMYINYEIIVKEVIEPQVVYRGKDFQVRCFCLDHTKPCMGYTLEEQDRPGSFDPRAAQDLHVPCGALWSQLQSGVAVQSAQGVTVYPEQVMGPARPGRKVSFVTDTKYLQSIAAEVRNSDFFVCEGMFEKGMEKDAAEKKHMTCVQAATIARDARVRLMALIHYSPRYTDHELKRLLKEAQRVFPHTILSRDQLMVPIAYRE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.