PharMolix/UniProtQA huggingface dataset:
Protein: HBSAG_HBVB3
Sequence: MGGWSSKPRKGMGTNLAVPNPLGFFPDHQLDPAFKANSDNPDWDLNPHKDNWPDANKVGVGAFGPGFTPPHGGLLGWSPQAQGLLTTVPAAPPPASTSRQSGRQPTPLSPPLRDTHPQAMQWNSTTFHQTLQDPRVRALYFPAGGSSSGTVSPAQNTVSAISSTLSKTGDPVPNMENISSGLLGPLLVLQAGFFLLTKILTIPQSLDSWWTSLNFLGQTPVCLGQNSQSQISSHSLTCCPPICPGYRWMCLRRFIIFLCILLLCLIFLLVLLDCQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKFLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWFWGPSLCNILSPFMPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: THI42_MAIZE
Sequence: MATTAASSLLKSSFAGSRLPSATRTTTPSSVAVATPRAGGGPIRASISSPNPPYDLTSFRFSPIKESIVSREMTRRYMTDMITHADTDVVIVGAGSAGLSCAYELSKDPTVSVAIVEQSVSPGGGAWLGGQLFSAMVVRRPAHLFLDELGVGYDEAEDYVVVKHAALFTSTVMSRLLARPNVKLFNAVAVEDLIVRRGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLQDIGMISAVPGMKALDMNAAEDEIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGRPNAVDGTIPEVSPALREEFVIASKDDEVVDA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase 2, chloroplastic, Thiazole biosynthetic enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: TBX6_RAT
Sequence: MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAPPPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPVATEACGSGDTPGGPCDSTLGGDIRDSDPEPAPTPQEAASASAPPCGGPSAEAYLLHPAAFHGAPSHLPARTPSFPEAPDPGRPAPYSAAFLELQPGPGSSAYQTTPSVTPFAPHFIQGAPFPLPYPGPGGYLDMGSKQMY
What is the function of this protein?
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal.  Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development.  Seems to also play an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
What are the official names of this protein?
T-box transcription factor TBX6, T-box protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y096_ARCFU
Sequence: MVFLHIMLATWGLHMSFYVKKLSSPQNYFEITEEDFREIPKLKEIFVDLQKLAPGEERSYELDFSTGNKISEYLTEKQAEVGECGYTYCFKYGDAYYGAHMGTP
What are the official names of this protein?
Uncharacterized protein AF_0096.
Protein: RS2_AZOSB
Sequence: MTVTMRQMLEAGVHFGHQTRFWNPRMAPYIFGQRNKIHIVNLEKTMVKYNEAMNFVRKLAANRGTILFVSTKRQAREILAEEARRAGMPYVDERWLGGMLTNFKTVKQSIKRLKEVEAMIEDGSIERLSKREALTVTRELEKLQKSIGGIKDMGGLPDAIFIIDVGYHKIAVTEAQKLGIPVVGVVDTNHSPEGIDYIIPGNDDSSRAIRLYARGVADAVLEGRSQVLQEIVAAGGDEFVEVEEGSQEQQG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RHDF1_DROME
Sequence: MSSNGSDLGHNNRRNEKGNPDSVHSSMRGSMSSTRRKSINFQNQLQLALESNECDVMYCSLSSGRFRAPNGENFPPHGGKLKLSPLEKYDDANRGVPPPSPAPNSDCFATCVANQLPSQSCSVGSAKPETSVMQKHGMAGNGMVGSGMSGNGMAANGTNYHQRGVSPNSRYRLERYRESQSTPQSKLMDNMGGMPSAVPSVSATRLLLPSNVPLPLAQCENYNAYLGSTVHTPVKRYVPTPPPAMELYSDLSISSSPAANLPTPAAAVASSASTSASAMQSQYANMPYNYRSKCCHSEASHGSLSRTSQTYASCSPACTSPSPAPSTSMSMVFSAASSCSPIMTATSSARSGNHRGDDSDSVIVVPPGGGAMAQIEAENPSGTCLHCNTVRRTTGVHQTTQTTGPISPVPISLPVPMAMPVMSGLNEQMPSQSLESSMVSVQAKRLEGGGNMAVPPGSNQHQLYRSQMASNPRLQHIHHQTQQHQSLQVLPQPQNHHLSCKKRIGMYMRRTTSQFFGVEPSTEAADCALWQGRHRRLAIRCFGMFDTELEYHMQQAIGGGNEDAGQSNGTNGNYAPDRPDILPVQDAIGMDMTMSGDSRRQKCYTNRDFLAGEFVERKASVGYMFVAMVSYLVHMFNKRRPIQMHRVRCPWQWSRSFAPIHVQSHSNQQTDADGCLTDGLEAIIDDEVFFDSPCEITTSAVNDESSDIGRQAAKPRPCADQSGVGVSVYMAERQQNGWRTSALNSGGNATSDINLTGDQSSHQPGAAHIPLCSSVSSQMQPAMRSSHSTTSTCNRGNRITAQLLDGVLENSRRPPLRCIKYFSVNDLDDRTDHRPFFTYWINTVQVVVLILSIICYGIAPIGIGSEQKTGQVLVTSLSLQTVQHVEQRNLWIGPRNIDLVHMGAKFAACMRRDIKITEVVTKTRRHERETACCIRNDDSGCVQSSQAECSIRGLYPTKSISTWKKWSPSESGPGGRISGSVCGLDPKFCDAPASIAPYEWPDDITKWPICRKTNSFTQRYRYKDHTSEHMVCEVIGHPCCTGLYGECRITTREYCDFIKGYFHEEASLCSQISCLNNVCGMFPFISVETPDQLYRLLTSLCMHAGILHLAITLIFQHLFLADLERLIGTVRTAIVYIMSGFAGNLTSAILVPHRPEVGPSASLSGVVASLIALLVWMHWKYLHKPHIALFKLLLLCSVLVGIGTLPYQLNFLGLLAGVICGCLLTMSLVPFTTFSKYGRKKKINLIWTCVLFHVVVYTAMIVTFYIHPSEFHSISFVDMFSNSNGYDNFTNADHHGVDVVSSNTRYSQTQNSQYYYHHHSDDIIRKSVTFTEKALVSHILYPTAPRKTSAQQWQEVEYSRSFNHLSNYSDRIKKSIGNISKLKQVFTSPIRFSNKNNHSNLMTELTSVHSENKQKYLGYINNNTEFNVL
What is the function of this protein?
Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor.  Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration.
What are the official names of this protein?
Inactive rhomboid protein 1, iRhom, Rhomboid family protein rhomboid-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TMEDE_DROME
Sequence: MRDQFISLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV
What is the function of this protein?
Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo.  Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected.  Involved in Golgi organization.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein eca, Protein eclair.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PRVA_RABIT
Sequence: MAMTELLNAEDIKKAIGAFAAAESFDHKKFFQMVGLKKKSTEDVKKVFHILDKDKSGFIEEEELGFILKGFSPDARDLSVKETKTLMAAGDKDGDGKIGADEFSTLVSES
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin alpha.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: UBIB_SHEPW
Sequence: MTVKSIKRAYQVIRTTLHYGLDDLIPSKVTPWYFKLLRGSLFWLRNKHKDKVGGERLKLAMQELGPVYIKFGQMLSTRRDLLSDEWAEELAMLQDRVPPFDSAIARESIEQELNAPIETYFDDFEDTPLASASISQVHTATLKSNGAKVVLKVLRPDVEQKVHADIQLMSQAANFLESLLGANNRLRPAEVVEDYRTTIEGELNLKLEALNAIKLRNNFLDSNALYIPYMYEELCFTRLIVMERIDGVPVSDKAALEAQGTNLKLLAERGVELFFTQVFRDNFFHADMHPGNIFVSREHPNDPFYIGLDCGIMGTLTDEDKRYLAENFLAFFNRDYRRIAQLYIESGWVSADTDISAFEQAVKVVCEPMFNKPLDEISFGHVLLELFRTARRFDMVVQPQLVLLEKTLLYIEGLGRQLYPQLDLWQTAKPFLEDWMAEQVGPKAMAGKIKQQLPYWADQLPELPELIYDNLKMGRNLAKTHNKLLDRYLKHQQKAHKSNYLLITSAILVICGTILLNQDATLWASYGSIGTGLILWVLGWRSRPKNRKF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM1_ECO27
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQEASEFMAWLRAQSASETIRDYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NADK_LIMRJ
Sequence: MRIGIYNNETAESQRVTKVLKTEMKRAGLTYVEKNPEVVITIGGDGTLLSAFHHYQKDLNNIRFVGIHTGHLGFYTDWRSFEIDDLVDSLVKDSGQAVSYPLLDMKATYSDGQIENYIALNESTIRNVTRTMVCDVFINNHLFENFRGDGLCISTPTGSTAYNKSVGGAIVDPNSVGFQLAEMASLNNRVFRTLGSPIIFGADAELILRLRDENGHVLTCDRDQWMLKSEKERYLTELSYKVSKQRIYFAQYRHNNFWNRVKDSFIGGVH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_DROMO
Sequence: MVDNLPPLEPSLQNLVEQESLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKVPTKVNGFDNLFAMEIDPNAGLGELPDEYFEGENEALRVSKGVMQEMINALPGIDEAMSYAEVMKLVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKLAPLLSQFVSMLGMADVNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNIIVNQLLFLDKSHNSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIKSFSENLMIPYKPKE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: KLEB1_ECOLX
Sequence: MSKGKIEIIETCCRRCGKSIRTLSHTIIGADDAREKFGSICGGCITPEEDNELTEMLLAAAVRRMSGATLQ
What are the official names of this protein?
Protein KleB, KcrA2 protein.
Protein: CSYB_ASPOR
Sequence: MIEPLPTEDIPKQSVSIVGIASRCAPHKLGADELEAIARRHYSSTPSLEKMLEINRKTRIDHRYSVFSSDHEHWHRPTIPSFSECDSLFKEYGIPLASAASARAIQDWGGVPDEITHLVAVTCTNTAHPGFDSVLCRKLGLKCNVRRVLLHGIGCGGGISAMRVAHELLLGSTQQGVPARALIVACEVPTVFARSELDIMDKTQDVNVAMCLFGDCAAALVLSNGIGHKASEQRPIWNILNCEPTQFDGTEDIAHFNVHDKGYHAIIDKRIPQLTGKCVPAGFQSLISSTPSLALEEKNYVPSNYGWAVHPGGYAVLVAAQDALGLTADDLRASYDAYRDGGNTISTTIIRILEKLRDEHKHGSNQKDKLVLAAIGHGITLETAILTRPGSSSYLHA
What is the function of this protein?
Acylalkylpyrone synthase that catalyzes not only the polyketide chain elongation but also the one-pot condensation of two beta-ketoacyl units to produce the 3-acyl-4-hydroxy-6-alkyl-alpha-pyrone (AcAP) scaffold, a precursor of csypyrone B (PubMed:20471846, PubMed:23290452, PubMed:24011646, PubMed:24895122, PubMed:25564614) (Probable).  The enzyme reaction is initiated by the loading of acetoacetyl-CoA onto Cys-155, and subsequent thioester bond cleavage by the nucleophilic water generates the beta-keto acid intermediate, which is placed within a pocket (PubMed:25564614).  The second beta-ketoacyl unit is then produced by polyketide chain elongation of fatty acyl-CoA with one molecule of malonyl-CoA, and the condensation with the beta-ketoacid generates the final products (PubMed:24895122, PubMed:25564614).  Csypyrone B1 is the major product and contains a propanoic acid side-chain, whereas csypyrones B2 and B3 are minor compounds that contain butyric or pentanoic acid side-chains, respectively (PubMed:20471846, PubMed:23290452, PubMed:24011646).
What are the official names of this protein?
Acylalkylpyrone synthase csyB, Type III polyketide synthase csyB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PCKA_BACTN
Sequence: MANLDLSKYGITGVTEIVHNPSYDVLFAEETKPGLEGFEKGQVTNMGAVNVMTGVYTGRSPKDKFFVKDETSENTVWWTSEEYKNDNKPVDAKCWAAVKDLATKELSNKRLFVVDAFCGANENSRLKLRFIMEVAWQAHFVTNMFIRPTAEELANFGEPDFVIMNASKAKVENYKELGLNSETAVVFNLTEKIQVILNTWYGGEMKKGMFSYMNYLLPLNGMASMHCSANTDKEGKSSAIFFGLSGTGKTTLSTDPKRLLIGDDEHGWDDEGVFNFEGGCYAKVINLDKESEPDIWNAIKRDALLENCTVNAEGEINFADKSVTENTRVSYPIYHIENIVKPVSKGPHAKQVIFLSADAFGVLPPVSILNAEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTKYGEELVKKMEKTGAKAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIDKAPTKVMPYFDFVVPTELPGVDPKILDPRDTYECACQWEEKAKDLAGRFIKNFAKFTGNEAGKALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_MANSM
Sequence: MAKTIKVTQVRSSIARLPKHKATLRGLGLRHMHHTVELIDTPAVRGMINQVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GCS21_COREF
Sequence: MAIEFKRSPKPTIGVEWEIALVDPESRDLAPRAAEVLEIVAERHPEVHLEGEFLQNTVELVTGICDTVPEAVAELDRALAAVQEAATELGLRPWTSGSHPFSDFRENPVSKKGSYDEIIARTQYWGNQMLIWGIHVHVGISHEDRVWPIINALVTNYPHLLALSASSPAWDGLDTGYASNRTMLYQQLPTAGLPYQFQSWDEWVSYMADQDKSGVINHTGSMHFDIRPASKWGTIEVRIADSTSNLRELSAIAALTHCLVVHYDRMIDRGEQLPTLQPWHVAENKWRAARYGLDAEIIISRDTDEAMVQDELRRLVDRLTPLAAELGCLRELDLVLEIIERGGGYERQRRAYQRTGTWIAAVDLACDELNELRPLEAE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: UPPP_PHOV8
Sequence: MEWFEALILGVLQGLTEYLPVSSSGHLAIGSALFGIQGEDNLTFTIAVHVATVLSTLVILWKEIGWIFRGLFKFEMNAETKYVINILVSMIPIGIVGVFFKDYVEEIFGSGLLIVGCMLLLTALLLAFSYYAKPRLKENISMKDAFIIGLAQACAVMPGLSRSGTTIATGLLLGDNKAKLAQFSFLMVIPPILGEALLDGMKIVKGAAAGTSDISVLSLVVGFLAAFISGCVACKWMINIVKKGKLIYFAIYCAIAGAVTIACTLM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DLDH3_PSEAE
Sequence: MMESYDVIVIGAGPGGYNAAIRAGQLGLKVACVEGRETLGGTCLNVGCMPSKALLHASELYAAASGGEFARLGIRVSPELDLAQMMKQKDESVAALTRGVEFLFRKHKVQWIKGWARLQGEGRVGVALADGGHAQLEARDIVIATGSEPAPLPGVPVDNQRILDSTGALELVEVPRHLVVIGAGVIGLELGSVWRRLGAQVTVLEYLERICPGLDGETARTLQRALTRQGMRFRLGTRVVAARSGEQGVELDLQPAAGGATESLQADYVLVAIGRRPYTEGLGLETVGLASDRRGMLENQGQRSAAPGVWVIGDVTSGPMLAHKAEEEAIVCIERIAGHAAEMNAEVIPSVIYTQPEVASVGLGEEQLQAARREYKVGRFPFSANSRAKINHESEGFIKILSDARSDQVLGVHMIGPGVSEMIGEACVAMEFSASAEDLALTCHPHPTRSEALRQAAMDVHGRAMQN
What is the function of this protein?
LPD-3 may substitute for lipoamide dehydrogenase of the 2-oxoglutarate dehydrogenase and pyruvate multienzyme complexes when the latter is inactive or missing.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase 3, Dihydrolipoamide dehydrogenase 3, LPD-3.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_HERAR
Sequence: MAELATIARPYAEALFRVAKAADLNGWSELVSEMAQVAAHPDVYALAHNPKISDDVISSAFISALKSPVGAEAKNFINMLVQNDRLTLLPEIATQFHALKNAQEGAADAEIVSAFELSAAQLTELVATLEKKFGRKLNPTVAVDSALIGGVRVVVGDEVLDTSVRAKLQQMQVALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FAEHP_METPE
Sequence: MYQIGEALVGDGAELAHIDLIIGEKSGPVGIAFANGLSQLSAGHTPLLAVIRPNLLTKPATLIIPKVTLKNQTQVTEMFGPVQAAIAKGIADCIEEGTFKEYDIEDLVILASVYLAPEAKDYNKIYRYNYGAIKLALNRALEGFPPEKTILYEKDRGAHAVMGFKVQRLWDAPYLQVAMDLVDMGKVAKVLKEVPDNDHVIIEAGTPLIKRFGLSVISEIRKLRPNAFIIADMKILDTGNLESRMAADASADAVVISGLAPASTIEKAIEETKKTGIYSIIDMLNVPNPVELIASLKIKPDIVELHRAIDCETSCHAWGDIVAIKKAAGGKLLVATAGGVRVEVVKEALASGADILVVGRAITASKDIRHATEEFLEQLHKDEIDQFRVMTDF
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: GLK_BRUSU
Sequence: MQAIIDAEQSFKFPVLVGDIGGTNARFSILVDSNAEPKEFPVLQTADYATIDEAIQHAILDQTAIQPRSVILAVAGPVDGDEIDLTNCDWVVRPKKMIADLGFEDVTVLNDFEAQALAVVSLEGHHMEQIGGKPEEAVATRVVLGPGTGLGVAGLVRTRHAWVPVPGEGGHIDIGPRTERDYQIFPHIERIEGRVTGEQILSGRGLRNLYLGICAADKITPTLETPVDITSAGLDGSNPQAAETLDLFATYLGRLAGDLALIFMAHGGVYLSGGIPVRILSALKAGSFRAAFEDKAPHKAIMRDIPVRVITYQLAALTGLSAFARTPSRFEVSTEGRRWRMRR
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNK_BACAA
Sequence: MGYYSLTEVTAVQYAKEHGYFEKKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAKYVPEYVPVVYSHDEELAVTVIEDLSRLTITRKGLIDGEEYPLLSQHIGRFLANVLFYTSDFGLQSEEKRVLEGTFVNPDLCKITEDLVFTDPFGHYDTNDYEPELQLTIDELWSDKTLKLKVAQYKYKFLTRKEALIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQFIANLLLNALSREEEQRGVLFFHIEKTWSYFVETFTKLWIGEGVEAYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDEITNKETRIQAKKQALSLGKELIKYESKNADIQLFRTLFQQTVSGGIKA
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: CASP1_MEDTR
Sequence: MKGGSIELGEVSKNASTNKGVKRGLSIMDFILRIIAGVATLASAVAMGTTDERLPFATSFVQFRAEYDDLPSFVFFVLANSIVCGYLALSLILSILHIVRSTAVKSRILLIVLDMVMMGLLAAAASAAASIVYIAHYGNTQANWFPICQQYNSFCERISGSLIGSYIAVALFIIIILLSQSAISRN
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, MtCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: FUB7_GIBM7
Sequence: MAEQVFQNFETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVFEKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLFPRFGIKTKFVRSGKLEDYVAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLGAGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSDRFPEMVEPSPSYHGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLAKYFESSPNVSWVLWPGSESHPTYAQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVSNLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQSFQKAYGA
What is the function of this protein?
Sulfhydrylase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:25372119).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the O-acetylhomoserine FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity).
What are the official names of this protein?
Sulfhydrylase FUB7, Fusaric acid biosynthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: RSMH_BUCAI
Sequence: MNHIFKHIPVMKKELIDSLKIKKNGIYIDSTFGTGGHSNEILKKLGQNGRLYSIDRDPIAFSIGSEIKDSRFHIINENFSKLLDFAKNEKIIGKVNGIIFDLGVSSIQIDDYRRGFSFKNDGPLDMRMNPNYGISASEWLFESNVKEISFVLKNFGEERFSRKIAYAIKRRSQIKKITSTLELANIIKKTIPTKNKFKHPARRSFQAIRIYINQELEEIQKALESTLKILKPGGRISIISFHSLEDRLVKKFMIKNSTKAIIPYGMPITEEQLNRLTTCKLKIINRILPTQNEINNNPRARSSVLRIAEIQE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.