PharMolix/UniProtQA huggingface dataset:
Protein: PDX1_GINBI
Sequence: MASDGVVTVYGDGAITDTKVSSYAVKVGLAQMLRGGVIMDVVNAEQARIAEEAGATAVMALERVPADIRAQGGVARMSDPGLIKEIKSAVTIPVMAKARIGHFVEAQILEAIGIDYIDESEVLTPADDXHHINKHNFRIPFVCGCRNLGEALRRIAEGAAMIRTKGEAGTGNVIEAVRHVRSVLGDIRKLQSLDDDEVFAFAKQIAAPYELVRQTKQLGRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGVFKSGDPARRARAIVQAVTHYNDPHILAEVSCSLGEAMVGINLKDEKVERYAERSE
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by PDX2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.  Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit PDX1, PLP synthase subunit PDX1, Sor-like protein.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: ACT3_DIBDE
Sequence: MAFNEDVGALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIVFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDMAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMSNAASSSALEKTYELPDGQVITIGNERFRCPEALFQPNFLGLESVGIHETTYNSIMKCDLDIRKDLYANTVLSGGSTMYPGIADRMQKEISALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPAIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-3.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ENO_TREPS
Sequence: MSDIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGKGVLKAVGTVNTLIADTLEGMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACARAAADFLGVPLYRYLGGVHTFRMPVPMANIINGGKHSDNKIDFQEFMVMPIGAASMREAVRMTAEVFHALKGLLAADGKATSVGDEGGFAPDLDNEQALEYIMKAIAKAGLAPRKDVCIALDCASSELFDEGDRRGYKFWKSNPGKLFTAQEMIDLYKKWIATYPIVSIEDPLDQNDWAGYVQLTKELGDKVQIVGDDFFVTNTGRLARGIKEGSCNSILIKLNQIGTVTETVDAVRMAQNAGYAAVISHRSGETEDAFIADLAVALETGQIKTGSMSRSDRVAKYNQLMRIEEELGAQARYYGAKTFERFGC
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PIGM_CHICK
Sequence: MAGGRPGLRAALGAGLLARLSLVLYGLYQDAVMRVRYTDVDYRVFTDAARLVTQGRSPYRRATFRYTPLLAWLLTPNVHLGELFGKLLFVAGDLAAAGVAYRALRRRGASPGRACGCCAAAWLLNPLPMAVSSRGNAEALVAVLVLAALHLVEAGSVGRAALCYGLAVHLKIYPLTYALPIALRLQGSGEGAAGAGRDGTAEFTLVGGIWRRVVRVLNRNVLLFGAVAGSVLAALTVLFYHLYGWEFLEHAYLYHLTRRDIRHNFSPYFYMLYLTAESKWSFALGLAAFLPQLLLLLVVSVAFYKDLFFCCFLHTAIFVSFNKVCTSQYFIWYLCLLPIIIPNIKMSWRRGVLLLFLWFAGQGLWLAPAYLLEFKGYNTFVFIWSAGLLFLFINSFILVQIISHYQQETQVARKVKEQ
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Phosphatidylinositol-glycan biosynthesis class M protein, PIG-M.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y819_PYRHO
Sequence: MKVMKILLVLPPTESAIKRVVGTTGPPLGLAYLASMVREEHDVKIIDGLAEDLTFSDIAKIIKKFDPDIVGITATTSAMYDAYTVAKIAKNINENVFVVMGGPHVTFTPELTMRECPCIDAVVRGEGELTFKELVDALSKGRELKGILGLSYKENGKVRNEPPRPLIQNVDEIPIPSYDLLPMDKYKADGVPFGVVMTSRGCPFNCVFCSSSLQFGKRWRGHSVERVIEELSILHYEYGIKEIEFLDDTFTLNKKRAIDISLRIKQEGLDISWTASSRVNTFNEKVAKAMKEGGCHTVYFGIESASPRILEFIGKGITPQQSIDAVKTAKKFGLHALGSFIIGFPDETREEVEATIKFAKKLDIDYAQFTIATPYPGTRLWEYAIANNLLLTMNWRKYTTIDPVMKLKHFTSEQISKLLRKAYISFYLRPKVLIKDIFEHHGFIIKRAIRGLLRVYYQA
What are the official names of this protein?
Uncharacterized methyltransferase PH0819.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: UL117_HCMVA
Sequence: MVMFSQDHVQIVYGSTRICKSLAPANKRKTHRTIVVAPRRGFLRIPPDGQDVNHVKIVPTTSSSLAPPRDDERRPTPPLRPPLTVYPYGTSLIRRSARDAKLRSKLIVFHITRPALGQHPQNPGISGPAAMDHSEFLTSFRREVDRQTVLTAESAPATAEVCLGDALPGGVMGGGGLPAGVGSASAAVAAAAAAVAGVPVAANPVMPATATVTTPPMIDLTSHHRPLTLFTPASAAAAPAVATNGGNATYILPADCRYAPLFASKYKYVFEEVSRLMRLHDSTAVQLQISASCGNAFQALKSALLKLHNVTVLAGQQLITQTMPHTPQAVATFKFFHQDPNRVLDCIRPVVPRSTSYHETGVYQMWVSGATKKDLFDAVTLCASIVEKQPDVFNINVSLLTYPSIAAPHLPLYNEFTSFRLPTS
What is the function of this protein?
Plays a role in the inhibition of host DNA replication in the infected cell.  Targets the mini-chromosome maintenance (MCM) complex and blocks the accumulation of MCM proteins and their loading onto host chromatin.
What are the official names of this protein?
Protein UL117.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U84 family.
What are the subcellular locations of this protein?
[Isoform UL117]: Host nucleus. Note=The major fraction localizes to nuclear compartments. SUBCELLULAR LOCATION: [Isoform UL117.5]: Host nucleus.
Protein: LV316_HUMAN
Sequence: MAWIPLLLPLLTLCTGSEASYELTQPPSVSVSLGQMARITCSGEALPKKYAYWYQQKPGQFPVLVIYKDSERPSGIPERFSGSSSGTIVTLTISGVQAEDEADYYCLSADSSGTY
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 3-16.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CCMA_ECOLI
Sequence: MGMLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDGDTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVNGVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROH_SALTY
Sequence: MNRTDELRTARIDSLVTPTELAQRYPVSSSVASHVTDSRRRIEKILNGEDPRLLVVIGPCSIHDLNAAMEYATQLQAQRQKHQARLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNYGLELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKDGQMTIYQTSGNPYGHIIMRGGKKPNYHAEDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCDDICQQIRNGSTAIAGIMAESFLREGTQKIISGQPLIYGQSITDPCLNWEDTEVLLEKLAAAVDSRF
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: MT_ANAPL
Sequence: MDPQDCTCAAGDSCSCAGSCKCKNCRCRSCRKSCCSCCPAGCNNCAKGCVCKEPASSKCSCCH
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: THIC_SULIL
Sequence: MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CYPK_STRVN
Sequence: MVQPAATPVSLPSPTVHRSEHTVTVAAPPEALYALVADVTRWPAVFEPTVHVRHLAREGRTERFEIWAEVNGEIAHWRSRRVLDPVRRYVSFRQEHSRPPVTSMSGGWLFRPLADGRTEIVLRHRFTVADDDPAAVARIEEALDRNSARELGALAALAETGHPVDELVFSFTDTLPLQGAARDAYTFVERAERWAELLPHVAQCGADRAGTGLEQWLEMDTVTADGSTHTTRSARICRAPEWIAYNEQRTPRLVSGHSGEWTFAQTPEGPVATARHTVAVDPSGITEVLGPDATLADARAYLRDALGRNSLATLRHAAEAAQRA
What is the function of this protein?
Is needed for correct cyclization of the oligoketide leading to isochromanequinone formation.
What are the official names of this protein?
Granaticin polyketide synthase bifunctional cyclase/dehydratase.
Protein: TREA_SALPC
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGALFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVKKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSHSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASQYDALANARQKAIEMHLWNNKEGWYADYDLQNNKIRDQLTAAALFPLYVNAAAKDRAAKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UREF_BURMS
Sequence: MDTAELVALLHLASPALPIGAFSYSQGLEAALDAPLIRDADGARDWIASGLADVLAQGELPFLAHQLARWHAHDAAALADANDEFVASRESFELRRETEQMGWSLAQLCASLEWGDAARRATLASIPSVALPSAFAFAAAAHGATPDAALAAYAFGWVENQTAAAIKAVPLGQLAGQKIIVALREPIRDAVRRALATPPEAINTFAPQLGILSARHESQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_THEP1
Sequence: MYLQDVIMKLNDFWASKGCLLEQPYDMEVGAGTFHPATFFGSLRKGLWKVAYVQPSRRPTDGRYGENPNRLQRYFQYQVIIKPSPENSQELYLESLEYLGINLKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQIGGISLKDIPLEITYGLERIAMYLQGVDNVYEVQWNENVKYGDVFLENEREFSVFNFEEANVGLLFRHFDEYEKEFYRLVEKNLYLPAYDYVLKCSHTFNLLDARGAISVSQRQTYVKRIQAMARKVARVFLEVQVNENSPA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHB_GLUPO
Sequence: MINRLKVTFSAAAFSLLAGTALAQTPDADSALVQKGAYVARLGDCVACHTALHGQSYAGGLEIKSPIGTIYSTNITPDPTYGIGRYTFAEFDEAVRHGIRKDGSTLYPAMPYPSFSRMTKEDMQALYAYFMHGVKPVAQPDKQPDISWPLSMRWPLGIWRMMFSPSPKDFTPAPGTDPEIARGDYLVTGPGHCGACHTPRGFAMQEKALDAAGGPDFLSGGAPIDNWVAPSLRNDPVVGLGRWSEDDIYTFLKSGRIDHSAVFGGMGDVVAWSTQYFTDDDLHAIAKYLKSLPPVPPSQGNYTYDPSTANMLASGNTASVPGADTYVKECAICHRNDGGGVARMFPPLAGNPVVVTENPTSLVNVIAHGGVLPPSNWAPSAVAMPGYSKSLSAQQIADVVNFIRTSWGNKAPGTVTAADVTKLRDTGAPVSSSGWNSVSSGWSVFLPQPYGSGWTFAPQTHTGQDAAQ
What is the function of this protein?
Cytochrome c component of the alcohol dehydrogenase multicomponent enzyme system which is involved in the production of acetic acid and in the ethanol oxidase respiratory chain (By similarity).  Quinohemoprotein alcohol dehydrogenase (ADH) catalyzes the oxidation of ethanol to acetaldehyde by transferring electrons to the ubiquinone embedded in the membrane phospholipids (PubMed:2001402).  The electrons transfer from ethanol to membranous ubiquinone occurs from pyrroloquinoline quinone (PQQ) to one heme c in subunit I (AdhA), and finally to two heme c in subunit II (AdhB) (By similarity).  Besides ubiquinone reduction, ADH also has a ubiquinol (QH2) oxidation reaction which mediates electron transfer from ubiquinol to the non-energy generating bypass oxidase system (By similarity).  The electrons transfer occurs from ubiquinol (QH2) to the additional heme c within subunit II (AdhB) (By similarity).
What are the official names of this protein?
Alcohol dehydrogenase (quinone), cytochrome c subunit, ADH, Alcohol dehydrogenase (quinone), subunit II, Cytochrome c-553, Cytochrome c553, Ethanol:Q2 reductase, G3-ADH subunit II, Quinohemoprotein-cytochrome c complex, Ubiquinol oxidase.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Periplasmic side.
Protein: KDSB_RHIE6
Sequence: MSDSNLDEVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAKEAAIGRVVVAVDDQQVFDAVSAAGFDVVMTSSDHQSGSDRIFEALTKVDPDGKAKFIVNVQGDLPTIDPQTVRAALRPLENEAVDIGTLTTEIDDEDDKTAPHIVKIVGSPVSDTRLHALYFTRATAPHGKGPLYHHIGLYAYRRAALERFVSLGPSTLERRESLEQLRALEAGMRIDVEIVDTVPLGVDTPADLEKARRILSARTG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTU1_CHICK
Sequence: MLAAGRRVACAVSGGVDSAVAALLLRRRGYQVTGVFMKNWDPLDEQGACSVDRDCEDAYRVCQKLDIPFHQVSYVKEYWNEVFSDLLKEYELGRTPNPDIVCNKHIKFNHFLHYAMDNLGADAIATGHYARTSLEDEEVFQQKHTKRPRELFRNRFEVRNTVKLLQGADLFKDQTFFLSQISQDALRKTIFPLGDLTKSFVRKIASEHGLHHVLKKKEACTTFPFQSMGVCFIGERNFEKFLLEYLEPQPGNFVSIEDKKVMGTHKGWFLYTIGQRARLAGLQGAWFVVDKDVSTGDIFVAPSTDHPALFRDLLRTNRVHWIAEEPPAELVRDKMMECHFRFRHQMALVPCVLTLNQDGSVWVTLVKPARALTPGQFAVFYKGDECLGSGKILRLGPSVFTMQQGRNREEGTKKEDIDKVEPAT
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position.  ATP is required to activate the C2 atom of the wobble base.
What are the official names of this protein?
Mitochondrial tRNA-specific 2-thiouridylase 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UBID_HERAR
Sequence: MKYSDLRDFISQLQQMGELKRINMPVSPYLEMTEICDRTLRAEGPALLFENPTGHTIPVLGNLFGTPQRVALGMGATDVSELRKIGHVLAMLKEPEPPKGFKDMLGLGSLVKSLWDMTPKERRDAPCHDIVWEGNDVDLARLPIQHCWPGDIAPLITWGLVITKGPHKKRQNLGIYRQQVIGRNKVIMRWLAQRGGALDFREHSIANRGQPYPIAVALGADPATILGAVTPVPDSLSEYQFAGLLRGSRTELVKAIGSELRVPASAEIVLEGHIYPDESHPSGYEHALEGPYGDHTGYYNEQDTFPVFTIDRITMRRDPIYHSTYTGKPPDEPAILGVALNEVFIPLLQKQFSEILDFYLPPEGCSYRMAVVQMKKAYPGHAKRVMFGVWSFLRQFMYTKFIIVVDEDVNIRDWKEVIWAITTRVDPTRDTTLVDNTPIDYLDFASPVSGLGSKMGIDATNKWPGETDREWGTTITMTPEVKKRVDQIWQELGI
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIS4_THEYD
Sequence: MQIIPAIDLKDGKCVRLRQGKFSEVTVYYDNPEDAALRWQNEGAEVLHVVDLDGAKEGKIGNLPSIKKIREAFRGNIEVGGGIRRIEDIELLLSVGIDRVIVGTIAVQSPDFVKEVCKRFPKKIIVGIDAKDGLVAVKGWVEVTEIRAIELALKMQDYGIWGIIYTDISRDGMLTGPNIEATKALVESVKVPVIASGGVSSIEDIRKLAEIPQLWGVITGKAIYSGAIDLKEALRIIKGDGVKK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y526_METJA
Sequence: MEVLPLVSGICCILGGIGVILHTNPINKIIMLALLEIGMIGLIVSCYYLDIAIVSSLCEPICTVILLLGYLKYLTTVKKKKRYGRNLPILSK
What are the official names of this protein?
Uncharacterized protein MJ0526.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRA_ECO57
Sequence: MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_RHIEC
Sequence: MTKLENPVLMATIGGAQGLRGEVRAKAYTADPTALGDYGLLHSTDGRSFEILEIREMKNVVVVRFRGINDRNAAEALNGLELYIERDNLPDEELEDDEFYYADLEGLEALDDKGVSYGTVTGVFDFGAGDLLELKGPGKRPVLIPFSEASVLEIDLEAGTLLIDPLAAGLVDDPELSQFTAGKPKKKK
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_GEMAT
Sequence: MAFSATQIRRGMVLVFEGDPCRVIEFRHHTPGNLRAMVQAKLKNLRTGSNFEHRFRAADTIVKADMETHELEFMYQGGDTYHFMNSENYDQLELDDEALGDSAPWMQPGLKILAEYYNGRPIGIQLPNSLVFEIVETAPVVRGATKTASSKPAKLENGVTVNVPEFVEQGTRVRVNPSTGEYLDRAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_NEIMB
Sequence: MFSKSVTLAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVMDAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKELFGAAYANVQPHSGSQANQAVYASVLKPGDTILGMSLAHGGHLTHGASVNISGKLYNAVTYGLDENEVLDYAEVERLALEHKPKMIVAGASAYALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVPFCDFVTTTTHKTLRGPRGGVILCRDNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKEALQPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAALGKAHITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLVADVLSNPEDEANLAKVRKQVTALCNKYPVYGA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ACIAD
Sequence: MLIIPAIDLKDGKCVRLKQGRMEDDTVFSDDPVATAQHWVNEGARRLHLVDLNGAFAGTPIHKPVVEAIAKAQPELPIQIGGGIRSLETIEHYLDAGVSFVIIGTKAVQDPEFVEQACKQFAGHIIVGIDAKDGMVATDGWANVTDVKATDLAKRFADAGVSSIVYTDIARDGMMQGVNVEQTVNLAQYSGLPVIASGGVTNLDDVRLLKGKPGILGAITGRAIYEGTLSLREAQLLLDQNTL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.