PharMolix/UniProtQA huggingface dataset:
Protein: PCDA3_HUMAN
Sequence: MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-3, PCDH-alpha-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SSRP_HAEIG
Sequence: MTKKKVKPNSNTIALNKRARHDYFIEDEIEAGLELQGWEVKSIRAGKANISDSYVIFKNGEAFLFGASIQPLNVASTHIVCDPTRTRKLLLNKRELASLFGKANRDGFTIVALSLYWKSAWAKVKIGLAKGKKQQDKRDDIKEREWKVTKDRIMKNAHRRS
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: UBIG_PSEPW
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVSLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVEVEYRQITAEALAEEMPEQFDVITCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLLAIIGAEYILKMLPRGTHDFKKFIRPSELGAWSRVAGLEVKDIIGLTYNPLTKHYKLSSDVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: ATP25_UNCRE
Sequence: MNRIMLRGIQCYGCRSHVIQSFLAIADITFPAPLYHKPYTRSHLQHQSSFSSLHGQSFRGQSVAHSTSSRDPLEDNGTEQHPDSASHQSNEHVPWYLREESSEVPPHPLGSRQSIPPLPDNPPPILEGLLQHISVDIGLDDLSLLDLRSRNPPPALGANLIMIIGTARSVKHLNVAADRLCRWLRSTHKLHPTADGLLGRNELKIKLRRKARRAKLSSNAGSAFDEKDDGIITGWICVNVGSVENGKAAATEQKQDFVGFGSVADGAQIVVQMLTEEKRAELDLEGLWSGNFPPRSASEIRMFEQHFEAFAEKAVAEAANGRAAHRDPRGVRGTGSGMDHGQRRGLHTIRRVPNISVEAAVLGPAFIPRQGATVQQEPRLGPAPSVPPKASKPLNLSPETASLLHHLTQVPKDDAIRELGSGPQDLTSTLFLRLFQEALSNAEQNPDAHILAKLELIRVAVTLQHPHYSKTDLFDAFKEFAASGYDISESQALKTVKALLSFAENDPDGSHTAKRVSRSDIDLALKVLNHMSLRGMDILSREVFSMLYTASGFQVPVRPVNENPSPSSIETETSIPVSAEEFDEVRLVQDRLRKIMDAFDVKFGPDQFLTLLRFHFHHGNYDQFWAIWRKMSLLQLPRSKEFYVLLFRLHAERGNQKRAAECLSSWVPMMAREQPAVAIDADVARVIMACLLVADPDVKQRADNGDPGEYPSLWDRCWNVLVASKATQG
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: NU153_XENLA
Sequence: MAAAGGGGPGGPGTGGKIRSRRYHLSSGRTPYSKSRQQQQGIISRVTDTVKSIVPGWLQKYFNKQEEEHDRVHSASEVIVNDTEARENNAEHHIYVVDDDDDEEGNSPTDGRVTPEPIINVDEEVPSTSQSAINNTDALTRPSLHRASLNFNIFDSPALNCQPSTSSAFPIGTSGFSLIKEIKDSTSQHDDDNISTTSGFSSRASDKDLAVSKNVSVPPLWSPEVDRSQSLSHNSSMTSKKPTFNLSAFGSLSPSLGNASILNRQLGDSPFYPGKTTYQGAAAVRSSRVRATPYQAPLRRQVKAKPAAHSQQCGVTSSAARRILQSLEKMSSPLADAKRIPSNSSLSHTPEKNVMDIPENPSKRKKVESPFPPVQRLVTPKSISVSANRSLYIKPSLTPSAVSNTNSRRIQPDKHNESRKNNLQTTSQSHSFSYPKFSTPASNGLSSGTGGGKMMREKGSHYSTKPANEELDGPVLPEIPLPLSTAALPSFQFSTLSGSATSPISVTKPANSTTCRLTSSSPSFTFSSPIVKSTESNAQSPGSSVDFTFSVPAAKASSATSDESKVSAVSRAAKTHAAVSSAKNTDDEQLGFCKPAKTLKEGSVLDMLRSPGFSSSPSLLTSASSLNRSTPTLSKTVGNTFSPANVSLGVGSKQAFGLWQCSACFHENMSSDSNCISCSALKPRPTETSKKLPASPPSSNTKSTVPLSSTPGLGDIFKKPAGMWDCDTCLVQNKAEVTKCVACETPKPGTGMKATLLIPSTTKSTNPATNTLAFASCSASIPNEEMFKKPMGSWECTVCHMQNKTEDNTCVGCKAEKPGTVKSVPTAAPSGLLGLLDQFKKPTGSWDCDVCLIQNKPEANKCIACESAKPGTKAELKGTFDTVKNSVSVAPLSSGQLGLLDQFKKSAGSWDCDVCLVENKPEATKCVACETSKPGTKAELKGFGTSTFSSGTAAPTFKFGVQSSDSTAELKSGASTSGFAKSIGNFKFGLASASTTTEETGKKSFTFGSSTTNEVSAGFKFGIAGSAQTKPDTLSQSTTSGFTFGSVSNTVSLAPTATSSGSTGLQVAAVIADSNLATTATLKSAEEKKAEAPTITPFSFGKTDQNKETASTSFVFGKKDEKTDSAPTGSSFAFGLKKDGEESKQFLFGKPEPTKVDGSAASAGFAFGVTNPTEKKDIEQPGKSVFAFGAQTSITDAGASKQPFSFLTNVSSTAASSSTCGVSSSVFGSVTQSSTPATPSNVFGSAISANAPAPSSGVFGNLTPSNAPAASSTLFGNVAPSSTPSGSSGLFGTAAASSTPATSTSLFGSAAKLSAPASSGGVFNSAAPAAPASTASSVFGSVASSTNTSANSANIFGSSGGAATAPGAFVFGQPASTASTVFGNSSESKSTFVFSGQENKPVTSASTSVTPFLFGAVSASTTPAAPGFNFGRTITSNTTGTSSSPFIFGAGASGSASSSITAQANPVPAFGQSSNPSTAPAFGSSTSVPVFPAGNSQQVPAFGSSSAQPPVFGQQATQPSFGSPAAPSAGSGFPFGNNANFNFNSTNSSGGVFTFNANSGSTTQPPPPGYMFNAAAPGFNMGTNGRTTPASTISTRKIKTARRRK
What is the function of this protein?
Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope.  Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs.  May be involved in the retention of unspliced mRNAs in the nucleus.  Probably mediates tpr anchoring to the nuclear membrane at NPC.  Possible DNA-binding subunit of the nuclear pore complex (NPC) (By similarity).
What are the official names of this protein?
Nuclear pore complex protein Nup153, 153 kDa nucleoporin, Nucleoporin Nup153.
What is the protein family that this protein belongs to?
Belongs to the NUP153 family.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus, nuclear pore complex. Note=Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Colocalizes with tpr at the nuclear pore complex.
Protein: TRMD_EHRRW
Sequence: MVFNVNILTIFPEMFPGTLGYSVIGKALNKGIWNLNVIDIRSFATDKHKTVDDKPYGGGPGMIMKADVIGSAIDNVLSTNKETKLIYMSPSGVKLNQDISGQLAHFSNITILCGRFEGIDRRVLDFYDFYEISIGDYILSGGEVASMVLIETCVRLIPGVVSNVDSIRDESFTASYGLEYSQYTRPANWRGLEVPSVLVSGNHKKINLWKTQQSYRITKQRRPELTNTADGDIYE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_FRATO
Sequence: MSDYKDTLNLPKTSFSMKGNLANKEPMILNKWEKQGIYKKIREHFAGREKFVLHDGPPYANGSIHVGHAVNKILKDIIIKSKTLSGYDAPFTPTWDCHGLPIELQVEKKHGKAGQSISEDDFRKECRKYAKKQVEIQKKDFKRLGVLGDWEQPYLTMNFDYEANMIRTLAKIIENGHLSKGFKPVHWCTDCGSALAEAEVEYADKVSPAIDVKFKIKDKDKLAQAFGLDSLNHDAFAIIWTTTPWTLPANQAIAVNNQLNYSLIKIEDFYIILAENLVEQTLKRYAIENAQIIATTTGNKLTGIIAEHPFYSRHVPILHGDHVTDDSGTGLVHTAPTHGVDDFTLGKEHNLSMEIFVKGNGCYSENTKLFAGEFIFKASDRIIELLGEKKRLMNSDKIKHSYPHCWRHKTPLMFRATPQWFISMEKQGLRDKALQTIKETSWAPSWGQARIEGMVKDRPDWCISRQRTWGVPLPLFIHKETEELHPNTIEILHKVAEKIEKDGIEAWFNADDCEFITETAQYKSVKDTLDVWFDSGSSSMCILDLDKRLSYPADLYLEGSDQHRGWFQTSLLVAMSAKGSQPYKEVFTHGFVVDEHGRKMSKSLGNVTSPQDIYNTLGADILRLWTASTDYKSEMAVSDQILKRTADTYRRLRNTARFLLSNLDGFNPVTDIIEFDKLVKLDQWAIAKTKEFQDKIIEAYDKYQTHTVAQLIHHFCSIEMGSFYLDIIKDRQYTAKTDGHPRKSAQTAIYHIVHALVRWMAPILSFTADEIWDATPKTTDLPIQLCEWYTGLKSFDQDAELDLEYWAKIQEIRSEVNRVLEIKRNEDVIKASLEAEITIYADKYNYKLLEKLGNELRFLLISSKADLKVIEESTSSSIAANILGLLIEITKIEEPKCERCWHRSSTVGDNPQYKDICSRCVENITTEAGESREFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y502_PASMU
Sequence: MIYGDYNQPLQIHIDKMISVPDEKWVYGAFNLIIDGCFYPGKEINWTLNIIINWLKSFLDEDINAYDMKNCEEHSAEYLFREAVISRIGYYYDEPEEKISLEELKKIYPKKVGIEISLPEITDTGLELFFFREKEKDILVFYFQGTVSKIELDMGYIHKLIASLPDI
What are the official names of this protein?
Uncharacterized protein PM0502.
Protein: PSD_METPP
Sequence: MSERLPVLLQYLVPQRALTVFAGFVASGRWGGITTAIIRRFVRKYRVDMSEAAEPDIARYTRFNDFFTRALRPGARPLASAELVCPVDGAISQFGAIERDQIFQAKGHHYSTRALVGGDAELAARFQDGQFATLYLSPRDYHRIHMPCDGRLLRMIHVPGDLFSVNPVTARGVPGLFARNERVVCEFDGPLGPFVLVLVGATIVGSMATVWHGQVNPPRSGRLREWRYADRELRLRQGEEMGRFLLGSTVVALFPQGSVRFDPGWEPGRAVRLGEAMAFAPLL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SUMO2_XENTR
Sequence: MADDKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLNKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGSF
What is the function of this protein?
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer.  Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i, and can be promoted by an E3 ligase such as pias1-4.  This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Polymeric sumo2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (By similarity).
What are the official names of this protein?
Small ubiquitin-related modifier 2, SUMO-2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_XANP2
Sequence: MARVTVEDCIDKVDNRFELVLLAAHRARMISSGAQITVDRDNDKNPVVALREIADEHVGPEDLKEDLIHSLQKYTEVDEPEPEAVPMIASGDSSGGEDSDVMLDRMTEEELLAGLQGLVPPEHTDDDEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: GDNF_HUMAN
Sequence: MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAEDRSLGRRRAPFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
What is the function of this protein?
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
What are the official names of this protein?
Glial cell line-derived neurotrophic factor, hGDNF, Astrocyte-derived trophic factor, ATF.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family. GDNF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEH1_CAEEL
Sequence: MKTVIFLALLGLAAAEFIEIGYKVCKSDGTVSQVKADGCELTVKDGKKVCLFKKGSRPIIQIAFKPSKDTDKLKTSVRAKVGGSAMVDFPQTNSDACTYGVKCPVSAGENQIFEQSISITENHPAGEVIQVNWQLTRPDSGKEVCIIFLAEIKE
What are the official names of this protein?
Putative protein heh-1.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIA_BURCH
Sequence: MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGRPRWPLLVIFTLGTLLMRSAGCAMNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVGLSFIAFLLILPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLVANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMACYAATLGIYVWIGVTLGFGLAYWVGWAAAVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGN
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: JAR6_NICAT
Sequence: MKMLVEKIEKKFDQEKVIEEFEDLTKDAGKIQEETLKKILEQNGGTEYLQLWGLNGRTDPQTFKNCVPIVTHNDLEPYIQRIADGDLSPILTGKPIETISLSSGTTQGKPKFVPFNDELMESTMQIFKTSFAFRNREFPIGNGKALQFIYSSKQFKTKGGLAAGTATTNVYRNAQFKKTMKAMCTPCCSPDEVIFGPDFHQSLYCHLLCGLIFHDEVQVVSSTFAHSIVHAFRTFEQVWEALVVDIREGVLSSRVTVPSIRLAMSKLLKPDPELADTIYNKCSRLSNWYGLIPDLFPNTRYIYGIMTGSMEPYLKKLRHYAGELPLLSADYGSSEGWVGVNVNPKLPPELVTYAVLPNIGYFEFIPLGGNLNGIEQANSPVGLTEVKLGEEYEVVFTNFAGLYRYRLGDVVKVKGFHNGTPELQFVCRSNLLLSINIDKNTEKDLQLAVEAAAKRLVDEKLEVVDFTSHVNVSADPGHYVIFWELSGEATDEMLQDCCNCLDRSFIDAGYVSSRKVNAIGALELRIVKRGTFHKILDHFVGLGGAVSQFKTPRCVGPKNSSLLQILSSNVVETYVSTAFC
What is the function of this protein?
Catalyzes the synthesis of jasmonate-amino acid conjugates by adenylation (PubMed:17273867).  Catalyzes the conjugation of jasmonate (JA) to Ile, Leu and Val (PubMed:17273867).  Catalyzes the conjugation of JA to Ile that may mediate defense signaling and resistance to the herbivore Manduca sexta caterpillars (PubMed:17273867).
What are the official names of this protein?
Jasmonoyl--L-amino acid synthetase JAR6, Jasmonate-amino acid synthetase JAR6, Jasmonic acid-amido synthetase JAR6, Protein JASMONATE RESISTANT 6.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: CX6B1_PONAB
Sequence: MAEDMETKLKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: PYRR_BACCQ
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: YO91_BPP2
Sequence: MMAKIHEVKLHAKYFDLVLEGKKRAEFRKKDRNYERGDTLILHEWVQGVFTGRKVEARITDVTDLSDWLEDYVLLHRILGEILPLTVKLAVSSTFFINLRRRTVAIYLL
What are the official names of this protein?
Uncharacterized 12.9 kDa protein in GpA 3'region, ORF5.
Protein: RUVC_METRJ
Sequence: MTSPVRILGIDPGLRRTGWGLITAQGTKLTYGDCGVVTSDGELPLALRLRELFEGIGRIVEAVRPDEVAVEETFVNKDAQATLKLGHARAMALLVPALAGLPVFEYAPNLIKKTVAGSGHAEKVQIQAMVRFLLPKAEFRVADAADALAIAITHASHRDAHALRQAHLPGGKRRSLTGQAAAGQGLAGKGFSAAAAARIEAALAKQG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MURB_PELPD
Sequence: MNLSGLNMRGLLLADEPMSRHTSLRVGGPADLFAIPEDADDLQGLLRQLKERGIPWLAIGRGNNLLVRDSGIRGAVISLERFNRVEALGQGRIRAGAGAENLAVVRFAQEQGLGGIGFISGIPGTVGGAIRMNAGAYGTGIMERTESLTLLHDGNVREFGRDELEYGYRHLDLAAGDIILEALFRLDQREAEQTEEEIRKDLELRRAKHSVGFPSAGSFFKNPAGQTAWRLIDATGMRGERVGGAQVSQVHSNFLVNTGGATAGDFLELSRVVKKAVLASCGVTLEEEVRIVGEE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_METC4
Sequence: MTATASPSDTKGAAAPRISFVSLGCPKALVDSERILTHLRAEGYELSRRHDGADVVIVNTCGFLDSAKAESLAAIGEAMAENGRVIVTGCMGAQPEEIREKYPNLLAVTGPQAYESVVAAVHEAVPPAHDPFLDLIPPQGVKLTPRHYAYLKISEGCNNRCTFCIIPSLRGDLVSRPAGDVLREAEKLVKAGVKELLVVSQDTSAYGIDTRYATSPWQDREVRARFYDLASELGELGAWVRLHYVYPYPHVDEVIPLMAEGKILPYLDMPLQHASPSVLKRMRRPGNQEKQLDRIRRWREICPDLAIRSTFIVGFPGETDAEFEELLDWIREARLERVGCFEYEPVRGATANDLGLLVPPEVKAERKRRFMEAQSHVSLRLQRAKVGKRLSVIIDEAGPTGARGRSKADAPEIDGSVHVTSRRPVRPGDIVTVKIERADAYDLHGIAV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_HELP2
Sequence: MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKERFGSQIKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEILSGYAKDLMLLEIKDNLDALGIHFDSYASEKEVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSCTYLAGDIVYHDEKFKQNYTKYINIWGADHHGYIARVKASLEFLGHDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAVESSFEEYGLQKMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLTNAFKLLGIEIKTKISAKD
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFIF_ECOLI
Sequence: MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRADGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEWWRQNKA
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase YfiF.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: GUND_CLOC7
Sequence: MIKHLLSRGKLLLFVSVMATSSIIAGGNAYGSTAFTGVRDVPAQQIVNEMKVGWNLGNTMDAIGGETNWGNPMTTHAMINKIKEAGFNTLRLPVTWDGHMGAAPEYTIDQTWMKRVEEIANYAFDNDMYVIINLHHENEWLKPFYANEAQVKAQLTKVWTQIANNFKKYGDHLIFETMNEPRPVGASNEWTGGSYENREVVNRYNLTAVNAIRATGGNNATRYIMVPTLAASAMSTTINDLVIPNNDSKVIVSLHMYSPYFFAMDINGTSSWGSDYDKSSLDSEFDAVYNKFVKNGRAVVIGEMGSINKNNTAARVTHAEYYAKSAKARGLTPIWWDNGYSVAGKAETFGIFNRSNLTWDAPEVMKAFIKGIGGSSTTTPTTPTTPTTPTTPTTPTTPTTPTTPTTPQSAVEVTYAITNSWGSGASVNVTIKNNGTTPINGWTLKWTMPINQTITNMWSASFVASGTTLSVTNAGYNGTIAANGGTQSFGFNINYSGVLSKPTGFTVNGTECTVK
What is the function of this protein?
Has endoglucanase activity on carboxymethyl-cellulose (CMC), cellobiosidase activity on p-nitrophenyl-cellobioside (p-NPC), and partial hydrolytic activity on crystalline cellulose (Avicel).
What are the official names of this protein?
Endoglucanase D, Cellulase D, Endo-1,4-beta-glucanase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: CAPSD_CMVIX
Sequence: MDKSESASAGRNRRRRPRRGSRSASSSSDANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVAEFDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVTAISAMFADGASPVLVYQYAASGIQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDIEHQRIPTSRVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.