PharMolix/UniProtQA huggingface dataset:
Protein: ADA2B_BOVIN
Sequence: AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKFIILIVWLIAAVISLPPLIYKGDQGPQPLARPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSHCRGPRAKGGPGERESKQPHPVPGEVSDSAKLPTLASQLATPGEANGCSQPRPGEKGDGETPEAPGTPALPPSWPAIPKSGQGQKEGVCGSSPEEEAEEEEEEGCEPQALPASPASACSPPLQQPQGSRVLATLRGQVLLGRGTGTAGAQWWRRRTQLSREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPQHCKVPHGLF
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: LIVK_SALTI
Sequence: MKRKAKTIIAGIVALAVSQGAMADDIKVAIVGAMSGPVAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIQYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKQGNANIVFFDGITAGEKDFSALIARLQKENIDFVYYGGYYPEMGQMLRQARANGLKTQFMGPEGVGNASLSNIAGGAAEGMLVTMPKRYDQDPANKAIVEALKADKKDPSGPYVWITYAAVQSLATAMTRSASHAPLDLVKDLKANGADTVIGPLKWDEKGDLKGFEFGVFQWHADGSSTVAK
What is the function of this protein?
This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids.
What are the official names of this protein?
Leucine-specific-binding protein, L-BP, LS-BP.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BBE18_ARATH
Sequence: MKFQSFFSSVLIFFTTSTLLLSIPHPVSANRSNQSSFLQCLSLQLNDSNIVSKVIHTPNDTSFSSVLASSIQNQRFSAPDVPKPVLILTPVQPSDVQSAVKCARRFGIHIRTRSGGHDYEGLSYVTHKPFVILDLRNLRSITVDVDNRSVWVQTGATIGELYYEIGKKNRTLAFPAGVCPTVGVGGHFSGGGYGTLLRKHGLAADHVIDARVVDARGRILERREMGEDFFWAIRGGGGSSFCVVLSWKIGLINVPSTVTVFNVTKFSEQSALKIIHRWQFVADKVSDDLFIRVMLQRYKNMVRASFPGLYLGSVKNLLKMVNKEFPELGLEEDDCTEMSWIESVIWFAELGEEPINVLTKRTRASLAFKAKSDFVQEPMPKTAISKLWRRLQEPEAEHAQLIFTPFGGKMSEIADYETPFPHRKGNIYEIQYLNYWRGDVKEKYMRWVERVYDDMSEFVAKSPRGAYINLRDLDLGMYVGVKRSKYEEGKSWGVKYFKNNFERLVRVKTSVDPSDFFCDEQSIPPFTFVEVI
What are the official names of this protein?
Berberine bridge enzyme-like 18, AtBBE-like 18.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: LEPA_COLP3
Sequence: MKNIRNFSIIAHIDHGKSTLSDRLIQHCGGLQAREMEAQVLDSMDIERERGITIKAQSVTLDYKAKDGEIYQLNFIDTPGHVDFSYEVSRSLASCEGALLVVDAGQGVEAQTVANCYTALEMDLEVLPILNKIDLPQADPERVCEEIEHIIGIDATDAVTCSAKTGIGIEDVLETIVKNIPSPAGQIDAPLQALIVDSWFDNYQGVVSLVRVINGEVKKGDKMLVMSTGQVHQIDKVGIFTPKQTDTGVLRAGEVGFIIAGIKEIHGAPVGDTITISKKETANALPGFKKAQPQVYAGIFPISSDDYENFRDALNKLSLNDASLFFEPENSSALGFGFRIGFLGMLHMEIIQERLAREYDLDLITTAPTVNYEIASTNGDVISIDNPADLPAINNIEEIREPIVQANILVPQEYLGNVITLCIEKRGVQKDLIYHGNQVAVTYELPMAEVVMDFFDKLKSTSRGYASLDYHFIRFEAADMVRVDVMINGDRVDALAMITHRANSVARGRLLVDKLKELIHRQMFDIAIQAAIGNNVIARTTVKQLRKNVTAKCYGGDISRKKKLLQKQKDGKKRMKQVGNVEVPQEAFLAVLKLDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BIOB_CAMHC
Sequence: MDLQKIKNQILDGRNLCIEDAYELENAPLNELLEAANEVRAKFCGNYFNFCSIINVKSGKCSENCKYCAQSAHFDTKCEIYDILPFEKIMPLAKLNDDAGVARFSLVASGKGLHKKDDLQKVIEIYKKLKSHTKFHLCASFGIVSKEILAELKKSGVKTYHHNLETSRKFFPKICTTHTYDDRINTIKSALCVGLDVCSGGIFGLGESLKDRIDMAYELKNLKVSSVPINILTPIKGTPLENSAPLCVDEILRSIAIFRLILPHVFLRLAGGRNNLKNSVKTALNGGINSAITGDFLTTCGDVAQSDKNLVSECGFVYKKSFDV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y2657_BACC0
Sequence: MNKLSTKLVVAIGIGSALYGILGLWGFTIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTVTDTIAGWGIWWGWVISSGIIGFTMGFIQKRVGFSVKNGTYNKGDISYLAITGLIGIVIAIIFAGAFDIIVMGEPFDKIVIQVLGATIADVIVFLVLGLPITIGLAKSNKKHTHLKIEK
What are the official names of this protein?
UPF0397 protein BCAH820_2657.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRCA_LISMO
Sequence: MLTERQLLIFRAIIDHFTWTIQPVGSKNLLKEKGLPYSSATIRNEMGVLEEYGFIEKTHSSSGRVPSEKGYRFYVDYLLQPKKLDKSDRQMIRSFFSENYYEMEGLIQNSALMLSDLTNYTSILLGPEATKNHLSGFRFVPINNFQAMLILITDQGHVDNHLVTIPEGTTLSDIERMVNILNERLVGLSLDDLKVQIPMEVKELLGKHVRNYESFMHVFSDSFAQASQQKVYFGGKTNILNQPEFHDINKVREMLHLMEEEQDVYELFRDIPDGLQVKIGRENNNSLMEDCSIITATYNIAGERVGGIVLLGPTRMEYSRMMGLVDVMSRDLTDVLTKLYRDNQN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: NUOH_ACIAC
Sequence: MIDALYNGGLNLVAQSWWTGAVWPVLWNLLKIVAIVAPLMGAVAYLTLWERKLLGFMQVRHGPNRVGPFGLLQPLADGLKLLTKEIIQPAAASKGLFVLGPVMAIMPALAAWVAIPFGPDVALANVNAGLLLIMAITSIEVYGVIIAGWASNSKYAFLGALRASAQMVSYEIAMGFCFLVVIMVSGSMNLTQIVLSQAQGTMANAGLSFLSWNWLPLLPIFIVYLISGVAETNRHPFDVVEGEAEIVAGHMVEYSGMGFAIFFLAEYASMWLVSILGVTMFLGGWLSPVAALDFIPGWIWLGLKTFLVVSMFIWIRATFPRFRYDQIMRLGWKIFIPVTLVWLLIVGGWLLSPWNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTCB_SYNY3
Sequence: MRLEQLQAFLKVAELGSFQQAALQSEVTQSTISRQIQGLESALKCQLFHRGAQAKLTVAGELFLRRARKICQEWDVASEEISSLFQGKQTELCVAAIHSVCVSSLPSLLPKFCLGHPQIQLRVTALGSDRALKVLQDGLVDVAIIMSHRNLTNTKELAIKPLYEEQICILMASDHPLTTKKFITWENLGPYPQVIFKDGYRMRRLVEDEFSRREIPLNVSLELNIPEAFYGVVQGSEMIALMPQSLVTPVIDNPNFSVRYLFCPESGDRQDFRRQVSVVTTVDRLQIPPVAEFFNLVVDHYRCGALTVK
What is the function of this protein?
Seems to regulate utilization of fixed nitrogen by controlling the expression of a certain gene(s) involved in nitrogen metabolism.
What are the official names of this protein?
Probable nitrogen assimilation transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RNPA_DESPS
Sequence: MERYRLPKTAFVRKGWEYDAVYRGGRRLHGVGFTIIYLLNSTENNRLGISVHRKLRGAVKRNRIKRIIRECFRLHRDIFPQKADIVFAVRPGFALSSPEQIRQAVGSLCGTPCGVCNEKA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MSRA_TRIEI
Sequence: MLDTIVLGGGCFWCVESVFLSVVGVKEVESGYAGGNTKNPDYRSICSGKTGHAEVVKVSFDTEKISLSQILEIFFATHDPTTPNRQGNDVGTQYRSVVMCHSQEQKDIAQEVISTLGNNGTFENPIVTEVVDLKDYYRAEEYHQNYFNKNPYQPYCVFSIPPKLQKLKKYFPDQVSA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CMOA_HAEIG
Sequence: MVKDTLFSTPIAKLGDFIFDENVAEVFPDMIQRSVPGYSNIITAIGMLAERFVTADSNVYDLGCSRGAATLSARRNIHQPNVKIIGIDNSQPMVERCRQHIAAYHSEIPVEILCNDIRHVEIKNASMVILNFTLQFLPPEDRVALLTKIYEGLNPNGVLVLSEKFRFEDTKIDHLLIDLHHQFKRANGYSELEVSQKRTALENVMRTDSIKTHKVRLKNVGFSQVELWFQCFNFGSMIAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CU76_LOCMI
Sequence: GYLGGYAAPALAYGAAAVAPAAITSQQSNILRSYGNLGQVSTYSKTVDTPYSSVSKADIRVTNNAVYAAPAAYAAAPVAYAAPALGYARTALAAPALGYARAAYAAPAVAAGGLLGVAYSAAPAVAHLTYSGLHAAYAY
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 76, LM-ACP 76, LM-76.
Protein: QUEC_METJA
Sequence: MKAITVLSGGLDSTVVTLIAKDLGYEVTAITFNYGQRAAKREINSAKKICEILGIEHIVVDLPFVKQFGKSSLITEKEIPTLKMEELDSEKAYETMKAVWVPARNVIMFGIASGFAEALDAEKIFIGINKEEGVTFPDNTIEFVEAFNKVLEYGTLNKVKIEAPLYDKTKEEIVKLGAELEKKLGVEVLKYSYSCYHDNGEDFLHCGKCESCMRRKRAFLMAGVEDKTKYIE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RNY_LACLS
Sequence: MDIISIVLLVLLVVLVVAFIFCAQNIKKNKQDAESLFNEAENKANEVMASAKREAESLKREAEAFKKEARYTLREEEQKQRREIEDEFKQERQELKETEKRLKQREEILDRKDDTLTKKEENLDSKEENLVRKTDTLSKREEQLAHIEEKKRLELERISNLSMDDAREIILSETRDGLTKEMAQTIRQSEEKAQAEADKRAKNIISLAIQRVSSDSVAEQTVSVVNLPDDGMKGRIIGREGRNIRTFEALTGIDVIIDDTPEAVVLSGFDPIRREIARMTLEQLVQDGRIHPARIEELVEKNRKALDHKMREYGEQAAFEVGAHNLHPDLMKIMGRLHFRTSYGQNVLDHSVEVAHIAGNLAGEMGENEALAKRAGFLHDIGKALDHEVEGSHVEIGTELARKYKENPIVINTIASHHGDTEPLSNIAVLVAAADALSAARPGARRESIENYIKRLKDLEAISTSFDGVETAFALQAGREIRVMVKPDKLTDDQIVILARDVKNRIEDEMDYPGNIKVTVIRETRAIDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CYB_CHAAI
Sequence: MANLRKTHPLLKIANDALVDLPTPTSISAWWNFGSLLGLCLVAQIITGLFLAMHYTADITTAFSSVAHICRDVNYGWLIRNLHANGASFFFICVYLHIGRGLYYGSYLYKETWNIGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGNMLVEWIWGGFSVDNATLTRFFAFHFLFPFLIAAFTIIHLLFLHETGSTNPVGLNSDADKIPFHPYFSYKDLLGFAILLIALISLSLFAPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILMLVPILHTSKQRSLTFRPFTQLLFWLLVADVIILTWIGGLPVEHPYVVIGQIASFLYFFLFLFLIPLSGWLENKALKWSCIDSSASERRSCKPDVGG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CSPLF_POPTR
Sequence: MASPQNTSQKRFFQANSPGGMPTASQSQRSRILAQITLRFLAIAFTVTAIPVMITAKEPVSLLGLAITPSYKQSSAMKFLLGVNATVFAFTALSMLFVWPLRRSGSKPINYFFLHLHDMVMTLLLISGCAAATAVGYLSQYGQPETYWSPICDIVKKFCHQMLISTVLSYLAFFCYLALNILSVHKLMSRATE
What are the official names of this protein?
CASP-like protein 1F3, PtCASPL1F3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NPT2C_RAT
Sequence: MPNSLAGDQVPNPTLDAIGLVDWSLRNAGTSGSTPGLEEGGTDPWTFSQLKNTDQLKEVGTASKLHQVVSGFLKACGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVVVTVLVQSSSTSSSIVVSMVASKSLTVQASVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFGGSAVHGIFNWLTVLVLLPLENATAALERLSELALGAASLQPGGQAPDILKALTRPFTHLIIQLDSSVVTSSITSNTTNSSLIKHWCGFRGETPQGSSEECDLSGSCTERNSSASPGEDRLLCHHLFAGSELTDLAVGFILLAGSLLVLCVCLVLIVKLLNSVLRGRIAQAVKTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFLGSNIGTTTTALLAALASPADTLLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVAIVYLLLTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNVLQRHRPSWLPRRLQSWAWLPLWLHSLEPWDRLVTGCCPFKAYSNSHMTSKVAHCYENPQVIASQQL
What is the function of this protein?
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:11880379).  The cotransport has a Na(+):Pi stoichiometry of 2:1 and is electroneutral (By similarity).
What are the official names of this protein?
Sodium-dependent phosphate transport protein 2C, Sodium-phosphate transport protein 2C, Na(+)-dependent phosphate cotransporter 2C, Sodium/phosphate cotransporter 2C, Na(+)/Pi cotransporter 2C, NaPi-2c, Solute carrier family 34 member 3.
What is the protein family that this protein belongs to?
Belongs to the SLC34A transporter family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membrane in the kidney.
Protein: SACA6_HUMAN
Sequence: MALLALASAVPSALLALAVFRVPAWACLLCFTTYSERLRICQMFVGMRSPKLEECEEAFTAAFQGLSDTEINYDERSHLHDTFTQMTHALQELAAAQGSFEVAFPDAAEKMKKVITQLKEAQACIPPCGLQEFARRFLCSGCYSRVCDLPLDCPVQDVTVTRGDQAMFSCIVNFQLPKEEITYSWKFAGGGLRTQDLSYFRDMPRAEGYLARIRPAQLTHRGTFSCVIKQDQRPLARLYFFLNVTGPPPRAETELQASFREVLRWAPRDAELIEPWRPSLGELLARPEALTPSNLFLLAVLGALASASATVLAWMFFRWYCSGN
What is the function of this protein?
Sperm protein required for fusion of sperm with the egg membrane during fertilization.
What are the official names of this protein?
Sperm acrosome membrane-associated protein 6, BACHELOR-like protein.
What is the protein family that this protein belongs to?
Belongs to the SPACA6 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein.
Protein: NADD_CHRVO
Sequence: MNARVGVFGGTFDPVHHAHLRMARAFADELALDEVRLIPAGQPYHRLEGPHASAAQRLDMVKLAIAADARLAVDEREIRRARPAYTVDTLRELRAELGDAAELWFLIGGDSLAALSSWKDWRKLFRLANLAVAMRPGFDPAALPPEVFQEWQARQVSDFSNRTASGTIRPLALPPLDLSATRLRARLAADEPVDGLIDPAVLAYIRRQRLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: AHL16_ARATH
Sequence: MAGGTALTPTSVGSKSVPMRNHEATERGNTNNNLRALPKAVQPVSSIEGEMAKRPRGRPAGSKNKPKPPIIVTHDSPNSLRANAVEISSGCDICETLSDFARRKQRGLCILSANGCVTNVTLRQPASSGAIVTLHGRYEILSLLGSILPPPAPLGITGLTIYLAGPQGQVVGGGVVGGLIASGPVVLMAASFMNAVFDRLPMDDDEAASMQNQQYYQNGRSRPLDDIHGLPQNLLTNGNSASDIYSWGPAQRVMSKP
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (PubMed:25336567).  Encodes a nuclear matrix protein that acts in the maintenance of genomic integrity by silencing TEs and repeat-containing genes through epigenetic machinery.  Acts as a chromatin remodeling factor that modifies the architecture of FLC and FWA chromatin by modulating both H3 acetylation and methylation leading to the regulation of FLC and FWA expression (PubMed:23394836, PubMed:23836195).  Negatively regulates floral repressors including MAF4 and MAF5 (PubMed:23733063).  Plays a transcription activation role in anther development.  Regulates the expression of arabinogalactan proteins (AGPs) involved in the formation of the nexine layer of the pollen wall (PubMed:25336567, PubMed:24804694).  Binds AGP6, AGP11, AGP23 and AGP40 promoters (PubMed:25336567).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 16, Protein TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK, Protein TEK.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM1_CANGA
Sequence: MIRLFQLYEHQLKVRPKLTNSIMTGALFGIGDVSAQLLFPSGPDTLPPSAQTNDVKRGKYDIPRTVRAVVYGSMIFSFIGDRWYRFLTKVKFSNKPAKHWSNMVLRVCVDQLGFAPLGLPFYFGCMSLLEGHGLGAAREKIKLQWWDTLKTNWCVWPLFQMVNFSLVPLQHRLLAANVVAIFWNTFLSYTNSQIPVGGHKLTVQYPPTVQ
What is the function of this protein?
May be involved in cellular response to stress.  Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
What are the official names of this protein?
Protein SYM1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UBIG_PARPJ
Sequence: MTNADPHELQKFSDLAHRWWDPNAEFKPLHELNPIRLKWIDAHAHLAGKTVLDIGCGGGILSESMAGLGAHVKGIDLSTQALGVADLHSLESGVTVDYEEIAAEALAAREPAKYDVVTCMEMLEHVPQPAAIVEACKTLVKPGGWVFFSTLNRNVKSYLFAVIGAEYIARMLPKGTHDYARFIRPSELASFVRAADLRTADIKGIVYNPLSKHFMLSADTSVNYMLACRRDV
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: HCFC2_MOUSE
Sequence: MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTVTNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPQPPPSGFPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPATKGVVPSPRESHTAIIYCKKDSASPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENPETSPHDCEWRCTSSFSYLNLDTAEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKATTNSFHVKWDEVPTVEGYLLQLNTDLTYQATSSDSSAAPSVLGGRMDPHRQGSNSTLHNSVSDTVNSTKTEHTAVRGTSLRSKPDSRAVDSSAALHSPLAPNTSNNSSWVTDMLRKNEVDEICALPATKISRVEVHAAATPFSKETPSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSKVGNADVPDYSLLKKQDLVPGTVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISKNVDGIHLSWEPPTSPSGNILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQDQEKDVGPWF
What are the official names of this protein?
Host cell factor 2, HCF-2, C2 factor.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYSP_THEPA
Sequence: MYSSSVVSNPNERLVNNRVENDLESSDDTLSTQAKPVSRLLTRKLLLGVVVLFFLAGVSVVSYFLFSKYKMLNKFKRELDDHLTKDFPNLERSKRDTCFDELTRLFGDGFLSDDPKLEYEVYREFEEFNSKYNRRHATQQERLNRLVTFRSNYLEVKEQKGDEPYVKGINRFSDLTEREFYKLFPVMKPPKATYSNGYYLLSHMANKTYLKNLKKALNTDEDVDLAKLTGENLDWRRSSSVTSVKDQSNCGGCWAFSTVGSVEGYYMSHFDKSYELSVQELLDCDSFSNGCQGGLLESAYEYVRKYGLVSAKDLPFVDKARRCSVPKAKKVSVPSYHVFKGKEVMTRSLTSSPCSVYLSVSPELAKYKSGVFTGECGKSLNHAVVLVGEGYDEVTKKRYWVVQNSWGTDWGENGYMRLERTNMGTDKCGVLDTSMSAFEL
What are the official names of this protein?
Cysteine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: DNLJ_LEPIN
Sequence: MPKKKEDSQKTLSEKEAKGLIAKLSDEIRHHQYLYYVKNDPKISDFDFDQLFRRLQDLEEEFPQFKDLASPTLVVGSDLDKDFEKFQHKLPVLSLINTYNDNELLEWVNKTDPEGLYSVEWKIDGASIVLYYENGILKNGVTRGSGGIGDDVTDNIRTIRNIPLRLPKPITVYLRGEVFMTFKDFEEFNALSSGKYANPRNLSAGSIKQKNSSDTAKRPLRIFTYDATFPNMEKKFKTHQEIFSKLEKLTFPVPPNTAFVSGSKIAKTIQEFKKQKDSLGFPTDGLVIKLNDISKRDALGYTSHSPRWARAYKFDAIMKESKIVDITYAVGRTGKITPRAEIEPISLAGTTVTFATLHNQDYIDELGVGIGAIVRVAKRGEIIPAVEEVVTPGKEVFKIPDRCPSCNTQTIKKESLVDLFCPNPDCPDRVKNGIIFYCQRKQMDIEGLGDKQIEFLYDHDYIKSIADLYDLKDQKEKLMEEEGFGEKSVNIILKGIEQSKQKDFRFLLPSLGLSELGHKVTELLIEHGIDSIDEILSIAKDQKKIESLLEIPGIGPSTIQAFQENFSDKRILKLIERLKKAGLKMKADPIQVADQQPFAGQSWCVTGSFENFQPRDKAMDLIVYYGGRKVSAVSSKTTHLLAGPGAGSKLEKANELGVSVYDEKQFLDLLKSLKIDFKNLI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NUOB_RICCN
Sequence: MKNNFYQEDELLSNELSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARQTH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.