PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_BACMK
Sequence: MRSDMIKKGFDKAPHRSLLKATGLKDEDFDKPFIAICNSFIEIIPGHKHLNEFGKLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAALRINIPTVFVSGGPMAAGKTSKGEVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILAIDPRREELIKQAAEKLKILIERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLALAQEAGLDYDMNRIDAVSRRVPHLCKVSPASNWHMEDIDRAGGISAILKEMSRKEGVLHLDRITATGQTLRENIAHAEIQDKEVIHSLENPHSEEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPGMPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGTIALLEQGDIVCIDVEERLLEVRVSDEELEKRKKGWKRPEPKVKTGWLGRYAQMVTSANTGAVLKIPNFD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MTP_DROME
Sequence: MENKNKKCLRTLLLLALFLGLLEDGKTALIAPNSQQIFKLQNQVILQELGRDSSSAETSYTFETDLKINSVWSGDEDQLLEVFISGSKVDASGKARSITRIPDRPFYISLVRGQPDKVIAHTSKDQSLLNLERGIASLLQLRLDASQEEELDVSGLCRVSYNVKSSTKVEKTKRDCSLWDLRVNYNPEEALGVTQQAQETVFYELSSEGTLLHAESQENHRLNLAAKPDVGSFVKSSLILQHVSQGSEEVKQLQLGSLDKAIQSLLEWYRVFELESDVDGMISAIKEQTLEDQLKASLTELQSADVGKSSLALAYVKLIPLARITRQEQFEDLLTEHAEVLPQLVDLLGAVQTFDAHNATFGFLYKESETTSEQLDLLEKYLQSLAVATHPDRKIVEHLFGLLEQESIKKHLKLRESVIQTVATLTRQSGLDVEDPLLKEVRSYLLQGLTSKEPTLYIRALQNLQDPATIEALLEHAQTGEAPNLSVAALQALKAFPLGSFNSSHRLQFESIFYQRKRRFDSSARTLALDIILSLRPTQEQLGNFLDYLASNDRQFEIKTYVLQKLRMLAEKCPRFRALFKSELVKRRHVNNYNVLGQKGLTTVLTRQLSQAPAFNETLLSTQEVYQGILKRGSVEFLLHAGRSQASSFKLGIYTAGLGSLVGDGDSGDGNDAIPADDEFSEDEAVTAGMEISVQGAQLRPLVFFSGQTELMGHVWGGSASDSTPAYQATTLSQDNEHYIILTSGATLHWRVLGARSVDLNGKVGFSLWNRNAQTEIQQNTGSAVLGHLAVGFTYAKLVQDFSITHEPKLSLNADLDFYSGIKLCMQLQRPEQLLKQTNVRSVFLQSVDRPYAKHVRSTLSHKTAGCTFALNQKNNEMCNLIFRDL
What is the function of this protein?
Catalyzes the transport of phospholipids such as phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine) and phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine) between membranes.  Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B.
What are the official names of this protein?
Microsomal triacylglycerol transfer protein, MTP.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: COAD_BURCM
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFKGLLKDFVRTNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMGGPAA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NOCSJ
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSGRRYAGIGDVIVATVKDAIPGGNVKKGDVVKAVVVRTVKERRRPDGSYIRFDENAAVILKNDGEPRGTRIFGPVGRELREKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NUBP1_RAT
Sequence: MEGAPHGCPGADSAQAGRGASCQGCPNQKLCASGAGAAPDPAVEEIREKMKTVRHRILVLSGKGGVGKSTFSAHLAHGLAEDGDTQVALLDIDICGPSIPKIMGLEGEQVHQSGSGWSPVYVEDNLGVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGDVDYLVIDTPPGTSDEHLSVVQYLAAAHIDGAVILTTPQEVALQDVRKEISFCHKVKLPIIGVVENMSGFICPKCKRESQIFPPTTGGAEAMCQALKIPLLGKVPLDPHIGKSCDKGQSFFVEAPDSPATAAYKSIIQRIREFCNSRQSHDENLISP
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Implicated in the regulation of centrosome duplication.  Negatively regulates cilium formation and structure.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP1, Nucleotide-binding protein 1, NBP 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis. Localized at centrioles and in the nucleus at interphase. Colocalizes with nubp-2 at prometaphase. Specifically localizes to the axenome of motile cilia as opposed to primary non- motile cilia. Localization is independent of NUBP2 and KIFC1.
Protein: SYL_SHEPC
Sequence: MQEQYNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYENIEYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQVQDGCCWRCDTPVEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGHDKTFDIYTTRPDTLMGVTYVAIAAGHPLAEIAAQTNPELAAFIDECKNSTTSEAELATMEKRGVATGLFAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDFEFAKKYGLAIEAVIKPVDGDVDISEAAYTEKGILFNSGEFDGLDFEAGFNAIANKLVAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVIPTPADQLPVLLPEDVVMDGIQSPIKADKEWAKTQVNGQDALRETDTFDTFMESSWYYARYCSPQADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYINEKGARVWVSPLDVATTEKDDKGRITKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASEYIAQDNSEALDVSKLTSEQKALRREVHKTIAKVTDDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALSAVMRLLYPIIPHVSFTLWNDLGNTGSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADKDSVEALGMNDEHVIKYLDGLTVRKVIYVPGKLLSIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_SCHJA
Sequence: MSGGYPALELSAEDLRLMLAAHVHVGETNMNFQMSTYVHGRTKDNFHIIKLDKTWEKILLSARAIAAIDTASDVFAIGSRPFSQRAVLKFANYTGATAMAGRFTPGAFTNQKQSCFREPRLLVVSDPLSDHQAVMEASSVNVPLIALCNTDSPLTRVDIVIPCNNKSTHSIAVVWWFLAREVRRIRGEDTRLQQWSVLPDLFLYRDPNEEEQNVEDPEDARLEPVIPGADAEAAETWGVEPSMPVGSLGDMGIAAPGYGPVGGTAGGWSNLDADPTETW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KORA_ARCFU
Sequence: MEMELIQGNEAAVRGAINAGCNFFAGYPITPSSEIAHGMAELLPKFGGVFIQMEDEIASISAVIGASMAGAVAMTATSGPGFSLMQEGMGYAAITESPVVIFNVMRAGPSTGIPTAPSQGDAMQARYGSHGDYPIVVLAPASVKDMYYLTVEAFKIAFRFSTPVIVLSDEIVGHMRESVALPPLGEIESYEKRAKNLIDGRRRHRTGLVHTENGLPTTDLEEYEKLLRLLFAKFDDFRPMVRFEGEEGVLFVAYGSSYRLAKSSAKLLAEKGVSAGILKLESLFPFPEDAVRRYSKKADLVVVPEMNAGQVVKEVERVCCCRVKGVSYFGSLILPEKLVEIVEGEL
What are the official names of this protein?
2-oxoglutarate synthase subunit KorA, 2-ketoglutarate oxidoreductase alpha chain, KOR, 2-oxoglutarate-ferredoxin oxidoreductase subunit alpha.
Protein: DNAG_HALH5
Sequence: MNQRIPQETIEEIRRSVDILDVIGEYVQLKKQGRNYIGLCPFHGENTPSFSVSPDKQLYHCFGCGAGGNAFTFLEQIEGFTFVEAVETLAKRANVVLPERVSPSVKQNRDEELLISIQEFAAKFFHHVLMLTEEGKAGRTYLERRGFTKEQIEHFQIGFAPPHWDALTNVLAKRDVDLKKAGESGLLVERESDGKRYDRFRNRVIFPIRNGKGKIVAFGGRTLGDDKPKYLNSPESPIFQKGKLLYGFYQARPAIRKENEAVLFEGYVDVIAAWKAGVTNGVATLGTSLTEEQARMIRRNAETVIICNDGDAAGAEATFRSADLLQQEGCHVKVAMIPDGLDPDDYIQKYGAERFKKDVIGESLTLMKFKMKYFRMGRNLQNEGERILYIEEIIKEIAKLSKAVERDHYLRQLAEEFSLSLDALKQEQYRIYREMKRQNQVSQGKTNTVRQKKHDFEQKRLLPAYQNAERILLAHMMRNVSVAETVQERLGGRFNVDHYQAIVAHLFAYYAEGFEPDPCTFIQRLEDQELIRVATELAMLEINEEINDQELNDYIEKIEMYPKWLELQQIESALKKETDPVLYATRKQELINMKKQLKL
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: SUS1_LODEL
Sequence: MTRDGDNSELNQIKSKIQEHLVSSGNYELISKQLKLQLIESGWYDKVAQIAMDELNNSSSKDTKDGGRAYTTKSLSDLYTVVKPKAEGLVPNEVRENMLKRIELYLDDLIE
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: RL4_LEGPC
Sequence: MEITTIDTKSKLKLNKEIFAYTYNEGLVHQAVVTFMNNARSGNSAQKTRSEVSGGGKKPWNQKGTGRARAGTIRSPLWRSGGVTFASKKRDYSQKLNKKMYKRALRSIISELCRTGNLVVVSDFQCDNHKTKDFLKKMNQMEISNALIIMSEVGENEYLGSRNLIDYDICDVTTIDPVSLLRFEKVVVTEAAIKKIEEQLQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NRDR_XANCP
Sequence: MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVSEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MAIP1_MOUSE
Sequence: MALAARLLPLPLLSRPLPGPVTRLRTLGSTEVRLTLTEICCLCRRRLGSSAAPIPRYTRAWTSPALRSWSSRRSLLGRVEHPPALASLPASPSRSYSTEEQPQQRQRTRMIILGFSNPINWVRTRIYAFLIWAYFDKEFSIAEFSEGAKQAFAYVSKLLSQCKFDLLEELVAKEVLQILKEKVTSLSDNHKNALAADIDDIVYTSTGDISIYYDEKGRKFVNILMCFWYLTSANIPSESLSGANVFQVKLGDQSVETKQLLSASYEFQREFTQGVKPDWTIARIEHSKLLE
What is the function of this protein?
Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation.  Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB).
What are the official names of this protein?
m-AAA protease-interacting protein 1, mitochondrial, Matrix AAA peptidase-interacting protein 1.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LPXD_PSYA2
Sequence: MITIEQLISQIEQRQPVLNKAELNAEQRRLSLKGIGNLMMANRQQLSFLANPHYLSSLANTHAGAVLITAEHHNEAPNDTVALIVASPYLAYASVSQLFARQPSVSGIHPTAVIADSAVIGNQVTIGAFCVIGEQVQIGDRSALQAHVVVEDNTAIGTDCVIKPQVVIGHDCIIGNHVRLHAGVSIGSEGFGFAPTRNPSVTGWERIAQLGRVLIGNHVRIGSQTCIDRGAIDDTVIGNHVIIDNLVQVAHNVRIGDGTAIAAHTGIAGSTSIGKRCIIGGAVGITGHIDITDDVTLSGMTMVTKSITTAGSYSSGTAAMPTTNWRRAAVRFRQLGRD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYGA_STRPM
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFEKFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPRC1_MOUSE
Sequence: MAARRGRRDRVAPPPTGGPGPDPGGGVRGGSWASRSQAPYGTGGSVSAAEQVHEEGNDSSFVSLSRLGPSLREKDLEMEELILQDETLLETMQSYMDASLISLIEDFGESRLSLEDQNEMSLLTALTEILDNADSENLSPFDTIPDSELLVSPRESSSLHKLLNLSRTPPERDLITPIDPLGPSTGSSRVSGVEVPLADSPWDFSPPPFLETSSPKLPSWRPSRPRPRWGQSPPPQQRSDGEEEEEVAGFSGQMLAGKLDNSVNNVLDFPMHLACPEEEGTAEGADAPASAPGDESISSLSELVRAMHPYCLPNLTHLASLEGELEGQADADADELTLPEGCVVLEIVGQAATTGDDLEIPVVVRQIPSGSQSVLLDESLGSSPALQLLMPTMESETEAAVPEVAPCPDEELPLSSACLLEPREIMESLTPKEPQSLPASASQGSQKVPRKGRKKKNKEQPTACVEACTRRLRSSSRGQSTVSAEVNSQAGSSQKQPQEELQREAAALQSRGKPRAWARAWAAALEKTGSENLERSAGQDSPAEEDALDLCPKLLETSQANPTLSLNDSAQADSMPVDSVEGDSPAVGNAAPGDQASSGTELVGSLPVGPNLTSPVLADKKGIEPAVAIPTSDNLSPADVLANTVAADPVPNDPAPADPVLVKCRPTDPRRAAAAAAAAAQGSRPSLQSADHPKVVSPEGKDVVGPLKVEGSTSATTQEAKPRPLSLSEYRQRRQQRQTEAEDRNSQPPVVGKWPSLPETPTELADIPCLVPSAPARKTAPQRSPIAVPETVSVGSNPVSPTPEPSASKLMVSTHSEQVSSHEMPLAVRPPPPPLPSVSPAGPIPSTVPAPLPPFPPSVPPLLPLPSGGHGVPRLPPPPLQPPGLPVSMRQMPPDPYTQYAPVPPWSCYPSVSPPGYSCLPPPPTMPIVSGTPGTYAVPPTCNVPWVPPPAPVSPYSSSCAYGSLGWGPGLQQPPFWSTVSPPPLSSVPTGRAVPPTPVEPSGDPAGPPEDVLPGPVTPSLSSGPASPAAPPVEPTKPEAQPVPVSPQPKHKVSTLVQSPQIKAPPTLSTEGVVFEESVSERLKSETQENRPKEKPISTAIKSVPVPKQSAVAKLPAVHPARLRKLSFLPTPRAQGPEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPLPASADSLAVGNSGIDIPQEKKPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGITEAKPPATACLQEGAHSPSPVHVGSGDHDYCVRSRTPPKRMPALVISEVGSRWNVKRHQDITIKPVLSLGSAAPPLPCTATSQEPLDHRTSVEQADPSAPCFAPSTLLSPEASPCRSEMNARTPPEPSDKQQSMRCYRKACRSVSPSSRGWQGRRGRSSRSVSSGSSRTSEASSSSSVSSSSRSRSRSRSRSFSPPNKRWRRSSCSSSGRSRRCSSSSSSSSSSSSCSSRSRSPSVSPCRRSDRRRRYSSYRANDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELKQRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRRQFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR
What is the function of this protein?
Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth.  Involved in the transcription coactivation of CREB and NRF1 target genes (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1, PGC-1-related coactivator, PRC.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with NRF1.
Protein: LSPA_STRMU
Sequence: MRKIVLAVTALLLVALDQLSKFFVVKYIRLGTIVEFIPNLVSLTYLRNTGAAFSILENQQWLFTVITFIVLGVAFYYLIKQMQTQNFWLLASLLLIISGGLGNFIDRLRLGYVVDMIHLDFVDFAIFNVADSYLSVGVALLIIALWKEEKNGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG8_DEBHA
Sequence: MRSQFKDEHPFEKRKAEATRITQRFNDRLPVICEKAENSDIQEIDKRKYLVPGDLSVGQFVYVIRKRIKLPSEKAIFIFINDILPPTAALMSTIYEEHKDEDGFLYVLYSGENTFGETEMKRLNVADLELDFDSVN
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: NU1C_CYAP4
Sequence: MNPGIDLQGSFIELLTNVGLPPGVAKAVWMPLPMLLMLVGATIGVLISVWLERKISAAAQQRIGPEYIGPLGVLAPVADGLKLLFKEDIVPANADAALFTLGPILVVIPVFLSYLIVPFGQNLLISDLGIGVFLWISLSSIAPIGLLMAGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAIAMMSNSLSTVDIVNQQSGLGILGWNVWRQPVGLILFWIAALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYVNLVLSALMVAILYLGGWDFPIPLNLVASWVGVSETNALFQVIAGAVGITMVLLKAYFFIFLAILLRWTVPRVRIDQLLDLGWKFLLPVGLVNLLLTAGLKLTFPIAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: AOX_PICST
Sequence: MLSVQTTRAAKLQLGQLPSIAYTARSGRLHHQFYSTVAEKTANPTPNTSDKTNIFDIRTKVYDETDIRKHDDNQFITHPLFPHPTFSQEDCLKVGYEHRPPRTFGDKMAFRGIELVRGSFDFVTGYKKPKTQADIDSGFKGTRYEMTEGKWLTRCIFLESIAGVPGAVASFIRHLHSLRLLKRDKAWIETLLDEAFNERMHLLTFIKIGKPSWFTRTIIYVGQGVFCNLFFLFYLANPKYCHRFVGYLEEEAVSTYTHFVHELQSGKLPKFENIKIPTIAWQYWPELTENSSMLDLILRIRADEAKHREVNHTLANLDQRKDRNPFGLAIPDLKEPQPESGLKVTKPHGWEKEELKL
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial, SHAM-sensitive terminal oxidase.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: MCR1_MAGO7
Sequence: MFARPAIRACQSLKQPVRRYTNTPPPQSGNANNSRVGILIASAVGMAGFGTYFMFGQGTTPAAGVKALGAEPKKALEMEKGFVSLQLDDVEVVNHNTKRLRFKLPEDDMVSGLHVASALLTKFKPEGAEKPVLRPYTPISDEDQKGYLDLIVKKYEGGPMSTHIHELVPGQKLDFKGPLPKYEWSANKHPHVAMIAGGTGITPMYQIMRAIFKNPADKTKVTLVVGNITEEDILLKKQLAELENTYPQRFRAFYVLDNPPKDWAGTKGYITKDLLKTVLPEPKEENIKVFVCGPPGMMKAISGNKVSPKDQGEVSGILKELGYKQDQIYKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RL16_OPITP
Sequence: MALAPARTKYRKSQKGSRAGNAKRGNTLAFGEFGLQSLTRGPMTGQQIEAARVTISRHLKRKGKLWIRVFPHKPITKKPAEVRQGQGKGPVEFYIAQIRPGAVLFELAGVPATTAKEAFRLADAKLPFHCRFIAREGAVV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PMI28_ORYSJ
Sequence: MASSMAPAAAMAILLLALLMPATLCSRSGPPSSKHGHGGHAKRAPPPASPVVPVAPQAAALVRATCNSTAYYDVCVSALAADPSSTTADVRGLSAIAVSVAAANASGAAQAAAALANGTAPLAAAAAGDGTVQALLRACAGKYGDARDALAAAKESMGQQDYDLATVHVSAGAEYPQVCKALFRRQRPGAYPAELAAREEALNKLCSVALDIIALLTSSPASNNNNS
What is the function of this protein?
Pectin methylesterase (PME) inhibitor that inhibits PME in vitro.  Functions as a critical structural modulator by regulating the degree of pectin methylesterification and the physiochemical properties of the cell wall components.
What are the official names of this protein?
Pectinesterase inhibitor 28, Pectin methylesterase inhibitor 28, OsPMEI28.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CHB2_BOMMO
Sequence: MAAKLILFVCATALVAQSVLSIGCGCGGRGYGGLGYGGLGYGGLGGGCGRGFSGGGLPVATASAAPTGLGIASENRYEGTVGVCGNLPFLGTADVAGEFPTAGIGEIDYGCGNGAVGITREGGFGYGAGYGDGYGLGFGGYGGGYGLGNGGYGGCGCGWGY
What is the function of this protein?
This protein is one of many from the eggshell of the silk moth.
What are the official names of this protein?
Chorion class B protein L12.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: PCKA_RHOP5
Sequence: MTETGVRNGAYGADKFGLKNLAGVTWNPGAPQLYEYALRAGEGVLSADGALCVDTGIFTGRSPKDKYTVRDANTESTVWWGGNQSITAEQFETLYQDFLKHAEGMQLFAQDLYGGADPSFQIKTRVFTEMAWHSLFIRTLLRRPETAALASFVPELTIIDLASFRADPKRHGCQSENVVAIDFTRKIVLIGGTQYAGEMKKSVFTTLNYYLPDKGVLPMHCSANVGPDGDTAIFFGLSGTGKTTLSADPNRTLIGDDEHGWGKDGVFNFEGGCYAKCIKLSAEAEPEIFAASNRFGAILENTVLDPITRKPDFNDGSKTENTRSAYPLESIPNASLTGRAGLPKNVVMLAADAFGVMPPIAKLTPAQAMYHFLSGYTAKVAGTERGVTEPSPVFSTCFGSPFLPRDPSVYGNMLRELIAKHGVDCWLVNTGWTGGIYGTGSRMPIKVTRALLTAALNGSLRNVEFRTDPYFGFAVPTALPGVPSDILDPVKTWADKAAFDVTARKLVGMFQKNFSKFEAMVDAEVRAAQPEAKLAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.