PharMolix/UniProtQA huggingface dataset:
Protein: KIT_HUMAN
Sequence: MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.  In response to KITLG/SCF binding, KIT can activate several signaling pathways.  Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.  Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase.  Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1.  Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.  KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor.  Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.  Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.
What are the official names of this protein?
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Note=Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head.
Protein: ILVC_ACAM1
Sequence: MARLYYDADANLDLLANKTVAIIGYGSQGHAHALNLKDSGVQVIVGLYEGSKSAAKAQEAGLTVKSAADAAKAADLIMILLPDEVQRTVYTQDIQPHLSADKVLAFAHGFNIHFAQVVPPSDVDVVMVAPKGPGHLVRRTYTQGQGVPCLFAVYQDASGQARDRAMAYAKGIGGTRAGILETTFREETETDLFGEQAVLCGGLTALIKAGFETLVEAGYQPELAYFECMHEVKLIVDLIVEGGLAKMRDSISNTAEYGDYTRGPRIVDDRTKAEMRRVLHEIQTGQFAKEFVLENMSGKAGFTATRRRESEHAIEEVGKDLRAMFSWTDKA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PYRC_BACC2
Sequence: MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIEVNGNLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICSMPNTRPVPDCREHMEDLQKRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: RS15_BUCAI
Sequence: MSLSAIDTKKIILKYGKSEQNSGITEVQVVLLTNQINYLQIHFSQHKKDHCSRRGLLNMVSKRRKLLDYLKKKNISRYSALIEDLHLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PURL_BACC2
Sequence: MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVERILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEKVAEVPADALAEEAPIYHKPSKEAAYFAEFQAMKMETPKVENYKEALFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEMGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMIHGKIFGQSPSIDLDVELKRQKQVLEAIQAGLVQSAHDVAEGGLAVAISESAIGAKGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTSTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS2B_ARATH
Sequence: MASSMFSSTAVVTSPAQATMVAPFTGLKSSASFPVTRKANNDITSITSNGGRVSCMKVWPPIGKKKFETLSYLPDLSDVELAKEVDYLLRNKWIPCVEFELEHGFVYREHGNTPGYYDGRYWTMWKLPLFGCTDSAQVLKEVEECKKEYPGAFIRIIGFDNTRQVQCISFIAYKPPSFTEA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit 2B, chloroplastic, RuBisCO small subunit 2B.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FMT_DEIRA
Sequence: MSAAAGPKVAFFASPAFALPVLEALRAEFEVVLVVAQPDKPVGRGLKLTPPPVAARAAELGLPLAQPHKLRGNADFAAQLRDSGADVAVTCAYGKILPAGVLEIPRFGFLNTHTSLLPRYRGAAPIQWALIRGETVTGTTIMQTDEGMDTGPVLLQEELPIRPEWTSVELSAALSEQAAALIVRALRTLETLTPQPQDEAQATHAPLLVKEDGFVRWADPAQAVLDRFRGVAAWPQTTAFFGGKRLKLAGLTLGQGKGQPGKVLQVGAGGLTVACGEGAVCIATVQPEAKKAQPAQVWAQGQNVEQGARFDLWEPPQG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MNMG_ECO81
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP12_BPLSK
Sequence: MAKQLSTARKFKMITGKDLFQQQKAMDTELKKEDGEITDLMEFVQYGLYLALFQDNIVKAKSDFSDFRSSFEFDTDGKGLKELVELWQKEI
What is the function of this protein?
Probable chaperone for the tape measure protein.  Might help to maintain the tape measure protein in solution during tail assembly.
What are the official names of this protein?
Chaperone protein gp12, Gene product 12, gp12, Probable chaperone protein gp12.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus chaperone protein gp12 family.
Protein: DEOC_DESPS
Sequence: MNTIISPKEIALYIDHTLLKPEASPAAIRTLCAEAREYSFKTVCVNSCYVPLCVEELQACPVDVCSVVGFPLGAMLSSAKAYEAKLAVAAGADEIDMVINIGLLKAGELEAVRADIETVFAACGEADLKVIIETGLLSDAEKKSVCQICKEVGVAFVKTSTGFGHGGATVADVELMRAVVGERCKVKASGGVRNLADARALIAAGANRIGASAGIAIVNGEEVPPSR
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA2_COREF
Sequence: MAGFDWFWKALGGKQGRNQKRSLAIVDQAEAHTRDLEALDDAHLAARARTLVGDGTPQDPAELLAVLGIAAHRTLGMRPFPVQSQAVLRLIEGDVVHMATGEGKTLVGAMAATGLGLQGKTVHSITINDYLAVRDAEWMRPLVEFFGLSVGAISETMTPEQRREAYRCDVVYGSVSEIGFDVLRDQLITRRADAVQRRADVAIIDEADSVLVDEALVPLVLAGNQPGHAPRGKITEVVRRLKENDHYTVSEDRRNVFLTDKGAAALEQALGITSLYDDEHVGTTLVQVNLALHAQALLIRDIHYIVRDGKVQLIDASRGRVADLQRWPDGLQAAVEAKEGLAVTEGGRILDTITLQALVGRYPMVCGMTGTAVEATDQLRTFYNLHVSVIERNNPLRRFDEADRIYATMAEKNRAIIEEIAHLHHTGQPVLVGTHDVAESEELADALRDLDIEVSVLNAKNDAEEARIIAEAGDIGRVTVSTQMAGRGTDVRLGGPDESHYDQVVELGGLAVIGTARHRTARLDNQLRGRAGRQGDPGLSLFFVSLEDDVVVTGGAGESVTAQPDATGLIDSNRVRDWVAHCQRVTEGQLLEIHSQTWKYNKLLADQRVIIDERRARLLDTDLAWRELSERAQDRAAGLEGVDREVLEQAARDIMLYHLDLNWSEHLALMDDVRESIHLRAIARETPLDEYHRIAVREFKTLAQQAVDDAVETFRTVVIDDRGAHLEDAGLARPSATWTYMVSDNPLAGSGNSVISGIGNIFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: LIPA_MYCLE
Sequence: MTVAPEDCRLLRLEVRNAQTPIERKPPWIKTRARMGPEYTALKNLVRRVALHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQTMGLRYTTVTGVARDDLPDGGAWLYATTVRAIKELNPSTGVELLIPDFNGQPARLAEVFDSRPQVLAHNVETVPRIFKRIRPAFTYQRSLDVLTAAREAGLVTKSNLILGLGETADEVRTALADLRKTGCDIVTITQYLRPSMRHHPVERWVRPEEFVEYTQYAEGLGFSGVLGGPLVRSSYRAGRLYEQAAGTRTVGTSVSR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1948_CLOBM
Sequence: MSGDKTIQFDPVENKKTLTKEILTKVYNSLLEKGYNPVNQLVGYLISGDPTYITNYNGARSLVIKLERDEILEEVIKSYLGIN
What are the official names of this protein?
UPF0297 protein CLK_1948.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: MURQ_FRAP2
Sequence: MSMLKNINTEKRNPRSFNLDSMSVQESVNLMIDEEYGVIEALKEQSLNIAKIVEVTSQALKKGGRIVYVGAGTSGRLGILDAVECPPTFSVDYNTIIGLIAGGEKAFIQAQEGAEDNPDFGKEDLLKINLTAKDVVIGIAASGRTPYVIGALEYANSIEATTIAISCTKQAKISSYADYNIEAVPGPEVLTGSTRLKAGTTQKLILNIISTLSMVSVGKVYQNLMVDVKPTNEKLVERSKNIICEATGVDYVTAQDFYMKANKSVKVAIVMILNDCDYEQALAILKKNNNFIKS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MURG_BURO1
Sequence: MTASQRTLMVMAGGTGGHVFPGLAVAHRMEAAGWRVVWLGNPAGMEATLVPKHGIPMEYVRFGGLRGKGLKTKLTLPVNLLRACWQSLGALRRVRPDVVLGMGGYITFPAGVMTALSGRPLVLHEQNSIAGLTNKVLAKLAKRVLVAFPGALPHAEWTGNPIRAELAHTEPPHARYASRSGPLNVLVVGGSLGAAALNEVVPRALALLAPGERPRVVHQAGVKHIEALKANYEAAGFAAGEDVRLVPFIDDMAAAYAAADLVICRSGAMTVSEIAAVGVAALFVPFPYAVDDHQTTNAAFLAEAGAAVLVQQRDLSAELLADWLRGQSRASLADMAERSRALAKPEATDEVARVCAKAAGANLETLQ
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
Protein: RECO_XYLFM
Sequence: MLIEHEVAFVLHVRPWRETSLLVEVLTQAYGRLGLIARGVQGLKKQTLRAALQPLQWIRFSAIQRGELGQLRQAEALDTAPRLKGETMLASFYINELLLRLVPRHAPVNELYLAYSQTRERLRTNDSLAWSLRLFERDILETLGVGFNLECDANGTPLDPAAHYVLDPLEGPRRLLSEHNNAERRDTATGHVLLALAHKQIPNTNDLAGLRRSMRAVLLHHLGGRGLKSWEMIAAFRHQDTSP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TSAD_STRA1
Sequence: MKDRYILAVESSCDETSVAILKNDKELLANIIASQVESHKRFGGVVPEVASRHHVEVVTTCFEDALQEAGIVASDLDAVAVTYGPGLVGALLVGMAAAKAFAWANKLPLIPVNHMAGHLMAARDVKELQYPLLALLVSGGHTELVYVSEPGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMIKEDHLEFSFSGLKSAFINLHHNAEQKGEALVLEDLCASFQAAVLDILLAKTQKALLKHPVKTLVVAGGVAANQGLRERLATDISPDIDVVIPPLRLCGDNAGMIALAAAIEFEKENFASLKLNAKPSLAFESL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_ALKEH
Sequence: MAIVAVYPGTFDPLTNGHADLVQRSCRLFDRLIVAVAAYPSPSKRPAFTLDERLALAREVLKDMPGVEVEAFDTLLVDFVRARGATVILRGLRAVSDFEHEFQLASMNRQLIEEVETVFLTPAEQHAYISSSLVREVAALGGDVTRFVPPVVARALARRYSGPNRDGDGDGQGG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YD179_YEAST
Sequence: MPTILYNTNSSLITKYRRPNASNQYKGFLSKKGHTRLNSKSSGDIWEKDCSHTKNSGNDVSFESEFEKDSVEYLRDLCFSIYPNSLHQKIRSIEALPDLQVNTFIALIFQNFVKSWYGIKIPTDDSKFLTELYNLVQDLITYLKSSKINYHALLLDYIPCLLSSHLKALNDSSQNNDLVYEQYCKLTLYDSKRYPMLFTEIIQSKMSTKSLLQRSFLDSFLNELVFGHIFNSIAEPYYLLEGLNKICIRIKLNSAGNTRNEVTHGKPKCDPWLFVSNVKHKILQMTRLLAYSTSTEAANMNTAEIQETAFLQRYIFTFFTDDFFKLSMRKPFLFSICRTLQHWISKLNALNRVMYRTFDNIVQTKITSPVTIGNLFSLLRHSLFPNDNMMGPPRVLPVGDAFLEFREECISNLWDVCMTYKLDHILAIKRSDIADLIICISKNRDCNKLLIYRIIDCVIAQLP
What are the official names of this protein?
Uncharacterized protein YDR179W-A.
Protein: RS14Z_STAAC
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: TDRD9_RAT
Sequence: MLRKLTVDQINDWFTIGKTVTNVELLGLPPAFPAEAPREEVQRSEEVPSEAPTAQAQDPVKATALARPASAFGRSLSQRSSEVEYINKYRQLEAQELDIYGQDQPPSGPGLRSPLAKISNVACIPETTYKYPDLPINRCKEEVISLIESNSVVIIHGATGSGKSTQLPQYVLDHYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVGLEKTATEDTRLIYMTTGVLLQKIVSAKSLMEFTHVFIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVILMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHTIEQYYLNDLGHIYHSGLPPYRLEEPVITKDVYEVAVSLIQMFDDLDMKESGNKTWSGAQFVSERSSVLVFLPGLGEINYMHELLTNMIHKRLQVYPLHSSVTLEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGRVSKGYCYRLIHRDFWDSAIPDHVVPEMLRCPLGSTVLKVKLLDMGEPRALLATALSPPSLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLIVLGHVFGCLDECLIIAAALSLKNFFTMPFRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGELRHPKDELDWGRLNYIQIKRIREVAELYEELKNRISQFNMFVDPRHPVLDQEYPYKQRFILQVVLAGAFYPNYFTFGQPDEEMAVRELAGRDPKTTVVLKHIPPYGFLYYKQLQSLFRQCGQVKSIVFDGAKAFVEFSRNPTERFKTLPAVNLAVKMSQLKVSLELSIHAAEEIEGKVQGGSVSKLRNTRVNVDFQKQTVDPMQVSFNTLDRPRTVADLLLTVDVTEVVEVGHFWGYRIDERNAELLRQLTAEINRLELVPLPIHPHPDLVCLAPFTDYNKESYFRAQILYVSGNSAEVFFVDYGNRSHVDLDLLREIPCQLLELPFQALEFKICKMRPSAKSLICGEHWSGGANGRFAALVSGCPLLVKVFSIVHSVLHVDVYRYSGAQDAVNIRDVLIREGYAELAEESYESKQSYEVLKGFFAKSVDTMPDGSVSSPMKDDEKHLIQILLESFASNRLGAPNCKAVLHGPFNPYELKCHSLTRISKFRCVWIEKESINSVVISDSPADLHQRMLVAASLSVNETGSTMLLRETSLMPHIPGLPALLSMLFAPVMELRVDREGKCYTGVLCGLGWNSTTEAPILPEHDIELAFDVCFNVEDIVEINILRAAINKLACDGPHGPKYLGPERIAQLQENARQKLLGLFCRLKPREKITPQWHEKPYEWNQVDPRLVIEQAEREGGPGKSTCLYQLHTPVVLSP
What is the function of this protein?
ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4.
What are the official names of this protein?
ATP-dependent RNA helicase TDRD9, Tudor domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP- bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies.
Protein: HIP2_RHOTE
Sequence: GTNAAMRKAFNYQDTAKNGKKCSGCAQFVPGASPTAAGGCKVIPGDNQIAPGGYCDAFIVKK
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein, HiPIP.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
Protein: SYY2_PHOLL
Sequence: MKENIDKLLSNIAIMEPPLGLQDKLALARQENRKLTIKLGFDPTAPDLHLGHAVVLQKLKDFQDEGHRIVVIIGDFTAGIGDPTGRNKLRPPLTPEQINKNSQTYINQLAKVINIENIEIRKNSEWFNNMPFSNVIKLISKITLAQIMHRDDFKTRFESKAPVHLHEIIYPILQGYDSVMIDADIELGGTDQLFNNLVGRTLQEAYEKKGQIVITMPLLEGLDGIEKMSKSKNNYIGLTDNANDMYGKVMSIPDSVIINYLTLATDMEAEKQSAIVSQLELGLNPMKIKKDIAYNIVKRYHDDISAKEATEHFERVVQKRTPEEADHDVLILPKGSYITLLDLCSVALPAISRSELRRLIRSGAVRVDKSKEDDEIKNIEVIPGTLIWIGKRYKFRIGS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 2, Tyrosyl-tRNA synthetase 2, TyrRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.