PharMolix/UniProtQA huggingface dataset:
Protein: CITD_ACTSZ
Sequence: MQITKTAVAGTLESSDAQVRVAPASTLEIELNSSVGKQFGDDIIATLKDVLNQLDVTAAQIVVEDKGALDCVLRARLKAALLRATDEPINWEKML
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BACCQ
Sequence: MAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDADYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFRTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SURE_CAMJ8
Sequence: MKEILITNDDGYESEGLKKLIKMLTKEFKAKITIVAPASEKSACSHSITLTKPLRFVKVGKRFYKLDDGTPADCVYLALHALYKKRLPDLVISGINKGANVGEDITYSGTCAGAMEAVLQGIPAIALSQFYKKSEKELDYKNALQITKKIIQNIFDKGFPLEKKEFLNINFPAKSKIKGIKICKAGKRVYNFEAHSNVNPRGVEYYWLAAANLDFEDEKNSDIALLKKGYATITPIMLDLTAYEKMKKVKKWLKANDE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL3_MOUSE
Sequence: MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEETGQELTELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP) (PubMed:18376416).  Required for normal cytokinesis and cilia signaling.  Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E.  Targets NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium (By similarity).  Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms (PubMed:15979089).  Required for PKD1:PKD2 complex targeting from the trans-Golgi network to the cilium (PubMed:25405894).
What are the official names of this protein?
ADP-ribosylation factor-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium. Note=Detected predominantly in the photoreceptor connecting cilium. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules (By similarity). Present on the mitotic spindle.
Protein: MALK_VIBVY
Sequence: MASVTLKNVCKAYGDVLISKNVDLEINEGEFVVFVGPSGCGKSTLLRCIAGLEDITSGDLYIGEERMNDVEPSKRGVGMVFQSYALYPHLNLYDNMSFGLKLAKADKKEIDKRVEQAAEILQLGHLLERLPKALSGGQRQRVAIGRTLVSQPKVFLLDEPLSNLDAALRVQMRAQITKLQRQLGCTMIYVTHDQVEAMTMADKIVVLDGGFVSQVGKPLELYHYPENRFVAGFIGSPKMNFMSVQIVDVESERVQVKLSNGVTFWVPVDGTTVNKGDRMSLGVRPEHLVSSAQGDAVIDGEVMIVEKLGNETQVYLNLESADADVIYRQPDTLDVDSGDRLEIGIPAHRCHLFHSDGRACKRLFNEKGVER
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Maltose/maltodextrin import ATP-binding protein MalK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL24_CAMJR
Sequence: MAVKLKIKKGDSVKVITGDDKGKTGKVLAVYPKTLKVVVEGCKIAKKAIKPSEKNPNGGFINKEMPMDISNVAKVQE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MURB_SACEN
Sequence: MSGAEGTRDGASPTGGSALAAYTTLRLGGPAAGFVVAEDAETLADAVREADAAGSRLLVLGGGSNLVVADEGFDGHVVRIATRGLRFDSVGDGLVQLTAEAGEDWDAVVAETVRQGLGGLECLSGIPGLTGATPVQNVGAYGVEVSELLLSVDLLDRRTGNVRTVRAEDLGLVYRGSVLKHSDQAVVLRVRFLLRDGGRSAPVRYAELARTLDAEPGSRVDVAEAREAVLALRRGKGMVLDPADHDTWSAGSFFTNPIVEAADLSAVLSRIGAKVGPDQRVPQYPASDGRTKLSAAWLIERAGFGKGHPGPGGRARLSTKHTLALTNRGEATTADLLSLAREVRDGVLAQFGVSLAPEPVLVDCAL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_FRATM
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAAITKVMAEKNGGMARKFDEIDSAPEEKARGITINTSHVEYESPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPKIVVFLNKCDMVDDEELLELVEMEVRELLDQYEFPGDDTPVIMGSALRAIEGDEAYVEKIVELVQAMDDYIPAPERDTEKPFILPIEDVFSISGRGTVVTGRIERGVVNVGDEVEVVGIRPTQKTTVTGVEMFRKLLDRGEAGDNVGILVRGLKRDDVERGQVLCKPGSIKPHTKFEAEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDITGAVELPEGVEMVMPGDNVKMTITLINPIAMDEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_MYCPA
Sequence: MGLEEQLPGGILLSTVEKVAGYVRKNSLWPATFGLACCAIEMMATAGPRFDIARFGMERFSATPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPKWVLAMGVCASSGGMFNNYAIVQGVDHVVPVDIYLPGCPPRPEMLLYAILKLHEKIQQMPLGVNRETAIAEAEQAALSARPTIEMRGLLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPE_NEIG1
Sequence: MSIMQVEVVSGEQKIYSGEATFIVVPTVQGELGIYPRHEPIMSLVRPGALRLTVPGEDKEVLVAVSGGILEVQPDKVTVLADVAVRSAEMDRARAEEAKKAAEAGISQAKDDKALAEAHKALAAAIAQLKTLDYIRSHKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MATC_NEUCR
Sequence: MNLLNMQPKRSEQPAMFEENRASSQEGQDLEVMYKKLHQLQARLSRSVLSEAIKEFEENLRCLFHEAKLLLCSTRTKYRQSWFGSSNEFGSSDERRIIKTSCCIIESTNTILNFLSFLEKNRGLPFGGDQRLQQAAYKGQQFAFRLLRSLTLHKAAQEVPGKDFGLVYGKDVYVLNGHILHRSKQEIVGQAGGRNWHVDHTLHPLRRVPGTPWHKFFGNLEVGDDKQLRLFDDDAAVDSYRVGPQKFFVVIPETAEFILDEVSSEHQRVATIHTENGHVQPPAPTSIQQEALLRKLDFAMTTSLPGYVVEGQPEIVFHHEGLRQIPVDYSQERPLSILSHVFTRPALWGEGLELADHFDPRDGVQQEEHIYYI
What is the function of this protein?
Required, together with mating-type protein A-3, for efficient ascospore formation.
What are the official names of this protein?
Mating-type protein A-2, Mt A-2.
What is the protein family that this protein belongs to?
To P.anserina SMR1.
Protein: IOLC_BACAA
Sequence: MNPLIFKENRPFDLIAVGRLCVDLNANETQRPMEETRTFTKYVGGSPANIAIGAARLGLQTGFIGKVSDDQMGRFITGYLKDNKINTDQIPIDCTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEKSNDQVTAERWFSHHAKIVVIKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLMQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAEISAFMETAEELV
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: FADB_SALPA
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGQALEVLEKQHDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTLAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRLPRMLGADSALEIIAAGKDVGAEHALKIGLVDGVVKQEKLIEGAIAVLRQAITGDLDWRAKRQPKLEPLKLSKIEAAMSFTIAKGMVAQTAGKHYPAPMTAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDIETPKQAAVLGAGIMGGGIAYQSAWKGVPVIMKDINDKSLNLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPETVLASNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVIAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKEYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVDDLLASVSQPKRDFSDDEIIARMMIPMINEVVRCLEEGIIASPAEADMALVYGLGFPPFHGGAFRWLDTQGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPIIPRLNQPVRLVL
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: 3AT_PERFR
Sequence: VIETCRVGPPPDSVAEQSVPLTFFDMTWLHFHPMLQLLFYEFPCSKQHFSESIVPKLKQSLSKTLIHFFPLSCNLIYPSSPEKMPEFRYLSGDSVSFTIAESSDDFDDLVGNRPESPVRLYNFVPKLPPIVEESDRKLFQVFAVQVTLFPGRGVGIGIATHHTVSDAPSFLAFITAWSSMSKHIENEDEDEEFKSLPVFDRSVIKYPTKFDSIYWRNALKFPLQSRHPSLPTDRIRTTFVFTQSKIKKLKGWIQSRVPSLVHLSSFVAIAAYMWAGITKSFTADEDQDNEDAFFLIPVDLRPRLDPPVPENYFGNCLSYALPRMRRRELVGEKGVFLAAEVIAAEIKKRINDKRILETVEKWSPEIRKALQKSYFSVAGSSKLDLYGADFGWGKARKQEILSIDGEKYAMTLCKARDFEGGLEVCLSLPKDKMDAFAAYFSLGING
What is the function of this protein?
Catalyzes the transfer of the p-coumaric and caffeic acids from their CoA esters to the 3-glucosyl moiety of a range of anthocyanidin 3-O-glucosides, 3,5-di-O-glucosides and cyanidin 3-rutinoside.  Anthocyanins are ubiquitous colored pigments that are responsible for petal color.  Does not act on delphinidin 3,3',7-tri-O-glucoside.  Recombinant enzyme can use caffeoyl-CoA but not malonyl-CoA as alternative acyl donor.
What are the official names of this protein?
Anthocyanidin 3-O-glucoside 6''-O-acyltransferase, 3AT.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: MED13_MOUSE
Sequence: MSSSFVSNGASLEDCHCNLFCLADLTGIKWKRYVWQGPTSAPILFPVTEEDPILSSFSRCLKADVLGVWRRDQRPGRRELWIFWWGKDPNFADLIHHDLSEEEDGVWENGLSYECRTLLFKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKSEHLSCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHVTLAQQSNSPFQVILSPFGLNGTLTGQAFKMSDSATKKLIGEWKQFYPISCGLKEMSEEKQDDMDWEDDSLAAVEVLVAGVRMIYPACFVLVPQSDIPAPSSVGASHCSASCLGIHQVPASTRDPAMSSVTLTPPTSPEEVQTVDPQSAQKWVKFSSVSDGFSTDSTSHHGGKIPRKLANHVVDRVWQECNMNRLQNKRKYSATSSGLCEEETADKIGCWDFVEATQRTSCSCLRHKSLKTRNTGQQGQAPSLGQQQQVLPKHKTNEKQDKSEKPQKRPLTPFHHRVSVSDEIGMDTDSASQRLVISAADSQVRFSNIRTNDVAKTPQMHGTELANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQHFYQMPTPDPLVPTKPMEDRIDSLSQSFPPPFQEAVEPTVYVGTAVSLEEDEANVAWKYYKVPKKKDVEFLPPQLPNDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDEIVQQYQIKNQYLSAIASDTEQEPKIDPYAFVEGDEEFIFTDKKDRQNSEREAGKKHKVEDGTSAVTVLSHEEDAMSLFSPSKQDAPRPTNHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGSKKSASGSDDKASSKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKEYGSVDTAPGGTVLEGNSSSVGTQFRIEVEEGFCSPKPSEIKDFSYVYKPENCQVLVGCSMFAPLKTLPSHCLPPIKLPEECVYRQSWTVGKLDLLPSGPSMPFIKEGDGSNLDQDYGPAYTPQTHASFGMPPSSAPPSNGGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASAQGSVKYENSDLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDCNFDSCCICVCNMNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDELDIIGRNTDCGKEAEKRFEALRASSVENVNGGLKESEKVPDELILLLQDQCTNLFSPFGAADQDPFPKVGISSNWVRVEERDCCSDCCLALEHGRQFMDNMSGGKVDEALVRSSCLHPWAKQNDASVQCSQDILRMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGYDYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCRLGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDLGPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGVPISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLDTGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHPLDSNQTSDVLRFVLEQYNALSWLTCDPAVQDRRSCLPVHFVVLNQLYNFIMNML
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 13, Thyroid hormone receptor-associated protein 1, Thyroid hormone receptor-associated protein complex 240 kDa component, Trap240.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIM_SYNAS
Sequence: MQITPENTWAAVKAIRSRAPLIHNITNYVVMNSTANALLALGASPVMAHAQEEVEEMVGIAQALVVNIGTLSPSWVRAMASAALKAADRGIPIILDPVGAGATAYRTRTAFQLLETVSPTIIRGNASEILAFESVETMETRGVDSTELSQNAVDAGRRLNDSYGSTVCISGETDFIIGDRAILGIRNGHPLMTRVTGLGCTASALCGAFAAVNSSFTLAAAQAMAVMGIAGEMAAEISPGPGSLQLHFLDILYRLTEEDIARRLRIVAGE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RL11_FERNB
Sequence: MAKKVVAQVRLVLEAGKATPAPPVGPALGQRGVNLMEFCKKFNAVTADKAGLLIPVIVTVYDDRSFTFITKTPPASFLLKRAAKINSGSSEPKRKVAGKVTRQQIKEIAELKMQDLNANDLEAAMKIIEGTARSMGLEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: COAX_CHRVO
Sequence: MKLLIDAGNSRVKWALYQGEDCVRQGAAEHGELAGLAAVWRDLPLTGAWMSSVARREVADALAAAVPCPLHRVHAERRFGDVRNHYRNTAEQGADRWLAVLAARELCRGDVIVACAGTALTVEALTAEGDYLGGLILPGHGLMLQSLAQGTANLNRPAGEVVDFPQGTQDALASGAIAALAGAIAEQRRRLAERTGRAPATVILTGGDAARIAPWLAAPMQIVDNLVLMGLLKVANT
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_THEFY
Sequence: MTQSTASAHKTPVVTRTAEEIQALRPQLGRLALVPTMGALHTGHRSLIAQAREHAESVAVSIFVNPLQFGPNEDYDRYPRTFDHDLRVCAEEGVDVVFAPTVDVMYPDADGDSLGQIVTVDPGSMGRVLEGEFRPGFFHGVLTVVNKLFNLIRPDVAVFGQKDAQQLAVVRRMVRDLCLPVTIVAAPTVRDPDGLATSSRNVYLSAEERASALALSKALFAGADAASSGPAAVLAAARAILSEAARATPPVSVDYLALVDPTTFTEVGDDYRGDAVLAVAAWVGETRLIDNVPLTL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_MYCTU
Sequence: MRKHPQTATKHLFVSGGVASSLGKGLTASSLGQLLTARGLHVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLPGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITDEIKRRILAMAQPDADGNRPDVVITEIGGTVGDIESQPFLEAARQVRHYLGREDVFFLHVSLVPYLAPSGELKTKPTQHSVAALRSIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVISTPDAPSIYDIPKVLHREELDAFVVRRLNLPFRDVDWTEWDDLLRRVHEPHETVRIALVGKYVELSDAYLSVAEALRAGGFKHRAKVEICWVASDGCETTSGAAAALGDVHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARSVGLTNANSAEFDPDTPDPVIATMPDQEEIVAGEADLGGTMRLGSYPAVLEPDSVVAQAYQTTQVSERHRHRYEVNNAYRDKIAESGLRFSGTSPDGHLVEFVEYPPDRHPFVVGTQAHPELKSRPTRPHPLFVAFVGAAIDYKAGELLPVEIPEIPEHTPNGSSHRDGVGQPLPEPASRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Is essential for M. tuberculosis growth in vitro and ex vivo (PubMed:26097035).  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (By similarity).
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YR298_MIMIV
Sequence: MEKVKKSNKYSSKTSRSRNKSGSKTSQKKTSRSTSKSTSKSTSKSSNKSNKSNKSVKKSVPKINKSSKLNLSSSGSDNVESDSFARKRNITVFTDGSCLGQWTSWCFWRHRYSFSKRRITRY
What are the official names of this protein?
Uncharacterized protein R298.
Protein: NS1_I54A2
Sequence: MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSEVRRNKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: ARGB_PROM9
Sequence: MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMENDNLKKAFFRDIALLSSVGVCPIVIHGGGPEINNWLKKLEISPKFENGLRITDQKTMDIVEMVLMGRVNKQIVKGVNKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTMEGISHNINADFVAGEIAAAINAEKLILLTDTQGILKEKDNKNSLVEKMNLKEARNFIDKKIVTEGMIPKTECCIRALAQGVKAAHIIDGRIEHSLLLEIFTNSGIGTMIVA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1411_DROME
Sequence: MASSKELCSIREWAPLTEVIERIPARLQRGFFPANLNLTCVDATEEFLAMGSDAGIVFWYNRHTGEMQKLKAEVATRITCVRVVNSVEYMVAAGCANGQVSIFQIQKELPRDLDLVAPCTKSRPIERYTIRDLHKCVVSCCEWSKNGMKLYSGDRQGVVVLTELDYQAHLSKSVEILSEAYEIVQLSVRQSYLLVATLYRCIVCQMDAQTSQWNITQVGKKDRKQLIDCGAIFLKKQEANKPQLVCGRPGLRFWVADAAGNVSKTVIFRDAVLRSPTWEIPILNPKQRSEPSGTHHTSASTSSTRHSGLADGDVGYVASSNFRQLYLYDGHDSLLVTHDDATLYVLNLDRLKVEAVARGLRKILDFCVCGKEIFVLEGNRTLLRLAPLPEPPNKTAKVIFNPLMPPPVPVLGSHLSQLESPIELQAEPVLQNAEECFELSPVEQLNLNVPIEIAVESPLTQQNRRLEIFRRIGEMDFEQSIVHTTRKTSVGKPPEASGVGIVEIGHETHELRLPLTNAATLMEASYCQMENNGLASPLDMKAAFLQHLPDALSPTTLQKTVAEKAKTLAAELDLPEVHLAPLSQEELHAVQAQTPQISDPLIRCYPTHLEEASIQTSSRENATNPADDYHVGEPVDGIRSFGVSKRKMAPLKFVLSQPKPTLKLEENRDDEEYTSFLPDFRRAGDPLAIHKETPATSDSNTSSEWEFLDN
What are the official names of this protein?
WD repeat-containing protein CG11141.
What is the protein family that this protein belongs to?
Belongs to the WD repeat KIAA0329 family.
Protein: RS16_STRGC
Sequence: MAVKIRLTRMGSKKKPYYRINVADSRSPRDGRFIETVGTYNPLVAENQVTLKEDRVLAWLENGAQPSDTVRNILSKEGVLKKFHDSKYSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: UFC1_DROYA
Sequence: MVDDSTRKTLSNIPLLQIRAGPREKDVWVQRLKEEYQALIKYVENNKQSGSDWFRLESNKEGTKWFGKCWYMHNLLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGIAHAMALGLAPWLAVEIPDLIEKGIITYKEK
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: GCS22_PAEAT
Sequence: MQIDFAPSRQSTLGVEWELALVNARTGELVSVANDVLKGVAANHPDLNEDDEHPHIKRELLLNTVELVTGICETVKDAKEDLSRSLAAVREVTDPMGVEVFCAGSHPFSPPLLQPVTDKERYAKLIERTQWWGRQMVIYGVHVHVGIDHRDKVLPILDGLVNYFPHFQALSASSPYWAGEETGYASQRALMFQQLPTAGLPFQFETWEAYESYVQDMFTTGVIDATSEIRWDIRPVANLGTIEMRICDGLATLEEVGAIAALTQCLVDEFSSILDAGGSIPTMPPWHVQENKWRAARYGMEAIIILDAEGNEQLVTEHLAETVSRLEPVAAKLGCSEELADVLKIIQRGASYQRQRRVAAEHNGDLQAVVMDLVQQMRKGPDA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.