PharMolix/UniProtQA huggingface dataset:
Protein: SMG8_DROYA
Sequence: MMKDYYTWTYPDIPENVSQELRQLKSSLVVVGIVGRSKCDQANKMQAFGMEPPIEHKAKEGQVQCYYKLGTSSLLLHFETTYDEAILGQMIDVCMEDVETPFDFDSFYERMRCRFVRMMLLALHACHIVVYVETGQTFDPTLVTVFQLLKFAREQHLMQFLPQMLRETPSARMSERARLCAPRILFLFENFPRDEPKTRECVSAYEFQTEDCIYELLRHHNIVTNSSSSSLVALPNNKQFVFFNAHEQLHEDKLLKAIDCLNQAMYKPDAKEEEEDLEILELAPFEGFVKPYNLPVDDKELEKQQYKQDHTVWHFLQRHVQDALLGCFDEGSFKQHSQQGQFQLLNIHEWHNYMATLHKLLVENAKDPNQETSNEDYKLFLKSFDESLNYEKKFWAHLCELGLKKGIAAYKNAAPANYGNSTHRQLLADATVAFEEEGRGPQAKAALAKMAAICQKHWQDGRQQCEQLSLRSHPCTLPKNLPHEKHNSGVIHISSCNCGRTQGRREDPFNLRQANYEFYEHIAQMCNLCVKVKQYQLPIFEPSVSDYRAAAFEAAFPLLHTGKSGAPQDEDGEEDAEDEEGQEQQQPAEEQRQNTASNGCSQPLSPTFGSDLNMSIAGFGASLNESQASSEQLSNSEQNSTSSGTSSADTENELVVELQELHAKKEARDDAGPADAFSTSTTEYLPGLVHTVSNFGLLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVQLRLVHAPKQQHHTHHQQQHLGKKQQRWKKQGDRLSLKIFVGMEYECSRGHRFMMCAPDRVLRGGADIERETCSKVVHNNMPLYYPCPCRSQTSYLAQLMRIHVVTPKAPVNIIVDPKVCVGKGKYTFTLGSIVPPRLSQSAYWIIRLPYVYQGDDVLIAPPEKLEPDDPLAGGYLLPGMFGVAETDPTLDLNEPGRMGASAAGNFTRI
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: PELET_DROME
Sequence: MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAPAKGQTFKRRRLNADAVPSKVIEPEPEKIKEGYTSGSTQTESCSLFNENKSLREKIRTLEYEMRRLEQQLRESQQLEESLRKIFTDTQIRILKNGGQRATFNSDDISTAICLHTAGPRAYNHLYKKGFPLPSRTTLYRWLSDVDIKRGCLDVVIDLMDSDGVDDADKLCVLAFDEMKVAAAFEYDSSADIVYEPSDYVQLAIVRGLKKSWKQPVFFDFNTRMDPDTLNNILRKLHRKGYLVVAIVSDLGTGNQKLWTELGISESKTWFSHPADDHLKIFVFSDTPHLIKLVRNHYVDSGLTINGKKLTKKTIQEALHLCNKSDLSILFKINENHINVRSLAKQKVKLATQLFSNTTASSIRRCYSLGYDIENATETADFFKLMNDWFDIFNSKLSTSNCIECSQPYGKQLDIQNDILNRMSEIMRTGILDKPKRLPFQKGIIVNNASLDGLYKYLQENFSMQYILTSRLNQDIVEHFFGSMRSRGGQFDHPTPLQFKYRLRKYIIGMTNLKECVNKNVIPDNSESWLNLDFSSKENENKSKDDEPVDDEPVDEMLSNIDFTEMDELTEDAMEYIAGYVIKKLRISDKVKENLTFTYVDEVSHGGLIKPSEKFQEKLKELECIFLHYTNNNNFEITNNVKEKLILAARNVDVDKQVKSFYFKIRIYFRIKYFNKKIEIKNQKQKLIGNSKLLKIKL
What is the function of this protein?
P-element transposase that specifically mediates transposition of P-elements.  Mediates both; precise and imprecise excision.
What are the official names of this protein?
Transposable element P transposase, P-element transposase, THAP domain-containing protein, DmTHAP.
Protein: PSBN_LACFR
Sequence: METATLVAISISGSLVSFTGYALYTAFGQPAQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TCF23_HUMAN
Sequence: MSQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGYSDLDSTTASTPSQRTRDAEVGSQVPGEADALLSTTPLSPALGDK
What is the function of this protein?
Inhibits E-box-mediated binding and transactivation of bHLH factors.  Inhibitory effect is similar to that of ID proteins.  Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers.  Lacks DNA binding activity.  Seems to play a role in the inhibition of myogenesis (By similarity).
What are the official names of this protein?
Transcription factor 23, TCF-23, Class A basic helix-loop-helix protein 24, bHLHa24.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_ACICJ
Sequence: MAMPDVSLRQLLEAGVHFGHNTRRWNPRMAPFLFGVRNQVHIIDLQQTVPMLERALREIRNVTAGGGRVLFVGTKRAAAEHVAYAAKRCGQYYVNHRWLGGMLTNWKTITNSIRKLRQMEETLAGDGQGLTKKEMLNLMRERDKLDRALGGIKEMGGLPDILFIIDTNKEKLAVEEANKLGIPVVAVLDSNSNPEGVTYPIPGNDDAIRAITLYCDLVANAVLDGISAEMAASGADIGALEELPAEAVDEDAEAHA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LPOB_DICD3
Sequence: MKKYLGIVLMALVIAGCTSRVPQTEQPATIEPAVPTPSKPQLPPSESQPLPTPPKIQVPVLDWSAAVTPLVGQMVKTDGIARGSILLLNKLKNNTNGSLQTAQATTALYNALASSGQFTMVSREQLGVARQSLGLSEEDSLESRSKAVGLARYVGAQYVLYADASGDVKSPELSMQLMLVQTGEIVWSGNGTVRQQ
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
What are the official names of this protein?
Penicillin-binding protein activator LpoB, PBP activator LpoB.
What is the protein family that this protein belongs to?
Belongs to the LpoB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: RDRP_I02A2
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPENHEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNDLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRIRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPDWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: GPMI_HELPJ
Sequence: MAQKTLLIITDGIGYRKDSDHNAFFHAKKPTYDLMFKTLPYSLIDTHGLSVGLPKGQMGNSEVGHMCIGAGRVLYQDLVRISLSLQNDELKNNPAFLNTIQKSHVVHLMGLMSDGGVHSHIEHFIALALECEKSHKKVCLHLITDGRDVAPKSALTYLKQMQNICNENIQIATISGRFYAMDRDNRFERIELAYNSLMGLNHTPLSPSEYIQSQYDKNITDEFIIPACFKNYCGMQDDESFIFINFRNDRAREIVSALGQKEFNSFKRQAFKKLHIATMTPYDNSFPYPVLFPKESVQNTLAEVVSQHNLTQSHIAETEKYAHVTFFINGGVETPFKNENRVLIQSPKVTTYDLKPEMSAKGVTLAVLEQMRLGTDLIIVNFANGDMVGHTGNFEASIKAVEAVDACLGEILSLAKELDYAMLLTSDHGNCERMKDENQNPLTNHTAGSVYCFVLGNGVKSIKNGALNNIASSVLKLMGIKAPATMDEPLF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PRR5L_BOVIN
Sequence: MTRGFTPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS
What is the function of this protein?
Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton.  Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration.  Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress.  Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress.
What are the official names of this protein?
Proline-rich protein 5-like, Protein observed with Rictor-2, Protor-2.
What is the protein family that this protein belongs to?
Belongs to the PROTOR family.
Protein: EXO1_BPT4
Sequence: MKILNLGDWHLGVKADDEWIRGIQIDGIKQAIEYSKKNGITTWIQYGDIFDVRKAITHKTMEFAREIVQTLDDAGITLHTIVGNHDLHYKNVMHPNASTELLAKYPNVKVYDKPTTVDFDGCLIDLIPWMCEENTGEILEHIKTSSASFCVGHWELNGFYFYKGMKSHGLEPDFLKTYKEVWSGHFHTISEAANVRYIGTPWTLTAGDENDPRGFWMFDTETERTEFIPNNTTWHRRIHYPFKGKIDYKDFTNLSVRVIVTEVDKNLTKFESELEKVVHSLRVVSKIDNSVESDDSEEVEVQSLQTLMEEYINAIPDITDSDREALIQYANQLYVEATQ
What is the function of this protein?
Exonuclease that plays a role in viral genome replication, DNA recombination, and host DNA degradation.
What are the official names of this protein?
Exonuclease subunit 1, Gene product 47, gp47.
What is the protein family that this protein belongs to?
To phage T5 protein D12 and to yeast RAD52.
Protein: PUR7_CALS4
Sequence: MEKKELLYEGKAKKVYKTDKEDYYIIEYKDDATAFNGLKKGVIEEKGVVNNKVSSILFEFLEKRGIPTHYVKMLKDREMLVKKVTIFPLEVIIRNYAAGSICKRLGLQEGIKFKEPVLEFCYKNDELGDPMINEYHIRALELATRDEIDLIKERAFKVNEILSEYFLSKDIILVDFKLEFGKNQEGILLADEISPDTCRFWDKNTMEKLDKDRFRKDLGQVEEAYLEILRRVQQV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: HRCA_MYCBT
Sequence: MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GMPPA_PIG
Sequence: MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPDEPLTRFLEAAQQEFNLPIRYLQEFAPLGTGGGLYHFRDQILAGGPEAFFVLNADVCSDFPLSAMLDAHRHRPHPFLLLGTTANRTQSLNYGCIVENPQTHEVLHYVEKPSTFVSDIINCGIYLFSPETLKPLGKFFQRYQQGGQLEDSSVLWPGAGTIRLEQDVFAALAGQGQIYVHLTDGIWSQIKSAGSALYASRLYLSQYQLTHPERLAKHTPGGPRIRGNVYIHPTAKVAPSAVLGPNVSIGEGVTVGEGVRLRESIVLHGATLQEHTCVLHSIVGWGSTVGRWARVEGTPNDPNPNDPRAHMDSESLFKDGKLLPAITILGCRVRIPAEVLILNSIVLPHKELSRSFTNQIIL
What is the function of this protein?
May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose.
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase alpha, GDP-mannose pyrophosphorylase 43-kDa subunit, GDP-mannose pyrophosphorylase A, GMPP-alpha, GTP-mannose-1-phosphate guanylyltransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTF_DERIN
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, DerIn-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPH1_DEBHA
Sequence: MEPKPEELEKKKVVRRKFIGKRSSVKGDEASLVKSANKTRHVGRVMNQIPQEILNDKDLNEAIRLLPSNYNFEIHKTVWNIKKNGAKRVALQMPEGLLIYSLIISDILEQFCEVETVVMGDVSYGACCIDDYTARALDCDFIVHYAHSCLVPIDITDIKVLYVFVTINIDEQHLINTIKLNFDKGSQLAVFGTIQFNPTIHSIKSKLENDEEKTMYLIPPQTMPLSKGEVLGCTSARLNKEQIKAMIYIGDGRFHLESSMIHNPEIPAYRYDPYSRKFTKEYYDQKQMIEVREDAVKIASNAKKIGLILGALGRQGNPVTLNNLETKLSAKGIQVVKIILSEIFPQKLSMFNDIDAFIQVACPRLSIDWGYAFNKPLLTPYEAMVMLENDTKWNETYYPMDYYSKEGYGRGKVPDHSNVI
What is the function of this protein?
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_ECOSM
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGLPFTITGIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKMGIHQQTTLIRHGFYPAGGGVVATEVSPVALFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLVGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFGLVEADGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_ECO55
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ATPE_SULNB
Sequence: MELMKLEIVTPNGVIFDDDVKQVTLPGSEGEFGVLPKHATLVSLLDTGVIVIEKADGSEVAVAINSGYVKVDEEKTTCIVDGAVALSGEDSDLAKALEEAKELIKKAESSSVAIASAVSKVEQIGKSF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AMNLS_MOUSE
Sequence: MGALGRVLLWLQLCAMTRAAYKLWVPNTSFDTASNWNQNRTPCAGDAVQFPADKMVSVLVRDSHAISDMLLPLDGELVLASGAALSAAGGDSDPACNPGAPLLFRNPDRFSWLDPHLWSSGTQAPGLFSVDAERVPCSYDDVLFPRDGSFRVALGPGPNPVHVRSVSAVGQTFSRDEDLTAFLASREGRLRFHGSGALRVGSQACTDASGCVCGNAEMLPWICASLLQPLGGRCPQAACQDPLLPQGQCCDLCGAIVSLTHDPTFDLERYRARLLDLFLKQPQYQGLQVAVSKVLRDAHTEIQVVLVETEHATGAAGQLGHALLQDAVAQGSVLGIVSATLRQSGKPMTADSELNQSSSGAGLAGGVAALVLLALLGTVLLLLHRSGRLRWRRHEDAEPVSAGLPLGFRNPIFDAIVFKQQPSVELPDSAQKVDILDIDTKFGCFVNPLFAGEAEAEA
What is the function of this protein?
Membrane-bound component of the endocytic receptor formed by AMN and CUBN.  Required for normal CUBN glycosylation and trafficking to the cell surface (PubMed:15342463).  The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12 (By similarity).  Required for normal CUBN-mediated protein transport in the kidney (PubMed:15342463).
What are the official names of this protein?
Protein amnionless.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Endosome membrane. Membrane, coated pit.
Protein: SYD_STREM
Sequence: MKRSMYAGHVREEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREGVMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTILNTAKTTPFEIKDGVEVSDDMRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGFIDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAYDDAMNHYGSDKPDTRFDMLLQDLTDLVKEVDFKVFSEAQAVKAIVVKGHADDYSRKDIDKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVESKLTESLQLEHNDLVLFVADTLEVANNTLGTLRTRIAKELDMIDMSQFHFLWVVDWPMFEWSEEEERYMSAHHPFTLPTQESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFKALGFTKEEASDQFGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLVSEKQLEELQLQIEHHD
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEI4_MOUSE
Sequence: MDIQPWYLKTSKLALALAIIHSKPADRSSREYTEYLASLVTQKESTWKSKLEALEAEVLQLRQKLLLSRISSGLFKNGPDVLPTLSDQEPTSSENTLTLMDDSGCVLSNEQRNEPAELSQHFVESTDPPLLPLPLEKRPRTTLENPLSSHMQFFQHLLELKKWTESSSLKVYLTHFEKDSSTVSDSVSQLLDALITFYRNPKLPFSSFWTEAVGTLARLASDFNLSNHIFKRCSKKLEEFEKTLLQAILENNSINRFQVQRYVSQSLVTLGSCSLLRKSIISLLLSEVNSFVDDLGAIDQDQGIYDVTRYENIFSLFWILEQVLQQAPQGDRTAHMDHSIPEMQTFLQKHDEVIFRLSDAFPLFAFYLWRLGVLLNSAEMETVKNESLP
What is the function of this protein?
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:20551173, PubMed:25795304, PubMed:27723721).  Probably acts by forming a complex with IHO1 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (PubMed:27723721).
What are the official names of this protein?
Meiosis-specific protein MEI4.
What is the protein family that this protein belongs to?
Belongs to the MEI4L family.
What are the subcellular locations of this protein?
Chromosome. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis (PubMed:25795304, PubMed:27723721). Located in discrete foci on the axes of meiotic chromosomes. The number of foci is highest at leptonema, decreases at zygonema and is strongly reduced in pachynema and subsequent stages (PubMed:20551173).
Protein: TRPF_MICAN
Sequence: MRIKICGITQPDQGRAIATCGATALGFILVPSSPRYVKIEQINAITAAIPDKIDFIGVFADEQPEIIQQIIVKTPLTSVQLHGKESPEYCQRLRQLLPDREIIKALRIKDRESWEKSAIYFNSVDTLLLDAYHPQLLGGTGHTLDWQALASFSPPLPWFLAGGLNPDNISEALTRLHPQGIDVSSGVERSPGDKDLKKVALLLERLQKFRDQ
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: T431_STAA8
Sequence: MNYFRYKQFNKDVITVAVGYYLRYTLSYRDISEILRERGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Transposase for insertion sequence-like element IS431mec.
Protein: ATP9_OENBI
Sequence: MLEGAKLMGAGAATIALAGAAIGIGNVFSSLIHSVARNPSLAKQLFGYAILGFALTEAIALFALMMAFLILFVF
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CYB_BRABT
Sequence: MTNIRKSHPLLKIINHSFIDLPTPSNISSWWNFGSLLGVCLMLQIVTGLFLAMHYTSDTSTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFIHVGRGVYYGSYTFMETWNIGIILMFAVMATAFMGYVLPWGQMSFWGATVITNLLSAVPYIGPALVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTMKDLLGVILLILALTLLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALLPFLHTSKQRSLMFRPITQTLYWILAADLFTLTWIGGQPVEYPFVIIGQLASILYFSIILVFMPISGHIENKILKLE
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PGM2_PONAB
Sequence: MAAPEGSGLGEDARLDQETAQWLHWDKNSLTLEAVKRLIAEGNEEELRKCFGARMEFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGGSSRRFARLAATTFISQGIPVYLFSDITPTPFVPFTVSRLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSLIDSSPLLHNPSASINNDYFEDLKKYCFHRSVNRETKVKFVHTSVHGVGHSFVQSAFKAFDLVPPEAVPEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKTKARIVLANDPDADRLAVAEKQDSGEWRVFSGNELGALLGWWLFTSWKEKNQDRSALKDTYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKTVLFAFEEAIGYMCCPFVLDKDGVSAAVISAELASFLATKNLSLSQQLKAIYVEYGYHITKASYFICHDQDTIKKLFENLRSYDGKNNYPKACGKFEISAIRDLTTGYDDNQPDKKAVLPTSKSSQMITFTFANGGVATMRTSGTEPKIKYYAELCAPPGNSDPEQLKKELNELVSAIEEHFFQPQKYNLQPKAD
What is the function of this protein?
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses.  Catalyzes the interconversion of glucose-1-phosphate into glucose-6-phosphate but with a lower catalytic efficiency.  In vitro, has also a low glucose 1,6-bisphosphate synthase activity which is most probably not physiologically relevant.
What are the official names of this protein?
Phosphopentomutase, Glucose phosphomutase 2, Phosphodeoxyribomutase, Phosphoglucomutase-2, PGM 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SYR_PECAS
Sequence: MNIQALLSEKVSQALTAAGAPADSEAQVRQSAKAQFGDYQANGVMAVAKKLGMPPRQLAEKVVQLLALEGIAEKTEIAGPGFINIFLDKQWVASQVENALNAPKLGLTPVEPQTIVIDYSAPNVAKEMHVGHLRSTIIGDAAARTLEFLGHNIIRANHVGDWGTQFGMLIAYLEKMQNESANEMDLSDLEAFYREAKKHYDEDADFAERARGYVVKLQGGDEYCRQMWRKLVDITMTQNQINYERLNVTLTKQDVMGESLYNSMLPNIVADLKAKGLAVESEGATVVFLDEYKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLNADRVLYYIDSRQHQHLMQAWTIVRKAGYVPDSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLSELLDEAYGRALKLIAEKNPQMESDELAALAKVVSIGAIKYADLSKSRTTDYVFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIQEDTLTQPITLNDEREFALATRLLQFEETITSVAREGTPHVMCSYLYDLAGLFSGFYEHCPILNAENDDVRQSRLRLALLTAKTLKQGLDTLGIETVDKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.