PharMolix/UniProtQA huggingface dataset:
Protein: DEF_HELPY
Sequence: MALLEIIHYPSKILRTISKEVVSFDSKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLIINLPQEDGVQHKEDCLEIINPKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELQKKQKHE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: THPS_SULAC
Sequence: MNFKSICLIILLSALIIPYIPQNIYFFPHRNTTGATISSGLYVNPYLYYTSPPAPAGIASFGLYNYSGNVTPYVITTNEMLGYVNITSLLAYNREALRYGVDPYSATLQFNIVLSVNTSNGVYAYWLQDVGQFQTNKNSLTFIDNVWNLTGSLSTLSSSAITGNGQVASAGGGQTFYYDVGPSYTYSFPLSYIYIINMSYTSNAVYVWIGYEIIQIGQTEYGTVNYYDKITIYQPNIISASLMINGNNYTPNGLYYDAELVWGGGGNGAPTSFNSLNCTLGLYYISNGSITPVPSLYTFGADTAEAAYNVYTTMNNGVPIAYNGIENLTILTNNFSVILI
What is the function of this protein?
May represent a new class of acid proteases.  It digests proteins and peptides in acidic solution.
What are the official names of this protein?
Thermopsin.
What is the protein family that this protein belongs to?
Belongs to the peptidase A5 family.
What are the subcellular locations of this protein?
Secreted. Note=May be linked to cells by covalent linkages through some side chains.
Protein: CLCA_ARATH
Sequence: MDEDGNLQISNSNYNGEEEGEDPENNTLNQPLLKRHRTLSSTPLALVGAKVSHIESLDYEINENDLFKHDWRSRSKAQVFQYIFLKWTLACLVGLFTGLIATLINLAVENIAGYKLLAVGYYIAQDRFWTGLMVFTGANLGLTLVATVLVVYFAPTAAGPGIPEIKAYLNGIDTPNMFGFTTMMVKIVGSIGAVAAGLDLGKEGPLVHIGSCIASLLGQGGPDNHRIKWRWLRYFNNDRDRRDLITCGSASGVCAAFRSPVGGVLFALEEVATWWRSALLWRTFFSTAVVVVVLRAFIEICNSGKCGLFGSGGLIMFDVSHVEVRYHAADIIPVTLIGVFGGILGSLYNHLLHKVLRLYNLINQKGKIHKVLLSLGVSLFTSVCLFGLPFLAECKPCDPSIDEICPTNGRSGNFKQFNCPNGYYNDLSTLLLTTNDDAVRNIFSSNTPNEFGMVSLWIFFGLYCILGLITFGIATPSGLFLPIILMGSAYGRMLGTAMGSYTNIDQGLYAVLGAASLMAGSMRMTVSLCVIFLELTNNLLLLPITMFVLLIAKTVGDSFNLSIYEIILHLKGLPFLEANPEPWMRNLTVGELNDAKPPVVTLNGVEKVANIVDVLRNTTHNAFPVLDGADQNTGTELHGLILRAHLVKVLKKRWFLNEKRRTEEWEVREKFTPVELAEREDNFDDVAITSSEMQLYVDLHPLTNTTPYTVVQSMSVAKALVLFRSVGLRHLLVVPKIQASGMSPVIGILTRQDLRAYNILQAFPHLDKHKSGKAR
What is the function of this protein?
Voltage-gated chloride channel that could play a role in the regulation of nitrate content.
What are the official names of this protein?
Chloride channel protein CLC-a, AtCLC-a, CBS domain-containing protein CBSCLC5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: P5CS2_ORYSJ
Sequence: MGRGGIGGAGLVAAVAKADVENTDSTRGFVKDVKRIIIKVGTAVVTGPNGRLAMGRLGALCEQVKQLNFEGYEVILVTSGAVGVGRQRLKYRKLVNSSFADLQNPQMDMDGKACAAVGQSVLMAIYDTLFSQLDVTSSQLLVTDRDFMDPSFGNQLRETVNSLLDLKVIPVFNENDAISTRRQPYEDSSGIFWDNDSLARLLAQELKADLLIMLSDVEGLYSGPPSDPQSKIIHTYVHEQHGKLISFGEKSRVGRGGMQAKVAAAFTASSKGIPVVIASGFAIDSIIKVMRGEKIGTLFHREANQWGCSKEATAREMAVAARDCSRHLQKLSSEERKKILLDIADALEANEDLITSENQADLDLAQDIGYDKSLVARMTIKPGKIKSLAGSIREIADMEDPISHTLKRTEVAKDLVFEKTYCPLGVLLIIFESRPDALVQIASLAIRSGNGLLLKGGKEAMRSNTILHKVITGAIPDVVGKKLIGLVKNKDEIADLLKLDDVIDLVIPRGSNKLVSQIKAATKIPVLGHADGICHVYIDKSADMDMAKRIVLDAKVDYPAACNAMETLLVHKDLNRTEGLDDLLVELEKEGVVIYGGPVAHDTLKLPKVDSFHHEYNSMACTLEFVDDVQSAIDHINRYGSAHTDCIITTDGKAAETFLQQVDSAAVFHNASTRFCDGARFGLGAEVGISTGRIHARGPVGVDGLLTTRCILRGSGQVVNGDKGVVYTHRELPLQ
What is the function of this protein?
P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.  Involved in abiotic stress tolerance.
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate synthase 2, OsP5CS2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
Protein: RUVA_BACCZ
Sequence: MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDEALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RSGA_HAES1
Sequence: MSKRKLTQNQQRRIQSNNAKTLHRHQHRHKSDIDWQDDMLGDFQDGTVVTRYAVHADVENEQGEIVRCNLRRTLKSVVVGDRVVWRKGKEQLQGVRGVIEAVQPRHNQIVRPDYYDGLKSIAANIDRIIIVSAVLPNLSLNIIDRYLVVCESSNIPAVIVVNKADLLSSEARTEVSLQLEIYQKIGYETLLISAKSGENMDKLTALLSEGTSIFVGQSGVGKSSLINYILPEVNAQTGKLSQVSGLGQHTTTSSRLYHLSQGGNLIDSPGIREFGLWHLDREQITNGYREFQYFLGTCKFRDCKHLHDPGCAIQLAVKEGKIDPLRFENYHRLITSLSETKSQRHFISAN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1410_CLOK5
Sequence: MHSFNKDIGSLGEDIAKNYLNQIGYTVLERNFRCKVGEIDIIGKDGDYICFIEVKSRYGKLYGNPCESVNYPKRLKIYKAANIYMLRKKLFKFNFRFDVIEIIFNTYNDVPSIKLIKDAFQI
What are the official names of this protein?
UPF0102 protein CKL_1410.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: C2C4D_MOUSE
Sequence: MWLLEKAGYRVRTAEARALQAHPSLVPKRQARGSPSRCNPNVLTPDRIPQFFIPPRLRDPRGAEGRVDRNPGGRNLPVACSLPHLAGREGWAFLPESPHTRRRESLFHGPRGLAAGLAPAQSRLHVSAPDLRLCRAPDSDTASSPDSSPCGSPHTPRPQSLSPDEASSADTSPYAPRRAPPLFHLDFLCCQLRPTKDSVLRLGPRGGQLRLSTEYQAGPGRLRLRLVSAEGLPRPRTRPGSGGGGCCVILRLQPRVRPGAQRSRVVQSSCNPIFNEDFFFEGLRPPDLAVRSLRAKVLDRGAGLRRDVLLGECETPLIALLPPLAGGLGPGSSLAPTHLSL
What are the official names of this protein?
C2 calcium-dependent domain-containing protein 4D.
Protein: HMG12_ARATH
Sequence: MSGASSEDSSIFARCEDVDCNKKIPVELVRMHICYAMFHRTLAARGFGTQTQAKKKPTNKKKSTTSLTDFAVFMNHFRKSFRTDYNGALVKEGSKIGWEMWKSMTEDEKKDYLDKAADEEDEDEDTVEEQADDSDDAEDNEVKETDDDN
What are the official names of this protein?
High mobility group B protein 12, Nucleosome/chromatin assembly factor group D 12.
What is the protein family that this protein belongs to?
Belongs to the HMGB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_MYCBO
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSLRIFKSEVRELQNENKAEASIETPTPVQSQRVDPSAASGQDSTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AB1C_ARATH
Sequence: MGFEPLDWYCKPVPNGVWTKTVDYAFGAYTPCAIDSFVLGISHLVLLILCLYRLWLITKDHKVDKFCLRSKWFSYFLALLAAYATAEPLFRLVMRISVLDLDGAGFPPYEAFMLVLEAFAWGSALVMTVVETKTYIHELRWYVRFAVIYALVGDMVLLNLVLSVKEYYGSFKLYLYISEVAVQVAFGTLLFVYFPNLDPYPGYTPVGTENSEDYEYEELPGGENICPERHANLFDSIFFSWLNPLMTLGSKRPLTEKDVWHLDTWDKTETLMRSFQKSWDKELEKPKPWLLRALNNSLGGRFWWGGFWKIGNDCSQFVGPLLLNELLKSMQLNEPAWIGYIYAISIFVGVVLGVLCEAQYFQNVMRVGYRLRSALIAAVFRKSLRLTNEGRKKFQTGKITNLMTTDAESLQQICQSLHTMWSAPFRIIVALVLLYQQLGVASIIGALFLVLMFPIQTVIISKTQKLTKEGLQRTDKRIGLMNEVLAAMDTVKCYAWENSFQSKVQTVRDDELSWFRKAQLLSAFNMFILNSIPVLVTVVSFGVFSLLGGDLTPARAFTSLSLFSVLRFPLFMLPNIITQMVNANVSLNRLEEVLSTEERVLLPNPPIEPGQPAISIRNGYFSWDSKADRPTLSNINLDIPLGSLVAVVGSTGEGKTSLISAMLGELPARSDATVTLRGSVAYVPQVSWIFNATVRDNILFGAPFDQEKYERVIDVTALQHDLELLPGGDLTEIGERGVNISGGQKQRVSMARAVYSNSDVCILDDPLSALDAHVGQQVFEKCIKRELGQTTRVLVTNQLHFLSQVDKILLVHEGTVKEEGTYEELCHSGPLFQRLMENAGKVEDYSEENGEAEVDQTSVKPVENGNANNLQKDGIETKNSKEGNSVLVKREERETGVVSWKVLERYQNALGGAWVVMMLVICYVLTQVFRVSSSTWLSEWTDSGTPKTHGPLFYNIVYALLSFGQVSVTLINSYWLIMSSLYAAKKMHDAMLGSILRAPMVFFQTNPLGRIINRFAKDMGDIDRTVAVFVNMFMGSIAQLLSTVILIGIVSTLSLWAIMPLLVVFYGAYLYYQNTSREIKRMDSTTRSPVYAQFGEALNGLSSIRAYKAYDRMAEINGRSMDNNIRFTLVNMAANRWLGIRLEVLGGLMVWLTASLAVMQNGKAANQQAYASTMGLLLSYALSITSSLTAVLRLASLAENSLNSVERVGNYIEIPSEAPLVIENNRPPPGWPSSGSIKFEDVVLRYRPELPPVLHGVSFLISPMDKVGIVGRTGAGKSSLLNALFRIVELEKGRILIDECDIGRFGLMDLRKVLGIIPQAPVLFSGTVRFNLDPFSEHNDADLWESLERAHLKDTIRRNPLGLDAEVTEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDVLIQKTIREEFKSCTMLIIAHRLNTIIDCDKVLVLDSGKVQEFSSPENLLSNGESSFSKMVQSTGTANAEYLRSITLENKRTREANGDDSQPLEGQRKWQASSRWAAAAQFALAVSLTSSHNDLQSLEIEDDNSILKKTKDAVVTLRSVLEGKHDKEIEDSLNQSDISRERWWPSLYKMVEGLAVMSRLARNRMQHPDYNLEGKSFDWDNVEM
What is the function of this protein?
Pump for glutathione S-conjugates.  Mediates the transport of S-(2,4-dinitrophenyl)-glutathione (DNP-GS), GSSG, cyanidin 3-glucoside-GS (C3G-GS) and metolachlor-GS (MOC-GS).
What are the official names of this protein?
ABC transporter C family member 1, ABC transporter ABCC.1, AtABCC1, ATP-energized glutathione S-conjugate pump 1, Glutathione S-conjugate-transporting ATPase 1, Multidrug resistance-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: EFTU_EXISA
Sequence: MGKEKFDRSKPHVNVGTIGHVDHGKTTLTAAISAVLSKAQGKAATKFDQIDGAPEERERGITIATAHIEYETDKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGPMPQTREHILLSRQVGVPYIVVFMNKVDMVDDEELLELVEMEIRELLSEYDFPGDDLPVIKGSALGALNGEAQWEEKVMELMNAVDEYIPEPVRDTEKDFMMPVEDVFSITGRGTVATGRVERGVLRVNDEIEIVGLTEETKKTVCTGVEMFRKLLDYAEAGDNIGALLRGVSRDDIERGQVLAKPGSITPHSKFKASIYVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIVHLPEGTEMVMPGDNIELTIELISTIAIEDGTRFSIREGGRTVGAGSVTEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_CYAP4
Sequence: MATINDHYLKLKAGYLFPEIARRVNAFAAAQPDAQIIRLGIGDVTEPLPAACRTAMIKAVEDMGDRSSFRGYGPEQGYEWLRQSIAEHDFQRRGCEIDASEIFVSDGSKCDTGNILDIFGDNNTIAVTDPVYPVYVDTNVMAGHTGAANEQGEYAGLVYLPVTAENGFTASLPEQKVDLIYLCFPNNPTGATASRAHLQQWVDYARANGSIIFFDAAYEAFITDPDLPHSIYEIPGARSCAIEFRSFSKNAGFTGTRCALTVVPKTLTAKAADGSEVEIWKLWNRRQSTKFNGVSYIVQRGAEAVYSPEGQAEVKGLVSFYLENARIIREQLSANGLAVYGGVNAPYVWVKTPSGFSSWEFFDKLLHTCHVVVTPGSGFGAAGEGYFRVSAFNSRANVEMAMQRIREKLAT
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: CYVC_VIOBI
Sequence: GLPVCGETCAFGSCYTPGCSCSWPVCTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide vibi-C.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: PTPA2_ASPOR
Sequence: MASEVSASQGVPKPKIDLSKKLSELRSNRKSQPALPSRPSREPAPVTPPLSNPPDLSSHQYARPVCRILSNHDHQLFLSSSSYSLILAFIFGLSDSVRGRATTDSKDRPVSPNVSKILAVVESIRTLLDQHPSIDQGGSRFGNPAFRDLFDDVAAQSAKWHREILGIQDSTAIEEASAYLIHSLGSRDRLDYGSGHELNFMMWLLCLRQMQLYSTADFEMIVFRVYVTYMHLMRDVQSAYYLEPAGSHGVWGLDDYHFLPFLFGAAQLVEHPYITPLAIHNNVILDEEGDRYIYLDQVRWVDSVKTVKGLRWHSPMLDDISGAKNWSKIESGMKKMFVKEVLGKLPIMQHFLFGSLIPAAPGMGEADDVQTDGHDHTHSHDHAHAQHTDHFGDCCGIKVPSTVAAGAEARKRGTGLRPIPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2P2_PROHU
Sequence: MSHPDLNKLLELWPHIQEYQDLALKHGINDIFQDNGGKLLQVLLITGLTVLPGREGNDAVDNAGQEYELKSINIDLTKGFSTHHHMNPVIIAKYRQVPWIFAIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVMEHGTKIY
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CAGCTG-3' and cleaves after G-3.
What are the official names of this protein?
Type II restriction enzyme PvuII, R.PvuII, Endonuclease PvuII, Type-2 restriction enzyme PvuII.
Protein: RR4_ORYSJ
Sequence: MSRYRGPRFKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKSSTGQVLLQLLEMRLDNILFRLGMASTIPEARQLVNHRHILVNGRIVDIPSFRCKPRDIITTKDNQRSKRLVQNSIASSDPGKLPKHLTIDTLQYKGLVKKILDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_HALH5
Sequence: MKNVAVIGAGSWGTALSLVLADNGHHVTLVARREEIAREINERHTNETYLPSIEIPSSIVATCSMEEIIDVEIIVLVVPTKAIRQAVRSLNDVLKWPVTIVHASKGIEPGSHLRISEMIEEELEPTLLKEVVVLSGPSHAEEVSLRQPTTVTVSSKSLSTTKQIQDLFMNQQFRVYTNEDLIGVEIGGALKNIIALACGLTNGLGYGDNTKAAIMTRGLAEIGRLGVKLGASPLTFAGLSGLGDLIVTCTSIHSRNWRAGQMLGKGKSPAEVEESMGMVVEGIRTTQAAHELAQKLQIEMPITSALYSVLFEGKKPEHAADELMGRVKKHEMENLHDVVSDQKND
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Protein: MGT4D_MOUSE
Sequence: MKAKNVNLLFAFVAVLLFGFSCFCISRMNQTNNQLINCRNHVLEFKEIMLRLKNKSENHHQDLMQVLYQMKRKAAHTTRSSGNFLEKKGSILSQHETLPNQFEVLKYFLPHLRTAGKLYPAIATSKGRAGVSFALGISTINRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDESYLKSVVRMVKTKFRKQVQSGVLEVISIPTLFYPQTLLDKKTKTDSESWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSLTSKNWFFIEFSVLGFIGKLFRSKDLTDFVHFFLMFYETKPIDILLDDIFLIRVCISGEPVRSCLQRKKGFRIQYRPSLFQHVGTQSSFPGREQHLKDNYY
What is the function of this protein?
May play a role in male spermatogenesis.  In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans.  The function is mediated by its lumenal domain and occurs specifically in the Golgi.  A catalytic glucosyltransferase activity is not detected.  May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D, N-acetylglucosaminyltransferase MGAT1 inhibitory protein, GlcNAcT-I inhibitory protein, GnT1IP.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
[Isoform 2]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: DCK2_FOWPN
Sequence: MAFQELCCSNLLKFENCSLLETHKKISIEGNISAGKSTLINILSDNGYNVVQEPLEQWRGNNLLDKLYKDPSRWAYTFQSHAFWTRTKTYIDALNKNKGNIILERSVFSDKYIFATALHDIGYIDDTEWNIYNEYSKWMTEFMDIKIDGIIYLKTSPDICYKRMLNRARHEENTVKIDYLNLLHDKHEKWLSENNEHEFKVPVLEINGDGDFIDDSNRQSSILSNIYDFISELYI
What are the official names of this protein?
Probable deoxycytidine kinase FPV151, dCK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
Protein: SCN4B_HUMAN
Sequence: MPGAGDGGKAPARWLGTGLLGLFLLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV
What is the function of this protein?
Modulates channel gating kinetics.  Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation.  Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
What are the official names of this protein?
Sodium channel subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RLMG_SALCH
Sequence: MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEIRGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTADYPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFSHPQLADAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGARFFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQAKVVFVDESPMAVDSSRLNVETNLPEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXD15_RAT
Sequence: MQLLCWWQILLWVLGLPARGLEEDSGHTWQEERPVPALQVGSVYLNEEEAAQGHRVQARVAEPSEASLGPRGDPMVVLSVIPGAAEDQRSTEAHDGTCSAQGDEDPRCGGRENLFGLQGAGGFQDREEEYYAEPGVAEAEPVATEDANSTDSLKSPKVNCEERNVTGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPTLGFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTGIEAKKNVVVTQADQLGPLPSTLVKTVDWLLVFSLFFLISFIMYATIRTESIRWLIPGQEQEHAE
What is the function of this protein?
Acts as a positive regulator of ciliary hedgehog signaling.  Required for cilia biogenesis.
What are the official names of this protein?
Thioredoxin domain-containing protein 15.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Single-pass type I membrane protein.
Protein: SMC_CLOK1
Sequence: MSMFLKTIEIKGFKSFADKTELIFTGGITSIVGPNGSGKSNISDAVRWVLGEQSVKTLRGGKMEDVIFAGTQFRKPLGLCQVSLTLDNEDKKLSLEYSNITVSRRLYRSGESEYYINNVQCRLRDIHELFMDTGIGREGYSIIGQGRIDALLSGKQEDRRLLLEEAAGIVKFRWRRSEAEKKLENTEVNLIRIEDILHTYEERLKPLELENKKADEFLRLSEELKDKEKTVLIYSLKKIQHKIDKLESSMERITSSNRESHLELTKLREDVNGYNIRMENIMDESTRCEKDYYDKRELINQGENKIKLLKQKIEDLEDNIKRNYLELKQIENDKIKKSEGITLQNQNLLELKNREKEVNIGILDYENNIKKIEKDIYSRENICKKLKEDKIQYFSNISKLRNHIISIKKDGENIVEKIDKLKSSYESYSKAIIISSEKKNKLLGEISNIKKNISVYQNKIDENNSGILELTNVLNLKENSLQKLNALYNTLEANYKMLVNFHKHYEGYNRTVKALMENIKNHKLDVPAQSCFLVGEIISLQKKFETCIEISLGNSISSVITNNEIIAKIIIKYLKDNKMGRATFLPISIIKGRKISNLHKFEDIKGFIGVASELVSYSKEFKDVLDYILGRTIICENIDNAFEIAKLAEYSFKIVTLSGDVVNSGGAITGGSLQKRSSNIIGRKREIEETLVKIENTKETLQVLNGDIRRIKSDKEKLHCQNEDFKEKIHLDNIELTKLHQQNDTIERETKKLIESRETANREIKLLYKNKEVNLNELQEEEKKLKEYSKEEIKNDDYILKMEEELKEGRNRITDLKEGLTSLKVKRAQISENILSSERELSRLDQEIKSMDIKNRSIVEEIKLSEKIIHKNELNMYSNEKEVKDLKQYMEKLQESIEKSHVKTIELKQKINVSNEKVDNLTLIINKKETSFHKIQLELTKLNSQKDNIYSRLKEDMNITCDGDIEYDVQIENLEEYKSKIVHLKSSISKLGVVNLGAIEEYKNLQKKITFLSSQKEDLIKSKQELKKVIDAMTEKMKGVFKENFVKLKKNFNDTFRELFKGGSADLVLTKGDELTGNIDITVQPPGKKLQNINLMSGGEKGLSAIALLFAMLKIKPTPFCILDEIEASLDDANVLRYAEFLRKFSRDTQFIVITHRKGTMEVSDVLYGVTMEEKGVSKIISLKL
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BACLD
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAYNFTKNLAADGGKILFVGTKKQAQDSVKEEAERSGMYYVNQRWLGGTLTNFETIQKRIKRLKDIEKMQENGTFDVLPKKEVVQLKKELERLEKFLGGIKEMKELPDALFIIDPRKERIAVAEARKLNIPIIGIVDTNCDPDEIDVVIPANDDAIRAVKLLTSKMADAILEAKQGEESAETEAKEAETTETTTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GATC_SYNAS
Sequence: MKISKEEVAYVAHLARLEFSESEMETFTFQMNEILLYMDKLNEVDTSGVEPLSHAIALHNAFREDKVQESLSQDLSLANAPDPRGEFFRVPKVID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL5_SODGM
Sequence: MAKLHDYYKDEAVSQLMKQFGYHSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFDRLISIAVPRIRDFRGLSAKSFDGRGNYSMGVHEQIIFPEIDYDKVDRVRGMDITITTTAKSDDEGRALLTAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.