PharMolix/UniProtQA huggingface dataset:
Protein: RS10_BORPE
Sequence: MKNQKIRIRLKAFDYKLIDQSAAEIVDTAKRTGAVVRGPVPLPTRIRRYDVLRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMRLDLPAGVDVEIALQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: HTRA_LACHE
Sequence: MVENQNNNQNQPRKKSGNKIIATAAIFGVVGGLVGGGVSYYAMDQMNNGQGNGAAQISISSSSSKVSEKSAKNGGTMTAAYNDVKGAVVSVINLKRQSASSGTDSLYNSLFGDDSDSSSSKNGKLETYSEGSGVVYMKSNGKGYIVTNNHVISGSDAVQVLLANGKTVNAKVVGKDSTTDLAVLSIDAKYVTQTAQFGDSKHLEAGQTVIAVGSPLGSEYASTVTQGIISAPARTISTSSGNQQTVIQTDAAINPGNSGGALVNSAGQVIGINSMKLAQSSDGTSVEGMAFAIPSNEVVTIVNELVKKGKITRPQLGVRVIALQGIPEGYRSRLKIKSNLKNGIYIAFVSRNGSAANAGIKSGDVITKVDGKKVEDVASLHSILYSHKVGDTVNVTVNRNGKDVDMKVKLEGN
What is the function of this protein?
Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein.  It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (By similarity).
What are the official names of this protein?
Serine protease Do-like HtrA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YD544_YEAST
Sequence: MSLRPCLTPSSMQYSDIYIHTTPHPHTPHHTHHTHTTPTPTPHPHTHTPTPERSLSLRLRQAKPDQPVSQITLHYPTSPLVTLTHSTIPPQPPSISLCTTTNRPSTITVTLQLPISNSTTTYPTISHLLLTILLFYPPLLKR
What are the official names of this protein?
Putative uncharacterized protein YDR544C.
Protein: RL16_SHISS
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ENGB_GEOSL
Sequence: MVNITSAEFVTSGTRPEHYPPGDLLEIAFVGRSNVGKSSLINVLVNRKSLVRTSSTPGRTQLINFFRVNGSLMLVDLPGYGFARVPPEVKRQWGPMVETYLAGRSCLACVVLIVDVRRTPAEEDRLMLQWLRAYDIPVLVVITKCDKVSKNERAKQASLISRTLGLAPDEMAFFSALSREGRDAIWARIEAIMAEGHSPSVDGAPE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HSLV_SHIFL
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBN2_BOVIN
Sequence: MAEPRRVAFISLSPVRRREAEFPGTEREPEYPREPPRLEPQPYREPARTEPPAPREVAPRSDAQPPPREKPLPQREVSRAEPPMSLQREPPRPEPPPPPLPQLHLQPPPPRESTSRAEPQPRPPRETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKPVYTEDPFNDDHQERQEVEMLAKKFEMKYGGKPRKHRRDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDTTDNQKHKPPKIPKIKEDDIEMKKRKRKEEGEKEKKPRKKVPKQLGVMALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESNPKTPLNFSTSSLNKPPSAAVALGNDVSDLNLTSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDAASNGSPLSESGGENGNTTQPTYASQVMPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARNQAKCAKFQTDEEREKNGSEEDDEEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAPKPKVKECSPKKDQKTPASSVASVGGPSTSSSTSAVASTSSGSTPVQETICLDDSLDEELSFHPPALDLVSEALAVINNGNKGPPAGSRISMPTAKPRPGLREEKLASIMSKLPLATPKKLDSTQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSSQTHVSSSSQAQVAASSHTLGTSEAQDASPLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSPLTKTSDKPLMYRLPLSTPPPGNGSQGSHSLVSRTVPSTTTSTNYLAKAMVSQISTQGFKSPFSMAASPKLASSPKPATSPKPLPSPKPSASPKPSQSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQSSHSSSNNPVHKQPSGMNISRQSPTLNLLPLNRTSGLPSTKNLQAPSKLTNSPSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPSSASGSSVVAASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGAQHAAALSHAPLPTHVQQTFNDGGQSKGDTKLPRKSQ
What are the official names of this protein?
Ubinuclein-2.
What is the protein family that this protein belongs to?
Belongs to the ubinuclein family.
Protein: HIS1_CAMJ8
Sequence: MQENTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGYCRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCMLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSKEKQALVDKIMLRVAGVMQARESKYIMLHAPKEKLDKIQALLPGVERPTILPLAHDEKNVALHMVSKENLFWETMEALKEEGASSILVLPIEKMLK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSP6_CHLRE
Sequence: MAADVGQALAFLQQVKTTQGASIYEGLKAALAKVLEDRPVNAVEALETSVLSTPPAANLSVPLVPAASAAAAAAAVAKASLFGDPEPVLDPESGEPIDPDAPNEFECEDVEGDGDLLDGLGVGLGRQEMYAAMLAVKRLGEDAKRGVSTVRFFGKFFGTQADYYVFETTLQSNPDMPEAPEGTIPLEPYGEGVNAYIYFVSNTLGGPLQQLPYVTPEQIKASRLLRRYLTGRLDAPVSAFPAFPGNEANYLRALIARISAATVCCPRGFFTADDDSAELSANDEWVPLKGREMALPVNWSHRYAHLKGQGRTVTHKRDPPDEEEEPEKNFWTAEEMEAGPPPLATLDTDAPLPAATGDKVPPPAWSPVFASASVTTRNQVAGVRSNRWPGAVCACAGRHFTSMYVGWGIKAGGEWSPCPPPPPVPQWGAPAAGVEGGQQLLLECNDLPPKPAPPEEEDE
What is the function of this protein?
Flagellar radial spokes contribute to the regulation of dynein arm activity and thus the pattern of flagellar bending.  They consist of a thin stalk, which is attached to the a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules.
What are the official names of this protein?
Flagellar radial spoke protein 6.
What is the protein family that this protein belongs to?
Belongs to the flagellar radial spoke RSP4/6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Note=Radial spoke.
Protein: ATPL_CLOD6
Sequence: METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPEAKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFPL_SALTY
Sequence: MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSAGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SURE_PARXL
Sequence: MRILLSNDDGYLAPGLAALYEALKPIADVTVMAPEQNCSGASNSLTLSRPLSVLRSANGFYYVNGTPTDSVHIALTGMLDHRPDLVVSGINNGQNMGEDTLYSGTVAAATEGIMFGVPAIAFSLVDKDWVHLEDAVRVSAEIVAHYLEQPLPGHPLLNVNIPNLPYDQLGDWQITRLGKRHPSQPVIRQTNPRGEPIYWIGPAGSARDASEGTDFHAVANGHVSITPLQLDLTHTQMLPAARDWARAGSGAS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SYNJA
Sequence: MTDRVRLYEIAREMGCDNREVLEVCEQLGIPFKSHSSTISPEQAELVRSKLSEPRVVKPTRPRLRPKLQPESSQPQPPVEAKASERPQHIVGIRRPAPAQQQAAAGEASSSKPSPQRPDQLSSEKGAAGGSLELIGPPRRQVDPPARPAAQEPQPAAASTRPEAAAKAGSPEPSPAPAAKRPTVLPPPRRAASGPEPPQRAPESRRPGLAEAPSPSGARTSPPVEEKVSLPQAEQRPRPQLVGAPVRPGTRPEPRSPVAKKEESSDSGKADEAPRPQRRLELVGPPTRPVAKPLPPEPDASPRLPEGIPEERPTPVLAEAPVRPAAPKLKRKTVEEEDEELQALERRAGRTQAKRKRSRRREEGDGDVLDLDPLTVLSSVKQAELNALKPLARPTAKPPSYRPPAAAARPRPAAERPQRPSASAEATAPEAAAESLPEEKVLLLEGSLTVQELARRLRVAETEIIKTLFFKGVRVTINQVLDESLAESVAKELGYEVRRPEAEPKAKKTEILDLEDIDHLVPRPPVVTIMGHVDHGKTTLLDAIRHTNVAQREAGGITQRIGAYHVDVDFEGQKRRIVFLDTPGHQAFTAMRARGARVTDIAVLVVAADDGVQPQTLEALSHARAAQVPIIVAINKIDKPGSQPERVKQQLAEHGLLPEEWGGDTPMVEVSALTRRNLDALLEMILLVADVAELQANPNRPARGTVIEAHLDKARGPVATLLVQNGTLRVGDTLVAGAVLGRVKAMMDDRGQRLQEAGPSSAVQLLGLEEVPAAGDEFQVYADEKEARRIAEERAEALRQARLQQALLSRRVSLGSISAKAQEGQLKELNLIIKTDVQGSAEAIQTALQDLPQEEVRLRVLLAAPGEITETDVDLAAASDAIILGFNTSFAPGARQAADDKGVDVREYDIIYNLLDDLRAAMEGLLEPEEVEEPLGQAEVRKVIPISRGAVAGSYVLSGKVQRNALVRVRRKGEVVYQGRLDSLKRFKDDVREVAAGFECGIGIEKFDAWQEGDLIEVYQMVTKRRTLAPA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_PSEMY
Sequence: MLRSLTRRLLKLLFWLMLASALLVLALRWLPPPGTALMLERKIESWGSEQPLQLKRQWRPWNELPDHLKMAVIAAEDQKFAEHWGFDVGAIQAALAHNQSGGSLRGASTLSQQVAKNLFLWSGRSWPRKALEAWFTALIELFWPKERILEVYLNSVEWGDGIFGAEAAAQHHFGVGAPYLNRQQASQLAAVLPNPRRWSAGRPDAYVNRRAAWIRQQMTQLGGSHYLNQLKPRYPEWWPRWL
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ATPA_SALTI
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CMOB_SHESR
Sequence: MISFSSFYQQIADSNLQHWLETLPAILGRWQREHKHGNLPKWEKVLNKLHYPAPDQVDFVSSVTVGTGEQLTPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVSPHISPLQNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSPLFLCQFEAVKRLSGENHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLVEYLDPNDITKTIEGYPAPKRATIIAVKNQPNQDLT
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ISPD_MOOTA
Sequence: MPFLSMIIAAAGRGRRLGREVNKVFLPLAGKPMLAYSLAVAVASPLVDEIIIVTRPDDIPLCRQVVAGEGAGKVKAIVAGGAERQDSIAEGLKAVARAAEWVAVHDGARPFLTPALLEKTILAARNTGAAIAALPVKETIKQGGEAGIVAATLDRKGLWSAQTPQVFRREWLVDAYREAAEKGWQATDDAALVERLGYPVKLVPGEETNIKITTPGDLVLAGALLAGEK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PG038_VACCC
Sequence: MVYKLVLLFCIASLGYSVEYKNTICPPRQDYRYWYFAAELTIGVNYDINSTIIGECHMSESYIDRNANIVLTGYGLEINMTIMDTDQRFVAAAEGVGKDNKLSVLLFTTQRLDKVHHNISVTITCMEMNCGTTKYDSDLPESIHKSSSCDITINGSCVTCVNLETDPTKINPHYLHPKDKYLYHNSEYGMRGSYGVTFIDELNQCLLDIKELSYDICYRE
What is the function of this protein?
Plays a role in immune evasion.  When secreted, inhibits T-cell activation by preventing the binding of host CD80 and CD86 to soluble CTLA4 and CD28.  In the infected cell, may inhibits host NF kappa B activation.
What are the official names of this protein?
Early protein OPG038, Protein M2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG038 family.
Protein: FOLD_ALKCK
Sequence: MAEPMILDGNDVSKRIKDKLALQVAALEQKGVRPCLATILVGDDPASATYVRMKGNACKRLGIESKKIELPKETTTKELLAVIRELNNDSSVHGILLQHPVPSQIDERAAFDEIAIEKDVDGVTTLGFAQNAFGFAHYPSCTPAAILAILDHYQLPIEGKHAVVVGRSPILGKPVSQMLLNRNATVTICHSRTENVSDFVEKADIVVAAVGKPNFIQGEWIKSGAVVLDAGYNKGNIGDCEYDGCAQRASAITPVPGGVGPVTISMLLKHTVEAAERSV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TYSY_SHEDO
Sequence: MKQYLALMEHILAHGAVKTDRTGTGTRSVFGYQMRFDLNQGFPLVTTKKCHLRSIIHELLWFLQGDTNVAYLHEHNVSIWDEWADDKGNLGPVYGAQWRSWPTQSGKAVDQISQIIEQIKTQPDSRRLIVSAWNVGELDKMALAPCHALFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTKLQLSREPHALPQMNILRKPESIFDYQFDDFELVNYQPHPHIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_METCA
Sequence: MQDTIPVLTIDGPSGAGKGTAARAVAARLGWNFLDSGAIYRALAVAAVDRGVSREDESALAALAASLDLVFGADSTARILLWDADISGRIVTEECGNLASKLAAFPAVRQALLDKQRGFRRPPGLVADGRDMGTVVFPDAPYKVFLTASAEVRARRRYNQLKEKGMDVSLAHLTEEIEERDRRDRERQIAPLRAAADAVVIDSSDLSVDEVIQVCLSVVQSH
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIOD_CHRVO
Sequence: MKILVIGAGPAGLVFASQLKQARPLWAIDIVEKNDEQEVLGWGVVLPGRPGQHPANPLSYLDAPERLNPQFLEDFKLVHHNEPSLMSTGVLLCGVERRGLVHALRDKCRSQGIAIRFESPLLEHGELPLADYDLVVLANGVNHKTAHFTEALVPQVDYGRNKYIWYGTSQLFDQMNLVFRTHGKDIFIAHAYKYSDTMSTFIVECSEETYARARLGEMSEEASAEYVAKVFQAELGGHGLVSQPGLGWRNFMTLSHDRCHDGKLVLLGDALQSGHFSIGHGTTMAVVVAQLLVKALCTEDGVPAALKRFEERALPLVQLFRGHADNSRVWFETVEERMHLSSAEFVQSFDARRKSLPPMPEALAQNLRYALQR
What is the function of this protein?
Catalyzes the oxygenation of the 6-position of protodeoxyviolaceinate to form proviolacein.
What are the official names of this protein?
Protodeoxyviolaceinate monooxygenase.
Protein: DUT_ACIBC
Sequence: MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GPSB_STAA3
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: ATG18_NEUCR
Sequence: MTGGTLNFITFNQDYSCLAVGTSKGFRFYHTDPFSKIFSSDEGNVSIIEMLFSTSLVALILTPRQLEIQNTKRASVICELTFPSAVLAVRLNRKRLAVVLECQIYLYDVSNMNLVQTIDTSPNPNAICALSPSSDSCYLVYPRPNPREDVGAKAPAHLPPPSQYVPPKRGDVLVYDALNLKTVNVVEAHKSPLCAIALNHDGSMLATASETGTIIRVFSLPQGQKLFQFRRGTVPTSIYSMSFNLSSTLLCVSSTSDTVHIFRLLNTQKNANALPGGGPAQGTRSRSFDVNDPSPHKGEVPSAGNGNNGSGSHKREPSGSFGNMLRRSSQMMVRGVAGVASSYLPQSVAEMWEPERDFAFIKIPKSSNNRAGGLSATPLRSVVAMSSSSPQVMVVTSDGGFYVYNIDMEKGGEGYLVKQFSVLDGDDKLTNSDYGA
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct apg-7/atg9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: OSPC_BORBU
Sequence: MKKNTLSAILMTLFLFISCNNSGKDGNTSANSADESVKGPNLTEISKKITDSNAVLLAVKEVEALLSSIDEIAAKAIGKKIHQNNGLDTENNHNGSLLAGAYAISTLIKQKLDGLKNEGLKEKIDAAKKCSETFTNKLKEKHTDLGKEGVTDADAKEAILKTNGTKTKGAEELGKLFESVEVLSKAAKEMLANSVKELTSPVVAESPKKP
What is the function of this protein?
A major immunodominant protein in mammalian hosts (PubMed:8098841, PubMed:8478109, PubMed:8225587).  Required for the initial stages of mammalian infection (PubMed:14970347, PubMed:16714588, PubMed:20199597, PubMed:28873507).  Interaction with tick I. ricinus salivary protein Salp15 protects the bacteria from antibody-mediated killing in vitro and in vivo (PubMed:18752445).  Inhibits macrophage-mediated phagocytosis of the bacteria (PubMed:26438793).  Binds human plasminogen; this probably confers an extracellular protease activity on the bacteria that allows it to traverse tissue (PubMed:20199597, PubMed:22433849).  Binds human complement C4-B, which may inhibit the complement cascade (PubMed:28873507) (Probable).  Experiments in mice suggest it may play another role after initial infection (PubMed:27611840) (Probable).
What are the official names of this protein?
Outer surface protein C, pC, P23.
What is the protein family that this protein belongs to?
Belongs to the OspC lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: AC4CH_HAEIE
Sequence: MQPNDITFYQRFEADILAGRKTITIRDKSESYFKAGDILRVGRFEDNQYFCTIEVLSVSPITLDELTEQHAKQENMGLAELREVIKTIYPNESEFWVIEIRLVN
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: NUSB_SHEFN
Sequence: MKPSERRKARRLAVQAIYSWQLSQNKVADVEHEFLTEQNTDGVDVAYFRELLTGVASKTSQIDELLKPHLDRKFEEVSPVEKAIVRLATYELTFRKDVPFKVAINEGIELAKAFGAEDSHKFVNGLLDKLVKHK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y3612_PARL1
Sequence: MSGKLGDDALDILFRDARTHNGWKAEPVSDETLRALYDLMKWGPTSANCSPARIIFVKSKEAKEKLAPALSEGNLKKTMAAPVTAIIGYDVEFYERLPELFPHDPTAKNWFNWSKEWAEQTAFRNGSLQGAYFMIAARSLGLDCGPMSGFDMRKVDDAFFAGTTVKVNFLCNIGHGDPSALFARSPRLSFEDACKII
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase Plav_3612.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: RTL3_ORYSJ
Sequence: MESPPHATASADEMPSIWKEQHAQDAPPGFVPPMGPGEVAAVESLLGYEFRDKALVEEALTHGSFYYPYRPGVTYERLEYLGDAVLTCVVSREVFLTYGQLQPGPLTRLRAANVDKEKLARVAVVHGLHHFLRHKAPNLDGQITDFIEELSMYPIHSNGLLDPPKVLCDVVESLIGAIYCDSNFNQEIVWQVFQKLADPLISLETLGKHPVSELFEFCQKTRRGVKIVKDEWDKNLTVEVLIDGEMVGRATYAQKKEIAQNRAAKAALDKLKETLGQSQTEPMSAEVSEQFNKIDLTGS
What is the function of this protein?
Cleaves double-stranded RNA (dsRNA).
What are the official names of this protein?
Ribonuclease 3-like protein 3, Ribonuclease III-like protein 3, RNase III-like protein 3.