PharMolix/UniProtQA huggingface dataset:
Protein: PDI1_SCHPO
Sequence: MKISNLLAAFLAFSGGFFCASAEVPKVNKEGLNELITADKVLMVKFYAPWCGHCKALAPEYESAADELEKDGISLVEVDCTEEGDLCSEYSIRGYPTLNVFKNGKQISQYSGPRKHDALVKYMRKQLLPTVKPISKDTLENFVEKADDLAVVAFFKDQKLNDTYTEVAEVMKDDFVFAASDDKELAKSLGSNFPGIVAFTKDAAQDSDKLVYTGDWDPASIADFIGVSSIPLLDELNQMTFGKYQQSGLPLGIIFYNSTESRDELYDVFQPLAKKYQDTLRFAFLDAVRYGAVAKQMNVESDWPAFVIANLKSMLKYPFPTTELTAKAMTKFVGDFVDGKLQPKIKSQPIPESQEDLVVLVADNFDDIVMDETKDVLVEFYAPWCGHCKNLAPTYEKLAEEYSDDSNVVVAKIDATENDISVSISGFPTIMFFKANDKVNPVRYEGDRTLEDLSAFIDKHASFEPIKKEKESVPAPDLEDQVAVEDEMADEL
What is the function of this protein?
Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.
What are the official names of this protein?
Putative protein disulfide-isomerase C1F5.02.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS17_MAGMM
Sequence: MAKRIMQGVVVSDKMDKTVVVLVERKVRHPLYGKIVRQSKKYKAHDEENQYRTGDMVMIQESRPLSKDKNWVVTERTAVAVEG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MAOX_RAT
Sequence: MDPRAPRRRHTHQRGYLLTRDPHLNKDLAFTLEERQQLKIHGLLPPCIVNQEIQVLRVIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANLNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEKARQKIWLVDSKGLIVKGRASLTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEECYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHINDSVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYSWPEEVQKIQTKVNQ
What is the function of this protein?
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate.
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_ACTSZ
Sequence: MSRFDTLFAQLQAKNEGAFVPFVTLCDPDFDRSFDIICTLADNGADALELGFPFSDPLLDGPVIQAANNRALNAGCSTEKSFRLLAKVRSKYPEIPISLLLCANLIYAQTLDKFYQRCAEAGVDAVLVADIPLLACKDYVTAAKKHGIQPVFICPPNADEKTVAGVASHTEGYTYLVSRAGVTSAENQSHAANLDTLVERLKAHNAAPILQGFGIARPEQVKQALTLGTSGAISGSATVKIIEKNLDNHPACLQELARFTREMKAATHV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CYB_NAJNI
Sequence: MSNQHALLMFNLLPVGSNISTWWNFGSMLLTCLMLQTITGFFLALHYTANINLAFSSVIHITRDVPYGWIMQNLHAISASLFFVCIYIHIARGLYYGLYLNKEVWLSGTALLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTLTTWLWGGFSINDPTITRFFALHFILPFIIISLSSIHIILLHNEGSNNPLGTNSDIDKIPFHPYHSYKDMLMATTMITLLFLILSFAPNLLNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALIMSVMILTTMPFTHTSHTRSMMFRPLSQILFWTLIATFITITWTASKPVEPPFITISQTTSIIYFFFFITTPLLGWAENKMMMMNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BTUD_SALCH
Sequence: MSQLMQLKDVAESTRLGPLSGEVSAGEILHLVGPNGAGKSTLLARMAGLTSGEGSIRFGGAPLEAWATATLAQHRAYLAQQQNPPFAMPVWHYLTLHQPDKTRTGQLNEVADMLGLGDKLGRSVNQLSGGEWQRVRLAAVVLQIHPDANPVGQLLLLDEPMNSLDVAQQNALDRVLHHLCQAGIAIVMSSHDLNHTLRHAHKAWLLKRGKLIACGRREEVLTPSYLAQAYGLRFRRLDVEGHPMLISAT
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL33_ELUMP
Sequence: MASKERQTILLACTECKNKNYYYARGKKKEFKLELNKFCKACGKSTKHKEGKAN
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TYSY_LEVBA
Sequence: MLEEAYLDLAKTVLTTGHEKTDRTGTGTISLFGYQMRFNLQEGFPLLTTKKVPFGLIKSELLWFLRGDTNIRFLLQHHNHIWDEWAFQRYVDSPEYHGPDMTDFGRRSLVDADFNQRYQAEKKAFCDRIVTDQAFGDHFGDLGLVYGSQWRAWQGHQGETIDQLANVIETLRTHPDSRRMIVSAWNPADVPSMALPPCHTLFQFYVNDGKLSCQLYQRSADIFLGVPFNIASYALLTSLIAKEVGLEVGDFVHTLGDAHIYSNHVEQIKTQLARTPHAAPQLWLNPDKSSIFDYEMSDIKVTGYDPEPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFT_LISIN
Sequence: MMEKMILGRYIPGNSWLHRIDPRAKITAVMAFIAIVFLANNWLTYALMFAYVLYLVLTSKVPFLFFIKGLQPIFWLILITLLLQVFFTKGGTVLVDLGLLQITTLGLANGAMMFCRFVLIIFMTTLLTLTTSPIELTDGLEKILAPFRLVHLPVHELALMLSISLRFIPTLMDETEKILKAQKARGVEFTSGKWSDRIKAIIPLLVPLFISAFKRAEDLAIAMEARGYRGGKGRTRFRLLRWRFADTCLLISLAVLSGLLFWLRS
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LSM4_SCHPO
Sequence: MLPLTLLNATQGRPILVELKNGETFNGHLENCDNYMNLTLREVIRTMPDGDKFFRLPECYIRGNNIKYLRIQDEVLSQVAKQQAQQRENRGSRFRGRGQRGRGNYGHTAPNRRGRGRGGHM
What is the function of this protein?
Binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
Probable U6 snRNA-associated Sm-like protein LSm4.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI_LEIME
Sequence: MSDYFSKLKEHVVESTEINGCTPSIATATFNAPYEVARKTKMLGVTDSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHSDDNFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRDLHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGISTDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSGMSGDAIENMIPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_RHOPS
Sequence: MTSSRDALSIAQALLRCPSVTPADAGALGVLETLLKDAGFTAHRVTFSEPGAADIDNLYARIGDGAPHLCFAGHTDVVPPGDADAWSHGAFSGDVEGGLLYGRGAVDMKGGIACAVAAVLDHLAAHGGRPKGSISFLITGDEEDVAVNGTVKLLQWAADRGETFDHCIVGEPSNVEAIGDTIKIGRRGSQSGMLIVDGLQGHVAYPHRASNPIPDIAALITALNDEPLDQGSAQFQPSNLEFTSVDVGNPATNVIPAQARAKFNIRFNDHHTQDSLKALIEQRLAAACGNRIRARIEWLPSNADVFVTKPGNFTDLVTASIADVTGRTPDLNTGGGTSDARFIAKYCPVVEFGLVGQTMHQIDERTPVADLDQLTAIYRGVLERYFKS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: NHAS2_SYNY3
Sequence: MIKLPVLLADINIQSLPTEPELILNNLAITTLVENLIILLLVATLVALVARWLKIPYVIGLVLAGLAIPRGLSVGLNPELILNFFLPILIFEAAINTDISRLRSTIKPITVLAGPGVVISAAITAVLLKIGLGLAWVTAAGVSVILTITDTVSVIAAFRSVPVPRRLATIVEGESMLNDGVAMVLLSVITTIHIQGGFSAGEGIRQIFVAFVGGGLVGLGLGYLCVGLFRQLNDDLSDILLTVSVSLGTFQIGQMLGVSSAIAVVVAGLVIGNLALKQTSASIKVTLLSFWEYAGFGVNTLIFLLVGIEVYPSILLSTIPAALIAIVAYQIGRVFSIYPLLYLLSFFDRPLPLRWQHVLIAGNVKGSLSMALALALPLTLPGRDQVVTLVFSTVMVSLIGQGLSLPWVVKKLQLSKPSPLAQKIAMLQLNLVTAKAAQGELKYLLEAGSLPKFLYEELFADYQARIANSEQELREFYNQRNLIFSEGEVEKKYIDGLYRRLYIAEKSAINDALAKGILADDISDEYLQVLNEKLLALQDD
What is the function of this protein?
Required for Na(+) uptake into the cell, especially at low external Na(+) concentrations or low Na(+)/K(+) ratios.  May be part of a sodium cycle that permits re-entry of sodium into the cell.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaS2, Sodium/proton antiporter NhaS2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CUTA_YERPY
Sequence: MSDSDAMTDPNAVSYSNAIVVLCTAPDEASAQNLAAQVLGEKLAACVTLLPGATSLYYWEGKLEQEYEVQLLFKSNTDHQQALLTYIKQHHPYQTPELLVLPVRDGDKDYLSWLNASLL
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX9A1_ANEVI
Sequence: MKSIFLVFFAVCLVKAEAGKGRKREPNIINPPCRECYVQDSSGNCVYDKWGCGGARKREPNIINPPCRECYVQDSSGNCVYDKWGCGGARKREPNIINPPCRECYVQDSSGNCVYDKWGCGGARKREPNIINPPCRECYVQDSSGNCVYHKWGCGGARK
What is the function of this protein?
Inhibits ion channels.
What are the official names of this protein?
U-actitoxin-Avd13a/b, U-AITX-Avd13a/b, Peptide toxin AV-1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone structural class 9a family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RFPLB_HUMAN
Sequence: MAKRLQAELSCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLCRDVVKVPALEEWQVSVLTLMTKQHNSRLEQSLHVREELRHFREDVTLDAATASSLLVFSNDLRSAQCKKIHHDLTKDPRLACVLGTPCFSSGQHYWEVEVGEVKSWSLGVCKEPADRKSNDLFPEHGFWISMKAGAIHANTHLERIPASPRLRRVGIFLDADLEEIQFFDVDNNVLIYTHDGFFSLELLCPFFCLELLGEGESGNVLTICP
What are the official names of this protein?
Ret finger protein-like 4B, RING finger protein 211.
Protein: RL22_LACGA
Sequence: MAEQISSAKAEARTVRIAPRKARLVVDLIRGKSVAEALAILQFTPRAASPIVEKVLKSAIANAEHNYDLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSEKND
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RNC_COXBR
Sequence: MNHLNKLMERLGHQFNNLELLKIALTHCSSGADNNERLEFLGDSVLGFIIASELYQRRPQAREGDLSRMRASMVNGDELAQMSTKLGINEYLQLGVGEQKSGGKRRRSILADALEAIVGAIYIDAGLETCRRCVLNWYGERVDDLSKLSPKKDAKSLLQEWLQARRLPLPTYEVKITGEAHAQTFTVNCYVKGLPHKTEGVNTTRRRAEQIAAKRFLELLDDGKGDGITERDQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG20_SCHPO
Sequence: MAQDDSYEEKPEVISSDSGGSGYSTEIQIVGTVTSSDGSYVEYEIVHQKRSVWRRYSDFESLVKLMRRQYPAAIVPPIPGKQSLLSYAKHPRKAKSDAEFLNFRSRMLELFLRQCLLHPCIRSNPIFDKFIHSTVSWHVTLSSLDLPKDSNTDPLRLPPIATEHDPFAHLRSSMPLVMANSLSPPSSRALKPIHSLSNPSTASSLEPSSPLGSEDECHPPTSDMQPTHELNESPSTPTAPDFPHYNSSPSELSPTQRRSSISNGKDAPSPVLKDLTSYTQEVIVCRKFLHHSLSPSIHSTLSSISKMESCLSKLGSAFHSLTALNEIQLANHLQVIANAFEFSGMYAKEFEQEFNSSVYEKMVQSMQLAKCAADALKYKQLKIQQRDFLQDQLIHSNTMSATDSMVAASPTIHPATRLNTIQRAVVSQAKKGYTIFGRLQNVLHDFVEGETSISKESLQQHKNTIENQLAAANWDCQKIDEFMDAELKFYKECQTSQWEEIIKSVHECIYKWAQTNLQRWLRTREELENLSKDI
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Functions in protein retrieval from the endocytic pathway (By similarity).
What are the official names of this protein?
Autophagy-related protein 20.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RL29_SYMTH
Sequence: MKVKEIREMSTEEIKAKVAELKEELFNLRFQLAVNNLENTARIREVRRAIAQCKTVIRERELKAQGEVKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UBIE_BURP0
Sequence: MSKTHFGFETVEENEKAKKVAGVFHSVASNYDLMNDLMSAGLHRAWKAFTIAQANVRPGGKVLDIAAGTGDLTKAFAKAAGPTGEVWHTDINESMLRVGRDRLLDKGVVTPSLLCDAEKLPFPDNYFDVVTVAFGLRNMTHKDSALAEMRRVAKPGGRVMVLEFSKVWEPLKKAYDVYSFKVLPWLGDKFAKDADSYRYLAESIRMHPDQETLKTMMEQAGLDAVKYYNLSGGVVALHVGTKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MPS4_CAEEL
Sequence: MTFPKENINNYASSSFNYKYLIEEFLQWSSSCNRISYPTKYFDFLLVIIMTFVFLCLVYLLIWIEVLLNSSRPDPKHRVYYPRTNFWQRTD
What are the official names of this protein?
MinK-related peptide, potassium channel accessory subunit protein 4.
Protein: CLPP_HELPG
Sequence: MGYIPYVIENTDRGERSYDIYSRLLKDRIVLLSGEINDSVASSIVAQLLFLEAEDPEKDIGLYINSPGGVITSGLSIYDTMNFIRPDVSTICIGQAASMGAFLLSCGAKGKRFSLPHSRIMIHQPLGGAQGQASDIEIISNEILRLKGLMNSILAQNSGQSLEQIAKDTDRDFYMSAKEAKEYGLIDKVLQKNVK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMB_MYCTO
Sequence: MSRVLLVTNDFPPRRGGIQSYLGEFVGRLVGSRAHAMTVYAPQWKGADAFDDAARAAGYRVVRHPSTVMLPGPTVDVRMRRLIAEHDIETVWFGAAAPLALLAPRARLAGASRVLASTHGHEVGWSMLPVARSVLRRIGDGTDVVTFVSSYTRSRFASAFGPAASLEYLPPGVDTDRFRPDPAARAELRKRYRLGERPTVVCLSRLVPRKGQDTLVTALPSIRRRVDGAALVIVGGGPYLETLRKLAHDCGVADHVTFTGGVATDELPAHHALADVFAMPCRTRGAGMDVEGLGIVFLEASAAGVPVIAGNSGGAPETVQHNKTGLVVDGRSVDRVADAVAELLIDRDRAVAMGAAGREWVTAQWRWDTLAAKLADFLRGDDAAR
What is the function of this protein?
Involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM).  Catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2).  PimB also catalyzes the addition of a mannosyl residue from GDP-Man to the position 6 of phosphatidyl-myo-inositol bearing an acylated alpha-1,2-linked mannose residue (Ac1PIM1) to generate monoacylated phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (Ac1PIM2).  The addition of the second mannosyl residue by PimB preferentially occurs before the acylation of the mannosyl residue transferred by PimA.  Also able to transfer a mannosyl residue from GDP-Man to the position 6 of a phosphatidyl-myo-inositol (PI), but this reaction is very slow.
What are the official names of this protein?
GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase, Phosphatidylinositol alpha-mannosyltransferase, PI alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: PIOS1_HUMAN
Sequence: MFRRLTFAQLLFATVLGIAGGVYIFQPVFEQYAKDQKELKEKMQLVQESEEKKS
What is the function of this protein?
Plays a role in regulation of the unfolded protein response triggered by endoplasmic reticulum (ER) stress resulting from the presence of unfolded proteins in the ER lumen.
What are the official names of this protein?
Protein PIGBOS1, PIGB opposite strand protein 1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RLME_ACIF2
Sequence: MARSKSSEKWLKEHFKDPFVQRAMKEGYRSRASYKLLEIQQKDHLIRPGMRVLDVGAAPGGWTQVAAPLIGRKGRLVAVDRLAMDPVADATVICGDVYDDAILAACQEALPGGADLIMSDMAPNMSGIASVDQARAIDLAELALDMAHRWLVPGGALLIKVFMGSGAEELRRALRRDFKKIVVRKPEASRARSTEQYWLALDFQGVAQERLDNGGASSL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_ROSDO
Sequence: MAMKIRLARGGSKKRPFYRIVAADSRMPRDGRFIEKLGTYNPLLPKDSEERVKMDAERVQYWLGQGAQPTDRVARMLEAAGLREKAERNNPKKGTPGKKAQERAEEKAAKAAAPAEEEAAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y8443_DICDI
Sequence: MVFGTVKEVSVNFIESIFKTFKIVEEISNTNLINCTFNNNNPIQQSNSVSIERFWKI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289491.
Protein: FADX_VERFO
Sequence: MGAGGRMSVAPNNSKCEKKESRSVKRVPHTKPPFTLGQLKQAIPSHCFKRSLLRSFSYVVYDLSLSFIFYSIATTYFHLLPSPITYIAWPVYWAFQGCILTSVWVLGHECGHHAFSEYNWLDDTIGLILHSSLLVPYFSFKISHRRHHSNIASLERDEVFVPRLKSAIPWYSKYLNNPPGRALTLVATLFIGWPLYLAFNVSGRYYDRFACHYDPYSPIYSDRERLQIYISDAMIFVAAYVLYKIAMAKGLAWLVCIYGVPLLIVNALVVTITSLQHTHVALPHYDSSEWDWLRGGLATVDRDYGVFNKIFHNATDTHVIHHLFSSMPHYHGVEATRAIKPILGDYYLFDDTPIHVALWREAKECLFVEPDEGDNNNGVFWYSNKF
What is the function of this protein?
Converts linoleic acid to alpha-eleostearic acid (18:3(9Z,11E,13E)) and alpha-linolenic acid to alpha-parinaric acid (18:4(9Z,11E,13E,15Z)).  Converts a single cis double bond at carbon 12 to two conjugated trans bonds at positions 11 and 13.  Can also act as a 12(E) desaturase when acting on the monounsaturated fatty acids oleate and palmitoleate, stereoselectively introducing a trans double bond.
What are the official names of this protein?
Bifunctional desaturase/conjugase FADX, Acyl-lipid (9+3)-(E)-desaturase, Delta(12) acyl-lipid conjugase (11E,13E-forming).
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ACPS_YERPY
Sequence: MAILGLGTDIVEISRIEAVVERTGERLARRILSPSEWQHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHSRAAELAVELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_ATRNU
Sequence: MAKVKIGINGFGRIGRLVARVILQSDDCELVAINDPFITTDYMTYMFKYDSVHGQWKHHELKVKDEKTLLFGERPVTVFGNRNPEEIPWGQTGADYVVESTGVFTDKDKAAAHLKGGAKKVIISAPSKDAPMFVVGVNEHEYKSELNIVSNASCTTNCLAPLAKVINDKFGIVEGLMTTVHSITATQKTVDGPSAKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMSFRVPTVDVSVVDLTVRLEKEATYEQIKAAIKEESEGKMKGILGYTEDDVVSTDFVGDNRSSIFDAKAGICLNGNFVKLVSWYDNEWGYSSRVVDLIRHMSKTTSKLDSVALACVDAVSTLILSSEC
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.