PharMolix/UniProtQA huggingface dataset:
Protein: GABD2_MYCTA
Sequence: MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQTDWAKRPVIERAAVIRRYRDLVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYARVCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVLKPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRLAEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTAYDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKARPDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWAGSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQTIATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  Although it has succinate semialdehyde dehydrogenase activity, is likely to act physiologically on a different aldehyde(s) (By similarity).
What are the official names of this protein?
Putative succinate-semialdehyde dehydrogenase [NADP(+)] 2, SSADH 2, SSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PURA_STRPJ
Sequence: MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRAHVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERLERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPENARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALKL1_DANRE
Sequence: MRAEKRWHILLSMILLLITSSQCMDSKEVKESERKTLLNLILQVIGEKPASRRVTSGLYSVSQDAKFSSRENTAHLPKPDNSRPIEIVPRDTSMKDKFIEHFTAGPVKFPSECRTHFHRIYHNTRDCSRPTYYKRCARLLTRLAMSPLCTQS
What is the function of this protein?
Cytokine that acts as a physiological ligand for receptor tyrosine kinases LTK and ALK (PubMed:29078341, PubMed:29317532).  Required for iridophore development in the adult eye by acting as a receptor for LTK (PubMed:29078341).
What are the official names of this protein?
ALK and LTK ligand 1, Augmentor beta, AUG-beta.
What is the protein family that this protein belongs to?
Belongs to the ALKAL family.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: NUPC_LACLM
Sequence: MNVVNTLQIIVANMLIYSTPLIFTSIGGVFSERGGIVNVGLEGIMTIGAFSSVVFNLTTAGMFGSMTPWLSILFGALIGALFSSLHAVATVNLRADHIVSGTVLNLMAPALGVFLLQVFYQQGQININEQIGYWNVPLLSNIPVIGKIFFTQTSLPGFLAIVVAILAWYVLFKTRFGLRLRSVGENPQAADTLGINVYAYRWAGVLLSGVLGGVGGAIYAQAISGNFSVSTIAGQGFISLAAMIFGKWNPIGAMLSSLLFGLFTSLAVVGGQIPGIKEIPSSFLQMAPYVFTIIVLALFLGKAIAPKADGVNYIKSK
What is the function of this protein?
Part of an ABC transporter complex involved in the uptake of all common nucleosides (PubMed:20595258).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Nucleoside ABC transporter permease protein NupC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CARB_MYCSS
Sequence: MPRRTDLRHVLVIGSGPILIGQAAEFDYSGTQACRVLRAEGLTVTLINSNPATIMTDPEYADYTYVEPITPDFVERVIAQQAERGNKIDALLATLGGQTALNTAVALSENGVLERYDVELIGADFDAIQRGEDRQRFKDIVTKVGGESAKSRVCFTMEEVRETVGELGLPVVVRPSFTMGGLGSGMAYSAEDVERMAGHGLASSPSANVLIEESIFGWKEYELELMRDRHDNVVVVCSIENFDPMGVHTGDSVTVAPAMTLTDREYQTMRDLGIAILREVGVATGGCNIQFAVNPKDGRLIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEILNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADATLTTTMKSVGEAMSLGRNFIEALGKVMRSLETGRAGFWTAPDPIATVDEVLENLRTPTDGRLYDIEFALRLGASVEQVAEASGVDPWFVDQIAGLVALRTELLDAPVLDGTLLRRAKNSGLSDRQIAALRPELAGEVGVRALRQRLGIHPVFKTVDTCAAEFEAKTPYHYSSYELDPAAESEVAPQAERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSEAGFETVMINCNPETVSTDYDTADRLYFEPLTFEDVLEIYYAESASGAGGPGVAGVIVQLGGQTPLGLAERLEQAGVPIVGTSPKAIDLAEDRGAFGEVLRTAGLPAPRFGLATTFDQARRIAADIGYPVLVRPSYVLGGRGMEIVYDEQTLEGYITRATQLSPEHPVLVDRFLEDAIEIDVDALCDGTEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIESVRRATEAIAHGVGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGASIAQLREEGVLAATGDGATTARNAPVAVKEAVLPFHRFRKADGAQIDSLLGPEMKSTGEVMGIDHDFGSAFAKSQTAAYGSLPSEGTVFVSVANRDKRSLVFPVKRLADLGFKVLATEGTAEMLRRNGIPCDEVRKHFEEPGAGRPARSAVEAIRAGDVAMVINTPYGNSGPRIDGYEIRSAAVSMNIPCITTVQGASAAVQGIEASLRGDIGVMSLQELHSELGN
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: NUSB_KLEP3
Sequence: MKPAARRRARECAVQALYSWQLSHNDIADVEYQFLAEQDVKDVDVLYFRELLSGVATNSAYLDGLMKPYLSRQLEELGQVEKAVLRIALFELSKRDDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPRKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MUTT_STRAM
Sequence: MLLYMSQPQEATSPPLHSVSVAGVVVREDGRLLAIRRADNGTWELPGGVLELDETPETGVAREVWEETGIRVEVDELTGVYKNTTRGIVALVFRCKPSGGVERTSSESTAVSWLTPDEVSERMAEVYAIRLLDALDGAGPHVRSHDGKHLIPAG
What are the official names of this protein?
MutT-like protein, ORF154.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: Y1427_CUTAK
Sequence: MGLSDKINSKSDEAVGAAKEKIGGLTDDSDLKSAGADQKASGKVAQKVEDVKDKANDLKHNVQAAADKLKG
What are the official names of this protein?
UPF0337 protein PPA1427.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: END4_HALSA
Sequence: MRVGAHVSIAGGVDNAVTNELDVGGNCGQIFTHSPQVWQDPNIGADEAAAFREGTAADLDGPWVIHSSYLVNLCTPKDDLRAKSIDSMQAEVDAAHTLGIPYVNVHLGAHTGAGVDDGLDNAASALDELDIPDDVTVLIESDAGSGTKLGGDFEHLHEVLTRSDQDLDVCIDTAHAFAAGYDLSTEAAVNDTLAAFDDVVGLDHLQYVHLNDSKHACGTNKDEHAHIGEGHIGEAGMRAFINHDAIADVPLVLETPHEDGRGFAWNIDRVRDLRA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RF2_CAMJR
Sequence: MDNYEFSELLKTLKNKVGNIASIIKPENIQTRLKEIEELENSPSFWSDVKQAGVIGKEKTKITNLLKNYENAFNALNDASELFDLANSENDTETLEALFNDAPKLEDTITSLEISMLLSGENDGKNAIVSIHPGAGGTESNDWASILYRMYLRFCEREGFKVETLDFQEGEEAGLKDVSFLVKGENAYGYLKAENGIHRLVRTSPFDSAGRRHTSFSSVMVSPELDDDIEIEIEEKDIRIDYYRASGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKATAFKMLKSRLYELELMKQQDSANTGEKSEIGWGHQIRSYVLFPYQQVKDNRSGEAFSQVDNILDGDIKKMIEGVLISLKAE
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE1_AQUAE
Sequence: MNLTIYLITDDKYFKDRDLFNTIEQALQGGVTAVQYRFENKTTRQMYEELVKLRELTRKYNADLVVNDRVDLALAVEADGVHIGKDDLPPEVVRKIVGDKMYIGYTANSLEEVKRAQELPVDYIGFGSIYHTSTKENYKLVGVEALKEAVKISQKPIVCIGGIMPYRVPEVVRAGCRNIAVSSGILGFADVKKAAESIKRAYQETLRMLMLMGKV
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase 1, TP synthase 1, TPS 1, Thiamine-phosphate pyrophosphorylase 1, TMP pyrophosphorylase 1, TMP-PPase 1.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: URE1_SYNS3
Sequence: MPYRISRQAYAETYGPTTGDRIRLADTELILEVEKDFTTYGDEVKFGGGKVIRDGMGQSQTSRAGGAVDTVITNALILDWWGIVKADIGLKDGRIVGIGKAGNPDIQEGVTIVIGPGTEAIAGEGHILTAGGIDTHIHFICPQQIETALASGVTTLMGGGTGPATGTNATTCTPGAFHIGRMLQAAEGLPVNLGFFGKGNASTPEALEEQVRAGACGLKLHEDWGTTPAAIDACLSVADQMDVQVCIHTDTLNEAGFVEDTIAAIKGRTIHTFHTEGAGGGHAPDIIKICGEANVLPSSTNPTRPYTRNTLEEHLDMLMVCHHLDPKIPEDVAFAESRIRRETIAAEDILHDLGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGALPEDSSRNDNHRLKRYIAKVTINPAIAHGISSQVGSVETGKLADLVLWKPGFFGIRPQLVVKGGSIVWAQMGDANASIPTPGPVHGRPMFAAFGKALAPSCLTFMSDAAMNDNIQSKLGLKRTCIAVENTREVGKSALKLNSALPNMSVDPQTYEVFADGELLTCEPAEVLPLAQRYLLL
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB1_STRA3
Sequence: MINNVVLVGRMTRDAELRYTPSNQAVATFSLAVNRNFKNQSGEREADFINCVIWRQQAENLANWAKKGALVGITGRIQTRNYENQQGQRVYVTEVVAESFQLLESRATREGGSPNSYNNGGYNNAPSNNSYSASSQQTPNFSRDESPFGNSNPMDISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: MACB_PSE14
Sequence: MQTPLIDLRAIRKSYGGGDSPLVNVLRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDREVAARAKRVIEISDGLVVSDTACDLSAPRSANPAALQAVDLRKRLSEGSGSRGAWKGELLDAVQAAWRVMWINRFRTALTLLGIVIGVASVVVMLAVGEGSKRQVMAQMSSFGSNIIYLNGKAPNPRAPKGIITLDEVAALGELPEVKMIMPVNGGQAGVRYGNVDHSSYVGGNDTHFPAIFNWPVVEGSYFSEADEQSAAAVAVIGYKVRQKLFGEHTDPIGQYILIENVPFQVVGVLEEKGATSGDLDSDNRIAIPYSAASIRLFGSQDPEYITIATRDANNVKHAEEAIRNLLQRLHNGKQDYELTNNAAMIQAEARTQNTLSLMLGSIAAISLLVGGIGVMNIMLMTVRERTREIGIRMATGARQSDILRQFLTEAVMLSVVGGLAGVVLALGMGAALLLSKVAVAFTVPAVAGAFACALVTGVIFGFMPARKAARLDPVAALTSE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXH_SALPK
Sequence: MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CARB_METBF
Sequence: MPKREDIKKVLLIGSGPITIGQAAEFDFSGSQACRSLKEEGIKVVLVNSNPATIMTDPEMADSVYIEPLDAKIVEKIIEKERPDGIIAGIGGQTGLNITSELAEKGVFEKYGVEILGTPVEAIKNTEDRELFKETMLRIGEKVPLSRAVNSLKEAEDVVDELGLPLIVRPAYTLGGAGGGIARTKEELLEITERGLRRSRINQVLIEESVLGWAEIEYEVMRDENDTCIVICNMENIDPMGVHTGESAVVAPSQTLSDAEHQMLRSASIKIIRALKIEGGCNIQYALKEGDYRVVEVNPRVSRSSALASKATGYPIARVTAKIAIGMKLDEIINNVTKSTPASFEPALDYVITKIPRWPFDKFTTADKTLTTAMKSTGEVMAIGRTIEESLLKAFKSLDIDNQLGNKHWDEPETKTLLKTPTSERLFVIFDALEKGMSVKEIFELSSINPFFISKIKRIVDMEKRIRAEELTPELLREAKKMGFPDTRLAELTGSTRQEISDLRHKAGILATFKMVDTCAAEFEAATPYYYSTYEDSCETNATTDKKKILILGAGPIRIGQGIEFDYCTVHAVTALREEGIETHIINNNPETVSTDFDTSDKLFFEPLTLEYVMNVIEREKPDGVLVQFGGQTSVNLAIPLKQELKRRTDLNTVILGTDPDDMDLAEDREKFYILMKELGVPQPEGGYATSHKEAIEVAKRIGFPVLVRPSYVLGGRAMEIVYDEIDLERYMKEAVRVSHEHPILIDDFLEAASEIDVDAVCDQKDVIIGAIMEHIEEAGVHSGDSACVIPPQSLSPEVLDQVRDYTRKIALALKVKGLINIQMAEKCGKVYVLEANPRSSRTIPFVSKSVGIPLAKIAAKVIAGHSLKSLGYTDEPKPKHVSIKEVLLPFDKLPGADPVLGPEMKSTGEVMGIDYDFGRAYYKAELAADNVLPLTGKVFLSIRNADKTELVDVAKKLQAAGLELMGTEGTVNYLARHGVFMDVVKKVHDGSPNVIDMMRRDEVDLIINTPTSKQSRRDGSRIRRAAVDFKVPYITTMQAAIAAAAAIETMKKGEELTIKSINEYHKEMEN
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: VL2_HPV58
Sequence: MRHKRSTRRKRASATQLYQTCKASGTCPPDVIPKVEGTTIADQILRYGSLGVFFGGLGIGTGSGTGGRTGYVPLGSTPPSEAIPLQPIRPPVTVDTVGPLDSSIVSLIEESSFIDAGAPAPSIPTPSGFDITTSADTTPAILNVSSIGESSIQTVSTHLNPSFTEPSVLRPPAPAEASGHLIFSSPTVSTHSYENIPMDTFVISTDSGNVTSSTPIPGSRPVARLGLYSRNTQQVKVVDPAFLTSPHRLVTYDNPAFEGFNPEDTLQFQHSDISPAPDPDFLDIVALHRPALTSRRGTVRYSRVGQKATLRTRSGKQIGAKVHYYQDLSPIQPVQEQVQQQQQFELQSLNTSVSPYSINDGLYDIYADDADTIHDFQSPLHSHTSFATTRTSNVSIPLNTGFDTPLVSLEPGPDIASSVTSMSSPFIPISPLTPFNTIIVDGADFMLHPSYFILRRRRKRFPYFFADVRVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: PSBI_CUSGR
Sequence: MFILKLFVYTVVIFFVSLFIFGFLSNDPRRNPEPEED
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: RNC_DESPS
Sequence: MGIDVKELIRRNRQKHAEFEKKINYKFIDLRLLQKALIHSSYAFEQAQAGKNNERLEFVGDAVLDLVVGNALYRRFPEMREGELTRLRAALVNEGHLATMARKINLGYFLCLGKGEDNSKGREKSSILSCAYEAVIGAIFQDGGYDAVAALVERFFLPVIDRRKEDLLLADAKSRLQEILQEKHNEGPSYRLDNEEGPSHKKRFTISVLFRDEVLGTGEAGSKKEAEQRGAALAIKKIESM
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB174_ARATH
Sequence: MSDLPLDLVEEILSRVSATSLKRLRSTCKQWNTLFKKRSFSQKHFHIAPKESMVLMLKEYRVCSMNINLNVSPPSVEFQGTLGIKDDSHSNLGQVEIVEVYHCDGLLLCATRDNRLVVWNPCLGETRWIQLKDECRRYSTFALGYENNKFCRRNYKILRYWGWFHDHIPDDGGRFRFEIYDFRSDSWKVLDDVPDDRFPPRDLIILVFRHLEIMVLWLYQLLEKNNSQCYKRLRHQRWRYL
What are the official names of this protein?
F-box protein At3g22350.
Protein: DNAA_LACP7
Sequence: MKSLIQEKWNEILEFLKIEYNVTEVSYKTWLLPLKVYDVKDNVIKLSVDDTKIGANSLDFIKNKYSQFLKTAIAEVINQDFEIEFVLLSQTKAEEKVQTQAPNKIKNESLSYLNPRYTFDTFVVGANNNLAHAASLAVAESPAEIYNPLFIYGGVGLGKTHLMHSIAHYILEQNPNSKVLYVTSEKFTNELIESIRNADTTPTEFREKYRNIDVLLIDDIQFIIGKERTQEEFFHTFNTLHESKKQIIISSDKPPKDILTLEERLRSRFEWGLTVDIQSPDYETRMAILKKKEELDCLTIDDEVMKYIASNIKSNIRELEGALTKIVALSRLKKKEVDVILAEEALKDLISPDNKKTVTLDLIIEVVSEHFTTSTSEIYSDNRSRNIAYPRQIAMYLCRKLTSLSLTDIGKMMGNRDHSTVLHGCNKVEKDIKKDPSFQNTIDVLIKKINPTP
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALE_YERPE
Sequence: MYVLVTGGSGYIGSHTCVQLIEAGYKPVILDNLCNSKSSVLARIHSLTGYTPELYAGDIRDRTLLDSIFAAHPIHAVIHFAGLKAVGESVNRPLEYYNNNVFGTLVLLEAMRAAQVKNLIFSSSATVYGDQPQIPYVESFPTGSPSSPYGRSKLMVEQILQDVQLADPQWNMTILRYFNPVGAHPSGLMGEDPQGIPNNLMPFIAQVAVGRRESLAIFGNGYPTPDGTGVRDYIHVVDLADGHVAAMKTLHGKPGVHIFNLGAGVGHSVLQVVAAFSKACGKPLAYHFAPRREGDLPAYWADATKAAEQLGWRVSRSLDEMAADTWHWQSKNPQGYPD
What is the function of this protein?
Involved in the metabolism of galactose.  Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: SRTD_BACSU
Sequence: MKKVIPLFIIAAGLVIAGYGGFKLIDTNTKTEQTLKEAKLAAKKPQEASGTKNSTDQAKNKASFKPETGQASGILEIPKINAELPIVEGTDADDLEKGVGHYKDSYYPDENGQIVLSGHRDTVFRRTGELEKGDQLRLLLSYGEFTYEIVKTKIVDKDDTSIITLQHEKEELILTTCYPFSYVGNAPKRYIIYGKRVT
What is the function of this protein?
Transpeptidase that anchors surface proteins to the cell wall (PubMed:21906378, PubMed:21800427, PubMed:22020651).  Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal.  Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (Probable).  This sortase recognizes a Leu-Pro-Asp-Thr-Ser/Ala (LPDTS/A) motif (PubMed:21906378, PubMed:22020651).  It has two substrates, YhcR and YfkN (PubMed:21906378, PubMed:21800427, PubMed:22020651).
What are the official names of this protein?
Sortase D.
What is the protein family that this protein belongs to?
Belongs to the bacterial sortase family. Class D subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Nonuniformly distributed around the cell periphery in the form of patches or short arcs.
Protein: VKT12_DENAN
Sequence: LQHRTFCKLPAEPGPCKASIPAFYYNWAAKKCQLFHYGGCKGNANRFSTIEKCRRACVG
What is the function of this protein?
DaE1 and DaE2 are serine protease inhibitors that inhibit voltage-gated potassium channels Kv1. 1/KCNA1 channels (IC(50)=300 nM).
What are the official names of this protein?
Kunitz-type serine protease inhibitor dendrotoxin DaE1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_SHEON
Sequence: MATLESRLADMLKVPVEALGFQLWGIEYVQAGKHSILRVFIDGENGINIEDCANVSRQVSAVLDVEDPISTEYTLEVSSPGVDRPLFTAEQYAAYVGEDVKLQLTMPVAGSRNLKGAITQVDGQMLSVNVNGKELVVALDNIRKGNIIAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_STRMK
Sequence: MTPVQRRRLAWVLLALLASGLATALVAMALERNIAYLYTPSEVLRGDVDAQSRFRLGGMVVKGSFNRPVGSLEARFEVTDGDAQLAVTTSRILPDMFAEGTAVVASGRLQDGTFVADEVLAKHDEKYVPKEVADKMGDAHRKHDVPVTAPEVR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: G1P_BPM13
Sequence: MAVYFVTGKLGSGKTLVSVGKIQDKIVAGCKIATNLDLRLQNLPQVGRFAKTPRVLRIPDKPSISDLLAIGRGNDSYDENKNGLLVLDECGTWFNTRSWNDKERQPIIDWFLHARKLGWDIIFLVQDLSIVDKQARSALAEHVVYCRRLDRITLPFVGTLYSLITGSKMPLPKLHVGVVKYGDSQLSPTVERWLYTGKNLYNAYDTKQAFSSNYDSGVYSYLTPYLSHGRYFKPLNLGQKMKLTKIYLKKFSRVLCLAIGFASAFTYSYITQPKPEVKKVVSQTYDFDKFTIDSSQRLNLSYRYVFKDSKGKLINSDDLQKQGYSLTYIDLCTVSIKKGNSNEIVKCN
What is the function of this protein?
Isoform G11P is also involved in phage assembly, probably playing a structural role in the formation of the phage assembly site.
What are the official names of this protein?
Gene 1 protein, G1P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G1P protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: KITH_STRPQ
Sequence: MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRIENGKPVYEGDQIQIGGNETYIPVCRKHYFNPEI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA81B_HUMAN
Sequence: MQLQFLGTLASSEKRKKSQRLFFKNIKSTKNKAGKASIMSSDTNVNKSASPTATAEEQPVEPDGPLPGSDNNQEKKVRLSPAKMSTKNSTDLVEYVDKSHAFLPIIPNTQRGQLEDRLNNQARTIAFLLEQAFRIKEDISACLQGTHGFRKEESLARKLLESHIQTITSIVKKLSQNIEILEDQIRARDQAATGTNFAVHEINIKHLQGVGDLRGRVARCDSSIVKLSGDIHLFRQEHRQIEKAIQEFVPALETLSKNLDMKVMQLLGKIETASSEQTSNLKMVQGDYRHEMNLLEFKFHSLSSNLYEEVENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEEKLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQNEYQSGFKSIHDSLSSLQQIQKTKMDLEKYKVQKDLKKLQRKIVELQEV
What are the official names of this protein?
Protein FAM81B.
What is the protein family that this protein belongs to?
Belongs to the FAM81 family.