PharMolix/UniProtQA huggingface dataset:
Protein: RIMP_HAHCH
Sequence: MARKDDLYQLLKPVVEGMGCDFWGMDYIAQGKRSLLRIYIDKESGVLVDDCEKVSRQISAILDVEDPIKGEYTLEVSSPGWDRPLFNVEQYKAYIGSIIEVRLQAPFNGRRKFKGLLAAVENDEIVLQVDAEEFIFPVETIDKANVVPQY
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB_DICNO
Sequence: MKVAKVFTTGRSQAVRIPKAFQFDTKEVIIQRFGNGILLIPKNSDWQGFLEALNEFEPDFKIEREPQIEQVREDFL
What are the official names of this protein?
Virulence-associated protein B.
What is the protein family that this protein belongs to?
Belongs to the VapB family.
Protein: PATR1_CAEBR
Sequence: MDEVKKYGKTLEEIEGELMFGKISFMLFLFHCIFSDDFPESLADSDEEHNIFDDEFDAANDETFGGGLDNIGENAEQVNCLVRAYHSLFFQTARLRLDDPVWHHPSSSDQVAPDASAIPFPTFGNGDSSDTFKSSFEAESPFLKKSIWGNGADSSFNIWGSDFGIAAVPPSSSFDLDYNSIAPNEAQQVSPLVQQKPSSQIPSMPSSALTVTCLLYHEFLNLISFKLEDFERMQLGDSTDTLTAALNDLQLGSTNAQSKIEQAPTTLQSAPGEPLKAQTLPKLPVSALSLEELEQKIIRESQTVNVANTQQTPQGSNRFAHPPPGFTANMKNAQHPAMGPPMGMPGMQMPPPPMGYQQMGAIMQELPRLPPLNPQYLPLVPIWLGAIVNNMQLPMGVPPIPPFLYQLLNHYRNPSLVHAMIVHSSIPPNSRPNGPQFSGPQVGPHSPGARGQQRRNSGMPSTRTIYDLALDSFAGYMSFKEREWLIRIQFVQCKGSGDPCIDDYYYVRWRESQIANGWTAHPKPESKQPLPASSESRKDYLERIRRMNYREMQKERLRDREKERQRERQERIDRGEERKPRQTLTDKFATSLGLPSKSSTHNPRHVLDMKAQVDSVDNQAKKLSDEERKNAVQKKLRTMLLRLEGALVLLMEAEELRRTSSSDKSQFKDLTSEEKEQEVEKRTSLIIDEFMGDDLPKLMQMSKGRAVLTRTLKVVGPRDQARIILSLMIAAGLVSKKMYGEIVLDILPVVHQKVSNLHPDQFKYLVGALNLDNIKRQLMDSNMFVRDVMLTLYLVSVKNNQNLLEWSKQTKFSSLKMPSSAPLGFWRKALSAVTDAEITEFAEDIKYSGVVDCHEVAKLIEQSL
What is the function of this protein?
RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs.  Acts as a scaffold protein that connects deadenylation and decapping machinery (By similarity).  Required for the recruitment of P-body components such as cgh-1 in somatic blastomeres (By similarity).  May play a role in recruiting the decapping enzyme dcap-1 to cytoplasmic puncta in the cell body of the posterior touch receptor neuron, PLM (By similarity).
What are the official names of this protein?
Protein PAT1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the PAT1 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: PDCD2_MOUSE
Sequence: MAAAAPGPVELGFAEEAPAWRLRSEQFPSKVGGRPAWLGLAELPGPGALACARCGRPLAFLLQVYAPLPGRDDAFHRSLFLFCCREPLCCAGLRVFRNQLPRNNAFYSYEPPSETEALGTECVCLQLKSGAHLCRVCGCLAPMTCSRCKQAHYCSKEHQTLDWRLGHKQACTQSDKIDHMVPDHNFLFPEFEIVTETEDEILPEVVEMEDYSEVTGSMGGIPEEELDSMAKHESKEDHIFQKFKSKIALEPEQILRYGRGIKPIWISGENIPQEKDIPDCPCGAKRIFEFQVMPQLLNHLKADRLGRSIDWGVLAVFTCAESCSLGSGYTEEFVWKQDVTDTP
What is the function of this protein?
May be a DNA-binding protein with a regulatory function.  May play an important role in cell death and/or in regulation of cell proliferation.
What are the official names of this protein?
Programmed cell death protein 2, Zinc finger protein Rp-8.
What are the subcellular locations of this protein?
Nucleus.
Protein: SY62_DIPOM
Sequence: MQAEMNQSAEVTMKTFFTMKTRETHPQAFVAPMATATMMPIDTGDNSTEAGVPGEGKNDVFEKLKEKFMNELQKIPLPPWALIAIAIVSGLLLLTCCLCICKKCCCKKKKNKKEKGKGKKNDINMKDVKGSGGNQDDDDAETGLTEGEDKEEEAKEEEKLGKIQFSLDYDFQANQLTVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVQKKTLNPTFNESFVFKVPYQELGGKTLMMAVYDFDRFSKHDCIGQVTVLMTKVDLGQQLEEWRDLESAEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPFEQIQKVQVCVTVLDYDKIGKNDAIGKIFVGSNASGTELRHWSDMLANPRRPIAQWHSLKPEEEVDVALGLKK
What is the function of this protein?
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse.  It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
What are the official names of this protein?
Synaptotagmin-B, Synaptic vesicle protein O-p65-B.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Synapse. Note=Synaptic vesicles in neurons.
Protein: MSP1_ASCSU
Sequence: MAQSVPPGDINTQPSQKIVFNAPYDDKHTYHIKITNAGGRRIGWAIKTTNMRRLSVDPPCGVLDPKEKVLMAVSCDTFNAATEDLNNDRITIEWTNTPDGAAKQFRREWFQGDGMVRRKNLPIEYNL
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein isoform alpha, Alpha-MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: HEM1_SHESA
Sequence: MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNGDEADIIEWLEEYHGLDHQDVAPCLYNYHGQAAVRHLMRVASGLDSLILGEPQILGQVKQAFVKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQSMCEEFNATAITLAQIPDFLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLHSIIEQNKASRKEAAEQAELITEEQSYLFMDWVRSLESVDSIREYRSQSMAIKDELVERALNKLAQGGDTEQVLIELANRLTNRLIHAPTQALTVASRQGDLNTLGQLRTALGLDKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HEM6_ECO57
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREGGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGKDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEGN_XENLA
Sequence: MDSAFLKLDAAEFLEIWQRFDADDNGYIEGKELDEFFCHLLKKLGTNAITADKVQGVKDRFMSAYDITADGRLQIQELANMILPEDENFLLLFRRETPLDNSVEFMRIWRKFDEDSSGFISAVELRNFLQDLFLQHKKHITGDKLDEYTDTMMKLFNRNKDGRLDLNDLAKILALQENFLLQFKMDASSQEERKSDFETIFAHYDVSKTGALEGPEVDGFVKDMMELVKPSISGVDLDKFRQILLNHCDVNKDGKIQKSELALCLGLKANP
What are the official names of this protein?
Secretagogin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_FRATT
Sequence: MARLKDYYQKELVAKLKTELGLDNIMEVPTIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: IFGG_PENRF
Sequence: MTIIPKHPSPTLFKPLALGKCQLQHRIVMSPTTRYRADEAAVPLPFVKEYYAQRASDPGALLITEATNICPNSVGEAHIPGIWSKTQCEAWREVVSQVHAKECYIFCQIYATGRSADPELLASRGFEQVSSSAVAAEPGCQPPRALDEEEIQKYISDYAQAARNAIEVGFDGVEIHGANGYLIDQFTQASCNQRTDEWGGDIPNRARFALQVTMAVINAIGPDRVGMKLSPWSQYSGMGIMGDLVPQFEYLILQLRQLGIAYLHLANSRWLDQMTTHPDPNHLTFVKVWGRSLPVILAGGYDATSAPEVIEMVYADYDNVAIGFGRYFTSTPDLPFRMKNGIALQKYDRSSFYTCLTKTGYLDYPYSPEYLCRSS
What is the function of this protein?
Chanoclavine-I aldehyde reductase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids (PubMed:28620689).  The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:28620689).  The second step is catalyzed by the methyltransferase ifgB that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptophan (PubMed:28620689).  The catalase ifgD and the FAD-dependent oxidoreductase ifgC then transform N-methyl-dimethylallyl-L-tryptophan to chanoclavine-I which is further oxidized by ifgE in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:28902217).  The chanoclavine-I aldehyde reductases ifgG and/or fgaOx3 reduce chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:28620689, PubMed:28902217).  The festuclavine dehydrogenases ifgF1 and/or ifgF2 then catalyze the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:28620689).  Hydrolysis of festuclavine by a yet undetermined cytochrome P450 monooxygenase (called ifgH) then leads to the formation of isofumigaclavine B which is in turn acetylated by ifgI to isofumigaclavine A (PubMed:28620689).  Penicillium roqueforti has interestingly at least two sets of genes for the consumption of chanoclavine-I aldehyde on three different loci, the OYEs ifgG/fgaOx3 and the festuclavine synthase homologs ifgF1/ifgF2 (PubMed:28620689, PubMed:28902217).  The reason for the duplication of these genes is unclear, probably to ensure the conversion of chanoclavine-I aldehyde by differential gene expression under various environmental conditions (PubMed:28902217).
What are the official names of this protein?
Chanoclavine-I aldehyde reductase ifgG, Isofumigaclavine biosynthesis cluster B protein G, Old yellow enzyme homolog ifgG, OYE ifgG.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: FBSB_NOSS1
Sequence: MENTLGLEIIEVVEQAAIASAKWMGKGEKNTADQVAVEAMRERMNKIYMRGRIVIGEGERDDAPMLYIGEEVGICTQPNADQLCNPDELVEIDIAVDPCEGTNLVAYGQPGSMAVLAISEKGGLFAAPDFYMKKLAAPPAAKGKVDINKSATENLKILSECLDRSIDELVVVVMKRDRHQGLIKEIRDAGARVQLISDGDVGAAISCGFAGTNVHALMGIGAAPEGVISAAAMRALGGHFQGQLIYDPEVVKTGLIGESKQANLDRLSSMGINDPDKVYDAHELASGENVLFAGCGITSGNLMQGVRFFHGGARTQSLVISSQSQTARFVDTIHMAGQPKTVQLH
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: PPIL4_NEUCR
Sequence: MSVLLETSAGDIVIDLLVDYAPKMCENFLKLCKVKYYNFSPIHSIQKSFSFQTGDPLGPLSSESDGGQSIWGLLSGDPSEKTFPALFHPKLKHLERGTVSMATVPHPSDPDTRLAGSQFIVTLGDNTDYLDGKAAIFGKVVEGFDVLEKINDAIVDERGHPLVDIRIKHTVILDDPYPDPAGMREPSASPPPSKAQLATVRITEGEELLDVEASEEAAAEAERRRREREAAAQALTLEMMGDLPFAEVKPPENVLFVCKLNPVTTDEDLELIFSRFGKILSCEVIRDQKTGDSLQYAFIEFEDKKSCEEAYSKMDSVLIDDRRIHVDFSQSVSKLSDVWRSETNSKRKSAARRGGGGWGGVDELEKWRKYRDEDVEWRNDDSYQMVHGVEDLKGRHDGDKPPVRDSRPDVGGGRDRSTSRRSRSPRRDRDRRDDRDNRRGPRDADRRRDDRDLDRRDRRGDRSRDRYRDRDYNDRDHRRGRDRDNRGRDDYRRR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 4, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y480_RICFE
Sequence: MFKRSLFILLLLAASLVKAEIIEVDSLNKIKQDFKENYNKNYVPQDLLVVTVLDEFLFKSLVPIGEQIDKDIYLTLTPLLRNINKNSKAIYIDQLILTNDSYKKELQESDFPNFVNEMSNSKIPIIAVNDGFTGNFNNIPKFEIWFADYLKKNFNIDFSNSFPNNNYIIFNNLDSFANTYPVFYKGILTSNNISKAEMMLNFLIQVGFMPKAFIIISNNIELLKSMEFQLNSYSSNILFIGYHYNNKNTPENKDAAYYTKIINDLISQINKIKRNNPPLKTNKIKDKNPYDKNQ
What are the official names of this protein?
Uncharacterized protein RF_0480.
Protein: Y1771_PASMU
Sequence: MMENQEFLSLDEAVLLSNKFNLNFSKEDILYLSSLDHFKAYNNIQYVYMGDVQKPVYKIHGLKGFFKTRLETKSRLLLQELDIIRTNDSYVIDKKKEQGFSRDIWTIKERNNLKSVLYLHLSNRYDDLYFIDYGFASVTLPIYEERVKKHDIVKGMVESTMLSNIAIRNKPQNAKLFVSFLSKSLTNHYVPNSSFDIFEFNIAGIIDYPFSLEPYILSYKEKEDDDLLELYNEYNFDEIFYFKHTDLLEYFQKIIDKEEKIQKSYQYQTELITELQGRIAELEKENQSLKENVKEPETSKPIRPDEKETLLKLIYALAMGRTDKDFSASAYFNKKGVLKVSTMINEIVADLEQVGIMNFSDGTLRKRLSEILQMGELKAD
What are the official names of this protein?
Uncharacterized protein PM1771.
Protein: RL3_STRCO
Sequence: MTKQIKGILGEKLGMTQVWDENNRVVPVTVVKAGPNVVTQVRTNDVDGYESVQIAFGEIDPRKVNKPLKGHFAKADVTPRRHLVEIRTAAASEYTLGQEITAEAFESGVKVDVTAKSKGKGFAGVMKRHNFKGGKASHGAHRVHRMPGSIGGCATPGRVFKGMRMAGRMGNERVTTQNLTVHAVDAEKGLLLIKGAVPGPNGGLVLVRTAAKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YBIS_ECO57
Sequence: MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVITIPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIVINSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAEYRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDIKFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKSVQTVTGQPDVDQVVLDEAIKNRSGMPVRLN
What is the function of this protein?
Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp.
What are the official names of this protein?
Probable L,D-transpeptidase YbiS.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TBP_ARCFU
Sequence: MQDYKIKIENVVASTQIGENIDLNKISREIKDSEYKPKQFPGLVLRTKEPKAAALVFRSGKVVCTGSKSVEDARRAVKQIVKMLKEIGISVIDEPEVKVQNIVASADLGVDLNLNAIAIGLGLENIEYEPEQFPGLVYRLDNPRVVVLIFGSGKMVVTGGKSPEDARKAVERISEELRTLGLM
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: DAPB_METLZ
Sequence: MIKVIICGALGRMGTMIANMVIENPELEFVGGVDIRDGTVLGKPVVPSEKLAAFIDEVKPDVMIDFTVAAATMINAKIAAKKGVALVIGTTGFTPEQDAELLDAIKNVPVVKTTNFSVGVNIFWELVRDAASRLGDYDIEVIEAHHRYKKDAPSGTAKTILKVIQEEVGKREEMYGREGMTERKNEIGVHVIRGGDVVGDHTVQFHQNYETIELTHRAYDRAVFARGAIRAAAWVPKAKPGVYTMKEVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKG2D_MACFA
Sequence: MGWIRGRRPRHNLEMSEFHNYKLGLAKSDFSTRCQKQRCPVIKSKCRENASPLFFCCFIAVAMGIRFIIMVTIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFNESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLTIIEMQKGDCALYASSFKGYIENCSIPNTYICMQRTV
What is the function of this protein?
Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells.  Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity.  Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation.  Stimulates perforin-mediated elimination of ligand-expressing tumor cells.  Signaling involves calcium influx, culminating in the expression of TNF-alpha.  Participates in NK cell-mediated bone marrow graft rejection.  May play a regulatory role in differentiation and survival of NK cells.  Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins (By similarity).
What are the official names of this protein?
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Colocalized with HCST on the cell surface.
Protein: URK_STAEQ
Sequence: MNQTTIIGIAGGSGSGKTTVTNAIMKNLEGHSVALLAQDYYYKDQSHLTFEERLETNYDHPFAFDNDLLIHNLKDLRNGKPVEVPTYDYSQHTRSKETIAFDPKDVIIVEGIFALENNTLRDMMDVKIYVDTDADLRILRRLTRDTKERGRTMESVINQYLNVVRPMHEQFIEPTKKHADIIIPEGGSNKVAIDIMTTKIQSLVSKK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_STAAN
Sequence: MAKVLYITAHPFNELVSNSMAAGKAFIETYQQQHPDDEVKHIDLFETYIPVIDKDVLTGWGKMSNGETLTDDEQMKVSRLSDILEEFLSADKYVFVTPMWNLSFPPVVKAYIDAISIAGKTFKYSAEGPQGLLTDKKVLHIQSRGGYYTEGPAADFEMGDRYLRTIMTFLGVPSYETIIIEGHNAEPHKTEEIKATSINNAEKLATTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: BRX1_DROME
Sequence: MGRKFQNKKKKAAPQLEIVPLDENPPLPPQRSSDDVVPKKARKEKWVNKQRVLVFSARGISHRDRHLMKDIKTLMPHHRPESKMERSKTLSVVNEMCEMKHCNKAMLFEGRRKRDLYMWISNTSGSTGPSAKFLIENIHTMAELKMTGNCLRGSRPLLSFDSKFDELPHLKLLKELFVQTYSVPNHHPKSQPFVDHVFTFTYLDKRIWFRNFQILSEDGGLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQRQVLKKAAKDKYVNRVEQKVKHEATRPIRAYDGMDNDELFEDDDPVETAKILAAIAKKKKEEAAKQTPKSALTKKIKEKQLQAVKDVIERKKARTIKRVKKV
What is the function of this protein?
Required for biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BRX1 homolog, Brix domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the BRX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LPXA_PSEU2
Sequence: MSLIDPRAIIDPTAVLADNVEVGPWSIIGPGVEIGEGTVVGPHVVLKGPTRIGKHNRIYQFSSVGEDTPDLKYKGEETRLVIGDHNVIREGVTIHRGTVQDRAETTLGDHNLIMAYAHIGHDSVIGNHVILVNNTALAGHVHVDDWAILSGFTLVHQFCHIGAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSEEAIHALRRAYKTVYRQGLTIGQALADLAEPAAQFPEVAVFLQSIQTSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_THEAB
Sequence: MSRIANKPIVIPNGVEVKVEGNVLKVKGPLGELKQDFLPYVKVEINGNEMNVKPNVDYMKRRSDLKKMKMFTGTYWRLFNNMVIGVTKGFKKELEIVGIGYRAQLQGKKLVMNLGYAHPVEMEIPSDVKVEVPSPNKIIVSGIDKQRVGQVAADIRKWREPNVYSGKGIRYVGEVVRLKEGKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS8_AERS4
Sequence: MSMQDPIADMLTRIRNGQAASKVAVSMPSSKLKVAIAKVLKEEGYIAGYSVAGDVKPELEIELKYFQGKPVVELIQRVSRPGLRIYKRTTDLPKVMGGLGVAIVSTSKGVMTDRAARKASMGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GATC_ACET2
Sequence: MKVDKETIEYVANLARLRLSEKEKEKLALDLESIISYVDKLNELDTSKIIPTDHVIPIKNVFRDDEVRDSYPKDKMLMNAPEKEDGCFKVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: LIPA_PSYIN
Sequence: MSNKPSQLTAGKKLRDADKMSHIPIKVVPSNKSTLLKKPSWMKIKLSSDNTRVNEIKAALRKNNLHSVCEEASCPNLNECFNHGTATFMILGDICTRRCPFCDVGHGKPLAVDANEPKKLAETIKDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRLLNPEIKIEILVPDFKGRMDKALACFEQDLPDVFNHNLETAPHLYKQVRPGADYKWSLKLLQKFKEKHPHIPTKSGLMVGLGETNEDIEQVLTDLRAHDVNMLTLGQYLQPSLDHLAVQRFVPPSEFDELGVKAKALGFDQAACGPLVRSSYHADLQASGQEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DERL2_CAEEL
Sequence: MNGVVAALEEMPPVTRFYTGACVLLTTAVHLEFVTPFHLYFNWELIIRKYQFWRLITSFCFFGSFGFSFLFNMIFTYRYCMMLEEGSFRGRRADFVYMFLFGAVLMILSGIFVQILFLGQAFTIMLVYIWSRRNPMIQMNFFGVLTFTAPYLPWVLLLFSLLLGNNAVVDFMGIACGHIYFFLEDVFPFQEHGKRFLKTPQWLVYLFDERRPEPLPEDERPGGFEWGDEQPEQEQHD
What is the function of this protein?
May be required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.  Its precise function remains unclear, but its ability to complement der1 mutations in C. cerevisiae, suggests a similar function in the degradation of ER misfolded proteins.
What are the official names of this protein?
Derlin-2, DER1-like protein 2, cDerlin-2.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.