PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_CYAM1
Sequence: MKLLNQMELLLSTCKNRYVLTREVAEYAKKTPSPNAVILAIWLMARKTK
What is the function of this protein?
May be involved in RNA polymerase activity.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit omega, PEP, Plastid-encoded RNA polymerase omega subunit, RNA polymerase omega subunit.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDHI_ORYSA
Sequence: MFPMVTGFMSYGQQTIRAARYIGQSFIITLSHTNRLPITIHYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPLVDWRFEKDIKRKQLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALSRLPISIMGDYTIQTIRNSTQSKIDEEKSWNSRTITDY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: AROC_BACFN
Sequence: MFNSFGNIFRLTSFGESHGKGIGGVIDGFPAGIVIDEEFVQQELSRRRPGQSVITTSRKEADKVEFLSGIFEGKSTGCPIGFIVWNENQHSNDYNNLEKVYRPSHADYTYTVKYGIRDHRGGGRSSARETISRVVGGALAKLALRQLGIHITAYTSQVGPIKLEGNYTDYDLDLIETNPVRCPDPEKAKEMQDLIYKIKGEGDTIGGVLTCVIKGCPIGLGQPVYGKLHAALGNAMLSINAAKAFEYGDGFKGLKQKGSEQNDVFYNNNGRIETRTNHSGGIQGGISNGQDIFFRVAFKPVATVLMEQETVNIDGIDTTLKARGRHDPCVLPRAVPIVEAMAAMTILDYYLLDRMTQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SEPF_STRU0
Sequence: MAFKDAINKMVSYFDTDEVNEVEEEVTAAKMEEPVVQEPKQRPIPSQQTSRQSQNPAMNRPTVARSQQTESDSLPTYPNRQESIDRRSSGRESVTASTARRETYQAQTTVQEGKTTIALKYPKKYEDAQEIVDLLIGNECVLIDFQFMLDAQARRCLDFIDGASKVLYGTLQKVGSSMYLLTPSNVSVNIEDMNIPNHNQDFGYDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PDRP_STAA1
Sequence: MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIESFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASVEEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPLSQYLAHKSYKVMNVPIVPEVTPPDGLYDIDPKKCIALKISEEKLNRIRKERLKQLGLGDTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: DUS_STAAS
Sequence: MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: LIPA_BUCA5
Sequence: MKKNKDVLLKNKILKKLNIINIKNLDNIKEKLKKPDWIKIKIPVNTSRIYQIKNALRKNNLYSVCEEAHCPNLSECFNNGTATFMILGSICTRNCPFCAVFHGRPNPVNVEEPQKLSDTIFDMGINYVVITSVVRDDLYDGGAEHFVNCIKAIKNKNQVKIEILVPDFRGRIELILNIFNNALPDIFNHNIENVPRLYKKIRPGANYQRSLLLLESFKKKYCSVLTKSGLMLGLGEKDVEIIQVMKDLYSSGVTLLTVGQYLQPSIHHLPVKRYIPLSEFENIKKEALSIGFTNAFCGPFVRSSYHASFQSHLPIKNNDINNI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSB_SHEPC
Sequence: MPKQDSLWLKSLRWIQKHLVHTIVVPQDPFADLNLDTSRPLAYVMKTESLSDIAALSEVTEKLGLPSPYEPLVVNGVVAPRVVCLQGRKPLFGERAGNEPFLECFMRLLAVHKERPELDIQLVPVSLYWGRTPGKEDDTMKAAVLERENPTWLRKCFMILFLGRHNFVQFSNAVSLRYMADEHGTDMGIAHKLARVARVHFRRQRKVMTGPLLPNRQALFDSLLKSESLRKAIQEEAVSKKISETQARETAIEYLDEIAANYSDSLVRIAERFLTWLWNKLYSGINIKGAEHIRQLHHDGHEIVYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPLFRRGGAFFIRRSFNGNKLYTAVFREYLDQLFAKGYSVEYFSEGGRSRTGRLLAPKTGMIAMTMNSVLRGIERPVTLVPVYLGYDHVMEVATYHKELSGKKKQKESVWQVFGAIRKLGNFGQGYVNFGEPITLQTFLNEMAPNWRAELADDPEQKPTWLTPAVNVLANRVMTRINDAAAASSVTLTSLALLASEQNALERCLLERQLDLYLTLLKRVPYTSFTSVAEGDGKHLVQQGINLNKFSVSSDPLGEIVSIDANQAISMTYYRNNIIHLFIIPSLIASCLTHNEQSQRQQIVAIVNDFYPLLKAELFMGIKDIPSYVNQVLDLFIEQGLITESDNLSVVTEHSSQLVLLSGSVSETLQRYAIIFNLLAHRPKMERSELESESHLLAQRLGALHGITAPEFYDKKLYGTLSVKLKELGYLSDKDDKSDVKRIRDQANSLLRASVRQTIVASVTAEHIS
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TBPL1_XENLA
Sequence: MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGLNVIYKREVSKVLMKLRKPRITATIWSSGKIICTGATSEEEAKVGARRLARSLQKLGFQVKFTEFKVVNVLAVCTMPFEIRLNEFTKQNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPDVKSVASAIEQIYPFVFESRKTIL
What is the function of this protein?
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes.  Seems to also mediate the transcription of NF1.  Does not bind the TATA box (By similarity).  Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis.  Particularly regulates genes that have a role in catabolism.
What are the official names of this protein?
TATA box-binding protein-like 1, TBP-like 1, TATA box-binding protein-related factor 2, TBP-related factor 2, TBP-like factor, xlTLF.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVB_THERP
Sequence: MNEPRIVAPQPTTSEQYFEETLRPRRLAEYIGQDRVKESLAIAIRAAQERGEPLDHLLFYGPPGLGKTTLAGIIAAEMGVNLRITSGPAIERPGDLVSILTNLRPGDVLFIDEIHRLNRLVEEILYPAMEDFAVDLVIGKGPAARSVRIALPRFTLVGATTRLALLTSPLRDRFGATYRLDFYDTAALRAIVERAARILQVPITSDGAEEIARRGRGTPRIAIRLLKRVRDYAQVIGDGTITRELARLALDQLAVDELGLDEVDRLILRTLVEKFDGGPVGIQTLAAATSEEPDTIESVYEPYLLQLGFLQRTPRGRIATRRAYEHLGLTYPENRLQLEIPFEHAASERSSDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LPTE_YERPB
Sequence: MRHRILTLLLGLAVLVTAGCGFNLRGTTQVPTELQKLLLESSDPYGPLARSIRQQLRLNNVTIVDDAMRKDIPTLRIIGSSESQETVSIFRNGVAAENQLVLHVQAQVLIPGHDIYPLQVNVFRTFFDNPLTALAKEAEAEVLRQEMREQAAQQLVRQLLTVHAAEVKNTQKNGDKPVSDANAAQGSTPTAVNETTLGEPAVSTSAK
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CUL1_DICDI
Sequence: MSMMTSTPTKRSVKLDDIWPELEEGIYKIITDLNKGFPKQKWIALYTHVYDYCAASQSKSSAKVGMPKQQASGANYVGEDLYNRLNLFLKKHMSQLLKLTETKMDEPLLNYYYTEWDRYTSAMKYINNIFQYMNRYWIKREIDDGKKEVYEIFILSLVIWRDCLFTPLKQRLTNSLLDIIESERNGYQINTHLIKGVINGYVSLGLNREKPKETILQVYKSGFEELFLTATENYYTNESAKFISENSVADYMKKVETRLNEEVKRVQQYLHQNTESELIAKCEKVLIEKHVEVIWNEFQTLLEKDKIPDLTRMYSLLSRIPRGLEPLRTTLEKHVQNVGLQAVSSIATNGVIEPKVYIETLLKVFKKYNELVTGAFRSDTGFVASLDKACRRFINENAVTIAAKSSSKSPELLARFTDFLLKKSPNNPEESEMEQLLNDVMIVFKYIEDKDVFQDFYSKMLAKRLIHGTSTSEDLEGTMIGKLKSTCGYEYTSKLQRMFTDMSLSRELLDRFNNHIEQVERSSLNIDFSVLVLATGSWPLQPPSTNFSIPKELQACEQLFQKFYQNQHSGRKLNWLHHLSKGELKTKYLQTSKSGYTLQCSTYQIGVLLQFNQYETLTSEEIQESTQLIDSVLKGTLTSLAKSKILLADPPLDDEEIAKTTKFSLNKQFKNKKTKIFINVPVLTQVKEEIDSIHKTVEEDRKLQIQAAIVRIMKMRKQLAHSGLMTEVISQLQTRFNPKVNIIKKCIDILIEKEYLMRVEGKKDHYSYVA
What is the function of this protein?
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity).  Required at several stages during development.  CulA and fbxA regulate multicellular development by targeting regA for degradation via a pathway that requires erkB function, leading to an increase in cAMP and PKA activity.
What are the official names of this protein?
Cullin-1, CUL-1, Cullin-A.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: DCD_COXBU
Sequence: MPIKSDKWIRRMAESHQLIYPFEPKQVRETPSGKVISYGTSSYGYDVRCADEFKIFTNINASIVDPKNFDPNGFIDLKANVCIIPPNSFVLARTVEYFKIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLESDEVCDISYKDRGGKYQGQKGVTLPVA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ECCD3_MYCTU
Sequence: MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAVQRLVVPSAQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRLKPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVASALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGVAAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIGCGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTATGRYVAAFGAVLVLAVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVGLFAWVLNR
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
What are the official names of this protein?
ESX-3 secretion system protein EccD3, ESX conserved component D3, Type VII secretion system protein EccD3, T7SS protein EccD3.
What is the protein family that this protein belongs to?
Belongs to the EccD/Snm4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABH_LISM4
Sequence: MNAGILGVGKYVPEKIVTNFDLEKIMDTSDEWIRTRTGIEERRIARDDEYTHDLAYEAAKVAIKNAGLTPDDIDLFIVATVTQEATFPSVANIIQDRLGAKNAAGMDVEAACAGFTFGVVTAAQFIKTGAYKNIVVVGADKLSKITNWDDRTTAVLFGDGAGAVVMGPVSDDHGLLSFDLGSDGSGGKYLNLDENKKIYMNGREVFRFAVRQMGEASLRVLERAGLEKEDLDLLIPHQANIRIMEASRERLNLPEEKLMKTVHKYGNTSSSSIALALVDAVEEGRIKDNDNVLLVGFGGGLTWGALIIRWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities (PubMed:19863661).  Can use branched-chain acyl-CoAs, with a preference for 2-methylbutanoyl-CoA, the precursor of odd-numbered anteiso fatty acids, at 30 degrees Celsius, which is further increased at a low temperature (PubMed:19863661).  Shows weak activity with acetyl-CoA (PubMed:19863661).
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III, Branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
Protein: UVRB_BACCZ
Sequence: MKRQFEIVSAYSPQGDQPVAIEKLVEGINSGKKKQVLLGATGTGKTFTISNVIKEVQKPTLVMAHNKTLAGQLYSELKDFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVSLRVGMEKDRNQLLRELVDVQYGRNDIDFKRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVNALTGEVLAERDHVAIFPASHFVTREEKMKVAIENIEKELEERLKELNDNGKLLEAQRIEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGATPYTLLDYFPEDFLIVMDESHVSVPQVRAMYNGDQARKQVLVDHGFRLPSALDNRPLTFDEFEEKTNQVIYVSATPGPYELEQSPEVIEQIIRPTGLLDPPIDIRPIEGQIDDLLGEIQDRIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEVKTLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNENGRVIMYADRITRSMGIAIEETQRRRSIQEAYNEEYGITPKTIQKGVRDVIRATTAAEEPETYEATPAKKMTKKEREKTIAKMEAEMKEAAKALDFERAAELRDLLLELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2BD_PSEAU
Sequence: NILQFRKMIQCANKGSRAAWHYLDYGCYCGPGGRGTPVDELDRCCKIHDDCYIEAGKDGCYPKLTWYSWDCTGDAPTCNPKSKCKDFVCACDAAAAKCFAKAPYNKANWNIDTKTRCK
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PA-13, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOCD_ESCF3
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SUCC_FRAT1
Sequence: MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGVFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQENAKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAILINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ARLY_DESVM
Sequence: MAEKKMWGGRFRQATAALVEEYTQSVSFDRALYAQDIAGSKAHARMLAKQGVLTADEAARIVEGLDMVLAEIEGGTFVWRRELEDVHMNIESRLTELVGDVGKKLHTGRSRNDQVALDFRLFVSDRIRAWRGLARDLVAVLAERAGEHANTLLPGCTHMQPAQPVSLGHHLLAYAWMLRRDAERLADCDRRTRVCPLGAAALAGTTYPLDPAYVAEQLDMYGTFRNSMDAVSDRDFVLESLFCGATIMAHLSRLCEEIIIWANPAFGFVRLPDAYATGSSIMPQKKNPDVAEIMRGKTGRVYGALTAMLTTVKGLPMTYNRDMQEDKEPFLDCDRTVSASLEIMAGMLRELGFNEGRMRAALRAGFLNATELADYLVGKGIPFREAHHLTGAAVALAEERAITLEELPLADLQAICDRIGDDVYAVLDPAAAVARREMPGGTGPASVAAQLAELSGWLEE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_HAEIE
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKHYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALQALNGVAEWEEKILELANHLDTYIPEPERAIDQPFLLPIEDVFSISGRGTVVTGRVERGIIRTGDEVEIVGIKDTAKTTVTGVEMFRKLLDEGRAGENIGALLRGTKREEIERGQVLAKPGSITPHTDFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMTVSLIHPIAMDQGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTA_SHEON
Sequence: MQQLNENKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSASTVLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKAHRGESL
What is the function of this protein?
Antitoxin component of a type VII toxin-antitoxin (TA) system.  Upon overexpression in situ or in E. coli neutralizes the effect of cognate toxin HepT (PubMed:26112399, PubMed:29555683, PubMed:33045733).  Neutralization is mostly due to tri-AMPylation of toxin by this enzyme.  Successively tri-AMPylates HepT on 'Tyr-104' (PubMed:33045733).  Binds its own promoter, probably repressing its expression.  The TA system confers plasmid stability in E. coli (PubMed:26112399).
What are the official names of this protein?
Protein adenylyltransferase MntA, Antitoxin MntA.
What is the protein family that this protein belongs to?
Belongs to the MntA antitoxin family.
Protein: VATB_CHLTR
Sequence: MQTIYTKITDIKGNLITVEAEGASLGELVQIERADGRSSYASVLRFDARKVTLQVFGGTSGLSTGDKVIFLGRPMEVIYGDSLLGRRFNGTGKPIDREDECFGEPIPITTPSFNPVCRIVPREMVRTNIPMIDMFNCLVKSQKIPIFSSSGENHNALLMRIAAQTDADIVIIGGMGLTFVDYNFFVKESQRLGFADKCVMFIHKAVDAPVECVLIPDMALACAERFALEQKKNVLVLLTDMTAFADALKEMAITMDQIPANRGYPGSLYSDLAVRYEKAVDIAQGGSITLISVTTMPGDDITHPVPDNTGFITEGQFYLKDNRIDPFGSLSRLKQLVIGKKTREDHGDLANALIRLYADSRKSAERMSMGFKLSNWDKKLLAFSELFEARLMSLEVNIPLEEALDIGWKILSQSFHSEEVGIKEQLIQKYWPKACLHK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.