PharMolix/UniProtQA huggingface dataset:
Protein: PROA_SYNR3
Sequence: MHGSPPAQALNQAVPDPSPELLARASSLRRHAIDLAQCSDQQRQEALRAMADALEQQREAILLANQDDLQAAEQEQLAPALLSRLKLDRTKLDGAIAGIRQLAQLPDPLAQRQLHRALDEGLVLERISVPLGVVGVIFEARPDAVMQIAALAIRSGNGAILKGGREANRSCSAILAALQQGLARSAVHPDVLTLLTSREESLALLKLDGLVDLIIPRGSNALVQFIQDNTRIPVLGHADGICHLYVDRQVDLDQAVAVAVDSKAQYPAACNAIETLLLHKEIAPAFLAAALPAFAQAGVELRGDGAAMALGVSQSASDDDWATEYLDLVLSIRVVDSMDEALEHIARYSSRHTEVICTTNTETAERFLARVDSAGVYQNCSSRFADGFRYGFGAEVGISTQTLPPRGPVGLEGLVTYRYRLRGDGHIAADYASGARQFTHQNLPL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SHEB9
Sequence: MSLADSVLAINNDLPIRTDSPVHSGKVRSVYWLTDADSRRLITTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKDQKLPELLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEQLADIDLYEKLLKDGFKVISAALAKLDQVFVDTKFEFGYVTDKDGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDVLLNKDRMPEREALARDNDLPLEAMMQVSRTYTGVAEKVTGAPIPLPANPKADIIKILREEYDLIV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PRPS2_MACFA
Sequence: MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
What is the function of this protein?
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 2, Phosphoribosyl pyrophosphate synthase II, PRS-II.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: PUR9_MOOTA
Sequence: MSKRALISVSDKTGLVELARGLVELGWELLSTGGTARTLIAAGLPVTEVAAVTGFPEILDGRVKTLHPKIHGGILARPTPEHLAQLQEQGIQPIDLVVVNLYPFRETIARPGVTPAEAIENIDIGGPAMVRAAAKNHERVGIVVDPASYNEVLTELREKGSLSPETRRRLAAAAFAHTAAYDAAIAAYFQRLMRNEEPFPASFVLSGEKVQDLRYGENPHQGAAFYRLPAPPPGTLAGARQLQGKELSYNNLMDLDAAWNLACDFKEPVVAIIKHTNPCGVARASTPAAAYRLAYAADPVSAFGGIVACNRPVDGEMAGAMTEIFLEAVIAPSFTPEAMAILKSKSNLRLLAAGERAGCRTREYQIRPVSGGFLVQEPDYHVLEPESLKVVTARKPEAKEMADLLFAWQVVKHVKSNAIVVARDGVTLGIGAGQMNRVGAARIALEQAGARAKGAVLASDAFFPFGDTVELAAGAGITAIIQPGGSIRDEESIRAADAAGIAMVFTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: COAD_BUCAI
Sequence: MNKTAIYPGTFDPITYGHLDIITRATKIFDSITIAISNNFTKKPIFNLKERIELTRKVTLHLKNVKKILGFNDLLANLAKKEKANILIRGVRTIFDFDYEIKLAAINKQIYPDLDSIFLLSSKEVSFISSSFVKEIAKYKGDIKPYLPKEAHSALLRKLNNDSIK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPA_STAAE
Sequence: MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFIGTTVFGGLSLALGAALLAGRRREL
What is the function of this protein?
Plays a role in the inhibition of the host innate and adaptive immune responses.  Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (By similarity).  In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region.  In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production (PubMed:28031339).  Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin (PubMed:22792377).  Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (PubMed:15247912, PubMed:16709567).
What are the official names of this protein?
Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein SpA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Secreted. Note=Released from the cell wall in a glycan-free form by LytM; released early in log growth, almost no release occurs after 3 hours growth (PubMed:24434550). Anchored to the cell wall by sortase A (By similarity).
Protein: PYRG_LIGS1
Sequence: MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGTETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLKKERRGDYLGATVQVIPHITNMIKEKIMRAGTITDADVVITEVGGTVGDIESLPFLEALRQMKSEVGSENVVYIHTTLVPYLHAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEKPISQSMRNKIANFCDVEPEAVIESMDVDTLYSIPLNLQAQNMDEIVCKKLHLDTPAADMTEWAALRDKVKNLSGEVKIALVGKYVQLPDAYISVNEALKHAGYTIDANVKIDYFDSEKLTAENVADELKGYDGVIVPGGFGDRGLEGMIQAIRYARENDVPYLGICLGMQMACIEFARDVAGIEDATTGEVNPKAANKIIDLMADQEDVENMGGTQRLGLYPCKLKAGSVASAAYGNQDVIQERHRHRYEFNNKYRDELAAKGLVFSGTSPDNRLVEVVEIPENKFFVAAQYHPEFLSRPQRPEGLFQAFINASAGK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TVP18_ASPFU
Sequence: MTLAEEFRSRNFSIYGQWTGVLCIILCIALGIANIFSFAVLRIIFSVLCLISGLILIFIEVPFLLRICPTSSKFDAFIRRFTTNWMRAAMYGVMSVVQWLSLLPGSGASSLIVAAVFLLIASIFYALAGLKSQEFVGSKTLGGQGLVQMIV
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein tvp18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: YXEE_BACSU
Sequence: MNPYQYYSPQLPQQEPYYSHYEYNPYPQQDVYDPYQMDRQPALERRIAALERQNEQQSRELTRLTNEDRRQNREIARIAEQVNQLSQAVERHTRRLNRLNQRLRTVENRLNIPFTAGEGGF
What are the official names of this protein?
Uncharacterized protein YxeE.
Protein: PRE_BACSP
Sequence: MSFAVVRMQKMKSYDLKGIQFHNQRERESKTNPDIDKERSHENYDLVNDEPIDYNERVKEIIESQKVGTRKTRKDAVLVNELIVTSDRHFFERLDPDEQKRFFEESYKLFADRYGKQNIAYATVHVDEKTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQDKFPEHMQKLGFDLQRGEKGSDREHIETSKFKKQTLEKEIDLLENELKNKKSELAILSEEVSGEFKIPVKREKKSVEVPTGKRNLLGIEQKKTVMKSTGNVILKDEVFQDLKQKVKAGAVLQTRVDQLLNTDYAKENQSLKKEVKELRSTNKSLSEENGRLKSTVEHLTNEIESLYVLTKDFLKARTNDLESFKELFGVFVGKVKEKAPRGLFVRQHERSEEKKNTFSLQDVLQRDRELREQRKAKRKKSHDLER
What is the function of this protein?
The interaction of the RSA site and the pre protein may not only serve a function in plasmid maintenance, but also contribute to the distribution of small antibiotic resistance plasmids among Gram-positive bacteria.
What are the official names of this protein?
Plasmid recombination enzyme.
What is the protein family that this protein belongs to?
Belongs to the plasmid mobilization pre family.
Protein: FKBP_KLULA
Sequence: MSETIEGNVQILRLSPGDSTNFPKPGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDAAIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNATLVFDVELLKIN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1, FKBP, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2028_ARCFU
Sequence: MLITITSMSAGRLGKIGLVAMIIVLTIITINTSAAPLEVSIEERVNSTINMTDAANGVGTFEYQTDVKGIINVTNNANEDIMDIWVAVDIGLNDGSCSAISTGVQILDSGDVPSKLTNEGGFDTSGADCIIHIPRLGPGESKYVAYDVTETPEIQNGAPFIVEEKYDPAKIPKGGDYTWTVYFNVSLNDTWWSSTGLGGKPSSVTLTVNKNLNTSYDTNWKTLEFADGSSNPKQIISGTLDNNKWLTTTFKVKGNYSTDEAFVSRLVGFGEAYFQFGPINGNISGTKIIDVFAIGNASIGVNKSGPDNSNQWTGNVTIKNTATGLTYIVKSVKVWATDRNYNEINGARYENTTVNVQIGRDESFTSKDLSFQYDKVPIIWGNVTFRLVEDANYGWGVGQDKITDGGNTYIIERIYVIGSYLVKVTKHVESAGNDIYNITLVVENLGGQESPYVYVYDLIPKNFSLTNGDNDWKDPQDRDGDWVNKSSMLAGGPETITNIQLSGYDTGYWWRIRPINASADGDGAYDDYTEIENNQTVVIFYQIQGSEDYKLLDAFIVGIDPILSMNEQTSPKITLVSGAKATSYESVMALATALVGLTAVVGYRRRS
What are the official names of this protein?
Uncharacterized protein AF_2028.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1393 and MJ1394.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SDHB_PEPAS
Sequence: MTDYSAFEVMGPIMVGPSSSHTAGACKIANVATSIVSNNYNQVEFQLHGSFAHTFKGHGTDRALVGGILGFEPDDDRIKTSFELAKQAGLNYIFTTTNLGDNYHPNSVKIVFSYPNGEEEYVIGSSIGGGAMKIVNINGIAIEFRGEYSTILLEYPEQRGVISYVSSLLTGSEYNIESLNTKKNKLTNIVTLTVEIDKPLTESLKSAILGVERFTTAKYVEV
What are the official names of this protein?
L-serine dehydratase, beta chain, SDH, L-serine deaminase, L-SD.
What is the protein family that this protein belongs to?
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Protein: AROE_PSEAE
Sequence: MDRYCVFGNPIGHSKSPLIHRLFAEQTGEALVYDAQLAPLDDFPGFARRFFEQGKGANVTVPFKEEAYRLVDELSERATRAGAVNTLIRLADGRLRGDNTDGAGLLRDLTANAGVELRGKRVLLLGAGGAVRGVLEPFLGECPAELLIANRTARKAVDLAERFADLGAVHGCGFAEVEGPFDLIVNGTSASLAGDVPPLAQSVIEPGRTVCYDMMYAKEPTAFNRWAAERGAARTLDGLGMLVEQAAEAFFLWRGVRPASAPVLETLRRQLATV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RRAAH_PSEPG
Sequence: MQHYVTPDLCDAYPDLVQVLEPMFSNFGGRDSFGGQIVTIKCFEDNSLVKEQVELDGKGKVLVVDGGGSLRRALLGDMLAEKAAKNGWEGLVIYGCVRDVDVLIQTDVGVQALASHPMKTDKRGIGDLNVVVAFAGVTFRPGEYVYADNNGVLVSPSPLEMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ACDE2_METTE
Sequence: MVDTTKNTKLFTSYGVKTSKAITTEVAAKLISKAKRPLFVVGTGVLDPELLDRAVKIAKAKNIPIAATGSSMPGFVDKDVNAKYINLHQLGFYLTDPDWPGLDGNGNYDTIILLGHKKYYINQVLSAVKNFSDVKSISIDRNYIQNATMSFGNLSKADHIAALDEVIDLL
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.  The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit epsilon 2, ACDS complex subunit epsilon 2, ACDS complex carbon monoxide dehydrogenase subunit epsilon 2, ACDS CODH subunit epsilon 2.
What is the protein family that this protein belongs to?
Belongs to the CdhB family.
Protein: SYV_LEIXX
Sequence: MPEKPALEGLEGKWGSRWQEDGTYLFDRAAAIAAGRDAVYSIDTPPPTASGSLHIGHVFSYTHTDVVARFQRMLGKRVFYPMGWDDNGLPTERRVQNYYGVRCDPTLPYEPGLTPPFEGGDNKSSKAADQKPISRRNFIELCERLTVEDEKQFEALWRSLGLSVDWSQTYRTIGEESLRTSQLAFLRNVKRGEAYQALAPTLWDITFRTAVAQAELEDRDQPSAYHRVAFHGEAGPVFIETTRPELLPACVALVAHPDDERYQPLLGTTVRTPVFGVEVPVVAHHLAQPDKGSGIAMICTFGDITDVTWWRELDLPNRAIIGFDGRIVSDAPEAIDTEAGREAYAQLAGKTVFSAKQTVVELLRASGDLVGEPKPIQHPVKFFEKGDKPLEIVSTRQWYVKNGARDEELRERLIELGRGIDWHPDFMRVRYENWVNGLTGDWLISRQRFFGVPIPVWYPLDAGGNPVFDAPILPLEESLPIDPSSAAAPGYTEQQRGQAGGFVGEHDVMDTWMTSSLTPQLAGGWHRDDELFAAVSPYDLRPQGQDIIRTWLFSTLLRSQLEDGVAPWTHAALSGFIVDPDRKKMSKSKGNVVTPADVLERHGSDAVRYWAASSRLGTDAAFDPQNPTQIKIGRRLAIKLLNAAKFILGFDAPASLDLAQVTVPLDRSMLQQLTDVITDATAALDAYDHARALETTETFFWTFCDDYLELVKERAYGEASTGQVSAVVALRMALSAFLRLFAPVLPFAAEEAWRWWNEGSVHLAAWPAAAETSVGGNDARAVLNVLGRALTGIRGAKTAAKASQRTPVDSAVIAGPAGDLAVIESAADDLRSVGRIVELRFTAGADLAVADIVLTQAPEEER
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOJAP_PSEAB
Sequence: MQTEQLVQVAIDALEDLKAQDIVTLDVRDKTSVTDYMVIACGSSSRQVKSLADNVLTKAKENGVKPLGSEGLESGEWALLDLGDVVVHVMLPATRQFYDLERLWQGAEQSRAQHQPEE
What is the function of this protein?
Functions as a ribosomal silencing factor.  Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8.  Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
What are the official names of this protein?
Ribosomal silencing factor RsfS.
What is the protein family that this protein belongs to?
Belongs to the Iojap/RsfS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_EXIS2
Sequence: MSVTLKVEEREVRPRSLRKQLRHEGKALGVVYGYKVESTPISFDEKELVKVIRDHGENVLVALQIGGKKVNTLINKLDMDIFTPTIKHVEFIAVKMDEETEVETDIVLVGEAAGAKLGGFLSQTLFKVTVAATPDKLPERIEVDVTELAIGDSITVADLPEEKDFRVVTEGDIQVAAVVESTLEAELEEIEEAEAEAQATDADTATDDSEQTSEEQAEENKEDKE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TRUB_BRADU
Sequence: MGGNSQPHQEPRRVNNDPRAKQQKGNQVRRDRRDVHGWVVLDKPIGMTSTQAVAVLKRLFNAKRAGHAGTLDPLASGGLPIALGEATKTVPFVMDGRKRYQFTVCWGEERDTDDIEGRVTATSELRPTREAILALLPRFTGVIEQIPPRYSAIKIQGERAYDLARDGEVVELAPRPVEIHRLTLVDQPDNDRAVFEAECGKGTYVRALARDMGRILGTYGHICALRRTLVGPFGENDMIPLDQLEALCDRAASGEGSLADALLPVETALDDIPALAVTRADAARLHRGQAVLLRGRDAPTCSGTVYVTVAGRLLALAEVGNGEIIPKRVFNLTGLTASPGRNERN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ILVD_BACC4
Sequence: MRSDMIKKGFDKAPHRSLLKATGLKDEDFDKPFIAICNSFIEIIPGHKHLNEFGKLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAALRINIPTVFVSGGPMAAGKTSKGEVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILAIDPRREELIKQAAEKLKILIERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLALAQEAGLDYDMNRIDAVSRRVPHLCKVSPASNWHMEDIDRAGGISAILKEMSRKEGVLHLDRITATGQTLRENIAEAEIKDKEVIHSLENPHSEEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPGMPEMLAPTSAIAGMGLGAEVALLTDGRFSGASRGISVGHISPEAAAGGMIALLEQGDIVCIDVEERLLEVRVSDEELEKRKKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLKIPNFD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MDH_RHOP5
Sequence: MARDKIALIGSGQIGGTLAHLVGLKELGDVVMFDIAEGIPQGKALDIAQSSPVDGFDAKFTGANSYEALDGASVCIVTAGVPRKPGMSRDDLLSINLKVMEQVGAGIKKYAPNAFVICITNPLDAMVWALQKACGLPHNKVVGMAGVLDSARFRYFLADEFNVSVEDVTAFVLGGHGDTMVPLVKYSTVAGIPLPDLVKMGWTSQARLDEIVDRTRNGGAEIVNLLKTGSAFYAPATSAIAMAESYLRDKKRVVPVAAYLNGEYGVKDMYVGVPVVIGAKGVERIVEIELAGKDREAFDKSVGAVQGLVEACKKIAPELLGA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: GCST_CHLL2
Sequence: MKKTALYSWHEQAGAKIIDFGGYLMPVQYSGIIAEHKAVREAAGLFDVSHMGNFYVRGVRAGEFLQYLTTNDLSKVSDGEAQYNLMLYTDGGVVDDLIIYRIDAETYFLIVNASNAQKDYAWIQKHIGAFEGVSLEDRTDELSLVALQGPMSGAILRKVFPDEDCNTLASFRFRKVYYNGTELLIARTGYTGEQGVEICLPNEAALELWSVLMKAGEEYGIQPIGLGARDTLRLEMGYSLYGHEIDSTVNPLEARLKWVVKMEKGPFIGKEACRQVELNPRYAVAGFSLDGRALPRQHFRLYNSDRQEIGTVCSGTLSPTLQEPIGTCSILREYSRPGTHVMVEIRGTMHQGVIRALPFVQR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: TKT2_VIBVU
Sequence: MDRKQLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHNAEAINAAIEAAKADPRPTLICTKTIIGFGSPNKSGSHDCHGAPLGAEEIAATRKELGWEHGPFEIPQEVYAEWSAKEAGAAKEAAWNEKFAAYEAAYPELAAEFKRRVNGELPAQWEEKANQIIADLQANPANIASRKASQNALEAFGKMLPEFMGGSADLAPSNLTMWSGSKSLEASDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQPRSAEQVADIAKGGYILKDSDGKPELILIATGSEVELAVKAAEQLTAEGKKVRVVSMPATDTFDKQDAAYREAVLPSDVTARIAIEAGIADFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFTVENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 2, TK 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: RL27_BIFLS
Sequence: MAHKKGASSSRNGRDSNPQYLGVKKFGGEAVVAGNIIVRQRGTNFHPGHNVGMGKDHTLFALTDGSVKFGVRRDRKVVDVIA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RRP36_TALMQ
Sequence: MAISDALNKRLRARRDEEEEEDDFEDELLSDEMEGSEEDGRSNSDEEQEDSNSDAAESEEDDDQDDEQDGDEDLSDAQSIQSANDREAIQSEFRQISFGALAKAQNSIGKKRKRGAEDKSDTRTDDKKPSSTLDDIRERLRKAREQKLGLTNNNNNNNNQNNNNGYHSKPKPPPRSSKHAPAVQSSKVAVSRKRTIIEPTTVKSRDPRFDPTVVKSSSSVRRNNSSAENAYSFLDEYRASEIKQLKEQLSKTKDATQKEELKRAITSATDRQRALDNRKREREVLQEHKKKEKQLIKEGKKSQPYFLKKSELKREVLKKKYESMGSKERAKALERRRKKVASKEKKDLPWARRGMEN
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RBM34_RAT
Sequence: MALRGEGRKRKKGQERRQSSEDDVGNAATDYLVGQVADSLRGGARPPGGGTGRLAALFSTPETLAPPVFVPVPQETSKKRKPDDEEETVAHIKKPALQEPARKVKVKKLSDADKRLANRESALANADLEEIRQDQGQGRRRSQSRGKVTDGEALDVALSLNEDGRQRTKVPLNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLSKKLAAIKRKFHPDQKSINAYVVFKEERAAAKALQRNGAQIAEGFRIRVDLASETASRDKRSVFVGNLPYRVDESALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVNKEKLKQQNSNPSVKKDGSKSKQRLNFTSKEGKSHSKNAFIGEKAVLMKKKKGQKKKGQTKKPRKQK
What are the official names of this protein?
RNA-binding protein 34, RNA-binding motif protein 34.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y1595_MYCMM
Sequence: MSITKNAPREGAEEVAATALGVAAARAAETRRQRPLIVDPFAQLFVDAAGQDLWSMVASGAAHDELASADPALAAVMQTSLGHIASRTKFFDEFVLAAADAGIRQVVSLGAGLDTRAWRLSWPDAVTVYELEQPNVLEFKLATLRDNGATPAANYVDVPVDLHRCWPRSLCLAGFDPAAPTAWLVEGLLPFLSVAAQDLLFGDVHKLSVPGSWLAAEALSSEFLKPTTVARQRARIRRMRVTAATLAGLSNVTELWDLAEGRSDVADWLRGRGWHASVLTAERLLARYHRSAPVELGDATPPSLYVTARLSAESSLDA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_1595.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: APT_CORDI
Sequence: MTVPLYADAREAIACKTRFVPDFPVPGVIFEDLTPVLADAAAFSLIVDELAKNAMRLGADFIGGLDARGFLLGSAVAYKAGTGILAIRKKGKLPPPVHSEEYSLEYGTAALELPAEGLELEDKKVVLVDDVLATGGTLDAARKLIEACGATVSGYAVVLEVDGLGGRERLNDAPLVVINESATA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.