PharMolix/UniProtQA huggingface dataset:
Protein: EFP_ACHLI
Sequence: MVSTSDFKTGLTIEVDGQIYVILDFLHSKTARSGALINTRLRNLRTKNIQEITFKSGDKVERAIIDRIKMQYLYASGDTHVFMNMETYEQIEVDKSQIEYELNFLYESLEVEINFYGTEIIGVNLPEKLVLEVKETVPGVKGDTKTNAMKDAYLASGYLVKVPMFIETGEKIIVNTTEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_CUPTR
Sequence: MEFSTKALDWSKAGQNGFLATKTDCLVVGLFEGQNLGGVAKALDVATKGLVGRLVKQGDFEGKRGTHLMLHEVAGVGAARVLLVGLGKEADFTDKAFADAVRTAVRALSSTRATSALWCLAQQAPQQRDVSWAVITTITLVREAGYRLLERHPGLKRANAQNAASGKPNGNDKSSLRKVVIAVDSGDARAATQAAVRGTAIANGMELTRDLGNLPSNICTPTYLANTARSIAKRHKLKAEILGRKQIEALNMGAFLAVTKGSAEPPQFIVLRYDGGGARQAPVVLVGKGITFDTGGISLKPGEGMDEMKYDMCGAASVLGTIQAVAEMGLKLNVVAVVPTCENMPSGVATKPGDVVTSMSGQTIEILNTDAEGRLILCDALTYVERFKPAAVIDVATLTGACIIALGHVNSGLYARSDALADALLQAGRRAMDTAWRMPLDDEYQDQLKSNFADMGNIGGRPAGSVTAACFLARFTEKYDWAHLDIAGTAWKSGAAKGATGRPVPLLTQFLMDRAA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICR5_ARATH
Sequence: MQTPKSRPGSLELPQKKSPLPAPKVVRRLKPSGAESDPKTKTISKTQIPKVVADRRSARIPLNEIQKKRTGRIPELESTISQLQEELKKAKEELNRSEALKREAQEEAEDAKHQLMDINASEDSRIEELRKLSQERDKTWQSELEAMQRQHGMDSTALSSAINEVQKLKSKLFESESELEQSKYEVRSLEKLVRQLEEERVNSRDSSSSMEVEELKEAMNLSRQEITQLKSAVEAAETRYQEEYIQSTLQIRSAYEQTEAVKSRYSQREAELTEELNRTKDEIEGLRKELMEKVKEDESTGDLKKLESDLMEVRGSLMDKEMELQILRSAMEKKVETANTEAMEAELKRVKIQCEQWRKAAETAASILNNDEERTDSIETSKMLKKFGVLLKKNHK
What is the function of this protein?
ROP effector binding specifically activated ROPs and linking them to the microtubule cytoskeleton.  Involved in ROP-regulated polar growth.  Involved in local disassembly of cortical microtubules when associated with ARAC10 and KIN13A and conversely mediates also the elimination of ARAC10 from the plasma membrane by the cortical microtubules.  Accumulates at the plus end of shrinking microtubules.  Targets KIN13A to microtubules.
What are the official names of this protein?
Interactor of constitutive active ROPs 5, Protein MICROTUBULE DEPLETION DOMAIN 1, ROP-interactive partner 3.
What is the protein family that this protein belongs to?
Belongs to the ICR family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton. Note=In xylem cells, preferentially colocalizes with cortical microtubules located beneath the secondary wall pits (PubMed:20619818). May be associated to the plasma membrane through the interaction with ARAC10 (PubMed:22984069).
Protein: RIB3_YEAST
Sequence: MFTPIDQAIEHFKQNKFVIVMDDAGRENEGDLICAAENVSTEQMAFLVRHSSGYVCAPMTNAIADKLDLPLLRTGMKFESNDDDRHGTAYTITVDVAQGTTTGISAHDRSMTCRALADSSSTPKSFLKPGHICPLRAADGGVLQRRGHTEAGVDLCKLSGLSPVAVIGELVNDDEQGTMMRLNDCQAFGKKHGIPLISIEELAQYLKK
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (Probable).  Has also an unrelated function in expression of mitochondrial respiration (PubMed:12595523).
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: RMD_ANETH
Sequence: MRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMISLDIMDSQRVKKVISDIKPDYIFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVLDAVRDSNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAYWLLSQYGKTGDVYNVCSGIGTRIQDVLDLLLAMANVKIDTELNPLQLRPSEVPTLIGSNKRLKDSTGWKPRIPLEKSLFEILQSYRQA
What is the function of this protein?
Reductase that catalyzes the conversion of GDP-6-deoxy-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose (GDP-D-rhamnose).
What are the official names of this protein?
GDP-6-deoxy-D-mannose reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-6-deoxy-D-mannose reductase subfamily.
Protein: OMCBH_CHLTH
Sequence: MNKLIRRAVTIFAVTSVASLFASGVLETSMAESLSTNVISLADTKAKDNTSHKSKKARKNHSKETPVDRKEVAPVHESKATGPKQDSCFGRMYTVKVNDDRNVEITQAVPEYATVGSPYPIEITATGKRDCVDVIITQQLPCEAEFVRSDPATTPTADGKLVWKIDRLGQGEKSKITVWVKPLKEGCCFTAATVCACPEIRSVTKCGQPAICVKQEGPENACLRCPVVYKINIVNQGTATARNVVVENPVPDGYAHSSGQRVLTFTLGDMQPGEHRTITVEFCPLKRGRATNIATVSYCGGHKNTASVTTVINEPCVQVSIAGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVLEAAGAQISCNKVVWTVKELNPGESLQYKVLVRAQTPGQFTNNVVVKSCSDCGTCTSCAEATTYWKGVAATHMCVVDTCDPVCVGENTVYRICVTNRGSAEDTNVSLMLKFSKELQPVSFSGPTKGTITGNTVVFDSLPRLGSKETVEFSVTLKAVSAGDARGEAILSSDTLTVPVSDTENTHIY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.  It is present but the disulfide bonds are reduced in reticulate bodies (RBs) (By similarity).
What are the official names of this protein?
Large cysteine-rich periplasmic protein OmcB, serovars D/H/G/K, Large-CRP, 60 kDa CRP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: DCD_LEGPH
Sequence: MSIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNINSAIVDPKAFDENSFVDVQSDVCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFLEANEVCAVSYRDRNGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: NADK_CHLPB
Sequence: MKFGIVVNINRKDALELASELVIWLKNRSLDYLFDSLSAKALNVNESSPIEAMNTHCDVFISLGGDGTLLFTSHYSVTKPVIGINVGHLGFLTEFSKEEMYGAIEKVLNGSYTIYERTQLEAHIDVEHEKKRFTALNDVVIEKGTYSRIPTFNIKLDDEQLSAYRADGIIIATSTGSTAYSLSAGGPVIFPKSNVFVITPICPHMLTVRPIVISDDKHIEVFVDAPDGEFPLNCDGHQRKLLLPGEVISVKKSEEMINLVANENRNYCEILRSKLLWGREHKPGL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_TRIL1
Sequence: MKLIVAGGGTGGHLFPGIAVAEEFLSRDPANQVLFVGSERGIEARAIPRLGYQLELISAAGIRGKGSLAKLKGAAMMIYGYAQSRKILHRFQPDLVLGVGGYASLPMVMAARGMEIPRYIHEQNALPGMSNKVLSRVANKVFISLEESAKFFPKDCTLLTGNPLRKQILEMLTQTETENPPSIPPLLKGGSEPCEQRGFNLFIFGGSQGAHALNVALPQAVAQLSPKQQRLIKIIHQTGEADLQQVQAAYQANGLEADVRPFIDDMATAYRQADLIICRAGATTIAEVTALGKACLFVPFPHATDDHQRKNAEALLKKGACEMLVEQEIGGKGLSEAIARLMENRDALKLIGENAAALARLDAARVIVDQMLEGVQPCTET
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARLY_SACS2
Sequence: MLYRKWGSEKDEVVNYTSSVDSDREIIEEVKLTMKAHVISLYLTGYLGKETARKILVALNEFKEIGQGYEDIHEALEDFLIKKVGEDAGWIGLGRSRNDHVATALRLRLRNKLIELLTDINSLRKILLDKAKEHITTIFPSYTHLQLAQPTTFAHYLTYIEEELASRWEIIFSTLKQVNKSPLGSGAIVGTNVKIDREKEAELLGFDSIIYNTLSATSSRADILSTISELTVLMVVLSRIAEDLIFFSSNKLIKLPDSHVSTSSLMPQKRNPVTMEILRAKAAESIGMLTSLLSIYKGLPTGYNLDLQEMNKYYWLVINYTKSSIGVLSSLFSQIQVNKINIDESSLATDDAELLSISKKVPYRSTYFEIAKKVREGSYKSTLKIEDSINMKAVIGSPNFDLMANLIKIRETKLKEDEKEIEEYKLKIISKLGELQVIENEIGE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_PASMU
Sequence: MKDYSHLHIGVLALQGAVSEHLRQIEQLGANASAIKTVSELTALDGLVLPGGESTTIGRLMRQYGFIEAIQDVAKQGKGIFGTCAGMILLAKQLENDPTVHLGLMDICVQRNAFGRQVDSFQTALEIEGFATTFPAVFIRAPHIAQVNHEKVQCLATFQGHVVLAKQQNLLACAFHPELTTDLRVMQHFLEMC
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: GCSPA_DESVH
Sequence: MPFVPHSPEDVSVMLDAIGVNTIEDLFADIPAEMRPKSFALPKGLSEMDVCSRLEALSARNRTDVVSFLGAGFYDHHIPKAVDALSSRGEFYTAYTPYQPEAAQGTLQAIFEFQTAVCRLLDMDCANASVYDGGSALFEAMMMAVRATRRRKLVIDEALSPIYRTMLASYTSNLQLELVTVPHRDGLSDMDALKASVDDTCAAVVVQNPNFFGAITDFTDLFTHARAHKALGVISVYPVMQSVLKTPGEMGADIAVADGQSIGQPLSFGGPYLGIMTCTKPLVRQIPGRIVGRTQDVDGRTGYVLTLQAREQHIRRAKATSNICSNQALCALRSLIHLTLLGPEGLVRTAELSMERARYAAERLTALPGVELLHDAPFGNEFAVRLPVSAFEVVDRLTARGYVPGFPVGRYYPGMDNVLLVACTEKHSFEQVGILAEMLGGIL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: PSBC_ATRBE
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLGALAVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TTC17_DANRE
Sequence: MTRSFRVEWTDGRKMADDKSNSIGDNSTNKRLWSSSIRGSALIFICALLAEPARATTHWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDADCVTAKVPLGDLDLYDGTFISLESKDINPEQFLDLMSALPPDLEKPDCAKLLDLPYSIHAFQHLRGVQEKVNLTSPLLSKDDPIFTSLCLKLGQSVDEVGHRIHQALLKNSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHFSADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPGFEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHYLRQQEMLDKHKLIQEEQILRNIIHETQMAKEAQLGNHQMCHMGQQKFTLHCPFDLPVRYHRGELFENVHYIQFGEEVSVASSVALVSELSVNESHSPQQSYTVSLGREPAAHWDKETTTTDESRTVLWPRRSDCAQRFPTIPPAYLLPTYYLPPESRNLKALNILLESISPPPSAKMPDCSLKNVVGNRDPLESMSWALEKELRDPQAAEVLLKRSGGRSLEQTGALIAQALEKMSGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLLLHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGALAVFRQALSLSVHCGQCRASLPLMRCLQFYPFLYNLQHQACSSGGACEVEEDSELEDWDTGSSSSGRQEVWDSDAMPVSALEDSLLFEKVVVDSNGSGEASGQDRTREPKAEGGEEEEQDWRLREELIGAFEGALDMNGKTGDLRGIRVLKNDRVMGARGGGPCFGNCEDDEGAEWITFQVKRVKKPKSDASEGWVGEGDVRQTEPTASNSILEISGPTIPSPGPSERWKDYSSLGWPGPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATPLQEPAVEPVCNANLPASMHTLDHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQCYLLSKRDRRAP
What is the function of this protein?
Plays a role in primary ciliogenesis by modulating actin polymerization.
What are the official names of this protein?
Tetratricopeptide repeat protein 17, TPR repeat protein 17.
What is the protein family that this protein belongs to?
Belongs to the TTC17 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton.
Protein: RK14_WELMI
Sequence: MIQSQTYLNIVDNSGARKIMCIRVVGASYQRYAHIGNVIIAVIKEAVPNTKMEESEIVRAVIIRTSKEFQRDDGMRIRSDDNAAIIIDQKGNPKGTRVFGPVLQELRQYNFTKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NS1_I24A0
Sequence: NTVSSFQVDCFLWHVRKRFADLELGDAPFLDRLCRDQKSLRGRSSTLGLDIETATRAGKQIVERILEEESDETLKMTIASAPAFRYPTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGDLIGGLEWNDNTVRVSETLQRFAWRSSNEGGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RTNLD_ARATH
Sequence: MVEDHKHEESILEKIVEKIHGHGDSSSLSDSDDDKKSTSSSSSSFKSKIYRLFGREKPVHKVLGGGKPADIFLWRNKKVSGGVLGAVTASWVLFELFEYHLLAFLCHFAIFALAALFLWSNACTFIHKSTPHIPEVHIPEDPILQLVSGLRIEINRGLTLLRNIASGKDVKKFILVIAGLWVLSIIGSCYNFLTLFYTATVLLFTIPVLYEKYEDKVDAYGEKAMREIKKQYAVLDEKVLRKVISKIPRGALNKKKD
What is the function of this protein?
Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.
What are the official names of this protein?
Reticulon-like protein B4, AtRTNLB4, VirB2-interacting protein 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y0809_DICDI
Sequence: MISNKRKEIDTINEHHEKNNDDSDGIDNGLLTYKKFKKDFESGSTNYRELQIIAKSLGLASNGKKQLVYNRIEGYFLSKKVKNNLTNNETNRQVEKKKEQQQPQPQEKQYILTFKDVEPVEIYFWKIFRNIVIFKHIFSNFKSKQYSYYDLIGCDEILLNGKSNSMEIIIDNIKSYNHQIIRNESNIIDIINKFKKNDEKTRSFYNLLFSRYSSTSTSPSTQLPSTIQFDGNIDIWIQRMIENVNYTALDQFIKFFKIDSEVIKKAIKIHIDPSFFGNTTYDKLKIYNYLKSINSIPTSHTLLSTISINFSTLLSFDNKFKKLIKSYKRLIESTNLQEQQEQLEKQGIIKIHPNKKYYEKLNQKILELNEIQTSQFTNYQLNSTIKKLLNHTTPTSTSTSTSTSTSTYTSTSTSTSTSLKTTNLTIISTESNYSSTNNNNNNINLKEIIKKYYKSIYLFIYFTINSANKTIFRKPLLYYLYFKKERVDKMYEHVIKKWNGSNFDHKLFFQRIFKDIKIEKNEKFELISNVLNNKYVKTFKLKDLHIFFEAVFSSNDIELIDYFLKILKQQQLNQTPETTTFPVIGSLISDYCHFIDKKEILDFYFQNYRDECLLFNDQNQTWKRIQLGLIEHYEYLTGSIGNRCNFDIFRWFDSSKFLDRLNRTIAKPLLYYFDFRGTINFNFNFIFKGLIDSNTEDSKENSIIHFLSNAQLKHPLYVSPILESSFNRYKSKMLTFIKFLFNNISKESIETKLKVINLKTDNKNFEEINSEIVLTTTLTTTTTTTTTTTTGTTATATNLLSAKKGEDVGFFIIGQTESFNFTVSIRILLVCLYRLDRVDDIIYLFDKLPEVLFNPDYFSIFTKEHCLYGISSSYYLELFINYFIENLNNNTINYLYNCLCIASKKGYTQIFKNIISSDHNSKYLLKIRTKSNQSSLFSSKLLNDIVVKSINSLNFELSNLLIDFIDFSEKDKNTLKMKIIKSK
What are the official names of this protein?
UPF0746 protein DDB_G0280809.
What is the protein family that this protein belongs to?
Belongs to the UPF0746 family.
Protein: MNME_PARUW
Sequence: MEFIHQPYYPGETIAAIATPPGEGGVAIIRISGDQSLEVAAKIFSGPIFSYRSHTAHYGQIYNSSGEHVDDVLVLIMLGKRSYTGENTVEIHCHGGSLITRKVLEVVLAAGARAALPGEFTFKAYMNGKIDLAQAEAVQELICAKNEKALGAAESQLKGSLSNRVLAFQSTLTQIAAILEAWVDFPEEGLEFATMDELDQDLERTAKDMEKLVNSFHNGKILHDGLSICLIGCPNVGKSSLMNALLDKDRAIVSPIPGTTRDVLEDHLRLNGLHIKLSDTAGIREANESVEQEGIRRSKKAMQEADLILLVLDAHKGLEKEDQELLKQVPFHKTIVIWNKIDLNPRNLPCLEVPFLVHLSAKEKIGLEELHQTIDTIIWQDGPPSKEEILITNVRHKEALIESIESLRRVKIGLRHQVSPEFLTLDMRQSLLELGKIIGTNISEDILSAIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_FRAAA
Sequence: MSLLVVGLNHRTAPTSLLEQASVSGDDTPKVLHDLAAAAHVNEAVVLSTCNRTEIYADVETFHGGVADISDQLSRISGIDLGDLAGHLYVHHDARAVGHLFSVVCGLDSMLVGESQILGQVRGAFRTGQSAGVAGSALSGLFQAALRVGKRAHSETSIDAAGASIVAVGIRLAASSLGILSEVPAVPVAPPGGVAGELGGAAVLAAPVAEPPPLAGARVLLIGAGAVGSLAAQTARRAGATEIVIANRTPARAARVAEMHDGRAVGLTDLPHEILMADLVISSTGATGLVVDHDLVAAALPGRGGRPLVFLDLALPHDIDPGVRALPGVSLIDLEALRVALDGAQVAHDVEAVRALVSTEVAGFLDRRRAGRVAPTVVALRAHADSVVHGELARLHSRLPDLDDREWELVEGAVRRVVDKLLHAPTVRVQQLAGAPGGDSYAEALRELFDLPREVPAVVSAPDLDLVERS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HIF1A_MOUSE
Sequence: MEGAGGENEKKKMSSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGGLDSEDEMKAQMDCFYLKALDGFVMVLTDDGDMVYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVRKGKELNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTESVLKPVESSDMKMTQLFTKVESEDTSCLFDKLKKEPDALTLLAPAAGDTIISLDFGSDDTETEDQQLEDVPLYNDVMFPSSNEKLNINLAMSPLPSSETPKPLRSSADPALNQEVALKLESSPESLGLSFTMPQIQDQPASPSDGSTRQSSPERLLQENVNTPNFSQPNSPSEYCFDVDSDMVNVFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESNSPSPPSMSTVTGFQQTQLQKPTITATATTTATTDESKTETKDNKEDIKILIASPSSTQVPQETTTAKASAYSGTHSRTASPDRAGKRVIEQTDKAHPRSLNLSATLNQRNTVPEEELNPKTIASQNAQRKRKMEHDGSLFQAAGIGTLLQQPGDCAPTMSLSWKRVKGFISSEQNGTEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
What is the function of this protein?
Functions as a master transcriptional regulator of the adaptive response to hypoxia (PubMed:15225651, PubMed:17981124, PubMed:22009797).  Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia (PubMed:15225651, PubMed:17981124, PubMed:22009797).  Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease (PubMed:22009797).  Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (PubMed:26245371).  Activation requires recruitment of transcriptional coactivators such as CREBBP and EP300.  Activity is enhanced by interaction with NCOA1 and/or NCOA2.  Interaction with redox regulatory protein APEX1 seems to activate CTAD and potentiates activation by NCOA1 and CREBBP.  Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia (By similarity).
What are the official names of this protein?
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with HIF3A isoform 2 in the nucleus and speckles (PubMed:21546903). Cytoplasmic in normoxia, nuclear translocation in response to hypoxia (By similarity).
Protein: ZN474_HUMAN
Sequence: MERGKKKRISNKLQQTFHHSKEPTFLINQAGLLSSDSYSSLSPETESVNPGENIKTDTQKKRPGTVILSKLSSRRIISESQLSPPVIPARRPGFRVCYICGREFGSQSIAIHEPQCLQKWHIENSKLPKHLRRPEPSKPQSLSSSGSYSLQATNEAAFQSAQAQLLPCESCGRTFLPDHLLVHHRSCKPKGEGPRAPHSNSSDHLTGLKKACSGTPARPRTVICYICGKEFGTLSLPIHEPKCLEKWKMENDRLPVELHQPLPQKPQPLPNAQSSQAGPNQAQLVFCPHCSRIFTSDRLLVHQRSCKTHPYGPKYQNLNLGSKGGLKEYTNSKQQRNRAAPSVTDKVIHATQDALGEPGGALCL
What are the official names of this protein?
Zinc finger protein 474, Testis-specific zinc finger protein, TSZFP.
Protein: RF1_UREPA
Sequence: MEYNKKLYEAIERVAIKNDALKKELETVVTDFKKIKEINIQLKKTTKIAEAFAKYKQKLDTGIAAEKILNTEKDLELIELAQMDLDEAKINIPIIENDLKIMLLPTDPNDDKNVIVEMRPAAGGDESSIFVGNLFDTYRAYAENNNWKMKIIEMTPNAVGFSFISFMISGEEVYSRMKFESGVHRVQRVPATESKGRVHTSTITVAVLPEQDEVDVVINPTELRIDTYRASGAGGQHVNRTESAVRITHIPTGVVAACQEGKSQIENRETAMKMLRAKLWEAAQEQQNAEFANLRKNQVGTGDRSEKIRTYNYPQNRVTDHRINLTLNKLDQIMMGELDEIIDALIADEQTGLMANLDI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK11_NEOYE
Sequence: MAKKVTGIVKLALNAGKATPAPPVGPALGQHGVNIVMFCKEYNARTADKSGLVIPVEISIYEDRSFTFILKTPPASVLIAKAAGLNKGSGEPNTKKVGSITNKQLESIAETKLPDLNTNNIPQAMKIVGGTAKNMGILIKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.