PharMolix/UniProtQA huggingface dataset:
Protein: CZCD_BACVZ
Sequence: MGHNHNHAGGSNKKVLLISFIMITGYMIIEAIGGFLTNSLALLSDAGHMLSDSISLMVALIAFKLAEKKASHHKTFGYKRFEILAAVINGVALILISLYIIYEAIKRFSHPPEVATTGMLTISIIGLAVNILVAWIMLNGGDTKNNLNIRGAYLHVISDMLGSIGAILAAILIIFFGWSWADPAASVIVAILVLRSGYHVTKDSIHVLMEGTPGNIDVTDIIHTIEETEGIQSIHDLHIWSITSGLNALSCHAVVNDQLTISESESILRKIEHELGDKGITHVTIQMETAAHNHDNTILCQSQTENPRDHHHH
What is the function of this protein?
Involved in divalent cation and potassium homeostasis in the cell.  Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions (By similarity).
What are the official names of this protein?
Cadmium, cobalt and zinc/H(+)-K(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRIO_HUMAN
Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, ASCR, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: FLA1_BARBA
Sequence: MGSSILTNRSAMTALQTLRNIDNNLDKSKDRISTGLRIGSASDNTAYWSISSMMKHDSNTMSAVVDAINLGREQVNVAATAVNLTKESLDDIQKSMVSAREKSDDDIMKIQDSIKGNMQNISNAIQSAAFGGKNILSNGGEKVGIAAGYRREGSAVYVDMIEVGGAELNFGVMGPDGTIDMTQGILKGVFGKSDKDIDAGIKTFTEAADKQKGLEDALAKAEAAVAANPNDEAAKTALEEAKKAVEDNKEDWTKAQSDFKVVADSMTLNDFVQMQGVGGLPSVAQSIILNSVQKTVRHAVDVTLTAGSKIGSAVNQVDSQLNFVKRLLDNIEAGIGALVDADMNAESAKLSALQVQQQLGIPRLFLLQIRAARIF
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Flagella are an important component in the invasiveness of B. bacilliformis.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: IF6_ASPOR
Sequence: MAVRAQFENSNEVGVFARLTNSYAVVAIGASENFYSVFEAELQDVIPICHATIAGTRIVGRLTAGNRKGLLVPTTTTDQELQHLRNTLPDSVKIQRIEERLSALGNVICCNDHVALIHPDLERETEEIIADVLGVEVFRQTIADNVLTGSYMALSNQGGIVHPKTSIRDQDELSSLLQVPLVAGSVNRGSAVVGAGMVVNDWLAVTGLDTTATELSVIESVFRLGEMGPRGVGMGSTNKESIVESFY
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  Is also involved in ribosome biogenesis.  Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: MSCL_PELPB
Sequence: MLKEFKEFAMKGNVVDMAVGIIVGGAFGTIVNTLVSQVLMPPLGLLIGGVDFTNLYLILKEGSKAAAPYAALADATAAGAVTVNYGLFLNSVISFLIMAFAVFLLVKAINMLRREEKAPPLAPTTKECPYCLSIVPLKATRCSSCTSELGK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARL11_BOVIN
Sequence: MGSVSSRGHRAEAQVVMMGLDSAGKTTLLYRLKGYQLVETLPTVGFNVEPLEEPGHVSLTLWDVGGQSQLRASWKDHLEGTDILVYVLDSTDEARLPEAVAELREVLDDPSVASVPLLVLANKQEVPQALSLPEIRDRLGLQGFLGRSWDLRACSALTGAGLPEALESLRSLLKSCSLCMAR
What is the function of this protein?
May play a role in apoptosis.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: RS12_BACAN
Sequence: MPTINQLVRNGRTDKVWKSKSPALNKGFNSLKKKSTDISAPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDKRMQGRSKYGTKKPKAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MURC_STRGC
Sequence: MTKIYHFIGIKGSGMSALALMLHQMGHKVQGSDVDKYYFTQRGLEQAGIKILPFDAKNIQADYEIIAGNAFRPDNNVEIAYANEHGISYKRYHEFLGSFMRDFVSFGVAGAHGKTSTTGILSHVLSNITDTSYLIGDGTGRGSAGAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFIYGEDEQLRRITSEAPIYYYGFEKGNDFVAHDLLRSTTGSTFKVSYRGQELGEFHIPTFGRHNIMNATAVIGLLYVSGFDLNLVREHLKTFAGVKRRFTEKVVNGTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAIFQPHTFTRTIALLDEFADALNQADAVYLAQIYGSAREVDHGDVKVEDLAEKIVKRVQVVSVDNVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANKMT_MOUSE
Sequence: MDQDDPAEALTELREKRLGLLEIVQAAAGSGLAVYTIWALLLQPGFRRVPLRLQVPYVGASARQVENVLSLLRGRPGKMVDLGSGDGRIVLAAHQCGLRPAMGYELNPWLVGLARLHAWRAGCSASVCYHRKDLWKVSLRDCHNVSVFLAPSVLQLLEDKLQAELPVGARVVSGRFPLPTWQPVAVVGEGTDRVWAYDVHGSGPTVSSCGVPIKAIPESSSTLVPRAPV
What is the function of this protein?
Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration.  Probably also trimethylates ANT1/SLC25A4.
What are the official names of this protein?
Adenine nucleotide translocase lysine N-methyltransferase, ANT-KMT.
What is the protein family that this protein belongs to?
Belongs to the ANT/ATPSC lysine N-methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: GGH_BOVIN
Sequence: MARLGRLLSVLGLVLCGATGLGLSAPPAPTPKKPIIGILMQKCHNKNMRALGKYYIAASYVKFLESAGARVVPVRLDLKNEEYEKLFKSINGVLFPGGSVNLMRSGYARVAKMFYNLSIKSFGEGDYFPVWGTCLGFEELIYLVSGESLLTLTDTVGIKLPLNFSRGTLQSRMFQNFPADLLLSLAVEPLTAHFHKWSLSVMNFTKNEKLKAFFSILTTNTDGNIDFISTMEGYRYPIYGVQWHPEKAPYEWGQLRGISHAPNAVKAAFYLAEFFVAEARKSNHHFESDVEETKALIYQYRPTYTGNVSSFQQSYIFD
What is the function of this protein?
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates.  Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate.  May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.  Exhibits either endo- or exopeptidase activity depending upon the tissue of origin.  When secreted, it acts primarily as an endopeptidase (By similarity).
What are the official names of this protein?
Gamma-glutamyl hydrolase, Conjugase, GH, Gamma-Glu-X carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Lysosome. Melanosome. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted.
Protein: SLYA_YERPY
Sequence: MESTLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISSDEIAVLSGLIDKLEKNIIQLQTK
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: RK20_STAPU
Sequence: MTRVKRGYVAVRRRNRVLERAAGFRGAHSRLFRPAKQQVMKALVASKRDRDKRKRDFRKLWITRINAAVRKQGMSYSRFIHQLYQSKILINRKMIAQIAVLDENGFTSIVNNI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNJC5_TETCF
Sequence: MGDQRQRSLSTSGDSLYIVLGLDKNASPEDIKKSYRKLALKYHPDKNPDNPEASEKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGVITGCYFCCCLCCCCNCCCGKCKPKPPEGEEQEYYVSPEDLEAQLQSDMEKEGDGAIVVQPTSATETTQLTSDSHPSYHTE
What is the function of this protein?
May have an important role in presynaptic function.  May be involved in calcium-dependent neurotransmitter release at nerve endings.
What are the official names of this protein?
DnaJ homolog subfamily C member 5, CCCS1, Cysteine string protein, CSP.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Melanosome. Cell membrane. Note=The association with membranes is regulated by palmitoylation.
Protein: RL32_SYNE7
Sequence: MAVPKKKTSKSKRDKRKATWKRKAALQAQRALSLGKSVLTGRAKGFVYPAQDEEETEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RL4_ORITI
Sequence: MKVKVYNLLQEIEKEVELNPSVFCLKYRPDIIKLVIDWQLAKRMSGTHCTKTISGVSGTTKKPFKQKGTGNARQGSLRSVQMRGGGISHGPVVRSHEFDVPKKIRKQALKYALSYKLSVNKLIVVDDFNIGSNKTAVLKNLLKKYNYSNYSGFFCIDDQNVDRNFFLASRNLFNLNVVAQIGANPYDIMKHDCVMVTLSAAKSLEMRLAE
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GATA_RUEST
Sequence: MSDLNKLGLAEARDLLRKGDTTSVELTEACLKAIDGADALNAFVHKTPDVALDRAKAADARIAEGDAPAMCGLPIGMKDLFCTKGVDSQAASNILKGFKPEYESTVSQKLQDAGAVMLGKLNMDEFAMGSSNETSAYGNAISPWRREGDETPLTPGGSSGGSAAAVAADLCLAATGTDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAFASSLDQAGPMTKNVRDAAIMLEAMCGHDAKDSTSVDLAVPNFEAMLTGDIKGKKIGIPREYRMDGMPAEIAKLWDEGAAMLKAAGAEIVDISLPHTKYALPAYYVIAPAEASSNLARYDGVRYGHRATLAQGDGITEMYEKTRAEGFGHEVQRRVMVGTYVLSAGFYDAYYNRARKVRTLIKKDFEDVFAAGVDAILTPATPSAAFGLGEMNDEDPVKMYLNDVFTVTVNLAGLPGISVPTGVDTQGLPLGLQLIGRPWDEGDLLNTAYALEQAAGFVAKPAQWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL36_PSEMY
Sequence: MKVRASVKKLCRNCKIIRREGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL33_ACIAD
Sequence: MRDKIRLVSSAGTGYFYTTTKNKRTMPEKMEIKKFDPKIRQHVIFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ACCD_HAEIG
Sequence: MSWINRIFSKSPSSSTRKANVPEGVWTKCTACEQVLYSEELKRNLYVCPKCGHHMRIDARERLLNLLDEDSSQEIAADLEPKDILKFKDLKKYKDRINAAQKETGEKDALITMTGTLYNMPIVVAASNFAFMGGSMGSVVGAKFVKAAEKAMEMNCPFVCFSASGGARMQEALFSLMQMAKTSAVLAQMREKGVPFISVLTDPTLGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDMIVKRSEMRQTLASVLSKLTNQPSPFVEPELISEDE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABA_STAES
Sequence: MNRNELFERLMKLEHHVEQLTTDMSELKDLTVELVEENVALQVENENLKRLMNKTEESVETHLDKDNYKHVKTPSPSKDNLAMLYREGFHICKGELFGKHRHGEDCLLCLNVLSD
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: DXR_PROMA
Sequence: MLGSTGSIGTQTLEIAKECPEQFKVVALTAGRNLDLLIKQIQEHQPEVVALARKDILPELQERLNSLTGKERPNALPHLVAGNDGLNIAASWHSADLVVTGIVGCAGLLPTLAAIKAGKDIALANKETLIAAGPVVIPELKRSGSRLLPADSEHSAIFQCLQGTPWPENARLSTGIPTPGLRNIQLTASGGAFRDWATEDLKHASIKDATSHPNWSMGKKITVDSATLMNKGLEVIEAHYLFGLDYDHIEIVIHPQSIIHSMIELNDSSVLAQMGWPDMKLPILYAMSWPNRINTSWRRLNLSEIGKLTFHEPDTSKYPCMELAYAAGKAAGTMPAVLNAANEEAVALFLEEKIHFLNIPKVIEAACENHKKDLKFDPQLQDVIEVDYWARREVRSQVQKDSNQITMATYKK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RDGC_PSYIN
Sequence: MFFKNLQVYRFTRPLEQDIDTLERNLEEFKFKPCGSQDISKLGWVFPMGKSGSMYTHIAGKQILICLKKEEKMLPAGVIKDQLNERVEAIELEQGRALKKKEKDSLKEEIVMQLLPRAFSRTSQTFAWIDSESDMLYVDASSTRKAEELISLLRKTLGSLPIVPIQLKNQADVIMTDWLTEGNIPANFALEDEAELCSALEGGGIIRCKQQDLLSDEIKNHLSADKFVTKLALCWADSISFIIGEEFALKRIKFADVLQEQNEDIDKDDFAARFDADFALMTGEIKQLIPAVLAAFGGEQSL
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL9_VARPS
Sequence: MQIILLDKVLNVGGLGDIVKVKDGYARNFLIPTGRARRATAANKAEFEAKRVELEKAAAAKLAESQAQGEKLGGTTVKLTQKAGVDGRLFGSVTNGDIAEELGKQGYKVAKSQVRLPNGPIKVVGDSTVSVALHTDVVVDITVTVYGETA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: BPP2_BOTNU
Sequence: EEGGRPPPPI
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent.
What are the official names of this protein?
Bradykinin-potentiating peptide 2, BPP-2, BPP-II.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_PROMS
Sequence: MKKLSKRMAALSTKIEDRIYAPLEALSIIKENANAKFDETIEAHIRLGIDPKYTDQQLRTTVVLPHGTGQSIKIAVITSGENVSKAKAAGADLFGEEDLVESINKGNMEFDLLIATPDMMPKVAKLGRVLGPRGLMPNPKAGTVTNDIANAIKEFKAGKLEFRADKAGIVHVRFGKASFTKEALFDNLKTLQESIDKNKPSGAKGKYWKTFYVTSTMGPSVQLDINAVQDYQPEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ARC_RHOE4
Sequence: MSSTENPDSVAAAEELHALRVEAQVLRRQLAQSPEQVRELESKVDSLSIRNSKLMDTLKEARQQLIALREEVDRLGQPPSGYGVLLSVHEDKTVDVFTSGRKMRLTCSPNIDTDTLALGQTVRLNEALTIVEAGTYEQVGEISTLREVLDDGLRALVVGHADEERIVWLAAPLAAVFADPEADIIAYDADSPTRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVHYDDIGGLGRQIEQIRDAVELPFLHKDLFHEYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKIAEARGQDSKDAKSYFLNIKGPELLNKFVGETERHIRMIFQRAREKASEGTPVIVFFDEMDSIFRTRGSGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAESAQDIFSKYLVDGLPINADDLAEFGGDRTACLKAMIVRVVDRMYAESEENRFLEVTYANGDKEVLFFKDFNSGAMIQNIVDRAKKYAIKSVLDTGAPGLRVQHLFDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKNASASRAIDTESNTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: RL11_PARMW
Sequence: MAKKVTAVIKLALQAGKANPAPPVGPALGQHGVNIMMFCKEYNARTQDKAGFVIPVEISVYEDRSFTFITKTPPASVLITKAAKIEKGSGESAKGNVGSINRAQLEEIAKTKLPDLNCTSVESAMRIIEGTARNMGVSISD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL33_RHOPA
Sequence: MAKAVTIKIKLVSTADTGFYYVTKKNSRTMTDKMVKKKYDPVARKHVEFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33, RRP-L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DTD_BACFR
Sequence: MRVVIQRVSHASVTIDGHCKSAIQKGMMILVGIEETDSREDIDWLCKKIVNLRIFDDENGVMNKSILEDEGNILVISQFTLHASTKKGNRPSYIKAAKPEISIPLYEQFCKDLSCALGKEVKTGEFGADMKVELLNDGPVTICIDTKNKE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEEP_ECOLI
Sequence: MIQLFRVVISEQIIDNSEPVKCKRRTTLGKSLLFSRVLYREWWPATYCSRVSGYRDILPELDLVLWLIKADDRALSVDEYFWRHILQCGHQQVLFVVTQADKTEPCHEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCIASVARTVLRAVRDTVVSVARAVWNWIFF
What are the official names of this protein?
Putative uncharacterized protein YeeP.
What is the protein family that this protein belongs to?
To E.coli YfjP and YkfA.
Protein: SODM_STRAG
Sequence: MAIILPDLPYAYDALEPHIDAETMTLHHDKHHATYVANANAALEKHPEIGEDLEALLADVSQIPEDIRQAVINNGGGHLNHALFWELMSPEETQISQELSEDINATFGSFEDFKAAFTAAATGRFGSGWAWLVVNAEGKLEVLSTANQDTPIMEGKKPILGLDVWEHAYYLNYRNVRPNYIKAFFEIINWNKVNELYQAAKA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.