PharMolix/UniProtQA huggingface dataset:
Protein: KMT5A_BOVIN
Sequence: MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTNGENVFTGQSKIYTYMSPNKCSGMRSPLQEENSVAQYEVKCQGKPLAGIYRKRDEKRNSGNAIRSSMKAEEQKIKDARRGPLAPFPNQKSEAAEPPKTPTSSCDTPNAAAAKQGLKKPVRGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGEFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIEAGEELLYDYGDRSRASIEAYPWLKH
What is the function of this protein?
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins.  Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1).  H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression.  Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.  Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis.  Involved in chromosome condensation and proper cytokinesis.  Nucleosomes are preferred as substrate compared to free histones.  Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes.  Plays a negative role in TGF-beta response regulation and a positive role in cell migration.
What are the official names of this protein?
N-lysine methyltransferase KMT5A, H4-K20-HMTase KMT5A, Histone-lysine N-methyltransferase KMT5A, Lysine-specific methylase 5A, PR/SET domain-containing protein 07, PR-Set7, PR/SET07, SET domain-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Specifically localizes to mitotic chromosomes. Associates with silent chromatin on euchromatic arms. Colocalized with SIRT2 at mitotic foci. Associates with chromosomes during mitosis; association is increased in a H(2)O(2)- induced oxidative stress-dependent manner. Not associated with constitutive heterochromatin (By similarity).
Protein: YBJQ_ECOK1
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ECFA2_CALS4
Sequence: MPIKVENVSFIYNEGTPYATVALKDINFSIDDEEFVGIIGHTGSGKSTLIQQLNGLLKPSKGKIYINGIDITDKKVSLKDIRKQVGLVFQYPEYQLFEETVFKDIAFGPSNLGLSEEEVKERVYEAMEIVGISKELADKSPFELSGGQKRRVAIAGILAMRPKILILDEPTAGLDPKGKQEILNKIKEIHDKYKMITILVSHNMEDIARIADKIIVMNRGKIELIGTPREVFREAERLEKIGLSVPQITSLARELRKRGVPIPPDVLTIEEAKEHILRYLRGTKNV
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RBX1_DICDI
Sequence: MADVEASSSASKTPKKKFEVKRWNAVALWIWDIVVDNCAICRNHIMDLCIECQANQASNTSEECTVAWGICNHAFHFHCISRWLKSRQVCPLDNRDWEFQKYGR
What is the function of this protein?
Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity).
What are the official names of this protein?
RING-box protein 1.
What is the protein family that this protein belongs to?
Belongs to the RING-box family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VSR_PVSP
Sequence: MKAERLEMLLLCVYRLGYILPVDVCIKIISVAQVSVQGRSTYSCKRRARSIGRCWRCYRVYPPVCNSKCDNRTCRPGISPNFKVVTFIRGWSN
What is the function of this protein?
Suppressor of viral-induced RNA silencing.  The potential mechanism of action is based on sequestering siRNAs (By similarity).
What are the official names of this protein?
RNA silencing suppressor, 10.7 kDa protein, Putative nucleic acid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the carlaviruses nucleic acid-binding protein family.
Protein: PTP22_STYPL
Sequence: WLMIVEQKCRVIVMLAKCFEAGKKKCQKYWPDSKETKTFGRVKVFNVEEVKYCGFLRRRFHIESVDEVITMEVFQYQYINWPDHSVPNTTSNLVRMHKYVIQCLEETGGDAPMVV
What are the official names of this protein?
Tyrosine-protein phosphatase 22.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: NANM_YERPP
Sequence: MTQLYPQYKKQLTTKIVLFSALSLLMMASLPNTYAEQYPDVPVPFKNGTGGKVENSLYVGLGSAGVSWFRLDTDKTGAGWQKVANFPGQPREQAVTVVLAGKLYVFGGVGKTNANDTQVRALDDAYRFDPQTNQWQQLATRAPRGLVGTVATTLDGSQAVLLGGVNKAIFDGYFTDLASAGSDEVRKSAVINAYFNQAPADYFYNRDVLIYDPQKNQWKSGGLLPFLGTAGSAISRMDNRLILINGEIKPGLRTAAVWQGLMQGNVLEWQPQPDLIGAETGSAQEGLAGAFSGISHKTVLVAGGANFPGAWKQFNRGHLYAHQGLEKQWHQQVYALVDNQWRIAGKLPQPLGYGVSIQGPDKVILIGGETTGGTATSAVTQLSWQGGKLHIE
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOB_AERS4
Sequence: MKYTLTRIDPDAPVERYPQEQSQTVDDPLAQDATRGIMMGRLEEVLQDTVNWGRKNSLWPYNFGISCCYVEMCTAFTSPHDVARFGAEVIRASPRQADFMVIAGTPFIKMAPVIQRLYEQLLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAFLQALMLLQDSIGKERRPLSWVVGDQGIYRPDMPAEKDRKRGERIKVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BIOY_RHOCB
Sequence: MERNVTLIGLFAALIVALGFVPAIPLGFGVPITLQSLGVMLAGAVLGSWRGALAVLLVQALVAIGLPVLAGGRGGLGIFVGPTAGFLIGWLPAAFVTGLIVERLRRVPVALAAGIGATLGGIIIMYALGILGFWLVKNAGLKPEDAPISLWAATAIMAPFIPGDLVKVVVTGLVARTIAQYRPSALLARG
What is the function of this protein?
Central protein that confers the ability to take up biotin on E. coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake.
What are the official names of this protein?
Biotin transporter BioY, Biotin ECF transporter S component BioY.
What is the protein family that this protein belongs to?
Belongs to the BioY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL10_XANCP
Sequence: MALNLSQKQEVVAELADIAAKAHSLIAAEYAGITVSQMTAMRKQARETGVFLKVVKNTLAVRAVEGTDFAVAADKLVGPLLYAFSMEEPGAAGRLIKEFAKGNDKLQAKVVSIGGELFPASHVDVLASLPTLDQALAMLARVLSEPAAMFARAVKAVGDKQGGGDEAAAPVAETAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: VDAC1_RAT
Sequence: MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVNGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETSKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQVDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane and also the plasma membrane (By similarity).  The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis (By similarity).  It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity).  The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:25628567).  Binds various signaling molecules, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity).  In depolarized mitochondria, acts downstream of PRKN and PINK1 to promote mitophagy or prevent apoptosis; polyubiquitination by PRKN promotes mitophagy, while monoubiquitination by PRKN decreases mitochondrial calcium influx which ultimately inhibits apoptosis (By similarity).  May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (By similarity).  May mediate ATP export from cells (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 1, VDAC-1, rVDAC1, Outer mitochondrial membrane protein porin 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: NADK_HELPS
Sequence: MKDSHQTIGVFVRPTHYQNPLFEKLERAKEWVLKLLEDEGFESFMIDGLDGAKDERLIEKAYAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKGFLQDLKQDKIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIQAYVGHTPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYDLKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_PSEA6
Sequence: MSMQDPIADMFTRVRNGQMASKVSVSMPSSKLRVAIAAVLKEEGYVSDFAVSGDVKPVLEVTLKYFEGKKVIESIERVSRPGLRIYKKKDELPKVLGGLGVAIVSTSKGVMTDRAARKAGMGGEIIGYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: KDSB_GRAFK
Sequence: MKEPSKNRIVAMIPARYKASRFPGKLMKDLNGKTVIARTYEAAVNTELFDEVYVVTDSNKIFDEIVNEGGQVIRSKKEHECGSDRIAEAVENMDVDIVVNVQGDEPFIDKNSLAKLLKVFEQEGAEEIDLTSLKTPLKDSDDITNPNNVKVITGKDDFALYFSRFPIPYRRDTSANVTYYKHIGIYAFRKSALMDFYRLPMLHLEAAEKIECIRYLEYGKKIKMVETSVKSVGIDTPEDLEKARKLLS
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAA_STRDO
Sequence: MLQKCKLEGIIICNEKRLLGAAKVKSGRTLSGALLGTAILASGAGQKALAEETSTTSTSGGDTAVVGTETGNPATNLPDKQDNPSSQAETSQAQARQKTGAMSVDVSTSELDEAAKSPQEAGVTVSQDATVNKGTVEPSDEANQKEPEIKDDYSKQAADIQKATEDYKASVAANQAETDRINQEIAAKKAQYEQDLAANKAEVERSLMRMRKPRPIYEAKLAQNQKDLAAIQQANSDSQAAYAAAKEAYDKEWARVQAANAAAKKAYEEALAANTAKNDQIKAEIEAIQQRSAKADYEAKLAQYEKDLAAAQAGNAANEADYQAKKAAYEQELARVQAANAAAKQAYEQALAANSAKNAQITAENEAIQQNAQAKADYEAKLAQYQKDLAAAQSGNAANEADYQEKLAAYEKELARVQAANAAAKQAYEQQVQQANAKNAEITEANRAIRERNAKAKTDYELKLSKYQEELAQYKKDLAEYPAKLQAYQDEQAAIKAALAELEKHKNEDGNLSEPSAQSLVYDLEPNAQVALVTDGKLLKASALDEAFSHDEKNYNNHLLQPDNLNVTYLEQADDVASSVELFGNFGDKAGWTTTVSNGAEVKFASVLLKRGQSATATYTNLKNSYYNGKKISKVVYKYTVDPDSKFQNPTGNVWLGIFTDPTLGVFASAYTGQNEKDTSIFIKNEFTFYDEDGNPIDFDNALLSVASLNREHNSIEMAKDYSGTFVKISGSSIGEKNGMIYATDTLNFKKGEGGSLHTMYTRASEPGSGWDSADAPNSWYGAGAVRMSGPNNYITLGATSATNVLSLAEMPQVPGKDNTAGKKPNIWYSLNGKIRAVNVPKVTKEKPTPPVEPTKPDEPTYEVEKELVDLPVEPKYEPEPTPPSKNPDQSIPEKPVEPTYEVEKELEPAPVEPSYEKEPTPPQSTPDQEEPEKPVEPSYQSLPTPPVEPVYETVPGPVSVPTVRYHYYKLAVQPGVTKEIKNQDDLDIDKTLVAKQSTVKFQLKTADLPAGRPETTSFVLMDPLPSGYQLNLEATKVASPGFEASYDAMTHTVTFTATAETLAALNQDLTKAVATIYPTVVGQVLNDGATYTNNFTLMVNDAYGIKSNIVRVTTPGKPNDPDNPSNNYITPHKVNKNENGVVIDGKSVLAGTTNYYELTWDLDQYKGDKSAKEIIQKGFFYVDDYPEEALDLRTDLIKLTDANGKAVTGVSVADYASLEAAPAAVQDMLKKANIIPKGAFQVFTADDPQAFYDAYVVTGTDLTIVTPMTVKAEMGKTGGSYENRAYQIDFGNGYESNLVVNNVPKINPEKDVTLTMDPADSTNVDGQTIALNQVFNYRLIGGIIPADHAEELFEYSFSDDYDQTGDQYTGQYKAFAKVDLTLKDGTIIKAGTDLTSYTEAQVDEANGQIVVTFKEDFLRSVSVDSAFQAEVYLQMKRIAVGTFANTYVNTVNGITYSSNTVRTSTPEPKQPSPVDPKTTTTVVFQPRQGKAYQPAPPAGAQLPATGDSSNAYLPLLGLVSLTAGFSC
What are the official names of this protein?
Cell surface antigen I/II, Surface protein antigen A.
What is the protein family that this protein belongs to?
Belongs to the antigen I/II family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: DNAA_STRPZ
Sequence: MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATIYLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQALNSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLGANFKQIDTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQGGKFYGVTGKEIKATKRTQNIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR1_BUCAI
Sequence: MKKNLFVTKRDGRKEKINLDKIHKVLNWASEGLDDVSVSQVELCSRIQFYNNITTINIHETIIKAAADLISQDTPDYQYMAARLAIFHLRKKAYGQFEPPKLYDHVKKMVDLEKYDENLLKNYSYKEFLQMNSFIDHWRDMNFSYAAVKQLEGKYLIQNRVNGKIYESAQFLYILISACLFSQYPKNVRMNYIHRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLNSINATTSSIVKYVSQRAGIGVNAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATIFYPIWHLEVESLLVLKNNRGIEENRVRHIDYAIQINKLMYQRMLSGDQITLFSPSDVPDLYKAFFSDQKKFKKIYLQYEKNKNIRKKTIKALDLFSLMMQERTSTGRIYVQNVDHCNLHSAFNPELSPIRQSNLCLEITLPTKSLNDVHDTDGEIALCTLSAFNLGKIKSLDDFKELSILSVRALDEILDYQNYPVLAAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAHNLTHKTFEAMQYYLLEASCELAKEKGACSLFNHTNYYLGKLPIDTYKKYIDDICNEPLHLDWNLLRSKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGFISIKVSKDGILRQVVPEYKKLRLQYELLWDIPNNTGYLQLAGIMQKFIDQSISVNTHYDPARFLNNKIPMKQLLYDLLLSYKLGLKTLYYQNTRDGSEDDQNITSKSITEDICESGSCIL
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: APOA5_PHOVI
Sequence: MVAVLTWALALLSAFATAQTQKGFWDYFSQSSGDKSKVARVQQQKLTWETTSLKDSLEQDLSNMDKFLEKLGPLSGQGREPPGLAHDPEGMRQQLQDELAEVRARLEPYMAEAHQQVGWNLEGLRRQLKPYTVELMEQVARRVQELQEQLRVVGEGTKAQLLGGVDEARGLLQELQTRVVQHTGRVRELFHPYAQRLVTGIGRHVQELHRSVAPHAAASSARLSRCVQTLSRKLTLKAEALHARIQQNLDQLREELSAFAGAGAGGAEEGANPDPQMLSQEVRQRLQAFRHDTFLQIADFTRAIDQETEEVQLQLAPPPPGHSAFAPEFLQADSSEARSKLQARLEDLWEDINDSLHDGGLSHLEEP
What is the function of this protein?
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL.  May also be associated with chylomicrons (By similarity).  Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity).  Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages (By similarity).  Binds heparin (By similarity).
What are the official names of this protein?
Apolipoprotein A-V, Apo-AV, ApoA-V, Apolipoprotein A5.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Early endosome. Late endosome. Golgi apparatus, trans-Golgi network. Note=In the presence of SORL1, internalized to early endosomes, sorted in a retrograde fashion to late endosomes, from which a portion is sent to lysosomes and degradation, another portion is sorted to the trans-Golgi network.
Protein: RECA_BACTN
Sequence: MASSEKLKALQATMEKIEKNFGKGSIMKMGDDSVEQVEVIPTGSIALNVALGVGGYPRGRIIEIYGPESSGKTTLAIHAIAEAQKAGGIAAFIDAEHAFDRFYAAKLGVDVDNLWISQPDNGEQALEIAEQLIRSSAIDIIVIDSVAALTPKAEIEGDMGDNKVGLQARLMSQALRKLTGTVSKTRTTCIFINQLREKIGVMFGNPETTTGGNALKFYASVRIDIRGSQPIKDGEEVLGKLTKVKVVKNKVAPPFRKAEFDIMFGEGISHSGEIIDLGAELGIIKKSGSWYSYNDTKLGQGRDAAKVCIKDNPELAEELEGLIFEALNKK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_TRIL1
Sequence: MIQMQTILDVADNSGAKKLFCIKVLGGSKRKYAGVGDIVVCSVREALPNSKVKKGDVVKAVIVRTAKELGRPDGSYIRFDNNSGVVINNAKEPVGTRIFGPVARELRAKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL32_PSEA6
Sequence: MAVQKNRKTRSKRGMRRSHDALGTATMSVDSTSGETHVRHHVTADGYYKGKKVLSL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: YBJQ_ECOUT
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ENO_BURA4
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWEGWKLLTERLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RAB14_PONAB
Sequence: MATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKPSAPQGGRLTSEPQPQREGCGC
What is the function of this protein?
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development.  Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.  May act by modulating the kinesin KIF16B-cargo association to endosomes.  Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion (By similarity).
What are the official names of this protein?
Ras-related protein Rab-14.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Note=Recruited to recycling endosomes by DENND6A. Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: CLPP_PSE14
Sequence: MSRNSYIQQNSDIQAAGGLVPMVIEQSARGERAYDIYSRLLKERVIFMVGPVEDYMANLIAAQLLFLEAENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTICIGQACSMGAFLLAGGAEGKRHCLPNSRMMIHQPLGGFQGQASDIDIHAKEILHIRHRLNSLLAHHTGQSLETIERDTERDNFMSAERAAEYGLIDSVINKRQMPA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPRH_MYCTU
Sequence: MACLGRPGCRGWAGASLVLVVVLALAACTESVAGRAMRATDRSSGLPTSAKPARARDLLLQDGDRAPFGQVTQSRVGDSYFTSAVPPECSAALLFKGSPLRPDGSSDHAEAAYNVTGPLPYAESVDVYTNVLNVHDVVWNGFRDVSHCRGDAVGVSRAGRSTPMRLRYFATLSDGVLVWTMSNPRWTCDYGLAVVPHAVLVLSACGFKPGFPMAEWASKRRAQLDSQV
What are the official names of this protein?
Putative lipoprotein LprH.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.