PharMolix/UniProtQA huggingface dataset:
Protein: PTPN3_MDBVW
Sequence: MYAERSSNLSIHEFWRRKSSKYMKTIKSEHLFVNHTCWYEETPETKKRNRXHRHRSSVKSIQSLEPSVNGSDSFYASYVDGYDLKRKFIVVETLTSEKKSRNYWKLIWETNCRVIVRFDINDWKNCQYWLHNHISDYTEGEFNVWKKKTISHNYYTEILLTVANKKNGKSKQITHYEYHEHPDGKLPIESARFIFFLKMVNKSQENYNISASSSNKCARTPIVVHSVGRYERAISFCALDICLNQIRETKSVSVPSVLLKIKGQTQLDFFSFEEYLIINKILLHSKWALELKTEDDGKTSFFRSRVRKYCLIFKRASVF
What are the official names of this protein?
Tyrosine phosphatase-like protein N3, PTP-N3.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: PYRG_DICDI
Sequence: MKYIVVTGGVLSGIGKGIIASSTAMILKSMGLRVTSIKIDPYLNIDAGTMSPFEHGEVFVLDDGGEVDLDLGNYERFLDVNLGKDNNITTGKIYNLVIEKERKGQYLGKTVQVVPHITEEIQNWIERVAHLPVDGDKGTPDVCVIELGGTVGDIESMPFTEALRQFQFRVGVENFCLMHVSLVPVLGVVGEQKTKPSQQSIRELRSLGLSPDFCLCRSTQPLTEETKKKISLFCHVAPDNVIGVHDVSNIYRVPILLNQQNLPNLVLRRLQLNPKVDLSKTSPSESTPYWMASWKGLADRMDKITNESLNPIRIAMVGKYTGLTDAYLSVIKALDHASMAIERKMVIDWVEASNLETQNSSTAEYKKSWEMLRGAHGILVPGGFGDRGIEGMILTANYARTSGKPFLGICLGLQIAVIEYARNVMGWENANSEEFSASGSGKNVVVFMPEVSKTHMGGTMRLGSRDTIFTDVDNKISKLYNVDKVGQAVEERHRHRYEVNPEVVDEIHAKGLHFVGKDTTGVRMEIVELKDHDYYVACQFHPEFKSRPQRPSPPFIGLLNASLERLKKM
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
What are the official names of this protein?
CTP synthase, CTP synthetase, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: OXLA_SIGCA
Sequence: MDLHRAPWKSSAAAAVLLLALFSGAAASSVEKNLAACLRDNDYDQLLQTVQDGLPHINTSNHVVIVGAGVAGLTAAKLLQDAGHRVTIVEANSRIGGRVETYRNKEEGWYADLGAMRIPSDHSIFRWFAKTLGVKLNPFIMDDHNTFYFVNGLLKRTYTVEANPDILNYKVRSSEKGKSANTLFQDALQKVKDEVEAHGCRAALMKYDKYSAKEYLKEVAGLSSEALRMIGDLLNEQSLMYTALSEMIYDQADVNDNVQYDEVTGGTDLFPRAFLSVLDVPILLNSKVQRIRRSRDGVTVSFKESQRSSLTDLHADMVLVTTTAKAALYMDFEPSLSIRKMEALRAVHYDSSTKIILTFSSRFWEEDGIRGGKSITDRPSRYIYYPSHTFPANSSVGVLLASYTWSDDSLLLQAASDEELKEMALRDLVKIHGERVRALCTGVVVKKWSLDPYSFGAFALFTPYQHLEYAKELFRSEGRVHFAGEHTAFPHAWMESAMKSAIRAATNINKQTLLNEGMNECPAPDEL
What is the function of this protein?
Inhibits the growth of both Gram-negative and Gram-positive bacteria.  Displays strong antibacterial activity towards V. cholerae and E. tarda.  Causes deformation of the surface of S. aureus and the formation of pores on the surface of E. coli.  Strong antiparasitic activity is seen towards C. irritans, T. brucei and I. multifiliis.  Cilia of treated theronts are lost and the macronucleus swells, inducing cell membrane rupture and efflux of the cytoplasm.
What are the official names of this protein?
L-amino-acid oxidase, Antiparasitic protein, APP, Serum L-amino-acid oxidase, SR-LAAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_PORGI
Sequence: MLTGLFFGSFNPMHIGHLALANYLTEYTPIGQLWFVPSPLNPLKNTQELLPYDLRCELIEQAIRKDIRFQVLRIEELLPSPHYTIRTLRALSMLYPHHRFALLIGADNWQSFDRWKDHHRLMAKYELIIYPRFGYEVDDTTLPTGCRYIHDAPRIEISSTQIRTSILEGKDLRYWLPLPESQDVIASALQSCLSPKR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MDH_SALMU
Sequence: IGQALALLLKNQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDVTPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKDVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQHSLDA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RHDF1_RAT
Sequence: MSEARRDSTSSLQRKKPPWLKLDIPAVVPPAAEEPSFLQPLRRQAFLRSVSMPAETARVPSPHHEPRRLALQRQTSITQTIRRGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKPQVIRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRMADDTADGLSAPHTPVTPGAASLCSFSSSRSGFNRLPRRRKRESVAKMSFRAAAALVKGRSIRDGTLRRGQRRSFTPASFLEEDMVDFPDELDTSFFAREGVLHEELSTYPDEVFESPSEAALKDWEKAPDQADLTGGALDRSELERSHLMLPLERGWRKQKEGGTLAPQPKVRLRQEVVSAAGPRRGQRIAVPVRKLFAREKRPYGLGMVGRLTNRTYRKRIDSYVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRKRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHNFILAAREREKHSACCVRNDRSGCVQTSKEECSSTLAVWVKWPVHPSAPDLAGNKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGRPCCIGTKGRCEITSREYCDFMKGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSVCFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFAFGLLPWIDNFAHISGFVSGLFLSFAFLPYISFGKFDLYRKRCQIIIFQAVFLGLLAGLVVLFYFYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH
What is the function of this protein?
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation.  Does not exhibit any protease activity on its own.
What are the official names of this protein?
Inactive rhomboid protein 1, iRhom1, Rhomboid family member 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly localized in the endoplasmic reticulum membrane.
Protein: HOX6_ORYSJ
Sequence: MDGEEDSEWMMMDVGGKGGKGGGGGGAADRKKRFSEEQIKSLESMFATQTKLEPRQKLQLARELGLQPRQVAIWFQNKRARWKSKQLEREYSALRDDYDALLCSYESLKKEKLALIKQLEKLAEMLQEPRGKYGDNAGDDARSGGVAGMKKEEFVGAGGAATLYSSAEGGGTTTTTTAKLMPHFGSDDVDAGLFLRPSSQHHPPPPHAGAGFTSSEPAADHQSFNFHSSWPSSTEQTCSSTPWWEFESE
What is the function of this protein?
Probable transcription factor that binds to the DNA sequence 5'-CAAT[AT]ATTG-3'.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX6, HD-ZIP protein HOX6, Homeodomain transcription factor HOX6, OsHox6.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI_TREPS
Sequence: MNWRNLDECAAYARLQAIRAPSLKTVLCGPEGIERVRRYCTDAGAGLRYHYAAKTVNEEILTALAALADEQELVAKYDALRAGAQINTGEKRKVLHHLTRLGVQGSSLASLPCEVRDMHAFYTKEYERVCAFARQVHEGGLRTSRGAPFTDVVQIGIGGSDLGPRALYLALEGWAQRHQAVKMRTHFISNVDPDDAALVLSKLPLETTLFILVSKSGTTLETLSNELFVAHVLRQAGLEPHTQFVAVTSETSPLANNPQYLASFYMDDFIGGRYSSSSVCGAVVLTLAFGPQVFGHFLSGAAEADRAAQEQDIRRNAALLDALIGVYERTILGYEHTAVLPYSQALARFPAHLQQLDMESNGKSVNRFGIPITYKTGPVIFGEPGTNGQHSFYQHLHQGTSVVPLQFIAFQHSQLGQDPIIRGSTGQQKLLANVVAQIVAFARGKEHADANKTFSGERPSSLLYAKALTPQTLGALLAHFENKIMFQGFAWNLNSFDQEGVQLGKTLAQHILAGEVEGVLRAYADLFDLAHAPTC
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_SHESM
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQVCGGLSDREMDAQVLDSMDLERERGITIKAQSVTLEYKAKNGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALDMNLDVVPILNKIDLPQADPERVAAEIEDIVGIDAMNAVRCSAKTGVGIDEVLEVIVEQIPPPEGDPEAPLQALIIDSWFDSYLGVVSLVRIKNGVLKKGDKFKVMSTGQNHTADRVGIFTPKQTDKTELKTGEVGFVIAGIKEIHGAPVGDTLTLAKHGAEKPLPGFKKVKPQVYAGVFPISTDEYENFRDALNKLSLNDASLFFEPESSSALGFGFRIGYLGLLHMEIIQERLEREYDLDLITTAPTVVYEVLLTSGETVYVDNPADLPAINNIEEMREPIVEANILVPKEYLGNVITLCIEKRGTQVNMVYHGNQVAVTYHLPMAEVVMDFFDRLKSTSRGYASLEYNFIRFDPADMVRLDILINGDRVDALAMIIHRSNIRHRGLALVEKMKELIPRQMFDIAIQAAVGSQIIARSTVKALRKDVTAKCYGGDVSRKKKLLNKQKEGKKRMKQVGNVEVPQEAFLAVLKLNE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: JUPI2_HUMAN
Sequence: MFQVPDSEGGRAGSRAMKPPGGESSNLFGSPEEATPSSRPNRMASNIFGPTEEPQNIPKRTNPPGGKGSGIFDESTPVQTRQHLNPPGGKTSDIFGSPVTATSRLAHPNKPKDHVFLCEGEEPKSDLKAARSIPAGAEPGEKGSARKAGPAKEQEPMPTVDSHEPRLGPRPRSHNKVLNPPGGKSSISFY
What is the function of this protein?
(Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2.
What are the official names of this protein?
Jupiter microtubule associated homolog 2, Hematological and neurological expressed 1-like protein, HN1-like protein.
What is the protein family that this protein belongs to?
Belongs to the JUPITER family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with type 1 ryanodine receptor (RYR1).
Protein: US02_HCMVM
Sequence: MNNLWKAWVGLWTSMGPLIRLPDGITKAGEDALRPWKSTAKHPWFEIEDNRCYIDNGKLFARGSIVGNMSRFVFDPKADYGGVGENLYVHADDVEFVPGESLKWNVRNLDVMPIFETLALRLVLQGDVIWLRCVPELRVDYTSSAYMWNMQYGMVRKSYTHVAWTIVFYSINITLLVLFIVYVTVDCNLSMMWMRFFVC
What is the function of this protein?
Participates in the inhibition of the host immune response.  Early protein that redirects newly synthesized major histocompatibility complex (MHC) class I heavy chains via the SEC61 translocon to the cytosol where they undergo proteasome-dependent destruction.  In consequence, infected cells are masked for immune recognition by cytotoxic T lymphocytes.  Seems so far to be specific for HLA-A, HLA-B, and HFE loci products.  Does not interact with HLA-DR or HLA-DM.
What are the official names of this protein?
Unique short US2 glycoprotein, Protein HQLF2, gpUS2.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US2 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: XRCC1_HUMAN
Sequence: MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPVTASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPRGEGTEPRRPRAGPEELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSQRYLMAGPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPPDLPVPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA
What is the function of this protein?
Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (PubMed:11163244, PubMed:28002403).  Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity (PubMed:34102106, PubMed:34811483, PubMed:28002403).  Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity (PubMed:14500814, PubMed:34102106, PubMed:34811483).
What are the official names of this protein?
DNA repair protein XRCC1, X-ray repair cross-complementing protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Moves from the nucleoli to the global nuclear chromatin upon DNA damage.
Protein: RECR_SYNP6
Sequence: MSVYTRPLARLIEHLQKLPGVGPKTAQRLALHLIQRPEAEIAAFAEALLAAKQQVGHCQRCFHLSSEDLCNICRDPKRDAQTICVVADPRDVIALEKTREYKGLYHVLGGLISPMDGIGPEQLTVQALVRRVAQEQTQEVIMAISPSVEGETTTLYVGQLLKPFTRVTRIAFGLPMGGDLEYADEVTLARALEGRRDLT
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NANM_SALNS
Sequence: MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPDAGTAGSSSVMENNFLMLINGELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKKWRDEVYGLVNGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ESTB_SCHGA
Sequence: NPVVRITNGAIRGQN
What are the official names of this protein?
Esterase 56 kDa subunit, Carboxylic-ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_EXIS2
Sequence: MRLDSVRLSHYRNYESLELSFSEKTNVLIGENAQGKTNLLEAIYVLALAKSHRTTHDKELIQWDAETARVEGRIHKRRGSHSQEIAISSRGKKAKLNHLEQRRLSDYVGALNIVLFAPEDLHIVKGSPQIRRRFLDMEIGQVSPVYLHELSQYLKVLKQRNALLKQLSMKGGDETFLDVLTEQMITLAVKIVQRRHHFIAQLEKWARPIHEGISRGQEQLVLIYRSDTFSNDLLDVEGMTASYMQKFGKMKTNEIRRGVTLFGPHRDDFEMEVNGRNVQTYGSQGQQRTAALSLKLAEIELIHEEVGEYPLLLLDDVLSELDDHRQTHLLDTMQQKVQTILTTTSVDGIAHETIKQAKLFHVKQGAVILEETSYKEIVGEKTDE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_SHIFL
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PNP_PARPJ
Sequence: MTMFNKIVKEFQWGQHKVRLETGEIARQASGAVIVDVEDTVVLATVVGAKTAKPGQDFFPLTVDYLEKTYAAGKIPGGFFRREGRPSEGETLISRLIDRPLRPLFPEGFYNEVQVVIHVLSLNPEIPADIPALIGASAALAVSGLPFNGPVGAARVAYINNEYVLNPTRPQMKESALDLIVAGTERAVLMVESEAQQLSEEVMLGGVVFGHEQMQIAIDAIHDLVREGGKPEWDWQPAAKNEPLIARVTELAQADLLAAYQLRDKQARSAKLKEVYAATSKKLEEDAAAGGTVAADKATVGNVLFDIEAKIVRTQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQAMVVATLGTKGDEQNIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALAACLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTEQGVTALQMDIKIQGITKEIMQVALAQAKEGRMHILSKMTSAVSGANTVLSDYAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTSSEGMAEAKKRIENITLEVEVGQVYEGTVLKLLDFGAIVNILPGKDGLLHISEIANERIKDINDYLKDGQQVKVKVIQTDEKGRVRLSAKALLNEGANGASGAPQGEPTPQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_YERPA
Sequence: MLTPIIRKFQYGQHTVTIETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQSFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLTSRLIDRPIRPLFPDSFLNEVQVIATVVSVNPQINPDIVALIGASAALSLSGIPFNGPIGAARVGFINDQYVLNPTTDELKESRLDLVVAGTAGAVLMVESEADILSEEQMLGAVVFGHEQQQVVIENINALVAEAGKPKWDWQAEPVNEALHARVAELAEARLGDAYRITEKQERYTQVDAIKADVTEALLAQDDTLDAAEIQDILASVEKNVVRSRVLRGEPRIDGREKDMIRGLDVRTGILPRTHGSALFTRGETQALVTATLGTARDAQNIDELMGERTDSFLLHYNFPPYCVGETGMVGSPKRREIGHGRLAKRGVLAVMPSASEFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGSRDGVTALQMDIKIEGITREIMQVALNQAKGARLHILGVMEQAISTPRGDISEFAPRIYTMKINPEKIKDVIGKGGSVIRALTDETGTTIEIEDDGTIKIAATDGDKAKHAIRRIEEITAEIEVGRIYAGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQDVPVKVMEVDRQGRIRLSIKEATTPDAEAPEAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_VESOH
Sequence: MSMSDPIADMLTRIRNAQLVKKKEVNVPSSNLKFAIAGVMQQEGYIESFSVNGVVASKILKIKLKYYDNKPVIEKLKRISKPSLRVYVSNSKIPSVMNGLGIVIVSTPKGVMTGQVALDQNVGGEVLCSIY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: LPXA_SULNB
Sequence: MSAIHPTAIVEDGAILGENVSVGPFAYIGAKVSIDDGTSVASHAVIEGRTSIGKNNRIFSHSAIGTIPQDLKYAGEDVELIIGDNNNIREFTLLNPGTKGGGSVTKIGNGNLLMGYVHLGHDVILGDNCILANGATLAGHVELGNNVVIGGLTPVHQFVHVGDFAMIGGASALAQDIPPYCLAEGNRATLRGLNLTGLRRHIPREEINALKSAYRELFEEGKALQDVAQRLFEESSSEKVKNLCKFIKTSKRGIPFTRKS
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I40A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMISGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVGGKWMRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEREGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACNSAAFEDLRVSSFIRGTKVVPRGRLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDKTTIMAAFTGNAEGRTSDMRAEIIRMMENARPEEVSFQGRGVFELSDERAANPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: IDI2_THEVB
Sequence: MQSNLGTLLVNSPIEQRKAEHLKLCLQGDVNHQEITTGFEKYRFRHCALPELDFAEIDLRVEFLGWRLAAPLLISSMTGGTPQAGEINRRLARVAQQKGIVMGVGSQRVLLEHPEVATTFAIRREAPTIPLLANLGAVQLNYGCGVSECQKIVDLLEANALILHLNPLQEAVQTGGDRNFKGLLTKIGVLCRALPVPVIVKEVGNGISAEVAKQLVDVGVAAIDVAGAGGTSWAKVEAARAQDASQRYLGDAFAEWGIPTAHCLEQVHTALPDTPLIASGGLKDGIDVAKALALGAGLAGLARPFLQAAHQSEEALAQRIDLLLEELKTVLFCTGSATPQALYQRRCLERI
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_RHORT
Sequence: MSEETLSFQAEVSKLLDIVVHSLYSDRKIFLRELISNASDACDKLRYEGLTQPALLEGDGAFRIRLSIDAEAGTLTIADNGIGMNRHELIENLGTIARSGTQAFAEALKAKSQAASGDVSLIGQFGVGFYSAFMVADKVEVVTRRAGEAQGWRWSSDGKGSFSVSEVEGAGRGAAITLHLREDARDFLDEHRLREIVKTYSDHIAIPVDYAGKEGEPERLNEASALWTRPRDQITDEQYAEFYHHVAHGFETPWHTLHYRAEGKLEYTALLFVPGQQPFDLFTQDRKPRVKLYVNRVFITDDCEELLPSYLRFVRGVVDSSDLPLNVSREMLQDDPRLRKIKGGLTKRLIDDLAKRARDDESAYLTFWENFGAVLKEGIYEDFERKEDLVALARFRTTASDTPVSLETVIGRMKEGQSALYYITGDDATALARSPQVEGFVARGVEVLLLTDPIDEFWVSAVPKVGDTALKAVAQGSADLERLALIDGKQPPDDAEHAPAETAKMDALIAAMKAALGTAVADVRVSARLTDSPVCLVAKEGAMSLHLQKLLRQANQGSELSGDRVLEINPRHALVKTLAERAATGGSVDEAALLLMDQARILEGEAPADAIAFARRLTEVMGKGLI
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.