PharMolix/UniProtQA huggingface dataset:
Protein: FLXL4_ARATH
Sequence: MSSRERIGSNHHSRVSQGMSTSGSSSSRHHDTISSTSDPRHLRDHQISLSDILENKIAVQAAEIDRLSNDNRKLASSYVALKEDLTVADREVQGLRAHIRKTETDHEIQIRSTLEKIAKMEGMVKNRENIRREVQSAHIEAHRLAREREELASKVKLGMKDLKKVCLEAESLEASSQELERLKEEHQRLRKEFEEEKSGNVEKLAQLKGMERKIIGAVKAIEKLRSEISTARNKAVEN
What is the function of this protein?
Involved in FLC activation and flowering time control, but has no transcriptional activation activity.  Probably part of the FRI-C complex, but is not redundant with FLX.
What are the official names of this protein?
Protein FLX-like 4, AtFLXL4.
What is the protein family that this protein belongs to?
Belongs to the FLX family.
Protein: POL_FIVPE
Sequence: KEFGKLEGGASCSPSESNAASSNAICTSNGGETIGFVNYNKVGTTTTLEKRPEILIFVNGYPIKFLLDTGADITILNRRDFQVKNSIENGRQNMIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLGRDNMIKFNIRLVMAQISDKIPVVKVKMKDPNKGPQIKQWPLTNEKIEALTEIVERLEKEGKVKRADSNNPWNTPVFAIKKKSGKWRMLIDFRELNKLTEKGAEVQLGLPHPAGLQIKKQVTVLDIGDAYFTIPLDPDYAPYTAFTLPRKNNAGPGRRFVWCSLPQGWILSPLIYQSTLDNIIQPFIRQNPQLDIYQYMDDIYIGSNLSKKEHKEKVEELRKLLLWWGFETPEDKLQEEPPYTWMGYELHPLTWTIQQKQLDIPEQPTLNELQKLAGKINWASQAIPDLSIKALTNMMRGNQNLNSTRQWTKEARLEVQKAKKAIEEQVQLGYYDPSKELYAKLSLVGPHQISYQVYQKDPEKILWYGKMSRQKKKAENTCDIALRACYKIREESIIRIGKEPRYEIPTSREAWESNLINSPYLKAPPPEVEYIHAALNIKRALSMIKDAPIPGAETWYIDGGRKLGKAAKAAYWTDTGKWRVMDLEGSNQKAEIQALLLALKAGSEEMNIITDSQYVINIILQQPDMMEGIWQEVLEELEKKTAIFIDWVPGHKGIPGNEEVDKLCQTMMIIEGDGILDKRSEDAGYDLLAAKEIHLLPGEVKVIPTGVKLMLPKGYWGLIIGKSSIGSKGLDVLGGVIDEGYRGEIGVIMINVSRKSITLMERQKIAQLIILPCKHEVLEQGKVVMDSERGDNGYGSTGVFSSWVDRIEEAEINHEKFHSDPQYLRTEFNLPKMVAEEIRRKCPVCRIIGEQVGGQLKIGPGIWQMDCTHFDGKIILVGIHVESGYIWAQIISQETADCTVKAVLQLLSAHNVTELQTDNGPNFKNQKMEGVLNYMGVKHKFGIPGNPQSQALVENVNHTLKVWIQKFLPETTSLDNALSLAVHSLNFKRRGRIGGMAPYELLAQQESLRIQDYFSAIPQKLQAQWIYYKDQKDKKWKGPMRVEYWGQGSVLLKDEEKGYFLIPRRHIRRVPEPCALPEGDE
What is the function of this protein?
During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme.  RNase H activity is associated with the reverse transcriptase.
What are the official names of this protein?
Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
Protein: ACTG_EMENI
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRVDMAGRDLTDYLMKILAERGYTFSTTAEREIVRDIKEKLCYVALDFEQEIQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHVTTFNSIMKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, gamma.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DOT1_ASPOR
Sequence: MVLARFANESTSYNRYNLVVPRDKDDFRPIDDIFQVIETVSQNYIPEDEADYFDNESTGIKRRLRRALAHASEAEFRNVVTDYNEAIERLRRDGSIAQKLDSTHRLNLPLVERILTQIYSRTVSPRVESLRQYENGTDNVYGELLPRFISTIFKETGLKSGQVFVDLGSGVGNVVLQAALEIGCESWGCEMMQNACELAELQQTEFRARCRLWGIAPGKTHLVRGDFLKEQSIIDVLKRADVILINNQAFTPQLNNELINHFLDMKEGCQIVSLKSFVPAAHKIQSRNLNSPINLLKVKQREYWSNSVSWTDVGGTYFIATKDSSRLRAFAESMG
What is the function of this protein?
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3.  This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks.  Nucleosomes are preferred as substrate compared to free histone.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone H3-K79 methyltransferase, H3-K79-HMTase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOA_TRIEI
Sequence: MAQFHYECVESKTDKDRSQYGKFIIEPLARGQGTTVGNALRRVLLSNLEGTAITSVRIAGVNHEFATIKGVREDVLEILLNMKEVVLKSYSEQPQIGRLRVEGPATVTADRFDVPSEVEVIDRSQYIATLSPGSILEMEFRIEKGTGYKAVDRTRDDVATLDFLQIDAIFMPVRKVNYTIEDAHIGSSLEQDRLIMDIWTNGSYTPQDALSNAAGILMSLFEPLKDITNMADIPSGETTDPTSQIPIEELQLSVRAYNCLKRAQINSVADLLDYSQEDLLEIKNFGQKSAEEVIEALQKRLGITLPQEKVAKAT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HSE1_ASPFU
Sequence: MFRAQQNAFDDAVAKATDENLTSENWEYILDVCDKVAAEESGAKDAVAAMIKRLAHRNANVQLYTLELANALAQNCGPKIHRELASRSFTDALLRLANDRMFANNPDFGIMEQAYMKLKTQNPNLQPPSKPGKREITEADRQKEEEELQMALALSIREKPSAAPEPKAEPSTSVSEPASQTQTATSQAVPPGTSAATVSRVRALFDFQPSEPGELQFRKGDIIAVLESVYKDWWKGSLRGQTGIFPLNYVEKLPDPTVEELQREAQMEAEVFGQIKNVEKLLTLLSTRSSELNVQDNEEITSLYHSTLSIRPKLIELIGKYSQKKDEFTQLNEKFIKARRDYESLLEASMAHPAQPQYGRPGQAPYGYPGPAAPLGYPQGPPQSDPQRYFSPRPQDQTHMYPPTSHSPDPRGRTPPAGPSFPQHQQPPPDSYQPVHHRPESTYDNPQELGTSVYDSPVEHPSSSQRLPYPPSGAQVPPGVHQQFQHQQQEYPPSGYPPEDASKPPAAGFALQPPQQTLQQPPYPTAPGAHQPTPSHQPPPVPSTASKPTPYPSLTPGTPSGGEYQAYNPSQAGAANSNPNSYYR
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein hse1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BGLO_EMENI
Sequence: MTVLAPWALWEKTKDVMVLEQQYQSMCTWIAAIPENMKRHRHLCDPVVLQFAVAVRESNPWAVMTAYHKINGVHCSEDPRLIRDIPRSEWKYDGLVLCDWWGIYSTSELINAGMDLEMPGPTDWRCKILAWATRSRKVSIETIDSSVRRVLKLVNRVLAAQSEPVKDSDTEKNRALLRETTAVPVVLLKKNEANVLPLVKDSKTRYALIGDHWKNPAVAGDDSSEVTPYYVSTPYSAFVEAVGEDSFICAMGCYSHKFAPLLYSTITQPGSDAHGMLLEFFNKDPNGSSDAELLYTTTTEKTDLKFADSLPPDTVPEYTSSGSAPSRGSRWGCAGWIREAVEIARQVDIPVILTGLSADYEYEGIDRKSLGLPGRVDELIERVTEANPKTIIITEAGTATTMPWADKTPTVIHSWFGRQETGHGIVDILFGDVNPSGRLPLTFPRNLEVPPVYESDPKHIMTISVSLKNTGQCPGAEIVQVYVKDVSSSVQRPRKELKSFKKVHLAPGENMKIEVTS
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase O, Beta-D-glucoside glucohydrolase O, Cellobiase O, Gentiobiase O.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YAAA_SHISS
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNSQHLIHEARKLTPPQISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CRVPA_NOTSC
Sequence: SNKKDYQKEIVDKHNALRRSVK
What are the official names of this protein?
Cysteine-rich venom protein notescatin, CRVP, Notescatin-a, Notescatin-b.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECO_GLUDA
Sequence: MEWEAPALVLSASPYGESSAIVHLLTEDLGLVHGLARGGTARANRALWQPGNLIRASWRGRLPDQLGNLSGELVHGSAARLMSAPLALAMLASACAVADGTLPEREPHPRIFHLLTRFFSLLSLDPDMAGWGGMAALLRWEACLLGDLGYGMDLSACAVTGGSAELAWVSPRTGRAVSDAAAGEWRPRLLRLPPLFLDESDPGTVQDWRDGLRLTGHFLARDAFGQRHRPLPPARLRLVDMIDALQPGALHPDD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: JPH3_MOUSE
Sequence: MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQMSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTSTPPPAPASRTKMAHFSRQVSVDEERSGDIQMLLEGRGGDYARNSWGEEKAGASRGIRSGALRSGQPTEDFRTRGSGHKQPGNPKPRERRTESPTTFSWTSHHRAGNPCSGGPKLLEPDEEQLSNYKLEMKPLLRMDACPQDTHPQRRRHSRGAGGDRGFGLQRLRSKSQNKENLRPASSAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI
What is the function of this protein?
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells.  Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.  JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
What are the official names of this protein?
Junctophilin-3, JP-3, Junctophilin type 3.
What is the protein family that this protein belongs to?
Belongs to the junctophilin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N- terminal part associates with the plasma membrane.
Protein: FKH2_SCHPO
Sequence: MTVRRLESKSEHISDDEERKEQLDYKKQMDVDTDRNIVLNGRLESQIAKLSVPPHEMRVVDDYSNSKNAERHSGEIQAYAKFAGSTWTYYVKKIRIILGREPANPSPKGKNEDLEVIDMNFGPSKVVSRKHAVVEYDLDDQTWNCSVYGRNGIKVDGKLFKNGETVKLTSGSILEVAGLQMMFVLPNAAEQKQTDESTIKEDAIKSEISAAVNDAAEYGDNKKPPYSYSVMIAQAILSSSECMMTLSNIYSWISTHYPYYRTTKSGWQNSIRHNLSLNKAFRKVPRKSGEQGKGMKWSIVPEFREEFIAKTRKTPRKRSPSSPVPLLAKKREGSPSLPIPILPKMKDTSIPAAEPASSTTSARDQTPSTPKDVGSPSTAETSAEEKQMETYKTPTHAALSDIISTHDYALDANSASQTKKAAFGSPIGSSTYPTSSPAPFWKYVAVPNPHDWPQVGSYDTISPYRNPVNSHLIYSQIQQSSPKKIDEQLHDLQGVDLVNGFEGISSWRESMVNKLRSSVSDSPTMNLANSNSKSSPVAVQRVSTLPQASANKQAKEMESKMSNSPTQKSKTEENNQAVRAILDASATMEKQYDLHRLPTPTSQTESASVPQIANPPNSQNLVKEKSPQQYIQVPQSNVKSSA
What is the function of this protein?
Required for promoter sequence element PCB-driven, M-phase-specific transcription.  Acts as a transcriptional activator with a role in the regulation of mitosis.  Binds, cooperatively with mcm1, the CLB cluster regulatory elements throughout the cell cycle.  Regulates the periodic transcription of cdc15 and spo12.  Required for the correct timing, positioning and contraction of the division septum.
What are the official names of this protein?
Fork head protein homolog 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CIAO1_VANPO
Sequence: MSLNLVKALKLHNEKIWDIDCYKGLLATASTDRRIKIVNIGDIGDGLVSDDGRLLDELDDSSHKKTVRSVAWRPHSTILAAGSFDSTVSIWAKDENDGDADGDGGVDDPSSFSMELLAVIEGHENEVKSVAWSKDGYFLATCSRDKSVWIWESDEMGEEYECISVLQEHSQDVKHVVWHPFKDILASSSYDDTIRIWKEYDDDWEAAAVLKGHEGTVWGSDFEKNVNTDIVRLCSGSDDTTVKIWRCVSNESIEEDWICEATLPNVHGKPVYSVSWSEDGLIASAGSDGMLVIYKENKDNVWEVVAKHEHSHSIYEINVVKWIKLNNGKSYLATAGDDGYVNIWAYN
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: YIDC_CAUSK
Sequence: MQNDSNKNTLMFLVCAFAILIGYQFLVMGPQQKQREAELRAKKAAEAQVAVQPGMTIGADGTPQPLKLSRDEAKAQSPRIAVDTPALSGSIALKGARIDDLWLKRYTQTADKNSPPVELFRPEGAEHAWFADFGWAGIAGMTGLPTPQTVWTAAPGQVLRPTTPVVLTYDNGQGLVFTRTISVDADAMFTVADTVRNQGGAAVALAPYASVQRQGIPTEGPHGLGKTQIVYEGGIGVLGGIDGVEGGKYILQNKAKYPKWKKDKPLQDNLQSKGGWIGMTDKYWLAALVPQQSEMIKGRFQVKPVSGVDVYESAFTGAPKSLAAGATVTNTTRLFAGAKTVPLLTRYQYGGKPVVWWEFWNRPANVIPNFDKAVDWGMFEVITRPIFNVLEIFYKMVGNFGVAIMLLTVALKLILFPLADKSYESMAKMKKIAPEVEKLKVKNKDDPAKQQQEMMALYAKEKINPMMGCVPMLIQIPIFYSLYKVLTVTIEMRHAPFFGWITDLSARDPSTFMNLFGLIHWDPATAPLIGAFLSGPLHIGVWPLLYGFTMWLTTAMNPPAGDPIQQKIFQFFPIVFTFTLSQFAVGLVIYWCWSNVLTILQQYIIMHRYKVDNPIDQLVNRLRGKTVEAT
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_FRATM
Sequence: MKATQTLIATTKELPKEAVLISHQYMLKAGLIKKLASGIYTWMPLGLKVLQKIQNIVRDEMNKAGASELLLPSILPSELLQETHRWDKFGPELLKLHDRHNRDFCYGPTHEEPIVDMARDTIKSYKQLPLNLYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHENSQCLRNTYNTMYATYCNILDKIGLAYRPVKADTGAIGGDNSHEFQVLANAGEDIICYSNGSDYAANIELATYAKPDLSKRVNSQNTIEKIHTPNIKTIEKLYKEMSFDIKKTIKTMVIKDAGGNFFALVIRGDHELNETKINKLDQIIAPYTLATKEEIFSIFNANPGSLGIYNCPISIIADYSAIAITDLVCGANEDDYHFTNVNWDRDVTNYQIADIRNVVTGDISPDCKGTLELTNGIEVGHIFELEDVYSKPMNANIIGQDGKSKPMLMGCYGFGVSRVMAAAIEQSHDENGIIWPESIAPYQVAILPINYNKSDKVKEVADKLYQDLLGDGIDVLLDDRGARPGVMFADADLIGYSHHVVIGDKLLEQGLIEYKNRKTQEKQEITIAELIKILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS_BRSVR
Sequence: MATTAMRMIISIIFISTYVTHITLCQNITEEFYQSTCSAVSRGYLSALRTGWYTSVVTIELSKIQKNVCNSTDSNVKLIKQELERYNNAVVELQSLMQNEPASSSRAKRGIPELIHYKRNSTKKFYGLMGKKRKRRFLGFLLGIGSAIASGVAVSKVLHLEGEVNKIKNALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKELLPKVNNHDCKISNIATVIEFQQKNNRLLEIAREFSVNAGITTPLSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSVVKEEVMAYVVQLPIYGVIDTPCWKLHTSPLCTTDNKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPTDVNLCNTDIFNAKYDCKIMTSKTDISSSVITSIGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNRGVDTVSVGNTLYYVNKLEGKALYIKGEPIINYYDPLVFPSDEFDASIAQVNAKINQSLAFIRRSDELLHSVDVGKSTTNVVITTIIIVIVVVILMLIAVGLLFYSKTRSTPIMLGKDQLSGINNLSFSK
What is the function of this protein?
Major determinant of the species specificity of RSV infection.  The trimer of F1-F2 (F protein) also facilitates the attachment and entry into the host cell.  Later in infection, F protein expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis.
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
[Fusion glycoprotein F0]: Host Golgi apparatus membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Fusion glycoprotein F1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein. Note=Localized at the host apical membrane. SUBCELLULAR LOCATION: [Fusion glycoprotein F2]: Virion membrane. Host cell membrane. Note=Localized at the host apical membrane.
Protein: UREF_STAS1
Sequence: MIDHAHLRLFQFCDSQFPTGAFSHSFGLETYIQRDTVHDEESFQQWLVLFLNEQLTYADGLTMRLVYDALNENDTKAILKLDRILFVQNLPKETRQGSKQMGNRMVKLASELYDSDWINWYHAQMKDKKASLHPAICFTMLGHHLGVDIETIIDYYLYQNVSSLTQNAVRAIPLGQTAGQRIVHKMIPIMKETRDHIMTIPASQLGITAPGLEINQMEHENVNVRIFIS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CK2N2_HUMAN
Sequence: MSEILPYSEDKMGRFGADPEGSDLSFSCRLQDTNSFFAGNQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMGEKPPSGV
What is the function of this protein?
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2) (PubMed:11444830).  Traps Ca(2+)/calmodulin on CAMK2 (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase II inhibitor 2, CaM-KII inhibitory protein, CaM-KIIN.
What is the protein family that this protein belongs to?
Belongs to the CAMK2N family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Synapse. Note=Excluded from nucleus when coexpressed with activated CAMK2.
Protein: RL22_STRM5
Sequence: MEAKAILRTARISPQKARLVADQVRGLPAERAVNLLKFSDKKAAHLIKKVVESAIANAENNQGADVDELKVQTIMVDEGPTLKRFMARAKGRGTRILKRTSHITVVVGAAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RGDSR_HUMAN
Sequence: MRKLLTNLPAAAVLSAQVYSAVLQGLWEENVCGTPGRTRVCTALLYGQVCPFQDSTDGLRTITSILFNWPPENTSVYYQPPQRSSFRIKLAFRNLSWPGLGLEDHQEIVLGQLVLPEPNEAKPDDPAPRPGQHALTMPALEPAPPLLADLGPALEPESPAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCRGSVKNQPSEELPDMTTFPPRLLAEQLTLMDAELFKKVVLHECLGCIWGQGHLKGNEHMAPTVRATIAHFNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQLHKTWAGVSSKSMKELKELCKKDTAVKRDLLIKAGSFKVATQERNPQRVQMRLRRQKKGVVPFLGDFLTELQRLDSAIPDDLDGNTNKRSKEVRVLQEMQLLQVAAMNYRLRPLEKFVTYFTRMEQLSDKESYKLSCQLEPENP
What are the official names of this protein?
Ral-GDS-related protein, hRGR, Ral guanine nucleotide dissociation stimulator-like 4, RalGDS-like 4.
What are the subcellular locations of this protein?
Cytoplasmic vesicle.
Protein: CAP12_AGGAC
Sequence: MKKKIFIGSSSEELRIAEKVKKILEQDNEFEVTIWNDNSIWDNSVFKLNHNFLTDLLNSSLSSDFGILIGTCDDKVIVRGTERLQPRDNVLFELGFFIGKLGLDNCAFLIDKNIHILSDVQGITLARANMGDPDELKRAVNCIKEHFKHQPNSGINFFPSSTLASVYHENFIKPTCQTIIEDNGILDTAGKKHTNCLVKIIIPNKINIDVNSQFQILKNKISTNTLSFNYKGRPRNISIEIVESSEENTTIIDFPTIISGIYYAISNLLPQDSETDSITYRNILARELDRFVNTLYKFIKRDGYDEIVKIVYEDKLY
What is the function of this protein?
The effector protein for this CBASS system.  Binds c-di-GMP and 3'-3'-cGAMP, but not c-di-AMP, 2'-3'-cGAMP or cUMP-AMP (PubMed:32877915).  Upon activation by c-di-GMP forms filaments which hydrolyze NAD(+); filament formation is required for enzyme activation (By similarity).
What are the official names of this protein?
CD-NTase-associated protein 12, Cap12, NAD(+) hydrolase, TIR-STING, AaSTING.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the bacterial STING family.
Protein: MATK_WISFR
Sequence: MKEYQVYLERDRSRQQDFLYPLIFREYIYGLAYSHDFNRSIFVENVGYDNKSSLLIVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISDGFAVVVEIPFFLQLSSSLEEAEIVKSYHNLRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDASFFHLLRFFLYHFSNRNSLITPKKSISTFSKSNPRLFLFLYNFYVCEYESIFRFLRNQSSHLRLKSFSVFFERIFFYAKREHLVKVFPKDFSSTLTFFKDPFIHYVRYQGKSILASKNAPLLMNKWKHYFIHLWQCFFDVWSQPGTIHINQLSEHSFHFLGYFSNVRLNRSVVRSQMLQNTFLIEIVIKKLDIIVPIIPLIRSLAKAKFCNVLGHPLSKSVWADSSDFDIIDRFLRICRNLSHYYNGSSKKKNLYRIKYILRLSCIKTLACKHKSTVRAFLKKSGSEELLEEFFTEEEEILSLIFPRTSSTLQRLHRNRIWYLDILFSNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CABS1_MACFA
Sequence: MAEDGLPKIYSHPPTESSKTPTAATIFFGADNAIPKSETTITSEGDHVTSVNEYVLESDFSTTADNKLTPTKEKLRSEDDMGTDFIKSTTHLQKEITSLTGTANSITRDSITENFMTVKIGNISSPVTTVSLIDFSTDIAKEDILLDTIDTGDAEILITSEVSGTLKDSSAGVADTPAFPRIKDEADMNNYNSSIKSNVPADEAIQVTDSIIPEAEIPPAPEVNFTTIPDITALEEEKMTKIDLSVLEDDTSAVATLTDSDEEKFITVFELTTSAEKDKDNQEDTLLTDEESPEGANMWMERETATEAETHSVLLTAVESRYDFVVPASIATNLVEDSSTEEELSETDRTETVPKITEPFSGTSSVLDTPDYKEDTSTTETDIFELLKEEPDEFMI
What is the function of this protein?
Calcium-binding protein (By similarity).  Essential for maintaining the structural integrity of the sperm flagella (By similarity).
What are the official names of this protein?
Calcium-binding and spermatid-specific protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion inner membrane. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mostly cytoplasmic, but associated with the mitochondrial inner membrane during the last steps of spermatid differentiation. Localizes to the principal piece of the sperm flagellum (By similarity).
Protein: PGLR2_PECPM
Sequence: MEYQSGKRVLSLSLGLIGLFSASAWASDSRTVSEPKTPSSCTTLKADSSTATSTIQKALNNCDQGKAVRLSAGSTSVFLSGPLSLPSGVSLLIDKGVTLRAVNNAKSFENAPSSCGVVDKNGKGCDAFITAVSTTNSGIYGPGTIDGQGGVKLQDKKVSWWELAADAKVKKLKQNTPRLIQINKSKNFTLYNVSLINSPNFHVVFSDGDGFTAWKTTIKTPSTARNTDGIDPMSSKNITIAYSNIATGDDNVAIKAYKGRAETRNISILHNDFGTGHGMSIGSETMGVYNVTVDDLKMNGTTNGLRIKSDKSAAGVVNGVRYSNVVMKNVAKPIVIDTVYEKKEGSNVPDWSDITFKDVTSETKGVVVLNGENAKKPIEVTMKNVKLTSDSTWQIKNVNVKK
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Endo-polygalacturonase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RET4A_ONCMY
Sequence: SDCQVSNIQVMQNFDRSRYTGRWYAVAKKDPVGLFLLDNVVAQFSVDESGKVTATAHGRVIILNNWEMCANMFGTFEDTPDPAKFKMRYWGAASYLQTGNDDHWVIDTDYDNYAIHYSCREVDLDGTCLDGYSFIFSRHPTGLRPEDQKIVTDKKKEICFLGKYRRVGHTGFCESS
What is the function of this protein?
RBP delivers retinol from the liver stores to the peripheral tissues.  In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
What are the official names of this protein?
Retinol-binding protein 4-A, Plasma retinol-binding protein 1, PRBP-1, Plasma retinol-binding protein II, PRBP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YOG4_CAEEL
Sequence: MTADDFIETSERSATAEEGARARANFRLVSLAFQKETDSSLFLTLSQCHIELGGLEKHCRGRIERKRGREALRLGPGTKYNCPFPIVSRLDSVSLLFEED
What are the official names of this protein?
Uncharacterized protein ZK112.4.