PharMolix/UniProtQA huggingface dataset:
Protein: FIBB_CANLF
Sequence: HYYDDTDEEERIVSTVDARGHRPLDKKREEA
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: ULAD_SALHS
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: NSRR_ECOL5
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: PSTB_GEOSL
Sequence: MSASVQPVLKAESKNLNFYYGDFKALKGISLPVHDKRITALIGPSGCGKSTFLRCFNRMHDLYPGNRYDGEITLNPDGVNILSPKVDPIEVRMRISMVFQKPNPFPKSIFENVAYGLRVRGISKRSVLEEKVEEALTNAAIWNEVKDRLSDLAFNLSGGQQQRLCIARALAIDPEIMLFDEPTSALDPIATANIEELMAELKERFTILIVTHNMQQAARVSDFTAFLYLGEVVEFNDTKKIFTTPDNPRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TYB10_HORSE
Sequence: MADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
What are the official names of this protein?
Thymosin beta-10.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPE_PROM5
Sequence: MAISLKVLAPNQNVYEGDAEEVILPSTTGQIGVLPGHISLVTAIDIGVLRLRMNSKWTSIALMGGFAEIESDEVIVLVNSAEIGSEINTQNAEEALKKAKSAISKFPENEKSPEKIKALNEISKAEARFQASKN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: LUCI_AQULA
Sequence: MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLEKSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSLGISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKGSSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAILTVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRSELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDKPGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWLHTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAGELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREILKKPVAKM
What is the function of this protein?
Produces green light.
What are the official names of this protein?
Luciferin 4-monooxygenase, Luciferase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RDGC_XYLF2
Sequence: MFFRNLTLFRFPTSLDFSQIDSILPNARLRPVGPLEMTSRGFISPFGREEQEVLNQRQGDFLWLTVGSEDKILPASVVNDLLTRKCSEIEEKKGHPPGGRERKRIKDDLIHELLPRAFVKNSRIDAMLDLRYGYVAVDTASRKAAETVISEIRDLLGSFPALPLNAEISIRSMLTSWIAGEPLPEHLNLGDECEMKDATEGGAIIKCQHQALRCEEIDKHLEVGKQVSKLALILDDHVSFVLGDDLVIRKLKFLDGMLDQLEHSDTDGIRAELDARFALMSAEIRRLFLLLEVPLKLSKANN
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS3A_USTMA
Sequence: MAVGKNKKLSKGKGQKKRAVDPFTRKDWYDIKAPTFFENRNVGKTFVNRSQGLKNADDSLKGRIVEASLADLNKDDEQAYRKFKLKVDGIQGRTCLTNFYGMDFTSDKLRSLVRKWQSLIEAHQDVKTTDGYLLRVFVIAFTKKRANQVKKNTYAKSSHIRAIRQKMFEIVQREANSCDLREFVAKLIPEVIGREVEKATQGIFPLKDVYVRKVKVLKAPKDDLNKLLEVHGGAAIAGAEDAGVKARNTEFKEPAPLASV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSBA_CHRSD
Sequence: MRNATSWSLYRRLLSYVRPYWKAFLAAVVGYAIYAASSTALAEMMKRLIDGIQNPDAAFRLMLPLFVIGMFAARGVGTFLGTYYMSDVARNVVHALRCEVFNHMLRLPGRFFDMHSSGHLLSRVTYHVEQVTGAATNAITIILREGLFVIGLVSYLLWTNWMLTLIFMAVTPLIGLVVNYTSKRFRRLSRRIQNSMGDVTHVASEALSGYRVVRTHGAEAYEKARFAEASDYNREQSMKVALTKAVSTPVIQLLVALSLAGLVWLAMSPALMASMTPGEFVAFITAASLMAKPVRQLTEVNSTIQKGLSASQELFGLLEQPPEVDEGSYVPARIDGRVRFEGVRFRYGEDQAEVLKGIDLDVPQGEMIAIVGRSGSGKSTLVSLMPRFYRPTEGRVLLDDVDIQEYALSPLRQRIALVSQQVTLFNTTIAANIAYGHPDADREAVESAARSAYAHEFIERLPNGYDTVVGDNGVMLSGGQRQRLAIARAIFKDAPLLVLDEATSALDTESERYIQQALERVCRGRTTFVIAHRLSTIERADRILVMEQGEIIESGTHGELLAQDGAYAALHQLQFQEAE
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MVP_PPVD
Sequence: MSTIVFGSFTCHLDAAIHQDNADRLAKAWTRPENRQVSNVHLLCRRAAKSLINTYESATASAWKGLEEKLQPMFAKREFSKTVTKRKGLRCFKESSEKFIEKKLRKQYQEERERFQFVNGPDAIVNQISVDKCEASVWVPFPHIIEKPSFATPSMKKKVVFTKVRMSEASLQLFMRRVAANAKANGQKVEIIGRKRVVGNYTTKSRLTYFRTHVRHLDGSKPRYDLVLDEATKKILQLFANTSRFHHVHKKGEVTPGMSGFVVNPINLSDPMQVYDTDLFIVRGKHNSILVDSRCKVSKKQSNEIIHYSDPGKQFSDGFTNSFMQCKLRETDHQSTSDLDVKECGDVAALVCQAIIPCGKITCLQCAQKYSYMSQQEIRDRFSTVIEQHEKTAMDNYPQFSHVLAFLKRYRELMRVENQNYEAFKDITHMIGEDRKEAPFSHLQQINELIIKGGMMSAQDYIEASDHLRELARYQKNRTENIRSGSIKAFRNKISSKAHVNMQLMCDNQLDTNGNFVWGQREYHAKRFFRNYFDVIDVSEGYRRHIVRENPRGIRKLAIGNLVISTNLAALRKQLLGEECIHFEVSKECTSRRGENFVYQCCCVTHEDGTPLESEIISPTKNHLVVGNTGDSKYVDLPTAKGGAMFIAKAGYCYINIFLAMLININEDEAKSFTKTVRDTLVPKLGTWPSMMDLATACHFLAVLYPETRNAELPRILVDHEAKIFHVVDSFGSLSTGMHVLKANTINQLISFASDTLDSNMKTYLVGGSEVDKCDEFKNVKLLIRSIYKPQIMEQVLKEEPYLLLMSVLSPGVLMALFNSGSLEKATQYWITRSHTLAAITSMLSALAAKVSLASTLNAQMSVIDEHAAVLCDSVFDGTKPYASYMMAVKTLERMKARTESDHTLNDLGFSVLRQATPHLVEKKLSPGIGASLERVKLVGKILCNLGIAAVAKTYTKTFHPKRRRRFRRQVRHLRSVITWQPVQTPERRSPTEKRRCGLLYTPVDGEAILQSHRNFHKFSSKHS
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: NADK_SULIM
Sequence: MRVKIVSKPTSQLNNIIEKIKNISTKLGFEVVDKDFDYVIAVGGDGTLLRAVKQNKPVIAVKAGRRGLLMDVPVDKFEEALLRLKKGDYEEEEYMLLEMIYNDKVELGFNEVGILYDRPEAIKVGISFDTERVSVEGDGVLVSTPQGSSGWGMSATNSLLYKDLSAIEIIFVNPIFYYLRSVVIPPKPLTLRLEDKGYPQTARAVVDGEVVTLIKTNQEITVRVSQRKAKILRFFKLDLIGEVLHAYHI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RU1C_DROME
Sequence: MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHRDNVKFYYQKWMEEQAQHLIDATTAAFKAGKITNNPFAGGPGGAPPKPAGVSIPPPNMGAPPRPGMPGMPYMPPLMNPMMGMRPPPIMNPMAMMGPPPPLGTIPGVRPGIMNGPK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region (By similarity).  Regulates alternative splicing of a distinct group of target genes.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CJTL7_EPIJA
Sequence: MMIKVLLLLSSALVLFTPEAEGGCGCHTECSLQCSFSGCGYVCGLRCRCSWGK
What is the function of this protein?
In vivo, only causes a weak change in behavior in shrimps (C. multidentata) (slight twitching of the walking legs), but no lethal effect is observed.  No activity is observed when injected into fly larvae (M. domestica).
What are the official names of this protein?
Toxin CjTL7.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: NRX3B_CHICK
Sequence: MHLRTNPSICPGRRPAWTLWMCSLFWGCIVSSVWSSSNVASSASSSSSVSQAQYEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRTDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEESTPVNDGKYHVVRFTRNGGNATLQVDSWPVNEHYPTGNTDSERFQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDRGRLFQGQLSGLYYNGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTPTTSVPPEMSTTVMETTTTMATTTTRKNRSPPSIQTTDDIVSSAECSSDDEDFIDCEPSTGKSGGELVIPLLVEDPLDIPPIATRAPFITLPPTFRPLLTIIETTKDSLSMTSEAGLPCLSDQGSDGCDDDGLVISGYGSGETFDSNLPPTDDEDFYTTFSLVTDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETGRTTTTSLSPELIRSTASSSTGMVPKLPAGKMNNRELKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVVRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSSKSGHKKQKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion (By similarity).  Plays a role in angiogenesis.
What are the official names of this protein?
Neurexin-3-beta, Neurexin III-beta.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL13_METNO
Sequence: MKTFSLKPADVEKKWVIIDAEGLVVGRLASIVAMRLRGKHKPQYTPHVDCGDNVIVINADKVKFTGRKYDQKVYYHHTGYPGGIKERSAKFILEGRFPERVVEKAVERMLPRGPLFRKILGNLRVYKGSEHPHAAQQPETLDVAALNRKNVSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: UXUA_BURCJ
Sequence: MKMSFRWYGESDPVSLQYIRQIPGVTHIVSAIYDEPVGEVWPAHKIEALKATIERAGLQFDVVESVPVHEDIKLGKPGRDRLIDHYRQTIRHLGAAGIRVVCYNFMPVFDWTRTELSKTLDDGSTCLAFSTDAVDRIDPNDGIALPGWDSSYRPEQLQALLADYRDVDENALWANLEYFLKAIIPVAEEAGVKMAIHPDDPPRPIFGLPRIVKNRDDLARIVRLVDSPANGLTLCSGSLGAGPENDVEALVREFGAMGRIHFAHIRNVKVDANGDFEETAHLSSCGSLDIAAIVKAYHDTGFTGYVRPDHGRMIWGETGKPGYGLYDRALGAVYLNGLWEALAKFDRAPQASQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: ARC_COREF
Sequence: MGDMASSTDPAAHNSFSDFNREEMTRLADNVRSLQRTNQDLSARNTKLAEMLKSSRDKLSMMYQQLEDMAQPPSLYGTFLEMSKDGTNAEIFAGGRRMRVAMSPMLCAGDLMPGVQVRLGEGNQILEACDFEQTGDLATLMEMIGRDRALISDRSGEERVVKLAGPLMDRTRKLPRPGDTLLVDRRAGYAFENIPKTEISKLALEEAPDVSYVDIGGLDDQIELIQDAVELPFLHPEMYRSYKLHPPKGVLLYGPPGCGKTLIAKAVANSLSQRIGDAGTSYFINVKGPELLNKYVGETERQIRVIFERARELAGDGRPVIIFFDEMESIFRTRGSGISSDMETTVVPQLLAELDGVEDLSNVIVIGATNREELIDPAILRPGRLDIKIRVQRPNRSGARDIFARYITDAIPLAAPVDELIDTAVDHLFTPRPYVRLTLIDGTVETLNYHDFVSGAMIANIVDRAKKSAIKDHIDGRTTGLSAEHLIHAIDQENQQSEDLPNTSNPDEWTRIIGRQGKRVAEVEVV
What are the official names of this protein?
AAA ATPase forming ring-shaped complexes, ARC.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: TRUB_OENOB
Sequence: MYNGIVLVDKPAGLTSFDVVAKLRKIFQQKQVGHTGTLDPSVTGLLVIVLGKATKLIDYLQENQKQYRGTLILGLKTDTQDMDGQVTEMQFLKEAIADFKKKAAFDSFLGSSDQLPPMYSAVKVGGKHLYELARKGETIERKSRKIKVMEFQQVGGSKFDASKGQEYINFVATVSKGTYIRTLIEDFGAKLGLPATMMRLRRIEADGYDVKNSINLEEILASKTPRKFIIPMEKLLPTLPKYSVGSDDWQLIKNGGWLKELPISVSPVKIFYNNSFQAIYEKQDGFYKPKKMLIHEDH
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ATP6_ASCSU
Sequence: MTNVYFLDIFMFVYVLQFLFYFKESMLGVLVNKFLGLLVVVFSYTDSLPLSSVISVFTFLVLLTCCFGGYFMYSFCPCGMIEFTFVYAMVAWLSTLLTFITSEKFSIYISKAGDSFLKTFSMLLVELVSEVSRPLALTVRLTVNVLVGHVISMMLYQLLELYLGIFYVWIVVLAIVMECFVFFIQSYIFSRLIYLYLNE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y633_STAES
Sequence: MFPLVEFCISNMAKGSDVVFEKLENDPNIDVLEYGCLQNCGLCASSLYALVDGDIVEGNTPDDLLKNIYQHIEDNDITNLL
What are the official names of this protein?
UPF0349 protein SE_0633.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: PETD_OENEH
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAILEPSMLGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPSGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IF1_ERYLH
Sequence: MAKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPYDLTKARITYRFMPGRGGPGQGPGPQ
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTAS_STAES
Sequence: MSLPKKKIGIFAFFLLTVFTITLKTYFSYYVDFSLGVKGLVQNLILIMNPYSLIALVLSVFLFFKGKKAFWFIFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQAGNVESMGGAVSASFKWYDFVYFIDTIIYLAILIFKRKWLDNRAFSKKFVPVVMATSVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQKRTEPNPEYYGAAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGNQDFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAYSLKGDNTYQSLPAILDQKQGYTSNVMHGDYKTFWNRDQVYKHFGIDNFYDATYYDMSDDNIVNLGLKDKPFFKASADYQSKMKKPFYSHLITLTNHYPFTLDEEDASIDKPNTGDSTVDGYIQTAHYLDQALEEYITDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWLKVPGKSGGVNKEYAGQMDVMPTLLHLVGIDSKNYLMFGSDMFSKQHNNVVPFRNGDFITEDYKYVNGKIYSNKDNELLTEKPKDFDKNKKQVEKDLEMSDSVLNGDLFRFYKNPDFKKVNPGKYEYKSGPKGNEKK
What is the function of this protein?
Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.  Is required for staphylococcal growth and cell division process (By similarity).
What are the official names of this protein?
Lipoteichoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the LTA synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Processed glycerol phosphate lipoteichoic acid synthase]: Secreted.
Protein: C11B1_PAPHU
Sequence: MALRAKAEVCMAAPWLSLQRARALGTRATRVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEHLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLNPRRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALRKKVVQNARESVTLDIQPSIFHYTIEASNLALFGERLGLVGHSPSSASLSFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELALSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSTFPLLTFRAIN
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids.  Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11-deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cytochrome P450 11B1, mitochondrial, CYPXIB1, Cytochrome P450C11, Steroid 11-beta-hydroxylase, CYP11B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: OMPEA_ERWAM
Sequence: MKRNILAVLIPALLAAGAANAAEIYNKDGNKLDLYGKVKAMRYLSDADSNASNNADKSYTRIGFKGQTLINDQLTGYGQWEYNFSLSNSESSSDAQSGNKTRLGFAGLKLKDYGSVDYGRNYGVIYDVEAFTDMMPEFGATGYTRTDTYMLTRGNSMLTWRNSDFFGLVDGLKIALQYQGKNEGSGTRATNVSNGDGYGASLSYKIVEGLTINGAMSSSNRLNANSASSTTSQKMAAYGSGGRAEAWATGLKYDANGVYLAGTYAETRNTNPFSGASYTFAGNSTATAVSGYANKVQNTELVAQYQFDSGLRPSLAYVQTKAKDIENGIGDADLSKFVDVAATYYFNKNMSAFVDYKVNLLSDSNKLHLNTDDIVAVGLVYQF
What is the function of this protein?
May play an important role in maintaining pathogenicity in plants.
What are the official names of this protein?
Outer membrane protein Omp-EA.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: UBP53_MOUSE
Sequence: MAWVKFLRKPSGNLGKAYQAGSLLSLAPTVGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRALTGHICQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDAAECFENILARIHFHLVPNRDADMCTSKSCVTHQKFAMTLYEQCVCRSCGASSDPLPFTELVRYISTTALCNEVERMMERHERVKPEMFAELLQAANTADDYRKCPSNCGQKIKIRRVLMNCPEIVTIGLVWDSEHSDLTEDVVRSLATHLYLPGLFYRVTDENATDSELHLVGMICYTSRHYCAFAFHTKSSKWVFFDDAHVKEMGTRWKDVVSKCIRCHLQPLLLFYANPDGTAVSTEDALRQVVHWSHYRSGEENMGCGKPIIYKPDNSKENGFGGQTKQKENHKFQTDISSLNRSQMQTSGRRAPVKLSHDQREKIKDISRECALKAIEQKNALSSQRKDLEKGQRKDTGRHRDLVDEVLASFKSGSPPASDGFRQQGNPHLYHSQGKGPCKHDRATHESYTSGKVISSSKSQNLLVPGEKTTGKAKSDSGTGYETDSSQDSRDKGGSYSSKTKSRHRGWKPMRETLNVDSVFSESEKRQHSPRRKSDIGSRPRCSKDQSFNNWPKANPKQKGLMTIYEDEMKQEAGSRSSLETNGKGAEKNLSAAESRGPGTSWQMQRTESGYESSDHVSNGSASLDSPGVEGSGAVMDVGGGKAFSEHIKMNSHNMDSMEYISHHCKDHPEGFRKELQDLEADDKIHELHPESHVQIKSHLIKRSQIGETNDKLFPSASPQTLAREHVYQTNEHKVERPDRSKCSERHNTENSEGTGLPFHVDESSVAGKRVDSNETVSPSSLPSSVRTAGLKPETGPLMFWSQQNITEQGYSDNSLSRELTLLSACNADSCQMPKLHCHRSPPPLPPKKYSTASAPRLERVGLSPDVGVTEAFNTNPSSLPKHSLSPASGPSLEGSPCMTQERDKETIQVKQLAANSYPSSCSTNSFQPDQDSTSVCPNETISLTTYFSVDSCMTDTYRLKYHQRPKLYFPESSGHHSNNSLSQTEQVEGSIT
What is the function of this protein?
Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing.  Maybe by modulating the barrier properties and mechanical stability of tight junctions (PubMed:26609154).  Has no peptidase activity (PubMed:26609154).
What are the official names of this protein?
Inactive ubiquitin carboxyl-terminal hydrolase 53, Inactive ubiquitin-specific peptidase 53, Per-hexamer repeat protein 3, Protein mambo.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cell junction, tight junction.