PharMolix/UniProtQA huggingface dataset:
Protein: ADT3_YEAST
Sequence: MSSDAKQQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:2165073).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 3, ADP/ATP translocase 3, Adenine nucleotide translocator 3, ANT 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: INSJ_ECOLI
Sequence: MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVALYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLKVYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMYLKKLKALAHPTKK
What are the official names of this protein?
Insertion element IS150 protein InsJ, ORFA.
What is the protein family that this protein belongs to?
Belongs to the IS150/IS1296 orfA family.
Protein: LIPB_FRATO
Sequence: MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y13D_BPT4
Sequence: MMNLTDIIDNCLENDTGDHRALDSETAQFIRITLMNDTLVNSIHPSVYDAIIVTKYPVELHKKMTGAVFIDKKNRFKDGQNIISSVIKSITKLRHEIYRVETAKSAYLVIMK
What are the official names of this protein?
Uncharacterized 12.8 kDa protein in cd-pseT intergenic region.
Protein: PURT_SHESM
Sequence: MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYPNAPAMQIAHRSHVINMLDAKALRAIIELEKPHLVIPEIEAIATQTLVEMEAEGLNVVPTARATQLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAIGKIGVPCVVKPVMSSSGKGQSVIRDVSQSAKAWQYAQEGGRAGGGRVIVEGFIPFDYEITLLTISAVNGIHFCAPIGHRQEDGDYRESWQPQAMSADVLAKSQAIASKVVEALGGYGLFGVELFVKGSDVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVVLVEGKSKNIRYQGLADALAAENTQLRLFAKPEIDGRRRLGVALARDKDIESAVNKALDSASKVKVIF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: PYRB_MYCLE
Sequence: MMRRHLLNAGDLSRDDAIAIFDDADRFAHALVGREIKKLPTLRGRTVITMFYENSTRTRVSFEVAGKWMSANVINVSPAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLADWTAAETGEDGPAVINAGDGTHEHPTQALLDALTIRQRLGSIEGRRILIVGDILHSRVARSNVVLLDTLGAEVVLVAPRTLLPIGVDGWPATVSCDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSCLYGLTERRQALLPGHAVVLHPGPMLRGMEIASSVADSSQSAVLQQVSNGVHVRMAVLFHVLVGTQSAEEEGAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ISPE_STRA1
Sequence: MKIFEKAPAKLNLGLDIKGRCDDGYHELAMIMVSIDLNDYVTISELKEDCIVIDSDSSKMPLNNDNDVFKAADIIKNQYGINKGVHIRLEKSIPVCAGLGGGSTDAAATIRALNRLWNLQMDYDEMVAIGFKIGSDVPYCLGGGCSLVLGKGEIVKPLPTLRPCWIVLVKPDFGISTKSIFRDIDCKSISRVDIDLLKSAILSSDYQLMVKSMGNSLEDITITKNPVISTIKERMLNSGADVALMTGSGPTVFSMCSTEKKADRVFNSMKGFCKEVYKVRLLR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: BR2_PELRI
Sequence: KLKNFAKGVAQSLLNKASCKLSGQC
What is the function of this protein?
Cytotoxic to cancer cells, acts via the activation of the lysosomal-mitochondrial death pathway and autophagy-like cell death.  Does not show significant hemolytic activity.
What are the official names of this protein?
Brevinin-2R.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RS17_CROS8
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ADH2_CANAL
Sequence: MSVPTTQKAVIFETNGGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWKGDWPLATKLPLVGGHEGAGVVVALGENVKGWKVGDYAGVKWLNGSCLNCEYCQSGAEPNCAEADLSGYTHDGSFQQYATADAVQAARIPAGTDLANVAPILCAGVTVYKALKTAELEAGQWVAISGAAGGLGSLAVQYAKAMGYRVLAIDGGEDKGEFVKSLGAETFIDFTKEKDVVEAVKKATNGGPHGVINVSVSERAIGQSTEYVRTLGKVVLVGLPAGAKISTPVFDAVIKTIQIKGSYVGNRKDTAEAVDFFTRGLIKCPIKIVGLSELPEVYKLMEEGKILGRYVLDNDK
What are the official names of this protein?
Alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_NASOF
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KS6R_MOUSE
Sequence: MGAVSCRQGQHTRVSAPQKGDNIQGHWVQGWKSLWCGMGTIRSGLEELWGLQRHQCLHQELLQPAPLLLEKPQSEWPVPQFISLFLPEFPVRPVREQQELKILGLVAKGSFGTVLKVLDCAQKAVFAVKVVPKVKVLQRDTLRQCKEEVSIQRQINHPFVHSLGDSWQGKQHLFIMCSYCSMDLYSLWSTVGWFPEDSIRLFAAELVLVLCYLHDLGIIHRDVKMENILLDERGHLKVTDFGLSRHLSQGARAYTICGTLQYMGEREAKVGREGDLRM
What are the official names of this protein?
Ribosomal protein S6 kinase-related protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL2_SHEB9
Sequence: MAVIKCKPTSPGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRLIDFKRDKDGIPAKIERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKIQSGVAAEIKTGNAMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVARDGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GCSH_BACTN
Sequence: MNFPQNLKYTNEHEWIRVEGDIAYVGITDYAQEQLGDIVFVDIPTVGETLEAGETFGTIEVVKTISDLFLPLAGEILEQNEALEENPELVNKDPYGEGWLIKMKPADASAAEDLLDAEAYKAVVNG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: FLGI_ECO45
Sequence: MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CCA_METBF
Sequence: METYTGIPEELKFAVLERIQPTEPEREKLFAIQEELASQVKIAAEKLGIPGVLVKMVGSAARGTWLSGTHDIDVFISFPEETSRKDLETLGMAIAREVARYAEHAEDRHAEHPYLNITYKGFDVDLVPCFRVASASQIKSAVDRTPFHNDFVKPRIKGHEDEVLLLKQFMRGGGVYGSELKTQGFSGYLTELLVIRYGSFKNTIYAACSWKPGEKIDIMQHGEIEHEEPLVVIDPTDPRRNVAAALSLDKFCTFIDHCREFLKNPELSFFFPAPILPLEDSEILEKLESRKSTQLAVVFKTPDVVEDVLFPQLYKMEQAVAALLKEYDFTVIKTGVWSGNTETAVMMELISGTLPNVKKHIGPPVWVKVHAEKFKEKYQAADGVFGGYIENGKYIFEILRKYPTARGLLEDRLMSCSLGKQVHQSVNEGFEIIENAGICRLKEYDFRIYLRKWI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: AADK_BACSU
Sequence: MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGLVKVLLDKDSFINYKVTPNDRQYWIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEMWKSLFTCYALFRKYSKAVSEGLAYKYPDYDEGITKYTEGIYCSVK
What is the function of this protein?
Mediates bacterial resistance to streptomycin (PubMed:3137862, PubMed:17609790).  Adenylates streptomycin on the O-6 residue (PubMed:3137862, PubMed:15984036, PubMed:17609790).  Adenylates streptidine on the O-6 residue (PubMed:17609790).  Does not act on spectinomycin, neomycin-B or kanamycin (Ref. 5, PubMed:15984036).  Specific for ATP and GTP nucleotides incorporating a purine ring.  No reaction with CTP or UTP (PubMed:15984036).
What are the official names of this protein?
Aminoglycoside 6-adenylyltransferase, 6-O-adenyl-transferase, AAD(6), ANT(6), Aminoglycoside inactivating enzyme, Sm inactivating enzyme, Streptomycin 6-adenylyltransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF7_BPCHP
Sequence: MCLLVIKSVMLSIVISLRRLLDYLDLTLQVL
What are the official names of this protein?
Uncharacterized protein ORF7.
Protein: DOG1_ARATH
Sequence: MGSSSKNIEQAQDSYLEWMSLQSQRIPELKQLLAQRRSHGDEDNDNKLRKLTGKIIGDFKNYAAKRADLAHRCSSNYYAPTWNSPLENALIWMGGCRPSSFFRLVYALCGSQTEIRVTQFLRNIDGYESSGGGGGASLSDLSAEQLAKINVLHVKIIDEEEKMTKKVSSLQEDAADIPIATVAYEMENVGEPNVVVDQALDKQEEAMARLLVEADNLRVDTLAKILGILSPVQGADFLLAGKKLHLSMHEWGTMRDRRRRDCMVDTEVIFDACTTVNSGPRPTETTNNERN
What is the function of this protein?
Required for the induction of seed dormancy (PubMed:17065317, PubMed:26620523, PubMed:22829147).  The level of DOG1 protein in freshly harvested seeds determines the level of seed dormancy (PubMed:22829147).  Determines the temperature window for germination by regulating the expression of micropylar endosperm-weakening genes through temperature control of the gibberellins metabolism (PubMed:25114251).  Regulates seed dormancy and flowering time through an influence on levels of microRNAs miR156 and miR172 (PubMed:27035986).  Regulator of seed maturation interfering with abscisic acid signaling components and activating ABI5 (PubMed:26729600).  In cv.  Cvi-1, enhances glucose induction of ABI4 (PubMed:18410483).
What are the official names of this protein?
Protein DELAY OF GERMINATION 1, GLUCOSE SENSING QTL 5.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: UVRA_SALTY
Sequence: MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVIDRFKVRNDLSQRLAESFETALELSGGTAVVADMDDEKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPDLSLAGGAIRGWDRRNFYYFQMLKSLAEHYKFDVDAPWASLSANVHKVVLYGSGKENIEFKYMNDRGDTSVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCEGTRLNREARHVFVENTPLPAISDMSIGHAMDFFTNLKLSGQRAKIAEKVLKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRNLGNTVIVVEHDEDAIRAADHVIDIGPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKQRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRSRGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHQLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVAGTPETVAECEASHTARFLKPMLK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_PECAS
Sequence: MSETIVSEQTVSEFSPASADASQSVKASVGKINLLDLNRQQMRDLFMSMGEKPFRADQVMKWMYHYCCDDFNQMTDINKVFRTKLQEIAEIRAPEVVDEQRSSDGTIKWAILVGGQRVETVYIPEEERATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGAFKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRNEIMPINKKYNIEMFLSAVRRYLEKSNANQGRVTVEYVMLDHINDGTEHAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVVDRTKRTLKKKMAGEPIAVKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_RHOE4
Sequence: MAVKIKLTRLGKIRNAQYRVVIADSRTRRDGRAIETIGKYHPKEEPSLIDIDSERAQYWLSVGAQPTEPVEALLKITGDWQKFKGLPGTEGTLRVKEAKPTKLELFQAALAQAENEPVAEAITPKKKKAAKADEAKAEDTAADAEAPAADAEAADK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: H2AY_CAPO3
Sequence: MAKSKKIVAATSGSRSRSSRAGLAFPVGRVHRLLRKGHFADRIGSGSAVYLAAVLEYLTAEILELAGNAARDNRKTRINPRHIQLAVRNDEELSKLFTGVVIPSGGTLPHIWPALIPNEAKDSSTASASFNAPAKSATVKALAAAKSAGKKPAAVSSSSAAASSSSSASSSSSVAPKKPVRGFTILSKKTLHLGQTLYVVNGDLTEVRCDAVVHPTNGTMSFAGQVGGAIRAAAGAGVDAEVNSYMSEHSQLQVTKAAITSGHNLPSKWIVHVHSPNYSNAATATDALTQTIRNALTLADTKSIKTIAFPSIGSGNNHFPKHIAAQTILQAISAYFMSIMSSSIKEVYFVLFDQESINVYNAELINTN
What is the function of this protein?
Specifically binds poly-ADP-ribose and plays a key role in NAD(+) metabolism (PubMed:34887560).  Able to bind to the ends of poly-ADP-ribose chains created by PARP1 and cap them (PubMed:34887560).  This prevents PARP1 from further addition of ADP-ribose and thus limits the consumption of nuclear NAD(+), allowing the cell to maintain proper NAD(+) levels in both the nucleus and the mitochondria to promote proper mitochondrial respiration (PubMed:34887560).
What are the official names of this protein?
Histone macroH2A1.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
Protein: PP135_ARATH
Sequence: MFALSKVLRRTQRLRLGACSAVFSKDIQLGGERSFDSNSIASTKREAVPRFYEISSLSNRALSSSAGTKSDQEEDDLEDGFSELEGSKSGQGSTSSDEDEGKLSADEEEEEELDLIETDVSRKTVEKKQSELFKTIVSAPGLSIGSALDKWVEEGNEITRVEIAKAMLQLRRRRMYGRALQMSEWLEANKKIEMTERDYASRLDLTVKIRGLEKGEACMQKIPKSFKGEVLYRTLLANCVAAGNVKKSELVFNKMKDLGFPLSGFTCDQMLLLHKRIDRKKIADVLLLMEKENIKPSLLTYKILIDVKGATNDISGMEQILETMKDEGVELDFQTQALTARHYSGAGLKDKAEKVLKEMEGESLEANRRAFKDLLSIYASLGREDEVKRIWKICESKPYFEESLAAIQAFGKLNKVQEAEAIFEKIVKMDRRASSSTYSVLLRVYVDHKMLSKGKDLVKRMAESGCRIEATTWDALIKLYVEAGEVEKADSLLDKASKQSHTKLMMNSFMYIMDEYSKRGDVHNTEKIFLKMREAGYTSRLRQFQALMQAYINAKSPAYGMRDRLKADNIFPNKSMAAQLAQGDPFKKTAISDILD
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g80270, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TIG_THEVB
Sequence: MTTEPRSNSQLLATIEVSGTHSQQVYNQVVNDLLRHTQVPGFRKGKAPRQLVLQQLGRERLRYLAMEKLIEDAVKTAVEKNNIPYLGNLELAGGITELLDQFHPGENFSFSVTFDVEPEVTVTAYKGLTIEYNPVTYNPATVEKLLQQHQRQHATLIPVEDRPAQWGDDVTLKLLTKDENGEVVKELSADELPLSLDEDQPFLLQEIPAAVVGMAIGEAKTVTVSVAEEAEAPRQLTAEIELLGIKVPELPPLDDAFAAEHSEFSTMAELRAYLEQNHQERAKHQDKQAKEAALIDTLIAQNPVELPKTLIRKEADVKVRTTLMQIQSQGVDLHKIMTEELYERMRQEAEPAATKEVHSRLLLKAIARQEGIEPTPEAVEERLNRYKEMLGNKTAKNLEQLRKLAHDEVQQEQTLSWLLEQNTFQPVQSDVATAEPTATAEAPTEIQTEAVAQTPSQPQKRSGKKASSAPSQE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EID1_HUMAN
Sequence: MSEMAELSELYEESSDLQMDVMPGEGDLPQMEVGSGSRELSLRPSRSGAQQLEEEGPMEEEEAQPMAAPEGKRSLANGPNAGEQPGQVAGADFESEDEGEEFDDWEDDYDYPEEEQLSGAGYRVSAALEEADKMFLRTREPALDGGFQMHYEKTPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE
What is the function of this protein?
Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation.  Inhibits EP300 and CBP histone acetyltransferase activity.  May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation.  May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
What are the official names of this protein?
EP300-interacting inhibitor of differentiation 1, 21 kDa pRb-associated protein, CREBBP/EP300 inhibitory protein 1, E1A-like inhibitor of differentiation 1, EID-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May shuttle between nucleus and cytoplasm.
Protein: FLGR_HELPY
Sequence: MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGLEFLRLLEGKYESIVITGNATLNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQKKHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANVMLLGESGVGKEVFAHFIHQHSQRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEMPLQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIVPITIAPLRERVEEILPIAEIKLKEVCDAYHLGPKSFSKNAAKCLLEYSWHGNVRELLGVVERAAILSEETEIQEKDLFLER
What is the function of this protein?
Member of the two-component regulatory system FlgR/FlgS that induces the transcriptional induction of the genes needed in motility and flagellar biogenesis (PubMed:15231786, PubMed:9882675).  Upon phosphorylation by FlgS, functions as a transcriptional regulator and activates transcription of RpoN-dependent flagellar genes (PubMed:10735847, PubMed:15231786).
What are the official names of this protein?
Transcriptional regulatory protein FlgR.
Protein: Y273_META3
Sequence: MTNYHVTLQAPYIVKNIEDVEDALGVAISHIGKILNKKGMEYVDIDVGLTICPKCGEPIDCVLVVARTAIVGILLSMKIFNAESSEHAVRIAKSSLGRTLKDIPLEIVDVVEI
What are the official names of this protein?
UPF0212 protein Maeo_0273.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: SDC1_CRIGR
Sequence: MRRAALWLWLCALALRLQPVLPQIMAVNVPPEDQDGSGDDSDNFSGSGTGALPDITLSRQTSSTLKDVWLLTATPTAPEPTSRDTEATFTSILPAGEKPGEGEPVLIAEVDTSSTTWDKELEVTTRPRETTQLLVTHRVSTARATTAQAPVTSHPHRDVQPGLHETLAPTAPGQPDHQPPSGGTSVIKEVAEDGATNQLPTGEGSGEQDFTFETSGENTAVAAIEPDQRNQPPVDEGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
What is the function of this protein?
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.  Regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
What are the official names of this protein?
Syndecan-1, SYND1.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted. Secreted, extracellular exosome. Note=Shedding of the ectodomain produces a soluble form.
Protein: RL22_MYCUA
Sequence: MTTTTEFPSATAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASEPVAKVIASAAANAQNNNGLDPATLIVATVYADEGPTAKRIRPRAQGRAFRIRKRTSHITVVVESRPSKDQRSSKSSRARRAEGSKAAATAPAKKSSASKAPAKKAATKAESKTSEISEAKGGSD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.