PharMolix/UniProtQA huggingface dataset:
Protein: RS18_CLOB8
Sequence: MSREEGNNGRRPGGKMRRSRKKVCAFCVDKAEFIDYKDINKLRKYVTERGKILPRRISGTCAKHQRELTSSIKRARNIALLPFTTE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NDUV2_ARATH
Sequence: MLARLAAKRLLEIRQVFRQPTSQVTRSLSTALNYHLDSPDNKPDLPWEFSEANQSKVKEILSYYPSNYKQSAVIPLLDLAQQQNGGWLPVSAMNAVAKVIEVAPIRVYEVATFYSMFNRAKVGKYHLLVCGTTPCMIRGSRDIESALLDHLGVKRGEVTKDGLFSVGEMECMGCCVNAPMITVADYSNGSEGYTYNYFEDVTPEKVVEIVEKLRKGEKPPHGTQNPKRIKCGPEGGNKTLLGEPKPPQFRDLDAC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Matrix and cytoplasmic side of the mitochondrial inner membrane.
Protein: P2C50_ARATH
Sequence: MVELRQFSDLPIALSGISRIADPSPPPPVVAIRRRFKGGGNTRRIVFSVPLIFAFPFPTGTPKDVLVGIAAVFDGHSGSEASEMASQLLLDYFALHIYFLLDATFSKELTGKLPNSLMHLYDLDSQRFQDSLPLNFHLDILKEALLRAIYDIDATFTKEASTRKLDSGSTATIALIADGQLLVASIGDSKALLCSERYETPEEAKATLIKLYRERKRNQDSSPSRFSDLKLEHRTGLMRFIAKELTKDHHPDREDEMLRVKAAGGYVTKWAGVPRVNGQLAVSRSIGDLTYRSYGVISAPEVMDWQPLVANDSYLVVSSDGIFEKLEVQDACDRLWEVKNQTSFGAGVPSYCSISLADCLVNTAFEKGSMDNMAAVVVPLKSNLDWESQPKEQSVGPSGFKMKNTYALPCEFLSSQPNLFRMG
What are the official names of this protein?
Putative protein phosphatase 2C 50, AtPP2C50.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: FABH_NEOYE
Sequence: MGVHILSTGSSVPNFSVENQQFEDMIETSDHWISTRTGIKKRHLAPSSTSLTKLAAEAANKALYAANLKPTEISLIILATSTPDDLFGSASQLQAEIGATTPVAFDITAACSGFIVALVTAAQFIQLVYDNILVVGADTCLDGLIGQIELPVFYLVMVLEQLVLGQSLKNSILGFKLCTDGQLNSHLQLMNKPVNNQKFGGTEIPHGNYNSITMNGKEVYKFAVFQVPTVIRQCLNNLNISIDEVDWFILHQANTRIIEAIASRLSVPFSKMITNLEHYGNTSAASIPLALDEAIQSNKIQPGQIIVLSGFGAGLTWGAIVLKW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNAG_LISMO
Sequence: MARIPEEVIDQVRNQADIVDIIGNYVQLKKQGRNYSGLCPFHGEKTPSFSVSPEKQIFHCFGCGKGGNVFSFLMEHDGLTFVESVKKVADMSHLDVAIELPEERDTSNLPKETSETAKMVEMHQLTAKLYHYILMETEEGTAALTYLKERGMSEQMMTTFQIGFAPNHHATITSFLEKRGMDLQLAGAAGLLSERDDGQMVDRFRNRIMFPITNDRGQIIAFSGRLFDRDDGPKYLNSPETPVFNKRRILFHFSEARQAIRKQEEITLMEGFMDVISAEEAGVQNAVASMGTSLTEEHADLIKRLTNRAIICYDGDRAGIEAAYKAGTLLVERNRLDVFVLQLPAGKDPDDFIRASGPEKFKEVYKQQRMTWTAFKIHYLRKERNLQNETEQIGYIDDCLREIAKLDQAVERELYLKQLADEFELTIETLKQQLQQSLKNSQKSRQMASYNEPPIDDSFMGMMPQEGAEMLFSFEQPAQKLSAHTISEQQLMKAMMESRDNFLLIKQLLGDTTFYHDNYEALYTYLIGYFAEGNDADPTKFMDSVPDAAMKGLISSLEMVISPDEQGKPQFEDYIRSLKRYKLEQKKKELEQELATYNRENDNENEIRVMLEIVQLNRQLNSGQLD
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: Y869_STAS1
Sequence: MTTTGYIGTYTKKEGKGVYRFQLDEETGKITEVKTGYELEASTYVNQHNHFLYAVTKEGDDCGIASLKIESDGTLSLINKCLASTAGNGCYVSASPDGKYIFEAIYGAGLARIYEANPETGEIVRLIQELAHDYPTGPSERQEQPHVHYLNTTPDEKYVVAMDLGTDKVITYEYGDDGLKVYDTIEFEPGDGPRHITFHENGKHAYVVHELSNIVSTLKYENGHFTEIERHLTIPENFDGDTKLAAVRISHDQNFLYISNRGHDSLAIFKVGDEGATISLVDIVKSGGEFPRDFNITESDDYLVCAHQEGDYALTVFKRDKVTGNIEIVDNQETAPEGVCVQFLR
What are the official names of this protein?
Uncharacterized protein SSP0869.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: EMRE_DROME
Sequence: MIVPRLALPISLALQRVSRRVAEHPHNLRILQRHMSSVYFRSGAIKPKPEEMPFGLLAIFCAVIPGLFVGATISKNVANFLEENDLFVPADDDDDED
What is the function of this protein?
Essential regulatory subunit of the mitochondrial calcium uniporter MCU channel, a protein that mediates calcium uptake into mitochondria.
What are the official names of this protein?
Essential MCU regulator, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SMDT1/EMRE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NRG1_CHICK
Sequence: MWATSEGPLQYSLAPTQTDVNSSYNTVPPKLKEMKNQEVAVGQKLVLRCETTSEYPALRFKWLKNGKEITKKNRPENVKIPKKQKKYSELHIYRATLADAGEYACRVSSKLGNDSTKASVIITDTNATSTSTTGTSHLTKCDIKQKAFCVNGGECYMVKDLPNPPRYLCRCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNVMNMANGPHHPNPPPDNVQLVNQYVSKNIISSERVVERETETSFSTSHYTSTTHHSMTVTQTPSHSWSNGHTESILSESHSVLVSSSVENSRHTSPTGPRGRLNGIGGPREGNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPTSPKSPPSEMSPPVSSLTISIPSVAVSPFMDEERPLLLVTPPRLREKYDNHLQQFNSFHNNPTHESNSLPPSPLRIVEDEEYETTQEYEPAQEPPKKLTNSRRVKRTKPNGHISSRVEVDSDTSSQSTSSESETEDERIGEDTPFLSIQNPMATSLEPAAAYRLAENRTNPANRFSTPEELQARLSSVIANQDPIAV
What is the function of this protein?
Direct ligand for the ERBB tyrosine kinase receptors.  The multiple isoforms perform diverse functions: cysteine-rich domain containing isoforms (isoform 2-isoform 4) probably regulate the expression of nicotinic acetylcholine receptors at developing interneuronal synapses.  Isoform Ig-NRG is required for the initial induction and/or maintenance of the mature levels of acetylcholine receptors at neuromuscular synapses (PubMed:8453670, PubMed:9491987).  Binds to ERBB3 and integrins to form a complex which is essential for NRG1-ERBB signaling (By similarity).
What are the official names of this protein?
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-1]: Secreted.
Protein: ENGB_SALA4
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDCGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVVDGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIQWAVESNIQVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVEAFSSLKKQGVDKLRQKLDSWFSELAPVEEIQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SKAP2_DANRE
Sequence: MRSVPEDFTTLISDLETFLTDVLKGENLSKKAKEKKDAFIKRIKDVKTSYAQEFKDRRDEEFPEPDEADTNDGGSLHSEQTDRDDENAYDGVQQSPPVAAQDLQAVLKSGYLEKRRKDHSFFGNEWQKRWCALNNSIFYYYGSEKDKQQKGEFNIVGYTVKMNNTLRKDAKRDCCFEVSAPDKRVYQFCAASEKEAKEWVEHIDFLIKDLGGIIPEDEEEYDDCLSMSQSEVAILPDDDIYEELPEEDVPQPSKPKVTLVNKPPPPATPVTAAVNKSTDYANYFQGLWDCIGDQPDELSFKRGDTIYILSKEYDMFGWWVGEMKGVIGIVPKEYLLELYVL
What is the function of this protein?
May be involved in B-cell and macrophage adhesion processes.  May play a role in src signaling pathway (By similarity).
What are the official names of this protein?
Src kinase-associated phosphoprotein 2, Src family-associated phosphoprotein 2.
What is the protein family that this protein belongs to?
Belongs to the SKAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_NEIMB
Sequence: MPDYIRISRAADSLRDIKITPHFLPHTDGSCLIECGNTKVICTASIDENVPPFLRGKNQGWVTAEYGMLPASTASRMLREASAGKQSGRTQEIQRLIGRSLRAVVDMEKLGERQILIDCDVIQADGGTRTASITGAFVALQIAVGKLVSDGILSENPIREAVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNIVMTASGKIIEIQGTAEDAPFSLDELGKLVALAQKGIGELLQHQQNALSAA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PSRP_SALG2
Sequence: MDNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKQDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLTLPTSLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: PYRR_MYCTU
Sequence: MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRVVLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPLASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: IFNA5_MOUSE
Sequence: MARLCAFLMVLPVLSYWPTCSLGCDLPQTHNLRNKRALTLLVKMRRLSPLSCLKDRKDFGFPQEKVGAQQIQEAQAIPVLSELTQQVLNIFTSKDSSAAWNATLLDSFCNEVHQQLNDLKACVMQQVGVQESPLTQEDSLLAVRKYFHRITVYLREKKHSPCAWEVVRAEVWRALSSSVNLLARLSKEE
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-5, IFN-alpha-5.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPEL_STRS2
Sequence: MLDLIATRRALHQIPELGMEEFKTHAFLMETIEGLLQDCSFAQVRTWKTGILVYLTGSAPEKTIGWRADIDGLPIVEETGLDFKSLHPDRMHACGHDFHMTIALGLLEKMAEQQPRNNLLFLFQPAEENLAGGMLMYEAGAFGDWLPDEFYGLHVRPDLKVGQMATNRATLFAGTCEVKIRFTGKGGHAAFPYTANDALVAASYFVTQVQSVVSRNVDPIEGAVVTFGSMHAGTTNNVIAETAFLHGTIRALTQNMSLLVQKRVREVAEGIALSFGVDLEIELNPSGYLPVENNPQLADELMTYFDGIDGVEMIDCPPAMTGEDFGYLLNKVPGVMFWLGVDTPYPLHNPRLSPKEEVLPFAVDKLSDFLKMKAN
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: YCIB_PSYIN
Sequence: MKQFFEFIPLIIFFVVFKTTDIYIATGALIVSMGLMLAFNYYKDGKVEKMQVITFGMVLVFGTLTIVLHDDVFIKWKVTVVYALFSLALLVSQFFYKKPIIKQMLSKEINLPANIWNNLNMAWALLFAVLSAVNVYVAFSLSQETWVNFKVFGLLAITLAFTLLSGLYIYKYLPATAEKKISANKNPEE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTSQ_MYCLB
Sequence: MTETDEGAPVNHSATMWAVVGVPPVCGGQPGDSGVVAGTSRALVDAAIIAPVTTLTRDEPAQYDRYEFEGPRRRARRERAERRAAQACAIAIEEARREAKHRIHRQMSSEANSPKPVARGVVRGLKTLFATVMFSIAGFGLGLALYVTPAMSVRNIVVTGIETVTREEVLDAAGVQLGTPLLQINTNQVADQVAAIRRVASARAQRQYPSALRITIVERVPVVVKDFPDGPHLFDCDGVDFATAPPPPALPYIDVGHPGPIDPATKAALVVLLALRPEVVSQVARIAAPSVSSITLILTDGRAVIWGSTDRAEEKAEKLAALLTQPGRTYDVSSPDLPTVK
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: MED21_ASPFU
Sequence: MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPAIPPPDVPDAAPALAKIPKNSTAPPVPAGAPVPALSQASPPAQNPAHGAAGAGTSVGEGAQTPGPAAGAGADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEGELRQVEEERELKMRELKRLRRTLENVLTAVETGLYGDRELLEKYA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL332_STRT2
Sequence: MRVKINLKCSECGSLNYLTSKNKQNHPEKIQVPKFCPKDRKVTLHVES
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SAT_ECOL6
Sequence: MNKIYSLKYSAATGGLIAVSELAKRVSGKTNRKLVATMLSLAVAGTVNAANIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGDKFSFHNLSIPDFSGAAASGAATAIGGSYSVTVAHNKKNPQAAETQVYAQSSYRVVDRRNSNDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFINGESKISTNSAYSHDLLSASLFEVTQWDSYGMMIYKNDKTFRNLEIFGDSGSGAYLYDNKLEKWVLVGTTHGIASVNGDQLTWITKYNDKLVSELKDTYSHKINLNGNNVTIKNTDITLHQNNADTTGTQEKITKDKDIVFTNGGDVLFKDNLDFGSGGIIFDEGHEYNINGQGFTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKKQGANIKIGEGNVILNEEGTFNNIYLASGNGKVILNKDNSLGNDQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAINNEDSYIYHGNINGNIKLTHNINSQDKKTNAKLILDGSVNTKNDVEVSNASLTMQGHATEHAIFRSSANHCSLVFLCGTDWVTVLKETESSYNKKFNSDYKSNNQQTSFDQPDWKTGVFKFDTLHLNNADFSISRNANVEGNISANKSAITIGDKNVYIDNLAGKNITNNGFDFKQTISTNLSIGETKFTGGITAHNSQIAIGDQAVVTLNGATFLDNTPISIDKGAKVIAQNSMFTTKGIDISGELTMMGIPEQNSKTVTPGLHYAADGFRLSGGNANFIARNMASVTGNIYADDAATITLGQPETETPTISSAYQAWAETLLYGFDTAYRGAITAPKATVSMNNAIWHLNSQSSINRLETKDSMVRFTGDNGKFTTLTVNNLTIDDSAFVLRANLAQADQLVVNKSLSGKNNLLLVDFIEKNGNSNGLNIDLVSAPKGTAVDVFKATTRSIGFSDVTPVIEQKNDTDKATWTLIGYKSVANADAAKKATLLMSGGYKAFLAEVNNLNKRMGDLRDINGESGAWARIISGTGSAGGGFSDNYTHVQVGADNKHELDGLDLFTGVTMTYTDSHAGSDAFSGETKSVGAGLYASAMFESGAYIDLIGKYVHHDNEYTATFAGLGTRDYSSHSWYAGAEVGYRYHVTDSAWIEPQAELVYGAVSGKQFSWKDQGMNLTMKDKDFNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLFANGETVLRDASGEKRIKGEKDGRMLMNVGLNAEIRDNLRFGLEFEKSAFGKYNVDNAINANFRYSF
What is the function of this protein?
Shows serine protease activity and displays cytophatic activity, including elongation, rounding, and detachment of a proportion of the cells from monolayer in culture.  Triggers vacuolation within the cytoplasm of the human bladder and kidney cells.
What are the official names of this protein?
Serine protease sat autotransporter.
What are the subcellular locations of this protein?
[Serine protease sat autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Serine protease sat]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Serine protease sat translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: COMC_METJA
Sequence: MILKPENEKKLIIDVLKKFGVPEEDAKITADVFVDADLKGFTSHGIGRFPQYITALKLGNINPKPDIKIVKESPATAVIDGDLGLGQVVGKKAMELAIKKAKNVGVGVVATRNANHFGIAGYYSELAMNQDMIGITITNTEPAMAPFGGKEKILGTNPIAIAFKGNKYKFSLDMATASIARGKILEALRKKIKIPEGCAVDKDGKPTTDPAKALEGCILPFGGPKGYGLALAIEMLSAIGGAEVGTKVKGTANPEERCTKGDLFIAINPEFFMGKEEFKRKVDELLDEIKNSEPAEGFEILIPGEIEERNKMKRKDGFEIDKNLYNQLKEICNELGLNIEDYIE
What is the function of this protein?
Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction.  Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate.  Involved in the biosynthesis of both coenzyme M (with (R)-sulfolactate) and methanopterin (with alpha-ketoglutarate).
What are the official names of this protein?
L-sulfolactate dehydrogenase, (R)-2-hydroxyacid dehydrogenase, (R)-sulfolactate dehydrogenase, L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHRSX_MOUSE
Sequence: MSTLRALRAVLCVYAVGIAVALAQLLRRLRGDFRPPVLPPQPGRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHRGQEVVSSIRAEMGSDRAHFLPLDLASLASVRGFARDFQALGLPLHLLVNNAGVMLEPRAETEDGFERHLGVNFLGHFLLTLLLLPALRASGAEGRGSRVVTVGSATHYVGTVDMADLHGRHAYSPYAAYAQSKLALALFALQLQRILDARGDPVTSNMADPGVVDTELYRHAGWVLRTAKRFLGWLVFKSPEEGAWTLVYAAAAPELEGVGGRYLRDEAEAEPLGTARDQELQRRLWAEGLRLTGAGGGDSDGVAW
What is the function of this protein?
Involved in the positive regulation of starvation-induced autophagy.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member on chromosome X homolog, DHRSXY, SCAD family protein.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in a non-classical form. A signal peptide sequence at position 1-23 is predicted.
Protein: S6A12_RABIT
Sequence: MDTKLAVHEDAPPLVSWVPEEGEKLEQEGEDQAKDRGQWTNKMEFVLSVAGEIIGLSNVWRFPYLCYKNGGGAFFVPYFIFFFSCGIPVFFLEVALGQYTSQGSVTAWKKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCTNSWNTEYCQHALNHSGAGIGSSTENFTSPVMEFWERRVLGITAGIHDLGALRWELALCLLLAWIVCYFCIWKGVKYTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIVYYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSVLGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCMECLVTASVDMFPRQLRKSGRRELLILAIAVLCYLIGLLLVTEGGMYIFQLFDYYACSGICLLFLSVFEVVSISWVYGADRFYDNIQDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYSPLRYNNVYVYPAWGYCVGWFLAFSSMACVPLCIVIALLKAQGSFTKRLRQLITPDPSLPQPTQQLRLDSGPGQDRRPSPAKEGLVTVEKETHL
What is the function of this protein?
Transports betaine and GABA.  May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent betaine transporter, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PQIB_ECOLI
Sequence: MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPEVTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDTVFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRVILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRFWKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKSIQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYRIPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNTPAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRTMKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRLDQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ
What is the function of this protein?
Component of a transport pathway that contributes to membrane integrity (PubMed:27795327).  May directly span the intermembrane space, facilitating the transport of substrates across the periplasm (Probable).
What are the official names of this protein?
Intermembrane transport protein PqiB, Paraquat-inducible protein B.
What is the protein family that this protein belongs to?
Belongs to the PqiB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: KLH26_HUMAN
Sequence: MAESGGSSGGAGGGGAFGAGPGPERPNSTADKNGALKCTFSAPSHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASLRESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSPRTAVRSDVPSLVTFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLDNFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGGRNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGAASGGRLYISGGYGISVEDKKALHCYDPVADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTSVSPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTDTDEWERDLHFPESFAGIACAPVLLPRAGTRR
What are the official names of this protein?
Kelch-like protein 26.
Protein: CAMT1_PETHY
Sequence: MAENGAAVQENQNVIRHQEVGHKSLLQSDALYQYILETSVYPREPESMKELRELTAKHPWNLMTTSADEGQFLNMLLKLINAKNTMEIGVYTGYSLLATALAIPHDGKILAMDINRENYEIGLPVIEKAGVAHKIDFREGPALPVLDQLVEDKNNHGTYDFIFVDADKDNYINYHKRIIDLVKVGGLIGYDNTLWNGSLVAPADTPMRKYVRYYRDFILELNKALAADPRIEICMLPVGDGITLGRRIS
What is the function of this protein?
Involved in the production of floral volatile phenylpropanoids in flowers of fragrant cultivars (e. g.  cv.  Mitchell and cv.  V26) from cinnamic acid, a common precursor with the anthocyanin biosynthesis pathway involved in flower pigmentation (PubMed:26620524).  Methylates caffeoyl-CoA to feruloyl-CoA, also able to methylate 5-hydroxyferuloyl-CoA (PubMed:26620524).
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase 1, PhCCoAOMT1, 5-hydroxyferuloyl-CoA O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.