PharMolix/UniProtQA huggingface dataset:
Protein: PTFC_BACSU
Sequence: MSSLQIILLLIIAAITGIASVLDEGQTHRPLVACTLVGLVLGDLKTGIILGGTLELMALGWMNVGLAMAPDTAIASVISTILVITADQGIGEGIAVAVALAAAGQALTIFVRTITVFFIHRADQYAKAGNIKGIEIMHITAMVFQALRVMIPTLIVALISVSAVQAFLGNIPDVITKGLQIGGGIIVVVGYAMVINMMNIPYLKPFFYIGFLLAAFTDFNLVGFGALGLCLALLYQQVMQKQSAHGAVAAASDSGSVAVYDDDDDDLDA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  This system is involved in fructose transport.
What are the official names of this protein?
Fructose permease IIC component, EIIC-Fru, PTS system fructose-specific EIIC component, p28.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TANA_XENLA
Sequence: MEGYLASVSLGEESTQMWSLNKRLEAYLSRVKALEEENELLRKEIHSLRSSKSERCWKKKHHEEMMKLRDALDDGHREMVQAEMVRDSIYEEIEFVKQRCLEEKQAREDAKKELSESKKLLEEETRAQIWLKERLGQLEAELEDILRDHEEEKALMEEEIASFSQRLENFRVAPVAFKPVEVDDYARKLSEIWQGAVEEYKSEVSVLEAGLSESKENLRKVLEENKQNRLLLQSLDKELVSLKMRKEALEDLLSKQWQEQKEEEEKLQRKAEALEQEKQDLRGQIAEVLEDRQQLMHLKMSLSLEVATYRSLLEAESTRIYTDYRGSYTFNDSMLEHNNVRRRQSEDTRKTVSKDHRQSYSKKQIGDKNELQRPSLNNFSTVKSSAVPVRTSPVTKEFQKVSSVLQSQGLKYTKAPQVKEVQTVSTVKSNLETHTFSGDAFRRAQVETRKTDEQVIKKDALGLNDLNKNTGFKEEKDIQKPGFMDHVVSKSVSSTEHKVPEIDPLESALKSLEEDLSSVSSTFNAGQSSNLEAIKDVLGEPICLENLQNEIAFEKESPGTNAAADPIEEVISESVSYQTVHFEKQELSNLLEIENTHENHVQDATQAFNSCEQDGHDRASTLENNEPDVQQYIRTLESNEIKESKIPSDNTEEAEIISKSRKVFLENEYIPVSKDDLTEFTSHLENDSESSQSFDSKLFENKSTEDQLITNLKSNTQENIFQSNQEHLENLEFDSVVPDTVKFMYPQENNLLEEENVYGDGELVQMATDENIINQSSDQLLLSDHSHHEETKTSESIAVEHNRMESEHAEVDKSSEIPVEISENVSVEEIIHEISDVEEDTKQAFEDERVGEQINQNNQESTVDLDGSVYSQEENSQLEEDEVSISEQIEKDFEINEQECLKSDQIREAFDTEEVDHQVVDFMQEQSFEREVGQLNNIKQEVDYLQNYDEDSFQNNDEPQELESCDLQEQKIKLEEENQLSENEGNQNFGGNDIEEFSQQGYDTDEICQETIGNQVSAQLLCESDINQDKLSMEDEEEQNNPETEDNIGLEQESDQENTRSNEGTKFSQEECDVVFKPEDMSDKSEYSGQQEDLDKQVTDFSLNEQANNDLLEKEEVILHHADDQRSVNDEITIDEKLSERIIDNELATVDVNESLAANKEQVDLFTDEYAVDDNVGMQDDDSGQYQTKEDLFVDGNNIIEKIEIQQTSLLNQEICERVDNVDEDISGEAKNESVEMNDVVDLVPEAKVTGDEQISPLQDEKLNLETMEDTKDNDGQLCLEKENETEYIEVTDSPQFATDLSHDAGRELTVDQNSANLQFCENPTKTLIAHHIEYETVADSDLESTEEQVQETERIPFKPEDSKMENENSESEESVDSQEISLNSHKSEEFEISKDYQLEQTLPDVTPLPNLEDEFEDLTEQPDVHEEHQNNDDSGASTFITSVDEDKEREVRESVSKDEESNEEEFGDVLSVDKTSQVEVTTLSGLAQEPSYLGDNEESEDSMENAEILNENPSNDIVDFMVSQMTETKIIIAEQVTEQTEVTLQFDDAPNKLTENLNAREKETYDYESNEENIEFTNENQSASPANDIVDENQSEDSVISDNEGTTSSYEDLPNATSISHVVALEESNISTTEQSSTDTKRMTYEGYEITSLQNVEDNAQETEKEFPSGVPLGQEDSRSEDEELDDEGSEFSFGVNDEKANGEHKDVGEDDETEDMLNGHSQTGYSKIVLTSKKALRWKRMF
What are the official names of this protein?
Tanabin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: CFGA_TACTR
Sequence: MLVLLCCVVLHVGVARICCSHEPKWQLVWSDEFTNGISSDWEFEMGNGLNGWGNNELQYYRRENAQVEGGKLVITAKREDYDGFKYTSARLKTQFDKSWKYGKIEAKMAIPSFRGVWVMFWMSGDNTNYVRWPSSGEIDFIEHRNTNNEKVRGTIHWSTPDGAHAHHNRESNTNGIDYHIYSVEWNSSIVKWFVNGNQYFEVKIQGGVNGKSAFRNKVFVILNMAIGGNWPGFDVADEAFPAKMYIDYVRVYQDASTSSPVGDTSLDGYYFVQNRHSELYLDVTDASNEDGAFLQQWSYSGNENQQFDFEHLENNVYKITNKKSGKSLDVYNFGTENGVRIQQWSYGGARNQQFTVQSVGDGYYKIIPRGSGKLVEVADFSKDAGGKIQQWSDNNQLSGQWKLIKSKSYSKLIQAESYFDSSKVQLEDTSDVGGGKNVKCDNEGAWMAYKDIDFPSSGNYRIEYRVASERAGGKLSLDLNAGSIVLGMLDVPSTGGWQKWTTISHTVNVDSGTYNLGIYVQRASWNINWIKITKIPEQSNLNQGRRNSKLIQAESYFSYSEVQLEDTLDVGGGKNVKCDKEGAWMAYKDIDFPSSGSYRVEYRVASERAGGKLSLDLNAGSIVLGMLDIPSTGGLQKWTTISHIVNVDLGTYNLGIYVQKASWNINWIRITKV
What is the function of this protein?
Component of the heterodimer clotting factor G which may play a role in defense mechanisms against fungi (Probable).  Initiates a (1->3)-beta-glucan-sensing clotting pathway whereby the alpha subunit binds to glucans containing (1->3)-beta linkages, which are components of the fungal cell wall, and the beta subunit catalyzes the activation of proclotting enzyme (PubMed:7822328).
What are the official names of this protein?
Clotting factor G alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: PANB_BACFN
Sequence: MAGYISDDTRKVTTHRLIEMKQRGEKISMLTSYDYTMAQIVDGAGIDVILVGDSASNVMAGNVTTLPITLDQMIYHGKSVVRGVKRAMVVVDMPFGSYQGNEMEGLASAIRIMKESHADALKLEGGEEIIDTVKRILSAGIPVMGHLGLMPQSINKYGTYTVRAKDDAEAEKLIRDAHLLEEAGCFGLVLEKIPAALASRVASELTIPVIGIGAGGDVDGQVLVIQDMLGMNNGFRPRFLRRYADLYTVMTDAISHYVSDVKNCDFPNEKEQY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLF11_MOUSE
Sequence: MSWANESITGEFVLLGFSDQPWLEFPLFVVFLTSYIVTIFGNLNIILVSHLDPKLHTPMYFFLTNLSVIDLCYITCTVPQMLVNLRSIRKVISFGGCVVQLFMFLALGATECVLLPVMSFDRFVAICRPLHYSVIMHQRLCLQLAAVSWIIGFGNSVWLSILTLQLPRCGHYVIDHFLCEVPALLKLSCVDVTANEAELFFVSVFFHLTPLSLILTSYAFIARAILKIQSAEGRQKAFGTCSSHLIVVSLFYGTALSVYFLPPSPHSKNRRKMVPLFYGIIAPMLNPLIYTLRNKEVKDAFKRLIKRVFLSKN
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 11, Odorant receptor M49, Olfactory receptor 256-11.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABP7_CHICK
Sequence: MVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMTLTFGDVVAVRHYEKA
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, brain, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7, Fatty acid-binding protein, retina, R-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLBT_RHIL3
Sequence: MKSTLRISLKAGERIFINGAVLRVDRKVALEFLNDVTFLLENHVLQPEGATTPLRQLYFIAQMILINPEGKDHSTALFRKSITMLLSCFRNEEILAELKRIDALVSTGRAFDALKAIRGLYAIEDNILNNHEMPPTMVEQIRREIAPWR
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.
Protein: NCBP2_CHICK
Sequence: MSGLLHTTLSGLNSDSYCEISRYRDQHFRGSKKLQEKFLKISSTLYVGNLSFYTTEEQIQELFSKCGDVKRIVMGLDKIKKTPCGFCFVEYYTRADAEHAMRFINGTRLDDRIVRTDWDAGFKEGRQYGRGKTGGQVRDEYRTDYDVGRGGFGKIIQMQKANQQPAVY
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between UPF1 and UPF2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with SRRT/ARS2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of PARN, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS6_STAHJ
Sequence: MRTYEIMYVVRPNIEEDAKKAVVERFNGILASEGSEVLEEKDWGKRRLAYEIEDFKEGFYNIVRIKTDNNRATDEFQRLAKISDDIIRYIVIREDQDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: REV_JEMBR
Sequence: MMEEGRKEEPEERGEKSTMRDLLQRAVDKGHLTAREALDRWTLEDHGPPVHHVKLGRSNTVSIAECARGYRPCRGRRPARRPPIRRHPSFWGTLRGLVSEAQRRQEDRMSDLENRMAELEERFEDLALVDSGGKNPAAPAQSVSPPSSNPFAYSLSHFSKSKRVDCGEKGNRWGRPGAFPGAGISELDWIESGDGGDERPKGGRYPRGGNTPS
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: CLPX_RICPU
Sequence: MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSIPTPQKICGILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIASEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNILFICGGAFMGIDSIITSRTNHSSIGFAANVNMDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITILTKPKNAIVKQYQKQFELDDAELVIDDSALETIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKRQRVTITKEVVNGLVEPIMTSLISTKSNKKQPIIADIPA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: GUAA_SALPC
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEERFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FENR_BURVG
Sequence: MTSSENSSVSNPLRTDVLIVGAGPVGLFAAFEAGVIGLSCQIVDGIERPGGQCIELYPDKPIYDIPAVPSCTARDLVDRLVEQCRPFNPPMHLGQRIERLDPLEGGRWLARTDKGHTFDAAAILIAAGNGAFVPQRLALDEAARLEGRYVHYRVSDMNGLAGTNVVVAGGGDSALDWALALRSVARHVTLVHRRSGFSATDSSVARLRQAVAAGEMDFVVGTIARLNSPVGPLESIEVRQIGGSVCLDADQLLVLYGLVADLGPIVNWGIAIQAGRIVVDTSYYESSRPGIFAAGDIACYPNKQKLILCGFHEASLALRKAYNYAFPDKKRVHVHSSYDAKLAERVAAVHP
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ZNF7_PONAB
Sequence: MEVVTFGDVAVHFSREEWQCLDPGQRALYREVMLENHSSVAGLAGFLVFKPELISRLEQGEEPWVLDLQGAEGTEAPRTSKTDSTIRTENEQACEDMDILKSESYGTVVRISPQDFPQNPGFGDVSDSEVWLDSHLGSPGLKVTGFTFQNNCLNEETVVPKTFTKDAPQGCKELGSSGLDCQPLESQGESAEGMSQRCEECGKGIRATSDIALHWEINTQKISRCQECQKKLSDCLQGKHTNNCHGEKPYECAECGKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNECGKAFSQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSIFVSRKKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCNDCGKAFNRSSRLTQHQKIHMG
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 7.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDD_CROS8
Sequence: MHPRFETAFAQLPAALQAALAPLIADTYFPAMLSAEQVADVRRQSGLDDDALAFALLPLAAACAQTEISHFNVGAVARGLSGNLYFGGNMEFRGAAMQQTIHAEQSAITHAWMRGETGLAAITVNYTPCGHCRQFMNELNSGLTLRINLPGRAPSQLGDYLPDAFGPRDLDIKTLIFDTENHGYALKGDALTQAAIAAANRSHAPYSQSPSGLAIETRDGEIFTGSYAENAAFNPSLPPLQAALNLMSLNGYAWADIKRVALAERDDATIVQRDATAATLKALGFTNLELVTLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RL16_SHEFN
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHVKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMDGVPESLAREAFALASAKLPLKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GCST_BACLD
Sequence: MLKRTPLFDLYKEYGGKTIDFGGWELPVQFSSIKEEHEAVRTKAGLFDVSHMGEVEITGTDSLPFLQKLLTNDVSTLKEGGAQYTAMCYEDGGTIDDLLVYKKAANVYMLVINAANIDKDVDWMNKHIKGDVSVRNVSDEIALLALQGPKAEAILKQVADHDLAELKPFMFRDDAAVGSVQALVSRTGYTGEDGFEIYCRNEDAACIWKLLLETGKDSGLVPCGLGARDTLRFEAKLPLYGQELSKDITPIEAGIGFAVKTNKASDFIGKAVLASQKEHGADRKLVGLEMIDKGIPRHGYAVYYQGEQAGEVTTGTQSPTLKKNVGLALLKKEACALDTVVEVEIRNKRLKAKIVKTPFYKRQP
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: DNLJ_PETMO
Sequence: MDIPKNIKERYEKLKAEIEEHNYRYYVLADPIISDQEYDKLFKELVELEKKYPELKTPDSPTQRIGGIVVEGFNKVNHLIPMLSLDNTYNEEEILDFHKRVLKNLSLNHVEYFCELKIDGVSVALRYTDGVLTQAITRGDGTTGEDITQNVKTIPSIPLRLRENLTIEVRGEIYMPKKEFVRINSEREEKGLPVFANPRNATAGTLKLLDSTEVAKRKLSSFMYYVIFPQNYNLETQEEAINFLKEVGFRINPNYKNAQDIGQVIEFWKEWNRRRKELEYEVDGIVVKVNSFELQRLLGETARSPRWAIAFKFEAEQKETKLKAIKLQVGSTGIITPVAEFDPIQLEGTIVKRASLHNFDYLKERDIREGDYVLIEKAGGIIPQVIGPVKEKRTGEEKIIRPPEKCPVCGGKVGKIKSSEVAIRCLNPSCPEKLLRTLENFVSRNAMNIQGLGPKILKRMVDAGLLKDIADLYYLNEQKIRSLGEGIGDKTVENILTQIEQSKNRELDRLINALGIPNVGSKTAKDLANHFKNLDSLIDAKFDELVEIEGIGEDIANAIIKFFSQEEVKKIVKKLKDAGVNMGKKEEEKLEGPLKGLVICQTGALSKMTRQEFAEYVESKGGTFSENVTKKTNILVVGENPGSKLDKAQSYGITIMSEEEFFDKYGES
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TSNAX_MACFA
Sequence: MSNKEGSGGFRKRKHDNFPHNQRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLSRDITVESKRTIFLLHRITSAPDMEDILTESEIKLDGVRQKIFQVAQELSGEDMHQFHRAITTGLQEYVEAVSFQHFIKTRSLISMDEINKQLIFTTDDNGKENKTPSSDTQDEQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDIDTPFEVSQFLRQVYDGFSFIGNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLADVSSVKTEMIDQEEGIS
What is the function of this protein?
Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC).  Possible role in spermatogenesis (By similarity).
What are the official names of this protein?
Translin-associated protein X, Translin-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the translin family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Golgi apparatus. Nucleus. Note=Expressed in the cytoplasm in the presence of TSN. Accumulate in the Golgi complex of mid-late pachytene spermatocytes (By similarity).
Protein: LEUD_METS5
Sequence: MIVEGPVLKYGDKIDTDIIIPARHLKYTDPAYLAQHAMEPLDPEFYKKASKGVVIVAGKVFGMGSSREQAAIALKAAGVKAVIAESFARIFYRNCINNGLPLITLPNATKEINEGDVVKINVETGEITVNGRVLKGKGITGMALDILKSGGIMEYLKKVSA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: TIRC_DICDI
Sequence: MNSNIIKSIDIIPNNNNNNNNSVSTVNTNSSVINNNNNNNYNNNSISNGNNERIKVFIVHGHNNIVREKVSKFLFEMGFEPILLFEKPNNGQTIIEKLEKEISNCKFGIVIMSPDNKAFTKKDSNSDYVEIAYPRLNVVFEFGYLIGKFGRSNVIYLSVPYNGKSQNYDLPSDLLGYVWINYTEDLKELENEINFGNYKKL
What are the official names of this protein?
Protein tirC, TIR domain-containing protein C.
Protein: ASSY_PSEAE
Sequence: MADVKKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKARAMGVKEIYIDDLREEFVRDFVYPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHGIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWKWTASPENAPDTPTYIELTYRKGDIVAIDGKDMTPAEVLTELNRVGGINGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVVVVGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRTLS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL173_YEAST
Sequence: MHTNSPLRADNQDLETQPLLRPNTEESQLLNDEVRINVANETLIKSRWRSIKCLIIYLLGIVLLSFFGVSIVQYIRGHVPPTDVIEKNLVQVTNFKLVEFQLDGWKDNMGSDLNNDTGKYLQVSIHSQIWFDYDKWPGTENDSDARSQRDWIRYINEKVLKTICIDLNNVTTFDGDLVFKNKLGDVVGMEPICFNLAHRQINNLQFKILVKPSIWKIVKVLKKFWNRDFESLNIKSNLDMTIFKRKFGTRFNLLKLNDEILDWKDIIDWEKISATPLRMIQNMIDGISLQGFTLRDSSSDGFHADMRLNPITILGGVDWLHLPPGTSIPFINWEIKLPDCNGEPAIAIPTLSCFNEPINLHHDKDNIVVCLQNEIEGPLPDELLYQECPQNSLTPMSQIVNAVLNQNETVTFAARGHVLEDGIDNNSLIPADMLEDIFQEASFIPITTNATFNSSELIQEFQINDLQLRWAARKKLSLVGTFLGFFDLSFYETHQQDRVRIDTIRGQIDLYHNDINFLNLPMKQWINSSSHILHDEDTGNTQMKLQFDLENDDMEVVNSLELTRTLNEILFQGFTVIHFNATIDASLTTALGPWVLTGLAGEGDTLVT
What are the official names of this protein?
Putative uncharacterized protein YLR173W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FABZ_PROMS
Sequence: MEKKLSSENNQLSSENILGLLPHRYPFALVDKVIENIPGERAVAVKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGIIVTQMQNLPKGLFVFAGINNVKFRKPVVPGDQLIISCDLLSIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_ECO45
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRLPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPVEFHHLLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMPA_DICDI
Sequence: MVKRGCCHRKMVNHKGCLVSGIFLAVIGAVLFILAFALLPHLINQTTQNAVIQAVIVDSTSSQRYNDWAGQQSIENYYQQYFYAWNLTNPNEFLNGSIPIFETVGPFNYKYEFNFSNVTFQDGGNLATYTQSKSFIYQSDMSPNDPNEIMITNINPAYLGLMFQLAPNAELLDNMPAENLLIALSGCGQMRLFLEYLSSDNFTNIVYFTQNPKLYQEQYLNILKSLNGDEQYFYQQWANATSIPQKGNGWYGMLVSSVNNNNESSNISILSAKLLFNSSNENSILNQEIGSTLWINALLGDKTSITVLTSELQLTVDQIDMILNWWLNDFSKVYTESYVNEICDIPDISMLGVCQFVTGNALNGRSISNYTFLTQPFDQGPIEIPLLYQSIGIDVKLSVSVQQAYKSLFNESDSNSILNLNGLVNFLTASKSFDTFKQYNVTLFDAIKIIGYATAELYEQYNKPTILGLYEKYGGLIVTRSMDDWLWNCQDGILDYLGVDQPCALQQNNTVNKPSTIFTGQQDLSMTNQIFEFQEQTFLTCWNGSVQVEGFTESGQFPPLQSDPPQTMTLFEENVIRPVQLELSGDSQVQGIDTKRYYLVNNSFPISTTFKTTIPGFANLTDIQNLPIYVSLWDMYEVPPQYSSNNLQGLNQTYQSAQVPLDLEPITGNALYYNLKLQINLAIPEFSNWFSSNSTFKNMKSNVFYPILKIGQTATPSQSNIDLLNSQFKLIKILGFVPVIVVSIIGGIILIAGISMFAFGFKKLRQQKQQGYQAIINNE
What is the function of this protein?
May act as a lysosomal receptor (By similarity).  May be involved in macropinocytosis and fluid phase exocytosis.  Binds to the anionic phospholipid phosphoinositol 4,5-bisphosphate, but not to phosphatidylcholine and only weakly to phosphatidylserine.
What are the official names of this protein?
Lysosome membrane protein 2-A, Lysosome membrane protein II-1, LIMP II-1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Note=Localizes to membranes of endolysosomal vesicles and macropinosomes.