PharMolix/UniProtQA huggingface dataset:
Protein: DTX45_ARATH
Sequence: MESSRVVVGGGLPLANRRNSSFAKPKIQQGTFLPLSRINNVSAPQKCSLHTNPNPMFPFVTRRKSQTNPDCGVVKLGEEDDSCSSLDKLPEVNGVHTGVARPVDIKRELVMLSLPAIAGQAIDPLTLLMETAYIGRLGSVELGSAGVSMAIFNTISKLFNIPLLSVATSFVAEDIAKIAAQDLASEDSQSDIPSQGLPERKQLSSVSTALVLAIGIGIFEALALSLASGPFLRLMGIQSMSEMFIPARQFLVLRALGAPAYVVSLALQGIFRGFKDTKTPVYCLGIGNFLAVFLFPLFIYKFRMGVAGAAISSVISQYTVAILMLILLNKRVILLPPKIGSLKFGDYLKSGGFVLGRTLSVLVTMTVATSMAARQGVFAMAAHQICMQVWLAVSLLTDALASSGQALIASSASKRDFEGVKEVTTFVLKIGVVTGIALAIVLGMSFSSIAGLFSKDPEVLRIVRKGVLFVAATQPITALAFIFDGLHYGMSDFPYAACSMMVVGGISSAFMLYAPAGLGLSGVWVGLSMFMGLRMVAGFSRLMWRKGPWWFMHTSDKRLA
What are the official names of this protein?
Protein DETOXIFICATION 45, chloroplastic, AtDTX45, Multidrug and toxic compound extrusion protein 45, MATE protein 45.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: D19L2_MOUSE
Sequence: MVGPTRSKLREGSSDRPQSSCTGQARRRWSAATMEPQQERSAPQERTKWSLLQHFLLGGRKLPSGARNYAARRIQSLNAQNYFQLEEVAKLLLLNRFQFLFTLLDHFREKVQALQMHRFSHRTLFGLAIFVGILHWLHLITLFENDHHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLVINTVKRFHLYPEVVIAYWYRTIIGIMNLFGIETKTCWNVTRMEPLNEVQSCEGLGDPACFYIGVIFILNGLMMGLFFIYSTYLSGSQLGGLITVACYFFNHGEATRVMWTPPLRESFSYPFLVLQMYILTIILRTSTVHKKHYMALCFSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYVNMSSVALCFILMFGNSMYLSSYYSSCLLVTWAIMQKKSKIQKLGGTELQFWLIQGCFWWCGTIILKFLTSKICGVSDHIRLSDLIAARILRYTDFDTLIYTCAPEFDFMEQATPLRYIKTLLLPLILVITYLIFKKIVRDIMCVLYTNTYVRKQLLDNAELIFHTLQLLAFTGLAILIMRLKLFLTPHMCIMASLICSQRLFGWLFCRIHFENVVFGILTMMSIQGCANLHNQWSIMGEFTNLPQEELIHWIKHSTRPDAVFAGAMPTMASIKLSTLRPIVNHPHYEDADLRARTKIVYSVYSRKSAVEVRNNLLKLHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSILLKDSRPYFTTVFQNSMYRVLKIN
What is the function of this protein?
Required during spermatogenesis for sperm head elongation and acrosome formation.  Also plays a role in acrosome attachment to the nuclear envelope.
What are the official names of this protein?
Probable C-mannosyltransferase DPY19L2, Dpy-19-like protein 2, Protein dpy-19 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the dpy-19 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein. Note=Restricted to the inner nuclear membrane facing the acrosomal vesicle. The N- and C-termini are oriented towards the nucleoplasm (PubMed:22764053). Colocalizes with FAM209 at the inner nuclear membrane (PubMed:34471926).
Protein: CB2A_SPIOL
Sequence: MASSTMALSSPSLAGKAVKLGPTASEIIGEGRITMRKTAGKPKTVQSSSPWYGPDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWACQVILMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWNFATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein, chloroplastic, LHCII type I CAB, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: HMOX2_MACFA
Sequence: MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPTFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAKKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAGEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGMALAAGLLAWYYM
What is the function of this protein?
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin.  Biliverdin is subsequently converted to bilirubin by biliverdin reductase.  Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.  Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
What are the official names of this protein?
Heme oxygenase 2, HO-2.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: CA122_MOUSE
Sequence: MEWGPGAGWSRGEAAGVDRGKAGLGLGGRPPPQPPRDERAQQLLDAVEQRQRQLLDTIAACEEMLRQLGRRRPEPAGGGNGSAKSGAPPQPSVSARGGLPKDAGDGASES
What are the official names of this protein?
Uncharacterized protein C1orf122 homolog.
Protein: GPDA_PSEF5
Sequence: MTQQRPIAVLGGGSFGTAVANLLAENGHRVRQWMRDPEQAEAIRVNRENPRYLKGIKIHPAVEPVTDLLATLNDSDLCFVALPSSALRSVLAPHAELLRGKLLVSLTKGIEAQTFKLMSEILQDIAPQARIGVLSGPNLAREVAEHALTATVVASEDEELCQRVQAALHGRTFRVYASADRFGVELGGALKNVYAIIAGMAVALGMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGFALGQGLSLEEAVTRLGEVAEGVNTLKVLKVKAQELGVYMPLVAGLHAILFEGRTLNQVIELLMRGEPKTDVDFISTSGFN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_YERPY
Sequence: MALLDFFLSRKKPTANIAKERLQIIVAERRRGDSEPHYLPDLKRDILAVICKYIQIDPEMLHVQFEQKGDDISVLELNVTLPETEETPK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MAIP1_BOVIN
Sequence: MALAVRLLPRLLLSRPLPGWAARLRTLSSAEVKRPLSGLCYLCRRRLGSGAAPFPRVSWASAALALSARGPQRPLLSPLEVASTLPTFPSCPRRTYSTEEQPQQRQKTKMIILGFSNPINWVRTRIYSFLIWAYFDQEFSITEFSEGAKQAFAHVSKLLSQCKFDLLEELVAKETLHVLKEKVTSLPDNHKNALAADIDEIVYTSTGDISIYYDEKGRKFVNILMCFWYLTSANIPSEAISGARVFQVKLGDQNVETKQLLSASYEFQREFTQGVKPDWTIARIEHPKLLE
What is the function of this protein?
Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation.  Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB).
What are the official names of this protein?
m-AAA protease-interacting protein 1, mitochondrial, Matrix AAA peptidase-interacting protein 1.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IXTPA_CHLTB
Sequence: MKILIASSHGYKVRETKAFLKKLGEFDIFSLVDYPSYQPPKETGETPEENAIQKGLFAAQTFRCWTIADDSMLIIPALGGLPGKLSASFAGEQANDKDHRKKLLENMRLLENTIDRSAYFECCVALISPFGKIFKAHASCEGTIAFEERGSSGFGYDPLFVKHDYKQTYAELPEAIKNQVSHRAKALVKLQPYVETVLANHLLAGKESL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: HEBP2_HUMAN
Sequence: MAEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYNSPVKLLNRNNEVWLIQKNEPTKENE
What is the function of this protein?
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
What are the official names of this protein?
Heme-binding protein 2, Placental protein 23, PP23, Protein SOUL.
What is the protein family that this protein belongs to?
Belongs to the HEBP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion.
Protein: RLUD_NITEU
Sequence: MMNRLINEQDGRNYSAKPDSSAAGSQENENTIELTVPDNLAGLRLDQALAQLLPQWSRSRLQGWIEQKCVSVDSAAATCKQKVWGGESIRVIAGQTENDQSHQAEAIPLKILFEDDHLIIIDKPAGLVVHPGNGNWHGTLLNALLNHAPQLSQVPRAGIVHRLDKDTTGLLVVAKTIEAQFDLARQLQQRTVKRHYLALVLGKLEKDGVVDAPIGRHPIHRTRMAVVQNGKPARTHYRVLEKFTASTLLHCSLETGRTHQIRVHLLSIGHPLAGDPVYGRTSPDPSTADAVVRLPRQALHAWQLELTHPHSGQILLWESPLPDDMAALLQAIRNLPHSSVSRPL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: CSK1_CAEEL
Sequence: MSNGNSYNHHHQFPMSIPISCSSHSIQSQSRMNTLNANRDLLSPGNDVIVTRTVSPSFYSHGMPARDNVFRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAASTTSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHYKRDADGLCHRLVTPIICETATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTIRNTV
What is the function of this protein?
Non-receptor tyrosine-protein kinase which plays a role in pharynx function by regulating pumping and the orientation of pharyngeal muscle fibers, independently of src-1 and src-2 (PubMed:19210548).  May phosphorylate and thereby negatively regulate src-1 and src-2 activities (PubMed:12527374).
What are the official names of this protein?
Tyrosine-protein kinase csk-1, C-terminal src kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Protein: TLP14_ORYSJ
Sequence: MSFRSIVRDVRDGFGSLSRRGFEVRLVGHRRGRSHSAVHELRDGHAAAAAADVVQSSCWANLPPELLRDVIERLEASEAAWPSRKNVVACAAVCRTWRDMCREIVKNPEFCGKITFPVSLKQPGPRNGAIQCFIKRDKSTQTYNLYLCLSSAVLVESGKFLLSAKRYSRATCTEYTIFMSADNTSRSSNMYIGKLRSNLLGTKFVIYDTQPPCNTANVSQSGKTSRRFYSRKVSPKNPSSTYSIAQVSYELNVLGTRGPRRMNCVMHSIPASSLEAGGTVPCQPDSVLARSLDESFGSISFSKSSIMDRSIRFSSSRYSDISVGGPMVGGQALGDSDESKERPLILRNKAPRWHEQLQCWCLNFKGRVTVASVKNFQLVAATQPAAGAPTPSQPAPPPPPDHDKVILQFGKVAKDMFTMDYRYPLSAFQAFAICLSSFDTKLACE
What are the official names of this protein?
Tubby-like F-box protein 14, OsTLP14, Tubby-like F-box protein 4, OsTLP4.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: YO392_YEAST
Sequence: MKEKSVLEICFSSKYRCLEQAKKSRPVCATFLFSIKISRTDPLTVLIYQVSVLKSPNCDNCKNDSQKDIFFFLSLYLSSIKIPMLILNIFICSYAIFQIPHFTQEFLTGGWIFFKTRRLPVLDVRECAYCVISDSAPRKEILACSDL
What are the official names of this protein?
Putative uncharacterized protein YOR392W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NSP6_ROTHB
Sequence: MNRLQQRQPFLENLLVGVNSTFHQMQKLSINTCCQNLQKILDLLILHRTIHSPAFRLDRMQLRQMQMLACLWIHQRNHDHLATLDTIKWISP
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: THIM1_STRZJ
Sequence: MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPEDLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVADDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVTGEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVYNIAGEMAEKRPNGHLPGTFKVEFINSLYEITDEDVKEFKRVK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 1, 4-methyl-5-beta-hydroxyethylthiazole kinase 1, TH kinase 1, Thz kinase 1.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: MPAL3_LOLPR
Sequence: TKVDLTVEKGSDAKTLVLNIKYTRPGDTLAEVELRQHGSEEWEPMTKKGNLWEVKSAKPLTGPMNFRFLSKGGMKNVFDEVIPTAFTVGKTYTPEYN
What are the official names of this protein?
Pollen allergen Lol p 3, Allergen Lol p III.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1269_SULIY
Sequence: MSKKIINEVIDILEDKKYTYTMIEYPEHNRKSVDIVLNSKEPTLIRVSEDKVTKEEISDLKKIAVSTLTASLVVTNEEEEDIVSVKADNVFAVSPEGFKKVINGEKIFLYRTRGGIFIKIRNYILKHKREEMGYSIGDVAKFLGVSRKAIYDYEKGDSDVSLEVAEKLIDLFGDDIIGDVIWDSIKGKKEVIEEDITEFSPESFKSKLIYKLKENGLNILSLKLTAADLIVKDNENNRYLVTIENKDYNKSMKKFYEAKKLSSYTKSELLIIIRTSKMLKECEDLGYKTYEENDIHSLIDEIKGSNGRQS
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein YG5714_1269.
Protein: CINB_CITBR
Sequence: MSKLQHHSIGEVEPSIAIVGSGPAGCYTAQTLHKQWPSAQIVIFERLPVPYGLLRYGVSPDHQGTKAIARQFDRLFAEASVHFIGNVEVGKHISVEELQDAFDVVVLAAGLGADRPLPSLAGDAVYGAGQVMRWFNSHPDEQSFAPGFGATTTIIGNGNVAMDVVRLLAKHRDSFTGSDLDPQLIEKQPSRIHVVGRSPASAAKFDSMMIRELAEIDDAVFDVDVVDEPGHEDKRIHAKTKALLDLTAARAVPSPRVHVSFHFGWTPESLEPTGDGRTLRLVNTESRLAVKLIETDSVITAVGFGSGLRHEIDRVRFESAASDLDNGLLDTGLYCSGWFRRGPTGGIPANRLDAKMVCTRIIEDVASGAITPKKRGLEELATHLHPDTVDFTGWQRIDAVEASRTEHGRCRTKLPDIATMLDFARNRTHERTTDDTYRKQITDTVGHKEKR
What is the function of this protein?
Involved in the degradation of cineol (eucalyptol).  Catalyzes the reduction of cindoxin (CinC).
What are the official names of this protein?
Cindoxin reductase, CdR, NADPH-dependent flavodoxin/ferredoxin reductase, NADPH-dependent flavodoxin/ferrodoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
Protein: ILVH_ARCFU
Sequence: MKHTIAVLVENKPGVLARVAGLFRRRGFNIESLTVGTTERDDLSRMTIVVEGDDKVVEQVIKQLNKLIETIKVSEITESSVERELCLIRVHAPPEKRGEIVELTNIFRARIVDVSRDSFIIEVTGDEDKVSAFIDLMRQYGIKELARTGKVAMVRGNKK
What are the official names of this protein?
Probable acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: Y2900_BURVG
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAEEGQHRLAVAIDARSSASLDEMPGLIRALSLEHDVRVLFLNASTQSLIQRFSETRRRHPLSGSPSHDANVGLLSSLEEAIERERELVAPLAEFGHQIDTSTLRANVLRTWVKRFIEQKNNDLMVMFESFGFKRGVPLDADLMFDVRALPNPYYDHELRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFREDNRSYLTVAIGCTGGQHRSVFIAETLAARLAHDANVIVRHRDAPVDVDASSRLVADVHRP
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bcep1808_2900.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RS14Z_SULSY
Sequence: MARKCLLVKSFIKKPKYSTRNKSRCPLCGRPRGYIRQFGMCRICFREKALRGEIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CH601_THEFY
Sequence: MAAKLIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPIGLKRGIDAAVARISEELANLSKEVETKEQIASTASISAGDPQIGEYIAEAMDKVGKEGVITVEEGQTFGLELELAEGMRFDKGYISPYFATDLERMETVLEDPYILIANQKISNNNEFLPVIEKVLQAGRPLVVIAEDVEGTALQTLVVNKIRGTFKSVAIKAPGFGDRRKAMLQDIAILTGGQVITEEVGLKLENTELDMLGRARKVVVTKDETTIVDGAGDASAIAGRVNEIRAEIERTDSDYDREKLQERLARLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGILPGGGVALLQASIAAFEKLELEGDEAIGASIVRRAVEEPLKQIAINAGYEGGVVVEKVKSLEPGIGLNAATGEYTDLFKDGVIDPTKVTRSALQNAASIAGLFLTTEAVIAEKPEKPAANNAGGDMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ECO7I
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINISELKTYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1789_STAAC
Sequence: MDWILPIAGIIAAIAFLILCIGIVAVLNSVKKNLDYVAKTLDGVEGQVQGITRETTDLLHKVNRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNSSVDRVTNSITHNISQNEDKISQVVQWSNVAMEIADKWQNRHYRRGSANYKANNVATDANHSYTSRVDK
What are the official names of this protein?
UPF0478 protein SACOL1789.
What is the protein family that this protein belongs to?
Belongs to the UPF0478 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL39L_HUMAN
Sequence: MSSHKTFTIKRFLAKKQKQNRPIPQWIQMKPGSKIRYNSKRRHWRRTKLGL
What is the function of this protein?
Male germ cell-specific component of the ribosome, which is required for the formation of sperm and male fertility.  Replaces the RPL39 paralog in the ribosome of male germ cells.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome.  It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm.
What are the official names of this protein?
60S ribosomal protein L39-like, 60S ribosomal protein L39-2, Large ribosomal subunit protein eL39-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: I23O_YEAST
Sequence: MNNTSITGPQVLHRTKMRPLPVLEKYCISPHHGFLDDRLPLTRLSSKKYMKWEEIVADLPSLLQEDNKVRSVIDGLDVLDLDETILGDVRELRRAYSILGFMAHAYIWASGTPRDVLPECIARPLLETAHILGVPPLATYSSLVLWNFKVTDECKKTETGCLDLENITTINTFTGTVDESWFYLVSVRFEKIGSACLNHGLQILRAIRSGDKGDANVIDGLEGLAATIERLSKALMEMELKCEPNVFYFKIRPFLAGWTNMSHMGLPQGVRYGAEGQYRIFSGGSNAQSSLIQTLDILLGVKHTANAAHSSQGDSKINYLDEMKKYMPREHREFLYHLESVCNIREYVSRNASNRALQEAYGRCISMLKIFRDNHIQIVTKYIILPSNSKQHGSNKPNVLSPIEPNTKASGCLGHKVASSKTIGTGGTRLMPFLKQCRDETVATADIKNEDKN
What is the function of this protein?
Catalyzes the first step in tryptophan catabolism in order to supply de novo nicotinamide adenine dinucleotide (NAD(+)) via the kynurenine pathway.  Plays a role in the cellular response to telomere uncapping.
What are the official names of this protein?
Indoleamine 2,3-dioxygenase, IDO, Biosynthesis of nicotinic acid protein 2.
What is the protein family that this protein belongs to?
Belongs to the indoleamine 2,3-dioxygenase family.
Protein: DNAJ_BRUA2
Sequence: MKIDYYEALGVTRTADDKTLKAAFRKLAMQYHPDRNPDDPEAERKFKEIGEAYETLKDPQKRAAYDRFGHAAFENGGMGGGFGNGFGGAGGFADIFEDIFGEMMGGGRRRSNGGRERGADLRYNMEVTLEEAYAGKTAQIRVPTSITCDECSGSGAKPGSQPTTCTMCSGSGRVRAAQGFFSVERTCPGCNGRGQIIKDPCEKCHGQGRVTQERSLSVNIPTGIEDGTRIRLAGEGEAGLRGGPAGDLYIFLSVKPHEFFQRDGADLYCKVPISMTTAALGGQFEVSTLDGTQTRVKVPEGTQNGKQFRLKGKGMPVLRQSVTGDLYIQIDIETPQNLSKRQRELLEEFEKLSSQENSPKSAGFFSRMKEFFEGIGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_BURPS
Sequence: MSLKKSPFFELRSGSVDTLLFIVKTADLDALRAELVKRFEATPEFFADDVVAIDVRRLADHERVPLDDIRGMLNDVRMRAIGVVAQPEQHAWAASAGLPLLEARDRRAPSSKAADEAPVQQAEPAAPAAGQAALFEQAGPTLADAGAPPESPAPAVAAQSATLVVDRPLRSGQQIYAKGDLVVLGPVSYGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEPELISIAGIYRTTENPLPADVLGKSVQIRLEQEKLMIEPLRLT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: MATRX_PI4HB
Sequence: MAPTQSKVKIHNLAEAHEKVLRAFPIEVEQNSEGNKLLVKQIRIRTLGHADHSNDSICFLNTYGFIKEAVSQTEFMRAGQRPESKNTLTACMLPFGPGPNIGSPQKMLEYAEDIKIHVRKTAGCKEQIVFSLDRTPQVFRGFQFPRDRYVCVPSDKYIKSPGKLVAGPNYCYTITFLSLTFCPSSQKFKVPRPILNFRSTRMRGIHLEIIMKITCSENSPIRKTLITDDPENGPKASVWIHLCNLYKGRNPIKVYDEAYFAEKCKQMLLSVGISDLWGPTIAVHANGKIPKSASLYFNSRGWALHPIADASPTMAKQLWSIGCEIIEVNAILQGSDYSALVDHPDVIYRKIRIDPAKKQYAHSKWNPFKKAISMPDLTGISI
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.