PharMolix/UniProtQA huggingface dataset:
Protein: NQRB_HAEIN
Sequence: MGLKNLFEKMEPAFLPGGKYSKLYPIFESIYTLLYTPGTVTHKNTHVRDALDSKRMMITVFLALFPAIFYGMYNVGNQAIPALNQLGNLDQLIANDWHYALASSLGLDLTANATWGSKMALGAIFFLPIYLVVFTVCTIWELLFSVVRGHEVNEGMFVSTILFALIVPPTLPLWQAALGITFGIIVAKEIFGGVGRNFMNPALAGRAFLFFAYPAQISGDTVWTAADGFSGATALSQWSQGGQGALQHTVTGAPITWMDAFVGNLPGSMGEVSTLAILIGGAVIVFTRIAAWRIIAGVMIGMIATSTLFNLIGSETNPMFSMPWHWHFVLGGFALGMVFMATDPVSASFTNTGKWWYGALIGVMAVLIRTVNPAYPEGMMLAILFANLFAPIFDYIVVQANIKRRRARTNG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit B, Na(+)-NQR subunit B, Na(+)-translocating NQR subunit B, NQR complex subunit B, NQR-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NHAA_RICFE
Sequence: MVVPALIYMFFNYDKPGLIKGWAIPIATDTAFVLGILSFFSRHISLELQAFIIGFTLIDDAFALIILALFYTKTINTPALLISSVIIFILFILNYRQVKQLFYYIIVGLLLWISMVESGIHGTLCGAIIALFIPVNIKGEFNTSFKKLENLTRPFVNYFILPLFVFMNSGILLEYFVFKGTCSNSILALVYGIIFGLFVGKQLGIMLFSYPFVKFKLCNLPSDTSWLKFYSISILGGIGFTLSLFIGSITFESSCPSNSMRAAVIIGSLISALFGVAVLKYCTSKE
What are the official names of this protein?
Putative Na(+)/H(+) antiporter NhaA homolog.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TMCAL_STRP3
Sequence: MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVIDYQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRYTKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP394_ARATH
Sequence: MIKLIRFFRSRRCWVISLQARCFSAPSRTHFDFSGESSDTERALVSALGSCASSNDVTCGRQIHCRVLKSGLDSNGYICNSVLNMYAKCRLLADAESVFRDHAKLDSASFNIMVDGYVRSRRLWDALKLFDVMPERSCVSYTTLIKGYAQNNQWSEAMELFREMRNLGIMLNEVTLATVISACSHLGGIWDCRMLQSLAIKLKLEGRVFVSTNLLHMYCLCLCLKDARKLFDEMPERNLVTWNVMLNGYSKAGLIEQAEELFDQITEKDIVSWGTMIDGCLRKNQLDEALVYYTEMLRCGMKPSEVMMVDLLSASARSVGSSKGLQLHGTIVKRGFDCYDFLQATIIHFYAVSNDIKLALQQFEASVKDHIASRNALIAGFVKNGMVEQAREVFDQTHDKDIFSWNAMISGYAQSLSPQLALHLFREMISSSQVKPDAITMVSVFSAISSLGSLEEGKRAHDYLNFSTIPPNDNLTAAIIDMYAKCGSIETALNIFHQTKNISSSTISPWNAIICGSATHGHAKLALDLYSDLQSLPIKPNSITFVGVLSACCHAGLVELGKTYFESMKSDHGIEPDIKHYGCMVDLLGKAGRLEEAKEMIKKMPVKADVMIWGMLLSASRTHGNVEIAELAATELAAIDPSHGGCKVMLSNVYADAGRWEDVALVREEMRTRDVEWSRAFSGVV
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g19020, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECX_AMYMU
Sequence: MPPAELPPEERYKKAKEICFDLLAVRARTQEELRQALRRKGFDEETSETLLGKLDRAGLVNDAEFAELWVKSRHTTQGLSRTALMAELRRKGVDDEVAAQAAGEVDRESEEQMARELVRKRLGSLGNVDEQTALRRLLGFLARKGYPQGLAYTVIKEELREYGAESTLLDDAVID
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOT8_MOUSE
Sequence: MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI
What is the function of this protein?
Specific thyroid hormone transmembrane transporter, that mediates both uptake and efflux of thyroid hormones across the cell membrane independently of pH or a Na(+) gradient (PubMed:31436139).  Major substrates are the iodothyronines T3 and T4 and to a lesser extent rT3 and 3,3-diiodothyronine (3,3'-T2).  Acts as an important mediator of thyroid hormone transport, especially T3, through the blood-brain barrier (PubMed:19147674).
What are the official names of this protein?
Monocarboxylate transporter 8, MCT 8, Solute carrier family 16 member 2, X-linked PEST-containing transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SRP19_NATPD
Sequence: MVENVIWPAYLDANCTRNEGRRVAEDLAVEEPTVDEIASAVQQVGYDAVIERSKTYPREYEPRGRVVVKGADDASKSDLLEAVAAYVTAIRE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBPL_MOUSE
Sequence: METSPISPMNEKNTAQPQQREENAQQILNTAIPFRQRSPGLLPEALKVGVRPDPANQIVETQEIEHPVAGFEGDSDQFQVSTNEMAEHLQASDLWYCPDGSFVKKIIVPGHGLDKPKLGSKCQVLALGFPFGSGMPEGWTELTIGIGQWREKMWGELMEKCLESMRQGEEAKIHLPGSSAPLAKLRLDSFTNGRDSWEMEAMEKEALAKEEHRRGTELFRAGNPQGAARCYGRALRLLLTLPPPGPPERTTLYANLAACQLLLGHPQLAAQSCDRVLEREPGHLKALYRRGVARAALGDLEKATADFKKVLAVDPKNRAAKEELGKVVIQGRKQDAGLARGLRKMFS
What is the function of this protein?
May be involved in response to X-ray.  Regulates p21 protein stability by binding to Hsp90 and p21.
What are the official names of this protein?
FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39.
Protein: NDK_RALPJ
Sequence: MALERTLSIIKPDAVAKNVIGQIYARFEGAGLKIVAAKMIHLSRAEAEQFYAVHKERPFFKDLVDFMISGPVMVQALEGENAIAKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEVAFFFPGLNIYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y596_MYCPN
Sequence: MVVIAALLGSLAVLAFLFYLWYLTIFIIVHKNQQYLEQTKALYNKLKLSNFNSVIVPFQLLRSEKKALEQPVKLLKSFQESFNSEINSALEQLLVFSEPKALYNCFWFNRNIKLLRKNLQGLHDKQQRYVKLTKNAIAYFDSSYDTLVFYRQAFCLLVSFINDFLVHKYDSLFYLNIINRISLLFKDVELHIKNKDVKQQNQALNKLHNNLAQTIITASRQYFFDVKVGYLNYHFQILSQKVTQLRSMKNKAINSQEVAKFQELITNIGATLAECSQALGNINLALCEQRINQAKEQIDVLSNAVSVKEKAISLVVSNVDSFLKSINHYQQQNALLQTLMKEIELMFQNNLDTVNIINQINEHSLLIAQKTQLLNQENALTEFIDYEKLFRLMSEAMKLLDGLKNLLNELFALSANKFDDYRFFVYTLDDFRFKFFQIENLIANEELIISEKTLKIISQAKHQFDDIFTQAKNDYEGAFSYLNEKVRFFQNQLTHVIVDVVGLMNLRSMCKHTFIFANKYRQESPQINESLETLTQFYQQQNYSETLSGLISLLGKIKSSAKQHHLDLN
What are the official names of this protein?
Uncharacterized protein MG397 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL27_MYCTA
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRYGGQVVKAGEILVRQRGTKFHPGVNVGRGGDDTLFAKTAGAVEFGIKRGRKTVSIVGSTTA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CAG_GEOKA
Sequence: MIYPYKGKTPQIAASAFIADYVTITGDVVIGEETSIWFNTVIRGDVAPTVIGNRVNIQDNSILHQSPNNPLIIEDGVTVGHQVILHSAIVRKNALIGMGSIILDRAEIGEGAFIGAGSLVPPGKKIPPNTLALGRPAKVVRELTEDDIREMERIRREYVEKGQYYKALQQQRTSCADKKELP
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase, Gamma-carbonic anhydrase, Cag.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
Protein: RSSA3_SCHJY
Sequence: MAESVAHPSVLNATEEDIKQLLAASCHIGSKNLEIRMENYVWKRRADGVNIINIGKTWEKIVLAARIIATVENPADVCVVSSRPYGHRAVLKFAAHTGATAIAGRFTPGNFTNYITRTFREPRLIIATDPRADAQAIKEASYVNIPVIALCDTDSPLAHVDVAIPTNNKGYKSIGLVWWLLAREVLRLRGALTRTGAWDVMVDMYFYRDPEEIEREEEAKAAAEAAAEAATTAEAAAEFEAVAAGAVDADVLAAATAGQVGEGAWDEAATGDWSTVGASTSDWTATAAQ
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0-C.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCC4_YEAST
Sequence: MENLGDKLSISQVYHLAQEYRDHAYSIANKIGSEEGLKQYYGLMNMSIQMFQLLKTKCTLSVLEDSKVTFEMVELLIQETYNFDLAELYISSLKERLQTHQSDTDLVEEIMRCEFLLLHDLPLMRDSKFHYKIALRNCNELVQYMVNLQDELYQNWASVFQYVGVMLCIKLKQHRRVKTSFHGLLSQCREKSQWKWFLNLCYVNYLLNERFPIPEDALQELRSTELHTVGPELYAWKLALEMVIQLCKDGNITDHLNEFKNFFDTNKQSLVTNEGKGCVIKIMPRIALKVELPMIFHYKELKNILLLLQSVSYIVNCYDEKGNFSRKFLPKVYSTTQKLIKNIAAGGVSMNELDSRIQTYKSILEFCEFYKVWEQTLLKGAVVTTESPKLGPSPGYVRLLQAMKVQFEGGGAVEEYTRLAQSGGTSSEVKMISLLNCYTVQAARVSRCSGDKQGELVEQCNKVWLQVEKLLQETDLQFNPIWECTVTILWLFSHFEPFSWNPLPCSDKQRAEYVSKLREFYSSNKFVAGEAVADNRFKLKKALLLQILVNYLGGRMLEHDLGEIYAISAKCFDMCRQQGGMRKVQYVIGIWHLMNCTVAMRGKDVALTNAKLEALVKQITSVKQ
What is the function of this protein?
Involved in sister chromatid cohesion (PubMed:10882066).  Forms a complex with SCC2, which is required for the association of the cohesin complex with chromosomes (PubMed:10882066, PubMed:26038942).  Binds to the nucleosome-free promoter regions of ribosomal protein genes and tRNA genes (PubMed:25173104).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Sister chromatid cohesion protein 4.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin.
Protein: LIS1_YEAS7
Sequence: MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLINVESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNYTNSSKKNYLVIVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSIDVLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTLKGHLSWVRDISIRGQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNCLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: EXOK_RHIME
Sequence: MTIDRYRRFARLAFIATLPLAGLATAAAAQEGANGKSFKDDFDTLDTRVWFVSDGWNNGGHQNCTWSKKQVKTVDGILELTFEEKKVKERNFACGEIQTRKRFGYGTYEARIKAADGSGLNSAFFTYIGPADKKPHDEIDFEVLGKNTAKVQINQYVSAKGGNEFLADVPGGANQGFNDYAFVWEKNRIRYYVNGELVHEVTDPAKIPVNAQKIFFSLWGTDTLTDWMGTFSYKEPTKLQVDRVAFTAAGDECQFAESVACQLERAQSE
What is the function of this protein?
Cleaves high molecular weight succinoglycan to yield LMW succinoglycan.  Dynamically regulates the molecular weight distribution of succinoglycan by cleaving nascent succinoglycan only during a limited period after its synthesis, perhaps before it undergoes a time-dependent change in its conformation or aggregation state.
What are the official names of this protein?
Endo-1,3-1,4-beta-glycanase ExoK, Succinoglycan biosynthesis protein ExoK.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPGH_XYLFT
Sequence: MQALMEMQIGASEVVQVLDTGCAVLPPESPLPMPEQSLRKGRLHVPRQRTAPLGIGLRRFYLIGGTMSMSLIATWVMLAVMWPGGINVLEGCLLVLFMFLFAWVTMSFASALAGFFCMVFGGGRKLGIDPQMPLPDLHTYTALLVPTYQEDPCRLLAGLQAIYESLSETGQLEHFEFFVLSDSRREEFGLAEEREYAALCERLGAHGRIFYRRRADNTGRKAGNIADWVRRFGGAYQQMLILDADSVMTGDTVVRLVAAMESNPDVGLIQSLPVVVGGRTLFARMQQFGACVYGPIIAYGVAWWHGAESNYWGHNAVIRTKAFADHAGLPALPGRKPFGGHVLSHDFVEAALIRRGGWATHMVPYLQGSYEEGPPTLTDLLIRDRRWCQGNLQHAKIVTAAGLHWISRMHMLIGIGHYFTAPMWGLLMLVGIAIPLVGDGIDLTAGMHFSPAHYWHGRTDGDVLWIFTFTMFVLLAPKLLAYFALLFKPYERRACGGALRVLLSILLESILAALMAPIVMYLQSRGVFEVLAGKDSGWDAQQRDDGKLSWSVLLRSYGGLSVLGVLIGALAYTVSPPLAMWMSPVVLGMAFSVPVVALTSHRLVGAVLRRWGIFLIPEETAPSKVLIRVAELRRARQP
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LACB_STAAB
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETRNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RS5_PSYWF
Sequence: MAKVEQNDGLVEKLVSVDRVSKVVKGGRIFSFTALTVVGDGNGRVGFGRGKAREVPAAIQKALEAAKRNMITVDLDGATLQHPIIARHGASKVYMQPANEGTGVIAGGAVRAVLESAGVENVLTKCYGSTNPTNVVRATFNGLRDMSSPEKAAAKRGKSVDEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ACPS_SALDC
Sequence: MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_BACFR
Sequence: MKNLERLFAEKLLKIKAIKLQPANPFTWASGWKSPFYCDNRKTLSYPSLRSFVKFEITRLVLERFGQVDAIAGVATGAIPQGALVADALNLPFVYVRSTPKDHGLENLIEGELRPGMKVVVVEDLISTGGSSLKAVEAIRRDGCEVIGMVAAYTYGFPVAEQAFKDAKVPLVTLTNYEAVLDVALRTGYIEEEDIATLNEWRKDPAHWETGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: POLG_FCVUR
Sequence: MSQTLSFVLKTHSVRKDFVHSVKRTLQRRRDLQYLYNKLSRPIRAEACPSCASYDVCPNCTSGSIPDDGSSKGQIPSWEDVTKTSTYSLLLSEDTSDELHPDDLVNVAAHIRKALSTQSHPANVDMCKEQLTSLLVMAEAMLPQRSRSTLPLHQKYVAARLEWREKFFSKPLDFLLEKIGTSRDILQITAVWKIIIEKACYCKSYGEHWFEAAKQKLREIKSYEHNTLKPLIGAFIDGLRLMTIDNPNPMGFLPKLIGLIKPLNLAMIIDNHENTLSGWVITLTAIMELYNITECTIDVITSIITGFYDKIGKATKFYSQIKALFTGFRSEDVANSFWYMAAAILCYLITGLIPNNGRLSKIKACLAGATTLVSGIVATQKLAAMFATWNSESIVNELSARTVAISELNNPTTTSDTDSVERLLELAKILHEEIKIHTLNPIMQSYNPILRNLMSTLDGVITSCNKRKAIAKKRPVPVCYILTGPPGCGKTTAALALAKKLSDQEPSVINLDVDHHDTYTGNEVCIVDEFDSSDKVDYANFVIGMVNSAPMVLNCDMLENKGKLFTSKYIIMTSNSETPVKPSSRRAGAFYRRVTIIDVANPLAESHKRARPGTSVPRSCYKKNFSHLSLAKRGAECWCKEYVLDPKGLQHQSIKAPPPTFLNIDSLAQTMKQDFTLKNMAFEAENGHSEHRYGFVCQQGEVETVRRLLNAVRTRLNATFTVCVGSEASSSIGCTAHVLTPDEPFNGKKYVVSRCNEASLSALEGNCVQSALGVCMSTKDLTHLCHFIRGKIVNDSVRLDELPANQHVVTVNSVFDLAWALRRHLTLAGQFQAIRAAYDVLTAPDKVPAMLRHWMDETSFSDEHVVTQFVTPGGIVILESCGGARIWALGHNVIRAGGVTATPTGGCIRFMGLSAQTMPWSEIFRELFSLLGRIWSSIKVSTLVLTALGMYASRFRPKSEAKGKTKSKVGPYRGRGVALTDDEYDEWREHNATRKLDLSVEDFLMLRHRAALGADDADAVKFRSWWNSRSRLADDYEDVTVIGKGGVKHEKIRTNTLRAVDRGYDVSFAEESGPGTKFHKNAIGSVTDVCGEHKGYCVHMGHGVYATVAHVAKGDSFFLGERIFDLKTNGEFCCFRSTKILPSAAPFFPGKPTRDPWGSPVATEWKPKPYTTTSGKIVGCFATTSTETHPGDCGLPYIDDNGRVTGLHTGSGGPKTPSAKLVVPYVHIDMKTKSVTAQKYDVTKPDISYKGLICKQLDEIRIIPKGTRLHVSPAHTEDFEECSHQPASLGSGDPRCPKSLTAIVVDSLKPYCDKVEGPPHDILHRVQKMLIDHLSGFVPVNISSETSMLSAFHKLNHDTSCGPYLGGRKKDHMTNGEPDKPLLDLLSAKWKLATQGIALPHEYTIGLKDELRPVEKVAEGKRRMIWGCDVGVATVCAAAFKGVSDAITANHQYGPVQVGINMDSPSVEALHQRIKSAAKVYAVDYSKWDSTQSPRVSAASIDILRYFSDRSPIVDSAANTLKSPPIAIFNGVAVKVSSGLPSGMPLTSVINSLNHCLYVGCAILQSLEARGVPVTWNLFSTFDMMTYGDDGVYMFPMMFASVSDQIFANLSAYGLKPTRVDKSVGSIEPIDPESVVFLKRTITRTPQGIRGLLDRSSIIRQFYYIKGENSDDWKTPPKSIDPTSRGQQLWNACLYASQHGVEFYNKIYKLAQKAVEYEELHLEPPTYHSALEHYNNQFNGVEARSDQIDSSGMTALHCDVFEV
What is the function of this protein?
Protease-polymerase p76 processes the polyprotein: Pro-Pol is first released by autocleavage, then all other proteins are cleaved.  Cleaves host translation initiation factor eIF4G1, eIF4G2 and PABP1 thereby inducing a shutdown of host protein synthesis.  This shutdown may not prevent viral mRNA from being translated since viral Vpg replaces the cap.  May cleave host polyadenylate-binding protein thereby inhibiting cellular translation.  It is also an RNA-directed RNA polymerase which replicates genomic and antigenomic viral RNA by recognizing specific signals.  Transcribes also a subgenomic mRNA by initiating RNA synthesis internally on antigenomic RNA.  This sgRNA codes for structural proteins.  Catalyzes the covalent attachment VPg with viral RNAs.
What are the official names of this protein?
Genome polyprotein.
Protein: TXNG2_PANTR
Sequence: MEEAGLCGLRRKADMLCNSESHDILQHQDSNCSATSNKHLLEDEEGSDFITKNRSWVSPVHCTQESRKELPEQEVAPPSGQQALQCNRNKEKVLGKEVLLLMQALNTLLTPEEKLAAVCKKYADLGNSPLL
What are the official names of this protein?
Putative gamma-taxilin 2.
What is the protein family that this protein belongs to?
Belongs to the taxilin family.
Protein: MVP_TOMS1
Sequence: MALVVKGKVNINEFIDLSKSEKLLPSMFTPVKSVMVSKVDKIMVHENESLSEVNLLKGVKLIEGGYVCLVGLVVSGEWNLPDNCRGGVSVCLVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYGITTKDAEKNIWQVLVNIKNVKMSAGYCPLSLEFVSVCIVYKNNTKLGLREKVTSVNDGGPMELSEEVVDEFMENVPMSVRLAKFRTKSSKRGPKNNNNLGKGRSGGRPKPKSFDEVEKEFDNLIEDEAETSVADSDSY
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.  Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma. Note=Binds to the host cytoskeleton before being transported to the host plasmodesmata. Observed in virus replication complexes (VRCs) of tobamovirus infected host cells (By similarity). In resistant plants, targeted to the host plasma membrane via the interaction with host resistance (R) protein TM-2 (e.g. tomato ToMV resistance protein TM-2(2), AC Q71BG9) (By similarity).
Protein: CPEB1_HUMAN
Sequence: MALSLEEEAGRIKDCWDNQEAPALSTCSNANIFRRINAILDNSLDFSRVCTTPINRGIHDHLPDFQDSEETVTSRMLFPTSAQESSRGLPDANDLCLGLQSLSLTGWDRPWSTQDSDSSAQSSTHSVLSMLHNPLGNVLGKPPLSFLPLDPLGSDLVDKFPAPSVRGSRLDTRPILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSLSGGGPRDPLKMGVGSRMDQEQAALAAVTPSPTSASKRWPGASVWPSWDLLEAPKDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGNMPKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTTKFTKKVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKNRDSS
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons.  Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR.  RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967).  In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity).  Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity).  Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity).  Induces the assembly of stress granules in the absence of stress.  Required for cell cycle progression, specifically for prophase entry (PubMed:26398195).
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 1, CPE-BP1, CPE-binding protein 1, h-CPEB, hCPEB-1.
What is the protein family that this protein belongs to?
Belongs to the RRM CPEB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Cytoplasmic granule. Synapse. Membrane. Postsynaptic density. Cell projection, dendrite. Note=Continuously shuttling between nucleus and cytoplasm (PubMed:18923137). Also found in stress granules. Recruited to stress granules (SGs) upon arsenite treatment. In dendrites (By similarity). Localizes in synaptosomes at dendritic synapses of neurons (By similarity). Strongly enriched in postsynaptic density (PSD) fractions (By similarity). Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin (By similarity). Membrane-associated (By similarity). Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity).