PharMolix/UniProtQA huggingface dataset:
Protein: RS11_LEVBA
Sequence: MATRKTSRKRRVKKNIEAGVAHIHATFNNTLVMITDVQGNAIAWSSAGALGFKGSRKSTPFAAQMAAEAAAKASQEHGIKSVEVAVKGPGSGRESAIRAIQAAGIEITAIRDVTPVPHNGTRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ACCD_NICSY
Sequence: MERWWFNSMLFKKEFERRCGLNKSMGSLGPIENTNEDPNRKVKNIHSWRNRDNSSCSNVDYLFGVKDIRNFISDDTFLVSDRNGDSYSIYFDIENHIFEIDNDHSFLSELESSFYSYRNSNYRNNGFRGEDPYYNSYMYDTQYSWNNHINSCIDSYLQSQICIDTSIISGSENYGDSYIYRAVCGGESRNSSENEGSSRRTRTKGSDLTIRESSNDLEVTQKYRHLWVQCENCYGLNYKKFLKSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYAANQILPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNLLKSVLSELFKLHAFFPLNQKSSKIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: KTN81_ARATH
Sequence: MAKRGYKLQEFVAHSGNVNCLSIGKKTSRLLLTGGDDYKVNLWSIGKTTSPMSLCGHTSPVDSVAFNSEEVLVLAGASSGVIKLWDLEESKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDTNLRVWDTRKKGCIQTYKGHTRGISTIEFSPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKCHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGTTRPEATGVRAIAFHPDGQTLFCGLDDGLKVYSWEPVICRDGVDMGWSTLGDFCINEGKFIGCSYYRNSVGIWVSDISELEPYGAVSEDKNECMVKRFSVLNDQSERMGSGPRGSVSPDYETREIKNIYVDCGNLNVAQNPGSLKATLPLESGKVATMVSEKQNAAYFGPAGDKYSSTSRDSDSGEESSYSERESIPFSRTKSGMLLRPAHVRKTLAKFEESKQSAVVQSATRKKSGLAVEEEPQTQNAFLSEQNASKPFDAEDSIIKGITNKFEKALSSEPPTDEANRMFLKPPRIHRSSNSKYNDTRRAMSADPATFGKGGMENSGDVEDIPSKTERVLSREKPGDEQKNTEYPSGSRELNPVKIVEGVNVVSGRTRSLVEKFERGEKTTHTEGASTTIEQNNNAVQEDPRKTSRQTGETPVISTRRARSTPARVMPIVLNRDSNVTSDEPPLTQPARTSSFPVMPVILNQASNVTYDEPSVALTQESRTSHARILPVTFNQATNITSEEASVTLRRQRRNSAARVRPVLLSQATSHECPVTSVRPLRTSPARVMPTKLNQSVNMTSDTSHIASMHRVSPTQMLATPTVIDQVADMTLDETHATQIQPACDNMPQKEEPNISDREDDSDITENLMLTHNEFLSTLQSRLTKLQIVRHFWERSDVKGAIGALRKLTDQSVQADVISILTEKIEILTLDMFSQLVPVLTSLLGSRTERPVNVSLDMLLKLVAVFGTVIRSTVSAPRIVGVDLHANERLEICQICSAGLHKIQRILPVLARRGGLITRKAQELNLVLQEP
What is the function of this protein?
May participate in a complex which severs microtubules in an ATP-dependent manner (By similarity).  Microtubule severing may promote rapid reorganization of cellular microtubule arrays (By similarity).  Confers precision to microtubule (MT) severing by specific targeting of KTN1 to MT cleavage sites such as crossover or branching nucleation sites (PubMed:28978669).  Together with other KTN80s, regulates cell elongation by modulating MT organization (PubMed:28978669).
What are the official names of this protein?
Katanin p80 WD40 repeat-containing subunit B1 homolog KTN80.1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat KATNB1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present in dynamic discrete particles specifically localized to microtubule (MT) crossovers and branching nucleation sites.
Protein: STIM1_MOUSE
Sequence: MDVCARLALWLLWGLLLHQGQSLSHSHSEKNTGASSGATSEESTEAEFCRIDKPLCHSEDEKLSFEAVRNIHKLMDDDANGDVDVEESDEFLREDLNYHDPTVKHSTFHGEDKLISVEDLWKAWKSSEVYNWTVDEVIQWLITYVELPQYEETFRKLQLTGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKDFMLVVSIVIGVGGCWFAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAERQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQLGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMGRAADEALNAMPSNGSHRLIEGVHPGSLVEKLPDSPALAKKTFMALNHGLDKAHSLMELNPSVPPGGSPLLDSSHSLSPSSPDPDTPSPVGDNRALQGSRNTRIPHLAGKKAMAEEDNGSIGEETDSSPGRKKFPLKIFKKPLKK
What is the function of this protein?
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores.  Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain.  Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1.  Involved in enamel formation.  Activated following interaction with STIMATE, leading to promote STIM1 conformational switch.
What are the official names of this protein?
Stromal interaction molecule 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Sarcoplasmic reticulum. Cytoplasm, cytoskeleton. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular Ca(2+) and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane. Associated with the microtubule network at the growing distal tip of microtubules. Colocalizes with ORAI1 at the cell membrane. Colocalizes preferentially with CASQ1 at endoplasmic reticulum in response to a depletion of intracellular calcium (By similarity).
Protein: AMPA_CLAM3
Sequence: MTLPLLSVSSDRAVDVEADALVVAVSSEKEGLRVHAPEGLEFDADGLSDIGVTGGRDEVVRIAGTGTAARTIAFVGVGSGPVDAVALRYAVGSATRQLRGVAHVAVAVPVSSLVDLTAVLEGAALGTYSFDAYRRDSLAGQKPRATAVTVLAQGDSWTADDADEAVAHATAVAGAVAGTKDLVNTPPLDLYPATFVDAVHERTAGLPVDVRVWDEVALAADGFGGILGVGQGSTRPPRLVKVAYSPAGATRHLALVGKGITYDTGGISLKPAVPMIGMKYDMTGAATILEVVVAAARLELPVRLTAWLCIAENMPSGSAIRPDDVLRMRGGTTVEVLNTDAEGRLVMADGIVAASEEHPDAIVDIATLTGAQVVALGERYSAVMGEDALVARLLDAAREQGESMWGMPLPEEMRALLNSDIADIANVKPGNPAGGMLVAGVFLKEFVGRTGDEDDAPRIPWAHVDIAGPSHNKGGGHGFTGKGPTGVAVRTLLALAAGFSRA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUS5_BOVIN
Sequence: MPFFDVQKRLGVDLDRWMTIQSAEQPHKIPSRCHAFEKEWIECAHGIGSIRAEKECKIEFEDFRECLLRQKTMKRLHAIRRQREKLIKEGKYTPPPHHSGQEEPRS
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5, Complex I-15 kDa, CI-15 kDa, NADH-ubiquinone oxidoreductase 15 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: AROC_HAEIE
Sequence: MAGNTIGQLFRVTTFGESHGIALGCIVDGVPPNLELSEKDIQPDLDRRKPGTSRYTTPRREDDEVQILSGVFEGKTTGTSIGMIIKNGDQRSQDYGDIKDRFRPGHADFTYQQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLREHFGIEVRGFLSQIGNIKIAPQKVGQIDWEKVNSNPFFCPDESAVEKFDELIRELKKEGDSIGAKLTVIAENVPVGLGEPVFDRLDADLAHALMGINAVKGVEIGDGFAVVKQRGSEHRDEMTPNGFESNHAGGILGGISSGQPIIATIALKPTSSITIPGRSINLNGKPVEVVTKGRHDPCVGIRAVPIAEAMVAIVLLDHLLRFKAQCK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GBG_CAEBR
Sequence: MENIKTTTEQLRTEANIQRKKVSEVAKDLVEFCEKNKATDMLVSGPLDAHNPFQEKKSCSVL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: UPPP_BUCAI
Sequence: MLDLHQVIVSIIIGVIEGITEFLPISSTGHMIIASHWLKIDNENTKILEIFIEFGSALSILYFFHKKILRILKFNINVKKTNTKNLHILLAILPTIFFGLLFYKKIKLLFNTYNVMYALILGGIFLLISEIFKPKKYKTCSINDISLLQSAIIGFFQIFCLYPGFSRSGATIGTAILLGIKRSVAIEFSFIISIPLIMGASFYDFINNMHNFKILDLPIFFIGFMISFIVSILCIKKLLKIINRTSLIFFGIYRFIISGLIYFIN
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EF2_PYRNV
Sequence: MSSAVRVVEKQLDEILAIARNPAQIRNAGTLAHVDHGKTTTSDSLLMGAGLLSPKVAGKALAMDYVPIEQLRQMTVKAANISLYFEYGGKPYLINFVDTPGHVDFTGHVTRSLRVMDGGLVVVDAVEGVMTQTETVVRQALEEYVRPVLFINKIDRLIKELRLSPQEIQQRILTIVKDFNALIDMFAPPEFKDKWKVDPGKGQMAMGSALHKWGITIPMAQKAGIKFSNIVDAYEKGYVDQLAQEFPLYKTLLTMIIEHVPPPNVAQKYRIPRLWRGDLNSEIGKALLEADPNGPTVIAVSKVNKDPHAGLIATGRVFSGTIREGDEIYIIGRKMKKKVLQTYIYMGPSRIIVPYMPAGNIVALMGVDEARAGDTLVDPRLSEIPPFEKMRYISEPVVTVAIEPKNPAELARLVEALKDLVIEDPTLDLKIDQETGQILLSGVGTLHLEIATWLLKERTKTEFTVSPPLIRFRETVRERSQVWEGKSPNKHNRLYFYVEPLDETTIELIATREITEDQDPRERAKILREKAGWDADEARGIWAIDDRFFNLIVDRTSGIQYLREIRDYIVQGFRWATEAGPLAQEPMRGLKVVLTDAVVHEDPAHRGPAQIMPATKNAIFAAVLSARPTILEPLMKLDIKVAPDYIGAVTSVLNKHRGKILDMTQQEYMAYLRAELPVLESFTISDELRAAAAGKIFWSMQFSRWAPMPESILADMVKQLRKKKGLKEEIPKPTDFVEAF
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_GRAFK
Sequence: MGNNKSGSEDNHKVWEVNESSKCPFMGGALNKTAGKGTSNRDWWPNQLNLNILRQNSSLINPMDDGFNYAEAFKSLDLNAVKQDIYDLMTNSQDWWPADYGHYGPFFIRMAWHSAGTYRIGDGRGGAGSGQQRFAPLNSWPDNANLDKARLLLWPVKKKYGKNLSWADLLVLAGNCAHESMGLKMFGFAGGREDVWEPAQDVYWGAETEWLNNDERYAGEELENPLGAAHMGLIYVNPEGHNGNPDPVEAASYIRETFGRMAMNDYETVALIAGGHTFGKTHGAADAEEYVEAEPAAAGIESQGLGWKNTFGTGNGADTITSGIEGAWTDTPTKWSNKYFDNLFKYDWECIKGPGGAYQWQPKDNAGAGTVPDAHDPDKKHAPFMLTTDLSLKMDPEYEKISRHFYENPDEFADAYSRAWFKLTHRDMGPIERYLGPEVPKEELLWQDPIPKVDHEIINDSDIASLKNKILNTGLSVQELVTTAWGSASTFRGSDKRGGANGGRIRLAPQNGWEVNNPKQLGKVIDTLEKIQQDFNESQSGSKKVSIADLIVLAGCVGVEKAAKTAGHELKVPFSPGRADASQEQTDVEAFEPLEPNADGFRNYFRNRDHVSASAEELLVDRAQLLTLTVPQMTVLLGGMRAMGANYDGSKKGVFTDRPGQLTNDFFKNILEMGLTWKSSSDSETEFDGSDRKTGDVKWTGSRADLIFGSNSELRAIAEVYGTDDVEAKFVKDFVKAWDKVMNLDRYDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: F16PA_ALISL
Sequence: MSEIRTLGEFIVAKQHDFPHASGELSSLIGSIKLAAKIVNREINKAGLVDITGASGDENIQGEQQQKLDIYANDKFKAALENRDQVCGVASEEEDEAVAFNKELNKNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRISPIGSPATEEDFLQPGNKQVAAGYIIYGSSTMLVYTTGNGVHGFTYDPSLGVFCLSHEDMKIPQDGNIYSINEGNYIRFPEGVKQYLKYCQEIKPAENRPYTSRYIGSLVADFHRNLLKGGIYLYPSTQAYPNGKLRLLYECNPMAMLIEEAGGKATSGEERILDITPTELHQRVPFFVGSINMVDKVQNFLDEWQD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_CITBB
Sequence: MANLKSIKKRIVSVKNTRQITKAMKMVSAAKLRRAQENVVAARPYAGKLAEVLERLAKTQESDASPLMVKRDTRRALLVVVTSDRGLCGGFNANLSKAAERFINERKGDFSELSLMTIGRKGYEFLRNRHTVRKHHGNIFSTLSYHTAALIAAELVEGYLAEEYDEVYVIYNAFKSVMTQDITLEQLLPVTAKTADTDEVGTEYIYEPSKAALLDELLPKHIEVQVFKSLLESVASEHGARMTAMDSASKNATEMIGKLTLIYNRARQAAITTELMEIISGSESIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLUC_BUCAP
Sequence: MKYKTTSVSIIYINEDMINQRIDNFLQKKLKNVPRSMIYRIIRTGKIRINKKRIKPDYKLKIGDKLRIPPIKILCEKKSSLLTTEYKKNLLNNILYEDNYLLIINKPSGIAVHGGSGINLGVIEYFRKIRPLEKFLELVHRIDRDTSGVLMLAKKRRSLLSLHKQIREKKVQKKYIALVHGLWPLSLRKVSEPLLKTHLKNKQRKILINKEGKPAETYFKIKKQYLFTTLVSITPKTGRTHQIRVHTLHAGHPILFDKRYGKRDLDCNIKNKTKINRLLLHATSINFIHPETGKKMHIVAPLDVYFKNYLNTLI
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase C, 23S rRNA pseudouridine(955/2504/2580) synthase, rRNA pseudouridylate synthase C, rRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: HSLV_SHIDS
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_LACDB
Sequence: MTSRYKLTLSYDGHDFHGFQSQPGQRTIQGTVEEILKQMTKGQEVRVFGSGRTDAGVHSVGQVIHFDYPGREIPAANMIKALNSQLPMDMVFTDCEIVDKDFHSRFSVKGKWYRYRVSLDGFVNPFKRFYTGHYPYPVDVEKMQEAAKDLLGRHDFTSFAASGGQIEDKVRDMYYVNVALDEENNEVIMDFIATGFLYNMVRILVATLLEIGNGRRPVHDLKRVIAAKNRLEVQQTAQACGLYLYHVFYEEVPRKYRLDLDL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GNAI2_RAT
Sequence: MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPQRADDARQLFALSCAAEEQGMLPEDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITQSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.  May play a role in cell division.
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha-2, Adenylate cyclase-inhibiting G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane; Lipid-anchor. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody (By similarity).
Protein: PLCX3_DANRE
Sequence: MASSQGKSELRYADWMSSLPDTLHGIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTSQLEAGIRFFDLRISTKPRDPDNELYFAHGLFSATVREGLEQISTFLASHAREVVFLDFNHFYGVQNLHHEKLVQMLRTVFGDRLCPVVFAQEVSLKYLWEKEYQVLVFYHNPMALEVPFLWPGQMMPAPWANTTDPEKLILFLQASVKDRRRKGTFFVSQVVLTPKASTVMKGVTSGLRETITERALPSMMQWIRSQRPGESGVNIITADFVELGEFISAVITLNYYLDDEEENAT
What are the official names of this protein?
PI-PLC X domain-containing protein 3.
Protein: Y4665_ALKMQ
Sequence: MKRLILETLKAEVVPAIGCTEPIAVALACAKAREIAGVSIDEVDHVDVIVSPNVYKNGLAVGVPHTEHIGLAIAAALGLTGGKCHQGLQVLEGMKKTEQDIAVSLMDQGLISLDIKDTNEKVYIEVILSIQGWKAKVIIKERHNQFVYLEKQGHVLLDSKTVPGVIASHQNPLYHMEIKEIIAIIEQIPHEELAFMMDGVEMNKKMAMTGLQPGVGMGVGYTYYDNMKKGILSDDIMNQAMMLTAAASDARMSGSILPVMSSNGSGNNGITAILPIVAYGMKFQVEDEKMAKALAISHLMNSYIKHYIGRLSALCGCGVAAGTGASVAIAWLMGAKEQQIDGVIKNMLANVSGMICDGAKVGCALKLATSAQVAIQSALLAMDHHIVPTGNGIVAETAEGTIENLRILSEEGMQLTDHAILSVMMKFQRARESHIKDDVLTHEKYVV
What are the official names of this protein?
UPF0597 protein Amet_4665.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: PETG_AETCO
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COLD_ECOCB
Sequence: MINYPLASSTWDDLEYKAIQSVLDSKMFTMGEYVKQYETQFAKTFGSKYAVMVSSGSTANLLMIAALFFTKKPRLKKGDEIIVPAVSWSTTYYPLQQYGLRVKFVDIDINTLNIDIESLKEAVTDSTKAILTVNLLGNPNNFDEINKIIGGRDIILLEDNCESMGATFNNKCAGTFGLMGTFSSFYSHHIATMEGGCIVTDDEEIYHILLCIRAHGWTRNLPKKNKVTGVKSDDQFEESFKFVLPGYNVRPLEMSGAIGIEQLKKLPRFISVRRKNAEYFLDKFKDHPYLDVQQETGESSWFGFSFIIKKDSGVIRKQLVENLNSAGIECRPIVTGNFLKNTDVLKYFDYTVHNNVDNAEYLDKNGLFVGNHQIELFDEIDYLREVLK
What is the function of this protein?
Involved in the biosynthesis of L-colitose, a 3,6-dideoxyhexose present in the O-antigen region of lipopolysaccharides (LPS), where it serves as an antigenic determinant and is vital for bacterial defense and survival.  Catalyzes the removal of the C3'-hydroxyl group from GDP-4-keto-6-deoxy-D-mannose via a combined transamination-deoxygenation reaction.  The catalysis is initiated by a transamination step in which pyridoxal 5'-phosphate (PLP) is converted to pyridoxamine 5'-phosphate (PMP) in the presence of L-glutamate.  This coenzyme then forms a Schiff base with GDP-4-keto-6-deoxy-D-mannose and the resulting adduct undergoes a PMP-mediated beta-dehydration reaction to give a sugar enamine intermediate, which after tautomerization and hydrolysis to release ammonia yields GDP-4-keto-3,6-dideoxy-D-mannose as a product.  In vitro, is able to catalyze the formation of GDP-4-keto-3,6-dideoxymannose using GDP-perosamine rather than GDP-4-keto-6-deoxymannose as a substrate, with no need of glutamate.
What are the official names of this protein?
GDP-4-keto-6-deoxy-D-mannose 3-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NDC80_XENTR
Sequence: MRRSSVTNRQSLLPLRVQDANRMGLTTPQSKDRQGFGKLSMSKPHSGTSERKTSFFGKRMSNGTARTSQYGAFGGTEKIKDPRPLHDKAFIQQCIRQLCEFLNENGYSQTLTVKSLQGPSTKDFLKIFAFIYTFICPNYENPESKFEEEIPRIFKELGYPFALSKSSMYTVGAPHTWPQIVAALVWLIDCVKLCCVLRSENPVFEEPQMGEQSENGIDFNQLFLDYTVRCYDQFMEGRDTFEEYDADMCIRLKEAYHVDESNLEALQQESRRLLEEIERLEKEKENEPDRLASMRKLKVSLQADIQKYQNYLTEIESHSTLLEQRVSSVSEDLEATELESRAVQQENLRLKNILDNQKYSVADIERIKYEENELQQTIAKLTKDLDEDKQQLWSEELKYAKMKESVETQLSEFHKIGRKVRLIPPTAEYANGYDFQIQCNLDSEQSSLIHYRNKINVPLVEILSQSEGQIAGATNKKMGVEDMVEQLNTLIGEKKNEVKVQKDEAQKLEETYQQKVEEAEEDEKRWISEIESLEKHRQLLESGVNKSLDEALKDLQKEQQELQLVEHQTEEEMRQVENKLVRVVHAVANHVAVIEKHLEEKRLKVEREYEEFMKEDLLLDLRELLDKYKEKARVLDSPPY
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.  May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules.
What are the official names of this protein?
Kinetochore protein NDC80 homolog, Kinetochore protein Hec1, Kinetochore-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
Protein: AROK_BRUMB
Sequence: MSGTNKQTNLHRQTETIRQLLGSKVVVLVGLMGAGKSTIGRKVANMLNLPFKDADTEIETVSRMTVAELFEAYGEVEFRDLERRVILRLLDDGPMVLATGGGAYMNAETRAAIAEAGISIWINADLDVLMERVSRRQNRPLLRNSDPRGVMQRLMDERYPVYALAELHLMTRDEKKEVIAAELIEVLAAHLEKEQAASAG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.