PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_METFK
Sequence: MRLALGIEYDGAGFCGWQSQPNRLAVQDALESALSQLAGHQVRVSAAGRTDTGVHALSQVVHFDTEAVRSQTAWVRGVNTKLPRGVRVLWAKEVDPRFHARFDAYQRSYQYWLINQPVAPAVMAGKAGWFHQPLDLQAMQEAMAYLLGQHDFSAFRAAECQAKSPVKTMHHASVSAFGSSMIFDFCASAFLHHQVRNMVGALVYIGKGKYPPVFIAELLEKRDRRCSPPTFSPDGLYLTGVGYDGCWGLPGTERKLQIGIA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: BRE4_YEAST
Sequence: MKRYERDRSPTPDPDIVKGSYSQTSLRSLHELNYKNPAGISGLSFAGSPQQSVASLSQMRLENLVKDKHWEEVEDFGLEELRDGFFDAAFTKPDSKARSPNSDIDDDNGAARKKLQSGFTKLSEYVWTAIYRPIIHFPRDIRKNGVSIFKFFIAYFIAIVICVIRPSGRWIGHEFRYFLPIAVLIHHPVRNIGVQLEMTISSIIGASFGLGWSALAWYISTATKPTANYQGGILFQSLTMALLFAIWLRSVYRRFFYFTTSFSISIIFTHTVRLASSKFDLKWQIFWDFGISYLFGLLLSLLVCVCVSPHSGNAELMEHYNKCLQTTKTFLMALVDTELIKSKEQIYLAQVKMVKTLNIDLSQGFRDFVNQLTISRFDLQSLKSLRNSLTAMETSLRVLPIAPKIFNDDELKKMYEELEKYRSDSATLSKEASASPQSSGIPTRENTPSAFKPIGPGLLKNEIYINALKASFSKSIFNLILEMIFVLENLSRVLKKYESPNQKNNLDECVKILSHSHSKLKRKIYKLDVCYRDFVNSSFFSQELLNDEESVDIFLFLRYLRNSARQLVTVIHDCQVLGENIHWRIALPSYPLSRALTRLPKQCVLDEGAGNVLHYFEAKRDVDEIFERVYNTYTSRHKYNKGEEEALRLDSQGGDEKSQNRKNHTISIRAIDHNDFNFHTTQNPWRFKLWKLSRILSGDECKWTLKITFCMIFLCLPTWLPESYHWYQEFHCWWAPLTFYLLAHRRYSGNWALVMRRLICGIVGIFWGWAANQSRHFGSPYVVCTFAGLIVVPFSINFLVYRNTKSSFTALMCFTIIALEPYSKPNRHYNLTTAGIWKSTWVTGLALIIGILVSIPINWIVWPFRARTELRDSMSSLLAHLGQSYQTVADRYLYRDADDAPTDLTFAFSHIREVRLTQSLEAIRELLKKARHEPIIISNFNPEKYASLINSCQFLLSKIIEARISGAFFEIWDQDFDIETTRALLSLRRDSVSSVIFVFYILSNCFRSKNKIPRYLPNPIMSRKKLYHFIKKFSEMKDQSHSNLNSGGNSMEKNLFKKIYQQKASSSGQQQLPLPSVANSSEIDSEKMHWTEVHGIAFARAFTDISEALFQVESCAKDILGEENF
What is the function of this protein?
May be involved in intracellular vesicle transport.
What are the official names of this protein?
Protein BRE4, Brefeldin A-sensitivity protein 4.
What is the protein family that this protein belongs to?
Belongs to the BRE4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MURA1_STRP2
Sequence: MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYMDTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGYSDIIEKLRNLGADIRLVED
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).  Target for the antibiotic fosfomycin.  Involved in heteroresistance to antibiotic fosfomycin.  Heteroresistance is the ability of a clonal population to grow one or several subpopulations at a frequency of 10(-7) to 10(-3) in the presence of a higher antibiotic concentration than that predicted to be effective by measurement of the minimum inhibitory concentration (MIC) (PubMed:23571543).
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, EPT, UDP-N-acetylglucosamine enolpyruvyl transferase.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG28_KOMPG
Sequence: MICLFGNCNCQTGIFGLYDYVSFLYHSPSSCRVRLVLSLPASPNHMEEQSPKFESSFPRRTSEGPVDDVGKSPPASFYRELLANKAQQPQLSEDEEDHNPKDFLFKEDSEDELLIPDSENHNSSSTSPRKFKVENIRWGSDTLNGSILPLNSQGSNLQSLLSNVGELEHLLSKDVAKHSKYLKEQSSKVEKARANIVTNLTRLSLVLSSIFNTYQAKAQDKQAILDKIEEWEDEKKSLLDDMKEVLSTDDNADGETHKFLELASESINVENEIEALETRLKQLKIKQRTLKNECFQSQGIIESRLSNFVQAVEKIEMRERKSIEQVVQQLSENQLGYWNDNLALEVMNGLTINPGDISLVEEYEPVDILKQVESLEKPTIAADYHLPKNTNKQASRFTRQLLEFNYKCQPKLNVYPVVGLITKELKEDSAKEQEYKHRYDQVTHTLSALKDSFALIYHTEQQLQSITQSTQDLKDFQSLMNQMVESLLKTHSEADQYNLYLAKDVLAQEISIIHQALNKLNQSTEYSSVESDNVKNHDGLLFQTFSKAQERTKLPSIKSATSIRYAPSLYNSLSPTSTSKTTAKGEVNYDAGINKYTKVKEVLRSGKGNKDE
What is the function of this protein?
Required for the autophagic degradation of peroxisomes called pexophagy, but not essential for general autophagy.  Involved in resistance to elevated pH.
What are the official names of this protein?
Autophagy-related protein 28.
What is the protein family that this protein belongs to?
Belongs to the ATG28 family.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Concentration increases at the vacuolar and cytoplasmic vesicular membranes during the course of pexophagy.
Protein: TERB2_HUMAN
Sequence: MFQGQRGWFCGSVSQDLRQFWVAEGGTISDPRAADFLFSCDASHPDTLRIYQSLDYIEDNATVFHAYYLSAVANAKIKNSVALGHFILPPACLQKEIRRKIGSFIWEQDQHFLIEKHDEVTPNEIKTLRENSELATEHKKELSKSPEKHFIRTPVVEKQMYFPLQNYPVNNMVTGYISIDAMKKFLGELHDFIPGTSGYLAYHVQNEINMSAIKNKLKRK
What is the function of this protein?
Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis.  Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex.  During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA.
What are the official names of this protein?
Telomere repeats-binding bouquet formation protein 2.
What is the protein family that this protein belongs to?
Belongs to the TERB2 family.
What are the subcellular locations of this protein?
Chromosome, telomere. Nucleus inner membrane. Note=Localizes to telomeres throughout meiotic prophase I and disappears in metaphase I. In leptotene spermatocytes, localizes to telomeres that localize to the nucleus inner membrane.
Protein: YC8B_SCHPO
Sequence: MSSWFNVGILCLLRFKNVQDNKIIFEAIFEVFLHFLKIPVYMTHLGFPITPTVCLIEMLGLLLLLLIPALFTLIWIYKYIEPHSLISIPGIFVFLGLYVPFVVTLLIPIDVTWDVSLSIWRFLYWLTFVLSWIILPFVQGYMESKFSTPRSRLSDSFYKNLRYYLLLTFLTCVVIAYLRFALRTMSFSNFKELVISLTYFWGLLFVIFLLGNGFVYVPVSMWKKAFITKRAALLERQAVGVYSKLQARLESYSLPSSSISLNNGRNQSSSDFFTSSLTDHAFNPHSSPNGMSNVIALQTTWNQMVKEYNRIMLIKTAKASGSYRLYLPDSYIPIHPVVAYAFYVWILPAFRILFSIFMASMSVIIVVSEVFLHTQYSLVGIILQKFTNSSATSIFVSFLFVYYMRYCTYKSLMRTQFAPHYYYALVPFRATNTASLIYFASQLCRLTLPLCYNFVSLQPYPTQFHQFYGESIDLLPLGNLISKRYPTFILLPIIFSMISLKYRLRQFIYSITLRKSSSASSSDDFDDSSLNSENDDDLFNETSAAYLAEGRALLLGTNNAHV
What are the official names of this protein?
LIMR family protein C622.11.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: DBP8_MAGO7
Sequence: MAKIKSQRQLVSMTKDSSPRQPASEPHSSDSDSSDEESDHLDAVSSRKKRKLSVDFSQEEGDDEDDNQDESDDDDDVDEDGGKMKQPVAKPTFAFNAPSRIKRHPAKGDSERIGKGQPVTDAEMEDAVQSVAQAAGKKRILAPTDQNTTFESLGVEPWLVQSLANLAVKRPTGIQKGCIGEILKGRDCIGGSRTGSGKTIAFAVPILQKYAQDPSAIFAVVLTATRELALQIYEQFKAVSSPHVLKAALIIGGSDMRSQAIALAQRPSIVIATPGRLADHIRSSGEDTICGLRRVKFLVLDEADRLLSSKGPGSMLPHIDECMAVLPPPEDRQTLLFTATVTPEVRALKEMPTRPGKEPVHVCEVDTQVLAIPDSLKQSYIQLTVTHREHFLHEFLLTAANTERSIIIFVNRTSTAQFLHHLLRLLDHRVTSLHSKLRQQQRIDNLGRFRASAARILVATDVASRGLDIPEVSVVVNYDLPRDPDDYIHRVGRTARAGRKGEAVNFVGQRDVELVLAIEKRVGRPMEKWEEEGVNLETRVIRDSLKLVSEKKREALLNIEENREVGGRRKRQKLKLGAE
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TYPH_ECO81
Sequence: MFLAQEIIRKKRDGHALSDDEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGARVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: FLGH_RUEPO
Sequence: MMQKCLSPKTLIAALVVLSACGRADHLGKAPSFTPNTESPEHVAMLWPGLPLHTQPQRSVDRASLWSGGQNSLLGDQRAMKKGDILTVVIEIDEKAEISNDTNRSRSGSESLGVPHLLGLPQRIDEKLPEGASMSNAVAVDSSSASGGKGSVKRKEKLTLRVAATVVDVLPNGVLSITGSQELRVNFELRELLVSGYVRPEDISRQNEITYDKIASARVSYGGRGQITDVQQPRYGQQVLDMVLPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PYRG_ACTSZ
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAALLEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATIQVIPHITNEIKARVIDGAAGYDVAIIEVGGTVGDIESLPFLEALRQLAVQVGRERTIFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMIPANERSKIALFCNVPEKAVISLKDVESIYQIPALLQSQGLDEFVCNRFHLEGKPADLSEWEQVLYRQANPTGEVTIGMVGKYVELPDAYKSVNEALKHAGLTNRLTVHIKYIDSQDVETKGTDVLKDLDGILVPGGFGYRGVEGKILTAQYARENNIPYLGICLGMQTALIEYARNVAGMKDANSSEFVKDCAYPVIGLITEWQDAEGNVEQRSENSDLGGTMRLGAQQCHLIEGSKARELYGKETIEERHRHRYEVNNTLLPQIEAAGLKVTGLSADRKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAKENQKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HSLO_SHELP
Sequence: MSKDILNRYLFDNADVRGQIVQLEKSYQEILSAHTYPEAIARLLGELMAATSLLTATLKFDGDISVQVQGNGPVSLAVINGNNLQQLRGVARWEGEVAKDASLQQLMGQGHMVITLTPNNGERYQGVVALEKETLAECLEQYFLQSEQLPTAIRLFANGKQAAGMLLQVLPGEDEHNEEFEHLEQLTSTIKAEELFELEATEVLHRLYHQEEVRLFDPIEVTFSCTCSRERSGQALKTVAKEELDAILAEQGKIEMGCEYCNSSYSFDSIDIEALFKNAPKADTQQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIPD_SALPA
Sequence: MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTDIISLSQAATKIQQAQQTLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQTGSGMTTATKAEAEQWIKELNLPDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSALELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
What is the function of this protein?
Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization.  Probably acts by modulating the secretion of SipA, SipB, and SipC (By similarity).
What are the official names of this protein?
Cell invasion protein SipD, Salmonella invasion protein D.
What is the protein family that this protein belongs to?
Belongs to the invasin protein D family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity).
Protein: EIF3M_USTMA
Sequence: MSAADLVTVLAEGTFEEQIVEVSAFLSRSQPEASRNDFISKFQQLALDAEPAEPAEPAVSTEATEPASAPDAAKKQQTVQQLVSEIVTLGEGSDRELEGVYNLIFSLISSTDQQTQLVPQLLSAVSKDSAAAATGAGGADKSNVRYRILSNLFNSLEATSALRLQTFNALLSLVAANDDLDYLTSALTALPQWLAQWSVSETEKASCLESVAKALEGAEKEHGQTSKAYQFLVLHLRYISTLPASASTKEAAERTVAAALRLPRLYEFEDLLHVQAVLDLKSASSPIFDLLKIFVGGTTADFSAFASSHSSEFQRLNLSHDDLLHKIRLLDLADLCALRVSADVSYASIAKTLNIEHDQVELWVIDVIRAGLVSGKLSQVNDAFRVYKSTHRQFGKEQWQSLEQRLVQWQNSISSIIESIAATRGGKLPDGAPVAAELATA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_SHIBS
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: FABZ_PROMP
Sequence: MEQQLSTENNQLSSEEILGLLPHRFPFALIDRVIEHVPGKKAVALKNVTINEPQFQGHFPERPLMPGVLIVEAMAQVGGIIVTQMPDLPKGLFVFAGINNVKFRRPVVPGDQLVITCELLSIKRQRFGKVKGEAHVDGKLVCSGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_SALPC
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKVRTRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIRMLQQTIEQALLDQGRITEKTGQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: TRPD_ACIC1
Sequence: MTADTPSWPEVLSALLARRDLTEAEAAWAMHQIMSGEATDAQIAAFAVALRAKGESAEEVSGLSSVMLALAAPVPPIGEALDIVGSGGDRAHTVNISTMAAIVAAATGVVVAKHGNRAASSACGSADLLEALGVAIDLDGAGVARCIERAGIGFCFAPVFHPSLRYAAVARREIGIPTVFNFLGPLTNPARPTASAVGVADPRMAPVVAGVLARRGMRALVFRGDDGLDELTVTTTSTVWVVRDGSVQEVAFDPRAVGIEPADTAALRGADARHNAAVARAVLSGERGPIRDAVLLNAAAGLTAFDTPRPDQLVDQISAAMTRCAAAIDTGKAAQLLDAWVEASQAARGVDADRS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: BAAT_RAT
Sequence: MAKLTAVPLSALVDEPVHIRVTGLTPFQVVCLQASLKDDKGNLFNSQAFYRASEVGEVDLERDSSLGGDYMGVHPMGLFWSMKPEKLLTRLVKRDVMNRPHKVHIKLCHPYFPVEGKVISSSLDSLILERWYVAPGVTRIHVKEGRIRGALFLPPGEGPFPGVIDLFGGAGGLFEFRASLLASHGFATLALAYWGYDDLPSRLEKVDLEYFEEGVEFLLRHPKVLGPGVGILSVCIGAEIGLSMAINLKQITATVLINGPNFVSSNPHVYRGKVFQPTPCSEEFVTTNALGLVEFYRTFEETADKDSKYCFPIEKAHGHFLFVVGEDDKNLNSKVHAKQAIAQLMKSGKKNWTLLSYPGAGHLIEPPYSPLCSASRMPFVIPSINWGGEVIPHAAAQEHSWKEIQKFLKQHLNPGFNSQL
What is the function of this protein?
Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12951368, PubMed:624713).  More efficient at taurine conjugation of cholyl CoA than glycine conjugation (PubMed:12951368, PubMed:624713).  Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism (By similarity).  This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption (By similarity).  May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids (By similarity).  In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (By similarity).
What are the official names of this protein?
Bile acid-CoA:amino acid N-acyltransferase, BACAT, BAT, Bile acid-CoA thioesterase, Choloyl-CoA hydrolase, Glycine N-choloyltransferase, Kan-1, Long-chain fatty-acyl-CoA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Peroxisome. Cytoplasm, cytosol.
Protein: GBRA4_MOUSE
Sequence: MVSVQKVPAIALCSGVSLALLHFLCLAACLNESPGQNSKDEKLCPENFTRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPPEVPAAPVLKEKHTETSLQNTHANLNMRKRTNALVHSESDVKSRTEVGNHSSKTSAVQESSEATPKAHLASSPNPFSRANAAETMSAAARGLSSAASPSPHGTLRPASLGSASTRPAFGSRLGRIKTTVNTTGAAGNVSATPPPPAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CLCC_ARATH
Sequence: MDDRHEGDHHDIEVEGGALHGFERKISGILDDGSVGFRQPLLARNRKNTTSQIAIVGANTCPIESLDYEIFENDFFKQDWRSRKKIEILQYTFLKWALAFLIGLATGLVGFLNNLGVENIAGFKLLLIGNLMLKEKYFQAFFAFAGCNLILATAAASLCAFIAPAAAGSGIPEVKAYLNGIDAYSILAPSTLFVKIFGSIFGVAAGFVVGKEGPMVHTGACIANLLGQGGSKKYRLTWKWLRFFKNDRDRRDLITCGAAAGVAAAFRAPVGGVLFALEEAASWWRNALLWRTFFTTAVVAVVLRSLIEFCRSGRCGLFGKGGLIMFDVNSGPVLYSTPDLLAIVFLGVIGGVLGSLYNYLVDKVLRTYSIINEKGPRFKIMLVMAVSILSSCCAFGLPWLSQCTPCPIGIEEGKCPSVGRSSIYKSFQCPPNHYNDLSSLLLNTNDDAIRNLFTSRSENEFHISTLAIFFVAVYCLGIITYGIAIPSGLFIPVILAGASYGRLVGRLLGPVSQLDVGLFSLLGAASFLGGTMRMTVSLCVILLELTNNLLMLPLVMLVLLISKTVADCFNRGVYDQIVTMKGLPYMEDHAEPYMRNLVAKDVVSGALISFSRVEKVGVIWQALKMTRHNGFPVIDEPPFTEASELCGIALRSHLLVLLQGKKFSKQRTTFGSQILRSCKARDFGKAGLGKGLKIEDLDLSEEEMEMYVDLHPITNTSPYTVLETLSLAKAAILFRQLGLRHLCVVPKTPGRPPIVGILTRHDFMPEHVLGLYPHIDPLK
What is the function of this protein?
Voltage-gated chloride channel.
What are the official names of this protein?
Chloride channel protein CLC-c, AtCLC-c, CBS domain-containing protein CBSCLC4.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL30_MYCGI
Sequence: MAELKITQVRSTIGARWKQRESLRTLGLRKIRQSVVREDNAQTRGLIKTVHHLVEVEEVKA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PYRD_XYLFM
Sequence: MYSLFRPLLFTCDTERAHDISLRTLDIAYHSGALPLLTRHTRPLPTTAFGLNFPNPVGLAAGLDKNGTHIDALFALGFGFIEIGTTTPRPQAGNPKPRLFRLTQQQAVINRMGFNNLGVDALVRNVAGARRRNGPLGINIGKNKDTPNEQASNDYRYCLERVYALADYVTINLSSPNTAGLRALQEEQTLRRLIGELRETQETLAAKHGRHVPMLIKMAPDLSDSDIDAAARVLNEMSVDGVIATNTTVTRPLLRQHPLASEAGGLSGAPLLGQSTLVLRRLRTHLPETIDLIGVGGICCGADAGAKMAAGASLVQCYTGLIFKGPQLVGECVEAIRRRLEASSSGRENTQ
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ANGL4_MOUSE
Sequence: MRCAPTAGAALVLCAATAGLLSAQGRPAQPEPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALERRMAACGNACQGPKGKDAPFKDSEDRVPEGQTPETLQSLQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLAPTHLDNGVDKTSRGKRLPKMTQLIGLTPNATHLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGNRGSQLAVQLQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHSIPRQRQERKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS
What is the function of this protein?
Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism.  Has higher activity in LPL inactivation than the uncleaved protein.
What are the official names of this protein?
Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4.
Protein: RL14_NATPD
Sequence: MEALNADVTQGLEKGSLITCADNTGARELKVTSISGYSGTKNRHPKAGLGDKITVSVTKGTPEMRRQVLEAVVIRQRKPIRRPDGTRVKFEDNAAVIVDENEDPRGTELKGPIAREVAERFGSIASTATIIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.