PharMolix/UniProtQA huggingface dataset:
Protein: Y027_MYCPN
Sequence: MDKNTILEFCFFGDRYQLMALKNPNKLVKNKQVKAAFNVFMKHRTTLSATNYMAQIVENFEQFLEYIHDKLQPGKLLALLFKNKQFLGWFCVGQWGNMPVLSFWIDPSQQQSGVALETISFFLKYYQRTLQPRELVWSFYESNQRSRHLANKLGFPSLFYFKKAEPNAPKVYFGTKDFKGESVIETKPYLGWGSGWKVNQMLKPTKNLTVNLINIGFDAYADSQKALLAWFKTHKLTKGQVEVFFNYELCCLCISYNHKQSWVVYSFQQLLAKR
What are the official names of this protein?
Uncharacterized protein MPN_027.
Protein: D3_FOWPN
Sequence: MEIHRLNSYTSVDYLCNSSNNVYILLGDTDEFINKRIILLMNNIELYYVYEISVNDEDELYHSFITSNVVCPIKQRINLMLYKEYKKVIGSCVINNEGNIKMYSQPDKLHVYVLCYRCNGDIKTITMIKCHQLLKPEKEIVIDGYQVNDSSFFYTSPNLIKQINMDKSDLFYKNILLRKEINCLIRKQESSNLYCILNKHIVSLSDTDIWKVIISDELFDSSDIEKLVKFDYDRDKFHAFVRAWYSGQLSNCKEENETIKTVYEMIEKRI
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions (By similarity).
What are the official names of this protein?
27 kDa core protein.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae D3 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: ATP6_COLP3
Sequence: MSSGAVLTSQEYITHHLSNLKVGEGFWAVHLDSLGWSVFLGLVFLTIFRSVAKKATSGVPGKLQCAVEMVVGFVDDSVKSTFHGKNALIAPLSLTIFVWILLMNSMDWVPVDLLPHLIHWVTGMPLGDIYMKPVPTADPNITFGLALGVFILIIYYSIKVKGVGGFMKELTTQPFGHWSLYPVNFILETVTMLARPLSLALRLFGNLYAGELIFLLIATIGVFQLPVHFLWAAFHLLVIPLQAFIFMMLTIVYLSLAHEDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NSN5B_HUMAN
Sequence: MATLLAWVGVSCCELAEEDFLAVSPLDPRYREVHYVLLDPSCSGSGMPSRQLEDPGAGTPSPVRLHALAGFQQRALCHALTFPSLQRLVYSMCSLCQEENEDMVPDALQQNPGAFRLAPALPARPHRGLSTFPGAEHCLRASPKTTLSGGFFVAVIERVEMPT
What are the official names of this protein?
Putative NOL1/NOP2/Sun domain family member 5B, Williams-Beuren syndrome chromosomal region 20B protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
Protein: RSMB_HUMAN
Sequence: MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077).  As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (PubMed:12975319).
What are the official names of this protein?
Small nuclear ribonucleoprotein-associated proteins B and B', snRNP-B, Sm protein B/B', Sm-B/B', SmB/B'.
What is the protein family that this protein belongs to?
Belongs to the snRNP SmB/SmN family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes.
Protein: LYSC_PHOVI
Sequence: MKALLLLGLLLLSVTVQGKIFERCDLARTLKRLGLAGFKGVSLANWMCLAKWESNYNTKATNYNPGSRSTDYGIFQINSRYWCNDGKTPRAVNACHIPCSDLLKDDITQAVACAKRVVSDPNGIRAWVAWRAHCENQDVSQYVRNCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDCB_PSESM
Sequence: MSALQRTPQPASLAERLADLAVDALIDEADLSPKPALVDRCSNGAHTDLHLGLMHSSALSLWPTFKLMADAAAQFQAVGEPLREALGRLGREGEATMLRTTSGVNTHRGAIWALGLLVTAAALDPQDCGPDAVCQRAASLALIKDRQVLAQNSHGSEVVRRYGVMGAREQAQHGFPAVIRCALPQLQRSRAAGSGEQNARLDALLAIMTTLADTCVLHRAGLEGLQTMQNGAQRVLDAGGSASLAGRRALNQLDQQLLALNASPGGAADLLAACLFIDGLEPALGPVSRSA
What is the function of this protein?
Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: RBL_VIGUU
Sequence: PQTETKASVGFKAGVK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DHH1_YEAST
Sequence: MGSINNNFNTNNNSNTDLDRDWKTALNIPKKDTRPQTDDVLNTKGNTFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLEKVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLNETVHILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFSATFPLTVKEFMVKHLHKPYEINLMEELTLKGITQYYAFVEERQKLHCLNTLFSKLQINQAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLTRGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGTEIAAIPATIDKSLYVAENDETVPVPFPIEQQSYHQQAIPQQQLPSQQQFAIPPQQHHPQFMVPPSHQQQQAYPPPQMPSQQGYPPQQEHFMAMPPGQSQPQY
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1 (PubMed:11780629, PubMed:12032091, PubMed:11696541, PubMed:12730603, PubMed:15703442, PubMed:15706350).  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs (PubMed:15166134).  May also have a role in translation and mRNA nuclear export (PubMed:12930949).  Required for sporulation (PubMed:12930949).  Blocks autophagy in nutrient-rich conditions by, at least partly, binding and repressing the expression of a set of ATG genes, including ATG3, ATG7, ATG8, ATG19, ATG20, ATG22 and SNX4/ATG24 (PubMed:26098573).
What are the official names of this protein?
ATP-dependent RNA helicase DHH1, DExD/H-box helicase 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: NUCL_HUMAN
Sequence: MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
What is the function of this protein?
Nucleolin is the major nucleolar protein of growing eukaryotic cells.  It is found associated with intranucleolar chromatin and pre-ribosomal particles.  It induces chromatin decondensation by binding to histone H1.  It is thought to play a role in pre-rRNA transcription and ribosome assembly.  May play a role in the process of transcriptional elongation.  Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
What are the official names of this protein?
Nucleolin, Protein C23.
Protein: ENV_HV1ET
Sequence: MKVMGIQRNCQQWWIWGILGFWMLMICNGMGNLWVTVYYGVPVWKDASPTLFCASDAKAYDTEVHNVWGTFACVPTDPSPQELGLENVTENFNMWKNDMVEQMHQDIISLWDQGLKPCVKLTPLCVTLNCNAIKNNTKVTNNSINSANDEMKNCSFNITTELRDKKRKAYALFYKLDIVPLNNGSTDYRLINCNTSTITQACPKVSLDPIPIHYCAPAGYAILKCRDKTFTGTGPCHNVSTVQCTHGIKPVVSTQLLLNGSIAEGETIIRFENLTNNAKIIIVQLNESVEITCTRPSNNTRESIRIGPGQTFYATGDIIGDIRQAHCNISEEKWNKTLQKVKEKLQKHFPNKTIEFKPSSGGDLEITTHSFNCGGEFFYCNTSNLFNSTKLELFNSSTNLNITLQCRIKQIINMWQGVGRAMYAPPIEGIIMCRSNITGLLLTRDGAKEPHSTKEIFRPEGGDMRDNWRSELYKYKVVEIKPLGVAPTKPKRRVVEREKRAALGALFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLKAIEAQQHMLQLTVWGIKQLQTRVLAIERHLRDQQLLGIWGCSGKLICTTAVPWNSSWSNKSQEEIWDNMTWMQWDREISNYTDIIYNLLEVSQNQQDKNEKDLLALDKWENLWNWFNITNWLWYIKIFIMIVGGVIGLRIIFAVLSIVNRVRQGYSPLSFQTLIPHPRGPDRLGGIEEEGGEQGRDRSIRLVNGFLAIFWDDLRSLCLFSYHRLRDLILIAARTVELLGRSSLKGLQRGWETLKYLGSLVQYWGLELKKSAINLLNTTAIVVGEGTDRFIELIQRIWRAFCNIPRRIRQGLEAALQ
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: CINA_STRP7
Sequence: MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPMVLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVRHIAVMHAFNLVRKALLSD
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: FMOD_BOVIN
Sequence: MQWASILLLAGLCSLSWAQYEEDSHWWFQFLRNQQSTYDDPYDPYPYEPYEPYPYGGEEGPAYAYGSPPQPEPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQISSIQEGVFDNATGLLWIALHGNQITSDKVGKKVFSKLRHLERLYLDHNNLTRIPSPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLHHNEIQEVGSSMKGLRSLILLDLSYNHLRKVPDGLPSALEQLYLEHNNVFSVPDSYFRGSPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVSTNLENLYLQGNRINEFSISSFCTVVDVMNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI
What is the function of this protein?
Affects the rate of fibrils formation.  May have a primary role in collagen fibrillogenesis (By similarity).
What are the official names of this protein?
Fibromodulin, FM, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SYA_SYNPW
Sequence: MAVARSSRTDAARPRTGAEIRDAFLAFFEERGHKRMPSASLVPEDPTVLLTIAGMLPFKPIFLGQQERPAPCATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWELSTGVFGLDPKNLVVSVFRDDDEAEQIWREVVGVNPKRIIRMDEEDNFWASGPTGPCGPCSEIYYDFKPELGDDGIDLEDDDRFIEFYNLVFMQSNRDAEGTLTPLANRNIDTGMGLERMAQILQKVPNNYETDLIFPLIQAAAERAGVDYHQLDEKGKTSLKVIGDHSRAVTQLISDGVTASNLGRGYILRRLLRRVVRHGRLLGIDKPFLQAMGEASIALMQSAHPQLSERREVILAELQREEARFLETLERGEKLLADVLAAKPKQISGEQAFELYDTYGFPLELTQEIAEEHGLAVDLAGFETAMEQQRQRAKAAAVSIDLTLQDAIDQVAAGLQDTEFRGYEQLEQSSSIQALVVNGEPAQSAVAGDAVQVVLDVTPFYGEGGGQIGDRGTLVADGQAGDGLIVMVESVSRNRSVFVHSGRVQRGALAVGDVVHGRVDRACRRRAQANHTATHLLQAALKQEVDPGIGQAGSLVSFDRLRFDFHCPRAVTAEELERIESLINGWIADAHALEVQEMAIEKAKAAGAVAMFGEKYADVVRVVDVPGVSMELCGGTHVANTAEIGLFKIVSESGVAAGIRRIEAVAGAAVLPYLNERDAVVKQLGERFKAQPGEIIERVTALQDELKATGKALAAAQAELAVAKSAALATKAVAVGDFQLLVERLDGVDGTGLQGAAQSLADQLGDGAAVVLGGLPDPADQGKVILVAAFGKAVIAQGQQAGKFIGGIAKLCGGGGGGRPNLAQAGGRDGAALASALEAASHQLRESL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFB1_ORNAN
Sequence: MNAHVLLLCTILFLLVHTPPVLGGMKEKCVTMGGYCRKQCRVQDALSGYCRNENPCCVRRVLMEDG
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Defensin-B1, DefB1, OaDefB1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AA1R_CHICK
Sequence: MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
What is the function of this protein?
Receptor for adenosine.  The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
What are the official names of this protein?
Adenosine receptor A1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BR2A_PELLE
Sequence: GILDTLKNLAISAAKGAAQGLVNKASCKLSGQC
What is the function of this protein?
Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
What are the official names of this protein?
Brevinin-2Ea.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: H2B2_KLULA
Sequence: MAPKAEKKPASKAPAEKKPAAKKTSSSVDPSKKRTKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATESSKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MYOD1_RAT
Sequence: MELLSPPLRDTDLLGPDGSLCSFATRDDFYDDPCFDSPDLRFFEDLDPRLVHVGALLKPEEHAHFPTTVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDAAYYSEASSEPRPGKSAAVSSLDCLSSIVERISTDSPAAPSLLLPDAPPESPPGPPEETSSSDAEQGTQTPSPDSTPQCPAGSKPNPIYQVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis.  Induces fibroblasts to differentiate into myoblasts.  Interacts with and is inhibited by the twist protein.  This interaction probably involves the basic domains of both proteins (By similarity).
What are the official names of this protein?
Myoblast determination protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYK2_ECOLI
Sequence: MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK
What is the function of this protein?
Can also synthesize a number of adenyl dinucleotides (in particular AppppA).  These dinucleotides have been proposed to act as modulators of the heat-shock response and stress response.
What are the official names of this protein?
Lysine--tRNA ligase, heat inducible, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_XYLFA
Sequence: MSGLIAYCRQGFEPELAAELRDRAVLLGIAGDIHAQRNHGFVLLRCDPLHVDTLLQQLHWRRLIFARQTLRLHAELKTLNSRDRIAPILAALPKTPCFGDLWIEYPDSDMGKPLAGLARSFGNALRPVLRSAGRLSAQLHPQWPRLHVCFLSGDHVLLGSTRSVDSAPWQLGIPRLKLLPEAPSRSALKLEEALITLLTSNEREAKLRPGMRATDLGAAPGGWTWVLIRQHLRVTSIDNAVLRPSLLNHPLVQHVRADGFRWTPPRPMDWMVCDMVEQPRRVAERMAVWLREGWCRHMIFNLKLPMKKRWDETRLCLERFETQAVVPLTLRAKQLYHDREEITVYASNNAR
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAE2_MYCTU
Sequence: MTQVLRAALTDQPIFLAEHEELVSHRSAGAIVGFVGMIRDRDGGRGVLRLEYSAHPSAAQVLADLVAEVAEESSGVRAVAASHRIGVLQVGEAALVAAVAADHRRAAFGTCAHLVETIKARLPVWKHQFFEDGTDEWVGSV
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit 2, MPT synthase subunit 2 2, Molybdenum cofactor biosynthesis protein E 2, Molybdopterin-converting factor large subunit 2, Molybdopterin-converting factor subunit 2 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: ESFLA_ARATH
Sequence: MSSLYFAILCLFMIFLVPLHEFGNAQGSEAELQLDPSMCLRVECAKHRNQKWCFCCAGLPRTCFLDKRGCTSVCKRESPSMA
What are the official names of this protein?
EMBRYO SURROUNDING FACTOR 1-like protein 10.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: HMUV_STRCO
Sequence: MRGVKLPRLVPSRPVPPPPAAPGEVLAAAGGLRVHLGGRPVLDGVDVEVRAGEVLALVGPNGAGKSTLLGALAADVPAAEGVVRVHGRPVSDWSAPELALRRAVLPQSASLSFPFAVEEVVRMGRAPWAGGDRADEDEAAVAEAMARTEVAGFAGRPFSALSGGERARVALARVLAQRAPLLLLDEPTAALDLRHQELVLRLCRERARAGDAVVVVLHDLALAAAYADRVALLRSGRIAAGGPPSEVFAQGLLSEVYDQPVEVFPHPRTGALLVVPHRSP
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NDHO_PROM4
Sequence: MTDSSFSVPKPKPLKKGSLVLVNREAYESSLEALASDALPPQYIFEGPGEILMVKGDYAQVRWRRPVPDVWLRIDQLKAWAE
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS3_HYPBU
Sequence: MVLIKRYFIKKAMVQTQIDEYLAKRFYRAGYAGVQIIQFPLGTRVIIYAERPAMIIGRRGETIRQLAAIFEHEFGLSNPQITVRRVENPDLNARVVASRIAVLLERGAYYRRVANVMARRVLNAGAIGVQIVISGKLRTERARYEKVRRGKVYTTGHQVEYMVDRAVMHVTLKPGVLGIEVMIVKPAKPSDYVRIKQPEEVKEFIEQVRSELEKARAAEAAAAVAQQGEVVGEAPNTPLEEQGQKQG
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.