PharMolix/UniProtQA huggingface dataset:
Protein: STP_SHV24
Sequence: MASEPNLRYPTEETGDRGPQGPPGPPGPQGPPGPQGPPGPQGPPGPQGPPGPQGPPGPQGPPGPPGPPGPSGLPGLFVTNLLLGIIILLLLIIVAILLVSKLVVN
What is the function of this protein?
Acts synergistically with Tip to stimulate NF-kappa-B activity and interleukin-2 gene expression by binding to host TRAF proteins.  Activation of NF-kappa-B protects lymphocytes from apoptosis, thereby facilitating viral induced cell transformation.
What are the official names of this protein?
Saimiri transformation-associated protein, Collagen-like protein, stpC.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: BPT_HALHL
Sequence: MSRSRITLLRTHCHECAYVSGRTARLEFLSPTLRLNDHRYQLLLEQGFRRSGPYVYRPHCPGCKACQSLRIPVARFRPRRRHRRCQRANANLHVTACPPVMTQEHLALYRRYIDHRHPRSSMANPDHAEAEGFLAAPWCTTVFYELRTEAQGSLLAVAVTDVLPDALSAVYTFYAPEAEHRGLGNLAVLWQLSEARRLGAQHLYLGYWIADAPAMAYKASFRPHEIFDGRGWRAQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFED_YERPE
Sequence: MNMLFSLISEPFAYPFMQRAIVAAIVTGVVCAILSCYLVLKGWSLMGDAISHAVLPGIVLAFWLGIPLVIGAFVSGIFCAVATGYLKENSRVKEDTVMGIVFSGMFAFGLVLFSRIDTDQHLSHILFGNMLGISLTELKQTLWIAGFTLLVVLLKRKDFMLYCFDPNHARVIGLPVKFLHYGLLCLLALTIVASLQAVGVILVIAMLIAPGIIAFMICRSFDQMLVVATLVSVVACVLGTLISFHIDGATGPCIVIIQALFFVVALIYNHIKPIKDRKMAPLTKAVNPENTAPSNLP
What is the function of this protein?
Part of an ATP-driven transport system YfeABCD for chelated iron.
What are the official names of this protein?
Chelated iron transport system membrane protein YfeD.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMK_PSEAB
Sequence: MKIAVLSRNPRLYSTRRLVEAGRERGHEMVVIDTLRAYMNIASHKPQIHYRGQPLEGFDAVIPRIGASVTFYGCAVLRQFEMMGVFPLNESVAIARSRDKLRSLQLLSRKGIGLPVTGFAHSPDDVPDLIEMVGGAPLVIKLLEGTQGIGVVLCETEKAAESVLEAFMGLKHNIMVQEYIKEAGGADIRCFVVGDKVIASMKRQAAPGEFRSNLHRGGSASLIKITPEERMTAIRAARVMGLNVAGVDILRSNHGPLVMEVNSSPGLEGIESTTGKDIAGIIIQYLEKNGGPHLARTKGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: CDII_ENTCC
Sequence: MFGIFSKGEPVSMEGELVQPSSIVINDYEEELHLPLSYWDIKDYKNSWLKSLGEGLSNKTHSALAVSMYEPEKTNFIFTWVLYFEDEKVYVQNNVIFLEECHGFSPENINKFIESRTTHDGDGMKISEWHTDLNSVLDFYHSLNN
What is the function of this protein?
Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system.  CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion.  Protects cells against the 16S rRNase activity of CdiA-CT, its cognate toxin protein, but not against the toxic effects of a similar rRNase, non-cognate CdiA-CT from E. chrysanthemi strain EC16.
What are the official names of this protein?
Immunity protein CdiI.
Protein: PCTM1_ECOLX
Sequence: MEIEKNKEKIKLQFDIIKRTDGYISTTNNKAALLLAVNGATATILSNKVGYFAGLFHENCLYMVIFFLLLFMISIFIFMSVLLSLKSIIPNMRGVKEKWDSTDSNVSFVYISSNNDGKNYYKKYLMESEDGLLLDMCEQSFILSCIAKQKFLFFSSAVSWIKRAYACIIVLVIFKFVDYVNGALL
What is the function of this protein?
The effector component of a two-gene Pycsar system.  Expression of this and adjacent cytidylate cyclase EcPycC (AC P0DV24) confers resistance to bacteriophage P1 and T5; this protein is required for resistance.  When cells expressing the Pycsar system are infected by phage T5 at low multiplicity of infection (0. 2 MOI) the culture survives, at 2. 0 MOI bacteria enter growth arrest.  The same cells enter growth arrest after exposure to 250 uM cCMP but not cUMP; this effector protein responds only to cCMP, usually produced by its cognate NTP cyclase.  Some of the cells treated with cCMP have abnormal membrane protrusions, probably due to effects on membrane integrity.
What are the official names of this protein?
Pycsar effector protein EcPycTM, EcPycTM.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YG007_YEAST
Sequence: MLPSISFDYIKRPNIVLFSNVLSLSSNI
What are the official names of this protein?
Uncharacterized protein YGL007C-A.
Protein: CYSN_SALSV
Sequence: MNTILAQQIANEGGVEAWMMAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: GCH4_BURM1
Sequence: MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVLTESGDVQPTVGVWNLDVRLPAEQKGTHMSRFVALLEENRAPLTIERFRAMIASMLEKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAARLDADARIVAYVLEAENFESIHNHSAYALIERDKRHAA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: PRIA_BUCAP
Sequence: MIIVKVVLPLPIRKYFKYFMPDSMCPIIGGRIVVPFRSKDIVGIVISFCNKKNISNLNLAFVKSCIDTESIYSDVVFSILIWLSRYYYFPIGSIFFSILPKYLKKICLIDNKNYKFAILRKTKYKDFKTFNLLFFCKKKSFIDKDLEKYTFFDFFLKKNFLQKSCKNYFYHENIPHIYQNYLIKKKFFLNKKIIFIINKILMKNCFTSWLITKNNFYLKVKFYLGLIKECLSKNLQILILVPFVKDIYQILFFLKKYFNVYIDIIHSQLNNEDYLKKWIRTKSGKNSIIIGTKNSVFFPFLKLGLIIVNQEHHLNYRNLDQCRYNVRDIAILRAYKQNIPIILDSDTPSLRTLYNILHKKCFYIKFIKNKKTFFLKNNVIDLRKERIKIGLSSTLINEIFNNIQKNYPVLLVLNKFSFVFFGLICRRCGKIEKCHICNDYFETKKYDNFLFCRNCLIKIKKPLFCYNCKNFSLIVFDFGIKKIKNSFKKIFPNINLFFLLSLKKNKTKKLKIQFFKFPISNACIIITTEKISQHYYFPYVRFIALTNVDHYFFSFHFCSIEHFLQFYFNLINLTGENKKLLKIFIQTSYPNNKFLLNLCSSDYFLFCRKILSLRKKYFLPPWNFQVIFYSSSKFFEKSFIFLECIQIILKKQSKRDNVSLWFVGPHPVFSLKDRKKCFYQLLIHSPSRTYLKKILKESINIVQCFSISQNVQWFLDIDIY
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: SYN_HAEIN
Sequence: MSKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIENYESEILRLTTGCSVIVTGKVVESPAEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNIIGAVARVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRVSTLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDYTDAIDVLLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDEKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWWYRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_CLOB1
Sequence: MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNNSIPYYIIGNGSNLLVRDGGIRGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNLGGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDKDGNVFLLNKEQLDLGYRMSAIQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRTEKQPLEYPSAGSTFKRPEGHFAAKLIEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFEVDLHTEVRIIGEENN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_PSEF5
Sequence: MVIKPRVRGFICVTTHPVGCEANVKQQIDYVTQQGAIDAGPKNVLVLGASTGYGLAARITAAFGCGANTLGVFFERGSVDGKLGTAGWYNTAAFHKFAEEKGLYAKSINGDAFSDAVKAETIETIKRDLGKIDLVVYSLAAPRRTHPKTGEVLSSTLKPLGKSVTLRGVDTDKEIVKETTLQPATQEEIDGTVAVMGGEDWQMWIDALHEAGVLAEGAKTTAFTYLGEKLTHDIYWNGSIGEAKKDLDQKVIGMRQQLAGLGGDARVSVLKAVVTQASSAIPIMPLYLSLLFKVMKEQGSHEGCIEQVYGLYKDSLYNSEPVIDQEGRLRADYKELQPAVQDRVKQLWDQVTSENLYEMTDFVGYKQEFLRLFGFEIEGVDYEADVDPDVKISNLIQL
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: Y454_RHOPS
Sequence: MTTSSERPETSVDRKLLEILVCPVTKGPLEFDAARQELISRGAKLAYPIRDGIPIMLPEEARKLG
What are the official names of this protein?
UPF0434 protein RPD_0454.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: HIR1_DEBHA
Sequence: MHILKLPWFGHKAENKQIECYSVSINSDGSRLASGGLDGNVKIWDTKSILHFKNYEAEPATLNNKNGINLDTLNSDIIRRPLCSMSRHNGVVTSVKFSPDGRFLASGSDDKIVLIWEKDEEQANRPKQFGEAEADLEHWTVRKRLVAHDNDIQDICWSPDGSLLVTVGLDRSIIIWNGLTFERIKRYDIHQSMVKGIVFDPANKFFATASDDRSVRIFRYYRKLSESSINNYEFQMEHIVIDPFKKSPLTSYFRRMSWSPDGQHIAVPNATNGPVTSVAIINRTNWGTDISLIGHEAPCEVCCFSPRLFEYDDSNDSQKNKNGMGNFTTILATAGQDQNLVVWTTRQSKPLVVAHDIVSGSITDMCWAPDGQTLYFSCLDGSITCVSFEDNELGKVVSENMNDLQLHRYGADRESATFPESVEQLLLEEKSEVTEHKENKKLAITKPPTTILKSRPEEVRPKEVSPKINNLTPKQVNKLTQSITITKNGKKRVAPLLVSSSSKISVPVLGTSGKVTKKFQIGSKLSQTSYFLPRLGVSTSVQGLKSKNLVHEFNQTNEANNDDQDNDNEDMGIDSAKVNDNPKDALNQSVSDATLRRQRNKIKRAILETRYPSCFQLISTLPDNLFNNQAILNSKVNQILNNNFNSKRENNNEIISGSSIDAIDEDLIFSVIVTGIQSIEDRSSIIINDAYDANTSITSIVEVRNGPSWKVNEDDITDFEYGDRIDFQDPTRVIVSNDQNHTKRSYTVFFPYKVQHVLPIIKNRILTFYVLASFNGTIQIISAKSGKYVTASMEVGNNVILLKQEGDYLMCVTNQGLIFVWKLPNLPVERFLTGVVRGISLAPILNNMVEVPSIEKKNLNKRHANIPQLMMPNVRKLDVDTRNGSPLAILEDNNEVYKFSLDLMVWIKVVDPWYFLALTDSPVDSFKTGNCIDSLLHKSYKSFEEDVKRSKIGLYIYNNSEETNELQKVMEARFKQSIELAGQIA
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: B29K_PORGN
Sequence: ANEAKVVLVADNVQGDN
What are the official names of this protein?
29 kDa immunogenic protein.
Protein: CYB_AKOPA
Sequence: MKILRKNHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGMCLVIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLLETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAFALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTTKDLLGIFLLLLVLMILALFFPNVLGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILATFPLLNTSKQHGLIFRPVTQVIYWIFIANLLVLTWIGGQPVEYPFTTIGQIASITYFAIIIILIPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSTS3_MYCAV
Sequence: MKLNRFGAVLSVLSAGALVLSGCGSDNNGAGAGAAGSSSSKVSCGGKKALKASGSTAQANAMTRFVNAFEQACPGQTLNYTANGSGAGISEFNGKQTDFGGSDSPLAPSEYAAAQQRCGSPAWNLPVVFGPIAITYNVAGLNSLNLDGATAAKIFNGAITTWNDPGIQALNPGVALPAEPIHVVFRNDESGTTDNFQKYLDAAADGAWGKGAGKTFKGGVGEGAKGNDGTSAAIKATEGSITYNEWSFAQAQKLNMAKIITSAGPDAVAISADSVGKTIAGAKISGQGNDLVLDTLSFYKPTQAGSYPIVLATYEIVCSKYPDPQVGTAVKAFLQSTVGAGQNGLADNGYIPIPDAFKSRLSAAINAIT
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS 3, PBP 3, PstS-3.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CST9P_HUMAN
Sequence: MWSLPPSRALSCAPLLLLFSFQFLVTYAWRFQEEEEWNDQKQIAVYLPPTLEFAVYTFNKQSKDWYAYKLVPVLASWKEQGYDKMTFSMNLQLGRTMCGKFEDDIDNCPFQESPELNNTCTCFFTIGIEPWRTRFDLWNKTCSGGHS
What are the official names of this protein?
Putative cystatin-9-like protein CST9LP1, Cystatin-9-like pseudogene 1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FA8_HUMAN
Sequence: MQIELSTCFFLCLLRFCFSATRRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFNTSVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGDYYEDSYEDISAYLLSKNNAIEPRSFSQNSRHPSTRQKQFNATTIPENDIEKTDPWFAHRTPMPKIQNVSSSDLLMLLRQSPTPHGLSLSDLQEAKYETFSDDPSPGAIDSNNSLSEMTHFRPQLHHSGDMVFTPESGLQLRLNEKLGTTAATELKKLDFKVSSTSNNLISTIPSDNLAAGTDNTSSLGPPSMPVHYDSQLDTTLFGKKSSPLTESGGPLSLSEENNDSKLLESGLMNSQESSWGKNVSSTESGRLFKGKRAHGPALLTKDNALFKVSISLLKTNKTSNNSATNRKTHIDGPSLLIENSPSVWQNILESDTEFKKVTPLIHDRMLMDKNATALRLNHMSNKTTSSKNMEMVQQKKEGPIPPDAQNPDMSFFKMLFLPESARWIQRTHGKNSLNSGQGPSPKQLVSLGPEKSVEGQNFLSEKNKVVVGKGEFTKDVGLKEMVFPSSRNLFLTNLDNLHENNTHNQEKKIQEEIEKKETLIQENVVLPQIHTVTGTKNFMKNLFLLSTRQNVEGSYDGAYAPVLQDFRSLNDSTNRTKKHTAHFSKKGEEENLEGLGNQTKQIVEKYACTTRISPNTSQQNFVTQRSKRALKQFRLPLEETELEKRIIVDDTSTQWSKNMKHLTPSTLTQIDYNEKEKGAITQSPLSDCLTRSHSIPQANRSPLPIAKVSSFPSIRPIYLTRVLFQDNSSHLPAASYRKKDSGVQESSHFLQGAKKNNLSLAILTLEMTGDQREVGSLGTSATNSVTYKKVENTVLPKPDLPKTSGKVELLPKVHIYQKDLFPTETSNGSPGHLDLVEGSLLQGTEGAIKWNEANRPGKVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKKDTILSLNACESNHAIAAINEGQNKPEIEVTWAKQGRTERLCSQNPPVLKRHQREITRTTLQSDQEEIDYDDTISVEMKKEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYGMSSSPHVLRNRAQSGSVPQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKEPFSWIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY
What is the function of this protein?
Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
What are the official names of this protein?
Coagulation factor VIII, Antihemophilic factor, AHF, Procoagulant component.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: F16PC_STRA1
Sequence: MSNFYKLLKEKFPRKEDIVTEMINLEAICQLPKGTEYFISDLHGEYDAVDYLLRTGAGSIRAKLLDCFDWQKIVAVDLDDFCILLYYPKEKLAFDKMNLSASAYKTKLWEMIPLQIQVLKYFSSKYTKSKVRKQLSGKFAYIIEELLAEIDRNPEKKSYFDTIIEKLFELDQVEDLIIVLSQTIQVLIIDHLHVVGDIYDRGRYPDRILNRLMAFPNLDIQWGNHDVTWMGAASGSYLCMVNVIRIAARYNNITLIEDRYGINLRRLVDYSRRYYEPLPSFVPILDGEEMTHPDELDLLNMIQQATAILQFKLEAQLIDRRPEFQMHNRQLINQVNYKDLSISIKEVVHQLKDFNSRCIDSKNPSRLTSEEEELLQQLMIAFQTSESLKKHIDFLFEKGSMYLTYNDNLLFHGCIPMHSNGDFKSFKIAGKTYGGRDLLDLFESQIRLAYARPEKHDDLATDIIWYLWCGENSSLFGKNAMTTFERYYVSDKVTHQERKNPYFKLRDKDDICTALLQEFDLPKFGHIVNGHTPVKEKNGEQPIKANGKMLVIDGGFAKGYQKNTGLAGYTLIYNSYGIQLISHLPFTSIEEVLSGTNYIIDTKRLVEEAKDRILVKDTTIGQKLTKEIKDLDHLYRHFQEYDD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: SDC1_BOVIN
Sequence: MRRAALWLWLCALALRLQPALLHSVAVNMPPEDQDGSGDDSDNFSGSGAGALPDITSSHTPSTWKDLGPVTTTATAPEPTSPDAIAASTTILPTGEQPEGGRAVLLAEVEPGLTAQKEATHPPSETTLHPTTHSVSTARATMAPGPATSHPHRDVQPDHHETSAPTGRGRMEPHRPHVEEGGPPATEKAAEEDPSTQIPVGEGSGEQDFTFDLSGENAAGAAGEPGSRNGAPEDPEATGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
What is the function of this protein?
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.  Regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
What are the official names of this protein?
Syndecan-1, SYND1.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted. Secreted, extracellular exosome. Note=Shedding of the ectodomain produces a soluble form.
Protein: ERPA_METFK
Sequence: MNAVTEEIPSPLIFTDNAARKVKELIDEEGSPDLKLRVFVSGGGCSGFQYGFTFEETINEDDTTVDKDGVTLLIDPMSLQYLVGAEIDYQDSLQGSQFVIRNPNATTTCGCGSSFSA
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RS3_SYNJA
Sequence: MGQKIHPTGFRLGVIKEHRSRWFADPARYPALLREDDLIRAYLTKQLSSAGLADIQIERKADQIDLEIRAARPGVVVGRGGSGLDALRQGLQKELSSHGSPERTIRINVVEVTRADAEAVLLAENIAQQLERRIAFRRIVRQVIQRAQRAGVQGIKIQIAGRLNGAEIARTEWTREGRIPLHTLRADIDYADHIAQTTFGVIGVKVWVFKGEVLPGQERPEQKVPLQQPKRRQQRRRPTFEDRSAVEA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HBB_BRACA
Sequence: VHWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFSSFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFAKDFTPDCQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL40_SULIY
Sequence: MPLTDPAKLQIVQQRVFLKKVCRKCGALNPIRATKCRRCHSTNLRLKKKELPTKKG
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: PYRH_ORITB
Sequence: MNNLRYNRLLIKLSGAALKGDSNTDNFDIKKLKYIAQEILAIKNMGIEVVLVTGGGNIFRGNSAEYWKIERAEADNVGMLGTIINALMLKAALEKESNYKVRVMSAIKIEAVAEPFIRSRALSHLYKGYLIILAAGIGQPFITTDYTAAQRALELRCDAMLVAKHGVNGVFDSNPKEDTNARQYCTLAYDDFLINQLNIMDHSAVLLAKQHNLPIHIFNFDQELAAKNICLGKNIGTYISSNTKMQFSN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP2_CORJK
Sequence: MSEMQMPEMRYILPSFVEHSSYGAKESNPYNKLFEERIIFLGTQVDDASANDIMAQLLVLEGLDPDRDITMYINSPGGSFTSLMAIYDTMQYVRPDVQTVCLGQAASAAAVLLAAGTPGKRAALPNARVLIHQPATGGVQGQVSDLEIQAKEIERMRKLMEETLARHTGKSAEQVRIDTDRDKILTAEEAKEYGIVDQVFDYRKLSAQN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_CERS5
Sequence: MPAIESGLLALILTGVLGYLLGSIPFGIVITRAFGLGDLRRIGSGNIGATNVLRTGNRPAALATLLLDSGKGAIAVLIARAAVGEDAAQLAAFTSFLGHLYPVWLGFRGGKGVATFLGTLIALAWPVGLACCLTWLATAAVSRISSLSALMAAASGVVWMLLLGQGQMAALGLVLAVLIFIRHHENIRRIANGTEPRIGKKASQDQSAEQ
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD_PYRFU
Sequence: MNILIFGPPGSGKSTQARRIVERYGLTYISSGDLIRKEIAEGTPLGREMQAYLARGDLIPDTIVNTLIISKLRRVRKDFIMDGYPRTPEQVIALENYLYDHGIKIDVAIDIYVSLEESIRRVSGRRICPKCGAVYHVEFNPPKIPGRCDVCGAELVQREDDRPEVVEKRYRIYMKNMEPIIKFYQKQRIYVKINGHGNIDEVWERIRPLLDYIRNREAMI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.