PharMolix/UniProtQA huggingface dataset:
Protein: PSBA_CUSOB
Sequence: MTVVLDRRKSENLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFLIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASIAEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAIAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTESESANKGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISTMAFNLNGFNFNQSVVDSKGHVINTWADIINRANLGMEVMHERNAHNFPLDLATFEVSATNA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: YIPF5_XENTR
Sequence: MSNFDNFNTDFYQTSYSIDDQSQGYNYNAGGAQHSKQYAYDPYSQQGGFIPPEMMNQQQPYTGQIYQPTQTYTPAATDSVYGSTFDDEPPLLEELGINFDHIWQKTLTVLHPLKVADGNIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMYCLLNLMSMTGVSFGCVSSVLGYCLLPMIILSSFAVIFSLQGILGIVLAALIIGWCSFSASKIFISALAMDGQQVLVAYPCALLYGVFALISVF
What is the function of this protein?
Plays a role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Protein YIPF5, YIP1 family member 5.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: CCMH_PSEFL
Sequence: MKRLLAAAVCLGPGRCGHAAIDTYEFANDAERERFRDLTKELRCPKCQNQDIADSNAPIATDLRREIFRMLGEGKDDQQIIDFMVDRYGDFVRYKPALTGKTALLWFGPAGLLLAGVVVMAVIVRRRRAAPTDGSDALSPEERKRLDQLLDTKTDD
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmH, Cytochrome c-type biogenesis protein CycL.
What is the protein family that this protein belongs to?
Belongs to the CcmH/CycL/Ccl2/NrfF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein; Periplasmic side.
Protein: TEG5_EHV1V
Sequence: MDQHHGARGGAPIRRPRRSIESRSHPFRATGNTQRTYSTPRLSYRDGLSGRTASRDPQEQASNQDESSNPSTSNAQQSTSFWGYLRRVFSDDVPAQPQAPRPRADFAPPAGEESSSEEEEEEGPAQAPLDEEDQLMYADQYSVGDSSDENDEEEDPRLGSDYPTSAESSEYHDHGEMVAGAGAESESETDIDAEEEEEDDEDDEDDMEVIRDESYRLPRTWLDKSIRLMDEALAQSSELSKAITKSTRSLYDSQFAPGGRGYTQTATPSRRLVQLSRAGMYDSDKIVMTGDYMEVDDDPDSAYQLWVRAIRHPLAMNPSWEETISNHTNPSFSTDIDYDIDELIEKNLARTPPVFEGLLDSAEFFYKLPMLYTYATITQDEAYEERLAWSNTQALHGHEQSSWQALLVYYSRGGMYVSPTQEPRGIWRRALKQAMALQLKMCVLGLSDVVTKQNATHHHTAVTFLVDALLRTARNCYLASRLLVFAWERRRETGAKRPAEPLIALSGVTLLQPLPPEVSELLEQRTFDIGLRTPNSAVFRAFFGSLVYWAELRLALRDPASINCRYVGFHLQTSEIYLLARAHSASPGYTKEELVAMEAILTLATLMLEVALQWVHVACAQLLSENDTIKAFRRVSASIPHALAPLGSIRLHDAEFEVLSNPDVMVARDETALSQALFLGYFSVRTALTACMRDYSHEADGGSKETVTGVFLGVGLILQRLAGHLNFLLNCLAGAALYGGQKINIHSLTLPRYSLLADVMAPMLQRQSLVDFWRARDNMLEDLEITPRPGPPTQGKRVVVEMPLPSDDLPDMTPGASVNNGAGLGRMVDMAKQLQHYRETIIGEEATSSVGKRGLIRAGVGVAALRGRRRK
What is the function of this protein?
Tegument protein that can bind to various RNA transcripts.  Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase UL41/VHS.  Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins UL31 and UL34.
What are the official names of this protein?
Tegument protein UL47 homolog, GP10.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL47 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection. Localizes to the major sites of transcription in the infected cell nucleus.
Protein: HIS8_LACPL
Sequence: MKASIEQLEPYVPEKPLATLQAELGLTELVRLSANENPYGTSPKVATAVKNWDFTQSNRYPDADAQELRQAVAQQQGIDPNSIVFSVGLDEMIVMLSRTFLATNDQVLVSAPTFSEYGLHAEIEGGQLISVPTLPNDHVNFEGLMKAITPHVKMVWLCNPNNPTGTVESLAAIEAFVQQVPPETMVLIDEAYIDFTPGAAQVTAMQLPAKYPNVVVMRTFSKAYGLANFRIGYAVFNTKYAATMQTIRLPYNVNSLAQVAALAAIDDPNFVKQTVQKNATERAKWMAFFDDQGVTYDQSGANFIFFKYPSATQLADYLVHHGYLIRTGLRPGWLRLTVGTANDNQQLQQLIREFKA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL24_STAHJ
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATEPKKDRVVVEGVNVIKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIVKKSGEEIKTNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: OBG_SALDC
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRDLLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDSEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGSDPVENARIIIGELEKYSQDLAAKPRWLVFNKIDLMDKTEAEEKAKAIAEALGWEGKYYLISAASQLGVKDLCWDVMTFIIENPIAQAEEAKQPEKVEFMWDDYHRQQLAEVEEDADDDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS1B_ASPNG
Sequence: MAANGSSSEGDHRLLIVSNRLPITIRRSGGGKYEFSMSSGGLVTGLSGLSKTTTFQWYGWPGLEVPEDEIDSVKQRLQEEFNATPVFMDDKLADRHYNGFSNSILWPLLHYHPGEIVFDEAAWDAYREANRLFAKTIAHEAREGDLVWVHDYHLMLLPEVLREELAALGKNNIRIGFFLHTPFPSSEIYRILPVRSQLLRGVLQCDLIGFHTYDYARHFLSCCSHILGLVTTPSSVKFKDRSVAVGAFPIGIDPDKFTEGLKSPKVQNRIASLENKFQGTKLMVSVDRLDYIKGIPQKLHALEVFLSQHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVDYMPIHFMHKSVSFDELIALYAASDACVVSSTRDGMNLVSFEYVATQQKRKGVLILSEFAGAAQSLNGSIVVNPWNTEELASAYHEAVSMSDDLRAQKFEKLYKYISKYTSAFWGKSFVAELSKCST
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2, Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: SYS_SULTO
Sequence: MSWSILELVRNNPDKLKEYIKRRFIDVSLVDRAVELDKKWRQTLQEVEKLRHEHNVISSSIPKAKPEERQELIKKAKELLKALEEKEKELDNIENERDNILMQLPNIVDDSAPIGPDETYSVPIRFWGKFKVYEKDEAEFLSQLKGNRVDYEIIHWKPVGHADMLENVLKLGDTKKAAEVSGARFYYLFDDIVWLDIALLNYAIDTMTSKGYTLVLPPYMLRGEVIKSVIDLDTFKDAIYKIENEDLYLIATAEHPIAALYFKEEIPKEKLPLKYVGISPAFRKEAGAANKDLKGIFRVHQFHKVEQFIFSSPEDSWKLHEELIRNAEEIFQGLGLPYRVINIATGDLGACAAKKYDLEVWMPAQAKFREMVSCSNCLDWQAYRMRIRYVEKGGKKGYVHTLNSTAIASTRTITAILENYQREDGVVEIPKVLKKYLEPFSRAPKDYIYPRKE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_MYCBO
Sequence: MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: VGLL4_MOUSE
Sequence: MLFMKMDLLNYQYLDKMNNNIGVLCYEGEASLRGEPRMQTLPVASALSSHRTGPPPISPSKRKFSMEPGDKDLDCENDHVSKMSRIFSPHLNKTVNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSLMEQPLALTKNSSDTGRSAVERQQNRPSVITCASAGARNCNLSHCPIAHSGCSAPGSASYRRPPSATATCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDSASSSPESASRRGQPASPTAHMVSHSHSPSVVS
What is the function of this protein?
May act as a specific coactivator for the mammalian TEFs.
What are the official names of this protein?
Transcription cofactor vestigial-like protein 4, Vgl-4.
What is the protein family that this protein belongs to?
Belongs to the vestigial family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCSE2_MOUSE
Sequence: MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMPNGATVTLLGTSKSSNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQSTHDKLIEPEQHAPAPGTLDGHGIKGGLKSASLFTSKLARPSTMFVSSAEELSQKSFSGPSNLGKFTKGTLLGRTSYSSVNAKSHLNAFYGNRSSGNVQKPRVNSCASRSSSGESLAQSPDNAKSITCEKMVRSQSFSHSIQNVFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLRSGMLTRSSLQSEVLNGNEHVGFGFNRPYAAAGKKLALSNGPAVSSTLVYRMAHPPLLKSSRPPFSGPMTVDSNKNPPADMCVEEEGMVSAQDSSPGKDQELIENESYRRDNDQTGKNESKVRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITPEEMTLKEEKHESRPSKDIFDSPKESEQAFSKAEEWIDISVSDRSECTKHTSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGSVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRTDRNVRQSQDGFWKRPPQRWSGQDHYHLSHPGHYHHHGQSDLSRGSPYRESPLGHFESYGGTPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLSLPSSPEPEDGDQIYKNEDLLNEITQLKEEIKKKDEKIQLLEQQLATRCNCQQKSKEEKCTYADKYTQTPWRRIPGGYCAPSFSPWQGSFQGMPRTVPPHRRQTSSTTAFQQPSQIYRPRPGKTNKATTYRGPQ
What is the function of this protein?
Microtubule-binding protein which might play a role in microtubule bundling.
What are the official names of this protein?
Serine-rich coiled-coil domain-containing protein 2, Coiled-coil serine-rich protein 2, Granule cell antiserum positive protein 14, Protein GCAP14.
What is the protein family that this protein belongs to?
Belongs to the CCSER family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with microtubules in interphase. Has diffuse expression throughout the cell during mitosis.
Protein: Y547_RICPR
Sequence: MSRVYKIKNLEEARNFLYSIEEPLILTNDDSSIKYYGMLVIDYMFKTLRREFPEKVLALTVNVGQDHAALFTAIKLGYKNIVYIGASAEAKRLLSDLYNNPITYKV
What are the official names of this protein?
Uncharacterized protein RP547.
Protein: Y2910_MYCTO
Sequence: MCAVLDRSMLSVAEISDRLEIQQLLVDYSSAIDQRRFDDLDRVFTPDAYIDYRALGGIDGRYPKIKQWLSQVLGNFPVYAHMLGNFSVRVDGDTASSRVICFNPMVFAGDRQQVLFCGLWYDDDFVRTPDGWRIIRRVETKCFQKMM
What are the official names of this protein?
Uncharacterized protein MT2978.
Protein: RL7_SYNP6
Sequence: MSAKTDEILESLKTLTLLEAAELVKQIEEAFGVSAAAPVGGVVVAAAAGAAAEAVEEKTEFDVVLEEVPADKKIAVLKVVRGITGLGLKEAKDLVEAAPKPIKEGVSKDDAEAAKKELEEAGAKVSVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y152_MYCTA
Sequence: MSSLPSSRRTAGDTWAITESVGATALGVAAARAVETAATNPLIRDEFAKVLVSSAGTAWARLADADLAWLDGDQLGRRVHRVACDYQAVRTHFFDEYFGAAVDAGVRQVVILAAGLDARAYRLNWPAGTVVYEIDQPSVLEYKAGILQSHGAVPTARRHAVAVDLRDDWPAALIAAGFDGTQPTAWLAEGLLPYLPGDAADRLFDMVTALSAPGSQVAVEAFTMNTKGNTQRWNRMRERLGLDIDVQALTYHEPDRSDAAQWLATHGWQVHSVSNREEMARLGRAIPQDLVDETVRTTLLRGRLVTPAQPA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MRA_0152.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: ACPXL_AGRFC
Sequence: MGVTATFDKVADIIAETSEIDRETITPESHTIDDLGIDSLDFLDIVFAIDKEFGIKIPLEQWTQEVNEGKVSTEEYFVLKNLCAKIDELRAAKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.  Is involved in the transfer of long hydroxylated fatty acids to lipid A (By similarity).
What are the official names of this protein?
Acyl carrier protein AcpXL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_DECAR
Sequence: MPGFSRRPLAVFVCCLFAGVQTGHAAADIERAMVQGESTAPAAERSVAMQLAAVSELPLNLRKERKFDVLGKKKQPAEPVAPMLAPEKPIELKKDDAYPLFIVADQIEGQADELTEAEGDVELRKVGTLIYADRLTYRPLEDEVEATGSVRMLQDGAEISGPHMRMKLADQIGSAEQVTYHIVKEVPSRFYAPQQTVVTVASSNATNSGAPMMLNVSNSYGLPTQLPPPRPSEANGYAERVEFEGENQMTLFSNTYSTCKPGQADWYMKSSETHLDYDRSEGTARNATLWFGGVPIVYTPVAGFPLSTQRRSGILHPHFSASTRSGLDISVPYYLNLAPNYDLTLVPRYMSKRGMQLGADARYVDYFYEGEARFEYLPNDEMLGRSRYGYRFEHRHNLGQGVSAALNWNGVSDDLYWQDLSSRLLQTSQAQLPRQVSLGYSPSPWLQSNLQVLRYQTLQIDPNNPVTRPYFLEPQLNLVGYKPNIWKTDFSMVGQFSRFTHVDAGKVQGDRMVFYPQLSLPIVHPAFQITPKIGLHMTKYTLDQQAAGLPESISRVLPTFSLDSTVILEREGDWFGRGYIQTLEPRLYYVNIPYKDQSQIPLFDSGLSDFNFAQIFSENRYSGYDRINDANQLTAALTTRLLDGETGVERLKAMVGQRYYFKPQRVAITGETTRQNDFSNLVAAVNGLVAPKTYADVAWEYNYRENISERFSAGVRFQPELGKVMSASYRYTRDPLTTLSTVDQVDIAGQWPISANWYAVGRYNYSLRDKRVLESIAGVEYNAGCWAVRLVGQHLGAISGAANDTVFFQLELNDFGSIGSNPIGLLRRSIPGYGKINELPTSSSLLTSQ
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PEPT_ALIF1
Sequence: MKDLVERFLSYVSIDTQSNPSAPQCPSTEKQFNLANQLVSELNELELSDVSIDENGYVMGRLPSNVDYDVPAIGFIAHMDTAPDASGENVKPQIINNYQGDIITLGTSGEELTPSQFPDLLNLIGHDLITTDGTTLLGADNKAGIAEILTAIAVLKANPEIPHGDICVGFTPDEEIGRGANLFDVKKFNAKWAYTIDGGPVGELEYENFNATSADVICHGVNVHPGTAKGKMVNSMNIAAQFQMMMPADETPEGTEGYEGFYHLKSMNAGVAKTELGYIVRDFSREGMAERKAFMQQKVNELNAKLEKGRVELVLTDSYFNMREMVEPHPHVIELAKEAMTACDIQPDIKPIRGGTDGARLSFMGLPCPNIFTGGYNFHGIHEFITINGMKQAVDVIVKIAELNASNNK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACLG_ASPOR
Sequence: MEYDGRVILYIIKADETSYINYIKPLILAEEIQFPHVLSVIDTRDEWFYSIHPERMVPSLKDQDPVTGEKVIVFESTACLQYLVDRFDTDGTWSGRTVAEKGAVLSWTAYQTAALGPTAKYWLYFKRGYPTRANPVQLPRTIEKQWDILEKRLKEPGQQYIALKDRPTLADLSYFPFAMPWMFTFLGVDIKDWPHIQRWSERMLSRPAVARVLQRAPTLGH
What is the function of this protein?
Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Glutathione S-transferase aclG, Aspirochlorine biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: BGL18_ORYSJ
Sequence: MAGGSKTRIHASLVSTLLLLLPLASAIHRSDFPASFLFGTATSSYQIEGAYLEGNKSLSNWDVFTHLPGNIKDGSNGDIADDHYHRYEEDVELMNSLGVNAYRFSISWSRILPKGRFGGVNPAGIDFYNKLIDSILLKGIQPFVTLTHYDIPQELEDRYGAWLNAEIQSDFGHFADVCFGAFGDRVKYWTTFNEPNVAVRHGYMLGTYPPSRCSPPFGHCARGGDSHAEPYVAAHNVILSHATAIEIYKRKYQSKQRGMIGMVLYSTWYEPLRDVPEDRLATERALAFETPWFLDPLVYGDYPPEMRQILGGRLPSFSPEDRRKLRYKLDFIGVNHYTTLYARDCMFSDCPQGQETQHALAAVTGESNGLPIGTPTAMPTFYVVPDGIEKMVKYFMRRYNNLPMFITENGYAQGGDSYTDAEDWIDDEDRIEYLEGYLTKLAKVIRDGADVRGYFAWSVVDNFEWLFGYTLRFGLYYIDYRTQERSPKLSALWYKEFLQNLHENQ
What is the function of this protein?
Hydrolyzes glycosides and monolignol glucosides (PubMed:25219312).  Can hydrolyze para-nitrophenyl beta-D-glucopyranoside (pNPGlc) in vitro (PubMed:23811195, PubMed:25219312).  Hydrolyzes para-nitrophenyl beta-D-fucopyranoside, para-nitrophenyl beta-D-galactopyranoside and para-nitrophenyl beta-D-xylopyranoside in vitro (PubMed:25219312).  Hydrolyzes the monolignol glucosides coniferin and syringin with high catalytic efficiencies (PubMed:25219312).
What are the official names of this protein?
Beta-glucosidase 18, Os4bglu18.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: DNCH_SYNP6
Sequence: MADYQFQRVIRFGDTDAAGVVYFAQLLSICHEAYEAAIAALGIELRSFFSDRGSVILPIVHAEIDYQRPTYCGDRLEIELQATALGRDRFRVDYRLSHNHQPVATAQTIHLCLESQTRQRSPLPERLQDWLQITAD
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: TPP9_ORYSJ
Sequence: MTKHGAVVVPEDAVVAAAAVGRHFSFPPPRTGGVGGDSCKKLAAQQIDLGAAVIGSWLDSMKASSPRHRLVAPAVAAAAADAEHDEWMEKHPSALGKFEALAAAAKGKRIVVFLDYDGTLSPIVEDPDRAVMTDEMRDAVRGVAARFPTAIVSGRCRDKVLSFVGLEELYYAGSHGMDIQGPTNAAASKGGEEEEESVLCQPAREFLPMIGEAYAALVEKVEGVIPGAKVENNKFCLSVHFRRVDERRWGAVADQVRAVLRGYPRLRLTQGRKVLEVRPAIKWDKGEALRFLLSALGFSAAGDVEDDGDDDDAFPIYIGDDRTDEDAFRVLRARGHGAGILVSRFPKDTCASFSLRDPGEVKDFLRKLVTCAAA
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Trehalose accumulation in plant may improve abiotic stress tolerance (By similarity).
What are the official names of this protein?
Probable trehalose-phosphate phosphatase 9, OsTPP9, Trehalose 6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: PETG_FAGEA
Sequence: MIEVLLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PPIE_MOUSE
Sequence: MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGPEPPKAEAQEGEPTAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQGSKDGKPKQKVMIADCGEYM
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Combines RNA-binding and PPIase activities.  Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules.  Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.  Inhibits KMT2A activity; this requires proline isomerase activity.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophilin E, Cyclophilin-33, Rotamase E.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LNAA_ASPFN
Sequence: MPSQVLTHEEEYDLAVRQGKGLAQQFFDHAFLNPSAMAVIDGDTNLTYQDLHERAAMLARELQRGNLHTEEPVGVVVQHGISDVVAQMAILYAAGTCVPMDPTLPDLQIKGRLDRLKARYILVDRANQHRDLPFHPLIVDDSSASFSKSSHVRDNEEPMQITLEHRTHIIHTSGTTSEPKAVQIAARSILQVVFHAPFEPLYPTDRVAHVNNSSFDVSLFDIWAPLLRGACIVVVSKVTLLDLETLAAYIDRQGITVMATTTAILNLAASVYPRAFEKLRLCFIGGEAANISAIETIFQAGPPTQLINAYGPTECCIFCLAHRVTIADVQAGVVSIGKPIGRTVAYICDEAGRPVPDGHEGELLIGGAGVSPGYINQPDKNRASFVAIEGSDCQRFYRTGDIVRRRVSNGQIDYVGRRDHQVKVRGFRIELEAVESAIMKTGQFSEAVALKVEAGSEGAGSILVAFAVALSGTKPHAVLSAVDMLKAVLPDYMVPKIELISKMPVNSHAKVDRKYLQQLFRNRWAEQHIDMDNEDSTRGKLANLWASILGVPVPASNDNADFFLLGATSMQASLLISRIQKTFNVQVSLLTLYDNSSLIRLAGILEERILGTQESFCKESERHMWLEDSKLADSLVPPSDPPVDWCRDTEGRVFLTGATGFVGSFLLADLLRQPNVHQVGCLVRAVDPATGLRRLQNGLAKYDLWEDQFRYKLLPLCGTLEDRYLGLGPDRFEEIAHWASVIFHLGARVNYTQPYSLHRPANVQGTVNVLRLACAGRSKVLHYVSSISCFGPTGFITGTRTVMENEPLPRHLEALPYDHGYAQSQWVVENMLQRLMDNGFPIVVYRPGFITGHSQTGACNPDDFLSRLIIACGEMGSYPLLPNQRKEFVPVDYVNAVILHIASSTATAVGRVYHIVPPNRDLSLDMNDSMELVGSLAEGNESSVRGVSYQQWVQELDRQSPERLRPLQPMLTEKLYQGLTRWELYENMPVYDTTNTRQALESYPGGLKFPVLDSELMQKYIRYLQIRSASPKEENPLNGTDS
What is the function of this protein?
Non-canonical nonribosomal peptide synthetase; part of the lna gene cluster that mediates the biosynthesis of diastereomeric piperazines.  Lna and lnb clusters encode sets of enzymes that produce overlapping sets of previously undescribed metabolites such as piperazinomycin-like metabolites or morpholine (PubMed:23281040).  The lna and lnb biosynthetic pathways appear to be part of a signaling network that controls the formation of sclerotia, a resilient overwintering structure (PubMed:23281040).  One primary function of the non-canonical nonribosomal peptide synthetases lnaA and lnbA consists in the reduction of L-tyrosine (PubMed:23281040).  The presence in the clusters of tailoring enzymes such as the oxidoreductases lnaB, lnbB, lnaE or lnbE, as well as of the cytochrome P450 monooxygenases lnaC, lnaD, or lnbC, might explain formation of various diastereomeric piperazines (PubMed:23281040).
What are the official names of this protein?
Aldehyde reductase lnaA, Lna diastereomeric piperazines biosynthesis cluster protein A, Non-canonical nonribosomal peptide synthetase lnaA.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.