PharMolix/UniProtQA huggingface dataset:
Protein: NPP_HORVU
Sequence: AAVRASPDLLGSRGEDTASDGSVVWAKPYTFRAPPTPGQNSLQRIIVFGDMGKAERDGSNEFANYQPGSLNTTDRLIEDLDNYDIVFHIGDMPYANGYLSQWDQFTAQVAPISAKKPYMVASGNHERDWPNTGGFFDVKDSGGECGVPAETMYYYPAENRANFWYKVDYGMFRFCVGDSEHDWREGTPQYKFIEECLSTVDRKHQPWLIFTAHRVLGYSSNSWYADQGSFEEPEGRESLQKLWQRYRVDIAYFGHVHNYERTCPLYQSQCVNADKTHYSGTMNGTIFVVAGGGGSHLSSYTTAIPKWSIFRDHDYGFTKLTAFNHSSLLFEYMKSSDGKVYDSFTIHRDYRDVLSCVHDSCFPTTLAS
What is the function of this protein?
Hydrolyzes pyrophosphate, phosphodiester and phosphosulfate linkages of nucleotide-sugars, sulfonucleotides and nucleoside di and triphosphates.  Highest activity observed with the substrates ADP-glucose and adenosine 5'-phosphosulfate.
What are the official names of this protein?
Nucleotide pyrophosphatase/phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VPR_SIVML
Sequence: MEERPLENEGPQREPWDEWVVEVLEELKEEALKHFDPRLLTALGNHIYNRHGDTLEGAGELIRILQRALFMHFRGGCNHSRIGQTWGRKSSLNYTALLRRAITHAIVKSVATIASFVFLKRD
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PACC_MAGO7
Sequence: MSAQQPSAQPAQQAPATTQAPTTESSSSNSNGNTPAPSTSTTATSQSSDDSLICRWNQCSERFPSAEALYDHICERHVGRKSTNNLNLTCHWNSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKSFKRPQDLKKHVKTHADDSVLARSPQDPNANLGPGAYRGHASKAPSSYYDHNGHVRTNSSAFGQPHHHQNGHASYYSHPPAPYGGGMYYQPPHMGPRGDIFGHPGAGAYDSRKRGYDDLNDFFGNLKRRQFDASSYAHVGRSLVPLHGALSVHTGGVGGMAAEYMAAPPPSSSVSMGSAGPLAQHYYLPPMPSLRTKNDLEQIDQILEHMQSTVYENSGSSPGAHYGSGSGYDMRHQSPVGIRPPMSDHYGQQQHSPMTAVSSSHGGSPAVTPPSSNLSYTSGHSPGASSAALSPSSRQGSSISYPTLPAAAGSSATAQLGSNFSSVERRLSGGILQSASRDRERESSYDGASTPRGPESVGSPSACSDASGSEPESYDSWVQNMRTIEALRDLVRERLRRGQYDDVEESVNLPPIKTERPDEEKPLYPSLRMS
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPI_RANMC
Sequence: MNVLPCSVNTLKGLYDISGVEVGQHFYWQIGGFQVHAQVLITSWFVIAILLGSAIIAVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALPTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATPA_ECO24
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TDA11_LACTC
Sequence: MSKLDGFIEEHDRESNIDSGARLESTKPSPKVGSPAQRVRQNGVKSPILQTQATPAKPSEQEHPLKETPTRATAGGKMTRSNTLKRLSLIQPVISPETTPKEHRQQQATRNRSRSVVSVHSRSSSSASEQLADATKDVNALLQLLANKELELLETKHKIEELKKTLTQEEKALLRQTHELQDLKTQVGKALNSGIDEQIQQQSQSSHHSPNQRSLAVPTSHTPGNESRPAHAKKESVWTKPLSFLNQFDQLIQHELEKKLNWDDVASPEKTPGAESGTLSGRSASPASYNNGNSNNNNNNNSNRGRPNEDVLGNMSSSLWSFVSDVKTGLLGINEEEEEESAEAPAVASSGESNNQLRFVGSKNNSEVELKEYNASKRQ
What are the official names of this protein?
Topoisomerase I damage affected protein 11.
What is the protein family that this protein belongs to?
Belongs to the TDA11 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_STRCO
Sequence: MSGFVEKPEPIQVPGLVHLHTGKVRELYRNEAGDLVMVASDRISAYDWVLPTEIPDKGRVLTQLSLWWFDQLADLAPNHVLSTELPPGAPADWEGRALVCKSLRMVPVECVARGYLTGSGLAEYDETRTVCGLALPEGLVDGSELPAPIFTPATKAEVGEHDENVSYEEVARQVGADTAAALRQATLAVYSRARDIARERGIVLADTKFEFGFDGDDLVLADEVLTPDSSRFWPADRWQPGRAQPSYDKQFVRDWLTSAESGWDRKSEQPPPPLPQQVVDATRAKYVEAYELLTGQSWS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PHS_CYAP4
Sequence: MAQLLSDIEINSQIGQLPDWSVVGQEIQMVRKFKDFIAAIDFVNKLVEPAEAAGHHPDIAISYNKVTITLTTHDAGGLTQKDFDLAQVISQLSRIWV
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: SBMC_ECOLI
Sequence: MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.  Protects cells against the natural plasmid-encoded toxins microcin B17 (MccB17) and CcdB, and synthetic quinolones.  Can also protect cells against alkylating agents that act independently of DNA gyrase, suggesting a more general role in protecting cells against DNA damage.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_BURMS
Sequence: MRVAQVVRNTSETQISVKIDLDGTGRQKLATGVPFLDHMLDQIARHGLVDLDIEAHGDTHIDDHHTVEDVGITLGQAVAKAVGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQLETVFKAFGRALRMAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YADH_ECOLI
Sequence: MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGNLIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPTHVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLNGVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGFLGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS
What are the official names of this protein?
Inner membrane transport permease YadH.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP_BARHE
Sequence: MSDTVERVKKIIVEHLGVNADKVVEDASFIDDLGADSLDTVELVMAFEEEFGVEIPDEAAETIFTVGDAVKFIDKASA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_SALPA
Sequence: MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CCME_HALHL
Sequence: MKKRHQRLFLVLGVVAGVSVATALVLNAFRDNMTFFITPSEVMAKSDMPERHFRIGGLVEDGSVERDSDSTQVRFRVTDTEASVPVDFEGILPDLFREGQGVVVEGRITSNGVFKADNVMARHDEDYMPAEAQEALDRVEHSVDEVGDY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: BTUD_ECOBW
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PDXH_NOCFA
Sequence: MAADLAAMRVDYGGVPSGSGEDVDLDEAWLAGGWEPLLRNWIEQATAVDIAEPNAMVLATVAVVDGVPRPASRTVLCKGLSPEGVTFYTNYDSAKGTQLAAVPYAAATFVWPVLGRQVHLRGPVERTSAEQTAVYWRSRPRDSQLGAWASQQSRPIDSRAALDRALAEVTARFAGVDEIPVPPHWGGYLLRPEQVEFWQGRRGRLHNRLLVRVAGERMTVERLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ACTH_RAT
Sequence: MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1747_PSEPK
Sequence: MLIPYDQLQAETLTRLIEDFVTRDGTDNGDDTPLETRVLRVRQALAKGQAFILFDLESQQCQLLAKHDVPRELLE
What are the official names of this protein?
UPF0270 protein PP_1747.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: GMHA_SHIDS
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGCEGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMADTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_RHIME
Sequence: MKRTYQPSKLVRKRRHGFRARMSTKGGRKVLTARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: YIDD_CHLAD
Sequence: MLRWLLLKLIRFYQVAISPWTPPSCIYTPTCSHYGYEAIQKYGALRGGWMTIKRIARCHPFARGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNLJ_PSEA6
Sequence: MSNALSPAQRLTQIINTINEYNYQYYVQDNPSVPDAEYDRLMRELLDIENNHPDLRSPDSPSQKVGGAALSAFEQVEHEVPMLSLDNAFDEDDMQAFEKRIKDRLKISSEISFSCEPKLDGLAVSILYENGQLVRAATRGDGRVGENITTNVRTIANVPLRLRGENFPSRLEVRGEVIMTRAGFVTLNEAQIKKGKKPFVNPRNAAAGSLRQLDPKITAARPLLFYSYSLGLVENEQQPLGETHSSRLAQLSEWGLPLSKELEVTQGATQCLTYFHKIGELRSQLSYDIDGVVFKVDNIAMQQELGFVARAPRWAIAHKFPAQEEMSTLLDVEFQVGRTGAITPVARLEPTFVGGVTVSNATLHNQDEINRLGIKIGDSVIIRRAGDVIPQIVAIVADKRPDDAKDIVFPESCPVCDSAIEKLEGEAVARCTGGLYCKAQRKEAMKHFASRKALDVDGLGDKLIEQLVDAEMVKSPADFFALDIAPLSSMERMGEKSAVNLVNALEKSKKTTLAKFLYSLGIREVGEATAQNLAQHFLTLEAIEQADLDALQAVSDVGVIVAQHVFNFFKEEHNLEVISALLEAGVHWPKIEKLALDELPLAGQVYVLTGTLNVMDRNSAKAKLQSLGAKVSGSVSAKTDCLVAGEKAGSKLTKAQDLGVKVMNEDDMLAMFADLEG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GLO2_ECODH
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: IF4G_DICDI
Sequence: MNFRYQPNQQPYQPPQHNNNSNNRGIPTNYQQYPPQNYQQYPPQQYYQAPINPQQFYPGPPQQPNFVSQQTGPIPQQPPGFNNQSPIPQQQPQQPQQPQPSQPSPIPQQPLSPQSSSPSSPQHVVIQPNQPNQQQQNANRKQSALKPSVQHNTIPNIPRTHSAPPSLEEQQQQHQHQNNIKGFTPEKRTPIQHSPQYVIPPQQFGKPIYPNPQQMYFQQQPPYPYYGQPPVVPVVNQMIPQTTVKKTLEIIDPKTNEKVIITSPPKSSTNSTVLPTSNTSSSSSSPTNANGSSTPSGSGYVTSFSSGNVNLRKNKQSGETTPIKQDAASTTTSTPATPSSKAESTTEAETTSKPSTPTTVDSVSSTTTPDKSNVVTAAATTTAAATTTTTTTDTTTTTTTPEAETSTTTPATEVQSPVETTKEEQPKEEVKPTEVQPPVEPTKEEPIKEEPTNEEPTKEEPAKVEPIKEEPSVVESTTTDTKEEPIIVAEEKKQEETPVTPVTEKKEEPIVKPETPVTDSTAASTTVEKESTDSTTTATVSTTAAATTTNGKVEEELEEWEKKGEEDFNIVQSSDSSTSITPATSLVFRNSGEKIVYSKELMMSLKPKSMEEPTGPLKDLKNQIETNTNQNQLNRSGNKIGGNQQNKNMGMGGMNMNPNYPPQMNMKYPPQMNMKYPPKNYNNQVQGQQQQQQGNPNFNKYAPGYQYQQQIQQGMPPPTLQPNPYQPQQATYGITFSRDPVQPSISSQPVNEKRWVPTKVNALDDSQKVLRKANFILNKITPEKFDVLTEELLELGIVDDEKVHKGTIDLIFDKALNESKFCTMYTNLCKKIFEFEKVKKEIAKRAVFEKIGVIETENYHKMSNKQRDEFDQEHNVKAVFRTLLLSTCQKEYEKIPFETVDKVPEDLKPEEKTDFEEGQFKERKRIFGLIKFIGELFKQQMLSEKIVHGIMVSLIGELQRPSEIKLECFCKLLSIVGKTLSQNEQASKYLTSYFQRMQQLVDNSQTLSQRIRFLIQNVMDLKNSNWTLKVDESAKTLKEVEATQNKQEDNRKSNPTGVKNTSNVKNMFNASFNFGGPNVKPMMAPPMNYNKNAPGIKPPAQFQPKPYPYNNNYNNQQQQQQHFGGGNNMMNNNNNNYNRGPMGNMNNNMNNNMNNNNMNNMNSNNSTSNNSANSEIQKKWDAVSTSITDSINEFLELKDEEEFMECVKSYVPSTDLYPHVISQLISTACSKQKDEPLIKKLIFASVFDKKLFTTAQFKSGYELFISSLPDLFEDRPSAFKSVASVFYSFVLNQEGLITITQFANAFTKVLDDCGSSIPKILFEFILQFEDPKKAAQLFVDNKVGVQGFFTEKDFSKITQTAISYNKDLQPFFDIVKL
What is the function of this protein?
Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
What are the official names of this protein?
Eukaryotic translation initiation factor 4 gamma, eIF-4-gamma.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: FMAJ_DICNO
Sequence: MKSLQKGFTLIELMIVVAIIGILAAIAIPQYQNYIARSQVSRVMSETGQMRTAIETCLLDGKKADECFIGWTKSNLLGASGSPSSSNDSTADHPGQGGLVIDYKLEADATNAITATFGQNAAATLHGKALKWTRDPKATWSCSTDVELKFRPTGCKDDLK
What is the function of this protein?
Major component of the type IV fimbriae that plays an essential role in twitching motility, natural transformation, and protease secretion.
What are the official names of this protein?
Type IV major fimbrial protein FimA, 351 antigen, Pilin, Serogroup H.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: RSMG2_SYNFM
Sequence: MRNGTIRYPGSDAAPGPDEMSAILRRCGIRLAPARIGQLWTYHQLLREFNPELNLTRIHNFANMVLKLYVDSLLPMNLVELPSPLMDLGTGPGMPGIPIKIAMPELEIVLAESRQKRAAFLKMAVERLKLEKVEVVGKSVGSSFEVPVKGVITRAVESVGATLERIAGCLDRDGLAIFMKGPQCDAEIGEALKRFRGEYRLWRDIHYTIPHTRNERRLVVFQRLGPPTRIRKETAMKRHGFRKIESENNDLYRDIRKLLTSRGIRKQQRALVSGSKQVHETLRDFPDDCLAWIAPGQEMPPPEGAPGHMSWYQMAPALFETLDVFGTRTPLLLIKVGEIETWDPVEGFPAGCSVLVPFQDPENVGAVIRSAAAFGAVQVILLRESAHPFHPKALRASGGAVLRMKLRNGPPLENLPENLPILPLSAEGRDITRHVFPAAFGLLPGLEGPGLPDNWRRKSFAIPICKDVESLNAATAAAIALYAWSRSGSQTKHSPAPA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G 2, 16S rRNA 7-methylguanosine methyltransferase 2, 16S rRNA m7G methyltransferase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOAT1_CHLAE
Sequence: MVGEEKMSLRNRLSKSRENPEEDEDQRKPAKESLEAPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQRWATGYSKSSHPLINSLFHGFLFMVFQIGILGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMQFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVMMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
What is the function of this protein?
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol.  Plays a role in lipoprotein assembly and dietary cholesterol absorption.  Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions.
What are the official names of this protein?
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRPC_LEGPA
Sequence: MNSILERIAKHKLEEVAVAKKNKPLHVLSKQQPGEMRDFITALKSNTSPAVIAEIKKASPSKGLIRKDFNVAEIAKIYTQNGARCLSVLTDIEFFQGHPDYLALAKSKTTLPVLRKDFIIDSYQIYESLVLGADCILLIVALLDDVQLMDFCQLAQELKMSVLVESHTQDELERALRLPTPLIGINNRSLHNFKTDIQLSIQLKQFVPKDKIIITESGINTREDIKLMQSHGINAFLIGESLMRADNIGKALQKLMTD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: DHH1_NEUCR
Sequence: MSDQLADQLKATSLSSGPEDWKKGLNLPARDTRQQTEDVTNTRGLDWEDFIHDRDLLMGIFEAGFEKPSPIQEEAIPVALTGRDILARAKNGTGKTAAFVIPALNKINPKVSKIQCLILVPTRELAMQTSQVCKTLGKHLGINVMVTTGGTGLRDDIVRLQDPVHIVVGTPGRILDLAGKQVADLSECPMFIMDEADKLLSQEFTPVIEQLLQFHPKDRQVMLFSATFPLSVKDFSDKNMTSPYEINLMDELTLRGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMAQQARNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLINWDDRFNLYNIERDLGTEIQPIPQTIDKSLYVYENPESIPRPISTFKPIAQQPQQQLQQSQRPQQSQQQQHFSTQTQPSNQLPPQQGNQQLGFNPQAQQPHRPIPQAQGDWQGQNGRQNGTGASNNQPRPTNYQNNRGQPGSSRGGRGRGFQGQGGRQNQNYGGQRGPRTQGQGQPQGPLSAQ
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dhh1, DEAD box RNA helicase 10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: ENGB_BURMA
Sequence: MAFLLHQARFFTTVNHLRDLPPTVQPEVAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVAHLVDLPGYGYAEVPGAAKAHWEQLLSSYLQTRPQLCGMILMMDARRPLTELDRRMIEWFAPTGKPIHSLLTKCDKLTRQESINALRATQKSLDAYRDAGYAGKLTVQLFSALKRTGLDDAHALIESWVRPAAADEDRAAVAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CCAP_CONVL
Sequence: MVSLGHVLFVILLPVLLPVAADDPDDQMLSQISLPSSSRSEYDDNDVSKRVFCNGFTGCGGRHRDRSRRQERYGKRLIPVLAKRPFCNSFGCYNGKRSLSGAGPALSTPVDPSRNNKARTMARMLDAAASARHEQQQQLLQQREQRGLESRDPAASGDLSKRLFCNGYGGCRGGKRTLYSPWLERMNEVADDRSARNALCTRLGWRE
What is the function of this protein?
Synthetic conoCAP-c decreases the heart frequency of 12% in Drosophila larvae.
What are the official names of this protein?
ConoCAP.
What are the subcellular locations of this protein?
Secreted.