PharMolix/UniProtQA huggingface dataset:
Protein: HECA2_HUMAN
Sequence: MGQDAFMEPFGDTLGVFQCKIYLLLFGACSGLKVTVPSHTVHGVRGQALYLPVHYGFHTPASDIQIIWLFERPHTMPKYLLGSVNKSVVPDLEYQHKFTMMPPNASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTRLAYQWLKNGRPVHTSSTYSFSPQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPIIYYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSADSHPPNTYSWIRRTDNTTYIIKHGPRLEVASEKVAQKTMDYVCCAYNNITGRQDETHFTVIITSVGLEKLAQKGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKVIKQKLEGRPETEYRKAQTFSGHEDALDDFGIYEFVAFPDVSGVSRIPSRSVPASDCVSGQDLHSTVYEVIQHIPAQQQDHPE
What is the function of this protein?
Required during prometaphase for centrosome maturation.  Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.
What are the official names of this protein?
HEPACAM family member 2, Mitotic kinetics regulator.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=In interphase, localizes to the Golgi apparatus. Localizes to centrosomes and spindles during prophase, prometaphase, and metaphase of mitosis, and to midbodies at telophase. Translocation to mitotic centrosomes is the result of poly-ADP- ribosylation (PARsylation).
Protein: GPI7_CANGA
Sequence: MLFLLVVAHAIAVLIFGCGFFPQKKVLDGHAALDGTHARDPVFDKLVVVVVDAMRSDFLFDASISKFHFIHEKLADGSAWGFTAHSNPPTVTLPRLKGITTGSTPNFLDAILNVAEDDTSSSLLAQDSWLWQFRNNAGKRIRFFGDDTWLKLFPPVEANEDSQTMFDEYEGTNSFFVSDFTQVDLNVTRHIDRQLRETSEWDVLILHYLGLDHIGHKDGPYSRFMGPKHEEMDSIIRKLYDELDMQSTLLVLMGDHGMNDLGNHGGSSAGETSAGMVFLSDKLAAYKPSKEQSSAKEFPMKIPSLNAGEEKTFHYLKKIQQIDVVPTISSLFNVAIPKNNVGVIIPEFLQLFKDVSLQKAIVKENWNQLSGLTKGKTQIMEETKNFVIEDVIKNMKDVQENLAKTATDYNYPLLFIGCFLSIVITGTIYYRYARHVAININTSILIAIAALMGISVFGSSFIEEEHQFWWWIITGLVLLSMVNLNFSSWKSHIIVLFCLRLIRGWNNSGQKYTYDNVIANLLKGNIDALWWLNLITVTVVGLNLKSLRFGNHTVSLLGFSDLLSMGLLSMITFLYKVNWSIVNGERVPDLFYKWVLETASLIVEDATLYREEDLIHTALIPLARIFFKLFFAVLVSRLMIQKFFQVSDISKSLAVVSRYVTIFLVFQTPSHNIGLFLFFEIINEITVHIIRERYQSDYLLAVIFGIILQFFTFFQSGGTNSIATVDLSNAYNGVSENYNIYVVGLMMCISNFAPTIYWSFYNWRITYANANSSRWQTLVAAKYPFIIIQSTIGCCLLLACIILRYHLFIWSVFSPKLCYYMVWTIFVGIIVHWIPEILLLLT
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI second mannose (By similarity).
What are the official names of this protein?
GPI ethanolamine phosphate transferase 2, Glycosylphosphatidylinositol-anchor biosynthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IGA2_HUMAN
Sequence: EVQLVETGGGLIQPGGSLRLSCAASGFTVSNHSMSWVRQAPGKALEWVSAIYRGGTTYYADSVKGRFTISRDDSRNTVYLQMNSLRAEDTAVYYCARDLAAARLFGKGTTVTVSSASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNSSQDVTVPCRVPPPPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVEGPPERDLCGCYSVSSVLPGCAQPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTYAVTSILRVAAEDWKKGETFSCMVGHEALPLAFTQKTIDRLAGKPTHINVSVVMAEADGTCY
What is the function of this protein?
Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).  Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
What are the official names of this protein?
Immunoglobulin alpha-2 heavy chain, Immunoglobulin alpha-2 heavy chain BUT.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: MNMA_ZYMMO
Sequence: MSIDFQIDKPKSAQRIVVAMSGGVDSSVVAALAKATGAETIGITLQLYDHGAAVGRKGSCCAGKDIRDARAVAEKIGIPHYVFDYENNFKESVIDDFVSEYVAGRTPVPCIRCNQGVKFTDLLNVARELGADCLATGHYVRRLVNNDRVEMHRALDPARDQSYFLFATTKEQLDYLRFPLGGLPKPKVREMAAELGLSVAMKADSQDICFVPDGDYARIVEEKCPESGQGGDIVDMQGRVLGKHSGLIHFTVGQRRGLEIGGQKEPLYVIRLDPAKKQLVVGPRQALAVAKAEIKEVNWLVDGFDREMQVKIRSAAKPVSARFDGKELVFEKPEYGVSPGQAAVFYDGDQVLGGGWIKETTPAVFDDLAE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ECO8A
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQSALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: PDXY_SALTY
Sequence: MKNILAIQSHVVFGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIVQGIADIGQLAHCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRYALPASDIIAPNLIELEILSKHSVNNVDDAVQAARELIAQGPEIVLVKHLARAGYSSERFEMLLVTAQEAWHISRPLVDFGSRQPVGVGDVTSGLLLVKLLQGATLQQALEHVTAAVYEIMIATKTMQEYELQVVAAQDRIANPEHYFSATRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: FB286_ARATH
Sequence: MILRKLPGKQALICRCVSKTFLSVLDSPCFMERHLRDDHDDGEPPALLTYGVHDVAVFYKLWMCKTMLEESDEAKVLKVDDRHLWNYPCIETQSYFHPISSGGLILTRCNSNSPFVFNPIRKEVMKIPAQGDENAWKQPLGFGYDPKGNTHKIISVWETQEHVLVAEIFSLGDTDTKWRSLDISSSASALPFGHVSFSSSTVTIGGYVYWTATISEGSQGACTCGCRSAETGYRLETKNWTKHMVLYRRHLSGFLTQLSSRGLSSNSSASLIFEGPWQWWIFLPRSV
What are the official names of this protein?
F-box protein At5g48550.
Protein: FABZ_STAAM
Sequence: METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHBL4_TOXGO
Sequence: MVWTSAVVMASPHGSASRAGSNRRTDGLSVNLGQDNTLKHDTPTETAPSASPPRVAPAPIPPKGGPAATPGKDGALDNRGSHDSVPPVAVAIPGREEVNATASQKSVVAGANSQPTPGTQSSKAPASDVDGSSKHGSPEHPDAGSPEVNAEGVPVEEALQAIGDDDPLIHNLPDGVVGRRAPANPFNSSMYAKLRGKKKKHRPKVRDPKLNNNPLRGRLVVCISTTALLCWIYMWELIYNFTSFNGRCVSPVMYPDYKLQEAKQRQPYVIRYGYGGCEYNLGSLAYPRASFGTSAGDKGWPVDLVPNGSAGSAATSWDSPNARVLRHLGGLETNYIREYSETFRLFTSMYMHGGWLHILINLSCQIQILWIIEPDWGFLRTTLLFFLGGISGNLLSAVADPCSITVGSSGSMYALLGALIPYCVEYWKSIPRPGCILVFMIVVIIGILTGMAGFTDNYAHMGGALGGILWGFASITTVSACDKCTLGERMAMTPPFSWCVPKATQQKLLERAKARKAEAIRRRKLQAIQKKKAGGARGKAMYAVKMRLQEEGRPPCKMSFREWVIRGLCAAALFAYWLILFLYLLDPSLYKSYSPPGQLKFSGWLYCKCGTIVYQAPQTYGNLGRFWCFGSEKDAQYYLEP
What is the function of this protein?
Putative serine protease involved in intramembrane proteolysis and the subsequent release of polypeptides from their membrane anchors.
What are the official names of this protein?
Rhomboid-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Uniformly distributed at the surface of intracellular and extracellular tachyzoites.
Protein: RSMI_ECOLI
Sequence: MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQG
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.  In vitro, active on the assembled 30S subunit, but not naked 16S rRNA or 70S ribosomes.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIQ_AVESA
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGG
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Ubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: H2B2E_HUMAN
Sequence: MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Has broad antibacterial activity.  May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
What are the official names of this protein?
Histone H2B type 2-E, H2B-clustered histone 21, Histone H2B-GL105, Histone H2B.q, H2B/q.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PCP_SULIA
Sequence: MTVLLFGFEPFLEYKENPSQLIVEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMKPILTLGIGVAPGRAKITPEKIAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGGFIHVPLHESYAARIQRPIPSMSLDTMIRGIRLSMEFILTNKKENLTFS
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB10_CALJA
Sequence: MDALATSINQFALELSQKLAESAQGKNIFFSAWSISASLAMVHLGAKGNTAAQMAQVLQFKRDQGVKSDPESEKKRKMEFNLSNSGEIHCNFQTLISEILKPNNDYILKTANATYSEKTYPFHNKYLEDVKTYFGAEPQSVNFVEASDQIRKEINSWVERQTEGKIQNLLSDDSVDSTTRMVLVNALYFKGIWEHQFLVQHTTEKPFRINETTSKPVQMMFMKEKLQIFHIEKPQALGLQLYYKSRDLSLFILLPEDINGLEQLEKAITYEKLNEWTSADMMEVYHVQLHLPKFKLEESYDLKSTLSSMGMRDAFSESKADFSGMSSARNLFLSNVFHKAFVEIDEQGTEAAAGSGSEISFRMKVPSIEFNANHPFLFFIRHNKTNNILFYGRFCSP
What is the function of this protein?
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF.  May regulate protease activities in the cytoplasm and in the nucleus (By similarity).
What are the official names of this protein?
Serpin B10.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: VPS3_SCHPO
Sequence: MSDIELHESAIPKELDSPVTTIALYNNHLYFGTEGGDVFLYNFSNFQLNESPELVKKISLVSKSRVNRILAMPFLGAVFIHHGSFAEVYKEDDLTQLYPSISFKGLVEFCHPGQRIDEKSTYLIVTNTHLKLISFQKDGIILVKNELKYPNIQTARVNGHIVCLVTENSFELLDILTFDTTPLFPIIKYDSENNGLMYKPMIVLHSNEFLLITGSPKDAIGLFVDSQGNVTRSTLTFSFYPKHVFSTSHYVFAISSSSLQIIDINTLSLVKSINLKDDESFSFISRLTSVHFCDRQIFSKFSAVNTASTSKTSDTIERASFSKPSFIFLTNKSWGFGAEAHFMNKLEFSITIGDIEAPLRRVSKRLRNPKKYGITNDVAYLQSAYLEQISALQYWKQGQYENSLSLLETSKIDPRVVISLYPDLYHSELSYIAFQGVISFRKSILSVDDTVANVLKSNELFRDTDQYTQRQMIEITKENAYIMLMRYLKNYKKNTSISEYLLSSQRDVMLAVEHSLLLLYLNMDDLAAGTKNAKELLESGLTGVEDIKDVLIQKKEYYLLSVLLATVRDHDGVLQTWKKLITGDYEDRRFNDGLIKIREYLVNDIEPSTFWEFTTWLCKHDATEGTRVLLDKTVSGSISAEDVLEHLDSSQDDVLIDYLVKSNSVTHRALLLKLCVNKLLGSLLDHNDFKNRLETAIETFRELPCMEKPTYAQYLEQLWGDMSDFSTHLSFYYLCSINLMENVEEESIDKIKDILFDIHVDNLYLFPQLEHSFYKRKKNYEKALSVLVTNIHDYKGGEAYCLQIDDVYPQCWCNLLEKCISTGDGCSDFIKELLYRRPFSYTLSYVCEQIPDHWNLNLLADFLCILQKRNAERLNESQTRLTLEKSLSQNLEELFMAINRRNVALGKNEI
What is the function of this protein?
Required for sorting and processing of soluble vacuolar proteins.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the VPS3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BST1_KLULA
Sequence: MVQIDLPAESAVRIRYPTLTKKLRKRSTLVIIVGLLLLCIITSTHISHNFSGSDTPKCRSIYMYPSYARIDGFDSRHTKLAKKYHLYLYREQGKDKEPKHGDEIQLDGIPVLFIPGNAGSFKQARSIAAASANLYFDHKSTIQNSNAKNMDYFTADFNEDFTAFHGQTMLDQAVYLNDAVRYILSMYAQSAAYKESNRPLPKSVILLGHSMGGIVARLMLTLPNHIPESVNTILTLSSPHSTAPVTFDGDILKLYDRVNSYWTSAMNDMGSYFRNNVSVISITGGILDDILPADYTNLQGIVPESNGFTTFTTTIPELWTPIDHLAIVWCDQLRYLLAKYILEIVNDDAGGKTATLDIRMRKGRKFFLSGLERITDADKLIDKNLSAPAVDFSDTESVPENHLLVLNSSESMSTGYAFNISKSVDYSFEMLTSLVQFDIFFCKDIYGKDCINGFSSFSKVPHSTSLQKFPTDSSWGESVSPFRFISLNGSLLQGFQIIVFQGSMKKKEDFVLAKYSDDKSIETASDGLWKLSLFPFRMSLKNKHSFVHGLAFPNLWSSLISFNLKTTFSDEIDSMFRPMMRQYVNNPYETKWHLLAASSSHEINMHNISPFIPLDDTIDKSLNLMFFIPPGEEISLRLSINWKLTLKMLYIRFRLAFASIPISIIALVLCYQFYYYDSPDSKFISFDTGLMNVLNNHSLLIFLFLSVGPIAINHKAILTLLHYLDPISLSKPSSDSHMLNNNYMLGLRETFVWWIGPVFFIISVALLFIILRLINVIEFAVIKISSAITRYTRITFPDPLNDMTHHKLLFNNRQLLGVCFISLGVMVYVPYQFAFILVSLIQMWNCMKLAVFTNRNNAKYSNIHNYNVSFLMLTIFMIPINAPIVVVFLRNFAIRWETAFRSHHNFLAIAPTLLLTLRNSQCNIPIIKNRMNWLIVVSILGYLSFYSFMYGIRNLYWVYHISNILNGVLFFLTIL
What is the function of this protein?
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
What are the official names of this protein?
GPI inositol-deacylase.
What is the protein family that this protein belongs to?
Belongs to the GPI inositol-deacylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LACD_STAA1
Sequence: MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEPTVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKGRLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDAEEINIQKKAYIERIGSECVAEDIPFFLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGFAEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLCGRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase, D-tagatose-1,6-bisphosphate aldolase, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: FRDC_ECOLI
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones (PubMed:10373108).  The QFR enzyme complex binds 2 quinones in or near the membrane; 1 near the [3Fe-4S] cluster (QP is proximal to the [3Fe-4S] cluster, on the cytoplasmic side of the membrane) while QD (the distal cluster) is on the other side of the membrane.  It is not clear if both of the quinol-binding sites are functionally relevant (PubMed:10373108, PubMed:11850430).
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL9_PSEP1
Sequence: MELILLEKVANLGNLGDKVKVKAGYGRNFLLPFGKATVANAANLAAFEERRAELEKAAADKKASAESRAAQLAELEVTITATAGDEGKLFGSIGTHDIADALTASGVEVAKAEVRLPNGTIRQVGEYDVAVHLHSDVEATVRVVVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ECPA_ECOK1
Sequence: MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSIISGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Major subunit of the fimbria (By similarity).
What are the official names of this protein?
Common pilus major fimbrillin subunit EcpA, MatB fimbrillin.
What is the protein family that this protein belongs to?
Belongs to the EcpA/MatB fimbrillin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: NHAA2_KLEP7
Sequence: MSEVPSAFFSSPAAGGIVLIIASAAAIIVANSPLREGYEVFLKYNAAGLSVEHWINDALMAVFFMMVGLEIKRELLTGQLATWGQRALPGFAALGGMAVPAAIYVWFNAGSDETLAGWAIPAATDIAFALGVLALLGSRVPASLKIFLSALAILDDMGAVAIIALFYTSNISFLMLAGAAVTVALLFIMNRAGITRLFPYLLAGGVLWFFMLQSGVHATIAGILLALFIPLRVTDPDKQSPLARLEHGINPWVTFLILPLFGFANAGVALSGMTADDLMSPVPVGVALGLFVGKQAGIFGLSLLAVSLGLAKRPEKSTWLQVYGVSVLCGIGFTMSLFIGNLAFAESPLLVDEVKVGVLAGSVLAALAGMLILRFSPSHPSR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPF_BACMK
Sequence: MFRIGQGFDVHEFAEGRPLIIGGITIPHEKGLIGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: IF2_BORBU
Sequence: MSKNIDDIKNEDGKKVKIIKLKKKVVKIVTYNDLSVKNDSNSFVDLHNNSNKAEYSQSRDNRTGGYSQNRDNRAGGYSQNRDNRAGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRGGYSQGRDNRTGGYSQSRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDSLSFQYQGSVKKTYVAKNNSQNKYTTTSMSFRRLIKTKVPAIVSSTPAADSENSKELNRKLGEKKKQQQESQKSYKRKKAETESKTIEQKVFEQLQKKKRENLANPIPKSIDIMGSITVSDLARKMNLKSSDLIAKLMALGVMVTINEKIDSDTATILVEEYGSKVNVVSIYDETVIEEEVEDQSKRVEKPPVITIMGHVDHGKTKLLSVLQNIDINQTESGGITQHIGAYTIVYNDREITFLDTPGHEAFTMMRSRGAQVTDIVVLVVSAIDGVMPQTIEAINHAKEANVPIIVAINKIDLPDSNPDKIKHQLSEYGLVSEDWGGDTIFVMISALKNIGISELLDMILLQSDMMLLKANPSKRAIGKVLDAKIDLGRGIVCSVIIEDGTLYVGDSFVGGACYGKVKALISEKGVSVKSVGPAKAISVLGFSSMPQAGDPFQVTKTEKEAKLISSKRQDLKKYESSKNVKKVTMLNLYDSIKEGALKELKIILKADVQGSVEALKNSLEKLTNDEVRVRVVHSSAGVITETDISFASASDAIVIGFHVRPTAKAQVLADQEKVEIRKYNVIYDAINDVRSVLEGMLEPDVEQQFIGFAEVRAVINVPKIGVIAGCYVSRGLIKRDAITNVMRDGLQIHSGKISSLKRFKDDVKEVAEQYECGIMIDNYANIKEGDIIEAFEVKKVKKSFKT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX19_MAGOY
Sequence: MSAFGGPGGGQINQKPIPPQRGSFPLDHDGECKHVMTSYLACMKKVRGVNDNECREFAKSYLACRMDHNLMARDEFKNLGFQDVKDSSNKGDPAKKGELRW
What is the function of this protein?
Required for the assembly of mitochondrial cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX19.
What is the protein family that this protein belongs to?
Belongs to the COX19 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: YBJL_SHIDS
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKCLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVCPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.