PharMolix/UniProtQA huggingface dataset:
Protein: EMC10_DANRE
Sequence: MAPIRVLSLVLPILSTVTLLLTQFGECNNGRRSGDAVDTDFSGFSVPLEHSFEVDDVPRFRLRGALQFRGGRENSVYLSQNQLSEKDRNTLKDVAAVDGLYRIRVPRVSLQVDRQTERQYEGYLTAFVRACALVESHLSDVITLHTDVSGYVIGISIVTIPGSCRGIEVEDEVDLEVFNTTISVMAPVTAPVPETAPYIERMEMEMEKKGKNPQEQKSFFAKYWMYIVPLVLFLMMSGAQDQSGGGAGGGAANGGGR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.  Promotes angiogenesis and tissue repair in the heart after myocardial infarction.  Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
What are the official names of this protein?
ER membrane protein complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the EMC10 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: DAPAT_PROMT
Sequence: MVKVNADYLKLKAGYLFPEISRRITEFSSKNPNADLIRLGIGDVTEPLPLACREAMKAAIEEMGTKDGFRGYGPEQGYKWLREIISENDYISRGCEISAEEIFVSDGSKCDSSNILDILGKENKIAVTDPVYPVYVDTNVMTGRTGEANSVGEYKGLSYIPINSENGFEASIPKDKFDLIYLCFPNNPTGAVATKEQLVSWVKYAKENNSLILFDAAYEAFIKDESIPHSIFEIEGARDCAIEFRSFSKNAGFTGTRCAFTVIPKSLKGKAGIETVDLWSLWNRRQSTKFNGVSYVVQRGAEAVYSKEGKTQIKKLVSFYMDNAEIIKSNLTAAGFEVFGAVNAPYAWIKTPKDMSSWDFFDFLLEKANVVGTPGSGFGAAGEGYFRLSAFNSRENVEKAMQRIVKLK
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: S26A7_HUMAN
Sequence: MTGAKRKKKSMLWSKMHTPQCEDIIQWCRRRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRFPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKIISINNPLVFLNAKKFYTDLMNMIQKENACNQPLDDISKCEQNTLLNSLSNGNCNEEASQSCPNEKCYLILDCSGFTFFDYSGVSMLVEVYMDCKGRSVDVLLAHCTASLIKAMTYYGNLDSEKPIFFESVSAAISHIHSNKNLSKLSDHSEV
What is the function of this protein?
Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport.  May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger.  Plays a major role in gastric acid secretion.
What are the official names of this protein?
Anion exchange transporter, Solute carrier family 26 member 7.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Multi-pass membrane protein. Note=Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid- secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion.
Protein: SDHF1_BOVIN
Sequence: MSRHSRLQRQVLSLYRELLRAGRGKPGAEARVRAEFRQHACLPRSDVLRIEYLYRRGRRQLQMLRSGHATAMGAFVRTRGPTEESNGAGAPGTLSGEGDDPRKPLDSMRTPKTPLDGR
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF3.  Contributes to iron-sulfur cluster incorporation into SDHB by binding to SDHB and recruiting the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 1, mitochondrial, SDH assembly factor 1, SDHAF1, LYR motif-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RLR83_PLAVT
Sequence: MLVLLAATFFIYISRLTSTDALQLIQRGLRGKSETFDANATIVPEISESKRVIFGPKPTDLQHEEALVASYADPFKAALSIFKLLGANKFHQMTSSKTQLRYAFVKLRRWSQRPIAEPKRSWWQWRSKTGNKSRDDLAQKRGFRSWWSGRHKAKNAKRVA
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 83.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm. Note=Localizes to speckle-like structures within the nucleus.
Protein: MPRB_MYCSS
Sequence: MTLPPPPSRLKPPRNTSSLSLRWRVMLLAMSMVAMVVVLMSVAVYAVVSRALYDDIDNQLHSRARLLIESGSLAADPGKAIEGTAYSDVNAMLVNPGRSIYTANQQGQTLPLGEAEKDVISGELLLSLRTANHQRILAVHLTNGSSLLISKSLAPTGQVLGRLGTVLLIVGGVGVAVAAIAGGMVARAGLRPVGRLTQAAERVARTDDLRPIPVFGSDELARLTEAFNMMLRALTESRERQARLVSDAGHELRTPLTSLRTNVELLMASQAPGAPRLPEEEMAGLRADVIAQIEELSTLVGDLVDLTRDEAGGVVYETVDMAEVVDRSLERVRRRRNDIEFDVNVVGWQVYGDAAGLARAVLNLLDNAAKWSPPGGRVGVRLTQTDPVHAELVVSDQGPGIPEAERRLVFERFYRSTAARAMPGSGLGLAIVKQVVLKHGGALRVEDTVPGGNPPGTSFYVMLPGRPLTPGGNGTAPVPAAQFDPDMRSAGSRADRRVIKNTETNGKSRSASKEL
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS19_ENT38
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NBP35_EMENI
Sequence: MAPSFTETTSTYLEAPSKAPPNLVAPEPEHCPGPESDQAGQGDACAGCPNQSICASAPKGPDPDIPLITARLASVRHKILVLSGKGGVGKSTFSSLLAHGFASNPDSTVGIMDTDICGPSIPKMMGVESETIHISNAGWSPVWVSDNLGVMSVQFMLPNRDDAVIWRGPKKNGLIKQFLKDVDWGEMDYLIVDTPPGTSDEHLSVNSLLKESGVDGAVVVTTPQEVSLLDVRKEIDFCRKAGIRILGLVENMSGFVCPSCDHESKIFRATTGGGKRLAKKMGIPFLGAVPLDPRVGMACDYGESFVENFPDSPASLAIKQVVRAVGRFVGEDPDSVLPDAE
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nbp35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_CLOBH
Sequence: MIHTLETTVAGRKMKVDFGKTGMLSNAAIFMSYGDTVVMINANASKEPREGIDFFPLSVEYEERLYSVGKIPGGFIKREGKPSDKSILHARSIDRPLRPLFPKGYRNDVQIVNTVLSVEQDNLPEILAINGSSLALCLSSIPFTTPVAAVSVGLVDGEFIINPTVAQRENTILDLTVCATKERVMMVEAGGQEIDEETMYSAIMFGFEECKNIVAFQEEAVAKFGKTKNEPVLYKADEEVEKEVKSFAFDMIKEAMYIMDKDERNAQLDKVKEKISEEFSEKYEDKVADIAEVIYKTQKEIVRNMLLNEDRRPDGRAFDEVRPISCEVGILPRTHGTGLFTRGLTQVMTVATLGALGDVQILDGIAEEESKRYMHHYNFPSYSVGEVRPLRGPGRREIGHGALAERALEPLIPSQSEFPYTIRLVSEVLSSNGSTSQASVCGSTLALLDAGVPIKRPAAGIAMGLITSEDLEKEKVITDIQGIEDFFGDMDFKVAGTEKGITSIQFDTKIKGLSNSCVKDALEGAKKARLHILGKIKECIPEPRKELSKYAPRTEIICIDPEKIRDVIGAGGKVINKIIADTNVKIEIKEDGKIFVTSNNEPEGVKKAISIIEGLTKEVVQGEIYLGKVTKTTNFGAFVEILPGKEGLVHISKLDFARVEKVEDVVSVGDEILVKVTDIDNQGRINLSRKDAIAKKEEEKDK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6125_BURL3
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAGEGQHRLAVAIDARSSASLDEMPGLIRDLSREHDVRVLFLNASTQALIQRFSETRRRHPLSGSLSHDADVGLLSSLEEAIERERHLVAPLAEFGHQIDTSTLRANALRTWVKRFIEQKNNDLMVMFESFGFKRGVPLDADLMFDVRALPNPYYDHELRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFRDDNRSYLTVAIGCTGGQHRSVFIAETLAARLAHEANVIVRHRDAPVDVDASSRLVSEVDRP
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bcep18194_A6125.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RTC1_VANPO
Sequence: MSNYSCPRTHNKSNMSGRNEVKPISFSRGSFQIHHYSNSIHSPSLDGSPRQNFSQKYSFGSINSSNSSYDRSRDPSSVEQQLMREKSQALLKRKSSPMPKSSGLLYSTHTNKELSSIDKINDPSSNALICAGKAHLGYYKFSSNDNNKITLVHEFTQGFSSGSSQLNSLNPNLNKRRRQIKLSTIADVKSGFQKYNNYIAVCNNSTIISIYDINKNDNIDNPLVTSFSEHSRAVNSFDFNMTQTSLLISGGQDGQIKIWDLRSNSLSGSNKPDLNINAASDSIRDVKWMPGYNFSSFNQSYDGKQTGNSEYKFASIHDSGLLLKFDIRQPNQVEKKINAHTGPGLCLNWHPNQDYIATGGRDGKCCIWYIGDVVNDAPVTSLGSMTPNTLHTSNVNYYQSNATSLALPEMTINTGFPVTKLKFRPAYEKNVMDSLLAISSMGEEAEVNIYSLCRKFIPKHVLLTTSPSQGLVWWDKSLIFNTDRSNRINGWDIDLEPTVLDNLPKALATWRDIDGNGLLVIDQDSGTYTANEEYIPLVFDKRRRQSHRLLNPSINDNNSITKTKYLDSIKKANSNTIISPTSVEKTGNIKQPNLHSNKSIIGMTSPMYMTQFMPPTNSPSPLNEPLEFKGIQSPLIVALDFPHILNNMRLSKITSKKHLSKSSDIAAIKESPIQVFQYLARELEFSFSKDRKLDSRSSIIKRKSISDDSGSQVDVIKKIGFTDTTKWTNLINRKTDGEIAEKSSDRISALSTSSESIKNDIDEKSEHSKNNAYLNLEKKLSHGTHGMPEDAIEAQHKVDILIELVTICSHNASVYSYIDDVPNFKIWTLIKDSLLWDLKDITGIEEAINSNDSIEIKDKFQYFENLDHERALKNSSSQTQFSDIPSEIESFVTENPEALTSASLELDNDIEEGTKESKRPISNLQQQLKAENTAVMDTPSDVFVTATTDGGHFRDNSKVTRDENKIETNDNTNLLNIGKVNTENAIKIDSESVIEDVAPGSKSIEIPTLTRGRTRTSFIDTFMTNPLHNMERPDRSLLLAQDSAASLNDQSSPISKVSSIKSSSNVPHSLNSMIKLSQGKMHSRTRSIGKSPIKLSGFLSPKERSLSLPLENILKKNKSAEKVAHNDQFRPPWETGKLLKQLFNQAVETGNILLAINIITLFQDLYNITTIDVVKSSLLQFVEILHRYELFEIATALLKYCSWNNILEGNGGNSTVQLFCDKCGKLIVNEFSKTNFNEELKRTGNKDSMKKFGYWYCDACKKPNSLCVLCEKPMKKLVMCVLACGHEGHFQCLRDWFLNEGMNECPAGDIQVI
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: FBL58_ARATH
Sequence: MDRISNLPNEIICHIVSFLSAKEAAFASVLSKRWQNLFTIVQKLEFDDSVKNQGSLMDFVNGVLALPVTTRISKFSLRFDSFLKRKLETGLVIGPHVVNRCLCNVLKRGVLDLKLEIYGEDGYLLPSEVFTCKTIVDLKLTSCIFAESYVIDVIPENAFLPGLESLFLKSIWFSDLRGCAFQTLLSACPVLKTLTIYDVQWEKWKWSRTVSSATLERLIIQRTEFTYFNGSDFKSITFDTPSLTYLKYIDFVPEEYPVVNLDSIVEAKLHLILTGNQDYPVRYLGREDDPITSNPTNLIKGLRNVEILHLSTATAQMLCFFPRETLPEFVNLHHLTIGPTYYECFNWRLLPILLKKTPNLKTLMIKGPLHLYYRDFNDDEEEEEPEYYCECSSGCNCLLSCHMEVLEISHYRGTTKELEKLKHFLGKLSCLEHVKLGVWASSDKEKLSITTDLLMLPRASVNCKIQINFS
What are the official names of this protein?
Putative F-box/LRR-repeat protein At3g58920.
Protein: STM1_CANAL
Sequence: MSFQNKNLYDLLGNDVEEDAAPSAPSREVVKKNTSSKKSDAAPASADPAKAKKKKSPTGNEAALKNKNFNKDVAPPQSTATKHSKKPFDRHSRTGKTDSKKKLQQGWGQSDKRELEGEVEGTEDAEAELEAEAEENDESANAIPKKSLQEYLAELELSKQELEGSKKLRQANEGAEQKWTAEEKIEKQQEVFFASTHTKKAKSKAQKEKVFLDIDANFGDEQPQTTRGGFRGGKRGGARGGSRGGAKRGGARGAAKPEVNDKNFPSL
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein CAALFM_C304810CA.
Protein: KDPC_CLOD6
Sequence: MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIEVNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNYGATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAIAKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: KCY_METBU
Sequence: MLLTISGLPGSGTTTVGKLLAEHYSVDIISAGDVFRGLAKERGVTLAEFGRLAESDPSIDVEIDKRQSDIANSSDNLILEGRLAGQMAKKALKIWIKAPLEVRVKRIVDREGSSFDVRMQETVEREASEALRYKEIHSIDIHDLSVYDLVIDSSRWDQFVITDMLKKAIDASGSF
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICLN_RAT
Sequence: MSFLKSFPPPGSADGLRLQQPDTEAVLNGKGLGTGTLYIAESRLSWLDGSGLGFSLEYPTISLHAVSRDPNAYPQEHLYVMVNARFGEESKEPFSDEDEDDNDDVEPISEFRFVPSDKSALEAMFTAMCECQALHPDPEDEDSDDYDGEEYDVEAHEQGQGDIPTFYTYEEGLSHLTAEGQATLERLEGMLSQSVSSQYNMAGVRTEDSVRTYEDGMEVETTPTVAGQFEDADVDH
What is the function of this protein?
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity).  Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (By similarity).  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity).  Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus (By similarity).
What are the official names of this protein?
Methylosome subunit pICln, Chloride channel, nucleotide sensitive 1A, Chloride conductance regulatory protein ICln, I(Cln).
What is the protein family that this protein belongs to?
Belongs to the pICln (TC 1.A.47) family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton. Note=A small fraction is also associated with the cytoskeleton.
Protein: P2C19_ARATH
Sequence: MGCAYSKTCIGQICATKENSIRQTHQQAPSRGGTRATAAAAAVEEDNPVFNFSSDAVDDVDNDEIHQLGLSRDQEWGITRLSRVSSQFLPPDGSRVVKVPSCNYELRCSFLSQRGYYPDALDKANQDSFAIHTPFGSNSDDHFFGVFDGHGEFGAQCSQFVKRRLCENLLRHGRFRVDPAEACNSAFLTTNSQLHADLVDDSMSGTTAITVMVRGRTIYVANAGDSRAVLAEKRDGDLVAVDLSIDQTPFRPDELERVKLCGARVLTLDQIEGLKNPDVQCWGTEEDDDGDPPRLWVPNGMYPGTAFTRSIGDSIAETIGVVANPEIAVVELTPDNPFFVVASDGVFEFISSQTVVDMVAKHKDPRDACAAIVAESYRLWLQYETRTDDITIIVVHIDGLKDDAPRQLSSTGTQLQPPIPQVVELTGSESPSTFGWNSKNQRVRHDLSRARIRAIENSLENGHAWVPPSPAHRKTWEEEAHIERVLRDHFLFRKLTDSQCQVLLDCMQRLEANPGDIVVKQGGEGDCFYVVGSGEFEVLATQDGKNGEVPRILQRYTAEKQSSFGELALMHNKPLQASVRAVDHGTLWALKREDFRGILMSEFSNLASLKLLRSVDLLSRLTILQLSHVAESLSEACFSDGQTIVTKDQKLQGLYVIQKGRVKISFCTEVLESQNVSSLTTGITNEYDNLEIGTEVSIEKHEGSYFGEWALLGELKDSLSVVAVGEVVCVVLTKENFESAVGPLTNISDDGPKTRHSSFELSKESAKVTDTTALAKATLADLEWTTCLSTTDCSEIGLVHLKDKENLLSLKRFSKQKVKKLGKEAQVLKERNLMKNVIKPSAIVPEILCTCVDQTFAAILLNTTLACPISSLLHSPLDESSVRFITGSLVSAIEDIHKNEILFRGSSPELLMLDQSGYLQIVDFRFAKKLSGERTFTICGNADYLAPEIVQGKGHGYAADWWALGVLIYYMLEGEMPFGSWRESELDTFQKIAKGQLTFPRVLSSEAEDLITKLLEVDENLRFGSQGGPESIKKHPWFNGLKWEAISNREFQVPQEIISRIHHHLENDNVLPLETSKSLDTTEDQDAQNWLEEW
What are the official names of this protein?
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: YL534_MIMIV
Sequence: MMKSTNRSSLILSSNKFVCNNITNGKPMNIPVKNHNKYSSEPVSRSWGQIYSNNIDRYNLHNSKLSKKKYNKSPYYSDTYYVNYDNNDFNNRPYDAIKNCKSAGIIPYTFKNGELYFLFQRAEDPQRKKDSGWNDFGGKQLNSSETTADIAAREFSEETSCLFYLLEKLSIESNNNNNNNIKFKDLYDLLKNNDDLFYSRETIVNLKKLIIESKKFYSDKITEYVLPIFLSSKETYISYFVRVKYIPESDLPKAEDFHIPYEDRYLRECRWFSLDDLMNLNEKDFHKRLQITRIQQRIAKYYEKGLFS
What are the official names of this protein?
Uncharacterized protein L534.
Protein: RSMH_ANAMM
Sequence: MVHKPVLLNEVVEALSPKDGSVYVDATFGGGGYSRRILETAQCVVYAIDQDVVVKKYFDELLQSFPGRLNLAISRFSKLREVVLSFGVDKVDGVVFDLGTSAMQLADASRGFSFMNSGSLDMRMCSSALRDAAMFVNTVPEKEMADVIYQYGGERYSRRVARAIIDARRKCRINNTGDLATIIRSAVPRSRVHPIDPATRTFQAIRIWVNNELEELQAGLETAAEVLKIGGKILVTSFHSLEDRVVKHKFRSLCDMGFSLINKKAIMPTDEEVKNNPRSRSGKLRAIARVE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP2AA_BACSU
Sequence: MSLGIDMNVKESVLCIRLTGELDHHTAETLKQKVTQSLEKDDIRHIVLNLEDLSFMDSSGLGVILGRYKQIKQIGGEMVVCAISPAVKRLFDMSGLFKIIRFEQSEQQALLTLGVAS
What is the function of this protein?
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.
What are the official names of this protein?
Anti-sigma F factor antagonist, Stage II sporulation protein AA.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: DGCT_ECOLI
Sequence: MEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYLMVMIALFFIDTVAFIFMQLYFIYDRRQFSNCVLSLAFLSCLIYFVITVIIIQQIIEERLTSSVVQNDIAIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFGGPIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRYDIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALRVTKNIAHRDPLTNIFNRNYFFNELTVQSASAQKTPYCVMIMDIDHFKKVNDTWGHPVGDQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGDNPEYAIPQKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCESP
What is the function of this protein?
Probably catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules.  Overexpression leads to a strong repression of swimming; swimming returns to normal when residues 359-360 are both mutated to Ala.  Overexpression also leads to a 20-fold increase in c-di-GMP levels in vivo.  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.
What are the official names of this protein?
Probable diguanylate cyclase DgcT, DGC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS18_STRPI
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: M1_I96A3
Sequence: MSLLTEVETYVLSIVPSGPLKAQIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTESAFGLICATCEQIADSQHKSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSTGLKNDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: RNH_CHLPD
Sequence: MQKKIIVYTDGACSGNPGKGGWGALLMYGASTREISGYSPATTNNRMELSAAIEALETLKEPCIVHLYSDSSYLVNAINEGWLKRWTANNWKTAAKKSVENIDLWQKILTLIKLHDVTFHKVKGHSDNPYNNRCDELARQAIKNNR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.