PharMolix/UniProtQA huggingface dataset:
Protein: PDXY_PASMU
Sequence: MKHVLSIQSHVVYGYAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPKEQIGEIVRGIDAIEALHLCDAIVSGYIGSAEQVEEIVNAVRFIKSKNPNALYLCDPVMGHPDKGCIVAEGVKEGLINLAMAEADLITPNLVELRELSGLPVENFAQAQDAVRAILAKGPKKVLVKHLSKVGKDSSQFEMLLATKDGMWHISRPLHQFRKEPVGVGDLTAGLFIANLLNGKSDIEAFEHTANAVNDVMTVTQQKDNYELQIIAAREYIMQPSSQYKAVKIA
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: 6DCS_SOYBN
Sequence: MAAAIEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPLRKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQNLHIFDWALTEQDHHKISQISQSRLISGPTKPQLADLWDDQI
What is the function of this protein?
Co-acts with chalcone synthase in formation of 4,2',4'-trihydroxychalcone, involved in the biosynthesis of glyceollin type phytoalexins.
What are the official names of this protein?
NAD(P)H-dependent 6'-deoxychalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: LEU3_DESHY
Sequence: MPKIAVLPGDGIGQEIIPQAVRVLKAVLAETDAEFEFQDYPIGGAAIELVGKALPDETLQGCREADAVLLGAVGGHQWDHLPASERPETAALLGLRKGLNFYANIRPVRMIPSLLATSTLKENVLDGVDMVVIRELTGGVYFGEKGRSDNPRSAYDKMTYSEEEIRRILIQGFETAMLRSKKLCSVDKANVLETSRLWREIANELAKEYPEVELTHMYVDNAAMQLVRNPKQFDVIVTENMFGDILTDLASMLGGSIGMLSSASLSGTQGMYEPAHGSAPDIAGKNLANPLATILSAALMLRYSFGMEAEALRIESAVEKVLEQGYRTGDLAQAGDKVVGTIEMGDAVLAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_DESPS
Sequence: MYRENHHIHFVGIGGIGMSGIAELLLHLGYSVSGSDLRSSATTKRLQDLGATIYEGHQAASCAGASVVVTSSAVAEDNPEVVQAREDKIPVIPRAEMLAELMRLKTFGIAVAGSHGKTSTTSLIGCLLSQTGFDPTIVVGGKVDSFGGNAKLGEGDFLVAEADESDGSFLKLSPVLEVVTNIDLEHLDYYTDIEHIKETFLSFIDKIPFYGAAIVCLDDENVAAILPQVQKRLITYGLTPQADVSADNLRFAAGRSTFRVRAAGEVLGEISVFPSGTHNVYNALAAVAIGLELEIPFGKIATALASFGGVQRRMQHKGEGKGITVIDDYAHHPTEIRASLKAIKETWPEKRLVVLFQPHRYSRTQALFEEFKTCFHQADCLIMTDIYEASESPIEGVSTEILLEAIKAHGQRYTRHIPEIASLATEVMPNLREGDLVVTLGAGNIVQAGEEICQLLGQE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_WIGBR
Sequence: MIRNFRRRKFCRFTLEKINNIDYKDIILLKNYITENGKIVPSRITGTRARYQRQLSRAVKRARYLSLLPYTDHHR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SEC11_PARBA
Sequence: MLSSLAPYMANPRQTLTQVLNFALVLSTAFMLWKGLSVVTNSTSPIVVVLSGSMEPAFQRGDLLFLWNRSPRVDVGEIVVYNVRGKDIPIVHRVMRSFPELPGREDKKSVKKGGEEGEETSSTPSQKLLTKGDNNMADDTELYAQGQEYLDRKEDIVGSVRGYVPGVGYVTILLSEHPWLRSVLLGFMGLMVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NLRC4_BOVIN
Sequence: MNFIKENSQVLIQRMGMTVIKQILDELFVWNVMNYEEVNVICGEKFEQDAARGVIHMILKKGSEACNLFLKSLEKWNYPLFQELHGLSLFHQMSEEDLDDLAQELKYFYQSPSFLNFYPLGEDIDIMFNLKSTFTEPVLWKKDQHHHRLEQLTLSGLLDTLQSPCIIEGESGKGKSTLLQRIAMLWASGECQALTKFKLVFFLRLSRAQGGLFETLSDQLLDIPDVISKQTFMARLLKLRQRVLFLLDGYNEFKAQNCPEIEALIKENHRFKNMVIVTTTTESLRHIRQFGALIAEVGDMTESSAQALIQEVLRKEFAEDLLLQIQKSRCLRNLMKTPLFVVITCAIQMGKSEFHSHTQTTLFCTFYDLLINKNRHKRKGLAPSEVTQSLDHCGDLALEGVFSRRFDFEPDDLSNVNEDVLLTTGLLCKYTAQRFKPKYKFFHQSFQEYTAGRRLSSLLTSGEPAEVTKGNGHLQKMVSISDITSKYSNLLLYTCGSSAEATRTVLKHLSSVYQHGSLLGLSVTKRPLWRQESMQNMKSTTVQEILKAININSFTECGINLFHESISTSSLSKEFEDFFRGKSLYINSENIPDYLFDFFEDLPNCASALDFVKLDFYGGAVRDISGNQDQEFSGTYIPSRAVSLFFNWKQEFKTLDVTLRDFCKLSKKDIKYLEKIFSSATSLRLHIKRCVGMAGSLSSVLSTCKNIHSLIVEASPLTLEDEQHITSVTNLQTLGVHDLQIQRLPGGLTDNLGNLKNLMKLILDNIQMNEEDALKLAEGLTNLKKMCLLRLTHLSDIGEGMDYIVKSLSAEPCDLKEIQLVSCCLSGNAVKTLAQNLHNLARLSILDLSENHLEKDGKEALQQLIDRLHILEQLTVLMLPWCGDVRVSLARLLEQLERVPQLVKLGLKNWRLTDAEIRILGVFFEKNPLENFQQLDLAGNCVSSDGWLAFMSGFENLKELVFFDFSTKGLLPDASLVRKLSHVLSKLTFLQEVQLVGWQLDDDDVSVLKGAFKLVIA
What is the function of this protein?
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis.  The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria.
What are the official names of this protein?
NLR family CARD domain-containing protein 4, Ice protease-activating factor, Ipaf.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSBK_ADICA
Sequence: MTVSYSIYLENSLHFGDALLAKLPEAYAIFDPIVDVMPVIPVFFLLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CH60_HELPH
Sequence: MAKEIKFSDSARNLLFEGVRQLHDAVKVTMGPRGRNVLIQKSYGAPSITKDGVSVAKEIELSCPVANMGAQLVKEVASKTADAAGDGTTTATVLAYSIFKEGLRNITAGANPIEVKRGMDKAAEAIINELKKASKKVGGKEEITQVATISANSDHNIGKLIADAMEKVGKDGVITVEEAKGIEDELDVVEGMQFDRGYLSPYFVTNAEKMTAQLDNAYILLTDKKISSMKDILPLLEKTMKEGKPLLIIAEDIEGEALTTLVVNKLRGVLNIAAVKAPGFGDRRKEMLKDIAILTGGQVISEELGLSLENAEVEFLGKAGRIVIDKDNTTIVDGKGHSDDVKDRVAQIKTQIASTTSDYDKEKLQERLAKLSGGVAVIKVGAASEVEMKEKKDRVDDALSATKAAVEEGIVIGGGAALIRAAQKVHLNLHDDEKVGYEIIMRAIKAPLAQIAINAGYDGGVVVNEVEKHEGHFGFNASNGKYVDMFKEGIIDPLKVERIALQNAVSVSSLLLTTEATVHEIKEEKAAPAMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE2_NITHX
Sequence: MTRFQVSLVSPESLLFSGQVDQVDLPGIEGDLGVLAGHAPIVVMLRPGIVTTVAGDIRDRFVILGGLAEFSQGELTILADSASSVDGFDLTRLKAQIDEMQESLAKQSVGDELDRAVAKFDHFKAIHTALAPATAF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain 2, ATP synthase F1 sector epsilon subunit 2, F-ATPase epsilon subunit 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYMM_DICDI
Sequence: MLKLLKQISTTSTFKKPSSINNGFININLFKNYCTSVKQEDKKKVLITTPIFYVNGPPHIGHLYSALLGDALGRWNRFIGNDTLFMTGTDEHGSKVDEAAKKNGLKTIDYCDKISNRFRELFDKADIKYDDFIRTTEPRHKEAVTAIWNRLLERGYIYKGVYKGWYCTSDESFLTDDQVTEGMSPITPQNPISKKCMISLESGHEVNWIEEENYMFKLSEFSKTIENWFEEVKPIFPAIHVNLLRYMLSQGIKDLSISRPSSRIPWGIEVPNDPSQTIYVWLDALTNYLTVTGYPNVSPNSSQSHWSNATHIIGKDIIKFHSVYWPSFLIAADYPLPKSIICHAHWTVNREKMSKSRGNVVDPFLAIDNHGLELIRYFLLKGGGLENDGDWSEHELAVRFKSDLADTYGNLISRCTGKALNPSGEWPKSVTDTSLFTMDDQKLIENSSILVKSVSTHYDRGDFKSGIFEIMTFLYECNLYVQNQAPWKLVPKPNRVGSDLIRLNTIIYIAIEMIRITSLLLSPIIPTSSNLTLNYLSIPLENRSNPSNFKFGYNYHQNQNNLKLPKEILILFHKK
What are the official names of this protein?
Probable methionine--tRNA ligase, mitochondrial, Mitochondrial methionyl-tRNA synthetase, MtMetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LIT1_MOUSE
Sequence: MARNAYFILLSCLIVLSPSQGQEAEEDLPSARISCPEGSNAYSSYCYYFTEDRLTWADADLFCQNMNSGYLVSVLSQAEGNFVASLIKESGTTDANVWTGLHDPKRNRRWHWSSGSLFLYKSWATGSPNSSNRGYCVSLTSNTGYKKWKDDNCDAQYSFVCKFKG
What is the function of this protein?
Might act as an inhibitor of spontaneous calcium carbonate precipitation.
What are the official names of this protein?
Lithostathine-1, Islet of Langerhans regenerating protein 1, REG 1, Pancreatic stone protein 1, PSP, Pancreatic thread protein 1, PTP, Regenerating protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKGC_PIG
Sequence: MPPQLSNGLNHSAKVVRGTLDSLPQAVRDFVESSAKLCQPDQIHICDGSEEENQQLLSHMEEEGVIKRLKKYDNCWLALTDPRDVARIESKTVIITQEQRDAVPIPRSGLSQLGRWMSPEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGSAVLDALGAGEFIKGLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLILGVTNPEGQKKYFAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDQQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQSNTIFTNVAETSDGGVYWEGIDQPLAPGIKLTSWKGTEWDPKDGEPCAHPNSRFCTPASQCPIIDPAWEAPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKDGRFLWPGFGENCRVLAWMFDRVQGKGGARLTPIGYVPEEAALDLRGLEAIRVSELFQVSKEFWEEEADEIHKYLEEQVNADLPYEIQSEVLALKQRISQM
What is the function of this protein?
Cytosolic phosphoenolpyruvate carboxykinase that catalyzes the reversible decarboxylation and phosphorylation of oxaloacetate (OAA) and acts as the rate-limiting enzyme in gluconeogenesis (PubMed:26792594).  Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle (By similarity).  At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity).  At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate (By similarity).  Acts as a regulator of formation and maintenance of memory CD8(+) T-cells: up-regulated in these cells, where it generates phosphoenolpyruvate, via gluconeogenesis (By similarity).  The resultant phosphoenolpyruvate flows to glycogen and pentose phosphate pathway, which is essential for memory CD8(+) T-cells homeostasis (By similarity).  In addition to the phosphoenolpyruvate carboxykinase activity, also acts as a protein kinase when phosphorylated at Ser-90: phosphorylation at Ser-90 by AKT1 reduces the binding affinity to oxaloacetate and promotes an atypical serine protein kinase activity using GTP as donor (By similarity).  The protein kinase activity regulates lipogenesis: upon phosphorylation at Ser-90, translocates to the endoplasmic reticulum and catalyzes phosphorylation of INSIG proteins (INSIG1 and INSIG2), thereby disrupting the interaction between INSIG proteins and SCAP and promoting nuclear translocation of SREBP proteins (SREBF1/SREBP1 or SREBF2/SREBP2) and subsequent transcription of downstream lipogenesis-related genes (By similarity).
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEPCK-C, Serine-protein kinase PCK1.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Note=Phosphorylation at Ser-90 promotes translocation to the endoplasmic reticulum.
Protein: MINE_BURPS
Sequence: MSILSFLLGEKKKSAAVAKERLQLIIAHERVGGRPPADYLPALQKELVAVISKYVKISNDDIRVSLERQDDLEVLEVKIEIPQA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: POTA_BACCR
Sequence: MKKIIKVEAVEKHFGNQVIIPPLSLDIKEGEFLTILGPSGCGKTTLLRMIAGFETPTKGNLLLDDERINDLPPYKRHMNLVFQHYALFPHMTVEKNICFGMKMQKVSAAEQKERAEEAMRLTQLLEFRNRKPAKLSGGQQQRVAIARAIVNNPRVLLLDEPLGALDFKLRKDLQRELKNLQRNLGITFIYVTHDQEEAMSMSDRIVVMNKGHIEQIGTPKEIYNKPKTLFVATFIGENNIVKNGEGYVAIRPENVKVRSVEEPILKEYHLGHIEDIEFVGNMEKLYVRDEKTSELLMAYQTAEEAAQWSIGDNVYVGWEQEDEVTLN
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TAAR9_MOUSE
Sequence: MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG
What is the function of this protein?
Orphan olfactory receptor specific for trace amines.
What are the official names of this protein?
Trace amine-associated receptor 9, TaR-9, Trace amine receptor 9, mTaar9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_MYCTU
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTTVNFGDYGIQALEHAYVTNRQIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPNEGVARAALTRAIHKLPIKARIITREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL36_SHIF8
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MCES_CANGA
Sequence: MSVKPEKPVWMSQEDYDRQYGTVGDGENKTAIVEKTTITTQSSSNVVVGEASKTSSDIGANKIQKRKRHDDFALEEKKRRERERRLREEQLKEHEIKLTAEKITNVNNLVREHYNERTYIANRTKRNQSPIIKLRNFNNAIKFMLIDKFTHTGDVVLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRYQSMKNLDFQAILITGDCFGESLGVAVEPFPECRFPCDVVSTQFCLHYAFETEEKARRALLNVSKSLKVGGRFFGTIPDSEFLRYKLNKIGKDVQEPKWGNQIYSIKFSNNDYHENGNEFPSPYGQMYTFWLEDAIDNVPEYVVPFETLRSLADEYGMELILQMPFNQFFVQEIPKWVNRFSPKMREGLTRSDGKYGVEGIEKEPAAYLYTVFAFKKVREHVE
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAR5_SARBU
Sequence: LSPTQDFMRF
What are the official names of this protein?
FMRFamide-5, SabFMRFamide-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_METMP
Sequence: MGKKDKRWVLQRKNDHYYNLAKRRNYRSRATYKLFQLNEKFNLIKERNVVVDLGCAPGGWLQAARDIVGEDGFIVGIDLQTVKPLPHDNIIAIKGDMTKEEILKQAKDLLPEKPDVIICDASPNISGVWDVDHVRSLELTTMALMTATKMLKKGGNFVVKVFQGDLFEKYVQLVSEYFDKAFTTKPRASRDESAEVYVIGKRFNGKKFDMNSKSPIVKLLDTKPVEEEITSPSLRKEISKEDSGLMIKRIKEMRSKKE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYME_ECO5E
Sequence: MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESELMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
What is the function of this protein?
Involved in the degradation and recycling of damaged RNA.  It is itself a target for degradation by the ATP-dependent protease Lon.
What are the official names of this protein?
Endoribonuclease SymE.
What is the protein family that this protein belongs to?
Belongs to the SymE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_DESVM
Sequence: MAFKKKFTPRRKFCRFCADKDLPLDYKRADILRDFITERGKIIARRITGTCAHHQRLLTREIKRARQMALLFYTAGHSSDVKKKSQI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PCKA_FLAJ1
Sequence: MDNNTLFAQSISLKELGIENATVRYQLSADELHAITVQSGQGVEASTGALAINTGEFTGRSPQDRFIVKDSITEDKVWWGNVNIPFAPEAFEKLYNKVKAFLSNKEVFVRDSYVCSDPNYRLNVRVVTETAWSNLFCYNMFLRPEDSELANFTPEWTVVCAPSFMADPAVDGTRQSNFAILDFTKKIALIGGTGYTGEMKKGIFSALNFILPVFENTLPMHCSANVGKDGDTAIFFGLSGTGKTTLSADPERKLIGDDEHGWTAENTVFNFEGGCYAKVINLTEENEPDIFRAIKKGALLENVVFKAGTNEVDFDDVSITQNTRVSYPITHIDNIQPGSIGHNPKNIFFLTADSFGILPPISKLTPGQAAYHFISGYTAKVAGTEAGVTEPQPNFSACFGAPFMPLHPTKYAEMLSKKMKDADVKVWLINTGWTGGAYGTGSRMKLKYTRAMITAALNGELDNVEYVNHKVFGIAKPQSCPNVPSEILNPRNTWEDKDLYDKKALELAQKFKANFAKFEEFANAEILAGAPITE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP2_LEGPC
Sequence: MMNESLTEKRNELSLSFAALGVVFGDIGTSPLYAFGQVIKYFPINDHNIYGILSLIFWSLIIIVSIKYLVIVFRADNDGEGGIIALAGVIRQKIKQPGGWLLFITLVGIGLIIGDGMLTPAISILSAVEGLESLSPNLAKYVLPVTLIILFFLFKMQSIGTGKIGVYFAPVMLVWFITIGILGFLQIIQNPKVLMAINPYYAINFFMIHKYLALFILGGVFLVMTGGEALFADLGHFGKKAIRTGWFAVALPALLLCYFGQGALVLMHTEDIKYPFFSLSPDWFLPVMIILATLATIIASQAIISAAFSILKQASLLNLIPRLKIVFTSKFEKGEVYLPLINFILALGTCSLVVIFKSSSNLADAYGIAVNLDMLITTVLVGIIAYRCWSWHAFKILIFLLILIIELAFFAGNIPKLLTGGWIPILIAFLGFVVMYTWHCGFEKLRELHHRDALMDAFIIDELNQNKISRQPGMGLYIIDPYDCEGESLLHHLRLNRIFFENMVFVSIKIENKPYIPIEDKFELIKKAEGFYLIFIHYGFTENINLPNELDEMFKRVYLPFDVIKNKLIYFIEIVFVEMTGERQKHMYLWQKHFFSLMIRNAVPDIQFYQLPYNNTIAIGTYYQF
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRK7A_DANRE
Sequence: MCDMGGLDNLVANTAYLKAQGGDDKEMKKRRRSLSLPKPEQCASLRTSLDKDFESLCEKQPIGKKLFRQYLSQGGPECTTAAEFLDDLNEWELSESAARDKARTNIINKFCKEGSKSSLTFLTGDVATKCKAVSDKDFEEVMGQVKTATKEFLKGKPFTEYQASPFFDKFLQWKEYEKQPISEKYFYEFRTLGKGGFGEVCAVQVKNTGQMYACKKLCKKRLKKKHGEKMALLEKKILERVNSLFIVSLAYAYDTKTHLCLVMSLMNGGDLKYHIYNIGEKGIEMDRIIYYTAQIATGILHLHDMDIVYRDMKPENVLLDSQGQCRLSDLGLAVEIAVGKTISQKAGTGAYMAPEILNETPYRTSVDWWALGCSIYEMVAGYTPFKGPDAKKEKVEKEEVQRRILNEEPKFEHKNFDAATIDIIKQFLKKKIDERLGCKNDDPRKHEWFKSINFARLEAGLIDPPWVPKPNVVYAKDTGDIAEFSEIKGIEFDAKDDKFFKEFSTGAVSIAWQQEMIDTGLFDELSDPNRKESSGGSDDDKKSGTCTLL
What is the function of this protein?
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
What are the official names of this protein?
Rhodopsin kinase grk7a, G protein-coupled receptor kinase 7-1, G-protein-coupled receptor kinase 7A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: FIEF_ECO24
Sequence: MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_LISIN
Sequence: MLIIRNRQELKEAILKQKKANKTIGFVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELATKLHVIKRVSVLDGADREGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGLVEDYFFPVNLRIIPTVREADGLAKSSRNVYLTETERKEAPVIHAALQLGRQLIDSGETDEAKIVQVMTDKINEQTSHEKIAYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.