PharMolix/UniProtQA huggingface dataset:
Protein: FYPP_PEA
Sequence: MDLDQWISKVKDGQHLLEDELQLLCEYVKEILIEESNVQPVNSPVTVCGDIHGQFHDLMKLFQTGGHVPETNYIFMGDFVDRGYNSLEVFTILLLLKARYPANITLLRGNHESRQLTQVYGFYDECQRKYGNANAWRYCTDVFDYLTLSAIIDGTVLCVHGGLSPDIRTIDQIRVIERNCEIPHEGPFCDLMWSDPEDIETWAVSPRGAGWLFGSRVTSEFNHINNLDLVCRAHQLVQEGLKYMFQDKGLVTVWSAPNYCYRCGNVASILSFNENMEREVKFFTETEENNQMRGPRTGVPYFL
What is the function of this protein?
Catalytic subunit of protein phosphatase 6 (PP6) (Probable).  Dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms.  Plays a major role in the photoperiodic control of flowering time in long days by modulating phytochrome signals in flowering time control.
What are the official names of this protein?
Phytochrome-associated serine/threonine-protein phosphatase, PsFyPP.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_HAEIN
Sequence: MAGAKEIKTKIASVQSTQKITKAMEMVATSKMRKTQDRMAASRPYSETIRNVISHVSKASIGYKHPFLVEREVKKIGILVISTDRGMCGGLNVNLFKTTLNQIKNWKEQNISTDLGLIGSKGISFFRSFGFNIKGQLSGLGDTPALEELIGVANTMFDAYRNGEIDAVYIAYNKFVNTMSQKPVVQQLVPLPESKDDHLNERQQTWDYLYEPEPKVLLDSLLVRYLESQIYQAVVDNVASEQAARMVAMKAATDNAGNLINDLRLVYNKARQASITNELNEIVAGAAAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MOAB_METJA
Sequence: MHKRIKNIKYAVVTVSDSRYNDLIKGKEVDDKSGKLLKKELNAKVYTIIPDNKNMIKGIVEHIVEFFDVDCIVFTGGTGIAERDVTVEALKEIIEKELDGFKIIFQKLSYEEVGFSAMLSRAMAGIYKGKIIYALPGSVNACRTALKIIKEETGHILGHLREG
What is the function of this protein?
Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
What are the official names of this protein?
Probable molybdopterin adenylyltransferase, MPT adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: HTPX_THEYD
Sequence: MHTLKTLVLMVFLSVFFIFVGSLIGGKQGATFALIMALGMNFFAYFFSHKIVLAMYGAKEVSEAEAPELYNIVRRLAQKAELPMPKVYIIDSEQPNAFATGRSPKHGVVAVTTGIMRILSREELEGVIGHELAHIKHRDILISTIAATIAGAISYLAQMAMWANIFGGRHDDEEGGGHPIVALLMMIIAPLIAMIIQLAISRSREYAADEDGARIAGNPLYLSNALRKLHYASQAIPMDANPGTAHMFIVNPLSGKTLMKLFSTHPPIDERIARLEAMARRY
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_CHLL2
Sequence: MRAVVQRVLSASVAAGSSRHSEIGRGLLVLLGVAQGDTELEAEWMSRKIVQLRIFDDAAGRMNLPVRDTGGDILLVSQFTLYGDASRGNRPGFSGSADFEKARPLYEKAVRSIEQHLGKPVMTGWYGEAMQVALINDGPVTLILDTPQRL
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG36_ALHV1
Sequence: MEVNRLAYLTAMGSLRPPSPNGDWSKPQDAPHKSVIDMMASGVSHIKVLKVDIDAQHLCVCLPHNMLTCCHPAVDMENLLGSGSFGKVYASGPGICAKVFTSAEAFYHETVMMDLVALARSYNCDDFKSVCLQFYLSACVTCKTIWYPRFSQSLHTFKDFTVDHLHDLDREFKGLTDAVFFLNQKCGLFHGDICPSNILVETFKGPGSGIKSLILTDLGTAAIHAGNTFKSLSINNPQDDSVIYNAQIYLSPFLVCKDYVKPLCVLRRCYLLRHHAQDVDVEEITDTVVGQNMALKIDCSTLLQVLLLVLARVMEQPNSLTYESWLREIEDDSSDAYFLLLLGPKLVLLTHLSQLWEINFDVGVNTQGVLSRGQLPHPHTRLLKECCQLFREEFDAVVKEEVLIKLGQGVLKNIIFELLQFDYFEIHGRQPQHGLFAQSHAARADSEHGNWRTS
What are the official names of this protein?
Putative tyrosine kinase 36.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Protein: SFSA_SYNE7
Sequence: MPQRLYTYPPLLRGRLLQRYKRFFADIELDSGETITAHCPNTGPMTGVCQMGNLVYVSKSDNPKRKLAYTWELIEVTDNEPTWVGVNTGLPNRVVQALLEQRCLPVLGDYGEVQREVPYGENSRIDFRLTGDRPIYVEVKNTTWTAGRLALFPDTVTTRGQKHLRELTAILLEARAVMLYFINRGDCTAFAPGDSADPTYGQLLRTGIAAGLEVYPCQFQISPEGIDFLGVAPLQL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RL31_THEKO
Sequence: MPIKPGEEVIFVVPINKIKKRVPRWKRAPRAARFVREWIARHAKADEVIIGTDVNEKIWERGAEKPPGKLRVKVVVEESEGKRIARVSLA
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: YOAE_ECO57
Sequence: MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKATTELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAAVVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPIPEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRARGSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQQALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIVKEQPAHDEDE
What are the official names of this protein?
UPF0053 inner membrane protein YoaE.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_LACPL
Sequence: MTKIIDGKAVAKKVNAQTATAVAELAAQGIQPGIAVIIVGDDAASQIYVRNKNRKATKLGMHSVVRQLPATTSQDELLAIIAAYNADDSIHGILVQSPLPAQINEPLITMAIDPKKDVDGFHPTNVGKLITNFPGNYPVANTPRGIMTMLADYGVDPAGKTAVVIGRSTIVGKPMAALLTNANATVTIAHSKTADLKAVARTADILVVATGIAHLITGADIKPGATVIDVGMDRDENGKLVGDVDFDSAQGIAGLITPVPGGVGPMTIATLMQTTVELAKWSDVSE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VP4_ROTW3
Sequence: MASLIYRQLLANSYAVDLSDEIQSVGSEKNQRVTVNPGPFAQTVYAPVNWGPGEVNDSTVVQPVLDGPYQPASFDLPVGNWMLLAPTGPGVVVEGTDNSGRWLSVILIEPGVTSETRTYTMFGSSKQVLVSNASDTKWKFVEMMKTAIDGDYAEWGTLLSDTKLYGMMKYGKRLFIYEGETPNATTKRYIVTNYASVEVRPYSDFYIISRSQESACTEYINNGLPPIQNTRNVVPVAIVSRSIKPREVQANEDIVVSKTSLWKEMQYNRDIIIRFKFDNSIIKSGGLGYKWAEISFKAANYQYNYMRDGEDVTAHTTCSVNGVNDFSFNGGSLPTDFAISRYEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNDVMCSGGHYSFALPAGQWPVMKGGAVTLHTAGVTLSTQFTDYVSLNSLRFRFRLAAEEPSFTITRTRVSKLYGIPAANPNGGREYYEVAGRFSLISLVPSNDDYQTPIMNSVTVRQYLERHLNELREEFNNLSQEIAVSQLIDLAMLPLDMFSMFSGIESTVNAAKSMATNVMRKFKSSKLASSVSMLRDSLSDGASSIARSTSIRSIGSTASAWANISERTQDAVNEVATISSQVSQISGKLRLKEITTQTEGMNFDDVSGAVLKAKIDRSIQVDQNALPDVITEASEKFIRNRAYRVIDGDEAFEAGTDGRFFAYKVETLEEMPFNIEKFADLVTNSPVISAIIDFKTLKNLNDNYGITREQAFNLLRSNPKVLRGFIDQNNPIIKNRIEQLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: PNCB_PSE14
Sequence: MSESAFSNRIVQSLLDTDFYKLTMMQAVLHNYPNVDVEWEFRCRNGEDLRPYLDEIRHQIELLCELSLSPEHLAFLERITFIKPDFLRFLGLFRFNTRYVKTSIENDELCIRLHGPWLHVILFEVPLLAIVSEVRNRHRYPDTLLSQARDRLYDKFEWLTTHATADELAELKVADFGTRRRFSYRVQEEMLGVLKNDFPGQFVGTSNVHLARQLDLKPLGTMAHEWIMAHQQLGPRLIDSQIAALDCWVREYRGLLGIALTDCITTDAFLNDFDLYFAKLFDGLRHDSGDPVKWAEKCISHYQKLGIDPMSKTLVFSDGLNLPKALDIFRALRGRINVSFGIGTNLTADIPGIAPMNMVLKMTACAGQAVAKISDEPGKTQCKDPNFVAYLRHVFKVPDLPSPEKPA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: FNX1_SCHPO
Sequence: MVDQVNLATEQTSLLYPEVSRKKEELSVNKWTILPALWVGGFLSALDMTIVASLYPVIGSEFKLMNNASYIVTAYLITNTAFQPLYGRLSDIFGRRPTVVFANAAFTLGTFWCGISRSLPELCMARALAGIGGGGLGTMSSIISSDIVSLRERGTWQGITNIVWGIGGSLGGPLGGLIAQRWGWRTAFHFQVPMGILSTILVAWRVRVKPTVRNSNASLLSRIDYLGSFLLVTGITALVVTFNMGGDAFPWVSPVIITLLVSSVLILFAFYWVEKNIAVEPIAPVEILSQPTPLNVCLGNFFNAFCSFVIVYELPLFFETTLLMPSSEAGVRIFPYVISTSVGSLCSGLYMKKTGRYRNLVIAGFFFMLMGIVSFAVLTSFGHRTPLILISLCLAMTGCSYGMNLTSTLIAIISSLAPEEQAVATGLSYLFRATGSVIGISLSQTTTLSILMKQLASNLKDDPDKDDLIRRLRESISIIPNLPKDIQKLVIKSYATAFTWTFALVAIIAFAGFWCSLRIKQFYLHTSVDRS
What is the function of this protein?
Efflux transporter.  Confers resistance to a variety of toxic compounds.
What are the official names of this protein?
Multidrug resistance protein fnx1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: HCD2_RAT
Sequence: MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP
What is the function of this protein?
In addition to mitochondrial dehydrogenase activity, moonlights as a component of mitochondrial ribonuclease P, a complex that cleaves tRNA molecules in their 5'-ends.  Together with TRMT10C/MRPP1, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity.  The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; HSD17B10/MRPP2 acting as a non-catalytic subunit.  The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme.  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
What are the official names of this protein?
3-hydroxyacyl-CoA dehydrogenase type-2, 17-beta-estradiol 17-dehydrogenase, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, MHBD, 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)), 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3alpha(or 20beta)-hydroxysteroid dehydrogenase, 7-alpha-hydroxysteroid dehydrogenase, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, Mitochondrial ribonuclease P protein 2, Mitochondrial RNase P protein 2, Short chain dehydrogenase/reductase family 5C member 1, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein: RS10_NITEU
Sequence: MQNQKIRIRLKAFDYRLIDKSAIEIVETAKRTGAVVKGPVPLPTRIERFDVLRSPHVNKTSRDQFEIRTHLRLMDIIDPTDKTVDALMKLDLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GCS2_CHRVO
Sequence: MLEFNQSQPLTLGVELELMILNRRDYNLTRGSDDLLLQINRKPHGYDIKPEITQGMIEIGTAVHSDVNAMLDELLAIRTLLVDSAHKLNLGLAGGGAHPFQHWEDQRIYPKERYKLVSELYGYLAKQFTVYGQHIHIGCPDGDAAVRLTHYLARYIPHFIALSASSPFYQGVDTSFQTSRLTSVNAFPLSGCMPVVDSWDAFNAYFERMEALGIVASMKDFYWDIRPKPEYGTVEIRICDTPLSVETPVLLAAYAQMLARRCFEESWNDICPEPYLTYSYNRFQACRFGFDGVMVDARSKSQLGLQEDLLDTLRALEPHAEALGSQHQLAALRQRALKCHSDSRWLRQIFEQSGSLSEVVRRQSEHWMYAEPGVGVN
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: EO_BOMMO
Sequence: MVCGLTSCLGSGAAGGLFSSAVQFFAATQCLVGETWPKDSVLQNGSRYDFIIVGAGTAGSALAARLSEVANFSVLLLEAGGDPPIEAIIPAFRETLKASSVDWNFTSVENNITSQALKRGIEQQPRGKMLGGSGSLNHMVYARGFPSDYHEWASIAGETWNWTNVLKYFMKTEHMTDTNIVNNPELMVYHGRGGAIEVSGTNEVMFSIKKFLQAFEELGFKTVPDMTYPNSIGAGCFSHTIRNGERDSSLRALLNNANSTSLHILKDTFVTKIIIENGTAIGIEAVKDDKTFLFYADREVILSAGTFNTPKLLMLSGVGRSEHLRSLGIDVVADLPVGSNLHDHAMVLAFLVADNGTCVSDEAENSMEAIKYLYDRTGFLAKADNMAAYLPLSSSEPTVPEFALYPTCIPQFSPFRSGCLTLGLNEDLCTELHNLNQEYELVTIAAVLLKPKSRGKVELNSINPFDDPLIYAGTFSEEQDLDHFPRLIKMAWSIADTNYFRSKNARVIKPWVEACSNLTESAWIKCMSRAMVTSAWHSVGTAAMGTVVDGDLKVLGINGLRVVDASVMPKIIRGNTNAPVVMIAEIAADLIKEHYSVSRTGTNLNNMTIGNLTASSMPNISQPNINLADVIENNDMINSSLIEVEITNVEIITTTDRQSDIDDTVNVA
What is the function of this protein?
Involved in the inactivation of ecdysteroid molting hormones by converting ecdysteroids into 3-dehydroecdysteroids.
What are the official names of this protein?
Ecdysone oxidase, BmEO.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: GATA_DESPS
Sequence: MKAYELSIEEAAAKLRAGDISSVELTQSCLQRIGDVEDRVKGFITVDEEGALAQAKAADKALQNGETNPLCGIPMSIKDLLAVKDLPMTCGSKMLEKFIAPYNATIVDKLQGAGAVNLGKVTMDEFAMGSTSETCAFGVPQNPWKEGYVAGGSSGGSAVTVAAQECFFSIGTDTGGSIRQPAALCGVVGMKPTYGRVSRYGLTAFASSLDQAGPLCRTVADTALVMNSICGYDPMDSTSINQEVPDYTASLVEGVKGLRIGIPKEYFAKGLDSEVEKVVRNAIAVLASAGAEIVDVSLPHTEYCVAVYYLIAPAEASTNLSRYDGALYGYRDLESKTLEDMYKDTRSAGFGDEVKKRILIGTYALSSGYYDAYYKKASQVRTLIIEDFKNAYRSCDVLLSPVTPTPAWKLGAKSDDPLAIYLSDIMTVSANLAGIPGMSVPGGFTEDGLPVGIQLQGSHFQEEILLKVAYNLEKLLAIQPGKLDF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: STIM2_MOUSE
Sequence: MLLFGLLVAGVADGCDLVPRHLRGRRASGSAGAAASPSAAAAGERQALLTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVDESDEFIREDMKYKDATNKHSHLHREDKHITVEDLWKQWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHETSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTISIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRTVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVPQFPGTVAKPAGSLARSSSLCRSRRSIVPSSPQSQRAQLPAHAPLAAHPRHPHHPQHPQHSLPSPDPDILSVSSCPALYRNEEEEEAIYFTAEKQWEVPDTASECDSLNSSSGRKPSPPSSLEMYQTLSSRKISRDELSLEDSSRGESPVTADVSRGSPECVGLTETKSMIFSPASRVYNGILEKSCSMHQLSSGIPVPHPRHTSCSSAGNDSKPVQEASNVSRVSSIPHDLCHNGEKSKKPSKIKSLFKKKSK
What is the function of this protein?
Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores.  Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx.  Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations.  Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3.  May inhibit STIM1-mediated Ca(2+) influx (By similarity).
What are the official names of this protein?
Stromal interaction molecule 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Dynamically translocates from a uniform endoplasmic reticulum distribution to punctual endoplasmic reticulum-plasma membrane junctions in response to decrease in endoplasmic reticulum Ca(2+) concentration.
Protein: ADD_SHEB2
Sequence: MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVGVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGILSRSFGQAACTQELEGLLAHKQHLVAMDLAGDEMGFPGELFNDHFKRVRDADLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPKLMEYLAKHRIGIESCPTSNLHTSTVASYAEHPFRTFMDAGVLINLNTDDPGVSAIDINHEYRIAKAELKLTDAELAQVQRNGVEMAFLSDSDRKALYAAKV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: AROA_SYNP6
Sequence: MAQPFVLLPTEDSHQTLRIQPPSTGIGLRGRIRVPGDKSISHRALMLGAIASGETTIEGLLLGEDPLSTAACFRAMGAEISELNSELVRVKGIGLQNLQEPLDVLNAGNSGTTIRLMMGLLAGQRDRFFCVTGDESLRSRPMARVIQPLSQMGAEIRGRQGNTRAPLAISGRSLQPIRYVSPIASAQVKSSILLAGLTCEGQTTVVEPALSRDHSERMFRAFGAKLTVNPEEISVTVEGPAELTGQPVVVPGDISSAAFWLVAAAIVPDSDLLIENVGVNPTRTGILEALQQMEAQITLENERIVAGEPVADLRVRSSNLQAIEIGGSLIPRLIDEVPILAVAAAFAKGTTIIRDAEELRVKESDRIAVMASELGRMGATISERPDGLEITGGAALTGATVDSYTDHRIAMSLAIAALQAKGQTQIQQAEAAAVSYPDFVPTLQQLLG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRTM1_HUMAN
Sequence: MKGELLLFSSVIVLLQVVCSCPDKCYCQSSTNFVDCSQQGLAEIPSHLPPQTRTLHLQDNQIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHELYQPCPLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECELKPKPRPANLRHAIATVIITGVVCGIVCLMMLAAAIYGCTYAAITAQYHGGPLAQTNDPGKVEEKERFDSSPA
What are the official names of this protein?
Leucine-rich repeat and transmembrane domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYE_ECODH
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_COXB2
Sequence: MIKQRTLKNVVRATGVGVHTGEKVYLTLRPAPPNTGIIFCRTDLDPVVQIPARVNYIGDTSLSTCLTKGDVRIATVEHLLSALAGVGVDNLYIDLTSPELPIMDGSAGPFVFLIQSAGIEEQNAPKEFIRIKQRVKIEEADKSVMVEPYNGFKISFGIDFDHPLFNEHNQNATLDFSSTSYVKEVSRARTFGFLSDYEFIRKNNLALGASLDNALVLDEYKILNQDGLRYPDEFVKHKILDVIGDLYLLGRSLIGSFSGVKSGHTLNSQLLKQLLATKSAWEIVTFKDPSELPFAYTPVAMTA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: GREM1_CHICK
Sequence: MVRTLYAIGAVFLLTGFLLPTAEGRKRNRGSQGAIPPPDKDQPNDSEQMQTQQQSGSRHRERGKGTSMPAEEVLESSQEALHITERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHVRKEEGSFQSCSFCKPKKFTTMTVTLNCPELQPPRKKKRITRVKECRCISIDLD
What is the function of this protein?
Cytokine that may play a role in the development of the medial pallium and during optic nerve and pecten development by modulating BMP signaling.
What are the official names of this protein?
Gremlin-1.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_PELPB
Sequence: MHNPLSILLRPAALGYRVIVQLRNTLFDRQLLPAWKSPVPIVSIGNLSVGGTGKTPLVDWVVKYYLSIGCKPAIISRGYRRESKGVQLVSDGQKVLLSSSESGDETAMLAWNNPDAIVIVAKKRKEAVKYLVKHFAARMPSVIILDDAFQHRQIQRELNIAIINVSEPFLKARMLPEGRMREPLKNLSRADLIVLNKIDDPEKADAIVRKIKERGTPLIKARVAIAELVCFSGAFISSEEAPPLTSISALAFAGISSPQSFLDSLGKEGVTIAAHRFFYDHEPYSAKKLTEIFREAESKGLSLITTEKDYFRMLGHPELIRIITARPCYYLKIKTDIFEGKEILQSMLRKAVAMK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.