PharMolix/UniProtQA huggingface dataset:
Protein: CSPLB_MAIZE
Sequence: MAAAARVSEVKAEGLLRGACTALAAAAALLVGLSTQTETVLLVRKKATVKDVQALWVLAMAAAAAAGYHLLQLLKCLYLGRVGGARPCRRSSRALAWTCLLLDKACAYTTFATTVAAAQACVVALDGAHALQWTKLCNIYTRFCEQVAGSLVLGMLAAVGTAVLSAASARNVFRHYASLETYAAH
What are the official names of this protein?
CASP-like protein 2C2, ZmCASPL2C2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_AQUAE
Sequence: MVKVKICGITNLEDALFCAKEGADYIGVITYPKSPRYTSKEKRLEIIKALEGLNVKKVAVVVNEPYEFIKELLDEGFDLIQLHGDEDIELGKRVGLDKVIKVFRVKEEIPKVGEWEKAYAILLDTFSKEAYGGTGKTFNWEIAKKLVEEGHKVFLSGGLNPENVKEGIEFVKPYGVDVSSGVEKEKGKKDFKKVREFIKRTKSE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: DUT_FRATF
Sequence: MKVELKILNKELIKELPGYATEGSAAIDLRACISESIYLKSGECKLIATGIAINIANPNYAAMILPRSGLGHKKGLVLGNGTGLIDSDYQGELMVSCFNRSQETIEIEPLMRFAQLVIVPVVQANFEIVEDFSQQSVRATGGFGHTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y586_CHLTB
Sequence: MGSGYAKKKKEAKLMERQFMEMEASLEQKRFSGEAGNGLVSVTINGKCDLVDVRIKPDCLDPEDPEVVADLFRAAFKAAKAALDSEMSAMQMGMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CTLon_0586.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL15_DEIGD
Sequence: MKLHDLTPAPGSRKPKKRVGRGPGGTDKTAGRGHKGQKSRSGAGKGPFFEGGRSTLISRLPKRGFNNVGTTYEVVNLAQLARVEGDTLDRTALERAGLVRRKDRPVKLLARGQVTRAVTVQVDAASEAAIRAVEAAGGRVVVTGADRQNAEQAG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HTPX1_METMA
Sequence: MKNMLKTTVLLAALTGLLVIIGDYFGGTGGMIIAFLFAVVLNFGSYWYSDKIVLKMYRAKEVSPAEAPNLHRIVDGLVMKAGIPKPKVYIVQSGMPNAFATGRDPKHAAVAATTGILELLSYEEMEGVLAHELAHVKNRDTLISAIAATLAGVVTMLAHWAQWAAIFGGFGGRDDDGNGGIVGLIAMAIVAPIAATLIQLAISRSREFAADEEGARISRKPWALADALEKLEYGNSHYRARVSDVQAKESSAHMFIVNPLKGGAVQSLFRTHPVTDERVRRLRAMKF
What are the official names of this protein?
Protease HtpX homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CNKR2_MOUSE
Sequence: MALIMEPVSKWSPSQVVDWMKGLDDCLQQYIKNFEREKISGDQLLRITHQELEDLGVSRIGHQELILEAVDLLCALNYGLETENLKTLSHKLNASAKNLQNFITGRRRSGHYDGRTSRKLPNDFLTSVVDLIGAAKSLLAWLDRSPFAAVTDYSVTRNNVIQLCLELTTIVQQDCTVYETENKILHVCKTLSGVCDHIISLSSDPLVSQSAHLEVIQLANIKPSEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALREDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHMVGKPVHKGSESPNSFLDQEYRKRFNIVEEDTVLYCYEYEKGRSSSQGRRESTPTYGKLRPISMPVEYNWVGDYEDPNKMKRDSRRENSLLRYMSNEKIAQEEYMFQRNSKKDTGKKSKKKGDKSNSPAHYSLLPSLQMDALRQDIMGTPVPETTLYHTFQQSSLQHKSKKKNKGAISGKSKRRISCKDLGRGDCEGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKIDRASECRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQEQDYWSESDKEEADTPSTPKQDSPPPPYDTYPRPPSMSCASPYVEAKHSRLSSTETSQSQSSHEEFRQEVTGSSAVSPIRKTASQRRSWQDLIETPLTSSGLHYLQTLPLEDSVFSDSAAISPEHRRQSTLPTQKCHLQDHYGPYPLAESERMQVLNGNGGKPRSFTLPRDSGFNHCCLNTPVSACDPQDDIQPPEVEEEEEEEEEEAAGENVGEKNENREEKLGDSLQDLYRALEEASLSPLGEHRISTKMEYKLSFIKRCNDPVMNEKLHRLRILKSTLKAREGEVAIIDKVLDNPDLTSKEFQQWKQMYLDLFLDICQSTTSNDPLSISSEVDVLTSSLTHTHSYIETHV
What is the function of this protein?
May function as an adapter protein or regulator of Ras signaling pathways.
What are the official names of this protein?
Connector enhancer of kinase suppressor of ras 2, Connector enhancer of KSR 2, CNK homolog protein 2, CNK2.
What is the protein family that this protein belongs to?
Belongs to the CNKSR family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: APAH_PSE14
Sequence: MAVYAVGDLQGCLEPLQCLLEHVHFNPEHDRLWLVGDLVNRGPQSLETLRYLYGLRESLVCVLGNHDLHLLAVARKHELLKKGDTLREILEAPDRDELLGWVRRQKLMHYDAERNVAMVHAGIAPQWSLKKALKHAAEVEQALQEDQLYGAFLDGMYGNEPAKWDNDLQGVTRLRVITNYFTRMRFCTSDGKLDLKSKEGVETAIPGYAPWFSHPKRKTRELKIIFGHWAALEGRCDEPGVFALDSGCVWGGSMTLLNVDTLERHQCNCDAVGHAANGLVKSAQAGTATNPQAQEPRQ
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: CARP_MYTED
Sequence: AMPMLRL
What is the function of this protein?
This peptide exhibits both potentiating (contraction) and inhibitory (relaxation) effects on the anterior byssus retractor muscle.
What are the official names of this protein?
Catch-relaxing peptide, CARP.
Protein: Y572_AZOSB
Sequence: MLMTTTPTLEGKPVQQYLGVVTGEAIIGANIFKDLFASIRNIVGGRAGAYERSLADAREVAMAEMAEQALKLGANAVIGIDIDYEVLGQDNGMLMVCVSGTAVITA
What are the official names of this protein?
UPF0145 protein azo0572.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: OPGC_SALG2
Sequence: MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFPKRQETSKPRPAAISLVRLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FRG1_XENLA
Sequence: MAEYSKVKSTKLMLKGIKNKSKKNKDKKRKREESDEDKLDIAGNWWSVKNFGEISGTVAIEMDKGAYIHALDNGLFTIGAPHKDDDDGPSPPEQFTAIKLSDSRVALKSGYGKYLGINSDGLVIGRSDAIGAREQWEPVFDTGKMALLASNSCFVGCNEEGDLVAQSKTAGEGEMIKIRSCAEREAKRDDDIPNEDKGNVKQCEINYVYV
What is the function of this protein?
Binds to mRNA in a sequence-independent manner.  May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits.  May be involved in mRNA transport.  May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B (By similarity).
What are the official names of this protein?
Protein FRG1.
What is the protein family that this protein belongs to?
Belongs to the FRG1 family.
What are the subcellular locations of this protein?
Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line.
Protein: PRAF3_RAT
Sequence: MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGIIVVLVFTGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISMFGGVMVFVFGITFPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDSINKFADYISKARE
What is the function of this protein?
Regulates intracellular concentrations of taurine and glutamate (Ref. 5).  Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner (PubMed:11242046).  Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (PubMed:19720795).
What are the official names of this protein?
PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, Prenylated Rab acceptor protein 2, Protein JWa.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton. Note=Also exists as a soluble form in the cytoplasm (PubMed:11242046). Associated with microtubules (Ref.5).
Protein: CCL2_CAVPO
Sequence: MQRSSVLLCLLVIEATFCSLLMAQPDGVNTPTCCYTFNKQIPLKRVKGYERITSSRCPQEAVIFRTLKNKEVCADPTQKWVQDYIAKLDQRTQQKQNSTAPQTSKPLNIRFTTQDPKNRS
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RP1_HUMAN
Sequence: MSDTPSTGFSIIHPTSSEGQVPPPRHLSLTHPVVAKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPPHPVAVAAPGMPRPPRSLVVFRNGDPKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPARLPGISQRVYPKGNAKSESRKISTHMSSSSRSQIYSVSSEKTHNNDCYLDYSFVPEKYLALEKNDSQNLPIYPSEDDIEKSIIFNQDGTMTVEMKVRFRIKEEETIKWTTTVSKTGPSNNDEKSEMSFPGRTESRSSGLKLAACSFSADVSPMERSSNQEGSLAEEINIQMTDQVAETCSSASWENATVDTDIIQGTQDQAKHRFYRPPTPGLRRVRQKKSVIGSVTLVSETEVQEKMIGQFSYSEERESGENKSEYHMFTHSCSKMSSVSNKPVLVQINNNDQMEESSLERKKENSLLKSSAISAGVIEITSQKMLEMSHNNGLPSTISNNSIVEEDVVDCVVLDNKTGIKNFKTYGNTNDRFSPISADATHFSSNNSGTDKNISEAPASEASSTVTARIDRLINEFAQCGLTKLPKNEKKILSSVASKKKKKSRQQAINSRYQDGQLATKGILNKNERINTKGRITKEMIVQDSDSPLKGGILCEEDLQKSDTVIESNTFCSKSNLNSTISKNFHRNKLNTTQNSKVQGLLTKRKSRSLNKISLGAPKKREIGQRDKVFPHNESKYCKSTFENKSLFHVFNILEQKPKDFYAPQSQAEVASGYLRGMAKKSLVSKVTDSHITLKSQKKRKGDKVKASAILSKQHATTRANSLASLKKPDFPEAIAHHSIQNYIQSWLQNINPYPTLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNSGKISNFVMESNKHITKIAGLTGDNLCKEGDKSFIANDTGEEDLHETQVGSLNDAYLVPLHEHCTLSQSAINDHNTKSHIAAEKSGPEKKLVYQEINLARKRQSVEAAIQVDPIEEETPKDLLPVLMLHQLQASVPGIHKTQNGVVQMPGSLAGVPFHSAICNSSTNLLLAWLLVLNLKGSMNSFCQVDAHKATNKSSETLALLEILKHIAITEEADDLKAAVANLVESTTSHFGLSEKEQDMVPIDLSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCEMCTVNKAYSPKETCNPSDTFFPSDGYGVDQTSMNKACFLGEVCSLTDTVFSDKACAQKENHTYEGACPIDETYVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSHQNVSNLSSCGLCLSEKEAELDKKHSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSERNISELESFEELENHDTDIFNTVVNGGEQATEELIQEEVEASKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKETNEGETKMVKMMVKTMETGSYSESSPDLKKCIKSPVTSDWSDYRPDSDSEQPYKTSSDDPNDSGELTQEKEYNIGFVKRAIEKLYGKADIIKPSFFPGSTRKSQVCPYNSVEFQCSRKASLYDSEGQSFGSSEQVSSSSSMLQEFQEERQDKCDVSAVRDNYCRGDIVEPGTKQNDDSRILTDIEEGVLIDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDELSSSELEELTQPLELKCNYFNMPHGSDSEPFHEDLLDVRNETCAKERIANHHTEEKGSHQSERVCTSVTHSFISAGNKVYPVSDDAIKNQPLPGSNMIHGTLQEADSLDKLYALCGQHCPILTVIIQPMNEEDRGFAYRKESDIENFLGFYLWMKIHPYLLQTDKNVFREENNKASMRQNLIDNAIGDIFDQFYFSNTFDLMGKRRKQKRINFLGLEEEGNLKKFQPDLKERFCMNFLHTSLLVVGNVDSNTQDLSGQTNEIFKAVDENNNLLNNRFQGSRTNLNQVVRENINCHYFFEMLGQACLLDICQVETSLNISNRNILELCMFEGENLFIWEEEDILNLTDLESSREQEDL
What is the function of this protein?
Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors.  Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme (By similarity).
What are the official names of this protein?
Oxygen-regulated protein 1, Retinitis pigmentosa 1 protein, Retinitis pigmentosa RP1 protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, photoreceptor outer segment. Note=Specifically localized in the connecting cilia of rod and cone photoreceptors.
Protein: ACCA_COLP3
Sequence: MSLNFLDFEQPIAELDAKIEELQLVNNGQELDLDIEDQISQLREKNKEQTKKIFSNLDAWQTARVARHPQRPYSLDYIPRIFTEFDELAGDRAYANDNAIVGGTARLDGKPVMIIGHQKGRSTAEKVKRNFGMPRPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLKVMARLSVPIICTVIGEGGSGGALAIGVGDRVNMLQYATYSVISPEGCASILWKTAEKAPTAAAAMGITAQRIKELDLINSIVEEPLGGAHRDMDVMAAHLKQAIKKDLSELEGLSKDELIEQRYDRLMSFGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3487_STRM5
Sequence: MPSFDVVSEVDTHELTNAIDQANRELATRFDFKGVDAKFEREGDVINQTAPTEFQLKQMNDILRARLAARGIDVLSLEFGDIETNLAQARQKITVKQGIEQKIAKKIAAALKDAKLKVESQINGDKLRVQGKKRDDLQDAIAVLKAGKFELPLQFNNFRD
What are the official names of this protein?
UPF0234 protein Smal_3487.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ADA22_HUMAN
Sequence: MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQASFQVDAFGTSFILDVVLNHDLLSSEYIERHIEHGGKTVEVKGGEHCYYQGHIRGNPDSFVALSTCHGLHGMFYDGNHTYLIEPEENDTTQEDFHFHSVYKSRLFEFSLDDLPSEFQQVNITPSKFILKPRPKRSKRQLRRYPRNVEEETKYIELMIVNDHLMFKKHRLSVVHTNTYAKSVVNMADLIYKDQLKTRIVLVAMETWATDNKFAISENPLITLREFMKYRRDFIKEKSDAVHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECVLEGAECCKKCTLTQDSQCSDGLCCKKCKFQPMGTVCREAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRDRQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCGKDKDTWIQCNKRDVLCGYLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPVASFNFSTCLSSKEGTICSGNGVCSNELKCVCNRHWIGSDCNTYFPHNDDAKTGITLSGNGVAGTNIIIGIIAGTILVLALILGITAWGYKNYREQRQLPQGDYVKKPGDGDSFYSDIPPGVSTNSASSSKKRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQGNLGGNKKKIRGKRFRPRSNSTETLSPAKSPSSSTGSIASSRKYPYPMPPLPDEDKKVNRQSARLWETSI
What is the function of this protein?
Probable ligand for integrin in the brain.  This is a non catalytic metalloprotease-like protein (PubMed:19692335).  Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation.  Neuronal receptor for LGI1.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 22, ADAM 22, Metalloproteinase-disintegrin ADAM22-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon.
Protein: VMP1_HUMAN
Sequence: MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQSIVVSFLLLLAVLIATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLNSEEKTK
What is the function of this protein?
(Microbial infection) Host factor required for infection by all flaviviruses tested such as Zika virus and Yellow fever virus (PubMed:33338421).  Probably required post-entry of the virus to facilitate the ER membrane remodeling necessary to form replication organelles (PubMed:33338421).
What are the official names of this protein?
Vacuole membrane protein 1, Transmembrane protein 49.
What is the protein family that this protein belongs to?
Belongs to the VMP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MDH_PARP8
Sequence: MAKPAKRVAVTGAAGQIGYSLLFRIANGDMLGKDQPVILQLLDLPQAQAAVKGVVMELEDCAFPLLAGVVVTDDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGKALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPKKNFTAMLRLDHNRALSQLAAKSGKPVSSIEKLVVWGNHSPTMYPDFRVATAEGQDLTKLINDEEWNRNTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGTNGKWVTMGIPSDGSYGIPEDIVYGVAVTCENGEYKRVEGLQIDAFSREKMDNTLNELLEERDGVQHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: VP6_ROTHD
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPTRNWSFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSESLRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANIQQFEHIVQLRRVLTTATITLLPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIVARNFDTIRLSFQLMRPPNMTPSVAALFPNAQPFEHHATVGLTLRIESAVCESVLADASETMLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLVK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: YBEY_STRPN
Sequence: MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVTNERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGELFISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1676_SULIN
Sequence: MVKVMVVAEVRPSEDVNKVLSAISNFFDFEKTNTRKEGIIDILVLEARTLKSLLKFHRVLRNERILDSARKYLMKGIEGNTIAFMIHKQAAAVGVLSFVDSDKESPLGAIKFYIEYQNPKEVVDWLAPRTAHGVPLWDNPIPPDV
What are the official names of this protein?
UPF0201 protein YN1551_1676.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: RPPH_BRUA2
Sequence: MSEHKGPTGAMVDPESLPYRPCVGLMVLNKAGLVWAGRRIVIPGDEMDGATQLWQMPQGGIDKGEDPAQAALRELYEETGMTSVSLLEEASDWINYDLPPHLMGLALKGKYRGQTQKWFAYRFEGDESEIAINPPPGGHTAEFDCWEWKPMADLPNLIVPFKRKVYEQVVATFRHLAA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PDXB_YERPG
Sequence: MKILVDENMPYAEELFRRLGDVQAVPGRPIPRDALVDADALMVRSVTKVNEALLHGTSIGFVGTATAGTDHVDDTWLRQQGIGFSAAPGCNAIAVVEYVFSALMMMAERDGFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLCDPPRADRGDNEAFWPLEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGRILINACRGAVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVDIGTPHIAGYTLEGKARGTTQVFEAFSQHLGQPQSVELASLLPVPEFSHLRLNGELDEGKLKRLMHLVYDVRRDDAPLRHVAGLPGEFDRLRKHYQERREWSSLCVQCDDATSAGLLQQLGFTTQLL
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1048_GEOSL
Sequence: MTNLCPCGTGKSFGECCEPLVTGARAALTAEELMRSRYTAYTRAEIGYIHDTTHPDHRADFDEKGTREWAESSQWEGLEILATAGGGPADTEGRVEFIARYRDTGGRRTHHELAEFRKVDDAWYFTDGYGIKPQPAVSTKIGRNDPCTCGSGKKYKKCCGA
What are the official names of this protein?
UPF0225 protein GSU1048.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: RECO_CHLP8
Sequence: MIVKTRAVVLRDIKYRDQSKICLLLTREYGQVSVILKGGRSAKSKTGMLFSPGNLIDAVLYKKGNRDLQLASDASLVKSPLSETPDLERFSVLYRVLDLVRYASGPEEKNVPLFTLVAATIERLCDTERDFQPILAGFLLRLVSVLGFTPALKRCVFSNYDLLGSIEEMQLDELLFVHDPGGFALPGSAVPMGATIQRVPVSHYLFIRALAATGSQAACPEASPEEVSAVTALLQEYCACHLGRMPHRKHLDIVSRLISA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS3_THEON
Sequence: MAIERYFIKEGVREMLIDEYLEKELRRAGYGGIDIKKTPLGTKVIIFAANPGYVIGRGGRRIRELTRILERQFGLENPQIEVEEIKNPYLNAKVQAVRLAQALERGVHFRRAAYAAIRAIMRNGARGVEIRISGKLTGERAKSVRFYQGYLAKVGNPAETLVSKGYAQALLKLGVIGVKVSIMPPDAKLPDEIEVIEKPIQEEEVSEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EFTS_ERYLH
Sequence: MAGFTAADVKKLREMSGAGMMDAKKALEETGGDLEAAVDALRAKGLAAVQKKSSRTAAEGLVGVAVEGTKGVAVEVNSETDFVAKNDQFQDFVRKTTAVALTIDGDDVEALKAADYPDGGTVTDKLTNNVATIGENQQVRRMKTVTVSQGVVVPYVHNAVAPNLGKIGVLVALESDASADVLEPLGKQLAMHIAAAFPQALDADGLDADLIERERKIAAEKAAESGKPENVQEKMVEGAIKKFAKENALLSQVFVMDNKTAIADVVLAAGKDAGTTITLKDYVRFQLGEGIEKEESDFAAEVAAAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.