PharMolix/UniProtQA huggingface dataset:
Protein: MPP10_ARATH
Sequence: MATVKDSGFEALEKLKATEPPVFLAPSSISEDARSASQYLFMKLKPHNPKCPFDQLSSDGFDAEQIWQQIDMQSQPLLTSLRQEVKRFAKNPEEIRKLGKLALKVSHEDDIDEMDMDGFDSDDVDDEDKEIESNDSEGEDEEEEEEDEEEEEEEEEEEEEEKDGDNEGIEDKFFKIKELEEFLEEGEAEEYGIDHKNKKGVAQRKKQNLSDDEDEEDDDDEEEDVEFDAFAGGDDEETDKLGKARYDDFFGGKKETKMKLKDLSEDEEAEIENKGNEKLSTHERARLKLQSKIEQMEKANLDPKHWTMQGEITAAKRPMNSALEVDLDFEHNARPAPVITEEVTASLEDLIKSRIIEARFDDVQRAPRLPTKGKREAKELDESKSKKGLAEVYEAEYFQKANPAFAPTTHSDELKKEASMLFKKLCLKLDALSHFHFTPKPVIEEMSIPNVSAIAMEEVAPVAVSDAAMLAPEEIFSGKGDIKDESELTQEDRKRRRANKKRKFKAESANEPPKKALDTSTKNP
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
M phase phosphoprotein 10, AtMPP10, U3 small nucleolar ribonucleoprotein protein MPP10.
What is the protein family that this protein belongs to?
Belongs to the MPP10 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: DAPA_HAEIN
Sequence: MSAQNSLFSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENVKVIEKTVEFAKGRIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGMYQHFKAIAECTDLPQILYNVPSRTGSDMKPETVARLAEIENIVGIKEATRDVSRIVKIKQLAGKNFIVLSGDDATGLEAIKLGAEGVISVTNNIAAKDMADMCRYALAGDFDKAEEINARLMRLHHDLFIESNPIPVKWAAYRLGLIKSPHLRLPLTTLSEEIQPKVGDALKIAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_HERAR
Sequence: MDIKRTVLWVIFSFSLLMLWDNYNRYTGKPSIFFDSTTTQQAAAPAATGNNAAKTADAPTAATTAATSGANTPGVPDGAAAVKSEVITITTDLMKIGIDTAGGEVRHLELLKHHESGDESKNVVLFDENGQHTYLGQTGLIGGAYPNHKSMFAAVPGPRTLDSANQVQLVLQSEQQGVKLIKTFTFKRGEYKVDIKHDVVNNTSTAITPSLYLQLVHDGSALGGGSMFMASAFTGPAIYTEADKFQKVTFESIEKGKAEHAMKGESGWIALVQHYFVSAFVPPANTPREYFTKKLATNLYAVGTILPMGTVAPGATASMDTTMYSGPQESKRLEAVAPGFELVKDYGWLTIIAKPIFWLMMQIHQILGNWGWTIIVLTIVIKLAFFPLSAAGYRSMAKMKLVTPKMTDIRTRYKGEPQKMNAAMMELYKKEKINPIGGCFPMLVQIPVFISLYWVLLASVEIRNASWLWIHDLAAPDILFGSYHIGTFHLTIGILPILMAISMFIQTKLNPTPPDPIQAKVMMFMPIAFSVMFFFFPAGLVLYWVVNNILSIAQQWFINEKLLGGKAKA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CGL_PIG
Sequence: MQEKDVSSHGFLPRFQHFATQAIHAGQEPEQWASKAVVPPISLSTTFKQEAPGQHSGFEYSRSGNPTXNCLEKAVAVLDGAKYSLAFASGLAATVTITHLLKAGXQIISMDDVYGGTNRYFRQVAAEFGLKISFVDCSKSKLLEAAITPETKLVWIETPTNPILKMIDIEACAQIVHKHGDIILVVDNTFMSAYFQRPLALGADICMYSATKYMNGHSDVVMGLVSLNSETLHSRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESHPLVEKVIYPGLPSHPQHELAKRQCTGCPGMISFYIKGSLHHAETFLKSLKLFTLAESLGGYESLAELPAIMTHSSVPKSDREVLGIRDTLIRLSVGLEDKQDLMDDLDQALKAAHPTNASHN
What is the function of this protein?
Catalyzes the last step in the trans-sulfuration pathway from L-methionine to L-cysteine in a pyridoxal-5'-phosphate (PLP)-dependent manner, which consists on cleaving the L,L-cystathionine molecule into L-cysteine, ammonia and 2-oxobutanoate.  Part of the L-cysteine derived from the trans-sulfuration pathway is utilized for biosynthesis of the ubiquitous antioxidant glutathione.  Besides its role in the conversion of L-cystathionine into L-cysteine, it utilizes L-cysteine and L-homocysteine as substrates (at much lower rates than L,L-cystathionine) to produce hydrogen sulfide (H2S).  In vitro, it converts two L-cysteine molecules into lanthionine and H2S, and two L-homocysteine molecules to homolanthionine and H2S, which can be particularly relevant under conditions of severe hyperhomocysteinemia.  Lanthionine and homolanthionine are structural homologs of L,L-cystathionine that differ by the absence or presence of an extra methylene group, respectively.  Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.  By generating the gasotransmitter H2S, it participates in a number of physiological processes such as vasodilation, bone protection, and inflammation (By similarity).  Plays an essential role in myogenesis by contributing to the biogenesis of H2S in skeletal muscle tissue (By similarity).  Can also accept homoserine as substrate (By similarity).  Catalyzes the elimination of selenocystathionine (which can be derived from the diet) to yield selenocysteine, ammonia and 2-oxobutanoate (By similarity).
What are the official names of this protein?
Cystathionine gamma-lyase, CGL, CSE, Cysteine desulfhydrase, Cysteine-protein sulfhydrase, Gamma-cystathionase, Homocysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT_ECO7I
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWSFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_RHIWR
Sequence: MDIRAAEISKVIRDQIASFGSEAQISEVGQVLSVGDGIARIHGLDNVQAGEMIEFSNGIKGMALNLEADNVGAVIFGSDSQIKEGDVVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGPIVAEQRSRVEVKAPGIIPRKSVHEPVQTGLKALDALVPVGRGQRELIIGDRQTGKSAVAIDTFINQKTANAGTDESKKLYCVYVAIGQKRSTVAQLVKTLEENGAMEYSIVVAATASDPAPLQYLAPYTGVAMGEYFRDNGMHGLIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDANGNGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQGVRPAINVGLSVSRVGSAAQTKAMKKVAGSIKLELAQYREMAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFQPLPFEEQVASIFAGVNGYLDSIPTNAVTRFEAGFLAEMRSKHADVLAAIRDSKDLSADSTAALKSALEAFVKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NB5R3_RAT
Sequence: MGAQLSTLSRVVLSPVWFVYSLFMKLFQRSSPAITLENPDIKYPLRLIDKEIISHDTRRFRFALPSPQHILGLPIGQHIYLSTRIDGNLVIRPYTPVSSDDDKGFVDLVVKVYFKDTHPKFPAGGKMSQYLENMNIGDTIEFRGPNGLLVYQGKGKFAIRADKKSNPVVRTVKSVGMIAGGTGITPMLQVIRAVLKDPNDHTVCYLLFANQSEKDILLRPELEELRNEHSSRFKLWYTVDKAPDAWDYSQGFVNEEMIRDHLPPPGEETLILMCGPPPMIQFACLPNLERVGHPKERCFTF
What is the function of this protein?
Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor.
What are the official names of this protein?
NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid- anchor; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Note=Produces the soluble form found in erythrocytes.
Protein: PYRG_MYCCC
Sequence: TMVTKLEKDSLVSKLYNSDVALERHRHRYEFNNKYKKDLESVGLRFSGIYEEKNLVEVIEIPSLKFFVASQFHPEFTSRPNKPTPLFKGFIKAIIENNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DC1L2_HUMAN
Sequence: MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKDFQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in binding dynein to membranous organelles or chromosomes.
What are the official names of this protein?
Cytoplasmic dynein 1 light intermediate chain 2, Dynein light intermediate chain 2, cytosolic, LIC-2, LIC53/55.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RUVB_STAAB
Sequence: MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIKAAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDDESAIELAKRSRGTPRVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNGGPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYGHFAKSNEERE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MOC2B_ASPFU
Sequence: MATQPPQDQTSTTPSLPPHLDPTTYPRILTSATHNIHLELTYSTLNPTVALEHTSSPAAGANVLFLGTTRDTFEGRAVSQLSYTSYPPLALKSLMSIATRAVEKFDLKGVYIAHRLGVVPISEASIVVAVSAGHRGMAWKAAEEVLEEVKEKVEIWKREEFVDGGMEWRENRERDAEGRILSSTEGGK
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Common component for nitrate reductase and xanthine dehydrogenase protein H, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPPA_LACLS
Sequence: MNKLKVTLLASSVVLAATLLSACGSNQSSSTSTKKLKAGNFDVAYQNPDKAIKGGNLKVAYQSDSPMKAQWLSGLSNDATFATMSGPGGGQDGLFFTDSGFKFIKGGAADVALDKESKTATITLRKDLKWSDGSEVTAKDYEFTYETIANPAYGSDRWTDSLANIVGLSDYHAGKAKTISGITFPDGENGKVIKVQFKEMKPGMTQSGNGYFLETVAPYQYLKDVAPKDLASSPKTTTKPLVTGPFKPENVVAGESIKYVPNPYYWGKKPKLNSITYEVVSTAKSVAALSSSKYDFINGMVSSQYKQVKNLKGYKVLGQQAMAISLMYYNLGHYDAKNSINVQDRKTPLQDQNVRQAIGYARNVAEVANKFSNGLSTPANSLIPPIFKQFTSSSVKGYEKQDLDKANKLLDEDGWKLNKSTGYREKDGKELSLVYAAHVGDANAETIAQNYIQQWKKIGVKVSLYNGKLMEFNSWVDHMTTPPGANDWDITDGSWSLASEPSQQDLFSASAPYNFGHFNDSEITKDLNDIDSAKSENPTYRKAAFVKYQEDMNKKAYVVPTNFSLSYTPVNKRVVGMTLDYGAMDTWSEIGVSSAKLATK
What is the function of this protein?
This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
What are the official names of this protein?
Oligopeptide-binding protein OppA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS17_ROSDO
Sequence: MPKRILSGVVTSDANDQTVSVSVERRFTHPVLKKTIRKSKKYRAHDENNTFKKGDAVRIVECAPKSKTKRWEVLQAAEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: END4_HALH5
Sequence: MTLHLGSHVSMNGKKMLLGSSEEAISYGANTFMVYTGAPQNTRRKPIEELNIEAGRAHMKENGIDHIIVHAPYIINIGNSEKPATFKLGVDFLQSEIERTQALGADQIVLHPGAHVGAGVDKGIEKIIEGLNEVLTENDGVQIALETMAGKGSECGRTFEEIARIINGVTHNDRLSVCFDTCHTHDAGYNIVEDFDGVLNEFDKIIGVERIKVLHINDSKNPRGAAKDRHENIGFGHIGFKALHYIVHHPQLQDIPKILETPYVGEDKKNKKPPYKFEIDMIRNGTFHEGLLEKIVAQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: HFLD_YERPY
Sequence: MAKNYYDITLALAGICQSARLVQQLAHEGQCDNDALNTVLRGLLQTNPSSTLAVYGDTEQVLKMGLETLQSVLNANRQGEAAELTRYTLSLMVLERKLSASKSAMNTLGERISQLDRQLAHFDLESETMMSSLASIYVDVVSPLGPRIQVTGSPAILQSPLVQAKVRATLLAGIRSAVLWQQVGGSRLQLMFSRNRLFKQAQSILAHT
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y4345_ARATH
Sequence: MSDSGGGSHKSSTTKPSVFGLNLYLVIAICSVFILLISLLIFLFVCLNRVSRARRMRVKHSSGSIPLVSKEISEIKTVGKFINSDDSKGKIGNEVVVVVSATSKEATSGFDTLSVASSGDVGTSEAMGWGKWYSLKDLEIATRGFSDDNMIGEGGYGVVYRADFSDGSVAAVKNLLNNKGQAEKEFKVEVEAIGKVRHKNLVGLMGYCADSAQSQRMLVYEYIDNGNLEQWLHGDVGPVSPLTWDIRMKIAIGTAKGLAYLHEGLEPKVVHRDVKSSNILLDKKWNAKVSDFGLAKLLGSETSYVTTRVMGTFGYVSPEYASTGMLNECSDVYSFGVLLMEIITGRSPVDYSRPPGEMNLVDWFKGMVASRRGEEVIDPKIKTSPPPRALKRALLVCLRCIDLDSSKRPKMGQIIHMLEAEDFPFRPEHRSNQERSK
What are the official names of this protein?
Probable receptor-like serine/threonine-protein kinase At4g34500.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TESB_ECOLI
Sequence: MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQALYAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIFYMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEVRPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIGFLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVASTVQEGVMRNHN
What is the function of this protein?
Thioesterase that has relatively broad substrate specificity, hydrolyzing primarily medium- and long-chain acyl-CoA substrates to free fatty acids and CoA (PubMed:1645722, PubMed:24271180, PubMed:20547355).  Functions in the thioesterase-dependent pathway of beta-oxidation of oleate and conjugated linoleate ((9Z,11E)-octadecadienoate or CLA), which provides all energy and carbon precursors required for the growth of E. coli.  Thus, supports growth on oleate or conjugated linoleate as the sole source of carbon by hydrolyzing 3,5-tetradecadienoyl-CoA, the terminal metabolite of oleate beta-oxidation via the alternative thioesterase-dependent pathway, and 3,5-dodecadienoyl-CoA, the end product of CLA beta-oxidation, respectively (PubMed:18702504, PubMed:14707139).  Seems to be involved in 3-hydroxyalkanoate production in E. coli (PubMed:20547355).
What are the official names of this protein?
Acyl-CoA thioesterase 2, Thioesterase II, TEII.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
Protein: SYP_STAA8
Sequence: MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLPLATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGRQFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGEDTIVYSKESDYAANIEKAEVVYEPNHKHTTVQPLEKIETPNVKTAQELADFLGRPVDEIVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLGPVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDEYGDFRFILEGEKLSDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQSLIMGCYGIGISRTLSAIVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQERAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLMTVITNKYDNLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_NEIG1
Sequence: MALLQISEPGMSAAPHRHRLAAGIDLGTTNSLVATVRSGSAACLPDADGRVTLPSVVRYLENGGIEVGKTALSAQKTDPLNTVSSAKRLIGRTLADLHQNTHYLPYRFGDNQRFIELHTRQGVKTPVEVSAEILKTLKLRAEETLGGDLVGVVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNASEGTFVVYDLGGGTFDVSVLQLTKGLFEVKATGGNSALGGDDFDHRLFCYLLEQNRLSQLNEQDSQLLLSLVRAAKEQLTTQTEARIQATLSDGMAIDTSISRAEFHNLTQHLVMKTLEPVKQALKDAGVGKNEVKGVVMVGGSTRMPHVQQAVATFFGQTPLNNLNPDEVVALGAAIQANVLAGNKADGEWLLLDVTPLSLGLETYGGLAEKIIPRNSTIPTARAQDFTTFKDGQTAMTIHVVQGERELVSDCRSLAKFTLRGIPPMAAGAARIRVTFQIDADGLLSVSAQEQSTGVQAQIEVKPSYGLDDDTITQMLKDSMGNAAEDMAARARAEAVVEAESLTDAVNAALELDSDLLDAEEFAQIQRDIADLQGRLKDGKAEDIRAAVAKLSRSTDNFAAKRMNRNIQRALTGQSVDNI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FMT_ACICJ
Sequence: MRLAFMGSPGFAVPALRALHAAGHDIVAVYCQPPRPVGRGHRIHKCPVHEAAEALGLTVRTPERLRRDDAERAYFRALDLDAAVVAAYGQILPADMLVAPRRGCINIHASLLPRWRGAAPIHAAILAGDAQTGVTIMQMDEGLDTGATLLAEAVPIGPEDTMVDLLDRLADLGAALVIKVLDGNFPPVPQPEGGVTYAPKLSKADAEIDWSASAAVILRRIRAFRPWPGTETRLDGEALKIIRAEPAAGQGEPGTVLDDRLAIACGDAAIRPTLVQRAGRAAMQAEAFLRGHPVAIGTRLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RIMO_LEGPA
Sequence: MNHKVGFVSLGCPKALVDSERIITQLKAQGYELVPTYEDAGVVVINTCGFIDSAVQESLDTIKEAMAENGRVIVTGCLGAKADVIKNACPDVLHISGAHAYEEVVNAVHQHLPPPADPFTQLIPPQGIKLTPRHYAYLKISEGCNQKCTFCIIPTMRGKLQSYPMAQILTEAKKLKQAGVKELLVISQDTSAYGVDTRYQQIEWQGKTVNTRFYDLCEQLGELGIWVRLHYVYPYPHVDDIVPLMRDGLILPYLDIPLQHANSRILKAMKRPASSENTLLRIASWREICPDITLRSTFIVGFPGETEEEFSELLAFLKEAQLDRVGCFKYSPVEGAKANDLDNPVSEDIKEERYHRFMQVQAEISRNKLKNKIGSTQTVLIDEITEDQIIARSKSDAPEIDGLVYLPKISGITVGSFAEAMITDSDDYDLYGDLEYSLA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPNE7_RAT
Sequence: MSGDSERTVAPGVVPAPCASKVELRLSCRHLLDRDPLTKSDPSVVLLQQAQGQWLQVDRTEVVKSSLHPVFSKVFTMDYYFEEVQKLRFEVYDTHGPSGLSCQDDDFLGGMECTLGQIVAQKKMTRPLLLRFGRNAGKSTITVIAEDISGNNGYVELSFQARKLDDKDLFSKSDPFLELYRVNDDGSEQLVYRTEVVKNNLNPVWEPFKVSLNSLCSCEETRPLKCLVWDYDSRGKHDFIGDFTTTFAEMQKAFEEEQAQWDCVNAKYKQKKRNYKNSGVVILADLKLHRVHSFLDYIMGGCQIHCTVAIDFTASNGDPRNSCSLHHINPYQPNEYLRALVAVGEVCQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARMAAAEERTGEASQYYILLILTDGVVTDMSDTREAIVRASHLPMSVIIVGVGNADFTDMQILDGDDGILRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHKDLPPRSLGGQTGEAGPSSAP
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
What are the official names of this protein?
Copine-7, Copine VII.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Translocates to the cell membrane in a calcium-dependent manner.