PharMolix/UniProtQA huggingface dataset:
Protein: MDH_METNO
Sequence: MARKKIALIGAGQIGGTLAHLAGLKELGDVVLFDIADGVPQGKGLDIAESAPVDGFDAKYSGASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGTGIKTHAPNAFVICITNPLDAMVWALQKFSGLDPKKIVGMAGVLDSARFRHFLAEEFSVSVEDVTAFVLGGHGDDMVPLVRYSTVAGIPLPDLVKMGWTTQEKLDAMVERTRKGGGEIVNLLKTGSAFYAPAASAIAMAESYLKDKKRVLPCAAYLTGQYGVDGLFIGVPIVIGENGVERIVEVAFSAEEKAMFDKSVNSVKGLVEACKGINAALA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: CYB_CAPHE
Sequence: MTNIRKTHPLMKIVNNTFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHIGRGLYYGSYTFLETWNIGVILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPTGIPSDTDKIPFHPYYTIKDILGAMLLILVLMLLVLFTPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLVPFLHTSKQRSMMFRPISQCMFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLIILVMMPAASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CSKP_RAT
Sequence: MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHHVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPERFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPTITPGLNEDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY
What is the function of this protein?
Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking (By similarity).  Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. ontributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1.  Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans.  May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4. 1.  Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).
What are the official names of this protein?
Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: PLSX_ECOLU
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDAITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFELLDGGKSGTLR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CAD8A_ORYSJ
Sequence: MEHDGTAALGWAARDASGHLSPFSFTRRVQEEDDVTIKVLYCGICHTDLHTIKNEWGNAMYPVVPGHEIVGVVAGVGAGVTRFKAGDTVGVGYFVDSCRACDSCGKGDENYCPTMVITSNGTDYGGATTQGGFSDVMVVRQDYVLRVPASLPPDGAAPLLCAGVTVYSPMVEYGLNAPGKHLGVVGLGGLGHLGVKFGKAFGMKVTVISSSPAKREEALERLGADAFLSSRDGEGMAAAAATMDGIIDTVSAGHPLVPLLSLLKPKGQMVVVGAPAAPLQLPAIAIIDGGKRVAGSGGGSVAECQAMLDFAGEHGIAADVEVVAMGDVNAALGRLERNDVRYRFVIDVAGTLHAAAAPS
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 8A, OsCAD8A.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: MNMG_RICRS
Sequence: MLKYDVIVIGGGHAGVEAAAASARLGVPTLLITLKPENLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKMLNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKIEAVILNNGSKILCQKIILTTGTFLSGLIHIGQKKIPAGRVDEEPSYGLSNTLKQIGFKLARLKTGTPPRIDGRTIDYSKTILQPGDKIPRPFSELTNIVNVSQINCFITKTTSETHDIIRENLDKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKLIKTIPGLENVKVLRPGYAIEYDYVDPREISVTLETKKIAGLYLAGQINGTTGYEEAAGQGIIAGINAALAVKDQAPFMLTRANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNSDLRLTELGMNIGVVSEKRKKIFTKKCEDIEKIKSLLNTLSLTTSKLAKMGIQVAQDGTYKTVLDLFKIPNFNVEQAIKIFPMLKETQNNNILQLLYIEAKYASYLTRQQADINLFQSEEAQFIPKNIDYFKIPSISLEIQEKLSAHKPTTIGVARRIPGITPAAITAIIIYLKTKYSDGSST
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_NITSB
Sequence: MLIDGHGRKVDYLRISLTERCNFRCQYCMPEKPFSWVPKENLLNFEDLFKFVKAAIDEGITKIRLTGGEPTLRADLDKFIKMIYDYKPDIDLAMTTNGYLLKDIAQDLKKAGLKRLNISLDSLKPEVAAKIASKDVLKNVLEGIDAALEAGLKVKINMVPLKGVNEDEIVDVMEYCKDRGMQIRFIEYMENVHAHSDLVGMHGKEILDKIKQKYEIEKIGRQGSSPAFLYKLKEDGYIFGLIDPHKHDFCETCNRIRLTAEGYLIPCLYFDEAMSIKEAVQAGDIDRAVEILKTVLANKPKENRWSEDANEASNRAFYETGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: KMT5C_RAT
Sequence: MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMNVSPVPTLRRQHHLRSALEAFLRQRDLEAAFRALTLGGWMAHYFQNRAPRQEAALKNHIFCYLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVGCIAELREEDEYLLRAGENDFSVMYSTRKRSAQLWLGPAAFINHDCKPNCKFVPSDGNTACVKVLRDIEPGDEVTCFYGEGFFGEKNEHCECYTCERKGEGAFRLQPREPELRPRPLDKYELRETKRRLQQCLDSSQQNLLSLRACSHLSPLRPDPFCAACQPSCLLPVSPHMDYLPLWLQWVPQPQPRVRPRKRRRRRRRRPRIPQASLSPDLHTACVSLHRWGGCGPHCQLRAEAMVTLHLLPQTRWTPKQDWYWARRYGLPSVVRVELSPLAPALPAAPAPAGNLGPTPTPDLIPKQALAFAPFCPPKRLRLVVSHGSIDLDINSGEP
What is the function of this protein?
Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity.  In vitro also methylates unmodified 'Lys-20' (H4K20me0) of histone H4 and nucleosomes (By similarity).  H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression.  Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions.  KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).  Facilitates TP53BP1 foci formation upon DNA damage and proficient non-homologous end-joining (NHEJ)-directed DNA repair by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity).  May play a role in class switch reconbination by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase KMT5C, Lysine-specific methyltransferase 5C, Suppressor of variegation 4-20 homolog 2, Su(var)4-20 homolog 2, Suv4-20h2, [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B, [histone H4]-lysine20 N-methyltransferase KMT5B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin.
Protein: MFGM_MOUSE
Sequence: MQVSRVLAALCGMLLCASGLFAASGDFCDSSLCLNGGTCLTGQDNDIYCLCPEGFTGLVCNETERGPCSPNPCYNDAKCLVTLDTQRGDIFTEYICQCPVGYSGIHCETETNYYNLDGEYMFTTAVPNTAVPTPAPTPDLSNNLASRCSTQLGMEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASNYDSKPWIQVNLLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRKFEFIQDESGGDKEFLGNLDNNSLKVNMFNPTLEAQYIKLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQMSASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGSSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRLELLGC
What is the function of this protein?
Contributes to phagocytic removal of apoptotic cells in many tissues.  Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors.  Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner.  Zona pellucida-binding protein which may play a role in gamete interaction (By similarity).  Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing.  Promotes VEGF-dependent neovascularization.
What are the official names of this protein?
Lactadherin, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1, Sperm surface protein SP47, MP47.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein. Note=Located in the acrosomal region of zona-pellucida bound sperm.
Protein: EFTS_FRATT
Sequence: MSNISAKLVKELRERTGAGMMECKKALVAAAGDIEKAAEEMRISGQAKADKKASRVAAEGVIEVYAADGRAILLEINSETDFVARDETFKKFAQEAVKAAHAANAKTIEEVLAAKTSNGETVEEVRKSLIAKIGENIQVRRVKTVEAETLGAYIHGSKIGVVAALEGGDEDLAKDVAMHVAAANPMVVSGDQVPADVVAKEKEIFTAQAKESGKPAEIIEKMIVGRIRKFLDEVALLGQDFVKDPAIKVEKLVKDKGAKVVNFIRLDVGEGIEKKEEDFAAEVMSQIKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTBP3_ARATH
Sequence: MAESSKVVHVRNVGHEISENDLLQLFQPFGVITKLVMLRAKNQALLQMQDVSSAVSALQFFTNVQPTIRGRNVYVQFSSHQELTTIEQNIHGREDEPNRILLVTIHHMLYPITVDVLHQVFSPYGFVEKLVTFQKSAGFQALIQYQVQQCAASARTALQGRNIYDGCCQLDIQFSNLEELQVNYNNDRSRDYTNPNLPAEQKGRSSHPCYGDTGVAYPQMANTSAIAAAFGGGLPPGITGTNDRCTVLVSNLNADSIDEDKLFNLFSLYGNIVRIKLLRNKPDHALVQMGDGFQAELAVHFLKGAMLFGKRLEVNFSKHPNITPGTDSHDYVNSNLNRFNRNAAKNYRYCCSPTKMIHLSTLPQDVTEEEVMNHVQEHGAVVNTKVFEMNGKKQALVQFENEEEAAEALVCKHATSLGGSIIRISFSQLQTI
What is the function of this protein?
Plays a role in pre-mRNA splicing.  Binds to the polypyrimidine tract of introns.  May promote the binding of U2 snRNP to pre-mRNA (By similarity).
What are the official names of this protein?
Polypyrimidine tract-binding protein homolog 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAPSD_MSVTA
Sequence: MSTSKRKRGDDANWNKRTTKKKPSSAGLKKAGSKAERPSLQIQTLQHAGSTMITVPSGGVCDLINTYARGSDEGNRHTSETLTYKIAVDYHFVADSQACKYSNTGTGVMWLVYDTTPGGQAPTPQTIFAYPDTLKAWPATWKVSRELCHRFVVKRRWLFNMETDGRIGSDIPPSNASWKPCKRNIYFHKFTSGLGVRTQWKNVTDGGVGAIQRGALYMVIAPGNGLTFTAHGQTRLYFKSVGNQ
What is the function of this protein?
Encapsidates the viral genome into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement.  The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell-to-cell movement and spread (By similarity).
Protein: QADG_PSEPU
Sequence: MSAVAGCTATTDPGWEVDAFGGVSSLCQPMEADLYGCSDPCWWPAQVPDMMSTYQDWNAQASNSAEDWRNLGTVFPKDK
What is the function of this protein?
Catalyzes the oxidative deamination of a wide range of aliphatic monoamines and diamines (PubMed:27315927).  The physiological electron acceptor is an azurin-like blue protein (PubMed:27315927).
What are the official names of this protein?
Quinohemoprotein amine dehydrogenase subunit gamma, QH-AmDH, Quinohemoprotein amine dehydrogenase 9 kDa subunit, Quinohemoprotein amine dehydrogenase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the quinohemoprotein amine dehydrogenase subunit gamma family.
What are the subcellular locations of this protein?
Periplasm. Note=Is probably co-translocated into the periplasm when associated with the alpha and/or beta subunit, which contain both a signal peptide.
Protein: ENO_ALKMQ
Sequence: MTIISDVYAREVLDSRGNPTIEVEVYLESGVLGRAIVPSGASTGAFEAVELRDGDKGRYLGKGVLKAVENVNDIIAPEITGLDALDQVAIDKIMLDLDGTPNKAKLGANAILGVSMAVAKAAAEALDIPLFQYLGGVNAKQLPVPMMNILNGGSHADNNVDIQEFMVMPVGAKTFKEALRMGTEIYHNLKDVLKSKGLATGVGDEGGFAPNLSSNEEALQIIMEAIEAAGYKPGVDIKLALDVAATEFYDEDEKLYKLTGEGVTKTAEEMVDFYEALVKKYPIVSIEDGLSEDDWEGWRVMTERLGDNIQIVGDDLFVTNTERLKKGIQTKTANSILVKLNQIGTITETLDAIEMAKRAGYTTVISHRSGETEDATIADIAVAVNAGQIKTGAPARTDRVAKYNQLLRIEDMLGFTGQYIGNEVFYNIKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KTHY_MYCPU
Sequence: MKIENKSDKEEDQMFITFEGIDASGKTSLLAKLKAHVVQKNLQGKCTFTWEPGGRKSPEIQTIRHLILNKESNLSPIAEAFLYSSARRIHLDKVILPNLAKNKVVFCDRFVDSSFAYQAFGRDLGFEKIKLLNELATDKKYPDITFILKISYEESMERRKARQEDEDRLEKEENSFYQKVIKGYDFLASYPEFQKRIFVIDASKNQEEIFESVLKILKDHKTFQTHPIYKDFFS
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DEC1_COCH4
Sequence: MTITGQINSETLNNGVPIFAPPYRWSKHWPRFTDVNCITIRYRTDGSSIRQYIPDNLQIEETPIVTIMLLDFGFSVIGPYHELIHCVEVTYEGKKYNYSFLLILDNEEACIGGRELLGNPKVLGTIEFDRQNRPPTAFIHGRVLRPSNTVIADIHFKPLCLVLDAGESKTPITGLNLRLIPSLIPGAPPSVREYTNVDFTLQGGEVWEGVGSLNFPSNSEFEPLHKFPVLEYLSATYHRGAWVEQRLLNVYSF
What is the function of this protein?
Decarboxylase; part of the Tox1B locus, one of the 2 loci that mediate the biosynthesis of T-toxin, a family of linear polyketides 37 to 45 carbons in length, of which the major component is 41 carbons, and which leads to high virulence to maize (PubMed:8953776, PubMed:20192833).  One of the PKSs (PKS1 or PKS2) could synthesize a precursor, used subsequently by the other PKS as starter unit, to add additional carbons (PubMed:16529376).  Variability in the length of the final carbon backbone C35-47 could be achieved by varying the number of condensation cycles, or use of different starter or extender units or might be due to decarboxylation of the penultimate product, catalyzed by DEC1 (PubMed:12236595).  Additional proteins are required for the biosynthesis of T-toxin, including oxidoreductases RED1, RED2, RED3, LAM1 and OXI1, as well as esterase TOX9 (PubMed:20192833).
What are the official names of this protein?
Decarboxylase DEC1, T-toxin biosynthesis protein DEC1.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: CS111_YEAST
Sequence: MSSASRLQNVNIVSNNYSRYGTSVYDKLYHSNGSGSNNAGKNSTTVGKLSSISQKSRSKQRHGSNCSRSMSQSPLSTFKSPLSNQNQSSAPDDLASIGQRRSDDVTSLDNETIITMNSRKSRIKKKYKSLISTSSKKFMNKLYDHGASSDSFSIFSLKTSHSGKHENSRFEKLRKRKYHAWGKFADINDLPVEIIAKILSEFELGRDQKTLVRCLYVSKKFYKATKIVLYRLPYFTSTYRVAQFVTSLRLHPDNGAYVKVLDLSHLKPGIIGQDSKDSQGLDDDGHSRRHRRRRRRSTNTSLNLPPATPTSTISNEDDANSGLIKDDASNGSEVEDLALAGWRDWRYRNEPLYSSPLLNSFKLKKVVSRSSSITSTSSGNSTGVHSTRRQRSNSSVASITTSIMSSIYNTSHVSLSSTTSNTSNGNISSGSNLSRVSTAGSLKKASAKSTRSSPQKAKPISDITSSSWFRMRLSSRNRKARTANTINLKNSKDKSDDDFKVLKHDSGHPSNYRSSTLKFSIEQPFSTHHPYANKFLLKYAPYKDLPLGYILHMLNLCPNLVELNLSNLVICTDFKLINQRSERRRMTSSLLPAVQESSVSAGPEKDLEIVYMTDSGKGYEYYEGLSKKHSRSSSLGTNPSSWIGGQANWTDYPPPIDAQTKTREEHRRNNTLNNKNVVLKKLNPFEIFEMICNRNEEKGGYCSLTKVKMNDIVWCRQYMVKYFVMRTFRQHLDYKSMENNSYERHLFSFRDSGLDRNFSWACNAKLHEFVALMVMDHLSNLDDLGLEELFNIKSEKLYIKNYCCRDPDILEISNLFDIRYGAGSEADATSDSNLEAESLQFRLTILKTEKPTSFWLTKVSKDYVSLVVKLCVDDDIDMDKMKVGKPTLRIDSITHNLISRLKELRRVDLRRNVGENNYYAESII
What is the function of this protein?
F-box protein probably involved in ubiquitin conjugation pathway.  Involved in the resistance to ciclopirox olamine (CPO), a synthetic antifungal agent.
What are the official names of this protein?
F-box protein COS111, Ciclopirox olamine sensitivity protein 111.
Protein: RIMM_PHOV8
Sequence: MIKKDEVFKIGIFNKPHGVKGEISFTFTDDIFDRVECEYLVCLLDGIFVPFFIEEYRFRSDTTALVKLEGVDTSEKARMFTNVEVYFPKKYVGEEEDSDDIPTWNYFIGFKVEDVNHGELGEIVAVDDSTMNVLFAIEKGGEELLLPAHEEFITKLDKKKRLLTVEVPDGLI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO186_YEAST
Sequence: MTLAFTTFAISKINNSSTNEDSKVMILCDEHHPFEKGYFKSAIRAFGNSIKLGLMGNSRPEDAASIFQDKNIPHDLTTEEFRLQLVCMAFSWFIFGLFIACLLLCITLVLTSRYPGENENKATEVVPSSNIDDEEKQLSLSDMI
What are the official names of this protein?
Putative uncharacterized protein YOR186W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RLMH_FLAJ1
Sequence: MNIKLIAIGKTDNKSLQTLIDDYTKRLSFYIKFDLEIIPDIKNVKNLSESQQKEKEGELILSKLSATDQLILLDENGKTFSSVGFSEELQKKMNSGVKTLVFVIGGPYGFSETIYKKAQGKVSLSLMTFSHQMVRLFFIEQLYRGFTILRNEPYHHQ
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_AZOVD
Sequence: MSRIGTPLSPGATRVLLCGSGELGKEVVIELQRFGVEVIAVDRYADAPAMQVAHRSHVINMLDGAALRALIEQERPHYIVPEIEAIATATLVELESEGFTVIPSARAANLTMNREGIRRLAAEELGLPTSPYRFADSFEEYRAAAEALGFPCVVKPIMSSSGKGQSLLKGPEQLQAAWDYAQEGGRAGKGRVIVEGFIDFDYEITLLTVRHAGETTFCAPIGHRQEKGDYQESWQPQAMSTTAQAESERIARTVTEALGGRGLFGVELFVKGDQVWFSEVSPRPHDTGLVTLISQDLSEFALHARAILGLPIPAIRQFGPAASAVILVEGQSREVGFANLGQALAEPDTALRLFGKPEVAGQRRMGVALARDVSVETARQKATRAAQAVEVQL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: YAAA_ECOL6
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPPQISSLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: QTC_DROME
Sequence: MMTSLQLETSLPAVEEQVQREKDNDSAEDSHTASTTPTRIPHPAVARFRRSASLRLRGNPAELGLRAEHCPAGGGGFSSRAKLTAIPSSLETRSHPVHLRRNRSWCNLGHKTEQEPEVEASTEALCNAAQCLSLDKEALAPKVGNSSMANGKPRNLSLQLNGGSDISSSGTSSSSSNNKESSPRTTRTPRTPQTPQTPQTPASGVAASVAETPHSCIRQGNCVKANQVKLSTLHESKISPRTPPVTPDSPSTYLDDDIDSMYSFATTTSGRSTMSCEHPYVARNGTTFSGRKMKYVVHCSNYAGQVGPDYLTPTQRAQRQIRRLKELLCIARQDLEQKDTELLRLTREVVELRLFKASLSSPEERSASSDAVTVREAELKTSQDVSPIVDMVDEGNAKGSPRHLSRQQQQQANHSLQAMQMSAEMQSSYADSGHFEDLTMSSVHSKDSQTQSEACGTATPDGEADVGCGAGGDSASNLENYELQRQELISMYEHRIEELIRSQDSATSDLKRSHNDKVEALLQKLAECNTRYSDMVPDYEQAKQRIRELEKQLEDLQRKLIEHEEKQNKMYLHMYQQGQEAERISRADQALDLAQRQPESKVSINELLHQLQSTQDELENIRASECRMRECGSNHALLTAKEAISLWVLGARKTIYRRLLEAQKNRTHVDPEVTLQFLKSAIFYFLTDKENSQGHLQAIESILEFTDAEKQKISAANRTPK
What is the function of this protein?
In adult males, modulates sexual behavior by playing a role in sex discrimination and maintaining normal levels of sexual activity towards both males and females.
What are the official names of this protein?
Protein quick-to-court.