PharMolix/UniProtQA huggingface dataset:
Protein: EFTS_RHILO
Sequence: MSISAAQVKELRDLTGAGMMDCKAALNETNGNMEEAVDWLRKKGISKADKKAGRTAAEGLIGVDAGVREAAVVEVNSETDFVARNAAFQEIVANVAKVALAYGTTEAVAAAKYPGSDKSVTDTIKDAVGTIGENLGFRRSAKLTVPHGAVATYVHNAVADGLGKLGVLVAIETTGNEHAANAFGRQVAMHVAATNPMALTAEQIDPAAVEREKAIFSDQARQSGKPEAIIEKMVEGRMRKFYEEVVLLKQAFVLNPDITVEKALKDAEKEIGAPAKITAYLRFALGEGIEKEETDFAAEVAAAVKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGCA_STAA3
Sequence: MKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLQSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGFEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
What is the function of this protein?
Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate.  This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i. e.  the predominant glycolipid found in the S. aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity).
What are the official names of this protein?
Phosphoglucomutase, PGM, Alpha-phosphoglucomutase, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TYRR_ENTAG
Sequence: MRLEVFCQDRIGLARELLDLLVARSIDLRGIEVAASGRIYLNFSTLEFEQFSNLMAEIRRTPGVTDVRTVPYMPSEREHRVLSALLVAMPEPVFSVDLRTKVELANPAAQNLFNLDENKIRNFTADHLINGFNFARWLESERVQAQAQHVVIEGRDFLMEAHPIYLSEDNDQADQLVGAMVMLKSTARMGRQLQNLVVTDETEFDHIVAVTPRMRQVVEQARKLAMHDAPLLIIGDTGTGKDMLARACHLRSARGKMPFLALNCASLPDDVAESELFGHAAGAYPNALEGKKGFFEQANGGSVLLDEIGEMSPTMQTKLLRFLNDGTFRRVGEEHEVHVNVRVICATQKNLFELVQRGEFREDLFYRLNVLTLNLPPLRERVQDIMPLTEIFVARFADEQGIPRPRLSSQLNAFLMRYNWPGNVRQLKNALYRALTQLEGHELRPQDIVLPEQALDVSLGEEAMEGTLDQITSRFERSILTRLYLSYPSTRKLAKRLGVSHTAIANKLREYGLGQKRGDNE
What is the function of this protein?
Dual transcriptional regulator of the TyrR regulon, which includes a number of genes coding for proteins involved in the biosynthesis or transport of the three aromatic amino acids, phenylalanine, tyrosine and tryptophan.  These three aromatic amino acids act as effectors which bind to the TyrR protein to form an active regulatory protein.  Acts by binding specifically to TyrR boxes in the promoter region of the target genes.
What are the official names of this protein?
HTH-type transcriptional regulatory protein TyrR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXD_SALEP
Sequence: MVFRIASSPYTHNQRQTSRIMLLVVIAALPGIAAQTWFFGWGTLFQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDMLDTLRMIFSGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGVGWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLSGATMLGAFFILTDPVTASTTNHGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CPFC_SYMTH
Sequence: MEKTAVLLVNLGTPSAPEPDAVRPYLAEFLGDWWVIDKPRWQWLPILHGIILRVRPPRVAKIYQKIWLPEGSPLLHYSRLQQAALQQRLEPEGIRVALGMTYGQPSVKSALEELRGWGVRRLLVLPLFPQYSSTTTAAVWSKVQKALDGWRDLPEQIFIRDFPTHPKYLAFLTERISGYIAEKGRPDALVLSYHSIPQAYTASGDDYAAQCESTTDAVRDRFPDLKIVMGYQSKFGNDPWLEPATDEVLRELVRTGHRHVAVMAPGFAADCIETLHELEVEYAEEFVKAGGERYDYLPAANDHPLFIDCLEDLVRRHLPR
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPP4_ASPFN
Sequence: MKYSKLLLLLVSVVQALDVPRKPHAPTGEGSKRLTFNETVVKQAITPTSRSVQWLSGAEDGSYVYAAEDGSLTIENIVTNESRTLIPADKIPTGKEAFNYWIHPDLSSVLWASNHTKQYRHSFFADYYVQDVESLKSVPLMPDQEGDIQYAQWSPVGNTIAFVRENDLYVWDNGTVTRITDDGGPDMFHGVPDWIYEEEILGDRYALWFSPDGEYLAYLSFNETGVPTYTVQYYMDNQEIAPAYPWELKIRYPKVSQTNPTVTLSLLNIASKEVKQAPIDAFESTDLIIGEVAWLTDTHTTVAAKAFNRVQDQQKVVAVDTASNKATVISDRDGTDGWLDNLLSMKYIGPIKPSDKDAYYIDISDHSGWAHLYLFPVSGGEPIPLTKGDWEVTSILSIDQERQLVYYLSTQHHSTERHLYSVSYSTFAVTPLVDDTVAAYWSASFSANSGYYILTYGGPDVPYQELYTTNSTKPLRTITDNAKVLEQIKDYALPNITYFELPLPSGETLNVMQRLPPGFSPDKKYPILFTPYGGPGAQEVTKRWQALNFKAYVASDSELEYVTWTVDNRGTGFKGRKFRSAVTRQLGLLEAEDQIYAAQQAANIPWIDADHIGIWGWSFGGYLTSKVLEKDSGAFTLGVITAPVSDWRFYDSMYTERYMKTLSTNEEGYETSAVRKTDGFKNVEGGFLIQHGTGDDNVHFQNSAALVDLLMGDGVSPEKLHSQWFTDSDHGISYHGGGVFLYKQLARKLYQEKNRQTQVLMHQWTKKDLEE
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DppIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2563_YERPE
Sequence: MDMTNAQRLILSNQYKMMTMLDPENAERYRRQQTIVERGFGLQMRELDRDFGEMSEDTCRTIINIMEMHHALQVSWGNLKEKQDLDERRISFLGFDAATESRYLSYVRFMVNTEGRYTHFDSGTHGFNSQTPMWDKYQRMLAIWQSCPRQYHLSAVEISQIINA
What are the official names of this protein?
UPF0304 protein YPO2563/y1624/YP_2374.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: ACPS_STRZT
Sequence: MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSISHTDQFVTASVILEENHES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPO7_MOUSE
Sequence: MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDEDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN
What is the function of this protein?
Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1.  Acting autonomously is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5 (By similarity).  In association with KPNB1 mediates the nuclear import of H1 histone and the Ran-binding site of IPO7 is not required but synergizes with that of KPNB1 in importin/substrate complex dissociation (By similarity).  In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones (PubMed:11493596).
What are the official names of this protein?
Importin-7, Imp7, Ran-binding protein 7, RanBP7.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCA_XANCB
Sequence: MKIYLVGGAVRDALLGQPAGDRDWVVVGADQAQMQALGYKPVGKDFPVFLHPRSGEEYALARTERKSGRGYRGFVVDADPSVTLEEDLLRRDFTINAIARDEASGEVFDPYGGVRDLQQRVLRHVGPAFVEDPVRVLRAARFMARLAPLGFGIAPETAALMREMADSGELDSLVPERVWQELRRVLGSAQPSAFLRTLHDTGALRAILPELDALYGVPQRAEFHPEVDTGVHQEMVSDMAARLAPGDALVGFAALTHDLGKALTPPEQWPRHVMHEQRGVAPLQALCERLKVPQDYRQLAVTACREHLNVHRLPELRDRTVHELLVRCDGFRRPERIAQLALVCEADKRGRLGSEEAAYPQGPELQRVHAAALAINARDLAADGLQGPQIGEALASARIAAIAQARSLRQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: 36020_ASFB7
Sequence: MPTPLSLQALAKKVLATQHISKDHLYFEILWFMVAFFDAYSL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-20R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: Y05K_BPT4
Sequence: MLTREQFEKIIKLAHDIEIDSYQLAVEHCEGYSYDGIEAAKRDLDKSKAKLVQYLEMIRWNNEN
What are the official names of this protein?
Uncharacterized 7.6 kDa protein in mobD-ri intergenic region.
Protein: VIF_HV19N
Sequence: MENRWQVVIVWQVDRMRIRTWNSLVKHHMYVSKKAKGWFYRHHYESRHPRVSSEVHIPLRDATLVVRTYWGLHAGEKDWQLGHGVSIEWRQKRYSTQIDPNTADHLIHLYYFDCFSESAIRKAILGEIVSPRCEYPAGHNKVGSLQYLASKALVTPTRKRPPLPSVGKLAEDRWNKPQKTRDHRENPTMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: HIS8_VIBCH
Sequence: MEKLARQQIQALTPYLSARRIGGSGDVWLNANESPFNNEYKTDFARLNRYSDCQPKAMIQAYANYAGVQPEQVLTSRGADEGIELLIRAFCEPNQDVILFCPPTYGMYAISAETFGVERKKVPLTTDWQLDLPSIEANLDRVKLVFVCSPNNPTGNLVKRADIIKLLEMTQDRAIVVMDEAYIDFCPEASTVDLLAQYPNLAILRTLSKAFALAGLRCGFTLANAELINVLLKVIAPYPVPVPVAEIAVQALSPAGLARAKYQVLDLGANRAYLQVGLSMVPGVQVFEGWGNYLLVKFPDGDALFKAAWEHGIILRNSPIENCVRISVGNREECEKTVAFIRNYYQ
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: LEU3_BEUC1
Sequence: MTRSIDLAVVAGDGIGPEVVAEGLKVLDAALAGTDVTVRTTAYDLGAARWHATGETLTDEDLAALAQHDAILLGAIGDPGVPSGVLERGLLLKLRFAFDHYVNLRPSRLYPGVATPLAKGGDVDFVVVREGTEGPYVGNGGAIRVGTPHEIANEVSVNTAFGVERVVRDAFARADARPRKKLTLVHKHNVLVHAGHLWRRTVEAVGAEFPDVAVDYLHVDAATIFLVTDPARFDVVVTDNLFGDILTDLAAAITGGIGLAASGNINPDRAFPSMFEPVHGSAPDIAGQGKADPTATVLSVALLLEHLGLTEQAARITAAVESDIVERGSAVRSTAEVGDALAARVAG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURF1_XENTR
Sequence: MALPGVTKLLLLPGVRAQLLNTPVRLSHWATPGRCTKSCHAYLQKNLRFCTTRSFSSVSPAAESSEDTVLKWLLLLIPVATFSLGTWQVQRRSWKLKLIQEMEARVSGKPIPLTTDPMEIKELEYRPVKVRGHFDHSKELYILPRTLVDPEREAREAGQLASNTQSGAQVITPFYCSDLGITILVNRGFVPKKKVNPETRPKGQVSGEVELVGIVRLNETRKPFVPHNDPSRNLWHYKDLSAMAQVVGAEPILIDADRGSTVPGGPIGGQTRVTLRNEHMQYIVTWYGLCAATTYLWCKKFIRKVAL
What is the function of this protein?
May play a role in mitochondrial respiratory chain complex IV assembly.  Probably involved in the biogenesis of the COX complex.
What are the official names of this protein?
Surfeit locus protein 1.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: HSP1_NOTEU
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRSRGRRRRRSRRGRRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DSBB_XANC5
Sequence: MNPFRWSFRAQFLLGFLACAGLLAYAIYVQLHLGLEPCPLCIFQRIAFAALAMFFLLGALHGPRAAAGRKVYGVLSFIAAGVGMGIAARHVWVQIRPKDMMSSCGPPLSFLSETMGPFEVFRTVLTGTGDCGNIDWRFLGLSMPMWSMVWFVGLALWALYAGFKARRSSVHH
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3A_METBF
Sequence: MARKKVQRKLDGWKSKEWYNIEAPAYLNRAIVGNTMAGDPSLLVGRNIETTVGELTNDMTKNNTKVILRINNVVGDVATTDLMGHELTTDYIRSIVKRQTSRIDANIDVKTKDGYIIRVKPTCFTIKRARSSQIKAIREMMVNIVAKRASEADFETFMQEAILGRLSAAIYRQAKFIYPLRRVEIRKTQVEAAPAPAASAAPEPAAA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: RL3_BRUC2
Sequence: MRSGVIAQKLGMTRVYNDAGEHVPVTVLRMENCHVVAQRTVEKNGYTAVQLGVGMAKVKNTSKAMRGHFAKAEVEPKAKLAEFRVSPDNLLEVGVEITAEHFVAGQKVDVTGTSIGKGFAGVMKRHNFGGHRASHGNSITHRSHGSTGQRQDPGKVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRGLILVRGAVPGSKGAWILVRDAVKASLPENAPKPAGLRAGAKAEAAATEGAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SDHF3_MAGO7
Sequence: MRASMVRRMAAAASSSASSSLRPAPLALLPPIPLYRRLLRAHRKHLPAEMRLLGDEYLKSEFRAHRNIDNPAHLIGFLTEWQLYAQQVEGESWLGEKIDQAKVEKLSEQQVGQLYELMMAIKSRREGGEGEGQESP
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DYL3_CHLRE
Sequence: MAAKVDIFAANLPNLTDEEMDMCRKAFAMFDKDGSGTIDTKELRTALSALGQNPTEEDMFVMISQVDQDGSRCIEFKEFVRVIQINKQMSAKDADEADTLDAFVALGGNLDKTGRILVDKLRSICEEFELTVNVDRLVKDADRDLNGFLSYDEFRALLS
What is the function of this protein?
May be involved in the calcium-mediated regulation of dynein motor function.  Binds 1 mole of calcium.
What are the official names of this protein?
Dynein 18 kDa light chain, flagellar outer arm.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: UBIA_BLOPB
Sequence: MSNRLFFIKKCYNLAQLMRINQPIGFFLLLWPTLWGLWLSHKGIPDKVVLIVFVAGALCMRSAGCIINDYVDYDIDGHVQRTKTRPLPSGMIRKKEALVALSILLFIAFILVLSLNFITIFLSVVALILSWIYPYLKRYIYFPQVMLGLLFSWPILMAFTAINNPINSTAWLLFLMNTVWTIVYDTQYAMIDREDDIYVGIKSSAVLFGDMDKFLIGILQLCIVFILGIIGWKERFTVVFYFFSLFGVIILFMWQQILINKRKRIRYFQAFLSNNYVGMLVFIGIASSFH
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TORD_COLP3
Sequence: MSHVSQETAQEISEEREARAIVYNFLSSLFAKEVTSDLVAQLTSAQGQSFLKSLALDPSLSASVNEINTKLVKLNSKESLLELAADFCGLFLVDGRTSVSPYAGQYLSVEQGGEPSEKLSNAAINESGSKSKKNKAQLFGELHQQMTEFLTDNKLQIHSDFPEPGDHIAVILAYIAHLCVTSGSEQQLNFINSYLMTWLSDFTQQVNKHDHGQFYCFVADLTFEWLKVDTEFLLSD
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_RHIE6
Sequence: MGGTPELKLYNTLTREKSVFAPIDPNNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGESHVTYARNITDVDDKINARALRDHPGLPLNEAIRAVTEKTETQFHADVAELGCLEPNVEPRATDNIEEMIEIIEKLISNGHAYVASGEVLFDTKSMADYGQLSKRPLDEQQAGARVAVDAHKKNPGDFVLWKLSSHNEPGWDSPWGRGRPGWHIECSAMSRRYLGDIFDIHGGGLDLIFPHHENEIAQSRCAHGTEVMANVWMHNGFVQVEGRKMSKSEGNFVTIHDLLHTETFGGRKWPGAVLRLAMLMTHYREPIDFSIKRLEEAERLLAKWPATEPGDAKPDEAVMNALADDLNTVAAVQALHALAQAAHTDAAVGATFAATAFLLGVLPKKAEIDEAVAAAVDALVAIRLEMLKAKNFAEADKIRDELTAKGIQLKDGKDAATGERVTTWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_POLNA
Sequence: MQTNLLKPKTINVEQLGANRAKVTLEPFERGYGHTLGNALRRVLLSSMVGHAATEVTIAGVLHEYSSIDGVQEDVVNILLNLKGVVFKLHNRDEVTLSLRKDGEGPITAADIQTPHDVEIVNPDHVIMNLSHGGKIDMQIKVENGRGYVPGNVRRYGDESPKSIGRIVLDASFSPVKRVSYTVESARVEQRTDLDKLVLEIETNGAVTAEDAVRASAKILVEQLAVFAQLEGNELGAIINDPAPRSSQQFDPILLRPVDELELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMRLESWPPAGLDKR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: Y539_TREPA
Sequence: MTSLQVLSIISSFLTQGLPHPPHVAADSHYISKKDSISASVGRLTSLLPCLCALHAYGVGHRPFVIVDIFYAE
What are the official names of this protein?
Uncharacterized protein TP_0539.
Protein: RECA_CLOBA
Sequence: MANIDINKLKAIENAMGQIEKQFGKGSVMKLGEDSVLNIDAISTGCLDLDIALGIGGVPKGRIVEIYGPESSGKTTIALHIAAEAQKKGGAVGFIDAEHALDPSYARNLGVDTENLIVSQPDTGEQGLEIAEALVRSGAIDVIIVDSVAALVPKAEIEGEMGDSHIGLQARLMSQALRKLAGTISKTNCIAIFINQLREKVGVMFGSPETTTGGRALKFYASVRLDVRRIDSIKQGDGIVGNRTRIKVTKNKVAPPFKQAEFDIMYNEGISREGNIVDVGVKEEIVQKSGAWFSYGDIRLGQGRENAKQYLKENPEVALDIENQIREKHNLPLMDAVIKETSQEVKGKENKEQSDK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.