PharMolix/UniProtQA huggingface dataset:
Protein: RL10_SALCH
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: COAD_SHEPC
Sequence: MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTAHLDNVDVVGFSGLLVDFAKEQKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVAAALAAKLTSINT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_RICBR
Sequence: MTKKIIAKKIIALVGRPNVGKSTLFNRLSMRKKAIVHDLPGVTRDRKYTDGRIGSFEFSLIDTPGLEENPDSFGKRLMEQTTKAINEADLICFMVDSRSGILPDDKLLSDFVRKYNKPAVLVINKCEKAFDFDKEYYKLGFDSMVAISAEHGTGMIDLYDEIIAKLPEEDSAEAEIHDPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKGNHIKLIDTAGLRKKATITESLEKLSASDAINSIKFANTVILMIDALSPLKQQDLNIASHVANEGRSIVIVVNKWDLIKESEKEAFKEEFYYQINTTLPQVKGVPALFISAKNKQNIADVLDSCIKIYKTWNKKITTSKLNEWLNFTTEAHPLPLQKGGKRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFNYIKTKNPYV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GLHA_MOUSE
Sequence: MDYYRKYAAVILVMLSMFLHILHSLPDGDFIIQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNARVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_BACVZ
Sequence: MKLHELKPSEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRPGFEGGQMPLFQRLPKRGFTNINRKDYAIVNVDKLNGFAEGTEVTPELLLETGVISKLNAGVKILGNGKLEKKLTVKANKFSASAKEAVEAAGGTAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RSD_ECOLU
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBD2_DROME
Sequence: MAYLLSFGIVAALFLASISLYRYGNIPRQHILVTLSVLTAWCFSFLIVFTIPLDVTSTLYRQCVEEHRPTPAPNVTNTSSATVGPPPQCQEPWGMVPASVFPNLWRIIYWSSQFLTWLIMPLMQSYLKAGDFTVKGKLKSALIENAIYYGSYLFICGVLLIYIAVKGESLDWQKLKAIASSASNTWGLFLLILLLGYALVEVPRSLWNNAKPGFALQYAYFKAAKLSTEKAEAEEHVDDILESLQGLSRVIPNNHELRPCLETILRKVPIELQERASRNFARTGGSGMGATSSTILPSEKALVRIHKQVIKSLQTLQRTEALWSVQVQTVLHLEDVAKNIHSSDRRFKSEFPRQRTQLERICYSASLQWYWECLLKAPFLKTMCVLTATMSAMVVWSELTFFSRHPVLSIFANVIYVAKESYDFFTIEVFSMVVLCYFFYCTYSTILRIRFLNLYYLAPHHQTNEHSLIFSGMLLCRLTPPMCLNFLGLIHMDTHIIPNRIMETVYTQIMGHMDVIGIISNGFNIYFPMCMLAFCLATWFSLGSRALNALGFQQFLQNETIATELVQEGKDLIAREKRRRQRAEEAMARRRDFNRTDQVLGSDYLSKYRSGGPGGLTSSRTPADGLLRDGDGSFDYAAVASSSALGVPRSLSEEINDRFGVSTQVQVGFRDPDYEAETDGRIVGPPPRGLFDDV
What are the official names of this protein?
LMBR1 domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FMP52_ASPNC
Sequence: MANVALLGCTGMVGSHILTHLLGNSSVARIDTISRRTPQPATAAPQEKLTTFVSDDSSKWASQLSSLTPTPDIFISAFGTTRGAAGGFENQYKIEHGLNVEMARAARDAGTKVYVLISSTGADKNSSFGYPRMKGEIEEEVKAMGFDRTIILRPGLISGERQESRPAEAVMRGFAGLVGKIHSGLKDGWAQDADVIAKAAVNAGVKALNGEVPAGSEKVWVMYGKDIIQYGKGQ
What are the official names of this protein?
Protein fmp52, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: MOAC_PELTS
Sequence: MSGLTHLDERGQARMVEVGGKEATRREAVARGEVSMRPETLELILGGKVPKGEVFGVARVAGIMAAKKTPELIPLCHPLMLTGIDVQFRPDPERSRVEIEARVRTTGQTGVEMEALTAVTVAALAIYDMCKAVDREMVIGAVRLVHKSGGKSGVFERKGEEAWTEMQGTE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PTGES_HUMAN
Sequence: MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
What is the function of this protein?
Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway.  Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli (PubMed:18682561, PubMed:10377395, PubMed:12672824, PubMed:12460774, PubMed:10869354, PubMed:12244105).  Plays a key role in inflammation response, fever and pain (By similarity).  Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2 (PubMed:12244105, PubMed:12672824).  In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively (PubMed:12672824).
What are the official names of this protein?
Prostaglandin E synthase, Glutathione peroxidase PTGES, Glutathione transferase PTGES, Microsomal glutathione S-transferase 1-like 1, MGST1-L1, Microsomal prostaglandin E synthase 1, MPGES-1, p53-induced gene 12 protein.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.
Protein: RIR3_SALTY
Sequence: MATTTPERVMQETMDYHALNAMLNLYDKAGHIQFDKDQQAIDAFFATHVRPHSVTFASQHERLGTLVREGYYDDAVLARYDRAFVLRLFEHAHASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEHFEDRVTMVALTLAQGDETLATQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFRLAKENAQMALFSPYDIQRRYGKPFGDIAISERYDELIADPHVRKTYINARDFFQTLAEIQFESGYPYIMFEDTVNRANPIAGRINMSNLCSEILQVNSASRYDDNLDYTHIGHDISCNLGSLNIAHVMDSPDIGRTVETAIRGLTAVSDMSHIRSVPSIAAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHAVHTSMRLARERGKTFAGFAQSRYASGDYFTQYLQDDWQPKTAKVRALFARSGITLPTREMWLKLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKIEIRKEGKTGRVYYPAPFMTNENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKSLYYIRLRQLALEGTEIEGCVSCAL
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  R1E contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase 2 subunit alpha, R1E protein, Ribonucleotide reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: NA12_ANESU
Sequence: GVPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKKHGPTIGWCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation.  Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals.  This toxin is highly potent at mammalian Nav1. 1/SCN1A (EC(50)=6. 01 nM) and Nav1. 2/SCN2A (EC(50)=7. 88 nM) (PubMed:15169781).  It has also great activity on Nav1. 5/SCN5A (EC(50)=49. 05 nM), Nav1. 4/SCN4A (EC(50)=109. 49 nM) and Nav1. 6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1. 3/SCN3A (EC(50)=759. 22 nM) (when measured as the increase in the slow component) (PubMed:15169781).
What are the official names of this protein?
Delta-actitoxin-Avd1c, Delta-AITX-Avd1c, ATX-II, ATX II, Anemonia sulcata toxin 2, As2, Neurotoxin 2, Toxin II.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: ROC4_ORYSJ
Sequence: MQFPFSGAGPGVFTSSPALSLALADAVAGRNSGGGGKMVTAAHGGVGGGGGGGRAKARDALEVENEMSRSGSDHLDVVSCGDAGGGGGDDDDDEDAEHGNPPKRKKRYHRHTPQQIQELEAMFKECPHPDEKQRAELSKRLGLEPRQVKFWFQNRRTQMKMQLERHENSLLKQENDKLRSENLSIREATSNAVCVGCGGPAMLGEVSLEEHHLRVENARLKDELSRVCALAAKFLGKSISVMAPPQMHQPHPVPGSSLELAVGGIGSMPSATMPISTITDFAGAMSSSMGTVITPMKSEAEPSAMAGIDKSLFLELAMSAMDELVKMAQMGDPLWIPGASVPSSPAKESLNFEEYLNTFPPCIGVKPEGYVSEASRESGIVIIDDGAALVETLMDERRWSDMFSCMIAKASTTEEISTGVAGSRNGALLLVSDEHSVMQAELQVLSPLVPIREVKFLRFSKQLADGVWAVVDVSADELMRDQGITSASSTANMNCRRLPSGCVLQDTPNGFVKVTWVEHTEYDEASVHPLYRPLLRSGLALGAGRWIATLQRQCECLALLMSSIALPENDSSAIHPEGKRSMLKLARRMTDNFCAGVSTSSTREWSKLVGLTGNIGEDVHVMARKSVDEPGTPPGVVLSAATSVWMPVMPERLFNFLHNKGLRAEWDILSNGGPMQEVTSIAKGQQNGNTVCLLKASPTKDKQNSMLILQETCADASGSMVVYAPVDIPAMHLVMSGGDSSCVALLPSGFAILPAGPSIGADHKMGGSLLTVAFQILANSQPSAKLTVESVETVSNLISCTIKKIKTALHCDV
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein ROC4, GLABRA 2-like homeobox protein 4, HD-ZIP protein ROC4, Homeodomain transcription factor ROC4, Protein RICE OUTERMOST CELL-SPECIFIC 4.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR12_NEPOL
Sequence: MPTIQQLVRAQRKRIVKKTKSPALCACPQRRGVCTRVYTTTPKKPNSALRKVARVRLSSGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTLDTAGVKERKQSRSKYGVKRVTKK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YJR5_YEAST
Sequence: MFLTSPFESCIVLSSLIAGLLFSLSTGFVGILGVFASLFETELSVSPKRLSLSSLSWPKTFWALLSSVEGVSWESSLFACIVGCCFAVTVIASLSASRVFGTVASSFRDSSCCCDSSPAVSVLATPATAALALLSLLLSLPCWSTSTEAFTVDPSPSVFSMLANRITIGL
What are the official names of this protein?
Putative uncharacterized membrane protein YJL175W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BTUF_SALTY
Sequence: MAKQMFRALVALLLTLPVWLYAAPRVITLSPANTELAFAAGITPVGVSSYSDYPPEAQKIEQVSTWQGMNLERIVALKPDLVVAWRGGNAERQVNQLTSLGIKVMWVDAVTIEQIADTLRQLAAWSPQPEKAQQAAQTLLNEYAALNAEYAGKAKKRVFLQFGMNPLFTSGKGSIQHQVLTTCGGENVFADSRVPWPQVSREQVLARHPQAIIVAGKAGEILKIEQYWGNLLKIPVIPLNSDWFERASPRIILAAKQLCNALSQVN
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity).
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RSMH_SULDN
Sequence: MQTIPHVPVLYREVLEQFKNIKNGIVIDCTMGYGGHTSLILDANPNIKLIAIDQDQSAIDFSTKRLEPYGDRVVIKKGRFSTIIKEILKEYDISDIRGILADIGVSSLQLDKKERGFSFFSENLDMRMDEDAPLNANIVINEYSSHELQRVLLEYGELRNYKQIASFIVSNRPFYSAKELSDALRHLMPSGKKIHPATLLMQAIRIEVNNELGELESLLDTIQERKFLDTKVAIISFHSLEDRIVKNRFNEWRASCICPQEAMRCTCTNDNSLGNILTKKPIIAQMDEIQANPRSRSAKLRVFEMKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_CAUVC
Sequence: MTKAASGDTKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKIAFVKSKDGVPTPREICEVLDDYVIGQGHAKKVLAVAVHNHYKRLNHASKNNDVELAKSNILLVGPTGTGKTLLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIVLKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIISARGAAKSIGFGAKVTDPEERRTGEILRNVEPDDLQRFGLIPEFIGRLPVVATLEDLDEAALVKILTEPKNAFVKQYQRLFEMENIGLTFTEDALHQVAKKAIARKTGARGLRSIMEGILLETMFELPTYEGVEEVVVNAEVVEGRAQPLLIYAEKKGGAASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ANAO2_ANAOC
Sequence: LSVCFLILFHGCLASRQEWQQQDECQIDRLDALEPDNRVEYEAGTVEAWDPNHEQFRCAGVALVRHTIQPNGLLLPQYSNAPQLIYVVQGEGMTGISYPGCPETYQAPQQGRQQGQSGRFQDRHQKIRRFRRGDIIAIPAGVAHWCYNEGNSPVVTVTLLDVSNSQNQLDRTPRKFHLAGNPKDVFQQQQQHQSRGRNLFSGFDTELLAEAFQVDERLIKQLKSEDNRGGIVKVKDDELRVIRPSRSQSERGSESEEESEDEKRRWGQRDNGIEETICTMRLKENINDPARADIYTPEVGRLTTLNSLNLPILKWLQLSVEKGVLYKNALVLPHWNLNSHSIIYGCKGKGQVQVVDNFGNRVFDGEVREGQMLVVPQNFAVVKRAREERFEWISFKTNDRAMTSPLAGRTSVLGGMPEEVLANAFQISREDARKIKFNNQQTTLTSGESSHHMRDDA
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
11S globulin seed storage protein Ana o 2.0101, 11S globulin Ana o 2, Allergen Ana o 2, Anacardein, Cashew major protein, CMP, Legumin Ana o 2, Legumin-like protein Ana o 2.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: PAND_XANAC
Sequence: MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEDGSGIMSLNGGAARHVQVGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHSIPTQAA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_ECO5E
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILHAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEHQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RS20_LACLA
Sequence: MANIKSAIKRAELNKVANERNAQQKSAMRTLIKKFEAAPTEELYRAASSSIDKAASKGLIHANKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SLS1_TRYB2
Sequence: MISYPFFSLSPPGLVPPPMAVPPVEMYSGSFWNRMRKPLPLRTQVIRFTVVFVIVSFILAVALQITHERMPDPKVTKPLPDLGFELLTKISFLSVVTDVLIAFLSSLSFFTLWKLYLLHRHCVGSGEPELPCNIPGVSRFFLSVWLCKENCRIELRNVHTIAWIRFITSYALLLLFRSLVIVMTSMPTPVDKCQNPPKIENPVKNVILTVLTAGGGSIHCGDLMYSGHTVILTLHLMFHWIYGAMVHWSFRPVVTVVAIFGYYCIVASRSHYTDDVLVAIYLTIATFIAVGHNADGAPWQLQLFIRWLPCCGANSREVTEDSQPVMVAFKSEAVDELRERDDSAGLSCEVSTNEV
What is the function of this protein?
Bidirectional lipid inositolphosphotransferase capable of converting phosphatidylinositol (PI) and ceramide to inositol-phosphorylceramide (IPC) and diacylglycerol (DAG) and vice versa.  Direction is dependent on the relative concentrations of DAG and ceramide as phosphoinositol acceptors.  Does not function strictly as a SM synthase.  Essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential drug target (By similarity).
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase, Inositol-phosphorylceramide synthase, IPC synthase, Sphingolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FTSB_POLAQ
Sequence: MRIVIYSMLVLLIAIQYPLWLGKGGWLKVYEMEKQVELQEAKNSLLALRNAKLEGDVKDLKDGTRAIEERARVEHGLIKEGEFFVQILPADQSSADTAKASTVKQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ESXL_MYCTU
Sequence: MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIIRDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
What is the function of this protein?
Induces apoptosis of host cells (PubMed:25242740).  Is immunogenic with highly specific seroreactivity towards TB patients' serum (PubMed:27751956).
What are the official names of this protein?
ESAT-6-like protein EsxL.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS) (Probable). Secretion may depend on complex formation with EsxK (Probable).
Protein: Y908_BACHK
Sequence: MSENGLKEQITGKVEKTKGQVKEGIGEVTEDRKLKNEGKWDKTKGTIKEKVGKVKQKISDGLDNKE
What are the official names of this protein?
UPF0337 protein BT9727_0908.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: AROE_ACISJ
Sequence: MTAAADLYCVMGNPIAHSRSPWIHARFAQLTGQSLHYERRLVPLDGFAQALQSFAAEGGRGCNITVPFKLEAAQLATTRSERVQLAGAANTLVFDGGSIHADNTDGLGLVADITQGAGVPLAGRDVLLVGAGGAAAGVLGPLLRQHPRRIAVVNRTPARAQALVDSHAALAALQKTELLALDMQAPGADFDVIINATASSLEGGPVPVPASVLRPGSLAYDMMYGPAAQPFLDWATGHGATARDGLGMLVEQAAEAFLLWRGVRPPSAPVLQELRAAIAAGA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NDHM_PROMM
Sequence: MNETLLKCTTRHVRIFTARVENNDLVPDPNQLTLDLDPDNEFLWTESVTKEIQQRFAELVASHAGGELSDYNLRRIGSELEGTIRKLLQAGKLSYNPECRVLNYSMGLPRTPELL
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IDI_RHOCB
Sequence: MAEEMIPAWVEGVLQPVEKLEAHRKGLRHLAISVFVTRGNKVLLQQRALSKYHTPGLWANTCCTHPYWGEDAPTCAARRLGQELGIVGLKLRHMGQLEYRADVNNGMIEHEVVEVFTAEAPEGIEPQPDPEEVADTEWVRIDALRSEIHANPERFTPWLKIYIEQHRDMIFPPVTA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, Bacteriochlorophyll synthase 20 kDa chain, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_CITSI
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYVTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTAVWTDGLTSLDRYKGRCYNIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFVEKDRSRGIYFTQDWVSIPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKSIKFEFAAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.