PharMolix/UniProtQA huggingface dataset:
Protein: RELX_FELCA
Sequence: MLRLFLSHLLGVWLLLSLRARKIPAQEEVLKACGREFVRLQIRICGSLSWGKSSQQHREPRQAPAALPEIVSSSITSGAEALNGMLEYIPDLPQELKATLSEREPSFRELQPSLKDSNLNLEEVEKSILGRQNEAEDQSLSQLGRSRLDAHSRIKRSDYIRYSDRCCNVGCTRKELADLC
What is the function of this protein?
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.
What are the official names of this protein?
Prorelaxin, RXN.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TA2R7_GORGO
Sequence: MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLCIILLDCFTLVLYPDVYATGKEMRIIDFFWTLTNHLSIWFATCLSIYYFFKIGNFFHPLFLWMKWRIDRVISWILLGCVVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHASTKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISFLLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRYVSLKVIWKVMSILKGRKFQQHKQI
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 7, T2R7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DFB10_MOUSE
Sequence: MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLTRCYKFGGFCHYNICPGNSRFMSNCHPENLRCCKNIKQF
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 10, BD-10, mBD-10, Defensin, beta 10.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_CHRVO
Sequence: MLSLYNTLTRQKEAFKPIEPGKVSMYVCGMTVYDLCHIGHARMLAAFDVIYRWLKASGYDVNYVRNITDIEDKIIKRALERGITPEQLVEETIADMRQDAAALGLLPPTHEPRATHHVGGMVAMIEQLIANGKAYPAANGDVYYAVREFEGYGKLSGRTLDKLRAGERVEVDPNKRDPLDFVLWKAAKPGEPSWDSPWGKGRPGWHIECSVMSCHHLGEHFDIHGGGEDLQFPHHENEIAQSEGAHGHQYVNYWLHNGFINVDGEKMSKSLGNFFTIRDVLQHFDGEVIRFFIVRSHYRSPVNYTDSILNDAKHGLTRLYTALRGIELPTSDGIDWNHAYAARFKAAMDDDFGTSEAVAVLFELAGEVNKSRDPQLARLLKDLGGVLGLLTRDPEVFLQGGVGEGELSAEQVEALIQARKDARAAKDWAESDRIRDELTAKGIVLEDGAGGTIWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_ALBFT
Sequence: MTIKSDKWIRRMAQQHGMIEPFEPGQIRQDANGNKIVSYGTSSYGYDIRCAPEFKVFTNIHSTVVDPKNFDEKSFVDFHGDSCIIPPNSFALARTMEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGCAQVLFFESDEECETSYKDRGGKYQGQVGVTLPRA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: Y068_RICPR
Sequence: MKKLLLAASIVYFASACLAEEKTTPFLSNSDTKIKLEGFYLFESGYIKQNHLILFDKNVTDNRKKLGFYTEVAFAATITKTINDVIAGAKIVLQPTTKAKTAASYNGSHIFIETSYGKVELGSPVDASAKLRVTGNKVTAGTGGWYRYALLDGQYMRYNGLKPDFDTNVNFYLESYSNSFDQINEKTEKARRLNFFTPKMKGFQAGISYTPDTANTGGNKNINNLTLQSSGRNGISVSRTGIKTFALGNGETMTINQNIRDAFSAGLTYEHAISEDADLKLSMTGEYGKPARRLIHSKVDGTTKTIEVLNTYKLSNLKAYNLGAVFTYGNFSCGASYSNLGKSLTSKEYYKVGRNTYYYNGAVAYGQGPIKTSLAYLKASRYKNTVNAVSLATEYKIMPGLLPYAEISHFQAKGKPVYYPEAPSKTTRGTVGLIGTKLKF
What are the official names of this protein?
Uncharacterized protein RP068.
Protein: RS5_ECOUT
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: UPP_DESPS
Sequence: MSLHIADHPLVKHKLGLMRQNDISTKDFRALASEIARLLTYEAVKDLPTEKHIVDGWAGPVEVDRLKGKKITIVPILRAGLGMMDGVIDLIPSAKVTVVGFYRDEETLEPVEYYVKTASEMSERVALIIDPMLATGGTLIATIDTLKKAGSKKIKGLFLVAAPEGIKKVQDAHPDVEIYVAAVDERLNEAGYILPGLGDAGDKIFGTR
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: LYSM2_XENTR
Sequence: MADLSPVLQPHREGGSRYGYTMFPGLECESEAELSLSLARTKTRSYGSTASVAAPLSERYIEHRLSPSDTLQGIALKYGVTMEQIKRANKLFSTDCIFLRKSLNIPVISKKGSLFNGLGSLDSPENETQDNCNSPTKEPALAEAHTVSIPSSAKTNQPIVRSDEELSAKDFLQRLDLQIKRSTQAAQRLKEEDLRHDDSYATCSYQH
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 2.
Protein: CH60_KLEAK
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLEDELDVVEGMQFDRGYLSPYFINKPDTGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLVIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRKQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALVRVAAKIAGLTGQNEDQNVGIKVALRAMEAPLRQIVSNAGEEPSVVANNVKAGDGNYGYNAATEEYGNMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKGDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSC_SALTY
Sequence: MRVLLAPMEGVLDALVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELHHASRTPSGTPVRIQLLGQHPQWLAENAARATALGSYGVDLNCGCPSKVVNGSGGGATLLKDPELIYQGAKAMRAAVPSHLPVTVKVRLGWDSGDRKFEIADAVQQAGASELVVHGRTKAQGYRAEHIDWQAIGEIRQRLTIPVIANGEILDWQSAQACMATSGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVTLLQKYTRLEKQGDTGLYHVARIKQWLGYLRKEYIEATELFQSIRALNRSSEIARAIQAIKI
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: NPBW1_RAT
Sequence: MHNLSLFEPGRGNVSCGGPFLGCPNESNPAPLPLPQPLAVAVPVVYGVICAVGLAGNSAVLYVLLRTPRMKTVTNVFILNLAIADELFTLVLPINIADFLLRRWPFGEVMCKLIVAVDQYNTFSSLYFLAVMSADRYLVVLATAESRRVSGRTYGAARAVSLAVWALVTLVVLPFAVFARLDEEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICALYITLLCRLRAIQLDSHAKALDRAKKRVTLLVVAILAVCLLCWTPYHLSTIVALTTDLPQTPLVIGISYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLVSCRTA
What is the function of this protein?
Interacts specifically with a number of opioid ligands.  Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity).
What are the official names of this protein?
Neuropeptides B/W receptor type 1, G-protein coupled receptor 7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL30_GLAP5
Sequence: MAKTIKVTQTRSSIARLPKHKATLKGLGLRHIRHTVELEDTPAVRGMINQVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RBRA_DICDI
Sequence: MTDDEMYEDYDVDDDSAEESGNESLDDTEYDDAATQEFDFDENQPQRSLGKLTRQKSFEVLNKDDLFSESHKIIKEVKDVLSIPSEAAVSTLLRHMKWNKEKLIERYMENPEKLCIDAGVPNVMKLNATIVEKSGNVSCLICLEDYPPTQTFALICNHRYCLPCYKNYLEIKVSEGPECIYTPCPAPKCKVIVHQDAFKQIVSPEVFERFNNFILKSYVDDNPQVKWCPAPGCIYSIRCDRKERKEAVNCKCGFQYCFNCNDYEIGDHMPCPCSQVDKWLQKASDESENVTWMLANTKKCPECRSPIEKNGGCMHMTCRKNAGGCGFEFCWLCRGPWTEHGSTTGGYYNCNKYDKSKAKEDDDKAHDAKTELEAYMFYYHRYESHRNAMKIADEQRRNAHLKEQQILSKFDVRSADTKFLMEATEQLLKNRRVLQYSYVYGYYLDKKSQERNLFEYLQEDLEKHTNLLSTQYEQSLDKLEDYQAFIKWKEQVTNYTRITKKFLDNFVDGVAGGLVNTQIN
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase.  Appears to be required for normal cell-type proportioning and cell sorting during multicellular development.  In addition to being necessary for a normal percentage of prestalk cells and the organization of the slug, rbrA is also necessary for spore cell viability.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase rbrA, Ariadne-like ubiquitin ligase.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
Protein: PKS5_ALOAR
Sequence: MGSIAESSPLMSRENVEGIRKAQRAEGTATVMAIGTAHPPHIFPQDTYADFYFRATNSEHKVELKKKFDRICKKTMIGKRYFNYDEEFLKKYPNITSFDEPSLNDRQDICVPGVPALGKEAALKAIEEWGQPLSKITHLVFCTSCGVDMPSADFQLAKLLGLNTNVNKYCVYMQGCYAGGTVLRYAKDLAENNRGSRVLVVCAELTIIGLRGPNESHLDNAIGNSLFGDGAAALIVGADPIVGIEKPIFEIVCAKQTVIPDSEDVIHLHLREAGLMFYMSKDSPETISNNVEGCLVDIFKSVGMTPPADWNSLFWIPHPGGRAILDEVEARLKLRPEKFRATRHVLWEYGNMVSACVLYILDEMRNKSAADGLGTYGEGLEWGVLLGFGPGMTVETILLHSLPPV
What is the function of this protein?
Catalyzes the iterative condensations of 8 molecules of malonyl-CoA to produce aromatic octaketides, SEK4 and SEK4b, the products of the minimal polyketide synthase for the benzoisochromanequinone actinorhodin.  May be involved in the biosynthesis of the octaketide barbaloin.
What are the official names of this protein?
Octaketide synthase 3, OKS 3, Polyketide synthase 5.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: OPSD_SARPI
Sequence: MNGTEGPFFYIPMSNATGLVRSPYDYPQYYLVPPWGYACLAAYMFLLILTGFPVNFLTLYVTIEHKKLRSPLNYILLNLAVADLFMVIGGFTTTMWTSLNGYFVFGRMGCNIEGFFATLGGEIALWSLVVLSMERWIVVCKPISNFRFGENHAVMGVAFSWFMAAACAVPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVIYMFVVHFTCPLTIITFCYGRLVCTVKEAAAQQQESETTQRAEREVTRMVIIMFVAFLACWVPYASVAWYIFTHQGSEFGPVFMTIPAFFAKSSAVYNPVIYICLNKQFRHCMITTLCCGKNPFEEEEGSTTASKTEASSVCSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: CH60_MYCPV
Sequence: PYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKITETLLKSAKEVETKDQIAATAAISAGDLQIGELIAEAMDKVGNEGVITVEESQTFGL
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, 65 kDa heat shock protein, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VU54_HHV7J
Sequence: MESCYVVWSSYFLQLKLTAPILLKPREIRCLRTGLSILSQQSTFVCMCRDEGSFTAAYFTYIDLRDCGNVTLAVQNISDVDLDLKQFPLIINLFAFFLPSINLVSLPVQIVERMEHNYIPHGECRAQFILYGSQTKLRAHIKRIRWTELQHEEPTHYMYACEFWIDLQTTPPDQIFNSAKVEFISSRNVYFKQIMLHEKILVIRASYENNYLLNPDNFPSDIFFQVNFIQTIPHIVMERNQEPVMTYDGTCITVGSTKNINSNTTDPFSCTFPTFFDSKQKFAGLFIPRLINGISLNTFTWKERTHLQVTMRAYKKNCRIDYSQELGKLIFLPSQIVTHDQSNIDFGWTETSRILISNQNNQISVFRSETTPVADSPVLSTVPNITAATNVSINLNSLHLNIAKEHLVPVRYRMRTDNLRTFLPITALPHTLTVLEGNIGLQTVPCPSGNRDINA
What are the official names of this protein?
Protein U54.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL82 family.
Protein: NU4C1_SYNP2
Sequence: MDSLQIPWLTTAIAFPLLAALVIPLIPDKEGKTIRWYTLGVALTDFALLVTAFWQNYDLGRTEFQLTENFAWIPQLGLNWSLGVDGLSMPLIILATLITTLATLAAWNVTKKPKLFAGLILVMLSAQIGVFAVQDLLLFFIMWELELVPVYLLISIWGGKKRLYAATKFILYTALGSVFILASTLALAFYGGDVTFDMQALGLKDYPLALELLAYAGFLIGFGVKLPIFPLHTWLPDAHSEASAPVSMILAGVLLKMGGYGLIRLNMEMLPDAHIRFAPLLIVLGIVNIVYGALTAFGQTNLKRRLASSSISHMGFVLVGIASFTDLGMNGAVLQMLSHGFIAAALFFLSGVTYERTHTLMMDEMSGIARLMPKTFAMFTAAAMASLALPGMSGFVSELTVFLGLSNSDAYSYGFKAIAIFLTAVGVILTPIYLLSMLREVFYGKGSQAPLSLAAGEDAKPREIFVAVCLLAPIIAIGLYPKLATTTYDLKTVEVASKVRAALPLYAEQLPQNGDRQAQMGLSSQMPALIAPRF
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4 1, NAD(P)H dehydrogenase I, chain 4 1, NDH-1, chain 4 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: BMI1_PONAB
Sequence: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.  The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A.  In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
What are the official names of this protein?
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MURG_RHIME
Sequence: MDKGIILLAAGGTGGHLFPAEALAHELKATGYSVHLVTDSRAERFTGKFPADEIHVVPSATIGSKNPVKLARSVWKLWTGLRAARRLIARLKPRAVVGFGGYPTVPPLLAATGMGIPSIIHEQNAVMGRANKMLASRVKAVAGGFLPEGTGAFAAKTVATGNPVRPAVLKAAGVPYAPAAGDAPFHLVVFGGSQGAQFFSKAVPQAVCRLDDALRQRLKVTQQARPEDREGVIAVYEKLGVPAEVSPFFTDMAGRIASAQLLICRSGASTVSEISVIGRPAILVPYPYALDHDQAANAAALAAKGGARVIAQVELSAERLAGILADAMSNPDALAQMAAGARQTGKPDAARLLALLVEAIASGSTVAKFKETRS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FABH_PARDP
Sequence: MRRAIVRGTGHYLPERVVENSWFEDKLDTSDEWIRARTGIERRHFAAEDQRTSDLGILAAQAALADAGLEAAQIDAVIVATSTPDLTFPSVATMVQAGLGMRHGFAYDLQAVCAGFVYALANADALIRAGLADRVLLIGAETFSRIMDWTDRGTCVLFGDGAGAVVLEAAEGQGSSADRGILATDLNSDGQYRDLLYVDGGVASTGTAGHLRMQGNLVFRHAVEKLADTAHRALDRAGLTPDQVDWLVPHQANLRIIEATAKRMHLPMEKVVLTVADHGNTSAASIPLALSVANAEGRFKPGDLLVAEAIGGGLAWGSVVLRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_BLOFL
Sequence: MTIQSFAIEVQMSVDYLIQQFLDIGITKTKFDFITQSEKEILFRHMNVNKIAVFNKLFLQRKTHSTLNVSSTNGKSKKVKVEVRKKRVYMVPCSIRKSHVSNNTNILLVENDNSKDKYKSDDCNELSELVACDENKISSNENQVMCFISQKEKLDHFTIRQDYVRTNELVKDVNQDLDHQIRDRKGLSNSVCCDVLLNVQDEQHDDNNFSCGLSDDMAVSNNIPEHDKQKLENVRKNLTDRLRSTRTRNLSKLVKQNKHNNSKVCMIYESDKDEKLYVLPSSRVYKNKRKQSILVQSFNKPMQKTVRDVVIGETISVAELSNKMSIKSSSMIKMMMKLGLMVTINQNLDQETAQLVVEEMGHNAILRRENALEELIMHDNNNDYQNISSKLDNAKNDMGYKNRAPIVTIMGHVDHGKTSLLDYIRSTNVASSESGGITQNIGAYCVQLANNDMVTFIDTPGHEAFTDMRARGIQLTDIVVLVVAADDGVMPQTVEAIQYIRDGNLPVIIAINKIDKSVTNVERIKNELNSYGFIPEEWGGHTQFVNVSAVSGEGVNDLLDSILVQSEILELKSMHHGLAKAVVIESSLDRSRGPVVTVLVRSGELKCGDIVLCGTEYGRVRAMRDSLGFDVIKAGPSIPVELLGLSGIPGTGEWLVVVNNEKKAREVALYRKEKKREIKLARKSEKTIIENFNSMDIIKIKELNFIIKSDTQGSMEVICESLKKLSTNKMVMKILSASIGNVTETDAVLALSSHSRILAFNVKVDLSAKNIIELNHINIQYYSVIYSLLDEVKELISSTIAPQVDFKVIGIAKVHNIFQSPRYGTIAGCMVTQGVIKLHKQIKIVRNGIIMYKGVLDSLRHFKNDVSEVKIGVECGIGIKNYSDVCSGDIIEVLDKI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1378_LYSSC
Sequence: MEYSYPFSTDWSTEEIVDVVQFFEGIEQAHEKGIKREVMMAKYRRFKEIVPSQAEEKTIFREFEEASGYISYPVVKQTKEAADGTIIKIVPKKNR
What are the official names of this protein?
UPF0223 protein Bsph_1378.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PSB_METLZ
Sequence: MSQEHQDVKTGTTTVGIVFDGGVILATERRATMGNLIASKKAKKVHAITDKIGMTIAGGVGDAQQLVRIINVECNLYEIRRGQKISVGAAATILSNYLNQNRFSPYYVQLLVGGVDTSGPSVYSVDAAGGATLEENFVSTGSGSLTAYGVLEDRFKPNMTEEEAIELAVRALRAAMLRDSASGEGYNVVIITQEKFEYLPEDKIAGYLPPAK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBW_LISW6
Sequence: MATTHDKITLQLPAKPEYVSLGRLSLSGIASRAGFSYEAIEDLKIAVSEAITNSVKHAFKGEEDGEIIVEYLIYEDKLEVRVSDNGTSFDLESRKQEIGPYEVDEDAEMMRIGGLGLFLIETLMDDVKLYYDEGVSVVMTKYINEKQVEENAKSIST
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: PRTG_DICCH
Sequence: MALYGKKTDLSSASSGGYTGVADVYQLWHYHARGNGNIGDKPSYTLEQARDQITRGNITWNGEKVFGKSAALTYSFLQSVADSDMPDNFKGFVKFNAAQIQQTKLALQSWADVANVTFSEAKDGERATIQFGNYTLTPDGNTDNNSQAFGFYPGNWKWAGSAWFNYNQADNQRPDINEFGRNTLTHEIGHTLGLYHPGDYDASDGNPGYKDVTYAEDTRQFSIMSYWNEGYTGGDFHGYHAAAPHDIAAIQKLYGANMSTRTGDTVYGFHSNSGRDFYTATDSKTPLIFSVWDAGGNDTFDFSGYSANQRISLISGTFSDVGGLKAMVSIAAGAVIENAIGGSGHDVIVGNLSDNRIDGGAGNDVLYGDGGADILTGGAGKDIFVYAWEKDSLSSAPDTITDFQRGEDRIDLSAFNKNHDLRFVDNFSGKGNEVVLNWDSQSHQTNMWLHLSGHETADFLVNIVGAALQPSDVIV
What are the official names of this protein?
Serralysin G, Secreted protease G, ProG.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDI2_XENLA
Sequence: MLITVYCVRRDLSEITFSLEVDGDFELENFRALCELESGIPASDTLIVYAERPLTDNQRSLASYGLKDGDVVILRQKEAPETRPAAPFPGLDFSTIAVPGASSQPDPSQPQAPPPPPDTSSFPQGLDNPALLRQMLLANPHELSLLKERNPPLAEALLSGDLEKFTKVLQEQQQERARREQERIRLYSADPFDLDAQAKIEEDIRQHNIEENMTIAMEEAPESFGQVVMLYINCKVNGYPVKAFVDSGAQMTIMSQACAERCHIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLEKNVLVIGTTGTHTTFLPEGELPECARLAYGPGREEVPPEEIADRELAEVLQKSADEADQQKP
What is the function of this protein?
Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane.  Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1.  Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2.  Required for cellular survival following replication stress.
What are the official names of this protein?
Protein DDI1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Chromosome.
Protein: FAL1_NEUCR
Sequence: MADGGIDRKADEKIQFSTSKEVTVHPTFESMSLKESLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNQGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGDMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIELYYSTQIDEMPMNVADLIS
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase fal-1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.