PharMolix/UniProtQA huggingface dataset:
Protein: EXTL3_MOUSE
Sequence: MTGYTMLRNGGVGNGGQTCMLRWSNRIRLTWLSFTLFIILVFFPLIAHYYLTTLDEADEAGKRIFGPRAGSELCEVKHVLDLCRIRESVSEELLQLEAKRQELNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDAGLPPPKVTRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFAFGSYLDPLVKQAFQATVRANVYVTENAAIACLYVVLVGEMQEPTVLRPADLEKQLFSLPHWRTDGHNHVIINLSRKSDTQNLLYNVSTGRHVAQSTFYAAQYRAGFDLVVSPLVHAMSEPNFMEIPPQVPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLDQVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPHLLISSGCATRLFEALEVGAVPVVLGEQVQLPYHDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAMRRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEVAAEIPHRSGKAAGTDPNMADNGDLDLGPVETEPPYASPKYLRNFTLTVTDCYRGWNSAPGPFHLFPHTPFDPVLPSEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVQREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAILSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI
What is the function of this protein?
Receptor for REG3A, REG3B and REG3G, induces the activation of downstream signaling pathways such as PI3K-AKT or RAS-RAF-MEK-ERK signaling pathway (PubMed:28811323, PubMed:36240758, PubMed:35263589).  Required for the function of REG3A in regulating keratinocyte proliferation and differentiation (By similarity).  Required for the inhibition of skin inflammation mediated by REG3A through the activation of PI3K-AKT-STAT3 pathway (By similarity).  Required for the function of REGA and REG3G in glucose tolerance in pancreas (PubMed:36240758).  Expressed in microglia, is activated by nociceptor-derived REG3G in response to endotoxins, leading to the inhibition of kynurenine pathway to prevent endotoxic death (PubMed:35263589).
What are the official names of this protein?
Exostosin-like 3, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostosis-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus.
Protein: CH60_PSEMY
Sequence: MAAKEVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLAKSFGAPTITKDGVSVAKEIELKDAFENMGAQLVKDVASKANDAAGDGTTTATVLAQAIVNEGLKSVAAGMNPMDLKRGIDKATSAIVAQLKDLAKPCADSKAIAQVGTISANSDNSIGDIIAEAMDKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFINKPDTMVAELEGPLLLLVDKKISNIRELLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLESATLEHLGNAKRVVLNKDNTTIIDGAGAQADIEARVAQIRKQVEETSSDYDKEKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALQAIEGLKGDNEDQNVGIALLRRAVEAPLRQIVANAGGEPSVVVDKVKQGSGNFGFNAATDTYGDMIEMGILDPAKVTRSALQAAASIGGLMITTEAMVAEAADDKAPAMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_STRGG
Sequence: MNWDETGPETDEPTGPVLDDRLVDADADGEDTAVEAALRPKDLEEFVGQEKVREQLDLVLKAARARGATADHVLLSGAPGLGKTTLSMIIAAEMNAPIRITSGPAIQHAGDLAAILSSLQEGEVLFLDEIHRMSRPAEEMLYMAMEDFRVDVIVGKGPGATAIPLELPPFTLVGATTRAGLLPPPLRDRFGFTGHMEFYAPAELERVLHRSARLLDVGIDGEGAAEIAGRSRGTPRIANRLLRRVRDYAQVKAEGTIDRSIAMAALKVYEVDARGLDRLDRAVLGALLKLFGGGPVGLSTLAVAVGEERETVEEVAEPFLVREGLLARTPRGRVATPAAWAHLGLVPPQHGAKGQQGLFGA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ADA2B_RAT
Sequence: MSGPTMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPRGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQPVAGGVPTSAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPTWSALPRSGQGQKKGTSGATAEEGDEEDEEEVEECEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASGQWWRRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYCNSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: PKD2_DANRE
Sequence: MSSSRVRPQAPQSPAASASASPPPHEGIEMEKMHHEEVGLGVPDETPSSPPTSSSRQAWSRDNPGFEPEEGMMEADWPPESQGRRSVSTTSSSSSGGVPGNFSGISARINRGLYPTPPAQEHRSCGKRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQSLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQAAGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELERWESDDTMSQVSHHHHQATPIISSAQLRPRSSRPPSSLSNEGPDAAASGPAHL
What is the function of this protein?
Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B.  Can also form a functional, homotetrameric ion channel (By similarity).  Functions as non-selective, voltage-gated cation channel (By similarity).  Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (PubMed:25660539).  May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By similarity).  Required for normal temporal variation of the intracellular Ca(2+) levels in the heart (PubMed:23376035).  Plays a role in fluid-flow mechanosensation (By similarity).  Required for normal specification of the body left-right axis during embryogenesis, most likely via its role in ciliary Ca(2+) oscillations in Kupffer's vesicle (PubMed:15269167, PubMed:16216239, PubMed:16943304, PubMed:17360770, PubMed:23376035, PubMed:25660539).
What are the official names of this protein?
Polycystin-2, Curly up, Cup, Polycystic kidney disease 2 protein homolog, Transient receptor potential cation channel subfamily P member 2.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Cytoplasm, myofibril, sarcomere. Sarcoplasmic reticulum membrane. Apical cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle membrane. Note=Detected at the basolateral cell membrane and on apical, lumenal cilia in anterior, proximal pronephric ducts, and in intracellular vesicles in the posterior part of the pronephric duct. Detected on apical cell membranes on epithelial cells in the ear.
Protein: MURB_STRA3
Sequence: MIKTIQKELEGLDIRFDEPLKKYTYTKVGGPADYLAFPRNRLELSRIVKFANSQNIPWMVLGNASNIIVRDGGIRGFVIMFDKLSTVTVNGYVIEAEAGANLIETTRIARYHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILLSAQVLTPQGELKTIEARNMQFGYRHSVIQESGDIVISAKFALKPGDHLMITQEMDRLTYLRELKQPLEYPSCGSVFKRPPGHFAGQLISEAHLKGQRIGGVEVSQKHAGFMVNIAEGSAQDYENLIEHVINTVESTSGVHLEPEVRIIGESLL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_PI3H4
Sequence: MSITNSAIYTFPESSFSENGHIEPLPLKVNEQRKAVPHIRVAKIGNPPKHGSRYLDVFLLGFFEMERIKDKYGSVNDLDSDPGYKVCGSGSLPIGLAKYTGNDQELLQAATKLDIEVRRTVKAKEMIVYTVQNIKPELYPWSSRLRKGMLFDANKVALAPQCLPLDRSIKFRVIFVNCTAIGSITLFKIPKSMASLSLPSTISINLQVHIKTGVQTDSKGIVQILDEKGEKSLNFMVHLGLIKRKVGRMYSVEYCKQKIEKMRLIFSLGLVGGISLHVNATGSISKTLASQLVFKREICYPLMDLNPHLNLVIWASSVEITRVDAIFQPSLPGEFRYYPNIIAKGVGKIKQWN
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPD_ACHLI
Sequence: MTSTIYSDALFKLALKEDAIESIIEQFETFVSLARDYPDWIVLLDSPMIRNRVKNKMLTELGIFDALFMNFLMLLVRHHQVRLYEDIYEQWIAKSRLNQKIAYVQLYSAKPLSKKRLNQLKEEIQDYLPGLEIEFNQHIDPTLIEGVKMTYQGRSIERSLKKALDDMRTNI
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SARNP_PONAB
Sequence: MATETVELHKLKLAELKQECLARGLETKGIKQDLIHRLQAYLEEHAEEEANEEDVLGDETEEEETKPIELPVKEEEPPEKTVDVAAEKKVVKITSEIPQTERMQKRAERFNVPVSLESKKAARAARFGISSVPTKGLSSDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFGIA
What is the function of this protein?
Binds both single-stranded and double-stranded DNA with higher affinity for the single-stranded form.  Specifically binds to scaffold/matrix attachment region DNA.  Also binds single-stranded RNA.  Enhances RNA unwinding activity of DDX39A.  May participate in important transcriptional or translational control of cell growth, metabolism and carcinogenesis.  Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity).
What are the official names of this protein?
SAP domain-containing ribonucleoprotein, Nuclear protein Hcc-1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: HTPG_SHIBS
Sequence: MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEGEYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_HELPH
Sequence: MKLIASNKKAYFDYEILETLEAGLALLGSEVKALRQTRVNLKDNFVKIIKGEAFLFGVHISYLDTIHAYYKPNERRERKLLLHKKQLLKWQIEASKERLSIVGLKLYFNQRNRAKIQIALVKGKRLHDKRQSLKEKALNKEILADLKHHFKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYF1_YEAST
Sequence: MSAYIAMKGVITNVDENIRNDEDVAFEYEIQKTPQNILTWKRYIEYWKEEGRTDKQIRWLYERFCSQFVTDTSIWEDYIRWESTKEVVETSRIFWLFQRCLKSCVRDCDRICLSYLELAIEQYDLAMIRHALASSLMKMEREMHRKVWDPVIKFVEEKVLPLTQLDSTQEDEEESTDEAELINVLLVKGFTKGGFISEEISENGSRGDIWSSHILERYLKVAPQQKRNESLATLALTRDNITIKSVYEKYLPQDENSGKYLPSSELPFELNFNYLASLEKLGLDNQYEEFMRQMNGIYPDKWLFLILSLAKYYISRGRLDSCGDLLKKSLQQTLRYSDFDRIYNFYLLFEQECSQFILGKLKENDSKFFNQKDWTEKLQAHMATFESLINLYDIYLNDVALRQDSNLVETWMKRVSLQKSAAEKCNVYSEAILKIDPRKVGTPGSFGRLWCSYGDLYWRSNAISTARELWTQSLKVPYPYIEDLEEIYLNWADRELDKEGVERAFSILEDALHVPTNPEILLEKYKNGHRKIPAQTVLFNSLRIWSKYIDYLEAYCPKDANSSDKIFNKTKMAYNTVIDLRLITPAMAENFALFLQNHYEVMESFQVYEKTIPLFPPEIQYELWIEYLEVATSHQLSSLSPEHIRFLFEKALKNLCSNGIDCKTIFIAYSVFEERISGLISKSIEILRRGAVIGTVSVSTHLESRLQLWRMCISKAESTLGPSVTRELYQECIQILPNSKAVEFVIKFSDFESSIGETIRAREILAYGAKLLPPSRNTELWDSFEIFELKHGDKETYKDMLKMKKVLESNMLIDSASVSHEEGNINFVAAATSHAPNSHTLTQSTSSYSINPDEIELDI
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.  As a component of the NTC complex (or PRP19-associated complex), associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1, PRP19-associated complex protein 90, Synthetic lethal with CDC40 protein 1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZAPB_AERHH
Sequence: MHMSLEVLEQLESKVQSAVDNISLLKMELDELKEQNNKLQDENHQLRNEHVAWQERLRALLGKMDQMGESI
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: EFTU_RENSM
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISKVLYDKYPTLNEQRDFASIDSAPEEKQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLARQVGVPYLLVALNKSDMVEDEELLDLVEMEVRELLSSQEFDGDNAPVVRVSGLKALEGDPQWVKSVEDLMEAVDESVPDPIRDKDKPFLMPIEDVFTITGRGTVVTGRAERGTLAINSEVEIVGIRPIQKTTVTGIEMFHKQLDEAWAGENCGLLLRGIKREDVERGQVVVKPGSITPHTDFEANVYILSKDEGGRHNPFYSNYRPQFYFRTTDVTGVITLPEGTEMVMPGDNTEMTVALIQPIAMEDGLGFAIREGGRTVGSGRVTKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MA26A_MYCTT
Sequence: MARTLRYLLCGILALAAGSNAVPAARGSTRAAPAAEPSTSATTYEAEDAILSGTTVDTAQEGYTGSGYVTGFDEASDKITFEVESEATKLYDLSIRIAAIYGDKHTTVVLNGGASSDVSFPAGDTWVDVPAGQVLLNEGANTIEIVSNWGWYLVDSITLTPSAPRPEHQINRSLNNPSADASARALYDYLRSIYGKKILAGQQDLTWADYVTQQTGKTPALVSVDLMDYSPSRVERGTKGTSVEEAITHAERGGIVSALWHWNAPAGLYDTDEHPWWSGFYTDATDFDVAAALSSTDNANYTLLLRDIDAIAVQLKRLRDARVPVLWRPLHEAEGGWFWWGAKGPDPAKQLYALLYDRLVNHHGINNLIWVWNSLSPDWYPGDDTVDILSADVYAQGNGPMSTQYNQLIDLGKDKKMIAAAEVGAAPLPDLLQAYEAHWLWFAVWGDTFINNAEWNSPEVLKTVYTSDYVLTLDEIQGWQDS
What is the function of this protein?
Mannan endo-1,4-beta-mannosidase that exhibits high activity against konjac glucomannan and carob galactomannan, as well as a lower activity toward beta-mannan (PubMed:27193267).  Shows no activity against barley beta-glucan, birchwood xylan, and low viscosity carboxymethyl cellulose (CMC) (PubMed:27193267).  Has the ability to hydrolyze manno-oligosaccharides such as M4 which is degraded slightly to M3 and M1, M5 which is mainly degraded to M4 and M1, and M6 which is mostly hydrolyzed to M4 and M2 (PubMed:27193267).  Shows no activity toward M2 and M3 manno-oligosaccharides (PubMed:27193267).
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase, Endo-(1,4)-beta-mannanase, GH26 family endo-beta-mannanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 26 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_YERPA
Sequence: MAKNIQAIRGMNDYLPADTAIWQRIESILKQVLSGYGYSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQLGAEVFGLPGPDIDAELILLTARWWRALGIFEHVKLELNSIGSLAARADYREALVAFLEQHVEVLDEDCKRRMYSNPLRVLDSKNPDVQQLLDDAPKLSDYLDEESKQHFAGLCELLDKASIPYTVNERLVRGLDYYNRTVFEWVTHSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNADFQVPATVDAYVISSGEGAQSAAMLLAESLRDALPTLKIMTNYGGGNVKKQFTRADKWGARVALMLGESEVAAQQVVVKDLRNGEQETLAQADVAARLALMLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_CAMFF
Sequence: MDKLNRLEEHLGYKFKNKTLLKEALTHKSMKSSVNNERLEFLGDAVLDLIVGEYLFFKFKDTDEGNLSKLRAALVNEKSFASISSQIRLGDFLYLSAAEDNNNGRNKPSLVSDALEALMGAIYLESGLEAVKKIFINLLESQYNNIDLQSLGKDYKTTLQEITQARFGVTPRYELVSSSGPDHKKSFEMAVFLNDKELARAIGNSKKEAEQSAAWKVLQGMNI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_BAUCH
Sequence: MTCLTRPLPNVVAILPAAGKGRRMQTTFPKQYLTIGNKTLLELTIYTLLRQPCISQIIVAISPDDYWFAQLPIAAEERVMVVTGGSKRVYSVMRALRYVKHVSWVLVHDAVRPCLHQEDLICLLTITAHSTVGGILATPVRDTIKRAGNIANVKTINYTVVRKDLWHALTPQLFMLELLKSCLQRALKEGVTVTDESAALEYCGYQPLLVPGRADNIKVTWPEDLQLASFYLSQLTNTHNK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MSX1_LEMCA
Sequence: MTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAATAATMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAASEGAQAAGGSAQPLGVRPGSLCAPDAPSSPRPLGHFSVGGLLKLPEDGLIKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EIF3G_HUMAN
Sequence: MPTGDFDSKPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKIDEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPPSLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN
What is the function of this protein?
(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Colocalizes with AIFM1 in the nucleus and perinuclear region.