PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_LACAC
Sequence: MRMTKRVLIAGFTGAMGQKAVNLVNSLSDFKIVAGLSPSAENDPQKYNLPEDAQIFNSLDEIPDNLTDIWIDFTLPKAVYNNVKFALTHHISPIVGTTGLSDGQEAELIEISKEEKVGGIIAPNFGISAVLLMKFAKEAAKYFPDVEIIEMHHADKKDAPSGTALATAKMIAENRPAHQTAPDEVETLENVRGGDYEGIKIHSVRLPGYVAHEQVLFGGTGEALTIRQDSFDRQSFMSGVKVALEKVDQLNELVVGLENIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_METPP
Sequence: MGIEGVLKEGFITTSADKLINWSKTGSLWPMTFGLACCAVEMMHAGAARYDIDRFGMLFRPSPRQSDLMIVAGTLCNKMAPALRRVYDQMAEPRWVLSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGILQLQAKIRRENTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NARK2_THETH
Sequence: MLKSAKGTWITDWNPEDPKRWDPALAWRTLWITTFNLTLSFITWYVVSALVVRLPKVGFELSTTQLFWLTAMPGLAGGTLRIIWTFLPPILGTRHLVTFSTLLLLIPLLGWGFAVQNTGTPYWVLLLLAFLAGIGGGHFSGYMPSTSYFFPKRLQGTALGLQAGIGNFGVSIVQFVTPWIIGFALFGSLLGGPQTFTPKPGVSQPIWLQNATFAWVPFVLLGALLAWVYLRSVPIRANFREQFDIFRDKHTWIMTSLYIMTFGSFSGFSAIFPLLIREVYGKFEGAPDPLRYAFLGPLVGSLARVIAGPISDRLGGAIVTQVSAIGIFLSALLVTLYTRPTSLDQFPMFVVAMLLIFFFSGVGNASTFKQMPMIFPPRQAGGVIGWTAAVAAYGPFLFSTLAAYTQQATGGFTAFFYGLMVFYAFNFFLNWYYYARKGAEKPC
What is the function of this protein?
Probable nitrate/nitrite antiporter that may be involved in nitrate import and nitrite export during anaerobic growth.
What are the official names of this protein?
Probable nitrate/nitrite antiporter NarK2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREF2_BRUC2
Sequence: MTMRTATITEFSSSYRSLPGLLHLLQFGDSALPIGGFSFSNGLESAIQQNLVHDKETLREFTLTAMNQAATSDGIALLTAHRAARADDRGALQVIDKAVFERKLNEETRLMTVRMGRKLCELSASIIDDRLNRDWLECIKTAETPGTHPVSLGLAFAALDVDGRDAFGAQQYGVATTILGAALRLMRVSFMDTQKILLEATSTVAPAYEEIADAGIEDMASFAPMVDILAAVHVKGHVRMFMN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF 2.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_CAUSK
Sequence: MDDTLAKLPRAFSGATVLVLGDVMLDRFVYGAVDRISPEAPVPVIAVERETTMLGGAGNVARNVAALGGRAVLVGVIGDDDAGRALTAMIDREPSLDSALIVDAKRRTTEKTRYISGSHQMLRADREDRGEADGVALLAAFNAHLREVDVVVLSDYAKGVLTPVVLRAAIAAANAAGKPVIVDPKSRDFSRYDGATLIKPNRREAAEATGVTGAGDEVAAEAADAILSTAPNLAAALITRGRAGMTLAVRGEAPVHLPATALEVFDVSGAGDTVAATLALALARGASPLDAARLANLAAGLVVAKLGTDVVTADELVGLAHGEHADPAVDKIADLDGALAIVAGWRARGLKVGFTNGCFDLLHPGHVSLLAQAKAACDRLIVGLNTDASVQRLKGPTRPVQKETGRATVLASLSAVDLVVLFDEQTPLNLIRAFRPDVLVKGADYTVETVVGSDVVLAYGGKVVLAQLKAGQSTTNLIGRMNAPAVGG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: MTLD_SODGM
Sequence: MKVLHFGAGNIGRGFIGKLLADAGVEVVFADVNQQVLDALNQRHQYQVRVVGEQAQVETVRGVSAVHSGSDDVVALIASVDLVTAAVGPQILERIAPAIARGLVKRHDGGGTQPLNIIACENMVRGTSQLKQHVLNALEPRYHAWVDQHVGFVDSAVDRIVPPVEAGSDDPLAVTVESFSEWILDKTQFKGVPPALGGMELTDNLMAFMERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLINRYGFDARKHAAYINKILQRFENPYLHDDVERVGRQPLRKLGAGDRLIKPLRGTLEYGLGDANLVTGIAAAMHYHSDQDPQAKEWAALLAEVGPQAALAKVSGLEEDSEVVAQVVNAYNAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RAD2A_ARATH
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFSDDSYVESYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTDEESFNNVKQWLSEIDRYASDNVNKLLVGNKSDLTENRAIPYETAKAFADEIGIPFMETSAKDATNVEQAFMAMSASIKERMASQPAGNNARPPTVQIRGQPVAQKNGCCST
What is the function of this protein?
Protein transport.  Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
What are the official names of this protein?
Ras-related protein RABD2a, AtRABD2a, Ras-related protein Ara-5, Ras-related protein Rab1B, AtRab1B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane. Golgi apparatus membrane; Lipid-anchor.
Protein: CYSI_PSET1
Sequence: MSEQDKNVKLSDNERMKRESNFLRGTIATDLKDEITGGFTADNFQLIRFHGMYQQDDRDIRGERAKQKLEPLHNVMLRARMPGGIIKPEQWLAIDKFAEEKTSYGSIRLTTRQTFQFHGVLKPNIKGMHQLLDSVGIDSIATAGDVNRNVLCTTNPVESELHQEAYEWAAKISEHLLPKTKAYAEIWLNGEKAETTEEPILGSNYLPRKFKTTVTIPPNNEVDVHANDLNFVAIAENGKLIGFNVLVGGGLAMTHGDTATYPRKADDFGFIPLEHTLKIAEHVVSVQRDWGNRSNRKNAKTKYTLDRVGVDVFKAEVEKRAGVEFASSRPYKFTHRGDRIGWVEGIDGKHHLTLFIQSGRILDYPDKPLKTGCRKIAEVHQGDMRMTANQNLIIAGVAANQKAVIEEIARNHGLIDDKDTEQRKNSMACVALPTCPLAMAEAERYLPSLVEKIEALLAKHGVPNDSIIMRVVGCPNGCGRAMLAEAGLVGKGPGKYNVYLGGNLEGTRIPKLYLENVGEDVYLAAFDELIGQWVNERNDGECFGDFVIRKGIVAEVKVSVTDFHA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RNPH_EDWI9
Sequence: MRPEGRAAGQIRPLRLTRHYTKHAEGSVLVEFGDTKVLCTASVDEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMAREAAKGKQGGRTMEIQRLIARSLRAAVDLKKLGEFTITLDCDVIQADGGTRTASITGACVALADALGALVAAGKLKESPLKGMVAAVSVGIVAGGAVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLLALARDGIGQIIQAQKTALEQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: E111_ADEM1
Sequence: MNSRMRRWAATSRLLHEDPPATPPSQDQQAEVLRRDIHILNAKISELENQMERLCRSLESTFNRIELLHSMLAQGEEEEEEEDGAEDIEENGEESD
What are the official names of this protein?
Early E1A 11 kDa protein.
Protein: PNP_ACIBS
Sequence: MSMFNIVRKEFQFGQHQVVLETGRVARQANTVLITMGGVTVLVAVVAAPTAKAGQDFFPLTVNYQEKQYAAGRIPGGYGKREGRASEAETLTSRLIDRPIRPLFPEGYYNEIQVTATVVSSDKTMEADIAAMLGTSAALAIAGTPFRGPIGAARVGLINGEYVLNPNFEQMAQSDLDLVVAGTESAVLMVESEAKELSEDQMLGAVLFGHDEMQIAIQAINEFAAAAGAKPSDWVAPAHNEELRAKLKEAFEAKISEAYTIAVKQDRYAALDALHAEAVAQFVPEEDVDGIADEVDYLFEDLKYRTVRDNILSGKPRIDGRDTKTVRALDVQVGVLERAHGSALFTRGETQALVTTTLGNTRDALMVDTLAGTKTDNFMLHYNFPAYSVGETGRESGPKRREIGHGRLARRGVQAVLPAADRFPYVIRIVSDITESNGSSSMASVCGASLSLMDAGVPLKAPVAGIAMGLVKEGERFAVLSDILGDEDHLGDMDFKVAGSANGITALQMDIKIEGITEEIMEVALNQAFAGRMHILNEMNKVISRARPEISMHAPTFEVITINPDKIRDVIGKGGATIRQITEETKAAIDIEDNGTVRVFGETKAAAKAAIAKIQAITAEVEPGKIYDGKVIRIVEFGAFVNIMPGTDGLLHISQISNERITNVTDVLKEGQEVKVQVQDVDNRGRIKLTMKDIEQA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD1_BOVIN
Sequence: MSASVLSVISRFLEEYLSATPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DCUP_CHLTA
Sequence: MPMTGFYETISPRDQQRPPIWFLRQVGRYIPQYQELKRNRSLKDFFLDTESIVEATLLGPSLLGVDAAIVFADILSILEGFSVDYRFAPGPEVSYSPHEPLIFTKDPQETFSFLLEAIQQLTKRLTVPLIAFAASPFTLASYLIEGGASRDYPKTIAFLYQYPDRFKALLDEITLGTATYLQMQVQAGAAAIQLFESSSLRLPPHLFAKYVVAPNTKLIRQIKQTGNPPISLFCRCFYQEFLSLYAIGADTLHPDYHVELPEVYRQIHSPGSIQGNFDPALLLLPQDALIAHLEAYLAPLKQQSHYIFNLGHGILPQTPIENVQAVVSCLTSISTS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA3_MOUSE
Sequence: MAAAAELRLLEKSLGLKPGNKYSAQGERQIPVLQTNNGPSLMGLSTIATHLVKQASKEHLLGSTAEEKAMVQQWLEFRVTRVDGHSSKEDTQTLLKDLNSYLEDKVYLAGHNITLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPDIRQHLSSIVFIKNRLYANSH
What is the function of this protein?
Positive modulator of ATM response to DNA damage.
What are the official names of this protein?
Eukaryotic translation elongation factor 1 epsilon-1, Elongation factor p18, Multisynthase complex auxiliary component p18.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes at S phase and following DNA damage.
Protein: RS10_PSYIN
Sequence: MQNQRIRIRLKAFDHKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILVSPHVNKDARDQYEIRTHKRLIDIVEPTEKTVDALMKLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: OTCC_STRP1
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QTRT2_TRIAD
Sequence: MNFKVRVIDLAGSCCRLGALQFGTKVVETPGCLIYNRSGVVPHLTPDILETLDNVPPIMHTPLASIIEEPGLIKLRGYGKGLASFIGYKDNSVYISASDYQGEAMYQYNENKSISVWTKTGRTKVTPDDYSKFVEVCRPSWYQSLCDTVPANASIKRTRKSVDRTLEFLDQCLKYREKHDSLKTSELWAAVEGGGLVDERQRSAKESATRPVFGFTLEGFGSDQMNVETIFELLPLTTQNLPVEKPRLIHAIGSPTINSLSRSSKLTEVEEENGNDSSNDQDRTATFSLLNLREDRYNEDFSPLVSGCKCFVCSNHTRAYIHHLIINNEMLGGVLLMTHNLFQYIEFFRCIRTSLKNNKWKELRKLFDA
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_NITOC
Sequence: MENSAPLVAIVAGEASGDQHAAHLIREVKKIAPGVRFGGIAGPQMRAAGVEPLFDSSRLAVVGLVEVLSHLNEIYGAMQKMRHFLEEKHPDLLILVDYPEFNLRLAKRAKTLGIKVLYYISPQVWAWRQYRVHQIGQVVDMMAVVLPFEVPFYEQAGVPVNFVGHPLQHEVKSKFNRNEAVVEFGFNPCCKTLGLLPGSRHSEIKRLLPVLLEAAERIYSEEPEIQYLLPLAATLKEIDLAPYLKGYRLPLRVIPDRSYDVMAACDAMVAASGTVTLEAALMGVPLVVIYKMNSLSYWMGRLLIKVDHIALCNIIAGEGVAPELIQQDASPERIALEALNLLRDKERRQTMQQKFYAIKHKLGAGAQRTIAELTVAMLEGENLGRAS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: PLSB_AERHH
Sequence: MSLGQNISRAILQWPVSGLVNHKSLPENPITELKLDPARPIVYALKTSSITDLMTLQQCCEDLGLPGPFTPLELNGQLLPRYVCLDRPPPLFGKRSKPLPFLQEFHQLLDLHKQDPALDIQVVPVTLFWGRAPGREGEEASGWNIISSLAPNRLKKALIVILKGRENLVRFSPPLSLRHMADKHGTDEAIAHKLARVARTHFSRQQLAATGPKLPNRNLLFKQLLDSNVIQQAIEEEAQREGISLEKAQKRAHGYMDEIASDFSYRLIRLGESFLGWLWNKLYRGLSVNGAEKVRQLAQEGHEIVYVPCHRSHMDYLLLSYVIYHQGMVPPHIAAGINLNFWPAGPIFRHGGAFFIRRTFKGNPLYSTVFREYLNLLFAKGYSVEFFTEGGRSRTGRLLPPKTGMLAMTLQAMMRGLDRPVTLVPVYLGYEHVMEVNTYHNELKGSRKEKESFLQVLGILRKLRNYGRGFVNFGEPLTLNNYLNEHVPSWKEHIGEEERPEWMAPTVNQLAELLMTRINGAAAVNGLTLSALALLAAERHALTRDELQAQLNTYLDLLKQVPYSPHSTIPDEDAKTLLDQAMELNKFEVSEDKLGQIVSLDRYQAILLTYYRNNILHLFAMPSLVAALIERCEGISRSEIVARCIDIYPLLKTELFLRYEEDELPELVDALLAELQRQQLIEARDGGFWVNPVNQTRLLLLAESIQETLQRYAIVLTRVLAQPRIEAEQLEADGLMMAERLGTLHGINAPEFFDQKLFSTLIHTLRSEGYLDPGCKPDLGRFQALADNIVPLLSTKIRRTIQAGNRL
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNPH_CALS8
Sequence: MRQDQRSYNELRPIKITRNFIKYAEGSCLIEMGNTKVIITATIDDKVPPFKKGSGEGWITAEYSMLPRATQQRNVRDINKLRLSGRSHEIQRLIGRALRAGINFKALGERVIILDCDVIQADGGTRTASITGGFIAMFDACKKLYDDKVIENFPITDFVAAVSVGICDGVEMLDLCFEEDSKASVDMNLVMNDKGEFIEIQGTAEGGAFTQEQFEKLLELGKQGIQKIIEIQREVLGEDSKLIGSVPKDEKTSGCDQE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MMAD_RAT
Sequence: MAHVLCNRARLVSYLPGFCSLVKRVINPRAFSTAGSSGSDESHVATAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSQAHKTLPDVLAEPLSTERHEFVMAQYVNEFQDSNAPVEQEISSAETYFESARVECAIQTCPELLRRDFESLFPEVANSKLMILTVTQKTEHDMTVWSEEVEVEREALLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHGLWGTHVVVGSIFTNATADSHIMRKLSGD
What is the function of this protein?
Involved in cobalamin metabolism and trafficking.  Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl).  Promotes oxidation of cob(II)alamin bound to MMACHC.  The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
What are the official names of this protein?
Cobalamin trafficking protein CblD, CblD, Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: UBIG_BORA1
Sequence: MTTANSASRPNINVDQAELDKFSALAARWWDPESEFKPLHAINPLRLEWIQELAGSLQGRRVLDVGCGGGILSEAMAQAGADVTGIDLAEKSLKIARLHGLESGVKVEYRAVPVEELATEQAGQYDIVTCMEMLEHVPDPNSVVRACAALVKPGGWVFFSTLNRNPKSFLFAIIGAEYVLRLLPRGTHSYEHFIKPSELAASARQAGLEPSGMRGMEYNPITQIYSLSGNTSVNYLMATRK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: GMSS_CLOTT
Sequence: MEKKTIVLGVIGSDCHAVGNKILDHSFTNAGFNVVNIGVLSSQEDFINAAIETKADLICVSSLYGQGEIDCKGLREKCDEAGLKGIKLFVGGNIVVGKQNWPDVEQRFKAMGFDRVYPPGTSPETTIADMKEVLGVE
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: ISPE_CHLPD
Sequence: MDHLSVKSFAKINLGLLITGKRKDGYHTLETIFAPINWYDTIGFSDSDVISMSCSNIDLPVDDNNLCIRAARALQQSASCSKGAAMNLQKVVPFGAGLGGGSSDAATVLRVLNELWKINVSSAELHELAVKLGADVPYFLEMKGLAFARGIGDELEDLGLTLPFHVVTVFPEEHISTVWAYKNFYQKFDRPVPDLRLLLQRLCLDGDRSVLGAFENDFEPAVFDHYPKVRVVKESLLDAGSFYASLSGSGSAVFGLFDTLENAAGAVCAMQQKGYRVTLTPPGFSMEAQAGSRL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RS6_METC4
Sequence: MPLYEHVFLARQDVTAQQVETMVETYKGVIETGGGTIEKIESWGVKSLAYRIKKNRKAHFTLLNISAPPAAVAEMERQMQISEDVLRFMTVRVEQLEAEPSAMMQKRDRDDRKDRDRGDRPRRRDDDFGGGDRGDRGDRGDRPERNFGGEN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GCH4_COLP3
Sequence: MTTSMPDIANHTTAQTEGTLDWVGMSNIEMPIMVASKGESERMVSAHIDAFVNLKDAQAKGIHMSRLYLLIDELSTSNILNYQSLVSLLDGFISSHQELSDQAKVQFCFDYHLRRKSLISGKEGWKAYPVTLTGNLNQGKLTIELTIDVPYSSTCPCSAALARQLIQKAFQDKFAQQSELALTDVHDWLGTTEGIVATPHSQRSVAEVKVKLNSSINDFPITEIVDLVENSLKTPVQAAVKREDEQEFARLNGQNLMFCEDAARRLQHSLNQTDQFDDFWLRINHLESLHAHDAVSVTTKGIKDGYQP
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: FLIT_HALH5
Sequence: MSSLEQLSQLTNDLYAKVHAPLDSNHDLREKQMENIEQLLKERALVMEMGLERPKDQKSKQIVREILMKSQAIQEKLAEMSGMIHQEINQFKQKKQMNRKYDLPYDGPTVEGVFFDKRE
What is the function of this protein?
May act as an export chaperone for the filament capping protein FliD.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the bacillales FliT family.
Protein: HELI_HCMVM
Sequence: MSMTASSSTPRPTPKYDDALILNLSSAAKIERIVDKVKSLSRERFAPEDFSFQWFRSISRVERTTDNNPSAATTAAATATVHSSVSSSAAAAASSEAGGTRVPCVDRWPFFPFRALLVTGTAGAGKTSSIQVLAANLDCVITGTTVIAAQNLSAILNRTRSAQVKTIYRVFGFVSKHVPLADSAVSHETLERYRVCEPHEETTIQRLQINDLLAYWPVIADIVDKCLNMWERKAASASAAAAAAACEDLSELCESNIIVIDECGLMLRYMLQVVVFFYYFYNALGDTRLYRERRVPCIICVGSPTQTEALESRYDHYTQNKSVRKGVDVLSALIQNEVLINYCDIADNWVMFIHNKRCTDLDFGDLLKYMEFGIPLKEEHVAYVDRFVRPPSSIRNPSYAAEMTRLFLSHVEVQAYFKRLHEQIRLSERHRLFDLPVYCVVNNRAYQELCELADPLGDSPQPVELWFRQNLARIINYSQFVDHNLSSEITKEALRPAADVVATNNPSVQAHGGGGSVIGSTGGNDETAFFQDDDTTTAPDSRETLLTLRITYIKGSSVGVNSKVRACVIGYQGTVERFVDILQKDTFIERTPCEQAAYAYSLVSGLLFSAMYYFYVSPYTTEEMLRELARVELPDVSSLCAAAAATAAAPAWSGGENPINNHVDADSSQGGQSVPVSQRMEHGQEETHDIPCLSNHHDDSDAITDAELMDHTSLYADPFFLKYVKPPSLALLSFEETVHMYTTFRDIFLKRYQLMQRLTGGRFATLPLVTYNRRNVVFKANCQISSQTGSFVGMLSHVSPAQTYTLEGYTSDNVLSLPSDRHRIHPEVVQRGLSRLVLRDALGFLFVLDVNVSRFVESAQGKSLHVCTTVDYGLTSRTAMTIAKSQGLSLEKVAVDFGDHPKNLKMSHIYVAMSRVTDPEHLMMNVNPLRLPYEKNTAITPYICRALKDKRTTLIF
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs.  Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
What are the official names of this protein?
DNA replication helicase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae helicase family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RUTA_KLEP3
Sequence: MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSKIQIYATAATLTLPPAIVARMASTIDSISGGRFGVNLVTGWQKPEYDQMGMWPGDDYFASRYDYLTEYVQVLRDLWGTGRSDFKGDYFTMNDCRVSPRPSQPMKVICAGQSDAGMAFSAQHADYNFCFGKGVNTPTAFAPTAARMIQAAEKTGRDVGSYVLFMVIADETDEAARAKWEHYKAGADEEALAWLTEQSQKDTRSGSDTNVRQMADPTSAVNINMGTLVGSYASIARMLDEVASVPGTDGVLLTFDDFLAGIDAFGERIQPLMRCRDHIAPVTREVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.