PharMolix/UniProtQA huggingface dataset:
Protein: RPB2_CANGA
Sequence: MSADNEDYYDEDPYGFEEENAPITAEDTWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIISEDSTLILEQLAQHTTEQDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVTKRTYEAVDVPGRDLNYQLIAEESEEDSESGKVFIGRLPIMLRSKNCYLSDATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGRESSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFRKLTKDIFRYMQRTVEEANDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGADPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREQELKIFTDAGRVYRPLFIVEDDEELGRKELKVRKGHVAKLMATEYQDIEGGFEDAEDYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPTAVEQDIPKENVDLAKRIKVTHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNFRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDEDGLIAPGVRVSGEDIIIGKTTPIAPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLITTNQDGLKFVKVRVRTTKVPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAAFLKERLMEASDAFRVHICGICGLMSVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BREF3_EUPBR
Sequence: MFDIYDYSPRLVALGLIAATIIIYSFTLTVYRLFFHPLARIPGPKLCAITGWYEIFWDVLVGGQFTFKIEEWHKTYGPVMRIGPNEVHFNDPDFYNELYPTIGATYEKPAQWRWRFGCGTAIFDTIGHEHHAQRKAPVAAFFSRQKILQFSGFIQDQTDILVKRIRDDHRGQVICANEAFDALTMDIIGYYAFGLSYNSLQYPGFKAPYRNVTADIARMVHVGAHFPWVFTILNALPEKYITRLLPPMSKIFMFRKEISSQIRRIKDNKEYLDKNVNEHRTVFHEILNSNQPACELNEGRIYHEALSLVGAALETSKRTTALAVYYILATPGVEDNLRAELTAAMPDKTKNLSVPELEALPYLNAVIKEALRLAIGVSQRMRRYSPTETITYKDYTIPPNTVFGMCHWEQLRDARIWDRPTEFLPERWLAEQPLALNGQPLNKYFVPFHRGPRMCLGKEFGMAQLNIGLATLFRQDDIKLELYETDRKDVDVVADFFVPLTVKESQGVRVLVK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of brefeldin A (BFA), a protein transport inhibitor that shows antiviral, antifungal, and antitumor properties (PubMed:24845309).  The proposed biosynthesis of BFA involves formation of an acyclic polyketide chain that is differentially tailored throughout the backbone (PubMed:24845309).  The highly reducing polyketide synthase Bref-PKS is proposed to synthesize the precisely reduced octaketide precursor, which could then be directly offloaded by the thiohydrolase enzyme Bref-TH followed by a cytochrome P450 monooxygenase-mediated formation of the cyclopentane ring and macrocyclization to afford 7-deoxy BFA.  Alternatively, the first ring annulation can also occur on the ACP-tethered intermediate before the thiohydrolase release and lactonization (PubMed:24845309).  The C7-hydroxylation by another cytochrome P450 monooxygenase is believed to be the final step in the process to obtain the final structure of BFA (PubMed:24845309).  In addition to the HRPKS Bref-PKS and the thiohydrolase Bref-TH, the brefeldin A biosynthesis cluster contains 4 cytochrome p450 monooxygenases (called orf3 to orf6), as well a the probable cluster-specific transcription regulator orf8 (PubMed:24845309).
What are the official names of this protein?
Cytochrome P450 monooxygenase orf3, Brefeldin A biosynthesis cluster protein orf3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MPRB_MYCTO
Sequence: MWWFRRRDRAPLRATSSLSLRWRVMLLAMSMVAMVVVLMSFAVYAVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYSDVNAMLVNPGQSIYTAQQPGQTLPVGAAEKAVIRGELFMSRRTTADQRVLAIRLTNGSSLLISKSLKPTEAVMNKLRWVLLIVGGIGVAVAAVAGGMVTRAGLRPVGRLTEAAERVARTDDLRPIPVFGSDELARLTEAFNLMLRALAESRERQARLVTDAGHELRTPLTSLRTNVELLMASMAPGAPRLPKQEMVDLRADVLAQIEELSTLVGDLVDLSRGDAGEVVHEPVDMADVVDRSLERVRRRRNDILFDVEVIGWQVYGDTAGLSRMALNLMDNAAKWSPPGGHVGVRLSQLDASHAELVVSDRGPGIPVQERRLVFERFYRSASARALPGSGLGLAIVKQVVLNHGGLLRIEDTDPGGQPPGTSIYVLLPGRRMPIPQLPGATAGARSTDIENSRGSANVISVESQSTRAT
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA.  MprB/MprA is involved in regulation of numerous stress-responsive genes (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_CEPHR
Sequence: MTNIRKTHPLLKIENNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTYMETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGISSDTDKIPFHPYYTIKDILGALLLVLALMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLMPLLHTSKQRSMMFRPISQCLFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NANE_VIBC3
Sequence: MRPVVRKNFLNIEELKRFLNGQTVVSIQPVTGSPLDKTDFIVAMAIAVEQAGAKALRIEGVNNVAAVSAAVTIPIIGIVKRDLPDSPIRITPFVSDVDGLANAGATVIAFDATDRTRPESRERIAQAIKNTGCFAMADCSTFEDGLWANSQGVEIVGSTLSGYVGDIEPTVPDFQLVKAFSEAGFFTMAEGRYNTPELAAKAIESGAVAVTVGSALTRLEVVTQWFNNATQVAGERKCAH
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: CMOB_ECOK1
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: F16PA_CHLP8
Sequence: MNKLTTIESHFLQQQKLYPEINSEVTGLLNDVAFAAKLVRREVVRAGLADILGLAGSTNVQGEEVKKLDLFANERLINAIGQHGRFAIMGSEENEETITPPKFESGEYVLLFDPLDGSSNIDVNVSVGTIFSIYRLKSDNPSQASIEDCLQKGADQVAAGYVIYGSSVMLVYTTGHGVHGFTFDQTVGEFLLSHENITTPEHGKYYSVNEGSWNEFHDGTKLFLDYLKEEDKATGRPYSTRYIGSFVADFHRNLLTGGVFIYPATKKHKNGKLRLMYEANPMAFICEQAGGRATDGHRRILDIEPVELHQRTPLYIGSKNDVLIAEEFEQDKR
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_MYCLE
Sequence: MSTNQGSLWGGRFAAGPSEALVALSKSTHFDWVLAPYDITASRAHTKMLFRAGLLNEEQRDGLLAGLDNLAEDVADGSFLPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVAAGALEVVDALANQAAEHSSTIMPGKTHLQSAQPILLAHHLLAHAHPLLRDVGRIVDFDKRAAVSPYGSGALAGSSLGLDPDAMAQDLGFPAAADNSVDATAARDFAAEAAFVFAMIAVDLSRLAEDIILWSSTEFGYARLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVERMAALAPAGYTLATDIAEWLVRQGVPFRSAHEAAGTAVRVAEGRGVGLEELTDDELAAISANLTPQVREVLTVEGSVSSRAARGGTAPSQAAKQLTVVRANANQLRQLLMR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1873_AQUAE
Sequence: MKILIVSFDKTLVDSLKEHLAQHEVYTAKNAEEAITLSPSDIDLIIFDAISGAISEEEINELYSKKFKNQKYVILYDELFPVDPKNILPPNKVLVLRDSPPEEIIRRALEEKKEETKEEGIEIGASVPVEEELKTEKKEEKVEKEETGKAKVLVVSFDKKLTDNITNALKGKFSVEVVRNIKSVKEKGLEADIIVYDAISGSIAEKNLMELAEVPQLREKHFIILVDELFPIDVEKINLPNKSTLNRDAGAEAIAEEVEKVAQKVKKEEIKSMETEEVKEEKVREEIPEEVPQEVEEIKEEKPEMSEIKEKTEAISTKEKTPEAVQVLAEKLSDEKFIRSLLVEAISKELHGVREEIKAEVRDYIKNVLESIIREEIERAFAEVGVAKIIREETKRIVEEKIKELLK
What are the official names of this protein?
Uncharacterized protein aq_1873.
Protein: FRDD_VIBVU
Sequence: MKPNYNVDRAPKRSDEPVWWSLFGAGGTWFAMITPVTVLVLGILVPMGVINAEALSYDRVVSFATSIIGALFIIATLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAVAGLISALAVVFIFML
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_PSE14
Sequence: MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKNDDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRNILFICGGAFSGLEKVIQNRSTRGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDEAALIQILTEPKNALTKQYAKLFEMEGVDLEFRTDALKSVARRALERKTGARGLRSILEGVLLDTMYEIPSQSDVSKVVIDESVIDGTSKPLLIYENSEPPAKVAPDA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PSBJ_LOTJA
Sequence: MADTTGRIPLWIIGTVTGITVIGLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SKA2_BOVIN
Sequence: MEAEVDKLELMFQKADSDLDYIQYRLEYEIKTNYPDSAGKKNPVTLLKELSAIKSRYQTLHVRFKPIAVEQKETKSRICATFNKTMTLIQELQKETDMELLPLTEEEKTAAEQLRAHMSDL
What is the function of this protein?
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint.  The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies.  The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner.  In the complex, it is required for SKA1 localization.  Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Spindle and kinetochore-associated protein 2, Protein FAM33A.
What is the protein family that this protein belongs to?
Belongs to the SKA2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore- associated proteins.
Protein: RRF_STRZP
Sequence: MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGNTPANDGSVIRLVVPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTN4_HUMAN
Sequence: MASLLQSDRVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSHEVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTTMKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHTQRMNKLIEYYQQLAQKEKVERDRKKLARRRNYMPLAFSDKYGLGTRLQRPRAGASISTLAGLSLKEGEDQKEIKIEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDFQPVCASQLYPRHKHLLIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLLTLTNPVENLTHVTLFECEEGDPDDINSTAKVVVPPKELVLAGKDAAAEYDELAEPQDFQDDPDIIAFRKANKVGIFIKVTPQREEGEVTVCFKMKHDFKNLAAPIRPIEESDQGTEVIWLTQHVELSLGPLLP
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 4, Dyn4, Dynactin subunit p62.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunit 4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere. Note=Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin (PubMed:10671518). Overexpression in cultured mammalian cells revealed colocalization with cortical actin, stress fibers, and focal adhesion sites, sites of potential interaction between microtubules and the cell cortex (By similarity). In skeletal muscles, costamere localization requires the presence of ANK2 (By similarity).
Protein: BUD32_ENCCU
Sequence: MGFHFQGAESIISADGETVVKKRARKAYRIEALDLKIINGRTKREAKILRKLEALGIPAPRLISTYGDTIVMEKVEGTVLKEMIDSSDNPGALFRDLGALVSRLHIADIIHGDLTTSNFIHGSKIYAIDFGLSYISRKDEDKAVDLYVFEKAVGCAHDAKFLEDFYCGYMGEGSESVLKKLGTVRLRGRKREAMAFG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: MDTA_SHIFL
Sequence: MLDNLIGARYLTGLGTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLMVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
What are the official names of this protein?
Putative multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPS_SALPB
Sequence: MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_PECCP
Sequence: MSEVTSFAVFGNPIAHSKSPRIHELFAAQTGITLTYERVLAPLDDFEQVLRQYFLNCAGGANVTAPFKERAFAESDERSECAALAGAVNTLKRLSDGRLFGDNTDGIGLLSDLQRLALVKPLDRVLLVGAGGAARGVIQPLLAYGCTVVLTNRTFSKADELVKVFSGIGDIHAVSLDDLHGLSFDLIINATSSGMYDSIPNLPPELISPETGCYDMFYLPQLTPFLSWCVQHGAIRYADGLGMLVGQAAHAFKLWHGVMPDVEPVIALLKQDLAT
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: Y4WO_SINFN
Sequence: MAVPSCQTDGVRALKFVDHVGGEELGDNVRGVVLIACTTISMSPWPVTGMAGLVGSRTVSTSGVRICGLTATGTVIAHQLHMTVAAVGFRRIGLAGDRARPIWRIS
What are the official names of this protein?
Uncharacterized protein y4wO.
Protein: HDFR_YERE8
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLLPYAETLMSTWQLAKKEVAHSLQHTELSIGATASLWEAYLTPWLQQLYKQRETLRLEARIALRQSLVKQLHERQLDLLITTEPPKMDELASLLLGHFSLRLFSSIPFELPEKTDDGTEHKNANEAPYIKLEWGADFHQQESRLLNSEQMPVLTTTSAHLTRQLLDTTGGCAFLPEHWQKEYPELVVNADIPPIVRPLYAVWLQNSDQQTLIRQLLKTPMNNAAQSAIRD
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: H2B2_CANAL
Sequence: MAPKAEKKPASKAPAEKKPAAKKTASTDGAKKRTKARKETYSSYIYKVLKQTHPDTGISQKAMSIMNSFVNDIFERIASEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSASN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RR12_PINTH
Sequence: MPTIQQLIRNARQPIENRKKSPALRGCPQRRGVCARVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIDHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAAEVKDRQQGRSKYGVKKQK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS19_SHISS
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: OMPA_SALTY
Sequence: MKKTAIAIAVALAGFATVAQAAPKDNTWYAGAKLGWSQYHDTGFIHNDGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVPGGPSTKDHDTGVSPVFAGGIEYAITPEIATRLEYQWTNNIGDANTIGTRPDNGLLSVGVSYRFGQQEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKSTLKPEGQQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSDKISARGMGESNPVTGNTCDNVKPRAALIDCLAPDRRVEIEVKGVKDVVTQPQA
What is the function of this protein?
Required for conjugation with F-type plasmids; probably serves as the mating receptor on recipient cells.
What are the official names of this protein?
Outer membrane protein A, Outer membrane major heat-modifiable protein, Outer membrane porin A, Outer membrane protein 33K.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y556_STAEQ
Sequence: MKFLSFKHNDRTSYGVKVKREDAVWDLPMVFAEFGDKDFNPKTLIAGLQQNQTLDFQEQVRKAVVAAEESGRDEEFKLLFTDIDFLPPVTPPNNVIAFGRNYEDHASELNHEVDSLYVFTKAASSLTGDEATIPNHKDITEQLDYEGELGIVIGKSGEKIPRGLALDYIYGYTIINDITDRTAQSSHDQAFLSKSLTGACPMGPYIVTKDELPAPENVNIVTKVNNEIRQDGNTGEMILKIDELIEKISKYVALHPGDIIATGTPAGVGAGLQPPQFLQPGDEVKVTIDNIGTLTTYISKN
What are the official names of this protein?
Uncharacterized protein SERP0556.
What is the protein family that this protein belongs to?
Belongs to the FAH family.