PharMolix/UniProtQA huggingface dataset:
Protein: EXD_DROME
Sequence: MEDPNRMLAHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEFTTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNIGKAQEEANLYAAKKAAGASPYSMAGPPSGTTTPMMSPAPPQDSMGYPMGSGGYDQQQPYDNSMGGYDPNLHQDLSP
What is the function of this protein?
Transcription factor which acts with the selector homeodomain proteins altering the regulation of downstream target genes such as wingless (wg), teashirt (tsh) and decapentaplegic (dpp), thus affecting segmental identity.  Delimits the eye field and prevent inappropriate eye development.  Required for proper localization of chordotonal organs within the peripheral nervous system.
What are the official names of this protein?
Homeobox protein extradenticle, Dpbx.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear translocation requires interaction with hth.
Protein: TFS_ARCFU
Sequence: MEFCPKCKSLMIYQGDKLVCRKCGYEKEADDSEELVIKVERNKEDVPVIEGENLKTLPTTKAICPACGHNEAFWWLRQLRAADESEVRFFRCTKCGKTWREYD
What is the function of this protein?
Induces RNA cleavage activity in the RNA polymerase.  In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA.  The truncated RNAs are able to continue elongation.  Involved in transcriptional proofreading and fidelity.  Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end.  TFS is able to induce a cleavage resynthesis cycle in stalled elongation complexes (resulting from the next missing nucleotide or a reduced incorporation rate of a wrong nucleotide) preventing misincorporation and enabling proofreading in a post-incorporation manner.  Pausing of elongation complexes is the main determinant of TFS-induced RNA cleavage.
What are the official names of this protein?
Transcription factor S, Transcription elongation factor IIS/RNA polymerase subunit homolog, TFIIS/RPSU homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Protein: DUT_SALSV
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GLYA_NITMU
Sequence: MLSSYNTLETVDPDLWQAIKGEMQRQEEYIELIASENYASPAVMQAQGSVLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVRALFDAEYVNVQPHSGSQANAAVYLTALKPGDTLLGMSLAHGGHLTHGASVNLSGKIFNAVSYGLRSDTEELDYDEVARLAHEHKPKLIVAGASAYSLVIDWKRFRKIADDIGAYLFVDMAHYAGLVAAGYYPNPVGIADFVTSTTHKTLRGPRGGIIMARAEHEKALNSAIFPQTQGGPLMHVIAAKAVAFKEAASQEFKDYQEQVIDNARVMAKVLQERGLRIVSGRTDCHMFLVDLRPKYITGKQAAESLEVAHITVNKNAIPNDPQKPFVTSGIRIGSPAITTRGFAEFESEQLAHLIADVLEAPTDSSVLTEVARQAKALCAKFPVYQG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_PINTH
Sequence: MNRRSKWLWIEPITGSRKRSNFFWACILFLGSLGFFLVGISSYFGENLIPLLSSQQILFVPQGIVMCFYGIAGLFISSYLWCTILFNVGSGYNKFDKKKGIVCLFRWGFPGINRRIFPRFLMKDIQMIKMEIQEGISPRRVLYMEIKGRQDIPLTRTGDNVNLREIEQKAAESARFLRVSIEGF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CHI1_PEA
Sequence: EQCGNQAGGXVPPNG
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase A1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: FAU1_PYRHO
Sequence: MSTESEISVRIRGIYSTALTKLLLDKGFKIVQPSDIIAERLGLEKSYEDFDIDIYDRNHGITVVGTKVEEIRKVLEEELIDVFFRKLPYKLYGVYKGIVVKRDDRYVYVDIGNAIGTVLIEELPDATEGDEVIVQVKKHNVLPHLSVLITIPGDYAVLIPKPIGVQRHVKISRKIRDPEERERLRILGLSVNLGEWGILWRTAAAYKEWSVLRDEIVRLSKVADKLKEAEKYSAPAEIIEGRNIYEIEFGGGAKKKLDEIRNKVVPTIEGHHQYKSYDPEFTLAVEVAEGILAKMPSQRQKISEGFIEAIVNSKGPKLGWMFTLNHVKPDGQVIKIGPGEVIEVSVKPLKVKIRRNLKPGRVYDGLEVPIEPGDYAITEIEAGKWWFVHRYYDRNGNLKGEFYNINTPVEIYPDKARYIDLEVDIVKWPDGKKEIIDKEKLKEHYEDGIISEKLYKSVLRIVQEIYEKV
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: RPOZ_DICT6
Sequence: MKEIDIDTLISKIPNKYILTVVISRRARQLFEELKILKTVARDPLILAMEEVAQDKITYGEGSDSED
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: AMP_POCDA
Sequence: MKVLVILFGAMLVLMEFQKASAATLLEDFDDDDDLLDDGGDFDLEANSDASSGNGNDSNDAVPEKRRACADLRGKTFCRLFKSYCDKKGIRGRLMRDKCSYSCGCRG
What is the function of this protein?
Cationic peptide with probable antimicrobial activity against coral pathogens.  Shows in vitro activity against Gram-positive bacteria and the filamentous fungus F. oxysporum (MIC=1. 25 uM).  Gram-positive bacteria tested are B. megaterium (MIC=20 uM), S. aureus (MIC=5 uM), M.  luteus (MIC=1. 25 uM), B. stationis (MIC=10 uM), M. maritypicum (MIC=20 uM).  Has no or little effect against Gram-negative bacteria (the coral pathogen V. coralliilyticus (MIC>20 uM), V. aesturianus (MIC>20 uM), V. shiloi (MIC>20 uM), and E. coli (MIC=10 uM)).  Has no hemolytic activity against sheep erythrocytes.
What are the official names of this protein?
Antimicrobial peptide damicornin.
What is the protein family that this protein belongs to?
Belongs to the coral AMP family.
What are the subcellular locations of this protein?
Cytoplasm, Stress granule. Secreted.
Protein: Y3997_ARATH
Sequence: MLEKLSFLLHKFPLVSKCGFIKKLASESSNDSNIIRIPDFPGGAEGFELVIKFCYDISFEINTENIAMLLCAAEYLEMTEEHSVENLVETIEVYLNEVILKSLSKSVKVLQKSQDLLPIAERVRLVDRCIDSIAYAICQESQSNEDIVDWWADDLAVLKIDMFRRVLVAMIARGFKRYSLGPVLKLYAEKALRGLDIFGKEAKKMEAEQEHEKRLILETIVSLLPRERNSVSVSFLSILLRAAIYLETTVACRLDLEKRMGLQLRQAVIDDLLIPYYSFNGDNTMLDVDTVQRILMNYLEFEVEGNSADFASDIGELMETYLAEIASDRNINFAKFIGFAECIPKQSRMYRAIDIFLKTHPNISEVEKKKVCSLMDCKKLSRDVYAHAAQNDRFQENLSNSDSPAPATAEKTLSPPELSSYKNELSKLNRENQYLKLELLKVKMKFKELEKEKAFEVMSGSDCSSSVSTASVAKPRLPRKSFINSVSQKLGKLINPFGLKQGQTKQPKSRRHSIS
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Putative BTB/POZ domain-containing protein At3g49970.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: RL35_PAEAT
Sequence: MPKMKTHSGAKKRFKLTGTGKLKRQQANRRHYLEHKSSRLTRRLAGDKLVFKGDAKVIKKMLGV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: VATH_HUMAN
Sequence: MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSPEEKQEMLQTEGSQCAKTFINLMTHICKEQTVQYILTMVDDMLQENHQRVSIFFDYARCSKNTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTVSSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).  Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (PubMed:12032142).
What are the official names of this protein?
V-type proton ATPase subunit H, V-ATPase subunit H, Nef-binding protein 1, NBP1, Protein VMA13 homolog, V-ATPase 50/57 kDa subunits, Vacuolar proton pump subunit H, Vacuolar proton pump subunit SFD.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase H subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: NHAA_STRAW
Sequence: MAAPRTSTRKFLGRLSLPERNFVAEALRTETVGGVLLLLAAITALIWANVPALHHSYESVSHFHFGPAPLGLDLSVQHWAADGLLAVFFFVAGIELKRELVAGDLKDPKAAALPVAAALCGMAVPALVYTLTNLTGGGSLRGWAVPTATDIAFALAVLAVIGTSLPSALRAFLLTLAVVDDLFAILIIAVFFTADLNFAALAGAVIGLAVFWLLLRKGVRGWYVYVPLALVIWGLMYNSGIHATIAGVAMGLMLRCHRHQGEEHAPGEHIEHLVRPLSAGLAVPLFALFSAGVVISGGALGDVFTRPETLGVVLGLVVGKAIGIFGGTWLTARFTRASLSDDLAWPDVFAVASLAGIGFTVSLLIGELAFDGDPVLTDEVKAAVLTGSLLAALIATTLLKLRNAKYRALCEDEERDEDSDGIPDIYEQDNPAYHLRMAEIYERKAAEHRRLAEVTGGAGAENDGPA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSX_CALBD
Sequence: MRIGIDAMGGDNAPHAVIEGVALYLKENRDDEIVIFGDKNIIEEECVQKVQPLDKLEIIDCKEKIEFEDEPVKAIRQKKDSSIVVGLQYLKEGKIDAFVSAGSTGALMAGGLLIVGRIKGIDRPALTTRLPYKDGQYLLIDVGSNTDCRPINILQFAQMATVYVSKVLGKKNPTVGLLNIGTEENKGNDLSKQSYELLKSAKNINFVGNVEARSLPFSPPDIVVCDGFVGNIVLKLTEGMGLLFFDILKDIAKSSFRAQIGGLLLKPYLKRLKGKYDYKEVGGAPLLGIDGIIVKCHGSSDGQAIFSGIHQAKAFYENNVLALLKEEITAESEV
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: BORC8_MOUSE
Sequence: MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKADMQRWEEQSQGAIYTVEYACSAVKSLVDSSVYFRSVEGLLKQAISIRDHMNTSAQGHSQEKLSPPPSLA
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the BORCS8 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: GAG_HV1S2
Sequence: MGARASILSGGKLDDWEKIRLRPGGKKKYRIKHLVWASRELDRFALNPGLLESAKGCQQILVQLQPALQTGTQEIKSLYNTVATLYCVHQRIEIKDTMEALEKIEEIQNKNKQQAQKAETDKKDNSQVSQNYPIVQNLQGQPVHQALSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTIGGHQAAMQMLKDTINEEAAEWDRVHPVHAGPIAPGQVREPRGSDIAGTTSTLQEQIGWMTGNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKALRAEQATQDVKNWMTDTLLVQNANPDCKTILKALGSGATLEEMMTACQGVGGPGHKARVLAEAMSQVTNTNIMMQRGNFRDHKRIVKCFNCGKQGHIAKNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSSKGRPGNFLQSRPEPTAPPAESLGLGEEIPSPKQEPKDKELYPLTSLKSLFGSDPLSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: CTAA_RHOCS
Sequence: MTSLSLSPAAGPQRSAAAPKAVAVWLLVCAGMVFAMAIIGAITRLTESGLSITEWKPVTGALPPLSEAQWLAEFEKYRQIPEYQLLKRGMSLEEFKGIYFWEWLHRLWGRLIGVVFLLPFVWFWVRGQVSRALAPTLAGLFLLGGLQGFIGWFMVQSGLTERTDVSHYRLALHLGMAFLIYAALLKVALGLLDPAPAPQPAAGRLRPHAWAALALLGVTIVWGAFVAGINAGFAYNTWPLMGGTLAPAEMWTQTPVWLNLLENTAAVQFVHRWLAVVTALVVLSLCWQAWRTGGGTRLRGVAAGLAAATVAQVGLGIATLLSVVWIPLATAHQGGALVLTGLLVWTLHLLRPPETPRQATPLTATPLTEMPAPR
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHAP2_SHEB5
Sequence: MDANSINSFFLIGALLTAVSVLLSPMSSRLGIPILLIFLAVGILAGEDGPGGILFDDYSTAYLVSNLALAIILLDGGMRTRVASFRVALWPALSLATFGVAITTSITGMMAAWLFDLHWLQGLLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGSNDPMAVFLTVTLIAILANVDTEMSFSFMFISFIKQFGLGICLGLGGGWMLWKLVNLSKLADGLYSILVLSGGLIIYAASNKLGGSGILSIYLVGLFLGNKPTRGRHAILNVLDGMTWVSQIGMFLVLGLLLTPSDLVDILIPGFALAFGMILFARPVAVWISLLPFKSFSSRDRWFISWVGLRGAVPIILAVFPMMAGLPGAQLYFNLAFFVVLVSLLVQGASLTTAARLAKVELPPKPLPVSRSGVEIYPSSEWEVFVYRLSESKWCIGEPLKRLAMPDGTRIAAVFRNDTLLHPSGSTRLEAGDILCVLGQEKSLEALSNLFSQAPENKEVQRFFGDFFIETDVKLADLAPIYGLSLDNLADDMTVADLVVSQLGANPVLGDQFQWQSLHWVVAGLYEGKVTNVGIRLPTEHAL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GOT1A_HUMAN
Sequence: MISITEWQKIGVGITGFGIFFILFGTLLYFDSVLLAFGNLLFLTGLSLIIGLRKTFWFFFQRHKLKGTSFLLGGVVIVLLRWPLLGMFLETYGFFSLFKGFFPVAFGFLGNVCNIPFLGALFRRLQGTSSMV
What is the function of this protein?
May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
What are the official names of this protein?
Vesicle transport protein GOT1A, Golgi transport 1 homolog A, hGOT1b.
What is the protein family that this protein belongs to?
Belongs to the GOT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: PUR9_CUPNH
Sequence: MIKQALLSVSDKTGIVDFARELNALGVTLLSTGGTAKLLADSGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMAALAEHDIPTIDLLVVNLYPFQQTVAKDDCTLPDAIENIDIGGPTMLRSAAKNHRDVTVIVDPADYAVVLDEMRANANSVGYDTNFRLATKVFAHTAQYDGAITNYLTSLGADKSHQGRSAYPQTLNLAFDKVQEMRYGENPHQSAAFYRDLRAVDGALANYVQLQGKELSYNNIADADAAWECVKSFDAASGAACVIIKHANPCGVALGANALEAYDKAFKTDSTSAFGGIIAFNVELDETAAQAVARQFVEVLIAPSFSAGARAVFAAKQNVRLLEIPLGQGINQYDFKRVGGGLLVQSPDARNVQPSELRVVTRRHPNPKEMDDLMFAWRVAKFVKSNAIVFCGGGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVDAGATCVIQPGGSMRDDEVIAAADERGIAMVVTGTRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL14_THISH
Sequence: MIQMQTVLDAADNSGARKVQCIKVLGGSHRRYASVGDIIKVSVKDAIPRGKVKKGEVYNAVVVRTAKGVRRPDGSVVRFDRNAAVLLNNQLQPIGTRIFGPVTRELRGEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HGD_STRCO
Sequence: MSGDARKTAEGLAYLSGFGNEHASEAVAGALPEGRNSPQRAPLGLYAEQLSGTAFTEPRAHNRRSWLYRIRPSAAHPAFTRSGNGTIRTAPFNQAVPDPNRLRWNPLPVPGPATDFVEGLWTLGGNGDATQRTGMAVHLYHATASMDRVFSDADGELLIVPERGGLLLRTEFGLLHAEPGHVALIPRGVRFRVQLLDEDARGYVCENYGAPFQLPDLGPIGANGLANARDFRAPVAAYEDDESTPGPVEVVNKFCGNLWTAEYDHSPLDVVAWHGNHVPYVYDLRRFNVIGSISYDHPDPSIFTVLTSPSDTPGLAGVDFVVFAPRWLVGEDTFRPPYFHRNVMSEYMGLIEGAYDAKAEGFVPGGGSLHNMMSAHGPDRETFDRASAAELKPQRIDDGLAFMFETRWPVTLTPQAARAEHLQPGYDDVWQGLERHFRPLH
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: DNAK_HAEIN
Sequence: MGKIIGIDLGTTNSCVAVMDGDKARVIENAEGARTTPSIIAYTDNETLVGQPAKRQAITNPKNTLFAIKRLIGRRFESEEVQRDIKIMPFEITRADNGDAWVNVKGDKLAPPQISAEVLKKMKKTAEDFLGESVTEAVITVPAYFNDAQRQATIDAGKIAGLDVKRIINEPTAAALAFGLGSSKENQVIAVYDLGGGTFDISIIEIDNFDGEQTFEVLATGGNTHLGGEDFDNRVIDYIIDEFKKEQNIDLRNDAMALQRVKEAAEKAKIELSSAQSTEVNLPYITADATGPKHLALNITRAKLEALVEDLVASSIESLKAVLKDADKGVSEIHDIILVGGQTRMPLVQQKVAEFFGKEARKDVNPDEAVAIGAAVQGGVLKGDVKDVLLLDVTPLSLGIETMGGVMTTLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLEGINPAPRGMPQIEVTFDIDANGVINVSAKDKNTGKEQQIRIQASSGLSDEEIQQMVRDAEANADADRKFEEVVQARNQADGIAHATRKQIAEAGDALSVADKEKIEAAVAELETAAKGEDKAEIEAKIEAVIKASEPLMQAVQAKAQQAGGEQPQQSSAKDDGVVDAEFEEVKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DHAS_ECOLI
Sequence: MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAAPSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLRMKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVATYQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNFGVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQAFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRKLNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: RR14_AMBTC
Sequence: MARKSLIQRERKRQKLEQKYHLIRRSLKKEISKTPSLSDKWKIHGKLQSPPRNSAPIRLHRRCFSTGRPRANYRDFGLSGHVLREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS20_LACP7
Sequence: MANIKSAKKRIKVIETKTLRNKVIKSKVKTLVKKVEVAVAASDKDLATKSLKDAVVAIDKAASKGVYHKKNAARKVGRLAKAVNSIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YDFS_BACSU
Sequence: MIELEVVIRTVASFGLLLIAERILGKQTISQMTIFDFIAAITLGAIAAGLAYNTSIKPHNMAISFSIFVLTIFLISFLSIKNRKLRKFFAGDPTVLIQNGKILESNMRKMRYTLDYLNQQLREKEIFNIEEVLFAILETNGQLTVLRKPQFRHVTKQDLMIAVNQEQRLPIELIMDGEIIENNLKQNRLTESWLLEELRKRDIKVKETVYAVLLGNGDIYVDQYKDHISVPMDKE
What are the official names of this protein?
UPF0702 transmembrane protein YdfS.
What is the protein family that this protein belongs to?
Belongs to the UPF0702 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS4_PSYIN
Sequence: MIIPALDLIDGKVVRLYQGDYAQKTVYSDSPQSQFTIYNQQGADWLHLVDLDGAKDVTKRQLKVIASLIANTPAKIQIGGGVRTEQDVQDLLDAGAQRVVIGSTAVKEPAMVAGWMKKYGAEHIVLALDINIDAQGNKIVAVSGWQEASGQTIESLLETYLAVGLKHVLCTDISKDGTLSGSNVSLYKEMAAAYPQVAWQASGGIGSLDDIAAVARSGASGMIVGRALLEGKFTVKEAIFCWENA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ANASK
Sequence: MTGIGEQSIAEQVRSLLEPVLERDGYELVEVEWARLAGRWTLRVFIDKAGGVGIDDCQAVSKTVEPILDVADVIEPAYDLEVSSPGLDRPLRKPRDFDRYAGQRVHVKAYGPVAGTAPGAPARKHWTGVLKGFRDGAVELDVDGVLHRVPHDQIAKANLEYDVEGDLRRKD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.