PharMolix/UniProtQA huggingface dataset:
Protein: IDH_STAAN
Sequence: MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVENEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: RPOA_KORVE
Sequence: MLWKGFQKPKRLAFDSESLTDKYGHFWAQPFERGFGTTIGNALRRVLLSSIEGAAITAVKIEGVLHEFQSIPGVVEDATDIILNLKQIPFRLNGDAPKAIYLRAEQPGIVTSGMIETDADVEILDKDVYIATISEGGKLDMEMRLKKGRGYVSADKNFDEDLGLGFIPIDSVHSPVRKCNYSVEAARLGQITDYDKLSIELWTNGSVNPADALGLAAKLLKDHMNIFINFEEEIEASHAEDRKPEIRNENLNRSVEELELSVRSYNCLKNANIQTIGELVQKTEAEMLKTKNFGRKSLNEIKEILASMGLSLGMKIDEHGNAVAPPPGSQPAPSYGGYPGSYGTGGTFGGGGNYGGGGGFGGDNNPGF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PHAA_SYNY3
Sequence: MSIVTKSIVNADAEARYLSPGELDRIKAFVTGGAARLRIAETLTGSRETIVKQAGDRLFQKRPDIVSPGGNAYGEEMTATCLRDMDYYLRLVTYGVVSGDVTPIEEIGLVGVREMYRSLGTPIEAVAQSVREMKEVASGLMSSDDAAEASAYFDFVIGKMS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: TRPD_DESHD
Sequence: MTYAIHESLTLLSQKQNLPEELTFTVVQDLLSGELTPAQIGGLLLGLSLKGETPEEIAAFAQALRGAGLKIKAPAGTLDTCGTGGDRSGTFNISTTAAFVIAGAGVPVAKHGNRFASGRCGSADVLEQLGISLKATPESSERHLQHIGMTFLFAQVYHPAMAKVARERRELGIRTIFNLLGPLLNPAGAPYQLLGVSSPSLLPKMAKALQILGSKRAVVAVGEDGLDEVTLTGATQAILIDGGAIQPFIIRPEEYGLNLCSLQDLQGGTPAENGQITLRILQGKKGPQRDIVLLNAGTALYAANKAAGIREGIALAAESLDSGKALSILEKLKASA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NUOI_CHLT3
Sequence: MHEKNPKFKPTRLNFLERLYLPEVLKGLGYTFRQIFAPIFTTEYPDVKWQPPAVFRGRPVLVERDDKTGERCVACGLCSRVCPPMAISIQAEETELEQERHPATFEINMLRCIYCGYCEEVCPEEAIVMSDEYDITFNNRENAIMDKSKLLVPVARVQKRLDFLKEYKNKVRRPEEQVSNLEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECR_PECAS
Sequence: MQTSPLLESLMEALRCLPGVGPRSAQRMAFQLLQRNRSGGMRLAQALTQAMSEIGHCSDCRTFTEQDVCAICSNPRRQQNGLVCVVESPADIHAIEQTGQFAGRYFVLMGHLSPLDGIGPDDIGLGRLEERLQVESFNEVILATNPTVEGDATANYIAELCAQHGVMASRIAHGVPVGGELEMVDGTTLSHSLAGRQPFRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FEN_METTH
Sequence: MGVKLRDVVSPRRIRLEDLRGRTVAVDAANTLYQFLSSIRQRDGTPLMDSRGRVTSHLSGILYRTAAVMEREIRVIYVFDGRSHHLKGETVSRRADIRKKSEVEWKRALEEGDIDRAKKYAVRSSRMSSEILESSKRLLELLGIPYVQAPGEGEAQASYMVKMGDAWAVASQDYDCLLFGAPRVVRNLTLSGKLEDPEIIELESTLRELSISHTQLVDMALLVGTDFNEGVKGIGARRGLKLIREKGDIFKVIRDLEADIGGDPQVLRRIFLEPEVSEDYEIRWRKPDVEGVIEFLCTEHGFSEDRVRAALKKFEGASSTQKSLEDWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: PEPT_LACLL
Sequence: MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIKLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNTMVNALQLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIVPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVVK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, L9PepTR, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_HV1VI
Sequence: MGARASILSGGKLDEWEKIQLRPGGKKRYKMKHLIWASRELERFALDPGLLETSEGCQKIIRQLQPSLQTGSEELKSLFNTVAVLYYVHQRAGVTDTKEALDKLEEEQNKSQQKTQQAAADKGVSQNYPIVQNLQGQMVHQSLSPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPTDLNTMLNTVGGHQAAMQMLKDTINEEAAEWDRLHPVHAGPAPPGQMREPRGSDIAGTTSTLQEQIQWMTGNPPVPVGDIYKRWIILGLNKIVRMYSPVSILDIKQGPKEPFRDYVDRFFKVLRAEQASQDVKGWMTDTLLVQNANPDCKTILKALGTGATLEEMMTACQGVGGPSHKARVLAEAMSQANSAIMMQKSNFKGQRRVVKCFNCGKEGHIARNCRAPRKKGCWKCGREGHQMKDCTERQANFLGKIWPSNKGRPGNFLQSRPEPTAPPAESFGFREEITPSPKQEQKDGELYPPLASLKSLFGNDP
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: RIMM_BAUCH
Sequence: MPVNPVVLGTISSAYGISGWLNIISFTQNAASIFEYQPWFIKKLNTWLDVILDEWKYNYHNKLIIKINSIENREAAQLFANCNIIVDASQLPTLSDGDYYWKDLIGCQVETINSYQLGKVIDLIETGSNDVMVVQANQQHSTKINELLIPFIYGQVIKNVDLATHIIKVDWDPEF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BACC0
Sequence: MTIKRKKVSVIGAGFTGATTAFLLAQKELADVVLVDIPQLENPTKGKALDMLEASPVQGFDANIIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVLTNPVDAMTYSVFKEAGFPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGGHGDDMVPLVRYSYAGGIPLETLIPKERLEAIVERTRKGGGEIVGLLGNGSAYYAPAASLVEMTEAILKDQRRVLPAIAYLEGEYGYSDLYLGVPVILGGNGIEKIIELELLADEKEALDRSVESVRNVMKVLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: PLSX_CUPNH
Sequence: MTIKIAIDCMGGDHGVSVTVPAAISFLSRHDDAEMVLVGLPDAIRTQLKKLHALDHPRVTIVEATEVITMDDPVEVALRKKRDSSMRVAVTQVKEGLAGACISAGNTGALMAVSRYVLKTLEGIERPAIATTIPNEQGWGTTVLDLGANADCEPEHLLQFARMAEAMVAVVDHKEHPTVGLLNIGEEVIKGNEVVKRAGELLRASELNFYGNVEGNDIFKGTTDIVVCDGFVGNVALKSTEGLAKMIGSMIKEEFTRSWFTKLLAAVAMPVLSRLARRLDPARYNGASLLGLRGLVIKSHGSADAHSFEWAIKRGYDAAKNGVIARITRAFADKSSAAGAAQPAPETEVPGAHPSPHVA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DNJB6_MOUSE
Sequence: MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGIHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQPTPALAPGPAPAPVRVPSQARPLAPTPAPTPAPTPAPAPAQTPAPSVSTRPQKPPRPAPTAKLGSKSNWEDDEQDRQRVPGNWDAPMTSAGLKEGGKRKKQKQKEDLKKKKSTKGNH
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed:18373498).  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily B member 6, Heat shock protein J2, HSJ-2, MRJ, mDj4.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
Protein: CG21_EMENI
Sequence: MNENDENGPSTRLTRAKAAALTTDAPAANGALKKPLQTKKAATGANGTQRKRAALGDVSNVGKADNGETKDAKKATSKTGLTSKATMQSGGVQKLSRSNLSRTAVGAKDNNVKKPATEAKRPGSGSGMGSAMKRTSSQKSLQEKTIQQEEPPRKKVDIEKVVEKQAEAVSVKGDVKAGAQTEELEKPQDFVADLDTEDLDDPLMAAEYVVEIFDYLRELEMETLPNPDYIDHQPDLEWKMRGILVDWLIEVHTRFRLLPETLFLAVNIIDRFLSAEVVALDRLQLVGVAAMFIASKYEEVLSPHVANFSHVADETFSDKEILDAERHILATLEYNMSYPNPMNFLRRISKADNYDIQTRTLGKYLMEISLLDHRFLGYPQSQIGAAAMYLARLILDRGPWDATLAHYAGYTEEEIDEVFRLMVDYLHRPVCHEAFFKKYASKKFLKASIMTRQWAKKYHHLYIDSALTEPYNSIKDNE
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-B.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: PLLP_MOUSE
Sequence: MAEFPSKVSTRTSSPAQGVGASVSALRPDLGFVRSALGVLALLQLALGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPLVLLIFFVAATVLYITAFIACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGVSAFFSFQAWRGVGSNAATSQMAGGYS
What is the function of this protein?
Appears to be involved in myelination.  Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity).
What are the official names of this protein?
Plasmolipin, Plasma membrane proteolipid.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOI1_GEOSL
Sequence: MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHDKAKCVACYLCPTVCPAKCITVEAGEDATHDKYAERYEIDMLRCIFCGYCVEACPVDALKMTGQFELANYKREDFIFVKERLLEKK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SDHD_BACCZ
Sequence: MKEIETLKEEYPLLNKLIATEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIAKVFPETKETKGIIESPLLKIPSMKQALEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQHGMLTEEDDYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGRRQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELKIVVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYLQKQQLMEKVQKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: AMY1_ORYSJ
Sequence: MQVLNTMVNKHFLSLSVLIVLLGLSSNLTAGQVLFQGFNWESWKENGGWYNFLMGKVDDIAAAGITHVWLPPPSHSVGEQGYMPGRLYDLDASKYGNEAQLKSLIEAFHGKGVQVIADIVINHRTAEHKDGRGIYCLFEGGTPDSRLDWGPHMICRDDPYGDGTGNPDTGADFAAAPDIDHLNKRVQRELIGWLDWLKMDIGFDAWRLDFAKGYSADMAKIYIDATEPSFAVAEIWTSMANGGDGKPNYDQNAHRQELVNWVDRVGGANSNATAFDFTTKGILNVAVEGELWRLRGEDGKAPGMIGWWPAKATTFVDNHDTGSTQHLWPFPSDKVMQGYAYILTHPGNPCIFYDHFFDWGLKEEIERLVSIRNRQGIHPASELRIMEADSDLYLAEIDGKVITKIGPRYDVEHLIPEGFQVVAHGDGYAIWEKI
What is the function of this protein?
Important for breakdown of endosperm starch during germination.
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase, Alpha-amylase isozyme 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: GYRB_STRP3
Sequence: MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEGLHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQVKTGRPAVETVFTVLHAGGKFGGGSYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVVADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKRSGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQETVMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVISVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKARIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNREFQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTDADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQLKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVFDMLMGDRVEPRRDFIEENAVYSTLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTD_HUMAN
Sequence: MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ
What is the function of this protein?
Supplies the nucleotide substrate for thymidylate synthetase.
What are the official names of this protein?
Deoxycytidylate deaminase, dCMP deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: DCUP_MYXXD
Sequence: MNDRLLRAARRQPTDTTPVWLMRQAGRYLPEYRAIRGNIAFLDLCKHPDLAAEVTVQPVTRLGVDAAIIFSDILIPVEAMGITLELGDKGPHFPDPVRSAADIDKLGVPDPVEGTGFVAEAIRRTRKALNDSVPVIGFAGAPFTLAAYMVEGGGSKSYILIKRLMFEQPELAHRLFGKLTDTLIPYLKMQVEAGASIVQIFDSWGGALSPWDYERFCIPYLKRMVSELKATGVPVIVFGVGMSSHLSLLKSTGADVVGLDWTLPMDEGRKVLGPDVAVQGNLDPLHLFLPREELDGRVKDILRRAGPEGHIFNLGHGILPPTDPDAAKFLVEAVHRHGVALRQGTLGA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_ANOFW
Sequence: MNANWNFDNSYARLPERFFTRIYPTPVSDPKLVVLNHSLAKELGLNAEVLASEEGVAVFAGNRVPEGAEPLAQAYAGHQFGYFNMLGDGRAILLGEHVTPSGERVDIQLKGSGRTPYSRGGDGRAALGPMLREYIISEAMHALGIPTTRSLAVVTTGEVVMRETELPGAILTRVAASHLRVGTFQYAGRFLSKEELQALADYAIKRHYPNGEHASNRYVFLLEEVMKKQAALVAKWQLVGFIHGVMNTDNMTISGETIDYGPCAFMDVYDPETVFSSIDTQGRYAYGNQPYIAGWNIARFAESLLPLLHDEEEKAIEIAQKVIEQFPALYETYWLQGMRAKLGLWTEEAEDKKLIGELLHLMYTHRLDYTNTFRSLTLEEWHFCEQELRDWYTRWQQRIARQDMTKEEVYECMRQNNPAIIPRNYRVEEALAAAVEHGDDTVMERLLHVLSDPYAYMEEQEEYAKTPEPSDRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ZC11C_HUMAN
Sequence: MPNQGEDCYFFFYSTCTKGDSCPFRHCEAALGNETVCTLWQEGRCFRRVCRFRHMEIDKKRSEIPCYWENQPTGCQKLNCAFHHNRGRYVDGLFLPPSKSVLPTVPESPEEEVKASQLSVQQNKLSVQSNPSPQLRSVMKVESSENVPSPKHPPVVINAADDDEDDDDQFSEEGDETKTPTLQPTPEVHNGLRVTSVRKPAVNIKQGECLHFGIKTLEEIKSKKMKEKSEEQGEGSSGVSSLLLHPEPVPGPEKENVRTVVRTVTLSTKQGEEPLVRLGLTETLGKRKFSTGGDSDPPLKRSLAQRLGKKVEAPETNTDETPKKAQVSKSLKERLGMSADPNNEDATDKVNKVGEIHVKTLEEMLLERASQKHGESQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEEEHRQQEAERQKSKKDTTCIKLKTDSEIKKTVVLPPIVASKGQSEEPAGKTKSMQEVHMKTVEEIKLEKALRVQQSSESSTSSPSQHEATPGARLLLRITKRTWRKEEKKLQEGNEVDFLSRVRMEATEASVETTGVDITKIQVKRCEIMRETRMQKQQEREKSVLTPLQGDVASCNTQVAEKPVLTAVPGITWHLTKQLPTKSSQKVEVETSGIADSLLNVKWSAQTLEKRGEAKPTVNVKQSVVKVVSSPKLAPKRKAVEMHPAVTAAVKPLSSSSVLQEPPAKKAAVDAVVLLVSEDKSVTVPETENPRDSLVLPLTQSSSDSSPPEVSGPSSSQMSMKTRRLSSASTGKPPLSVEDDFEKLTWEISGGKLEAEIDLDPGKDEDDLPLEL
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 11C.
Protein: Y3466_MYCTO
Sequence: MGSGSRERIVEVFDALDAELDRLDEVSFEVLTTPERLRSLERLECLVRRLPAVGHALINQLDAQASEEELGGTLCCALANRLRITKPDAALRIADAADLGPRRALTGEPLAPQLTATATAQRQGLIGEAHVKVIRALFRPPARRGGCVHPPGRRSRPGRQSRSISSRRAGPLRPAGHGLATPRRRPHRHRTRPQTRHHPEQPALRRYVTAKWLPDPPSAGHL
What are the official names of this protein?
Uncharacterized protein MT3572.
What is the protein family that this protein belongs to?
Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
Protein: ALR_CERS4
Sequence: MATATLTIDLDAIAANWRALDQMTASDCQTGAVVKADSYGLGAAKVAHALARAGARRFFVATCEEGADVRRALGSGPQICVFSGHMEGDTALIRDFDLTPMLNSIDQLTRHFEALGGQPFGLQLDSGMNRLGLEPGEWEAVAGFALEAGPELLMSHLACSDDPDHPMNAEQLGAFRAMTDGTGVPRSLSATGGILLGPAWHFELTRPGIGLYGGRPFENARPVVRLSLPVIQVREVEIGEPVGYSNTWTAEHTSTIATVAAGYADGLPRTLSSRATLYAGRVPCPLVGRVSMDLITVDVSHLPEVPETLDILGPHQTPDDLADTAGTIGYEILTSLGRRYQRRYGALAA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: Y563_RICCN
Sequence: MLKKIIILFLGMFLLSACTDNFRSYFQRSANNRLVDSKGAKGGKRKPVYNNKYITLAKKNIVEDNLDDDNDDDYDSDSPLRGERIDPVKRNREMYLKMIKRDIARQKAEAGFAESDDDMTLSRANKKVRKDDSDKEKKIQEELNQIKAMLRETKRDISKYTCPNAVVNQNYAPPVTNYEPVNYPPVKNSKPYNNNSKVKQKFILEDDDNGSNACSI
What are the official names of this protein?
Uncharacterized lipoprotein RC0563.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: AROD_KLEP3
Sequence: MTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFTQVRDMTQVMAALAEIRGALKALPLLFTFRSKKEGGETEISDEAYFALNREAARSGLVDVIDIELFNDEAQIHALVDDAHAAGVKVIMSNHDFHKTPAQEDIIYRLRRMQDLGADLPKIAVMPQSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPGQIAIAKLREVMDILS
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: IGS11_BOVIN
Sequence: MTCRGSPLAPLLLFSLHGVAASLEVSESPGSVQVARGQTAVLPCTFTTSAALINLNVIWMVIPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSSAKAFHMEISSSENNTLTSSNTYNSRYWSSNPKAHRNTESFGHFGDLRQSFSLHSGNASVPAIYANGSHLAPAPHKTLVVTANRGSSLPAVSRSNGSVSRKARPPPVPSLHTHSYTVSQATLERIGAVPVMVPAQSRAGSLV
What is the function of this protein?
Functions as a cell adhesion molecule through homophilic interaction.  Stimulates cell growth (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 11, IgSF11.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL9_SHEB2
Sequence: MNVILLDKIANLGNLGDQVSVKAGYARNFLLPQGKAVVANESNVKVFEARRAELEAKLAAELAAANLRAEKITALEAVVIASKAGDEGKLFGSVGNRDIADAVTAAGVELAKSEVRLPLGALRTTGDFEVEVQLHTEVKAVVKVSVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.