PharMolix/UniProtQA huggingface dataset:
Protein: H17A3_CYRHA
Sequence: MTTVGVSLFRRSPEKITMKIATFLGLSFLLIASYFLICEAQHPGFQELLILEENMRDPENSKERSCAKPRENCNRMNILCCRGECVCPTFGDCFCYGD
What is the function of this protein?
Inhibits with low potency Kv1. 2/KCNA2 and Kv1. 3/KCNA3 voltage-gated potassium channels(PubMed:29483648).
What are the official names of this protein?
Hainantoxin-XVII.3, HNTX-XVII.3, Peptide F2-20.97.
What is the protein family that this protein belongs to?
Belongs to the hainantoxin family. 17 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_CUPMC
Sequence: MIDWITSQGHDIFGMYWTPLWILIRAVLIVVPVLLCVAYLILWERKLIGWMHVRIGPNRVGPLGLLQPIADVLKLLLKEVMFPSQINRGMYLVAPLMVLMPAVAVWAVIPFQAEVVMADINAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQMVSYEIAMGFALVTVLMVSGSLNLSHIVNAQNTGYFANMGLNLLSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEIVAGHMIEYSGMTFALFFLAEYINMIIISTMTSLMFLGGWAPPFSSALTNAIPGFFWLVIKVFLLLSVFIWIRASFPRYRYDQIMRLGWKIFIPLTVAWLIIVAIWIKSPWNIWH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPF_HAEIG
Sequence: MIRIGHGFDVHAFGEDRPLIIGGVEVPYHTGFIAHSDGDVALHALTDAILGAAALGDIGKLFPDTDMQYKNADSRGLLREAFRQVQEKGYKIGNVDITIIAQAPKMRPHIDAMRAKIAEDIQCDIEQVNVKATTTEKLGFTGRQEGIACEAVALLIRQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL15_SACS2
Sequence: MVVRREKKSRKMRGSRTMGWGIRGQHRDRGSQGGRQIGMHKEKWSWLVKYGKGWYGKHGFRNPTTKLTSAISLRKLNELLESGYIKIKEMDGKKIVDLNELGYNKLLGGGSISIPVTIKVGKATNKAIQKVKEMGGEVILSPTE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: AROK_OCEIH
Sequence: MGKFPLREQSIVLIGFMGVGKTTIGKTVAKKLYRDFIDIDEEIEKRFKMPTKDIFRLYGEKTFRNAEKDIISEICQQRLKVVSLGGGAFLQKEIQEICLNSSIIFYLDLSWDRWKDRIELLMESRPVLQGKTMKEMKQLYEDRKPIYEQHHSRVDTDYHEIEEVADYIAESLKLAWDIYEPTS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO12_MAIZE
Sequence: MSWQAYVDEHLMCEIEGHHLTSAAIVGHDGAVWAQSTAFPQFKTEEMTNIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQAMVVGIYDEPMTPGQCNMVVERLGDYLLNRA
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-12, Pollen allergen Zea m 12, Pollen profilin variant 7.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HM1A_PHLSP
Sequence: MKVSVLITLAVLGVMFVWTSAAEQEDHGSDRRDSPALLKNLLGEEVFQSEERACRELLGGCSKDSDCCAHLECRKKWPYHCVWDWTIGK
What is the function of this protein?
Gating-modifier toxin that inhibits voltage-gated sodium channel Nav by shifting the threshold for channel activation to more positive potentials.  This toxin moderately inhibits human Nav1. 7/SCN9A (IC(50)=459 nM) and weakly inhibits hNav1. 2/SCN2A and hNav1. 5/SCN5A (<20% inhibition at 1 uM peptide).  Inhibition of Nav1. 7 is voltage-dependent, with lower inhibition at more positive test pulses.
What are the official names of this protein?
Mu-theraphotoxin-Phlo1a, Mu-TRTX-Phlo1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 39 (Jztx-34) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAD51_USTMA
Sequence: MSQNAQDPAQIGEDDMGEAFGPLPVSKLEEFGISSSDCKKLAESGYNTVESIAFTPKKQLLLVKGVSEAKADKILAEAARLVPMGFTTATEFHARRNELISITTGSKNLDAILGGGMETGSITELYGEFRTGKSQLCHTLAVTCQLPVDMGGGEGKCLYIDTENTFRPTRLLAVAERFGLNGEEVLDNVAYARAYNADHQLQLLMQASAMMAESRFSLLIVDSLTSLYRTDFSGRGELSARQMHLAKFLRGLMRLADEFGVAVVITNQVVAQVDGATAFTADAKKPIGGNIVAHASTTRLSLRKGRGNQRICRIADSPCLPEADAVFAIGPEGIIDPVD
What is the function of this protein?
Required both for recombination and for the repair of DNA damage caused by X-rays.
What are the official names of this protein?
DNA repair protein RAD51.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_LACDB
Sequence: MIDVNKFESMQIGLASPNKIRSWSYGEVKKPETINYRTLKPEKDGLFDERIFGPTKDYACACGKYKGVRYKGIVCDRCGVEVTTSHVRRERMGHIELAAPVTHIWYFKGIPSRMGLVLDVSPKQLEEVIYFAAYIVIDPGDTGLEAKQLLTEAEYREEKAKYGNRFVAKMGAEAIRDLLKQVDLDKEVTALKAELQTLKGQKRTRAIRRLDILDAFRNSGNKPEWMVMETVPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKKLLDMHAPGLIVQNEERMLQEAVDALIDNGRRGRPVVGPGNRPLKSISHMLKGKQGRFRQNLLGKRVDYSGRSVIDVSPELKFYQCGVPRPMALELFKPFVMRELVRRGIASNIKNAKRKIDREDDDIWDVLEYVIKERPVLLNRAPTLHRLSIQAFEPVLVPGKALRLHPLACEAYNADFDGDQMAIHVPLSDEAVAESRLLMLAAHHILTPKDGTPIVTPSQDIVLGNYWLTQAEIGREGEGMIFATPEEATIAYNNGDIHYHTIIGVSAASMPKKDWGAGHEDSIFVTTYGRLVFNSLFPDDYFYINEPTQDNLKQPMADKYFLEDGQDIQDKIAEIGQDLVATPFKKGFLGDTISEIYKRYRVQRTSEYLDDLKEMGYSASTISGLTIGMADIPETKTKDALVAEARKQVKQVSKMFRRGKLSDKERHDNIIKIWTDCKDAVQQEIAEFKDQKNPISVMQQSGARGNISNFTQLAGMRGLMATPSGELFEIPVISNFKEGLTVLELFMSTHGARKGMTDTALKTAQSGYLTRRLVDVAQDVIIREDDCGTDRGITAKAIVDKDAGLIESLYDRLVGRFTNRTIRDPQTGEVICSKGVLMDEQMAQKIVDAGVQEVQIRSILTCNTSHGICRKCYGRNLATAEEVEIGEAVGTVAAQSIGEPGTQLTLRTFHTGGVAGAEDITQGLPRVQELFEARNPKGRAVISEVDGVVDKIESNAAEHLQEITVKGKIDTRVYTIPYTAKPAVQEGDEIHRGDKLIPGSIDPKELIKVTDTLTTEEYILAEVQKSYRTQGVDLADKHAEVLTRQVLQKVRVLDPGETDILPGEVMDIAEFRDRNRDVIISGGIPATAQAYILGITKAALETNSFLSAASFQETTRVLTDASIRGKNDPLLGLKENVIIGKIIPAGTGMPIYRDQVPKADVQQPDSVYSIADLEKKMEDENKETESK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ADE_STUS1
Sequence: MHDWLNNLPKAELHLHLEGSLEPELMFRLAERNKIALPWNDVEALRSAYNFGNLQEFLDLYYAGADVLRTEQDFYDLTWAYLQKCEEQNVVHTEPFFDPQTHTDRGVPFEAALNGISAALADGRELLGISSGLILSFLRHLPEEEAFKTLEQALPYRNAFFAVGLDSSEVGHPPSKFQRVFDKARGEGLLTVAHAGEEGPPEYIWQALDLLKVSRIDHGVRAAEDPKLIARLIEEQIPLTVCPLSNTKLKVFADMRQHNILDLLEQGVKVTVNSDDPAYFGGYVTENFVALHESLGMTEAQARRLAQNSLDARLAY
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: DXS_RIPO1
Sequence: MHISDITHPNQLHGLSIRQLEDVARQIREKHLQTIAATGGHLGPGLGVVELTIALYQTLDLDRDKVTWDVGHQAYPHKMLTGRYKNFHTLRQKDGIAGYLKRCESKFDHFGAGHASTSISAALGMALARDAQGEDYKVVAVIGDGALTGGMALEAINHAGHLPHTNLMVVLNDNEMSISPNVGAISRYLNKVRLSDPVQFLADNLEEQFKHLPFFGDSLSPEMERVKEGMKRLAVSKVGAVIEELGFKYFGPIDGHNLQELISTFKQAHKVTGPVLVHVATVKGKGYELAEKDQVGYHAQSPFNLATGKAIPSSKPKPPSYAKVFAHTLTTLAENNPKIIGITAAMATGTGLDKLQAKLPKQYIDVGIAEQHAVTLAGGLACEGMRPVVAIYSTFLQRAYDQVLHDVCIQNLPVFFCMDRAGIVGADGPTHQGMYDIAYLRCIPNMTIMAPKDEAELQRMIVTGVNYTDGPIAMRYPRGNGIGVPLMEEGWEPLPIGKGEILRNGDDLLILGYGTMVNTALQAAETLREHGIEATVVNARFVKPLDTELILPLAQRIGKVVTLEEGCLMGGFGSAVAEAFSDHNVLVPLKRFGVPDRLVDHATPDQSKADLGLTSPQIAEQILQVFFSNRQPSMVS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NDUB4_PANTR
Sequence: MSFPKYKPSSLRTLPETLDPAEYNISPETRRAQAERLAIRAQLKREYLLQYNDPNRRGLIENPALLRWAYARTINVYPNFRPTPKNSLMGALCGFGPLIFIYYIIKTERDRKEKLIQEGKLDRTFHLSY
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4, Complex I-B15, CI-B15, NADH-ubiquinone oxidoreductase B15 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: 094L_FRG3G
Sequence: MDPEGMMYGFGVSFGISWAILKLFGREKKGKDRPREDGTQQQPSESKGEAACRDAAYRITGKRFEKIRHKGIVNPDTGRALELDCYSKSLKTAIEYQGRQHYEYVSVFHKGGRQDLRKQHERDCYKRAACQKLGIKLIEVPYTVKDIEGYLRKVL
What are the official names of this protein?
Uncharacterized protein 094L.
Protein: GDT13_ORYSJ
Sequence: MDPNPRLLILLVLLAFSATVAVAEDGESTGGSKVSLGRRAGGFLHGLKKEAVVEGDHGVALDEVGPGLFDALFASLSMILVSEIGDETFIIAALMAMRHPKSIVLSGALSALYVMTVLSTGLGRIVPNLISRKHTNSAATVLYLFFGLRLLYIAWKSDPKGSQKKEMEEVEEKLESGQGKSTLRRFFGRFCTPIFLEAFILTFLAEWGDRSQIATIALATHKNAIGVAVGASLGHTVCTSLAVIGGSMLASKISQRTVATIGGVLFLGFSVSSYFYPPL
What are the official names of this protein?
GDT1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OADC_PSEA8
Sequence: MHRASHHELRAMFRALLDSSRCYHTASVFDPMSARIAADLGFECGILGGSVASLQVLAAPDFALITLSEFVEQATRIGRVARLPVIADADHGYGNALNVMRTVVELERAGIAALTIEDTLLPAQFGRKSTDLICVEEGVGKIRAALEARVDPALTIIARTNAELIDVDAVIQRTLAYQEAGADGICLVGVRDFAHLEAIAEHLHIPLMLVTYGNPQLRDDARLARLGVRVVVNGHAAYFAAIKATYDCLREERGAVASDLTASELSKKYTFPEEYQAWARDYMEVKE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
Protein: KLK14_HUMAN
Sequence: MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK
What is the function of this protein?
Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity.  May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11.  May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3.  May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface.  May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
What are the official names of this protein?
Kallikrein-14, hK14, Kallikrein-like protein 6, KLK-L6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein: AROC_CLAM3
Sequence: MLRWLTAGESHGPELIAVLEGLPAGVPVSLDGIRADLARRKLGYGRGARMAFEQDELSLSTGVVHGRTLGSPIAVRIGNTEWPKWVDIMSPEPVDPEKLQGARAAALTRPRPGHADLVGMQKYDFDEARPVLERASARETAARVALGAVARAFLAELGITLVSHTLSIGPVRVPEGAPLPTPADVDALDADPLRCFHPETSARMVAEVDDTKSSGDTVGGVVEVLAYDLPPGLGSHVHWDRRLDSKLAAALMGIQAIKGVEVGDGFLTTTRRGSEAHDELFSTDAGIGRSTDRAGGTEGGMSTGTVLRVRAGMKPIATVPRALRTIDTATGGAAPANHQRSDVCAVPAAGVVAEAMVALTLADAVLEKFGGDSVGETLRNLRGYLDAIPEGRRTGADLVDEADAAPPAAPEA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y325_BUCBP
Sequence: MFLIDSHCHLDLLNYNKIHTGIQDVLNKSKKKHVNVILTVSTSIENFCYLLKFIKGNRNVLLSCGIHPHYIPENKNEILKLKKYSNNEKVVAIGETGLDYYRNNDNKKLQQILFREHIKTSITLKKPLLIHTRNSINDTINILKEENSKQCIGVLHSFTEDMHSARILLNMGFYISFSGIVTFKNSKIVHETAKFVPIDRILIETDSPYLSPVPYRGIENQPAYLYDTMLYIAQLKNMSPECFAIQTTKNFLKLFNLPSYFTNMS
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase bbp_325.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: SRR_ORYSJ
Sequence: MGSRGGSGGDGAESHGYAADIHSIREAQARIAPYVHKTPVLSSTSIDAIVGKQLFFKCECFQKAGAFKIRGASNSIFALDDDEASKGVVTHSSGNHAAAVALAAKLRGIPAYIVIPRNAPACKVDNVKRYGGHIIWSDVSIESRESVAKRVQEETGAILVHPFNNKNTISGQGTVSLELLEEVPEIDTIIVPISGGGLISGVALAAKAINPSIRILAAEPKGADDSAQSKAAGKIITLPSTNTIADGLRAFLGDLTWPVVRDLVDDIIVVDDNAIVDAMKMCYEMLKVAVEPSGAIGLAAALSDEFKQSSAWHESSKIGIIVSGGNVDLGVLWESLYKR
What is the function of this protein?
Catalyzes the synthesis of D-serine from L-serine (PubMed:19249065, PubMed:20564571).  Has dehydratase activity towards both L-serine and D-serine (PubMed:19249065, PubMed:20564571).
What are the official names of this protein?
Serine racemase, D-serine dehydratase, D-serine ammonia-lyase, L-serine dehydratase, L-serine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: RL10_STRZT
Sequence: MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: DOPP1_HUMAN
Sequence: MAADGQCSLPASWRPVTLTHVEYPAGDLSGHLLAYLSLSPVFVIVGFVTLIIFKRELHTISFLGGLALNEGVNWLIKNVIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSLGLLAVAFLVSYSRVYLLYHTWSQVLYGGIAGGLMAIAWFIFTQEVLTPLFPRIAAWPVSEFFLIRDTSLIPNVLWFEYTVTRAEARNRQRKLGTKLQ
What is the function of this protein?
Required for efficient N-glycosylation.  Necessary for maintaining optimal levels of dolichol-linked oligosaccharides.  Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate.  Does not act on phosphatidate (By similarity).
What are the official names of this protein?
Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the dolichyldiphosphatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMA_FRAP2
Sequence: MQYKTKAKKSLGQNFLQDENIIRKIVQLANIKKDDIVLEIGPGLGALTRYILKCSDNVNVVEFDASVIDTLLQNCQKYGEPKVFNEDFLKFDLDIVRADSQQKLKLIGNLPYNISSPILFKVIEQSDKIIDAHFMLQKEVVERIISQPNSKTYGRLSVILQYHFDCSMILNIPPEVFYPQPKVDSAILRLKPKANKLVINDYIFFENIVKQSFAQRRKTLHNNLKGILKELDIDPNTLPVDTKLRAENLSMEDFVSLVNFLK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_LISIN
Sequence: MPEITVRAKSKTYPVYINEFALTDVKEQWTKSLAKYSHVFVLTDEHVANLHKAKLDAVLADLPVVTYYVAPNGEEAKTFRVYEDVMTKMIETGLDRKAVLIAFGGGVIGDLGGFVAATYMRGIPFYQVPTTVLAHDSAVGGKVAINHPLGKNMIGNFYQPEAVIYDTQFFATLPEREMRSGFAEMIKHALISDHALLTALMDTFTEPKDFYTKDLTPFLQRGIEIKANIVAQDETEQGVRAYLNFGHTFGHALEAYGNFGKWLHGEAITYGMIYALTMSETVYGLDFDLAKFTTWLERLGYNTTFDVTVPFSNILDNMRHDKKTTFNEISMVLLEDIGKPVIFKAEDELIFDTYKSVMRNGGDLF
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNQ1_HUMAN
Sequence: MAAASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGALYAPIAPGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGAHITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS
What is the function of this protein?
Non-functional alone but modulatory when coexpressed with the full-length isoform 1.
What are the official names of this protein?
Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv7.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Early endosome. Membrane raft. Endoplasmic reticulum. Basolateral cell membrane. Note=Colocalized with KCNE3 at the plasma membrane (PubMed:10646604). Upon 17beta-oestradiol treatment, colocalizes with RAB5A at early endosome (PubMed:23529131). Heterotetramer with KCNQ5 is highly retained at the endoplasmic reticulum and is localized outside of lipid raft microdomains (PubMed:24855057). During the early stages of epithelial cell polarization induced by the calcium switch it removed from plasma membrane to the endoplasmic reticulum where it retained and it is redistributed to the basolateral cell surface in a PI3K-dependent manner at a later stage (PubMed:21228319).
Protein: GPMA_CHLPD
Sequence: MIKLVLLRHGESQWNRENRFTGWHDIDLTENGRNEAFQAGRLMKEAGLVFDMAYTSVLKRAIRTLWNAMDSMDLMWISVFKSWRLNERHYGALQGLNKSETSRKYGEEQVLVWRRSYDTPPPLLEKSDARYPGTDPRYGDLSEAEIPLSECLKDTVERFLPIWHETIAPQLRKGKRVIIVAHGNSLRALVKYLDNISEEDIVGLNIPTGIPLVYELDDDLKPLKNYYLGDQEALKKAVDAVAGQSKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: YOR3_FIVSD
Sequence: MLDRNSKSVLVAFYRSGNIFRYNQCSDSMETSTISSPSRRIRNNFLGLLGTRGARLSRLSWGNDTSKS
What are the official names of this protein?
Uncharacterized protein ORF3, ORFD.
Protein: METX_METTH
Sequence: MMEEIPASYFKIEEFQFESGEKIQEAPVEYRTTGKPSLDDMGVIDNAVIYIHGWSGDCSSVRRIAALTEPGGALENFFVISISSLGSPGSASPSTTAMGKDFPEYTILDMVNFQRQFLDEKFGIRKVRGVIGTSMGGFQALQWAAEYPDEMEFLIPLVTSWQVRGINYALFSYMNHLIEGDPEFRAGTRPERALSLASMLMYLHGLSREYYQGLENAELESSMMDMGSEGALMDPYDVIWRNRAAMKHDLSGKLESIRARTLIFGVNQDRYFPPELDTIPMAQLIPKAELVLFDSECGHLGVNEIGKYNEIIVSFIGGD
What are the official names of this protein?
Probable acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BACCN
Sequence: MARKTNTRKKRVKKNIETGVAHIRSTFNNTIVTLTDTHGNAISWSSAGALGFRGSRKSTPFAAQMAAETAAKAAMEHGLKSLEVTVKGPGAGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.