PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_XANOP
Sequence: MKDLLNLFNQQRQTLDFDAIKIALASPDLIRSWSYGEVKKPETINYRTFKPERDGLFCAAIFGPIKDYECLCGKYKRMKHRGVVCEKCGTEVTLAKVRRERMGHIDLASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFEAYVVTEPGLTPLERRQLLTEEQYLTARQEYNDDFDAAMGAEAVYELLRTIDLQSEMTRLREEIASTGSETKLKRLTKRIKLIEAFLESGNRPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLRRLLELNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLKLHQCGLPKKMALELFKPFVFAKLQRRGLATTIKAAKKLVEREEAEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMSRALENKKGEGMVFANTSEVKRAYDNRVVELHAKVKVRITQVDVDAVDGKRTSGTSIVDTTVGRALLSEILPEGLPFQLANTEMTKKNISRLINSSYRLLGLKDTVVFADKLMYTGYAYATRAGVSIGIDDMLIPDEKKGILTEAEAEVLEIQEQYQSGLVTAGERYNKVVDIWSRTSERIAKAMMDTIGTEKVENAKGETIDQKSMNSLYIMADSGARGSQAQIRQLAGMRGLMARPDGSIIETPIKANFREGLNVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITEIDCGTTEGLIMTPIVEGGDVVEPLKERVLGRVVAEDVYLPGNDEEPIVTRNTLLDEAWVAKLEDASVQSVKVRSTISCESSFGVCARCYGRDLARGHQVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAVDNITVKTTGSVKFNNLKSVAHASGSLVAVSRSGELSVLDGHGRERERYKLPYGATITAKDGDAVKAGQSVANWDPHNHPIVSEVAGFIRFIDFVDGVTVIEKTDELTGLASREITDPKRRGAHAKELRPIVRIVDGKGNDLTIPNTDLPAQYLLPPRSIVNLQDGAAVGVGDVVAKIPQEASKTRDITGGLPRVADLFEARKPKDPAILAERSGIISFGKDTKGKQRLIIKDTDGSEHEELIPKYRQIIVFEGEHVTKGETVVDGEPSPQDILRLLGVEPLAAYLVKEIQDVYRLQGVKINDKHIEVITRQMLRKVEIVDQGNSKFLNGEQVERQRVIEENARLVKRNELPAKYDPVLLGITKASLATESFISAASFQETTRVLTEAAVRGTRDNLRGLKENVIVGRLIPAGTGLAYHAGRRKASGLTDSEMETLSGKPAGAEPVAALADAGADEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: JBP1A_TRYCC
Sequence: MKQKRGKQDVKMLESAPPQLLPKKGRLEISELAPQQRTIRTAEEIETAYNEAVRKHPFYDNADHTIDFHDATVFRDARGVVGGVFLPGALPAFAATMAADVLRPAAVRTSLRSNMFGGFAPLSGIAGYFDYRGSPVELKCRKTSFTYENVHSWPNVFPMIDYVSAIYKAVFPEQWAAQDAAVPDIVRIHGSPFSTLTVNQQFRTASHTDAGDFDMGYGLLAVLEGKFEGLSLALDDFGVCFRMQPRDILIFNTHFFHSNTEPELNHPRDDWSRLTCVCYYRAALGEPACVAEYERRLARAKEIGASPPPAVDAILQKDNGNNFNKPAPTFPYLLTPFGGAASVCSLHCCTAKLLRLHELLLENPTLEVILFGESLRTDDGLPRREKEQLISVHLPVVVKMSPSGGFSELGGALKAAEEKQYFFEEKYLADELGPDLMSMWTQSRAHWLRLVKEDWERLCRRDPERTKFTWNNSSAMNAAFFDLCEVAKQMMIGLLNKETPSSAENHSFWILFAAHLNYACTTENGMPRDAVGMHKLNVKLKDFHFGGTRYLKDMPPEEQERRLERKKRIEEARRRGSSAHETHTDNWLLNDTFDYQQEDRKVEFEENGWMTPEAYVKHLGLKPCGDVTAAASPTEPIHVLVVLPRPAAAATAKDAKRDVPLATSEESIRLLMNPAAQRVLRGKARNVALPSPLSFGGVKITVLFDGDDIDCIHPDFVILQHLLATIEEDEAAKARVKYWARVARYCVFVVETDVRDRRHFLLREEVRVAYEDVAEDCFRSLHAAAYSTKYNRLRTTPSLIALCNRKNIGLRFKFRGSPLNTIALVVVGERLD
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Also specifically binds to base J-containing DNA (J-DNA).  Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis.  Thymine dioxygenase activity and J-DNA-binding are independent functions (By similarity).
What are the official names of this protein?
Thymine dioxygenase JBP1-A, J-binding protein 1A, Thymidine hydroxylase JBP1-A.
What is the protein family that this protein belongs to?
Belongs to the TET family. JBP1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTD_PSEF5
Sequence: MSTLYIAGQWLAGQGEAFTSVNPVTQAVIWSGNGATAAQVESAVQAARQAFPAWAKRSLEERISVLEAFAASLKSRADELARCIGEETGKPLWEAATEVTSMVNKIAISVQSYRERTGEKSGPLGDATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNSVLFKPSELTPKVAELTVQCWIEAGLPAGVLNLLQGARETGIALAANPGIDGLFFTGSSRTGNHLHQQFAGRPDKILALEMGGNNPLVVEQVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDTLLARLVAVSATIEVGAFDQQPAPFMGSVISLGAARALMDAQQQLLANGAVALLEMTQPQAQAALLTPGILDVSAVAERPDEELFGPLLQVIRYADFDDAIAEANNTQYGLAAGLLSDSAERYQQFWLESRAGIVNWNKQLTGAASSAPFGGVGASGNHRASAYYAADYCAYPVASLETPSLVLPSALTPGVRLS
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RRAAH_PSEPK
Sequence: MQHYVTPDLCDAYPDLVQVLEPMFSNFGGRDSFGGQIVTIKCFEDNSLVKEQVELDGKGKVLVVDGGGSLRRALLGDMLAEKAAKNGWEGLVIYGCVRDVDVLIQTDVGVQALASHPMKTDKRGIGDLNVVVTFAGVTFRPGEYVYADNNGVLVSPKPLKMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: PUR2_XANAC
Sequence: MKILVIGSGGREHALAWKIAQSARVSEVLVAPGNAGTATEAKCRNVAIKVDDLDGLLALAQREAVALTVVGPEVPLVLGVVDRFHAAGLRIFGPTAKAAQLEGSKAFAKDFLARHGIPTAYYAVHTEVDAALAYVREKGTPIVVKADGLAAGKGVIVALTLAEAEDAVRDMLSGNAFGDAGARVVIEEFLDGEEASFISMVDGKHALPMATSQDHKRVGDGDTGPNTGGMGAYSPAPVVTPEVHARVMREVVEPTVQGMIADGVPFTGFLYAGLMIDAHGAPKVIEFNVRFGDPETQPVMLRLQSDLVDLLEAAIDGKLDGAHAQWDPRPSLGVVIAARPYPDTPVTGEVIAGLDAVPASAKVFHAGTALNAAGEVVSAGGRVLCVAALGDSVQDAQRTAYAGLKPIHWSSAFQRSDIGWRAIARERQAQG
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: NODI_BRASS
Sequence: MNMSNMAIDLVGVRKSFGDKVIVNDLSFSVARGECFGLLGPNGAGKSTIARMLLGMIWPDRGKITVLDEPVPSRARARRGVGVVPQFDNLEPEFTVRENLLVFGRYFGMSARTIEAVVPSLLEFARLESKADVRVSLLGGGMKRRLTLARALINDPHLLVMDEPTTGLDPHARHLIWERLRALLARGKTILLTTHFMEEAERLCDPLCVLESGCKIAEGEPDALIDEHIGCNVIEIYGGDLDQLRELIRPYARHIEVSGETLFCYARCPDEISVHLRGRTGLRVLQRPPNLEDVFLRLTGREMEK
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit is responsible for energy coupling to the transport system.
What are the official names of this protein?
Nod factor export ATP-binding protein I, Nodulation ATP-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3.A.1.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPI1_CAEEL
Sequence: MRFILLIALVFAVLDGINCQIAGGLSDVNASEYTGAAWNSVPEINSKNNGQNYMVPIKVVKAQVQVVAGTNTVLEVLVGESTCPRQGSVQASQVTAANCPLKSGGKRELYKVSIWEKPWENFKQTKAEKIRGVKPDEKI
What is the function of this protein?
Cysteine protease inhibitor which inhibits members of the peptidase C1 family (PubMed:12704112, PubMed:15664654).  Does not inhibit asparaginyl endopeptidase (PubMed:15664654).  May play a protective role against exogenous cysteine proteases derived from soil bacteria or fungi, or rotting fruits and vegetation (PubMed:24001183).
What are the official names of this protein?
Cystatin cpi-1, Cysele1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
Protein: GAE6_ARATH
Sequence: MPLSATADTSKTVKLERYNSYLRKIHSTKVLNASSKVLFRATLLVALVLVLIFAINYPPLSDSRAAAAHHLHRRSFLSTGLFSSSSSSSSIGGAAWEKRVRQSSTAKRPHGLSVLVTGAAGFVGSHCSLALRKRGDGVLGFDNFNDYYDPSLKRARQELLEKQQVFIVEGDLNDGPLLRKLFDVVPFTHILHLAAQAGVRYAMKNPQSYIASNIAGFVNLLEVAKAANPQPAIVWASSSSVYGLNTENPFSEEHRTDQPASLYAATKKAGEEIAHTYNHIYGLSLTGLRFFTVYGPWGRPDMAYFFFTKDILHGKSIDIYRTQDNQEVARDFTYIDDIVKGCVGALDTAEKSTGSGGKKRGQAQLRVYNLGNTSPVPVGRLVSILEGLLGTKAKKHLIKMPRNGDVPYTHANVSLAYKDFGYKPTTDLAAGLRKFVKWYVGYYGIQPRVKKETSHAEDSA
What is the function of this protein?
Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.
What are the official names of this protein?
UDP-glucuronate 4-epimerase 6, UDP-glucuronic acid epimerase 6, AtUGlcAE2.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Protein: CA074_XENTR
Sequence: MASSLHKHLLSAARYHLKETKRMSMMVALNLAAEILAVDCGLKPCFLYDYTTSGVQQICSYLKELQNLGLIVGHLHILNIEETILIINVTKAVSYLETLLHSQDLHLIDVSNYLSQPELVSSNQVPQIHAQLAELLGHIKPYQSGQPASVSVGGIQSPEWNLCTMFGFFLQFPSTYWFDTQKGFENCLSFTPLRLFTVQANCSRIGHQSVQIYSFTVPECVYQATQVHLEDWSKSLKQAFNEQNYFTDLEIITNTVSLPSVAL
What are the official names of this protein?
UPF0739 protein C1orf74 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0739 family.
Protein: PEX5_CANGA
Sequence: MNMTDCSVGSNPLAQLNKHAQGQGSSLSNTHVRHSGGVSGSNVFRSGQNVVSEDGRQQLNSFMSQPMRLGEDKMHPATPMGSSMGNAIGGSMMQVDDSSMRSAGDSQWTREFRQNTAGKTNMAQEMGSSGAAMANSNAWKFRYSPMTNVNNTAPLRPFNNIIRQKERANGLETGDIAWNDKFDELEKEVSDKLNFKDGETVEKMDTGAEMQQDNLETGDSTDYQKEFQEVWDSIQQDTEEMLSYKDDYEDMLNDTDFERSFLGKRAVESLEYKFENPSENQYMNNPNAYQIGCILMENGAKLSEAALAFEAAIKQDPKHVDAWLKLGIVQIQNEKELNGMSALETCLKLDPNNLEAMKNLAISYINEGYDMSAYNMLNRWADTKYPGFYNSAELEGKRDEHENIHSKMTRRFLSLVNRINSVDPDIQLCLGLLFYANDEFDRTIDCFQAALKVNPNDELMWNRLGASLANSNRSEEAIQAYHRALQLKPSFVRARYNLAVSSMNIGCYKEAAEHLLTALSMHDVEGEFEVQSTRSNSISSADKYSFSGFKPTDNLLETLKRVFISMGRDDLLDRVRPGMDLSQFRNEFTF
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins.  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle.
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane (By similarity).
Protein: SYY_RICM5
Sequence: MRFIEEFINKGYFHQCTDLDRLTAITKETKIAAYIGFDCTATSLHIGSLMQIMILRLLQQHGHKPIVIIGGGTSKIGDPTWKDEVRKILSKEDIAKNAEGIKKSLSKFIKFGDGKSDAIMLDNAEWLDSFNYLDFLRDFGSYFSVNRMLTMDSVKLRLEREQHLSFLEFNYMLLQAYDFYYLSKHYNCSLQLGGSDQWGNIVMGADLIRKISGKEVFGMTTPLLTTSSGAKMGKTAAGAVWLNEDLLSPYDYYQYWRNCEDADIVRFAKLYSEFTQEELNRFEILAAEDINAAKKQLAYELTKLCHSEQAAKSALETAVKIFEEGQIDENLPTVVLEQEVLQAGISAYELFHEAGLATSKSEARKLIRGNGAKINDRLVEDENMIINTNFLLDKNVIKLSAGKKRHILVRV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_BURPS
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIQFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HBE_CEBKA
Sequence: MVHFTAEEKVAITSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MURB_PETMO
Sequence: MISEDLKLSLYAEGCDIKQNEFLKYYTSFRIGGPVPYILFPKTLNAFVNALSQLVKRDIPFRIIGQGTNLIISDEPLKFVVLSTKYLNKMNFEEKNNMDLIVEAQSGVSLSALSFLLSEDGYSGLEFACGIPGSVGGGVYMNAGAYGGEMKDVVLETTVYDLRDGKVKTLNKGDLEFGYRTSILQEGSFILLSTKFLLKKDELKRIKSKLIDFSTRRWEKQPIDLPSAGSIFKRPKPDFFVGTTIENLGLKGFSIGEAQISTKHAGFIINKGNATFKDVISLIEYVKRIVKDKYNVDLQVEPEIWK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRZJ
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RSMB_SALTY
Sequence: MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQHIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_RHOE4
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRKLLATGMERAGIAKVEIERTRDRVRVDIHTARPGIVIGRRGAEADRIRSELEKLTGKQVQLNILEVKNAEAEAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAANTAAPAGDRPRRERPSRPRRSGATGTTATSTEAGRAATATADAPATEQNQEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RRAAH_BURM7
Sequence: MMFATTDLCDAHEDRLAAGTLRVLEPVFRPFGGVRRFAGPAATLKLFEDNSLVRTALEQDGAGRVLVVDGGGSLRCALVGGNLGKLAEKNGWAGIVVNGCVRDSDELAECRVGVLALAAHPRKSDKRGAGVSDAPVDVRGTRIVPGDWIYADADGVLVSDDALLE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: MURA_NITOC
Sequence: MDKLLINGGISLNGEIRISGAKNAALPILAATLLASEPVKICNIPHLHDITTTMELLGRMGAQLMVDEHLNIEVDTRNLKEFYAPYELVKTMRASILVLGPLLARYGRADVSLPGGCAIGSRPVNLHIHGLQAMGATITVEEGYICARSQGRLRGTRLFMDRVSVTGTENLMMAATLAEGTTFIENAAREPEVVDLAHCLNQMGARISGMGSDTLVIEGVDSLGGASHTVLPDRIETGTYLVAGALTGGRVKLKNTSPGSLEAVLLKLEEAGAEINTGKDWIVLDMKGRRPRAVDIRTAPYPAFPTDMQAQFTTLNIVAEGSGTITETVFENRFMHVQELQRMGAVIRLEGNTAFTNGVETLTGAPVMATDLRASASLVLAGLVAKGVTAVDRIYHVDRGYECIEEKLQQLGAKIRRVSSYTPGKIYAAYG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTU2_DROME
Sequence: MAFNFGHLLIAGLVALSAVSSETIQLQPTQGILIPAPLAENIRVSRAAYGGYGAAPAAPSYSAPAAPAAQAYSAPAAPAYSAPAAPAYSAPAAPAYSAPAAPAYSAPAAPAYSAPASIPSPPCPKNYLFSCQPSLQPVPCSAPAQSYGSAGAYSQYVPQYAVPFVREL
What is the function of this protein?
Major early eggshell protein.
What are the official names of this protein?
Vitelline membrane protein Vm26Ab, Protein SV23, Protein TU-4.
What is the protein family that this protein belongs to?
Belongs to the vitelline membrane protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRC_BURCH
Sequence: MTSPEASATPFEPKKILAQLPHMPGVYRYYDTTGAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTAHRFPRMAYYRGSVDKQNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVGAISEEDYAVDVSNAARFLLGRQSEVMKELEQKMHAFAAELKFEQAAAVRNQMSSLATVLHQQAIEVGSDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPTHVESALTLAEGGLGEEVEPAEAVDATADAPVDTVPDQPAEEAGSARGAAAASVEAEVLDAFIAQHYLGNRVPPVLVVSHAPASRDLLELLSEQAGHKVSLVRQPQGQRRAWLSMAEQNARLALARLLSEQGSQQARTRALADTLSYDSDDLATLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQVLTRRYEKMVEQAAQAAAVDEAAGIDGESTRQAEASSLLPNIVLIDGGKGQVEIARQVFTELGLDTSMLVGVAKGEGRKVGLETLVFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKARQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVEELASVEGISHALAEQIYKQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y703_ACISJ
Sequence: MLKYAIIFAIISLIAGALGFTGVAAGSAAIAKVLFVVFLVLAVLFVVLALLGIGAARKAIK
What are the official names of this protein?
UPF0391 membrane protein Ajs_0703.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLP4_BETPN
Sequence: DFFFQGLNTPR
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved (By similarity).
What are the official names of this protein?
Germin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: U523A_DICDI
Sequence: MDKNNNNLNLNEVANSFIQFFNKKNYVDKEINSKIFNNTETDLWWITGDESIFPFSGWKPIQFRLNGMHFLNSGLDKYSMTETEKIIDNERRIILLVIKTLHMGYGMVNEYTAEIALVLSVNESGKIFSIKEYLDPSEIIRVANSTPALQELFKKVYGNFLN
What are the official names of this protein?
UPF0523 protein A.
What is the protein family that this protein belongs to?
Belongs to the UPF0523 family.
Protein: RDGC_NEIM0
Sequence: MWFKQISFYPLNKEKLPEADALADKLAEAEFTHCQGLDWFSEGFTAPVSFSPELVFPADFTLRVALKKEEKVLPAGVIRDILEEKVAEIQNNEARNVGRKEKQELKEQITDDLLPRAFTRSSRTEAVFNTRHGYLLVNNAASAKAENILTKLREALGGLEASLPNTKQSPSSLMTGWLLQGHCEGGFELDSDCELKGTGDIVPVVKVSKQDLTADEVVQHVKNGKTVTQLGLVWREQIAFILTQDFTLKRIQYLDVLQEEAESNGDDAAGLAFASQILMAESVSIMLEELVSYLGGWQD
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CLPX_SHESH
Sequence: MGDNKSNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPRELRAHLDDYVIGQDKAKKVLSVAVYNHYKRLKNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFVCGGAFSGLEKVIEQRSHTGTGIGFGAEVKGEDDKASISDILMQVEPEDLVKYGLIPEFIGRLPVLATLAELDDAALIQILSEPKNAITKQFAALFDMEGVELEFREDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTENVAKVVIDESVVKGESTPILIYENSESQAAGAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: FOXP2_MOUSE
Sequence: MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSEKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
What is the function of this protein?
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium.  May also play a role in developing neural, gastrointestinal and cardiovascular tissues.  Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential.  Plays a role in synapse formation by regulating SRPX2 levels.
What are the official names of this protein?
Forkhead box protein P2.
What are the subcellular locations of this protein?
Nucleus.