PharMolix/UniProtQA huggingface dataset:
Protein: SX18B_XENLA
Sequence: MHRSSYCREETTLCQGVNSTWVPPADTVPEASLTPHSPPAPDSPAPSPKPGYGYSACEEKPGDPRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGQSWKNLTSAEKRPFVEEAERLRVQHLQDHPNYKYRPRRKKQAKKLKRMDPSHHLRNEGYTGGQPMVNLSHFRELHPLGGSGELESYGLPTPEMSPLDVLEPSEPAFFPPHMREDPDPGLFRTYQHEMDFSQEKTLREISLPYSTSPSHMGSFLRTPTPSAFYYKPHGGSSARTPLGQLSPPPEAPALDAMDHLNHAELWGDFDLNEFDQYLNMSRTQGPGYSFPMSKLGGPRTIPCEENSLISALSDASTAMYYTPCITG
What is the function of this protein?
Transcription factor.  Binds to the consensus DNA sequence 5'-AACAAT-3'.  Also binds 5'-CACAAT-3' and 5'-AATAAT-3' but with a lower affinity.  Acts partially redundantly with sox7 during cardiogenesis, acting indirectly through nodal-signaling to induce mesodermal, organizer and endodermal tissues, which then interact to initiate cardiogenesis.  Also acts as an antagonist of beta-catenin signaling.
What are the official names of this protein?
Transcription factor Sox-18B, xSox18beta, SRY (sex determining region Y)-box 18B.
What are the subcellular locations of this protein?
Nucleus.
Protein: AHPC_STAA3
Sequence: MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CHEME
Sequence: MTNIRKTHPLMKIMNSSFIDLPAPSNISSWWNFGSLLGACLAIQIITGLFLAMHYTADTTTAFSSVTHICRDVNHGWIIRYIHANGASMFFLCLFIHVGRGMYYGSFTMLETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTVLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPLGISSDSDKIPFHPYYTMKDLLGLLFFLILHLTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVMALVLSILILTFIPMLQTTKQRSMLFRPLSQILFWILTADLFILTWIGAQQVEYPFITIGQMASILYFSIILIIMPTVSLMENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ORF3_PCV2
Sequence: MVTIPPLVSRWFPVCGFRVCKISSPFAFTTPRWPHNDVYIGLPITLLHFPAHFQKFSQPAEISDKRYRVLLCNGHQTPALQQGTHSSRQVTPLSLRSRSSTFNK
What is the function of this protein?
Plays a role in modulating host cell signaling by binding to and degrading host RGS16 (PubMed:25575706).  Not necessary for virus replication (PubMed:15956572).
What are the official names of this protein?
Protein ORF3.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Expressed in cytoplasm in early stages of PCV2 infection and then accumulated in nucleus over time.
Protein: YGMI_SCHPO
Sequence: MDFFWERMLNDPQNHFSDDQKEFLNHAKYRVKRNTIFGMLVGFSLPLYLARNKKVTPIRLYATSIIGGLAGNGVAQITTLAYNLSAIRQRDDGFEILRKIQDSLIRQRTTMRQGRFPSSSSEFPPKNSKYQLPGSMPNTGASSSQDPFTNSQSTEKEDAMYSKDNGFEDRSKPASAWEAIRNRNRNTGNNSFPFYEEDSSVKSTDSAFSGQENSEAFPSRTSNLGSEQLDEPISHEQEAFDQLIWNDSSSSK
What are the official names of this protein?
Uncharacterized protein C19G7.18c.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: RL25_PSEF5
Sequence: MNDFTLNAEVRSDLGKGASRRLRRLASLVPAVVYGGDKAPESISMLAKEVAKLLENEAAYSHIIELNVGGTKQNVVIKALQRHPAKGHVMHADFVRVVAGQKLTAIVPVHFINEAAPVKKGGEISHVIAEIEVSCLPKDLPEFIEVDLADAEIGTIVHLSDIKAPKGVEFVALAHGNDLAVANVHAPRVAPEAAEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TRMN6_PEDHD
Sequence: MKNAFRFKQFEIDQTGCAMRINTDGVLLGAVAGKNEAANILDIGTGTGVIALMLAQRFPNALVDAVEIDEQAALTATKNALNAPFSGRLKVLHSAIEDYLPEKYYDLIVSNPPYFVNDLKNPEHRKGVARHTDAHFFEQLLERVAAMLSRDGRFWFILPLKQAQNIVDMAKFYGLGMAVVLHIHSDENKPEIRQIVCLDYSGQPAHHHNLYIYAGKGLYTDAYKVLLKDFFLAF
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APRR6_ARATH
Sequence: MAGCLVPECADDISILLIDHDTASIASLTSMLQQFSKRVMSVDVASKALSMIEKQKKEIGLIIANIEMPHIDSHSFLNALLLKDIPLILINPEIKTKEPSDLLTKRACFSLDKPISNDDIKNMWQHVFSKKSQELKKINITEDQENVMDKDTYQIEAFRANLKRQRISQASLLGRRPFIDTFSTYETFQKRKSIANVEWKTTPSYAIEIENKRKEWKKSVGRRKSLWNSERHMKFIAAISILGEEDFRPKSILEIMNDPNLTHRQVGSHLQKYKAQIDQISYTLPRNESRSIDKTFEYPSNYKYPFKISDLTNNLIVSNSLWNSLEKKNSASASITQFLFKKPIGEKEETMPKFHIGGKLDLSNHSVHGNVLNKLSMNVNFVPSTISNNPAYNILSIDSSSIDSSSYTGLVSTGLSSENSPILYGLPSNDGASNTCTSQMESERISIPQYDPNQCHPHRSILETDVNQIDLDFTSILDSFDPLVDECLMKENNRFLPNPTMNLLDTDIDKMDWVSFIENLSHHDINMNHMDWDPSTANYVLPETNMNINFPEKHTNEIGWVSSQVGYVPFENMIPSEVDINHMGMGYSGGSIPPQEETNTNNVGFVSCEIHSEIPPKTNMAILETNYSNPLDWVFPEDITSLETNTIQKSLVSCETSYDALDNMVPLETNMEEMNDALYDISIEDLISFDIDANEKDIFSWLEDNGFSEENNMMESCEYHNIESVNQSDDMKIDDNFDDYRECMDWINEEMNKDV
What are the official names of this protein?
Putative two-component response regulator-like APRR6, Pseudo-response regulator 6.
What is the protein family that this protein belongs to?
Belongs to the ARR-like family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOIPB_ONCMY
Sequence: MSTTISTQRGQVYIGELPQDFLRITPPQQQQQVQLDAQAAQQLQYGESLGTVRRLSITVVQAKLAKNYGMTRMDPYCRVRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLEIFDERAFSMDDRIAWTHVTIPEGLREGSVVDEWYSLSGRQGDDKEGMINLVMSYANMTAGMHMSPPVVLMPTVYQQGVGYIPIAGVPTVYNQGMVPMGMPAAPTVAPQEAPCSEEDLKALQDMFPNLDREVIRTVIEAQQGNKDAAINTLLQMTEEL
What is the function of this protein?
Component of the signaling pathway of IL-1 and Toll-like receptors.  Inhibits cell activation by microbial products.  Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates.  The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).
What are the official names of this protein?
Toll-interacting protein B, Toll-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the tollip family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CS084_HUMAN
Sequence: MEQPKDGAGPEGNNLSLPSSGTEPWPPAPLPAPPPLLLNSTDPTHLGLPESVASVTVPIRLDTLSCLLHSALLGAYTFQQALPSCPCCSQAGHSQPGAVRRPPRGRGGWEVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQDGKKEARGPEPPLETPLAAEDWETEY
What are the official names of this protein?
Uncharacterized protein C19orf84.
Protein: CDT2_SCHPO
Sequence: MNMDIGKALSDVGGLRDITSRANNSLPPTPDSSPAAPSKKHKLYDFLESRGKIETPRKRIVFEKKPLLHKPVHIQKKPAQLCKELLIRQLGGSRSHPFSTKTSRHVGGRLNLETYYSRPSECLMMLNQLPFCLGFANNESLLAVCTETGALELFDSRFYDRQNEENQPSARRIHGWLAHNNAIFSVNFSKDDSLLATSSGDQTSKVFDLSTQQCITRLGRRGVDGYHSHSVKQVNFCNDSPYNLVSCSRDGSIIFWDMRTHGITIDGEHFQKPVLRIRKAHENSGRDCSITSATWLPQSTSQVISSCSANSALKLWDLRTVHTVRPLPAATTPELTTSKRDFGVTNVCTSPDGERIYAASRDSIIYEYSSRHLNSGFCKTYKDPRLRISSFYVKLACSPDGATLACGGGVQDKTSGVVVFDTTRNCSSSAMLTGGHTKDVTAVDWSSEGQLASISDDGSVRVWNSSLHGSAANLREKNFSEIFYWGFSEK
What is the function of this protein?
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for DNA replication during mitosis and meiosis.  The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of cdt1 and spd1.  Involved in the regulation of mitotic and pre-meiotic S-phase progression.
What are the official names of this protein?
Cell division cycle protein cdt2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat cdt2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYG_GRAGE
Sequence: MGLSDDEWHHVLGIWAKVEPDLSAHGQEVIIRLFQVHPETQERFAKFKNLKTIDELRSSEEVKKHGTTVLTALGRILKLKNNHEPELKPLAESHATKHKIPVKYLEFICEIIVKVIAEKHPSDFGADSQAAMRKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YBEY_STAHJ
Sequence: MFTIDFNDHTDLVNESWYHQIEDLLNFAKEQEQINEDAELSVTFVDKNEIQEINKTYRDKDKVTDVISFALEEDEPEIVGLDMPRVLGDIIICTNVAEEQADSFGHSFERELGFLALHGFLHLLGYDHMNEEDEKVMFSRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_MYCS5
Sequence: MQKDKKNYKLRKFGPITERRDYSITKHSLPVGDILATSKKSYQDFINKKIEELLNEIYPIEASNKEASLEYEKKSVKFELPFKKAEHENLQIKTCKAKKTNFSMKVYITLKKVVSQTGVVKKEKILLGEIPYITSSGSFIINGSEKVIVSQLIRSPGAYFGVSVRNKQSEDLFNKLEILPRIGSWIEVSHKVTSANLDAIKIKIDKNKNINIVTFLASFGLLADDIRYLFGKNEVLEETIRKNKTIDITEFSRQEIMDLCQEKIFRIIRKGDRISEESKRSLLSGMLFDKKRYNLSKTGRYMLNNKLSLVERITNTYLAQKVVSHLGNTFDVGTYVTYEIAKEIQESFEAKAKDNKSNLHLEKIPNINPDDVYYKINKDNKSLNKRINIARIKIWPTKRAMDANETPSEVIGNDPKATEEHLLLSDIIAAISYYLNLTVGIGQDDDPDSLMNKRIVSVGELLEGELRIALLKLEKATRERMGAKEPDKITAKNVTNNKLITNQMKTFFNTSKLAQFMDQINPLAEISNKRRVTSLGPGGLNRDTAQFEVRDVHSTHYGRICPIETPEGPNIGLILNYAIYSTVNELGFLQTPYYKVNDGVVDYNDVRYLTSYEEIGYAFAQSSVHVNDKNEIIDEQITIKKDYNYIIGSPKDIDFLEVSSKQIVSVAAAAIPFLENNDANRALMGSNMQRQAVPLIEAEAPLVATGIEADIAKFSSYNIVANNDGEVIYVDGTKIQVRTAKKIDTYNLKNFEKSNQGTIIQQKPIVKVGDHVKEGDLLVDGSSFKDGEMALGKNLLVGFTTWNGYNFEDAIIINERLVKDDVLTSIYIEEQTIQFRISKSSEDIMTRDIPNVSKYSMRNLDEFGIIKVGSEVVAGDVLVGRISPKGEENPSQEEKLLNAIFNQRPQNYKDTSLKVKNGHNGTVIHVEVLSRENGDILEDGLDSIIKVYIAQKRKIKVGDKMAGRHGNKGVISIILPEEDMPHLEDGTPLDIMLNPQGVPSRMNIGQVLEMHLGMAAKKLGTKFVTPSFDGIKKETIEDLLQEANLDKSGKQVVIDPITGEKFDNPISVGVIYMLKLNHMVDDKMHARSVGPYSLITQQPLGGKSQNGGQRFGEMETWALESYGASNILQEILTYKSDDIYSRNLVYKALVNDSAIPNPGMPESFNVLSNELKGLLMKLGITETESNSDELIQHFDHLGVEHE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL21_HALS3
Sequence: MPNSNGPLSNSGGKLQNDPRDRGTSPPQRAIADYDDGESVHLTLDPSVQDGRFHPRFSGLTGTVVGTQGDAFKVEVNDGGMDKTLIVGAAHLRTQRQEE
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: NANT_SALG2
Sequence: MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINILMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGB_PSYIN
Sequence: MTQALKPLLIKLGGAVLENEQALENLFSALTVYLQTEQRPLLIVHGGGVIVEDVLKKMNIVSYKKEGLRITPFEQIPYVAGALAGTSNKLLMAKALKAGLSAVGLSLADGFSCKVTQLDPDLGAVGICSPNNPALLNTLLKEGYLPVISSIAIGDDGRLYNVNADQAAITICELVGAELLFLSDVDGVWDAHKQVIPELNTQLADRLIAEKVIQDGMAVKVKAALQAAEQLGYVMLASWKNPENLVSLLAGQAVGTKVVK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLD_STAAC
Sequence: MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLITNTNVAPYSGVTWMGAGTGFVVGNQTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: INVO_MOUSE
Sequence: MSHQHTLPVTVPAVVQGPLKTVCSPDHIQQEQAKQPTPHPTQCQVFTEIQEKGFPKHEEKRPNPVKDLPDQKCEHQQQPGPQKQQLQVKKSQQELQEQELHLEKQQLPQEPQGLLCLEQQQQQEPQMQEQHLRQQQQQQQQQQQQQQQQQQQETQEQGLCLGQKQQQQQQDMLVPQELHLRQHQEKLQDPELHLGQQQKTPEEQKLIPGEKQQELHLGQRHQEPQEQELHLGQKQKQKLHEPELQLGKQQHQKPSEPELPLGKQQQESPEPELPLGKQQQQESPEPELQLGKQQQSHEPDMAGDQKEKQKLHKPELYLRKQQYQESPDPELSLGKQQHQECQEPELQLEEKQHQKPPEPELHLGKQQESHEPDMAEDLEEKQKLGEPELHLGKQQQQQIEREGYQGPKSLGQSLKQEKASREQQLDYSHLEQEKELSDQPLDQALVKKGKQLERKKHELENRTQQEK
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: PCDAD_HUMAN
Sequence: MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-13, PCDH-alpha-13.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RPOB_ECOLC
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: EX7L_ALKMQ
Sequence: MQIKALSVSEINHYIKRIMINDPILSNVYIKGEISNYKLHSSGHIYFTLKDEKSRVSSVMFKTNTEQLKFLPEEGMQVLCRGYISLYERGGLYQFYVDHMEAAGVGALYLAYQQLKEKLEKQGYFDGKFKKEIPLIPRKIAVVTSPTGAAVRDIISVIKRRFPHVEIYLFPVLVQGDRAAPSIARAVELLNLFGGIDVAIIGRGGGSIEELWPFNEETVAEAIFSSQVPIISAVGHETDFTIADFVADLRAPTPSVAAERVVPDVKEVVERLNTLKDRLNKTLVKSIDAKRNQLGIIKSNYYFKNPLNMIYDRQQHLDILMKDLTRNINVKNSLYSNNVHRLGERLNSVSPLSVFSRGYALAENKKGERIKTISNVKLKESITVQLIDGQLSCEVTNILKEDKLVGKNQI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTND1_XENLA
Sequence: MDEPESESPASILASVRAQEAQFELLSRALEEERRHVTAQLDRVWVTPQEPPLANGSLTRRQQDGLPFLYTPTRMEAHSVHADERYVIDDSSYKSCTLTDESRCSEIPIQTVVGYSQTLDRPYREAAGSGGAYTTVPRNYHFRGPGVDSTMPLISQSPHPGYSSLSRPNQRYRSVDPFRGPGYGPQPQVRGGGLGGSQSDLLSGRIYGSEDAYGLEDDRRSLGGFIDGPDYATTGRRGANGGDPRRRLRSYEDPLSDHFGSIPTSGSLSSLGPAPLTLAPNSGPWRHPELPEVLAMLSYTLDAVRLNAAAYLQHLSYRNEDVKREVCRLRGIPPLISLLEDPRAPIRLAACGALKNLSYGPARENKMAVKNCDGVPALARLLRRRGEGIEGRELAECVTGTLWNLSSLDSVKMELVDQALYTLTQEILVPHSGWQQDGGMQDRVEGKPRHVEWEPALVNTTGCLRNISSERSEARRKMRECEGLVDSVVHILRSEVSHGLVDSKLLENVVCLLRNISYHVHREIPHAEKYMESPQNASAETQNPSCFGVRRGKGKKASEEAVDTVDFPKQTMPAQGYDLLFQPEIVRLYISLVKSSHTPAVLEASAGAIQNLCAGNWVYGRCIRAAVRQEKGLSSLADHLTHESERVVRAICGALRNLCGDNRNRELIGKHALNSLVARLSSSSAQSSALSEDTNVCVINTIHEVISGNLEAAKRLRESQGIERLVLINKGGGRSEREIRAAGFCLQTIWGYKELRRPLEKDGWKKSDFQVSTAATSSVQGYDDSTLPLIDRNLKNEKKSVNADIPLNDFIADQFTHNGDSSNRLPTRSDELSELDPLKECSVSAGGSLNLGDAEDQRV
What is the function of this protein?
Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability.  Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics.  Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.  Required for gastrulation, axial elongation and development of the craniofacial skeleton and eye.
What are the official names of this protein?
Catenin delta-1, Xp120(ctn), p120 catenin, p120(ctn).
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm. Nucleus. Cell membrane.
Protein: CCHCR_GORGO
Sequence: MFPPSGSTGLIPPSHFQARPLSTLPRMAPTWLSDIPLVQPPGHQDVSERQLDTQRPQVTMWERDVSSDRQEPGRRGRSWGLEGSQALSQQAEVIARQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHKEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLQATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQVASLQEKVTSQSQEQAILQQSLQDKAAEVEVERMGAKGLQLELSRAQEARCRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGLIAQKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSVVSSPRPPECSASASVAAAVPTRESIKGSLSVLLDDLQGLSEAISKEEAVCQGDNLDRCSSSNPQMSS
What is the function of this protein?
May be a regulator of keratinocyte proliferation or differentiation.
What are the official names of this protein?
Coiled-coil alpha-helical rod protein 1, Alpha-helical coiled-coil rod protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVB_BACCZ
Sequence: MSIMDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFRGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.