PharMolix/UniProtQA huggingface dataset:
Protein: REC8_HUMAN
Sequence: MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLPNHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEIPPEVPTEPREPERIPVTVLPPEAITILEAEPIRMLEIEGERELPEVSRRELDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEVTPPEELRLPAPPSPERRPPVPPPPRRRRRRRLLFWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIRGPAELFRTPTLSGWLPPELLGLWTHCAQPPPKALRRELPEEAAAEEERRKIEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPALPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSSLVSPLSPRRMAARVFYLLLVLSAQQILHVKQEKPYGRLLIQPGPRFH
What is the function of this protein?
Required during meiosis for separation of sister chromatids and homologous chromosomes.  Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).
What are the official names of this protein?
Meiotic recombination protein REC8 homolog, Cohesin Rec8p.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II. Localized to centromeres and spindle poles in endopolyploid tumor cells.
Protein: PGK_MESH2
Sequence: MQPTYKNKKFIDDIDFLNKTVILRVDFNVPIKNGEISSIKRIIASLKTIKKIVNNGGKLVILSHLGRIKSKEDLPKKSLRIVAEKLAEILGQEIKFIPENRGPKVENAISQLEKGEILVLENTRFQDLNNKAESKNDAELGRYWASLGDVFINDAFGTLHRAHGSNVGIATYIKESAIGYLVKEELDALSKLIFSPQRPFYAIIGGAKISDKIGIISTLLEKADKVLIGGGMAYTFKKALGYKIGLSIYEDDKLELAASLVKKYPDKLILALDAALAPEFADLEPLYNQENPLEIPDHLEGMDIGPLTIELFKDHLKDGKTILWNGTLGVAEFKNFARGTKEVAKIIANLKECYSIIGGGDSIAAIEAEGLSNSFSHISTGGGASISFIENGDLIGLGPIQEKD
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_SODGM
Sequence: MRTVYCGQLNLSHVGQEVMLCGWVNRRRDLGGLIFIDMRDREGLVQVFFDPDRQDAFARAAELRNEFCLQLTGIVRARPDSQVNSEMATGAVEVLATELSIINCSEPLPLDSNQNNTEEQRLKFRYLDLRRPVMAQRLKTRARISSFVRRFMDAEGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTATQVREVMERLIRDLWREITGVDLGIFPQMTYADAMRRFGSDKPDLRNPMELVDVADLVKDVQFKVFSIPANDSQGRVAALRVPGGAQLSRKQIDEYGKYSEIYGAKGLAWMKVNQRAAGVEGVQSPVAKFLGPQVIEQILVRTGAADSDIIFFSADRKNVVTDALGALRLKLGLDLQLTVTDRWAPLWVVDFPMFEEDGEGGLAAMHHPFTAPKDVDAQMLAASPTSAVANAYDMVINGYEVGGGSVRIHRGDMQQTVFGILAINEQEQQEKFGFLLDALKYGTPPHAGLAFGLDRLVMLLTGTDNIRDVIAFPKTTAAADLMTEAPSFGNADALADLSIAVVGKGREAMENGRS
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM18_YEAS2
Sequence: MDRGRCANMLKSLQRTLAKCQKSPSTNHWQCFKRNFTSIRATKYPGRSNSTFHYWPWFAASTLLATSLYYRDRPVENDDKTDAFPSHTESIQVDSSVSDFPLTITALNFPVSTTFKLLGYGQRHVTFLRFKVYALGLYLAENDENLVSDTLNETYLRKYFLDVDDSKTPKENLARLLKRDDSKSVMMIDDLLDSGMRMLAKITPVRNTDFKHLKEGLVKTISKHPDVANNKDTLAKGLSELNDAFSRKGSVRKNDDLIIELLANGALQFSYHDSKNNEFEVMGVVNNQLVGKFLFSQYLCGEKSPSPQAKKTAIDKLITLL
What are the official names of this protein?
Altered inheritance of mitochondria protein 18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM18/AIM46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ENO_ACTP2
Sequence: MAKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVSAVNNEIAQAILGKDGSAQAEIDQIMIDLDGTDNKSKFGANAILAVSLATAKAAAASKGLPLYAYIAELNGTPGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGASTLKEALRIGAEVFHNLAKVLKSKGLNTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKDVTLAMDCASSEFYNKENGLYEMKGEGKSFTSQEFTHYLEGLCNEYPIKSIEDGQDESDWEGFAYQTKVLGGKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALAAAGTPAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL18_PSEF5
Sequence: MTDKKVTRLRRARKARLKMHELEVVRLCVFRSSQHIYAQVISADGNKVLASASTLDKELRDGATGNIDAATKVGQLVATRAKAAGVSQVAFDRSGFKYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FER_TRIVA
Sequence: MLSQVCRFGTITAVKGGVKKQLKFEDDQTLFTVLTEAGLMSADDTCQGNKACGKCICKHVSGKVAAEDDEKEFLEDQPANARLACAITLSGENDGAVFEL
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.  It links pyruvate:ferredoxin oxidoreductase to hydrogenase.
What are the official names of this protein?
Ferredoxin.
What are the subcellular locations of this protein?
Hydrogenosome.
Protein: SCP27_ARATH
Sequence: MDYSFLLIILLLTISTSCCAAPSSYVEEQLRDRISNLPGQPSNVDFRQYSGYVTVHEERGRALFYWLVESPLARDPKSRPLVLWLNGGPGCSSVAYGAAEEIGPFRVGSDGKTLHSKLYAWNKLANLLFLESPAGVGFSYSNTTSDLYTTGDQRTAEDSYIFLVNWFERFPQYKHREFYIVGESYAGHFVPQLSKLVHERNKGFKNPAINLKGFMVGNAVTDDYHDYIGTFEYWWNHGLISDSTYHQLKTACYSVSSQHPSMQCMVALRNAELEQGNIDPYSIFTKPCNSTVALKRFLKGRYPWMSRAYDPCTERYSNVYFNRLDVQKALHANVTRLSYPWKACSDIVGSYWDDSPLSMLPIYKELITAGLKIWVFSGDTDAVVPITATRYSVDALKLATITNWYPWYDHGKVGGWSQVYKGLTLVTVAGAGHEVPLHRPRQAFILFRSFLESKPMPMT
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 27.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTND_PROM3
Sequence: MSRLSIHPEGNTNATSPAEPLLESDDPAVIKAELAKRGIEFQHWPAKVKLHQNSIESDILAAYAVEIARVQADGRYPTVDAIRITPDHPDREALRQKFLAEHTHAEDEVRFFVEGRGLFCLHIGAEVLQVLCEQNDCINVPAGTRHWFDMGSKPQFCAVRFFDNPEGWIASFTGDAIAERFAKLP
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: DAPE_XANC8
Sequence: MTSDVLQLTCDLIARASVTPADAGCQALIADRLSAAGFACEHLRLGAVDNLWATHGSGAPVLVLLGHTDVVPPGPASDWASDPFAPQVRDGVLYGRGAADMKGSVAAFVVAAEQFVAAHPEHPGTLAVLLTSDEEGDAIDGVRHVARLFAERGQQIDWCITGEPSSTERLGDLLRVGRRGSLSGNLIVKGVQGHVAYPHKARNPIHLAAPALAELIARQWDDGFESFPPTSLQISNIHAGTGANNVIPGELQVAFNLRYTPHWNAETLEREIVALLERHALTYTLAWHRSGEPFYTPEGTLRRVAREVLGAFVGAPPEESTGGGTSDARFIAPLGAQCIEVGPVNASIHQVDEHVRVADLEALPALYRTLVERLLV
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CMR1_PICST
Sequence: MAKISEFERQRQENIQRNKELLKSLNLDSLSQSIKRELPRASETKKRKTTPRTKAVKKEDVEPSRRSRRIAGIKSELENPEEYNHKKSGSLKFEDKVIKSDSTEPEVKQEEKEELSEDIKNDNKVLHRLQALGDKFSAGDFFDIIQKNPIQYDDKVLQSTRDEFDKLKIYEKHNPLDIKISHTRITAINFHPSTTDRVVAAGDTNGNVGIWAVDSGEDDSEPTISILRPHGKAISRILTPVAEQNKLYSASYDGSVRVLDLNKLASTEVVYLNDPYENDDYALGVSDINFCASDANLLYMTTLSGSFHKHDIRTPFKPLKSKDILRLHDKKIGSFSINPNNTYQIATASLDRTLRIWDLRNVSKANAEWSEFENQISPHLYGSFSSRLSVSCVDWNSENRLVCNGYDDYINIFDLNEESLIPDNLKAFNKIKHNCQTGRWVSILKSKWQVAPEDGVQKFVIANMNRALDIYDQKGQIIAHLTDSVGAVPAVCGFHPTKNWVVGGSASGKVYLFE
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: CBSA_SULAC
Sequence: MSLKIKSKITIGVLLIIFLLSIIFTLENVSLAQTSPQISVYKVVGSADLSNPGSAGYWSQIPWTNISLTANIPMAPTSGLTHYLLVKAAWNGSWIFILEEWQAPEPAFNAWSTAVAGIYPNASGPGLFRMIELTPGTTYSLERNYTNYVSIINGKEETGRIVFNYSGITLPAPNNTEITVMSNGTILLWHSPRPVEDLLYNDGMFYGYYVNSTWYYPDRAAIMWYLGSGVPTKDDMNIGGKYPGQQFDGITFKDAGGSLAQSGGSANIWMWVSGATWNNSTYDPAFKSNIWQNESLTGLSYVDSGNHGFAVPLYTNNTNMYEVDTAGIWYTPVASEGLNGSLFFIWTGAKYENGSWVVEFARPLSVPLDYQPFMPNITVGKTYYVAFAVWQGRLGETLFDKSITSSFLSLELVTTPPTSTTTSTSPVTTISSAIPPVTLYVTIIGVVVALVALVILYVVFRR
What is the function of this protein?
Monoheme cytochrome whose physiological function is not yet clear.
What are the official names of this protein?
Cytochrome b558/566 subunit A.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GTX3B_NEOGO
Sequence: GWKDWLKKGKEWLKAKGPGIVKAALQAATQ
What is the function of this protein?
Shows a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.  Has also antimicrobial activity against S. cerevisiae.  Has insecticidal and non-hemolytic activity.
What are the official names of this protein?
U1-poneritoxin-Ng3b, U1-PONTX-Ng3b, Poneratoxin, Ponericin-G2.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAA7E_RAT
Sequence: MATDDASFPWDQDSILSRDLLSALSSQLCYENLNRSCIRSPYSPGPRLILHAVFGFSAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADLLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDVSFCYSSIFHLCFISVDRYIAVSDPLIYLTRFTASVSGKCITFSWFLSIIYSFSLLYTGASEAGLEDLVSALTCVGGCQLAVNQSWVFINFLLFLVPTLVMMTVYSKVFLIAKQQAQNIEKIGKQTARASESYKDRVAKRERKAAKTLGITVAAFLLSWLPYFIDSIIDAFLGFITPTYVYEILVWIAYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 7e, TaR-7e, Trace amine receptor 7e, Trace amine receptor 14, TaR-14.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CIS3_YEAS6
Sequence: MQFKNVALAASVAALSATASAEGYTPGEPWSTLTPTGSISCGAAEYTTTFGIAVQAITSSKAKRDVISQIGDGQVQATSAAATDSQVQASSTATPTSSEKISSSASKTSSTNATSSSCATPSLKDSSCKNSGTLELTLKDGVLTDAKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITEDGYLALGDSDVFYQCLSGNFYNLYDQNVAEQCSAIHLEAVSLVDC
What is the function of this protein?
Component of the outer cell wall layer.  Required for stability of the cell wall and for optimal growth.  Required for resistance against several antifungal and cell wall-perturbing agents (By similarity).
What are the official names of this protein?
Cell wall mannoprotein CIS3, Covalently-linked cell wall protein 5/11, Protein with internal repeats 4, Soluble cell wall protein 8.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently attached to the cell wall. Localizes predominantly on the surface of growing buds (By similarity).
Protein: AMYG_CANAL
Sequence: MKLLSKVFVTALGLTSIVNAAPTSSSSAEEAQKTVPVELSIGVKQLPNIHNDSAVDANAVAKGYSLVNVSLTARGLTGILKLKEATNIYGYDFEYLNLSVEYQSDTRLNVHIEPTDLTDVFVLPEELVVKPKLEGDAKTFNFENSDLVFEYDEEDFGFEVLRSSTREVLFSTKGNPLVFSNQFIQFNTTLPKGHSITGLGESIHGSLNEPGVVKTLYANDIADPIDGNIYGVHPVYYDQRYNTNTTHAVYWRTSAIQEVVVGETSLTWRALSGVIDLYFFSGPDPKDVIQQYVSEIGLPAMQPYWALGYHQCRWGYDTVESLETVVENFKKFDIPLETIWSDIDYMDGYKDFTNDPYRFPTDKFRKFLDDLHNNSQHYVPIFDAAIYVPNPNNATDNDYEPFHLGNESDVFLKNPDGSLYIGAVWPGYTVFPDFLANNTQEYWNKMFKDWYERIPFDGIWTDMNEVSSFCVGSCGTGRYFDNPVHPPFEVGYSGSDYPLGFDKSNASEWKSISEAAAATKTTTTTSSSTSTSIDGKNTLAPGKGNINYPPYAINNNQGDHDLATHAISPNATHADGTVEYDIHNIYGLIQERAIYEALLEIHPNKRPFIIGRSSFAGSGKYMGHWGGDNYADYYMMYFSIPQALSMGLSGIPFFGVDACGFNGNTDMELCSRWMQLASFFPFYRNHNVLGAIPQEPYVWEGVMNATKTSINVRYSLLPYYYTLLHESHVTGIPIMRAFNWQFPYSKELAGVDTQFFVGDALLVTPVLEPGVNHTKGVFPGENAVYYDFYTHKKQKFTAGKNETLAAPLGHIPLHIKGGNIIPTQEPGYTTTESRKNPFGLLVALDAEGTASGKLYLDDGESVDVEEALYVDFVASKNKLVASVFGEYEVRQPLANVTILGVDSEPKKVLFNNETVSHNYENGAVYLTDLEKFTKEGAFAEEFSIQW
What are the official names of this protein?
Glucoamylase 1, 1,4-alpha-D-glucan glucohydrolase, Glucan 1,4-alpha-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: MOAC_SODGM
Sequence: MSQLTHITERGEAHMVDASAKADTVREARASAYVTMARATLAMILDGQHHKGDVFATARIAGIQAAKRTWELIPLCHPLMLSKVEVQLTAETEQHWVRIDAVCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMFIGPVRLLAKSGGKSGDFTGDEV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: HIS6_BRUMB
Sequence: MTLKARVIPCLDVKDGRVVKGVNFVDLIDAGDPVEAARAYDAAGADELCFLDITASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVADIRKLLLAGADKVSINTAAVKNPEFVAEAADKFGNQCIVVAIDAKKVSGAGENDHWEIFTHGGRQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGTKAGYDVALTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEAKRYMAEAGIPMRLDPVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMF_ECO5E
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLRLTAPYGWTLTPIPWCEEGFWIERDDEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRSGGTLVYSTCTLNREENESVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPTPKYKVGNFPFSPVKDREAAQIRQAAASVGLNWDGNLRLWQRDKEVWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNENAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMB_MACLB
Sequence: DQDCLPGWSFYEGHCYKVFDVKKTWEDAEKFCTEQMSGGHLVSFHSSEEVDFMIKLASPILKFDLVWIGLSNFWRDCHWGWSDGVKLDYKAWSDKPNCYVAKTVDPQWLHRDCSRTYKFVCKSRVPR
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec macrovipecetin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROC2_BACCR
Sequence: MRYITAGESHGPQLTVILEGVPAGLTLTAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKDMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILSELGVEIAGHVLEIGGVKAKHISNLSIEEIQTITENSPVRCLDKEVEQEMMNAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEEKGYTRRTNNAGGLEGGMTTGMPIIVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELADALVEQFGKDRMELLKQNIMQHNNYAKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 2, CS 2, 5-enolpyruvylshikimate-3-phosphate phospholyase 2.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TRPA_LEPBA
Sequence: MSKIKELFESGKFKSAFIPYFTLGDPNYNDSIEFGKTILDGGADILELGIPFSDPVADGPVIQRAVARSLKNKFSFDEIFRVTKQIHLHKQETPLVYLTYFNPIYHCGITKFLDNAKDSGVVGLVIPDLPFDTIESETLFQELRLRDMDLIHLVTPASTKKRIEALRKTSTGFIYYVTSFGVTGERREFSVDLKERIRFLKDTIQLPICAGFGISTPEQASQIAGYADGIIIGSAIQRVIEENGQDASKAKNVLADYITKIRASIS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: KYNB_CUPMC
Sequence: MPQAPQLHDGRRIWDISPAVSPATPVWPGDTPFQHDPAWQLDEHCPVNVGRITMSPHTGAHADAPLHYAADGAPIGAVPLDAYLGPCRVIHCIGAAPRVEPQHIAHALAGTPPRVLLRTYAQAPQGKWDSAFCAVAPETISLLARHGVRLIGIDTPSLDPETSKTMDAHHAVRDHQLAILEGIVLDEVPAGDYELIALPLRLATLDASPVRAVLRELP
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: SYQ_SALPB
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSDYFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKLEMGSREVPFSGEIWIDRADFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPSLKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L2HDH_CAEBR
Sequence: MLTRKTFHAFRSISGPPKKSVELPKYDLVIVGGGIVGCATARQLLIEKPNLKIALVEKEKELAVHQSGHNSGVIHAGIYYTPGSLKAKLCVEGLDLSYEFFDKEKIPYKKTGKLIVAVEQEEVPRLDALFARAQTNGCRDIEMIDSKRITDIEPHCKGLKALWSPHTGIVDWGYVTKKFGEDFEKRGGKIYTSYPLEKIEDNLKDSNYPIRVSSDPSYADFETKNLITCAGLQSDRVAALSGCSTDPKIVPFRGEYLLLKPEKRHLVKTNIYPVPDPRFPFLGVHFTPRMNGDIWLGPNAVLAYKREGYSYFSISPSDLLESLSYSGMQKLVKKHFTFGIKELYRGIWIAAQVKQLQRFIPELKYSDVTRGPSGVRAQAMDSAGNLVDDFVFDSGTGKLSSLIMHVRNAPSPAATSSLAIAKMITSEAITRFKL
What are the official names of this protein?
L-2-hydroxyglutarate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the L2HGDH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PRS8_XENLA
Sequence: MEQMEMDESRGGTGLRQYYLSKIEDLQLVVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPEHFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWKCFFLVPILCSTVCFQLKPSDVYYMGAWLIKPTRFNRRIITNSYHLQIFKPTIVLANGECHN
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity).  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 8, 26S proteasome AAA-ATPase subunit RPT6, Proteasome 26S subunit ATPase 5, SUG1 homolog, xSUG1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL25_SALCH
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: MTNB_XANOR
Sequence: MNATTAPLPYSAARLHELAHVLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGLAVGRPLRPSAETLLHTQLYRRFPEICCVLHTHSPVQTIASRLYAGSDVIRLEGYELLKAFEGNTTHETAVEVPVFANTQDMQVLAAQVDALLDKQSVWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLQCELELLKLRGTRQVVPVPHS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.