PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_GRAFK
Sequence: MAILNFQKPDKVIMIDSTDFEGKFEFRPLEPGYGLTVGNALRRVLLSSLEGFAITSVRIEGVDHEFSTIAGVVEDVTEIILNLKQVRFKRQIDEIDNESVTISVSGEEQLTAGHFQKFISGFQVLNPDQVICHMDKKVSLNMEITIEKGRGYVPAEENKKANAPLGTIFVDSIYTPIKNVKYSIENFRVEQKTDYEKLVFEIISDGSIHPKDALTEAAKTLIHHFMLFSDERITLEADEIAQTETYDEESLHMRQLLKTKLVDMDLSVRALNCLKAAEVDTLGDLVSYNKNDLMKFRNFGKKSLTELEELVSNKGLNFGMDLSKYKLDKD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: KAD_CALS4
Sequence: MRVVLLGPPGAGKGTQALKIAKEFDIPHISTGDIFRQNLRDNTELGKLAKEYMDKGLLVPDEVTNRIVEDRLEKEDCKKGFLLDGYPRNIPQAEELDKFLEERGHSLTAVINIQVEREALIDRITGRRVCPVCGATYHIKTSPPKVDNVCDKCGSELIQRSDDKLESVVKRLEVYEKETKPLIDYYTKKGILVNIDGNKSIDEVFEDIKKALLGDRRDDIH
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBCW_ECOLI
Sequence: MNKEQSADDPSVDLIRVKNMLNSTISMSYPDVVIACIEHKVSLEAFRAIEAALVKHDNNMKDYSLVVD
What are the official names of this protein?
Uncharacterized protein YbcW.
Protein: YHAM_GEOKA
Sequence: MAKGIIHYEVGEQVDLFLLIKSATKGIASNGKPFLTLILQDKSGDIEAKLWDVSPDDEERYVPECIVKVAGDIHNYRGKLQLRIRSIRPAHPGDAVRIDDFLEKAPLGREEMKAKVMEYIFAMENPNIQRITRYLLKKYEKAFFEYPAATKNHHEFISGLAYHVVSMLELAKALIHLYPSLNKDLLYAGVILHDLGKVIELSGPVSAAYTLEGNLLGHISIMVSEISKAAEQLGIQGEEVVILQHLVLAHHGKAEWGSPKPPLVKEAEVLHYIDNLDAKITMIDRALEKVKPGEFTERVFALDNRSFYKPAFLSVSKPKNPGSKE
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: FPG_POLNA
Sequence: MPELPEVEVTRLSFAERIAGARIEAVLVGKPLRWPLGCETQQLQGQRVLAVRRRGKYLLLDLSEGLLLMHLGMSGSVSFGLNLPVTGKHDHFDMVTSLGTLRLHDPRRFGAVVYASGEDDAVAKKLLGRLGVEPLSDAFDALVFHQWLKGRKTAIKPLLLAGQAVVGVGNIYASEALFLAGIRPTTKASLISKPRAARLHRAIQDVLTNAVAKGGSTLRDFSNADGEAGHFQLDAMVYDRAGLPCRVCAAPIKSIRQGQRSSFYCATCQKP
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RBFA_PARPJ
Sequence: MPKKRSSPNRNVQIADQIQRDLSDLLREVKDPRIGIVTIQSVELTPDYAHAKVYFTTLTGDPQQTLEALTHAAGHLHNQLFKRLHIHTVPTLHFHYDKTIERAVEMSRLIDEANANRAKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP9_USTMA
Sequence: MLAAAKYIGSGVAALGLIGAGIGVGIVFAALIQGVSRNPSLRGQLFTYAILGFALSEATGLFALMVSFLLLYS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COAD_MICLC
Sequence: MRRAVCPGSFDPLHKGHVEVIARAANLFEEVVVAVSANPAKTYRFSVDERIAMIEATVSSLAGVAVRPMGPGLLAEFCRQIGADAIVKGLRGGADLEFEAPMAAMNRHLTGVETVYLPADARYTHVSSSLIKEVHGLGGDVAEFVPAAVLRGLDGGA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX3_HUMAN
Sequence: MAAMETETAPLTLESLPTDPLLLILSFLDYRDLINCCYVSRRLSQLSSHDPLWRRHCKKYWLISEEEKTQKNQCWKSLFIDTYSDVGRYIDHYAAIKKAWDDLKKYLEPRCPRMVLSLKEGAREEDLDAVEAQIGCKLPDDYRCSYRIHNGQKLVVPGLLGSMALSNHYRSEDLLDVDTAAGGFQQRQGLKYCLPLTFCIHTGLSQYIAVEAAEGRNKNEVFYQCPDQMARNPAAIDMFIIGATFTDWFTSYVKNVVSGGFPIIRDQIFRYVHDPECVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGRVYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPTFRVSIARLEMGPDEYEEMEEEEEEEEEEDEDDDSADMDESDEDDEEERRRRVFDVPIRRRRCSRLF
What is the function of this protein?
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, SCF(FBXO3), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:18809579, PubMed:26037928).  Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome (PubMed:18809579).  In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented (PubMed:18809579).  PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation (PubMed:18809579).  The SCF(FBXO3) also acts as a regulator of inflammation by mediating ubiquitination and degradation of FBXL2 in response to lipopolysaccharide (LPS) (PubMed:26037928).  The SCF(FBXO3) complex specifically recognizes FBXL2 phosphorylated at 'Thr-404' and promotes its ubiquitination (By similarity).
What are the official names of this protein?
F-box only protein 3.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PML at the peripheries of nuclear bodies.
Protein: CIB2_HUMAN
Sequence: MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHSRFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVAAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEEEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
What is the function of this protein?
Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity).  Acts as a auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (By similarity).  Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing (By similarity).  Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells (By similarity).  Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea (By similarity).  Critical for proper photoreceptor cell maintenance and function (By similarity).  Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970, PubMed:26426422).
What are the official names of this protein?
Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Note=Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (By similarity). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (PubMed:26173970, PubMed:26426422).
Protein: TATA_CAUVC
Sequence: MGSMSWIHWVIVLGIVALLFGGRGKLSSIMGDAAKGIKAFKDGLKDESSSEVADNKAKSALPRTEAEAEELRKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y1435_CLOAB
Sequence: MKLMRKNETREFLIEDIEFPAVGVAFYNDKKVYIKGAVPGQKVLARVSKVRREKIEAKLKEIVTNIPGAAQPKCPDFGVCGGCVHQFLPYEKQLEFKEREVLKLFKDAKIEGFEYLGILGSPEKEEYRNKMEYTFGDFVKGGELTLGMHAKNSGFSIVNTDKCNIVDEDFRIILKTVVEYFRKKDLPIYKVMQHVGYLRNLVVRKAKNTGEILIALVTTSQVDFDLTELTEILKSINYLGELKGILHVINDGLADMVRGDKIVTLFGQDYITERILDLKFKISLFSFFQTNSKGAEKLYSEVLEFLGDVSNKTVFDLYCGTGTIGQLASKKAEKVIGIELIEEAVEAAKENTKLNNISNCSFIAGDVAKVITEIKEKPDTIILDPPRPGVSPNAMKYVIKFNAPEIVYVSCNPKTLVNDLGVLRAYGYEVEKVKIVDMFPGTGHVETVVLLQRKII
What are the official names of this protein?
Uncharacterized RNA methyltransferase CA_C1435.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: DNAK_STRS7
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAEDYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFDDLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQAALDELKKAQESGDLDDMKAKLEALNEKAQALAVKMYEQAAAAQQAQAQAGAEGAADTGSTNSGDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NCPR_ASPOR
Sequence: MAQLDTLDLVVLVALLVGSVAYFTKGTYWAVAKDPYASSGPAMNGAAKAGKTRDILEKMEETGKNCVIFYGSQTGTAEDYASRLAKEGSQRFGLKTMVADLEDYDYENLDKFPEDKVAFFVLATYGEGEPTDNAVEFYQFITGEDVAFESGASAEEKPLSALKYVTFGLGNNTYEHYNAMVRNLDAALQKLGAQRIGSAGEGDDGAGTMEEDFLAWKEPMWTALSEAMGLQEREAVYEPVFNVTEDESKSAEDETVYLGEPTKGHLEGQPKGPFSAHNPFIAPIVESRELFTVKDRNCLHMEISIAGSNLTYQTGDHIAVWPTNAGAEVDRFLQVFGLEEKRHSVINIKGIDVTAKVPIPTPTTYDAAVRYYMEVCAPVSRQFVSSLAAFAPDEATKTEIQRLGSDKDYFHEKITNQCFNIAQALQSITSKPFSAVPFSLLIEGLNKLQPRYYSISSSSLVQKDKISITAVVESVRLPGASHLVKGVTTNYLLALKQKQNGEPSPDPHGLTYAITGPRNKYDGIHVPVHVRHSNFKLPSDPSRPIIMVGPGTGVAPFRGFIQERAALAAKGEKVGTTVLFFGCRNRNEDFLYQDEFKAYEEQLGDSLKIITAFSRETSQKVYVQHRLREQAELVSDLLKQKATFYVCGDAANMAREVNLVLGQIIAQQRGLPAEKGEEMVKHMRSSGSYQEDVWS
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.  Involved in ergosterol biosynthesis.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Single-pass membrane protein; Cytoplasmic side. Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: AROE_METPP
Sequence: MKDRADAAARDRYAVAGHPVEHSRSPFIHARFAALTGEPIDYGRLPCPLDGFAATVSAFAASTGTGLGPARGCNVTVPFKFEAVALAAQLTPRAALAQAANTLRFDAEGWQADNTDGAGLVRDITVHAGVALQGATLLLVGAGGAAAGVLGPLLETGPQRLVLANRSPDRARTLVERHAALAALHGVTLEAAALDDCGDGYDIVVNATAASLAGATVPVTARVLRPGALALDMMYGPAAQGFLRWAAAHGAHGRDGLGMLVEQAAESFWFWRGVRPPTPAVLAELRAVIEGADT
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: STK4_OTOGA
Sequence: METVQLRNPPRRQLKKLDEDSLTKQPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVRQCLVKSPDQRATATQLLQHPFVKSAKGVSILRDLINEAMDVKLKRQEAQQREVDQDDEENSEEDELDSGTMVRAVGDEMGTVRVASTMSDGANTMIEHDDTLPSQLGTMVINADDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSDWKVPQDGDYEFLKSWTVEDLQKRLLALDPMMEQEIEEIRQKYQSKRQPILDAIEAKKRRQQNF
What is the function of this protein?
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.  Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.  Phosphorylates 'Ser-14' of histone H2B (H2BS14ph) during apoptosis.  Phosphorylates FOXO3 upon oxidative stress, which results in its nuclear translocation and cell death initiation.  Phosphorylates MOBKL1A, MOBKL1B and RASSF2.  Phosphorylates TNNI3 (cardiac Tn-I) and alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).  Phosphorylates FOXO1 on 'Ser-212' and regulates its activation and stimulates transcription of PMAIP1 in a FOXO1-dependent manner.  Phosphorylates SIRT1 and inhibits SIRT1-mediated p53/TP53 deacetylation, thereby promoting p53/TP53 dependent transcription and apoptosis upon DNA damage.  Acts as an inhibitor of PKB/AKT1.  Phosphorylates AR on 'Ser-650' and suppresses its activity by intersecting with PKB/AKT1 signaling and antagonizing formation of AR-chromatin complexes.
What are the official names of this protein?
Serine/threonine-protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The caspase-cleaved form cycles between the nucleus and cytoplasm.
Protein: TRUA_POLSJ
Sequence: MRIALGISYSGSAYEGWQSQLSGNTVQDKLESALARFAAQPVRTLCAGRTDAGVHGLMQVVHFDTVLHRDMGSWVRGTNAFLPSDIAVQWAREVPDTFHCRGSAIARRYAYVVLESPVRPSVEAGRVGWVYRPLDGAAMRQAITHLVGEHDFSSFRAAQCQAKSPVKTINRIEISERAGTGSKYWHFEFEANAFLHHMIRNIMGCLVAIGQGSHEPGWLLDVMAARSRDAAAPTFSPNGLYFLGPVYEDHYGLPNRTAAYDWLP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: UREF_PSE14
Sequence: MNSAWALLRLASPQLPIGGYSYSQGLEMAVEQSIVVDPQTAGRWISDQLLLNLARFEAPLLLAHCEAASAGDWGQLLQVSEQHRASRETRELHQESRQMGYSLQQLLNGLPELDRDARHFLEQTAEPHLALGWALAARAWQISPQDALAAWLWSWLENQLAVLMKTLPLGQQAAQRLTSELLPLLQQAQVNATRQDTHHAGSAAFGLSLASMAHERQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_THEP1
Sequence: MKVLPAKKVEGVLSVPPDKSITHRALILSALAETESTLYNLLRCLDTERTHDILEKLGTRFEGDWEKMKVFPKPFAEPIEPLFCGNSGTTTRLMSGVLASYEMFTVLYGDSSLSRRPMRRVIEPLEMMGARFMARQNNYLPMAIKGNHLSGISYKTPVASAQVKSAVLLAGLRASGRTIVIEPAKSRDHTERMLKNLGVPVEVEGTRVVLEPATFRGFTMKVPGDISSAAFFVVLGAIHPNARITVTDVGLNPTRTGLLEVMKLMGANLEWEITEENLEPIGTVRVETSPNLKGVVVPEHLVPLMIDELPLVALLGVFAEGETVVRNAEELRKKESDRIRVLVENFKRLGVEIEEFKDGFKIVGKQSIKGGSVDPEGDHRMAMLFSIAGLVSEEGVDVKDHECVAVSFPNFYELLERVVIS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_ASPFU
Sequence: MAQEIEKTNNDHLVQSSDPEHPANLIPELCRKFYNWGWVTGTGGGTSIRRGDHIFIAPSGVQKELIQPHNIFVLEFPTPKYPPSDRKYIRKPLELKPSACTPLFLTAFERGAGCCIHTHSQWAVLVTLLVEREKGPDACFEISNIEQIKGIPRGKGKGMLGFFDTLRIPIIENTAFEEDLTESLEKAMDQYPDTYAVLVRRHGIYVWGDDVAKAKTQCESLDYLFQLAVEMHKLGLPWVK
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXZ_RUEPO
Sequence: MALNGPQKTVVQLVSVVVVMGGLAWASVPFYDWFCRVTGFGGATGVAEAGSDTILDKTIKVRFDASKERGMPWEFRPVQTEMELRIGETGLAFYEAYNPTDRPVAGQASYNVAPYSAGGYFDKIACFCFEEQVLQPGERVQMPVTFFVDPEIVNDRDAKYVHTITLSYTFYEIDLPEGYAALDAGEKTNTN
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TRPA_HISS2
Sequence: MGYFEQKFLQLQKQKQGAFVPFVTLCDPNFDRSFEIICTLVDNGADALELGFPFSDPLLDGSVIQAANHRALNAGCSTKESFQLIAKVRSKYPDIPISLLLCANLIYAQTLDGFYQRCAEVGVDAVLVADIPLLASEPYIQSAQKYDIQPVFICPPNADETTLKAVAEKSKGYIYLVSRAGVTSAENQQSAKNLANLIKGLKKYGSAPILQGFGIAQPQQVKDVLKSGVAGAISGSAIVQIIEQNLTDREKCLSELAEFVQKMKQATLL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ARGJ_PARMW
Sequence: MVPVSLGCAMQSPWQLVSGGVTSPQGFQASGIAAGLKPSGKLDMALLLAPEQAVCAGSFTTSVVRAACVDLCAERLAANGGQARAVLINSGQANACTGDRGLIDSQRATQALADQLGLDAEALLICSTGVIGVPIPMPKLLAGLDPLVAALSATGGEAAATAILTTDLVSKQVALEAELGGRRVRIGGIAKGSGMIHPDMATMLGFFSCDAGLDPSIWKAMVGQAVQRSFNAITVDGDTSTNDTVLAFAAGDPLDSVHHAALEQGLTEAMQHLAKAIARDGEGATCLIEVQVEGALDEPSAQRVARTIVGSSLVKTAVHGRDPNWGRIVAAAGRSGVPFDPEQVALWIGPHQLMQSGQPLSFDPEAASRVLRSETVQIRIQLGDGPGNGLAWGCDLSDQYVRINADYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECH_CHICK
Sequence: MDEERLSDNVRLYKGGSIRQGLRSFAAVYVLLALSFLLLTLLSSVSLARIAALSSKLSTLQSEPKHNFSSRDSLLFPCGAQSRQWEYFEGRCYYFSLSRMSWHKAKAECEEMHSHLIIIDSYAKQNFVMFRTRNERFWIGLTDENQEGEWQWVDGTDTRSSFTFWKEGEPNNRGFNEDCAHVWTSGQWNDVYCTYECYYVCEKPLPK
What is the function of this protein?
Hepatic lectin is a membrane receptor protein that recognizes and binds exposed N-acetylglucosamine moieties of plasma glycoproteins, thus mediating their clearance (from the circulation) and endocytosis.
What are the official names of this protein?
Hepatic lectin.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: ASTE_SALSV
Sequence: MDNFLALTLSGTTPRVTQGKGAGFRWRWLGHGLLELTPDAPVDRALILSAGIHGNETAPVEMLDKLLSALYSGSLTLTWRVLVVLGNPQALAAGIRYCHSDMNRMFGGRWQSFAESDETRRARELELSLETFFSSGQARVRWHLDLHTAIRGSHHLRFGVLPQRDRPWETDFLAWLGAAGLEALVFHQAPGGTFTHFSSEHFGALSCTLELGKALPFGQNDLTQFSITSQALSALLSGVEMSTSSSPPLRYRVVSQITRHSDKFTLYMDAQTLNFTAFAKGTLLAEEGDKRVTVTHDVEYVLFPNPSVACGLRAGLMLERLP
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.