PharMolix/UniProtQA huggingface dataset:
Protein: TX1_CERMR
Sequence: DCLGWFKSCDPKNDKCCKNYTCSRRDRWCKYDL
What is the function of this protein?
Inhibits many voltage-gated sodium channels and one voltage-gated calcium channel (Cav2. 2/CACNA1B (IC(50)=400 nM), Nav1. 2/SCN2A (IC(50)=3-70 nM), Nav1. 1/SCN1A (IC(50)=523-1060 nM), Nav1. 7/SCN9A (IC(50)=129. 1-5120 nM), Nav1. 4/SCN4A (IC(50)=263-888 nM or >10 uM) and Nav1. 5/SCN5A (IC(50)=188-323 nM or >10 uM)) (PubMed:16267209, PubMed:27129258, PubMed:28880874, PubMed:29703751).  It acts by shifting the voltage dependence of channel activation to more depolarized potentials and by blocking the inward component of the sodium current (PubMed:16267209).  It shows moderate affinity for lipid bilayers (PubMed:29703751).  On Nav1. 7/SCN9A, it has been shown to interact with the S3-S4 loop of domain DII (site 4) (PubMed:27129258).  Is significantly more potent against Nav1. 2/SCN2A than the other Nav channel subtypes (PubMed:16267209).  In vivo, this toxin causes general ataxia, lack of response to stimuli, and semiparalysis (PubMed:16267209).  After a few minutes, the mice are unable to stand, and breathing is reduced in rhythm and intensity (PubMed:16267209).  Symptoms gradually increase with progressive slowing of breathing and flaccid paralysis, death occurred within 10 to 20 minutes post injection (PubMed:16267209).  Animals remain totally flaccid, and no symptoms of excitatory neurotoxicity are observed (PubMed:16267209).
What are the official names of this protein?
Beta-theraphotoxin-Cm1a, Beta-TRTX-Cm1a, CcoTx-I, Ceratotoxin-1, CcoTx1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 04 (CcoTx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYW_STAAN
Sequence: METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVDRFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGITNLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKMEKAMGLGRKR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_MICAN
Sequence: MATLQQQKIRIRLKAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MRAY_LEPIC
Sequence: MFYYLYDLYFNHLDSLRIFSYVTFRALMAGLTSMLVTFWFGHKIIDFLYGLKFRESVRDDGPKSHEIKKGTPTMGGLLIIGSLLISVLLWGNLKNPNVILLSVFSLSFSVLGFADDYMKSVKKIKGGMRARTKFILSILISFIFCILFFYYTGTTGQTGKISFQLTDLFFPFIKGPVIALGIIAIPFSILVIIGSSHAVNLTDGLDGLATGTVLISVMTLGVIAYFSGTPIVANYLNIPYLPGAHEYSVFLSALTGALFGFLWFNAHPAQVFMGDTGSLFLGATLGMIVILLKKEILLLILGAIFVSEALSVILQVGSFKLTGKRIFKMAPLHHHFELGGLKETKIVIRFWIIAVILAIISLSTLKIQ
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSY_SHESM
Sequence: MSQLTLTLLMIVAAYLAGSVSSAVLVCRMRGLPDPRSQGSGNPGATNVLRIGGASSAAMVLFFDMLKGALPTYLAYLMGIDAISLGLIAIAACLGHIYPIFFGFKGGKGVATAFGAMAPIGDDLAICLMASWVVLVLISRYSSLAAIITALLAPLYTWWLDDRFTIPVAMLSTLIIIRHKENIQRLLKGEESKVSRKKRPKTP
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU1C_ZYGCR
Sequence: MSSFDLKQRAVEWFSNLGIPTQIATFVWICVPIVVLILGITLGVLVLVWLERKISAAVQQRIGPEYAGPLGTIQALADGLKLILKEDIIPSRADKWLFALGPAIVVIPVLLSFLVIPFNHQLIVADISIGMFFWIAVSSVAPVGLLVAGYGSNNKYAFLGGLRAAAQSISYEIPLALCVLSVVLMSNSLSTIEIVEQQSRFGILGWNIWRQPVGFIAFVISALAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLFASSLFVTILYLGGWSPNISFEQVFNWEQGEQLFAVLDGLIAFAITLSKAYLFLFASILTRWTLPRVRMDQLLDLGWKFLLPVALGNLLLTASFELALL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PRMA_HAEIG
Sequence: MAWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALFDAETDMAEIVRLLKEAKHLDSNTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDKSVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELYPIISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAG2M_AGEOR
Sequence: MRAIISLFLISAMVFSMIQAVPEEXGLQLSEDERGGCLPHNRFCNALSGPRCCSGLKCKELSIWDSTCLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1m, U2-AGTX-Ao1m, Toxin-like structure Agel_12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSTU9_ARATH
Sequence: MDEEVENKVILHGSFASPYSKRIELALRLKSIPYQFVQEDLQNKSQTLLRYNPVHKKIPVLVHNGKPISESLFIIEYIDETWSNGPHILPEDPYRRSKVRFWANYIQLHLYDLVIKVVKSEGEEQKKALTEVKEKLSVIEKEGLKEIFSDTDGEPTVTNETMSLVDIVMCTLLSPYKAHEEVLGLKIIDPEIVPGVYGWINAINETSVVKDLSPPYEQILEILRAFRQMSLSPVLETYQS
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U9, AtGSTU9, GST class-tau member 9, Glutathione S-transferase 14.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: EIN21_POPTR
Sequence: MDTEFANANHPLHFLHRLLPAVGPGLLIAIGYVDPGKWAATVEGGARFGFDLVLPMLLFNFVAILCQYLSARIGVITRKDLAQICNDEYDKWTCMFLGVQAALSVIALDLTMILGIAHGLNLLFGMDLSTCVSLAAAEAILFPFFATLMERCKASFLCTCIAGFILLLYFFGVLISQPGIPLSINGTRTKLSEESVFALMSLLGASIMPHNFFLHSAIVLQHQGPPNISRDALCLNHFFAILCIFSGIYLVNFVLMNSAANVFHSTGLVLLTFPDAMSLMEQVFRSPVAPFGFSLILFFANQITAFSWNLGGQVVLHNFLRLDIPNWLQRATFRIIAVVPALYCVWTSGVEGIYQLLILTQVMVALLLPSSVIPLFHIASSRQVMGVYKISPFLEFVALISFMGMLGIKIIFVVEMVFGDSDWVGTLRWSTVSGSSTSYIVLLITACSSFCLMLWLAATPLKSATRLDAQVCNWDVQNAVSEPSTLIEEEFLTENICTGEELIERQEQLPEPGKSFESYSNITVANADPDLPETIMESDQELHLTTIKEKHSEVAFSSPQTFYEETSPTTESASLSASVNLVPDAELLVAKKAKIESMDPVEKTLDIEGELHTEKEDDEGDNWEPEDSSKGVPGSTLSLTSDGPGSFRSLSGKSDAGGNGAGSLSRLAGLGRAARRQLAAVLDEFWGQLYDFHGQITQEAKTKKLDALGVDLKLASSQLKVDTAGKESSGYFSLVGGRASDSLINSSLCDSPKQLRVQSNIDSSYGVQRGPSSLWSNHMQLLDAYVQGPSQSIADSSERRYSGVRTPPSSDGWDNQPATVHGYQIASIANRIAKDRGFSSLNGQMESPAPISPSLGPRNYRDPLTVSMGKNLQNGLSSSQASGFQNLAVTRNSPLQSERPYHDVYSGSADDTGMSANTKKYHSLPDISGLAGPYRDLYMSEKNAQWDKSAGFGSSVGRSAYEQSYYSNTGSGAGGPLSFNGLSKGHGDAFSLHMTPDPGSLWSKQPFEQFGVADKIRAVGSGLGNRSNSINREVTSPVDSEAQLLRSFRHCIVKLLKLEGSDWLFRQNDGADEDLIDCVAARERYLYEAETREMNHVDHMGGSTYLYSDRKSGSALRNDDASITNIMVSSVPHCGEGCVWRSDLIISFGVWCIHRILDLSLMESRPELWGKYTYVLNRLQGIIELAFSKPRTPMSPCFCLQIPASHQHRSSPPASNGMLPPASKPGRGKCTTAATLLDLIKDVEIAISCRKGRSGTAAGDVAFPKGKENLASVLKRYKRRLSNKLIGSK
What is the function of this protein?
Trafficking signal inducing ethylene response (By similarity).  The nuclear localization is both necessary and sufficient to activate EIN3-mediated transcription and ethylene responses (By similarity).
What are the official names of this protein?
Ethylene-insensitive protein 2.1, PotriEIN2.1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
Protein: QUEC_CAMJE
Sequence: MSKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKSYILDVSFIKDIGGNALTDKSIDIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCESIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVCIKTPLVRLNKAKIVELALKENVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PTH_CHLTR
Sequence: MVKLVVGIGNPGRQYVWTRHNIGFLLLDSLASRFLGAFREAPRLYASFAKVEISSEAVVLMKPTTYVNLTGKAVLAAKKFFDVSMEDILVVADDINREFGFVRFRQDCGSGGHNGIKNTTQILQSNHYWQLRLGVGRPSYPGAEGVADYVLSSFSLNEKEKLNDFLEKGIEEILPWLGC
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_THEFY
Sequence: MRCPFCHNQDTRVIDSRAAEEGTAIRRRRSCPACERRFTTQETVLLMVTKRSGATEPFSRSKIIAGVRRACQGRPVTEDALALLGQRVEEEIRSRGVAEVSSHEIGLTILGPLRDLDEVAYLRFASVYRSFESLEDFEREIAELRAERTATQG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: THII_THEP3
Sequence: MQDILLIKYGELALKGDNRSFFENKLIKNIKHALSDFKEVKVEKTHGRIYVECDGDIEEVIERLKKVFGIVGITKAKKTDLNLDEIFKAAVELMKGHEGKTFKVETKRPNKSFPYNSMEVSRRVGAAVLKNIKNLKVDVHNPDVLLNVEIREMAFVYAGVIEGIGGLPLGTNGKATVLLSGGIDSPVAAWMMMKRGVEVEAVYFHSPPYTSERAKDKVVDLCKVLSQYGQRIKLHVVHFTDLQLEIYEKCPPKFTTIIMRRMMMKIAEKIAQKNGSMALITGESLGQVASQTIESLYVTNASVSMPIFRPLIGMDKTEIIDLAQKISTFEISIRPYEDCCTIFVPKHPATKPKLDKVIEAEEKMEYQKYIDDFEEEVIEV
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGCX_SALTY
Sequence: MTFSVQETLFSLLRLNGISGHENSIANVMQHAFEQQAKDVWRDRLGNVVARYGSDKPDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQITMPGSIVTLAGRSGDIMGCIGIKAYHFAKGDERTQPPALDKLWIDIGAKDKADAERMGIQVGTPVTLYNPPHCLGNDLVCSKALDDRLGCTALLGVAEALASTPLDIAVFLVASVQEEFNIRGIIPVLRRVRPDLAIGIDITPSCDTPDLQDYSDVRVNHGVGITCLNYHGRGTLAGLITPPRLLRMLETTAHENNIPVQREVAPGVITETGYIQVELDGIPCASLSIPCRYTHSPAEVASLRDLADCIRLLTALANMSPEQFPIEPETGATQEARP
What are the official names of this protein?
Putative aminopeptidase SgcX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M42 family.
Protein: DAPF_ACIC1
Sequence: MDDVPFLKGHATRNDFVILPDHDDELELDAALVRAICDRRRGLGADGILRVVAVPADDAPVSSAGATADAAAGRPPQPSAGRPPQPAAARWFMDYRNADGSVAEICGNGIRLFARYLVDAGLEEAGRFLVGTRIGPVPVDVPPAGDVTAWLPAPELRGGGRARFDGRMLEGVRVSVGNPHLVCVVDTLADVDFTRAPVLDSDEFPDGANVEVVEIERPGVLRMRVYERGVGETWSCGSGACAVAAVAEGAERIPRPADGWWRIVVPGGELRIRFDGDRVALAGPAVVVAEGRLHLAALEKSDG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_STEME
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYQTLDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIDPVPGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYITGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFTEKDRSRGIYFTQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNTIIREACKWSPELAAACEVWKEIKFEFQAMDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGK_RHILO
Sequence: MAAFKTLDDIGNISGKRVLVRVDLNVPVADGKVTDATRIERIAPTIAELSGKGAKVILLAHFGRPKDGPSPEFSLEPIARATAEVLGRPVGFASDCVGDMAGSAVAAMNKGDVLLFENTRFYKAEEKNDPAFSERLAANGDIFVNDAFSAAHRAHSSTEGLARLLPSFAGRTMQAELEALEKGLGNPVRPVVAIVGGAKVSTKIDLLMNLVKKVDALVIGGGMANTFLAARGTDVGKSLCEHDLAPTAKQIMIEAAEAGCAIILPVDGVVAKEFKAGAACETVAISDVPADGMILDVGEKTVKTIGEWIDRAATLVWNGPLGAFEIEPFDHATVAAAKHAAARTKAGKLVSVAGGGDTVAALNHAGVADDFTYVSTAGGAFLEWMEGKPLPGVDVLKR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_SALPK
Sequence: MNTILAQQIASEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKMLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAICYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RSD_ECOUT
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALM_LACHE
Sequence: MKTSFNKYGRKDGKDLCEIVLENDHGMIVKVLNYGATLEKVLLNDENMILSLNSPADYSQERNYLGGTVGRIAGRVRKGQWRHGLETHQLPINDGENHIHGGIGTDTEVWDFKPSCSENSARVDLTLLD
What is the function of this protein?
Mutarotase converts alpha-aldose to the beta-anomer.  It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
What are the official names of this protein?
Aldose 1-epimerase, Galactose mutarotase, Type-1 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the aldose epimerase family.
Protein: KAD_NEIG2
Sequence: MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVGLDAVVEIDVSDSVIVDRMSGRRVHLASGRTYHVTYNPPKTEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSKLEGEHAPKYIKVDGTQAVEAVKAEVLGALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z3H7B_HUMAN
Sequence: MERQKRKADIEKGLQFIQSTLPLKQEEYEAFLLKLVQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKALEDSEKALGLDSESIRALFRKARALNELGRHKEAYECSSRCSLALPHDESVTQLGQELAQKLGLRVRKAYKRPQELETFSLLSNGTAAGVADQGTSNGLGSIDDIETDCYVDPRGSPALLPSTPTMPLFPHVLDLLAPLDSSRTLPSTDSLDDFSDGDVFGPELDTLLDSLSLVQGGLSGSGVPSELPQLIPVFPGGTPLLPPVVGGSIPVSSPLPPASFGLVMDPSKKLAASVLDALDPPGPTLDPLDLLPYSETRLDALDSFGSTRGSLDKPDSFMEETNSQDHRPPSGAQKPAPSPEPCMPNTALLIKNPLAATHEFKQACQLCYPKTGPRAGDYTYREGLEHKCKRDILLGRLRSSEDQTWKRIRPRPTKTSFVGSYYLCKDMINKQDCKYGDNCTFAYHQEEIDVWTEERKGTLNRDLLFDPLGGVKRGSLTIAKLLKEHQGIFTFLCEICFDSKPRIISKGTKDSPSVCSNLAAKHSFYNNKCLVHIVRSTSLKYSKIRQFQEHFQFDVCRHEVRYGCLREDSCHFAHSFIELKVWLLQQYSGMTHEDIVQESKKYWQQMEAHAGKASSSMGAPRTHGPSTFDLQMKFVCGQCWRNGQVVEPDKDLKYCSAKARHCWTKERRVLLVMSKAKRKWVSVRPLPSIRNFPQQYDLCIHAQNGRKCQYVGNCSFAHSPEERDMWTFMKENKILDMQQTYDMWLKKHNPGKPGEGTPISSREGEKQIQMPTDYADIMMGYHCWLCGKNSNSKKQWQQHIQSEKHKEKVFTSDSDASGWAFRFPMGEFRLCDRLQKGKACPDGDKCRCAHGQEELNEWLDRREVLKQKLAKARKDMLLCPRDDDFGKYNFLLQEDGDLAGATPEAPAAAATATTGE
What is the function of this protein?
May be a specific regulator of miRNA biogenesis.  Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 7B, Rotavirus 'X'-associated non-structural protein, RoXaN.
Protein: VSTX1_ACAGO
Sequence: MKFSVLVFILGLVLLLALSSATEMEENARACGSFMWKCSERLPCCQEYVCSPQWKWCQNP
What is the function of this protein?
Inhibits sodium channels Nav1. 7/SCN9A and potassium channels Kv11. 1/KCNH2.  Also binds the voltage-sensor domain of the potassium channel KvAP (from the archaeon Aeropyrum pernix) with very slow apparent binding kinetics and affects channel gating.  Reaches its target by dynamically partitioning into anionic or zwitterionic headgroup lipid membranes.  May bind to the open state of KvAP.
What are the official names of this protein?
U1-theraphotoxin-Agm3a, U1-TRTX-Agm3a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 63 (VsTx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DTDA_NATPD
Sequence: MLAIVVSRADEASEHIGRKLRSLADWTEHEDERRADGAGGGTYYRTDRAELRIFDDLHIHLDGAASAFEEPDLLVFASRHSGDTGPLLTAHATGNFGPAEYGGGDGSLARAAPNALSAVRDAFETHAPDDYDVGIECTHHGPSTVGCSSLFVELGSGPDQWQDSEGAAAVARSILSLRGVEPHTERTVVGFGGGHYAPRFDRVLTDTDWGVGHVAADWSLTELGDPRDSRAVIAKAFQASGTEFALVDGDRPELEAVIEDLGFEVLSETFLQETTGVPLSLVGRLEDDCGPIDDGLRLGEPATGYDGEFVTEELPDELLDEANGVDRTAVREAADAVALAYGTADGGSLAVGPVALAAADDYRSLVESLAAVLDTKYDSVEIEASTVIAHREAFDPELARDAGVDEGPAFGKLSSGASVDVDGETVTPDDVHRVRERRFEF
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: TSN2_HUMAN
Sequence: MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI
What is the function of this protein?
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.
What are the official names of this protein?
Tetraspanin-2, Tspan-2, Tetraspan NET-3.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS20_ECO27
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.