PharMolix/UniProtQA huggingface dataset:
Protein: NDK_CHLCV
Sequence: MEQTLSIIKPDSVGKAHIGEIVAIFEKSGFRIAAMKMVHLSVKEAEGFYAVHKSRPFFQELVDFMISGPVVVMVLEGDNAVVRNREIMGATNPQEAAQGTIRAQFGESIGINAVHGSDSLENAAIEINYFFSKIEIVNSAK
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECD_HELPY
Sequence: MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKDIKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAGFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPILDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALVGGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFALTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPA65_NEIGO
Sequence: ASKGNGRGPYVQADLAYAAERITHDYPEPTGAKKAQLSTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWKESNSSIKKVTEDIKDNYKETKTEHQENGTFHAVSSLGLSTIYDFQISDKIKPYIGVRVGYGHVRHQVRSVGQETITVTPKPKNGTQGGPVKSTSPIPAYHENRSSRRLGFGAMAGVGIDVAPGLTLDAGYRYHYWGRLENTRFKTHEASLGVRYRF
What is the function of this protein?
Implicated in a number of adherence functions.  OPA proteins are implicated in pathogenesis and are subject to phase variation.
What are the official names of this protein?
Opacity protein opA65.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TSP4_HUMAN
Sequence: MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFDN
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling.  Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling.  Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload.  May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury.  May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner (By similarity).
What are the official names of this protein?
Thrombospondin-4.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: B3A2_HUMAN
Sequence: MSSAPRRPAKGADSFCTPEPESLGPGTPGFPEQEEDELHRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGPGRKPRRRPGASPTGETPTIEEGEEDEDEASEAEGARALTQPSPVSTPSSVQFFLQEDDSADRKAERTSPSSPAPLPHQEATPRASKGAQAGTQVEEAEAEAVAVASGTAGGDDGGASGRPLPKAQPGHRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQSGREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMPV
What is the function of this protein?
Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:15184086, PubMed:34668226).  Plays an important role in osteoclast differentiation and function (PubMed:34668226).  Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity).  Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses (By similarity).
What are the official names of this protein?
Anion exchange protein 2, AE 2, Anion exchanger 2, Non-erythroid band 3-like protein, BND3L, Solute carrier family 4 member 2.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PAND_ANAD2
Sequence: MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHIWNITRGTRLQTYAIKGERGSGIICINGAAAHLNRPGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAVEVPGPARRVTA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_BACC3
Sequence: MRLRHKPYAMDRINEYSHFVIGNPEERAGNWKEVFGNEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKDAEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQGLFEYSLMSMAEYGMLLTYLSLDLHNSDFEGNIMTEYEEKFSSKGHRIYRVEAKYRTEPMQ
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: KUP1_LEGPL
Sequence: MKKNRFTYGLALGALGVVFGDIGTSPLYALKVTLSGIPINQFNILGVLSLIFWSLIIVVSFKYLMIIFRADNNGEGGILALLALMKHKSTKYQPLFYIVAIFGAGLLLGDGMLTPAISVVSAVEGLGTLSDKLYPYVLPIASLILILLFSLQATGTGRIGYLFGPLILVWFITIAILGILQIAEHPVVLKAINPYYAIAFLVDEGLQGYLLLGGIFLVVTGGEALFADIGHFGKNPIRFSWFFAALPCLLLNYFGQGANLIVRPEAISNPFFMIAPSWFYLPLIIIATVATVIASQAVITATFSLTKQAVLLGLCPKIPIVQTSMLHSGQIYVPQINFILFIGTMAFCLAFKTSDNLAHAYGIAVNLEMLLVDAMVAYAAISIWRWSIFNVMFLFGLFLLIDLAFLGANTHKFITGGWVPIVLAFFIAFIMYSWRYGLEYLRDNFYMNKEDISKILKQLQYKSLNQLPGVSAIFITDVYDKSGGSFLHFLKLSRSVPENVLIVNYIVDNIPYVHYSQRYEIVCLDEKVCKLVIHYGFMETINIPRSLEKACNKNILPFKFNVDTATFMVEIPNIMASKEKRSLSFYWQEKLFAFLMRNYSANLNIEFYKLPYNRTIAIGTYCIL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DUT_RHILO
Sequence: MRAALQNSSVIGPTVGFVRLPHAEGLPLPAYESTGAAGMDLRAAVPDDRPLLILPGKRSLVPTGLILEIPEGMEGQVRPRSGLAFKHGLTVLNSPGTVDSDYRGEVKVLLINLGDEDFAVTRGMRIAQIVFAVVTQAAVEERSLAGGTARGSGGFGSTGTV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL35_CAUVN
Sequence: MPKLKTKSGAKKRFKLTATGKLKAGVAGKRHRLIGHNGKYIRQNRGTKVMSEADAKIIRTYLPYGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PROF_CLYJA
Sequence: MSWDSYIDNLVAQTKDASGTAHSDRACIIGLDGGAPWTTAGHANALKLQGTEGANIAKCFKSKDFSAFMAGGVHAEGLKYQFLREEDAKLVLAKKKGEGAITLQASKTAIVIAHCPEGGQQGNTNKGVSVIAEYLESLGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HSP12_YEAST
Sequence: MSDAGRKGFGEKASEALKPDSQKSYAEQGKEYITDKADKVAGKVQPEDNKGVFQGVHDSAEKGKDNAEGQGESLADQARDYMGAAKSKLNDAVEYVSGRVHGEEDPTKK
What is the function of this protein?
May play a role in a switch from carbohydrate utilizing metabolism to fatty acid utilizing metabolism.
What are the official names of this protein?
12 kDa heat shock protein, Glucose and lipid-regulated protein.
What is the protein family that this protein belongs to?
To S.pombe hsp9 and C.albicans WH11.
Protein: NU5C_PSINU
Sequence: MEPLYGYAWIIPLCPFGASVLLGLGLFCLPGATGILRRACAIMSTLLLSVSMVISPNLFSQQINGSPTHQSSWSWIPHKNIPLEVGFFIDPLTSIMLILVTTVGVLVMIYSDSYMSHDQGYVRFFVYLSFFTASMLGLVLSSNLVQIYIFRELVGMCSYLLIGFWFTRPSAANACQKAFITNRVGDFGLLLGILGIYWITGSFEIHDLSERFDELIANNGINLLLANTCAILLFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMFHFFKALPLTMSFISWIGAITALMGATLALAQKDLKRGLAYSTMSQLGYMMLAMGIGSYRAALFHLITHAYSKALLFLGSGSVIHSMEPIVGYSPDKCQNMALMGGLRAYMPITGITFLFGTLSLCGIPPFACFWSKDKILADSWSYSPILGGIAWFTAGLTAFYMSRIYLLTFEGDFRANASIGTVTDAPLPSRHSLYVGNLTKDSGNVIHTVPQFVQDEAVPNKSFGNVRNPSSSSPPKRNLRFPEESDFLMILPLVLLAIPTLFIGSLGAPFLREGFSSNLPFNWLDPILVYSIKTNSEDWLDLVLDSVPSIAVASLGILISLTLYGPTSSLPRDLREGIDPEATGTLGSLLDSIYNWSYYRGYIDGLYNLTFVRGMRTLAKTIYSFDRWIVDGIVNGIGISGLFGGVGMRYGGGRVSSHLIGLITGLVSLLILLIRNAGFFSNISHEYYPLFFFER
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NUOK_BURO1
Sequence: MLTLAHYLVLGAILFAIAIVGIFLNRRNVIIILMSIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
Protein: Y4558_PSEA7
Sequence: MREHFNDGIEFARFLAHRFVTDKAPNSAAALTYTTLFAVVPMMTVMFSMLSLIPAFHGMGESIQTFIFRNFVPSAGEAVETYLKSFTTQARHLTWVGVVFLAVTAFTMLVTIEKAFNEIWRVRQPRRGVGRFLLYWAILSLGPLLLGAGFAVTTYITSLSLLHGPDALPGAETLLGLMPLAFSVAAFTLLYSAVPNARVPVRHALMGGMFTAVLFEAAKTLFGLYVSLFPGYQLIYGAFATVPIFLLWIYLSWMIVLFGAVLVCNLSSSRLWRRRSLPKPIVLLGVLRVFHQRQQLGQSMRLVHLHRAGWLLPEDEWEELLDFLEKEQFVCRVGGGEWVLCRDLGSYSLHRLLNRCPWPMPSRERMPAQLDEAWYPAFQQAMERLQAEQERLFGESLAHWLAEGNASAKVT
What are the official names of this protein?
UPF0761 membrane protein PSPA7_4558.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_LIMRD
Sequence: MSDKQQVAAALAQALPEMDVKEIEAKIERPKDSSNGDYAFPTFFLAKTLHKAPQMIASELVEKVDQNGFEKVVVAGPYINFFLDKAQVGAKILQTILADPEHYGEIDLGHQSNVTIDYSSPNIAKPMGMGHLRSTMIGEAVARILEKVNYNLIRIDYLGDWGTQFGKLMAAYEMWGDEAEVKKDPINTLLKYYVRINNEADEHPEYTEAGRNWFAKLEHGDEEAWRLWHWFREVSLERFQRVYKMLDVNFDSFNGEAFSAQKMEEPIQLLRDKDLLKPSRGAEIVDLDEYNLPPLLIIKSNGTTTYITRDLATALFRKRMYGHAKSLYVVGAEQETYFKQLRAALKEMGFNWWDQIEHISFGLMNLNGKKMSTRKGNVVSLEDVLNDSIDLARKQIAEKNPDLENADEVAKEVGVGAVIFHDLKNYRRNAVNFKLEDVVKFEGETGPYVQYARARAESILRKGGIRDFSDVDLTKAGAEAWELISFLGQYSEAIKRAALNYDPSVIAKYALELAKKFNQYYAHTRILDKDEAQPARLALTQAVSDVLKSALDLLDIKAPDEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPG1_SCHPO
Sequence: MADARKNNVTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRNTEITFSIWDLGGQREFVNMLPMVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFMTFPREDQEEITKQARRYAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDLKCTIPEIKNVGDPILEYIDR
What is the function of this protein?
GTP-binding protein essential for the induction of septum formation at G2 and pre-START stages of mitosis.  Acts via the cdc7 protein kinase pathway.
What are the official names of this protein?
Septum-promoting GTP-binding protein 1, GTPase spg1, Sid3 protein.
Protein: GMHA_GLAP5
Sequence: MYQQQILIELQEAQQVLNDFINDQHNLKLIQEAALLITDSFKNGGKILSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDPSHLSCVSNDFGYEYVFSRYVEAIGQKGDILFCLSTSGNSKNVINAIIAAKAKGMKIIAMTGKDGGKIAELADIEIRVPHFRYADRIQEIHIKVIHILMMLIEFEMAK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_SULDN
Sequence: MPSRKADLIVGIQWGDEGKGKIVDRLAKEYDMVCRSQGGHNAGHTIWVDGVRYALHLIPSGILNPKAVNVIGNGVVLSPESIIKEMLQFENLEGRLFISDKAHLNLSYHSLIDQAREKLKGDKAIGTTGKGIGPAYSDKINRVGMRVGELLNPEKLCERIVEHFEQNRDIFAILNINMPNKNELLEELKGYSEKLSPFITDTTQLIWRALDKENKRVLLEGAQGTMLDIDHGTYPYVTSSSTISAGACTGLGINAKDIGKVIGIVKAYCTRVGNGPFPSEDLGKDGKLLGERGHEFGTTTGRARRCGWFDAVACRYASRLNGCDELALMKLDVLDGFDEVKVCVAYELNGAQIDYLPANLDDVKPIYKSFKGWDKTEGARRFEDLPKEAQDYIKIIEEITKTKVGIISTSPEREDTIIL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BURL3
Sequence: MAKISKRRQAFAAKVDRQKLYAIEEALSLVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEIVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRSNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDQGTLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SYA_HELPY
Sequence: MDIRNEFLQFFQNKGHAVYPSMPLVPNDATLLFTNAGMVQFKDIFTGIVPRPSIPRAASSQLCMRAGGKHNDLENVGYTARHHTLFEMLGNFSFGDYFKEEAILFAWEFVTKNLGFKPKDLYISVHEKDDEAVKLWEKFVPVDRIKKMGDKDNFWQMGDSGPCGPCSEIYIDQGEKHFKGSEDYFGGEGDRFLEIWNLVFMQYERSNDGVLSPLPKPSIDTGMGLERVQALLEHKLNNFDSSLFAPLMEEISELTSLDYASEFQPSFRVVADHARAVAFLLAQGVHFNKEGRGYVLRRILRRALRHGYLMGLKEAFLYKVVGVVCEQFANTHAYLKESKEMVVKECFEEEEHFLETLESGMELFNLSLKHLNENKIFDGKIAFKLYDTFGFPLDLTNDMLRSHGACADMQGFELCMQEQVKRSKASWKGKQNNADFSAILNAYAPNVFVGYETTECSAKVLGFFDSDFKEITDANPNQEVWVLLEKTPFYAEGGGAIGDRGALFKDNGEVAIVLDTKNFFGLNFSLLEIKKALKKGDQVIAQVSDERFEIAKHHSATHLLQSALREVLGSHVSQAGSLVESKRLRFDFSHAKALNDEELEKVEDLVNAQIFKHLNSQVEHMPLNQAKDKGALALFSEKYAENVRVVSFKEASIELCGGIHVENTGLIGGFRIVKESGVSSGVRRIEAVCGKAFYQLAKEENKELKNAKTLLKNNDVIAGINKLKESVKNSQKAPVSMDLPVEKIHGVNLVVGVVEQGDIKEMIDRLKSKHERLLAMVFKKENERITLACGVKNAPIKANVWANEVAQILGGKGGGRGDFASAGGKDIENLQAALNLAKNTALKALEG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_YERPP
Sequence: MKRLLVACCFLSGLISASALADASTDLQNRLSKVNSFHASFSQAVTSSDGAVVQEGEGELWVKRPNLFNWHMTSPDESVLISDGETLWFYNPFVEQATATWLKNATGNTPFMLITRNNPDDWKQYNVKQKGDDFELTPKSASGNLKQFAISVTPSGTIKSFTAVEQDGQRSAYTLKSQQSSVVDASKFTFTPPKGVTLDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: IF2_LEPCP
Sequence: MAVTTVAQFATELNRPASTLLEQLQHAGVSKASASDPLTDTDKEKLLAYLRTSHGTSGADRKKITLTKKSTSEIKQADASGKARTIQVEVRKKRVFVKRDDPTGASSESHDSQDVQELSAAEEAELQRREEEALREAEALRRQQEEEAAQRQRAAEEQARQEREARERAEREAAERAAAEAAARVAAEAAAALAAAEKAAATAPAPAPVAAVVPKAPAPAPVVAAPTLAVASLGAKPVAPAPTSGMRVIKAADIVAGEAQKQIDLDKRRKAAEAEAAAIRAMMAAPKKVMVAKKPEEPKPVVPAAGAVGKDGIKGTIHRPKTAAGAPAPGAAPGAAAKPGEKKSVKSEKLSSSWADDAKKRGAAAPASKGRAPDVRGGWKAPGGARGGRRGDRGGAVSNFTPPADVQIHEVHVPETISVADLAHKMSVKGSEVIKQLMRLGQMVTINQQLDQETAMIVVEEMGHKAFAAKLDDPDAFLEEENLAEAGESLPRPPVVTVMGHVDHGKTSLLDYIRTSRVAAGEAGGITQHIGAYHVETPRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHSKAAGVPIVVAINKIDKPDSNLDRVRSELVAEGVVPEEFGGDAPFCLVSAKTGQGIDTLLEQVLLQAEVLELNAPQEALAKGLVIEARLDKGRGPVATVLVQSGTLKRGDVVLAGQSYGRVRAMLDETGKAAQEAGPSIPVEIQGLTEVPSAGDEFMVLADERRAREIATFRQGKYREVNLNRRQAAKLENMFENMGQGAAQTLALIIKADVQGSQEALAASLLKLSTDEVKVQIVHAAVGGISESDVNLALASKAVIIGFNVRADAGARKLADGNDVDLRYYNVIYDAVDEIKSAMSGMLAPEQREEAIGTAEIRTVFVATKIGTIAGSMVTSGLVRRNCRFRLLRNNIVIYTGEVDSVRRLKDDVKEVKEGFECGIKLKNYTDIAEGDQLEFFEIKEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_NOSP7
Sequence: MKKVLSIILGGGAGTRLYPLTKLRAKPAVPVAGKYRLIDIPVSNCINSEIFKIYVLTQFNSASLNRHIARTYNFTGFNEGFVEVLAAQQTPENPNWFQGTADAVRQYLWLMEEWDVEEYLILSGDHLYRMDYRQFIQRHRDTGADITLSVIPIDERRASDFGLMKIDDSGRIIDFSEKPKGEALTQMQVDTSVLGLTKEQAQKQPYIASMGIYVFKKEVLFKLLRESVERTDFGKEIIPDASKDYNVQAYLFDDYWEDIGTIEAFYHANLALTQQPQPPFSFYDEHAPIYTRARYLPPTKLLDCQITESIIGEGCILKNCRIQHSVLGVRSRIESGCVIEESLLMGADFYQASVERQCSLIENDIPVGIGTDTIIRGAIIDKNARIGHDVKIVNKDNVQEAERENQGFYIRSGIVVVLKNAVIPDGTII
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: HUTI_STRPD
Sequence: MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPLEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQLTVDRGRIL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.