PharMolix/UniProtQA huggingface dataset:
Protein: TFP11_BOVIN
Sequence: MSLSHLYRDGEGHMDDDEDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDEERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDEFPKDFGPKKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSLQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHSVPDDGLPPQAQPPPPPGKEARAPGFALPELEHNLQLLIELTEQEIIRNDRQLQYERDVVVNLTHELEKASGALQQEQRAIASLSEVLALVEECERRLQPGCSDPLTLDECARVFQTLRDKYYEEYRMSDRVDLAVAIVYPLMKDYFKEWDPLKDCTYGTETISQWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRSIVAQWQPRNCDPMVDFLDSWAPLIPVWVLDNILEQLIFPKLQKEVESWNPLTDTVPIHSWVHPWLPLMQARLEPLYSPIRSKLASALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMVSVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGAREHIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASAVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK
What is the function of this protein?
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.  Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS).  In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.  May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix (By similarity).
What are the official names of this protein?
Tuftelin-interacting protein 11, Septin and tuftelin-interacting protein 1, STIP-1.
What is the protein family that this protein belongs to?
Belongs to the TFP11/STIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles.
Protein: RL6_XYLFM
Sequence: MSRVAKKPISIPKGVEVSVQSDMLTVKGVKGVLTFPKSDNVNVVMDGDILTLSANDPSHISLAGTVRAILSNMIKGVSIGFERKLELVGVGYRASMQGKDLNLTLGFSHPLVFVPPEGITLLTPSQTEVVVQGIDKQRVGEVAAKIRSFRPPEPYKGKGLKYAAEAIIRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HIS7_META3
Sequence: MRVFEVERTTNETNIKLRLNIDGTGNYEITTKIPFFDHILSSFVKHGSFDLSLIAEGDLEIDDHHTVEDVGICLGMAMNKIEKKNIKRFGHAIVPMDEARAMVSIDLGGRPFVVGNYIPKRDKVGELSTENIVHFFESMANNGNMNIHFEVIGENEHHKIEALFKAFGIALDNATQIDERKGIISTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_STAEQ
Sequence: MSEIIQDLSLEDVIGDRFGRYSKYIIQERALPDVRDGLKPVQRRILFAMYSSGNTYDKNFRKSAKTVGDVIGQYHPHGDSSVYDAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSQLSEELLRDINKETVSFIPNYDDTTLEPMVLPARFPNLLINGSTGISSGYATDIPPHNLAEVIQGTLKYIDQPDITINQLMKYIKGPDFPTGGIIQGIEGIKKAYETGKGKVVVRSRVDEEPLRSGRKQLIVTEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDANSESIKNYLYKNSDLQISYNFNMVAISEGRPKLMGLREIIESYLNHQIEVVTNRTRYDLEQAEKRMHIVEGLMKALSILDEVIALIRNSKNKKDAKDNLVAEYDFTEAQAEAIVMLQLYRLTNTDIEALKKEHEELEALIKELRNILDNHEALLAVIKDELNEIKKKFKVDRLSTIEAEISEIKIDKEVMVPSEEVILSLTQHGYIKRTSTRSFNASGVTEIGLKDGDRLLKHESVNTQDTVLVFTNKGRYLFIPVHKLADIRWKELGQHISQIVPIDEDEEVVNVYNEKDFKNEAFYIMATKNGMIKKSSASQFKTTRFNKPLINMKVKDKDELINVVRLESDQLITVLTHKGMSLTYSTNELSDTGLRAAGVKSINLKDEDYVVMTEDVNDSDSIIMVTQRGAMKRIDFNVLQEAKRAQRGITLLKELKKKPHRIVAGAVVKENHTKYIVFSQHHEEYGNIDDVHLSEQYTNGSFIIDTDDFGEVESMILE
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURC_YERPP
Sequence: MNTQQLAKLRTIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNSVTQHLTALGAQIYFHHRPENVLDASVVVVSTAISADNPEIVAAREARIPVIRRAEMLAELMRYRHGIAVAGTHGKTTTTAMLSSIYAEAGLDPTFVNGGLVKAAGTHARLGSSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCIDDPVVRELLPRVGRHITTYGFSDDADVQIASYRQEGPQGHFTLRRQDKPLIEVTLNAPGRHNALNAAAAVAVATEEGIEDEDILRALVGFQGTGRRFDFLGNFPLAPVNGKEGSAMLVDDYGHHPTEVDATIKAARAGWPDKRIVMLFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYAAGEPPIPGADSRALCRTIRNRGKLDPILVPDSESAPEMLAQILNGEDLILVQGAGNIGKIARKLAEHKLQPQLKDEEHHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_XYLFA
Sequence: MTTFTAKNETVQRDWYLVDAEGKTLGRLATELARRLLGKTKPVYTTHVDTGDYLVVINAEKVVVTGKKLTDKYYHRFTGYVGNLKSESLGQALQRHPERVLEIAVKGMLPKGPLGRAMYRKLKVYTGSKHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: S39A7_RAT
Sequence: MARVLRDPHWVAVGLLTWAALGLLVAGHEGHGDLHRDVEEDFHGHSHGHSHEDFHHGHSHGHGHTHESIWHGHAHSHDHGHSREDVHHGHSHGHSHDSLHHRGHGHSHGASREAGAPGIKHHLDTVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHDTPAQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHAHAHGHGHSHGDSHAHGHSHAHGDRHECPSKGKPSSEDEKEAGGLRKRRGGDTGPRDGPLKPQNPEEEKTGSDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAIGALAGTACALLTEGGAVGSEVAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVAMMVLIAHLE
What is the function of this protein?
Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels.  Acts as gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation on residues, resulting in activation of multiple downstream pathways leading to cell growth and proliferation.  Has an essential role in B cell development and is required for proper B cell receptor signaling (By similarity).  Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function.  Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity).  Has a protective role against ER stress in differents biological contexts (PubMed:28232492).  Mediates Zn(2+)-induced ferroptosis (By similarity).
What are the official names of this protein?
Zinc transporter SLC39A7, Solute carrier family 39 member 7, Zrt-, Irt-like protein 7, ZIP7.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
Protein: PHOQ_ECOLI
Sequence: MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSFDKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVAVNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSLRPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLSRELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACKYCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAREITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes.  In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG).  In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG (By similarity).  PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, or treatment with dithiothreitol).  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, which then acts on PhoP.  Mediates magnesium influx to the cytosol by activation of mgtA.  Promotes expression of the two-component regulatory system rstA/rstB and transcription of the hemL, mgrB, nagA, slyB, vboR and yrbL genes.
What are the official names of this protein?
Sensor protein PhoQ, Sensor histidine protein kinase/phosphatase PhoQ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VG45_HAEIN
Sequence: MQAINRIIAPLKRGLQLLVSRAVVSVVNDAYARQNLQLRLQSEEVADDVERFQNYGHYSVPKAGEAIVVSVGGKRSHLVAVVVDDKSVRPAGLIAGDSVLYHLEGHQLRLTENGEAILSCKKFTIETDTLDCSAQQITFDSPQTTFTGNVDIMGISTATDHQSSGISGKNHDHEERVGKPVP
What are the official names of this protein?
Mu-like prophage FluMu protein gp45.
What is the protein family that this protein belongs to?
To phage Mu protein gp45.
Protein: MURA_SPHAL
Sequence: MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQLGCSTTIEGSRPEDFGRVMTARATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLPGGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRLAGGRFTFPVVSVGATENAVMAAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMADRIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPVTLSTAPYPGFATDMQAQFMAMATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTAVVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRVYHLDRGYERLEEKLQAVGADIERISAG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMO3_HUMAN
Sequence: MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFATTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRKWFGKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWPGARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVLT
What is the function of this protein?
Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds (PubMed:10759686, PubMed:30381441, PubMed:32156684).  Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite (PubMed:9776311).  TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.  By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation (PubMed:29981269).
What are the official names of this protein?
Flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL1_RHOPA
Sequence: MAIGKRLKKIREGIDRTKLYPLDEAVKLVKERAISKFDETIEVAINLGVDPRHADQMVRGVVMLPNGTGRTVRVGVFARGAKADEAKAAGADVVGAEDLVEQVQAGNINFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKIGTVTMDVAGAVKGAKGGSVEFRVEKAGIIQAGVGKASFDADKLVENIKALADAVNKAKPSGAKGTYIQRVAVSSTMGPGVKVEPGTVH
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1, RRP-L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CSOSD_PROMP
Sequence: MEPTSSLNRGDRKKGSSLVTGSEVQSQSNGASCFITTDSEKSLVSRQASQVEQIELRTYVFLDSLQPQLAAYMGTVSRGFLPIPGDSCLWMEVSPGMAVHRVTDIALKASNVRLGQMIVERAFGSLALYHKDQSTVLHSGDVVLDAIGSEVRKRTKPSTSWTEVICAITPDHAVLINRQNRSGSMIQSGMSMFILETEPAGYVLKAANEAEKSANITIIDVKAVGAFGRLTLAGKEGDVEEAAAAAIRAIDQISNY
What is the function of this protein?
Part of the carboxysome shell, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) is sequestered (Probable) (PubMed:22155772).  It may control transport of RuBisCO reactants in and out of the carboxysome (Probable).  There are estimated to be 6 CsoS1D hexamers per carboxysome (PubMed:22155772).
What are the official names of this protein?
Carboxysome shell protein CsoS1D.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Carboxysome. Note=Fractionates with shell proteins (PubMed:22155772). This bacterium makes alpha-type carboxysomes (PubMed:19328811).
Protein: LTG13_ARATH
Sequence: MESRKIKVMATAIALIMVAMVVDAAGADKGKDKEECTAQLVGMATCLPYVQGKAKSPTPDCCSGLKQVINSDMKCLCMIIQERNDPDLGLQVNVSLALALPSVCHATADITKCPALLHLDPNSPDAQVFYQLAKGLNETVSASAPTGSASEPTSMSSTPGSSAGNNSGRTTSVPGTNHAQSFSKQWLGLEVVAHFFVIFYIFILV
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 13, AtLTPG-13, Protein LTP-GPI-ANCHORED 13, Protein YELLOW-LEAF-SPECIFIC GENE 3, Xylogen-like protein 9, AtXYLP9, AtXYP9.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RUVC_MYCSS
Sequence: MRVMGVDPGLTRCGLSVIESGQGRKVIALDVDVVRTPADEQLHRRLLIISDTVEHWMDTHRPDVIAIERVFANHNANTAMGTAQAGGVIALAAAKRDIDVHFHTPSEVKAAVTGNGRADKAQVTEMVTRILALQAKPTPADAADALALAICHCWRAPMIARMAAAEAMAAEARRKYQAKLKAARA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: IHFB_YERPE
Sequence: MTKSELIERLAGQQSHVPAKVVEDAVKEMLEHMAGTLAEGERIEIRGFGSFSLHYRAPRVGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: F16PA_RHOP2
Sequence: MDQGQTLSRLLDSYGTDARTRAVAAAVGAIAEASIEISDLIGQGALAGITGAAHGASNADGDVQKDLDVRAEAAIVAALKNVPYAALASEESDTLLMGDPQAPISIAYDPLDGSSNIDTNMTVGTIFSVIPNEPGVAPFTAPGSCQLAAGFVVYGPQTSLVLTLGDGVDIFTLDRAAKTYRLIRERVQVPADTAEYAINASNHRHWEQPVRDFVDECLAGTDGPRAKNFNMRWIGSLVAEAYRILTRGGVFLYPADSRPGYGEGRLRVLYETHPMAFVMEQAGGAASTGRERVLDVVASTTHQRSPLIMGSSDKVHRIVELHLDPAAASRTAPLFGRRGLFRT
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_SHEB5
Sequence: MPVITLPDGSKREFAHAVSTLDVAADIGPGLAKACIAGRVNGELKDACDLIETDAELSIITAKDEEGVEILRHSCAHLLGHAIKQMWPETKMAIGPVIDNGFYYDIDLEHKLTQDDIDALEKRMLQLAKTNYDVVKRVVSWQEARDTFAARGEDYKIAILDENISKDATPALYHHEEYTDMCRGPHVPNMRFCQHFKLMSIAGAYWRGNSENKMLQRIYGTAWADKKALSTHLTRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSIFLELERFIRRKLNQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCTDSQVQEEVSACIQMVYDTYATFGFENIVVKLSTRPEKRIGDDAMWDRAEEALKQALRDNNIEFTILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPSRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGRFPTWLAPMQVVVMNITDKQADYVEEVVKFFKEQGIRASFDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGIDLGKMRLEDFATKIHQQISLRSLKLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STAA3
Sequence: MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_FERAT
Sequence: MTNIRKTHPLMKIINNAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLAVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTTKDILGALLLILTLLTLTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIMGQLASILYFLLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YIPF5_HUMAN
Sequence: MSGFENLNTDFYQTSYSIDDQSQQSYDYGGSGGPYSKQYAGYDYSQQGRFVPPDMMQPQQPYTGQIYQPTQAYTPASPQPFYGNNFEDEPPLLEELGINFDHIWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMFCLLNLMSMTGVSFGCVASVLGYCLLPMILLSSFAVIFSLQGMVGIILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVFALISVF
What is the function of this protein?
Plays a role in transport between endoplasmic reticulum and Golgi.  In pancreatic beta cells, required to transport proinsulin from endoplasmic reticulum into the Golgi (PubMed:33164986).
What are the official names of this protein?
Protein YIPF5, Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5, Smooth muscle cell-associated protein 5, SMAP-5, YIP1 family member 5, YPT-interacting protein 1 A.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the endoplasmic reticulum exit sites (By similarity). Incorporated into COPII-coated vesicles (By similarity).
Protein: BCHN_RHOCB
Sequence: MSLDSPTFGCTDSPVRRERGQKAVFCGLTSIVWLHRKMQDAFFLVVGSRTCAHLLQAAAGVMIFAEPRFGTAVLEEQDLAGLADAHKELDREVAKLLERRPDIRQLFLVGSCPSEVLKLDLDRAAERLSGLHAPHVRVYSYTGSGLDTTFTQGEDTCLAAMVPTLDTTEAAELIVVGALPDVVEDQCLSLLTQLGVGPVRMLPARRSDIEPAVGPNTRFILAQPFLGETTGALERRGAKRIAAPFPFGEEGTTLWLKAVADAYGVSAEKFEAVTAAPRARAKKAIAAHLETLTGKSLFMFPDSQLEIPLARFLARECGMKTTEIATPFLHKAIMAPDLALLPSNTALTEGQDLEAQLDRHEAINPDLTVCGLGLANPLEAKGHATKWAIELVFTPVHFYEQAGDLAGLFSRPLRRRALLNGGAA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.