PharMolix/UniProtQA huggingface dataset:
Protein: DCAF1_DROME
Sequence: MSEGSGSENAAAAEAAAEAEAATEAALMAEAVAVAYQSDEEEQPEAEDMPEQAGDNQEEDAAEQQDGGEPEADEDADADDAMSVENAENESDSGGNAEETAAADRRQATKKELTQIIDKWEQQQTQNGYDPVPTLRSLAEIFEREKDVYRRKDPDPLDSRHPYRADPSCQYGLLLKLLFRKDTFMGKLLNDYLRENYFSRQNVSRSSLELNILACRLILEIMPGMETSAVFQTAEGDGTINRIYSWAEDSIEPLQSYATGLLAEAMEVSDIAINFRDLNIRLVPKMIKRLHMLLAISKSATSDVNTSMHNLSADSSTAGMLSWVACASNASAPQSPQHNGSGLGASSSQHGDASNMSILFENSRDAFSVSRYYKRMYIPLHPATADTSQMLIMRFLTSLGEYQEFLAMAFENNVMQLIFGYLENLDRRDTCLAYEVLKYLASLLCHKKFALEFISHGGLELLLKVPRPSLATTGVSIAIYYLAYCEDAMERICSMQRPLISELVRYALWILGRCHDSSKCHATMFFSLSFQFKVILDEFDAQDGLRKLYNVISVLKILDPSHNDSDNDSDFNEDVECASRQMVRHVCVALKRYMEAHFFYKYNSFLCQTNAASPAPSSAHYFNQNPTVAAKLTFDQLNDQIRTLQEHTSIRAHWQPVDQLMKLGGITMLLRIIAFSYDWVNSGRSETVRSALDVLSVCCIIPRVYVVLCERLLMLDKTTTSGFCSVLGAAAGEISSDAEVIKSALAVLCHCVCSPIIRKDSGTSLIKFGTSSRKNKANHKYAEELIERVWESVCSNNGIVVLLSLMQTKGPITDADCIRGMACRALAGLARSDRVRQIVSKLPLFASGQLQTLMRDPILQEKRAEHVIFQKYALELLERVSGKTKPLNNPLDPSLSNMHKANVIAQTRIQYNKQQLYQLIFEHLESNGLSQTAQMLQREVGLPLQTPTTRSFHQSPFDYKSLPSGSSSLSRNRLRSRMQDVNAAIMGNGDLNRSFGEDSSPAGAGGSNAGDGVSIPNFSSLNTTQTPIKIRRTDRSSVSRSIQKQAMEPGGMSVGLAEDGQLHPKRITLNTIVTEYLTNQHSLCNNPVTTCPQFDLYEPHKCPDPKPSRLLSSNYNLTSRHARTQAGFNTSRFDRRYVHTHFSPWRSIRSADYEDLEFTCCDLAGKYIIVGTQQGDGRVFNMNDGVEQFFSNCHNFSVDAIKANRAGDLVITSSFWRTPTSILWSIADDEFKLKLRLPDVTYCEFSQTVQDRLLGTQNECATLFDINTGSKVASFTPTIPNLYTKNRATLCRTDELILSDGVLWDVRSGKEIHKFDKFNQCISGVFHPNCLEIIANTEVWDLRTFHLLQTVPVLDQRNCTFSPMHVIYGASLGADRDHDMETTTYDTSFNVLDAYDYSSIATIDVKRNINDLSVSANGSLIAVVEDYSGYESKQETYVKIYAVGVKKSERSEEEDDEEVPESDEDGSDTGSENTFAIGQNLLGFPLLRNLHGSDNDDEDLDEDDDDGEPLDSDDDSDDDDGSDNGDDDGDFDVLEYFDRSSSDD
What is the function of this protein?
Probable substrate recognition component of tsome E3 ubiquitin-protein ligase complex (By similarity).  Plays a key role in cell competition via its interaction with l(2)gl.
What are the official names of this protein?
Protein mahjong, DDB1- and CUL4-associated factor-like 1, VPRBP-like protein.
What is the protein family that this protein belongs to?
Belongs to the VPRBP/DCAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATB_HELAH
Sequence: MFGMGFFEILVVLVVAIIFLGPEKFPQAVVDVVKFFRAVKKTLNDAKDTLDKEINIEEIKKETLEYQKLFEDKIEGLKGVRIEELEDAKIVAEKEIKSVQDLMQDYKQSLENNAPPKHLNKEVSNREVFHNEPPKEIELIANNNTTKHDKEKEHV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NDK_MARMS
Sequence: MALERTLSIIKPDAVAKNVIGEIYTRFERAGFKIVEAKMIQLDDELAGGFYAEHKERPFYKDLVAFMTSGPVVVSVLEGEGAVLRHRELMGATNPKEAAAGTLRADYATSIDANAVHGSDSVESATREIAYFFGK
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S14L3_RAT
Sequence: MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEAMLRKYMEFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGRKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIVVLGNSWKEGLLKLISPEELPAHFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQISRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQKAGEMTEVLTSQRYNAHMVPEDGSLTCTEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDEELTPI
What is the function of this protein?
Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
What are the official names of this protein?
SEC14-like protein 3, 45 kDa secretory protein, rsec45.
Protein: RUVC_COREF
Sequence: MNHEGLRVMGIDPGLTRCGLSVVQAGRGRTVYPVSVGVVRTPSDAELADRLLRLSQAVGEWMDDYTPDVIAIERVFERGNVSTVMNTAHAVGVLILAAAERGLPVHMYTPSEVKKAISGNGRADKKQMTVMITRILGLAEAPKPADAADALALAVCHCWRAPLLMRTRMTAVDLEHRRRQYQGKLGKAKSTLNARNNAQVTGDAQVRAGHPSQFERPDRADPR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DEOB_THEPX
Sequence: MFKRVILIVLDSVGVGELPDAYKFGDEGSNTLGHVTEKTGVELPNMGRLGLGNIIPLKSVPENPNAICGYGKMAEKSAGKDTTTGHWEIAGLFIEKPFPTYPHGFPDEIIKEFEKRIGRKVLGNKPASGTEIIKELGEEHVKTGYPIVYTSADSVFQVAAHENVIPLEELYRICEIAREILKGDHAVGRVIARPFTGTPGNFVRTGNRRDFSLKPFEPTILDMLKEDGYEVFAIGKIEDIFAGQGITGKNHTTNNDEGITATIKAMDEIKNGLIFTNLVDFDMLYGHRNDVEGYAKALKHFDNRLPEIMEKLTKEDLLIITADHGCDPTTESTDHSREYVPLLVYSPLMKHGVNLGVRSTYADIAATIAETFRVGPTKHGTSFLKELPL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_PSEPW
Sequence: MLPYPQIDPVAVALGPLKIHWYGLMYLIGIGGAWLLASRRLNRFDPTWSREKLSDLVFWLSMGVIVGGRLGYVLFYDLHAYLANPTLIFEVWKGGMSFHGGFIGVMLAALWFGKRNNKSFFELMDFVAPLVPIGLGAGRIGNFINAELWGKATDVPWAMVFPPFSDPAQLPRHPSQLYQFALEGVALFVILWLYSRKPRPTMAVSGMFALFYGIFRFIVEFVRVPDAQLGYIAFGWLTMGQLLCVPMIVGGLFLIWLAYNRKPTAKPAV
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URE11_BRUSU
Sequence: MPARISRATYAQMFGPTVGDKVRLADTDLIIEVERDLTTYGEEVKFGGGKVIRDGMGQSQLSRAEGAMDTVITNALILDHSGIYKADIGLLDGRIALIGKAGNPDTQPGISIIIGPGTEIIAGEGKIVTAGGIDTHVHFISPQQVDEALNAGITCMVGGGTGPAHGTLATTCTPGPWHIARLIQSFDGLPMNIGVFGKGNASLPGALEEMVRAGACGLKLHEDWGCTPAAIDNCLSVADHFDVQVAIHTDTLNEGGFVEDTLNAFKGRTIHSFHTEGAGGGHAPDIIRVCQYPNVLPASTNPTRPYTVNTIAEHLDMLMVCHHLSPAIPEDIAFAESRIRKETIAAEDILHDMGAFSIISSDSQAMGRVGEMIIRCWQTADKMKKQRGSLPDDRPGNDNYRARRYIAKYTINPAIAHGMAHEIGSVEVGKRADLVLWNPAFFGVKPDMVLLGGWIATAPMGDANGSIPTPQPMHTRPMFGSFGKARTNTSITFVSQAAMDEGLREKIGVDKQLVAVVNTRGGIGKHSMILNNAMPQMEVDPETYEVRADGELLTCEPVDVVPMAQRYFLF
What is the function of this protein?
Disrupting the ure1 operon causes loss of urease activity, decreased resistance to low pH killing in vitro and decreased pathogen survival when inoculated in BALB/c mice by gavage.
What are the official names of this protein?
Urease subunit alpha 1, Urea amidohydrolase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISXH_ALKCK
Sequence: MAQYIKQGKSESELKDSHGKVEQTVASLIARIEKEGETAVRELSRQFDNWDPEQFRLSAEEIEKIVRSVPDQVKADICFAQEQIRHFAEQQRASIQDIEVETRPGVFLGHKNIPVNSVGCYIPGGRYPMVASSHMSILTAKVAGVKRVIGCTPPINGEIPAATVTAMHFAGADEIYILGGVQAMTAMAVGTETIEAVDMLVGPGNAFVAEAKRQLFGRVGIDLFAGPTEVLIIADDTADGEMVATDLLGQAEHGPTSPAALITTSKKLAEETVAEIERQLQTLPTADVAKVAWEEHGMIILVDDLAEAVVEADKLAYEHVQVLTENPNYFLDHMTNYGALFLGPETNVAYGDKVIGTNHTLPTKKAAKYTGGLWVGKFLKNCTYQRCTPEASAEIGRIAERLCELEGFIGHKAQASLRVKRYGK
What are the official names of this protein?
Histidinol dehydrogenase homolog.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: FTHS_DEHMC
Sequence: MAVNDREFHLKELDPVLMKDWEIAEKAEDFLKPVKVLAMELGLTEDEIIPHGKYIAKVDFAGVLARLKDRPNGKYIDVTAITPTPLGEGKSTTTMGLVQGLGKLGKKVTGAIRQPSSGPTFNIKGSAAGGGLSQCLPLSPFSLGLTGDIDAVTNSHNLAMVALQARLQHEANNTDEFLSSRHLTRLDIDPSRVEMKWAMDFCAQSLREIIMGIGGKTDGYRMPSGFGISVSSEVMAILSVFTSLSDLRERMGKIIVAYRKNDEPVTTADLEVDGAMTALLLRAVNPNLLQTIEGQPVFVHAGPFANIAIGQSSIVADRLALKLADYHVTESGFGADIGFEKFWNIKCRLSGLKPDCAVIVVTARALKMHGGGPKVTPGAPLDPAYTTPNTKLVEKGCQNMLAHIQTVKTAGINPVVCINHFAADTHEEIDIIRRTAEQAEARVAVSHHWAKGGDGATELAEAVTDACNEPNNFHFLYPENMPLKKRIETIARKVYGANGVSYTPIAMEKLARIESMGDTQFMPTCMVKTHLSLSHDPALKGRPSGFTLPIRDILTYMGAGLVVPVAGDIKLMPGTSSDPNFKRIDVDTQTGKVKGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: UBIB_HAES1
Sequence: MKLNDIKRLYKIVRVFLSYGIDEILPHNKYTRSIRCWRMLFFWLKNKHKNKAFGLCLRLALQELGPVWIKLGQMLSTRRDLFPAEIADELALLQDNVEAFSGKIARQQIEQALGSSLENWFTDFDENALASASIAQVHTAKLKLGEEQEKEVVIKVLRPNIQPQIEADLSWMYKLAGLLPKLFREGYRLRAVEVIQEYEKTLRDELDLRVEMANAIKLRENFLDSPMLYIPKMYEAFCHKNVIVMERIYGIPVSDVETLQRNGTDMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVNPHYPENPQYIGIDCGIVGKLNESDKRYLAESFVAFFNRDYRRVAQMHVDAGWTPQDTNIDDFEQAFREVCEPIFAKPLSEISFAQVLLNLFNVAREFNMQVQPQLVLLQKTLLYIEGLGRQLYPQLDLWDTAKPFLQNWLNEQIGMKVTFKKLKAKLPYLQEHLPDFPETLMDALKQQKFISQQLVEINKKLAKQQRWQKKMFVLIVGIVIFSVTLWQFAALPLAISAGLFLVGFLVWLIGFLLP
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALLC_PHOPR
Sequence: MEKALNFEQYVNLADPKLGAEAIFATDDFFADKSRLIRTEAAEWKEDLYDDNGKWMDGWESRRKRSEGYDFCVVRLGLAGTIAGLDIDTSFFTGNFPPSASVDACYSPDGEPSDSTEWQEILSSQSLQGDSHHLHALDNEQVFTHVRLNIYPDGGVARLRVYGRPSVNWDQIGIDQEVDLAAVVNGGRALACSDEHFGKKSNILGPGRGENMGDGWETARRRTPGNDWVIVALGRPGKIGKVVVDTAHFKGNFPDSCSIQAAYVQGGTDDQVETQSLFWRELMPSQKLSAHNIQEFVEQVNDLGAVTHVRLNIFPDGGISRLRLFGFKSE
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: SYA_METPP
Sequence: MKASEIRSAFLKFFESKGHQIVASSPVVPGDDPTLLFTNAGMNQFKDVFLGFDKRPYSRATTAQKCIRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKQDAIAYAWELLTEVFKLPKDKLWVTVYAEDDEAYEIWNKQVGVPAERIVRIGDNKGARYASDNFWMMGDTGPCGPCTEIFYDHGPEIPGGPPGSPDEDGDRYIEIWNNVFMQFNRDEAGVMHKLPKPSVDTGMGLERITAVLQHVHSNYEIDLFVALLAAAKQAVDAAGAGDSDKDSPSLKVIADHIRACSFTIVDGVIPGNEGRGYVLRRIARRGIRHGYKLGARKPFFHTLVAELVRQMGEAYPELARAEARVTEVLKQEEERFFQTIANGMEILESALAGGAKTLDGETAFKLHDTYGFPLDLTADVCRERGVTVDQAGFDAAMKRQREQARAAGKFKMAAGLEYAGAATTFHGYEHLVHEGSKVTAVYVDGSAVPSAKAGDDAVIVLDHTPFYAESGGQVGDGGELRNGTSRVIVEDTQKIQADVFGHHGRVVEGEIRVGDVLNARVDGEQRARTVRNHSVTHLMHKALREVLGGHVQQKGSLVNAERTRFDFAHNAPMSDAQIAKVEAIVNAEILANAPTQARVLPMEEAQKLGAMMLFGEKYGDEVRVLDIGSSRELCGGTHVQRTGDIGLFKVVAESGVAAGIRRVEAITGDNALAYVQQLEGTVAGLAGALKAAPAEVPGRVAAVLEQLRTLEKELAALKGKLASSQGDGLLAQAVDVKGLKVLAARLEGADAKALRDTLDQLKNKLKSAAIVLAVVEGGKVQLAAGVTADATARVKAGELVNFVAQQVGGKGGGKPDLAMAGGTDPAGLGAALASVAGWVGERA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIB_PECAS
Sequence: MSVMTIQRRWLVAAGVTAAMVASPVWAAKDAVIAVGSTFTSLDPYDANDSLSQTVAKSFYQGLFGFDKDMKLINVLADSYDISSDGLTYTVKLHPGVKFHDGSAFNAAAVKVNLDRASNPDNRLKRYNLFKMIDKTEAVDDLTVKITLKTPFSAFVNNLAHPAAVMISPAALTQYGKEIGFHPVGTGPYRFVAWNQTDFVKVEKFSGYWKAGLPKLDSITWRPVVDNNTRAALLQTGEAQFAYPIPFEQAKVLEKNDKLALVASPSILHRYISMNVTQKPFDNPKVRQALNYAINKDALIKVAFSGYATPAEGPLPNSIDYSVKYHPWPYDPAKARELLKEAGYPNGFTTTLWSSHNHSTAQKVLQFTQQQLAQVGVKVQVTAMDAGQRAAEVEGKGVKETGVRLFYTGWSASTGEADWALSPLFATASWPPAQFNTAFYSNPQVDTDLANALKTTDRAEKQTLYKDAQDKIWADAPWIFLATERLVSANSKKLTGFYVMPDTLFSFEDADLTE
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Binds glutathione.
What are the official names of this protein?
Glutathione-binding protein GsiB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TDCC_ESCF3
Sequence: MSSTDNIVSGKAQHSYWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILVMLVLAYPIAFYCHRALARLCLSGANPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLHLPALNRGFVALFLLLLMAVIIWFGRDLMVKVMSFLVWPFIASLVLISLSLIPYWNSAVIDQVDLSALSLTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVFKREEYEKKFGRDFTERKCSKIISRASILMVAVVMFFAFSCLFALSPQNMAEAKAQNIPVLSYLANHFSSMSGSQSSFALTLEYAASIIALVAIFKSFFGHYLGTLEGLNRLIIKFAYKGDKSKISMSKLNTLSMVFIMGSTWLVAYVNPNILDLIEAMGAPIIASLLCLLPMYAIHKVPSLAKYRGRIDNVFVTAIGLLTISNIVYKVF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMC_SHISS
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATVDDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANCVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_STUST
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTDQAAAVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRENVQCLIGNGVVVAPDALLREITKLEEKGVPVRERLRISPSCTLILPYHVALDQAREASRSEGKIGTTGRGIGPAYEDKVARRGLRIGDLFNPERFAVKLRELLEYHNFALQ
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
Protein: COPB_STAHJ
Sequence: MNHSNHMHHDNHESHHHYSGHAHHHGNFKVKFFVSLIFAIPIILLSPMMGVNLPFQFTFPGSEWVVLILSTILFFYGGKPFLSGGKDEIAAKKPGMMTLVALGISVAYIYSLYAFYMNNFSSATGHTMDFFWELATLILIMLLGHWIEMNAVGNAGDALKKMAELLPNSAIKVMDNGQREEVKISDIMTDDIVEVKAGESIPTDGIIVQGQTSVDESLVTGESKKVQKNQNDNVIGGSINGSGTIQVKVTAVGEDGYLSQVMGLVNQAQNDKSSAELLSDKVAGYLFYFAVIVGVISFIVWMLIQNDVDFALERLVTVLVIACPHALGLAIPLVTARSTSIGAHNGLIIKNRESVEIAQHIDYVMMDKTGTLTEGNFSVNHYESFKNDLSNDTILSLFASLESQSNHPLAISIVDFTKSKNVSFTNPQDVNNIPGVGLEGLIDNKTYKITNVSYLDQHGFEYDNDLFIKLAQQGNSISYLIEDQQVIGMIAQGDQIKESSKQMVADLLSRHITPVMLTGDNDEVAHAVAKELGISDVHAQLMPEDKESIIKDYQSDGNKVMMVGDGINDAPSLIRADIGIAIGAGTDVAVDSGDIILVKSNPSDIIHFLTLSNNTMRKMVQNLWWGAGYNIVAVPLAAGALAFIGLILSPAVGAILMSLSTVIVAINAFTLKLK
What is the function of this protein?
Involved in copper transport.
What are the official names of this protein?
Probable copper-transporting P-type ATPase B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCP_ESCF3
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDPGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGDDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLDAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_DESHD
Sequence: MPRKGYIAKREILPDPIYKNRVLTKFINQIMLDGKKGTAESICYNAFELIQEKTGKDPIEVFETALKNVMPVLEVKARRVGGANYQVPIEVRTDRRQTLGLRWLVGYARKRSEKTMEERIAGELMDAANNTGGSIKKKEDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ABCG1_ARTBC
Sequence: MAWLALLGLLPLLPAIQPTWQANGYEINSTADSFVTAATPFTLRSARPPECPPCFNCQLPAFKCHQFGKCNKFNGKCDCPPGFGGDDCAEPLCGSLPDGRDRTPRKGSTCQCKDGWSGINCNMCETNDACNAMMPEREGGVCYRHHNGGETVAENYQMCEVTNRKIRDMLKEKKPQVTFSCKKEDKTCNFQFWVDQLESFYCSLDTCKWNMDITENQNLTTYQCDNIKCGCVPDRMLCETTGVSLEPLFGQLTGPAKFTSTSTKGGSNKDGSAFSEPVIDKVISDLFGDKSILLDCYSSECLYKTAVPGYKPPVKVINTPLIAGVIAGCSLFIVGVILLIWYLSRRKAYNQYHALADDSDDEGSKLMADHKPASLQFENISYYINGQQILSGIRGIAKPGQVTAIMGASGAGKTTFLDILARKNKRGVVHGDIYVNGEKFNDSEYKKVVGFVDQEDTMLPTLTVHETILNSALLRLPRDMSDAAKQQRVYEVEKQLGIHHIKDQLIGSEEGKGRGISGGEKKRVSIACELVTSPSILFLDEPTSGLDAFNAFNVIECLVNLAKSYNRTVIFTIHQPRSNIVALFDQLILLGKGKTVFSGPYSSCQSYFDNIGYSCPPGFNIADYLVDLTMHASQSRSTEEPAVNVDSHDNNFRTASSSLRAVKSVASASNASIDNASAVDSAQESLLRPKDKRRSSLKQRQDRQLYTRKRGSGLESPPDPQTDNEDGHVMSLAERAQQWLPLSRQQGQVPPQILQDPDHLPPIASGFVTDLDVLVSYYANSNVANAVRDEISSSVQDALAANGQANSQQASDAVTGQMTGYARVGLIRQFIILSSRTWKNLYRNPMLMLTHYATAILLAVLSGYLFYGLTDDIKGFQNRLGLFFFLLALFGFSTLTSLTVFSSERLLFVRERANGYYSPVTYFTAKVLFDIVPLRLIPPIIMGVIVYPMVGLIPDWPEFSKFILVLVLFNLAAAGICLLIGIVFRDPGVANLIGSLVMLFSLLFAGLLLNHDAIPASALWLQTLSIFHYAFEALIVNEVTFLTLIDHKYGLDIEVPGASILSAFGFNNLALWNDVAGLGVISGVSIIMAYAAMHFLLVEKR
What are the official names of this protein?
ABC transporter G family member ARB_01379, ABC transporter ARB_01379.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TAT_HV1ND
Sequence: MDPVDPNLESWNHPGSQPRTACNKCHCKKCCYHCQVCFITKGLGISYGRKKRRQRRKPPQGDQAHQVPIPEQPSSQSRGDPTGPKK
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: LGT_LISW6
Sequence: MGNGVQPLDPVAIQMGSLSVKWYGVIIASAVVIALLLALSEANKRKMDKEIIVDLLIWAIPISIISARIYYVIFEWDFYKNNLGEIIKIWHGGIAIYGALIGAVLTAIIFSRVKKISFWQLADVVAPSLIIAQAIGRWGNFMNQEAHGAETTRAFLEGLHLPEFIINQMFIDGIYYQPTFLYESLWNVLGFILLLIIRRTKIRSGELFLSYVIWYSFGRFFIEGMRTDSLMWGDFRVSQVLSLLLIVLSIGLIIYRRLKMNPPYYMEDKFGKVAKKK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.