PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_BACC3
Sequence: MPKGSGKVIAQNKKAFHDYFIEETYEAGLVLQGTEIKSIRAGRVNLKDAFARVHNGEVWVHNMHISTYEQGNRFNHDPLRTRKLLLHKKEIEKLAGASKETGYALVPVRIYLKNGFAKMALGLAKGKKQYDKRHDLKEKEAKREIARAFRDRQKM
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: F16PA_XANOM
Sequence: MSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGALGGVLGDAGTGNVQGEAQKKLDVLSNDILLEANAWGGHLAACASEEMDHSQPVPEQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEHFLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPDETAEYAINMSNQRHWEPAMQAYVGDLLAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQPTQLHQRVPVFLGSKNEVAAATRYHLDADKA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK4_PSEFV
Sequence: DHLPHDVYSPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin-4, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: APAH_MYCRA
Sequence: MRVIFSEDHKLRNAKTELYGGELVPPFEAPFRAEWILAAVKEAGFDDVVAPARHGLETVLKVHDAGYLNFLETAWDRWKAAGYKGEAIATSFPVRRTSPRIPTDIEGQIGYYCNAAETAISPGTWEAALSSMASAIDGADLIAAGHKAAFSLCRPPGHHAGIDMFGGYCFINNAAVAAQRLLDKGAKKIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAGAGTTANYPMGRGTPYSVWGEALTDSLKRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPDYITMGRTIAASGVPLLVVMEGGYGVPEIGLNVANVLKGVAG
What is the function of this protein?
Involved in polyamine metabolism.  Catalyzes the deacetylation of various acetylated polyamines such as N-acetylputrescine, N-acetylcadaverine, N(1)-acetylspermine, N(1)-acetylspermidine and N(8)-acetylspermidine (PubMed:8824626, PubMed:3207420).  In vitro, is also able to deacetylate L-Lys(epsilon-acetyl)coumarin, but has very low activity towards the larger tetrapeptide N-acetyl-L-Arg-L-His-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)coumarin (PubMed:21268586).
What are the official names of this protein?
Acetylpolyamine amidohydrolase, APAH, Acetylcadaverine deacetylase, Acetylpolyamine deacetylase, Acetylputrescine deacetylase, Acetylspermidine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
Protein: ARCH_SULIK
Sequence: MRSFEFFEHTADVGIRAYGKSLEEAFSNAALGVFEVITDTSKVKPIEYREIYLNGYDLENLLYKWIEELLYYYDSELMVFSKFDLMIDQDSMTLEGKAWGEKFNGKIHERRTVVKAMTYHQLSIEKTENGYVITFVVDI
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: TRPA_NITMU
Sequence: MSRISTLFGKLLQNRRKALIPFITAGDPEPGMMVPLMHELVQAGADVIELGVPFSDPMADGPTIQRSSERALKHRVSLQDVLAMVGEFRESDSSTPVVLMGYANPVEAMGYDAFTARSKACGVDGVLIVDYPPEESVKWVEYLKRQNIAPIFLLSPTTPQQRVERVASLAEGYVYYVSLKGVTGSLHLDLHDVAEKLDGLRSRISIPIGVGFGIRDGATARAVAELADAVVVGSRIIEEIERSPKAEVLTNVHRLVKSLRIAIDAASPAPSAAVKLTHL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL27_CHLPN
Sequence: MAHKKGQGASRNGRDSKSKRLGVKVGAGQKVSTGSILVRQRGTRWNPAQNVGRGRDDTLFALVDGIVVMKKTNRTYISVVPEQL
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GLO2_GLOC7
Sequence: MKIFRLPALSDNYIFLLHDPQRNIAAVVDPAEPEPVLTCLKKLGAELVTIFNTHHHGDHVGANRALIEHFPNLTVYGGEEDRGRIPGQEVFLKEGDRVQFGDRSGEVFFVPGHTRAHIAYYFPPQGEEETGELFCGDTIFAGGCGRLFEGTPAQMVNSLSKLRALPDNTRIWCAHEYTLNNLKFALTVEPENIDLQNRFSDVKIARSEGEATVPSLLGIEKLTNPFLRWDTQAIKSAMGSQDSVQVFGRLRGKKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: Y823_METJA
Sequence: MKIAITGKGGVGKTFIASTLMRLFEKNGFKVIGVDCDPNPTLALAFGVEEEIVPLSKRHDIIEERTGAKPGTYGNIFKINPKVDDLIDKVGYKIGNITLLVMGTIEEGGEGCVCPASVLLRRLLRHLILKRDEVVILDMEAGIEHFGRKTIDTVDLMLIVIEPTKKSLITAKRMKKLANDLGIKNLGVIVNKVRNEDKELLKDIIKEELGLEVLGFVPYDEEVIKSEFLGKPINLDSKAAKEIEKIFNYIIKLKNTT
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0823.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0084 and MJ0685.
Protein: 5DNU_SALAR
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGQLNAEHIALLAMYHDTSEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMAPDELRDIFAPLIDENAWSEEEQAIVKQADALCAYLKCLEELSAGNNEFKLAKTRLEKTLALRRSQEMDYFMAVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOA_PHOV8
Sequence: MIEPNYLPFILIGGGIIFVVLFFHYVPFFLWLSAKVSGVRISLVQLFLMRIRNVPPYVIVPAMIEAHKAGLSNITRDELEAHYMAGGHVEKVVHALVSASKANIELSFQMATGIDLAGRDVFEAVQMSVNPKVIDTPPVTAVAKDGIQLIAKARVTVRANIRQLVGGAGEDTILARVGEGIVSSIGSSENHKSVLENPDSISKLVLRKGLDAGTAFEILSIDIADIDIGRNIGAALQIDQANADKNIAQAKAEERRAMAVALEQEMKAKAEEARANVIQAEAEVPKAMAEAFRSGNLGIMDYYRMKNIQADTSMRENIAKPETTFGNEPLSK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: MRAY_YERP3
Sequence: MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_ACTP7
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASALIGHEIIKTTLPKAKELRRVVEPLITLAKEDSVANRRLAFARTRNVETVAKLFNELGPRFAQRAGGYTRILKCGFRAGDNAPMAYIELVDRPEVAEAATE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y8381_DICDI
Sequence: MSNSDKNNNNNTNNNNNNNNNNNGNFGIWEEPDDDSTNENEELFNNLITKTTKFIDDDEEEEEEESSWDTLYAKHVETSNTTQPFNNSNSNNNNFQTQPTNISTLNPNNNNSNNSSSGSSSSRGVRTPRGTRSNSPPQPSKNETVQKESSGDISEGFTLIDSPNDNNDNKNNNKNNNNDSNIVDDDEDEEEFPTLSKKNQKRKPKKSTSSPSSTSSPIVSPQTQTSKLESSMDVSPSSGKQSWSELLKNVADEDINNNNNNNNNNNSNQYHQEEENYYDSDDYDSSPFAIINNSSTTTNNNNNNNNNTTTTTTTTTTTNSSSLPIVNSQSFEEGEEITSDIKIGIKPKTVTVPFQSTLSLRARTKQIKKVQQQQQQSSKSKPNNNNNKFVDNNPYAVLEEEERALQSAIKASLLLNSPVDLDSKQQNVSQQKQQQEQQPTTTTNSVSSSKSKSVATTDKNRTTSTAVAPTTSSNKKANKSNKTSTANTTATTTTTASSKKNKSNSNKSSNVSNTTTTTSTTENSASEGSFIKNAVIFIFILLLMVVGFKYTQTLNQ
What are the official names of this protein?
Uncharacterized protein DDB_G0289357.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYT_THEFY
Sequence: MSAVPELRITLAGTERVVAAGTTAGQALEADGRTVIAALVNGEPRDLTHELADGDVVEEIRIDSEEGRAILRHSCAHVLAQAVQELFPEAKLGIGPPIENGFYYDFDVAEPFTPDDLKRIEKRMQEIIKQGQRFSRRAVTDEDARAELADEPYKLELIELKGGAAEAAEGAGVEVGAGQLTIYDNLHPRTGEVCWKDLCRGPHLPDTRAIPAFKLMRTAAAYWRGSEKNPQLQRIYGTAWETKDALKSYLTMLEEAAKRDHRKLGVELDLFSFPDELGSGLAVFHPKGGVVRKVMEEYSRRRHEEAGYQFVNTPHISKAGLFETSGHLPNYADAMFPPIQFEGADYYLKAMNCPMHNLIYRSRGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRARGFTQDDAHIYCTKEQMPDELDRLLTFVLDLLRDYGLSDFYLELSTRDDSPKFIGEPQEWEEATEILRQAAQKQNLELVMDAGGAAYYGPKISVQAKDAIGRTWQMSTIQVDFQQPKRFELEYQAADGSRQRPVMIHRALFGSIERFFAVLLEHYAGAFPAWLAPVQVVGIPIASEHVPYLEDVARRLREHGVRVEVDASDDRMQKKIRNAQKQKIPFMLLAGDNDVSKGAVSFRYRDGSQNNGVPIDKAIEEILTVIRERRQV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BRUAB
Sequence: MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVEKLRGQGIDVTPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVERLLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTILVTDPFHD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA5_NAJHH
Sequence: LKCHQLVPPFWKTCPEGKNLCYKMYMVSSSTVPVKRGCIDVCPKNSALVKYVCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 5, Toxin CM-8.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: THII_YERPG
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKHLEDDTLAIVRHWDHIELRTKDDNLGPEICDALTRIPGIHHILEVEDRSYSDMHNIFEQTLEAYRETLVGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVNLTRPQVTVNLEVDQDKLILVKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFIAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLARQIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVSEAKNVDIREIAQQSREQVVEVETVAELADTDVLLDIRAPDEQEEKPLKLDQVEVRSLPFYKLSSQFADLDQSKTYLLYCDRGVMSRLQALYLREQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_LAGHI
Sequence: MMSINLNLIMAFLLALAGVLIYRSHLMSTLLCLEGMMLSLFILMALLISHFHMFSASMAPLILLVFSACEAGVGLALLVKTSSNYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRGX2_MOUSE
Sequence: MEERNISGRDLRVDSNITYWGTNITAVNESNHTGMSFCEVVSCTMVFLSLIVALVGLVGNATVLWFLGFQMRRNAFSVYILNLAGADFLFICFQIGYCFHMILDIDSIPIEIDLFYLVVLNFPYFCGLSILSAISIERCLSVMWPIWYHCQRPRHTSAVICTLLWVLSLVCSLLEGKECGFLYYTSDPGWCKTFDLITATWLIVLFVALLGSSLALVITIFWGLHKIPVTRLYVAIVFTVLVFLLFGLPYGIYWFLLVWIEKFYYVLPCSIYPVTVFLSCVNSSAKPIIYCLVGSIRHHRFQRKTLKLFLQRAMQDTPEEEECGEMGSSGRSREIKTIWKGLRAALIRHKEL
What is the function of this protein?
Orphan receptor.  Probably involved in the function of nociceptive neurons.  May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
What are the official names of this protein?
Mas-related G-protein coupled receptor member X2, Mas-related G-protein coupled receptor member B10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERA_CORDI
Sequence: MSFTDTPEGFRSGFISFVGRPNTGKSTLTNALVGEKIAITANQPETTRHPIRGIVHREDAQIIVVDTPGLHKPRTLLGERLNEVVKDTYADMDLIAITVPADEKIGPGDRWILDAVKKVAPKTPLLGIVTKVDKASRDQVAVQLMELHELLGGNSEVVPVSAVTGEQRDVLLDVITRLLPEGPKFYPDDHITDDDTETRLSELIREAALSGLKDELPHSVAVQIDEILPNDEREGVLDVHAVIYVERPGQKSILIGKDGRRLGRIIHNARPEIIKILGSNVYLDLRIKVLKNWQQDPKQLGRLGF
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: YCF12_OSTTA
Sequence: MNLELIGQLVTVALVVGAGPIIIGALFARGGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DAPB_CUTAK
Sequence: MIKVAVFGAKGRMGTAVCQAVEEAEDTELVAAVDSGGDRSDASGADVIVDFTTPDAVMDNLSWAISHDINTVVGTTGFDDERYQVLRDQLADHPNIGCLVAPNFSIGAVLMMHFAEQAARFYESAEIVELHHPNKVDAPSGTARTTATKIAAARQEAGLGEVPDATKSQLNGARGAVVEGVHVHSVRLRGLVAHQEVLFGAEGETLTIRHDSMDRVSFMSGVLTGVRGVLDRPGLTVGIEGLLGLE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_MYCPU
Sequence: MNKEKTIIFSMPNTHVLAQEICDELKMKLHSVNKTIFADGEVLLSSKETVRSKDVFIVASTSHPANNNIMDLLIFVDSLKRASAKTINVILSYYGYARQDRKAEGRQPIAAKLLADLLQVAGISRIVVVDLHNPSIQGFFNIPVDDIKAQYILSKEFTIKDEKFTIVSPDHGGTIRARIMAEIISNDVKIAIIDKRRVSTNKTEVLGVIGDINNENAVIVDDIIDTGGTIVNAAEVLKKNGAKKISIVASHGIFSKGFDIFEDADVIDEVIVTNSIDNYELAKKYKKLKIVSLAPFLSKVIRSIMDSKSVSDIYAKYLESK
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_SHESA
Sequence: MQEQYNPSEIEALVQKHWHDNKTFEVTEDANKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARFQRLQGKNVLQPIGWDSFGLPAENAAINNKTAPAPWTYQNIEYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGLVYKKTASVNWCPNDETVLANEQVQDGCCWRCDTPVEQKEIPQWFIKITAYAEELLNDIDTLDGWPEQVKTMQRNWIGRSEGVEMTFGVAGSDKSFDIYTTRPDTLMGVTYVAIAAGHPLAELAAQTNPELAQFIEECKNSTTSEADLATMEKRGVATGLYAIHPITGKQVPIWAANFVLMNYGTGAVMSVPGHDQRDYEFAKKYNLPIEAVIKPVDGELDISEAAYTEKGVLFNSGEFDGLDFDGAFNAIADKLVAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVIPTPEDQLPVILPEDVVMDGIQSPIKADKEWAKTQVNGQDALRETDTFDTFMESSWYYARYCSPQADQMLDPTKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLRDAGLVNSNEPAKQLLTQGMVLADAFYYTNDKGARVWVSPLDVVTTEKDDKGRVTKAIDKDGNELVYTGMCKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASDYVAQDNSEALDVSKLTSEQKALRREVHKTIAKVTDDIGRRQMFNTAVAAVMELMNHLQKAPQTTGQDRAIIGEALTAVVRLLYPIIPHVSFTLWNELGNTNSIEDSQWPVVDESALVEDSKLIVVQVNGKVRAKITVAADADQASVEALGMADEQVIKYLDGVTVRKVIYVPGKLLSIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFD1_COCIM
Sequence: MPLDGVKNIVLVLSGKGGVGKSSVTLQLALTFCLQGRSVGILDVDLTGPSIPRLVGLEDAKITQAPGGWLPVTVHPFHTPSSDGLNGSQRANKPDDSNESSSSTVETAPQSTNFCGSLRCMSLGFLLRDRGDAVIWRGPKKTAMIRQFLTDVLWGETDYLLIDTPPGTSDEHIALAEQLLTIQQTYSLRSSRATAPKLAGAVLVTTPQAISTSDVRKEINFCVKTRIPVLGVIENMSGYTCPCCGEVSNVFSRGGGQIMAQETGVRFLGAVPIDVGFGEMVEGWKKDSTGQDQGNKATKKGQDARLDSYDDLLVERYKKCWSFSVFEEFAKKLIGLIEGSDQQ
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor CFD1, Cytosolic Fe-S cluster-deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPOH_METMA
Sequence: MTFMAIEIPEFIVPFVPWIRGTVGLVLVGAIFLGGMAAVWIERKLSADIQLRYGPSRVGKFGLLQLVADAIKLFTKEDVRPGNADRFLYDNAPVFMLTSLFLMLVAIPVGAVFIDGNLYPLAVTEMDISILFIEAVSAINIFGIFMAAYGSNNKYSLLGAFRNFARMIGYEVPLGIAIVSVAVMTGSLNIIDITSAQGSFVWNIFLQPIGFVVFFIALMADLGRLPFDQNESEEELVAGWVTEYTGMRFGLVFFAEYMHMILGSFLVALLFLGGWNVPAFVANNAVLGLIAPTGILLLKTVLVLMTIIGMRWAVPRFRIDQVVDMSWKKLLPLSLLNLAWAVGLGLYLGA
What is the function of this protein?
Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2):heterodisulfide oxidoreductase system.  The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines.  Catalyzes the oxidation of methanophenazine to dihydromethanophenazine.  It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane).  It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  It also catalyzes the oxidation of F(420)H(2) with quinones such as 2,3-dimethyl-1,4-naphthoquinone, 2-methyl-1,4-naphthoquinone and tetramethyl-p-benzoquinone.
What are the official names of this protein?
F(420)H(2) dehydrogenase subunit H, F(420)H(2)-dependent phenazine dehydrogenase subunit H, F(420)H(2)-dependent phenazine oxidoreductase subunit H, FPO subunit H, Methanophenazine hydrogenase subunit H, Methanosarcina-phenazine hydrogenase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_SHESW
Sequence: MSTNPKPTFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSDDPMKNPDAVKYDELSYSEILEKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVIMGEEEGTLIRAKKVI
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.