PharMolix/UniProtQA huggingface dataset:
Protein: MURE_ECOL6
Sequence: MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGEPSAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSAHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATDVNYHDSGATIRFSSSWGDGEIESRLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGYAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BACFN
Sequence: MVDVKTIIEESQEKMDMAVMYLEEALAHIRAGKASTRLLDGIRVDSYGSMVPISNVAAVTTPDARSITIKPWDKSMFRVIEKAIIDSDLGIMPENNGEIIRIGIPPLTEERRKQLAKQCKAEGETAKVSIRNARRDGIDALKKAVKDGLAEDEQKNAEAKLQKVHDKYIAKIEEMLAEKDKEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_SORC5
Sequence: MPRSIKKGPFIDGHLLEKIQAAQATNAKKVIKTWSRRSTILPESVGLTFAVHNGRKFVPVFVTENMVGHKLGEFAPTRTFHGHSGDKKAKVAKGGPGGR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CDS1_RAT
Sequence: MLELRHRGGCPGPGGAGTPPPREGEAAGGDHETESTSDKETDIDDRYGDLDARGDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFQEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGPNPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTWKV
What is the function of this protein?
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (PubMed:9083091, PubMed:9345289, PubMed:29253589, PubMed:30862571).  Exhibits almost no acyl chain preference for PA, showing no discrimination for the sn-1/sn-2 acyl chain composition of PAs (By similarity).  Plays an important role in regulatinng the growth of lipid droplets which are storage organelles at the center of lipid and energy homeostasis (By similarity).  Positively regulates the differentiation and development of adipocytes (By similarity).
What are the official names of this protein?
Phosphatidate cytidylyltransferase 1, CDP-DAG synthase 1, CDP-DG synthase 1, CDP-diacylglycerol synthase 1, CDS 1, CDP-diglyceride pyrophosphorylase 1, CDP-diglyceride synthase 1, CTP:phosphatidate cytidylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CARY_HALH5
Sequence: MPKRTDIQSVLVIGSGPIVIGQAAEFDYAGAQACLALREEGIQVILVNNNPATVMTDEACADVVYFEPLTVASVKNIIERERPDGLLATLGGQTGLNLAMKLEEAGILEAYNVELLGTPMESIKKGEDREAFRQLMHELHEPVPESEIVHSVAEAVDFANTVGYPIIVRPAYTLGGAGGGIAESEEALIRIVKGGLELSPIQQCLIEKSIAGFKEIEYEVMRDSNDTCITVCNMENIDPVGVHTGDSIVVAPSQTLTDQEYQMLRSASLKIIRTLGIVGGCNIQFALDPDSKQYYLIEVNPRVSRSSALASKATGYPIARMAAKLSLGYGLHELKNPVTEDTYASFEPSLDYVVVKFPRWPFDKLVHVNRELGTQMKATGEVMAIERNLEAGLQKAVRSLEIKTHGLSLPSLSQWEDSELWVIVKKADDRRFFAILELLRRGVTIEAIHEQTKIDRFFLTSFAKLMTLEKEIAGQSLDDITSDELSTYKKYGFSDEWLASSWGVGLADVRHTRKALGVVPSYKMVDTCAAEFEAKTPYYYSSWTGENDLLLPEKAKERVLIIGSGPIRIGQGIEFDYCSVHGAKSLRARNFEAIIINNNPETVSTDYETADRLYFEPLAVEDVLNVIEVENVDHVIVQLGGQTAIGLTKGLEEAGVSILGTTQDVIDQLEDRERFYEFMRSVEVPHIPGKTAETKEELLKAAQSIGYPILLRPSYVIGGQGMFIASNQEELAAFCEDKNHSVTFPILVDAYYPGVEFEVDVLTDGSDIFIPGMFEHVEKAGVHSGDSMAVTPPPTLEAKWKQQAINYTRQIAKGMAYKGLFNIQFVLYDEELYVIEVNPRASRTVPIFSKATSLPLITYTIDVLFGKTIAELGLSAGYRKESPYYTVKAPVFSYQKLAGLDPLLEAEMKSTGELIAISKDLPSAFRKAFAWGEEQTPALFRKKGSVFCQVDRAYDTEWQPLLRQLKEKGYSVVTEEAMSFSEWLASEDAICLVSVPAPGQKTGKQNREEALKQRVTVVSDLATFEKMIECLEVKDGEPFLLPDVVMN
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PPIA_PARPR
Sequence: MANVFFDVQFGGDAPKKIVFKLYDDVVPKTAANFRELATGSRGFGYKGSVFHRVITDFMAQGGDFTNFNGTGGKSIYGEKFADENFKLKHTKPALLSMANAGPNTNGSQFFITFVPCPWLDGKHVVFGEVVDGFDTLELFKKNSSQQGKPKTTIKIVDSGVV
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Cyclophilin, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
Protein: MNTP_YERPA
Sequence: MNLSATIILAFAMSMDAFAASIGKGATLYKPRFREALRTGLIFGVIEAITPLIGWCIGLFASQYIMEWDHWIAFSLLFILGCRMIFEGMKQRVAETEKMRSHSFWVLVTTAIATSLDAMAIGVGLAFLQVDIVHTAMAIGLATMIMATLGMLIGRYIGPLLGKRAEIIGGIVLIGIGFNILYEHMHLTA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESP4_ZOOVI
Sequence: MIAVLLLVFGMTPDYIFPVSADIPVVPNFDAQKTVGKWHPIGMASKLPEVPEYEQKISPMDHMVELTDGDMKLTANYMDGVCKEATAMLKHTDKPGVFKFTGGEIRMMDIDYEKYLIMYMKKSTFEAMYLSARGSDVGDDIKEKFKKLVLEQNFPEAHIKYFNAEQCTPTAA
What is the function of this protein?
Could transport small hydrophobic molecules into the epididymal fluid during the sperm maturation.  Binds to the head region of spermatozoa and plays a key role in sperm maturation.
What are the official names of this protein?
Epididymal secretory protein 4, C731, Epididymal secretory protein IV, LESP IV.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CMOA_RUTMC
Sequence: MRDNIFTKENDLVNFAFDSQVANVFDDMVKRSVPAYQSMIEMISLSVKTYGQDNTNYYDLGASTGATSIALGINNPHSNNQIIALDNSPDMVKKCQQNLAGKIDNVDVICGDILDMKFENASIIVLNLTLQFIAPNNRQALINRIYKDLNTNGALIISEKIHFNDQQKQKQIAKLHLNFKRANGYSELEITNKRQSIENVLITDSKQTHFKRFNMAGFKNSICHFQCLNFVSFLAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: GBRAP_MOUSE
Sequence: MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
What is the function of this protein?
Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.  Involved in autophagy: while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.  Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.  Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction.  Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation.  Involved in apoptosis.
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Cytoplasmic vesicle. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (PubMed:10899939). Localizes also to discrete punctae along the ciliary axoneme (PubMed:24089209).
Protein: KDSB_ACTP7
Sequence: MNFTVIIPARYASSRLPRKPLLDIAGKPMIQHVWEKAQQAGATRVIIATDHPEIEATAKAFGAEVCMTSDQHNSGTERLAEVIEKMQIADNEIIVNVQGDEPLIPPVIVSQVAENLDRCQVNMATLAVKLTTKEELFNPNAVKALADKNGMALYFSRAPIPFARDHFADCDDAFVASQNYLRHIGIYAYRAGFVKQYVAWQPTQLEQLESLEQLRALWYGEKIHIELAKQAPQVGVDTQEDLERVRRILA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT02_ASHGO
Sequence: MGFRFPVKTKLPPGFINARVLKDSFKRQQAADHEVTVTALKYIARNTALPTRARMEAQLQLAVMPNYTRMTQVRNRCIATGHARSVITDFRLCRTQFREKAKNGELPGVKKGVW
What are the official names of this protein?
37S ribosomal protein MRP2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CLPP_RICBR
Sequence: MRATPPRDDTYPSNENFKEKYPMSYVPIVIEQTSRGERAYDIYSRLLKERIIFVCGPIEDHMANLITAQLLFLEAENPEKDIYMYINSPGGVVTAGLAIYDTMQYIKPKVATLCIGQACSMGSFLLCGGEKGMRYSLPHSRVMIHQPSGGYRGQATDIEIHAQETLKIKKILNSLYSKHTGQDVKHVEKSMERDNFMSPEEAKKFGIIDKIITHRDIKLLKDKEQGQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CYAP4
Sequence: MPLSLYNTLTRHQEPFEPLEPGHVKMYCCGVTVYDYCHLGHARSYIVWDVVRRYLQWSGYQVRYVQNFTDIDDKILNRARQENSTMQAVSDRFIQAYHEDMQRLNILLADVYPKATDVIPEIIQLIQTLVDQGYAYAVDGDVYYAVDRFPDYGKLSGRQLEQMQAGASGRVDDTEPKKRHPLDFALWKAAKSEELSVYQPWDSPWGKGRPGWHIECSAMVRKELGHTIDIHCGGMDLIFPHHENEIAQSEAATRADLAHYWLHNGFVNIQGEKMSKSLGNFKTIRAFLNSGVDPMMLRLFVLQAHYRKPIDFSDETITAAQHSWQTLQEGLRFGYDYGQQLRWEDYQDSSFGDPACMRIPDSGAEIERFRAAMDDDLNTASAIAVLFELAKELRREGNLISHAGQPQLDPQELRSIWQTLVCLAQVLGLEVSPETEVTADDGLSEAEIEDLIQQRQAARKAKNYAEGDRIRNELKTKGITLIDQKDGSTKWIRD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3K_DROPS
Sequence: MSHLVKMENGQSQTIQEMLGCIERYNPDHLKTLEAYIQDQAKNNTYDLEANLAVLKLYQFNPHMLNFEITYTILLKSLTNLPHTDFVMAKCLLLPQQMKDENIQTIIDLADILERADFTLFWQRAEVNRTMFRHISGFHDSIRKFVSHVVSITFQTIKKDLLKELLGGIEDSTLESWIKRNGWKHQGQDLIVVAMQDDKIKTKNITEKIEFENVGALMAQCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC3_ORYSJ
Sequence: MAGATAATPMDIDAAAPPPGAAAKGKAPLSSTPGGRAAPWVEKYRPQSLGDVAAHRDIVDTIDRLTNENRLPHLLLYGPPGTGKTSTILAVARKLYGSQYGNMILELNASDERGIDVVRQQIQDFASARSLSFGAKQSVKMVLLDEADAMTKDAQFALRRVIEKHTRSTRFALICNHVNKIIPALQSRCTRFRFAPLDGTHVRERLKHIIQSEGLDVDDGGLTALVRLSNGDMRKALNILQSTHMASKQITEEAVYLCTGNPMPKDIEQIAYWLLNESFSTSFKCISDMKMRKGLALVDIIREVTMFVFKIQMPSDVRIKLINDLADIEYRLSFACNDKLQLGALISTFTGARTAMVAAAH
What is the function of this protein?
May be involved in DNA replication and thus regulate cell proliferation.
What are the official names of this protein?
Replication factor C subunit 3, OsRFC3, Activator 1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGB_BURTA
Sequence: MTGIGARTAWRNAVGRRPRNARRVSRIAYRVSRVACRVSRIAYRVSRIAYRVSRVAWRNVAPAARRAHRPFPAVIHIASGIPLPTEPLPAPPVVVDRPASPDDAALIAPDDLARLLRGEHDDPFAVLGIHAESSARDVVVRCLLPGAARVELIDAASARTLATLSPVGSGELHAIRLPAPGPLRYRLRAHYADTVRDLDDPYACTPWLGSLDCHLLARGEHRDAYRRLGAHPCVHDGLEGTAFALWAPNASCVSVVGSFNGWDARVHAMRKRIECGVWELFVPGVGCGALYKFALRTRDGDRLLKADPYARRTEAPPRTASRICAPSAFGWRDDAWMRERAAAQSAHAPIAIYEVHLDSWRRHPDGRAYSYDELADALIPYVAALGFTHVELLPIAEYPFAGSWGYQPVSLFAPSARWGEPDALRRFVERCHLAGLGVLLDWVPAHFPQDAHGLARFDGTHLYEHEDRRVGLHRGWNTLVYNLGRHEVANFLIANALYWLREFHFDGLRVDAVASMLYLDYDRDDGQWLPNVHGGRENLEAVAFLRRLNETVHADAPQGAITIAEESTAWPMVSAPVAAGGLGFDFKWNMGWMNDTLSFMRVDPIHRRFHLDRLTFGLLYAWSEQFVLALSHDEVVHAKGSLLAKMPGDAWQRHANLRLYLAFQYAHPGKKLLFMGSEFGQEREWNHDRELDWARLADPASAGVRRLVGDLNRLYRRRGCLHRRDADSRGFRWIDCADSHQTVIAWRRIGDAPDDFVVVVCNFTPQPRTGYRIGVPAAGFYRELLNSDAADYGGSGLGNLGGVSSEPVPMHGEPHSLSLLLPPLAALVFAAPGH
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: COX2_BACSU
Sequence: MVKHWRLILLLALVPLLLSGCGKPFLSTLKPAGEVADKQYDLTVLSTLIMVVVVAVVSVIFFYVIVRFRRSRVGENTIPKQVEGNKFLEITWTVIPILLLIILVIPVVLYTLELADTSPMDKKGRKAEDALVVNVRANLYWWEFEYPDYGIITSQELIVPTDQRVYFNLKASDVKHSFWIPSVGGKLDTNTDNENKFFLTFDSKRSKEAGDMFFGKCAELCGPSHALMDFKVKTMSAKEFQGWTKEMKNYKSTAESDLAKQGEELFKEKNCLSCHAVEPNDKRAEAARTAPNLATFGERTKVAGVKEANKENVKAWLKDPDSIKPGNKMTGTYPKLSDSETNALYEYLKGLKAESK
What is the function of this protein?
Subunits I and II form the functional core of the enzyme complex.  Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Caa-3605 subunit 2, Cytochrome aa3 subunit 2, Cytochrome c oxidase polypeptide II, Oxidase aa(3) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_YERPY
Sequence: MPKIKTVRGAAKRFKKTANGGFKRKHANLRHILTKKATKRKRHLRPKGLVSKNDLGLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RF1_MESHJ
Sequence: MEKKMFNSLMKIHQKYQDLKQLLETDQILNDQKQYLQIAKEIASISEIIEVFQKFLDDQKVLEDAKTILIQEDDPELIQLAKVEIATMSKNIEEYEKKLLILMLPKDKNDEKDVIVEIRGAAGGDEANIFVGDLFKMYHKWADSQKAKVKVLSSSLALAGGFSQIIFQISGQKIYSKLKFESGVHRVQRVPATETMGRIHTSTATVTVMPKIDEKIEIEINPSDLKIDTYRSSGAGGQSVNTTDSAVRITHIPTGIVVTSQDERSQIGNKEIAMGILKSKIYNLELQKQQQKQSDFRKLAGSGARSEKIRTYNYPQDRLTDHRINFSTSLKPIIQGSLNPIIEALLAQEKTELILQNYANK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_HALHL
Sequence: MNHPAARLDARLAPRLAERRQAGLYRCAEALEDYDGATAVRSDGQRCTVFCGNDYLGLAADPRPARALAEHARRQGSGAGAAHLVTGHRPEHEALEAELAAFTGREAALLFSTGYMANLGVVTTLVRRGQAVAEDRLNHASLIDAVRLAGGRPRRYRHADPTHLAQRLDDRAQLVVTDGVFSMDGDVAPLPELAAAAEATGAALVVDDAHGLGVIGPEGGGSVPATGCAPERVPVLVGTLGKAFGTFGAFVAGSRTLIDALRQWARPYIYTTAPPPAQAAAALEAVRIARAEGWRREHLQALIARFRSGARQLGLPVPQPAGPRTPIQPVLVGPSATATAWSAELDRRGLRVAAIRPPTVPAGTARLRVSLTACHSEEDVDRLLEALAAAARQAPPTLEAPS
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: H2A3_RAT
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 3, H2A-clustered histone 25, Histone cluster 3, H2a.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SNOAB_STRNO
Sequence: MPTRVNDGVDADEVTFVNRFTVHGGPAEFESVFARTAAFFARQPGFVRHTLLRERDKDNSYVNIAVWTDHDAFRRALAQPGFLPHATALRALSTSEHGLFTARQTLPEGGDTTGSGHR
What is the function of this protein?
Involved in the biosynthesis of the anthracycline (aromatic polyketide) antibiotic nogalamycin (PubMed:8760909, PubMed:8668120).  Catalyzes the oxygenation of 12-deoxy-nogalonic acid at position 12 to yield nogalonic acid (PubMed:19255477, PubMed:20052967).
What are the official names of this protein?
Deoxynogalonate monooxygenase, 12-deoxy-nogalonic acid oxygenase, Cofactor-independent monooxygenase SnoaB.
Protein: HEXB_STRPN
Sequence: MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKYMKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPDALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLTLFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  The hex system is nick-directed.
What are the official names of this protein?
DNA mismatch repair protein HexB.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: TSAC_BUCAP
Sequence: MSKDYFLSSLIKCIRKLYDKKIIAYPTEAMFGLGCDPTSEKAVKRLLDLKKRSIKKGLILVASNYNQIKMYINESKLSAQQKKTMFFHWPGPYTFLVPANSLVPCWLTGQFDTIAVRISAHFSIIKLCNVFGKALVSTSANISNMSPCLTREDVLKDFGKDFPVLYGHIGNESHPSKIINIVNGKLIRYV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOG1_COCHE
Sequence: MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSAKDQLTNQAVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVQSLPKRERQPLANKFKNAEPDAVDLLENMLVFDPRKRVRAEQALAHPYLAPYHDPTDEPVADEKFDWSFNDADLPVDTWKIMMYSEILDYHNVDAAVPEQENNGS
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FABZ_HAEIE
Sequence: MSEQQPRVIESKEIMTLLPHRYPFLLVDRVLDFKEGEWLKAIKNISVNEPCFTGHFPGEPILPGVLILEALAQAMGILAFKTLELKGGELFYFAGIDEARFKRPVLPGDQMELNVQVIKERRGITAFTGVATVNGEIACEAKLMCARR
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.