PharMolix/UniProtQA huggingface dataset:
Protein: FSA4_FUSSF
Sequence: MSSILSRYPEAETPVHGYFYSMVELAVVRVFVQHQIFDAIADDGTSIEELATKTGMELNLLERLSNFLVASKVLSSPKPGFIGLPSETKMFQQRRAKLFYSHIFDAFMGSAVKWPQYLQNNGLAEPQKSNRSPFGLGAGYPDKSFYDVLEMMPERAQAFNSTMAIGLGDMPITGIYDFSWVAAHSGTDPERTLIVDVGGGKGQAIKAIVEETPSIPASACVLQDLPNVIKDVPEEEGILNQVQKVGSSFFDKQPTKGALVYYIRRVLNDWPDDECVTILKNIREACASDSRLLISENLLPDEPSVSLAAADLWMMNFAGKRRNVRMFNDLASRSGFEISSIAKDKTSNSAVIEMLPVQI
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of HIV-1 integrase inhibitor equisetin and of fusarisetin A, both trans-fused decalin-containing tetramic acids showing also antimicrobial activity (PubMed:25770422).  The PKS module of fsa1 together with the enoylreductase fsa3 catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the fsa1 NRPS module (PubMed:25770422).  Activity of the Dieckmann cyclase domain (RED) results in release of the Dieckmann product intermediate (PubMed:25770422).  Diels-Alderase fsa2 is involved in endo-selective Diels-Alder cycloaddition to form the decalin ring, leading to the production of N-desmethylequisetin also called trichosetin (PubMed:25770422, PubMed:28401214, PubMed:29972614, PubMed:34121297).  Subsequent N-methylation is carried out by fsa4 to give equisetin (PubMed:25770422).  The enzymatic gene responsible for the conversion of equisetin to fusarisetin A has not been identified yet and is probably located outside of the fsa cluster (PubMed:28401214).
What are the official names of this protein?
Methyltransferase fsa4, Fusarisetin A biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: RPOC_SHEFN
Sequence: MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTTLERGQMLTEETYLDALEEYGDEFEAKMGAEAVLELLRAINLAEQIEQMREELPSINSETRRKKVTKRLKLMEAFFTSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEARGLATTIKAAKKMVEREQAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRECINGRGEGMAFADVSEVEKAYATGVAELHARVKVRITETNIADDGERTKSTRIIDTTVGRALLSLILPEGLSYDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVGIDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVPEQQASFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGVEHGLTMKPLIEGGDVVEPLRERVLGRVVALDVMKPGTNEVLAPRNTLLDEAWCNTLEEHSIDEVIVRSVITCDTDFGVCAACYGRDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNAGSLKLHNAKHVSNIDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEDSEVAAGEIIANWDPHTHPIISEVAGSVKFVDMIDGVTMTRQTDELTGLSSVVVLDVGARTSAGKELRPAIRLVDADGNDLMIPGTEVPAQYFLPGNAIVSKDDNAKINVGDPLARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGSEHYEEMIPKWRNLNVFEGEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCLITSTGDTEFLEGEQAEVSRVKIANRELIAQGKTPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDPLRGLKENVIVGRLIPAGTGYAYHKTRNEERAKILSSRGKVETTTVTASEAEKNLADLLNLAGSQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NUP3_PENSQ
Sequence: WGALGHATVAYVAQHYVSPEAASWAQGILGSSSSSYLASIASWADEYRLTSAGKWSASLHFIDAEDNPPTNCNVDYERDCGSSGCSISAIANYTQRVSDSSLSSENHAEALRFLVHFIGDMTQPLHDEAYAVGGNKINVTFDGYHDNLHSDWDTYMPQKLIGGHALSDAESWAKTLVQNIESGNYTAQATGWIKGDNISEPITTATRWASDANALVCTVVMPHGAAALQTGDLYPTYYDSVIDTIELQIAKGGYRLANWINEIHGSEIAK
What is the function of this protein?
Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.
What are the official names of this protein?
Nuclease PA3, Deoxyribonuclease PA3, Endonuclease PA3.
What is the protein family that this protein belongs to?
Belongs to the nuclease type I family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSCB_ECO27
Sequence: MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: RL2_KOCRD
Sequence: MAIRKHKPTTPGRRGSSVADFVEITRTTPEKSLVRPLPKKGGRNNTGRITTRHKGGGHKRQYRVIDFRRHDKDGVDAKVAHIEYDPNRTARIALLHYVDGTKRYIIAPNRLQQGDVVESGPNADIKPGNNLPLRNIPVGTVLHAVELRPGGGAKLARSAGASVQLVAREGKYGQLRLPSGEIRNVDVRCRATIGEVGNAEQSNINWGKAGRNRWKGVRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVNPNGKPEGRTRRPNKESDKLIVRRRRTGKNKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSAD_CUCSA
Sequence: MAMATQATLFTPSLSTPKSTGISIPWKQSSTLSFLTSKPHLKAASSSRSFKVSAEAETSVEAPAGFSPPELDPSTPSPIFAGSTGGLLRKAQVEEFYVITWESPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKIKYQFYRVFPNGEVQYLHPKDGVYPEKVNPGREGVGQNFRSIGKNVSPIEVKFTGKQVYDL
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein.
What are the official names of this protein?
Photosystem I reaction center subunit II, chloroplastic, PS I subunit 5, Photosystem I 20 kDa subunit, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: YDDG_BACSU
Sequence: MVVMKKKRILIVSAIVLLFLTVASAVTVFSADGDTTTQPKVEKAGGVELKVKRFPISRYQANNEASDDLIKGAFVGLTNVTFSFAGNIVRVVDTGMDILYNLQPIDEFANSITNVSKTVYKTLKKNFGEALFIFTCAYVVYLFCVRGSVKEAMRRSILFICVMVIGGLWMSNAGYYMKVLNALSVEAQGKLLTAGNGLVGIVQDEGNFADSSAIEKGKEMEGTVAVMRNLYFDIALMKPFLIVNFDETSEKKINEEDTDKGGLNRIDKLLSYKLSEDGEKDKKDYIKETEIDDYKNESMTSGNVFNQLGESFIAVVASIVIGIPFLALAFFNFLLQVVALVIVFFVPFAFILAYVPQLAYSGFVTLGRLGSVYLLKAMLGVIVLFVYVTCFIVDKLIPPNGFGMYLLNVAVLASILWIGFHKRDAIIKFVTAGKVVSVDNNMMENMRQNIVQPAWEQAKKIGGVWGNGGGVFTDFTKHFGGRKDGSNADGVTGAPSGGGNSPSGTAMGYDNTHAISRTPQKETANGIANHNSRSLKRNPQTLSKEQEKQKQKEAFANAKENKQQSHLARLRKDGINSPMLKDALNEGNEDLSKRAPILQDKKDESARTDQKEYVEQLLKQPNNQQQTDDASLQHEEESTSNRAPVLQENEKDTERTDQKAYIYDEQNQNLETDQQQDFEVQKDDSVSNSEPVAQEKTAEIKRSDQKVMMNQPEPQLGFESPQSTKVENQPIANNERKIRPSEPAKVHSDGIRVDEKQAVAPAENKTVSREKQPSSQTIKRTEQSVNSFDQVSLNEIARRSSSKVEDRLRRDERTR
What are the official names of this protein?
Uncharacterized membrane protein YddG.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERV1_YEAST
Sequence: MKAIDKMTDNPPQEGLSGRKIIYDEDGKPCRSCNTLLDFQYVTGKISNGLKNLSSNGKLAGTGALTGEASELMPGSRTYRKVDPPDVEQLGRSSWTLLHSVAASYPAQPTDQQKGEMKQFLNIFSHIYPCNWCAKDFEKYIRENAPQVESREELGRWMCEAHNKVNKKLRKPKFDCNFWEKRWKDGWDE
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.  Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (IMS).  Forms a redox cycle with MIA40 that involves a disulfide relay system.  Important for maintaining the cysteine residues in MIA40 in an oxidized state.  Reduced ERV1 is reoxidized by cytochrome c.  Required for the maturation of cytoplasmic, but not of mitochondrial Fe/S proteins.
What are the official names of this protein?
Mitochondrial FAD-linked sulfhydryl oxidase ERV1, 14 kDa regulatory protein, Essential for respiration and vegetative growth protein 1.
Protein: VMA21_SCLS1
Sequence: MATQRRSHNDRIAAGEEKEASFKAEAVLGEKSNIAPAVPAHIIYKLLGFTLAMIIIPISSYFLTLNSIFRGNSTFAGATAAIMANVVLVGYVIVAMKEDQSEALEAAAAKETKTESKKEL
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: STLP4_EMEVA
Sequence: MEGSINDARRTNYLVLLRTCYEIYGIYEPLLALFAVYSVAVVVYRLYLHPLARFPGPKLAAATGWYEFYHDVFRGGQYLYEIESMHRKYGPIIRINPHELVVNDPDFYNTVFVAANTRRTDKWSGLEGIGLRGSLAFTRDHDLHRIRRKRYEPFFSRLSVSRIEPIIVDEAKLLAKQLEASSKTGRVIELEHVMSAFTGDVITTLCSEKSPDMIRHPEFGKGWHTSLYNFPSCFRAGAFNSFLEYSTDHINTAKREMLSVDKLEQNNKSSVFRYVLSTDMPQAERDTERLAREAALLFGAGSVTTTRFFSVTIYYTLRNRQIRDRLSAELKDVMAGYPSTLPTWQELDRLPYLHAIVKEGLRYACPFVLSSSLAAWSSLSHKFSSRLSYGVMRHLSRISPDSALHYKQWTIPPGTPVGMSSYSLHTDPETFPEPFKFMPERWLGEYNPKMNRSWVPFTRGSRNCLGMNLAYAQIYWGLAVMFRPGGPRLELYETNESDIRPVLDFLGPLPKSGSRGLRVTVS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the sesterterpene stellatic acid (PubMed:26351860).  The first step in the pathway is performed by the stellatatriene synthase that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) and then converting GGDP into stellata-2,6,19-triene (PubMed:26351860).  The cytochrome P450 monooxygenase Stl-P450 then catalyzes three successive oxidation reactions on the C-20 methyl group to generate the carboxylic acid of stellatic acid (PubMed:26351860).
What are the official names of this protein?
Stellatic acid synthase, Cytochrome P450 monooxygenase Stl-P450, Stellatic acid biosynthetis gene clusters protein Stl-P450.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PUR5_STRA3
Sequence: MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSQTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGDEVLPELEGKQLKDVLLEPTRIYVKAALPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADASVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2311_MYCTO
Sequence: MAPTGQAVDVAVREGAGDVGYSVERENLPADDPVRNGNRWRVIAVDTEHHRIAARRLGDGARAAFSGDYLHEHITHGYAITVHASQGTTAHSTHAVLGDNTSRATLYVAMTPARESNTAYLCERTAGEGARVDLAGWDLWVSGKAEAMSDEKSASPVWCRVGARCDHRGKRSCW
What are the official names of this protein?
Uncharacterized protein MT2373.
Protein: MAP2_YEAS2
Sequence: MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIELLFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_HPV19
Sequence: MTPVVIFTYIPAFASDSNENVNIYNFLLQMAVWQAASGKVYLPPSTPVARVQSTDEYVQRTNIYYHAYSDRLLTVGHPYFNVYNVAGSKLEIPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWGCRGIEIGRGQPLGVGSVGHPLFNKVGDTENPNSYKGTSTDDRQNVSFDPKQLQMFIIGCAPCIGEHWDKALPCAEQDIPQGSCPPIELINSVIEDGDMADIGYGNLNFKALQQNRSDVSLDIVNETCKYPDFLKMQNDVYGDSCFFYARREQCYARHFFVRGGKTGDDIPAGQIDEGSMKNTYYIPPNNSQQQYTNLGNAMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGICWFNQLFVTVVDNTRNTNFSISVNSDGTDVAKIADYNSANFKEYLRHVEEYEISLILQLCKIPLKAEVLAQINAMNSNILEEWQLGFVPAPDNPIQDTYRYIDSLATRCPDKNPPKEKVDPYKNLHFWNVDLSERLSLDLDQYALGRKFLFQAGLQQATVNGTKTISSRVSSRGTKRKRKN
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DCUP_TROWT
Sequence: MTGASGVEGTRIPLHSLSCRPSAGRSAGSFVNTGIMEAFRGTRPGCLPVWFMRQAGRSLPEYRAVRGTNTLLEACLNPDLACEITLQPVRRYSVDAAILFSDIVVPLKLAGVGVDILPGTGPVLNNPIDTPDRVNTLLAKTADSIDFGIIAEITRHTVSVLNGIPLIGFAGAPYTLACYMVEGGPSKTHMKARAMMHGDKKTWQKVMMLAARLSGQFLAAQITSGAQAVQIFDSWAGSLSRKDYVDNVAPFSKMTIDLACGIDGNSDLSKTGKSLWPRVPVLHFAANAGHLLTAIRDIGVSVMSVDYTKPLDEASELLDDSMPLQGNIDPAMLFAPWEVLKRHVLDIVQRASRAPSHVLNLGHGVPPDASCDQLARIVDLAHSMV
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_EHRCR
Sequence: MREGKRKNMSNKKVLTGIVVDAKCDKTIKVMVSRMIMHKTYKKIVKKRKNYVVHDEHNQYKCGDVVKIQEHIPISATKRWIVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: URE3_LACP7
Sequence: MMLSPREQEKLLIVVAANLARSRKERGLKLNYPEAISMIAFEILEGARDGKSVSELMQAGREVLTVDDVMDGIADMIHDVQVEATFPDGTKLVTVHQPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_GLUDA
Sequence: MKLLHLDASILPEDSSVSRTLSAAVVAHVRALQPDLTVTRRDLVAHPLSHMTLANLPPDHPASVPGNEVERAESQAVLEEFLTADIVVIGAPMYNFTIPTQLKSWLDRVLVPGRTFKYGPEGVKGLVEGKRVIVALSRGSFYGQETPYATAEHTETYLRTALGFIGIATPEVIVAEGVSRGEDQRAAAIEAAHQTVAALRV
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: YCP1_STRLI
Sequence: MTAGPHRVVVLVFDGMKLLDLSGPAEVFSEANRFGADYRLSIVSADGSPVRSSIGMLVPADTDARAAAAHDTLVVVGGDALPGSPVGPVLGAAAKELAERAGRVASVCTGAFVLGAAGLLEGRRATTHWQHTATLARRCPS
What are the official names of this protein?
Uncharacterized protein in cpoL 5'region, ORF1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RL14_POLSJ
Sequence: MIQTQSKLDVADNTGAKSVMCIKVLGGSKRRYASVGDVIKVSIKEAAPRGRVKKGEVYSAVVVRTAKGIRRGDGSLVKFDGNAAVLLNAKLEPIGTRIFGPVTRELRTEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RF3_ALIF1
Sequence: MSFLQEVGKRRTFAIISHPDAGKTTITEKVLLFGNAIQKAGTVKGRGSNQHAKSDWMEMEKERGISVTTSVMQFPFNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDREVRDPMEVLDEVESELGMACAPISWPIGCGKEFKGVYHIHRDETILYESGHGHEIQEVRTIKGLDNPELDATVGADLAESVREELELVMGACPEFDHELFLAGELTPVYFGTALGNFGVDHMLEGLTDWAPAPQTRQANERDVVATEDKFSGFVFKIQANMDPKHRDRIAFMRIVSGTYTQGMKMNHVRTGKNVSISDAVTFMAGDRSRAETAYAGDIIGLHNHGTIQIGDTFTQGESLKFSGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVARLKAEYNVEAIYEGVSVATARWVDCADGKKMDEFQRKNQANLALDGGDNLTYIAPTMVNLNLASERFPDVQFRATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM5_YEASL
Sequence: MTVITIAKRGLPKLTTSTSSTTTASSSSTITSVXSSSSSLPLLSNSTSSSIIPSITPPSRNGNPYILDSGDMPNGTVFIVVGGIAGVIFLAILLWWVITTYSSHRLTRSVQDYESKMFSXQHTQFYGDSPYMDYPAKENFQDQVHISESDISPGNKDESVKDALVSHTNNEKPFLSNFERPLSSLVSESNRNSLFISPTGDILYKTRLSKLYQESPRLLQKPVIMTSDNVSTNSLVSTISSSSASSLDNGNEKEVGEDIRKPAKIASSPSRKLLNSPESDGSVNRNHSKGNLLVVQSKRKPTPSTYLEHMLEGKEQDE
What are the official names of this protein?
Pheromone-regulated membrane protein 5.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: POTA_SALTY
Sequence: MGQSKKLNNQPRSLSPLVLLSGISKSFDGKEVISQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDAGHIMLDNQDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEIAPRVTDALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRNGVIEQDGTPREIYEEPKNLFVAGFIGEINRFDATVIERLDEQRVRASVEGRECNIYVNFAVEPGQKLNVLLRPEDLRVEEINDDNHIEGLIGYVRERNYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAISWVESWEVVLADEEHK
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPG_HELHP
Sequence: MGGNLKNIKRQISSTKNTQKTTKAMKLVSSSKLKKAEELARRSKVYAKQLSAVFHDVVAKIRVRGLDNINSRYFAKSEGREIKKLDIIFITADKGLCGGFNITTIKEVLRLMETYKQQGIKVRLRGIGKTGISFFAFNDIEVLDKAIGLSAAPTFEKAEAFIENVVEDFLNGATDEVIIVHNGFKNMISQELESQAILPLTINIKQNEQPSVLNIEPEDEENIILDELAKKYVQYNMYYALVDSLAAEHSARIQAMDAATNNAGDLVKSLTISLNKARQEAITTELVEINAGAEAIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRUA_PROMA
Sequence: MATTKGFDCNKESKIKRIALSIQYQGSNFSGWQRQKVGHTIQAILEDAIFSLDSSKPAKVVAAGRTDAGVHAAGQVVHFDSFGPIPVHRWPSALNGRLPEAIRVRDSVEQSLDWHACHSAVYRRYRYIIYNGCTPNLFLNPWTWHKYQYQLDEELMEEAAKGLIGMHDFSAFQRSGSNRTHAFTTIQEVKLVRHGDLLVFDIQASGFLYGMVRLLVGQLVSIGEHRLSINDFETRWKLKLRSEVKEAAPARGLCFIRAGYKESIFRENIVFDSFPGFLLLTNDPPERII
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: SYM_MARN8
Sequence: MTQASKQQRDILVTSALPYANGPIHLGHLLEYIQTDIWVRFQNMRGHNCYYVCADDAHGTAIMLRAEREGITPEQLIDRIRQEHQEDFAGFHIRFDNYYSTHSEENQYFSEYIYRQLKDNDHIATRKITQFFDPEKEMFLADRFIKGTCPKCKTEDQYGDNCEACGATYTPAELINPRSAVSGATPVEKESEHYFFKLPEFHDFLSKWTRSGALQPQVANKLAEWLDAGLQEWDISRDAPYFGFEIPDAPGKYFYVWLDAPIGYLASFKNLCNREGIDFEHFWKKDSSAEVYHFIGKDIINFHALFWPSMLHDAGFRTPTAVWAHGFVTVNGKKMSKSRGTFIMARTYLDHLDPEYLRYYFAAKLTGGVDDMDLNLDDFAARVNSDLVGKVVNIASRSAGFITKRFDGKLGKVTEQDKLKEFIDAGEQIAEFYEAREFGRAMRRIMELADIANQYVNDEQPWVIAKQEGQDDKLQAICTNALNMFRLLMTYLAPVLPKTADAAQSFLNSRLDWNNRAALLENHGIDKFKPLMNRVDMAQIEKMLDASKEEMPAAVGQPSAAPTADLEPVAEEIEFPDFAKVDLRVAKIVKAEHVEGADKLLRLTLDIGHGERNVFAGIKSAYKPEDLEGRMTVMVANLKPRKMKFGMSEGMVLAAGPGGKEIFILSPDSGATPGMRVM
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LACLA
Sequence: MLTKRIIPCLDIKNGKVVKGINFVGLREIGDPVELAKIYEEQCADEIVFLDITASFEEREIIGELIGRAARELSIPLTVGGGIRSIDDFRRILARGADKVSVNSAAIENPELIRQAANEFGVQCVVVAIDAKKRADHRGYDVYIKGGRENAGLDLVDWAKKCERLGAGEILLTSMDKDGTKTGYDLEMLNDVCTAVNIPVVASGGCGKISDIVEVFQNTRSDAALFASLFHYGEATVDEVKDELIKNNIPARIIKKETL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.