PharMolix/UniProtQA huggingface dataset:
Protein: MDH_METMP
Sequence: MDVSIIGASGKIGSVLSLLLAKESHIKNINLIARSSSINKLKGLKMDLYDAMAAAGQDTDIDICCDDDLSCTANSDITIITAGMARTGEMSRIDLMKGNAKIVKNYVKNIANFGDTKIFMISNPVDLMTYKALIESGYEKNQVFGLGTHLDSMRFKVAVAKHFEVHLDDVRTRIVGEHGDSMVPVISATAVGGIPIKRLPKYEDFPYEKILERIKGYGQEIINLKNGSEYGPASAIVNIVRCIAHDEKRLLTLSTYIEDEIEGIEGGCCIGVPVKVGKNGIEEVIHIKMEDDEIEGFKKSFELVKGYCRQIESI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: RIR2_ENCCU
Sequence: MSHGEETELLLDPKEERFVLLPIKYHDIWKMYKKAESSFWTVEEVSLDKDIDDWGKLNAKERHFISYVLAFFAASDGIVNLNLVERFSTEVKVLEARFFYGFQMAIENIHSEMYSLLIDTYIRDNDEKNFLFDAIRTIPSVKEKADWAIRWIEDKNSDFATRLVAFACVEGIFFSGAFASIFWLKKRGLMPGLTFSNELISRDEGLHCEFACLLHYHLKKKCNRIKEVVMDAVEIEKKFLSESLPVNLIGMNCNLMCRYIEFVADRLLENLGEERVYNATNPFDFMENISLVGKTNFFDKRESQYQKAFVGIENGNDSFRIDVDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: RLMD_AROAE
Sequence: MPVAVIESLDHEGRGVAHVDGKVVFVEGALAGEQVEYTVYRQRPSYDLAEATRIIKASAQRVRPRCEHFGVCGGCSMQHLDSVAQAAAKQRVLEDALWHVGKVRPDIIYAAIHGPSWGYRYRARIGVRVVPKKGGVLIGFHERRSSYIADMRSCPILPPHVSGMLPALHELVGGLSIADRLPQIEIAIGDTAIVLVFRNLLPLTPADEARLAAFAGEHGVQVWLQPGAPATAHPLHPKGAAPLAYTLPEFDVAMAFQPTDFTQVNIDINRLLIRRSLQLLDPRPGERIADLFCGLGNFSLPIARCGATVVGVEGSESLVRRAAKNARRNGLHGRSEFHAANLFEATEDSLAALGRLDKLLIDPPREGAIAVVKALSTLQSPARIVYVSCNPATLARDAAVLVHEKGYVLRGAGIANMFPQTSHVESIALFERN
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: ICA69_MOUSE
Sequence: MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQYRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEGKKTSWRENREAVAPEPRQLISLEDEHKDSSAYKTEEGTSVLSSVDKGSVHDTCSGPIDELLDGKPEEACLGPTAGTPEPESGDKDDLLLLNEIFSTSCLDEGEFSREWAAVFGDDQLKEPAPMGAQGEPDPKPQIGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA
What is the function of this protein?
May play a role in neurotransmitter secretion.
What are the official names of this protein?
Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Protein: HISZ_TRIV2
Sequence: MVYQPAAGARDLLPLDVAQKRWIEDKLQQVFHRWGYHRIITSTLERMDTLMAGEAIQRQMVIQLQNSEDEELGLRPELTASIARAVVTRMTNLRHPQRLYYNANVFRRIWENRHNRQQEFYQAGVELLGVGGLLANAEVLLLAGNCLTALGLQDWHLILGEAGITRSLLDAFPINLRAKVRSAIAHLDRITIDTLPLTDELRERARIMLDLRGNSTDVLQKVSSLNLDAEQQEAVNNLQSLVELLESGGKFPIILDLSLIQTIDYYTGIVFEIVNNTDSQARVLGRGGRYDQLLGLYHPQGENIPGIGFVLNIEDLYQVLLTTQQLPQETPASDWLVVPENPKAHSAAFAHAQKLRESPDLVRVELDLGGTDIPAIQQYARDRRIAQIAWIKADGSLIIEKVSQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BACFN
Sequence: MRKAKPKKRVILPDPVFNDQKVSKFVNHLMYDGKKNTSYEIFYAALETVKAKLPNEEKTALEIWKKALDNVTPQVEVKSRRVGGATFQVPTEIRPDRKESISMKNLILFARKRGGKSMADKLAAEIMDAFNEQGGAFKRKEDMHRMAEANRAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FOLD_DEIRA
Sequence: MQTSSEPAASETAALLGKPLADRVMRGVRADLKAWAQLDPPFEPQLVSVLASDDEASQVYVQSKAKRAKKLGVAFRVVDLGAAATQEALEQTLRELSADPAVHGIVLELPLAAGLDADAALLHIAARKDIEGLSPANLALIAAGREPEALLPPTPRSVRFLLRHALGDDLRGLRVAVIGPGRTVGRPLLFMLNNKGATVTLCNEHTRDLAAVLAAQDAVVVAVGKAGLLRPEQVQPEHVVIDAGINVQESGDMVGDALPELPVRAQTPVPGGVGPLTSALMYQNLVRGVKLQRGEPVDD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HIS2_CORGL
Sequence: MKTFDSLYEELLNRAQTRPEGSGTVAALDKGIHHLGKKVIEEAGEVWIAAEYETDEELAGEISQLIYWTQVIMVARGLKPEDIYKNL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SERP5
Sequence: MRVLGIETSCDETGIAVYDDQAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLTAADIDGVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEDNPPAFPFVALLVSGGHTQLISVTGIGQYQLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSKMAQQGAAGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRSNGNDDQTRADIARAFEDAVVDTLAIKCKRALEQTGFKRLVMAGGVSANRTLRTKMAEMLHKRGGEVFYARPEFCTDNGAMIAYAGLVRLQSGANPELSVSVRPRWPLAELSAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_CHLTE
Sequence: MQEASAAITAERKHSHVDICLNRPVCFDGQDTGLDSWRFEHNAAPEVDFAQIDLSTEFLGHAIGLPLMISSMTGGYGNALALNRALGEAAERFRIPLGVGSMRQALEGSSHRESFSVVRSSAPSVPIFANIGAPEVAAGLSRDQLSTLIDLIEANGLIVHLNPAQELFQPEGGTDFSGFLDRLHDITATIGVPVIAKEVGCGISATVARKLADAGVRAIDVAGAGGISWQKVEECRYLDRFGHEERFSPSALDEFLNWGIPTAECLTSIQTLKRQNPEYDALSVISSGGIRNGLDIAKSIALGANIAASAQHLLKALHSGTLEETIRTWANDLRAAMFLTGSATIEQLKHARIYRKP
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLN_PINTH
Sequence: MSTKIVETITLECETGNYHSFCPISCVSWLYQKIEDSFFLVVGTKTCGYFLQNALGVMIFAEPRYAMAELEEGDISAHLNDYEELKTLCIRIRKDRDPSVIIWIGTCTTEIIKMDLEGMAPKLEYEIGVPILVARANGLDYAFTQGEDTVLAVMAHRCPDQELPIGESKETKTKLFPFPLLKEKNLVEYANHPPLVIFGSLPSNLVSQLDTELRRQFIKVSGWLPAQRYADLPSLGDGVYVCGVNPFLSRTATTLIRRKKCELIVAPFPIGPDGTRAWIERICPVFGIEAQSLEEREERIWESLKDYLDLVRGKSVFFMGDNLIEISIARFLIRCGMIVYEIGIPYMDKRYQAAELALLQNTCIRMCMPIPRIVEKPDNSNQIRRMRELQPDLAITGMAHANPLGARGIGTKWSVEFTFAQIHGFANARDVLELVTRPLRRNENLDNLDRTTLVRKNNELYTSTPVK
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CK097_RAT
Sequence: MRRQEALVVTAGTASEASRDGEQPRPAGLVCRARVEPGGPQESRQQWKTFLYCEPHKRIKEVLEEELSIKRDECHVKSPTAVALDGIWSIRRNLPVGGMIPGQQSRNCSLPQTKYYSRHGGLRR
What are the official names of this protein?
Uncharacterized protein C11orf97 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: DNAA_METCA
Sequence: MSVLWSHCISKLEGELPPQQFNTWIRPLQAVEDGGELRLLAPNRFVLDWVKQHFIGKIEEVVSEQNRDSAPNVVLEIGSRAAEAAQMRSANPPRKTAPARKQVPNNLNSAFIFGNFVEGKSNQLAKAASLQVAQNVGRAYNPLFIYGGVGLGKTHLMHAIGNEILRGNPAANIVYLHSERFVSDMVKALQHNAINAFKEFYRTVDALLIDDIQFFAGKERSQEEFFHTFNTLLENKHQVVLTCDRYPKEIKGLEERLKSRFGWGLPVAIEPPDLETRVAILMSKAQQSGIDLSPEVAFFIGKRIRSNIRELEGALRRVIANAQFTGRPITLEFAKEALRDLIALQDRMINVENIQKTVSEYFKIRQADLLSNKRTRSLTRPRQIAMALSKELTSHSLPEIGQMFGGRDHTTVLHACRKVQELKESDARFMEDFSNLLRILSN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_METPP
Sequence: MPRVKRGVTARARHKKVLELAKGFRGRRKNVYRIAKQAVMKAGQYAYRDRRNRKRVFRRLWIARINAASRSHGITYSRFIAGIKKAAIDIDRKMLAELAVNDPAAFGSIVEKVKAQLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y190_AFV1Y
Sequence: MEKKVDKNEFLNMVLLKLEEGKVFLGKHGLKINISLDNVRINSGSVSITVGDIYLKVDMRNSELVLNDLENHEVYIYSYANDEVKIRITQNTFYLYMQIDELKPVTQEVMLRAIEALRIPFSKREGLRIDIDLTQYHEIEYTSEDGLQLRYGVDDIQIKDDKLVMNGLAIDILNNDWFISFEKNVMSMIL
What are the official names of this protein?
Uncharacterized protein ORF190.
Protein: PELO_PYRHO
Sequence: MEILEEKPKEGKVKIKVETLDDLWHLYHIITPGDVVYAKTLRKQSQRSDSLRPEKVEVIPVFLGVKVEKINFHKFANQLRVTGPIIYASREDVPLGKYHTIAVEPGTIITLQKERWKPYYIERLKEAVEASKRAKVMIVTIEDGEAEMAIVREYGLDFIATIRHNLGGKRYNIKREDEERKFFHDVAKTMKDVMSRENIQRAIVAGPGFYKEDFYKFLKENYPDLASKIVLDDTSMGGRVGIYEVIKRGTVDKVYSESRIANEIKLVEKVIERIAKDEPVAYGMKEVEEAVNYGAVEILLVLDELLKGDNREKVEELMELARSLRSKVVVVSSEHEGGEKLKALGGIAGILRFKIK
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_SHIBS
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: SYP_ALKMQ
Sequence: MRMSKLYMPTLREVPSEAELPSHQLLLRAGMIRKLVAGVYSYLPLGYRTLKKVEQIVREEMDRAGAQEALMSALQPKELWEATGRWQAIGPEMMRLKDRHNREFCLGPTHEEVITDLVKNELKSYKQLPLNLYQIQTKYRDEKRPRFGLMRSREFIMKDAYSFDKDEEGMKKSYEDMWKGYERVFDRCELKYKVVEGDAGAMGDSESHEFMAMSQYGESLVAYCDHCDYAATDEKATVVYDVTEKDEGLLETEKIHTPNTKTIEALTMLFDCDANHFIKTLLFEAGEKVVAVSIPGDRDVNETKLVNMLNIPGHELVMASEATVKRVTGAEVGFAGPMNLKGEVKLYVDARVSKMKNVVVGANETDYHIKNVNYGRDFEGELVEDLLLVQEGDLCPTCGETLKLDRGIEVGNIFQLDMKYSKGLNATFLDENGKEQYFYMGSYGIGIGRTMAAVIEQYHDEKGIKWPLALAPYQVVVTIVNPNKDEQRELGEKIYSKLLSKGVEVLLDDRKESPGVKFKDAELIGIPIRVVAGKNAGENIVEFALRATDEKKEVEADEVVEMVMDQLKGL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD4_ARATH
Sequence: MDSVSSSSFLSSTFSLHHSLLRRRSSSPTLLRINSAVVEERSPITNPSDNNDRRNKPKTLHNRTNHTLVSSPPKLRPEMTLATALFTTVEDVINTFIDPPSRPSVDPKHVLSDNFAPVLDELPPTDCEIIHGTLPLSLNGAYIRNGPNPQFLPRGPYHLFDGDGMLHAIKIHNGKATLCSRYVKTYKYNVEKQTGAPVMPNVFSGFNGVTASVARGALTAARVLTGQYNPVNGIGLANTSLAFFSNRLFALGESDLPYAVRLTESGDIETIGRYDFDGKLAMSMTAHPKTDPITGETFAFRYGPVPPFLTYFRFDSAGKKQRDVPIFSMTSPSFLHDFAITKRHAIFAEIQLGMRMNMLDLVLEGGSPVGTDNGKTPRLGVIPKYAGDESEMKWFEVPGFNIIHAINAWDEDDGNSVVLIAPNIMSIEHTLERMDLVHALVEKVKIDLVTGIVRRHPISARNLDFAVINPAFLGRCSRYVYAAIGDPMPKISGVVKLDVSKGDRDDCTVARRMYGSGCYGGEPFFVARDPGNPEAEEDDGYVVTYVHDEVTGESKFLVMDAKSPELEIVAAVRLPRRVPYGFHGLFVKESDLNKL
What is the function of this protein?
May be involved in carotenoid cleavage.
What are the official names of this protein?
Probable carotenoid cleavage dioxygenase 4, chloroplastic, AtCCD4, AtNCED4.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule.
Protein: SYI_ACIAD
Sequence: MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQDPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQRTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFHIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVG1_HUMAN
Sequence: MASQKQMEVVTKGTGFRRRPKTITYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQFKPQATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKAPAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLATT
What are the official names of this protein?
UPF0193 protein EVG1.
What is the protein family that this protein belongs to?
Belongs to the UPF0193 (EVG1) family.
Protein: GAL1_ECO7I
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIIAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SORPO
Sequence: MTNLRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLIVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SIM11_BOVIN
Sequence: MNWKVLEHFPLLLYILAAKTLILCLAFAGVKVYQRKRLEAKQQKVEAEKRKQAEKKES
What are the official names of this protein?
Small integral membrane protein 11.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FES_DICD3
Sequence: MPAAQPSGFVATLLSSPQAGEEAWWQQVARLGTPLVEAQDSGRVRMTFLWRDPDGDERYSAIRRVYADINGVTDHHSTDPQSLERLPGTDVWHWSMAIEHDWRGSYSLIPIVAAQLPPVFSDDGQLRDEQQREWWCSLFPCAIADPLNRDQSWGEQLSAAHMPAAPSQQAWRAVDNGTALPPDAARLTVLDWKSEQLDNQRRIWLYTTGISDEPAQRPLCIVLDGQKWAEETPLFAALEAETAAGHLPPAVWLFIDAIDGETRCRELPCDAAFWLAVQDELLPQAARLAPFSDDPDRTVVSGQSYGGLAALYAGLHWPQRFGRVLTQSGSFWWPNLQFITDFDQRDTLEPGVLVTEVRQGGQTAWPLVIFQEAGRREADIAFVNQQMHEALVAAGHQVHQRVYAGGHDTLCWRGGLIDGFRWLLTGDDPQAASRD
What is the function of this protein?
Catalyzes the hydrolysis of ferric enterobactin (Fe-Ent).  Is responsible for the release of iron from ferric enterobactin.
What are the official names of this protein?
Iron(III) enterobactin esterase, Enterochelin esterase, Ferric enterobactin esterase.
What is the protein family that this protein belongs to?
Belongs to the Fes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_MYCBP
Sequence: MAAQEQKTLKIDVKTPAGKVDGAIELPAELFDVPANIALMHQVVTAQRAAARQGTHSTKTRGEVSGGGRKPYRQKGTGRARQGSTRAPQFTGGGVVHGPKPRDYSQRTPKKMIAAALRGALSDRARNGRIHAITELVEGQNPSTKSARAFLASLTERKQVLVVIGRSDEAGAKSVRNLPGVHILAPDQLNTYDVLRADDVVFSVEALNAYIAANTTTSEEVSA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS4E_HALS3
Sequence: MTNHQKRLSVPKSWPVERKTETFTAKAGAGPHGESGVPLVVVLRDVLEYVDDTSEAQYAINTDGVLVNGDSVGDVNRPIGMFDILAFPDRDEYYRVFPDEGGRLGLTEIDADAAGSKLNKVTDKTTVSGGRTQLNFHDGSNLALDEDAYAGGDSVVVDTDTNEIVAHFQYEEGALVTAVAGQHAGDIGEIAEINVQPGSASNTVRVDDENGGFETIAEYVVVIDENFVEEDDE
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: TMCAL_BACLD
Sequence: MKAVGLVVEYNPFHNGHLYHIKEAKSETRSEVAVAVMSGSFLQRGEPAIVSKWARTKMALASFADVVVELPYIFAVQKAETFAEGAVSILNELGCSSLFFGSEHGDIEAFLNTAAHTIEHEDRLNEEARKQIAFGLSYPQAMAKAFRSVTREGGNIVDLSKPNNILGFHYVKAIMQKQLSMKPETVKRRSSGYHDSTFPEADRIASATSIRKSIFETGSLADSRFYLPKTTVDELDEYARTFGMWHSPEDYFPFLKYSLHTMDTEELKGIYEVEEGLEHRVKKAIRKAGSFKEYMELLKTKRYTWTRLQRMNTHILTKTKKADVKRMLNETHPAYIRLLGMTKKGQAYLAEKKKSLSAPLITKTGSFSHPSLQLDIKAGQVYSAPLKEPVRTMLTEQEYSLSPIRYDEDSRIFLRK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_XANC8
Sequence: MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSHDDTTPLALPHVVAAIAAATPAAVWVGWSLGGLFALHAAATQPQVRALAMIAATPRFVRGSDWPDAVEREVFVQFGQDLARDYRGTLDRFLALDTLGSAHARSELRSLRETLTARGEPAASALQDGLGLLERTDLRRALATLARPSLWIAGQRDRLVPAAGMHAAAARAPHAQALTIDGGGHAPFLGHADQVAEALHRFVAALP
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.