PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_ERYLH
Sequence: MADTSLMPIPGQVDPVPAPRDITPRADGRVDLMGLPKARIQELFAEAGLDAKQAKLRSKQVYHWLYHRGVTDFEAMTDIAKTMRPWLAERFIVGRPNVVEAQHSTDGTRKWLLQTDDGHDFEMVFIPDADRGTLCVSSQVGCTLNCRFCHTGTMRLVRNLTPGEIVGQVMLARDALGEWPKGRMDGLDDVEDTGHYSADGRLLTNIVMMGMGEPLYNFDNVRDALKLVMDGEGLALSKRRITLSTSGVVPMMERCGEEIGVNLAVSLHAVTKDIRDEIVPINKKYGIEELLQACADYPGASNARRITFEYVMLKDKNDTDEHARELVRLLKQYNLPAKVNLIPFNPWPGAAYECSTPERIRAFSNIVFEGGISAPVRTPRGRDIDAACGQLKTAAQKKSRAERDREAAAEAEAAASQA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CORA7
Sequence: MPTPKKGPRLGGSASQQKHLLSNMAASLIEHGAIKTTDAKAKVLRPYIEKIITKAKAGTVADRRAVLKLIPHKDVVAYLFDELAPKFENREGGYTRIIKLENRSGDNAPMSQISLVLEETVTSEANRATRAAASKQAEEAKAEEAEATEAEAEETTEEK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DBP7_CANGA
Sequence: MSDDESMVLNFSTDTAGIQRADKVTGGRWKDRRKLQQRLGGREPVKRRAEGGDKERGDKRAKVDTGNAQEKKNIPKPVSKADVNINSQIVSSLFTSNRAKQTSENKNKHNSDDKVVPSNAPLTDDSFEGLGVGSLVVSHLENKMRIQKSTSIQKVVIPQILQNADKTDFFIHAQTGSGKTLAYLLPIFSAILGMGDHIDRKSGCFALIIAPTRELASQIYHVTTMLANCCHYLVPCLLIGGERKKSEKARLRKGCNFIIGTPGRILDHFQNTKVIKEQMQSSLRYVVLDEGDKLMELGFEETINQIMEIVNSMDVITRKYPKLPNRIVHLLCSATKNNEVAKLSKRSLDNYKVISIGGKKDTMMDNTSVPDQLLQKVVIAPPKLRLITLAGVLDGIQKKPLDAGSVAKRTIVFLSCADSVDYHFEVFSGNDGLYKNLVGDSVRVLSKGNKILPSIKDEELPGIICYKLHGSLSQQMRTMTLKHFATDSEQTKGKHLILFCTDVASRGLDLPDVSTVIEFDPPFAVEDHLHRIGRTARAGRSGEALLFLLPGEEEGYLDYIQKYHPKGWDLLDAEKDVLIKAFNDIDVARNDKEIKSTGKTFEWDTNATTWHLNVERRILENEQFKEQATKGYISHVRAYATHISAEKQYFNLKGVHLGHLAKSFGLRDRPKAMGMNSSKDANGNERSKPKKENAKNKMFRMARMAAKQSADEFNY
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TRPR_SALAR
Sequence: MTQQSPYSAAMAEQRHQEWLRFVELLKQSYAEDLHIPLLNLMLTPDEREALGTRVRIIEELLRGEMSQRELKNELGAGIATITRGSNSLKSAPVELRQWLDQVLLKEA
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BORBR
Sequence: MAISASAGAAPVITIDGPTASGKGTIAHRVAKQLGWDVLDSGALYRLTALAALRRGLPATDEPAVAAVAQALDVRFDGPHVYLEGRDAGHEIRQEEVGNYASRIAAYPGVRQALLERQRAFRQPPGLVADGRDMGTVVFPDASLKIFLVADVEARAQRRCKQLIEKGISANLDDLLRDMRERDARDTQRAVAPLAPAADAHVLDSSGLTIEQTVQAVLDFWRA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SYNS3
Sequence: MTDSTAIALLSGGLDSATAAALAIKSGFRVIGLSFDYGQRHRRELDAAVEIAKALNLAEHHTINVDLAMWGGSSLTDHAQTLPTSGVETSIIPNTYVPGRNTVFIAIGLSLAEARGADRLVLGVNAVDYSGYPDCRPDYLEAFQDLADLSSRAGREGHGPKLWAPLVEWSKQQIAEEALHLGIPIERTWSCYSGGDVPCGVCDSCRIRDEALLAAGRPDLCSPGRP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NSA1_PICGU
Sequence: MRLIVTCDDSGSAQGGDFVLQEQIPRNRTSPSPISITQVFVEPKASPASRILYSTLYKERYAICCRLDASVSVYDLEDDEKKLVCHREYVELKGCKPVSLHVFSEFDALVMGLDSGKAALVGFHKNTLEKECQIVDLPGGKPIEAFEACPSQPGVFAYGGKENDLRIVKMFEVGKKVKLLESVEVLFAAKNVKNDHLDLRVPIWITKIRFISSKNSYKLITATRYGQLRIYDTNHGRKPAHDYQVCTNPIITLNFAGSNSDEVIITDNRNMVARHSLVSIDKKAFKTNSATVGDIIKPVPRLLGKYQEGGNTGAIFGVSCFKDTFVATGGLDRYLRVYDLETREMVSKVYMGSQIADILFLEGEEEEESEEEVDEEEENNALWDELESNRPAKKQKQT
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein NSA1.
What is the protein family that this protein belongs to?
Belongs to the NSA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NAC_THEAC
Sequence: MIPGRMNSREMRRLMAQMGIKSTEMDDVTKVIFKGKTKDYVIDNAQVTMIEAQGVKTFQVVGTMREVPKEPEEKKEESFPEDDIKLVMEQASVSREKAIEALKASGGEPAQAIMNLMQK
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: SYFB_EHRCJ
Sequence: MKFTFSWLRRYLDTDVSLDVIIKKLSDIGIEVNNVDYCEHLKTFVIAEVLEVNPHHSANKLKICKVSDGKQILQVVCGASNVKVGMKSVLACVGSIMPTDQSIIEVVKLRGVESYGMLCSNDELGIVDHRNSKNGIIELPNTYNVGDTFFPCDPIIEVSITPNRGDCLGVYGIARDLAAAGLGKLKCIGELSNHSNCSSPIEVSVQVDGIVKGRYIKGIKNCESPKWLKDYLLVCGINSISFVVDITNYIMLSFNRPLHVYDANKIKNKLIFKKADNQTEFYALNDKKYILGTENIVAVDLENSIHSVAGVIGSKLSSCLLDTEDIFLESAWFAPVDIVLSSKKIKLSTDSSYRFERFVDPRFLQTGLDLATKMILEYCGGTHFDVVSNEVHVVDNIELNFFPDSVRSIGNVNISNEEIFDFLIKLGFIVDNNNEFLWRVTVPSWRSDIKHSSDIVEEVLRLYGYDKICEEPIPISHVDISDDYHDRLKALLLSEGLMEVITWSFTNMVFAEKLGYSSELLLIDNPISDKLNLMRPSLLLNLLQVVYENQAYGSSEIAIFEIGQVYGFNNICGSNSNVVCGVRYGNNLPRNLYKCDRSVDVFDVKSDVISILQELNIESNSIELRKSDKSYLHPVRSADVYFKDICLGYFGELHPNIVHLYEIKRPVVCFEVFLYKIPKVDVAHKELTESCYQSVKRDFAFLIDKDTSVQHLIDVTKNSNPVLIDNVTVFDLYEGNSIGDNKLSVALSVTFNPVDHTLNDQEIKDASDLIINAVAEKLGGVLRSF
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_CHLRE
Sequence: MAALESFLYTSESVNEGHPDKICDQVSDAVLDACLEQDPDSKVACETCCKTGMVMVFGEITTKAKVDYEAIVRKVCKEIGFTSEDVGLDADKCKVLVHIEEQSPDIGQGVHGMGTKALEEIGAGDQGHMFGYATDETPELMPLTHVLATQLGYKLTEVRKNGVCPWLRPDGKTQVTVEYKREGGAMIPQRVHTILISTQHNPDVTNEKIREDLMEHVIKPVVPAKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSVVASGLAKRCLVQVSYSIAVAEPLSVFVDTYGTGTMPDAEILKLIRKHFDFRPGLIGKNLDLKRGGNKRYQKTAAYGHFGRDDPDFTWETVKKLE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_ACTP7
Sequence: MATNYIFVTGGVVSSLGKGIAAASLASILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRSKMSKANNFTSGKIYSEVLRKERRGDYLGATIQVIPHITNEIKERVIEGGKGRDVVIVEVGGTVGDIESLPFLEALRQLAVDVGREKTLFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRAIPSNERKKIALFCNVPERAVISLKDVDSIYRIPELLKSQGLDTFVCDRFRLDCPEADLSEWEQVLYRQANPTGEVTIGMVGKYVELPDAYKSVNEALKHAGLTNRLTVNIKYIDSQDIETKGVELLHGLDAILVPGGFGYRGVEGKIRTAQYARENKIPYLGICLGMQIALIEYARNVAGLTQANSSEFDKDCPQPVVGLITEWQDESGNVETRSDESDLGGTMRLGAQQCHLIEGTKAREVYGAETIVERHRHRYEVNNTLLPQIEAAGLKVSGLSADRKLVEIIEIPNHPWFIAAQFHPEFTSTPRDGHPLFAGFVKAAKDYQDSHKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: APEX1_DANRE
Sequence: MPKRAKKNEEGVDGEADNGTAAAKKEKKGKEPEAPILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITGMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV
What is the function of this protein?
Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.  Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.  May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.  Required for passage through the midblastula transition MBT.  May also act as an endoribonuclease involved in the control of single-stranded RNA metabolism.  Has no redox activity.  Binds DNA and RNA.
What are the official names of this protein?
DNA-(apurinic or apyrimidinic site) endonuclease, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, zAP1.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus speckle. Endoplasmic reticulum. Cytoplasm. Mitochondrion.
Protein: DFB39_RAT
Sequence: MKISCFLLLVLSLSCFQINSVSGIDSVKCFQKNNTCHTIRCPYFQDEVGTCYEGRGKCCQKRLLSIRVPKKKV
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 39, BD-39, Defensin, beta 39.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_SHESA
Sequence: MVKKNSKKAAPATIARNKRATFEYRFEEKMEAGISLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPIRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PFKA_SALA4
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_NITOC
Sequence: MRIALGLEYDGSNFSGWQSQKGVRTVQATLEQALSAVANEPVTVITAGRTDAGVHAAAQVVHFDTATFRLEHNWVFGGNANLLPEVAILWAQPVNEAFHARFSAIARHYRYIILNRGARPAIANRRVTWYCQPLSVTKMKEAGAFLVGEHDFSSFRAKACQAKSPVRNVHYLEVTRQGDWIVIDISANAFLHHMVRNIAGVLMAIGKGEQPPRWAEEVLQARCRAVGGVTARPDGLYLVRVDYPDHFDLPRLSRPVTVW
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TIPL_LAMBD
Sequence: MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNEKGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVGGTVVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDGAVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ
What is the function of this protein?
Part of the distal tail tip complex which plays a role in DNA ejection during entry, and in tail assembly initiation during exit.  The tail tip complex is assembled successively with three tail tip proteins J, one tail tip protein I, one tail tip protein L and one tail tip protein K.  The tail tip complex interacts with tail measure protein to initiate tail tube assembly.  The formation of the tail tip complex is completed by the addition of tail tip protein M, which is followed by tail tube polymerization.
What are the official names of this protein?
Tail tip protein L.
What is the protein family that this protein belongs to?
Belongs to the lambda-like tail tip protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GSA_CLOTE
Sequence: MNNLEIFKESEKYMPGGVNSPVRAFSNASINPPIIKKGLGSRIVDEEGKEYIDFVASWGPMILGHNDPEVVEAIQNTVEDAISFGAPTELELKLAKHMVETLDNIDMVRMVNSGTEATMSAIKLARGYTRRDRIIKFAGCYHGHFDGFLVEAGSGVLTERIPGSPGVPKGSIENTLIAEYNHIDTVEALFEKYPEEIAAIIIEPIAGNMGTIPAKTEFLQRLREICTKYGALLIFDEVMTGFRVAYKGAQSRYGVKPDLTTYAKIMGGGLPSGAYGGRRDIMEKLSPIGPVYQAGTMSGNPVVMAAGYTTLRKLYNNPSYYEHMEKIGAELQKGIEIVAKEKGLPVVVNRCGAMLTPFFSKRDKVADYEDAKSSDTELYGRFFEHMIKSGIYIAPSQFEAMFIGVKHDIYEVERFLEAMRKF
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_VIBCH
Sequence: MDKIKVGLQYWIPQHALTRLVGKLASARAGSLTTAIIRWFIKQYNVNMDEALHSDPTHFKTFNEFFVRELKAGVRPIAEGEKVITHPADACVSQFGAIEYGKLIQAKGHTYSAQELLGGDAKLAEEFRDGDFATLYLSPRDYHRVHMPCDGTLRQMIYVPGDLFSVNPLTAENVPNLFARNERVVCIFDTEFGPMAQVLVGATIVGSIELVWAGTVTPPRGNTVYRWDYPANGNQAVVLKKGEEMGRFKLGSTVINLFAKQAIRFDDSMALGAPTRMGEPYAHQA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNPH_CAUVN
Sequence: MRPSERAPDQLRAVTLETGVNRYAEGSCLIGFGHTKVLVTATVEENVPGWMRNKGAGWVTAEYGMLPRATHTRGRREAAAGKQTGRTQEIQRLIGRSLRAVVDLKALGERQITLDCDVVQADGGTRTAAITGAWVALRLATKYLLDEGVLKTDPILGQVAAVSCGVFNGVPVLDLDYEEDSNAEADSNFVLTGVGDIVEIQATGEKRGFTRAEFESLYGLAEKGINELFALQRAAIGG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TOIP1_BOVIN
Sequence: MAGEGQRAEPEREGWALYVTPRAPLREGRPRLAPQNGGSGDVPAYGTPTPSRHGRREVRFSEEPPEVYGDFEPRAAKEKARVGRQIPLEGFRPDSAKEEVRESAYYLRSRQRRQPRLHEAEEMQTRRAALLQQQPHSPPPPLRPSPVTTRRGLRDSHSSEEDEPPSQTVLSQTVTKKAIRRTQETPVMSEDPLISLRRPPLRSSRSEAASVQQKVNFLEEGETEENDQDSFDSDVTVKVRSGDSVESGDQTTRSSSQYKESFWQSSQSGDFTAFDEQPLKLSSGYQKTPQEWAEKTVRIRTRMLTSSPGMRSIYGSFSDDDSVQKSELGNQSPSTSNQQMTGQPKSVSSVKTKRYWPFAVIAALLIGGFLYTRPPEAETTAVQEFQNQMKQLMNKYQGQDEKLWKRSQTFLEKHLNGSQSRPQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVPAIRIDGASKATRDSDTVKEEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHESAAFKDVALVLTVLLEEETLGTSLGLKEIEEKVRDFLQVKFTNSDTPNSYKHMDPDKLSGLWSRISHLVLPVQPENDLKKGICL
What is the function of this protein?
Required for nuclear membrane integrity.  Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane.  Binds to A- and B-type lamins.  Possible role in membrane attachment and assembly of the nuclear lamina (By similarity).
What are the official names of this protein?
Torsin-1A-interacting protein 1, Lamin-associated protein 1B, LAP1B.
What is the protein family that this protein belongs to?
Belongs to the TOR1AIP family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein.
Protein: UPP_BURM1
Sequence: MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HSDL1_RAT
Sequence: MAAVDSFYLLYREIARSCSCYVEALALVGAWYTARKSIPVICDFYSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNIILISQEEEKLQAVAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQYFSQVPEDTIWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSVTAPGSFLRRCPWLAPSPRVYAQHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNRSLRKEALSSQA
What are the official names of this protein?
Inactive hydroxysteroid dehydrogenase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: H1_PEA
Sequence: MATEEPIVAVETVPEPIVTEPTTITEPEVPEKEEPKAEVEKTKKAKGSKPKKASKPRNPASHPTYEEMIKDAIVSLKEKNGSSQYAIAKFIEEKQKQLPANFKKLLLQNLKKNVASGKLIKVKGSFKLSAAAKKPAVAKPKAKTAAKAKSVKAKPAAKPKAKAVVKPKVASKAKAVAAKPKKAAAKPKTVAAKTKPTAAKPKAVVKPKSKVKPAKVAKTSVKTTPGKKVAAVKKVAAKKVPVKSVKAKSVKSPVKKVSVKRGGRK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1, PsH1b, PsH1b-40.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS12_ARTPT
Sequence: MPTIQQLIRSAREKTDKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKDRRNGRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL34_STRZJ
Sequence: MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: EFP1_CHLTR
Sequence: MVLSSQLSVGMFISTKDGLYKVVSVSKVSGNKGDTFIKVSLQAAGSDVTVERNFKAGQEVKEAQFEPRNLEYLYLEEDKYLFLDLGNYDKIYIPKEIMKDNAMFLKAGVTVFALVHEGTVFSMELPHFLELMVAKTDFPGDSLSLSGGAKKALLETGVEVLVPPFVEIGDVIKVDTRTCEYIQRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P 1, EF-P 1.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATD_COPPD
Sequence: MASTVSPNRMTLLALKRRYTISKRGLKLLKDKLEAMVKAFRDLYTEFDRERRYIEELMEAFVELLNQYESETSPAVRDRIRSMQLFQVEYELSTRMVFNIKVPFLDVSLKRMDIPDLYLQTGPAFYKALSVYEELLPHLLKLASLRNALHMMSVEIEKTRRRSNALEYNVVPELERTIKWVQQYLDEMERSQTVRIMKVKSMLEKERGNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: HHP4_ARATH
Sequence: MGDEAEIKEHLKPQASSETMDKKHNVKGKRLWQKVKYQLVEFHSLPAYLRDNEYIIGHYRSEWPIKQILLSIFTIHNETLNVWTHLIGFFLFLALTIYTATKVPSVVDLHSLQHRLPDLLRKTDLHKLHSELMARLPSSPSSWHVMDLLYNCLPERFSHGNYTDMCVLHSVREDLANLIAPLIFRPITRWPFYAFLGGAMFCLLASSTCHLLSCHSERVSYIMLRLDYAGIAALIATSFYPPVYYSFMCDPFFCNLYLGFITILGIATVLVSLLPVFQSPEFRVVRASLFFGMGFSGLAPILHKLIIFWDQPEALHTTGYEILMGLLYGLGALVYATRIPERWMPGKFDIAGHSHQLFHVLVVAGAFTHYRAGLVYLKWRDIEGC
What is the function of this protein?
May play a role in abiotic stress response.
What are the official names of this protein?
Heptahelical transmembrane protein 4, PAQR family protein HHP4.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.