PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_MYCGE
Sequence: MITSIFGKVTFVGKRKIIVEHNWISYWFNTKENHKFEKNLEKNKQIFCHIIKKIVANQIIEEAFAFNTLEEKEWFCRLIELNGIGSKTALNLLNNDLEEIKQYILENNYSALCGINGVNNKIARALLSLEIFEKSENNKNIKGVQVADGYDELFETLKSLGYKQQEIQDALKMIEVKPDFDISQLVAEVIKLMSFKNNEITNKTA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NU4LM_YARLI
Sequence: MFIGTIILVLSFLGFVFNRRNIILAFICLETMLLGINLILLRNSVLFDDISGSLFAIVIIILAGVESAIGLSLLVSYYRLRGVINSYGI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HSP1_PIG
Sequence: MARYRCCRSHSRSRCRPRRRRCRRRRRRCCPRRRRAVCCRRYTVIRCRRC
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NLT41_HORVU
Sequence: MARAAASQLVLVALVAAMLLVAADAAISCGQVSSALSPCISYARGNGAKPPAACCSGVKRLAGAAQSTADKQAACKCIKSAAGGLNAGKAAGIPSMCGVSVPYAISASVDCSKIR
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 4.1, LTP 4.1, CW-21, CW21.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: CLPX_KINRD
Sequence: MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAEANDLGLVELPKPKEIFDFLDQYVIGQSSAKKSLAVAVYNHYKRIQVGEPSTKGREDAVEISKSNILLIGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFAGLDRIIEARSGKQGLGFGAQLRSTTEKKAEPSFADVMPEDLMKFGLIPEFIGRLPIITSVENLDQEALVQILTKPRNALAKQYQRMFELDGVELEFTDDALEAVADQAILRGTGARGLRAIIEEVLLPVMFDVPSRDDIARVVVTREVVLKNVNPTLVPREAPARKPTRERREKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YOX1_YEAST
Sequence: MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTPLNSKKRDYSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQKKTLTPVKTSPNSRVNKLINSIDHSPSKAKRPVSNPSGSPKRKRKFGFKIVDQQPLKDLDPNAFRG
What is the function of this protein?
Transcriptional repressor required to restrict transcription of ECB-dependent genes to the G1/M phase by repressing their transcription during the interval from late G1 to M phases.  Genes that contain a ECB (early cell box) element in their transcription regulatory region are transcribed only during G1/M phases.  In vitro, is capable of binding to the DNA of the leucine tRNA gene.
What are the official names of this protein?
Homeobox protein YOX1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRS2_METTM
Sequence: MVKFNNIVYDPQLTDKKFPVKASDPEREAKLVVLQPVGYPFVCNLMESPRIDAVNKELFEIYARDQWEGFSATEGSYLFDQKLLPDYAFKIIRAHPDGSKITRNTSIILLENEREEFHEVKSDITMDDVIGQEDAKIKCRIIMRYLEDPDRFRDWAPRNVLFHGSPGTGKTMLAKSLANELRVPLYLIKATSLIGEHVGDGARQIHELYELASKTAPSVIFIDEMDAIGLDRRFQSLRGDVSEVVNALLTEMDGINQNWGVVTIGATNNPELLDNAIRSRFEEEIEFKLPGDDERRMMLEKYIETMPLDVDFSVDKLVKLTKGMSGRDIKERVLKTALHRALADESPRVEREHIEYALKERDLKSEPRHMFA
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
Putative 26S proteasome regulatory subunit homolog MTBMA_c13930.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: ADF3_ARATH
Sequence: MANAASGMAVHDDCKLKFMELKTKRTHRFIIYKIEELQKQVIVEKIGEPGQTHEDLAASLPADECRYAIFDFDFVSSEGVPRSRIFFVAWSPDTARVRSKMIYASSKDRFKRELDGIQVELQATDPTEMDLDVFKSRAN
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers.
What are the official names of this protein?
Actin-depolymerizing factor 3, ADF-3, AtADF3.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TNI3K_PONAB
Sequence: MGNYKSRPTQTCTDEWKKKVSESYVITIERLEDDLKIKEKELTELRNIFGSDEAFSKVNLNYHTENGLSLLHLCCICGGNKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHGGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQNDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIHLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIVTLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVARGMEYLHNLTQPIIHRDLNRSLKYLSAFCCCPNHLFLTAHTIYLLAP
What is the function of this protein?
May play a role in cardiac physiology.
What are the official names of this protein?
Serine/threonine-protein kinase TNNI3K, TNNI3-interacting kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Expressed at lower levels in the cytoplasm.
Protein: RAS_ARTSA
Sequence: GGVGKSALTIQLIQNHFVDEYDPTIEDSYRQQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNNAKSFEDISAYREQIKRVKDAEEVPMVLVGNKCDLPTRAVDMSQAREVARQYGIPFVETSAKTRMGVDDGFYTLVREIKKDKMKKGNSSRRGRSGRKQLKCSIL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: KXDL1_HUMAN
Sequence: MDLPDSASRVFCGRILSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMSERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASFLEEEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHVQPGSPAINGRSQTDDEEMTGE
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).  May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).
What are the official names of this protein?
KxDL motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: GPDA_TREDE
Sequence: MNDKIAIIGAGSWGTAVACSLGKNGHRVVLWSHTAGVADSINTEHINVKYLPKHKLPKTVSASTDMEEVCKDASFIFLASPSLYLTSAVEELLKFAPFSHDDGEMPYPTIAVLTKGFIPDENGEPQFIIDVLEKMLPDFYKNHLVYVAGPSHGEEVAEGKLTGLIAASQNPMCSIRCREILRSRSLLVYSSLDIIGVQVCAAAKNVVAVAFGVLDALTVTSDIFGDNTESLLLAAGLNEIQTIGRAMGATHPETFTSISGVGDLDVTCRSKYGRNRRFGNEIITKKILLSFENLDDLIKNIDKIGYLPEGVVACKYLNILAEKRNLKLPICSGLYKILNKELKPLDLIENLLQGDTK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_LEPCP
Sequence: MNTFSAKPAEVVHEWFVIDATDKVLGRVASEVALRLRGKHKAIYTPHVDTGDFIVVVNAEKLRVTGTKSIDKKYYRHSGYPGGIFETNFRDMQAKHPGRALQKAVKGMLPKGPLGYAMIKKLKVYAGDTHPHAAQQPKTLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL9_CORJK
Sequence: MKLILTANVDNLGVPGDIVEVKAGYGRNYLLPRGYAIVATRGAEKQIEGIKRAQEARQIRDLDHAREVKEELENLSGVTISVRTAESGKMFGSVTADNIVDAVKKANGRSLDKHSIKLRKGDVKATGVYSVDVQLHEGIVASLSFEVVSA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NTPP2_JANSC
Sequence: MKLILGSGSPRRVEILAVLGLTPDDIRPPDIDEDPLPSELPRPYVDRIIRAKAEAVPSDPGDVVLCADTTVAVGRRILGKPADEAEARAFLTLLGGRRHRVLTGLAVKTDDRLMTRIVESRVKMKRLSKVEMDGYMATGDWQGKAGGYAIHGPAGAFFPWISGSHSAIVGLPMVETAHLLQAAGIEVWKT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase 2, Nucleotide pyrophosphatase 2, Nucleotide PPase 2.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX23_GIBZE
Sequence: MSSSTPKDTVDTAETPKVKDPESQAWSDDKRRKFETKSKSEFYDPCQEAAQASYRCLFRNGGDKNMCGEYFQAYRDCKQEWTEKRRREGRGWF
What is the function of this protein?
Required for the assembly of cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase-assembly factor COX23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX23 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: PYR1_ANASL
Sequence: MAITAAASRLGTEPF
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with phycocyanin.
Protein: VIME_CYPCA
Sequence: MASRTNTSSYKRMFGGERPAMVRSTYSSRQYSSPVRTTSRVSYSSASSASPSIYMSKGARVRSSGPLPRLATETLDFGLADAINTEFKTNRTNEKAEMQHLNDRFASYIDKVRFLEQQNKILIAELEQMRGKGSSRVGDLYQDEMRELRRQVDQLTNEKATVEVDRDNLGEDIERLKEKLQEEMLQREDAENTLRGFRQDVDNASLARLHLETKVESLQEEIAFLKKLHDEELAELQIQIQEQHVQIDMEVAKPDLTAALKDVRQQYETLASRNLQESEEWYKSKFADLSEAAARNNEAIRLAKQEANDYRRQLQSLTCDLEALKGTNESLERQLREMEDNFSMEASGYQDTIARLEDDIRNMKDEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRITTPFPNLSSLTLRETMKETRPAMDSLSKKVVIKTIETRDGHIINESSQNDDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix.
Protein: RR12_CHLVU
Sequence: MPTIQQLVRSARTRLSKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDSAGVKDRSQSRSKYGVKRPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENO_CHLPD
Sequence: MPIIRKILARQILDSRGNPTVEVDVYTENSFGRAAVPSGASTGVHEAVELRDGDSAVYLGKGVLKAVDHVNTVINDRLKGMFVTDQEEIDMAMLALDGTPNKSRLGANALLGVSMACAKAGAEYSGLPLYRYIGGTMANTLPVPMMNVLNGGAHADNTVDFQEFMIMPVGFSSYSDALRSGAEIFHALKSLLKSKGLSTAVGDEGGFAPNLKSNEEAIELVIEAVGKAGYKIGSSTANGGLGDAQVMIALDPASSEFYDAAKQKYVFKKSSKQELSSLEMAEYWEKWASDYPIISIEDGMAEDDWDGWKILTDKIGSRVQLVGDDLFVTNTSRLALGIERGVGNSILVKVNQIGTLTETLQAIDLARRNGYTAVISHRSGETEDSTIAQIAVATNAGQIKTGSLSRSDRMAKYNELLRIEEELGLQAKYPALSAFRV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MDTI_SALHS
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HS3S5_HUMAN
Sequence: MLFKQQAWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPIEGRLGGARTQAEFPLRALQFKRGLLHEFRKGNASKEQVRLHDLVQQLPKAIIIGVRKGGTRALLEMLNLHPAVVKASQEIHFFDNDENYGKGIEWYRKKMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRLITEPLPELQLVEKFLNLPPRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVITKLRKFFHPFNQKFYQITGRTLNWP
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan.  Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact).  This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.  Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2.  The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry.
What are the official names of this protein?
Heparan sulfate glucosamine 3-O-sulfotransferase 5, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5, 3-OST-5, Heparan sulfate 3-O-sulfotransferase 5, h3-OST-5.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
Protein: EFTU_CHLPB
Sequence: MAKEAYKRDKPHVNIGTIGHVDHGKTTLTAAITSVLAKAGNAEMREFGDIDKAPEERERGITISTAHVEYQTEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVFLNKVDIADPELLELVELELRELLTEYDFPGDDIPIIKGSALKALEGDAEAEKAIMELMDAVDDYIPEPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGVVKINEEVELVGIKPTKKTVVTGIEMFQKILDQGQAGDNAGLLFRGVGKDEIERGMVVAKPGTITPHTKFKAEVYILKKEEGGRHTPFFNNYRPQFYFRTTDVTGAVTLPEGVEMVMPGDNLSIEVELIVPIAMDENLRFAIREGGRTVGAGTVTQIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPP6_DANRE
Sequence: MTRTLLKIYTLFILLLCRQRDANRKLLVFLIDGFRHDYMDDLHNLPGFREIVENGVKVDYLTPDFPSLSYPNYYSLMTGRHCEVHQMTGNYMWDTDTQKEFLIGTNPDSRLPMWWDGSEPLWVTMQKLGKKVYMYYWPGCEVTILGVRPTFCEEYVYNPSEKNLTDSMENALNALKSSKADMAGIYYEKIDVEGHHFGPRSPEIQRAIRSLDQAFQILNQKIREKNMRDTINVVLFSDHGMTQLKWMEKIIELDNYINMSHIIKMMDRGPVVSLWPKQDKFEEIYQNLSTADNMNVYKKHEIPDRFHYKNGQFVSTLTLVAEPGWFITENKAKLPFWNNGTEAAGGWQHGWHGYDNEFVDMRGSFLAQGPDFKSNYRAGPIRTVDVYNVLCKTLGMNPLPNNGSWSRVECMMRSSAATAGASLISCCFLLLLTLTGVC
What is the function of this protein?
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells.  Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids.  In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids.
What are the official names of this protein?
Glycerophosphocholine cholinephosphodiesterase ENPP6, GPC-Cpde, Choline-specific glycerophosphodiester phosphodiesterase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 6, E-NPP 6, NPP-6.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MAD1_XENTR
Sequence: MAAPVCVNIQMLLEAAEYLERREREAEHGYASMLPYNSKERDGLKRKSKSKKSSNSRSTHNEMEKNRRAHLRLCLEKLKILVPLGPESNRHTTLSLLTRAKSHIKKLEDCDKRSLHQIEQLQREQRHLKRQLEKFGVERTRMDSIGSAMSSERSDSDREEIDVDVESTDYLTADLDWSSSSSSVSDLDERGSMQSICSDEGYSSSGLKRIELQDNPKITAL
What is the function of this protein?
Transcriptional repressor.  MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.  MAD thus antagonizes MYC transcriptional activity by competing for MAX (By similarity).
What are the official names of this protein?
Max dimerization protein 1, Max dimerizer 1, Protein MAD.
What are the subcellular locations of this protein?
Nucleus.
Protein: MFSC_ASPFU
Sequence: MTSNKKSRLPPYQPGEHVSPSVHLNCVLLTTTVVNFLDLFQLSSVLFALPNIQQALGFASEDINWVLIVYNITFAAFLLIAGQLGQRFGLEKIFIAGTATLTISNVINTTAPNKGALLAGRAISGVGAGLTAPNGLAILSNTFPDPESRNKALAIYTACGPLGSTIGTVVGSHLACMSGWRSIFWLCLILTGLSTILACLFLPRFAKRKDMPIDIPGTVVFTAGVALLVYGLNDSSRRGWTSAAMLTGIILGVCLLFVFLWVEAKVSNPAISSYLWKSGPFLVMLVAIFAFGGSFSTWFFISTQLCVNLLGYSTILTAVYFLPAAFAAIASGVFATPLIRLAGEKNILVAGLAITAAGAVAWAFAGPRIGPAVPTTGRDTAIIFVIGSPVALVPTQSILLREVEAGNHAVAGALFNTAYQVGASVILAGANALMDRSRANVQGVRQVTIDGYLNAFWLIAGVLGAAALTVMVCYWPGKDDLVERQTEEANAVGPLAVDKVDTSKDATASARSVADTRL
What is the function of this protein?
Major facilitator superfamily transporter that may be involved in A. fumigatus adaptation to azoles such as vorizonazole.
What are the official names of this protein?
Major facilitator superfamily multidrug transporter mfsC.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ALG3_PICGU
Sequence: MEETHEPKKHSEKEEIEDGLSSKTEAPHLPEFTFKNVCNDIINGVIALFMDPFCNAIVVPILVVFTSIACKIVIANVKYTEIDFKTYMQQIDMINDGELDYSLIAGDTGPIVYPAGFVQIYQWLSWLSSGGEDIPVVQSVFGYLHTLTVLLTCCTYSLVGDVQPWAYMLIVASKRLMSIYVLRLFNDCFTTACMVGVTLVLQAASYWFDTLGSTLVFLLTLVAADLYSMAISIKMNALLFMPAFLIVVYFLCMENILKLLAVILVMVLVQVMVGWKFLLVLFHDEDANYLRMTYLQRAFDFKRSFLYEWTVNWRFVPEEYFTSKLFANFLLVCHISVLIFFVISRFFSSKITGKSLVTLVKDGFKPFNTIASTNLYVNKKQGPKLILLTFATTNTIGVLLSRSLHYQFLSWYCWHMPFLLYSTGWGPIISGAMWAVHEWCWLTFPSTIQSSAILVTILSFTLATVWHRGENWYGS
What is the function of this protein?
Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Asparagine-linked glycosylation protein 6, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UPP_ACTPJ
Sequence: MKIVEVKHPLVKHKLGLMRAADINTKDFRALATEVGSLLTYEATTDLETEAIEIDGWCGKVEVERIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRNEETLEPVPYFTKLANDVEERLAIIVDPMLATGGSMIATIDLLKKAGCKQIKVLVLVAAPEGIKALEAAHPDVELYTASIDSHLNEHGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: FIMI_SALTI
Sequence: MIRKGAALVGLVLMSPVIAQPVMVESGRVHLRGQLVNGGCAVATESQDLRVLMGQYRTNAFTGPGSFAPVSVPFSLRLISCSAEVWRHVGIAFAGVTPAEDPHVFLASGEGIGNAGIGLALFDDQQRQIIPNTLPLHYAPILTSEMTLHFTARYRAISENMTPGRIHSEVWFTLVYP
What are the official names of this protein?
Putative fimbrin-like protein FimI.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: Y3454_ACIBY
Sequence: MTKQYMTHRCLIAPPEMADDFFANTVIYLARHDEEGAQGIIINRPAGIQIKELLNDLDIDADNVNPHEVLQGGPLRPEAGFVLHTGQPTWHSSIAVGENVCITTSKDILDAIAHNEGVGRYQIALGYASWGKNQLEDEIARGDWLICDADMDLIFNLPYDDRWDAAYKKIGVDRTWLASEIGHA
What are the official names of this protein?
UPF0301 protein ABAYE3454.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.