PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_MICAN
Sequence: MVATTETNVGKIVQIIGPVIDAEFPSGKLPRIYNALTVKGTNSAGQNLSVTCEVQQLLGDNQVRAVAMSTTDGLVRGMDIVDTGAAISVPVGKCTLGRIFNVLGEPVDEKGPVNVTETSPIHRPAPKLVDLEVTPTVFETGIKVIDLLTPYRQGGKIGLFGGAGVGKTVIMMELINNIAIQHGGVSVFGGVGERTREGNDLYNEMIESKVINADNPEDSKIALVYGQMNEPPGARMRVGLSALTMAEYFRDVSKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGDLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDGTTVLSRGLASKGIYPAVDPLGSTSTMLQADIVGDEHYGTARAVQSTLQRYKELQDIIAILGLDELSEEDRLTVDRARKIERFLSQPFFVAEVFTGSPGKYVTLADTIKGFQMILKGELDSLPEQAFYMVGSIDEAIAKGEKLKKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RR14_HELSJ
Sequence: MAKKSLIVREYKKNILVNKYYKKRLLLKSQLNNTINSTDCILKILNKLQKLPKKSSPTKLRNRCTLTGRARGVYSEYKISRFVFRNLALNGLLPGVFKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
Plastid 30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid.
Protein: GLB3_CHITH
Sequence: MKFLILALCFAAASALSADQISTVQASFDKVKGDPVGILYAVFKADPSIMAKFTQFAGKDLESIKGTAPFEIHANRIVGFFSKIIGELPNIEADVNTFVASHKPRGVTHDQLNNFRAGFVSYMKAHTDFAGAEAAWGATLDTFFGMIFSKM
What are the official names of this protein?
Globin CTT-III, Erythrocruorin III.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL19_SHEAM
Sequence: MNNIIKMLNDEQMKKDVPDFGPGDTVVVQVRVKEGDKERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPLISSIEVKRRGRVRRAKLYYLRERSGKSARIREKLATK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: METK_CHLL3
Sequence: MSQSRYFFTSESVSEGHPDKVADQISDAVLDDFIRQDPNSRVACETFVTTGQVIVGGEVTTTGIVDVQKIARKVITEIGYTKGEYMFEANSCGVLSALHSQSADINRGVDRKEAIADEFDRVGAGDQGMMFGYACTETPELMPAAIQFAQQLVKVLADIRKAGKIMTYLRPDAKSQVTLEYVDEKVARVDAVVVSTQHDPEPAGMSEAEFQEVIKKDIIENVIKKVIPANLLDLNTKFHINPTGRFEIGGPHGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYASRHVAKNIVAAGLAEKCTVQVSYAIGVARPVSIYINTHGTAMHGLSDEQIQEKAEKIFDLRPLAIIRRFSLDNPQGWCYQETAAYGHFGRDIFPWEKTEKVAELKTAFSLA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_RIPO1
Sequence: MSIEFSKYQGLGNDFILIDNRSSHTPLVSPEQAIKMCDRHFGIGADGVIFVLPGTANTDYTMRIFNSDGSEPQMCGNGIRCLARFIAHLEGGETLGKTYQIDTLAGVISPRLEAQGQVKVDMGTPYLLAKEIPTTLGNSNDKVINHSLEVAGQTWLVTCVSMGNPHCITFVKDVWGIDLPTLGPQFEHHPGFPERTNTEFIEVVRRDYVKMRVWERGAGITLACGTGACASVVAGVLTNQCDRYCIVELPGGNLTIEWSEMDNRIYMTGPAELVFTGIYNL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_PSET1
Sequence: MALTHLQQLEAESIKIMREVAAEFENPVMLYSIGKDSSVLLHLARKAFYPAKIPFPLLHVDTNWKFSEMIEFRDRIAKEYGFELLVHKNPEGMEIGISPFEHGSGKHTDIMKTQGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKHHRWDPKNQRPELWNTYNSQVNPGESIRVFPLSNWTELDIWQYIYQENIDMVPLYLAKERPVVDRDGTLIMVDDERMPLLEGEVPMMKSVRFRTLGCYPLTGAVESTASSLTEIIEEMLLSTSSEREGRVIDHDSAGSMEKKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: FTSB_RALPJ
Sequence: MRLITLFLLLLLLAIQYPLWLGKGGWLRVWDMQKQVTAQNQRNAELKQRNTKLEGEVKDLKEGTGAIEERARYELGMVKDDEGFVQFVAPAPKTSETPLPPPPPAGQQAHH
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: TTLL4_CAEEL
Sequence: MSSGYSSAPSVSHTSSDTDLNRIDSYDDGAEETTDEQRMCGLSELVTSCLTSSRLKAIDEEDEEENCNDIEIVGLSKTTTKVKRSKKVLSCPIVSSSTKKENGNAAPFLKSSQFTDVPPTIRFYTKGTKVTKPARKIQARLTWCHNSLLPIVMRQTLAASHFTVVDESLFYVGYWGRHLKSAQYRALQPHQKVNHFPGAFHIGRKDRLWMHIRKQQERFEGEFDIMPFTYILPTDRQELLKYLETDASRHVIVKPPASARGTGISVTRKPKDFPTTATLVAQHYIERPLTINRAKFDLRLYAYVPTFEPLRVYIYDQGLVRFASVPYSHSVSTISNKYMHLTNYSINKLAEADGVANKPVPKWTLHHLWEHFDEMGVDREKIQREIEEVIIKAFISTEKPIREHMSRFLEQEFICYELFGIDIILDEDYKPWLLEVNISPSLHSGTPLDVSVKAPLAKDVLNLAGVYVPPSFDKLSDADYSTRPRNGRKNREQLIKEASWVAAYKDQLGVIDNRIFKRLTPEDTRALVEFEDELERIGDFKLVFPTAHTSHYQKYFAETIYMNILLQQWQIAQEDDRSIGINRLEQLCRQKHMQSDQETSF
What is the function of this protein?
Monoglutamylase which modifies tubulin, adding a single glutamate on the gamma-carboxyl group of specific glutamate residues of target proteins (PubMed:32747782).  Involved in the side-chain initiation step of the polyglutamylation reaction but not in the elongation step.  Preferentially modifies beta-tail tubulin over the alpha-tubulin (PubMed:32747782).  Involved in side-chain glutamylation of tubulin in sensory cilia (PubMed:20519502, PubMed:27635036, PubMed:29849065).  Together with ttll-5 and ttll-11, required for male mating (PubMed:27635036).
What are the official names of this protein?
Tubulin polyglutamylase ttll-4, Tubulin--tyrosine ligase-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: GPN3_YARLI
Sequence: MSRVGILVLGPAGVGKSTFCNALITHIQSIGRRAHIVNLDPAAEPNEYEFTVDIRDLISLNDVMEEMELGPNGGLMYCFEFLLQNMDWLEEELGEFEDEYLIFDCPGQIELYTHVPVLPTIVKHLQRHMGFSLCACYILEAPFVLDRPKFFSGVLSAMSAMILLETPHINILSKMDLIKDEVPKRELKRFLNPDPLLMVDEANSQTNPKFHQLNLAITNMIEDFGMVQFLPLEAKNPDSVAAILSYLDDVTQWADNQEPKEPKVEEVEEEE
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: Y869_TREPA
Sequence: MRSCPKRARGVHWATGAALWCPSRMIFEKISPLQAFVWAVLRLFLKSFRTVFRGAVRAGCGVLACVRAYGFPPYGSKE
What are the official names of this protein?
Uncharacterized protein TP_0869.
Protein: ATPB_FRATN
Sequence: MSTGKIIQVIGAVIDVEFARDNTPKVYDALNVVEAGLVLEVQQQIGDGVVRTIAMGSSDGLRRGMEVKNTNAPISVPVGHGTLGRIMNVLGEPIDEAGPIEYTEKRSIHQAPPAYDELALSTEILETGIKVVDLICPFAKGGKVGLFGGAGVGKTVTMMELINNIAKEHSGYSVFAGVGERTREGNDFYYEMKDSNVLDKVSLVYGQMNEPPGNRLRVALSGLTIAEGFRDEKRDVLMFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAAEMGALQERITSTKTGSITSVQAVYVPADDLTDPSPATTFSHLDATIVLSRQIAELGIYPAVDPLDSTSRQLDPLVVGQEHYETARAVQKVLQRYKELKDIIAILGMDELSDEDKKIVDRARKIQRFLSQPFHVAEVFTGNPGKFVSLKDTVASFKAIVNGEYDHLPEQAFYMVGSIQEAIEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALDH_PARDP
Sequence: MPNDQTHPFRGVNALPFEERYDNFIGGEWVAPVSGRYFTNTTPITGAEIGQIARSEAGDIELALDAAHAAKEKWGATSPAERANIMLKIADRMERNLELLATAETWDNGKPIRETMAADLPLAIDHFRYFAGVLRAQEGSISQIDDDTVAYHFHEPLGVVGQIIPWNFPLLMACWKLAPAIAAGNCVVLKPAEQTPAGIMVWANLIGDLLPPGVLNIVNGFGLEAGKPLASSNRIAKIAFTGETTTGRLIMQYASENLIPVTLELGGKSPNIFFADVAREDDDFFDKALEGFTMFALNQGEVCTCPSRVLIQESIYDKFMERAVQRVQAIKQGDPRESDTMIGAQASSEQKEKILSYLDIGKKEGAEVLTGGKAADLGGELSGGYYIEPTIFRGNNKMRIFQEEIFGPVVSVTTFKDQAEALEIANDTLYGLGAGVWSRDANTCYRMGRGIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQTKNMLVSYSPKKLGFF
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of acetaldehyde to acetate.
What are the official names of this protein?
Aldehyde dehydrogenase, Acetaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: 36022_ASFM2
Sequence: MMPSTLQTLAKKTLATQHISKKYWPSEEYCYILKCCGLWWHDSPITIFTCIKQILIKTANFKHGLDLNLALMKAVQENNYELIMLFTEWGADINLGLITVNTECTRDLCQKLGAKEALSAKEILEIFYKIQYIKSSNNIIISHELISNHPLFLNNDQLKLRIVGELNAISINFILDEISFNEMLTRYWYSMAILYKLPAAIQYFYQSYKYFKDWRLICSLAYNNVFDLHEIYNKEKTDINIDEMMRLACRYDGNYTTIYYCFMLGADINQAMITSVMNLWDGNLFLCIDLGADVFEECMKIAIEDHNGVLESILSFKNYYSPDVSLLSLKTTDPEKINDLLDEDIYKSKNRLIYKSC
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-22R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: RIMM_BACFR
Sequence: MIKREDVYKIGLFNKPHGIHGELSFTFTDDIFDRADCDYLICRLDDIFVPFFIEEYRFRSDSTALVKLEGVDTAERARMFTNVEVYFPVKHAEEAGPGELSWDFFVGFRVEDVRHGALGKVTDVDTSTVNTLFVVDRDGDELLIPAQEELIAGIDQKHKIITVDLPEGLLSLDECDDEES
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXCR1_PANTR
Sequence: MSNITDPQMWDFDDLNFTGMPPTDEGYSPCRLETETLNKYVVIITYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
What is the function of this protein?
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NIFH_PROA2
Sequence: MRKIAIYGKGGIGKSTTTQNTVAGLAEMGNKVMVVGCDPKADSTRLLLGGLTQKTVLDTLREEGEDVELEDIIKEGYGASRCTESGGPEPGVGCAGRGIITSVNLLEQLGAYDDEWGLDYVFYDVLGDVVCGGFAMPIRDGKAQEIYIVVSGEMMAMYAANNICKGILKYADAGGVRLGGLICNSRKVDNEREMIEELARQLGTQMIHFVPRDNMVQRAEINRKTVIDFDPSHNQADEYRALATKIDQNEMFVIPKPLEIEELEKLLIDFGIAN
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: SEC17_SCHPO
Sequence: MIADPDQLMQKAAKKAQGTGGFALFGGGNKYDEASELFLDAANGYRLQKQGSAAGYAFEKAAEMQLKTDDKDDAASTYVEAFKSYRREKPSEAARVLQIAIELFTRRGNFRRAANYKMDLGDIFEQELQDTKAALGAYEDAGEWYSSDQADALANKAYLKAADLAGLCGEYSLAIRKFEQVARASVQNNLLKWSVKDYLLKAGLCYMANGDEIATRRALEHFLEIDPSFASTREYQLLKDLQDTIEASDANMFADKVFTYDQLSKLDSWKTTILLKIKSSIQEAEDDLT
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
What are the official names of this protein?
Probable vesicular-fusion protein sec17 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: HF101_ORYSJ
Sequence: MRNLRAAAPASFLAPPAPPLLLPPSTPTPRGAFSAKASPAAAAAQAHGWCPSPRRVGRLRRRAGAASSSVASVEDAKKDVLVALSQIIDPDFGTDIVSCGFVKDLEISEALEEVSFRLELTTPACPIKDMFEEKANEVVAALPWVKKVNVTMSAQPARPAYAGELPEGLQKISNIIAVSSCKGGVGKSTVAVNLAYTLAGMGARVGIFDADVFGPSLPTMVSPENRLLVMNPESRSILPTEYLGVKMVSFGFAGQGRAIMRGPMVSGVINQLLTTTDWGELDYLVIDMPPGTGDIHLTLCQVAPLTAAVIVTTPQKLAFIDVAKGVRMFSKLKVPCVAVVENMCYFDADGKRFYPFGQGSGAQVVQQFGIPHLFDLPIRPTLSASGDTGIPEVVADPQGDVAKTFQNLGVCVVQQCAKIRQQVSTAVSYDRSIRAIRVKVPDSDEEFLLHPATVRRNDRSAQSVDEWTGEQKVQYGDIPEDIEPEEIRPMGNYAVSITWPDGFSQIAPYDQLEMLERLVDVPRATTAAVSS
What is the function of this protein?
Required for photosystem I (PSI) biosynthesis and assembly.  May serve as a chloroplast scaffold protein that specifically assembles iron-sulfur (4Fe-4S) clusters and transfers them to the chloroplast PSI and ferredoxin-thioredoxin (FTR) complexes.  Probably not required for assembly or stability of plastidic 2Fe-2S clusters (By similarity).
What are the official names of this protein?
Fe-S cluster assembly factor HCF101, chloroplastic, Protein HIGH CHLOROPHYLL FLUORESCENCE 101 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GLGA_LEPBP
Sequence: MKILHASAEYFPYTKMGGLADMLASLTKEQSRTEEVYVALPLIGKLGKEPNWTGKEVGALLPQDAKEETIAVSLLAKARFREAIESGVKLYFFDSELFSGLNSIYGQADEHYRFAIFSYACYALSQILQVDVFHAHDWHTALSLTLQKNSTKPIPSLFTIHNLAYQGDHPFWMTGFLKEDPFYLITSPFDQDGKCNYMKAGILSAGQITTVSPGYREETLREPNGFGLSYVLKKRKADYTGILNGIDPDEWNPKVDKRIFQTYHLQNWKEGKRKNKEHLYREIGRPNVSLDLPLIGLIGRLTYQKGFPTFLQAFLERRHLPHRYVVLGSGDPETENAFFHLSDMMPDVFYFYKGYNESLAHQIEAASDFFLMPSLFEPCGLNQMYSHVYGTIPIVSRVGGLRDTVDESIDIQFKTGIVFEPNDKSSLGYALERANDLFVSPERDHVVKNMMNLDWTWTKRKLEYDRVYKIAIELLE
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: AROC_YERPP
Sequence: MAGNSIGQFFRVTTFGESHGIALGCIIDGVPPGIPITEADIQLDLDRRRPGTSRYTTQRRELDQVRILSGVFEGVTTGTSIGLMIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLAQKFGVQVRGYLAQMGDVSCDLLDWDLVEQNPFFCPDASKLEPLDALMRELKKAGDSIGAKITVVAENVPVGLGEPVFDRLDADLAHALMSINAVKGVEIGDGFAVVTKRGSENRDEITPQGFQSNHAGGILGGISSGQPVVAHIALKPTSSIMVPGQTINRQGEAVEMVTRGRHDPCVGIRAVPIAEAMMAIVLMDHLLRQRAQCGDVASDVPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SEM1_HUMAN
Sequence: MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair (PubMed:15117943).  Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, SEM1, and either centrin CETN2 or CETN3 (PubMed:22307388).  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and thus transcription-associated genomic instability.  R-loop accumulation increases in SEM1-depleted cells.
What are the official names of this protein?
26S proteasome complex subunit SEM1, 26S proteasome complex subunit DSS1, Deleted in split hand/split foot protein 1, Split hand/foot deleted protein 1, Split hand/foot malformation type 1 protein.
What is the protein family that this protein belongs to?
Belongs to the DSS1/SEM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_BRUA1
Sequence: MRLILLGPPGAGKGTQAGLLTKKHGIPQLSTGDMLRAAVAQQSEIGKRAKAVMDAGQLVSDEIVNQIVSERIDAPDCANGFILDGYPRTVPQAQALSQMLSGKGLKLDAVIELKVDENALVKRMESRVAETIAKGGQVRSDDNPEAFRKRLVEYREKTAPLSSYYAGTGELRIINGMAPVEEVTAEIERILVPA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBEAG_DHBV3
Sequence: MWNLRITPLSFGAACQGIFTSTLLLSCVTVPLVCTIVYDSCLYMDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWRSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAEALRAVIPPTTTPVPQGYLIQHDEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPERYRGRDAPTIEAITRPIQVAQGGRKTTSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPTPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: IORA_THEKO
Sequence: MAKVTDIVLWDKPGERVLLLGNHAIARGALEANIAVFAAYPGTPSSELTDTMAAVAKKAGVYMEYSTNEKVAFETALAAAWSGLRAMTAMKHVGLNVAADSFLSSVGMGVEGGFVIMVADDPSMWSSQNEQDTRVYAKFANVPVLEPSSPHEAKEMTKYAFELSEKFKHFVILRTTTRSSHARGDVVLGELPEEIKTGKRKFGKFKKDPTRFVDVPAHARKFHPLILEKIEKIREELNNCPFNWIEGKEDAKVGIIAPGLSYAYVKEALAWLGVEDVKILKLGTPFPVPYGLLGKFFDGLEKVLIVEELEPVVEEQVKTWAYDKGLRIPIHGKDLVPRVYEMTTRRAVEAIAKFLGLETPINFAEIDEKYEKVSQIVPPRPPSLCPACPHRNSFFAIRKAAGPKAIYPSDIGCYTLGVLPPLRTVDTTVAMGASIGIGHGLSIAMNGSLAEEEHKEGKEKQIIVATIGDSTFYHTGLPALANAIYNRSNVLIVVLDNLVTAMTGDQPNPGTGQTPHGMGKRIPIEDVAKAMGADFVAVVDPYDIKATYETIKKALEVEGVSVVVSRQVCALYKIGQMRRRGMKWPIYHVVEDKCTGCKICINAYGCPAIYWDPETKKAKVDPTMCWGCGGCAQVCPFDAFEPMKEGE
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorA, IOR, Indolepyruvate ferredoxin oxidoreductase subunit alpha.
Protein: NUP57_YEAST
Sequence: MFGFSGSNNGFGNKPAGSTGFSFGQNNNNTNTQPSASGFGFGGSQPNSGTATTGGFGANQATNTFGSNQQSSTGGGLFGNKPALGSLGSSSTTASGTTATGTGLFGQQTAQPQQSTIGGGLFGNKPTTTTGGLFGNSAQNNSTTSGGLFGNKVGSTGSLMGGNSTQNTSNMNAGGLFGAKPQNTTATTGGLFGSKPQGSTTNGGLFGSGTQNNNTLGGGGLFGQSQQPQTNTAPGLGNTVSTQPSFAWSKPSTGSNLQQQQQQQIQVPLQQTQAIAQQQQLSNYPQQIQEQVLKCKESWDPNTTKTKLRAFVYNKVNETEAILYTKPGHVLQEEWDQAMEKKPSPQTIPIQIYGFEGLNQRNQVQTENVAQARIILNHILEKSTQLQQKHELDTASRILKAQSRNVEIEKRILKLGTQLATLKNRGLPLGIAEEKMWSQFQTLLQRSEDPAGLGKTNELWARLAILKERAKNISSQLDSKLMVFNDDTKNQDSMSKGTGEESNDRINKIVEILTNQQRGITYLNEVLEKDAAIVKKYKNKT
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  NUP57 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, and pre-ribosome transport.
What are the official names of this protein?
Nucleoporin NUP57, Nuclear pore protein NUP57.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin GLFG family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: TRMB_STRPI
Sequence: MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.