PharMolix/UniProtQA huggingface dataset:
Protein: LIPG_MOUSE
Sequence: MWLLLVTSVLSAFGGAHGLFGKLGPKNPEANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWITNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLKVIFGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADPQDVAMLLPKLPNLLYHKEILPYNHLDFIWAMDAPQEVYNEIVTMMAED
What is the function of this protein?
Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol (By similarity).  Shows a preferential hydrolysis at the sn-3 position of triacylglycerol (By similarity).
What are the official names of this protein?
Gastric triacylglycerol lipase, GL, Gastric lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGB1_RHIEC
Sequence: MKTPKTLPEVTLSWEISADEITAILAGSHSNPFAVLGVHQGGDAFVARCFIPGAEEVTAMTLDGGFIGELKQLHADGVFAGPVSLAKLQPVRYRARRGDAEWAVTDPYSFGPVLGPMDDYFAREGSHLRLFDKMGAHLIKHEGAQGIHFAVWAPNAQRVSVVGDFNGWDGRRHVMRFRADSGIWEIFAPDVPLGVAYKFEIRGHDGVLLPLKADPFARRSELRPKTASIAAAELEQVWEDEAHLKHWRETDKRRQPISIYEVHAGSWQRRQDGTMLSWDELASSLIPYCVDMGFTHIEFLPITEHPYDPSWGYQTTGLYAPTARFGEPEGFARFVNGCHKVGIGVILDWVPAHFPTDEHGLGWFDGTALYEHEDPRKGFHPDWNTAIYNFGRTEVVSYLVNNALYWAEKFHLDGLRVDAVASMLYLDYSRKHGEWIPNEYGGNENLEAVRFLQDLNIRIYGQHSNVMTIAEESTSWPKVSQPVHEGGLGFGFKWNMGFMHDTLSYMKRDPVHRKHHHNELTFGLLYAYSENFVLPLSHDEVVHGKGSLIAKMPGDDWQKFANLRAYYAYMWGYPGKKLLFMGQEFAQWSEWSEAKSLDWNLLQYRMHEGMRRLVRDLNFTYRSKPALHERDCEGEGFEWLVADDHQNSVFAWLRKAPGQKPVAVITNFTPVYRENYTIRLPSAGRWREILNTDADIYGGSGKGNGGRVQAVDAGGDITCSITLPPLATIMLEPEN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 1, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 1, Alpha-(1->4)-glucan branching enzyme 1, Glycogen branching enzyme 1, BE 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PVK1_PERBR
Sequence: GASGLIPVMRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PerBr-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUC2_PANTR
Sequence: MIARRNPEPLRFLPDEARSLPPPKLTDPRLLYIGFLGYCSGLIDNLIRRRPVATAGLHRQLLYITAFFFAGYYLVKREDYLYAVRDREMFGYMKLHPEDFPEEDKKTYGEIFEKFHPIR
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C2, Complex I-B14.5b, CI-B14.5b, NADH-ubiquinone oxidoreductase subunit B14.5b.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: CP1A1_BALAC
Sequence: MFSVFGLSIPISATELLLASATFCLVFWVVRAWQPRVPKGLKSPPGPWSWPLIGHVLTLGKSPHLALSRLSQRYGDVLQIRIGCTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFTLVADGQSMTFNPDSGPVWAARRRLAQNALKSFSIASDPASSSSCYLEEHVSKESEYLIGKFQELMAGSGRFDPYRYVVVSVANVICAMCFGRRYDHESQVLLSVVGLSNEFGAVAASGNPADFIPILRYLPNTALDDFKDLNRRFYIFMQKMLKEHYKTFEKGRIRDITDSLIEHCQGKRLDENANIQLSDEKIVNVVMDLFGAGFDTVTTAISWSLMYLVTSPSVQKKIQEELDTVIGSARQPRLSDRPRLPYLEAFILETFRHSSFLPFTIPHSTTRDTSLNGFYIPKGRCVFVNQWQINHDQKLWDDPSAFWPERFLTADGTINKALSEKVILFGLGKRKCIGETIARWEVFLFLAILLQQVEFRVTPGVKVDMTPVYGLTMKHAHCEHFQAHMRS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions.  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation.  Catalyzes the epoxidation of double bonds of certain PUFA.  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system.  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer.  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: GTFA_STRAG
Sequence: MVVYNLNRGIGWASSGVEYAQAYRSEVFRKLGVEAKFIFTDMFQNENIEHLTRNIGFEDNEIIWLYTFFTDLTIAATSYSLQQLKESFSLPIDRTEKNGKIISFFFKGSSIVVTVMLNDESSNIVQRVEYLMGGKLVRKDYYSYTKMFSEYYAPEDIGPCLYQRTFYNEDGSVAYEENVDGENSIFKFKETILYSKEELVGYMLEKLQLTNSDLILLDRSTGIGQAVLRNKGNAKVAVVVHAEHYNVSATDETTILWNNYYDYQFSNADSIDAFITSTETQTKTLIDQFKKYLNIEPVVYTIPVGSLSKLQRKEWHERKAFSLLTCSRLASEKHIDWLINAVVEANKVIPELTFDIYGEGGERQKLQEIIAKNKANNYIRLMGHKNLSSVYKDYQVYLSGSTSEGFGLTLMEAIGSGLPIIGLDVPYGNQTFIENNLNGYLIPRETPDNPQQISTAFAQYIVALFNSKDICKKHEYSYRIASRFLNDKIIENWSFFLRRLLNDYTI
What is the function of this protein?
Required for polymorphic O-glycosylation of the serine-rich repeat protein Srr2.  Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues of Srr2.  Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat proteins, probably Srr2 in this organism.  The GtfA-GtfB (Gtf1-Gtf2 in this bacteria) complex adds GlcNAc from UDP-GlcNAc to Srr2 substrate.  This subunit has low glycosyltransferase activity; GtfB enhances glycosyltransferase activity in vitro.  Upon expression in S. parasanguis GtfA/GtfB restores expression of serine-rich repeat protein Fap1 and complements a biofilm formation defect.
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase GtfA subunit, Glycosyltransferase Gtf1, Glycosyltransferase GtfA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Cell membrane association requires GtfB.
Protein: MDTM_ECO57
Sequence: MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRKPVLITGALIFTLACAATMFTTSMTQFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFLFGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVKDPTEPRFIWRAVPIQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFTLFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLAGLLNRVRQHQAAELAEEQ
What is the function of this protein?
Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP.
What are the official names of this protein?
Multidrug resistance protein MdtM.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANB_KLEP3
Sequence: MKPTTIALLQKCKQEKKRFATITAYDHSFAKLFADEGINVLLVGDSLGMTVQGHDSTLPVTVEDIAYHTRAVRRGAPNSLLLADLPFMAYATPEQTFENAAIVMRAGANMVKLEGGAWLADTVKMLAERAVPVCGHLGLTPQSVNVFGGYKVQGRGDAAQTLFDDALALEAAGAQLLVLECVPVELAKRITDALTIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDIRAAVRQYIAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_ECO7I
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: GFRA2_BOVIN
Sequence: MILANAFCLFFFLDETLRSLASPSSPQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTARLSDIFRLASIFSGTGADPAVSTKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYQTLTSCPTDNYQACLGSYAGMIGFDITPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLKDFTENPCLRNAIQAFGNGTDVNLSPKSPPFQATQAPRVDKTPSLPDDLSDSTSLGTSVISTCTSVQDQGLKANNSKELSMCFTELTTNIIPGSKRVIKPNSGPRRTRPSAALTAASFLMLKLAL
What is the function of this protein?
Receptor for neurturin.  Mediates the NRTN-induced autophosphorylation and activation of the RET receptor.  Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (By similarity).
What are the official names of this protein?
GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: METAA_CLOAB
Sequence: MPIKIPDNLPAAKTLNEENIFFMDEDRAYHQDIRPLNIVIVNLMPTKIVTETQILRLIGNSPLQVNPTFIHTQTHKSQNTSKEHLIKFYETFEEIKNNKFDGMIVTGAPVETLSFENVDYWEELCRIFDWSVTNVTSTIHICWGAQAGLYHHYGIPKYELHEKLFGVFKHNLTERNIKLTRGFDDEFYAPHSRHTYVKREDIKKNPSLKILAESDEAGAYIVASENGKNIFVMGHAEYDGDTLNLEYIRDKNQGMNIKIPKNYFKDNDPEKGPMVTWRGHANLLFSNWLNYYVYQETPFEL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPC_ASPFM
Sequence: MAMTMRSTRHASKLAQTARLALTNSRRYSTAEPDLKTALKAVIPAKRELFKQVKERSDEVIGEVKVANVIGGMRGLKSMLWEGSVLDPEEGIRFHGKTIKDCQKELPKGTSGTEMLPEAMFWLLLTGQVPSTNQVRAFSRELAEQSHLPQHILDLIKSFPRSMHPMTQLSIAVAALNTESKFAKAYEKGLSKADYWEPTFDDSISLLAKIPRVAALVFRPDEVDQVGTQALDASQDWSYNFAELLGKGGKENQDFHDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLLGLAGPLHGLAAQEVLRWILAMQDKIGTKFTDDDVRNYLWDTLKSGRVVPGYGHGVLRKPDPRFQALMDFAATRPDVLANPVFQLVKKNSEIAPAVLTEHGKTKNPHPNVDAASGVLFYHYGFQQPLYYTVTFGVSRALGPLVQLIWDRALGLPIERPKSINLLGLKK
What is the function of this protein?
Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate.  Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism.  Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.  May play a role in virulence.
What are the official names of this protein?
2-methylcitrate synthase, mitochondrial, Methylcitrate synthase, (2S,3S)-2-methylcitrate synthase, Citrate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TRUA_ECOK1
Sequence: MSDQQQPPVYKIALGIEYDGSRYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: COMD_METTH
Sequence: MKVDSSEAVYAGMKDAGIDFAVSVPCVNLRTVLEMVDADPAIMHVPVTREEEGFGVAAGAHMAGKTTAILMQNSGLGNSVNVLASLYSLYHIPITMIVSHRGTEGEFMEAQVPMGRATGDILRILEIPFRTPRSPAEARESIGELTDISLRTSKAVAVLLDVSYW
What is the function of this protein?
Involved in the biosynthesis of the coenzyme M (2-mercaptoethanesulfonic acid).  Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.
What are the official names of this protein?
Sulfopyruvate decarboxylase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ComD family.
Protein: NDK_ECO24
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_BURM1
Sequence: MRSIIADSKRLVVKVGSSLVTNDGKGLDHAAIGRWAAQIAALRAQGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFTEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDALIILTDQSGLFTADPRKDPAATLVAEANAGAPELEAMAGGAGSSLGRGGMLTKILAAKRAAHSGANTVIASGREPDVLVRLAGGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVEKLTAGGKSLLPIGVTDVQGAFARGEVIACVGPDGREVARGLTNYSSAETKLIHRKPSGEIESVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_SALA4
Sequence: MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PKS1_METAF
Sequence: MNHVTIKQSDTRADPFRVFIFGDQSSCNLSNLQLLLFKKSNVYLASFIDQVNLTLRHEVARLTAAERQSFPAFSSVQNLVARALKKDTSVALESTLATIYHLCCFINYFGDGQEAYPTGPTTHVSGLCIGALAAAAVSSSKSLAELVQAGIDAVRVSLKVGLLVARTAALFSHQESNGTSSSPWSYAVPDSQLPLALAEEAIESYQAKTNIPPLSLPYISAKGQNSWTVSGPPAIVQHFLETSQFEKTLRLTPLAVHAPYHAPHIFSAIDVQHIIRAVGPVSSFSSKLAFISSSSSRNLPTGLKFQDLLYRAVEDILILPLDLREAAENIRLVLEATDNVQQCALFPISTGVGPSLKQSFSSAMASRVSIVDCIMERVAADAGPKSTSGPKPSESKIAIIGMSGRFPESADVEAFWDLLHQGLDVHRPVPPDRFNGELYYDVTGKRKNTCKVMHGCWINDPGLFDAKFFNISPKEAEQSDPGQRLALATAYEALEAAGVVADRTPSTQRDRVGVFYGMTSDDYREVSCGQNVDTYFIPGGNRAFTPGKINYFFKYCGPSVSVDTACSSSLAAIHLACNSIWRNECDTAIAGGTNVMSNPDSFVGLDRGYFLSRTGNCHTFDDEADGYCRADAVGTVILKRLEDAIADHDPILGVISGALTNHSADAVSITRPHSGAQEEIFSKLLTESGVHPHQVSYIEMHGTGTQAGDATEMTSVLNCFAPSTSPRRLPHESLHLGSTKANVGHSESASGVSALIKVLLMMEKNIIPPHCGIKGKINHKFPTDLDERNVHIAKTATQWNRRNELNNIRRAFVNNFSAAGGNTALLVEDYPLLIADSSQQDARTAHVVTVSAKSIKSLKGNLENLKKFVQKQASTEGFLPKLSYTTTSRRMHHPFRVAIPAANSEQLLSALDEELKHDSYTCCSESPVAFVFSGQGSQYSSMGQHLLHFTIFRDEVHAYDILAQRHGFPSIMPLIDGSVDIEDLEPLVVQLGTVCVQMALASLWMALGMRPAYVVGHSLGHYAALKVAGVLTASDTIYLVAMRARLLQNKCSRGSHAMLAIRSSVAEIQAHLDEGIYDIACINGPQDTVVSGCIDDIDRLSQKLMDKGIKATRVNVPFAFHSAQVDPILDELEAIASQVEFHAPRVAVGCPLLGKTFKAGETPSLEAKHIRRHCRETVNFLDVLRSAKDDGFVSDKTAWIEIGPHTVCSNLVKANINQDITAVPSLMRNKDGWQVLASSVATLYRHGSSVAWDEYHHDFEACKQVLRLPAYSWDNKLYWIDYVHDWLLTRGDPPVQAAASLPAPPLTFSTASVHRIVHESVEKGKLTLTAECEFTNEQLREVVYGHVVNGNRVCSSSLYTDFGVTLGSYILEKYRPDLQGHAVDVQDMVVNKALVHKEGPTMLLRIDVVLDTTDSKAASMSIYSVNSKGNKTADHAQSSLHFEQPKVWLKSWDSTQYYVERSIEWLKEKADQGLNSRMSSGVIYKLFSSLVDYSTAYKGMQEAIVNTEDFEATALVRFQVDEGNFRCNPMWVDSCGQLAGFLMNGHAKTPKDQVFINHGWQYFRTVRKFSRDKTYRTYVRMRCVEGTTYAGDVYIFDDEGIVGVCGSITFQGIPRKVLNTAMPPPKSQNEAPVRSGPAKPAAKPPRSASSEHSGHFARHANIEPLKLDAALKSATTARNPMLPVFKIVAEEIGIPSASVDNGLVFADYGVDSLLSLSISGRLREELDLDVESSAFETCATLADLAAHLGLDTFSSDQSSGQSSSFGGLSPRSDSIGEITSSVTTPPSLSPRSSVSGSQCKDVCAILAEEIGVSMGEITNDTDLGALGMDSLMSLAVLSRLREELELDLEGDFFVSHPNFSSFKHMFQQGHGDEVGPEPSAELKQYRATSTLLQGSPKSALYTLFLLPDGSGSSFSYAPINAVRKDVCVFGLNCPWLKSAEKLVQFGLKGLATLYVEEIRRRAPHGPYNLGGWSAGGICAYEAAIQFTREGETVERLILLDSPNPIGLEKLPARLFDFVNGLGLFGDGKAPDWLLAHFLAFIDALDEWKPVPWDKALGGNSPPPMTYILWAEDGICKGTDARPEYRDDDPREMKWLLENRTNFGGNNWDVLLGQQSLSIERIQDANHFTMLRKGKNTERVAAFIRSTFG
What is the function of this protein?
Polyketide synthase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).  The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (By similarity).  The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (PubMed:20382249).
What are the official names of this protein?
Polyketide synthase 1, Conidial pigment biosynthesis polyketide synthase.
Protein: CENPM_BOVIN
Sequence: MSALRPLDKLPGLNTATILLVGTEDALLQQLADSMLKADCTSELKVHLARSLPLPCSVNRPRIDLIVFVVNLHSKLSLQSVEESLCHLDAAFFLGKVAFLATGAGRDSHCSIHRNTVVKLAHTYRSPLLFCDLEIEDFRAAMAQRLVRLLQICAGHVPGVSALNLLSLMRGSENPSLEDL
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity).
What are the official names of this protein?
Centromere protein M, CENP-M.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells. Localizes in the kinetochore domain of centromeres (By similarity).
Protein: NUOK_RHOPS
Sequence: MTGSDLIAMMILAAGLFAIGLFGVLARRGIMFQLVALEVALSGPALGFVAAGAYHADPQGQGMFILVLTLAAAEVAVGLALFLRIRRIAGSDDSDVISGMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL19_RICTY
Sequence: MNIIDNFEQENISKLTANKKIPDFEAGDTVKVTVKIIDKAIEKDGKEKLTERFQAYEGVVIAKRNRGITSSFLVRKISHGEGVERRFMTYSPIVHSIDVVKYGVVRRAKLYYLRHRNGKAARIRERHITSAKPKAVKS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MAP1_BUCAP
Sequence: MNCIIKTESEIKKMKVSGKIAAEVLEMIENYIKPNISTEEINNICHNFIIKKKAVSACLGYHGFPKSICISVNDVVCHGIPNKNQILKSGDIVNIDVTIIKKNYHADTSKMFLVGQTNILSQRLCKIAQESLYKSLNILKPGIPLYKIGEVIQNYVENNNFSVVKEYCGHGIGRAFHEEPYVLHYKNKSHVILEKGMIFTIEPMINAGSHEVKCMKDGWTVKTKDHSLSAQYEHTVLITENGCDILTWQKNEKIPSKFINK
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: YCGR_SALTY
Sequence: MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEYENSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVELNMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERANKVRE
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Overexpression of this gene decreases swimming and swarming motility; those cells that are motile turn predominantly counterclockwise.  The D-118 mutant is still able to bind FliM but no longer affects motility upon overexpression.  Binds 1 c-di-GMP dimer per subunit.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body. Note=Localization lost in FliM mutants E-155 or E-160.