PharMolix/UniProtQA huggingface dataset:
Protein: HLDE_HAEIN
Sequence: MAQYSAEFKQAKVLVLGDVMLDRYWFGATNRISPEAPVPVVRVQENEERAGGAANVAMNIASLNVPVQLMGLIGQDETGSALSLLLEKQKIDCNFVALETHPTITKLRILSRHQQLLRLDFEEDFNNVDCKDLLAKLESAVKNYGALILSDYGKGTLKDVQKMIQIARKANVPVLIDPKGTDFERYRGATLLTPNMSEFEAVVGKCNTEEEIIEKGLKLISDIELTALLVTRSEKGMTLLRPNQEPYHLPTVAKEVFDVTGAGDTVISVLATALADGRSFEESCYLANVAAGIVVGKLGTSTVSTVELENAIHARPETGFGIMSEAELKDAVAQAKARGEKIVMTNGCFDILHPGHISYLENARKLGDRLIVAVNSDDSVKRLKGESRPINNLENRMAVLAGLASVDWLVPFTEDTPQRLIGEILPDLLVKGGDYKPEEIAGSKEVWANGGDVKVLNFENGCSTTNVIEKIKLLKD
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: ALR_COXBR
Sequence: MNRATATINVTALKHNLSQIKALAPKSLAWAMIKSNGYGHGLVRVAKALSDANAFGVACIDEALTLREVGIKSPIIVMKGFYNEAELSQFARHRLGAVIHCSDQVSLLEKTNLTSSLSVWLKIDTGMNRLGFSVEQSPAVYNQLKTSSSIQKPIGLMTHLADADNENKTFTELQIKRFFSVTEKMIGPKSIVNSAGFFAYPNALVDWIRPGIILYGISPFGINYNSFKEKIEKKFRPVMTLSAKIIAIKNRRQNDSVGYGCTWSCSEDMPIAIVSIGYGDGYPRHAPSGTPVLLNGKICPLIGRVSMDMIAIDLRSQPNAQVGDDVILWGEGLPVEIIAEKAGTIAYELLCKITQRVQFIEIEK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: LPLA_KLEP3
Sequence: MSTLRLLLSDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDHVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTVSTAIVLAALNSLGVTAEASGRNDLVVKTDSGDRKVSGSAYRETIDRGFHHGTLLLNADLSRLANYLNPDQKKLQAKGITSVRGRVANLVELLPGITHQHICEAIQEAFFSHYGERVDAEVISPDNTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFRWGGVELHFDVEKGHITRTQAFTDSLNPAPLEALAARLVGCQYRAEVLLQQCEALVGDFPEQEAELKELSAWMAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJCP_BACSU
Sequence: MKKQKNNKKKNIEKRNIEKRNIEEKNNEDLEELENAIYTYHKKELLAFFLEKTRIGHDKEEYKRFQSLLYKLDIECLEFAISRFSHIDIIHDHSKYVPAFIPLFAAYLTMFFNFYEKHWGALSFAAGTIAAIVWIIAVERKHRNQAISIMKIFEQVKERKVKDRSKD
What are the official names of this protein?
Uncharacterized protein YjcP.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD59_CALSQ
Sequence: MGIQGGSVLFGLLLILAVFCHSGHSLQCYSCPYSTARCTTTTNCTSNLDSCLIAKAGLRVYYRCWKFEDCTFRQLSNQLSENELKYHCCRENLCNFNGILENGGTTLSKKTVLLLVTPFLAAAWSLHP
What is the function of this protein?
Potent inhibitor of the complement membrane attack complex (MAC) action.  Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity).
What are the official names of this protein?
CD59 glycoprotein, MAC-inhibitory protein, MAC-IP, Membrane attack complex inhibition factor, MACIF, Protectin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: COAX_MAGMM
Sequence: MLLVMDVGNTNIVLGLYEGDQLAHSWRIASRIERTGDEYGILLANLLQLKQVDAHGINGVILASVVPPIGSALVRAVRRYLGLETLVVGASMKYGLPLSEESPSGVGADRLVNAVAVFDKVAHAAIVVDFGTATTFDLIGEQGIYLGGAIAPGLNSSLDALFEKTAKLPRIELFHPERVIGKTTEEAMRSGLYWGYVGLVDGIIERMRVESGFANIHVTATGGLAKLIARDSRCIDDVDDMLTLTGLRLLYQRNR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_STRPS
Sequence: MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSSAGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ENGB_MYCCT
Sequence: MIKQASFITSAANKSNWINDDVSEICLIGRSNVGKSSFINSLTNNNKLAKISNTPGKTRLLNFFEINKGEYRLVDAPGYGYAKVDDSIKIQFAKMMEEYFINRKNLKGVFLLLDLRHKPSNDDIMMYQFLKHYNIPVVIIGTKLDKLKKNEYIKNEKMIKEAINFYQEDDFIKISNLNKTNIIKCYELINKLLGSK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: END4_UREU1
Sequence: MDKYNLIIGSHVSLKANDFFYGSVKEALSYGANTLMVYTGAPQNTRRQPIELFKINEAHNLLKEHNIDLNNLIVHAPYIINPCSSKKYVRELAKEFLIQEIERTQFMGITKIVLHPGSCLDQDEDIALKQVYTMLNEIFATINTNVVVCLETMSGKGSEIGINLKQLKTIIDNVDSKKNIGVCLDTCHMSDSGIALDHDSFNQYLKEFDAQIGIDYIKVLHINDSKNPRGANKDRHENLGYGTIGFDNLINIIYHPLLNNIPKILETPWFDFHDQSISLYEYEIKMIRDRKWFDIKYKLLVGNK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL22_BORPD
Sequence: METTAIIRGVHISAQKTRLVADLIRGKSVAQALNILTFSPKKAAGILKKAVESAIANAEHNDGADIDELKITTIFVDKAQSMKRFSARAKGRGNRIEKQTCHITVKVGA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RK33_CRUWA
Sequence: MAKGKDVRVTIILECTSCVRNDIKKESAGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYOB_ECO57
Sequence: MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN
What is the function of this protein?
Cytochrome bo(3) ubiquinol oxidase is the terminal enzyme in the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Catalyzes the four-electron reduction of O2 to water, using a ubiquinol as a membrane soluble electron donor for molecular oxygen reduction; ubiquinol-8 is the natural substrate for E. coli.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron and generating a proton motive force.  All the redox centers of this enzyme complex are located within the largest subunit, subunit I.  Protons are probably pumped via D- and K- channels found in this subunit.
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 1, Cytochrome o ubiquinol oxidase subunit 1, Cytochrome o subunit 1, Oxidase bo(3) subunit 1, Ubiquinol oxidase chain A, Ubiquinol oxidase polypeptide I, Ubiquinol oxidase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUCC_CAMJR
Sequence: MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENPAEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFGGIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TIG_PHOPR
Sequence: MQVTVETTEGLERHLTITVPAANIENAVTAELKKIAKNRRFDGFRPGKAPMKMVARMFGGSVRQDILGEVMQRHFIEAIVKEKINPAGAPTFTPVDIAEGKDLVFKASFEVFPEIVLAGLDQIAVEKPAVEVKDEDVTNMLDTLRKQQATWSDVDAAAEADSRVTIDFIGSIDGEEFEGGKAEGFALAMGQNRMIPGFEDSIVGKKAGEEFTLEVTFPEEYHAENLKGKAASFAITLHKVEAQELPELTEEFIAKFGVLDGSIEGLKTEVRKNMERELKQAVKGRIKEQVLDGLVEQNDINVPAALIDQEINVLRQQAAQRFGGDAKNTPELPRELFEEQAKRRVVVGLLIGEVIKTEELKADEDRVKAIITEMASAYEDPTEVVSYYEQNEKMMSNMRNVALEEQAIDALLAKAQVTEKEVGFNDLMNQPAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MURC_SALAR
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSDDADVRVEDYQQIGPQGHFTLLRQGMPDLRVTLNAPGRHNALNATAAVAVATEEGIDDDAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYDDFANVLTQVDALLMLDVYPAGETPIPGADSRSLCRTIRNRGKIDPILVSDPAQIATILAPVLTGNDLILVQGAGNVGKIARYLSEIKLKPQTQEEEQHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1023_LACGA
Sequence: MKRLWVTGYRSYELSIFSDKDPKLTVIKYALTNYFKSLLEEGKIDWIISGANLGIEQWALEAAIQLQNEYSVHTALMTPYLEFSKRWNENNQMKYQNLTEQVDFTASTSNYPYMSPAQLKNYQSFMLEHTDRAVLIYDPEHPGKPKYDYEAIQKYQEGHEYPVDIIDFYDLQESAEEYEENHRQENNFY
What are the official names of this protein?
UPF0398 protein LGAS_1023.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: TEFF2_HUMAN
Sequence: MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI
What is the function of this protein?
May be a survival factor for hippocampal and mesencephalic neurons.  The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
What are the official names of this protein?
Tomoregulin-2, TR-2, Hyperplastic polyposis protein 1, Transmembrane protein with EGF-like and two follistatin-like domains.
What is the protein family that this protein belongs to?
Belongs to the tomoregulin family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: METK_STAAT
Sequence: MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNPC3_RAT
Sequence: MAEDPQGGGAGGPQHPVPSGSHSSFPEYELPELHTRVFHVGAFGELWRGRLGAQDLSLNEPQAAAQPTDGEASNNGFEDAAVAEDLGCSLEAAAELRVVCGLDKLRCLGEDEDPEVIPENTDLVTLCVRKGLLDYREENITIDRACRQETFAYEMESHALGKKPENPADMIEEGESILSVNILYPVIFNKHREHKPYQTVLVLGSQKLTELRDSICCVSDLQIGGEFSNAPDQAPEHISKDLYKSAFFYFEGTFYNDKRYPECRDLSRTIIEWSESHDRGYGKFQTARMEDFTFNDLNIKLGFPYLYCHQGDCEHVVVITDIRLVHHDDCLDRTLYPLLTKKHWLWTRKCFVCKMYTARWVTNNDTFAPEDPCFFCDVCFRMLHYDSEGNKLGEFLAYPYVDPGTFN
What is the function of this protein?
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes.  Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes.  Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).
What are the official names of this protein?
snRNA-activating protein complex subunit 3, SNAPc subunit 3, Small nuclear RNA-activating complex polypeptide 3.
What is the protein family that this protein belongs to?
Belongs to the SNAPC3/SRD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIRBL_HUMAN
Sequence: MPVPASWPHLPSPFLLMTLLLGRLTGVAGEEELQVIQPDKSISVAAGESATLHCTVTSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISNITPADAGTYYCVKFRKGSPDHVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQLTWLENGNVSRTETASTLTENKDGTYNWMSWLLVNVSAHRDDVKLTCQVEHDGQPAVSKSHDLKVSAHPKEQGSNTAPGPALASAAPLLIAFLLGPKVLLVVGVSVIYVYWKQKA
What is the function of this protein?
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.
What are the official names of this protein?
Signal-regulatory protein beta-1 isoform 3, SIRP-beta-1 isoform 3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL21_RICRO
Sequence: MFAVIKAGGKQYKVDRNSIIKVEKIDGELGSKIQFDQILMIGEYSKPSFIGTPIVKGAVVTAEITNQLKDNKIIVFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PEPC_HUMAN
Sequence: MKWMVVVLVCLQLLEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAA
What is the function of this protein?
Hydrolyzes a variety of proteins.
What are the official names of this protein?
Gastricsin, Pepsinogen C.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: VPS74_ASHGO
Sequence: MSLQRRRVNKTAGNETVGGASLNRSDEEEGMTHKVAYDPEEQKLRENTREPTLTLMEEVLLMGLKDKEGYLSFLNENISYALRGCILIELALRGRIQVVDDAMRRRFDPSERLIEVVDGSKTGEALLDEALTLMKGSEPLTIVNWMDLLSGETWNFLKINYQLRQVRERLAKGLVDKGVLRTEMKNFFLFDMPTHPVADTSCKESIKRRILSVLVPRNVELQYTELFPETVAFKYLRTIALICSAHGANVLEKVLSTLDYEKRDRGFSRAEELLVQFSQYPFALDKDIETGISVNLNRLVQEELDRNPGTALNLEVVAGVLKVYSRMDDLL
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi.  Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus.  May also bind to the coatomer to regulate Golgi membrane trafficking.  May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.  Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains.  Involved in vacuolar protein sorting (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 74.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
Protein: LPXK_XANCP
Sequence: MSKRGARTPGYWYDNTPIPLPARMLAPVYGAVTAVRRSLYRRGWLKRHGVPVPVVVIGNVTAGGTGKTPLTITLVSRLQQAGWTPGVASRGYGRDDAGTARWVDADTPVALGGDEPVLIAWKTGARVRVDTDRLAAARALVEAGCDIIVCDDGLQHYRLARDVEIEVVDGQRRYGNGRMLPAGPLREPAARARECDFRVVNLGQGSDAVIPVVGTPVADTDAGFGEWQMRLSIDSVQPMDGKRARPLASLAGQRVHAVAGIAHPERFFAMLRARGIGVVPHAFPDHHVYRAQDFSFGSRLPVLMTEKDAVKCRPFADEWLYSVPLKAELPAAFWVSLLDRLDKLASRHSDA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: NU6M_PTYAL
Sequence: MTYFVLFLGLCFVLGGLAVASNPSPYYGVVGLVLASVAGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWGVVGYGVGFVVVLVVGLVVGGFVGDLDFGVVTVDSVGMFSVRLDFSGVAMFYSCGVGMFLVAGWGLLLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: YDCY_ECOLI
Sequence: MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQQQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL
What are the official names of this protein?
Uncharacterized protein YdcY.
Protein: GMHBB_ECOL6
Sequence: MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKKMGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEEFRQVCDCRKPHPGMFLSARDYLHIDMAASYMVGDKLEDMQAAAAASVGTKVLVRTGKPITPEAENAADWVLNSLADLPQAIKKQQKPA
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOBD_ECODH
Sequence: MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DERI_PECAS
Sequence: MLSIAIGADSAAIDLKNTITDYLQQKGLTVTDYSYDPTGENPIYPDVAYTLAHAIKDGKHQRGILLCGTGIGMCIVANKVNGIRAAQCHDTYSAQRARKSNNAQVIALGARVIGPELAKEIIGAWLDAEFEGGGSAPKVEKIGYYEHQEKHQ
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the isomerization of D-erythrulose 4-phosphate to D-erythrose 4-phosphate.
What are the official names of this protein?
D-erythrulose-4-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RS14Z_METKA
Sequence: MARREFGKGARRCRRCGDTHGVIQKYGIMLCRQCFREVAEKMGFKKYN
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PPLA_MOUSE
Sequence: MEKVQYLTRSAIRRASTIEMPQQARQNLQNLFINFCLILICLLLICIIVMLL
What is the function of this protein?
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+).  Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2.  Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle.  The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.  ATP2A2 inhibition is alleviated by PLN phosphorylation (PubMed:22971924, PubMed:26816378).  Controls intracellular Ca(2+) levels in elongated spermatids.  May play a role in germ cell differentiation (PubMed:30733280).
What are the official names of this protein?
Cardiac phospholamban, PLB.
What is the protein family that this protein belongs to?
Belongs to the phospholamban family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Sarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein. Note=Colocalizes with HAX1 at the endoplasmic reticulum. Colocalizes with DMPK a the sarcoplasmic reticulum.