PharMolix/UniProtQA huggingface dataset:
Protein: NRTD_SYNE7
Sequence: MTAILPSTAATVNTGFLHFDCVGKTFPTPRGPYVAIEDVNLSVQQGEFICVIGHSGCGKSTLLNLVSGFSQPTSGGVYLDGQPIQEPGPDRMVVFQNYSLLPWKSARDNIALAVKAARPHLSTSEQRQVVDHHLELVGLTEAQHKRPDQLSGGMKQRVAIARALSIRPEVLILDEPFGALDAITKEELQEELLNIWEEARPTVLMITHDIDEALFLADRVVMMTNGPAATIGEVLEIPFDRPREREAVVEDPRYAQLRTEALDFLYRRFAHDDD
What is the function of this protein?
Part of the ABC transporter complex NrtABCD involved in nitrate uptake (PubMed:7767600, PubMed:8437564).  The complex is probably also involved in nitrite transport (PubMed:7767600).  Probably responsible for energy coupling to the transport system (PubMed:7767600).
What are the official names of this protein?
Nitrate import ATP-binding protein NrtD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1670_STAAC
Sequence: MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
What are the official names of this protein?
UPF0473 protein SACOL1670.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: ATPB_SOLTU
Sequence: MRINPTTSGSGVSTLEKKNPGRVVQIIGPVLDVAFPPGKMPNIYNALVVQGRDSVGQPINVACEVQQLLGNNRVRAVAMSATDGLTRGMAVIDTGAPIRVPVGGATLGRIFNVLGEPVDNLGPVDTSTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINKENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKDGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLLVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGTIDEATAKAMNLEMESNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NK1R_CAVPO
Sequence: MDNVLPVDSDLFPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPGRVVCMIEWPSHPDKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAADYEGLEMKSTRYFQTQGSVYKVSRLETTISTVVGAHEEDPEEGPKATPSSLDLTSNGSSRSNSKTVTESSSFYSNMLS
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide substance P.  It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
What are the official names of this protein?
Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROE_SALTY
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLGDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHATDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIEQLQQELLA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: DAPA_MYCPA
Sequence: MSTVGFDAPARLGTVLTAMVTPFAADGSLDTAAAARLANHLVDSGCDGLVVSGTTGESPTTTDDEKRELLRVVLEAVGDRARVIAGAGTYDTAHSVRLAKACAAEGAHGLLVVTPYYSKPPQRGLIAHFTAVADATELPVLLYDIPGRSVVPIESSTIRALASHPNIVGVKDAKADLHAGGQIIAETGLAYYSGDDALNLPWLAMGATGFISVISHVAANQLRELLSAFTSGDIATARKINATVTPLCDAMARLGGVTMSKAGLRLQGIDVGDPRLPQVPATPEQIEALTADMRAASVLR
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_STUS1
Sequence: MAIVKCKPTSAGRRFVVKVVNQELHKGAPYAPLLEKKSKTGGRNNNGRITTRHIGGGHKQHYRLVDFRRNKDGIPAIVERIEYDPNRTAHIALLKYADGERRYIIAPKGVSAGDQLVSGINAPIKAGNSLPLRNIPLGSTVHGIELKPGKGAQLVRSAGASAQLVAREGSYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGAKRWKGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGFPTKGAKTRTNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL16_PHOPR
Sequence: MLQPKRTKFRKTFKGRNRGLANGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRHVKRQGQIWIRVFPDKPITSKPLEVRQGKGKGNVEYWVAQIQPGKVLYEMDGVPEVLAREAFNLAARKLPIKTTFVIKAVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL33_SHESR
Sequence: MAKAKGNREKIKLVSTAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: COAD_PELPB
Sequence: MKQKAIYPGTFDPFTNGHLDVLERALNIFEEVIVVIAENCQKHALFTIEEREAMTREVTCDYPGVTVEVLHRGLLADYARQVGARAIVRGVRQVKDFEYEFQMSLLNRQLYPEVTTVFLMPNVKYTYVASSIIKEVAMLGGDVSKFVHPCVLEMMHQKREEQN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACA_METAC
Sequence: MLFDYRKGGLFLGTISEKIFSRAAGTEAKANDFVLADVDYAMAHDGTSVLAVNAFKEMEMEKVWDPSRIVVPFDHIAPANNETSATLQREIREWVKEQGIPNFYEVGEGICHQVLPENGFALPGKLVVGADSHSCTYGAFGAFATGVGATDMAEIFATGKLWFKVPESFRMTVEGSLRKGVYAKDLTLYLIGKTGIAGATYKAVEFYGQAIRELTVAGRMTLCNMAIEMGAKTGIVPPDEKTFEFLKNRAAATYEPVYADPDAVYLEEFTYDADDIEPQVACPHQVDNVKPVGEVEGTHVDQVFIGTCTNGRLEDLEVAAAVLKGKQVAVRTIVIPASRTTLLAAIENGTMETLLKAGVTLATPGCGPCLGAHQGVLGEGEVCVSTANRNFKGRMGKGGFIYLASPATAAASALTGEITDPRTV
What is the function of this protein?
Component of a hydro-lyase with broad substrate specificity for cis-unsaturated tricarboxylic acids.  Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4-tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate).  Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)-aconitate.  These reactions are part of the biosynthesis pathway of coenzyme B.
What are the official names of this protein?
Probable methanogen homoaconitase large subunit, HACN, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: PMTE_ARATH
Sequence: MGSKHNPPGNNRSRSTLSLLVVVGLCCFFYLLGAWQKSGFGKGDSIAMEITKQAQCTDIVTDLDFEPHHNTVKIPHKADPKPVSFKPCDVKLKDYTPCQEQDRAMKFPRENMIYRERHCPPDNEKLRCLVPAPKGYMTPFPWPKSRDYVHYANAPFKSLTVEKAGQNWVQFQGNVFKFPGGGTMFPQGADAYIEELASVIPIKDGSVRTALDTGCGVASWGAYMLKRNVLTMSFAPRDNHEAQVQFALERGVPAIIAVLGSILLPYPARAFDMAQCSRCLIPWTANEGTYLMEVDRVLRPGGYWVLSGPPINWKTWHKTWNRTKAELNAEQKRIEGIAESLCWEKKYEKGDIAIFRKKINDRSCDRSTPVDTCKRKDTDDVWYKEIETCVTPFPKVSNEEEVAGGKLKKFPERLFAVPPSISKGLINGVDEESYQEDINLWKKRVTGYKRINRLIGSTRYRNVMDMNAGLGGFAAALESPKSWVMNVIPTINKNTLSVVYERGLIGIYHDWCEGFSTYPRTYDFIHASGVFSLYQHSCKLEDILLETDRILRPEGIVIFRDEVDVLNDVRKIVDGMRWDTKLMDHEDGPLVPEKILVATKQYWVAGDDGNNSPSSSNSEEE
What are the official names of this protein?
Probable methyltransferase PMT14.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: EFUD_HORCR
Sequence: MDPAKELIRITARAFYSTEHVLIIDALAIHSTLNDIDLAHILGMQLKGLRRLVGRLKEDGLISVESRGEKKEGAPPMTTLGKDGQPTSIKERLFYRDWYYLNYHRAIDSIKYRMMKLSKYIESQGAPTTEKKDLVCPRCKSQYTELEVMDNISPMGDFLCHMCQHSLDPATEDDTGENENMKRLNDQLSRIVDIMRNIDSTDVPENDFDTALSHALPIDRGSSNPARRIEIVESKPSIASTKGLSTAPDQISVSVMEDGDGVKIDPEELARRREKEAKQNMLPEWISKSTISGDITSVGAKEAAERASRDAHNMGLRVEDVAEDKKLRTDDDGAMDSYWAALKAEQERQAQQDQDEEEEEEDDDDDEFEDVDVGTASAQPASVPAISVSTPATSAQVSSTATDEDGPAAKRTKVTEAQSNGTAPAAAASSQAAAAESKNGESDEDEDELEFEDI
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  Is possibly responsible for the transcription regulation of one or more genes within the gene cluster (Probable).
What are the official names of this protein?
Transcription factor efuD, Enfumafungin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the TFIIE alpha subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF3_YERPN
Sequence: MSPSEYALEVAKRRTFAIISHPDAGKTTITEKVLLFGHAIQTAGTVKGRGSSHHAKSDWMEMEKQRGISITTSVMQFPYGGCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDREIRDPMEVLDEVERELNIACSPITWPIGCGKSFKGVYHLHKDETYLYQSGKGHTIQEVRIVKGLNNPDLDVAVGEDLAKQFRQELELVQGASHEFDHEAFLSGDLTPVFFGTALGNFGVDHMLDGLVEWAPAPMPRKTDTRVVVASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGRFEKGMKLRQVRTKKDVVISDALTFMAGDRSHVEEAYAGDIIGLHNHGTIQIGDTFTQGEDMKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLSNNDLIVGAVGVLQFEVVSSRLKSEYNVEAVYESVNVSTARWVECHDVKKFEEFKRKNELNLALDGGDNLSYIAPTMVNLNITQERYPDVIFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_BARHE
Sequence: MNHPDIARRVYNHTWKLDPIIRSLLDTDFYKLLMVQMIWGLYPNVNVTFSLINRSKTIRLADDIDEMELRAQLDHALNLRFTKKEMIWLAGNTFYGRKQIFEPDFLQWLENFQLPEYELTRKDGQYILHFHGPWTHSSMWEIPALSIISELRSRAAMKKLDRFTLDVLYARAKAKMWSKVERLKKLPNIKISDFGTRRRHSFLWQRWCVEALKEGIGNSFTGTSNVLLAMDTDLEALGTNAHELPMVIAALTNNDNELRKAPYQVLQDWNRYYGGNLLIVLPDTFGTEAFLRNAPDWVADWTGFRPDSAPPLEGGERIIQWWREKGKDPREKLLIFSDALDIDTIEKTYHHFHGKVRMSFGWGTDLTNDFVGCSPQETATFDALSLVCKVTHANGRPAVKLSDNPEKTIGNPQEIQRYLNFFGNENRVAKPIKT
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: REX_BACAC
Sequence: MEQQKIPQATAKRLPLYYRFIQNLSLSGKQRVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVNYLLSFFRETLDQDDITRVALIGVGNLGTAFLHYNFTKNNNTKIEMAFDVSEEKVGTEIGGIPVYHLDELEERLSSDIQVAILTVPATVAQSVADRLAETNVHGILNFTPARLNVSDNIRIHHIDLAVELQTLVYFLKNYPQ
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_MYCSM
Sequence: MSADITETPAWQALSDHHAEIGDRHLTELFADDPARGTELALTVGDLYIDYSKHRVTRRTLDLLVDLARAAGLEERRDAMFAGEHINTSEDRAVLHTALRLPRDAKLVVDGQDVVADVHDVLDRMGDFTDRLRSGEWTGATGERITTVVNIGIGGSDLGPVMVYDALRHYADAGISARFVSNVDPADLVAKLDGLEPAKTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVAKHSSRCPPTRSWSTKFGINTDNMFGFWDWVGGRYSVDSAIGLSVMAVIGKERFAEFLAGFHIVDEHFRTAPLHQNAPALLGLIGLWYSNFFGAQSRAVLPYSNDLSRFAAYLQQLTMESNGKSVRADGTPVSTDTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFSQPTDDLPTADGTGSMHDLLMSNFFAQTQVLAFGKTADAIASEGTPADVVPHKVMPGNRPTTSILATKLTPSVVGQLIALYEHQVFTEGVIWGIDSFDQWGVELGKTQAKALLPVLTGDKSPAAQSDTSTDALVRRYRTERGRPA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA714_ARATH
Sequence: MAIVYAVVARGTVVLAEFSAVTGNTGAVVRRILEKLSPEISDERLCFSQDRYIFHILRSDGLTFLCMANDTFGRRVPFSYLEEIHMRFMKNYGKVAHNAPAYAMNDEFSRVLHQQMEFFSSNPSVDTLNRVRGEVSEIRSVMVENIEKIMERGDRIELLVDKTATMQDSSFHFRKQSKRLRRALWMKNAKLLVLLTCLIVFLLYIIIASFCGGITLPSCRS
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Vesicle-associated membrane protein 714, AtVAMP714.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: CSL2_ONCKE
Sequence: TRVVTCDNGENVQFLICDSGVIFIERALYGRTDGTTCKEGRPANQLTNTQCSQTGTLEVLSHRCNGKQVCEVNTEVFRTSDPCVGIYKYLETTYTCLPATRSITCEGSDAPLECDEGTIQIHSANYGRRDQLVCSFNRPANQLANTNCLSQSITTSKSAERCNRKSQCDVPASNSLYGDPCVGTYKYLDVAYTCG
What is the function of this protein?
L-rhamnose binding lectin.  Has hemagglutinating activity towards rabbit erythrocytes and human type B erythrocytes.  Hemagglutinating activity is inhibited by smooth-type lipopolysaccharide (LPS) from S. flexneri 1A and E. coli K12, but not by rough-type LPS from S. flexneri, E. coli K12 and E. coli EH100.  Agglutinates E. coli K12 and B. subtilis.
What are the official names of this protein?
L-rhamnose-binding lectin CSL2.
Protein: WAC_DANRE
Sequence: MVMYARKQPRLGDGCTDRRDSQPYQTLKYSSKSHPDHRHEKMRDSNDATPPCKMLRRSDSPDNKHMDNTGHGRAKAIHPHRGREREGGTSISPQENSHNHSSLHSSNSHSNPNKSSDTPFEPADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEATKTAAVVNSFPKDRDYRREAMQATPASYSSTKSSIATEKPSSLTPSSSSAAVSGLDVPNSASSASGSTVPVSPVMQSPAPPTLLQDPSLLRQLLLALQTALQLNNASVDMAKINEVLTAAVTQASLQSILHKILTAGPSAFNITTLLSQATQLSNQVAQQSSQSPMSLTSDASSPRSYVSPRISTPQTNTASLKPPLSTTPVSSQTKINAMTVKSSSLPPPSSQQPLSTEKHHDNGNSPRTLQRQSSQRSPSPGPNHMGSNSSSSSNNGGGGGGQGPGVVSGAMPPGSVPPGTAPGRATCSFTPTLAAHFNENLIKHVQGWPAEHVEKQASRLREEAHTMGSIYMSENCTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
What is the function of this protein?
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1).  Positive regulator of amino acid starvation-induced autophagy.  Positively regulates MTOR activity.  May negatively regulate the ubiquitin proteasome pathway.
What are the official names of this protein?
WW domain-containing adapter protein with coiled-coil.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYW_THEKO
Sequence: MDDFKVTPWDVEGVVDYNKLIEQFGTSPLTDELIEKTAELTKSELPLFFRRRFFFSHRDYDKVLADYESGRGFFLYTGRGPSGPMHIGHIIPFFATKWLQENFDVNLYIQITDDEKFLFKEKLSFEDTKRWAYENILDIIAVGFDPDKTFIFQNSEFTKIYEMALPIAKKINFSMARAVFGFNEQSKIGMIFYPAIQAAPTFFEKKRCLIPAAIDQDPYWRLQRDFAESLGYYKTAAIHSKFVPGLTSLEGKMSASKPETAVYLTDDPEEAGKKIWKFALTGGQPTLKEQREKGGNPEKCVVFKWFEIFFEPDDEKLMERYRACKAGELTCGQCKRELIERVQKFLKEHQKKRKEAEKKVEKFKYTGELAQEQWDKAIPEPLRT
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX11_TITDI
Sequence: IGVAVECKDGYLMGSDGCKLDCLMKKGTYCADECSRVKGKDGYCYLWLACYCYNMPDSVKVWERATNRCGKGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Td11, T-beta* NaTx13.6.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TVA35_HUMAN
Sequence: MLLEHLLIILWMQLTWVSGQQLNQSPQSMFIQEGEDVSMNCTSSSIFNTWLWYKQEPGEGPVLLIALYKAGELTSNGRLTAQFGITRKDSFLNISASIPSDVGIYFCAGQ
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 35.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RLPA_AQUAE
Sequence: MERFLGFRTPLGALGVVILLTLILSSCSVKTSYKEKGRVYNGKCPEYAKVWVHYCPTKYAYTDRYQHLSKVKIVNPRNGKSVKISLRLNKKVRGICLPKRLKKYLGKPFLGKVYLLRCGENGVKKCPKYIRGYASWYGGKFHGRKTASGIRFNQHEYYAAHRYLPFGTLLEVKNLKNGRKVIVKVVDRGPYVRGRHLDLSYAAAKKLGMIRDGVIPFEAKVLRCGY
What is the function of this protein?
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
What are the official names of this protein?
Probable endolytic peptidoglycan transglycosylase RlpA.
What is the protein family that this protein belongs to?
Belongs to the RlpA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ERG27_YEAST
Sequence: MNRKVAIVTGTNSNLGLNIVFRLIETEDTNVRLTIVVTSRTLPRVQEVINQIKDFYNKSGRVEDLEIDFDYLLVDFTNMVSVLNAYYDINKKYRAINYLFVNAAQGIFDGIDWIGAVKEVFTNPLEAVTNPTYKIQLVGVKSKDDMGLIFQANVFGPYYFISKILPQLTRGKAYIVWISSIMSDPKYLSLNDIELLKTNASYEGSKRLVDLLHLATYKDLKKLGINQYVVQPGIFTSHSFSEYLNFFTYFGMLCLFYLARLLGSPWHNIDGYKAANAPVYVTRLANPNFEKQDVKYGSATSRDGMPYIKTQEIDPTGMSDVFAYIQKKKLEWDEKLKDQIVETRTPI
What is the function of this protein?
Facilitates the association of ERG7 with lipid particles preventing its digestion in the endoplasmic reticulum and the lipid particles.
What are the official names of this protein?
3-keto-steroid reductase ERG27, Ergosterol biosynthetic protein 27.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet.
Protein: KHSE_CALS4
Sequence: MDSDMSGGMVKVMVPASTANLGPGFDVLGVALNLYTEISMEFIKDGLEIFVEGEGVEDIENDQNNLIYKSAEVIFKKIGVFNKGLRIKIKNEIPLGRGLGSSAAAIVGGLLAANELTGRVLKREEILNLAALIEGHADNVTAALNGGLNVSIFDKNKVYYARKALEDDIDFLAFVPQEMVRTEIARKVLPEKVDFNDAVFNTGRTAFLVSVLIEKKYELLKIATQDMLHQKYRAKLVPFMEECFEKALLAGAYAAFLSGAGPTIMAISSPENSERVLKEVGKVYEERGLSYRAYRLKCENNGAQVLKTPSFV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK2_PACBA
Sequence: SPPFAPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-2, PK-2, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: METXS_PSEPG
Sequence: MSTVFPVDSVGLVVPQTARFDEPLALACGRSLASYELVYETYGTLNASASNAVLICHALSGHHHAAGYHAATDRKPGWWDSCIGPGKPIDTNRFFVVSLNNLGGCNGSTGPSSVNPATGKPYGADFPVLTVEDWVHSQVRLGERLGIQQWAAVVGGSLGGMQALQWTISYPERVRHCVDIASAPKLSAQNIAFNEVARQAILTDPEFHGGSFQDQGVIPKRGLMLARMVGHITYLSDDSMGEKFGRELKSDKLNYDFHSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAAAQGGDLAATLAHVTADYCIMSFTTDWRFSPARSREIVDALMAARKNVCYLEIDSPYGHDAFLIPTPRYMQGFSNYMNRIAI
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2579_BURO0
Sequence: MPSFDVVSEANMIEVKNAIEQSNKEISTRFDFKGSDARVEQKERELTLFADDDFKLGQVKDVLIGKLAKRNVDVRFLDYGKVEKIGGDKVKQVVTVKKGVTGDLAKKIVRLVKDSKIKVQASIQGDAVRISGTKRDDLQSTIAMLRKDVTDTPLDFNNFRD
What are the official names of this protein?
UPF0234 protein Bcenmc03_2579.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: GCSH_ECOLC
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.