PharMolix/UniProtQA huggingface dataset:
Protein: THII_PYRAE
Sequence: MEVVIIRVGELTVKRGLTRAEMERLLLRAAREAAEECGGARFEKEPGRIYAYGDVNCLKKALSKVFGVKSVSPARVITYQKITDIALEAADLWSGIVAGKRFAVRVHRVGEHAFTSREVAAEVGAVLVAAGGRVDLEDPELEFYIEIRGNRAYFYTEVIEGPGGLPLGSEGKVLALVSAGIDSPVAAWMLMRRGAHVDVLYCNLGGTITLRHALEVIKRLLAWSYGYNARVIIADCGPVARAMRRGVREELWNIAFKRALYRIGVEIAKRLGAIALATGESLGQVSSQTLQALAAVEAGIDMPILRPLIGMDKDEIVKHAQKIGTYELSAKLPEYCAVFSRRPRKWALREEVEAIDLALYDAITEVVNNAKIVRKRELDEFIKALTPPHDIEIDSAPEGAVIVDLRDEESYKKWHLPGAVRAGVDDVLALVDKLGRDKTYVFYCYSGGLSLDVAESLRKLGIKAYSLRRTRNAVPPSSQGERGN
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_NDVA
Sequence: MATFTDAEIDDLFETSGTIIDSIITAQGKPVETVGRSAIPQGKTKALSAAWEKHESIQPPASQDTPDRQNRSDKQPSTPEQMTPQNSPPATSTDQPPTQAAGEAGDTQLKTGASNSLLSMLDKLSNKSSNAKKGPWSSLQEGHHQLPTQQQGSQPSRGNSQERPQNRANAAPGDRGTDANTAYHGQWEESQLSAGATPHALRSGQSQDNTPASVDHVQLPVDFVQAMMSMMEAISQRVSKVDYQLDLILKQTSSIPMMRSEIQQLKTSVAVMEANLGMMKILDPGCANVSSLSDLRAVARSHPVLVSGPGDPSPYVTQGGEMTLNKLSQPVQHPSELIKPATVGGPDIGVEKDTVRALITSRPMHPSSSAKLLSKLDAAGSIEEIRKIKRLAVNG
What is the function of this protein?
This protein is probably a component of the active polymerase.  It may function in template binding.
What are the official names of this protein?
Phosphoprotein, Protein P, Non-structural protein C, 38 kDa/29 kDa.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus/avulavirus P protein family.
Protein: PRP19_HUMAN
Sequence: MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL
What is the function of this protein?
Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair.  Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154).  Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity.  During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3.  Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex (PubMed:20595234).  Recruited to RNA polymerase II C-terminal domain (CTD) and the pre-mRNA, it may also couple the transcriptional and spliceosomal machineries (PubMed:21536736).  The XAB2 complex, which contains PRPF19, is also involved in pre-mRNA splicing, transcription and transcription-coupled repair (PubMed:17981804).  Beside its role in pre-mRNA splicing PRPF19, as part of the PRP19-CDC5L complex, plays a role in the DNA damage response/DDR.  It is recruited to the sites of DNA damage by the RPA complex where PRPF19 directly ubiquitinates RPA1 and RPA2.  'Lys-63'-linked polyubiquitination of the RPA complex allows the recruitment of the ATR-ATRIP complex and the activation of ATR, a master regulator of the DNA damage response (PubMed:24332808).  May also play a role in DNA double-strand break (DSB) repair by recruiting the repair factor SETMAR to altered DNA (PubMed:18263876).  As part of the PSO4 complex may also be involved in the DNA interstrand cross-links/ICLs repair process (PubMed:16223718).  In addition, may also mediate 'Lys-48'-linked polyubiquitination of substrates and play a role in proteasomal degradation (PubMed:11435423).  May play a role in the biogenesis of lipid droplets (By similarity).  May play a role in neural differentiation possibly through its function as part of the spliceosome (By similarity).
What are the official names of this protein?
Pre-mRNA-processing factor 19, Nuclear matrix protein 200, PRP19/PSO4 homolog, hPso4, RING-type E3 ubiquitin transferase PRP19, Senescence evasion factor.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRP19 family.
Protein: TRMD_TROWT
Sequence: MFVMRCDFVSIFPEYFDVLDISLIGKARRNGLLDLRVHNLREYSEAGRVDSSPYGGGPGMVMSAEPWARAIEHIATGESLVVFPSPSGQPYSHDLAQSLSSEMHIVFCCGRYEGIDNRIYEWTATRLRSSGISIGDYVLNGGEIAALAILEGFVRFIPGVLGNPESLVEESYQYNLLEYPVYTKPAVWRGLEVPDILLSGNHDLIREWRYKKQLEITQKTRPDLYSTHIYETDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD11_DROME
Sequence: MAGATLFERAQALSSVNREEQDSSLLNKLVRDQEGAENDEERIRIKEQGILQQGELYKQEGKAKELADLIKVTRPFLSSISKAKAAKLVRSLVDMFLDMDAGTGIEVQLCKDCIEWAKQEKRTFLRQSLEARLIALYFDTALYTEALALGAQLLRELKKLDDKNLLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKVQGALDLQSGILHAADERDFKTAFSYFYEAFEGFDSVDSVKALTSLKYMLLCKIMLGQSDDVNQLVSGKLAITYSGRDIDAMKSVAEASHKRSLADFQAALKEYKKELAEDVIVQAHLGTLYDTMLEQNLCRIIEPYSRVQVAHVAESIQLPMPQVEKKLSQMILDKKFSGILDQGEGVLIVFEETPVDKTYERVLETIQSMGKVVDTLYQKAKKLS
What is the function of this protein?
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  In the complex, RPN6 is required for proteasome assembly (By similarity).  May act as linker between 19S regulatory subunit and the 20S proteasome core.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory complex subunit p42B, 26S proteasome regulatory subunit Rpn6.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
Protein: SSRP_GEOTN
Sequence: MPKGEGKVIAQNKKARHDYFIEETYEAGLVLQGTEIKSIRNGRVNLKDSFAKVEKGEVFLHNMHISPYEQGNRYNHDPLRTRKLLLHRREINKLIGYTKEQGYTLVPLKLYIKNGFAKVELGVAKGKKKYDKREDMKRKEAQREIERAFRERQKI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SECE_ECOLI
Sequence: MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFITGLRF
What is the function of this protein?
Essential subunit of the protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.  Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_MALP2
Sequence: MIKTTIIASIKDLIKDAVKDKFKITIDLNDFVVDKAKSIEFGDFYSNVAMILASKLKKNPILIAEEICEYLKNHKTNLFESTEAVKPGYINVFLSNSVKSDLFKQINKDKDTYGIFEPKKVAYNIEFVSANPTGSLHIGHARNAALGQTLGNVWKAYGYTIEQEYYINDGGNQINNLGMSVFYRYLQKCGKDVQMEEDFYQGSEPIAVAELIYKEHKDKFVNVKYSATKIEDEKVFDFFRDFSKTELMNIIKKDLKDFSVHFDRYFPESKIYEMKLVDPTIKKLGKYVYEKDGALWLKTTEFGDDKDRVIVKSDKSFTYFMPDIAYHDIKATRTINGLKTDKIFNIWGADHASYVDRMTVALQCLGFKKDIMHVIVMQMVKLTKNGKEFKMSKRSGNSLTLRDLINAIGVDNSRWELISQAAESHIEIDVEKFTSADSTSNLSYVLYAYSRIQKILEKNESLLKESKSYNTDLLTNLKEKDMIAMLFYYPQTIANIAKSYEVHKIPIFLYTLANLLHSYYSEVKIIDESNKELLIQRLHLLQCVNQVIKNGLKLLDIEAKVLNK
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_RHIWR
Sequence: MLGGLAKAIFGSSNDRYVKSLRPILQKIAGFEPTLEAMNDEELAAQTVKFRQRLDAGETLDSLLPEAFATVREAARRVLGQRHYDVQMIGGIVLHRGEIAEMRTGEGKTLVATLAVYLNALPGEGVHVVTVNDYLATRDAEWMGRVYRFLGLTVGVIVPNLSDQERRDAYGADITYGTNNEFGFDYLRDNMKYDRALMVHRPFNFAVVDEVDSVLIDEARTPLIISGPTDDKSELYMQVDAIVKQVTKDDYEFDEKQRSVVLTEDGTERIERLLEAAGLLEGGNLYAYENTQVVHHLNQALRANVAFKRDTDYIVKDEKIIIIDEFTGRMMDGRRWSDGLHQAVEAKEGVKIEPENQTLASITFQNYFRMYPKLGGMTGTAATEAHEFYQIYKMNVVTIPTNLPVKRIDQDDEFYKNMLDKFAAITQAIREAKERGQPVLVGTVSIEKSELLSEFLTKEKVEHKVLNARYHEQEAHIVAQAGRLGAVTIATNMAGRGTDIQLGGNLEFRMLDEHPALEIGTPEFDAAAERIRGEIIAEKEAVLAAGGLFVLGTERHESRRIDNQLRGRSGRQGDPGLSRFYLSLDDDLLRIFGPQTMFARMMNKNLADGEAIVSPWISKAIETAQKKVEARNYDIRKQVVEYDDVMNDQRKVIYEQRADIMDAETVDDVVTDMRADTANAIVGGCCPPHSYPEQWDVDTLKLRSAETLGITPPFDEWIEQDGIDPEILAEKVLAEADAVIAAKRATIDDQSWHGIEKSVLLQTLDHHWKEHLATLDALRQVIHLRAYAQKTPINEYKHEAFALFERMLVAIREEVTRVLAHVRFEMAPQDYAELPPMPDFVTEHVNALTGEDNSGDRDGGTLGIIGSRVPQAIAAPAGDDFEITPEIAATLGRNSLCPCGSGRKYKHCHGAL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ATPB_BURCM
Sequence: MSTAALVEGKIVQCIGAVIDVEFPRESMPKIYDALILDGSELTLEVQQQLGDGVVRTICLGASDGLRRGLTVKNTAKPISVPVGKPTLGRIMDVLGRPIDEAGPIESEVTRSIHQKAPAFDELSPSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHGGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEHFRDEGLDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKKGSITSVQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVIGEEHYSITRRVQQTLQRYKELRDIIAILGMDELSPEDKLSVARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVDGECDHLPEQAFYMVGTIDEAFEKAKKIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1020_LISMH
Sequence: MLTNEISENEKPREKLLNYGIESLSSSELVALIIETGTKNESVLTIANRIIMKFKNVAEMQYASIEEFQLVNGIGVAKASKIMAAIELGKRISIVTEQEEVVVRCPEDAVKLVMPELAFLFQEHFHCLFLNTKNQVIYRQTIFVGGLNASIVHPREVFRLALRKSAASIMCFHNHPSGDPAPSSEDLLVTKRLAEAGNIVGITLLDHIIIGKNKYISLKEKGYF
What are the official names of this protein?
UPF0758 protein LMHCC_1020.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RISB_DESVM
Sequence: MLHVKTIEGQFDAKGLKFAIIATRFNDFIVDRLVGGAVDYLARHGCEREDMTIVRIPGAFEMPIVAQKLAKSGRYHGIIALGAVIRGATPHFDFVAGEATKGLAHISLDSGVPVGFGLLTTDSIEQAIERAGTKAGNKGVEAAAAVLETVRVMEQL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DEOC_ECO57
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_SINMW
Sequence: MDKFVKLTGVAAPLPVVNIDTDMIIPKDYLKTIKRTGLGTGLFAEARYNEDGSPNPDFVLNKPAYQNAKILVAGDNFGCGSSREHAPWALLDFGIRCVISTSFADIFYNNCFKNGILPIVVSQEDLDKLMDDASRGSNAVLTIDLEALEITGPDGGSIKFEVDAFKRHCLLNGLDDIGLTLEKGRSIDNFEKATAASRPWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CBPT_THEVU
Sequence: MRKKWLSLSLVLVLIVACVPALGFSQNIENPSIFDLGIKLYKIDGVSTKEQRSAIASTGAAIEEVGKDYVKVLATPSEAKQIKQKGFTATVDTSLTTQDFPSYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQTNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVIGRETSRNKEAVLYVAEKADCPYSVIGKSCSTK
What is the function of this protein?
Able to split off hydrophobic and basic amino acids with comparable efficiency.
What are the official names of this protein?
Carboxypeptidase T.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
Protein: ESXG_MYCTU
Sequence: MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF
What is the function of this protein?
EsxG, in complex with EsxH, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth.  The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery.  EsxG stabilizes EsxH in the host cytosol.
What are the official names of this protein?
ESAT-6-like protein EsxG, Conserved protein TB9.8.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: SAU36_ARATH
Sequence: MRKIIGFRIGRRVSRWIFRKTRIQRSGYNRIHSTQQACMLMRPLAKLKSWGQRLKQSFRRRSTRRSAYIPVDHKKADPVPRGHLAIYVGQKDGDCHRVLVPIVYFNHPLFGELLREAEKEYGFCHEGGITIPCLYSDFERVKTRIASGSSSRVFPWGRHCRN
What is the function of this protein?
Acts a positive regulator of leaf senescence and may mediate auxin-induced leaf senescence (PubMed:23250625).  Plays a role in the regulation of seed germination by gibberellins and abscisic acid (ABA).  Plays a role in the regulation of light-dependent hypocotyl elongation (PubMed:23503980).
What are the official names of this protein?
Auxin-responsive protein SAUR36, Protein RESPONSE TO AUXINS AND GIBBERELLINS 1, Protein SENESCENCE-ASSOCIATED GENE 201, Protein SMALL AUXIN UP RNA 36.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
Protein: PYRB_LISW6
Sequence: MKNLLSMEALTVHEIEHLLEQAAQFKHGKKATFKEQTFAVNMFFEPSTRTHTSFEVAEKKLGVEVISFDASSSSMTKGETLYDTLLTMQAVGVNVAVIRHSDENYYAGLENLDIAIVNGGDGCGEHPSQSLLDLFTIKEQFGTFQGLKIAIVGDIRHSRVANSNMKVLKRLGAELFFSGPREWFDDSYLAYGTYLSIDEMVEKVDVMMLLRVQHERHSGTERFTKASYHEKFGLTEERAMKLKEDAIIMHPSPVNRDVEIADSLVESEKSRIVTQMTNGVFIRMAILEVILKEKSRRAKVCTY
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS17E_THEON
Sequence: MGNIRQTFIKRVARELFDRYPDQFTKDFEHNKKKVGELTNVTSKTIRNRIAGYITRLVRMKEEGKML
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: DEF1_CLOPE
Sequence: MAIRNLRFNDDEILRKKCRVVDDINDRIKVLVEDMIETMYENNGVGLASPQVGILKRIFVVDAMDGAGSRVFINPEILEKSGEQTDEEGCLSLPGRHKPVKRANKIKIKALDVNGNEFVLDAEGFLARAIQHEYDHLEGVLFIDHEL
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TGCE2_SCHPO
Sequence: MSGFNKNQIYWGDYVGVIAAFVGVYTELVARIFIYMIPERVREWFRVRIIVLYHYYISSKTTDGMTDAVQKCRNIYEICEAFGYRVEEHLVRTQDNFILCLHRITHPKQSQHKREVVYCHHGLMTNSELWVAVNESERSLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREKLNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFSNYFVDYIVKVNPKIMYHLFGRRCLLPSVTFWQNICYPPIFVKIVDVSLKILFNWDLSNISLNQKLCGYAHLYSFSSVKSVVHWLQIIKNCTFQLYDDDMALLAGYGSRHYQVPLFPTNNIKCPMLILWGGKDTLINMEVMRTALPPHAKEVSIAHYEHLDFLWGQDVKEEVFPVVIDALKHHSLGKAKHFVKQNGFH
What is the function of this protein?
Probable lipase.
What are the official names of this protein?
Probable lipase C16A3.12c.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole. Membrane; Single-pass type II membrane protein.
Protein: DNLJ_CELJU
Sequence: MSNLSLFDDVSAEIAQLREQIRYHNYRYYALDEPQIPDAEYDRLMQRLRELEAQYPASVTPDSPTQRVGAAPLSAFQTVEHQIPMLSLDNAFEEADVIAFNQRILDRLKSTENIEYACELKLDGLAVSLLYRDGVLVRGATRGDGSKGEDITQNLRTIASVPLKLLGEGYPAVLEVRGEVYMPKAGFNALNEKARSTGEKLFVNPRNAAAGALRQLDSRITASRPLEMCAYSVGLVEGGELPGTHTGILAALKSWGFLTNKETATASTIADCIAFYQSIQARRDSLAYDIDGIVFKVNARELQESLGFISRAPRWAIAYKFPAQEEMTVLQDVEFQVGRTGAVTPVARLQPVFVGGVTVSNATLHNRDEIQRLGIMIGDTVIVRRAGDVIPQIVQVVESRRPTDARPVLFPDHCPVCGSPVETLEDEAIARCSGGLVCAAQRKEAIKHFASRKALDVEGLGDKLVEQLVDTGLVSKLADIYQLTGEQLAAMERMGEKSADNLLQALEASKHTTLAKFIYALGIREIGEATARNLANHFGSLEKLAEADEETLVQVNDVGPVGAHFVAEFFAQESNRQAVADLRAAGIHWQDLDVSTIEDLPLKGLTYVLTGTLEVMSRDDAKAHLLALGAKVAGSVSAKTDYVVAGPGAGSKLQKARELNLNVMDEEALLDLLRKHGRLE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NDHJ_SACHY
Sequence: MQQGWLSNWLVKHDVVHRSLGFDHRGVETLQIKAGDWDSIAVILYVYGYNYLRSQCAYDVAPGGSLASVYHLTRIQYGIDNPEEVCIKVFAQKDNPRIPSVFWVWRSADFQERESYDMVGISYDNHPRLKRILMPESWIGWPLRKDYITPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FPG_NEIMA
Sequence: MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEILSGRQVLSCGRRAKYLIVRFQTGILLIHLGMSGSLRIFTPSDGRIGRSDRHDHVDIVFSDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCTDYLYVRLKAQKRAVKLALMDNAVVVGVGNIYANESLFRAGISPHRPANRLKKKECALLVETVKAVLRRAIETGGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPQCGGLVVKETLGQRGTFYCPNCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: AMPA_SHESH
Sequence: MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTIKTLNETGSMEAVCFLTELHVKGRDTYWKVREAVETTQNSLYSFDALKSAKGETRRPLRKLVFNVPTRRELTVGERAIEHGMAVSAGMRLCRDVANMPPNICNPAYLASQARQMGENSEELTVTTVGEEQMAKLGMNSYLAVGRGSDNESIMTVMEYKGAVDNTEKPIVLVGKGLTFDSGGISLKPGEGMDEMKYDMGGAAGVIGAMKALCDMKLPINVVAILAGCENMPSSNAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFDPELVVDTATLTGACVIALGKHASGLFSGHNPLAHELLNAGEQSGDRAWRLPIWDEYQEHLESPFADMTNLGGRPAGAITAACFLSRFTKKYNWAHIDVAGTAWNSGANKGSTGRPVPLLTQFLINRAGVEQGD
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.