PharMolix/UniProtQA huggingface dataset:
Protein: CH60_SHEPC
Sequence: MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGSPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKALSQPCADSKAIAQVATISANSDESIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELDHPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGEQAQIEARVSQIKQQIEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIAELEVLNEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNFGYNAGNDTYGDMLEMGILDPTKVTRCALQFAASIAGLMITTEAMVAEIPQNSAPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5059R_ASFM2
Sequence: MFSLQDLCRKNLFLPLEPLGKHVVQRLGLYWKGHGSLKQMGQCFVCIDQTWILSIHKALQIAASEGNEDIVKLLILWNGNLKYAIIGALEGRHYDLIQKYYNQIGDCHEILPLIQDPKIYERCHELNVTCTFQCLFQHAIKDNMLPILQKYGQDLNGNRRMVQLLYEMACRLQNYDIIKWIGFNLQVYNLEAIFSIAFVRKDLTLYSLGYMLLLNRMSTEDRNFISIITRHLEYASKKGLLDFVLESLKYGGQVDTVLFQAVKYNHRKILAHFIHHVPREIVEKLILHAVESRASRKTFNLLLSSINYCMNPFVKKLLHAVVKHKFMLIIKLLLERPKKKINLVNAALFKLVKYSTYPEIVKYMKEFSVNPEMVIKMAARLMRVDLIKKISKDAWENKLERIKHLKQMVHTMNHRNGKNLIMYNIYDITGYTYLNAKEAFNLTRFYAVHNATCLFKEMCKNCFVHDLIQLRELLEDCLHIANRHAYIQIAETANEYIKYIDDITPK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-9R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: PMA1_ORYSJ
Sequence: MGGLEEIKNEAVDLENIPIEEVFEQLKCTREGLSSEEGNRRIEMFGPNKLEEKKESKILKFLGFMWNPLSWVMEMAAIMAIALANGGGKPPDWEDFVGIIVLLVINSTISFIEENNAGNAAAALMANLAPKTKVLRDGRWGEQEAAILVPGDIISIKLGDIVPADARLLEGDPLKIDQSALTGESLPVTKNPGDEVFSGSTCKQGEIEAVVIATGVHTFFGKAAHLVDSTNQVGHFQTVLTAIGNFCICSIAVGIVIEIIVMFPIQHRAYRSGIENLLVLLIGGIPIAMPTVLSVTMAIGSHKLSQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLSVDKNLVEVFTKGVDKDHVLLLAARASRTENQDAIDAAMVGMLADPKEARAGIREVHFLPFNPVDKRTALTYIDADGNWHRASKGAPEQILTLCNCKEDVKRKVHAVIDKYAERGLRSLAVARQEVPEKSKESAGGPWQFVGLLPLFDPPRHDSAETIRKALHLGVNVKMITGDQLAIGKETGRRLGMGTNMYPSSALLGQNKDASLEALPVDELIEKADGFAGVFPEHKYEIVKRLQEKKHIVGMTGDGVNDAPALKKADIGIAVADATDAARSASDIVLTEPGLSVIISAVLTSRCIFQRMKNYTIYAVSITIRIVLGFLLIALIWKYDFSPFMVLIIAILNDGTIMTISKDRVKPSPLPDSWKLKEIFATGIVLGSYLALMTVIFFWAMHKTDFFTDKFGVRSIRNSEHEMMSALYLQVSIVSQALIFVTRSRSWSFIERPGLLLVTAFMLAQLVATFLAVYANWGFARIKGIGWGWAGVIWLYSIVFYFPLDIFKFFIRFVLSGRAWDNLLENKIAFTTKKDYGREEREAQWATAQRTLHGLQPPEVASNTLFNDKSSYRELSEIAEQAKRRAEIARLRELNTLKGHVESVVKLKGLDIDTIQQNYTV
What is the function of this protein?
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump.  The proton gradient it generates drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity).
What are the official names of this protein?
Plasma membrane ATPase, Proton pump.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASTC_ESCF3
Sequence: MSQPITRENFDEWMLPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDLNSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLIGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACERFVSGGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: HMDH_ASPTN
Sequence: MDPVVKKPSPGGVQHRVTKGLRAIVGHACRHPIHTLLVTALTAATTHLHVLEGTYQAAHRGLAPWAKETPLNVQSFLCGSRTVTLGEASAWRWQIDDRPKVSEDGQSDFHWALVTLDLPGASVDASIPFLSNTLSEFLGAEQITPTPDSSPSPDHSALTFRVPYSQLDGFLQAVEIIPSEKEDDSWRLRSPREEGSPTSLGHWVGSSWLSFLHRVKHAETVDLVIIGLSYLAMNMTVVSLFRVMRQLGSRFWLATSVLLSGAFAFVLGLGITTTCDVPVDMLLLFEGIPYLVLTVGFEKPIQLTRAVLCVSEELRGGWQRPVPNGASSDDSRQSQLIPNIIQLAVDREGWYIVRSYLLEIGALALGAVLRPNDSLGHFCFLAAWTLLIDAILLFTFYATILCVKLEITRIRSPGGLGQVNAKHPSGIFGHKVKSTNITWWKLLTVGGFVLCHFLQLSPFFYRVMGEYMANGTLPPTAVSPFKEAANGLNEIYLTARVEGFETRVTVLPPLQYALESAGFNISATKRSTFDGVLDGLESPLGRLCLMGALVVSLVLNNHLIHAARWHAWPQARESAVPDGSSLSVPCSATAPEVCTRPPEETEALLKSNQAESLTDDELVELCLRGKIAGYSLEKTLERIAAGSSCSVTRLDAFTRAVRIRRAAVSKTPSTQNLCSGLAESLLPYRDYNYELVHGACCENVVGYLPLPLGVAGPMVIDGQALFIPMATTEGVLVASASRGCKAINAGGGATTMLKGDGMTRGPCLRFPSAQRAAEAQRWVESPLGHEVLAAAFNATSRFARLQTLTVAQAGIYLYIRFRTTTGDAMGMNMISKGVEKALEAMAAEGGFPDMHTVTLSGNFCSDKKSAAINWIGGRGKSVIAEATIPAETVRQVLKTDVDALVELNTAKNLVGSAMAGSLGGFNAHASNLVQAVFLATGQDPAQNVESSSCITTMKNIDGNLHIAVSMPSMEVGTIGGGTILEAQGAMLDLLGVRGAHATEPGANARRLARIVAAAVLAGELSTCAALAAGHLVNAHMQHNRSAGATVKK
What is the function of this protein?
HMG-CoA reductase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (By similarity).  In this module, the cytosolic acetyl-CoA acetyltransferase catalyzes the formation of acetoacetyl-CoA (By similarity).  The hydroxymethylglutaryl-CoA synthase then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity).  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase (By similarity).
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LIPM_ANOFW
Sequence: MEKEVWRFIDSGNCSPAFNMALDEALLEWHSEGKIPPTIRFYGWNPPTLSIGYFQKVEKEIDMEAVKKYGLGFVRRPTGGRGVLHDQELTYSVIVSELHPAMPQTVTEAYRVISQGILEGFRFLGLDAYFAVPKTEEEKADLKNPRSAVCFDAPSWYELVVEGRKVAGSAQTRQKGVILQHGSILLHLDEDMLFSLFKYPNERVKERLRQNFKNKAVAINELTDRNITINEAKEAFFRGFEKGLNVQLERYELTDDELFYVQQLAKNKYETDEWNFKR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.
Protein: CYF_PELHO
Sequence: MQTRKTLSWIKEEITRSISLSLMLSIITHASLSNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQTVLPDTVFEAVVRIPYDMQIKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEMKEKIGNLPFQSYRPTQKNILVIGPVPGQKYSEIAFPILSPNPETNKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVSNATAAGIVSKIIRKERGGYEITIADASNGRQVVDIIPPGPELLVSEGESLKVDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLTSVLLAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BIOF_PARP8
Sequence: MQLLDTLEQGLKEIDARGLRRRRRTVDSPCSAHMTVDGRNMIGFASNDYLGLAAHPLLVAAITEGARRYGAGSGGSHLLGGHSRAHAQLEDDLAEFAGGFVDNPRALYFSTGYMANLATLTALAGRGTTLFSDSLNHASLIDGARLSRADIQIYPHADAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGAWLVVDDAHGFGVLGPQGRGAVAEAALRSPHLIVVGTLGKAAGVSGAFVVAHETVIEWLVQRARPYIFTTASVPSAAHAVSASLRIIGGDEGEHRRAHLRSLIALTRDMLKSTPWLPVDSHTAVQPLIIGSNEATLDVAASLDRANLWVPAIRPPTVPEGTSRLRISLSAAHSHNDLEQLEHALMKTAEARA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: CHCH7_HUMAN
Sequence: MPSVTQRLRDPDINPCLSESDASTRCLDENNYDRERCSTYFLRYKNCRRFWNSIVMQRRKNGVKPFMPTAAERDEILRAVGNMPY
What are the official names of this protein?
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the CHCHD7 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: OPDA_SALTY
Sequence: MTNPLLTSFSLPPFSAIKPEHVVPAVTKALADCRAAVEGVVAHGAPYSWENLCQPLAEADDVLGRIFSPISHLNSVKNSPELREAYEQTLPLLSEYSTWVGQHEGLYNAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLSELGNQYSNNVLDATMGWTKLITDEAELAGMPESALAAAKAQAEAKEQEGYLLTLDIPSYLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSPVMEEILALRHELAQLLGFENYAHESLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVEELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERTDVDVWHPEVRFFELYDENNELRGSFYLDLYAREHKRGGAWMDDCVGQMRKADGTLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFNPQQGAKILETLFEIKKQVAVVPSPTWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADAYSRFEEEGIFNRETGQSFLDNILTRGGSEEPMELFKRFRGREPQLDAMLEHYGIKG
What is the function of this protein?
May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins.  Can cleave N-acetyl-L-Ala(4).
What are the official names of this protein?
Oligopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
Protein: IQEC1_HUMAN
Sequence: MWCLHCNSERTQSLLELELDSGVEGEAPSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHTEEAPALDAARARDTEPQTALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKHGPHSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVEFQPFEPLQPSVLCS
What is the function of this protein?
Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294, PubMed:11226253).  Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294).  Accelerates GTP binding by ARFs of all three classes.  Guanine nucleotide exchange protein for ARF6, mediating internalization of beta-1 integrin (PubMed:16461286).  Involved in neuronal development (Probable).  In neurons, plays a role in the control of vesicle formation by endocytoc cargo.  Upon long term depression, interacts with GRIA2 and mediates the activation of ARF6 to internalize synaptic AMPAR receptors (By similarity).
What are the official names of this protein?
IQ motif and SEC7 domain-containing protein 1, ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, Brefeldin-resistant Arf-GEF 2 protein, BRAG2.
What is the protein family that this protein belongs to?
Belongs to the BRAG family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Postsynaptic density. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=At steady state, may be preferentially cytosolic.
Protein: Y4747_BACC1
Sequence: MKVSYHGHSVVKIETNGKVILIDPFLTGNPKTDLKAEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVKTHPMHIGGSHEFDFGKVKFTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTLYHAGDTALFSDMKLIGELNNIDVAFLPIGDNFTMGPEDAVLAAKWVQAKTVVPMHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BCE_4747.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: UNG_ECOSE
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF2M_MOUSE
Sequence: MFTKWRIFAVNHQRTFSVHLNTMCYCKIKANLKRLKTQLPLTRNYSSAPGIAGSDVKSLHSVINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGDTVTDFMAQERERGITIQSAAVTLDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGVEAQTLTVWRQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKAKPLILQLPIGEARTFQGVVDVVNKEKLLWNSNSDDGKDFERMPLSEASDRELLKETIEARNSLIEQVADLDDEFADLVLGEFSENFDLVPAEKLQAAVHRVTLAQAAVPVLCGSALKNKGVQPLLDAVTTYLPSPEEREDRFLQWYEGDLCALAFKVLHDKQRGPLVFLRIYSGTLTPQLAVHNINRNCTERMSRLLLPFADQHVEIPSLTAGNIALTVGLKQTATGDTIVSSKSSALAAARRAGRGEREHGKKREAESLLLAGVEVPEPVFFCTIEPPSVAKQPDLDHALERLQREDPSLKVKLDPDSGQTVLCGMGELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRVLGDKRHLVSAELEVRPAEEPCAVAKIEYADCVGEDLLQASREAIESAVHSACLQGPLLGSPVQDVAMTLHSLMIHPGTSTTMVTACISRCMQKALKKADKQVLEPLMSLEVTVSREYLSPVLADLAQRRGNIQEIQTRQDNRVVLGFVPLAEIMGYSTVLRTLTSGSATFALELSTYQAMSPQDQSALLNQRSGLAHVL
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Acts in collaboration with MRRF.  GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACA5_ORYSJ
Sequence: MESASSSLATSGRRRSSSGGGGGSWGSIGSAADPFDIPAKGAPVESLKKWRQAALVLNASRRFRYTLDLKREEQREEVISKIRAQAHVVRAAFRFKEAGQVHVQQKEVAAPPVDGALGFGIKEDQLTALTRDHNYSALQQYGGISGVARMLKTDTEKGISGDDSDLTARRNAFGSNTYPRKKGRSFLAFLWDACKDLTLIILMVAAAVSLALGITTEGIKEGWYDGASIAFAVLLVVVVTATSDYKQSLQFQNLNEEKQNIKLEVVRGGRRISVSIYDLVAGDVVPLKIGDQVPADGILISGHSLSVDESSMTGESKIVHKDQKSPFLMSGCKVADGYGTMLVTAVGINTEWGLLMASISEDSGEETPLQVRLNGVATFIGMVGLSVALAVLVVLLARYFTGHTYNPDGSVQYVKGKMGVGQTIRGIVGIFTVAVTIVVVAVPEGLPLAVTLTLAFSMRKMMRDKALVRRLSACETMGSATTICSDKTGTLTLNQMTVVEAYFGGKKMDPPDNVQVLSASISSLIVEGIAQNTSGSIFEPENGQDPEVTGSPTEKAILSWGLKLGMRFNDTRTKSSILHVFPFNSEKKRGGVAVHLGGSESEVHIHWKGAAEIILDSCKSWLAADGSKHSMTPEKISEFKKFIEDMAASSLRCVAFAYRTYEMVDVPSEDRRADWILPEDDLIMLGIVGIKDPCRPGVKDSVRLCAAAGIKVRMVTGDNLQTARAIALECGILSDPNVSEPVIIEGKAFRALSDLEREEAAEKISVMGRSSPNDKLLLVKALRKRGHVVAVTGDGTNDAPALHEADIGLSMGIQGTEVAKESSDIIILDDNFASVVRVVRWGRSVYANIQKFIQFQLTVNVAALIINVVAAVSSGNVPLNAVQLLWVNLIMDTLGALALATEPPTDHLMQRPPVGRREPLITNVMWRNLIIMALFQVIVLLTLNFRGTSLLQLKNDNQAHADKVKNTFIFNTFVLCQVFNEFNARKPDELNIFKGITGNHLFMAIVAITVVLQALIVEFLGKFTSTTRLTWQLWLVSIGLAFFSWPLAFVGKLIPVPERPLGDFFACCCPGSKQAADAKGDDADHSDV
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles (By similarity).  Involved in salt and drought stress tolerance (PubMed:24128296).  Involved in cold stress tolerance (PubMed:24992889).
What are the official names of this protein?
Calcium-transporting ATPase 5, plasma membrane-type, OsACA5, Ca(2+)-ATPase isoform 5, OsACA6.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHIT1_MOUSE
Sequence: MVQSLAWAGVMTLLMVQWGSAAKLVCYLTNWSQYRTEAVRFFPRDVDPNLCTHVIFAFAGMDNHQLSTVEHNDELLYQELNSLKTKNPKLKTLLAVGGWTFGTQKFTDMVATASNRQTFVKSALSFLRTQGFDGLDLDWEFPGGRGSPTVDKERFTALIQDLAKAFQEEAQSSGKERLLLTAAVPSDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLEKTTGHNSPLYKRQGESGAAAEQNVDAAVTLWLQKGTPASKLILGMPTYGRSFTLASSSDNGVGAPATGPGAPGPYTKDKGVLAYYEACSWKERHRIEDQKVPYAFQDNQWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQGPYPLIRTLRQELNLPSETPRSPEQIIPEPRPSSMPEQGPSPGLDNFCQGKADGVYPNPGDESTYYNCGGGRLFQQSCPPGLVFRASCKCCTWS
What is the function of this protein?
Degrades chitin, chitotriose and chitobiose.  May participate in the defense against nematodes and other pathogens (By similarity).
What are the official names of this protein?
Chitotriosidase-1, Chitinase-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted. Lysosome. Note=A small proportion is lysosomal.
Protein: TTCA_ECOLC
Sequence: MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATSY_SYNE7
Sequence: MPAAIVHSADPSSTSILVEVEGMKCAGCVAAVERRLQQTAGVEAVSVNLITRLAKVDYDAALIEDPTVLTTEITGLGFRAQLRQDDNPLTLPIAEIPPLQQQRLQLAIAAFLLIVSSWGHLGHWLDHPLPGTDQLWFHALLATWALLGPGRSILQAGWQGLRCGAPNMNSLVLLGTGSAYLASLVALLWPQLGWVCFFDEPVMLLGFILLGRTLEEQARFRSQAALQNLLALQPETTQLLTAPSSIAPQDLLEAPAQIWPVAQLRAGDYVQVLPGDRIPVDGCIVAGQSTLDTAMLTGEPLPQPCQVGDRVCAGTLNLSHRLVIRAEQTGSQTRLAAIVRCVAEAQQRKAPVQRFADAIAGRFVYGVCAIAALTFGFWATLGSRWWPQVLQQPLPGLLIHAPHHGMEMAHPHSHSPLLLALTLAISVLVVACPCALGLATPTAILVATGLAAEQGILVRGGDVLEQLARIKHFVFDKTGTLTQGQFELIEIQPLADVDPDRLLQWAAALEADSRHPLATALQTAAQAANLAPIAASDRQQVPGLGVSGTCDGRSLRLGNPTWVQVATAKLPTGSAAATSIWLADDQQLLACFWLQDQPRPEAAEVVQALRSRGATVQILSGDRQTTAVALAQQLGLESETVVAEVLPEDKAAAIAALQSQGDAVAMIGDGINDAPALATAAVGISLAAGSDIAQDSAGLLLSRDRLDSVLVAWNLSQMGLRTIRQNLTWALGYNVVMLPLAAGAFLPAYGLALTPAIAGACMAVSSLAVVSNSLLLRYWFRRSLNHSVSV
What is the function of this protein?
Involved in copper transport.
What are the official names of this protein?
Probable copper-transporting ATPase SynA.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNC_MYCGA
Sequence: MENLEKNTKKKIKKPNNFKKNNKDKTEELKDKPTPRMFKMTPKSSKFLHQLGVTGRKHTEKPVPLNDPDYEKKIREIQAKEAKKIRSDEVVNNNSKKQNNNKQAKKKANKNKKQKGNNNNFQNNKKPENWKQKPAANNQVKAIPNSEKSTAKTAINLIIKRTFETLKQNNLIAPNLKQNPNKKDKPQQPNVAAKNNNQKEVKKPYNNFVNNQKNHNKNNAGNKGDNKQPTKPLNQSKLSKSTIVELPFTPNFTSNQPKPTQKEDSKKVKAKKAENSQPQESNKQVKKLEVKTNQQKQDQTKKKQPKENKNQQIKAVNLNNNQQKTNNNNQKNSVDKSENDNNKKKSEANQKQENLNPNNNNKKKEDSKNESNNIPLINKNISDQQIVKISNYIKDNYPVIYADLKEKNRLGFNSNLDDDKLIVYANYEAKDLELLLKKFKVVTNNIGLYEEALTHNSYANEMHLKYNYQRLEFLGDAIINKIVAEYLFNHSDSSEGEMTKDRIKIIQSNTLIKAATQLELINYIRVGEGLKIAPLSPKILEDIFEAFIGAMYLDQGEYAVRKILNDTIIGYYQKGQLTENTDYKSIFQEIIHSTGLNMKIHYERTYDRQKNLHTVSLYAGGIMYGEGKDSSTHKAEIKAAKEAISKFRGLLKLEK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTD_SALTI
Sequence: MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_CHLFF
Sequence: MKKVPIKVCVSNKQKDVPIRVQSAKKLVLCCLQYWKITTDQVYIYFLDDKALAQIHDEVFSDPSLTDTITLPIDSPGISSHPHVLGEAFISPKAAIRFLKDRSQDSDLLYEEISRYVVHSLLHMLGYDDQTPEERKKMRVKENQALCMLREKHALLSD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.