PharMolix/UniProtQA huggingface dataset:
Protein: 2SS_CUCMA
Sequence: MARLTSIIALFAVALLVADAYAYRTTITTVEVEENRQGREERCRQMSAREELRSCEQYLRQQSRDVLQMRGIENPWRREGGSFDECCRELKNVDEECRCDMLEEIAREEQRQARGQEGRQMLQKARNLPSMCGIRPQRCDF
What is the function of this protein?
This is a 2S seed storage protein.
What are the official names of this protein?
2S seed storage albumin protein, 2S albumin.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Protein: CLZ17_COCLU
Sequence: MATVNGAVGKPQHISKMIESTKMNGNQAQDAAGRADTPVSSDTPDYLHVFDSRTCNIHHIPVSDGFVRGSDLSTIAAPVKGNSGRMQKLAVLDPGFQHTACKESGITFIDGEKGELRYRGVRIEDLFHDHDFDSTLHLLLWGRLPTNDEKIAFERRIFEAATPPQEVCDVIRKLPKNTDFISMFLTGLSTYMGADEEMTRSRHQAVMTYHKNMKATDDAIIRCFAYVSATLATVYCHVKGVELHPPKEGLTLVENFLHMIGMEDPDKKVSRTIDRLSINMADHELSCSTAAFLHVASSLTDPMTCLLTAISAASGPLHGGALEVCYQGLELIGSVENVPAYIAAVKAKKFRLFGYGHRVYKTQDPRAALTKELMEEHREAIAANPLLQIAVEIDRQANTDPYFVERKLKLNADFYGCFVYIAL
What is the function of this protein?
Citrate synthase-like protein; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:28605916).  SQS1 is composed of a 2,8-dioxobicyclic[3. 2. 1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms (PubMed:28605916).  These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase clz14, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product (PubMed:28605916).  The phenylalanine ammonia lyase (PAL) clz10 and the acyl-CoA ligase clz12 are involved in transforming phenylalanine into benzoyl-CoA (PubMed:28605916).  The citrate synthase-like protein clz17 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit (PubMed:28605916).  The potential hydrolytic enzymes, clz11 and clz13, are in close proximity to pks2 and may participate in product release (PubMed:28605916).  On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase clz2 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase clz6 (By similarity).  The biosynthesis of the tetraketide must involve 3 rounds of chain extension (By similarity).  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (By similarity).  The enoyl reductase and C-MeT of clz2 are not active in the final round of extension (By similarity).  The acetyltransferase clz6 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (By similarity).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases clz3, clz15 and clz16 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) clz20, suggesting a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Citrate synthase-like protein clz17, Squalestatin S1 biosynthesis cluster protein clz17, Zaragozic acid A biosynthesis cluster protein 17.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: ARGC_THEPX
Sequence: MVKVGIFGATGYTGVELIRILSKHEKVEIKYLSSQSYNTIAISNVYSSLLGFCDKVLEEVDFERAMSECDVIFTALPSGHAAKIAREAVKKGIKVIDLGADFRFDDYSIYKEWYSGEYDGYDGIKRVYGLPEIYRDDIKEAQVVGNPGCYPTSVILGLMPLLKNGIIEGKIIVDSKSGVSGAGRSPSQNNMYAECNENIKAYNVAKHRHIPEMEQELSKIFGETVSVVFTPHLAPMTRGILSTMYCKLKKDIDVDTVYDIYADFYKKEYFIKVLEPGHYPATKSVYGSNFCHIGFEVDKRTNTLIVMSAIDNLVKGASGQAVQNMNIMFGIDENTGLDIVPIYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT_EISFE
Sequence: DTQCCGKSTCAREGSTCCCTNCRCLKSECLPGCKKLCCADAEKGKCGNAGCKCGAACKCSAGSCAAGCKKGCCGD
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.  Binds 4 cadmium ions per molecule.
What are the official names of this protein?
Cadmium-metallothionein, MT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEEP_CLOAB
Sequence: MIIKDIVIGHLSVPLKKPFKTAVRSVNSVNDVVVKIITDTGNVGFGSAASTGLVTGDITESIEGAINNYIKRSIVGMDIEDFEAILIKLDNCIVGNTSAKAAVDIALYDLYGQRYGAPLYKLLGGFRNKLETDITISVNSPEEMSRDSVDAVKLGYKTLKIKVGKNPKLDIKRMREIRKAIGYEVNLRIDANQGWQPKEAIRALNEIENEGLKIELVEQPVKAWNLEGLKMVTDNVNIPVMADESVFSPKDAARVMEMRACDLINIKLMKTGGIHNALKICALAEVYGMECMLGCMLEGKVSVTAAVHLAAAKRIITKIDLDGPVLCSRDDVVGGAMYDNSNIVLVDEPGLGIEGINN
What is the function of this protein?
Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component.  Is also able to catalyze the epimerization of L-Ala-D-Asp.
What are the official names of this protein?
L-Ala-D/L-Glu epimerase, AE epimerase, AEE.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: RL36_CHLSY
Sequence: MKVRASVKPRCEYCKVIKRKGVIRVICSRTPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RS3_ESCF3
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HUTH_AGRFC
Sequence: MTMKTITLHPGAVTLADLAAIYWENGTAKLDRSFDAGIEKAAARIAEIAAGNAPVYGINTGFGKLASIKIDAADVATLQRNLILSHCCGVGVPLPENVVRLIMALKLVSLGRGASGVRLELVRLIEAMLEKGVIPVIPEKGSVGASGDLAPLAHMAAVMMGEGEAFYEGAPLPAGEALAKAGLTPVVLAAKEGLALINGTQTSTALALAGLFRAHRAAQAALITGALSTDAAMGSSAPFHPDIHSLRGHKGQIDAGAALRNLLEGSEIRVSHIEGDERVQDPYCIRCQPQVDGACLDLLRQVARTLEIEANAVTDNPLVLSDNSVVSGGNFHAEPVAFAADQTALAICEIGAIAQRRVALLVDPALSYGLPAFLSKKPGLNSGLMIAEVTSAALMSENKQMAHPASVDSTPTSANQEDHVSMACHGARRLLPMTDNLFAILGIEALSAVQGVELRGPLKTSPELQKVIAVLRVVVPSLEEDRYMAPDLKAAAELIASGALVSTISGGILPKLEA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAB_AERS4
Sequence: MSLDMQEWRAETTAIVNELLADGSNPDLEYDIEHHFACQDFDQLEKAAVDLFKAGFEVTDAEEMELDDGAPIFCFDATIERKLDIETIVADIEKMLPILKKYGVDYDGWGTYFQE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity B.
What is the protein family that this protein belongs to?
Belongs to the RraB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_PISOC
Sequence: MPQLELISWFFNFLLAWFFLFIVVTILLKINFPSTNYITVTHPQKLNIFNNWLWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SYS_CHLTR
Sequence: MLDIRLIRKEPKECESRLQKKDPAISLERLLDLDKTVRQLKADSEALLAKRKVLSGQIHKAKVANENADALIQEVNTIADQLVAFETTLQEQEALLEDLMARLPNYPDEDVPVSPDKTGNQVIKGHGEVPTFPFPPKHHMQLNEALQILDFKLPAKTTGSGWPAYCNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGDQSLFLIPTAEVVLNGFHSQEILNEQDLPLCYAAFTPCFRREAGAGGAHERGLVRVHQFHKVEMFAFTTPEQEEVVYQKMLHVVEEILSELQLPYQLSLLSTGDMSFTAKKTIDAEVWLPGQKAFYEVSSISKCGDFQARRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQQADGSVVIPSVLRPYMNNQEILLPKTVR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM82_HUMAN
Sequence: MFSLPSLPSWLPGLPSLEWGSSLLDSLLQGLIGALGVLVLNSLLKVYFFVGCANDPQRRPEKERLRAQWASLETVHLAGLALFLTVVGSRVAALVVLEFSLRAVSTLLSLGKGSQGAAERLQLYLLCQYSLGCGLTCGLSFLQEGAPHRTLNLLLSLGLATLLGLGARRLHRHVCRLYELHSSQRYCGVCLGLLAHAHGLPQLLGRALAIAFAVGDLAAVALINQDFLTTSEAMRFWTPLTICYTLLVIYMQEEQRQHPGLQSQVQTVLVRMGGLFVLLLTVGRWLDLLGILVSLLGELWCLVGVRTLLDLCQIQDFPSQRPPVSTPSQPLPSAPQSQSSAPS
What are the official names of this protein?
Transmembrane protein 82.
What is the protein family that this protein belongs to?
Belongs to the TMEM82 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DIUX_CAMFO
Sequence: MTVLCTLMAFVMVVAISSLTVDAIPHSHESYWDQQDDIDRDEFLELLSRLSRTVMNRPEMENSKRGLDLGLSRGFSGSQAAKHLMGLAAANYAGGPGRRRRSEQA
What is the function of this protein?
Regulation of fluid secretion.  Stimulates Malpighian tubules fluid secretion.
What are the official names of this protein?
Diuretic hormone class 2, DH(31), Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the diuretic hormone class 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYC_ASPNG
Sequence: GKDASFAPGDSAKGAKLFQTRCAQCHTVEAGGPHKVGPNLHGLFGRKTGQSEGYAYTDANKQAGVTWDENTLFSYLENPKKFIPGTKMAFGGLKKGKERNDLITYLKESTA
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: CYCR_ROSDO
Sequence: MFPKWFDKWNADNPTNIFGPAILIGVLGVAVFGAAAIVSIGNPAQTASMQTGPRGTGMHVAEFNVTRFAPDPTIEEYYTEAPYIPEGGEELAKDIYENVQVLGDLTDDNFNRVMTAMTQWIAPEEGCVYCHGEGDLETYGEDNLYTKVVARRMIQMTQNINENWDGHVNANAEVGVNCYTCHRGEHVPSEIWFNITPVTEATAGWASVQNRATPLSQSTSLPSNALEIYLTEYEAVNVHDLESRVAGVPNDVEVASIQKTEMTFSLMNYFSNSLGVNCVFCHNSRAFYDPGQHTPQWATALLGRQMVIEMNQEYLIPLEDEYPEDRLGPVYADAPKAACKTCHKGYQKPMQGLNVIADWPELATTEAPVYE
What is the function of this protein?
The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.
What are the official names of this protein?
Photosynthetic reaction center cytochrome c subunit.
What are the subcellular locations of this protein?
Cellular chromatophore membrane.
Protein: BR2_PELLE
Sequence: GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC
What is the function of this protein?
Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
What are the official names of this protein?
Brevinin-2E.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: PRE1_ARATH
Sequence: MSNRRSRQSSSAPRISDNQMIDLVSKLRQILPEIGQRRRSDKASASKVLQETCNYIRNLNREVDNLSERLSQLLESVDEDSPEAAVIRSLLM
What is the function of this protein?
Atypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development.  Binds IBH1, forming a pair of antagonistic bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation.  Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance.  May have a regulatory role in various aspects of gibberellin-dependent growth and development.
What are the official names of this protein?
Transcription factor PRE1, Basic helix-loop-helix protein 136, AtbHLH136, bHLH 136, Protein BANQUO 1, Protein PACLOBUTRAZOL RESISTANCE 1, bHLH transcription factor bHLH136.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_ECO55
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGTDALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_ACTSZ
Sequence: MSKLSVVILAAGKGTRMYSDLPKVLHKVAGKPMVKHVIDTAKQLSAEQIHLIYGHGADLLKERLADEPVNWVFQAEQLGTGHAMQQAAPFFKDDENIVMLYGDAPLITKETLERLVAAKPENGIALLTVELENPTGYGRIIRENGSVVAIVEQKDATPEQLKITEVNTGVMVSDGASFKKWLARLDNDNAQGEYYMTDVIGLANQDGFKVAAVTADDMMEVEGANNRLQLAALERYFQRKQATALLLAGVSLADPERFDLRGELEHGKDVEIDVNVIIEGKVKLGNGVKIGAGCVLKNAIIGDNTEIKPYSVLEDSSVGEQAAIGPFSRLRPGAELAAETHVGNFVEIKKAVVGKGTKVNHLTYVGDAEIGSGCNIGAGVITCNYDGANKFKTLIGDNVFVGSDVQLVAPVKVNNGATIGAGSTITKDVAAGELVTTRVPQRHTADWERPSKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILEU_XENTR
Sequence: MENLSSACTHFSFDLFRKINENNATGNVFFSPISISTALAMVLLGARGNTAQQISRILHFDAVKDLHSNFQTLNAEINKKNVSSYALNLANRLFGEKSFKFLPDFLSSVKKQYNADLGTVDFISAAEDARKEINTWVSEQTKGKIPEVLSAGAVNSFTKLVLVNAIYFKGDWAKKFKAEHTKDMPFQLNKKEQKTVKMMYQMEKLPFNYIPEINCRVLELPYVDYELSMVIVLPDNINDDTTGLQQLEKELSLEKINEWTENMMPIDVHVHLPKFKLEDSYKLKSQLAGMGMADLFEAGSADLSGMSGSNDLYLSEVIHKSFVEVNEEGTEAAAASAGIAMMCLMREEEFNANHPFLFFIRHNATKSILFFGRYSSP
What is the function of this protein?
Regulates the activity of the neutrophil proteases.
What are the official names of this protein?
Leukocyte elastase inhibitor, Serpin B1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_WOLSU
Sequence: MNKIIIGTRGSVLALWQAEYVKAELERAHEGLSVELKIVKTKGDKILDVPLAKVGGKGLFTKELEEMMLQGEIDLAVHSLKDVPVELIEGLTLSAITEREDVRDCFLSDKYASLETLPLGAKVGTTSLRRSMQIKSMRSDLDTESLRGNVQTRIKRLKEGDFDAIILATAGVNRLDLWKEVNYVIPIDTEMMIPAMGQAALGIECKEGSEAFRLTQILEDKKARIETTAEREFVRVLEGGCQVPIGANAYLEGETLHLKVAVGLPDGSEILMDRLSAPKGEAVRLGRELAARLIAKGARELLRRAEEMAFQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PRIB_BORBR
Sequence: MNTLELSARVLECGAMRHTPAGLPALELLLVHESEVVEAGHPRRVELTISAVALGDLALLLADTPLGTEMQVQGFLAPARKDSVKVKLHLQQARRIAGSMGRDPLVG
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: CLPX_LACGA
Sequence: MANEITEQEEVKCSFCGKPQSQVKKIVAGNGVYICNECIDLSKKIIDDELKADSIKETKDLPKPMEIKKQLDEYVIGQDRAKKVLSVAVYNHYKRISQMDIDSSGTELQKSNIALIGPTGSGKTYLAQTLAKILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYDLERAQRGIIYIDEIDKISKKAENVSITRDVSGEGVQQSLLKILEGTIASVPPQGGRKHPQQQMIKIDTTNILFIVGGAFDGIENIVKNRLGKKTIGFGAENGLNQVDADDWQKNLTTGDLVKFGLIPEFIGRIPIITTLDKLSTKDLIRILTEPKNALVKQYKKLLSLDNVDLEFTEGALKAIADMAISRHMGARGLRSIVENSLMDVMYRTPSEDNIEKVEITKDVITKHAQPKITYKENESQEASEAAK
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SODM_STAEP
Sequence: MAFELPKLPYAFDALEPHIDKETMEIHHDKHHNTYVTKLNAVVEGTDLEAKSIEEIVANLDSVPSDIQTAVRNNGGGHLNHSLFWELLTPNSEEKGEVVEKIKEQWGSLDEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYISAFWNVVNWEKVDELYNAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: INT9_BOVIN
Sequence: MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSNLPGWSLKDGNAFLDKELKECSGHVFVDSVPEFCLPETELIDLSTVDVILISNYHCMMALPYITEHTGFTGTVYATEPTVQIGRLLMEELVNFIERVPKAQSASLWKNKDIQRLLPSPLKDAVEVSTWRRCYTMQEVNSALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDSMVGEFCSNLALTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSSIPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFRQPCVVFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLEALAPYQPLAMKCIYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPTPAQSHRMDLMVDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHVLQPPPRPTQPTGGKKRKRASDDIPDCKVLKPLLSGSIPVDQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDDDEVLRVRLRDLVLKFLQKF
What is the function of this protein?
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 9, Int9.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y654_MYCBO
Sequence: MALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGYKGLLAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAGDKLYCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDGEGFSDGAA
What are the official names of this protein?
UPF0336 protein Mb0654.
What is the protein family that this protein belongs to?
Belongs to the UPF0336 family.
Protein: MFP1_TOBAC
Sequence: MGSSCFPQSPLSHSLFSSSSLSSSQFTPLLFSPRNAQKCKKKMPAMACIHSENQKESEFCSRRTILFVGFSVLPLLSLRANAFEGLSVDSQVKAQPQKEETEQTIQGNAENPFFSLLNGLGVFGSGVLGSLYALARNEKAVSDATIESMKNKLKEKEATFVSMEKKFQSELLNERDIRNNQLKRAGEERQALVNQLNSAKSTVTNLGQELQKEKRIAEELIVQIEGLQNNLMQMKEDKKKLQEELKEKLDLIQVLQEKITLLTTEIKDKEASLQSTTSKLAEKESEVDKLSSMYQESQDQLMNLTSEIKELKVEVQKRERELELKRESEDNLNVRLNSLLVERDESKKELDAIQKEYSEFKSISEKKVASDAKLLGEQEKRLHQLEEQLGTASDEVRKNNVLIADLTQEKENLRRMLDAELENISKLKLEVQVTQETLEKSRSDASDIAQQLQQSRHLCSKLEAEVSKLQMELEETRTSLRRNIDETKRGAELLAAELTTTRELLKKTNEEMHTMSHELAAVTENCDNLQTELVDVYKKAERAADELKQEKNIVVTLEKELTFLEAQITREKESRKNLEEELERATESLDEMNRNAFALAKELELANSHISSLEDEREVLQKSVSEQKQISQESRENLEDAHSLVMKLGKERESLEKRAKKLEDEMASAKGEILRLRTQVNSVKAPVNNEEKVEAGEKAAVTVKRTRRRKTATQPASQQESS
What is the function of this protein?
Binds DNA.  Interacts with chromatin via matrix attachment regions (MARs).  Likely to participate in nuclear architecture by connecting chromatin with the nuclear matrix and potentially with the nuclear envelope (By similarity).
What are the official names of this protein?
MAR-binding filament-like protein 1-1.
What are the subcellular locations of this protein?
Nucleus matrix.
Protein: AROK_NEIMB
Sequence: MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRETVQTLLKRLSR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Putative shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_POLSJ
Sequence: MPRRREVPKREILPDPKFGDVDLAKFMNVIMQGGKKAVAERIIYGALDFIEKKNPGKDPLEAFHMAIGNIKPMVEVKSRRVGGANYQVPVEVRPVRRMALAMRWLKEAAKKRGEKSMSLRLANELMEATEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.