PharMolix/UniProtQA huggingface dataset:
Protein: ZP3_BOVIN
Sequence: MGPCSRLFVCFLLWGSTELCSPQPFWDDETERFRPSKPPAVMVECQEAQLVVTVDKDLFGTGKLIRPADLTLGPDNCEPLASADTDGVVRFAVGLHECGNILQVTDNALVYSTFLLHNPRPAGNLSILRTNRAEVPIECHYPRQGNVSSWAIQPTWVPFRTTVFSEEKLVFSLRLMEENWSAEKMTPTFQLGDRAHLQAQVHTGSHVPLRLFVDHCVASLTPDWSTSPYHTIVDFHGCLVDGLTDASSAFKAPRPRPEILQFTVDVFRFANDSRNMIYITCHLKVTPVDRVPDQLNKACSFSKSSNRWSPVEGPTDICRCCSKGRCGISGRSMRLSHREGRPVPRSRRHVTEEADVTVGPLIFLRKMNDRGVEGPTSSPPLVMLGLGLATVMTLTLAAIVLGLTGRLRAASHPVCPVSASQ
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP3 is essential for sperm binding and zona matrix formation.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3, Sperm receptor, Zona pellucida glycoprotein 3, Zp-3, Zona pellucida glycoprotein 3B, Zp-3B, Zona pellucida protein C.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPC subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 3]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: RLMH_MYCCT
Sequence: MKIKIICFGKLDKAFYVDAFNDYFKRLKKYVDLEIIELKEEINGELNKIKDENSNLLLKKLENYKDFEKIILDVNSKLISTENLVEIIKTNLNYKTAKILFVIGPSDGYSKSFLNSFTNKFSLAKITLPHQLCRIVLIEQIYRVFKIINNEKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPA_STAAC
Sequence: MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CapA.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KHSE_CORDI
Sequence: MAIELPVGKKVTVTVPASSANLGPGFDTLGLALSLYDTVEVEVTDHGLEVEVFGEGQGELPLDGSHLVVKAIRAGLKAADVQVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLAGFPLDDARVVQLSSAFEGHPDNAAASVLGNAVVSWTEIPVDGRTEPQFKAVTINVDSRIKATALVPDFHASTEAVRRVLPSDVTHLDARFNVSRCAVMTVALQHHPELLWEGTRDRLHQPYRADVLPVTAEWVNRLRNRGYAAYLSGAGPTIMVLHTEPVDEAVLNDAREAGLRVLSLDVADAVSVKVDA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_RHILW
Sequence: MPDSRPDTELSNPQSAKAPLDPHLKALENESIHIFREVAAEFERPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHVNTGWKFREMIAFRDETAKKYDLDLIEHINPRGAAENITPFTHGSAAFTDIMKTEGLRQALDAGQFDAAFGGARRDEEASRAKERIYSFRTPDHRWDPRNQRPELWNVYNGMIRKGESVRAFPLSNWTEVDIWRYIQAEDIPLVPLYYAKKRPFVERDGMMILAEDPRLELLPGEVRQEGMIRFRTLGDFPLTGAIRSQATTLEEVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RSMG_ALIB4
Sequence: MLQKLLEANNLKFEDKFYEDCEVFVKLLQQWGTIHNLSGRLTRDDIYENILDSLYPLTFIEKYESFADIGTGAGYPGLILAIALRDTKAYLIEPRIKRVSFLNFVKATLKLDNLVVLCNRVEEVKDLQVDLITSRAVTNTSLLLDITKNIKKPNSSYLFYKGSMLESELENAKVNNYKIVNKKDRNYLYIKGLI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_LEPCP
Sequence: MATITAKMVGDLRAKTDAPMMECKKALTEADGNMEKAEELLRVKLGNKASKAASRVTAEGVVASAVSGSTGALIEVNCETDFVSKNDSFLAFVQACVNLVVEHNPADVAALSALPLAMEDFGPTVEDVRKGLIGKIGENLAIRRFKRYGDGGSLAHYLHGVRIGVMVEYSGDAVAAKDVAMHIAAMKPVSLTSADVSADLIEKERAVAAGKAAEDAKAAEAAGKPAQSAEIVAKRIEGSIQKFLKEVSLFNQTFVKNDKQTVEQMLKAAGTTVKGFTMYVVGEGIEKKQDDFAAEVAAQVAAAKGQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACC1_PONAB
Sequence: MLITERKYFWSGRIAQSRSEANLVDMEAGKLSKSCNITECQDPDLLHNWPDAFTLHGNNASKVTNPFWNQLSASNPFLDDITQLRNNRKRNNISILKEDPLLFFREIENGNSFDSSGDELDVHQLLRQSSSRKSGRSKSVSELLDILDDTAHAHQSIHNSDQILLHDLEWLKNDREAYKMAWLSQRQLARSCLDLNTISQSPGWAQTQLAEVTKACKVNHQGGSVQLPESDITVHVPQGHVAVGEFQEVSLRAFLDPPHMLNHDLSCTVSPLLEIMLGNLNTMEALLLEMKIGAEVGKDPFSQVMTEMVCLHSLGKEGPFKILSNCYIYKDTIQVKLIDLSQVMYLVVAAQAKALQSPAATIWDYIHKTTSIGIYGPKYIHPSFTVVLTVCGHNYMPGQLTISDIKKCGKNISPVVFQLWGKQSFLLDKPQDLSISIFSCDPDFEVKTEGERKEIKQKQLEAGEVVHQQFLFSLVEHREMHLFDFCVQVELPNGEPVAQFCITTPDPTPNLKRLSNLPGYLQKKEEIKSAPLSPKILVKYPTFQDKTLNFTNYGVTLKAVLRQSKIDYFLEYFKGDTIALLGEGKVKVIGQSKVKEWYVGVLRGKIGLVHCKNVKVISKEQVMFMSDSVFTTRNLLEQIVLPLKKLTYIYSVVLTLVSEKVYDWKVLADVLGYSHLSVEDFDQIHADKESEKVSYVIKKLKEDCHTKRNTRKFLYELIVALLKMDCQALVARLIREAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGNTGDVAVEMMWKPAYDFLYTWSAHYGNNYRDVLQDLQSALDRMKNPVTKHWRELTGVLILVNSLEVLRVTAFSTSEEVWK
What is the function of this protein?
Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling.
What are the official names of this protein?
Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NHLC1_HUMAN
Sequence: MAAEASESGPALHELMREAEISLLECKVCFEKFGHRQQRRPRNLSCGHVVCLACVAALAHPRTLALECPFCRRACRGCDTSDCLPVLHLIELLGSALRQSPAAHRAAPSAPGALTCHHTFGGWGTLVNPTGLALCPKTGRVVVVHDGRRRVKIFDSGGGCAHQFGEKGDAAQDIRYPVDVTITNDCHVVVTDAGDRSIKVFDFFGQIKLVIGGQFSLPWGVETTPQNGIVVTDAEAGSLHLLDVDFAEGVLRRTERLQAHLCNPRGVAVSWLTGAIAVLEHPLALGTGVCSTRVKVFSSSMQLVGQVDTFGLSLYFPSKITASAVTFDHQGNVIVADTSGPAILCLGKPEEFPVPKPMVTHGLSHPVALTFTKENSLLVLDTASHSIKVYKVDWG
What is the function of this protein?
E3 ubiquitin-protein ligase.  Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways.  In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS).  Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation.  Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation.  Also promotes proteasome-independent protein degradation through the macroautophagy pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase NHLRC1, Malin, NHL repeat-containing protein 1, RING-type E3 ubiquitin transferase NHLRC1.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Nucleus. Note=Localizes at the endoplasmic reticulum and, to a lesser extent, in the nucleus.
Protein: SYL_DESAL
Sequence: MDERYDPKKIEGKWQAHWDAAGLFKVKEDPSKEKYFLMEMFPYPSGKIHMGHVRNYSIGDVVARFKRMQGFNVLHPMGWDAFGMPAENAAIKNNTHPAKWTYENIAAMGAQLKAMGFSYDWDREIATCKPDYYRWEQWLFVQMFKKGMVYRKEASVNWCHTCQTVLANEQVEQNMCWRCGDEVEQKKLKQWFFRITDYADDLLEHCDKLPGWPEKVVTMQKNWIGKSHGAEILFSVKDSDVKIKVFTTRPDTLCGATFMCLAPEHPLVEDLSKGTAQEAVVQEFVARMAKQDKAKRTADDKEKEGVPIGAQCINPLTGKTMEIYTANFALMEYGTGAVMSVPTHDQRDFEFATKYGLEKIVVIQPEGEALSPETMTEAYTDPGVLVNSGQFDGMKNTDAMEAIAQYLDENDMGKKTVQYRIRDWGISRQRYWGAPIPMIHCPDCGITPVPEDQLPVILPEDANLLEGGKSPLPELDSFVKTTCPQCGNENARRETDTMDTFVESSWYPERYCSPKCDDGMFDVDAVKYWMPVDQYIGGVEHAVMHLLYSRYFTRVLNDFGLVDFKEPFTRLLTQGMVCKETLKCPEHGWLFPHEVEGSGDERTCTKCGKIVEAGRVEKMSKSKLNVVDPEELLAKYGADTIRLFCLFAAPPERDLDWSEEGVEGSYRFLQRVWRMFAAHMDEVKDAQPFEGSPDDLDGYLKDLYKKTHQTIKKVTEDIDGRFHFNTAISAVMELVNMVYGLDDNLQGEKRAGVLRAAVEAVILLISPMTPHFTEELWSLFGKTQCVLETPWPAWREDALTADEVVVVLQVNGKLRSKLNVPLDTDDEKIKEMALADEKVQKFMGGKPIRKVIVVKNKLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_RALPJ
Sequence: MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRHKIIDVIKGLPNDPRQQRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFILGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIETLDDLRISDAIKVGFAQCFALIPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFAVGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APN1_YEAST
Sequence: MPSTPSFVRSAVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQKKRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE
What is the function of this protein?
DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA.  APN1 accounts for > 97% of both apurinic/apyrimidinic (AP) endonuclease and DNA 3'-repair diesterase activities.
What are the official names of this protein?
Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCA_COXBU
Sequence: MLVFYGFLSSRSISHLKVYLVGGAVRDQLLGLPVKEKDWVVVGATPEEMTARGFKPVGKEFPVFLHPETHEEYALARTERKVAKGYKGFTFYAAPDVSLEEDLKRRDLTINAIAETPEGQLIDPYGGQEDLKNKVLRHVSVAFQEDPVRVLRLARLATKFPDFSIHPDTLELMKKMVCAGEIDALVPERIWQELNRALGNEKPTRFFTVLNQCGALAILFPEIKMEGKGMAALQSVTDKTPSPLIRFATLQSDLPPEIIQKLAGRYRVPNEYADLAILVARFGSDYVNLNRMDETSLLNFLLKTDALRRQERFDQFIFTCDLISSTTSSQPKKIKEIIKAVKSVDIKPLQEKQLKGEAFAKALEKLRLEAIRTLIS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: CBIM_STRCO
Sequence: MHIAEGFLPPAHAIAWGVASAPFVVHGVRSLTREVREHPESTLLLGASGAFTFVLSALKLPSVTGSCSHPTGTGLGAILFRPPIMAVLGTITLLFQALLLAHGGLTTLGANVFSMAIVGPWAGYGVYRLLRRWDVPLMVTVFFGAFVADLSTYCVTSVQLALAFPDPSSGFLGALGKFGSIFAVTQIPLAVSEGLLTVIVMRLLVQSSKGELTRLGVLLTRTGERKQEAVAR
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPS10_AJECG
Sequence: MILRRLLLAGSLLLATAFTSAKKADGPKISVTKFKDEPVNLFYFDDSDTVMFQDGKNGDVYVSRDAGANWDIVDVSGMRGKAWSLLPHPTDRTKAYIMSKGGTHWVTEDQAKSWREFTVDAELSRYEYPLVFHGKDSNRVMLLGHKCNGLDCKERTYYTTDGFKTVHLLMENGRHCAWAVSTPTFGEGLDLPKEVNDRIFCVVSGLHSSWAEANRLLYSDRFFKDEQGTEVPLDNGRAVSGVIRTASVQKYILAATKSARTNELALFVTDDASTWHRTEFDGHRVEEDAYTILESTSYSLQVDVVSTYSSTIGTLFTSNSNGTYFTRNIEHTNRNMYGFVDFEKISSIQGIILVNTVKNWEDVEKSNGVQKKVISKISFDDGRTFQPLKVGKHDLHLHSVTDATNSGRVFSSPAPGLVMGVGNTGGHLKDYLDGDLFVSDDAGINWRKALDDAHKYEFGDQGSVIVAVFDEGRTDKISYSLDHGKNWHKASLPDGVQIRAKVLTTAPGSTTLKFLLLGSAKADIGMEYYIISIDFAEMEERTCEEKDFENWPARLNEKNEPDCLMGHKQFYRRRKAQADCFIKKKFEEPAPEFERCKCTEEDFECDFNFVRGEDGKSCIPSRSLIAPEGVCKNPDDKFTGSSGFRLIPGNVCIREGGVDLDKQTERVCSETFKNPPAGQIVVEKSFFTADYYKDYFYLERKESSKGEDETVIMITSEQQIFLSRDHGKKWKQILEEEKITRIEPHRFFDDVAYFLTNNGDGWYTLDRGDTFRKFKAPLPPNQDKLPVLSFHPDRRDWLIWTGADECNGNGGNCHSVAYYTTNLGGEWHFLMRYVRRCEFISRDARGSSDKLVFCEQFENENPSNKHLQLLSTEDWFAEKRLHYSNILDFATMQEFIIVAIRGENSQDSLRIGVSIDGKTFADAELPANVQIPIQRAYTVLESRTHAAFLHVTINNIEDHEYGSIIKSNSNGTSYVLSLSAVNRNSRGYADFEKMQGLEGVAMANVVGNVADVENGAAKKFRTMITHNDGAEWTLMRPPDKDSEGRSYACSTKGGKPTDACALHLHSYTERADPRDTYSSPSAVGIMIGTGNVGDYLSLKSKADTFITRDAGITWEEVKKGKYQWEFGDSGSIIVLVPESTPTKTLLYSLDEGRSWKDFEFSEVEMQIQDISTVPSDTSRNFLLWGKEVGQGKKPGLATVNIDFSGLKERSKQCVLDEKKPEADDYYLWEPKHPLQPNGCLFGHRAKYHRKRPDKDCYNGRELQHLDSIGDICECTRSDYECDYNYEPQSDGSCARVAGLEPLDPKLVCTENPKAVEWYEPTGYRRIPLTKCQGGKQLNHIVAHPCPNKEEEFFKKHPRLRGIGLFFVILIPICLAATAGYYVYNHWDGKFGRIRLGETGSGGLFDRDSLLVSIPVSMVAGVVAVITALPLLVSSLWRSVSGYVRVPGGASSRRPYSSRDSFAARRSDYVGVVEDEDELLGTDDFDDDEEGDERNGQV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: PBPB_BUCAI
Sequence: MFFNFKKYFLIKVFFFVLILTLCYGLYLYVKINRFINGKVWNFPTSIYGRIVNLEPGNSYSQKEVLHLLKSTMYRKVDLVMLPGEYSIKNNTIEFIRRAFDFPDIREDEFHARLYFNKDTLVKIKNIDNNHDFSFFRLEPKLIAMLKSPEAKKRMFIPRNQYPEMLVKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMAGRTIQGGSTLTQQLIKNLFLTNTRSILRKINEIYMALILDRFYTKDRILELYLNEVYLGQDGDEQIRGFPLASIYYFGRPINELNLEQYALLVGMVKGASLYSPWTNPNLALKRRNLVLFLLYKQKYITRKIYKDLCKRSLNVQPKGNIISSHPSFIQLVCEEFHKKIYNPIKNFPGTKIFTTLDYTSQNAVEQAVKIEIPILKRKKRLKDLEVAMIVIDRFTGEVQALIGSSKPEFNGYNRALKTRRSIGSLSKPITYLTALSQPEKYHLNTWISNYPLSIKLDSGQYWTPKNNNFSFSKKVLLLDALIHSINIPTVNLSINIGLKKLVDSWLLLGISKKYITPLPSISLGAINLTPFEIAQVFQIIGSGGYKSSLSSVRSIISDDGKVLYQNLPQSIHIESSEASYLTLYGMQQVVKSGTAKSLGTIFKEFSLAGKTGTTNNLVDNWFVGIDGKQIVITWIGRDNNHTTRLYSSSGAMQIYKRYLQYQRPVPLVLKAPNNINMFYINNLGELFCKKNNQHNRMLPIWSIKNKKICNDKLSERFSIKKKKNFLFWLKNLF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity).
What are the official names of this protein?
Penicillin-binding protein 1B, PBP-1b, PBP1b, Murein polymerase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: EFP_CUPPJ
Sequence: MKIAQELRVGNVFMMNGAPMVVQKAEYNKSGRNAAVVKMKYKNLLTEAPGESVFKADDKFEVVVLERRECTYSYFADPMYVFMDADYNQFEVEQDSMGDALNYLEDGMAVEVVFYNEKAISVEMPTTLVREIVYTEPAVKGDTSSGKVLKGAKINTGFELQVPLFCNIGDKIEIDTRTGEYRSRAN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_PSEE4
Sequence: MSAVNTPAGFSDFKVADISLADWGRKEVIIAESEMPALMGLRRKYQAEQPLKGAKIIGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEQEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPAMLEKIHGVTEETTTGVHRLLDMLAKGELKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSAQSLRQEGMIVKVTEVDPICAMQACMDGFEVVSPFKDGINTGTEAGINKDLLGRIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKHWAWEEVKPQVHKIHRTGAGTFDPQNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFEQKFAELPAAKKAERLTVEVLPKKLDEEVALEMVRGFGGVVTQLTPQQAEYIGVTVEGPFKPDAYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBL7_ARATH
Sequence: MDSAPNFIPRLLLLSLLIVSIPLTSSQSDANTTNPSPSPPSDSDLCNGVFVSYTHTKGSKIPPNDTANQPYRFESVITVLNHGRDELKSWRVFVKFAHREILVSASNAVLSDGSSLPVSVENGTVFAGYPSSDLKSAIQTAGDVTQMQARVELVGTQFGVAPPNVPLPKNITLATDGWKCPKATQKGTNVLQVCCIPDPDYDNREIIDNEFLPRKDGDLTIMYDVVRSYSSNYMAQVTMENHNPLGRLDNWKLSFDWMRDEFIYTMKGAYPSIVDSSDCVDGPQAKHYQDLDFSNVLSCARRPTVIDLPPTKYNDSTFGLIPFCCRNGTILPRSMDPSKSSSVFQMQVYKMPPDLNISALSPPQNWRINGTLNPDYKCGPPVRVSPSQFVDPSGLPSNRTAFASWQVVCNITQPKDASPRCCVSFSAYFNDSIVPCKTCACGCSSNKAARACSATAPSLLLPQQALLVPFENRTELTVAWAYLKQRPVPNPMPCGDNCGVSINWHLATDYRGGWTARVTVFNWGETDFVDWFTAVQMKNAAPGFEKAYSFNASTIGINGKNNTIFMEGLPGLNYLVAERDGENPLKNPRIPGKQQSVMSFTKKLTPGINVPGGDGFPSKVFFNGEECSLPTILPMRSSQHRKHISVFLLALPVLALLILRA
What are the official names of this protein?
COBRA-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the COBRA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GUAB1_MYCLE
Sequence: MRFLDGHQPRFDLTYKDVFIVPHRSDVASRFDVDLSTYDGSGTTIPVVVANMTTVAGQRMAETVARRGGLVILPQDLPIATVQQAVEFVKSRDLVIDTPVLLTPNDSVSDATTLIHKRAHGVAVVAFEGRPIGLVRESSCLGVDRFTRVRDVATTDFVTAPVGTDPRKIFDLLEHAPIDVAVLTNADGTLAGVLTRTGAIRAGIYTPATDARGRLRIGAAVGINGDVAGKAQSLAEAGVDVLVVDTAHGYQVKTLEAIKCVASLNLGVPLVAGNVVSAEGTRELLNAGATIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARKLNRHVWADGGVRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRHDQPYKESYGMASKRAVVARTVADSSFDRARKALFDEGISTSRMGLDPDHGGVEDLIDHITSGVRSTCTYVGASTLAELHEKAVVGVQSAAGFAEGHPLPSGW
What is the function of this protein?
Involved in the purine-salvage pathway.  Catalyzes the NADPH-dependent conversion of GMP to IMP.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate reductase, GMPR.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
Protein: SRF5_ARATH
Sequence: MTQKLVRLVIVSLAITVTLLQAKTDNQEVSALNVMFTSLNSPSKLKGWKANGGDPCEDSWEGVKCKGSSVTELQLSGFELGGSRGYLLSNLKSLTTFDLSKNNLKGNIPYQLPPNIANLDFSENELDGNVPYSLSQMKNLQSINLGQNKLNGELPDMFQKLSKLETLDFSLNKLSGKLPQSFANLTSLKKLHLQDNRFTGDINVLRNLAIDDLNVEDNQFEGWIPNELKDIDSLLTGGNDWSTETAPPPPPGVKYGRKSSGSKDGGGITAGTGMVIAGACLGVLVLIIVLIALVSKKKSSLSPHFIDEDNSHHTPKFKSLTSHGSAQELRVDFGNDYKDGKSGDSGDENIHRIGSKGLKHYVSSRVMSFTDTEFANKLNAKRTTSTRSAVEFELSDLQSATANFSPGNLLGEGSIGRVYRAKYSDGRTLAVKKIDSTLFDSGKSEGITPIVMSLSKIRHQNIAELVGYCSEQGHNMLVYEYFRNGSLHEFLHLSDCFSKPLTWNTRVRIALGTARAVEYLHEACSPSVMHKNIKSSNILLDADLNPRLSDYGLSKFYLRTSQNLGEGYNAPEARDPSAYTPKSDVYSFGVVMLELLTGRVPFDGEKPRPERSLVRWATPQLHDIDALSNIADPALHGLYPPKSLSRFADIIALCVQVEPEFRPPMSEVVEALVRMVQRSSMKLKDDLSSSYRAHDDYDY
What are the official names of this protein?
Protein STRUBBELIG-RECEPTOR FAMILY 5, Leucine-rich repeat receptor kinase-like protein SRF5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1111_HALSA
Sequence: MGLEEDIESLEEEIANTPYNKSTEAHIGRLKAKLAEQKEKLEAQQSGSGGGGGYAVEQHGDATVALVGFPSVGKSSLINAMTNADSEVGAYEFTTLNVNPGMLEYRGANIQLLDVPGLIEGAAGGRGGGKEILSVIRGADLVIFVLSAFEIEQYDRLAEELYNVNIRVDAEPPSVTVRRKGKDGIDVNTSGELELDSDTVKGILRERGFINANVTIRGNPSVDRLIDGVMDNRVYMPSLVTVNKVDLIEPSYAGTMKDALRDHGVSPDDAIFISAAEEKGLDVLKERMWRALGLIRIYMDKPGRGVDREEPLIIRRGETVDDAVQKLGGTLDERFRFARVTGPSAQHDDQQVGRDHVLEDEDVLRVVARR
What are the official names of this protein?
Uncharacterized GTP-binding protein VNG_1111G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
Protein: RS2_PROM3
Sequence: MAVVTLSEMMEAGAHFGHQTRRWNPKMSRYIYCARNGVHIIDLVQTAICMNNAYKWTRSSARSGKRFLFVGTKKQASEVVALEATRCGASYVNQRWLGGMLTNWTTMKARIDRLKDLERMESSGAIAMRPKKEASVLRRELERLQKYLGGLKGMRRLPDVVVLVDQRRETNAVLEARKLDIPLVSMLDTNCDPDLCEVPIPCNDDAVRSVQLVLGRLADAINEGRHGTNEQRGADDNDD
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: HUS1_SCHPO
Sequence: MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSGELQLSVNIPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDPEDEHTAVLTYYISTYVD
What is the function of this protein?
Essential in controlling the S-M checkpoint that couples mitosis to the completion of DNA replication.  It is also required for the response to DNA damage.
What are the official names of this protein?
Checkpoint protein hus1.
What is the protein family that this protein belongs to?
Belongs to the HUS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.