PharMolix/UniProtQA huggingface dataset:
Protein: SSPN_BACC4
Sequence: MGNPKKNSKDFAPNHIGTQSKKAGGNKGKQMQDQTGKQPIVDNG
What are the official names of this protein?
Small, acid-soluble spore protein N, SASP N.
What is the protein family that this protein belongs to?
Belongs to the SspN family.
What are the subcellular locations of this protein?
Spore core.
Protein: EIF3I_ARATH
Sequence: MRPILMKGHERPLTFLRYNREGDLLFSCAKDHTPTLWFADNGERLGTYRGHNGAVWCCDVSRDSSRLITGSADQTAKLWDVKSGKELFTFKFNAPTRSVDFAVGDRLAVITTDHFVDRTAAIHVKRIAEDPEEQDAESVLVLHCPDGKKRINRAVWGPLNQTIVSGGEDKVIRIWDAETGKLLKQSDEEVGHKKDITSLCKAADDSHFLTGSLDKTAKLWDMRTLTLLKTYTTVVPVNAVSLSPLLNHVVLGGGQDASAVTTTDHRAGKFEAKFYDKILQEEIGGVKGHFGPINALAFNPDGKSFSSGGEDGYVRLHHFDSDYFNIKI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, TGF-beta receptor-interacting protein 1, TRIP-1, eIF-3-beta, eIF3 p36.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIMV_PSEAB
Sequence: MVRLRTLVRAIAAASVLTSGMAHGLGLGEITLKSALNQPLDAEIELLEVRDLGSGEVIPSLASPEEFSKAGVDRLYYLTDLKFTPVVKPNGKSVIRVTSSKPVQEPYLNFLVQVLWPNGRLLREYTVLLDPPLYSPQAAASAPQAPVSAPRATGAPRTPQAPAPVRTTAPAGSDTYRTVSNDTLWEIAQRNRTDRVSVPQAMLAFQELNPGAFVDGNINRLKSGQVLRIPTEQQMLERSPREALSQVQAQNQSWRGSRNPAAGTAGARQLDATQRNAAGSAPSKVDATDNLRLVSGEGKASKGADKGGKGDSKAIADTLAVTKESLDSTRRENEELQSRMQDLQSQLDKLQKLIQLKDAQLAKLQGQLGAEGQGAAQPNAALPDASQPNAAAQAPAQPGTPAAAAPTPAPAGEAPAAPAQPPVAPPPAPVAEKPPAPAVPAPAPVQAAEQPAPSFLDELLANPLWLAVIGGSALLALLVLLMILSRRNAQKEKEEAQAFAADAGEEQEDALDLGKDGFDDLTLDEPEPQVAAAAPQVEKTTAQTSDALGEADIYIAYGRFNQAAELLQNAIYDEPQRTDLRLKLMEVYAEMGDREGFARQENELREIGGAQPQVEQLKSRYPAMVAVAAVAGLAGAKLAQDELDSFSLDDLSLDDSGHAAKPDAAGQDLDDAFDLSLDDLGGGDLGSDDVQADLKSDSGALDDLTLDSDLDLAASTAADKPVDDLDFGLDFAELAETPSQPKHDDLGDFSLDLDAPEDKLSDDDFLLSLNDEVPAAAPANNEFTLDTEAAEEPALSLPDDFDLSLADEPTEPAAPEKGEDSFAAQLDEVSAQLDELASNLDEPKSAAPSFSAEDAAVASALDGDADDDFDFLSGADEAATKLDLARAYIDMGDSEGARDILDEVLAEGNDSQQAEARELLERLA
What is the function of this protein?
Inner membrane hub protein that plays both cAMP-dependent and cAMP-independent roles in twitching motility.  Regulates intracellular cyclic AMP (cAMP) levels through the activation of adenylate cyclase CyaB.  Plays an essential role in a number of virulence mechanisms including type IV pilus (T4P)-mediated assembly and twitching motility as well as cAMP-dependent virulence gene expression.  Mediates also type II secretion (T2S) of lipases and proteases.  In addition, mediates the cAMP-independent localization of multiple T4P structural and regulatory components to the cell poles (By similarity).  This role in directing proteins to the cell pole is not restricted to type IV component and involves other proteins such as the diguanylate cyclase DgcP (PubMed:32080219).
What are the official names of this protein?
Motility hub protein FimV.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AHI1_RAT
Sequence: MEQETPEKVDSAQEKVRGKSQPADDSEDSREKAGTEGTGELTEAYELQVAEEMAKEIKKKIRRKLKEQLTYFPPDTLLHDDKLGSEKRKKKKKKKVPVPAKPETSPSDVCDSAAEGEQKKEGAPEGSHHREGGCSTEQNADASVPENTKPKPKKMKKKPKAVSEDNEETNGDGVHEITGRDSPVHPKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEKDNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFDECPKVILFFEILDFLSMDEIKNNSEFQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSQPNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSYRSMMALQEERGTPVYCERHRETSSVDTEPGLEDSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTARFHPATRELVVTGCYDSMIRIWKVDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIAVWDTYVKVTDVQHSVRHWTINKEIKETEFRGVPVSYLEVHPNGKRLLIHTKDSTLRIMDLRILAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSELPFKSTIRDISYHPFENMVAFCAFGQSEPILLYIYDFQVAQQEAEMLKRYSGTVPLPGIHLSEDALCTCPKLPQQGSFQIDEFVNTENNSSRKIQLVKQRLETVTEVIRSCAAKVNKNLSITSPPPGPAKKPRVKQSFVLTTDQIIHQFGVPQTAFISIERRPFMRPVDPPPMVVALYDYTASRSDELTIHRGDIIRVFFKDNEDWWYGSLGKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKAKMEKPPASRKSLIKDRFLDSRLGSKPMGHSEKGRDQNFEERGHKSDMEMKKSEPTVRKVTLIE
What is the function of this protein?
Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium.  Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Involved in neuronal differentiation.  As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development.
What are the official names of this protein?
Jouberin, Abelson helper integration site 1 protein homolog, AHI-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell junction, adherens junction. Note=In the retinal photoreceptor cell layer, localizes at the connecting cilium.
Protein: MUKB_YERPB
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVVNSRHQRVVVGVRLQQVAGRDRKVDIKPFTIQGLPTAIQPTEILTELVAERQARVLSLPELKERVEAMEGVQFKQFNSITDYHSLMFDLGVIPKRLRSSADRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDSALVLRRDLFSSRKQLVTEQYRHVEMSRELAEQSGAESDLETDYQAASDHLNLVQTAMRQQEKIERYQSDLEELTYRLEEQSEVVSEASEQQADNEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYQQALQALERARALCQLPELTADNAEEWLETFHAKEQEATESLLQLEQKLSVADAAHSQFEQAYQLVVNIAGEVSRSEAWQTARELLRDWPSQQHLAERVQPLRMRLSELEQRLRAQQDAERLLQEFCKRQGNAYQPEELEALQRELESQVEELSLSVSDAGERRMAMRQELEQLKLKIQELTARAPVWLAAQDALSQLSEQSGEALEDSRQVTEYMQQLLERERETTVERDEIAASKRAIEAQIERLSQPSGAEDARLIALAERFGGVLLSEIYDDVTIDDAPYFSALYGPSRHGIVVPDLSLVREHLQGLDDCPEDLYLIEGDPQSFDDSVFAVEEHEKAVVVKIADRQWRYSRYPEVPLFGRAARENRLETLYQERDRLAERYATLSFDVQKTQRTHQAFSRFIGSHLAVAFDADPEAEIRLLNTRRGEIERALNAHEDQNQQQRQQFDQAKEGISALNRLIPLVSLLLDETLADRVEEITEELAEAQEAARYIQQHGVSLTKLEPLLSVLQSDPQQHEQLQESYVLAQNSQRLAKQQAFALTEVVQRRAHFSYTDSAGMLTENSDLNDKLRQRLEQAEAERTRAREQLRQYQSQFTQYSQVLASLKSSYDAKRDMLKELSQELVDIGVPADANAEARARARRDELHAALSTNRSRRNQLEKQLTFCEAEMDSLQKKLRKLERDYHQIREQVVNAKAGWCAVMRMVKDNGVERRLHRRELAYMDGDELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTAREQKLAISSKSVSNIIRKTIHREQNRIRMLNQGLQAVSFGQVKSVRLNVNVREAHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQMDMGQRLPQTIGEELLDYRNYLELEVEVYRGADGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLEMQLIIAAPENISPEKGTTYKLVRKVFQNHEHVHVVGLRGFANEMPSLPPIAAELQQGG
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: Y5833_BURL3
Sequence: MLSPCPALPPAECRDSTDLPADPPGRVLPLHRLKRRPRGWRPERPRERLLERGPAALTDDELIALLLGTGKPGHDVFATARVLVTQFKSLHGLLEATADDFEAHPGIGPARSARLVAVTEIARRMLKEKAHEKQPIDSPGAVEDYLRLKIGARPYEVFAAVYLDARHRLIDMEEITRGSLTRMAVYPREIVRRAMVHNAAALIVAHNHPSGAVQPSAEDRRLTRVLHDALALVDVRLLDHVVIGISDTFSFARAGWL
What are the official names of this protein?
UPF0758 protein Bcep18194_A5833.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: APOC1_LYNPA
Sequence: MRLILWLPVLVVVLLMVLEGPAPAQGAPDIAGTFRNIPNSLKEFGNNLKDAFENIPEATRKLMTSFAEGLKNFRIPMV
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: STS1_TALMQ
Sequence: MNSLVATPPVPPHFYEHSRFSPSRSMSTPVQQNSNRKRKAEDDGNDVDVRMSASPTNSPAFTPRPLPNRQMKRSRPNVSGRPLSLPRLLETLDTEALRSVLQAVCQRHPELGDEVVHTAPRPSVASTLQVLRNYQSTLQTSIPLGSGEYLSDYAYNRVKQHLFSLLEALSDFTPHFLPPNESQTSVSLTYLDGATDIIHGLPKWQTPRHNIGRDSAYEEIGKAWVLVIREAAKRGGGIQLQYGGWDQKLAKHNETSGGKLQDAVNELRNSLGWMGSSALPGAGASGGDQISIREQLLSGTYGMGMPLKVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome sts1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUOK2_GEOSL
Sequence: MIVPFEHVLILAGLLFALGLVCVLVWRMNLIMLLIGIEVMLNAAMLAFVGGAARWGMADGQVFSLIIMALTSAEVSLALAMVVYLHRRKKTVDADEFRELQG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAL_SULSY
Sequence: MKFFIDTADVNEIREANKLHFLDGVTTNPTLIAKVKKPFWDVVKSILAEVPDKPVSLEVASTDAEGMIKEGEKLAELGKNVVIKIPMTPEGLKAVSYFENKGIKTNVTLVFSPAQALLAMKVGASYISPFVGRLDDISHTGMDLIRQIKQIKDNYNFKSEIIVASVRNPVHVIESAMIGADIATIPYSVIAQLAKHPLTDIGLERFLKDWESVPEKPF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_BARBK
Sequence: MYEKYSPYKVFTAQEWSQFRADTPLTLTFDEIKHLRSLDDPVDLEEVQRIYLSLARLLSCHVEAIQNLFQKRQQFLHQENIKKNPFIIGISGSVAVGKSTTARILQELLKRWAFNLKVDLITTDGFLYPNAVLQKKNRMNRKGFPDSYDIKKLLHFLSAIKAGISKVSAPLYSHITYDVLEDQKVIIDHPDILIVEGVNVLQVNRFPNDKRIVPFVSDFFDFSIYVDAETDMICYWYLERFKRLRKTAFQNPESYFYRYALLSEEEALKIAENIWRTINLKNLQENILPTRSRADLILRKGKNHLVEYVALRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_PSEPG
Sequence: MSVTMTLGQLAEALGATLKGPEALQITGLATLQEAGPGQLSFLANPQYRKYLDNCQAGAVLLKAADAESFAGNALIVADPYQAYARISHLFDPKPKAVAGIHPSAVVAEDAQVDASASIGPFAVIESGARIEADVSIGAHCFVGARCVVGEGGWLAPRVTLYHDVTIGKRVVIQSGAVIGGEGFGFANEKGIWRKIAQIGGVTIGDDVEIGVNTAVDRGALSDTRIGDGVKLDNQIQIAHNVQIGDHTAMAACVGISGSTRIGKHCMLAGGVGLVGHIDICDNVFVSGMTMVTRSITEPGSYSSGTAMQPLADWRKSAARIRQLDDMAKRLQQLEKRVDTVTSGGLPTSEG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SMRD1_HUMAN
Sequence: MAARAGFQSVAPSGGAGASGGAGAAAALGPGGTPGPPVRMGPAPGQGLYRSPMPGAAYPRPGMLPGSRMTPQGPSMGPPGYGGNPSVRPGLAQSGMDQSRKRPAPQQIQQVQQQAVQNRNHNAKKKKMADKILPQRIRELVPESQAYMDLLAFERKLDQTIMRKRLDIQEALKRPIKQKRKLRIFISNTFNPAKSDAEDGEGTVASWELRVEGRLLEDSALSKYDATKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTATTQETDGFQVKRPGDVNVRCTVLLMLDYQPPQFKLDPRLARLLGIHTQTRPVIIQALWQYIKTHKLQDPHEREFVICDKYLQQIFESQRMKFSEIPQRLHALLMPPEPIIINHVISVDPNDQKKTACYDIDVEVDDTLKTQMNSFLLSTASQQEIATLDNKIHETIETINQLKTQREFMLSFARDPQGFINDWLQSQCRDLKTMTDVVGNPEEERRAEFYFQPWAQEAVCRYFYSKVQQRRQELEQALGIRNT
What is the function of this protein?
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).  Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:8804307, PubMed:29374058).  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex).  During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).  Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element (VDRE).  May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer (PubMed:14698202).  Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation (PubMed:12917342).  Interacts with AKIRIN2 (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, 60 kDa BRG-1/Brm-associated factor subunit A, BRG1-associated factor 60A, BAF60A, SWI/SNF complex 60 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SMARCD family.
Protein: MURC_ACIAD
Sequence: MSPTTPADQAKKLIKVPEMRRIKHIYFVGIGGAGMCGIAEVLKNQGYKVSGSDIKASKTTAHLEQKGIKVYIGHTADNLKAVDVLVVSTAIDPENPEVKAAIENRIPVVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENMDPTYVIGGLLNRTGVNAALGASRFIVAEADESDASFLYLQPMAAIITNVDADHMDTYGGSFDKLKDTFVEFIHRLPFYGLAVVCGDDHNVREIMPRFGRPTLTYGFNEDNDIRAVDVVQEGMQSHFTVLRKDREPLRLTVNQPGLHNILNALAAIGVATDEGVSDAAIARALEGFSGVGRRFQVQGEFELGEGSVKLVDDYGHHPKEVEATIKAARQSHPDRRLVMMFQPHRFSRTRDCFDDFVEVLSQVDQLLLLEVYPAGEKPIVGADSRTLARSIRLRGDVEPILVDPVEGNLPNIIQKVLQPNDLLLTQGAGNVGAISVDLAQQQLYLK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3496_CAUVN
Sequence: MLMVISPAKSLDFTAPQTVLPLTTPELKAQIAELSKVTRKLTAADLKRLMHISDALATLNRERFQAFDPEVEEGLQAVIAFNGDVYAGLNARELDRPALEWAQDHLRILSGLYGVLRPFDALQPYRLEMGTRLKTKKGANLYDFWGETISRTLNQAAEGHADPTLVNLASQEYFGAVDAKALKLPVVTCHFKEEKGGELRVLGFFAKKARGRMARYIIDNRIDQAEALKGFDLDGYRFQPGLSTSADWVFARPQP
What are the official names of this protein?
UPF0246 protein CCNA_03496.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CAL1_CALGI
Sequence: QRPEYPVWREKGAV
What are the official names of this protein?
Calotropin-DI.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: RPP_XYLFT
Sequence: MPVVTVYRHGGKGGVAPMNSSHIRTPRGDVQGWSPGAVRRNTQFLMCVREDKLTGAGFALTLTVRDCPATAQEWHKMRRAWEKRMLRAGMIRLHWVTEWQRRGVPHLHCAIWFSGTVYDFSLCIDAWLAVASSCGAALRGQHGRIIDGVVGWFQYVSKHAARGVRHYQRCSDNLPEAWKALTGRVWGKVGDWPLFSELRIDLQDHRQDGDGGFFAYRRLVRSWRVSDARRAGDRYRLRSARRMLTCSDTSRSRAIGFMEWGSL
What are the official names of this protein?
Putative replication protein PDa0002.
Protein: E2F8_XENTR
Sequence: MEEGSKENCGFNGSPMGSRSPPKQLTSAASVLGEIQIAAANLKTPTKPQERNNADPWTPTANLKMLISAASPEIRNREREILEEQFSGDELEKTLPSRKEKSLGLLCHKFLARYPSYPNPAVNNSICLDEVAGELSVERRRIYDIVNVLESLHMVSRLAKNKYIWHGRLNLSKTFDALKKVGEENRYGEQIQLLRKREQEECDSQNSPNAETQKPLAKQPEVGFVELPGLEFRAASVNSRKEKSLRVMSQRFVMLFLVSDPQIVSLEVAAKILIGEDQLEDLDKSKFKTKIRRLYDIANVLTSLNLIKKVHVTEEKGRKPAFQWTCPELCTDDQENRSSPAALTPVAIDLSSPKENCAKNLFASGGKTFTRHPSLIKLAKSIENDRRKINSAPSSPIKSGDGSSSAASKMAQLAAICKQQLQQSRDQTKVKLKVSACKAKSTVKQPGGSDKNQTPTYCRAIPLLHPHPSAAPPYTVIVQPPQEQTLSRQSPPALGYTNRTPPEAPLQGGRHEGDGTSHSEDHSAQERHPKRLPESDRGCTSKRMKSSAVDDVTETLYPSGYLIPIHLAPVAPEPSKENTGPSSENKLFTSPIPGVFPLKLMFSPGPVTAVPVMSRGGQHVGGGSGSASRSPSPGMFTFALQNRELISAGLPQGATVSPRNGRGQEELSAASVLNCKHVSPVPYHGQPFTVFALQQSAVPVTPKGYHSLQETFFRTPGGMGCSPPESARKLDVGTDD
What is the function of this protein?
Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells.  Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'.  Directly represses transcription of classical E2F transcription factors such as e2f1.  Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC-3' and mediating repression of G1/S-regulated genes.  Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator (By similarity).
What are the official names of this protein?
Transcription factor E2F8, E2F-8.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_CLOD6
Sequence: MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRVGISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKSIKNLVKRTDISI
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RS13_BUCBP
Sequence: MARIAGINIANHKHVVVALMDVYGIGKTRSKLICLRTNISESIKILDLTKDQLELLRCEVLKFVVEGDLRREVTLSIKRLQDLNCYRGSRHRKKLPVRGQRTKTNARTRKGPRKLMKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ISPF_SALG2
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SFR1_HUMAN
Sequence: MAEGEKNQDFTFKMESPSDSAVVLPSTPQASANPSSPYTNSSRKQPMSATLRERLRKTRFSFNSSYNVVKRLKVESEENDQTFSEKPASSTEENCLEFQESFKHIDSEFEENTNLKNTLKNLNVCESQSLDSGSCSALQNEFVSEKLPKQRLNAEKAKLVKQVQEKEDLLRRLKLVKMYRSKNDLSQLQLLIKKWRSCSQLLLYELQSAVSEENKKLSLTQLIDHYGLDDKLLHYNRSEEEFIDV
What is the function of this protein?
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (PubMed:21252223).  Acts as a transcriptional modulator for ESR1 (PubMed:23874500).
What are the official names of this protein?
Swi5-dependent recombination DNA repair protein 1 homolog, Meiosis protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFR1/MEI5 family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with ESR1 in the nucleus.
Protein: TRUA_VIBCM
Sequence: MRIALGIEYDGTHYYGWQRQREVKSVQEALEKALSKIANHPVEVQCAGRTDAGVHGTGQVVHFDTTAERQMVAWTMGANANLPKDIAVRWAMAVPDEFHARFSATARRYRYVIYNHVYRPGILNSGVSHYHGELDVEKMQQAGQYLLGENDFTSFRAVHCQSRSPWRNVMHLNVTRHGRYVVIDIKANAFVHHMVRNITGSLIAVGRGEQKPEWIQWLLAQKDRTLAAATAKAEGLYLVSVDYPAHFGLPEMPIGPLFLPDNLN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CN028_HUMAN
Sequence: MKTLFEEIKASIKNNYNQDRSFCRPVLPWGGVFTIKAGRKAVSCTPLYVEIRLKNTCTIDGFLMLLYVILNENENFPRELSLHFGREFVDCFLYLMDTYSFTTVKLLWIWDKMEKQQYKSEVHKASLIIDLFGNEHDNFTKNLENLMSTIQESYCSNWRCPTRVQEDQQRTININPPQEIPHGNLIRLAVNELFCSKIELCEEHGCGGLREFSQRIFCHGAPPFVVLNMQHWKSEDLAYVPYYLDLSDHKYLLEGATLFNKEEHHYSAAFQIGGHWMHYDGLRNVNLILLNKPPEFLLLSSLVYIRATEK
What are the official names of this protein?
Uncharacterized protein C14orf28, Dopamine receptor-interacting protein 1.
Protein: CSPL1_MICCC
Sequence: MDDFDPTVTNSPKFRLIAVQCLFSITAFAAMLSQRHGLAGPDEMTLEECGPQACGYQKFSNFKFLIAVCIIYAVFSLVVMAAYLLQRVPPPVTELTAYTVMNVLLFAAFAMSATSCNITIVDPVYPVCKRATSAKASIAFAFFTWLAVCFSMLFTYKEWRDVDYHVPGSGAYEFVPGVTSGSSRSSYPPQASSSSYA
What are the official names of this protein?
CASP-like protein 0U1, CASPL0U1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.