PharMolix/UniProtQA huggingface dataset:
Protein: HPM1_SCHPO
Sequence: MQANGFSFGFYDEPNNLNGQDVGADSLPSVAIESDSLGHMLKYIPEKLSYARVSGLGHTFVQRELWDVKMQLMEQDDSIESDDKLKVLDGCNDLVPNVYEGGYKTWECSLDLANEIKKIDVVKNNLTTVLELGCGSAIPILSCFQEFYKHRIPCTLVFQDFNVDVLRYVTLPNLLLNWYFCTQEHDSSEKHGTIDVSPSLLQEFSDDLARTNIYCEFLCGCWSEEMQLLIQRTYGDHYFSLVLASETIYSLPSLENFLYMLLKNTKNLALVAGKDLYFGVGGSILEFNSRLQKLVDDPNSLKAIKTSTQNVGRSIVYWEKEFPPSNIDSSPQSPLPGSL
What is the function of this protein?
Protein-histidine N-methyltransferase that mediates methylation of target protein on His residues.
What are the official names of this protein?
Histidine protein methyltransferase 1, Methyltransferase-like protein 18 homolog C1071.05.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UNC1_CAEEL
Sequence: MSNKERTEPQWVTPSSNQDVPPDYETIGTIFGYALQALSWILIIVTFPFSMCVCLKVIKEYERVVIFRIGRLVFGGARGPGMIFIIPCIDTYRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRTSDPIASVNNVDDAIYSTKLLAQTTLRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVERVEVKDIRLPQQLTRAMAAEAEAAREARAKVVAAEGEQKASRALKEAADVIQANPVALQLRHLQALNSIAAEHNSTIVFPVPVEMFGAFMKKDQ
What are the official names of this protein?
Protein unc-1, Uncoordinated protein 1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Co-localizes with unc-9 at the gap junctions formed between PLM and other neurons.
Protein: NUOL_ECOLI
Sequence: MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALVTAFIGVDFFANGEQTYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTDPKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWATLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLVTAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKGVTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLAAWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLNSMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit L, NADH dehydrogenase I subunit L, NDH-1 subunit L, NUO12.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATA_BURCM
Sequence: MHAKSLTELRAALAAKECSAVELAQLYLKRIDAARDLNAFVHVDADLTLAQAKAADAELARGAGGALTGLPIAHKDVFVTRGWRSTAGSKMLANYESPFDATVVARLQAAGMVTLGKTNMDEFAMGSSNENSAFGAVKNPWDTNAVPGGSSGGSSAAVAARLAPAATGTDTGGSIRQPASFAGVTGIKPTYGRVSRYGMIAFASSLDQGGPMAQSASDCALLLNAMSGFDERDSTSLEREDEDFTRHLGQPWAAGNDAGKPLAGLRIGLPNEYFGDGLADDVRASIDAALKQYEALGATLVPVSLPKTELSIPVYYVIAPAEASSNLSRFDGVRFGHRAAQYGDLLDMYKKSRAEGFGPEVKRRILVGAYVLSHGYYDAYYLQAQKIRRIIAQDFQEAFKSCDVIMGPASPTVAWDLGSKGDDPVQMYLADIYTLSVSLAGLPGMSVPCGFGASANAKRPVGLQIIGNYFNEARMLQVADAFQRATDWHKQVPAGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DPO3E_RICPR
Sequence: MSSLREIILDTETTGLDPQQGHRIVEIGAIEMVNKVLTGKHFHFYINPERDMPFEAYKIHGISGEFLKDKPLFKTIANDFLKFIADSTLIIHNAPFDIKFLNHELSLLKRTEIKFLELTNTIDTLVMARNMFPGARYSLDALCKRFKVDNSGRQLHGALKDAALLAEVYVALTGGRQSTFKMINKPDEINNLAVKCVDVQQIKRGIVVKPTKEELQKHKEFIDKILIQA
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).
What are the official names of this protein?
DNA polymerase III subunit epsilon.
Protein: LDHA_ELEMC
Sequence: MSTKEKLISHVMKEEPVGSRNKVTVVGVGMVGMASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTHKIVGDKDYSVTANSKLVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVLGSGTNLDSARFRHLIGEKLNLHPSSCHAWIIGEHGDSSVPVWSGLNVAGVSLQGLNPQMGTEGDSENWKAIHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESILKNLHKVHPVSTLVQGMHGVKDEVFLSVPCVLGNSGLTDVVHMTLKAEEEKQVQNSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOR1_CAEEL
Sequence: MTINIKYSSKFSSSKTSSSEELKPKTYIPAYYQPPVSMPKYYVNWLRIKLSLNKLKNIRAIYLFDQCQNFNQYQESSRKFSAGQVSSLTPWYSNFSNYSTVILRMKDTSLPPLENPSNGGTYLFNLITVFPSIALSFNYSWRGDTGPSISIFSFSLSVLFFSLFPQHKNICARAWCRPFRRSLSFSLRFIMSSEPASSSTEKVPEEPHPHSIKHKFQGPQFVIPRALSDYVLNVNNQTPESYEKALNAKYGRDDYITLCLHVTSLCTEYGPLDDGPEYVLLCDSRARVDKLIEDLVKLLEIDTDYVQLELHGGKRLHLQKPDAVLRDIAYKQSNEGSDKFFLEMKLVPSESMKAKIMKQEEEEEKARKHGQYQQYQEYHQQHQAMNDGQSSSSVPSTSSPSCSSEANRKEMETVREPAGPSELMRAINAPVAPAPVVIKIETPVALPEEDETLMDDDEMPSLTVEAPSEEASFEAEQPSPQVPQASIEGPSQQQQIPGTSQQKRQVARGSRTNMISYHDLPPGTGNAPPMACPQVTLKLEKNVPFEAKIRAVAGYTRKPISEVQKMRPSDLESIFHSICIASVQRIKRRNELVQQLQEINAQSCKSPTMTMNKKFTLAKAYQRVQNEIEKIDREQILPQQYMNMPPMPPQGQQRLPPPAYPPGILPPQQNRQQGVPPQFQRSPQFMIGPDGQRYAHPYMQLPNSNQRARILNTSSVQPSEEVRNRLVKIEAMAMNMAQLNPPRPPPPQPPHRALQGELQFLRPGAPDPCNFRPDSKQTYNNTYVTVASPATLTNSIIPWHFPPYEKSGRLNVSNTIKAINEYRLLCNSRQADPASFLEFYFLGDPMPHFNKILSIADYNMYLSRRRCDEADVKIHRMSHSDQLQLYLLELQSDESNVEKWKTFYRIMQWDLPLNNEFPRILLPSSLDIGRPVVDRKKKSIDQVMNHIHRMHSQRPPSMGNSSTSSEASSTSPTNAATATSSPASNRPTTSTAQPPTLNPT
What is the function of this protein?
Acts synergistically with sop-2 to maintain the transcriptionally repressive state of homeotic genes throughout development.  Not required to initiate repression, but to maintain it during later stages of development.  Also required to repress expression of other genes.  Binds RNA in a sequence-independent manner.
What are the official names of this protein?
Sop-2-related protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Forms subnuclear bodies. Sop-2 is required for nuclear localization.
Protein: GSA_ACISJ
Sequence: MTHNTDLNLPLFERAKALIPGGVNSPVRAFRAVGGTPRFITRAQGAYMWDANGQRFIDYIGSWGPMILGHGHPAVLEAVQKAALEGFSFGAPTEREVELAEEIIRHVPSMEMIRLVSSGTEAGMSAIRLARGATRRNKIIKFNGCYHGHADSLLVKAGSGLATFGHATSAGVPQEVVQHTLVLEYNDVAQLEEAFTLHGPDVACVIMEPIAGNMNFVRASVPFMRRARELCTQHGALLVIDEVMTGFRVALGGAQSLYAQAIPGFKPDITVLGKVIGGGMPLAAFGGSRAVMEQLAPLGPVYQAGTLSGNPVATACGLATLREIAKPGFYDALGARTRALIDGLAGAASAAGVPLCGDTQGGMFGFFLLPQLPQNYPEVLNTDGMRFNTLFHGLLDGGVYIAPALYEAGFVSAAHTEQDIADTVAVARDVFQKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_BURPS
Sequence: MVFDELITEFDRGLRSIAGVSRMSRPVPKPAAAAPAELSAAERKHAAGLMRVNHVGEVCAQALYQAQKLTTSSAGLKEMFEHAAREEEDHLAWTAHRLKDLDSRPSLLNPLWYAGALAIGVVAGRLGDKMSLGFMAETERQVESHLDGHLSELPAADVESRAIVEQMRADEVKHGKSATDAGGIELPMPARMLMRAASKVMTSTAYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS20_ANAD2
Sequence: MANTASAEKRNRQAQKRRARNVQVRTGVKSAVKKLREAIAKGDPAATQVALKSAEKTIGKAASKGVLHKNAASRKISRLAKAAAKPAAAAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RSAD1_DICDI
Sequence: MINKIVKNVIENQFKGYNKLKDLPISLFVYWPYCSKICPYCNFNKYRDSDKVDHERMSKSLSRELESFVKNIYLNSNENSFIRERPITSIYFGGGTPSLAKISTFVETIETMKKLFPSSLSIEDIEITLEVNPDQKDLKNLLKDFKKYVGVNRVSLGVQSLVDKDLHFLGRTHNRIQAEESIKIARDLFDHVTFDLIYSRTIDQTLEQWRNELRYALNLADGNGHVSLYTLTFEQGTSFYRRLSSKGNKFKIIPPDDQKSSDLYDLTVCEAEAMGFQQYEISSFASSHNQKGKHNLNYWRSGDFIGIGPGASSRLTTLNNNNNNNNQISRYSFKNILHPKEWMEKLNSKEILCNAFIEDEFNPTIPLTNFEVAEEMLLNGLRTIEGVQLSTFTFQTNGLTFDQFLNMKQVEILQEQGFLILEPTCLKLTGNGRKLLDTIIPKILKY
What is the function of this protein?
May be a heme chaperone, appears to bind heme.  Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity (By similarity).  Binds 1 [4Fe-4S] cluster.  The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (By similarity).
What are the official names of this protein?
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial, Putative heme chaperone.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AROK_STRAW
Sequence: MTVPRVVLVGPMGVGKSTVGALVAERLGCAYRDTDDDIVTAEGRTIADIFVDEGEPVFRAIEKRAVHTALAEHDGVLALGGGAILDADTRALLAGHRVVYLSMEVDEAVKRTGLNAARPLLAVNPRRQWRELMEARRHLYTEVARAVVATDGRGPEEVAQAVLDALELKEA
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_WHEAT
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFSSVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KNATM_ARATH
Sequence: MDVKKDENSILENMKQEINHSLKEEAQEEEEILKKRISSHPLYGLLLHSHLNCLKVCSGDFDSPEIMNTADDLALSKLSLHPDSSSEATSSELDQFMVLFFFSPCQNIFTQQKTTFHVLLFFPLQINLTFKYSKFILPRKKQ
What is the function of this protein?
Transcriptional regulator involved in leaf proximal/distal patterning.  May act by sequestering BELL transcription factors.
What are the official names of this protein?
Protein KNATM, KNOX Arabidopsis thaliana MEINOX protein.
What are the subcellular locations of this protein?
[Isoform KNATM-B]: Cytoplasm. Nucleus.
Protein: RECF_RENSM
Sequence: MYLEQLSLTDFRSYQQADLGLEPGVNVFIGSNGLGKTNLVEALGYLASLSSHRVSQDGPLIRFGAEQALIRGNLVRGTQRLGLEVEINASRANRARINRANPVRAREILGLCRTVLFAPEDLSLVKGDPGNRRRFLDDLLQSLHPRFAGLRADYERVLKQRNALLKSARGHSRSRQAPSADFLSTIEVWDQHFANHAAQLLSARLKVLEQLKPEMSRAYQELTDGSKELSARYRSSLDGYQEDSDDAAEIHDDEAASLVSASVESLTEHYLLALAAVRQREIERGLTLIGPHRDEVELGLGQAPARGYASHGETWSVALALRLASYYVLKADQEIDGADPILVLDDVFAELDSSRRSKLAHMVAGAEQVLVTAAVDDDVPAELSGRRIRVSAIGVVDD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STAA8
Sequence: MIHGIGVDLIEIDRIQALYSKQPKLVERILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKIDYEGFIVHVSISHTEHYAMSQVVLEKSAF
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UC07_MAIZE
Sequence: IILELAAVDSASGKLLINGNFK
What are the official names of this protein?
Unknown protein from spot 168 of 2D-PAGE of etiolated coleoptile.
Protein: FRITZ_MOUSE
Sequence: MSFCLTELHLWSLKSTLHIADRDIGVYQYYDKKDPSVSATEHGNLEEKQRLAESRDYPWTLKNRRPEKLRDSLKELEELMQSSPCVLSKWKSKYICQLLFGSGVLVSLSLSGPQLEKVVIDRSLVGKLISDTISDALLTDSFIILSFLAQNKLCFIQFTKKMDSLDGNKRLEKLSALDLKISYYDIPGPANRTIDRHLAVNSTQDLVVCWWPLVSDDVWPWTPVSSEKDRANMLLLGFTQGGLEVLSFVRTEWSPLDVHFGTKQPYQVFTVECSVSVDKEPMADSCIYESVRNKLHCVSVTRIPLRSKAISCCRNSTEDKLIVGCEDSSVILYEAHRGVTLLAQAELRPSLISCHPSGAILLVGSNQGELQIFDIALSPINIQLLAEDYSPKETLQFKKFFDVSSSLVQMQWMAPPVVFQKPKRGEICDLLFLRFNKGPLGVLLFKLGILTRGQLGLVDLILQYIHYSEVYEAISILRSMDWDTLGQQCLIGMGTIVNHLLRQRLTPEREAQLEASLGTFYAPTRPLLDTTILEYREPVSKYARRLFHHLLRYKRFEKAFLLAVDIGARDLFMDIHYLALDMGELALAEVARRRAHDIDVESVSSGVELLGPLDRRDMLNEGFASSALMPEGENKFPGLLPSIGSTHMQTLQQKIPNGPSSRWAIERRTEEEEEEEEEEEEELCTDSSGATTWNAEGELKEDQRKQDIGDVGSLRMVHFGLV
What is the function of this protein?
Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements.  Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).
What are the official names of this protein?
WD repeat-containing and planar cell polarity effector protein fritz homolog, mFrtz, Homolog-13, WD repeat-containing and planar cell polarity effector protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat fritz family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Protein: SYS_SHEPA
Sequence: MLDPKFLRSELEMTAERLATRGFILDVERLSKLEETRKSLQVATEELQASRNAISKSIGQAKAKGEDVAPIMAQVGSLGEELDAKKTELAALLEELNAIAMSVPNLPDESVPTGADESENVEVRRWGTPKEFDFAVKDHVELGENIGGLDFKNAVKITGSRFIVMKGQIARMHRALAQFMLDLHTTEHGYTEAYVPLLVNEDSLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDTIVEEDNLPIKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQLVKPEDSMQALEDLTGHAEVVLQKLGLPYRTMVLCTGDMGFGSAKTYDIEVWLPAQDTYREISSCSNMQDFQARRMQARYKGKTDKKPSLLHTLNGSGLAVGRTLVAVLENYQNADGSITVPEALRGYMGGLKKIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLGD_SHIBS
Sequence: MKVTFEQLKAAFNRALISRGVDSETADACAEMFARTTESGVYSHGVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTTAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_HAEI8
Sequence: MSQNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGDLRVRVSFDADKGTITISDNGIGMTREQVIDHLGTIAKSGTKEFLTALGQDQAKNSQLIGQFGVGFYSAFIVADKVTVKTRAAGEEADKAVLWESAGEGEYSVADIEKKSRGTDVILHLREDEKEFLNEWRLREIIGKYSDHIGLPVEMLTKEYDDEGKECGEKWEKINKSDALWTRSKNDVSDEEYKAFYKHLSHDFVDPVTWAHNKVEGNQAYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKITAALRKALTKRSLQMLEKLAKDDAEKYLKFWKEFGLVLKEGPAEDFANKETIAKLLRFASTHNDGSEQTVSLEDYILRMKEGQKAIYYITADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGKQLQSITKADLDLGDLADKESETQKQQDKAFGSFIERVKNLLGERVKTVRLTHNLTDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHYLVKKVADIADETEFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARF_DROSE
Sequence: MSRWSTALQLTDIDDFITPSQICIKPVQIDKARSKTGAKIKIKGDSCFEESESGNLKLNKVDISLQDCLACSGCITSAEEVLITQQSQEELLKILQENSKNKASEDWDNVRTIVITLATQPLLSLAHRYQIGVEDAARHLNGYFRSLGADYVLSTKVADDIALLECRQEFVDRYRENENLTMLSSSCPGWVCYAEKTHGNFILPYVSTTRSPQQIMGVLVKQILADKINVPASRIYHVTVMPCYDKKLEASREDFFSKANNSRDVDCVITSVEVEQLLSEAQRPLSQYDLFDLDWPWSNVRPEFMVWAHEKTQSGGYAEHIFKFAAKHIFNEDLTTELEFKQLKNRDFREIILKQNGKTVLKFAIANGFRNIQNLVQKLKREKLSNYHFVEVMACPSGCINGGAQIRPTTGQHVRELTRKLEELYHNLPRSEPENSLTKHIYNDFLDGFQTDKSYEMLHTRYHDVVSDLSISLNINW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor GM20417.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: GATZ_SALPA
Sequence: MKEIIARHKAGEHLGICSVCSAHPLVIESALLFDLNTDNKVLIEATSNQVNQFGGYTGMKPADFRDFVYGIAQEVGFPRERLILGGDHLGPNCWQNEPAAAAMEKSVELIKAYVAAGFSKIHLDASMSCADDPTPLDPMVVARRAAVLCKAAEETANEEQKCHLTYVIGTEVPVPGGEASTIGSVHVTREVDAARTLETHQIAFRESGLEEALSRVIAIVVQPGVEFDHTQIIHYQPQAAQALSAWIKETPMVYEAHSTDYQTRQAYRALVRDHYAILKVGPALTFALREAIFALAQMENELISPEQRSRVLEVIDEVMLNEPGYWKKYYRPTWSQAMVDIHFSLSDRIRYYWPHPRIRQSVEKLIANLNNVTLPLGLISQFMPVQFERLSEGVLTPTPHNLIIDKIQDVLRAYRFGCTPDVA
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: GRPL2_HUMAN
Sequence: MEAARPFAREWRAQSLPLAVGGVLKLRLCELWLLLLGSSLNARFLPDEEDVDFINEYVNLHNELRGDVIPRGSNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWVGPENEFTASIAIRSWHAEKKMYNFENGSCSGDCSNYIQLVWDHSYKVGCAVTPCSKIGHIIHAAIFICNYAPGGTLTRRPYEPGIFCTRCGRRDKCTDFLCSNADRDQATYYRFWYPKWEMPRPVVCDPLCTFILLLRILCFILCVITVLIVQSQFPNILLEQQMIFTPEESEAGNEEEEKEEEKKEKEEMEMEIMEMEEEKEEREEEEEETQKEKMEEEEK
What are the official names of this protein?
GLIPR1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FABZ_SHEFN
Sequence: MSNQLNTMDIKEILKYLPHRYPFLLIDRVLDFTVGEHLHAIKNVTINEPFFQGHFPIQPVMPGVLILEAMAQATGLLAFKTMSTEPSPEVLYYFAGIDKARFKRVVEPGDQIHFHVKMIKERRGIGVFVGEALVDGELVCSAEIMCARREIKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBD_BACSU
Sequence: MEEYYMKLALDLAKQGEGQTESNPLVGAVVVKDGQIVGMGAHLKYGEAHAEVHAIHMAGAHAEGADIYVTLEPCSHYGKTPPCAELIINSGIKRVFVAMRDPNPLVAGRGISMMKEAGIEVREGILADQAERLNEKFLHFMRTGLPYVTLKAAASLDGKIATSTGDSKWITSEAARQDAQQYRKTHQSILVGVGTVKADNPSLTCRLPNVTKQPVRVILDTVLSIPEDAKVICDQIAPTWIFTTARADEEKKKRLSAFGVNIFTLETERIQIPDVLKILAEEGIMSVYVEGGSAVHGSFVKEGCFQEIIFYFAPKLIGGTHAPSLISGEGFQSMKDVPLLQFTDITQIGRDIKLTAKPTKE
What is the function of this protein?
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HTP reductase family.
Protein: HIS1_METKA
Sequence: MITVAVPNKGRLHEPALKLLERAGIGVEEPLGRRLKARTTDPDIEVMFVRAADIPRLVEEGVAQLGITGYDLIVEAGAEVKELLDLRFGRARLVLAVPEESDVKSPEDLDGGTVATEFPNIARQYFEDVGVDVEIIQVSGATEIMPRIGVADAIVDLCSTGTTLKVNRLRVVDELLETSARLIANPDATDGEVIRRVYLSLKGVLNADGKCLVMMNVPRERLEEFHELLPGVTGPTVSEIYGDEDMVEVYAVVNEEDVSEVVLRAKELGAEGIIVLPIERMIP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP71_TRYCR
Sequence: MFARRLRGAGSLAAASLARWQSSKVTGDVIGIDLGTTYSCVAVMEGDKPRVLENTEGFRATPSVVAFKGQEKLVGLAAKRQAVTNPQSTFFAVKRLIGRRFEDSNIQHDIKNVPYKIGRSSNGDAWVQDANGKQYSPSQVGAFVLEKMKETAENFLGRKVSNAVVTCPAYFNGPQRQATKDAGTIAGLNVIRVVNGPTAAALAYGLDKTKDSMIAVYDLGGGTFDISVLEIAGGVFEVKATNGDTHLGGEDFDLCLSDYILTEFKKSTGIDLSNERMALQRIREAAEKAKCELSTTMETEVNLPFITANQDGAQHVQMTVSRSKFESLAEKLVQRSLGPCKQCIKDAAVDLKEISEVVLVGGMTRMPKVIEAVKQFFGRDPFRGVNPDEAVALGGATLGGVLRRDVKGLVLLDVTPLSLGVETLGGVFTRMIPKNTTIPTKKSQTFFSTAAFNQTQVGIKVFQGEREMAADNQMMGQFDLVGIPPAPRGVPQIEVTFDIEPNGICHVTAKDKATGKTQNITITASGGLSKEQIERMIRDSESHAESDRLKRELVEVRNNAETQANTAERQLTEWKYVSDAEKENVRTLLRACRKSMENPNVTKDELSAATDKLQKAVMECGRTEYQQAAAGNSSSSSGNTDSSQGEQQQQGDQQKQ
What is the function of this protein?
May participate in eukaryotic mitochondrial DNA replication.
What are the official names of this protein?
Heat shock 70 kDa protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast. Note=Associated with kinetoplast DNA in the mitochondrion, in the region where kdna replication occurs.