PharMolix/UniProtQA huggingface dataset:
Protein: ARP19_TAEGU
Sequence: MSAESPEPASAEEQKEMEDKVLSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAAPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity).
What are the official names of this protein?
cAMP-regulated phosphoprotein 19, ARPP-19.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_CHLAD
Sequence: MPEHILVAVAWPYANGPRHIGHVAGFGVPADIFARYHRLRGNRVLMVSGTDEHGTPITLVADKEGTTPQAIADRYNKIIGDDLYNLGLSYDTFTRTTTANHYAVTQDIFRTLYERGYIIRQETLGAFSATTGRTLPDRYIEGTCPLCGYDEARGDQCDNCGSQLDPTDLINPRSKVDGQPPVFKPTEHFFLDLPAFAEQLHDWINRQDHWRPNVRNFSLNFLKDLKPRAITRDLEWGVPIPLPEYANRDDKKIYVWFDAVIGYLSASIEWAQNSGQPDAWREWWQNPDARHFYFMGKDNIVFHTVIWPAMLLGYGAGGQFGADPGGKYDGIPLQLPYNVVSSEFLTMEGKKFSSSRGIVIYVNDFLSRYDADALRYFLTIAGPENQDTDFTWAEFVRRNNDELVATWGNLVNRTLSNVYKNFGSVPQPGPLTPVDEQVLAEVTGGIETVGELLAAARFKAALAEAMRLAAQVNIYLSEQEPWKVIKSDHERAATIWYVALRCVDTLKIIFTPFLPFSSQRLHEYLGYNGYIAGPLTFREVTEANGRTHRVLTGDYDRWVGRWEPSVLPVGQVLRQPQPLFKKLDEKVIEEELARMQSRLG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDD_METJA
Sequence: MIYNDRLGEVMDLNTLIKIIEKVGRIEIEDIKITADELIINIPSAPPIVIPQTPSIKEKLAEEGIIEIKDVPELDWEPPVEKYPGYIREVQFGKPKSEGGRGKVVKIGGQRALYRFEEPQPNPPVVTFDIFDIPMPGLPKPIRQFFQDVMEDPCEWAKKCVKEFGADMITIHHISTDPKIKDKSPKEAAKLMEDLLQAVDVPFVIGGSGNPQKDPLVLEACAEVAEGDRCLLASANLELDYKKIVDAAMKYDHNVLAWSIMDPNMARDLNRKLVEAGLDPNRIVMDPTTCALGYGIEFSINAMVRLRLNGLKGDELVNMPMSSGTTNAIGAREAWMNNPEWGPREYRLPLWEITTGITMMMCGVDLFMMLNPISVKTLKEIGKTLTTKPGEVKLNTNNYEWIVSP
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  Probably maintains the overall quaternary structure of the ACDS complex.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit delta, ACDS complex subunit delta, Corrinoid/iron-sulfur component small subunit.
What is the protein family that this protein belongs to?
Belongs to the CdhD family.
Protein: GUF1_PLAF7
Sequence: MNYTSVNKIRLWVLIVFLILYNIKCICENISDLKKRLCFNNFSNSKKKIKKKWLAKKKKNYLTIWKNKTYTTKRRNGYGKIEYKREENKKDDYNFMNTSLYLNYISNVKNFLFNKNNNKKNKIYYHKCKKSNIIEAKINDNDTLLSDEEFRNDVDRNDKEYYNIKKEYSENVCNQNRINDLSNCSVSSNNNILNECSSEVKKEMNYPLHNELYDNLNDNTIGHLKSEKCKEKYIRNFCILAHIDSGKSTLADRFLELTNTIKKKRMQEQFLDMMCLEREKGITIKLKAVRMHYNNYVFNLIDTPGHFDFYHEVKRSLNVCEGAILLIDGGKGIQSQTLNIFFELKKHDIKIIPVINKIDLSTCLYDKIKDDLINKFNFKENEILKISAKYGKNVKMLFQRIISDIPPPINTINSFFRGVVFDSFFDQYKGVVLIIKVLNGELRKKTEIFFINSAKSYIIQEVGYLVPEMKPTDVISQGDIAYVCSNIRNCDDIQISETIVNKDIIKKNNHNEFVINFKKINLGRDKNIMQRLSDEGKQYLTHHNKGEIKGDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDENGQVKCDKNKGEIKSFQYNEVKVDERYERNKEEIIYDHEHKKEGIFNIHKNDDLIKENIKEKENFSCSIQGNDNAIPILKKTDINIKSIAANKIEASYPSVYCNIYCVNDKKSNELEMSLNKLKLNDSSFSFKKYICETLGKGFKCGFNGLLHLNIIQERIKREYNIDTIVTAPSVNYLIRVKEKYMDKRLKEKLLEKNFDIQNMHIEQMDKTSSDDCFFFMTSNVNDIPTKNVVHSIYEPYVKTNIITPEIYQKYIMNECFKRRGIFIKKEIMNDQIIFLFEMPLSEILINFLDQIKSSTKGYGSMSYENIIIYKPSELYKIHIYINKKKIDSLSFLAHKRNYEDKSRKLVSKLKTLINPHQFLIIIQAALESKIFVSEKIKPLKKNVTAKCYGGDITRRRKLIEKQNEGKKKMFEIGKVKLPPNIFTKLFDIKSE
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity).
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: AROC1_BACCZ
Sequence: MRYITAGESHGPQLTTIIEGVPAGLPLVADDINEELARRQKGYGRGRRMQIETDQVQIVSGVRHGETLGSPIALVVENRDFAHWTKIMGAEPLTEQEEKEMKRKVTKPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVAAGAVAKKVLAELGIAVAGHVIEIGGVQAKETTYRSIEELKSITEASPVRCLDEEAGNQMIKAIDDAKSNGDSIGGIVEVIVEGMPIGVGSYVHYDRKLDAKLAAAIMSINAFKGVEIGIGFEAAHRPGSEVHDEILWDEEHGYTRRTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLQSVDIDTKEPFTASIERSDSCAVPAASVVAEAVVAWELATALIEQFGLDRMDLIRENIEKHNEYARGF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 1, CS 1, 5-enolpyruvylshikimate-3-phosphate phospholyase 1.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL34_BRUAB
Sequence: MKRTYQPSKIVRKRRHGFRARMATTGGRKVLAARRTRGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: STRM1_CAEEL
Sequence: MSINMNANFLKLLTHFRRHDLTNFKSEHDTLYEKALETGDHLEVTSHYYSVMSTVIDEYFGGNFHFVPPKFEGQKLEEALKSLHCHIAEKLELSENVHCLDIGCGIGGVMLDIADFGAKLTGVTIAPNEAEIGNEKFANMGISDRCKIVAADCQKMPFEDSTFDVAYAIYSLKYIPNLDKVMKEIQRVLKPGGKFIVYDLIKTNDYDKDNKEHYKTLHHLEYACGMPSLHTQSEVEAAAEKWEMPVVERENLEETYGNRAFHYCFSASPMFMWLVSSPVIDHTIRMAEILRILPAGFKQFNRTFLCGTVNSIVGGGRMGILSGADILLFEKKKI
What is the function of this protein?
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-4 of the A-ring sterols such as lathosterone (5alpha-cholest-7-en-3-one) thereby rendering them unsuitable as ligand precursors.  May irreversibly shunt sterols away from hormone dafachronic acid production.  Dafachronic acids act as ligands and bind directly to the nuclear hormone receptor (NHR) daf-12 suppressing dauer formation and inducing reproductive growth.  By reducing the biosynthesis of dafachronic acids, this methyltransferase can regulate dauer larva formation.
What are the official names of this protein?
Sterol 4-C-methyltransferase strm-1, STRM-1, Sterol A-ring methylase-1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Protein: RL1_MICLC
Sequence: MAQRSKAYKAAKAAIGEDLYSPVEAIRLAKETNPSKTDATVEVALRLSVDPRKADQMVRGSVSLPHGTGKTARVVVFATGDRAEAARAAGADVVGDDDLIARISEGWVDFDAAVASPELMGKVGRLGKVLGPRNLMPNPKTGTVTPDVAKAVTDIKGGKIDFRVDKHSNLHFIIGKTSFEAKALVENYAAALEEILRLKPSSSKGRYISKATVATTFGPGVPMDPNVTSVDSSEL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SM3L2_ARATH
Sequence: MGTKVSDDLVSTVRSVVGSDYSDMDIIRALHMANHDPTAAINIIFDTPSFAKPDVATPTPSGSNGGKRVDSGLKGCTFGDSGSVGANHRVEEENESVNGGGEESVSGNEWWFVGCSELAGLSTCKGRKLKSGDELVFTFPHSKGLKPETTPGKRGFGRGRPALRGASDIVRFSTKDSGEIGRIPNEWARCLLPLVRDKKIRIEGSCKSAPEALSIMDTILLSVSVYINSSMFQKHSATSFKTASNTAEESMFHPLPNLFRLLGLIPFKKAEFTPEDFYSKKRPLSSKDGSAIPTSLLQLNKVKNMNQDANGDENEQCISDGDLDNIVGVGDSSGLKEMETPHTLLCELRPYQKQALHWMTQLEKGNCTDEAATMLHPCWEAYCLADKRELVVYLNSFTGDATIHFPSTLQMARGGILADAMGLGKTVMTISLLLAHSWKAASTGFLCPNYEGDKVISSSVDDLTSPPVKATKFLGFDKRLLEQKSVLQNGGNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYGQSRPKDAKLLSQSDVVITTYGVLTSEFSQENSADHEGIYAVRWFRIVLDEAHTIKNSKSQISLAAAALVADRRWCLTGTPIQNNLEDLYSLLRFLRIEPWGTWAWWNKLVQKPFEEGDERGLKLVQSILKPIMLRRTKSSTDREGRPILVLPPADARVIYCELSESERDFYDALFKRSKVKFDQFVEQGKVLHNYASILELLLRLRQCCDHPFLVMSRGDTAEYSDLNKLSKRFLSGKSSGLEREGKDVPSEAFVQEVVEELRKGEQGECPICLEALEDAVLTPCAHRLCRECLLASWRNSTSGLCPVCRNTVSKQELITAPTESRFQVDVEKNWVESSKITALLEELEGLRSSGSKSILFSQWTAFLDLLQIPLSRNNFSFVRLDGTLSQQQREKVLKEFSEDGSILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMRIHRIGQTKEVKIRRFIVKGTVEERMEAVQARKQRMISGALTDQEVRSARIEELKMLFT
What is the function of this protein?
Functions in error-free postreplication DNA repair or DNA-damage tolerance (DTT) pathway (PubMed:18310306, PubMed:21549648).  Required for homologous recombination (HR) induced by DNA double-strand break (DSB) in somatic cells (PubMed:18310306).  Required for damage-induced DNA repair, independently of MUS81 and RECQL4A.  Plays a role in synthesis-dependent strand annealing (SDSA) but not in single-strand annealing (SSA) (PubMed:20971895).  Possesses double-stranded DNA-dependent ATPase activity.  Is able to regress replication forks with preference for forks with a leading strand gap.  Is able to catalyze branch migration of Holliday junctions and is unaffected by protein blockades (PubMed:27458713).
What are the official names of this protein?
DNA repair protein RAD5A, Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 2, SMARCA3-like protein 2, RAD5 homolog A, AtRAD5a.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_JANSC
Sequence: MNIILLGPPGAGKGTQAGILVKDRGMVQLSTGDMLRAARTSGTEMGNLVAGVMDRGELVTDEIVIGLIREQLEAGGSGFIFDGFPRTLAQADALADLLAEVGQTLDHVIAMEVNDEALVGRIVNRAKEAAAAGQPVRADDNEESLKIRLMEYYKKTSPLLGYYHAKEQLRWVPGLGAIDDVAKGIADVLDA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y041_RICCN
Sequence: MPKTDKLKQLIDIVNYYKQLEDNAKTIGNFLETVKKLNQLLETPKSENKLENLLNYLKYIYLTSNFPKKKIWLHLILQNGLTIYLPRGI
What are the official names of this protein?
Uncharacterized protein RC0041.
Protein: Y2468_BACAH
Sequence: MNQVRKWNIIGGRVIKTGIAVFLTVLVCEFFNIPTIFAVITAIVTIEPTATDSIKKGLVRFPASTIGSAYAMTFTFFLGHQALSYALAAMFTIVTCQKLRLHAGTLVATLTAVAMIPITADHYFTAFLIRLATTSTGIIVSTVVNFFILPPHYVKTISGCTEELFVKTANVMEEWLTALMDGKVIKKETTYNLSKLTVLLHKAVQFVQYEQKDWKYHRHTKKEMRSFLLVQKQLHLLQQIIYHIDNLARAPIETCDWSQNEKEILRRTIHSIISILRNYCEKIDEEHFKLIDELDKQFWTNKNDLAHCKPNQYHHHFSSESIILFEVLSIHDMLEELKQIFEKYESENQLNCSVH
What are the official names of this protein?
UPF0421 protein BALH_2468.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH10_TREDE
Sequence: MKVKPLGDRVLVKPDAVETKTAGGIIIPDTAQEKTQRGVVVAVGDDKEKIKVSVGQKVIHDKYAGTQIQIDGVDHLILKSNDLVAVVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPT2L_HUMAN
Sequence: MPAAFPCVFPPQSLQVFPQMIVKVWEKQSLPLPGLRGSPVERLYLPRNELDNPHKQKAWKIYPPEFAVEILFGMVSVDSLLFVLSSPHWWLHLAQGSFWMSEGGFSLCHPGWSVVAQSLLTSTSAFCVRAILLPQPPE
What are the official names of this protein?
Putative phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2P1.
Protein: CAF1A_HUMAN
Sequence: MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIPCKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGDGVPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYEVDSDEEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKAKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEEQTPKASKRERRDEQILAQLLPLLHGNVNGSKVIIREFQEHCRRGLLSNHTGSPRSPSTTYLHTPTPSEDAAIPSKSRLKRLISENSVYEKRPDFRMCWYVHPQVLQSFQQEHLPVPCQWSYVTSVPSAPKEDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDGQIGAEDMDGFQADTEEEEEEEGDCMIVDVPDAAEVQAPCGAASGAGGGVGVDTGKATLTASPLGAS
What is the function of this protein?
Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair.  Assembles histone octamers onto replicating DNA in vitro.  CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.  It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
What are the official names of this protein?
Chromatin assembly factor 1 subunit A, CAF-1 subunit A, Chromatin assembly factor I p150 subunit, CAF-I 150 kDa subunit, CAF-I p150, hp150.
What is the protein family that this protein belongs to?
Belongs to the CHAF1A family.
What are the subcellular locations of this protein?
Nucleus. Note=DNA replication foci.
Protein: CYOE_ACIBS
Sequence: MLKKYLFLTKPGILFGNFITTLGGFFLAAQGSIDILLLLLTLIGTTLVVASGCVVNNVIDQDIDTKMQRTQNRALVKKTISPTVALVYAFVLGVMGFSILWFGVNGYAFLFAMIGFIVYVGFYSLWTKRTSIHQTVIGSISGASPPVIGYTAVTHQFDVAALLLFLAYALWQMPHSWAIAIYRFDDYKNAGIPILPVARSIYRTKIECVIYILLFAAVLNGLYCFGYTNVFFLITFNALTAYWFYLSIIGFKAENDQLWAKRFFLYSVILITLLSLSFSFTYQSPAPNLPLF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLND_ACIB3
Sequence: MINTSPLLNYVSSHHDIKAINQWRTDVEKQLQDSYENGQSIREIIKARSDLVDEALVFLWKHAELDQSKLGLFAVGGYGRREMLPYSDVDIMILSEDEISEENEKRISTFISSLWDVGNFKPGISVRTIQSCVEQAATDLTVATTLIEARLITGNTQLAKWPRRIVSQTWTDKTFYDAKMAEQAKRYHQHNNTESNLEPDIKNAPGGIRDINQIGWIAKRHFRVNRIYDLVHLGFISEFELAVLEEAESFLWEIRHHLHRLAKRDENRLLFDHQREIAAKFGYVRQEGQPVNYGVEQFMKRYYRTAQQVSTLNEMLLAYFSESVITPRLPNYERKIEVVNDHFKIVDNKLAVQHHKIFAEHPSAILELFYILANRPDIEGIRARTLRLLILAAKRINQSYRDNPEHQALFMSIIRSPYRLYDTLVAMKRYGVLGNYIPAFGQIMGLMQYDLFHIYTVDAHTLLLLRNLNRFREPEFAKEFPVVSSVFQRLARQDIVFIAALFHDIAKGRGGDHSELGAEDAIEFGRAHGFTERECKLIAWLIQNHLLMSLTAQKKDISDPDVVKDFAEKLGDMEHLDYLYTLTVADINATNPKLWNTWRASLMRQLYTHARDVIRTGLGRPVDYQMLIEDTKFAASELLVNNFALADVEKVWQELGDEYFIKESADEIAWHTQAILKHGDNPEPLVLLRAHRKAAQDAVQIFIYTRDQPNLFATTVAVLDRMNLDVQDAKIITASTAFSLDTYVVLDRFGTLLTDPEREETVKNALVKALSQPDQYPGLMQRRIPRQLRHFDIENTVDVTLNEALQQNMVEISTLDHPGLLARVGGLFMMQGLDIHSARIATLGERAEDIFFVTKKDGKPLNNEEVKLFSEKLKAALDEASNQICQH
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: CITX_ECO55
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: RL20_TREPS
Sequence: MSRSLSSNGRVRRRKRILKLAKGFRGRCGTNYKAAKDAVSKALAHSYVARRDRKGSMRRLWISRINASVRTQGLSYSRFMNGLLQAGIALNRKVLSNMAIEDPGAFQTVIDASKKALGGGAC
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MTLD_EMENI
Sequence: MGKAIHFGGGNIGRGFVGEFLHEAGYEVVFVDVVDDLITSIQNTPSYEITEISEDGEKTKKITNYRALNSKSHEADVVQEIATADIVTCAVGPRVLQFIAPVIAKGLESRNVSTPLTVIACENAINATDTLRGHIEKKTKPEIISERAVFANCAIDRIVPNQPPNNGLNVRIEKYWEWVVEQTPFKEKGVAHPNVSAIHWVDKLDPYIERKLFTVNTGHATTAYYGHLAGKKTIADALHDPKIRENVHKVLDETASLIINKHGISEQEQKEYVDKIISRISNPYLEDGVERVGRAPLRKLSRNERFIGPASQLAERGLKFDALLGAIEQALRFQNVEGDEESKELAKILKEKTAEEATSELTELEKDHPLYSHVLERVRTVQQESK
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase, M1PDH, MPD, MPDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: GORK_ARATH
Sequence: MGRLRRRQEIIDHEEEESNDDVSSRRGKLSLAETFRWLDSSEHRRIETDGHNDYKYIIHPKNRWYKAWEMFILVWAIYSSLFTPMEFGFFRGLPERLFVLDIVGQIAFLVDIVLQFFVAYRDTQTYRTVYKPTRIAFRYLKSHFLMDFIGCFPWDLIYKASGKHELVRYLLWIRLFRVRKVVEFFQRLEKDTRINYLFTRILKLLFVEVYCTHTAACIFYYLATTLPPENEGYTWIGSLKLGDYSYENFREIDLWKRYTTALYFAIVTMATVGYGDIHAVNLREMIFVMIYVSFDMVLGAYLIGNITALIVKGSNTERFRDKMNDLISFMNRKKLGRDLRSQITGHVRLQYDSHYTDTVMLQDIPASIRAKIAQLLYLPYIKKVPLFKGCSTEFINQIVIRLHEEYFLPGEVITEQGNVVDHLYFVCEGLLEALVTKTDGSEESVTLLGPHTSFGDISIICNISQPFTVRVCELCHLLRLDKQSFSNILEIYFHDGRTILNNIMEEKESNDRIKKLESDIVIHIGKQEAELALKVNSAAFQGDFYQLKSLIRSGADPNKTDYDGRSPLHLAACRGYEDITLFLIQEGVDVNLKDKFGHTPLFEAVKAGQEGVIGLLVKEGASFNLEDSGNFLCTTVAKGDSDFLKRLLSSGMNPNSEDYDHRTPLHVAASEGLFLMAKMLVEAGASVISKDRWGNSPLDEARLCGNKKLIKLLEDVKNAQSSIYPSSLRELQEERIERRKCTVFPFHPQEAKEERSRKHGVVVWIPSNLEKLIVTAAKELGLSDGASFVLLSEDQGRITDIDMISDGHKLYMISDTTDQT
What is the function of this protein?
Major selective outward-rectifying potassium channel of the guard cell membrane.  Involved in regulation of stomatal movements according to the water status.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by depolarization.  Conductance of the channel is modulated in a potassium-dependent fashion.  May interact with the cytoskeleton or with regulatory proteins.
What are the official names of this protein?
Potassium channel GORK, Guard cell outward rectifying K(+) channel, AtGORK.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZITR_LACLM
Sequence: MSLANQIDQFLGAIMQFAENKHEILLGECESNVKLTSTQEHILMILAAEVSTNARIAEQLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEKAIPVAKEHAAHHEKTLSTYQELGDKFTDEEQKVISQFLSVLTEEFR
What is the function of this protein?
Zinc-responsive regulator that represses expression of the zit operon in the presence of zinc.  Acts by binding two palindromic operator sites overlapping the -35 and -10 boxes of the zit promoter.  Could be a sensitive sensor of intracellular zinc to efficiently respond to zinc variations in the environment.
What are the official names of this protein?
Transcriptional regulator ZitR.
Protein: LEXA_ALIFM
Sequence: MKPLTARQQEVFDLIKAKIDDTGMPPTRAEIARELGFRSANAAEEHLKALARKQVIEIIPGASRGIRILLQDADDHDEELGVPLIGQVAAGEPILAQEHVESHYKVDPGMFKPQADFLLRVNGESMKDIGIMDGDLLAVHKTQDVRDGQVVVARVDDDVTVKRLERKGSMVFLHAENEEFSPIEVDLTSQSLSIEGLAVGVIRSTTWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: METAS_ECOUT
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCD_COXBU
Sequence: MSILIDKETRVLCQGFTGKQGTFHSEQAIEYGTQMVGGVTPGKGGQSHLGLPIFNSVHEAVEETSADATMIFVPAPFCKDSIIEAVDAGVRLVVCITEGIPVLDMLEVKAYLRQHPDVRMIGPNCPGVITPGECKIGIMPGHIHQRGKVGIVSRSGTLTYEAVNQTTQMGFGQSTCVGIGGDPIPGTSFIDVLEMFEKDSQTQAIVMVGEIGGTAEEEAAEFIQSNVKKPVISYIAGVTAPPGKRMGHAGAIIAGGKGTAADKYAALEAAGVFVVKSPAEIGKGVAEATGWSTH
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.