PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_VIBC3
Sequence: MSLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGAWQVAQLARHPQRPYTLDYLKHIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQKGRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDALDHENLLERRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y445_VIBVY
Sequence: MRLIVVSGHSGAGKSVALRVLEDMGYYCVDNLPVNLLESFIQSVSESKQNVAVSIDVRNIPKKLKELTTTLQKLKSSIDLSILFLDADKATLLKRYSETRRVHPLSLSDECHTLDQAIDLEKKMLKPLKEIADILLNSSNQSLHDLSEDVRYRIEGKERNKLIMVFESFGFKFGLPTDADYVFDVRFLPNPHWEPALRPMTGLDAPIKTFLESHDEVLELKRQIQTFIEHWLPLLEKNNRSYLTVAIGCTGGKHRSVYLTQQIGEYFAAMGHTVKIRHTTLEKRNKE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein VV0445.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SNA29_CAEEL
Sequence: MSRNPFDDDYRPSAASSTMPVKSYTTMGHYSGEDEADYYEREIEKTLQESLDSTERSRRHLENSEKIGTSTAQQLLEQREKLENTEKNLDEIHRTTQMTQRNLNSLKSFFGGMFKNKFTKKPQEPTETPTVPQSKSASRLSETATNLSSGGGSATFSGPSGQRTLTESSRSAIKGTRWEAMDNQIDENLDMMSANLRNLQRLGADLGKEVDSQNEMLDRIQYKAERNDGIVRDQDKQMQKILGTGASTSQTTAESLTPSMDTSTKMSLMMKATSLWK
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.  Plays a role in the processing and secretion of the aspartic protease hrg-7 from the intestine (PubMed:28581477).
What are the official names of this protein?
Soluble NSF attachment protein 29.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Synapse, synaptosome.
Protein: EFTS_MESH2
Sequence: MSQIDKMAKIKKLREISDAPFVDCKKALENSDYDIDLAINWLNKNGKSKALKKSDRIAAEGLVLAKKDANSVLVFELNSETDFVAKNQNFINLQQKIGELLLANDFVNLEDALLIQDEAGRSISELMILATATIGEKITLRRVFKTKYSLEQSVEVYTHSNGQIAVITILKGGNLEIAKNISMHVAALNPQYILKVEVPNEKLQEIQLEVEKKAFAEVKNFEKKPENVRVGILKGMIDKQLSEFVLELQPLATDSAVTVEKYLAQNSATLEKVVRFEVGEGIQKQNVDFSAEVNQQIQEFQKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_MOUSE
Sequence: MGRSESQMDITDINAPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVNGKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW
What is the function of this protein?
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (By similarity).  Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (By similarity).  Catalyzes cleavage of bradykinin, substance P and neurotensin peptides (By similarity).  Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (By similarity).  Involved in the degradation of the atrial natriuretic factor (ANF) (By similarity).  Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).
What are the official names of this protein?
Neprilysin, Atriopeptidase, Enkephalinase, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RDRP_I60A0
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAHQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVIESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFKSKSMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTVSLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQLALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: OBL_OBELO
Sequence: MSSKYAVKLKTDFDNPRWIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKEIAFPQFLDGWKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTRQHLGFWYTLDPEADGLYGNGVP
What is the function of this protein?
Ca(2+)-dependent bioluminescence photoprotein.  Displays an emission peak at 470 nm (blue light).  Trace amounts of calcium ion trigger the intramolecular oxidation of the chromophore, coelenterazine into coelenteramide and CO(2) with the concomitant emission of light.
What are the official names of this protein?
Obelin, OBL.
What is the protein family that this protein belongs to?
Belongs to the aequorin family.
Protein: ANMT_RUTGR
Sequence: MGSLSESHTQYKHGVEVEEDEEESYSRAMQLSMAIVLPMATQSAIQLGVFEIIAKAPGGRLSASEIATILQAQNPKAPVMLDRMLRLLVSHRVLDCSVSGPAGERLYGLTSVSKYFVPDQDGASLGNFMALPLDKVFMESWMGVKGAVMEGGIPFNRVHGMHIFEYASSNSKFSDTYHRAMFNHSTIALKRILEHYKGFENVTKLVDVGGGLGVTLSMIASKYPHIQAINFDLPHVVQDAASYPGVEHVGGNMFESVPEGDAILMKWILHCWDDEQCLRILKNCYKATPENGKVIVMNSVVPETPEVSSSARETSLLDVLLMTRDGGGRERTQKEFTELAIGAGFKGINFACCVCNLHIMEFFK
What is the function of this protein?
Involved in the biosynthesis of acridine alkaloids.  N-methyltransferase with a strict substrate specificity for anthranilate.  No activity with anthranilic acid methyl ester, anthraniloyl CoA, 3- or 4-amino-benzoic acid, salicylic acid, catechol, eugenol, caffeic acid, quercetin, theobromin, theophyllin, putrescine and nicotinic acid among others.
What are the official names of this protein?
Anthranilate N-methyltransferase, RgANMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: TR117_MOUSE
Sequence: MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 117, T2R117, mT2R54.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NFUA_VESOH
Sequence: MFNITDKAKVYMADLFAQQDEKDLGLKVDIEKAGTPAATVIFNFCFPKELSKTYQKFEYKGFDVYINKLNFVYLKDSEVALKDSSVGKKLIITAPNAKGEEPKEDAPLEEKIKYVIAADITPGLASHGGFVELVGITKQIDVILNFGGGCQGCSSVKSTLEQGVEAQLKARFPEIKSVRDVTNHANTDNAYM
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: ALDH2_YEAST
Sequence: MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFDNVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN
What is the function of this protein?
Cytoplasmic aldehyde dehydrogenase involved in ethanol oxidation.  Required for pantothenic acid production through the conversion of 3-aminopropanal to beta-alanine, an intermediate in pantothenic acid (vitamin B5) and coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Aldehyde dehydrogenase [NAD(P)+] 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_NANDO
Sequence: MRINPTTSGPGVSALEEKNQGRIVQIIGPVLDVAFPPGKMPNIYNALVVKGQDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEDDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLTETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLDVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MED20_YARLI
Sequence: MVTILQYSADVTATTISTYRSELSAQLAQNLGKWSFELKMYKPNPASIGRSEHHNGNIPQGQQEAAAADQEIGGVAALYTLTQAHSKGDMVYVTQGSAVQGQPGVVVSDSFDMVLQNKMKSIWILRQTLRGDGAEYELMGDAYGRVKVRLANVFLQGTFRGLLFQYEYEGDTLDDRQQQHLMEFIQSSGFPSSNLIIGGNGSGLVQTGTQFVEALAQK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 20 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMC_AQUAE
Sequence: MRKVFKLNKVKVKELLKKVESEYRRDAEIILSYLLKVSPSQIPLMYAREIPEEIVKRFFKQMKERKKGIPTAYVIGEWECMGRVFKVKKGVLVPRPETEILIERTLELIPQDREMVGFELGSGTGCISINLLIERPKLVMYATDVNPDAVELTKENAKLHKVDDRLFVFLGNAFEPVKGMKFDFIVSNPPYIPENFWEILPEEVKKEGYTSLIGGKKGWEFYELIAEEGTKHLKENGFIALEIGHDQGKVVKELLEKKCFKVNIFKDYAGFDRVVIAQRWS
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, M.AaoHemKP, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: VSI1_TRYBB
Sequence: MLRALLPSTTLALILAGGGHAAVGDAFPAFAVLCAAWDAATNKQIKPWSEDRELPELNDIYNMNMSIASEEWQTIFDGQAEQQTWSQFAQANAGKYKGIDWKQNWDRWRKQRQQTKDAGGAWQTKNHRPEWAATPRDVRPVILAIAEEATELSRKLEPPRTADGKDLIAEINSKLASARCSGELKAAAGNIGCTGPEGTPDKTTTCTTAKAGGSIGHDMLCLCSVAEATDKCSSTGVGDAVPNSGEKLRSNGFQHIVARCPKGPESGTLPQAIDLALAMLATALGTQQPGSNNMILGKSGGGTCTATNSACVDYHEKFSKQQAGITGIPWVALLQQARALYGTYVDAKLAAQTARQQIVMLAGQAKREYRRPAGSLKDPAGVIQEQATNRRRHGADDTNQCTSNNATADECPETRCEYDSEKNECRPKKGTETTATGPGERTTPADGKANNTVSDSLLIKTSPLWLAFLLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein ILTAT 1.21, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: Y1869_SHEB5
Sequence: MLCAVYKSSRKADTYLFVKKRDCFDDVPAPLMEMFGVPKLVMVFPIAKRDALGMADIQKVRAAMEENGFYLQIPPPQVNLLAEHKLSLGIKD
What are the official names of this protein?
YcgL domain-containing protein Sbal_1869.
Protein: RL35_HELPY
Sequence: MPKMKTNRGASKRFKVKKNLIKRGSAFKSHILTKKSPKRKANLNAPKHVHHTNAHSVMSLLCRA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: BIVM_XENLA
Sequence: MPNIEADRVTSVPENNDCKSKSQPLRNNLHETVKSYSIQGAATANIEPPAERPYPWGCPVTHTKEKFYTICADYAFLNQATSLCKSSSSVCSSSSEDKSALSNTINYIDLQTSESDSVYNEDASLESLSSNLGTRPLAWEIDKSDFSTMTSKLKRSGVKKQTPKKKPDRKAKPLRDCPQHLILDDVKQRKVLDLRRWYCISRPQYKTSCGISSLVSCWNFLYSTLGAGSLPPITQEEALHILGFQPPFEEIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGETAVGALSKLTQGLKEDSTAYVYHCQNHYFCPIGFEATPVKASKAYRGQLFPHEVEYWILIGEPSRKHPTIHCKKWADIVTDLNTQNPEYFDIRHTERGLQYRKTKKGGNLHCLLAFQRLSWQRFGPWPLQLGTLRPEPQPPVQGRRIPKSESEDNVSKKQHGRLGRSFSAGFQQELAWKRMCNIRERRGSGSPESDTDYEGND
What are the official names of this protein?
Basic immunoglobulin-like variable motif-containing protein.
What is the protein family that this protein belongs to?
Belongs to the BIVM family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SCP23_ARATH
Sequence: MARIHLIIILLVISSTSSSSSSLREQEEDMIKALPGQPQVGFSQFSGYVTVNESHGRSLFYWLTESPSSSHTKPLLLWLNGGPGCSSIGYGASEEIGPFRINKTGSNLYLNKFTWNTEANILFLESPAGVGFSYTNTSSDLKDSGDERTAQENLIFLIKWMSRFPQYQYRDFYIVGESYAGHYVPQLAKKIHLYNKAFNNTPIINLKGFMVGNGDMDKHYDRLGAAMYAWSHAMISDKTYKSILKHCSFTADKTSDKCNWALYFAYREFGKVNGYSIYSPSCVHQTNQTKFLHGRLLVEEYEYDPCTESYAEIYYNRPDVQRAMHANLTSIPYKWTLCNMVVNNNWKDSEFSMLPIYKELTAAGLRIWVFSGDTDAVVPVTGTRLALSKLNLPVKTPWYPWYSEKQVGGWTEVYEGLTFATIRGAGHEVPVLQPERALTLLRSFLAGKELPRSY
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Putative serine carboxypeptidase-like 23.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: XPR1_MUSSP
Sequence: MKFAEHLSAHITPEWRKQYTQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDVQKESSGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVIHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIGLNITLGFAAVFKLETDRTVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGILWCLSLLACFFAPISIIPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHKYSYGVRAIVQCIPAWLRFIQCLRRYRDTRRAFPHLVNAGKYSTTFFTVTFAALYSTHKEQNHSDTVVFFYLWVFFCIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITATTFKPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLDNCGEFRAVRDISVAPLNADDQTLLEQMMDQEDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
What is the function of this protein?
Plays a role in phosphate homeostasis.  Mediates phosphate export from the cell.  Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity).  Potential receptor for xenotropic and polytropic murine leukemia retroviruses.
What are the official names of this protein?
Xenotropic and polytropic retrovirus receptor 1.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VALA_STRHJ
Sequence: MTMTKQSSLSPGSRLYDYTTQDGAAWRVSALKEVSYDVVVQPRLLDPANPALADALSSGTTPARRLIVIDATVRSLYGEQLAAYLAGHDVEFHLCVIDAHESAKVMETVFEVVDAMDAFGVPRRHAPVLAMGGGVLTDIVGLAASLYRRATPYVRIPTTLIGMIDAGIGAKTGVNFREHKNRLGTYHPSSLTLIDPGFLATLDARHLRNGLAEILKVALVKDAELFDLLEGHGASLVEQRMQPGEGGTGGAALTVLRRAVQGMLEELQPNLWEHQLRRLVDFGHSFSPSVEMAALPELLHGEAVCIDMALSSVLAHHRGLLTEAELGRVLDVMRLLHLPVLHPVCTPDLMRAALADTVKHRDGWQHMPLPRGIGDAVFVNDVTQREIEAALLTLAERDRVPRWRALHGAVDMGV
What is the function of this protein?
Catalyzes the cyclization of D-sedoheptulose 7-phosphate to 2-epi-5-epi-valiolone.  Involved in validamycin biosynthesis.
What are the official names of this protein?
2-epi-5-epi-valiolone synthase, EEVS, Sedoheptulose 7-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. EEVS family.
Protein: SYS_ACIAC
Sequence: MLDILLLRKDLDSAIARLETRKKPQAFLQVEAFQSLESERKTLQTRTEELQSRRNQLSKQVGQLKARGENADAVMAEVGGLKAELENSAARLEQIQAELHTLLVAVPNLPHESVPVGSDESGNVEVRRWSPDGQDPKPLGFPAKDHVDLGEPLGLDFDMGVKLSGSRFTVMKGPIARLHRALAQFMLDVQTREHGYTECYVPYVVNADSLRGTGQLPKFEGDLFAAKKGGQDGEPVPDNAALYLIPTSEVPLTNFVRDQVVPESELPIRLTAHTPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQITHPDRSYEALEEMTGHAEAVLQKLGLPYRVMSLCTGDMGFGAAKTYDLEVWLPAQNTYREISSVSNCEAFQARRLQARFKNAQGKNELVHTLNGSGLAVGRTLVAVLENYQQADGSVAVPEALRPYLGGDSVLR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_BURP1
Sequence: MTTREFDYIICGAGSAGNVLATRLTEDPGVTVLLLEAGGPDYRFDFRTQMPAALAYPLQGRRYNWAYETDPEPHMNHRRMECGRGKGLGGSSLINGMCYIRGNALDYDNWATHKGLEDWAYLDCLPYFRKAETRDVGPNDYHGGDGPVSVTTSKPGVNPLFEAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPRGRRASTARGYLDQARARPNLEIVTHALADRILFSGKRATGVTFLHGSARVTAHARREVLVCSGAIASPQLLQRSGVGPGEWLRELDIPVVLDLPGVGRNLQDHLEMYIQFECKEPVSLYPALKWWNQPKIGLEWMLNGTGLGASNHFEAGGFIRTRDDDPWPNIQYHFLPVAINYNGSNAIEMHGFQAHVGSMRSPSRGRVKLKSRDPHAHPSILFNYMAEALDWREFRDAIRATREIMRQPALDRFRGRELNPGADLKSDNELDTFVRARAETAFHPSCSCKMGYDDMAVVDNEGRVHGIDGLRVVDASIMPIITTGNLNAPTIMIAEKIADRIRKHKPLERSNAQYYVANGAPARGGKPARAPAVV
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: SYA_BIFLO
Sequence: MRTADIAKRYLDYFAKHDHLIVPSASLISPNPTTLFTIAGMVPFIPYLMGEQTPPKRRMASNQKCVRTLDIDEVGKTTRHGTFFQMLGNFSFGDYFKEEAIHYAWELLTTSQDEGGYGFDPEKLWMTTFTDDDEARSMWINEGVDPEHIQKMGMEDNFWTTGGPGPGGPCSEIYVDRGPAFGKEGGPIADENRYIEIWDLVFENYEVDNVKSKTDLHIVGELENKNIDTGAGLERLAYLLQGKNNIYETDEVFPVIEAAEQLSGLKYGENEDADVRFRVVADHVRSALMIMSDGVRPSNVGRGYVLRRLLRRTVRSMRMLGVTDPVLPTLFPTSKAAMEASYPELNDTFHEVSESAYGEEDAFRRTLETGTTILDVAVNKAKSDSAEPVVAGEDAFKLHDTYGFPIELTLEMAAEQGVKVDEAKFRELMAEQKSRARADALKKRHNVDLSVYDDFKKTLVSPIDFLGYTDMSARAKVIGIMQEGKGSVPAVTGPANVEVILDRTPFYAEAGGQLADQGEILSDDGAVLEVDDVQKPIKDLIVHQCRLTEGTLVVGAEVNANIDLARRGAIARSHTATHMVHKALREELGPQATQRGSEDAPNRLRFDFQWSKAPAKSVISAVEERVNDKLRDNLAVTTKEMKFDDAIALGAMHLFGEKYGDIVRVVSIGEDGWSRELCGGTHVDHVGKIGMVNILSEASIGSGVRRVDAVVGQGAYDFNAREHALVSQLSDKLNARPDELAERVNALLAKLKESDRRLASMYESQLAASVPALVADTKNSAAPVKVAVKNVGHFGAVDALRKTVLDVRAQLGEDAPVVVALAGVNEDDKPMVAVATNEAARKAGIKAGDLVRGAAKVLGGGGGGKPDFAQGGGVDASKIDEALEALKHEAQKA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_GEOMG
Sequence: MDKKKHGSHAGAHHTDEPAAETVAPAAEGAPAAADRVKELEEALAAKEAEAAANWDKFVRERADLENYRKRTQKEKEELLKYGNESLIVEILPVVDNMERALDHSDDDSASAVIEGVRMTLNMLLSTLKKFGVTVVEAEKGTPFDPAVHQAMCQVENTDVPANSVVEIFQKGYLLNERLIRPAMVSVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.