PharMolix/UniProtQA huggingface dataset:
Protein: CPSF5_PONAB
Sequence: MSVVPPNRSQTGWPRGVTQFGNKYIQQTKPLTLERTINLYPLTNYTFGTKEPLYEKDSSVAARFQRMREEFDKIGMRRTVEGVLIVHEHRLPHVLLLQLGTTFFKLPGGELNPGEDEVEGLKRLMTEILGRQDGVLQDWVIDDCIGNWWRPNFEPPQYPYIPAHITKPKEHKKLFLVQLQEKALFAVPKNYKLVAAPLFELYDNAPGYGPIISSLPQLLSRFNFIYN
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7.  Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing.  The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA.  Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function.  Binds to chromatin.  Binds to, but does not hydrolyze mono- and di-adenosine nucleotides.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 5, Nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21, Nudix hydrolase 21.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. CPSF5 subfamily.
Protein: GCOA_STRGG
Sequence: MSQITLPAFHMPFQSAGCHPGLAETREAAWEWAAAEGLDLSVPARRKMIRTRPELWISLIFPQATQAHLDLFCQWLFWAFLVDDEFDDGPAGRDPLMCERAIARLVDVFDGAAPNGPMERALAGLRDRTCRGRSPQWNRQFRRDTAAWLWTYYAEAVERAAGQVPSRAEFAKHRRDSVAMQPFLCLHEITAGIDLPDSARSLPAYIALRNAVTDHSGLCNDICSFEKEAALGYEHNAVRLIQRDRGSTLQEAVDEAGIQLARIAERVQRAERELIEEIEAAGIDGPTRTALERCVRDYRGLVRGDFDYHARAERYTRPDLVELDERDSLSRHFAA
What is the function of this protein?
Sesquiterpene cyclase that first catalyzes the cyclization of farnesyl diphosphate (FPP) to the bicyclic sesquiterpene (+)-beta-caryophyllene intermediate, and then its conversion to (+)-caryolan-1-ol via a second cyclization and the addition of a water molecule.
What are the official names of this protein?
(+)-caryolan-1-ol synthase, (+)-beta-caryophyllene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: CYB_EOSRO
Sequence: MLNMRKSHPLLKIINHSLIDLPAPSNISMWWNFGSLLGICLSLQIITGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFLHVGRGMYYGSYNYLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGLNSNADKIPFHPYYTIKDMLGFIIMFLFLMILVLFSPDMLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILILLPLLHTSAQRSLMFRPISQCLFWILVADLFTLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPLAGILENKIMKV
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNME_STAEQ
Sequence: MDFDTITSISTPMGEGAIGIVRLSGPQAIEIGDILYKGKKKLSEVETHTINYGHIIDPETNETVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRILELTMTYGARMAEPGEYTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTDFLLEQSKRIKEEINQLLETGAQGKIMREGLSTVIVGRPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRDTEDIVEKIGVERSRKALSEADLILFVLNNNEPLTEDDQTLFEVIKNEDVIVIINKTDLEQRLDVSELREMIGDMPLIQTSMLKQEGIDELEIQIKDLFFGGEVQNQDMTYVSNSRHISLLKQARQSIQDAIDAAESGIPMDMVQIDLTRTWEILGEIIGESASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y436_MARMM
Sequence: MKDLMGLMKQAQAMQQKMTEAQARLAETEVTGEAGAGLVRVVLTAKGDMVSIHVDKSLMDPDEPEILEDLLKAAHADARRKGEEAQQDIMKDAAGGLQLPPGMQMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Mmar10_0436.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GPPA_SHIF8
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENDLSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDISGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQENQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: RPOC2_PROMA
Sequence: MTSTSPKSRKSSSKRKGSKKKAARSKNVIPPLSKTPPSFRNCVVDKKSLKQLVAWAFKNHGTAVTAAMADNLKDLGFKYATQAAVSISVDDLKVPEAKQDLLGQAEEQITATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKKNFNHNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREEDCGTTRAILINAEDGRFGNRLVGRLVAEDIVDQEDAVIAKRDTAIDPELSKKIEKANVNGVMIRSPLTCEATRSVCRKCYGWALAHNQLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAETGVVRSNLAGKVEFGPKARVRGYRTPHGVEAQQAEVDFLLHIKPTEKGKGQKVEISSGSLIFVEDGQEVDADVTLAQIAAGAIKKSVEKATKDVICDLAGQVRYEEAIQPKEVTDRQGNITLKAQRLGRLWVLAGDVYNLPPNAKPVIASNANVQAGKVLAEASQSSEFGGEVRLRDSIGDSREVQIVTTSMTLKDYNLLEESNHSGEIWNLEANDGTRYRINSIPGSKIGNNEVIAELSDDRFRTKTGGLVKYAPGLAIKKARSAKNGFEVSNGGSLLWIPQETHEINKDISLLMIQDRQWIEAGTEVVKDIFSQTAGIVTVTQKNDILREIIVRSGEFHLCTDSNILERFDNEGQIVNPGETIAKGIKPEAMVFVQTIETTEGKGVLLRPVEEYTIPDKAQLPELSHVTQQQGPSLGLKATQRLGYKDGELIKSVEGVELLKTQLILETFDTTPQMTVDVEVTEDQSTKTIQRLRLVILESILVRRDTISDSSHGSTHTELQVKDQQIVKAGDIVATTQILCKEKGIVQLPEMKEDEPIRRLIVERQEDTVTLTAASKPVVKIGQRVIDGDLLSNEEPINCCGEIEAIKENKVTLRLGRPYMVSPDSVLHVKNGDLVQRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRDSAILCKRRGIVEINQGDDDDSVVVKVIESDDLIEEYPILLGKNVMISDGQEVKAGELLTDGPVNPHELLECFFGDLRDRKPLMEAAQEAIAKLQHRLVTEVQNVYKSQGVAIDDKHIEVIVRQMTSKVRIEDAGDTTLLPGELIEIRQVEDTNQAISITGGAPAEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFVEELRAEAGPHPDILAEDPAGYRRIQNLRPDYTVEMPSSPAAANLTSVLDDPSDADLEATRNRHGIDPSTSNFAAFARPSGDDNFQEDQSPDPAALEGLQEEGLLSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: SCED_STAAW
Sequence: MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSNDQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGTNGADMSAQAPATNNVAPSAVQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKSSEGSSVNVNAHLKQIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVKLYNTGGAGHWVTA
What is the function of this protein?
Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells.
What are the official names of this protein?
Probable transglycosylase SceD.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. SceD subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRHL3_MOUSE
Sequence: MSNELDFRSVRLLKNDPVSFQKFPYSNEDEAWKTYLENPLTAATKAMMRVNGDEESVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKKFYHSMDYEPDLAPLESPTHLMKFLTENVSGSPDYTDQLKKNNLLGLEGVLPTPGKTNTVPPGPSKLEASSMDSYLLPASDIYDNGSLNSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPDPPCPEDYPGLKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLALSSSKVKSVVMVVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSGFRGNETTYLRPETDLETQPVLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGLPEENICKVYKKCKRGILVNMDNNIIQHYSNHVAFLLDMGELDGKIQIILKEL
What is the function of this protein?
Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin.  Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes.  Essential for epidermal differentiation and barrier formation at the end of embryogenesis with TGM3 as critical direct target (PubMed:21081122, PubMed:20654612, PubMed:25347468).  Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events such as eyelid fusion and epidermal wound repair (PubMed:21081122).  Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation after injury (PubMed:25347468).  Plays unique and cooperative roles with GRHL2 in establishing distinct zones of primary neurulation.  Essential for spinal closure, functions cooperatively with GRHL2 in closure 2 (forebrain/midbrain boundary) and posterior neuropore closure (PubMed:14608380, PubMed:20654612).  Also required for proper development of the oral periderm (PubMed:24360809).  No genetic interaction with GRHL1, no functional cooperativity due to diverse target gene selectivity (PubMed:21081122).
What are the official names of this protein?
Grainyhead-like protein 3 homolog, Transcription factor CP2-like 4.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. Grainyhead subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUME_ECOLI
Sequence: MATLTEDDVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQDETPGFADDMTWDFISNVNSITRNAMLYDALKAMKFADFSVWSEARFSGMVKTALTLAVTTTLKELTP
What is the function of this protein?
In vitro catalyzes the addition of water to fumarate, forming malate.  Cannot catalyze the reverse reaction.  Cannot use the cis-isomer maleate as substrate.
What are the official names of this protein?
Fumarase E.
What is the protein family that this protein belongs to?
Belongs to the MtlR/FumE family.
Protein: MCRI1_CHICK
Sequence: MASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS
What is the function of this protein?
May play a role in the regulation of the epithelial-mesenchymal transition.
What are the official names of this protein?
Mapk-regulated corepressor-interacting protein 1, Protein FAM195B.
What is the protein family that this protein belongs to?
Belongs to the MCRIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, Stress granule.
Protein: EX7S_COLP3
Sequence: MAKKKLENLSFEESLNELDTIVQSLEQGELSLEESMTLFERGLNLSQLSQVKLQAAEQKVQILLDKNGTAKLTDFDSSAGES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ9_BOVIN
Sequence: MAATVAFSGVLRRAGWRLLQLRCLPVPRCRPALAPRAFRASAMQLRSLDQQKDQPPPSSSQQQSEAQGAEEPNPEALRSPPRYTDQGGEEEEDYESEEQLQHRILTAALEFVPTHGWTAEAIAEGAQSLGLSSAAASMFGDDGSELILHFVTQCNARLTHVLEEEQKLVQLGQAEKKKTDKFLRDAVETRLRMLIPYIQHWPRAFSILMLPHNIPPSLNLLTSMVDDMWHYAGDQSTDFNWYTRRAVLAGIYNTTELVMMQDSSPDFEDTWRFLENRISDAMNMGHTAKQVKSTGEALVQGLMGAAVTLKNLTGLNQRR
What is the function of this protein?
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.  Binds a phospholipid of at least 10 carbons in each acyl group.  May be required to present its bound-lipid to COQ7.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KAD_GEMAT
Sequence: MIIVLLGPPGAGKGTQGERLAARLDVPKIATGDVLRAAVKEGTPLGLEAKAAMDRGDLVPDAVIMGIMKEALAAPSAAKGAILDGVVRTTPQAAGLNDMLVALGRPLDAVLLFEVDEDELVRRLSGRTTCEACQRPFFGRQPGETCTEGGVSGTLVRRKDDEPEAIRKRMEVYREQTSPVIHWYEKSGANLVRVDAIGTLEEVEGRVLSALRIS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U19BA_XENLA
Sequence: MSGSKREAALTGQPKDERKKSGGGVINRLKARRVQGKESGTSDQSSVTPFREEELLGLNQLRPEHVLGLSRVTENYLCKPEDNIYGIDFTRFKIRDLETGTVLFEISKPCSEQEEEEEESTHLDASAGRFVRYQFTPAFLRLRKVGATVEFTVGDKPVKSFRMIERHYFRDHILKSFDFDFGFCIPNSRNTCEHMYEFPQLSEELIRQMTENPYETRSDSFYFVDNKLIMHNKADYAYNGGH
What is the function of this protein?
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Plays a key role in localization of proteins to the primary cilium membrane (By similarity).
What are the official names of this protein?
Protein unc-119 homolog B-A.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
Protein: TPIS_TAESO
Sequence: MTRKLFVGGNWKMNGSYSHINTFFDTLQKADTDPNADIVIGVPACYLKYAQDKAPKGIKIAAENCYKVGSGAFTGEISTEMIKDCGCEWVILGHSERRHIFGESNELIGEKVKHALDSGLNVIPCIGELLSEREAGKTNDVCFAQMDAIAKNVPSKEAWDKVVIAYEPVWAIGTGKTATPAQAQEVHKVVRDWIRKHVDAGIADKVRILYGGSVTASNAKDLGTQPDVDGFLVGGASLKPDFITIINARR
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_FRATN
Sequence: MAKVSKRMKEISAKINAEKKYPVSEAFDLLREVSSVKFVESVDVSVALGVDPRKSDQVVRGASVLPNGTGKTVRVAVFAKGPAADAAKEAGAEVVGMEDLADEVKKGNMDFDVVIASPDSMRVVGQLGQILGPKGLMPNPKVGTVTMDVAKAVRDAKAGQVRYRVDKAGIIHTTIGKVNFTSDALKQNLEQLLTDLKKAKPAVSKGIYLKKVSVSSTMGPGINVDFSDLNI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CX6BL_ARATH
Sequence: MSSAQMDPHDKMRSRDISKVARGQQAPRPAHTPGTVSPPPENEATFRAKRGDSGRETDAAVEERFPVTNETRHCFNRFMQYHKCIEKNGRDANDCNNLRDYVRSICPEELVSKIWLKSGRNKESQGHYQRQYED
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.  This protein may be one of the heme-binding subunits of the oxidase (By similarity).
What are the official names of this protein?
Putative cytochrome c oxidase subunit 6b-like.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B (TC 3.D.4.8) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SUCC_PECCP
Sequence: MNLHEYQAKQLFARYGLPAPTGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVSNKEDIRAFAENWLGKKLVTYQTDAQGQPVHQILVEAATDIDKELYLGAVVDRGTRRVVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQPYQGRELAFKLGLSGKQVAQFTKIFMGLATLFLERDLALVEINPLVITKQGDLVCLDGKLGADGNALFRQPELREMRDPSQEDSREAHAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGSPANFLDVGGGATKERVTEAFKIILSDDKVKAVFVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAATSLTGAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CS025_MOUSE
Sequence: MNSKAKKRVVLPTRPAPPTVEQILEDVRGAPAQDPVFTALAPEDPPDPSPRAEDSEIQQEQIYQQSRAYVAMNERLRQAGEALRQKFDGLRQAGQRLEQDISQVTSATS
What are the official names of this protein?
UPF0449 protein C19orf25 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0449 family.
Protein: DEKP1_ARATH
Sequence: MATETLELKTPQLADTVAVTEKDTETKKKDEVEKDEAMEEKGEEIDGEKVKSPVTPVSERPIRERKRTGRYVIDTPPRSSGNKPLSITQGRGTRLKEIPNVAYKLSKRKPDDNLFLLHTILYGKKAKAQMLKKNIGQFSGFVWSEQEEEKQRAKAKEKLDKCIKEKLIDFCDVLDIPVNKSTVKKEELAVRVLEFLVCPKATRDILLADSEKETKKRKKSTSKNVTSGESSHVPAKRRRQAKKQEQPTETEGNGESDVGSEGTNDSNGEDDVAPEEENNKSEDTETEDEKDKAKEKTKSTDKKRLSKRTKKEKPAAEEEKSIKGSAKSSRKSFRQVDKSTTSSSKKQKVDKDDSSKEKGKTQTSKPQAKGSKDQGQSRKKGKKEPTRKELHVVVTKILKEVDFNTATLSDILRKLGSHFGIDLMHRKAEVKDIITDAINEMSDDDDEKEEDTEDEGEKEGKD
What is the function of this protein?
Chromatin-associated protein which contributes to the modulation of chromatin structure (such as super-helical structure of DNA) and function (By similarity).  Binds to chromatin of protein-coding genes throughout the genome to regulate nucleosome occupancy and chromatin accessibility, and to modulate the expression of target genes (By similarity).
What are the official names of this protein?
DEK domain-containing chromatin-associated protein 1, At-DEK1, AtDEK-1, Protein DEK 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Associates with chromatin (By similarity). Enriched in regions where chromatin is decondensed or sparse in the interphase nuclei (By similarity).
Protein: RIBB_BUCAT
Sequence: MNQTLLSKFGKPIERIKNAILALKSGQGVIILDDEERENEGDLVFACENMTVEQMALSIRYGSGIVCLCITESKRKQLNLPMMVKKNTSAYRTGFTVTIEASKGISTGVSAKDRLTTIKTAIADDAKPSDLNRPGHVFPLRAHKGGVLSRPGHTEAAIEIVSLAGFKPAGVICELTNKDGTMARTPEIIKFSENKKMQVLTIQDLIFYIKNINHL
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RF2_BUCBP
Sequence: MFKNNNIINDRITNLVSQINKLKRRLDYDIKKNRLLEINMELKLPETWKHPSLIKKINKEKNQLISVVTQITKIDNDVQELIDILNLENSNNINSILDNVLYEFKNIEKSIHELEKCSMFLGKYDYLSCYVDIQSGSGGVEAQDWASMLLRMYVRWAESKKFKIDIIEQTYGEVVGIKSATIEVLGKYAFGWFRTETGIHRLVRKSPFNAHHRRHTSFSSVYVYPILDDAINVDINTRDLKIDVYRASGAGGQHVNKTESAVRIRHLPTGIVVQCQNDRSQHKNKDQAMKQLKAKLYEQLINEKKCQQKILENNKLNIGWGHQIRSYTLDNSRIKDLRTGVESKNIQSVLDGGLDLFVECSLRNGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA_ECOLI
Sequence: MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRARHALRENVSFYANASEALAAGFRPCKRCQPEKANAQQHRLDKITHACRLLEQETPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFPDSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDDDATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVWQALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGYRWGVSRKAQLLRREAENEER
What is the function of this protein?
The methylation of Ada by methylphosphotriesters in DNA leads to its activation as a transcriptional regulator that activates the transcription of its own gene, ada, and other alkylation resistance genes, alkA, alkB and aidB.
What are the official names of this protein?
Bifunctional transcriptional activator/DNA repair enzyme Ada, Regulatory protein of adaptive response.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MGMT family.
Protein: P30_ASFK5
Sequence: MKMEVIFKTDLRASSQVVFHAGSLYTWFSVEIINSGRIVTTAIKTLLSTVKYDIVRNARIYAGQGYTEQQAQEEWNMILHVLFEEETVSTSSTSLESNHETNGHKADGHEINECTSSFETLFEQEPSSETLKDTKLYALAQKAVQHIEQYGKAPDFNKVIRAHNYIQTIYGSPLKEEEKEEVRLMVIKLLKKK
What is the function of this protein?
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection (By similarity).  Necessary for virus internalization (By similarity).
What are the official names of this protein?
Phosphoprotein p30, p30, Phosphoprotein p32, p32.
What is the protein family that this protein belongs to?
Belongs to the asfivirus phosphoprotein p30 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion.