PharMolix/UniProtQA huggingface dataset:
Protein: PIMT_XANOR
Sequence: MTPRLRLQPESVGIGMTSQRVRDRLVERLREAGIHDEATLNAMQTVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVTPTKVLEVGTGSGYQGAILAALGLEVYTVERIGDLLRQARKRFRHLGMNVRSKHDDGRIGWHEHGPYDAIVVTAAAPALVDALVDQLAVGGRLVAPVGGASSQSLVQLTRGADGTIEQQVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMA_SALSV
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGNTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFSTEELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKLSGVQVSGNLAGHSAEIEKLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSQPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYSVGINGTKNDYQTYSELSVTNPYFTVDGVSLGGRIFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYNTLRAGLGYVHNSLSNMEPQVAMWRYLASMGQYPSTNDQDNSFSTDDFTFNYGWTYNKLDRGYFPTEGTRINLTGKVTIPGSDNEYYKATLDTATYVPIDNDHKWVILGRTRFGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYYPYNPKNYDADEDYDCATQDGAKDMCKSDDAVGGNAMAVASLEFITPTPFISEKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HOLE_SHIFL
Sequence: MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSWFRERLIAHRLASVNLSRLPYEPKLK
What is the function of this protein?
The exact function of the theta subunit is unknown.
What are the official names of this protein?
DNA polymerase III subunit theta.
Protein: RECF_BIFAA
Sequence: MHISRLALDHYRSWDHCVLDFEPGINILQGSNGLGKTNIVEAVEVLSTGSSHRTSSSLPLVEKGHPSATVRANVEDAGEQRTYEITIAARGANRARVDGGKSQYMRDIVGWVPSVSFTPEDQRLVSGDPATRRNFLNQAASLLLPRYAQSLQQFTHVAKQRAALLKQLSDGSGIDPEYGRQAVLSGLEVWTGQFIALGVQLTKDRNDVIGLLREPFTRIYASLAGEEEQADLVYEPSFDEVLLFDEPAAEISRHFQRIYPGEVARGQNLIGPQRDDLTLRLNDMPAREFASNGEMWTMALALKMALYEVVSAQRDVKPIVILDDVFAQLDESRRGQILDFARRQDQVLITVAAASDIPQGEAHVIDVAALRAQSQETDGDIAAMAAMLAAGRGAQSQGIEAES
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSHA_BACCR
Sequence: MTTFRELGLSDSLLQSVESMGFEEATPIQAETIPHALQGKDIIGQAQTGTGKTAAFGLPLLDKVDTHKESVQGIVIAPTRELAIQVGEELYKIGKHKRVRILPIYGGQDINRQIRALKKHPHIIVGTPGRILDHINRKTLRLQNVETVVLDEADEMLNMGFIEDIEAILTDVPETHQTLLFSATMPDPIRRIAERFMTEPQHIKVKAKEVTMPNIQQFYLEVQEKKKFDVLTRLLDIQSPELAIVFGRTKRRVDELSEALNLRGYAAEGIHGDLTQAKRMSVLRKFKEGSIEVLVATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKKGIAMLFVTPRESGQLKNIERTTKRKMDRMDAPTLDEALEGQQRLIAEKLQSTIENENLAYYKRIAEEMLEENDSVTVVAAALKMMTKEPDTTPIALTSEPPVVSRGGGSKKRGGNGGGYRDGNRNRSRDGRGGGDGRNRDRNRDGRNRDGNRDRNRDGNRDRNRDGGSRGRRGEGQGRPGSSNGRGERKHHSRPQA
What is the function of this protein?
DEAD-box RNA helicase possibly involved in RNA degradation.  May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.  Unwinds dsRNA in both 5'- and 3'-directions and shows RNA-dependent ATPase activity (By similarity).  Probably has a somewhat redundant function with cshB, as cshA can partially complement the growth effects of a cshB deletion.  Plays a role in adaptation to cold, oxididant and pH stress.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_BURP6
Sequence: MAIIPDKQDSSVLERKEQKLKPPSMYKVVLLNDDFTPMEFVVMVVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PPE36_MYCTO
Sequence: MPNFWALPPEINSTRIYLGPGSGPILAAAQGWNALASELEKTKVGLQSALDTLLESYRGQSSQALIQQTLPYVQWLTTTAEHAHKTAIQLTAAANAYEQARAAMVPPAMVRANRVQTTVLKAINWFGQFSTRIADKEADYEQMWFQDALVMENYWEAVQEAIQSTSHFEDPPEMADDYDEAWMLNTVFDYHNENAKEEVIHLVPDVNKERGPIELVTKVDKEGTIRLVYDGEPTFSYKEHPKF
What are the official names of this protein?
Uncharacterized PPE family protein PPE36.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GLO2_PARMW
Sequence: MQSSLHALPVLQDNVLWIWVRGDEAAVVDPAVAEPVIDWLQQRQLQLSAVLQTHHHADHIGGTPGLLERWPDAAVVAAGADRSRIPFQTISVSDGDQVTVLGRSLQVLDVAAHTSAHIAFVIPEQEDPDLGPVVFCGDTLFSGGCGRLFEGTPADMHRALRRLSELPESTKVCCAHEYTEGNLLWAIQQQPQDAAIRQRYDAVVDLRRRGELSLPSSIGEERRSNLFMRAASAEELGRLRRHKDHWRAA
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DMDA_RUEPO
Sequence: MASIFPSRRVRRTPFSAGVEAAGVKGYTVYNHMLLPTVFDSLQADCAHLKEHVQVWDVACERQVSIQGPDALRLMKLISPRDMDRMADDQCYYVPTVDHRGGMLNDPVAVKLAADHYWLSLADGDLLQFGLGIAIARGFDVEIVEPDVSPLAVQGPRADDLMARVFGEAVRDIRFFRYKRLAFQGVELVVARSGWSKQGGFEIYVEGSELGMPLWNALFAAGADLNVRAGCPNNIERVESGLLSYGNDMTRENTPYECGLGKFCNSPEDYIGKAALAEQAKNGPARQIRALVIGGEIPPCQDAWPLLADGRQVGQVGSAIHSPEFGVNVAIGMVDRSHWAPGTGMEVETPDGMRPVTVREGFWR
What is the function of this protein?
Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating demethylation of dimethylsulfonioproprionate (DMSP) to methyl-mercaptopropionate (MMPA).  The intracellular concentration of DMSP is estimated to be 70 mM.
What are the official names of this protein?
Dimethylsulfonioproprionate demethylase DmdA.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. DmdA subfamily.
Protein: UNG_AZOVD
Sequence: MGRVEDRVRLEASWKEALHDEFEKPYMQELSDFLRREKAAGKEIYPPGSLIFNALDSTPLDQVKVVIIGQDPYHGPGQAHGLCFSVQPGVPVPPSLQNIFKELKRDLNIDIPKHGHLQRWAEQGVLLLNTSLTVERGNAGSHAGMGWQRFTDRVIEVVSQRREHVVFMLWGSHAQSKRRLIDSSKHLVLCSAHPSPLSAHRGFIGNGHFSRANQFLEQHGLTPIDWHLPEEP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUPH_ECOLI
Sequence: MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQLNFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPLVIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGNDAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS
What is the function of this protein?
Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate.  Has a wide substrate specificity catalyzing the hydrolysis of ribose-5-phosphate, glucose-6-phosphate, fructose-1-phosphate, acetyl-phosphate, glycerol-1-phosphate, glycerol-2-phosphate, 2-deoxy-glucose-6-phosphate, mannose-6-phosphate and fructose-6-phosphate.  Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor.
What are the official names of this protein?
Sugar phosphatase YbiV.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily.
Protein: PTK7_DROME
Sequence: MTARMISICGLVMALMMASVLASSSRFQRVPQSQSVVENESVKFECESTDSYSELHYDWLHNGHRIAYDKRVHQIGSNLHIEAVRRTEDVGNYVCIATNLASGAREASPPAKLSVIYLESASVQLLGSNRNELLLKCHVEGASGDLEPLEIEWYRNSEKLSTWKNVQLDQHRLIIRQPGSEDDGLYRCTASNAAGRVMSKQGYVYQSSVKCLPRLPRRKNEKMMESWDKQTFLCRGKRGGAAGLEALPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQVELGGSAPIPGHSFDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEAHAPINSSPGILEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLPDHVEVDANGTLIFRNVNSEHRGNYTCLATNSQGQINATVAINVVVTPKFSVPPVGPIETSEQGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGNSAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPDVAGNGKGSEQEPCLSKQHNGHSKSRSKSSGDAQKSDDTACSQQSRASKKSAHIYEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNSENGSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQDQHNQSGLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCWVSNPKERPSFSQLGAALSKAMQSAEK
What is the function of this protein?
Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system.  Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage.  Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons.
What are the official names of this protein?
Tyrosine-protein kinase-like otk, Gp160-Dtrk, Dtrk, Off-track, Tyrosine-protein kinase-like 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TLP13_PHONI
Sequence: QKKDKKDRFYGLM
What are the official names of this protein?
Tachykinin-like peptide-XIII, P.nigriventer tachykinin peptides XIII, PnTkP-XIII, U29-ctenitoxin-Pn1m, U29-CNTX-Pn1m.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BFRB_MYCTU
Sequence: MTEYEGPKTKFHALMQEQIHNEFTAAQQYVAIAVYFDSEDLPQLAKHFYSQAVEERNHAMMLVQHLLDRDLRVEIPGVDTVRNQFDRPREALALALDQERTVTDQVGRLTAVARDEGDFLGEQFMQWFLQEQIEEVALMATLVRVADRAGANLFELENFVAREVDVAPAASGAPHAAGGRL
What is the function of this protein?
Possible cargo protein of a type 1 encapsulin nanocompartment involved in protection against oxidative stress (Probable).  Iron-storage protein that displays ferroxidase activity, catalyzing the oxidation of Fe(2+) ions into Fe(3+) ions, that can then be deposited as a ferric-oxide mineral core within the central cavity of the protein complex (PubMed:21494619, PubMed:24855650).  Retains ferroxidase activity inside the encapsulin nanocompartment with a slight decrease in rate.  It is not known if this protein is normally found in the encapsulin nanocompartment (PubMed:24855650).
What are the official names of this protein?
Bacterioferritin BfrB, Non-heme ferritin Ftn, Nox19.
What is the protein family that this protein belongs to?
Belongs to the ferritin-like superfamily. Prokaryotic family.
What are the subcellular locations of this protein?
Encapsulin nanocompartment. Note=Forms an approximately 12 nm shell inside the encapsulin nanocompartment, suggesting the latter encapsulates the entire 24-subunit homooligomer.
Protein: LHX4_HUMAN
Sequence: MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF
What is the function of this protein?
May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.  Binds preferentially to methylated DNA (PubMed:28473536).
What are the official names of this protein?
LIM/homeobox protein Lhx4, LIM homeobox protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBF_DAUCA
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CILP1_HUMAN
Sequence: MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKKPITLEAMETNIIPLGEVVGEDPMAELEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMFSVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQRRNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINLEPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSPKFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRVDRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQSPAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN
What is the function of this protein?
Probably plays a role in cartilage scaffolding.  May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions.  Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation.  May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1.  Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
What are the official names of this protein?
Cartilage intermediate layer protein 1, CILP-1, Cartilage intermediate-layer protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL34_KOCRD
Sequence: MPKRTFQPNNRRRARKHGFRARMRTRAGRAIIGARRSKGRASLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: IPYR_HAEDU
Sequence: MGLENVPAGKALPDDIYVVIEIPANSDPIKYEVDKESGSLFVDRFMSTAMFYPANYGYVNHTLSSDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGGDAKVVAVPHTKLTKEYDHIKDVNDLPALLKAQIQHFFESYKALEVGKWVKVEGWGDVNEARQEILDSFERAKK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA1A_CONOB
Sequence: YCCHPACGPNFSC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin inhibits fetal and adult muscle-type nAChR (IC(50)=52. 1 nM towards alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND, and IC(50)=102. 8 nM towards alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE).  Shows potent activity on the synthetic AChR alpha-1-beta-1-delta/CHRNA1-CHRNB1-CHRND (IC(50)=16. 9 nM).
What are the official names of this protein?
Alpha-conotoxin OI, Alpha-conotoxin OIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
Protein: FCP3C_DROME
Sequence: MDGAKAEVFSVSVDTKMGAFKNSLLLLTLLLAIHLEASKIVYKKPLYGNSNIIKDKRIKTKPVKLETSTMSSTGVASSSTTAEEDWPTAVEFVIMTTPASELEASTETIGNNGTTETTVGEAPIIGSSEGSTRSMEPTTASPLMSTNPSSSSSLVSTIPLPPTAGLPVQDNQPVPCTCGVFLSSQIPNGLPTKPLIHQELDHMFPCNAIGRKQCQTKCLETIVQHLPNSANIVCSALGHDCHKERAYLFIKNCHNQWVNTNLQAGREYCCRSGVPYRCPLMG
What are the official names of this protein?
Follicle cell protein 3C-1.
Protein: REX1B_BOVIN
Sequence: MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMKVIKTMEAISEVLQDLRFDAESAE
What are the official names of this protein?
Required for excision 1-B domain-containing protein.
Protein: MT1_CANLF
Sequence: MDPDCSCSTGGSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1, MT-1, Metallothionein-I, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: CECB_HELVI
Sequence: KWKVFKKIEKVGRNIRDGIVKAGPAIAVLGQAN
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.  Has also activity against fungi.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YEJB_ECOLI
Sequence: MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEFGNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVYNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWYQKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRIDFEGR
What is the function of this protein?
Probably part of a binding-protein-dependent transport system.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Inner membrane ABC transporter permease protein YejB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECR_RICRO
Sequence: MNETNYNDIDQLIYLFSKLPGLGIRSARRIALYLLQDKDVRLKSLINNLVEIDKKIVKCEICGNMDTENICRICSSEYRDKSIIAIVETVAELWAMERSGNFKGLYHVLGHNLSAASRQNPSILRLPELLTRCFAENIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDEGTVSAAINLRQPFE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: Y309_STRR6
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPIWNLPLHHPVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYASPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMNDLGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKSADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEELGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK
What are the official names of this protein?
UPF0371 protein spr0309.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: DNAA_ACHLA
Sequence: MSPNSTLWQTILQDLEKLYNEETYNELFLPVTSTFKDQNGLLTMVVANEFLKNRINKLYIAKINELATKYSSTPVRLKFVSQEEVIEEPVADRKLTIDYRQGNLNSTYTFDSFVVGKSNMFAFRMAMKVADHPGAVANPFYIFGDVGLGKTHLMQAIGNYILDNDVEKRILYVKADNFIEDFVSLLSRNKNKTEEFNAKYKDIDVILVDDIQIMANASKTQMEFFKLFDYLYLNNKQIVITSDKPASQLTNIMPRLTTRFEAGLSVDIQIPELEHRISILKRKTATLDANLEVSEDILTFIASQFAANIREMEGALIRLISYAQTFNLEITMNVVEEALGAVLKTKKKTNDLNENNYDKIQSIVADYFQVSLPDLIGKKRHAKFTLPRHIAMYLIKLKYNIPYKTIGSLFNDRDHSTVLSACEKVERDMRMDSNLKFAVDSIVKK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1414_CARHZ
Sequence: MNRRELGQKWEELAEQYLRKKGYKILTRNYQIRGGEIDIVAQDGEFLVFIEVRFRSDISFGTPSETVNEKKKASLKKAIKVYIHENFLYHLQPRVDFIGIEQKDNRFFVNHYQNVLDF
What are the official names of this protein?
UPF0102 protein CHY_1414.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HOA2_PSEP1
Sequence: MFDTRKKIYVSDVTLRDGMHAVRHQYSLADAERIARALDEAGVDSIEVAHGDGLQGSSFNYGFGAHTDLEWIERVAATVRRAKIATLLLPGIGTVHDLKNANAAGASVVRVATHCTEADISQQHIEYARKLGMDTVGFLMMSHMTTPTALAVEAKKMESYGAQCIYVVDSGGAMNMYDIADRFKALKDVLDPSTQTGMHAHHNLSLGVANSIVALEYGCDRIDASLTGMGAGAGNAPLEVFIAAVDRMGLKHGCDVRKLIDAAEEIVRPLQERPVRVDRETLALGYAGVYSSFLRHTEAAAHKYGLDAFEILVELGRRRMVGGQEDMIVDVALDMMSRKPQGTMRDVISH
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of p-cumate.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.