PharMolix/UniProtQA huggingface dataset:
Protein: URE1_HELP2
Sequence: MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKVSLAQLFSIF
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC1_ASPNC
Sequence: MSAGGEHLKDEGTRRQVVLAGGIAGLVSRFCVAPLDVVKIRLQLQIHSLSDPISHRDVTGPIYKGTLSTMRDIIRQEGITGLWKGNIPAELMYVCYGVIQFSAYRTTTQALAQLDTYRLPPSAESFVAGATAGGLATASTYPLDLLRTRFAAQGTDRVYTSLMSSVRDIARNEGYAGFFRGCSAAVGQIVPYMGLFFATYEALRPPLAQYQDLPFGSGDAAAGVIASVSSKTVMFPLDLIRKRLQVQGPTRQLYIHRNIPEYQGVFNTMKLILRTQGIRGLYRGLTVSLFKAAPASAVTMWTYETSLRLLQDMEVATSKED
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPRT_VIBA3
Sequence: MSYTPQQHRVNKKLGECLAIANQHFSREFPCPTVTYKLRGKAAGKAYLQLNEIKLNQVLFSENEDAFINEVVPHELAHLITHQVFGRVRPHGNEWKYVMEKVFNVPARTTHSLEITSVQGKTFEYRCDCTTYPLSIRRHNKVIRNQSTYRCQQCQQTLAFTGLQLS
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_HELPG
Sequence: MNTKEPHKRLVQGKVISKFAEKSAVILVERKVVHEKYRKIVKKFKKYTIHDENNQVKVGDFVSAIECRPLSKTKSFTLKEILVVGV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: D13_VARV
Sequence: MNNTIINSLIGGDDSIKRSNVFAVDSQIPTLYMPQYISLSGVMTNNGPDNQTIASFEIRDQYITALNHLVLSLELPEVKGMGRFGYVPYVGYKCINHVSVSSCNGVIWEIEGEELYNNCINNTIALKHSGYSSELNDISIGLTPNDTIKEPSTVYVYIKTPFDVEDTFSSLKLSDSKITVTVTFNPVSDIVIRDSSFDFETFNKEFVYVPELSFIGYMVKNVQIKPSFIEKPRRVIGQINQPTATVTEVHAATSLSVYTKPYYGNTDNKFISYPGYSQDEKDYIDAYVSRLLDDLVIVSDGPPTGYPESAEIVEVPEDGIVSIQDADVYVKIDNVPDNMSVYLHTNLLMFGTRKNSFIYNISKKFSAITGTYSDATKRTVFAHISHSINIIDTSIPVSLWTSQRNVYNGDNRSAESKAKDLFINDPFIKGIDFKNKTDIISRLEVRFGNDVLYSENGPISRIYNELLTKSNNGTRTLTFNFTPKIFFRPTTITANVSRGKDKLSVRVVYSTMDVNHPIYYVQKQLVVVCNDLYKVSYDQGVSITKIMGDNN
What is the function of this protein?
Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV).  This association occurs concomitantly with viral membrane formation.  Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis.  In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm.  This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus (By similarity).
What are the official names of this protein?
Scaffold protein D13, 62 kDa protein, Rifampicin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein D13 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Associates transitorily with crescent and IV membranes.
Protein: EPP_BOMMO
Sequence: MANLPPRKVTSASKSKQDVSPLQILLQMGFRRQRALKALAATGNRSVQLASDWLLTHVSDSNIDADDPREYIFYASPTGPLLSQLLEFWDKSKSTCGWNGAHNFLPHITLVSFFKAPDDTSLNLAKAVRQVVENVGDPPKCTLKLEPYVSHNFMGLFISEEHAEYLKKIAVQYVKQVSSVSSINLEAHVKSLHITLAYHFEESSYEDLKTLVEEMQPVEHSSWELRLYSRDPRFANHQVYKVTQGYSPQASDELELVLGDYIYIEEKEFDISPDGWVHGTSWLTGLNGYLPAVYTRRTAETDAWTLLKAVSLGNNCSDCKSESGSNTDSEMAGTYPHEDAADLAYKKSEETYQEWDKYWSEVMNSRSDSILTITQGLPMNWELSKAAEEMKNNITNGTSKSRRWVFALRHGERVDLTYGPWVPHCFENDTYVRKDLNLPLKLAHRAGGKGGYVKDTPLTRLGWFQAQLVGEGMRMAGVSIKHVYASPALRCVETAQGFLDGLRADPSVKIKVEPGLFEFKNWHMPKGIDFMTPIELCKAGLNVDMTYKPYVEMDASAETMDEFFKRGEVAMQAAVNDTEKDGGNVIFIGHAITLDQMVGALHRLRDDMEDVQPYEIGRNLLKVPYCALGAMRGKPWDVVSPPCPPSINSSSGRFDWRILIK
What is the function of this protein?
Steroid phosphatase which catalyzes the conversion of inactive phosphorylated ecdysteroids into their active forms (PubMed:12721294, PubMed:15738639, PubMed:18937503).  Shows high activity towards ecdysone 22-phosphate (E22P) (PubMed:12721294).  Has lower activity towards other ecdysteriod phosphates including 20-hydroxyecdysone 22-phosphate (20E22P) and 2-deoxyecdysone 22-phosphate (2dE22P) (PubMed:12721294).  Also has protein tyrosine phosphatase activity (PubMed:18937503).
What are the official names of this protein?
Ecdysteroid-phosphate phosphatase, EPPase.
Protein: ZNUC_AGRFC
Sequence: MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIGVAKPSEGKVSRKAGLRVGYVPQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAHLANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVDFSGEIALYDLIKNIRNSNDCGILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHHDHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TLN2_MOUSE
Sequence: MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKRSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATSDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAISNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGEASKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIMLCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFASIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAVHTAPEPKGTFVDYQTTVVKYSKAIAVTAQEMIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAENGETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLIACKQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAV
What is the function of this protein?
As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion.  Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
What are the official names of this protein?
Talin-2.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Synapse. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Focal adhesion plaques and synapses.
Protein: PSBN_SOLLC
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LIPA_LEGPA
Sequence: MGKLIDIPIVVESGQKYKTSQGVTAIKDGIKSSGQDHERLPKPKWLRIVNHTTPAYSQVKEQVQKHRLATVCEEAKCPNISECWSHGTATIMLMGAVCTRACRFCSVDTGNPHGWLDAEEPENTAETVALMNLDYVVLTSVNRDDLPDGGANHYAKTIRAIKKRSPRTKVEALTPDFQGSERDVAVLLDSGVDVFAQNVETVERLTHPVRDNRAGYQQTLNVLAFAKKYRPDVLTKTSLMLGLGETDEEIIQTMDDLRTHHVDILTLGQYLQPTKNHLPIARYVTPETFSELRQIGLKKGFFEVASGPLVRSSYRADRVFKRDNLGLDV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSEC_CAMJJ
Sequence: MITYSHQNIDQSDIDALTKALKDEILTGGKKVDEFEEALCEYIGVKHACVLNSATSALHLAYTALGIKEKIVLTTPLTFAATANAALIAGAKVEFIDIKNDGNIDEKKLEARLVKNSTDIGAISVVDFGGNSVEMDEISNLAKKYNIPLIDDASHALGSEYKGKKVGSMADLSIFSFHPVKPITTFEGGAVVSNNKELISKIKLLRSHGIVKKRLWDSDMIELGYNYRLSDVACALGINQLKKLDHNLEKREEITSFYDKEFEKNHYFSTIKIKDYKKSSRHLYPILLFPEFYCQKEELFESLLHAGIGVQVHYKPTYEFSFYKKLLGEIRLQNADNFYKAELSIPCHQEMNLKDAKFVKDTLFSILEKVKKGYCG
What is the function of this protein?
Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.
What are the official names of this protein?
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase, Pseudaminic acid biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: YCF37_NEOYE
Sequence: MILALPIFYLSILTIFLLILNWLIFQQLKTILLLESQFKYFVDKSQNRKLEPDESFAFAKVCVAKKYFSKAIIEGQLALKNYRDLNILDNNIVIANLYNMLGFIYFEAGQTSFAKNFYEQALQINPNYVVALNNLAKIYEEVKDLKKAESLYDKVLTLNLNNKTANRRKDFIAKTKNI
What are the official names of this protein?
Uncharacterized protein ycf37.
What is the protein family that this protein belongs to?
Belongs to the ycf37 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYC_BLOFL
Sequence: MLKIFNTLTKKKEIFKSIKCGEIKIYVCGITVYDLCHLGHARTFVIFDTILRYLKHYGYQVKYVRNITDIDDKIIQRAIKNNETTDHLASRMIQEMYLDLDILNILRPNYEPKVTDHIELIINFIRLLIERNHAYVTSDGNVMFSIQTVYNYGVLSCHKKNQTFTQRNIRNKMIKKDPVDFVLWKTAKSGEPYWISPWGKGRPGWHIECSAISHAFLGKHIDIHGGGSDLVFPHHENEIAQSTCAHHITVDSYVNTWIHTGMLTFNDEKMSKSLNNFFTIREIIQKYDPETIRYFLLSAHYRKPLRYSDNNIKNARLSLKHLYSALHGINFNPIVQLYDNNSEKYFISKFNNKMNNDFNFPEAYSILFEMAHALNIAKIKDHVRAKSLAAHLKYLANILGILYQDPEIYLGYNTCIKNNKQSLTVEKIRELIYMRENARKNKEWQLSDKIRKRLTEIGIILEDKPTGKTIWRYN
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZITB_PECAS
Sequence: MAHNHSHTESGNSKRLLAAFIITATFMVAEVIGGLLSGSLALLADAGHMLTDAAALFVALVAVRFAQRKPNARHTFGYLRLTTLAAFVNALTLILITAFIFWEAIQRFYDPQPVAGVPMLLVAIAGLLANIVAFWLLHHGSEEKNINVRAAALHVLGDLLGSVGAIAAAIIILYTNWTPIDPILSILVSCLVLRSAWALLKESIHELLEGTPSQLSVEALQKDVTLNIPEVRNIHHVHLWQVGEKPMMTLHAQVVPPHDHDALLRRIQEYLLKHYQIEHATIQMEYQRCDDDHCSFHQENHHLAIHDGEKHDAEGHHHKH
What is the function of this protein?
Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc.  It may contribute to zinc homeostasis at low concentrations of zinc.
What are the official names of this protein?
Zinc transporter ZitB.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RCK2_YEAST
Sequence: MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVPAIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKELIGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE
What is the function of this protein?
Serine/threonine-protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.
What are the official names of this protein?
Serine/threonine-protein kinase RCK2, CAM kinase-like protein kinase CLK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELP3_CAEEL
Sequence: MDQKGSQRALLAQTINEIVKLLIEAHNQKKDVNLNRLKCIVAQKNGLSFQPKLVDIIAGVPSDYKDSLLPKLKAKPVRTASGIAVVAVMSKPHRCPHINFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPYLQTRGRLNQLMQLGHSVDKVEFIVMGGTFMSLPEDYRDFFIRNLHDALSGHTSASVEEAVAYSERSKMKCIGITIETRPDYCLPRHLNDMLLYGCTRLEIGVQSTYEDVARDTNRGHTVKSVCETFHMAKDTGYKVVIHMMPDLPNVGLERDKEQFLELFESPAFRPDGLKLYPTLVIRGTGLYELWKTGRYQSYPPSVLVDLIATILSLVPPWTRVYRVQRDIPMPLVSSGVEHGNLREHAMAKMKELGLKCRDVRTREVGIQEIHNKVRPEDVELIRRDYTANGGWETFISYEDPKQDILIGLLRLRKISDKAHRPELKGNVSVVRELHVYGSVVSVADRDPKKFQHQGYGSLLMEEAERIAREEHGSDKIAVISGVGTREYYRKLGYELDGPYMSKMLDSAAA
What is the function of this protein?
Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
What are the official names of this protein?
Elongator complex protein 3, tRNA uridine(34) acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
Protein: RNFH_SALCH
Sequence: MPDKLVVEVAYALPEKQYLQRVTLEEGATVEEAIRASGLLELRTDIDLAKNKVGIYSRPVKLTDTVQDGDRVEIYRPLIADPKALRRQRAEKSAGR
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: VATA_AERPE
Sequence: MAVKGSIVRISGPLVVAEGMSGAQMYEMVYVGEDRLIGEITRIRGDRAFIQVYESTSGLKPGEPVVGTGAPLSVELGPGLLGTIYDGVQRPLPIIAEKVAEVDPRRRMFVERGIQAPPLPRDRKFHFKPEPLKEGDKVEGGDALGRVPETSLIEHVVMVPPGIRGRLKWLASEGDYSVEDTIAVVERDGRDVEIRMHQRWPVRIPRPFKEKLEPQLPLITGVRIIDTFFPMAKGGTGAVPGGFGTGKTVTLHSLAQWSEARVVIYIGCGERGNEMTEVLERFPQYKDPWTGKPLMDRTVLIANTSNMPVAAREASIYVGITIAEYYRDMGYDVLLVADSTSRWAEALREIAGRLEEMPAEEGYPSYLASRLAEFYERAGRVKALGSPERSGSVTVVGAVSPPGGDFSEPVTSHTTRFIRVFWALDTKLAYSRHYPAINWLMSYSAYVDLVTQWWHENVDKRWREYRDEAMDILLRESELQEIVRLVGTEGLDEKDKMVLETARLIKDGFLKQNAFDPIDAFATPQKQFRLLKMIMDIHRKSLELIEKGVTTQQILQALGRLYIDIVKAKFTIPNDQLEKIDEIRDRALKALDELVSG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: NUSAP_BOVIN
Sequence: MIVPSLEELNSFKYSDLQNLAKSLGLRANLRADKLLRALKAHLKNEARKENENQDEIQTSASSCDEPEIQTSSQEQAEREPDDHVTKTRGRRKTVHRSPDSQANGNVQTEKKLPPVPNLQNHSEIKLCGPTKSQNQEKHENQVLRTAVEVPSLPNESQGDENTVSSGKHGIDGNEDPRVPSKRKKSLYTDGFSKPGKNKTASTTPNFKKLHEARFKEMESIDQYVERKKKHFEEHNSFNELKVLQRQPVTKGVPATPVPARGRLSVACTPGSQRRSQGRPHAGRSTLCVKGSAKRSALSAAKMNVRFSAATKDNEHKRSLTKTPARKSPHVTTSVNTPKGQAVLGTHKLKTTRGESVAVITPFKLTTEASQTPISHKKPVFDLKASLSRPLNYEPHKGKLKPWGQSKENNSLHEHVNRVSFHKKTYKQPRLQTREEQRKKHERERKEKKEKVLGVRRGLIIAERS
What is the function of this protein?
Microtubule-associated protein with the capacity to bundle and stabilize microtubules.  May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity).
What are the official names of this protein?
Nucleolar and spindle-associated protein 1, NuSAP.
What is the protein family that this protein belongs to?
Belongs to the NUSAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Chromosome. Note=Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase. Localizes to the mitotic spindle and to the chromosomes during anaphase and telophase then disappears from around the chromosomes during cytokinesis.
Protein: VILI5_ARATH
Sequence: MTFSMRDLDQALQGAGQKSGIEIWRIENFKPVTVPQESHGKFFTGDSYIVLKTTASRSGSLHHDIHYWLGKDSSQDEAGAVAVMTVELDSALGGRAVQYREVQGHETEKFLSYFKPCIIPQEGGVASGFNHVKPEEHQTRLYICKGKHVVRVKEVPFVRSTLNHEDVFILDTESKIFQFSGSKSSIQERAKALEVVQYIKDTYHDGKCDIAAVEDGRMMADAEAGEFWGLFGGFAPLPKKPAVNDDETAASDGIKLFSVEKGQTDAVEAECLTKELLDTNKCYILDCGLELFVWKGRSTSIDQRKSATEAAEEFFRSSEPPKSNLVSVMEGYETVMFRSKFDSWPASSTIAEPQQGRGKVAALLQRQGVNVQGLVKTSSSSSKDEPKPYIDGTGNLQVWRINCEEKILLEAAEQSKFYSGDCYILQYSYPGEDREEHLVGTWFGKQSVEEDRASAISLANKMVESMKFVPAQARINEGKEPIQFFVIMQSFITFKGGVSDAFKKYIAENDIPDTTYEAEGVALFRVQGSGPENMQAIQIEAASAGLNSSHCYILHGDSTVFTWCGNLTSSEDQELMERMLDLIKPNEPTKAQKEGSESEQFWELLGGKSEYPSQKIKRDGESDPHLFSCTYTNESLKATEIFNFTQDDLMTEDIFILDCHTEVFVWVGQQVDPKKKPQALDIGENFLKHDFLLENLASETPIYIVTEGNEPPFFTRFFTWDSSKSGMHGDSFQRKLAILTNKGKPLLDKPKRRVPAYSSRSTVPDKSQPRSRSMTFSPDRARVRGRSPAFNALAANFEKLNIRNQSTPPPMVSPMVRKLYPKSHAPDLSKIAPKSAIAARTALFEKPTPTSQEPPTSPSSSEATNQAEAPKSTSETNEEEAMSSINEDSKEEEAEEESSLPTFPYERLKTDSEDPVSDVDLTRREAYLTSVEFKEKFEMTKNEFYKLPKWKQNKLKMSVNLF
What is the function of this protein?
Major actin filament stabilizing factor and regulator of actin dynamics.  Binds actin and actin filament bundles in a Ca(2+)-insensitive manner, but caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner.  Required for the construction of actin collars in pollen tubes.  Acts synergistically with VLN2 (AC O81644) to regulate polarized pollen tube growth.
What are the official names of this protein?
Villin-5.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present in the apical and subapical regions of pollen tubes.
Protein: TIG_CHLCH
Sequence: MQKTITPLSPTEQELEIILSAEEFGPEYNKELDEAKRTVHIKGFRKGHAPMGLLKKLAGPSIEIAVAEKLGGKYFTDIITAENIKPANRAQIADFAFTDDTLTLKLVYEIHPEFELQDFSGYTFTKANYVVGDKEVEREIELILKSHGTMVTSDEPASEKDTVIGDALRFNDEGELDEASKVANHHFSMEYLPAENPFRIALLGKKAGDVVEVVNTPIKEDEEGEEATAEDAEAVKPTRFQVTVTEVKRLELPELDDELVKEISQERFDNVADFKADVRLQLEQHFTMKSDNDLLEAISGKMVEENPVPVPNSMVESFQDMLLENAKRQLSGNFPKGFDVTGFRASMRDNAEKHARWMLITQKVAEMNKLTVTDEDIVAFAEKEAGKNEALDIKQIIETYKSPDFHDYIADSIMKEKVYNAITEKVTVTEEETPVPEHRM
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: INVSB_XENLA
Sequence: MSNPPQGSSLASPIQAAAVTGDKTTLLRLIASSPQVIDQEDQLGRTPLMYSVLGDRRSCAEALLKHGAKVNRPDRSGRTALHLAAQTGNHRLLKLLLSRKADCTHRDLCDITALHLSTRHQDTQCLVLLLKYTPPGQVDAQDQRKQTALHWSAYYNRPQHVRLLVRHGSNIGIPDTEGKIPLHWAAGHKDPEAALTVRCLFEAAPTESLLNWQDYEGRTPLHLAVGDGNQEVVRLLTSYRGCNVAPYDNLFRTPLHWAALLGHTPIAHLLLERNNSPNIPSDSQGATPLHYAAQGNCPDTVRVLLSHPSVRDEADLEGRTALMWAAGKGSDEVVRTMLELNPKLEVNRTDKYGGTALHAASLSGQITTVRILLENRAQADAVDVMKHTPLFRACEMGHREVIATLIKGGAKVHLVDKDGRSPLHWAALGGNANVCQILIENNINPDAQDYEGRTPLQCAAYGGYIGCMEVLMENKADPNIQDKNGRTALHWSCNNGYLDAVKLLLGYNAFPNQMENTEERYTPLDYALLGGHQEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGHKVRRAFQERKNLLMKHEQLRKGAAAKKREGENRQKVKVGQTKGKQKDADSMERQNKSNEQIIKNEVVHEWQGEASGNAEDRKGKHREENLETNHLQHSKHMAKNQRITAQIQSSPSEHEHTNSIQIRTSPSGTSNTQSSPLGNEIPKNMYWDDNPSQKHTQTRRTSRHQMESPDVVVHRIEDLIQKESRRKSHREERKGSHRQRQSSDYRLHTSEKEASDSAIHREEEGKKKETKKGRRTVAVTPKIEACCKGGCGKLSQSEKVSLGIGIQGRVDCITSPEPCETPSRVCRERKTISAKTGQRPLTETHKPPGKACRSSSALKSSLPSHIKQTAIDSKCLDSTLSYIGFGEAIKPLFPMGILREGSFFSKWQNIDIELIPVQARLQLVEREKARKQLFQRKNHAATVIQKAWRTYWVRKSSCKTRHSRSQNNPPAMV
What is the function of this protein?
Required for normal renal development and establishment of left-right axis.  Probably acts as a molecular switch between different Wnt signaling pathways.  Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome.  This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling.  Plays a central role in convergent extension movements in gastrulating embryos, a processus regulated by Wnt signaling (By similarity).
What are the official names of this protein?
Inversin-B.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the cytoskeleton.
Protein: RNPH_METC4
Sequence: MRPSKRAADAMRDVTLERAVARYAEGSCLVTFGNTRVLCTASLEERGPPWLRGSGKGWVTAEYAMLPRATHERTRREVNSGKPSGRTQEIQRLIGRSLRAVTNLPALGERQITVDCDVIQADGGTRTASITGAWVALHDCFAWMRARSIISVDPLKDHVAAVSCGIYKGQPVLDLDYAEDSAAETDANFVVTGKGGIVEVQGTAELEPFTDEQFLELLRLAKGGVAGLVELQRKAIA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.