PharMolix/UniProtQA huggingface dataset:
Protein: RL5_ACIAC
Sequence: MARLQQHYREKIVPELTKQFGYTSPMEVPRLTKITLNMGVSEAVSDKKVMDNAVADLTKIAGQKPVVTKAKKAIAGFKIREGQAIGCMVTLRGVQMYEFLDRFVTVALPRVRDFRGISGRAFDGRGNYNIGVKEQIIFPEIEYDKVDALRGLNISITTTAKSDEEAKALLAGFRFPFKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYFB_SHEON
Sequence: MKFSESWLREWVNPAVSREALSHQITMAGLEVDGVDAVAAEFNGVVIGEVVECGLHPDADKLRVTKVSVGSSELIDIVCGAPNCRQGLKVAVAMVGAVLPGDFKIKKAKLRGMPSEGMLCSYSELGIDIDSDGIIELPLDAPLGTDLREYLKLDDAVIEVDLTANRADCLGMVGLAREVGVLNRQAVTEPQWQAVTPTTDAKVTINVKESAACPRYLGRVVKNVNVKAATPLWMQEKLRRSGIRSIDPIVDITNFVLVEFGQPMHAFDLAKLTGDIQVRLGNGEEKITLLDGSEVTIPSDTLVIADDARPLALAGVFGGEYSGVSDTTQDILLECAFFAPLAIMGKSRRLGLHTDSSHRFERGVDPEMQHKVIDRATRLVLDICGGEAGPVVEAKSDADLPKPAQILLRRSKLDKILGHYVPDSDVVEILERLGFSVVKGEGCWQVITATYRFDMAIEEDLIEEVARIYGYNNIPNVAPIASLRMSDHKETDLSLKRVRSLLVARGFQEAVTYSFVDPKLQNLVHPGEQAMVLPNPISSEMSAMRLSMFTGLLTAVGYNQSRQQGRVRLFETGLRFVPDINAESGVRQQAMLGCVITGPQNDEHWAMESKTVDFFDLKGDLEAIIGLTVSASEFSFRVATHSALHPGQCAEILRNDRVIGHIGAIHPSLEKPFGLNGKTIVFELELDALLHTSLPLAQAVSKFPANRRDIAVVVDESVSAGDVMKLIRKVGENQLVGINLFDVYLGKGVEPGKKSLAIALTLQDTTRTLEEKEIAETVESVVSALKTEFNASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_MYCTU
Sequence: MPKPADHRNHAAVSTSVLSALFLGAGAALLSACSSPQHASTVPGTTPSIWTGSPAPSGLSGHDEESPGAQSLTSTLTAPDGTKVATAKFEFANGYATVTIATTGVGKLTPGFHGLHIHQVGKCEPNSVAPTGGAPGNFLSAGGHYHVPGHTGTPASGDLASLQVRGDGSAMLVTTTDAFTMDDLLSGAKTAIIIHAGADNFANIPPERYVQVNGTPGPDETTLTTGDAGKRVACGVIGSG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.  May play a role in favoring mycobacterial survival in phagocytes (By similarity).
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL1_MARMS
Sequence: MAKLTKRARLIAEKVEATKLYSVEEAVALLSELSTVKFKESIDVSVNLGVDPRKSDQVVRGSTVLPHGAGKDVRVAVFAQGANAEAAKEAGADVVGFEDLAEQVKAGNLDFDVVIASPDAMRIVGQLGQVLGPRGLMPNPKVGTVTPDVATAVRNAKAGQARYRTDKNGIIHAAVGSIEFAADAIRGNLEALLTDLRRAKPASSKGVYLRKVTLSSTMGPGLQIDLGALNSTK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TF2B_RAT
Sequence: MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFDTPVDKLPQL
What is the function of this protein?
General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II).  Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA.  Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex.  Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle.  Associates with chromatin to core promoter-specific regions.  Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element.  Modulates transcription start site selection.  Exhibits also autoacetyltransferase activity that contributes to the activated transcription.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB, RNA polymerase II alpha initiation factor.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis. Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle.
Protein: SYH_BACTN
Sequence: MAAKPSIPKGTRDFSPVEMAKRNYIFNTIRDVYHLYGFQQIETPSMEMLSTLMGKYGDEGDKLLFKIQNSGDYFSGITDEELLSRNAVKLASKFCEKGLRYDLTVPFARYVVMHRDEITFPFKRYQIQPVWRADRPQKGRYREFYQCDADVVGSDSLLNEVELMQIVDTVFSRFNIRVCIKINNRKILSGIAEIIGEADKIVDITVAIDKLDKIGLENVNAELKEKGISDEAIAKLQPIILLSGTNTEKLATLKSVLAASETGMKGVEESEFILGTLETMGLKNEIELDLTLARGLNYYTGAIFEVKALDVQIGSITGGGRYDNLTGVFGMAGVSGVGISFGADRIFDVLNQLELYPKEAVNGTELMFVNFGDKEAAFSMSMLAKVRAAGIRAEIFPDAAKMKKQMSYANAKSVPFVAIVGENEMNEGKAMLKNMETGEQNLVSVEELIAALRN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_LEGPA
Sequence: MSTIQLEAQSRTDMGKGASRRLRRLENKVPAVIYGGSKKPMAIHFSHNKVIKALETESIYSSVFDITVDGKVEHVILKALQRHPYKPIVLHMDLQRVSSKDILVKLVPVHFINEEQSPGIKAGGIVQHTMTQVEIRCQAKDLPEFIEVDMSKVGMDDVVHLSDLKLPKGVQLTVDVADGSHDAPVVSIHAAKVSSTELEETPEVPASAVPTTDQGESAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TSYL1_BOVIN
Sequence: MSGRDGGERTPLLEAHSLTTSDCAAGAPDPSRCLKTEASQVMAETGEGYFEAVALPPPQLPEEESAPSTAPSDPGCAGTFQIRAGGDGGYVVPEARLEPAPPPTESLETASVSLATDDSLGNGCQPGEPQGLSREKPLETCGAEKLGSDLMAEAKAEEVKTEEGPVFSVAVDEEVVGKEGAKEEEGVEQGMEVEERPVGEEIEMVENRVVEEAGHRPLRMDLRMNPLEAIQLELDSVNAQADRAFQQLEHKFGRMRRHYLERRNYIIQNIPGFWVTAFRNHPQLSPMIRGQDAEMLRYITNLEVKELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRASGRVVSLSTPIIWRRGHEPQSFIRRNQEVVCNFFTWFSDHSLPESDRIAEIIKEDLWPNPLQYYLLREGVRRARRRPIREPVEIPRPFGFQSG
What are the official names of this protein?
Testis-specific Y-encoded-like protein 1, TSPY-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RPOZ_BACAA
Sequence: MLNPSIDSLLTKIDSKYTLVTVAAKRAREMQLANNCVVEKPVSHKCVGKALEEIDMEALSYVPSEDKVTE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: LEUC_PYRHO
Sequence: MTLVEEILDAKAGEVVIRNVDLVYAHDGTMPLIIEAFNKVFNSVKARAYVFFDHVYPAPTVKVANLQKEIREFARRHGIPVVEGKGISHQLVVEMGLAEKSRIVVGGDSHTPTLGALGVFAVGMGATDVAVVLGLGKTWLRVPESVAVIFEGKPSRTTMAADVMIRLITSLRNYDMNYKALEFFNVPFTADERLTLTNFSVEANAKTALIGEEYDGRNYIKEISFELSSLGPMVAKPFSPANGVEVEKVEGTKIDQVFIGSCTNGRFEHIKRAAEILKGEEVAVRTIIGPASVNVYKRMVREGIVDILLDAGATILPPGCGPCLGRHMGVLGDKEVVLSTTNRNFRGRMGSPTAEIYLASPLTAAVSALYGEITSPGGEV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: ASTE_ASPOR
Sequence: MTGNEQKFSLQGKVAIVTGAGSGIGRETALCLANAGANVVVAEANETTGKETAAKVSAQTGSRGLFILTDVSRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVGVAFCLKWELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVENGRHGIRVNALAPGGVATDLTMATMQELGLTEENEAARSSLFKRFAKPEEIAQSVLWLASDAASYVTGATIAVDSGLSLI
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599).  The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599).  Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599).  Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599).  The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599).  The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599).  Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
What are the official names of this protein?
Short chain dehydrogenase/reductase astE, Astellolide biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PHZG_BURL3
Sequence: MNTSRFESLTGSVDVLFPEYDDPPSEPITLLKRWLATADVARVREPKALALATATSDGRISSRVIAFSSIDDRGVIFCTHSTSRKGRELTETGWASGLLYWRETGQQIMISGQAVPLEESENDKLWFGRSVPMHAMSSASHQSDELVDREALRAHAAELLALGVALPRPPRFVGYRLEPHEMEFWAASSDRLHRRLRYERDGNDWKTTQLQP
What is the function of this protein?
Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control (PubMed:23897464).  Catalyzes several oxidations in the terminal steps of core phenazine biosynthesis.  It oxidizes both hexahydrophenazine-1,6-dicarboxylic acid (HHPDC) and tetrahydrophenazine-1-carboxylic acid (THPCA) and thereby contributes to the generation of both phenazine-1,6-dicarboxylic acid (PDC) and phenazine-1-carboxylic acid (PCA).  It synthesizes phenazines in their reduced form, which are the likely end products in vivo (PubMed:23897464).
What are the official names of this protein?
Dihydrophenazinedicarboxylate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PCDB3_PANTR
Sequence: MEAGGERFLRQRQVLLLFVFLGGSLAGSESRRYSVAEEKERGFLIANLAKDLGLRVEELAARGAQVVSKGNKQHFQLSHQTGDLLLNEKLDREELCGPTEPCILHFQILLQNPLQFVTNELRIIDVNDHSPVFFENEMHLKILESTLPGTVIPLGNAEDLDVGRNSLQNYTITPNSHFHVLTRSRRDGRKYPELVLDKALDREEQPELSLTLTALDGGSPPRSGTAQINIQVLDINDNAPEFAQPLYEVAVLENTPVYSVIVTVSASDLDTGSFGTISYAFFHASEEIRKTFQLNPITGDMQLVKYLNFEAINSYEVDIEAKDGGGLSGKSTVIVQVVDVNDNPPELTLSSVNSPIPENSGETVLAVFSVSDLDSGDNGRVMCSIENNLPFFLKPSVENFYTLVSEGALDRETRSEYNITITITDLGTPRLKTKYNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHKLAVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAERVSEANPSFRKSFEFS
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-3, PCDH-beta-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SED5_ASPFU
Sequence: MYPLDGSARPHPPGTTRLNSVEPDKQIGFTVLVRPQTGAPRLPDLAQWQAIPIAERQFLSTAGFERTYGSSEDDIVSVASFLEKAGMTIRSRHAGAGTVEVQAKTCQIHSVFAVQLLYYRGQLRPAARKRRDDKQPAEETYIGFEGCISLPAALHDKVIHIFGLDTRTFGASGGYSGDPPRAQRLIVAELAALYGFPAGVDASQQTIGIFSGEGNDDKGQSLSNYRPADVAAYFNNQTVGYNRAPTVVPVSLTVADQTYRNDPDHPTQELSQDIMTAATIAQGCTVNVYFSDLTEQGWLAFLTRVLFPQGEEKRPTIVSISWTMYDEQTYRDRLSFLFQRLAVVGTSVFAIAGDWGANNNIIDGQPHVGWPGSDPWVTCVGGTVVGNVRSSGAFTEHAWSDRDNPDSQFTIDGHLGVTGGGMSRVFATPPYQLSSGISAVTDCNGERWTGGRFIPDITGMVGFRGFIVNGKRNYFIGTSCSTPLYAGLFAALASALGGGGEGGVLFGPLNTVLYQIDRGVYRDITFGHNDSGDMPACAYFAAGEGYDTVSGLGSVDGRRTLEELRRIYWPKTKGFGCFRN
What is the function of this protein?
Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
What are the official names of this protein?
Tripeptidyl-peptidase sed5, Sedolisin-E.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ACPS_BURTA
Sequence: MAIYGIGTDLAQVSRIAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRALQTLNRPSGEPYVVASGGLAEWLDARGITARVTVSDERDYAVTFVVAEAPDDVVAARSGAAS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI_MEDSA
Sequence: MAKNVAIFGLLFSLLLLVPSQIFAEESSTDAKEFVLTLDNTNFHDTVKKHDFIVVEFYAPWCGHCKKLAPEYEKAASILSTHEPPVVLAKVDANEEHNKDLASENDVKGFPTIKIFRNGGKNIQEYKGPREAEGIVEYLKKQSGPASTEIKSADDATAFVGDNKVVIVGVFPKFSGEEYDNFIALAEKLRSDYDFAHTLNAKHLPKGDSSVSGPVVRLFKPFDELFVDSKDFNVEALEKFIEESSTPIVTVFNNEPSNHPFVVKFFNSPNAKAMLFINFTTEGAESFKTKYHEVAEQYKQQGVSFLVGDVESSQGAFQYFGLKEEQVPLIIIQHNDGKKFFKPNLELDQLPTWLKAYKDGKVEPFVKSEPIPETNNEPVKVVVGQTLEDVVFKSGKNVLIEFYAPWCGHCKQLAPILDEVAVSFQSDADVVIAKLDATANDIPTDTFDVQGYPTLYFRSASGKLSQYDGGRTKEDIIEFIEKNKDKTGAAHQEVEQPKAAAQPEAEQPKDEL
What is the function of this protein?
Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.
What are the official names of this protein?
Protein disulfide-isomerase, PDI.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CHS1_DAUCA
Sequence: MVTVNEFRKAQRAEGPATVLAIGTATPPNCVDQSAYADYYFRITNSEDKPELKEKFRRMCEKSMINTRYMHLTEDLLKQNPSFCEYMASSLDARQDIVVNEVPKLGKEAALRAIKEWGQPKSKITHLIFCTTSGVDMPGADFRLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKNARVLVVCSEITVITFRGPNDTHLDSLVGQALFGDGAGAVIVGSDPVIGIEKPLFEIVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIRKSLVEAFKPLGISDWNSIFWIAHPGGPAILDQVETELSLKPEKLKSTRQVLRDYGNMSSACVLFILDEMRKASAKDGHRTTGEGLDWGVLFGFGPGLTVETVVLHSVPP
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, DcCHS1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RS18_YERE8
Sequence: MARYFRRRKFCRFTAEGVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARCIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CC167_MOUSE
Sequence: MTKKKRENLGVAQEIDGLEEKLSRCRKDLEAVTSQLYRAELSPEDRRSLEKEKHTLMNKASKYEKELKLLRHENRKNTLLSVAIFTVFALLYAYWTM
What are the official names of this protein?
Coiled-coil domain-containing protein 167.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BR1B_ODOVE
Sequence: MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDEPDEMNVEVEKRFLPLIAGLAANFLPKIFCAITKKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-1Vb, brevIVB, 1VEb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RDH14_MOUSE
Sequence: MAVASVAAALLAALGGALWLAARRFSGPRNQRQQGGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRQELCQAGGAGPDGTDGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGEINFEDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAFFKTPLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGILK
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Displays high activity towards 9-cis, 11-cis and all-trans-retinol.  Shows a very weak activity towards 13-cis-retinol.  Has no activity towards steroids.
What are the official names of this protein?
Retinol dehydrogenase 14, Alcohol dehydrogenase PAN2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ACCA_CITK8
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIQEPLGGAHRNPEAMAASLKAQLLADLADLDVLSKDDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_GEOSW
Sequence: MEKLYALFGCPVHHSLSPIMHNDAFQNMNIAAHYHAFHVEPERLKDAIAGVRALGISGVNVTIPHKTAVMPLLDEVDPTARRIGAVNTIVNRNGRLIGYNTDGPGYVRALEEEINVDIKEKRILLIGAGGAARGIYVSLADRGAKQIDICNRTVSKAKQLIDECNASVSSVVYSLNEAEERLGEYDILINTTSVGMYPNMEEMPLSLANMKEETIVSDIIYNPLETKWLKEARKRNGIIQNGVGMFVYQGALAFEKWTGIFPDVQRMKKIVIEQLRG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NU4LM_RUSUS
Sequence: MSLVYMNIMTAFMVALAGLLMYRSHLMSSLLCLEGMMLSLFVMASLTILNSHFTLASMMPIILLVFAACEAALGLSLLVKVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ELIB_PHYME
Sequence: TACTTTQQTAAYKTLVSILSESSFNQCSKDSGYSMLTATALPTNAQYKLMCASTACKSMINKIVVLNPPDCDLTVPTSGLVLDVYTYANGFSTKCASL
What is the function of this protein?
Induces local and distal defense responses (incompatible hypersensitive reaction) in plants from the solanaceae and cruciferae families.  Elicits leaf necrosis and causes the accumulation of pathogenesis-related proteins.  Might interact with the lipidic molecules of the plasma membrane.
What are the official names of this protein?
Beta-elicitin MGM-beta.
What is the protein family that this protein belongs to?
Belongs to the elicitin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3A_ZYGRC
Sequence: MAVGKNKRLSKGKKGLKKRVVDPFSKKEWYDIKAPSTFKNRNVGKTLVNRSAGLKSASDTLKGRVVEACLADLQGSEDHSFRKIKLRVDEVQGKNLLTNIHGMDFTTDKYRSMVRKWQTLIEAQVTVKTSDEYVIRVFAIAFTRKQPNQVKKTCYAQSSHIRAIRKVFSEILTREVQNSTLAQFTSKLIPEVINKEMENATKDIFPLQNVHVRKVKLLKQPKFDLGSLMALHGEGSDETGKKVSGFKDEILETV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA2_NOSS1
Sequence: MNLDLLGWSDFFTHSFVPYRQQGFSVGRVAIEYRNTYIVYSKQGELAAKVTGKLRHQATQPQDFPAVGDWVIIQTRESEGCATIHGILPRKSKFSRKTVGSKTEEQIVAANVDTVFLVCGLDGDFNPRRIERYLILAWESGANPVIVLNKADLCNSLDECISEVEAVAIGVPILVLSATNNQGIDTLKAYLQPGQTVALLGSSGVGKSTITNQLKGASVQAVQPVRQGDDRGRHTTTNRELILLPTGGLIVDTPGMREIQIWAGDESLQETFADIETLAPECRFRNCQHHNEPGCAVQQALLEGELDYSRFLGYQKLQKELNYLVRKQEQRAQLAQKERWKKIHKAMRNHHQY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASCL5_HUMAN
Sequence: MPMGAAERGAGPQSSAAPWAGSEKAAKRGPSKSWYPRAAASDVTCPTGGDGADPKPGPFGGGLALGPAPRGTMNNNFCRALVDRRPLGPPSCMQLGVMPPPRQAPLPPAEPLGNVPFLLYPGPAEPPYYDAYAGVFPYVPFPGAFGVYEYPFEPAFIQKRNERERQRVKCVNEGYARLRGHLPGALAEKRLSKVETLRAAIRYIKYLQELLSSAPDGSTPPASRGLPGTGPCPAPPATPRPDRPGDGEARAPSSLVPESSESSCFSPSPFLESEESWH
What is the function of this protein?
Transcription factor.  Probably binds E-box motifs 5'-CANNTG-3' in complex with transcription factor TCF3/E12.  Negatively modulates transcription of target genes such as CDH1/E-cadherin, perhaps by recruiting the PRC2 repressive complex to regulatory elements.  Regulates ameloblast development and tooth germ growth, perhaps acting by positively modulating migration of inner enamel epithelium (IEE) cells.  Plays a role in enamel formation.
What are the official names of this protein?
Achaete-scute homolog 5, ASH-5, hASH5, Class A basic helix-loop-helix protein 47, bHLHa47.
What are the subcellular locations of this protein?
Nucleus.