PharMolix/UniProtQA huggingface dataset:
Protein: RS4X_MONDO
Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKIDGKVRTDTTYPVGFMDVISIEKTGEHFRLVYDTKGRFAVHRITAEEAKYKLCKVRKTFVGTKAIPHLVTHDARTIRYPDPLIKMNDTIQIDLETGKITDFIKFDTGNMCMVTGGANLGRIGVITNREKHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEERDKRLAAKQNNG
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S4, X isoform.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: PALMD_PIG
Sequence: MEEAELVKERLQAITDKRKIQEEISQKRLKIEEEKLRHQHLKKKALREKWLLDGIGSRKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTNEEAILKKLKSVERTTEDIIRSVKVEKEETSGASIEDIYANIPDLPKSYVPSRLRKERNEGIEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEDLLRQASERNSKSPTEYHDPVYANPFCRPTTPQREKATPGPNFQERIKMKARGLGKDMNGSIHTMNNGLSEERGSSVNHISPIRPIPHPRSMTQQAEERPHSPQKRQMTPWEESDVTQDKCAPSAKSQLSPGEAPVGKSERQGSSPTCQEDEEDVRYNIVHSLPSDVEDTEPVTMIFMGYQRADDSEEEKKLLTGYDGIIRAELVVIDDEEEEGEGEAEKPSYHPIAPHSQVFQPAKPTPLPRKRAEVNPHENTNHKSPHKNSISLKEQEESLGSPIHQSPLDIQIAGDGTEDPSLTALRMRMAKLGKKVI
What are the official names of this protein?
Palmdelphin.
What is the protein family that this protein belongs to?
Belongs to the paralemmin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, dendritic spine.
Protein: HIS6_SULNB
Sequence: MDYFAKRIIPCLDVNEGRVVKGVNFVGLRDAGDPVEVAKRYNEEGADEITFLDIGASHEGRDTIVDVVKKVAQEVFIPLTVGGGIRELPDIYNLLNVGCDKVSINSAAIKRPEFIEEGAKRFGSQCIVVAIDAKRVGNGKWHIFTHGGRNDTGIDALQWAKEAYERGAGELLVTSMDADGTKAGFDNELNRKIGELVNIPVIASGGAGTMQHIEEAFTLGNADAALAASIFHFREIDIMELKHYLKTKNIPVRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1670_BRUA2
Sequence: MLYYVLVFLVVALVAGALGFGGIAGASAGIAQILFFVFLALLVISLIASAIRKA
What are the official names of this protein?
UPF0391 membrane protein BAB1_1670.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYS_STAAT
Sequence: MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_NOVAD
Sequence: MSNPIYLALDLPRLDAAVALAQKVKGHVGGLKLGLEFFCAHGHHGVHEVAKVGLPIFLDLKLHDIPNTVAGAMQSIHVLEPAIVTIHAGGGRAMMEDAKAAAGEHTKVVAVTVLTSLDDADMSTMGVGGSAYDQAIRLADLAQEAGLDGIVCSGHEVGAIHKRWKNGFFVVPGLRPAEGKLGDQKRAVTPRAARDAGASVLVIGRPISRAEDPVAAARAIEATL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TRPF_CHLT3
Sequence: MVKVKICGLITQEDAMLACQYGADLLGFNFYEKSPRYISPAKAAEIIKTLPSNVASVGVFVGKEANEINQICEEAMIDIAQIHDESLCAKDFTKLRPKIIKAFRVQNTFDTREIRRFYEQTGVNTFIFDAFQKDLYGGTGKRLDVELAHKVFKEIEGFGYGFLAGGLNEKNVETTVRLLKPYGVDVASGIESEPGKKAHDKMALFIREAKKSLCLEPGY
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: KIC_ARATH
Sequence: MEPTEKSMLLETTSTTKMETKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMMEDAETWLEKALTQELCNHNLSSMP
What is the function of this protein?
Calcium-binding regulatory protein that interacts with kinesin motor protein KCBP in a calcium-dependent manner.  Inhibits KCBP microtubule binding activity and microtubule-stimulated ATPase activity.  Involved in the regulation of trichome branching through its interaction with KCBP.
What are the official names of this protein?
Calcium-binding protein KIC, KCBP-interacting calcium-binding protein.
Protein: ASA1_LACTC
Sequence: MQGHQPAAYTLRKHETEVTCLKVVSWEPYPVLASGDAKGELYLWNLVTRRPFAGYKLETKAQIIYIKWLNNYLIVLSKDHTLRFLQLHNETAVAIRGWAGNQFELQSFKIVYEVPVNTLNFANVVVTHMRESQYRLWCCNTMDSESIDVYEFDVKEQRSLRRLVSGINLYKAIIKAGNWSTGESLDKTGIVMCFLEHNGVVYLGYECGFVLGLQLVERSGENPTIVVSYVSSVHYPEPVLSLCYNEREEVILSSSTNDAIGVHALQAHSVNVSESEIAFFSIEEGIAIKRDLTLINKSIHLPTSKIGHLGCVDGRLIAVDWSGRTLVCEKDETKFCFSKQRSNVLVDESSAGTFDQGKAPRCHIKATSMACIGKQTLRELRGIRRGEKRRTELCANRSWCFTGYEDGSVIMQSFET
What is the function of this protein?
Component of the ASTRA complex involved in chromatin remodeling.
What are the official names of this protein?
ASTRA-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ASA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSSR_STAAM
Sequence: MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFMLAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGYKVENHV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1617_BACC3
Sequence: MKVIAVTGYKPFELGIFKNDHPGVECIKKALRRKLTAFVEDGLEWVIISGQLGVELWAAEVVFEIQVEYPDLKLAVFTPFLEQEEGWKEDNREYYEFILSQADHVDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVEAAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BCA_1617.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: END4_BACVZ
Sequence: MLKIGSHVSMSGKHMLLAASKEAVSYGANTFMIYTGAPQNTRRKKIEDLNIEAGRAHMKENGIDEIVVHAPYIINIGNTTNPATFELGVDFLRSEIERTAAIGARQIVLHPGAHVGAGAETGIKKIIEGLNEVIVPGQNVQIALETMAGKGSECGRSFEELAEIIAGVTHNEHLSVCFDTCHTHDAGYDVANDFDGVLNEFDKIVGIDRIKVLHVNDSKNIKGARKDRHENIGFGEIGFDALQYIVHHEQLADIPKILETPYVGEDKKNKKPPYRFEIEMLKEKQFDKELLEKISAQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: CBPA6_HUMAN
Sequence: MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP
What is the function of this protein?
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas.  May convert inactive angiotensin I into the biologically active angiotensin II (PubMed:18178555).  Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine (PubMed:20855895).
What are the official names of this protein?
Carboxypeptidase A6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
Protein: RL19_BRUSI
Sequence: MTDIIRQLEAEQAAKIEEKRKLPDFQPGDTVRVQVRVTEGTRTRVQAYEGVCIARSGAGLNENFTVRKISYGEGVERVFPVYSPIVEGVEVVRRGKVRRAKLYYLRGLTGKAARIAEKKDNRTKAERAADKLAAAKAEAAKTAAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ZDHC6_DANRE
Sequence: MNILSAIIVFENLHEVKRLFHWGPIIALTVIGVCSSMAILDSIIWYWPLDTTGGSINFIMLINWTVLILYNYFNAMFVGPGYIPLEWKPEKQQDIMYLQFCRLCQGYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHLNHAYFTSFLLLAPLGCIHAALIFIMTMYTQLYDRISFGWSSVKIDMSAARHIHHPIMPFSIAAFAATLFALGLALGTTIAVGMLFFIQMKVILRNRTSIEAWIEEKAKDRIQYYQTGEDFIFPYDLGSRWENFKQVFTWSGAPMGDGIEWPVHEKCDQYTLTIEQLKQKHDKRQRSVEYRVVEEYNGACCPLGKGLNTFFRTPCTEEPRIKLTKGETIFATRGTKWWMYGDKVLNEEQAKAGVRIRGWFPRRCVEKCLYDSANNSTSEEKKEQ
What is the function of this protein?
Endoplasmic reticulum palmitoyl acyltransferase that probably catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes (By similarity).  Could also function as a stearoyltransferase (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC6, DHHC domain-containing protein 6, Stearoyltransferase ZDHHC6, Zinc finger DHHC domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DGT1B_DEIRA
Sequence: MTAIVEPTWEERRTPEAAHEDDARSQYRKDYSRIIHSAALRRLQTKTQVLGLGDSDFYRTRLTHSLEVAQIGVGILLEIQRRFAGSNIEKYLPDERLLEAICLSHDYGHPPFGHGGERALNFAMREYGGFEGNAQTFRILSKLEKYSQNSGLNPTRRTLLGVLKYPTTYSNSMTNDFRRGTDIDKYPDAELKPPKCIYDCDLDVLDWVLKIFCSEDVTEFKKLDYKCKPLHKSLDCSLMETADDIAYTVHDLEDCIKLKLINREMWDAYIKSADYSEATRLEIEKWNQRIFSKEGNLVKQGISNMVYFFIHSVIQYEHEELSHPILKYGFKLGEEAARLRSAIQKIITNEVIKTHRVRVLESKGQRMIFSIFGELVRDPESFLPRETLDKYNKATGNLRMRVICDYVSGMTDEYATKTYQRFFTPKFGSVFDV
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: HLDD_CUPPJ
Sequence: MTIIVTGAAGFIGSNLVKGLNARGENHIVAVDNLHRADKFHNLVDCEIRDYLDKDDFLSRFERGEFGRVRAVFHLGACTDTMEQDGRYLMENNYRYSKTLMELCLAQDTQFIYASSAAVYGESHSFREAREYERPLSVYGYSKFLFDQAVRNRLDGALSQVVGLRYFNVYGPGEAHKARMASIVCQQFEQFRAEGTVKLFGEHGGHGPGCQSHDFVSIDDVVKVNLFFLDHPRRSGIFNVGSGHARSFNDVACVVVNTLRAAEDKPPLALEELVQEGLLEYLRFPDALRGRYQSFTQSDSSRLREAGYTAPFVAMEEGVARYCQWLLERGQ
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: PDXA_ZYMMO
Sequence: MKPLAVTLGDPSGIGPEIVAKAWSRRKSDQIMPFFAIGSAASIQAVSSIPVVAITDPNEAISIFDQALPVWDIPSKETITPGKPNKAGAEVAFAALEKGVALVKQGQASALVTAPVSKAELYQVGFTFPGQTEFVANRCGIAADDAVMMLAGPDLRTVPLTIHIPYRDVLEQLTPKLIISRARVTVEDLKRNFAIPSPRLVVAGLNPHAGENGTIGREEIDSIEPAIRQLQAENIDIKGPFAADTLFSPRARATYDVALCPTHDQALIPIKTINFDNGVNTTLGLPIIRTSPDHGTAFPLAGKNKADEGAMVAALVMAANSAHNRQAYAQNSIDG
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1062_STAA8
Sequence: MAKQATMKNAALKQLTKDADEILHLIKVQLDNLTLPSCPLYEEVLDTQMFGLQKEVDFAVKLGLVDREDGKQIMLRLEKELSKLHEAFTLV
What are the official names of this protein?
UPF0358 protein SAOUHSC_01062.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: YOCL_BACSU
Sequence: MKKMFRSLIRHCLKPELDKLRECEERLSVIEKQKQSSKQESEETYIHIETLNVEKVDYHLEFGELTIDELSGRLNIGATYYIPPEEKDKKCQRKPEAPSTPAVTIRSKRQ
What are the official names of this protein?
Uncharacterized protein YocL.
Protein: PRS8_CAEEL
Sequence: MAPPASTASSADPSKPTAQKLTEESDEKTLRKYFSTKVDDAQQKVADKSQNVRRLQAQRNELNTKVRMLKEELQQLHEQGSYVGEVSKAMDKKKVLVKVHPEGKYVVDVDKSIDINSLNTGARVALRADSYALHKLLPNKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLFGPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRVEGSSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPAPDEKARADILKIHSRKMNLMRGINMAKIAEQIPGASGAEVKSVCTEAGMFALRERRIHVTQEDFEMAVGKVMQKDSEKNMSIKKLWK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins (PubMed:30265660).  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required (PubMed:30265660).  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair (By similarity).  Belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides (By similarity).  In addition, regulates gene expression in response to bacterial infection (PubMed:30265660).  Binds to the GATA transcription factor elt-2 to control its transcriptional activity and thus the expression of elt-2-dependent genes in response to infection by Gram-negative bacteria such as P. aeruginosa (PubMed:30265660).
What are the official names of this protein?
26S proteasome regulatory subunit 8, 26S proteasome AAA-ATPase subunit rpt-6, Proteasome regulatory particle ATPase-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECX_MYCSJ
Sequence: MTSFPHPSTSESGPDPDSEPNREEQAHAYCLRLLTARARTRAELSGKLTQRGYDEPVVARVLDRLVEVGLVDDEDFAEQWVRSRHLYAGKGKRALAAELRRKGVDDEVISSSLADIDAGAERDRAERLVRDRLRREKLDDEPGSDLKVKRRMAGMLARRGYSQSMALDVVTVELAGERERRRV
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRP10_YEAST
Sequence: MSGKPPVYRLPPLPRLKVKKPIIRQEANKCLVLMSNLLQCWSSYGHMSPKCAGLVTELKSCTSESALGKRNNVQKSNINYHAARLYDRINGKPHD
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein MRP10, mitochondrial, Mitochondrial small ribosomal subunit protein mS37, YmS-T.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS37 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: BIOB_CITK8
Sequence: MAHHPRWTLSQVTELFNKPLLDLLFDAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRSYQERLDTLDKVREAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNEDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTSVLAGDNEQQQRLEQALMTPDTDDYYNAAAV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YBGC_SHIFL
Sequence: MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHHFSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENTLLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ
What is the function of this protein?
Thioesterase that appears to be involved in phospholipid metabolism.  Some specific acyl-ACPs could be physiological substrates.  Displays acyl-CoA thioesterase activity on malonyl-CoA in vitro, catalyzing the hydrolysis of the thioester bond (By similarity).
What are the official names of this protein?
Acyl-CoA thioester hydrolase YbgC, Acyl-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MMPC_CAEEL
Sequence: MRLIYVIAILLVSTCQAGFFSSLVSRFTGGGNSSPSSSSSSSSFSNSRKPSLSDEKARSYLQTFGYVPPSNSLQSRNGMAGDIQSAEQVFKSAIRKFQEFAGIAKTGFLDAATKAKMALSRCGVTDAPLALTSGSSQFKWSKTRLTYSIESWSSDLSKDDVRRAISEAYGLWSKVTPLEFSEVPAGSTSDIKIRFGVRNHNDPWPFDGEGGVLAHATMPESGMFHFDDDENWTYKDARKIHNNEATDLLAVAIHEGGHTLGLEHSRDENAIMAPFYQKTTDSSGNYVYPNLKSDDISAIQAIYGAGSGRSSSGSDFGGSSGGGSRTTARPTTTTRSWFGRFFGDDDDDVRSRTTTRRTTLWPTTQSPFSGDDWGSGSGSSGRGGSSSGSSGGGCPSHIDAYTPSSSFSYAFSGSQVYTISGTKVTKVQSIHDLFPSAPTPVNAALWNPISGSMLLFSSNRVYSYYFSNIRQIFQMDSGFPKTLPSDLGFSVSGALRWINGHQILMSSGDEFAVYDEFWNQVTLKNRISSYFPNLPRGVKGVESPAGSVITAFTSNQVFEYNSRTKSIGRQSGFSSYIAC
What is the function of this protein?
Metalloproteinase.
What are the official names of this protein?
Matrix metalloproteinase-C, MMP-C, MMP-C31, Zinc metalloprotease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL25_MYCTU
Sequence: MAKSASNQLRVTVRTETGKGASRRARRAGKIPAVLYGHGAEPQHLELPGHDYAAVLRHSGTNAVLTLDIAGKEQLALTKALHIHPIRRTIQHADLLVVRRGEKVVVEVSVVVEGQAGPDTLVTQETNSIEIEAEALSIPEQLTVSIEGAEPGTQLTAGQIALPAGVSLISDPDLLVVNVVKAPTAEELEGEVAGAEEAEEAAVEAGEAEAAGESE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PPNP_SHEFN
Sequence: MSMLQQVSVAKKANVYFNGKVISRSVVLADGSKQTFGVVLPGEYEFSTAQGEIMQVISGKFDVLLPGKTEWVAYAEASQFELAPNVSFSIRTDQISEYCCQYI
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: FMT_NOSS1
Sequence: MKIVFFGTPEFAVPTLEKLLINPEFDVLAVITQPDKRRERGNKLTPSPVKNVAMSYSQWENIAHDLPVWQPERIKKDTETLNRLKELDVDAFVVVAYGQILPQKILNIPKLGSVNVHGSILPQYRGAAPIQWCLYNGETETGITTMLMDVGMDTGAMLLKATTPIGLLDNADDVAQKLSVIGGDLLIETLHKLQQKEIQPIPQDNAAATYASLIQKQDYGLDWSRSALQLHNQIRGFYPNCITTFRNQPLKITASFPLGAAYREELPPELQKMLQKLPDLSQISGSPGEVVSITKGVGAIAQTGEGLLLLREVQLPGKRPQSGWDFVNGTRLTVGEVLGNGS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HGNAT_HUMAN
Sequence: MTGARASAAEQRRAGRSGQARAAERAAGMSGAGRALAALLLAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNLTVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKNIHNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWISKAISSRETDRLINSELGSPSRTDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGGKYWYFKHASWNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQWLLILVLEGLWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSSAVLYHTEVAYDPEGILGTINSIVMAFLGVQAGKILLYYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVATALWVLIAYILYRKKIFWKI
What is the function of this protein?
Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase.
What are the official names of this protein?
Heparan-alpha-glucosaminide N-acetyltransferase, Transmembrane protein 76.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Note=Colocalizes with the lysosomal marker LAMP2. The signal peptide is not cleaved upon translocation into the endoplasmic reticulum; the precursor is probably targeted to the lysosomes via the adapter protein complex-mediated pathway that involves tyrosine- and/or dileucine-based conserved amino acid motifs in the last C-terminus 16-amino acid domain.