PharMolix/UniProtQA huggingface dataset:
Protein: FPG_ECOL5
Sequence: MPELPEVEAIRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PT1_MYCPN
Sequence: MKKLSGIGVSDGMALAKAFLVKTPEFAVNKYLKHQLTKAQAKRLLDSAFKKAVKDLEEIKEITVNNINTEAGMIFDAHIQMLNDPTITEQLEQQLAQNVHPVIAVDTVFSQTATMFSQMQDKYFQERAADILDLRQRLLAYLTGQKPHDLVKIKSDVIIVAHDLTPSQTATLNKKYVKGFLTEIGGRTSHAAIMARSLEIPAVVGIKGITTKVKDGQIVGVDGRKGIAGLDLNSKDTTEWKKQKALEEKYQQELKQYTNKETVTLDGHAVVVAANIGNVKDMELACQYNTNGVGLFRTEFLYMNSQEWPDEETQYQAYKAVLEQAHGDLVIIRTLDIGGDKKLNYYEFPHEDNPFLGYRALRLTLDKQDIFKTQLRALLRAADHGQLGIMFPMVATLDELLQAKQLLNQVHQELGGNKQFKLGIMIEIPAAVLAANTLSHHVDFFSIGTNDLIQYSFAADRMNKNVSYLYQPLNPALLKLIYLTIEGGKVNDIWTGMCGEMAGEPLAIPLLLGLGLKEFSMSASSMFKARMIIAKLNYTECQTLAQKALTLANAKEVEKLVEKFFKKKDIFI
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_ALKOO
Sequence: MKAINRLRKNEDFRKVYKKRKSMANKLLIIYILENGYNFNRVGFTVSKKVGKSVIRSRVKRLLNESYRLNNEKVKQGYDIIFVARNTCVDASYKEIESAILHLLKKMNLINSAV
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: KLPA_EMENI
Sequence: MENVQSRMQGSRIPGLKEMNPSGTNARSRLPQPGAIANKPTAVPQLARTRSTTESTRIGAGPPSAARSVNGATKAHTRANSYANSSTLTRSASAASRPRGPLSSSTSGRPKTSMSTSRRPNGHALPRPATSLDTHQEERSYGGLGKRGEWDQDEREQNLESLFETFVSRISQQGQESSGLKDALEVYKSRVGELEEAKSEQTEQNIRLKVELDVSKSRLAEAEDALKNAQRDHEIAIDELMSRQRAECESVRYESQKSLDALKAQHESELKELRRQFERELEDEKCARVRELNQLHSKTALDAQLSQIELDKTIKELAATREDLQSLRTELDRERKNTNNLRQNLDTAASNSVTLESTISALKARIEFLESGREEQSEAFERLNQQMMDAMAETNAAKEKLRREETLRRKLHNQVQELKGNIRVFCRVRPTLENEGASDAAQFTYPDEGEDSKEINIIGPEEKSSFGTVTRKNHNFSFDHVFGPSAQNSDVFDEISQLVQSALDGYNVCIFCYGQTGSGKTHTMSSLDGMIPRAVHQIYETATSLEEKGWRYTMEGNFVEVYNENLNDLLGKAEELDKKKLEIRHDMQRGKTTITDATTVQLESPEMVESLLKRAAANRSVAATKANERSSRSHSIFILKLIGENYITGERSEGTLNLVDLAGSERLSHSGATGDRLKETQNINRSLSCLGDVIAALGQGKKDGHIPYRNSKLTYLLQFSLGGNSKTLMFVMVSPLQAHLSETLTSLKFATKVHNTHIGTAKKQTRVRDV
What are the official names of this protein?
Kinesin-like protein klpA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y511_STAAS
Sequence: MKKIMITGALGQIGTELVVKCREIYGTDNVLATDIREPEADSPVQNGPFEILDVTDRDRMFELVRDFEADSLMHMAALLSATAEKNPILAWDLNMGGLMNALEAARTYNLHFFTPSSIGAFGDSTPKVNTPQVTIQQPTTMYGVNKVAGELLCQYYFKRFGVDTRSVRFPGLISHVKEPGGGTTDYAVEIYFKAVREGHYTSFIDKGTYMDMMYMDDAIEAIIKLMEADDAKLETRNGYNLSAMSFDPEMVKEAIQEYYPNFTLDYDVDPIRQGIANSWPDSIDTSCSRGEWGFDPKYDLASMTKLMLEAIEQKDTVKNNN
What are the official names of this protein?
Uncharacterized epimerase/dehydratase SAS0511.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: MIA40_RAT
Sequence: MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEDIKGSDCIDQFRAMQECMQKYPDLYPQDEEEEEEAKPVEPVEETADTKASAAKEQGASS
What is the function of this protein?
Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes.  Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17, COX19, MICU1 and COA7.  Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS).  Required for the import of COA7 in the IMS.  Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria.  The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS.  Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system.  Mediates formation of disulfide bond in MICU1 in the IMS, promoting formation of the MICU1-MICU2 heterodimer that regulates mitochondrial calcium uptake.
What are the official names of this protein?
Mitochondrial intermembrane space import and assembly protein 40, Coiled-coil-helix-coiled-coil-helix domain-containing protein 4.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: GSA_METPP
Sequence: MADSRNASLFERARRSIPGGVNSPVRAFRAVGGTPRFIARADGAYLWDADGKRYIDYIGSWGPMILGHGHPAVLEAVQKAATEGFSFGAPTEREVELAEEILKLVPSAEQVRLVSSGTEAAMSALRLARGATGRSKIVKFEGCYHGHADALLVKAGSGLATFGHPTSAGVPTEVVQHTLVLTYNDVTGLEAAFSAHGAEIACVMIEPIAGNMNFVRAGLPFMKRLRELCTQHGALLVFDEVMTGFRVALGGAQSLYAKAIPGFKPDLSVFGKVIGGGMPLAAFAGPRAIMEQLAPLGPVYQAGTLSGNPVATACGLATLREIQKPGFFESLAAGTRDLLDGLLHAATAAGVPMVGDCEGGMFGFFFPKTAQAALPQNYVEVMATDGERFNRYFHGMLDRGVYLAPALYEAGFVSAAHTPADIEATLAAARATLAAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLH22_FORAG
Sequence: MCTTAWATAQPVIKPPKGRIAIIADGNSPDPDDLGGTAISLALLRATSLESRLVHYSHSCDLVRVNRISEAAEYERHAMMQTACDGTARRWGGFENLTFFDAKWQLDETIKDLSKAINASSAEDPLWIIEAGEPDIIGFALAASEKEKHQYVKVVTHHPANDDAGDFYTWQSILDFGVEEVRIPDQNINLKVDESEWDWAKNHSDDRMKFVWLMGKMAEVDDVVKFQKGKWDCSDAGMVLYWITGATNGGVKQGSVTQVKTILEGFLSQNNN
What is the function of this protein?
May be involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
What are the official names of this protein?
Uncharacterized protein P22, Polysaccharide utilization locus H protein P22, PUL H protein P22.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1086_ALISL
Sequence: MFGGKGGMGNLMKQAQQMQDRMQKMQEEIGNMEITGESGAGLVKVTITGSHSVRRVEIDPSLMEEDEKEMLEDLIAAAFNDASRRIEETQKERMAGVTGGMQMPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein VSAL_I1086.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DPOL_ADES1
Sequence: MEASTTTVKARSTHYICGHAGDSFVKIIYYKDKVKAVVSYLNMNDYLNTYALKCVIPEKITKDFFSSCPDDLLYSTLASIQRGYSPKKKEELGGKWEPLLLLYHRGEEYIIRAVVPQRRCEDCGKQFVSSHQCNVRRREFYHHAVLPDTKTWWKPIKFSPIGALSNAKRLFIIYDIETYTFHSGYGKQLVPYLLVMQFKGDSRLRCEAEKIALECGFQPYRQCFMMLNKARDVIGHKFKDMRVQLQKRAASDIWSRYREKHDILSEEGVSYAQLEAMAKDNLLKTDAEPEFTEIIVVGHNITGFDEIVLASHVLEGLPKDEELQMFKITRNFMPRAGKLLFNDVIMALPNAAFQKPKQSTFQRWKTGDLRPEDLKWEGVRFMVRDTVLLTHSSLRNAAQAYQLEVSKGHCPYDALNQYFMVGTYLCDENMYPAREYWSSDEEYLENKPPDGEKYDLVQKAVDYCVNDVKVTVALVKKLCSGYQQFCDEVLKLDCTFNVFQRPTISSTTHAMFKQMFYKSEPSAVGKFLPNLEAPSEVMYEHIRKSVRGGRCYPSFLGVFTEPHLCYDICGMYASALSHPMPYGPTLSPFDSAVAIAEFQRKLDGQSELSYFDPDIFPMIVVADAFPPSLHCLDVLPPLCSKRSGKLCWTNEPLLGEVLTTVDLIMLKNRGWRVKLIQNAECYAVWREWRPLCREYVSINIAAKEKADREKNQTQRSISKLLSNALYGSFATRLDNKQVVFMDDMSSTTQSELRSGKASIVSMTSVCSRSLPQKDTSFWERYFNLPQVEDSISAELNDEPETEPFIGGERSHVIYKPITFLSAECDNLLLATVQSNSDWVKNDRYATQVASFVLAWSRAFMSEWATILYGEDIGVPYEQRKLKSVYGDTDSLFLTGEGHRLMITKGRHKLKSSGNSLVYRDDGNLAWLVECETSCPSCKSDSFSSESCFLAPKLYALKDTTCPSCGLVSGGKLRAKGHAKSCITYDVLKSCFLDHYLLERPTEQYQSERTPIKRTLANGSANSAPFTVVEKQLARVIRPWNDPTMARGTDLSQGFLLFPYDQKRPNPRPQEPLLENPFWDDSSQTA
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RPO6_THEAC
Sequence: MKYTKFEKARIIGARALQIAMGAPVIIDVPKNIIDPVDIAMLEFENNVIPITIKKASKILN
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPGP1_MOUSE
Sequence: MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTNHEISSLPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDTALGHLVFSLKYDVIGDQEHLRLLLRTKCRTHHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDDDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFTPNNPDLAKAAGISLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRVESAAQRTEVLQGFSRSSSSASSFTSVVEETEGVDGDDTGLESVSSSGTPHKRDSFLYSTWLDDSVSTTSGGSSPGLTRSPHPDVGKSGDPACPEIKIQLETSEQHTPQMGC
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
What are the official names of this protein?
Rap1 GTPase-activating protein 1, Rap1GAP, Rap1GAP1, ARPP-90.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: SYAC_HUMAN
Sequence: MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEADLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARGLEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKAVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAESLKKCLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQFIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQLRLGDVKN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala) (PubMed:27622773, PubMed:27911835, PubMed:28493438, PubMed:33909043).  Also edits incorrectly charged tRNA(Ala) via its editing domain (PubMed:27622773, PubMed:27911835, PubMed:28493438).
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, Alanyl-tRNA synthetase, AlaRS, Renal carcinoma antigen NY-REN-42.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOIP2_MOUSE
Sequence: MSQSLKSQNTNMSDSGCRDPVGDSQNVLENDPSINSQTQDTRVTPNNTAEAQPLQPTSDLKEDHHEIGARAQEHTDTGDRSESPEEPALEKPPLDKAELESSPSSQDTELGHHPHSEHGGGDALDLDPNCSQSDLGGRADAHLESSSVASPEGAGDRGEADEHLESSSAAPTEGAGDRGEAGQELLAEDSTDGQSLGHSNTGPGNQDSLRRRLPVPEAGSHEEETELVKEKQEVAQDTLRKTDKKSLWTYGSVFLGCLIVAVVLSSVNSYYSSPAQQVPQNPALEAFLAQFGQLKEKFPGQSSFLWQRGRKFLQKHLNASNPSEPATIIFTAAREGKETLKCLSYHVANAYTSSQKVTAVSIDGAERALQDSDTVKLLVDLELSDGFENGHKAAVVHHFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLEASVSPREIEEKVRDLLWAKFTNSESPTSYSHMDSDKLSGLWSRISHLVLPVQPVRNIEERGCLL
What is the function of this protein?
Required for endoplasmic reticulum integrity.  Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity (By similarity).
What are the official names of this protein?
Torsin-1A-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the TOR1AIP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope.
Protein: RS5_PHOLL
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMKTVALNSGTLYHPVKGAHTGSRVFMQPAHEGTGIIAGGAMRAVLEVAGVRNVLAKTYGSTNPINVVRATLDALDSMKSPEMVAAKRGKSVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PAND_MYCSS
Sequence: MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAITGARGSGVIGINGAAAHLVHPGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGADPAMVPDTAVDLMSPR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BROX_PONAB
Sequence: MTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDLSCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWHTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPTVKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGLVEPIPFEFPPTSAQWTPETLAAFDLTKRPKDDSTKPKPEEEVKPVKEPDIKPQKDTGCYIS
What is the function of this protein?
Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane.
What are the official names of this protein?
BRO1 domain-containing protein BROX, BRO1 domain- and CAAX motif-containing protein.
What is the protein family that this protein belongs to?
Belongs to the BROX family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: DAPD_ZYMMO
Sequence: MSDLIKIIDQAFEDRANITPATKGEVVEAVEEALSLLDSGKRRVAELGDNGEWVVNQWLKKAVLLSFRLTGNAPMNGGYDKVPLKFTNWSEDQFKQAGFRAVPGAVVRRGAFISKGAVLMPSFVNIGAYVGENTMVDTWATVGSCAQIGANVHISGGAGIGGVLEPLQAGPVIIGDNAFIGARSEVAEGVTVGEGAVLSMGVFIGASTRIIDRATGEIHMGKVPPYAVVVPGSLPGKPLPDGRPGPSLYCAVIVKTADERTRSKTSINQLLREAQN
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL4_ORYSI
Sequence: MSVSAAVAAASTSRTLVLARRRSPPASRVAATSRGRPFSSGPHPLAVSPATRAPAMATDCAAAAAAAGSKKKKEVLIFDAEEDLAVSLAKYTAELSAKLAAERGAFTVVLSGGSLIKNIRKLAEPPYLDSVDWSKWHVFWVDERVVPKDHEDSNYKLALDGFLSKVPIPTGQVYAINDALSAEGAADDYETCLKQLVKNGVIAMSQSTGFPRFDVMLLGMGPDGHIASLFPGHPLVNENKKWVTYIKDSPKPPPERITFTFPVINSSAYVAMVVTGAGKAGAVQKALSDKQTSSDLLPVEMAVLQDGEFTWFTDKPAVSMLQNK
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
Probable 6-phosphogluconolactonase 4, chloroplastic, 6PGL 4.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NOC_LYSSC
Sequence: MKSPFSRFFGGGSKTEPIVKNEVEQAEAVHTAEEVIKLPIDQIVPNRFQPRTIFDDEKIEELSRTIHTHGVIQPIVVRKTSENQYEIIAGERRYRAMKKLQWTEVPAIVRNLTDKETASIALIENLQREELTAIEEAVAYQKLLELHELTQEALAQRLGKGQSTVANKLRLLRLPDEVQQAILQRKISERHARALIAIKDQPLQLEVLQQTVDNDWNVRQLEEQIQAILHPVTDEQESVPKKAKPKRKAISKDVRIALNTIKQSLTMVTKSGITVKTEEEDTEEYYQITVKIPKKKKV
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: THIO_STAAN
Sequence: MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: F16PA_CAUSK
Sequence: MTTLTDLAGWLAMEPAGDDVKAVVTVIAGACAQISKVVASGAISGSLGAAGQVNVQDEEQKKLDIITNDILRGALKACGPVAGLASEELEEIETTGREGGFLVTFDPLDGSSNIDVNVSVGTIFSILPAPATGIPTEADFLQPGRQQVAAGYAVYGPQTMLVLTLSKGVAGFTLDADGAWRLTHGDVAIPADTAEFAINMSNQRHWAQPVRRYIDGCLQGKSGPRGKNFNMRWVASMVADVHRIAMRGGIFMYPWDAREPDKPGKLRLLYEANPMSLIVERAGGKSTLDGVTAILDVQPTKLHQRVPVVLGSANEVDQVAAG
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S1_CANGA
Sequence: MPPSTELDALVDKIVNDHSLSEPGQSLKELGDNGKYIMDVQMKKLLKLHDQSFIERCFTPMEELKNRYAKVKERSGDLQKEAELVDRDIRIIEMAIQDINKNKSHQ
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: WDR35_HUMAN
Sequence: MFFYLSKKISIPNNVKLQCVSWNKEQGFIACGGEDGLLKVLKLETQTDDAKLRGLAAPSNLSMNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLIIVWMLYKGSWIEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLSHVTWSADSKVLLFGMANGEIHIYDNQGNFMIKMKLSCLVNVTGAISIAGIHWYHGTEGYVEPDCPCLAVCFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHMGSVLAVAGFQKAAMQDKDVNIVQFYTPFGEHLGTLKVPGKEISALSWEGGGLKIALAVDSFIYFANIRPNYKWGYCSNTVVYAYTRPDRPEYCVVFWDTKNNEKYVKYVKGLISITTCGDFCILATKADENHPQEENEMETFGATFVLVLCNSIGTPLDPKYIDIVPLFVAMTKTHVIAASKEAFYTWQYRVAKKLTALEINQITRSRKEGRERIYHVDDTPSGSMDGVLDYSKTIQGTRDPICAITASDKILIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARVTDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYICNFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHPRLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFVKRLGKLLSESMKQAEVVGYFGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYFADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPENHKLLPEIAQMFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNKTLDAIELYRKANYFFDAAKLMFKIADEEAKKGSKPLRVKKLYVLSALLIEQYHEQMKNAQRGKVKGKSSEATSALAGLLEEEVLSTTDRFTDNAWRGAEAYHFFILAQRQLYEGCVDTALKTALHLKDYEDIIPPVEIYSLLALCACASRAFGTCSKAFIKLKSLETLSSEQKQQYEDLALEIFTKHTSKDNRKPELDSLMEGGEGKLPTCVATGSPITEYQFWMCSVCKHGVLAQEISHYSFCPLCHSPVG
What is the function of this protein?
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking (PubMed:21473986, PubMed:28400947, PubMed:29220510).  May promote CASP3 activation and TNF-stimulated apoptosis.
What are the official names of this protein?
WD repeat-containing protein 35, Intraflagellar transport protein 121 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Protein: YL21A_YEAST
Sequence: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTKVGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty2 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty2-LR1 Gag polyprotein, TY2A, TYA, Transposon Ty2 protein A.
What are the subcellular locations of this protein?
Cytoplasm.