PharMolix/UniProtQA huggingface dataset:
Protein: CITD_STRP3
Sequence: MDIKQTAVSGSLESSDLMITVSPNDEKTITITLDSSVEKQFGNHIRQLIHQTLVNLKVTTAKVEAVDKGALDCTIQARTIAAVHRAAGVDQYDWKEIDSWNV
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_YERPY
Sequence: MIKQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRDIDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGVYSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILLLIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVTKNHITLYILAFMVATLMLTLSGYAGYKYLVVAAAVSVWWLGMALRGYKATNDSVWARKLFVFSIIAITSLSVMMSVDFNVHSSAVLLTYAG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLB_CHLPN
Sequence: MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYLEVTSLIEEIANTKPYALIEHLANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKFTISKELCPSPVLSA
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
What are the official names of this protein?
Probable dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin aldolase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: CLC4E_MOUSE
Sequence: MNSTKSPASHHTERGCFKNSQVLSWTIAGASILFLSGCFITRCVVTYRSSQISGQNLQPHRNIKELSCYSEASGSVKNCCPLNWKHYQSSCYFFSTTTLTWSSSLKNCSDMGAHLVVIDTQEEQEFLFRTKPKRKEFYIGLTDQVVEGQWQWVDDTPFTESLSFWDAGEPNNIVLVEDCATIRDSSNSRKNWNDIPCFYSMPWICEMPEISPLD
What is the function of this protein?
Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: recognizes damage-associated molecular patterns (DAMPs) of abnormal self and pathogen-associated molecular patterns (PAMPs) of bacteria and fungi (PubMed:18509109, PubMed:18490740, PubMed:18776906, PubMed:20008526, PubMed:19171887, PubMed:23602766).  The PAMPs notably include mycobacterial trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid with potent adjuvant immunomodulatory functions (PubMed:20008526, PubMed:23602766).  Interacts with signaling adapter Fc receptor gamma chain/FCER1G to form a functional complex in myeloid cells (PubMed:23602766, PubMed:18776906).  Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 (Th1) and T-helper 17 (Th17) cell subtypes (PubMed:23602766).  Also recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia and mediates macrophage activation (PubMed:19171887).  Through recognition of DAMPs released upon nonhomeostatic cell death, enables immune sensing of damaged self and promotes inflammatory cell infiltration into the damaged tissue (PubMed:18776906).
What are the official names of this protein?
C-type lectin domain family 4 member E, C-type lectin superfamily member 9, Macrophage-inducible C-type lectin, Mincle.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cell projection, phagocytic cup.
Protein: CYSG_ACTSZ
Sequence: MHYFPVFADLNNRPVLVVGGGGVAARKVNLLLKANADVRIVAQKLNAELTALFELGHILWIAGEFNSEQIRNVFLVIAATDDEYLNERVFRVAESQQKLVNVVDDQARCSFIFPSIIDRNPIQVAVSSGGTAPVLARLLREKLEALLPQHLGAMADISGKWRHKVKTKLKTVTERRRFWESLFNGRFSQLLKNRQTEAAKKELELQLDKDYRGGFVSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDEILELVRRDAKLVFVGKRAQGKQVAQENTNALLVKYAQQGKRVVRLKGGDPFVFGRGGEELEVLAERQIPFSVVPGITAAIGATAYAGIPLTHRDYAQSAVFVTGHRKANASDIEWQTLARSNQTLVIYMGTLKAKDIAERLQQFGRAGSTPIAVISQGTQARQKTHIGTLTALAEIAENAPTPALIVVGEVVTLHDKLAWFGEQKFAQKRPHFTLDSLRIESVA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: NRDIL_STRPN
Sequence: MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLVKEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGSGNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN
What are the official names of this protein?
Putative NrdI-like protein.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: GCSPB_LISIN
Sequence: MNLEETMPLVFERSIPGRIGFSLPESDVPETNAGDYFDEAYLRSTPADLPELSELEIMRHYTNLSNHNFGVDSGFYPLGSCTMKYNPKINEKVARFPGFANIHPNQPESSVQGALELLYDLQTSLVEITGMDEVTLQPAAGAHGEWTGLMLIRAFHEKNGDTKRTKVIIPDSAHGTNPASAAVAGFDVVTVKSNEKGLVDVADLKKVVGEDTAALMLTNPNTLGLFEKDIVEMAEIVHAAGGKLYYDGANLNAIMAKVRPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPIGVKKELIPFLPTPVLTKKDDAYTFDYNYPDSIGRVKPYYGNFGINVRAYTYIRTMGPDGLKLVTEYAVLNANYMMRKLQDAYDLPFDQVCKHEFVLSGNRQKKLGVRTVDIAKRLLDHNFHPPTVYFPLIVGEAIMIEPTETESKETLDSFIDTMLKIAKEAEENPEIVQEAPHSTYVKRLDETRAARKPVLRYQKEV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: RS10_RHOPB
Sequence: MNGQNIRIRLKAFDHRILDSSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CBIA_METTH
Sequence: MRVVLAGTGSAVGKTTIATGIMKALSGRGVQPFKVGPDYIDPSYHTMATGNTSRNIDSFFMTEAQIREAFTRAMKLSGSRMGIIEGVRGLYEGISPIGDTGSTASVAKALDAPVVLIINSRSLVKSAAAMVLGFRSLDREVKIEGVILNQVKNRRHYLKTRRAVEELTGTAVIGGIPRSSELEVEQRHLGLVPAVERDTIAAQIEKWGLAMEEYIDLEALQDIMSSAGKIRGERQPLWQRGNRKRVRIGVAIDEAFNFYYQENIEALEDNAASVVPFSPIHDEELPDVDAVYIGGGYPEIFAAELESNTSMRKSIQRFHADGRPIFGECGGLMYLMSSIDEREMCGVFPHPAEMTGRVQGLSYVIAEAVMDNLITEAGDKFRGHEFHYSRVLGASGGKFAFRVLRGRGIVDSLDGITSGSSLASYIHIHAASCPQFAANFTRNAWEF
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase, Ni-sirohydrochlorin a,c-diamide synthase, Ni-sirohydrochlorin a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: GATB_BORDL
Sequence: MEYKLLIGLEVHVQLGLKTKAFCGCKNDFGGIPNSRVCPICLGLPGALPSVNKELVSSAILAGHATNSTIRNIVKFDRKHYAYPDLPKGYQISQNDEPICENGFIFIKTSLGVKRINIARIHMEEDSGKSLHLLSNDNQSYIDFNRAGAPLLEIVSQPDIRSGEEAVAYLNALREIFRYLDLSECSMENGSFRCDVNINLLINENDVNYKTPISEIKNLNSFKSVKLAIDYEESKQKEEWILYRKTLESVGKCTMGFDDKKGITVLQRSKETISDYRYIKDPDLPLIKLESDYIENIKSHRMVELPFDARIRLQEQYGLSDFDVVTLTSDKNLVKYFEEAALTSSEPKKVANWILSEVLSVLNEREIGILDFNLPASYIGELVEFILNGKISGKISKEIFLEMVDRNVSSITIINEKKLEQISDKSFIESIVIEVLNENPKSIELYKKGKSHAVKFMMGQIMRKTSGKVNPVLSNEILMNKLQDV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PAC1_PSES3
Sequence: MNAPVPVPRVADFTCEKKPASGSRGMVVTNHPLASAAGAQILLAGGNAIDAAVASLFALTVAEPMMVGILGGGLSHIRLADGRHVVIDNLSTAPGKATAEMYECLSDEIGKQRDTRDRQNVVGAKAVAVPGALKGWCEALARFGTLPLAEVLQPAIGLAERGFVVTPYLSNCITDNAGDLARDPGLAAMLLPGGKPLQPGMRLVQSDYAASLKLIAAEGPDALYGGKLGRALTDYMAANGGLIDQADLANYRIELREPIRGSYRGYEIIGPPPPSSSGVHITQMLNILEGYDIGSLGFGSTDAVHLLAEALKIAFADRAVATADPAFVKVPVARLIDKAYADERRALIEMEQAKSWTAGLSGGESADTTHVTVADAMGNVVSATQTINGLFGACVQIPGTGMIANNYMYNFDPHPGRALSIAPGKRVFTSMAPMMALKEGRIAFALGLPGALRIFPSALQAIVNLIDHRMSLQEAVEAPRVWTEGGVLELEEAIPEAVAQALIARGHKVVRSPRVAGGMNAIAFNPDGTLTGAACWRADGTPVAISGGLARAGARFTI
What is the function of this protein?
Besides the cephalosporin acylase I activity which converts GL-7ACA into 7-ACA; this enzyme displays some gamma glutamyltranspeptidase activity.
What are the official names of this protein?
Acylase ACY 1 proenzyme.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
Protein: NORM_NEIMA
Sequence: MLLDLNRFSFSVFLKEVRLLTALALPMLLAQVAQVGIGFVDTVMAGGAGKEDLAAVALGSSAFATVYITFMGIMAALNPMIAQLYGAGKTDEVGETGRQGIWFGLFLGVFGMVLMWAAITPFRNWLTLSDYVEGTMAQYMLFTSLAMPAAMVHRALHAYASSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPALGGAGCGLATMAVFWFSALALWIYIAKENFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLSYFLEASAFSFIVFLIAPFGEDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRREFSRARYISGVSLVSGWMLAVITVLSLVLFRSPLVSMYNNDPAVLSIAATVLLFAGLFQPADFTQCIASYALRGYKVTKVPMFIHAAAFWGCGLLPGYLLAYRFDMGIYGFWTALIASLTIAAIALVWCLELCSREMVRSHKAV
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRS23_MACMU
Sequence: MAGIPGLLFLLFLLLCAVGQVSPYSAPWKPTWPAYRLPVVLPQSTLSLAKPDFGAEAKLEVSSSCGPQCHKGTPLPTYEEAKQYLSYETLYANGSRTETQVGIYILSSSGGGAQHRDSGSSGKSRRKRQIYGYDSRFSIFGKDFLLNYPFSTSVKLSTGCTGTLVAEKHVLTAAHCIHDGKTYVKGTQKLRVGFLKPKFKDGGRGANDSTSAMPEKMKFQWIRVKRTHVPKGWIKGNANDIGMDYDYALLELKKPHKRKFMKIGVSPPAKQLPGGRIHFSGYDNDRPGNLVYRFCDVKDETYDLLYQQCDAQPGASGSGVYVRMWKRQQQKWERKIIGIFSGHQWVDMNGSPQDFNVAVRITPLKYAQICYWIKGNYLDCREG
What are the official names of this protein?
Serine protease 23.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1182_METJA
Sequence: MQVCIIGAGLSGSILYRLLSEDGFYINIYDHVLVRGCKSMNFIFSNKNEILTVKKVLKTVNINIKDYIIREIKEVNIGGDNYYPNKKIYVINKSKLIEDLVPRTVVTNREFNPVIRRYTTKVIDTGVIVREFNTEAETKFYDLVVDASGCAKVLQLGNVYDKYKNDIKTCQFLIAYENEESPEKFDKFFIDEIKIHKGKPMIGYTWITPIDDGLYHVGCAYYKNDHELWTYLTKYTKKMFGSDYVRVCGCTSKINGNLISESFIGGIYEKRCVAGVGESIGLTTPLGHGNIYAIISAYILSRFIKKYDLNEAVLKYKDYIPKKFAELDKEKKAVRNFNVLRITKLLRDYYNIPAHESMKIILKSLY
What are the official names of this protein?
Uncharacterized protein MJ1182.
Protein: RL30_GEOSW
Sequence: MAKKLEITLTRSVIGRPEDQRITVKTLGLRKMHQTVVHNDNPAIRGMINKVAHLVKVKEIEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RNMT_MYCBO
Sequence: MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIRN
What is the function of this protein?
Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).
What are the official names of this protein?
Rhamnosyl O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the rhamnosyl O-methyltransferase family.
Protein: PANB2_ORYSJ
Sequence: MSFSRLLTPRILLDTTAVFPPSSSVVAPSLSRQLRCTRTGGSPPAPPHRLVARRAMSNGAAEPAIYGGGGGAQQAASSAAARRVTLATLRGKHRRGEPISMVTAYDYPSGVHVDAAGFDICLVGDSAAMVAHGHDNTLPISLDLMIEHCRAVARGAARTFLVGDLPFGSYEASTAQAVGSAVRVMKEGGVNSIKLEGSAPSRISAARAIVDAGIAVMGHIGLTPQSVSALGGFRPQGKTVESAVKVVEAALALQEAGCFAVVLECVPAPVAAAATSALTIPTIGIGAGPFCSGQVLVYHDLLGTFQTSHAKVSPKFCKQYGNIGDVINRALSKYKQEVETQSFPGPSHTPYKLAATDVDAFLNALKMKGLNVAADAAADAVEYTDEKEINGTPQLKVYA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 2, mitochondrial, Ketopantoate hydroxymethyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SLYX_SHEPA
Sequence: MDNLENRVEELEMKIAFQDGTIEELNTQVIKLNNLLASQQDQLRILLSKLHAVEPSNMASQSEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RL32_PSEE4
Sequence: MAVQQNKKSRSARDMRRSHDALSENALSVEKTTGEVHLRHHVSPEGVYRGRKVIDKGADE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLGS_ECO81
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQTRELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.
Protein: DER_BUCAP
Sequence: MLPIIVLIGRTNVGKSTLFNILSKTRNALVADYPGLTRDRNYGYCYLKENKKITIVDTAGINFKSQKIEKQSHEQTLKAIKECDGILFLVNARDGVMPEEYEISRKIRKYEKKTILVINKIDGIKEISKINEFYSLGFKENIKISASHNQGINNLISKYLTPWINSKFKEKKLEKISQEHSKKEKNSVKIACIGKPNVGKSTLINSLLMKKRMITSNKAGTTLDTVLVPIKYNYKNYIFIDTAGMSKKKSKTNKIEKFCKIKTLQTIEKSHLTLLIIDAKDQISKQDLLLSSFIEKSGKPLIIVINKCDLLSLKEKKNLENLIKKQLKCNFFSKIHFISALNNEGTVELFKSIDTSYHTSQKKIKTSQVMKIMHKAVKKHQPPIINGRRIKLKYAHLGNSNPIEIMIHGNQVKNLSLCYKKYLKNFFYKTLKMNGTPIKIQFKETMNPYISKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: G1PDH_THESM
Sequence: MVMFMHLMELPREVLLGEDLKDKVSQVAKRLKLGENVLILYGPKTKEIAGKDIEKHLKEFFHVKNLLIKEASMKNVQKALEIIRNENIDWLLGVGGGSIIDVAKLASFKADVPFISFPTTASHDGIASANASIRDLGAKTSIKARPPVAVIADVNIIKTAPYRYLAAGVGDMVSNLTAVKDWELAHRIRGEYFSEYAASLSLMSAKMVIKNADIIRLSNEESVRKVIKALISSGVAMSIAGSSRPASGAEHLFSHALDAIAPKPALHGEQCGVGTIIMAYLHGLNWKKIRETLKRVGAPTNAYELEIDPGFIIEALTIAHTIRPERYTILGKDGLTKEAAEKAAKITGVI
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_SHEON
Sequence: MESTDKLTDTNAILAYLYETFPLCFIAEGETKPLKIGLFQDLAERLADDSKVSKTQLRVALRRYTSSWRYLKSVKAGAQRVDLDGQPCGELEQEHIDHAQAMLKESQEKAKAKRAAQTPKAAPAGKAPAKKAPKKVAVPARKTERPAKAAPKVEPVVNLVQAQLTDLAKKQRVNVKLGMTPVAGVITDINKEDIHVQLDSGLTIKVKAEHILL
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_THET2
Sequence: MIQGVIQKIAGPAVIAKGMLGARMYDICKVGEEGLVGEIIRLDGDTAFVQVYEDTSGLKVGEPVVSTGLPLAVELGPGMLNGIYDGIQRPLERIREKTGIYITRGVVVHALDREKKWAWTPMVKPGDEVRGGMVLGTVPEFSFTHKILVPPDVRGRVKEVKPAGEYTVEEPVVVLEDGTELKMYHTWPVRRARPVQRKLDPNTPFLTGMRILDVLFPVAMGGTAAIPGPFGSGKTVTQQSLAKWSNADVVVYVGCGERGNEMTDVLVEFPELTDPKTGGPLMHRTVLIANTSNMPVAAREASIYVGVTIAEYFRDQGFSVALMADSTSRWAEALREISSRLEEMPAEEGYPPYLAARLAAFYERAGKVITLGGEEGAVTIVGAVSPPGGDMSEPVTQSTLRIVGAFWRLDASLAFRRHFPAINWNGSYSLFTSALDPWYRENVAEDYPELRDAISELLQREAGLQEIVQLVGPDALQDAERLVIEVGRIIREDFLQQNAFHEVDAYCSMRKAYGIMKMILAFYKEAEAAIKRGVSIDEILQLPVVERIGRARYVSEEEFPAYFEEAMKEIQGAFKALA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RS6_SACEN
Sequence: MRHYELMVILDPSLDERTVAPSLENFLNVIRNDGGSVEKVDVWGRRRLAYEIDKQAEGIYVVLDLNSEPASVKELDRQLNLNETVLRTKVLRRVVEPRKAARVARAAAKAKNRPEASV
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: VE2_HPV14
Sequence: MENLSDRFNALQDQLMNIYETAANTLESQIEHWQTLRKEAVLLYFARQNGVTRLGYQVVPTLAISEAKAKQAIGMVLQLQSLQKSQFGSEPWSLVDTSGETFRSAPENHFKKGPVSVEVIYDNDKDNANAYTMWKHIYYQDDDEQWHKSASGVNHTGIYYMQGTFRNYYVLFADDATRYSKTGHWEVKVNKETVFTPVTSSTPPESPGGQADSNTSSKTPTTATDSTSRLSPADSRKQSQQANTKGRRYGRRPSSRTRRTTETRQRRRSRSKSRSRSRSRSRLRSRSRSQSSERRSRYRSRSRSRQKEVSRITTTTRGRGRGSSSTSSKRSQRARGRGRGGSRGRRSSSTSPTSSKRSRRESESSRQRGISPSDVGKSLQSVSSRNTGRLGRLLDEALDPPVILVRGDPNTLRCFRNRAKQKFTGLYRAFSTAWSWVAGDGTERLGRSRMLISFFSFNQRRDFDQTVKYPKGVDRSFGSFDSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CRCB_SHESA
Sequence: MNNLLLVALGGSIGAVFRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHISPELKALIGVGLLGALTTFSTFSNETLLLMQEGDWLKAALNVVLNLSLCLFMVYLGQQLVFSRI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SFRP5_MOUSE
Sequence: MWVAWSARTAALALLLGALHGAPTRGQEYDYYGWQAEPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDTQVFLCSLFAPVCLDRPIYPCRSLCEAARAGCAPLMEAYGFPWPEMLHCHKFPLDNDLCIAVQFGHLPATAPPVTKICAQCEMEHSADGLMEQMCSSDFVVKMRIKEIKIDNGDRKLIGAQKKKKLLKAGPLKRKDTKKLVLHMKNGASCPCPQLDNLTGSFLVMGRKVEGQLLLTAVYRWDKKNKEMKFAVKFMFSYPCSLYYPFFYGAAEPH
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types.  SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
What are the official names of this protein?
Secreted frizzled-related protein 5, sFRP-5.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GARD_ECOLI
Sequence: MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
What is the function of this protein?
Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).
What are the official names of this protein?
Galactarate dehydratase (L-threo-forming), GalcD.
What is the protein family that this protein belongs to?
Belongs to the UxaA family.
Protein: RL24_BIFA0
Sequence: MVAKIKSGDLVKVIRGKDRGKEGTVKRVLKDDRLIVEGVQIVKKHVRATQQGQQAGIVSVEAPIHRSNVMVIDPETKQPTRVGVVIKEEARDGKVKTVRVRVAKKSGKELA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RHO_SALTY
Sequence: MNLTELKNTPVSELITLGESMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNYDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMMKRS
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.