PharMolix/UniProtQA huggingface dataset:
Protein: PSBM_OENEH
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYD_CLONN
Sequence: MAESLNGLKRTVMCGELRESHIGQKHVVMGWVQRKRNLGGLVFVDLRDREGILQVVFGEEINKEAFEKADLVKPEYCIAVEGELVRRESPNEAMPTGMVELKGQNIKILSESETPPIYIKEDLDTDEAVRLKYRYLDLRRPDMQKIFKVRHKTAKVIRDFLDENGFLEMETPMLTKSTPEGARDYLVPSRNYPGMFYALPQSPQLFKQLLMVSGYDKYFQITKCFRDEDLRANRQPEFTQVDMELSFVDMEDVIALNEKLIQKVFKEVANVDVQLPIQRITYKEAMDKYGSDKPDLRFGMEINDITDAVKDVDFKVFKDAIENGGSVRAIKAPNCATMGRKQIDKLGEFVKTYKAKGLAWIAYKEDEIKSPIAKFLGEEGINKVIESLDAKVGDLILIVADKDSVVLQSLGALRLEMAKRLEILKDNKEFRFAWVTEFPLLSYNEEEDRYQAEHHPFTMPMDEDIEYLESDPGRVRAKAYDIVLNGEELGGGSIRIHDTKLQEKMFNVLGFTSESAWERFGFLLEAFKFGPPPHGGLAYGFDRMIMFLAGTENIKDVIAFPKNQNAYCPLTEAPNVVDEKQLGELGIGVQKQK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULK2_HUMAN
Sequence: MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQGPVKKSCPVPVPMYSGSVSGSSCGSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSCDMPVGTAGRRASNEFLVCGGQCQPTVSPHSETAPIPVPTQIRNYQRIEQNLTSTASSGTNVHGSPRSAVVRRSNTSPMGFLRPGSCSPVPADTAQTVGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHDSRSRNSSGSPVPQAQSPQSLLSGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHTGAGYSYSPQPSRPGSLGTSPTKHLGSSPRSSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAEEQSKDGNEPRECAHCLLVQGSERQRAEQQSKAVFGRSVSTGKLSDQQGKTPICRHQGSTDSLNTERPMDIAPAGACGGVLAPPAGTAASSKAVLFTVGSPPHSAAAPTCTHMFLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDLTAMRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQIKSGKLSPSTAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSRILQDPADIENVHKYKCSIERRLSALCHSTATV
What is the function of this protein?
Serine/threonine-protein kinase involved in autophagy in response to starvation.  Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes.  Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR.  Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1.  May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences.  Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration.  Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.
What are the official names of this protein?
Serine/threonine-protein kinase ULK2, Unc-51-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Localizes to pre-autophagosomal membrane.
Protein: SRY_APOAG
Sequence: PMNAFMVWSCGERRKLAQQNPSMQNTEISKQLGYRWKSLTEAEKRPFFQEAQRLKTL
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: KOJT_ASPOR
Sequence: MQSFRQYRRMRRDLQESIKLHGPYAAAGDRHVQPTDDILEDADDARLEKGIHSMNGHGQSPYSTPGIVLHDGQRVTVPGVNLRRASEICERVNTKTLFIVGFDGPDDQLNPKNWSIGRKWATLGIVGTTGMLVGWASSIDSTVIKQGQEAFGVSEVAESLATALFLFAFGFGSLVAAPFSETVGRNPVYIATLSILMIFTMASGLAPNFGAQLAFRFLAGLFGCTPMTTFGGSMADIFDPMDRTYAFPVCCTLSFLGPFLAPMVGAFIGQSTHISWRWTEWCTLIMAALVTGAIFLFVPETYGPVLLQWKAKQLREITGDPRFMAEIELRQTSLVTRLMHSCSRPFHLFFREIMVALFTMYLVVVYIVLFGFLTGYEFIFGRTYGFTQGSVGLTFIGMNIGFLIAFAMVPHIYFSYKKRLQNAIENGHNGLPPEERLWFAMYGAPWLPISLFWMGWTSYPSISYWSPLVASVAFGFSVQGIFISTYQYLIDTYELFAASALVSATFFRYIAAGAMVIVSIPMYGNLGVHWSLTLLGCISVLMTPVPYIFYKYGHVIRQRNKKTP
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent (PubMed:20849972, PubMed:35034313).  Involved in the seretion of kojic acid (PubMed:20849972).
What are the official names of this protein?
MFS-type transporter kojT, Kojic acid biosynthesis cluster protein T, Kojic acid transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS4_SALAI
Sequence: MSLTLLPAVDVADGQAVRLVQGAAGSETAYGDPLDAALAWQRDGAEWIHLVDLDAAFGRGSNADLLADVVRQLDVRVELSGGVRDDESLRAALATGATRVNIGTAALEDPLWCDRVCGEYGDRVAIGLDVRGRTLSARGWTRDGGDLWEVLERLDRAGASRYVVTDITKDGTMRGPNLELLREVCARTNAPVIASGGVSTLADLRALAALEPAGVEGVIAGKALYAGAFTVAEALRTLADA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_GEOSM
Sequence: MADLESYFKDLMDGKRAGWKDRLALAGLRLASLPYALALRFRALGYASGIIPSHRLPRPVISVGNVTLGGTGKTPTVAWIASYLIGRGKRVAVLSRGYGGSAEGRLRIVSDGNNLLVGPEEAGDEPCLLARKVPGLMVVTGADRYRAGVLALKKLNPDVFILDDGFQHLKLKRDLNLLLLDCRRPFGNERVLPAGYLREPKGAIERADLVLFTRCQPESAPQLADLAKPACRSLHRLNGCVPLQGGEPLAFSDLKGERCMAFAGIADPAGFFDGLEKEGVQLVTTLAFSDHICYGDAEIAAVLRLKKASRSAFMVTTEKDAVKLAPFMDQLGTVYVAQLDLELLDAPLLQEMLDRLLTAGKARPLQPENDGNKRA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: UVRC_BACC2
Sequence: MHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIVDFEYIVTSSNLEALILELNLIKKYDPKYNIQLKDDKTYPFIKITAEKQPRLLITRNVKKDKGKYFGPYPNAQSAHETKKLLDRMYPLRKCTNMPDKVCLYYHMDQCLAPCVKEVTEEQNKEIVDEIIKFLNGGHKEVRSELEIKMYEASEKLEFERAKELRDQIAHIDAIMEKQKMIMSDLVDRDVFGYAVDKGWMCVQVFFVRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYENSSHFKPKEIVVPGSIDSELVERFLEVEATQPKRGKKKDLVELANKNAKIALEEKFYLIERDEERTIKAVDHLGKQLGIETPYRIEAFDNSNIQGTNPVSAMIAFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKENLPLPDLIIIDGGKGHLAAASDILEDELGLYIPMAGLVKDDKHKTSHLIIGDPPEPVVLERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDDIPGIGDKRKKVLLKHFGSLKKMKEASVAEFVEAGMPKNVAETIYTYLTDKKTL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_PARPJ
Sequence: MTTALDQLKQYTTVVADTGDFQQLAQYKPQDATTNPSLILKAVQKDDYKPLLEKTVKAHASKPVGAIIDQLLIAFGTEILKIIPGRVSTEVDARLSFDTEASIAKGRELIALYKEHGIGRERVLIKLASTWEGVRAAEVLQKEGIHCNMTLLFSLAQAAACAEAGAQLISPFVGRIYDWYKKNAGSAWDEAKDGGANDPGVKSVRRIYAYYKKFGYKTEVMGASFRTPGQILELAGCDLLTISPDLLQKLQESTEKVERKLSPDSAKDADIERVPVDEASFRFLVNDEAMATEKLAEGIRAFAADAVKLEKLIEALR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_NITEU
Sequence: MAKKIVGYIKLQIPAGKANPSPPVGPALGQRQLNIMEFCKAFNAATQKMEPGLPVPVVITAYADKSFTFILKTTPASVLIKKLAGLSKGSAQPHVDKVGKLTRSQAEEIAKIKMADLTAADMDAAVRTIAGSARSMGVEVDGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SGO1_ARATH
Sequence: MVRATVLNVGDHASEGVRTNKAKGEKMVLEPPMNSAQRRKLGDITNLQNQKNLMNQGAKHQQQAILISSKENAENLQKENTKLMKVVMERDGIKSDLKKLRIEFQKVQEQNLLLAQANTRILAEFNTSKDQLKVLQHELGCKNGLVMARKMLLKEQTLPCTRHASKVKAQANACGGACKTFQPNDADHEHASGSSNANSLQRNEKANSKRRVSGRKNPANSEVLDIIGRSGETCQMEDNIDNKKLVSDSDNDAENHINDNVQSKRYCAGRQSSSSKTREASQTETLQKVVDAKEIKGDARFSLTKHSDWLKSQEPEPSESLYESRFPLRRRSARLKSQEPEPSESFHDSIETTKRRRSAIRSAMFNIQELGVIQNLNGLPDDQEIAAKARCSAREQSTGSKPEAVEPHDTKEIIGKSRISLRRQSARFNFQELGVTENLNGPHDDQTIAANARCCASEQSIGSKPEAVEPHDIEERIGKIRVSSRRQSANIETPRAIKEPANPPLHDDNVEESSQISCSVSMELKRESKKKPTGDESEEMRKTTVGRPSRQAAEKIKSYKEPSLKEKMRGGF
What is the function of this protein?
Protects sister chromatid centromere cohesion in meiosis I but not through the protection of the cohesin SYN1 (PubMed:23884434).  Required with SGO2 for full protection of centromeric cohesion during anaphase I (PubMed:24206843).  Required to prevent precocious release of pericentromeric cohesins during meiosis (PubMed:24206843).  Not necessary for the maintenance of the synaptonemal complex (SC) (PubMed:23884434).  Not required for monopolar spindle orientation in meiosis I (PubMed:24506176).
What are the official names of this protein?
SHUGOSHIN 1, AtSGO1.
What is the protein family that this protein belongs to?
Belongs to the shugoshin family.
Protein: CYB_ELIMA
Sequence: MTNIRKSHPLLKIINHSFIDLPTPSNISSWWNFGSLLGICLILQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGMYYGSYMSIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIVALVMVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDILGVLLLFLFLISLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALIPHLHTSKLQSLMFRPLTQALYWILVADLLILTWIGGQPVEYPFIIIGQLASVLYFAIILIFMPMAGMIEDSILKMD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL5_YERPN
Sequence: MAKLHDYYKDEVVKQLMSQFGYDSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPFITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDDEGRALLAAFKFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NDNF_MOUSE
Sequence: MELFYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKEFFHDSSVIPDGAEVSSYLFRDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELHEGSSADGSGDPELLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSFGRTTVTLAWKPSPTASILKQPIEYCVVINKEHNFKSLCAAETKMNADDAFMVAPKPGLDFNPFDFAHFGFPTDNLGKDRSLLAKPSPKVGRHVYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNTNMSTAYVGAFVRTKEEAKQKTVELKDGRVTDVFVKRKGKKFLRFAPVSSHQKVTFFIHSCMDAVQVQVRRDGRLLLSQNVEGIRQFQLRGKPKGKYLIRLKGNRKGASKLKILATTRPSKHAFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVDGNYSEDQKRREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKIVKTRKVC
What is the function of this protein?
Secretory protein that plays a role in various cellular processes.  Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645).  Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:31883645).  May also act through the regulation of growth factors activity and downstream signaling (By similarity).  Also regulates extracellular matrix assembly and cell adhesiveness (PubMed:18757743).  Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764).
What are the official names of this protein?
Protein NDNF, Epidermacan, Neuron-derived neurotrophic factor.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1354_MYCTO
Sequence: MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYLVEQLGVDVSFLRHNDRDRRATRLVAEWPPRLNIPDPDPLRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAAAVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIATLFAQVQARVAAEARLRYLADHDDLTGLHNRRALLQHLDQRLAPGQPGPVAALFLDLDRLKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPMSADAAQPLAERLRDQLKDHVAIGGEVLTRTVSIGVASGTPGQHTPSDLLRRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRLVYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIPVAESINLAGELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADTIGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGYSAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVAEGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPATDPALS
What are the official names of this protein?
Uncharacterized protein MT1397.
Protein: YLL53_YEAS8
Sequence: MWFPQIIAGMAAGGAASAMTPGKVLFTNALGLGCSRSRGLFLEMFGTAVLCLTVLMTAVEKRETNFMAALPIGISLFMAHMALTGYTGTGVNPARSLGAAVAARYFPHYHWIYWISPLLGAFLAWSVWQLLQILDYTTYVNAEKAAGQKKED
What are the official names of this protein?
Putative uncharacterized protein EC1118_1L10_0100g.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLPP_SOLBU
Sequence: MPIGVPKVLFRNPGDPISSWVDVYNRLYRERLLFLGQGISTDLSNQLIGLMMYLSMEDENKELYLFVNSPGGWVIPGIAIYDTMQFVRPDIHTICIGLAASMGSFILAGGQLTKRIAFPHARVMIHEPYSAFYMAQVGEFVMEAVELMKLRETLTRVYAERTGKPFWVVHEDMERDIFMSATEAQAYGIVDFVAVQGK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y2696_SYNJA
Sequence: MDTRLINIGFGNIVAAGRVIAIVSPESAPIKRIISDARERGQLVDATYGRRTRAVIITDSGHVILSAIQPETVANRFLTAKVGAPEEPE
What are the official names of this protein?
Putative regulatory protein CYA_2696.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: AROC_NITHX
Sequence: MSHNTFGHLFRVTTFGESHGVAIGCVVDGCPPQLALTVEEIQRDLDRRRPGQSRFTTQRQEADQVKILSGVMETASGQVTTGAPIALLIENTDQRSKDYSEIKDKFRPGHADFTYEAKYGLRDYRGGGRSSARETATRVAAGAIARKIVPGVTVRGALVQMGPHRIDREKWDWNEIARNPFFCPDKDKAAFFESYLDGIRKSGSSIGAVIEVVAEGVPAGLGAPIYAKLDGDLAAALMSINAVKGVEIGAGFGAAELSGEDNADEMRSSSSNMGNNGPVFLSNHAGGILGGISTGQPVVARFAVKPTSSILSPRKTVDRNGADTDIFTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQVGPR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: AR274_ARTOA
Sequence: MAPRIPSIPSSTDLSGQSALVTGSNTGIGFENARQFLQLKASPVYLAVRSVERGQEAKKLLLDDPEVKKKNPGAVVEIYQVDMASFDSVAAFAQKFSEVKKLNIAVLNAGVSFFKYIPTSDGYETVLQVNYLSNALLATHLLPLLKAGAAASGKPSHLAFVSSNMQHMTSLKKNTIKPNENIIDWFNNRANFGMDRYNVSKLLLTGFTNELASKIDSSQVVINSMCPGLVATNFDTNSPWYLKYLMKGVRSLMARTPSEGARALTLAAITGTEGNGKYYSDGKETPSAALLLTEDGKAFQKKLWDQTLERIQQLDPTSPPPI
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of sesquiterpenyl epoxy-cyclohexenoids (SECs) such as anthrobotrisins and arthrosporols, metabolites that possess a novel hybrid carbon skeleton consisting of a polyketide-derived epoxycyclohexenol combined with a terpenoid-derived monocyclic sesquiterpenol substructure (PKS-PTS hybrid) (PubMed:28692300, PubMed:33823587).  The SEC pathway plays an important role for fungal soil colonization via decreasing fungal nematode-capturing ability (PubMed:33823587).  Within the pathway, the cytochrome P450 monooxygenase AOL_s00215g274 is involved in specific regional ketone reductions at C-4 of farnesyl epoxy-quinone (PubMed:28692300, PubMed:33823587).  The pathway begins with the biosynthesis of 6-methylsalicylic acid (6-MSA), the first precursor of the polyketide-derived epoxycyclohexenol in arthrosporols, by the polyketide synthase (PKS) AOL_s00215g283 via condensation of 1 acetate and 3 malonate units.  The 6-methylsalicylic acid decarboxylase AOL_s00215g281 then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol.  The cytochrome P450 monooxygenase AOL_s00215g282 further oxidizes m-cresol to yield toluquinol.  With the assistance of the oxidoreductase AOL_s00215g277, the polyprenyl transferase AOL_s00215g276 catalyzes the farnesylation of toluquinol to produce farnesyl hydroquinone, the hybrid precursor for biosynthesis of SECs.  Farnesyl hydroquinone undergoes epoxidation and then subsequent dehydrogenation to form farnesyl epoxy-quinone, the first and simplest SEC.  The cytochrome P450 monooxygenase AOL_s00215g278 and the FAD-dependent monooxygenase AOL_s00215g279 might be involved in the oxygenation of the phenol moiety, most likely in the epoxy formation.  The cytochrome P450 monooxygenases AOL_s00215g274 and AOL_s00215g280 are involved in specific regional ketone reductions at respectively C-4 and C-1 of farnesyl epoxy-quinone PubMed:33823587 (Probable).
What are the official names of this protein?
Short chain dehydrogenase AOL_s00215g274, Sesquiterpenyl epoxy-cyclohexenoids cluster protein AOL_s00215g274, SECs cluster protein AOL_s00215g274.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RECA_IDILO
Sequence: MSNDRQKALDAALGQIERQFGKGSIMRLGDNQTLDIDSVSTGSLGLDIALGIGGLPFGRVVEIYGPESSGKTTMTLEVIAEAQKMGKTCAFVDAEHALDPIYAEALGVNVDDLLISQPDTGEQALEICDMLVRSGAVDIVIVDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTSNIKKSNTMCIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRTGALKEGDEVVGNETRVKVVKNKVAPPFKEAHFQILYGKGISKEGELIDLGVKHKMVDKAGAWYSYNGDKIGQGKANSMKFLQDNPKIADELEGRIRELLLSKPEKRTKEIREAERAAAKEDAKSEAKADKKTEKKGNEKDDISLS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1277_CHLTE
Sequence: MPRPQKCRAIAQDPEYRVFGPFCVGKREDEALVMSFDEFEAIRLADVEGLYQEEAARQMQISRQTFGNILASARKKLGEMLVLGKMLNVKGGNIMISQEERIFGCAACGHQWSLPYGIARPVECPSCSSQNIHRMSPGGGFGGGRRGGGKCRGFRSGLDRGPGHGEGRCQGEGHGNGNGNGNGQGRMRRNQQEGGEV
What are the official names of this protein?
UPF0251 protein CT1277.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: AMPA_AGRVS
Sequence: MSMKLEISFAPSALIEAGLVLSLKEAEATLPAGAATVDPSGIFAKAAATAKFKAKAMSVLDILAPTGSQADRLIVIGAGKAADLVDHDWLRLGGVAAANLKGSEAVTVFLDADGLTITAEGVRDFAIGMLLRAYSFDDYKTKKKDDDDKAPSAVQITLVTAVADAAERLFAAEGRAVVDGVLLARNLVNLPANVLGPVEFADRAKALEALGVEVEILTETEMASLGMGALLGVAQGSVRPPRLAVMQWKGGAPEGQPIAFIGKGVVFDTGGISIKPAGGMEDMKGDMGGAAAVIGLMHTLAARKAKVNAIGILGLVENMPDGNAQRPGDIVTSMSGQTIEVINTDAEGRLVLCDALWYCNDRFKPAFMINLATLTGAILVALANLHAGLFSNDDTLAENLLKAGLSTNERLWRMPLGKDYDKLIDSKFADMKNTGGRYGGSITAAQFLKRFVGDTPWAHLDIAGTAMASPKDEINQSWASGFGVRLLDQLVRDAYEA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.