PharMolix/UniProtQA huggingface dataset:
Protein: RUNX2_MOUSE
Sequence: MLHSPHKQPQNHKCGANFLQEDCKKALAFKWLISAGHYQPPRPTESVSALTTVHAGIFKAASSIYNRGHKFYLEKKGGTMASNSLFSAVTPCQQSFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSSLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSASYQFPMVPGGDRSPSRMVPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
What is the function of this protein?
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis.  Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification.  CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters.  Inhibits KAT6B-dependent transcriptional activation (By similarity).  In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
What are the official names of this protein?
Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha A, PEBP2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPH1_ASPTN
Sequence: MSDSDDYLQDDPDDQAFDDFADVASSPPPPKRRRLQARNQTRNTTSRRNEDNSVASDSDSFVVDDDDASKTDELPSPSQASYHFADHPENEASSKYKIFVPKRNNPQENIFVTQLTQPPSPPEMIRGPRWKKPDPPPPPPPAPTKPTPKTTRGPGHEDYGDDEDLDAAIAASLASFEEENSRLSFSTAQNSPPAPVASDNAPTNTAQTESFDFLDDIPDDAFDSDLSLTPPPPAPPSNSSRPSSFMQSSNRPLGVRQTTLFNMATRNQAPQPPQGEQVFAPPEKVEAPTQHKLNQEAISTWVYPTNLGKTRDYQFNITQKGLFHNLLVALPTGLGKTFIAATIMLNWFRWTRDAQIVFVAPTKPLVAQQVSACFGVAGIPRSQTTMLTGEAAPGIRAQEWQDKRVFFMTPQTLINDLKSGIADPKRIVLLVVDEAHRATGGYAYVEVVKFLRRYNQSFRVLALTATPGSTVESVQAVIDGLEISKVEIRTEQSLDIREYVHARNTEVQTFKNSEEMVLCMDLLSKTLQPLVDQLRTLNAYWGRDPMALTAYGLTKSRQQWMLSDAGRNSSFGLKGKVNAIFTVLASLAHGIDLLKYHGITPFYRHLLHFQGNTDGQKGGKYQRQIVQDEHFKKLMNHLSPWTKNPEFIGHPKLEYLKQVVLNHFMDAGEGSAGAEGASQSTTRVMIFVHFRDSAEEVARVLKRYEPMIRPQVFVGQASAKGSDGMNQKTQLGVVQKFKQGTYNTIVATSIGEEGLDIGEVDLIVCYDSSASPIRMLQRMGRTGRKRAGNIVLLLMEGKEEESYIKAKDNYEKMQQMIASGTRFTFHDDKSPRILPPGVKPIVDKRHIDIPEENEEQALPEPKRRGRVPKKPPKKFHMPDNVITGFTKASSLAGGSKRTAQDKRKARTPTPEPVDIPALEDVILTAEQQRELEHRYCTIGDTSPEVIRTPRTDAFPRLQLVSRPTKVVKHGSLTRRMIDALQKMDKTSSDCEGRFKEVLALESRRPAEESLIHQSISRPGNKKRLRKGRSGQPEPRLPPSRVHEEKDEDLDGSQPISPEQLLSSFTDRQGPKPFSSSPRSENLELDADFEAPDLDTLLGRR
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase mph1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA_I77AA
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPIRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYVVKPHEKGINPNYLLSWKQVLAELQDIENEGKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCKDISDLKQYDSDEPKLRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: WF15B_MOUSE
Sequence: MKLLGLSLLAVTILLCCNMARPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQMRCVDPWESPE
What is the function of this protein?
Antibacterial protein which inhibits the growth of E. coli and S. aureus.
What are the official names of this protein?
WAP four-disulfide core domain protein 15B, Elafin-like protein I, Single WAP motif protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_RHOP2
Sequence: MRHGKVHRKLNRTAEHRKAMFANMCAALIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLDKRRQAISEMRDLDQVRKLFDVLAKRYADRQGGYTRIIKAGFRYGDNAPMAVIEFVDRDEDAKGKDSGPSQDGAAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DRAM2_MOUSE
Sequence: MWWFQQGLSFLPSALVIWTFATFIFSYITAITLHHVDPALPYISDTGTIPPERCLFGVMLNIAAVLGIATMYVRYKQVHALNPEENLIIKLNKAGLVLGILSCLGLSLVANFQKSTLFIVHVCGAVLAFSMGSFYMFVQTILSYQMQPKIHSKQVFWVRLLLVIWCGVSALSMMTCSSILYSSDFGPDVVQKLHWNPEDKGYVLHLVTTAAEWSMSFSFFGFFLTYIRDFQKITLRVEANLHGLTLYDTVPCPVNNERTPLLSRDFQ
What is the function of this protein?
Plays a role in the initiation of autophagy.  In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function.  Induces apoptotic cell death when coexpressed with DRAM1.
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 2, Transmembrane protein 77.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Photoreceptor inner segment. Apical cell membrane. Note=Localized to photoreceptor inner segments and to the apical surface of retinal pigment epithelial cells.
Protein: Y1201_STRP1
Sequence: MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein (By similarity).
What are the official names of this protein?
UPF0122 protein SPy_1201/M5005_Spy0916.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: PURL_BACCQ
Sequence: MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSQEAAYFAEFQQMKMETPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQILAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_HISS2
Sequence: MKSKTHLGHTARKRFGQNFLHDNNIIQNIVMAIYPQKEQFLVEIGPGLGALTEPVAEKVERLTVIELDRDLAERLRHHPFLHQKLNVIEYDAMQFNFEQLYIDENLAEKNQKLRVFGNLPYNISTPLMFHLFKYHAIIQDMHFMLQKEVVKRLCAAPNSKAYGRLTIMAQYFCQVLPVLEVPPTAFKPAPKVESAVVRLIPHKELPYPVKDLYWLNRVTTQAFNQRRKTLRNALSTLFSAEKLTALAIDLEARAENLSIADYARLANYLADNPPTEDLQSE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STRP8
Sequence: MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTPDKANFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYSTITFIIGGSLGLDSIIKKRADMLMSFGLLTLPHQLMRLVLTEQIYRAFMITKGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH603_PARUW
Sequence: MSIPKEIIFEEEAREFLLKGIKKLADVVAFTLGPKGRNVGLEKSWGAPTITNDGASIIRDIQLEDKYENMGVAMAKEVVQKIKEKCGDGTTSGALLLRSLVEAGIKNISSGASPIGIKRGMDKAVEVVVKAIEKAAIPVKTKQETRNVAVVSASGNQEIGELIAEAMEKVSNSGAITIEEGKGTETSIEVVKGMKFDRGYVSPYLCTNLEKMIVEMDHAQILLVDKKISSIHELLPVLQATAASGRELLIIAEDIDGDALSTLVVNKLRGTLKVAAVKAPGFGDRRKAMLQDIATLTAATVVSEELGISLKEIPATALGSAEKVTVTKESTTIVGGTGAQEDIAARIKQIDAEINLAQSSYDKEKLEERRAKLSGGVAVIRVGAATETEMKQKKQMFDDSLNSTKAALEEGIVPGGGVALLNASKTLGQLKLEGDEAVGAKIVLQACETPIKQIVQNTGFDGSVVLNEVLNSPANFGFNALTEKVEDLIAAGVIDPAKVIKNTLTYAASTAGIVLLSEALIADADDEEEENSTK
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_DESHD
Sequence: MINDVLKEAEDRMVKAVEALKREYATIRAGRANPNMLDKITVEYYGTQTPVNQLANISVPEPRMLTIQPWDKSSLPMIEKAILKSDLGLNPSSDGTVIRLLIPQLTAERRTEIVKTVKKKAEDSRVAVRNIRRDSNDELKKLEKDHTASEDEVKRAQDDVQKMTDKFVKEIDRIMGTKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC24_CANAL
Sequence: MTTSVDKLNKLIEEVNNQDELQLIEEINLYIKTLYELRQVKIDQLSNIIHQLNQQIITSNKEINQLNKINDYNYELINVNNFNFVSQQSFQFTNFDRSSSSSSESTNNIFQMINKRLNELDNLKVVIVKELTDLETNLNNLKYKQNNLHESMEDINDKLDKLLNDMDKSGIMEQDPSILRINLFRNLGIKLENMPPNANSGGGGDSNSNSSNNNNTEEDCVIITDDNNNVNILNIEPKLSDYFISNYIWDKL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC24.
What is the protein family that this protein belongs to?
Belongs to the SPC24 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: LPXD_PROMT
Sequence: MQFIEIVEKLKKGQSGVVDFKIKNNPVILTAASLENAKDNDISFLDNNSPLNLRNLIETSKASALLLPANDTYIIEIAKKISVDWIILKEPKIAFAETLEFLYPSNVESEGIHKSAVIGQNVKIGLGVSIGANAYIGDNTEIGAGTIIHAGVVLYRNVRIGSKNLIHANSVIHSGSKLGDKCVINANAVIGGEGFGFVPTSNGWKKMPQVGIVILKNKVEVGSGSTIDRPSVGETIIGEDTKIDNLVQIGHGVTTGKGCAMAAQVGIAGGAQIGDGVILAGQVGISNRVKIGDGVIASSKTGIVSNIEAGTVVSGFPAIPNKLWLRCSANFKKLPEIAKAIRQLDRKKSR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL3_METMJ
Sequence: MPKINRPRRGSLAYSPRKRAKSPVPRYGSWPEYTGAPAVQGFAGYKVGMTHVIMVDDHKSSPTEGKDVMVPVTVVEVPPMRVAGVRAYGEDTYGKHALTEAWTTDLDEELSRRINVPKNHDTAAALEAVKAAVGEGKVSELYALAYTRPMELTGVPKKVPDLMEMRIAGGSLEDQIAYAAEILGKEITISGNLEVGEYVDVTAVTTGKGTEGPVKRWGVQVRKRKHSRGGKKRHIGNLGPWHPHHVRWQVPQMGQMGYQQRTEFNKRILKIGADGDEITPAGGFLHYGLVRGPYVLIKGSVPGPNKRLVRIRSAIRQGEHTVRTPAINFVSVQSQQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATPB_TUPAK
Sequence: MVLSIQTNKNVGSITQIIGPVIDAAFAPGQLPNIYNALVIKGTNQAGQEVAVTCEVQQLLGDHCVRAVAMNATDGLMRGMNIVDTGKPLTVPVGKVTLGRIFNVLGEPVDGLEAVDSKESLPIHRKAPAFVDLDTKLAIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVIQEKNMSASKVALVYGQMNEPPGARMRVGLTALTMAEYFRDINKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGGLQERITSTKDGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPWIVGEEHYSCAQNVKETLQRYKELQDIIAILGLDELSEEDRKVVARARKIERFLSQPFFVAEVFTGSPGKYVSLKETIQGFNKILTGELDDLPEQAFYLVGTLDEAVAKAATL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PDXA_ACIF2
Sequence: MITEPRLLLTVGEPAGIGPDICLQLAFHALPSGVLLIGDLHCLRSRALTLGLSLRLEPWLEGNPWPALERGVLHVLDVPLAQPCRPGRLDMANAPAVLATLDKAMHLLRAGAADALVTAPVHKGIINDAGIPFTGHTEYLAAACGSPKVVMLLAGRGLRVALATTHLPLAQVAAAVTQEGLEGTLRILHRALREDFALSEPRILVAGLNPHAGEGGHLGHEEQDVIAPVIAALQGESLRISGPWPADTLFTPRLLEDADAVLAMYHDQGLPVLKYHAFGEAVNITLGLPIVRTSVDHGTALDIAGTGRAEGGSLLRALDNAAEIVRNRRAAGC
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1875_BORPE
Sequence: MRRPAPYHRVAAIMTILSLAGAGHQARLDARGGMLTGPTANLAPGHVQANLAILPQAVAGDFLRFCQRNPKPCPLLAVSEPGDPSLPELGLDIDIRTDVPRYRVWRDGKLVDEPLDVRGLWRDDLVAFLIGCSFSFEEAMLENGLPVRHIEQGCNVPMYRTNIATHPAGPFSGPLVVSMRPLKAADAIRAIQVTSRFPSVHGAPVHLGDPALIGIADLGRPDYGDAVEIRAGEIPVFWACGVTPQSVVAAVRPEFCITHAPGHMLVTDLLNSRLAAF
What are the official names of this protein?
Putative hydro-lyase BP1875.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: MURB_BRUME
Sequence: MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDGGVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGIGGALRMNAGANGVETRERVVEVRALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTSAWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGKIV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BRUC2
Sequence: MAKEATRVRRRERKNISSGVAHVNSTFNNTMITITDAQGNAIAWSSAGAQGFKGSRKSTPFAAQIAAEDCAKKAQEHGMRSLEVEVCGPGSGRESALRALQAAGFVITSIRDVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MIAA_PSEA6
Sequence: MNQHTDNQQLPPAILLMGPTASGKTALAIELCQALPCEIISVDSALIYKGMDIGTAKPTAEELAQAPHRLIDILDPVQSYSVAEFRRDALAAMQDITQRGRIPLLVGGTMMYYKALTDGLSTLPQADPLVRAEIEKQAEKNGWQALHQELQGIDPVSAQRIHPNDPQRLSRALEIYRISGKSMTELSLNKQPSAPYQFSQFAIAPSDRHILHDRIAQRFDIMLNSGFEDEVIELKSRADLHLDLPSMRCVGYRQMWQYLDGENIYQEMREKGLAATRQLAKRQLTWLRSWQNLHWLDTFSKDNLTNVMKLSRIRT
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPB_ECO45
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTKIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETDVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: QPCT_DICDI
Sequence: MKYLKILIIVTIFFFLLINVINCIDRKEIVQKEVKIKFKNLKSTLIKKYSESNMEKIQKHLKHILVERVADTPNHKKVREYIISQFDQLYWDIELDSFKDNTPFGEKTFTNIIVTSKFVNDDDEDDIDTKESNGNISSEPPKTLVLSAHYDSKYFKEFKFFGATDSAVPCSMLIDLAISLQSEIKKSKKKLMIIFFDGEEAFKEWSDTDSLYGSRHLANLLLDKKVITKDNEDLPISSSFYNTVEAFILLDLLGTPNPRFYMFNKKTESLFKKLSDIEDKLSLKRFISPKANKYFQNHFIGSDIQDDHIPFLNYVPTLHIIPYPFPNVWHTEKDDESCLDKNTIEDLSKIFKIFVGSYLI
What is the function of this protein?
Responsible for the biosynthesis of pyroglutamyl peptides.  Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue.  Also catalyzes N-terminal pyroglutamate formation (By similarity).
What are the official names of this protein?
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, Glutaminyl-tRNA cyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the glutaminyl-peptide cyclotransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX3_PELCP
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDIIRESTFQGHHTPSVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.