PharMolix/UniProtQA huggingface dataset:
Protein: PURL_CERSK
Sequence: MTEPEITPELIAAHGLKPDEYQRILEIIGRAPTFTELGIFSAMWNEHCSYKSSKKWLRTLPTTGPQVICGPGENAGVVDIGDGQAVIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPIAAMNALSFGEPSHPKTAHIVKGVVEGIGGYGNAFGVPTVGGEVRFHRAYNGNCLVNAFAAGLADADRIFYSAASGVGMPVVYLGAKTGRDGVGGATMASAEFDDTIEEKRPTVQVGDPFTEKRLLEACLELMASDSVISIQDMGAAGLTCSAVEMGDKGDLGIRLQLDAVPQREANMTAYEMMLSESQERMLMVLKPEKEAVARAIFEKWDLDFAIVGETIPEDRFLILHGNEVKADLPLKALSGTAPEYDRPWIETPAAAPLGAVPEVDPIEGLKALIGSPSYAHKAWVWEQYDSQVMADTVRAPGLGAGVVRVHGTPKALAFTSDVTPRYVKANPFEGGKQAVAEAYRNLTAVGARPLATTDNMNFGNPEKPEIMGQFVGAIEGIGAAVAALDMPIVSGNVSLYNETDGVGILPTPTIGAVGLLTSLDELIAGEPQAGDLALVIGTTAGHLGQSALLAEMFGREEGDAPPVDLEAEKRHGEFLRANRKLVRAAADLSDGGLALAAFEMAEAAGLGLTLTPSGTAALFGEDQARYLVACAPDRAEALQAAAEAAGVPLQEVGRFGGAAVTLAGASAPLADLSRLYRRAFAEAIGG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SHISS
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RS21_PARDP
Sequence: MQVSVRDNNVEQALRALKKKLQREGVFREMKLKQHFEKPSVKKAREKAEAVRRARKLARKKAQREGAL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: 5DNU_SALPB
Sequence: MKQSHFFAHLSRMKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGQLNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMAPDELRDIFAPLIDENAWSEEEQAIVKQADALCAYLKCLEELSAGNNEFGLAKTRLEKTLELRRSQEMDYFMAVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMCPA_LEIME
Sequence: MARRNPLLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAFKQNMQTAYFLNTQNPHAHYDVSGKFADLTPQEFAKLYLNPDYYARHLKNHKEDVHVDDSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQMLVSCDNIDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPCHDEGEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSLCLAWSLNHGVLIVGFNKNAKPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNYPVSATVESPHTPHVPTTTA
What are the official names of this protein?
Cysteine proteinase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: 3MGH_CLOD6
Sequence: MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISDFYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: Y3569_HALH5
Sequence: MNVKEEIDIVIITGMSGAGKTVAVQSLEDLGYFCVDNLPPALIPKFIELIESSSGKMNKLALVIDLRGQTFFDQLFESIDLLDQSSLSKYNIQILFLDAKDAKLVQRYKETRRSHPLAKHGLPLDGIKKERELLEDLKGRAQQIIDTTDLKPIQLREKIIQRFSCEEHHSFTVNMMSFGFKYGIPIDADLVFDVRFLPNPHYVDHLRPKTGLEGEVSSYVLKWTETQQFIEKLEDLLSFMLPQYKREGKSQVVIGIGCTGGKHRSVTLAEHFAKVFANEYMMHVSHRDVEKGKER
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BH3569.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RP25L_HUMAN
Sequence: MEHYRKAGSVELPAPSPMPQLPPDTLEMRVRDGSKIRNLLGLALGRLEGGSARHVVFSGSGRAAGKAVSCAEIVKRRVPGLHQLTKLRFLQTEDSWVPASPDTGLDPLTVRRHVPAVWVLLSRDPLDPNECGYQPPGAPPGLGSMPSSSCGPRSRRRARDTRS
What is the function of this protein?
May be a component of ribonuclease P or MRP.
What are the official names of this protein?
Ribonuclease P protein subunit p25-like protein, RNase P protein subunit-like p25, Rpp25-like protein.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAE_RICFE
Sequence: MLAIGITGSYASGKTFILDYLAEKGYKTFCADRCIKELYQDLSVQTQILKLLPELESFNIGKISNLIYNNDLAREKLQNFIYPLLIDKLILFKKENANSKFGFAEIPLLYEAKFDKYFDFVVTIYCSEEIRMQRAITRTSFDIEIYNKIKEIQLSQESKIAKADFAINSGVDMLDLEKQIEKLILVIARKL
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIAA_ERWT9
Sequence: MISLDTLSLFLSINENDLVEELVMTLLASPQLAVFFEKFPVLKNVLTRDLPRHKADILQQLKSTAVPPLLEAEFQRFQQYQALSLRDFNAGLPDLLAWLAHQASPFNEKAQALIANNDTQQCNSAQQTLFLQRWRLSLTLQTLTLNQQLLDKEREKLLAELQQRLAMSGQLAPVLADDDEAAAGRLWDLTRGELQRDDYQLIVQYGDFLASQPELLKLAQRLGRSREAKPVPSDDAPAEIFHQPVREPASVPEEVNGLHQSDDILRLLPPELATLGISELEIEFYRRLVEKRLLTYRLQGESWHDHITQRPVAHQHHDPQQRGPFIVCVDTSGSMGGFNERCAKAFCLALLKVALAEKRRCYIMLFAHQVISYELTAGDGISQAIRFLSQRFRGGTDLAACLEAVLVKLSDVQWHDADAVVLSDFIAQRLPDALITRVRTHQEQQRQRFHAVAMSDHGKPGIMRIFNHIWRFDTGLKSRLLRRWKR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: MYL3_PONAB
Sequence: MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium (By similarity).
What are the official names of this protein?
Myosin light chain 3, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB.
Protein: TIFA_MOUSE
Sequence: MSTFEDADTEETVTCLQMTIYHPGQQSGIFKSIRFCSKEKFPSIEVVKFGRNSNMCQYTFQDKQVSRIQFVLQPFKQFNSSVLSFEIKNMSKKTSLMVDNQELGYLNKMDLPYKCMLRFGEYQFLLQKEDGESVESFETQFIMSSRPLLQENNWPTQNPIPEDGMYSSYFTHRSSPSEMDENEL
What is the function of this protein?
Adapter molecule that plays a key role in the activation of pro-inflammatory NF-kappa-B signaling following detection of bacterial pathogen-associated molecular pattern metabolites (PAMPs) (PubMed:11798190).  Promotes activation of an innate immune response by inducing the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism (By similarity).  TIFA-dependent innate immune response is triggered by ADP-D-glycero-beta-D-manno-heptose (ADP-Heptose), a potent PAMP present in all Gram-negative and some Gram-positive bacteria: ADP-Heptose is recognized by ALPK1, which phosphorylates TIFA at Thr-9, leading to TIFA homooligomerization and subsequent activation of pro-inflammatory NF-kappa-B signaling (By similarity).
What are the official names of this protein?
TRAF-interacting protein with FHA domain-containing protein A, TRAF2-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TIFA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with lysosomal marker LAMP2 following homooligomerization and subsequent activation.
Protein: ANM8B_DANRE
Sequence: MGLRHSSRCLLLRRKMAEAESTEQQQQKHKQPQHQQQQSISSIPSSQSLQPSPLPKPVTSVHHVPPHPPHTPHVSALSACPGRGKMAKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITILKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGFMFPDRATLYVVAIEDRQYKDFKIHWWENVYGFDMTCIRNVAMMEPLVDIVDPKQVVTNSCLVKEVDIYTVKTEDLSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSITVRPNENNERDLDFTFELDFKGQLCDAAISHDYKMR
What is the function of this protein?
S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).
What are the official names of this protein?
Protein arginine N-methyltransferase 8-B, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4, zfL3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT8 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RS18_MYCAP
Sequence: MANFKKVKKGRNLRRKCELCETNIEYVDYKNVEFITKFISGIGQIKPHVSTGTCARHQRKVANAIKRARFMALIPYTKDKIRVLAPAASANTAQAPAEKAKKEAVAA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TDT_HUMAN
Sequence: MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRQFERDLRRYATHERKMILDNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
What is the function of this protein?
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.  One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
What are the official names of this protein?
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXD_THIDA
Sequence: MAVTLAALVERFGGELVGDSARSVRQVAPLDRACADDIGFVSQSKYLAELATTGAGAVILPPDARDATDLPRILTPNPYLYFARVSALLNPPPRPAAGVHPAATVAADAEVAADASIAAGAVIGSGARIGARSVIGANSVVGDGARVGEDCLLHANVSLYHGCQVGDRVILHAGCVIGADGFGFAPNEGRWEKIPQIGRVLIGDDVEVGACTTIDRGALEDTVIEEGVKLDNLIQVAHNVVIGAHSAIAACTGIAGSAKIGRHCTIGGAAMIFGHIEIADGTRISTNTLITKSLPKRGTYTSALPFSEHEVWQKNAVHMRNLDKLVTRVKQLEKRLNELENKT
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y980_MYCBO
Sequence: MNRVSASADDRAAGARPARDLVRVAFGPGVVALGIIAAVTLLQLLIANSDMTGAWGAIASMWLGVHLVPISIGGRALGVMPLLPVLLMVWATARSTARATSPQSSGLVVRWVVASALGGPLLMAAIALAVIHDASSVVTELQTPSALRAFTSVLVVHSVGAATGVWSRVGRRALAATALPDWLHDSMRAAAAGVLALLGLSGVVTAGSLVVHWATMQELYGITDSIFGQFSLTVLSVLYAPNVIVGTSAIAVGSSAHIGFATFSSFAVLGGDIPALPILAAAPTPPLGPAWVALLIVGASSGVAVGQQCARRALPFVAAMAKLLVAAVAGALVMAVLGYGGGGRLGNFGDVGVDEGALVLGVLFWFTFVGWVTVVIAGGISRRPKRLRPAPPVELDADESSPPVDMFDGAASEQPPASVAEDVPPSHDDIANGLKAPTADDEALPLSDEPPPRAD
What are the official names of this protein?
Uncharacterized protein Mb0980.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVC_SALTY
Sequence: MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NHSL2_MOUSE
Sequence: MPFYRRTVVPQRLCPRNPPQPLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEDDEELLAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFRSSDGAPEPTPSPRPQSAKRLEFVLMPAKRQLSEDETTTQGVRAPEACLSLSTANKQSAWNDPFPLPILKERLWLQPCSTQSDLVPINISGQQFDRHASFRHSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSSSPTGSLARSATSDIRPGHSAPQVVQGRVAVGQEARFPSLTSPGLRHSSSEPGDAHQARSASDHPGMESMAVVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSASSQGNQVSENGKNPSSGNSWVPLNTLPPLVPKEAATLFVTRDNPAGCTGLPSYSEHPTLRRQIPERPPKIGLLARGTSRLETGPGGTNRFRERSLSVPTDSGVTSVDYDEEQKTSETRILPYASTSSEGSNSTDNIAALSTEQEARHRRQRSKSISLKKAKKKPSPPMRSVSLVKDEPALPPEGELVLPKDQRPRSLCLSLEHQGHHPPHPDAQGHPAVPMLKDPGSTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVASPGRPTGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSASVRVRPVVPERKSSLPPTSPMEKICKSRLSFDLPLTSSTTLDLSGMSISIRSKTKVSRHHSDTNFGVKLAQKTSPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPDYIEEPGAEEVFTMPERKVKPPIAEKPPLARRPPSLVHRPPSLPGEYPLTSPTMAMASRSSIPHMKQLPQDSYTVLRKPKSPSFPGESTASSSLVLSPLASSSGAFFSGTQQPPQASVEDGGPKVRALPERIGLQSQEEAEKKMTKIPPPVPKKPSVLYLPLTSPVAQMDACMAEPRLPFSPIITLEEDGKCPSTGDDQKSPGKGVTSPLHTDTEKEAISPGRSVEPSAEEKSLISDKTAEWIAEEEDDVFVASRTTEDLFTVIHRSKRKLLGWKETGEGFTGSKPSSHSPVKNTADSPTGEAAAAPGPSSSACLDAGRNDDFKALLQKKGSKATPRTRPSAAELLKTTNPLARRIIAQFSKDYEPTDNPST
What are the official names of this protein?
NHS-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the NHS family.
Protein: Y734_STAAR
Sequence: MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVITQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEKSLLRVIHRIKELD
What are the official names of this protein?
UPF0178 protein SAR0734.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: HYBE_ECO57
Sequence: MTEEIAGFQTSPKAQVQAAFEEIARRSMHALSFLHPSMPVYVSDFTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGVSQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGENA
What are the official names of this protein?
Hydrogenase-2 operon protein HybE.
What is the protein family that this protein belongs to?
Belongs to the HupJ family.
Protein: NUSB_RICRS
Sequence: MSSNKINKKSIARIAAVQAIYQNILQNNDDMDDIMQNVLSFYQNNNSITDLPENLKISLSISHFKMLVKLVFENIHKLDEIIDNHLTNDKDPAHMPILLRALLRVSICELLFCPTTPAKVVINEYTDIANDMLNEHEIGFVNSVLDKIAKEHTRLI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CCD47_HUMAN
Sequence: MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:32814900, PubMed:32820719, PubMed:36261522).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein (By similarity).  Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (By similarity).  Involved in the regulation of calcium ion homeostasis in the ER (PubMed:30401460).  Required for proper protein degradation via the ERAD (ER-associated degradation) pathway (PubMed:25009997).  Has an essential role in the maintenance of ER organization during embryogenesis (By similarity).
What are the official names of this protein?
PAT complex subunit CCDC47, Calumin, Coiled-coil domain-containing protein 47.
What is the protein family that this protein belongs to?
Belongs to the CCDC47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane.
Protein: OR6V1_HUMAN
Sequence: MANLSQPSEFVLLGFSSFGELQALLYGPFLMLYLLAFMGNTIIIVMVIADTHLHTPMYFFLGNFSLLEILVTMTAVPRMLSDLLVPHKVITFTGCMVQFYFHFSLGSTSFLILTDMALDRFVAICHPLRYGTLMSRAMCVQLAGAAWAAPFLAMVPTVLSRAHLDYCHGDVINHFFCDNEPLLQLSCSDTRLLEFWDFLMALTFVLSSFLVTLISYGYIVTTVLRIPSASSCQKAFSTCGSHLTLVFIGYSSTIFLYVRPGKAHSVQVRKVVALVTSVLTPFLNPFILTFCNQTVKTVLQGQMQRLKGLCKAQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6V1, Olfactory receptor OR7-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STS2_POSPM
Sequence: MSSSVSSTSAPTKIVIPDLVSHCTIPVRCNRHWKQASVESKRWLFRGGNLSDRKRDAFHGLKAGYLTSMCYPLAGYPQLRVSCDFMNYLFHLDNISDEMNDRGTHGTAVSVLDALYQPHMHPTSRVGKMTKDYWVRLIQTASPGAQQRFIETFDMFFQAVTQQAMDRANGVIPDLESYIAIRRDTSGCKPCWALIEYANNLDLPWEIMDHPIIRGLGEAANDLVTWSNDIFSYNVEQSKGDTHNMIVVVQNQQGLDLQSAVNFVGDLCKQSIDRFHYLRENLPSWGPELDREVEIYVDGLADWITGSLKWSFESERYFGKAGLEVKKTRVVALLPRRA
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to various sesquiterpenes, including alpha-copaene, beta-copaene, beta-elemene, alpha-muurolene, gamma-muurolene and delta-cadinene.
What are the official names of this protein?
Sesquiterpene synthase 2, Terpene cyclase 2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RS6E_METM7
Sequence: MAFKVVVSDTKTGKSYQFETESTALIGKKIGDEISGSVVELEGYKLKITGGSDKCGFAMRHDIHGAMKMRVLLKEGPGYNVKEKGLRRRKSLRGNTISKDVTLINTKVVEYGSAPLGGEPESTE
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: M2_I83A4
Sequence: MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILDRLFFRCVYRRLKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: UVRC_BORBZ
Sequence: MKENLTNLFEKVIKLPTTSGCYKMLNENKKILYIGKAKNLRSRVKSYFLEKNSHKIKILMKNVKSIEVITTNSEYEALLLECNLIKTHKPDYNVKLKDGKGYPMVRITHEKYPRIFKTRKIINDKSEYFGPFTNVKKLDQVLDFINKTFKIRKCKKKSNAPCLYYHMGQCLGVCYKENLEKEYQKELDKAKSILNGNISEISSQIDIKLKHAIQKEDFETAIKLKEIRNSLIEINQIQIVTKTNNLNIDYVHVHPGENVNTIIVLKYRNGKLVERDANFDESICKENELILQFLIQYYTSINMIVPDKIHIFLKDIDTKNVEKLINEIKNTKTEIIYKETEEILKIMEMAISNAELSLREYENKSTKALESLKIVLEMDKLPKIIEGFDIAHLKGQETVASMVTFKMGMPFKENYRLYKLNSLLKGEIDDFKAIKEVISRRYSEIINNNLELPNLILIDGGKGQLNAALSILKGLKIENKVKVCSLAKKQETIFLTTNKKGINLPQGHPALRILQNVRDEAHRKANGFNKKRREKITLLYTKIHGIGEKTAQKILKSIGTYKDILPLSENEISEKIKVNVQLAKRIKEFAIKENSIKNNNQDK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.