PharMolix/UniProtQA huggingface dataset:
Protein: IKBL1_MACMU
Sequence: MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSCRPPRAEGSSQSWRQQEEEQRLFRERARVKEEELRESRARRAQEALGDREPKPARAGPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
What is the function of this protein?
Involved in the regulation of innate immune response.  Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways.  Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity).
What are the official names of this protein?
NF-kappa-B inhibitor-like protein 1, Inhibitor of kappa B-like protein, I-kappa-B-like protein, IkappaBL, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus (By similarity).
Protein: NRDI_ECOK1
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCSVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: TRMD_STRLI
Sequence: MRLDVVTIFPEYLEPLNVSLVGKARARGQLGVHVHDLRDWTYDRHNTVDDTPYGGGPGMVMKTEPWGDALDSVLADGYETGCGEPALVVPTPSGRPFTQELAVHLSERPWLIFTPARYEGIDRRVVDEYATRMPVYEVSIGDYVLAGGEAAVLVVTEAVARLLPGVLGNAESHRDDSFAPGAMANLLEGPVHTKPPQWRGRGIPDVLLSGHHGKIARWRRDEALRRTTANRPDLIERCDPAAFDKKDREMLSILGWQPDPDGEPYGRFWRRTPGMEE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_SYNWW
Sequence: MAEEKEVVLTKEGLEKLENELEHLKSVKREEVAERIKQAIAFGDITENSEYEDAKNEQAFIEGRIISLEKTLKKARLMEDEDIRTDVVSLGSRITLKEMKSGREVTVTLVSSVESKLKDGKISDESPVGKAIMGKKVKSTVSVEAPAGTIKYKIIKVEK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: PEX6_NEUCR
Sequence: MTAPNSTPASSRKRVRRRRQDKPALSAKLVLDAHVKGDVGVIATDLFADLFPHLWANGDSQDTVHVAIAPWAPSQTPEANNWSIVPVIRSSTVAPSTVQFSPSSLALQSFATHLQQAAPSKLSGHNKGGIEILILDVSPIELDTVFVNLDGELAKRLEDGEGTFFREHPVNGKGKARADATPEEHLTAALRTALGTLKIVHSGDFFPLPLPPHPVTHQPPNPGRITLCEPVAQGILAPTTKIIVSRVRTSKTKRSSASGQQQGRKLNGVAEDDEDAYFSAAEEDRDSKTNAQTAETDADDTEFEPQAGEDEDNLSDDSLDEIISLQVPTLPTTVTGQSTIGTGTPTMLRGRKTNGPGSVISSYTATTARPDRPRGRLFKAHGLMKPIPPDLLHPKPTPEDDEEACIYVDMRDLTRVGCFSGDWIRVEAASEPPSNGLGAFGLGSFVEQEADEINWRPARVFGLPEGYSSRSATRSHHSRHDSRNSSFFEAQSQKSNPPAYTSPILLANLDNPPYLRLSPIKRPSSSIIKGVAAQSKTSSTLKPPFAREVILQHVRTPTAVERDVQSAVMAGLKHYFERRLRVLRTGDLIAVPIDTQLGKALQESTIPGEDSAIDEVLGLIAATRPGQSLHYDDVAWFRVGHVQAMKQDTTEAVDGEEAEDLWGGIACVDISLTHLEQSGSVTGRIPGTISNSWQYYLGIRKLPKHQQNPGLPAQLQTLEPEKQYVSSLRRKLRELMAAATSKPALHLNLPPLAILLVSTQRHIGKAATAMQACSDIGLHTFAIDAYDIVNDGGGGGGSDVKTAGFLTSRAERAMSCGPESCVLLVRHIEALTADRMVSSIKEILADARVLIATTTEVEKVPDGIRALFTHELEMSAPDEQEREGILSSILADRGIGLDHGVDLSGIALKTAALVAGDLVDVVDRALVAQRSRLEKLTAKATGSITFRDVQLAGGPAASGLTKQDFELAVDAARKNFADSIGAPKIPNVTWDDVGGLGNVKDAITETIQLPLERPELFAKGMKKRSGILFYGPPGTGKTLLAKAIATEYSLNFFSVKGPELLNMYIGESEANVRRVFQRARDARPCVVFFDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSGGEGGGGGVFVIGATNRPDLLDPALLRPGRFDKMLYLGVSDTHDKQVTIMEALTRKFTLHPTVSLRSVAERLPFTYTGADFYALCSDAMLKAVTRQATLVDTKIRELNAAAGPEGKQISTAYFFDHYATKEDISVMVTEQDFLDAHRELVPSVSAGELEHYEQVRAMFEGAKDKDKKKEGAGGDGNGVDGLESGNRNGMLAITMGDDGAGAESTKKDGKGKGKAADNEVNGAGEGKGKEGVSPFQESGGDEDEGLYD
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: RRAA1_ARATH
Sequence: MAFVTTAEVCDANQEMIRSGQLRALQPVFQIYGRRQIFSGPVVTVKVFEDNGLIRHFLEEKGNGRVLVVDGGGSLRCAILGGNPVVQAQNNGWAGIIVNGCIRDVDEINGCDIGVRALASHPIKASKKGLGEQRVSLNIAGTRICDGEWLYADTDGILVSQIELSV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 1, HMG aldolase 1, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog 1, RraA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ISPE_BIFLS
Sequence: MSPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIGVYDTVTATAKQPGAGFSLELEGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALTITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRTIAATLGADMPFCLTGGLAYGTGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHLQAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDRIIRAKSPAHPNIGVRQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: AROC_PHEZH
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGVPLTEADIQPWLDRRRPGQGKFVTQRQEPDAVRILSGVFQDERTTAKFGGQVTTGTPISLIIENTDQRSRDYSEIATSFRPGHADYPYFAKYGVRDYRGGGRSSARETAARVAAGAIARKLLPGVTIRGAVVQIGPHAVDPGRIDFSVTGDNPFWAPDPEIVPVWERHLEQVRKAGSSTGAVVAVEATGVPAGWGAPLYGKLDAELAAALMSINAAKGVEIGAGFAAAALSGEENADEMRMGNEGPLFLSNKAGGVLGGISTGQPVTARVAFKPTSSILTPRRSLDEAGREIELRTKGRHDPCVGIRAVPVVEAMVACVLADALLRHRAQTGGGAHVLGENPKS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: IHFA_BUCAP
Sequence: MVVTKAAISENLFEKLKLTKRDSKEFVEFFFEEVRKSLEKGEDVKLSGFGNFQLKNKKERPGRNPRTGENILITQRRVVIFKAGQKLKNRVEHYLMKVKY
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: THII_METS3
Sequence: MNYDVVIARYGEIGLKSSKVRARFERKLVKNIKAAIDCEVDRNQGRIYIFPKNYGECLENLNKVFGVVSYSPAVSTYGNYEDIEKTLGEYVDNLVDDGFIGKDTRFAIKCRRVGNHDFTSQEMAAFCGSVVVKKVGCPVDLTNPELKIYVEVRDDEAFIYHEKIDGPGGLPLGTQGKVVVLVSSGIDSPVAAYLMMKRGCEVIALHCDNAPFTGPKVHENFDKIIDQLQSYAKGVPITKKVVKYGEYLQQAKDCAPEKMTCVLCKSGMYKIAEKLAHKYGASAIVDGSSVGQVASQTLSNILATRHGVDMPILSPLIGLDKLEITRIAEDIGTFEISKLDDGGCHAVPKYPETKADVDRVEEACRAMNQKEAIEKAFDSID
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_BURVG
Sequence: MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVSVPGALEIPLALQKLAESGQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFNLPIANAVLTTENDEQAVARMTEKGRDAARVAVEMANLTMALDQLGDDEEEDEDDEEERA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KCNJ6_MOUSE
Sequence: MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQSDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGIVEATGMTCQARSSYITSEILWGYRFTPVLTMEDGFYEVDYNSFHETYETSTPSLSAKELAELANRAEVPLSWSVSSKLNQHAELETEEEEKNPEELTERNGDVANLENESKV
What is the function of this protein?
This potassium channel is controlled by G proteins.  It plays a role in granule cell differentiation, possibly via membrane hyperpolarization.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 2, GIRK-2, Inward rectifier K(+) channel Kir3.2, Potassium channel, inwardly rectifying subfamily J member 6.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS6_ONYPE
Sequence: MKKYEIMYILRPNLDSKDVKKINDTLQNVFLQAPNQILEQNEIGLKDLAYLIDNHKKGYYNWLMVKADNDAVLEFNRIVKITEEIIRFIFIKDKE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: THUM3_MOUSE
Sequence: MSCDTQEATRECLGMNLDGNKEPVSLVESGVRSESEHLQVTIGATVPTGFEQTAAGEVREKLKSACRISKDRGKIYFDIAVESLAQVHCLRSVDNLFVVVQEFKDYQFKDTKEEVLRDFEELAGKLPWSDPLKVWQINTTFKKKKAKRRKANQSAGKEKADCGQGDKADEKDGKKKHASSTSDSHILDYYENPAIKEEISTLVGDVLSSCKDETGQSLREETEPQVQKFRVTCNRAGEKHCFTSNEAARDFGGAIQEYFKWKADMTNFDVEVLLNIHDNEVIVAIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAGDNNPLAVNRAANNISSLLTKSQIKDGKTTWGLPIDAVQWDICNLPLRTASVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPGTGRAVLLTQDKKCFTKALSGMGHVWRKVHVVWVNIGGLHAAVYLLKRTAQAFVHPSDQDEGRDPPW
What is the function of this protein?
Methyltransferase which catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates containing the characteristic 3'-CCA terminus of mature tRNAs (By similarity).  Also catalyzes the formation of N(2)-methylguanosine at position 7 of tRNA(Trp) (By similarity).  Requires the methyltransferase adapter protein TRM112 for tRNA methyltransferase activity (By similarity).
What are the official names of this protein?
tRNA (guanine(6)-N2)-methyltransferase THUMP3, GtROSA26asSor, THUMP domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_BACSU
Sequence: MAELRSNMITQGIDRAPHRSLLRAAGVKEEDFGKPFIAVCNSYIDIVPGHVHLQEFGKIVKEAIREAGGVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVSAHWFDGMVCIPNCDKITPGMLMAAMRINIPTIFVSGGPMAAGRTSDGRKISLSSVFEGVGAYQAGKINENELQELEQFGCPTCGSCSGMFTANSMNCLSEALGLALPGNGTILATSPERKEFVRKSAAQLMETIRKDIKPRDIVTVKAIDNAFALDMALGGSTNTVLHTLALANEAGVEYSLERINEVAERVPHLAKLAPASDVFIEDLHEAGGVSAALNELSKKEGALHLDALTVTGKTLGETIAGHEVKDYDVIHPLDQPFTEKGGLAVLFGNLAPDGAIIKTGGVQNGITRHEGPAVVFDSQDEALDGIINRKVKEGDVVIIRYEGPKGGPGMPEMLAPTSQIVGMGLGPKVALITDGRFSGASRGLSIGHVSPEAAEGGPLAFVENGDHIIVDIEKRILDVQVPEEEWEKRKANWKGFEPKVKTGYLARYSKLVTSANTGGIMKI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD, Vegetative protein 110, VEG110.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SNR27_HUMAN
Sequence: MGRSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPSRLKERRDEEKKETKETKSKERQITEEDLEGKTEEEIEMMKLMGFASFDSTKGKKVDGSVNAYAINVSQKRKYRQYMNRKGGFNRPLDFIA
What is the function of this protein?
May play a role in mRNA splicing.
What are the official names of this protein?
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, U4/U6.U5 snRNP 27 kDa protein, U4/U6.U5-27K, Nucleic acid-binding protein RY-1, U4/U6.U5 tri-snRNP-associated 27 kDa protein, 27K, U4/U6.U5 tri-snRNP-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the SNUT3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URK_ALIFM
Sequence: MSENSNHHCIIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDSYYKDQSHLTMEERVKTNYDHPNALDHELLCEHLEQLMRGEAVNIPTYSYTEHTRTSEVDVMTPKKVIILEGILLLTDPRLRNLMHASVFMDTPLDICLLRRARRDVEERGRTMESVFEQYQKTVRPMFMQFIDPSKQHADIIVPRGGKNRIAIDVLKAHISRLLKA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRL4_DANRE
Sequence: MKLLLFAAWFSSLLDPCRFLDICQSCHPNADCDDICKCRTGYTGNGISDCRDDNECETVPEICGLHANCTNYVGGYYCNCLSGFISNGTEQFQTNDGTSCNDINECEEDRKCGPNSKCHNNIGSFICSCLRGYTSPAGPWFMPNHGTDCIENSKIHCHQDHKCTKETVNSTLERMTNLSISERLKEIRYQTSAALSPVLLISYIEAMVSSKLNSGDVSKDSKEHVNETITNLVFSVNNLVEKDEKVEWKKINEDLRMYYVTKLLHTAEKETLALSAGYTHATQMQVHAGDVEMKLYTFEPRQAQKHPLSANIQGNSISLSTKKARHANNNGSTSVVFLIYHSIGDLLKPADDPGVADYSRYAAAGEITVNSPVIAAAISNQKTLPLNDVTFTLKHTQEIDPARDETKCAFWEYSPSMMGHWSLDGCIRTRVNTTHTSCSCNHLTHFAILMSSARANLLAHYNVLTRITQLGMVISLICLSMCIFTFWFFRDIQNTRTTIHKNLCCSLFMAQFIFLIGINKSAHKWFCSLIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHRNFYAFGYGSPAVVVAISATLGYKYYGTSSVCWLSTENNFIWSFIGPAILIILVNLLAFAVIIYKVYRHTAVKKPEISHYENIRSCARGAIALLFVLGVTWAFGVMYILYETTLTAYLFTFANVFQGMFIFIFLCVLSRRIQEEYYRLFKNMPCCFECLR
What is the function of this protein?
Orphan receptor that plays a role in vessel formation.
What are the official names of this protein?
Adhesion G protein-coupled receptor L4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_STRP8
Sequence: MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ATP6_ACIET
Sequence: MAADAHAPTASEYIVHHLQHLQNIKQKSIIDFSVVNLDSVAVSVILGVLGLFVMWLAARTATSGVPGRFQAAVEMLVEMVDNQAKANIHNAQSRKFIAPLALTVFVWIFLMNAMDLLPVDLLPVLWQGATGDSHAYLRVVPTADLSTTLGLSSAVLILCFVYSIKIKGMGGWAHELVTAPFGTSKNPVFALILGVVNLLMQIIEYVAKTVSHGMRLFGNMYAGELVFMLIALMGGAAAMSLSGVLLPVGHIIAGSIWAIFHILIITLQAFIFMMLTLIYLGQAHEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUON_SHISS
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPMGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLYSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSASGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL30_PYRAR
Sequence: MMAEAKLIYPRYAVVRLRGIPTTPRDIARTLDLLRLRRKFTMVVVPGSPSIMGMIQEVNDWVTWGEIEADTLAEVLKKRGRIVGDKPLTLEYLKKWGWQSFEEVALAYVAGEIERLSCGRYYAREGQRPPCIPYLKPFFRLHPPRGGLNSVKLHFAAGGDLGYRGPLINDLIRRML
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y2102_VEREI
Sequence: MPFDPAASPLSPSQARVLATLMEKARTVPDSYPMSLNGLLTGCNQKTSRDPVMALSEAQVQEALAALERLALVFENSGYRSPRWEHNFQRGAGVPEQSAVLLGLLMLRGPQTAAELRTNAERWYRFADISSVEAFLDELQQRSADKGGPLAVPLPRSPGTREQRWAHLLCGPVDAGRSNAGVEPVPAGVETLQERIGTLESELASLRATVQWLCQELGITPAPASMPQPGLPAGNGSPGS
What are the official names of this protein?
UPF0502 protein Veis_2102.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: SYM_ACTSZ
Sequence: MSKANRQILVTCALPYANGPIHLGHMLEHIQADIWVRFQRMRGHEIYFVCADDAHGTPIMLKADQMGIAPEQLIADVQKSHYADFCGFNISFDNYHSTHSEENREFSEMIYNRLKENGFIKTRAISQLFDPEKSMFLPDRFVKGTCPKCKAEDQYGDNCEVCSATYSPTELIAPRSVVSGATPIIKESEHFFFDLPSFEAMLKQWNRSGALQSEVANKMQEWFDAGLQQWDISRDAPYFGFKIPGTENKYFYVWLDAPIGYMASFKNLCNRQNIDFDRFWNKDSQAELYHFIGKDIMYFHSLFWPAMLEGADLRKPSNIFVHGYVTVNGEKMSKSRGTFIQAATYLKHLDPECLRYYYAAKLSNRIDDLDLNLEDFVQRVNTDLVNKLVNLASRNAGFIQKRFAGKLADKLDDEALFNEFIAQSAQIAAYYENREFGKAVREIMALTDKANKYVDEKAPWVIAKEQGRETELQRVCSMGIQLFRVLMGYLKPVLPKLAERSEAFLQAELTWDNLTQPLLDHEIAPFKALFSRVDSKQIEAMIEASKAENAAVNSSPKAEKTAKKTTALESEFEPLEAEISIDDFAKMDLRVAKVISCEAVPESKKLLKFQLDLGFETRQVLSGIKAAYGNPEELMGRFVIMVANLAPRKMKFGMSEGMILSAGSGGEDLFLLDVDAGVKAGSRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ECOL6
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALEMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESR1_SALSA
Sequence: SRMLTDPPRIGSMQSLGSSPTGPLVFVSSSPQLSPFLHPPGHHGLPSQSYYLETSSTPLYRSSVVTNQLSASEEKLCITSNRQQSYAAAGSGVRVFEMANETRYCAVCSDFASGYHYGFWSCEGCKAFFKRSIQGHNDYMCPATNQCTMDRNRRKSCQACRLRKCYEVGMVKGGLRKDRGGRVLRKDKRYCGPAGDREKPYGDLEHRTAPPQDGGRNSSSSSLSGGGGWCGPRITMPPEQVLFLLQGAEPPALCSRQKVARPYTEVTMMTLLTSMADKELVHMIAWAKKVPGFQELSLHDQVQLLESSWLEVLMIGLIWRSIHCPGKLIFAQDLILDRSEGDCVEGMAEIFDMLLATVSRFRMLKLKPEEFVCLKAIILLNSGAFSFCSNSVESLHNSSAVESMLDNITDALIHHISHSGASVQQQPRRQVQLLLLLSHIRHMSNKGMEHLYSIKCKNKVPLYDLLLEMLDGHRLQSPGKVAQAGEQTEGPSTTTTTSTGSSIGPMRGSQDTHIRSPGSGVLQYGSPSSDQMPIP
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPI_PHAAO
Sequence: MNVIPCSIKTLKGLYDISGVEVGQHLYWQIGGLQIHAQVLITSWVVIAILLGSVIIAVRNPQTIPTNGQNFFEYVLEFIQDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIKLPHGELAAPTNDINTTVALALPTSVAYFYAGLRKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.