PharMolix/UniProtQA huggingface dataset:
Protein: PRIM_OSHVF
Sequence: MSNSEKQTLAIEWFKNMSEIKKSRENGLVSKVIAKDVHVLSGAKKYGILWKGKEGEMIDHIAKGQNEHLYEMIDFNSPARLFFDMDFKSKDEFGFGCDIPPNQVVVMFMEELQLFVNKLIGHDSGKFNAKEVLITQCKRLDRPDKHSFHLVYPKIVFRNITQMRAFVLSFGHYLFEEKHMMSLAFQKKGKNRSLGRAVFDMSPYTRDRLFRLMGQSKMGEPYENTLRPVKIQEVYETSNNFFDNLIDDNGISSHAQIITLRYSELENISDYMVQPCSFLDMDATPPSTTLGDLIHNSVLKNYGNVPLKTYVAAKQDRRGVTITLLGNNNKTPGNLKSAKDNILPVDWHTLIKEEFRGKEINIENDEQFLEFFTARELKEADYVYYYLNFISDICHFIPDKTMLTWMNGCDDYVSTRSERKLFYAKESSSKKPITGRFALSLLENVYGVDNVNDLRNPVPKPIGDFKNVKRTVMTTEEWEPIEARDLRSRILTEQNKDLKTNNYINGAITMDFEKEEEYAKIGVPEDEEGNRIEMAQRFNSKKRAYFISGQMGASKSSGTLESIVELVMKGMMKNVLIITPRIVLAKQTILKLFTVYKELLGDSKVKRDFKKTNDIDITAMFHKAYQDKEIRQVKEWCRGRINPEMEHCNICVSLINSIHRLNRAVYDTIIFDEPITCIDNFYIELHTKNSNENAAEVVANTISRRNAIVNRLTGFTMLSNQLFFIDAAFTPDSINLCKSLYYGEYSFIVSPREWNKHMRSEGVGDTTVKNTCKRINKENLEIRKRIRIVKTRSEDKSQMIQKEEVTYKIFREPQMICVYDKSLEKPIFQKIIDYKSKNKLLNTLLETICEGQKVVVYCSTQKESERLYHAVKGWTERKMSWIPRLILITGSTVKKEPGEVVNKIKDGDVIFTTSVLGVGTSISEEGLFDCAFMICKLSVGSPLLSDMIQLSARVRATKNRVLHMNISCGQFGVDCSKLTRELHSFQPANYMYGGFMDCLDITHRNRRLFHHVCISNYTIARETMLSEITDALGHVKDATLSRISPEYIYVKDVDHRFLATRDITEQRQLAQKLDVLDCRMEHTEEFVDFVGLYKNKKEGRRVVAKINVPKKNELLHEFWQKSKIGREGYTPVTHKAYSLKRSHSTMVEHDMDDDESTNKKQELEEEDEECIDIDEYNNERF
What is the function of this protein?
Synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during viral DNA synthesis.
What are the official names of this protein?
Putative primase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: RL16_RHOP5
Sequence: MMQPKKTKFRKAHKGRIHGVASSGATLSFGQFGLKAMAPERITARQIEAARRALTRHMKRAGRVWIRIFPDVPVSKKPAEVRMGSGKGSPELWVARVKPGRVIFEIDGVNLQIAREALTLAAAKLPIKTRFVARIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PVK2_DEREJ
Sequence: GGSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.1, PVK-2.1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_PROMS
Sequence: MLKEPPKNSREKTKNLLLTLQDKICSGLENVDGKGKFTEESWLRDEGGGGRSRVLKNGSIFEQAGVNFSEVQGKELPQSIISQRPEAKGHEWFATGTSMVLHPKNPYIPTVHLNYRYFEAGPVWWFGGGADLTPFYPYLSDVRNFHNEHKKACEKVDQDLHKVFKPWCDEYFFLKHRNESRGIGGIFYDYQDGSGNIYRGNNKNGEASKASQNVGRSNLNWDNLFSLAENCGQAFLPSYLPIIEKRASQKYSPKEREFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLARWEYGYKAKNGSREEFLTSIFTKPQDWFNDKELEKFCMENNIFD
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_NINRI
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RIHC_SALTI
Sequence: MTASLHIILDTDPGIDDAAAIAAALFAPQLDLQLITTVAGNVSVEKTTRNALQLLHFWNSDIPLAQGAATPLLRPLRDAAYVHGESGMEGYDFVDHQRQPLAKPAFIAIRDVLMNAPEPMTLVAIGPLTNIALLLMHYPECACNIRRLVLMGGSAGRGNFTPNAEFNIAVDPEAAALVFRSGLEIVMCGLDVTNQAMLSPDFLNKLPALNRTGKMLHSLFNHYRSGSMRTGVRMHDLCAIAWLVRPELFTLQSCFVAVETQGEYTAGTTVVDIEGRLGQPANAQVALALDVDGFRQWVAEVFAYVP
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: MATRX_SENDH
Sequence: MADIYRFPKFSYEDNGTVEPLPLRTGSDKKAIPYIRIIKVGDPPKHGVRYLDLLLLGFFETPKQTTNLGSVSDLTEPTSYSICGSGSLPIGVAKYYGTDQELLKACTDLRITVRRTVRAGEMIVYMVDSIGAPLLPWSGRLRQGMIFNANKVALAPQCLPVDKDIRFRVVFVNGTSLGAITIAKIPKTLADLALPNSISVNLLVTLKTGISTEQKGVLPVLDDQGEKKLNFMVHLGLIRRKVGKIYSVEYCKSKIERMRLIFSLGLIGGISFHVQVTGTLSKTFMSQLAWKRAVCFPLMDVNPHMNLVIWAASVEITGVDAVFQPAIPRDFRYYPNVVAKNIGRIRKL
What is the function of this protein?
Acts as a negative regulator for transcription and replication by sticking to the nucleocapsid.  This effect might be regulated by the cytoplasmic interaction with tubulin that dissociates the M protein from the nucleocapsid (By similarity).  Plays a crucial role in virion assembly and budding.  Forms a shell at the inner face of the plasma membrane and concentrates the HN and F glycoproteins.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: DAPD_TOLAT
Sequence: MSDLQHIIDDAFERRDSITPNSVDPIVREAVLQTIDMLDAGQIRVAEKIAGEWVVHQWVKKAVLLYFRINDNAVLQGAGTQYYDKVPLKFADYTPERFKQESIRVVPPATVRKGSFIARNAVLLPSYVNIGAYVGEGSMVDTWATVGSCAQIGANVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGVIVGEGSVISMGVFIGQSTRIYDRETGEIHYGRVPPGSVVVSGSLPSKCGKYSLYAAVIVKKVDAKTRSKVGINALLRSIDD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y545_CALBD
Sequence: MIVTTTPSIEGKKIVEYKGIVSSEVIVGVNLVKDFIASITDIFGGRSGTYENELIRAREEALQELQNRAAMLGANAVVGIDIDYEVLGANGSMLMVSVTGTAVVVE
What are the official names of this protein?
UPF0145 protein Athe_0545.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ADE_RHILW
Sequence: MTLHLKKVELHCHLEGAAPPELTAAQARKYGVDISGELRGGAYVWHDFASFLECYDKVSEVYRTEEDYARLTETYLDELAGINTIYSELIVSPDHGKRIGLGADAYISGICEGIRRAREKSGIEARLIVTGERHFGPESVIGAAEYAAKAGNPLITGFNLAGEERMGRVADYARAFDIARDAGLGLTIHAGEVCGAFSVADALDAVHPSRIGHGVRAVEDVDLVKRLADLGTVLEVCPGSNIALGVFPDFASHPLRRLKEAGVRVTISSDDPPFFHTSLAREYELAAEAFGFSDAEIDAMTRTAIEAAFVDEETRKALLARL
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: MURB_PELUB
Sequence: MSIEEIRKFSNEISSKINFDYDLKKSNWFNIGGQTKVYFRPDNLPDLILFLKKFGEKEKIHILGAGSNTLISDEKFDGVVIKLGKNFSNISILPNDVIIAGSACLDKKLSDFALNNGIGGFEFLACIPGTIGGGLKMNAGCFNKEFKDVLVSIQAIDKNGQVFTIPASKVIFKYRSNDLKEDLIFLSASFKGTKKNKEEIENEVLELKKKKDKAQPTKLKTSGSTFKNPIDQTDKKVWKLIKDSVPLDISFGDAHISNKHCNFFVNKNNASFEDMNKLIEFVKISVEKKTGIVLEKEIKILK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SE1L2_MOUSE
Sequence: MNPLALLVEILIIIEVTTKNTEAERYNRKQKEVNVTTQVSVSKVKQFLLYLLEQGNANKITNKRENPLEKKKHQHKLKIKGIQNKNLLKRNQNYFKNPAKKSITDEGDELFKMGNKILQESKSQKQKTEAYTLFTRAANMGNLKAMEKMADAWLFGSFGMQNITAAIQLYESLAKEGSYKAQNALGFLSSYGIGMEYDQAKALIYYTFGSAGGSMMSQMILGYRYLSGINVLQNCEVALNHYKKVADYIADKLEKSEGIPVEKVRLTERPENLSSNSEILDWDIYQYYKFLAERGDVQIQVSLGQLHLIGRKGLDQDYSKALYYFLKAAKAGSANAMAFIGKMYFEGNAAAPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPVNYGEALKYFQKAAEKGWPNAQFQLGFMYYSGSGVWKDYKLAFKYFYLASQSGQPLAIYYLAEMYATGTGVLRSCRTAVELYKGVCELGHWAEKFLTAYFAYKDGDIDSSLIQYALLAEMGYEVAQSNSAFILESKKAKILGKEKLYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYETAATHYSIAADKHHSAQAMFNLAYMYEHGLGIAKDIHLARRLYDMAAQTSPDAHIPVFFALMKLETMHLLHDILFFNFTMKWKWLKLDSTVGPYWDLLVIGLIVAMLIFLLRNRHR
What are the official names of this protein?
Protein sel-1 homolog 2, Suppressor of lin-12-like protein 2, Sel-1L2.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLE19_ARATH
Sequence: MKIKGLMILASSLLILAFIHQSESASMRSLLMNNGSYEEEEQVLKYDSMGTIANSSALDSKRVIPTGPNPLHNR
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.  Represses root apical meristem maintenance.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 19, AtLLP1, Protein EMBRYO SURROUNDING REGION 19.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE19p]: Secreted, extracellular space.
Protein: RLME_BORGP
Sequence: MYHLGDEYSQKAKREGYLARSVYKLIEINEKFSLFSSGNVLDIGASPGSFSQYAYKKLKRGVLVSVDINDISLRYVNNFYFIKGDIFSDDTASKINKFGPYSLVISDVAPKTTGNRLVDTSNSFNLNMRIIDLSFEVLLKKGNLLVKVFQGGDEMQIFKKFEKYFKFVKKIRPKAVRKNSFEIYFLGKSFGK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_SALPK
Sequence: MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFVVVSWSSHLIHGERKVVGQKGTKK
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LACA_STAAC
Sequence: MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: YPT1_PHYIN
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLHEIDRYACENVNKLLVGNKSDLTAKRVVSTDAAKEFAESLGIEFLETSAKNAANVEKAFMMMAAQIKKRMANAPVAPKAGVKLTPGQQVPSNGGSKCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  YPT1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi.  Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.  Also involved in the recycling of membrane proteins.
What are the official names of this protein?
Ras-like GTP-binding protein YPT1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasm. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side.
Protein: PGLR3_XENRU
Sequence: GMASKAGTIVGKIAKVALNAL
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Peptide PGLa-R3.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_YERPP
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKSRSRLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TRI1_STRCO
Sequence: MGVTQPAAPAYLRFPHPHGELVAFTAEDDVWLAPLDGGRAWRVSADNVPVNHPRISPDGTKVAWTSTRDGAPEVHVAPVEGGPAKRLTHWGSIRTQVRGWTADGRVLALSTYGQASLRRSWARALPLDGGPATTLPYGPVGDVAQGPHTVLLSAPMGREAAWWKRYRGGTAGKLWIDREDDGEFVRLHDGLDGNIEYPFWVGDRIAFLSDHEGTGALYSSLADGSDLRRHTPVDGFYARHAATDGSRVVYASAGELWTLDDLDGAEPRRLDIRLGGARVDLQSYPVNAARWFGSASPDHTARGSAVAVRGGVHWVTHRSGPARALAATPGVRNRLPRTFRVDGEEWVVWVTDAEGDDALEFAPATGLAPGATARRLAAGQLGRVLHLAVAPDGSRVAVASHDGRVLLVERESGEVREVDRSEDGDASGLVFSPDSSWLAWSHPGPEPLRQLKLANTTDLSVSEATPLRFKDYSPAFTLDGKHLAFLSTRSFDPVYDEHVFDLAFVEGARPYLITLAATTPSPFGPQRHGRPFETPDREETPDSEGTPTTRIDIEGLADRIVPFPVEAARYSRLRAAKDGVLWLRHPLTGVLGASRANPEDPDPNTELERYDLAQQRVEHLGGDADHFEVSGDGKRVLLWTDGRLKVVPSDRRASGDEDSDTNITVDLGRVRQTVEPAAEWRQMFDETGRIMRDHYWRADMNGVDWDGVLDRYRPVLDRVATHDDLVDLLWEVHGELGTSHAYVTPRGGHGSGARQGLLGADLSRHEDGAWRIDRVLPSETSDPDARSPLAAPGVAVRAGDAIVAVAGQAVDPVTGPGPLLVGTAGKPVELTVSPSGGGEVRHAVVVPLADEEPLRYHAWVADRRAYVHEKSGGRLGYLHVPDMQAPGWAQIHRDLRVEVAREGLVVDVRENRGGHTSQLVVEKLARRIVGWDLPRGMRPTSYPQDAPRGPVVAVANEFSGSDGDIVNAAIKALGIGPVVGVRTWGGVIGIDSRYRLVDGTLITQPKYAFWLEGYGWGVENHGVDPDVEVPQRPQDHAAGRDPQLDEAIALALAALEETPAKTPPSLP
What is the function of this protein?
Degrades oligopeptides in a sequential manner.
What are the official names of this protein?
Tricorn protease homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPEL4_RAT
Sequence: MPSCDPGPAPACLPTKTFRSYLPRCHRTYSCVHCRAHLAKHDELISKSFQGSHGRAYLFNSVVNVGCGPAEQRLLLTGLHSVADIFCESCKTTLGWKYEQAFETSQKYKEGKYIIEMSHMVKDNGWD
What are the official names of this protein?
Protein yippee-like 4.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATPB_ARAHI
Sequence: MRINPTTSDPEVSIREKKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTLGQEINVTCEVQQLLGNNRVRAVAMSATEGLKRGMDVVDMGNPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHKSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQQVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGEFDSLPEQAFYLVGNIDEATAKATNLEMESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CD59_AOTTR
Sequence: MGIQGGSVLFGLLLVLAVFCHSGNSLQCYSCPYPTTQCTMTTNCTSNLDSCLIAKAGSRVYYRCWKFEDCTFSRVSNQLSENELKYYCCKKNLCNFNEALKNGGTTLSKKTVLLLVIPFLVAAWSLHP
What is the function of this protein?
Potent inhibitor of the complement membrane attack complex (MAC) action.  Acts at or after the C5b-8 stage of MAC assembly.
What are the official names of this protein?
CD59 glycoprotein, MAC-inhibitory protein, MAC-IP, Membrane attack complex inhibition factor, MACIF, Protectin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CASK_CAVPO
Sequence: MMKSFLLVVNIVALTLPFLAAEVQNQEQPACCGNDERLFEQKKVLYLLSYPVLNNYLRTAPSYYQNRASVPINNPYLCHLYYVPSFVLWAQGQIPKGPVSTDIHQSTMQYHQAKHPSFMAILSKKILGKATILSTDAIAAPEQTPVSAAQPTVSAGDTPEVSSQFIDTPDTSVLAEEARESPEDTPEISEFINAPDTAVPSEEPRESAEDTPEISSEFIFSPETSTGPAIASMA
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF2_CAMFF
Sequence: MDSYEYTELLKKLNTKVQNISRVIKPQDIEIRLKEIEDIENRPEFWNDIKKASEIGKEKTKISNMLCKFKNVKSAISDAYELYELANAEDDEQTINSLFEDAQNLENKITNLEISMMLSGEDDSKNAIVSIHPGAGGTESNDWASMLYRMYLRFCEREGFKVETLDFQEGDEAGLKDVSFIVKGENAYGYLKAENGIHRLVRTSPFDSAGRRHTSFSSVMVSPEVDDDIAIEIEEKDLRLDYYRASGAGGQHVNKTESAVRITHIPTGIVVQCQNDRSQHKNKATAMKMLKSRLYEFELMKQQEANNAIEKSEIGWGHQIRSYVLFPYQQVKDTRSGEAYSQTDAILDGDIKKIIESVLISQKSSANKE
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_BRADU
Sequence: MRAKPSDAKLTGLFLDMLAAEQGAGPNTLDAYRRDLTDFSEFLGRVGHSFADAETQTLRDYLADLDTRGFKSTSVARRLSAMRHLYRFLLNERIRGDDPAAILSGPKRGRGLPKVLSIADVDRMLRRARELSEAEDASPSKRLRALRLYCLLEVLYATGLRVSELVALPRTAAKRDARMIVVRGKGNKERLVPLNEASRQAMADYLAATEAAKSDKKTGVAASKWLFPSFGESGHLTRQHFARDLKELAVASGLQARLVSPHVLRHAFASHLLHNGADLRIVQTLLGHTDISTTQIYTHVVEERLKSLVRDLHPLAEK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_HERA2
Sequence: MAVSEQTVARAASLRDELNLYNHHYYTLDAPLVSDAQYDSLLNELRAIEAEYPELRTPDSPTQRVGSAPLSKFPKVQHPVPMLSLGNAFNADDLAAWRRRAEQIIGTQPMSYTVEPKIDGLAVALTYINGVFSVGATRGNGEIGEDITANLRTIRDVPLRLQPIDGQALPERIEVRGEVYLPIESFNQLNERQAHAGEKVFANPRNAAAGSLRQLDSTITASRPLRFFAYAVGPFSGVELKSQAQTLDTLRTYGFSVNPDTRLFADFEAVIEYCHEWMSRRESLSYEVDGVVVKINDFAMQRELGVVGRDPRWAIAYKFPAREETTTLLNIVINVGRTGKLIPNAVLEPVSLGGTTVQHASLHNADYIISRDIRIGDRVVVKRAGDVIPYVIGPIVEARTGDERVWPAPTHCPTCGQPVEQIGDEVDIYCVNNTCPARLIRSIEHWVSRGAMDIVGMGERQASQFVEMGLIKSIPDIYRLTVDSFGGREGYGERRVANLLNAIEESKRRPLDRVITALGINGVGTVAAADLARYFRSLPALAQATIEQLTAIEGIGGSTAQSVVDFFNTPANQQLIAELLALGLKAEPSEVAELQSDRLAGKSFVITGTLPGISREAAQALIEAHGGKVGGSVSKKTDYLLAGEAAGSKLTKAQSLGVKVLSMDELHALLVDE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GRIA1_MOUSE
Sequence: MPYIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL
What is the function of this protein?
Ionotropic glutamate receptor.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
What are the official names of this protein?
Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Postsynaptic density membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Presynapse. Synapse. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. Colocalizes with PDLIM4 in early endosomes. Displays a somatodendritic localization and is excluded from axons in neurons (PubMed:18341993). Localized to cone photoreceptor pedicles (PubMed:28334377).