PharMolix/UniProtQA huggingface dataset:
Protein: COX2_CHLAE
Sequence: MAHPVQLGLQDATSPVMEELITFHDYALMTISLISFLVLYALFSTLTTKLTNTNITDAQEMETTWTILPAVILILIALPSLRILYLTDEINNPSFTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLNPGDLRLLEVDNRVVLPIEAPVRMMITSQDVLHSWTIPTLGLKTDAVPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVAELIPLKIFEMGPVFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RAPZ_SERP5
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPQLANTLAERNSSAAVSIDVRNMPESPEVFEYAMTQLPDSFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDEESDLLEPLRSRADLIIDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVASFLDRHTEVHNFIYQTRSYLEQWLPMLETNNRSYLTVAIGCTGGKHRSVYVAEQLADYFRSRGKNVQSRHRTLEKRKQ
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: CAMAU_SCOPA
Sequence: GDCLPHLKLCKENKDCCSKKCKRRGTNIEKRCR
What is the function of this protein?
This toxin stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (48%-60% of the full conductance state) (PubMed:10713267, PubMed:12869557, PubMed:27114612).  Furthermore, it triggers calcium release from sarcoplasmic vesicles (6. 6 nM are enough to induce a sharp release, and 60% of the total calcium is released after toxin (100 nM) addition) probably by acting as a cell-penetrating peptide (CPP) (PubMed:27114612).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 (EC(50)=12. 5-26. 4 nM) (PubMed:12869557, PubMed:17291197, PubMed:17888395, PubMed:27114612).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:27114612).  It binds a different site as ryanodine (PubMed:10713267).  It acts synergistically with caffeine (By similarity).  In vivo, intracerebroventricular injection into mice causes death (PubMed:10713267).
What are the official names of this protein?
Maurocalcin, MCa, Maurocalcine.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FBP12_HUMAN
Sequence: MIDQLQGTWKSISCENSEDYMKELGIGRASRKLGRLAKPTVTISTDGDVITIKTKSIFKNNEISFKLGEEFEEITPGGHKTKSKVTLDKESLIQVQDWDGKETTITRKLVDGKMVVESTVNSVICTRTYEKVSSNSVSNS
What is the function of this protein?
May play a role in lipid transport.
What are the official names of this protein?
Fatty acid-binding protein 12.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: YFH7_YEAST
Sequence: MVDTHKLADDVLQLLDNRIEDNYRVCVILVGSPGSGKSTIAEELCQIINEKYHTFLSEHPNVIEVNDRLKPMVNLVDSLKTLQPNKVAEMIENQGLFKDHVEDVNFQPVKYSALTSNNEECTAVVARGGTANAIRIAAVDNPVNVNKLAQDSINIAQIVPMDGFHLSRRCLDLFKDPQTAHKRRGSPSTFDSNNFLQLCKILAKTSLCKVSSHHKFYSTSSVFEKLSKTFSQTIPDIFVPGFNHALKDPTPDQYCISKFTRIVILEGLYLLYDQENWKKIYKTLADTGALLVYKIDIDYEATEERVAKRHLQSGLVTTIAEGREKFRSNDLLNGRDIDNHLIKVDNIVHIRND
What is the function of this protein?
ATP-dependent kinase that could be involved in endoplasmic reticulum membrane assembly.
What are the official names of this protein?
ATP-dependent kinase YFH7, Altered inheritance of mitochondria protein 12.
What is the protein family that this protein belongs to?
Belongs to the YFH7 family.
Protein: NQOR_ECO55
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: CH60_THISH
Sequence: MSAKEVRFSDDARSRMVRGVNVLANAVKVTLGPKGRNVVLEKSFGAPTVTKDGVSVAKEIELEDKFENMGAQMVKEVSSQTSDIAGDGTTTATVLAQAIVREGMKSVTAGMNPMDLKRGIDKAVIAAVEELKKLSKPCTDSKAIAQVGTISANSDESIGQIIADAMAKVGKEGVITVEEGSSLENELDVVEGMQFDRGYLSPYFVNNQQNMSAELDDCFVLLYDKKISNIRDLLPVLEGVAKAGKPLLIIAEDIEGEALATLVVNTIRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGQVISEEVGLSLEKASLDDLGQAKRIVVTKENSTIIDGAGKPDEIKGRVEQIRAQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALQALKSLKGANHDQDIGIAIARRAMEEPLRQIVSNCGEEPSVVLNNVVEGKGNYGYNAATGEYGDMIEMGILDPTKVTRSALQNAASVSGLIITTEAMVAELPKKGDSAPAGGGMGDMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN32B_HUMAN
Sequence: MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD
What is the function of this protein?
(Microbial infection) Plays an essential role in influenza A and B viral genome replication (PubMed:33045004, PubMed:31217244).  Also plays a role in foamy virus mRNA export from the nucleus to the cytoplasm (PubMed:21159877).
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, Putative HLA-DR-associated protein I-2, PHAPI2, Silver-stainable protein SSP29.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cytoplasm. Note=Accumulates in the nuclei at the S phase. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Lacks a nuclear localization signal.
Protein: RL31B_STAEQ
Sequence: MKQGIHPEYHKVIFLDTTTNFKFLSGSTKTSSETMEWEDGNEYPVIRLDVSSDSHPFYTGRQKFAAADGRVERFNKKFGLKSNNN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: HEM3_CAMJR
Sequence: MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTKELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAKIGTTSLRRKMQLLLLRPDLDIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVNFVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELLKKAESMI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CTC_BACSU
Sequence: MATLTAKERTDFTRSSLRNIRTSGHVPGIIYGKDTGNKPVSLDSVELIKTLRDEGKNAVITLEVSGEKHSVMVTDLQTDPLKNEITHADFQVVNMSEDIEVEVPIHLTGEAIGVKNGGVLQQPLYALTVKAKPKAIPQTIEADISSLDVNEVLTIADLPAGGDYSFNHESDEVVASILPPQQQEAAEVDEEESADAQPEGENEQ
What is the function of this protein?
Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions.
What are the official names of this protein?
General stress protein CTC, 50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: YG51_YEAST
Sequence: MSSAKTFTKHISFDDLAPSLIDDQATIIKNDSHHVGLNNHFLHIPPQFNPVYKNTLTGSHGSNDLATDESLDSPEDEEASSPLQLGTPTSTTSGVPHFYTQVFSPAAHDPSKSYLRSPSVERSRSESPMFRSRRRTSVRLPPPPKVSVLKKSRKAADEQGPIDDIDIGDLDFELERKMTKMTERNTQKNSGSRKGYTQAAFANLNEVEDRIETKSMVDLSESENMESSKKRSKSFAGMTDEELAKLEEFYISKGRSNKTKIDQFDFGEQVPVYLNTTESKTDSSNVTDPLAAIYPSRPTIVHNAISMTIDHPDYENYISNTKEKLNCKDKDDDVDLRVVSCYISGRRYTWSSVDWYVENLTRNGDHLVIITTIPEFEAKIDTLAYKEKRRHRLERMTSNTSESMTTASHSLIGPDLSSPLSTGIRIEAIHNEAKQTCSDILNYYARRLATKIVRISIEMVKENSTRSAIISATSLYRPSLQVISTVSANIQIKFRNGKVKLPFFLMKHFAMPAFVVPFEFIKPELLIKPRVDKDEQDNSDDLKTEVRKKERLQWLSALIRRTLENPFTKHKVVDSDDEESDSDESVTSVNEYFPISPEKKEEMEFFDKMGYVRPKPSRQVLLDDNTLMKYDSSGRKLTPIESRNSRRSSKRSSRIQFNNNGIYKVKSMVDDIYNHETASTPHIKTALKWDNEDPKMKFTSHPMRKTKSAGLSPRTSSTSSSSGQRKAHHHHHHHNHVSRTKTTESTKSGNSKKDSSSSSTNDHQFKRSEKKKKSKFGSIFKKVFG
What are the official names of this protein?
Uncharacterized protein YGR237C.
Protein: RP18_VACCC
Sequence: MSSFVTNGYLSVTLEPHELTLDIKTNIRNAVYKTYLHREISGKMAKKIEIREDVELPLGEIVNNSVVINVPCVITYAYYHVGDIVRGTLNIEDESNVTIQCGDLICKLSRDSGTVSFSDSKYCFFRNGNAYDNGSEVTAVLMEAQQGIESSFVFLANIVDS
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 18 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: PURL_LEPBJ
Sequence: MEKDVVSLQDALEHGLTAEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSVLKLKTLPTSSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPRNKYLLSRAVKGIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGIVRHDQMASATTGGQVGNAVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLLMEASLEAIQKGLLIGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEVMLSESQERMLVVPKKGKESELVSIFEKWNLNAVRIGEVTADGFIEIYMGGKLKAHIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPNSILDITPGANTKDVLLNILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSSIPDTNKALATATDCNSRYTYLDPYKGAQFAVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYMFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMVGILQDKKKFLSNFPKEVGIELAVLGNFRPSLGGSEYLKKIHGQVNGSIPEIDIKEELELCKLILSLNEKGALKSARDLSLGGIGIALSKTILFSGLGIDAELIAFKQSRLDLTLFGESSTTVLVGFDSSWKEKIREQTEEKGLKFYPVGKTTSSELLKLKDIGVEVSFSELNGPYEKGLEVVFAL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGL5_GEOSE
Sequence: EFGSYVYLGEMITNIPFPPDSPIEDRCGSCNICVDSCPTGALVQGGQLDSKKCIAFLTQTKGFLPDEYRGKIGNRLYGCDTCQLVCPENKGKDFHIHSEMEPDPEIAKPKLKPLLHISNREFKEKFGHIAGSWRGKKPIQRNAIIALAHYKDRTALPDLIKLMHEDSRPIIRGTAAWAIGRIGDQSVLFELEKALEKEQDEEVKNEIVKGIEMLKA
What are the official names of this protein?
Uncharacterized protein in gldA 3'region, ORF5.
Protein: MRAY_RALPJ
Sequence: MLLALAQWLQNDYGFLRVFNYLTFRAVMASLTALVIGLGFGPFVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVLIGIAVSTLLWADWGNRFIWIVLLVTLGYGAIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRVLELFMEWVRSGLSLNLPAKSHLIVPFFKEISYPLGVFGFIILTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIFVAETVSVMLQVTWFKFTKKRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWVITMMLVLIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPN3_ENCCU
Sequence: MDEKECVAELVDVLSQLSSNREEAMDRYERQVFTFIRNIKPETLDSLNLESELERIAAYPVILGALFMRKEFKKIDKIVNENLLSHLIGKKRVYDYFVGLIVKFLYLARKNECQDNSALFSLLVTNKELGNEYTVSVITNCLLDMLIGNKIFQRIDNSIVTTSEQARYNYYNGIIFMVEGDYESALKCFHTCVILSTNRDLVLGAEKRVILCMLLSSDYSIPYPCKPSLRIYFKLASAVKRADIKKFEETLESNKDELMSQGLYFVAKRLSQNVIQEGIRKISVVYSRISYEDIAHILGINSGEVEYLVKRTIRKGLIKGKVADGIFYSLREDKSKTDIGIGIRDCIQLANYIQEHMRYPAIEPLCYEKVRKVHDK
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit RPN3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYI_THEAB
Sequence: MDYKETLNLPSTEFSMRANLVKKEPEMLKKWKEMDDYNLVLKSREGKPKFVLHDGPPYANGNIHIGTATNKILKDIVIRYKTMRGYYAPYVPGWDTHGLPIEHRVSVEMGEKIKEMSPVEIRQKCKDFALNFVNIQREQFKRLGVRGDWDNPYLTLDPKYETHILNIFKTLVKNGNVYRGNKPVYWCPTCKTALAEAEVEYHDHSSPSIYVKFKLIGEENTYVVIWTTTPWTLPANVAIAVHPEYDYVKIKVDGEYWIVAEGLLNKFAAETEINYEVVEKFKGKDLEYKKAKHPFIDRESLIVLADYVTLEDGTGCVHTAPGHGAEDYLTGLKYNLPVLSPVNEEGIFTEEAGKYAGLKIWDANKVIIEDLEKLGALIKTQKIEHSYPHCWRCKNPIIFRATPQWFISVDKNNLREKVLEEIKKVEWHPKWGENRITAMVKERPDWTISRQRVWGTPIPAIKCKHCGEVFIDEKVIDSFITIVEKEGTDAWFKLPEKEIIPEDVKCPKCGHNEFEKTYDTLDVWIDSGCSFEAVIRSKGEKFPVDLYLEGDDQHRGWFQSSIFMSVAHTGQAPYKSVVTHGFIKDEHGRKMSKSLGNVIDPKEIVDKYGADILRLWVSSIDFFDNIRVGKNIIQQQVEVYKKIRNTLRFLLGNLSNFTKNDLVEFDKLLPLDKWALGRLQEVISQVTEHYEKYEFSKVYSLINRYCTVELSATYLDILKDRLYVEAKDSIYRRSAQTVMFYILDALIKMLAPVLVFTTEEAYQLSPLKEFDTVHLEYWPQVRKEFVDEKLMEEFKILFMVRDDVLKALENARKNDIIGHSLDAKVTLNGVNEQINNVLVKYKDYLEEIFIVSQVEIGEGKVKGEFANVSVEKASGEKCQRCWKYSEETGKDEEYPNTCPRCAAVLKGLRK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_PARDP
Sequence: MLLCIDTGNTNTVFSVWDGEKFVGLWRISTDHRRTADEYFVWLSTLISLQKLELNIDACIISSTAPRVVFNLRVLCNRYFDTRPLVVGKPDCLLPVAPRVDFGTVVGPDRLVNTWGAFERHGPDLIVVDFGTATTFDVVDTDGAYVGGVIAPGVNLSLEALHMGAASLPHVDVTMPAKVIGTNTVACIQSGIFWGYIGLVQGVVDKIRLERGRPMKVIATGGLAPLFDQGFDLFDAIEDDLTMHGLRLIHDYNKEMGNG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_PSEE4
Sequence: MNLFDFFRGRQKQTSASVAKERLQIIVAHERGQRSTPDYLPALQKELVEVIRKYVNIGNDDVQVALENQGSCSILELNITLPER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NDHI_TETRE
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MTFR2_RAT
Sequence: MQRDGTNEQCFLELASPMSFILNILRNMLAYFGVPVDQDLLIFQNKDYGSARSIVRVIGRMLPLEPCRRPRFELTPPANAKEVDDYELAVPSFADVLCVADDGEAGCLRFRHSLWKKAEGKAALFHPSKLPWDLSSPALSQNRTVADDLPVSEAAIKKIAALEDELTSLRAQIAAIVAMQDLGGGGETGFISLSDGPSMEQVPPSSATARLSVEPDHVPSVVLSPPPLPPPPPPLPPPQFSLQPPSSLPVPPGSANTRGIDNLAAEMKKRPSGVKKTDGSHHSESQRVSDVPNMLDVLKDMNKVKLRPVERSPGGRPIQKRRRQSSQWDPVSLISNALKQKFAFQDDSFDSENRSWQGSPFSSPETSRNGSRF
What is the function of this protein?
May play a role in mitochondrial aerobic respiration essentially in the testis.  Can also promote mitochondrial fission (By similarity).
What are the official names of this protein?
Mitochondrial fission regulator 2.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Associated with membranes.
Protein: MAL33_YEAST
Sequence: MTLVKYACDYCRVRRVKCDGKKPCSRCIEHNFDCTYQQPLKKRGSKPIGTRSLKYIPKAKMFIDNKSCTAAAEILMKVPKKVIDQCLRLYHDNLYVIWPLLSYDDLHKLLDEEYNDHYVYWFLVALSAANLSDLQSELESEGGFSFTGKQLAVLCMSSRQQFDDLSGRDIFRIMTYYCLLRCFSQSSDVRNSYRLCREAIGLVIVAGLHREKAYESLSFREQQLLRKVYYLLLLTERYYSVYVHCVTSLDTTIAPPQPEFVTDPRLSLDSFFEMIRVFTVPGKCFFDALATESTSGSCTEDSLKKIWKELHTASLEIEPWSYGYVDISFSRHWIRALAWKLVFQMNGTKFFSNANNAHILVEIAKDMLDDIFLTPNNLYDVHGPGIPMKSLEVANALVDIVNKYDHNMKLEAWNILCDVSKFVFSLKHCNHKMFQRFSTKCQSALIDLPISRPLRLNDDSKDEDDIIP
What is the function of this protein?
Regulates the coordinate transcription of structural MAL3S (maltase) and MAL3T (maltose permease) genes.
What are the official names of this protein?
Maltose fermentation regulatory protein MAL33.
What is the protein family that this protein belongs to?
Belongs to the MAL13 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_CLOPE
Sequence: MSRSIKKGPFVHAGLLKKIEEMNQNGDKKVIKTWSRSSTIFPQMIGHTIAVHDGRKHIPVYVTEDMVGHKLGEFVLTRTFKGHIKNEKTSKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL27_STAAE
Sequence: MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y423_METJA
Sequence: MYGIVMFVNRKEELEFLERKWNENKANLIILYGRRRVGKTMLIKKFLENKKIKRASIFC
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0423.
Protein: Y968_TREPA
Sequence: MSVSYRGPRWSSFVHVSQHSCRFVAPTCAEGAQGCSEFGAFPVFEERGMCAARRMRRAAIAACCVFARGAAANPYQQLLRHRLEALRPGARAQIEFDVAHCGYEKARLRSAGTYVLGSELEIRGHSAGDFGLPRFGIKPIIGVRSPRYNNLVVSIDTARVTSIGNISRINADIGVDLYSNVRGRELIRMRRAEHEEKAAQNGERIKSPSVELALIDELEVLFTRAQSLVRREFHMGDARLVHLRTRAAGFSEHSEKARRVRLAYDRTQREFEQEERLFAQVCDPFAAVCAVGGGDEARRDFLLQLAEAVPREVPLSLVSLHATDAHSLAAAQEMALLERAAQRSERDLYAVRVGAVVSMGTRKTFILFKGDGTESLEGSGTVALHMPSVNAQVEVKVPYAERGKHSRDKVGVYGKSQWNPLEIAYKVFERREERAQEQEQEQYCEDSLARETRKMEGLEVQGKQLFAAQETALRTREALRLDLAKVERAAARGVVGGNRLARARCEYAVAQLRAACAKLHMLRFNLGVVRAFGLVPQVAP
What are the official names of this protein?
Uncharacterized protein TP_0968.
What is the protein family that this protein belongs to?
Belongs to the TP096X family.