PharMolix/UniProtQA huggingface dataset:
Protein: NTPPB_METCA
Sequence: MPTPPPQPRPLLLASGSSYRRELLRKLGLHFTAVAPDIDEAARPGEAADDLALRLACEKALALAPAYPDHLIIGSDQVAVLGDSRLGKPGTHEKAVAQLLRASGNTVTFLTGLCVHDAVSGVSHTGLDRCHVHFRRLDRDQIERYVTADEPYDCAGAFKSEGLGIALIERFEGEDPNALVGLPLIQLTEILKRFGIAVF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UT112_PEA
Sequence: ATKGSSDNRVLTGV
What are the official names of this protein?
Unknown protein from spot 112 of 2D-PAGE of thylakoid.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid.
Protein: RIMO_DELAS
Sequence: MTPTSDATTMTTPAGAAAPRVGFVSLGCPKALTDSELILTQLSAEGYQTSKTFEGADLVIVNTCGFIDDAVRESLDTIGEALAENGKVIVTGCLGAKAGKDGGNLIQEVHPSVLAVTGPHATQEVMNAVHTHLPKPHDPFIDLVPGAFGEAGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVGDVLKEARALFEGGVKELLVISQDTSAYGVDVKYRTGFWDGKPVKTRMLELVQTLAEIAEPYGAWVRLHYVYPYPSVDEIIPFMATGRVLPYLDVPFQHSHPDVLKRMKRPANGERNLERLQRWREICPDLVIRSTFIAGFPGETEQEFEHLLQFLREAQIDRAGCFAYSPVEGAAANEIPGMLPLEVREERRARFMAVAEEVSTARLQKRVGQTMQVLVDKSVGLGKKGGVGRSYADAPEIDGLVHLLPPEKASKTYKVGDFVKARIVGTQGHDLVGQPV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_RHILO
Sequence: MSKVGNNSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKTSMVKSREGVPTPQEILKVLDDYVIGQPYAKRVLSVAVHNHYKRLAHAGKNNDVELAKSNILLIGPTGCGKTLLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTANILFICGGAFAGLDKIISDRGRKTSIGFGATVASPEDRRTGDIFRQVEPEDLLKFGLIPEFVGRLPVLATLEDLDEPALIQILTEPKNALVKQYQRLFEMENVDLTFHENALSAIAKRAIERKTGARGLRSIMEAILLDTMFELPALEGVREVVISEEVVTGSARPLYIYSEQKEKKGNVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: I11RA_PONAB
Sequence: MSSSCSGLSRVLVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGPDSGLGHELVLAQADSTDEGTYICRTLDGALGGTVTLQLGYPPARPVVSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPRQPHFLLKFRLQYRPAQHPAWSTVEPAGLEEVITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTVPKEIPAWGQLHTQPEVEPQVDSPAPPRPSLQPHPRLLDHRDSVEQVAVLVSLGILSFLGLVAGALALGLWLRLRRGGKDGSPKPGFLASVIPVDRHPGAPNL
What is the function of this protein?
Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity.  The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
What are the official names of this protein?
Interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha, IL-11RA.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
[Interleukin-11 receptor subunit alpha]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Soluble interleukin-11 receptor subunit alpha]: Secreted.
Protein: YHR2_YEAST
Sequence: MVDLSTALIHGDDKDNRVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAHPNSTRLESIFSEILDGYAVIYSSGLAAFYAAMVHYNPKKIFIGQSYHGVRAIANILTRNYGIEQHPLEDIEKCASEGDIVHLESPVNPYGTSSDIESLARRAHAKGALLIVDSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVANLESFMLLRSLRTYEMRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQTEEFVKKQLVGGYGPVFAITLYTKEQCKQLPLKLKYFHHATSLGGIESLVEWRAMTDPYIDQTLIRVSVGCESANDLIKDLASALKELQDAA
What are the official names of this protein?
Uncharacterized trans-sulfuration enzyme YHR112C.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: GACW_DICDI
Sequence: MTTPVSLSQVEKKTIESILTNKKEEGKLITKVTILNEKKKKLEIKTLILSSNRIFLFTDSKGKLSAEHHYLEITEIASQSENDVTIKFKNQNVMKMNLDASEVLKTLYGTLMSTFPGIKIGKTIIFNITPASRIPSIFQATSFKDIQGCGSFNLTYRSVCDHLGVQPLSSILWDIENLYPFNQVREFNLAEIYQYSFTDLKAILLSLSYNTYFQSFQSNGKLSNEDLNLLAEVFKENSSLQQLTITNSQASKEPIITLLQNVAENKALHLSHINLNNNSLENKGILTLGSSIQTFSNGLTYLNIENTSCSGKGLEAMFGCLTANNVVCGSMTHLNISNNKLESYGTNGLCKFLSKATALQQLLMSNTSPVYSFLKTSSSSIQTLDFSGNKSTTTKESVIDILSFFKQMSHLQTVNLSRIQTTPDDLKLLFSPATSLLKCSSVDLSENDLGDGGIIKLCEIMYPNSNLHHLSIDGNFKTKSKLRARAIEALINLIDDNTSIESLSLASGSGKYQLKGDLMPLLLSLLKNQSLVKLDISGNGVGDSGALAVSKILWKNQTLKSLKCDGNDFSYTALKMIKCSIRRNEKSLTILQLPLSDISTILKNDSNGSSHEKILKTIQDIQTSIVINYPNNIHPIDTSSGGLTPTKQPSIGSLAGVIKKPPIGPPSTPTKSSNPGFQTLPKRPTRGPLYPGRATGGAVTLTDKAQINASTIELPPLVSRSIDLLMEQGISSVGIFRTCASATALKKIKTRFEAGEDIDLKAENVDVDTVAGVLKSYFRELPNPIFPENLHEYFFQAMRQSSNEEIIQSLKDIIDQLSPLECKMIKKLFHLLHLISLEKDVNMMSPENIAICWAPTFFRSFASELLPINSFMIVNYFDIFDPENKPISSDNSGDADTDSTQSTCTTNNNNLVATSLSSPISPSTTPTKSIDNVLHTTVEVSRSPNHERAHTVGPMTSKRPISNNNGVSSNTPPLPNNVTPHHNTMPSRPSASPIKRPPSMGGSLSNFAGIPLSNHSSSGQLNNNNSNNNTTSNSSNSSSGKSSSNPSPIPTPPDSPSMSYIGDGKSTLRSKRFSRVNRVSYSPVLPRAWTNESRTVSSLFQDDLDSNSDSSGPSL
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacW, GTPase activating factor for raC protein W.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTV1_DICDI
Sequence: MPKPFIQNKNKQVLATFTASYRDRHGRETGVRDKVISEGEEDYSGEDNFSGEEEYEEYDSDDSEHDEYIQQESAKKEVDDLSTIGFKKDGFDYSKYMRPIGGGVFIPAIWDVNELKNKKNGIVELVKNSEPAPFMFGLEEISKDYKKDVKDLEVDEDIKEALVVDDEEDDFEELDDDFILQANGGTLDGLQDEVDETINKFNNFRIKNKAYDFIDDEEDYNGDGEYYEGEDDDDDYYEDDEEYYKNLKNKSGNNNNNKDDGRKVQDEVLEAQFEIALEQYEDEDIGELEPEETLGTCNVNNFEDVFDEFIDDYNKNHEPLMVQIQTLKKNNNFIALTEKEKEIILKRDWNKEVLVEVSDHENEENEDDKWDCETILTTYTNLENHPKLLREEKKIKLSRKTGMPIGVIPTKQKGDDGNSDNEEEDEEEDEKSVNLGVSRKNETKESKKLRKQQLKDDRKNKRELKKDLKVAFKKEEIKQTSIIKDQKTNSSVAVRY
What are the official names of this protein?
Protein LTV1 homolog.
What is the protein family that this protein belongs to?
Belongs to the LTV1 family.
Protein: YOKF_BACSU
Sequence: MKKVLLGFAAFTLSLSLAACSSNDSEKVSTEKETPQASTDVEKKTEQKESTKEKTADKSKEKDKKELVDVTLDRAVDGDTIKVTYNGNVDTVRYLLIDTPETKKPNSCVQPYGEDASKRNKELVNSGKLQLEFDKGDRRDKYGRLLAYVYVDGKSVQETLLKEGLARVAYVYEPNTKYIDQFKKDEQEAKSEKLSIWSKNGYVTDRGFNGCVKEKTTAVKKATTSKPAATQPTTPKASSETSTTTEKEASSETTGGTETFKNCTELRKKYPNGVPSSHPAYQSKMDRDHDNYACER
What is the function of this protein?
Catalyzes the hydrolysis of supercoiled double and single strand DNA and RNA.  Involved in chromosomal DNA degradation and cell death caused by thermal stress.
What are the official names of this protein?
SPbeta prophage-derived endonuclease YokF.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARND_AERHH
Sequence: MTEVGLRIDVDTFRGTRDGVPRLLQLLDKHQVKGSFFFSVGPDNMGRHLWRLLKPRFLLKMLRSNAASLYGLDILLAGTAWPGKSIGKQLGSLMRDTDSARHEVGLHAWDHHGWQANTGRWDEAELARQTRLGVDALNQILGREVDCSAAAGWRADPLTTQAKEPFGFRYNSDCRGSGLFRPLLQDGRPGTPQIPVNLPTFDEVVGHQVTVDDFNRFLLDQLATPPAQGQHVYTIHAEVEGIVMADQFDALLGEARARGIRFVPLGDLLPSDPTTLPTGRLVRGTLPGREGWLGCKAEA
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: IFNB3_BOVIN
Sequence: MTYRCLLPMVLLLCFSTTALSRSYSLLRFQQRRSAEVCQKLLGQLHSTPQHCLEAKMDFQVPEEMNQAQQFRKEDAILVIYEMLQQIFNILTRDFSSTGWSETIIEDLLVELYGQMNRLQPIQKEIMQEQNFTMGDTTVLHLKKYYFNLVQYLESKEYNRCAWTVVRVQILTNFSFLMRLTASLRD
What is the function of this protein?
Has antiviral, antibacterial and anticancer activities.
What are the official names of this protein?
Interferon beta-3.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: OL148_MOUSE
Sequence: MDNYTLLNEFILLGIPQTQGLETLLFVVFLFIYFFTLLGNSLIFTAIISSSTLHTPMYFFLGLLSVFDMLFPSVTCPKMLFYLSVRSPAISYKGCAAQLFFYHLLGSTEGCLYSVMAYDRYVAICHPLRYMLIMKPGVCVSLVIIAWLVGCLHATILTSLTFQLVYCASNQVDYFFCDLPAVLPLACTDSKLARKVGSINVGFLALMLLFSVCVSYVHIGVAILRIRSAEGRQKAFSTCSAHLTAILCAYGPVIIIYLQRTPNPLLGAVVQILNNIVSPMLNSLIYSLRNKEVKRSLRRVFQNITFHGQK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 148, Odorant receptor M30, Olfactory receptor 224-4, Olfactory receptor 7F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCP_THEMA
Sequence: MQMFCYQCSQTANGTGCTEYGVCGKSPTVARLQDNLVFAIKGISAYYYHARELGYDDPEIAGFLDEALYSTLTNVNFDAQSFVEYALEAGRMNLKAMQLLKKAHIETYGEPTPVEVETGTKKGKGIIVTGHNLKALEELLKQVEGTNVYVYTHSEMLPAHGYPGLRKYKNLIGNLGKAWYDQRKLFAEYPVAILGTSNCVLIPSESYRDRMFTTSIARLPGVKHIDGYDYTEVIEKAKSLPDLEEKPGSYKLRTGFSTSVVVSLADKIKELVEAGKIKHFLVVGGCDVPFKRNEYYREFVQKLPKETVVITLACGKFRINDLDLGDIDGIPRLIDVGQCNDTIVAIEIAQALAKVFGVEVTELPLTLVLTWMEQKAVAILWTLLALGLKNIYVGPVLPAWVNEDILKVLTAEFGLKTISEPEKDIKEILKV
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA5_DECAR
Sequence: MSEVNLKGRKVTVHDMCLRDGMHAKREQMSIEQMVTIATALDEAGVPYIQVTHGAGLGGNSLQHGFAPHSNEAYLAAVCGAVKQTKVSVLLLPGLGTMRELQSAYDCGARSVHVATHCTEADTSPQHIAFARKLGMDSTGFLMMAHLNTPEGLAQQGKLMESYGAQTVYITDSAGYMLPGDVKARVSALRDVLKPETEIGFHGHHNMGMGIANSIAAIEAGASRIDASVGGLGAGAGNTPLEAFVAVCERMGIETGCDLFKLMDMAEDIIFPIMDHIVRVDRSSLTLGFAGVYSTFLLHTNRVSQRFGIPARDILVELGRKKMIGGQEDMIIDTAMTMAKERGLLKDATAGVAP
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 5, HOA 5, 4-hydroxy-2-keto-pentanoic acid aldolase 5, 4-hydroxy-2-oxopentanoate aldolase 5.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: CSLD4_ARATH
Sequence: MASTPPQTSKKVRNNSGSGQTVKFARRTSSGRYVSLSRDNIELSGELSGDYSNYTVHIPPTPDNQPMATKAEEQYVSNSLFTGGFNSVTRAHLMDKVIDSDVTHPQMAGAKGSSCAMPACDGNVMKDERGKDVMPCECRFKICRDCFMDAQKETGLCPGCKEQYKIGDLDDDTPDYSSGALPLPAPGKDQRGNNNNMSMMKRNQNGEFDHNRWLFETQGTYGYGNAYWPQDEMYGDDMDEGMRGGMVETADKPWRPLSRRIPIPAAIISPYRLLIVIRFVVLCFFLTWRIRNPNEDAIWLWLMSIICELWFGFSWILDQIPKLCPINRSTDLEVLRDKFDMPSPSNPTGRSDLPGIDLFVSTADPEKEPPLVTANTILSILAVDYPVEKVSCYLSDDGGALLSFEAMAEAASFADLWVPFCRKHNIEPRNPDSYFSLKIDPTKNKSRIDFVKDRRKIKREYDEFKVRINGLPDSIRRRSDAFNAREEMKALKQMRESGGDPTEPVKVPKATWMADGTHWPGTWAASTREHSKGDHAGILQVMLKPPSSDPLIGNSDDKVIDFSDTDTRLPMFVYVSREKRPGYDHNKKAGAMNALVRASAILSNGPFILNLDCDHYIYNCKAVREGMCFMMDRGGEDICYIQFPQRFEGIDPSDRYANNNTVFFDGNMRALDGVQGPVYVGTGTMFRRFALYGFDPPNPDKLLEKKESETEALTTSDFDPDLDVTQLPKRFGNSTLLAESIPIAEFQGRPLADHPAVKYGRPPGALRVPRDPLDATTVAESVSVISCWYEDKTEWGDRVGWIYGSVTEDVVTGYRMHNRGWRSVYCITKRDSFRGSAPINLTDRLHQVLRWATGSVEIFFSRNNAILASKRLKFLQRLAYLNVGIYPFTSLFLILYCFLPAFSLFSGQFIVRTLSISFLVYLLMITICLIGLAVLEVKWSGIGLEEWWRNEQWWLISGTSSHLYAVVQGVLKVIAGIEISFTLTTKSGGDDNEDIYADLYIVKWSSLMIPPIVIAMVNIIAIVVAFIRTIYQAVPQWSKLIGGAFFSFWVLAHLYPFAKGLMGRRGKTPTIVFVWAGLIAITISLLWTAINPNTGPAAAAEGVGGGGFQFP
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein D4, AtCslD4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: EAA4_CAEEL
Sequence: MAKLSKENLLLLFTVLGVVVGIGLGFSLRDPSKAWSKRHLSYLRFPGDLFVQMLKMLILPMIMSSIITSLASLDSGTAGRLGMVSMIYYTLTTFFAVFLGIVLVSVIKPGKWTTTNIEDLVGHVKTTPCVATAVDTIIDLMKSCFPENLIEATFRSQKICLKFFNGTTEIPPEIAMTMSPEQRAQFTEVPEKIVSDGMNILGLVVFSVALGIVIGVIGEDGKPMKNFFKSLEACSMKLIGWVIIYSPVGITFLIAAQIVGMKDPGQELHRLMGYVITVILGLLIHAFVVIPLLCVVLARRNPIKFVGGMAQALLTALATSSSSATLPLSIKCCEENNKVDPRVTRFVLPLGATINMDGTALYEAVAAIYISQCYGNDLSLGEVVLVSLTATLASIGAAGIPQAGIVTMIMVLIAIGLPTNLFILIFPVDFMLDRLRTTVNVHGDSIATAVIERLCEDQLQKGGHHLDTNDQGYSMLSTNASPDPKRITIGNNCENSHML
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate.  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion.  Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport.
What are the official names of this protein?
Putative sodium-dependent excitatory amino acid transporter glt-4.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRB_LEPBL
Sequence: MASIFKIHSAYKPAGDQIKAIENIADSFQKGAEKVTLVGVTGSGKTFTMAQVIQNLGLPTLVLSHNKTLAAQLFREFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDSSINEEIDKLRLRATSSLLEREDVVIVSSVSCIYGLGSPEEYTNSVVALKTGDTIERDAVIRKLLHIQYNRNDIDFSRGNFRVRGDSIEIYPAYHTDGIRIEFFGDEIDSISRINPITAQTILKLEKTYIYPAKHFITSGPKVKVAIENIKAELEAQALFFRKNDKLLEAERIISRTNYDMEMLQEMGYCNGIENYSRHLTGRKAGERPACLIDYFQGEFLLIVDESHVTIPQIGGMFAGDKARKQTLVDFGFRLPSALDNRPLNFEEFETLTPKTLYVSATPADYEMEKSSKVVEQIIRPTGLLDPIVEVRSTKNQIEDLLVEIRKRIDVGERILITTLTKKMSEDLTDYYKEIGLQVAYLHSEVETLDRVAIIRDLRKGIYDVLIGINLLREGLDIPEVSLVAILDADKEGFLRNYKSLIQTVGRAARNVNGTAILYADKITDSMAKAIDETKRRRKIQEDHNLKFGITPLTIRKEVNDIIEREEKKRTSEDLVLEDVEKKFNSKKFPNKEVLKDKLREEMMKAAKELDFERAAILRDKMLSIQINDPSTEN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_JANMA
Sequence: MQLLAVGLNHTTAPVSLREKVAFPADQLGQAVASARSWYGRSDATTYTDEAAILSTCNRTELYAASNLPGGVNEAIDITAHFLADYHKLPYAELRPYLYALPQDNAVRHAFRVASGLDSMVLGEPQILGQMKDAVRQAEAAGGLGTYLHQMFQRTFAVAKEVRSTTEIGAHSVSMAAASVRLSQRIFDKISEQNVLFIGAGEMIELSATHFAAQNPKSVTIANRTLERGQTLAHRFNGKAIRLADLPDQLASYDIVISSTASSLPIIGLGMVERAIKARRHKPMFMVDLAVPRDIEAEIGRLDDVFLYTVDDLGSFVQTGVENRQAAVAQAEAIIETRVRSFMHWIDARAVVPVIQDLHESSETMRMIELERARKLLAKGEDIDAVLEALSKGLTAKFLHGPQQALNNAQGDERARLAALLPQLFRTKR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SYA_STRT2
Sequence: MKQLTSAQIRQMWLDFWKSKGHAVEPSANLVPVNDPTLLWINSGVATLKKYFDGSVIPENPRITNSQKAIRTNDIENVGKTARHHTMFEMLGNFSVGDYFRDEAIEWGYELLTSPEWFDLPKDKLYMTYYPDDKDSYNRWIACGVEPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEEFDPDNIGIRLLEEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREIEKMSGKAYDPDGETLSFKVIADHIRSLAFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGISDAFLYKLVPTVGQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSSMLDELLANLKKSGKDTLEGKDIFKLYDTYGFPVELTEELAEDEGFKIDHEGFKAAMKEQQDRARASVVKGGSMGMQNETLANITEPSEFLYEAETAESRLSVIVADDARHDSVNSGQALLVFEQTPFYAEMGGQVADHGTISDAAGTTVARVVDVQRAPNGQALHTVEVEGELVVGANYKLEIDHSRRHRVMKNHTATHLLHAALHNIVGNHAVQAGSLNEQEFLRFDFTHFEAVTPEELRAIEEQVNEEIWKATPVTTIETDIDTAKSMGAMALFGEKYGKRVRVVSIGDYSVELCGGTHVANTAEIGMFKIIKEEGIGSGTRRILAVTSREAYLAYREEEDALKSIAATLKAPQLKEVPNKVASLQEQLHALQKENATLKEKAAAAAAGDVFKDVKEANGVRYIASQVEVSDAGALRTFADQWKQADYSDVLVLAAHIREKVNVLVASKSENVHAGNLIKVLAPIVSGRGGGKPDMAMAGGSDANSIQDLLSAVAEQF
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA2_LACDA
Sequence: MAKIGVLGAGTWGMALARMLSNSGHEVTVWSALPQEVDELSRTRRQKNLPGMVIPDEIKFTKEIAEACQDKDIILFAVPSVFVRSIAKTAAAFIPDGQIIVDVAKGIEPDTLLTLTEVIADELNKDGKHGNVHYVAMSGPTHAEEVAKDLPTTIVSACEDQAVAKKVQDVFMNKNMRVYTNSDRLGVELCGALKNVIALASGICSGLGYGDNMRAALIIRGMAEIKRLGLKMGGKEDSFDGLAGMGDLIVTATSKESRNNNAGYLIGKGKSAEEAKKEVGMVVEGINAIPAALELADKYDVEMPIVFAVDAVVNRGADARETVDALMLREKKSEMTK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+] 2, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRD1_DROME
Sequence: MQLLLSSVCMALTSAVIGFAYYQKQQFYPAVVYITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDFNPRFVALFTVLLFLKSFHWLAEERVDFMERSPVLGWLFHIRVGSLLTVLGILDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTVIASTAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIMSRRAIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVNVAGGQALPPNFADLFGDASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGYLTPLPPPPIPQDLTNFTDEELRAMEGLQRDHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLTAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMPAEKVTIEDLGADADEDDIPSTATEAVSIPNSDADFEENSSELGELRKRRLKFLEERNKSAATNERTTAE
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation.  Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Also promotes the degradation of normal but naturally short-lived proteins.  Protects cells from ER stress-induced apoptosis.  Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase HRD1, RING-type E3 ubiquitin transferase HRD1, Septin-interacting protein 3, Synoviolin.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NADE_ECOHS
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RS16_DEIDV
Sequence: MVKIRLSRFGSTHNPHYRIVVTDARRPRDGGYIENLGHYDPRKTTETYLKVNTERAAYWLAQGAQPTQTARRLLKAQGVKVA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RSMH_HAEIN
Sequence: MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIEHNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDFNKSAVKNGTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDMLAPEGRLSIISFHSLEDRMVKHFMKKQSKGEDIPKGLPLREDQIQRNQKLRIIGKAIQPSDAEIQANPRSRSAILRVAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SYNY3
Sequence: MTKKLSKRMQAAIAKVDDSKLYSPLEAMELLKETATAKFDETAEAHIRLGIDPKYSDQQIRTTVSLPKGTGQTVRVAVLARGEKVKEATDAGADIAGSEELIEEIQKGMMDFDVLIATPDMMPKIARLGKQLGPRGLMPSPKGGTVTADLAAAVNEFKAGKLEFRADRTGIVHVMFGKASFSADDLLANLKALQETIDRNRPSGAKGRFWRTVFVSSSMGPSIPVDINALRDLKFEDN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LAPB_HAEIN
Sequence: MIELLFLLLPIAAAYGWYMGRRSAKKDQDDISNKLSRDYVTGVNFLLSNQTDKAVDLFLDMLQKQEIENEIESHSQFEAELTLGNLFRSRGEVDRALRIHQALDLSPNYTFEQKLLAKQQLARDFMVVGFFDRAENLYILLVDEPEFAENALQQLLVIYQKTKEWKKAVNIAEKLAKIKPQENNIELAQCYCEYSQSLEPESAVEKRSVLQKALSVSPTCVRASLLLANLAMLDGQYQQAVKILENVLEQNPDYTGEILLPLKHCYEELNQLDNFELFLIRAGQIINNDEVELALAKLIEEKDGKSAAQAKLYQQLTKKPSTLIFHRFMQYQIDDAEDGRGKESLILLHKMVGERIKQTSPYRCTNCGYQIHKLLWNCPSCRQWESIKPVSNQEHN
What is the function of this protein?
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis.  May act by modulating the proteolytic activity of FtsH towards LpxC.  May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.
What are the official names of this protein?
Lipopolysaccharide assembly protein B.
What is the protein family that this protein belongs to?
Belongs to the LapB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.