PharMolix/UniProtQA huggingface dataset:
Protein: PDRP_BRUO2
Sequence: MTRPLSYFHLHLISDATGETLLAAGRAAAAQYANARAIEHIYPLIRTEKQLRKVLEGIDAEPGIVLYTVVDQKLAAIIDESCADMGVPSVSVLEPVLNTFQSYLGAPAHRRASAQHVLNADYFRRIDALNFMMEHDDGQLPLDIEEADVIIVGISRTSKTPTSIYLANRGIKAANVPLVLGIPVPEILFAAKRPLIVGLVATAERISQIRQNRPLGNIPSLDTGLYTDRVSISEELAYARNLCNRHGWPIIDVSRRSIEETAAAILALLRNGKKEGSSS
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: Y1084_STRS2
Sequence: MYQIEFKEEAFLPRERLVEVGAERLSNQELLAIFIRTGTKKEPVSILSNKLLNRLESLAALRELSIEELQSLTGIGRVKAIEIKAMIELGKRINQSELLLNERILGSEKLGRKMIHEIGHKKQEHLVALYLNTQNQIISQKTIFIGSVNRSIAEPREILHYAVKCMATSIIIVHNHPSGSVQPSRNDLLFTENLKESCEKLGLVLLDHLIVGNKDYYSFREESDVILKFIDNIVEEVFFNLTFTVE
What are the official names of this protein?
UPF0758 protein SSU98_1084.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: TAL_CLOBH
Sequence: MKIFIDTANVEEIRKASELGVLSGVTTNPSLIAKEGRDLKEVVEEICNIVDGPISAEVISLEYEKMIEEGRELSKLHKNIVIKIPMCEEGLKAVSVLSKEGIKTNVTLIFSSMQALLAARAGATYVSPFLGRLDDIGNPGIEVVEQIADMFKIHEIKTEIIAASVRTPMHVLEAAMAGSHIATIPYKVIIQMSKHALTDIGIEKFMKDYEKAFGENK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORC2_DICDI
Sequence: MEEYTDSGEDKNVYSDDDNDYFTASTQNNRTSKNTDSSPLDPKRLAEEMSKIQPKHEKEKKKLFESYYKTRENEENGADNHCFKFNKIYTDLKFDYSVLVSGFGSKIQLIETFVKEFCTDGPSLHFKGYLPNLSVRDLLYKITFSLFGIDKKIASPIAHCNFIKSIFESGSMDINKMRQTFGGRFDYGIPDHVYVVIHNIDGYSLRNETSQLTLALLATIPQVHMIATIDAIGAQLLWDNRMLSNFNWTTYSMPTYQPYDLELSYDTNTKGGGGGGGIGSKSSSGTNKNLQPSTILTVLKSLTEISTDIFKELLTYLIKKKKNKMEFKILFDICRDAFLVSSESGLKTQLREFIDHKIIIQKEIGDTTFLIIPIETSVMEIILSQLENSIS
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 2, Origin replication complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the ORC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FHKB_DICDI
Sequence: MSQDIQTQNSYSDELYSSQIYSTQQPQQPQQQPQQQQSTFSSQQSQSSSYDFIYSTPQIHSQNSQNSQFSQNPLYDDFIHSTQNSYSQRVSSQRSYSQKSSSSQISFSQIPSSQIQSSQIPSSQIHSSQIPSSQNQSSQKSQFSFSQIPSSQIPSSQKRFFQSQNDDFVPSSQVTSLQDICLPQPIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCQPQQQQTQQQQQQQQQQQQQQQQQQQQQQQQQQTQQQQQQPQEDDDDYDDYDGYDNYEDFVYNEGEEGEEDYEDYEQENDDDDDEDEDDDDDDDDDDDDEEEEEESQQQHIRSRALQSRSSQSRPLLRSGFKSPISRLSQTKTSPEYIYISSQSNTHTNQLGQSSQQTNSPNVHFNSLQQKKKQQQQQQQQQQQQQQQQQQQQQQQQQQQSQQIIGSQSSQSSQLPPTQPPVEVPVNLGRLIPINASHIPINLNLKREDRIVVGRSSSCDARLIDNYLTISGKHCEIYRADNLTCLKHIPLCKDKTDCHKNFGMLIVHDISSNGSYINGELIGNGKTRILRSDDILSLGHPSGDLKFIFESEFQFNFILDIKDNVNNLNENLDYKKLRTAYDNARIENKNCALRDYYFVKEIGSGGYGIVYEGLYKLNGKRVAIKHIDLLKNGSTSKSMELVSKEYNALKNIKHRNVIEFFDIVFSSTDCFFIVELATNDLSNLLRKRCVDEDDIKRICKQLLLGFNYLHNLGIVHRDLKPENILYNEFKQGFSIKITDFGLSSFVEESQYLQTFCGTPLFFAPEVIANNFFSNGYGKSCDLWSIGVTLYLSLCKYKPFIVDCRDLYHSFINGNLGFTSKKWAKISNYAKDLVRRLLVIDPEHRITIKEALNHPWFTQDRRFFKKYPKHYKSRAQPKTQFFVECFNVYYDLKSETGFICFREHFDNLETNYALFKQNFDNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNINNNNINNNNNNNNNNNNNTNTNNINNNNNNYNNSHNHNNNNHNHNHNLNNHNHNNNHHHNHNHNHNHNHNHNHNHNHNHNHNHNHNNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYYNNNINNINNNINNNINNNNNYHQQYTQHTTM
What are the official names of this protein?
Probable serine/threonine-protein kinase fhkB, Forkhead-associated kinase protein B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHK2 subfamily.
Protein: COAX_THEM4
Sequence: MKILFDVGNTHTTVALTENGKFFKIKRISTYSIQTEDELYAYLKVFFGETYDEVIVSSVVPNINHVFEFFSKKYAGKSAIFLNAQSYKGITWNVKIPSEIGADRVANIIAAERDYGKDAIVVDFGTAITIDILKEKSYEGGIIIPGFSMMINALFKGTAKLPKVELKPFNGFIGKDTESNIRIGIINTVVEGIGSVINKIKNENFRDVPVIFTGGQSKIIMDYKRDVIYDLELGLRGIYYFYESVVS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRS2I_ORYSI
Sequence: MAAAVVVAGEAAAAAGAGGKKRGASRSWILFDAAGEERVLDADKYAIMHRVDINARDLRILDPLLSYPSTILGRERAIVLNLEHIKAIITAEEVLLRDPLDDNVIPVVEELRRRLAPSSATQHDVEGAEEDESPFEFRALEVTLEAICSFLGARTTELESAAYPALDELTSKISSRNLDRVRKLKSGMTRLNARVQKVRDELEQLLDDDDDMADLYLSRKLAGAASPVSGSGGPNWFPASPTIGSKISRASRASAPTIHGNENDVEELEMLLEAYFMQIDGTLNKLTTLREYIDDTEDYINIQLDNHRNQLIQLELFLSSGTVCLSLYSLVAGIFGMNIPYTWNDNHGYVFKWVVLVSGLFCAFMFVSIVAYARHKGLVGS
What is the function of this protein?
Magnesium transporter that may mediate the influx of magnesium.
What are the official names of this protein?
Magnesium transporter MRS2-I.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS21_METI4
Sequence: MTEVKVKKGESIDKALRRLKRKLDREGTLREARLRKAFEKPCNRRRRKAKEARLKLYSSLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DLRB1_BOVIN
Sequence: MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
What are the official names of this protein?
Dynein light chain roadblock-type 1, Dynein light chain 2A, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the GAMAD family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FLOWR_DROSI
Sequence: MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRWLGIVAAFFAILFGLWNVFSIITLSVSCLVAGIIQMVAGFVVMLLEAPCCFVCFEQVNVIADKVDSKPLYFRAGLYIAMAIPPIILCFGLASLFGSGLIFGTGVVYGMMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV
What is the function of this protein?
A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis.  Required in the nervous system and necessary in photoreceptor cells (By similarity).
What are the official names of this protein?
Calcium channel flower.
What is the protein family that this protein belongs to?
Belongs to the calcium channel flower family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Upon fusion of the synaptic vesicle with the presynaptic membrane, protein is present in the periactive zones, where endocytosis is known to occur.
Protein: CPFC_LACCB
Sequence: MAKGLLIVNLGSPVSPETKDVRRYLREFLSDQNVITMPKALWQPILRGFILPFRSWRSATFYKHEWTQAGSPLIAYTQVTRDRLRERLPDWDVQMAMNYGGEYPIGETLQTMAARGDAPIVVIPLFPEYTQSTTKTILDKVAASGVKTVVIDRFYDHSDYQKILAQQIDDAYEAGAYDTVILSYHGIPTAMVRHGDPYQQECETTTAGVKQYLKKVPQTKVEMCYQSKFGPVPWLKPYLRNRLMELAALGKRNVLVATPSFVADCLETLEENNVQNYQTFRANGGKNFATVRPMNGCEPFCDFLAKLAKDKIAAEANHGKA
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PZ02_LUPPO
Sequence: MARPQQRYRGFRQRHWGSWVSEIRHSILKTRIWQGTFESAEDAARAYDEAARLMCGTRARTNFPYNPNASQSSSSKLLSATLIAKLHRCYMASLQMTRPSSLPEAPRIIASPNNAVKGIGADAMLLPKKREQEEQETGGNLDFKKVKVECSQQFKPLEEDHIAQ
What is the function of this protein?
Essential for all lupin cells independent of the respective tissue.
What are the official names of this protein?
Protein PPLZ02.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_MYCSJ
Sequence: MPKAKTHSGASKRFRRTGTGKIVRQKANRRHLMEHKPTKRTRRLAGRTQVSANDAPRINKMLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TACY_LISIV
Sequence: MKKIMLLLMTLLLVSLPLAQEAQADASVYSYQGIISHMAPPASPPAKPKTPVEKKNAAQIDQYIQGLDYDKNNILVYDGEAVKNVPPKAGYKEGNQYIVVEKKKKSINQNNADIQVINSLASLTYPGALVKANSELVENQPDVLPVKRDSVTLSIDLPGMVNHDNEIVVQNATKSNINDGVNTLVDRWNNKYSEEYPNISAKIDYDQEMAYSESQLVAKFGAAFKAVNNSLNVNFGAISEGKVQEEVINFKQIYYTVNVNEPTSPSRFFGKSVTKENLQALGVNAENPPAYISSVAYGRDIFVKLSTSSHSTRVKAAFDTAFKGKSVKGDTELENIIQNASFKAVIYGGSAKDEVEIIDGDLSKLRDILKQGANFDKKNPGVPIAYTTNFLKDNQLAVVKNNSEYIETTSKAYSDGKINLDHSGAYVARFNVTWDEVSYDANGNEVVEHKKWSENDKDKLAHFTTSIYLPGNARNINIHAKECTGLAWEWWRTVVDDRNLPLVKNRNVCIWGTTLYPAYSDTVDNPIK
What is the function of this protein?
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes.  After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus.  Can be reversibly inactivated by oxidation.
What are the official names of this protein?
Ivanolysin, Thiol-activated cytolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host membrane; Multi-pass membrane protein. Note=Secreted as soluble protein that then inserts into the host membrane and forms pores formed by transmembrane beta-strands.
Protein: PATR_NOCFA
Sequence: MSARIRPDLSSIPAYTPGRSNPGAVKLASNETTLPPLPAAAKAIAEAAELAHRYPDNQSGELRAALAEFLGVRVENVAIGCGSVALCQELVQITCSSPRDEVLFAWRSFEAYPIITQVGNATAVQVPLSPDYAHDLDALAAAVTEHTRLIFVCNPNNPTGTAHGRAALERFLDAVPAHVLVVLDEAYYEYMRLTPQDRPDGVEVGRNRPNVVVLRTFSKAYGLAGLRVGYAVGDPEVITALMKVHIPFSVNRVAQAAAIASLEARHELLERTEAVIVERERLREALLAAGYDVPPSETNFVWLPLGAHSAEFGEASAAAGVLVRPYGTDGVRVTVGDPHENEMFLRFAADPAVVARFR
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: RECX_LACJO
Sequence: MPIITKISTQKRKGRYNIFIDNEYAFSVSERTLAEKRLLKGTELSLEDIEKIKKAEADSHALQLAMSYLSYQPRSVYEVLTYLNKQGISPEASQSAIENLIELNYLDDNNFARLFIQNNLRVGKDGPRSISSKLKQKGVANDIIQDSLYEVDDEEWIEAGMRLIHSIGHQVGKMSYKEIKQKALKKLQTHGFNQELGELVVDQLDLESTEDDQLEALKKQGIKAWRRYRRDDDFKRRQKVKRYLFQHGFSSGEIDSFLSGEVVNLEEIDEY
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP3_BOTJA
Sequence: MVLIRVIANLLILQLSNAQKSSELVIGGDECNITEHRFLVEIFNSSGLFCGGTLIDQEWVLSAAHCDMRNMRIYLGVHNEGVQHADQQRRFAREKFFCLSSRNYTKWDKDIMLIRLNRPVNNSEHIAPLSLPSNPPSVGSVCRIMGWGTITSPNATFPDVPHCANINLFNYTVCRGAHAGLPATSRTLCAGVLQGGIDTCGGDSGGPLICNGTFQGIVSWGGHPCAQPGEPALYTKVFDYLPWIQSIIAGNTTATCPP
What is the function of this protein?
Snake venom serine protease that has a potent and selective fibrinogenolytic activity.  Preferentially cleaves the alpha-chain (FGA) of human and rat fibrinogen at Arg-|-Gly bonds, and slowly digests the beta-chain (FGB) (PubMed:18433459).  In vivo, completely avoids thrombus formation induced in rat, decreases the fibrinogen plasma level and prolonges the recalcification time.  Possesses esterolytic and amidolytic activities.
What are the official names of this protein?
Snake venom serine protease BPA, SVSP, Bothrops protease A, BPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_PHOLL
Sequence: MIPLQHGLILAAILFVLGLTGLIIRRNLLFMLIGLEVMINAAALAFVVVGSYWGQPDGQVMFILAISLAAAEASIGLALLLQLYRRRQNLNIDTVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPV1_PSEAE
Sequence: MSEISRVALFGKLNSLAYKAIEAATVFCKLRGNPYVELVHWFHQILQLPDSDLHQIVRQSGIDPARLAKDLTEALDRLPRGSTSITDLSSHVEEAVERGWVYGSLMFGESQVRTGYLVIGILKTPSLRHALTGLSAEFAKLKVEALTERFDEYVGASPENGLSASDGFNAGAAPGEASGALAPSAMGKQEALKRFTVDLTEQARSGKLDPIVGRDEEIRQLVDILMRRRQNNPILTGEAGVGKTAVVEGFALRIVAGDVPPALKDVELRALDVGLLQAGASMKGEFEQRLRQVIEDVQSSEKPIILFIDEAHTLVGAGGAAGTGDAANLLKPALARGTLRTVAATTWAEYKKHIEKDPALTRRFQVVQVDEPSEHKAILMMRGVASTMEKHHQVQILDEALEAAVRLSHRYIPARQLPDKSVSLLDTACARTAISLHAVPAEVDDSRRRIEALETELAIIRRESAIGVATAERQRNAETLLAEERERLAALEQRWAEEKRLVDELLETRARLRAAAEAVDAGGVPLGEGEVRLDEEQRQALHARLAELQAQLSALQGEEPLILPTVDYQAVASVVADWTGIPVGRMARNEIETVLNLDRHLKKRIIGQDHALEMIAKRIQTSRAGLDNPSKPIGVFMLAGTSGVGKTETALALAEAMYGGEQNVITINMSEFQEAHTVSTLKGAPPGYIGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVHEIFFQVFDKGVMEDGEGRVIDFKNTLILLTTNAGTEMIASLCADPELMPEPEAIAKSLREPLLKIFPPALLGRLVTIPYYPLSDDMLKAISRLQLGRIKKRVEATHKVPFEFDEGVVDLIVSRCTETESGGRMIDAILTNTLLPDMSREFLTRMLEGKPLAGVRISSRDNQFHYDFAEAE
What is the function of this protein?
Component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species.  Acts as an AAA(+) ATPase that disassembles the contracted sheath, which resets the systems for reassembly of an extended sheath that is ready to fire again.
What are the official names of this protein?
AAA+ ATPase ClpV1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BACSU
Sequence: MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFEVDEGLRTLMDFRYKKHFKAIRGEHGMSKNQHGRNADDMVIKVPPGTVVTDDDTKQVIADLTEHGQRAVIARGGRGGRGNSRFATPANPAPQLSENGEPGKERYIVLELKVLADVGLVGFPSVGKSTLLSVVSSAKPKIADYHFTTLVPNLGMVETDDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVIVHVIDMSGLEGRDPYDDYLTINQELSEYNLRLTERPQIIVANKMDMPEAAENLEAFKEKLTDDYPVFPISAVTREGLRELLFEVANQLENTPEFPLYDEEELTQNRVMYTMENEEVPFNITRDPDGVFVLSGDSLERLFKMTDFSRDESVKRFARQMRGMGVDEALRERGAKDGDIIRLLEFEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg, OrfA, Spo0B-associated GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Cofractionates with the ribosome and stress response regulators RsbR, RsbS and RsbT in size fractionation columns; binds to ribosomal protein L13.
Protein: MK09_HUMAN
Sequence: MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPLEGCR
What is the function of this protein?
MAPK9 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to JUN, whereas beta-1 and beta-2 bind to ATF2.  However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.  JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
What are the official names of this protein?
Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, JNK-55, Stress-activated protein kinase 1a, SAPK1a, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with POU5F1 in the nucleus.
Protein: REC27_SCHPO
Sequence: MKKRSETLGSDQSSSEIIEHVLEELNLKNIERRVKKYDQIESEYKTNIENEKKAFIKDVSQVQQKIKEFEIQKANQIKQLNEEKLSIEARKQQLEIEIRNQLLQYAEKLRIVVKTPMNQPTNTEV
What is the function of this protein?
During meiotic DNA recombination, binds to and activates DNA double-strand break (DSB) hotspot sites.
What are the official names of this protein?
Linear element protein rec27, Meiotic recombination protein rec27, Meiotically up-regulated gene 41 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=Localizes to chromosomal double-strand break (DSB) hotspot sites during the meiotic cell cycle.
Protein: HORM2_MOUSE
Sequence: MATAQLSHNTRTLKASKNTIFPSQVTNEHESLVVVKKLFATCISCITYLRGLFPESSYRDRRLDDLSLKILREDKKCPGSLHIIKWIQGCFDALEKRYLHMAVLTLYTNPKEPEKVTEIYQFRFKYTKKGTTMDFDSSSTSFESGTDSEDIKKACSLLIRQLYILMQNLGPLPNDVILTMKLHYYNSVTPHDYQPPGFKEAVNSHFLLFEGEPVSLRMGSVSSGFHSMKVKVTTEATRMLDGENSVSQDDGTTEIAHQGLDCDEEEEACGSQVQRMNFVHIEPSFESSRKKKKVSEPVTVFIPNRK
What is the function of this protein?
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.  Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.
What are the official names of this protein?
HORMA domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes.
Protein: ACCA_STRMK
Sequence: MNPNYLDFEQPIADLEAKIQELRNASAGPAVNVEAEVHALQDKLRMRTAQIFRNLTSWQVLQLARHPSRPYTADYLRVMFDEFQELAGDRAFADDKAIMGGLARINGRAVMVIGHQKGRDTKEKIKRNFGMPKPEGYRKALRLMKMAERFGLPVLTLIDTAGAWPGIDAESRGQSEAIARNLIEMAELKVPIICTVIGEGGSGGALALGVGDRTVMLEYAVYSTITPEGCASILWKDAGKAKDAAEQLGLTAPRLKSLGLVDKVVREPTGGAHRNPTQMAKRLKAVLLNELDALDKLSTEQLLEQRYARLRSYGTYEAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAT_BUCAI
Sequence: MKILISDNISLELFCKNPIKILEKSNKGIIGVLKNKSPIFYVITPYILKKIFDLECNLLDLDKTKQQISKKFSMHPQWTPDKDFIRQAALWGITLTEEILESELASFISYWQAEGCFFHHIQWQQKLARSLQKSRSISYMSQKKRDITYIPTPDQTVPNGFRGK
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity).
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: SLSG4_BRAOL
Sequence: VRKNYNNCYILSFLLVFFVLILFPPAFTINTLSSIESLTISSNRTLVSPGNVFELGFFRTNSSSRWYLGIWYKKVSDRTYVWVANRDNPLSSSIGTLKISGNNPCHLDHSNKSVWSTNLTRGNERSPVVADVLANGNFVMRDSNNNDASGFLWQSFDFPTDTLLPEMKLSYDLKTGLNRFLTSRRSSDDPSSGDFSYKLEPRRLPEFYLSSGVFLLYRSGPWNGIRFSGLPDDQKLSYLVYISQDMRVAYKFRMTNNSFYSRLFVSFSGYIEQQTWNPSSQMWNSFWAFPLDSQCYTYRACGPYSYCVVNTSAICNCIQGFNPSNVQQWDQRVWAGGCIRRTRLSGSGDGFTRMKNMKLPETTMAIVDRSIGVKECEKRCLNDCNCTAFANADIRNGGTGCVINTGELEDMRSYATGATDSQDLYVRLAAADIV
What is the function of this protein?
Involved in sporophytic self-incompatibility system (the inability of flowering plants to achieve self-fertilization).
What are the official names of this protein?
S-locus-specific glycoprotein S14, SLSG-14.
Protein: MED8_SCHPO
Sequence: MEDISTEKTVESLEAIRHRIAQIVQSLTHFLAILHQSESLSPWPTIHKNFNILLSQIHSLSNNLAAHSHTLQTTSIYPSLEFPVKEQEPLLTTLLRTKALPEVEEWEANTLQEYEASISSQPKKKEANDAYQKDQLWDQARIIFMEERENYSWFDFVTRRQESEGEFVSQRQLEIDRATEEQNANQMLTDILSFMKSGKR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Cell separation protein sep15, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.