PharMolix/UniProtQA huggingface dataset:
Protein: PPK1_DICDI
Sequence: MITNSKMENKILDEFDEEELNKLKINSNNKESTTTTTSTTTTTTTTTSTSGEESDDEHTGSSSSTAAMELHRYKISQECPVDFEDDYDEESSSFDEEDEDSAAESNGGNGKLIPNPNDKKKKRSSKSSSKSSKSKSKSKNKETTANPVQNCQLMESGTLFSPTEFVKSSTVNPSKSPVQPIKLSSMLGLSELGTSNVLTVQNPQPISEPLKNDISSGSSSSSSSNNNNSNSNSNGNCNSDSTKSKFTSLNSWDAPPLANVLPDPSYCQDIVDSENNFIVPSVKHTILDVDNLFNNLIQNTNNNNNNDFKSSTMIGKPFSSGGDGSTSPLISGLSSSSIIPNGNGSLAEQQQQQQQSIPESEIPIDIKVLQLSGSRMFFNRELSELIYFYRILYEAYNPTYPILERVRFIAITSQNLDMYFCKRALKLRLGYISTRKTLKPEEHYINMVLNTTRNLINEIYNIYMNILAPELSNNNVFIIKYSDLTEPEKIQLRGFFLQHVFPLMTPLVVDAGHPFPNLSNLSLNIAVLLKHDEDTTRFVRIKVPQRIPRFVHIKQRSNYSIIPMEEIILANLDTLFPNTKILTKSLFRVSRHNDLKLSGEDQANDLLELIKTELHKRKFAPMVRLEVSHNMPAEILDMLKTQLALDAYDVYVINGPLGLQDLFELCKLNLPHLKFQPWVPHIPSRLVNLAKYPSEDVFSVIRKGELLVNLPYLSFNSSVQFFIESAVKDPKVLAIKIAIYRTNSNSQLIRALCEAASHKEVMVLVDLKASGDEEQNTKFARLLEQAGCHVSYGLVGLKTHAKIAMVVREEENGLREYLNISTGNYNASTSDVYADICLFSCDPDLGEDMCNLFNYLTGYSRVSSFKKLLIAPMNMRSTLIQLIDNEAKNAREGKDATINAVMNGLDDKRLVNALYQASIAGVKITLVVRGRCRILPGIKGISENIKVISILGRFLEHSRIYCFHNNGKPKAYIASADWLHRNLKRRVEVMVPVDDANNIKQLYEIINVYCNDSNAWEMLSDGRYKKRSSPIDEDSQTQFMNQTNQKHPVIWSK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).  Produces polyP in a broad range of chain lengths (50-300 Pi residues).  Involved in development (growth and fruiting body formation), sporulation, phagocytosis, cell division and the late stages of cytokinesis.
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphate kinase 1, PPK1, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
What are the subcellular locations of this protein?
Vesicle.
Protein: NHAA_PSEE4
Sequence: MNAPLHPLKQPSMLRQLLATEAAGGVLLMFTAALAIIIANSPWASAYQHLLHLPVGPVLTDKLGPMTVHMWINDGLMAIFFLLVGLEIKRELVDGRLASWEQRRLPALPALMGMAVPALIYLAVSRGELGLAGGWAIPAATDIAFAVGALALLGKHAPLSLKVMLVSVAIIDDMGAVAIIAVFYTSSINLLALAGAAGIVAVLLAFNRLRVVALWPYLIGVAALWYVTLLSGVHATIAGVVGALLIPYSAGSGAEREASPLLKLEHGLAPWVGFLIVPAFGFANAGVSFGDLGWSDIFAPLPLAIALGLLLGKQLGVFAGVLLAVKSGLASKPRGASWLQIYGVAMLCGIGFTMSLFIGELAFPGQPEKIDAAKIGILLGSLLSAVIACVILRFAPKQAD
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGBB_HELPY
Sequence: MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKGVEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASVKGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSDKFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPSSLNTIVLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKSASKKSQKGEKGNAPIYLQERHKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKENAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK
What is the function of this protein?
Binds plasminogen, specifically, and in a concentration and lysine-dependent manner.  Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin.  Acquisition of plasminogen/plasmin could enable H. pylori to degrade host components.
What are the official names of this protein?
Plasminogen-binding protein PgbB.
What are the subcellular locations of this protein?
Cell surface. Note=The plasminogen- binding region is localized on the surface the bacterium.
Protein: DHOM_BACSU
Sequence: MKAIRVGLLGLGTVGSGVVKIIQDHQDKLMHQVGCPVTIKKVLVKDLEKKREVDLPKEVLTTEVYDVIDDPDVDVVIEVIGGVEQTKQYLVDALRSKKHVVTANKDLMAVYGSELLAEAKENGCDIYFEASVAGGIPILRTLEEGLSSDRITKMMGIVNGTTNFILTKMIKEKSPYEEVLKEAQDLGFAEADPTSDVEGLDAARKMAILARLGFSMNVDLEDVKVKGISQITDEDISFSKRLGYTMKLIGIAQRDGSKIEVSVQPTLLPDHHPLSAVHNEFNAVYVYGEAVGETMFYGPGAGSMPTATSVVSDLVAVMKNMRLGVTGNSFVGPQYEKNMKSPSDIYAQQFLRIHVKDEVGSFSKITSVFSERGVSFEKILQLPIKGHDELAEIVIVTHHTSEADFSDILQNLNDLEVVQEVKSTYRVEGNGWS
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: CMOA_ALTMD
Sequence: MKKHDNIYAKALNKVDDFKFDESVVDVFPDMIQRSVPGYETIVHTIGELAKSSVTPNSMVYDLGCSLGAASLSVSRAVSANTCEIIGVDASSAMVERCRRVVQTFTLPNPISIEQGLAQDVDINNASMVVMNFTLQFIPPSDREGLLASIYKGLNPGGILVLSEKVKHPTRSGNELLIDLHHQFKRDNGYSELEVSQKRAALEKVMLTDTFNEHETRLKKVGFADVVMWYKCYNFTSMVAIKA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CLSA_ENT38
Sequence: MTTFYTVVSWLVILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERARAMWPSTAKWLNDLKSCKHIFAEENSSVASSLFKLCERRQGIAGVKGNQLQLLTTSEDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAASRRGIHCRLMLDSAGSVAFFRSPWAGMMRNAGIEVVEALKVNLLRVFLRRMDLRQHRKMIMIDNYIAYTGSMNMVDPRFFKQDSGVGQWIDLMARMEGPVATAMGIVYSCDWEIETGKRILPPPPDANIMPFEQESGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIMPRKNDSVLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDAGFGGDLAAVQDDYISRSRLLDASLWVKRPLWQRITERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IIGP5_BOVIN
Sequence: MATSKLPAVSGEEETTILMAKEELEALRTAFESGDIPQAASRLRELLASSDCTRLEVGVTGESGAGKSSLINALRGLGAEDPDAALTGVVETTIEPSPYPHPQFPDVTLWDLPGAGSPGCSADKYLKQVDFGRYDFFLLVSPRRCGAVETRLASEILRQGKKFYFVRTKVDEDLAATRMQRPSGFSEGAVLHEIREHCVERLRGAGVHDPRVFLVSNLSPARYDFPLLMSTWERDLPAHRRHAGLLSLPDISLEALQEKKDMLQEQVLKTALVSGVIQALPVPGLAAAYDDALLIRSLRGYHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARAFEKGIPVFGTLVAGGISFGTVYTMLQGCLNEMAEDAQRVRIKALEEEEDTQPDVSLEAAGDNGVEKRGSGEGSMEEAPLSTRRKLGLLLKYILDSWKKRDLAEDK
What are the official names of this protein?
Interferon-inducible GTPase 5, Immunity-related GTPase cinema 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.
Protein: DTPA_SALTI
Sequence: MSTANKKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKILGTKRVIMLGAVVLAIGYALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYAKDDPRLDGAFTMYYMSVNIGSFFSMLATPWLAARYGWSTAFALSVVGMLITVVNFAFCQRWVKSYGSKPDFEPINFRNLLLTIVGIVVLIAVATWLLHNQDIARMVLGVIALGIVIIFGKEAFSMHGAARRKMIVAFILMLQAIIFFVLYSQMPTSLNFFAIRNVEHSILGIAFEPEQYQALNPFWIITGSPILAAIYNRMGDTLPMPMKFAIGMVLCSGAFLILPLGAKFANDAGIVSVNWLIASYGLQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANIIGGYVANLMAVPSDVTDPLMSLEVYGRVFMQIGIATAVIAVLMLLTAPKLNRMTQDDDTAEKGSKAATV
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPX1_CALJA
Sequence: MCAAGLAAAAAQSVYAFSARQLAGGEPVSLGSLRCKGLLIENVASLUGTTVRDYTQMNEPQRRLGPRGLVVLGFPCNHSGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKGEVNGAGAHTLFAFLREALPAPSDDATALMIDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
What is the function of this protein?
Protects the hemoglobin in erythrocytes from oxidative breakdown.  In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
What are the official names of this protein?
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_RHIME
Sequence: MPLRMIFMGTPEFSVPTLLALAGAGHEIAAVYTQPPRPGGRRGLDLQKSPVHQAAERLGIPVLTPANFKDAADRQTFRDFGADVAVVVAYGLLLPEEILSGTRYGCYNGHASLLPRWRGAAPIQRAIMAGDRETGMMVMKMDKGLDTGPVALAQSVPIDGMMRAGELHDRLMQVGAVLMTEAMARLESGELPLAPQAQEGVAYAAKISKEETRIDFSRPAAEVHNHIRGLSPFPGAWFELDIAGRRERVKVLASEMSEGEGDPGEVLDHTLGIACGEGAVRLTRLQRAGGKALAAADFLRGTPIAAGARIA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DAPA_CAUVC
Sequence: MVQSHFKGVIPALVTPFRDGEVDEKAFVALVERQIAGGVHGLVPVGTTGETSTLSHEEHRRVVELCVKTTAGRVPVIAGAGSNSTDEAIELARHAKTVGADACLVVTPYYNRPSQEGMYQHYKAINDAVELPIFVYNVPGRTGVDISNDTLERLAKLPNIVGIKDATGDLTRISFQRLMCGPEWVMLSGDDPTALGYMAHGGHGVISVTSNVAPDACSAFMNACMQGEWEKGLYWQDRLVRLHKALFLDSSPAPTKFAMAQLGLCTEDVRLPITACAEGVRPAILEAMREAGLR
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKO1_CANAL
Sequence: MSSDHKSKFDLELNPFERSFATKESSSVSLNELAAASNNDAISDVNSVATSGSSINNGSSSNKHNLHIPNISSVNQQQGVNGKLPGITPPLFTPGGRRLPPIGLSPGGTTSRQYSNSTNSGSLQSNTDTLGSNIWGGLPTNQTFQPQPQPQPQPQQQQQPQQQQQTQQPHNFNQFMSGMRKTGLTPNESNIRSGLTPGGLTNFGFGSNLVPGLSTPGALLNGPITPGLSSLLGITQTPSSLLVPTTSSFSQNNQSHLIQPAANTSVGPIPESTALGPHVNIPQANQLQQDQSSQALVGGLPPSQPQPQPQPVIAQQIHTIPENQSIAFDMTQPAVANAHLPESKPDLSETANLQRDLNPTADTTTNTTTATKKRKNDTAGGTNKKAKVAKGKKKEPKSKSKGKNNQEDDQNASNKPEDENVPGKENGNEENHKVEAESKEEHLQNGNETTTTKTNNTGNSSNGTTTTTTTKSKSKKNSNVSEDDKRKNFLERNRVAASKCRQRKKLLIQKMEEELEFYSNGYRELSAEVNELRGAILLLKEKHNIQDEIIDGLLSKPTTVPTNVTSIPSTIPTTLNPT
What is the function of this protein?
Transcription repressor involved in cell wall damage response.  Regulates 79 caspofungin-responsive genes, including several cell wall biogenesis genes such as CRH11, MNN2, and SKN1.  Controls also the expression of pathogenesis and hyphal related genes and represses the yeast-to-hypha transition.  Mediates the response to oxidative stress.
What are the official names of this protein?
Transcriptional regulator SKO1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_MYCPN
Sequence: MKKINKQALIDLVEQKQLKAYVPEFSAGDEVNVAIKLKEKEKVRIQNFTGTVLRRRGKGISETFIVRKTTDGIPIEKNFQIHNPNISIELKRRGKVRRAYISYMRERSGKAAKIKERKQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NCDN_HUMAN
Sequence: MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP
What is the function of this protein?
Probably involved in signal transduction in the nervous system, via increasing cell surface localization of GRM5/mGluR5 and positively regulating its signaling (PubMed:33711248).  Required for the spatial learning process.  Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation.  May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction.  May be involved in bone metabolism.  May also be involved in neurite outgrowth (Probable).
What are the official names of this protein?
Neurochondrin.
What is the protein family that this protein belongs to?
Belongs to the neurochondrin family.
Protein: FABZ_STAAC
Sequence: METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ESCF3
Sequence: MKILVDENMPYARELFSRLGEVKAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGLLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_BORHD
Sequence: MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIASLGWSKIFVDRYDGIILDYALKNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLPSSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKFIDKLS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEMS_PRAMA
Sequence: QDVDHVFLRF
What is the function of this protein?
Myoinhibiting neuropeptide.
What are the official names of this protein?
Myosuppressin, MS.
What is the protein family that this protein belongs to?
Belongs to the myosuppressin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CT34_CONBE
Sequence: MRGLPVFVILLLLIASEPSVDARPKTKADVPLTSLNDNAKRTLQILRNKRACCPYEPSCCI
What are the official names of this protein?
Conotoxin Bt5.1, Conotoxin BeB34.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_DACMI
Sequence: MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMVPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EPHB3_MOUSE
Sequence: MAGARPPPGLLPLLAPLLLPLLLPAGCWALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRREVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIANAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRACPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLHLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSKGIASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQYSHPAEFETTSERGSGAQQLQEQLPLIVGSTVAGFVFMVVVVVIALVCLRKQRHGPDAEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKLPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILCSIQDMRLQMNQTLPVQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Generally has an overlapping and redundant function with EPHB2.  Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses.  Controls other aspects of development through regulation of cell migration and positioning.  This includes angiogenesis, palate development and thymic epithelium development for instance.  Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca.  Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.
What are the official names of this protein?
Ephrin type-B receptor 3, Developmental kinase 5, mDK-5, Tyrosine-protein kinase receptor SEK-4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: BUK_LISMO
Sequence: MSFDVLTINPGSTSTKLAVYQGDKVLFEETVRHTMQELADFNNVQEQFDFRWQVLRRVMDAHGYDVKKLQAVVGRGGLLRPVAGGTYMVTEKMIDDLKENKYGEHASNLGAMLAKKLADELTIPSFIVDPVVVDEMQEIARISGNAFVTRKSIFHALNHKAAGRKIAKELGKDYEKMNFVIAHLGGGISVAAHRQGKAVDVNNALDGDGPFSPERSGSLPMNDFLEACFSGKWTKRELHELIVGRGGMISYLGTNSMLEVEAKVQAGEEKAIEAFDAMAYQVSKEIGACSVVLQGKVDAIILTGGLARSELFTSKIIEQTNWITSVIIEPGEDELEALNSGVQRVLAGLEKEKEY
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTX1_CAEEL
Sequence: MELHIWPSDFGLPTIDVVSLQFLACSKMCASPVRVIQSTRPWRSPSGELPMVAQTEGEAKPVTDFEKFVDILKKCGQDVVIDADLTTIEKAQLDAFSCYLHHNLYPAVMHTFWTDELNYNTVTQYWYASHLHFPYNLYYLEKRRKKALRLLAGKNDTEILKEAFMALNTLSTKLGDNKFFCGNKPTSLDALVFGYLAPLLRVPLPNDRLQVQLSACPNLVRFVETVSSIYLPLGEDELKRQQANRKMWQSRISKAKADKEAAKTTEEASESLPEEPPMRDAILFTLGALTLSLVFAIHTGLIQVSVEEEISE
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.  Essential for embryonic development (By similarity).
What are the official names of this protein?
Metaxin-1 homolog, Mitochondrial outer membrane import complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: ID3_MOUSE
Sequence: MKALSPVRGCYEAVCCLSERSLAIARGRGKSPSTEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELTPELVISKDKRSFCH
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.  Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation.  Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer.  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer.
What are the official names of this protein?
DNA-binding protein inhibitor ID-3, ID-like protein inhibitor HLH 462, Inhibitor of DNA binding 3, Inhibitor of differentiation 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear in proliferating cells, translocates to cytosol during cell differentiation.