PharMolix/UniProtQA huggingface dataset:
Protein: ENO_CHLL2
Sequence: MPIIRKVLARQILDSRGNPTVEVDVYTENSFGRAAVPSGASTGIHEAVELRDGDAGIYLGKGVLKAVDNVNTVINDALKGMLVTEQEEIDEALLALDGTPNKSKLGANALLGVSLACAKAGAEYTGLPLFRYIGGTMANTLPVPMMNVLNGGAHADNTVDFQEFMIMPIGFSSYSDALRCGAEIFHALKSLLKSKGLSTAVGDEGGFAPNLRSNEEAIELVIEAIGKAGYKAGSPTDKGGLGEAQVMIALDPASSEFYDSAKKRYVFKKSSKQELTSLEMAEYWEKWASDYPIISIEDGMAEDDWEGWKILTDKIGSRVQLVGDDLFVTNSKRLAEGIERRVGNSILIKVNQIGTLTETLQAIDLAKRNGYTAVISHRSGETEDSTIAQIAVATNAGQIKTGSMSRSDRMAKYNELLRIEEELCGQAKYPGASAFRV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TFEC_PANTR
Sequence: MTLDHQIINPTLKWSQPAVPSGGPLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEGADSPLLMQRTLSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVDYCQQLTVSQRPSPEFCDQAIAFSDPLSYFTDLSFSAALKEEQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL
What is the function of this protein?
Transcriptional regulator that acts as a repressor or an activator.  Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence).  Binds to element F in an E-box sequence-specific manner.  Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter.  Collaborates with MITF in target gene activation.  Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence.  Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer.  Binds DNA in a homo- or heterodimeric form (By similarity).
What are the official names of this protein?
Transcription factor EC, TFE-C.
What is the protein family that this protein belongs to?
Belongs to the MiT/TFE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLB_PROJR
Sequence: MGRFIFVSFGLLVVFLSLSGTGADCPSDWSSYEGHCYRVFQQQMNWADAEKFCTQQRKESHLVSFESSEEVDFVVSKTFPILKENFVWIGLSNVWNGCRLQWSDGTELKYNAWSAESECIASKTTDNQWWSMDCSKTYPFVCKLIV
What is the function of this protein?
Snaclec that dose-dependently inhibits platelet aggregation induced by ristocetin or low-dose thrombin, but not by high-dose thrombin.  Binds to GPIbalpha (GP1BA).  In vivo, also dose-dependently induces thrombocytopenia of mice and platelet counts remains at very low level even after 18 hours intravenous injection.
What are the official names of this protein?
Snaclec jerdonibitin subunit beta, TJ-GPIb-bp subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGZ_SALG2
Sequence: MGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKTTGKHFPGHGAVTADSHKETPCDPRPETDIRGKDMSVFRTLISENKLDAIMPAHVIYRAIDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRRELMDSARWKTASAQLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_XANP2
Sequence: MKSDIHPDYHFIKVVMTDGSEYTTRSTYGKEGDTLQLDIDPRTHPAWTGGTQQLMDRGGRVSRFKSKFGALLKG
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PTG3C_STAA2
Sequence: MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAIQGEALQHYLPFIQNGGVQNVAKLMTAAGSIIFENLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNVTDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDVHLGYTFSGGFIDYVLLGVLPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAVTASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKIQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICBA component, EIICBA-Glc, EII-Glc, EIICBA-Glc 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRED_HAEIN
Sequence: MQTRFILQWFTILSFFVIAFVLELAPWPVGFQMLKPAWLVLVLLYWVLAIPNKVSIGWSFLLGLTWDLILGSTLGVHALVLSTSMYIIAKNYLILRNLSLWFQSLLVVLFVFIIRLLIFLVEFSLHTAFFHWQAILGAFASGLLWPWVFLLMRKIRRKVKLH
What is the function of this protein?
Involved in formation of the rod shape of the cell.  May also contribute to regulation of formation of penicillin-binding proteins (By similarity).
What are the official names of this protein?
Rod shape-determining protein MreD.
What is the protein family that this protein belongs to?
Belongs to the MreD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_ANADF
Sequence: MVKDRVIELFRQALAKGAAEGRWPALEASFSVEAPRDPKHGDFAVNAAMVLAKAAGKPPRDLAQAIAAEVRAVDAQHEIAGLEVAGPGFINVRLAPDVWLRALGRVVAEGTAYGRTEVGRGKKVIVEYVSANPTGPMHVGHGRNAVVGDGVQSLLRWAGFEVTREYYVNDYGAQVQTLARSVHLRYQELFGRQVTMPPKSYPGEYVKDVAAALKAEHGDRWLDAPEAEWLALFRDRAVEHVLGLIREDLRAVNIEFDRWYSEKALYESGTVDRFLRFLAEKDLVYVGKLPPPKSKKGQPAPAQAASNSAHDLGEEGIAASDDLTLFRSSQYGDEVDRPVKKADGTTTYFCADIAYHWDKRQRADALVDVLGADHGGYVPRLEAALEALGASRKDLHVVLIQMVNLTRGGEAVKMSKRAGTVVSLREVVDEVGRDATRFIFLTRRSDAQLDFDIELAKRQTLDNPVFYVQYGHARLAQIFAKAREAGAPVPEFDLEAARTLTSAEEQDLIRRIVAFPDMLAAAALAYEPHRVAFYLQETIAAFHSYYTQGKRTGERVISADARKTAGRLFLCRALKQVLANGLGLLGVAAPERMESPETRDLADDV
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_LIMF3
Sequence: MKQLINNDWWPVLKPQFETANYQQLHNFLVDEYGHQQVYPEMHHIFEAFNWTPFSKVKVVILGQDPYHGPGQAHGCSFSVLPGVAVPPSLQNIYKELQADLGCPPVKHGYLRSWAEQGVLLLNSVLTVRAGQAYSHQGHGWEQLTDAAIVALSKRPTPVVFILWGRAARDKKRLIDLKRNFVVESAHPSPLSAYRGFFGSRPFSKTNQFLEMTGQAPINWQLPSTVDHL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_PASMU
Sequence: MSVIPMVVEQTARGERSYDIYSRLLKERVIFLGGEVEDRMANLIVAQLLFLESEDPEKDINIYINSPGGSVTAGMAIYDTMQFVKPDIRTLCVGQACSMGAFLLAGGTAGKRIALPSARVMIHQPLGGFRGQASDIQIHAQEILKIKQTLNERLAFHTGQTIERIERDTDRDNFMSAEEAKAYGLVDEVLASR
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKG2D_PONPY
Sequence: MGWIRGRRSRHSWEMSEFHNYNLDLAKNDFSTRWQKQRCPVIKSKCRENTSPLFFCCFIAVAMGIRFIVMVTIWSAVFLNSLFNQEVQIPLTGSYCGPCPKNWICYKNNCYQFFNESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLIHIPTNGSWQWEDGSILSPNLLTIIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
What is the function of this protein?
Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells.  Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity.  Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation.  Stimulates perforin-mediated elimination of ligand-expressing tumor cells.  Signaling involves calcium influx, culminating in the expression of TNF-alpha.  Participates in NK cell-mediated bone marrow graft rejection.  May play a regulatory role in differentiation and survival of NK cells.  Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins (By similarity).
What are the official names of this protein?
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Colocalized with HCST on the cell surface.
Protein: TUSA_ECO81
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_RHOPS
Sequence: MGDLIFPINPGAALAIHVALSAGIVAAIIVVAAWLREKRSGARADVPYEGGVLPAAPQQGPVNAPYFLIAALFVIFDMEAAILFAWAVAARDTGWLGLIEAAVFIGVLLLALVYLWADGALDWHKERRR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURE_PROMH
Sequence: MLKILVSNDDGVMAKGIQTLAKALRQRYDVQIVAPDRNRSAASNSLTIDRPLRKQRHENGDIAIVEGTPTDCVYLGVNHLVRPRPDIVVSGINHGPNLGDDVLYSGTVAAATEGRFLGLPAIAVSLDGETHFDTAAQVTCDVLAMLQRVPLRAGNILNINVPDIPLAEIKGFRITRCGSRHASQHVYTQTDPKGNTLYWIGPPGEKNDVGPDTDFAAVDAGYVSITPLHVDSTAYKALELLKDWLNKAEVEKTC
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_SERP5
Sequence: MTDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEERVKTNYDHPSAMDHNLLFQHLQMLKSGKAIELPLYSYTEHTRKKETIHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIDPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_STAAR
Sequence: MISIILVMIGGGLGAIARSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLAKELTLMMTPKFNINLFLNYSLLQFIIGFIACYIGYHI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HMUV_BARQU
Sequence: MIEAVNICVQRGKKQILNHIDFQAKSSALTVIIGPNGSGKSTFVKALSGEIPYSGKMTLNGHDVTHTKTYEMAAMRAVLPQFTTLAFPFLVHEVVALGLSVNQFTIAKKQLQNLPQKALECVGLADYGNRHYHQLSGGEQARVQLARVLCQIWEPVCNKVPRWMILDEPIANLDIQHQLVVMNIARNFARCGGGVLAVLHDLNLAAHYADKMILLKQGKIYCEGSASTVLTTQNLSDAYHCSLPVSELPKADTPFVLPQTASFL
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GATA9_ARATH
Sequence: MEKIAPELFLVAGNPDSFVVDDLLDFSNDDGEVDDGLNTLPDSSTLSTGTLTDSSNSSSLFTDGTGFSDLYIPNDDIAELEWLSNFVEESFAGEDQDKLHLFSGLKNPQTTGSTLTHLIKPEPELDHQFIDIDESNVAVPAKARSKRSRSAASTWASRLLSLADSDETNPKKKQRRVKEQDFAGDMDVDCGESGGGRRCLHCATEKTPQWRTGPMGPKTLCNACGVRYKSGRLVPEYRPASSPTFVMARHSNSHRKVMELRRQKEMRDEHLLSQLRCENLLMDIRSNGEDFLMHNNTNHVAPDFRHLI
What is the function of this protein?
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.  May be involved in the regulation of some light-responsive genes (By similarity).
What are the official names of this protein?
GATA transcription factor 9.
What is the protein family that this protein belongs to?
Belongs to the type IV zinc-finger family. Class A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRM5_USTMA
Sequence: MSISSCSAQDGCASTAMTRTAMRQNKFATSAPASVPRLTGTEPQLGSMQGAQELLEQLKASFTSSHLIQAIGLSGRQLPLLTKDQEILPYLFNAAGVRYVQPHPNGDASQRILLLNVPASSPTPDVVLSAILKHRLELIHEFELSLGYEHLSSDQILEALLPTSIVDTDGVPTGFTIVGHIAHLNLLSVYKPFRFLVGHIILSKHIGTLRTVVNKLDSIDTQFRFFEMELLAGEADFVAQVSESDCSFQFDFRSVYWNSRLHAEHMRLIKKCRPNQVLADVMAGVGPFAVPAAKRGTWVLANDLNPSSYESLTKNAEINKVLLREGEAKPDKDGGLVATCMDGREFVRWSMLEVWKRGFAGRPMGFDGEQFDVQDDKLRQSARKMRKEQAKKNRALYAVRQAENTLEGAAESLANLSVDEPDVAATMGQVERHPERKLVDHFVMNLPAIALEFLDAFRGAYTHLATIVGKQRLLCQLELHKLDASIHRLPMIHVHCFSKDPFTPALDILTRANEALNIPRDAPYRLMAKPILPPAQTFAGLRKLCDASQSASYLSSHPNYSKYKHLESQHDFMQYVHQEWLERDAAQHTPNLSIHYVRDVAPNKQMYCLSFQCPSQVLWANTSTSQHT
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: RNY_STRPB
Sequence: MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEAVDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQLETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELEKVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAGEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPIRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDREVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARNESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVREKIENNLDYPGNIKVTVIREMRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y2548_DEIRA
Sequence: MAGHSKWAQIKRKKGANDKKRSAMYSKHIRAIQAAVRSGGSGDPAGNLSLKNAIAAAKTDTVPADNIENAIKRAVGAGEGAAEYKEQTYEGYGPGGTAIFIETLTDNVNRTVADIRAVFNKRGGSMGNSGSVAWQFEKKGIILLRDASEAAQEVAIENGAEDIQESDEGLEISTAPNDLYAVQDALSAAGYAVESGQITMLPTNTVAVAGDDARKLLTLVEYLEELDDVQNVYTNADLPEDEED
What are the official names of this protein?
Probable transcriptional regulatory protein DR_2548.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_STAA9
Sequence: MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EFTS_THEAB
Sequence: MIDAKLVKELRDRTGAGMMDCKKALEEANGDMEQAIEILRKKGIAKAAKKASRETGDGIIAAYVHFNKRIGVLVELNCETDFVARTEDFQELGNKIAMHIAAMSPRWVRREDVPQEVIEKEKEIYRDQLKDSGKPEHVIEKIVEGKLNKFFEENCLYEQKFAFDEDKTVEELIKESIAKIGENIRVSRFVKYTVGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMC1_MOUSE
Sequence: MLQIQVEEKEEDTEESSSEEEEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFVLTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGLSGNTTGAPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ
What is the function of this protein?
Probable ion channel required for the normal function of cochlear hair cells.
What are the official names of this protein?
Transmembrane channel-like protein 1, Beethoven protein, Deafness protein, Transmembrane cochlear-expressed protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized to the stereocilia of the cochlear hair cells.
Protein: RL11_CHILA
Sequence: MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.  Promotes nucleolar location of PML.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PYRB_OENOB
Sequence: MANVFVNINDLSNQELLSMIHQALLFKSGQFIPVINRQVVANLFFENSTRTATSFQMAEMKLGYQRIVIDPNKSSATKGESLEDTLKTLKAIGIDTIVIRHSLRDWYQPFYEMAGKEVPKLVNAGDGNGQHPSQSLLDLMTIVEHFENFVGLRVRIIGDIYHSRVARSNAEILNRLGVEVTFSGPKEWQDQSLEQFGSFVGIDKDLGKQDVIMLLRVQHERLTDEENQDFTIDKYHEDYGLTQDRYRKLKSNAIIMHPAPVNRDVEIDSDLVESDKSRIFQQMKNGVYARMAILNSLTIPSLISGVGK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.