PharMolix/UniProtQA huggingface dataset:
Protein: DRS8_PHYSA
Sequence: MDILKKSLFLVLFLGLVSLSICEEEKRENEDEEKQEDDEQSEMKRALWKTMLKKLGTVALHAGKAALGAAADTISQGAQ
What is the function of this protein?
Potent antimicrobial peptide with activity against bacteria, fungi and protozoa.  Probably acts by disturbing membrane functions with its amphipathic structure.
What are the official names of this protein?
Dermaseptin-S8, DRS-S8, Dermaseptin DS VIII.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SCPB_SYNC1
Sequence: MDTVELKAIIEALLFAAPGPVRLEQLALAADADPARVAPLLAELETEYLRAGRGFVLVELAEGYQLRTRPEHAEWVRRLHSSRPTRLSRAALEALAIIAYQQPVTRADIDYLRGVDSGGVVKSLLDKRLVRIVGKKDVPGRPLLYGTSREFLEFFGLRSLSDLPTLKEFTELTKESESLLFDFDAGAGGATASSEQA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: ACNA_CORDI
Sequence: MTESKNSFNAKQTLEVGDKSYDYFALSAVKGMEKLPYSLKVLGENLLRTEDGANITADHINAIANWDPSAEPSIEIQFTPARVLMQDFTGVPCVVDLATMREAVKTLGGDPDKVNPLNPAEMVIDHSVIIEAFGSTLALAKNVEIEYERNEERYQFLRWGSKAFSNFRVVPPGTGIVHQVNIENLARVVFDNNGLAYPDTCIGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLTGEIPAGVTATDVVLTITEMLREHGVVQKFVEFYGNGVKSIPLANRATIGNMSPEFGSTCAIFPIDEETVKYMHLTGRSEEQVALVEAYAKAQGMWLEQDAPEAEYSEYLELDLSTVVPSIAGPKRPQDRILLTEAKEQFRKDLPDYCSAEPVDESLPAKRMDSEGAVQKEGEDVAGYNSSRAGHGESAAEGAAGRQSNPVVVSSPNGGEYTLDHGMVAIASITSCTNTSNPSVMIGAGLIARKAAAKGLKAKPWVKTICAPGSQVVDGYYKRADLWKDLEALGFYLSGFGCTTCIGNSGPLPEEISAAINENDLTATAVLSGNRNFEGRISPDVKMNYLVSPIMVIAYAIAGTMDFDFETQPLGQDIDGNDVFLKDIWPSTEEIEETIAGAISRELYEADYADVFKGDEQWQNLPTPEGKTFDWDEKSTYIRKAPYFDGMTMEPAPVSDIKGARVLAKLGDSVTTDHISPASSIKPGTPAAQYLDENGVARNDYNSLGSRRGNHEVMMRGTFANIRLQNQLVDIAGGYTRDFTKNGEQAFIFDACQNYKAAGIPLVVIAGKEYGTGSSRDWAAKGTNLLGVKAVITESFERIHRSNLIGMGVIPLQFPAGESHASLGLDGTETFDIEGIEELNNGVTPKTVHVTATKESGDQVEFDAVVRIDTPGEADYYRNGGILQYVLRNMINA
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: CUSC_ECO57
Sequence: MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVNAADNYQNAGWRTFFVDNQVKTLISEALENNRDLRMATLKVQEARAQYRLTDADRYPQLNGEGSGSWSGNLKGDSATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRAVHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQARGVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQILLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTVLDLNYARQVNEISLYTALGGGWQQ
What is the function of this protein?
Forms pores that allow passive diffusion of cations across the outer membrane.  Part of a cation efflux system that mediates resistance to copper and silver (By similarity).
What are the official names of this protein?
Cation efflux system protein CusC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein. Cell outer membrane; Lipid-anchor.
Protein: RRP5_HUMAN
Sequence: MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDISTEEGSTKRKKSQKGPAKTKKLKIEKRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYTKKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLSAEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLNCIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNFLTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLSCQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNVFNPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLVPPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAKPGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCEPSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNIRAFLPTSHLSDHVANGPLLHHWLQAGDILHRVLCLSQSEGRVLLCRKPALVSTVEGGQDPKNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVAAKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNRDSVLIQTLAEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVDLLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVDEDEEVDPALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTTKLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPMEKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVGQALRATVVGPDSSKTLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSIFHMSDSYSETPLEDFVPQKVVRCYILSTADNVLTLSLRSSRTNPETKSKVEDPEINSIQDIKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSVLED
What is the function of this protein?
Involved in the biogenesis of rRNA.
What are the official names of this protein?
Protein RRP5 homolog, NF-kappa-B-binding protein, NFBP, Programmed cell death protein 11.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2226_MYCTO
Sequence: MPVEAPRPARHLEVERKFDVIESTVSPSFEGIAAVVRVEQSPTQQLDAVYFDTPSHDLARNQITLRRRTGGADAGWHLKLPAGPDKRTEMRAPLSASGDAVPAELLDVVLAIVRDQPVQPVARISTHRESQILYGAGGDALAEFCNDDVTAWSAGAFHAAGAADNGPAEQQWREWELELVTTDGTADTKLLDRLANRLLDAGAAPAGHGSKLARVLGATSPGELPNGPQPPADPVHRAVSEQVEQLLLWDRAVRADAYDAVHQMRVTTRKIRSLLTDSQESFGLKESAWVIDELRELANVLGVARDAEVLGDRYQRELDALAPELVRGRVRERLVDGARRRYQTGLRRSLIALRSQRYFRLLDALDALVSERAHATSGEESAPVTIDAAYRRVRKAAKAAKTAGDQAGDHHRDEALHLIRKRAKRLRYTAAATGADNVSQEAKVIQTLLGDHQDSVVSREHLIQQAIAANTAGEDTFTYGLLYQQEADLAERCREQLEAALRKLDKAVRKARD
What are the official names of this protein?
Uncharacterized protein MT2285.
Protein: RL27_RALPJ
Sequence: MAQKKGGGSTRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRTHAGVNVGMGKDHTLFALVDGHVKFANRGEGKKQFVDVVPAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CEP3_VZVD
Sequence: MGQSSSSGRGGICGLCKRYNELVTCNGETVALNSEFFEDFDFDENVTEDADKSTQRRPRVIDVTPKRKPSGKSSHSKCAKC
What is the function of this protein?
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes.  Participates also in viral entry at the fusion step probably by regulating the core fusion machinery.
What are the official names of this protein?
Cytoplasmic envelopment protein 3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 3 family.
What are the subcellular locations of this protein?
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: T176A_HUMAN
Sequence: MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI
What are the official names of this protein?
Transmembrane protein 176A, Hepatocellular carcinoma-associated antigen 112.
What is the protein family that this protein belongs to?
Belongs to the TMEM176 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DXR_FRAT1
Sequence: MFKKTKITILGATGSIGDSTLAVIRETNDFEVFALTAFSNVEKLAELCQEFKPKFAVVPDLSKKQKLQSLVTDVEVLVGESGLEKVSSLAEIDIVMSAIVGIAGLKPTFAAAKAGKKILLANKESLVTAGHLLIDEVVKNNAQLIPVDSEHNAIFQCIDNHDKKCLPEIDKIILTASGGPFRDKQLHELTDVTPEQACNHPNWQMGRKISVDSSTMVNKALEVIEAYWLFSVSADKIGVLIHPQSVTHSMVRYVDGSYIAQLGVPDMKTPIANAMYYPKRGSVNVESLDFTKYQLTFREACFERFEALKIVFNNLQNKNYAANIVFNAANEELVAAFLNKKIKYLEIIEVNKKVTKELNFENPKNIEEVFEIDRKTREYVDSVLG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RECR_LEGPC
Sequence: MDALSRLVEALRCLPGVGPKSAQRMVFHLLQHQRQRGLHLASCLEQAMKHISHCQQCNNYTEQTLCTLCQNPNRDSTLLCVVESPADVSAIEQSNSFQGKYFVLMGKISPLDGLGPDDIGLPKLKELIIREKIQEVILALSPSVESQTTIHFIHQLLKDETVNISQLAHGIPSGGELEFLDGNTISSALKNRAVINV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RIMP_DICNV
Sequence: MSQEQVVTELLRPIVESMGFIWWGLEYHYNSMNSILRIYVDTQEGGIGIDDIVTITEQLNPILDVEQPITTNYTLEVSSPGLDRILFTLAQCEQFIGATVHCRLRFPFEGKRKFQGIMTAVDHDKETISLTLADGAAEVHLPFTQIDKARIVPQF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA0_PODAS
Sequence: MGGKSANKAGYFDKLKGLLEEYKSIFIVSVDNVSSQQMHEIRQALRDQGVVLMGKNTMVRRALKTFLVDSPEYERLLPFVKGNVGFVFTNGDLKEIRDKILANKVAAPARAGAVAPVDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGAKVGPSEATLLNMLNISPFTYGMGIAQVYDQGNTFPSSVLDISEEQLLKAFSSAITTIAAVSLALNFPTLPSVIHSLVNSYKKVLAVAIETEISWPEIEELKDRIANPEAYAAAAPVAAADSGAAAGGAAAEEEKEEEEESDEEGGFGDLFG
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL32_NEIM0
Sequence: MAVQQNKKSPSKRGMHRSHDALTAPALSVDSTTGEVHRPHHISPNGMYRGRKVVKAKGE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SRRT_DANRE
Sequence: MGDSDDEYDRRRRDKFRRERSDYDRSREREDRRRDDWNDRRPSAREWDRGRERRSRGEYRDYDRGRRERFSPPRHDMSPQQKRMRRDWDDHGGDPYHGGYDLGYGGGGGPSYAPPQPWGHPDMHLMQPHHGIPIQARLGNIHDMDLGPPPPVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILEQPSEEEEERERLSSGGTPSEPSKRDEPKPADTENKPSEEKDKMEEGEESAEKDGEKASAGGSEGEEKTEKEAPAEPIPEPKKLSKKRKRKHSGDSEDEASASESESDSDSDSNSHCSEKPSEREREPEEVEEKEEEEEEEGEAADGKEQTDEQTEREKEKEKKVKDDQPPRPRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREETPTLELPAQNPILKNITDYLIEEVSAEEEELLGSAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGPIPPNRITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPEMKPPPHPGPGQGVLSPGGLPFPPQGPQGLMGFGQPRPPLMGYGGGPPYPPNQYGGGRGNYDNFRGQGGYPGKPRNSRVMRGDPRNIIEYRDLDAPDDVDFF
What is the function of this protein?
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation.  Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity).  Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal.  Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
What are the official names of this protein?
Serrate RNA effector molecule homolog, Arsenite-resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ARS2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similarity).
Protein: UBP15_HUMAN
Sequence: MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFSIPDEKETRLWNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPKSPGASNFSTLPKISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMDENLSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLMAVPRNNTEDKLYNLLLLRMCRYVKISTETEETEGSLHCCKDQNINGNGPNGIHEEGSPSEMETDEPDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEDTCKGQLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFPLDRETKGASAATGIPLESDEDSNDNDNDIENENCMHTN
What is the function of this protein?
(Microbial infection) Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 15, Deubiquitinating enzyme 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15, Unph-2, Unph4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: COX2_BRAFL
Sequence: MATPAQLGLMDAASPVMEEMIYFHDHVMLVLILITCLIFYSMLVLISSKYIYRFLTDGHVIETVWTVIPAIILVVVALPSLKLLYLTDELDNPQLTIKSVGHQWYWSYEYTDYYDIEFDSYMLPLGDLSKGDARLLEVDNRVVLPVDTSVRVLVTAADVIHSWTVPSLGLKMDAVPGRLNQLALQCSRVGTFYGQCSEICGANHSFMPIVIEAVPVEVFEGWCDMMLDEE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NCF2_RAT
Sequence: MSLAEAIRLWNEGVQAADKKDWKGALEAFSEVQDPHSRICFNIGCMYTILDNLQEAEQAFTKSINRDKHLAVAYFQRGMLYYSMEKYRPASVGRKAALLFLGSYNLVARIIVGYPLSPGKVLYNIALMHAKKEEWKKAEEQLALATNMKSEPRHSKIDKAMESIWKRCPTSHLPLDPPQVTMALWFEEGGVGKRSVVASVVHQDNFSGFAPLQPQSAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSLESDIPPPPNSSPPERLQLSPGWCQQLGPLRCPPFLLHQEVKRSVPMPYMLKVHYKYTVVMETQLGLPYSQLRNMVSKKLELLPEHTKLSYQRRDSPELLLLSEESMKDAWAQVKNYCLTLWCEHTVGDQGFVDEPKEKENSDADNRTTEPQPKEGTQVVAIFSYDATQPEDLEFVEGDVILVLSHVNEEWLEGECKGKIGIFPKAFVEGCAAKNLEGTPREV
What is the function of this protein?
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
What are the official names of this protein?
Neutrophil cytosol factor 2, NCF-2, Neutrophil NADPH oxidase factor 2.
What is the protein family that this protein belongs to?
Belongs to the NCF2/NOXA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYD_SHIFL
Sequence: MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHHDHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH
What is the function of this protein?
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step.  This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD, PPIase, Metallochaperone SlyD.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: RS213_FRATO
Sequence: MPRIIVDPKKPFDISLRNFKRACEKAGIKQELRDRQHYVKPTQKRKIAKKAAISKAKKEARRSYSY
What are the official names of this protein?
30S ribosomal protein S21 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RK18_CYACA
Sequence: MINDIKQLHKRYRLLVHLSNNHVYAQIIDDLNNRTVLSVSTLTPQVKSKLSITCNKKAAELVGEYVAQQALNFGIRNVVFDRGRKLYHGKVEVLANSARSFGLKF
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGR_BIFLD
Sequence: MSETGPSLQRPATRAARLSAIEQALATHIITSQSQLSKILIDEGIAVTQATLSRDLDEMHAVKTRLKDGTVAYAVGRSVVASEGEDVGERGEAQMSRVLNGLVTSVAAAGNLVVVHTPSGAAQYVASVIDKQPIEGVLGTIAGDDTVMVICTNDDTAVSRSDWLLSLASK
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRP3_ACRHI
Sequence: GPSSGFFGMR
What are the official names of this protein?
Tachykinin-related peptide 3, TKRP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIC_AZOSB
Sequence: MQHPASGESWLARPPRTAERRLRPWLTDPASLTARIRMRCGMFGVRVLRQSAGALTPDERRLLGLRAGERALLREVLLIADGRPVVFARSVLAQREQRGGWLRLWRGIGSRPLGAALFSDPRIRRQPLACARIGAADARYHLARRALAGAATLPPALWARRSVFRLHGRSLLVSEFFLPAILGLPDDPL
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_META3
Sequence: MEIEKMIKQLNPKFRNIDGKKLLIAIAIDEDKTVLMTAFMDEEALKTTLETGYMHYYSTSRDKIWRKGEESGNVQKVKEIYADCDKDALLFVVEQKGWACHENYYTCFHYKLNLKNNDIEIVGENMVNKY
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_PORG3
Sequence: MAKEHFNRSKPHVNVGTIGHVDHGKTTLTAAITTVLAKRGLSELRSFDSIDNAPEEKERGITINTSHVEYQTANRHYAHVDCPGHADYVKNMVAGAAQMDGAIIVVAATDGPMPQTREHILLARQVNVPRLVVFMNKCDMVDDEEMLELVEMDMRELLSFYDFDGDNTPIIRGSALGALNGEPQWEDKVMELMEAVDNWVPLPERDIDKPFLMPVEDVFSITGRGTVATGRIETGIVKTGDEVQIIGLGAEGMKSVVTGVEMFRKILDEGQAGDNVGLLLRGIDKDQIKRGMVISHPGKITPHKRFKAEVYILKKEEGGRHTPFHNKYRPQFYIRTLDVTGEITLPEGTEMVMPGDNVTITVELIYPVACNVGLRFAIREGGRTVGAGQITELID
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER1_PSEAE
Sequence: MTFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPENMQEFIELNSELAEVWPNITEKKDALPDAEEWDGVAGKLQHLER
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin 1.
Protein: KCY_STRP6
Sequence: MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTDKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLVIRQNDVTNNVSWVSALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.