PharMolix/UniProtQA huggingface dataset:
Protein: IVOC_EMENI
Sequence: MLSLDLVFSFPAWALLLVLTLLYTLYLATTRLLLSPIRHIPGPTLAALSFWPEFYYDVVQRGQYFRQIDKMHQTYGPLVRINPFEIHIQDPSFYPVLYTGPTRRRHKWLWAARMFGNNTSAFATVRHEHHRLRRSALNPLFSKSAIQRLTPHLQHTLARLCSRLDGFAFTRQDVDLGIGLTAFAADVITEYCFGQSLELIGKDNFGKEWIDMVSAPSELGHLVKQCPWILVVCKWAPKALVRALLPGVALLFQIQERMSAQIQPLVDRAAAVDKPADPLTVFDFLLSSTLPQHEKTVDRLKGEGQTLIGAGTLTTGNALKTIIFHVLNDPDIFRKLRAEVDGALENMDILSMSDTAYLERLPYLSACIKEGLRISYGVTHRLQLIAEEPLIYSGVTIPAGTPVGMTSIFMHDNPVVFPQPREFRPERWFEADFETVQAMNRHFVPFSKGSRMCLGMNLAYAEIYLVLAVLFRRYEISLSGVTREDIEMAHDFFDPAPKEGARGLIVQLQKRG
What is the function of this protein?
Nonribosomal peptide synthetase; part of the pathway that mediates the biosynthesis of the gray-brown conidiophore pigment (PubMed:23617571, PubMed:28108400).  The first step of the pathway is performed by the nonribosomal peptide synthetase ivoA that catalyzes ATP-dependent unidirectional stereoinversion of L-tryptophan to D-tryptophan with complete conversion (PubMed:31573806).  While the stereoinversion is catalyzed by the epimerization (E) domain of ivoA, the terminal condensation (C) domain stereoselectively hydrolyzes D-tryptophanyl-S-phosphopantetheine thioester and thus represents a non-canonical C domain function (PubMed:31573806).  D-tryptophan is acetylated, probably by an endogenous acetyltransferase (Probable).  N-acetyltryptophan is further 6-hydroxylated into N-acetyl-6-hydroxytryptophan (AHT) by the cytochrome P450 monooxygenase ivoC (PubMed:28108400).  N-acetyl-6-hydroxytryptophan is substrate of the N-acetyl-6-hydroxytryptophan oxidase ivoB to produce the gray-brown conidiophore pigment (PubMed:2126551, PubMed:28108400, Ref. 3).
What are the official names of this protein?
N-acetyltryptophan 6-hydroxylase ivoC, Benzoate 4-monooxygenase, Cytochrome P450 monooxygenase ivoC, Ivory mutation-related protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RFNT_BRUA4
Sequence: MTDATAARRNIVILTIAQALGASSPPIVISLGGLVGQKLSSDPALVTLPVSLFNLGLALGTLPAAFFMRQFGRRNAYMLGALVGAAAGVIAAAGIFAASFLIFCLGTLTAGFYASYVQSYRFAATDAATGDMKARAISWVMVGGLVAAIVGPQLVIWTRDTIPDAMFAGSFLSQAVLGLLALPVLFMLRAPKVRKDPNAIHDTGRPLGEILRSPRFILSVAAGVCSYALMTFVMTAAPIAMVGHGHSVDHAALGIQWHVLAMFAPSFFTGKLITRFGKEKITALGLVLIAFSAIIALGGFDVGHFWGALIFLGIGWNFGFIGATAMVTDCHTPAERGKAQGANDFIMFGTVACASFFAGSLLHSSGWETINWLVFPIVALVLVPLILRLKPKGAAAEA
What is the function of this protein?
Transports riboflavin into the cell.
What are the official names of this protein?
Riboflavin transporter RfnT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHEB3_BURO1
Sequence: MNIGIVNDLPLAVEALRRVIALRADHRVLWVATDGDEAVDFCVAHPPDVVLMDLVMPKVDGVAATRRIMARAPCAILIVTASVSANTSSVYEAMGAGALDAVDTPTLALGLSTDASPQALLAKIDQIGRLLESRTTALVPPGPAPTRGQPTLVAIGASAGGPTALTALLRALPADFPAAIVIVQHVDQAFAYGMAEWLDGYTRLPVRVARQGSVPEAGAVLLAATNDHLMLSPRGVLGYTRHPAETPYRPSIDVFFNSVADGWQGDALGVLLTGMGRDGALGLKAMRAKGCYTIAQDQATSAVYGMPKAAAAIGAASAILPLDQIAPQLIARIALTSRD
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
Protein: RL21_SYNFM
Sequence: MYAVLKSGGRQYEVRPGQVVKVEKLLGEVGDKVTLDQVLLFSDGTDIQVGQPVLANIAVQGQIVEQGRHRKIVIFKHKRRKDYRKKQGHRQHYTAVRVEEIVTLGQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PONE_DICDI
Sequence: MQTFKKLILILLLLALFVFSNGQYTFNVLNKAPGSKCENGTMAELNTCSKDCLTSFLILKSIDKKSLTFTTFNNNQCNGDYNTQTTFDCKPTPQNISQTQYFISCEEQTSKPTSSPIHSNSTIKSTSTTTTSTPLPHKDTPHHSASSSSIVVRLTPIFFIAFASLIFLFGF
What are the official names of this protein?
Ponticulin-like protein E.
What is the protein family that this protein belongs to?
Belongs to the ponticulin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CIDA_STAAS
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MINE_ALIF1
Sequence: MALLEFFRPQKKATANIAKERLQIIVAERRNGGPAPSYLPQLKEDILKVISKYVEVNPDMVTVSLEQKEEDLSVLELNVTLPDEDDH
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PRMC_MYCMS
Sequence: MNNTIFNVLNKIKNTNISLNKADVYHILEHIINKDYQWIISNLDHKLTKKQIYKIDQILDLLKQNYPLAYILKSKYFYSNIFFVNKDVLIPRNESELIIDHVSEFVKNNNDLLIVDLCTGSGCLGISCALLNDQNKVILTDISYKSLKVANKNIKKFNLINTSCLNGNFIDVLIKNNLKANLIICNPPYIDINDQNIDKNVIDFEPSIALFAPNKGLYFYEILIKNIDKIVDTNKNFLIVLEFGWLQKDSIEQLLINNCLKYKWEFKKDYNDYWRNLIIKNF
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: MTMR7_MOUSE
Sequence: MEHIRTPKVENVRLVDRVSCKKAALGTLYLTATHVIFVENAPDTRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIVQLVIPQERDCHDVYISLIRLARPVKYEELYCFSFNPKLDKEEREQGWLLVDLSEEYKRMGLPDNYWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYCKDSHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFIYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLTEQFPCAFEFNERFLTHIQHHVYSCQFGNFLCNSQKERRELKIQERTYSLWSNLWKNRADYLNPLFRADHSQTQGSLHLPTAPCNFTYKFWNGMYNRFEKGLQPRQSVTDYLMAVKEESQQLEEELESLEERLEKIQKVHLHGTKVKSKQSEPSKHSGFSTSDHSTANTPQDYSGNSKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSVNSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA
What is the function of this protein?
Phosphatase that specifically dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and inositol 1,3-bisphosphate (Ins(1,3)P2).
What are the official names of this protein?
Myotubularin-related protein 7, Inositol 1,3-bisphosphate phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Note=May partially localize to endosomes and/or the Golgi apparatus.
Protein: EDS1_YEAS1
Sequence: MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEKGTKQRKKASRACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRASVVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQFVKVPYDDIKRRSSLATLGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEEMGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQCMLTPNSVRSIEKERLNSLTAGCPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTEKNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDPEKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYYIQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLLLGPSVGVFNEFQAHKLFLPFENTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDTLQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFVLNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQKNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYFAQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIPTTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVSATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCCCCFFN
What are the official names of this protein?
Transcriptional regulatory protein EDS1, Expression dependent on SLT2 protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTZ2_ARATH
Sequence: MSYVTDFYQAKLKLYSYWRSSCAHRVRIALTLKGLDYEYIPVNLLKGDQSDSDFKKINPMGTVPALVDGDVVINDSFAIIMYLDDKYPEPPLLPSDYHKRAVNYQATSIVMSGIQPHQNMALFRYLEDKINAEEKTAWITNAITKGFTALEKLLVSCAGKYATGDEVYLADLFLAPQIHAAFNRFHINMEPFPTLARFYESYNELPAFQNAVPEKQPDTPSTI
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase Z2, AtGSTZ2, GST class-zeta member 2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Zeta family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: YBEM_ECOBD
Sequence: MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL
What is the function of this protein?
Hydrolyzes deaminated glutathione (dGSH) to 2-oxoglutarate and L-cysteinylglycine (specific activity 40. 63 umol/min/mg), very little activity against alpha-ketoglutaramate (a-KGM, specific activity 0. 178 umol/min/mg) and no activity on glutathione or L-glutamine.  May function as a metabolite repair enzyme.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1, ecYbeM.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: HSTXA_HAESL
Sequence: MMRTLLVFLLLAILAAVLIGNIQVEACKVLTDCNHSNAHSRCIKGRCVLMPG
What is the function of this protein?
Leech salivary gland peptide with unknown function.
What are the official names of this protein?
Peptide HSTX-X.
What is the protein family that this protein belongs to?
Belongs to the annelide toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_SYNPW
Sequence: MSLDTTEKQELINAHQTHATDTGSAEVQVAMLTERISKLSSHLQQNIHDFSSRQGLLKMIGRRKRLLGYVRGKSEKRYSDLIAKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CLPA_FUSBL
Sequence: MRPRSNAGSSPPDPEEQEHAQVPSFSSTLEQAIHAALALANARRHELATLEHLLLALIDEPDAARVMKACSVDLEDLKKTLTDFIDDDLSTLVTSVEGSEAVPTAAFQRVIQRAAIHVQSSGRTEVTGANVLVAIFAERESNAAYFLQEQDMTRYDAVNFIAHGVAKDPSYGESRPVQGADEPQETPKAEAGEAKESALSKYCVDLNIKARKGDVDPLIGREAEVERAIQVLCRRRKNNPLLVGDPGVGKTAIAEGLAWKIIKKEVPEVLSGATIFSLDMGALLAGTRYRGDFEERLKAVVKELEDHPDAILFIDEIHTVIGAGATSGGAMDASNLLKPALQGGKLRCMGSTTYKEFRQHFEKDRALSRRFQKIDVNEPSVPDAIKILMGLKPHFEEHHELRYTADAIKSAVELASRYINDRKLPDSAIDVIDEAGAAQHLVSDSKRKKVLGTKEIEAVVAKIARIPPRNVSKDDAETLRDLERTLKRLVFGQDKAIEALSASIKLARAGLREPEKPIGNYLFTGPTGVGKTEVAKQLAATLGVELLRFDMSEYMEKHAVSRLIGAPPGYVGFDQGGMLTDGVDQHPHCVLLLDEIEKAHPDVYNILLQVMDHGKLTDHNGRAVDFRNVILIMTSNVGAADMAKEAIGFGRERRTGEDTAAVERTFTPEFRNRLDAVISFAPLGREIILQVVEKFVLQLEAQLIDRNVHIELTPEAAAWLGEKGYDDKMGARPLGRVIQEHIKKPLAEELLFGKLTKGGLVKVGVKDDAIVLEVQEPQKPRLTGQKPPLLTAE
What are the official names of this protein?
ClpA homolog protein.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
Protein: URE3_BURTA
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPETIAFITAALMEAARDGKTVAEVMHYGTTLLTRDDVMEGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKH2_CANAL
Sequence: MSAQFITPKKRPHSPLDSNELLPSFEDPQDMINAVVSTLSAPEEKTNVSIAYANEKNQATEIQAYAKIAGKDWTFYVKSLAVSIGRNIELSAPSNTNITTPLIDIDLGPAKVVSRSHAAITYNLDLRCWELKVLGRNGARIDGQKVNVDSPNVNALHSGAILDIGGTQMMFILPDAPAVVAPKMLEKCLLRYKEQQQQQNKRISSGPGIGGSTSFQMFDKAHLTHSPSSISANSLQSNLDQDLSKEEAKDIKPPYSYATMITQAILSNPQGVMSLSEIYNWIADHYAYYKYSKTGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWQISESYKEEFLNKISDGTISKTRRGSSVSRQLSLHLATHNQLPESHKYTMDQQIHNGTAASIPQQQKQQQQQQKRPPQQQNSQPHLSQPHYTIPSNPMQTNSMGYIPQSNIYNMSNSDRRYTPYQQSQNPLMYQHQQQHIGQTYNQLGRPQGQLGQPMMQPQQQSYTSSNIKTEPSSPKRNPSISNNTPKMAKGTVSTESHSRSTSYTTTQLHEMSNFNSSANDSTSTAPTASTTTNGDIGLNFASPKKITALEAYTPERGSKGNPSGTNNNNNTNNTNTNTTNNNNGKNTAGGPNTNQSSPAFWNFVQFSTPNGQSPVRKSSEEVGNNSPTLNRKIKRERENDETNSPFKKKQRTEMIDS
What is the function of this protein?
Transcription factor required for the morphogenesis of true hyphal as well as yeast cells.  Contributes to virulence.
What are the official names of this protein?
Fork-head transcriptional regulator 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUFF_DROME
Sequence: MNSNYTILNIRAHSWAEKDNLVFPTITKPVSNGWFAWSPIGQFEPNSQKVPYVVVPPSIKFPISLRYKDSPPKLEKKPNIFLDNMLQYIESSSYMYVMVRNNQQAQLNANIVCTSEVLELMMCAPYEKKTGWSLGVTRYRNTMYICRIDVEQPDPIDQDNLKRAMQEFWLRNLRTHCVFENGIKMHQHNQSSEEHLRFHGVFSFDLNGNRVLFDSPVLAEMPSTTLNGSALSWVDLQIRPMFMSRLDWPEHNRTEALKWWVKCFLLGIESLYIARRDENAHVHNIEKTLVRDLWKSCEKDWSPTVCANFMIYLLNCISQVMAPIDCPSTVYLFQFDASQGTVSYKGLRGRNQYTFVSDWFRMMLDDHTNDMCKTPNLQTMSSIV
What is the function of this protein?
Involved in the piRNA pathway in germline.  tissues.
What are the official names of this protein?
Protein cutoff.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome. Note=Localized to perinuclear puncta in the nurse cells of younger egg chambers. Accumulates at centromeric/pericentromeric positions in germ-cell nuclei and strongly colocalizes with the major heterochromatic domains.
Protein: HSLU_BACHK
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLAENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGTQNSNQTTDSQEDVEIEKKRQDVERKLAAGLLEDEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKVLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSTDDFVKILIEPDNALIKQYMALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTAA_STAAB
Sequence: MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFNTKIVLTTGFILAFTSLFLVIWFPASPFIIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIANREKAK
What is the function of this protein?
Proton-coupled antiporter flippase that catalyzes the translocation, from the inner to the outer leaflet of the cell membrane, of the lipid-linked disaccharide (anchor-LLD) that anchors lipoteichoic acids (LTA) to the cell membrane.
What are the official names of this protein?
Proton-coupled antiporter flippase LtaA, Lipoteichoic acid protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LtaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FPR18_CAEEL
Sequence: MESQQLMACAILVIVLVGIFGNSLSFILFSRPHMRSSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLSTYMAYILKLIYPINLMMQTCSVYIMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVIIVSAFLYNFVRFFEYRFVVTESGALYEKWLRDPGKHRWYYVGYYTILYIVTHFLVPFSVMAFANGHVIVAMCKLSKTRQMLTRQQQREQSTTVMLLIVTFVFAICNTLPFLLNVSESIFPTLFQDESTRGLAYWLNDLSNLLVVLNSGTTFIIYFTFSEKYRQTLVFILKNGCCATVSDYNNYTAMSRTASMRISSETGGQIQRQGSKMSNSSRSSDVLLKPIYMQKRSERFSSEYNERTCKHLAPFEEHKLPKLPSEKRKKKLHKMSAVEHRGMPEITITFSEDLPDGEPDSPCQPC
What is the function of this protein?
G-protein coupled receptor for flp-2 neuropeptides (PubMed:15809090, PubMed:24533288).  May act through the G(q) alpha type of G proteins (PubMed:15809090, PubMed:24533288).  Involved in mediating arousal from the sleep-like state called lethargus, which occurs during molting between larval and adult stages, in part by regulating touch sensitivity, and working in concert with neuropeptide pdf-1 (PubMed:27585848).
What are the official names of this protein?
FMRFamide peptide receptor frpr-18, FLP2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPOL_HBVD1
Sequence: MPLSYQRFRRLLLLDDEAGPLEEELPRLADEDLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPHWKPPSFPNIHLHQDIIKKCEQFVGPLTVNEKRRLKLIMPARFYPNFTKYLPLDKGIKPYYPEHLVNHYFQTRHYLHTLWKAGVLYKRVSTHSASFCGSPYSWEQELQHGAESFHQQSSGILSRPPVGSSLQSKHQQSRLGLQSQQGHLARRQQGRSWSIRARVHPTARRPFGVEPSGSGHNANLASKSASCLYQSPVRTAAYPAVSTSENHSSSGHALELHNLPPNSARSQSERPVFPCWWLQFRDSKPCSDYYLSHIVNLLEDWGPCAEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGNYRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRIINHQHGILQNLHDSCSRNLYVSLLLLYKTFGWKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGCWGSLPQDHIIHKIKECFRKLPVHRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLNLYPVAEQRPGLCQVFADATPTGWGLVMGHQRMRGTFLAPLPIHTAELLAACFARSRSGANILGTDNSVVLSRKYTSFP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery (By similarity).
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: GST_HAEIN
Sequence: MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGDLVLSQNQAILHYLDELYPNSKLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAKDNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISVADAYLYIMLNWCKAVKIDFSHLTQLSAFMQRVETDQAVENVRKSEELKV
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT56_MOUSE
Sequence: MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAITLLEFKRHVGEQEDDTNLWIGYCAFHLGDYKRALEEYENATKEENCNPEVWVNLACTYFFLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMILAGREPKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium.  Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.  Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU (PubMed:22718903, PubMed:25340710).  Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components.  Not required for IFT complex A ciliary localization or function.  Essential for maintaining proper microtubule organization within the ciliary axoneme (PubMed:28264835).
What are the official names of this protein?
Intraflagellar transport protein 56, Protein hop-sterile, Tetratricopeptide repeat protein 26, TPR repeat protein 26.
What is the protein family that this protein belongs to?
Belongs to the IFT56 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Localizes at the base to the ciliary transition zone.