PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_STRPD
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAGDNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTAR1_PESFW
Sequence: MSSVPIDSVQAAQQVVSTKIKDKSWIMPTDPAEFLQQIAYQSQLLACLHWLGEFQILACVPLSGSVPIKDVADLAGVPVSQLAHVIRFMATAGFMKEPRRGEVAHTPQSAAFVTDPSFLDAGIFLAQVSARSARKMAQNSAISTLMGGDGANNGSDFDNGELLKSTSESPRVQREVTAYLHYVVNEVSDTANLLAQLDWRKLGSSSVVEIRADRIYPASLVLTELHSTPRFTVQTFQEDSVEQGTAVTTTATTSSSFISKSSEEPSPKRIKPGITYQKRSLGSPQVVTDATMYVMRLERPHSTSVQRSILDEGQIVSELRAHLGVLKHNSNATLILIGPLLPEAGAIDAKAEMVVRFRDLSLNQLTSEREMEVGELVDIIGDVQDESGCLVVVNKLYSRTSSTVALEVRYELYNYRKG
What is the function of this protein?
Transcription factor that, with ptaR2 and ptaR3, coregulates the expression of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).
What are the official names of this protein?
Pestheic acid cluster transcriptional regulator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTU2_HUMAN
Sequence: MCQVGEDYGEPAPEEPPPAPRPSREQKCVKCKEAQPVVVIRAGDAFCRDCFKAFYVHKFRAMLGKNRLIFPGEKVLLAWSGGPSSSSMVWQVLEGLSQDSAKRLRFVAGVIFVDEGAACGQSLEERSKTLAEVKPILQATGFPWHVVALEEVFSLPPSVLWCSAQELVGSEGAYKAAVDSFLQQQHVLGAGGGPGPTQGEEQPPQPPLDPQNLARPPAPAQTEALSQLFCSVRTLTAKEELLQTLRTHLILHMARAHGYSKVMTGDSCTRLAIKLMTNLALGRGAFLAWDTGFSDERHGDVVVVRPMRDHTLKEVAFYNRLFSVPSVFTPAVDTKAPEKASIHRLMEAFILRLQTQFPSTVSTVYRTSEKLVKGPRDGPAAGDSGPRCLLCMCALDVDAADSATAFGAQTSSRLSQMQSPIPLTETRTPPGPCCSPGVGWAQRCGQGACRREDPQACIEEQLCYSCRVNMKDLPSLDPLPPYILAEAQLRTQRAWGLQEIRDCLIEDSDDEAGQS
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2, Cytosolic thiouridylase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_STRPM
Sequence: MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFCFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_POLNA
Sequence: MPRRREVPKREILPDPKFGDVDLAKFMNVIMQGGKKAVAERIIYGALEQIEKKNPGKDPLEAFHMAIGNIKPMVEVKSRRVGGANYQVPVEVRPVRRMALAMRWLKEAAKKRGEKSMSLRLANELMEATEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: INSJ_SHIFL
Sequence: MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVALYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLKVYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMYLKKLKALAHPTKK
What are the official names of this protein?
Insertion element IS150 uncharacterized 19.7 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the IS150/IS1296 orfA family.
Protein: CYSD_MYCGI
Sequence: MTATDELTHNAGRYELSHLRALEAEAIHIIREVAAEFERPVLLFSGGKDSIVMLHLAVKAFRPGRLPFPVMHVDTGHNFDEVLQARDELVAETGVRLVVAKVQDDIDAGRVVETIPSRNPMQTFTLLRAIRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPELWNLYNGRHRKGEHIRAFPLSNWTEFDIWSYIGAEQIKLPSIYYAHERKVFERDGMLLAVHKYLQPRKDEPIIEKTVRFRTVGDVTCTGCVESTAATVSEVIAETAISRLTERGATRADDRISEAGMEDRKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ATPB_CLOBB
Sequence: MPGKIGKVVQVIGPVVDIKFDSDSLPNLYNAISIDMGERTLIAEVEQHVGDDIVRTIAMEATEGLKRGMDAVDTEKAISVPVGDQVLGRLFNVLGKPIDNAGEVEAEEIYPIHRPAPSFKDQAVEPEMFETGIKVIDLLAPYQRGGKIGLFGGAGVGKTVLIQELINNIAKEHGGLSVFTGVGERSREGNDLYHEMRESGVIDKTALVFGQMNEPPGARMRVALTGLTMAEYFRDKGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKNGSITSVQAVYVPADDLTDPAPATTFSHLDATTVLSRSIVELGIYPAVDPLESSSRILDPRLVGEEHYNVATKVKNILERYKELQDIIAILGVDELSDEDKAVVSRARKVQRFLSQPFTVGEQFTGMPGKYVSVKETIKGFKEILEGKYDDLPESAFLFIGSVEEAVQKAKSLA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PGA25_CANAL
Sequence: MKVTAVSSVLLTVAALTNANEIDKRSFFGDLFSGLTGSKAAAPAAAPAAQPAAQPTTQSPADQPTVQSPVSSDQPSTAQPVAQNNLLLDSSNSTLVVPSSSKSSTTTRSTAGLLDNLLGGSGATSSEASSSEAPSSEAPSSEAPSSEAPSSEAPSSEAPSSSSSEALSSSSTTKRPTAAAKGFFGDLFGTQSSASETDDEDCVEETESPTSAPASAPTTSKVATTTGGGLPNILSDLFPGKSSAPISSAESSPTVASSTTGFPNILSDLFPGKSSVPSSSAETSTTVASNTTTSGGGFPNILSDLFPGKSSVPSSSAEEDDEECEDPTESVTSNSSPTGGISIPTFPITSQSKTSVSSVVSKSTSEDDDDETECETDIPTIIPSGSVLPTTSVLPTIIPTGSGSITILPTKSATSDDDDDETDCETDIPTIVPTESATIIPTGSGSVTIIPTGSGSITVLPTKSATSDDDDDETDCETDIPTIIPTGTATIKPTGSGSITVLPTKSTTTDDDDDETDCETEIPTIHPTVSTTRTFTSDGVPTTQTLTTKLPPTTNQHTETEVVSITYTGGGQTFTTYLTQSGEICDETVTLTITTTCPSTTVAPGGQIYTTTVTVITTHTVYPDDWEDDGYEGEDNAGGSASGSSDDGEWEWYEEDDGECVPTGGSSSGSGTGSWWGSGAGSSGGTTSGSGSGSSSNSGASSGGTWGGSGNDYVCPGEEGYDDEEPDNGGSWWGGSGSGSSSGSSSGVSSGDSGSSSVTGGSSGSWWGGSGNDYVCPGEDGYDDEDDQTPEPECDDEDDSWDDDEECDTQAAKEVVNSVTVAAESVYPSTTAASLTTSWISTQTAQSVTQIENIGGKVSASGLFVVLGLLLI
What is the function of this protein?
Probable GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence.
What are the official names of this protein?
Probable GPI-anchored adhesin-like protein PGA25, Predicted GPI-anchored protein 25.
What is the protein family that this protein belongs to?
Belongs to the HYR1/IFF family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: LPTF_ECOL6
Sequence: MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
What is the function of this protein?
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
What are the official names of this protein?
Lipopolysaccharide export system permease protein LptF.
What is the protein family that this protein belongs to?
Belongs to the LptF/LptG family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BETB_CERS4
Sequence: MRAQPAASHFVDGRPLEDETGAPIPVIYPATGEEIARLHEATPAVIEAALASGARAQAAWAAMRPVERARILRRASDLIRAHNEELSLLETLDTGKPLQETLVADWASGADALEFFAGLAPVVTGETVPLGQDFVYTIREPLGLCVGIGAWNYPSQIACWKAAPALALGNAMVFKPSEVTPLGALKLAEILIEAGLPPGLFNVVQGRGAVGASLVTDSRVAKVSLTGSVPTGRRVYAAAAEGVRHVTMELGGKSPLIVFDDADLESAIGAAMLGNFYSAGQICSNGTRVFVQKGIKEAFLARLAERADAIRMGDPLDPEVQMGPLVSQAQLEKVLAYIEKARAEGGRLVCGGEASVSPGCYVQPTVFADVTDAMTLAREEVFGPVMAVLDFETEEEAIARANATDFGLAAGVFTADLTRAHRVVAQLQAGTCWINAYNLTPVEAPFGGVKLSGVGRENGRAAVQHYTQVKSVYVGMGPVDAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RL2_ECODH
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LPRP_MYCBO
Sequence: MKRTSRSLTAALLGIAALLAGCIKPNTFDPYANPGRGELDRRQKIVNGRPDLETVQQQLANLDATIRAMIAKYSPQTRFSTGVTVSHLTNGCNDPFTRTIGRQEASELFFGRPAPTPQQWLQIVTELAPVFKAAGFRPNNSVPGDPPQPLGAPNYSQIRDDGVTINLVNGDNRGPLGYSYNTGCHLPAAWRTAPPPLNMRPANDPDVHYPYLYGSPGGRTRDAY
What are the official names of this protein?
Uncharacterized lipoprotein LprP.
What is the protein family that this protein belongs to?
To M.tuberculosis LprP.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DPY19_CAEEL
Sequence: MAKKPKNSPEKSKYSSDTSSSLYSQTWLASVVIIGLLVGYINYQHVYTLFENDKHFSHLADFEREMAYRTEMGLYYSYYKTIINAPSFLEGVQEITHDTVTEHGHEINTLNRFNLYPEVILAFLYRPFRAFAKSANWQIELCWQVNRGELRPVESCEGIGNPHYFYITGVFIVAGTVASSIFYLGVLVSDSIFGGFLSVLCFAFNHGEATRVQWTPPLRESFAFPFIIGHIAILTFVIKYKKSGHSMILLLTSMAVPALLFWQFTQFAFFTQICSIFLAFSLDLIPFSTAKTVIHSHIISFLIGFLLLFGNEMMITALYFPSILALGMIIYISPLLSNLKFRPAYVLFLAIIFASITLGLKIGLSKGLGIEDDAHIFDILRSKFTSFANFHTRLYTCSAEFDFIQYSTIEKLCGTLLIPLALISLVTFVFNFVKNTNLLWRNSEEIGENGEILYNVVQLCCSTVMAFLIMRLKLFMTPHLCIVAALFANSKLLGGDRISKTIRVSALVGVIAILFYRGIPNIRQQLNVKGEYSNPDQEMLFDWIQHNTKQDAVFAGTMPVMANVKLTTLRPIVNHPHYEHVGIRERTLKVYSMFSKKPIAEVHKIMKEMGVNYFVFQLMNCSNDERRPECVYRGMWDEEDPKNSGRTALCDLWILAANSKDNSRIAPFKIVYNANRNYIVLKI
What is the function of this protein?
C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins such as unc-5 and mig-21.  Mediates the attachment of alpha-mannose in C-C linkage to the C2 of the indole ring of tryptophan.  C-mannosylation takes place in the endoplasmic reticulum and frequently found in thrombospondin (TSP) type-1 repeats and in the WSXWS motif of type I cytokine receptors.  Required to orient neuroblasts QL and QR correctly on the anterior/posterior (A/P) axis: QL and QR are born in the same A/P position, but polarize and migrate left/right asymmetrically, QL migrates toward the posterior and QR migrates toward the anterior.  Required with unc-40 to express mab-5 correctly in the Q cell descendants.
What are the official names of this protein?
C-mannosyltransferase dpy-19, Protein dumpy-19.
What is the protein family that this protein belongs to?
Belongs to the dpy-19 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NAS2_CAEEL
Sequence: MIFPLLLTLILPNFVAPKVLEPEKDDEIAVSTQREKTFFDMKLILTKLPTFEPSKYGHINIPLRKKRGIALHPLQWASYLWPNAEVPYDIATHYTSTEKSIILSAMEAFKNVTCVRFRPRAATDKHYLQINKYFNVERCFSYIGRQSSRTLFGTPEGNVETRMRLDPACLRGNGRGIVMHELMHILGFYHEHQRDDRDRRIVGSAVHYNFKIYRRAKTLYMGAYDANSIMHYNFQNLPWQRRDHFSTSDIININTFYKCKNLLSSKLAPKVPISPTSTSTTAITTTNTTTTKL
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-2, Nematode astacin 2.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_BUCAI
Sequence: MDDYKDTLNLPKTLFSMRGNLSKKEPNILKSWNENNLYKLIRKKNQEKKIFFLHDGPPYANGNIHIGHAVNKILKDIIIKSKNMSGFDAPYIPSWDCHGLPIEQKVEEKIKSNQGEISTTEFQEKCRKYAQDQVEKQKKDFIRLGVIGDWDNPHLTMNFKNEANIIKTLSKIVQKKHLYQDFKPIHWCLKCASSLSEAEIEYSKKKSDSIIVGFKFKYKSIIEKLFDFQISNKKEIHLLIWTTTPWTLPSSKAISIHPDFQYQLIETERCYLIIAKELVEKTLNTLKIKKSIIRNYVKGRFLEKMICLHPFLKNIDLPVILGKHVTLESGTGAVHTAPDHGLEDYIISQKYNIKTSNIVNFKGEYISNTHDKLDGVNVLEANSIIIELLIKNNTFFHHESLIHSYPHCWRHKSPVIYRATPQWFIDIDQKQLRIKLLQEIKKVRWIPEWGESRIGEMIKKRPDWCISRQRKWGVPMSIFIHKNTRKIHPNTFVFMKKIAKKVELEGLQVWWNIDSKEILGEEYQSYEKILDILDVWFESGNTHTTINYKNKNYTKKNADMFLEGSDQHRGWFMSSLIISTLISEKKPYSEVLTHGFVVDGKGQKMSKSIGNTISPNEIVDTLGADILRLWVASSNYSNDISISNEILKSSSDIYRRIRNTARFMLANISDFDPKKNIISKENMVLLDKWAIGQTKIVQEEIIQHYNNYNFHAVIQRLMYFCSIEMGSFYLDIIKDRQYTLKKHSQERRSSQTAIYYIINSLVRWIAPILSFTADEIWSYLPENNSQYVFMEEWFDKLFYLDQDDLFNYQFWNEIITIKHEINKFLEEAIQNKTINNSLETSIILYVSHELSNKLKILEQETKFIFLTSDIQIKLYDTAPKNAKKSKIVPYLKVSLEKIKGKKCPRCWHYFNFTKKNIKNSDICNRCILNTIGNGEKRIFI
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRP1_COTJA
Sequence: MPNWGGGKKCGVCQKAVYFAEEVQCEGSSFHKSCFLCMVCKKNLDSTTVAVHGDEIYCKSCYGKKYGPKGYGYGMGAGTLSTDKGESLGIKYEEGQSHRPTNPNASRMAQKVGGSDGCPRCGQAVYAAEKVIGAGKSWHKSCFRCAKCGKSLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALIHSQ
What is the function of this protein?
Heat stable protein, that interacts with zyxin/ZYX.  May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
What are the official names of this protein?
Cysteine and glycine-rich protein 1, Cysteine-rich protein 1, CRP, CRP1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the actin cytoskeleton.
Protein: GREA_BACP2
Sequence: MAQEKVFPMTEEGKLKLEEELEYLKTVKRKEVVERIKIARSFGDLSENSEYDSAKEEQAFVEGRITTLDNMIRNAKIIEDEGNSNIVSLGKTVTFVELPDGEEESYTIVGSAEADPFEGKISNDSPIAKSLLGKQVDDKVTVQTPGGEMFVQIVKIS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MIH_CALSI
Sequence: MMSLAHSKFSCQRTRLLAVVLLAALWSSSLQQAAARVINDDCPNLIGNRDLYKKVEWICDDCANIYRSTGMASLCRKDCFFNEDFLWCVRATERSEDLAQLKQWVTILGAGRI
What is the function of this protein?
Inhibits Y-organs where molting hormone (ecdysteroid) is secreted.  A molting cycle is initiated when MIH secretion diminishes or stops (By similarity).
What are the official names of this protein?
Molt-inhibiting hormone, MIH.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMI_FLAJ1
Sequence: MNKKVILMILDGWGKSPDPKVSAIDNANVPFINSLYKNYPSAQLRTDGLNVGLPEGQMGNSEVGHMNLGAGRIVYQDLAKINLAVAHKTLAKEQVLIDAFTYAKENNKKVHFLGLVSDGGVHSHTSHLRGLIDASQEYGLDQVYVHAFTDGRDVDPKSGAKYIHDLQDYIKDTPVKIASIVGRYYAMDRDKRWERVKLAYDLVVNGVGTPSTNPVSSVLESYEKDVTDEFIEPVVIVDENAKPLATIVEGDVVIFFNFRTDRGRELTEALSQHDFHEQNMHKLNLYYVTLTNYDETYQNVKVVYNKDNITETLGEVLEKAGKKQIRIAETEKYPHVTFFFSGGREIPFEGESRILRNSPKVATYDLQPEMSAYELADALVPELNKGEVDFVCLNFANGDMVGHTGIMEAAIKACEAVDACAKKVIDAALANDYTTIVIADHGNCETMINPDGSPNTAHTTNPVPIILVDKQLKNIQDGVLGDIAPTILELMGVQQPNAMTCHSLL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RBL_SOLTU
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMLTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGTPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIVFNFAAMDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL7_PSET1
Sequence: MSVSKDQILDAIAEMSVMDVVALIEAMEEKFGVTAAAGMVAGPAAEAVEEKTEFDVILTGAGANKVSAIKAVRSATGLGLKEAKALVEAAPTPVKEGISKEEAEALAKDLTEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TRMN6_SHIF8
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGL_MOUSE
Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLMALGSLAVTKNDGNYRGDPNWFMKKAQEHKRDFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
What is the function of this protein?
Actin cross-linking/gelling protein.
What are the official names of this protein?
Transgelin, Actin-associated protein p27, Smooth muscle protein 22-alpha, SM22-alpha.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_NEIG1
Sequence: MSEQNHPQTEPQLDENQIIALRREKLNNIRQQRNAYPNDFKRDSFAADLQAQYGEIGKEELDPQAVPVKIAGRMMLKRQMGKASFATIQDVTGQIQLYLNNKGVSQEVLDDFNHWDLGDIVGAEGTLFKTNHGELTVRVSDIRLLSKSLRPLPDKHKGLSDQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAEDIIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKSQVAQKDAGDDEAMHYDADYIRAMEFGLPPTGGCGIGIDRLVMLLTDLQTIRDVILFPQMRPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET1_PYRTR
Sequence: MPSLLLVVFILQLLLHIINTVGANTVNELLWVLYNKLPTPTSGSAQRCQVLKQDIVRLKRELGNTSPQDNFSKWAKLDRQHNKAMAEYQKLDGSLRSHQATFTSAVSTVRWLGTQGLRFVLQFWFSRSPMFWMPAGWVPYYVEWILSFPRAPLGSVSINVWGIACASIISLAAEATAAIWVLVTHKPTPMAAEKQREKQEAMAFSANQKPAEKEL
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RNY_OLEA2
Sequence: MGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQAHKKEVLIQGQDELFNQKRELEREFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDALSVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSEEAKARIFSEVEARTRHEAGKMIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNIRALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQELEVQLREVGEQATFDVGVHGIHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAELGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKYGESKDIIHAIAAHHEDVPPKSALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVLVNSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.