PharMolix/UniProtQA huggingface dataset:
Protein: ACSF_RUBGE
Sequence: MLATPTIESPEEAARRAKESTLLSPRFYTTDYAAMNAIDVSSIRAEWDAMLAEYEGDNNHDHFQRTPEFAQEVAERFSQVSPELRQEFLDFLVSSVTSEFSGCVLYNEIQKNVENPDVKALMRYMARNESRHAGFINQALRDFGLGINLGGLKRTKAYTYFKPKYIFYATYLSEKIGYARYITIYRQLERHPDKRFHPIFRWFERWCNDEFRHGESFALILRAHPHLISGANLLWVRFFLLAVYATMYVRDHMRPQLHEAMGLESTDYDYRVFQITNEISKQVFPISLDIDHQAFRAGMERLVRVKTKVDAAKARGGLVGRLQQAAWAAAGAATFARMYLIPVRRHALPAQVRMAPAW
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis in aerobic conditions.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: EFTS_HELPS
Sequence: MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVVPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHTTEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSFHIINGYAHSNARVGVLITIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDSKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPTFGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKEWDDHLTITEYVRFELGEGIEKKAENFAEEVALQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP1_CLOD6
Sequence: MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLPMGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTEREYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDAYSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGEDEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKFAKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAGPIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCIVCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAIIEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDERIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRNNVRLG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase 1, Prolyl-tRNA synthetase 1, ProRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARG13_NEUCR
Sequence: MDSVPAQTHQGFKEAGAASASHLTTTTSLPTKVESRTAVMEALEDIVYGSAAGIVGKYIEYPFDTVKVRLQSQPDHLPLRYTGPLDCFRQSIRADGFLGLYRGISAPLVGAALENSSLFFFERIGRSLLYSSGFAPRDSELSLSALWFTGGFSGAFTSLILTPVELVKCKIQVPDEPGGAGARQRQLKPIPVIKEIFRHEGLRGFWHGQLGTLIREAGGCAAWFGSKETTSKWFRGRNERALLKRGASQEEVVASRERPLPLWQQAIAGASAGMSYNFLFFPADTVKSRMQTSPIGGGGDNGGKGAATMMPKKSFGEEARALWKQAGIKGFYRGCGITVLRSAPSSAFIFMVYDGLKKYFPMA
What is the function of this protein?
Required for arginine biosynthesis.  May participate in the export of matrix-made ornithine into the cytosol (Potential).
What are the official names of this protein?
Amino-acid transporter arg-13.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS10_DESAP
Sequence: MQRQKIRIRLKAFDHHMLDQSAQKIVETVRRTGADVAGPVPLPTEKEIYTILRSPHKDKDSREQFEIRTHKRLIDILEPTPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MRAY_THEYD
Sequence: MLYEILYSLSDYISGLNVFKYITFRTMLAILTSFFFTFIIAPPCIRWLKKLSLTQHIRDDGPKTHLKKEGTPTMGGIIITASVLVAVLMWGNLKNHYMWIMIISFLGFGLIGFIDDYLKITRKNYKGLPGRYKLFAQLLLASSVTLFLYFNPKDPYTTVLSIPFFKQWLIDLGIFYLPFAIFVIVGSSNAVNLTDGMDGLAAGLVGIASIVNAVLLYISGHAVFAKYLYVLYIPGTGELAVFCGAMLGACLGFLWYNSYPAEVFMGDVGSLSLGGALGSLAVITKHEIVLALVGGIFVVEALSVILQVGYFKLTNGKRIFRMAPLHHHFELKKWPEPKVIVRFWIIGIILALLSLLTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_ROSDO
Sequence: MAITAAMVKELRDSTGAGMMDAKKALTENNGDMEAAVDWLRTKGLAKAAKKSGRTAAEGLVAVKVQGGHGVAVEVNSETDFVGKNADFQKMVAGIADVALGASDIDALRAADMGGKTVEQAVIDAVAVIGENMSVRRMSSIDGENVVSYVHNAAAPGMGKIGVLVATNGGDEAFGKQVAMHIAAVNPASLSEADLDPAVVEKEKQVQMDIARESGKPEQVIEKMIIGRMKKYMSEVTLLNQSFVVNPDLTVGDAAKEAGATITGFVRLEVGEGIEVVKEDFAAEVAKAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPB3_MOUSE
Sequence: MAKIILRHLIETPVRYQEEFEARGLEDCRLDHTLYALPGPTIEDLSKARGAGTPQALAEDSASTEKPPGEGKSRFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVETKDLSAILCHDGILVVEVKDSLGTK
What is the function of this protein?
Inhibitor of actin polymerization.
What are the official names of this protein?
Heat shock protein beta-3, HspB3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: C76AD_BETVU
Sequence: MDHATLAMILAIWFISFHFIKLLFSQQTTKLLPPGPKPLPIIGNILEVGKKPHRSFANLAKIHGPLISLRLGSVTTIVVSSADVAKEMFLKKDHPLSNRTIPNSVTAGDHHKLTMSWLPVSPKWRNFRKITAVHLLSPQRLDACQTFRHAKVQQLYEYVQECAQKGQAVDIGKAAFTTSLNLLSKLFFSVELAHHKSHTSQEFKELIWNIMEDIGKPNYADYFPILGCVDPSGIRRRLACSFDKLIAVFQGIICERLAPDSSTTTTTTTDDVLDVLLQLFKQNELTMGEINHLLVDIFDAGTDTTSSTFEWVMTELIRNPEMMEKAQEEIKQVLGKDKQIQESDIINLPYLQAIIKETLRLHPPTVFLLPRKADTDVELYGYIVPKDAQILVNLWAIGRDPNAWQNADIFSPERFIGCEIDVKGRDFGLLPFGAGRRICPGMNLAIRMLTLMLATLLQFFNWKLEGDISPKDLDMDEKFGIALQKTKPLKLIPIPRY
What is the function of this protein?
Converts L-DOPA to cyclo-DOPA in the betalain pathway.  Provides the cyclo-DOPA moiety of all red betacyanins.
What are the official names of this protein?
Cytochrome P450 76AD1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOI_SHIDS
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKTETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SLBA_TRIAB
Sequence: MGRFIFVSFGLLVVFLSLSGTGADCPSDWSSFKQYCYQIVKELKTWEDAEKFCSEQANDGHLVSIESYREAVFVAELLSENVKTTKYNVWIGLSVQNKGQQCSSEWSDGSSVSYENLVKPNPKKCFVLKKESEFRTWSNVYCEQKHIFMCKFLGSR
What is the function of this protein?
Weakly agglutinates platelets at high doses by binding to GPIbalpha (GP1BA).
What are the official names of this protein?
Snaclec alboaggregin-B subunit alpha, AL-B subunit alpha, 25-kDa alboaggregin.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SFSA_XANP2
Sequence: MRFPTPLIQGRLIRRYKRFLADVVLADGTETTVHVANSGAMLGLDAPGSRVWLSRAANLARKLPLSWELVEADFGAGAELVGVNTMHPNLLVAEAIAAGAVPALSGYARLRREVKYGLSSRIDIQLEDEARPLCLVEVKNVHLMRTPGYAEFPDCVTARGAKHLEELGAEADKGNRAVMVYLSQIGSARSIGLARDLDPAYGRAFDRARERGVEAIGLVCRIDPEGIEVADIIPMTG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MED11_XENLA
Sequence: MATFGMANERLRALEEIEREIAAILLNAGNAILELSKEKPNERMLDKQAAQFTASVQRVESELSGQIRYLTQVATGQPHEGSSYSARKDGTMALNRIDYSRVKLAELSRTCEQMLEQP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBK_PHYPA
Sequence: MLAIFNIYLDNAFHLNGIILAKLPEAYAIFDPIVDVMPIIPVFFFLLAFVWQASVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PNUC_ECOLI
Sequence: MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEKISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIRWLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFPFWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIALNGSRMWINSARERGSRALSH
What is the function of this protein?
Required for nicotinamide riboside transport across the inner membrane.
What are the official names of this protein?
Nicotinamide riboside transporter PnuC.
What is the protein family that this protein belongs to?
Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPP_FRATM
Sequence: MKVVEISHPMVKHKLGLMRAASISTQEFRRLTKEITSLLTYEVTAGFELEKIEILGWQGENIEIDQIKGKKLTVVPILRAGLGMMDGVFEHVPAAKVSMVGMYRDEKTAKPVAYFAKLCDKLDERVALIVDPMLATGGSMIATVSLLKKAGSKDIKIITLVSAPEGIDALAKAHPDVELYTASIDSHLNDKKYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: Y6611_BACAN
Sequence: MTYTKKKYTPKTKEQIKEETKEIMDKVLTDITKYYNSPEDMLELANFMAQFSNYSPRNMQLIKSQFPHAYACASFKTFKDAGFHVNKGEKAMKVFHPYVKEFVRDPKTKLPIPLTKLTAEQKQQVKNGELKVEKQTNYYLKATAFDISQTNASPEDLPKIFPNRQFNFEVTEENKELLKLGIQALAEKENIKIKDMGQGALIKELGTIHGAYVEVADSSFAQIVMNTRNTETKELSVAIHELAHAKLHNKKVASLEHVPTEEFEAELTSYIVCKHYGMDTSEASVPYIAEWTKNGQDIEEKDKSIMRVHETASSFINTIDKKISELQREREKNREQNKKEIEDVYVVRYGALTSTEEKIITVRELRERADRDKSYSDVENANTLNDKEYIEAFNKANEENCIALEHNEIKKLMVVIQWSEADLEKNKAIPFGEANAIMSKRIAEIDAESKRAEEKGEYVPYEKTRYHLILPKEMDKDFNRMEVVTMDRLDLGDGIYKSPYEQILNEKRQLSDEVKQALQQEINEYEQTKGQSNPEKLRAVNTTEISEIQQGKVDRFLSNKTEKDEDAAAIKQQEARRMARMAYMQRMER
What are the official names of this protein?
Uncharacterized protein pXO2-81/BXB0111/GBAA_pXO2_0111.
Protein: ATPB_BACTN
Sequence: MSQIIGHISQVIGPVVDVYFEGTDAELMLPSIHDALEIKRPNGKILVVEVQQHIGENTVRTVAMDSTDGLQRGMKVYPTGGPITMPIGEQIKGRLMNVVGDSIDGMKSLDRTGAYSIHRDPPKFEDLTTVQEVLFTGIKVIDLLEPYAKGGKIGLFGGAGVGKTVLIQELINNIAKKHNGFSVFAGVGERTREGNDLLREMIESGVIRYGEAFKESMEKGDWDLSKVDYNELEKSQVSLIFGQMNEPPGARASVALSGLTVAESFRDAGKEGEKRDILFFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTRKGSITSVQAVYVPADDLTDPAPATTFSHLDATTVLDRKITELGIYPAVDPLASTSRILDPHIVGQEHYDVAQRVKQILQRNKELQDIISILGMEELSEEDKLVVNRARRVQRFLSQPFAVAEQFTGVPGVMVGIEDTIKGFRMILDGEVDNLPEQAFLNVGTIEEAIEKGKKLLEQAKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRMB_THEVB
Sequence: MSDRAMVVRVRQHVNPLSQKFQQDIPVPDWSRIYEQPSQPLHLDIGCARGTFLLEMAALYPEQNFLGLEIRYPLVVAANERRDRQQLRNLHYLWGNANVHLSKILGGLPLHTVTIQFPDPWFKRRHHKRRVVTPELVATLAELLPAGGRVVLQSDVFEVAESMVQQFRAHGAFRSTCTDWLPQSPWPVATEREKCVLNKGLAVYRWQFERCAV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SUCP_BIFAA
Sequence: MKNKVQLITYADRLGDGTIKSMTDILRTRFDGVYDGVHILPFFTPFDGADAGFDPIDHTKVDERLGSWDDVAELSKTHNIMVDAIVNHMSWESKQFQDVLAKGEESEYYPMFLTMSSVFPNGATEEDLAGIYRPRPGLPFTHYKFAGKTRLVWVSFTPQQVDIDTDSDKGWEYLMSIFDQMAASHVSYIRLDAVGYGAKEAGTSCFMTPKTFKLISRLREEGVKRGLEILIEVHSYYKKQVEIASKVDRVYDFALPPLLLHALSTGHVEPVAHWTDIRPNNAVTVLDTHDGIGVIDIGSDQLDRSLKGLVPDEDVDNLVNTIHANTHGESQAATGAAASNLDLYQVNSTYYSALGCNDQHYIAARAVQFFLPGVPQVYYVGALAGKNDMELLRKTNNGRDINRHYYSTAEIDENLKRPVVKALNALAKFRNELDAFDGTFSYTTDDDTSISFTWRGETSQATLTFEPKRGLGVDNTTPVAMLEWEDSAGDHRSDDLIANPPVVA
What is the function of this protein?
Catalyzes the reversible phosphorolysis of sucrose into alpha-D-glucose 1-phosphate (Glc1P) and D-fructose (PubMed:14740189, PubMed:20691225).  Is involved in sucrose degradation.  Also displays transglucosylation activity in vitro, by transferring the glucosyl moiety of Glc1P to a broad range of monomeric sugars, such as D- and L-arabinose, D- and L-arabitol, and xylitol (PubMed:14740189).
What are the official names of this protein?
Sucrose phosphorylase, SP, SPase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.
Protein: UPK3L_MOUSE
Sequence: MGPHGKQSVLRMPLLLLLTCVQSGTGLESINYAPQLLGATLEGRLTQSTFTLEQPLGQFKNVNLSDPDPIWLVVAHSNAAQNFTAPRKVEDRHAPANFDRNGYYLTLRANRVHYKGGQPDSQLRVLRVGNDNNCSLESQGCNSPLPGAGPYRVKFLAMSAEGPVAETLWSEEIYLQQAQTFREAPGSQGKGTVVIIAFLSILLAILLVVFLVLVISACLSTSGSSPEEQVRMRHYHTHHMGSLRAERSS
What are the official names of this protein?
Uroplakin-3b-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the uroplakin-3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PUR7_ECOBW
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ACCD2_ROSCS
Sequence: MKELIQRSRKSFTVVHPIESDVPDNVWVKCPSCRELIYHKQLAERMKVCRCGYHMRLTAREWLALLDEGSFVEYDAHLRPTDPLGFVSPKEAYADKLRETQRRTGLADVVVSGVGSIEGYRLSIAVCDFNFIGGSMGSVFGEKMARAAERAATLGIPLLTINTSGGARMQEGVIALMQLAKVNMALTRLAAARQPHIAVLVDPCYGGVTASYASVADIIIAEPGANIGFAGRRVIEQTIRQKLPADFQTAEFMLQHGMVDMVTPRSELHGVLAKLLRLYAAEGRSGAYSSEAVAPTLASI
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 2, ACCase subunit beta 2, Acetyl-CoA carboxylase carboxyltransferase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_MYCBP
Sequence: MSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGEVWLRNAHIPEYRHGSWTNHEPRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKVKVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HEXB_PSEO7
Sequence: MKFNRLMALLFGVSSPLYALDQTAVNWLGQNLDVKYTLLDTKPTTCPKAQQKCYYSELSFSVRKENTKANNDFAIFFSQLMPIYHVEGDNFAITHINGDIHKITPAAGFSGFSSAPTTVRFYTKDSQVTRSEVYAKLCCERTRSLKLTPQVIKSTQTQRDNDTGLDCNLNLTPFVTLNQLQTSSKDDTPWMGSEYLYQHQVKPTLDAAIGLIPKPKQLTVLSDKRLNLAAGINLQLSGISADAIAMAQQRLNTLGVKSTKEGLVVNVAVKPNKQSSPHYQLTVAENNISIQGNNSAAAFYALQSLAGLLDINDLRIPMVDIIDTPRYDFRGLHVDVARNFRSKAFILQTIEQMAAYKLNKLHLHLADDEGWRLAIDGLDELTSVGAYRCFDLTETRCLLPQLGAGNDKNAQVNGFYSAEDYIEILRYAKAHHIEVLPSLDMPGHSRAAIIAMEARYKKLMAQGKPEDAQKYRLVETADKTRYSSIQHYNDNTLNVCIANTYTFIDKVLSEVKVLHDRAGVPLNTYHIGADETAVLWLESPACKKLQASVKDFTNFNGYFIERVAKLLDKKGIQVAGWSDGLGDVRAANMPANIQSNGLGDIKRKRAPVAHRFANQGWQVVLSSPDVTYFDFPYQSHPEERGNHWASRAIESKKMFEFMPDNLPAHAEIWKNTNNHAYIANDSDSSLNKGVQFAGLQGHLWSEMLRSDAQAEYMLYPRLLALAERAWHHAEWELPYQAGRIYSQSSGYFTAKLQAQREADWQRFVAILGNSRTT
What are the official names of this protein?
Beta-hexosaminidase B, Beta-GlcNAcase, Beta-N-acetylhexosaminidase, Beta-NAHase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
Protein: NCMAP_RAT
Sequence: MTTATTLGDAVFSLNMTRGEDILYKSSGAIVAAIVVVVVIIVTLVLILLKMYNRRMRTRRELEPKSPKPPVPPALDPNSNGSQQPAAVTSDPADVPVETR
What is the function of this protein?
Plays a role in myelin formation.
What are the official names of this protein?
Noncompact myelin-associated protein, Myelin protein of 11 kDa, MP11.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localized mainly in the Schmidt- Lanterman incisures and paranodes of noncompact peripheral nerve myelin.
Protein: TRHO_CUPPJ
Sequence: MQIVNISAYKFVSLNDIETLRPEMRSRCEDLELKGTILLAPEGINMFLAGPRESIDGFMAWLHADTRFADIAPKESLSDNQPFKRMLVRAKKEIITMKRPLIRPEEGRAPSVRPVDLKRWLDQGHDDEGRPVVMLDTRNDFEVAVGTFDNVVEYNLTKFSEFPDVIEARKAEFEGKTVVSFCTGGIRCEKAAIHMQEVGIGHVYQLEGGILKYFEEVGGDHYRGDCFVFDYRTALNPNLEPAGPKQCFACRAVVTAEEQQSPHYVVGKSCPHCVGRHDQAAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PFDB_METM7
Sequence: MELPANVQNQLMQFQQLQQQLQMIMYQKQQFETQLKEMEKAIEEMEKSGSDEVFKMAGGILIKRNKAEVKEELSERVETLQLRVTTFEKQEEKMQKRYTELQENLQKAMGQGQ
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_METSB
Sequence: MGKEKFQRNKPHCNIGTIGHVDHGKTSLTAAITKVLAETGGATYTAYDQIDKAPEEKARGITISTAHVEYETKKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFMNKVDMVDDAELLELVELEVRELLSKYDFPGDDIPITKGSALCALEGKQPEIGHDAVLALMDTVDAYIPQPERPIDLPFLMPVEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGLKPTVKTVVTGVEMFRKLLDQGQAGDNIGALLRGTKREDVERGQVLCKPGSVKPHTKFKAEAYILTKDEGGRHTPFFTNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNVTMDVELIAPIAMEEKLRFAIREGGRTVGAGVVASITE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.