PharMolix/UniProtQA huggingface dataset:
Protein: GCSPA_BACHK
Sequence: MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQIASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQHLEVVEINHKDGVTDLDVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEVNDALLQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: GREA_SACEN
Sequence: MSETQVTWLTQDAFDRLKSELDELVGNRPVIAAKINEAREEGDLKENGGYHAAREEQGHLESRIRQLQELLRTAKVGDVPTEAGVAKPGSVLTVRYDDEDETEKFLLATREEGAHGDLEVYSPSSPLGQALLDAKEGETREYELPNGGTMKVTLVKAEPFTG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: INHBA_FELCA
Sequence: MPLLWLRGFLLASCWIIVRSSPTPGSEGPGAAPDCPSCALATLPKDVPNSQPEMVEAVKKHILNMLHLKKRPEVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIQLLQKQPQGGVDAGEEAEEMGLMEERNEVLISEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCHETGASLVLLGKKKKKEEEGEGKKKDGGDGGAGADEDKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins (By similarity).
What are the official names of this protein?
Inhibin beta A chain, Activin beta-A chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TLL1_MOUSE
Sequence: MGLQALSPRMLLWLVVSGIVFSRVLWVCAGLDYDYTFDGNEEDKTEPIDYKDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQSPFGKLGHITGGFGDHGMPKKRGALYQLIERIRRIGSGLEQNNTMKGKAPPKLSEQSEKNRVPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSDEESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESSGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKVAGVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKIMVSEGYHVGLTFQAFEIERHDSCAYDHLEVRDGASENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVIAPSQYRISVKFEFFELEGNEVCKYDYVEIWSGPSSESKLHGKFCGADIPEVMTSHFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYTCQCRNGFVLHENKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWVISAIPGHRITLAFNEFEVEQHQECAYDHLEIFDGETEKSPILGRLCGSKIPDPLMATGNEMFIRFISDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQLDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYVEVFDGLSSKAVGLGRFCGSGPPEEIYSIGDVALIHFHTDDTINKKGFYIRYKSIRYPETMHAKN
What is the function of this protein?
Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase.  Required for the embryonic development, especially heart development.  Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
What are the official names of this protein?
Tolloid-like protein 1, mTll.
What are the subcellular locations of this protein?
Secreted.
Protein: NEJ2_FASHE
Sequence: LEDNGRTHWAVLVA
What are the official names of this protein?
Newly excysted juvenile protein 2.
Protein: MENG_GEOSE
Sequence: MRQSKEERVHRVFENISAHYDRMNSVISFRRHLKWRKDVMRRMNVQKGKKALDVCCGTADWTIALAEAVGPEGKVYGLDFSENMLKVGEQKVKARGLHNVKLIHGNAMQLPFPDNSFDYVTIGFGLRNVPDYMTVLKEMHRVTKPGGITVCLETSQPTLFGFRQLYYFYFRFIMPLFGKLLAKSYEEYSWLQESAREFPGRDELAEMFRAAGFVDVEVKPYTFGVAAMHLGYKR
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ZP3_HUMAN
Sequence: MELSYRLFICLLLWGSTELCYPQPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSVVLLGVGLAVVVSLTLTAVILVLTRRCRTASHPVSASE
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP3 is essential for sperm binding and zona matrix formation.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3, Sperm receptor, ZP3A/ZP3B, Zona pellucida glycoprotein 3, Zp-3, Zona pellucida protein C.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPC subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 3]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: SEC11_LACTC
Sequence: MNLRLELTRFLNLCFALASAFMFWKGLSIVTNSHSPIVVVLSGSMEPAFQRGDILFLWNRNELNKVGDVVVYEVDNKEIPIVHRVLREHVDETSGKQLLLTKGDNNAGNDIPLYAKRKIYLHKEKDIVGTVKGYIPQLGYITIWISENKYAKMGLMGLIALSALLSNE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NAPA_YERPY
Sequence: MKLSRRDFMKANAAVAAAAAAGMTIPTVAKAVGETTNAIKWDKAPCRFCGTGCGVLVGTQNGRIVASQGDPDSPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKDGQYDKEGDFTPISWEKAFDIMELKFKNALKEKGPTAVGMFGSGQWTVWEGYAALKLLKGGFRSNNLDPNARHCMASSVVGFMRTFGMDEPMGCYDDIEEADAFVLWGSNMAEMHPVLWSRMTSRRLTNAHVRIAVLSTYEHRSFELADNPIVFTPQTDLVIMNYIANYIIQNNAVDKDFLAQHVNFRRGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDFKTFVAEYTLEKTAKMSGVPEDQLESLAQLYADPKVKLVSYWTMGFNQHTRGVWANNMCYNLHLLTGKISTPGSGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRQIAETTWQLPAGTIPEKVGLHAVAQDRALKDGTLNAYWVMCNNNMQAGPNINEERMPGWRDPRNFIVVSDPYPTISALSADLILPTSMWVEKEGAYGNAERRTQFWRQQVPSPGEAKSDLWQIVEFAKRFNVEEVWPAELVNQKPEYRGKNLYEVLFANDVVSKYPLSEIPDDQLNDEARDFGFYIQKGLFEEYASFGRGHAHDLAPFDVYHQVRGLRWPVVDGKETLWRYREGFDPFVPKGEEVRFYGKPDGKAVIFALPYEPAAESPDQEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARGLHRGDKVKVISRRGEVISLVETRGRNRPPRGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLERVVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: SELO_SYNP6
Sequence: MPSTNPFLTLPYEPAFASLGSEFSDPVEAATFPAHQLRFRNDRLLPILGLDPATVADEHFIEAFGRFQGRSPLLAMRYHGYQFGIYSPDLGDGRGFLYGQVRGRNGWLYDFGTKGSGRTPYSRGGDGKPTLKGGVREVLASEFLQRLGVRTGRCLSLIETGEELWRGDEPSPTRSSVMVRFNRTHIRFGTFERLHYFKRADLVRQLLDHVIATYYSHLLGDPEADAKFYAELTERTADLAAQWMAAGFCHAVLNTDNLSIVGESFDYGPWAFLDRFDPKFTAAYFDHSGRYRYENQPGICQLNLELLQVPLGMVMSAADLEAGIAGFGDRYQATYSRLMLRRLGFEADQLHSAIADDLIITTLQLLLRAPIGYNEFFARLRAQFQPSWRSDLSAILPDWITTDLEALPEAQWQGWRDRYHQLLTHLPESQLPLIQQQLAQANPEISPIRPVVESVWDPIAIDDNWEPLEALLNRWRHDGDGAADGAVVPNAN
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: AMP1_LIPSI
Sequence: EALYNSEDLYEETSDSDD
What is the function of this protein?
May possess antifungal activity against B. cinerea.
What are the official names of this protein?
Putative antimicrobial peptide 1, Ls-AMP1.
Protein: FLID_BACSU
Sequence: MVTRITGLASGMDIDDIVSKLMQTERAPLDKLTQKKQTLEWQRDSYREVNSKIKELQDYMSKNTLTYPSTYQSKTVTSSNESVLTATGSVSAPNSSSTVEVASLATAATYKANNYTGYTQGDYNLAFNVVAPGETTAKTVNISVTSADTIDNVISKLNSSDLGVSAFKDKIWNGTEYVETIAFSSKATGAGGSIQAADSATADFMSGQLGFSLDADNKLTAYKEGTNAKVTINGFEMEKLTNNFTVNGVTYSIKNTTAATGPVTTSVSTDVDGIYNQIKEFVDKYNELVDSLNEKLKEEKYRDYTPLTSEQKEAMSDKEVELWEEKAKSGLLRNDSSISTGTNQMRTDFYTQVNADGKTYQLTEFGITTSSAYQLRGHLEINEEKLKAKIAEDPQGVANLFTSGTNDSNYSDKGIMKRITNTLRSTVKSIEAKAGNSTMGASSYSIGKNLNSISTEITDMQDRLNTIENRYYSKFSAMDSAIQKMNEQASYLSQLLVQ
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: ATPF_MESVI
Sequence: MTDILTNIFTILSRMSLAEGFGFNTDIFETNILNLAVVLGILLTSGREFFVSLLQNRQQNILQSINDADERYKEAAEKLQQAQNEFEQAKLEADQILAQSKKTASEIEVGLMNLIKEDTKKLLDMKQATISFEEEKAISEIRRQVIRLALQRALEQSKSRLNRRLQKRVTRLNIGLLGRLVTPNDV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPA_CUSEX
Sequence: MVTVRADEIRKIIRERIEQYNREVNTLNTGTVLQVGDGIARINGLDEVMAGELVEFEEGTIGIALNLESKNVGVVLMGDGLMIKEGSSVKATGRIAQIPVGEAYLGRVINAQANPIDGRGKISSSAFRLIESSAPGIISRRSIYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTIINQQGQNVICVYVAIGQKASSVAQVVTTLQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYSERHTLIIYDDLSKQAQAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSKLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKKVAGKLKLELAQFAELEAFAQFASDLDKTSQNQLARGQRLRELLKQSQSAPLTVAEQIMTIYTGINGYLDSLQLRQVRKFLLELCTYLKTNKPRFQEIISSTKTFTEEAEDLLKEAIRDQTDRFLVKEQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, plastid, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: AROC_CERS1
Sequence: MSYNTFGHIFRVTTWGESHGPALGATVDGCPPGVAIEAEAIQHWLDRRKPGQNRFTTQRQEPDAVRILSGTFEGRSTGTPIQLMIENTDQRSKDYGEIARSFRPGHADIAYHWKYGLRDYRGGGRSSARETAARVAAGGVARAALAALVPGLRIEGYMVQIGPHAIDRARFDADEIERNPFWCPDSDTAALWADYLDGLRKAHDSVGAIVEVRASGVPAGLGAPIYGKLDSDLAAAMMTINAVKGVEIGEGMAAACLTGSANADEIRMGPEGPEFLTNHAGGILGGISTGQDVVVRFAVKPTSSILTPRRSVTTDGCEVEVVTKGRHDPCVGIRAVPVGEAMMACVLLDHLLLDRGQTGGLRGTIG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SYR_HELPY
Sequence: MHTLIKGILEEILEEEVIVEYPKDREHGHYATPIAFNLAKVFKKSPLAIAEELALKISTHEKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQVKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLLKENEETIIEVLSGYARDLMLLEIKDNLDALGIHFDSYASEKEVFKHKDAVFEQLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQDYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVVDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTNLNAEEKYLLFSALSLPKAIESSFEEYGLQKMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLIVSLSLSNAFKLLGIEIKTKISARD
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_THEPX
Sequence: MGYRKLGRPSDQRRAMLRNLVTDFLKYGRITTTEARAKEVRSISEKMITLGKRGDLHARRQALAYILDESVVKKLFDEIAPKYKDRQGGYTRILKLGPRRGDGAPLVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y2690_SHEPC
Sequence: MSAVVQQQGDLLLNVYIQPKASRDQIVGLHGDELKVAITAPPIDGKANAHLSKYLAKAFKVPKSDVYIIKGELGRHKQIRIVTPKLIPPEVSELLE
What are the official names of this protein?
UPF0235 protein Sputcn32_2690.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: YHB7_YEAST
Sequence: MDRTWLLLTWLLLLCGVVQGNQESINQKYHDVCSGMYSKEDFNGKVDPYISFTLEELSLADEDDDGEGVSVAVFDFQDYEHIGVRLPNGEIQYICDDYALDLGLCEDSSEGQFIIQETAIDPFTSKEHKLTSQILTFTQQELGTNDKVYSINKTGYYCVTTSSFISSSSKFKATVNFRNAYGQLDASEAYKMPIYAFLAVAYAVCTLVYSWLCWKHRHELLPLQRYILVFCIFLTADTIFVWMYYIIENQKGNSSVALHVYMVFISIFSAGKMTFTLLLALLISLGYGIVYPKLDRTLLRRCQIFAIFTFAVCVAFLVQKYSQNSESLSNLILITAIPLVLCLFAFYYLTLSSMNKTMTYLREQNQVVKLNMYRKLIILCYISLFILFLGLLVSTFAYVGMDTVDMIEQYWKTEFLITDTWPSFVYFLVFVIFAFFWRPTSTSYLLACSHQLPTDMENVSEFDLDDINSLSDEALPNREPRNDYQEHDHNMDIDLASDFEEVPSVNANTNANNDVLFDVDYDRDAKNDRSTT
What are the official names of this protein?
Uncharacterized membrane protein YHL071W.
What is the protein family that this protein belongs to?
Belongs to the LU7TM family.
Protein: UVRB_HALMA
Sequence: MSDTGGPLSIDRPDVDREFRVDAPFDPAGDQPEAIEQLASGYRQGMDRQTLLGVTGSGKTNTVSWVVEEIQQPTLVIAHNKTLAAQLYEEFRELFPDNAVEYFVSYYDYYQPEAYVEQTDTFIDKDASINDEIDRLRHSATRSLLTRDDVIVVASVSAIYGLGDPRNYIDMSLSLEVGQEIERDELLGQLVDLNYERNDVDFTQGTFRVRGDTLEIYPMYARYALRVEFWGDEIDRMLKVDPLEGEVKSEEPAALLHPAEHYSIPEQRLQRAIDEIEKLLDQRISYFERQGNHVAAQRIEERTTFDIEMMQETGYCSGIENYSVHLSDRETGEAPYTLLDYFPDDFLTVVDESHQTLPQIRGQFEGDKSRKESLVENGFRLPTAFDNRPLTFEEFEEKTDQTLYVSATPGDYERDHSDQVVEQIVRPTHLVDPAVEIASATGQVEDLLERIDDRVDRDERVLVTTLTKRMAEDLTEYLEESGVNVAYMHDETDTLERHELIRSLRLGDIDVLVGINLLREGLDIPEVSLVAILDADQEGFLRSETTLVQTMGRAARNVNGEVVLYADERSNAMQSAIQETQRRRRIQQQYNEDHGFEPTTIEKEVGETNLPGSKTETGGISSDGASDADEATRQIEQLEERMQEAADNLEFELAADIRDRIRELREEFDLDGGDDSDGVPAPGPEF
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1668_PELTS
Sequence: MSTNFFFAFESSEMILITLLFLGLFGRSNLVVSSSCILLCLKYFKLDQLVFPVLESRGLELGLVLLMLHILSPVATEKLTIKDLHSVTSLKGLFALAAGTLATKLNGDGLALMNARPEIIFGLTVGTVLGILFLRGTPCGPVMAAAVTAVFLQIASLFS
What are the official names of this protein?
UPF0756 membrane protein PTH_1668.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CBID_CLOTE
Sequence: MLDMYVMVDGKKLRCGYTTGSCATAAAKAATIMLYNKEKLKTIDIDTPKGVRLHLDIEKINIGENYVECCIIKDGGDDPDATHGMEIWARAEKKDDGYTLKGGKGVGVVMGEGLYVAKGEPAINPVPRTMIESEVKSVLPKDRGVEITIFAPEGKKVAKKTFNPRLNIIGGISILGTSGIVMPMSEESLKQSVELEIRQKIANGHKDLILVFGNIGERKGMEMGLDQSKMVSISNYVGFALDCCRGNGVKDITLVGHIGKMCKIAAGCFNTHSRVADVRLEVLALELALMGYDIDLVKDVYNQKTTEGAVKFLGEGYDELYKRIAEKIAKRIEIYSYGEISPKILMFSMEKILFSE
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: RL29_ECO81
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SSRP_RICM5
Sequence: MTEYKKVIAQNKKALFNYFIEERLEAGIVLKGSEVQSLRQGKASIEESHATDTGHEVFLYNCHIAEYEKANRFNHATRRPRKLLLHTKEIKKIIGRIRIKGYTLVALSMYFNKKNKVKVELGIAKGKKLHDKRESIQEKDWKRDQSRLIRQK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RS10_CHLFF
Sequence: MKQQKQKIRIRLKGFDQGQLDRSTADIVETAKRTGARVAGPIPLPTKREVYTVLRSPHVDKKSREQFEIRTHKRLIDILDPTGKTIDALKMLALPAGVDIKIKAA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TSAD_ARTS2
Sequence: MNRTQPLVLGIESSCDETGVGIVRGTALLSNTVSSSMEEHVRFGGVIPEIASRAHLDAFVPTLQEALADAGVQLDDVDAIAVTSGPGLAGALMVGVCAAKALAVATGKPLYAINHLVAHVGVGLLQEENTLPEHLGALLVSGGHTEILRIRSITDDVELLGSTIDDAAGEAYDKVARLLGLGYPGGPAIDKLARTGNAKAIRFPRGLTQPKYMGTADEPGPHRYDWSFSGLKTAVARCVEQFEARGDEVPVADIAAAFQEAVVDVITSKAVLACTENGITELLLGGGVAANSRLRQLTEQRCRAAGIRLTVPPLELCTDNGAMVAALGAQLVMAGIEPSGISFAPDSSMPVTTVSA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM2_MOUSE
Sequence: MLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQ
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm2, Protein G7b, snRNP core Sm-like protein Sm-x5.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: IL4_MERUN
Sequence: MGLSPQLAAVLLCLLVCTGNYARRQDREAGLREIIHNLDQVLKKETPCTEMFVPDVLIATKNTTEKGLLCRATRVLRKFYFPREVTPCLKNNSGVLSILRKLCRSISTLHPQESCSVSTPTLTTLNDFLGRLRGIMQMKNWQG
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.