PharMolix/UniProtQA huggingface dataset:
Protein: FUN30_YEAST
Sequence: MSGSHSNDEDDVVQVPETSSPTKVASSSPLKPTSPTVPDASVASLRSRFTFKPSDPSEGAHTSKPLPSGSPEVALVNLAREFPDFSQTLVQAVFKSNSFNLQSARERLTRLRQQRQNWTWNKNASPKKSETPPPVKKSLPLANTGRLSSIHGNINNKSSKITVAKQKTSIFDRYSNVINQKQYTFELPTNLNIDSEALSKLPVNYNKKRRLVRADQHPIGKSYESSATQLGSAREKLLANRKYGRHANDNDEEEEESMMTDDDDASGDDYTESTPQINLDEQVLQFINDSDIVDLSDLSDTTMHKAQLIASHRPYSSLNAFVNTNFNDKDTEENASNKRKRRAAASANESERLLDKITQSIRGYNAIESVIKKCSSYGDLVTSQMKKWGVQVEGDNSELDLMNLGEDDDDDNDDGNNDNNNSNNNNTAGADATSKEKEDTKAVVEGFDETSAEPTPAPAPAPVERETKRIRNTTKPKVVEDEDDDVDLEAIDDELPQSEHEDDDYEEEDEDYNDEEEDVEYDDGDDDDDDDDEFVATRKNTHVISTTSRNGRKPIVKFFKGKPRLLSPEISLKDYQQTGINWLNLLYQNKMSCILADDMGLGKTCQVISFFAYLKQINEPGPHLVVVPSSTLENWLREFQKFAPALKIEPYYGSLQEREELRDILERNAGKYDVIVTTYNLAAGNKYDVSFLKNRNFNVVVYDEGHMLKNSTSERFAKLMKIRANFRLLLTGTPLQNNLKELMSLLEFIMPNLFISKKESFDAIFKQRAKTTDDNKNHNPLLAQEAITRAKTMMKPFILRRRKDQVLKHLPPKHTHIQYCELNAIQKKIYDKEIQIVLEHKRMIKDGELPKDAKEKSKLQSSSSKNLIMALRKASLHPLLFRNIYNDKIITKMSDAILDEPAYAENGNKEYIKEDMSYMTDFELHKLCCNFPNTLSKYQLHNDEWMQSGKIDALKKLLKTIIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLIDKFYEDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIEEKIHQLAKNKLALDSYISEDKKSQDVLESKVSDMLEDIIYDENSKPKGTKE
What is the function of this protein?
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization.  Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs, facilitating single-stranded DNA (ssDNA) production by the EXO1 and SGS1 machinery.  Promotes gene silencing at heterochromatin by regulating the chromatin structure within or around silent loci.  Also required for heterochromatin organization at centromeres.
What are the official names of this protein?
ATP-dependent helicase FUN30.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Recruited to double- strand breaks (DSBs) sites of DNA damage.
Protein: HSLV_IDILO
Sequence: MTTIVSVRRGDKVVIGGDGQVSLGNTVMKGNARKVRRLYHDKVLAGFAGGTADAFTLFERFESKLEQHQGNLMRAAVELAKDWRTDRALRRLEALLAVADKETSLIITGNGDVVQPENDLIAIGSGGPFAQSAARALLENTDLNARDIVQKALTIAGDICVYTNGNQTIEEEESIAEDKTKQGKK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBP_XENTR
Sequence: MDQNNSIPPFQGLASPQGSLTPGINIFSPLMPYGTGLTPQPVQTTNSLSILEEQQRQQQQAQQSTSQQGNQGSGQTPQLFHPQTLTTAPLPGNTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.  Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis (By similarity).  Binds to the promoters of select genes.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DYR_DROME
Sequence: MLRFNLIVAVCENFGIGIRGDLPWRIKSELKYFSRTTKRTSDPTKQNAVVMGRKTYFGVPESKRPLPDRLNIVLSTTLQESDLPKGVLLCPNLETAMKILEEQNEVENIWIVGGSGVYEEAMASPRCHRLYITKIMQKFDCDTFFPAIPDSFREVAPDSDMPLGVQEENGIKFEYKILEKHS
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: PUM_DROME
Sequence: MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNSGNAGILSPRDSTCAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKANSPFDTNGLKKDDQVTNSNGVVNGIDDDKGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQQNFDVQQLFRSQNPGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAENQPYQVIPAFLDHTGSLLMGGPRTGTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL
What is the function of this protein?
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets.  Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) (PubMed:1459455, PubMed:1576962, PubMed:9404893, PubMed:9660969, PubMed:22345517).  Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of deadenylase complexes leading to translational inhibition and mRNA degradation (By similarity).  Also mediates deadenylation-independent repression by promoting accessibility of miRNAs (PubMed:22345517).  Mediates post-transcriptional silencing of E2f mRNA by binding to its 3'-UTR and promoting miRNA regulation (PubMed:22345517).  Required for abdominal development and to support proliferation and self-renewal of germ cells.  Pum is the only gene required for nos activity that is not also required for posterior localization of germline determinants.  Pum is required during embryogenesis when nos activity apparently moves anteriorly from the posterior pole (PubMed:1459455, PubMed:1576962, PubMed:9404893, PubMed:9660969).
What are the official names of this protein?
Maternal protein pumilio.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=It is concentrated in the cortical region of the embryo beneath the nuclei.
Protein: TRUD_PYRAB
Sequence: MLEELKYLSETPGIGGRIKVKPEDFIVREIIPKSIFKGNCQIYLMKKRNWETIAAIKEIAKRIGIHYSEIGFAGTKDRHAVTYQYISVCRDVRKEVEKLKIRDVELKFVGYGRPLKLGFLLGNFFLIRVRDVKRPELIPKIIEELKIKGGFPNYFGIQRFGEKRSVNHIVGKLLLEGKYEEAAEVFLGYPGNGMEGDEARKRFLETKDVDLALEEFPKFLRYERAMLYRYRETRSWKKAFLVLPRPILRIFIHAFQAYLFNLYLSRRIEEGLPLNEAIPGDIVVQVKRGIPLRTRTYRVTETNVDFVNEKIKRGEAMVSGPIFGYSYRKAHGIPGRLEEEILDENEVNVEMFKKLPKPMREPGGRRELLIKPRKFAYKRKEEEVLFKFFLPKGVYATSVLREITKH
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: PYRB_LEPBP
Sequence: MYAYSHKNILDTLQFSKDDLNYLITKTNRMNALHESGKAFGILHGKLLASLFFEASTRTRMSFEAAMERLGGRLISTVGFQFSSISKGETLYDTMKMIEAYCDIAVIRHPVEGSSRIAAGAVNIPVINAGDGAGQHPTQALLDLYTIVSEKGKIDGLNIAFIGDLKYGRTIHSLINLLRHYPVHLYLISPEELRLPEKYKKNLEGFPMTWEETTDIKAIWDADVAYVTRIQEERFPDHREYEKLKDIYKVNKELVLASKKDTTILHPLPRVNELSTDVDDLPNAAYFRQAKYGVVVRMALLCLSLGVNFD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL31B_PORGI
Sequence: MKKGIHPENYRPVVFKDMSNEDIFITRSTMEAKETIEIDGVTYPLIKVEISNTSHPFFTGKAKLVDTAGRVDKFMSRYGDRNKKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RL22_SALNS
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RS15_AERS4
Sequence: MSLNAEIKASIVADNARCANDTGSPEVQVALLTAQINHLQGHFKEHAKDHHGRRGLLRMVSQRRKLLDYLKRKDVQRYAALIAKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RIMI_ECOL6
Sequence: MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQLTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM
What is the function of this protein?
Acetylates the N-terminal alanine of ribosomal protein S18.
What are the official names of this protein?
[Ribosomal protein S18]-alanine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. RimI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_CHLTA
Sequence: MQTIYTKITDIKGNLITVEAEGASLGELVQIERADGRSSYASVLRFDARKVTLQVFGGTSGLSTGDKVIFLGRPMEVIYGDSLLGRRFNGTGKPIDREDECFGEPIPITTPSFNPVCRIVPREMVRTNIPMIDMFNCLVKSQKIPIFSSSGENHNALLMRIAAQTDADIVIIGGMGLTFVDYNFFVKESQRLGFADKCVMFIHKAVDAPVECVLIPDMALACAERFALEQKKNVLVLLTDMTAFADALKEMAITMDQIPANRGYPGSLYSDLAVRYEKAVDIAQGGSITLISVTTMPGDDITHPVPDNTGFITEGQFYLKDNRIDPFGSLSRLKQLVIGKKTREDHGDLANALIRLYADSRKSAERMSMGFKLSNWDKKLLAFSELFEARLMSLEVNIPLEEALDIGWKILYQSFHSEEVGIKEQLIQKYWPKACLHK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: KDUI_SALDC
Sequence: MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDRIIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFHMMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: KDSA_BORBR
Sequence: MMKACGFDIGLDHPFFLIAGPCVIESRELAFETAGRLKEITGKLGVSFIYKSSFDKANRSSGKSFRGPGMDEGLKILADVRAQLDVPVLTDVHDIDQVAPVAAVVDMLQTPAFLCRQTDFIRACAATLKPVNIKKGQFLAPHDMLQVARKARDAALEAGGDGNNILVCERGASFGYNNLVSDMRSLAIMRETDCPVVFDATHSVQLPGGQGASSGGQREFVPVLARAAVAVGVAGLFMETHPNPACAMSDGPNAVPLDRMAELLESLVALDRVTKRSGFLENQFV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRPBB_ARATH
Sequence: MNAPERYERFVVPEGTKKVSYDRDTKIINAASFTVEREDHTIGNIVRMQLHRDENVLFAGYQLPHPLKYKIIVRIHTTSQSSPMQAYNQAINDLDKELDYLKNQFEAEVAKFSNQF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  NRPB11 is part of the core element with the central large cleft.  Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.
What are the official names of this protein?
DNA-directed RNA polymerases II, IV and V subunit 11, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II subunit J, DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPH_MAIZE
Sequence: MNPLIAAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GATB_OSTTA
Sequence: MSLASVAARRASSLRASTLVRTTFNRAIASASAGDALETVVGVEIHVRLQTRSKLFSGSASAYGGEPNSRVAPFDASLPGTLPVLNAGAVALAVKLGIALEGEVQLRSAFDRKHYWYADLPHGYQITQKRSPIVLGGVVRCQGNLSGDDAGDERSTDGALKVGIERVQLEMDTGKSSVAEDGRGTLVDLNRAGQALVEIVSEPDMRSGEEAVACVEALQRMLRYLHVSDANMEEGSLRCDVNVSVRTSEERARGVFGERVEIKNLNSLRSIARAVKYEAQRHAKVLAGGGKIERETRSFDVNTGKTVVLRTKENLLDYKFTPEPDLPSLVLTSADVEAIAGRMPELPNAAYERLVSGGASPSASNTIVAFPSTLKYFDVAMENCGAAKSADVANFIANEIIGAARKDAGATHKEPLSTLPRAASARRVGELLGKVADGTLSGRMAKQVLEALMNSDERALGDIVDDICGGGQISSDDHLRDICHSVVRDKPEEVRLLQGGKSKLMGALVGEVMKRTSGRANPKDVSKLLADIVAGEP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: REC8_MOUSE
Sequence: MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLNVNVVKTCEEILNYVLVRVQPPVAGLPRPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRAQLRIRIDMEEADLPSLLLPNCLAMMETLEDAPEPFFGKMSVDPRLPSPFDIPQIRHLLEAATPEKTRKETLPEATPDPRKPDRTLATVQSPEVITLQEAEPIRMLQIEGEQDLPEISRGDLELLIAEKDDAILLEERQRGRLLRQRRASLPLDESREEPRALEGAGLVSALSPPAPAQVEGIQEALPGQVFPPEVQKMTGWEPGALLTEVTPPQELRLPAPPSTEKRLPSLQRPLPRRHRRRQLLFWDKETQISREKFEEQLQTGAHCWEYPVAQPPKRMLTSPAELFRTPTLSGWLPPELLGLWTHCAQVPQRMLRQRPQLETEETVEEERAADEEERRKTEALSEIEVLREAQEPSGPLMLSSELSLEAAEDEKSRTSLIPPEWWAWSEEGQPEPPALPMLPELPEVPMEMPPRPELSSEAVLRAVALKLQANKELDFSSLVPPLSPRKLASRVFYLLLVLSTQKILLVEQQKPYGPLLIRPGPKFP
What is the function of this protein?
Required during meiosis for separation of sister chromatids and homologous chromosomes.  Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.
What are the official names of this protein?
Meiotic recombination protein REC8 homolog, Cohesin Rec8p.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=In meiotic chromosomes, localized along axial elements in prophase from the leptotene to diplotene stages. At later prophase stages, diakinesis and metaphase I, localized along interstitial axes of chromosomes including both centromere and arm regions. No longer detected in arm regions in anaphase I but persists on centromere regions until metaphase II.
Protein: RS8_DESVM
Sequence: MLTDPIADMLTRIRNAHLALHKEVSVPRSKIKESIAAILKQEGYIEDVATEEAEIKISLKYFKGKPVISGLKRVSKPGRRVYVGSTDIPKVQNGLGICILSTSSGVLAGTQARDRKVGGELLCEIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TRMD_GLUOX
Sequence: MSWRADILTLFPNMFPGPLGFSLAGRALERGIWSCEAHDLRQHGLGRHRAVDDTPFGGGAGMVMRADVLDTALSALPALDGRPVVYPTPRGRRISHEDAERLSSGPGVVVLCGRFEGVDERVLEKHDIEQLCMGDVVLSGGEIPALTLLDACVRLLPGVMGSDVSGQDESFADGLLEYPQYTKPAVWDGRDVPDILLSGNHGAIARWRHEQSIAVTKARRPDLWDAYLARQQVH
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_YERP3
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METC_ECOLI
Sequence: MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV
What is the function of this protein?
Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis (PubMed:7049234).  Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine (PubMed:12883870).  In addition, under certain growth conditions, exhibits significant alanine racemase coactivity (PubMed:21193606).
What are the official names of this protein?
Cystathionine beta-lyase MetC, CBL, CL, Beta-cystathionase MetC, Cysteine desulfhydrase MetC, CD, Cysteine lyase MetC, Cysteine-S-conjugate beta-lyase MetC.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_ECO27
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASSY_RHOPA
Sequence: MTTILKSLPKGENVGIAFSGGLDTSAALLWMKQKGAKVFAYTANLGQPDEADYDAIPRKAMEFGAEKARLVDCRTQLVHEGIAAIQAGAFHVSTGGIAYFNTTPLGRAVTGTMLVSAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNPALRIYKPWLDQQFIDELGGRAEMSAFMTSHGFAYKMSAEKAYSTDSNLLGATHEAKDLEHLDSGIKIVNPIMGVPFWRDDCAVKAEAVTVRFEEGQPVALNGQTFTDPVAMFYEANAIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLVTGIHNEDTIEQYRINGMKLGRLLYQGRWFDSQALMLRETAQRWVARAVTGEVTLELRRGNDYSILNTVSPNLTYAPERLSMEKVEDAPFTPADRIGQLTMRNLDITDTRAKLGLYAKTGLLSSGEGTPIPQLENDKG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HASR_XENLA
Sequence: MENTTDPENIPVSKPKYPTIRRILSQTFRILLLFSITTAYVLGYQALCHQGLLITFGLYGAAMLLHLLMQGIFANLEIRRIEKRDGVCSFKKTVALTITGYQENPDYLRQCLESCKGMKYPKDKLKIILVIDGNNEEDVYMMEIFKEVFHGEDVGTYVWQENYHTWNIPSEESEDSSSEISSFPWKNEGIQMVEELVRTKRCVCIMQQWGGKREVMYTAFRALGTSVDFILVCNSDIKLDKMATVELVKVLEDDDKNGAVGGDVRVWNRHDSFISFMSSLRYWMVFNMEIACQSYFDSVTYIRGSLGMYRNDILQAFLEFWYNKTFLGTRCPIGDDRFLTNRVLSMGYRTKYSHKSCAYAPCQYLRWLNQQTPWARSYFRMWFCNAQWWHQHHIWMTYESATGIFFPFFVTAVLIRLMYSSSLCNIVWLFLCIQIMSLLLSLYASWQSKKLSMVLMSLYSTLYIIWLLPCQLVALLTIAKSDWGTSGRKKVVNNYVPLFSLSIWAAVLLGGLCYSMYIGCRKDWSKPQANRELYHLLYGCAGYMAYWVLMTVIYCVSGSCCKMRSQAVPQTHDITSLSVSLLV
What are the official names of this protein?
Hyaluronan synthase-related protein, Hyaluronan synthase-related sequence, xHAS-rs.
What is the protein family that this protein belongs to?
Belongs to the NodC/HAS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.