PharMolix/UniProtQA huggingface dataset:
Protein: CLMP1_CRYNB
Sequence: MATYLAPPVSSNKENSPAPNIALSDIDAISLSLRTSLSGVTLPAKKKVAALGLGRAPKFTYRRHSNKPYNRSTSITRAKKAAVQTKSVRSKAAVKKSNTRPLPLKLVQRLDVESARLERLRKAVWNPPAPVPGQVRVPLKLPYPRFPSIEYIDNEYLKEIPVQYIFDRMVPLLPSIATITLAYQPYASIPHPDSKILRDTTLAFAIPEVIDGRKPHWAAKARGREPDLALAVAYKSGEGSNGNTVVAVNSLAFATQCAYWPRLLTTSIPIPTPKRPTPSASAVSTSLPAIVETEENVSDASFSSSSSWSDSDSEVEFIDLPRLPRPVKDDKGFLHLPLVELPIPSPSTFPIIHRHLHHPSRALLPDLLGLPEHYTTRSQVLDAISGLSVQQLMDKLTTLQGVWQNLCSLGIGRLGTWRQLGEAWACVVGVIAGQGLLIAGQEEAEVQRTGRKTAAEDVAWEWVRREKAKEQQ
What is the function of this protein?
Required for developmental progression after cells of opposite mating types fuse with one another, essential for processes common to both dikaryotic filament formation and monokaryotic fruiting.  A direct target for transcription factors Sxi1-alpha and Sxi2-a.
What are the official names of this protein?
Clampless protein 1, CLP1.
Protein: MASP2_PARVS
Sequence: INWLKLGKMVIDAL
What is the function of this protein?
Antimicrobial peptide (PubMed:28108242, PubMed:30974767).  Is active against both Gram-negative and Gram-positive bacteria (Staphylococcus aureus (MIC=2 uM), Mycobacterium abscessus subsp.  massiliense, and S. aureus (EC(50)=1. 83 uM), Escherichia coli (MIC=5 uM), Pseudomonas aeruginosa (MIC=38 uM), Bacillus cereus (MIC=5 uM), and the multidrug-resistant bacterium A. baumannii), and fungi (Candida albicans (EC(50)=12. 9 uM, EC(90)=15. 3 uM) and Cryptococcus neoformans (EC(50)=11 uM, EC(90)=22. 7 uM)) (PubMed:28108242, PubMed:30974767).  Inhibits biofilm formation of A. baumannii and Staphylococcus spp.  bacteria (PubMed:30974767).  Mycobacteria cell shape and cell wall integrity are not altered after exposure to the peptide (6. 25 uM) (PubMed:28108242, PubMed:30974767).  Has low hemolytic activity (MIC=50 uM) (PubMed:28108242) (By similarity).  Is also cytotoxic to mouse peritoneal macrophages (EC(50)=13. 19 uM) (PubMed:28108242).  Also causes moderate mast cell degranulation (ED(50)=80 uM) and exhibits chemotactic activity for polymorphonucleated leukocytes (PMNL) (By similarity).  In vivo, shows antistaphylococcal activity (S. aureus) with a decline bacterial load after 6 days of topical treatment (PubMed:28108242).
What are the official names of this protein?
Polybia-MPII.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha- helical membrane channel in the prey.
Protein: LIAS_ARATH
Sequence: MHSRSALLYRFLRPASRCFSSSSAVTPVTVTQSPKSLEALRARLANESPSLTDFIHGDTYSVEVGTKKKPLPKPKWMKESIPGGERYVQIKKKLRDLKLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAETVQRLKFLKPEMLIEALVPDFRGDGGCVEKVSKSGLDVLAHNIETVEELQSFVRDHRANFKQSLDVLRMAKEYAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPDAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMIEADRVASPSTSP
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (PubMed:9808738, PubMed:24872381) (By similarity).  Together with LIP2 is essential for mitochondrial protein lipoylation during seed development.  Required for the lipoylation of mitochondrial pyruvate dehydrogenase component E2 proteins in leaves and roots (PubMed:24872381).
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoate-protein ligase, AtLPLA, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIFE1_HAEIF
Sequence: MKTLTTYAKYFTPISKIAFLFCFLMGNIAEATIKRAKFTNGFSGINRIITYTFEGSSTMIASATTPEQILFSKARDNTVIDPSYSNNVQQWSVFNNWIDTTVSGDTGYSFAGFSCVSNPCAQMQLPLRFYLDSAILEATSMRSADNQVIFKIRQHPELGVSFQLGMKKGIEDVKWLSNLQQEDFLLTTLQIYFGDAADISFKVRAKLHLLKLPTENTELPTMKLNLGQIKLQSWGINNWGRTKVSYRVQDVGSLNVQLKTPKIYFIQQQRQCILNSTYKKIPVTLKSVKKREFETNTEIEGGQFKLRVNCEDTTYNKFNGKWLFPVVKVTFRGEDGTMNDGTNELLRTQTGTGQATGVSLKIKRDSGNGDSVKYGLDSANMNNHGQFELKKQPSPAGGDQSAEETFKVYYVKDTTRGALTEGKVKAAATFTMSYQ
What is the function of this protein?
May be a minor structural protein required for pilus biogenesis.  May be the adhesive component in the pili.
What are the official names of this protein?
Minor fimbrial subunit HifE.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: Y1798_STRP3
Sequence: MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK
What are the official names of this protein?
UPF0297 protein SpyM3_1798.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: RL4_VIBVY
Sequence: MELMVKGAAALTVSEATFGREFNEALVHQVVVAYAAGARQGTRAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPLWRTGGVTFAAKPQDHSQKVNKKMYRGAMKSILSELVRQERLIVVDNFSVEAPKTKELVAKLKELELNDVLIVTGEVDENLFLAARNLYKVDARDVAGIDPVSLIAFNKVLMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: BHMT2_PONAB
Sequence: MAPAGHPGAKRGILERLESGEVVIGDGSFLITLEKRGYVKAGLWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSASEDNMESKWEDVNAAACDLAREVAGKGDALVAGGICQTSIYKYHKDEARIKKLFRQQLEVFAWKNVDFLIAEYFEHVEEAVWAVEVLKESDRPVAVTMCISPEGDMHDITPGECAVRLVKAGASIVGVNCRFGPETSLKTIELMKEGLQRAGLKAHLMVQPLGFHTPDCGKEGFVDLPEYPFGLESRAATRWDIQKYAREAYNQGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSALDMHTKPWVRARARREYWENLLPASGRPFCPSLSKPDV
What is the function of this protein?
Involved in the regulation of homocysteine metabolism.  Converts betaine and homocysteine to dimethylglycine and methionine, respectively.  This reaction is also required for the irreversible oxidation of choline (By similarity).
What are the official names of this protein?
S-methylmethionine--homocysteine S-methyltransferase BHMT2, SMM-hcy methyltransferase, Betaine--homocysteine S-methyltransferase 2.
Protein: TEG5_EHV4
Sequence: MDQHHGVRGGAPIRRPRRSIETRSHPFRAAGNTQRTYSTPRLSYRDGLSGRASSLEPGGQAHDQNESSTQSTSNNQPSTSFWGYLRRVFSDDAPAQPQAPRSRADFAPPPEEDSSSEEEDEEGPSQAPLDEEDQLMYADQYSVGNSSDDNEEDYLQPEVEYPTSAESGEYHNSGMFAEEEPESESESDMENYETYEENDTEVISDDSHRLTRTWLDRSIRLMDDALAQSSEISKAITKSTRRLYDSQFTPGGRGYKQTETPSQRLVHLSRAGMYDSDEIVMTGDYMEVDDDPNSAYQSWVRAIHHPVAMNPSWEETISNHTNTSFSADIDYDIDELIEMNLARTPPVFEGLLDSADFFYRLPMLYTYATITQDEAYEERQAWSNTQALHGHEQSSWPALVSDYSKGGMYVSPTQEPRGIWRRALKQAMALQLKLCVLGLTEFVTKRELTQHHSAVTFLVDSLLRTAKNCYLASRLLVFAWERRRETGVRRPAEPLIALSGVTLLQPLPPEVSELLEQRTFDIGLRTPQSGVFRAFFGPLVYWAELRRALRDPAAINCRYVGFHLQTSEIYLLARAHSASPGYTKEELVAMEATLTLGTLMLEVALQWIHVASAQLLSENDALKAFRRVSASIPHALAPLGSIRLHDAEFEVLSNPDVMVARDETALSQALFLGYFSVRTALTACMRDYANEVDGGSKETVTGLFLGVGLIIQRLAGHMNFLLNCMAGAALYGGSKIAIHSLTLPRYSLLADVMAPMLQQQSLVDFWRARDDMLEELEITPRPGPPTQGKRVVLEMPLPSDDLPAMTPSGQVNNGAGLGRMVDMAKHLQHYRETIIGDDASSSVGKRGLMKSGVGVRHALEAEKVIRYSPKST
What is the function of this protein?
Tegument protein that can bind to various RNA transcripts.  Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase UL41/VHS.  Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins UL31 and UL34.
What are the official names of this protein?
Tegument protein UL47 homolog, GP10.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL47 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection. Localizes to the major sites of transcription in the infected cell nucleus.
Protein: LEUC_LACLA
Sequence: MSGKTIFDKLWDQHVIAGNEGEPQLLYIDLHVIHEVTSPQAFQGLREAGRRVRRKDLTYGTLDHNVPTQDIFNIQDLISKKQIDTFTKNVKEFDVPAETHGGKGQGIVHMVAPESGRTQPGKTIVCGDSHTATNGAFGAIAFGIGTSEVEHVLATQTIWQVKPKRMKIEFQGHPQKGIYSKDFILALIAKYGVDAGVGYAVEYSGDAISDLSMEERMTICNMSIEFGAKIGLMNPDEKTYDYVKGREHAPKNFDEAVSKWEKLVSDSDAQYDKILSLDVSQLKPMVTWGTNPGMGLEFGEKFPEINNDLNYERAYQYMDLKPGQTASAIDLGYIFIGSCTNARLGDLEEAAKIIGDRHIADGLTGIVVPGSRPVKEAAEAQGLDKIFKEAGFEWREPGCSACLGMNPDQIPEYVHCASTSNRNFEGRQGHNARTHLCSPAMAAAAAIAGKFVDVRTLVTD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TRUA_EXIS2
Sequence: MRRFKCTIQYDGTDYSGYQVQPNGLTIQEVLEKTLGRMHKHPVKVIGSGRTDARVHAQGQVIHFDTELSIAPASMVKALNTLLPDDIRVRDCKEVASDFEARYDVVGKEYRYFVRRTENAFRRHQSVLIPYSLDVAQIRLGLAHLVGTHDFSSFCVAKTETDNRVRTIYEAELIEQGEELIFRFQGSGFLYNQIRIMVGTLLDVGRGRFAPDDIKRMLEAKDRNVAGVTAPPHGLYLWEVFYPESKKGI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: UFM1_DROVI
Sequence: MSKVTFKITLTSDPKLPFKVLSVPEATPFTAVLKFASEEFKVPAETSAIITDDGIGISPQQTAGNVFLKHGSELRLIPRDRVGH
What is the function of this protein?
Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
Protein: UVRA_PARDE
Sequence: KLSKELSRRATGKTLYILDEPTTGLHFEDVRKLLEVLHSLVDQGNTVVVIEHNLDVIKTADWIIDIGPEGGDGGGAIVATGTPEQVAEVPESHTGRYLAPMLDAARSAAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity).
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_BACAN
Sequence: MERQFEIVSAYSPQGDQPVAIEKLVEGINSGKKKQVLLGATGTGKTFTISNVIKEVQKPTLVMAHNKTLAGQLYSELKDFFPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDAQINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGSPEEYRELVVSLRVGMEKDRNQLLRELVDVQYGRNDIDFKRGTFRVRGDVVEIFPASLDEHCIRIEFFGDEIDRIREVNALTGEVLAERDHVAIFPASHFVTREEKMKVAIENIEKELEERLKELNDNGKLLEAQRIEQRTRYDLEMMREMGFCSGIENYSRHLTLRPAGATPYTLLDYFPKDFLIVMDESHVSVPQVRAMYNGDQARKQVLVDHGFRLPSALDNRPLTFDEFEEKTNQVIYVSATPGPYELEQSPEVIEQIIRPTGLLDPPIDIRPIEGQIDDLLGEIQDRIAKNERVLITTLTKKMSEDLTDYLKDVGIKVNYLHSEVKTLERIEIIRDLRLGKFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNENGRVIMYADRITRSMGIAIEETKRRRSIQEAYNEEHGITPKTIQKGVRDVIRATTAAEEPETYEATPAKKMTKKEREKTIAKMEAEMKEAAKALDFERAAELRDLLLELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAEP_SALSV
Sequence: MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALSESVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: SPT16_CANGA
Sequence: MSELNIDAEAFKARVELLHGKYREFENEPNSMVFALGSSNPENPYQKTTALHYWLMGYEFPATLIVFTPGKVVIITSGPKAKHLEKVVELFKNNNNGVELEIWQRNNKDVEHSQKLFKDIIELINTAGKTVGIPEKDVYEGKFMKEWKPIWDAAIKEHEFKLVDISAGLSSTWEVKDDKEKAYISIASKCSDRFMNLLSDEMVRAVDDELKITNSKLSDKIENKIDDLKFLKKITNDLSAMCPPNHKFTLDLLDWTYSPIIQSGNKFDLRVSAHSNNDQLHGNGCILASCGIRYNNYCSNTTRTFLIDPSEEMVNNYVFLLDLQKHIIENELKAGRTGKEVYESVVEFIKKVRPELAGNFTKNIGSLIGLEFRDSFFVLNSKNDKRKIQVGDCFNISFGFNALKDMKTNTNYALQLADTVILNEDGPKILTEYTKSKSQVSFYFNNDEVEKEKKPAASTKIPTNLDGNSKILRSKLRGDARGESQDAQKEQIRKENQRKLHEKLQKEGLLRFTAEDATTEGSETRQYFKKYESYVRESQIPNNVRDLRIHVDWRSQTIIVPIYGRPVPFHINSYKNGSKNEEGEYTYLRLNFHSPGSAGGISKNVVELPYDDSPDNQFMRSITLRSKDGDRMSETFKQITDLKKESTKREQERKALADVVQQDKLIENKTGRTKRLDQIFVRPSPDTKRVPSTVFIHENGIRYQSPLRTDSRIDILFSNIKNLIFQSCKGELIVIIHIHLKNPIMMGKKKIQDVQFYREASDVSVDETGTGRRNQNKFRKYGDEDELEQEQEERRKRAMLDKEFKYFADAIAEASNGLVSVESTFRDLGFQGVPNRSAVFCMPTTDCLVQLIEPPFLVVNLEEIEVAILERVQFGLKNFDLVFVYKDFKKPVTHINTIPIESLDFLKQWLTDMDIPYAISTINLKWSTIMQSLQEDPHQFFLDGGWSFLNANSDEEGSDESEEEISEYEASEEEPEDESAYSDEDDYSEDISDGSYSGADSEEEEGEDWDELEKKAAKADRTAGLRD
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit SPT16, Facilitates chromatin transcription complex subunit SPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CLIC1_BOVIN
Sequence: MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPDEVDETSAEDEGISQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFSIPDVFRGVHRYLRNAYAREEFASTCPDDEEIELAYEQVAKALK
What is the function of this protein?
Can insert into membranes and form chloride ion channels.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions (By similarity).
What are the official names of this protein?
Chloride intracellular channel protein 1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Protein: UBAC2_MOUSE
Sequence: MFTSTGSSGLYKAPLSKSLLLVPSALSLLLTLLLPHCQKFFVYDLHAVKHDLQIWRLICGRIICLDLKDAFCSGLLIYNFRIFERRYGSRKFASFLLGSWVLSALFDFILVEAVQYSLGVTVASNLPSGFLAPVFALFVPFHCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAMSGLISGMCYDRKVLQVHQVLRIPGRMAEFFSWALEPIFSSSEPTSEARVGMGATVDIQRQQRMEQLDRQLMLSQFAQVRRQRQQQGGMINWNRLFPPLRQRRNINYQDGPRSEQRASPPLEVSEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH
What is the function of this protein?
Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (By similarity).  In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (PubMed:31073040).
What are the official names of this protein?
Ubiquitin-associated domain-containing protein 2, UBA domain-containing protein 2, Phosphoglycerate dehydrogenase-like protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GMHBB_RHOPA
Sequence: MTASAPRRPAAFLDRDGVINYNDHYVGTRERLRWMPGIAAAIRQLNAAGYYVFIITNQSGVARGMFSEDDVRALHRWMLDELNTQGARIDDVRFCPHHVEGTLDAYRVACEHRKPGPGMILDLAKTWPVDMTRSFVIGDSASDVEAAKAAGIPGFRFEGEDIDVFVKQVLIEMQRAAVSN
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.  Also catalyzes the dephosphorylation of D-glycero-alpha-D-manno-heptose 1,7-bisphosphate in vitro.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the gmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOIH1_CANPG
Sequence: RRINNDCQNFIGNRAMYEKVDWICKDCANIFRKDGLLNNCRSNCFYNTEFLWCIDATENTRNKEQLEQWAAILGAGWN
What is the function of this protein?
Represses the synthesis of methyl farnesoate, the precursor of insect juvenile hormone III in the mandibular organ.
What are the official names of this protein?
Mandibular organ-inhibiting hormone 1, MOIH-1.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDVA_BARBA
Sequence: MSLFRTYVRVLSYLNQEKNAFLLICTANITLAIITIAEPILFGHVIDTIADKSDTLVTLAVWMCFGISNIIAYVLVARGADRLAHRCRLTVLEKSFARIISMPLIWHQQRGTSHALHTLLRATDSMSSIWLEFMRQHLSTFVALFVLVPVTFKMNWRLSIVLMVLAILYILIARLVMQKTKNGQAAVEHYHHNLFKHITDSISNVSIVQSYNRITEETSALHQHTNNLLSAQTPVLNWWALASGLNRMASTISIVCVLLLGAFFVIKGQLSVGEVVTFVGFSQLMIGRLDQISGFINLAVSSQAKLQEFFDMEDSTFQTNEPANLPSLPNVKGAIQFHHVTYEFPNSSQGVFDISFEVKAGQTVAIVGPTGAGKTTLINLLQRVYDPTVGYISIDGININSINRESLRKALATVFQDAGLFDRTIRDNISIGKTGATDEELYEATKTASAHDFILKKSKNYDTLVGERGSQLSGGERQRLAIARAILKNAPILILDEATSALDVETEIRVKNAIDCISQNRTTFIIAHRLSTIRNADLVLFLDQGRLIEKGSFQELINKDGHFYKLLKRGGLTINQPATKEKDDNIIPLRKAMAL
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_STRA5
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: VE7_HPV57
Sequence: MHGERPSLEDITLILEEIPEIVDLHCDEQFDNSEEDTNYQLTEPAVQAYGVVTTCCKCHSTVRLVVECGAADIRHLEQLFLNTLTIVCPRCV
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: MOAA_SALA4
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNNGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNGYRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELIKRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ALG14_ASPFU
Sequence: MFSMLRRMKLDPSTYTYRTYVVSSGDNFSAARAVEFETEWLKQSPKLSFPANGSNSTESYAVVTVPRARRVHQSYLTAPLSTLQCFYACFLVLCGRHPEQKSPLPTTNSPYPDVILTNGPATAVCMVLAAKSLRLFHYLKSLFYIKDHQDRDSSRSSQVKRSEDAPAPVHFQLRTIYVESWARVTTFSLSGKLLLPFADRFLVQWPDLAGKQAWRGMRETEYAGTLVD
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit alg13 to the ER (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit alg14, Asparagine-linked glycosylation protein 14.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: APT_CYAP4
Sequence: MDLKSLIREVPDFPKPGILFRDITTLLQNEQGLRYTIDRLTQAFSDQAIDYVAGIESRGFIFGAPLAYKLGAGFVPIRKAGKLCAEVHTVEYALEYGTDRLEIHKDAIHTGGRVLIVDDLIATGGTAAAAAQLITLCGGDLVSYAFIIELQDLGGRKNLPDVPIKVLVEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB7_ARATH
Sequence: MESREDSFISKEKKSTMKKEKQAIASQRNRRRVIKNRGNGKRLIASLSQRKRRRIPRGRGNEKAVFAPSSLPNDVVEEIFLRLPVKAIIQLKSLSKQWRSTIESRSFEERHLKIVERSRVDFPQVMVMSEEYSLKGSKGNQPRPDTDIGFSTICLESASILSSTLITFPQGFQHRIYASESCDGLFCIHSLKTQAIYVVNPATRWFRQLPPARFQILMQKLYPTQDTWIDIKPVVCYTAFVKANDYKLVWLYNSDASNPNLGVTKCEVFDFRANAWRYLTCTPSYRIFPDQVPAATNGSIYWFTEPYNGEIKVVALDIHTETFRVLPKINPAIASSDPDHIDMCTLDNGLCMSKRESDTLVQEIWRLKSSEDSWEKVYTIDLLSCSSSSLSEFRDGFNWTRKDLVEPSTPVAICKDKKILLSHRYARNMIKYDPQIKSISLIYQPPLCRRYASYFQSLISHI
What are the official names of this protein?
Putative F-box protein At1g12855.