PharMolix/UniProtQA huggingface dataset:
Protein: UNC55_CAEEL
Sequence: MQDGSSGAASLGNSSPDATDCVVCGDKSSGKHYGQFSCEGCKSFFKRSIRRSLSYTCRATKNCAIDVQHRNQCQYCRLTKCIRMGMRKEGRRSNETQTAVSAVQRGRLPVTMPSLFPPNMFLRSPFPFMSVPFNPLMTAQFTKPSIKESIFEFAAQTIFATVNWARTSMSNLVKGDQLILLRHSWTPIFIFALAQSNFALNLSTHLTAVTATAASTENGSSSLGSKSEDEEKSEEKPERVFDEPQFQGFQAKIDKIRDFHLDVVESSSLRAVLLFSCDEEALEEKGKIEEIVEKLKSAVDEYCKMNKRSERYHQICECLQLLKSTRNLPISRLFFSRLLGTTPLETILSDLLITPPPPTLPFFPQLPSRN
What is the function of this protein?
Required for normal locomotion.
What are the official names of this protein?
Nuclear hormone receptor unc-55, Uncoordinated protein 55.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_BRUAB
Sequence: MSAPRTLYDKIWDDHVVDQQEDGTCLLYIDRHLVHEVTSPQAFEGLRMAGRPVRHPEKTLAVVDHNVPTSPDRINGIQNEESRIQVEALARNAADFGVEYYSERDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGKLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAPDETTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGSSPEDVVSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRIEDLRAAAKVVEGKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIEAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIRAWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SEC11_OGAPD
Sequence: MNLRQQLGSGLSMAMVLASAFAFWKLFSIVTMSNSPIVVVLSGSMEPAFQRGDVLFLWNREEYVGVGDVVVYKLQEKDIPIVHRVVREHRVMEKDRKTKKKVQKQLLLTKGDNNERDDLPLYAYGQQYLERKKDILGRVFGYVPLVGYVTILITENVYFKYALMALLGLSALVQDE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TTCA_CHRVO
Sequence: MNAALDDKAAKKAAFEGNKLAKRLRHHVGDAINDFNMIEEGDRVMVCLSGGKDSYTLLDILRGLQKSAPINFSIVAVNLDQKQPGFPEHVLPEYLKSIGVEYRIVEEDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVADELGATKIALGHHRDDILHTLFLNMFYGGKMKAMPPKLVSDDGRHMVIRPLAYCREKDIIRYADWKAFPIIPCNLCGSQPNLQRQVVKEMVNDWDKRFPGRVESMFRALQNVVPSHLADPKLFDFVGLQTGDAPFADGDTAFDKEEFRDPAPDADDVEDAPKKRTISILDSRGKESGCGA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS16A_WHEAT
Sequence: MSIVRRSNVFDPFADLWADPFDTFRSIVPAISGGSSETAAFANARVDWKETPEAHVFKVDLPGVKKEEVKVEVEDGNVLVVSGERSREKEDKNDKWHRVERSSGKFVRRFRLPEDAKVEEVKAGLENGVLTVTVPKAEVKKPEVKAIEISG
What are the official names of this protein?
16.9 kDa class I heat shock protein 1, HSP 16.9, Heat shock protein 16.9A, Heat shock protein 17, Low molecular weight heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM5_ENTH1
Sequence: MEKEQLPELKYINVNDFNINEKVIGIPVQTNEVAKYMKMFKGLCYNRIKTKCVIPYNSERMILLETPLKEQTQKLIQDNHLKTVETEVPLTIKNFNVNEIMKRYINKNIQLPSSFETVGTLAHMNLKEEQMEFKYIIGEAFLIKNYPRIQTVITKTAEISNEFRTFPLEVIAGIPNTEVTVICHGVKFVLDYAQCYWNTRLETEHIRIINQMKAGEILCDAFAGVGPFAIPAALKGVKVYANDLNPTAVKYMRINAVNNKTTIECDNMDARDYLRKIVLEKHIQPNYILMNLPATAIEFLDCIPELYLQHCMIHCYGFSPLPNAEDLKKKAFELLKGEYPITIREVRDVAPKKVMYCLSIFIESTKHLTSGNNVPEAKKTLN
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
Protein: ASPH1_HUMAN
Sequence: MKEGRGSFSVERGPRKERETAQSGMWKGNSPAGSQGAAMEGTGGELGGQGNWGPEDAPGLLARASLIMLPWPLPLASSALTLLFGALTSLFLWYCYRLGSQDMQALGAGSRAGGVRGGPVGCSEAGGPSPGGPGDPGEGPRTEGLVSRRLRAYARRYSWAGMGRVRRAAQGGPGPGRGPGVLGIQRPGLLFLPDLPSAPFVPRDAQRHDVELLESSFPAILRDFGAVSWDFSGTTPPPRGWSPPLAPGCYQLLLYQAGRCQPSNCRRCPGAYRALRGLRSFMSANTFGNAGFSVLLPGARLEGRCGPTNARVRCHLGLKIPPGCELVVGGEPQCWAEGHCLLVDDSFLHTVAHNGSPEDGPRVVFIVDLWHPNVAGAERQALDFVFAPDP
What are the official names of this protein?
Aspartate beta-hydroxylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
Protein: Y112_ABVP
Sequence: MSCQIYPSQMCPGKAYKNCKLNIMNFWEVICIYYFALQGSFLGILVNLPILVTTLPLLPPALFFYLMYLFALPLKDIFNIFFPSLDPILIPILIFFLVGVSRARLSKVFKWR
What are the official names of this protein?
Putative transmembrane protein ORF112.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: CFT1_KLULA
Sequence: MNVFDEILQPTVVNKCLHGNFTSAEREEYVVARTNVLSVFRVSRAQKLVLAYEWKLAGKIIDMQLLPQIGSPLKMLAILSSKSKVSLVRFDPVAESLETLSLHYYHDKFVNLSTSSLKTESIMAVDPLFRCLLVFNEDVLAILPLKLNTEDMEIDEDENGIKEPMAKRLKRNQGITSDSIIMPISSLHKSLKHVYDIKWLNNFSKPTVGILYQPVLAWCGNEKVLGNTMRYMVLSLDVEDEKTTVIAELADLPNDLHTLVPLKRGYVLIGVNELLYISASGALQSCIRLNTFATSSINTRITDNSDMNIFLSKSSIYFYKALKRHDLLILIDENCRMYNIITESEGNLLTKFDCVQVPIVNEIFKNSRLPLSVCGDLNLETGRVLIGFLSGDAMFLQLKNLKVAFAAKRQLVETVDDDDDEYSALYGESQNNTHTRIVETQEPFDISLLDSIFNIGPLTSLTIGKVASVEPTIQRLPNPNKDEFSIVATSGVGRGSHLTALHSTVQPHIEQALKFTSATRIWNLKIKGKDKYLVTTDADKEKSDVYQIDRNFEPFRAQDFRKDSRTIGMETMDDDKRILQVTSGGLYLFDVDFKRLARLTIDIEIVHACIIDPYILFTDARGNIKIYQLDSKNKKKFIKFKLPEALNEIIITSGSIFKSNICNKFLHGLENSSQEQLLFTFVTGDNQVIFFTEKHNDRIFQLNGVDQLEDMLFISTYQIPEEMNPDPSIKQIMLNRLGHHKKEEFLTILTFGGEIYQYKKSTKHSGKLLKCKSHPLITGAPNNAYPQGVNKIERVAHYFPNYNGYSVVFITGQVPYIIIKEDNSVCRIFRMTNIPIVTMARWGKNSVMCVDNIKNARVMKLDPECYYGNTQILRKIIIEDVVEEFETLGNIAYHERTGMYIISYTKFIEYQALSEDGEPLVGYDPSKPNSTGYKSGLLLINPLTWNIIDRLDLSENSMVNDIKTMLIQLNSKTRRKRELVIIGSSFVKEEDQPSTGCLLVLDITEVVAEPGKPDSNFKFKQLFEEEIRGSVNAVCEISGRFMIGQSSKALVRDMQEDNSAVPVAFLDMPVFITDAKSFSNLMIIGDSMQGFTFVGFDAEPYRMIVLGKSTSKFQVMNLEFLVNNGNINFIVTDRQNHLHVLRYAPDEANSLSGQRLVHCNSFNMFTTNNYMKLVRKHVEFGSKTSNYIALGCQTDGSIFRMIPLNEASYRRFYLVQQQLLDHEIPLAGFNTKMERLDNEYYHKGHSLRPTLDSQVLKKYIHLPITKRTTIENRVGRHASTELWHDLIDIEFSLRSLTNSN
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
What are the official names of this protein?
Protein CFT1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SC23D_ARATH
Sequence: MAVRATVSRFPIDSDAQEASGLPWGLTVTPFAAKDENGIGPACGSNGHLLPRCENCYAYFNTYCELDQWAWNCSLCGTLNGLPSDAIARYSNPHSIPEMTSSFIDLEMPLDGSEEEMTQARPVYVAAIDISSSEEFLELTKSALLAALEALSPGALFGLVTFSHKIGLYDVQGPIPVVKNVFIPPDGESSLSLELEDVMPLLQFLAPVETCKDRIAAALETLRPITSWERSAGAGQGMDSVLMGGRGFGTAMEALFNYLGSEFGNTFALARVFAFLSGPPDYGRGQLDTSRYGEQYASKRVDADRALLPEQTPFYKDLATIAVQSGVCVDLFAVTNEYTDLASLKFLSIESGGSLFLYSSTDDSTLPQDMFRMLNRPYAFNCVLRLRTSTEFKPGNSFGHFFPDPQYENLQHIICCDSYATYAYDFEFADNTGFSRHSGEQPVVQIAFQYTVVVPPEGLSNSEMSSSSRGKHTLQRRLRIRTMQFGTAHNINEIYDSVDHEVVLSLLVHKVILASLEDGVREGRALLHDWLVILTAQYNDAFNLVQYKNGNKSMSSQIDITFSQCPQLEPLPRLVFALLRNPLLRFHEEGVHPDYRIYLQCLFSVLDPSSLHCGIYPALMSYSTPDTLAYPRHSLSRAALITSGSPIFFLDAYTTLIVFYSSTADPSIPFPPPQDCLLRQTINKVKQERSITPKLVFIRGGRDDATVFENYLIEEQDVDGNGFASAMGFVSFLDDISQRVTEYMK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).  May contribute to COPII-coated vesicles formation and ER-Golgi vesicle transport (PubMed:29390074).  Together with SEC23A, essential for pollen wall development and exine patterning, probably by regulating endoplasmic reticulum (ER) export of lipids and proteins (e. g.  sporopollenin) necessary for pollen wall formation (PubMed:29390074).  Also involved in plastid physiology in anther tapetal cells (PubMed:29390074).
What are the official names of this protein?
Protein transport protein SEC23 D, AtSEC23D, Protein transport protein SEC23/SEC24-like 1, AtSec23/Sec24L1, Protein transport protein SEC24 D.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
Protein: RRF_PROMT
Sequence: MSNQELKTTMSKSIEAAQRNFNTIRTGRANTSLLDRISVEYYGAETPLKSLATITTPDSQTIAIQPFDLGSLASIEKAIATSDLGFTPNNDGKIIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRREAIDRVKKSEKDGDLSEDQSRDEQETIQKETDNFIKDIEKKLSEKEAEILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_RHOPS
Sequence: MAPPRKLHIKSYGCQMNVYDAQRMVDVLAPEGFVETATVDDADLVILNTCHIREKASEKVYSELGRLRLARDEAASSGRRMQIAVAGCVAQAEGEEIVRRAPVVDVVVGPQSYHHLPQLLARADQAGRALETEFPVEDKFGFLPQPRPETIRARGISAFVTVQEGCDKFCTFCVVPYTRGAEVSRPVSAIIDDVKRLADNGVREITLIGQNVNAYHGEGPDSRAWTLGRLLRRLAAVPGIVRLRYSTSHPNDVDDELIEAHRDLDALMPFVHLPVQSGSDPILAAMNRKHTAADYRRVIDRFRAVRPQIAFSSDFIVGFPGETEADFAATLALVTQIGYAGAYSFKYSPRPGTPAADMQEMVPAAVMDERLERLQQLIDSQQSAFNKAAIGQTVDVLFERAGRKPGQIVGRTAYLQPAHVFPGPMFLGPGMAPDSLVGQILPVRVDSLERYSLLGELAAKPPQHARPLAATGA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_MYCUA
Sequence: MAPKAVLVGLPGSGKSTIGRRLAKALGVSLLDTDAAIEQQAGRSIAEIFATDGEEEFRRIEEEVVRAALVDHDGVLSLGGGAVTSPGVRSALDGHTVVYLEISAAEGVRRTGGSNVRPLLAGPDRAEKFRALMSQRIPLYRRVSTIRVDTNRRNPGAVVRYIMSRLDDPTPNTSPSSTASGAAT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_STRP6
Sequence: MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKVILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMALSKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFARDIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALKIEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMINPITGTTYAMFEPALDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEESLLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELESLTKIDLFFLDKLLHIVEIEQELQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRAMRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQGVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAQSLSDAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQPQGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEHPILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQETIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIATKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSDTSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAAYFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQGVPLFTALDTAKAMLTVLESRCFNIEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RL9_BEII9
Sequence: MDVILLERVAKLGHMGDIVRVKNGYARNFLLPGGKALRATEANKKHFESQRAHLETRNQELRDQAAAIGEKLDGQTFVIIRQAGETGQLYGSVSPRDIAEAAIAAGFDVHRNQIALTTPIKTIGLHEVPVVLHPEVSVNVTVNIARSPVEAERQAKGEEINVVEETNLDELGLEIGAALADAGGSLGDR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PYRD_SULNB
Sequence: MPFFSYDTVKKILFNFDPETAHTLAGIGLRALPCCPPLLHFITKQYFVTDPMIEQEFFGRTFKNPVGLGAGFDKNGQYITSMPALGFGFTEIGTVTPKPQPGNPKPRLFRLLEDRSIQNAMGFNNRGMGYMLEQLNKLYFFDYPIGINIGKNKVTSEEKALEDYETLFHAFKDYGDYIVINISSPNTPGLRDLQNEQFIKDIFAMAKRITEQPVLLKIAPDMTHEDAIALCNTAVDAGAAGIIATNTTIDYSLTPHAKDFGGISGALLTEKSYQLFKAIGKELYGKTLLISVGGIDSAEEAYRRIKAGASLVQVYSMLIYKGPALIREINEGLIKLLKKDGYTHISEAIGADWK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PTC1_CAEEL
Sequence: MLTLLEPPGAKRSPTVGNYNNRSAQHLLNLAPEEDDLYETYEETEDYAENEPTGNILTRSFQFLDQYLVGQSSSADYNDRWKREFRARPSWCDADLCLQQMNRGKATGNRYALYSRSLIQKLLFALGNTVHRNAWSIILAVSMIFAVCCYGLQYVHIETDIVKLWVAQGGRLDEELNFLPNIKEAMRNVTGDSGPELPRENGLGGGYQVLIQTPEYEGQDALAAGPLLKHVEIMKHIASFNVSVHGVDWSLSDICFKPAPPSVAADSAASSLGDVIDKIVPCIWITPIDCFWEGSKALGPHPSLPKSSLGPLGMLLSSLSDGDMIRWSDFDPIAVIDEIHRSFNLGSHYTFFERAGVSHGYMDRPCIDPLDPECPPMAKNYFDVCPHIDRVREIAKKYGTELEEEKKKDSGYSFFDFLGRKKREAGDQPKMIHPAQPADSIPTIEDAVPAQVPVSTAPIPTTTTLSPEEARAAEEKEKKQKARELKDYCKSYRKSAFEWLKKNKDKWPEVMSENMYPQNVDYAAEMTGGCSGFASNVLNWPEDMILGNPRRAKKGGKLSGADALQSVFLVASPADVFLRFKQKPGRNSMKTGLDMDAWNETAAEQVLQAWQRNFTKSLYNHKANVDEDGNERRTLHPLASTSIADMLEEFCQFNYTIILAGYALMLAYAIVTQARFDNCLPATESSMGLALAGVLVVTFASVAGLGLATWFGIEFNAATTQIVPFLTLGIGVDNMFMLLHNYRDVVKLAGGHAEMAILMRETGMSILCTSINNILSFLTGTLLPIPALRSFCAQSSILLTFNFIAILTIYPAIISIDLRRKKAQRRDLVCCLYGDTREESYSMISKPKIQSKRIIGAPSEASIMQQFDGITQAQMASSDDPAPWSLHSFIRYYYIPFISKPASKVAIIVGCCALLGASFIGMRQSTLGLELGDVLPEHTAPAQFLRARDKYFSFYPMFAVIKGPNIDYAHQQRQIDNYRQSIGSSKYVIKNKNEEPSEKYWLGLMRDWLISIQRGFDEEVAKGSFNLTSGTVIGSNVSEDARLAHALMCSHGSLFGCAGRVGKIRLVDASGIINSDGFYNYLTAWFNVDHMMYYVSQASFFPTPPKWELSKNHTENFIPAAEPLAYSQIPFYLTGLTDTAVIVDAIKDIRSVCERFTDQGLPNFPQGIAFTFWEQYLFLTGNLMQAISIITISVFCVISVLLFNPWAALMVVCILGIMTCELAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSFLTALGTRSQRTSSAVDRVFVPVIHGSFSTLLGILMLGFSEFEFVVKYFFIVMTALICIGIINGLILLPVLLSWFGPRREISPTGGKTTLTLPPPLPKNANSSRSGGDDSDEDDEPSGLVMYSRQAPPTTRTSGGNRGTVGNNTRRLPAV
What is the function of this protein?
Required but not essential for cytokinesis of mitotically proliferating germ cells.
What are the official names of this protein?
Protein patched homolog 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Highly concentrated in a punctate pattern at the apices and internal membranes adjacent to the rachis. Expression is more intense in the distal proliferative region and in oocytes of the gonad arm.
Protein: FLIW_BORBZ
Sequence: MIDEKSIEFDFPEGILGFENIKKFIIKDSKYKPFSIMQSINKDVSFLVTSPFNFLSEYLPNIQEKDWSDIKAKEEDEKVILCIINMHVNDYKDITANLKAPIIINKKKLLGKQAICTNEKYSLHHKVFKE
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHLL_BACT3
Sequence: MTVKKLYFIPAGRCMLDHSSVNSALTPGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTFVEGQILPKMTEEDRIVNILKRVGYEPDDLLYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKECILPHLNYKIIEGDYEVVPGVQLLYTPGHSPGHQSLFIETEQSGSVLLTIDASYTKENFEDEVPFAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI
What is the function of this protein?
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer.  Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL (By similarity).
What are the official names of this protein?
N-acyl homoserine lactonase, AHL-lactonase.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: SRRM1_PONAB
Sequence: MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPTSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS
What is the function of this protein?
Part of pre- and post-splicing multiprotein mRNP complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Involved in numerous pre-mRNA processing events.  Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome.  Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex.  Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions.  Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
What are the official names of this protein?
Serine/arginine repetitive matrix protein 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
Protein: VE1_HPV07
Sequence: MADDSGTEDVGSGCSGWFLVEAVVDKQTGDVVSEDEDEDAIEDSGYDMVDFINDTVVSEHEELSNAQALLHAQQTCADAVELCELKRKYISPYVSPIQCSEPSVDGDLSPRLHAIKLGGGKKAKRRLFERLEQRDSGYGYSQVETTETQVEEEHGEPEGIEGGSGRAATVETEAVEVLEESSDVIQQLSPRTQVVELFKCKDLNAKLCGKFKELFGVGFHDLVRQFKSDKSTCTDWVYAVFGVNPTIAEGFHTLLKGQALYLHTQWTTCRWGMVLLALCRYKVAKNRETVVRQLAKMLNVPDNQLMVQPPKLQSSAAALFWFRSGMGNGSEVSGTTPEWIAKQTMLEHSFAEAQFSLTQMVQWAYDNGHTDECEIAYYYAQIADIDANAAAFLKSNNQAKYVRDCAAMCKHYRLAEMRRMSMADWIKHRGEKCDEGDWKPIVKLLRYQHIDIIVFLAALKKWLHGIPKKNCICIVGPPDTGKSCFGMSLMHFLQGTIISFVNSCSHFWLQSLVDAKVAMLDDVTSACWAYMDTHMRNLLDGNPTSIDRKHKSLAVIKCPPLLLTSNINIKHDCKYQYLQSRVTVFEFPNPFPFDSNGNAVYELSDANWNSFFKRLASSLELQTTEDEDGETSQAPRFVPGTVVRTL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PLSX_LEPIN
Sequence: MMWVAVDVMSGDYGPEKIIEGAVNAVNQDGANVVLVGKEEEIGEILLKFEYDTNKVRIQHASEIIDMNDSPSIAVRTLQDSSIVQATQIVADKTCVGMFSPGNTGATMASALLYLGRIPGVLRPPIAAPIPQENGPPMLLVDAGANVDCKPDYLAQFAVMGEIYSKLIFNILNPKVGILSNGEEDKKGNTVSLKAFEMIKKLPINFVGNVEGRDLYGSGKDVDVVVCDGFIGNIVLKATEGLSKSIFNVLRESIKQSSLAQTGALLLKPTLGAIKKRLDYAEYGGALLLGVDGICLIGHGSSNALAVQSAIRVAVECAQHQINDRIAADLKKYNI
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RNPH_LISIN
Sequence: MRFDGREKNALREIEVTPDYLMHPEGSVLIASGNTKVICSASVETKVPPFMRGEGRGWISAEYSMLPRATNTRNIRESSKGKVTGRTMEIQRLIGRALRAVVDLDALGERTIWLDCDVIQADGGTRTASITGAFIAMVMAIAKLDEEVPFTKFPVKDFLAATSVGVLEEGGTVLDLNYVEDSAAQVDMNIIMTGSGAFVELQGTGEEATFSETELAELIALGKKGISELIEIQKETLGDKITARIKGE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.