PharMolix/UniProtQA huggingface dataset:
Protein: PAFA_CAVPO
Sequence: MAPPKLHTLFCLSGFLALVHPFDWRDLDPVTYIQSSVWIQRIQSELLITSFGHTTIPKGNGPYSVGCTDLMSGYTNQSSFLRLYYPSQDNDFPDALWIPNEEYFQGLTETLGASSFLGKLLKLLYGSVKVPAKWNSPLKTGEKYPLIIFSHGLGAFRSIYSAIGIELASHGFIVAAVEHRDESAAATYYFQDAPAAESGNRSWIYYKVGNLETEERKRQLRQRGEECSQALSWLLSIDEGEPVKNVLDLNFDIQQLKGSLDRSKVAIIGHSFGGATVIQTLSEDQRFRCGIALDPWMFPVGEDVHSKIPQPLFFINSEYFQSANDTKKIEKFYQPQKERKMIAVKGSVHHNFVDFTFATGKIIGQMLSLKGKIDSEVAMDLINKASLAFLQKYLGLDKNFDQWNSLMEGDDENLIPEFTIPTTMQSSTGTEQRNPD
What is the function of this protein?
Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response (By similarity).  At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (By similarity).  Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position.  Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups (By similarity).  Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells (By similarity).  Hydrolyzes oxidatively truncated phospholipids carrying an aldehyde group at omega position, preventing their accumulation in lipoprotein particles and uncontrolled pro-inflammatory effects (By similarity).  As part of high-density lipoprotein (HDL) particles, can hydrolyze phospholipids having long-chain fatty acyl hydroperoxides at sn-2 position and protect against potential accumulation of these oxylipins in the vascular wall (By similarity).  Catalyzes the release from membrane phospholipids of F2-isoprostanes, lipid biomarkers of cellular oxidative damage (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, LDL-associated phospholipase A2, LDL-PLA(2), PAF 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Associates with HDL particles in plasma.
Protein: TPM4_DROME
Sequence: MDAIKKKMQAMKVDKDGALERALVCEQEARDANTRAEKAEEEARQLQKKIQTVENELDQTQEALTLVTGKLEEKNKALQNAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLIVEKERYCMIGDSLDEAFVDLIKGLEPFWNPRNPKPPTPKLPTPTPEELAAMEEARAAAEAAAAAEAEAAEAAAAAGEAGPDGAPAAPGEEKAPAKEPTPPKEPTPPPPPPPPFEYSIDLPPEGAEVPYVKNYEPPPPGSEPEPVPAAEGEAAPAAEGAAPPAEGAAPPAEGAVPPADGAAPPAEGAAPAAEGAAPPADGAAPPAEAAAAPADAAAPAAEAAPAEAPAAEATAAEAPPAEAAPAEAAPAAAEGEAPPA
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin-1, isoforms 33/34, Tropomyosin II.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL30E_CALMQ
Sequence: MIDISRELQVVANTGRLTMGVRQSIKAILNGDAKLVIMAANVPPSIRQDVERYAKLSQVPVFTYAGTSWELGGALRRSHKIAVVAIIDPGESSIMSLAGGANV
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: MDH_SHEPA
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTAVEVKGFAGEDPTAALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLVEKCAATCPKALIGIITNPVNTTVAIAAEVLKNAGVYDKNRLFGVTTLDVIRSETFVAEAKGLNVADVKVPVIGGHSGVTILPLLSQVEGVSFTDAEVAALTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANVVECAYVDGGSEHAEFFAQPVVLGKNGVEEVLAYGEVSAFEANARDAMLDTLQADIQLGIDFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: MLTC_YERP3
Sequence: MKKILALLVIAPLLVSCSGNKNQVENEVFVKDTNGFEILMGQFAHNIENIWGLKEVLIAGPKDYVKYTDQYQTRSHINFDAGTITIETIATTNPAAHLRQAIITTLLMGDDPGSIDLYSDVNDIQISKEPFLYGQVLDNNGEPIRWEWRAAHFADYLLQNKMQTRTSGLHVISFVTIQLVPNHLDKRAHKYLPLVRKSAARYGVEESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFKLKGKSGQPSRSYLFDPENNIDAGTAYLSILQNTYLGGIQNATSRRYAVITSYNGGAGSVLRVFHSDKNKAVGIINTMSPGDVFQTLTTKHPSGESRRYLVKVNSAQKNYRRY
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ATS18_MOUSE
Sequence: MECALLCLCALRAAGPGPPWGPAGLGRLAKALQLCCFCCASVAVALASDSGSSGGSGLNDDYVFVVPVEVDSGGSYISHDILHHRKRRSAHGASNSLHYRVSAFGQDLHLELKPSAILSSHFRVQVLGKDGASETREPEVPQCLYQGFIRNDSSSSVAVSTCAGLSGLIRTRDNEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEKRVRWYQDYPGSQRTYPGHSPSHTPPASQSQEPEYSHRRWQKRHFCGRRKKYAPKPPAEDAYLRFDEYGGTGRPRRSAGKSQNGLNVETLVVADAKMVEKHGKDDVTTYILTVMNMVSSLFKDGTIGSDINIVVVSLILLEEEPEGLLINHHADQSLNSFCQWQSALVGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMVHDGEGNPCRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQTGQYKYPDKLPGQIYDADMQCKWQFGAKAKLCSLGVMKDICKSLWCHRVGHRCETKFMPAAEGTACGLSMWCRQGQCVKLGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCSNPKPQYGGKYCPGSSRIYKLCNINPCPENSLDFRAQQCAEYNNKPFRGWLYRWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPHRNDVCIDGICELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLSQHKANEYYPVVTIPAGARSIEIQELQLSSSYLAVRSLSQKYYLTGGWSIDWPGDFTFAGTTFEYQRSFNRPERLYAPGPTNETLVFEILTQGKNPGIAWKYALPKVMNVTQPATKRYHHTWRTVQSDCSVTCGGGYISIKAICLRDQHTQVNSSFCSVRTKPATEPKICNAFSCPAYWLPGEWSACSKSCAGGQQSRKIRCVQKKPFQKEEAVLHSLCPVSTPTQVQVCNSHACPPEWSPSPWSQCSKTCGRGVRRREVLCKSPAAETLPESLCSSSPRPEAQEGCVLGRCPKNNRLQWIASAWSECSATCGLGVRKRELKCVEKTLQGKLITFPERRCRNIKKPSLELEEACNQRTCPVYSMAVASWYSSPWQQCTVTCGGGVQTRSVHCMQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKKDDPSCVDFFSWCHLVPQHGVCNHKFYGKQCCRSCTRKS
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 18, ADAM-TS 18, ADAM-TS18, ADAMTS-18.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: QUEF_STAEQ
Sequence: MTQGRQKDELKDITLLGNQNNTYEFDYRPEVLETFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNIKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLINLMDPHYIEVWGKFTPRGGISIDPYTNYGRPDTKYEKMAEHRLMNHDMYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP3S_DICDI
Sequence: MIKSILIINNHGKPRLIKFYEHYSEEKQQQIIRELFLLVSKRTERSCNFLEIGNNSNIFDKDTKIIYRHYATLFFIFCVDSSESELSIIDLIQTFVESLDKCFENVCELDLIFHIDKVHYILDEMVMGGLVLETNPTIIFSNYEIQNKLEKAENPLLSGLAGVMQTIKPNK
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
What are the official names of this protein?
AP-3 complex subunit sigma, AP-3 complex subunit sigma-3, Adaptor-related protein complex 3 subunit sigma, Sigma-adaptin 3, Sigma3-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Endosome membrane.
Protein: LON2_BACSU
Sequence: MSWTGIALFIQLFFGIIIGLYFWNLLKNQRTQKVTIDKESKKEMEQLRKMRAISLSEPLSEKVRPKSFKDIVGQEDGIKALKAALCGPNPQHVIVYGPPGVGKTAAARLVLEEAKKHKQSPFKEQAVFVELDATTARFDERGIADPLIGSVHDPIYQGAGAMGQAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLDSAYYSEENTQIPNHIHDIFQNGLPADFRLIGATTRMPNEIPPAIRSRCLEVFFRELEKDELKTVAKTAADKIEKNISEEGLDLLTSYTRNGREAVNMIQIAAGMAVTENRKDITIEDIEWVIHSSQLTPKHEQKIGVEPQVGIVNGLAVYGPNSGSLLEIEVSVTAAQDKGSINITGIAEEESIGSQSKSIRRKSMAKGSVENVLTVLRTMGMKPSDYDIHINFPGGIPIDGPSAGIAMAAGIFSAIHKIPIDNTVAMTGEISLNGLVKPIGGVIPKIKAAKQSGAKKVIIPYENQQAILKQIDGIEIIAVKTFQEVLDEILVNPPTEQKPFHIEINKESV
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).
What are the official names of this protein?
Lon protease 2, ATP-dependent protease La 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIPC3_HUMAN
Sequence: MEGAAAREARGTETPRASAPPPAPSEPPAAPRARPRLVFRTQLAHGSPTGKIEGFTNVRELYAKIAEAFGIAPTEILFCTLNSHKVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGDSIEAINDHSIVGCRHYEVAKMLRELPKSQPFTLRLVQPKRAFDMIGQRSRSSKCPVEAKVTSGRETLRLRSGGAATVEEAPSEFEEEASRKVDDLLESYMGIRDPELASTMVETSKKTASAQEFARCLDSVLGEFAFPDEFVVEVWAAIGEAREACG
What is the function of this protein?
Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion.
What are the official names of this protein?
PDZ domain-containing protein GIPC3.
What is the protein family that this protein belongs to?
Belongs to the GIPC family.
Protein: MURA1_STRPM
Sequence: MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMIYMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDRGYYQFHEKLAKLGATISRSSEV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_SERP5
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: COMM2_AEDAE
Sequence: MIDSLESKITFEIPNNLDFNKFIRENNYSSFWQNLHQQETAARVAAMSSLGMGVSEPLRTSEYNASDFNLLSSLQNFAGRAGPVGFSADGSEQLLDPTYERFIGDVWVGIVLTLMILSSIFCMCSCFLYHKFRQWQRSVLTARSQTLSSMDLETPPPYDVESLPSYTIVSGLPSYNDAIEQLKQKQQQKSPGGHLEPVKLQRPSVIKLFESQSQDLLAGAKLEEIRYNFANNLTTSVVSENSFDVTPTTSSNTAVNATTVAVAPNFKTQVSTSMPKKFTVCNYSVENERSGS
What is the function of this protein?
Essential for nerve cord development.  Functions downstream of fra to control axon guidance across the central nervous system (CNS) midline.
What are the official names of this protein?
Protein commissureless 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the commissureless family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: KCY_STAA1
Sequence: MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUGA_VESVE
Sequence: NLNRTNWPKKIFNIYWNVPTYFCHQHDVYFNELTKFDIKYNPKGNYRGDTISLFYDPGNFPAMVPLKNGTYDIRNEGVPQKGNITVHLQQFTKELDEIYPKKISGGIGVINFNKWRPIFRRNVNNLKINKEVSIDLVRKEHPKWDKSMIETEASNRFEKSARIFMEKTLKLAKDIRNKNKWGYHGYPYCPTASTGNPSFDCDALAMNENDKLSWLFKYQDVLLPSVYVKHVLKPEEKIGLVRGSVKEAVRISKKFEHLPKVLSYWWYAYEDKMDTFLTETDVKNTFREILINGGDGIIIWGTMHDLNKEKCEKLKQYLSTILGPIAFKVMEAVKKRTPLNF
What is the function of this protein?
May hydrolyze high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase A, Vesp v 2A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSM8_YEAST
Sequence: MSATLKDYLNKRVVIIKVDGECLIASLNGFDKNTNLFITNVFNRISKEFICKAQLLRGSEIALVGLIDAENDDSLAPIDEKKVPMLKDTKNKIENEHVIWEKVYESKTK
What is the function of this protein?
Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, spliceosomal U4/U6. U5 snRNP, and free U6 snRNP).  It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  It probably also is involved in degradation of nuclear pre-mRNA by targeting them for decapping.  LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.  LSM2 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm8.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KATG2_CUPPJ
Sequence: MSTEAKCPFNHAAGSGTSNRDWWPHQLNLGILRQHSSLADPMDKGFNYAEEFKSLDLAAVKHDLAALMTVSQDWWPADFGHYGGLFIRMAWHAAGTYRTGDGRGGAGSGQQRFAPLNSWPDNVNLDKARRLLWPIKQKYGKKISWADLIVLTGNVALESMGFKTFGFGGGREDVWEPDQDVYWGSETTWLADKRYSGVRDLENPLAAVQMGLIYVNPEGPNGNPDPAKAAVDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASHVGPEPEAAGIEEQGLGWRSSFGSGKGSDAITSGLEVIWTSTPTKWSNNFFWNLFGYEWELTKSPAGAHQWKPNGDAGANSIPDPYDPSRRRGPTMLTTDLSLRVDPAYEKISRRFHENPDQFADAFARAWFKLTHRDMGPRSRYLGPEVPAEELIWQDPIPAVDHVLIDEQDVAALKGKILATGVPVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEVNQPAVLAQVLETLEGIRNEFNSSQSGGKKVSLADLIVLAGCAGIEQAAKKGGHDVKVPFTPGRMDATQEQTDVESFSVMEPIADGFRNYLKGTYAVTAETLLVDKAQLLTLTVPEVTALVGGMRVLNANFGQTQHGVFTDRPETLTNDFFVNVLDMGTEWKPTADNKDLFEGYDRATGKLKWTGTRVDLIFGSNSELRAVAEVYGCADAKEKFVQDFVAAWNKVMNLDRFEAANR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: HIS6_STRMU
Sequence: MLKKRIIPCLDVKDGRVVKGVNFVNLTDVGDPVDAARAYYEAGCDELVFLDITATSDNRETTVDMVRHVADQVFIPFTVGGGIRSVDDMNKMLKAGADKVAVNSSAIANPQLIKDCAEKFGSQCVVVAIDARKEADDSWHVYVAGGRKDTGIDLLAWVKEAVQLGAGEILLTSMDKDGTKSGFDLDMLNAVAQLADIPIIASGGAGNMEHMVEIFEKTPATGALAASIFHYGEVSIADTKKAMKEHGIEVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_LEPBJ
Sequence: MTVSREEISTILDDALFLPVKLYSLKVNQRPNHSLIEVVLDNLEHPYGSVSLLECEQVSRKLKEELERISPDLDFTLKVSSAGAERKLHLPEDIDRFRGIPVRLVFRSGESEKNQEGIFRIVNRDGDQVFLEKFQKGKKSAVKKQTTLNLKDILKGNLYVSI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_ANAD2
Sequence: MSESAERKSILDVVGIQKLLPHRPPFLLVDRVVEFEAHRRLVALKGVTMNEPFFQGHFPAQPVMPGVLILEALAQAAALLATMSLQPDEVKDKITYLMGIDGARFRRPVVPGDRLELEVEVTKQKGAVWKQTGVARVDGQVVAEAEFMAMLADRER
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLRB1_MOUSE
Sequence: MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
What are the official names of this protein?
Dynein light chain roadblock-type 1, Dynein light chain 2A, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the GAMAD family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TRMB_MYCPA
Sequence: MGHHGQMHAQHGVTMPADSPIGQPDRSEQRYFPATAFRTRRSTLSDAQRQTWDRRWPELGLSVGPAEDPDRPGPPLDTDAWFGRKAPVVLEIGCGNGTSTLAMAKEEPGVDVIAVEVYRRGLAQLLCAIDRDNVTNIRLIRGNALDVLQRLIAPASLTGVRVFFPDPWPKARHHKRRFLQPGTVGLIADRLLPGGVLHVATDHAGYAEHIADVGAGEPRLRPANPDSPLPISVARPTTKYETKAQDAGSAVTEFIWLRR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TYSY_ECO8A
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_ECOSE
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC85C_MOUSE
Sequence: MAKPPAVAAAAAAAASEELSQVPDEELLRWSKEELARRLRRAEGEKVGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERAALAAAGGAGGGGGGAGSRSSIDSQASLSGPLAGSAAGSGARDVGDGSSTSSAGSGGSPDHHHHVPAALLPPGPHKVPDGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRPLETKVKLLDGDKLPPQQAGSGEFRTLRKGFSPYHSESQLASLPPSYQEVLQNGPACPVPELPSPPSTVYSSAGQKPEAVVHAMKVLEVHENLDRQLQDSCEEDLSEKEKAIVREMCNVVWRKLGDAASTKPSIRQHLSGNQFKGPL
What is the function of this protein?
May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).  May play an important role in cortical development, especially in the maintenance of radial glia (PubMed:22056358).
What are the official names of this protein?
Coiled-coil domain-containing protein 85C.
What is the protein family that this protein belongs to?
Belongs to the CCDC85 family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell junction, adherens junction. Note=Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain. Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall.
Protein: TOL7_ARATH
Sequence: MRPSCASSSSSSASPSLRLSSVTVAVDKATSELLRTPDWTIIIAICDSLNSNRWQCKDAIKAVKRRLQHKSSRVQLLTLTLLEAMLKNCGDFVHSHIAEKHLLEDMVKLVRKKGDFEVRNKLLILLDTWNEAFSGVACKHPHYNWAYQELKRCGVKFPQRSKEAPLMLEPPPPVTQSSSSSSMNLMSIGSFRRLDETMATEIESLSLSSLESMRNVMDLVNDMVQAVNPSDKSALKDELIVDLVEQCRSNQKKLIQMLTTTADEDVLARGLELNDSLQVVLARHDAIASGVSLPLLLQAPEPRETSSSLKTCGAAALESADSESSSSSSSSESETDEVEDVKDDFIQLAKRHALLNALHSDEEEETLLLGNDNEKTAEAEAKTQCKDLALFDTTTTTTTKSEQDIIELLSLTLSTTALPSPQTQPQTQHPSFFADDNILMNSYVVPWAQSQEEPQVPKMTQFAPSGPQFQPWPLQQQQPYSYGYPQPQWSGGQVNSNDTTFWSQGGNENMVFERNLQVSNSFPARATGTSGAATAATVDRQP
What is the function of this protein?
Might contribute to the loading of the ESCRT machinery.
What are the official names of this protein?
TOM1-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: Y1057_SULIN
Sequence: MSAPTSYNDEELEELLRRKAAQEQKRLEEERKRKAELESQKESILRVILTPEARQRLTNIKLVKPEFAESLENQLIALAQSGRIKVPITDEELKQILEQISEQNRRDFKIQIRERGWK
What are the official names of this protein?
DNA-binding protein YN1551_1057.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.