PharMolix/UniProtQA huggingface dataset:
Protein: OPSO_LIMPO
Sequence: MANQLSYSSLGWPYQPNASVVDTMPKEMLYMIHEHWYAFPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFMMPTMASNCFAETWILGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAAPLTHKKATLLLLFVWIWSGGWTILPFFGWSRYVPEGNLTSCTVDYLTKDWSSASYVIIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLRANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIIAWAGVFSSGTRLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLACGSGESGSDVKSEASATMTMEEKPKSPEA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Ocellar opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AT5F1_MOUSE
Sequence: MLSRVVLSAAATAAPCLKNAAALGPGVLQATRAFHTGQPRLAPLPPLPEYGGKVRLGLIPEEFFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFSTISVVGLIVYVIKKYGASFGEFIDKLNEEKIAQLEEVKQSSMKQIQDAIDMEKAQQALVQKRHYLFDVQRNNIALALEVTYRERLHKAYKEVKNRLDYHISVQNMMRRKEEEHMIDWVEKHVVKSISVQQEKETIAKCIEDLKLLAKKAQAQPIM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase peripheral stalk-membrane subunit b, ATP synthase subunit b, ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: US31_HCMVA
Sequence: MSLLEREESWRRVVDYSHNLWCTCGNWQSHVEIQDEEPNCEQPEPAHWLEYVAVQWQARVRDSHDRWCLCNAWRDHALRGRWGTAYSSGSSASSSGFVAESKFTWWKRLRHSTRRWLFRRRRARYTPSNCGESSTSSGQSSGDESNCSLRTHGVYTRGEQH
What are the official names of this protein?
Uncharacterized protein HHRF6.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US1 family.
Protein: CND3_YEAST
Sequence: MQDPDGIDINTKIFNSVAEVFQKAQGSYAGHRKHIAVLKKIQSKAVEQGYEDAFNFWFDKLVTKILPLKKNEIIGDRIVKLVAAFIASLERELILAKKQNYKLTNDEEGIFSRFVDQFIRHVLRGVESPDKNVRFRVLQLLAVIMDNIGEIDESLFNLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHLTELSDNEENFEATRTLVASIQNDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLVYSRILKSMGRKCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELLEKLDVSRSSVCVKAIEALFQSRPDILSKIKFPESIWKDFTVEIAFLFRAIYLYCLDNNITEMLEENFPEASKLSEHLNHYILLRYHHNDISNDSQSHFDYNTLEFIIEQLSIAAERYDYSDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSINEKDFVTMAIEIINDIRDDDIEKQEQEEKIKSKKINRRNETSVDEEDENGTHNDEVNEDEEDDNISSFHSAVENLVQGNGNVSESDIINNLPPEKEASSATIVLCLTRSSYMLELVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKLAIDNMYILGMCVSKGNASLKYIALQVIVDIFSVHGNTVVDGEGKVDSISLHKIFYKVLKNNGLPECQVIAAEGLCKLFLADVFTDDDLFETLVLSYFSPINSSNEALVQAFAFCIPVYCFSHPAHQQRMSRTAADILLRLCVLWDDLQSSVIPEVDREAMLKPNIIFQQLLFWTDPRNLVNQTGSTKKDTVQLTFLIDVLKIYAQIEKKEIKKMIITNINAIFLSSEQDYSTLKELLEYSDDIAENDNLDNVSKNALDKLRNNLNSLIEEINERSETQTKDENNTANDQYSSILGNSFNKSSNDTIEHAADITDGNNTELTKTTVNISAVDNTTEQSNSRKRTRSEAEQIDTSKNLENMSIQDTSTVAKNVSFVLPDEKSDAMSIDEEDKDSESFSEVC
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.  The condensin complex probably also plays a role during interphase.
What are the official names of this protein?
Condensin complex subunit 3, CAPG homolog.
What is the protein family that this protein belongs to?
Belongs to the CND3 (condensin subunit 3) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: SPT16_ASPOR
Sequence: MAEEIVIDKSAFFNRLSSFFAAWKADKRPGHAVFGGVGSIVILMGKTDEANSFQKNNAMHFWLLGYEFPATLMVFTTDMMYVVTTAKKGEDWPNTDSAYLSANTGLLNVAKHLEPLKGGKIPVEILVTSKDPDEKSRSFEKCLEVIKNAGKRVGVLPKDTAAGPFAEDWKRAFANITQDVEEVDISPALSSAAFSVKDTDELVAIRNASRACSGLMSEYFVDEMSRLLDEEKQMTHKALSMRIDAKIDDAKFFKKLAKLPAEFDPQQIDWAYGPVIQSGGKYDLRLTATSDNSHLQAGIIVAGFGIRYKTYSSIIARTYLVDPSKSQEANYAFLLNLHDTVMKDVRDGTMAKDLFNKAIGLVRAKKPELESHFVKSVGAGIGIELRDSNMVLNGKNNKILKSGMTLSITVGLTDVEELESKDKNTAVYSMIITDTVRVGENGPHIFTKDAGIDMDSVSFYFGDEEEPQKPAKEKKEVKSNAMTSRNVTRTKLRAERPTQVNEGAEARRREHQKELATKKTKEGLDRFAGTTGDDNGVTQKKFKRFESYKRDNQLPTKVKDLTIYVDHKASTVIVPIMGRPVPFHINTIKNASKSDEGEYAYLRINFLSPGQGVGRKDDQPFEDISAHFLRNLTLRSKDNERLAQVAQDITELRKNALRREQEKKEMEDVVEQDKLVEIRNRRPVRLPDVYLRPPLDGKRVPGEVEIHQNGLRYMSPFRNEHVDVLFSNVKHLFFQPCAHELIVLIHVHLKTPIMIGKRKTRDVQFYREATEMQFDETGNRRRKHRYGDEEEFEAEQEERRRRAALDREFKAFAEKIADAGKDEGVDVDIPFREIGFTGVPNRSNVLIQPTTDALVQLTEPPFLVITLNEIEIAHLERVQFGLKNFDLVFVFKDFHRPPVHVNTIPVESLEGVKDWLDSVDIAFTEGPLNLNWTTIMKTVVSDPYGFFADGGWSFLAAESDSEGGASDEEESAFELSESELAAADESSEDDSEFDDDASAEASEDFSADEDSGEDWDELERKAKKKDRESGLDDEERGKKRKR
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit spt16, Facilitates chromatin transcription complex subunit spt16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SURE_SYNR3
Sequence: MASPLKILISNDDGVFAEGIKALAHEAARRGHSVTVVCPDQERSATGHGLTLQSPIRAEQADGLFADGIRAWACTGTPSDCVKLALGKLLEAPPDLVLSGINHGPNLGSDVIYSGTVAAAMEGTLEGLPALAVSSACFDWRQFDGAAVQAMDVAESALAGGWPEGLLLNLNVPAVPPDRIGPVRWCRPGVRRYVDQFDERFDPRGRSYYWLAGEVVNDFEAAGTGPKDWPTDVAQVQGGGVALTPLQPELFWRGALPPLPIAGVSAAPDAAAARG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_CAMJJ
Sequence: MKLSHLDEKNHPKMVDVGDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIAAIMGAKKTSEIIPMCHPLMLSKVETDIMEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RL14_STRMU
Sequence: MIQSESRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIRDDKTPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ITM2B_MOUSE
Sequence: MVKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGLKYIKDDVILNEPSADAPAARYQTIEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPKNLLELLINIKAGTYLPQSYLIHEHMVITDRIENVDNLGFFIYRLCHDKETYKLQRRETIRGIQKREASNCFTIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Protein E25B, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: MASU1_HUMAN
Sequence: MGPGGRVARLLAPLMWRRAVSSVAGSAVGAEPGLRLLAVQRLPVGAAFCRACQTPNFVRGLHSEPGLEERAEGTVNEGRPESDAADHTGPKFDIDMMVSLLRQENARDICVIQVPPEMRYTDYFVIVSGTSTRHLHAMAFYVVKMYKHLKCKRDPHVKIEGKDTDDWLCVDFGSMVIHLMLPETREIYELEKLWTLRSYDDQLAQIAPETVPEDFILGIEDDTSSVTPVELKCE
What is the function of this protein?
Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548).  May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable).  Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable).  Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable).  May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548).  May function as a ribosomal silencing factor (Probable).
What are the official names of this protein?
Mitochondrial assembly of ribosomal large subunit protein 1.
What is the protein family that this protein belongs to?
Belongs to the Iojap/RsfS family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Note=Colocalizes with MRPL12 and/or MRPL14.
Protein: INPF_EMENI
Sequence: MRILFFHGHTQTGPVFERKTVRLREHIQRAYPGSTFFFPTGPIAYKVSDRLDYLSEIQRERSDNFKDPDLIETHAWFRLFEDDPPRGLLESLDIAAEILRVEGPFDGVICFSQGSVVGSMMASLLEGPRRRQRFDEYAASFPGAVRYPKSYKNINHPPLKFGITYGAYMGTSPVFNAFYSEPLIETPFLHFMGEFDPVVPSEMVAAVDKAQIGGSRRRKVMHPGAHAIPVGDRYHEAVVDFIRSACETSPTYFDLPSDEVPLLSYNDTPEQTPFQTPLLTPSLSSAVSTTSIPSSEATILATRRLDQWEKSRSPRSNIRPRSTRRTVFSGRRSTSSSAESSAASQHSDHFEATRTPTSSTSTVQMIEPTVNKEPNLAVRVVEDDTIVSGSEYEGEGWQELLLSDLLNEMLRRHGRPGRFYFVPDGEGGRLENGMRLN
What is the function of this protein?
Esterase; part of the inp gene cluster that mediates the biosynthesis of fellutamide B, a mycotoxin that acts as a proteasome inhibitor (PubMed:20952652, PubMed:27294372).  In the first step of fellutabmide B biosynthesis inpC activates 3-hydroxydodecanoic acid to generate 3-hydroxydodecanoyl-AMP that is then loaded onto the T0 domain of inpB (PubMed:27294372).  The 3-hydroxydodecanoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-Asn and L-Gln by the two CAT modules of inpB (PubMed:27294372).  The linear lipodipeptide from inpB is then transferred onto inpA for the addition of the third amino acid, L-Leu (PubMed:27294372).  Reductive releasing of the lipotripeptide by the TE domain of inpA produces (2S)-fellutamide B (PubMed:27294372).  InpF might be involved in the release and transfer of the lipodipeptide from inpB to inpA (PubMed:27294372).  The inp cluster-encoded proteasome subunit inpE confers resistance to internally produced fellutamides (PubMed:27294372).  The MFS efflux transporter inpD may contribute to fellutamide resistance as well (PubMed:27294372).
What are the official names of this protein?
Esterase inpF, Fellutamide B biosynthesis cluster protein F, Inp cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: GPDA_VIBCH
Sequence: MSETQNHNSYGKPVEMTVIGAGSYGTSLAISLARNGANIVLWGHDAEHMARLDADRANHEFLPGIAFPDTLIVETDLQKAVQASRDLLVVVPSHVFGIVLKSLQPHLRADSRICWATKGLEPETGRLLQDVAHDVLGDSYPLAVLSGPTFAKELAMGMPTAISVASPDAQFVRDLQEKIHCSKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGKDVDTAQTDIGQVVEGYRNTKEVWMLAKRMGVEMPIVEQIYQVLYQGKDARLAAQDLLARDKKMER
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_THET2
Sequence: MNGSADAGPRPRKYVFITGGVVSSLGKGILTSSLGALLRARGYRVTAIKIDPYVNVDAGTMRPYEHGEVFVTADGAETDLDIGHYERFLDMDLSRGNNLTTGQVYLSVIQKERRGEYLSQTVQVIPHITDEIKERIRKVAEEQKAEIVVVEVGGTVGDIESLPFLEAIRQFRFDEGEGNTLYLHLTLVPYLETSEEFKTKPTQHSVATLRGVGIQPDILVLRSARPVPEEVRRKVALFTNVRPGHVFSSPTVEHLYEVPLLLEEQGLGRAVERALGLEAVIPNLAFWQEAVRVLKHPERTVKIAIAGKYVKMPDAYLSLLEALRHAGIKNRARVEVKWVDAESLEAADLDEAFRDVSGILVPGGFGVRGIEGKVRAAQYARERKIPYLGICLGLQIAVIEFARNVAGLKGANSTEFDPYTPHPVIDLMPEQLEVEGLGGTMRLGDWPMRIKPGTLLHRLYGKEEVLERHRHRYEVNPLYVDGLERAGLVVSATTPGMRGRGAGLVEAIELKDHPFFLGLQSHPEFKSRPMRPSPPFVGFVEAALAYQERA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LYS4_USTMA
Sequence: MGASNLLRFGAVTRISTPLLSRRSLATHAAVNPASGTYNLVEKIVQKYAVDLSPGSHVKSGDYVSIRPGTVMTHDNTGPVISKFGSIGATSIYNPDQVVFALDHDVQNKSAKNLEKYSKIESFARKHGIDFYPAGRGIGHQVLVEEGYAFPQTLAVASDSHSNMYGGVGCLGTPIVRTDAAAIWATGQTWWQIPEVVKVELKGELPKGVTGKDVIVALCGYFNKDQVLNAAIEFHGSGLSSLSVEERLAIANMTTEWGALAGLFPTDDVTLSWYEKQIRKRDKLEFQIGSSPSPSNSHPRLNMNRLDELSRTLLRPDSGAVYSKHLTLDLATLVPHVSGPNSVKVSTPLDELTSQNIAINKAYLVSCVNSRASDLKAAADVIRGKKVAPGVEFYVAAASSVVQREAEEAGDWGALMAAGAKPLPAGCGPCIGLGVGLLEDGEVGISATNRNYKGRMGSPNAQAYLASPAVVAASAIEGKICGPSDLDVSLLPPSKGLKYSISTAANAAPADASSTDASAGGVEILDSFPTAFSGPLIFAPQDNLNTDGIYPGKYTYQDDITPEKQAEVVMENYDASFASTVAGLRASSSSSSSTKQGPILIGGYNFGTGSSREQAATALKYAGIPLVLAGSFGDIFQRNAINNGLICLESHQLVQDLTRLYLENEGGVRNSKAILLDESKVHIDSSTGSINLSFKGPDGAKIERTYTAKPAGIGRSVQEIYTAGGLEKWVKQRI
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TCF15_CHICK
Sequence: MAFTMLRPMAARVLYPDIGMLSEDEENRSESDTSDQSYGCCEGAEARRKVPRKTGPMVMVKQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGEGCEDGQPCFSAIYGAKGDLDGRQPRSICTFCLSNQRKGGGRRDLGGNCLKVRGVTPLRVARR
What is the function of this protein?
Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency.  Essential for the mesenchymal to epithelial transition associated with somite formation.  Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and skeletal muscles.  Also plays a key role in regulation of stem cell pluripotency.  Promotes pluripotency exit of embryonic stem cells (ESCs) by priming ESCs for differentiation.  Acts as a key regulator of self-renewal of hematopoietic stem cells (HSCs) by mediating HSCs quiescence and long-term self-renewal.  Acts by forming a heterodimer with another helix-loop-helix (bHLH) protein, that binds DNA on E-box motifs (5'-CANNTG-3') and activates transcription of target genes.
What are the official names of this protein?
Transcription factor 15, TCF-15, Paraxis, Protein bHLH-EC2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CKR1A_CONRO
Sequence: MQLYTYLYLLVPLVTFHLILGTGTLDHGGALTERRSTDATALKPEPVLQKSAARSTDDNGKDRLTQMKRILKKRGNNPRADEEYLKFIEEQRKQGKLDPTKFP
What is the function of this protein?
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.  This toxin has the highest potency for the NR2B/GRIN2B subunit (IC(50)=0. 11 uM), followed by NR2D/GRIN2D (IC(50)=0. 48 uM), NR2A/GRIN2A (IC(50)=2. 1 uM), and NR2C/GRIN2C (IC(50)=6. 1 uM) subunits when tested on rat receptors.
What are the official names of this protein?
Conantokin R1-A, Con R1-A, ConRl-A.
What is the protein family that this protein belongs to?
Belongs to the conotoxin B superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TTCA_XANCP
Sequence: MTAVLPLPLPLADPAPRTPRLQREPLRLAKRLRHAVGQAIADFGMIAPGDKVMVCLSGGKDSYTLLDMLLQLQRSAPVPFTLVAVNLDQKQPDFPADVLPTYLRAQQVPFDIIEQDTYSVVSRVIPQGKTMCSLCSRLRRGALYAYAQAHGVTKIALGHHRDDIVATFFMNLFHHARLAAMAPKLRSDDGAHVVIRPLAYVREADIAAYAQARHFPIIPCNLCGSQENLQRQQVGRMLQQWDREQPGRVDQIARALGDVRPEQLADRTLFDFPGLGGGADAPLPDAAGWLAGSAAEHARD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP60_SCHPO
Sequence: MSSGPIRTLHKGKAARNRTPYDRIAASKDGNHSNGPQTPSKSIFQRAKEWLTPSSWKKAISIFSSPVVNKHEDSFDSKTDEEYLQNVSTTTEDVSMLINTPVTEKYEQEHRDTSAQATPSIVEQSPNQMLANFFSKKGKTPLNEIEKEGIISILNKSASPSSSVISPAASLNRFQTPRAAAISKRESGVSSEPRARTSSLTPGNTPNSAKQWSAFRSTFSPLREQDQLSTISPNSLLPAQRLSYYGPTLSTPYNRRLRHKRHSTTPISLSNSIAPSLSFQPKKARYESANVSFNDTSFTNVPTSSPLHQSTTANHPEKTPSRAAASLLSILDSKEKNTPSITAKAGSPQSAPSKASYISPYARPGITTSRRRHDQIRPSSEKSEPEKKEPSAFETLEKSSNVQTYKPSLMPEFLEKASTHGSFAKQKEGEQTSLSEKTALSEPENKTPVFSFKAPSATTDKPSPPVSSIFSFNAPSAASTKPSPAVSSTFSFNAPTTTPSATSFSIINKEKPARSPNETIDVDLEEEGSGISAEVEVANEGEDLQKNATEVKASTSEKPVFRFEAVTDEKNSEVSSSNQASSSTMISQPNTGFSFGSFNKPAGQEEKPQQRSLFSASFTTQKPELPAAKIEPEVQMTNVAIDQRSFEQAEKSPISVSESTSLVEVEKPSAEGTNEHKQDATMTLEKTDKQGSLEEEPFPKFSFTVLPKENGENLSTMESTQELPKFSFSVLKEEKN
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (By similarity).
What are the official names of this protein?
Nucleoporin nup60, Nuclear pore protein nup60.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
Protein: YRK_CHICK
Sequence: MGCVHCKEKISGKGQGGSGTGTPAHPPSQYDPDPTQLSGAFTHIPDFNNFHAAAVSPPVPFSGPGFYPCNTLQAHSSITGGGVTLFIALYDYEARTEDDLSFQKGEKFHIINNTEGDWWEARSLSSGATGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLCHGNCRGTFLIRESETTKGAYSLSIRDWDEAKGDHVKHYKIRKLDSGGYYITTRAQFDTIQQLVQHYIERAAGLCCRLAVPCPKGTPKLADLSVKTKDVWEIPRESLQLLQKLGNGQFGEVWMGTWNGTTKVAVKTLKPGTMSPEAFLEEAQIMKRLRHDKLVQLYAVVSEEPIYIVTEFMSQGSLLDFLKDGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALFGKFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMQCPGGCPPSLHDVMVQCWKREPEERPTFEYLQSFLEDYFTATEPQYQPGDNQ
What is the function of this protein?
May participate in signaling pathways.
What are the official names of this protein?
Proto-oncogene tyrosine-protein kinase Yrk, Yes-related kinase, p60-Yrk.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: RPOT3_NICSY
Sequence: MASTASYSPSPTSQWRTQKLPKRFNFYVIHNQEFGKLSQSSSLPTSSFPKTLKLPVIQMPINNNIQSQTTVCVSTDENLEELVNLQKIANGVLTKESNKRVFIQDPPWVSSLFMNSLFVRAKQVQGVRREFREIERRRRYAMLRRRQIKAETEAWEQMVEEYRELEREMCEKKLAPNLPYVKKLLLGWFEPLRQAIEKEQNAETTVKHRAAFAPHIDSLPADKMAVIVMHKLMGLLMMGGKEERCVQVVQAAVQIGMAVENEVRIHNFLEKTKKLQKHMTGAQSQEDMSRETMILRKRVKSLIKRNRVVEVRKLMKSEEPESWGRDTQAKLGCRLLELLTETAYVQPPVDQSADTPPDIRPAFRHVFRIATRDPGKSIVKKYGVIECDPLVVAGVDRTVKQMMIPYVPMLVPPKKWRGYDKGGYLFLPSYLMRTHGSRRQQDAVRSVPTKQMQQVYEALDTLGSTKWRVNKRILSVVESIWAGGGNIAGLVDRKDVPIPELHSDDIMEVKKWKWRVRKSKKINQELHSQRCDTELKLSVARKLKDEEGFYYPHNLDFRGRAYPMHPHLNHLSSDLCRGILEFAEGRPLGKSGLRWLKIHLASLYAGGIEKLCYDARLAFVENHIDDILDSANNPLNGNRWWLNAEDPFQCLAACINLSEALKSSSPHTVFSHLPIHQDGSCNGLQHYAALGRDSMEAAAVNLVAGDKPADVYTEIALRVDHIIRGDSIKDPATDPNALLAKLLIDQVDRKLVKQTVMTSVYGVTYVGAREQIKRRLEEKGLIDDDRLLFTASCYAAKVTLAALGELFQAARGTMTWLGDCAKVIASENQPVRWTTPLGLPVVQPYFKTQRHVIRTSLQVLALQREGDTVEVRKQRTAFPPNFVHSLDGSHMMMTAVACRDAGLQFAGVHDSFWTHACDVDQMNRILREKFVELYSMPILEDLLESFQNSYPALTFPPLPKRGDFDLVEVLESPYFFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase 3, chloroplastic, NsRpoT-C, T7 bacteriophage-type single subunit RNA polymerase 3.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.