PharMolix/UniProtQA huggingface dataset:
Protein: SC5A8_DANRE
Sequence: MPGSGGPVATFSVWDYVVFAGLILVAAGIGLFQSFRGRKEASSDEFLLGGRQMTAVPVALSLTASFMSGITVIGTPAEAYLYGTPFWLFFISYAIMSTISAEIFVPLFYRLNITSTYEYLEMRYNKLIRVIGTSMYIIQTALYTGMVIFAPALALNQITGLDLWGVLVATGAVCIIYCTLGGLKAVIWTDVFQMIIMLGGFVAVIARGAVLQGGLGRVWNDSFYGGRLETFSFDPDPLRRHSFWTIVVGGSLMWASMYSINQSQVQRYISCRTMTHAKLSLYVNMVGLWVTVSLAMMSGLTMYSIYKDCDPFTNKDVGATDQLLPYLVMDILADFPGLPGLFVAAAYSGTLSTVSSSINALVAVTVEDFMKPAWPSLTERQLSWINMGMSVFYGAVCIGMAGVASMMGNILQAALSIFGMISGPLLGLYMLGMFFRCANSTGGLAGLASGLAITLWVGIGAQLYPPLPEKTLRLPLSVEGCVALNTSETTTMTPFSTVLQTTTPQPRPALADNWYSLSYLYFSPVGIVVTMIIALIVSAISGGCKQKKVRPELFISKSDLICFRCKKSDSEVSDLIETKPKDNQGLDSPVFYDNEIVLKEKDQQEKITKL
What is the function of this protein?
Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1.  Catalyzes passive carrier mediated diffusion of iodide.  Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane.
What are the official names of this protein?
Sodium-coupled monocarboxylate transporter 1, Electrogenic sodium monocarboxylate cotransporter, zSMCTe, Sodium solute symporter family 5 member 8 protein, Solute carrier family 5 member 8.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RL32_AGRVS
Sequence: MAVPKRKTSPSKRGMRRSADGLKAPTYVEDKNSGELRRPHHIDLKTGMYRGRQVLTPKESA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MDH_EHRCJ
Sequence: MIKRKKIALIGAGNIGGMIAYLIRLKNLGDVVLLDVNDGIAKGKALDMAESSPVGKYNGEILGTNNYADIEGADAIVVTAGITRKPGMSREDLINTNVNIIKEVADNIGKYAPNAFVVVVTNPLDVMVFAMHKYSKLSSNMVVGMAGILDSARFSYFIAKELNVSVDNVNSLVLGGHGDLMLPLVKYSSVAGISIADLIKIDLITQDKVDAIIERTRKGGEEIVSLLKIGSAYYAPAESALLMIDSYLNDRRLILPCSVYLKGEYGVSNLFVGVPVIIGRNGVEKIIELELTEQEKNIFDNSVKLIKNLVSNV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: E4PD_SHEPW
Sequence: MIRVAINGYGRIGRSILRAVYESAKRDRIQIVAINELAKPEAMLHLTQYDTTHGRFHTQVKLDEQHMIIGDDAIKLLHEPNPANLPWQEMDIDIVFEATGVINDRQACEAHIEAGARQVLISHPSSSDVDATIVYGVNQDLLKAEHTIVSNASCTTNCIVPVIDVLDRHFQVKSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPHMKDKFEAISVRVPTINVTAIDLSVTLDKRVDIEQVNRVLKQATEGSFSGVVGYTNEPLVSCDFNHDPRSSIVDGTQTRVSDGHLVKLLLWCDNEWGFANRMLDTSLEMIKARRA
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHA1_STAA8
Sequence: MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTILISGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: RLMN_STACT
Sequence: MITTQKKKKNRFLPDFDKQSIYSLRYEEMQDWLVEHGQQKFRAKQIFQWLYEKRVDSIDEMTNLSKDLREVLKDNFTMTTLETVVKQESRDGTIKFLFELQDGYTIETVLMRHEYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKVLDATDERVSQIVIMGIGEPFENYDEMMDFLKIVNYDNGLNIGARHITVSTSGIIPRIYDFAEEDIQINFAVSLHAANDEIRSKLMPINRAYSIDKLMEAIQYYQEKTNRRITFEYGLFGGVNDQLTHARELAHLIQNLNCHVNLIPVNHVPERNYVKTPKEDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  Confers resistance to some classes of antibiotics.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIN2_HUMAN
Sequence: MTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDGGYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVHKSTKMQKKVLSLRLPCEFGAPLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKSEAQLEELAQMGLNFWSSPADSKPPNLPPPHRPLSSDGVCPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSGGLKRPSTRTPNANGTERTRSPPPRPPPPAINSLHTSPRLARTETQTSMPETVNHNKHGNVALPGTKPTPIPPPRLKKQASFLEAEGGAKTLSGGRPGAGPELELGTAGSPGGAPPEAAPGDCTRAPPPSSESRPPCHGGRQRLSDMSISTSSSDSLEFDRSMPLFGYEADTNSSLEDYEGESDQETMAPPIKSKKKRSSSFVLPKLVKSQLQKVSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLQENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHMADGSWKQLKENLQLVRQRNPQELGVFAPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSETRDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQICAEKFKVGDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGIIFQNGEEDLTTS
What is the function of this protein?
Ras effector protein.  May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway.  May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP.
What are the official names of this protein?
Ras and Rab interactor 2, Ras association domain family 4, Ras inhibitor JC265, Ras interaction/interference protein 2.
What is the protein family that this protein belongs to?
Belongs to the RIN (Ras interaction/interference) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_UREPA
Sequence: MKILLIGPPGSGKGSVSELLTKNNTLKHVSTGNLFRAILKEDSELARKIKEINVSGGKLVPDEITNQVAKSAIDELIKNEQSFILDGYPRTINQALALEQYCNLDYIFYLDIDHQELMKRLTGRWMCPKCAGIYNIHFKKPQVHGLCDNDQATLYQRADDHADAVSIRLDEYDKLTLPLIKHYETNPRFIKINANQPIEDVYKNINNYLKQNK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1A_XENLA
Sequence: MGIHGLAKLIADVAPAAIKEHDIKSYFGRKVAVDASMCIYQFLIAVRQDGNTLQNEEGETTSHLMGMFYRTIRMVEHGIKPVYVFDGKPPQMKSGELAKRSERRAEAEKLLEAAEEAGEVENIEKFTKRLVKVTKQHNEECKKLLTLMGIPYVDAPCEAEATCAALVKAGKVYAAATEDMDALTFGTPVLLRHLTASEAKKLPIQEFHLNRVIQDIGITHEQFVDLCILLGSDYCETIRGIGPKRAIDLIRQHKTIDEIIDNIDLKKYPVPENWLHKEAKHLFLEPEVVDTDITELKWIEPDEEGLVAFMCGEKQFSEDRIRNGAKKLAKNRQGSTQGRLDDFFKVTGSVSSTKRKEAESKGSAKKKAKTGGTPAGKFKRGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-A, FEN-1-A, Flap structure-specific endonuclease 1-A, xFEN-1a.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: OLSB_AGRFC
Sequence: MVAEIFNHDICENNVVISPRSETAQDNEGLFGRIGTLETRLARNEREIDAAQSVRYRVFVEEMKARLPAEAMRRKRDFDAWDSVCDHLLVLDKSIEGDSEDQIVGTYRLLRQETALANNGFYSASEFDIAGLVARHPGKRFMELGRSCVLPEYRTKRTVELLWQGNWAYAVKHRMDAMIGCASFPGVQPEAHALALSFLHHNCLAKGEWEAVALPELYHEMDLVPVEALNTRKALNAMPPLIKGYMRLGAMFGSGAVVDHAFNTTDVLVVLPVSSIAGRYISYYGGEAERING
What is the function of this protein?
Catalyzes the first step in the biosynthesis of ornithine lipids, which are phosphorus-free membrane lipids.  Catalyzes the 3-hydroxyacyl-acyl carrier protein-dependent acylation of ornithine to form lyso-ornithine lipid (LOL).
What are the official names of this protein?
L-ornithine N(alpha)-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. OlsB subfamily.
Protein: RECR_DESAL
Sequence: MSFYPPSLVNLIKQLSKLPGIGEKTAERLALHILRGSVKDAQALAESISEAKETVRLCSVCYGLADSDPCHICRDATRDQDVVCVVEQGTDMVALEKSGAFKGRYHVLQGCLSPMNGVGPDNLRIRELVERLKKEKIKEVVVATGTSVEGESTANYLRQVLEGSGVKITRIASGVPIGGDLKYTDALTLKRALDSRHCL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MIC60_SORMK
Sequence: MLRTSLRSVRALGSRPSAAVAGRQWQATVVRRAAVSGQRFFADDKKPVVPEPAQPAVLPASETLTAPSTPPPASPQVEPTSTIAPETTPLTPPAPEATVIPPVAEEPVVPPTLPTPRKKKGFFRRLRNFLLSLTILGAIAFGGGVYYSRINDAFHDFFTEYIPYGEQAVLYLEELDFKKRFPDVVSRVTGRPRDSGEQVKVPAQSGASWRVADGGEPAGRQSSSIKKAAVAAKDAVTKSEPAVVAGANKDTAELPKAESTTTVTPVEPVPVAVAVADPATAVAPADTAAAAAPAKKPFKAPEVDEPSRWPPASPIDPLKVNGATDPIVQDLVHMLNDIITVINHDNANEKYAPTIGKAKNELSKVAGRINEMKAKVEAEASKQVKARVDGFDKAANELVSRVESAMAAQEAAWRREFEEEMIRLKKSYDEKIHLIQDRERQIAEEKLNNRLLEQAIQLQRQFTDDIKKHVEEERDGRLGKLNELSSAVADLEKLTSGWNEVVDTNLRTQQLHVAVEAVRASLQDAHHPRPFIKELVALKEIAAEDPVVDAAISSINPTAYQRGISTSAELIDRFRRVATEVRKASLLPEDAGVASHASSYVLSKLMFKKEGLAAGDDVESILTRTQTYLEEGDLDNAAREINGLQGWAKTLSRDWLGEVRKVLEVQQALEVIQTEARLQSLRME
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: QUED_RICFE
Sequence: MIKCTRRIEFDAGHRIIGHQNKCQFLHGHRYVLEIAIAANKTDKLGMVIDFGLIKDVAKKWIDENFDHSLILHQDDKEMGQQIENCTGQKIYYMQNNPTAENIATHLKNEIFPKLFVGQNFFVSNLKLYETPNCFVEV
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Queuosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: SMP_SALTI
Sequence: MARAKLKFRLHRAVIVLFCLTLLVALMQGASWFSQNHQRQRNPQLEELARTLARQVTLNIAPLMRSETPDENRINAVLRQLTQESRILDAGVYDEQGDLITRAGESVNVRDRLALDGKKAGSYFNQQIVEPIQGKNGPLGYLRLTLDTHTLATEAKQVDNTTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEEREEKE
What are the official names of this protein?
Protein Smp.
What is the protein family that this protein belongs to?
Belongs to the Smp family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DCUP_GEOSL
Sequence: MNNRFLDACWGKPVDRTPVWLMRQAGRYLPEYMAVRSKCTFLELCKTPELAAEVTIQPIDILNVDAAILFSDILTPVEPMGLKLDFVPGPVFEHPVRTMADVEKLRIPNPEEDVPYVLDTIKILRRELAGRVPLIGFGGAPFTLACYMVEGKGSKDWANIKRMMYAAPDVYAALMDKVTMMDMEYLNAQIKAGAQAIQIFDTWGGVLSPTDYEKYVLPYTTKLINGLNRQNTPVIHFVKGAGTMLETVQKAGGDVMGLDWHVNLGKARDVLGQNMAVQGNLDPTVLYAPKEVIEAEVKRVLDENAGRPGHIFNLGHGILPTVPPENAIHMVECVHRLSQK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAA_SALNS
Sequence: MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAPQISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALEAQGDRVVVNLASEEYFKSVKPKKLNAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRFIIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: MENE_BACSU
Sequence: MLTEQPNWLMQRAQLTPERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGLSALFKSVIYGMTVVLHQRFSVSDVLHSINRHEVTMISAVQTMLASLLEETNRCPESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPEFSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLDNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKWGKVPHAYLVLHKPVSAGELTDYCKERLAKYKIPAKFFVLDRLPRNASNKLLRNQLKDARKGELL
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: RS16_STRA3
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVAENQVTIKEERVLEWLSKGAQPSDTVRNLLSKAGVMTKFHDQKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: O6C68_HUMAN
Sequence: MRKHTAITTFILLGLTEDPQLQVLLFMFLFITYMLSVTGKLTIIALTMLDPHLKTPMYFFLQNLSFLEISFTATCVPRFLYSISTGNKIITYNACVIQLFFADLFGVTEFFLLATMSYDRYVAICKPLHYMAIMSNKVCKTMVICCWMAALMIILPPLSLGFHLEFCDSNVINHFGCDALPILKIPCSDTSLIEQMVVASAVLTFIITLVCVVLSYTYIIRTILKFPSVQQKKKAFSTCSSHITVVSITYGSCIFIYIKPSAKEEVNINKGVSVLISSISPMLNSFIYTLRNEQVKQAFHDSLKKIAFRLKK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6C68.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_RICAE
Sequence: MKVIFMGTPEFAVPALKKLITHHEVKAVFTQQPKAKGRGLNLAKSPIHQLAFEHQIPVYTPSTLRNDEIINLINKVNADIIVVIAYGFIVPKAILEAKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDTGLDTGDILMKEDFDLEERITLEELHNKCANLGAELLIKTLANIDNIVPITQPSDGVTYAHKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKIIKILEAEYLNADHHFTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CLPS_LEGPA
Sequence: MSKQNLEEIIQTGIADTELSTEISTAIKRPRKYKVLLLNDDYTPMDFVVEVLKHFFHLNEEVAIQVMLQVHFQGKGVCGVFTRDIAETKVALVNEYARMNQHPLLSSMEPE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: NSP2_ROTW3
Sequence: MAELACFCYPHLENDSYRFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETPMFNKVAVLICEALNSIKVTQSDVASVLSKVVSVRHLENLVRRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEVVFQNAAFTMWKLTYLEHSLMPILDQNFIEYKITMNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNMIEFNLLDQRIIWQNWYAFTSSMKQGNTLEVCKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: WDL7_ARATH
Sequence: MAGEIQDPFSLSFQGNSIHSGSISFGRFEKEGLSWEKRSSFSHNRYLEEVDKCSKPGSVTEMKAHFEAHFKKKGIRFPASLESQTWGVHQTSNEPDDEAVHATESFEDYRSDGSFSEDTSQSNSVCNYSHEQEKCGQGKSQCEFDEESDHCVSYDEILVNSDEVIELDEEEGGGDHGRVADLVECENLGPPEMPQEIVIQDSALVEEAGSKLDEHASKKPSNSMETPSSSVNVKPIIPNDVRVTKASTKGHDVTPKAASRRTKGSSLSSNSKTNVDAKSQKELRPKKTIESQPKSSNKTETRPPIATNRCKTSTTSSKLEMSTGSTSFRFKCSERAEKRKEFYMKLEEKIHAKKTETNQVQAKTQQKAEAEIKQFRKSLNFKATPMPSFYNIGTRPVSHNKTEPSKVAQSRSRPATSASITNRAVTRVSYKHGFEEAEMVKVMVSNRKQSAAKDSDLQKGNLMAVEMKQQIGARRSRN
What is the function of this protein?
Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules.
What are the official names of this protein?
Protein WVD2-like 7.
What is the protein family that this protein belongs to?
Belongs to the TPX2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ESR2_ICTPU
Sequence: MSSSLSPTLQTVNGMDQDEPLPLFPSHYPTALGVDRGTVCIPSPYADNGHAEMSFCGPSAPENPAIAPPLSPSLFWSSHNPHAMPALPLHCPPALPYSEPHIHTAWVDTKPHTSGRHSSFLSRPKLFGKRPEDGDGDEALDDDDPSSSSSGAVVKRDMHFCVVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEMGMMKCGARRERCGYRASRRTAPMRDGSARPVGVRGQSQRLPHTPLHVSLSIPVSRASAESGFSGLSPEQLVYCILEAEPPQIYLKQQMKKPYTESTVMMSLTQLADKELVLMISWAKKIPGFVELSLAHQVQLLECCWLEVLMLGLMWRSIDHPGKLIFSLDLKLNRDEGNCVEGIMEIFDMLLAGSSRFRELKLQKEEYVCLKALILLNSSMYMTSSACEKDLESRTKLLRLLDAVTDALVWAISRTGLSTQQQSARLAHLLMLLSHIRHLSNKGMEHLSSMKRKNVVLLYDLLLEMLDANMAQSRHVSTSVCTDPVTPATSPNTPLPPQLHSPVAHHVTQVNESQCSQE
What is the function of this protein?
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_CLOBB
Sequence: MRIKPLGNRVVIKKLEAEEKTKSGIVLTGSAKEVPQEAEVVAVGPGSIVDGTKIEMEVKVGDKVLYSKYSGTEVKLDGEEYMILKQDDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPC2_ARATH
Sequence: MAWSIALLTPPFFGPGRHVQAKEYREPRGCVMKMSSLKAPVLRIQATEYREPRGRVKMMSSLQAPLLTIQSFSGLRAPSALDYLGRPSPGFLVKYKLAKSSGREKASRCVPKAMFERFTEKAIKVIMLSQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDSRVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLENLGADPSNIRTQVIRMVGENNEVTASVGGGSSGNSKMPTLEEYGTNLTKLAEEGKLDPVVGRQPQIERVVQILARRTKNNPCLIGEPGVGKTAIAEGLAQRIASGDVPETIEGKTVITLDMGLLVAGTKYRGEFEERLKKLMEEIRQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTIDEYRKHIEKDPALERRFQPVKVPEPTVEEAIQILQGLRERYEIHHKLRYTDEALVAAAQLSHQYISDRFLPDKAIDLIDEAGSRVRLRHAQLPEEARELEKQLRQITKEKNEAVRSQDFEMAGSHRDREIELKAEIANVLSRGKEVAKAENEAEEGGPTVTESDIQHIVATWTGIPVEKVSSDESSRLLQMEQTLHTRVIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKALAAYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTLVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDHDEKDSSYNRIKSLVTEELKQYFRPEFLNRLDEMIVFRQLTKLEVKEIADIMLKEVVARLEVKEIELQVTERFKERVVDEGFDPSYGARPLRRAIMRLLEDSMAEKMLSRDIKEGDSVIVDVDAEGSVVVLSGTTGRVGGFAAEEAMEDPIPIL
What is the function of this protein?
Molecular chaperone (PubMed:15304652, PubMed:21737456, PubMed:24599948).  May act as a suppressor of FtsH-mediated thylakoid membrane biogenesis and may enhance photoinhibition (PubMed:15304652).  Seems not involved in chloroplastic protein import (PubMed:15304652).  Probable component of the TIC-associated stromal import motor involved in inner membrane translocation (PubMed:17376159).  Has an ATPase activity, but no ADPase activity (PubMed:21737456).  Interacts with transit peptides with a positional preference (PubMed:21737456, PubMed:22545953).  Localization of the signal sequence at the N-terminal end of a protein seems mandatory for interaction to take place (PubMed:22545953).
What are the official names of this protein?
Chaperone protein ClpC2, chloroplastic, ATP-dependent Clp protease ATP-binding subunit ClpC homolog 2, AtClpC, Casein lytic proteinase C2.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast membrane.