PharMolix/UniProtQA huggingface dataset:
Protein: PSBE_OENBE
Sequence: MSGSTGGRSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDSLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MURG_LAWIP
Sequence: MKYRIAITTGGTGGHVYPALAVAEQFHDKADLFFIGSQYGPEAEMVKTFNIPFYGLPVRGVLGRKWKAFSALYSMIKAIVKARKILQKCMPDIVVGFGSYASFAPLVAAKLKRIPTAIHEQNVRPGLANRMLARLADRVFLSVPDTLHIFTKKSKVRYTGNPIRQSIVDLHYKFEDTKNSSTRHLLVLGGSLGAIAINSIVVDGLSRLFSNRIVIRHQTGVHDWERVKEGYALYGRTNSQVTPFIDDMAEAYQWSDLVLCRAGATTIAELAAVGKPSILIPFPYATHDHQTYNAQFLVRVGAAVLIPEKNVVEVDVIEKIIALFNDRVTLVNMALAAHKHGRIDAATCVANEIIDLLSANAMK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TATA1_AQUAE
Sequence: MHFPLPWQLILILLVILVIFGASKLPEVGKGLGEGIRNFKKALSGEEEEKGKEVKKEGE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA 1.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YAA7_ENCCU
Sequence: MTQESTMNDIYPLAALLIYATNQKVTKEKISSVFKFLGLESHPKICEFFEVDAVEIKKLLMSSTQEAAAPAGPQEPAEASGDAGKKEEVEEEEIEIDFGMF
What are the official names of this protein?
Uncharacterized protein ECU10_1070.
Protein: RHTA_ECOL6
Sequence: MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVTALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACWAIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILSTALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAASMGSTLTVRKESKIKELDIN
What is the function of this protein?
Involved in the efflux of threonine and homoserine.
What are the official names of this protein?
Threonine/homoserine exporter RhtA.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_SECDI
Sequence: VGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEEDQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPSYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVRARNEGRDLAREGNEIIREASKWSLELAAACEVWKEIKFNWQAVDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL3_SULIM
Sequence: MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIHSFSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLVATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPRWHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKKRPIFLREAVRPSYVFENAPKITYVNLLSKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LGMN_MACFA
Sequence: MVWKVAVFLSVTLGIGAVPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFVYFTDHGSTGILVFPNEDLHVKDLNETIYYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKHKASSPLSLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY
What is the function of this protein?
Has a strict specificity for hydrolysis of asparaginyl bonds.  Can also cleave aspartyl bonds slowly, especially under acidic conditions.  Required for normal lysosomal protein degradation in renal proximal tubules.  Required for normal degradation of internalized EGFR.  Plays a role in the regulation of cell proliferation via its role in EGFR degradation.  May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system (By similarity).
What are the official names of this protein?
Legumain, Asparaginyl endopeptidase, Protease, cysteine 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RSMB_ECOSM
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRVNRTHHSRDRWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEFA1_PAEAU
Sequence: VNQSETPVKHIGKVF
What are the official names of this protein?
Fibrinolytic enzyme FA-I, Fibrinolytic enzyme FA-1.
Protein: RSGA_DICNV
Sequence: MSKLSHQQQRRIHNHRQNKLAAGDRADAALVVAHLGYQLIVDDHGEILAADWRQKLGAIAVNDRVLITRDQPQHAIVEGIYPREKTLYKQHAGKLKPVASNIDQLLITFAPVPDWQNALLDRFLVAAHQAHIEPAFFCNKSDLFDAQTFAAAENRLAIYHQLGYRVFYGSIYQKTGLEELTHWLSGRQTVICGQSGVGKSSFIHYLMPDIDVWTQAVSAARGFGQHTTRNARRYPLDAHTAIIDTPGVRGFSLTHLQHSEVVSGFPEIHQYTHECRFNDCSHQHEPDCGVQRALERGDISLERFNSMMQICAEREV
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2V1_GEOSE
Sequence: MNKQASGKDTGNRGAVTGGKQMDGFADMLTNLLSKVGISNHEVFTSEKPHLPGYFRATKKWDFLVVKTNDRGEKYLLAAVELKSHVGPSFGNNLNNRVEESLGSATDIWIAFREKAFKNSRAPWLGYLMLLEDCPQSTKPVKVDEPHFEVFPEFKNASYAKRYELFCRKIVLERKYTSSCLLMSDKQGGLQGIYKEPANDLKIYPFLYSLLTHVATEAALISSS
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme BstVI, R.BstVI, Endonuclease BstVI, Type-2 restriction enzyme BstVI.
What is the protein family that this protein belongs to?
Belongs to the XhoI type II restriction endonuclease family.
Protein: ARAG_BURP1
Sequence: MAAALRFDNIGKVFPGVRALDGISFDVQAGQVHGLMGENGAGKSTLLKILGGEYQPDSGSVLVDGRAMRFPSAAASIAAGVAVIHQELQYVPDLTVAENLLLGRLPSALGWVRKRDAQRFVRERLAAMGVDLDAQAKLRRLSIAQRQMVEICKALLRNARVIALDEPTSSLSHRETEVLFKLVDDLRRDGRALIYISHRMDEIYRLCDACTIFRDGRQVASHASLANVPRETLVRQMVGREISDIYHYAPRALGDVRLSARALEGDALRAGASFDVRAGEIVGFFGLVGAGRSELMRVIYGAQRRTGGALTLDGEPLDIRSTRDAIRRGIVLCPEDRKEEGIVAHASVAENINISCRRHGLRAGLFLDRKREAETADRFIKLLKIKTPNRRQKIRFLSGGNQQKAILARWLAEPDLKVVILDEPTRGIDVGAKHEIYGVIYELAKRGCAIVMVSSELPEVLGVSDRIVVMREGRIAGELARGEANEEAVLNLALPQGATAHAA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NQOR_PARPJ
Sequence: MAKVLVLYYSMYGHIETMADAVAEGARSVPGTEVTIKRVAETIPADQAAAHGVKLDQKAPVATPDELANYDAIIFGTPTRFGNMAGQMRTFLDQTGGLWMKGALVGKIGSVFASTGTQHGGQETTITSFHSTLLHQGMVIVGVPYSCAGLVNMTEITGGTPYGATTLAGADGSRQPSQNELDIARFQGKHVASLALKIAG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: ACTC_RAT
Sequence: MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, alpha cardiac muscle 1, Alpha-cardiac actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RECO_LARHH
Sequence: MSQPGKVKGQQAFVLHAQPYKETSLLVEMFTREHGRVGLVARGARRPRAGIRALLLPFSPLEVGWFGKSDIRTLSDIDWQGGLPQLAGTPLVTGFYVNELIMKLVARDDPHEGLFDDYRTLIAHLARGSVAIAPVLRRFELQLLAATGYAPTLDRDLAGEPVRADAVYGFVPGEGARPGAERGCEVSGQTLLALDHGALDQASAAVLREARFLNRALLTHALAGTELASRALLNEVAALSDN
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PQQC_PSEMY
Sequence: MSQAAMTPAEFEQALRAKGALYHIHHPFHRAMYEGRATREQIQGWVANRFYYQVNIPLKDAAILANCPDRETRREWIQRILDHDGAPGEEGGIEAWLRLAESVGLDREQVLSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPTIHQSRLDAWPQHYPWIDAAGYDYFRNRLSQARRDVEHGLRITLEHYRTRDAQEHMLNILQFKLDVLWSMLDAMSMAYELERPPYHTVTAERVWHKGIDL
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: RPOB_RHIEC
Sequence: MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVEEPKGGRPDEGLQAVFKSVFPITDFSGASMLEFVSYEFEPPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQSVYMGDMPLMTNNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVYARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYKRDGEGWRIPFKPETLKGAKAITEMVDADTGEVVVEAGKKLTPRLLRQLSDKGLKALKAGDDDLYGNYLAEDIVNYSTGEIYLEAGDEIDEKTLAVILANGFDEIPVLGIDHINVGAYIRNTLSADKNENRQDALFDIYRVMRPGEPPTMESAEAMFNSLFFDAERYDLSAVGRVKMNMRLDLSVEDTVRTLRKDDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRRIVDGKVTNDVLYLSAMEEAKYYVAQANAELNADGSFVDEFVVCRHAGEVMLAPRDSMNLMDVSPKQVVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVARDSGAAIGARRGGVVDQVDATRIVIRATEDLEAGKSGVDIYRLQKFQRSNQNTCVNQRPLVTVGDVVNRGDILADGPSTDLGDLALGRNALVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTYGTIVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQAILDRNVYGRLIDMLRGQVSIAGPKGFKKGTELSNAVVSEYPRSQWWMFAVEDEKVQSELEALRGQYDESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHVDVVLNPLGVPSRMNVGQILETHLGWACAGMGRQIGELIEAYKANGNIEPLRKTIGDVVGAGPKAEQVHEFDDESVLRLADQWKRGVSIATPVFDGANEGDVNDMLRLAGLKDTGQSTLYDGRTGEQFDRQVTVGYIYMLKLNHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVELENTKLDEAQATQLPDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CDS1_MOUSE
Sequence: MLELRHRGGCPGPGGAGAPPPREGEAAGGDHETESTSDKETDIDDRYGDLDARGDSDVPEVPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMIWFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVIFGFIAAYVLSKYQYFVCPVEYRSDVNSFVTECEPSELFQLQNYSLPPFLQAVLSRETVSLYPFQIHSIALSTFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRGPNPSKVLQQLLVLQPEQQLNIYRTLKIHLTEKGILQPTLKV
What is the function of this protein?
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (By similarity).  Exhibits almost no acyl chain preference for PA, showing no discrimination for the sn-1/sn-2 acyl chain composition of PAs (By similarity).  Plays an important role in regulating the growth of lipid droplets which are storage organelles at the center of lipid and energy homeostasis (PubMed:26946540).  Positively regulates the differentiation and development of adipocytes (PubMed:26946540).
What are the official names of this protein?
Phosphatidate cytidylyltransferase 1, CDP-DAG synthase 1, CDP-DG synthase 1, CDP-diacylglycerol synthase 1, CDS 1, CDP-diglyceride pyrophosphorylase 1, CDP-diglyceride synthase 1, CTP:phosphatidate cytidylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MED16_XENLA
Sequence: MDVAYICEWDRRPRTSHCPSIPLVCAWSCRNLIAFTTDQRNEEEKDITNLIHILDTEHPWDVYSINSGHQEVITCLEWDQSGSRLLSADADGRIKCWGMTDHLANSWQNLVGSEVDGDPIVALSWLHNGVKLALHVEKSGVSSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPNGQVLTATESLCRLRCRVALADIAFTGGGNIVVATCDGSSTSPVQFYKVCVSVVSEKCKIDTEILPSLFMRCTTDPARKDKFPAVTHLKFLARDMSEQVLLCASNQCSSIAECWSLRKEGLPLNNIFQQLSPAVSDKQPMILKWRILSATNELERVSAVALPKLPISLTNTDIKVASETKFYPGLGLALAFHDGNVQIVHRLSLQPMAVLYGSSLRPSEEPSLKRQRSPTPCIHFKALQMSWTSLALVGLDTQGKLSILRVSPSMGHSLDMSTSLRHLLFLLEYCMVTGYDWWDILLHVQPGMVHNLVEKLNEEYTRQNAALQQVLSTRILAMKASLCKLSQTTVTRVCDYHAKLFLISISCTLKSLLRPHVLNTPDKSPGDRLTEICNKFTDTDIDKVMINLKTEEFVLDMPTLQSLQQLIQWLGDFVLYLLVSLPNQGSSVRPGHSFLRDGASLGTLREMMVMIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTRLWLCCPPHNQRLIT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_YERPY
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWSGMAKQFEPHHVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLRVVGQLKSRLGANPVPLQLAIGAEEKFTGIIDLVKMKAINWNEADQGVTFEYEEIPADMAELAAEWHQNLVESAAEASDELMDKYLGGEELTEEEIKKALRQRVLKSEIILVTCGSAFKNKGVQAMLDAVIEYLPAPTDVESINGILDDGKDTPAVRHSDDKEPFSALAFKIATDPFVGNLTFFRVYSGIVNSGDTVLNSVKSQRERLGRIVQMHANKREEIKEVHAGDIAAAIGLKDVTTGDTLCDPNNPIILERMEFPEPVISVAVEPKTKADQEKMGMALGRLAKEDPSFRVWTDEESGQTIIAGMGELHLDILVDRMRREFNVEANVGKPQVAYRETIRETVKDVEGKHAKQSGGRGQYGHVVIDMSPLPPGGVGYEFVNEIVGGSIPKEFIPAVDKGIQEQLKSGPLAGYPVVDVKVRLHYGSYHDVDSSELAFKLAGSIAFKEGFKRAKPVLLEPIMKVEVETPEDYMGDVMGDLNRRRGIIEGMEDTATGKTVRVKVPLSEMFGYATDLRSQTQGRASYSMEFLEYAEAPSNVAKAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y027_CAUVC
Sequence: MMLQIPEVLTKAQVAECRAILDAGPWVDGNVTSGFQAAMAKNNEQLPQDSAEARHVGAIIVQALEANPLFVSAALPRTILSPMFNRYGEGMGFRDHVDNAIRRDPVTGQRLRTDLSCTLFLAEPEDYDGGELVVNDLYGDHVVKLAAGDAILYPSTSLHHVTTVTRGRRTASFFWIQSLIRDDARRSLLLDMDVAIQQLSRKVERDDEAILSLTGVYHNLLRQWAEV
What are the official names of this protein?
PKHD-type hydroxylase CC_0027.
Protein: GATB_CHLTA
Sequence: MGIAHTEWESVIGLEVHVELNTESKLFSPARNHFGDEPNTNISPVCTGMPGSLPVLNKDAVRKAVLFGCAVEGDVALFSRFDRKSYFYPDSPRNFQITQYEHPIVRGGCIRAVVEGEEKTFELAQTHLEDDAGMLKHFGDFAGVDYNRAGVPLIEIVSKPCMFSAEDAVAYANALVSILGYIGISDCNMEEGSIRFDVNISVRPRGSRELRNKVEIKNMNSFTFMAQALEAEKRRQIEEYLSYPNEDPKKVVPAATYRWDPEKKKTVLMRLKERAEDYMYFVEPDLPVLQITETYIDEVRQTLPELPHSKYMRYITDFDIAEDLAMILVSDRHTAHFFETATMSCKNYRALSNWITVEFAGRCKARGKTLPFTGILPEWVAQLVNFIDRGVITGKIAKEIADRMVSSFGESPEDILRRHPSLLPMTDDHALRAIVKEVVAQNTASVADYKNGKAKALGFLVGQIMKRTEGKAPPKRVNELLLAAMRDM
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RPOA_NITOC
Sequence: MQVSNFLKPRIVDVQRINDYATKVTLEPLERGFGHTLGNALRRILLSSMPGCAIIEAQIDGVLHEYTTKEGVQEDMTEILLNLKGVAVKLHGRDEVTLNLSSKGPVTVTAGDIQLEHDVEVINPEHVIAHLTKSGELNLTMKVVRGRGYQSASMRIPKEEDERSIGHLILDASFSPIRRVTYEVDSARVEQRTDLDKLIIEIETNGTIAPDEAVRKAATILQDQLTAFVELEGKIETAKEKKAAEIDPVLLQPIDDLELTVRSANCLKAENIYYIGDLIQKTEVELLKTPNLGKKSLTEIKDVLTLRGLSLGMRLENWPPAGLREEETKVTA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SSMM1_HUMAN
Sequence: MGDLFSLFWEVDPPPIPVNCAIPNQDYECWKDDSCGTIGSFLLWYFVIVFVLMFFSRASVWMSEDKKDEGSGTSTSVRKASKETSCKRQSKDSAWDPSQTMKKPKQNQLTPVTNSEVALVNAYPEQRRARRQSQFNEVNQNQHDSDTTEYGSEESNSEASSWKESESEHHPSPDSIKRRKMAQRQRNLGSYQMSERHCLHCKALRTNEWLAHHSRQKPSVTPPMKRDSQEESSISDINKKFSKF
What are the official names of this protein?
Serine-rich single-pass membrane protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RBSR_ECOL6
Sequence: MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDNSLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA
What is the function of this protein?
Transcriptional repressor for the ribose rbsDACBK operon.  RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site.  The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon (By similarity).
What are the official names of this protein?
Ribose operon repressor.
Protein: CYAA_PASMU
Sequence: MNYDLFSAQKKVEYLDKLRIERALSGSSGEFQHVFQLLTLLLHINHPNLPGYVADAPVGIADFVISPYQKQYLLTTVPSLEANQSLLPSFSYRSTNAILGVYVMGSIASISQTPKSDLDTWVCHRDDLSTKEKEALQRKTHLLKNWAKQFNIEINFYLMDQKRFRCFRYAEPLTAENCGSAQYMLLLDEFYRSAIRLAGKPLLWLHLLIEQEENYESEVERLVRTQQICLDDWVDFGGLGQLSANEYFGASLWQLYKGIDAPYKSVIKILLLETYSSEYPNTYLIARQFKEELLTGKLNPSHHFDPYLAMLQRATRYLTKHNELKRLGFVRRSVYLKATEGMCWQDPNATNNWRLQHLQKLIQEWDWSDALIEELNQRANWKIKQVKKAHNSLIKFLMLSYRNLVAFARKHKVNSSIMPQDISVLTRKLYTAFEELPGKITLLNPQISLNLSEKNLLFFEVKGSKTFKDGWYVVNQTPSVAGFVQKRYTEYSESLNKLVAWAYFNRILTANTDLHIISPNVSLTTLRHFVTDLRLSFPVTVSSVTNEDLTHACEIRSLIVAVNLTVDPTKKITQVKSRIQASDLFSFGPKEESLVGSIDITYRNLWNEIRTLHFEGPNAILLALKVLSNKIHRGAPSPKLIQVFSYSHRYRRTLSNIVTALINRCISIQIGDALPPQNNLLRVAGKNWQFFFEERGISLQEIHSNEELEATGFDTALQTEVEEKESALPDTSRTYPPEIDHFASEGFLQFFFEDNSDGSFNVYILDEANRIEIYRNCDGQKEKKILEINHIYQSSGLDENNNPYKIVQRDFNYPQFYQLLLQENGVKIVPFHSRLAMS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.