PharMolix/UniProtQA huggingface dataset:
Protein: RS18_SHEWM
Sequence: MARYFRRRKFCRFTAEGVTEIDYKDIVTLKNYITESGKIVPSRITGTNAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AAEX_CITK8
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FXJ1B_DANRE
Sequence: MPVLMSPEIANKFKEKWLMLHPEDQDNVSGSVHFDDSLTSLHWLQNFSILSANPERTPSSGCHPQHLFYYKNQLGGTDSPSSPPAGDTAATGMPQTPGNPTTSCSSLANPYALQQAGHYITGQTNPAEEIDYKTNRHVKPPYSYATLICMAMQASNKTKITLSAIYSWITENFCYYRYAEPSWQNSIRHNLSLNKCFMKVPRQKDEPGKGGFWQIDPQYADMFVNGVFKRRRMPATNFNTQRQSKMLSSPSSSYTSQCNQQMGMGHFQGNKRKQVFPKRGNKLARISKSPLLTSDIKTSDVLRGDFDLASVFDDVLSGNDSTFEDLDINTALSSLGCEMEPSSQIHNQSGYSNEDEQACAYLEANGIIGCNMEDFHHQQHHQQAQVHPQYYEGMFSDQQNQQHPWEIKEEAQPVPLSLDHGYAFCEGFFSEMQLWERGESYM
What is the function of this protein?
Key transcription factor required for motile ciliogenesis.  Activates genes essential for motile cilia formation and function.
What are the official names of this protein?
Forkhead box protein J1-B.
What is the protein family that this protein belongs to?
Belongs to the FOXJ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_ANADF
Sequence: MERGNRKSRIGVVVSNKMAKTVVVKVERRVADPKYGKIVKRAEKYKAHDENNACQIGDKVRIVETRPMSKDKRWRIAETLEKAEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CRCB_THEKO
Sequence: MNLRIAMAIALGGAFGAVARFYISGLLPVYRDFPVGTLMVNSIASLILGYLYGLLFWGFDVPPDWRAFFGTGFCGALSTFSTFSYETFSLLREREYLIATLNILANVIITIALVFAGFMLARR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_ALKMQ
Sequence: MATGNVGKLVQIIGAVVDIRFSSEEIPALLSAITIQGPDGLVTVEVAQHIGDDTARCVAMRSTDGLVRGMEAIDTGAPITVPVGRETLGRIFNVLGEVVDEGKPVEAKMHLPIHREAPSFEEQEAATEIFETGIKVVDLIAPYARGGKVGLFGGAGVGKTVLIMELINNIAKEHGGLSVFAGVGERTREGNDLYHEMIESGVIDKTSLVYGQMNEPPGARMRVGLTGLTMAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRQISELGIYPAVDPLDSNSRILDPATVGQEHYEVARGVQEVLQRYKELQDIIAILGMDELSDEDKLTVARARRVQRFLSQPFFVAEQFTGMAGKYVPLKETIRGFKEILDGKHDDLPESAFLFVGSIDEAVEKANKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SURE_METTP
Sequence: MRRILVTNDDGIYAPGLRAAVRSVEDLGEVIAVAPSGQRSGVGRSVSVFEPLRMAEVNLDGKKAYAVSGTPTDSVILGIFVVMNGELPDLAVSGINVGENISTDTVTTSGTIGAAIEAASYGVPAIAASIQVADQGDKFDNNHSVEYKFDTAMNLLRRVASRVLERGMPVGVDILNINLPLNATEDTEIVVTRLARKIFKTAVEERRDPRGRPYYWIGGDLICSEREGTDVRAVYQEGKISVTPLTIDSTAKVDFGEIMDLLEVI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_KLEP3
Sequence: MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFRTQMPAALAYPLQGKRYNWAYETEPEPYMNHRRMECGRGKGLGGSSLINGMCYIRGNAMDLDNWAKEPGLEHWSYLDCLPYYRKAETRDIGPNDYHGGDGPVSVTTPKPGNNPLFEAMVTAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQARGRPNLTIRTHALTDHIIFAGKRAVGVEWLEGESTIPSKATANKEVLLCAGAIASPQILQRSGVGNPELLRQFDIPVVHDLPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGIGASNQFEAGGFIRSRAEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRLKSRDPHAHPAILFNYMSHEQDWQEFRDAIRITREIMNQPALDKYRGREISPGTECQSDAELDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGVRVVDASIMPQIITGNLNATTIMIGEKMADAIRGRQPLPRSTAAYYVAGGAPVRR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: MURC_VIBVU
Sequence: MTIQHKQDLAQIRAMVPEMRRVKSIHFIGIGGAGMSGIAEVLLNEGYQITGSDIAENAVTERLAQKGAKVYIGHQATNVAEASVVVVSTAINEANPEVKAAREARIPVVRRAEMLAELMRFRHGIAVAGTHGKTTTTALVTQIYSEAGLDPTFVNGGLVKSAGTNARLGSSRILIAEADESDASFLHLQPMVCIVTNIEADHMDTYGGDFETLKQTFIDFLHNLPFYGQAIVCIDDPVIRELIPRISRQVITYGFSEDADVRIENYRQEGQQGKFTVVRKDCEALDITLNIPGRHNALNAAAAIAVATEDEIGDDAILAAMVGTQGTGRRFEHLGEFETGNGNVMLVDDYGHHPTEVDVTIQAARNGWQEKRLVMIFQPHRYSRTRDLYDDFANVLEQVDVLVMLDVYAAGEKAIAGADSRSLCRTIRSRGKIDPIFVADTQQLPEVLANILQEGDLLLAQGAGDIGKVARQLAALELNISNMKAK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_NICTO
Sequence: MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDITVKARRVGGSTHQVPIEIGSTQGKALAIRWLLAASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IORF_CVHN5
Sequence: MLEVEAPLEIVQESSRKLLGLTNLSEAIKPIIEAENPNQNSLCLLNHKETLSHIIPGSLGLPNFKKVETLNFQMVKEYPLLTGYPLLKQKDIGINTTGVLLKQLMVNKSSCYQDGISTISVPVHMPVHPMVMPTKVSSGSLVTKLILLFPPMFRQGILLFKKLSLLGFRLVRFCLKAIMLKAQEGLLLIAGQVHVLNHVDPIIVH
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Orf8 protein, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ZN654_HUMAN
Sequence: MAEEESDQEAERLGEELVAIVESPLGPVGLRAAGDGRGGAGSGNCGGGVGISSRDYCRRFCQVVEDYAGRWQVPLPQLQVLQTALCCFTTASASFPDECEHVQYVLSSLAVSFFELLLFFGRDEFYEEPLKDILGSFQECQNHLRRYGNVNLELVTRIIRDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIKSCINHPEISKDLYFHQALFTCLFMSPVEDQLFREHLLKTDCKSGIDIICNAEKEGKTMLALQLCESFLIPQLQNGDMYCIWELIFIWSKLQLKSNPSKQVFVDQCYQLLRTATNVRVIFPFMKIIKDEVEEEGLQICVEICGCALQLDLHDDPKTKCLIYKTIAHFLPNDLEILRICALSIFFLERSLEAYRTVEELYKRPDEEYNEGTSSVQNRVRFELLPILKKGLFFDPEFWNFVMIKKNCVALLSDKSAVRFLNESTLENNAGNLKRTEEQQGLDEGFDSLTDQSTGETDPDDVSGVQPKGHINTKKNLTALSTSKVDHNVPRHRCMLCNKEFLGGHIVRHAQAHQKKGSFACVICGRKFRNRGLMQKHLKNHVKKIQRQQIAAAQQDDQEVTALEEINCSSSSISFENGNSDSKDLEVETLTASSEGNKEVIPEHVAEFIEIPISVPEDVIENVIENGSPNNSLNNVFKPLTECGDDYEEEEDEEGDYEEDDYDLNQETSVIHKINGTVCHPKDIYATDQEGNFKCPALGCVRIFKRIGFLNKHAMTVHPTDLNVRQTVMKWSKGKCKFCQRQFEDSQHFIDHLNRHSYPNVYFCLHFNCNESFKLPFQLAQHTKSHRIFQAQCSFPECHELFEDLPLLYEHEAQHYLSKTPESSAQPSETILWDVQTDSNPNQEKDSSSNEKQTISLPVSTSKSRKESTEPKTCIESMEKKTDSLVQNGNERSDDTVSNISLIDQKMPDIEPNSENNCSSSDIVNGHSEIEQTPLVSSDPALKIDTNRIRTENGSILPSVVPQEHNTLPVSQAPSKPNLTSEHTSYGLILTKPYVRPLPPSYLDERYLSMPKRRKFLTDRVDACSDQDNVYKKSVKRLRCGKCLTTYCNAEALEAHLAQKKCQTLFGFDSDDESA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 654, Melanoma-associated antigen.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_STAEQ
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGIGASVVFEVDEGLRTLLDFRYQRHFKAKKGENGQSSNMHGRNAEDLVLKVPPGTIIKSVESEEVLADLVEDGQRAIVARGGRGGRGNSRFATPRNPAPDFSENGEPGEELEVTLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDHRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGRNPLDDYKIINQELINYKQRLEDRPQIIVANKMDLPDSQGNLSHFKEQLDNDVTVVPVSTITRDNIDQLLYQIADKLEEVKDVDFSVEEDENLGVNRVLYKHTPSADKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCSNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_RICCN
Sequence: MSNSNIHTTAVIAEGAKLGKNVKIGPYCIIGPEVVLHDNVELKSHVVIEGITEIGENTVIYPFASIGQPPQILKYANERSSTIIGSNNTIREYVTVQAGSQRGGMMTRVGNNNLFMVGVHIGHDCKIGNNVVFANYVSLAGHIGVGDYTIIGGLSAVHQYARIGEYSMIGGLSPVGADVIPFGLVSSKRAVLEGLNLIGMNRKGFDKVKSLSALKAIEEIFSGEGNFAERIKQVAEKYNNNSIVIQIIDFLNQDSNRAFCRFEK
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNAA_BOVIN
Sequence: MAPAWSFLLSLLLLSCNAICSLGCHLPHTHSLANRRVLMLLQQLRRVSPSSCLQDRNDFEFLQEALGGSQLQKAQAISVLHEVTQHTFQLFSTEGSPATWDKSLLDKLRAALDQQLTDLQACLTQEEGLRGAPLLKEDSSLAVRKYFHRLTLYLQEKRHSPCAWEVVRAEVMRAFSSSTNLQESFRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-A.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3720_BACCZ
Sequence: MTLQTFKSTDFEVFTVDGLEERMSAIKTNIHPKLEALGEQFAAYLSKQTDENFFYHVAKHARRKVNPPNDTWVAFSTNKRGYKMLPHFQIGLWGTHAFIYFGLIYECPQKVETAHAFLEHLNDLKTNIPNDFVWSIDHTKPSVKLHKTLETEDLQKMIERLATVKKAELLVGIHISPEEFSAMTNEQFLAKIESTMQSLLPLYALCNR
What are the official names of this protein?
UPF0637 protein BCE33L3720.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: RHNO1_HUMAN
Sequence: MPPRKKRRQPSQKAPLLFHQQPLEGPKHSCASTQLPITHTRQVPSKPIDHSTITSWVSPDFDTAAGSLFPAYQKHQNRARHSSRKPTTSKFPHLTFESPQSSSSETLGIPLIRECPSESEKDVSRRPLVPVLSPQSCGNMSVQALQSLPYVFIPPDIQTPESSSVKEELIPQDQKENSLLSCTLHTGTPNSPEPGPVLVKDTPEDKYGIKVTWRRRQHLLAYLRERGKLSRSQFLVKS
What is the function of this protein?
Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase.  Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner.  Required for the progression of the G1 to S phase transition.  Plays a role in the stimulation of CHEK1 phosphorylation.
What are the official names of this protein?
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1, RAD9, RAD1, HUS1-interacting nuclear orphan protein.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA damage in a H2AX-independent manner.
Protein: GPD1_SACUV
Sequence: MSAAADRLNLTSGHLNAGRKRSSSSVSLKAAEKPFKVTVIGSGNWGTTIAKVVAENCKGYPEVFAPIVQMWVFEEEINGEKLTEIINTRHQNVKYLPGITLPDNLVANPDLIDSVKDVDIIVFNIPHQFLPRICSQLKGHVDSHVRAISCLKGFEVGAKGVQLLSSYITEELGIQCGALSGANIATEVAQEHWSETTVAYHIPKDFRGEGKDVDHKVLKALFHRPYFHVSVIEDVAGISICGALKNVVALGCGFVEGLGWGNNASAAIQRVGLGEIIRFGQMFFPESREETYYQESAGVADLITTCAGGRNVKVARLMATSGKDAWECEKELLNGQSAQGLITCKEVHEWLETCGSVEDFPLFEAVYQIVYNNYPMKNLPDMIEELDLHED
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_STRCO
Sequence: MTAAVPAGATGRAKKVVVFDYGFGNVRSAERALARAGADVEITRDYDKAMNADGLLVPGVGAFAACMEGLKAARGDWIVDRRLSGGRPVMGICVGMQILFSRGIEHDVEAEGLDEWPGTVGPLEADVVPHMGWNTVEAPADSQLFAGLDADARFYFVHSYAVHEWTQESHNPLIAEPRVTWSTHGKPFVAAVENGALWATQFHPEKSGDAGAQLLTNWIETL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_SULIN
Sequence: MSIDQRLQLITRNAAEIITIDELRKKIESEEKLKGYIGFEPSGLFHIGWLIWTQKVKDLVEAGVNMTLLRATWHAWINDKLGGDLSLIKMAADYTVEVIKNYGVDTTKLNIVDADDMVKEKDYWALVIKVAKNASLARIKRALTIMGRRAEEAEIDASKLIYPAMQVSDIFYLDLDIALGGTDQRKAHMLARDVAEKMGKKKIVSIHTPLLVGLQGGQRMSITEGMEEDDIQAEIKMSKSKPESAIFVSDSREDVERKIMGAYCPKGVAENNPILQILKYIIFPRYNFVKIERDIRYGGDVEFKDYEELERAYIEGKIHPMDLKKATARRLNEILEPIRKSLERKPEFEEMIQKISKSVTR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_MICLC
Sequence: MAGLQGWQLVIIILLAILLFAAPKLPAMARNLGQSMRIFSSEVKQMRTEGKDAKDERSGTGSTAADEPVEGRVVDRDETDPRDQR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SUCB_TRIVA
Sequence: MLSSSFARNFNILEWQSKEICAKYNVAAGINLVARSPEEAAEAFRKMNLPAAVIKAQVYCGGRGKGHWLETGFKSGVHFVKSADEAAKIAKEMLGHHLVTKQTGKDGLLCQAVMLSDPVEVKRELYFAILLDRQTQSPVVIASTEGGVEIEEVAAHHPEKIHKFVLDGVEGITEEVAKNISTKLGLTGKAYDNGVVEMQKLWKLFVGSDATQVEVNPLAETTDGRIITVDSKFNFDDSAHYRQKQIFGYRDLKQVNPFEIRAEKYGLNYVPLDGNVACLVNGAGLAMATMDVIKLAGGDPANFLDLGGAASEAAVTEGFTIISQQSHVKAILVNIFGGIVRCDMVAAGVIAAFKKVGLKVPLVVRLEGTNVEAGKKLIRESGLPIISADNLTDAGEKAVKAAKGEKF
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, hydrogenosomal, Succinyl-CoA synthetase beta chain, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Hydrogenosome.
Protein: NEUA_MOUSE
Sequence: MDALEKGAVTSGPAPRGRPSRGRPPKLQRSRGAGRGLEKPPHLAALVLARGGSKGIPLKNIKRLAGVPLIGWVLRAALDAGVFQSVWVSTDHDEIENVAKQFGAQVHRRSSETSKDSSTSLDAIVEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRFGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSALKLDCKTEVSVSDKLATVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSAVPADACSGAQKAVGYICKCSGGRGAIREFAEHIFLLIEKVNNSCQK
What is the function of this protein?
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid.  Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
What are the official names of this protein?
N-acylneuraminate cytidylyltransferase, CMP-N-acetylneuraminic acid synthase, CMP-NeuNAc synthase.
What is the protein family that this protein belongs to?
Belongs to the CMP-NeuNAc synthase family.
Protein: VA5_POLFU
Sequence: VDYCKIKCSSGIHTVCQYGESTKPSKNCADKVIKSVGPTEEEKKLIVNEHNRFRQKVAQGLETRGNPGPQPAASDMNNLVWNDELAHIAQVWASQCQILVHDKCRNTAKYQVGQNIAYAGGSKLPDVVSLIKLWENEVKDFNYNKGITKQNFGKVGHYTQMIWAKTKEIGCGSLKYMKNNMQHHYLICNYGPAGNYLGQLPYTKK
What are the official names of this protein?
Venom allergen 5, Allergen Pol f V, Antigen 5, Ag5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PPR29_HUMAN
Sequence: MLRLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITVLQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDASAGPAIKLHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTLDKLRAHTEYTFCVTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGMVIVLGAVYYCLRKRRMQEEKQKSVNVKKTILEMRYGADVDAGSIVHAAQKLGEPPVLPVSRMASIPSMIGEKLPTAKGLEAGLDTPKVATKGNYIEVRTGAGGDGLARPEDDLPDLENGQGSAAEISTIAKEVDKVNQIINNCIDALKLDSASFLGGGSSSGDPELAFECQSLPAAAAASSATGPGALERPSFLSPPYKESSHHPLQRQLSADAAVTRKTCSVSSSGSIKSAKVFSLDVPDHPAATGLAKGDSKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGGGIHHLEVKPAYHCSEHRHSFPALYYEEGADSLSQRVSFLKPLTRSKRDSTYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHHREEVYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKL
What is the function of this protein?
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 29, Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2, Leucine-rich repeat and fibronectin type-III domain-containing protein 6, Leucine-rich repeat-containing protein 62.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS4_BURA4
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGENLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKSITVNGVVANVPSQQVKAGDVVAIREKAKKQARIVEALSLAEQGGMPSWVAVDAKKFEGTFKQMPERADIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MOC2A_PYRTR
Sequence: MAPGKAPAGHFSILYFAAASTFTGKTSEHLPAPVRARHVFTMLEERYPGIGDKVLSSCAVTVNLEYVDIGEEDAEQQIEEGDEVAIIPPVSSG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by uba4.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Common component for nitrate reductase and xanthine dehydrogenase protein G, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA21_ACASE
Sequence: NLLQIGIMKRCANKRRRPVFHYRDYGCYC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that has myotoxic activity but no significant neurotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 acanmyotoxin-1, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BST17_CAEEL
Sequence: MTVSYQLDVSSGNPLLFLRLLGRWRGSIWKSVVGDLFVWLLFYYAIYFAYRYAFSKQLQTVFEEISIHTDDRMKYLPLTFMLGFFVTTVFERWRSALNVMPFIESVALSVAVLLPGKGREDRLTRRAIIRYVVLHQILVFRDISMRVRRRFPTLKYVVDAGFMRQEELDVLESVNQESSQTYWVPINWANSLALVAHQQKLIDQPTAFNNVIFAIKEFRVAMETLIKFDAIPIPIAYPQVVFLAVRVYFAICLVSRQFLISDMKSKTQMDWPVPIMTVLEFIFVIGWMKVAEVLLNPLGEDDDDFEVNSIIDNNISRGMAIVDTTHGYHPDLVDDVFSDPNYLPAYSENSQIPRNLTGSAAKVELAAPTDEVKIVRVNPEDAPPTSERGSMFTRRNAYSLRNRKISIASNNLESPSQERKFNLSMPAGMLNKSTQPDRPTMETVSEEHEPSHFYRGDRVHSSDSGLSKTQQSSEESVDKKG
What is the function of this protein?
Forms chloride channels.
What are the official names of this protein?
Bestrophin homolog 17.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRH_METPP
Sequence: MPAFKRILLKLSGEALMGDDAYGINRATIVRMVQEVREITEMGCEVAVVIGGGNLFRGVAGGAVGMDRATADYMGMLATVMNALALADTMRQEGMTARVMSAIGIEQVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAQIVLKATKVDGVYSADPKKDPGATRYAKISFDEAISKNLQVMDATAFALCRDQKLPIKVFSIFKPGALRRVVTGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.