Protein: MED12_CAEEL
Sequence: MLRKTNLRMGTADVYKQNKNQEEDMLTTERLKKGYQMPLTQYELQSLVFNASENKLIRLEKAQKRSQSMIASVIHKKGEFHMNYDRERKIPKEQLPCFAPHNWKRILSDRVKFFSALARGTPLQQLSQRIPGFRRKELLFLEFSDYNISYDRAIWCVKLLCILGFNSSSKTQKKTLLDVATLELSQACNKTTIWLVTQLYKSFRNPIKRREATKTWNYLTGFMKYMFDDGVLDKQEFLNDLTEVFNQLFLQKNFKNPSVLSTFMKYYVYFVEDLSSSLVLARRSSTLLCQALGFLFEMAQDKRKIDAYYDSANKTFIKKEFENEDGEIYEFEDYDDFIDMLDEIPDVPYFDETDKTPEAQAEELIKQHEKRKAGSLKKSERRRRRGLSKNRPKKMPQNPSNEASLDHDKVQIKQEPMDYDEYGGQQSDNSMDYDSFSHQYDPSYEPLPFKPLHTDIPKKLTDDEEFKYMKIGKRSVTPERISGRYGSMTYPFWIQQGGVGIDPPKDEVLDFSNPTPTETVNTQPQIDFESSPSASPALSVDKENECEKKEDESKTKEKNKDKEKDKEKEKSVDEHTNDLDVPINPDDAEMADANDKTDASEKQKLVEEEPTGKENEDDTSSKTAKTSTSAEKSEAPSIVDSNDKIDKEPNASSTSNDETSKDDTVPMESDPPAATEKPKESTEITTEEPLEVDKAPEVDKSEKEHEDDIMIIESNKKADEDDCVVIAVVDPDQEQTPESEKKKDGEEERDKNKDTDVADNEPEKIYTDEELAEIKIRKEKEMKIATLASHIKEKMVSDKKWKEKTSHAGWRTLDQCSQFSEALHLLSSMVQYMACVTPESFVWNDLSVQQEERRHRILPQLCGSPLDYLPCELHKLPVMEGVEEVVDCLRLRHCEIVRRSQAAEDRWLPNAAFLQSFGRIIDTCVDVIGIMDNIDVEKPNAITNAGLRLFAFREKFEKQEALLKTMLMFKWCITEEREGSFRATYIAKLLRFGMDQNPENTIGGWQVMDLFFKFMSTEGPKHGSKMYQAHFDSTVAIMIEMMREKIFSITDILRELEKDSDLDYNAPLMERQRKQKIPKISKRHRKPETPDDTKLVHFTTEYTPKRLFMGKKMDLLERMIIILPQLDVDEDTDEYRLRRLLLFGLKPAANVYFRRARAIYKSITKEFTTRLYIEFDRSSKVTTAHKKINQNRLDDLLRQFRAQTYHDQHLILERIVYNFIDGIGGFLKKNCDDVPAPEVANIICEMYEFSMDITSIFDFFEMVNPYLKAVDDKIAHFRMDVLPDMYYTETAFIFVSFFMKHWQRFLLHPRACAIVNQCFVLIQDMIRADDHMITCWGRTVAIFVFHARKAIANAGLQNEEFLAEDSHFWRVFPNAQHVDLDVGYFNEDFAGVKLQLRGGTLRYDSYNDFKWLVSNMKPNLKKKPHLKRPNTRYSFVVRAFMEARQHGRNFDRINELANYCANITANDPPLSEYWIGAIKGLCFLSLDAPYPFKEMSQQIDISDCSTHYSLTTFITCLAGKSAFYIPRLLAELTKHVFPLMLRHDGRLTSQKTHDVKRKVASKTTESRTLSEAEPGVCLCLLIICGLCCVGDEPFGLSVHYRGIEKKKKRFNNTADERIMHLFHWFEMDHAMFRTLGHISQLLEALQSRCRDANLVLPKNFPIKNPPKHQQELHREKAPYRPQYLFNIAKTVQFVICEQDWVTLRMFRFFQTRKMEAFNQDKLKQNCLGQQILRMALRRRTERENVHKLFEAHKISKKATVDKVLSFMNLWNFRATLFDLMLMIKEISPDGNSRHAQQGAIAADALMSEIGKCCRDMFLSAYKTKIKMPIAKTLTDFRLSDINKFWLIAPLVRMCPKPINIPPQYANTTVGTVAAKFLREAALLMDTPPTTPKERLLQCSWAMSKVPFINMILTCLQCEKMQQSKDVFLQSLYTQLQRETLRDHHRRSNWTNRREHRDCTIFRITLIGYIYKEILKATHVETWGLLIFQLMFHGIINPVREKLIYETCFDMLHHMVLWTLVDGDSMNQHDRYGSIRVRWPQYAGLMKKIRKEMQERFTDQTRNSLHRFLPIGKMQMSTISYKKYQKRPKVNQKMSKKFLAGEGLKNGKYSFLPEEKAKTNAFEHTDHLGDLIVKGGWKFRMFQTTRLDKVAKNVQNVLRSNMHHTHVLEFNRPQLLMSDNMFDDIFLAPPDIEITKIIEQPVPVIDEEEAKKRAEEEKEAAEKKEESKNAEDEKNKNNAENKKDTKEGEKGKSKDKEKDGEKEKCKDASKKDDVTSEKNELEKRASDAAAATNAPETNKDMDTSTPKPAPVTRSPATRGRGGGRKRNSGARGGGPRAKRANSRADTAQAAAATTQWNAPIANTSNPAAGGNFHAAMRGNQPPMSNGSSDETKVHIRNLLNRKKEEKRNSLADASAAAAAANSNAMGNTSSMPPSGPPMPMGSSMQSAGATQQLQGMQKHQMGGSMSGMNQNMGGMNQSMSHQAPPPYSSTNEMNRPLMNQYGGPHFAAPNPGPLNRSSGPVSSETRQQIMEQQMREKLAAHHQLVEQQKQRDAREREAREREAREHQERMQREAYMKEQQLLERKRAIEENNRIMEEQQREREMEAARKEAARRAAEEAYAAEQQRLELLRRQEEERLRKEAEERMRIQRENEERVRQEQMRLEAEERERIRRAEEERIQKELEDKVRREKEEAARQEKERQEQEARMREAREAELSRQRMEQQRRSQQNPYMNQQGQYSQQPPPSYQQSSYPNNYQPGQQGNQPPNYQQPSHQSMQQGHQAGYQQTSNQMQMNMQQQQNRQQGGPQQSFSGPGGINQPSQPGYSGYNQQGGQGQQGQMQQQRNPFGNQQDMQQPGAAKLMHAKPNEAHAQQYQHTQNQLSLAQKEKEKQYFQAKNLQASQANAQQQQQRFGDVVAGNVAGYGRPYGQQQLGASDQMGTSQLPGASTSRMNQGSSNPQGGMQSYQQQQPVLGQPGPIQTGQSTQQQIPAQSQQQYNSGRPQMHTTPTKNDMSARAPSGAMGQIANRMGHGTNPQGYGSTGQNVPGGYQQGQQQSGQGSYPQAQQQQPNQYSGSNQQVGQQAQQQQQQPLNQNVSQSQSAAQFGRPSQDSAYQQSGYNQTGNQSYQRPDQQQQGAQQNQWSGSNQAQNQLRSQQQAQQPLQQPQQSQQFQQPAQQAKNPMAQSAQYGGFGGQQQGYDQQQQGQIAPQQAQNPQASQSYGQQQTQQNRYGMGSSGYTANSGGSSNILNQSMEESGLNQGFSGASSNASSQQGGSSQMQQSGYGMPGNQMQMQQNQKQQVQRGMPTGMGQTNMGQSGMGQSGMGQTGMSRSGLGGGIGQQGQQSQQPQQPQVSQQQNQRGMNPGAQLPPYSTGQQQHQPQQSQISQQQQQQDQYRRMQAAQMQQQPTAQGQQNRMGMPSQQQSGAAYSNQMQFQGVRQGQQGMGGMGGSGQQQPQTQPHGSNQYYQQQQDQRMQQQPQQPGQQQQHGYGMGQYPNQQPPNQY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Functions downstream of let-60 during vulval induction.  Required for asymmetric division of T-cells and for hypodermal development.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, CeTRAP230, Mediator complex subunit 12, Protein dumpy-22.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.