PharMolix/UniProtQA huggingface dataset:
Protein: CBPO_HUMAN
Sequence: MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSATMLLGLLVSCMSLL
What is the function of this protein?
Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins.  Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues.
What are the official names of this protein?
Carboxypeptidase O, CPO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor.
Protein: NFI_SULIM
Sequence: MVEKHLLEFLEKLQFLIAKNVKISHYGIENVKKICGVDIAYKGNLGFSVGVSMDINSGDYNYKSYVGEVNFPYIPGFLFMREAPLMIKAIEGLDCHLLLVDGHGIAHPRKSGIAAVIGVLLDFPTIGVAKSRLTGDLVNESEITYVYLNGEKVGVKFGRYFYSPGNKVDLQDCIELGKRGYPKVLKIADMLTKKIKKE
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_CHLAT
Sequence: MTQTGKSNIEAKAFARYITMSPYKVRRIVDQIRGRSYEEALMILQFMPYRACNPVLKVLYSAAANAKHNLGLNKSELSISEVKVDQGPVMKRFQPRAQGRGYPIRKPTCHISLTVKGLK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MATK_PLAAE
Sequence: MEEIQRDLQLERSRQQDFLYPLIFQEYIYAFAHDRSLSRSFLSENPDSENQVYENKSSLLIVKRLITRMHKQNHFLISTNDSKKNLFLGRNKDLDSLILLEGFAFIVEIPYSLRLISSLEGKRKKIEKSQTLRSIHSIFPFLEDNFSHLNFVLDILIPYPVHAEILVQTLRYWVKDAPSLHFLRXXLNDYWSLSTPKKAGLKRNQRFFLFLYNSHVCEYESIFVFLRNQSSHLQSLSFGVLLERIYFYGKIECLGSVFLKVTDCQANLWLVKEPCMHYVRYQRKCILSSKGTSLFMNKWKCYLATFWQWHFSLWFHPRRISTNPLYNHLLEFVGYLSSARMHPAMVRSQILENSFLINNAIKKVDALIPIMPMVTSLAKAQFCNLLGHPTSKPVWADLSDSNIINRFGHICRNISHYYSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRTFLKTAGSGFLEEFLMSEEDLLCWTFPKASSALWGVYKSRIWHLDIIWINDLANHKKNLRPWK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL29_STAAC
Sequence: MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ERIC3_HUMAN
Sequence: MSHSHPAGLLAAYNSLMDKHLAGYFNNTRIRRHLLRSGLITRSGRILSEKEYKLNMMKRDHQKYIRECLAQAIFHKVLDMERYHQLEIKKKLETLARKERIQRFKGEHTRRSVENNMPILSPHPPVGPKSNRGHSVLVDEGHSSPLALTAPRPYTAPGNMQPPIRLQPLPSNPAVETVPKVTSRSRSKTSLLENEALFPIGGKKAVMKFRNSIGNSQRMNSYQLPNINSYMMPIPPPLPPTGKITRENRSETWRRRRFRPTTAPNGLEPLLTKDSRRIHKTSLHSNAAITMIYLGKNVHLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSLTFFLNGMQVNRLSSCCEYKHRKGSRLGGKRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPKSRKEKSTEKGEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEVLEDDQENTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKDENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPRKSHLPIEESLEIEIEDQEITKADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKDKSKLWEESTAQVKDKKAGLPGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQLVQKTYTLEKKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEAPLRAWKPTAEQPELAEEFTEKREIPPGIERGAEGAAEAEGVRRLGEGGSDPIGQAAAKDAVGLSKDEAPEKQALMLTVLETDKAASEGEQGLEKAVLANEAAALNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEPAKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEILPKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPNEMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEHKDREELSSRENRALKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEGQGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNEGMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQDELVGKTAAAGKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGALERKTSGLGQEQEEGSEGQEAATGSGDGRQETGAAEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQQHMVQGESETADVSPNNVQV
What are the official names of this protein?
Glutamate-rich protein 3.
Protein: RS4_ICTPU
Sequence: MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEVKKICMQRFIKVDGKVRTDITYPAGFMDVISIEKTGENFRLIYDVKGRFTVHRITNEEAKYKLCKVKKILIGTKGIPHLVTHDARTIRYPDPMIKANDTVRIDLETGKITEFIKFDTGNLCMVTGGANLGRIGVITNRERHPGSFDVVHVKDSTGNSFATRLSNIFVIGKGNKAWVSIPRGKGIRLTIAEERDKRLAAKQSSS
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: BCNGR_LACPA
Sequence: GNVAELTEVR
What is the function of this protein?
Has antimicrobial activity against L. paracasei BGKP20.
What are the official names of this protein?
Bacteriocin BacGR.
Protein: PLPL2_RAT
Sequence: MFPRETKWNISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGACLGEAGANIIEVSKEARKRFLGPLHPSFNLVKTIRGCLLKTLPADCHTRASGRLGISLTRVSDGENVIISHFSSKDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSSTNIHELRITNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQGYRDGLRFLRRNGLLNQPNPLLALPPVVPQEEDAEEAAVTEERTGGEDRILEHLPARLNEALLEACVEPKDLMTTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLPDVPEDIRWMKEQTGSICQYLVMRAKRKLGDHLPSRLSEQVELRRAQSLPSVPLSCATYSEALPNWVRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPDALRMRAPASPTATDPATPQDPSGLPPC
What is the function of this protein?
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (By similarity).  Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone and acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade (By similarity).  Also possesses acylglycerol transacylase and phospholipase A2 activities (By similarity).  Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides (By similarity).  Regulates adiposome size and may be involved in the degradation of adiposomes (By similarity).  May play an important role in energy homeostasis (By similarity).  May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion (By similarity).
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein 2, Adipose triglyceride lipase, Calcium-independent phospholipase A2-zeta, iPLA2-zeta.
What are the subcellular locations of this protein?
Lipid droplet. Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: RS8_THEPX
Sequence: MVMTDPIADMLTRIRNANIARHETVEIPASNMKRAIAMIMLKEGFIKSVEEIDDGKGGILKLTLKYGPNKERVISGLKRISKPGLRVYARHDELPRVLGGLGIAIISTSKGIMTDKEARKAGVGGEVICYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y079_METJA
Sequence: MSEIMHKLEKIREELNSYFLERREEIDIALTSILANEHTVFLGNPGVAKSQLIRAIASHINANYFEKLITRFTTEDELFGPLSIKELKDNDRFVRKTSGYLPTAEIAFLDEVFKANSSILNALLSIINERIYHNGDKIEKVPLISLFGASNELPEENELLAFYDRFLFRKVVRGIRSCENLVKLIKLDEEYKPKTTISIKELRKMQEKANEVDIENIIGYLVDIKKKLSQNHIYISDRRFKKSVKAIKCFAYLNGRREAEIEDLEILRHIFWDDIDDILIVSKVIFDITNKYAEQVLDKAEIIKNLKNELKYIDIKKIGECKKDYNKLIEILCKMAYIRLELKKIRNEAIINKRKTDFIDEVIKETDEFNNYIEGILNEL
What are the official names of this protein?
Uncharacterized protein MJ0079.
Protein: VP1_APRVF
Sequence: MDEILYNDNVMIVNDEETSGDVNNQQLISNETIANIQTRLKQLQVSSDSDLEDYINARKMLIEMLNARKEYIPDVLSSLSVERLKSIDLIVQKLNSCEHSIIEHANILDQLQNEITSLKTENEYIVRLNDINAKKAKLFDDFNAKYEDDVGPLYVYAASEDVRQAAIYLSYMMRMIITFENETIESNFIVSDSLYIGDTILNVTISTDLQLGNRTVNVTMDDISESFVILEREYIELYLTRHVHKILNNTISYSTALVIFKRTVEDISIPSQIVNTVLFQQQISNSVTVKDVSKSLVCDFKIDAETELYILLPTIIPDSYSMDILGNQEFMLYLSDLYAFNLLQEILDVLYIDQLEKGLENEDNRAIEQLTLQNAQSIRYILNTLQYVPLYKPYDILIENGILNSIEYAAPLMYIKNEYISKNITRTSDKYTTDRVIGAHVLSGSNMDSLPNTAFKQKLFMNTQSVLTQENPIYEDTDIIIYAVCVISREYDDTICGSGYTYTTSNMYANRSEFIRMNGCIADSVPVKTSTIVKCTYSLIDANRIGLLYNKTRTNIKINQILICFKNSFAVPTSLNVAMDVKIQCLKKTETLSVTQAKPSQILLENGISYFGIICDISFSSDYVFDGNESINFTLQPNTNISGKKELVMYGRQGGGMQISDMFQHKQDSFEYSIKVGLVCNSTQIGMGQWFEIFSTLIQGEFIGNIDTLRESTIRGISNIYDFTDVREFLHEYKISIVKLSIQCLRAMSAGVQDVIVAYSHALSNIDALILDITVEMNDFSNRLTTLEDKVKDIEKWIQNQIDSQNTTIWGSLLDTFVNLIIATALGYATAGIGVLVTKISVAVLSFTSRALTSIARGLQAAGHKVSTLFKLHITQPFLNGAHSLKLLTQKFNAVQGNLTKYERKYITALELSEANNYAAIAKYLKNLNPEIKLAEAINHKLVYSSRYVNPVFKLGNEVMSTVEINYHGLTAIGKLPQLRTPTKKLLSSDFGTTLMKKNKAPAHAYMVITDVDARSEYDLVTKYILGVSEGFTSTTKHVTAGSFKLQYEFRKHPTTNKTTVSFSTYQDTGYTAEEVKLLFNRYFKNRTNITNANQQWELLSSKFMSLQTSTLNSQRFVLPTSHRTTALYEAFKNTRRFDYNLLTNNCQNFCQDSLNWLENGVINGSLIQHSDQLAIKYVNALRGDLSLI
What are the official names of this protein?
Putative structural protein VP1.
What are the subcellular locations of this protein?
Virion.
Protein: LEU1_HERSS
Sequence: MLTDPSQKYRAIAPVDLPDRRWPSRTLRQAPTWLSTDLRDGNQALFEPMNRERKLRLFHELVRIGFKEIEVGFPAASRIDFETVRHLIDEHLIPDDVTPMVMTQLRADLITETVKSVAGARRVIVHFYNAIAPAWREIVFGMSVPQIITLVEDHIALFRRLTAVHPETEWILQYSPETFCMAELEVSLEVCNAAIRAWDAGPRRRMIINLPTTVEVSTPNVFADQIEWMDRRLERREHLILSVHPHNDRGTAVACAEQAMLAGAQRVEGCLFGNGERSGNVDVVTLALNLYTQGIAPGLDFSDIAALARVAEECTALPIHPRHPYVGDLVFTAFSGSHQDAIAKGFAAQRPDAPWRVPYLPIDPTDLGRTYDSIVRVNSQSGKGGIAFLLQRDHHITMPRRMQVEFSAIVQALADASETELTSEHLWDVFERTYLAPVQASPDFSDRTSLAPALEQRRFIYRSHCLHPHPDGERIVLELADTEGNVRTVEGSGNGPIAATVAALGLALRIDSYEERSLGVGVGADAQALAIVEAALPTVPGSRFGVGRHENITTASIMAVLSAASRFAGEEQGKG
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: VP24_EBOZ5
Sequence: MAKATGRYNLISPKKDLEKGVVLSDLCNFLVSQTIQGWKVYWAGIEFDVTHKGMALLQRLKTNDFAPAWSMTRNLFPHLFQNPNSTIESPLWALRVILAAGIQDQLIDQSLIEPLAGALGLISDWLLTTNTNHFNMRTQRVKEQLSLKMLSLIRSNILKFINRLDALHVVNYNGLLSSIEIGTQNHTIIITRTNMGFLVELQEPDKSAMNRKKPGPAKFSLLHESTLKAFTQGSSTRMQSLILEFNSSLAI
What is the function of this protein?
Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways.  Blocks the IFN-induced nuclear accumulation of host phosphorylated STAT1 by interacting with the STAT1-binding region of host importins.  Alternatively interacts also directly with host STAT1 and may additionally inhibit its non-phosphorylated form.  Plays a role in assembly of viral nucleocapsid and virion budding.  May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding.
What are the official names of this protein?
Membrane-associated protein VP24, Ebola VP24, eVP24.
What is the protein family that this protein belongs to?
Belongs to the filoviridae membrane-associated protein VP24 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and to the plasma membrane where budding takes place (By similarity).
Protein: AROB_PSECP
Sequence: MNTSSTVIKVTGESAANNYDVVVGRGLLGTLPEILGERVRRVLVIHPRALRLTGDTVRDDLESAGFTALTAEIPDAEEGKHIQVAAFCWQVLGQNDFTRSDAIVAVGGGAVTDLAGFVAATWLRGVKVIHMPTSLLGMVDASVGGKTGINTAEGKNLVGAFHPPAAVLADLDTLDTLPRNELISGMAEVVKCGFIADPAILELVEKDFAAVTDPRSETLRELIERAIAVKAKVVSEDLKESGLREILNYGHTLGHAIELVERYSWRHGAAVSVGMMFAAELARSVGRLSDADADRHRSILEGLGLPVTYRRDRWQGLLDGMRRDKKSRGDLLRFVVLDGVAKPGILDVPDTSLLFAAYQEVAS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTM1_MACFA
Sequence: MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLKPEYLEGLPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPKCLDAFPNLKDFISHFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2).  Participates in the formation of novel hepoxilin regioisomers.
What are the official names of this protein?
Glutathione S-transferase Mu 1, GST class-mu 1, GSTM1-1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEG3_MOUSE
Sequence: MYHHEDDTNSDMNSDDDMSRSGRETPPPRPSHAFGSERDLERRGRSRDVEPRDRWPYTRNPRSRLPQRDLSLPVMSRPHFGLDRDDDRRSMDYESRSQDAESYQNVVELKEDKKPQNPIQDNLENYRKLLSLGVQLAEDDRHSHMTQGHSSRSKRTAYPSTSRGLKPMPEAKKPSHRRGICEDESSHGVIMEKFIKDVARNPKSGRARELNERPPPRFPRPNDNWKDSSSSRRESVIQERGYEGSAFRGGFRFNADLASRSRALERKRRYHFDSDERGSGHEHKSCVRKKPFECGAEMRQAMSMGNLNSPSFSESQSIDFGANPYVCDECGRQFSVISEFVEHQIMHTRENLYEYGESFIHSVAVNEVQKGQGGGKRFECKECGETFSRSAALAEHRQIHAREYLAECRDQEDEETIMPSPTFSELQKMYGKDKFYECKVCKETFLHSSALIEHQKIHGRGNSDDRDNERERERDRLRARAREQRERERERERERELGEPFLTCPNFNEFRKMYRKDKIYECKVCGESFLHLSSLREHQKIHTRGNPFENKSRMCEETFVPSQSLRRRQKTYREKLFDFNNARDALMGNSDSSEHQKNRSRRNFFEGRGFEKPFVESQKSHTITRPPENKDDDKPFTISVNPNDKLKFPIMENGSQGKSYERSVIHSLGSAEAQKSHGGLGFSKPRPVAESSTQSSSSIYYPRAHSGGNTYEGKEYKDSIIHSLPAPRPLKRHRANDHIQCDEGGESSIYIPDIINKGRKIPAREDAYEGSSSSNYHTPNVSRAEPPSLSGESHDSKQDVTFSVPSSSVREHQKARAKKKYIEPRNNETSVIHSLPFGELLAGHRRAKFFECQECGEAFARRSELIEHQKIHDRERPSGSRHYERSVIRSLAPSDPQTSYAQERFIQEQVRKFRAFGQRSTTSNNLSVQKIYAQETFNAEEPHDKETHGQKIHDKEPYGKEPSGKEPHGDEPQDKEPLDQEMRSEEPHDDKPHGQEPHDDKPHGQEPHDDKPHGQEPHGDEPHGQEPHGDEPHDKEPIDQEMRSEEPHSEESHGDEPHGEESHGQEKVEDATIQASVSEEHQKDDAGDAIYECQDCGLGFTDLNDLTSHQDTHSRKALVDSREYAHSEVHAHSVSEFEKKCSGEKLYECPKCGESFIHSSLLFEHQRVHEQDQLYSVKACDDAFIALLPVRPRRNCTVERNPAVSGSAIRCRQCGQGFIHSSALNEHMRQHRDNEIMEQSELSDEIFIQGLALTEYQGSETEEKLFECTICGECFFTAKQLGDHHTKVHKDEPYEYGPSYTHASFLTEPLRKHIPLYECKDCGQSFLDDTVIAERMVFHPEREGGSEIVAATAQEVEANVLIPQEVLRIQGSNAEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPDGEAEQPNGEAEQPNGDADEPDGAGIEDPEERADEPEEDVEEPEGDADEPDGADIEDPEEEGEDQEIEVEEPYYNCHECAETFASSSAFGEHLKSHASVIIFEPANAPGECSGYIERASTSAGGAEQADDKYFKCDVCGQLFNDRLSLARHQNSHTG
What is the function of this protein?
Induces apoptosis in cooperation with SIAH1A.  Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage.  Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B.  Plays a role in regulating maternal behavior and offspring growth.
What are the official names of this protein?
Paternally-expressed gene 3 protein, ASF-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RUVB_BRASB
Sequence: MKPPARMVSPERRSDDVGDTALRPQQLSEFVGQQQARANLSIFIEAARKRGEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEVLYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVGATTRAGLLTNPLRDRFGIPIRLNFYTVEELEGIVTRGARVLGVGMTADGANEIARRARGTPRIAGRLLRRVRDFASAANADAIDRAIADHALSALEVDAAGLDAMDRRYLTTIALNYGGGPVGVETMAAALSEPRDAIEDIIEPYLIQCGYLQRTPRGRLLTSHAFRHLGMAEPSRDASQFGLFGSEDDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TTHY_RAT
Sequence: MASLRLFLLCLAGLIFASEAGPGGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTADGSWEPFASGKTAESGELHGLTTDEKFTEGVYRVELDTKSYWKALGISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain.
What are the official names of this protein?
Transthyretin, Prealbumin, TBPA.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS8_COLP3
Sequence: MIDKLAREELVDMVPYQSARRLFASGDNEQANSRTWLNANEAPGQGQYQLSSENINRYPDFQPQALLKAYSNYCNLPVDNILATRGADEGIELIIRSFCRAYQDSVLICPPTYGMYAISAENHGAGIISVPLVNTPEAQCQLDLEGLKQQVGKAKVVFLCSPGNPTGNTLSSAQIKAAIEIFKDSAMVVVDEAYYEYTNKELGAEQVNIKLISQYDNVIILRTLSKAFALAGLRCGFTLSNKAVITLLSKVIAPYPIAAPVAEIASKVLTNDLDVMQARVISANSLREQLSEWLKQQKWCSDVFDSNANFVLFRCNNIDEKNKVFNLLVEHNILIRDQSKQQQLENCLRISIGSEDEIAQLKQLLETL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RR14_AETGR
Sequence: MAKKSLIYREKKRQKLEEKYHLIRRSSKKEISQIPSLSEKWKIHGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HDA12_DICDI
Sequence: MEYNTILNNTSKTRVCYFFDQDVGNYFYGPYHPMKPHRLCLTNNLVLNYGLHKKMHLYKARPADAEDMLKFHSEDYVDFLERVTPENINEWKDVKRFHIGEDCPVFPGLYDYCSIYSGGSIEGALKLNHRMYDIAINWSGGLHHARKDEASGFCYVNDIVLAILELLKFHARVLYIDIDVHHGDGVQEAFYLTDRVMTVSFHKFGGDFFPGTGDIDEIGAKTGKLYSVNVPLADGIDDKNYLNIFKPVIQGVMDYYRPSVIVLQCGADSLRFDRLGCFNLTIKGHAECVRFVKSFNIPTLVLGGGGYTVRNVARCWTYETSVCVDTEVNNELPYNDYIQFYSPDFQLIPDYTGLPFKYENANTKSYLESLRIKILENLRILQWAPSVQIQDVPPDIMPIDFDRDEDSKENMDKRKKKHNDFS
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).  May play a role in the regulation of the timing of gene expression during the development and in the definition aspects of the phenotype that mediate social behavior in genetically heterogeneous groups.
What are the official names of this protein?
Histone deacetylase B, DdHdaB, Type-1 histone deacetylase 2.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NCPP_SALCH
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVDNAQRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSHYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: RHBG_TETNG
Sequence: MADVSTSMRLKLPVVCFILEIILIILFGALVQYDYETDAKEWHNQSHNDYENDFYFRYPSFQDVHVMIFIGFGFLMTFLQKYGFGSVGFNFLIAAFSLQWATLMQGFFHGMHGGKIHVGVESMINADFCTGSVLISFGAVLGKTSPIQLLTMAMFEVTLFAVNEFILLSLLGTRDAGGSMTIHTFGAYFGLMVTRILYRPHLDKSKHRNSSVYHSDLFAMIGTIYLWMFWPSFNSAITAHGDDQHRTALNTYYSLAACTLATYGMSAVTSHDGKLDMVHIQNAALAGGVAVGTAGEMMLTPFGSMIVGFLAGIISVLGFKFLSPILESKLKIQDTCGVHNLHGMPGVLGAIVGAVTAALATMDVYGKGMEDVFPAVADGSIDASKQGGVQALSLAITLGIALLGGLIVVFGTPPDTLCFEDGVYWEVPESEAPHEAQLTTVRTEETEKLSS
What is the function of this protein?
Functions as an ammonia transporter.  May play a role in the elimination of ammonia in the gill (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type B, Rhesus blood group family type B glycoprotein, Rh family type B glycoprotein, Rh type B glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.