PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_ECOBW
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y146_MYCPU
Sequence: MSIGLAVGLIVGLSILFFIIGGVVAFFVTRRLFQKQLKENPPINEKMIRAMFLQMGVKASESRIRQVMRSMQQAK
What are the official names of this protein?
UPF0154 protein MYPU_1460.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTCU_HELPO
Sequence: SGRGKNCGGACNSNPCSCGNDCKCGAGCNCDRCSSCHCSNDDCKCGSQCTGSGSCKCGSACGCK
What is the function of this protein?
The metallothioneins are involved in the cellular sequestration of toxic metal ions and regulation of essential trace elements.  This isoform binds exclusively copper.
What are the official names of this protein?
Copper-metallothionein, Cu-MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 2 family.
Protein: Y3760_MYCTU
Sequence: MTSNPSSSADQPLSGTTVPGSVPGKAPEEPPVKFTRAAAVWSALIVGFLILILLLIFIAQNTASAQFAFFGWRWSLPLGVAILLAAVGGGLITVFAGTARILQLRRAAKKTHAAALR
What are the official names of this protein?
Uncharacterized membrane protein Rv3760.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARPIN_DANRE
Sequence: MSRIYDNTALLNKPVHNEKLSFTWDPIVHQSGHGVILEGTVVDFSRHAITDVKNRKERYNVLYIKPSRVHRRKYDSKGNEIEPNFSDTKKVNTGFLMSSYKVEAKGETDCLDERQLREIVNKEQLVKVTIKHCPREAFAFWISEAEMDKTELEPGQEVRLKTKGDGPFIFSFAKLDSGTVTKCNFAGDENAGASWTEKIMANKSNQENTGKSAAQGEGADDDEWDD
What is the function of this protein?
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors (By similarity).  Involved in steering cell migration by controlling its directional persistence.
What are the official names of this protein?
Arpin.
What is the protein family that this protein belongs to?
Belongs to the Arpin family.
What are the subcellular locations of this protein?
Cell projection, lamellipodium.
Protein: SURE_PSEP1
Sequence: MRILISNDDGVTAPGIAALHAALVDYAECAVIAPDQDKSGASSSLTLDRPLHPQTLANGFISLNGTPTDCVHLGLNGLLPQTPDMVVSGINLGANLGDDVLYSGTVAAALEGRFLGGTSLAFSLLSRQPDNLPTAAYIARRLVEAQSRLVLPPRTVLNVNIPNLPLEHIRGIQLTRLGHRARAAAPTKVVNPRGKEGYWIAVAGDAEDGGPGTDFHAVMQGYVSITPLQLDRTFNDAFEQLDGWLEGLL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STAHJ
Sequence: MLDIKLFREQADTVKSKIELRGDDPKVVDEVLELDNERRQLIGKTEEMKARRNKVSEEIAEKKRNKENADDVIKEMRELGDEIKENDAKLNEVDNKVRDILIRIPNLIAEDVPQGDSDEENVEVKKWGTPREFDFEPKAHWDLVEELKMADFERAAKISGARFVYLTKDGALLERALMNYMLTKHTTQHGYTEMMTPQLVNADTMFGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRDEIIQPGVLPEKFTAQTACFRSEAGSAGRDTRGLIRLHQFDKVEMVRIEKPEDSWDALEDMTQNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYDNYKEISSCSNCTDFQARRANIRFKRDAASKPELAHTLNGSGLAVGRTFAAIVENYQNADGSITIPEALVPFMGGKTEIRPVND
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT_LITMO
Sequence: MDPCECAKTGTCNCGGSCSCTNCSCTSCKKSCCSCCPAGCSKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: HIS1_SACS2
Sequence: MVRNLKIAIPNKGRLQQPTLQFLQSVGIKPLASDDRALIVPTSWEGVQLVMIRTEDIPNIVETGATELGITGHDYVIESSADVEELIKLDFGRSKIVLAVPQTWRENSVDELKGKEFRVATKYYNIAKEYVRRRELNAKVVKISGAAEVMPSLGAAEAIIDVMSTGTTLKLHGLKAIDVIMDSYAVVIGNRNWIKNDEADRINLLLTMMKGAIAAKGKKMIFMNVPDNKLDGVINSLPAMLAPAITRLSRSDIWEVITVAEEDILPEVIAKVKAAGARDIVVIDIEKVVK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSC_CHRAM
Sequence: KVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCHIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVNAWTRGCRL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIG_ALKEH
Sequence: MTDPATDTTRRNVHDHEVAKFDAAASRWWDPQGECKPLHDINPLRLDYVAQCLGGLEGRRILDVGCGGGLLAEGMARRGAEVTGIDMSKAALQVARLHALEMEVEVAYRQITVEELADSDEPRFDAVTCLEMLEHVPDPASAVHACARLVKPGGHVIFSTLNRNPKSYLFAILGAEYLLQLLPKGTHDWQQFIRPSELDRWAREADLVLRSMKGLTYNPLNQRYKLTDDTSVNYLAHYQHSPARAGS
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: DNAA_CAMFF
Sequence: MLADEVIELLGQEISKNEMENYISQIKFNEKSSNSENIIFTAPNELVTKFIQTRYANKIANIFEVKTGIKPVISITTQKNRVSIKAKDIDVKQIRTQSSLLNPSYTFESFVVGDSNQFAYISSQQAAQNPGKVYNPLFIYGSTGLGKTHLLQSIGNYCLEHGKTVICVTSEQFMSDFIRNVENRTMNKFKEKYRNCDILLIDDIQFFHKSEKTQEEFFHTFNEIHAKKGQIVMTSDKPPKMLKGFEERLKSRFEWGLMADITPPELDTKIRIIKAKCEFDGINLSSDIIEYIATNMGDNIREIESAIININAFANIMRQEITLEFAKNVIKDQIKEKKDNISLENIISCVSHEMNIKPSDIKSKSRTKGIVEARRICIYLAKTLTPNSMPQLATHFGLKDHSAVSHNIKKINEIINNDGYFKARVEELKNKITSKE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_THEMA
Sequence: MNISTIVSNLKDLILEVRAPYDLEITGVSNHSSKVKKGDLFICRRGEKFDSHEIIPEVMEKGAVAVVVEREIDLDFPYIQVFDSRYFEAKVASLFFEDPWKDVLTFGVTGTNGKTTTTMMIYHMLTSLGERGSVLTTAVKRILGNSYYDDITTPDAITILSAMKENREGGGKFFALEVSSHALVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDDGVAVLNESLADAFNRKSRKITFGTSKNADYRLGNIEVSWEGTQFVLETPDGLLKVFTRAIGDFNAYNAAAAIAALHQLGYDPKDLASSLETFTGVEGRFEVVRGAKKIGLNVVVDFAHSPDALEKLLKNVRKISQGRVIVVFGAGGNSDRGKRPMMSEVASKLADVVILTTDDPRGEDPEQIMEDLIKGIDKRKPYLVLFDRREAIETALTIANRGDSVVIAGRGHERYQIIDEEKKVPFQDREVVEEIIRDKLKGRKYAQ
What is the function of this protein?
Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.  Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase, D-lysine-adding enzyme, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:LD-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKKB_RAT
Sequence: MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQVTGEQIAIKQCRQELSPKNRDRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSSPFPNNLNSVLAERLEKWLQLMLTWQPRQRGVDPQYGPNGCFRALDDILNLKLVHILNMVTGTIHTYPVMEDESLQSLKTRIREDTGILETDQELLQEAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLFDNSKMSYETQITPRPQPESVSCVLQEPKRNLSFFQMRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYREQTEFGITSDKLLLAWREMEQAVEQCGRENDVKVLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQDMVRLLLQAIQSFEKKVRVIYSQLSKTVVCKQKALELLPKVEEVVRLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGHLMSQPSSACDSLPDSDKKSEELVAEAHALCSRLESALQDTVKQQDRSFTTLDWSWLQMEDEERCGLEQACD
What is the function of this protein?
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses.  Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues.  These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome.  In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis.  In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE.  IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs.  Phosphorylates FOXO3, mediating the TNF-dependent inactivation of this pro-apoptotic transcription factor.  Also phosphorylates other substrates including NCOA3, BCL10 and IRS1.  Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation (By similarity).  Phosphorylates RIPK1 at 'Ser-25' which represses its kinase activity and consequently prevents TNF-mediated RIPK1-dependent cell death (By similarity).  Phosphorylates the C-terminus of IRF5, stimulating IRF5 homodimerization and translocation into the nucleus (By similarity).
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB, Serine/threonine protein kinase IKBKB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
Protein: RL21_THEVB
Sequence: MAYAIIETGGKQLRVEPGRFYDVERLPIEPEGTIDLEQVLLVQTDSQVHVGQPYVSGAVVSGTVMEHRRGPKVIVYKMRPKKKTRRKKGHRQELTRIMINEIRLNGESLGG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: COAD_TOLAT
Sequence: MRQKVVFPGTFDPLTSGHFDLINRASILFDEVILAVAASPGKRPLFSLEERLALAKEVCQSLPNVTITGFSNLLIDFMKEQQATILLRGIRTGSDFEYESQLAAMYRRMMPEMEIIFLPPAEQYAFVSSTLVREIALHGGDAGQFVTPNVAEAIKAKQLQLAQS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_XYLFA
Sequence: MDDVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDYMANLIVAQLLFLEAENPEKDINIYINSPGGVVTAGMAIYDTMQYIKPAVSTICVGQAASMGALLLASGASGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILALRARLNEILAKHTGQSLETIAHDTERDNFKSAVDAQAYGLVDQVLGQRPEELIQSS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_MYCS5
Sequence: MFKFVKSSSDYTNWYFHKNSEIAFWGRSNVGKSSLLNALTSKGLAKVSKTPGRTQLINFFENELNQVYVDLPGYGYAKLSKDLKDKMMAMIEEYLLNRSNLKMLYLLIDSRLGFTKIDLEILSFLKENNLNYFIVFTKIDKLNTKEKNELNKKIKTYLEKESFNYLIVSSETKYQIDKLKENINSNF
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: MOAA_SULIN
Sequence: MIDRFGRPLEDLRITLTHVCNFECFFCHMEGEEGDNYILSKEDILLVAKVAKNFDINSVKLTGGEPTLRRDLVEIVRGLKQLGYRDVSMTTNGLLLKDLAYKLKLAGLDRINVSLHAISRETFKKITGVDAFDRVIEGIKSAIDVGLVPVKLNFVVNRRNREEVFKFIELSQNLGVNEIHLIELHPVGLGKLAFKEHDDLREIEEYIEKISIKKQIRKKHFRPRYVLPSGLIVEVIKPYANPIFCAGCNRIRLSVDGKLKTCLYREDNVIDILDILKGEYSEDVKEELLGRAFMIAIAIREPNFKYKI
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RBGA_BACP2
Sequence: MTIQWFPGHMAKARREVTEKLKLIDIVFELTDARIPMSSRNPMIEEILQNKPKIMLLNKADKADPRVTKEWQAHFEQQGVRSLAINSVDGQGLNQIITTSKEILKEKFDRMKAKGVKPRAIRALIIGIPNVGKSTLINRLAKKNIAKTGDRPGITTSQQWVKVGKEMELLDTPGILWPKFEDEKVGLRLAVTGAIKDSIINLQDVAVYGLRFLEENYPERLKKRYDLTDIPEDTAELFDAIGTKRGCLMSGGFINYDKTTEIIIRDIRTEKFGPLTFEKPES
What is the function of this protein?
Essential protein that is required for a late step of 50S ribosomal subunit assembly.  Has GTPase activity that is stimulated by interaction with the immature 50S ribosome subunit.  Binds to the 23S rRNA.  Required for the association of ribosomal proteins rplP and rpmA with the large subunit (By similarity).
What are the official names of this protein?
Ribosome biogenesis GTPase A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PONAB
Sequence: MNESLFTPFITPTVLGLPAAVLVILFPPLLIPTSKHLINNRLIIIQQWLIRLILKQMMTTHNAKGRTWSLMLTSLIIFIASTNLLGLLPYSFTPTTQLSMNLAMAIPLWASTVAMGLRFKAKITLTHLLPQGTPTPLIPMLIIIETVSLFIQPLALAVRLTANITAGHLLMHLIGSSALAMLAINLPLTLITLTILTLLTILETAIALIQAYVFTLLVSLYLHDNS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FABD_HAEIN
Sequence: MKKFAMVFPGQGSQTVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTWQTQPALLAASVAIYRVWKEKFPQLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGKLMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEGEVVSAVNFNSPGQVVIAGAKAAVERAAALCKEAGAKRALPLAVSVPSHCALMKPAAEQLAVTLENIQINTPTISVLNNVDVKAETEGTEIRTALVRQLYSPVRWTETVEKMAQDGVLVLAEVGPGKVLNGLTKRIVGDLQAISVNDVASFNAVEEFLV
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: QUEA_PROM4
Sequence: MLVNSQDLSLSSYDYELDSKLIAQKPLNPRHDARLMVVSKDNGPNLCVSHLKVWNLLDELRAGDLLVINNTRVLKARLRVRLKSGAMAELLLLEPHGDGRWLCLAKPAKKFLPGDYVWMEALEQESLKLQVLTKDLETGGRIVQFPQEFSNRKSIENLLERYGEVPLPPYIRQHDPSDADRYQTRFASTPGSVAAPTAGLHLSDEILNALIQRGIEKASVTLHVGLGTFRPIEEEDLTNLKLHSEWVEVGEEVVSAVQACRSRGGRIFAVGTTTVRSLEASFLLGGGSMKAFQGLVDLVIKPGYQFGVVNGLLTNFHLPKSSLLLLVSALIGRERLLELYQEAIERKYRFFSYGDAMFITPEAVLPGAKSPRVLQ
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPM1H_HUMAN
Sequence: MLTRVKSAVANFMGGIMAGSSGSEHGGGSCGGSDLPLRFPYGRPEFLGLSQDEVECSADHIARPILILKETRRLPWATGYAEVINAGKSTHNEDQASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNKLS
What is the function of this protein?
Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.
What are the official names of this protein?
Protein phosphatase 1H.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CRCB_SYNC1
Sequence: MHLVYIAIFGALGCLSRFMVSGWVYALIGRALPYGTLAVNVIGSLLLGLLMEGGLRSAALPADIRMGITTGFMGGFTTFSTFSYETVRLLEDGSMVAAGANILLNVTVSVVFAGLGIFLARQL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACDH_STUST
Sequence: MSKKLKAAIIGPGNIGTDLVMKMLRSEWIEPVWMVGIDPESDGLKRAREFGLKTTAEGVDGLLPHVLEDDIRIAFDATSAYVHAENSRKLNELGVLMVDLTPAAIGPYCVPPVNLKQHVGTLEMNVNMVTCGGQATIPMVAAVSRVQPVAYGEIVATVSSRSIGPGTRKNIDEFTRTTAGAIEQVGGAKEGKAIIVVNPAEPPLMMRDTIHCLTETEPDQDAITASVHAMIAEVQKYVPGYRLKNGPVFDGNRVSIFMEVEGLGDYLPKYAGNLDIMTAAALRTGEMFAEEIASGTIQLPRREAALA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: MENH_YERPN
Sequence: MTTLACRKLAPHPESPRHQHAGPWLVWLHGLLGSGQDWLPVAQLCGDYPSLLIDLPGHGQSVSLSADGFADISRQLSQTLQANGIREYWLAGYSLGGRIAIYHACYGRHHGLQGLLVEGGNLGLENAELRQARLQQDRQWAQRFRQEPLPQVLDDWYQQAVFADLDPQQREQLVLLRADNHGLAVAEMLEATSLGHQPWLLPALQRLNVPYTYLCGDRDHKFLQLAQQYRLPLHTLARAGHNAHRANPGAFAAQVLAFLSQSSCLPPSSLSR
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: ASSY_SACEN
Sequence: MSKVLTSLPVGQRVGIAFSGGLDTSVAVAWMRENGAVPCTYTADIGQYDESDIASIPGRAEAYGAEISRLVDCREALVEEGLAALSCGAFHIRSGGRTYFNTTPLGRAVTATLLVRAMLADDVLIWGDGSTFKGNDIERFYRYGLLANPRLRIYKPWLDTAFVGELGGRKEMSEWLQERDLPYRDSAEKAYSTDANIWGATHEAKKLEHLDTGIEIVDPIMGVPFWDDSVEIATEDVTLSFVQGRPVAINGKEFDSPVDLVHEANAVGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLFIAYERLVNAIHNEDTIASYHNEGRRLGRLMYEGRWFDPQSLMLRESLQRWVGSAVTGEVTLRLRRGEDYSILDTTGPAFSYHPDKLSMERTEDAAFGPVDRIGQLTMRNLDIADSRAKLENYAQLGLVGQAQAELVGSLQSGGAEAIASVGTHEESDAGALDRAAMESGTD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_STRPF
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_DEHMB
Sequence: MYQSPRGTEDILPEDQPYWHFVRQQAARIAALYGYQRTDTPVFEDAGLFVRSVGEGTDIVSKEMYTFEDRGGDKLTLRPEGTAPVCRAYLEHGMQTRTKPVKLYYLSSIFRYDRPQAGRYRQHHQFGFEAIGEADASLDAEIIEMAWSFYNLLGITDLSLELNSIGCRQCRPNYISALKDYYQQHAGKLCPDCNTRLDKNTLRLLDCKRAECQAVAGNAPRSADYLCPDCLAHYSRLKECLTILDLPFHENFRLVRGLDYYSRTVFEIQPMAEGAQSTIGGGGRYDGLIEQLGGEATPAMGFATGIERIILNLKRQGIVPSPLPSPAVFLAYMGETASLASFALASDLRKAGIGIYQTYAQKSIKAQLRQANSLGVDWVVILGEEELKQGCAVLRNMKEAGQANIPLDQLICEIKKQI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.