PharMolix/UniProtQA huggingface dataset:
Protein: U520_CAEEL
Sequence: MADELARIQQYEYRQNSNLVLSVDYNLTDRRGREEPTGEVLPITDKEMRKMKMGDRAIKGKAPVQDQKKKRKKKDDEKAQQFGRNVLVDNNELMGAYKPRTQETKQTYEVILSFILDALGDVPREVLCGAADEVLLTLKNDKFRDKEKKKEVEALLGPLTDDRIAVLINLSKKISDFSIEEENKPEGDGDIYENEGVNVQFDSDEEEDDGGMVNEIKGDSEEESEEEEGVDTDYTATLKGDGHLTEDEQKARGILHPRDIDAHWIQRSLAKYFKDPLIAQQKQTEVIGILKNAADDRDAENQLVLLLGFDQFEFIKCLRQNRLMILYCTLLRQANEKERLQIEDDMRSRPELHPILALLQETDEGSVVQVEKSKRDAEKSKKAATAANEAISAGQWQAGRKMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHVPALKPRPFAEGEKLVSVSELPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHDDRGPVLESIVVRTIRQMEQNHDECRLVGLSATLPNYQDVATFLRVKPEHLHFFDNSYRPVPLEQQYIGVTEKKALKRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSELQYYLSLMNQQLPVESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGITHEQARADPLLEQRRADLIHTACVLLDKAGLIKYDKRSGIIQATELGRIASHFYCTYESMQTYNKLLVETCSDIDLFRIFSMSSEFKLLSVRDEEKLELQKMAEHAPIPIKENLDEASAKTNVLLQAYISQLKLEGFALQADMVFVAQSAGRLFRALFEIVLWRGWAGLAQKVLTLCKMVTQRQWGSLNPLHQFKKIPSEVVRSIDKKNYSFDRLYDLDQHQLGDLIKMPKMGKPLFKFIRQFPKLEMTTLIQPITRTTMRIELTITPDFKWDEKVHGSAEGFWIFIEDTDGEKILHHEFFLLKQKFCSDEHVVKMIVPMFDPMPPLYYVRIVSDRWIGAETVLPISFRHLILPEKYPPPTELLDLQPLPISAVTNKEFQTVFAESGFKVFNPIQTQVFRTVFESNENVIVCAPNGSGKTAIAELAVLRHFENTPEAKAVYITPMEDMATKVYADWKRRLEPAIGHTIVLLTGEQTMDLKLAQRGQLIISTPERWDNISRRWKQRKSVQNVKLFIADDLHMIGASNGAVFEVVCSRTRYISSQLESAVRVVALSSSLTNARDLGMWLGCSASATFNFMPSTRPVPLDLEIKSFNLSHNASRFAAMERPVYQAICRHAGKLEPKPALVFVPVRRQTRPVAVALLTMALADGAPKRFLRLAEHDDTFQALLADIEDESLRESVSCGVGFLHEGTAPKDVHIVQQLFESNAIQVCVVPRGMCYQIEMSAYLVVVMDTQFYNGKYHVYEDYPIADMLHMVGLANRPILDSDAKCVVMCQTSKRAYYKKFLCDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAIDYLTWTLLYRRMTQNPNYYNLQGTTHRHLSDALSELVELTLKDLENSKCIAVKDEMDTVSLNLGMIASYYYISYQTIELFSMSLKEKTKTRALIEIISASSEFGNVPMRHKEDVILRQLAERLPGQLKNQKFTDPHVKVNLLIHAHLSRVKLTAELNKDTELIVLRACRLVQACVDVLSSNGWLSPAIHAMELSQMLTQAMYSNEPYLKQLPHCSAALLERAKAKEVTSVFELLELENDDRSDILQMEGAELADVARFCNHYPSIEVATELENDVVTSNDNLMLAVSLERDNDIDGLAPPVVAPLFPQKRKEEGWWLVIGDSESNALLTIKRLVINEKSSVQLDFAAPRPGHHKFKLFFISDSYLGADQEFDVAFKVEEPGRSNRKRKHEKEED
What is the function of this protein?
Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome (By similarity).  Plays a role in pre-mRNA splicing (By similarity).
What are the official names of this protein?
U5 small nuclear ribonucleoprotein 200 kDa helicase, BRR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GP15L_MOUSE
Sequence: MRLLALSGLLCMLLLCFCIFSSEGRRHPAKSLKLRRCCHLSPRSKLTTWKGNHTRPCRLCRNKLPVKSWVVPGALPQI
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec. , and Mycoplasma hominis and lentivirus.
What are the official names of this protein?
Protein GPR15LG, Protein GPR15 ligand, Protein GPR15L.
What are the subcellular locations of this protein?
Secreted.
Protein: Y039_SYNY3
Sequence: MANSPQCLLVGSLEPYSGKSGIILGLARLLQQQGMAIAYGKPIGTAMNKAAAALEEADIEFISQSLELAPAQVRKPLVFLDEKTITRRLQGQDQTNYAEALEASIQGLTADLVLLEGPGNLWEGSLFGLSFSELAAKINAAVLLVGRYHSPLVVDGLLKARQTLGDSLKGVVINDIPLEALPETKDLVKPFLESHGIAVLGLLAEDRLLRSVSVRELAHQLNAKVLCSEEHLDLMVESLTIGAMNVNSALEYFRQGENKAVVTGGDRTDLQLAALETSTSCLILTGHAGPQPLIISRAQDLEIPILSVDQDTLTTVEIVDQAFGNVRLQEPVKVQCIQQLIATHFDLQAFQEIMAKG
What are the official names of this protein?
Uncharacterized protein slr0039.
What is the protein family that this protein belongs to?
To A.fulgidus AF1212.
Protein: YIM1_YEAS6
Sequence: MSDEIVTNKSVTYVNNTTPVTITSSELDLRSCYQDDEVVIEVHAAALNPIDFITHQLCNSYIFGKYPKTYSRDYSGVIIKAGKDVDNRWKVGDKVNGMYSHIYGERGTLTHYLILNPAKDIPITHMVEVPKDENDPYDDFVYAAAWPLTFGTAFSTLYDFKKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIERNKKLGYDYLVPYDEGSIVENVKKLKQIVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAKNSFYVTIAGNNKANYKNISWRDFVSLSSILKAINPFKKYNWRFGHPYPPNNFIEVGNEMIKKGTYKPPIDSVYEFDQYKEAIDRLMSNRAKGKVVVKMK
What are the official names of this protein?
Protein YIM1.
What is the protein family that this protein belongs to?
Belongs to the YIM1 family.
What are the subcellular locations of this protein?
Lipid droplet. Mitochondrion.
Protein: KITH_STAAW
Sequence: MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHDLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMFA_PROMH
Sequence: MKLSKIALAAALVFGINSVATAENETPAPKVSSTKGEIQLKGEIVNSACGLAASSSPVIVDFSEIPTSALANLQKAGNIKKDIELQDCDTTVAKTATVSYTPSVVNAVNKDLASFVSGNASGAGIGLMDAGSKAVKWNTATTPVQLINGVSKIPFVAYVQAESADAKVTPGEFQAVINFQVDYQ
What is the function of this protein?
Major structural component of PMF fimbriae.
What are the official names of this protein?
Major fimbrial subunit.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: SPIC_MOUSE
Sequence: MTCCIDQDSLGQTFQDAIDILIQQSAGESQYSSENRNYMAIINPYPHVRGNANYYGMSPTENPLYDWRGVTNGSADLYLEGGFHQSVQNIAESQLVQPPFFQQKGGRGRRKLRLFEYLFESLCNSEMVSCIQWVDKARGIFQFISKNKETLAELWGQRKGNRKPMTYQKMARALRNYARTGEIIKIRRKLTYQFSEAVLQRLAPANYLGKDLFYPQYGQPDQGYLSLNHWNANHYAHGSYQS
What is the function of this protein?
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis.  Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.  Regulates VCAM1 gene expression.
What are the official names of this protein?
Transcription factor Spi-C, Pu.1-related factor, Prf.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: K2C8_POTTR
Sequence: QRTLKVSSSGPRSFSSRSFSSGPSSRISSSSYSRVGSNSSFRSGVGFGPNYGMGLGSSIGVGGITAVSVNQSLLNPLKLELDPSIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKILETKWSFLQQQKTSQSNLDGLFEKYITNLRRQLDSMGQEKLKLEVELGNMQGLVEDFKKKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRHLYEEEIKEMQSQISDTSVVVSMDNSRSLDLDGIIADVRAQYEEIANRSRAEAETMYQIKYEELQLLAGKHGDDLRHTKTEISE
What is the function of this protein?
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Protein: RL20_SYNAS
Sequence: MSRVKRSVTAKKKRRKIFKLAKGFFGARSRLLRTATEAVNRALNYAFRDRRVRKREFRKLWIARINAASRAQGLTYSRLIDGLRKSHVEIDRKVLADIAVNDPRGFSEIVLLAKGETVS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PALH_EMENI
Sequence: MEDDGRLAPRQIWARPTSTTTRSYVPGCTPFLLPSDGYVYLNRTYSISLGENAIYDPACTSTPTTTEHAGAALDIHDPFYASVTPLLYAMGCATVVSYLLVIILLITPRTFYVGGPGGGANFLGRHGMVSGSYSNNSSVVGVGGRPWLQKVAALLVAISLTIATADSFRVAEKQYDHGYSDAEALTSEVIDGTEIKVVRIISSTFLWLAQVQTLIRLFPRHKEKVMIKWAGFALIVLDTIFAILDKFLVKTNTTRPRLYEDAIPALSYLFELALNLLYAAWVIFYSLSKHRFAFFHPKMRNICLVALLSLCAVLIPVVFFVLDIAKPEIAGWGTYIRWVGSAAASVVVWEWVERIEALERDERKDGILGREVFDGDEMIEVTPSEEVDWPRQQFHGHDRGGGTGMSSAWGGVMGLAHRPLRPRGGRITQTQREAEGATAAKSRKRRSARPTPPPAAVTPVSRADTTSAASTVYNVHYYPVSSPTPPVAMPFMEEEDEGSDGDGEKELAVVQNQQSSLPTQDTYTEPRRQNSPQIVNVDNRWRFILNPFKNRHAALPREVASAQAEEEGFLSPDDQAPRQGDEENPHYTPRHRGLFSFHPMSDGASRRQSGADQPLPVTVIPARRRGQDTWSPQWFTNSNLVDRSSSRRTASRPRDQRMKVIQPQVQSAAPWTAADMEASFSSMDYELRYDPEAAALVSEDIPDHHSQPTQADSPAHPTMSGGNGPSGGETQSALDTGPGIEGSVNEGSVIEGPEESHSQR
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.  Might be a pH sensor.
What are the official names of this protein?
pH-response regulator protein palH/RIM21.
What is the protein family that this protein belongs to?
Belongs to the palH/RIM21 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AACT1_ARATH
Sequence: MAPPVSDDSLQPRDVCVVGVARTPIGDFLGSLSSLTATRLGSIAIQAALKRAHVDPALVEEVFFGNVLTANLGQAPARQAALGAGIPYSVICTTINKVCAAGMKSVMLASQSIQLGLNDIVVAGGMESMSNVPKYLPDARRGSRLGHDTVVDGMMKDGLWDVYNDFGMGVCGEICADQYRITREEQDAYAIQSFERGIAAQNTQLFAWEIVPVEVSTGRGRPSVVIDKDEGLGKFDAAKLKKLRPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGLHVIAKIRGYADAAQAPELFTTTPALAIPKAIKRAGLDASQVDYYEINEAFSVVALANQKLLGLDPERLNAHGGAVSLGHPLGCSGARILVTLLGVLRAKKGKYGVASICNGGGGASALVLEFMSEKTIGYSAL
What is the function of this protein?
Catalyzes the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA.
What are the official names of this protein?
Acetyl-CoA acetyltransferase 1, Acetoacetyl-CoA thiolase 1, Thiolase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: MSRA_ECO57
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLHGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: Y449_BACCZ
Sequence: MGRKWNNIKDKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALRVVLERAKTYNVPRTIIDRAVEKAKGGSEENYDELRYEGFGPNGAMVIVDTLTNNVNRTAADVRAAFSKNSGNMGVNGSVAYMFDATAVIGLEGKTSDEVLEILMEADVDARDILEEEDAVIVYAEPDQFHAVQSALKDAGVEEFTVAELTMLAQNDVTLPEDAQAQFEKMVDALEDLEDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BCE33L0449.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SINMW
Sequence: MQVIETLAQGLKRELKVVIPADEMEARMNERLVEVKDRVRINGFRPGKVPVAHLKKVYGKSIMADLVNEIVREKPTEILTSRGEKSATQPEIGMTEDEAEADKILKAEADFEFTVAYEIIPPIELKDASGIKVTREVVDVGEDEVNEQIERIAESARTYESKKGKAANGDRVTIDYLGKVDGEAFDGGKDEDAELVLGSNRFIPGFEEQLVGAKAGDEKTITVTFPADYPAANLAGKEATFDVTVKDVAAAAPIEINDELATKLGLESVDKLKEIVRGQIESQFGSITRQKVKRQLLDQLDELYQFDTPERLVDAEFENIWRQINTDLQQAGKTFADEDTTEEEARAEYRKLAQRRVRLGLVLSEIGEKAGVQVSDDEMQNSLFQQLRQFPGQEKEIIEYFRNTPGAAASLRAPLFEEKVVDHLLTEVSVTDKKVSKEELTAEDDADEKPAKKTASKKKAAAKADAAEGEEAAAPKRKAPAKKKASDESAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: YHAM_BACAA
Sequence: MKKKIAEYEVGEQVDVFLLIKTATKGIASNGKPFLTVILQDPSGDIEAKLWDVSPEVEKQYVAETIVKVAGDILNYKGRIQLRVKQIRVANENEVTDISDFVEKAPVKKEDMVEKITQYIFEMRNPNIQRLTRHLLNKHQNEFLDYPAATKNHHEFVSGLAYHVVSMLDLAKAISNLYPSLDKDLLYAGVILHDLGKVIELSGPISTTYTLEGNLLGHISIMVNEIGKAADELQIDAEEVLILQHIVLSHHGKAEWGSPKPPLVKEAEILHYIDNLDAKMNMMDRALGRTKPGEYTERVFALDNRSFYKPSFHN
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: RRP36_FUSV7
Sequence: MAFKRKSTALGLERRVRPRREDRWEEDPESQGSSSEDDDEVEEEGVRGQHNDEDEDEEGSDSEEGSEEEPEPEEQTPKVDLSSISFGALAKAQATLPSTSRRSKSSKTATESSRTETTPAPRKSTRSKDDPKPKRSSKHAPQEQTSKKPVSRRREILPDNRRQYRDPRFDPLVGKVDEEKASKAYAFLDEYREKEMSDLRAQIKKTKDTYAKEDMKRQLQAMESRKKARKRKEEEENLLKEHRKKEKELVAQGKTPFYLKRSEQKKQILVKRYEGMSKGQVDRAIERKRKKVAGKEKKELDWLQGARERG
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PIL1_SCHPO
Sequence: MMNRAYSLRNSRAPTASQLLNPPPPSSSTRSGRLFAPLSHTMRINHAATFTPDLAKRLAVLVKMEKNVMRSMEVTIRGRRDCARQLSYWGEDCDDDISDVTDKLGVLFYEMAELENYLIDRYDQYRMTLKSIRNIESSVQPSREKKQKLLDQIYALKHKDPESPRLVTMEQELVREEAACLVAEAQLSNTTREKFKQAMTFNLDALHEHAEKLNLIATYGRHLLNLIDDTPVTPGEARPAYDGYETSRQIVMDAEHALSSWVPSQPAVNFVKPQIEDDAQSDARSWNEYEAQGEPVPVEQVTHLQDDVQSDTSEIIENEPGMHPHVHAERMSRIASESSDAVPQQTAVQVA
What is the function of this protein?
Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase ksg1/ppk21 activity and regulating their downstream CWI pathways pck2-MAP kinase pathway and protein kinase gad8 pathway.  Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress (By similarity).
What are the official names of this protein?
Probable sphingolipid long chain base-responsive protein pil1, Protein kinase inhibitor pil1.
Protein: KCY_METKA
Sequence: MFSISVVITIGGLPGSGTTTMARRLAEHYGLKHVYAGKIFREMAEERGMDLEEFSKVAEDNPDIDLEIDRRQREAAEEGDVILEGRLAAFVAAGELDHVKGPDLATLKIWLKAPLEVRAERVAKREGIDVEEARRRIQEREKSELKRYKEIYGVDPTDLSLYDLVLDTSRWSEDETFSILKAAIDPLLEREDP
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_PSEPU
Sequence: MSENQTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGSGLHHMVFEVVDNSIDEALAGHCDDITVIIHTDESISVRDNGRGIPVDVHKEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSEKLVLTVRRSGKIWEQTYVHGVPQAPMAVVGESETTGTHIHFKPSAETFKNIHFSWDILAKRIRELSFLNSGVGILLKDERSGKEEFFKYEGGLRAFVEYLNTNKTPVNSQVFHFSVQREDGVGVEVALQWNDSFNENLLCFTNNIPQRDGGTHLVGFRSSLTRSLNSYIEQEGLAKKNKVATTGDDAREGLTAIISVKVPDPKFSSQTKDKLVSSEVKTAVEQEMNKYFSDFLLENPNEAKAVVGKMIDAARAREAARKAREMTRRKGALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRRTQAILPLKGKILNVEKARFDKMISSQEVGTLITALGCGIGREEYNIDKLRYHNIIIMTDADVDGSHIRTLLLTFFFRQLPELVERGYIYIAQPPLYKVKKGKQEQYIKDDEAMEEYMTQSALEDASLHLDESAPAVSGVQLESLVNEFRSVMKTLKRLSRLYPEELTEHFVYLPEVTLEQLGDHAVMQAWLAKLQERLNSSQKSGLAYNASLREDKERNVWLPEVEITSHGLASYITFNRDFFGSNDYRTVVNIGAKLSSLLGEGAYVQRGERRKAIVEFKEGLDWLMNETTKRHTIQRYKGLGEMNPDQLWETTMDPTVRRMLKVTIEDAIAADQIFNTLMGDAVEPRREFIESNALSVSNLDF
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_ANOGA
Sequence: MTKLIIMMMCLIMSFIFMQMKHPLSMGLMLLIQTFLTCLITGIYVKSFWFSYVLFLIFLGGMLILFIYVTSLSSNEMFTMSFKLTMFSLVLFSLSMVIFFILDKTLIEQFIINMEMEKFSMTNNLINENILSLNKMYNFPTNLITLLLINYLFLTLLVTVKITKKFYGPLRPMN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: KMCP1_HUMAN
Sequence: MSALNWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Kidney mitochondrial carrier protein 1, Solute carrier family 25 member 30.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: MIAA_LIMRJ
Sequence: MNKVIAIVGPTAVGKTALSIKLAHEFDGEVISGDSMQVYRRLDIGTAKVTPEEMGDVPHHLIDICNIEERFSAARFKKLADQKIDEIAQRNHLPIIAGGTGFYLQTLTDNLALGSDQFDQQTLDIRNHWKEVAEEKGAEYVWEQLNKLDPVASARIPKSNTRRVIRALEVIKKTGQLFSNQPHFKATNDFLLIGLTTDRPVLYDRINKRVDLMIQNGLLEEAKWLFDQGGEDLPAGKGIGYHELFPYFRGEISLDEAVEKIKQDSRHYAKRQLTWFRNKADTHWFDILRHPDDINQIKQFINDWLKK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MURQ_BACC0
Sequence: MLENLSTEHRNEKTMNLDEMNIKEILQRMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFVKKAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: NUOB_PSEMY
Sequence: MQYKLTRVDPNAPNEAYPIGQRELVSDPLLEDQVHKNIYMGKLEEVLNGAINWGRKNSLWPYNFGLSCCYVEMTTAFTAPHDVARFGAEVIRASPRQADFMVIAGTCFIKMAPVIQRLYEQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAFLQGLMLLQESIGQERRPLSWVVGDQGIYRAEMPSQKEQRREQRIAVTNLRSPDEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOC_MYCTU
Sequence: MLDVNFFDELRIGLATAEDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDEEMRHNELSTLEAEMAVERKAVEDQRDGELEARAQKLEADLAELEAEGAKADARRKVRDGGEREMRQIRDRAQRELDRLEDIWSTFTKLAPKQLIVDENLYRELVDRYGEYFTGAMGAESIQKLIENFDIDAEAESLRDVIRNGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYYLTTEVPGDTGEYQPASGDHPETGVYSSPAEAIMAADRGVLSVRAKIKVRLTQLRPPVEIEAELFGHSGWQPGDAWMAETTLGRVMFNELLPLGYPFVNKQMHKKVQAAIINDLAERYPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPRKKEILDHYEERADKVEKQFQRGALNHDERNEALVEIWKEATDEVGQALREHYPDDNPIITIVDSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPVKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCQTERGIVVELAERAPDGTLIRDPYIETSAYARTLGTDAVDEAGNVIVERGQDLGDPEIDALLAAGITQVKVRSVLTCATSTGVCATCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRGKAPIADVTGRVRLEDGERFYKITIVPDDGGEEVVYDKISKRQRLRVFKHEDGSERVLSDGDHVEVGQQLMEGSADPHEVLRVQGPREVQIHLVREVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLIDRAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNIAVQPTEEARAAAYTIPSYEDQYYSPDFGAATGAAVPLDDYGYSDYR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PROB_LISMH
Sequence: MRESLKNSKRLVIKVGTSTLMYGNGHINLRTIEKLAMVLSDLRNEGKEVILVSSGAIGVGCHKLQLPVRPTSIPDLQAVASVGQSELMHIYSKFFGEYGQVVGQVLLTRDVTDFPISRENVMNTLDSLLSRGIIPIVNENDTVAVEELEHVTKYGDNDLLSAIVAKLVQADLLIMLSDIDGFYGSNPTTDPDAVMFSEINQITPEIEALAGGRGSKFGTGGMLTKLSAASYCMESNQKMILTNGKNPTVIFNIMQGEQVGTLFASKKEELSHDRTH
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTFD_AMYOR
Sequence: MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAAEERLAEVGVPHVPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVAVGDLAAATGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTDIRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPCWPADPVLAPLQPDVDAVQTGAWLLSDERPLPPELEAFLAAGSPPVHIGFGSSSGRGIADAAKVAVEAIRAQGRRVILSRGWTELVLPDDRDDCFAIDEVNFQALFRRVAAVIHHGSAGTEHVATRAGVPQLVIPRNTDQPYFAGRVAALGIGVAHDGPTPTFESLSAALTTVLAPETRARAEAVAGMVLTDGAAAAADLVLAAVGREKPAVPA
What is the function of this protein?
Catalyzes the attachment of L-vancosamine to a monoglucosylated heptapeptide intermediate during the final stage of glycopeptide antibiotic vancomycin biosynthesis.
What are the official names of this protein?
Devancosaminyl-vancomycin vancosaminetransferase, Devancosamine-vancomycin TDP-vancosaminyltransferase, Glycosyltransferase GtfD.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.