PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_SHESM
Sequence: MLAKRIVPCLDVKDGCVVKGVQFRNHEIVGDIVPLAARYAAEGADELVFYDITASAHDRVVDKSWVSRVAEQIDIPFCVAGGIKTIGQARELLAFGADKISVNSPALSDPSLISRLQDEFGRQCIVIGIDSFYDAASDSYKVKQFTGDEAATKETAWYTQDWVEEVQKRGCGEIVLNVMNQDGVRGGYDIKQLSLVRQLCDVPLIASGGAGTMAHFRDVFIEAKVDAALAASVFHKAIINIGELKQYLAAEGIAIRQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB15_RAT
Sequence: MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELDGLRTCASNELALAELEEDEGKTEGPANSSKTCWC
What is the function of this protein?
May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
What are the official names of this protein?
Ras-related protein Rab-15.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RLMB_XANCP
Sequence: MSKQNQWIVGVNAVASSVENDADNVREVLIEAGSKNPRLTEIEEQARRKGIDVRRVNTQALDGVGGQVRHQGVAARYAAARLWAENELEGLVEAAQGRALVLILDGVQDPHNLGACLRSAAAAGVTAVVIPKDKSATVNATVRKTSAGAADRIPVVAVTNLARCLRDLQKQGVWLYGLAGEAEASLYSVDLRGNVGLVLGGEGDGLRRLTREHCDGLVKIPMPGDIESLNVSVATGVTLFEAVRQRLGA
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_SYNS9
Sequence: MMPHQLSLVVGLGNPGSKYDGTRHNIGFMALERLARREGFSFRQQAKLHGLSADKGFGDQRLRLLMPQTFMNDSGRSVRAALDWYGFQPEEIVLLVDDMDLPLGRLRLRAQGSAGGHNGLRSTIQHLGTQVFPRLRIGIGAPAENPAERRARTVSHVLGPFSRAEQPCVDAVLDAVLDGLDRLKTQGMERAGTWINGFRYESPSAT
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1552_ARCFU
Sequence: MVWFRCMRYGEAAIVLSAVLMGTVSVFVRNVGGDTLSVTFLRLFFGFLAVLPFCLRDVGRPDRTLLGLAVFNFLTVASYIAAIQSTEVAMAALLLYMAPVYVIPLSVLMGERVEVKTLLALPLGLIGLYLMLTPYAELTFGIIFGIVSGLSYAIVFVLSKEARKKHSPWRITFYNLGLGSAALLPYFLMFGRVGSWLWAIGLGVVPTAVPFVLFSYGMKYVKVQRAPILALIEPLCAGLVGYFYFGETLTLTQLIGGAMILAGVLIAWRE
What are the official names of this protein?
Uncharacterized transporter AF_1552.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPE_HELAH
Sequence: MTHAFEVYPKVNIFLKILYKEGAYHKLISRMCLVKGQLKDIISVKNAPSFCLKGNFDCPLEENSLFKALQILKNFLKSKKLSHSVIKSLDTLAIEVEKNIPTQAGLGGGSTDAGGLLYHLNQIFDLRLNLEELYTIGSLVGADTNFFISQYKSANATSYGEVIENFEEKPLENRLEIYVPDNIFCSTKAVYQAYKPKTCFYQAKEWLKKPSLECLKTCDRSELNDLLKPALLTHQALKDIESQLGKEWFFSGSGSAFFRLKPTQKGSE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SYL_CARHZ
Sequence: MQERYDFKAIEAKWQKKWEELKLYEVDDFSEKPKYYCLEMFPYPSGKLHMGHVRNYSIGDVVARYKRMRGYAVLHPMGWDAFGLPAENAAIKHGNVHPADWTWDNIANMRRQLKELGISYDWRREIATCHPEYYRWTQWLFLQFYKKGLAYKKKAPVNWCPGCQTVLANEQVIDGECERCHSRVEKKELEQWFFKITAYAERLLQDIKKLTGWPEKVKIMQENWIGRSEGAEITFKIKGHEETISVFTTRPDTIFGVTYMVLAPEHPLVEKISRGTQYEKDVLEFKRKMMYLSEIERTAETAEKEGVFTGAYAINPFTGEEIPILLANYVLVEYGTGAVMGVPAHDQRDFLFAKKYNLPIKVVITPPGQELKAEELTEAYTGEGILVNSGEFTGLANKEAIRIITQEAEKRGFGKYRVNYRLRDWLISRQRYWGAPIPVLYCEKCGIVPVPEDQLPVVLPYNVEFRPTGESPLKYVPEFLNATCPECGGPATRETDTMDTFICSSWYYYRYTSPRDKQQPWSKEKVERWLPVDQYIGGVEHAILHLLYSRFFTKVLYDLGLVHVDEPFTNLLTQGMVLKDGAKMSKSKGNVVSPEEIVEKYGADTARLFILFAAPPERDLEWSDQGVEGSFRFLNRVWRLIYQTKDRISDELREFSAKDKELNRLLHATIKKVTEDIEERFNFNTAISAIMELVNGLYQYKEGEINPGLLKEALNKLVILLAPFAPHIAEELWEALGNKQSVHLEKWPEYDEEALITEEVEIVIQVNGKVKDRVMVPRNAAEDELKEIALNTPKIKELTADKKIIKVIIVPEKLINIVVAG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_HAEIG
Sequence: MAVQQNKKSRSRRDMRRSHDALTTAAVSVDKASGETHLRHHVTADGYYRGRKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ALPK1_HUMAN
Sequence: MNNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRALLPSELRTLIQEAKEMKWPFVPEKWQYKQAVGPEDKTNLKDVIGAGLQQLLASLRASILARDCAAAAAIVFLVDRFLYGLDVSGKLLQVAKGLHKLQPATPIAPQVVIRQARISVNSGKLLKAEYILSSLISNNGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYEAAELIWASIVGYLALPQPDKKGLSTSLGILADIFVSMSKNDYEKFKNNPQINLSLLKEFDHHLLSAAEACKLAAAFSAYTPLFVLTAVNIRGTCLLSYSSSNDCPPELKNLHLCEAKEAFEIGLLTKRDDEPVTGKQELHSFVKAAFGLTTVHRRLHGETGTVHAASQLCKEAMGKLYNFSTSSRSQDREALSQEVMSVIAQVKEHLQVQSFSNVDDRSYVPESFECRLDKLILHGQGDFQKILDTYSQHHTSVCEVFESDCGNNKNEQKDAKTGVCITALKTEIKNIDTVSTTQEKPHCQRDTGISSSLMGKNVQRELRRGGRRNWTHSDAFRVSLDQDVETETEPSDYSNGEGAVFNKSLSGSQTSSAWSNLSGFSSSASWEEVNYHVDDRSARKEPGKEHLVDTQCSTALSEELENDREGRAMHSLHSQLHDLSLQEPNNDNLEPSQNQPQQQMPLTPFSPHNTPGIFLAPGAGLLEGAPEGIQEVRNMGPRNTSAHSRPSYRSASWSSDSGRPKNMGTHPSVQKEEAFEIIVEFPETNCDVKDRQGKEQGEEISERGAGPTFKASPSWVDPEGETAESTEDAPLDFHRVLHNSLGNISMLPCSSFTPNWPVQNPDSRKSGGPVAEQGIDPDASTVDEEGQLLDSMDVPCTNGHGSHRLCILRQPPGQRAETPNSSVSGNILFPVLSEDCTTTEEGNQPGNMLNCSQNSSSSSVWWLKSPAFSSGSSEGDSPWSYLNSSGSSWVSLPGKMRKEILEARTLQPDDFEKLLAGVRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQRNAFWVHHLHQEEILGRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTTNFGKRGIFYFFNNQHVECNEICHRLSLTRPSMEKPCT
What is the function of this protein?
Serine/threonine-protein kinase that detects bacterial pathogen-associated molecular pattern metabolites (PAMPs) and initiates an innate immune response, a critical step for pathogen elimination and engagement of adaptive immunity (PubMed:28877472, PubMed:28222186, PubMed:30111836).  Specifically recognizes and binds ADP-D-glycero-beta-D-manno-heptose (ADP-Heptose), a potent PAMP present in all Gram-negative and some Gram-positive bacteria (PubMed:30111836).  ADP-Heptose-binding stimulates its kinase activity to phosphorylate and activate TIFA, triggering pro-inflammatory NF-kappa-B signaling (PubMed:30111836).  May be involved in monosodium urate monohydrate (MSU)-induced inflammation by mediating phosphorylation of unconventional myosin MYO9A (PubMed:27169898).  May also play a role in apical protein transport by mediating phosphorylation of unconventional myosin MYO1A (PubMed:15883161).  May play a role in ciliogenesis (PubMed:30967659).
What are the official names of this protein?
Alpha-protein kinase 1, Chromosome 4 kinase, Lymphocyte alpha-protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Note=Localized at the base of primary cilia.
Protein: RS3_RUTMC
Sequence: MGQKVNPKGIRLGIVKDWDSKWYANSQDYSKYLLSDIKVRDYLFDKLTNASVSRIQIERLANNAKITIHTARPGIIIGKKGADIEQLKSIVSKMMGIPVHINIEEIKKPELDARLVAENIAQQLEKRVMYRRAVKRVLGNTTRLGAKGIKVMVNGRLNGAEIARSEWYREGRVPLHTFRADVDYSSYGANTQYGVIGIKVWIFKGEILNHKKGTLDEVARRGATNQIAQKIK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PTCD1_RAT
Sequence: MDLLRLSRLFSGPHPIGLSVLQRLDLLRSTQWTGGREGPAWLRAASCSSSSHQKRMSSLCSDSSTPVAPQEEEEEESFGTLSEKFSSRRIFHKSTAQLYNLKLKEQGVEEEELEPRLRQGGRNTPYWYFLQCKRLLKEGKLAEALDLFERQMLKEERLQPLECNYTVLIGGCGRVGYLKKAFRLFNDMKKRDLEPSDATYTALFNVCAESPWKDSALQSALKLRQQLQAQNFQLNLKTYHALLKVAAKCADLRVCLEVFKEIIQKGHAVTEETFCFLLMGCIQDKKTGFRQAMQVWRQMLSLGIKPSRHGYNLLLGAARDCGLGDPEVASRLLLTSQEETILLQPPTGRRLAGGKVQAKTRHGVSVKHVEALERQLFLEPSHKLEGPPAFPEARETSRTQPEVETKAEPGHMGALAPLALKPPDLELQVNLLSLGALSPAVVSFGTVATPADRLALMGGLEGFLGKMAEHRLQPDIKTLTLLAEVVEPGSPAESSLLSILDRHRVEADITFFNTLIRKKSKLGDLEGAKALLPILAKKGIVPNLRTFCNLAIGCHRPRDGMQLLADMKKSQVTPNTHIYSTLINAALKKLDYTYLISILKDMRRNSVPVNEVVIRQLEFAAQYPPTFDRYKEKNTYLEKIDGFRAYYKQWLKVMPAEEPPHPWQEFRDKPVRNQVITENAGGLRDG
What is the function of this protein?
Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity.  Affects also the 3'-processing of mitochondrial tRNAs.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PTCD1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DDL_BEII9
Sequence: MAKHVAVLMGGLSAEREVSLCSGAACAEALRGEGFEVTEVDVDRQIGERLAALRPDVAFNALHGRFGEDGIIQGVLEMLAIPYTHSGVLASALAMRKDRARDVLAAAGVPIAKGVTVDRLEAAQRHILPPPYVIKPLGEGSSFGVFIVREDQAYPPQELTRSDWAFGNRVLVESYIGGRELTCAVIGEKAHDVIEIKAVGGGWYDYDAKYRKGGSIHILPAELKRNIYQNVQLLSLKAHKALGCRGVSRTDFRYDDRPEGTGELIVLEVNTQPGMTETSLLPEIAAYAGLSFGELVRWMVDDASCDR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM9_CHICK
Sequence: MAGQISETDQIKQFKEFLGTYNKITENCFMDCIRDFTTREVKPEEITCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLSQPR
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RGLT_ASPFC
Sequence: MQFDSLPLPPSSSHDTTSVPPLKRHAACDECRKRKLKCSGEATGCSRCLKQSLPCHYSLQKPMGRPPKKRPREDNDASVYEITDNGMWADIDDGGILTEEAGAEATAASDALRLCPPVYTAPMRMPQAFPNLLSTDDSHNHLWQLESGRSLDPIPATTGPWPDFSSVTAATSSPFTLPSSLTLIDSPSVSSPSSDGGNSSQCTCLSYLYLCLSHLSSLAPFPISQHTLCSLFIAAKTARAVIRCEVCPTSFALGMQNVMFTGTLLNVIADAWLRVSQADAEELGKLAAPPAYVASVTQNSPNPAEAWKDWLRQTVRSAITGGPADPAGQVKCSDSPTLLSLIEEMEARQHRWHRTRTVESPNEPGSCSPVSHEDHREEDMLCFRVIRSARDVIAKFEFAPHEYPEGVVPV
What is the function of this protein?
Transcription factor that is involved in protection against oxidative stress (PubMed:32667960).  Binds to promoter regions of the gliotoxin (GT) biosynthetic genes gliZ, gliF, gliT, gliM, gliA and gtmA (PubMed:32667960).  Two related but different DNA motifs (5'-TCGG-3' and 5'-CGGNCGG-3') are specifically enriched among rglT binding sites in GT-inducing conditions (PubMed:32667960).  Also indirectly regulates the expression of gliP, gliG, gliH and gliN (PubMed:32667960).  Plays a key role in resistance against exogenously-added GT and GT biosynthesis, mainly through the direct regulation of gliT (PubMed:32667960).  Furthermore, rglT is important for virulence in chemotherapeutic mice with invasive pulmonary aspergillosis (IPA) (PubMed:32667960).
What are the official names of this protein?
Transcription factor rglT, Regulator of gliotoxin.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_VIBCH
Sequence: MVYSYTEKKRIRKDFGTRPQVLDIPYLLSIQLDSFEKFIEQDPEGQYGLEAAFRSVFPIQSYNGNSELQYVSYRLGEPVFDVKECQIRGVTYSKPLRVKLRLVIFDKDAPAGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYVRIDRRRKLPASIILRALGKTSAEILDIFFEKVNFEVKDQTLMMELVPERLRGETATFDIEADGKVYVEKGRRVTARHIRQLEKDGVNFIEVPVEYIVGKVSAKDYVNEATGELIITANQEISLEALANLSQAGYKKLEVLFTNDLDHGPFMSETLRVDSTTDRISALVEIYRMMRPGEPPTKEAAESLFESLFFSAERYDLSTVGRMKFNSSIGREDAEEQGTLDEVDIIEVMKKLISIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDNVMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHVTHYGRLCPIETPEGPNIGLINSLSAFARCNEYGFLETPYRRVVNGVVTDEVDYLSAIEEGQFVIAQANAKLTEEGGFADELVTARQKGESGLHPREHVDYMDVATNQVVSIAASLIPFLEHDDANRALMGANMQRQAVPTLRSEKPLVGTGIERNVAVDSGVTAVAKRGGVIQSVDASRIVVKVNEEELIPGEAGIDIYNLTKYTRSNQNTCINQRPCVMPGEPVARGDVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSILVSERVVQDDRFTTIHIQELSCVARDTKLGAEEITADIPNVGEAALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPNSVAGTVIDVQVFTRDGVEKDKRALEIEQMQLKEAKKDLTEEFQILEGGLLARVRSVLLAGGYTEAKLGSIERKKWLEQTLENEELQNQLEQLAEQYDELKADFDKKFEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVDIVLNPLGVPSRMNIGQILEVHLGLAAKGIGDKINQMIKEQQELAKLREFLQKVYDLGDTRQRVDISELSDEDVRTLAHNLRAGLPVATPVFDGAPESSIKAMLELADLPASGQLTLFDGRTGDAFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHAMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: REX2_THEMA
Sequence: MAEMIHLPRSTFERLKMYRKVLEATKKPYISSDEIARFLEINPDLVRKDFSYLNCQGKPRVGYDVEELRKELDDLFGVNNTTNMIIVGANDLARALLSLDFSKAGVKVVAVFDTERENVGKFIGEFAVRELDVLERVIRRFDAEIAALCVSKDRAQATAEFLIEKGIKAVWNFTGVHLDLPEGVIVVEEDLTQSLLTIKHLLKK
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex 2.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NM111_ASPTN
Sequence: MDLNGDSNAKRKRSSISAAAERPAKHLRPENSSLTPGDTTPANGTVYDVEDDAESSHLIPIAAAPADSPEWQATIEEVVKSVVSIHFCQTCSFDTELSMSSQATGFVVDAERGYILTNRHVVCPGPFWGYVIFDNHEECDVRPVYRDPVHDFGILKFDPKAIRYLKLTELKLQPDAARVGSEIRVVGNDAGEKLSILSGVISRLDRNAPEYGEGYSDFNTNYIQAAAAASGGSSGSPVVNIDGHAIALQAGGRADGAATDYFLPLDRPLRALNCIRRGEPVTRGTIQTQWILKPFDECRRLGLTPEWEAKVRKAAPTETSMLVAEIILPEGPADGKLEEGDVLLQVNGELLTQFIRLDDILDSSVGKTVRLLVQRGGQNVELECEVGDLHAITPDRFVTVAGGTFHDLSYQQARLYAIATRGVYVCEAAGSFKLENTLSGWLIDSVDKRPTRNLEEFVEVMKSIPDRSRVVISYRHIRDLHTRGTSIVYIDRHWHPKMRLAVRNDETGLWDFSDLADPIPALPPVPRKANFIQLDGVSQPAAAEIVRSFVRVSCTMPLKLDGYPQAKKTGFGLVIDAEKGLVVVSRAIVPYDLCDINVTVADSIIVSAKVVFLHPLQNYTIVQYDPSLVQAPVQSARLSTEYIKQGQSTIFVGFNQNFRIVVAKTAVTDITTVSIPANASAPRYRAINLDAITVDTGLSGQCSNGVLVGEDGVVQALWLNYLGERTPSSHKDVEYHLGFATPALLPVASKVQAGEMPKLRILNMESYVVQMSQARIMGVSEEWIQRVTQANPSRHQLFMVRKVDCPPAGFSTTAHDSFQEGDIILTLDGQLITRVSELDIMYDKDVLEALIVRNGQEMKIQVPTVPTEDLETDRAVVFCGAVLQKPHHAVRQQISKLHSEVYVSARSRGSPAYQYGLSPTNFITAVNGVPTPNLDTFVQEVSKIPDNTYFRLRAVTFDNVPWVVTMKKNDHYFPMSEYIKDPAHPAGWKTVSHDKAKHKDGIAPDAANLNPDAMDEGFDDVSELEPEVRLEVGHWTVR
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease nma111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_STAAE
Sequence: MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_HAES1
Sequence: MLFAIGQRWISESENSLGLGIITGQDNRTVTISFPASDETRIYALASAPLTRVLFQKGDEITHQLGWKARVVDVMMRNELAFYLVQRLDNNEEIVVQEMELAHQISFSKPQDRLFSTQIDRNEHFVLRYKALKHQQEQFQSSLRGLRGNRAGLIPHQLHIAQEVGRRIAPRVLLADEVGLGKTIEAGMILQQQLLAEKVQRVLILVPETLQHQWLVEMLRRFNLHFSLFDEERCADFDNPEDHVEANPFVAENLIICALDWLVQQPKRAKQALAGEFDLLIVDEAHHLTWSEDSPSIAYELVMQLSAVIPAVLLLTATPEQLGQQSHFARLHLLDPNRFYSYRAFEKEQQQYQPVAKAVQSLLSEHILTVEEQNHLAELLSEQDIEPMLKVINSQADTEQKQVARGELMSNLIDRHGTGRLLFRNTRQGVQGFPHRIYHQIKLDLPTQYQNAINVLNMLGEIKDPELFYPEQIFQKMNADATWWRFDPRVDWLINLVKSLREEKILVICQDAITAIQLEQALREKEGIRSAVFHENMSIIERDRASAYFAQQEEGAQVLLSSSIGSEGRNFQFACHLVLFHLPNNPDLLEQCIGRLDRIGQRRDIQIYVPCFADTPQIRLAQWYHEGLNAFEETCPMGAILHEKCGAKLTEFLTSDTTDDFQAFIQQTHQQQLQLKSELEQGRDRLLELNSNGGEQAQQLANDIAIQDGSTELIDFTLNLFDIIGVEQEDLGEKSIVISPTGTMLVPDFPGLKEEGVTVTFDRDLALAREDLEFLTWDHPIVRNGIDLIVSGDIGKSAVALLVNKQLPTGTLLLELVYIIESQSPRGLQLTRFLPPTPLRLLLDIKGNDLSHQISFQGLQKQLKPMGKNMATKVIKIMRPAIEQLIKQSAKNVVEPAKMIIEQAKQLADQSLSAEINRLYALQAVNKNIRPEEIEQLESQRTLSLELLNQANWRLDSLRVIVSNKE
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: CODY_STAAR
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISOH_RHOSX
Sequence: MSTVLVVGADKGIAHSISRQLHDRGEDVIAACLFDGADLAAAGITVEPGVDVTSQESVEALAARLSEKGVKLDAVFHVAGVMWLDEVGSLDYDLIRRQIEINTLGPLRTIEAVRPLLNEGAKVGIVTSRVGSLGDNTSGGMYSYRISKAAANMVGLNFHHDLSKDGVSVLLLHPGMVATDLTKDFPGEHSYITPEQAAAGLIKNIDNLTPETSGRFQHSDGTFLQW
What is the function of this protein?
Involved in isoprene degradation (PubMed:10094686, PubMed:10715003).  Catalyzes the two-step NAD(+)-dependent oxidation of 2-glutathionyl-2-methylbut-3-en-1-ol (HGMB) to 2-glutathionyl-2-methylbut-3-enoate (GMBA) (PubMed:10094686).
What are the official names of this protein?
1-hydroxy-2-glutathionyl-2-methyl-3-butene dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYFA_STRA3
Sequence: MDLQKQLEELKISTQEKLKEMTGNHTKELQDLRVQVLGKKGSLTELLKGLKDLSNDLRPVVGKQVNEVRDILTKAFEEQAKVVEAAKIQAQLESESVDVTLPGRQMTLGHRHVLTQTSEEIEDIFLGMGFQVVGGFEVEKDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTMDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQIEGLVVGENISMGDLKGTLQLISQKMFGAERKIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKQTGWIEILGAGMVHPSVLEMSGIDSEKYSGFAFGLGQERIAMLRYGINDIRGFYQGDVRFTDQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL331_BACCN
Sequence: MRVNITLACTECGDRNYISKKNKRNNAERLELKKYCKRDKKSTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y1400_CLOK5
Sequence: MEERIRLSILLDIYGELLTEKQRNVLDLYYNQDLSLAEIAEHTSTSRQAVYDIIKRCHMLLVHYEDKLNLMEEKKNIEENKKGIIDFIDSLYSDKNAEVLDKIKNYIMNNI
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein CKL_1400.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: ZFN2B_HUMAN
Sequence: MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAQHHCGSAYQKDIQVPVCPLCNVPVPVARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERAGCRQREMMKLTCERCSRNFCIKHRHPLDHDCSGEGHPTSRAGLAAISRAQAVASTSTVPSPSQTMPSCTSPSRATTRSPSWTAPPVIALQNGLSEDEALQRALEMSLAETKPQVPSCQEEEDLALAQALSASEAEYQRQQAQSRSSKPSNCSLC
What is the function of this protein?
Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum.  It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum.  It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed.  May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation (By similarity).  By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333).
What are the official names of this protein?
AN1-type zinc finger protein 2B, Arsenite-inducible RNA-associated protein-like protein, AIRAP-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor.
Protein: Y1088_BACP2
Sequence: MQNRIEIAEATLKEDRLILTTKSEEQIQKAKASGQMLVDSDHFAFVYILENEESFSYLILGEDTWAPLKEAMTLDIPVYLAAEGHSLELIQLHQELHYLIDNIKDNANYGDMEEKVKSTFL
What are the official names of this protein?
UPF0738 protein BPUM_1088.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.