PharMolix/UniProtQA huggingface dataset:
Protein: AMO2_ARATH
Sequence: MSQLLLFTILVFSSVFVIGSLSFIPPPHPFDPLTEIELNLVRNIINERYPIGLEHRFTFQYVGLNEPDKSLVLSWVSSQYHNVKSPPRQAFVIARDHGKTREIVVDFASQAIVSEKIHVGNGYPMLTIDEQQATSELVLKFKPFRDSIRRRGLNVSEVVVTTSTMGWFGEAKPERLIKKRPFYLNGSVNTYLRPIEGMTIIVNLDQMKVTKFRDRFTSPLPNAKGTEFRISKLKPPFGPSLQNAVLFQSEGPGFKIDGHTNRWANWEFHMSFDVRAGLVISLASIFDMDVNKYRQVLYKGHLSEIFVPYMDPSEDWYFRTFFDCGEFGCGQYAVSLEPYTDCPGNAAFMDGVFASQDGTPIKITNVMCIFEKYAGDIMWRHTEIEIPGLKVRPDVSLVVRMVTTVGNYDYIVDYEFKPSGSIKIGVGLTGVLEVKPVKYVNTSEIKEDDIHGTIVADNTIGVNHDHFVTYRLDLDIDGTDNSFVRSELVTKRTPKSVNTPRKSYWTTKRLKAEELLVVNPSRKTKHGNEVGYRLLHGPASEGPLLAQDDYPQIRAAFTNYNVWITPYNNTEVWASGLYADRSQGDDTLAVWSQRNRKIEKTDIVMWYTVGFHHVPCQEDFPTMPTLFGGFELRPTNFFEQNPDLKTKPIKLNTTPTCTARND
What are the official names of this protein?
Primary amine oxidase 2, Amine oxidase [copper-containing] 2.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
Protein: RIBBA_BACFN
Sequence: MEPIRLNTIEEAIADFKEGNFVIVVDDEDRENEGDFIIAAEKITPEKVNFMLTHGRGVLCAPITEERCAELELDMQVSSNTSIYETPFTVTVDLLEGCTTGVSMHDRAMTIRALADPKTKPADLGRPGHINPLRARSRGVLRRAGHTEASVDLAKLAGLYPAAALIEIINEDGTMARLPQLVEVARRFGLKIISIKDLIAYRLQMESIVDRGVEVDMPTQFGHFRLIPFRQKSNGMEHIALIKGTWDTDEPILVRVHSSCMTGDIFGSCRCECGEQLHKAMEMIEAAGKGVIVYMNQEGRGIGLMNKIAAYKLQEEGYDTVDANLHLGFDADERDYGVGAQILREIGVKKMKLMTNNPVKRIGLEAYGLEITENVGIEIKPNPYNERYLKTKKDRMGHTLHFNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: RL7_SHIB3
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VP30_EBOZ5
Sequence: MEASYERGRPRAARQHSRDGHDHHVRARSSSRENYRGEYRQSRSASQVRVPTVFHKKRVEPLTVPPAPKDICPTLKKGFLCDSSFCKKDHQLESLTDRELLLLIARKTCGSVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIRTIEDSKLRALLTLCAVMTRKFSKSQLSLLCETHLRREGLGQDQAEPVLEVYQRLHSDKGGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDNEEASTNPGTCSWSDEGTP
What is the function of this protein?
Multifunctional protein that acts as a viral transcriptional activator.  Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription.  Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA.  Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures.  Assists also stop-start transcription at gene junctions to promote transcription of downstream genes.  Interaction with NP plays a critical role in transcription initiation by recognizing the RNA stem loop (By similarity).  Interaction with host RBBP6 interferes with NP-VP30 interaction and inhibits viral RNA synthesis (PubMed:30550789).  Also acts as a suppressor of RNA silencing by interacting with host DICER1 and TARBP2/TRBP (PubMed:21228243).
What are the official names of this protein?
Transcriptional activator VP30, EbolaVP30, eVP30, Minor nucleoprotein VP30.
What is the protein family that this protein belongs to?
Belongs to the filoviridae transcriptional activator VP30 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Present in viral inclusion bodies due to its interaction with NP.
Protein: QOR_LEIAM
Sequence: MSSPSNFKKLQVVSLSKDFRSSTSVVEAHLPEEVPEGMVRVSVKYAGVNASDLNFTNGSYFKNVQPPFDCGFEAAGTVVQIGAGVANVKVGDHVVLMQYGCFAEFLDAPAERCIPVPELKPEYSVLPVSALTAAVALGEVGRVKKGDVALVTAAAGGTGQIAVQLLKHVYGCTVIGTCSSEEKAEFLKSIGCDHVINYKTESLDGRLHELCPKGVDVVYECVGGHTFNDAVRHVAVHARVVIIGSISSYKSGEVVPFSDPSGTSVTMLLLVKSASLNGFFLPQFHDVIPKYMANLLQYLKAGQVKLFVDKKVFHGLSSVADAVDHLYSGANYGKVLVEIQ
What are the official names of this protein?
Probable quinone oxidoreductase, NADPH:quinone reductase, P36.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: FABH_NEIM0
Sequence: MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALDAAGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_GLAP5
Sequence: MSNPKRKILVTCALPYANGAIHLGHMLEHIQADIWVRFQRMRGNEIHFVCADDAHGTPIMLNADKLGITPEQLIEKAKADHIADFAGFNISFDNYHSTHSEENREYTSAIYKKLKANGFIKSKVISQLFDPEKNMFLPDRFVKGTCPKCKAEDQYGDNCEVCASTYSPMDLINPRSVVSGSTPVVKQSEHFFFDLPSFEEMLKAWTRSGSLQPEIANKVQEWFESGLQQWDISRDAPYFGFEIPDSENKFFYVWLDAPIGYMASFKNLCDRTGLNFDDFWKKESDAELYHFIGKDIVYFHSLFWPAMLEGSEYRKPTNVFAHGYVTVDGQKMSKSRGTFIQASTYLKHIDPECLRYYYAAKLNDRIEDLDFNLEDFVQRVNSDIVNKLVNLASRTAGFITKRFEGKLASTLENQALFDEFVAQSEQIATYFETREYNKAIREIMALTDKANKYIDDKAPWVIAKEEGTDAELQAVCSMGLELFRVLMSYLKPVLPKLAERAEAFLQTELRWDNIGSPLFAHSIAPFKSLFSRLEKKQIDAVIEETKALFAESVKAETAKKGKEMTACETKVEPIAPEITIDDFAKLDLRVAKVLKCEAVPKSDKLLRFELDLGDHTRQVFSGIKAAYSQPEELEGRFVIMIANLAPRKMSFGMSEGMILSAGTGGADLYLLSADSGVTAGMQVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4184_PHOPR
Sequence: MLCVTTSDIIGREITETLGVVTGNVVQSKHVGRDIMAGFKTIFGGEIRGYTEMLTEAREEALNRAIADAQSQGADAIVNLRFTTSAIMQGASEILAYGTAVKL
What are the official names of this protein?
UPF0145 protein PBPRB0184.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: DNAK2_PROMA
Sequence: MGKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYTKNQDQLVGQIAKRQAVMNPENTFYSAKRFVGRRVDEVNEESKEVSYSVEKSGSSVKLKCPVLDKQFSPEEVAAQVLRKLSEDAGKYLGENINQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDRKSNERILVFDLGGGTFDVSVLEVGDGVFEVLSTSGDTHLGGDDFDKVIVDHLAATFKANEGIDLRQDKQALQRLTEAAEKAKIELSNATQSEINLPFITATPEGPKHVDLTLTRAKFEELASNLIDRCRVPVEQALKDAKLSTGEIDEIVMVGGSTRMPAVKELVKRVTGKDPNQTVNPDEVVAVGAAIQGGVLAGEVKDILLLDVTPLSLGVETLGGVMTKMITRNTTVPTKKTETYSTAVDGQTNVEIHVLQGEREMASDNKSLGTFRLDGIPPSPRGVPQIEVTFDIDANGILSVTAKDKGSGKEQSISITGASTLSDNEVEKMVKDAETNATADKEKRDRIDIKNQAETLVYQTEKQLGELGDKVDEEAKAKVEAKRIQLKEATEKDDYETMKTLVEDLQKELYSLGASVYQQSNAASQAADGTSSESNNSTEGNDDVIDAEFTESK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK2, HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TYSY_STAES
Sequence: MYNPFDEAYHGLCEEILEIGNRRDDRTHTGTISKFGHQLRFDLTKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYVQSDDYHGPDMTDFGHRSQQDPEFNEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BACFR
Sequence: MEHQLTIYNTLDRKKELFVPLHAPHVGMYVCGPTVYGDAHLGHARPAITFDVLFRYLTRLGYKVRYVRNITDVGHLEHDADEGEDKIAKKARLEQLEPMEVVQYYLNRYHKAMEALNVLPPSIEPHASGHIIEQIELVKKILDAGYAYESQGSVYFDVAKYNKDHHYGKLSGRNLDDVLNTTRELDGQEEKHNPADFALWKRAQPEHIMRWPSPWGDGFPGWHAECTAMGRKYLGEHFDIHGGGMDLIFPHHECEIAQSVASQGDDMVHYWMHNNMITINGTKMGKSLGNFITLDEFFSGSHKLLTQAYSPMTIRFFILQAHYRSPVDFSNEALQAAEKGLSRLMEAVDSLEKITPAATSNVDVKSLRTKCFEAMNDDLNTPIVISHLFDGAKMINNIIAGNNTISADDLKDLKEVFHTFCFDILGLKEEIGSSDGREAAYGKVVDMLLEQRVKAKANKDWATSDLIRNELTALGFEIKDTKDGFEWKLNK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CLOBK
Sequence: MQSERQKYIRNFSIVAHIDHGKSTLADRLIEATGTLTEREMDTQVLDNMDLEKERGITIKSQAVRLIYKRNTGEEYTLNLIDTPGHVDFNYEVSRSLAACEGAILVVDATQGIQAQTLANCYLALDNDLEIVPVINKIDLPSARPEEVKQEIEDVIGIEAEDAPLVSAKTGLNIKDALEAIVNKVPAPEGDEKAPLKALIFDSYYDSYKGVVCHIRVKEGTIKEGTEIKLMNTGKVYEVVEVGVFVPNYMPVDELKAGDVGYVTASIKNVRDARVGDTITEAKRSANEALSGYRPAVPMVFSGIYPVDGAKYEELKEALEKLQVNDAALSFEPETSIALGFGFRCGFLGLLHMDIIQERLEREFNLDIITTAPSVIYKITKTDGTLIELTNPTNMPSPSEIKLMEEPIVKSSIITPSDYVGAVMDLAQNRRGIFKDMQYLDTTRVSLNYEIPLNEIIYDFFDALKSRTRGYASFDYELIGYKDADLVKLDILLNADVVDALSMIVPRERAYAKGRNMAQKLKEIIPRQMFEIPIQAAVGAKIIARETIKAMRKDVLAKCYGGDISRKRKLLEKQKEGKKRMRQVGSVEVPQEAFMAVLKTEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PO3F4_MOUSE
Sequence: MATAASNPYSILSSSSLVHADSAGMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTSLSDGGPWSSTLATSPLDQQDVKPGREDLQLGAIIHHRSPHVAHHSPHTNHPNAWGASPAPNSSITSSGQPLNVYSQPGFTVSGMLEHGGLTPPPAAASTQSLHPVLREPPDHGELGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHEVYSHTVKTDASCHDL
What is the function of this protein?
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
What are the official names of this protein?
POU domain, class 3, transcription factor 4, Brain-specific homeobox/POU domain protein 4, Brain-4, Brn-4, Octamer-binding protein 9, Oct-9, Octamer-binding transcription factor 9, OTF-9.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPNP_SULDN
Sequence: MTKFENVTVVKKANIYDGGKVTSRTVEFADGTRKTLGIMMPGEYTFNTAEAEIMEMMSGELDIRLPNEDWKTLNTPESFNVPANSSFDLKIRTVTDYCCSYIK
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TPIS_DICT6
Sequence: MRRKIIAANWKMYKTCAETESFIKEFIELSKGYEEKEIVICPPFTSLYVASKLLKDTAIKLGAQNMFWEKEGAYTGEISPIMLKDLNCTYVIIGHSERRNYFSETNEMINKKIKSAFNYGLIPIFCVGEKWEERERGKTEEVITKQVREGLEGLEKENVEKIVIAYEPVWAIGTGHSAKGEDANEVAGLIRKIISEMYDTEVSQKIRIQYGGSVNPQNITEFLSQNEIDGALVGGASLKPQSFWNIVKS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA2_SYNY3
Sequence: MTSDDAAAGLVRVLDAAQGAFLALDSYGGNDRSRAVLAMAEALERSFAQILEANTLDLVVSREMSVADCLCEWLKLTPERLQNTVTILKRLASLPDPLQRVMASPYQFNLAQTYCQLMPLGVVALVYESFPELAAIAAGFCLKTGNSLVLRSCGASSHSTAAICEILREGLLDADLPVDSVSHIPSETSPNVQDLVGNASQLNLVIPYGRPSFVEQISQQCTPPVLKAAMGNCYLYWSSKGDLEMVRQMIIDSHVGHPDPVNAIEKVLVSPGQNPAPLVRLLNNLQAKGFKLRGDAELCEQFPDHLTLAKENEWGKAYLDRTVAFRTTQNLKTAIAWINSHSSGHGDCIATDSYQESRQFSMGVDSALVYVNIPPYFCRNPRHGESLFLGVSSQKGQRRGLIGLEAFMTPKQIVQGESRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase 2, GPR 2, Glutamate-5-semialdehyde dehydrogenase 2, Glutamyl-gamma-semialdehyde dehydrogenase 2, GSA dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV20
Sequence: MIGKEVTLQDIVLELNELQPEVQPVDLFCEEELPNEQQEREEEPQIERASYKVVAPCGCCKVKLRIFISATEFAIRSFQQLLIDELQLLCPDCRGNCKHGGS
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: TRUA_BACFR
Sequence: MSVQRYFIYLAYDGTHYHGWQIQPNGISIQECLMKALATFLRKDTEVIGAGRTDAGVHASLMVAHFDYEGEPLDVDKVAEKLNRLLPQDISVYKVCRVKPDAHARFDATARTYKYYITTVKFPFNRQYRYRIHNPLDFQKMNEAALTLFHYSDFTSFSKLHTDVKTNICKIMHAEWTQEDEYTWVFTIQADRFLRNMVRAIVGTLLEVGRGKLSVVDFRKIIEQQNRCKAGTSAPGNALFLVNVEYPQEIFE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NHAA_RENSM
Sequence: MITSRTARRTFRRNSYPEHLRITAILRKETVGGALLLAATIAALIWANSPGSESYFALRDAKIGFNPFGLKLDLSLGAWASDGLLAIFFFIAGLELKREFIAGDLRRFDRAIVPIAAAIGGVAVPAIIYTLINLSSGAEILNGWAIPTATDIAFALAVLAVISTHLPTALRTFLLTLAVVDDLIAISIIAVFYPHNLQPQYLALALIPLGLFTWAVQKRIRSWYLLLPLAIITWVLVHESGVHATVAGVLLAFAVPVVRRDRNPDNGPGLAEHFEHRFRPLSAGVAVPIFAFFSAGVAIGGWAGFTNSLTDTVAIGIIAALILGKAIGIFGATFLITKTTRASLDDGLSWIDVLGLAILAGIGFTVSLLISELAFGADSPHNDHAKVAILTASLVAALLATVILRIRNQHYRKLEKLESVDADGDGVPDVFDEKDD
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_LEPBL
Sequence: MIQIKRALISVSDKSDIVEFAQFLNQNGVEIISTGGTLKLLKDNGIQAIAIDDYTGFPEILEGRVKTLHPKVHGGLLGVVSNPAHKQKMEELKIPKIDLVVVNLYPFLKTVSKPGVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPSDYEEVRVLIASGGISEEVAAGYMRKAFSHTAMYDTAISSWFHKQAGDVFPDVLNLSFLKKQKLRYGENPHQAASFYEPLFVKSDFSPLQGKELSFNNMLDFDAAFHISSLLPENTVCIIKHLNPCGIAYADDPLEAFQLARRTDPISAFGGVIGIKGIVHGELATAITENFVEGVIAQKFTPEALELFSKKPNIRLIEIENFKEALDELDLRPIHHGLLIQERDYTTITEKDLKVVTKKQPTSDDIRGLMFAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSVVGSYVASDAFFPFRDGIDALAKAGAKAIIQPGGSVRDAEVIQAADEHGLIMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SYA_LISW6
Sequence: MKQLSSAEVRQLFLDFFKEKGHTIEPSAPLVPNNDPTILWINSGVATMKKYFDGSVIPDNPRMANAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEGAIVFAWEFLTSPKWIGFDPDKLYVTVYPEDEEAKTIWREKIGLSEEHIVEIEDNFWDIGIGPSGPDSEIFYDRGPTFGDDTSDPELYPGGENERYLEIWNLVFSQFNHNPDGTYTPLPKQNIDTGMGLERMVSIIQDAPTNFETDLFMPIIREVEQIAGVKYGHNQENDVAFKVIADHIRTVAFAIGDGALPSNEGRGYILRRLLRRAVRYAKVLTINEPFMYKLVPVVGKIMNSFYPEVENQTDFIQKVIRTEEERFHETLNEGLAILETILKTAKETNEQVIKGADIFKLYDTFGFPVELTEEYAEDHGLKVDHAGFEAEMKEQRDRARSARADVKSMQVQGELLANLTAKSEFVGYNATEHVSEILYIIQDDALVDEVASGKTAQVIFKETPFYAESGGQVADKGTIESETGLAYVEDVQKAPNKQNLHRISVKEGVLKTGDTVKLAVDKVKRRETIKNHTATHLLHRALKDTLGEHVNQAGSLVSPDRLRFDFSHFGQITEEELTKMEEIVNEKIWEQINVVIEEMPIAEAKELGAMALFGEKYGDVVRVVQVGKYSIELCGGVHVRNTADIGLFKIVSETGIGAGTRRIEAVTGKEAYRFVTEQENTLKHTANLLKATTKEAPQKVEQLQADLREVKRENESLLSKLASAASADIFESPEEIGGVKVIAKQVNAKDMNQLRQFVDNWKDKKIGGILVLGAVQGEKVNLISAVSEDAIKAGYHAGKLLKEVATKCGGNGGGRPDMAQAGGKNPAELATALDYVSTCVKEQQA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_POLAQ
Sequence: MAKNKFNKSWLQDHLTDPYVKMAQKEGYRARAVYKLSEIDEQDHLIKAGMTIVDLGSAPGSWSQYVRNRLTELGKSNPKIESGKPDGQIIAIDILPMEDIADVSFIQGDFREEEGLAALEALLPKSAEGKVDLVLSDMAPNLSGVGVADSARMAFLAEIALDFATAHLKPEGALLIKCFNGSGYSQIVESFKKVFKTVASRKPKASRAKSSEIFLLGKNLKPPK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_ANADF
Sequence: MLQPARTKYRKMMKGRMRGKAYRGSDLNQGEYGLQATECGWLTARQIEAARVAITRYVKRGGKLWIRVFPDKPITKKPAETRMGTGKGNVEYYVAVVKPGRVLYELAGVDDESAKKAFHLAAHKLPVATKLVKRGSTL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: VSI10_MOUSE
Sequence: MAGLRVLLCLGALLARQGSAGLQLLLNPSRANLSVRPNSEVLPGIHPDLEAVAIGEVHDNVTLRCGSASGSRGLVTWYRNDSEPAFLVSFNSSLPPAAPRFSLEDAGALRIEALRLEDDGNYTCQEVLNETHWFPVRLRVASGPAYVEVNISATGTLPNGTLYAARGSQVDFNCCSAAQPPPEVEWWIQTHSIPEFLGKNLSANSFTLMLMSQNLQGNYTCSATNVLSGRQRKVTTELLVYWPPPSAPQCSVEVSSESTTLELACNWDGGYPDPTFLWTEEPGGTIMGNSKLQTLSPAQLLEGKKFKCVGNHILGPESGASCVVKLSSPLLPSQPMRTCFVGGNVTLTCEVSGANPPARIQWLRNLTQPAIQPSSHYIITQQGQSSSLTIHNCSQDLDEGFYYCQAENLVGVRATNIWLSVKEPLNIGGIVGTVVSLLLLGLAVVSGLTLYYSPAFWWKGGSTFRGQDMGDVMVLVDSEEEEEEEEEEEEKEDVAEEVEQETNETEELPKGISKHGHIHRVTALVNGNLDRMGNGFQEFQDDSDGQQSGIVQEDGKPV
What are the official names of this protein?
V-set and immunoglobulin domain-containing protein 10.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ZP3_MACRA
Sequence: MELSYRLFICLLLWGSTELCYPQPFWLLQGGASRAETSVQPVLVECREATLLVTVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGSSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKAIPAEQEPDELNKACSFSKSSNSWFPVEGPADICQCCSKGDCGTPSHSRRQPHVVSQWSRSASRNRRHVTEEADITVGPLIFLDRSADYEVEQWALPADTSVLLLGIGLAVVASLTLTAVILIFTRRWRTASRPVSASE
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP3 is essential for sperm binding and zona matrix formation.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3, Sperm receptor, Zona pellucida glycoprotein 3, Zp-3, Zona pellucida protein C.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPC subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 3]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: RL3_DESVH
Sequence: MAEKMGILGRKIGVTRIFASDGSAVAVTVIKAGPCPVTQVKTVATDGYDAIQIAFDEAKEKHLNKPEIGHLAKAGKGLFRTLREIRLEAPAAYEVGSELDVTLFATGDRVKVSGTSIGKGYQGVMRRWNFAGSKDTHGCEKVHRSGGSIGNNTFPGHVFKGKKMAGHWGNESVTVLNLEVVDVRPEDNVILVKGSVPGPKNGLVMVRKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.