PharMolix/UniProtQA huggingface dataset:
Protein: OCLN_XENLA
Sequence: MYSRPSNYAPSKDVYGGEMRSQPAYSYYPEEEIQHFYRWSSPPGIIKIMSILIVVMCVGIFACVASTLPWDLDITGQSMGYGMGSGSYSGGYTGYGFGGSQMGLGFAYGGNYTDPRAAKGFILAMAAFCFIIGLVIFVMLVTRTPLSTSRKFYLIVIIVSAIIGGLVFIATIVYTVGVNPVAQASGSAFYTQIVSICNQFYSPVQTGVFVNQYLYHYCVVEPQEAIAIVLGFLIVVAFAIIIFFAVKTRKKINQYGKTNILWKKNHIYEDGDPQVEQWVKNVAENSAPALSDYNEKVDGSVADYRSANGVQAYPSQNNISHPIAEEELPLKEDYGMSPRHYSSSSDATTKKAPPKKRPGKPRRSDLDTNEGGYNTGGESADELEDDSWDSEYPPITQTKQRQEYKQEFASDLHEYKRLQAELDELSKIPVPSLNRELGQSSRKDSEEYRTVADKYNRLKEIKSSADYRNKKKRCKGLKTKLNHIKQMVSNYDK
What is the function of this protein?
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
What are the official names of this protein?
Occludin.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, tight junction.
Protein: RS3_PROMT
Sequence: MGHKIHPTGIRLGITQEHRSKWYAPSKTYPLLLQEDDRIRTFIKKKYLAAGISDVLIARKADQLEVELKTARPGVIVGRQGSGIEELRSGIQKTIGDRNRQVRINVVEVEKVDADAYLLAEYIAQQLEKRVAFRRTIRMAVQRAQRAGVLGLKIQVGGRLNGAEIARSEWTREGRVPLHTLRAEIDYATKVASTTYGVLGIKVWVFKGEVLPKEEQPLPVGSSPRRSRGNRRPQQFEDRSNEGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CAP16_ARATH
Sequence: MGRITSFADLIGRIKDKASQSKAALVSSNTKSKTLSFHLSVLRATTHDPSTPPGNRHLAVILSAGTGSRATASSAVESIMERLHTTGDACVALKSLIIIHHIVKHGRFILQDQLSVFPASGGRNYLKLSAFRDEKSPLMWELSSWVRWYALYLEHLLSTSRIMGFFISSTSSTIHKEEYEEMVSSLTNSDLLREIDALVGLLEEACKIPDLPFSGGKSLADKITQLVGEDYVSSINELYTRFNEFKERSNTLSFGDTIELVCALKRLESCKERLSEICHGNWKRGWIDGFWGLVLEVKGIIGNLEDNYGQIEKSIVGFGKRDKGYESARFTDRLIIGYSNPVRFSSGRFSNVDRFNFPVSGRVLC
What are the official names of this protein?
Putative clathrin assembly protein At4g40080.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: ATP8_APILI
Sequence: MPQMMPMKWFLIYFIYLLIFYLFIMLINSMLIKTKINKETLKIKLKKWNWFW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: EFTU_OLEA2
Sequence: MGKEKFERTKPHVNIGTIGHIDHGKTTLTAAITKIASLKMGSKAVAYDEIDKAPEEKERGITIATAHVEYETTLRHYAHVDCPGHADYIKNMITGAAQMDGAIIVVAATDGPMPQTREHILLARQVGVPSIVVFLNKCDMVDDEELLELVELEVRELLSSYDFPGDDTPVIRGSALKALECDSADDDAAKPILELLDACDSYIPEPERDTDKPFLMPIEDVFSISGRGTVVTGRVERGIIKVGEQIEIVGIKDTMTTTCTGVEMFRKLLDQGQAGDNVGVLLRGVKRDDVERGQVLAAPKSITPHKKFKAEVYVLSKEEGGRHTPFFSGYRPQFYFRTTDITGIIGLEEGVEMVMPGDNATFIVELIHPVAMEQGLRFAIREGGRTVGAGVVSEILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_RHOPA
Sequence: MPALILPLIEAAVHWPVRGALLGLDLGTKTIGVAASDPDRKLATGVETIARKAFTADAARLLALAAERTACGFVLGLPLNMDGSEGPRAQSTRAFARNLSRLTELPIGLWDERLSTAAVERELIANDVSRAKRAKVIDEHAAIFILQGALDRLAALRRAE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_STRPD
Sequence: MSTSIKAIKESLEAVTSLLDPLFQELATDARLGVQKALKSRQKAIQADLAEEERLEAMLSYEKALYKEGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIKGLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLEGQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFPGYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCNSTNP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_MESH2
Sequence: MDNKKIRNFAIIAHIDHGKSTLADRILEFTNTVSKRDLKEQHLDSMDLEKERGITIKLNAVQIRYNSYIFHLIDTPGHVDFTYEVSRSLAATEGALLLVDASQGIQAQTLANVYLALENNLEIIPIINKIDLPSANVDKVKAEIENTIGISAENAILISAKNGIGIEKVLEAIVNLIPPPQASDEKDPLKALVFDSYFDIYRGVIIFIRVVTGKISVGDTFKFMANNLKFSVIELGISSPNQVKKEALFAGEVGWVAASIRNAKDVEVGDTITLVENPAKSPLPGYKKLVPVMYTGFYPVDSQQYNLLKDSLEKISLSDSSIIYEPESSKALGFGFRIGFLGLLHMEILQERLEREFNLSIIATAPSVEFQITRTNGQVQIISNPSLFPEPNFISEIREPYILAKIFLPEEFLGQIMGLCQDKRGIYVDLEYIDDFRRRLIYKLPLVEVIFDFFDRLKSLSKGYASFEYEVIDYQVSKLQKLDILLNGQKIDALSMIVHKDFAYPKARDLTQKLKEIIPRHSFEVPVQAVIGSKVIARETIKAYRKDVTAKLYGGDVTRRKKLLEKQKAGKKRMKSFGVVDVPQEAFLAILKTNINEK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUOD_ALBFT
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETKTYIQALPYMDRLDYMSMMCNESAYCLAVEKMLGLEVPIRAKYIRVMFAEITRLLNHLLCVGAGALDCGAMTVMLYAFREREDLLDMYEAVSGARMHAAYFRPGGVYRDLPDTMARHQPNKIRSAKSTEKLNRNRDGSLLDFIDDFTQRFPTYLGEYHTLLTDNRIWKQRTVGIGVVTAERALNLGFSGPMLRGSGVAWDLRKKQPYEIYDRLDFDIPVGKTGDCYDRYLVRMEEMKQSNRIIKQCVDWLRVNPGPVITDNHKIAPPNRESMKSNMEELIHHFKLFSEGFSVPEGEAYATIEHPKGEFGIYMVSDGANKPYRMKIRPPAFVHLAALGEMGRGHMIGDAVAIIGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL17_THESQ
Sequence: MRHRVKRHRLGRYGSHRKSLLRNLSREIVEHGSIVTTTAKAKALKILMDKLVSKAIEAATTDDKAKSVHLRRQINAVLGDRRLTNKLVDEIAKNYVGRHGGYVRVLRIGFRRGDAAEMSLVQLVEASSQEG
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GAP2_PSEAB
Sequence: MIPLIGQLYRNNNVVTSIHGRGLINRSVIAIMKAHRFARHRMADDAELSVHETFPILKAMSELKLGAASVDLGKMVAKFKAEGNGRSIEDFVKAELAEVAGKQNGDAREGTDVVLYGFGRIGRLLARILIEKTGGGDGLRLRAIVVRKGAENDLVKRASLLRRDSVHGPFDGTITIDEENNTLTANGNLIQVIYSNDPASIDYTQYGIKNALLVDNTGKWRDAEGLGQHLKCPGIDRVVLTAPGKGALKNIVHGINHTDIGADDKIISAASCTTNAIVPVLKAVNDQYGIVNGHVETVHSYTNDQNLIDNFHKGSRRGRSAPLNMVITKTGAATAAAKALPVLKGKLTGNAIRVPTPNVSMAILNLNLEKATTREEINEYLRQMAMHSDLQKQIDFVSSQEVVSTDFVGSRHAGVVDAEATICNDNRVVLYVWYDNEFGYSCQVVRVMEDMAGVNPPAFPR
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase-like protein.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Protein: RRP32_ARATH
Sequence: MAVQANQSASFGFRTASPSQKLSSKPIAHISLSTKLKPSSRPSLSCSTWNQGQIPARHSCINPGIFAYPPSNLTFSHELPESESPPLGKKKMRVLVKPLEKPKVVLKFVWMQKDIGVALDHMIPGFGTIPLSPYYFWPRKDAWEELKTLLESKPWISELHRVFLLNQATDIINLWQSSGGDLS
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
30S ribosomal protein 3-2, chloroplastic, Plastid-specific 30S ribosomal protein 3-2, PSRP-3 2.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YCB2_YEAST
Sequence: MKSLFYLKLLLWVVLLSLCLLMAHRKTKVADKFRALRSRIQLRFNRHIRLNDSFADDLENGLHSRNFDIISENSNDVRGGLDDVSKNEIKQIMENDNVDFDKARLLYMERKFGQNGIAPDGTPIDPKAFTFDSR
What are the official names of this protein?
UPF0357 protein YCL012C.
What is the protein family that this protein belongs to?
Belongs to the UPF0357 family.
Protein: MUTS_SALHS
Sequence: MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLDRLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWTLNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: UPPP_CUPPJ
Sequence: MEIALALKAVILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRRRIANVLSGLTTDPKAQRFAINVIVATVPAIVLALVFGKWIKAHLFNPITVALAFIIGGVVILLAERRDARRGMVTNPRGNALLQAAKAGAPRIESVDDLNWRDALKVGLAQCFALVPGTSRSGATIIGGMLFGLSRQVATEFSFFLAIPVIFGATVYELYKARALLSVDDLGIFGIGFVFAFLSAFLCVRWLLRFVATHDFKPFAWYRIAFGIIVLATAYSGLIAWHA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFB_HAEDU
Sequence: MKFNESWLREWVDPKVSTAQLCDQITMLGLEVDSVEPISGEFSGVVVAEVVECTQHPDADKLRVTKVNVGAERLLSIVCGAANCRQGLKVACAIEGAILPGNFKIKKTKLRGQLSEGMLCSFSELGIKEDQSSGIIELPADAPIGVDIREYLNLNDVAIEVSLTPNRADCLSIAGIAREVAVINQMEVKSPVIKPVPATLSAPIEIDIQAPSACPHYLARIIKNVNVNATSPLWLQEKLRRCGILSIDPIVDITNLSLLELGQPMHAFDAEKVKAPIQVRLAKDQEQLVLLDGTTAKLQTNTLVIADQKNVLALAGIMGGEASKVNAETKDIILEAAFFAPLALTGRTRQYGLHTDASHRFERGVDPTLARQAMERATTLIIEICGGEVAEVCEAINTEYLPKQPIIRLRRTKLDSVIGHYIEDRLVTDILVRLGLNVTCENDGWIATVPSWRFDLEIEEDLIEEIARIYGYNRIPNNALLAHLTLKGSAEKVLEPNRIKTVLVDNDYQEVVTYSFVDPKIQQLLHPQQEALILPNPISSEMSAMRVSLLTGLLQTVLYNQNRQQNRIRIFEQGLRFIPDASAESAVRQEAVFAAVIVGEKHIANWEGKSKAVDFFDLKGDLEQILALTANKELTFVAKQFPALHPGQSAAIMLNEQEVGFIGTLHPSIGQKLGIKGTPIVFELLADVVSERAIPVAKEISKFPANNRDIAIVIDEHIPAREVLSACYHAGREQLTAVNLFDVYQGANLVVGKKSLAISLTIQNTEKTLTEEEISAVIQLVLDELAQRFQASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SORC5
Sequence: MKRTYQPHNTRRARTHGFRARMATAGGRKVINNRRRKGRARLAPTIYKK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PAP1_FOWPV
Sequence: MERSRQVYYIINEYLGRHPSSTEYQVLKHQVEKISKINNFNKETFFFLLKKNKNKFFKDLELSDDLLKKRIDEYFSKQKHAKRLGNLFAIMELQKILISSFTKTIGILTTKVPEYYHSTIKLEYSSMEKIADDILDSYNVVEPSKEVKGRHKVSDLVGHVYKIMEEYLRRHSNSCLCYGSYSLHFLNNKIEYGDIDVLQTNARTFLINIAFLIKFITGRRIVLLKVPFLKNYVIMHDEETNHVMDTFNIREKTMNMIPKIMIDNMYIVDPCIQLLNMIKMLSQIDRLEELQAKFEKLSVRLGTLLEYTRYRYSIPLDSESILEVRAKLDKDKRKITVDFKKYKLNYIKCYFYLDEVELKKFISKNSGLDEYEDFEAVTNSEYAIRNKTMYTYFSNTALMRSENEIHPITINALTSHALLYHVITRKFYDDLLGDLVRSLMIVEKVPVFKIIPRDKKQGRHTIIDIEKDIIFH
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L, VP55.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: FTSH1_SORC5
Sequence: MADEKRPASRAWLGYLLIAVGILVLSGIVRSRGRPLVPYDEAVAEVRRGEISAAIVKPDEIELVRRESPQRPEERVRVTRLPGVEDEPLVRALLDKQVRIEAKSPQTSVWMQVAIWMLPLVLINAAFFMMLRRAGQGAGGPLGFLRSKAKIYDRSRQDPVRFSDVAGVDEAKDELVEVVDFLKEPSRYRSLGGRIPRGLLLIGPPGTGKTLLARAVAGEANVPFFSLNASEFVEMFVGLGAARVRELFEEARKSAPSIVFIDEIDAVGRTRGGLGALATHDEREQTLHQLLAELDGFDARTTVILMAATNRPEVLDPALLRPGRFDRQVIVDRPDLRGREAILAVHARRVPLASGVDLGLVARRTPGMVGADLAKIVNEAALAGARRGAREIGQADFDEALDRSQLGLRRRGQIMTAEERRRVAYHEAGHALVALALPAADPVERVSIVARTIGALGVTIQVPRDERQLVTEQEIESRVTVMLGGRAAEELALGQVSSGAHDDLGRATALVREMVTRLGMSRRLGLAALARTVGAPMLGVLQEERTCSEATAREVDEEVRERLGEMYLKAKQLLVDRREGLEAVAEALVLKETLRGEELEEIAAVSTRRKIAVGPPSAA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: THSA_ENTFC
Sequence: MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPATEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIETYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVITRDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPHYCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDILKSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGNSIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLESGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQALEKLDTEGEVDKKVEQIVSLINSIQED
What is the function of this protein?
NAD(+) hydrolyzing component (NADase) of the Thoeris antiviral defense system, composed of ThsA and ThsB (maybe AS248_15445).  Activated by 3' cyclic ADP-D-ribose (3'cADPR) but not its isomers 2'cADPR, cADPR and very weakly by ADPR; binds 3'cADPR better than 2'cADPR (PubMed:36048923).  Upon activation binds and hydrolyzes NAD(+), leading to cell death and inhibition of phage replication (By similarity).
What are the official names of this protein?
NAD(+) hydrolase ThsA, EfThsA, NADase ThsA.
What is the protein family that this protein belongs to?
Belongs to the soluble Thoeris ThsA family.
Protein: RS15_SHEB8
Sequence: MSLSTEAKAKILADFGRCENDTGSTEVQVALLTAQINHLQAHFKEHIHDHHSRRGLLRMVSSRRKLTAYLKRTDLARYTALIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RIMM_LACLM
Sequence: MENFYKVGTIVNTQGLQGEVRILPSTDFANERFSKGAVLALFDDKDNYIQDLKVKSGRLQKNFYVVKFEGFYHINDVEKYKGYVVKIAQENQEELNDGEFYYHEIIGSDVYDNDILIGQISEILQPGANDVWVVKRKGKRDLLLPYIPPVVLKVDVAQHRVDVDIMEGLDD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_MYCPU
Sequence: MKFQKLKGTRDYYFQDSNKLEIIRNAFFTSAKKFNFSFLETPIIENVELFKRTSGDFSDLVKKELYSFEDKSKRQIALRPEGTAPALRAIVENNLLQKHNKFFYFGPMFRYENPQKGRQRQFFSGGIEWLEKQSPFTNIEIIFFAKNFLDTLKIDDYEIVINWIGHPEQRKNYLDHLKNYLNQFENQLEEISKERLKNNALRILDDKIESQKAFVKNAPKIHDFLPKESLENFYQLQDLFKKFDIKFKVDPFLVRGLDYYSDFVFEFVSTNQNLGAQKTLLGGGVYSSLLKELGGENIEGIGFGFGLERIMEVIDLNNFKDDAKKITAFASNEDDLIALLKLRNNFGDLIKIDCINKVVNFKKIFKSKQIKESDFLIFKELNNAQNEVSLKNKFNDQKLVVDLINPNIENIKKYIKENSD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LX12E_RAT
Sequence: MGKYKILVVTGDSLLAGSTNLVQLWLVGEHAEADLGKQLRPLRGRKTELEIDVPLHLGRLLVVKLRKHKGLLDSDWFCKWITVQGPGIQGEAFFPCYSWVQGKETIYLPEGTALKVNDDTKNLFRKYREQELEDRRNVYRWGSWKEGLILPIAGSTERDLPRNQRFMEDKDLDFSLSLAKVLKDFAIKGTLDFVSRVQHLEDYQKVFPHSKTALAGRVRDSWKEDALFGYQFLNGANPMLLRRSKRLPARLVLPPGMEDLQTQLEKELKAGSLFEADFSLLDGVKPNVIIFKQQHVAAPLVMLKLQSDGRLLPMVIQLQPPRHGCPPPLLFLPSDPPMAWLLAKIWVRSSDFQVHQLQSHLLRGHLMAEVISVATMRSLPSLHPIYKLLAPHFRYTMEINTLARNNLVSEWGIFDLVVSTGSGGHVDILQRATACLTYRSFCPPDDLADRGLLDVKSSLYARDALRLWEIISRYVGRMVELFYKNDREVKEDPELQVWCREVTEIGLLGAQDRGFPLSLESRAQLCRFVTMCIFTCTGQHASTHLGQLDWYSWIPNGPCTMRKPPPTSKNVTEGDILDALPCLQQARMQITFTKFLGRHQPVMVALGQHKEEYFSDPGARAVLKQFQEELAVMDKEIEVRNASLDLPYEYLRPSMVENSVTI
What is the function of this protein?
Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy species (PubMed:23382512).  Shows increasing catalytic activity within the series arachidonic acid < 5,8,11-eicosatrienoic acid < linoleic acid < 8,11,14-eicosatrienoic acid (By similarity).
What are the official names of this protein?
Polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type, Arachidonate (12S)-lipoxygenase, epidermal-type, 12-LOX-e, e(12S)-LOX, Linoleate (13S)-lipoxygenase.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CQ098_MOUSE
Sequence: MACCYNSPRRLEKSFVLDGVAVSTMAQAYSIMRPKLWSAIPPYNPQLDHHSRRYFRSRVVPPILRKTDQDHGGTGRDGWIVDYFHIFGQGQRYLNRRNWAGAGHSLQQVSGHDYYNSNPKAITTGLNGRFGYRRNTPALRQHTSVFGEVTPFPIF
What are the official names of this protein?
Uncharacterized protein C17orf98 homolog.
Protein: TRUA_ANAPZ
Sequence: MRYKAVVEYEGTSFIGWQRQHGVVGKSVQESIERSIKEFCQQSVIVYAAGRTDAGVHATGQVVHFDLKVSREDYVIKNALNHYLRNEKVSILQLERVDEEFHARFSAKKRHYTYKISNREAPLCIDLMRMWHVPKRLNVENMREAASYIVGKHDFASFRAKDCQSKSSIKTVDSIDIIAAEEEININISAQSFLHKQVRITVGTFVECGMGLYPPAHVLEILEKKDRAAAGITAPAHGLYLTRVDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GLMM_NOSS1
Sequence: MVSSITRIQNYVIDGAATSNGLETVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPLALQIGFWAGVVLRNHADQLGPVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPCVAYLTSMSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQALQAEIEKGLRGNLPITSNVSNCGRHYSRWELVKNYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVISLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYILYLWGLYLKQQNQLPDNLIVSTVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAMLGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAELIDQSFQTYPQLLRNVRVVDRDRRLSWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNELVAQVQQHLAP
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: UPP_UREP2
Sequence: MHKIINHPLIKDKLTRMRKVSTVSTVFRTNLEELTQLMVYEATKDLELNEIEIETPVVKVAKGYKLKNKICLIPILRAGIGMVDGVKSLIPTATIGHIGLYRNEQTLKPVEYFKKFPKNISESDVIILDPMLATGGSVVEAVNIIKKYNPKSIKFVCIVAAPEGLKYVQEVHPEVDVYIAALDDKLNENGYITPGLGDAGDRIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.