PharMolix/UniProtQA huggingface dataset:
Protein: G3P_PICTO
Sequence: MIKVGINGYGTIGKRVAYAASIQDDIHVSGIVKNTPDYMAYLASRSFNIYVPDDDKIKEFEDHGIKVKGTLNDLMESSDIIVDATPEGMGMENIKIYKKKRVKAIFQGGEKSNIGDASFNAYSNYNESFKREYTRVVSCNTTALARTLYPILNDYGIENLNVTLIRRATDPNDNRKGPINAIEPSMSFPSHHADDLKTVLNLNNVYTVALKAPTTLMHVHSIEVLLKDDAKIDDIMESWLKYNRILLIEGKDNFKSTAQIMDMARELRRDRGDLYEIAIWRDSVKVIDKRLYYVQAVHQESDVIPENIDAIRSLSGIDKNESIEKTDKSLRISGGIFYGKE
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKZF1_CHICK
Sequence: METDEAQDMSQVSGKESPPISDVPDDADEPMPVPEDLSTTTGGQQSVKNERVLAGNIKIETQSDEENGRACEMNGEECAEDLRMLDASGDKMNGSHNGPGSKAMSGVGGIRLPNGKLKCDICGIICIGPNVLMVHNRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLQTMSISSNLYSVIKEETNQSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFVGEKCLSDLPYDATTNYEKENEIMQTHVIDQAINNAISYLGAESLRPLVQTPPVGSEVVPVISPMYQLHKPLGDNQTRSNHTAQDSAVENLLLLSKAKSVSSERDASPSNSCQDSTDTESNNEERSGLIYLTNHIGPHARNGISVKEESRQFDVLRAGTDNSQDAFKVISSNGEQVRVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS
What is the function of this protein?
Binds and activates the enhancer (delta-A element) of the CD3-delta gene.  Functions in the specification and the maturation of the T-lymphocyte.  Also interacts with a critical control element in the TDT (terminal deoxynucleotidyltransferase) promoter as well as with the promoters for other genes expressed during early stages of B- and T-cell development.  Function is isoform-specific and is modulated by dominant-negative inactive isoforms (By similarity).
What are the official names of this protein?
DNA-binding protein Ikaros, Ikaros family zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the Ikaros C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOD1_BOVIN
Sequence: MDGKRRPGPGPGVPPKRARGGLWDEDEAYRPSQFEEELALMEEMEAERRLQEQEEEELQSALEAADGQFSPTAIDARWLRPAPPALDPQMEPLIFQQLEIDHYVAPARPLPGAPPPSQDSVPILRAFGVTNEGVSVCCHIHGFAPYFYTPAPPGFGPEHLSELQRELSAAISRDQRGGKELTGPAVLAVELCSRESMFGYHGHGPSPFLRITLALPRLMAPARRLLEQGIRLAGLGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYILRPEGKATLCQLEADVLWSDVISHPPEGEWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWSTFIRIMDPDVITGYNIQNFDLPYLISRAQTLKVPGFPLLGRVIGLRSNIRESSFQSRQTGRRDSKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRLAVYCLKDAFLPLRLLERLMVLVNAMEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPVVKTEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLGLTEDQFIKTPTGDEFVKASVRKGLLPQILENLLSARKRAKAELAKETDPLRRQVLDGRQLALKVSANSVYGFTGAQVGRLPCLEISQSVTGFGRQMIEKTKQLVETKYTVENGYSTSAKVVYGDTDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVRRDNCPLVANLVTASLRRLLIDRDPSGAVAHAQDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAEAVLLRGDHTRCKTVLTGKVGGLLAFAKRRNCCIGCRTVLSHQGAVCKFCQPRESELYQKEVSHLSALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLRRFGPPGPEAW
What is the function of this protein?
As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair.  Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities.  Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity.  Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity.  Most notably, expresses higher proofreading activity in the context of Pol-delta3 compared with that of Pol-delta4.  Although both Pol-delta3 and Pol-delta4 process Okazaki fragments in vitro, Pol-delta3 may be better suited to fulfill this task, exhibiting near-absence of strand displacement activity compared to Pol-delta4 and stalling on encounter with the 5'-blocking oligonucleotides.  Pol-delta3 idling process may avoid the formation of a gap, while maintaining a nick that can be readily ligated.  Along with DNA polymerase kappa, DNA polymerase delta carries out approximately half of nucleotide excision repair (NER) synthesis following UV irradiation.  Under conditions of DNA replication stress, in the presence of POLD3 and POLD4, may catalyze the repair of broken replication forks through break-induced replication (BIR).  Involved in the translesion synthesis (TLS) of templates carrying O6-methylguanine, 8oxoG or abasic sites.
What are the official names of this protein?
DNA polymerase delta catalytic subunit, 3'-5' exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PCNA and POLD3 at S phase replication sites. After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex.
Protein: FIO1_SCHPO
Sequence: MNKFFSFPILGLLLTCVRFVVAKERLFEWNVTDVYDVDPDGSGNSRWVIGVNNKWPIDPLVVDYGDQVIIKMTNSLANNRTTSLHSHGLFQKFTPYMDGVPQSTQCEIPPGATFYYNYTALQNGTYWVHSHDMSQYPDGLRTPFIINALEEPYDYDEEYIISMTDWYYTPFNILVPDEFKTWKNPTGAEPVPDTGLFNDTANATFAMEPGKTYRLRFINIGAFNNYDVMIEDHNMTIIEVDGEYTEPQEVSSIHLTVAQRYSVLVTAKNSTDRNYAITAYMDESLFDTIPDNYNPNVTAWLSYNSDASYDLGPDIDEIDSYDDAELNPLYSWDVTESNHSINIWFDFFTLGDGANYAEINDSSYVFPKVPSIMIANSTNVDGYNLEPVTYGPYTNAYIFEYGDVVDVIIDNHDTGKHPFHLHGHTFQVLERGEENAGLYSDQESHTYYDNPMRRDTVEIEPGSFIVIRFIADNPGAWVIHCHIEWHMESGLLATFIEAPEMIPSISSPDFVKEQCMLDGVPTIGNGAGNYKNISDLSGAPSPPGEMPAGWTSKAIGTMAACVISACIGMGSIIFYGASIHPVPTEELDENDDLQEAALENAAMFLDTDKAVEKVVEGKDEIK
What is the function of this protein?
Could be an iron transport multicopper oxidase, which is required for Fe(2+) high affinity uptake.  May be required to oxidize Fe(2+) and release it from the transporter.  Essential component of copper-dependent iron transport.
What are the official names of this protein?
Iron transport multicopper oxidase fio1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Protein: MGLL_MYCS2
Sequence: MVSSTRSEHSFAGVGGVRIVYDVWTPDTDPRGVVVLAHGYAEHAGRYHHVAQRFGAAGLLVYALDHRGHGRSGGKRVHLRDLSEFVEDFRTLVGIAANDHPTLPRIVLGHSMGGGIVFAYGARYPGEYSAMVLSGPAVNAHDGVSPVLVAVAKVLGKLAPGIPVENLDADAVSRDPEVVAAYKADPMVHHGKLPAGIARALIGLGQSMPQRAAALTAPLLVVHGDKDRLIPVAGSRLLVDRVASEDVHLKVYPGLYHEVFNEPEQKLVLDDVTSWIVSHL
What is the function of this protein?
Contributes to cell growth, probably by hydrolyzing exogenous lipids.  Catalyzes the hydrolysis of monoacylglycerols (MAG) with fatty acid chains ranging from C14 to C18, with a maximum activity on monoolein.  Is unable to hydrolyze long-chain diacylglycerol (DAG).
What are the official names of this protein?
Monoacylglycerol lipase, MGL.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: STXB2_MOUSE
Sequence: MAPLGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIADFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKAVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAGERGRQLDALAQQIATLCATLQEYPSIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSESREKAVLLDEDDDLWVELRHMHIADVSKKVTELLKTFCESKRLTTDKANIKDLSHILKKMPQYQKELNKYSTHLHLADDCMKHFKGSVEKLCSVEQDLAMGSDAEGEKIKDAMKLIVPVLLDASVPPYDKIRVLLLYILLRNGVSEENLAKLIQHANVQSYSSLIRNLEQLGGTVTNSAGSGTSSRLERRERMEPTYQLSRWSPVIKDVMEDVVEDRLDRKLWPFVSDPAPVPSSQAAVSARFGHWHKNKAGVEARAGPRLIVYIVGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKTLDQKLEGVALP
What is the function of this protein?
Involved in intracellular vesicle trafficking and vesicle fusion with membranes.  Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion.  Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity).
What are the official names of this protein?
Syntaxin-binding protein 2, MUSEC1, Protein unc-18 homolog 2, Munc18-2, Unc18-2, Protein unc-18 homolog B, Unc-18B.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: DAPP1_HUMAN
Sequence: MGRAELLEGKMSTQDPSDLWSRSDGEAELLQDLGWYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEPSIYESVRVHTAMQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIRSRSFIFK
What is the function of this protein?
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
What are the official names of this protein?
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, hDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Protein: TLXNB_HUMAN
Sequence: MAPLQLLHPWGRRGAWASQHSLLSQEAMGPGEGAEPTPWGYLRAEHWGASPSGAPTLPFAPDECSLTPGSPPHPLNKQKHHPPHPSQTQKDLVPRSPQLEKSRIRLRRTLRNLGGGRGQRGQ
What are the official names of this protein?
Putative TLX1 neighbor protein, TLX1 divergent gene protein.
Protein: MURI_ECO8A
Sequence: MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPYGEKSEEFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPALREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFETLEKLAVLG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y4FD_SINFN
Sequence: MTQETLRKLWITLAILTLVVMINIHGSTQKSDFALIIKLPIELKFDGELTREAYAVHGMRFFALFFWLVPFLAVYHAKRSSGSASEAFPFRLLDIEPRSRPGKWVQGIAFVVLICLPLLTAIHLWRIVVGMQVCQHVSNALVNCADIWSRPVNAGPWDDTYRLANWGPTYDPLVEPVLAVILTAVSVYLTLRLVIEMRRAGSRPVATGNTPAEPITTSVT
What are the official names of this protein?
Uncharacterized protein y4fD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCUP_PSEA8
Sequence: MTALKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRATRAKAGDFMSLCMNPELACEVTLQPLDRYPQLDAAILFSDILTIPDAMGQGLYFETGEGPRFRKVVSSLADIEALPVPDPEQDLGYVMDAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKSKAMLYDNPQAMHALLDKLAQSVTSYLNGQIHAGAQAVQIFDSWGGSLSAAAYQEFSLTYMRKIVDGLIREHDGRRVPVILFTKGGGLWLESMAEVGAEALGLDWTCDIGSARARVGERVALQGNMDPSVLYANPAAIRAEVARILAAYGKGTGHVFNLGHGITPEVDPAHAGAFFEAVHELSAQYHG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROCA_STAES
Sequence: MVVPFKNEPGIDFSVQTNVERFNEELRKVKAQLGQDIPLVINGEKLTKTDTFNSVNPANTSQLIAKVSKATQDDIEKAFESANHAYQSWKKWSHKDRAELLLRVAAIIRRRKEEISAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMELADGKPVLDREGEHNRYFYKPIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTVLTAYKLMEILEEAGLPQGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQQFLKRVIAEMGGKDAIVVDNNVDTDLAAEAIVTSAFGFSGQKCSACSRAIVHQDVHDEILEKAIQLTQKLTLGNTEENTFMGPVINQKQFDKIKNYIEIGKKEGKLETGGGTDDSTGYFIEPTIFSGLQSADRIMQEEIFGPVVGFIKVKDFDEAIEVANDTDYGLTGAVITNHREHWIKAVNEFDVGNLYLNRGCTAAVVGYHPFGGFKMSGTDAKTGSPDYLLNFLEQKVVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: PXPA_CUPTR
Sequence: MQIDLNADLGEGCGNDEALLALISSANIACGWHAGDAATMVQTVKWALARGVAIGAHPSYPDRENFGRTEMQRDPEHVYADVLYQIGALDAIVRAQGGVLHHVKPHGALYNQAVRDPALARAIVRAVRDFDADLVFFGLAGSQMIDVAKEAGLRVKQEVFADRGYNADGTLVRRGTPGALHEDEEVALDQTLTMVREQRVRAIDGTWVPIRAETVCLHGDGAHALAFARRIRERLGAEGIAIRAGD
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: F171B_MOUSE
Sequence: MARLCRRVPCALLLGLAAVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQLQEQKQREEAEEGRPEVPGASSTLVAPVSVFMLKVQVNDIVSRQYLSQAVVEVFVNYSKTNSTVTRSNGAVLIKVPYQLGLSLTIVAYKDGYVLTSLPWKTGRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKAFIKLPDNHHISNVTGYLTVLHQFLKVDSFLPATGVTYKSGLENVELTPHAAICVKIYSGGKELKVDGSIHVSLPLLHTSNIKIGDRIPAWTFDMNAGVWVHHGWGTVKEHNSHLIWTYDAPHLGYWIAAPSPATLDFGINDDFQDITAYHTVFLTAILGGTIVIIIGFFAILLCYCRGKCATPQKRERNITKLEILKRDQTTSTTHINHISSVKTALKAEDKPQLFNAKTSSYSPQRKETTKTEAEERISMVKTRDNFKIYNEDVSFLSVNHNYSRNPTQSLEPSMGSKQPKHINNNLSPSLGDAQEEKRYLTGTEEVYGRSHIPEQLMHIYSQPIAILQTSDLFSMPEQLHAAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPMHSHVQAPDAREEDIVLEGQQSLPSQTSDWSRYSNSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNEHQSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILEGGSGVIIEHPGEESPGRKSTVEDFEANTSPTKKRGRPPPLAKRDSKTNIWKKREERPLIPLN
What are the official names of this protein?
Protein FAM171B.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RIBBA_ACTP2
Sequence: MTDFQFSKVEDAIEAIRQGKIILVTDDEDRENEGDFICAAEFATPENINFMATYGKGLICTPISTEIAKKLNFHPMVAVNQDNHETAFTVSVDHIDTGTGISAFERSITAMKIVDDNAKATDFRRPGHMFPLIAKEGGVLVRNGHTEATVDLARLAGLKHAGLCCEIMADDGTMMTMPDLQKFAVEHNMPFITIQQLQEYRRKHDSLVKQISVVKMPTKYGEFMAHSFVEVISGKEHVALVKGDLTDGEQVLARIHSECLTGDAFGSQRCDCGQQFAAAMTQIEQEGRGVILYLRQEGRGIGLINKLRAYELQDKGMDTVEANVALGFKEDEREYYIGAQMFQQLGVKSIRLLTNNPAKIEGLKEQGLNIVAREPIIVEPNKNDIDYLKVKQIKMGHMFNF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: HEM3_CORDI
Sequence: MTLKIGTRGSLLATTQSGHVRDDLRPYEAELVIVTTHGDVNMAPVERIGVGVFTQALREELHTGGCDIAVHSFKDLPTELDPRFHLVVPKRADFRDCLIARDGLSLADLPAGALIGTGAPRRISQIKALRPDVECVPLRGNIDTRMGKVTSGELDAVVLAYAGLTRVGRGDEATQVFDPQDFLPAPAQGALAVECRADDAYAREAIDSICDEQAQVCAVTERVVLNRLEAGCTAPVAAHATLNDGTLTLTAAVIALDGSKVVRRELSAPVAENVALAEELTRALIADGAATILG
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ECTC_STRCO
Sequence: MIVRSFKEFEGTDRHVKSASGTWESTRIVLAKEKVGFSVHETILYAGTETSMWYANHIEAVVCTKGDAELTDRETGKTYHITPGTMYLLDGHERHTLKVKEDFHCICVFNPPVTGREDHDENGVYPLLTEEV
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: NOT2_XENLA
Sequence: MLHSPVFPAFGHHLADYPAMPLATDLPRTPKSSFNIDSILSRTDRPASKVSMEMPSWQPPSPPFHYSYGMVPYPPMWLIKPTVGYPNMAQAQPMRMPRGECLCPDPACKHRGLSYSHCPNGALNPLSWRTGPCKLKRIRTVFTPEQLERLEKEFLKQQYMVGTERVDLASTLNLTETQVKVWFQNRRIKWRKQSLEQKKAKLSQFGVILADSSDHTDDSRETEEEEDDVDVEL
What is the function of this protein?
Transcriptional repressor (By similarity).  Plays a fundamental role in notochord formation, acting within the mesodermal region.  Acts downstream of gsc and upstream of chrd and foxa4-A/pintallavis.
What are the official names of this protein?
Homeobox protein not2, Xnot-2, Xnot2.
What are the subcellular locations of this protein?
Nucleus.
Protein: OP21A_ARATH
Sequence: METSLRYATNSRSLKIHAKEKFPVNSKTRLQLHGELDTGAGVPSYFCAMIRYFFHEASTNLGVGLHYDKREKLRCLVRGKKKFPVITDEVVTFNIKGRCDFDQDLVQRNAKGAAEFDWNIWKFQKDQDLRLRIGYEMFEKVPYMQIRENNWTFNTNLKGKWNVRYDL
What is the function of this protein?
Voltage-dependent rectifying anion channel that facilitates the translocation between chloroplast and cytoplasm of phosphorylated carbohydrates such as triosephosphate, 3-phosphoglycerate and inorganic phosphate (Pi) depending of ATP to triosephosphate ratio in the plastidial intermembrane space; in high triosephosphate/ATP conditions (e. g.  photosynthesis), export of triosphosphate from chloroplast (outward rectifying channels), but in high ATP/triosephosphate conditions (e. g.  dark phase), import of phosphosolutes (inward rectifying channels) (By similarity).
What are the official names of this protein?
Outer envelope pore protein 21A, chloroplastic, Chloroplastic outer envelope pore protein of 21 kDa A.
What is the protein family that this protein belongs to?
Belongs to the plastid outer envelope porin OEP21 (TC 1.B.29) family.
What are the subcellular locations of this protein?
Plastid, etioplast membrane; Multi- pass membrane protein. Plastid, chloroplast outer membrane; Multi-pass membrane protein. Note=Present in non-green root plastids.
Protein: PESC_CULQU
Sequence: MVKRNHKFQSGEGAQYLTRKAAMRKLQLSMQDFRRLCILKGIYPREPKHRAIAQRGSTDIKILYHKKDITFLLHEPIVWTLRDRKIFNRRIAAAKGKGNNLLKNVRMANYPEIKLDHIIKERFPTFVDAIKELDDCMTLLFLFSTFPAMKTVTRDITSMARRLSIEFMHYCIASKALRKVFVSIKGYYFQAEIKGELVTWIVPHYYPYQPQRKEYVDFKIMKSFADFFTVMAGFVNFRLYNSINLVYPPQFSVSLDSEESRSNEDTFISERIAALNSDLLRSDQMGTEEEDDQIDLDLLDGDKDSEQVRKLREDAVSLNKLKNLFKGLKFFINREVPREPLVFILRCFGGRASWDRNLFVGATFDESDETITHQIVDRPSLPKQYISRDYVQPQWIFDCVNQRKLLPVNKYLIGAVLPPHLSPFNRDDAIYVPPEEAALRDGVELDAGARNGEERISDDEDEDAEQRQQVQLDYALVKAFREEKTEALNSGALEEAPEEEDDDEEAPEEDEQTKQKNEKKKKMAVVSGKIFKENPSEQKKLTKQEEALRARMVKSRHKKLYRKMLEKQKKQTKEANLLKEKRQQIDKKQRVEQTQKRKTQRKEILAK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ILVN_ECO57
Sequence: MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ
What are the official names of this protein?
Acetolactate synthase isozyme 1 small subunit, Acetohydroxy-acid synthase I small subunit, AHAS-I, ALS-I.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: TRPG_THEKO
Sequence: MIVLVNNRDSFVWNLAEYASLFDRVKVVPNTITVGELRRLDPDGVIISPGPGHPLERREVGNSPEIVLEAGVPILGVCLGHQIIATAFGGKVGRVKPRHGKASPVKHDGKGVLRGIKNPLTAGRYHSLAVLEVPREFDVSAVSLDDNVVMGIRHRKLPIEGLQFHPESVLTEWERKEGLRIIKNFVEMSRNG
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: RL32_CALS8
Sequence: MAQPKRRWSKQRTHKHRANWKIEAPNLVECPQCHEMKLPHRVCPSCGYYKNRKVVNED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LYSC_LOPIM
Sequence: KVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVHAWIRGCRL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSP77_HUMAN
Sequence: MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFQVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPTYFSNSQRQATKDAGAIAGLKVLPIINEATAAAIAYGLDRRGAGKRNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTPSSSTQATLEIDSLFEGVDFYKSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDFVLGGGLHSHPQGAEVAAGLLQRQGAEQEHQP
What are the official names of this protein?
Putative heat shock 70 kDa protein 7, Heat shock 70 kDa protein B.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PG162_VAR67
Sequence: MKSLNRQTVSRFKKLSVPAAIMMILSTIISGIGTFLHYKEELMPSACANGWIQYDKHCYLDTNIKMSTDNTVYQCRKLRARLPRPDTRHLRVLFSIFYKDYWVSLKKTNNKWLDINNDKDIDISKLTNFKQLNSTTDAEACYIYKSGKLVKTVCKSTQSVLCVKRFYK
What is the function of this protein?
Forms a complex with OPG162 and OPG190 to coordinate the incorporation of OPG164 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails.  Therefore plays an essential role in efficient cell-to-cell spread of viral particles.
What are the official names of this protein?
Protein OPG162.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG162 protein family.
Protein: AROA_CHLPN
Sequence: MLTYKVSPSSVYGNAFIPSSKSHTLRAILWASVAEGKSIIYNYLDSPDTEAMICACKQMGASIKKFPQILEIVGNPLAIFPKYTLIDAGNSGIVLRFMTALACVFSKEITVTGSSQLQRRPMAPLLQALRNFGASFHFSSDKSVLPFTMSGPLRSAYSDVEGSDSQFASALAVACSLAEGPCSFTIIEPKERPWFDLSLWWLEKLHLPYSCSDTTYSFPGSSHPQGFSYHVTGDFSSAAFIAAAALLSKSLQPIRLRNLDILDIQGDKIFFSLMQNLGASIQYDNEEILVFPSSFSGGSIDMDGCIDALPILTVLCCFADSPSHLYNARSAKDKESDRILAITEELQKMGACIQPTHDGLLVNPSPLYGAVLDSHDDHRIAMALTIAALYASGDSRIHNTACVRKTFPNFVQTLNIMEARIEECHDNYSMWSTHKRKVFARESFG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.