PharMolix/UniProtQA huggingface dataset:
Protein: ESR1_ORENI
Sequence: MYPEESRGSGGVATVDFLEGTYDYAAPTPAPTPLYSHSTTGCYSAPLDAHGPLSDGSLQSLGSGPTSPLVFVPSSPRLSPFMHPPSHHYLETTSTPVYRSSHQPVPREDQCGTRDEAYSVGELGAGAGGFEMTKDTRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGMRKDRGRVLRREKRRACDRDKPAKDLPHTRASPQDGRKRAMSSSSTSGGGGRSSLNNMPPDQVLLLLQGAEPPILSSRQKMSRPYTEVTIMTLLTSMADKELVHMITWAKKLPGFLQLSLHDQVLLLESSWLEVLMIGLIWRSIQCPGKLIFAQDLILDRNEGTCVEGMAEIFDMLLATASRFRVLKLKPEEFVCLKAIILLNSGAFSFCTGTMEPLHDSAAVQHMLDTITDALIFHISHLGCSAQQQSRRQAQLLLLLSHIRHMSNKGMEHLYSMKCKNKVPLYDLLLEMLDAHRIHRPVKPFQSWSQGDRDSPTASSTSSSGGGGGDDEGASSAGSSSGPQGSHESPRRENLSRAPTGPGVLQYRGSHSDCTRIP
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTN3B_XENLA
Sequence: MAETSGPQSSHISSSSAGDKGSGCAVRDLLYWRDVKQSGMVFGGTMVLLLSLAAFSIISVISYLVLSLLSVTISFRVYKSVLQAVQKTEEGHPFKPLLEKDIALSSDSFQKGLSSSLAHVNHALKSIVRLFLVEDLVDSLKLALLMWLMTYIGAVFNGITLLILGVLLAFTTPLVYEKYKVQIDHYVSLVHSQVKSITEKIQAKLPGALKKKSE
What is the function of this protein?
May be involved in membrane trafficking in the early secretory pathway.
What are the official names of this protein?
Reticulon-3-B, RTN3.2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: YUAY_ECOLI
Sequence: MAIDIFQSLKNCVFDLQRADVQNYQQPLKQLARLLNSENLQSVNAHLTRNVELDTFLARSEDTESSMAGSAVLQWPDEPADILGLKLLLIEKMADDNNFSFNFCHTFFYDRNIIESIRKFTSSLVAPFVRDYQLYVENQHDPEPAVFRPVSRKIFIVHGHDNDALQSVARFISRIGLEEIILSERPDGSRTIIEKFEAESGDVSFAIVLMTPDDSGSALASESTRLRARQNVLYELGYFAGKLGRGKVLVLRKGDIEIPSDLAGVLYTELDEHGGWKRKLLSELAYAGVPFDKDKALSA
What are the official names of this protein?
Uncharacterized protein YuaY.
Protein: BRWD1_HUMAN
Sequence: MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIEKPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHKHRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDSQETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRKTKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ
What is the function of this protein?
May be a transcriptional activator.  May be involved in chromatin remodeling (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape.
What are the official names of this protein?
Bromodomain and WD repeat-containing protein 1, WD repeat-containing protein 9.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: STRK1_ORYSJ
Sequence: MFTGCGLFACVRRCDGGDVRKRGEAGAMSSRVAADPAGVEEEGSCKNVAAASARQLAWADVESVTGGFSSRVIGHGGFSTVYLASLSSSRLGAVKVHCSSERLHRAFRQELEVLLSLRHPHIVRLLGYCDERDEGVLVFEYAPNGDLHERLHCSEVAGGVASVLPWARRVAIAFQVAMALEYLHESRHPAVIHGDIKASNVLLDANMNAKLCDFGFAHVGFSATVGCRPSARAVMGSPGYVDPHLIRSGVATKKSDVYSFGVLLLELVTGKEAVCRDTGRRLTAAVGPMLSEGKVADVVDRRLGGEHDGAEAAVMAELAMQCIGDSPGLRPSMADVVRALQEKTSALASAVGSRLDRKMMF
What is the function of this protein?
Acts probably as a dual specificity protein kinase (Probable).  Regulates hydrogen peroxide (H(2)O(2)) homeostasis and improves salt tolerance by phosphorylating tyrosine residues of CATC thus activating its catalase activity.  Promotes growth at the seedling stage and prevents grain yield loss under salt stress conditions (PubMed:29581216).
What are the official names of this protein?
Salt tolerance receptor-like cytoplasmic kinase 1, Receptor-like cytoplasmic kinase 154, OsRLCK154.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYM_KINRD
Sequence: MTHVLSAVAWPYANGPRHIGHVAGFGVPSDVFSRYMRMAGHDVLMVSGTDEHGTPILVQAEQEGLTPQQLADRYNRVIAEDLHGLGLSYDLFTRTTTANHYAVVQEMFRTVHRNGYMVARKGMGAISPSTGRTLPDRYVEGTCPICGYDGARGDQCDNCGNQLDAIELKNPRSRINGETPVFVETEHFYLDLPALAEALGSWLQTRADTGRWRPNVLKFSQNLLADMKPRAMTRDIDWGIPVPLEGWEDNPAKRLYVWFDAVIGYLSASVEWARRSGDDDAWKAWWTDPAAESYYFMGKDNITFHSQIWPAELLAYDGRGSAGGQPGPFGNLNLPTEVVASEFLTMEGKQFSSSRGVVIYVRDVLARYQPDALRYFISAAGPENNDSDFTWQEFATRTNSELVAGWGNLVNRTASLIAKNVGEIPAAGELTDADRDLLATTSGGFSTVGGFIEAHRQRAGIGEAMRVVGEVNKYLTEQEPWKIKNSDPERMKSVLHVTAQAVSDCRTLLSPFLPHSAQKVHQAFGGVGTVSPLPELREVTDLDDGRPYPVLTGDYRRGETLPEWASHPVVPGTPVAAPTPVFTKLDVAAVVEEELGRLQR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_YERPE
Sequence: MKALHFGAGNIGRGFIGKLLADAGAQLTFADVNQPLLDELNKRKRYQVNVVGEQARVEEVKNVSAVNSGSPEVVALIAEADIVTTAVGPQILARIAATVAQGLITRHQQGNTRPLNIIACENMVRGTSQLKQHVFAALSEDEQIWVEQHVGFVDSAVDRIVPPSEAGSTDILAVTVETFSEWIVDGTQFKGQPPEIVGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPQKHAAYINKILSRFENPYLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYQLPHDSLVTGIAAAMSYRSEQDPQAQELVTLLAQLGPKAALAQISGLPADSEVVEQAVSVYNAMQQKLAH
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: ATPD_MARMS
Sequence: MAELKTVARPYAKAVFEVAREQGHIVEWADMLNVLASVTVEPKLKKALGNPAFSAEEKANALADVCAEVTTEQGKAFLLALAVNKRLSLLPAISELFLQFKLNFEKAVNVQFTSAFELTAEQTQALAASLAKKLDRTVNLTSETDASLIGGVVIRTGDLIIDGSVRGKLAKLAEAINS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL27_EHRCR
Sequence: MATKKSGGSSGNGRDSRGRRLGVKKFGSEKVIPGNIIIRQRGTKYHPGKNVGIGKDHTIFSKISGFVHFRKGVYNKTFVDVLEASSVS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MEND_SYNSC
Sequence: MQAALTLLEALCLQGLKQLVLCPGSRSGPLATAAGVLASQAKLQLVTAIDERSAAFLALGMATAHGRVVAVVTTSGTAVSNLLPAAVEADRSCQPLLLLTADRPVRLKNCGANQTVNQESFLLAACRWFGSGAADGIHTQANDALNALAVKAWQQAQGAGTGPPGAVHLNLPFEEPLHTTLEQQQQLASAALPPTACPEPSPGIGPALRLDPERPGVVVAGPWRGLTLSLEAHQQALHRWLNLSGWPLLADPLAALPPDCPNRIEHWELQLDRLSLPDDAQVLRLGPMPASRRLEAWLQRHQGPQLLITEGDPRPLDPLHTANQWSGGMAAWIAQQPGLKQATKPSVGTNDLSPWLETQLPLRGAVTEPALAYWLPQLLPEQLPVMLAASSPVRDWLTWGGYSCGRHRCFSFRGASGIDGTLSLAMGLAANLGPLALVTGDLALLHDSNGWLHASSAAAPPPLLVLLIDNGGGGIFQQLPIATPGFESLFAMPQQVDSLALAAAHGVPGRQVACLEDLQEALAWGLSQQRPVLLRLCSDRGRDAVLRQQLRAAAQNEGTEL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RL14_PERMH
Sequence: MIRRGTYLNTADNSGAKKVQCIGIPKKVNFGKQTDFATLGDVITVTVKDALPNGAAKKGKVYKAVVVRTAKEVSREDGSYIKFDDNAVVLLNNNLEPIGTRILGPVAREIRAKGFYRIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLMM_SHIFL
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVYGDQIMYIIAREGLRQGHLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGAGIVAGLQVLTAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDAAQVTEFAHRITDAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CRBA1_CHICK
Sequence: MGEAAVPPELDTFPAAKMAQTNPLPVPMGPWKITVYDQENFQGKRMEFTSACPNIMECGFDNIRSLKVECGAWVGYEHTGFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPVCSANHKESKITVYEKDNFIGRQWEISDDYPSLQAMGWANNEVGSMKIPCGAWVCYQYPGYRGYQYVLEADHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A3, Beta-crystallin A1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: PRP11_SCHPO
Sequence: MSRRTRSRSPPRRSYNRERRDYRKYDDSEDQKGARYNRYVDDVSSRRDRHDSFRSHESNKIRRDNSWKHDKYSYEKRYQERDREYARSKNIPDQYIGRSPRPTSHRHAEEKEVDNKTKSDETNPVLQGSATEIKPQPRRSRFDRTERVGASLSVSEIQSENPRVDVIPKDKAVENNHQRNAEKPVASDKITDAKLLARLERVRAWKESKAKQEASKKEEHKLNTKPQVTAKDQNAMPSTGISGFEINRQKDTSDMKRNNRVHMDDEDGPRRMNLEDYQELWDQEDRGMLGNEQAASMEEDEVDPLDAYMASLVGTTDTIRPGLLNTEVIDPNANDDERMVISETLEEEENLLALAAKRSKKKDVITVDHSKINYEDFKKDFYVEPEELKNLSPAEVDELRASLDGIKIRGIDCPKPVTSWSQCGLSAQTISVINSLGYEKPTSIQAQAIPAITSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLKTGEGPIAIIMTPTRELAVQIFRECKPFLKLLNIRACCAYGGAPIKDQIADLKRGAEIVVCTPGRMIDVLSANAGRVTNLHRCTYLVLDEADRMFDLGFEPQVMRIINNIRPDRQTVLFSATFPRAMEALARKVLKKPVEITVGGRSVVASEVEQIVEVRPEESKFSRLLELLGELYNNQLDVRTLVFVDRQESADALLSDLMKRGYTSNSIHGGKDQHDRDSTISDYKAGVFDVLIATSVVARGLDVKSLQLVVNYDCPNHMEDYVHRVGRTGRAGHTGVAVTFITPEQEKYAVDIAKALKMSKQPVPKELQTLASQFLEKVKAGKEKAAGGGFGGKGLSRLDETRNAERKMQRKAYGEDEEDVETEAEAKSPLEKITPEKSTGDPTLDRVRAAVGGIAARAFANQTAQSNKLTQPISIIKTDGDEYKAKMEINDYPQQARWAVTNNTNIVHVTELTGTSITTKGNFYLPGKNPEPGEEKLYLWIEGPSELVVNRAITELRRLLLEGINHSLEGGNKPSASGRYTVV
What is the function of this protein?
ATP-dependent RNA helicase involved in pre-spliceosome/complex A assembly and mRNA splicing (PubMed:14713954).  Bridges U1 and U2 snRNPs during pre-spliceosome assembly and enables stable U2 snRNP association with intron RNA (PubMed:14713954).  Through its helicase activity probably catalyzes an ATP-dependent conformational change of U2 snRNP (PubMed:14713954).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase prp11.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHE4_COREF
Sequence: MTVDEQVSNYYDMLLKRNAGEPEFHQAVAEVLESLKIVLEKDPHYADYGLIQRLCEPERQLIFRVPWVDDNGQVHVNRGFRVQFNSALGPYKGGLRFHPSVNLGIVKFLGFEQIFKNSLTGLPIGGGKGGSDFDPKGKSELEIMRFCQSFMTELHRHIGEYRDVPAGDIGVGGREIGYLFGHYRRLANQHESGVLTGKGLTWGGSLVRTEATGFGTVYFVQEMIKAEGETLEGKKVIVSGSGNVATYAIQKVQELGAVVVGFSDSSGWVSTPNGVDVAKLREIKEVRRARVSSYADEVEGAEYHTDGSIWDLTADIALPCATQNELDGDNARTLADNGCRFVAEGANMPSTPEAIDVFRERGVLFGPGKAANAGGVATSALEMQQNASRDSWSFEYTDERLHRIMKNIFKSCADTAKEYGHEKNYVVGANIAGFKKVADAMLAQGVI
What is the function of this protein?
Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: RSMA_HELPH
Sequence: MVVAKKSLGQHFLTDESFLDRIVDALPPLNPLKLVEIGVGLGDLTLKLLDRYPLKTYEIDSSLCEKMRSKLKVQKKPFKLELVEKDALFLKEEEPYFLISNLPYYIATRLVLNALKDPKCRGLLVMTQKEVALKFCAKDSQNALSVLAHAIGNATLLFDVPPSAFSPPPKVFSSVFEVIKESLKEKALASLAQVPFFEEALQKGFETLEDFLKACFSSPRKTLSNNLKKSVSYKEKLDKVLDFLALENQPTSVRASEIKDYLKLLNYLLKG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNRG_HUMAN
Sequence: MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
What are the official names of this protein?
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.
Protein: ANFC_TRISC
Sequence: MSGQTSFYCGLLLVLLIQAQARPRSDDSLQTLSRLLEDEYGHYLPSDELNNEAQEMSPAASLPEFNADQSDLELPWDRESREIGGRPFRQEAVLARLLKDLSNNPLRFRGRSKKGPSRGCFGVKLDRIGAMSGLGC
What is the function of this protein?
Hormone which may be vasoactive and natriuretic.  Has a cGMP-stimulating activity (By similarity).
What are the official names of this protein?
C-type natriuretic peptide prohormone, CNP-115.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSSA_TALMQ
Sequence: MAPSNLPPVFNATSQDIEMLLAAQCHLGSKNLQVHMEPYLWKTRPDGINVINIGKTWEKIVLAARIIAAIDNPADVAVISARPYGQRAVLKFASHTGATAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDAQAIKEASYVNIPVIALCDTDSPTEFVDVAIPTNNKGRHAIGLVWWLLAREVLRLRGTLATRETEWDVVVDLYFYRDPEAEETKEIADETKVAGAEEVGPAAIESGYVGDSWDAAAPGAAAPGAAFAAASATAGATWEAEASGDWAAESAQPNPETKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_SOLUE
Sequence: MGNVIILGSQWGDEGKGKIVDLFAERFDIVARYQGGHNAGHTVFIGEKKFVLKLIPSGILRPGKKAVIGNGLVIDPAALLSEIDTLQAAGVPVMGNLFISNRAHVLFPAHRMMEKMSEGREGRVSIGTTSRGIGPCYEDKIARRGIRIADLLDTEFFRAQYASVMEEKVLIAKALGIYSELDLRAIRDEYEAFAERIRPMVCDTSVLLNDAIRSGKTVMFEGAQGTMLDIDHGTYPFVTSSSASAGGACTGTGVAPTRISGVLGVSKAYITRVGGGPFPTEAFDGAGDRIRERGKEFGAVTGRPRRCGWFDVPLLRYTANINGFDSLVITKLDVLDEFDQIPVCVSYRIGNREVVDMPPTVAEMEKVEPVYECVPGWNTSTFGISQFGELPAKAKEYLAYLENRTGVEVGCVSTGPERNQTIVRAGSRFESLIG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_CUPMC
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVKGPVPLPTRIQRFDILRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PUB50_ARATH
Sequence: MEETKTHELEVEAESGSRMEKVYIAVGNDVQEGYKTIHWALKKWNNIPISIVLLHLCNISQDFVYTPFGKLPASSVSEEKLQVLRKYEDQKIDKLLSKYITFCGKVCPLSVNFVLFGKSKSAISGSFYVYQNKPEFCEFYIICGGKMVSLKNDVNNNNSNIRSWIGKMFHDPGRNLDRSSGNNDDPTASGSSWDKNLQEIENYFQQLLSLNLAEEETENVVEEEQEDDDDVALNVLQHMDVAEKLEYVRRKVNEAKLMIDEKSREVKVNAERSNRAEWAISLCNSRIGEFEAWIKEESERREKLQATLDSDKECIEEAKNYVEKGKTKLHSLAELQEVLSSKVKTMMEAKSQAEVELERVVLQRGEMITEIEKLRSQRDVFNRRIEFCKEREVIGSVSKEEVKCGYREYVAEDIRLATETYSDRLRLKSGGNWTNVYRGRIKHTTVAVKVIGDSLSDEAFGAKVKLLNEIRHPNLVAIAGFCSQRPKCLLFEYMHNGNLRDNLFTSQRKSRRSKILKWHDRIRIAHQVCSGLGFLHSVKPKPIVHGRLTPSKILLDRNLVPKITGFGLIMHSDQSDTKPDVMAFGVLLLHLLTGRNWHGLLKAMSMNQTSILRDLDQTAGKWPLELAKEFGALAVKCSSVNRGGNMDFSTKEIMEELGKIREKADEFKTKGGYEEATNSNMDEGDPNDIPSVFMCPILQEVMKNPHVAADGFSYELEAIQEWLSMGHDTSPMTNLRLDYQMLTPNHTLRSLIQDWHSKRAAQASS
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
Putative U-box domain-containing protein 50, Plant U-box protein 50, RING-type E3 ubiquitin transferase PUB50.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: AP2_ARATH
Sequence: MWDLNDAPHQTQREEESEEFCYSSPSKRVGSFSNSSSSAVVIEDGSDDDELNRVRPNNPLVTHQFFPEMDSNGGGVASGFPRAHWFGVKFCQSDLATGSSAGKATNVAAAVVEPAQPLKKSRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNIDDYDDDLKQMTNLTKEEFVHVLRRQSTGFPRGSSKYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPSIYDEELNAESSGNPTTPQDHNLDLSLGNSANSKHKSQDMRLRMNQQQQDSLHSNEVLGLGQTGMLNHTPNSNHQFPGSSNIGSGGGFSLFPAAENHRFDGRASTNQVLTNAAASSGFSPHHHNQIFNSTSTPHQNWLQTNGFQPPLMRPS
What is the function of this protein?
Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989).  Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158).  Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631).  Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158).  Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631).  It is also required during seed development (PubMed:1675158).
What are the official names of this protein?
Floral homeotic protein APETALA 2.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXM_HAEIN
Sequence: MSDNQQNLRLTARVGYEAHFSWSYLKPQYWGIWLGIFFLLLLAFVPFRLRDKLTGKLGIWIGHKAKKQRTRAQTNLQYCFPHWTEQQREQVIDKMFAVVAQVMFGIGEIAIRSKKHLQKRSEFIGLEHIEQAKAEGKNIILMVPHGWAIDASGIILHTQGMPMTSMYNPHRNPLVDWLWTITRQRFGGKMHARQNGIKPFLSHVRKGEMGYYLPDEDFGAEQSVFVDFFGTYKATLPGLNKMAKLSKAVVIPMFPRYNAETGKYEMEIHPAMNLSDDPEQSARAMNEEIESFVTPAPEQYVWILQLLRTRKDGEDLYD
What is the function of this protein?
Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
What are the official names of this protein?
Lipid A biosynthesis acyltransferase, Kdo(2)-lauroyl-lipid IV(A) acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CARA_CORGL
Sequence: MSKDTTTYQGVTEIGSVPAYLVLADGRTFTGFGFGAIGTTLGEAVFTTAMTGYQETMTDPSYHRQIVVATAPQIGNTGWNDEDNESRDGKIWVAGLVIRDLAARVSNWRATTSLQQEMAGQGIVGIGGIDTRALVRHLRNEGSIAAGIFSGADAQRPVEELVEIVKNQPAMTGANLSVEVSADETYVIEAEGEERHTVVAYDLGIKQNTPRRFSARGVRTVIVPAETPFEDIKQYNPSGVFISNGPGDPAAADVMVDIVREVLEADIPFFGICFGNQILGRAFGMETYKLKFGHRGINVPVKNHITGKIDITAQNHGFALKGEAGQEFETDFGTAIVTHTCLNDGVVEGIALKSGRAYSVQYHPEAAAGPNDASPLFDQFVELMDADAQKKGA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: GPPA_SALHS
Sequence: MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAGLNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTEQANRVAKLADNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLQALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.