PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_BACAN
Sequence: MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATP25_CANAW
Sequence: MIVRGKCLGRSVSKAVSLFSRPISVISAKSFATTTNLLQNSKDDSTEATIPWYMREENSSPVEVLNKIEVPELPENSPQSLQEFVTLLTVEYGLTDLEIFDLSQLPEDHPKSLEEQNEENYVILASGKSEKHIYKAAYELRLYIKHTYKHLPIIEGMSSNSISKVTRRRLAKRVRRGPPATASTFGIGANSWVSCGTGVDGIVIHLLSRERRESLNLEQLYSDEQENEESHSTPEIDQNRLFFGDRRGFHTSSRNFNLNTLSNIYDSYVIDGNFDTSQKFKAQFDLNFKGGSVEEHNKKFELYRAINLVNANVVEANEIEQIIWDKYSSLDLALQQEIDWNTEIIKDTIKYMEFLVDLNARHSPREKLDKLSGFISNITCFAGDSIDLFTIDKFGALLWRLTWVSENNNALDSANLNEIIKRKGDFEPGTNTISFDNELGRNIRELLRQNKYSSNKETFPLWLREQMMYTFGQAGLWDRFWRDWQSILQSLNKTNERIYFWVVTALFLSKVDNRDALRHLFTKYWSNPSGASFVADYTTNNHQFNSDNERMALKNVLVQIGEKYNTSPWAREAAQFADNL
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1246_BURMA
Sequence: MDIALDLQSIAVQEKTLVFPQFDAARAWALGSQLREFALARGHAVAIDVRTFGQPLFFALVDGATPDNVDWARRKGNVVAHFRRSSYAIGLRLQQAGATLADKHGLPAAEYASHGGAFPIAVAGAGVIGSVTVSGLPQRGDHELVVEALCAQLGHAYATLALTGN
What are the official names of this protein?
UPF0303 protein BMA1246.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: VPS39_ARATH
Sequence: MVHNAYDSFQLLKDCPARIDAVESYGSKLFAGCYDGSLRIYSPPESSASDPSELHQETYVLEKTVAGFSKKPIVAMEVLASRELLLSLSESIAFHGLPNLETVAVITKAKGANAYSWDDRRGFLCFSRQKRVCVFKHDGGGGFVEVRDYGVPDTVKSISWCGENICLGIKKEYVILNTANGTLSEVFPSGRVAPPLVISLPSGELILGKENIGVFVDQNGKLLQTERICWSEAPTSIVIQNPYAIALLPRRVEVRLLRSPYPLIQTIVLQNIRRLVKSNNAVIVGLDNSVYVLFPVSIGAQIVQLTASGNFEEALALCKVLPPDESSLRAAKESSIHTRFAHYLFENGSYEEAMEHFLASQVDITHVLSMYPSIILPKTTIIPQPDKMVDISGDEASLSRGSSGISDDMESSSPRYFLESEDNADLESKKMSHNTLMALIKYLLKRRPAVIEKATSEGTEEVISDAVGKTYGANDSSKSKKSSKGRGMIPLNSGAREMAAILDTALLQALLHTGQSGAAIELLKGVNYSDVKICEEILMKSKNYSALLELFKSNSMHHEALKLLNQLADESKTNQSQTDVTQIFSPELIIEYLKPLCRTDPMLVLEYSMLVLESCPTQTIDLFLSGNISADLVNSYLKQHAPNMQGRYLELMMAMNDTAVSGNLQNEMVQIYLSEVLDLYAAKSAQQKWDEKDHPPERKKLLSALESISGYSPQPLLKRLPRDALYEERAVILGKMNQHELALSIYVHKLHAPDLALAYCDRIYESVTYLPSGKPSSNIYLTVLQIYLNPKKSAKDFAKRIVALGSFESSDTTKMMDSVLSSKAKGGRSKKIVAIEGAEDMRVGLSSSTDSGRSDVDTEEPLEEGDSTVMISEVLDLLSQRWERINGAQALKLLPRETKLHNLLPFLAPLLRNSSEAHRNFSVIKSLRQSENLQVKEELYKHRKGVAQVTSESMCSLCNKKIGTSVFAVYPNGKTLVHFVCFRDSQGMKAVSKTTHGRRR
What is the function of this protein?
Essential protein required during embryogenesis (PubMed:15266054, PubMed:29463724).  Believed to act in part as a component of the putative HOPS endosomal tethering complex.  HOPS is required for the central vacuole formation (PubMed:29463724).  May play a role in clustering and fusion of late endosomes and lysosomes.  Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways.  Required for fusion of endosomes and autophagosomes with lysosomes (By similarity).
What are the official names of this protein?
Vacuolar sorting protein 39, Protein EMBRYO DEFECTIVE 2754.
What is the protein family that this protein belongs to?
Belongs to the VAM6/VPS39 family.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Note=Co- localizes with VPS18 and RABG3F at subdomains of the vacuolar membrane with a small number of punctate structures in the cytoplasm. Sometimes observed at the vertex zone, the ring-shaped edge of vacuole-vacuole contact sites. Strong colocalization with VAMP713 at the contact sites of two vacuoles.
Protein: HUTG_STAES
Sequence: MYQLAQSNLWTGRLDSETDPTQFRHFQTVKFGDLSQLDFSDEHKGVGLLGYAIDKGVELNKGRVGAKEGPNAIKRAFAGLPDLNQCEEIIDYGNVEHNHELLIDTQREFADLAAKSIKRHKQTFLLGGGHDIAYAQYLATRKVYPESSIGVINIDAHFDTRDEGYSTSGTSFRQILEEDDNADYLVLGISQGGNTQALFNYAKEKDIQFVYADELLHQVSPPIKDMIERFIHNHDTVMFTICMDVVDSAFAPGVSAPAVLGIYPHTVFELAKRVIPSEKVKSISIAEMNPTYDSDQRTAKLVANLVHHCLI
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GH_HCMVT
Sequence: MRPGLPSYLIVLAVCLLSHLLSSRYGAEAISEPLDKAFHLLLNTYGRPIRFLRENTTQCTYNSSLRNSTVVRENAISFNFFQSYNQYYVFHMPRCLFAGPLAEQFLNQVDLTETLERYQQRLNTYALVSKDLASYRSFSQQLKAQDSLGEQPTTVPPPIDLSIPHVWMPPQTTPHGWTESHTTSGLHRPHFNQTCILFDGHDLLFSTVTPCLHQGFYLIDELRYVKITLTEDFFVVTVSIDDDTPMLLIFGHLPRVLFKAPYQRDNFILRQTEKHELLVLVKKDQLNRHSYLKDPDFLDAALDFNYLDLSALLRNSFHRYAVDVLKSGRCQMLDRRTVEMAFAYALALFAAARQEEAGAQVSVPRALDRQAALLQIQEFMITCLSQTPPRTTLLLYPTAVDLAKRALWTPNQITDITSLVRLVYILSKQNQQHLIPQWALRQIADFALKLHKTHLASFLSAFARQELYLMGSLVHSMLVHTTERREIFIVETGLCSLAELSHFTQLLAHPHHEYLSDLYTPCSSSGRRDHSLERLTRLFPDATVPTTVPAALSILSTMQPSTLETFPDLFCLPLGESFSALTVSEHVSYVVTNQYLIKGISYPVSTTVVGQSLIITQTDSQTKCELTRNMHTTHSITAALNISLENCAFCQSALLEYDDTQGVINIMYMHDSDDVLFALDPYNEVVVSSPRTHYLMLLKNGTVLEVTDVVVDATDSRLLMMSVYALSAIIGIYLLYRMLKTC
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans- Golgi network (TGN).
Protein: FABZ_CHESB
Sequence: MADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFPERPVMPGVLIIEAMAQTAGAICIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKKVKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y092_MYCBO
Sequence: MDQPWNANIHYDALLDAMVPLGTQCVLDVGCGDGLLAARLARRIPYVTAVDIDAPVLRRAQTRFANAPIRWLHADIMTAELPNAGFDAVVSNAALHHIEDTRTALSRLGGLVTPGGTLAVVTFVTPSLRNGLWHLTSWVACGMANRVKGKWEHSAPIKWPPPQTLHELRSHVRALLPGACIRRLLYGRVLVTWRAPV
What are the official names of this protein?
Uncharacterized methyltransferase Mb0092.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: AROC_BURCM
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMGLTEADIQFELDRRKPGTSRHVTQRQEADEVEILSGVFEGVTTGTPIALLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPIVGAGAVAKKWLRERFGVEVRGYMSCLGEVDVPFVDWSHVRENPFFSPNAAIVPELEAYMDALRKDGDSIGARIDVVASGVPVGWGEPVFDRLDADIAKAMMSINAVKGVEIGAGFDSVAQRGSVHGDELTPAGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITKAGEEATVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVETSTPKIAGSAT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RPOA_THETH
Sequence: MLDSKLKAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYIEDVLHEFSTIPGVKEDVVEIILNLKELVVRFLNPSLQTVTLLLKAEGPKEVKARDFLPVADVEIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPVRRVAFQVEDTRLGQRTDLDKLTLRIWTDGSVTPLEALNQAVEILREHLTYFSNPQAAAVAAPEEAKEPEAPPEQEEELDLPLEELGLSTRVLHSLKEEGIESVRALLALNLKDLKNIPGIGERSLEEIKEALEKKGFTLKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PYRG_LACPL
Sequence: MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGTETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLQKERRGDYLGATVQVIPHITNAIKEKIMRAGTTTDSDIVITEIGGTVGDIESLPFIEALRQMKSDLGSDNVFYIHTTLIPYLRAAGEMKTKPTQHSVKELRSYGIQPNMLVVRTEQPITREMRNKIASFCDVEPEAVIESLDVKTIYSIPLNVQKQNMDQIVLDHFDVQAPKADMSEWIDLEHHVQNLSRTIKIALVGKYVALQDAYISVTEALKHAGYTDDADIDLKKISAEDVTPENVEELLGDADGILVPGGFGDRGIEGKITAIKYARENDVPFLGICLGMQMASVEFARNVLGLKDANSAEIDPKTPDNIIDLMADQEDVEDMGGTQRLGAYPCKLKPGTVAAKAYHNEEVVMERHRHRYEFNNKYREAMAAKGMVFSGTSPDNRLVEVIELPKKRFFVASQYHPEFLSRPNRPEGLFKAFIDAANQTGKVKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS3_CORJK
Sequence: MGQKIHPHGLRLGITSEWRSRWYADKQYADYLAEDIKIRDFLSEGLDRAGIANVVIERTHDRVRVDIHTARPGIVIGRRGSEADRIRGQLEKLTGKQVQLNILEVKNIDANAQLVAQSIAEQLTNRVAFRRAMRKAIQGAMRQPQVKGIKVVCSGRLGGAEMGRTERYHEGRVPLHTLRAEIDYGTYEAHTTFGRIGVKVWIYKGDVVGGRRESLMNARDERPSRGRRERPRRGGARRQRAEQKQEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PACC_FUSO4
Sequence: MSPPAPEQKPQLQQQQQQGSSSGDSSSGSANDSKSVTPAPSATSNTSQSSTAPSTSSDDNLICRWNACNQKFPAPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKSFKRPQDLKKHVKTHADDSVLVRPSQDPQGGLNYRPQPPKGPSSYYDHTGQMRTNAAAFAHQAGHPSGGYYAPQPSTNYGLYFNQPPINNARTEHLGYSAAAGGYDRKRTYDMVDDFFGSAKRRQIDPSSYAQIGRSLMPLHGNLSVPNGPMTATEQYMPQPAPAPVHAGPTPSKTPSAQQYYLPMPSARTQKDLIHIDTILGQMQDTIYENANHATAGVHIHHAENGFNGYRNTPSPPTSHRSPTGMHVGADGYQPVSAASMASPLTAISSTGTPAVTASSSMSYTSGHSPSPSSSAMSPQSRHGSTASVMYPTLPTSLPAVSQGFGHSATTTLGPSFDGSERRRYSGGMLQRARAGPLPLPHEDTSGASTPKASESALSVGSPSSESDVSDATREREEQYDRWLENMRVIETLREYVRGRLERKEFVDDNESPRSSHSDAMDVDPKSPQAPPRELGTPREGSSLYPILRMPGA
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes.  Specifically recognizes and binds the consensus sequence 5'-GCCARG-3'.  May act as a negative regulator of virulence to plants.
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KPRS_XYLFT
Sequence: MPTIQDERNLMVFSGNANKPLTQSICKELGVRMGKSLVSRFSDGEEQVEIEESVRRQEVFVVQPTCAPSAENLMELLVIIDALKRASVSSVTAVIPYFGYSRQDRRMRSLRVPITAKVAAKMISAIGADRVLTIDLHADQIQGFFDVPVDNVYASPLLLADIWRAYGTDNIIVVSPDVGGVVRARAMAKRLGDTDLAIIDKRRPRANVATVMNIIGEVNGKTCVLVDDLVDTAGTLCAAAVALKQNGATKVVAYITHPVLSGPAMDNINNSELDELVVTDTIPLSDAARECRKIRQLSVAELLAETIRRIAFGESVSSLYVD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_BUCAP
Sequence: MSYSLPDLSYAYNALEPFFDEETMRIHHTKHHQNYINNTNSILERTNFSSLSIEELMSIFNEISLENKNVLRNNAGGHINHSLFWKGLKIGTILQGDLKSEINKQFGSVEYFKSKFEDIALNHFGSGWIWLVNQNGILSIVSTINQDNPLMGKSISGTHGNPIFGLDLWEHAYYLKYQNRRLDYIKSFWNVVNWDEASRRLSK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SYV_PARMW
Sequence: MPELAKTYDPVGTEARWQQAWEDQGAFHPDPKAPGEPFSVVIPPPNVTGSLHMGHAFNTALIDTIVRYQRLAGKNVLCLPGTDHASIAVQTILEKQLKQEGKTRHHLGRDGFLERAWQWKAESGGRIVGQLRRLGYSVDWQRQRFTLDEGLSEAVKEAFVRLHEQGLIYRGEYLVNWCPASGSAVSDLEVEMKEVDGHLWHFRYPLSSGDGHLEVATTRPETMLGDTAVAVNPTDERYAHLVGQTLTLPFVGREIPIVADDHVEKDFGTGCVKVTPAHDPNDFAIGQRHGLPQITVMRKNGTMNKEAGQFEGLDRFEARKAVVAGLDELGLLVKVEDYRHSVPYSDRGKVPVEPLLSTQWFVRTEPLAARCREALEKQDPRFIPERWEKVYRDWLTDIRDWCISRQLWWGHRIPAWFVISETGGKYTDTTPYVVARNEVEALEKAKAKYGAAAVIEQDEDVLDTWFSSGLWPFSTLGWPDAESADLQRWYPTSTLVTGFDIIFFWVARMTMMAGAFTGEMPFQDVYIHGLVRDEQNRKMSKSAGNGIDPLLLIDRYGTDALRFALVREVAGAGQDIRLDYDRKTDTSATVEASRNFANKLWNATRFALMNLGDETPAQLGDPDPAALQLADRWILSRLARVNRETAERYSNYGLGEAAKGLYEFAWNDVCDWYLELSKRRLNPGENPSAEALADQRVAKQVLAKVISQMHQMLHPLMPHLTEELWHSVTGKSETTFLALQPWPALQESALDDALEASFADLIGAIRVVRNLRAVAGLKPSQSVPVRFVTGRGELAAVLNQGTADITALTRAESVAVMAPAEADAAPVAKALAGVSGELQVLLPIEGLVDLDALKGRLEKDIAKAEKEIKGLAGRLGNPNFADKAPPEVVAECQANLDEKQAQADLARKRLADLS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIP_SOLLC
Sequence: MAACSRRGNSLVVLAIVLLGCLSALSNAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDNERLIGEAAKNLAAVNPERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVSKDGKPYIQVKIKDGEVKVFSPEEISAMILTKMKETAEAFLGKTIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLATNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRSLSSQHQVRVEIESLFDGTDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPSKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKFIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRNLGKFDLTGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKAEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKEKIDARNALETYVYNMKNQINDKDKLADKLESDEKEKIETATKEALEWLDDNQSAEKEDYDEKLKEVEAVCNPIITAVYQRSGGAPGGGASEEEDDSHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein, BiP, 78 kDa glucose-regulated protein homolog, GRP-78.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LPXB1_LEGPH
Sequence: MPNASRVVIVAGEESGDHHAAELVKQLKAVYPDLEISGIGGKHLRAAGVHLISDLTRYAVTGLTEIIPFLKIFRKAFQDIKQHLSTQKPDLLILVDYPAFNLRLAKYAKKKLGIKIIYYISPQIWAWKGKRIHLIKDCIDKMAVIFPFEKTIYENAGVPVSFVGHPLVKKIAAAKDKHSGRTSLGLPLNEPIIALLPGSRHSEIERHIPILVNTAKLLTLDNPKLRFVVPIAGTINPDKVKAYFSNQNLTVTFIQGQAIECMSAADFVIVASGTASLECALLEKPMCIIYKSSFLTYVAAMYFIKVKFLGLCNLLANKMMVPEFLQYDCNAIELSRYISNFHNDPNQAKSMINQLAKLKESLSSSQADCSLFDLVVAELPEKNA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ACCA_SALA4
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLEGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LARC_STAEQ
Sequence: MTKALYLDCHAGIAGDMLLSALVDLGAHPEDIESELKKLPLDQFKLHFQKRVKQGIHAMTLNIDVKESNHHRHVNDIFKMIDDSTLPERVKYRSKKIFEIIGQAEAKIHGMSFEEVHFHEVGAMDSIIDIIGGCIALEQLGINTLYCSAIPTGHGKIHIAHGIYPIPAPATAEILKGIPIAHFDVQSELTTPTGAAFAKGLVSSFGPFPSATIQHIGYGAGSKDFNFPNILRVIQFDSEFEQQDSVQVIECQIDDMTPEALGDFMNNALEQGALDAYYTPIFMKKSRPSTQLTLICKLHDKIYFEQLILQETSSLGVRSTSVNRKILNRAFKILSTQHGTVSIKFGLQNGKIMKMKPEYEDLKKMAKTTNQPFQVIHNEVLQQLYQTYRIGDILQ
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: RLME_CHRVO
Sequence: MARSKSSNNWLQEHVNDQYVHMAQKDGYRARAAYKLLEINDKDKLIRPGTVLADLGSTPGSWSQVAARIVGEKGKVFALDILDMDPVPGVDFIQGDFREEAVLREFEQLLDGRALDLVISDMAPNMSGMSAIDQARSFLLCELALEFARDHLKPGGHFLVKVFQGSDFQPYLKAMRELFDEVVTRKPKASRDRSSEIYLLGKGRR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_NICTO
Sequence: MAKGKDVRVTVILECTSCVRNSVDKVSRGISRYITQKNRHNTPNRLELKKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GUX6_ARATH
Sequence: MVRLKTSLWVLLLALVSIQLNGSFGSESSKVAYVTLLYGDEFLLGVRVLGKSIRDTGSTKDMVALVSDGVSDYSKKLLKADGWKVEKISLLANPNQVHPTRFWGVYTKLKIFNMTDYKKVVYLDADTIVVKNIEDLFKCSKFCANLKHSERLNSGVMVVEPSEALFNDMMRKVKTLSSYTGGDQGFLNSYYPDFPNARVFDPSVTPEVLKTRPVPAMERLSTLYNADVGLYMLANKWMVDDSKLHVIHYTLGPLKPWDWWTAWLVKPVDAWHSIRVKLEETLPGTGGGSNQHDELVVKFLFLLPLCALLFCIYRSIQGREGSLCWSSFSNQIRYLYYKVRSNGTLGYGGVSTMSPSYQPHSGNAQSKVPQHLGAVSVVVCFTAVLLSLGISFAIVPRQIMPWTGLVLVYEWTFTIFFLLFGVFLLFVHQHGKRIAIQSESSSLDDSAKVHQRAGGSCDVTTLYYGLGMAFLAIAAVSLPYILGITALFTRLGLMVGLAIILAAFMTYASEHLAVRWFLKGLEDRRDTTRSNSLCFLC
What is the function of this protein?
Mediates the transfer of glucuronic acid (GlcA) from UDP-GlcA to glycosyl inositol phosphorylceramides (GIPCs) (PubMed:25122154, PubMed:27643972).  The formation of GIPCs sphingolipids is essential for pollen function, plant growth and defense (PubMed:25122154, PubMed:27643972).  Required for global fitness (PubMed:27643972).
What are the official names of this protein?
Inositol phosphorylceramide glucuronosyltransferase 1, Glycogenin-like protein 6, Plant glycogenin-like starch initiation protein 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.