PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_STACT
Sequence: MDDRMVDQSQHEDESSFELSLRPHFLKQYIGQASIKSNLEVFIKAAKLREEPLDHVLLFGPPGLGKTTLSNIIANEMNVNIRTVTGPAIERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFYLDIVIGKGEEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYKESELKDIIIRTAEVLNTEIDEESAVELAKRSRGTPRIANRLLKRVRDFQQVNEDDMIYIETTKRALQLLQVDDYGLDYIDHKMMSCIINQYNGGPVGLDTIAVSIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFEAKNGKRDNFEY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MASZ_VARPS
Sequence: MTARTTTHGLQVATELHRFIEDKVLPASGVASDVFWKGFDAIVHDLAPKNIALLAERDRLQAELDAWHKKNPGPIADMPAYRAFLEKIGYLLPQPKGAKATTANVDSELALQAGPQLVVPILNARYALNAANARWGSLYDALYGTDAIPETGGAEKGKGYNPVRGAKVIEFARNVLDQAAPLENGSHKMATGYSVKDGKLVVALQSSSTGLADPAQFVGYQGDAAAPSSVLLKHNGIHLDIRIDRSTPIGKGDAAGVSDLVLEAALSTILDLEDSVAVVDAADKVVAYSNWLGIVEGTLTEEVAKGGKTFTRGLNPDREYTGADGRPVKLHGRSLMFLRNVGHLMTNPAVLYAGGKEIPEGILDAVVTTTIAMIDLKRKGNSRTGSIYIVKPKMHGPAEVAFASELFGRVEQLLGLPANTVKLGIMDEERRTSVNLKACIAEAAARVAFINTGFLDRTGDEMHTAMHGGPMIRKGDMKSSAWIGAYEKNNVLVGLSCGLRGKAQIGKGMWAMPDLMAAMLEQKIAHPKAGANTAWVPSPTAATLHALHYHQVSVTAVQQELEKIDADAERDNILNALLQVPIAPAANWTEAEKQQEIDNNVQGILGYVVRWIDQGVGCSKVPDIHNVGLMEDRATLRISSQHIANWLLHGVVTKAQVDETFQRMAKVVDEQNAGDPVYQPMAGHFDTSAAYKAAQDLVFKGIEQPSGYTEPLLHAWRLKVKGEV
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAM_ONCVO
Sequence: MSTSTLSDGSLDEGTFAAEDVSGVIEDYFFEGAEKLLEIWFDKNQNGATSLRNIPYSELVSMLDIAQCRILHSKSNECMDSYVLSESSMFISDFRIILKTCGTTRLLHAIERILHIAKIYCNMDNVVSVFYSRKNFMHPEKQPYPHSSFETEVDYLEEHFAGGSAYCIGPQRQDRWFLYTMVTPQAVFPFPEHTLEILMNGLPEDVLSTFSPNVSKDGKDCRMKSAINTILPPDIVVHEELFSPCGYSLNGLIPHSDHYITIHVTPEPDFSYVSFETNQHTLNLCEQMLKVLEIFKPSKFLLTIFTNELSNEGKKMQKNLWDLKICGCRRTNLQFLELPTETLIYVQFERIKSAEQVTCKEVFDR
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: PAX9_LEPED
Sequence: MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPAPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGALEQEAKYGQAPNGLPAVSSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGGTPLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
What is the function of this protein?
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
What are the official names of this protein?
Paired box protein Pax-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: BSK12_ORYSJ
Sequence: MGCCGSSLRVGSHAPEKPPRRARPPPPPPQPHHPRRPSFTLNAHQAAASSSAASAAPAPAFAEFSLAELREATGGFAAANIVSESGEKAPNLVYRGRLQGAGGGGRAIAVKKFGKLAWPDPKQFAEEARGVGKLRHRRMANLIGYCCDGDERLLVAEFMPNDTLAKHLFHWENKAIEWAMRLRVAYNIAEALEYCSNEERPLYHDLNAYRVLFDENGDPRLSCFGLMKNSRDGKSYSTNLAYTPPEYLRNGRVTLESVVFSFGTILIDLLSGKRIPPTLALDMIRSRSIQAIMETNLEGKYSIEEATTLVDLASKCLQYEPRDRPDIKKLVSILQPLQTKSEVPSYVMLGVPKPEEVPKAPPAPQHPLSPMGEACSRMDLTAIHQILVSTHYRDDEGTNELSFQEWTQQMRDMLDARKRGDFAFRDKNFKQAIDCYTQFVDVGTMVSPTVYARRSLCHLMCDQPDAALRDAMQAQCVYPDWPTAFYMQAVALSKLNMQSDSLDMLNEASQLEEKRQKSIKGP
What is the function of this protein?
Probable serine/threonine kinase that functions as a positive regulator of plant immunity.  May be involved in the regulation of pattern-triggered immunity (PTI).  Does not seem to be involved in responses to brassinosteroid (BR) signaling.
What are the official names of this protein?
Serine/threonine-protein kinase BSK1-2, Brassinosteroid-signaling kinase 1-2, OsBSK1-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SMP1_MAGPO
Sequence: MVGFKTLALHLAAVLPALAAPVDKQATQVVPNSYIITLKQGASAASFHNHLSWVGDVHRRSVSKRDTTGVDKVFDLDGFTAYSGSFDAATLQEIKKSDEVAFVEPDQVWDLYTLSTQSGAPWGLGSISHRKPNSTDYVYDPAGLGADHYAYIIDTGLDTEHVEFEGRGTLGYNAYPNSQFIDKIGHGTHVAGTIAGKTYGVAKKASIVSVRVFDTGSVTRQSTTAIVLDGFSWAVKDITAKGRQAKSVISMSLGGGRSEAFNAAVEAAYQANILTVAAAGNSAWDASQYSPASAPNAITVGAIDVDNVMAWFSNYGPVVDVFAPGVAVESAWIGSSHAEHDVLDGTSMATPHVSGLVLYLKSLEGFASAAAVTDRIKALGTNDVVTGLEGTDSPNLIAFNGVTA
What are the official names of this protein?
Subtilisin-like proteinase Mp1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_EHRRG
Sequence: MSRVCDITGQTKSFGNKVSHSNRKTKRTYLVNLHNVTLFSDVLNRKFRFKISSRTLRTIDYKGGFDLYLLETSSRKLSDKAQKIKKMIKKATAENVKVSL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: N7OMT_PAPSO
Sequence: MEVVSQIDQENQAIIWKQIYGFSESLLLKCAVQCEIAETIHNHGTPMSILELAAKLPIDQPVNIDRLYRVMRYLVHQKLFNKEVISTLNGGTVQVTEKYWLAPPAKYLIRGSQQSMVPSVLGIIDEDMFAPWHILKDSLTGECNIFETALGKSISVYMSENPEMNQISNGAMAFDSGLVTSHLVNECKSVFGDEIKTLVDVGGGTGTALRAISKAFPNIKCTLFDLPHVIADSPEIPTITKVSGDMFKSIPSADAIFMKNILHDWNDDECIQILKRCKDVVSAGGKLIMVEMVLDEDSFHPYSKLRLTSDIDMMVNNGGKERTEKEWEKLFDAAGFASCKFTQMSVGFAAQSIIEVY
What is the function of this protein?
Involved in the biosynthesis of benzylisoquinoline alkaloids (PubMed:19500305).  Catalyzes specifically the methylation of norreticuline at position seven to produce norlaudanine (PubMed:19500305).  No activity with norcoclaurine, reticuline, norlaudanosoline, norisoorientaline, scoulerine, salutaridinol, oripavine, salsolinol, codeine or morphine (PubMed:19500305).  Involved in papaverine biosynthesis (PubMed:22725256, PubMed:23738019).
What are the official names of this protein?
Norreticuline-7-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: PELA_EMENI
Sequence: MKTTFLVSLATAALSSTAAAVSVSGSAEGFAKGVTGGGSATAVYPDTIDELVSYLGDDEARVIVLSKTFDFTDSEGTTTETGCAPWGTDAACQVAINQNDWCTNYQPDAPSVSVTYDNAGTLGITVNSDKTLIGEGSAGVIKGKGLRLVSGTSNVIIQNIAITDINPKYVWGGDAITLNDVDMVWIDHVTTARIARQHIVLGTEADNRVTISNSFINGESDYSATCDGYHYWGIYLDGSSDMVTMKGNYIYHTSGRSPKVQGNTLLHAVNNYWHDNSDHAFEIGEGAYVLAEGNVFQNIPTVAEDPIEGELFASPSESANEVCSTYLGRVCELNGFGSSGTFNQADTDFLSKFEGKNIASADSYSSVASSVASSAGNTL
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.
What are the official names of this protein?
Pectin lyase A, PLA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_DESOH
Sequence: MEHPYLFFVKLFEALGFEHFAHTSVHIIYTWVVMALLITLGVLGARNIQIVPTKMQNFLEVLISGIEEFMVSVTGEEGRWFFPLAGTIAIFIAVSNLIGLVPGFFPPTASINTPLACAIVVFVFTHFIGIKYHGPKYIKHFLGPVWWLAPLIFPIEIIGHLARVLSLTFRLFGNMMGHESVLVILFMLGGAFFAPLPIMALGIFVAFVQAFVFFLLSVMYFAGAMEHAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AZOR2_CLOPE
Sequence: MSKVLYVKANIKNEGESRTFKVSDSFVEEYKKNNPEDEIITLDLYKENIDFLRVDDLGKLFGTKDEESKNNSILKYAYQFADADKYIIAAPMWNISFPAILKAYIDYVSVSGITFKYTAEGPVGLLNNKKAVHIVSRGGGYDNSPYEMGDRYLRTILGFFGIKDIETIAIDNLDVMGVNVKEKVEEGIEKAISLAKKF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PYRH_METHJ
Sequence: MPTIVLSLGGSILLPDIDRPNIKPYISVLTRISAKNRLFVVVGGGGTARQYISLARSFEADEAFSDELGIMVTRLNATLLVGALGQAAYPCVVTSHTEALCAAETGKIVVMGGITPGQTTDAVAAVLAERTGADIFINLTAVDGIYSADPRKDPAAKRFETMNPAELLDVVIGQQAVAGVNTVMDIVAVKMVERCGIPLLVMDGRDPALLESTLETGRFVGTLVTRNGKNPFPLKK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOH_CAUVN
Sequence: MAVNSLSVMSPDGGLSRYLTEIRKFPMLSKDEEFMLAQRWKEHQDPQAAHKMVTSHLRLVAKIAMGYRGYGLPIGEVISEGNVGLMQAVKKFEPEKGFRLATYAMWWIRASIQEYILRSWSLVKMGTTAAQKKLFFNLRKAKSQIAAFQEGDLHPDQVSQIATKLGVLDSEVISMNRRLSGPDASLNAPLRADGESEWQDWLADEEQVSQETRVAEDEEKSLRMSLLEEAMVELTDRERHILTERRLKDDPTTLEELAAQYGVSRERVRQIEVRAFEKLQKTMREAAIAKNMVDA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of expression of heat shock genes.
What are the official names of this protein?
RNA polymerase sigma factor RpoH, RNA polymerase sigma-32 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SORC5
Sequence: MAEITREQVVDYLSNLPVIQIAELIKDLENKWGVKAAPAAVAVAAGPAAAAPAEKAPEQTEFDVVLANAGSNKIGVIKAIREITGLGLKEAKDLVEAAPKTVKEQVSKADAEEMKKKLVEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS2_CHLTA
Sequence: MEFPCTLTLKELLESGAHFGHQTSRWNPRMKPFIFEEKNGLYIIDLAKTLAQLKKAVACIQTTIGQEKSILFVGTKKQAKQIIREAAIECGEFFASERWLGGMLTNMATIRNSVKTLNRIELDLEASNSGLTKKELALLAKRHRKLLNNLEGVRHMNSLPGLLIVIDPGYERIAVAEAGKLGIPVMALVDTNCDPTPINHVIPCNDDSMKSIRLIVNVLKDAVIDAKKRLGIGILSPVRPAERPAEEAVEELPLPTGEAQDEASSKEGFLLWADIDNCEALK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MTND_MICAN
Sequence: MAILRLENGTTYTQLADISLELAKLNVTLNYWPIENEATRQLLKQASLTDEEKEIVLTSLDGYFEQLKQEAGYQARDLIVLHPEIANLDTLLAKFERCHTHADDEVRYIIDGEGVFGFVFADGSQGELTIQPQEYINVPAHSEHWFHLTASKRVKAVRYFTSTAGWVPEYTETVIRFPSLTAV
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: ARGB_BACC7
Sequence: MSDYIVVKCGGSMLDQLNDLFFDCIKKLQQKYKVVIVHGGGPEIDAQLKDCNINAEKRDGLRVTPKEVMDVVQMVLCGSTNKKLVMNLQKHNLRAVGCSGCDGNLLQVQPVSEEIGYVGEVRYVETALLKGLINMNYIPVIAPVGINDNEIYNINADTAAAGIAAALSAKELIFITDVDGVLHEGKLVKKTDEFEIVNFIENGVITGGMIPKVQAALASLKMGVQKVSIVNGTKDFTEVTGECIGTTVTRGVSIA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_ECO24
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CALS8
Sequence: MERRQDRIRNFCIIAHIDHGKSTLADRIIELTGALSEREMQDQVLDTMEIERERGITIKAQAVRLNYKAKDGKEYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDATQGIEAQTLANVYLALEHNLEIIPVINKIDLPSARPDEVKKEIEDVIGLDASDAPLISAKQGINIEEVLERIVRDIPPPKGDDTKPLKALIFDSLYDNYKGVLAYVRVFDGVVKPNMTIKMMSTGAQFTVTEVGYFKPGMLIPCEELRAGDVGYIAASIKTVRDTRVGDTITDANNPADEPLPGFRKLNPMVFCGIYPTGDTKYEELKEALEKLQLNDAALFFEPESSAALGFGFRCGFLGLLHMEIVQERLEREYDLNIITTAPSVVYRVTKTNGEVLYIDNPTKLPPPNEIDKMEEPMVKATIMVPNEYVGAIMELCQERRGIFKDMSYIETTRVILTYEMPLMEIVYDFFDALKSRSKGYASFDYEFIGYAESNLVKLDIMIKGEVVDALSFIVHRDKAYQRARKIVEKLKEEIPRHLFEIPIQACIGSKVIARETVKALRKDVLAKCYGGDVTRKKKLLEKQKEGKKRMKQIGEVEIPQEAFMAVLKLEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MSRB_PSEPG
Sequence: MKKIEKTLDEWRSMLDPEQYQVCRLKGTERPFSGKYNSERRDGIYHCICCNLPLFDAQTKFDSGCGWPSFYAPIEDSAMIEIRDTSHGMIRTEVTCARCDAHLGHVFPDGPAPTGLRYCINSVCIDLRPRD
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: Y854_BACLD
Sequence: MMIAIGLFLLAGLAEIAGGYLVWLWLRESKPLWYGLAGGLTLIIYGVIPAFQAFPSFGRVYAAYGGVFIILAVLWGWLVDKKTPDLYDWAGAVICLAGVSVMLWAPRG
What are the official names of this protein?
UPF0060 membrane protein BLi00854/BL03049.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYH_HELPJ
Sequence: MITPKVLSGFKDRLPKDAIQKAQLLAKVSVVFQSFGFVPIETPHLEYAQTLLPDASSDIQKEIYRFKDHGDRDVALRFDLTVPLARFVSLHHQILGMPFKRYAIGNVFRGERAQKGRYREFTQCDFDFIGSESLVCDAEIIQVIIASLKALDLEDFCVSINHRKILNGICEYFGIAQVNEVLRIVDKLEKIGLNGVEEELKKECDLDSNTIKDLLEMVQIKQNDLSHAEFFEKIAYLKDYNENLKKGIQDLERLYQLLGDLQISQNLYKIDFSIARGLGYYTGIVYETTLNDMKSLGSVCSGGRYDHLTKNFSKENLQGVGASIGIDRLIVALSEMQLLDERSTQAKVLIACMHEEYFSYANRLAESLRQSGIFSEVYPEAQKIKKPFSYANHKGHEFVAVIGEEEFKSETLSLKNMHSGMQLNCLSFLKALEIIGENDEDL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNX_SALSV
Sequence: MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPAVDARWQAKFGRSMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIAALRAEGIKIGSCSGYPRAVMERLVPAAAEHGYRPDHWVATDDLAAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPGVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: NRDR_CORJK
Sequence: MLCPSCNSESSRVVDSRSIEMGVSIRRRRECSECQTRFTTIERSVLLVVKRNGVTEEFSREKVIKGVRRACQGRDVSDDALKRLAHEVEQAVRVAHGSQVPANQIGLAILDPLRTLDEVAYLRFASVYKSFNCAEDFEQEIESLRAHRQALAAPPVGDNSEDN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DCSG_STRLA
Sequence: MGILALVTDAVSLPIDYDMPPLLEACRTVGITAEVCDWEDGTVDWSRFEAVVFRSPWTWAERQAEFLAFCERVSHVTRLITPMPLVRWALDKRYLADLAAHGVPVIPTTVVAPGSDALAAVRDFLAARPEAREFVVKPTDGCYSKDVQRYQRSLAEPASRHVARLLANGSHVILQPYVESVDRHGETDLTFFDGVYSHAIHKGAMLMPDGTVHVPTLDFRQARDADEDQRAVAAAALAASVAHLGLDLPLVCGRVDLVRGADGSPMVLEMELCEPSLNLTFSEDGALRFAQALAERLKP
What is the function of this protein?
Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent.  Catalyzes the synthesis of D-cycloserine from O-ureido-D-serine (D-OUS).  It reacts with D-OUS, D-homocysteine and beta-aminooxy-D-alanine.
What are the official names of this protein?
Cycloserine biosynthesis protein DcsG.
Protein: CLS_GEOSW
Sequence: MRNTLRVIIFVLAVAAFLFLTNDYWEGKLLGGLSILISCSVVFIAFVISLENRKPAHTITWLVVLGSFPLIGFFFYLMFGRNYRKQRLFQKKAMLDEQTFLKFQGQREWAIEQMPIGEHQRPLLQLAHRIGKSPVSLATETRVLTNGEETFSTIFEELEKATHHIHLEYYIVRHDEVGQKLKTILIEKAKKGVHVRFLYDAVGSWKLSKTYIQELRDAGVEMIPFSPVRLPFLSNTINFRNHRKIIVIDGTIGFVGGLNIGDEYLGKDKYFGFWRDTHLWIRGEAVRTLQLIFLQDWYYMTGKTLLTPEYLSPELVHYDGQGGVQLIAGGPDQKWEVIKHLYFAMITSAQRSIWIASPYFVPDEDILTALKIAALSGLDVRILAPKRPDKKIVFYASRSYFPELLEAGVKIYEYSKGFLHSKIMIVDGELASIGTANMDMRSFHLNFEVNAFLYHTDSTKKLVADFLEDLKEASPIDYETFQQRPLSIRVVESVSRLLSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_SYNS3
Sequence: MAAAAPASTGSKGVVRQVIGPVLDVEFPAGKLPKILNALRIEGTNTAGEAIGLTAEVQQLLGDHRVRAVAMSGTDGLVRGMEALDTGSPIAVPVGEATLGRIFNVLGEPVDEQGPVNTNVTSPIHREAPKLTELETKPKVFETGIKVIDLLAPYRQGGKIGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINADDLSKSKVALCYGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFVDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGALQERVASTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLNRALASKGIYPAVDPLDSTSTMLQPAVVGDEHYRTARAVQSTLQRYKELQDIIAILGLDELSEDDRQTVDRARKIEKFLSQPFFVAEIFTGMPGKYVKLEDTISGFNQILAGDLDSLPEQSFYLVGNIDEVKAKAEKIAAESK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ECFG_RHOPT
Sequence: MPLTDSLRDDILAAVPSLRAFAISLSGNADRADDLVQETLLRALANIDSFQPGSNLPAWLFTILRNLFRSDYRKRRREVEDADGSYAKTLKSQPGQTAHLEFEEFRAALDKLPQDQREALILVGASGFSYEDAAAICGCAVGTIKSRVNRARSKLSALLYVDGAEDFGPDDTVRAVIGGNG
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).  Regulates expression of hpnP under a variety of stresses, including high temperature, pH stress, and presence of nonionic osmolytes (PubMed:23524612).
What are the official names of this protein?
ECF RNA polymerase sigma factor EcfG, General stress response factor EcfG.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: RUTF_ECOBW
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.