PharMolix/UniProtQA huggingface dataset:
Protein: AMPA_RHIE6
Sequence: MSAKFEISFSKSAKLNSGLAILLKTAEADAAAGAETADPAGVIAKAAKIARFSGKSMAALDIVAPEGAPVERIVVLGLGKAAELTAHDWLKAGGAAASKIKNTDRAAVFLDVPGLTTDARAAADFALGMLLRAYSFDSYKTKKNDDEEKPAKSVKVTIVTADASGAKKAFSDSEAIAGGVNLARDLVNEPPNALGPVEFAARAKELETLGVEVEILTEKEMRRLGMGALLGVAQGSVRPPRLAVMQWKGGRAKDRPIAFIGKGVVFDTGGISIKPAAGMEDMKGDMGGAAAVTGLMHVLASRKAAVNAIGIIGLVENMPDGNAQRPGDIVTSMSGQTIEVINTDAEGRLVLCDALWYCNDRFKPQFMINLATLTGAIVVALGNVHAGLFSNDDQLSARLTAAGLSTNEKLWRMPLGKDYDKLIDSKFADMKNTGGRQAGSITAAHFLKRFVQDTPWAHLDIAGTAMGSPQDEINQSWGSGFGVRLLDELVRAHYEA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRK1_YEAST
Sequence: MNTPQISLYEPGTILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRNFYLLRAMNQNANTQLAGEPSSTTYVPTQKFIPVQSLQSINQPPNMMPVTHVSTTPNLGTFPISINDNNKTEVTAHAGLQVGSHSNLTSPLMKTKSVPLSDEFASLYYKELHPFQKSQTFKSVESFQSPQRKSMPPLSLTPVNNDIFDRVSAINRPNNYVDSETQTIDNMAVPNLKLSPTITSKSLSSTKEIAAPDNINGSKIVRSLSSKLKKVITGESRGNSPIKSRQNTGDSIRSAFGKLRHGFTGNSVNNSRSASFDNNNVNGNGNNTNRRLVSSSTSSFPKFNSDTKRKEESDKNQRLEKRRSMPPSILSDFDQHERNNSRTGSRDYYRSHSPVKKTQASAKTTSKPTLIPDNGNVNINQEKKESIQRRVHNLLKSSDDPVTYKSASGYGKYTDIGTETSNRHSSVRITPITEEKFKKTLKDGVLDIKTKSNGKDKSRPPRPPPKPLHLRTEIQKIRNFSRLQSKKLPIERISSEATETIVDVNVDDLEADFRKRFPSKV
What is the function of this protein?
Protein kinase involved in the regulation of actin cytoskeleton organization and endocytosis (PubMed:9885245, PubMed:10087264, PubMed:11694597, PubMed:11739778).  Phosphorylates PAN1 which disrupts the interaction between PAN1 and END3, and between PAN1 and SLA1 (PubMed:9885245, PubMed:11739778, PubMed:13679512).  Phosphorylates SCD5 (PubMed:12956961, PubMed:13679512).  Preferentially, phosphorylates substrates on threonine residues in a [L/I/V/M]-x-x-[Q/N/T/S]-x-T-G motif (PubMed:9885245, PubMed:11739778, PubMed:12956961, PubMed:13679512).
What are the official names of this protein?
Actin-regulating kinase PRK1, p53-regulating kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein: MAZF7_MYCTU
Sequence: MAEPRRGDLWLVSLGAARAGEPGKHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTPLRPPVAPSEGVAADSVAVCRGVRAVARARLVERLGALKPATMRAIENALTLILGLPTGPERGEAATHSPVRWTGGRDP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli and M. smegmatis inhibits cell growth and colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin MazE7 (PubMed:19016878, PubMed:20011113).  Probably an endoribonuclease (By similarity).
What are the official names of this protein?
Probable endoribonuclease MazF7, Toxin MazF7.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: TRM13_PICST
Sequence: MIKKNRRCAMRRKGSQKYCSEHIIYNESSSIVNTDTKLSEDERVPCPLDGKHTVWKKNLAVHLKKCNAKPVERTEEWFSKDINVKLKNSLGETEDITRSEDKTLDEKDLYSKYIPIIEGINFEPLQYRISEHSGLQQRLNEVLIQKHALQQSSLIGNIKDAKLLSPNNTFVEFGCGKAELSRFVNLCLLDDLKQKVNNEVTLENYGYGFIDRGVNRMKMDKKILKDCLDSPIEITPRIQRTRIDIKDLDLDKFINKLQPSKIVAISKHLCGAATDLTLKSLLNSSLLSDNRDKFGGLLIAMCCRHVCSYDQLLPKSREYLAEKGFKTPDSFRILKKMVSWAVCSKKEHAKNVERLEAEHISQLDYSSRERLGFVARRLIDESRVYALKSMLSGFEVKMFWYVEKDVTLENVCLYVGQEPM
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13, tRNA methylase 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: PSBM_POPAL
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS4_PHEZH
Sequence: MSKRHSAKYKLDRRMGENIWGRPKSPVNSRAYGPGQHGQRRKSKVSDFGLQLRAKQKLKGYYGNITEKQFVRIYTEAARRKGNTSENLIALLESRLDAVVYRAKFVPTPFAARQFVNHGHVLVNGKRVNIPSYRVKPGDVVSVRERSRNMALVLEALQSSERDTPDYITLDAKGMSATFVRAPELAEVPYPVKMEPNLVVEFYAS
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NEK1_HUMAN
Sequence: MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALKHVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQLFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFGSQPIPAKRPASGQNSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEKRVNTGEERRKISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKRQEKERLERINRAREQGWRNVLSAGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKREIYGRGLPERGILPGVRPGFPYGAAGHHHFPDADDIRKTLKRLKAVSKQANANRQKGQLAVERAKQVEEFLQRKREAMQNKARAEGHMVYLARLRQIRLQNFNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFEINVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNGSPRRAWGKSPTDSVLKILGEAELQLQTELLENTTIRSEISPEGEKYKPLITGEKKVQCISHEINPSAIVDSPVETKSPEFSEASPQMSLKLEGNLEEPDDLETEILQEPSGTNKDESLPCTITDVWISEEKETKETQSADRITIQENEVSEDGVSSTVDQLSDIHIEPGTNDSQHSKCDVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQDNLEIDEIEDENIKEGPSDSEDIVFEETDTDLQELQASMEQLLREQPGEEYSEEEESVLKNSDVEPTANGTDVADEDDNPSSESALNEEWHSDNSDGEIASECECDSVFNHLEELRLHLEQEMGFEKFFEVYEKIKAIHEDEDENIEICSKIVQNILGNEHQHLYAKILHLVMADGAYQEDNDE
What is the function of this protein?
Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed:20230784).  Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784).  In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784).  May be implicated in the control of meiosis (By similarity).  Involved in cilium assembly (PubMed:21211617).
What are the official names of this protein?
Serine/threonine-protein kinase Nek1, Never in mitosis A-related kinase 1, NimA-related protein kinase 1, Renal carcinoma antigen NY-REN-55.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=Associated with the pericentriolar material (PubMed:21211617). Localizes to centrosome during interphase and mitosis (By similarity). Translocated from cytoplasm to discrete nuclear foci at sites of DNA damage (PubMed:15604234).
Protein: MYPR_HUMAN
Sequence: MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF
What is the function of this protein?
This is the major myelin protein from the central nervous system.  It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
What are the official names of this protein?
Myelin proteolipid protein, PLP, Lipophilin.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat.
Protein: AFSR_STRCO
Sequence: MDGGPRVPEQRRPGFPAEEEESGALRFGVLGPVRAWRDGETLATGSPQQRALLAALLLREGRTATAGELIDALWGEEPPSQALAAVRTYASRLRKVLDPGVLVSESGGYAVRGLAEGALDLARAQDLASAAEKARSAGDLCHARDLLRRALDLWDGEVLAGVPGPYAQTQRVRLGEWRLQLLETRLDMDLDQGCHAEAVSELTALTAAHPLRERLRELLMLALYRSGRQAEALAVYADTRRLLADELGVDPRPGLQELQQRILQADPALAELSAATAETATATLRPAQLPATVSDFTGRAAFVRELSDVLSAASGESASGRVMAVSALAGIGGVGKTTLAVHVAHRARAAFPDGQLYVDLQGAGARPAEPETVLGSFLRALGTADSAIPDSLEERAALYRSVLDGRRVLVLLDNARDAAQVRPLLPGTDGCAALVTARVRMVDLAGAHLVDLDVMAPEEALALFTKIVGEERVASERQAALDVVGACGFLPLAIRIAASRLAARRTWTVSVLAAKLADERRRLDELQAGDQAVEATFELGYGQLEPAQARAFRLLGLADGPDISLAAAAAVLDLPAQDTEDLLESLVDTSLLESAAPGRYRFHDLVRLYARACAERTERDGNAPSERGAALSRLLDFYLATAAGVYAIERPGDRLVDGLEPTEYPGLTFTEGSAALDWLYTEAAPLLACVRQSAGTARLRRAVDLLWAAKDLTESGANSHQYEATARAMCDATGSAADTRAEGRARTVLSDVLLVSGRIEHAEEEARLAMRLAGSAEDSAAVSWVANNRGLVCLHQRRYAEGKGLFHQAIAGFRATDNRAGEASALSNLSRAQLGMGNVAEAVDIARQGLAVYAELGRTMRLANGHFALGVALTRAGRHEEALGEFAEALDLFGDHRQRLWEGATNFRLAEVHLAAGRPSSAAQHAEQALALGCIGGDRMRGNVLALLGRALSALGQADRARACWREALSLYEQHDAQEVGEVRALLARSVAR
What is the function of this protein?
Global regulatory protein for secondary metabolite formation.
What are the official names of this protein?
Regulatory protein AfsR.
What is the protein family that this protein belongs to?
Belongs to the AfsR/DnrI/RedD regulatory family.
Protein: CT111_CONTE
Sequence: MRCLPVFVILLLLIASTPSDTVPLKTKDDMPQASFHGNARRTLQMLSKKQCCWYFDISCCITV
What are the official names of this protein?
Conotoxin Tx-D0111.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CXCL5_HUMAN
Sequence: MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
What is the function of this protein?
Involved in neutrophil activation.  In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
What are the official names of this protein?
C-X-C motif chemokine 5, ENA-78(1-78), Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, Small-inducible cytokine B5.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_HALHL
Sequence: MAKASSRGGGKKKVKRTVSDGVAHINATFNNTLITITDRQGNALSWASAGGSGFKGSRKSTPFAAQVASETAARAAQDYGLKNVEVRVKGPGPGRESAVRALNAVGYRITNISDVSPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HEM3_XANOR
Sequence: MTTLRIATRKSPLALWQSEHVAAALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGDKGLFLKELELAMLRGDADCAVHSFKDVPMELDDPFVLPAILERGDPADALVSNLYASLQALPLGARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLDERISARLDAPEWLPAPAQGAVAVECRGDDARIHSLLAVLDAGRTRACVEAERAMNRALHGSCHVPVAALARWEGEGLFLQGMVGSASDGRLIHADAHGSADDTQDLGRRVAQGLFDKGAAQLLAAL
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SIGK_MYCBO
Sequence: MTGPPRLSSDLDALLRRVAGHDQAAFAEFYDHTKSRVYGLVMRVLRDTGYSEETTQEIYLEVWRNASEFDSAKGSALAWLLTMAHRRAVDRVRCEQAGNQREVRYGAANVDPASDVVADLAIAGDERRRVTECLKALTDTQRQCIELAYYGGLTYVEVSRRLAANLSTIKSRMRDALRSLRNCLDVS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigK, ECF sigma factor SigK, Alternative RNA polymerase sigma factor SigK, RNA polymerase sigma-K factor, Sigma-K factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: MURB_RICPU
Sequence: MLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNIIIRDGGIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEAIGFKYRSNNLPKNLIILKVVFKINKGDSENILLRMNEINNARSSTQPIKERTGGSTFANPEGHKSWELIDKAGLRGYRIGGASMSELHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_FRATF
Sequence: MKNKNSEQNTHYTIGEQDIHYFHEGKHIYAYEFMGAHKACEEGIEGIRFTTWAPNAKSICVIGDFNYWQVEDKNYMEPITDAGLWSVFIPNAKNGDKYKFVVTNKDTSHYVYKSDPYAFFSELRPNTASIITTETQYTWSDDKWLEKRAKTNYYDNPMNVYELHLASWKTKNGKFLTYDELSETLPQYIKEMGYTHVEFMPLHEHPLDASWGYQPTGFYSVNSRHGDIIGLKRLVDKLHNNDIGVILDWVPGHFCKDQHGLIYFDGSPCYEYQEPTKAINKGWETHNFDLGRNEVKCFLISNAMYWINEFHIDGLRVDAVSNILYLNYDREDGQWIPNIYGGHENLEGIAFLKELNGVLKHTCKGVITIAEESSSWPDISTPVEKGGLGFDFKWNMGWMNDTLRYISLDPVYRKYHHNLITFSMVYHYSEKFILSISHDEVVHGKKSLINKMWGDLWNKYAGLRLYMSYMIGHPGKKLIFMGSEFVQFVEWREYEQLQWQVVDQYESHKQTLHFFKKLNDFYHNETALWQCDYDHHGFRWIDANNSQQSILSFIRSSKDNKQKLIFICNFTPVTYYDYHLGVPDAGSYKEVFNSDNLEFGGSGQVMATEIFSSPQSSHGFEQRITIKIPPMATLVLKLIK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: DCUP_FLAPJ
Sequence: MIKNDLFLKALKGETVQRPPVWMMRQAGRYLPEFIALRDKYDFFTRCQTPELAAEITVQPIRRIAPDAAILFSDILVVPQAMGIEVLMKENVGPFLPNPIRTIQDVERVIVPDVHQTLGYVFDAIKLTKQMLNDEVPLIGFAGSPWTIMCYAVEGQGSKSFDKAKGFCFSHPEAAHVLLQKITDTTIAYLTEKVKAGCNAIQIFDSWGGMLSPVDYQEFSWKYINQIIEALADITPVIVFGKGCWFALGEMGKSKASALGVDWTCSPRHARYLSGGNITLQGNFDPSRLLSPIPVIKKMVHEMIDEFGKDKYIVNLGHGILPNIPVDHAKAFVDAVKEYNQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_ROSS1
Sequence: MARKALIVKAQRPQKYKVRAYNRCKICGRPRAYMRKFGMCRICFREHALRGLIPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PIF1_RAT
Sequence: MPSSTEVATDECDDTELRCRVAVEELSPGGQPRKRQALRAAELSLGRNERRELMLRLQAPGPEGRPRCFPLRAVRLFTRFAAVGRSTLRLPADGVPRAGSVQLLLSDCPPERLRRFLRTLRLKLAVAPGPGPASARAQLLGPRPRDFVTISPVQPEELRRAAATKAPDSALEKRPMESQPSMEAPRWPLPVKKLRMPSSKPKLSEEQAAVLRMVLKGQSIFFTGSAGTGKSYLLKHILGSLPPTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVALAHRPGVRQGWLNCQRLVIDEISMVEADFFDKLEAVARAVRQQKKPFGGIQLIICGDFLQLPPVTKGSQHPRFCFQAKSWRKCVPVTLELTEVWRQADQTFISLLKAVRLGRCSDEVTRQLRATAAHKVGRDGIIATRLCTHQDDVALTNEKRLKELPGDVHSFEAIDSDPELSRTLDAQCPVGRVLQLKLGAQVMLVKNLAVSRGLVNGARGVVVGFESEGRGLPRVRFLCGITEVIRTDRWTVQVTGGQYLSRQQLPLQLAWAMSIHKSQGMSLDCVEISLGRVFASGQAYVALSRARSLQGLRVLDFDPTVVRCDSRVLQFYATLRQGRGLSLESQDDEEASSDLENMDPNL
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.  Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids.  Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs.  Involved in the maintenance of telomeric DNA.  Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase.  Reduces the processivity of telomerase by displacing active telomerase from DNA ends.  Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction.  Possesses an intrinsic strand annealing activity.
What are the official names of this protein?
ATP-dependent DNA helicase PIF1, DNA repair and recombination helicase PIF1, PIF1/RRM3 DNA helicase-like protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: SYP_BACLD
Sequence: MRQSRTLIPTLREVPADAEAKSHQLLLRAGFIRQNTSGVYSYMPLANKVIHKIQSIVREEMEKINAVEMLMPALQQAETWQESGRWYTYGPELMRLKDRHGREFALGATHEEVITSIVRDEVKSYKRLPLTLYQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHSSAESLDETYNDMYQAYTNVFTRCGLNFRPVIADSGAMGGKDTHEFMALSDVGEDTIAYSDQSSYAANIEMAEVKETDAGEQAEMKELQEVHTPSVKTIEEVAAFLGISPSDCIKSMLMKADGRFVLVLTRGDHEVNDVKVKNLLQAEIIEFASAEEVAEITGTEPGFVGPVGLDREIEIFADFAVKAMANAAAGANKTDYHYQNVNISRDAHNVTFADLRFIQEGDPSPDGKGTIRFAKGIEVGQVFKLGTRYSEAMDATYLDENGRAQPMLMGCYGIGISRTLSAIVEQHHDDKGLIWPLEVTPYDLHILALNMKNDAQVQLAEKLYEEFKANGYDVLFDDRAERAGVKFADSDLIGLPIRITVGKRADEGVVEVKIRKTGESFEIAADELFDFIEKQVKSLSSHS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CHLFF
Sequence: MSSKEIVSNRKALRNYEVLDTVDAGVVLTGTEIKSLRDHGGNLGDAYVTISKGEAWLLNASIAPYRFGNIYNHEERRKRKLLLHRYEIQKLESKVSQKGITIIPLGMFLSRGYVKIRLGCCRGKKAHDKRQTIIAREKQREVESAMKRYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MURD_CAUSK
Sequence: MIPVRGFEGKTVAVFGLGRTGLTAARALIAGGAKVALWDEKPESRQAAVAEGLNVVDLTTSDWSDYAALMLSPGVPLTHPKPHWTVGKAKAAGVEVLGDIELFARTVNAAPEHKKPKIIAITGTNGKSTTTALIGHLCRQAGRDTRVGGNIGEGVLGLEDMHGGAVYVLELSSYQLDLTSSLKPDAVVLLNISPDHLDRHGGMDGYIAAKRRIFLNQGKGDTAIIGVDDPWCQQICTEITAANRRTIWPISAGKAMGRGVYALQGVLYDATGERVTEMADLLRARSLPGRHNWQNAAAAYAAAKAIGIPAHQAVDGLMSFPGLAHRMETVGKLGKVRFVNDSKATNADAARQAMSSYPKFYWIAGGVPKAGGIDDLVDLFPRVAGAYLIGQAAEDFGKTLEGKAPARQCGDIETAVAAAYADAVASGEEAVVLLSPACASFDQFADFEQRGEAFRAAVNGLGKPAAKRA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMB_PHOLL
Sequence: MSEIIYGIHAVKALLERDPQRFIEVYVLKGREDRRLTPLIHALESIGMTIQLANRQWLDNQTEGAVHQGIIAKVKPGRQYQENDLPDLLAQVETPFLLVLDGVTDPHNLGACLRSADAAGVHAVIIPRDRSAQLNATAKKVACGAAESVPLIRVTNLARTLRLLQEYNIWVVGTAGEADHTLYQSKLTGPMALVMGAEGEGMRRLTREHCDELISIPMVGSVSSLNVSVATGVCLFEAVRQRSS
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.