PharMolix/UniProtQA huggingface dataset:
Protein: GCST_SHISS
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVLEGIGETAIVQIRNREMSVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PRMA_ALKEH
Sequence: MPHTQITLDCAQSQVPRVEALLEALGALAITLSEPDDEEILEPGPGEQRLWSHLRLTALFDAATVDPLRLQARVAEVLGAPPRGWRVERLVDRAWERAWMDDFHPMRFGDRLWVVPWGQTPPAAEAVNLRLDPGLAFGTGTHPTTALCLRWLDGLPLQADTRLVDYGCGSGILAVAGCLLGAGHCTAVDNDPQARQATADNARRNGVGERIRVQGPGPLPRAGADVLVANILARVLVAMAGELSPSVRPGGRIALSGILRGQVDQVRACYSSWFEMERPEYQGDWALLAGTRRG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_HAEI8
Sequence: MSMQDPIADMLTRIRNGQAANKVAINMPSSKLKVAIANVLAAEGYIESVKVLEGAKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ZN679_HUMAN
Sequence: MAKRPGSPGSREMGLLTFRDVVIEFSLEEWQCLDHAQQNLYRDVMLENYRNLVSLGIAVSKPDLITCLEQNKEPWNIKRNEMVTKHPVMCSHFTQDLPPELGIKDSLQKVIPRRYGKSGHDNLQVKTCKSMGECEVQKGGCNEVNQCLSTTQNKIFQTHKCVKVFGKFSNSNRHKTRHTGKKHFKCKKYGKSFCMVSQLHQHQIIHTRENSYQCEECGKPFNCSSTLSKHKRIHTGEKPYRCEECGKAFTWSSTLTKHRRIHTGEKPYTCEECGQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKRIHTGEKPYTCEECGKAFNCSSTLKKHKIIHTGEKPYKCKECGKAFAFSSTLNTHKRIHTGEEPYKCEECDKAFKWSSSLANHKSMHTGEKPYKCE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 679.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYK_PSEP1
Sequence: MSDLKTESQDLQQEENALIALRKEKLAAERAKGNAFPNDFRRDSYCNDLQKQYADKTKEELEAAAIPVKVAGRIMLNRGSFMVIQDMTGRIQVYVNRKTLPEETLAAVKTWDLGDIISAEGTLARSGKGDLYVEMTNVRLLTKSLRPLPDKHHGLTDTEQRYRQRYVDLMVNEETRHTFRVRSQVISHIRKFLIERDFLEVETPMLQTIPGGAAAKPFETHHNALDMAMFLRIAPELYLKRLVVGGFEKVFEINRNFRNEGVSTRHNPEFTMLEFYQAYADYRDNMDLTEELFRELAQLVLGSTDVPYGDKVFHFGEPFVRLSVFDSILKYNPELTAADLQDVDRAREIAKKAGAKVLGHEGLGKLQVMIFEELVEHKLEQPHFITEYPFEVSPLARRNDDNPAVTDRFELFIGGREIANAYSELNDAEDQAERFLAQVAEKDAGDDEAMHYDADFVRALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFPHMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BORPA
Sequence: MGVTRIGLLGGSFDPVHVAHIALADTARQFLGLDQVQLIPAANPWQRQPLKASAPHRLRMLELAIAGHPALAINPVEIERGGATYTADTVRALPGGPQYFWLLGTDQLQNFCTWRDWQDIAARIELAVATRPGASIAPPAELATWLAAHRRQLHELPFAPMAVSASDIRQRLAADAATDGLLPEPVAAYIATHHLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ST217_CAEEL
Sequence: MLLFQKTLSRVAAPISVAANLILILLIIFKSPAQMGNYKYLLIGLSIFEMSYAVLDVVSETTVLSIKKSFVVVVPYKDRSFGQETAMDINLIYCGFFGFSMGMFVVIFAYRSFLTTGNTILRKFEGFKIISWFAYPLFYAIVWILVAWGPLASFPEMDIVVRPFLLDELNMTVDEVAYTGRLFYSTIDNSLRYSAILTGVLQWVLTASSLFLVIFFGLRCYFHYGKLVQLTDVQSIRLRQLQNQLFLALVCQATVPLILMHIPVTILYTCCVLNIVFNPFSVATTIALFPAIDPLPTIFIVKNYRVALFEFVCPSCLCWSETLKHMGSNRITSYRSNTVNALSM
What is the function of this protein?
Probable G-protein coupled receptor.
What are the official names of this protein?
G-protein coupled receptor str-217.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein str family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPIA_RHIL3
Sequence: MDAREMKIKAAEAALAHVESGMRLGIGTGSTAEEFVRLLAEKVAGGFRVEGVPTSERTARLCVELGVPLKSLDELPALDLTIDGADEVDQALRLIKGGGGALLREKIVAAASERMIVIADESKLVETLGAFALPIEVNPFGLVSTRIAIEKVAARLGLSGELDLRQSGDGEFTTDGGHHIIDASFGRIPDAEALSSELNSIPGVVEHGLFINMAALAIIAGPAGARTLQANR
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: AOX_MAGO7
Sequence: MLVHQVNTKLCSAKQFTHLAKVVTPALSYQASSVYSANLPRLAASPRLFSTTSSAQLRDFFPVKETEHIRQTPPTWPHHGLTEKEMVDVVPGHRKPRTLGDKFAWSLVRISRWGMDKVSGLSSEQQQINKGSPTTSIVAAKPLTEAQWLSRFIFLESIAAVPGMVAGMLRHLHSLRRLKRDNGWIETLLEEAYNERMHLLTFLKMCEPGWLMKILIIGAQGVYFNAMFVAYLISPKICHRFVGYLEEEAVHTYTRSIEELERGDLPKWSDPKFQVPEIAVSYWGMPEGHRTMRDLLLYIRADEANHRGVHHTLGNLNQVEDPNPFVSDYKGDKPRPVAASRPEGFEREEVIGKEVIGKEVIEKDVIGKEVLGKQVSV
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial, AOXMg, MgAOX.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: CYB_SPEFU
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGMYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLVLTLMALVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHLSKQRSMMFRPLSQCVFWILVADLFTLTWIGGQPVEHPFIIIGQLASILYFAIILLILPTVSMIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNHE1_STAAS
Sequence: MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E1, Mnh complex subunit E1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VATA_CLOPE
Sequence: MKTGKIIKVSGPLVVAEGMDEANVYDVVKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVITTGEPLSVELGPGLIESMFDGIQRPLDAFMKAANSAFLSKGVEVKSLNREKKWPFVPTAKVGDKVSAGDVIGTVQETAVVLHRIMVPFGVEGTIKEIKAGDFNVEEVIAVVETEKGDKNLTLMQKWPVRKGRPYARKLNPVEPMTTGQRVIDTFFPVAKGGAAAVPGPFGAGKTVVQHQVAKWGDTEIVVYVGCGERGNEMTDVLNEFPELKDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVVALGKDGREGAVTAIGAVSPPGGDISEPVTQSTLRIVKVFWGLDAQLAYKRHFPSINWLTSYSLYLEKMGEWMDAHVADDWSALRTEAMALLQEEANLEEIVRLVGMDALSEGDRLKLEVAKSIREDYLQQNAFHENDTYTSLNKQYKMLNLILSFKHEAEKALEAGVYLDKVLKLPVRDRIARSKYISEEEISKMDDILVELKSEMNKLISEGGVLNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CHEB1_CARHZ
Sequence: MSRYKLFIVDDSALIRLRLKTSLALWPEIQIVGEAENGQEALKKIPLVKPDVVTLDLEMPVLDGLSTLKELNKVYPVPVIMLSSLTTHGAKATIEALENGAVDFVPKDGDWNKVVSELKEKIKIAVLAKKRPKPFTGGTLNPKNVILGKNGRQLVVIGASTGGPPALREIIPKLPQTFPVPIVIIQHITRGFSKPLADQLARVSRLKVKEAEKDEQLLPGTVYVAPAGYTFKIDKQGGSLTAKIIEPVEYLPAHFYPSVDEAMLSAAEVTGSKTIGVLLTGMGKDGALGMKAIKERGGYTIAQDEETSVVYGMPKAAIDIGGVSRVLPLSAIAEEIAANI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL15_SHEEP
Sequence: MRILKPYLRSTSIQCYLCLLLNSHFLTEAGIHVFILGCISAGLPKTEANWQSVIHDLKTIEHLIQSMHMDATLYTESDAHPNCKVTALQCFLLELRVILHESKNAAIYEIIENLTMLADRNLSSIENKTELGCKECEELEKKSIKEFLKSFVHIVQMFINTS
What is the function of this protein?
Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems.  Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines.  In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection.  Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits.  Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity).  In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity).
What are the official names of this protein?
Interleukin-15, IL-15.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FSQA_ASPFU
Sequence: MMDDKHGRYGACDRCRGQKLRCVGAGKPIPNSSSRLLRNEIPCDRCRRAKVECYSVRPAPRRAASNVKEQMIATQAASERSSSLAYHTSGPVVSPPNSLVTAASKPHPNSLSFNHPRSDAVAAPGGLQTRRQSRDTDSLGDMPSMPHEWMAYLHDHKMDDRQGLGMETPPLIESDLNLSRDPAMDSMHEHNMMMELIHQDHQEEWNSGPPELEAYPDPIVPPNPAPLKARKLTSPDCDDYPYGHTRRSSHTPTQPPEPAGRSCIQELAQFNEMLLRDKCSLEDTSARRGYKDSWLSIGRTLHHCQQFFSILKRIKYSRPDSQLSADRARSQWSSLPEGTSLADGAPTDSPQARRSLARGATPCSSSLARSSSTSSAASTSYLGLSTLLSILFCYTYILQAYEDILTSILHAVTRPTPTIPPTLSGLRIDGFQLDGHHTLQLECLLHVSYNLLEKIENILFGSAGPEELSNPVKYGILGDKLSAGLIDALFEHNETNGLLHCQGKREVAAKRLIREIQAALKQLDL
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of the isoquinoline alkaloids fumisoquin A, fumisoquin B and fumisoquin C; as well as small amounts of fumipyrrole as a shunt metabolite (PubMed:25582336, PubMed:27065235).  The products of the cluster lead to a brown coloration and are important for growth and conidiation (PubMed:25582336).
What are the official names of this protein?
C6 finger transcription factor fsqA, Fumipyrrole biosynthesis protein R, Fumisoquins biosynthesis protein A.
What are the subcellular locations of this protein?
Nucleus.
Protein: YR570_MIMIV
Sequence: MNDQNSNQFIIYDSNNGFVITPKLTDNIISKLIDFIDQSRNSYREYYGVNCFLWKLDLVNNAIISDSAVEFIIDNDIFSQLSHIASYLFNHYYRLKGTFYCRTENIIEYIYMDGLTNLLTHYVLIDTIDSMCNDDSNDNEKLLSESKEKLNVFIKSTKGFTSDSESVEDIEKNNQSNITCKKIYYVNKIYNNPIINIGDSGKYSELKTKVNDIENDLRTLSSNTNLLWKISALMSMIIVGTVCYLRK
What are the official names of this protein?
Uncharacterized protein R570.
Protein: FB234_ARATH
Sequence: MTTMSDLSPDLVGEILTRVPMTSLISVRCTCKMWNALSKEGIFFKAARKQFMGFTMMDSRVCSMKFDLQGIRNNEHDFVDPCIKQIAKLDQIEVSKVLQCDGLLLCVGKDNSRLLVWNPYLGQTRFIKPRKRFNKLEWYALGYDNNHNYKILMNYDTGHLFGYEIYDFSSDSWRVLDVSPDCHIPFHQQSVSLNGNTYFLAQEKIIVEGEEEEVVDEIEKFLLCFDFTTERFGPRLPLPFHSDVLETVAISCVRDDQLAVLYQRFETWEIWVTTKIDPTAVSWSMFLSVDMEPPTGCQFDDEAGSFFIDEENKVAVFFNSDLFNPRVENRNRRYPTAYIIGQDGYFKSATLREAPDLVKPDPYVYCCPLVWSSYAPSLVQL
What are the official names of this protein?
Putative F-box protein At4g17200.
Protein: GCS1_ARATH
Sequence: MTGASRRSARGRIKSSSLSPGSDEGSAYPPSIRRGKGKELVSIGAFKTNLKILVGLIILGIIVIYFVINRLVRHGLLFDESQKPRVITPFPAPKVMDLSMFQGEHKESLYWGTYRPHVYFGVRARTPLSLVAGLMWLGVKDEMYVMRHFCENSDDLSTFGWREHNGRDYGRQELVENDMVIETSFVKSKGDGLGYGGDWAVRIDVKNKGLNDDVKRSAHLFFYLADEGGNVLNLGQDGLDFQGSSLLVSGSREDVGDWQIHLKSQNQLETHYSGFKTPHIYNLSDLVQQNLALQARKFGRLQLSDTSEDSSNIYIFQISGRLPFTIDIPFISGIKGESSNVEKRLTSLTGLPLSDLLKKKHQEFDAKFNECFKLSEKHDSETLGVGRTAIANMLGGIGYFYGQSKIYVPKSTQPGSRDNFLLYWPAELYTAVPSRPFFPRGFLWDEGFHQLLIWRWDIRITLDIVGHWLDLLNIDGWIPREQILGAEALSKVPEEFVVQYPSNGNPPTLFLVIRDLIDAIRMEKFVASEKDEVLSFLERASVRLDAWFQWFNTSQKGKEIGSYFWHGRDNTTTQELNPKTLSSGLDDYPRASHPSEDERHVDLRCWMYLAADCMHSITELLGKEDKLSKENYNSTVKLLSNFNLLNQMHYDSDYGAYFDFGNHTEKVKLIWKEVIQENGQLSRQLVRKTFGKPKLKLVPHLGYVSFFPFMSRIIPPDSPILEKQLDLISNRSILWSDYGLVSLAKTSSMYMKRNTEHDAPYWRGPIWMNMNYMILSSLYHYSIVDGPYREKSKAIYTELRSNLIRNVVRNYYETGYIWEQYDQVKGTGKGTRLFTGWSALTLLIMSEDYPIF
What is the function of this protein?
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.  Required for the accumulation of seed storage proteins, the formation of protein bodies, cell differentiation, cellulose biosynthesis and organization (in cell walls), cell shape determination and organization (e. g.  epidermal cells), and embryo development.  Involved in root development.
What are the official names of this protein?
Mannosyl-oligosaccharide glucosidase GCS1, Alpha-glucosidase 1, Glucosidase 1, Protein KNOPF, Protein MUNCHKIN.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 63 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: SERK2_ORYSJ
Sequence: MAEARLLRRRRLCLAVPFVWVVAVAVSRVGANTEGDALYSLRQSLKDANNVLQSWDPTLVNPCTWFHVTCNPDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQVLDLSNNNLSGEVPSTGSFSLFTPISFANNKDLCGPGTTKPCPGAPPFSPPPPFNPPTPTVSQGDSKTGAIAGGVAAAAALLFAVPAIGFAWWRRRKPEEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRLADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESLIQVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEVVRQEAELAPRHNDWIVDSTYNLRAMELSGPR
What is the function of this protein?
LRR receptor kinase involved in positive regulation of somatic embryogenesis and defense response against the rice blast fungus pathogen Magnaporthe oryzae (PubMed:15968510).  Involved in the positive regulation of receptor kinase-mediated immunity.  Required for immunity mediated by the LRR receptor kinases XA21 and XA26/XA3 which recognize effectors from the bacterial pathogen Xanthomonas oryzae pv.  oryzae (Xoo).  Required for the immune response mediated by the LRR receptor kinase FLS2 which recognizes specifically the bacterial flagellin (flg22) effector.  Kinase activity and direct interaction with the immune receptors is critical for their function (PubMed:24482436).  Involved in the regulation of plant growth through the brassinosteroid (BR) signaling pathway (PubMed:19754838, PubMed:24482436).
What are the official names of this protein?
LRR receptor kinase SERK2, BRI1-associated receptor kinase 1 homolog 2, OsBAK1-2, Somatic embryogenesis receptor kinase 2, OsSERK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CAC1S_HUMAN
Sequence: MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEIEMEEMESPVFLEDFPQDPRTNPLARANTNNANANVAYGNSNHSNSHVFSSVHYEREFPEETETPATRGRALGQPCRVLGPHSKPCVEMLKGLLTQRAMPRGQAPPAPCQCPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKGREAPEGMASSLGCLNLGSSLGSLDQHQGSQETLIPPRL
What is the function of this protein?
Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle.  Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca(2+) release from the sarcplasmic reticulum and ultimately results in muscle contraction.  Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1S subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein.
Protein: TILS_STRP4
Sequence: MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_NITOC
Sequence: MENNAYPTLPLKNTVLFPHLVLPLSVGRAGSIAAVEAALSSEDKLIAVFPQKDPRTDEPAADDLFRFGTVGIIKKMVRSEDTVQILVQGIERVEQLEMVQKQPYLSLKIATLSEPSDTGTEIEALHRTVIELAGKMIELVQPQIQVGIHHIISDVEKPLHQIYLLTSILSLDFDKEKELLAAATQVEALQLMHRYLNHEVQVLEVRQKITSTAQTEIDKKQREYVLRQQLEAIQEELGETNPEQAEIKELRQRMEETELPELVRKEVEKEITRLERMPSAAPDYQLTRGYVELALELPWNKTTEDRLDLKRAREILDEDHFDLEDVKERIIEHLAVMKLNPEAKSPILCFVGPPGVGKTSVGQSMARALGRKFERMSLGGLHDESELRGHRRTYIGAMPGRIIRAIRRTGYQNPLLMLDEIDKLGRDFRGDPAAALLEILDPAQNAEFHDNYLDLPFDLSKIFFVTTANTLDTIPRPLLDRMEILRLPGYSDEEKQHIARRYLIGRQIREAGLSEIQLSIPDETLSYLIRRYTREAGVRELERMLGRIARKVATQVATGQTQPVTVTPQDLVELLGPERFFAEEMRQQLAPGVAAGLAWTEAGGDVLYVEAALLPEGKGMTLTGQLGSIMQESAKAAQSYLWSRAEELNIDQKTIRESGVHIHVPAGAIPKDGPSAGVTMASALTSAYAHQPVRSDTAMTGEITLSGLVLPVGGIKEKVLAAHRSGIQRIILPKENEKDLREIPEHVRQSIQFILARRIEEVLAEAIPDLNR
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CUPMC
Sequence: MQLLAIGINHTTAPVSLRERVAFPLEQIKPALGALRTHLSGRNGTEAAILSTCNRTEIYCATDVLKPGEEGFEHTLRWLAQHHNVPASELAPHLYALPQSEAVRHAFRVASGLDSMVLGETQILGQLKDAVRTAGEAGALGTYLNQLFQRTFAVAKEVRGQTEIGAHSVSMAAAAVRLAQRIFESVSTQRVLFIGAGEMIELCATHFAAQTPRQIVVANRTVERGEKLAEQLSEQGLTTQAIRLQDLGDRLHEFDIVVSCTASSLPIIGLGAVERAVKRRKHRPIMMVDLAVPRDVEPEVARLDDVFLYTVDDLGAVVREGNALRQAAVAQAEAIIDSRVLNFMHWLETRSVVPVIRELQSQGEAIRQAEVERARRMLARGDDPAAVLEALSGALTRKFLHGPTHALNHTQGEDREALLRLVPGLFRHSSHSER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: YQGF_STRPI
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDRVKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVAAERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.