PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_BRUAB
Sequence: MTMENKPAGQNGLTYAQAGVDIDAGNLMVEKIKPLVRSTRRPGADGEIGGFGGLFDLKAAGFKDPVLVAANDGVGTKLKIAIDADIHDTVGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLSPDQGVAIVSGIAEGCRQAGCALIGGETAEMPGMYRDGDYDLAGFAVGAAERDRLLPRGDIAEGDIILGLASSGVHSNGFSLVRRIVELSGLGWKSQAPFQPGATLGEALLTPTRIYVKPLLAAIRACDGIKALAHITGGGFPDNIPRVLPKGLAAEIDLPAIAVPPVFSWLAKTGNVEPNEMLRTFNCGIGMIAVVNPAKVDEVIAALAAEGEKVVTLGRMTRREKDGVIYKGQLAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_CALMQ
Sequence: MATDAAELFKEALSLFPGGVNSPVRAMKHLPTPLIVKRAEGAFLYTIDGVKLIDYCMGFGPLILGHRHPTVLEAVRRSLEDGWLYGALTRNEVELAKEINSSIRSVEMIRFVNTGTEAVMNAVRLARGFTGRRYIVKFEGNYHGAFDYVLVKAGSGAATWGVPTSAGILEDAVKYTLVVPYNDVEALERVFREHGSEIALLLVEPIAGNYGLIIPDLEFIKATRELTERYGALLLFDEVITGFRVGLNGAQGLFGIKPDLTTLGKIIGGGFPIGAFGGRRDVMSMITPQGPVYNAGTFNAHPVSVAAGLATIRVIKSGGVYEVANEAAERITEAILDSASRSGFDIVVKRIASMFQFYFKKGDVKTPADVRASDEKLYLTFHREALSRGVYFTPSQYEVNFTSAAHSRDVVDETIRVIEEVFKALKTKAH
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDZ12_CAEEL
Sequence: MSLSSLDAVLSLIATSSTLDQDSAKVPQCQVCKRKFANQKTLRTHMKHITCRPGRSNVVNHKFRCENCEKQFTNKPNLKRHQITHSGSKSKKCSTCQRTFFREDQLQRHLHNHLKERSHFDCPVLNCSMQFVFYEGVENHLVNHHHFSYSESAPCGKCHKLFGSPRHLLVHYHFDHKEALRSSAPAPTSSARLSPITVSTSGSPRAQLAISPQEKPPQKLSINLGTSPMIEEFCEQNSATLPNTDQQLSPTLSPNEPRFRNLITSEPTPSFECKHCTIKFHDATMSIMHNALHAPGSPFKCAICGAECGNKIVFTMHIITASHDFGGIGT
What is the function of this protein?
Together with ehn-3, may play a role in gonadogenesis.
What are the official names of this protein?
Zinc finger protein sdz-12, Skn-1-dependent zygotic transcript 12 protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: IF2P_SACS2
Sequence: MKISNSERRLRQPIVVVLGHVDHGKTTLLDKIRGTTVVKKEPGEMTQEVGASFVPSYIIEKLAEPLKKVIPIKLQIPGLLFIDTPGHEYFSNLRRRGGSVADIAILVVDITEGLQKQSIESIQILRERKVPFLIAANKIDKIPGWKSNNDIPFLASIEKQRNDVKVYLDNLVYNLVSQLANLGFSSERYDRIKDFTKTVAIVPVSAKTGEGVADLLALLAGLTQRYLETRLKFAEGPAKGVILEVKEDPGLGHTIDVIIYDGVLKKNDTIILGGINGIIITKVRGIFVPRPLQDMKLSKYDLTPIDEVYAAAGVKISAPNLEEALAGSPIYVVEDESKVERYKQQIEEEIKEVRLYSDIDGIILKADSLGTLEALVSALQREGIPIRLADIGPISKRDVIEASIVAQRSKEYGIIAAFRVKLLQGIDTSGIKILYNEIIYQLIEDIKKHINDVREAEKRRTFDTLILPGKIKILPGYVFRRSDPVVVGIEVIGGIIRPKYPLIKEDGRRVGEVLQIQDNKKSLERATKGMEVAISIKGNIMIGRHVNEGDVLYTDVPKEDLEILVNKYPSSITDDMREVIKEIIRIKRKEDPLYGLGLQI
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: STK3_MOUSE
Sequence: MEQPPASKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIKNAKPVSILRDLIAEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSSESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEEEEEEEEEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCDQSMREPGPMSNSVFPDNWRVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELHQRYSAKRQPILDAMDAKKRRQQNF
What is the function of this protein?
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.  Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.  Phosphorylates NKX2-1.  Phosphorylates NEK2 and plays a role in centrosome disjunction by regulating the localization of NEK2 to centrosomes, and its ability to phosphorylate CROCC and CEP250.  In conjunction with SAV1, activates the transcriptional activity of ESR1 through the modulation of its phosphorylation.  Positively regulates RAF1 activation via suppression of the inhibitory phosphorylation of RAF1 on 'Ser-259'.  Phosphorylates MOBKL1A and RASSF2.  Phosphorylates MOBKL1B on 'Thr-74'.  Acts cooperatively with MOBKL1B to activate STK38 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The caspase-cleaved form cycles between nucleus and cytoplasm (By similarity). Phosphorylation at Thr- 117 leads to inhibition of nuclear translocation (By similarity).
Protein: TRMA_VIBVU
Sequence: MATLDVNPQRYQQQLAEKVQRLTDMFAPYQAPELEVFESPDQHYRMRAEFRVWHEGEEMYYIMFNQETREKYRVDQFPAASRLINDLMPLLIDAMKDNESLRRKLFQVDFLSTLSGEILVSLLYHRQLDDAWIENAKALKQRLNDEGFNLNLIGRARKMKIVLDRDYVVEKLDVNGKPYTYQQVENSFTQPNGKVAEKMLEWAVDCTQESQGDLLELYCGNGNFSLALAQNFERVLATELAKPSVESAQYNIAANKIENVQIIRMSAEEFTEAMEGKREFRRLKDNGIDLKSYNCNTIFVDPPRSGMDVDTCKMVQGYERILYISCNPETLKENLDILSETHHITRFALFDQFPYTHHMEAGVMLERKA
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RS19_XANP2
Sequence: MTRSVWKGPFVDGYLLKKAEAASGSGRRDVIKIWSRRSTILPQFVGLTFGVYNGHKHVPVNVSEEMIGHKFGEFAPTRTYYGHAADKKSKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CRCB_DEIRA
Sequence: MSFPLWLWLALGGAVGAVCRQAAVLLLAPLVARTGFPAAVLLINVLGSFLLGLTLALTGRGVWPEAVRMTFGTGVLGAFTTFSTFSTELDGLLLRGQGGLALAYAALSVGLGLTAAVAGRVLGARL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCL_CHLAA
Sequence: MEAVTIVDVAPRDGLQNEPDVLEPATRVELIERLLAAGVPRIEIGSFVNPRQVPQMAGIDQIARMLIERGHNLAARTTNDLFRFTALVPNQRGYELAAAAGLRHVRLVLAASDGLNRANFKRTTAESLIEFSRFALNIRRDGLTFGVAIGAAFGCPFDGYVSPERVRAIAEHAVDIGAGEIILADTTGMAVPTQVAALCRTILDRIPDVTVTLHLHNTRNTGYANAFAAWQVGIRSFDAALGGIGGCPFAPRAVGNIASEDLVHLFNGLGVPTGIDLSALIAASDWLSATLGRPLPALVGKAGPVYPQVVSMAPYLS
What is the function of this protein?
Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis.  Catalyzes the cleavage of (R)-citramalyl-CoA to yield acetyl-CoA and pyruvate.
What are the official names of this protein?
(R)-citramalyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
Protein: RL6_STRGG
Sequence: MSRIGKLPIQVPAGVDVTIDGRTVAVKGPKGSLTHTVAAPIEVSKGEDGVLNVTRPNDERQNKALHGLSRTLVANMITGVTAGYSKALEISGVGYRVQAKGSNLEFALGYSHPILIEAPEGITFKVESPTKLSVEGIDKQKVGEVAANIRKLRKPDPYKAKGVKYAGEVIRRKVGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS15_CENSY
Sequence: MGRLHSHRHGKSHSIRPSSPKAPSWIQGPGEVEDLIVKYAKEGLAPSQIGSKLRDQHAIPLTRPITGKSVTQIMEEHGATPELPEDLNNIVQKAVGLQRHLRANKGDRRNVRSLELIEAKVHRLDVYYKRIGRIPKDWKYKSVVAQLE
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y4598_ARATH
Sequence: MASSKGSQNHRNLGCNGKQALLPPKSPFTGGPTFSADFVPSSVIGSKAVQKLGEGNANHHRTSSESFLIEEQPSWLDDLLNEPETPVRKGGHRRSSSDSFAYVDVPVGFDVDYTLWDGGRYNNNNGFSNHVRGPKESDYLRSQPVPFYPSAHLSKQKIRPWDSLPDSGARPNSSSGCLESSSITRSGSSGSLRDTEKAYSAADSKKDFINNFAKSSFEKRDNPLAKSATSEADTKRARQQFAQRSRVRKIQYIAELERNVQMLQV
What are the official names of this protein?
Uncharacterized protein At4g06598.
Protein: FBK70_ARATH
Sequence: MLTLGEDQIGRIGASSSWSRSKKLRVHRYEIPDLNVEPSLDWDGEETGEATKALSSTCLKPKDADYCLLNVPQLVYELEVEILARVPRFEYWKLKLLNKGFSRLLKSDEIFKVRRERGVVEPSVFMLSSGDTCWTMFDKGFGNCQKLPELPSDICFLHGDKESLCAGTHLIVTGKEEKSIALWRYELETSKWFKGPAMITPRILFASATCGTVVFVAGGLKIEGNGTMEVVDSVEKYDSKTKTWTLLRGMHKRRKFCSGCYLRGKFYVLGGRDENGQNLTCGESYDEKTNTWELIPDILKDMSFSSVQSPPLIAVVGDDLYSLETSANELRVYDANANSWKKLGDVPVRAKSNGGWGVAFKSLGDKLLVIGASAGPSRAETMSVYTSRPSANPANKLYWEESKRCCGVRFNHFILNCCVMIA
What are the official names of this protein?
F-box/kelch-repeat protein At3g27150.
Protein: YCFZ_ECOLI
Sequence: MKKFIILLSLLILLPLTAASKPLIPIMKTLFTDVTGTVPDAEEIAHKAELFRQQTGIAPFIVVLPDINNEASLRQNGKAMLAHASSSLSDVKGSVLLLFTTREPRLIMITNGQVESGLDDKHLGLLIENHTLAYLNADLWYQGINNALAVLQAQILKQSTPPLTYYPHPGQQHENAPPGSTNTLGFIAWAATFILFSRIFYYTTRFIYALKFAVAMTIANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR
What are the official names of this protein?
Inner membrane protein YcfZ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR4_CHAGL
Sequence: MSRYRGPRIKIIRRLGILPGLTRKIPKKSMKLRSLSLQSKSKKKDSQYRIRLQEKQKLRYHYGLHERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNTIFRLGMAPTIPAARQLVNHGHILVNGRIVNIPSYRCKPQDSITINTRTQTIALIQQNLGTTRKTKLPSHLMLRSTENSATVKQIVSRQSVGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PREP_YARLI
Sequence: MLRLKSLKKPVQAVVRRFATTSAPTLSVGDNIHGFNVLRTKEIPEFDLQATLLEHSTGAQHLHIARDDSNNVFSIGFKTNPPDRTGVPHILEHTTLCGSEKYQVRDPFFKMLNRSLANFMNAMTAQDYTFYPFATTNATDMKNLRDVYLDATLKPLLRELDFSQEGWRLENEDSKDKTSPIILKGVVFNEMKGQMSNAAYAFYIRYLEKIYPSLNNSGGDPLVIPELTYEGLKKFHADHYNPSNAKTFSYGDISVADHLEALNAKFENCEISKTPGNTERLPLEFSSAAENTRIVEEGPIDTLLDTSKQHKMSMSWLMGSPKDIYESFCVKIISSLLIDGHSSPLHQKLIDSGLGSSYSPNTGLDSAPGANIFSVGLQGVTESDLTKVETVILDTIKTTVAEGFDKGRIDGLLHQTELARKDQNAKFGMALMNGVLPGWFNQVDPLEALEWNSVLDRFNKDMEADPEFLQKVMKKYLLDNKYFHFQMNPNPDYEKNVQEKEDEILTDKLAKLTESDKEEIFETGANLEKMQEEPENLDCLPTLHVSDIPRSKPRVALEHTKNPYPIQWRLAPTNGLTYFHSISSLEGLPHEYYPFLPLFTSSLTFLGTKDKTMGQLEDEIKLNTGGLDFSVSCSSSPLSLPSSQLNFAMDGVALDKNVETMFGLFQELLRNTDFTNVEKLKTMIAASTANLSNALAQSGHSFAMLRAASDISPVKKIDDILGGVAQVRFLSELAAKSEQQLVDEVIPKLQEIAKFALTREQRFAVTCGQDMQTKNDELVRKFAESFETNESPFNISSLSIPMTTPTSTLFKLPFQVNYAGIAIPGVPYTHADGAPLQVLANMLTHKHLHREIREKGGAYGGGASYNPTDGFFSYYSYRDPNLERTLQTCQEAGEWSVKKDWSSSDLQEAKLSLFQRIDAPISVKSEGMALYANGLTYEQREKRRRQLLDVAVDDVKRVAKQYLVNPSGYSVAALGPGYETMDKKKWTVLE
What is the function of this protein?
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity).  Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity).  Also degrades other unstructured peptides (By similarity).  May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
What are the official names of this protein?
Presequence protease, mitochondrial, PreP, Pitrilysin metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
Protein: NCPP_SULIK
Sequence: MVTIALGSRNPVKINATKEALDVLKLNWDLIGIEVDSGVDKQPFCDQTYVGARNRALNVIRVTNADIGLGIEGGVCNVYGKFIANAVVYVITKEGLENFAISSSFTLPSSMVSLILQGKELGEASDIIFKTNNSKTKEGAIGLLTNNVINRKMLYVQPIVLALYPIYNTMINNTPF
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: Y3446_CLOBB
Sequence: MAKGGFPGGFGGGNMNNLMKQAQKLQKQMEDMQKDLETKEFETSVGGGAVSVTVTGKKEVKSINIKPEVVDPDDVEMLEDLVLTAVNEALRKAEEETASKMGKLTGGMPGGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CLL_A3446.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KTHY_SYNJA
Sequence: MFITLEGGEGVGKTTQQALLAERLQREGYACVSTREPGGTALGEALRELLLHGDPLTPLAELLLYAADRAEHVNKVIAPALAVGQVVICDRFTDSTLAYQGYGRGLNLEQIRQLNHLATGGLQPQLTLWLDLAPEVGLARSRLGDKLEQEHLEFHRRVYRGFQALAAAEPQRIVRIDAGGSPLEVAARIWSVVKPRLLAAVPRP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ZDH22_ARATH
Sequence: MSSEIEVVEEIQSNPKENGESSSKGIEEESLKNDVYTAAAYGDLEKLHRLVECEGSSVSEPDALGYYALQWSALNNRVAVAQYLIEHGGDVNATDHTGQTALHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVAAQYGQTAFLCHVVSKWNADPDVPDNDGRSPLHWAAYKGFADSIRLLLFLDAYRGRQDKEGCTPLHWAAIRGNLEACTVLVQAGKKEDLMITDKTGLTPAQLAAEKNHRQVSFFLGNARSLLEKRCDGSSPLGRLSKLGLAPVLWIMILLLLLVYTNSVVLASNLPKLTTGIGALAWLGFILATAGLFLFYRCSRKDPGYIRMNIHDPQTMKDDEPLLKIELNNPALLAGNWTQLCATCKIIRPLRAKHCSTCDRCVEQFDHHCPWVSNCVGKKNKWEFFLFLLLEVLAMLITGGVTLARVLSDPSAPSSFGAWMSHVASNHVGALSFLLVEFCLFFSVAVLTVIQASQISRNITTNEMANALRYSYLRGPGGRFRNPYDLGCRRNCSDFLVKGYNEDIECHEEDATQRPEGISMMQMQRNPNLQNGNGHVAIDVNPTHNSQSAHVHSANCSHSHNSKSKSDNVPLGLGLGLSRNPTRPVVSP
What is the function of this protein?
Palmitoyltransferase involved in cell growth regulation (Ref. 8).  Contributes to the palmitoylation of CESA3, thus regulating cellulose biosynthesis (PubMed:35644016).
What are the official names of this protein?
Protein S-acyltransferase 24, Ankyrin repeat-containing S-palmitoyltransferase, Palmitoyltransferase TIP1, Protein TIP GROWTH DEFECTIVE 1, AtTIP1, Zinc finger DHHC domain-containing protein TIP1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: PGMI_THEVO
Sequence: MQFSEELLTLKDQVRFDKSFKVGKYDKIVIAGMGGSGIAGRIFSEIYDEKPVFLVDDYDIPSFVDDKTEFIAISYSGNTEETISASEEAAKKHANVHAITSGGSLSKMGFDTIIIPSGLQPRSSIGYLLMPLVNTFIKPKIGDVDEAYRLLSETDKDNEEEKSIASEIYNGEHIPVIYGSRPFRAIAYRWKTQFNENAKVLAYSNYFSELNHNDTMPLKDTYRKDEFYFLVFRSDDSRFSKRITVTEKITGNSFRMVDVRGSSLLAKLFYLIHFGDYLTYHLAELRGVDPQDVSLIEKLKKEIA
What is the function of this protein?
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
What are the official names of this protein?
Bifunctional phosphoglucose/phosphomannose isomerase, Glucose-6-phosphate isomerase, GPI, Mannose-6-phosphate isomerase, Phosphoglucose isomerase, PGI, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the PGI/PMI family.
Protein: TRS85_YEAST
Sequence: MVFSYEHYMNLLFHLDNSKETVPPEIAKRIISNAIAPVITVTSTPLFDKHIQETYKVDSLYMLLRFFGGCVSDRDQANEAKVGQHEHEVCDASDSTDSIPKNKNLEVPNLSKKGSRSRSNSLFQRDSTQSQYIRFTRPLGDLIETRDANDMLFNYHSLEVFLDNYLKLVAANTDEMVPHNLLKKSIYHSFFSLAISSTNNLSPYETFNHPILSLIALDISNGEVYEDARDLLVNFKNLNHNTENFPIFMNTNEMLPVFLLCYNDDSQEEFEKCQALAKKLKKQLFVESILLALWKDSFIYDENSVIQLHQPVMSSLEEILFFLQAPTQTTLSLALINSIYDMLDYLVYDLMIPFMKRKVSFWEETILQPRKSLFNGAKFFKKFMNKNPVNGNHQHNSLTRDSQGNEYFASSSSEFLMRKLADWSMMLSDFKTAYSTYESLMDDLDAFPKYLASCIEWCAVSLLMGAQSIVTVKMIKNDINPLIERALATYENCSRIQRGKGKESNSLDVTEPVRSYETRCMILASELFLSLSNTWTSTPYAIQYLETILDECKLGPCSQIMVWERLSDCYNLRVDPRIKHRVGAMKKDAKDTEDLRGEHKYSTDHFTDEDILSEGLTRRRKAAFFRLIAAKKWAEQKQWRQVSWCLKDIESTYSEIKFLHGNGLILSKLKNQLNLKDVDSAPRPSEKNLTRTSVSFIG
What is the function of this protein?
Specific subunit of the TRAPP III complex that acts as an autophagy-specific guanine nucleotide exchange factor (GEF) for YPT1.  TRS85 directs the TRAPP III complex to the phagophore assembly site (PAS) that is involved in autophagosome formation.  Required for membrane expansion during autophagy and the CVT pathway.  Required for sporulation.  Has a role late in meiosis following DNA replication.
What are the official names of this protein?
Trafficking protein particle complex III-specific subunit 85, TRAPP III-specific subunit 85, Muddled meiosis protein 1, Sporulation protein GSG1, Transport protein particle 85 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRS85 family.
What are the subcellular locations of this protein?
Preautophagosomal structure.
Protein: ASNA_YERPE
Sequence: MKKQFIQKQQQISFVKSFFSRQLEQQLGLIEVQAPILSRVGDGTQDNLSGSEKAVQVKVKSLPDSTFEVVHSLAKWKRKTLGRFDFGADQGVYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERNLAYLKSTVNKIYAAIKETEAAISAEFGVKPFLPDHIQFIHSESLRARFPDLDAKGRERAIAKELGAVFLIGIGGKLADGQSHDVRAPDYDDWTSPSAEGFSGLNGDIIVWNPILEDAFEISSMGIRVDAEALKRQLALTGDEDRLELEWHQSLLRGEMPQTIGGGIGQSRLVMLLLQKQHIGQVQCGVWGPEISEKVDGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_CROS8
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEIIEAVENSCFAKGYTLILGNAHNNLEKQRAYLSMMAQKRVDGLLVMCSEYPQPLLSTLEEYRHIPMVVMDWGEAKADFTDSVIDNAFQGGYLAGRYLIERGHRDIGVIPGQLERNTGVGRFSGFMKALEEAAIKVPENWIVQGDFEPESGYRAMQQILSQPQRPTAVFCGGDIMAMGAICAADEMGLRVPQDISIIGYDNVRNARFFSPALTTIHQPKETLGQTAFNMLLDRIVNKREESQTIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: CINAL_PROMA
Sequence: MSSYINKNQSVEILCIGSELLLGNILNSNAKWLAEQLAFIGLPHYLQSVVGDNSQRLLRIILEASRRSRVLITTGGLGPTPDDLTIETIASAFNVKLTKNNDILKDIKRKLNSHSHVSENNFKQALLPEGAEIIPNKSGTAPGIIWTPIVDFTIISLPGVPAEMKQMWIETAKPWLNVNFPERKSLTSKTLKFAGISESFLAENIVDLLDNKNPTIAPYASLGEVKLRLTAQAKTTSEAKRLIEPIEVELLKRFGLKCFAKNDETLSEIVIGLLSKRGETISLAESCTGGNLAAAFTGTPGASEVFLGGIVAYNNSIKENVLGVPIELIKKHGAVSQPVAKEMALGILKIFNTDWSIAISGIAGPSGSTLNKPIGRVEIFIAGPNVNESIQENFGSYRAREEIQKLSVVRALDQLRLFLLRRS
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: TLP9_ARATH
Sequence: MTFRSLLQEMRSRPHRVVHAAASTANSSDPFSWSELPEELLREILIRVETVDGGDWPSRRNVVACAGVCRSWRILTKEIVAVPEFSSKLTFPISLKQSGPRDSLVQCFIKRNRNTQSYHLYLGLTTSLTDNGKFLLAASKLKRATCTDYIISLRSDDISKRSNAYLGRMRSNFLGTKFTVFDGSQTGAAKMQKSRSSNFIKVSPRVPQGSYPIAHISYELNVLGSRGPRRMRCIMDTIPMSIVESRGVVASTSISSFSSRSSPVFRSHSKPLRSNSASCSDSGNNLGDPPLVLSNKAPRWHEQLRCWCLNFHGRVTVASVKNFQLVAVSDCEAGQTSERIILQFGKVGKDMFTMDYGYPISAFQAFAICLSSFETRIACE
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Confers sensitivity to ABA during seed germination and early seedling development.
What are the official names of this protein?
Tubby-like F-box protein 9, AtTLP9.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: RBM42_BOVIN
Sequence: MAGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVTGIPTAVPAVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPATPRELGLGLGLGLKEKEEAVVAAAAGLEEASAVVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLSEDKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR
What is the function of this protein?
Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.
What are the official names of this protein?
RNA-binding protein 42, RNA-binding motif protein 42.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM42 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Upon stress response, localizes with HNRNPK in cytoplasmic aggregates of stalled translational preinitiation complexes called stress granules.
Protein: TIM8_DEBHA
Sequence: MSQISQTALASLDESSRKDIMQFIESENSKSKVQMSIHNFTDMCFKKCNANKPITSGTLDSSEEQCLTNCLNRFLDTNIKVVQALQGAQK
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM8.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.