PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_DICTD
Sequence: MGKNFLLEIGTEEMPAHFLDPAIKQIYDFSLNYFENQKISFEDIKTWATPRRLVVYIKNLSEKQESQEEEIRGPAAHVGYKNGVWTEVAKRFAEQYGASLEALYIKETPRGKYIFLKRIKEGVNTLEILPDYAVSLLKNIRFPKMMKWGNVDFYFGRPIRWIVALYGSEEVKFEVAGVKSSRYSRPPRFLPQTPIEIKDADSYIDLMKENYVIVDQNERKNEILRHIKEIANSNSLTLSYDEDLLEEVTYLVEYPTALLGQFDSKYLTLPEIVLIVTMEKKQRYFPLRDKEGNLINKFIVIRNGTENYKEVVIQGNEKVLKARLADAEYYYNEDIRCPLEKYSEKLSGIIFQEQLGTIKDKVERVRILVREIANILELSTEEKEILERAVDLYKADLGTLMVSEYPELHGIMGSIYAKISGEREPIPQIIGEYIYPRTLEDQIPKNPLSTVLGIADRVDSLTGYFALDLFPTGSEDPIGLRRISGGLLRLLLETDFKLNLRNLFMKSFEVYKFSDKCPISQIEKGMLFIGQRLRNLLLDKYPNDIVEAVMEVGYDELWKLKRRVDFIREFKEKDPYEKLKRALNRLYRILPKDFSPKEINENLFNSPFEKELYRDYVKINKEISKEILKGNYKVLLGYDFLKEFSDHIESFFDHVLVMSPNEEEKLNRLSLLFAIKSLFWEVLDWSKLN
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPC2_SCHPO
Sequence: MSLLSGDQRIICLEIPLQGKENVHINFAKEVEKLYGPSVQENSKKNDLSDSADSEGESTHVDEQQAANGAADGTQTIKKKKRKRRYADEYYDRTDPFIDDAELYIEEKAAATKDGFFVFSGPLVAEGDTVKIERSKKTKKKKKTSLSNATHPAPAVSAVVASADASFDDSRDIESEDEQPLRTLSIEMAAKNALKEAKRENAKVPKDVSKKEAKTTKSKEKATKKTSSSVPKQSTGENTKKAVKLETPLTSTPPIPPLSEPKHSPATVNEHISPPSALTNPSTEELKPSTSLPIDQGNASVVSKPTQQVSIVLSQNASLPVDEHQAEPEKSIPTSSIP
What is the function of this protein?
Component of the HIR complex, which functions as a histone chaperone that cooperates with cia1/asf1 to promote replication-independent chromatin assembly.
What are the official names of this protein?
Histone promoter control protein 2.
What is the protein family that this protein belongs to?
Belongs to the HPC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHCD_ECOLI
Sequence: MLKKTLLAYTIGFAFSPPANADGIEIAAVDFDRETLKSLGVDPNISHYFSRSARFLPGEYSLIVSVNGEKKGNIATRFDENGDICLDQAFLQQAGLKIPSEEKNGCYDYILSYPGTTITPLPNQEALDIIVSPQAIIPIGLDLTNAATGGTAALLNYSLMSSRAEFSNGSSDYSQAALEGGININDWMLRSHQFLTQTNGTFSNQNSSTYLQRTFTDLKTLMRAGEVNLNNSVLEGASIYGIEIAPDNALQTSGSGVQVTGIANTSQARVEIRQQGVLIHSILVPAGAFTIPDVPVRNGNSDLNVTVVETDGSSHNYIVPSTLFNQHVESFQGYRFAIGRVDDDYDESPWVISASSGWNLTRWSAMNGGVIVAENYQAASIRSSLVPLPDLTVSSQISTSQDTKDSLQGQKYRLDANYNLPFSLGLTTSLTRSDRHYRELSEAIDDDYTDPTKSTYALGLNWSNSILGGFNISGYKTYSYDGDNDSSNLNINWNKAFKHATVSVNWQHQLSASENNEDDGDLFYVNISIPFGRSNTATLYTRHDDHKTHYGTGVMGVVSDEMSYYVNAERDHDERETSLNGSISSNLHYTQVSLAAGASGSDSRTYNGTMSGGIAVHDQGVTFSPWTINDTFAIAKMDNNIAGVRITSQAGPVWTDFRGNAVIPSIQPWRTSGVEIDTASLPKNVDIGNGTKMIKQGRGAVGKVGFSAITQRRALLNITLSDGKKLPRGVAIEDSEGNYLTTSVDDGVVFLNNIKPDMVLDIKDEQQSCRIHLTFPEDAPKDVFYETATGECQ
What is the function of this protein?
Involved in the export and assembly of a fimbrial subunit across the outer membrane.
What are the official names of this protein?
Uncharacterized outer membrane usher protein YhcD.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SFSA_SALPA
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQFGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: GATD1_MOUSE
Sequence: MPLGLKPTCSMCKTTSSSMWKKSPQGEILCHHCTGRGGGGAGVAGGTGGGGGGGGGFGTTTFATTSAGPSQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAEKKVSTKGKGRRHIFKLKNPIKAPESVSTIVTAESIFYKGVYYQIGDVVSVIDEQDGKPYYAQIRGFIQDQYCEKSAALTWLIPTLASPRDQFDPASYIIGPEEDLPRKMEYLEFVCHAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITIKETVANHL
What is the function of this protein?
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
What are the official names of this protein?
GATA zinc finger domain-containing protein 1, Ocular development-associated gene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: GINT1_ORYSI
Sequence: MAGRRAMRPSGSSMRGVVARLAAARSPAVSFLVAAAAGAALVGGVYFWLVVSSFRLPDSRAVGCLPDGEGSWAIGMYYGKSPLELRPIELEGRSNGNSSAWPVANPVLTCATPTEGGYPSNFVADPFLYVQGDTLFLFFETKTVSTMQGDIGVARSLDQGATWEFLGIALDEAWHLSYPFVFKYENEIYMMPEGNKKKELRLYRATKFPLEWTLEKVLIDKPLIDSSLVQYDGLWWLFASDFTRHGIEKNAELEIRYSNSPLGPWSEHKQNPIYRSDKSLGARNGGRLFIFEGSLYRPGQDCSGTYGRKVKLYKIEKLTKEEYKEVPVNLGIEEAKKGRNAWNGMRYHHIDAQQLASGGWVAVMDGDRVPSGDSTRRSLFGYMGFLVAVALVTFVGFVKGAISCYIPPSFWVPLTRRSELSRILPVHRFNLKIRRYSTSIGRNISATKARLSEKTWSNTLFFCVIALIGIVNVCIAVHFLLGGNGAEEAYTHQGQHSQFTMVTMTYEARLWNLKLFVEHYSRCESVREIVVVWNKGNHPTSDAFDSTVPVRIRVEEINSLNNRFRGDPLIKTRAVLELDDDIMMTCSDVEKGFKVWREHPERMVGFYPRMIDGDPLQYRNERYARGKKGYNLILTGAAFMDSEFAFSKYWSQEAKEGRDYVHKNFNCEDLLMNFLYANASSSRTVEYVHPAWAIDTSKLSSVAISRDTQKHYDIRTKCLAKFASIYGPLPQKWLFGMREDGWDK
What is the function of this protein?
Essential protein.  Glycosyltransferase that mediates the glycosylation of glycosylinositol phosphorylceramides (GIPCs), the major sphingolipids in the plasma membrane; acts as a HexN(Ac)-specific GIPC sugar transferase.  Responsible for the glycosylation of a subgroup of GIPCs found in seeds and pollen that contain GlcNAc and GlcN (GlcN(Ac)).  Maybe involved in the maintenance of cell-cell adhesion.
What are the official names of this protein?
Glucosamine inositolphosphorylceramide transferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 64 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS12_DESAH
Sequence: MPTINQLVRKGRKKAEKKQSTPALKGGPQKRGVCTRVYTSTPKKPNSALRKVARVRLTTGMEVAAYIPGMGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDTLGVEDRKQGRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS18_DESAP
Sequence: MKRDRGRRKKKICSFCVDKIAVIDYKDTPRLKKYITERGKILPRRITGNCAHHQRMLTVSIKRSRHMALLPFSTD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYRE_ENT38
Sequence: MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIDFDLLFGPAYKGIPIATTTAVALAEHHDRDVPYCFNRKEAKTHGEGGNLVGSELQGRIMLVDDVITAGTAIRESMEIIQANGASLAGVLISLDRQERGRGEISAIQEVERDYGCNVISIITLKDLIAYLEEKPEMADHLASVRAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RRAA_SALTI
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFEDNGLLYDLLEQNGRGRVLLVDGGGSVRRALVDAELARLATQNEWEGLVIYGAVRQVDDLEELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIQ_LUMTE
Sequence: TITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Ubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL27_NEIM0
Sequence: MASKKAGGSTRNGRDSEAKRLGVKAYGNELIPAGSIIVRQRGTKFHAGDNVGMGKDHTLFAKVDGYVEFKTKGALNRKTVSIRPYTGSEE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ATX1_PLAFA
Sequence: MHLMCTGLRNEKLINDRKILYGECNLNIKSDSFIILLFKEIMNPFFIFQIFAMIVWSLDNYIEYTISILFITSISIILELKNTIKNQKKIKNMLNYTCPINVYRYNTSYIISSSELVPGDIYEIKNNMTIPCDTIILSGSVTMSEHMLTGESVPIHKERLPFEGNAIINKNNKYDSNDEKDDYLRIYNNHASINMIKRNHLIEETLGKKDREYKSNTHDLCSMNKLCYINNTYDDVHMKNNKMDYNNNNNNKKKKKINNLNFVKGTYINSNDLLYDDKIGVNIFEDDVNNMKHKFNQRNINYYNKDTNNLEYNNKHRYIYDCLLKKVEAISQKNKIIYSNEDINKYMLYGGTYVLSLYNINKIKYNNKEENRILGLVIKTGFITTKGKIVNNILYHKKKELNLINDSYKFLIILIIYALFSVFILLYITLSNNEYTNHIIIKCLDIITDAIPPALPTTLTVGISIAISRLKKKFSISCLCPHKINIAGQINTMVFDKTGTLTENNLQFIGIITQNKKNKNMLSDFIHIKEMNTESYIHSKDDNMIHNKNSIISEYYIKDNMKNLHTSSKKKSITKERSNFLVQTIKSCLLKDHYIKEKKKEYYTNNTYCNDLHINDSTCSSYLLNSETKDAYCEYYNIDHLCDINKKNMDINSKNELMGKYSKNELMGKTIKNELMGKYSKNELMGKYSKNELMGKYSKNELMGKYSKNELMGKYSKNELMGKTIKNQVGVDTNIYHMNCDNDYNYDYPCDYNCNNCNDTYHRLEYHNINKDNSFNIPPEKNKSYNNISEHIKINYPLLFEALACCHTLSKVNNKIMGDVLEILMFNFTNCDMLINNNSFIIKEKKKNCSYDFQKIDGDKNIGANDERCHLNNNLVSYNILKRFEFQSRLQRMSVIVKSTYGNNNDDNNDDDNNNDDDNNDDNNNDDNNNDDNNDDNNNNNYYYNIFCKGSPEKIKELCLKSKIPNNYDEILNKYTKQGMRILSISYKRVKSKNINLLNVKRSFVESNLHFLGFLIFTNNMKKNAPDIIHNLQTSGCQCIMSTGDNVLTSIHVAKKCGIINSNVESIIIGDVIPVVGKNNKQKKKLVWYNHKNDTYLKGHDKTCIDNEFTSIQSQMNSDNICGDNICGDNIYGDNICGDNIYGDNINGDNINGDNIYGDNINGDNINGDNINTYDNIYGDNYNLDYCPTEYHKCTYNNSILYRNNFLYKKENKKDKNYKNISTLYEHRTNDIQFDKLCDILINKDPRNVNIVLTGKAFIFLKKKFYSFHLPYYEECKNIVHYIMKKKHKKIKNIINNHNSNLYYHYNIIDTFVKRMNKEYMCFNKLLYKIQQKLLYNLIHNLYKKKKYMNNYYDIDEVHLIGNNNNNNNKNNSKEKKLPLKNKMKHIRKNESNDNITFNTYTSNNIHLSKYKYVHHKNYYYPDSCTNLRKKKNSLFYNLKKYIYYEKKKYLQHCLLKHDNYKKVELPRIKDINYSYQMESIKTRNFIHSLSEQFAFSNLILSFYIIKNDDNNVYNKNYIYNKNYIYNKNSICNKNYICNKNYIYNKNNIYNKNNIYNKKNILTHAKSVLLSGSSKKFLKFFSNIIRRHKLKEKKNKKNIKRYKMNHVNNTSKGHIILNMCTHGFKKDYSSLKNKYRIVNNKRYMLKNDNVYDRHMYNLTDMYRGTQYGCSKKKNKNIYMNNNNNILKNKINRFLEHLLVDKCKRNICHKYTDIKNIKLSIYEYILRTCTVYARMKPKDKSDLILSLKKLPNNSYVGMCGDGANDCLALSCADIGISLCNNNESSICSSFTSNKLCLHSIVHILIEGRASLVNSFQLFKFISLYSIMQCSQVLILYSISNKLTDNQYIFIDIVTILPLSIFMCWTSASEKLSKNIPIGKLFSFPILISIYGQIIIQLFFVMISLVVLMNLSFYKYDKNKVMKEKSDDTYLYKAQKYTLIYSLLFSKFVYVYIFKYKE
What are the official names of this protein?
Probable cation-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS9_STRA5
Sequence: MAQAQYAGTGRRKNAVARVRLVPGTGKITINKKDVEEYIPHADLRLVINQPFAVTSTQGSYDVFVNVVGGGYAGQSGAIRHGISRALLEVDPDFRDSLKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: THP1B_XENLA
Sequence: MVQSCSAYGCKNRYDKDRPISFHKFPLKRPLLCKKWEAAVRRADFKPTKYSSICSDHFTADCFKRECNNKLLKDNAVPTVFALAEIKKKMGKAVKKEQLPAELEPVPAVPEVDPAIGLLLPPLYTPSHIAVICDHNYTVEDTVHQRRRIQQLEEQVDKLRKKLKIANQKCRRQERSLEKLEKEVSEYREAKGSGYVIFPGNYYEVLNENEYKELTPEITYKEIIL
What is the function of this protein?
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression.  Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes (By similarity).
What are the official names of this protein?
THAP domain-containing protein 1 B.
What is the protein family that this protein belongs to?
Belongs to the THAP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: CRE18_PHYIT
Sequence: MSKLFYAFAVLAVHVLTSSPTTAASNLPVNLVTGPAFTTPAGAAHRRFLRSIHEGEDSLKPSAFSEERTALRAMDYLLKPKHKKLAAALKKSTSKHKLSVAPEKMKSIQVLGDPKNPEREWFKRLYNSKRGDPQTLRKLGQFKTEAQLSRYIKFYVVCRTCIACYSSGRSDSCHRTPRMVRTVGVGCRD
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein CRE18, Core RXLR effector 18.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: PIN_BPT4
Sequence: MITVDKWFRINRADTGLCNYWPELSAGTVFKVRELVKECEDDIEPDTGIIEIELSDGKIINIYDKPITYWCLWNTESVENGEIEEVVERTNQVVQKPKADFQGERISYALAKLAAQENNDGYEGNLMQAAAEYIEWLETQISFSDRMIQQYKRLHQMFYNT
What is the function of this protein?
Plays a role in the inhibition of bacterial toxin-antitoxin system by blocking the action of host Lon protease.
What are the official names of this protein?
Host protease inhibitor, Protein pin.
Protein: HSLV_BRUA4
Sequence: MIEHHPTTIYGTTIVTVRKGNKVVIAGDGQVSLGNTVMKGNARKVRRIGKGNVIAGFAGATADAFTLLERLEAKLEQYPDQLMRASVELAKDWRTDRYLRKLEAMMLVADSKVTLALTGTGDVLEPEHGVMAIGSGGNYALAAARALVDTDKSAEEIARKAMDIAADICIYTNHNIIVESLDAE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_SALPB
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MURD_STRT1
Sequence: MKSITQLENKKVLVLGLAKSGEAAARLLAKLGAIVTVNDGKAFEENPSAQSLLEEGIKVVCGGHPLELLDENFELMVKNPGIRYDNPMVARALEKEIPVWTEVELAYLVSEAPIIGITGSNGKTTTTTMIADVLNHGGKSGVLSGNIGFPASEVAQSVTNQDTLVMELSSFQLMGIESFHPHIAVITNLMPTHIDYHGSFEEYVAAKWNIQNEMTSDDFIILNFNQDLAKELATQTNAQVVPFSTVEKVDGAYLENGGLYFKGELLMHADELGVPGSHNVENALATIAVAKLSGVSNQAIKETLSSFGGVKHRLQFVDTIDDVKFYNDSKSTNILATQKALSGFDNSKVILIAGGLDRGNEFDELIPDITGLKKMVILGESAPRVKRAADKAGVTYLDAKDVADATRIAFEQASAGDVVLLSPANASWDMYKNFEVRGDEFITTVERLKG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM81_BOVIN
Sequence: MKTSATSFIPGSLVLAFCLPVVATSPKTLAIPEKLQEAVGKVTVNATTCTVICGLGFKEETVCEVGPDGVRRKCKSQRLECLTNWLCGMLHFTLLIGKEFKLSCLSPDILEIGQGAFRFTWRLARGIISTDDEVFKPFRASSYFIKFQSIQEYDSGTYRCDVQLLKNLRLVKRLYFGLRVLPPNLVNLNFHQSLTEDQKLVDEGLEVNLDNYSRPQHPPWKKKVAIAVGIGVAGGVTGGVLVSIVLCGRLSVIHSSASLETLQALLPKGGMLRKPD
What are the official names of this protein?
Transmembrane protein 81.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYWM_MOUSE
Sequence: MALFSVRKARECWRFIRALHKGPAATLAPQKESGERVFSGIQPTGILHLGNYLGAIESWVNLQEEYDTVIYSIVDLHSITVPQDPTVLQQSILDMTAVLLACGINPEKSILFQQSKVSEHTQLSWILTCMVRLPRLQHLHQWKAKAAKQKHDGTVGLLTYPVLQAADILCYKSTHVPVGEDQVQHMELVQDLARSFNQKYGEFFPLPKSILTSMKKVKSLRDPSSKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYEPDSRAGVSNMVAIHAAVSGLSVEEVVRSSAGLDTARYKLLVADAVIEKFAPIRKEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGIL
What is the function of this protein?
Mitochondrial aminoacyl-tRNA synthetase that activate and transfer the amino acids to their corresponding tRNAs during the translation of mitochondrial genes and protein synthesis.
What are the official names of this protein?
Tryptophan--tRNA ligase, mitochondrial, (Mt)TrpRS, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HPAP_RALSO
Sequence: MTQAVRLWRPQPVDPAPPTRRRTPLRTPGPHDALPYVPPPRPEPPEPVEDDFPEPRQDTPASDPPPEARTDASPPQPAADPDASLHTAAIASRLVRTCSEIGAGETMTEHLARLLSQFCASQAIRSGGECWEISLDLDPKILPETRLTLRLSPHTLSLRFEAGHPRSRHLLSEHGDTLRQRIHALLRQQVDVELELW
What are the official names of this protein?
HRP-associated protein.
Protein: PAU5_YEAST
Sequence: MVKLTSIAAGVAAIAAGASAAATTTLSQSDERVNLVELGVYVSDIRAHLAEYYSFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYSSRLKPAISSALSADGIYTIAN
What are the official names of this protein?
Seripauperin-5.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MOBA_RHIL3
Sequence: MAEFSLDKSHIAGVVLAGGRSQRMGRDKAGVMLGAESLLRHALTRLSQQALHVAVNADAAAEDVPVVPDRFPGKAGPMAGIHAAMVYAADLPSITHVVTVSVDCPFFPADLVARLAAAIEHPSQIAIAASEGRSHPVFGLWPVTLAADLEAWIATDEKRRVRDFLLRHDVTEVAFPLHPTRASLLDPFFNINTPDDLVEAERWLEALRA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHDAG_HDVD3
Sequence: MSRPEGRKNRGGREEVLEQWVSGRKKLEELERDLRKVKKKIKKLEDEHPWLGNIKGILGKKDKDGEGAPPAKRARTDQMEVDSGPRKRPSRGGFTDKERQDHRRRKALENKRKQLSAGGKNLSKEEEEELRRLTEEDERRERRIAGPQVGGVNPLEGGTRGAPGGGFVPSMQGVPESPFTRTGEGLDIRGSQGFPWDILFPADPPSSPQSCRPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication.
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place.
Protein: PYRG_PSEA8
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKITMLKLDPYINVDPGTMSPFQHGEVFVTQDGAETDLDLGHYERFVRTTMTQNNNFTTGRVYMDVLRKERRGDYLGATVQVIPHITDEIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEIGAKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLVCRSDHPIDVSSRRKIALFTNVEERAVIALEDVDTIYRIPSVLHAQGLDDIVVERFGLECGQADLSEWDRVVDAKLNPEREVTIAMVGKYMELLDAYKSLIEAMTHAGIQSRTKVNLRYIDSEDIEQQGTSLLEGVDAILVPGGFGLRGVEGKISTVQYARENKIPYLGICLGMQVAVIEYARNVLGWSDANSTEFDKSSGHPVVGLITEWQDATGATEIRTEASDLGGTMRLGAQECQLQTGTLVHDCYAKDVIVERHRHRYEVNNNLLPQLEQAGLKISGRSGDGALVEVVEAPEHPWFVACQFHPEFTSTPRDGHPLFSGFVNAALKYSGKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MLRSB_DANRE
Sequence: MAPKKAKKRQQAEGGSSNVFSMFEQSQIQEYKEAFTIIDQNRDGIISKDDLRDVLATMGQLNVKNEELEAMVKEASGPINFTVFLTMFGEKLKGADPEDVIVSAFKVLDPEATGTIKKEFLEELLTTQCDRFTAEEMKNLWAAFPPDVAGNVDYKNICYVITHGEEKEEE
What are the official names of this protein?
Myosin regulatory light chain 2, skeletal muscle isoform B.