PharMolix/UniProtQA huggingface dataset:
Protein: WASF2_BOVIN
Sequence: MPLVTRNIEPRHLCRQTLPSVRSELECMTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASRVSSLAERVDRLQVKVTQLDPKEEEVSLQGINTRKAFRSSTVQDQKLFDRNSLPIPVLETYNTCDTPPPLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKPSRYPPTLVYQNGSIGSVENVDAGNYPPPPQSDSISPPSPSFSEDNLPPPPAEFSYPADNNQRAGLKRSSVVSPSHPPPAPPLGSAPGPKPGFAPPPAPPPPPPMINTPPPPPPGGFGSPATPPPPSPPSFPPHPDFAAPPPPPPPPAVDYSTLPPPPLSQSAGGAPPPPPPPPPPGPPPPPFSGADGQLAAPPPPLSDTTKPKSSLPPVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVATILSRRIAVEYSDSEDDSSEFDEDEWSD
What is the function of this protein?
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.  Promotes formation of actin filaments.  Part of the WAVE complex that regulates lamellipodia formation.  The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).
What are the official names of this protein?
Actin-binding protein WASF2, Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Basolateral cell membrane. Note=At the interface between the lamellipodial actin meshwork and the membrane.
Protein: NDRG3_RAT
Sequence: MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGLNHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMKSIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIERPILGQNDNRLKTLKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPDVLDRHQTMEVSC
What are the official names of this protein?
Protein NDRG3, N-myc downstream-regulated gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
Protein: RNC_PHOLL
Sequence: MNPIVINRLQRKLGYTFDQYDLLIQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGYRRESILADTVEALIGAIFLDSDIQSIERIILSWYETRLNEISPGDKQKDPKTRLQEYLQGHHLPLPSYLVVMVRGEAHDQEFTIHCQVSGIEQPVKGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_ALKMQ
Sequence: MNNENLVIYILSDSIGETAEQVAKAAISQFDTEDYEIRRFPFITEKHHIDEMLQEAKKENSVIVFTMVVEELRNYIMEEAEKMQIRSIDIMSPVLHAMGGALTTTPKREPGLIRRLDEKYFRKVEAIEFAVKYDDGKDSRGLAKADIVLVGISRTSKTPLSMYLAHRNMKVANVPLVPEVTPPKELYEVPSQKIIGLTTNPIKLIEIRQERLKALGLKNEASYASMERILEELEYAEGIMKRIGCPVIDVSTKAVEESAGIILEIFRDRGYNMPNGR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: Y484_MYCTO
Sequence: MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR
What are the official names of this protein?
Uncharacterized oxidoreductase MT0502.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: IDHC_PIG
Sequence: DLAGEIHGLSNVK
What are the official names of this protein?
Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TCPB_MACFA
Sequence: MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit beta, TCP-1-beta, CCT-beta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_COLP3
Sequence: MTIKSVSVKGIDVANEQPFVLFGGMNVLESRDLAMKIAEHYVEVTQKLGIPYVFKASFDKANRSSVNSYRGPGLDEGLKIFEEIKSTFNVPIITDVHESYQAQPVSEVVDVIQLPAFLARQTDLVVAMAKTGAVINVKKPQFLAAHEMKHIITKFGEAGNENIILCERGSCYGYNNLVVDMLAMDEMKNYAPVIFDATHALQKPGGRSDSADGRRAQAAQLARSGMAIGIAGLFIEAHPDPSAAKCDGPCALPLDKLEPYLAQMKALDDLVKGFTPLITD
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4QC_SINFN
Sequence: MKPYTDFEPPPALAVTPAGRRRLAELQKLHSAAGESLLVDEEAAAAGILRIEFSWPLNDGRTIGLRAVYPDTFPRLRPHVFLTCDPSEYPERHCGSEGALCLLGRDTRYWQANMSLAELLDENLAHVLDGTGAEDPQGEPIEYWWNSLGQASGSFVLVDSRWKLSGYDEGTVDVLVNASRTEIGRTIRAAILSVRAGDGSLLGERVAPLPAAVSSTAIRAFPWRRDDQLSLPTGSAEQTVGKVAYGKTYVTCDGADIRLSFTISRTELQHNEHGDAWVCGMAVREHISHSSRRGPRRKDTVPSIVPVFRDGEIDIGYRVPSVASLRGKRIAVVGLGALGSPAAVELARNGCTSLHLMDDDVVEPGNTIRWELGASSWGTKKQDALKRFIEREFPWTSVLAVPHRIGLPNCDPHIPGETDRLNELLDSVDLVVDASAAPGVTYLLGDICRERGLSLISVFASPNLHGGAVVFHHPESGCPVCMAHANETPEGKSGHIPYPNGMNDESTLVQPPGCSELTFTGASFDLKELSLETVRMAVDVLSSPDEWTVSEVRTVNLHNVKRRMPPSWRIDPLERHPDCGCRS
What are the official names of this protein?
Uncharacterized protein y4qC.
Protein: AMPA_VEREI
Sequence: MNFDLKTLELAAAAAEKCDLLLVLIPEGFTPGQDALSTLAALALKNGDLLLKAGKHLQLYQVPAVAARRVILLGVGDGTARAVRQALLALGAEIKKPQTKRLVLCFAAALKAGVASAAVQAVAEASYVYTTTKSKAEARSLSRCVLGVPDAAGARPGFDCGVALVAGVEFAREWSNRPANHATPSLLADAAKTLGRLPHIQCKVHGPAQVRRLGMGAFVAVARGSEQPLRFIELRYSAAAKDQAPIVLVGKGITFDSGGISIKPAPEMDEMKFDMCGAASVLGVFRALGELQPAINVLGLIPACENLPDGRAIKPGDVVTSMSGQTIEILNTDAEGRLILCDALTYAARFKPAAVIDIATLTGACVVALAGVRSGLFANDDDLAVSLYEAGEAALDPCWRMPLDDDYADGLKSHFADMGNTAGRSGGAITAAKFLQKFVAGMRWAHLDIAGIAYKSGPAKGATGRPVGLLVHYLLAQAEAMAQQAPVAPAAPAAPAAPAARPAAKRTGRSQGGLKRTAP
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCY32_CAEEL
Sequence: MFGFIHESIRQLVIRNYGEDTWTQVLERSGFESGKENIMNHYYSDTDTYVLVDSVSLVLKVTKDQVWEMYGGFLITYSMEIGWDELVRSMSPNLKGFLDNLDSLHYFIDHVVYKANLRGPSFRCEETPDGTLLLHYFTGRPGLYHIVKGVVKEVAKRVFDLDITLVVQGRTQRSVHMNNGERVEEHVVFLINNLSEPRRDSEGSEVSLLTSTNANFPTIVDDTLGISLDDFSKALPYHFVIDESCKLVQCGSELHNHIPNELLQPGTPILRIFEINRPQIPLDFENICNFINAVFVLQVKTSPLKKKHMDAMSQEELKQEMETLDEDATNELTQGHHLKLKGQMMLLASKKHIIYLCSPYVTSINELMQYGMRLTAMPLHDATRDLILLNQQRLSDVEVNLQLEANNEQLETMTRELELERQKTDSILKDMLPRRIAQQLLSGEHIEACEHEATVMFCDLPAFQQAIPQCSPKDIVNMLNEIFRKLDRIVVIRGVYKVETVSDSYMAVSGIPDYTPEHAENMCHVALGMMWEARSVIDPVSKTPFLLRIGIHSGTITAGVVGTVHPKYCLFGETVTLASQMESLGMAGKIQCSKWAYQKAMETGRFEFSPRGRIDVKQRGLTETYFLTRSLKKSIWEIIDHDRDINVNSIEGYEELETAIENAVTIKSALPRPDQRNSAACSIS
What is the function of this protein?
Synthesizes cyclic GMP (cGMP) from GTP (By similarity).  Influences aerotaxis responses, aggregation and bordering behaviors (gathering around the edge of a bacterial lawn) in combination with other soluble guanylate cyclases.
What are the official names of this protein?
Soluble guanylate cyclase gcy-32.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_MYCS2
Sequence: MAVVPIRIVGDPVLHTPTEPVPVGPDGSLPDDLPALIQDMFDTMDAANGVGLAANQIGVAKRLFVYDCAPTRGQTTRRRGVVINPVLETSEVPETMPDPDEDEEGCLSVPGENFPTGRADWARVTGLDADGSPITLEGEDLFARMLQHETGHLDGFLYLDRLVGRYARAAKKAVKRNGWGVPGLSWMPGEVPDPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YBEY_ONYPE
Sequence: MIIKIHNQTSFCITPFKSLLIKMFLPIKEKKLMHLIFVTNEKIQELNSFYRQKNYPTDVLSFPNDLTFFAGLEDNSLGDVFISFSKAQVQAQTAKHSLEREIAFLAVHGFLHLKGYQHRTEEEFQIMLALQEKILQNVGLNLDKTT
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_HAHCH
Sequence: MKADLLQRFIFDELDIRGELLVLKKTVQDALSRHDYPQAIQSLLGQALSAGLLLSATLKIKGDTTLQATGEGELRLLMAEATHRRTARGIARWEGAPDSTSLKQLLGNRAALAITIAPQNGQRYQGIVPLSSDSLSACLEEYFERSEQLATRIWLYESNGCWGGLLLQQLPAARGGEYSAENWERIVALSATLTADELFSLPAEEVLHRLFHEESVRVLQEEPASFWCSCSEERTLEVVKSLGREEAFSILDESGEIEMNCQFCLQRYSFGRERIEQLFDSPTLH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ALIFM
Sequence: MSNEENKVNEEAVVEEQVEAVGTEADVEWNESAEDSQEAKIAELEAALLASQAQIKEQQDTVLRAKAEEQNVRRRAEEDVDKARKYALKKFAGELLPVLDNLERALENGDKENEAAKALLEGVELTLQTFVSTVEKFGLTVINPMGEAFNPELHQAIGMQASPDHESNTVMIVMQKGYTLNDQVLRPAMVMVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_EXISA
Sequence: MDERLLSQSHQQYEDSEEWSLRPQRFEQYIGQEKAKGNLSVFIQAAKLRSETLDHVLLYGPPGLGKTTLAQIIANEMGVGIKTTAGPAIERPGDLAAILSTLEPGDVLFIDEIHRLSRTIEEILYPAMEDYCLDIVYGQGEMARSVRIDLPPFTLVGATTRAGMLSAPLRDRFGVTLKLEYYETHELAAIVSRTAQLFRLSISPEASGAIAKRSRGTPRIANRLLRRVRDFAQVAGTKEIDPVLASDALDRLHVDALGLDEVDHRLLRAMVERFGGGPVGLETLAATIGEDAQTIEDVYEPYLLQQGFLQRTPRGRMITQFAKSHFGYEEEEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: VM2T3_PROMU
Sequence: MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVSALPKGAVQPKYEDAMQYEFKVNGEAVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIHNDADSTASISACDGLKGYFKLQGETYPIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRYIKLAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGMEHDDKDKCKCDTCIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNAPLRTDTVSTPVSGNEFLEAGEECDCGSPENPCCDAATCKLRPGAQCAEGLCCDQCRFKKKRTICRRARGDNPDDRCTGQSADCPRNGLYG
What is the function of this protein?
Inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_RHIEC
Sequence: MAKATKKAEAKTVTIEQIGSPIRRPDVQQRTLIGLGLNKMHRRRTLEDTPSVRGMIRAVQHLVRIVDEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TUTLB_MOUSE
Sequence: MIWYVATLIASVISTRGLVAQGAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHNALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPPGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKPQLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGGRLQATGQARPPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSSPPLHTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFPHQLHPCDVAESLQPKACLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPEPPTTLPTSG
What is the function of this protein?
Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development (By similarity).  May mediate homophilic cell adhesion (PubMed:23751499).
What are the official names of this protein?
Protein turtle homolog B, Immunoglobulin superfamily member 9B.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. Turtle family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein. Postsynaptic density.
Protein: MOAA_STAS1
Sequence: MVEQITDKLGRPIRDLRLSVTDRCNFRCDYCMPKEIFGDDFVFLPKDELLTFDEMVRIAQVYTQLGVKKIRITGGEPLLRRDLDKLIYQLNQLEGVEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDAVFQAINNRNIKASTILQQIDYAVAIGFQVKVNVVVQKGVNDDQIVPMVQYFKDKDVQIRFIEFMDVGNDNGWDFSKVVSKDEMLEMIEQNFDIEPVAPKYYGEVAKYYQHKDNKAQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFSTVDGFNVKSFMRNGATDNELFEQFKALWNIRDDRYSDERTEQTVANRKRKKINMNYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: GLYA_COXB2
Sequence: MYEPTLTVESFDSELAGAIRDERRRQEHHVELIASENYVSPRVLELQGSVLTNKYAEGYPGRRYYAGCEFVDIAEQLAIDRAKELFGADYANVQPHSGSQANAEAYMALMNPGDTLLAMDLSHGGHLTHGSPVSFSGKFYKAVHYGLNAHGDIDYEQAAQLAQEHKPKVILAGFSAFSGIVDWQRFREIADSVNAYFMTDIAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRAGLILAKANPELEKRLNSAVFPGSQGGPLMHIIAAKAVAFKEAMQPEFKTYAQQILKNAKAMAEVMKERDYTIVSGGTQNHLFLVSLLNKNISGKEAEAALGRANITVNKNTVPGETRSPFVTSGLRIGTPAITTRGFKEKEASQLAHWVCDILDDIHNEKVIADVKQKAHELCGKFPVYQELD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HYPE_BRUME
Sequence: MARHSFFCVDGHTCGNPVRLVAGGGPNLNGSTMMEKCAHFLAEYDWIRTGLMFEPRGHDMMSGSILYPPTRPDCDVAVLFIETSGCLPMCGHGTIGTVTMAIEQGLVTPKTPGKLNLDTPAGLVAIEYEQDGQYVERVRLTNVPAFLYAEGLEVECPDLGPIKVDVAYGGNFYAIVEPQENYTDMDDYSALQLIAWSPVLRQRLNEKYKFQHPELPDINRLSHILWTGKPKHPQAHARNAVFYGDKAIDRSPCGTGTSARMAQLAAKGKLKPGDEFIHESIIGSLFHGRVERAAEVAGRPAIVPSIAGWARMTGYNTIFIDDRDPFAHGFSAA
What is the function of this protein?
Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4-hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases.  Strong B-cell mitogen.  Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.
What are the official names of this protein?
4-hydroxyproline epimerase, Hydroxyproline-2-epimerase, BmHyPRE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: ACCO_DIOKA
Sequence: MESFPVINMEKMNGEERAATMGLINDACENWGFFELVNHGIPPELMDTVERVTKAHYKKCMEQRFKELVASKALEGIQAEVTDMDWESTYFLRHLPQSNISEVPDLDEEYRRVMKDFAERLEKLAEYLLDLLCENLGLEKGYLKKAFYGTKGPNFGTKVANYPPCPKADLIKGLRAHTDAGGIILLFQDDKVSGLQLLKDDQWIDVPPMKHSIVINLGDQLEVITNGKYKSVLHRVVAQTDGTRMSIASFYNPGNDAVIYPAPALVEKEVEEKEVYPKFVFDDYMKLYAALKFQAKEPRFEAMKAVEANVNLGPIATV
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RS3AB_XENLA
Sequence: MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMSREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVYARKVKMLKKPKFELGKLMELHGEGGGSGKPAADETGAKVERADGYEPPVQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May play a role during erythropoiesis (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_RHOCS
Sequence: MTDLSIAVTRLPHGADLPLPAYATEHAAGMDLLAAVAEPVILAPGERRLIPTGLAIALPDGYEAQVRPRSGLALKHGITLLNSPGTIDADYRGEVGVILANLGADPFTVERGMRIAQMVIARYARAAWDVVDSLPASARGSGGFGSTGTRG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PETD_CHLMO
Sequence: MSVTKKPDLNDPVLRAKLAKGFGHNTYGEPAWPNDLLYIFPVVIFGTFACCIGLAVLDPAAMGEPANPFATPLEILPEWYFYPVFQILRTVPNKLLGVLAMAAVPVGLLTVPFIESINKFQNPYRRPIATILFLVGTLVAVWLGIGATFPIDISLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.