PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_TERTT
Sequence: MGKIIGIDLGTTNSCVSVLEGDKAKVIENAEGDRTTPSIVAFTDDNEILVGQSAKRQAVTNPRNTLFAVKRLIGRKFTDDVVQKDIKMVPYSIVGADNGDAWVEVKGDKKAPPQISAEVLKKMKKTAEDYLGEKVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAYGMDKAKGDRTIAVYDLGGGTFDISVIEIADVDGEHQFEVLSTNGDTFLGGEDFDLRLIEYLAEEFKKSNGIDLHNDPLALQRLKEAAEKAKIELSSSQQTEVNLPYITADATGPKHLVVKLTRAKLESLVEELVNRSLEPVKMAIKDADLSVSEIDDVILVGGQTRMPLVQQKVAEFFGKEPRKDVNPDEAVAMGAAIQGAVLSGDVKDVLLLDVTPLTLGIETMGGVATPLIEKNTTIPTKKSQVFSTAEDNQTAVTIHVVQGERKQAAQNKSLGRFDLADIPPAPRGMPQVEVTFDIDANGILNVSAKDKATGKEQSIVIKASSGLSDDEIENMVKDAEANAEADRKFEELVSARNTLEGLVHATKKTLEEAGDKATAEEKSAIEAAITEAEEALKSGDKDAIEAATKKVTDASGSLAQKLYAEQSAQQQGSAGATGGEQPKADKAADDGVVDAEFEEVKDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ECFA2_STRP3
Sequence: MSINLQNVSYTYQVGTPFEGRALFNINLDILDGSYTAFIGHTGSGKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEETVLKDVAFGPQNFGISPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGILAMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVLDKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREVLKHG
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATS1_YEAST
Sequence: MSCVYAFGSNGQRQLGLGHDEDMDTPQRSVPGDDGAIVRKIACGGNHSVMLTNDGNLVGCGDNRRGELDSAQALRQVHDWRPVEVPAPVVDVACGWDTTVIVDADGRVWQRGGGCYEFTQQHVPLNSNDERIAVYGCFQNFVVVQGTRVYGWGSNTKCQLQEPKSRSLKEPVLVYDTGSVAVDYVAMGKDFMVIVDEGGRIVHASGRLPTGFELKQQQKRHNLVVLCMWTSIHLWNARLNTVESFGRGTHSQLFPQERLDFPIVGVATGSEHGILTTANQEGKSHCYNVYCWGWGEHGNCGPQKGSQPGLQLVGQYSGKPRVFGGCATTWIVL
What is the function of this protein?
Together with KTI11; associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex (PubMed:18466297, PubMed:25543256).  Association with the elongator complex is mediated via interaction with KTI11 (PubMed:18466297, PubMed:25543256).  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:25543256).  Together with KTI11; also required for diphthamide biosynthesis; diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:25543256).  May participate in regulatory interactions between microtubules and the cell cycle (PubMed:8070652).
What are the official names of this protein?
Protein KTI13, Alpha-tubulin suppressor 1, Kluyveromyces lactis toxin-insensitive protein 13.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_AXIAX
Sequence: MINLGKTSPLMKIVNNAFIDLPAPSNISSWWNFGSLLGVCLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDTLGIILLIMFLMLLVLFAPDMLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALASSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFVVIGQLASILYFLIILILMPIISSIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y828_METJA
Sequence: MRIEAEGQAKAIQIVAEAARQYFKDEAQLYKALEVANNVLKDNAKYVISENILDVVRNFIKKDKSA
What are the official names of this protein?
Uncharacterized protein MJ0828.
Protein: PRIM_HHV6U
Sequence: MTIVVFATEYDAANVIFSILCRSPSEHLIFPIIVKYKPSNNVSFCLQTQKCKNSKRIDTVFVCHAEKLNLSHYIQTASPIKAEDVANSLNDKETESLYVDMILSQTGKEREDVEFKYMAYFHKSLIIKYLTGKFLLPTSPFWFLSTYGQTEGMLLLTMFYYLFEEQKSTITTTKNYVQCFTENTGNMVFTYSSMSEFINITLKSKFRKLFADFSTYARQKNLRDKEEFKHLDTQINLFRKSSHLTNTFRVHYIYIAYNTALETTKFVNYCNLTSYDSNLPIGQQCQRNLHILGNSLHENLLCIMKQYFNADCYFKTYIDIKRLKNPNLNVTEYEYALVSKKKTIQALTSEQITRAIAKCNKNGEGLFSPVKPGLQGLLEISASDRYVQIQDKRIYRRQHLHKDYHRPFPVFRVQLLHKNIFCFGNSEDWYENMGFNRILQYLPDEYISDEALTRAIWLQDTHFLCDDVEKQFYTTRHEIFNERIPVTNYIGDLDLPLQDTATITEETFFSMCRLIRLTLINAWKKIFPSIDTDTHPIFFFKTQCDTTNDTLDYTEDPTEIKQFCVCRKKIGLRISIPLPNGTAIAGGEPLKQLSKILNHVMCLDQELSQILNSITFPGECFDIGIYHTGHCIRIGYMYKTDMDKGKMLHGRLTPIFIVPEGYRNSCKTFIQMQMDLNNLLHHGTKKAPIEELIYNITDKGCPKENLSFMDLKSRQLWNKVNIATETLITKYLNTHGFNNNATSADDSLLSFIRLIGWPIIKTQLITHYETRIAQQFSQVTFIKIDSKNLQIKKTQFGRVSDFSCLNRQHRGNRDNVLVYIQLKADGNRLILILWSTCFATKCQSNSKQVHCSIALEQLKN
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: LSG1_DANRE
Sequence: MGKKKTRGEGSGLGRALIKERLNAGRGYRRNDTWLHTSELNDGYDWGRLNLQSVTEQSSLDDFLATAELAGTEFVAEKLNIKFVPAEARAGLLSSEESRRLKKLHEENKQLLRIPRRPPWDESTSPEVLQQTEKDSFLTWRRDLARLEEEQKLILTPFERNLDFWRQLWRVIERSDVVVQIVDARNPLLFRCPDLEKYVKEVSVHKVNMLLLNKADLLTREQRRAWARYFQKEGIRAVFWSALAEAQRLEAEERGEDAMDQEDQSDTEEETASKNATDHHEENSSSPNEEKDENEQDEEEEGEDERICVDESEWQTCSEESGDEDHAEENPESTATSSFYNSSRLLRKNELLEMFKSVHSGPTCKDGQITVGLVGYPNVGKSSTINTIFRNKKVSVSATPGHTKHFQTLFVEPGLCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPAISLVCQNIPRNVLEGTYGINIIRPREDEDPDRPPTYEELLMAYGYMRGFMTAHGQPDQSRSARYVLKDYVSGKLLYCHPPPHINPEDFQPQHAKFAMRITGAEQIDGSGGKPSKVKRIENTVDKQFFHQANVRALTKGVQMVMGYKPGSGPVEAGKANTEQQAGKPWKKHGNRNKKEKVRRLNKHLDA
What is the function of this protein?
GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit.  Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity).
What are the official names of this protein?
Large subunit GTPase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. LSG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL28_PSE14
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVEGEKRFVRLRVSAKGMRIIDKRGIEVVLAELRRDGKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NCTA_ASPFU
Sequence: MTDQDSTYRPRSPDLSTFQSSIPPAVNSPIYPLASPLAHRASYDASPFFAPQYQQPPAPLGRVPQQYIPPFVDPNSPLSPDMARRSSRLARATEVAPMPEVSYAQPVLSEEPQQLPPPPPQPNPVASIEVKTKFPVARIKRIMQADEDVGKVAQVTPIAVSKALELFMISLVTKAAKEARDRNSKRVTATHLKQAVVKDEVLDFLADIIAKVPDQPAGGRKHDDDGSDQNEQPKRKRGGRRPKDDSD
What is the function of this protein?
Part of the NCT transcriptional regulatory complex that acts as a key regulator of ergosterol biosynthesis and the azole exporter cdr1B (PubMed:31969561).  The NCT complex binds the promoters of genes linked to azole susceptibility, and especially represses the expression of cdr1B transporter (PubMed:31969561).
What are the official names of this protein?
NCT transcriptional regulatory complex subunit A, Negative cofactor 2 AB.
What is the protein family that this protein belongs to?
Belongs to the NC2 alpha/DRAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTI_BACAA
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1017_STAEQ
Sequence: MVKTVYITGYKSFELNIYKDDAPEVYYLKQFIAHKLKHLLDEGLEWVLIQGQMGIELWSAEVVIELKKDFPDIKLGIITPFIGHTQRWNDKNQAKYTNIIQQADFTESIHHTEYMGAYQFKQADQFMLDHTDYTILIYDDEQEASPKYFKAMLVEFMEKTNYTCDIVTFDELTDFINDLQWSQDQSFE
What are the official names of this protein?
UPF0398 protein SERP1017.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: TBB1_ECHMU
Sequence: MREIVHIQAGQCGNQIGSKFWEVISDEHGVDPTGSYHGDSDLQLERINVYYSEASGGKYVPRCVLVDLEPGTMDSVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVESVLDVIRKECESCDCLQGFQMCHSLGGGTGSGMGTLLISKMREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSIHQLVENTDETFCIDNEALYDICFRTLKLTNPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRVLTVAELTQQMFDAKNMMAACDPRHGRYLTVAAMFRGRMSMKEVDDQMLNAQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSVTFMGNTTAIQEIFKRVSEQFTVMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEAGIGDDEEEDEEGVMGEEIDA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-tubulin 1.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PHAC_THIVI
Sequence: MRPIDIRPDKLAQEMLDYTSKLGQGMENLLNADAIDTGVSPKEAVYSEDKLVLYRYDTPAGVTPQKTPLLIVYALVNRPYMTDIQEDRSTIKGLLATGQDVYLIDWGYPDQADSALTLDDYINGYIDSCVDYLCETHEVDQVNILGICQGGAFSLMYASLHPDKVKNLVTMVTPVDFKTPGNLLSAWVQNVDIDLAVDTMGNIPGELLNWTFLSLKPFSLTGQKYVNMVDMLDDPDKVKNFLRMEKWIFDSPDQAGETFRQFTKDFYQKNGFINGGVKLGGKEIDLKNVDCPVLNIYALQDHLVPPDASKALNPWSAARTYTELAFPGGHIGIYVSGKAQKEVTPAIGKWLNERS
What is the function of this protein?
Polymerizes D(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end.  PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaC, PHA polymerase, PHB synthase subunit PhaC, Poly(3-hydroxyalkanoate) synthase subunit PhaC, PHA synthase, Polyhydroxyalkanoic acid synthase, Poly(3-hydroxybutyrate) polymerase subunit PhaC, PHB polymerase, Poly-beta-hydroxybutyrate polymerase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family. Type III PhaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPA12_MOUSE
Sequence: MELARPRSNFQSDLDFCPDCGSVLPLPGIQDTVICSRCGFSIDVRDCEGKVVKTSVVFNKLGATIPLSVDEGPELQGPVIDRRCPRCGHEGMAYHTRQMRSADEGQTVFYTCINCKFQEKEDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit H, Zinc ribbon domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TCR8_PASMD
Sequence: MNKSIIIILLITVLDAIGIGLIMPVLPTLLNEFVSENSLATHYGVLLALYATMQVIFAPILGRLSDKYGRKPILLFSLLGAALDYLLMAFSTTLWMLYIGRIIAGITGATGAVCASAMSDVTPAKNRTRYFGFLGGVFGVGLIIGPMLGGLLGDISAHMPFIFAAISHSILLILSLLFFRETQKREALVANRTPENQTASNTVTVFFKKSLYFWLATYFIIQLIGQIPATIWVLFTQYRFDWNTTSIGMSLAVLGVLHIFFQAIVAGKLAQKWGEKTTIMISMSIDMMGCLLLAWIGHVWVILPALICLAAGGMGQPALQGYLSKSVDDNAQGKLQGTLVSLTNITGIIGPLLFAFIYSYSVAYWDGLLWLMGAILYAMLLITAYFHQRKTTPKAVISTP
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein, class H, TetA(H).
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WBNH_ECOLX
Sequence: MKNVGFIVTKSEIGGAQTWVNEISNLIKEECNIFLITSEEGWLTHKDVFAGVFVIPGIKKYFDFLTLFKLRKILKENNISTLIASSANAGVYARLVRLLVDFKCIYVSHGWSCLYNGGRLKSIFCIVEKYLSLLTDVIWCVSKSDEKKAIENIGIKEPKIITVSNSVPQMPRCNNKQLQYKVLFVGRLTHPKRPELLANVISKKPQYSLHIVGGGERLESLKKQFSECENIHFLGEVNNFYNYHEYDLFSLISDSEGLPMSGLEAHTAAIPLLLSDVGGCFELIEGNGLLVENTEDDIGYKLDKIFDDYENYREQAIRASGKFVIENYASAYKSIILG
What is the function of this protein?
Involved in the assembly of the O-repeating unit during O-antigen biosynthesis.
What are the official names of this protein?
O-antigen biosynthesis glycosyltransferase WbnH, UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: XGPT_AERHH
Sequence: MPKKFYVSWDNLQREARRLARRQLPVSQWKGIIAVSRGGLVPAALMARELGIRNVETLCISSYDHNNQRDLVVVKAATTAGDGEGWLVVEDLVDTGTTAKAIRELYPKAKFIAIFAKPMGEQLLDDFEVAIPQDTWIEQPWDMALEFATPICDEE
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNH_YERP3
Sequence: MTKQVEIFTDGSCLGNPGPGGYGAILRYKQHEKTFSAGYYLTTNNRMELMAAIVALEALTSPCEVTLSTDSQYVRQGITQWIHNWKKRGWKTADRKPVRNVDLWQRLDLAIQSHTIQWEWVKGHAGHPENERCDELARQGANSPTLDDTGYNPD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_PSEA8
Sequence: MAVYNYDVVILGTGPAGEGAAMNASKYGRKLAVVDSRRVVGGNCTHLGTIPSKALRHSVKQIIEFNTNPMFRQIGEPRWFSFPDVLKSADRVISKQVASRTGYYARNRIDMFTGTASFVDERTVEVVTPSGAVERLVADQFVIATGSRPYRPSDINFNHPRVYDSDTILSLSHTPRRLIIYGAGVIGCEYASIFSGLGVLVDLIDTRDQLLSFLDDEISDALSYHLRNNNVLIRHNEEYERVEGLDNGVILHLKSGKKIKADALLWCNGRTGNTDKLGLENVGIKVNSRGQIEVDENYRTSVSNIFAAGDVIGWPSLASAAYDQGRSAAGNIVESDSWRFVNDVPTGIYTIPEISSIGKNESELTAAKIPYEVGKAFFKGMARAQISNEPVGMLKILFHRETLEILGVHCFGDQASEIVHIGQAIMNQPGELNTLKYFVNTTFNYPTMAEAYRVAAFDGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEZA_XENTR
Sequence: MTAEFDEEVVFENSPLFQYLQDLGQTDFEICPLSKEEEHLAGNGHGEQDVHTTEKKSNISRTVEFLKSWSPLFSKKKRDEKICLLENGFRLESLRTILQQEVLIQEDVELIELLDPGILSAGQTQNQQNGHLPTLWSIATPNIWEMSVLFAFLSALAALQSWSISSSLVWGPSLILFAAFTVLRALHTWRSATLRMILRKYCNQVEGTVLNSRAFTNLVRKALRLIQETEVISRGFTLLLDRVSAACPYGKAGQHASQHLLGLRKAVYRTVRTNFRISRLATLYMLKHYPLNSEIDNVTNYICVVPLKDLGLGLCEEHVSEEEAHNLTDAFSLPALKVLFQLWIGQSSEFFRRLALLLSPENAAQGHLASPEQLPHLIWSDVVQDLPHTQAACLAELKRSYEFYRYFETQHQSGFERTAKRKKEVGELSNLHGAVRSLQLHLKALLNEVIILEDELEKLSSCKEMQAMTQEASLMLEEKLRIIQPHVQASNTCWEEALCQVGRMVRRPAAKKDIEKSSCENLNFPVVSNMPPALRIEDRDPVPEEQILEAYVEEAVTDQEFNSEDIYLFSPEERERQKREREESKRVLQELKAVLGLKASEAERQKWKQLLFSEHAVITPFLPEEPVGHFEPPDSVYPEDPCKNLGFYGEFTSEINGTEHAKDTPNQGDLQMNMNHEDEAKICPLSEEAEPESGKDENESPCPVPRTVLPPAIKERLARIHQTSDLNFTSGLAAQVAARSLTFTFLQEQTFGDEWDDDDDDNDNDDDNYDQVKNVESHEKERNNVSLQLEE
What is the function of this protein?
Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life.
What are the official names of this protein?
Vezatin.
What is the protein family that this protein belongs to?
Belongs to the vezatin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Nucleus.
Protein: DNAA_BACCN
Sequence: MENIADLWNSALTELEKKVSKPSYETWLKSTKAHALKKDTLTIIAPNEFARDWLESHYSELISETIYDITGAKLNIRFIIPQSQTEEEVDYPPAKAKKMNDESNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMIYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISRLLKTDTQLQKQIEEINDILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVQW2_HUMAN
Sequence: MQYPFRKLLRPSTESCCVAQARVQWCHLGSLQPPLPGFKQFSCHSLPSSWDYRWNLTLSPRLECSGAISAHCNLCLPDLSDSPASTSRVAGTTGAHHHAQEPVVIRKM
What are the official names of this protein?
Putative uncharacterized protein CCDC28A-AS1, GVQW motif-containing protein 2.
Protein: TBA3E_HUMAN
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAREDLAALEKDCEEVGVDSVEAEAEEGEAY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-3E chain, Alpha-tubulin 3E.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SLN14_HUMAN
Sequence: MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY
What is the function of this protein?
Displays polysome-associated endoribonuclease activity towards mRNAs and rRNAs (PubMed:25996083).  May play a role in RNA surveillance pathways by recognizing stalled ribosomes and triggering endonucleolytic cleavage of aberrant mRNAs (Probable).  Cleaves different types of rRNAs and mRNAs in a magnesium- and manganese-dependent and ATP-independent manner (By similarity).  Involved in correct maturation of megakaryocytes and especially important for proplatelet extension.
What are the official names of this protein?
Protein SLFN14.
What is the protein family that this protein belongs to?
Belongs to the Schlafen family. Subgroup III subfamily.