PharMolix/UniProtQA huggingface dataset:
Protein: AGLA_THEMA
Sequence: MPSVKIGIIGAGSAVFSLRLVSDLCKTPGLSGSTVTLMDIDEERLDAILTIAKKYVEEVGADLKFEKTMNLDDVIIDADFVINTAMVGGHTYLEKVRQIGEKYGYYRGIDAQEFNMVSDYYTFSNYNQLKYFVDIARKIEKLSPKAWYLQAANPIFEGTTLVTRTVPIKAVGFCHGHYGVMEIVEKLGLEEEKVDWQVAGVNHGIWLNRFRYNGGNAYPLLDKWIEEKSKDWKPENPFNDQLSPAAIDMYRFYGVMPIGDTVRNSSWRYHRDLETKKKWYGEPWGGADSEIGWKWYQDTLGKVTEITKKVAKFIKENPSVRLSDLGSVLGKDLSEKQFVLEVEKILDPERKSGEQHIPFIDALLNDNKARFVVNIPNKGIIHGIDDDVVVEVPALVDKNGIHPEKIEPPLPDRVVKYYLRPRIMRMEMALEAFLTGDIRIIKELLYRDPRTKSDEQVEKVIEEILALPENEEMRKHYLKR
What is the function of this protein?
Alpha-glycosidase with a very broad specificity.  Hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch.  AglA is not specific with respect to the configuration at the C-4 position of its substrates because glycosidic derivatives of D-galactose are also hydrolyzed.  Does not cleave beta-glycosidic bonds.
What are the official names of this protein?
Alpha-glucosidase, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: SYA_COXBN
Sequence: MNSNQLRETFLNYFKQLDHEVVPGSSLIPENDPTLLFTNAGMVQFKDVFLGVETRPYQRAVSIQPCMRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIKFAWDFLTNVLKLPPQRLWVTVFQDDFESESIWLKEMKINPERFSRCGEKDNFWQMRDTGPCGPCTEIFYDHGPTISGGPPGSAEADGDRYVEIWNLVFMQYNRDAKGNLLPLAKPSVDTGMGLERLAAVMQGVHDNYDIDLFQYLLKALRTLLKTEDLHNTSMRVIVDHIRSVAFLIADGVIPSNEGRGYVLRRIIRRAVRHGYKLGQEEPFFYQLTKPLVEEMGGAYPLLRKSQALIEQTIKQEEIQFSNTLTKGLKILDHEMAGLPSRQIPGNLIFQLYDTYGFPPDLTADIARERDFVMDYAGFDKAMERQREQSQQAHQFVANYAQKASIGGETQFVGYETLNSQANVISLLQNDQPINRLNESEKGVVVLDRTPFYAESGGQVGDQGFLYFEKGSFRVKDTKKQGDIYLHIGEMLQGHLNVKDKVRAEVDVSRFDIMRNHSATHLLHEALRRVLGERVMQKGSLVEAKRLRFDFSHAKPLTPEELQAVERLVNQQIQANLLSTIEVMTPEEAKKKGALALFGERYGKEVRVLEMGDFSTEICGGTHTERTGEIGLFKIVSESGCAAGIRRIEALTGKAALDYIESAEQQLRSLSDLLKTNRKNLAAKLSQILEDHRKLEKELAKLKQRLASQQLESLINQVVDVHDIRTLAIRLEAVDRETLRAIVDQLKQKLGKAAIVLATIEEGRIQLVAGVTKNCLEHFNATELLAPIAEKVGGRSGGRPDLAQGAGERPENLEAALAAVPKWIEKKLKE
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_SHEWM
Sequence: MTTETLTTLEQHDRFLGRHIGPDSEQRQEMLNYVGAESLEDLTTQIVPESIRLNRDLAVGDNVSEAEGLAYIRQIADKNKVFKSYIGMGYYGTEVPSVIQRNVLENPGWYTAYTPYQPEIAQGRLEAILNFQQLSMDLTGLDLASSSLLDEATAAAEAMALAKRVSKAKKANIFFVADDVFPQTLDVIKTRAECFGMEVVVGPAEEAVNYELFGALFQYTNRYGQITDFTELFTALHEKKAIISVAADIMSLVMLKSPGSMGADVVFGNSQRFGVPMGFGGPHAAFFVSRDAHKRSLPGRIIGVSQDTRGNRALRMAMQTREQHIRREKANSNICTAQVLLANMASFYAVFHGPQGLKVIAERIHRLTDILAAGLTAKGVELVNNTWFDTLSIKGLDAKAVQKRADAAGINLRVDSCSESDGSSDQVLGVSLAETTTRTDVTQLFDVILGEGHGLDVAALDAQVMADSTSVPAELVRQDAILTHPTFNRYHSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAATEMMPITWPEFGNMHPFCPQDQAQGYAQLLGELSEWLVDITGYDAVSLQPNSGAQGEYAGLLAIKQYHESRGDAHRNICLIPSSAHGTNPASAQLAGMKIVVTACDKAGNIDMEDLKAKAAEVADNLSCIMVTYPSTHGVYEETIGEICEVIHQHGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKKHLAPFLSGHSVVKHGLESDGNGAVSAAPYGSAGILPITWMYIKLLGKQGLRESTQVALLNANYMMKKLSEHYPVLYTGRNDRVAHECIIDLRPLKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIEAMVSIRAEAARVESGEWPVDNNPLHNAPHTLADIMDPEFDSRPYSREVAVFPTAAVKQNKFWPTVNRIDDVYGDRNLFCACVPISDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: REPA2_BUCAP
Sequence: MPRKNYICNLKPVFNPPKNEKKRSNFIDYAMKKASEIDVARSKLNYTLLAIDPKTGNILPRFRRLNEHRACAMRAIVLAMLYYWNTNSNLVEASIEKLSDECGLSTFSNSGNKSITRASRLITDFMEPMGFIKCKRKKTQSSSNYIPKKIFLTSNFFMLFHISQSTINQYLSEQKQSIKNLKKEKKIFISFSDIRVISKLDEKAARNKILNALIKYYSASELTKIGPQGLKKKIDIEYSNLCKLYKKNNK
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.
What are the official names of this protein?
Probable replication-associated protein repA2.
What is the protein family that this protein belongs to?
Belongs to the IncFII RepA family.
Protein: IHFA_PSYIN
Sequence: MALTKAEIAADLSVKIGLSKREAKEFVESFFEEIKATLENGEAVKISGFGGFELKDKSERPGRNPKTGEDIPIAARRVVTFRAGQKLKELVEKNMPDTEV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MUKF_SALCH
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RL28_DEIRA
Sequence: MSRECYLTGKKNLVVNSVIRRGKARADGGVGRKTTGITKRVQRANLHKKAIRENGQVKTVWLSANALRTLSKGPYKGIELI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GPMA_PORG3
Sequence: MKRIVLIRHGESLWNKENRFTGWTDVDLSEKGIEEAKKAGELMKKEGFQFTKAYTSYLKRAVKTLNGVLDVMDLDWIPVEKTWRLNEKHYGMLQGLNKAETAEKYGDEQVLIWRRSYDVPPTPMEKEDPRSPFMDPRYKGVCEKDLPLTEALCDTVNRILPYWNETIFPTLKEHDEVLVAAHGNSLRGIIKVLKNISDEDIISLNLPTAVPYVFEFDDNLRLVKDYFLGDPEEIKKLMEAVANQGKKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ENOX1_MOUSE
Sequence: MVDAAGFESVAQCPRELHQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLADKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLAIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT
What is the function of this protein?
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface.  Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement.  The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock (By similarity).
What are the official names of this protein?
Ecto-NOX disulfide-thiol exchanger 1, Constitutive Ecto-NOX, cNOX.
What is the protein family that this protein belongs to?
Belongs to the ENOX family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Extracellular and plasma membrane-associated.
Protein: RUVC_CHLFF
Sequence: MTQLIMGIDPGTLVSGYAIILVEQRYKIRAHSYGAIRLSSKDSLTQRYKQLFQTISGVLNDITPDAVVLETQYVHKNPQSTIKLGMARGVLVLAAALRDIPVFEYAPNVAKRAVVGRGNASKQQVQLMVSKMLNIPDVLNANCEDIADAFALAICHAHTSSYDFLGVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TES_ATEGE
Sequence: MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVHNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQIYIPGGDRSTPPAVGAMEDKSAEHKSTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSICHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVSDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: DEOC_STRP8
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEATKPDSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4158_STRCO
Sequence: MAKVTRDDVARLAGTSTAVVSYVINNGPRPVAPATRERVLAAIKELGYRPDRVAQAMASRRTDLIGLIVPDARQPFFAEMAHAVEWAASERGKMVLVGNSDYVGEREVHYLRAFLGMRVSGLILVSHALNDNAAAEIDAWDARVVLLHERPEAIDDVAVVTDDLGGAQLAVRHLLEHGYAYVACMGGTAETPSVGDPVSDHVEGWRRAMKEAGLSTEGRLFEAPYNRYDAYRVGLELLSGPQRPPAIFCSTDDQAIGLLRAARELRIDVPGELAVAGFDDIKEADLADPPLTTVASDRSAMARSAVDLVLDDGLRVAGSRRERLKVFPSQLVVRQSCGCA
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator SCO4158.
Protein: 079R_FRG3G
Sequence: MLDMRSMVTVHPALIAKPKGKTVSGDGADPKKRGRPKKNATEPAVRNPVTRAGVTRYMNPLVESLVRDNPFRGDNLVKESLLGQTLAEQTLVRANSRDNLLKESLVEQSFVDQTLQDQSLVDQSILRESLLRDNPRDTLRKESLRKYNSRANPLAESLLEESTTPKPRRGAHRKPLVLTKEMEEKLEALDRDMRTAEETKVSIAGSAGIPVTALPGMEALGVMQMVSSLGFLDAGDKPNVIKTMVVKYLDVFLSMGCSAPKPCLVNVPRGYRRFKQSSSVSPAYAAKLSSEDTEAWSGAAGVAVEAKMRHTAAVLESRNLSLEPYGSNPIKLERSALAAYMELMSMAEEAEGEDLEGIISDCRVLRTSTEWCRDLSQTVSSWWPPLREAISRRGTALSDYVSDREVDVIRGRSRVPALSCVLLYGKRVDDNDAPLTAPQTVLKPFDVTDYSRRLGGVWLHHARFPEYAPKRLFDPRPGAEPVLIRTCAGYLMTEERGPLRCWRKDAHMYQISLEIYNRLTTELNAVPPQTRCGRYNAKWLSTNGPTGVQKIVLAAARALTEPRLSWNDVFEV
What are the official names of this protein?
Uncharacterized protein 079R.
Protein: TYSY_BREBN
Sequence: MKQYLDLCQRILDEGVIKEDRTGTGTTSVFGHQMRFDLSEGFPMVTTKKLHMKSIIHELLWFLSGDTNVRYLQENGVRIWNEWADENGDLGPVYGSQWRSFTGRDGKTVDQIQWVIDEIKRNPDSRRLIVSAWNPAELDKMALPPCHLLFQFYVANGKLSCQLYQRSGDTFLGVPFNIASYALLTHMVAHVTGLEVGDFVHTIGDAHLYLNHIEQVKLQLTREPKPLPKLVLNPDVTSIFDFKYEDIEIVGYESHPHIKGEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_MAGMM
Sequence: MSSDKKQGFEASLERLEALVGELERGELPLEEALAAYEEGMKLARLCQKRLDSAEKRIEKIATPSGDEEA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA69_PAPAN
Sequence: MWTEEAAATAEARESGIRNKSSSSSQIPVVGVVTEDNEAQGVFKPMDLNRVIKLLEETDKDGLEEKQLKFVKKLVQCFQNGLPLRDLAQIFKILNLCAGKIKNQPRFVESAYDIIKLCSLPFLKKKVSDEITYAEDTANSIALLGDLMKIPSSELRIQICKCIVDFYHAEPPKKHIPGYQQASSSYKIQMAEVGGLAKTMVQSITLLEHQLVEKLWVLKVLQHLSTSEVNCTIMMKAQAASGICTHLNDPDPSGQLLFRSSEILWNLLEKSSKEEVIQQLSNLECLLALKEVFTNLFMRGFSHYDRQLRNDILVITTIIAQNPEAPMIECGFTKDLILFATFNEVKSQNLLVKGLKLSNSYEDFELKKLLFNVIVILCKDLPTVQLLIDGKVILALFTYVKKPEKQKIMGWSAAQHEELQLHAIATLSSVAPLLIEEYMSCQGNARVLAFLEWCESEDPFFSHGNSFHGTGGRGNKFAQMRYSLRLLRAMVYLEDETVNTDLCEKGTIQQMIGIFKNIISKPNEKEEAIVLEIQSDILLILSGLCENHIQRKEIFGTEGVDIVLHVMKTDPRKLQSGLGYNLLLFSTLDSIWCCILGCYPSEDYFLEREGIFLLLDVLALNQKKFCNLILGIMVEFCDNPKTAAHVNAWQGKKDQTAASLLIKLWRKEEKELGVKRDKNGKIIDTKKPLFTSFQEEHKIIPLPANCPSIAVMDVSENIRAKIYAILGKLDFENLPGLSAEDFVTLCVIHRYLDFKIGEIWNEIYEEIKLEKLRPVTIDKKALEAITTASENVGKMVASLQSEIIESQARQDVQNEQKVYAKIQATHKQRELANKSWENFLARTSNAKTLKKAKRLQEKAIEASRYHKRPQNAVFHGTDIKGLNTTVPSGGVVTVESTPARLVGGPLADTDIALKKLPIRGGALQRVKAVEIVDAPKKSIPT
What is the function of this protein?
Cilium- and flagellum-associated protein (By similarity).  In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity).  Required for sperm flagellum assembly and stability (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 69.
What are the subcellular locations of this protein?
Cell projection, cilium. Cell projection, cilium, flagellum. Note=Localizes to the midpiece of the sperm flagellum.
Protein: THII_SALEP
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALAQYREQLEGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAIKAKIEAEEENFDFSILDKVVEEANNVDIREIAQQTQQEVVEVETVSGFGPNDVILDIRSVDEQDDKPLKVEGVDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFENVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRG1_MOUSE
Sequence: MMKSVVLVILGLTLLLETQAMPSSRLSCYRKLLKDRNCHNLPEGRADLKLIDANVQHHFWDGKGCEMICYCNFSELLCCPKDVFFGPKISFVIPCNNH
What are the official names of this protein?
Scrapie-responsive protein 1, Scrapie-responsive gene 1 protein, ScRG-1.
What is the protein family that this protein belongs to?
Belongs to the SCRG1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: WALR_STAAW
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins (By similarity).  Functions as a transcription regulator by direct binding to promoter regions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSHC_BACCQ
Sequence: MEIKEISVPQQGVVADYMNGEKEIQSCFDYMLTEDAFKQRVQDLREREFFRQDLVAHLLEYNTKLQAGEATIQNVKALEDEDTYVVIAGQQAGLLTGPLYTIHKIISVLQLAKEKEESLGVKVVPVFWIAGEDHDMDEINHTFVTKNKKIKKTIFHDRNPKKASASESELSLEDCRKWIEEIFKTYPETNFTKDVLRFIDDSLGKSNTYVDFFGHLIMKMFINSGLILVDSHHPELRKLEVPFFKQIVSKYKEVQEGLHNQQEVIKELGYKPIIETKSNAVHIFMEIDNERVLLEDNQGKFVGKDGTYSFSYEELIEEMERSPERFSNNVVTRPLMQEYVFPTLAFIGGPGELAYWSELQQVFHTIGFRMPPVVPRITITYIERDIATDLHDLQLQESDPFLNNVDKLRENWLSNQIEEPIDERFVEAKKEIIDIHKSLQQFVKKIDPGLSSFAGKNEFKINEQIELLERMLKRNIEKKHEVELNKFRRIQFAIRPLGAPQERVWNVCYYLNQFGLDFVDRVMEKPFSWNGKHHVIKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: NUOCD_ECO24
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ICP27_EHV1K
Sequence: MALSSVSSCEPMEDEMSIMGSDTEDNFTGGDTCAEATRGLVNKSAFVPTQTVGTVSALRNVVGNPPKSVVVSFSASPQRAQPSNPKSERPAFGHGRRNRRRPFRRNNWKQQQRGWEKPEPENVPARQSAGSWPKRSSLPVHMRLGQRGGDSSSADSGHGGAGPSDRWRFKTRTQSVARVHRNRRRGNANHGSNTPGRSAGDRLNAAAARSIADVCRRVTSSRIGEMFHGARETLTTPVKNGGFRAENSSPWAPVLGFGSDQFNPEARRITWDTLVEHGVNLYKLFEVRSHAAEAARSLRDAVMRGENLLEALASADETLSWCKMIVTKNLPMRTRDPIISSSVALLDNLRLKLEPFMRCYLSSSGSPTLAELCDHQRLSDVACVPTFMFVMLARIARAVGSGAETVSRDALGPDGRVLADYVPGACLAGTLEAIDAHKRRCKADTCSLVSAYTLVPVYLHGKYFYCNQIF
What is the function of this protein?
Multifunctional regulator of the expression of viral genes that mediates nuclear export of viral intronless mRNAs.  This immediate early (EI) protein promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP (By similarity).
What are the official names of this protein?
mRNA export factor ICP27 homolog, Transcriptional regulator IE63 homolog.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: Y384_CLOB6
Sequence: MRIGFDHEKYLEEQSKYILERVNNYDKLYLEFGGKLLFDLHAKRVLPGFDENAKIKLLHKLKEKVEIIICLYAGDIERNKIRGDFGITYDVDVLRLIDDLRGYDLEVNSVVITRYSGQPATNIFINKLERRGIKVYKHEATKGYPTDVDTIVSDEGYGKNPYIETTKPIVVVTAPGPGSGKLATCLSQLYHEYKRGNVAGYSKFETFPVWNVPLKHPLNIAYESATVDLKDVNMIDSFHFDAYNKVAVNYNRDIESFPVLKRIIEKITGEESVYKSPTDMGVNRVGFGIVDDEVVKEASKQEIIRRAFKTACEYKKGYVDKETFHRAKLIMEEMNLKEEDRKVVIPAREYAAKLKERANKSETCTVVALELEDGTILTGRSSELMDGTAAVILNAVKHYANISDEIHLISPVILEPIINLKAKTLGSKRTALSCEEVLIALSICAATNPTAQVAMGRLPMLKGCQAHSTTILSTNEEQTFRKLGIDVTCDPEYISESLYYNN
What are the official names of this protein?
UPF0371 protein CLJ_B0384.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: POL_MLVRK
Sequence: LEILAETHGTRPDLTDQPIPDADHTWYTDGSSFLQEGQRKAGAAVTTETEVIWARALPAGTSAQRAELIALTQALKMAEGKRLNVYTDSRYAFATAHIHGEIYKRRGLLTSEGREIKNKSEILALLKALFLPKRLSIIHCLGHQKGDSAEARGNRLADQAAREAAIKAPPDTSTLLIEDSTPYTPAYFHYTETDLKKLRELGATYNQSQGYWVFQGKPVMPDQFVFELLDSLHRLTHLGYQKMKALLDRGESPYYMLNRDKTLQYVADSCTVCAQVNASKAKIGAGVRVRGHRPGTHWEIDFTEVKPGLYGYKYLLVFVDTFSGWVEAFPTKHETAKIVTKKLLEEIFPRFGMPQVLGTDNGPAFVSQVSQSVAKLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTLATGTRDWVLLLPLALYRARNTPGPHGLTPYEILYGAPPPLVNFHDPEMSKFTNSPSLQAHLQALQAVQREVWKPLAAAYQDQLDQPVIPHPFRVGDTVWVRRHQTKNLEPRWKGPYTVLLTTPTALKVDGISAWIHAAHVKAATTPPIRPSWRVQRSQNPLKIRLTRGAP
What is the function of this protein?
During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme.  RNase H activity is associated with the reverse transcriptase.
What are the official names of this protein?
Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.