PharMolix/UniProtQA huggingface dataset:
Protein: GTAJ_DICDI
Sequence: MTSMSTAATIKLPYQQQQHHLINSNNSYIQQQQQSPQQHHQQSVNINNCNNNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNNNKQIPQQSIQTHANSILQLNKTMPHVNPPQQNHIMNQQQQQQQQQHYQQQQHPHQQQHPHQQQHPHQQQHPHQQQHPHQQQIQQQQQQQQQQQQQQQQQQQQQQQQQQPQQQQPQTQSTQERKWDEIKIYSDLIKRFALEASHLTISKENYDDLYNMAFCLFKTVDSMDPDKMPMNMGGNSRKNSFDMYNNNNNNNNNNNINNNNNNNNNNNINNNNNNNNNNNNNNNIVYNPYGNDGPTIPSPHLQHQQQHQQQQHQQQHQQQHQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQYHNGMPHHMQQHSPESMDHQRIVKLPTGNQNNNYSNDYYSIQAVHSPHLGPSMHLQQQQQNQQNQQIQQQHQQIQHQQQYSQLPIEQQQQMMLQQQQQQQQQQQQQQQQQQQQQQLQQQQHHQQQQIQQQQQSIAKQQMPQQQNTPNNGSPSSSDGKSPVNSNTAITSNNNNNNNNNNNNNNNNNNNSTTPVADPQKNFSGEVFFDDIGQDKPQRRRRRTMYSSRRNLKCHYCEVTETPEWRRGPDGDHTLCNACGLHYAKSQKKLAREKELEKQKELEREKERENTRKHSIDFMLMNDTSSAPTNSQNPTPN
What are the official names of this protein?
GATA zinc finger domain-containing protein 10.
Protein: RSBW_STAAU
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKEPGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: SYY_METAC
Sequence: MDRLELIRRNVQEIVTEEELEGLLKNKEAPRAYVGYEPSGKIHMGHVLTVNKLIDLQKAGFKITVLLADVHAYLNKKGTLEEVRKIADYNRRCFIALGLDEEQTDFVYGSDFQLGAEYMLNVLKLSRAVTLNRAKRSMDEVGRAMDDPTVSQMVYPLMQAIDIALLEVDVAVGGIDQRKIHMLARENLKSLGFETPICIHTPILLGLDGTKMASSKDNFISIDDTGEDIYRKFKKAFCKIGDVEENPILALFRYHIFPRYETVVIERPEKFGGDITYHSYAEMESNFIEEKVHPMDLKNAAAKYINEILDPVRKVLL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_PORGI
Sequence: MLLGMSLEELTTVALRMGMPRFAGKQLAEWIYVRRATDFAEMTNISQANRQKLAEIYDLGRYPWSDVQCSVDGTKKYLFPVGEGRFVESVLIPEGDRATLCISSQVGCKMDCLFCMTGKQGWNGNLSAAEILNQIFSVDEAAELTNLVYMGMGEPLDNTDEVLRSIEALTEPWGMGWSPKRITVSTIGAKGLERFLAESRCHLAVSLHSPFPEERRKLMPGEKAFPIMQTLDRIRAYDFSGQRRVSFEYIVFDGLNDDMRHADELAAILRGIPCRINLIRFHKIPAVSLRSSDTARMEAFRKRMESHGFTCTIRASRGEDIFAACGMLSTSKAESSEEKSS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX16_ARATH
Sequence: MEAYKQWVWRNREYVQSFGSFANGLTWLLPEKFSASEIGPEAVTAFLGIFSTINEHIIENAPTPRGHVGSSGNDPSLSYPLLIAILKDLETVVEVAAEHFYGDKKWNYIILTEAMKAVIRLALFRNSGYKMLLQGGETPNEEKDSNQSESQNRAGNSGRNLGPHGLGNQNHHNPWNLEGRAMSALSSFGQNARTTTSSTPGWSRRIQHQQAVIEPPMIKERRRTMSELLTEKGVNGALFAIGEVLYITRPLIYVLFIRKYGVRSWIPWAISLSVDTLGMGLLANSKWWGEKSKQVHFSGPEKDELRRRKLIWALYLMRDPFFTKYTRQKLESSQKKLELIPLIGFLTEKIVELLEGAQSRYTYISGS
What is the function of this protein?
Involved in the formation of peroxisomes, lipid bodies and protein bodies.
What are the official names of this protein?
Peroxisome biogenesis protein 16, Peroxin-16, AtPEX16, AtPex16p, Protein SHRUNKEN SEED 1.
What is the protein family that this protein belongs to?
Belongs to the peroxin-16 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Moves through an intermediate compartment from endoplasmic reticulum to pre- existing peroxisomes.
Protein: PLSX_CERS4
Sequence: MASETAFQATGAGRIVISVDAMGGDRGPAAVVAGLAESASAIPGAYFIVHGDEAHLGPMIAKRKDLKGRCEIRHAPRVVTMNDKPSQVMRHGEGTSMWSCIESVRAGEATVAVSCGNTGALMAVSMIRLRKLPGVNRPAIACMWPSRNPGGFNVMLDVGADIKADAEDLAQYALMGASYARNGLSLERPRVGLLNVGTEEHKGRAELKVAQDLISANAAAGAYEFVGFIEGGDIPGRRCDVIVTDGFTGNVALKTGEGTAKLISDFLREAFGANILSKMAAVLALGSLKRLQKRIDPRRVNGGVFLGLNGTVVKSHGSADGTGVAAAIALAARLAQSGFHERLAARLASAGRAGQDAPDEMAAPGRSEKR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TP8L2_HUMAN
Sequence: MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAIKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits JUN/AP1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2, Inflammation factor protein 20.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: RPOZ_PROMM
Sequence: MITSGVEPKDLAKRGESLIRQSSNRYLTTVRIAFRAKQRRFDDFDGLLEESSVKPVQRAIVELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CH36_CERCA
Sequence: MNCFLFTLFFVAAPLATASYGSSSGGGGGGSSYLSSASSNGLDELVQAAAGGAQQAGGTITPANAEIPVSPAEVARLNQVQAQLQALNSNPVYRNLKNSDAIAESLAESSLASKIRQGNINIVAPNVIDQGVYRSLLVPSGQNNHQVIATQPLPPIIVNQPALPPTQIGGGPAAVVKAAPVIYKIKPSVIYQQEVINKVPTPLSLNPVYVKVYKPGKKIDAPLVPGVQQNYQAPSYGGSSYSAPAASYEPAPAPSYSAAPAQSYNAAPAPSYSAAPAASYGAAPSASYDAAPAASYGAESSYGSPQSSSSYGSAPPASGY
What is the function of this protein?
Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
What are the official names of this protein?
Chorion protein S36.
What is the protein family that this protein belongs to?
Belongs to the chorion protein S36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS8E_METST
Sequence: MAIWQGSSLRKPSGARSRRNKNKRNAEFGRNPAETRIGDEVKKEIVARGNCTKTRATVAKRINVIDPKDNSSKNVEMLTVLENGANSHFVRRNIITKGAIVETEIGKAKITSRPGQKGIVNGVLIE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: SART3_PONAB
Sequence: MATAAATSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPGWDQQEEGVSESDGDEYAMASSAESSPGEYEWEYDEEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAQDGLDREHVYDLFEKAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALWEAYREFESAIVEAARPVAGFLSPFDREQTFDSQLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDEEEQPSKRRRVENSIPAAGETQNVEVAPGPAGKCAAVDVEPPSKQKEKAASLKRDMPKVLHDSSKDSITVFVSNLPYSMQEPDAKLRPLFEACGEVVQIRPIFSNRGDFRGYRYVEFKEEKSALQALEMDRKSVEGRPMFVSPCVDKSKNPDFKVFRYSTSLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENVIKVAISNPPQRKVPEKPETRKAPGGPTLLPQTYGARGKGRTQLSLLPRALQRPGAAAPQAENGPAAAPAVAAPAATEAPKMSNADFAKLFLRK
What is the function of this protein?
U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery.  Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation.  Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex.  The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites.  May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15.  Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly.  May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair.  May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC.
What are the official names of this protein?
Squamous cell carcinoma antigen recognized by T-cells 3, SART-3.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus speckle. Cytoplasm.
Protein: TIG_NITMU
Sequence: MQTNVENLGALERRLNVSVPQEKIETEVESRLKRLARTAKFHGFRPGKVPLKIVAQQYGPQVRQEVMEDVLKKNFSEAVRENNLRVAGYPRFEPKLAESDTAQVEFSATFEVYPDITLGDLGGAHIERPVVEVTPADVDKTLEVLRKQRVEFEPVDRPAQAGDRINIDYRGLIDGAEFAGGKAENFSLVLGEGRLLKDFEEPLLGMSPGQSKTFEVAFPSDYHGKEVAGKTAVFEVKLSGVESSKLPEVNADFATSLGIAEGDVEKMRSEIRANLEREAAKRVNARLKEQVMQVLIDTTSNIDPPKALVEMELDRLMEDARNDFASRGLDTKNFSLPHDMLQERAQHRVKLGLILGELVKMHNLHPKPEQVRAVVEDLAQAYENPAEVVSWHYAAPERLREAESAALEDNVVTWVLEKAVVTGKPMPLDELMGRS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS8_STRA3
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIADILKREGFVKNVEVIEDDKQGIIRVFLKYGQNGERVITNLKRISKPGLRVYTKHEDMPKVLNGLGIAIVSTSEGLLTDKEARQKNVGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RNH_SALHS
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_BURCM
Sequence: MRIALGVQYDGAAFCGWQAQPHGKTVQDALERALGEFACVPLHTTVAGRTDTGVHGLGQVVHFDTDLDRTDFSWVRGTNAFLPSTVSVQWAKPMPETFHARFAAFERTYYYVLYVHPVRSPMLAGRAGWIHTPLDDDAMRAAAAHLIGEHDFSSFRSSECQSKTPVKHLYQIDVRRSGHFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPADWLADVLAGRDRTLAAPTFMADGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDLPS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PCNA_ORYSJ
Sequence: MLELRLVQGSLLKKVLEAIRELVTDANFDCSGTGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNLSMGMNLNNMAKMLRCAGNDDIITIKADDGSDTVTFMFESPNQDKIADFEMKLMDIDSEHLGIPDSEYQAIVRMPSSEFSRICKDLSSIGDTVIISVTKEGVKFSTAGDIGTANIVCRQNKTVDKPEDATIIEMQEPVSLTFALRYMNSFTKASPLSEQVTISLSSELPVVVEYKIAEMGYIRFYLAPKIEEDEEMKS
What is the function of this protein?
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
What are the official names of this protein?
Proliferating cell nuclear antigen, OsPCNA, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPH_XANCB
Sequence: MDVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVSQAVRVEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGQIYLVEDIEQVATLQVRQPENLAYTTQTTLSVDDTMGIIEALRVRYPAMQGPKHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRDGVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGANGVSELAGEPESMVFALPKELRLRLVS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PLSX_BACHK
Sequence: MKIAIDAMGGDHAPKAVVLGAMKAIKEYSDLHITLVGKEEEIRQYLTSEERITILHTDEKIESTDEPVRAVRRKKQASMVLAAQQVKDGVADACISAGSTGALMAAGLFVVGRMEGIERPALSPTMPTVDGEGFVMLDVGANVDAKPIHLYQYAVMGSVYAEKVRGIKNPRVGLLNVGTEDGKGNELSKQVFTMLKDAPINFVGNVESRDLLQGVADVVVCDGFTGNVALKSLEGTALALFSMLKEQLMSSFTSKLAAAVLKPKLMVLKDKMDYSEYGGAALFGLKAPVIKAHGSSNDQSIFSAIRQTREMVAKEVIPTISSVMEKEPLQ
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SYC_ECO7I
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_THEYD
Sequence: MRSDSIKKGLERTPHRALLFATGIPKSEMNKPFIGVATSFTDIIPGHISMKELERFIEKGIHTGGGYPFFFGIPGICDGIAMGHKGMKYSLPSRELIADIIECIVEAHQFDGIVLLTNCDKITPGMLMAAARLDIPAIVLTAGPMLAGYYKGQRRNLTSDTFEAIGKFKKGVLTEKDLEALELCACPGAGSCQGMYTANTMACVTEALGMSLPGTAATPAVMSEKRRLAFETGVKIVELVRKKINARQILTKEAFYNAIAVDMALGGSTNTVLHIKAIANEAGINLPLEVFDEISRKTPHLVNIIPSGEHYMEDLYKAGGIPAVLKRLKDKIYSNPTVSGIDIKEIAQKAEIYDENVIRSIKKAYHKEGGVAILKGNLAPDGAVVKQTAVSSKMLKFEGIARCFDSEENAMKAILDGKIKEGDVIIIRYEGPSGGPGMREMLSPTSAITGMGLNESVALITDGRFSGGTRGPCIGHVSPEAARGGPIAIVKDGDKILIDIPKRKIEILISESEIKKRLKNWKPPKQKIEKGYLLRYARNVSSADKGAILE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RND_SERP5
Sequence: MNYQLITTDAGLQQVCDQAKKHAQIALDTEFVRTRTYYPQLGLIQLYDGEQLSLIDPLPIKQWQPFIELLSNTQVVKFLHAGSEDLEVFLNAFKTLPTPMVDTQILAAFTGRPMSCGFATLVAEYMEVELDKSEARTDWLARPLTEKQCVYAAADVFYLLPMAKRLVQETEEAGWTAAASNECLLLCQRRSETLAPELAYREITNAWQLRPRQLGCLQKLAEWRLRQARERDLAVNFVVREENLWQVARHMPTSLGELDSLGLSGPEIRYHGKTLVALVAEAAELEESALPEPLPNLIDQPGYKKVFKEIKAAIVIASEQSGLSSELLASRRQINQLLNWHWKLKVGDNLPELVSGWRGDLLAAPLQDILKGY
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_RIPO1
Sequence: MSDNLRSRIVTQGSQRTPNRAMLRAVGFGDNDFIKPIVGVANGYSTITPCNMGLNDLALRAEAGLKSAGAMPQMFGTITISDGISMGTEGMKYSLVSREVIADSIETACNGQSMDGVIAIGGCDKNMPGAMIAIARMNIPAIFVYGGTIKPGHYQGEDLTVVSAFEAVGKYSAGKIDDNELLAIERNACPGAGSCGGMFTANTMSSAFEAMGMSLPYSSTMAAEDAEKADSTEQSAFVLVEAIRKQILPSQILTRKAFENAIAVIMAVGGSTNAVLHLLAIANTMGVELTIDDFETIRKKVPVLCDLKPSGRYVTVNLHQAGGIPQVMKMLLNHGLLHGDALTISGQTIAEVLQDIPDEPPANQDVIRPWNNPVYPEGHLAILKGNLAAEGAVAKISGVKKPKMTGPARVFESEEACLDAILAGKISAGDVVIVRYEGPKGGPGMREMLAPTSAIIGAGLGDSVGLITDGRFSGGTYGLVVGHVAPEAFVGGTIALVNEGDSVTIDAEKRLLQLNVSDEELATRRAHWTPPKPRYQRGILGKYAKLVSSSSLGAVTDVELF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MSRB_STAA3
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MRAY_PARP8
Sequence: MLLALAQWLQNDVGFLRVFSYLTFRAVAATITALLIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVSTLLWADLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSLIGLFAAVYLAFSVSEASNVRVFDLFMAWVRSGLSMGLPARADLLLPFLKSMTYPLGVWGFIALTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSSLGVFAYVMGSAVYSKYLLFPHIAGAGEMLIFCSAMGGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGIFVAETVSVMLQVTWFKFTKARFGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CWC15_DEBHA
Sequence: MTTNHRPTLESKRGKAESISNTIFHSRSLPQHTSLKYRGDIRKPKVDTKIGKQAVEELKKDLLLNEGKLEDSLKINKSLTDGDHSMDEHISKTIDNQEDERDYNRQEYDERSIGKEEYSGSEDDSGDDSEDETAQLMEELAKIKKERQEEQEKLELQNKLDKTKVSNPLVQVVGASTEANFKIKKSWRDSTAFKKQNSQNKNDDETFTNDTLNSEFHQNFLTKYIR
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC15.
What is the protein family that this protein belongs to?
Belongs to the CWC15 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIP_CHLMU
Sequence: MKNILSWMLMFAVALPILGCDNNGGSQTSAMGKDMVEDSVLTDNQKLSRTFGHLLARQLSSTEDFTLDLTEVIKGMQSEIEGKSAPLTDSEYETQMALVQKASFEKKCSENLASAEKFLKENKDKEGVIELEPNKLQYRIVKEGTGRVLTGKPNALLHYTGSFINGKVFDTSEKNKDPILLPLTKVISGFSQGMQGMREGEVRVLYIHPDLAYGTSGQLPPNSLLIFEVKLIEANDDNVSVAE
What is the function of this protein?
PPIases accelerate the folding of proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase Mip, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: AMP2_PARCM
Sequence: MGAAKVLLVVLAVMVAVPNLAEGRSPPQCQYTNCAAVLCPAVYCANAYTPPCGCCDICPPQKYGGGYRPRG
What is the function of this protein?
Has antibacterial activity, mainly against marine Gram-positive bacteria like C. maltaromaticum (MIC=50 uM), C. mobile (MIC=50 uM), C. divergens (MIC=50 uM) and C. funditum (MIC=25 uM) but also against C. glutamicum (MIC=12. 5 uM).  Has very little or no activity against Gram-negative bacteria.
What are the official names of this protein?
Paralithocin 2, P30.
What is the protein family that this protein belongs to?
Belongs to the paralithocin family.
Protein: Z780A_HUMAN
Sequence: MVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLISLGSSISKPDVITLLEQEKEPWMVVRKETSRRYPDLELKYGPEKVSPENDTSEVNLPKQVIKQISTTLGIEAFYFRNDSEYRQFEGLQGYQEGNINQKMISYEKLPTHTPHASLICNTHKPYECKECGKYFSRSANLIQHQSIHTGEKPFECKECGKAFRLHIQFTRHQKFHTGEKPFECNECGKAFSLLTLLNRHKNIHTGEKLFECKECGKSFNRSSNLVQHQSIHSGVKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCKECGMAFRYHYQLIEHCQIHTGEKPFECKECGKAFTLLTKLVRHQKIHTGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLVQHQSIHAGIKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCRECEMAFRYHCQLIEHSRIHTGDKPFECQDCGKAFNRGSSLVQHQSIHTGEKPYECKECGKAFRLYLQLSQHQKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKLHTGEKPFECKECGKAFRLHMQLIRHQKLHTGEKPFECKECGKVFSLPTQLNRHKNIHTGEKAS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 780A.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.