PharMolix/UniProtQA huggingface dataset:
Protein: 5DNU_ECO7I
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOOK_DROSI
Sequence: MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWLSKIKASAVGSNWRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELERLLQLVLGCAVNCAEKQSYITEIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRGSRTGLLDSKAVQEDRDALAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVIGDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIEELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEFDNKNLEGKNLALQRAKDSLLKERDNLREAVDELKCGQLSSSTALTGTTVSRELQPSATVEKLQRLEAENKALREGQGGQTALAQLLDDANKRCENLREQLKTANERILSLSHASQSDDPILKESEFGKQIKQLMELNEQKTLQLEEAVTQSTSLQCKVTQLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDPRIASALDASVLEKSADLVEEEPKPKMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAILMGSGQTFLARQRQSAPRKSLSAMKSK
What is the function of this protein?
Involved in endocytic trafficking by stabilizing organelles of the endocytic pathway.  Probably acts as a cytoskeletal linker protein required to tether endosome vesicles to the cytoskeleton.  Involved in modulation of endocytosis at stages required for down-regulation of membrane proteins that control synapse size.  Not involved in synaptic vesicle recycling.  Required in R7 cells for boss endocytosis into multivesicular bodies (MVBs).  Has a role in regulating adult longevity.
What are the official names of this protein?
Protein hook.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Synapse. Note=Enriched at neuromuscular synapses, in both presynaptic and postsynaptic regions.
Protein: RS19_BORHD
Sequence: MARSIKKGPFIEKSLYQKVLASSGREKRVVIKTYSRASTIIPEMVSLTISVYNGKSFIPVYITEDLVGHKLGEFSPTRIFRGHAKSDKKGRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL18_LISW6
Sequence: MITKIDKNKVRKKRHARVRSKISGTESRPRLNVFRSNKNIYAQIIDDVNGVTLASASNLDKDFGSAESKVDAASKVGELVAKRASEKGITSVTFDRGGYLYHGRVKALAEAARENGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TRMN6_ECOSM
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG9_USTMA
Sequence: MDRDSPFADPDRSDPLPAPSNTLKASIFAQSRIVHPSTSVYNQFGRHRHDDIGQESFHEGIQPSVASLANLQGSYTAKSIHPHHSAIGLRNSSYDDHGDDADEQDPEDLLSDEELGLIAGDARNPSASLSYASNRSRKRRTNPSDPRSRASAVGGLSAKQKALWMWANVDNLDAFLQEVYAYYVGRGAICIALSRSLNLLTVAFVICFSTFLFGCIDYSSIRHDGQLSDVIVGHCVAGFSPFATLVVVLLLAAFGWQAVQFVLGLSRLRAMHRFYEQLLGIPDADVQSIPWHEVVNRLSALRDQHPTTSLSSADEMELGQRTSSSLRRSHPQPLDAHDVANRIMRQENYLIALFNENILDLSVPGLRSRSPSLTRSLEWNLHFCLLGFLFDSNGQVRHAFLSERYRADLIEGLRRRFLFMAVVNAIFAPFIVLYLLLYSFFRYFEEYHKDPSNLGSRQYTQYARWKFREFNELPHLFRRRCRTSYVAASKYMDQFPKEKTAIVARFVAFVAGSFTAVLLLASVMDPDVFVHFNITPQRNVLFYIGVFGAILAVARGMIPDEHVVFEPEAMLREVIEQTHYLPQDWKGRFHSAQVHQAFGQLYTLKIYIFLQELLSVVTTPFVLWLSLPACAPDLIDFLRKYTVHVDGLGHVCSFAVFDFARQPTASTMGGAAAKGIHRQQQQQQQQQQQSGGSGRTRAPRNGMSQAKMEQSILGFRANHPDWDPAAHASTASIQRVDDDAGATTLQYGHGDGRSTSDAPTGVGAGAKVKDLIDHIYRGSGGAAGASRW
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1964_BDEBA
Sequence: MGKSWKTAGKVEKAQQKGQIFTKLAREIAVAAKAGGPDPNANARLRMAIDAAKKVSCPNDTIERAIKKGAGLLDDGKVIEELTYEGYGPHGVGVIVECQTDNKHRTAPDMRHAFKSHDGNMGESGSVAWMFERVGLIEGTKEGSFDPDEEAIEAGANEVFADEGTYEFFTAADDLDAVREALTSRGWKVTKGELSYKAKNITELSDEQRKDVEEFLNYLDDMDDTHRVHATI
What are the official names of this protein?
Probable transcriptional regulatory protein Bd1964.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2H1_BOTMT
Sequence: SLVELGKMILQETGKNPVTSYGAYGCNCGVLGHGKPKDATDRCCYVHKCCY
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (PubMed:24724078).  Shows high myotoxic activity, neutrophile activation (demonstrated by activation induction of IL-1beta production), slight cytotoxicity against Jurkat (leukemia T) and SK-BR-3 (breast adenocarcinoma) tumor cell lines, and slight antiparasitic activity against promastigote forms of Leishmania amazonensis (PubMed:24724078).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog BmatTX-I, svPLA2 homolog, Lys49 PLA2-like.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PG036_VARV
Sequence: MSSSTMDNNEPKVLEMVYDSPILPEGSSMDPNIINCINRHINMCLQHTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDHYGGYVNAILYQIRKRPNQHHTIDLFKKIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPVYSYVLYENVLYDELKCFIDYVETKYFQN
What is the function of this protein?
Plays a role in the inhibition of host innate immune response.  Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
What are the official names of this protein?
Protein OPG036, Protein N2.
What is the protein family that this protein belongs to?
Belongs to the poxviridae OPG036 family.
Protein: SYKM_SCHPO
Sequence: MISRGLLSKGILSIIKRKNTGNLIPHVYYSEYHADIEERRKALGRLGISLYPSVTSDASTTTIPVIIEKWRNKITKSEIAMVRYTVCGRISSIRYSGSKLAFFDVLYGNKKLQVVFNKKNIGTEEEMKGKFIPRLKALQKGDCIQCSGNVGRSGSGELSIYATELPKLLSPCLHPIPVKLTNYEKRFEKRFVDMMSNTKSLELLEKRYRIIESIRKFFSERGFLEVETPILSHHFGGATARPFITSDIHKLPLTLRCAPELWLKQLVIGGMNRVFELGKNFRNEGIDATHNPEFTSCEAYCAYLNLEGMKKLTEELIRFICLTINGNLQISGQTVDLEKGFEVIEFIPALQKELNVELSPLDNSENCRKQLISIFKRCEIMLPKTCTVAHLLDKLFDSLVLKYNTSSPKFVINHPEVMSPLAKSDIKLYGAVEQRISKRFELYIGGYEICNAYEEENDPVAQYHKFQAQKYDRLQLGDDETPAPDSDFVHALEYGLPPTAGWGMGVDRLVMLMTGQSKISEILPFGSLRYV
What are the official names of this protein?
Lysine--tRNA ligase, mitochondrial, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_CTESO
Sequence: MTNMRKSHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYSFMNTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FTSK_BORBU
Sequence: MKDFYQYFQFLFFFMLSVISFSLFVALTPLSNVFVFFVFNLLGQILLNVFSFLSFYLIVYPIVNWYAYKKHIFTKRFIFNWNYTVILFFTLIFLIKINSNVEKSYFIKIFLINFGIVLGNFFIFTLLILEFVVWIYLNYVFFKDVNFILDTFKFLEFKIKILFENILSYFPFSNSLDVKKDIKVYGDSVDDLKDSQVFDEKKNIINDEEYQALWSFSAFLRNNKKPSNINLDKTIFEGSDLKEASSLNKDILNENALNLDENVDEIDESCEYKYLDNLEDNKLVISGKVKACEIRTKGIISQVAISHVYNENVALNKKNDSYVIDISVFDQKEIKNDVEDIEYDKEIQKQSMILQETLKEFNINAKLIDIIKGPVVTMYAVRPDKGIKLSKITSISDNIALRLAAIRVRIIAPIPGREAVGIEIPNKRREFILISEIIDSKEFRGDFRIPFALGKEISGENIVFDLVNSPHLLIAGATGAGKSVCVNSLIASIIFSKSPDEVKLIMIDPKIVELKLFNDIPHLLTPVITDVKRALEALRWCLDEMERRYVLLDNLLVRDISSYNKKIKDENLNLMILPYLVIIIDEFADLILSARKDLENLISRLAAMARAVGIHLVLATQRPSVDVITGVIKANFPSRISFMVASSMDSRIILGSSGAEKLLGKGDMLYISSLNPFPXRIQGGFLKEREVYRLVEEVKKFGSPNYIDDEIFIDSVKEPDLVALGPSDEPMFDEALEIVKTTRKASASYLQRRLKIGYNRAARIIEIMEDMGYVGPVNGSKPREVLI
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: RTCA_SALPC
Sequence: MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTPGPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFYPAGGGAAATVVEPATSLRGLTLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMIQSEQLTELFVAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFLPVTFNLEEARGMVQVMVSKKDSGS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_MAGSA
Sequence: MSIRLLPPTLVNQIAAGEVVERPASAVKELVENAIDAGASRIDVVLAEGGQSLIAVSDDGCGMSPDEMMLAVERHATSKLPDDDLVRIRFLGFRGEALPSIGSVARLTLTSRPRGADSAWSLSVEGGAKGRPVPAAHPQGTRIEVRDLFYATPARLKFLKAARTELTHAADVIERLGMAHPDIAFSLSDGGRKVLDLAAKRGEPGAALLSRIAQVVGREFEPNALALDAERDGVRLTGWAGLPTYNRATSAAQYLFVNGRPVKDRLVIGAVRGAYQDVLARDRHPVVALFLELDPDQVDVNVHPAKAEVRFRDSGLVRGLIVGAIRHALAGAGHRASSTLTGVALGALGGGGGNSPPPSFAHYPPPRPSLPLIRAGIGAQAPLGLAEQGLGLHLPPAAPVAPPEAREGPGEASVDYPLGAAKAQLHDTYIVAETADGLVIVDQHAAHERLVFERLKLGLTEGQVARQGLLLPEVVDLGDAGAARVTERAGDLARLGLVIDSFGPGAVVVREVPALLGDDDVQGLVRDLADELAEWGASTVLEERLLHICATMACHGSVRAGRRLSVPEMNALLRRMEATPLSGQCNHGRPTHVSLSLNDIEKLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: Y1097_EXIS2
Sequence: MLSQEQLDRINELANKSKVEPLTDAETAEQKELRTAYLEAFRGSFKNQMMGIKIVDEEGTDVTPEKLKQAQEEERNKQ
What are the official names of this protein?
UPF0291 protein Exig_1097.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA2_CITBB
Sequence: MLGAYLPILVLVVIAVLFGLGSVIFSSLIGQKKPSTVKLAPYECGCEPVGSARERFSIKFYLIAMLFILFDIEAVFLYPWAVLFKRLGMFGLIEMGVFIVILFVGYVYVWKKGALEWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 2, NADH dehydrogenase I subunit A 2, NDH-1 subunit A 2, NUO1 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AZOR_RALSO
Sequence: MQVLHLDSSILGDASASRILTAAIVDELRRDNPGATVIHRDLAVEAIPHLDGAIAAGFRATGADGFDAVTLAEHARSEALVGELLASDVIVVGAPMYNFSVPSQLKAWIDRVAQAGRTFKYTETGPVGLTGGKKVIVASTRGGMYSAGPTAAMDFQEAYLKTVFGFLGITDVQFVRAERLAMGPDARAQALEAAHAAMHDVVNQAIAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: IF1_SALCH
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_PSEAE
Sequence: MSLEIVILAAGQGTRMRSALPKVLHPIAGKPMLGHVIDCARQLQPERIHVVIGHGADLVRERMAADDLNFVLQAEQLGTGHAVAQALPFLSADQVLILYGDVPLIQLDTLQRLLAQVTPDQLSLLTVDMLDPTGYGRIVRDDQGAVQAIVEHKDATPAQRQIGEINTGILAVPGKRLADWLGRLSNDNAQGEYYLTDVIAMAVGDGLVVASAQPLDAMEVQGVNDRMQQAQLERHYQRLRAEELMRQGVTLLDPQRLDVRGEISVGRDVLIDVNVVLEGRVVIEDDVRIGPNCVIRDSVLRRGAVIKANSHLEGAELGEGSDAGPFARLRPGSVLGARAHVGNFVELKNARLGEGSKAGHLSYLGDAELGANCNIGAGTITCNYDGANKFRTELGDDVFIGSNNSLVAPLKIGDGATTAAGSTITHEVPAKNLAFGRARQKNLENWKRPEKIKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_MYCBT
Sequence: MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAATGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ECCD3_MYCTO
Sequence: MSGTVMQIVRVAILADSRLTEMALPAELPLREILPAVQRLVVPSAQNGDGGQADSGAAVQLSLAPVGGQPFSLDASLDTVGVVDGDLLVLQPVPAGPAAPGIVEDIADAAMIFSTSRLKPWGIAHIQRGALAAVIAVALLATGLTVTYRVATGVLAGLLAVAGIAVASALAGLLITIRSPRSGIALSIAALVPIGAALALAVPGKFGPAQVLLGAAGVAAWSLIALMIPSAERERVVAFFTAAAVVGASVALAAGAQLLWQLPLLSIGCGLIVAALLVTIQAAQLSALWARFPLPVIPAPGDPTPSAPPLRLLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAIAVRPEALSVVGWYLVAATAAAATLRARVWDSAACKAWLLAQPYLVAGVLLVFYTATGRYVAAFGAVLVLAVLMLAWVVVALNPGIASPESYSLPLRRLLGLVAAGLDVSLIPVMAYLVGLFAWVLNR
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
What are the official names of this protein?
ESX-3 secretion system protein EccD3, ESX conserved component D3, Type VII secretion system protein EccD3, T7SS protein EccD3.
What is the protein family that this protein belongs to?
Belongs to the EccD/Snm4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_PHEZH
Sequence: MPPVTPLLDTVSSPADTRGLSIAQLRQLADEVRAETIDAVSQTGGHLGAGLGVVELTVALHHVYETPKDILIWDVGHQAYPHKILTGRRDRIRTLRQGGGLSGFTKRAESDYDPFGAAHAATSISAALGFCAARDREGRDNKVVAVIGDGSMSAGMAYEAMNNAYETTKQLTVILNDNDMSIAPPVGGMSAYMARLVSGGGYQSLRNLGKAVSRAFPRPLQEAARKAEEYARGMVTGGTFFEELGFYYVGPIDGHDMDALVHVLQNARKIDDKPVLVHVVTQKGKGYAPAEKAADKYHGVVKFDVVTGAQAKSQAAAPSYTKVFAQELVKHAERDERVVAITAAMPSGTGLDLFGQRFPERTFDVGIAEQHAVTFAAGLAADGMKPFAAIYSTFLQRGYDQVVHDVAIQSLPVRFAIDRAGLVGADGPTHAGSFDVGFMGQLPGMVVMGPADEAELARAIATAVAIDDRPSAFRYPRGEGVGVEIPALADPLEIGRGRIVREGTAVAILSFGTRLGESLKAADMLAARGLSATVADARFAKPLDVDLLLRLAREHEALITVEEGAVGGFGGFVLHALAEHGALDRGLKIRTLTLPDIFQDQDKPEAMYAQAGLDAEGIVRAALAALGIDNASVKGRRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL10_PSE14
Sequence: MAIKLEDKKAIVAEVNEAAKAGLSAVVADARGVTVGAMTGLRKEAREAGVYVRVVRNTLLKRAVADTEFSVLNDVFTGPTLIAFSNEHPGAAARLFKEFAKGQDKFEIKAAAFEGKFLAANQIDVLASLPTRNEAISQLMSVIQGATSKLARTLAAVRDQKEAAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PETN_OENPA
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.