PharMolix/UniProtQA huggingface dataset:
Protein: MURB_STAAS
Sequence: MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_XYLFA
Sequence: MVINDIESLTDQALADVAAAQNLDHLEVLRVALLGKNGSITLQLKQLGKLPVEQRKAIGEKVNCVRDLISVALMDRKAALESAALSKRLIDERVDVTLPGRRGERGGLHPVTRTLERITEIFARLGYELVEGPEIEDDWHNFEALNFPLHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMSDHRPPLRMIAAGKVYRSDSDQTHSPMFHQIEGLLIDKHATFVHLKGTLSEFLRAFFERDFEVRFRPSYFPFVEPGAEVDIAWQQSDSSVRWLEVLGCGMVHPNVLKNVGIDSECYTGFAFGLGVERFAMLRYGVDDLRAFFENDVRFLRQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_NOSS1
Sequence: MSRYRGPRLRIVRRLGDLPGLTRKSARRAYPPGQHGQNRKKRSEYAIRLEEKQKLRLNYGLTEKQLLRYVRRARRVTGSTGQVLLQLLEMRLDNTVFRLGMAPTIPAARQLVNHGHVTVNGRVVNIASYQCRPGEEIAVRDKAPSRKLVENNLQYPGLANLPSHLEFDKNKLVGKVNSVIEREWVALQVNELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RHAA_LISIN
Sequence: MGQETEISKRYQVAKERYQAIGVDTEKALKTLKDIKISMHCWQGDDVKGFLNPDGELTGGIMATGNYPGAAHTPKQLRQDLEKAYSLIPGKHKLNLHAIYVDTDEKVDLNEIEPKHFTPWVEWAKEQGLGLDFNPTFFSHPMFKDNYTLASPDKEVRDFWIEHGKRSRKISEYFGKELGQTSINNFWVPDGIKDCPIDRYTPRKRLMEALDEVFAEKLDEKYTQEAVESKLFGLGAEAYTVGSHEFYMGYGITRDKLICLDAGHFHPTEVISNKLSSLALFSKGVMLHVSRPVRWDSDHVVIMDDELIEIGRELVRNDLLGITNIGLDFFDATINRIAAWVVGTRNTQKSLLKALLEPTADLKKMELENDFTSRMAITEELKDFPFGDVWNYFCEINGVPVGLDWLKEVKAYEKDVLLKR
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BLOPB
Sequence: MTTMLSIVQVKNNEIPKTLSIKKFKLIAGVDESGCGSLVGSVIAAAVILHSIQPISGLADSKTLNKNKRLNLYKNIIKNALAWSIGYADVTEIDRSNILEARLLAMKRAVHNLSVKPDLILIDGNRSPGFTEIPYQCFNKGDARIAIISAASIIAKVTRDQDMIILDKQYPKYGFAQNKGYPTFFHLKQLALYGPISQHRKSFAPVKHVISDINRKL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SHEON
Sequence: MSNRVIIFDTTLRDGEQALAASLSVKEKLQIAMALERLGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALSRALEKDIDAAAQALSVAEQFRIHTFISTSTIHVESKLKRSFEQVLEMAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEAAIHAGARTINIPDTVGYTVPSEFGSIIQTLFNRVPNIDQAIISVHCHDDLGLSVANSITAVQHGARQIECTMNGIGERAGNCSLEEIAMILATRKNLLGFETGINAKEIHRTSNLVSQLCNMPIQSNKAIVGANAFTHSSGIHQDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMEEMGYSSQDYNLDALYEQFLHLADKKGQVFDYDLEALAFIEAQAAEDNFYQLRQLVVQSDSTEGVATATVRIEVGGEIKTEAATGNGPVDAAYNAIARATDRRIDIISYKLGAKGVGQDALGQVDITAVYHEQNFHGVGLATDVVEASARALVHVMNLTCRADKVADYKQNMHKNRELGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RET3_CAVPO
Sequence: THLFQPSLVLDMAKVLLDN
What is the function of this protein?
IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina.
What are the official names of this protein?
Retinol-binding protein 3, Interphotoreceptor retinoid-binding protein, IRBP, Interstitial retinol-binding protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Note=Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells.
Protein: BRIX_SACS2
Sequence: MHIHRTRIVITSSRDPSIRTRNFLNVLTFVLPDSVKITRGKKSKIEIFERAINLGALYLLFVLAKNGNPLRIIVYDLESLSIKYFFKLSGLSLPSDYNVSLNQIKGHSNVCIKLNECDFLRDFLVDMNMYNLTNNCDVVVNSRLIHTNICELLFMLTTKNIKFLKMILEA
What is the function of this protein?
Probably involved in the biogenesis of the ribosome.
What are the official names of this protein?
Probable Brix domain-containing ribosomal biogenesis protein.
Protein: METK_BLOFL
Sequence: MTRFLFTSESVSAGHPDKIADQISDSILDSILEQDPKARVACETYIKTGIVLIGGEITTTASVNIEKIARNTIQEIGYTHPKMGLDANSCVILSVINQQSPEIQYSINHDSDRTQQGAGDQGSMFGYATNETDVLMPAPITYAHRLIQRKSKLRKNGTLPWLGLDAKSQITFAYDENNKIIHITAVVLSVQHNKNIPLEALREATMEEIIKPVLPQKWLSKQTKFFINSGGTFTIGSPISDCGLTGRKIIVDTYGGMARHGGGSFSGKDPSKVDRSAAYAARYAAKNIVAAGLAERCEIQLAYAIGIANPIAVNIETFGTEKVLHSTLVTLINNFFDFSPHGVIKMLNLARPIYKDTAVYGHFGREQFPWEKIDKVDLLRNSAKI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAP2_MOUSE
Sequence: MALSYLRPWVSLLLADMALLGLLQGSLGNLLPQGLPGLWIEGTLRLGVLWGLLKVGELLGLVGTLLPLLCLATPLFFSLRALVGGTASTSVVRVASASWGWLLAGYGAVALSWAVWAVLSPAGVQEKEPGQENRTLMKRLLKLSRPDLPFLIAAFFFLVVAVWGETLIPRYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSFSAGCRGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAGQVVREAVGGLQTVRSFGAEEQEVSHYKEALERCRQLWWRRDLEKDVYLVIRRVMALGMQVLILNCGVQQILAGEVTRGGLLSFLLYQEEVGQYVRNLVYMYGDMLSNVGAAEKVFSYLDRKPNLPQPGILAPPWLEGRVEFQDVSFSYPRRPEKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGEPLTEYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEMTNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWRSQGDRTMLVIAHRLHTVQNADQVLVLKQGRLVEHDQLRDGQDVYAHLVQQRLEA
What is the function of this protein?
ABC transporter associated with antigen processing.  In complex with TAP1 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules.  Uses the chemical energy of ATP to export peptides against the concentration gradient.  During the transport cycle alternates between 'inward-facing' state with peptide binding site facing the cytosol to 'outward-facing' state with peptide binding site facing the ER lumen.  Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to hydrolysis-competent 'outward-facing' conformation ready for peptide loading onto nascent MHCI molecules.  Subsequently ATP hydrolysis resets the transporter to the 'inward facing' state for a new cycle.  As a component of the peptide loading complex (PLC), acts as a molecular scaffold essential for peptide-MHCI assembly and antigen presentation.
What are the official names of this protein?
Antigen peptide transporter 2, APT2, ATP-binding cassette sub-family B member 3, Histocompatibility antigen modifier 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=The transmembrane segments seem to form a pore in the membrane.
Protein: RBFA_BUCAT
Sequence: MEKLFNRSDRIAQELQKKIAAIIQHSLKDPRIKTIITVSEVQVSKDLSYAQIFVSFLESDNNEKVKKKITLLNRASSYIRKLLCKRMKLRIVPNIIFHHDDSFLKGNKISCILENLTKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_LACAC
Sequence: MGKFVVLDHPLIQHKLTIIRRKDTGSNEFRRIVGEIGGLMTYEITRDLPLEDVEIETPMGKTVQKEIAGKKLTIVPILRAGMGMLNGVLEMVPSAKIAVIGMYRDEETLKPHEYFFKAPKDIAERECLVVDPMLATGGSANDAIAALKKRGVKDIKLAVLVAAPEGIKAVQEENPDVDIYAASEDDKLLDNGYIFPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NAPA_CAMFF
Sequence: MDRREFIKSSAAAAACSAAGIAVPSSLSAAENQDGWRWDKSACRFCGTGCGIMVATKNGKIVAVKGDPLAPVNRGLNCIKGYFNAKIMYGEDRITKPLLRVNANGEFDKKGKFQEVSWKRAFDEMEKQFRKTYAELGPTGIGVFGSGQYTIQEGYAISKLIKGGFRSHNIDPNARHCMASAVVGFMQTFGIDEPAGCYDDIELTDTIVTWGANMAEMHPILWSRVSDRKLQNSDKVKVVNLSTYSTRTSNIADIEIIFTPHTDLAIWNYIAREIVYNHPEAIDEEFVKANCVFTTGPVDIGYGMRANIKHPKYLPSELDTAAKEKSTVLSENEGVTLAYLGMKAGDTLENKSTGAPDKHWIIQYEDFKKALAPYTLDFVAKLAKGDPNEDLEEFKKKLKALADLYIEKNRKVVSFWTMGMNQHTRGVWVNEQSYMVHFLLGKQAKPGSGAFSLTGQPSACGTAREVGTFSHRLPADMVVANPKHREITEKIWKIPAGTINPKPGAPYMKIMRDLEDGKVKFVWVHVNNPWQNSANANHWIKAAREMDNFIVVSDPYPGISAKVGDLILPTAMIYEKWGAYGNAERRTQHWRQQVLPVGDAMSDTWQYMEFAKRFKLKDFWGEVKVDGKLTLPNVLDKAVAMGYNPENTLFEVLFANKSAMKFSSDDKIMAGYDNTEVFGDSRNVVGSDGNVFKGYGFFVQKYLWEEYREFGLGHGHDLADFDTYHKVRGLRWPVVDGKETLWRFNTKYDVYAKKDNPNGDFSFYGNKNGALVTGDLAKATSKEKEALKSRAKIFFRPYMDPPEMPSKDYPLWLCTGRVLEHWHSGTMTMRVPELYRAVPEALCFMNEIDGNKFGIKQNDIIWVESRRGKVKARVDFRGRNKPAEGLIYVPWFDENVFINKVCLDATDPLSKQTDFKKCAVKIYKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: DAPB_COXBU
Sequence: MAINVIINGINGKMGRVVKENITAQSDLELVSGTGRQDDLAKTIQTTHADVVIDFTTPQSVFHNAEIIIQSGARPVIGTTGLTLEQIALLDKQCRNKKLGAIVAPNFSVGAVLMMKYAKEAAHYFPDVEIIEMHHSQKIDAPSGTAIKTAQMIGEMRSSKKDEPFKDRARGEIKNGIPIHSIRLPGLFSHQSVIFGSNGETLTIRHDGMDRNCTMPGIFMACRKVMELDYLVYGLENLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA6_CHICK
Sequence: MAPKGKVYRGSVKDFPGFNASQDADALCNAMKGFGSDKDAILDLITSRSNKQRLEICQAYKSQYGKDLIADLKYELTGKFERLIVSLMRPPAYSDAKEIKDAIAGIGTDEKCLIEILASRTNQEIHDLVAAYKDAYERDLEADVVGDTSGHFKKMLVVLLQGAREEDDVVSEDLVEQDAKDLLEAGELKWGTDEAQFIYILGRRSKQHLRMVFDEYLKISGKPIERSIRAELSGDFEKLKLAVVKCVRSTAEYFAERLYKAMKGLGTRDNTLIHIMVSRSEIDMLDIREVFRTKYDKSLHNMIKEDTSGEYKKALLKLCEGDDDAAAEFFPEAAQVAYRMWELSAVAKVELRGTVQPASNFNDDGDAQVLRKAMKGLGTDEGAIIEVLTQRSNAQRQQILKAYKAHYGRDLLADLKSELSGSLANLILGLMLTPAQYDAKQLRKAVEGDGTDESTLVEIMATRNNQEIAAINEAYQQAYHKSLEDDLSSDTSVHFKRLLVSLALGNRDEGPENLTQAHEDAKVVAETLKLADVPSNDSSDSLETRFLSILCTRSYPHLRRVFQEFVKMTNHDVEHAIRKRMSGDVRDAFVAIVRSVKNKPAFFADKLYKSMKGAGTDERTLTRIMISRSEIDLLNIRGEFIDLFDKSLYQMIEKDSGDYCKALLALCGGDD
What is the function of this protein?
May associate with CD21.  May regulate the release of Ca(2+) from intracellular stores (By similarity).
What are the official names of this protein?
Annexin A6, 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Chromobindin-20, Lipocortin VI, P68, P70, Protein III.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: CALS4_ARATH
Sequence: MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD
What is the function of this protein?
Involved in callose synthesis at the forming cell plate during cytokinesis.  During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals (By similarity).
What are the official names of this protein?
Callose synthase 4, 1,3-beta-glucan synthase, Protein GLUCAN SYNTHASE-LIKE 9.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 48 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDTK_SALTY
Sequence: MQKYTSEARQLLALRIPVILAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLVMIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSMRDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTVTLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOZ_YERE8
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQIQSGGKDALVPEENDKVTVIALREIEEGLITNQILDVRERQEQQEQEAAEIQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: VPS36_XENLA
Sequence: MDRFSWCTGLLDIDETLVIQQRGVRLSDGEEKTKFDSGTLLLTTHRLIWRDQKNHDFCIAFPLSQIVFTEEQAGGIGKSAKIVVHLHPATPNKEPGPYQTSRYSYVKLSFREHGQIEFQRRLAEELTQRRWERLSASASPSMQMNKGPQTGRIKAVGIVGIERKLEEKRKETDKNISEAFEDLSKLMEKAKEMVELSKSIATKIKDKQGDISEDETIRFKSYLLSMGIANPVTRETHGSGTHYHMQLAKQLATMLQAPLEERGGIMSLTEVYCLVNRARGMELLSPEDLVNACKMLESLKLPIRLRVFDSGVMVIEHQSHNEEEMVASALETVSEKGSLTSEEFAKIVGMSVLLAKERLLLAENMGHLCRDDSVEGLRFYPNLFLTQS
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 36, ESCRT-II complex subunit VPS36.
What is the protein family that this protein belongs to?
Belongs to the VPS36 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: ARND_SALG2
Sequence: MTKVGLRIDVDTLRGTREGVPRLLATLHRQGVQASFFFSVGPDNMGRHLWRLIRPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHETGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVRAKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWIISRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPTSPESLPLGQIVRGHIPGREGWLGCQQAASAS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: ACTH_MOUSE
Sequence: MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YDBL_BACSU
Sequence: MRNFITALPIVLLLGFSFVSFMFQFEHLVYFRLALGLFSLVGLYMIYKMKTGIRYFIIYLYASWIVLAAVTAFEEPIFSSFFFGGLVMTMGYLTYMLIYLGMKQDRDANPV
What are the official names of this protein?
Uncharacterized protein YdbL.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_ECODH
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y1631_HAEIN
Sequence: MEFSLQYITIFIFVILFLIGLFSSKSRSTRRNEKKSRLYLSTENKINIVNKNDHLDVVILSKYKRKALMNKSEYQLFLRLEKLLSKGYQEFRLFTQVSMGEFLESIDKEAHFAINSKRVDFLIVDKNGYAVIVIEYQGQGHYQDNAAKRDAVKREACRKAGVIFLEFQPNYGKAELEFVGENLKRYLIKN
What are the official names of this protein?
Uncharacterized protein HI_1631.
Protein: ATPA_RALPJ
Sequence: MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGEYEHISEGDEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAYAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEHIEKITNGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGVRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDTLKTKYADLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL16_ACIB5
Sequence: MLQPKRTKFRKVHKGRNTGLAHRGSTVSFGSIAIKATERGRMTARQIEAARRTISRRIKRGGKIFIRVFPDKPITEKPLEVRMGNGKGNVEYWVCEIKPGKILYEIEGVNEDLAREAFALAAAKLPFKTTIVTRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PTPB_STAAB
Sequence: MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: RS3_PSEF5
Sequence: MGQKVHPIGIRLGIVKEHTSVWYADGRTYADYLLADLNVREYLQDKLKSASVSRIDIHRPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIEEIRKPELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFKGEVIGGRQEELKPQAPAPRKKAAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.