PharMolix/UniProtQA huggingface dataset:
Protein: RRC1_CAEEL
Sequence: MEGIEESFAPLSPKSPFARRNGRSLRIQRLVDCQHFHYSSVELGPVRVAIIAINADENATERIKMRVESESNSWLVERSREDWAVFDRQLHRCVFERRHSRLDELFPLIHLETAKFEEVLVKYTERLSELTGSIITCYPVLKFLEIDSRGGHFEPAEETSINVPAIAAAVVTKDFEPTESSQLRLRVGDIVSITEMSTASPSEQTFWKAKLTISNQKIVDPQNARLGFEIGYFPRDCVMLIDDKRLPNPLNNEQKASTRNARRYMTTMFRNRRREPIFGLELTDLYMRTGKKVPVIVEKCCASIEDQGIVTGIYRQCGIQSNIQRLRAKFDSGAEPDLHEFGQRDIYSVSSLLKQYFRQLPNPLFTYQAYPKLIEAFEKEDSLSEKVESLRFSLETMPEAHYRTAKFLMEHLTRLCKSKSLTDMTSKNLAIVWSPNLFRPPPTLNGADTHLLSGLNVHTAICDFFIENSESLFVNDIDEEQSKCTSVENSFTTISKSATMSDMRSESESKWPRFFRGKSVEGFWKFNRKQQTSTGELCGSPTSEVKWRSRSTRSHSTDAAFQSSRTDSFIQLMHTGMDQIREGMRIFRARARSMRPTSRPPPSPRTRRARFSNGSSNNVQKLNESDIQHEIPLATTEPSITPEPKNTVDPHQIMTRTISVNDSDDQSFEENGLREMRERKVMFKAATQEHVATFHERSSPVEEWSSDSRESLHLEMSRYDNVSPSGTITRNQREPITNLSPAAQMLFFESSRASHLFSA
What is the function of this protein?
Functions as a GTPase-activating protein (GAP) for ced-10/rac-1 and CDC42.
What are the official names of this protein?
GTPase-activating protein rrc-1, RhoGAP for Rac-1 and Cdc-42.
Protein: FGF1_NOTVI
Sequence: QKPKLLYCSNGGYFLRIFPDGKVDGTRDRSDPYIQLQFYAESVGEVYIKSLETGQYLAMDSDGQLYASQSPSEECLFLERLEENNYNTYKSKVHADKDWFVGIKKNGKTKPGSRTHFGQKAILFLPLPVSSD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrins.  Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery (By similarity).
Protein: Y1704_MOOTA
Sequence: MSGHSKWANIKNRKAKVDEKRGRLFTKIGREIIIAARMGGGDPEGNMRLKAAIAKAKAANMPNENIQRAIMRGTGELEGAAYEEMTYEGYGPGGVAMLLNIATDNRNRTASEIRYIFSRGGGNLGESGCVAWMFNPKGVITVEVPAGDKREEVILQAIEAGAEDVDDEDDEVLEIKTAPGDLEAVREALEASGVTITHAEVEMVPQTTVTIDDPETAGKVMRLIERLEDHDDVQAVYTNADIPAAIMDQLDI
What are the official names of this protein?
Probable transcriptional regulatory protein Moth_1704.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOR8_ARATH
Sequence: MTKVHPKFPSTCEESLCDSKAAVVLTVWKKSLLFNCDGFTVYNANGELVFRVDNYMNCPRDNIVLMDASGFPLLSIRRKKLSLGDCWMVYDGETERDPIFTARKNVSIISNRKSLAWVSAKKTVLYEIEGSYGQRSCKILDERRNKKKTAEIKRKETVIGGVAFGKDVYKLIVESEMEPRVAMALTIILDQMFRSS
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 8.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: Y501_MYCPN
Sequence: MKEKIPFYNEKEFHDMVKKTKKGTFSGWYIIDKDNNSVEFSGKFNRQFKLNKPVIPVNTEYVTRKEFNEYKNSNDQRLTKIETTLAAQGEQINKLTQTVEKQGEQINQLVQVVLLHGEQINKLTQTVEKQGEQIKELQIEQKAQGETLKLILQTLQKMSDRLDKMEVKMDKMEVKMDKMEVKMDKMEKRIDKLESK
What are the official names of this protein?
UPF0134 protein MPN_501.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: AROA_BRAHW
Sequence: MTLTIKPSEIFGSIYIQMSKSDAHRALIASSLAKTPSIIKRWIDNVSVDVEVTKNAVSNFADLEIIDDNLKVFPKKEYKKELVIDVKESGSSLRFLIPIMSAFGITCTFTGSKKLFSRPIDVYKKIWKEEGLEFIHSEDSIKISGQLKASNFKVLGNLSSQFLSGLLFALPLLDGNSNIIIDGELESEPYVMMTLKTLKAANIETLRHDNNIIEVYGNQEYSGIDYEVESDWSHAAFFAAAGALGGETTLYGLNKYSIQGDKEILNILKFMGASVSYNDDNSITIKKTNRLNALDIDMSDIPDLGPIITTLAATAKGRTRLYNAGRLRYKESDRMNDLMDSFSRIGANIEVSEDEILIEGVERLKGGNTTSHNDHRIAMALAVASAVSDNDIIIDDAESINKSSFNFIEQFRSIGAKVVS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRD_METMP
Sequence: MDATSFILPLAEITIAGAIINASVHFVPVGGAPAAMATSTGVGTGTTQLAAGAGFTGLLAAAAMASQAGVSLSNPVHMLLIMLSGAVGAMIMLGLTMLIGQIIYVYGIGIVPAADKCEKDPITGDIQKPYITPGTTGHGIPTVCFVSGTIGAALGGLGGALAYIALQQLGFAAAIAGVLAVGFFFMNAVLASYNIGGTIEGFHDPKFKKMPNGVIASFVSSLIAGAVLIGMAMGL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit D, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D.
What is the protein family that this protein belongs to?
Belongs to the MtrD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_BORA1
Sequence: MVQTLQKKGRVVVGMSGGVDSSVTAWLLKQQGYEVVGLFMKNWEDDDDSEYCSTRQDLLDAASVADLIGVEFEYVNFASEYKDRVFADFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAEHIATGHYARVRAVDTARGQRFQLLKALDASKDQSYFLHRLNQAQLSRTLFPLGELHKTEVRRIAHEIGLHNAAKKDSTGICFIGERPFREFLNRYLPTAPGPILTPEGRRLGQHHGLAFYTLGQRKGLGIGGVKGQQREDGTADAWYSARKDLKNNALYVVQGHDHPWLLSDTLRAQDVNWVDGEAPAAGAYAAKTRYRQADAPCELRADEAGFDLSFAQAQWAVTPGQSAVLYDGDVCLGGGIII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JUN_BOVIN
Sequence: MTAKMETTFYDDALNASFLQSESGAYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVSGAGLVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGSLSSGGGAPSYGAAGLAFPAQPQQQQQQPPQPPHHLPQQIPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
What is the function of this protein?
Transcription factor that recognizes and binds to the AP-1 consensus motif 5'-TGA[GC]TCA-3'.  Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to the AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing its transcriptional activity (By similarity).  Together with FOSB, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway (By similarity).  Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.  Involved in activated KRAS-mediated transcriptional activation of USP28.  Binds to the USP28 promoter.
What are the official names of this protein?
Transcription factor Jun, Activator protein 1, AP1, Proto-oncogene c-Jun, Transcription factor AP-1 subunit Jun, V-jun avian sarcoma virus 17 oncogene homolog.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3001_SYNP2
Sequence: MIVSDNFTSSSNTGADLASSVSENRSHFIAESHYREWVEGSGVAPEIARLNVRSLSGMTPYEYLLYSDEPALRRNDGRLRDTWLKRYAFVEHGGWWCSGIDIKTGKDSLWGCFKGDRPRKDREDKKPIKYEHPPRVATEIFTLKVDRGTWRKIAKRHKVELPETDQGFWEWVLAHPELPIIITEGAKKAGALLTAGYCAIGLPGIYNGYRTPKNDHGEPMRQLRHLIPELDLLAKNNRAIAFCFDQDKKPKTIKAVNGAIQTTGALLEKAGAKVSVITWHQDAKGVDDLIVEHGAKALHNRYKHRKPLAVWEMDNLTDITTQVDLTVDQRYLDIDPRAIPKDAQIIFIKSAKGTGKTEWLGKIVKLAQDDCARVLVLTHRIQLAKELARRLDIDHISELDSSPTGGALGMAMCIDSLHPDSQAHFNFMEWHGAHIVLDEIEQVLGHALGSSTCTQDRAKILETFYNLILYALRTGGKLYCSDADLSPISYELIKYILDGCEFKPFTILNTYKPCLEQQRDLFFYEGNDPRDLLTNLRQAIENGEKTLVFTAAQKTASTYSTQNLESLFREKYPDKRILRIDAESVAEPGHPAYGCIDSLNAILPLYDIVLCSPAVETGVSIDIKDHFDSVWGMGSGVQTVNGFCQGLERLRDNVPRHVWIPKFSPHSNRIANGGYTAKAIARDQHRYAELTHKLIGEHAAECSGLEDSLKPFLWAYCRYAALANRGFGSYREAILNKLLSEGYVQKDLSEIDPALAKDYRDELKAVKDHNYLQERVAISKVENPDDRQYEKLKRQRAKSETERHQERHGKLSRSYGLTVTPELVEKDDDGWYSQLQLEYYLTVGKAFCSARDRAKYDQLQHEGFVFKPDINRRSLSPKIHLLELLNIHQFLKPGVTFTGASLEGFKENCLRYAKPIKWILGRTITDKMSPLEIAQALLGKLDRKLEYKGRFGSRDNRQRVYEAIAPNDQREKVFAHWLQRDQAKLGAVSNPCINRFIQEA
What are the official names of this protein?
Uncharacterized protein SYNPCC7002_B0001, ORF 1, ORF943.
Protein: SYY_STRE4
Sequence: MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIKEQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIETGISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAELKQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYSLSTADRIDNQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM10_TALSN
Sequence: MLEFMDYVQLAFAEATRWNQDNSYSSLTAIAESLLDFHVPERLQVHLSSLSTPHFATSYTLGTVGLIDGSVSYLFSTVPLNNTPSQSGVIPLRRLVRGYRQIEAPVPPIRNWGWDAIPSHDSSQIIDSADINQDDIVRKATLLHATLHLPPPSTLNALFQRRISPTTQITAALVSTQGPPLIKSAPSAALLAQISHDTGTFSNEYLFSTDNALFGWRGLWNIGLDPSPGKQSTDKVSLLSAGAEAYYSPISSLVGLSTGLKFTTLPAAGRALSSSSSSSPGSNPSPISSFPYTLTLTLTPLTGSLSTTYSARASPNLAFSSRFGFNVYSWESEMVAGCEIWRKSPRTQPAEADDGLDWARRKMGIVKERAAEKISALSSSSSTPQAVEESEGDSVVKIRVDQSWNVRLLWEGRVKSLLVTAGVSLGPGTFTALSSGPASPTSSSAPVAMAGAPPTSRPSYWQGVGVSILYSS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the receptor tom22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the mdm12-mmm1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the tom40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component mdm10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: LALBA_PIG
Sequence: MMSFVSLLVVGILFPAIQAKQFTKCELSQVLKDMDGYGDITLPEWICTIFHISGYDTKTIVHDNGSTEYGLFQINNKLWCRDNQIQSKNICGISCDKFLDDDLTDDMMCAKKILDNEGIDYWLAHKALCSEKLDQWLCEKM
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: O162_CONST
Sequence: MKLTCVVIVAVLLLTACQLITADDSRGTQKHRSLRSTTKVSKAADCIEAGNYCGPTVMKLCCGFCSPYSKICMNYPKN
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like 2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_PSEA6
Sequence: MKESVQRKLESLTERFEEVQALVSQPEIIADQDKYRALTKEYSQLEGVVKCFADYQGAQGDFESAQEMMQESDPEMREMAQEEYKSSKQAIEQYEDELQILLLPKDPNDESNCFIEIRAGAGGDEAAIFAGDLFRMYSRYAEARRWKVEVVTMNEGDHGGYKEVIANIIGDGAYGVLKFESGGHRVQRVPETESQGRIHTSACTVVVMPEVPESEAIEVNKADLKIDTFRASGAGGQHVNKTDSAIRITHVPSGIVVECQDERSQHKNRAKAMAVLQSRLNKLEEEKRQAEETSTRRNLVASGDRSERIRTYNFPQGRVTDHRINLTLYRLDDVVAGDLDAVLEPIRQEHQADLLASLSDEG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_BURPS
Sequence: MSFSRSEAAPAAPLPDLAATLAAPRDDAFQQLGAAFVTRLPAAPLPAPYVVGFSDDAARMLGLEPALRDAPGFAELFCGNPTRDWPQASLPYASVYSGHQFGVWAGQLGDGRALTIGELAHDGRRYELQLKGAGRTPYSRMGDGRAVLRSSIREFLCSEAMHHLGIPTTRALAVIGSDQPVVREEIETSAVVTRVAQSFVRFGHFEHFFANDRPEQLRALADHVIERFYPACRDADDPYLALLAEATRRTAELVAQWQAVGFCHGVMNTDNMSILGLTIDYGPFGFIDAFDAKHVCNHSDTQGRYAYRMQPRIAHWNCFCLAQALLPLIGLHRDAPSEDARAERAVEDAHAVLGRFPEQFGPALERAMRAKLGLALEREGDAALANQLLEIMDASHADFTLTFRHLARVSKHDARGDAPVRDLFIDRDAFDRWANLYRARLSEEARDDASRAAAMNRVNPKYVLRNHLAETAIRRAKEKDFSEVERLAAVLRRPFDEQPEHDAYAALPPDWASTLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: TDCC_SHIBS
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEF_HV1A2
Sequence: MGGKWSKRSMGGWSAIRERMRRAEPRAEPAADGVGAVSRDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVRPQVPLRPMTYKAALDISHFLKEKGGLEGLIWSQRRQEILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCFKLVPVEPEKVEEANEGENNSLLHPMSLHGMEDAEKEVLVWRFDSKLAFHHMARELHPEYYKDC
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: MURD_METFK
Sequence: MLQLKDKQVLVLGLGDTGLSALRWLARQGARLSVADSRALPPGLDAVRQEFPGMAIHLGPFTAAAFKEAELIVASPGVPVAEPQVQAAIERGVPVVGDVELFAQARSAHAKVIAITGANGKSTVTTLVGEICKAAGFKTVVAGNIGLPVLDVINDAVDVYVLELSSFQLETTYSLAADAATVLNISADHMDRYADMQAYANAKARIFTRAGLQVLNADDAWSRGMAAEGVAQLTFGLDAPRSAQDFGLLHDAGEAWLARGQRKLMPVADLNITGLHNAANALAALALCTVLDIDEVVALQALRDFKGLPHRVQWVADIDGVSFYDDSKGTNVGATVAALHGLNRKLVLIAGGDGKGQDFAALRAPVAKHARAVVLIGRDAGVIADALQESGVLLEYGDTLEEAVVKAFNLADRGDAVLLSPACASLDMFRNYVHRAEVFVKAVTDLQKKEVSA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_XANP2
Sequence: MPRAVAGPEIERLIQLIARLPGLGPRSARRVALHLIKKREALMAPLAAAMTDALGKIVECRRCGNVDVCDPCTICTDTSRDRRTLVVVADVGDLWALERAGVLNAPYHVLGGVLSPLDGVGPEDLNLAKLVTRVHEDEVGEVILALGATVDGQTTAHYITDLLREAHVRVTRLAQGVPVGGELDYLDEGTLSAAIRARTQM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: FCAMR_PONAB
Sequence: MPLFLILCLLQGSSFALPQKRPHPRWLWEGSLPSRTHLRAMGTLTPSSPLCWQEESSFAAPNALKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNHYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTISAGPSSTLPTATPAAGELTMRSYGTASPVANRWTPGTTQTLGQGTAWDTVASTPGTSMTTASAEGRETPGATRLATPGTGSWAEGSVKAPAPIPESPASKAPAPIPESPASKSRSMSNTTEGVWEGTRSLVTNRAKASKDRREITTTKADRPREDTEGVRIALDAAKKVLGTIRPPALVSETLAWEIFPQATPVSKQQSLSSIGETTPAAGMWTLGTPAADVWILGTPTADVWTSMEAASGEGSSAGDLDAATGDRGPQVTLSQAPAVGPWRPPGKESFVKSTFPEDESSSRTLAPVSTMLALFMLMALVLLQRKLRRRRTSQEAERVTLIQMTHFLEVNPQPDQLPHVERKMLQDDSLPAGASLTAPERNPGP
What is the function of this protein?
Functions as a receptor for the Fc fragment of IgA and IgM.  Binds IgA and IgM with high affinity and mediates their endocytosis.  May function in the immune response to microbes mediated by IgA and IgM (By similarity).
What are the official names of this protein?
High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor, Fc alpha/mu receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HHEX_CHICK
Sequence: MQYQAPGAAPAAALGVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAAPAPHSLPAPPPPTLPSPNSSFTSLVAPYRTPVYEPTPIHPAFSHHLAATYGTGAYAGPLYSFPRAVGDYTHALIRQDPLGKPLLWSPFIQRPLHKRKGGQVRFSNEQTIELEKKFETQKYLSPPERKRLAKLLQLSERQVKTWFQNRRAKWRRLKQENPQATKKEEAEGTGDHGDPRSEGSPSPAGGGEAEPQDSPSAASQEDPESDVSDDSDQEVDIEGDKGFYSATR
What is the function of this protein?
Recognizes the DNA sequence 5'-ATTAA-3'.  Transcriptional repressor.  May play a role in hematopoietic differentiation.
What are the official names of this protein?
Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL104_PLAVT
Sequence: MRSAYPVLTALLVVASSQIAAGSGHQLQAYDHDRITDDNAVMKSLSTRFLRGSRDVHNNVANEERSVYSVLARMIKKGIKKMPRTAEVLKMKPHIKKASKKSPHEARLVKELFHAAEAKETMQGAREYKKLRRATRAAVEALEKHWNPSKTAVSGDAFHDIHSNQMLSVKKWKFNLTGLKPMVVNDEHHGMIDSVHKAFLTVCDKNVKPTRAETSYLWGLMNWKLAKYPRRSHKESLIEHAQRRVLLDMRKMKATKKVWPEWENLPDSLKFGVLDYLLNLHYQRLVRMYNIFARNRPDRNPAPLNPELNPVGNTGTSAAMAVAENPKGQSPYPSTPLTAASTSKGGRSNLKKRSKRTSDGNTDTASFPSKKLKVRSSKSVMPLLTEPTTSGDHSAPAKKSKSSSSGPSRAFAPDKSGDQTFITENSRLSFDGPSSAVDPFKQSKVHESKSLAPSSSVLTPEDVDTELSLGGIYDRSTYKAPSKP
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 104.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: FLIF_BRUME
Sequence: MAVVWMQQNFQQLIEQLKGTLGKLGARKLIALGLVGAALMGAILYTSIYLGRPSYETLYVGLSRDDVNRMGLALGEAGIPFDVKSDGSSILVPIGKAENARMYLAEKGLPTSNNAGYELFDNMGSLGLTSFMQEITRVRALEGEIARTIQAIRGVKAARVHIVLAEKGSFRRGDQKPSASVVIRAEGGFSAESAQSIRQLVAAAVPSLDASSVTVLDTNGHLLASAGEGANGAALMTASLEQQVASHVDDSIRKALAPYLGLGHFQTSVQAALDTDRRQTKETTYDPESRVERSVRVVRESGDSRNNRNDNATGVEQNIPQEQIQNRNGESSTEKTDRREELTNYEVNSMTVSTVSDGYSIKRLSIAVVIDQARLLQTAGTTPPPANFVDQQITKIRDLVATAAGLNTNRGDVINVTAVNFLDSAGADMEPVSAPWTDTLLRQSGSYANALAILAAVGLLIWFGLRPLLRDQNVKPAGTEVAIREAGEVATPNFIGGAESVGEGVQAVIGGPAAYADQMKTSLSDLRQRMRMPAKLRLEQMIEMDEERVAAVLKQWIHETASGREADPAKASAMPELKAA
What is the function of this protein?
The M ring may be actively involved in energy transduction (By similarity).  The flagellum is required to cause a persistent disease in a murine model of infection.
What are the official names of this protein?
Flagellar M-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FliF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.