PharMolix/UniProtQA huggingface dataset:
Protein: PRMA_HAHCH
Sequence: MSWLQVKVLTDEAGAAALEQIFEGLGALSVTMLDAADDPVLEPDLGTTPLWRNTQVVALFSADTSAEMVREQLERNQIAAADIECEVIEDRDWEREWMTHFHPMRFGSRLWICPSWGEPEDPNGVNLLLDPGLAFGTGTHPTTALCLTWLDSQQLQGKQVIDFGCGSGVLAIAALLLGADHATGTDIDPQALEASRDNAERNSVSEGLTLHFPEQMPEMQAEVVIANILANPLISLAPKLATLTLPGGSIALSGILKDQEEAVAEAYRNYFELDPTEYKEDWVLISGRRLPY
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRA_SHIF8
Sequence: MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRAVFLKQPEKSNAAYWRATHKLRLKLFGKIVKSRCLTAPALRKWIMRSGMAHIPQLKDYPTRFTSPTSRM
What are the official names of this protein?
Protein CbrA.
What is the protein family that this protein belongs to?
Belongs to the CbrA family.
Protein: VPC28_MYCTO
Sequence: MIVDTSAIIAILRDEDDAAAYADALANADVRRLSAASYLECGIVLDSQRDPVISRALDELIEEAEFVVEPVTERQARLARAAYADFGRGSGHPAGLNFGDCLSYALAIDRREPLLWKGNDFGHTGVQRALDRR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB28 (By similarity).
What are the official names of this protein?
Ribonuclease VapC28, RNase VapC28, Toxin VapC28.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: VGPCR_HHV8P
Sequence: MAAEDFLTIFLDDDESWNETLNMSGYDYSGNFSLEVSVCEMTTVVPYTWNVGILSLIFLINVLGNGLVTYIFCKHRSRAGAIDILLLGICLNSLCLSISLLAEVLMFLFPNIISTGLCRLEIFFYYLYVYLDIFSVVCVSLVRYLLVAYSTRSWPKKQSLGWVLTSAALLIALVLSGDACRHRSRVVDPVSKQAMCYENAGNMTADWRLHVRTVSVTAGFLLPLALLILFYALTWCVVRRTKLQARRKVRGVIVAVVLLFFVFCFPYHVLNLLDTLLRRRWIRDSCYTRGLINVGLAVTSLLQALYSAVVPLIYSCLGSLFRQRMYGLFQSLRQSFMSGATT
What is the function of this protein?
Receptor that signals constitutively via several signaling pathways including PI3K/AKT as well as mitogen- and stress-activated/MAP kinases.  Promotes host cell proliferation and survival, modulates cell migration, stimulates angiogenesis, and recruits inflammatory cells, both in expressing cells and in neighboring cells.  Maintains chronic activation of NF-kappa-B via interaction with host CADM1 (PubMed:29698475).
What are the official names of this protein?
viral G-protein coupled receptor, vGPCR, Protein ORF74.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: CD36_MOUSE
Sequence: MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDMLIEKTIKREVVLEEGTTAFKNWVKTGTTVYRQFWIFDVQNPDDVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPEDHTVSFVQPNGAIFEPSLSVGTEDDNFTVLNLAVAAAPHIYQNSFVQVVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNDTVDGVYKVFNGKDNISKVAIIESYKGKRNLSYWPSYCDMINGTDAASFPPFVEKSRTLRFFSSDICRSIYAVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFKTQVTGKIKLLGMVEMALLGIGVVMFVAFMISYCACKSKNGK
What is the function of this protein?
(Microbial infection) Acts as an accessory receptor for M. tuberculosis lipoprotein LprA, in conjunction with coreceptors TLR2 and TLR1; the lipoprotein acts as an agonist to modulate antigen presenting cell functions in response to the pathogen (PubMed:19362712).  Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and the internalization of particles independently of TLR signaling (PubMed:19864601, PubMed:23395392).  Mediates uptake of E. coli and S. aureus but has no effect on uptake of M. fortuitum (PubMed:16020694).
What are the official names of this protein?
Platelet glycoprotein 4, Glycoprotein IIIb, GPIIIB, PAS IV, PAS-4, Platelet glycoprotein IV, GPIV.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane. Membrane raft. Golgi apparatus. Note=Upon ligand-binding, internalized through dynamin-dependent endocytosis.
Protein: S35A2_HUMAN
Sequence: MAAVGAGGSTAAPGPGAVSAGALEPGTASAAHRRLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGAGLAAVVASCLSSGFAGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVATRGFFFGYTPAVWGVVLNQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHVDPLFALGAGLVIGAVYLYSLPRGAAKAIASASASASGPCVHQQPPGQPPPPQLSSHRGDLITEPFLPKLLTKVKGS
What is the function of this protein?
Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP (PubMed:9010752, PubMed:12682060).  It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars (PubMed:12682060, PubMed:11784306).  As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide (PubMed:30817854).
What are the official names of this protein?
UDP-galactose translocator, Solute carrier family 35 member A2, UDP-galactose transporter, UDP-Gal-Tr, UGT.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RL24_BURA4
Sequence: MNKIRKGDEVIVVTGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEEGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PHS_ROSS1
Sequence: MATRLSDAEIEERLGDLTGWTRQGNEIRKTFQLPSFPSAIAFVVNVAFLAEAAGHHPDIDIRWRKVTLSLTTHDAGGLTQKDFDLATQIDEIM
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: DICER_CHICK
Sequence: MKSPALQSLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFNKNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSSLEVTESWTKEKWSQEFSKHQVLVMTCHVALTVLRNEYLSLSNINLLVFDECHLAIQDHPYREIMKICEDYPSCPRILGLTASILNGKCDPAELEEKIKKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPYTDKSGLYGRLLRELDEALHFLNDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTSETETEPIVDDDDVFPPYVLRTDENSPRVTINTAIGHINRYCARLPSDPFTHLAPKCKTRELPDHTFYSTLYLPINSPLRASIVGPPMSCARLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSLQMLELITRLHQYIFSHILRLEKPALEFKPTEADSAYCVLPLNIVDDSSTLDIDFKFMEDIEKSEARTGIPSTQYTKEMPFIFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTATDAGVGVKSLPADFRYPNLDFGWKKSIDSKSFISIPSSSLVENENYCKHSTIVVPENAAHQGANRTSSAEKHDQMSVSYRTLLDESPSKLQIDVSAELAAINGVSYNKNLANGNCDLVNRDFCQGNQLNYCRQEIPVQPTTSYPIQNLYSSENQPKPSNECTLLSNKYLDGNANRSTSDGCPKMTVTTSTSTALNLSKDKVDSEKNTSSGYSSKTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYIVNQDKSNTDKWEKEETTKENLLANGKLDYDDDDEEDEDLMWRLPKEETDFEDDFLEYDQEHIKFIDSMLMGSGAFVKKISLSHFSTTDSNYEWKAPKKSSLGNVPFSSDFDDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDAGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKKTDWESTLCATGENCNSEQKNLSPNSVSACIVNSEPSLYKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFENFEKKINYSFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQMEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEMVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS
What is the function of this protein?
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing.  Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs.  SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.  Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance.  The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes (By similarity).
What are the official names of this protein?
Endoribonuclease Dicer.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LT_SV40
Sequence: MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
What is the function of this protein?
Isoform 17kT antigen targets host RBL2 for degradation and promotes cell proliferation.  Transactivates host cyclin A promoter through its J domain.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CLPP_CUSGR
Sequence: MPIGVPRVRFLYDEDTGQVWIDIYNRLYRERCLFLTHTINTKIGNQLAGLFIYLGIQDDPKDIFFFLNSPGGGIISGLAIYDSMQVVRPDTQTICVGLAASMACFLLVGGTITKRLAFPHARVMMHQPLSTFFETQTGDAVMEVDELLKMRENLIEVYAQRTGKPHWVISEDIERDVFLSPTEAKTYGLVDVVGVTLI
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid.
Protein: WFDC3_HUMAN
Sequence: MMLSCLFLLKALLALGSLESWITAGEHAKEGECPPHKNPCKELCQGDELCPAEQKCCTTGCGRICRDIPKGRKRDCPRVIRKQSCLKRCITDETCPGVKKCCTLGCNKSCVVPISKQKLAEFGGECPADPLPCEELCDGDASCPQGHKCCSTGCGRTCLGDIEGGRGGDCPKVLVGLCIVGCVMDENCQAGEKCCKSGCGRFCVPPVLPPKLTMNPNWTVRSDSELEIPVP
What are the official names of this protein?
WAP four-disulfide core domain protein 3, Putative protease inhibitor WAP14.
What are the subcellular locations of this protein?
Secreted.
Protein: C3H22_ORYSJ
Sequence: MDAYEATKVVFSRIQALDPDHAAKIMGLLLIQDHGDKEMIRLAFGPEALLHSVMAQARKELALLPPPPPPSSSSPTVPAAHSPFLLSRQNSGRGPAPSPSPLSASSPSSWAQAQPFSRSNGSVDEVVGAGEELISPANSGGGAAANAPPFFPRGGDVLLDDFQLQEQLAFLNEGGVNPSHPLQGFDGAECRSPGPGEGGGMFPYGLGWANGGPGHRRSASVNELCLGGGSSDGFGWKPCLYYARGFCKNGSSCRFVHGDDAAALTGAAMDAATAEQQQCQDFLLRSKSQRLGPAAFPYSPTGSLPGSPSAATKCLSLLLQQQHNDNQRAAAAAALMLGGSDEAHKFMGRPRLDRVDFASMMNPGSRQIYLTFPADSTFREEDVSNYFSIYGPVHDVRIPYQQKRMFGFVTFVYPETVKLILAKGNPHFICDARVLVKPYKEKGKVPDKYRKHQGDFSGCTTPTGLDGRDPFDLHQLGARMLQHSNSTNEMMLRRKLEEQQQAAELQQAIELHSRRLMDLQLLDLKNRAAAAVTTAMAMTIPTANAFGSSQPLATTMVESPPDSGEQLKGTGYFTEERKMVNGGGDKEESAGEASLNADSDQSLEHNLPDSPFASPTKSSVSAHQSFTTTDTGVVATSSCSASHVGISAGTNAGGGINHLRPSTLDIPSPRDFFSVSSRLASDHGAIGM
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 22, OsC3H22.
Protein: COBD_LISMF
Sequence: MILLFYTSSFILDCLLGDPYSWPHPIKAIGNLIKWLTIILRKIFHGKSLYFAGGLLFVLTVGMTGVVSWFILFLSAKIAYWLYVAVFVYLGYTTLAMTCLAKEARKIQRTLADGDLAAARVQVGMIVGRDTDKLTAEEISKATIETVAENTADGVIAPLFYLFIGGPVLALMYKAVNTLDSMVGYKNEKYRAIGFVSAKMDDIANFIPARLAWFFLVIASFILRYDGRASWQIGLRDRKNHTSPNCAYPEGAVAGALGITLGGTHEYFGETVIKPTIGSGNKPVSEKEISQTIHLLYTASTIAFIIFASIYLLLF
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMA_I49A1
Sequence: MYKVVVIIALLGAVKGLDRICLGHHAVANGTIVKTLTNEQEEVTNATETVESTNLNKLCMKGRSYKDLGNCHPVGMLIGTPVCDPHLTGTWDTLIERENAIAHCYPGATINEEALRQKIMESGGISKMSTGFTYGSSINSAGTTKACMRNGGDSFYAELKWLVSKTKGQNFPQTTNTYRNTDTAEHLIIWGIHHPSSTQEKNDLYGTQSLSISVESSTYQNNFVPVVGARPQVNGQSGRIDFHWTLVQPGDNITFSHNGGLIAPSRVSKLTGRGLGIQSEALIDNSCESKCFWRGGSINTKLPFQNLSPRTVGQCPKYVNQRSLLLATGMRNVPEVVQGRGLFGAIAGFIENGWEGMVDGWYGFRHQNAQGTGQAADYKSTQAAIDQITGKLNRLIEKTNTEFESIESEFSETEHQIGNVINWTKDSITDIWTYQAELLVAMENQHTIDMADSEMLNLYERVRKQLRQNAEEDGKGCFEIYHTCDDSCMESIRNNTYDHSQYREEALLNRLNINSVKLSSGYKDIILWFSFGASCFVLLAVVMGLVFFCLKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: APOL1_HUMAN
Sequence: MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
What is the function of this protein?
May play a role in lipid exchange and transport throughout the body.  May participate in reverse cholesterol transport from peripheral cells to the liver.
What are the official names of this protein?
Apolipoprotein L1, Apolipoprotein L, Apo-L, ApoL, Apolipoprotein L-I, ApoL-I.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein L family.
Protein: CDIP1_RAT
Sequence: MSNEPPPPYPGGPTAPLLEEKSGAPHTPGRTSPAVMQPPPGMPLPSADIAPPPYEPPGHPVPQPGFVPPHMNADGTYMPAGFYPPPGPHPPMGYYPPGPYPPGSYPGPGGHTATVLVPSGAATTVTVLQGEIFEGAPVQTVCPHCQQAITTKISYEIGLMNFVLGFFCCFMGCDLGCCLIPCLINDFKDVTHTCPSCKAYICTYKRLC
What is the function of this protein?
Acts as an important p53/TP53-apoptotic effector.  Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner.
What are the official names of this protein?
Cell death-inducing p53-target protein 1, LITAF-like protein.
What is the protein family that this protein belongs to?
Belongs to the CDIP1/LITAF family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TTCA_PECAS
Sequence: MSENQQTNQKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSFTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPQYLDNIGVEYKIVEENTYGIVKDKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKLKGMPPKLMSDDGKHIVIRPLAYCREKDIERFAEARQYPIIPCNLCGSQPNLQRQVIKDMLRDWDKRHPGRIETMFSAMQNVVPSHLADHALFDFKNIRHGSDVVDGGDLAFDREELPLQPAGWQPEEDDDASPITRLDVLEIK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPCS_ORYSI
Sequence: MAVYIAREATKLWRKVCAEIAVELQLLFEKWRLLLAGLVFQYIHGLAARGVHYLHRPGPLLQDLGFMALPELGQDKGYVSESVFTFIFISFLLWSFHPFIYHSKRFYTVLLWRRVLAFLVASQFLRIITFYSTQLPGPNYHCREGSKMATLPPPHNVLEVLLINFPRGVLFGCGDLIFSSHMIFTLVFVRTYHKYGSKRLIKILAWLMAIIQSLLIIASRKHYSVDVVVAWYTVNLVVFFIDNKLPEMPDRTNGSSLLPVTAKDKDGRTKEELHKLEKDCKMKEEFHKLLNGNTVDSTDRRQRVQMNGKHGEDINHTLSDATPNGT
What is the function of this protein?
Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis.  May play an important role in modulating plant programmed cell death (PCD) associated with defense (e. g.  toward Golovinomyces cichoracearum) by promoting sphingolipid metabolism and regulating ceramide accumulation (By similarity).
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase, Inositol-phosphorylceramide synthase, IPC synthase, Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1, Sphingolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: MPTB_METJA
Sequence: MERLIKLAEQIKDEELRKKVIEFLKNPKATHPGIVDTGISVEEAPASINWHHRYEGGLIEHTISVTKIALKMADVLEEVYGVEVNRDYIIAGALLHDIMKPYNYIRKEDGTFDHYDMFNLDHLTLAVAELYKRDFPIEVIKIVASHHGDHSPTRPNSIEAYIVHYADEADSKINDVAVRVCQARSRDLGISEQEIYKAVNPLKVYEVRSREGKLKTIEFLKDILKSIGIISEDEKKDENNESLENKESN
What is the function of this protein?
Cyclic phosphodiesterase that hydrolyzes the cyclic phosphate of 7,8-dihydroneopterin 2',3'-cyclic phosphate (H2N-cP) and converts it to a mixture of 7,8-dihydroneopterin 2'-phosphate (H2N-2'P) and 7,8-dihydroneopterin 3'-phosphate (H2N-3'P).  Is also able to utilize other phosphodiesters as substrates in vitro: hydrolysis of bis-pNPP and pNPPC produces nitrophenyl phosphate, and that of 2',3'-cAMP produces 3'-AMP.  ATP, 3',5'-cAMP, GTP, 3',5'-cGMP, and 4',5'-cFMN cannot serve as substrates.
What are the official names of this protein?
Dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase, H2N-cP phosphodiesterase, H2Neo-cP phosphodiesterase, 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase.
Protein: BIOD_RHOP2
Sequence: MTKPIVVTGTDTGIGKTVFAAALAGALDAFYWKPVQAGIEDETDRQAVLRLSGLPDARLLPEAYRLNTPASPHLAAEIDGVTIDAEALALPEIDGPLVVEGAGGLLVPLTRAITYIDIFARWRAPVVLCARTTLGTINHTLLSIEALRARAIPLLGVAFIGDENVESERVIVQIGRVPRLGRLPRLVEVTADALRAAFAQNFNTDDFLKDPAS
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3198_XANC5
Sequence: MTIAPTTLLLFAATALAELVGCYLPYLWLRKGGSMWLLLPTALSLAVFVWLLSLHPEASGRVYAAYGGVYIASALLWLWWVDGVTPTRWDLLGAACCLLGMAVIMFSPRSA
What are the official names of this protein?
UPF0060 membrane protein XCV3198.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REX_STRGG
Sequence: MATGRTHRPATRSRGIPEATVARLPLYLRALTALSERSVPTVSSEELATAAGVNSAKLRKDFSYLGSYGTRGVGYDVEYLVYQISRELGLTQDWPVAIVGIGNLGAALANYGGFASRGFRVAALIDADPAMAGTPVAGIAVQHTDDLDRIISDNGVSIGVITTPPGAAQQVCDRLVAAGVTSILNFAPTVLSVPEGVDVRKVDLSIELQILAFHEQRKAGEDSAAEDEGAPPMRATPASRKGPDGDMPAVMPA
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ALKEH
Sequence: MEGADDIVPMGEVVGLHGVRGWVKVYSHTEPREAILDYPHWYLRRDDGDWVPVERTAGRCQGKGLVAAFRDVEDRDRARAYIGLQIGVPRRDLPELPEGQYYWADLEGLAAYTTGGEPLGRVSHLFATGANDVLVLQGDRERLVPFVYGQTVRRVDLTAGRIELDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SACEN
Sequence: MADEQQRRAQDGGSARDRHVPVMMERTLELLAPALSKGPAVVVDATLGMGGHSEALLAAHPELTLVGLDRDPDALRLAGERLAPHSDRVHLVHAVYDEWAEALAGLSLSKVDGALFDLGVSSLQLDETDRGFAYAHDAPLDMRMDSGAPRTAADVLNTYSAGELTRVLREYGEEKFAARIAAAIVRERAKAPFDRSGRLVELLYDAVPAASRRTGGHPAKRTFQALRIEVNAELEVLGRALPAALDSLAVGGRMVVMSYHSLEDRMVKRAFAERAKSKTPVDLPVELPGHGPEIRLLTRGAELASDAETAANPRAASVRLRAAERIKEAV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.