PharMolix/UniProtQA huggingface dataset:
Protein: OAS2_HUMAN
Sequence: MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF
What is the function of this protein?
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response (PubMed:10464285, PubMed:9880569).  Activated by detection of double stranded RNA (dsRNA): polymerizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNASEL) leading to its dimerization and subsequent activation (PubMed:10464285, PubMed:9880569, PubMed:11682059).  Activation of RNASEL leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication (PubMed:10464285, PubMed:9880569).  Can mediate the antiviral effect via the classical RNASEL-dependent pathway or an alternative antiviral pathway independent of RNASEL (PubMed:21142819).  In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation (PubMed:21142819).  May act as a negative regulator of lactation, stopping lactation in virally infected mammary gland lobules, thereby preventing transmission of viruses to neonates (By similarity).  Non-infected lobules would not be affected, allowing efficient pup feeding during infection (By similarity).
What are the official names of this protein?
2'-5'-oligoadenylate synthase 2, (2-5')oligo(A) synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS, p69OAS / p71OAS.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: IF2_DESVH
Sequence: MTENKTKVKDLAAELGVTTKELGQVLKDMNISAKTSTSVIAQEDLPRIKERVQAQRDGGARKEGNPDVIVRRRHRDGDRASARAEAKAPEQEATAAMPETSAPERAEEADKPAVAKPAKAPETEAHARARKEPQAEPVKARIIRRPDEPAPVAKVVEAAPAETPAPEAPAVKATVTAEAAPAKTVEPESERPQADKPATARVVRPATPDASAVPDGTSSAPTLPVRSAEPSDTVERADADADGDDDDAQQRRRKKKRRQPEAVVPQVRVISRPDPAAVAQQQMQQQAAQQQREAGGYRPGGQRPEGGYRPEGQREGGYRPEGQREGGYRPGGAPRPEGGYRPGGPRPEGGYRPGAPRPEGGYRPAGGPRPEGQREGGYRPGAPRPEGGYRPAGGAPRPEGQREGGYRPAGGPPRPGGAPRPGGFGGAPGGMPVPGADGRGDQSKKKRQKGRRTVDFQADGPRGRSDDDVMRGPRGRGKRGKKDVRPAATQPLKAVKRKIKVDEAIRVADMAHQMGLKANEIIKVLFGLGVMATINQSLDIDTATVVAGEFGYEVEKVGFSEDDYLVPKEEDAPETLVTRPPVVTIMGHVDHGKTSLLDAIRKSNVTAGEAGGITQHIGAYHVTTKKGEIVFLDTPGHEAFTAMRARGAQITDLVVLVVAADDGVMEQTREAVNHSKAAGVPIMVAVNKMDKEGANPDRVIRELSELGLVAEDWGGDTIFAKVSAKTREGLDELLELIAIQAEILELKANPDKAARGHVVEAKLDKGRGPLATVLVQEGTLRQGDAFVCGVFAGRVRAMFDDQGRKVKEAGPSTPVEVQGFDGVVEAGEEFVSVADDKVARRIAESRAVKQRERELAKESKVTLETFLSRRADAAEALTLNLVLKADVQGTLEAISEAVRKLSTEKVKINIIHGGAGAITESDILLASASDAIIIGFNVRPTSKVKDIAEQENVDIRFYDIIYKLVDEIKSAMAGMLAPVQREVYLGQAEVRETFSVPKIGVIAGCHVADGKVTRNAGVRLLRDGVVVYTGKITSLKRFKDDVRDVQKGYECGMGLENFNDIKVGDVIEAFEMVEEAATL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGDG3_ORYSJ
Sequence: MAASSSSSSSMASPRGRSIRETVLETVAAYHQQQRMRRKFRKSLSYAGELSSAGRARGEGGASSSASTTSLCGPDEDDEPFWEEEEGTVELVQLGANRAKNVLILMSDTGGGHRASAQAIKDPFRIEFGDDYRVFVKDLCKDHAGWPLNNMESSYKFMVKHVQLWKVAFHTTSPRWVHCFYLAALASFYAKKVEAGLKKYKPDIIISVHPLMQHIPLWVLKWQGLQNRVVFVTVITDLNTCHPTWFHADVNRCYCPSEEVAKRAALDDLQPSQIRVFGLPIRPSFCRAVLVKDDLRKELELDPELPAVLLMGGGEGMGPVKKTAKALGESLFDKELGKPIGQLIVICGRNKTLSSSLQALEWKIPIKVRGFETQMEKWMGACDCIITKAGPGTIAEALIRGLPIILNDFIPGQEVGNVPYVVDNGAGVFSKSSRETAKLVARWFGPDSDELKRMSEKALKLAQPEAVFDIVRDIHELSREQGVISQISSSLTSSFFIPSPETTPIQLM
What is the function of this protein?
Involved in the synthesis of the major structural component of photosynthetic membranes.
What are the official names of this protein?
Probable monogalactosyldiacylglycerol synthase 3, chloroplastic, OsMGD3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane.
Protein: NRDC_HUMAN
Sequence: MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTTLNLLPYHKIVK
What is the function of this protein?
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.  Is a critical activator of BACE1- and ADAM17-mediated pro-neuregulin ectodomain shedding, involved in the positive regulation of axonal maturation and myelination.  Required for proper functioning of 2-oxoglutarate dehydrogenase (OGDH) (By similarity).
What are the official names of this protein?
Nardilysin, N-arginine dibasic convertase, NRD convertase, NRD-C, Nardilysin convertase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: HPAA_HELPJ
Sequence: MKTNGHFKDFAWKKCFLGASVVALLVGCSPHIIETNEVALKLNYHPASEKVQALDEKILLLRPAFQYSDNIAKEYENKFKNQTTLKVEEILQNQGYKVINVDSSDKDDFSFAQKKEGYLAVAMNGEIVLRPDPKRTIQKKSEPGLLFSTGLDKMEGVLIPAGFVKVTILEPMSGESLDSFTMDLSELDIQEKFLKTTHSSHSGGLVSTMVKGTDNSNDAIKSALNKIFASIMQEMDKKLTQRNLESYQKDAKELKNKRNR
What are the official names of this protein?
Neuraminyllactose-binding hemagglutinin, Flagellar sheath adhesin, N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit, NLBH.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MCPA_TRIVH
Sequence: MRSVLSLALLAVNVVTAAVVAPFDYSGYKVIRVPTQKDNVKEVQRIITDLNLDTWKYPKSEGQNADIVVPPSQISSFMERISGMNIEMMHEDLGLSIRNETSFEAYSAGYAPDINWFKSYHSYQDHLSYLQDLQGLFRTRSEYVDAGKSHEGRTIPALHIWGSGGKNSKPAIIFHGTIHAREWITTMVTEYMAWSFLSQYNKNADITSIVDNFDIWIFPIVNPDGFAFTQTSNRLWRKNRQPNPNARCPGRDLNRNYPYQWVGPGSSSNPCSDTYRGAQPGDGTEIKVHIANMKKIAANKGIAMFVDWHSYGQLFMSPYGYSCTARPPTDARHQELSRIFAQALKAVHGTPYKTGPICNTIYQVNGDSVDYALEVLKVKLSLTAELRDTGARGFVLPADQIIPSGEETLAGTVAMLKAVIQG
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Probable metallocarboxypeptidase A, MCPA, Carboxypeptidase M14A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_LACLS
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIPNPEGNRTTPSVVAFKNGEIIVGDAAKRQAVTNPETIISIKSKMGTSEKVSANGKEYTPQEISAMILQNLKATAESYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGNNKLGGDDFDQKIIDWMVAEFKKENGIDLGQDKMALQRLKDAAEKAKKDLSGVTTTQISLPFITAGAAGPLHLEMALTRAKFDELTHDLVEATRQPVRQALSDAGLSTSDIDEVLLVGGSTRIPAVVELVRHETNKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIKSNSGLSDEEIDKMMKDAEANADADAKRKEEVDTRNEADALVFQTEKTLKDLEGKVEEAEVKKAEDAKEELKKALEGEDIDDIKAKSEALSEIAQNLAVKLYEQANAAQGEAGEATDAQEGPKDANTFDGDFEESK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EX7L_ECO55
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRVQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_STAA2
Sequence: MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPRX_HUMAN
Sequence: MPGSEDLRKGKDQMHSHRKRTMFTKKQLEDLNILFNENPYPNPSLQKEMASKIDIHPTVLQVWFKNHRAKLKKAKCKHIHQKQETPQPPIPEGGVSTSVGLRNADTLPRLPNAAHPIGLVYTGHRVPSFQLILYPNLKVPANDFIGHRIVHFGCCRDPNIYCLYPILESQVCAPSFHSGSPACSSNQSRER
What is the function of this protein?
Transcription factor that acts as repressor.
What are the official names of this protein?
Divergent paired-related homeobox.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIR1_MYCBO
Sequence: MPPTVIAEPVASGAHASYSGGPGETDYHALNAMLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIPTQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase R1 subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: H2AO_CHITH
Sequence: MSGRGKGGKVKAKAKSRSSRAGLQFPVGRIHRLLRKGHYAERIGAGAPVYLAAVMEYLGAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTESKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A, orphon.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: URK_STAA9
Sequence: MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWP1_CANAL
Sequence: MKVSTIFAAASALFAATTTLAQDVACLVDNQQVAVVDLDTGVCPFTIPASLAAFFTFVSLEEYNVQFYYTIVNNVRYNTDIRNAGKVINVPARNLYGAGAVPFFQVHLEKQLEANSTAAIRRRLMGETPIVKRDQIDDFIASIENTEGTALEGSTLEVVDYVPGSSSASPSGSASPSGSESGSGSDSATIRSTTVVSSSSCESSGDSAATATGANGESTVTEQNTVVVTITSCHNDACHATTVPATASIGVTTVHGTETIFTTYCPLSSYETVESTKVITITSCSENKCQETTVEATPSTATTVSEGVVTEYVTYCPVSSVETVASTKVITVVACDEHKCHETTAVATPTEVTTVVEGSTTHYVTYKPTGSGPTQGETYATNAITSEGTVYVPKTTAVTTHGSTFETVAYITVTKATPTKGGEQHQPGSPAGAATSAPGAPAPGASGAHASTANKVTVEAQATPGTLTPENTVAGGVNGEQVAVSAKTTISQTTVAKASGSGKAAISTFEGAAAASAGASVLALALIPLAYFI
What is the function of this protein?
Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization.
What are the official names of this protein?
Yeast-form wall Protein 1, GPI-anchored protein 24, Thiol-extractable peptide 1, flocculation protein 1.
What is the protein family that this protein belongs to?
Belongs to the flocculin family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=In yeast cultures, is linked covalently to glucans of the wall matrix, but, as cultures approach stationary phase, accumulates in the medium and is extractable from cells with disulfide-reducing agents. Removed from the cell wall by proteolytic cleavage by SAP9 and SAP10.
Protein: YEEE_ECOLI
Sequence: MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIVKNNRMFYALLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYIFGLGIVLAGGCATGTWYRAGEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVAVLLVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLSEATGRMFGLGITSPTANILQFLVAGDMKYINWGVFLVLGIFVGSFIAAKASREFRVRAADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASWLVYVRPQRKARLATAAAN
What are the official names of this protein?
UPF0394 inner membrane protein YeeE.
What is the protein family that this protein belongs to?
Belongs to the UPF0394 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INLI_LISMF
Sequence: MKKKFSIVIISVLLLGYLAPFDTLLVGADETTVTEDTTVKTAETETATEATESESGSDNEKAEEPKEAEASKETTEKEEKAKTKEPASNIKTEINTDKSQLKQTNLKAVVPAGSTYNSLFPDDNLAKKLAVIITGNAAATGNESVDSAALLAISQLDLSGETGNDPTDISNIEGLQYLENLTSLNLSENNISDLAPIKDLVNLVSLNLSSNRTLVNLSGVEGLVNLQELNVSANKALEDISQVAALPVLKEISAQGCNIKTLELDNPAGAILPELETFYLQENDLTDLTSLAKLPKLKNLYIKGNASLKSLATLKGATKLQLIDASNCTDLETLGDISGLSELEMIQLSGCSKLKEITSLKDLPNLVNITADSCAIEDLGTLNNLPKLQTLILSDNKDLTNINAITDMPQLKTLALDGCGITSIGTLDNLPKLEKLDLKENQLTSISEINDLPRLSYLDVSVNYLTTIGELKKLPLLEWLNVSSNRLSDVSTLTNFPSLNYINVSNNVIRTVGKMTELPSLKEFYAQNNNVSDISMIHDMPNLRKVDASNNLITNIGTFDNLPKLQNLDVHSNRITNTSVIHDLPSLETFYAQNNLITNIGTMDNLPELTYVDLSFNRIPSLAPIGDLPKLEILKVTDNYSYLRSLGTMDGVSKLRNLELQNNYLNYTGTEGNLSALSDLTNLTELNLRDNGYISDISGLSTLSRLIYLNLDSNKIKDISALSNLTTLQELTLENNQIEDISALSDLDNLNKLALSKNKIIDISPAANMVNRGASVTASNQTYTLPTVLSYQSSFTIDNPVVWYDGTPLAPSSIAHSGTYKDGEITWTNMTAASSSTEFNFNRLKDGLTFSGTITQPYKSAVKVTANAEQTYTIGDTISEEQFLKDVNAKSSDGAPVTSDFATVVDLNTFGEYEVTLTSEKDGIQGDSCKVIVKVLHGAPVISADQTINYDKHATITEKQFLEDVHASTDLNTAITTNFSTAVNLNKGGDYTVALNSENEDGVKAETVYVTVTVDKDPAPIISAKTDITYDKFSKKTEAAFLDDIDADTNDGSIITSNFATAVNLDKAGDYTVTLNSINSDGVASTPTAIIVHVEKEKIATISANTAQQYEKYAEINETQFLKDVHASINASPTTAVLESDFETVVKLDVPGTYTVTITATNEDGGVSAPKEVSVIVKKLPAPEITADKEITYPKFDEVSEAEFLSDIHATINEKNVTITSNFSADVNLNKAGDYTVTLNATNEDGVKATPVEVIVHVQQGERPVITADATISYDKFANITEAKFLEDIHATSSDGQSSTVITSNFETATNFKTAMSYTVTLNAVNEDGISAEPVAVTVTINKEPAATLKADAEVSYAKNEAVTESDFFKDVHLEGAEAPSTAKATSNFDSVVDRSKTGDYTVTINATNEDGAVSTPIEVIVHIGAESAPVITANAEVKYNKHEQTDERRFLYDSDAKIDEANVEIKTDFAEKVDINKVGTYTVTLTATNEDGQAANPVEVSVIVSDAAAEKVNVKYVDENGAEISAAETLTGNLDDAFSIDAKSIAGYKCDATLSGVFSTVEQTVVFHYKAIEPGVVTIKYEDANGKAVAEDKQITGEVGDDFEAEAQTVSGYSCRAIASGKITEEPQTITFTYTTATPSKKSGEITVQYVDESGKKLADSKKVTGDIDDSYSVEAKAIDGYSVVGDDSAKGVFTEKSQTVTFKYKKNTQVSKDEPKVKGKTNQPPSADTKLKVDNNTLPATGDTENMALAVLIGFNMLLVASIFLFRKPKTNQ
What is the function of this protein?
A role in virulence could not be demonstrated.
What are the official names of this protein?
Internalin I.
What is the protein family that this protein belongs to?
Belongs to the internalin family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: NAT_SACS2
Sequence: MELAEKDKGRDFTLRNARMDDIDQIIKINRLTLPENYPYYFFVEHLKEYGLAFFVAIVDNSVVGYIMPRIEWGFSNIKQLPSLVRKGHVVSIAVLEEYRRKGIATTLLEASMKSMKNDYNAEEIYLEVRVSNYPAIALYEKLNFKKVKVLKGYYADGEDAYLMARPL
What is the function of this protein?
Displays alpha (N-terminal) acetyltransferase activity.  Catalyzes the covalent attachment of an acetyl moiety from acetyl-CoA to the free alpha-amino group at the N-terminus of a protein (PubMed:17511810, PubMed:23959863, PubMed:25728374).  NAT is able to acetylate the alpha-amino group of methionine, alanine and serine N-terminal residue substrates, however it has a preference for Ser-N-terminal substrates (PubMed:17511810, PubMed:23959863, PubMed:25728374).
What are the official names of this protein?
N-alpha-acetyltransferase, NAT, Amino-terminal acetyltransferase, N-terminal acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_SALA4
Sequence: MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL3_BURL3
Sequence: MMSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVEAGEILKEFRIDAAKAAELSNGAVVGVDLFEVGQKVDVQGVSIGKGYAGTIKRYNFSSGRATHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDAERKLLLVKGAIPGAKGGKVFVTPAVKTKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS11_SYNAS
Sequence: MAKQVRKTGKKKEKKNIPEGIAHIQSTFNNTIITITDPIGNVIAWSSSGMQGFKGSRKSTPFAAQMAAEDCVKKAKEHGLRKVQVYVKGPGSGRESALRSLQAAGLTISLIRDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HEMH_MICAN
Sequence: MGRVGVLLLNLGGPERLEDVRPFLFNLFSDPEIIRLPIKGLQKPLAWLISTLRASKSQENYRQIGGGSPLLKITEAQATALQQRLKEMGREVSVYIGMRYWNPFTEEAIERIKRDHIKKLVILPLYPQFSISTSGSSFRVLEEMWQQDPYLRLTEYTLIPSWYDHPTYLSAMADLIARELEQCPNPDQVHIFFSAHGVPQSYVEEAGDPYQRQIEECTRAIMRTLNRPNQYTLAYQSRVGPVEWLKPYTEDALKELGEQGIKHLLVVPISFVSEHIETLQEIDIEYREVAEEAGIEHFQRVPALNTHPMFIESLSQLVVKSLEEKPTTFEQITHPKANMKMYPQERWEWGMTTAAEVWNGRLAMIGFLAIIIELITGQGPLHFVGLL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_CYTH3
Sequence: MASQFQAYFKLTKFRLTSTVAFSSGMGYILAERGQVDWLNLVLFLIGGFSITVSANIINQIIERESDKLMKRTASRPLPEGIITVQQAIITSALFLIAGTVILAVYSTLNALILSLISLVIYSFIYTPLKTVSPIAVFIGAFPGAFPPMIGWIAVTGEYGWEPGVLFAIQFLWQFPHFWAIAWVLDEEYKKAGIKLLPTKDGRSKHTATIIMTYTLCLLPLGFLPYLFGMSGITSAYIALACGILFFFQTMYLWKECSVKAALLLMFGSFLYLPIVQIAFVLDKIY
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.