PharMolix/UniProtQA huggingface dataset:
Protein: PRTX_DICCH
Sequence: MEKNLSSRDDDALHSLSAPSSSYNSIYDLLHYHERGNGLTINGKPSYSIEDAGDQITRDNVSWNGANVFGKSANLTFKFLQSARSTPDGDTGFVKFNAAQISQAKLALQSWADVANVTFTEVTGNQSANVTFGNYTRDSSGRLDYGTQAYAYLPGSGSASGTTWYNYNVDNIRSPDTMEYGRQTLTHEIGHALGLNHPGDYNAGEGNPSYSDVTYAEDTRQFSIMSYWSEKNTGGDFKGHYAAGPMLDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATSSSKALIFSAWDAGGNDTFDFSGYSNNQRINLNDGSLSDVGGLKGNVSIAEGVTIENAIGGSGNDLLIGNNADNTLRGGAGDDVLFGGSGADRLYGGSGRDTFVYTAASDSKVAAPDWLLDFQTGADKIDLSALNTGNNLHFVNQFSGSGGEIMLNWDASANTSNLYLNLDNNTSPEFLVKIVGQVSQTADFVV
What are the official names of this protein?
Serralysin C, Secreted protease C, ProC.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_LACP3
Sequence: MANQIIDQAKVNMGKTEESLQRELGNIRAGRANASLLNQITVEYYGAPTPLNQMAAITIPEPRVLQVSPYDKSSLKNIETALNASDLGINPANDGDVIRLVIPQLTGERRKEIAKEVGKYSESAKIAIRNIRREGLDKLKRQEKDGDITEDDLHRLEKDMQKATDDATKRIDEIAAAKEKEITEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_SHESH
Sequence: MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPMMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMDLVAERLRGETASYDIKDSEGSILVEKGRRITARHIRQLEKTNTTELEVPVDYISGKISGQDYIDPDTGEVLVSANAEISLEDLAKLSLAGIKEISTLYINELDNGAYMSDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIDDDEGTGILSKEDIVAVMKNIITIRNGNDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVVTDQVDYLSAIEEGRYVIAQAIVDLDADGRMMDELIACRHKGDSTFMGAGDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVAAKRGGYVDYVDASRIVVKVNESELTPGEAGIDIYNLTKYTRSNQNTCINQRPCCSMGDPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAMEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHVGQAKKDLSEEFQILEEGVYGRARNLLLNAGFTEDQLATIPRSQLLVQTIDDEAKQTELEQLAEQHDELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPVEDMPYDENGNPIDIVLNPLGVPSRMNIGQVLEVHMGAAAKGIGDRITAMLEEQRELAELRGYIKEVYELGEEVQQRVDIDSFTDDEVLRLAKNLKGGVPTATPAFDGAKEKEIKEMLALAGLPTSGQRRLFDGRTGDEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTHMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PNP_DINSH
Sequence: MFNQVKKTMEWGEDTLTLETGKIARQADGCVIATYGETSVMAAVTYARSQKPGQDFFPLTVHYNEKYYAAGKIPGGFFKREARPTEKETLTSRLIDRPIRPLFVDGFKNEVLVICTVLSHDLENDPDIVAMIAASAALTISGVPFMGPIAGARVGYEDGEYVLNPVVDDMHDLRNNPDQRLDLVVAGTKDAVMMVESEAYELSEAEMLGAVKFGHEQMQPVIDLIIELAETAAKEPFDFQPADYSELYAKVKAAGEDQMRAAFAITDKQERVTAISAARDAILATLSDEEQTDPNLGSALKKLESSILRGDVVKNGRRIDGRALDTVRPIQSEVGILPRTHGSALFTRGETQGLVVTTLGTGDDEQFIDALHGNFKSNFLLHYNFPPYSVGEVGRFGPPGRREIGHGKLAWRALQAVLPAATDFPYTIRLVSEITESNGSSSMASVCGGSLSMMDAGVPLKAPVAGVAMGLILEEDGSYAVLTDILGDEDHLGDMDFKVAGTEEGITSLQMDIKVAGITPEIMEKALEQAKAGRLHILGEMSKALSEGRSQFSEHAPRIETMQIPTDKIREVIGSGGKVIREIVETSGAKVDINDDGIIKIASANGEAIKKAYEMIHSIVAEPEEGKVYTGTVVKIVDFGAFVNFFGKRDGLVHVSQIENRRLNHPSDVLKEGQEVKVKLLGFDDRGKVRLSMKVVDQETGEEIKKEAPAD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_WIGBR
Sequence: MNFGNKIKCSICKKKIFLREKNLFFPFCSKKCKIIDLYQWISGKYKLF
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: FOLD_SALPB
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTLQACIEYHDPQGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL114_PLAVT
Sequence: MCGAHFVAIALLVAAGCQTAAEFDQDDIQQTSKDDSMASIDLLQSRNLRESRDSKDDLLSAGDEERTPPFPSGVLKEPKVADSTMAAANVMRTEGEASAIKAASKNLNQLKSNKPQRIAPASRSVAGQVLHSSPDSDKSLVSVENEQLLVLAKRRRTKHPTAMMTNAVRSAEQHDYRLAPTESSTLPAQASDGQLSKQLITQKVLQLDKKKHVDESLWREELMTVDEVLHLLETFDKPAHPTAVNVHEANAIGIATKKLNYLRRNKRKRIAPTSNNVVGQVPHAQPDPDKSPVLVAKDIPSVLAKRLRTDHPTAIMENAARFVTQHNYRLAPTGPSTIIAATPNSQLKYHLPGQKALHLDKNEHAGDLKSLRNEESHTIEHILHLRERNDKSAHTTAENHQSVPEDWNTVSAKGPKLLSKDSINEKVKKVHAAFVEAFNLPFHQYPEETAMMLKLVQRKTKSSPNNGETYDAFMYMAELQQHSSHLRKLLGPDLKMLLGTDKTVLPIKLENLQEAYNVKLVIMYDLFFEFCHDRKDLVEGLPRKPKPNQWILKLST
What is the function of this protein?
Secreted effector that partially suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 114.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: AKCL2_MOUSE
Sequence: MENIPTVGLGTWKASPGEVTDAVKLAINLGYRHFDCAYLYHNESEVGMGISEKIKEGVVKREDLFVVSKLWCTCHKKSLVKTACTNTLEALNLDYLDLYLIHWPMGFKPGEKDIPLDRNGKVIPSHTSFLDTWEAMEDLVFEGLVKNLGVSNFNHEQLERLLDKPGLRVRPITNQIECHPYLNQKKLIDFCHKRNVSVTAYRPLGGSGGGFHLMDDTVIRKIAKKHGKSPAQILIRFQIQRNLIVIPKSVTPSRIRENIQVFDFELTEKDMEELLSLDKNLRLATFPTTENHQDYPFHIEY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.
What are the official names of this protein?
1,5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E1, Aldo-keto reductase family 1 member E2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSX_RHOJR
Sequence: MSASTETHHASEAAVPTAPRPRPGLGTKNGRLHQVPHIAGLILGVFSVLVFLWSISPVLRYYVHVPREYVDTYYFDAPDTSLSWALVVALLAAALASRKRIAWWLLTIYLVLFLITNVIVSITDKNVNAMAAAVVQVVLIGILIAARPEFYTRVRRGAGWKALGVLIVGLAIGTLLGWGLVELFPGTLPQNERFLWALNRVTALAAADNEQFTGRPHGFVNTLLGLFGAIALLAAVITLFRAQRSHNALTGNDESALRGLLLQYGADDSLGYFATRRDKAVVFAPSGKAAITYRVELGVCLASGDPIGDPEAWPHAIEEWQALASQYGWATAVMGASETGATAYNKAGLTVLQLGDEAILRTREFNLSGRDMRQVRQAVTRVRRQGVTVRIRRHRDVPAEEMAETIRLADAWRDTETERGFSMALGRLGDRLDGDCLLVEAVAEDGEIDGILSLVPWGPTGVSLDLMRRKPTSPNGVVELMVSELATTSDQFGITKVSLNFAVFRSVFEEGSRIGAGPILRIWRSILVFFSRWWQLEALYRSNVKYQPEWVPRFLCFEDNRELLRVGFASAVAEGFVTLPRFGRSGTRDALEHTGTHAAVPAALVAAEGLHSDGSAPGEGLAPTATGPKRPEQVRVRLDKLAGLAEQGIDPYPVAYPPSHTVTEAVESPEGTTVRIAGRLLRIRDYGGVVFAVVRDWSGDIQILVDEARVGTDRIRAFAAEFDLGDLVEVAGVIGYSRRGALSLLANEWRMTGKCLHPLPDKWKGLSDPETRVRQRYVDLAINSDARRLLEARSAVVKSLRDSLGGRGFLEVETPILQQVHGGANAAPFLTHINAYNLDLYLRIAPELYLKRLCVAGMEKVFEIGRVFRNEGVDFKHNPEFTILEAYEAHSDYEKMMVLCRELIQTAAIAAYGREIIMRPGPDGALVEVDISGEWPVKTMHQAVAEKLGVDVSPETPLTELQRLCDEHEIPYQSTWDAGAVAQEMYEHLVEDYTEFPTFYTNFPTSMSPLTRPHPTIPGVAAKWDLVAWGVELGTAYSELTDPVDQRNRLTEQSMLAAGGDEEAMELDEDFLQALEHAMPPTGGLGMGVDRVVMLITGGSIRETLAFPLAKPRQ
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ULAE_ECOUT
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: HSCA_COLP3
Sequence: MALLQIAEPGQSTVPHEHRLAAGIDLGTTNSLIASVQSGNASTLSDDQGRDILPSIVSYQAGNVLVGQTAQALSIEDAQNTITSAKRLIGRSLKDIQSKYPSLPYEFCGDENHPEIMTRQGAVNPVQVSAEILKSLNLRAQAALGGELTGVVITVPAHFDDAQRQSTKDAAKLAGVSVLRLLNEPTAAAVAYGLDSGQEGVIAVYDLGGGTFDISILRLNKGVFEVLATGGDSALGGDDFDVVLVDYLVEQAGLVRPLSPSLERQLMQQACFAKEQLTTKEEVDITISLDSDSDWKTSLTKAQLNKLISSLVNKTLRACRRTLKDADITIDEVIEVVMVGGSTRVPLVRSEVEKHFNKTPLTSIDPDKVVAIGAAIQADVLVGNKPDSDMLLLDVTPLSLGLETMGGLVEKVIPRNTTIPVAKAQEFTTFKDGQTAMAVHVLQGERELVEDCRSLARFELRGIPAMTAGAAHIRVTFKVDADGLLSVSAMEKSSGVESSIEVKPSFGLDDNQISQMIKDSMSNAADDMQARMLKEQQVEASRVIESVQAALLADSKLLNSDEITVIENAIKSLAQVSQGQEIKAIENALDKLNDSTAIFAERRMDSSISEALAGQAVDKI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ARLY_STRGC
Sequence: MANHKLWGGRFEASLEGWVEEFGASIGFDYRLAPYDLEGSLAHVKMLGQTGIIAPEEAAAIQAGLEKLLARYESGELEFDVRNEDIHMNMEALLTEKIGPVAGKLHTARSRNDQVATDMHLYLKDQLGQIADKLLNLRQVLLDLAEEHVETIMPGYTHLQHAQPISFAHHLLAYYQMFSRDSQRFAFNLEHTDLSPLGAAALAGTTFPIDRELTADLLGFKGIYHNSLDAVSDRDFILEFLSNSSILIMHLSRLCEELINWCSYEYGFVSLSDTFSTGSSIMPQKKNPDMAELIRGKSGRVYGHLFSLLTVMKSLPLAYNKDLQEDKEGMFDTVDTIQKSLDIMAGILSSMTVNKEKMLVSTQQDFSNATELADYLAKKGLPFREAHEIVGKLVLECSKAGYYLQDIPLSRYQEVSSLIEEDVYQALESQTAVQKRNSLGGTGFEQIRQELERAKKDLNNK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDB_METMA
Sequence: MTSELPPQIQNQIAQLQQVQQQVQALSMQKSQIEAMQKESKMALEELERLADDAVIYRSVGELVIKTTKEESVSKLKDREETLSLRLQSISRQEERLTARFKQLQEQIQQALGPRAQ
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1108_STRMK
Sequence: MSTVTPSAPTLIIVSGLSGSGKSVALKTFEDQDYYCSDNLPINLLPDFVRSLLANHDGSAPRRLAVGIDVRGQADLSQLGDWRQLAADAGVDVKVLFFEASDETLLKRYADTRRRHPLSQLGLSLPEAIARERELTAPLRREADAVIDTSSLNVHQLRRRIITEFTMDHATGLSLLFESFAYKRGVPAEADFVFDARVLPNPHWDPDLRALSGREPGVRDYLEAQPDVQRYLAQLMDFLDTWLPKLGDGTRSYVTVAFGCTGGKHRSVFLAERLARHAREMGWEDVATYHREQD
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Smlt1108.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: TSAD_THET2
Sequence: MWVLGIDTSCDDTGVGLVRDGKVVVNLVASQVRLHEAFGGVVPELASREHLKALPLLVERALAEAGLRPKDLDLVAATRGPGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAAWPEGLPPPFLALVASGGHTHLYEVLDLGRYRLLGATRDDAAGEAFDKVARLLGLGFPGGPEVERLAEEAEEAIPFPVPLRGQEGYDFSFSGLKTKALHLVEKGLPKAALAKGFQEAAIAHLAEVVLKAAKDTGHRVLLVAGGVAANRALQERFKEAGLEVHFPPRGLSQDNGAMIALAAWRRHQRGFPPSPLSLGATAYWPLEEA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGTC_MYCTO
Sequence: MCRHLGWLGAQVAVSSLVLDPPQGLRVQSYAPRRQKHGLMNADGWGVGFFDGAIPRRWRSAAPLWGDTSFHSVAPALRSHCILAAVRSATVGMPIEVSATPPFTDGHWLLAHNGVVDRAVLPAGPAAESVCDSAILAATIFAHGLDALGDTIVKVGAADPNARLNILAANGSRLIATTWGDTLSILRRADGVVLASEPYDDDSGWGDVPDRHLVEVTQKGVTLTALDRAKGPR
What is the function of this protein?
Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine (By similarity).  ERG is one of the major redox buffers which protects bacteria against redox stressors and antibiotics; loss of ERG or mycothiol (MSH, the other major redox buffer in this bacteria) leads to respiratory alterations and bioenergetic deficiencies that negatively impact virulence (PubMed:26774486).
What are the official names of this protein?
Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Gamma-glutamyl hercynylcysteine S-oxide hydrolase.
Protein: NEURM_HIRME
Sequence: MALLNKLLCFALVFMIFGEFVTPDCYEDWSRCTPGTSFLTGILWKDCHSRCKELGHRGGRCVDSPSKHCPGVLKNNKQCHCY
What are the official names of this protein?
Neuromacin.
What is the protein family that this protein belongs to?
Belongs to the macin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRCB_RHIL3
Sequence: MIQAILVAFGGAIGSVLRYYVGQWALRLMGSAFPWGTLAVNVVGCFVIGVFAELIARKFDASVELRLLLITGFLGGFTTFSAFSLDAISLFERGEAVAGGIYIAASVGLSMAAVIAGLAVMRALA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_NOCFA
Sequence: MSGDIIDELTWRGLIAQSTDLDALRAALAAGPLTLYAGFDPTAASLHAGHLVPLLALKRFQRAGHRPIVLAGGATGLIGDPRDVGERTMNSSDTVAEWARRIRSQLERFVDLDDSPTGAVIVNNMDWTGPLSAVDFLRDIGKHFSVNVMLARDTVKRRLEGDGMSYTEFSYMLLQANDYVQLRRSFGCRLQVGGSDQWGNIIAGVELNRRLDGESVHALTVPLVTSADGKKFGKSTGGGSLWLDPEMTSPYAWYQYFVNTADADVVRYLRWFTFLDREELAELERATAERPHAREAQRRLAAEMTTLVHGEQHTRAVQLASQALFGRGDLRELDEATLGAALREAAGEGEVARVTPGEPATIVDLLVATGLAESRGAARRTVNEGGAAVNNQKIADPDWTPADGDYLHGRWLVVRRGKRNMAGVLRDGN
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_MICAN
Sequence: MVASLSYQNGQKARSHPLLSLAGLIELPPSPLFGTDGIRGQVGELLTAPLALQIGFWAGQVLKNQAGVTKPIIIGQDSRNSSDMLANAITAGLTWAGIEVWQLGLCPTPCVAYLTRESEAMGGIMISASHNPPEDNGIKFFDSSGLKLSGTLAGQIEAGLRGNLELADNSVNWGKATFCPELIQKYYQAVIASVGTDINLSGLKIVLDLAWGAAVNLAPLVFQTVGAEVICLHDRADGDRINVNCGSTHLESLQAAVINQQADLGFAFDGDADRVLAVDSQGRVVDGDYILYFWGRSLLEAGQLPDGLLVATVMANLGFERAWQKLGGQFLRTAVGDQHVQAQMWETGAMLGGEQSGHILCHHYGVSGDGMQTALHLAALVQKSAVSLANLVDHSFVTYPQILRNVRVEDREVRRNWQQCEPLRREIRKAETAMAEKGRILVRASGTEPLIRVMVEAETLELANFWTERLVAAVRSYLL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RLMN_YERPP
Sequence: MSEQLLTASTPIDAAPLSDNTVQTTAPATSKINLLDLNRQQMREFFAEMGEKPFRADQVMKWMYHYCYDDFEQMTDINKGLRAKLQRVAEIRAPEVAEEQRSVDGTIKWAIKVGDQQVETVYIPEADRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGSLKSTGTRPITNVVMMGMGEPLLNLNNVVPAMDIMMDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRDEIVPINRKYNIETFLAAVRRYLDKSKANGGRVTVEYVMLDHINDSTEQAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVIDRTKRTLKKKMAGEPIAIKTV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK8_CAEBR
Sequence: MIDENFKKKLAVSRERVEDLFYFENSKEIGRGTYGLVYKAVPKHSNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKTKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGGPDMRGRVKIADLGFSRIFANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDTDWPDMKKMPDHQRLLNDARNEGTPIQTFPNSLQRYFDKWKINSQSSPYRLLVKLLTVDPLKRVSCEEAMNDIYFRKMERPPRETDDVFNRYPIPYAKKEQQITIPIDQFQQQQQQQQQQQQQQQQQQQQQQQQQMQQPQIGPPQMMGQPQMGQPQMGQPQMGQPQMGQPQMGQPQMVPSQMGQPPMGGPHPGVVAPDGHAHQMMQQQHQSQHHMQYQQMHDSMQGGMDDGGPQAKMMRMGNVPVGRYGPMGPPYGPQDFHAPQGPPMMQMMPQPGPSGYYQQRPGQPPGPGPQGYMNPQMGMTMGMRPQGVPQQAYMPGRGMPPPQGPNPQQQQQWQQYHR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.  Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 8, Cell division protein kinase 8, Mediator complex subunit cdk-8, Mediator of RNA polymerase II transcription subunit cdk-8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_METJA
Sequence: MVQMSEGFRRKTRKKLSKHPRERGLYPITRALREFKEGEYVHIVIDPSVHKGMPHPRFHGRTGIVVGKQGRAFIVKVRDGGKYKQIIAYPQHLRPATA
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: AROC_BORPD
Sequence: MSGNTLGTLFCVTNFGESHGPAIGCVVDGCPPGLALDAADIQAELDRRRPGTSRHVTQRQEADQVEILSGVYQGVTTGTPIALLIRNTDARSKDYSNIADTFRPGHADFTYTRKYGLRDPRGGGRSSARLTAPTVAAGAIAKKWLAEHHGVRVRGYMSQLGPIAIPFVSWDDVPANPFYAPNAAIVPELEAYMDQLRRDGDSVGARIEVVAENLPAGWGEPLYDRLDADIAHVMMGLNAVKGVSIGAGFGCIAQRGSEHGDEITPDGFVGNNAGGVLGGISTGQPVTVSLAIKPTSSIRVERRSVNSAGEPVMVQTLGRHDPCVGIRATPIAEAMLALVLIDHALRHRAQCG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NEP1_CANGA
Sequence: MVEDSKARIGGPNNSSVTKKQEPRLYVVLCEASLETYTSNDHRTSLLNCDDHQGILRKMGRDIAEARPDITHQCLLTLLDSPINKAGLLQVYILTKKNVLIEVNPSVRIPRTFKRFSGLMVQLLHKLSIRSMESSNTHLLRVVKNPVTKYLPADCRKVTLSFDAEVMRPQEYLGDKQSVCVFVGAMARGHDSFADEYVDDKIAISNYPLSASVACSKFCHGAEDAWAII
What is the function of this protein?
S-adenosyl-L-methionine-dependent pseudouridine N(1)-methyltransferase that methylates the pseudouridine corresponding to position 1189 (Psi1189) in S. cerevisiae 18S rRNA.  Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.  Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase NEP1, 18S rRNA (pseudouridine-N1)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL16_NAUPA
Sequence: MLMPKRTKYRKQQKGRNRGKAYRGSTLAFGTYGLKAVELGRINSRQIEAGRVALSRTMKRTGKIWIRVFPDKPLTAKPVGVRMGKGKGSVEEWVMNIKPGRIIFEITGVNNETAVRALTLAAAKLPFKTKIVSMESENELY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.