PharMolix/UniProtQA huggingface dataset:
Protein: GATA_NEIM0
Sequence: MTQYTLKQASVLLQSKQISAVELASAYLAAIAEKNPALNGYITIDQDKTLAEARAADERIAQGNASALTGIPVAYKDIFCQTGWRSACASKMLDNFISSYTATVVQNLLDEGMVTLGRTNMDEFAMGSTNENSFYGATKNPWNPEHVPGGSSGGSAAVVAARLAPAALGSDTGGSIRQPASHCGITGIKPTYGTVSRFGMVAYASSFDQAGPMAQTAEDCAILLNAMAGFDPKDSTSLEREKEDYTRDLNQPLKGLKIGLPKEYFGEGNSADVLTALQNTIDLLKAQGAELIEVSLPQTKLSIPAYYVLASAEASTNLSRYDGVRYGHRAAQFGDLEEMYGKTRAEGFGSEVKRRIMIGTYVLSHGYYDAYYLKAQKLRRLVADDFQTVFARCDLILAPTAPTAAPKIGADSSPVETYLSDIYTIAVNLAGLPALTLPAGFSGGGLPVGVQLIGNYFAEARILGAAHQIQLNSDWHGKRPE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: OCR_BPT7
Sequence: MAMSNMTYNNVFDHAYEMLKENIRYDDIRDTDDLHDAIHMAADNAVPHYYADIFSVMASEGIDLEFEDSGLMPDTKDVIRILQARIYEQLTIDLWEDAEDLLNEYLEEVEEYEEDEE
What is the function of this protein?
Prevents both degradation and modification of T7 DNA by the host restriction-modification complex (PubMed:32039758, PubMed:1095770).  Structural mimic of the phosphate backbone of B-form DNA that binds to and completely occupies the DNA-binding sites of all known families of the complex type I DNA restriction enzymes (PubMed:12235377, PubMed:32483229).  Thereby, inhibits the restriction endonuclease activity and protects the phage genome as it penetrates into host cytoplasm (PubMed:12235377, PubMed:32483229).  Inhibits host transcription by binding to the bacterial RNAP and competing with sigma factors (PubMed:32039758).  Inhibits the host exclusion defense system BREX (PubMed:32338761).
What are the official names of this protein?
Protein Ocr, Gene product 0.3, Gp0.3, Overcome classical restriction, Ocr.
Protein: Y9628_DICDI
Sequence: MEDPLSSYKLIKDLRSGGEGKAILYEKDGVKYVGKKRLFDNLKDANQGLKEAMSLARIVHPNTVRFEDAIMTQIGDQIEITIMMEFCEMGDLLDFLIELSEPQHHHTVTLGSELSSLNLGSEYTGSDIDSTTSRTSSSSSTNFEAALLLENNNNNTIQHSHSSSSLVNGTTSPTNATTPPITTTTPNNRHSISTPTLAGTTTATTASPSSPSSPSSPSSPSSPSSPLSPQQHPVTSPQRKSSKSERKKKCSLKERKCIVKMTVDLTKKIFKKDNSNHTTAATTTTTTNTTHSSSSSSNLNIEEHVIHSNEIKKGVDSIYLIEQTQLIEWLLDLSYGVQALHRASMIHRDLKSENIFISGSNKLKIGDFGLAIQSAHHTGSIHSETVGTYCYSSPEILNSTYDKTTDIFSLGCIFYELITLKLLSHNRIYLGEDMLNDRFDSMQFLSTFPEKYEKLAPLVLSMISKNPTFRPSIESIIETLQKMDTSLLKERVVIKRENTIKGIRKQLDKSHFQEASLLLATSFVKDPRFFNIFPPSDPHSIPHLQHLYKYILKVLSSYNCSIWGYFAIDGTMVSCFVWLNPEKKKEIRLSDCIKGSLSLVTKIGLKRVGLILDLMRFDDNILSMAQNNNNNPNTSTSNLQTFKGSSSSSSSSCNHWFLAYCCTSEIFRGNGIGSHMIENVLNWADHNGVETRTVVFENNSIEFFQHHGFEVGSEFKSNLPKGVNKVMVLVRKPKQIY
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0269628.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: OTXH_CAEEL
Sequence: MSLTSSSAPSDSIVELIQSQNLSGSGSGTGGNTGSTTMNSGNFIPTPSLTGTGASQSSGSASSGNFVSPDETDTKPSPSLMDHNDPTSSLSQQLAQGATLTSPYSTTTVDPSSLYFQLSPMSYIPNVSSATTVAAANMSAYFNQKSAYPTSHLGFPSNVGSHSFLQSNMYIPSSLSDCPTATMGSMSWNANQPGFSRKQRRERTTFTRNQLEILESYFVKTRYPDIFMREDMAHKIQLPESRVQVWFKNRRAKARQQKKTLAPSNSGVTCSGNNGSTGGGSSNGSTGSEVQPSSPATTDSELKFSEVIKEECDEQSISPSADDQKGVNSYINPISSSSGTTSYNGTSSFRPQAQYPYASYPAYDFQYSQSNTNSTNTYTLDGNSTWKFQMS
What is the function of this protein?
Probable transcription factor (PubMed:21350017, PubMed:25614239).  Binds to a motif including the sequence 5'-TAA[TG]-3' in regulatory promoter elements (PubMed:21350017, PubMed:25614239).  Modulates expression of its own, and of various other, genes in the AFD thermosensory neurons or AMsh amphid sheath glia, incuding the nuclear hormone receptor nhr-38, the LIM homeobox ceh-14, cyclic nucleotide-gated channel tax-2, receptor-type guanylyl cyclase gcy-8 and VEGF-related protein ver-1 (PubMed:11580895, PubMed:21350017, PubMed:25614239).  Required for the development and cell fate of AFD neurons (PubMed:11580895, PubMed:21350017, PubMed:22298710).  In concert with ceh-14, perhaps as components in a complex, specifies identity of AFD neurons, acting by synergistically regulating gcy-8, gcy-18 and other genes (PubMed:25614239).  Involved in thermosensory behavior, thereby regulating entry and exit into the dauer larval stage of development (PubMed:11580895).  Required in amphid sheath AMsh glia remodeling during entry into dauer stage, acting by positively regulating the expression of ver-1 in AMsh of amphid sensory neurons (PubMed:21350017, PubMed:22298710).  May be essential for early development (PubMed:22298710).
What are the official names of this protein?
Homeobox protein ttx-1, Abnormal thermotaxis protein 1, OTX homeobox homolog ttx-1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
Protein: TR03_CURCL
Sequence: MALQERRAAVTSSDILSAHAISSPALAAAAINFAASFHRDARTCCSAHERSQLQKVYRDKILANDKFTANIAAAFLSVLGPNAGRNDAGAERERWGDFDRLAQRGKNMRDRESQHLQHQSGIIAAWGPRCFEYYGWHVLPLPLLRQVHDLAVLIPSWDDAVELLNSRMLLRHELRVLHGNNKALRIGEHSAASKVQDSRSPVERTDIVAALDWARANATSAAARQAVKEAAQGMNGTPINTFGLKRDCYGMVVPSVGPYDPDGDDDNDEDVVDVSPRPAKHIKLSAAEPLRLMFPGSLSHVQACQRHDTDGEKASTAPIRSNKLSQSKQPELDTAAESLRTRHIHNERINEPLDEVSDCSLSLQTIAVGGGSAQEETPDQDVEHAHPEVEITSAISSELRKVDERTDGIRIGRVIMRRSHCMVREQDNQTNEEGTGEVQSQRDRRARDLGKDMETDMDIDSQLEEMLDIHALEAQRNHEEMSDGEDVVAGVAGPGTPTHRAAEEGGCREKEAENAKTDEEQVQDKAALDQAGNTNTNREVENAAPKAHSQEGALRASRTGTIVERTVELHSTHSIHQRASVNTTAPTVARSSDSDDSDSLHSPTALQNLQAYIDTRTHQLTQVLSQLNSTPDVRHHAQLQLDWLSPQRWASVYVEPEHHMGATSSASSDSADIWCLDWDTFHQYADSNHVFRRPVVIKQKFQDSGMYEVDRYVDMLWQRFPEQHIEVQNSITGTSRLMSMAEYCSTALTVTEAGTSLSDNTTSVSNAVNLRCLARADEPLLTRLERFQLLSTLASRVAGTIGRTEHSPPSNLESLLGFDALSFADAFSSSHANLFGGSWVRCLDGLKIYAIAADLDAEDWRRFADEGYKWSPRGKGRLIALEEDDVLFIPPGLRAIHASFTPEPCLMEGGMLWDECAIPEILDELLWIARHQAGTVQPLEFQLSSLIDALEQWLNENNHINQSSPSHTAAEERQTLKASIQSLRDCLSGRSAAFPS
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of KK-1, a novel cyclic decapeptide compound with potent antifungal activity (PubMed:29686660).  The nonribosomal peptide synthetase (NRPS) catalyzes the elongation and cyclization of the decapeptide chain composed of 1 pipecolic acid residue (Pip), 1 alanine residue (Ala), 1 aspartic acid residue (Asp), 1 isoleucine residue (Ile), 1 glycine residue (Gly), 1 tyrosine residue (Tyr) and 4 valine residues (Val) (PubMed:29686660).  The Asp, Ile and 3 Val residues are N-methylated by the 5 methyltransferase domains from the NRPS (found in modules 3, 5, 6, 7 and 9), whereas the Tyr residue is O-methylated, probably by the cluster encoded O-methyltransferase OMT (PubMed:29686660).  The other tailoring enzymes from the cluster may be involved in further modifications leading to the synthesis of KK-1 (Probable).
What are the official names of this protein?
KK-1 biosynthesis cluster protein TR03.
Protein: IRRE_DEIDV
Sequence: MTDPAPPPTALAAAKARMRELAASYGAGLPGRDTHSLMHGLDGITLTFMPMGQRDGAYDPEHHVILINSQVRPERQRFTLAHEISHALLLGDDDLLSDLHDEYEGDRLEQVIETLCNVGAAALLMPAELIDDLLTRFGPTGRALAELARRADVSATSALYALAERTAPPVIYAVCALSRQEDEGEGGGAKELTVRASSASAGVKYSLSAGTPVPDDHPAALALDTRLPLAQDSYVPFRSGRRMPAYVDAFPERQRVLVSFALPAGRSEPDADKPEAPGDQS
What is the function of this protein?
Plays a central regulatory role in DNA repair and protection pathways in response to radiation stress.  Acts as a site-specific metalloprotease that cleaves and inactivates the repressor proteins DdrOC and DdrOP3, resulting in induced expression of genes required for DNA repair and cell survival after exposure to radiation.
What are the official names of this protein?
Radiation response metalloprotease IrrE, DNA repair regulatory protein IrrE.
Protein: PFKA_STAEQ
Sequence: MKKIAVLTSGGDSPGMNAAVRAVTRTAIYNNIEVYGVYQGYQGLLDDDIHKLELGSVGDTIQRGGTFLFSARCPQFKEEDVRKKAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIESVDKIRDTASSHARTFIVEVMGRDCGDLALWAGLSVGAETIVLPEVNTDIKDVAEKIEQGIKRGKKHSIVMVAEGCMSGQECADELTKYINIDTRVSVLGHIQRGGSPSGADRVLASRLGGYAVELLKQGETAKGVGIRNNQLTSTPFDEIFAESNRKFNSQMYELAKELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7A_META3
Sequence: MAVYVKFDVPQEMEEKTAEVLSKSEKVKKGANEVTKAVERGTAKLVVLAKDVQPEEIVAHIPIICEEKGIPYTYIATKEDLGKAIGLEVSTAAVAIIAEKDANALKDLVEKINGLKA
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6E_SULAC
Sequence: MPDFKIVVSDPKTKEDKKEKLKVKVSDKVKSNQGEKEGKAIPLARINDKIKQALNLDDFLTLEITKQEGDKKVKIKGHFKIEVDNTVPDGEVWISKSMAEKFGAEEFEALAYRTRAFQLSLDQSKLPNLVGTKIGDVIDINVSGVNLKLKITGGSDNSGFSMRFDVGGGAKRKILVSGPPGYYPKEDGLRRKRTVRGNMITPEIVQINTIMIR
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: FRS12_ARATH
Sequence: MESVDTELTSFNNMVAKSSYPVRILHHNNGISEDEEGGSGVEPYVGLEFDTAEEAREFYNAYAARTGFKVRTGQLYRSRTDGTVSSRRFVCSKEGFQLNSRTGCTAFIRVQRRDTGKWVLDQIQKEHNHELGGEGSVEETTPRPSRAPAPTKLGVTVNPHRPKMKVVDESDRETRSCPGGFKRFKGGGGEGEVSDDHHQTQQAKAVTGTEPYAGLEFGSANEACQFYQAYAEVVGFRVRIGQLFRSKVDGSITSRRFVCSREGFQHPSRMGCGAYMRIKRQDSGGWIVDRLNKDHNHDLEPGKKNDAGMKKIPDDGTGGLDSVDLIELNDFGNNHIKKTRENRIGKEWYPLLLDYFQSRQTEDMGFFYAVELDVNNGSCMSIFWADSRARFACSQFGDSVVFDTSYRKGSYSVPFATIIGFNHHRQPVLLGCAMVADESKEAFLWLFQTWLRAMSGRRPRSIVADQDLPIQQALVQVFPGAHHRYSAWQIREKERENLIPFPSEFKYEYEKCIYQTQTIVEFDSVWSALINKYGLRDDVWLREIYEQRENWVPAYLRASFFAGIPINGTIEPFFGASLDALTPLREFISRYEQALEQRREEERKEDFNSYNLQPFLQTKEPVEEQCRRLYTLTVFRIFQNELVQSYNYLCLKTYEEGAISRFLVRKCGNESEKHAVTFSASNLNSSCSCQMFEHEGLLCRHILKVFNLLDIRELPSRYILHRWTKNAEFGFVRDMESGVSAQDLKALMVWSLREAASKYIEFGTSSLEKYKLAYEIMREGGKKLCWQR
What is the function of this protein?
Putative transcription activator involved in regulating light control of development.
What are the official names of this protein?
Protein FAR1-RELATED SEQUENCE 12.
What is the protein family that this protein belongs to?
Belongs to the FHY3/FAR1 family.
What are the subcellular locations of this protein?
Nucleus. Note=The nuclear localization is independent of the light treatment.
Protein: DIAP3_MOUSE
Sequence: MERHRARALGRDSKSSRRKGLQSAPPAGPYEPGEKRPKLHLNIRTLTDDMLDKFASIRIPGSKKERPPLPHLKTVSGISDSSSLSSETMENNPKALPESEVLKLFEKMMEDMNLNEDKKAPLREKDFGIKKEMVMQYINTASKTGSLRSSRQISPQEFLHELKMGYTDERLFTYLESLRVSLTSHPVSWVQSFGHEGLGLLLDILEKLINGQIQEKVVKKTQHKVIQCLRALMNTQYGLERIMSDKRSLSLLAKAMDPRQPAMMADVVKLLSAVCIVGEESILEEVLEALTSAGEERKIDRFFSIVEGLRHNSVNLQVACMQLINALVTSPDDLDFRLHLRNEFMRCGLKEILPNLKGIKNDGLDIQLKVFDEHKEEDLSEFFHRLEDIRAELDEASDVYSMLWDTVKETRAEGHFLSILQHLLLIRNDRFIREQYFKLIDECVSQIVLHRDGTDPDFTYRKRLDLDLSQFVDVCIDQAKLDEWEEKASEHCKKFEKECTDHQETQAQLQKREAKINELQAELQAFKSQFGALPPGTKIPLQPSVEGEAGPSALPPAPPALSGGVPPPPPPPPPPPPPLPGMPMPFGGPVPPPPPLGFLGGQSSIPLNLPFGLKPKKEFKPEISMRRLNWLKIGPNEMSENCFWIKVNENKYENRDLLCKLENTFCCQEKEKRNTNDFDEKKVIKKRMKELKFLDPKIAQNLSIFLSSFRVPYEKIRTMILEVDETQLSESMIQNLIKHLPDEEQLKSLSQFRSDYNSLCEPEQFAVVMSNVKRLRPRLSAILFKLQFEEQVNNIKPDIMAVSTACEEIKKSKGFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLHFLVDVCEEKHADILHFVDDLAHLDKASRVSVEMLEKNVKQMGRQLQQLEKNLETFPPPEDLHDKFVIKMSSFVISANEQYEKLSTLLGSMTQLYQSIMGYYAVDMKKVSVEEFFNDLNNFRTSFMLALKENIKKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDETGVMDSLLEALQSGAAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLTEGSRPHHSINCNSTRTPVAKELNYNLDTHASTGRIKAVEKEACNAESNKKKEMELLGSVAKSESVPEVEALLARLRAL
What is the function of this protein?
Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers (PubMed:10678165, PubMed:23558171).  Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor (PubMed:10678165, PubMed:23558171).  Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization (PubMed:10678165).  DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (PubMed:10678165).  Also acts as an actin nucleation and elongation factor in the nucleus by promoting nuclear actin polymerization inside the nucleus to drive serum-dependent SRF-MRTFA activity (PubMed:23558171).
What are the official names of this protein?
Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, p134mDIA2, mDIA2.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=During mitosis, co-localizes with the actin-rich cleavage furrow and with the microtubule-rich central spindle during cytokinesis (By similarity). Shuttles between the cytoplasm and the nucleus (PubMed:19117945).
Protein: GLYA_HELPY
Sequence: MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFASVMEAMGSVLTNKYAEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQFANVQAHSGSQANNAVYHALLKPYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVNLDGYIDYEEALKIAQSVKPEIIVCGFSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTGEHAHPFPHCHVVSSTTHKTLRGPRGGIILTNDEEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFKAYAQLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLHVKEELKAMVNQFPVYHQPIF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLAE_PENCR
Sequence: MNTTRTLDNSTIHLPRILCLHGGGTNARIFRAQCRGLIAGLKSEYRLVFAQAPFASQAGSDVLSVYSQWGPFRRWLRWRPEHPVIPPEDAVQEIDTWLEKAMHQDDLAGATGEWIALLGFSQGAKVSASLLYRQQSWQELFGTRPAGINFRFGILLAGQAPFISMDSDLTLDPPLPDASQITDLKHSERELFYGKGHVLRIPTLHVHGLRDKGLDHHRKLFEDFCAPQSRRLIEWDGDHRVPLKLKDVSLVIHQIRELAKETGVY
What is the function of this protein?
Esterase; part of the cla gene cluster that produces clavatol and ortho-quinone methide (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).  The non-reducing PKS claF is responsible for the formation of clavatol from successive condensations of 3 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit, and 2 methylation steps (PubMed:30811183).  The esterase claE probably collaborates with claF by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity).  The clavatol oxidase claD then converts clavatol to hydroxyclavatol (PubMed:30811183).  Spontaneous dehydration of hydroxyclavatol leads to the accumulation of the highly active ortho-quinone methide (PubMed:30811183, PubMed:31860310).  On the other hand, the PKS-NRPS hybrid traA is involved in the formation of crustosic acid, with the help of traB and traD (PubMed:30811183).  The polyketide synthase module (PKS) of traA is responsible for the synthesis of the polyketide backbone via the condensation of an acetyl-CoA starter unit with 3 malonyl-CoA units (PubMed:30811183).  The downstream nonribosomal peptide synthetase (NRPS) module then amidates the carboxyl end of the polyketide with L-malic acid (PubMed:30811183).  Because traA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase traG (By similarity).  Crustosic acid undergoes decarboxylation and isomerization to the terrestric acid, catalyzed by the 2-oxoglutarate-dependent dioxygenase traH (PubMed:30811183).  Both acids are further converted to the 2 gamma-butyrolactones (R)-5-methyltetronic acid and (S)-5-carboxylmethyltetronic acid, with involvement of the cytochrome P450 monooxygenase claJ (PubMed:30811183).  Spontaneous addition of the methide to these gamma-butyrolactones leads to peniphenone D and penilactone D, which undergo again stereospecific attacking by methide to give penilactones A and B (PubMed:30811183, PubMed:31860310).
What are the official names of this protein?
Esterase claE, Terrestric acid biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: TRMB_DICDI
Sequence: MVYQKQEPKKKKAIKPYHRIKAHANPASDYNFYYPTGPESYDWTKNYPQQAMNEKKVEIADVGCGYGGLLISLSSLFPERLSVGMELRDKVVQYVEERIDKLREKHVGQFQNISVIRTNAMKYLPNYFEKGQLQKIFFLFPDPHFKKATHKRRIISPTLLSEYAYILAPGAYAYFISDVEELYLWMFEHFKNHPLFEQVERDIAENDSCIPLIVNSTEEGRKVNRIDGKKWFAVFRRITDPSKKDLTFKNYTLTSPKEIDSTTTTTTSTATITEVESK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Methyltransferase-like protein 1 homolog, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDM34_CANGA
Sequence: MSFRFDRSVFESADFNERLRERLTGALNPKSRRHVERADEAGNEDDSSGHQRKSGGSLDILKNDIIVEKVDFSRIPNLEILDLDVGLGVSSISSGGGGSSMMKGICKISIEGAMLQVRTVIESNLLMLSMADSPEFVTPTLITNDSFSLPITMTFSNIKMEAISKVFFVARNSGIGISFDDVVLDFKFDCSIKILQTTIEKRLKRAMELLFKDTLPTALFNMSQSWFTNSDGSRSSAKHKKDTCDENNQPSAPKIIFEDADLQELSPANMLRLSTLVSSRQTLSLHSTVSSTLSLIPGCLERQNLYRFISRMPSLSNYYSSYVDHKKERAGTPSLLMNKRPSVDYLLRRSSSSGNSLMSSQAYFDKESNLLPMEVLEENAYDLDVITDIQNKLYMRSTDHDEQVNHTKPRRRKIKIGKNKKDKPAYKEEIEQQEPVQSTITVSMPFEEPQIIIEHNDETEAVKEERESVLSSPKLIRSTMDKTYTNSRILNTLLQKNGNLLDEETRLRAQSIDSVAHTKMGYLLGLNHIATPPPPPYY
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RL34_SYNJB
Sequence: MTQRTLRGTNRRRIRVSGFRARMRTATGRQVLRRRRAKGRYRLAVS
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARGJ_PARBP
Sequence: MKAHQSLHVVAGFVRFPMSKTGQSRCYSILKDISIPASKQKFVPSSGTYPKGFLAAGAHAGVKESNTQFPDVALICSETPCSAAAVFTTNKFQAAPVQVSKQVLEAREGADITGVVINSGCANAVTGKGGLEDAKSMSAKVDECNGTPSTSSKRPSTLVMSTGVIGQRLPIEKILNTIPVAHSSLSSTHKAWLTAARAICTTDTFPKLLSRTFTLPSSPNHTYRIAGMTKGAGMIHPNMATLLGILCTDVPISPAALKLLLSHAVSRSFNCISIDGDTSTNDTVALLANGAAGGQTITTPSSPNYAAMQTVLTSFAQSLAQLVVRDGEGATKFVTVRVLNSPSQADARAIASTIARSPLVKTALYGKDANWGRILCAIGYTQGIQAGTVVPERTSVSFKPVDGSEELKLLVNGEPEIVDEERAARILQDEDLEIVVDLGGGERGEEGMGGEEGIYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GPMA_BURA4
Sequence: MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGRNEAYQAGELLREAGYTFDIAYTSVLKRAIRTLWHVQDRMDLMYLPVVHSWRLNERHYGALSGLNKAETAAKFGDDQVLVWRRSYDTPPPALEPTDERAPFNDPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVRSGKQVLIAAHGNSLRALIKYLDGISDSDIVGLNIPNGVPLVYELDEDLKPLKHYYLGDQDAIAKAQAAVAKQGKAG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: STOM_HUMAN
Sequence: MAEKRHTRDSEAQRLPDSFKDSPSKGLGPCGWILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPIDMLQGIIGAKHSHLG
What is the function of this protein?
Regulates ion channel activity and transmembrane ion transport.  Regulates ASIC2 and ASIC3 channel activity.
What are the official names of this protein?
Stomatin, Erythrocyte band 7 integral membrane protein, Erythrocyte membrane protein band 7.2, Protein 7.2b.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545).
Protein: NUOA_ENT38
Sequence: MSMSTSTEVVAHHWAFAIFLIVAIGLCCLMLIGGWFLGGRARARHKNTPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFILVLLAGLVYLVRIGALDWTPTRSRRELVNPENSNSNRQQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.