PharMolix/UniProtQA huggingface dataset:
Protein: ACEK_PECCP
Sequence: MTRDLEKLVAQTILQGFDAQYGRFLEVTAGAQQRFEQADWPAVQQAMKQRIHLYDHHVGLVVEQLRCITGIRCDDADFLARVKHIYTRLLPDYPRFEIAESFFNSVYCRLFNHRELTPDKLFVFSSQPEQRFREIPRPIAKTFVPTDGWQNMLEKLLSDVPLRLPWEDLPRDIGYIVAYLQRTFSAEQLAQATLQMANELFYRNKAAWLVGKLSLPDGIFPFLLPIHHNERGALFIDTCLTSQADASIVFGFARSYFMVYAPLPSALVAWLRDILPGKTTAELYLAIGCQKHSKTEYYREYLHYIAESEEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDRFAPQKEVSAERVMACYQLVKEHDRVGRMADTQEYENFVIDKHRISSELLDELWREVPDKLEDLGDRLVIRHLYMERRMTPLNLYLEQANAQQLHDVIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRKIPPPRHPEDELAAEPWYSVAPNDVFPEEFPHFLCSDRHIRTLFEEMHGDLFCADYWRALQQRIREGHIEDVYAYRRRKRFSQRADPRYTTAENDSGFCRNPA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGH_LACPL
Sequence: MENQYKVELHNVTKEYDLYRSNNDKLKHFFNIGNVDVPRFWSLKGVSLNVKPGEALGIIGINGSGKSTISNIISGIIPQTTGTVDVHGDTSIISIGAGLKWNLTGDENIRLKGLMQGLSIKEIQAVRDDIVDFADIGDFIGQPVKDYSTGMRSRLGFAIAVHINPDIMIIDEALSVGDDTFYQKCVDKIMEFKKQGKTIIFVSHNLRQVELLCDRVAWMHFGDLLEVGETKETVDHYRKFSKDFKAQTAAYRKKYQVGKKKEQADFDIVAYERQLVEEKAKDSDKSKQAVSRQVHRTLYKQILPEKMTIATKLVMLVAIVLFVFFALVNVSGHSVTSAIENPTVLLHPVNHYIKSQSVLFNSK
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ERF3_DEBHA
Sequence: MSDDQQYNQDKLSQDFQNTSIGSGEQQQQSYQQYQQQPQQNNFNANSAPTFTPSGQQGGYQGGYQGGYQGGYQNYSQGGYQNYNQGYQNYNQGYQGYQNNNRGGYNNYNNRGGYNNYNNYNQQDQQPVQNQGMSLADFQKQQNAQANLNKPKKTLKLASSSGIKLANAKKAPETESKEATPAATEKEATPAATEKEATPAATEKEATPAATEKETTPAPAKKEATPASVKSESKPASKSTSKVATKESTPVTSDKVIQEQVDEVDEEVVKDMFGGKDHVSIIFMGHVDAGKSTMGGNILYLTGSVDKRTVDKYEREAKDAGRQGWYLSWVMDTNKEERSDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGILVISARKGEYETGFEKGGQTREHALLAKTQGVNKIIVVVNKMDDPTVGWAEDRYKDCITKLGTFLKGIGYAKDDIIFMPVSGYTGAGIKDRVNPKDCPWYSGPSLLEFLDNMKTMQRHINGPFMLPISGKMKDMGTIIEGKIESGHIKKGGNLLLMPNKASIEVVAIFNETEQECDAAFCGEQVRLKIKGVEEEDLAPGYVLTSPLKPIKTITRFEAQIAIVELKSILSNGFSCVMHLHTAIEEVTFIELKHKLEKGTNRKSKKPPAFAKKGMKVIAILETNESVCAETYADYPQLGRFTLRDQGTTIAIGKITKVL
What is the function of this protein?
Involved in translation termination.  Stimulates the activity of ERF1.  Binds guanine nucleotides.
What are the official names of this protein?
Eukaryotic peptide chain release factor GTP-binding subunit, ERF-3, ERF3, ERF2, Polypeptide release factor 3, Translation release factor 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPM_SALEP
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: GALT_PEDPA
Sequence: MSSLEQFVQVVIDSPSPYTNLDRIYVHNRILGLVGEDQPVEATDEQVTSLVDALVKTAVQNGKIEDAQSDRSILADQLMDLVTPLPSILNQRFWDKYQVSPKAATDYFFNLSKTNDYIKTRAIAKNVSFPAETDFGELEITINLSKPEKDPKAIAAARNQPQDGYPLCQLCMQNEGYLGRLGYPSRSNHRIIRMTLGGETWGFQYSPYAYFNEHSIFLDQIHRPMVINRQTFTNLLEIVKQLPHYFVGSNADLPIVGGSMLSHEHYQGGRHVFPMMKAPIARTIDLGVAGVEAGIVKWPMSTIRLVGSDVVALTDAAVKIHDAWMNYSDESVDVRAFTDGTRHHTTTPIAYKDGENYVLDVVLRDNQTSAEFPDGIFHPHQDVQHIKKENIGLIEVMGRAILPARLKTELVEVEKYLLGQTNQMAEMHQAWADQLKATNSITAENVTAVVNAAVGNVFARVLADAGVFKWDDAGEAAFARFISAIN
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_SULIN
Sequence: MSSEKEYVEMLDRLYSKLPEKGRKEGTQALPNLIIFNIGNTTMIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGELIIQGKFSSQVINTLMERFLKAYVECSTCKSLDTVLKKEKKSWYIVCLACGAQTPVKPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: HEXD_HUMAN
Sequence: MSGSTPFQMRLVHLDLKGAPPKVSYLSEIFPLFRALGANGLLIEYEDMFPYEGPLRLLRAKYAYSPSEIKEILHLAGLNELEVIPLVQTFGHMEFVLKHTAFAHLREVGSFPCTLNPHEAESLALVGAMIDQVLELHPGAQRLHIGCDEVYYLGEGEASRRWLQQEQNSTGKLCLSHMRAVASGVKARRPSVTPLVWDDMLRDLPEDQLAASGVPQLVEPVLWDYTADLDVHGKVLLMQKYRRCGFPQLWAASAFKGATGPSQAVPPVEHHLRNHVQWLQVAGSGPTDSLQGIILTGWQRYDHYSVLCELLPAGVPSLAACLQLLLRGGFDEDVKAKVENLLGISSLEKTDPVREGAGSFPGSNILALVTQVSLHLRSSVDALLEGNRYVTGWFSPYHRQRKLIHPVMVQHIQPAALSLLAQWSTLVQELEAALQLAFYPDAVEEWLEENVHPSLQRLQALLQDLSEVSAPPLPPTSPGRDVAQDP
What is the function of this protein?
Has hexosaminidase activity.  Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates.  Has a preference for galactosaminide over glucosaminide substrates (PubMed:27149221).
What are the official names of this protein?
Hexosaminidase D, Beta-N-acetylhexosaminidase, Beta-hexosaminidase D, Hexosaminidase domain-containing protein, N-acetyl-beta-galactosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
Protein: HSLV_BORBR
Sequence: MEQFHATTIVCVRRGNHVALGGDGQVTLGNIVIKGTARKIRRLYHDKVLAGFAGATADAFTLQERFEAKLEKHQGHLMRAAVELTRDWRTDRVLRRLEAMLIVADTEHTLVLTGNGDVLEPEHGLAAIGSGGAYAQSAALALLRNTELPPEAIVKQSLEIAGDLCIYTNQNHVIETLGA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_ECO81
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: VE6_HPV17
Sequence: MDRPKPQTVRELADTLCIPLVDILLPCRFCNRFLAYIELVAFDLKGLQLIWTEEDFVFACCSSCAYATAQYEFSKFYEQSVSGRELEEIEHKPIGEIPIRCKFCLKKLDLLEKLDTCYRHQQFHKVRRNWKGLCRHCGSIG
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: Y153_PSEP1
Sequence: MLSWAITFLIIAIVAAVLGFGGIAGAATGIAKILFIVFLVLFVASFFFGRGRG
What are the official names of this protein?
UPF0391 membrane protein Pput_0153.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLM_SHEEP
Sequence: MASLSHILVLCVGLLAMVNAEAPQEHDPFTYDYQSLRIGGLIIAGILFILGILIVLSRRCRCKFNQQQRTGEPDEEEGTFRSSIRRLSTRRR
What is the function of this protein?
Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell.  Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated.  Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1.  Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone.
What are the official names of this protein?
Phospholemman, FXYD domain-containing ion transport regulator 1, Sodium/potassium-transporting ATPase subunit FXYD1.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Membrane, caveola. Cell membrane, sarcolemma, T-tubule. Note=Detected in the apical cell membrane in brain. In myocytes, localizes to sarcolemma, t-tubules and intercalated disks.
Protein: ERG_CHICK
Sequence: MASTIKEALSVVSEDQSLFECAYGSPHLAKTEMTASSSSEYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPNQVNGSRNSPDDCSVAKGGKMVSSSDNVGMNYGSYMEEKHIPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVDILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGATFIFPNTSVYPEATQRITTRPDLPYEQARRSAWTSHSHPTQSKATQPSSSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSMYKYPSDLPYMSSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPAAHMPSHLGTYY
What is the function of this protein?
Acts as a transcriptional activator.
What are the official names of this protein?
Transcriptional regulator Erg.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_SALG2
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLAREALGTNWLKLEIHPDARWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETKTMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVMMATAFRLAVEAGLLARQAVPGNRSTYASATSPLTGFLEALA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_LACDE
Sequence: MTVKIGINGFGRIGRLAFRRIMDLGEETKDIEVVAINDLTTPAMLAHLLKYDSTHGTFDHEVSATEDSLVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGNDLKTIVYSVNQDTLTADDTIVSAGSCTTNSLAPMANALNKEFGIQVGTMTTIHAYTATQKVLDGPDRGNNFRNARAAAENIIPHSTGAAKAIGLVLPELNGKLDGHAQRVPVKDGSETELVTILDKKVTAEEVNAAMKKYESPSFAYNADQIVSTDVLGMTAGSIFDPTQTQVITAGDKQLVKTVAWYDNEYSFTCQMVRTLLHFATL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFA4_NEUCR
Sequence: MTNLQTGPTTRGLQRFAIPAVCGLIIFLGYYSQYLFNTSADLAPGPLTCRESLIFNILLVCLWLTYYQACTVDPGQYKFPPKEKEDGDNNNKRGGRGPQKAKWCKKCDAPKPPRAHHCRHCARCIPRMDHHCPWTGNCVSLQTFPHFLRFLVYTNAALVYFARLLWTRLYYGLWDQRHVPAYLGPSVGALLGCTMLSIAWFATQFALMVLLVTTVRSWMLGKTMIEEWEAERHETLLARSYDGDDYWGADGHGGFVPVKVEFPYDNGFWSNMAQAMGTNNFLRWFLPVGGGGPKISNDTPWKGTGWEYEENGFNDRVGMWPPPDPEKLRRERAGAGGKWPGARENLNTEKPEVDYYRSSEDMKTAFKRRQQEDLRRRQQRRQHSSEEDEIMAELEEDEGYEQRSRTRSPPQDGRAWMNSEGDTLWDYGVDVDEEENYGYPGQGVSESLPLVKTATGYNDGQGDEDEDVPLAELIRRRKVKSNGVHE
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase pfa4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL17_SULNB
Sequence: MRHKHGYRKLNRTSAHRAALLKNLSIALTKEGKIETTLPKAKELRSYYEKLITKAASGDFNAHRAIFAMLQHKESTNTIVNEIAPKYADRNGGYTRIIKTRMRKGDSAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ESXC_STAAM
Sequence: MNFNDIETMVKSKFKDIKKHAEEIAHEIEVRSGYLRKAEQYKRLEFNLSIALDDVESTAKDVQTAKSSANKDSVSVKGKAPNTLYIEKRNLMKQKLEMLGEDIDKNKESLQKAKGIAGEKASEYFNKAMN
What is the function of this protein?
Implements its pathogenic function during infection.
What are the official names of this protein?
Type VII secretion system extracellular protein C, Ess extracellular protein C.
What is the protein family that this protein belongs to?
Belongs to the EsxC family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: LFTR_SHIB3
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL905_MIMIV
Sequence: MSKKFKMKRAKNLNGFSIIHDYVTPDQEKKLLKKINESEWVVDYQRRLQYYNYRNELFEPYDLIPIPNKIPKYLDQLINQMILDKIIDQKPDQIIVNEYKPGEGLKPHFDRKDYYQNVIIGLSLGSGTIMEFYKNKPIPEKKKIYIPPRSLYIIKDDARYIWKHGIPPRKYDEINGKKIPRETRISITFRNVIKEKVKHDNIVYPKRSPN
What are the official names of this protein?
Uncharacterized protein L905.
Protein: TRMD_NEIMA
Sequence: MLIQAVTIFPEMFDSITRYGVTGRANRQGIWQFEAVNPRKFADNRLGYIDDRPFGGGPGMIMMAPPLHAAIEHAKAQSSQAAKVIYLSPQGKPLTHPKAAELAELPHLILLCGRYEGIDERLLQTSVDEEISIGDFVVSGGELPAMMLMDAVLRLVPGVLGDMQSAEQDSFSSGILDCPHYTKPLEFQGMAVPEVLRSGNHGLIAEWRLEQSLRRTLERRPDLLEKRVLIPKESRLLETIRQEQREIQS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRP2_ORYSJ
Sequence: MTAPADKGKKAKTDADGGAAEENEQIDGALVLSIEKLQEIQDELEKVNEEASDKVLEVEQKYSEIRRPVYLRRSDVIQTIPDFWLTAFLSHPLLSELLTEEDQKMFKYLESVDVDDSKDVKSGYSITLTFSENPYFEDKELTKTYAFADDGTTTINATSIKWKEGMEIANGNAKKKGSKRPLVEESFFTWFTDTEHKSLADGVQDEVAEIIKEDLWPNPLKYFNNEAEELGEDDDEEGSDADEGEEDEEEEN
What is the function of this protein?
Acts as histone H2A/H2B chaperone in nucleosome assembly.
What are the official names of this protein?
NAP1-related protein 2, Protein SET homolog 2.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GCH1_STRZP
Sequence: MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGLGQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKLARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATLTTVARGLFETDKDLRDQAYRLMGL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ILVD_DEHMB
Sequence: MKSEDVKLGIERAPHRSLLRALGLNTESFQKPFIGIVNSFTEVVPGHIHLRQISEAVKEGINAAGGVGFEFNTIAVCDGIAMNHAGMKYSLPSREIIANTVEIMAMAHAFDGLVFIPNCDKVVPGMLMAACRLNIPSIFVSGGPMLAGRLRKNDQVSCVDLNSVFEAVGQVAKGQMTEEELLELEKVACPGCGSCAGMFTANTMNCLTEALGMALPGNGTIPAVDSRRTQLAKSAGQQIMQLIKDNICPKDIITPDAIHNAFSLDVALGGSTNSVLHVMAVAHEAGADFSLEQINRISDCTPNLCKLRPSGPYHIENLDQSGGIGSVLKELKPWLKNDARTVSGKTIGQLADAAPKADNKVIRFASNPYSPKGGLAVLFGNLAPNGSVVKRSAVAPEMMVHRGPARIFDSEELATKAIMGGKIKTGDVLVIRYEGPKGGPGMREMLTPTSLLAGMGLDKEVALITDGRFSGATRGAAMGHVSPEAAACGPIAALQDGDMINIDIHNYKLSVELSDEEIQKRLANVPVFEPKIKSGYLKFYTENVTSASTGAVFKD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y1552_YERPY
Sequence: MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLSEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YPK_1552.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZHX1R_HUMAN
Sequence: MLRKLWQWFYEETESSDDVEVLTLKKFKGDLAYRRQEYQKALQEYSSISEKLSSTNFAMKRDVQEGQARCLAHLGRHMEALEIAANLENKATNTDHLTTVLYLQLAICSSLQNLEKTIFCLQKLISLHPFNPWNWGKLAEAYLNLGPALSAALASSQKQHSFTSSDKTIKSFFPHSGKDCLLCFPETLPESSLFSVEANSSNSQKNEKALTNIQNCMAEKRETVLIETQLKACASFIRTRLLLQFTQPQQTSFALERNLRTQQEIEDKMKGFSFKEDTLLLIAEVSVSLGFM
What are the official names of this protein?
Zinc fingers and homeoboxes protein 1, isoform 2, ZHX1-C8orf76 readthrough transcript protein.
Protein: Y1415_HAEIN
Sequence: MTMMISEVTFNKIFPHAVKGVYQAISAQIEKAGCVNKMQQAMFLAQCGHESGGFIRFKENLNYSWLGLSQTFRKYFPDPLTAKKYERKPELIANRIYANRLGNGDEKSGDGWKYRGRGLIQITGKDNYAAFRKWLGRDIEPEDVAGNLDLSVKTAVWYWKCYELAELNSVEKVTRRINGGLNGIDERCKLYRALMVTDND
What are the official names of this protein?
Glycosyl hydrolase family 19 domain-containing protein HI_1415.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family.
Protein: EFGM_DROAN
Sequence: MSLITRLLTASSPLRLRAMETMSRAGYSSHAKYAEHRPIDKIRNIGISAHIDSGKTTLTERILFYTGRIVEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRMGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVRERAIYFEGEHGMNLRLDEIPQDMRVESQERRQELIEHLSNADDTFGELFLEEKPFTEDDIKAALRRTCIKRTFTPVLVGTALKNKGVQPLLDAVLEYLPNPGEVENLAFVEKEGQDPEKIVLNPARDGKDAFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLAMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGIMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGNWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQGLGQADKKKRKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low (By similarity).
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1, Protein iconoclast.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THIG_PROM9
Sequence: MDNYSSLRIGGKQFSSRLMVGTGKYKSTQDMVESLSNSDTEIITVAVRRIKNDQTGDNLLEKINWKKYWMLPNTAGCVNADEAVRIAMLGRELAKLSGQEENNFVKLEVIPDKKYLLPDPIETVKAAEVLIKKGFAVLPYINADPILAKRLEELGCSTVMPLGSPIGSGQGLLNLSNIAIIIENAKVPVIIDAGIGVPSEASQAMELGADGVLINSAIAQAKNPPLMAQAINYGVKAGRQAFLAGRIKKQDFAIASSPEKNISI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYK_COREF
Sequence: MERRTKIVCTLGPAVASADGILRLVQDGMDVARLNFSHGDHPDHEQNYKWVREATDKTGRAVGILADLQGPKIRLGRFKEGSTVWETGETVRITVDDVEGTHDRVSTTYKNLAKDARPGDRLLVDDGKVGLVCVSVEGNDVICEVTEGGPVSNNKGVSLPGMDISVPALSEKDIKDLRFALKLGVDFIALSFVRSPADVELVHAIMDEEGRRVPVIAKLEKPEAVAALESIVLAFDAIMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSRIVRFAETDGRVPDLTHIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRLARLHSHLPLLVFTPDPSVRSQLALTWGAQTFLCPKVDDTDGMMREVDRALLAMDEYQKDDMMVVVAGSPPGVTGNTNMIHVHLLGEDTRIPK
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: CARA_LAWIP
Sequence: MKALLALEDGFILEGQSINGHCESSGEVIFNTGMTGYQEILTDPSYYGQMVCMTWPLIGNYGINKEDMESEKIHVSALIVKECCRNPSNWRSETSLPKFLQEYNIAGIEGIDTRALTRHIRINGAMRGIISTSITDPNDLILRVKKVPSMEGQNYVTKVAPNSPWVLYGQCVVPADIKEDGSFLWKQNKIPLIVYDYGIKWNIIRLLEGAGFDPLMVPPLFSLEQVKASGAKAIFLSNGPGDPGTLIDEIQIIRELMEYYPIAGICLGHQLLGHAVGGTTRKLTFGHHGSNHPIKNLATGHIEISSQNHGFCVNFESNNDIEVTHINLNDNTLEGFIHKTKPILAVQHHPEASPGPMDSQYFFTRFKEVVLLKLGC
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.