PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_SYNJB
Sequence: MRITLENGIPAAAASDRTEWPGLIVIAGPTATGKSRQALLLAQRLGSPLLNADSRQVYREFDIGTAKPTPAEQALWPHELIDIVDPCHTYTVAEFQQAAQARIAEAHRQGQTPILVGGTGLYIQSVTAGLGIPAVPPQPQLRRQLETWPPEIRYAWLQQLDPVAAQHIHPHDAVRTLRALEIVYTTGKPASSLRRAHPPHYPILILGLRCPMPRLEQRIARRTAEMMERGWIEEVKTLRERYGPDLPLLQTLGYAEIGAYLEGRIPEAELQPLIVRRTRQFAKRQMTWFRAMLGIQKGHAYGTLSGRGRCVALWLDCEAEDLPEQIWKQVKAWMAAPTTVETSPAAAEHRLFDP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GLNB_CYACA
Sequence: MFSKLEAIIRPFKLEEVKVRLMTFGVPGITVTNVMGCGKQIGGIERSKGVEYDSELIEKVKIEIVVMNEHIDELIEIIINAVWTGEIGDGKIFVSPVSSVIRIRTQDKDLDAI
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MGSA_SODGM
Sequence: MESTTRTIAARKHIALVAHDHCKQSLLDWVETNKAPLSEHVLYATGTTGNLMQLKTDLPVNSMLSGPMGGDQQVGTLISEGKIDMMIFFWDPLNAVPHDPDVKALLRLVTVWNILVATDRSTADFLISSPLFHQEVAIVIPDYQRYLAERLPS
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RL6_RHOPS
Sequence: MSRVGKKPVTVPSGVTATVEGQTVKMKGPKGQLQFVVHDDVDVKFEDGSVKVAPRFETNRAQALYGTARAQIANLVDGVTKGFEKKLEITGVGYRASLQGKKLQLALGYSHDVIYDIPEGITITVPKPTEINVVGIDSQKVGQVAAEIRDYRPPEPYKGKGVRYSDEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LIPA_AERS4
Sequence: MSKPVRMEPGVKLRDGDKMALIPVKFMPDPNEEVLRKPDWMRIKLPPSSQKIEHIKSTLRKNKLHSVCEEASCPNLAECFNHGTATFMIMGAICTRRCPFCDVAHGRPLALDPDEPQKLALTIKEMGLKYVVITSVDRDDLRDGGAQHFADCIKQIREHSPQTRIEILTPDFRGRMEQALEVFRETPPDVFNHNLETAPRMYRVARPGADYKWSLELLRRIKEMHPHVPTKSGVMMGLGETNEEIVQVLKDLREHGVNMLTLGQYLQPSRHHLPVKRYVPPAEFDELKDVAMGLGFSHAACGPFVRSSYHADLQAKGEEVVGYKAK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASC4_DIDFA
Sequence: MPSSEASPAAGLSEDSTRHLPRILCLHGGGTNARIFKAQCRQLSAQLKRDFRFIYAEAPWISIAGPDVLAVYGQWGPFKRWLRWSPEQPDITTQETVKELDQCLARAVEADNACGTTGEVVAILGFSQGAKVAASVLYWQQRSGQSLGLRASNSGYRFGVLLAGSSPLVDLSTCEGDSNGLSENAWPGDDMIGPRALDCDTHKLIIPTLHVHGLQDRGLRLHRALMEDFCAPESTTLIEWDGVHRVPLNRAEVSRVAGQIRKLAGLTSNS
What is the function of this protein?
Esterase; part of the gene cluster that mediates the biosynthesis of the selective antifungal agent ascochitine, an o-quinone methide that plays a possible protective role against other microbial competitors in nature and is considered to be important for pathogenicity of legume-associated Didymella species (PubMed:31554725).  The pathway probably begins with the synthesis of a keto-aldehyde intermediate by the ascochitine non-reducing polyketide synthase pksAC from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (Probable).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (Probable).  The HR-PKS (orf7) probably makes a diketide starter unit which is passed to the non-reducing polyketide synthase pksAC for further extension, producing ascochital and ascochitine (Probable).  The aldehyde dehydrogenase (orf1), the 2-oxoglutarate-dependent dioxygenase (orf3) and the dehydrogenase (orf9) are probably involved in subsequent oxidations of methyl groups to the carboxylic acid of the heterocyclic ring (Probable).  The ascochitine gene cluster also includes a gene encoding a short peptide with a cupin domain (orf2) that is often found in secondary metabolite gene clusters and which function has still to be determined (Probable).
What are the official names of this protein?
Esterase, Ascochitine biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: Y2242_MYCTU
Sequence: MNDNQLAPVARPRSPLELLDTVPDSLLRRLKQYSGRLATEAVSAMQERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAISGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRDAYVLRVAATVGQLNYPTPH
What are the official names of this protein?
Uncharacterized protein Rv2242.
What is the protein family that this protein belongs to?
Belongs to the CdaR family.
Protein: LPLT_SHISS
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETMSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_YERPE
Sequence: MSNNTTSLPAENSSHPRKGTPIRKKQREEAQQFINTLQGVTFPNSQRIYLQGSRPDIQVPMREIQLSPTQIGGSKNEPRYEDNEAIPVYDTSGPYGDPQAKLDVHNGLPKLRAAWVADRQDTEALASVSSGFTQQRLADEGLDHLRFEHLPRPRKAATGQCVTQLHYARQGKITPEMEFIALRENMGRERIRGEVLLQQHPGQAFGAHLPENITAEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLTWEMFRDTLLEQAEQGVDYFTLHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICQICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPATARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQEQAAAQAQAATPTTAAQPIDITQPINMLQSGMEKMSAEFRSRGSELYHRPANLSAEANNEPT
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y088_NEIMB
Sequence: MTPSALKKTVLLLGTAFAAASVHASGYHFGTQSVNAQSTANAAAAEAADASTIFYNPAGLTKLDSSQISVNANIVLPSIHYEADSATDFTGLPVQGSKSGKITKTTVAPHIYGAYKVNDNLTVGLGVYVPFGSATEYEKDSVLRHNINKLGLTSIAVEPVAAWKLNDRHSFGAGIIAQHTSAELRKYADWGIKSKAEILTAKPPKPNGVAEAAKIQADGHADVKGSDWGFGYQLAWMWDINDRARVGVNYRSKVSHTLKGDAEWAADGAAAKAMWSTMLAANGYTANEKARVKIVTPESLSVHGMYKVSDKADLFGDVTWTRHSRFDKAELVFEKEKTVVKGKSDRTTITPNWRNTYKVGFGGSYQISEPLQLRAGIAFDKSPVRNADYRMNSLPDGNRIWFSAGMKYHIGKNHVVDAAYTHIHINDTSYRTAKASGNDVDSKGASSARFKNHADIIGLQYTYKFK
What are the official names of this protein?
Putative outer membrane protein NMB0088.
What is the protein family that this protein belongs to?
Belongs to the OmpP1/FadL family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: B3GT4_MOUSE
Sequence: MPLSLFRRVLLAVLLLVIIWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLISNSHACGGSGPPPFLLILVCTAPEHLNQRNAIRASWGAIREARGFRVQTLFLLGKPRRQQLADLSSESAAHRDILQASFQDSYRNLTLKTLSGLNWVNKYCPMARYILKTDDDVYVNVPELVSELIQRGGPSEQWQKGKEAQEETTAIHEEHRGQAVPLLYLGRVHWRVRPTRTPESRHHVSEELWPENWGPFPPYASGTGYVLSISAVQLILKVASRAPPLPLEDVFVGVSARRGGLAPTHCVKLAGATHYPLDRCCYGKFLLTSHKVDPWQMQEAWKLVSGMNGERTAPFCSWLQGFLGTLRCRFIAWFSS
What is the function of this protein?
Involved in GM1/GD1B/GA1 ganglioside biosynthesis.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 4, Beta-1,3-GalTase 4, Beta3Gal-T4, Beta3GalT4, b3Gal-T4, Gal-T2, Ganglioside galactosyltransferase, UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: YE6A_SCHPO
Sequence: MGPSGAGTRGGQAQFQWEEVRNDKQKGRYLGQSIYAASGRWAEGKDLEWWSKGRTTQSAINSENSDKEKYKKEILEIKEREQRMLAEALGLPQPSALALTSSKAANRSSTNTEKDSRSIAHSTSRSRSTSPANRHRRKEKERTRSNHRHGSHRRHEPYRTHLSRHHRHSTTNYHSKRDDRYERRREHSPNDGGS
What are the official names of this protein?
Uncharacterized protein C6G10.10c.
Protein: VM3SA_TRIST
Sequence: MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTTLPKGALQQNYEDAMQYEFKVNGEPVVLHLEKNKELFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIQNEADSTASISACNGLKGHFKLQGETYLIEPLKLPDSEAHAVFKYENVVKEDEAPKMCGVTETNWKSDEPIKKASQLVVTAEQQRFPRRYVKLAIVADRRMYMKHQKNLKPWVFQMVNSVHQIYRSMNVLIALVYLNIWKKNDKITVQSASDVTLDLFAEWRETVLLRRKKHDCAHLLTAIDFDGPTIGRAHIASMCNSKLSVGIVQNYTEINLVNAIVMAHELGHNLGISHDGNQCNCHTCIMSAVISNPPSERFSNCSEDYHQSFLTAYNPQCILNAPSKTDIITPPVCGNELLEEGEECDCGSPENCQYQCCDAASCKLHSWVKCESGECCDQCRFTSAGTECRAARSECDIAESCTGQSADCPTDDFHRNGQPCLSNHGYCYNGNCPVMHYQCIALFGSNAIVGQDECFDFNMKGEQYFYCRKEYEKYIPCAQEDVKCGRLFCFYTNNMDICRYNYSDIGIVDHGTKCADGKVCNSNRHCVDVTTVY
What is the function of this protein?
This metalloproteinase-disintegrin-like impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like stejnihagin-A, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC2_RHDSA
Sequence: MKEKYLFIPPKPKFTNKTIDKKELKKLMAWAFSNYGTGRASYLADKIKDLGFQYATKAGLSLSVEDLRVPPTKRELLKRTNEEINLTQQKYERGEITTVERFQKVIDTWNNASEELKDEVVKYFKETDPLNTIYIMAFSGARGNISQVRQLVGMRGLMADPQGQIIDLPIKSNFREGLTVTDYIISSYGARKGLVDTALRTADSGYLTRRLVDVAQDIIIREIDCDTDRGILLKDMVSNNQILIPLQNRLLGRVLFETLHSPDSANVIAHINQDLDHNTAEFIVKSGIKSVIVRSPLTCESSRSVCQFCYGWNLAHGSLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGELAEQIRAPFDGVLRIPKSFRTRLIRTRHGEEAFVLEDSYKLDLYDSSYKKHKIEFKQGTILFLNDNEQFKKSQVIGELSTKSSMITERVTKDLNTENSGEVCFSNLYIEEKIDRQGNSITNTPKGGCLWILSGEVYNLPSYADIKIKEKQFVEEDEVLATSKVISDYGGLVRLNQSNQTSNITELQIVTSSVSLDNATIVTDDQKSTNSDPSYTLEMECGIKFHMLCSPGNKIVNSQIIAELIDTKYQTSTGGIVKYDGFEVNKKNKNKKGYEILGEGALLWIPEETHEINKDISLLLVEEGQCITAGTQIVKELYSLTEGYIQIIQENEIVKEVIVKPGKEHVRSTTSNNLNEYPKIVKPNDPDYAEYNAQGTIYIEELHYKKGNALLIRPVIEFRIDNEKIDLKTNYLTNENHHITIKPTKRVLFKDGQRVKSKYGVDLLKTYLIMSVDFDKPHLSADVEFVPAHEDDIYKLHLTVLETLQIKQDDFGESKKKSTITSLCVKQNELIKAGSTVAETHLLAHSAGFVQSINQTSQSTCKVLILTNSDEKSIDIYNQTPQVSQGDFIRSGDQIANGIIAETSGQIVEIETNKIKIRSGTPYLVSSNAILQVKNGNLVETGDTLAILVFERSKTGDIVQGLPRIEEILEARKPKEPSKLSQRPGKITLNYDSEDNKCIRILSSNGEYNEYIMSGIQKIIVSNGENILLAEPITDGAPNPHEMLGLFFNFYKERMPLYEAAKLALQKVQIYLVNEVQNVYQSQNVDISDKHIEVIVRQMTSKVKVEDGGDTTLLPGELVELQQIENINEAMTLTKGLPARYSPVLLGITKSSLNTDSFISAASFQETTRVLTEAAIEGKADWLRGLKENVIIGRLIPAGTGFNSYNDISKSFVLEKKNQMPDSYEQNQNEEQNIEDIILDDNIARNYALIENPINNFDTIEQNINQSKDI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAA_SALG2
Sequence: MNDVSKASLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSALIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITSAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCATRQLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UREE_YERMO
Sequence: MILIEHILGNVKKDPVWQAKLKDATFDLLILDQREAQKSRCRKSSTQGLDLGISLDRHVVLADGDVLAWDEENNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKHNEVYVPLTVATSMMDSVMRTHGFQHLPFRFVKGAEILPQLSNSEARLLFGGAEDSDTHVHVDSPLDEPHGSGLHVHAIHSHGDGHSHSHSHDHDHDHRHDDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1A2_BOVIN
Sequence: MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAFGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSSILVQGKEIPLDKEMQDAFQNAYLELGGLGERVLGFCQLNLPSAKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients (By similarity).
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-2, Na(+)/K(+) ATPase alpha-2 subunit, Sodium pump subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: VL2_HPV1
Sequence: MYRLRRKRAAPKDIYPSCKISNTCPPDIQNKIEHTTIADKILQYGSLGVFLGGLGIGTARGSGGRIGYTPLGEGGGVRVATRPTPVRPTIPVETVGPSEIFPIDVVDPTGPAVIPLQDLGRDFPIPTVQVIAEIHPISDIPNIVASSTNEGESAILDVLRGNATIRTVSRTQYNNPSFTVASTSNISAGEASTSDIVFVSNGSGDRVVGEDIPLVELNLGLETDTSSVVQETAFSSSTPIAERPSFRPSRFYNRRLYEQVQVQDPRFVEQPQSMVTFDNPAFEPELDEVSIIFQRDLDALAQTPVPEFRDVVYLSKPTFSREPGGRLRVSRLGKSSTIRTRLGTAIGARTHFFYDLSSIAPEDSIELLPLGEHSQTTVISSNLGDTAFIQGETAEDDLEVISLETPQLYSEEELLDTNESVGENLQLTITNSEGEVSILDLTQSRVRPPFGTEDTSLHVYYPNSSKGTPIINPEESFTPLVIIALNNSTGDFELHPSLRKRRKRAYV
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: RS7_RICAE
Sequence: MSRRHAAEKRVILPDMKYNSILLSRFINNIMKEGKKALAEKIVYSAFNKIEKKHRVDPYQTFNNAMHNVKPHLEVTSVRVGGANYQVPTHVDERRGYALASRWIINAASKRSEKMMIDKLAEELFEASNNRGVAIKKKEDTHKMAEANKAFSHFSPKKMK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PRMA_ECOBW
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDUO_MYCBO
Sequence: MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGGDRTAS
What are the official names of this protein?
Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKAI3_MOUSE
Sequence: MGCCTGRCSLVCLCALQLLSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPRYIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLPPSAHGMMDDYTYVSVTGCVVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDTCRNK
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3, Protein FAM77D.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OXLA_NAJAT
Sequence: MNVLFIFSLLFLAALESCADDRRSPLEKCFQEADYEDFLEIARNGLKETSNPKHVVVVGAGMAGLSAAYVLAGAGHKVTLLEASERVGGRVITYHNDREGWYVNMGPMRLPERHRIVREYIRKFGLKLNEFFQENENAWYYINNIRKRVWEVKKDPSLLKYPVKPSEEGKSASQLYQESLRKVIEELKRTNCSYILNKYDSYSTKEYLIKEGNLSRGAVDMIGDLLNEDSSYHLSFMESLKSDALFSYEKRFDEIVGGFDQLPISMYQAIAEMVHLNARVIKIQYDAEKVRVTYQTPAKTFVTADYVIVCSTSRAARRIYFEPPLPPKKAHALRSIHYRSATKIFLTCSKKFWEADGIHGGKSTTDLPSRFIHYPNHNFTSGIGVIMAYVLADDSDFFQALDTKTCADIVINDLSLIHDLPKREIQALCYPSIKKWNLDKYTMGSITSFTPYQFQDYFESAAAPVGRIHFAGEYTGRFHGWIDSTIMTGLRAARDVNRASQKPSKIR
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:18180850).  Shows activity on L-Leu (PubMed:18180850).  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities (By similarity).  This protein induces platelet aggregation by both hydrogen peroxide production and binding to platelet membrane proteins (that would enhance the sensitivity of platelets to hydrogen peroxide).  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino-acid oxidase, LAO, NA-LAAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHSY_VIGUN
Sequence: MVSVSEIRQAQRAEGPATILAIGTATPPNCVDQSTYPDYYFRITNSEHMTDLKEKFQRMCDKSMIKKRYMHVTEEILKENPSMCAYMAPSLDARQDIVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPQIEKPLFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIGKALSEAFDPLNISDYNSIFWIAHPGGPAILDQVAQKLGLKPEKMKATRDVLSDYGNMSSACVTFHLDEIEKSVENGLKTTGKDLEWGVLFGFGPGLSLETVVLHSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.