PharMolix/UniProtQA huggingface dataset:
Protein: RR3_PICAB
Sequence: MAQKINPLGFRLGVTQNDRSHWFAQQRNYSKDLREDQKIRTCIENYVRTHIKSSSNYGGIARVEISRKIDLIQVKIYIGFPNLLLIEGRGFQGIEKLKNDVLNMLDSVDRKLHIAIEKVAKPYRKPNILAEYIALQLEKRVPFRKTMKKAIELAEREEVEGIQIQIAGRLDGKEIARVEWDRGGRVPLQTIRARIDYCYYPVQTIYGVLGIKIWILEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVA_ENT38
Sequence: MIGRLRGIILEKQPPLVLLETGGVGYEVHMPMTCFYELPDAGKEAIIFTQFVVREDAQLLYGFNNKQERMLFRELIKTNGVGPKLALAILSGMSAHQFVNAVEREDPAALIKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPNGPTSDDAEQEAVAALVALGYKPQEASRMVSKIAKPDANSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ABAQ_ACIBT
Sequence: MDFEKDVIRTVTFKLIPALVILYLVAYIDRAAVGFAHLHMGADVGIGDAAYGLGAGLFFIGYFLFEVPSNLLLDKFGARKWFTRILLTWGLITMAMALIQGPKSFYLLRFLLGVAEAGFFPGVLYLITQWYPVRHRGKIMGMFVLSQPIAMMIAGPLAGLLLGMDGIANLHGWQWLFVAVGLPAVLLALPTFLWLPDNIDKVKWLSIEQKQWLKNELVKDEAEYDQTRHANPLHALKDKRVLLLALYYLPVTLSIYGLNLWLPTIIKQFGGGSDIQIGFLSSIPYIFGIIGLLIIPRSTDRLNDRYGHLSFLYALGACAMFLSGWLNSPVMQLAALAVVAFCLFSSTAVFWTLPGRFLTGASAAAGIALINSVGNLGGYVGPFGIGLLKEYTGNMAAGLYFLSIVMLFGLILTYIVYAKLERQKTQTVNIQKPL
What is the function of this protein?
Efflux pump that mediates resistance to quinolone-type antibiotics.
What are the official names of this protein?
Quinolone resistance transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAL1_YEAST
Sequence: MTKSHSEEVIVPEFNSSAKELPRPLAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLVVSNKFETAPTNYNLRVVEVTTAANVLAATYGVVLLSGKEGSSTNKGNLRDFMNVYYARYHNISTPWNGDIESGIERLTKMLVLVEESLANKKQGFSVDDVAQSLNCSREEFTRDYLTTSPVRFQVLKLYQRAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLVPGGPNGNIEKVKEALANEFYKVKYPKITDAELENAIIVSKPALGSCLYEL
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: COAC_MOUSE
Sequence: MEPKAPCPAAVPSEERKFRVLVGVTGSVAALKLPLLVSKLLDVPGLEVTVVTTERAKHFYSPQDVPVTLYSDADEWEMWKRRSDPVLHIDLRRWADLMLVAPLDANTLGKVASGICDNLLTCVIRAWDLNKPLLFCPAMNTAMWEHPLTAQQVAQLKAFGYVEIPCVSKKLVCGDQGLGAMAEVETIVAKVQAVLSQHGSIQQS
What is the function of this protein?
Catalyzes the decarboxylation of the cysteine moiety of 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine and this reaction forms part of the biosynthesis of coenzyme A.
What are the official names of this protein?
Phosphopantothenoylcysteine decarboxylase, PPC-DC, CoaC.
What is the protein family that this protein belongs to?
Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.
Protein: PROB_FRACC
Sequence: MRPFVTDARRVVVKVGSSSLTTAAGGLDVDRLEALVAAVLPRAGQQLVLVSSGAIAAGLAPLGLARRPRDLATQQAAASVGQSSLVHSYAAAFGRAGHQVGQVLLTATDVIRRTHYRNARTALDRLLELDVIPIINENDAVATQEIRVGDNDRLAAIVAHLVSADLLVLLSDVDGLYDANPRLGPATMVREVRSDTDLDGLTARGTGTAGVGVGGMATKIEAARMAASGGVTAIITSAANAAPVLRGEEVGTVFHPTGSRRASRLLWLAHATAPEGRLHLDSGAVAAVVRRRASLLPAGITGVEGDFAAGDPVDLVDPDGRSVARGLVAFDAAELPVMLGRSTADLAMELGPSYEREIVHRDDLVLLLPAR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPYA_ASPOR
Sequence: MRVLPATLLVGAASAAVPPLQQVLGRPEEGMSFSKPLHAFQEQLKTLSEDARKLWDEVANYFPDSMDHSPIFSLPKKHTRRPDSHWDHIVRGSDVQKIWVNNADGEKEREIDGKLEAYDLRIKKADPSALGIDPNVKQYTGYLDDNGNDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFMELGPSSIDENIKPVYNDFSWNSNASVIFLDQPVNVGYSYSGSAVSDTVAAGKDVYALLSLFFKQFPEYAEQDFHIAGESYAGHYIPVFASEILAHKNRNINLKSVLIGNGLTDGLTQYGYYRPMGCGEGGYKAVLDEATCESMDNALPRCRSMIESCYNSESAWVCVPASIYCNNALIGPYQRTGQNVYDVRSKCEDESNLCYKGMGYVSEYLNKAEVREAVGAEVGGYDSCNFDINRNFLFHGDWMKPYHRLVPGLLEQIPVLIYAGDADYICNWLGNKAWTEALEWPGQKEYASAELEDLKIEQNEHTGKKIGQVKSHGNFTFMRLYGGGHMVPMDQPEASLEFFNRWLGGEWF
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole. Note=Requires vps10 for correct vacuolar localization.
Protein: RS2_BUCAP
Sequence: MEIVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGSRNKVHIINLEKTLPMFNFALSELKKISLKKGKILFVGTKRAASKKIKETALNCNQFYVNHRWLGGMLTNWKTVRQSIKRLKDLETESQDGTFSKITKKEALIRTRELSKLENSLGGIKNMGGLPDCLFVIDAAHENIAIKEANNLGIPVFAIVDTNSNPDGVDYVIPGNDDAIRSVTLYLQAVSLSICKNQNGNSFSEMLLDSDKKMNIE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ATX3H_ARATH
Sequence: MERTSNGGMLYHEVQESNLCAVHCVNTVLQGPFFSEFDLAAVAADLDGKERQVMLEGAAVGGFAPGDFLAEESHNVSLGGDFSIQVLQKALEVWDLQVIPLNCPDAEPAQIDPELESAFICHLHDHWFCIRKVNGEWYNFDSLLAAPQHLSKFYLSAFLDSLKGAGWSIFIVKGNFPQECPMSSSSEASNSFGQWLSPEDAERIRKNTSSGSSARNKRSNDNVNQQRRNQALSREEVQAFSEMEDDDLKAAIAASLLDASAAEANLGAVGTSEKETEKQK
What is the function of this protein?
Interacts with key regulators of transcription and represses transcription.  Acts as a histone-binding protein that regulates transcription.  Acts as a deubiquitinating enzyme (By similarity).
What are the official names of this protein?
Ataxin-3 homolog, MJD1a-like, Machado-Joseph disease-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDHI_ARAHI
Sequence: MLPMITGFMNYGQQTLRAARYIGQGFMITLSHTNRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETNIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYEFATYDRHELNYNQIALGRLPMSVIDDYTIRTIWNSPQTKNG
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DPO3A_LACLA
Sequence: MFAPLNTKTEYSFLDSVVKVDDYLETAHRLGYQTVGICDVGNLHAAFRFVRKAQKFNLQPIISIELNFEWRGLPIAFSFIAKDTEGYKNLLRISTLHNYGRRQFSDIQNHLSGIALIIPETYGSLSELTELSSVADEAFIGIDQLTDKGAKFNLPTLPFPAIRYLNFADNEILAILHAVRDGVSFDESLTISSNELLQRPEAYETYFLKYFPQALKNLSALTAKIAYQFDEKLELPRFDKKRQAVEHLREEATLGLSARLEEKNLLTEVSSVNLQDLSVYQERLEKELSVIHQMGFDDYFLIVADLLRYAREQDIYCGMGRGSAAGSLVAYVLGITQVDPVQHNLFFERFLNPERVAMPDIDIDMPDDRRAELLAYMKNRYGSDHVAQIVTFSTLGKRQALRDVGKAFGMTEAELSNLTRMLVRRFGTLADEYENNQRFKAEVLKNGKLKRIYEVARRIEGMPRQTSTHASGVVLSEESLVNYVSLKPSEDLALTQYEAPDVEAIGLLKIDFLGLRNLTIISRLRDLVKRRQKIDIDPLKINLEDEDTLALFRAGNTMGIFQFENPQMRRFLRNLAPSKFDDIVDATSIFRPGPSQFIPQFVARRHGKEIVPTVDDSISEILKPTYGIMIYQEQIMQVAQAFAGFSLGKADLLRRAISKKKGSELEKLREDFLDSASHNGHSKEKAEEIYDLIERFANYGFNRSHGFAYGALAFQIAYFKAHFPDEFYEIQLRDRKREVMILDALENGFEIEKPSINLMKIGDFVKNKKIRLGLAHVQGISRDLAKWIVENQPYKDLADFVEKLPNNFHKKENILPLIQIGAFDYADSNRGKLAYNLADHANLLNYYSDDIFMASSGGGFAYHEAEDYSETEKYDFEKNLLGIGVTPHPLQNLARRFEGNFTPLAQLVKNRRMTILVEINYIRTHRTKTGQTMAFLTVSDSRENFDVTLFPEIYRQFSGELEQGKFYLISGKVTERNDELQLVTDRISPALETDRKLWLNLRDDKYNQKISQILREFPGSHQVILHYSNLKKTIQTKIYVEESEILQKRLEGYVIAGIYK
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_ECO81
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: DB129_PANTR
Sequence: MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSATISTMTPGQITYTATSTKSNTKESRDSATASPPPAPPPPNILPTPSLELEEAEEQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 129, Defensin, beta 129.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFH_MANSM
Sequence: MAQINIEITYAFPEHYYLKKFTLDEGTTVQSAILQSGILQQFTDIDLRENKIGIFSRPVKLTDSLNDGDRIEIYRPLLADPKEIRRKRAAQQAKDQEEKKKAEKSANKEN
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RNC_HALH5
Sequence: MPHSKNQRKHRHHSHSERRRQPKRLTLTAKQQQMFDELLRTLNLTFANKKLLVQAFTHSSYVNEHRIQSCKDNERLEFLGDAVLELAVSQYLYKAFEQMSEGDMTKLRASIVCEPSLAQLAEELHFGELVLLGKGEEMTGGRKRPALLADVFESFVGALYLDQGMDAVYLFLERTIYPKISEGAFSHMMDFKSQLQEFIQRDNLGHIHYEIVQERGPAHNREFVSEVVLNNETLGVGTGRSKKEAEQHAAQQALITLSQKKEQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
Protein: SARM1_HUMAN
Sequence: MVLTLLLSAYKLCRFFAMSGPRPGAERLAVPGPDGGGGTGPWWAAGGRGPREVSPGAGTEVQDALERALPELQQALSALKQAGGARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALGNCALHGGQAVQRRMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVERSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQRLVPLLDSNRLEAQCIGAFYLCAEAAIKSLQGKTKVFSDIGAIQSLKRLVSYSTNGTKSALAKRALRLLGEEVPRPILPSVPSWKEAEVQTWLQQIGFSKYCESFREQQVDGDLLLRLTEEELQTDLGMKSGITRKRFFRELTELKTFANYSTCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIHLGVHRARILTAAREMLHSPLPCTGGKPSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGFEWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRSSRDSSAGSDTSLEGAAPMGPT
What is the function of this protein?
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607).  Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:15123841, PubMed:16964262, PubMed:20306472, PubMed:25908823).  Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (PubMed:25908823, PubMed:28334607, PubMed:30333228, PubMed:31128467, PubMed:31439793, PubMed:32049506, PubMed:32828421, PubMed:31439792, PubMed:33053563).  Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:29395922).  Can activate neuronal cell death in response to stress (PubMed:20306472).  Regulates dendritic arborization through the MAPK4-JNK pathway (By similarity).  Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (PubMed:16964262).
What are the official names of this protein?
NAD(+) hydrolase SARM1, NADase SARM1, hSARM1, NADP(+) hydrolase SARM1, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2, MyD88-5, SAM domain-containing protein 2, Tir-1 homolog, HsTIR.
What is the protein family that this protein belongs to?
Belongs to the SARM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Cell projection, dendrite. Synapse. Mitochondrion. Note=Associated with microtubules.
Protein: GLMM_STAAT
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIALDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: FSHB_PANTR
Sequence: MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGHCYTRDLVYKDPARPNIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE
What is the function of this protein?
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer.  Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways.  Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
What are the official names of this protein?
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted. Note=Efficient secretion requires dimerization with CGA.
Protein: ASSY_BURM9
Sequence: MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEEVTIRFEEGRPVALNGVEYKDAVALLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSIIGTRSPNLTYQPERLSMEKVQSMFSPRDRIGQLTMRNLDITDTRDKLRIYSQVGLLAAGESSALPKLKEDESGN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_VIBCH
Sequence: MALWGGRFTQAADSRFKSFNDSLRFDYRLAEQDIVGSIAWSKALVSVNVLSVQEQQQLEQALNHLLQSVQQDPEQILASDAEDIHSWVEQKLIEQVGDLGKKLHTGRSRNDQVATDLKLWCRDQGVHLLLALKTLQQQLVAVAAEHQSTVLPGYTHLQRAQPVTFTHWCLAYLEMFERDESRLTDALARLNTSPLGSGALAGTAYAIDREVLAADLGFTRATRNSLDAVSDRDHVMELMSVASISMLHLSRLAEDMIFYTTGEAGFIELADTVTSGSSLMPQKKNPDALELIRGKTGRVYGALAGMMMTVKALPLAYNKDMQEDKEGLFDALDTWFDCLQMAGLCFDGIKVNAARTLEAAKQGYSNATELADYLVAKGIPFREAHHIVGVAVVAAIGKGVALEELCLAELQQFSPLIEQDVYPILTIESCLEKRCALGGVSPKQVAHALQQAQARVKS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_BRADU
Sequence: MSALANHAFAKMNGIGNEIVVVDMRDSTAKVTPDDARAVASAQGGVPYDQLMVLQKPRLDGTEAFISIYNNDGSEAGACGNGMRCVVRRIFEKTGQATATFETAAGLLNAWQGPAPDLYTVDMGVPKFGWQDIPLAEEFRDTRYIELQIGPIDNPILHSPSVVSMGNPHAIFWVDDVNAYDLARFGPLLENHPIFPERANITLAHIVDRDHITIRTWERGAGLTRACGSAACATAVAAARLKRAERNVEITLPGGKLGIEWRERDDHVLMTGTATFEYEGNFDPALFAPAG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_CYTH3
Sequence: MLDVRPDEVSAVLRQQLSNSLTEAQLEEVGTVLQVGDGVARIYGLTKAQAGELLEFEGGLKGMVLNLEEDNVGAVLLGEYSAIKEGSTVKRTKQIAFVNVGEGMVGRVVDTLGNPIDGKGPITGELYKMPMERKAPGVIYRQPVTEPLQTGIKAIDAMIPIGRGQRELIIGDRQTGKTTVALDAIINQKEFYDRGEPVFCIYVACGQKASTIAGIVGTLEKHGAMAYTVVVAATASDPAPMQYFAPFTGAAVGEYFRDTGRPALVVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYLHSRLLERAAKINKSDEIAAAMNDLPESLKGIVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLEINLFNSGVRPAINVGISVSRVGGNAQIKSMKKVAGTLKLDQAQFRELEAFAKFGSDLDASTKLTIERGRRNLEILKQPAFSPVSVEEQVATIYVSTNGFMDSVVVNKVRDFEKDFLTVLRTSHKDTLKEIKSGKIDDAITEVLKKVAKEVAVKYSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRUB_CORGL
Sequence: MNAPAPKPGLVIVDKPAGMTSHDVVSKLRRAFSTRKVGHAGTLDPMATGVLVVGIERGTRFLAHMVASTKAYDATIRLGAATSTDDAEGEVISTTDASGLDHSTILAEIVNLTGDIMQKPTKVSAIKIDGKRAHERVRDGEEVDIPARPVTVSVFDVLDYHVDGEFYDLDVRVHCSSGTYIRALARDLGNALQVGGHLTALRRTEVGPFTLNDATPLSKLQENPELSLNLDQALTRSYPVLDITEDEGVDLSMGKWLEPRGLKGVHAAVTPSGKAVALIEEKGKRLATVFVAHPNTL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y9745_DICDI
Sequence: MVRNSEITLEQIFKEGRINLENDDYNCVICSFPLFDGLQCKRGHGACKSCWEKIIGENGKKECHSCRISIKSLDDLSKNLYLEKEIFKQKVACLNNGREKFGNTLVIKSDGGCKRQDIPIEKLLHHIKNECGYLLIDCKYSRDCKYYKQISLEQHQNECQFMSIHCPALCGKKDSRMNINKHLETPNSCKPLISINNSNNSNGNGNGIDDESIIKLSNSIVEIQKSYQNQIKKIKENSESEIAALKDSLYYSKSRIKNLEDEVEELKDRFSTLESMINKLDDSATSRSGTILINGWKMKLKSLDVGHSIVEEQFYIGTNRFYIRIYPFGDSYDNQGYVTVKLGRIDGEEYHLDIGLKVSIKGFDNKKKVLLSYYPGDIAHNIDQLVETWETSKEFKMILHFKVDLKPKIK
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0279745.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_COLP3
Sequence: MSKISKILAREIMDSRGNPTVEADVYLESGAFGRAAAPSGASTGSREALELRDGDKARYLGKGVLKAVAAINVNIQAALIGQSALDQANIDQIMIDLDGTENKEQFGANAILAVSLANAKAAANEKKVQLFEHIADLNGTPGVYSLPLPMMNIINGGEHADNNVDIQEFMVQPVGAKSFREALRMGAEIFHALKKVLSSKGMSTSVGDEGGFAPNLESNADALAVIKVAVEAAGYELGKDVTLAMDCAASEFYDADKGIYDLTGEGKQFTANEFSDFLGELCKEYPIVSIEDGLDESDWDGFKYQTDLLGDKVQIVGDDLFVTNTKILARGIENGIGNSILIKFNQIGTLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEEFLGDKAIFNGLSEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL14_ORITI
Sequence: MIQMQTILNVADNSGAKEVMCIKVLGGTHHMIAHLGDVIVVSIKSSIPKGKVKKGEVCKALIIRTKCGVTRHDGSNIKFDSNDVVLLNKQGEPFGTRIFGSVPRELRVKNFSKIVSLAEEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PG077_RABPU
Sequence: MAEFEDQLVFNSISARALKAYFTAKINEMVDELVTRKCPQKKKSQAKKPEVRIPVDLVKSSFVKKFGLCNYGGILISLINSLVENNFFTKDGKLDDTGKKELVLTDVEKRILNTIDKSSPLYIDISDVKVLAARLKRSATQFNFNGHTYHLENDKIEDLINQLVKDESIQLDEKSSIKDSMYVIPDELIDVLKTRLFRSPQVKDNIISRTRLYDYFTRVTKRDESSIYVILKDPRIASILSLETVKMGAFMYTKHSMLTNAISSRVDRYSKKFQESFYEDIAEFVKENERVNVSRVVECLTVPNITISSNAE
What is the function of this protein?
DNA-binding protein which binds to the hairpin form of the viral telomeric sequence.  Required for the production of mature virions (MV).
What are the official names of this protein?
Telomere-binding protein OPG077, Telomere-binding protein I1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG077 family.