PharMolix/UniProtQA huggingface dataset:
Protein: SPAST_DROVI
Sequence: MVRTKNQSSSSSASSSTKSPVKISGGGGGGGGSSSSTNRSRSCSEALIDDGKSSSKLSSNRQRTTTTITTTTTTPGSSPDDDTTDADLTPTSGNVPRGGQSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRSPHRRDCNIEIVVQNSKEQQAIICPLEGSGVNIEQAQILPQRQRALQTLEMAASRGGTGAGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHEKMQTNLSMARDRLHFLALREEDLQMQRLSLKEQPKKQLPHKFKQPMLVGQTTTSSGSSSSSRASAEPPKITLRSSGYGPKTGGATTSKAVPAASGRKLTIGNKRPGNLAVANKSQTLPRNLGSKTTSTSVGAALQRQPGKTAATPPAVRRQFSSGRNTPPQRSRTPINNNAASGSGSGASTPLISVKGVEQKLVQLILDEIVEGGAKVEWSDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSNEHEASRRLKTEFLVEFDGLPGNPEGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPGVQTRELLLSRLLQKQGSPLDTEALARLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRPITEKDFHNSLKRIRRSVAPQSLNSYEKWSQDYGDITI
What is the function of this protein?
ATP-dependent microtubule severing protein.  Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle.  Regulates microtubule stability in the neuromuscular junction synapse.  Involved in lipid metabolism by regulating the size and distribution of lipid droplets.  Involved in axon regeneration by regulating microtubule severing.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome. Lipid droplet. Note=Forms an intramembrane hairpin-like structure in the membrane. Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules. Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles.
Protein: HFQ_BRASO
Sequence: MAADRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDASA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CLSB_SALTI
Sequence: MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHAALLKAAQRGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADILQFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAMRKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMETQDRVDPENSGVKP
What is the function of this protein?
Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase B, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEC_ALIFM
Sequence: MSTAIVVFSGGQDSTTCLIQALTQYDHVHCITFDYGQRHNQEIEVAKKVAIELGAASHKVMDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAEAVLTGVCETDFSGYPDCRDEFVKSINQSLVLGMDRQLEIKTPLMWLNKAETWALADKYGKLDYVRNHTLTCYNGVIGDGCGDCPSCDLRKNGLDAYLENKESVMADLESKL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: LRK18_ARATH
Sequence: MAPGLDLIWMVISFLLLIHLSSQQETGFSFNGFRQGDLHVDGVAQILPGGLLRLTDTSEQKKGHAFFRQPLVFNSSEPLSFSTHFVCAMVRKPGVTGGNGIAFFLSPSMDLTNADATQYLGLFNTTTNRSPSSHIFAIELDTVQSAEFDDIDNNHVGIDVNSLTSVESAPASYFSDKKGLNKSISLLSGDSIQVWVDFDGTVLNVSLAPLGIRKPSQSLISRSMNLSEVIQDRMFVGFSAATGQLANNHYILGWSFSRSKASLQSLDISKLPQVPHPKMKTSLLLILLLIVLGIILLVLLVGAYLYRRNKYAEVREEWEKEYGPHRYSYKSLYKATKGFHKDGFLGKGGFGEVYKGTLPQEDIAVKRFSHHGERGMKQFVAEIASMGCLDHRNLVPLFGYCRRKGEFLLVSKYMPNGSLDQFLFHNREPSLTWSKRLGILKGIASALKYLHTEATQVVLHRDIKASNVMLDTDFTGKLGDFGMARFHDHGANPTTTGAVGTVGYMGPELTSMGASTKTDVYAFGALILEVTCGRRPVEPNLPIEKQLLVKWVCDCWKRKDLISARDPKLSGELIPQIEMVLKLGLLCTNLVPESRPDMVKVVQYLDRQVSLPDFSPDSPGIGIVTPVLVGGSSTVISNISSPVTEFITHSIQYGIGR
What is the function of this protein?
Involved in resistance response to the pathogenic fungus Alternaria brassicicola.
What are the official names of this protein?
L-type lectin-domain containing receptor kinase I.8, LecRK-I.8.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPB_NEIMB
Sequence: MSQGKIVQIIGAVVDVEFPRDMIPRVYDALKLDENGLTLEVQQLLGDGVVRAIAMGSSDGLKRGMTVSNTGAPITVPVGKGTLGRIVDVLGTPVDEAGPIDTDKSRAIHQAAPKFDELSSTTELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDENGKGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTQTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPMVLGQEHYDVARGVQSTLQKYKELRDIIAILGMDELSDEDKLTVMRARKIQRFLSQPFHVAEVFTGSPGKYVALRDTIAGFKAILNGEYDHLPEQAFYMVGSIEEAVEKAKTLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UNG_BACC7
Sequence: MENVLKNDWGPLLAPEFEKEYYRKLADFLKEEYSTHVVYPKKEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSVQPGIKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNTKHHIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEREIDWEIPNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_UREP2
Sequence: MGQKVNPNGLRFGINKQWLSRWVPTDQLQMAKWLVEDDKIRKYLSTKYKNAGIDHVEIERDQQRVNVYVYAVQSGLLIGTEASEKKLIELAINKIVGRKQLVSLKVVEVQIPELQASLMAREIADAIENRVSFRIAQKMVIKKVLKAGARGIKTHVSGRLGGVEMAREEGYTQGVMTLHTLRADIDYSMQEAHTTYGIIGVKVWINRGELFGNKLVNSVAHAANKEFSRSSKPKKGSFNRSSRSKNTKPAPKQAVSE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MUTS_LISMH
Sequence: MTEYTPMIKQYLEIKDKYQDAFLFFRLGDFYEMFFEDALNASQILEITLTGREGGTKEKIPMCGVPYHSASGYIDTLIEKGYKVAICEQVEDPKTTKGMVKREVVQLISPGTVMDERGLKAKENNYIASLYCYEGKEYGFAYSDLSTGELKSTVIEASEDRLINELTTLSTRELIVSASEKEVLSDVMKEQLGLTFSVHEEDTIPLENEKLVTRHMSLSEKRAIGKLLHYLKETQKRDLGHLQQAVHYETSNYMKMDYYSKRNLELAESIRGKGRQGTLLWLLDNTQTAMGGRMLKQWIDRPLIDRNKIIERQNDVSELMANFFERLELVENLKNVYDLERLAGRVAYGNVNARDLIQLRNSLYQIPRIRATLLSMNSKSLTELANQLDPCEELTEKLEEAIMDSAPISIREGGIIKDGYNSQLDTYRDASRNGKTWIAELERKERELTGIKTMKVGFNRVFGYYIEVTRANTHLLPEGRYERKQTLTNAERYITPELKEKEKLILDAEEKSMELEYQLFTEVRELVKDYIERLQKLAKSVSEIDCLQSFADISEKNHFIRPTLSEDGSLHVKQGRHPVVEKVMGAQSYVANDCDLDRNREILLITGPNMSGKSTYMRQVALTAICAQVGCFVPAEEATLPIFDQIFTRIGAADDLIAGQSTFMVEMLEARNAIVHATKDSLILFDEIGRGTATYDGMALAQAIIEYIHENVHAKTLFSTHYHELTDLEKELHGLQNIHVSAVEENGKVVFLHKIKEGPADKSYGIHVAELAELPKSLIERASRILEQLENDDKKIVITNDKQPEEIHEEVQLSMFPVEPEKKASSKETKLLKEIASMNIMQMTPMDAMNKLYELQSKIH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FABA_PSEE4
Sequence: MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISEEGGKFGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPSAKKVTYNIHIKRVLKGKLNMAIADGSVSVDGREIYTAEGLRVGVFTSTDNF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_ENT38
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVISGALNVLLPGETEWKVYTAGQVFNVPGHSEFHLQVAEPTSYLCRYLK
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: NADE_STAS1
Sequence: MSNLQDIVVKEMKVKPSVESKSETRHIIQFIKNYVQSHSFIKSLTLGISGGQDSTLAGKLCQLAVNELKEDGNDCEFIAVKLPYGEQKDAAEVEDALTYIQPDKIITVNIKPAVDQSIQSLKEAGVNLTDFQKGNEKARERMKVQFSIASKQKGIVVGTDHSAENVTGFYTKYGDGAADIAPLFGLNKRQGKQLLAYLAAPKHLYEKTPTADLEDDKPQLPDEEALGVSYDDIDDYLEGKSVSSESKEIIENHYIKNAHKRELAYTRYTWPKN
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: DLGD_SALDC
Sequence: MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNRRILPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGATRDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDNRRHGITIDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_BURP6
Sequence: MTDRIVPATLVFREDGTVVSPLYGDIYHSAAGALAQADHVFIRGNGLPERWRHERAFTIIETGFGTGCNFLATWAAWRADPSHCERLHFVSVEKHPFAREDLRRAAAHIVAYTTITPIAPLVDELANAWPALTPGVHRLEFDDGRVTLTLVFGDALDVLPNLALRAHAFYLDGFAPSKNADLWSPAIFKSLAKLADERATFATYTSSGAVKRALDEAGFAYRKVDGFAGKRAMLVGEFAPRWRVRRHEPPRAFSTDIRDAIVIGAGLAGCAVVERLAARGWHVTLIERRERIASEASGNPAGVFHPMIARDDNLAARLSRAGFLHALNRWRALERAGHAFSRSTHGLVQLATSDNEFERMRESIDALGVPAELASALSRDDARALLRTDVAHGGWLFAQGGSISPAALAAAQCAAAGDRLSRIVGVEIARLERGGDGRWRALDASGATIAQASVVVVANAADAARIAGLRHAPTQRVRGQLTLLPPGSAPAVPLPVIGDGYVVPLANGVTLTGATYEPDDTDATPREAGHRENLERLERLLPAFSANALDAGALAGRVGFRCVASDRLPLVGELGDEAAAAREAAALTGARLRDVPRATGLYGAFGYGSRGLVWAALGAELIAAQIDGEPWPLERELAEAIDPARFLVRALRHGRVA
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU2_DROSE
Sequence: MCSIGEDDFGDDGATHAMVVESLPLGIVLSPGNCSKCDVNSGELYKLNFRTAECRECFLAYARHKFRAALGAAKILPRNAEVLLVLDGSAESLVLLDMLHFAQTQNTFKRLHCNARVVYVEEQKVQGRDPVHLEALQNLSTQYAPFDFYVIELGALPSSMQRIKDYSPSLNANNELIHKLQKLRSLTARQDYLQQQRKNLICSVAQCLQCTHVFESNISVDLATQLLTAIALGRGGSAALDVALLDDRLSGDVKLLRPLKDLNEQEIQFYIHAQRLKPLFEKGSCFGREHGQTASLQNLTSAFVANLQQNYASTVSTVFRTGDKIAANSNPEQSSCVHCRSTLDSEISDTLLAIEYSRTVSEAGVSLYKSGQDLEGLAKKRLENKDGLCHACRAIQAELDSGNLL
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEMA_STRGC
Sequence: MSFIITIAVIVVIVLFVISVYNSLVRARMQTQEAWSQIDVQLKRRNDLLPNLIETVKGYGKYEQATLEKVTQLRAQVASASSPADAMKASDALTRQISGIFAVAESYPDLKANENYLKLQEELTNTENKISYSRQLYNSVAGNYNVKLQAFPSNVIAGMFAFRPADFLSTPEEEKAVPKVDFGSNGLGE
What are the official names of this protein?
Protein LemA.
What is the protein family that this protein belongs to?
Belongs to the LemA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLMU_BARBK
Sequence: MVRNCLSIVLAAGEGTRMKSPLPKVLHKIAGLPLVCHVIKQIELAGSLQLAVVVGSGAEDITKVVQSFTKNAMIFEQKERLGTAHAVLSARLALQEEVDDILIVFGDTPLIEHSSLVRIRAFLADGADVVVAGFYASDPTGYGRLIKKNGKLITIVEEKDASDEEKKVSLCNGGIMALNGKYALSLLNKIDNNNMQQEYYLTDVVSIASRQNLNIQVVEIPFDNVIGINNCFELFEADALWQKRKARDLMLSGVTILKPESVYFSYDTEIEPGVLIEPNVYFGPGVKIQSGAVIRAFSYLEGAVVGRDAQIGPYARLRFGTELERSVKVGNFCEIKQAKVGEFSKINHLSYIGDTEIGTNTNIGAGAITCNYDGFNKHKTVIDDDVFIGSNSVLVAPLSIGKGSYIASGSVITEDVPINSMVFGRARQVIKEDRAIKLRAHLSKNKRNK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_VIBC3
Sequence: MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVVKCQVHAGGRGKAGGVELHDTKEGVKAFAQKWLGKNLVTYQTDANGQPVSKILVEEASNIANELYLGAVVDRSTRRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGRELAFKLGLQGDQIKQFVKIFMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNAMYRQPKLRQMHDASQEDAREAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDTNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVSVPVVVRLEGTNAELGRKVLAESGLDIIAAVSLTDAAQKVVAAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CSPB_LISIN
Sequence: MQTGTVKWFNSEKGFGFIEVEGGDDVFVHFSAIEGEGFKTLDEGQSVEFEIVEGQRGPQAEKVTKL
What are the official names of this protein?
Cold shock-like protein CspLB, CspB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_POLNS
Sequence: MSKLFQARFATTVNDTHYLPATPLREVAFAGRSNAGKSSAINVLCNQKRLAFASKTPGRTQHINYFGLFAKDDLLAYLVDLPGYGYAAVNHETKYHWNTLLSDYLQEREQLVGVVLIVDSRRGITDLDEQMIEWFVPTGKPTHVLLSKCDKLNKSECKHTLEAVRKQLQQYDPALPDGNGESKQLTAQLFSSTKRIGLEEADNTVIKWLFEAETNEDEITN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SOL1_YEAST
Sequence: MTTTVPKVFAFHEFAGVAEAVADHVIHAQNSALKKGKVSRSTQMSGTSLNGNGNTESKTMERVNSVRSNASSRGGSEDGATKKLKKEKERRFKIALSGGSLIQVLHEGLLKRDDVQWGKWDIYFADERLVPFSSSESNYGLAKRKIFDLIDTEKYGTPKIYHIDESLINDPQECADNYEKILIKGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQENLRENLAWVIPVENAPSGPSNRISLTIPVICHSHRVTFVVEGATKAPVIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALKDVFVIKKKYKFYDDENLTE
What is the function of this protein?
May be involved in regulation of tRNA subcellular distribution.
What are the official names of this protein?
6-phosphogluconolactonase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NRFA_ECO57
Sequence: MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGCADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BTF3_CAEEL
Sequence: MDSKAIAERIKKLQAQQEHVRIGGKGTPRRKKKVIHKTAAADDKKLQSNLKKLSVTNIPGIEEVNMIKDDGTVIHFNNPKVQTSVPANTFSVTGSADNKQITEMLPGILNQLGPESLTHLKKLANNVTKLGPDGKGEDEDVPELVGDFDAASKNETKADEQ
What is the function of this protein?
May be a general transcription factor that can form a stable complex with RNA polymerase II (By similarity).  May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) (By similarity).  In response to heat stress, plays a role in modulating the unfolded protein response by negatively regulating the accumulation of proteins such as the chaperone protein hsp-4 in the endoplasmic reticulum (PubMed:22957041).  Required to suppress apoptosis in neuronal and intestinal cells to promote development (PubMed:12944970).
What are the official names of this protein?
Transcription factor BTF3 homolog, Inhibitor of cell death 1, Nascent polypeptide-associated complex subunit beta, NAC-beta.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion.
Protein: NQRD_YERPS
Sequence: MADSKEIKRVLLSPLFDNNPIALQILGVCSALAVTTKLETALVMTLAVTLVTAFSSFFISLIRNHIPNSVRIIVQMVIIASLVIVVDQVLRAYAYEISKQLSVFVGLIITNCIVMGRAEAYAMKSPPIESFMDGIGNGLGYGVILVLVGFVRELVGSGKLFGVTVLETVQNGGWYLPNGLFLLAPSAFFIIGLLIWGLRTLKPAQIEKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_CORU7
Sequence: MAIRKYKPTTPGRRASSVSEFSEITRSTPEKSLLRPLSKTGGRNVHGHITTRHKGGGHKRRYRVIDFRRNDKDGVVAKVAHIEYDPNRTANIALLHYRDGEKRYIIAPRGLKQGALVESGPNADIKVGNNLPLRNIPAGTTIHCVELKPGGGAKMARSAGASIQLLGKEGKYAVLRMPSSEIRRVDIRCRATVGEVGNQEQINIRWGKAGRMRWKGWRPTVRGAAMNPVDHPHGGGEGRTSGGRHPVSPWGQLEGRTRRPNRPSDKMIVRRRRPNKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: VG08_BPP21
Sequence: MRDFQNAFDAALAGVDSTIVEVMGISAQFTSGAQRGGEVHGVFDDPESLGFASSGI
What is the function of this protein?
Is needed for attachment of the tail to the head.
What are the official names of this protein?
Tail attachment protein, Head protein gp8.
What are the subcellular locations of this protein?
Virion.
Protein: NUSB_CALS4
Sequence: MNRTEAREWVVKMLYQYDVSKLPLEKIFENFYEEHDPGEQKEYIEGTVRGTVEHLEEIDREIEKYSKDWPLYRMPRIDLAILRCSMYEMLYGNIPVSISINEAVEIAKKYSTDDSPSFINGLLGAFVREKGLEEGEANDN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.