PharMolix/UniProtQA huggingface dataset:
Protein: Y742_CHLMU
Sequence: MAGHSKWANTKHRKERADHKKGKIFSRTIKELISAVKMGGPDPKSNARLRMIIQKAKDQNIPNENIERNLKKASSADQKNYEEVTYELYGFGGVGIIVEAMTDNKNRTASDMRVAVNKRGGALVEPGSVLYNFSRKGACYVPKSSIDEASLLTHVIDCGGEDLDSEDEEFFLVLCEPTDLASVKEALLAKGVTCSEEKMIYVPLRLVDCDEEAGKSNLALIEWLENIDDVDDVYHNMT
What are the official names of this protein?
Probable transcriptional regulatory protein TC_0742.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXAH_BACSU
Sequence: MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSMLGKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLYVRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIPFMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNPLNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDKEICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYHYGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKKTKV
What is the function of this protein?
Involved in transport.
What are the official names of this protein?
Uncharacterized protein YxaH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYL3_HUMAN
Sequence: MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 3, Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular myosin alkali light chain, Ventricular myosin light chain 1, VLCl, Ventricular/slow twitch myosin alkali light chain, MLC-lV/sb.
Protein: VP3_GFLV
Sequence: MDSYVTVDPSFHSPRISLEILVPTKYAKLFTLKQLSRMLALSCKHRARQAANPVSKRTSRDRNGSKTMGQGPSAVAPQVSKGHNQQVDGGVCLAPVKSKRAVRREKRRTAAKKATNKAKTETKLVKKGGSSIHAPKAPKRTSYLSSLLSSPSGAKAKMGALSKPPQTKNAPDANEGGFTLTAITPAECRAEARRRFHPITGSSRGPYGFCTRSREGCGVCADCVEKKAHLDFNRSFDTIGTSRVIRVDSMMEEVAEDLASPSVLEPSGFWAPAEKQAPSGEGHSRRRCDVVTLARVTPVLRMLRKVDPTLVDNRLLWEAAFRTVFPQRKCVYPHGCFCDRG
What are the official names of this protein?
Protein P3.
What is the protein family that this protein belongs to?
Belongs to the nepovirus protein P3 family.
Protein: BIOD_BURCJ
Sequence: MTAPLSLFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYQRDGVWRNEDADQLDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGIRLGCISHALLTADAIRQRGLALAGWVANHVDPAMSFADENVATIRDWLAREHRAPLVGRIAHMTPAAPESAAAMLDIAALVESLRAARP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STRPF
Sequence: MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVIAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEIFDQRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN_THEON
Sequence: MGVQIGELIPRKEIELENLYGRRVAIDAFNAIYQFLSTIRQRDGTPLMDSQGRITSHLSGLFYRTINLMEAGIKPAYIFDGKPPDFKKRELEKRREAREEAEEKWYEALERGDLEEAKKYAMRATRVNEGLINDAKTLLELMGIPVIQAPSEGEAQAAYMAAKKKVYASASQDYDSLLFGAPKLVRNLTITGRRKLPGKNVYVEVKPELIVLEEVLKELSIDREKLIEMAILVGTDYNPGGIKGIGPKKALTIVKRTKDPLKKYQKESEVDLYAIKEFFLNPPVTDDYELKWREPDEEGIIKFLCDEHDFSEERVKNGLERLKKAVKAGKQSTLESWFGRR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: YHAM_SHIDS
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAASVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLSVLSRTTLAEILKFVNEVQFAAIRFILDSAKLNCALSQEGLSGNWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLLHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: IF4E1_SOLHA
Sequence: MAAAEMERTMSFDAAEKLKAADGGGGEVDDELEEGEIVEESNDTASYLGKEITVKHPLEHSWTFWFDNSTTKSRQTAWGSSLRNLYTFSTVEDFWGAYNNIHHPSKLIMGADFHCFKHKIEPQWEDPVCANGGTWKMSFSKGKSDTSWLYTLLAMIGHQFDHGDEICGAVVSVRAKGEKIALWTKNAANETAQVSIGKQWKQFLDYSDSVGFIFHDDAKRLDRSAKNRYTV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection (e. g.  pepper mottle virus (PepMoV), potato virus Y (PVY) and tobacco etch virus (TEV)) by recruiting viral RNAs to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1, eIF4E-1, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KCNQ3_RAT
Sequence: MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGTGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMTEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSESGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT
What is the function of this protein?
Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.  Therefore, it is important in the regulation of neuronal excitability (PubMed:9836639).  KCNQ2-KCNQ3 channel is selectively permeable to other cations besides potassium, in decreasing order of affinity K(+) > Rb(+) > Cs(+) > Na(+).  Associates with Na(+)-coupled myo-inositol symporter SLC5A3 forming a coregulatory complex that alters ion selectivity, increasing Na(+) and Cs(+) permeation relative to K(+) permeation (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily KQT member 3, KQT-like 3, Potassium channel subunit alpha KvLQT3, Voltage-gated potassium channel subunit Kv7.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.3/KCNQ3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDIP1_XENTR
Sequence: MASDPPPPYPGGPSAPLLEEKQGLPRMEEPRAAPYPQAMPFAPPDCGPPPYDANPGYIAPNPGFYPPPGPYAPMGYYPPTPGQFQPPYPSQYPSPGAQGTAVIVPPGPSSTSAATTVTSTTTTVTVLQGEIFQGSPVQTVCTNCQQPITTKISHDIGLMNFLLCCFCCFVGCDLGCCLIPCIINDLKDVTHSCPNCKYHIYTYRRMC
What is the function of this protein?
May act as a p53/TP53-apoptotic effector.
What are the official names of this protein?
Cell death-inducing p53-target protein 1, LITAF-like protein.
What is the protein family that this protein belongs to?
Belongs to the CDIP1/LITAF family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: URE1_PROHU
Sequence: MKTISRQAYADMFGPTTGDRLRLADTELFLEIEQDFTTYGEEVKFGGGKVIRDGMGQSQVVSAECVDVLITNAIIIDHWGIVKADIGIKDGRITGIGKAGNPDVQPNVDIVIGPGTEVVAGEGKIITAGGVDTHIHFICPQQAEEGLISGVTTFIGGGTGPVAGTNATTVTPGIWNMHRMLEAVDELPINVGLFGKGCVSQPEAIREQIEAGAIGLKIHEDWGATPMAIHNCLNVADEMDVQVAIHSDTLNEGGFYEETVKAIAGRVIHVFHTEGAGGGHAPDVIKSVGEPNILPASTNPTMPYTINTVDEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDMGAISVMSSDSQAMGRVGEVVMRTWQCAHKMKLQRGSLAGDTAENDNNRIKRYIAKYTINPALAHGIAHEVGSIEKGKLADIVLWDPAFFGVKPALIMKGGMVAYAPMGDINAAIPTPQPVHYRPMYACLGKAKYQTSMIFMSKAGIDAGVPEKLGLQSLIGRVEGCRKVTKASMIHNSYVPHIELEPQTYIVKADGVPLVCEPATELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_SULDN
Sequence: MLFSAPLKSNSKKIMLLGSGELGREVAIEAQRLGLEVIAVDRYQNAPAHSVAHRSYVVNMQDKDALLEIIYREKPDYILPEIEAISIDALFEAEDKGYNVIPNANAVSKTMNRKNIRTFAAEVLELKTGAYEFVTTKEMLVSAAGRLGFPCVIKPVMSSSGHGQSVARSASDIDASWEIAKEARGDASELIVEAFVDFDYEITMLTARNGKETVFCEPIGHEQRDGDYVFSWQPMQMSEIAKQRAEDMAKKITDGLGGRGLFGVELFIKGDEVYFSEVSPRPHDTGMVTLITQSQSEFALHLRAVLGLPLEFTFYGEGASAAFKSEVHNFSPVIHVDESLFSKNSFVRIFGKPEAHKGRRLAVALVFDKAEQALQRARELITKVKDS
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ACRE_ASPA1
Sequence: MHRELKEFSHPHGSTGIYEDNLQVDVLIVGAGFSGIYMLHELRKQGLKTVVYEAGSDLGGTWRFNCYPGARVDSQVPLYQFSIPETYKDWTWSTNYPDYKELRAYFDHVDKVLDIKKDVAFGSVVVDAQFDTSQSRWVVKTQDGRTAYAKYFIAAAGVSSKRYIPEWEGIENFKGPIHHTSFWPEHEVDVRGKRAAIIGTGASGVQVTQAWGPQAGHLKVFLRSPNYSIPMRRKELTADEQNQLKPIYPQLFDLREKTFTGALVDFSERSALEDSEAEREAFYEQRYQTGGFDFSTANYKDTMLNPVANRYLYDFWAKKTRARLNDERVKDLLAPVEPPYFFGGKRSSLETDFYEQFNRDTVELVDAKSNPIVGFTENGIKMQDGTVHEVDVVCLATGFDTTTGSMINLGVRSIHGTTLQEDWSQAAETYLGLTVSGYPNLFHLYGTHAPTLFSQAVTTIEVQGRWIVDAIKQMERQAIRSINPSREAAHAWKLQIRAFQNASFFPTVHSTYMGGSIPGKPFELVSYPAGMPMYARQIRDALPTFPGFEVVKADGEKVENLAPGGLEATTNFFERLFGMPPSSAKEDLAKQDH
What is the function of this protein?
FAD-binding monooxygenase; part of the cluster that mediates the biosynthesis of acurin A, a highly reduced polyketide coupled to a serine via a peptide bond (PubMed:32234543).  The activities of the highly reducing polyketide synthase acrA and the nonribosomal peptide synthetase acrB are collectively responsible for the synthesis of the acurin A core structure with a heptaketide backbone produced by acrA covalently fused to a L-serine by acrB (PubMed:32234543).  After the formation of the PK-NRP hybrid product, it is detached from acrB by reductive release to set up the formation of the lactam ring by aldol condensation (Probable).  The hydrolyase acrC then catalyzes water loss to generate a double bond in the ring (Probable).  This double bond is probably reduced, which is followed by three oxidations at C-22 to generate the carboxylic acid moiety, involving probably the FAD-binding monooxygenase acrE and the cytochrome P450 monooxygenases acrD and acrF (Probable).  Finally, a last methylation step performed by the O-methyltransferase acrG leads to the production of acurin A (Probable).
What are the official names of this protein?
FAD-binding monooxygenase acrE, Acurin A biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: GLXK_HALH5
Sequence: MNTIVIAPDSFKESMTALQAARAIEKGFRRVIPNANYRLIPMADGGEGTVQSIVDALQGERKVVKVEGPLGDTVEAEYGLSGDRKIAVIEMAQASGLHLVPKEKRNPLWTSTYGTGQLLIDALDEGVEQIILGIGGSATNDGGAGMAQAVGVRLLKENGEPIGKGGGKLKELARIDMSKVDPRIQQVKLQVACDVDNPLVGEKGAAVVYGPQKGATRATIRELDEQLLHFANIIEEELGKEVASIPGAGAAGGLGAGLIAFLDAKLIPGVELVLQATNFHELVKDADFVITGEGRIDQQTVYGKTPIGVAKAAKQYGVPVIAIAGSLGQGYEAVFEHGIDAAFSLVPRIMSLDEAMQQGDSLLEQAARNIAVVSSWNKST
What are the official names of this protein?
Glycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the glycerate kinase type-1 family.
Protein: COAD_STAA9
Sequence: MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_CANAL
Sequence: MVFETSKATSYLKDYPKKDGLSVKELIDSTNFGGLTYNDFLILPGLINFPSSAVSLETKLTKKITLKSPFVSSPMDTVTEENMAIHMALLGGIGIIHHNCTSEEQAEMVRKVKKYENGFINDPVVISPEVTVGEVKKMGEVLGFTSFPVTENGKVGGKLVGIITSRDIQFHEDNKSPVSEVMTKDLVVGKKGISLTDGNELLRSSKKGKLPIVDAEGNLVSLISRTDLQKNQDYPNASKSFHSKQLLCGAAIGTIDADRERLDKLVEAGLDVVVLDSSNGSSVFQLNMIKWIKEKYPELQVIAGNVVTREQAALLIEAGADALRIGMGSGSICITQEVMACGRPQGTAVYGVTEFANKFGVPCIADGGIGNIGHITKALALGASCVMMGGLLAGTAETPGDYFYRDGKRLKTYRGMGSIDAMQQTNTNANASTSRYFSEADKVLVAQGVSGSVVDKGSITKFVPYLYNGLQHSLQDIGIKSIDELRENVDNGEIRFEFRTASAQFEGGVHGLHSYEKRLHN
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_BURPS
Sequence: MKSSGSARATRRNAVSSSSAPAHAEPPARRAAKPARKLDGAAARPLAPTNAASAKPQGRTREDKDRPLFEDIRYLGRLLGDVVREQEGDAVFDVVETIRQTAVKFRREDDKAAAQTLEKMLRKLTPEQTVSVVRAFSYFSHLANIAEDRHHNRRRRIHALAGSAAQAGTVAYALDKLKQAGDASSKTIKQFFEGALIVPVLTAHPTEVQRKSILDAQHDIARLLAERDQPLTARELAHNEALLRARVTTLWQTRMLRDARLTVADEIENALSYYRATFLDELPALYADIEEALAEHGLRARVPAFFQMGSWIGGDRDGNPNVTAATLDEAISRQAAVIFEHYLEQVHKLGAELSVSNLLVGASDALKALAAASPDQSPHRVDEPYRRALIGVYTRLAASARVRLGEGTVPVRSAGRGAAPVRATPYADAEEFAADLRVLTDSLALHHGESLATPRLAPLMRAAEVFGFHLASIDLRQSSDIHEAVVAELLARGGVEADYAALPEADKLRVLLAALADPRPLRSPYLDYSDLAKSELGVLERAHAIRAQFGARAVRNYIISHTETVSDLVEVLLLQKETGLFEGTLGTPHANARNGLMVIPLFETIADLRNASDIMRAFFALPGVGELLAHQGHEQEVMLGYSDSNKDGGFLTSNWELYRAELALVDLFDERGIKLRLFHGRGGTVGRGGGPTYQAILSQPPGTVNGQIRLTEQGEVIASKFANPEIGRRNLETVVAATLEATLAPHSNAPKQLPAFEAAMQTLSDAAMASYRALVYETPGFTDYFFSSTPITEIAELNIGSRPASRKLQDPKNRKIEDLRAIPWGFSWGQCRLLLTGWYGFGSAVAAYLDGAPDAAERGKRVALLKKMNKTWPFFANLLSNMDMVLAKTDLAVASRYAQLVADKKLRKHVFERIVAEWHRTADALAEITGAHARLAANPLLARSIKNRFPYLDPLNHLQVELIKRHRAGDTNARLRRGIHLTINGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: YQGF_RHOP2
Sequence: MPALILPLIEAAGHWPARGSLLGLDLGTKTIGVAVSDPDRRLATGIETVARKAFTADAQRLLALAAGRNACGFVLGLPLNMDGSEGPRVQSTRAFARNFARLTELPIGLWDERLSTAAVERELIANDVSRAKRAKIIDEHAAIYILQGALDRLATLNRAD
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ALIF1
Sequence: MTKKLLIKTWGCQMNEYDSSKMADLLGAANGYELTEEPTEADVLLLNTCSIREKAQEKVFHQLGRWKNLKDKKPDLVIGVGGCVATQEGDHIRQRAPYVDVIFGPQTLHRLPEMIRQSQSNEKPVMDISFPEIEKFDNLPEPKAEGATAFVSIMEGCSKYCTYCVVPYTRGEEVSRPLDDVLFEIAQLAEQGVREVNLLGQNVNAYRGPMHDGDICTFAELLRMVASIDGIDRLRFTTSHPLEFGDDIIAVYEDTPELVSFLHLPVQSGSDRILTMMKRPHTAIEYKSIIRKLRKARPDIQISSDFIVGFPGETAKDFQDTMKLIKDVDFDMSFSFIFSARPGTPAADYPCDIPEQEKKDRLAELQQQVNSQAMRYSRLMLDTEQRVLVEGPSKKNLMELRARTENNRVVNFEGSADLIGQFVDVKITDVFANSLRGELVRTEKDMGLRVVMTPAEMMEKTRREDDLGVGTFTP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABP41_LILDA
Sequence: PAFQGVGQRLGTEIESSKDEAATAALKTVELDAVLGGRTPEEETFETRLYQFNGANSNLQERALEVLQYLKVMGDPTVTLETTPGKSAEEFLLDENRPKDVALLDDGRVVEEETMETRLYQFNGANSNLGAERSAEEMLLNENRPK
What is the function of this protein?
Ca(2+)-dependent actin filament-severing protein that is required for pollen tube growth.  Probably regulates the dynamics of the actin cytoskeleton.  It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed.
What are the official names of this protein?
Villin-like protein ABP41, Calcium-dependent actin-binding protein ABP41.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PO2F1_MOUSE
Sequence: MNNPSETNKSSMESEDASTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSSEESGDSQQSSQPSSQPPSVQSAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTSQPTTPTRTIAAASVQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSTASSPSALNSPGLGAEGLNRRRKKRTSIETNIRVALEKSFMENQKPTSEDITLIAEQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPASLVATTPSLVTSSTATTLTVNPVLPLTSAAVTNLSLTDQDLRRGCSWEVLRSLPDRVTTTAGTTDSTSNNNTATVISTAPPASSAVTSPSLSPSPSASASTSEASSASETNTTQTTSTPLPSPLGASQVMVTTPGLQTAAAALQGAAQLPANASLAAMAAAAGLSPGLMAPSQFAAGGALLSLSPGTLGSALSPALMSNSTLATIQALASSGSLPITSLDATGNLVFANAGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASTGNSAPTASLHASSTSTESIQSSLFTVASASGPASTTTAASKAQ
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins.  Modulates transcription transactivation by NR3C1, AR and PGR.
What are the official names of this protein?
POU domain, class 2, transcription factor 1, NF-A1, Octamer-binding protein 1, Oct-1, Octamer-binding transcription factor 1, OTF-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_MESFL
Sequence: MASKATKTTQSKYAIINNQLRNDLPDFTSGDTIKVDVKIKEGEKFRIQTFEGLVIKTQGSGITYSVVVRKLSNGVFVERTFPLHSPIIDKVTIVKRGRVRRARIYYIRKLSGKAARIKEILPTKADKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RS14Z_THENN
Sequence: MAKKAMIERWKKPKKYKVREYTRCHICGRPRAVYREFGLCRVCFRKLALEGKLPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: HIS7_METHJ
Sequence: MRTAEIKRKTKETDITVRFSLDGSGKGTIHTGIPFFDHMLDSFTRHSRFDLDIQAIGDLEKGPHHTIEDIGIVLGQVFTHALGEGRGIQRFASVIVPMDESKAEVALDVGGRPYLVFEGSFSGPVEGVIESWLVRHFFESFIQNAKVTAHMNVSGFSDHHKCEALFKAFGVALHSATKIVYDDGQVPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE5A_BOVIN
Sequence: MERAGPGSARPQQQWDQDSVEAWLDDHWDFTFSYFVRKGTREMVNAWFAERVHTIPVCKEGIKGHTESCSCPLQPSPRAESSVPGTPTRKISASEFDRPLRPIVIKDSEGTVSFLSDSDKKEQMPLTSPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLVCEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPRFNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKDKRFPWTNENMGNINQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEETTGKVKAFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCKWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQKRLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIMKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQEKTLINGESSQTKRN
What is the function of this protein?
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides.  This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:8530505).  Specifically regulates nitric-oxide-generated cGMP (By similarity).
What are the official names of this protein?
cGMP-specific 3',5'-cyclic phosphodiesterase, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.