PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_SYNPW
Sequence: MAAAAPASAGTKGVVRQVIGPVLDVEFPAGKLPKILNALRIEGTNTAGQPVALTAEVQQLLGDHRVRAVAMSGTDGLVRGMEALDTGAPISVPVGEATLGRIFNVLGEPVDEQGPVNASATAPIHRSAPKLTELETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKDSGVINAEDLSKSKVALCYGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFVDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGELQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPAVVGEEHYKTARAVQSTLQRYKELQDIIAILGLDELSEDDRRTVDRARKIEKFLSQPFFVAEIFTGMPGVYVKLEETIAGFNQILAGELDHLPEQAFYLVGNIDQVKAKAEKIAAEAK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PLSX_PECAS
Sequence: MTRLTLALDAMGGDFGPCVTVPAALQALASNPALNLLLVGDPAAITPLLAKVDSDLLSRLEVVPAESVIASDARPSQAIRASRGTSMRIALELIKDGRAQACVSAGNTGALMGLAKLLIKPLEGIERPALVSVLPHQQHGKTVVLDLGANVECDSTMLVQFAVMGSVMAEEVLELTNPRVALLNIGEEESKGLSTIREAAAQLKETPSINYIGYLEGNDLLTGKTDVMVCDGFVGNVTLKTVEGVVRMFLSLLKSPASGPEQKQKRSWWLKWLGRLLQKRLSKRFGHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAMQTVRRQLPERIAARLEAVLPKSD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ATP9M_NEUCR
Sequence: MIQVAKIIGTGLATTGLIGAGIGIGVVFGSLIIGVSRNPSLKSQLFAYAILGFAFSEATGLFALMMAFLLLYVA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity).
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS15_LYSSC
Sequence: MAITKERKNEIIAEYRTHESDTGSPEVQVAVLTAEINALNTHLRTHKKDFHSERGLLKMVGRRRHLLKYLRETDVQRYRELINRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DXR_PSEPK
Sequence: MGCDVSRPQRITVLGATGSIGLSTLDVIARHPDRYQAFALTGYSRIDELLALCVRHRPAFAVVPSTEAAVRLRASLAAAGCTTEVLEGEAGLCQVASAAEVDAVMAAIVGAAGLRPTLAAVEAGKKVLLANKEALVMSGALFMEAVRQKGAVLLPIDSEHNAIFQCMPGDYARGLSAVGVRRILLTASGGPFRETPVEALLDVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAVPSKVEVVVHPQSVIHSLVDYVDGSVLAQLGNPDMRTPIANALAWPERIDSGVAPLDLFAIARLDFQAPDEQRFPCLRLARQAAEAGNSAPAVLNAANEVAVQAFLERRIRFPEIAGMIEQVLDQEPVVPLPSLDAVFAADQRARELSREWLRRHGR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MAF5_ARATH
Sequence: MGRRRVEIKRIENKSSRQVTFCKRRNGLMEKARQLSILCGSSVALFIVSSTGKLYNSSSGDSMAKIISRFKIQQADDPETLDLEDKTQDYLSHKELLEIVQRKIEEAKGDNVSIESLISMEEQLKSALSVIRARKTELLMELVKNLQDKEKLLKEKNKVLASEVGKLKKILETGDERAVMSPENSSGHSPPETLPLLK
What is the function of this protein?
Transcription factor involved in the negative regulation of flowering time in short days, probably through the photoperiodic and vernalization pathways.  Prevents premature flowering, particularly in the cv.  Landsberg erecta background.  In non-inductive photoperiods (e. g.  short days), required for flowering through VIL2-mediated maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)-dependent H3K27me3.
What are the official names of this protein?
Protein MADS AFFECTING FLOWERING 5, MADS box protein FCL1, MADS-box protein AGAMOUS-LIKE 68.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIC_SHEON
Sequence: MSSLESSSESIAVNILGQTNRRVARAQAQAFIDTLKPLQHPNSQKLYLQGSRADLRVGMRQILQTDTRIGGRAAAPNVEKNPPIPVYDCAGPYSDPAAQINVRQGLAKLRLPWIIERQDTEVLDCTTSDFTQQRLKDDGLDHLRFEAGSSAIIRPRRALPGKRVSQLHYARQGIITPEMEYVAIRENMALADVQDEILNRRGQGESFGAVIGKPITPEFVRDEIARGRAIIPLNINHPEAEPMTIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEHLTWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLSHHQENFLYTHFREICELCVAYDVSLSLGDGMRPGSIADANDEAQFAELETLGELVNIAWEYDVQTIIEGPGHIPMQLIKENMDKQLIHCAEAPFYTLGPQITDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKQDVKQGLIAYKIAAHAADIAKGHPGAQIRDNALSKARFEFRWEDQYNLGLDPDTARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQDVRDYAASLEADAKAQSLAAETDGALAPLGSVQQVKSGHSELSHIDAELNYIAVKTQDELTAAMAQKSAEFAALGAKLYLPLDNANAANELAKHKDGAKLQSKTQVAKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: LSPA_PSET1
Sequence: MSKLAQKSGLVWLWLSLLLLVVDFASKTLVVSSMAYQESINLLPVFSITYVHNYGAAYSFLSDAGGWQRWFLSAIAIAISGLLVWWLKRLPATNKVLCAAYSLVLAGAIGNLYDRIAYGYVIDFIHVFYKNSHFPVFNVADCAICIGAALLLFDAFTGESPKEHKA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: POC1B_DANRE
Sequence: MASVMEDPTLERHFKGHKDVISCADFNPNNKQLATGSCDKSLMIWNLAPKARAFRFVGHTDVITGVNFAPSGSLVASSSRDQTVRLWTPSIKGESTVFKAHTASVRSVHFSRDGQRLVTASDDKSVKVWGVERKKFLYSLNRHTNWVRCARFSPDGRLIASCGDDRTVRLWDTSSHQCINIFTDYGGSATFVDFNSSGTCIASSGADNTIKIWDIRTNKLIQHYKVHNAGVNCFSFHPSGNYLISGSSDSTIKILDLLEGRLIYTLHGHKGPVLTVTFSRDGDLFASGGADSQVLMWKTNFDSLNYRELLSKHSKRVTPDPPPHLMDIYPRSHHRHHPQNGTVEINPVADTQSTDPQVVEVGRVVFSTTDARNYDGASSSRAQFTSGMDSGPFRTHTQAREEEDENQEERFAGGMTASPAERSGIPSSLTSTLENIVQQLDILTQTVAVLEERLTLTEDKLRTCLDNQVLLMQQNQQLDRSDEESEGPPL
What is the function of this protein?
Plays an important role in centriole assembly and/or stability and ciliogenesis.  Involved in early steps of centriole duplication, as well as in the later steps of centriole length control.
What are the official names of this protein?
POC1 centriolar protein homolog B, WD repeat domain 51B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat POC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: Y807_PSEAB
Sequence: MSFFHGVTVTNVDIGARTIALPASSVIGLCDVFTPGAQASAKPNVPVLLTSKKDAAAAFGIGSSIYLACEAIYNRAQAVIVAVGVEAAETPEAQASAVIGGVSAAGERTGLQALLDGKSRFNAQPRLLVAPGHSAQQAVATAMDGLAEKLRAIAILDGPNSTDEAAVAYAKNFGSKRLFMVDPGVQVWDSATNAARKAPASAYAAGLFAWTDAEYGFWSSPSNKEIKGITGTSRPVEFLDGDETCRANLLNNANIATIIRDDGYRLWGNRTLSSDSKWAFVTRVRTMDLVMDAILAGHKWAVDRGITKTYVKDVTEGLRAFMRDLKNQGAVINFEVYADPDLNSASQLAQGKVYWNIRFTDVPPAENPNFRVEVTDQWLTEVLDVA
What are the official names of this protein?
Putative prophage major tail sheath protein.
What is the protein family that this protein belongs to?
Belongs to the myoviridae tail sheath protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIN3_XENLA
Sequence: MSWNLFKGGPKKQIVPKTVERDFEREYGKLQQLEDQIKKLQKDMKKSIEADLAMSKSAVRISSDLLGNPLCEPDVDFLQMVTALDTAMKRMDAFNQEKVNQIQKTVMDPLKRYSSVFPSLNMAVKRREQALQDYKRLQTKVEKYEEKDKTGAMIAKLHQAREELRPVRDDFEAKNHQLLDEMPKFYNSRTDFFKPSFQSLIRAQVVYYTEMSRVFGDLAQQVDEVQLSDAEREQENEARLAELRSLSIVADD
What is the function of this protein?
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
What are the official names of this protein?
Bridging integrator 3 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AGT1_RAT
Sequence: MFRMLAKASVTLGSRAASWVRNMGSHQLLVPPPEALSKPLSIPKRLLLGPGPSNLAPRVLAAGSLRMIGHMQKEMFQIMDEIKQGIQYVFQTRNPLTLVVSGSGHCAMETALFNLLEPGDSFLVGTNGIWGIRAAEIAERIGARVHQMIKKPGEHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYQCLLLVDSVASLGGVPIYMDQQGIDILYSGSQKVLNAPPGISLISFNDKAKSKVYSRKTKPVSFYTDITYLSKLWGCEGKTRVIHHTLPVISLYCLRESLALISEQGLENSWRRHREATAHLHKCLRELGLKFFVKDPEIRLPTITTVTVPAGYNWRDIVSYVLDHFNIEISGGLGPSEDKVLRIGLLGYNATTENADRVAEALREALQHCPKNKL
What is the function of this protein?
Catalyzes the transamination between L-serine and pyruvate and weakly contributes to gluconeogenesis from the L-serine metabolism.
What are the official names of this protein?
Alanine--glyoxylate aminotransferase, AGT, Serine--pyruvate aminotransferase, mitochondrial, SPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
[Isoform Peroxisomal]: Peroxisome. SUBCELLULAR LOCATION: [Isoform Mitochondrial]: Mitochondrion matrix.
Protein: CYPC_YEAST
Sequence: MFKRSIIQQSRLFSNSASRLGKKVFFDPAVNGTKIGRIEFELYDNVVPKTAENFRALCTGEKGWGYKGVPFHRIIPDFMIQGGDTDLTNGFGGKSIYGSKFADENFVKKHDKAGLLSMANAGPNTNGSQFFITTVPCPWLDGKHVVFGEVTKGMDIVKAIESYGTASGKPRAEIVIEEAGEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  This isozyme is required for growth on lactate at high temperature.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase C, mitochondrial, PPIase C, Cyclophilin C, PPI-III, Rotamase C.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: INTE_ECOLI
Sequence: MAARPRKNNVSVPNLYPLYSRKVNKVYWRYKHPVTGKFHALGTNEAEAIAIATEANTRLAEQRTRQILAISDRIATSKGKAITTSTWLDRYQAIQDDRLKSGDIRLNTYKQKAKPVSLLRERAGMKLISAVDVRDIAQLLDEYIAAGRPRMAQVVRSVLIDVFKEAQHYGEVPPGYNPALATKQPRRKITRQRLSLEEWKKIFDIADATHRYMGNAMLLALVTGQRLGDISRMKFSDIWDDHLHVIQEKTGSKIAIPLSLRLNAINWSLRDVVARCRDYAVSAYLVHFFRSTSQAERGAQVKANTLTMNFSKARDLARIDWGEGSPATFHEQRSLSERLYKEQGLDTQKLLGHKTQQQTDRYHDDRGKGWSKVAL
What is the function of this protein?
Integrase from the cryptic lambdoid prophage e14.  Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Prophage integrase IntE, Int(Lambda), Prophage e14 integrase, Prophage lambda integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: RL5_DEHMC
Sequence: MLKVEERYTNAVPELQKFFNYGNIMQVPKLVKVVINTGVGEAVSNSKAMETAEADIVAIAGQHPVVTRAKRSVANFKLRAGMPIGLKVTLRGQRMYDFLNKLFFITLPRVRDFQGVPNTAFDERGNYTLGFKDHSVFPEIDFNKIEKPRGLEICIVTTANTPEEGKKLLELLGMPFSKD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: UVRC_PSEAB
Sequence: MSAVFDASAFLATCSNRPGVYRMFDADAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAGAIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVMFLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEGGNGDVDIVAAIVTPGGACVHLISVRGGRVLGSKNFFPQVAIEEEVGEVLLAFLGQYYLSHQERDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAEQALGARLANRQHVAARFEALAEALDLAEPPQRLECFDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVAGLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARRGKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQIYAVLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10AB_RAT
Sequence: MPTETERCIESLIAVFQKYSGKDGNSCHLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFLQTSQKRI
What is the function of this protein?
Facilitates the differentiation and the cornification of keratinocytes.
What are the official names of this protein?
Protein S100-A11, Calgizzarin, S100 calcium-binding protein A11.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LT_POVMC
Sequence: MDRVLSRADKERLLELLKLPRQLWGDFGRMQQAYKQQSLLLHPDKGGSHALMQELNSLWGTFKTEVYNLRMNLGGTGFQNAERGTEESGHSPLHDDYWSFSYGSKYFTREWNDFFRKWDPSYQSPPKTAESSEQPDLFCYEEPLLSPNPSPPTDTPAHPAGRRRNPCVAEPDDSISPDPPRTPVSRKRPRPAGATGGGGGGVHANGGSVFGHPTGGTSTPAHPPPYHSQGGSESMGGSDSSGFAEGSFRSDPRGESENESYSQSCSQSSFNATPPKKAREDPAPSDFPSSLTGYLSHAIYSNKTFPAFLVYSTKEKCKQLYDTIGKFRPEFKCLVHYEEGGMLFFLTMTKHRVSAVKNYCSKLCSVSFLMCKAVTKPMECYQVVTAAPFQLITENKPGLHQFEFTDEPEEQKAVDWIMVADFALENNLDDPLLIMGYYLDFAKEVPSCIKCSKEETRLQIHWKNHRKHAENADLFLNCKAQKTICQQAADGVLASRRLKLVECTRSQLLKERLQQSLLRLKELGSSDALLYLAGVAWYQCLLEDFPQTLFKMLKLLTENVPKRRNILFRGPVNSGKTGLAAALISLLGGKSLNINCPADKLAFELGVAQDQFVVCFEDVKGQIALNKQLQPGMGVANLDNLRDYLDGSVKVNLEKKHSNKRSQLFPPCVCTMNEYLLPQTVWARFHMVLDFTCKPHLAQALEKCEFLQRERIIQSGDTLALLLIWNFTSDVFDPDIQGLVKEVRDQFAAECSYSLFCDILCNVQEGDDPLKDICEYS
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: Y1327_ARATH
Sequence: MVVLSTLALVRAAYSLNSFVFEAEDIRFGSPWWFVVVGVACFLVLFAGIMSGLTLGLMSLGLVELEILQQSGSSAEKKQAAAILPVVKKQHQLLVTLLLCNAAAMEALPICLDKIFHPFVAVLLSVTFVLAFGEIIPQAICSRYGLAVGANFLWLVRILMIICYPIAYPIGKVLDAVIGHNDTLFRRAQLKALVSIHSQEAGKGGELTHEETMIISGALDLSQKTAEEAMTPIESTFSLDVNTKLDWETIGKILSRGHSRIPVYLGNPKNIIGLLLVKSLLTVRAETEAPVSSVSIRKIPRVPSDMPLYDILNEFQKGSSHMAAVVKVKDKDKKNNMQLLSNGETPKENMKFYQSSNLTAPLLKHESHDVVVDIDKVPKHVKNRGRNFQQNGTVTRDLPCLLEDNEDAEVIGIITLEDVFEELLQAEIVDETDVYIDVHKRVRVAAAAAAAVSSITRASPAEIQSKVGQTVKKLVGKEARGTKNYTTKITEPLLAESDR
What are the official names of this protein?
Putative DUF21 domain-containing protein At1g03270, CBS domain-containing protein CBSDUF4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM3_CHLP8
Sequence: MKKEIIIGTRSSPLALWQAEFTKAELSKRFPDMNITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLLAGEIDLAVHSLKDVPTGTPEGLVITSFTEREDTRDVIISKSGKGLMDLPQNAKMATSSLRRMSQLLSLRPDLEIMDIRGNLNTRFKKFDEGDFDAMMLAYAGVYRLEFSDRITEILPHETMLPAVGQGALGIETRTDDAETREIVRVLNDDNTEMCCRAERALLRHLQGGCQIPIGSFGSYIDGTLKLLAFVGSVDGKTGLRNEVTKAVKTPEEAEAVGIELAEILLSMGAEKILADIRKTC
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: HDFR_YERPN
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEHWQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GLMM_HELHP
Sequence: MKTKDTKAKLFGTDGVRGRAGEVITPSSVIALGTSAGIHFRQHSLTNKILVGKDTRRSGYMIENALVSALTSVGYDVIQIGPMPTPAVAFLTEDMRCDAGIMISASHNPYDDNGIKFFNHYGYKLAQEEEESIESYYYNPTSLQSALKSGLEIGSSKRIDDVVGRYIVHIKNSFPKNLTLRGLRIVCDCANGAAYRVAPIVLSELGADVIAINDEPNGYNINKQCGAMHPEGLAQEVMTYRADVGFALDGDADRLVVVDNKGNIVNGDKLIGALALYQKQIGKLENNAIVATLMSNLALEEFLKSHQIGLHRCNVGDKYVWDKMREHKLNFGGESSGHIIFSDYAKTGDGLVSALQVLALLIQSGKSSQDALNPFEIYPSELVNLKVSQKKPLEKINGLQEKLDSISASGNRYLVRYSGTENKLRILVEGKDYKLVSEQVKMLVDLCQKQLNV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: URE3_MARMS
Sequence: MELLPREKDKLLVFTAALLAERRLNRGLKLNYPEAMAFITMEIIEGARDGKTVAELMAYGKTLLSAEQVMDGVVELIHEVQVEATFPDGTKLVTVHNPIN
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_YERPA
Sequence: MRNSDLAPLYRSAIGFDRLFNLLESGQNQSNGGYPPYNVELVDENNYRIAIAVAGFAEQELEITTQDNLLIVRGSHANEPAQRTYLYQGIAERNFERKFQLAEHIKIKGANLVNGLLYIDLERLVPESLKPRRIEIK
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCH_OREMO
Sequence: MRQSRLSIIFAAALFFKCYALTVALPMAKAEDGSLEKDAFTSLLNDEATENSLGDAELSSMTKSRAPRVIVIAADANLWRDLRVLHNGLPLYKRRVDENNQVVEHKDVGQDLTIPILRRDTMRCMVGRVYRPCWEV
What is the function of this protein?
Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha.  Induces melanin concentration within the melanophores.  May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.
What are the official names of this protein?
Pro-MCH.
What is the protein family that this protein belongs to?
Belongs to the melanin-concentrating hormone family.
Protein: 2AAA_HUMAN
Sequence: MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA
What is the function of this protein?
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.  Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (PubMed:15525651).  Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (PubMed:16580887).  Together with RACK1 adapter, mediates dephosphorylation of AKT1 at 'Ser-473', preventing AKT1 activation and AKT-mTOR signaling pathway (By similarity).  Dephosphorylation of AKT1 is essential for regulatory T-cells (Treg) homeostasis and stability (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Lateral cell membrane. Cell projection, dendrite. Note=Centromeric localization requires the presence of BUB1.