PharMolix/UniProtQA huggingface dataset:
Protein: NLGN2_HUMAN
Sequence: MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV
What is the function of this protein?
Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members.  Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells.  Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors).  Functions by recruiting and clustering synaptic proteins.  Promotes clustering of postsynaptic GABRG2 and GPHN.  Promotes clustering of postsynaptic LHFPL4 (By similarity).  Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing.  Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency.  May promote the initial formation of synapses, but is not essential for this.  In vitro, triggers the de novo formation of presynaptic structures.  Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity).
What are the official names of this protein?
Neuroligin-2.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane. Presynaptic cell membrane. Note=Detected at postsynaptic membranes in brain. Detected at dendritic spines in cultured neurons. Colocalizes with GPHN and ARHGEF9 at neuronal cell membranes (By similarity). Localized at presynaptic membranes in retina. Colocalizes with GABRG2 at inhibitory synapses in the retina (By similarity).
Protein: GUF1_ZYGRC
Sequence: MLASQAIKRIFHRSWKPLVRFNHGKAPTAIESIKKRIEDIPIENYRNFSIVAHIDHGKSTLSDRLLELTGVIQSGGNKQVLDRLEVERERGITVKAQTCTMFYHDKRYGKDFLIHLVDTPGHVDFRGEVSRSYASCGGALLLVDASQGVQAQTVANFYLAYSMNLKLIPVINKIDLDHADIAQAEDQIENTFELPKEDTIRVSAKTGLNVKEDLLPAIIDRIPPPTGCLDKPFRALLVDSWYDSYVGVVLLVHIVDGTVRKGDKVSSAQTGKKYEIKEIGIMFPDRTPTGILSTGQVGYVVPGMKASKDAKIGDTLMHLGREQETEVLPGFEEPKPMVFVGAFPSDGEEFKALNDDVNRLVLNDRSVSLKRETSNALGQGWRLGFLGSLHASVFRERLENEYGSKLIITQPTVPYMIKYYDGHERLITNPDEFPDLAERRNKVQAIQEPYVEAIMTLPQEYLGNVIKLCDHNRGQQTEITYLNMTGQVMLKYDLPLGQLVEDFFGKLKSVSRGYASLDYEDIGYRDSDVVKLELLINGSSVDALAQVMHSSQVERVGRAWVKKFKEYIKAQLFEVVIQARANSKIIARETIKAKRKDVLQKLHASDISRRKKLLVKQKEGKKHLKSVGNVQINQDAYQAFLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CRCB_BEII9
Sequence: MRDSLLVFCGAGLGGLLRHGLNQVSLRLALFGFPWMTCFINISGSLAMGLLVGYLAGHGDSRFPQSLRLFLATGVLGGYTTFSTFSLENALLIERGAVGLAVLYSLVSVGLGLGGLFLGLTLTRSLS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_HELPJ
Sequence: MRILGIDPGSRKCGYAIISHASNKLSLITAGFINITTTRLQEQILDLIEALDCLLDRYEVNEVAIEDIFFGYNPKSVIKLAQFRGALSLKILERIGNFSEYTPLQVKKALTGNGKAAKEQVAFMVKRLLNITSEIKPLDISDAIAVAITHAQRLKPR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RIMM_PSEPW
Sequence: MNATPEKADDLIVVGKIFSVHGVRGEVKVYSFTDPIENLLDYPRWTLRHEGKVKQVELVSGRGSQKGLVVKLKGLDDRDEARLLSGFEICIPRSLLPNLAADEYYWYQLQGLKVINQDEQLFGKVDHLLETGANDVMVVKPCAGSLDDRERLLPYTAQCVLAIDLEAGVMRVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCS1_ARATH
Sequence: MVSNCLSLSLHLNLHPHKHNRHSLSSLRSRTKAKLYQHVSFTDSSHKSSYTSCVSTFDIQRKSSKHYELGKHSFSPILPGDNLVLSRSGVIRPRLSAMTGSEINDHGYDESQFDPSLTNDDLKPTTPSQRTFSWLDMSSLWIGLVVGVPTYYLAGSLVDLGMAWWQGIATVVTANLILLVPLVLTAQPGTLYGISFPVLARSSFGIRGAHIPTLLRALVGCGWYGIETWIGGEAIFLLLPGHIKKSALSHTLPWLGTSPLEFSCFIVFWLAQLCIVWRGMDGIRKLEKYSAPILISLTSCLLAWSYLKAGGFGHMLSLSSKLTSAQFWTLFFPSLTANISFWATLALNIPDFSRFAKSQTDQIIGQVGLPVFMGLFTFVGVAVTSSTSIIFGRVISNPIELLGQIGGLATTLLAIVGISLATLTTNIAANVVAPANALVNLNPKFFTFGRGAFLTAVLGIVFQPWRLLKSSESFVYTWLIGYSALLGPIGGIILVDYYLIKKMKLNIGDLYSLSPSGEYYFSKGYNVAAVVALVAGIIPVVPGFLHKISALSKISNGFVVVYDNALFFSFIIAGFVYWIIMSRLGRKQSSLSSSSHPLL
What is the function of this protein?
Nucleobase-proton symporter that facilitates the uptake of nucleobases in the cells.  Can transport adenine, guanine and uracil (PubMed:22616996, PubMed:22474184, PubMed:24621654).  Contributes to uracil import into plastids for plastidic uracil salvage which is essential for plant growth and development (PubMed:22474184).
What are the official names of this protein?
Purine-uracil permease NCS1, Nucleobase cation symporter 1, AtNCS1, Plastidic nucleobase transporter, Uracil/purine transport protein NCS1.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Plastid, chloroplast envelope. Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RL31_COXBR
Sequence: MKENIHPPYKQIKVTCSCGNTFMTGSTLDRELHLEICSACHPFYTGQQKMVDTAGRVERFRKKYAKRRAANASPEDEKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: DEF_TREPA
Sequence: MELKFLGEPCLTTVSEPVSEVDEQLRAFISGMFRVMRGAGGVGLAAPQVGRTVRVFVVDVEHHVRAFINPQITAASEEQSSYEEGCLSIPHIYERVLRPRRVSVQYLDENGKRCAVDADGILARVIQHEYDHLDGILFLDRIDEKRRDDALRRYAALRGTIR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ESR2_CALJA
Sequence: MDIKNSPSSLNSPSSYNFGQSILPLEHGPIYIPSSYVESHHEYPAMTFYSPAVMNYSIPSSVTNLEEGPGRQITSPNMLWSTPGHLSPLAVHHQLSHLYAEPQKSPWCEARSLEHTLPVSRETLKRKVSGNHCASPVTGPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQGNAEEQLHCAGKAKRSGGHVPRVRELLLSALSPEQLVLTLLEAEPPHVLISRPSVPFTEASMMMSLTKLADEELVHMISWAKKIPGFVELSLLDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPNLILDRDEGKCVEGILEVFDMLLATTSRFRELKLQHKEYLCVKAMVLLNSQYDPLVTATQDAESSQKLAHLLNAVTDALVWVIAKSGFSSQQQSVRLANLLMLLSHIRHASNKGMEHLLSMKCKNVVPVYDLLLEMMNAHVVRGCKSSITGSECSPAEDSKSTEGSQNPQSP
What is the function of this protein?
Nuclear hormone receptor.  Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSA_NITMS
Sequence: MSNSKLFSDAKKVIPSGVNSPVRYFEPYPFFTKKANGAYIWDVDNRKLIDFCNGYGALLLGHRRKEIINSVSKQLTKGTLYCTPTEGETELAKLIIGNFPSIDKVRLMNTGGEATMTAIRLARGFTKKKKIIKFEGCYHGAHDSVLVKAGSGSAHNGISVSDGGLDEVSKNTLVVQYNNIEDLQKTIQKNKDIAGVIVEPILANMGLILPEKNFLSDLRKITKENNIPLIFDEVVTGFRVAPGGAQEHFGIKPDITTMAKALSNGFAISAVGGKKEIMDLLSPGGKVYQASTFAGNPISVSAAIASIKTINKLKNKLYSKLERFNLLFSTALDDMATDMGIPHQINFTASMFQIFFTNKPVTNYETSKKANAKKFQKLFRTLLKKGIFIAPSQFEVVFLSDAHTENDLNKTLDAYHLALKSVKN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_CELJU
Sequence: MIKIRRGLDLPINGKPNQSIEDGPQVRQVALIGFDYQGMKPTMAVKVGDRVKLGQELFADKKIEGVIYTSPASGVVSAIHRGDQRVFHSIVIDVEGDDALAFNQYAAADLAGLSAEQVQQNLVQSGLWTAFRTRPYSKSPTPGSKPHSIFVQAIDTNPLAADPAVIIAAKADAFANGLTLLARLTEGKVFVCQAEAANLPKGQGANIAYESFAGVHPAGNPGTHIHYLDPVSASKTVWTIGYQDVIAIGELFTTGRLNVERVVALAGPQVDRPRLVRTRLGANLDQLTQGQLKAGENRVISGSVFGGRRSFGNLTFLGRFHTQVSVLLEGREREMLHYLRAGFNKFSVMGIFISKLFPSKTFDFTTSTNGSERAMVPVGSYEKVMPLDILPTQLLRSLIVGDTETAQKLGCLELDEEDLALCTFVCPGKYEYGPILRNNLTRIENEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: RL14_PELPB
Sequence: MIQKETNLVVADNSGAKKVRCIHVFGGTGRRYASLGDQIIVSVKAAVPGGIVKKKDVCRAVVVRCVKESRRKDGSYIRFDENAVVLLNAQGEPRGTRIFGPVARELRDRKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NADK_BIFLD
Sequence: MAKRNAVVVTHTRLRQTGTVVAEAVSQLRVAGFEVAIIDNTEAPDFGVQPPCVSDDTEIVVVLGGDGTILRAAELVHCTQVPILGVNMGHVGFLAEFESFQIDEAIRRVSTHDYSIDERMIAHVDVWLPGATKPIEDWALNDITLERADRGKMVELSIRVDDVEMNSFGADGVIVSTPTGSTAYAFSAGGPVMWPNVKALQLIPLAAHALFARPLIIGSGSTFTIDILDDSMSEGWICCDGRRQRALPQGTRVMVRESRDTLRLARLSGVPFTNRLVSKFDLPVVGWREHARNEASSQSLHHGHTFPAAAYAAGVAVAGDAGVAGTEPDKPGERDGKAGS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFB18_RAT
Sequence: MQSAMKLFFIFLIFVFSVSCGPSAPQMKTRDVLERTHKCFLVGGECKSECSSWEYEYVFCYTGPCCVMREYKRVEKFSNTPKYTT
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 18, BD-18, Defensin, beta 18.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRC_IDILO
Sequence: MTEGNQQKQFDSDSFLRHLTHQPGVYRMYDESGDVIYVGKAKDLRKRVSSYFREKVDRMKTQVLVKQIASMDVTVTNTEAEALILENSFIKKYRPRYNVLLRDDKSYPYIILTSHQHPKLGFHRGARRAKGDYFGPFPNGSAVRESLNLLQKLFPIRQCDDSYYRARTRPCLQYQLKRCLAPCVNVCTDDEYNEQVALAKQFLQGKNQQVIDELMNKMEQASTDLDFERAARFRDQIAALRKTQERNSVTGSQQELDVIGLARGNGMTTVQMLFIRDNHLQGSRSYFPKVPTDTPDDEVLRAFLLQFYLSDTAGRKIPREVVLPVDVQPDNVLAEVMSDALSQPVKLQSSVRGDKRQYQSLAQKNAVNALESRLNQQSTMNRRTQALQQVLEFGVPIQRMECFDISHTMGQQTVASCVVFDQNGPKKSDYRRYNITGITPGDDYAAMSKALAKRYDNAKEQGNIPDILFIDGGKGQLAQAENYFNDWGKEAPVLIGVAKGESRKPGLETLIMAGSHETIPLSKDASALHLIQHIRDESHRFAITGHRQKRAKVKKTSTLEQIDGVGAKRRQAILKNLGGLQEVKNASIDKLASVPGISRSLAEKIYYSFRDE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_POLNA
Sequence: MSLEGVFKEGFVTTSYDSVVNWAKTGSLWPMTFGLACCAVEMMHAGAARYDIDRFGMLFRPSPRQSDLMIVAGTLCNKMGPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQQKIRRTNTIARA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CNEP1_BOVIN
Sequence: MMRTQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLSQVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW
What is the function of this protein?
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2.  LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol.  May antagonize BMP signaling (By similarity).
What are the official names of this protein?
CTD nuclear envelope phosphatase 1, Serine/threonine-protein phosphatase dullard.
What is the protein family that this protein belongs to?
Belongs to the dullard family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein: WDR12_DROME
Sequence: MDVDNGEGQVQVHLKTKQEHYAVPDVPYAIDGTVTTVELNTFVNALLRQKDGSSDTDFDFLVFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKARGKWILSGCYDNTLNLWTNKGKHILTISGHTAPIKAVDWISLDEETGRFVSTSQDQTAMLWQWNVGSNSVECVSVCKGHERGVDSVSVSPDGLRFATGSWDTMLKVWSAELDDAVEGSSKRMKESGVRTPKITLQGHRESVSAVQWMDATTLLTGSWDHTLKVWDLSLEGIKTEISTNKSIFDASYSKLNRLILTASADKNLRLYDPRTNQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGAYDNQNKLWDCRSPKAPLYDLLGHGEKVLDIDWSNPKYIVSGGVDNTVRVFKSRKALAEEAETK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PSA6_YEAST
Sequence: MFRNNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-6, Macropain subunit PRE5, Multicatalytic endopeptidase complex subunit PRE5, Proteasome component PRE5, Proteinase YSCE subunit PRE5.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYE1_BRUO2
Sequence: MTVTVRFAPSPTGYIHIGNTRTALSNWLYASKNNGKFILRYDDTDVERSKDEYAQAIAVDLDWLGVRPDRVEYQSKRFDIYAKAVEKLKTAGLLYACYETADELERRRKLRLARRLPPVYGREALKLTDAEKAALEAEGRKPHWRFLLPNFESDPFATQRTEVHWDDLVRGPQTVDLASMSDPILVREDGTYLYTLPSVVDDIDMGVTHIIRGDDHVTNTGVQISIFKALGATPPVFGHHNLLTTISGEGLSKRTGALSVGSLREAGYEPMAVASLAILIGTSESVTAAPDMAALAEHFDLASISKSSAKFDPSELDALNRSLLHEMPFEKAKPRLEALGICGAKAESFWLAVRGNLDRFSDVSHWWQVVSGDLPEAPDLSGEDRDFVRHAFDLLPPEPWNGQTWKSWTEAVKSATGRKGKNLFMPLRLALTGQAHGPELADLLVLVGLERTKSRRP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_CAMJJ
Sequence: MKIYKLQTPVNAILENIAADKSISHRFAIFSLLTQEENKAQNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGISGFFVLSGDKYLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQKLKAFNFKSEISSAQVKTAMILSAFRADNVCTFSEISLSRNHSENMLKAMKAPIRVSNDDLSLEINPLKKPLKAQNIIIPNDPSSAFYFVLAAIILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALAKGKSSLINAKELRVKESDRIAVMVENLKLCGVEARELDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGARIDY
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIM_ELHVK
Sequence: MTIQVLFATEYDSANIVISLLCGVEVDHDLYPILYKRINYNNGASNNDGSRSGAINFDDRVNDEDSRLNAPVDDTIEFCLQTQSCEDSIRIRPVFYCHAHALNFETRYRTHEVLGSATLLQCLDESRTLTMYRRILSEIITEPSSASEKRNPAPTNLRHLVYFHRDVLVKYLTENFIMPTSPAWFISVFGSYEASLVLTMHYYLLERQYSTVQTTQHYAKCFTGDMGKPLVSCYSMKDFMIMIQSSAFLGKTAKFTHYCKLKNDRDLQELMAIDASINAFRQNVCLTEAEHVHFMYLAFGTALAKTKFLDYTLKTSLLSNNDDQTNNCNDYIVDNCAVDNHCQNDIDEIIIPRSSTNRTFAISEVSYDRSNSTSSSGVYSMDSCDESRGSEDSAMCSLYESRYLSHNLKKELLNIMELYFTPTSYLNIYVKVHKHESKSPLFEGYSIDTCSEKGTVFSGTSTSMADRLRKGNKMFEGLFEETDSEGVSSVLNIIASNRHAILPRCEDDDSCGKSTSGMPNRICKREIVFPGLTRPAPMYRTDGFNNMQICRYFSVVSKENWFSNSNLTDVLNMVPDEYVSDERLTESVWVPDVKVSSPRLSEQLYRSRHEMFNDRLPVYNFVGDVDLKVTGPVSKDWMFSFCRTLRRIILETFEHLFEKIDHGEHPVYFFKSGCEPENGSFCACSEKIGLRVITPFPRNTCILGGKTMKHLCEIINHILFLDKEMFSLVNVTVVDKNCFDYGIYSHGKSVRLPMMSKVDENLGFLQNRLLPLFIVPDSYRHGGRHKVFVRDQLNISNWLHHNASGTAYDPCKTISYVLSIDDVGRAQDVSFIDHKLNKLLKKEYVHIDTIIELFKSKYDISETRYFIEKIVWPQFLRTIKTNYHSAAGNQFNNVCFDDTSWPCVQLFKIHQGTRRNFSCIQHDHRDGRENVQFFLDFRPESATTIWTTLWSRCFSRKCKSNAKNVHVSHKLTIQQ
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.