PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_SHEB5
Sequence: MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQASLGEQQLNWVLQAEQLGTGHAVAQASPHIADSDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLGNPMGYGRIVRTPCEGQEQGKVVGIIEQKDATAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLERAYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEGAKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPC_MYCTU
Sequence: MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT
What is the function of this protein?
Involved in the lysine biosynthetic pathways.  It catalyzes the transfer of an amino group from L-glutamate to N-succinyl-2-l-amino-6-oxoheptanedioate (N-succinyl-2-l-amino-6-ketopimelate) in a PLP-dependent reaction, yielding as products N-succinyl-l-2,6-diaminoheptanedioate (N-succinyl-diaminopimelate) and 2-oxoglutarate (Probable).
What are the official names of this protein?
Probable N-succinyldiaminopimelate aminotransferase DapC, DAP-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSXC_CLOS1
Sequence: MMSMDEMRGNYDSNSYKSADHDCHKDCGRVIESQTLPLCEGTNITPTAVTTPVVAKIPVVLAEKEVQIDVEARMKLKEKFFEIKRIKKDVFLTQCELLPRAGVIENGVPITGKLFLSGFVRKNIEFATADCVKHDVVSGEIKHTTEKIPFTCVTEVTYITPPILGNRGIQQKTDLFCGRCDCECECEEERLGKLTCEEFLEDSITLVEKPFCELLGARIFEADIQRKPCYEHGEKVFDELLEKMVVHIRVKVLQLQQVAVNDTDAGTGSMCRK
What are the official names of this protein?
Exosporium protein C.
What are the subcellular locations of this protein?
Spore wall. Note=Localizes to the exosporium.
Protein: SPNR_SACSN
Sequence: MINLHQPILGTEELDAIAEVFASNWIGLGPRTRTFEAEFAHHLGVDPEQVVFLNSGTAALFLTVQVLDLGPGDDVVLPSISFVAAANAIASSGARPVFCDVDPRTLNPTLDDVARAITPATKAVLLLHYGGSPGEVTAIADFCREKGLMLIEDSACAVASSVHGTACGTFGDLATWSFDAMKILVTGDGGMFYAADPELAHRARRLAYHGLEQMSGFDSAKSSNRWWDIRVEDIGQRLIGNDMTAALGSVQLRKLPEFINRRREIATQYDRLLSDVPGVLLPPTLPDGHVSSHYFYWVQLAPEIRDQVAQQMLERGIYTSYRYPPLHKVPIYRADCKLPSAEDACRRTLLLPLHPSLDDAEVRTVADEFQKAVEHHISQRSPLRK
What is the function of this protein?
Involved in the biosynthesis of forosamine ((4-dimethylamino)-2,3,4,6-tetradeoxy-alpha-D-threo-hexopyranose), a highly deoxygenated sugar component of several bioactive natural products such as the insecticidal spinosyns A and D (PubMed:11358695, PubMed:18345667).  In the presence of pyridoxal 5'-phosphate (PLP) and alpha-ketoglutarate, catalyzes the C-4 transamination of dTDP-4-keto-2,3,6-trideoxy-alpha-D-glucose to yield dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-glucose (PubMed:18345667).  It can also use pyruvate, but less efficiently than alpha-ketoglutarate (PubMed:18345667).  Also able to catalyze the C-4 transamination of dTDP-4-keto-2,6-dideoxy-alpha-D-glucose to yield dTDP-4-amino-2,4,6-trideoxy-D-glucose (PubMed:18345667).
What are the official names of this protein?
dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase, dTDP-4-keto-2,3,6-trideoxy-D-glucose 4-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: Y644_THEKO
Sequence: MESEGRRVVHIGLPELTEEQIIEVGELAQRVVIKHVFDALNRSDVKDIEVTTRINRGETLDLELEVYLEVPVFVKVDVERLIDEAVEKAYAAVEKKLREIANEGQDKA
What are the official names of this protein?
Uncharacterized protein TK0644.
What is the protein family that this protein belongs to?
Belongs to the UPF0440 family.
Protein: COLI_ONCKE
Sequence: MVCAPWLLAVVVVCVCNPGVGGQCWDSSHCKDLPSEDKILECTHLFRSGLQDESPEPRSAAQQSTEESLSLGILLAALTSGERALDADPEPHSDKRHSYSMEHFRWGKPIGHKRRPIKVYASSLEGGDSSEGTFPLQARRQLGSWEDEMVGALGNQGAKAQTKVVPRTLTVTGLQDKKDGSYRMGHFRWGSPTAIKRYGGFMKPYTKQSHKPLITLLKHITLKNEQ
What is the function of this protein?
Endogenous opiate.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: RNJ2_STAEQ
Sequence: MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGVDIVIPDIQYVIENKERLKGIFLTHGHEHAIGAVSYVLEQIDAPVYGSKLTIALVKEAMKARNIKKKVRYYTVNHDSIMRFKNVNVSFFNTTHSIPDSLGVCIHTSYGSIVYTGEFKFDQSLHGHYAPDLKRMAEIGDEGVFALISDSTEAEKPGYNTPENIIEHHMYDAFAKVKGRLIVSCYASNFVRIQQVLNIASQLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPINEVENYPKNEVIIIATGMQGEPVEALSQMARKKHKIMNIEEGDSIFLAITASANMEVIIADTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMLNIMKPEYFVPVQGEFKMQIAHAKLAAETGVAPEKIFLVEKGDVISYNGKDMILNEKVQSGNILIDGIGVGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEELLKEAEEKVRKIVEEGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 2, RNase J2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRD1_CANGA
Sequence: MSRVIVKGLPIYLTEPELQKHFNKRLITTHATSNVDGLITDLRILKNREGKSRRFAFIGYKNEQDALDAVNYFDGSFIYTSKIEVDMAKSFADPRVPKSMKEKKREALKRLREKEEKLLEEKNKKLKVQDTKSKINIDAEIEKDKQLKEFIETMKPSAQTSSWDKITETAEPESGLAEEQELDDEESSNVNPLLKHALSMKKGDENDSDDEYMSFNNADSKAGSDESNEEEKMISLSELPVQNEESSAEPKEDDGLAKNEEISDMDWIKQRRVRIRENGEKVGEEFATNVQDKESEENSQATPAEELQEEIPDEEQAIAKIQKTGRLFLRNILYSSTEDDFKKLFSPYGELKEVHVAVDTRTGNSKGFAYVLFAKPEEAVQAYIELDKQIFQGRLLHILAADEMKDHRLDEFDLKNMPLKKQRELKKKAAASKATFSWNSLYMNQDAVLGSVAAKLGVQKADLIDPENSNSAVKQALAEAHVIGDVRKYFETKGVDLTKFSNLKSPSQRDDRVILVKNFPFGTTREELGELFVPFGKLERLLMPPAGTIAIVQFRDIASGRSAFSKLAFKRFKGTVIYLEKGPKDCFTKAASNEDAMEHDEEKSAKEAGPSSADLLESVSSKKTEDKEDEDEQVVDGPTVSIFIKNLNFKTTSQQLTDRFKVFSGFVVAQVKTKPDPKQKNKVLSMGFGFVEFRTKEQATAVISAMDGTVIDGHKIQLKLSHRQGNAGSQEKKKAKNGKIIVKNLPFEATRKDVFELFNSFGQLKSVRVPKKFDKSARGFAFVEFVLPKEAENAMDQLQGVHLLGRRLVMQPAEQEAANAEEELERMTKKVRKQAAVSEIAAMTRNAGKRKLDMEDEEEEF
What is the function of this protein?
Involved in pre-rRNA processing.
What are the official names of this protein?
Multiple RNA-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GG6L4_HUMAN
Sequence: MWPQPRFPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGANRKKKINGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEDRLHEQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERQQEEQERLLERERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLDEVEELLEQERLRQQDERLWQQETLQELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCGQAGWTPQEHPGLSGEAVGTGEAAGGAGEAACHSFRAAENRELNITII
What are the official names of this protein?
Golgin subfamily A member 6-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the GOLGA6 family.
Protein: CERU_MOUSE
Sequence: MKFLLLSTFIFLYSSLALARDKHYFIGITEAVWDYASGTEEKKLISVDTEQSNFYLQNGPDRIGRKYKKALYFEYTDGTFSKTIDKPAWLGFLGPVIKAEVEDKVYVHLKNLASRIYTFHAHGVTYTKEYEGAVYPDNTTDFQRADDKVLPGQQYVYVLHANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLYKEKEKNIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAADRVKWYLFGMGNEVDVHSAFFHGQALTSRNYQTDIINLFPATLIDAYMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPEDNIQDRHVRHYYIAAEEVIWNYAPSGTDIFTGENLTALESDSRVFFEQGATRIGGSYKKMAYREYTDGSFTNRKQRGPDEEHLGILGPVIWAEVGDTIKVTFHNKGQHPLSIQPMGVSFTAENEGTYYGPPGRSSQQAASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDPTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFPTVFDENESLLLDDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMNPDTKGTFDVECLTTDHYTGGMKQKYTVNQCQRQFEDFTVYLGERTYYVAAVEVEWDYSPSRAWEKELHHLQEQNVSNVFLDKEEFFIGSKYKKVVYRQFTDSSFREQVKRRAEDEHLGILGPPIHANVGDKVKVVFKNMATRPYSIHAHGVKTESSTVVPTLPGEVRTYTWQIPERSGAGREDSACIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFSPKKKMEFFLLFLVFDENESWYLDDNIKTYSEHPEKVNKDNEEFLESNKMHAINGKMFGNLQGLTMHVKDEVNWYVMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDLFPGTYQTLEMFPQTPGTWLLHCHVTDHVHAGMATTYTVLPVEQETKSG
What is the function of this protein?
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein.  It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species.  It is involved in iron transport across the cell membrane.  Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1.  May also play a role in fetal lung development or pulmonary antioxidant defense (By similarity).
What are the official names of this protein?
Ceruloplasmin, Ferroxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted. Note=Colocalizes with GCP1 in secretory intracellular compartments.
Protein: ATAT_PHYIT
Sequence: MRVEVVRAPGPLNRPALAEAIDTLGKKSATVRPSSATHRATAQTLSHEITSTDLFATSTATEQQQTLLLAINDDDGAVMGFLKTGVKHLFYLNPRGEYTEIDPICVLDFYVDEVWQRRGVGLQLFQRLLQEENTTPAQLAYDRPSPKLFAFLKKHVGLTEYFPQPNRFVVFDAYFQSRE
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: PGK_CHESB
Sequence: MAGFKTLDDLKDVAGKRVLLRVDLNVPVKDGEVTDTTRIERVAPTITELSDKGAKVILLAHFGRPKGKPDAEASLQPIAHAVEAVLDRRVHFASSCIGEPAKKAVDEMTGGDILLLENTRFHAGEEKNDPEFTKALAANGDIYVNDAFSAAHRAHASTEGLAHLLPAYAGRTIQAELEALQRGLGDPKRPVVAIVGGAKVSTKIDLLTNLVKKVDCLVIGGGMANTFLAARGTSVGKSLCEHDLRETAKQIMIDAAEAGCAIILPVDAVVARKFEAGAETETVDIDAVPEDAMILDVGPKSVEKVKEWLDRADTLVWNGPLGAFELSPFDKATMEVAKYAARRTRESLLVSVAGGGDTVAALNQADVSDDFSYVSTAGGAFLEWMEGKDLPGVAALQK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP4CB_MOUSE
Sequence: MSASALSSIRFPGSISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKILKDQDLQDILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKAHGSYRFLAPWIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAHDHTDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFAPGSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPRIVLKSKNGIHLHLKKLQ
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids and their oxygenated derivatives (oxylipins) (PubMed:17112342).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:17112342).  Catalyzes predominantly the oxidation of the terminal carbon (omega-oxidation) of saturated and unsaturated fatty acids (PubMed:17112342).  May act as a major omega-hydroxylase for dodecanoic (lauric) acid in kidney (PubMed:17112342).  Participates in omega-hydroxylation of (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) to 20-hydroxyeicosatetraenoic acid (20-HETE), a signaling molecule acting both as vasoconstrictive and natriuretic with overall effect on arterial blood pressure (PubMed:17112342).  Acts as an omega-hydroxylase and epoxidase toward (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoc acid (EPA).  Catalyzes the epoxidation of the last double bond of EPA with no preferred stereoselectivity, producing both (R,S) and (S,R) stereoisomers (PubMed:17112342).  Can also catalyze the omega-1 and omega-2 oxidation of fatty acids with lower efficiency (PubMed:17112342).
What are the official names of this protein?
Cytochrome P450 4A12B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MRAY_XANC8
Sequence: MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLILLTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITFYIPMFKAIALPLAGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGELIIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTVAVIVRQELVLVIMGGVFVIETLSVMIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DZIP3_MOUSE
Sequence: MDSLAEEFFVSGNPDVEEQTKEETEIIAEKPVTQLDKQKMDISADPEPVNALLEIKKVLNPISALPKGVFPNIEKFIQEDFSFQTMQREVTTHSQTGEEIVPALTLHFLITQLEMALRNIQASNYTAQQINVGYYLTLLFLYGVALTERAKKEDCIEAENKFLVMKMVIQESEICENFMCLVYFGRGLLRCAQKRYNGALLEFYKSLQEIGDTDDNWFEVDPTDDEDLPTTFKDSLNNFIKTTESNIMKETICSYLDCERSCEADILKNTNYKGFFQLMCSKSCCIYFHKICWKKFKNLKYPGESDQSFSGQKCLKEGCPGDMVRMLQCDVPGIVKILFEVVRKDEYITIENLGASYKNLMSLELTDTDIRPKFNLKPNTKDEVPIFKLDYNYFYHLLHIIIISGTDMVRQIFDEAMPPTLLKKELLIHKNVLEPYYNHLWTNHPLGGSWHLLYPPNKELPQSKQFDLCLLLALIKHLNVFPAPRKGWDMEPPSSDLSKSADILRLCKYRDILLSEILMNGLTELQFNSIWKKVSDILLRLGMKQDDLDKVKENPIENISLDYHQLSIYLGIPVPEIIQRMLSCYQQGITLQSITGSQRLDVEEFQNDEEDLSPPVMEYNIDVKSNTEIQLAEINKDVASIPSESSTESVKDLQEVKSKTKKKKRTKSNKKDKDSEDEQVSYMVEKDDQLETEQVDVNTLSTYMKTDTSDAQEDSAAEDKFCSLDELHILDMVEQGSSGKESTDFKETEKERLAHQHQLYKLQYECEDYKRQLKTVTFRWQENQMLIKKKEKIIVSLNQQVAFGINKMSKLQRQIHAKDDEIKNLKDQLSLKRSQWEMEKHNLESTVKTYLNKLNAETSRALTAEVYFLQCRRDFGLLHLEQTEKECLNQLARVTHMAASNLESLQLKAAVDSWNAIVADVRNKIAFLRTQYNEQINKVKQGFALSTLPPVQLPPPPPSPEILIQQFLGRPLVKESFFRPILTVPQMPAVCPGVISAAVQPRPPLMPGITWAMPTPIGDTVSPSASLCSEPLMINWERITDRLKTAFPQQTRKELTDFLQQLKDSHGKSVSRLTFDEIVYKISQMIEPKKSESEEKSAQDGNNASPSHTASQPNAPQDPKSAQGSATWEGDKDMDNEEEEEEPCVICHENLSPENLSVLPCAHKFHSQCIRPWLMQQGTCPTCRLHVLQPEEFPGHPNGQLPKI
What is the function of this protein?
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Able to specifically bind RNA.
What are the official names of this protein?
E3 ubiquitin-protein ligase DZIP3, DAZ-interacting protein 3 homolog, RING-type E3 ubiquitin transferase DZIP3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_BORPE
Sequence: MESIEQRVKKIVAEQLGVNEAEIKNESSFLDDLGADSLDMVELVMALEDEFETEIPDEEAEKITTVQQAIDYINSHGKQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUB5_TRIVC
Sequence: MTGFFTILSFSLAALSVTNAAQILSVPKGAEVVPNGYIVVMKDDTSQQDFSSHRVWISSIHHNMTRRGLDGAGVKQTYDFDHLRGYSGIFDEDTIKDISNDPKVAFVEPDAIISQHVVVQQRKAPWGLSRLSNRRGGRNYVFDSSAGSGVWAYVVDSGVDVRHAEFQGRAVWGSNLVDNKNSDGTGHGTHVAGTIAGKTYGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGGTYSAGLNHATAQAIKAGMFVSVSAGNDNINSNGNSPASERSVCTIAASTENDGKASFSNWGPAVDLYAPGHNILSARPGGGSQTMSGTSMAAPHAAGVAAYLIAKEGIPGNRACLRLKQLSQPTIRNPGPDTTSRLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR2_HALH5
Sequence: MNVLVIGSGGREHTIAWKFAQSEKVERVYVAPGNDGMSDVATCVAISEQDHDQLVAFAKENKIGLTFVGPEVPLLAGIVDRFQEEGLRVFGPSKRAAEIEGSKSYAKQVMKTYNIPTGSYEVFTSFDEAKAYVEAEGVPIVIKADGLAAGKGVVVALTNEEAIAALDDMLNQDKFGGAGARVVIEEYLEGEELSLMAFVHGETVIPMVGAQDHKRAFDGDQGPNTGGMGAYSPVPQFSDVQLKQAVNEILIPTARALMQEERSFTGILYAGLMMTADGPKVIEFNARFGDPETQVVLPRLKSDLVNVIESLLDGQEPELEWDEQAVLGVVLATKGYPGSYEKGYTISGLEQLEDDTLVFHAGTKREEEELVTNGGRVLLVAKQASTLREAQAAVYEELNKVKSDGLFYRKDIGSKAIAERAVSSQTEQ
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: SYY_SYNAS
Sequence: MILKNVYDVFMERGFIEQVTDENAVRKALEAPLACYIGFDPTARSLHIGSLVPIMALIHLQRHGHTSIALVGGGTALIGDPSGKTEMRQILTREKIELNATCMRRQFARYLSFEDKKAMMINNADWLTKLNYISFLRDIGRHFSVNKMLAAESYKMRLEKGLNFIEFNYMLLQAYDFLYLFQNHNCVMQMGGNDQWGNMLAGVDLIRRVEGKVAHSMTFPLLTTATGQKMGKTEKGAVWLDRELTSPYEYYQYWINTGDIDVGKFLALFTFLPMEEIHQVKSLSDKELNMAKAILAFEATKITHGEDAALAAWNASAVAFGVKLIDTSLMPSSTIPRGQLSQDASAIPFIKKSWNELAKGIPAYEIMHECGLCSSKSEARRLIAQGGGYVNENPIFAFDELITTEHLDRSGQIKLRKGKKKYMIIKVE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUBR3_RHOSQ
Sequence: MSSYRCPVCEYVYDESKGAPREGFPAGTPWDAVPDDWCCPDCGVREKLDFEPMPATAGSES
What is the function of this protein?
Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
What are the official names of this protein?
Rubredoxin 3.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: TALDO_RAT
Sequence: MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRIIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDSSKLAPTLSVKAAQTSDLEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK
What is the function of this protein?
Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway.  Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. Actively transported into the nucleus in an importin alpha/beta-dependent manner. Exported into the cytoplasm by CRM1.
Protein: MIS19_SCHPO
Sequence: MDLMPLEKARAIEIAFDNVFHNTKIPDNLQQFDAILKRLERRRFIPTENQKPRVYETELLVLRFREFGVKDNHNHPINLHSLRSKSLIRAQGKKLDLHNRVFLRRNVRAVKM
What is the function of this protein?
Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:24774534, PubMed:24789708, PubMed:25375240).  Links mis16 and mis18 to recruit CENP-A through interacting with non-sense-mediated mRNA decay (NMD) factors and the SWI/SNF complex (PubMed:24774534).  Links also mis18 with the CCAN/mis6/ctf19 complex to promote CENP-A assembly (PubMed:24789708).
What are the official names of this protein?
CENP-A recruiting complex protein mis19, Eighteen-interacting centromere protein 1, Kinetochore protein mis19.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes at the centromeres during interphase, but not in mitosis (PubMed:24774534, PubMed:25375240).
Protein: HPCH_SALNS
Sequence: MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEALAARFGVEKKLSGASGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: HEM1_BACSU
Sequence: MHILVVGVDYKSAPIEIREKVSFQPNELAEAMVQLKEEKSILENIIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLSKEELSPFLTFYESDAAVEHLFRVACGLDSMVIGETQILGQVRDSFKTAQQEKTIGTIFNELFKQAVTVGKRTHAETDIGSNAVSVSYAAVELAKKIFGNLSSKHILILGAGKMGELAAENLHGQGIGKVTVINRTYLKAKELADRFSGEARSLNQLESALAEADILISSTGASEFVVSKEMMENANKLRKGRPLFMVDIAVPRDLDPALNDLEGVFLYDIDDLEGIVEANMKERRETAEKVELLIEETIVEFKQWMNTLGVVPVISALREKALAIQSETMDSIERKLPHLSTREKKLLNKHTKSIINQMLRDPILKVKELAADADSEEKLALFMQIFDIEEAAGRQMMKTVESSQKVHSFKKAESKAGFSPLVSE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.