PharMolix/UniProtQA huggingface dataset:
Protein: MTNA_TRIAD
Sequence: MTEQQSLEAIRYDHDHGQLKILNQLLLPSEYVYENVEGIEDGWQAIRQMKVRGAPAIAIVGMLSLAVELRSKSFTEMNEFDKFIRDSLEHLKTARPTAVNIFLACDLITKLIDNLIILGDEAVGVAKIEVIRHIEEMLHKDVESNKRIGSYGAEAILAKVPSKEKINVLTHCNTGSLATAGYGTALGVIRSLYGRDSIDRVFCTETRPYNQGSRLTAFELVHDGIPATLITDSMASLVMKKKDISAVVVGADRVLGNGDTANKIGTYQLAITAKYHKIPFYIAAPTTTIVLDDSKDIVIEERSHKEVTEIQGIPIAPSGINVYNPAFDVTPAELITGIITEVGVFSPSEMKSKLQTILNS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GRIA2_HUMAN
Sequence: MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
What is the function of this protein?
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system (PubMed:31300657).  It plays an important role in excitatory synaptic transmission.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.  Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
What are the official names of this protein?
Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Postsynaptic density membrane; Multi-pass membrane protein. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression (By similarity). Displays a somatodendritic localization and is excluded from axons in neurons (By similarity).
Protein: Y578_BACC3
Sequence: MGRKWNNIKDKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALRVVLERAKTYNVPRTIIDRAVEKAKGGSEENYDELRYEGFGPNGAMVIVDTLTNNVNRTAADVRAAFSKNSGNMGVNGSVAYMFDATAVIGLEGKTSDEVLEILMEADVDARDILEEEDAVIVYAEPDQFHAVQSALKDAGVEEFTVAELTMLAQNDVTLPEDAQAQFEKMVDALEDLEDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BCA_0578.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_PSEF5
Sequence: MSSGRIVQIIGAVIDVEFPRDSVPSIYDALKVQGAETTLEVQQQLGDGVVRTIAMGSTEGLKRGLDVNNTGAAISVPVGKATLGRIMDVLGNPIDEAGPIGEEERWGIHRPAPSFAEQAGGNDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGNDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKQGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPNVIGNEHYETARGVQYVLQRYKELKDIIAILGMDELSETDKQLVSRARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIAGFKGILNGDYDHLPEQAFYMVGGIDEAIEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARYB_MANSE
Sequence: MKTVIILAGLVALALGSEVPVKHSFKVKDVDAAFVERQKKVLDLFQDVDQVNPNDEYYKIGKEYNIEANIDNYSNKKAVEEFLQLYRTGFLPKYYEFSPFYDRLRDEAIGVFHLFYYAKDFDTFYKSAAWARVYLNEGQFLYAYYIAVIQRKDTQGFVVPAPYEVYPQFFANLNTMLKVYRTKMQDGVVSADLAAQHGIVKEKNYYVYYANYSNSLVYNNEEQRLSYFTEDIGLNSYYYYFHSHLPFWWNSERYGALKSRRGEIYYYFYQQLMARYYFERLSNGLGDIPEFSWYSPVKSGYYPLMSSYYYPFAQRPNYWNVHSEENYEKVRFLDTYEMSFLQFLQNGHFKAFDQKIDFHDFKAINFVGNYWQDNADLYGEEVTKDYQRSYEIIARQVLGAAPKPFDKYTFMPSALDFYQTSLRDPMFYQLYNRILKYIYEYKQYLQPYSSEKLAFKGVKVVDVVVDKLVTFFEYYDFDASNSVFWSKEEVKSSYPHDFKIRQPRLNHKPFSVSIDIKSEAAVDAVVKIFMAPKYDDNGFPLKLENNWNKFFELDWFTYKFVAGDNKIVRNSNDFLIFKDDSVPMTELYKLLEQNKVPHDMSEDYGYLPKRLMLPRGTEGGFPFQFFVFVYPFNADSKDLAPFEAFIQDNKPLGYPFDRPVVDAYFKQHNMFFKDVFVYHDGEYFPYKFNVPSHVMHSNVVPKH
What is the function of this protein?
Arylphorin is a larval storage protein (LSP) which may serve as a storage protein used primarily as a source of aromatic amino acids for protein synthesis during metamorphosis.  It is a constituent of the sclerotizing system of the cuticle, and serves as a carrier for ecdysteroid hormone.
What are the official names of this protein?
Arylphorin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the hemocyanin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ABCA5_RAT
Sequence: MATAIRDVGVWRQTRTLLLKNYLVKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVSDIELSPMDKSILSNLILGYTPVTNTTSSVMQRVSTDHLPDVLVTEEYASEKELLASSLSKPSNFVGVVFKDVMSYELRFFPDMVPVSSVYMDSRAGCSKSCDAAQYWSSGFTALQASIDAAIIQLKTNVSLWRELESTKAVIMGEAAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKRLKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASSLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVLVESFPRSLVWLFSPLCQCAFLIGIAQVMHLEDFNEGALFSSLTEGPYPLIITLTMLALDSVFYALLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKNKRNYKELSEGNINGNISLNEIVEPVSSEFIGKEAIRISGIQKAYRKKNETVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDMNFDVLTVEENLSILASVKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAAALLQQNDQQIVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPREEETDSKSFDEMEQSLLILSETKASLVSTMSLWKQQVSTIAKFHFLSLKRESKSVRSVLLLLLIFFAVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSTDSDINDLIDFFTQQNIIVAMFNDSDYVSAAPHSAALNVVQSEKDYVFTAVFNSTMVYSLPVMMNIISNYYLYHLNVTDTIQIWSTPFIQEITDIVFKVELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFVVLTLMLGSLFAFHHGLYFYPVKFLAVVFCLIAYVPSVILFTYIASFTFKKILNTKEFWSFIYSVTALACVAVTEITFFLGYGVTAVFHYTFCIAIPIYPLLGCLISFIKGSWKNIPKTENAYNPWDRLLVAVIMPYLQCVLWIFLLQHYEKKHGGRSIRKDPLFRALSQKAKHKKFPEPPINEDEDEDVKAERLKVKELMGCQCCEEKPAIMVYNLHKEYDDKKDFLHSRKTTKVATKYVSFCVKKGEILGLLGPNGAGKSTIINILVGDVEPTSGKIFLGDYGSHSNEDDESTKCMGYCPQTNPLWPDITLQEHFEIYGAVKGMSSGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEIDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFAKLEEAKHTFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERRQEDRVVF
What is the function of this protein?
Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport.  May play a role in the processing of autolysosomes.
What are the official names of this protein?
Cholesterol transporter ABCA5, ATP-binding cassette sub-family A member 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane. Note=Localized at cell membrane under high cholesterol levels.
Protein: UBIM_MUSSI
Sequence: MQLFVRAQELHTLEVTGQETVAQIKDHVASLEGIAPEDQVVLLAGSPLEDEATLGQCGVEALTTLEVAGRMLGG
What are the official names of this protein?
Ubiquitin-like protein FUBI.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
Protein: HV348_HUMAN
Sequence: MELGLCWVFLVAILEGVQCEVQLVESGGGLVQPGGSLRLSCAASGFTFSSYEMNWVRQAPGKGLEWVSYISSSGSTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-48, Ig heavy chain V-III region WEA.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: MOTI_SHEEP
Sequence: MLSRKATAILLVVHAAAMLASQTEGFVPIFTYGEVQRMQEKERYKGQKKSLSVQQRSEEVGPVDPAEPREEKQEVIKLTAPVEIGMRMNSRQLEKYQATLEGLLRKALPSSRNAQ
What is the function of this protein?
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
What are the official names of this protein?
Promotilin.
What is the protein family that this protein belongs to?
Belongs to the motilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBB_ORYSI
Sequence: MASVAELKEKHAAATASVNSLRERLRQRRQMLLDTDVERYSRTQGRTPVSFNPTDLVCCRTLQGHSGKVYSLDWTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMTCAFAPNGQSVACGGLDSACSIFNLNSQADRDGNIPVSRILTGHKGYVSSCQYVPDQETRLITSSGDQTCVLWDVTTGQRISIFGGEFPSGHTADVLSLSINSSISNMFVSGSCDATVRLWDIRIASRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDVRTGHQLQVYSREPDRNDNELPTVTSIAFSISGRLLFAGYSNGDCYVWDTLLAEVVLNLGNLQNSHEGRISCLGLSSDGSALCTGSWDKNLKIWAFSGHRKIV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta, WD40 repeat-containing protein 80, OsWD40-80.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: AOP3V_ARATH
Sequence: MGSCSPQLPLICLSDQTLKPGSSKWVKVRSDVRKALEDYGCFEAKIDQVSMELQGSVLKAMQELFALPTEAKQRNVCPKPFAGYFSHNGLSESFGIKDANILEKAHEFTQQLWPEGNKSIKMIQLYAEKLAELDMMVRRLILESYGIEYFIDEHLNSTYYRMRLMKYIARPDNDITAAVGANVDNGANDNADGDANVNDDGASIGVKVNVDVGDDVNDNDSVNIGVGVDINVETNVNGHLDAEANGDATAWVVGAVSGNASVGAKEANVDAELGLPSHTDKSLSGIIYQHQIDGLEVKTKEGKWIRVKPAPNTVIFIAGDALCALMNGRIPSPYHRVRVTEKKKTRYAAALFSNPKEGYIIDSPKELVDEKHPRAFKPFDFVDLFNFYHTEAGRRAPSTLQAFCGVSAGK
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis.  Catalyzes the conversion of methylsulfinylalkyl glucosinolates to hydroxyalkyl glucosinolates.
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase AOP3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: IOLD_CLOP1
Sequence: MRMTTGQALVKFLDNQYVSFDGKEEKFVDGIFTIFGHGIVVGLGEALYENPGELKVYQGRNEQGMAHVSTAFAKQNNRRKIIACSSSVGPGAANMVTAAATATVNNIPLLLLPGDSFATRQPDPVLQQIEQSYNLGITTNDAFKPVCKYWDRINRPEQLMSAMINAMRVLTDPAETGAVCIALPQDVQGEAYDFPEYFFKKRVHRITRPLAVQEEFEEALDIIMNKKKPIIICGGGVRYSEAGEALVDFAEEFNIPICETQAGKSAIKSSHPLNLGGIGVTGNLAANMIAKDADLVIGVGTRFSDFTTSSKSLFKNPEVDFITVNVSKFHGEKMDAHKIIGDAKVCIEELQAMLEANNYESSYEDEIVNAKKAWKEEMKRLTNIKYDENFEALIKPKREGCIEEFSVLTGGLITQTAALGVIRETIDDDAIVVGAAGSLPGDLQRMWETDVRDSYHMEYGYSCMGYEIAATLGAKLAEPEREVYSMVGDGSYLMLHSEMVTAMQEQKKINILLFDNCGFGCINNLQMSNGIGSLATEFRYRDENGKLEGGLIPIDFAKVASGYGLKTYSVKTLAQLKEALEDAKKQKVSTLIDIKVLPKTMTDGYDAWWHVGIAGESKIDGVNKAFENKEKNLKAARRY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: MURI_BEUC1
Sequence: MSDAPIGIFDSGVGGLTVARAVLDQLPHESVLYVGDTARTPYGPRPIAQVREYSLEILDSLVASGVKALVIACNSASAAMLADARERYEGDGVPVVEVIRPAVRRAAAATRNGRIGVIGTRATISSRAYEDAFAAAPQLQLHTRACPDFVELVEDGETSGPAVLASAHAYLDPLRDAGVDTLVLGCTHYPLLAGAISYVMGEGVTLVSSAEETALDVYRTLVAHDLLRSADGARGDDGARSAPRHRFLATGDPAAFTRLARRFLGPEVDDVHDAVEVTGEIPRITAPLRGTR
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: UBIE_RICFE
Sequence: MNQTNFGFKKVDYTKKQGLVNSVFSNVADKYDLMNDLMSFGLHRLWKDEFSRQIPNLNSHILDVASGSGDIALKLAKKARDRGNNIALTLSDINEEMLKNAKKKAIDLNLFQNLKFTVASAEELPFSDNSFDYYTIAFGIRNVPDINKALKEAYRVLKPMGKFICLEFSKVKESYFKDFYKFYSFSIIPTIGQAITGNKEAYEYLVESIELFPSQDEFRIMLKEAGFEEVSYKNLSGGIVAIHSAYKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: AIG2B_ARATH
Sequence: MTSSDKSLSHDVFVYGSFQEPSVVNLILECSPVMVPAQLHGYHVYRLKGRLHACISPSENGLINGKILTGLTDSQLENLDMIEGSEYVRKTVEVVLTDTSEKKQVETYVWANKDDPNLYGEWDFEEWRRLHMDKFIEASTKFIEWKKNPDGRSREEFEKFVFDDPPTAA
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
Protein AIG2 B, Avirulence-induced gene 2 protein B, Putative gamma-glutamylcyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: ACCD_HAEI8
Sequence: MSWINRIFSKSPSSSTRKANVPEGVWTKCTACEQVLYSEELKRNLYVCPKCGHHMRIDARERLLNLLDEDSSQEIAADLEPKDILKFKDLKKYKDRINAAQKETGEKDALITMTGTLYNMPIVVAASNFAFMGGSMGSVVGAKFVKAAEKAMEMNCPFVCFSASGGARMQEALFSLMQMAKTSAVLAQMREKGVPFISVLTDPTLGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDMIVKRSEMRQTLASVLSKLTNQPSPFVEPELISEDE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLS32_PHYTB
Sequence: FFSMIPKIATGIASLVKDL
What is the function of this protein?
Antimicrobial peptide with weak activity against fungus C. albicans ATCC 24433 (MIC=100 uM) (PubMed:29980138).  Not active against Gram-negative bacterium E. coli ATCC 25922 and Gram-positive bacterium S. epidermidis ATCC 12228 at concentrations up to 100 uM (PubMed:29980138).  Has an anti-inflammatory effect, since it inhibits the production of the pro-inflammatory cytokines TNF-alpha, and induces the production of the anti-inflammatory cytokine IL-10 (PubMed:30734396).  Has high activity of stimulation of insulin release, which may protect the species from being eaten by predators by causing fatal hypoglycemia (PubMed:30734396).  Is cytotoxic to cancer line cells (PubMed:30734396).  Shows low hemolysis on mouse erythrocytes (LC(50)=110 uM) (PubMed:30734396).
What are the official names of this protein?
Phylloseptin-3.2TR, PLS-3.2TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_DESRM
Sequence: MSAAAGAAQAAEHHDMLHMVEMDLNFWNIPLFTEYDKYWHIMGLSISPRTMIMTWITMALVLLFAWACTKNQNVRSPGKAQATFEVLWEFLGGQVFSNLGNKLGAAMMPIIVTFFIYIVFANLLGLIPTLSSPTADKNTTFGLALIVVLLIHYHGLKANGVGGHIGHYFQPFKPFVVIHLIEEIARPVTLAFRLYGNIFAGEVLIAVLLGLININAYVFGGFIPSVIWLAFSVFVGFVQAFVFSMLTIAYVSQFAAHEADHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_ECOL6
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KUP2_GEOSL
Sequence: MKTEAQSYWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVTVEYAWLAMSLGRKGEGGTIVLKEILIRLLKSGRQMAFAGFLAFLGVSLLLGDGVITPAISILSAVEGMRLIPGLEDLAQGGLILVAAVIAVFLFIFQFKGTDKVASAFGPIMVVWFSALTVSGLVSIIGTPTVVQAISPHHAVLFLKHNGLAGFFVLSEVILCATGGEALYADMGHLGRKPIIRAWYFVFCALVINYLGQGAFILRNPEAKNILFSMVKSQVPMLYIPFLLLTISATIIASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMILFQRSENLAAAYGLAVTGTMFITGIMMTMIFSRTTKKWKVPIALAVTVIDFAYLTANLHKLPHGGYWSLVLASIPLAIMVIWTRGQRALYRSLKPLDLDTFLLSYEQIYAKGHNIPGTGLFFVRETPVVPPYVIHCIIRSNIIYERNVFVSLTRTDEPFDVRTKLTRGIGTGLDAFEVNAGYMERLDIEKLLKKHGVEEKVIFYGIEDIDTSNPVWRIFATIKRQSANFVQFNKLPVSKLQGVVTRVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPS_VIBC1
Sequence: MSKNFEWVTPDSDLLERESTKVQPPKLYNVVLNNDDYTPMDFVIEVLERFFSHDIDKATQIMLKIHYEGKAICGTYSAEIAETKVAQVTMYSRENEHPLLCTMEQA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: TPM1_MOUSE
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.