PharMolix/UniProtQA huggingface dataset:
Protein: GUAC_STRPI
Sequence: MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVVPANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEYDFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRILLPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: YCF2_HELAN
Sequence: MTGHEFKSWILELREILREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFIKLFDSRIWSILLSHNSQGSTSNRYFTIKGVILFGVAVLIYRINNRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKIYESSFLNPKESTWVLPITKKCSMPESNWGSRWWRDWIGKKSDSSCKISNETVAGIEILFKEKDLKYLEFVFVYYRDDPIRKDHGWEFFDRLSLRKRQNRINLNSGPLFEILVKHWICYLMSAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKSRLFTEREKQMINHMLPEEIEEFLGNPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFLRRSEKKEMVNLFKIITYLQNTVSIHPISLDSGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNRGGYTLHHDFESEDRFQEMADLFTLSITEPDLVYHKRFAFSIDSYGLDPKQFLNGVFNSRYEWKTTSLLVLFPIFYEENESFYRRIRKNRVRISCGNDLEEPKPKIVVFASNNIMEAVNQYRLIRNLIQIQHSTHRYIRNVLNRFFLMNRSDRNFEYGIQRDQIRKDTLNHRTLMKYTINQHLSNLKKSQKRWFDPLIFFYRTERSMNRDPDAYRYKWSTGSNNFQEHLEHFVSEQKSRLQVVFDRLRINPYSIDWSEVIDKKDLSKPLRFFLSKLLLFLSNSLPFLFVSFGNIPIHRSEIYIYQLKGPNDPQFLESIGLQIVHLKKLKPFLLDDHETCQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNRRKSFDNTDSYFSMIFHDQYNWLNPVKSFHRSSLRSSFYKGNQLRFLNNPHHFCFYCNKRFPFYVEKARINNYDFTYGQFLNILFIRNKIFSLCVGKKKHAFWGRDTISAIESQVSNIFIPKAFPQSGDETYNLYKSFHFPSRSNPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLYQYLNFNSNMGLIHTPCSEKYLPSEKRKKRSLCLKKCVEKGQMYRTFQRDSAYSTLSKWNLFQTYMPWFLTSTGYRYLKFLFLDTFSDLLPILSSSQKFVSIFHDIMHGSDISWRILQKKFCLPQWNLISEISSKCFHNLLLSEEMIHRNNESPLISTHLTNVREFLYAILFLLLVAAYLVCTHLLFVFGASSELQAEFEKVKSLMIPSSMIELRKILDRYPTSEPNSFWLKNLFLVALKQLGDSLGGNMLLGGGPAYGVKSIRSKKKYLNINLIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIDDEKREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRDLVDIHKKYLMNYEFNTSSLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSLSRGILVIGSIGTGRSYLVKYLAKNSYLPFITVFLNKFLDNKSQGFDDIDIDDLDASDDLDASDDLDASDDLDASDDILDMELELLTSMNALTMNMMPEDEDQLYITLQFELAKAMSPCIIWIPNIHDLDVNESNYFSLGLLVNLLSRDYETRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSALHRQIWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEVDFYLYNWYFELGTSMKKLTILLYLLSCSAGSVTQDLWSLPGPDEKNGITPYGLVENDSGLVRGLLEVEGALVGSSRTCSQFDKDRVTLLLRPEPRNPLDMMQKGSCSILDQRFLYEKDESEFEEGEGALDRQQIEEDLFNHIVWAPRIWRPWGFLFDCIERPNELGFPYWSRSFRGKRIIYDKEDELQENDSEFLQSGTAQYQTRDRSSKEQGLFRISQFIWDPADPLFFLFKAQPFVSVFSHRELFADEEMSKGLLTPQTNPPTSLYKRWFIKKTQEKHFELLINRQRWLRTNRSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKALLRKRWLFPDEMQIGFMEQEKDFPFLSRKDMWP
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: UBIE_SHIDS
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SCA1_RICFE
Sequence: MNKLTEQNLLKKSRFLKYSLLASISVGAIIAIPFEGMASSKQKALFQNALEKKLSLRLSQSNGNRDTTNTPQQIGTVIVPEPERNTYTSSEIREMEISKQSKASNPLKDIPIEDHYKKVARSKSDVGKARKVRPPTRSKTFVDTEKVEQNQNNYTHEPTEQTPQKPEIIITASSPTVSPASNGFVTAPNTPNTTLTSPEHYTTAPGTPSTPVTPYQPTPDSKPNDNLEAKTPPNTNSKAVRRLSFSSEPQQTVVQPSTQAKPPVPPKPLLLSSAGVVAKKVVSNILRVNEMLGIKLAEVESTIKNTQGKENKKPLQQLKKQIASSQKTTEKLKSEAAKIGIKIKELDEENKSLKTGRVKNKRELDKDNAKLKENNKKIDKLQQKLTNKNNEANRLSEEIDISVKKVVLIKPQVKAPVTEMPPAGSFLNQQQQLEVLTQQQKVNAARQAVVDKKRAEANGVKRNSAEYKDLISEREEIQLEQNQRHIAVEKTKKQQQAEDKEQRQEAQKQLSKIKKQEKAIKAASDEAQKILNDAKKEASRTKLKKLQEQMDNHVAMVTNDKIEENIKKLEGLALTPSTTSSAATISKQSLTAKSTMQLSHELQRTLPEDEDGYLEPIKVQQQPYTVMLSNQEVADPKSMDSGLGSLPSGIETDEDTEFNLGWGNGHHKELILSVDSKLIEKAAQLISGLDVKRSEILQTTSPSQQKSLNLALQGIENDYQEAIEVYQGLQQALIHKSEDIKAYNAEAEKRLDAIKSRADKYFNNIETDADVGFNQDWSNVHTQTAQSDSVLKMQQALLEKRSKEGSNPNFTTYLDPQPGEEGLKSIDSGLGSLPIDASVIPQYVEELNNLASFSSLNQIQQKKPLIITNMLLSETSALSDDEFRAVANEVHPKIRPILTYNRQKEKEAKLVEAEAAHSQVVQNAIKTPNSTQAKEAVENAAKLFGQYNNSFKLTQALRDEHRKKYYETPKKVTDSINSLDLAVPAESQQLKEPRSKSLEALDLAGSVSSQLKQAEYKSVLSPSSSVNSLLSNEDEQNHEFEIPKSLSFSFGSLNSDAESQQLKEPRSKSLEALDLAGSVSSQLKQAEYKSVLSPSSSVNSLFSNEDEQNHEFEILKSLSFSFGSLNSDAESNLSWDNTGDIGVGHRYGAEDSCPTPDQSSSKIANSSDKNSSETKLALLRTYQMAVIVKRQELEQLPSTSSGADQNTQKIKELKEVEVTMHDAINACIADSSKLNDVSFEEINEALKKLGSEIPESAISDFESKAQKDPEAILDGSILQEMLSSKDSLPSGDEEQEDTEVTESGIQKAGDKGLLALPVSSNECALALSDGREKECLALGDGSEEKEETIEQLSDSVEGNLKIEQEEKKEMQTQISKNAPTLNQAKVVNTIVNNMIRNRLDASMNMSNNMVAVGAGDEEESRIKRGLWMRGMYGTNNHGRVENMTGYRGTNKGATIGFDVEIDNNILGIAYSNVHSVFKFKNSKNNDKELIDSHVVSIYGQKELPRNFALQALVSASKNFIKDKTTYSYGDTKIRSNVKHSNHSYNAEALLNYNYLLQNKLVITPNIGLRYGKSRDGVYNETGINVQEIALTMKENNILSGIVGTKVKVPLKDVLKFNNLGLTFQGAVEHNFKEKTQRINRVVKIFDTEFKQNYAIPKQPKTSYNLGTGIIGSIKNTTISLDYNYYLNKHYRSHQGSVKLKVNL
What are the official names of this protein?
Putative surface cell antigen sca1.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PANC_PSEA6
Sequence: MRVISNIASLRDVRRSWQADSKVIAFVPTMGNLHQGHLNLVKEAKLKADIVVVSIFVNPLQFGPDEDLEAYPRTLENDRNVLSEMGVDVLFTPQVKDIYSRGLEQQTFVEVPGISYMICGASRPGHFRGVATIVCKLFNMVQPNMAFFGEKDFQQLQVIKAMVTDLSMNLTVHGVKTTRETDGLAMSSRNQYLNVEQRALAPTLYTRLQEMQQKIESGRRDFSRITSECCEQLAEAGFSIDYIEIRSADTLLQPGHEETNVVILAAAFLGRTRLIDNLQVSLA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_RUTMC
Sequence: MNIRPLHDRVIVRRTQEEKTTESGLIIPDSATEKPSKGEILAIGNGKINDNGDVIALDVKVGDQVLFGQYAGNEIKVDGETLLVVREDDIVAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLEO3_ARATH
Sequence: MADQTRTHHEMISRDSTQEAHPKARQMVKAATAVTAGGSLLVLSGLTLAGTVIALTVATPLLVIFSPVLVPAVVTVALIITGFLASGGFGIAAITAFSWLYRHMTGSGSDKIENARMKVGSRVQDTKYGQHNIGVQHQQVS
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth (By similarity).
What are the official names of this protein?
Oleosin 14.9 kDa.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface (By similarity).
Protein: MSHB2_FRACC
Sequence: MTTATPSSPSTAPLPTRRAMFVHAHPDDEVISTGIALASYAASPDTHVTLVTCTLGEEGEVLVPELIHLRADRGDQLGGYRIGELAGACAALGITDQRFLGGPGRWRDSGMIGTPANDHPRCLWRADLDEAAAELVRIVREVRPQVLVSYDARGGYGHPDHIRAHELTRRAFTDAADPSFAPQAGSVWQVAKRYETALARSSAVAGFEYFRDSAAESNPFAGLTSVDELGVTLVDDADITTELSAPHFFEAKIAAMRSHRTQMSVDGFFFALADGIGQRAWSVEHFVLAEGARGPGDGPDGRERDLFAGLVCEP
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2, GlcNAc-Ins deacetylase 2, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 2.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: BZIP1_ARATH
Sequence: MANAEKTSSGSDIDEKKRKRKLSNRESARRSRLKKQKLMEDTIHEISSLERRIKENSERCRAVKQRLDSVETENAGLRSEKIWLSSYVSDLENMIATTSLTLTQSGGGDCVDDQNANAGIAVGDCRRTPWKLSCGSLQPMASFKT
What is the function of this protein?
Transcription factor that binds to the C-box-like motif (5'-TGCTGACGTCA-3') and G-box-like motif (5'-CCACGTGGCC-3'), ABRE elements, of gene promoters involved in sugar signaling.  Activated by low energy stress both at transcriptional and post-transcriptional mechanisms.  Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response (PubMed:20080816, PubMed:21278122).  Transcription activator of the mannan synthase CSLA9.  Recognizes and binds to DNA-specific sequence of CSLA9 promoter (PubMed:24243147).
What are the official names of this protein?
Basic leucine zipper 1, AtbZIP1, bZIP protein 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MESH1_DANRE
Sequence: MNCSSTAVLLETVNFAAEKHRNQRHKDPEGTPYINHPIGVARILSHEGEITDVEVIQAALLHDTVEDTDTTFEELESVFGATVARIVQGVTDDKSLPKAERERQQVEHAPHCSHQAKLVKLADKLYNLRDLNRCTPEGWSAQRVQEYFEWASQVVKGLRGTNAAIEEKLQQLFLERGVKL
What is the function of this protein?
ppGpp hydrolyzing enzyme involved in starvation response.
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD domain-containing protein 3, Metazoan SpoT homolog 1, MESH1, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the MESH1 family.
Protein: CEDA_CITK8
Sequence: MMKPLRQQNRPVISYVPRVEPAPPEHAIKMDAFRDVWILRGKYVAFILMGEAFQRSPAFTVPESAQRWANQVRQENEIAE
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.
Protein: CST16_BOVIN
Sequence: MFLKATLLLGLAVLGMHVWAIQMEFVDISKDLDYFVVSVEFAVAWFNSDNTEEQAYKLLEVRRAQQKSWTMIYLMELDLGRTICKKHDEDIDNCPLQESPGERKVNCTFIVDSRPWFTQFTLLNST
What are the official names of this protein?
Probable cystatin-16.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SURE_GEOSL
Sequence: MNILVTNDDGVHAPGIVALAEALRLVGTVTVVAPDRERSAVGHALTLHHPLRVTEIMAGIFAVDGTPTDCVNLGIHTLLAEAPDIVVSGVNRGGNLGDDITYSGTVSAALEATLMGIPAIAVSLATNGHGSNYRAAAAFAAQLAREVLDRGLPRDTFLNVNVPDLPAEELGGPVITSQGKRDYGGDIVTKVDPRGRNYYWIGGNEPVFRDIEGTDFHAVKRGRISVTPLHLDLTNYASLSILQSWDLSACRPEAGQPSGALL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSCY_YEREN
Sequence: MNITLTKRQQEFLLLNGWLQLQCGHAERACILLDALLTLNPEHLAGRRCRLVALLNNNQGERAEKEAQWLISHDPLQAGNWLCLSRAQQLNGDLDKARHAYQHYLELKDHNESP
What is the function of this protein?
Required for Yop secretion.  Functions probably as a chaperone which stabilizes YscX within the cell, before its secretion (By similarity).
What are the official names of this protein?
Chaperone protein YscY, Yop proteins translocation protein Y.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_EHV1B
Sequence: MLQPYRKMLIFAVVTVAFAMAVWSTPVPATPSGVGNATWANNSFNITRYDKITMGQVYSNTSNSPIFFVVISERNFRIVNTPLGASVFWIPKGAMNPPQHQPCVANGPEPGDPRGPCVNSTVSLLFNENVEPFLMSKNLLEFEVLPDTYITGWTFERSKTATTKSNPVGVVLSPPRGSPSANTTIRDDGGPKKPLSIIDEYTTLVADLQNFTMTLTYISPFAAVWPIEAFQTGITVMGCDTTQVVAYLGHGFMGLQISSVNNPPLEMIVVPNDVSARILNRRPSRLRLEPPGPHAGPIYKVYVLSDGNFYLGHGMSRISREVAAYPEESLDYRYHLSLANLDTLAMLAELSSGKSTDVSYYMYRIVARLAVATFSLAEVIRLSDYMLLQEAIDVDMNLRLIVPLVMKYAAGGAADSSYTSSDVAMDQFDVAQSQIEKIVSDINVEAELRKPMYEHRSLLRSVYAYSRKPLPNAVALADRLILAMYKEAIKDRITWNSTMREVLFFAVGAAAGSHVILTDEPEPGAPAHKDASLFLSLNRNILLLCTAMCTASHAVSAGLKLEEVMAGLVAGGVQFSLLEVFSPCMASTRFDLAEEEHVLDLLSVIPPRLYTDLNTGFEDDGTTIHSYGRSANGILNSRIAYNFDAVSVFTPELASCSTKLPKVLVVLPIFTNRSYVITRTAPSIGLTYSLDGVNIAKPIVISYITYGNCEVSRATIKSGYLDNPGHTQTCVYCGSVFMRYMVSGAIMDLIYIDDKEVELQLVAGENSTIPAFNPKLYTPSMNALLMFPNGTVTLMSAFASYSSFKVPSTYLWASIGGLLLAILILYIIIKMLCGGVTNDGYKLLLSYE
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: MYG_ANAPO
Sequence: MGLSDQEWQQVLTIWGKVEADLAGHGHAVLMRLFQDHPETLDRFEKFKGLKTPDQMKGSEDLKKHGVTVLTQLGKILKQKGNHEAELKPLAQTHATKHKIPVKYLEFISEVIIKVIAEKHSADFGADSQAAMKKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PFLA_STRMU
Sequence: MIEKVDYEKVTGLVNSTESFGSVDGPGIRFVVFMQGCQMRCQYCHNPDTWAMKNDRATERTAGDVFKEALRFKDFWGDTGGITVSGGEATLQMDFLIALFSLAKEKGIHTTLDTCALTFRNTPKYLEKYEKLMAVTDLVLLDIKEINPDQHKIVTGHSNKTILACARYLSDIGKPVWIRHVLVPGLTDRDEDLIKLGEYVKTLKNVQRFEILPYHTMGEFKWRELGIPYPLEGVKPPTPDRVRNAKKLMHTETYEEYKKRINH
What is the function of this protein?
Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Pyruvate formate-lyase-activating enzyme, PFL-activating enzyme, Formate-C-acetyltransferase-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_FINM2
Sequence: MIIDKLSKRINERSIVCVGLDTSTDYVPEKIKKGKKVSEYLFEFNKEIIDNTKDLVACFKVQIAYYEAHGIEGLIAYKNTLKYLKDNDLISIADVKRGDIANTAKEYAKAHFEGDFEADFITVNPFMGYDTLEHYLPYLESKEKGIFVLMRTSNPGSKDIQYKDYKGQPLYYEIGDNLNKIAKDYLGECNLSCLGFVVGGTQSENANKIRERYPNIMFLIPGYGAQGAKPEDIRVYLDNFKKGIVNSSRGIILNYRKFDDGEENIGKYARKAVEDMRKDIYCE
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: LPXA_CAMJD
Sequence: MKKIHPSAVIEEGAQLGDDVVIEAYAYVGKDTKIGNDVIIKQGARILSDTTIGDHSRVFSYAIVGDIPQDISYKEEQKSGVVIGKNATIREFATINSGTAKGDGFTRIGDNAFIMAYCHIAHDCLLGNSIILANNATLAGHVELGDFTVVGGLTPIHQFVKIGEGCMIAGASALSQDIVPFCLAEGNRASIRSLNLVGIRRRFDKDEVDRLSRAFKTLFRQGDLKENAKNLLENQESENIKKMCHFILETKRGIPVYRGKNNA
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AACC3_ENTCL
Sequence: MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAALRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQFLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLGAPLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEGKPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHEAAQRSCEPSG
What is the function of this protein?
Resistance to antibiotics containing the 2-deoxy-streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin.
What are the official names of this protein?
Aminoglycoside N(3)-acetyltransferase III, ACC(3)-III, Aminocyclitol 3-N-acetyltransferase type III, Gentamicin-(3)-N-acetyl-transferase.
What is the protein family that this protein belongs to?
Belongs to the antibiotic N-acetyltransferase family.
Protein: RAN_MOUSE
Sequence: MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
What is the function of this protein?
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs.  Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis.  Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way.  Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport.  Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins.  RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.  Required for normal progress through mitosis.  The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.  Acts as a negative regulator of the kinase activity of VRK1 and VRK2.  Enhances AR-mediated transactivation.
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
Protein: PA2AC_NAJSP
Sequence: MNPAHLLILAAVCVSPLGASSNRPMPLNLYQFKNMVQCTVPNRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNCYGEAEKISRCWPYFKTYSYECSQGTLTCKGGNNACAAAVCDCDRLAAICFAGAPYNDNNYNIDLKARCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 C, svPLA2, NAJPLA-2C, APLA, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_HELPH
Sequence: MNPLLQDYARILLEWNQTHNLSGAKCLSELEPQITDALKPLEFIKDFKSCLDIGSGAGLPAIPLALEKPEVKFILLEPRIKRAAFLNYLKSVLPLKNIEIIKKRLENYQSPLQVDLITSRAVASSSFLIEKSQRFLKDKGYFLFYKGEQLKDEIACKDTECFMHQKRVYFYKSKESLC
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASN_MONDO
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCLGLSCAVM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
GTPase NRas, Transforming protein N-Ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus.
Protein: HIS4_YERPA
Sequence: MIIPALDLIEGKVVRLHQGDYGQQRDYGNHPLPRLQDYQQQGAQVLHLVDLTGAKDPAARQIPLLRELLAGVDVPVQVGGGIRNEQDVVALLEAGAARVVVGSTAVKQPEMVQQWFERYGAEAIVLALDVRINEAGCKHVAISGWQENSDATLEQIVEQYLPYGLKHVLCTDISRDGTLSGSNVELYQEVCQRYPQVAFQASGGIGCLDDIARLRGSGVQGVIVGRALLDGKFNVKEAIACWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.