PharMolix/UniProtQA huggingface dataset:
Protein: Y1698_BIFLS
Sequence: MGDRNLTPKQFGALGEQYAAAWLEEHGWTTLSRNWHTRYGELDIVMLNPEYTVVFVEVKSRRSMHYGYPQEAITPAKQHNLRKAACDWLLDRRNRVPHTAVRFDVVTIVLRVGRPLVHHIENAF
What are the official names of this protein?
UPF0102 protein Blon_1698/BLIJ_1758.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: YR722_MIMIV
Sequence: MSKQNNRIIPTNRDKKICRKCGYHVCSDHYVANLNKHHEIIKNHNDKINRVNMNDIINIKLLFHILLPRDSFNKDKVISRTHDIVCSLNDDFNNYSSNTNTMNNSKYKNIIKQIFGANTIKQGIYLSSDYQKIIPEKSSNIVFELGEIYYYPVKHKLNLSKYDDISDVESQRHEIEQYVRSSEAGAYEPKKFVNIWIIDMIDTSILGFSNFPWEVVNSCHGIIANRRCFFPEEYGESNYSSFKTFTHHMGHHLGLLHVYNPNHCQSKSCDSSGGSKSIVLDFIIDPLDKINNKKLHIDKEYNPYFTNFMDFTCDKYVSNFTVRQIQEMRFMINKFKPKLNSLLNESQCPIPKYNPETDTISATINFNQRFSNREGSAVPSYEKADNPRMSASQGMINPEIFMGIADPQQPFLKPTVVPTNKNINDLIPNLCGTTLPTRKSGNTQDQIIENIQNVLPSSYMNSEQPKDAYADFKKKYNIIYSEDSYIINHPHNPYLLQQHHQDISAMQQQILEEKNQLRRATIDVPVCGNPYNAGQTVGHYVPPINPEEIDRFNAKRQFAESFNPEMFRPNDPLMYQSPQVDPSCCQKPMDPRLYRPAVPSDPRMGQYMTDPRLFQNGNQTQYQSNPQSNPQFNHQAYSQPNPQAYPQSNPQMYPQQTTFPPRYDPRMNNPYASRATSNGLSPNNVVQQYQSYYDNPSNQQSNQQSNQQSNQQPNQQPNQQPNQQPNQQPNQQSVQQCNQVNQEALNDLRSRNIKASPTVSPGDLINKMNRVNEQLQNIKSSLQQDPDTSTTTRVNTAVGQRSFGVPRVSNDQSKPKFNKFGQPITNSPFVSGNVASTAMSGKITKENISVNPRDASKAPKSRFQRTKPPQAV
What are the official names of this protein?
Uncharacterized protein R722.
What are the subcellular locations of this protein?
Virion.
Protein: IF1_BACCZ
Sequence: MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOA_SCEUN
Sequence: MSILKLHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGVSKAVEHVNKTIAPALVNKKVNVVEQEKIDKLMLEMDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNEDVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAENFKEAMRIGAEVYQNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAISKAGYTDKIVIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLSDLYKGFIKNYPVVSIEDPFDQHDWAAWKKFTASAGIQVVGDDLTVTNPRRITKAVEEKSCNCLLLKVNQIGSVTESLQACKLAQTNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKGRFAGRNFRNPRVN
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Phosphopyruvate hydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SYNS3
Sequence: MITIDLAFSPASADLIDAADDEGTRSRLQEAGDWECELSAWIEALRQDHGNHCPEVVRTCDSLSLGISLLDDASIAELNLHWRQKPTPTDVLSFAALESEMPMVAGQELELGDIVVSVPTARRQALEQKHGLERELRWLVSHGLLHLLSWDHPDEDALAAMLQKQEHLLGMGSNVRS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BURTA
Sequence: MATARKPRGGAGGAAQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAHALAYCVASASVEEIDTLNILHATMLAMKRAVEGLAVRPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOC_BACAN
Sequence: MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTEQLSNLFPKAHITAIDFAESMIAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQWLNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQRAKEEKNIQNETSIGQRFYSKNQLRHICEVETGDVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLRIYERDFTGNEGIMATYHALFMHITKEGKR
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: GCSPA_AZOC5
Sequence: MRYLPLTPEDRTEMLARIGAPSVDALFADIPAAKLDPALADLPAHKTELSVERTLGALSAQNVPAGSVPFFVGAGAYRHHVPATVDHLIQRSEFLTSYTPYQPEIAQGTLQYLFEFQTQVGELTGMEVANASMYDGSTAAAEAVLMAHRVTKRRKAVVAGNVHPHYRETIATLSLYADDAVVALSPVPQGGEDILSAIDGETSCVVVQSPDVFGNIVDLKPIAEKAHAAGALLIAVFTEVVSLGLIEPPGAQGADIVVGEGQSIGNPLTFGGPYVGLFATRQKYVRQMPGRLAGETVDASGKRGFVLTLSTREQHIRREKATSNICTNSGLCALAFTIHLTLLGETGLRKLARLNHANACKLADKLAAVPGVQVLNSAFFNEFTLRVPGKAVDVIEKLAAKGVLGGVPYARLAPKAGLDDLILVAATEINTDEDRAAYAAALKEVLA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: Y1353_XANAC
Sequence: MIKWAIIFAIIGLIAGALGFGGMAGAAMGIAKFLFWAGIIIAIVLFVLGMTIAKKVT
What are the official names of this protein?
UPF0391 membrane protein XAC1353.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3B_PICGU
Sequence: MCGCVGVISNVDENFQVKTIVTMSDIDYEALEKEVPLDDIDFSDLEEQYAVKPDFGIDNFVVVDGAPIAPEAKVPVLIKVLKKLFSTVGEIVEGEEGIHMPLEDGKSKGFLFIQFKTAQMADAAIQQMHGKKLDQKHRLLVNKLSDIEKYGIEGNVPTEFKEPEIPPFKSHGYLKSWLQDEQGRDQIGLHYSDTFGVYWNKRKSPEPVIEPRKGFTSKYAKFSPKGTYLFSIHPQGIQSWGGAQFESISKFIHSQVRLIDFSPNEKYLVTLSPQPIQVPENPAERASYPFGPESNGHKLVIWDLATSEPARTFALPPHLEGQKEMPWPLVKWSHDDKYCARQGPGALAIYETPSFQLLDKKLVKIDDIVDFEWAPAPVYLDTSSQNGPGEHVLSYWTPESSNQTARVALMQIPSRQVLRTINLFQVSDCKMHWQDEAKYLCVKVDRHTKSGKTIFSNLEFFKVTERDIPVEKLELKEVVINFAWEPRSDRFVTISRLDDGALNPAIPKNTIAFYAPETSKTKGGAITSSKYKAFETVVDKHSNTVYWSPKGRFVVIATLARSNGELEFYDCTYEEENVRTTSKNNVKLLKSEKFSGMTNLAWDPSGRFVAAWSSSWIHTIENGYKMFEFTGNMLRDESIDNFNEFLWRPRPPSMLNAADRKKVRKNLRTYSAQFEEADAMEADAATRQLILTRRKQLEEWRAYRAKHASAGHQKKEDKMTVIEEIKEEIIEEKEEIVE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3, p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KORA2_ECOLX
Sequence: MKKRLTESQFQEAIQGLEVGQQTIEIARGVLVDGKPQATFATSLGLTRGAVSQAVHRVWAAFEDKNLPEGYARVTAVLPEHQAYIVRKWEADAKKKQETKR
What is the function of this protein?
In conjunction with KorB, inhibits the transcription of kilA, trfA and korAB operons.  In conjunction with KorC is responsible for the negative control of kilC and kilE operons.
What are the official names of this protein?
TrfB transcriptional repressor protein, Regulatory protein KorA.
Protein: MIAB_HAES1
Sequence: MTQKLHIKTWGCQMNEYDSSKMADLLLNTHGLELTDVPEEADVLLLNTCSIREKAQEKVFHQLGRWKELKKQNPSLVIGVGGCVASQEGEHIRSRAPYVDIVFGPQTLHRLPEMINQIRGGKSAVVDVSFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCSFCVVPYTRGEEVSRPVDDVLFEIAQLAEQGVREVNLLGQNVNAYRGPTHDGGICSFAELLRLVASIDGIDRLRFTTSHPIEFTDDIIDVYADTPELVSFLHLPVQSGSDRVLNLMKRNHTALEYKSIIRKLKKVRPNIQISSDFIVGFPGETDQDFEDTMNLIAQVNFDMSFSFIYSARPGTPAADMPDDVTEEEKKQRLYLLQQRINNQAAQFSRAMLGTEQRVLVEGPSKKDIMELTGRTETNRIVNFAGTPNMIGKFVDIKITDVYTNSLRGEVVRTEDEMGLRIVQSPQVVINRTRKEDELGVGHYQG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_AETCO
Sequence: MEKSWFNFLFSKGELEYRCELSKSMDSFAPIEKTTDRVIYDTDKNLYDWGERSSYYNNVDLLVSSKDIRNFISDDTFFVRDSNKNSYSIYFDIQNQKFEIDNGLSDLEVFFYSYRSSSYLNNRSKSDNDPHYDPSIKDTKYDCNNHINSCIDSYFRSHICIDSHFLSDSKNYNESYIYNLICSKSGKIRESQNYKIRTNMNRSDLIKDFDITQNYNQLWIQCDNCYALIYKKALKFKMNVCEQCGYYLKISSSDRIELSIDPGTWNPMDEDMVSTDPIQFHSREEPYQNRIDSAQKKTGLTDAVQTGTGQLNGIPVALGVMDFQFMGGSMGSVVGEKITRLIEYATTEFLPLILVCSSGGARMQEGSLSLMQMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASFGMLGDIIIAEPYAYIAFAGKRVIEQTLKKAVPEGSQAAESLLRKGLLDAIVPRNPLKGVLTELFQLHAFFPLNKNEIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RL21_SYNP2
Sequence: MSYAIIETGGKQVRVEPGRFYDIERLDVDVDGNHTIEKVLLISDDNGVTVGQPYIDGATVEGTVVDQRRAKKVLVYKMLPKKKTRKKRGHRQYFTRFMIDSIKVGGNVVAAKADA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NNR_MYCTO
Sequence: MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSSTYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: GOG8I_HUMAN
Sequence: MAEETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSIPQTATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANIKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSDVMATQKKKANQLSSPSKAGTEWKLEQSMREEALLKVQLTQLKESFQQLQLERHEYAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGALQAQVKNNQRISLLNRGQEERIREQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKSALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLEEKADLSELVKKKELCFIHHWRERCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNPADEPGPGAPAPQELGAADKHGDLCEVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPFFCWAWLPRRRR
What is the function of this protein?
May be involved in maintaining Golgi structure.
What are the official names of this protein?
Putative golgin subfamily A member 8I, Golgin subfamily A member 8I pseudogene.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
Protein: RL4_STRPY
Sequence: MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGNEFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: URE1_RHILW
Sequence: MPYKISRAAYAGMFGPTTGDKVRLADTELFIEIEKDFTTYGEEVKFGGGKVIRDGMGQSQVTRADGAVDTVITNAVIVDHSGVYKADIGLKDGRIVAIGKAGNPDMQPGVNIIVGPGTEAIAAEGKIVTAGGMDSHIHFIAPQQIEEALMSGMTCMLGGGTGPAHGTLATTCTPGPWHLARMIEAADAFPMNLAFAGKGNASLPGALTEMVLAGATSLKLHEDWGTTPGAIDCCLSVADEYDVQVMIHTDTLNESGFVEDTIGAIKGRTIHAFHTEGAGGGHAPDIIKICGQPNVIPSSTNPTRPYTVNTIAEHLDMLMVCHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKQENGDNDNFRVRRYIAKYTINPAIAHGLSHEIGSVEVGKRADLVLWNPAFFGVKPDMVLLGGSIAAAPMGDPNASIPTPQPVHYRPMFASYGRSLTNSSVTFVSQASLDAGLKGRLGVAKQLVAVKNTRGGISKASMIHNDLTPEIEVDPETYEVRANGELLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_PSEAB
Sequence: MNPNFLDFEQPIADLQAKIEELRLVGNDNALNISDEISRLQDKSKALTENIFGNLSSWQIAQLARHPKRPYTLDYIGYLFSDFEELHGDRHFADDPAIVGGVARLDGSPVMVIGHQKGREVREKVRRNFGMPRPEGYRKACRLMEMAERFKMPILTFIDTPGAYPGIDAEERGQSEAIAWNLRVMARLKTPIIATVIGEGGSGGALAIGVCDQLNMLQYSTYSVISPEGCASILWKTAEKAPEAAEAMGITAERLKGLGIVDKVIDEPLGGAHRDPASMAESIRGELLAQLKMLQGLEMGELLERRYDRLMSYGAP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_HERA2
Sequence: MSRIAQTFERLASQGRTALMPFLTIGYPERDSALSLAQALVAGGADMLELGMPFSDPLADGATIQRTTDIALTNGVDIGFCLETVRQLRATGMSIPLLLMGYFNPMFQYGVERFVAEAKAAGADGFIVPDLPPEEADEFHAAAKAHELDLVFLLAPTSTDARIAKIASLSSGFIYCVALRGVTGARAALADDLGDFLARVRQYSQLPRAVGFGISKPEHVAAVAKMAEGAICASALLDYIGNLPAEERATGAQQFVQSLRDAADRATGYQQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TBB1_DROME
Sequence: MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEVDEN
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MATK_ACEPL
Sequence: MKEYQIHLELDRSQQHNFLYPLLFREYIYALAHDHGLNRSTIPLENGGYDNKSSSLSVKRLISRTYQRIHLSIYAKDSNPNQFIGHNNKFYSQMISEGFSVIVEIPFSLRLVAFLEGKEMAKSQNFQSIHSIFPFFENNFSHLHYVLDVLIPYPIRPEILVRTFRYWVKDASSLHLLRFFLHEYFNWNSLITPKKSNSIFSTRNPRFFLFLYNSHVYEYESIFFFLRNQSSHLRSTSSGPLFERISFYGKVEDLVQVFVNDFQDNLWLFKHPIMHYVRYQGKSVLASKDMPLLMNKWKYYLVNLWQWHFHVWSQPGRIHINHLYKDYIDFLGYLSRGRLNTLVVRSQMLENAFLIDNAMKQFETTVPIIPLIGSLTTARFCNSLGHPISKPTWADSSDSYIIDRFMRICRNLSHYHSGSSKKKSLYRIKYILRVSCVKSLVRKHKSTVRVFLKRLGSEFLEEFFTEEEHVLSLIFPRALFTSRRLYRGRVWYLDIICINDLVNHDKLEIVPN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y794_SODGM
Sequence: MKTKLNELLEFPCPFTYKVMGIAQPELVDQVVEVVQRHAPGDYSPQVKPSSKGNYHSVSITITATHIEQVETLYEELGKIDIVRMVL
What are the official names of this protein?
UPF0250 protein SG0794.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: VA0D1_DANRE
Sequence: MPFSELYFNVDNGYLEGLVRGFKAGILSQADYLNLVQCETLEDLKLHLQSTDYGSFLANEASPLTVSVIDDKLKEKMVVEFRHMRNQSYEPLASFMDFITYSYMIDNVILLITGTLHQRAISELVPKCHPLGSFEQMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLEAFYKFCTTLGGTTADTMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGKLYPEGLAQLARADDYEQVKAVAEYYPEYKLLFEGAGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFSVFYAYVKLKEQECRNIVWIAECIAQRHRAKIDNYIPIF
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).  May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (PubMed:21844891).
What are the official names of this protein?
V-type proton ATPase subunit d 1, V-ATPase subunit d 1, Vacuolar proton pump subunit d 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane. Note=Localizes to centrosome and the base of the cilium.
Protein: PGK_CLOPE
Sequence: MNFNKKTIEDVQVKGKKVLVRCDFNVPLKDGVITDENRLNGAMPTIKYLVDNGAKVILCSHMGKPKGEAKPEFSLAPVAKRLSEMLGKEVVFAADDNVVGENAKKAVAEMKDGDVVLLQNTRYRKEETKNGEELSKELASLAEMFVNDAFGTAHRAHCSTVGVTEYLKPAVCGYLIQKELKFLGDAVETPERPFVAILGGAKVSDKINVINNLLEKVDTLIIGGGMAYTFLKAQGYTVGSSLVEEDKVEYAKEMLAKAEEKGVKLLLPVDHRVAKEFKDVEAVVTEDQNIAEGFMGLDIGPKTEAIYAEAIKDAKTVIWNGPMGVFEFENFNKGTIAVAKAMAEADATTIIGGGDSAAAVNILGFGDKMSHISTGGGASLEFLEGKVLPGIAALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMAL6_MOUSE
Sequence: MADRTAPRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLALHPDKTLIATGQVGKEPYICIWNSYNVHTVSILKDVHTHGVACLAFDSDGQHLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRMVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLTLVRTIQGAHSAGIFSLYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDVYAVAQRYKKIGECNKSLSFITHIDWSLDSKYLQTNDGAGERLFYKMPSGKPLTSKEEIKGIPWASWTCVRGPEVSGIWPKYTEVIDINSVDANYNSSVLVSGDDFGLVKLFKFPCLKKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWRFIPEAVSNGVLETTPQEGGADSYSEESDSDFSDVPELDSDIEQETQINYDRQVYKEDLPQLKQQSKEKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQHAQRLYLGHDDDILSLTIHPVKDYVATGQVGRDAAVHVWDTQTLKCLSLLKGHHQRGVCALDFSADGKCLVSVGLDDFHSVVFWDWKKGEKIATTRGHKDKIFVVKCNPQHADKLVTVGIKHIKFWQQAGGGFTSKRGSFGSAGKLETMMCVSYGRMEDLVFSGAATGDIFIWKDVLLLKTVKAHDGPVFAMYALDKGFVTGGKDGIVELWDDMFERCLKTYAIKRTALSTSSKGLLLEDNPSIRAITLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPICATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMLSFHHRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGRKHTIRPSEAEKIEWDTWTCVLGPTCEGIWPAHSDVTDVNAANLTKDGSLLATGDDFGFVKLFSYPVKGQHARFKKYVGHSAHVTNVRWLHNDSVLLTVGGADTALMIWTREFVGTQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSMEERPPVSRAAPQPEKLQKNNITKKKKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTTPSIHIWDAMTKHTLSMLRCFHTKGVNYINFSATGKLLVSVGVDPEHTITVWRWQEGTKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLYKKGVIGSMEAAKMQTMLSVAFGANNLTFTGAINGDVYVWKEHFLIRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGKILVGTKDGEIIEVGEKSAASNILIDGHMEGEIWGLATHPSKDMFISASNDGTARIWDLADKKLLNKVNLGHAARCAAYSPDGEMVAIGMKNGEFVILLVNTLKVWGKKRDRKSAIQDIRISPDNRFLAVGSSEQTVDFYDLTQGTSLNRIGYCKDIPSFVIQMDFSADSKYIQVSTGAYKRQVHEVPLGKQVTEAMVVEKITWASWTSVLGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLLKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSSDDKYVVSTGGDDCSVFVWRCL
What is the function of this protein?
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 6, EMAP-6, Echinoderm microtubule-associated protein-like 5-like.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.