PharMolix/UniProtQA huggingface dataset:
Protein: DJC10_PONAB
Sequence: MGVWLSKDDYIRDLKRIILCFLIVYMAILVGTEQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGNFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKNSILFLNSLDAKEIYLEVIHNLPDFELLSAHTLEDRLAHHRWLLFFHFGKNENSNDPELKKLKTLLKNDHIQVGRFDCSSAPDICSNLYVFQPSLAVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPANDKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYQYHSYNGWNRDAYSLRIWGLGFLPQVSTGLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYFYESAKRTFQEEQINIRDAKAIAALINEKLETLQNQGKRNKDEL
What is the function of this protein?
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.  Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR.  Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1.  Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate.  Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 10.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: COBS_CORDI
Sequence: MSGKAYFVNGEHGPAIIEGPLTALNWLTILPVPSATAFDRVTGGRVMASVPFIGIVLGIVGGAIAFAATSLGVASIVAATVIVCFWELFTRFMHLDGLADVSDALGSYAPPARAREIIADPATGLIGMGACLISILIHISSFTALLDAHLWWMVMITPMIGRFCAIFGAHSRLKPMNPTGFGAMLIGTVKTHTIIAWLCVLLVICIGVPLAMDRGELITITILGLLCSVTLALVEIRHLHRRFEGMNGDTTGFIMHSATALCALVFAVGVGIVA
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_VIBCM
Sequence: MINEIKKDAQERMEKSVEALKNGLSKIRTGRAHPSLLTGISVDYYGAPTPLNQVANVIAEDARTLAITVFDRELTQKVEKAILMSDLGLNPMSAGTIIRVPLPPLTEERRRDLVKIVRGEAEGGRVAVRNIRRDANNDLKALLKDKEISEDDERRAQEEIQKLTDAAVKKIDDVLAAKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_HELPS
Sequence: MPKKCRHLLQTSDLSLDEIKLLLKKASVYANDFNAVSLETKEKMQNKIIVALFFENSTRTVSSFEIASLRLGAKIVKLNMQTSSASKGETLTDTFKNIYAMQPDAIITRHAFSSAPFKLAEFSQCPLINAGSGVSAHPTQALLDLLTLYQHFGSLENLKGKKIAFIGDVKNSRVANSNIKLLQRLGLEIMLCAPSSMLPSVSLKTTHNIEEAIEFADILMSLRTQTERHNAPIFASLKDYGNAYCITQKRLEAHAKNKEIIILHPGPVHRDIDIESAVLEDKRSKVLEQVKNGVAMRMAVLEFLLLD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PDXJ_HYDCU
Sequence: MNPIFLGLNIDHVATLRQARGTRYPDPVKAALDAEMAGADSITLHLREDRRHIQDADVYRLSELRQTKINLEMAATQEMLEIALKCQPEDVCLVPEKREELTTEGGLDVASQKAWLTDYCAQLAENKTRVSLFIDADDAQIHAAKEVGAPVIEIHTGTYAELTDPAAIKTELERIRKATDLAVSLGLTVNAGHGLHYHNVQAIAAIKEIEELNIGHAIIAQAIFSGLPDAVSEMKRLMVDARQQAYLG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO1_STAAC
Sequence: MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSTIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMHSFIEQVQKELRQAHDKINKADKMDNPDMEKPADLALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: DAPAT_SYNJB
Sequence: MARINDHFLKLKTGYLFPEIARRVQAFATAHPEAQIIKMGIGDVTEPLPEACRTAMIRAVEEMGERATFRGYGPEQGYEWLRQAIARHDFQARNCDIDASEIFVSDGSKCDCGNILDILGHDNTIAITDPVYPVYVDTNVMAGHTGPANERGEYEGLVYLPITAENHFTASLPSQKVDVIYLCFPNNPTGAVATREHLQNWVDYARAHGSLILFDAAYEAYITEPGIPHSIYEIPGARECAIEFRSFSKTAGFTGTRCAFTVVPKSLRGQAADGSWVDLWSLWYRRQSTKFNGVSYIVQRGAEAVYSEAGQAQVQGLVQFYLENARIIRQQLAEVGIQVYGGVNAPYVWVKTPDGLSSWEFFDKLLHTCHVVGTPGSGFGSAGEGYLRLSAFNSRANVEEAMRRIGSVFAGAGAVG
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: GAG_SRV2
Sequence: MGQELSQHELYVEQLKKALKTRGVKVKGNDLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKIPVTAFSYWNLIKDLIDKKEADPQVMAAVTQTEKILKVSSQTDLRDNSHNKDMDLISLESDDEEAKAPSEKMTMSNKSPKKYPAMLASQNNNTDKDPDLSEVDWDGLEDEAAKYHNPDWPPFLSRPPPYNRTAATAPAVMAVVNPKEELKEKISQLEEQIKLEELHQSLIIRLQKLKTGNERVTSSGNIESHSRTPKWPGQCLPKGKYLINKNTEEYPPKDIFPVTETMDGQGQAWRHHNGFDFTVIKELKTAVSQYGATAPYTLAIVESIADNWLTPTDWNTLVRAVLSGGDHLIWKSEFFENCRDTAKRNQQAGNGWDFDMLTGSGNYANTDAQMQYDPGLFAQIQAAATNAWRKLPVKGDPGASLTGVKQGPDEPFADFVHRLITTAGRIFGNAEAGVDYVKQLAYENANPACQAAIRPYRKKTDLTGYIRLCSDIGPSYQQGLAMAAAFSGQTVKDLLNNKNKDRGGCFKCGKKGHFAKDCRDHSNKNPESKVPGLCPRCKRGKHWANECKSKTDSQGNPLPPHQGNGMRGQPQAPKQAYGAVSFVPANSNNPFQNLIEPPQEVQDWTSVPPPTQY
What is the function of this protein?
Capsid protein.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p10]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p14]: Virion.
Protein: FABZ_THEVB
Sequence: MPTLTDSPPTTVLTVTELQQLLPHRYPFLLVDRIIDYVPEKYAVGLKNVTINEPFFQGHFPGRPIMPGVLIVEALAQVGGVVLMQMNWAKDKLSVFAGIDKVRFRRPVVPGDQLILRAELLVVKQQRIGKMQGRAEVNGQLVCEGEMMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_STRU0
Sequence: MDLQQQLEELKQQTLEHLTSLTGDHSKELQDLKVSVLGKKGTLTELLKGLKDLSADMRPIIGKQVNQVRDVLNTAFEEQSRIVEEAKIQAKLESESIDVTLPGRQMKLGNRHILTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQIEGLVVGKNISMGDLKGTLEMIIKKMFGEERKIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKGTGWIEILGAGMVHPRVLEMSGVNSEEYSGFAFGLGQERIAMLRYGINDIRGFYQGDMRFSEQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_CORGL
Sequence: MFEGPLQDLIDELSRLPGVGPKSAQRIAFHLLNVDPSDITRLQEALGGVRDGVQFCRICCNISREEVCRICSDSGRDGGTICVVEEPKDIQVIERTGEFSGRYHVLGGALDPLANIGPRELNISTLLQRIGGVLPDRELADSTPENKLFDATPTVREVILATDPNTEGEATASYLGRLLKDFPDLVISRLASGMPLGGDLEFVDELTLSRALSGRLQI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: CYT_BITGA
Sequence: MHSRLLVAAPHCLLLLLLLPSALPALKVGGLYPRDVMDPEVQEAAAFAVENYNAQSTNDNYFKARRIVEAQSQVVSGVKYYLKMELAKTTCKKIAGKPKLYQEIQNCNLPPENQQEEITCHFEVWSRPWLQKTVLTKDEL
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Bitiscystatin, Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EPMA_ECO57
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: NO66_DROSI
Sequence: MEKVTNSAAAKPQGNNKKQESAYNGTAKDKKKPNLDIETTDSDLLSDIHLDGTKEQKVQTLFSKVFEDTGPSTAKTADRKRRLQAEADANNNDTEKASKLAKTSVATTDMDLRVTRKQHTFYMKVQALLAEHAEKESTKKASKMAKISEADLILFMTQKEIEYYMKVKALIAKCAEEGSKLLDNWTSSKDIAKTADHERRLQAEADAKNNDTKKAGQSAKESVATTDMQLNVIKEQMEHCKKVQALLANESKGAEKESKVLDYSTGPSTSSKEAAAAKTADHERRLLAEADVNNNDTEKAGQSAMESVATQGASATERKQSFSLGLEHTSPIQVNGAALACPLVRKSLPPGEANSCPPPPKRDPAAVKSSVKIIKVKAPEEGNNNNDEKEMSTETSETHKTDSVEEGRRVVKWIIFPIKPNFFFKYFWEQTACLVQRTNPKYFQSLISFKMLDEILIRHHLDFTVNLDVTTYKNGKRETLNPEGRALPPAVWGFYSEGCSIRLLNPSAYLTRLREVCTVLQEFFHCKVEANMYLTPPNSQGFAPHYDDIEAFVIQVEGRKRWLLYEPPKEADHLARISSGNYDQEQLGKPIIDEVLSAGDVLYFPRGTVHQAITEEQQHSLHITLSVYQQQAYANLLETLMPMVLKKAVDRSVALRRGLPLHTFQVLGNAYKANDCGSRQLLVENVQKLVTKYLIPSEDDIDEAVDQMAKKFQHEALPPIVLPSEEVRTVHGARSGADEQGNCVCDYKFNEKTSVRLLRANILRLVTEPDGSVRIYHHADNGLDYCKYEPYFMEILPEEAKAVELLISAYPYYLTIDQLPLKSSARKVEVATALWEHGLLMTEKPFK
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.  Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
What are the official names of this protein?
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Histone lysine demethylase NO66.
What is the protein family that this protein belongs to?
Belongs to the ROX family. NO66 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMI2_YEAST
Sequence: MSFENLHKVNAEALEDAVVEICSSLQVDAAKLDELTAYFIECMEKGLNNTSVGEEKTVDKGLPMIPTYVTSLPNGTERGVLLAADLGGTHFRVCSVTLNGDGTFDMQQLKSKIPEEYLNDKDVTSEELFSYLGRRTRAFVRKHHPELLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWTKSFKIEDTVGKDVVRLYQEQLDIQGLSMINVVALTNDTVGTFLSHCYTSGSRPSSAGEISEPVIGCIFGTGTNGCYMEDIENIKKLPDELRTRLLHEGKTQMCINIEWGSFDNELKHLSATKYDIDIDQKFSPNPGYHLFEKRISGMYLGELLRNILVDLHARGLILGQYRNYDQLPHRLKTPFQLCSEVLSRIEIDDSTNLRETELSFLQSLRLPTTFEERKAIQNLVRSITRRSAYLAAVPIAAILIKTNALNKRYHGEVEIGFDGYVIEYYPGFRSMLRHALALSPIGTEGERKIHLRLAKDGSGVGAALCALVA
What is the function of this protein?
Putative glucokinase involved in phosphorylation of aldohexoses and glucose uptake (By similarity).  Involved in sporulation.  Required for the full activation of the early meiotic inducer IME1.
What are the official names of this protein?
Putative glucokinase-2, Early meiotic induction protein 2, Glucose kinase 2, GLK-2.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRTA_STAAR
Sequence: MALVVKDIVKNFGEGLSETKVLKGINFEVEQGEFVILNGASGSGKTTLLTILGGLLSQTSGTVLYNDAPLFDKQHRSSDLRLEDIGFIFQSSHLVPYLKVIEQLTLVGQEAGMTKQQSSKRAIQLLKNIGLEDRLNVYPHQLSGGEKQRVAIMRAFMNNPKIILADEPTASLDADRATKVVEMIRQQIKEQQMIGIMITHDRRLFEYADRVIELEDGKITD
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative hemin import ATP-binding protein HrtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. HrtA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y762_TREPA
Sequence: MCSARVTPDVVLLFDPQYWNYLHVARAVAPHALLITDISVFPAVFRLPWEYIVLAGSACPFATSLAHHDASCSPSHALPLPFVAPDLLASGGSVATSAWECARYLGATTIVYIGLDLAFPGARTHFRGALFEERAHLQSGRVAPAETTSFCALHSLPLYPVPAASDPHPGKNSPASPTGENKEQTVLTDARFSLYAVWLEAHLARYTHIKTYALEPAGRRVAGITPLRFSQLVTLLNRSAAVPHCRTMYSRRRRLYSRYRNSSVQVNCTDAVRWRRTMKSTPVHCLGHFTKKKKSAEGARNLWRALRRADTRCASPHNLEHALERTRSFLNAMPLTPTTYENKTHALYTALCTLLPTEPTYRARAHAHLFELLTRTLKFCAAYTEEEGEWREA
What are the official names of this protein?
Uncharacterized protein TP_0762.
Protein: RIMP_COREF
Sequence: MAFPTAEELTALIAPVVATRHLDVEGLRVTKAGPKSTVAIKLDSDSRPDLDLLEVVSQEIGELFDAAEARGELSFGAGYLLEVSTPGVDMPLTQPRHWRRNRTRLVSLDVDGKKRIARIGALNAEETAVILIERNKKALSVTVLELANSPRAVVEIEFAKPAQDELDLAGRTFDEAVEETDH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SHEB9
Sequence: MLTIADVEFESRLFTGTGKFSNSQVMLEAITASKSQLVTVAMKRIDFKMGLDDLLTPLRQAGVRLLPNTSGARNAKEAVFAAELAREMLGTHWIKLEIHPDPKYLMPDAIETLEAARILCEKGFIVMPYVHADPVLCRRLEEVGCAAVMPLASPIGSNQGLVTESFLKIIIEQARVPVVIDAGIGAPSQAARAMELGADAVLVNTAIASSASPIVMAECFKEAVQCGRRAFEAGLGRVQTGAVHTSPLTGFLNQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XECA_XANP2
Sequence: MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA
What is the function of this protein?
Involved in aliphatic epoxide carboxylation (PubMed:9405410, PubMed:10411892, PubMed:11939797).  Catalyzes the addition of coenzyme M (CoM) to either R- or S-epoxypropane to form the thioether conjugate 2-hydroxypropyl-CoM (PubMed:10411892, PubMed:11939797).  Catalyzes the reaction of CoM with R-epoxypropane at a rate approximately twice of that with S-epoxypropane (PubMed:10411892).  The CoM analogs 2-mercaptopropionate, 2-mercaptoethanol and cysteine substitute poorly for CoM as the thiol substrate (PubMed:11939797).
What are the official names of this protein?
2-hydroxypropyl-CoM lyase, Aliphatic epoxide carboxylation component I, Epoxide carboxylase component I, Epoxyalkane:CoM transferase, EaCoMT.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: DBP10_CRYNJ
Sequence: MAAITPSWALETTADGEVKEKTSGPGGQWRALNVGPDLIRSLLIRKFKTPTPIQRAAIPPALSTPPRDILGMARTGSGKTLAYLIPLLQRTGSTHHGQGPRALILCPSRELAVQIYTVGKDLARGMNKGKGKGKNKNEDEEDEEGKGKEGLRWALIIGGEGMDAQFEKMSSNPDIVIATPGRFLHLIVEMHMDLRHLQTVIYDEADRLFEMGFDVQLQEILHRLPSTRQNLLFSATLPSSVAEFAKAGLVNPLLVRLDAEQKISPDLALKFFSVKPGEKEASLLVLLREVIGKPNQPEPADPSSAPQAIVFVATKHHVDYVAELLRTTGYRTSLIYSSLDQVARQQQLAGFRSHQSDVLVVTDVAARGLDIPIMDHVINYDFPAGPRIFVHRVGRTARAGRKGTAYSLIVKEDFPYLCDLHTFLGTERMGEPADVLRSLPIEQLSENVEYVFHNLDETAPHITALRNVMRKGQGMFERSRTKANPTSYRQAKSLASALSNNPPRIDDMFEDAMEVEVNEEKARLLAKVAAFTPSETVFEVGKRESESAIIMKKRRKTVDERQKRVSKAEAEKSTASGMEKAPVKELPAPQLPSKNFKDPSFYLDHTQRGAEAEKGYSLKSGVESLSGAITDMTADEGTGPKAQKASQLSWDRKKHKFIKKNGSADGEKMIKSESGALLPASYSSGKYQEWKSKRRHMPDGPVEALALGGGRRGRHGPPGQKRKAEDGDGGEDAGGKGRKDQGKSKGTGKGKDDFKQKSPGKPGKKGIKQSSGLKSAMDIRKQREIAQKRKEKNARKPQKFRK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL22_ECO55
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ARGR_STACT
Sequence: MAKKSVRHIKIREIISTEQVETQDELVRRLNQFDLNVTQATVSRDIKELQLIKVPAPTGQYIYSLPNDRKYHPLEKLGRYLMDSFVNIEGTGNLLVLKTLPGNAQSIGAILDQIDWEEVLGTICGDDTCLLICHDEESANAIKTRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 36DKM_PSEPU
Sequence: MAMETGLIFHPYMRPGRSARQTFDWGIKSAVQADSVGIDSMMISEHASQIWENIPNPELLIAAAALQTKNIKFAPMAHLLPHQHPAKLATMIGWLSQILEGRYFLGIGAGAYPQASYMHGIRNAGQSNTATGGEETKNLNDMVRESLFIMEKIWKREPFFHEGKYWDAGYPEELEGEEGDEQHKLADFSPWGGKAPEIAVTGFSYNSPSMRLAGERNFKPVSIFSGLDALKRHWEVYSEAAIEAGHTPDRSRHAVSHTVFCADTDKEAKRLVMEGPIGYCFERYLIPIWRRFGMMDGYAKDAGIDPVDADLEFLVDNVFLVGSPDTVTEKINALFEATGGWGTLQVEAHDYYDDPAPWFQSLELISKEVAPKILLPKR
What is the function of this protein?
Involved in the degradation and assimilation of (-)-camphor, which allows P. putida strain NCIMB 10007 to grow on this enantiomer of camphor as the sole carbon source (PubMed:8515237).  Catalyzes the FMNH(2)-dependent lactonization of 3,6-diketocamphane via a Baeyer-Villiger oxidation to produce the unstable lactone 5-oxo-1,2-campholide with (S,S) configuration, that presumably undergoes spontaneous hydrolysis to form 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetate (PubMed:23524667).  Is also able to convert (-)-camphor to the corresponding lactone in vitro (PubMed:23524667, PubMed:22286514, PubMed:8515237).  Shows no conversion of (+)-camphor, (+)-fenchone, (-)-fenchone, and (+)-nopinone.  Acts on other bicyclic ketones but very poorly on a few 2- and 4-substituted monocyclic ketones (PubMed:23524667).
What are the official names of this protein?
3,6-diketocamphane 1,6-monooxygenase, 3,6-DKCMO, 3,6-DKMO, 3,6-diketocamphane monooxygenase, 3,6-diketocamphane monooxygenase oxygenating constituent, 3,6-diketocamphane monooxygenase oxygenating subunit, Camphor 1,6-monooxygenase, Type II Baeyer-Villiger monooxygenase, Type II BVMO.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: YB93_SCHPO
Sequence: MVVIANKGALWAYYCKRLLNSVTYMMYPLIRKRTMKKLLLIVGLLLACSTVMRRIPLFHESFHLPSLDPRASTTTSQKFQEYRSDFLEKLETAEPPEDVIMFTAYGLGVHTHNLFMLACDMAKTSDSQIRFLLLTDGTILPEALYDYNRETVSTCPLSFLSYSTGVERLSKELILKDLLSLQFQQALLAISPSVIVTSEHSPLVMFQAINPYLNNNYYTHDTVDTNALEENSWITKLDMQSLQHFRTPRINVVLIVEDGTYKYLLNLMRDLGRDFKNSEEYPHLFIHLFMSENIPNLSSIRANWPQHRLFINLHFNQKDLNLIEVWTPPNDYTYALVVDLQPDSPPQLSSNLITWLKYKILLIYYHKSSSTYKNNIAAIVPSFDFSNEEAVILSQTINSNIVLFAPVVFQKFQEYMAVRLLNPNFELPESNGIEFAHEDSVLGHSKPSLTEFHAILGLYSLVISYNHFEGSLSNEYV
What are the official names of this protein?
Uncharacterized protein C1E8.03c.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CH60_DESVH
Sequence: MASKEILFDTKAREKLSRGVDKLANAVKVTLGPKGRNVVIEKSFGSPVITKDGVSVAKEIELEDKFENMGAQMVKEVASKTSDIAGDGTTTATILAQAIYREGVKLVAAGRNPMAIKRGVDKAVESLVRELGNLAKPTRDQKEIAQVGTISANSDSTIGNIIAEAMSKVGKEGVITVEEAKGLETTLEVVEGMQFDRGYLSPYFVTDPEKMVCELDEPFILCNEKKISTMKDMLPVLEQVAKMQRPLVIIAEDVDGEALATLVVNKLRGALQVVAIKAPGFGERRKAMLQDIAVLTGGQVVSEDMGIKLENISVADLGTAKRVVIDKENTTIVDGAGKGDDIKARVKQIRAQIEETTSDYDREKLQERLAKLVGGVAVIHVGAATETEMKEKKDRVEDALNATRAAVEEGIVPGGGTALVRVAKVLDDIKPADDDETAGVNIIRRAIEEPLRQIASNAGFEGSIVVERVREGKDGFGFNAATGEYEDLIGVGVIDPKKVTRIALQNAASVASLLLTTECAIAEKPEPKKDMPMPGGMGGMGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.