PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_XANP2
Sequence: MNQEVLNVFNPTVPAPAFNQIRITIASPDKIKSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMTLKDLERILYFEYFVVIEPGTTKLKYRQLLSEDEYLRAQDEFGETNFTAMIGAEAIREILRGMDLDKIAADLRVEIAEATTELKPKKLAKRLKIVEAFQQSGNKPEWMILTHVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSRLDAKGHSATVKQAKKLVEKERPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGQPIIVPSQDIVLGLYYLSIMKEKEPGEGMMFANMAEIDHALNAKAITLATKIRGRYNGVDAEGKPYSKIYETSPGRMKIGELLPKHPKLSYDVVNKLMTKKEISNMIDAVYRHCGQKESVIFCDRIMALGFYNAFRAGISFGKDDMVVPKKKWDLVEETRALTKEYEQQYNDGLITQGEKYNKVVDAWGKCSDRVAEEMMKEISSVKKDPKTGREKQINSIYMMSHSGARGSPAQMKQLAGMRGLMAKPSGEIIESPIISNFKEGLTVMEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDSIITERDCGSEKGIHMRAIIDAGQVVASLASRVLGRTAAEDIVEPATGNVIVPRGTMIEEWHVERINKSGIQEIKIRSVLTCETRNGVCGTCYGRDLARGTPVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGAATLADSSYVESNFEGIVRIRNRNVARNSEGDLVVMARNLAVVIVDVDGTERAVNRVQYGARLKVDEGDTIKRGQRIAEWDPYTRPILSEVDGIVAFEDLTEGSSMNETVDESTGIAKRVVTDSRSGRGPELRPAILIKGKDGKIIKLPRGGDARYALPVEAIISVDPNQTLKAGDAVARVPMESAKTRDITGGLPRVAELFEARRPKDAAIIAEISGTIRFGRDYKNKRRLSIEPADGGDAVEYLIPKGKHIHLQDGDVVEKGDFIVDGNPAPHDILAIKGVEELAAFLVNEIQEVYRLQGVHINDKHIEVIVRNMLQKVEIDDSGETDFLDGEQVDRIEFIEANEKAAEEAKKPATGHPVLLGITKASLQTRSFFSAASFQETTRVLTEAAVNGKVDPLEGLKENVIVGRLIPAGTGAQMARLRTIANSRDDLIVATRDEQSEGQPLVQGPADAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: IL4RA_HUMAN
Sequence: MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCPHWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVRCVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS
What is the function of this protein?
Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
What are the official names of this protein?
Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: TM10C_XENTR
Sequence: MAFVNTLLRTIRCSAVHTLVQEGRSLSLLKASHQLTQSRKIMLSNHVRKEEAKSEPNETLDLEEWKSILKSDIGNAEMVKTETQEDSSLNEMQELVEMWRLAGRAVPQSITTEQLQVLMELPTKTARKKYLKYLSVREVMKTNRKEKKKELKESKSKIESLDQLETKEDTPEKKNTFLLHVWDKSIDTMQRWKCVQAMKFGQPLVFDMVYEKNMSRYELENTVCQLMESEGWNRRSTDPFHIYFCSLQPYSMYHKELVKRYIGAWDNVFVTATDKSHVEMFPKEQLVYLTADSPNELKHFDHTKIYIIGSLVDRCQQTGLSLANAKRLNLATARLPLDRYLKWDVGAKNLTLDQMIRILLCLKDTGDWKKALSFVPNRKHDGFAEPAASKKRNIKNDGGMEYAASTKRNLQKNSKMYKFGASKSFIKPERTDDTSIRSTRKRWWEEEN
What is the function of this protein?
Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation.  Component of mitochondrial ribonuclease P, which cleaves tRNA molecules in their 5'-ends.  Together with hsd17b10/mrpp2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity.  The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; trmt10c/mrpp1 acting as the catalytic N(1)-methyltransferase subunit.  The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after elac2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme.  In addition to tRNA N(1)-methyltransferase activity, trmt10c/mrpp1 also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA.
What are the official names of this protein?
tRNA methyltransferase 10 homolog C, Mitochondrial ribonuclease P protein 1, Mitochondrial RNase P protein 1, RNA (guanine-9-)-methyltransferase domain-containing protein 1, mRNA methyladenosine-N(1)-methyltransferase, tRNA (adenine(9)-N(1))-methyltransferase, tRNA (guanine(9)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: CNGB3_CANLF
Sequence: MFKSLTIKSNKVKPREENDENKQDPDPSNQPQQSTRQGENKSENKSLQTKMTPVTFEESHAKMQDKISEKNSLRDLTTNPNHQHPTESKGAMSEQKEMETGKEGLVSPKSKPLGVPVINEYADAQLHNLVRRMRQRTMLYKKKLAEGDISSPEASPQTAKPTAVPSTQESNAKLKEEHYYHILCFKFQKMPLTEYLKRFRLPGSIDSYTDRLYLLWLLLVTIAYNWNCWLIPLRLVFPYQTPDNTHYWFITDITCDIIYLCDMLLIQPRLQFIKGGDIMVDSNELKRHYRSSTKFQLDVASVMPFDVFYLFFGFNPVFRMNRILKYTSFFEFNHHLESIMDKAYIYRVIRTTGYLLYTLHINACIYYWASDYEGIGSTKWVYNGEGNKYLRCYYWAVRTLITIGGLPEPQTSFEIVFQLLNFFSGVFVFSSLIGQMQDVIGAATANQNNFRISMDHTISYMNTYSIPKNVQNRVRTWYEYTWDSQRMLDESDLLCTLPVTMQLALTVDVNLSIISKVELFKGCDTQMIYDMLLRLKSTVYLPGDFVCKKGEIGKEMYIIKQGEVQVLGGSDGAQVLVTLKAGAVFGEISLLAGRGGNRRTANVIAHGFANLLTLDKKTLQEILVHYPDSEKLLMKKASVLLKKKAPATETTPPRKGLAFLFPPKQETPKIFKALLGGTGKAGLTRLLKLKREQTIQKTSENSEEGGGKRREYEDKEREPSEKILDSSECRANCIIAEEMPQSIRRAALPRGTTRQSLIISMAPSAEAGEEVLTIEVKEKAKQ
What is the function of this protein?
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger.  This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.  Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3.  Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones (By similarity).
What are the official names of this protein?
Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRAI_PAESP
Sequence: MRTQVGIIGAGPAGLLLSHLLYLQGIESIIIENRTREEIEGTIRAGVLEQGTVDLMNQMGVGARMMKEGHFHEGFELRFNGRGHRINVHELTGGKYVTVYAQHEVIKDLVAARLQTGGQIHFNVGDVSLHDVDTSSPKIRFRPNKDGELQEIECDFIAGCDGFRGPSRPAIPQSVRKEYQKVYPFSWLGILVEAPPSAHELIYANHERGFALVSTRSPQIQRLYLQVDAQDHIDNWSDDRIWSELHARLETRDGFKLLEGPIFQKGIVSMRSFVCDPMQHGRLFLAGDAAHIVPPTGAKGLNLAAADVQVLARGLEAYYKAGKMEILNRCTEICLRRIWKAERFSWFMTTMLHRDQGHTPFERGIQLAELDYVTSSRAASTSLAENYIGLPMEF
What is the function of this protein?
Involved in the degradation of 4-hydroxybenzoate (4HB) via the protocatechuate (PCA) 2,3-cleavage pathway.  Catalyzes the conversion of 4HB into 2-hydroxypenta-2,4-dienoate (HPD).  It is highly specific for 4-hydroxybenzoate, and is able to utilize both NADH and NADPH as electron donors at approximately equal rates.
What are the official names of this protein?
4-hydroxybenzoate 3-monooxygenase (NAD(P)H), 4-hydroxybenzoate 3-hydroxylase, 4HB 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family.
Protein: RAB5_TOBAC
Sequence: MASRRHNNLNAKLVLLGDMGAGKSSLVIRFVKGQFLEFQESTIGAAFFSSTVSVNNATVKFEIWDTAGQERYHSLAPMYYRGAAAAIIVYDITSTESLARAKKWVQELQKQGNPNMVMALAGNKADLEDKRKVTAEEARLYAEENGLFFMETSAKTATNVNDIFYEIAKRLPRAQPAQNPAGMVLEDKPAQGSQAASCCT
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ULAE_ECOK1
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYFNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: RUP1_ARATH
Sequence: MEALFCSEIPNNNIRSSINDLSSSSSYTWPMIMTSSSSSSSSPTIMNIENIPRCDWDLSLSAVVSSASTGSDAIGAIEFDPTGEIIATGGIARKIRSYRLSSLLESRDDHVTASESYICTPAKLSSLKWRPDFSGRVIGSGDYDGVVTEYDVEKQVPVSERDEHGGRRIWSVDYTLYNGSLIGASGSDDGTVQMWDPRNGGTLEETVRPGGGAAICSVEFDPFGGSSIAVGCADRNAYVYDIRRLVDPLIVLDGHTKTVTYARFMDSHTIVTGSTDGSLKQWDIDNGRRVVRTYRGHVNSRNFVGLSVWRHGGLVVSGSENNQVFVYDKRWEEPVWVCGLGHTNRFGSDRRFVSSVCLRQVDEDWCTLVAGGSDGALEIFSGKQS
What is the function of this protein?
Functions in association with RUP2 as repressor of UV-B-induced photomorphogenesis mediated by UVR8 and HY5, likely in coordination with DHU1 (PubMed:28735869).  Plays a crucial negative feedback regulatory role downstream of UVR8-COP1 to inhibit UVR8 function, balance UV-B-specific responses and ensure normal plant growth.  Is involved in the regulation of photoperiodic flowering and vegetative development.
What are the official names of this protein?
WD repeat-containing protein RUP1, Protein EARLY FLOWERING BY OVEREXPRESSION 1, Protein REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: PUB70_ORYSJ
Sequence: MEAEDDERAEAEAEARREKEAGNAAYRKLYLETAVRHYTRGALLDPRDISFLTNRAAAYLLMSKYKECVRDCDEAVEKGRELRADNKLVARALARKASALLKLAACAADYDPAIRALQQSLAEHYSEETLAKLGEAEEARKEIEERERLDQEAADHHRDRGNDFFKQKRYQEAAMHYTEAMKKNPKDPRVFSNRAQCHIYLGALPEGLEDADKCIALDPTFLKGYLRKAKVQLLMGNYEIALATYVEGLKCDPNNLEVLDGLRRCAACIKRANGGDSRAEDLREILGDLHLNDDLCNKLQKSMDEAAVLKKEASDERLKRIESERLARTLEDLYLSQVQQRKETEESLSRVQQEFEQLKIQQDEVTVELQRVNEQNENLLGQLSDSREHFEWLLSEHDQLLRERDNAVREVEELRQKRGQMLSVLVTAMHCEFSSSEVESATENFSNSLKIGEGGFGCVYKGILRNMTVAIKVLRPDSLQGQSQFEQEVSILSRVRHPHLVTLLGACSESSTLVYEFLPNGSLEDFLMCSDKRQTLTWQARIRIIAEICSALIFLHKNKPHPVVHGDLKPANILLGVNLVSKLSDFGISRLLIQSSTNNTTLYRTMHPVGTPLYMDPEFLSTGELTPQSDVYSFGIVVLRLLTGKPPVGIKNIVEDAMEKGDLNSVIDTSVGEWPHLHIEQLAYLALRCTELSRRCRPDLSGEVWAIVEAIRDAALSSPSSSRSAQDQNSPPSYFICPISQDIMDDPHIAADGFTYEAEAIRSWLCNGHDTSPMTNLLLEHEELIPNRALRSAIQEWLQQHSMSL
What is the function of this protein?
Functions as an E3 ubiquitin ligase.  Is recruited by MODD to promote ubiquitination of BZIP46, a positive regulator of abscisic acid (ABA) signaling and drought stress tolerance.
What are the official names of this protein?
U-box domain-containing protein 70, OsPUB70, Plant U-box protein 70, Receptor-like cytoplasmic kinase 197, OsRLCK197.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: PYRB_STAA2
Sequence: MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RLMH_DECAR
Sequence: MKLAVLAVGHRQPDWVNEGCAEYLKRMPRELAASVTEIKPEARGSKTREQLLAAEKSRIRDAMAAGSRLVVLDEKGDDLTTLKLAKRLETWMQDGRDVALLIGGADGLDEEFKQQADDRLRLSSLTLPHGMARLLLCEQLYRAVSVLKNHPYHREG
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRAM2_CAEEL
Sequence: MSSERRKDNPLRFALILHLLAVLVQGDIQPRFSCYNHYLAGIRTSSVLPISGHSSAPSNVKCIFENDVAFTEIHSALENSYQVMGKKSVNFQVLDLFHLRELVRRSHCTQTLTVTWKNVPEAGKGGLKVVSLLNETTRIEYSGDERQDFLFDETFAGVRHLIPDEDDNESNPTVTTTRLLCKHIPQPECLVRGKFEVDLEANLEWSYAFSFKTDITNQTLFTLRCGDTTSEVRLENDFFIRADGNAPVAVTHLSDATWHTAIVKHNQPDSHFLKIDDFPEIELGKSISDDTDKTITLSISVNGNIQLIDPTDTNDDCMYSFDKPQKRLQETVSTRTMCVGCGCPKLSGTFDGLSKCDEEDENSYNLRRDVDRLSFIHIDNAFDIDSNGAAIPAISTSFKSDSDVGLIFFGYWQNFHGKGRLQVYYHYDTISAVFCKHTDDEECSSCSIRSSEGFGKDQWIQTILWGGGDEIHLAVDSSVCRLQQLSNISLAEVYAIPQISGGAGLFIGGTWHEKKRRGLYKADAEQKYFENTREKAPVLRGCIKDVFVRGSKTDVSEMFEVQKQAMLNEPDDSNAFAVRKYCQSCIPACSEGTRCRSRAPLQDSAMICDCADELQFNTSEGTCNRERDTPVALSTAFLSENQIVLDIQNTKAILSKVWLKFALPKQINQAQRIVEFNSHRETLFNINLETDGTVNVQLHGQDTASRQLNLLDDRVHLLQLQRRTPMGTRHSAKKYDLYIDGFHTVVSDIGKLVLNNVSVTAAETEDEWSSVIVHDLGLSYEYDEHFAISHPSNVIHQVDLHSQLLPYQIRAPDLSKTGILDDSLWEKPAYVTDSEAAPVLESSPHGEVVDFTADIIEPEQLLSGRWILYSLFLTILLCLFILMCIVCYWCVLRPRAMRRTDTGSQRTIIRDSPDYAPVKMRRDSIGGISIDDDGSIGTDDTDLQAYRDIPSHRVKIYRESMVSILVPSIDQPAEAAIVKRSHSTISDQTPSRPHDTSHAPLVAVNDD
What is the function of this protein?
Maintains the normal guidance and termination of axonal branches of VC motorneurons (PubMed:14551437).  By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron (PubMed:28901288).  Plays a role in regulating male mating behavior (PubMed:28901288).
What are the official names of this protein?
Neurexin-related protein bam-2, Branching abnormal protein 2.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon.
Protein: SERC_YERPS
Sequence: MTQVYNFSAGPAMLPVEVLRRAEQELRNWHGLGTSVMEISHRSKEFMQVAEESEKDLRDLLQIPANYKVLFCHGGARAQFAAVPLNLLGDSNSADYIDGGYWAHSAVKEAQKYCTPHVIDVTTHDNGLTGIQPMKQWKLSDNAAYVHYCPNETIDGVAINEQPDFGNKVVVADYSSAILSRPIDISRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHTALPSILDYKVLADNDSMFNTPPTFAWYLSGLVFKWLKEQGGLGEMEKRNQAKAELLYGAIDRTGFYRNQVAIANRSWMNVPFQMAEASLDKLFLSEAEAQGLQALKGHRVAGGMRASIYNAMPIEGVKALTDFMADFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFL_KLEOX
Sequence: MTLNMMLDNAVPEAIAGALTQQHPGLFFTMVEQASVAISLTDARANIIYANPAFCRQTGYSLAQLLNQNPRLLASSQTPREIYQEMWQTLLQRQPWRGQLINQRRDGGLYLVDIDITPVLNPQGELEHYLAMQRDISVSYTLEQRLRNHMTLMEAVLNNIPAAVVVVDEQDRVVMDNLAYKTFCADCGGKELLVELQVSPRKMGPGAEQILPVVVRGAVRWLSVTCWALPGVSEEASRYFVDSAPARTLMVIADCTQQRQQQEQGRLDRLKQQMTAGKLLAAIRESLDAALIQLNCPINMLAAARRLNGEGSGNVALDAAWREGEEAMARLQRCRPSLELESNAVWPLQPFFDDLYALYRTRFDDRARLQVDMASPHLVGFGQRTQLLACLSLWLDRTLALAAELPSVPLEIELYAEEDEGWLSLYLNDNVPLLQVRYAHSPDALNSPGKGMELRLIQTLVAYHRGAIELASRPQGGTSLVLRFPLFNTLTGGEQ
What is the function of this protein?
Required for the inhibition of NifA activity in response to oxygen and low level of fixed nitrogen.
What are the official names of this protein?
Nitrogen fixation regulatory protein.
Protein: ZFY1_MOUSE
Sequence: MDEDEIELTPEEEKSFFDGIGADAVHMDSDQIVVEVQETVFLANSDVTVHNFVPDNPGSVIIQDVIENVLIEDVHCSHILEETDISDNVIIPEQVLNLGTAEEVSLAQFLIPDILTSGITSTSLTMPEHVLMSEAIHVSDVGHFEQVIHDSLVETEVITDPITADTSDILVADCVSEAVLDSSGMPLEQQDNDKINCEDYLMMSLDEPSKADLEGSSEVTMNAESGTDSSKLDEASPEVIKVCILKADSEVDELGETIHAVESETKNGNEAEVTDQSTSIRVPRVNIYMSASDSQKEEEDTEVIVGDEDAGGTAADTPEHEQQMDVSEIKAAFLPIAWTAAYDNNSDEIEDQNVTASALLNQDESGGLDRVPKQKSKKKKRPESKQYQSAIFVAPDGQTLRVYPCMFCGKKFKTKRFLKRHTKNHPEYLANKKYHCTECDYSTNKKISLHNHMESHKLTIKTEKTTECDDCRKNLSHAGTLCTHKTMHTEKGVNKTCKCKFCDYETAEQTLLNHHLLVVHRKKFPHICGECGKGFRHPSALKKHIRVHTGEKPYECQYCEYKSADSSNLKTHIKSKHSKEIPLKCGICLLTFSDNKEAQQHAVLHQESRTHQCSHCNHKSSNSSDLKRHIISVHTKAYPHKCDMCSKGFHRPSELKKHVATHKSKKMHQCRHCDFNSPDPFLLSHHILSAHTKNVPFKCKRCKKEFQQQCELQTHMKTHSSRKVYQCEYCEYSTKDASGFKRHVISIHTKDYPHSCDFCKKGFRRPSEKNQHIMRHHKVGLP
What is the function of this protein?
Probable transcriptional activator.  Binds to the consensus sequence 5'-AGGCCY-3' (By similarity).
What are the official names of this protein?
Zinc finger Y-chromosomal protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y475_CHLL2
Sequence: MSGHSKWATIKRKKAATDQKRGNLFTKLVKEITISAKMGGGDPSGNPRLRLAVDTARANSMPMDNIQRAIKKGTGELDGATYDEITYEGYGPAGIALIIETATDNRNRTVADIRHIMSRNNGSLGESGSVSWMFQRKGSLDVPKSAMQEDALMELLLDAGLEDLDGDDEVYYTVVTDIRDLENAKKALDEAGIAYENAKVDLIPENYIELEADDAEKVIRLIDALENNDDVQVVYTNMEISEKAMDSLNG
What are the official names of this protein?
Probable transcriptional regulatory protein Clim_0475.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_OCEIH
Sequence: MSKIRIYEYAKQNNLASKDVINFLKTENVEVSNHMSAISDEVVKKLDNKFKAKPENAKKGQNQKQSNNQQQNRQKQNQKNQSKPNKNKKQKGPKKNQQQERPAAKPAETPGKITYHGTLTVQDLAGKLNKEPAELIKKLMFLGVMATKNQDIDDDAIELICGEYDVEVEKEIILEDTDLDKYIEEDAEENLQERPAVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQVENDGKKITFLDTPGHAAFTSMRSRGAQVTDIAILVVAADDGVMPQTVEAINHAKAAEVPIIVAVNKMDKEGANPDRVMQELTEHQLIPEDWGGNTIFVNLSAIKNEGIDDLLEMILLVSEVEELKANPNAKAFGSVIDAQLDKGRGSVATLLVQNGTLHVGDPLVVGSTFGKVRAMVNDLGNRVTEVGPSTPVEITGLHGVPQAGDQFLVFKDEKKARQIGEAREQKQIDENRGTQSTVSLDDLFEQIKQGEMKELNIIVKADVQGSVEALAASLQKIEVEGVNVKIIHTGVGAITESDIILASASKAIVIGFNVRPDVNAKNAAESEKVDLRLHRVIYNAIEEIESAMKGLLDPEYQEKVIGQAEVREIFKVSRIGTIAGSYVTDGKITRDAGVRLIRDGVVLYEGELQALKRFKDDVKEVQTNYECGITISNFNDIKEGDTIEAFVMEEIERK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END7_BPT4
Sequence: MLLTGKLYKEEKQKFYDAQNGKCLICQRELNPDVQANHLDHDHELNGPKAGKVRGLLCNLCNAAEGQMKHKFNRSGLKGQGVDYLEWLENLLTYLKSDYTQNNIHPNFVGDKSKEFSRLGKEEMMAEMLQRGFEYNESDTKTQLIASFKKQLRKSLK
What is the function of this protein?
Cleaves DNA cruciform and Y-structures as well as heteroduplex loops.  Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.
What are the official names of this protein?
Recombination endonuclease VII, Endo VII, Gene product 49, gp49.
Protein: RS4_STRAW
Sequence: MANQSRPKVKKSRALGIALTPKAVKYFEARPYPPGEHGRGRKQNSDYKVRLLEKQRLRAQYDVSERQLVRAYERAAKTQGKTGEALVIELERRLDALVLRSGIARTIYQARQMVVHGHIEVNGQKVDKPSFRVKPDDVVMVRERSRQKPLFEVAREGGFAPDGETPRYLQVNLRALAFRLDREPNRKEIPVICDEQLVVEYYAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: IL21_PERMA
Sequence: VVIFLGTVAHKTSPQRPDRLLIRLRHLVDNVEQLKIYVNDLDPELLPAPQDVKEHCAHSAFACFQKAKLKPANTGSNKTIISDLVTQLRRRLPATKAEKKQQSLVKCPSCDSYEKKTPKEFLE
What is the function of this protein?
Cytokine with immunoregulatory activity.  May promote the transition between innate and adaptive immunity.  Induces the production of IgG(1) and IgG(3) in B-cells.  Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers.  Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity).  May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15.  May regulate proliferation of mature B- and T-cells in response to activating stimuli.  In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity).  During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).
What are the official names of this protein?
Interleukin-21, IL-21.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_LACJO
Sequence: MDLFDRINKLKEEGLNEIKQAENQKMLDKIRVELMGRKGELTEILHSMKDIAPENRPKVGQEVNQVRDLFQKQLDEAKNNFLQTLIAKKLEEEKIDVTLPGREGHLGSKHPINIILDDLESYFIGMGYEVVQGPEIETDHYVFEMMNLPKDHPARDMQATFYIDEENLLRTQTSGDQARVLEKHDFSKGPLKMVGPGKVYRRDDDDATHSHQFQQMEGLVIDKNVTMSDLKGTLEMIAKHVFGQDRKTRLRPSYFPFTEPSVEMDVSCFNCDGKGCPICKYTGWIEVLGAGMVHPNVLENAGVDSTVYGGFAFGLGLDRFAILKYGISDIRDFYTNDVRFLAQFRKEED
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BURVG
Sequence: MTATRAPRAARGRVPLDQRGFDFSRPDDIVCGVDEAGRGPLAGPVVAAAVILDPAQPIEGLDDSKALSAKKRDALYDLIVARSRAYCVASASVDEIDTLNILHATMLAMKRAVEGLSLMPTLAQIDGNRCPTLMVRAEAIVSGDALVPSISAASILAKVTRDRMLVELHARHPVYGFDVHAGYGTAKHLAALREHGPCEAHRRSFAPVRAALDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.