PharMolix/UniProtQA huggingface dataset:
Protein: DEF_STRPD
Sequence: MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDILLGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKEAYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQHRIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: B3GA2_MOUSE
Sequence: MKSALCSRFFILLPWILIVIIMLDVDPRRPAPQLTSRPYFSPHAVGCGGSRVPLRRSSPGRDAAEKRNESRPQLQPEPRLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDRATRSELVSSFLARAGLPNTHLHVPTPRRYKRPWLPRATEQRNAGLAWLRQRHQHQSAQPGVLFFADDDNTYSLELFQEMRTTRKVSVWPVGLVGGRRYERPLVKNGKVVGWYTGWREDRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKASNCTKVLVWHTRTEKVNLANEPKYHLDTVNIEV
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2, Beta-1,3-glucuronyltransferase 2, GlcAT-D, UDP-glucuronosyltransferase S, GlcAT-S, Glucuronosyltransferase S.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PSTS_BORBU
Sequence: MKKVIILIFMLSTSLLYNCKNQDNEKIVSIGGSTTVSPILDEMILRYNKINNNTKVTYDAQGSSVGINGLFNKIYKIAISSRDLTKEEIEQGAKETVFAYDALIFITSPEIKITNITEENLAKILNGEIQNWKQVGGPDAKINFINRDSSSGSYSSIKDLLLNKIFKTHEEAQFRQDGIVVKSNGEVIEKTSLTPHSIGYIGLGYAKNSIEKGLNILSVNSTYPTKETINSNKYTIKRNLIIVTNNKYEDKSVTQFIDFMTSSTGQDIVEEQGFLGIKT
What is the function of this protein?
Binds inorganic phosphate with a Kd of 1. 2 uM (PubMed:24318969).  Part of the ABC transporter complex PstSACB involved in phosphate import (Probable).
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NEK1_DICDI
Sequence: MIKKKNSPADKYLIKSQIGSGSYGNTFKVTHKESGQVFCKKSIQVNNQENIEKVLEEGKILTVMDHVNVVKLNDSFFENGNYVIIMEFAENGDLFQKIENQKRSGKPFSDFEIMHYFCQLVIALNYIHSQNIIHRDIKPKNIVLSSSDSGSGSGSGSGSSNDSIPLLKIADFGVSKLMSETDLYANTTAGTPQYVSYEICNKKPYTNKTDIWSLGVVLYELMTLSLPFDGRKETVMRNIQTESTIFKPVNHPNEELSSLLFKLLNKNPESRFSTQQILEQVFIREFIENHMVDFYKRFNFSIDGIFKVISKKLNLAGLNLTKEEKDNLEHKFIFTKMQEMKDRMKAFDTNHINKNQQQQSPQKLENNNNNNNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDKNNNINNNVNYNVLKKVSVELGFNLDNYCYDTDGMLIELVRSKLEGKDRKTYSKCYNYLSNKQSAFTNTNNEY
What are the official names of this protein?
Probable serine/threonine-protein kinase nek1, Never in mitosis protein A-related protein kinase 1, NimA-related protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: FPG_STRCO
Sequence: MPELPEVEVVRRGLERWAAHRTVADVEVLHPRAVRRHVAGPDDFAHRLKDHRIGTPSRRGKYLWLPLEDTDQAVLAHLGMSGQLLVQPHETPAEKHLRIRVRFADALGTELRFVDQRTFGGLSLHDTSADGLPDVIAHIARDPLDPLFDDEAFHHALRRKRTTIKRALLDQSLISGVGNIYADEALWRARLHYERPTATLTRPRTTELLGHVRDVMNAALAVGGTSFDSLYVNVNGESGYFDRSLDAYGREGMPCRRCATPMRRRPWMNRSSYFCPKCQRPPRVTP
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: POCR_SALTY
Sequence: MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAWVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSL
What is the function of this protein?
Positive regulatory protein of pdu and cob operons (PubMed:8071226, PubMed:7559322, PubMed:9023178).  Positively autoregulates its own expression (PubMed:7559322).
What are the official names of this protein?
Regulatory protein PocR.
Protein: DEGS2_BOVIN
Sequence: MGNRAGRSDFEWVYTDQPHTQRRKEMLAKYPAIKALMRPDPYLKWTVTAMVLAQLLACWLAQGLAWRWLFFWAYAFGGCVNHSLTLAIHDISHNTAFGTGRPSRNRWFAIFANLPVGLPYAASFKKYHVDHHRYLGGDGLDVDVPTYFEGRLFCTPARKLLWLALQPFFYTLRPLCVHPKAMTRMELCNTLVQLAADATIYALWGLKPMVYLLASSLLGLGLHPISGHFVAEHYMFLKGHETYSYYGPLNWITFNVGYHMEHHDFPSIPSCNLPLVRKIAPEYYDHLPQHHSWVKVLWDFVFDDSLGPFARVKRVCKLAENRL
What is the function of this protein?
Bifunctional enzyme which acts as both a sphingolipid delta(4)-desaturase and a sphingolipid C4-monooxygenase.
What are the official names of this protein?
Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2, Degenerative spermatocyte homolog 2, Sphingolipid 4-desaturase, Sphingolipid C4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RLI1_SCHPO
Sequence: MSESLTRIAIVSEDKCRPKKCRQECRRSCPVVRTGKLCIEVNPTDRIAFISETLCIGCGICVKKCPFGAINIINLPTNLESEVTHRYSANSFKLHRLPTPRPGQVLGLVGTNGIGKSTALKILSGKMKPNLGRYDNPPDWAEVVKYFRGSELQNFFTKVVEDNIKALIKPQYVDHIPRAIKTGDKTVSGLIKARANNNNFEEVMDHTDLQNLLNREVGHLSGGELQRFAIAAVATQKADVYMFDEPSSYLDIKQRLKAGRVIRSLLATTNYVIVVEHDLSVLDYLSDFVCVLYGVPSMYGVVTLPYSVREGINIFLDGHIPTENLRFRSEALTFRLADASDEITADRTAEYNYPDHVIEQGDFKLTIKSGGFSDAEIIVLLGENGTGKTTFCKWMAKNSDLKISMKPQTIAPKFQGTVRMLFLKKIRAAFLNGKFQSEVCKPLSIDNIIDQEVLNLSGGELQRVAICLALGMPADVYLIDEPSAYLDSEQRIIASKVIRRFIVNSRKTAFIVEHDFIMATYLADRVILFEGQPSRDARCNPPQSLLTGMNTFLKNLDVTFRRDPNTLRPRINKFDSQMDQEQKNAGNYFFLEN
What is the function of this protein?
Component of the multifactor complex (MFC) involved in translation initiation.  Required for the binding of MFC to the 40S ribosome.  Required for the processing and nuclear export of the 60S and 40S ribosomal subunits (By similarity).
What are the official names of this protein?
Translation initiation factor rli1, ATP-binding cassette sub-family E member rli1, RNase L inhibitor.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: SXT1_TAKPA
Sequence: MGAVPGVVLLLMLAVLGIRAAPAPEECHKLTKPVTKADVQSVSGDWVLVWSVANTTERWICENLTSSYVEFKLHSDIIEYTERNLFLGNSCISFYSNLSASTEKQQQFSLNNLQMEEKGVVRPFNDNGTVKFFETCVDCLSMEYSGDIGRFLLIYRRDGVHQNVEVLKAAQDESQKLAECLGFSIDEPFIYDGVSDFCHKKSPEECHKLTKPVTKADVQSVSGDWVLVWSIDENSTISDDWKKLKTSYVEQRVDSGVIRFTERNMLKNNSCMTFKTNMTAGPESQNTFIYTSGKMEENGVVTVLDENGTVKFFETCADCLSMEYSGFFGHFLLIYRRDGVHQNVEVLKAAQDESQKLAECLGFSIDEPFIYDGVSDFCHKKSSPEVKPEQD
What is the function of this protein?
Binds both saxitoxin and tetradotoxin.  May play a role in toxin accumulation and/or excretion.
What are the official names of this protein?
Saxitoxin and tetrodotoxin-binding protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: ACSA_YERPS
Sequence: MSQIHKHPIPAAIAEHALITPEKYQHYYQQSVQNPDEFWGEQGKIIDWIKPYKTVKNTSFDPGHVSIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPDAVAGRIIDSHSKLVITADEGIRAGRAIPLKKNVDEALKNPAITSIKNVVVFQRTGNASYWEDGRDVWWHDLIKEASADCPPEEMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVVDKHKVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNSKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNLGNPQEGVAEGNLVITDSWPGQARTLFGDHDRFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPLATPDILHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLLEEKQSMQTPS
What is the function of this protein?
Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.  Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SUFT_BACSU
Sequence: MEEALKENIMGALEQVVDPELGVDIVNLGLVYDVDMDEDGLTHITMTLTSMGCPLAPIIVDEVKKALADLPEVKDTEVHIVWNPPWTRDKMSRYAKIALGIQ
What is the function of this protein?
Involved in the maturation of iron-sulfur (Fe-S) proteins.  May function as a Fe-S cluster carrier.
What are the official names of this protein?
Fe-S protein maturation auxiliary factor YitW, Iron-sulfur cluster assembly factor YitW.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
Protein: PTC_PHYTB
Sequence: GLVSGLLNSVTGLLGNLAGGGL
What is the function of this protein?
Has no antimicrobial activity against Gram-negative bacterium E. coli ATCC 25922, Gram-positive bacterium S. epidermidis ATCC 12228 and against fungus C. albicans ATCC 24433 at concentrations up to 100 uM (PubMed:29980138).  Has an anti-inflammatory effect, since it inhibits the production of the pro-inflammatory cytokines TNF-alpha and IL-1 beta (PubMed:30734396).  Has high activity of stimulation of insulin release, which may protect the species from being eaten by predators by causing fatal hypoglycemia (PubMed:30734396).  Is not cytotoxic to cancer line cells (PubMed:30734396).  Does not show hemolysis on mouse erythrocytes (PubMed:30734396).  Adopts a mixture of alpha-helical and beta-sheet structures (PubMed:30734396).
What are the official names of this protein?
Plasticin-TR, PTC-TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Plasticin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: MIAA1_BACTN
Sequence: MPTLIVLIGPTGVGKTELSLRLAENFHTSIVSADSRQLYAELKIGTAAPTPDQLKRVPHYLVGTLHLTDYYSAAQYEQEAMEILHQLFTEHEVVVLTGGSMMYVDAICKGIDDIPTVDAETRQVMLQKYEEEGLEQLCAELRLLDPDYYRIVDLKNPKRVIHALEICYMTGKTYTSFRTQQKKERPFRILKIGLTRDREELYDRINRRVDQMMEEGLLDEVRSVLSYRHLNSLNTVGYKELFKYLDGEWELPFAIEKIKQNSRIYSRKQMTWFKRDEEIRWFHPEQETEILEYLRLQNLTHLPSLDTF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: IHOG_DROSI
Sequence: MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHTAHPAHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLRTGTAKANVSQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTTARLELASTSLVDAQEPESPLQWRVSAGNSVLWSCGQQVQSNPSASWSYFRNGVEIKPEFIGTNGNLFLSNVSSESSGSYSCQATNPASGERIQLPGSLQLQVTPEQRSQSKSPHLLKGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVHDAGTYICFQDNGVRPALEHYIKVHVEQPPQIVRPPWADLTNEGDRLKLECEATGVPTPEIYWLLNGHSSIDDTEAELSNNFLILHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPNPNQGSKHKQMYPPTPPNVTRLTDESVMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPEHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLILLLISTCLCVCRRRNSRSRGNNPNKPRMAELRDDFVPLGNCSPTKQRQRTRHIHITLNPLAQQQQQALEEKNDTDQDAPYYQRPSSYDYDPALRRMSSSSLRRSQRTLERAGGSNGSNNGNNNNLNQTAEAGAVENPGKPGRVLMKRPRLSSRSENLSSGSLNSVGV
What is the function of this protein?
Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc).
What are the official names of this protein?
Interference hedgehog.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IHOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: INHA_RAT
Sequence: MVIQPSLLLLLLLTLQDVDSCQGPELVRELVLAKVKALFLDALGPPAMDGEGGGPGIRRLPRRHALGGFMHRTSEPEEEDVSQAILFPATGATCEDQAAAGGLAQEPEEGLFTYVFRPSQHIRSHQVTSAQLWFHTGLDRKSTAASNSSRPLLDLLVLSSGGPMAVPVSLGQSPPRWAVLHLAASAFPLLTHPILVLLLRCPLCSCSGRPETTPFLVAHTRARAPSAGERARRSAPSMPWPWSPAALRLLQRPPEEPSAHAFCHRAALNISFQELGWDRWIVHPPSFIFHYCHGSCGMPTSDLPLPVPGAPPTPAQPLFLVPGAKPCCAALPGSMRSLRVRTTSDGGYSFKYEMVPNLITQHCACI
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBL_SACOF
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL9_LEUCK
Sequence: MKVVFLEDVKGRGKKGEIKEVPDGYANNFLIKNKKAEPATGKNLGAVKGRQKAEEKAAAEALAEAEQLKAKMADEKFVVEVKGKSGADGRLFGAISTKQIVVALAAQKQIKLDKRKLLLNQPIHALGYTNVPVKLHRDVVANLRVHVSEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PYR3_ASPFU
Sequence: MVSSFSSKRLGDTMDSLALGSNWAGGVAIVLFLAPLALHLVSSYLFPSTSTVINSGRAWDIFRTTAKKRFRSDAARLLQNGFEKSPDAFRILTDNGPLLVLSPRYAREVRSDDRLSLDHFIASEFHPDIPGFEPFKLILDPRNPLNTILKTSLTQALEDLSVEVADALSTALTDDSEWHEISPCQTALKLVAQMASKAFIGPEKCRDPKWHNVIITYTHNVYRAAQALHFWPKFLRPIVARFLPACQTLQAQIAEAREILEPLVAQRRADRACRAAQGKPVPSRADVIDWLEDSHGDQPYDPVAAQLLLSFAAIHGTSNLLAQALMDLCTAPDLIRDIRAEITSVLGDAGLTRAALYRLKLMDSALKESQRLAPNRLLSMGRIAQSDMHLSDGLRIPRGTTLMVSAHAMWEPQIYPDPRRYDGYRFYKLRQVPGQEGQHQLVSATEKHMGFGYGKHACPGRFFAAAEIKVALCHILLKYDLEHRGGGPPPRVWSQGIHLFPDPTARIRVRRRKEEISL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pyripyropene A, a specific human acyl-coenzyme A:cholesterol acyltransferase 2 inhibitor (PubMed:20861902).  The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase pyr1 (PubMed:20861902).  Nicotinyl-CoA is then a substrate of polyketide synthase pyr2 to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase pyr6 to yield farnesyl-HPPO (PubMed:20861902).  The next steps consist of an epoxidation of farnesyl-HPPO to epoxyfarnesyl-HPPO by FAD-dependent monooxygenase pyr5 and a cyclization of the terpenoid portion by the terpene cyclase pyr4 to yield deacetyl-pyripyropene E (PubMed:20861902).  The 2 cytochrome P450 monooxygenases pyr3 and pyr9, and the 2 acetyltransferases pyr7 and pyr8 are involved in the conversion of deacetyl-pyripyropene E into pyripyropene A through several cycles of oxidation and acetylation steps (PubMed:20861902).  Pyr7 acetylates deacetyl-pyripyropene E to pyripyropene E which is oxidized to 11-deacetyl-pyripyropene O by pyr3, which is in turn acetylated into pyripyropene O by pyr8 (PubMed:21224862, PubMed:26019565).  Pyripyropene O is then oxidized to deacetyl-pyripyropene A by pyr9 (PubMed:21224862).  Deacetyl-pyripyropene A is finally acetylated to pyripyropene A by pyr8 (PubMed:26019565).
What are the official names of this protein?
Cytochrome P450 monooxygenase pyr3, Pyripyropene synthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NU4C2_MICAN
Sequence: MLTANFPWLSAIILLPLLASFLIPVIPDKEGKTVRWFALGVGLADFILMCYVFLQKYDLSNPNLQLVEKIDWVPQIGLSWAVSVDGISAPLVLLAGLVTTLSILAAWQVDRKPRLFYFLMLLLYAAQIGVFVAQDLLLFFLMWEIELIPVYLLVSIWGGQKRRYAATKFLLYTAAASIFILVAGLAMALYGGGAMTFDMAELGFKDYPLALELVLYAGLLIAFGVKLAIFPLHTWLPDAHGEASAPVSMILAGVLLKMGGYGLIRLNMGLLPDAHIYFAPILAILGVVNIIYGAFASFGQQNMKRRLAYSSVSHMGFVLLGIASFTDVGISGAMLQMLSHGLIAAVLFFLAGVTYDRTHTLALNEMGGIAQAMPKVFALFTAGAMASLALPGMSGFASEITVFIGVTSSDVYSQTFRVVTVFLASVGLILTPIYLLSMLRQVFYGDGSSCDITNILPNKSNEQAVCFGTSCVLPHESEYSDAKPREIFIAVSFLALIVAIGFYPQLATRIYDVKTVAVNSEVRQAYTEIAATRQNIYAETQPDVSAKVASIFQ
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4 2, NAD(P)H dehydrogenase I, chain 4 2, NDH-1, chain 4 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MSYB_ECOLI
Sequence: MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQDGDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGEFQLEPPLDTEEGRAAADEWDER
What is the function of this protein?
Could participate in the normal pathway of protein export.
What are the official names of this protein?
Acidic protein MsyB.
Protein: HBA_TRIIN
Sequence: VLSDEDKTNVKTFWGKIGTHTGEYGGEALERMFLSFPTTKTYFPHFDLSHGSGQIKAHGKKVADALTRAVGHLEDLPGTLSELSDLHAHRLRVDPVNFKLLSHCLLVTLSSHLREDFTPSVHASLDKFLSSVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRMD_COXB1
Sequence: MKLIIGVITLFPQMFDALKSGVIGRALKQDRLTLSFWNPRDYATDPHRTVDDRPYGGGPGMVMKFEPLALALKAAKAQLGENTKVIHLTPQGKLLTQAIVREKIHASPLILLAGRYEGIDERLIEAEVDEEWSIGDYILSGGELPAMVLIDAMTRLLPGVLGHKDSASQDSFTAGLLDYPHYTRPEKIADRPVPSVLLSGDHEAISRWRLKQSLGRTWQRRQDLIKRRSLSENEQRLLDEFFEESS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP3_COCIM
Sequence: MPSMKRRKLSHTPPQGEAEDGFSDSETSQASLQETPGNDEKIEATTTKSFKDLGIIDSLCEACDSLGYKAPTQIQAESIPLALQGRDLIGLAETGSGKTAAFALPILQALMDKPQSMFGLVLAPTRELAYQISQQFEALGSLISVRCAVIVGGMDMVSQAIALGKKPHIIVATPGRLLDHLENTKGFSLRSLKYLVMDEADRLLDLDFGPILDKILKVLPKERRTYLFSATMSSKVESLQRASLSNPLRVSVSSNKYQTVSTLLQNCLIIPHKHKDIYLIYLLNEFPGQSVIIFTRTVNETQRLAILLRALGFGAIPLHGQLSQSARLGALGKFRSRSRNILVATDVAARGLDIPSVDLVLNYDLPSDSKTYIHRVGRTARAGKSGRAFSLVTQYDVEIWQRIEAALGKELDEYKVEKEEVMVLSDRVGEAQRHAITEMKELHENRGKKGATLRNRRIGKGAKRSRDEMDREEG
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3770_SHESA
Sequence: MAIKDWPEGEGPRDKLLVKGAAHLSDAELLAVLLRNGLSGLNAVDLARSLIHEFGGLRSLLCAPKHQVCRLPGVGPVKYAQLQAAAELARRVAQENLQRGQVLTNPDLTRDYLMRQLADRSYEVFAILLLDSQHRVIQFVELFRGTIDSASVYPREVVSLVLEKKAAAVIVCHNHPSGIAEPSQADRRITERLKNALATIDVSLLDHMVVGDREIVSFAERGWIN
What are the official names of this protein?
UPF0758 protein Shewana3_3770.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: ALR_ALISL
Sequence: MTAAAAQIDMSALAHNLQKIKQQAPNSKLLAVVKANGYGHGLLNIAKGAHGVDAFGVARIEEALQLRAGGIVKQVLLLEGFYSAGDLPILVANNIQTAVHCKEQLEALENADLEGPVVVWLKVDSGMHRLGIRPEEYQEYVDRLHACKNVAQPLRYMSHFGCADELDNPTTNEQIETFMSLTDGCQGERSLAASAGLLAWPDSQLDWVRPGIIMYGVSPFSEKTAQDLGYLPTMTLTSHLIAVREVKAGESVGYGAMWTSERDTKIGVIAIGYGDGYPIAAPNGTPVLVNGRKVPVAGRVSMDMLTVDLGPDAEDNVGDEAILWGRDLPAEEVAEHIGTIAYELVTKLTSRVQMQYIP
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: NU5M_ANOGA
Sequence: MNYLVNYCKISFYFLMSISLSLFLISLKFLLMDLVYFIEWEILSLQSMSIVMTFLFDWMSLMFMSFVLLISSLVIFYSNQYMEEDYNINRFILLVLMFVMSMMMLIISPNLISILLGWDGLGLVSYCLVIYFQNVKSYNAGMLTALSNRIGDVALLLAIAWMLNYGSWNYIFYLDMMKNNIEMMIIGGLVMLAAMTKSAQIPFSSWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFNDVLMNWWMAQFLLLVSGLTMFMAGLGANFEFDLKKIIALSTLSQLGLMMSILSMGFYKLAFFHLLTHALFKALLFMCAGSIIHNMKNSQDIRMMGSLSMSMPLTCSCFNVANLALCGMPFLAGFYSKDLILEMVMLSYVNVFSFFLFFFSTGLTVCYSFRLVYYSMTGDFNSSSLHPLNDSGWTMLFSICFLTVMAVIGGSMLSWLMFLNPAMICLPLEMKLLTLFVCIVGGLMGYLISDVKLFFTNKALYFYNFTNFVGSMWFMPVISTLGVINYPLKLGLYSYKSFDQGWSEFFGGQMVYFQLKNYSLYLQEFQSNSLKIYLLSYMLWFIILLMLVVLVN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.