PharMolix/UniProtQA huggingface dataset:
Protein: SYY_SULTO
Sequence: MGILTLNVEEKIKIISKNTAEIVTIDELRKKLEENQKLKGYIGFEPSGLFHIGWLIWAQKLKDLVDVGVDMSILVATWHAWINDKLGGNLDKIKLAGQYAIEVLNAYGVDMSKVRIVYAEDLVKDSNYWALVIRIAKNTSLARMKRALTIMGRKAEEAELDTSKLIYPAMQVADILYQDLDIALGGTDQRKAHMLARDVSDKLGKKKVIAIHTPLLIGLQGGQRMEGVEEDDYLASVKMSKSKPETAIFVHDPPEVVEAKLRSAYCPKGVVIDNPVLQINKYIIFAKDNATLKVERDIKYGGDIEFKSYEELEKIYSEGKLHPLDLKLATARKLNEILDPIRKKLESKTEFTLLVEELEKGVTR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_ASHGO
Sequence: MVNVVLGSQWGDEGKGKLVDLLVSKYDIVARSAGGNNAGHTIVVGGIKYDFHMLPSGLVNPNCQNLIGNGVVIHVPSFFGELEQLEAKGLRDARGRLFISSRAHLVFDFHQRTDKLRELELSGKSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVSEQPEAWAEFETKYRRLLETRQQRYGPFEHDAEEELARYRRYREELRPFVVDSVVFMHNAIQQKKKILVEGANALMLDIDFGTYPYVTSSSTGIGGVLTGLGIPPRCIDEIYGVVKAYTTRVGEGPFPTEQLNEAGDKLQTIGAEYGVTTGRKRRCGWLDLVVLKYSTLINGFTSLNITKLDVLDTFKEIKVGISYSLNGKKLDLFPEDLLVLSKVDVEYVTLPGWDEDITKISRYEDLPENAKSYLKFIEDFVGVPVEWVGTGPGRESMLHKEVS
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSW_WIGBR
Sequence: MNNKKKIVKIFFYDKILFFLLISLSIIGIIIVSSASISFGIRLHNDYFYFAKRNLLYFFLSFFLFFQIIRIPINQLEKYNKIALLINLFLLIIVFIIGNSINGAIRWIKIGFFSIQPSECSKLILFFYISDYIVKKNKELKNKLWGFLKPIIIMLIFVILLLMQPDLGNSLILFLTTLLLFFLAGINLWKCCFMFLFGLLTIFILIIFKPYRIRRILSFLDPWEDPFNSGYQLTQSLMALGRGKIIGTGLGNSIQKLEYLPEAYTDFIFSILGEELGYIGSIIILIMLFFVIFRIFLIGKNSFIQKKFFSGYFSFSVGIWISLQTIMNVGGVIGILPIKGLTLPFISYGGSSLITIFSAIAIVIRSDFELRINKYQAYLKQ
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: XYND_NEOFI
Sequence: MARIMSWHYGKAITLFVCLGPVALSLDTFPDCSSGPLSKLAVCDTSLDVTTRARSLVNAMTFEEKVNNTQYNSPGVPRLGLPAYNWWSEALHGVAGSPGVEFADSGPFSYATSFPQPILLGATFDDDLIKQVATVVSTEGRAFGNAGRAGLDFWTPNINPFRDARWGRGQETPGEDPLHVSRYVYHLVDGLQNGIGPANPKVVATCKHFAAYDLEDWNGVVRHSFNAEVSTQDLSEFYLPPFKSCARDAKVDAVMCSYNALNGVPACADSYLLQTILREHWKWDEPGHWITGDCGAIDDIYNGHNYTKTPAEAAATALNAGTDLDCGTVFPKYLGQAADEGLYTNKTLDKALVRLYSSLVKLGYFDPAEDQPYRSIGWKDVDSPAAEALAHKAAVEGIVLLKNDKTLPLKAKGTLALIGPYANATKQMQGNYEGPPKYIRTLLWAATQAGYDVKYVAGTAINANSTAGFDAALSAAKQADVVVYAGGIDNTIEAEGHDRTTIVWPGNQLDLIDQLSKIGKPLVVVQFGGGQVDDSSLLSNPHVNALLWTGYPSQEGGSAIFDILTGKTAPAGRLPVTQYPADYVNQVPLTDMALRPGSNTPGRTYRWYDKAVLPFGFGLHYTTFKISWPRRALGPYDTAALVSRSPKNVPIDRAAFDTFHIQVTNTGKTTSDYVALLFLKTIDAGPKPYPLKTLVGYTRAKQIKPGEKRSVDIKVSLGSLARTAENGDLVLYPGRYTLEVDVGENQYPTASFTVKGKEAILDSFPQPPETR
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase xlnD, 1,4-beta-D-xylan xylohydrolase xlnD, Beta-xylosidase A, Beta-xylosidase xlnD, Xylobiase xlnD.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EXG1_COCCA
Sequence: MRFSSLLACLGAVGIQAAAIPFQRRVDNTTDSGSLDAAQAAAAIVDGYWLNDLSGKGRAPFNSNPNYKVFRNVKDYGAKGDGVTDDSDAFNRAISDGSRCGPWVCDSSTDSPAVVYVPSGTYLINKPIIFYYMTALIGNPRELPVLKAASSLQALALIDGSPYSNQNGEPGWISTNLFLRQIRNLIIDGTAVAPTSGFQAIHWPASQATTIQNVKIRMTQASNSVHAGIFVENGSGGHMADLDITGGLYGMNIGNQQFTMRNVKISKAVVGISQIWNWGWLYSGLQISDCGTAFSMVNGGSAGKQEVGSAVIIDSEITNCQKFVDSAWSQTSNPTGSGQLVIENIKLTNVPAAVVSNGATVLAGGSLTIQTWGQGNKYAPNASGPSKFQGAISGATRPTGLLQNGKFYSKSKPQYETLSTSSFISARGAGATGDGVTDDTRAVQAAVTQAASQNKVLFFEHGVYKVTNTIYVPPGSRMVGEIFSAIMGSGSTFGDQANPVPIIQIGKPGESGSIEWSDMIVQTQGATPGAIVIQYNLNTALGSGLWDVHTRIGGAKGTNLQVAQCPAVLGQVKPECFSAHTNVHVTKGANGAYFENNWFWTADHDLDDADSTRINIYTGRGFHVEANNVWIWANGAEHHTMYQYQFNAAQDIFAGYIQTETPYFQPTPIAPLPYVSSSKYSDPVYSSSQTSAWGLRLLDAKNVLIYGGGLYSFFDNYDVGCSSPTAPNGFRDCQTRILSIEGSTSVQAFGFSEVGVEWMVTAAGQDKANWKDNLSVYPTTIGYLSYGF
What are the official names of this protein?
Glucan 1,3-beta-glucosidase, 1,3-beta-D-glucanohydrolase, Exo-beta 1,3 glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 55 family.
Protein: MURA_SHIFL
Sequence: MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPB_BARQU
Sequence: MMADTLILASLSSYRAQLLKKAGLNFLIEGASFDEREIGKIEKVKTPKELSCFLASAKAKNVSDRFPDALVIGCDQVLDLEGQIFHKVTSKKEAYQRLCTLSGKTHSLHSAVALFRNGRKIWVEAFSAHMSVRPLSSKFIKRYLAYVGTDVLNSVGVYQIEGEGIHLFEKIDGDFFTIIGLPLLPLLVKLRHLGIICD
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_PSELT
Sequence: MVRIRLTRMGKRHMPFYRIVVVDSRKRRDGAYIESLGYYNPLRKPAEIKVNVERAVEWILKGAQPSETAANILSKAGVLAKVHEMKYGKREKSDEGVS
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GLYCO_ABLVH
Sequence: MLLQIVLLMSLMVFSPCPGKFPLYTIPDKLGPWSPIDIHHLSCPNNLIVEDEGCTSLSGFSYMELKVGFITTIKVSGFTCTGVVTESETYTNFFGYVTTTFKRKHFRPTPEFCRNAYNWKVAGDPRYEESLHNPYPDYHWLRTVTTTKESLLIISPSVVDMDPYDKSLHSKMFPKGTCSGASVPSIFCSTNHDYTLWMPENPKPGMSCDIFTTSKGKKASKGGKVCGFVDERGLYKSLKGACKLKLCGISGLRLMDGSWVSIQNHEEAKWCSPDQLVNIHDFHSDEIEHLIVEELVRKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIVNKTLMEADAHYKSVRTWNEIIPSKGCLKVRERCHPPYNGVFFNGIILSPDGHVLIPEMQSSLLQQHVELLESSVIPLIHPLADPSTVFKRDDEAEDFIEVHLPDVQKQVSGIDLGLSEWERYLIIGASAVVLFALAIIFAVCCRRCKRRKKARTDRIELDRKVSVTSQSGKVIPSWESYKIEAGGHFRS
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: F228A_MOUSE
Sequence: MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP
What are the official names of this protein?
Protein FAM228A.
What is the protein family that this protein belongs to?
Belongs to the FAM228 family.
Protein: NIFVA_CLOPA
Sequence: MGINIVDTTLRDGEQKAGIALSVQDKVEIAKIISEMGVHQIEAGIPAMGGDEKISVSKIAALGLPSKIAAWNRMSTKDIDTSIECGVDIVHISSPVSDLQIKTKLEKDRKWVAENLKRTVIYALEKDCEVTVGLEDSSRADLNFLIQLCEMIFALGVKRVRYADTVGIMEPKELYSQIKKIRDKVPIDIEIHVHNDFGMAISNSFAAFKAGAKFADCTITGMGERAGNCDFLKFVKVIQELTGEKIYTGDFEDIIEKENEIKKILRLNW
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: RS18_PSESM
Sequence: MARFFRRRKFCRFTAEDVKEIDYKDLNTLKAYVSETGKIVPSRITGTKARYQRQLATAIKRARFLALLAYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NKD_DROME
Sequence: MAGNIVKWWKHKILGGYKQFSVQECTTDSEELMYHQVRASSSCSAPPDLLLVSERDNNIQLRSPVVNIITTPPGNASGAGSKQQSHHQTNHHSSGRSHPGHTAHPQDVSSGGSHSKHLRISSTSNGKHGKYSNMQQQLPQDEDVVDAAATMQQQQHTGHAHSRHLHHHKEERIRLEEFTCDVSVEGGKSSQPLQFSFTFYDLDGHHGKITKDDIVGIVYTIYESIGKSVVVPHCGSKTINVRLTVSPEGKSKSQPVVPVPVAAGFSSSHASKLKKLPTGLAAMSKPLAGGGVGSGGASALTTSAGNRRQHRYRPRKLIKSDDEDDDSNSEKEKDAAHAPAADQPSGSGTKATGKSHHHQSQSARYHQKNNSRAEQCCTEQNTPDNGHNTYENMLNLKCCKPEVDQVDCPSHRQHHQSHPNHQMRQQDIYMKQATQRVKMLRRARKQKYQDHCLETRQRSLSVGNDSACPNRHLQLQQPPVGHPQPQSLNHKSASGSPPLGVGGGGDMMLDGVQLRQPRPHSLTPHQHQQQNQQQQQQQRKSAECWKSALNRNDLISIIRESMEKNRLCFQLNGKPQANVSPIRQPAAQQQPQQQQRQRCNTGSKIPTLITNHSPVAQQSPLSCSPPTAEPTTPSIPAAPPAIEVNGQQHHPTHPTHPSHHNHHEHPQPHIPIYHQQLAINPAVLAAQQTHNTAHNKLNLCGYDSFLHATICGGGAAAHSPPATPSNVATVQPIPKKSQKNLLQGYQRLEQSQQQQQQQRSSKDYKNYGNLIYAKLSEQLQQKDREQRRQRHKQQQHQMLQDQPKDASRSEQRPPTSNSSSAGSKIYGDAVECAHLLASEEEDLPPSPQLTSTPSKVVSTDTLIDLNDDVGEAVAEAVTEGGKQSLEAEESGQQVEVELDTSASSSMIHRYVHEHIHHHYHHFKEQQDV
What is the function of this protein?
Cell autonomous antagonist of the canonical Wnt signaling pathway.  May activate a second Wnt signaling pathway that controls planar cell polarity.  Required for neuroblast specification.
What are the official names of this protein?
Protein naked cuticle, dNkd.
What is the protein family that this protein belongs to?
Belongs to the NKD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus.
Protein: RNFG_PECAS
Sequence: MMTTMRRHATTLALFAASTTAVTAVVNMLTEPTISHQAMLQQKMLLDQVVPAELYNSDIQKECYVVTNPALGSSAPHRVFIARQNGEPVAAALESTAPDGYSGAIRLLVGADFHGKVLGVRVTEHHETPGLGDKIEVRISDWITRFNGLMVQGEHDARWAVKKEGGMFDQFTGATITPRAVINSVKRSALYLQTLPPQINTLSACGENQ
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BT5_ARATH
Sequence: MENMDDFSPENVLAPPPPPPPMKKSTDLFMQRSNSFVSKATRDSWDRMFDEAHGADVLIHTDDNGLIYAHSNVIGMASDVIRGMMKQHKRKSHRKSISILGVPHHALRVFIRFLYSSCYEKQDMEDFAIHLLVLSHVYVVPHLKRVCESEFESSLLNKENVIDVFQLALLCDAPRLGLLCHRMILNNFEEVSTSEGWQAMKESHPRLQKELLRSVAYELNSLKQRNRKQKEIQTYTQLYEAMEAFVHICRDGCREIGPTKTETPHMSCGFQACNGLEQLLKHLAGCKLRSIPGGCSRCKRMWQLLELHSRICVDSEQCKVPLCSSLKERMKTQSRKDEKRWKLLVRNVLSTKRIGGSPFFLQAIDVTL
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ and TAZ domain-containing protein 5, BTB and TAZ domain protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOCN_RAT
Sequence: MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
What is the function of this protein?
May play a role in membrane trafficking, specifically in membrane budding reactions.
What are the official names of this protein?
MOB-like protein phocein, Class II mMOB1, Mob1 homolog 3, Mob3, Mps one binder kinase activator-like 3, Phocein, Preimplantation protein 3.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Detected in cell bodies and dendrites of neurons, but not in axons.
Protein: LEXA_DESRM
Sequence: MLNAREEEVLNVIIENVKLKGYPPSVREIGEAVGLSSSSTVHSYLKRLEQKGYLRRDPTKPRAIEVIMSELSKNPSSHPLTSELSRYSDEELISIPLLGEVAAGVPLLAVENYDEKVTLPRSFTGYGEFFMLSVRGDSMIEAGILPGDLVLVRRQESVSNGDIAVALLEDEATVKRFYKEKNRIRLQPENSLLSPIYVQEVKILGKVVGLMRKI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MURD_MICAN
Sequence: MAKAAIIGLGRSGIAAARCLKRDGWQVTLSDRSDSPSLQATKTNLEREGIIVNLGQNLSLEASDLPNLIVVSPGVPWDAPILITAREKGIDTIGELELAWRYLQSSPWLGITGTNGKTTTTALCAAIFQKAGLNAPSCGNIGYAACELALKADKYDWIIAEISSYQIESSRDLSPKIGIWTTFTPDHLSRHQTLENYYQIKASLLQRSDRQILNGDDPYLRQIGVSQWQQAYWTSVQGKAALLGDPSRGVYLQDNWIVAFGELIAPVNLLKMVGSHNQQNLLMAVAAARLAGIEKKAITEAIATFPGVAHRLEYVCTYKGLDFINDSKATNYDAAAVGLQSVPSPAILIAGGEAKAGDDRAWIAEIKAKVATVLLIGDAAADFARRLQSAGYQDYECVETMDRAVQRAAELGPAKEAKVVLLSPACASFDQYPSFEHRGTHFRQLSLQL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSE_SODGM
Sequence: MEFNGTEISTDAQGYLTHLQDWSEALAGEIARREGITLSEAHWQVIHFVRAFYLQYNTSPAVRMLVKAMAQAYGEEKGNSRYLFRLFPEGPAKQATKIAGLPKPVKCL
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Could accept sulfur from TusD (By similarity).
What are the official names of this protein?
Sulfurtransferase TusE, tRNA 2-thiouridine synthesizing protein E.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_SYNP6
Sequence: MALPKIEDVRNLSDADLAEKIAEAKRELFDLRFQRATRQLEKPHLFKHTKHRLAQLLTVERERQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL29_STRS7
Sequence: MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQLDQTARLNEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GLYA2_PSEF5
Sequence: MFSKQDQIQGYDDALLAAINAEEQRQEDHIELIASENYTSKRVMQAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEALAIERAKQLFGADYANVQPHSGSSANSEVYLALLQAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGIDTRTGLIDYDEVERLAVEHKPKMIVAGFSAYSKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILAKANEEIEKKLNAAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKAYQQQVIDNAQAMAGVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKDADAALGRAHITVNKNAVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCTELAGWICDILDHLGDADVEANVARQVAALCADFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_PSEPK
Sequence: MRTLWQHCHVATMADGRYSAIEDAAIVTSAGLIEWIGPRAELAPVEADRTVDLGGAWVTPGLIDCHTHAVFGGNRSGEFEQRLQGVSYAEIAAQGGGIASTVRATRAASEDELFASAHQRVQALMRDGVTTLEIKSGYGLDLANERKMLRVARRLADELPLTVRATCLAAHALPPEYAGRADDYIAHICDEMLPALAGEGLVDAVDAFCEHLAFSPAQVERLFIKARELGLPVKLHAEQLSSLHGSSLAARYQALSADHLEFMTEEDAVAMASAGTVAVLLPGAFYFLRETQLPPMDALRRHGVKIALASDLNPGTSPGLSLRLMLNMGCTCFRMTPEEALAGVTVHAATALGLGDSHGSLQVGKVADFVAWQIERPADLAYWLGGDLPKRVVRMGHEISN
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_MYCBP
Sequence: MELVVGRVVKSHGVTGEVVVEIRTDDPADRFAPGTRLRAKGPFDGGAEGSAVSYVIESVRQHGGRLLVRLAGVADRDAADALRGSLFVIDADDLPPIDEPDTYYDHQLVGLMVQTATGEGVGVVTEVVHTAAGELLAVKRDSDEVLVPFVRAIVTSVSLDDGIVEIDPPHGLLNLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTSA_STRP8
Sequence: MGKKMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK
What is the function of this protein?
Part of an ATP-driven transport system.
What are the official names of this protein?
Metal ABC transporter substrate-binding lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PREA_ECO57
Sequence: MLMLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDKVLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYCRAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMPIVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYIVYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGCIELGEVKFKKGEKEHPVTL
What is the function of this protein?
Involved in pyrimidine base degradation.  Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate.  It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
What are the official names of this protein?
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the dihydropyrimidine dehydrogenase family.
Protein: HEMH_ECO57
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMJ_SHIBS
Sequence: MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGILASIEQQNKGNKAE
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK2_OCEIH
Sequence: MAERQNIFFYYHPDEEMDGKVKALKKISSENGLNVVENSSDASIIVSIGGDGTFLQAVRKTGFRQDCIYTGIMREGQSGLYCDFNIDNFDNMIHSVLHEDLEVRRFPTIKVQINGETPFYCLNEVSIRSTIVKTIVINVCVDGFHFETFRGDGMIVSTPTGSTGYSKSARGAVIDPLIHGFQVSEVASLNNNQYRTLGSSFLLNKDRKLELEILQDGNDHPIISLDNEASPIKRIQNIDVTMDETIIKTVKLKNNSYWERVKRTFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.