PharMolix/UniProtQA huggingface dataset:
Protein: PDZD7_PONAB
Sequence: MAQGFAVGFDPLGLGDLSSGSLSSLSSRGHLGSDSGSTATRYLLRKQQRLPNVPPRGIRASSPMGRVILINSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVKVLTGSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCSSTPSDTSSEDGIRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVFSCASSAPYSSDSLPSDRMDICLGPEEPGSRGPGWGRADTAMQTEPDAGGRVETWCSVRPTVILRDTTIRSDGPQPGRCLDSAISESPKTALLLALSRPRPPITRSQSYLTLWEEKKQRKKEKSGSTGEKGALQRSKTLMNLFFKGGRQGRLARDGRREAWTPDSGSLAKTCPRLDMEKAGGMGPVQKFVTWRLRRDRERGRALLSARSGSPSSQLPNVDEQVQAWESRRPLIQDLAQRLLTDDEVLAVTRHCSRYVHEGGIEDLVRPLLAILDRPEKLLLLRDIRSVVAPTDLGRFDSMVMPVELEAFEALKSRAVRPPALRPARQDTPPKRHLITPVPDSRGGFYLLPVNGFPEEEDDEELRERLGALKVSPSASAPRHPHKGIPPLQDVPVDAFTPLRSACTPPPQLPHVARRPPRPNWLLTEPLSREHPPQSQIRGRAQSRSRSRSRSRSRSRSSRGQGKSPGRRSPSPVPIPAPSMANGRYHKPQKARPPLPRPLDGEAAKMGAKQGSSENGTGGTAEEAAMKTPSGELKTVTLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLSGALQAGFELVAVDGESLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPSPRPSPSDSSALTDGGLPAAHQPLDAAPVPAHWLPEPPTNPQTPPTDARLL
What is the function of this protein?
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links.  Blocks inhibition of adenylate cyclase activity mediated by ADGRV1.
What are the official names of this protein?
PDZ domain-containing protein 7.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus. Cell projection, stereocilium. Note=Localizes at the ankle region of the stereocilia.
Protein: NCAP_SENDA
Sequence: MAGLLSTFDTFSSRRSESINKSGGGAVIPGQRSTVSVFVLGPSVTDDADKLFIATTFLAHSLDTDKQHSQRGGFLVSLLAMAYSSPELYLTTNGVNADVKYVIYNIEKDPKRTKTDGFIVKTRDMEYERTTEWLFGPMVNKSPLFQGQRDAADPDTLLQIYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFRQDGTVKGALVFTGETVEGIGSVMRSQQSLVSLMVETLVTMNTARSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLIDTYLSKGPRAPFICILKDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDAESKISSALEDELGVTDTAKERLRHHLANLSGGDGAYHKPTGGGAIEVALDNADIDLEPEAHTDQDARGWGGDSGDRWARSTSSGHFITLHGAERLEEETNDEDVSDIERRIARRLAERRQEDATTHEDEGRNNGVDHDEEDDAAAAAGMGGI
What is the function of this protein?
Encapsidates the genome in a ratio of one N per six ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure with 13. 07 N per turn.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: SYQ_RHOBA
Sequence: MARANRGEHSTLSTFWQSRHNAASFDPLYRRIDVNAPEPSDSATPEKTPSKHFIRQAIDADLASGRFDGVATRFPPEPNGYLHIGHAKSICLNFGLAKDMGGTCNLRFDDTNPIKEDTEYVDSIQEDVRWLGFEWDNLHFASDYFDQLYDWAEQLVKDGKAYVCDLTAEETREYRGTLTEPGKNSPHRDRTPEKNLELLRAMKAGKFKDGEKTLRAKIDMASPNINLRDPVMYRIAHVPHHRTGDKWCIYPMYDWAHGQSDSLEKITFSICTLEFEHHRPLYNWYCENLGIHHPRQIEFARLNMTFTVMSKRKLLQLVKENHVTGWDDPRMPTLVGLRRRGYTPESIRSFCADIGVAKFNSTIDVIRLENSVREHLNSVAPRRMAVLDPIKLTITNWPEGKVEMMNAINNPEDESAGSREIPFSGELYIETEDFREEAPRKFFRLKKGGSVRLRSGYIVDCHDVVKDADGNVTEVLCTYDPETKSGEDTSGRKVKGTIHWVSREHAQKVTVRNYDRLFKVENPDASSDTGSFLDHLNPDSLTTLTAHVEPALAEAAVGDRVQFERLGYYVVDPDSTDGEIIFNRIVPLRDTWGKIEAKGKK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRP3_BOVIN
Sequence: MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYCKVCYGRRYGPKGIGYGQGAGCLSTDTGEHLGLQFQQSPKQARSATTSSNPSKFAKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKNFGPTGIGFGGLTHQVEKKD
What is the function of this protein?
Positive regulator of myogenesis.  Acts as cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6.  Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis.  Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes.  Could play a role in mechanical stretch sensing.  May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures.  It is essential for calcineurin anchorage to the Z line.  Required for stress-induced calcineurin-NFAT activation.  The role in regulation of cytoskeleton dynamics by association with CFL2 is reported conflictingly.  Proposed to contribute to the maintenance of muscle cell integrity through an actin-based mechanism.  Can directly bind to actin filaments, cross-link actin filaments into bundles without polarity selectivity and protect them from dilution- and cofilin-mediated depolymerization; the function seems to involve its self-association.  In vitro can inhibit PKC/PRKCA activity.  Proposed to be involved in cardiac stress signaling by down-regulating excessive PKC/PRKCA signaling (By similarity).
What are the official names of this protein?
Cysteine and glycine-rich protein 3, Cysteine-rich protein 3, CRP3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere. Note=Nucleocytoplasmic shuttling protein. Mainly cytoplasmic. In the Z line, found associated with GLRX3 (via C-terminus) (By similarity).
Protein: RS8_CLOB6
Sequence: MVMSDPIADLLTRIRNANVVRHEVVEVPSSNIKKAIANIMLTEGYIRDLEEYRDGSVDMLRISMKYGQNKERIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVVSTSKGIVTDREARKLGVGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL32_ALISL
Sequence: MAVQKSKKSRSMRGMRRSHDALTTMALSVDPTSGETHLRHNVTADGFYRGRKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: HIS8_FRACC
Sequence: MIFKAAGSGAEDRPWRPWDADGLPLRDSLRGLSPYGAPQLDVPVRLNTNENPHPPSVGLVDAIGKAAALAATEANRYPDRDAEALRADLAYYLTPDAGFGVHTSQVWAANGSNEILQQLLQAFGGPGRVALGFEPSYSMHRLIALATATEWVAGQRAEDFTLSPAVVTDAIARHRPALVFLCSPNNPTGTALPPEVVAAACEAVEATGSGMVVVDEAYAEFRRAGVPSTLTLLPRHPRLVVTRTMSKAFALAGARVGYLAAHPAVVDSLYLVRLPYHLSSFTQAVARTALAHADELLGTVEAVKAQRDRIVRELPALGLRLAPSDANFVFFGRFADQRAVWQSLLDAGVLVRDVGLTGWLRVTAGLPNEVDAFLGALGRTLTGSVIGADGVISLATA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HISX_STRMU
Sequence: MKRLTGTNEKISNILYQEQLELSKENLDVEATVREIIEKVKEEGDEALRAYSEKFDHVVLSELHVSDQVVNEAFDKIDKDVLTALENAKANIESYHKQQLKGGFEDQPSQGVLRGQLIRPIERVGVYVPGGTAAYPSSVLMNVIPAKIAGVKEIIMITPPQEHFVPAILVAAKLAGVDKIYQVGGAQGIAALAYGTQTLPKVDKITGPGNIFVATAKKLVYGVVGIDMIAGPSEIGVIADSTANPVYVAADLLSQAEHDVHARAILVTNSAELADAVELEIEKQLQTLPRQAIARPSIENNGRIIIAQDVESMFELMNLVAPEHLEIAIDKAYDYLERVQNAGSIFLGHYTSEPIGDYYAGANHVLPTTATSRFSSALGVHDFVKRIQYTQYSKAAVNAAEKDITTLAYAEGLQAHARAIEVRNDKN
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: RL10_CROS8
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTAFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMSTMKEAAAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SUB6_ARTBE
Sequence: MGFITKAIPIVLAALSTVNGARILEAGPHAETIPNKYIVVMKKDVSEEAFSAHTTWLSQTLNSRLMRRAGSSKPMAGMQDKYSLGNVFRAYSGEFDEAMIKDISGHDDVDFIEPDFVVRTTTNGTNLTHQDNVPSWGLARVGSKQAGGTTYYYDPSAGKGVRAYIIDTGIDTDHKDFGGRAKWGKNFADDMDQDCNGHGTHVAGTVGGTQYGLAKSVSLIAVKVLDCEGSGSNSGVIKGMEWAMRDASGGGNGTAKAAGKTVMNMSLGGPRSEATNQAAKAISDAGIFLAVAAGNENMDAQHSSPASEPSVCTVAASTKDDGKASFSNYGSAVDVYAPGKDITSLKPGGSTDTLSGTSMASPHVCGLGAYLIGLGKQGGPGLCDTIKEMANDAIQSPGEDTTSKLIYNGSGK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2507_BACFR
Sequence: MELLRNLFEGYPNLWGGGVAHSVLILSLVIAFGIMLGKIKVAGISLGVTWILFVGIVFGHFNLNLNEHLLHFLKEFGLILFVYSIGLQVGPGFFSAFKKGGFTLNMLAMIVVFAGVIITLALHFITGIPITTMVGILSGAVTNTPGLGAAQQANSDLTGIDAPEIALGYAVAYPLGVVGCIMSLLGLKYLFRINTKQEEAEAEQGLGHLQELTVRPVSLEVRNEALHGKRIKDIRPLVNRNFVVSRIRHLNGKKESELVNSDTELHLGDEILVIATPIDIEAITAFFGKPIEVEWEQLNKELISRRILITKPELNGKTLAQLKIRNNFGASVTRVNRSGVDLVASPQLQLQMGDRVTIVGSELAVSHAEKVLGNSMKRLNHPNLIPIFLGIALGCILGSIPFMFPGIPQPVKLGLAGGPLIVSILISRFGPQYKLITYTTMSANLMIREIGISLFLACVGLGAGDGFVETIIHEGGYVWIAYGMIITIVPLLLAGFIGRYAFKLNYYTLIGVLAGSTTNPPALAYSNDLTSCDAPAVGYATVYPLTMFLRVLTAQLLILSLG
What are the official names of this protein?
Uncharacterized transporter BF2507.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH_WOLPM
Sequence: MSKKEVIIYTDGACSGNPGAGGWAAIILFQDYRKDIYGREENTTNNKMELTAVINGLKVLKFSCNINLYTDSLYVKHGITEWINKWKMNGWKTSNKKSVKNMELWKELDNVASQHEIDWKWVKAHSGDKYNEEADSLARKAIIDA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVCB_XENNA
Sequence: MNTYEIDCHVELVKPFGLLITPNYPEQDINSLPVDALRKLAQDHLLVILRGFQSGFTDKEKLTEYTRHWGELMTWPFGVVLDVMEQSIPSDHVLDSSYIPLHWDGMYREAIPEFQIFHCVSAPEAAQGGRTTFVNTEQLILDASEDEFNTWKNTTITYRTKKVTHYGGEVVSPLVCLHPKGNKWVIRYNEPMHQEDKYADHHSVTIQGLLSEEQKAFEETLYNRLYDPRYFYAHQWQSGDMVISDNFSLLHGREAFISRSPRHLQRVHVHGMPVCENNSFRTISDSNSIDSTVKEV
What is the function of this protein?
Involved in the biosynthesis of rhabduscin, a tyrosine derivative which is a potent inhibitor of phenoloxidase, a key component of the insect's innate immune system (PubMed:22711807).  Catalyzes the 2-oxoglutarate-dependent oxidative decarboxylation of tyrosine isonitrile (PubMed:25866990).
What are the official names of this protein?
Tyrosine isonitrile desaturase/decarboxylase, Rhabduscin biosynthesis protein PvcB, XnPvcB.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: VGR1A_PSEAE
Sequence: MQLTRLVQVDCPLGPDVLLLQRMEGREELGRLFAYELHLVSENPNLPLEQLLGKPMSLSLELPGGSRRFFHGIVARCSQVAGHGQFAGYQATLRPWPWLLTRTSDCRIFQNQSVPEIIKQVFRNLGFSDFEDALTRPYREWEYCVQYRETSFDFISRLMEQEGIYYWFRHEQKRHILVLSDAYGAHRSPGGYASVPYYPPTLGHRERDHFFDWQMAREVQPGSLTLNDYDFQRPGARLEVRSNIARPHAAADYPLYDYPGEYVQSQDGEQYARNRIEAIQAQHERVRLRGVVRGIGAGHLFRLSGYPRDDQNREYLVVGAEYRVVQELYETGSGGAGSQFESELDCIDASQSFRLLPQTPVPVVRGPQTAVVVGPKGEEIWTDQYGRVKVHFHWDRHDQSNENSSCWIRVSQAWAGKNWGSMQIPRIGQEVIVSFLEGDPDRPIITGRVYNAEQTVPYELPANATQSGMKSRSSKGGTPANFNEIRMEDKKGAEQLYIHAERNQDNLVENDASLSVGHDRNKSIGHDELARIGNNRTRAVKLNDTLLVGGAKSDSVTGTYLIEAGAQIRLVCGKSVVEFNADGTINISGSAFNLYASGNGNIDTGGRLDLNSGGASEVDAKGKGVQGTIDGQVQAMFPPPAKG
What is the function of this protein?
Part of the H1 type VI secretion system (H1-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection (PubMed:21325275, PubMed:24794869).  Forms the spike at the tip of the elongating tube formed by haemolysin co-regulated protein 1/Hcp1 (PubMed:26894531).  Allows the delivery of the Tse6 toxin to target cells where it exerts its toxicity (PubMed:30177742).
What are the official names of this protein?
Type VI secretion system spike protein VgrG1a, T6SS spike protein VgrG1a.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGA_WIGBR
Sequence: MSLTIQDLILKLKLFWEKQGCAILQPLDMEVGAGTSHPMTCLRAIGPEPIFISYIQPSRRFSDGRYGKNPNRLQHYYQFQVIMKPSPINIQDIYLISLQEIGININNNDIKFIEDDWENDTLGAWGVGWEVWINGMEVTQFTYFQQMGGLNCFPITGEITYGIERIAMKLQNIDNVYDLIWSNNFFQKITYKEMFYQNEIQQSVYNFEHSNIEFLLFCFKQYEKEAIKLINLKNPLFIPAYEKLLKAIYNFNLLDARKAISLTAKKNYTIRLRSLTNEISKLYLNYRKSLGFPMCKNNESIS
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_ACET2
Sequence: MKAKDIRKKSQEELQKELVELKAELFKLRFQHATNQLENPMKLRDVKKSIARIKTVLRERELKGIEV
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RNF5_MOUSE
Sequence: MAAAEEEDGGPEGPNRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRGAGVDLGQGHPASSWQDSLFLFLAIFFFFWLLSI
What is the function of this protein?
Membrane-bound E3 ubiquitin-protein ligase that mediates ubiquitination of target proteins (PubMed:23093945).  May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4 (By similarity).  Mediates ubiquitination of PXN/paxillin,thereby regulating cell motility and localization of PXN/paxillin (By similarity).  Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N (By similarity).  Mediates the 'Lys-48'-linked polyubiquitination of STING1 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses (By similarity).  Catalyzes ubiquitination and subsequent degradation of ATG4B, thereby inhibiting autophagy (PubMed:23093945).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF5, RING finger protein 5.
What is the protein family that this protein belongs to?
Belongs to the RNF5 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles.
Protein: RECR_LISIN
Sequence: MHYPEPITKLMDSFMKLPGIGPKSAARLAFYVLDMKEDDVLDFAKALVDAKRNLSFCSVCGHITDKDPCYICSDTSRDRSVLCVVQESKDVIAMEKMRDFHGLYHVLHGTISPMDGIGPEDINIPDLLKRLQDDTIEEVILATNPNVEGEATAMYISRLLRPSGIKVTRIAHGLPVGGDLEYADEVTLSKAMEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HIC2_DANRE
Sequence: MELPNHAKQLLLQLNQQRAKGYLCDVIIVVENALFRAHKNILAASSIYFKSLILHDNLINLDTDMVNPSVFRQVLDFIYTGKLLSSDQFSDHNFNALLTAASYLQLHDLAALCRKKLKRNGRSLLNKPTTPTNGRTSRNQRLSSTPVTPNQMSGLKDSEKTKRHEELIKDDLSEDEMFARNTHCTTSNSLSPSTSKNGSNGSCGMQELGLDLSKKSPSGSTATEEVSPSSIPQESPQSASESTANSASFDENPNTQNLTAGEPMELGVGECEESQPPPDVDQHKSSRQVTRQRRQPKSEGKKGEDMERVTLPNGVSKRLKVAGERLPAGGNGNSEVSFQCKDEEEGLENGQEQSEESGQSENEGGRNSANYVYRQEGFEPALGDNLYVCIPCGKGFPSSEELNAHVETHTEEELYIKEEDDDSYPKEDEVEAEDLSSQITQVHGTETRRFSCSVCNKSYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACEECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Hypermethylated in cancer 2 protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: IFNW1_HORSE
Sequence: MAFSVSSLMALVVISSSPVSSMSCDLPASLDLRKQETLRVLHQMETISPPSCLKHRTDFRFPQEQLDGRQFPEAQATSVLQEMLQQIVSLFHTERSSAAWNTTLLDRLLAGLHQQLEDLNTCLDEQTGEEESALGTVGPTLAVKRYFRRIRLYLTEKKYSDCAWEIVRVDIMRSFSSSANLQGRLGMKDGDLGSP
What are the official names of this protein?
Interferon omega-1, Interferon alpha-II-1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSD_ECOLI
Sequence: MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEKMFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIAISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAPTSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPHVKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADVMTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV
What is the function of this protein?
Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs).  KdsD is not essential in the KDO biosynthesis and can be substituted by GutQ.  Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P).
What are the official names of this protein?
Arabinose 5-phosphate isomerase KdsD, API, L-API.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: 033R_FRG3G
Sequence: MSGIQLDKETILKYSSAALVALSAVVAVMMVSNNSESWKPILVGAVVAASGAAAYQSWWPKQS
What are the official names of this protein?
Transmembrane protein 033R.
Protein: PAM17_DEBHA
Sequence: MLKNIGIYNRSINTIGRSVRFNSSGKSSLNWVEYLNLKKQNNRLNVASSAFTSLAGAFITLTYLGNIEIQVDKPIMGLDPFMVMGGAVILGGGVGYLFGPFIGTALFSLKNKAAMHQFKIKDQIFLQKIKHHRVDPSSQSFSNPVPDYYGERIYSLNNYKQWLRDCNAFRRKAKEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GUX2_HYPJE
Sequence: MIVGILTTLATLATLAASVPLEERQACSSVWGQCGGQNWSGPTCCASGSTCVYSNDYYSQCLPGAASSSSSTRAASTTSRVSPTTSRSSSATPPPGSTTTRVPPVGSGTATYSGNPFVGVTPWANAYYASEVSSLAIPSLTGAMATAAAAVAKVPSFMWLDTLDKTPLMEQTLADIRTANKNGGNYAGQFVVYDLPDRDCAALASNGEYSIADGGVAKYKNYIDTIRQIVVEYSDIRTLLVIEPDSLANLVTNLGTPKCANAQSAYLECINYAVTQLNLPNVAMYLDAGHAGWLGWPANQDPAAQLFANVYKNASSPRALRGLATNVANYNGWNITSPPSYTQGNAVYNEKLYIHAIGPLLANHGWSNAFFITDQGRSGKQPTGQQQWGDWCNVIGTGFGIRPSANTGDSLLDSFVWVKPGGECDGTSDSSAPRFDSHCALPDALQPAPQAGAWFQAYFVQLLTNANPSFL
What is the function of this protein?
Exocellobiohydrolases (CBH) that catalyzes the hydrolysis of 1,4-beta-D-glucosidic bonds in cellulose to release the disaccharide cellobiose (Ref. 3).  The degradation of cellulose involves an interplay between different cellulolytic enzymes.  Hydrolysis starts with endoglucanases (EGs), which cut internal beta-1,4-glucosidic bonds in cellulose to reduce the polymerization degree of the substrate and create new chain ends for exocellobiohydrolases (CBHs).  The CBHs release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain.  Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units (Probable).
What are the official names of this protein?
Exoglucanase 2, 1,4-beta-cellobiohydrolase, Cellobiohydrolase 6A, Cel6A, Exocellobiohydrolase II, CBHII, Exoglucanase II.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PQQB_PSEA7
Sequence: MHIRILGSAAGGGFPQWNCNCRNCRGVRDGSVAAQPRTQSSIALSDDGERWILCNASPDIRVQIAAFPALQPARRPRDTAIGAIVLLDSQIDHTTGLLSLREGCPHEVWCTQMVHQDLSEGFPLFRMLSHWNGGLRHRPIALDGEPFAIPACPRLRFTAIPLRSSAPPYSPHRGDPHPGDNIGLFVEDLDSAGTLFYAPGLGEVDEALLEWMRRADCLLVDGTLWRDDEMLACEVGDKLGRQMGHLAQSGPGGMLEVLAKVPAARKVLIHINNTNPILDTASAERAELDASGIEVAWDGMHIQL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: YDG1_ARATH
Sequence: MSQKRSLVFAIRDFPPGCGTHIDVSSSLNHPAEKAFKHPRTGDVSGENLSFAEAKPEGTCLKRESADQDHIFAAPEHNAKREPAGQDHVVAATTVAYATSSHRQKVEIGNSDCDPTPREKVLEVLSLFKQVYNQLDRDKKARRGGDFLDATSRIDLKTLTVLEKMGKQVNTEKRIGSVPGINIGDVFQYKTELRVVGLHSKPMCGIDYIKLGDDRITTSIVASEGYGYNDTYNSGVMVYTGEGGNVINKQKKTEDQKLVKGNLALATSMRQKSQVRVIRGEERLDRKGKRYVYDGLYMVEEYWVERDVRGKSVYKFKLCRIPGQLPLT
What are the official names of this protein?
YDG domain-containing protein At5g47150.
What are the subcellular locations of this protein?
Nucleus.
Protein: TBKB1_MOUSE
Sequence: MESMFEDDISILTQEALGPSEVWLDGPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLITDFGEEHGFPLYELKDGSLLEVEKVSLQQRLNQFQHELQKSKEQEEQLGEMIQAYEKLCVEKSDLETELGEMRALVETHLRQICGLEKQLQQQQGLRDAAFSSLSPPAVPASACPDLDLHYLALRGGPALGHAGWPGPTSVSVSELERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSECDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARNAGQRHSPLSQRHSPAPACPSPSPPARPPPCAPCQSPAAQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPGERTLAERVYAKPPSHHAKAGFQGRRSYSELAEGAAYAGASPAWLQAEAATLPKPRAYGGELYGRPLSPRRAFEGIRLRFEKQPSEEEEWAMPASPPSPEAGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
What is the function of this protein?
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.  Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus.
What are the official names of this protein?
TANK-binding kinase 1-binding protein 1, TBK1-binding protein 1, Similar to NAP1 TBK1 adapter.
Protein: PGK_PSEAE
Sequence: MTVLKMTDLDLKGKRVLIREDLNVPVKDGQVQSDARIKAALPTLKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVAEYLSKALGREVPLLADYLDGVEVKAGDLVLFENVRFNKGEKKNADELAQKYAALCDVFVMDAFGTAHRAEGSTHGVARFAKVAAAGPLLAAELDALGKALGNPARPMAAIVAGSKVSTKLDVLNSLAGICDQLIVGGGIANTFLAAAGHKVGKSLYEADLVETAKAIAAKVKVPLPVDVVVAKEFAESAVATVKAIAEVADDDMILDIGPQTAAQFAELLKTSKTILWNGPVGVFEFDQFGEGTRTLANAIADSAAFSIAGGGDTLAAIDKYGIAERISYISTGGGAFLEFVEGKVLPAVEILEQRAKG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.