PharMolix/UniProtQA huggingface dataset:
Protein: KATL1_RABIT
Sequence: MNLAEICDNAKKGREYALLGNYDSSMVYYQGVIQQIQRHCQSIRDPAVKGKWQQVRQELLEEYEQVKSIVSTLESFKIEKPPDFPVSCQDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKEMAGVGARGPVGRAHPISKSEKPSASRDKDCRARGRDDKGRKNMQDGASDGEIPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLVQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDIRLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGLSPEEIRALSKEELQMPVTRGDFELALKKIAKSVSAADLEKYEKWMVEFGSA
What is the function of this protein?
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility.  Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).  Has microtubule-severing activity in vitro (By similarity).
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A-like 1, Katanin p60 subunit A-like 1, p60 katanin-like 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (By similarity).
Protein: PTXBC_STAS1
Sequence: MTKEQILAEHIIDAVGGIDNMDNIINCMTRVRIKVLDEDKIDYEQLKSIKGVMGVVKDDRVQVVVGPGTVNKVASHMSELSGAPLGETIKHKSKDYRANAEAQAQANKSEFQSKQKRGKFNKLLKTIANIFIPLIPAFIGAGLIGGIAAVLSNLLAAGQISGEWVTQLVTVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGLTDKNMITNIFTGEPLQPGQGGIIGVIFAVWLLSIIEKRLHKIVPNSIDIIVTPTITLFIIGLLTIFIFMPLAGFVSDGLVTVINGIIDIGGVFSGFIIGAFFLPLVMLGLHHMFTPIHIEMINQTGATYLLPIAAMAGAGQVGAALALWVRCRKNTTLRDTLKGALPVGFLGIGEPLIYGVTLPLGKPFITACIGGGIGGAVIGGIGHIGATAIGPSGISLLPLISDHMYLGYIAGLLVAYAGGFIFTYFFGTTKAMRESDTLGD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in the uptake and phosphorylation of MurNAc-GlcNAc, the principle peptidoglycan turnover product of S. aureus, yielding cytoplasmic MurNAc 6P-GlcNAc.
What are the official names of this protein?
PTS system MurNAc-GlcNAc-specific EIIBC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S10A3_HUMAN
Sequence: MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ
What is the function of this protein?
Binds both calcium and zinc.  May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
What are the official names of this protein?
Protein S100-A3, Protein S-100E, S100 calcium-binding protein A3.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP3_DICDI
Sequence: MTKRILNVAEKPSAAKEIAAILSNKRATVREGFSKYNKLWDFKYNILNFNDCEMTFTSVTGHLMEIDVVEQFKPWASCDPIQLFDAPIRKTVPSDKEPLKKTLEREIKKADILILWLDCDREGENIAFEVLEVCKNAKKKFEFYRAHFSAIIPREIDRACKNLAKPNEKDSIAVDTRMEIDLRIGAAFTRFQTLYLKKFKIISNSDNQPKTTTPANGNILNNSNNNSSGKEIISYGPCQFPTLGFVVERYFRIVNFKPEDFWHLSVVHEKMDTSSGKMIPVTFSWCRNRLFDYTAAFILYEKCLDNTEATVVDVTSKESRYRPVPLTTIELQKAASKKLRISSVQTMQYAEELYTKGLISYPRTETDSFQAGTDLKGLIGNQASNPEWGAYASRLINNNQFVYPKSGKNNDNSHPPIHPTSSATGLSGNLKKIYDFITRRFLACCSEESVFANTTVTIDIQGERFSETGTMVLKLGYLEVYPFDKRNDKLIPTYQKGERFTPKRIDLTKGTTVAPHYITEAELLTAMDNNKIGTDATMATHIQTIQDRFYVKKNESNQFVPSNLGVSLVASYELMGFEFSKPNLRAAIEADVDKISRGQKTKQEVLLSTIEKYKQLYQLANQNINCFDRSFREYYEPADPKGGEFRVLVSQFSRCGKCNGKMQYKSDQNPEAPKRILFCPQCIDTFDLPKNGDISQLVTSMGVPQNCPICQYQVLSVRNPINDKSYTICPKCRNSPPDPIHKKPFHCFQCTFNCNLATGNKQQQQQQQQQQQQTNYNRNNNNNNTNSARPITTRTTRTTTQHRTFTASNNNFNNNNRNSDRNNNNFIF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: RK18_CYAM1
Sequence: MLMNRFVLKRVRQGKPLNKPRLSIFCSHKHIYAQIIDDMVGRTLVSASTYHYKQGWHSTMKDAQEVGQKLAQQALEKGIQQVVLDRGSYRYHGKIRALAEAARKEGLKI
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MP30_DICDI
Sequence: MDNLQTYKLRLLDKYVLNKCMSLNRSNTSTIALDHVNIKMNYRKKKKEVYQMIELITLFEQITGEKPLIKLNESTEKNNVVKLEDFKLAVRLHKQKAKYFLNALCYVGLGERKYLTLKEENNIDLAQLKLSYRYKNLKIFRPILIRKDMNLEARLAIDIQYKTIGINNGQLTKYKFYLWKKNEFRITE
What are the official names of this protein?
Uncharacterized mitochondrial protein 30, ORF188.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: K1C14_CHICK
Sequence: MSTTVRQFSSSTSLKGLGGGSSRLSCGRAAGYQAPSVHGGSSSYSVSSRIVSGLGAGYGGGYCSSVGGGLGGGFGASYGAGYGAGFGGGFGAGFGGGFGGGDGILPAGEKETMQNLNDRLAAYLDKVRALEEANTDLEVKIREWYKKQGPGPERDYSPYYRTIEELRSKILAATVENANIVLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLSRADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEISVEMDAAPGIDLTKILAEMREQYESLAEKNRRDAEQWFFSKTEELNREVAVNTEQLQSGKTEITELRRTIQSLEIDLQSQLSTKAALEGTLADTEARYGTQLAQLQALITSVEEQLAELRCDMERQNHEYRVLLDVKCRLEQEIATYRRLLEGEDAHISSQYSSAMSSHSGRDAITTSRQVRTIVEEVQDGKVVSSREQMALTTR
What is the function of this protein?
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
What are the official names of this protein?
Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.
Protein: WHIA_BACP2
Sequence: MSFASETKKELTNLDVKDCCTKAELSALIRMNGSLSFSNRKLILDIQTENAAIARRIYTLLKKKYDVTVELLVRKKMRLKKNNVYIVRLVERAKTILEDLKILGEQFVFERNISEELVKKRCCKRSYMRGAFLAGGSVNNPETSSYHLEIFSLYKEHNDALCELMNQFHLNSKTLERKKGYITYMKEAEKITEFLSVVGAHNSLLRFEDVRIVRDMRNSVNRLVNCETANLNKTIGASLRQVENIQFIDEKIGLDALPDKLREIAKLRVDYQEVTLKELGEMVESGKISKSGINHRLRKLDQIAEQLRNGQAVTLK
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: QCR1_HUMAN
Sequence: MAASVVCRAATAGAQVLLRARRSPALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVANKLCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCTSATESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVREICSKYIYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity).  The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties (By similarity).  May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (Probable).  Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons (PubMed:33141179).
What are the official names of this protein?
Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CP1A3_ONCMY
Sequence: MVLMILPIIGSVSASEGLVAMVTLCLVYMIMKYMHTEIPEGLKRLPGPKPLPIIGNMLEVHNNPHLSLTAMSERYGSVFQIQIGMRPVVVLSGNETVRQALIKQGEDFAGRSDLYSFKFINDGKSLAFSTDKAGVWRARRKLAMSALRSFATLEGTTPEYSCALEEHVLKEGEYLVKQLTSVMDVSGSFDPFRHIVVSVANVICGMCFGRRYSHDDQELLGLVNMSDEFGQVVGSGNPADFIPILRYLPNRTMKRFMDINDRFNNFVQKIVSEHYESYDKDNIRDITDSLIDHCEDRKLDENANIQVSDEKIVGIVNDLFGAGFDTISTALSWAVVYLVAYPETQERLHQELKEKVGMIRTPRLSDKINLPLLEAFILEIFRHSSFLPFTIPHCTIKDTSLNGYFIPKDTCVFINQWQVNHDPELWKEPSSFNPDRFLSADGTELNKLEGEKVLVFGMGKRRCIGEAIGRNEVYLFLAILLQRLRFQEKPGHPLDMTPEYGLTMKHKRCQLKASMRPWGQEE
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A3, CYP1A3, CYP1A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PSB1_DROME
Sequence: MSRLGFEQFPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-1, Proteasome 26 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: B3GN6_HUMAN
Sequence: MAFPCRRSLTAKTLACLLVGVSFLALQQWFLQAPRSPREERSPQEETPEGPTDAPAADEPPSELVPGPPCVANASANATADFEQLPARIQDFLRYRHCRHFPLLWDAPAKCAGGRGVFLLLAVKSAPEHYERRELIRRTWGQERSYGGRPVRRLFLLGTPGPEDEARAERLAELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLLSGDDDVFVHTANVVRFLQAQPPGRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVYCSGGGFLLSGPTARALRAAARHTPLFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGAQQSSFDPCMYRELLLVHRFAPYEMLLMWKALHSPALSCDRGHRVS
What is the function of this protein?
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins.  Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
What are the official names of this protein?
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase, Core 3 synthase, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6, BGnT-6, Beta-1,3-Gn-T6, Beta-1,3-N-acetylglucosaminyltransferase 6, Beta3Gn-T6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: UBE2Z_RAT
Sequence: MAESPTEEAATATAGAGAAGPGASGVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNENAEMDSDSSSSGTETDLHGSLRV
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Specific substrate for UBA6, not charged with ubiquitin by UBE1.  May be involved in apoptosis regulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 Z, E2 ubiquitin-conjugating enzyme Z, Uba6-specific E2 conjugating enzyme 1, Use1, Ubiquitin carrier protein Z, Ubiquitin-protein ligase Z.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RK22_BRADI
Sequence: MTSFKLVKYIPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKAQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANAAHYRDFDKANLFITKAEVSRSTIMKKFRPRARGRSFPIKKSMCHITIALNIVKRSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: P2C35_ARATH
Sequence: MGCVQCKCCSRYPSSSSDGDSRGPLEANGVLKGKDQKPLGSIHVPSPNFDMVYSVLSQRGYYPDSPDKENQDTYCIKTELQGNPNVHFFGVFDGHGVLGTQCSNFVKERVVEMLSEDPTLLEDPEKAYKSAFLRVNEELHDSEIDDSMSGTTAITVLVVGDKIYVANVGDSRAVLAVKDRNRILAEDLSYDQTPFRKDECERVKACGARVLSVDQVEGLKDPNIQTWANEESEGGDPPRLWVQNGMYPGTAFTRSVGDFTAESIGVIAEPEVSMVHLSPNHLFFVVASDGIFEFLPSQAVVDMVGRYADPRDGCAAAAAESYKLWLEHENRTDDITIIIVQIKKLSNE
What are the official names of this protein?
Probable protein phosphatase 2C 35, AtPP2C35.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RL10_ACIAD
Sequence: MALLIEDKKQIVAEVSEIASTAFAAVVADYQGLTVEQLTTLRVEARKLGVATRVVRNTLAKRALQDTPFSILNDDLVGPTILAFSTSEDDMGAAARLFEEFAKTNKVFELKAAAFEGKLYQGADVSVIANLPNQEKALTMLASVLQAPVSKLGRLITALKEKNESEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YGHO_ECOLI
Sequence: MMNPVLWLQMTNMISYQGLVRTFLNKNDLKAFIAFPSSLYPDDPNWIPPLFIERNEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGKDTGHFGMIDAIDDPQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYAAHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQILREIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNINEAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEALRDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI
What are the official names of this protein?
Protein YghO.
Protein: OL143_ARAHY
Sequence: MATATDRAPHQVQVHTPTTQRVDVPRRGYDVSGGGIKTLLPERGPSTSQIIAVLVGVPTGGTLLLLSGLSLLGTIIGLAIATPVFIFFSPVIVPAVVTIGLAVTGILTAGACGLTGLMSLSWMINFIRQVHGTTVPDQLDSVKRRMADMADYVGQKTKDAGQEIQTKAQDVKRSSS
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin Ara h 14.0103, Oleosin 5.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: SYK_BURO1
Sequence: MTEPTQTQPAVTADENQIIAERREKLRALREQGVAYPNDFRPEHHAADLQAKFADSDKAALEANPVEVSVAGRMMLKRVMGKASFATVQDGSGQIQFFVTPNDVGADTYDAFKKWDLGDIVAARGVLFRTNKGELSVQCKELRLLSKALRPLPDKFHGLSDQEMRYRQRYVDLIVTPETRDTFRARTKTIASIRKFMDNADFMEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLAKPFHRLTITQAIQKYAPDYTDGQLSDDAFLRTELKRFGVDVSQPAFLNAGIGALQLALFEETAEAQLWEPTFIIDYPVEVSPLARASDTVPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGIGIDRLVMLLTDSPTIRDVLLFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: RNP4_SULIL
Sequence: MRIKNKIKKRIIELIELAYITARKGDLELAREYIKLAEMYSRKGRIKIPLKYKRMFCRKCYTPLITGVTERRRIRSKILIRTCLICNWQRRYVLSRNKGSNKEN
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_ACHLI
Sequence: MQFQTIAAIATPLGTAGISVIRVSGDEAISKVNQIFKGKNLNKVKSHTIHYGHILNEDGSILDEVMISVFIAPKSFTKEDVVEISTHGGILITQKVLERILETGIELAQPGEFSKRAFLNGRIDLVQAEAIMDIIHATNENAIKVANKALNKATSSMIDNLKSKVLTLIAQIEVNIDYPEYDDAIIMSKELIYPRVNDLLDEINDILTKSKRTQYIREGVKTVIVGRPNVGKSSLLNALLNEERAIVSDIAGTTRDTIDAFVNLDGVTLQLIDTAGIRDALDTIEKIGVDRSRKAIHEAELVLLVLDLSQKLTKEDEMLLTLTEHKNRIIIGNKKDLPSYLEIDTNVQISTLEKEGLSVLESEILKTLKLDNLVDKDFNYLSNVRHIQKLKEAKTSLESVINAIHHDMPVDIYAVDLTTAWNRLGEILGNHQYGDLLTELFSKFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V243_FOWPN
Sequence: MFDRTWHISRFLLEYGADVNIKNRYGSTPLFEAICNCSCKNVKLFLENNADINEVDLDGDATLMKIFNYNCRIHSGLNSVHLRIARIVIPYLKVIGLKNKHVKNVHAYKQNINFFNSVKQLRLISDESDREINRMKNTILRKNKFGNDITMYDILLEKNMNQLVQIIKNPLIKKRCSELILFKRIVKNNIIYIENRYQKIHGANTVIEFYQYEYTDKWMILPQEIKINILCYLDNKELDYIYESSLENNKNNTSDKKYDVCC
What are the official names of this protein?
Putative ankyrin repeat protein FPV243.
Protein: KBRS2_CHICK
Sequence: MGKSCKVVVCGQAAVGKTAILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGLRDGLELPKHCFSCTDGYVLVYSTDSKESFRRVELLKKEIDKCKDKKEVTIVVLGNKCDLQEQRRVDHDAAQHWAKGEKVKLWEVSVADRRTLIEPFIYLASKMTQPQSKSAFPLSRKNKGSGSVDG
What is the function of this protein?
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.
What are the official names of this protein?
NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP1_TRIEQ
Sequence: SLPLHVLAHPQPSTSTSLAGRAGAVDLNEFRVAHRSSYASHDEMKKLPSIASFRQGTYLEVATELVKQTMPNMEFRLVDDHYVGDSGIGHVRFRQTMHGIDIDNSDFNVNVGKDGKILSHGNSFYTGPAPASNPMIKRDFIDPMQALNGVRKALNLPVKADGAHVENMSEHKVMFKGTSGALSDPTAKLCYMAKEDGSLALTWRVETDIGDNWLLSYMDAKESSKVHNVVDYVAHATFQVYKWGLADPTEGKRDILTNPWNLKTSPLTWLADGKTNFTATRGNNAIAQYNPDGGNDYENNYRPSPKNLKFEYPYSPDMNPPKTYIDASVTQLFYTSNVCHDLYYMLGFNEKAGNFQVNNRGQGGKGNDYVILNAQDGSGTNNANFATPPDGQPGRMRAYIWTRANPPRDASFEAGTIIHEYTHGLSNRLCGGPANSRCLNALESGGMGEGWGDFYATAVRLKPNDTRKTNYVKGGWVNNSPKGVRMYPYSTDMNVNPLVYTSNNKLNEVHAIGTVWCTMLYEVLWNLIDKHGKNDGPVPVFENGVPNDGKYLAMKLVMDGMAIQPCNPNFVQARDAILDADMNLTKGANKCEIWKGFAKRGLGVGAKFDPKNRTG
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 1, Fungalysin MEP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_AGRVS
Sequence: MSLKIRLARGGSKKRPYYQIVIADARSPRDGRFLEKVGSWNPMLGKDNEKRVELNADRIKEWIAKGAQPTDRVLKFLAEAGLAERAARSNPEKAKPGKRAVERLAEKKQKADALAAATAEAAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL2_RUTMC
Sequence: MAQVIKRKPTSPGRRFVVSIVDKELHKGASYAPLTQSKNRISGRNNVGRITTRHKGGGHKRRYRIIDFKRNKDDITARVERLEYDPNRSANIALVLYTDGERRYIIAPHGLSVGYTIVSGNSVAIQAGNVMPLSNIPLGGVVHCIELKPMKGAQIARSAGAFAQLIAKEGNYVTLRLRSGEVRKVLADCRATIGEVSRSEHSLKKLGKAGATRWRGVRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGTPTKGYKTRSNKRTDKLILRHRNKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS11_PELTS
Sequence: MARRVTRAKKRERKNIVSGVAHIKSTFNNTIVTITDTKGNTISWSSAGQVGFKGSRKSTPFAAQMAAESAAREAMEHGLKEVEVMVKGPGAGREAAIRSLQAAGLEVNLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.