PharMolix/UniProtQA huggingface dataset:
Protein: GCH1_STRPQ
Sequence: MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSVCEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: O16B_CONVX
Sequence: MNLACVLIVAVLFLTASQLATAASYARDKQEYPAVRSSDEMQDSEDLTLTKECTDDSQFCDPNDHDCCSGECIDEGGRGVCAIVPEHV
What is the function of this protein?
May act as a neurotoxin, but produces no obvious effect on ionic currents when tested on the mouse dorsal rooted ganglia (DRG).
What are the official names of this protein?
Conotoxin VxVIB, Conotoxin vx6b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_SALEP
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: TRMD_HELPY
Sequence: MKFSVLTLFPQLVWPYFEDSILKRALEKNLFELEVLNLRDFSANKYQKADHTLIGGGAGQILDPEMVENALHSVKNPKHTIFLSAVGKPFKQTDAMRLAQKKHVVLVCGRYEGFDERSIELGADEVFCIGDFILTGGELGALCLIDSIARHIQGVLGNAQSLENESFENHYLEAPNFANAVFKSKEINKIPAPLEYSKGNHAKIKQLKLDLSKLRTKFYRLDLFKQHKS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACA_STAA2
Sequence: MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: Y4094_CROS8
Sequence: MAARHRAGKTIVKMDNGPREKLMRYGAADLSDEELLAIFLRTGTPGMDVMTLAKRLLAHFGSLYGLLSADIRPFRDIGGVGMAKYAQLKAIGELARRYYRSRPCEETALLSPTITRDFLESQLAEQEREVFLVIFLDSQNRIIRQNTLFTGTLSHVEVHPREIVREAVRLNAAGIILAHNHPSGRAEPSRADKMVTERIVKSCQLVDIRVLDHLVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein ESA_04094.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: PDXA_THEVB
Sequence: MSLALTLGDPAGIGPEILLKALAHLPSELLGQFFIAGTGQVLEETYARLCQQGQVAIDPAQLQLWEHPLDEVIVPGRPSVASGTASFAYLKTAIQRAIAGEVAGIVTAPISKACWQAAGYSFPGQTEVLAHLTGTAHVGMLFLGRSPVTHWVLTTLLATTHIPLQAVPRALTPEGLNEKLALLIQFLRERRHLERPRIAIAGLNPHSGEQGHLGQEEVTWLIPWLAAAQQQYPEVELIGPVPPDTLWIGAADAWWGRPAPATAYDAYLALYHDQGLIPVKMLAFREAVNTTIGLPFIRTSPDHGTAFDIAGTGVADPQSFLAAIAWAQTLSKGSVFPLTLA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MZM1_TALSN
Sequence: MTTPSVSAISAYRQLLRATRIAFKDDYRVLLAARTEARKQFDQHKRTAVDTPMQIQHALETASILRHNIVQGARDAEKEDAKWELRIHDDIERGDNDSVKIGGKKVKIEKACS
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MYP0_HUMAN
Sequence: MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK
What is the function of this protein?
Is an adhesion molecule necessary for normal myelination in the peripheral nervous system.  It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
What are the official names of this protein?
Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero.
What is the protein family that this protein belongs to?
Belongs to the myelin P0 protein family.
Protein: ELAP2_XENLA
Sequence: MGVFCWSGCLVISLQLLLGAALDNLSTCKEEDYHYEYTECDSTGSRWRVAVPNPGKACAGLPDPVKGKECTFSCAAGEFLEISSQLCSKCEPGTYSLGTGIKFDEWDKMPQGFSNVATYMENTAEFSDNKPDSCVNSSWIPRGNYIESNSDDCTVSLIYAVHLKKAGSVSFEYQYLDNNIFFEFFIQNDQCQEMSSSSDKWVKLSDNSDWMNHMVSLKSGTNILYWRTTGILMGTKVAKPVLIKNITIEGVAYTSECFPCKPGTYSDEAGSSSCKICPRNTYSDRQAKECIKCFEEKEYSEEGASKCEERPPCTKKDLFQIHTPCDSERKTQVIYKWIEPKICREELPASIKLPASGNKEDCPPCNPGYFSNGTSACSPCPVGTYSNGLSECKTCPAGTEPVLGFEYKWWNILPGNMKTSCFNVGNSKCDGMNGWEVAGDHIQSGIGGTDNDYLILNLHISGFKPPTSVTGATGAELGRVTFVFENICVSDCVLYFMVDINRKSTSLVESFAGRKVYQSYTHVIHKNATYMFTWAFQRTNLAQDSRRFVNDIAKIYSIMVTNAIDGVSSSCRACALGPQQLGSSCVPCPAGHYIDKESNMCKECPPNTYLTPHQVYGKEACVPCGPGSKSNKDHSACYSECLVTYTNENQTLSYNFNNLGKVATLLNGPSFTSKGTKYYHLFNMSLCGHGGEKMAVCTDNITDVTGKDIEADSDDYSNVVKTFVCQSTIIPSDSKGFRTALSSQSVNLADSFLGVTNNSSLRGITISPDIFPSHLKIPDVNFFFKSLATTSSCEQGRATVISMRCNPAKLGQGDISVPRNCPAATCDGCNFYFLWETAEACPLCMESDYQKIEGACKHGQQETHYVWNEMKLCTNGVSLPEKNVSACESIDFWLKVGAGVGAFTAVLLIALTCYFWKKNQKLEYKYSKLVITANSKECELPAPDSCAIMEGEDNEDDVIYSNKQSLLEKLKSLATKEKEHNFESVQLKSSRAQNI
What is the function of this protein?
Functions as a regulator of the BMP signaling pathway and is involved in epidermal differentiation.
What are the official names of this protein?
Endosome/lysosome-associated apoptosis and autophagy regulator family member 2, Estrogen-induced gene 121-like protein, xEIG121L.
What is the protein family that this protein belongs to?
Belongs to the ELAPOR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPG_STAA1
Sequence: MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTPYMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITDIEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLYSEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSVILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQITEIVGGSAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DEOB_SHEPC
Sequence: MKRTIIMMLDSFGVGASADAASFGDVGSDTFGHIAKACAEGKADIGREGPLKLPNLARLGLGHAAMESTGAFAPGFGDNVELIGAYGHAQELSSGKDTPSGHWEMAGVPVLFEWGYFSEHQNSFPKELTDKILARAGLDGFLGNCHASGTTILEELGEEHMRSGKPIFYTSADSVFQIACHEETFGLDNLYRLCEITREELAPYNIGRVIARPFNGTGQSDFARTGNRKDYSLEPPAKTVLDKLKAAGGEVVSVGKIADIYAYCGITKKVKANGLEDLFDATLAEVKSAGDNTIVFTNFVDFDSHYGHRRDVAGYAKGLEYFDARLPEMLALLGEDDLLILTADHGCDPTWQGTDHTREYVPVLAYGAGLKAGSLGRRNSFADIGQSIASHFKLEPMAYGESFI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_VARPS
Sequence: MQLNPAEISELIKSRIEGLGVSANIRNEGTVVSVTDGIVRVHGLSDAMQGEMLEFPPTADGTPSFGLALNLERDSVGAVILGEYEHISEGDTVKCTGRILEVPVGPELIGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPMQTGLKSIDSMVPIGRGQRELIIGDRQTGKTAVAIDAIINQKGQNMTCVYVAIGQKASSIKNVVRALEQAGAMDYTIVVAASASESAAMQYVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAINAGISVSRVGSSAQTKVIKGLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLPISLMGATLFAVNKGFMDDLEIKKVLPFEHGLHQFLKSSHAALLDKIEKAKALDKDAEAELTAAITSFKKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL29_BORHD
Sequence: MLKKFKDLTLEDMKARRLALRKEYMDLRFKAVVGHVENPLKKRELRRDIARLNTIIHEYAIGIRKV
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: AROC_ACAM1
Sequence: MGNTFGHLFRITTFGESHGGGVGVVIDGCPPQIEIAAEDIQFELDRRRPGQSRITTPRKETDTCEIVSGMFQGKTLGTPITILVRNKDTRPQDYSEMAQVYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILQQAAGVEVIGYVKRIKTVEADIDPDQVTLAQVEANMVRCPNPETAEEMIDLIDQTRRDANSIGGVVECVARQVPKGLGAPVFDKLEAELAKAVMSLPACKGFEIGSGFAGTQLTGLEHNDEFYTDETGRIRTVTNRSGGIQGGISNGENIVLRAAFKPTATIGKPQKTVNQAGEATTLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHAQCELLTE
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TOP6B_SULIL
Sequence: MSAKEKFTSLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKITIDLIDEARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSKYVNRQTRGMYGLGVKAAVLYSQMHQDKPIEIETSPANSKRIYTFKLKIDINKNEPIIVERGSVENTRGFHGTSVAISIPGDWPKAKSRIYEYIKRTYIITPYAEFIFKDPEGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIKILINNLKRDYTIKEFLVNEFQSIGDTTADKILELAGLKPNKKVKNLTEEEITRLVETFKKYEDFRSPSADSLSVIGEDLIELGLKKIFNPDFAASITRKPKAYQGHPFIVEAGVAFGGSIPVGEEPIVLRYANKIPLIYDEKSDVIWKVVEELDWKRYGIESDQYQMVVMVHLCSTKIPYKSAGKESIAEVEDIEKEIKNALMEVARKLKQYLSEKRKEQEAKKKLLAYLKYIPEVSRSLATFLASGNKELVSKYQNEISEGLFKLISKKLDLINIEEYRKVYRVDSE
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: RSSA_ZYGRC
Sequence: MSLPATFDLTTEDAQLLLAANTHLGARNVQVHQEPYVFKTRPDGVNVVDVGKTWEKLVLAARIIAAIPNPEDIVAISSRTFGQRAVLKFSAHTGATPIAGRFTPGSFTNYITRSFKEPRLIIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEYVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSVMPDLYFYRNPEEIEQQVAEETAGAATEEEEAKEEVTEEQTEATEWAEETTEAVAW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CHLL3
Sequence: MPLHKSAEKRLRQSERRNARNRARKKELKTLIKNMQKLIEARAAKSEVESAYRSAVQKLDRLGVKSYIHANKASRKKSQLTRLFNGYAEAE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TRPC_PHYPR
Sequence: MGNILEEIAAQRRLDVAAAKQVVSTDDLAKKIEHTESVYGPALPVLERLNAPAEQVQAYANAGASMISVLTEPKWFKGSLDDMMEAREVVEGMSQRPAILRKDFIIDVYQLLEARAYGADCVLLIVTLLSKEQLIELIDATHNLGMCALVEVNSVQELDIALAAKARLIGVNNRDLRTFKVDMNTTARVADAIRERGLSLGRDGVALFALSGIRSHTDVVKYEKCGARGILVGEYLMKSGDIATTVKDLLQNVTRHSESGEFALLPPLAKVCGITTVEYALAALRNGANMIGIIMAEHSPRYVEKEEAKAIAKAVREYGERTGPILSDILESHLDDKSDWFHRNVLALREACSRAPLVVGVFVNKTATEMNAAAEEIGLDLVQLHGDEGFEICKDIKYPTIRALHLPDTAQCDGVDAEAVLQQVSEGLANYILLDTTVKGQQGGTGVAFDWKIAAIFTQARLPCLMAGGLTPENVVKALSVGHPVGVDVSSGVEVKGSPGVKDLDKVAAFLKAVKDHLSVATLKIDEETEN
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.
What are the official names of this protein?
Tryptophan biosynthesis protein TRP1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: NUSB_DELAS
Sequence: MSDEQSTPASGRPPRQSRGGLTSTGARKAASKSNRSRAREFALQALYQHLVGGNDVEAIDRFTRDLSGFHKADSVHYDALLRGCINSQVDLDALIAPKLDRTMAEISPIEHASMWIGVYEFQHCPDVPWRVVLNECIELAKEFGGTDGHKYVNAVLNGLAPTLRAAEVEHDRAGKGSAPAQPAAKADTATDAVADAATDAAAADDAADQAAG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: VG62_BPML5
Sequence: MKYGVRYPISGVHECPFGYKQAQMIQFLATRYGVYEAELVTSHDGLQWEAI
What are the official names of this protein?
Gene 62 protein, Gp62.
Protein: CTNL1_MOUSE
Sequence: MAASPVPGGGGAGAVHSSNAAGFTFDSGLEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIASLTDVTKRSHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADRVVIKQIVTSRNKILATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTASKTCLRHPSCESAHTNKEGVFDRMRVALEKVTEIVTDCRLSGETDSSSVSIFTGIKELKVNIEALRENVCFESKENLSAALEAVLEHVEDFTDSAYTSHEHRERILELSSQARTELQQLLSVWMQTQSRKTKSAAEELELTVLKISHSLDELRRELHCTAMQLAADLLKFHADHVVLKALKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQMSDMATLLREISDVFEGRRGERCDHLSLPKPTKNSANLKSLKPDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWEDEENEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFAAEGLKLTSSVQSFSKQLKDDDKLMLLLEINKLIPLCHQLQTITKTSLQSKVFLKVDKCITKIRSMMTLVVQLLSLCYKLLKKMENNRWGSATNKDTMDGQN
What is the function of this protein?
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
What are the official names of this protein?
Alpha-catulin, Alpha-catenin-related protein, ACRP, Catenin alpha-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.
Protein: 1FEH_BROPI
Sequence: MAQAWAFLLLPVLLLSSYASHRLFPSYITGPLCGSTTTSSSSSSGVRSFLCSQQDSQTPSPASTMYKTAFHFQPAKNWINDPSGPMYFNGFYHEFYQYNLNGPTFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGQPVIIYTGGDIEKHQAQNIAFPKNRSDPYLREWTKVINNPVLLPNEPGMNSIEFRDPTTGWIGPDGHWRMAVGAEWHGYSAALLYKSEDFLNWTMVDHPLYSHNGTNMWECPDFYAVLPGNNGGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLERDAFVPDVVLDDHRLWLRIDYGTFYASKSFYDSKKGRRVIWGWSRETDSPSDDLEKGWAGLHTIPRTIWLDGDGKQLLQWPVDEIESLRTNEINHQGLELNKGDLFEIKGVDTFQADVEIDFELPSLDDAEPFDPSWLLDPEMHCGEAGASVQGGIGPFGLVILASNDMNEHTEVYFRVYKSQEKGMVLMCSDLRRSSLRPGLETPAYGGFFELDLAKEKKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADGGSAHMYAFNNGNAIVKVPQLRAWTMRKAQVNVEMGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans.  Has low activity against beta-(2,6)-linked fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis.
What are the official names of this protein?
Fructan 1-exohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: FER4_USTMA
Sequence: MTASALAYLEPDSSAELTGVYHLVLDRPEARNAISRSLLQDVLQCLQVLVCKITQPKQDEPLPRVLILRANGPCFCAGADLKERREMSEAEVIEFLQDLRHMLEQVEKLPIPTLAAIDGPALGGGLELALACDFRIAAETVSKIGFPEVKLGIIPGAGGTQRAPRIIGMQRAKELIYTGTQLNATQAKDLGLIDHVAPGSTCLKLCQELAQQMMPSAPLALRAAKMAISMGANVELARGLDLEWACYEPLLESKDRREALDAFQQKRKPIFTGK
What is the function of this protein?
Enoyl-CoA isomerase/hydratase; part of the gene cluster that mediates the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence (PubMed:17138696, PubMed:20070524).  The first step of ferrichrome A biosynthesis is performed by the HMG-CoA synthase hcs1 which catalyzes the generation of HMG-CoA and CoA using acetoacetyl-CoA and acetyl-CoA as substrates (PubMed:20070524).  The enoyl-CoA isomerase/hydratase fer4 then catalyzes the conversion of hcs1-produced HMG-CoA to methylglutaconyl-CoA (PubMed:20070524).  The acyltransferase fer5 then fuses the fer4-generated methylglutaconyl-CoA with sid1-generated hydroxyornithine to yield methylglutaconyl hydroxyornithine (PubMed:20070524).  Methylglutaconyl hydroxyornithine is then available for use by the NRPS fer3 to generate ferrichrome A (PubMed:20070524).
What are the official names of this protein?
Enoyl-CoA isomerase/hydratase fer4, Fe-regulated protein 4, Ferrichrome A biosynthesis protein fer4.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: RSMH_BACAC
Sequence: MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDVVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVITFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_KATPE
Sequence: QPITESQRLFSIAVSRVQNLHLLAQRLFSDFESSLQTQEQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFPSRSLSGAQRNQISEKLSDLKMGIQLLIRANQDGAEMFADSSALQLAPYGNYYQSLGGDESLRRNYELLACFKKDMHKVETYLMVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP9_NEUCR
Sequence: MASTRVLASRLASQMAASAKVARPAVRVAQVSKRTIQTGSPLQTLKRTQMTSIVNATTRQAFQKRAYSSEIAQAMVEVSKNLGMGSAAIGLTGAGIGIGLVFAALLNGVARNPALRGQLFSYAILGFAFVEAIGLFDLMVALMAKFT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TXLNA_MOUSE
Sequence: MKNQDKKNGPAKHSNSKGSPGQREAGPEGAHGRPRQTAPGAEAEGSTSQAPGKTEGARAKAAQPGALCDVSEELSRQLEDILSTYCVDNNQGGPAEEGAQGEPTEPEDTEKSRTYAARNGEPEPGIPVVNGEKETSKGEPGTEEIRASDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKEFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLTAGGITDIGSERRPEATTASKEQGVESPGAQPASSPRATDAPCCSGAPSTGTAGQTGPGEPTPATA
What is the function of this protein?
May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
What are the official names of this protein?
Alpha-taxilin.
What is the protein family that this protein belongs to?
Belongs to the taxilin family.
Protein: URE2_MARMS
Sequence: MIPGEIQVAEGVIELNVGRKTVKIRVENTGDRPVQIGSHYHFYEVNPALSFDRELTKGFRLNIASGTAVRFEPGQGREVELVEYAGTKTIYGFRGEVMGKLVGAE
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.