PharMolix/UniProtQA huggingface dataset:
Protein: Y3849_PHOLL
Sequence: MLEIRNVTYAYGERVILQELNLQLKEKRIAIIGSNGCGKSTFARLLNGLLVPKNGDVLVDGLNTRTEGKAIRRKVGFVFQNPDNQIVFPVVEEDLAFGMKNLGFSKDTIRQRTQEALSRYDLLQFREHPAHLLSGGQKQLLAISGVLVMEPDYIIFDEPTTLLDLRNKRRVAAAIDNLSQTVIVVSHDLDFLAGFDRVLVFDDGRVVVDDIPSIAIPEYVRMML
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein plu3849.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLPC_CHLMU
Sequence: MSYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKNEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYVGTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELETFNLQLPPSSSITPRNTNSSSSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILCRRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKKYEEHHNVFITDEALVAAAKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYEKAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLMLENTLQKKVIGQDQAVASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQIAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRSHMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQMALNIPDSVVSFLVDKGHSPEMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLIEERVIFEREDEISALAVEGDGPASVTADES
What are the official names of this protein?
Probable ATP-dependent Clp protease ATP-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: UN45A_MOUSE
Sequence: MTVSGPETPEPRPSDPGASSAEQLRKEGNELFKCGDYEGALTAYTQALSLGATPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTEETDLMLAALRTLVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVIFDALKEGVKKGFRGKEGAIIVDPARELKVLINSLLELLTEVGVSGQGRDNALTLLIKMVPRKSPKDPNNSLTLWVIDQGLKKILEVGGSLQDAAGELTVTANSRMSASILLSKLFDDLKCDAERENFHRLCENYIRNWFEGHGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEREEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKGSERDSIRIRALVGLCKLGSAGGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVEDEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQHPKDKPSFVRARVKKLLAAGVVSAMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRGTVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSLLHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATECMCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPALCSRIPQVTTHWLEILQALLLSPNQELQHRGTVVVLNMMQSSKEIAGTLMESEVLEILSVLAKGEESPVTRAAAACLEKAVEYRLIQPNQDGE
What is the function of this protein?
May act as co-chaperone for HSP90 (Potential).  Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1.  Positive factor in promoting PGR function in the cell (By similarity).  May be necessary for proper folding of myosin (Potential).  Necessary for normal cell proliferation.  Necessary for normal myotube formation and myosin accumulation during muscle cell development.  May play a role in erythropoiesis in stroma cells in the spleen.
What are the official names of this protein?
Protein unc-45 homolog A, Unc-45A, Stromal membrane-associated protein 1, SMAP-1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus (By similarity).
Protein: Y732_LACH4
Sequence: MADDKKQLLIVTGMSGAGKTVVAHDLEDMGYFVVDNLPPTLLGSFWDYNSNDFHKVAVVIDLRVKTFYTDLLDEVNSLEDNGNVQATILFLDASDDVLVARYKETRRLPPLANNGKGRLLDGIQEERRILMPIKNRSNYIINTSNLSTKDLKQKLINTFSDRKRQPFSIEVMSFGFKYGMPIDADIVMDVRFLPNPFYIPELRPFTGLDKRVFDYVMNKKETQVFYQKLLDLLETAIPGYIKEGKEKLTIAIGCTGGQHRSVSIAQQLARDLSKKYPVDITHREVSRYIRK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein lhv_0732.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LPR5_ORYSJ
Sequence: MSPRIQQLAAVLLAAVVVVAAARDEPAAAKNYQTQWDTVMSILNCKSDSLIPSYICSVISKSRWGWASDDPNDDEYTPPDHPLPAPAAGRRRWPVMTSLNLTKYVDSLPRIAKIRGYGIRHGRPVPIKLTIGMYSKTWQFHRDMPPTPVFVYGQSLQTATFPGPTIVARQGVPLAVEWQNHLPDAHILPWDPKVPTAIPKKGGVPTVVHLHGGAHPPEFDGHAFAWFTRDFAENGSTWTRKTYTYPNVQAPGNLWYHDHALGLTRVSLLAGLLAAYVIEKPELEDPMNLPCGDHDLHLVIADREFYTNGSISIDREWKPEYFGLVITVNGKAWPYLSVQRRRYRLRILNASNARYFNVTLSNGALPFTVIGSDSSYLSRPVTVSNLVLSPAEIFDVIVDFSRLPAAMTEIEMLNTAPYPFPNGPNVTDPNLDGKVMLFKVAGKGKVDDMPDKSKVPEHGVPYASVAALPPPTTTRYIVLYENQTAPGNLYINGLRLEDPVTETPKSGTTELWQVINLTGDNHPLHLHIATFQAIKMTKIEGFQVFKDCMIKNNNTATCNLDQHAVGPVVPVPEEEKTWKNAVKIPPEFMTSVVVAFRLVEANQPYPFDATTEPGFVYHCHILDHEDNAMIRPLKLLP
What is the function of this protein?
Multicopper oxidase that may play a role in the maintenance of inorganic phosphate homeostasis.
What are the official names of this protein?
Multicopper oxidase LPR1 homolog 5, OsSTA2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RISB_PSEMY
Sequence: MTLKTIEGTFIAPKGKYALVVGRFNSFVVESLVSGAIDALVRHGVSESDITIIRAPGAFEIPLVTQKVAQRGEYAAIIALGAVIRGGTPHFEYVAGECTKGLAQVSMEYGVPVAFGVLTVDSIEQAIERSGTKAGNKGAEAALSALEMVSLLAQLEAK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MSHD_XYLCX
Sequence: MPVPLQIGPLGPSDVEGVRGLARAAETADGVAPLSEQPLLRLSSDEGWLTHVVARSKAGQVIGYAQVDRGGEDASAELVVHPEHRRAGVGGLLLRTAERDATLPQFGGTAGHHGKRLRVWAHGNLEPARAFAAAAGYVVVRELLFLTKPFPPVVAPVEPTPPVTEPVEPAPPVVEPVEPAPPVVEPVETTSASTSGVVSTGSTTGGGSTTGGGYRVRAFVPGVDDDAWVALNARAFAAHPEQGRLTVADLHDRMAEPWFDPAGFFLAEAPDGTLAGSLWTKVEGDDGEIYAVGVDPAHQGRGLGATLTAVGLDHLATRARRATLYVDGDNAAALATYARAGFVPTAVDVQYGKATGGTPVPRALPSR
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: YL66B_YEAST
Sequence: MSLRPCLTPSSMQYSDIYIHHTHTPHPHHTHTHTHHTPTHSLTSTFTLAVTPYPAF
What are the official names of this protein?
Uncharacterized protein YLL066W-B.
Protein: CLCA_CROS8
Sequence: MKSQTIPTRRVRGFRRAAVIRQLLSRDKTPLTILLLASLTGVLAGLAGVAFEKAVAWVTAHRIEGLAQVAHIPWLVWLLAFLFSALLAMVGYFLVRRFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFFGGMGTLGAGMVLGREGPMVQMGGNIGRMVLDIFHRPDAEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRTQFHYNLISIKAVFTGVIMSTIVFRIFNGEKSVIEVGQLTDAPVYTLWLYLLLGIIFGAVGPLFNRLVLGMQDVFARIHGGNTTRWVLLGGAIGGACGLLALWEPAAAGGGFGLIPIAAAGNFTVGMLLFIFIARVVTTVFCFSSGAPGGIFAPMLALGTLLGSAFGMACAAWFPQWHLQAGTFAIAGMGALLAASVRAPITGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQEAERQAQADGRNT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_CAMC5
Sequence: MIQSFTRLAVADNSGAKELMCIKVLGGSKRRYATLGDVIICSVKKALPNGKIKKGQVVKAVVVRTKKEVQRGNGSLIRFDENAAVILDNKREPIGTRIFGPVGREVRYANFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DDLA_BRADU
Sequence: MADKIRVVVLYGGRSGEHEVSLKSAASVFRHLDRTRFEVIPVSIDKTGRWQWNDLRSLDQAHAAALPILPDAPEMRLARGPDGRGVLVPITQGAAAPIAIDVVFPVIHGPLCEDGTVQGLLELADVAYVGSGVLASAVSMDKDVAKRLAEFAGIPVAPYRVLTRKAFVQDRVSSLAKAVEGLSLPVFVKPCNMGSSVGIHKVKTQDALEAALDDAFRYDVKVLVQQGIDAREIEVAVLEDETLFASLASELNPNAHHEFYSYEAKYLDPDGARVDLPARLDAAQMERVRSLATRVFAALECSGFARVDFFLDRKTGEFCFNEINTLPGFTSISMYPKMMEASGVPYGELLSRLVDLALDRHRQRQSLERGYAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_MYCTU
Sequence: MDDDAQMVAIDKDQLARMRGEYGPEKDGCGDLDFDWLDDGWLTLLRRWLNDAQRAGVSEPNAMVLATVADGKPVTRSVLCKILDESGVAFFTSYTSAKGEQLAVTPYASATFPWYQLGRQAHVQGPVSKVSTEEIFTYWSMRPRGAQLGAWASQQSRPVGSRAQLDNQLAEVTRRFADQDQIPVPPGWGGYRIAPEIVEFWQGRENRMHNRIRVANGRLERLQP
What is the function of this protein?
Catalyzes the oxidation of pyridoxine 5'-phosphate (PNP) into pyridoxal 5'-phosphate (PLP).  Unlike many PNPOx enzymes, Rv2607 does not recognize pyridoxamine 5'-phosphate (PMP) as a substrate.
What are the official names of this protein?
Pyridoxine 5'-phosphate oxidase, PNP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ALR_RICCN
Sequence: MSLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVASSEEGVNLRNALGLDVNILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ARG33_HUMAN
Sequence: MEKTKTKQGENEHMPVNNPSTQIYQLQALASELKTGFTEAMQELSRIQHGEYALEEKVKSCRCSMEEKVTEMKNSLNYFKEELSNAMSMIQAITSKQEEMQQKIEQLQQEKRRESRKVKAKKTQKEEHSSQAGPAQAQGSPFRSINIPEPVLPSEDFTNLLPSQAYEKAQESRSVHVGDSNVKGMMGPGVNPTTPEAEENLKSCLSADIQSKGHLPSGMWRQPKDGKEWGEEYVTKDHPDKLKEAGQGRHSSLENVLCETSLAAKRQTVALELLESERKYVINISLILKIKATFQGSDGKRNSKERSLFPGSLRYLVQQHLDLLHALQERVLKWPRQGVLGDLFLKLTNDENNFLDYYVAYLRDLPECISLVHVVVLKEGDEEIKSDIYTLFFHIVQRIPEYLIHLQNVLKFTEQEHPDYYLLLVCVQRLRVFISHYTLLFQCNEDLLIQKRKKLKKSSMAKLYKGLASQCANAGQDASPTAGPEAVRDTGIHSEELLQPYPSAPSSGPAITHLMPPVKKSQQQQSLMESMQPGKPSDWELEGRKHERPESLLAPTQFCAAEQDVKALAGPLQAIPEMDFESSPAEPLGNVERSLRAPAELLPDARGFVPAAYEEFEYGGEIFALPAPYDEEPFQAPALFENCSPASSESSLDICFLRPVSFAMEAERPEHPLQPLPKSATSPAGSSSAYKLEAAAQAHGKAKPLSRSLKEFPRAPPADGVAPRLYSTRSSSGGRAPIKAERAAQAHGPAAAAVAARGASRTFFPQQRSQSEKQTYLEVRREMHLEDTTRFCPKEERESEQTSFSDQNPRQDQKGGFRSSFRKLFKKKNGNATGEDFCGPWGWW
What is the function of this protein?
May act as a guanine-nucleotide releasing factor.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 33.
Protein: YFBU_ECOSE
Sequence: MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: LLDD_SALAR
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTLKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPAALAPMSKGDAT
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1320_LEGPA
Sequence: MLTLLSPAKKLLSISKHYSKETSNPLLLDKALQLVKIMKLKSVEQIADLMDLSRQLAELNYERYQNFDLKNNPMNHSYPALFLFQGDVYQGLNANSWKDEEIEYAQSHLGILSGLYGFLRPLDRIQPYRLEMGVNLENPAGKNLYAFWSKIVTNILNQILAEQSNPVLINLASTEYFKVVDEKKLSYPLVTINFYEQKNSELKMIGILAKKARGMMAKYIMQNRIDSIEQIKEFSESGYLFNKEISSPNSLNFI
What are the official names of this protein?
UPF0246 protein lpp1320.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: KTI1_XANSA
Sequence: PVVDTTGNNPLQQQEEYYV
What is the function of this protein?
Serine protease inhibitor.  Displays antimicrobial activity against the Gram-negative bacterium S. typhimurium ATCC 14028.  Displays no hemolytic activity.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 1, Xb-KTI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1815_ARCFU
Sequence: MGFTGRRGKAEIIEAFSKHVSPYKAKFFSMVGIDFVPARREGVWYWDLDGRKLMDCHCNGGVFNLGHRHPEIVKTLVEALDELDIGNHHLISEQRARLAEKLAELMPGDISRTVFGVGGGEAIDFAIKLARGHTGRKKIIYAKGGYHGHTGFALAAGDEKYRKPFEPLAPGFVEVPFGDAEAVEKAVDDDTAAVLFETIPATLGMPLPPEDFYRRVREICDEKGCLMIMDEVQTGLGRTGKMWGIEHYKVVPDVIVTAKGLSGGVYPISATCFKEGLDDFMAENPFIHVSTFGGAELGCVVAEKVLEITSRESFLENVRKTGEALSEILGKLKDEYDFVDEIRQKGLFIGIKMVEEGWGPLLSISCYHSGILAVYANNDTSVMQFLPPLIVGEKEVDYIREKLAGAMEIASQRREMVEFIRKML
What are the official names of this protein?
Uncharacterized aminotransferase AF_1815.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: NACAD_HUMAN
Sequence: MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM
What is the function of this protein?
May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER).  May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER.  May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
What are the official names of this protein?
NAC-alpha domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GYRB_MYCGE
Sequence: MEENNKANIYDSSSIKVLEGLEAVRKRPGMYIGSTGEEGLHHMIWEIVDNSIDEAMGGFASFVKLTLEDNFVTRVEDDGRGIPVDIHPKTNRSTVETVFTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSSSFKVWVFRQNKKYFLSFSDGGKVIGDLVQEGNSEKEHGTIVEFVPDFSVMEKSDYKQTVIVSRLQQLAFLNKGIRIDFVDNRKQNPQSFSWKYDGGLVEYIHHLNNEKEPLFNEVIADEKTETVKAVNRDENYTVKVEVAFQYNKTYNQSIFSFCNNINTTEGGTHVEGFRNALVKIINRFAVENKFLKDSDEKINRDDVCEGLTAIISIKHPNPQYEGQTKKKLGNTEVRPLVNSVVSEIFERFMLENPQEANAIIRKTLLAQEARRRSQEARELTRRKSPFDSGSLPGKLADCTTRDPSISELYIVEGDSAGGTAKTGRDRYFQAILPLRGKILNVEKSNFEQIFNNAEISALVMAIGCGIKPDFELEKLRYSKIVIMTDADVDGAHIRTLLLTFFFRFMYPLVEQGNIFIAQPPLYKVSYSHKDLYMHTDVQLEQWKSQNPNVKFGLQRYKGLGEMDALQLWETTMDPKVRTLLKVTVEDASIADKAFSLLMGDEVPPRREFIEKNARSVKNIDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_ACIC5
Sequence: MELKGKKVLVVGLGKSGLAAALFLRRRGAQVTVSDIRSAEALSKDIPALIEQGIAVEAGGHGLLTFRRQDLIVVSPGVPLDTPELVQVRKFGLPIIGEVELAARFLKGKTLAITGSNGKTTTTSLCGAILERAHQHVQVGGNIGLPVIALVDDSRDDGWSVLEISSFQLETTERFRPGIAVILNITPDHLDRHGSFENYVAAKERIFAAQTHDDALILNADDDAASRAAARASSRIFWFSRNRVIRQGAFVHEGNILFRAAEDAATEPILPLSEIPLKGAHNVENVLAAVCAARLAGVSAEAIRDAVRDFRAVEHRLEFVAEIGGVSFYNDSKATNVDAARKAIEAFPGGIHLILGGKDKNSDYRTLRPLMAGRVKAVYTIGSAAEKIMTHLDGAVPLIAAGTLDLAVNLAGGAASPGDVVLLAPACSSFDQFENYEQRGQVFKDLVLAHRGAAAWQNASA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPG1_BOVIN
Sequence: MHLEAARVIFFLWIFLQVQGIKDLSIKIYGSEIKDIDNAPRTEATKNTAKTYKVSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMEQILASLQAYYRLRVCQEAVWEAYRIFLDRLPEPGEYQDWVSVCQQETFCLFDIGKNFSNSQEHLDLLQQRMKQRNFLERKDEVVTKETLGELGQTPGLQQTLPVSHPGPCLSLPMTTAQRNPQLHPSRTPRVPTRERKIEFTDAAEDALEQKVELSISLANQKFKSELDNSQSPYYLEVAAKSQLQMQKIFKKLPGFKEIHVSGFRPKKERDGTSSTEMQLTAIFKKGKAEAKSPASDPLSLDSNKIESEGDPRGTTEEEKQRELYPTASELRKLISRALEEDQSLDVGTIQFTDEIVGSLPSLDPDTQLVLPTLLTDITKDATLSPELPLGQPRLETVDRAGHSPPGASPTDGWSPPAMTSTSLSETLPFFTASSVFPQTDQSATDIMSIDQTVLIPRLTVPTDDYSAISPLVPEISHLPTSSEDWLSTSSQDTMEYLDGVDLTKTPTSSEGPRNSVGMFPAWIIFLENITPDPGLRYITTSAMTVAARGRELVVFFSLRVANVPFSTDLFNKSSLEYQALEQRFTQLLVPNLRSNLTGFKQLEILNFRNGSVIVNSKVRFAKSVPYNLTKAVRGVLEDFRSTAAQQLDLEIDSYSLDVEPADQADPCKFLACGEFAQCVRNEWTEEAECRCRSGTQALVLPIEDCEDIPGKGTPCRSLDQSKNQVYEPGVKKFQRQQDNKVTMKRKFELLTIGYEEFNYQDWEGN
What is the function of this protein?
Chondroitin sulfate-, heparin- and hyaluronan-binding protein (By similarity).  May serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix (By similarity).
What are the official names of this protein?
Interphotoreceptor matrix proteoglycan 1, Mucin-like glycoprotein associated with photoreceptor cells, Sialoprotein associated with cones and rods.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Photoreceptor inner segment.
Protein: ISPD_PROA2
Sequence: MSSVAIIAASGVGKRMNLRNGLSKQFLEIGGYPVIYHTLAAFQRASSIDKIYIATKPDSIATLETLAEEHQFSKINAIIAGGKERQDSISNCIELIALHIEKAEIDRPDTILVHDGARPFITPDEIDQIAQLSHHYGACVPATKPKDTIKYISDQPGFFGETLDRSLLLQVQTPQGFASEKLVEAHRKAREAESYATDDAALVEKFFPDQKIKVFEMGYHNIKITTPEDIFLGEAIYAQLQQQS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TRHO_BURO0
Sequence: MTIVNLAAYHFVSLDANEQWRPLVTARCNELGLRGTILLAPEGINLFIAGTREATDAFIAYIRHDPLFEGKFATLQFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPFVDARTLKAWLDRGHDDAGRPVVMLDTRNAFEVDVGTFDNALDYRIDKFSEFPEVIDANRADLEGKTVVSFCTGGIRCEKAAIHMKEIGIDNVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLQPTENVTCFACRAVVTPEAQQSPSYVPGKSCPACAQAASAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: TRM82_YEAS1
Sequence: MSVIHPLQNLLTSRDGSLVFAIIKNCILSFKYQSPNHWEFAGKWSDDFDKIQESRNTTAKEQQGQSSENENENKKLKSNKGDSIKRTAAKVPSPGLGAPPIYSYIRNLRLTSDESRLIACADSDKSLLVFDVDKTSKNVLKLRKRFCFSKRPNAISIAEDDTTVIIADKFGDVYSIDINSIPEEKFTQEPILGHVSMLTDVHLIKDSDGHQFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWDWKTGKNLSTFDYSSLIKPYLNDQHLAPPRFQNENNDIIEFAVSKIIKSKNLPFVAFFVEATKCIIILEMSEKQKGDLALKQIITFPYNVISLSAHNDEFQVTLDNKESSGVQKNFAKFIEYNLNENSFVVNNEKSNEFDSAIIQSVQGDSNLVTKKEEIYPLYNVSSLRKHGEHYS
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUC_MOOTA
Sequence: MGMTITEKILAAHAGLKAVEPGQLINAKVDLALGNDITAPLAIQEFKKLGVKKVFDPERVVLVPDHFTPAKDIKSAEQAKILRDFAREQGLTHYFEIGRMGIEHCLLPEAGLVGPGDLVIGADSHTCTYGALGAFATGVGSTDLAAAMATGELWFKVPETILFRYHGKLKPWVGGKDLILYTIGRIGVDGARYMAMEFTGEAITNLSMEGRFTMANMAIEAGGKNGIFPVDEKTVEYIRGRLQRDYRIYQSDPDARYNQEIDIDASKIEPQVALPHLPENARSVKEIGEIKIDQVVIGSCTNGRLEDLRVAAQILKGQKVHPEVRLIVIPGTQQIYAAALAEGLIATFIEAGAAVSTPTCGPCLGGHMGILAKGERALATTNRNFVGRMGHPESEVYLAGPAVAAASAVKGRIAAPEEVVK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: MLC1_DROYA
Sequence: KKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGENLDDEQVETLFADCMDPEDDEGFIPYSQFVQRLMSDPVVFD
What are the official names of this protein?
Myosin light chain alkali.