PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_LISW6
Sequence: MKVAVSGFKGRMGHEVVKTVLREEDLELVAVLDHEPKEKNIREIVEFSSLDVPVYANLSEMLEEAKPDCVVDFTTPKVGYSNTKTILEHGVRAVVGTTGFTPEQIESLREIAETKKIGALIAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAPSGTAVKTAEMMAENRTFVKQGAEDEVELMEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSGVALSIRKTKELETLIYGLENILD
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_LACH4
Sequence: MKFEDFKIMATASSAPDHVVTNDELATMMDTSDEWITQRTGIKRRRIATEETTSSMCTDVATQLIAQSDLTAKDIDLIAVATMSPDYLTPSVSAMVQGNIGADHAIAFDIDAACSGFVYGLHLVKQMLIANQQKNAILIGGETLSKLLDWSDRSTAVLFGDGAGGVLIRNTAVDKGSFISEDLRTLGNLGQYLTAGQTGNPSPFATDQQPFSPFFKMSGRRVYSFAVKNVPESINDALKQANLTADEVDCFVLHQANRRIVERIADELAVSMAKFPINIDEYGNTAAASEPILLDQLVKQKIIKRGDVIALSGFGGGLTVGTMIMKY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CHLCV
Sequence: MFGEGSRDNATLSKEGLFDKLEIGIASDITIRDKWSCGEIKKPETINYRTFKPEKGGLFCEKIFGPTKDWECCCGKYKKIKHKGIVCDRCGVEVTLSKVRRERMAHIELAVPIVHIWFFKTTPSRIGNVLGMTASDLERIIYYEEYVVIDPGKTDLNKKQLLNDAQYREVVEKWGKDAFVAKMGGEAIYDLLKSEDLQSLLKELKDRLRKTKSQQARMKLAKRLKIIEGFVSSSNHPEWMVLKSVPVVPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKAILRLKTPEVIVRNEKRMLQEAVDALFDNGRHGHPVMGAGNRPLKSLSEMLKGKNGRFRQNLLGKRVDYSGRSVIIVGPELKFNQCGLPKEMALELFEPFIIKRLKDQGSVYTIRSAKKMIQRGAPEVWDVLEEIIKGHPVLLNRAPTLHRLGIQAFEPVLIEGKAIRVHPLVCAAFNADFDGDQMAVHVPLSIEAQLEAKVLMMAPDNIFLPSSGKPVATPSKDMTLGIYYLMADPTYFPEDHGGKIKIFRDVTEVLRALYTGGFLDERINNRCDETGRGIHIHEKIKVRIDGQIIETTPGRVLFNRIVPKELGFQNYSMPSKRISELILQCYKKVGLEATVRFLDDLKDLGFIQATKAAISMGLKDVRIPEIKSEILKEAYDKVAVVKKQYDDGIITDGERHSKTISIWTEVSELLSDALYVEISKQAKSKHNPLFLMIDSGARGNKSQLKQLGALRGLMAKPNGAIIESPITSNFREGLTVLEYSISSHGARKGLADTALKTADSGYLTRRLVDVAQDVIITEKDCGTLNHIEISAIRQGSEELLPLKDRIYGRTVSEDIYQPGDKSKLLAKNGDVVTSAQAELIDDAGIESIKIRSTLTCESRRGVCAKCYGLNLANGRLIGLGEAVGIIAAQSIGEPGTQLTMRTFHLGGIAATSSTPEIVTDNDGILVYMDLRVVVGQDGNHLVLNKKGAIHVVRDEGRSLEEYKKLLSTKSIESLETYPVELGVKILVGDGEKVSSGQRIAEVELHNIPIICDKPGFVKYEDLVEGISTEKVVNKNTGLVELIVKQHRGELHPQIAIYSDAGLTELVGTYAIPSGAIISVEENQKVDPGMLLARLPRGAIKTKDITGGLPRVAELVEARKPEDAADIAKIDGVVDFKGIQKNKRILVVRDEITGMEEEHLIPLTKHLIVQRGDNVMKGQQLTDGLVVPHEILEICGVRELQKYLVNEVQEVYRLQGVDINDKHIEIIVRQMLQKVRITDPGDTTLLFGEEVNKKEFYEENRRTEEDGGKPAQAVPVLLGITKASLGTESFISAASFQDTTRVLTDAACSSKTDYLLGFKENVIMGHMIPGGTGFDTHKRIKQYLEKEQEDLVFDFESESECAC
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RUVA_GEOSL
Sequence: MIALLTGRLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPEEGKTVSLSIHTHVKEDSISLFGFRTLAEKEFFQLLISVSGIGPKMARDILSNIQPEELAAAIVQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSAQEAPSSEAPAEVADDVASALVNLGYKEAVVRKVLAEMSIEPDASTEAVLRQALKVLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DXR_PHOPR
Sequence: MRKLTILGATGSIGSSTLAVAAQNPQLFEVVALAAGTNSQKMLELCRIWKPKYAAMASLQAAKELSVLLEKHEISTQVLAGDAGLCQVAALDEIDTVMAAIVGAAGLLPTMAGVKAGKRILLANKEALVMSGQMFIDACEQYGAELLPVDSEHNAIFQCLPADIQRAMGRCDLEEYGISKILLTGSGGPFRYTDIAELASVTPQMAIAHPNWSMGPKISVDSATMMNKGLEYIEARWLFNASREQLQVIIHPQSVIHSMVQYKDGSVLAQMGLPDMQTPIACAMSYPDRVDAGVAPLDFSKIGEFTFLPPDYSRYPCLKLAIDACYDGQAATTALNAANEIAVAAFLNNDIGFTDIAIINEQILNSANMATLVDLESVIELDMQARVLAHNIIRKVA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GSHAB_PASMU
Sequence: MKIQHIIHENQLGLLFQQGSFGLEKESQRVTADGAIVTTPHPAVFGNRRYHPYIQTDFAESQLELITPPTKKLEDTFRWLSVIHEVVQRSLPEEEYIFPLSMPAGLPAEEQIRVAQLDNPEDVAYREYLVKIYGKNKQMVSGIHYNFQLSPDLITRLFRLQNEYQSAVDFQNDLYLKMAKNFLRYQWILLYLLAATPTVESAYFKDGSPLAKGQFVRSLRSSQYGYVNDPEINVSFDSVEKYVESLEHWVSTGKLIAEKEFYSNVRLRGAKKAREFLTTGIQYLEFRLFDLNPFEIYGISLKDAKFIHVFALFMIWMDHTADQEEVELGKARLAEVAFEHPLEKTAYAVEGELVLLELLSMLEQIGAEPELFEIVKEKLTQFTDPSKTVAGRLVRAIEQAGSDQQLGAQLAQQYKAQAFERFYALSAFDNMELSTQALLFDVIQKGIHTEILDENDQFLCLKYGDHIEYVKNGNMTSHDSYISPLIMENKVVTKKVLQKAGFNVPQSVEFTSLEKAVASYALFENRAVVIKPKSTNYGLGITIFQQGVQNREDFAKALEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVVGDSVHSVAELVAMKNDHPLRGDGSRTPLKKIALGEIEQLQLKEQGLTIDSIPAKDQLVQLRANSNISTGGDSIDMTDEMHESYKQLAVGITKAMGAAVCGVDLIIPDLKQPATPNLTSWGVIEANFNPMMMMHIFPYAGKSRRLTQNVIKMLFPELE
What is the function of this protein?
Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
What are the official names of this protein?
Glutathione biosynthesis bifunctional protein GshAB, Gamma-GCS-GS, GCS-GS.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
Protein: TGT_BACC2
Sequence: MTAIRYEFIKTCKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEELKAMDSGIILSNTYHLWLRPGHEIIREAGGLHKFMNWDRAILTDSGGFQVFSLSDFRRIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLKAHERPQDQGLFGIVQGGEYEELRRQSAKDLVSMDFPGYAVGGLSVGEPKDIMNRVLEFTTPLLPDNKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFARDFGPLDPNCDCYTCKNYSRAYIRHLMKCDETFGIRLTSYHNLHFLLNLMEQVRQAIREDRLGDFREEFFEQYGFNKPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: Y3813_PSEP1
Sequence: MDTKLLDILACPITKGPLKLSADKTELISKGAGLAYPIRDGIPVMLESEARTLTDDERLDK
What are the official names of this protein?
UPF0434 protein Pput_3813.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: AHP3_ARATH
Sequence: MDTLIAQLQRRFCDFTISLYHQGFLDDQFTELKKLQDECSPDFVAEVVTLFFEDCEKLISNMARALDQTGNVDFKLVGSSVHQLKGSSSSVGAKRVKGLCVTLKECCDSQNYEGCVRCLQQVDIEYKTLKAKLQDLFNLEQQIVQAGGRIPQVDI
What is the function of this protein?
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs).  Plays an important role in propagating cytokinin signal transduction through the multistep His-to-Asp phosphorelay.
What are the official names of this protein?
Histidine-containing phosphotransfer protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: Y513_METJA
Sequence: MMIMVKYGIKIEDDRVEIVRYSTVYTDEGVEELEEIYLQIKADDYESILGIYEPYPKKDVRFVGNLDDLKVVKGQEMRTAVPIPLSLCRAKYLKRIDEDDERITYLDINGVPIQRGIIVGIVVGVQHKRTSTGKDYTIFRIFDGYGWGRLRLFGIKANPEIFTGMFIRGFVRFGAVEFRTEEGELRKAISLTLNDIPVIVQPKEYIVHKKFIDEVVLPRVAPELIEEDKEEEETDEETINS
What are the official names of this protein?
Uncharacterized protein MJ0513.
Protein: YBJQ_ECO81
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RSXE_ECO81
Sequence: MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAAAERALPNGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNFA_PROMH
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGFATTFVMTIASISSWLMDTFILVPLDLLYLRTLSFILVIAVVVQFTEMVVRKTSPTLYRLLGIFLPLITTNCAVLGVALLNINQSHTFMQSAVYGFGAAVGFSLVMVLFAAIRERLAVANIPAPFKGSSIGLITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 14331_ECHGR
Sequence: MSRLAECTISDTVDELVQRAKLAEQAERYDDMAGACKTMAKMRNELNNEEANLLSVAYKNVVGARRSSWRIMSSIAKKQAGTPLAHQHDIYLKKVEEELIQICNDVLALPVLPITEKIGAEAKIFYYKMMGDYYRYSAEVQEGEQNDKSTEAAEEANQKATSLAEAELSVTHPIRLGLALNFSVFYYEIKNMPEKACSLAKAAFDAAITEVDSIKDETYKDSTLIMQLLRDNLTLWNSECETDS
What are the official names of this protein?
14-3-3 protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: FOXL1_HUMAN
Sequence: MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ
What is the function of this protein?
Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium.  Target gene of the hedgehog (Hh) signaling pathway via GLI2 and GLI3 transcription factors (By similarity).
What are the official names of this protein?
Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBAN_ECO57
Sequence: MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSPRFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLLVILACLLFYMWRIPVIDEKQEKH
What are the official names of this protein?
Inner membrane protein YbaN.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGS1_HUMAN
Sequence: MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK
What is the function of this protein?
May be involved in collagen fiber assembly.
What are the official names of this protein?
Biglycan, Bone/cartilage proteoglycan I, PG-S1.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: US03_HCMVT
Sequence: MKPVLVLAILAVLFLRLADSVPRPLDVVVSEIRSAHFRVEENQCWFHMGMLHYKGRMSGNFTEKHFVSVGIVSQSYMDRLQVSGEQYHHDERGAYFEWNIGGHPVPHTVDMVDITLSTRWGDPKKYAACVPQVRMDYSSQTINWYLQRSIRDDNWGLLFRTLLVYLFSLVVLVLLTVGVSARLRFI
What is the function of this protein?
Retains, but does not degrade MHC class I heterodimers in the endoplasmic reticulum during the immediate-early period of virus infection, thereby impairing their transport and maturation.  Forms a complex with beta-2-microglobulin-associated class I heavy chains, which accumulate in the ER.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
What are the official names of this protein?
Membrane glycoprotein US3.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US2 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: SECA_ECO81
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GCST_THET8
Sequence: MKKTPLYEAHLRLGARMVDFAGYLLPLQYTSIVEEHLAVRRAVGVFDVSHMGEFLVRGKEALAFLQWATANDAGKLKVGRAQYSMLPNERGGVVDDIYLYRLGEEEYLMVVNAANIAKDLAHLQALAKGFRVELEDASERTALLALQGPKAASLLQGLTDLDLSQKRKNDVFPARVAGRPARLARTGYTGEDGFELFLAPEDAEPVFLALVEAGAKPAGLGARDSLRLEAGFPLYGHELTEETNPLCTPWAWVVKKEKAFLGKEAMLAQACRERLVGLVLEGGIPREGYRVLSGGRPVGRVTSGGYSPLLQRGIALAYVEEGAEGPFQVEVRGRAVPAALSPLPFVPLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: AROQ_ENT38
Sequence: MADKFHILVLNGPNLNMLGTREPEKYGSLTLSEIVNRLSTEATSLNVELDHFQSNAEYAIIDRIHQAKDTVDYILINPAAFTHTSVAIRDALLAVSIPFIEIHLSNVHAREPFRHHSYLSDIAAGVICGLGADGYSYALQTAVKRLSQSH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL18E_PYRFU
Sequence: MKRTGPTDPNLRRLIRYLRKKSNEYGVKIWKDVAWRLERPRRQRAEVNVSKINRYANDGEMIVVPGSVLGAGKLEKKVIVAAWKFSETARRKIIEAGGEAITIEELIERNPTGSGVRIME
What are the official names of this protein?
50S ribosomal protein L18e, Large ribosomal subunit protein eL18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: TFE_METKA
Sequence: MYAELGEEDLEVLRDVTLSLLDSEKGVDPEVAKRTVDVILKREAIDEEIAEELGVDPREVRKVLYKLHERGVVTFRKERREEYRYPVYSWRLNLREVLRRCLEERRRELEEVERALSNDMSHPMFHCGNDDCPRMSFEEAMEHEFRCPKCGEVLEEVDLTEERRELERLAEELKVEIRRLEELRERLG
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: PAND_SALNS
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWRPKVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_BRUSU
Sequence: MQHAAVCSGTSRHRRTTVTIEKPPATSAPIVEMKDVRRMFGETAAINGVSLSVARGEILGIIGRSGAGKSTLIRCVNGLEKPDTGSIHIEGREITSLDEDALRPVRRRIGMVFQHFNLLSAKTAAQNIALPLKIAGMPKAERIKRVAELLELVGLSDKASHYPAQLSGGQKQRVGIARALAAEPAVLLSDEATSALDPETTQSILALLKDINAKLGLTILLITHEMDVIRRIADRVIVLDHGLIAEEGPVWKVFANPQSPVTQSMLQVLTPELPAIWRNRLEKKGDQAILRVKLSGMAAKGAFFNDVAAATSLAPQLIHGGMDTIQGEPVGTLFIGLPAEDKTKLKAAIGYLNTHADATEVLGYVSGNA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NEP_I68A4
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: COXX_SULTO
Sequence: MKITRIYVRLMAISLSRKLIDYIKLSKPRVISLLDLAAIAGFVLGLPKAINITSIIVSFLAVIIGGSLASGGGMIINGGLEIEKDKKMKRTSWRPTVKGEVGRKEAYAIGSIFIVVGTLIGFLANPLTALFIALGAFIYVVIYSIWLKPRTWWNIVIGGFAGSAAAWAGFAASSGSFTLLSFLLGFLIFMWTPGHFWSLALRFRDDYKNAEIPMLPVLTDERTSAKAIAISNALMVPFALLIGLYAGLIYLIVSTIVSAFLLYVSVKLYLNPTADEAWESFKLSSPYLAIILLTLIIVKLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAZ_STAAN
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.