PharMolix/UniProtQA huggingface dataset:
Protein: FPG_SHEPA
Sequence: MPELPEVEVTRQGVSPYLIDNTVTDLIVRNPSLRWPVPEIAKQIIGQTIRNVRRRAKYLLIDTDAGTTIVHLGMSGSLRILPATTPAEKHDHIDLVLASGKALRFNDPRRFGAWLWCELPEQAHPLLSKLGPEPLTDAFNAPYLLESLANKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPQAEAGKVDAERIEILVSEVKQILAGAIKQGGTTLKDFTNADGKPGYFAQKLHVYGRGGKTCTQCGHMLSEIKLGQRATVFCSLCQQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: INLI_LISMO
Sequence: MKKKFSIVIISVLLLGYLAPFDTLLVGADETTVSEDTAVKTAEADSATEGIESETGSDDETAEEPKEAKEAEASKETTEKEEKAKTEEPASNIKTEINTDKSQLKQTSLKAAVPAGSTYNSLFPDDNLAKKLAVIITGNAAATGNESVDSAALLAISQLDLSGETGNDPTDISNIEGLQYLENLTSLNLSENNISDLAPLKDLVNLVSLNLSSNRTLVNLSGVEDLVNLQELNVSANKALEDISQVASLPVLKEISAQGCNIKTLELKNPAGAVLPELETFYLQENDLTNLTSLAKLPKLKNLYIKGNASLKSLETLNGATKLQLIDASNCTDLETLGDISGLSELEMIQLSGCSKLKEITSLKNLPNLVNITADSCAIEDLGTLNNLPKLQTLVLSDNENLTNITAITDLPQLKTLTLDGCGITSIGTLDNLPKLEKLDLKENQITSISEITDLPRLSYLDVSVNNLTTIGDLKKLPLLEWLNVSSNRLSDVSTLTNFPSLNYINISNNVIRTVGKMTELPSLKEFYAQNNSISDISMIHDMPNLRKVDASNNLITNIGTFDNLPKLQSLDVHSNRITSTSVIHDLPSLETFNAQTNLITNIGTMDNLPDLTYVNLSFNRIPSLAPIGDLPNLETLIVSDNNSYLRSLGTMDGVPKLRILDLQNNYLNYTGTEGNLSSLSDLTNLTELNLRNNVYIDDISGLSTLSRLIYLNLDSNKIEDISALSNLTNLQELTLENNKIENISALSDLENLNKLVVSKNKIIDISPVANMVNRGAIVTASNQTYTLPTVLSYQSSFTIDNPVIWYDGTLLAPSSIGNSGNYKDGKITWTNMTATSSSTLFNFNRLKDGLTFSGTVTQPYKSAAKVTADAEQTYTIGDTISEEQFLKDVNAKSSDGAPVTSDFATVVDLNTFGEYEVTLTSEKDGIQGDSCKVIVKVLHGAPVISADQTISYDKHATITEKQFLEDIHASTDLDTAITTNFSTAVNLNKGGDYTVALNSENEDGVKAETVYVTVTVNKDPAPIISAKTEITYDKFSKKTEAAFLDDIDADTNDGSIVTSNFATAVNLDKAGDYTVTLNSINSDGVAGTPTAIIVHVEKEKIATISTNTAQQYEKYAKINETQFLKDVHASINASPTTAVLESDFETVVKLDVPGTYTVTITATNEDGGVSAPKEVSVIVRKIPAPEITADKEITYPKFDEVSEAEFLNDIHATISDKNVAITSNFSTDVNLNKAGDYTVTLNATNEDGVKATPVEVIVHVQQGERPVITADATISYDKFANITEAKFLEDIHATSSDGQSSTVITSNFQTATNFKTAMSYTVTLNAVNEDGISAEPVAVTVTINKEPAAALKADAEVSYAKNEAVTESDFFKDVHLEGTEAPSTAKATSNFDSVVDRSKTGDYTVTINATNEDGAVSTPIEVIVHIEAESAPVITANAEVKYNKHEQTDERRFLYDSEAKIDEANVEIKTDFAEKVDINKVGTYTVTLTATNEDGQAANPVEVSVIVSDAAAEKVNVKYVDENGSEISAAETLTGNLDETFSIDAKSIAGYKCDATLSGVFSTVEQTVVFHYKAIKPGVVTIKYEDTNGKAVDEDKQITGEVGDDFEAEAQTVSGYSCRAIASGKITEEPQTITFTYSTATPSKKSGEITVQYVDESGKKLADSKKVTGNIDDSYSVEAKAIEGYSVVGDDSAKGVFTEKSQTVTFKYKKNTQVSKDDPKVKGKTNQPSSTDTKLKVDNNSLPATGDTENMILAVLIGFNMLIVASIFLFRKPKTNQ
What is the function of this protein?
A role in virulence could not be demonstrated.
What are the official names of this protein?
Internalin I.
What is the protein family that this protein belongs to?
Belongs to the internalin family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: AZOR_STAA9
Sequence: MAKVLYITAHPFNELVSNSMAAGKAFIETYQQQHPDDEVKHIDLFETYIPVIDKDVLTGWGKMSNGETLTDDEQMKVSRLSDILEEFLSADKYVFVTPMWNLSFPPVVKAYIDAISIAGKTFKYSAEGPQGLLTDKKVLHIQSRGGYYTEGPAADFEMGDRYLRTIMTFLGVPSYETIIIEGHNAEPHKTEEIKATSINNAEKLATTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CUTA_YERPP
Sequence: MSDSDAMTDPNAVSYSNAIVVLCTAPDEASAQNLAAQVLGEKLAACVTLLPGATSLYYWEGKLEQEYEVQLLFKSNTDHQQALLTYIKQHHPYQTPELLVLPVRDGDKDYLSWLNASLL
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_HISS2
Sequence: MSNSITKNLSKHKLVKDTLVLILAGGRGSRLHELTDKRAKPALYFGGNRRIIDFALSNCINSGLNRIGVVTQYAAHSLLRHLQKGWSFLPQERGEFIDMLPARQQIDDSTWYRGTADAVYQNMAIIRDHYRPKYILILAGDHIYKQDYSQMLLDHVSSNAKCTVGCIEVPREQASEFGVMAVDENLKVKAFVEKPKDPPAIPNKPDTSLASMGIYVFDADYLYDVLMREVNTPYTSHDFGKDILPKSLEEEVLYAHPFSRSCMGRNTDGEIYWRDVGTLDSFWQSNIDLVSEHPQLDIYDQRWPIRGNPTQTYPSKFFYNKQDIKPVDNSLISGGCVITDAEISYSVLFDQVKVKADSKVEYSVVLPQVTIGKNCILRNCIIDRQVVIPDNTVIGVNIEEDRKRFRVSSTGKVILVTESMMKKLNGEKVVSEIHLD
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: Y5172_BACAN
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BA_5172/GBAA_5172/BAS4807.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: BNIP3_MOUSE
Sequence: MSQSGEENLQGSWVELHFSNGNGSSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRAEIDSHSFGEKNSTLSEEDYIERRREVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSADFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF
What is the function of this protein?
Apoptosis-inducing protein that can overcome BCL2 suppression.  May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2 (By similarity).  Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria.  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity).  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity).  Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway (By similarity).
What are the official names of this protein?
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the NIP3 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Note=Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane (By similarity).
Protein: INP5K_HUMAN
Sequence: MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTSDFPSSPWDWIGLYKVGLRDVNDYVSYAWVGDSKVSCSDNLNQVYIDISNIPTTEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI
What is the function of this protein?
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (PubMed:10753883, PubMed:16824732).  Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (PubMed:10753883).  Negatively regulates assembly of the actin cytoskeleton.  Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (By similarity).
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase K, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase, Phosphatidylinositol-4,5-bisphosphate 5-phosphatase, Skeletal muscle and kidney-enriched inositol phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm. Note=Following stimulation with EGF, translocates to membrane ruffles (PubMed:12536145, PubMed:26940976). Concentrated at the periphery of the nucleus (PubMed:10753883).
Protein: GRA6_TOXGO
Sequence: MAHGGIHLRQKRNFCPVTVSTVAVVFVVFMGVLVNSLGGVAVAADSGGVKQTPSETGSSGGQQEAVGTTEDYVNSSAMGGGQGDSLAEDDTTSEAAEGDVDPFPVLANEGKSEARGPSLEERIEEQGTRRRYSSVQEPQAKVPSKRTQKRHRLIGAVVLAVSVAMLTAFFLRRTGRRSPQEPSGDGGGNDAGNNAGNGGNEGRGYGGRGEGGAEDDRRPLHPERVNVFDY
What is the function of this protein?
Major granular component involved in excreted-secreted antigen (ESA) immunity.  May have a structural role in the membranous network of the parasitophorous vacuole (PV).
What are the official names of this protein?
Dense granule protein 6, Protein GRA 6, Antigen p32, Protein p33.
What is the protein family that this protein belongs to?
Belongs to the Gra6 family.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole lumen. Parasitophorous vacuole membrane. Cytoplasmic vesicle, secretory vesicle. Note=Located in dense granules of tachyzoites. Upon infection, secreted into the parasitophorous vacuole (PV) and targeted to the microvillus membranous network.
Protein: NELL2_PONAB
Sequence: MESRVLLRTFCLIFGLGAVWGLGVDPSLQIDVLTELELGESTTGVRQVPGLHNGTKAFLFQDTPRSVKASTATAEQFFQKLRNKHEFTILVTLKQTHLNSGVILSIHHLDHRYLELESSGHRNEVRLHYRSGSHRPHTEVFPYILADDKWHKLSLAISASHLILHIDCNKIYERVVEKPSTDLPLGTTFWLGQRNNAHGYFKGIMQDVQLLVMPQGFIAQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERTCTMKGTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPLNSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDFCSERHNCMENSVCRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRCLQGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQCKNGHICCSVDPQCLQEL
What are the official names of this protein?
Protein kinase C-binding protein NELL2, NEL-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: SECB_CUPPJ
Sequence: MSDQQNTQQEDQPFFNIQRVYLKDMSLEQPNSPGIFLESEAPSVEVQVNVAASQLQEGIFEVVVTGTVTTKVQEKVAFLVEAHQAGIFDIRNVPVEQLDPLLGIACPTILYPYLRGNIADVITRAGFQAIHLSEINFQALYEQRLQAAMEEAQAAGGANSGIVMPDGSQARH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPP_KLEP7
Sequence: MHHVVSATTNPAKIQAILQAFDEIFGEGSCHIESVAVESGVPEQPFGSEETRAGARNRVANARLARPNADFWVAIEAGIDDDSTFSWVVIESASQRGEARSATLPLPDVILEQVRAGEALGPVMSQYTGIDQIGRKEGAIGVFTGGRLTRSSVYHQAVVLALSPFHNAIYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: SYQ_XANC8
Sequence: MSEIPATDATAPAEKKDFIRQIVREDLASGKHTAIRTRFPPEPNGYLHIGHAKAICLDFGLAAEFGGLCNLRLDDTNPAKEDPEFVVAIQDDVRWLGFEWAQLRHASDYFEVYYLAAEKLIRDGHAFVCDLSAEQVRQYRGTLTEPGRNSPFRERSVDENLDLFRRMRAGEFPDGARTLRAKIDMASGNINLRDPALYRIKHVEHQNTGNAWPIYPMYDFAHSLGDAVEGITHSLCTLEFEDHRPLYDWCVDKVDLSGHPELLAPLLGKGYPKEAAKPRQIEFSRLNINYTVMSKRKLTALVEEQLVDGWDDPRMYTLQGLRRRGYTPAAMRLFVDRVGISKQNSVIDFSVLEGCLREDLDAAAARRMAVIDPLKLVLTNLPEGHTETLQFSNHPKDESFGTREVPFARELWIEREDFAEVPPKGWKRLVPGGEIRLRGAGIARVDEVIKDAAGEIVELRGWLDPESRPGMIGSNRKVKGTIHWVSAVHAVEAEIRLYDRLFSVEKPDDESEGKTYRDYLNPESKRSVRGYVEPSAAQAAPEQAFQFERTGYFVADRRDHSAATPAFNRSVTLRDTWAK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPC_STRP6
Sequence: MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMRTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ
What are the official names of this protein?
Probable ATP-dependent Clp protease ATP-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: SPAK_BACIU
Sequence: MGIGFKGRKTLLRELVKYMVTLCISLVVLALLYIFINTIAMNTGFSHPANYNEREAEKLAPKLETIDKVTADMIPDTMSYAILNKETKQKTAGTIKEKDLQLVKKKIEKKPYVNYKQKGYLVIERNNEYCVLQYSLRADFSSPLLRKYLPNYELTSICILIILLIIVISIITTYFANRLRKHFETLNVITRYIKEQNLQFTPEFTHIKEFDDVIDSLIEMRDALQSSLEALWRLEKNKKEQIGALAHEIKIPITIIKGNAELLSLSMQNEEQAEYTKYILGAGNQIEQYIYQLIHLSKTEDALTIHLEKASVDELTETLVKDISAYKGNKNINISFKKENLMKEAKIDWQLLHRALLNILTNAVDYTPEGGTVSVHAECDSEIFYFFVKDTGNGFSEMGLKKATELFYMDDKSRHSKGHYGMGLTFAKNAVNLHNGELTLGNTIAGGAEVRVKIPLRNE
What is the function of this protein?
Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin.  SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals.
What are the official names of this protein?
Sensor histidine kinase SpaK, Subtilin biosynthesis sensor protein SpaK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2767_BORPE
Sequence: MESRLLDILVCPVCKGRLEFQRAQAELVCNADRLAFPVRDGVPIMLEAEARSLDAEAPAQPS
What are the official names of this protein?
UPF0434 protein BP2767.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NEPI_SALPA
Sequence: MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMVSFANSFTLLLLGRACLGLALGGFWAISASLTMRLVPARTVPKALSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVLKRSVKLALAGAPLLLALSALTLIVWGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGGLMLLTALVVAAKVRITPMS
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HBEAG_DHBV1
Sequence: MWNLRITPLSFGAACQGIFTSTLLLSCVTVPLVCTIVYDSCLYMDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTTPVPPGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEAQVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQVAQGGRKTTTGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPTPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYC4_THIRO
Sequence: TDGHQAAAPQVGDPQAGEAKANGVCLACHGPQGNSLVPIWPKLAGQHPEYIVKQLMDFKQRRANEQMTPMAMPLTDQEVLDLAAYYATQPKTPGAADPELASKGESLYRWGNPETGVPACSGCHGPAGGAGQSLAKFPRLSAQHADYTKQTLEHFRGALRANDPNGMMRGAAARLSDQEIAAVSQYLQGLSQ
What is the function of this protein?
Diheme, high potential cytochrome c believed to be an intermediate electron donor in an anaerobic electron transport chain.
What are the official names of this protein?
Cytochrome c4.
What are the subcellular locations of this protein?
Periplasm.
Protein: NA13_ANTEL
Sequence: GVPCLCDSDGPNVRGNTLSGTYWLAGCPSGWHNCKSSGPLIGACCKQ
What is the function of this protein?
Modifies current passing through the fast sodium channel (Nav) in neuroblastoma cells, leading to delayed and incomplete inactivation.  Paralyzes the shore crab (C. maenas) by tetanic contractions after intramuscular injection.
What are the official names of this protein?
Delta-actitoxin-Ael1c, Delta-AITX-Ael1c, Toxin APE 1-2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: MTND_PSEAB
Sequence: MSSLTVYHENQPEQPLKLLTHAEDIASTLAEVGVRFERWEAAAPIAAGASQDEVIAAYAHEIERLKRERGYITVDVVSLNSDHPQKAELRAKFLDEHRHGEDEVRFFVAGRGLFVLHIEEHVYAVLCERNDLISVPAGTRHWFDMGEHPHFVAVRLFNNPEGWVAQFTGDDIASRFPLLED
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: ALB1A_PEA
Sequence: MASVKLASLIVLFATLGMFLTKNVGAASCNGVCSPFEMPPCGTSACRCIPVGLVVGYCRNPSGVFLRTNDEHPNLCESDADCRKKGSGNFCGHYPNPDIEYGWCFASKSEAEDFFSKITPKDLLKSVSTA
What is the function of this protein?
PA1b binds to basic 7S globulin (BG) and stimulates its phosphorylation activity.  Involved in the signal transduction system to regulate the growth and differentiation as a hormone peptide.  Toxic to various insects through binding to a high affinity binding site in the insect gut (By similarity).
What are the official names of this protein?
Albumin-1 A, PA1 A.
Protein: CIRA_CHAPA
Sequence: GIPCGESCVWIPCISAALGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has antibiotic activity.  Inhibits the cytopathic effects and replication of the human immunodeficiency virus.  Active against the Gram-positive S. aureus with a minimum inhibition concentration of approximately 0. 2 microM.  Relatively ineffective against Gram-negative bacteria such as E. coli and P. aeruginosa.
What are the official names of this protein?
Circulin-A, CIRA.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: ISPG_AZOVD
Sequence: MHSESPIQRRPSRKIWVGPVAVGGDAPISVQSMTNTDTHDVEATVAQIRRLEAAGADIVRVSVPDMDAAEAFGRIKQQVQLPLVADIHFDYQIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPQALVESALRHVEHLDRLDFQNFKVSVKASDVFMAVAAYRLLAGQIEQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRVSLAADPVEEIKVGFDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELETRLEDLLVPLDVAVIGCVVNGPGEAKEAHVGLTGGTPNNLVYIDGKPAQKLGNENLVDELERLIRRKAAEKAAADASLIVRS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: LPXH_BORBR
Sequence: MNKLALQGPLWLASDLHLGPATPATAEAFLGLLQAAADEASALLLPGDIFDAWIGDDVIRAAPPWLAAVLQGIRAAAGRIPVYLGRGNRDFLIGQELADALGAHLLPEPVLLETDYGRILLTHGDEYCTDDSAYQQFRAMVRNPQWQAQFLAMSIPERLAMAEQARGESQAANQAKSMEIMDVNPASVEAALREADVDVLVHGHTHRPARHVLSVDGRKRERWVLPDWDCDHADPPRGGWLVIDRDGLQCFDLVEDED
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PG047_VACCA
Sequence: MPIFVNTVYCKNILALSMTKKFKTIIDAIGGNIIVNSTILKKLSPYFRTHLRQKYTKNKDPVTRVCLDLDIHSLTSIVIYSYTGKVYIDSHNVVNLLRASILTSVEFIIYTCINFILRDFRKEYCVECYMMGIEYGLSNLLCHTKNFIAKHFLELEDDIIDNFDYLSMKLILESDELNVPDEDFVIKWYIKRRNKLGNLLLLIKNVIRSNYLSPRGINNVKWILDCTKIFHCDKQPRKSYKYPFIEYPMNMDQIIDIFHMCTSTHVGEVVYLIGGWMNNEIHNNAIAVNYISNNWIPIPPMNSPRLYASGIPANNKLYVVGGLPNPTSVERWFHGDAAWVNMPSLLKPRCNPAVASINNVIYVMGGHSETDTTTEYLLPNHDQWQFGPSTYYPHYKSCALVFGRRLFLVGRNAEFYCESSNTWTLIDDPIYPRDNPELIIVDNKLLLIGGFYRESYIDTIEVYNHHTYSWNIWDGK
What is the function of this protein?
Might have a role in the suppression of host immune response.
What are the official names of this protein?
Immune evasion protein OPG047, Kelch repeat protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG047 family.