PharMolix/UniProtQA huggingface dataset:
Protein: LPP_RAT
Sequence: MSHPSWLPPRSTGEPLGHVPARMETTHSFGTPSISVSTQQPPKKFAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLEDPGTIPSGSGHFPPPPPLDEGAFIVQRGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRAPPGSSSSIASPPVSTPVTGHKRMVIPQQPPLTATKKSATKPQAIPIPVTPIGTLKPQPQPVPASYSTASTSSRPAFNVQVKSAQPSTHYMTGSSSGQMYGPGSRSYNTQQVPLSAQCPPPTTCAGTDYAYIPPSGQQAESGFGYTSNQGRYFEPFFAACPSYGGRNEADPAYGQQVQPNTWKREPGYAAPGAGNQNQPGMYSVSGPKKTYITDPVSAPCAPPVQPKERLVKNQKVLQNVVDDRVHGLRKSGFPAPMGPPSVPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCMVCDIKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKSCNSARIRVLTAKASTDL
What is the function of this protein?
May play a structural role at sites of cell adhesion in maintaining cell shape and motility.  In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription.  May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion.  Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus (By similarity).
What are the official names of this protein?
Lipoma-preferred partner homolog.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites.
Protein: GLS24_STRPM
Sequence: MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLGVNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVEEEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKASVDNGVEKLQDQKAEPRVK
What are the official names of this protein?
Stress response regulator gls24 homolog.
What is the protein family that this protein belongs to?
Belongs to the asp23 family.
Protein: CCDC8_HUMAN
Sequence: MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAEFRERLTQFLEEEGRTLEDVARIMEKSTPHPPQPPKKPKEPRVRRRVQQMVTPPPRLVVGTYDSSNASDSEFSDFETSRDKSRQGPRRGKKVRKMPVSYLGSKFLGSDLESEDDEELVEAFLRRQEKQPSAPPARRRVNLPVPMFEDNLGPQLSKADRWREYVSQVSWGKLKRRVKGWAPRAGPGVGEARLASTAVESAGVSSAPEGTSPGDRLGNAGDVCVPQASPRRWRPKINWASFRRRRKEQTAPTGQGADIEADQGGEAADSQREEAIADQREGAAGNQRAGAPADQGAEAADNQREEAADNQRAGAPAEEGAEAADNQREEAADNQRAEAPADQRSQGTDNHREEAADNQRAEAPADQGSEVTDNQREEAVHDQRERAPAVQGADNQRAQARAGQRAEAAHNQRAGAPGIQEAEVSAAQGTTGTAPGARARKQVKTVRFQTPGRFSWFCKRRRAFWHTPRLPTLPKRVPRAGEARNLRVLRAEARAEAEQGEQEDQL
What is the function of this protein?
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity.  It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696).  Required for localization of CUL7 to the centrosome (PubMed:24793695).
What are the official names of this protein?
Coiled-coil domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: INV3_DAUCA
Sequence: MARTKILVFSSDSSLFLLSIFSFIFLNINGVDSTHRVFPELQSISAVDVKLVHRTGYHFQPQKHWINDPNGPMFYKGYYHLFYQYNPKGSVWGNIVWAHSVSKDLINWIALEPAIFPSKPFDQYGCWSGSATILPGNKPVILYTGIVSPDPENAQVQNYAVPANYSDPFLREWVKPDNNPLVGVHTENPSAFRDPTTAWFDGGHWKMLVGSSRKHRGIAYLYRSKDFKKWKRSPHPIHTKAETGMWECPDFYPVSPRSEDGLDNSKMGRGIKHVLKVSLNSTRYEYYTIGRYNRVRDFYVPDNTSVDGWAGLRYDYGNFYASKTFYDPIKKRRILWGWANESDSQIDDVQKGWAGIQLIPRRIWLDPSGRQLVQWPIEEVEGLRGSELHMRNQKLDMGVHVEVTGITAAQADVDATFSFKSLDKAESFDPEWINLDAQDVCDSMGSTIQGGLGPFGLLTLASKDLEEYTPVFFRIFKAEDQKLKVLMCSDAKRSSLAEGLYKPSFRGFVDVDLSDKKISLRSLIDNSVVESFGAQRKNLISSRVYPTLAIYNNAHLFVFNNGTEPITVDNLDAWSMNSPSEMN
What is the function of this protein?
May play an important role in phloem unloading and in stress response.
What are the official names of this protein?
Beta-fructofuranosidase, insoluble isoenzyme 3, Cell wall beta-fructosidase 3, Invertase 3, Sucrose hydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Ionically bound to the cell wall.
Protein: CCMA_CUPPJ
Sequence: MPTPSSGLSCNGVAVGPVLRANDLAFSRGGRPVFTGIDFSVSAGGVIQVVGPNGSGKSSLLRVLSGLLQPASGSVSWLGKCVRAGDPAYLQSLAYVGHADGIDTDLTADEHLRYAARLTGLHATNETVRVALARLGIAKTMHVPIRTLSQGQRRRVALARLALVWRALWLLDEPLTSLDDESAACFHDLLDEHLRDGGMAVIATHRLLPGGGEVLQLGGAHALPPA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FADS2_DANRE
Sequence: MGGGGQQTDRITDTNGRFSSYTWEEVQKHTKHGDQWVVVERKVYNVSQWVKRHPGGLRILGHYAGEDATEAFTAFHPNLQLVRKYLKPLLIGELEASEPSQDRQKNAALVEDFRALRERLEAEGCFKTQPLFFALHLGHILLLEAIAFMMVWYFGTGWINTLIVAVILATAQSQAGWLQHDFGHLSVFKTSGMNHLVHKFVIGHLKGASAGWWNHRHFQHHAKPNIFKKDPDVNMLNAFVVGNVQPVEYGVKKIKHLPYNHQHKYFFFIGPPLLIPVYFQFQIFHNMISHGMWVDLLWCISYYVRYFLCYTQFYGVFWAIILFNFVRFMESHWFVWVTQMSHIPMNIDYEKNQDWLSMQLVATCNIEQSAFNDWFSGHLNFQIEHHLFPTVPRHNYWRAAPRVRALCEKYGVKYQEKTLYGAFADIIRSLEKSGELWLDAYLNK
What is the function of this protein?
Fatty acid desaturase with bifunctional delta-5 and delta-6 activities.  Component of a lipid metabolic pathway that catalyzes the biosynthesis of polyunsaturated fatty acids (PUFA) with preference toward n-3 substrates and Delta-6 function.
What are the official names of this protein?
Acyl-CoA 6-desaturase, Delta(5)/Delta(6) fatty acid desaturase, D5D/D6D fatty acid desaturase, Delta-5/Delta-6 fatty acid desaturase, Fatty acid desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYSH_BACAN
Sequence: MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD63_HUMAN
Sequence: MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM
What is the function of this protein?
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades.  Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases.  Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2.  Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2.  Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes.  Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking.  May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
What are the official names of this protein?
CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, LAMP-3, Lysosome integral membrane protein 1, Limp1, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-30.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
Protein: LIPA_MOEAP
Sequence: MRVSLRSITSLLAAATAAVLAAPATETLDRRAALPNPYDDPFYTTPSNIGTFAKGQVIQSRKVPTDIGNANNAASFQLQYRTTNTQNEAVADVATVWIPAKPASPPKIFSYQVYEDATALDCAPSYSYLTGLDQPNKVTAVLDTPIIIGWALQQGYYVVSSDHEGFKAAFIAGYEEGMAILDGIRALKNYQNLPSDSKVALEGYSGGAHATVWATSLADSYAPELNIVGASHGGTPVSAKDTFTFLNGGPFAGFALAGVSGLSLAHPDMESFIEARLNAKGQQTLKQIRGRGFCLPQVVLTYPFLNVFSLVNDTNLLNEAPIAGILKQETVVQAEASYTVSVPKFPRFIWHAIPDEIVPYQPAATYVKEQCAKGANINFSPYPIAEHLTAEIFGLVPSLWFIKQAFDGTTPKVICGTPIPAIAGITTPSADQVLGSDLANQLRSLNGKQSAFGKPFGPITPP
What is the function of this protein?
Hydrolyzes triglycerides, with a preference for substrates with short-chain lengths (C4 to C8).  Has the highest activity with tributyrin (C4), followed by tricaproin (C6) and tricaprylin (C8).  Can also hydrolyze vinylacetate (C2) and triolein (C18), but with lower efficiency.  Has no activity with tripalmitin (C16).
What are the official names of this protein?
Lipase A, CalA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: DUT_PSEPW
Sequence: MHALQAKILDPRLGSEFPLPQYATPGSAGLDLRALLKEDTVLEPGQTLLIPTGLSIYIGDPGLAAMILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSCWNRGNTPFTIAVGERIAQLVLVPVVQAHFEVVEAFDESQRGTGGFGHSGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TULP_DROSI
Sequence: MEAYIRQKRASPGMVQASDLQINRPMSGMRSNSRELHAYDGPMQFISSPQNPDQILTNGSPGGINPVAMNTSRNHSNNMRSLSTINQEADLIEEISSHELEDEESSPVTVIEQHQQSASHSANSTQSQKPRARQHSFSDNLDEDDYTNRNVAGAAPVRPAGMASSPYKDATLDGSSNGTGNGTGGESEGDVIGNIDQFVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNGNKESTESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE
What are the official names of this protein?
Protein king tubby.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BRMS1_RAT
Sequence: MPIQPSGKETEEMEAEGDSAAEMNGEADESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQQSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLLGELQERIQRLEEDRQSLDISSEWWDDKLHSRGSSKTWDSVPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQKRKADGP
What is the function of this protein?
Transcriptional repressor.  Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'.  Promotes HDAC1 binding to promoter regions.  Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B.  Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity).
What are the official names of this protein?
Breast cancer metastasis-suppressor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: YACG_ACTP2
Sequence: MSETIVNCPTCNQDVIWKPESKYRPFCSERCQLIDLGEWANEEKRIAAVENDVMTSDLEGHY
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: CP17A_MACFA
Sequence: MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQTIDISFPVFVAITNVISLICFNISYKNGDPELKIVHNYNEGIIDSLGKESLVDLFPWLKVFPNKTLEKLKRHVKTRNDLLTKIFENYKEKFHSDSITNMLDVLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQAWREAQAEGST
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: LECA_IRIHO
Sequence: YDKVEFHITGXTKDTYSAFIQSLRTHLS
What is the function of this protein?
Gal / GalNAc-specific lectin.  Agglutinates both native and trypsin-treated rabbit erythrocytes but not human erythrocytes irrespective of blood group type.
What are the official names of this protein?
N-acetyl-D-galactosamine-binding lectin subunit A, A-disaccharide-binding lectin subunit A, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family.
Protein: DCUP_GRAFK
Sequence: MIKNDLLLKALKGESVERPPVWMMRQAGRYLPDFMKLKEKYDFFTRCRTPELATEITVMPIRQIGPDAAILFSDILVVPQAMNIEVEMKPGVGPWLPNPIDSPKKVEQVIVPDVNEELGYVFEAIKMTKQELNDEVPLIGFAGSPWTILCYCVQGQGSKTFDKAKRFCFMNPIAAHTLLQKITDTTIAYLKEKVKAGVDAVQLFDSWGGLLEPKDYQEFSWKYMQQIIEALKDEVPVIAYGKGCWFALDKMAKSGAAALGVDWTCEARNARYLSGGEITLQGNFDPARLYSKPIEIKYMVNDMIKAFGKDRYIANLGHGILPNIPVDNAKAFVDAVKEYKE
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_FLAJ1
Sequence: MAKEISKVVKLQVKGGAANPSPPVGPALGAAGVNIMEFCKQFNARTQDKPGKICPVQITVYKDKSFDFVVKTPPAAVQLMEAAKLKSGSGEPNRKKVASVTWEQIRTIAEDKMPDLNAFTIEKAMSMVAGTARSMGITVSGDAPF
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: GALT5_MOUSE
Sequence: MNKIRKFFRGSGRVLAFIFAASVIWLLFDMAALRLSFSEINAGLLKEDIIRREHTGFRVEPDQVKVLYTSIRGMGLPRNGAWGKENFRKAENHELKVEENMDQVQRKGKMQNLLGRRKAVPLWHLAHLQTLPVTIPMQKTQGRDSKPEVSSQYMMSKWMTVLESEKTPFTASRGVPLTKIAGRTETFDKKQEAPQNYNVSSDTSKQASERTLNMTISVKTDRSKQKSQTVTKLRMHFASPPILKSEEVTVIKKAEAQSKDLKHEALKALPLLKFIADMGHLKNQSTNETQLGRLPEDDAAKVAPGKKLNFSESHVVIITKEEELKTDTKEVPNSKTQTVFPKLLGGSPHKQIPRNQSKTSSSPPALKKAVSQSKPTISGGLHTARSNLTAKAPTVGYQQSHANIPENPGMHHVFRIDVTLSPRDLNAPGQFGRPVVVPPEKKKEAEQRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHNDLPTTSIIMCFVDEVWSALLRSVHSVLNRSPPHLIKEILLVDDFSTKEYLKADLDKYMSQFPKVRILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLNRKKVACPVIEVINDKDMSYMTVDNFQRGVFTWPMNFGWKTIPPDVVAKNGIKETDIIRCPVMAGGLFSIDKSYFYELGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMKTVERNLVRVAEVWLDDYRELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLDNVFPDLKAPVVRASGVLINMALGKCVSIENITVTLEDCDGSSQLQQFNYTWVRLIKHGEWCVAPIPEKGSLTLYHCDNRNNRLKWLHKSASAFHPELVDHIVFENYQQLLCMEGNFSQKTLKLAACNPMELQQKWKFEKYYEV
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2 or Muc1b substrates (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 5, Polypeptide GalNAc transferase 5, GalNAc-T5, pp-GaNTase 5, Protein-UDP acetylgalactosaminyltransferase 5, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PEPE_ECO8A
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODJ_RHILV
Sequence: MGVATLPAGGLNWLAVWRRNYLAWKKAALASILGNLADPVIYLFGLGAGLGVMVGRVDGVSYTAFLAAGMIATSAMTAATFETIYAAFGRMQGQRTWEAMLYTQLTQGDIVVGEMAWAATKASLAGTGIGIVAAMLGYTHWLALLYALPVIAITGLAFASLGMVVTALAPSYDYFIFYQTLVITPMLFLSGAVFPVDQLPVAFQQIAAFLPLAHSIDLIRPTMLGQPIANVCLHIGVLCIYIVVPFLVSTALLRRRLMR
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit encodes the transporter (By similarity).
What are the official names of this protein?
Nodulation protein J.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF_STRU0
Sequence: MSAQDKIIKASHLITMDDIIREGNPTLRKEASEVSLPLSDEDIILGEKMMQFLKHSQDPVMAEKLGLRGGVGLAAPQLDISKRIIAVLVPNMEDSEGNPPKEAYSLQEIMYNPKIVAHSVQEAALADGEGCLSVDRLVEGYVVRHSRVTVDYYDKKGDKHRIKLKGYNAIVVQHEIDHINGIMFYDRINSQNPFAIKEGMLIIE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL28_RALSO
Sequence: MARVCQVTGKAPMVGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVSLRVSNAGLRLIDKKGIDEVLADLRARGEV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: Y8495_DICDI
Sequence: MISYEYCDSSDSFYFNDIQDFDFNPWIEVKSVSEKGRCVFSKKFIPKGTMVFRDIPYAAIVDNQFKRNICTTCFKILLESNRHNFQTCPSCFQVNYCSNYCKQYSKIETKHTELECKWIQDFTVSFKHQMAEDDRNIVLLVLKILARRIHEKQSTIFHNKPLTTNTFETCTSNNNNIDLLPMIPNDIPDLIDHLDDYFINSKNNNEFENEEEEEEEQEQKGEGEQEENENNENNEKVKKKVIIIDDNEKEKEEIKKFNKIWKNDFKRLINIAKVIQIIIDDSIDSLENIKCDYGFVDNQGDTEMVDNSIDPKGLDKLVDNLSSSDLNILRLLCKIRANYFGLWNSAYKPIPLNSIDDDDDDNNNNKEKPNNDYLWCGSGVYLKLSLFNHSCFPNCTTLIEYNINKKNSNNNNGNNGNNNSYGDTNQLTISIITLRDIEENQELLITYIPLNQKINDRVKSLKSNWLFQCDCKRCHFEKINENQTEKIYKDSCCTNQKCSGGLLIPLEQNSTQGICRVCKNTYTLPTVFYPLK
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
SET and MYND domain-containing protein DDB_G0288495.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: NUBP2_BOVIN
Sequence: MEAAAEPGNLAGVRHIVLVLSGKGGVGKSTISTELALALRHAGKKVGILDVDLCGPSIPRMLRAQGRAVHQGDSGWVPVFVDREQSISLMSVGFLLEQPDEAVVWRGPKKNALIKQFVSDVAWGQLDYLLVDTPPGTSDEHMAVVDALRPHSPLGALVVTTPQAVSVGDVRRELTFCRKVGLRVIGLVENMSGFVCPHCSECTNVFSKGGGEELARHAGVPFLGSVPLDPELTRSLEDGRDFIQDFPDSPAFPALSSIAQKILSETPAGLS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Negatively regulates cilium formation and structure.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2, Nucleotide-binding protein 2, NBP 2.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Enriched at the centrosomes during mitosis. Enriched in centrioles of microtubule asters during prophase, prometaphase and telophase stages of mitosis (By similarity). Localized at centrioles and in the nucleus at interphase (By similarity). Colocalizes with nubp-1 at prometaphase (By similarity).