PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_DAUCA
Sequence: MVTIRADEISKIIRERIEEYNREVKIVNTGTVLQVGDGIARIHGLDEVMAGELVEFQEGTVGIALNLESTNVGVVLMGDGLLIQEGSSVKATGRIAQIPVSEAYLGRVVNALAKPIDGRGEISASEYRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEFFMYRKRHTLIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLGSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLAVEEQIMTIYTGTNGYLDSLEIGQVRKFLVELRTYLKTNKPQFQEIISSTKIFTEEAEALLKEAIQEQMERFILQEQV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RASLC_MOUSE
Sequence: MSSVFGKPRAGSGPHSVPLEVNLAILGRRGAGKSALTVKFLTKRFISEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDTPRNCERYLNWAHAFLVVYSVDSRASFEGSSSYLELLALHAKETQRGYPALLLGNKLDMAQYRQVTKAEGAALAGRFGCLFFEVSACLDFEHVQHVFHEAVREVRRELDKSPLARPLFISEEKTLSHQTPLTARHGLASCTFNTLSTASLKEMPTVAQAKLVTVKSSRAQSKRKAPTLTLLKGFKIF
What are the official names of this protein?
Ras-like protein family member 12.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
Protein: DER_ECOSE
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: Y2583_STAAE
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGRFSRKSMVYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein NWMN_2583.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H32_TETPR
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PSBZ_MICAN
Sequence: MSIVFQFFLIALVLFSLLMVIGVPVAYASPQNWDQSKPLLYVGSAIWAILVVAVAILNFLVI
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: RL7_SYNY3
Sequence: MSAATDQILEQLKSLSLLEASELVKQIEEAFGVSAAAPVGGMVMAAAAAAPAEAAEEKTEFDVILEEVPADKKIAVLKVVRTITGLGLKEAKELVESTPKAIKEATGKDDAEAIKKQIEEAGGKAAVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DAPAT_DEHM1
Sequence: MKLSKRIENLPPYLFVQISKKIAEKRAKGEEVISFAIGDPDLPTPKHILAELCKAAEDPANHRYPETEGLPVLRKAMAEWYEKRFGVKLNPDTEVLPLIGSKEGIGHAAWCFLDPGDVALVPDPAYPVYAISSQLAGAEVFYMPLNKENNFLPDFNAIPQDVLSKAKILWINYPNNPTGAVAGLDFFKEAAEFAAKHNLAVCHDGPYSEIAFDGYRPVSFLEADGAKEVGIEFHSLSKSYNMTGWRIGMAVGNAKMIDALRRFKSNLDSGIPQAIQLMAIAALNGSQDVISQNCAVYQRRRDRLVEALRNIGMEVTAPKASLYIWAPVPEGYTSASFATELLDKTGVVVTPGTGYGTSGEGYIRLSLTVPDEQLEKGIAKLANFKSQA
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: SELO_SALTY
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDELAQQLAIPASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVPEKYALWFEEVAARTGRLIAEWQTVGFAHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNVLLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDRYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHEVLRQPFTDRDDDYARRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PHNW_SALNS
Sequence: MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNIGVVEQIRQQLTELATASEGYTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGARMVEMAGLMGIAHHAYDCGEVARPDVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAHRYGKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKLAACKGHSRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQALKELAKEGGVAARHQRYQQNQRSLVAGMRALGFNTLLDDELHSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYPGKVSQSDCFRIGNIGEVYAADITALLTAIRTAMYWMK
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: FLS_PETCR
Sequence: MEVERVQAISKMSRCMDTIPSEYIRSESEQPAVTTMQGVVLQVPVIDLGSSNNTEENLVELIAEASREWGIFQVVNHGIPDDAIAKLQKVGKEFFELPQQEKEVIAKPEGYQGVEGYGTKLQKELGGKKGWVDHLFHIIWPKSAVNYNFWPNNPPLYREANEEYAVALRGVVDKLFEALSLGIGLEKHELKKASGGDDLIYMLKINYYPPCPRPDLALGVVAHTDMSAITILVPNEVQGLQVHKDDHWYDVKYIPNALIIHIGDQIEIMSNGKYKSVYHRTTVNKDKTRMSWPVFLEPPPELLTGPISKLITDENPAKFKTKKYKDYVYCKLNKLPQ
What is the function of this protein?
Catalyzes the formation of flavonols from dihydroflavonols.  Acts on (2S)-naringenin and (+)-trans-dihydrokaempferol to produce kaempferol and on (2R)-naringenin to produce (-)-trans-dihydrokaempferol.
What are the official names of this protein?
Flavonol synthase/flavanone 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PETN_NICTO
Sequence: MDIISLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: RS7_CHLT2
Sequence: MSRRHAAEKKVIPGDPVYGSVVLERFINKVMLHGKKSIARKIVYGALERFAKRLGLENPLEGFEEALENAKPILEVRSRRVGGATYQVPVEVAPDRRSCLAMQWIIKHARSKPGKCMEVGLANELIDCFNKQGATIKKREDTHRMAEANKAFAHYKW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CWC26_CANGA
Sequence: MSLHDYLLKEYGPSDRKKKSKKVDSKSTAQKPNNEDVNSNANNPLRDNSEKSLWLSHGVNNIPGAPLSDNLTNKQKNGINIEPPSRTVLEPKTHNIETVFRNAQGHKIDVEAKTLDSDSGKRNSQEERIRILNMGEIQLAGLDGVSTISSKYTAEIRDNDPATEFDHNKGVNHQKISPLGRKLYAGTATENRFGILPGNKWDGVDRSNGYEKKWFKRQGELAESKIQEFTNSEDY
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC26.
What is the protein family that this protein belongs to?
Belongs to the CWC26 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MURQ_CLOBJ
Sequence: MTNISLDKLVTESRNENTKNIDRVETLEMLKMINNEDKKVAEAVEKELIHIAKAVDKIGEAFLNGGRLIYVGAGTSGRLGVLDASECPPTYGVSYDLVRGIIAGGESAMFKAREGAEDSKKLCIKDLKNINFGKNDILAGIAASGRTPYVIGGLEYANGIGATTISVTCNPESEMSKIANISIAPVVGPEAITGSTRMKAGTAQKMVLNMLSTGAMVKTGKVYGNLMVDLKATNEKLVERAKRIVMQATGSKREQVEKILKETNFDVKLSIFMIESSLDKIKAKEILDKNKGYIVEAIKEIS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RL21_ACIB3
Sequence: MYAVIQSGGKQHRVVEGETLKVELLKAESGATITFDDVLMVVNGDNIQIGAPVVAGAKVTAEVIGHGRHDKIRIIKMRRRKHYRKQQGHRQWFTELKITGISG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TRMB_LISMF
Sequence: MRVKHKPWAKDRLEEFPAIYIKNPEDFKGQWREVFGNDNPVHIEIGSGKGQFISGMAKANPEINYIGIEMIESVLVSALDKAIEADVSNLRLVARDAKLLEECFEKGEIAQIYLNFSDPWPKKRHTKRRLTNPTFLTIYERLLPEAGEIHFKTDNRSLFEYSLVAFSEYNMLLTFVSLDLHNSDYEGNIKTEYEEKFSAKGFPIYRLEAKFDRN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: EX7L_CHLAB
Sequence: MATSSPPQAVTTLTESIKNLLESNFCHIVVKGELSNVSLQPSGHLYFGIKDSKSFLNGAFFHFKSKYFDRRPKDGDSVIIHGKLTVYAPRGQYQIVAHALVYAGEGDLLQKFEETKKRLAAEGYFSIEKKQPLPRIPKCIGVITSPTGAVIQDILRILSRRCYQYKVLIYPVTVQGATAAKEISQAIEVMNRDKLVDVLVIARGGGSIEDLWAFNEEIIVKAIDASTIPIISAVGHETDYTLCDFAADVRAPTPSAAGEIVCQSSQEQIQIFKSHLRYLNAHAQQLLAGKAKQIQQWKRYLDHVDFFRPPHQSLDYLRVSIERSIQTTLSQSKQRYRQYTRWLQSDILQRMTYRLQDLWKMINLAFQNRLLALKHHCVHIKKNLVIHNTQQYRQRFDPCRDQIHRALSQRLGYFQQSLAHKQTLLKHFTTKINQLFIKETSALNLLKKRLNKAFVYTVCERREHFLYAKENLFLSLNHLVERHRAKYHTVSQQLISLNPKNVLKRGYAMLFDFNENSAIISAKSLHKHSCVRVRLQDGEATLTVTDVQNFETQEF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR1B_PULPI
Sequence: FMGGLIKAATKALPAAFCAITKKC
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacterium S. aureus ATCC 25923 and the Gram-negative bacterium E. coli ATCC 25726.
What are the official names of this protein?
Brevinin-1PTb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: NADE_THEKO
Sequence: MRALDYRAAIETITSFLSEKLEESGSGGFVIGISGGIDSATAAYLAAKAVGTENVLGLIMPYYENNDVEDAKLVCESLGIDYEVINIKPIVESFVSQLGFQPDKRSLGNIMSRTRMILLYAHANQLNRLVLGTSNRSEFLTGYFTKWGDGASDYAPLINLYKTEVWEIAKLLGVPGRIIQKKPTAGLWEGQTDEDELGISYRLLDEILWRLVDLKMPKEKIVEELGISVEKVEYVEGLVRRSEHKRRLPVGPEF
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: SASA_TRIV2
Sequence: MLKHDSMQVSQDQPIYSEAPLQLLLFVDGRPKSKQQVQRIRAYLKDLQAEYNFELQIIDVGQQPYLAEHFKLVATPALIKIHPEPRQILAGSNIITQLKNLWPRWQAAVDTYVKLQEDLQERVDDNGRVAQPTSTINSVAVSAELLRLSDEIFNLKQEKEKLLEQLQFKDRVIAMLVHDLRNPLTAAAIAIETLQSNYNPDIGQFQRLKPALVVNLLRQARTQAKTIDKMIADLLQVGRGTDTELIIIPQKTEIGLLCLEVLGELRDRYTTKAQKVETDIPQDLPCVYADPERIRQVLINLLDNAIKYTPEGGTISIAGLHRTTQKVQFSIGDTGPGIPTDNRERIFENHYRLERDEAKEGYGIGLSLCQRIIRAHYGQIWVDSNPHGGAWFHFTLPVYPS
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: NUOD_HERAR
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAEQKTYLQSVPYMDRLDYVSMMCNEHAYVMSIEKMLNLEVPLRAQYIRVMFDEITRILNHLMWLGAHALDVGAMGVFLYAFREREDLMDCYEAVSGARMHAAYYRPGGVYRDLPDAMPQHKASIIRNAKAINKLNENRQGSLLDFIEDFTNRFPTYVDEYETLLTDNRIWKQRLVGVGVVSPERAMAMGFTGPMLRGSGIEWDLRKKQPYEVYDLLDFDIPVGTNGDCYDRYLVRVEEMRQSNRIIKQCVEWLRNNPGSVMTDNHKVAPPSRVDMKSNMEDLIHHFKLFTEGFHVPVGEAYAAVEHPKGEFGVYLISDGANKPYRMKIRAPGFPHLQGLDEMAKGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KAPR_HYPAT
Sequence: MSLPEAYQLEIQALNKQVLQTCPSDILQFCADFFNSRLATERAASISLFRDRGTPSPRFPPSPTNPHFGMMSSQFSSPFGANANPFGGSSSNPNPFGGSASPMSSSVMHRVVEEDESDNHLAPGGSLFSGAFGGDASTEAPPTLRAPPTTDSYPAQYNFSRRTSVSAESLKPSADGFDNWTPPYTDKTPEQVERLKYAIEGNFLFSHLDDEQSAQILGALVEKPIPARGIKVISQGDAGDYFYVVERGSFDVYVNDCGFIEPGPDGLGNKVGTIQAGGSFGELALMYNAPRAATIISAEGSCTLWALDRVTFRRILMESTFARRRMYENFLEEVPILSSLTPYERSKISDALETQKFAPGDVIIHEGDPGHSFYLLESGEAAAFKGEEQVLSYKKGDFFGELALLNDAPRAASVIATSDVKVATLGKNAFQRLLGPVEGLLRRTRYLGVKTGVEEMDPLHTQ
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, PKA regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
Protein: DAPF_BUCAI
Sequence: MDSYYKNKKKINFSKMHGLKNDFMVINCIKKNVFLTSHIIKKLSNRYTGIGFDQLLLVEKSNSLLTDFHYRIFNANGNEVEQCGNGARCFGLFLLLKGLTNKKKILISTKKKPLTIEFLTENMIKVNMNEPDFKFYNLSSLQNVLDNNFSIKLMNENLICNLVSIGNPHCIIKVQSVKNAPVNIIGDSIEKNPIFPEGVNVSFMEILNKKHIKLRVYERNVGETKACGSAACAAVAVGIAQKLLSDTVHVELLGGKLIIIWKGFGTPLYMVGPAKHVYDGYIYI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_HUMAN
Sequence: MWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINYSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDEPAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVMSTYLVAFVVGEYDFVETRSKDGVCVRVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAATEDLWESLENASGKPIAAVMNTWTKQMGFPLIYVEAEQVEDDRLLRLSQKKFCAGGSYVGEDCPQWMVPITISTSEDPNQAKLKILMDKPEMNVVLKNVKPDQWVKLNLGTVGFYRTQYSSAMLESLLPGIRDLSLPPVDRLGLQNDLFSLARAGIISTVEVLKVMEAFVNEPNYTVWSDLSCNLGILSTLLSHTDFYEEIQEFVKDVFSPIGERLGWDPKPGEGHLDALLRGLVLGKLGKAGHKATLEEARRRFKDHVEGKQILSADLRSPVYLTVLKHGDGTTLDIMLKLHKQADMQEEKNRIERVLGATLLPDLIQKVLTFALSEEVRPQDTVSVIGGVAGGSKHGRKAAWKFIKDNWEELYNRYQGGFLISRLIKLSVEGFAVDKMAGEVKAFFESHPAPSAERTIQQCCENILLNAAWLKRDAESIHQYLLQRKASPPTV
What is the function of this protein?
Aminopeptidase with broad substrate specificity for several peptides.  Involved in proteolytic events essential for cell growth and viability.  May act as regulator of neuropeptide activity.  Plays a role in the antigen-processing pathway for MHC class I molecules.  Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors.  Digests the poly-Q peptides found in many cellular proteins.  Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
What are the official names of this protein?
Puromycin-sensitive aminopeptidase, PSA, Cytosol alanyl aminopeptidase, AAP-S.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: YD071_YEAST
Sequence: MLVRDIAAEVYFAQSVCFSFSAFSLFRSFLATAPALYIKSLPNNKVAETSANVDHFATVSLCTSNEKLALVAPHELLEPLPNIIAHLFESFSAALLLKVCVLSKCSCSCSPSMRKHLRVSPFLF
What are the official names of this protein?
Putative uncharacterized protein YDL071C.
Protein: DACT2_HUMAN
Sequence: MWTPGGPPGSAGWDRRRLGARLRAAFAGLQELQGLRATQQERVRGALALQPPPAPAAPCGPHGLHGPEQQLEAALAALQEQLSRLRQQDIGLKTHLDQLDLQISKLQLDVGTASGEALDSDSRPSSGFYEMSDGGSCSLSTSCASVCSDHISPSLGSLLPVAQAHKARPSMGDWRPRSVDETTVPAWRPQATEEGARPPGSVEDAGQPWGTFWPRPVSTGDLDRALPADTGLQKASADAELLGLLCQGVDIPLHVPDPKYRQDLVSQGGREVYPYPSPLHAVALQSPLFVLTKETPQRGGPSFPRESPRGPAGLNTIQTGPVLEAGPARARAYIDRLLHLWGRETPAKGSEGEQGPLRHAASPSPQRQGGWSTDGGGRLLVFAPGREDEGGPAQSRGAGRGGPQQQGYMPLEGPQQSGSLPEEGSKPSNSCVLRETMVQASPSSKAQQTPSAQDYGRGNIISPSRMLDKSPSPASGHFAHPSFAASLKMGPPKSKAEKIKRSPMDKVLRFARQPLLLLDRPEGAHAAPQPSLEWDPAHWPTGRGGLQRRPALAWEAPGRSCSESTLYPMPVLVPLAVAPQESHRTSAQALFPFEASLLTSVARRKHRRWQSTVEISARARLASCPESNLGPPRPVARRAGGPLARGRPSLVRQDAYTRSDSEPSKHSAECDPRFPSVIPETSEGESSDHTTNRFGDRESSSSDEEGGAQSRDCDLALGYVAAGHAELAWTQEAPVSSGPLLSPVPKLCRIKASKALKKKIRRFQPTALKVMTMV
What is the function of this protein?
Involved in regulation of intracellular signaling pathways during development.  Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1.  May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character.  May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity).
What are the official names of this protein?
Dapper homolog 2, Dapper antagonist of catenin 2.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
Protein: PIN1_THEAN
Sequence: MIRNFLNFLWNNTSLRFLIINTIIFAMDKVRCAHLLLKHTGSRNPVNRNTGMAVTRTKEEAVSEMKGYLEMLRKSDNLDQEFRRLATAKSECSSARKGGDLGFFDRNTMQKPFTEASFKLEVNEISDLVETDSGVHLIYRIA
What is the function of this protein?
Peptidyl-prolyl cis/trans isomerase (PPIase) that acts as a key virulence factor by promoting host leukocyte transformation.  Binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs in a subset of proteins, resulting in conformational changes in the proteins.  Promotes host leukocyte transformation by binding to phosphorylated host FBXW7, disrupting dimerization and promoting FBXW7 autoubiquitination and subsequent degradation.  Degradation of host FBXW7, leads to stabilization of JUN, which promotes cell transformation.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, TaPIN1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: COBS_SALSV
Sequence: MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLILGGVSGLIFILLQSWCGIPLAALFCILALALLTGGFHLDGLADTCDGIFSARRRERMLEIMRDSRLGTHGGLALIFVLLAKILVVSELALRGTPMLAALAAACAAGRGSAVLLMYHHRYARDEGLGNVFIGKVSGRQTCITLGLAVIVATVLLPGMQGLAAMVVTLAAIFILGQLLKRTLGGQTGDTLGAAIELGELIFLLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQJP_BACSU
Sequence: MTTEDVIAIRVPTPFAVGDVIVYLVKGDALTLIDAGPNTKEAARALQEQLAAVNVKLSDIEQVVLTHHHADHAGLLDVFSDEIEVIGHTFNEPYISQNQAFMDWQKRFFQKLLPELGVPFDTGKAEKLIRSAYAFSCTRSLTKSIREGMGIDGLEGWSVLEMPGHAESHIVLFHEKSGRMLGGDLLLANSSSNPILEAPKAGDVRSKPLVDYQRSLRRLSQLDPTIVFPGHGEPITSVQALIEKRFDKQRNRTEDVRRMLDEKPMTAFQVCQQLFPAVYEKELFLTMSETAGHLDVLEAEEAITSYWEGNTVYFKTMKR
What are the official names of this protein?
Probable metallo-hydrolase YqjP.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.