PharMolix/UniProtQA huggingface dataset:
Protein: LUXS_STRZP
Sequence: MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: TPC1_NEUCR
Sequence: MSGKAERLKDEGSRLQVTAAGATAGLISRFVIAPLDVVKIRLQLQHHSLSDPLLHQRRAEIIGGGPVYKGTLPTIRHILRTEGLTGLWKGNIPAELLYVSYAAVQFTTYRSITQFLQAAFPKDQNKQLPPSVESFIAGASAGGVATAVTYPLDLLRTRFAAQGVERVYPSLVQALKTIYASEGVTGYFRGLGPGLAQIIPYMGTFFCVYETLRPRLSKLELPYSSGSAVAGVLASVMAKTGTFPLDLVRKRIQVQGPTRGMYVHKNIPVYDGGMVKTVATIVRREGVRGLYRGLTVSLFKAAPASAVTMWTYERALKLYIRLGAAGPGRKEGV
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SLYX_ECO8A
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: Y032_SIFVH
Sequence: MGEENIELPEGNNKSETEKYIEDLINSIESELPKHVNYTTGIIVDDERNLLIIKNGKLHVGRDENNAKEIKEYVKDANAGYLINALYVLKQMLASYKDLWSGKIEREAKKALNEII
What are the official names of this protein?
Uncharacterized protein 32.
Protein: RSEP_SALTI
Sequence: MLSILWNLAAFIIALGVLITVHEFGHFWVARRCGVRVERFSIGFGKALWRRTDRYGTEYVIALIPLGGYVKMLDERAEPVAPELRRHAFNNKTVGQRAAIIAAGPVANFIFAIFAYWLVFIIGVPGVRPVIGEITPNSIAAQAQIAPGTELKAVDGIETPDWDAVRLQLVSKIGDQQTTVSVAPFGSDQRQDKTLDLRHWAFEPDKQDPVSSLGIRPRGPQIEPVLSEVQANSAASKAGLQAGDRIVKVDGQPLTQWMKFVTFVRDNPGKPLALEIERQGSALSLTLTPDTKSVNGKAEGFAGVVPKIIPLPEEYKTIRQYGPFSAILEATDKTWQLMKLTVNMLGKLITGDVKLNNLSGPISIAQGAGMSAEFGVIYYLMFLALISVNLGIINLFPLPVLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL
What is the function of this protein?
A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA.  Part of a regulated intramembrane proteolysis (RIP) cascade.  Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA.  This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA (By similarity).
What are the official names of this protein?
Regulator of sigma E protease, S2P endopeptidase, Site-2 protease RseP, S2P protease RseP, Site-2-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PBUA_PSEU4
Sequence: MSASRFMLRPLTRALLMHGATRTRLAGTGLGLALTLTAAPYVQAQEWTLNIPSQPLAQALQTLGQQTSLQIIYSPESLQGLRSTALNGRYQDDESLKAMLNGTGIRYQRDGNTVTVLGPATGSAMELAPTNVNASRLGATTEGSNSYTTGGVTIGKGVHSLKETPQSVTVMTRKMLDDQNLNTIEQVMEKTPGITVYDSPMGGKYFYSRGFRMSGQYQYDGVPLDIGSSYVQADSFNSDMAIYDRVEVLRGAAGMMKGAGGTAGGVNFVRKRGQDTAHTQLSLSAGTWDNYRGQVDTGGPLNDSGTIRGRAVVTEQTRQYFYDVGSRKDQIYYGALDFDLSPDTTLGLGFAWEDVDATPCWGGLPRYADGSDLHLKRSTCLNTAWNNQRSKRATYFADLKHQFNDDWSLKVAGVYSRNTQDMEYAFPSGAVPVGATATNTLMLGSIYDYDQRDYGFDAYVDGKFDAFGQQHELTIGANASRSHKDDFYAVAALPQRQNVLDPNHHIPQPDESYYLANASRGGPVDMHIKQYGAYSIARLKLADPLTLVLGSRVSWYKSDTDSVQYFRGEGTQVDTKSTETGQVTPFAGVLFDLNDNLTAYASYTDIFTPQGAYKTIDGSTLKPLVGQSYELGIKGEWFDGRLNSTFNLFRTLQKDAAQDDPRCEDSSCSINSGKVRAQGFEAEVSGEVIDRLQLLAGYTYTQTKVLEDADATQDGVVYNSYVPRHLLRVWGDYSLSGPLDRVTIGAGVNAQTGNYRTSPIGGDNIDGAGYAVWNGRIGYRIDDTWSVALNGNNLFDKRYYSTIGTEGFGNFYGDPRNFVMSVKADF
What is the function of this protein?
Specific receptor for the siderophore ferric pyoverdine (pseudobactin) M114.
What are the official names of this protein?
Ferric-pyoverdine M114 receptor PbuA, Ferric-pseudobactin M114 receptor PbuA.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: STX5_CAEEL
Sequence: MSDFHNIRSRRRIPEASSYSTVDFDYDPDQKNHTSAVAPTSFAYSSLTTVFNASASQLWNSAQEALVSSYDTAEGTESIDADRSKVVETLESLSIFGNPLDHIIITMPSRDRTSEFRATAKSYEMKAAANGIRPQPKHEMLSESVQFNQLAKRIGKELSQTCAKMEKLAEYAKKKSCYEERSQIDHLSSIVKSDITGLNKQIGQLQEFSKRRAGNMKNQNSGHIQLVVVGLQSKLANVGKDYQSVLEISTETMKAEKNRRDKFSSGAAVPMGLPSSSSGANVRSKLLQDDEQHGSSSIALDMGALSNMQSQQTMQQRDSSLEYAQARSNTMATIEGSISELGQIFSQLASLVSEQGEMITRIDSNVEDTALNIDMAHSELVRYLQNISKNRWLMIQVFGVLMVFFVVFVLFLT
What is the function of this protein?
Potentially involved in docking of synaptic vesicles at presynaptic active zones.
What are the official names of this protein?
Putative syntaxin-5.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: KAD_ECO8A
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCHNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_BURA4
Sequence: MPDRLVPATLARRDDGILVSPEYGELPRDASHARAHANRMLAGTGLPAHWRGRRTFTIVETGFGTGSRFLATWAAWRDDPARCERLHFVAIEPHPFARDDLRRAVSNFVADTTISENADALLDAWPMHVPGLHRLEFDAGRVVLTLAFGDAHDMLQRLVARADAFYLGNLASAAHGDVLSADVIRALARIAADGATYATHSHDDAVKHALEQTGFTSRDVEDGAGEPALRVGEYAPRWRMRRHEPPRALPVASREAIVIGAGLAGCAVVERLAARGWNITLIERHEQIASEASGNPAGVFHPLMTRDDNVASRLTRSGFLHALARWRALEEAGHAFARSTRGMIHLAESADDFARMRDAFDALGAPSDYVSLLDTDAARAHLNLPVAHGGLLFPHGGAVWPAGVCAAQIAAAGERVKLLAGTEVARLERDRDMWRAVDAASATLAEAPVVVLANAGDAVRLAGLRHVALQPVRGQLTLLPPGSTAPLPCPTIGDGYAVPLDDGTLLIGATFEPDDVDRTMRTAGHIENLERVRHLLPGLIGELPDVDTLRGRVAFRWVVADRVPVIGPLADEAQGVANARALSGAKARDLPRAAGLYGAFGYGSRGLVWAALGAELIASQLEGEPLPLERELVDAVDPARFLIRALRGRQIG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUER_VIBCH
Sequence: MNISQIAKLTSLTAKSIRLYEEKGLIIPPLRSESGYRTYTQQHVDDLLLIARCRRVGFSLDECKAMLTLANDPNRTSAAVRARAQEKWQEISRKLSELTMIKQQLEEWIASCPGDQGSDCPIIEQLKGHCCSNNKTKTP
What is the function of this protein?
Regulates the transcription of the copA and cueO genes.  It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CueR, Copper efflux regulator, Copper export regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_ECO27
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_GOSHI
Sequence: MAASFSVPSMIMEEEGRFETEVAEVQAWWNSERFKLTRRPYSARDVVALRGSLKQSYGSNEMAKKLWTTLKTHQANGTASRTFGALDPVQVTMMAKHLDSIYVSGWQCSSTHTTTNEPGPDLADYPYDTVPNKVEHLFFAQQYHDRKQREARMSMSREERARTPYVDYLKPIIADGDTGFGGTTATVKLCKLFVERGAAGVHIEDQSSVTKKCGHMAGKVLVAVSEHINRLVAARLQFDVMGVETVLVARTDAVAATLIQTNVDTRDHQFILGATNPNLRGKSLANMLAEGMAAGKNGPQLQAIEDNWLAIAQLKTFSECVMDAIKSMNITEDEKRRRMNEWMNHSSYDKCLSNEQAREIAERLGLQNLFWDWDLPRTREGFYRFRGSVMAAIVRGWAFAPHADLIWMETSSPDMVECTRFAEGVKSMHPEIMLAYNLSPSFNWDASGMTDEHMRDFIPRIAKLGFCWQFITLAGFHADALVTDTFARDFARRGMLAYVEKIQREERNNGVDTLAHQKWSGANFYDRYLKTVQGGISSTAAMGKGVTEEQFKETWTRPGAGNIGSEGNLVVAKARM
What is the function of this protein?
Involved in storage lipid mobilization during the growth of higher plant seedling.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratsysase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: ACTA_HUMAN
Sequence: MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NUOC_ROSDO
Sequence: MSEPLQELGNYIATKRADCVLAWDVTNKELNLDVTPSNIVGLVEFLKTDATCRFSTLIDITAVDYTGRAKRYDVVYHLLSMYQNHRVRLRVSIREDQMMPSVISVHPSANWFEREVFDMFGILFSGHPDLRRILTDYGFRGHPLRKDFPTTGYTEVRYDEAQKRVVYEPVSLVQEYRQFDFMSPWEGAEYILPGDEKKE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HUNB_LITFO
Sequence: HLRNHFGSKPHKCRKCNYSCVNKSMLNSHMKSHTNVYQYRCADCTYATKY
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPM1L_HUMAN
Sequence: MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ
What is the function of this protein?
Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
What are the official names of this protein?
Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL7_BAUCH
Sequence: MSLTKEQILEAVAKMSILDITELISMMEQKFGVSSINTIVPTSSPAETVEEKTEFDVVLTNIGANKIAVIKAVRGVISLGLKEAKDLVESAPITLKESISKDEAAALKKILEDAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: AAEX_ECOUT
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VA0E2_HUMAN
Sequence: MTAHSFALPVIIFTTFWGLVGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit e 2, V-ATPase subunit e 2, Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2, Vacuolar proton pump subunit e 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: MURC_XANOP
Sequence: MIRRLQDSGDLVRAFPRVHFVGIGGTGMSGIAEVMLTLGYEVSGSDNSDNVATRRLAKLGARVMRGHSAANVLGTDCVVVSSAIRDDNPELMEARSQRIPIMPRAAMLAELMRFRRGIAVAGTHGKTTTTSLAAAVLSEGGLDPTFVIGGQLLAAGANAKLGGGQWLVAEADESDGSFLRLNPLMAVITNIDADHLENYGNDFARIQAAFAEFLQRLPFYGLSLLCIDDPEVAALAGRTPRHVMSYGMSENADVRAEDVVQDGPRMRFTLRLPEGTTTPVTLALPGRHNVLNALAAAAIGWQLGVAPGTIARALENFAGIGRRFNDLGEVTTSTGARVRVVDDYGHHPRELEAVFAAARGGWPDKRLVVAFQPHRYSRTRDQFDAFAAVLSTVDALVLSEVYPAGEAPIPGADSRALARAIRARGRSEPVVVGQIASLAEVLPDVLQDGDLLLMMGAGDIGYVAQHIINNGFVGEPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRAT_BOVIN
Sequence: MKNPMLEAVSLVLEKLLFISYFKFFSSGAPGQDKAGNTLYEISSFLRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDKGRTQKVVSNKRLILGVIGRVASIRVDTVEDFAYGAEILVNHLDRSLKKKALLNEEVAQRAEKLLGITPYSLLWNNCEHFVTYCRYGTPISPQADKFCENVKIIIRDQRSVLASAVLGLASIFCLGLTSYTTLPAIFIPFLLWMAG
What is the function of this protein?
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (PubMed:9920938, PubMed:2722792).  Retinyl esters are storage forms of vitamin A (Probable).  LRAT plays a critical role in vision (Probable).  It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable).  Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity).
What are the official names of this protein?
Lecithin retinol acyltransferase, Phosphatidylcholine--retinol O-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the H-rev107 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum. Endosome, multivesicular body. Cytoplasm, perinuclear region. Note=Present in the rough endoplasmic reticulum and multivesicular body in hepatic stellate cells. Present in the rough endoplasmic reticulum and perinuclear region in endothelial cells (By similarity).
Protein: RS5_CICAR
Sequence: RSDPTQIEVKLFNRWSFDDVQLSDVSLIDYIGVVPSKHATYVPHTAGRYSVKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIIKHAMEIIHLLTDQNPIQVIVDAVVNSGPREDATRIGSAGVVRRQAVDISPLRRVNQAIYLLTTGAREAAFRNIKSIAECLADELINAAKGSSNSYAIKKKDEIERVAKANR
What are the official names of this protein?
40S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL23_SYNRU
Sequence: MSKRGRGGSSGNKFRMSLGLPVGAVVNCADNTGAKNLYVISSGVRGRLNRLPAAAVGDMVMATVKKGKPDLRKKVMPAVIVRQRKPWRRKDGVFMYFEDNAGVIVNPKGEMNPSAITGPIGKECADLWPRIASAANAIV
What are the official names of this protein?
60S ribosomal protein L23, L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y1659_METB6
Sequence: MPDYLVTLESAWYIKEAKTLDDAIGIAISEAGKRLNPSAKFVEVEAGMLACPFCERELSSAIVVADTALVGLILEMKVFRAESKEHASRIAKSVIGKALHEIPLKLLDVQEL
What are the official names of this protein?
UPF0212 protein Mboo_1659.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: CAR10_MOUSE
Sequence: MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLHREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPPPGAEEKEREPDGADLLSELRAENQRLTASLQELQEGLQQEMSRPGAAGSERILLDILEHDWREAQDSRQELCQKLHAVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRTQGGSCLKACASSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEPHTSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDFLNRSLAIRVSGWSPPAGLDPQDKSPDSMPGLGDRWSGAVVRRVLSGPGSARTEQKEPRAEGTGLEGAGLEAEAQQRTLPWNQSSTLPFLLDSKACHSFHEALDAWAKGPGAEPFYIRANFSLPERSDPHALCVKAQEILRLVDPAHKRRQEWFCTRVDTLTLRDLDRGTVPNYQRAQQLLEVQEKYLISSRHRSPRSNLKKRALGLVRPKPAGGTAGDSAEQLPAEPCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESLSGEEQCTSSAPGAPKAWPATAGLGSRIRAIQESVGKKHCLLELGARGVRELVHSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGSGSSSEA
What is the function of this protein?
Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR.
What are the official names of this protein?
Caspase recruitment domain-containing protein 10, Bcl10-interacting MAGUK protein 1, Bimp1.
Protein: RK22_CUCSA
Sequence: MIKTKKNRYEVYALGQHICMSPHKARRVIDQIRGRSYEETMMILELMPYRACYPILKLVYSAAANASHNMGFNERDLVISKAEVNQGTTVKKLKPRAQGRSYPIKRPTCSITIVLKNTSVNEEEFKRYQYTINQPGGLITKEKYTDMRCYDMYNNGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL28_SYNS9
Sequence: MSRVCQLTGTRANNGMAVSHSHIRTKKLQQANLQQRRLWWAEGNRWIKLRVTTRALKTIQKKGLGPYAKSLGINLAKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ACP_PROM2
Sequence: MSQEILEKVCSIVSEQLSVEAGEVKSDSNFQNDLGADSLDTVELVMALEEAFDIEIPDEAAEGIATVGDAVKFIEEKKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_THET8
Sequence: MERPLESYKKEAAHAAIAYVQDGMVVGLGTGSTARYAVLELARRLREGELKGVVGVPTSRATEELAKREGIPLVDLPPEGVDLAIDGADEIAPGLALIKGMGGALLREKIVERVAKEFIVIADHTKKVPVLGRGPVPVEIVPFGYRATLKAIADLGGEPELRMDGDEFYFTDGGHLIADCRFGPIGDPLGLHRALLEIPGVVETGLFVGMATRALVAGPFGVEELLP
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GTHB2_CLAGA
Sequence: MPASSYFLLFFFMNFFSPAQSYLLTHCEPVNETVSVEKDGCPKCLAFQTSICSGHCFTKEPVYKSPFSSIYQHVCTYRDVRYETIRLPDCRPGVDPHVTYPVALSCECSLCTMDTSDCTIESLNPDFCMTQKEFILDY
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-2, GTH-II-beta, Gonadotropin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYM1_BACHK
Sequence: MSIFIGGAWPYANGSLHLGHIASLLPGDILARYYRAKGENVLYVSGSDCNGTPIAIRAKQEGVTAKEIANKYHEEFERCFRNLGFTYDCYTRTDSEHHHETVQNVFLRLLEEGHIYKKTVEQAYCETCTQFLPDRYVEGVCPHCHEEARGDQCDACSAILDPLDLLEKKCKLCGSTPSIQETEHFYFALHTFQEQIKRAVEIAKQTGTWRDNAIQLTERYVKEGLLDRAVSRDLPIGVPIPVEGYEDKKIYVWIEAVTGYYSASKHWAEETGKDDREFWDGEAKTYYVHGKDNIPFHSVIWPAVLLGIGEGTIPRHIVSNEYLTVEKRKLSTSKNWAVWVPDILERYDPDSIRYFLIVNAPENRDTDFSWREFIYSHNSELLGAYGNFVNRTLKFIEKYYGGIMPKGSIDVELKDKIERLYKHVGEAIEQTKFKVALESIFDAVRFANKYFDERQPWKEREDDPVSCEETIYNCVYLIANFANLLEPFLPFSSERIRNTLSIVNRNWEPQHTLPSRIDSVQPLFERIDVKQIECELEKLYGAVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase 1, Methionyl-tRNA synthetase 1, MetRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.