PharMolix/UniProtQA huggingface dataset:
Protein: RS8_NITMU
Sequence: MSMSDPIADMLTRIRNAQLSEKTSVVMPASKLKAAIAQVLKDEGYVEDFIVHEAGGKSILDISLKYYAGRPVIERIERVSRPGLRIYKGSNKLPNVMNGLGVAIVSTSKGVMTERKARANGVGGEVLCIVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TWF2_MOUSE
Sequence: MAHQTGIHATEELKEFFAKARAGSIRLIKVIIEDEQLVLGASQEPVGRWDQDYDRAVLPLLDAQEPCYLLFRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDELFGTVKDDLSLAGYQKHLSSCAAPAPLTSAERELQQIRINEVKTEISVESKHQTLQGLAFPLQPEAQRALQQLKQKTVNYIQLKLDLERETIELVHTEPTNVAQLPSRIPRDAARYHFFLYKHTHEGDALESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFQLEIAKKIEIGDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGEDS
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin.  By capping the barbed ends of filaments, it also regulates motility.  Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.  May play a role in regulating the mature length of the middle and short rows of stereocilia.
What are the official names of this protein?
Twinfilin-2, A6-related protein, mA6RP, Twinfilin-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization. Isoform 2 found also along myofibrils in cardiomyocytes (PubMed:18837697). Localized in cochlea hair cells to the tips of the middle and short rows of stereocilia (PubMed:19955359).
Protein: PRRP2_ARATH
Sequence: MAASDQHRSRRHDESSSRPNKKKKVSRNPETNLLFNLNSCSKSKDLSAALALYDAAITSSEVRLSQQHFQTLLYLCSASITDISLQYLAIDRGFEIFDRMVSSGISPNEASVTSVARLAAAKGNGDYAFKVVKEFVSVGGVSIPRLRTYAPALLCFCEKLEAEKGYEVEEHMEAAGIALEEAEISALLKVSAATGRENKVYRYLHKLREYVGCVSEETLKIIEEWFCGEKAGEVGDNGIGSDVGMLREAVLNNGGGWHGHGWVGEGKWTVKKGNVSSTGRCLSCSEQLACVDTNEVETQKFVDSLVALAMDRKTKMNSCETNVVFSEFQDWLEKHGDYEAIVDGANIGLYQQNFVDGSFSLSQLESVMKELYRESGNNKWPLILLHKRRVKTLLENPTHRNLVEEWISNGVLYATPPGSNDDWYWLYAAAKLKCLLVTNDEMRDHIFELLGSTFFQKWKERHQVRYTFVKGNLKLEMPSPFSVVIQESEKGSWHFPVSCENNEESSRTWMCISRQSILDSPKSNGKIP
What is the function of this protein?
Endonuclease RNase P responsible for the 5' maturation of tRNA precursors (PubMed:22549728, PubMed:26655022).  Preferentially binds precursor tRNAs containing short 5' leaders and 3' trailers (PubMed:26655022).  Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA) (PubMed:22549728).
What are the official names of this protein?
Proteinaceous RNase P 2.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CR1L_RAT
Sequence: MEASSPLDPVGRLVAFCRGGVHLAVLLLFLSPSTLGQCPAPPLFPYAKPINPTDESTFPVGTSLKYECRPGYIKRQFSITCEVNSVWTSPQDVCIRKQCETPLDPQNGIVHVNTDIRFGSSITYTCNEGYRLIGSSSAMCIISDQSVAWDAEAPICESIPCEIPPSIPNGDFFSPNREDFHYGMVVTYQCNTDARGKKLFNLVGEPSIHCTSIDGQVGVWSGPPPQCIELNKCTPPHVENAVIVSKNKSLFSLRDMVEFRCQDGFMMKGDSSVYCRSLNRWEPQLPSCFKVKSCGAFLGELPNGHVFVPQNLQLGAKVTFVCNTGYQLKGNSSSHCVLDGVESIWNSSVPVCEQVICKLPQDMSGFQKGLQMKKDYYYGDNVALECEDGYTLEGSSQSQCQSDASWDPPLPKCVSQVICKLPQDMSGFQKGLQMKKDYYYGDNVALECEDGYTLEGSSQSQCQSDASWDPPLPKCVSRSNSGLIAGIFIGIIVLILFIIFSYWMIMKFKKRNSTNEKCKEVGIYLNSKEDSCVQPQSLLTSQENNSTSSPARNSLTQEV
What is the function of this protein?
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue.  Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.  Seems to act as a costimulatory factor for T-cells.  May play a crucial role in early embryonic development by maintaining fetomaternal tolerance.
What are the official names of this protein?
Complement component receptor 1-like protein, Antigen 5I2, Complement regulatory protein Crry.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MDM12_PYRTR
Sequence: MSIDINWDTITGGTEGSARAEKIRAFIHDRFQQITLPRFIRSVHVHSFDFGSVPPEIEIKDICDPLPDFYEDDEDYPDEEGDEAENEAEDATPGAGDKLRDSSNPSNRPSRDSQSRERGRGAEGPVGRSIDHNQLRPSQPPARPSTKRSSLAPNELGSPFFPGALTPGIPGGTSNMNYFHLPLSAGLSGAATPLAAVAGAQLHSWLDNPHRPSTPTNMRLRHAASVNSLTLTPQSHPDPTSRPSSRHQHDEGKRQSFAGSDDGASPHGYTRTPSASPHRMHEKSPEDIQVVTHVQYSGNIKMSLTAEILLDYPMPSFVGIPLKLNITGLTFDGVAILAYIKKRAHFCFLSPDDADALVGSDIGFNGLQTDAQGQNPRPVQRPKIGGLLEHIKVESEIGGQGSGKQVLKNVGKVESFVLEQVRRIFEDEFVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  mdm12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The mdm12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-mdm12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component mdm12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RS9_SHIDS
Sequence: MAENQYYGTGRRKSSTARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YCF12_SYNS3
Sequence: MGFDIHLIANFGALALITLAGPAVIFILFYRRGAL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS14Z_BORBZ
Sequence: MAKKSMIIRALRKPKYKTRQNNRCKLCGRPRGYLRDFCMCRICFRKYASEGLIPGVSKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SYS_SYNWW
Sequence: MLDAKLIKANAALVEQQLEKRGLSGVLKPFLALDEERRKILVQVEERKNFRNNSSQQIGKMKKEGLNPADLMEEVRQAGQQIKELDEELARVEKEIEKILLNIPNLPHESVPVGEDEKSNQEVRRWGEPRQFNFEPQAHWDIGPALDILDFERAAKLSGARFTVYKGAGARLERAVINFYLDIHCGEHGYREILPPFMVIADCMVGTGQLPKFAEDMFKLEGKDMYLIPTAEVPLTNLYREEILEAKDLPFYLTAYTPCFRAEAGSHGRDTRGVIRQHQFNKVELVKLCEPQNSYEELEKLTKDAERVLQLLGLPYRVVVLSTGDMGFSAAKTYDIEVWMPGYQDYREISSCSNCEDFQARRANIRYRPDPKAKLQYVHTLNGSGVAIGRTVAAILENYQQEDGSVIIPEVLRPYMGGLEKINRPEA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_SALPC
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQNQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_YERPY
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RPOY_LEUMM
Sequence: MIYKIYYQEHPERNPKRETTISMYIEAESLPQAREIIEENTEYNVEFIEELSDKAVTYEKANPNFEVTTF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: FBL30_ARATH
Sequence: MAMMRTSPRDSISNLPDEILGKILSLLPTKVAASTSVLSKRWRNLLGLVDNLCFDESMVVYPNEEEETSGSLRFCDFVDKTFALLSNSHIKKFSLSRVYKYNDDVDGMVRRWIRTVMERGLLEIHLHATPMSFVAIETKLLTSNTLVKLTLSARCFVEVERVFFPALKSLSLFSILGDYTNYIRLIDGCPVLEELYMRDGDYPFLRLTCGTNVESASLKRLVIFTHNPNEMIWHELIYFEAPSLVYLDYSSYVSAKYDVVDFDLLVEARLSLRLWVSTNDYDYSDDDDDDDDDDDDDDDGDYYIVEPKAPIFGDVTELLAAIRNITTLHLSPDSLEVFHFCCKSMPVFNNLLNLSIESNKDKGWQVMPLLLKSCPNLHTLVIKGLVHRVTSRCGDACACIPKKQRKIVQKEEALCCLRTCQVKVLQISEYGGYFQELKQMRHFLGKLECLETVKVGVHAENNNNSEFLRANVLTLPRVSAKCNVHFI
What are the official names of this protein?
F-box/LRR-repeat protein At1g48400.
Protein: EXOC4_DICDI
Sequence: MDDNEEKKLDENKISKVLSSIPEQYHKTSFQARRTALDYMRSSNRKELLNQIGDWLDEVNVETDNIVDVYFQGFNKSIHNYSRILEFMGTSHGNALLMSKEVEETNKLINFNGTGIERLWKRNLEYYYMIEILEKMEELKKVPDLLNKYIKGNHFVHAANILVNSISTLNERDLVNVNALMDLRQMLVEKKESFKDMLVEKLNDHIYLKTKSSLKAFEYDDENNLQSNFKKILLSNKNSNSNNSNNTFKSPLPPTTTSPFKPQFTGAFQTKASQEKAEKAAANLYNQERLSQSNQPEVLKLEEISKTSNSKEDLNIDPEQDGKLFMTLLVEALNVLEYLSPAVGLILGRISIELKTAITNSITLITNVYHSEGRVIPKMPGESSNSSNGSNGSNGGGNNSMNGSGGINGNGSTASSSSPTSSTSSNIGANGLSPSVLSKNSHIGSATFSNIDEYSAAFNFLTETFNRNDLLANQTHNIPLVDLLKMIFNKVNMVFKNHLQLSKIFNDAIRKSELKIRANKFDFKEETEGGGGDSDNDFEGTPKPTKLQKSKVEIADVYDASLVWEIIQKEIREMLRVHLQDTSSLLLSTKSRLNPDGTESNSGKSQRLFSFTNSIVTDNWNGSISPMVTTSPTSPNGTSGADAIDSNSGGPAVISIFKASQYNVTPIYPMIVKFTDHLDKTLRDRTGTPTTTKTTTTITTTTTNSYHNQNSKKGLLRLYIDDFVHRNFLQHIKNDYKDRFAHSIESTEAFKPLERYKLVFRLKETKPILNSTLQIFQFVIELFSDIVAMSHYVVEFGAIIQVSLLRYYEKCLSKFSQEIDPTLTNQLLNTDLYKYLLASLAVSSKKQDVAKFQDSREEEYEFKLESDLFNHPEKPVLKNQLILNIEKLTMLANMSHSLNWLADKIVQLLIVQEDQKEKYTQQQQQQQQQQQQVDSIKTPSKLNSGINSGGNSTASNKENNSTTTGSNNFIGTFNQMSAESIEALKTMEEPIKDIAQRFKDLSKRCLLALRIEYRIHCFYFLEGFKRAQYMCEEERTDPDSFIVELNKDLSASEEMMSIYLTSDKCNFLFSGIAKLIGKLLISKLVHVNSINDNGVAKLCKNVFTLQQNLSNIIVKREIFFDRIRQFYQALSAEDELLNYLLEKMSQPFFSLEEGKIIIDFLQRTKRISPNAILTLEAKYKNM
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 4, Exocyst complex component Sec8.
What is the protein family that this protein belongs to?
Belongs to the SEC8 family.
What are the subcellular locations of this protein?
Midbody, Midbody ring. Cell projection.
Protein: EOLA1_MOUSE
Sequence: MKFPCLSFRQPYAGLILNGVKTLETRWRPLLSSVQKYTIAIHIAHKDWEDDEWQEVLMERLGMTWTQIQTLLQAGEKYGRGVIAGLIDIGETFQCPETLTAEEAVELETQAVLTNLQLKYLTQVSNPRWLLEPIPRKGGKDIFQVDIPEHLIPLEKE
What is the function of this protein?
May play a role in cell protection during the inflammatory response.  In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression.
What are the official names of this protein?
Protein EOLA1, Endothelial-overexpressed lipopolysaccharide-associated factor 1, Endothelium and lymphocyte associated ASCH domain 1.
What is the protein family that this protein belongs to?
Belongs to the EOLA family.
Protein: FIEF_SALPA
Sequence: MNQTYGRLVSRAAIAATAMASALLLIKILAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLFLTSIQNLIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILRRFPGSDVIIHQDPCSVVPREGRKFELV
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURE_MYCA1
Sequence: MVSVPTGLRPSAVPGVRLPALADQVGAVMAGPDRRAAVPDVTVTGVTLRAQDVLPGDLFAALPGATTHGARHAAEAIERGAVAVLTDAAGVAQLTGGRTTPTLLHPRPRSVLGELAAAVYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTPEAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLGTGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGRMEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAAELADLVVVTDDNPRGEDPAAIRREILAGATESGCAAEVIEIGDRRAAIRHAVAWAGPGDVVLVAGKGHETGQRTGEHTRPFDDRVELAEALREAVGPRKAQG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y309_MYCGE
Sequence: MKRFLHRVKWPLLLSSIAVSLGIVAVACAQPNSRTIENLFRPSSAFTDKNDGSINATLYKALENREGLTQYLTMRLAPVLRNFYEENVDDDIKRNLRTFNTDTDNSFVNQEQNLRNQYRGDYLVRLQTDILDNTGGNQANWKLRDVNNKIVDDFINKLFTKNFVEYVDKSVGVLSTPLKGLIENQSNWNNIKIQAKFVDKNKRLRINNDAVYAAIQDKLLDQFVTNENPNLVSRVVFTNETPNDGFDNYFNPDLIKSPTPSYQFQVFNKYNQQDNSIKGANGFHILASNLQSYVNTNNKTIDIPNKFSSDSGGKLLLKASDMFDTFDPSFSAAFIQGYLALQKKSKGAEQTEYTKLEKDKSIIENFFVENNSAKAAMKSASSSSQTTTVHKTDLAKIFKENETTKSTDVFKGEYQKKFSNATSTSNSDSSNNSAIVDLKELKKDNNSQPDLILARGKDGIHLMGVDGGGYYLSESGRDVNKQKQFLLFRALQTKYGLIDTNTTYDFKLFDEVKKHFDKNRVLFLFNALFKLVDSKESNFLSFPQFKKFSDSIITVKNELKDLVESQYQQIVFNEVATAENKVALKLAERNQPFIDNERNKQIWMNGLAAVLPYEQDSKTGHYNELGIYYKDIIDKVSSNTSNSNSNSNSSSSDPFSKKIIDKLKENKKKVEAAVKKHVDELKVSVIPSPQYSQIILVDTKLSSDPRNTSLALNLALNAVLSSDELQNTIRRDYFVNDDQFKQAIDLDKLTFKNWNSLNNENWNIFKYTYLFDLFQKQANPSIFGNGVNESSTDNKPKINGVLDSLYNSLNLEERLDSNDLINYYSYLYTVQWLLKDNLKNLKQNLQAKLSRTTNSFLVWSLASDKDRNNTASQAMSVSSSKSVLVKMANNVASQTNQDFTKQEQQNPNYVFGSSAYNWTNNKTPTVNSAANDISSLYYTKNNGSSSTSLTLMQKSAQQTNNQQRRFGFHGIVTNTSSNNLPDAVRNRLFTSFVSQSEKSSSNGGQAQLQSTQSSGSNETIYKGALFSFGSLTKLIETIDNIPTQAEFDALYNHLTSNLNINVTGVDRSKSLQEQKTNLKNFANSNFNNTQTVQLKQAQSKTNNSNFNDVFSRFEGYIGTNKTSNYSSYNFLQDNQIYHAVYAKQINLEDVSMLGSDSLNSTDSNNSKRLDLSLEEFLSTVALEALNPNNQTQAINALIANAKNGLVRVGDNRLFSAISSQWVRKF
What are the official names of this protein?
Uncharacterized lipoprotein MG309.
What is the protein family that this protein belongs to?
Belongs to the MG307/MG309/MG338 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLYA_CLOB1
Sequence: MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMESMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFAAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYEKLKKIALENRPKMIVSGASAYPRIIDFQKIREICDEIDAYMMVDMAHIAGLVATGLHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLYQNA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_NITMU
Sequence: MGLAKRIIPCLDVTNGRVVKGVKFVSLRDAGDPIEIARRYDDQGADELTFLDITASSDDRDLILHIIEEVAAQVFIPLTVGGGVRKVEDVRRLLNAGADKVSINTSAIQNPQLVADAAGRYGSQCIVVAIDAKRAGQGWEVFTHGGRKPTGLDAIEWAKKMQSLGAGEILLTSMDRDGTRDGFDLALTRAVSDAVDVPVIASGGVGNLQHLVDGVVEGHADAVLAASVFHYGEYTVRQAKEYMSQHGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_SYNY3
Sequence: MPELPEVETVCRGLNRLTLEQTIGGGEVLLDRSLAYPVSVEDFQKQITGCRLVGWQRRGKYLLGELRSNQAPGPAGWLGCHLRMTGQLLWTERDQQRPRHTRVVLHFEGGWELRFVDTRTFGKVWLLPGDRPWAEVMTGLGQLGPEPFGADFTAEYLYEKLKSSRRPLKNALLDQRLVAGLGNIYADEVLFFCGFHPTMASNQVSLQDCELIHQQIQATLTAAIEAGGTSFSDYRQVTGINGNYGGMAQVYGREGEPCRHCGTVIAKIKLGGRSAHFCPQCQPKLER
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ACYP_NOSS1
Sequence: MPNSTPQSQLIRAHVFVTGRVQGVGFRYSTVDTASQLGLTGWVRNLPDGRVEAVFEGVRDIVEDMVRWCHAGPPAAVVQDVAVEYEEPEGLRGFEVKRLVK
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL16_STRR6
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL6_STRZP
Sequence: MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIRVEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSKLVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TPIS_LEPBA
Sequence: MRKKIIAGNWKMNLTLAEAKEITKGLLSACDSSSYEIMVFPSALHLESVASIARDSQLIVGAQNAYQSGLTAMTGEISPVQLAELGIQTVLVGHSERRQFLGETSEFDNTKISYFLKHGLRVVYCVGETWAEREKGNTFSVLEDQIGKGLKGITSDLFKNLVIAYEPVWAIGTGKVATPVEAEEAHAFIRKEIGKLFVGADLVAENIQILYGGSVKPDNIKELLAKPNIDGGLVGGASQKLDLFLGLLK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_ANADE
Sequence: MARWRPDTAEREATPEALYLRRREFLALGAAGAVGLLLPRGARAGEPTGAALQVARKVDQAGGETPTPWDSVTGYNNFYELGTSKEDPSRNAGSLRPRPWTVTVAGEVKKPQTLDLDALTRMFPLEERVYRMRCVEAWSMVIPWVGFPLGDLVRRLEPTSRAKYVAFQTLLDRDQLPGQRRPVLPWPYVESLRIDEAAHPLALLAVGLYGRVLPGQNGAPLRLVVPWKYGFKGAKSIVRITFLADRPHTTWNDAAPDEYGFYANVNPEVDHPRWSQARERRIGEFFRRKTLPFNGYAAEVASLYAGLDLRKNY
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.