PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_ECO57
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_METS5
Sequence: MPGNSFGKIFRITTFGESHGPAVGVVVDGVPAGLRLSQEDLEFELSFRRPGRLYVSGRREKDVPEILSGVYNGRTTGSPIAIVVKNTDVISSFYEEVKVKPRPGHADLPFIMRYGYENWDYRGGGRSSARETVGRVAAGAIAKKLLMFHDTWIAGRLKSLGPVDSPPADFLQILCSKYSPVRASDPETEAKFQELVKQATVEGDSYGGVAEIVVKNPPAGLGEPVFDKIKADLAKAILSIPAVTGFEYGLGFQASRMKGSEANDSIVRKGERLGWRENKSGGILGGITTGEDIVVRCSFKPTSSIRKPQGTVDLRTGEPAEISVLGRHDPAVAIRGVSVAESMVALTLVDHSLRSGVIPPVKLEERQAEVIEDRWRRYMEECRPTAESQS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KIF2A_XENLA
Sequence: MVTSLNEDSESITVEWIENGDTKGKEIDLESIFSLNHDLAPDEEIDPGPEMPPPPAPTTKVNKIVKNRRTVAPVKNETPAKDNRVAAVGSARARPIQPIEQSASRQQNGSVSDISPDQPGKKDFGLASRRKSNCVKEVEKLQEKRERRRLQQQELREKKAQDFDATNPNYEIMCMIKDFRGSLDYRPLTTSDPIDEHRICVCVRKRPLNKKETTIKDLDVITIPIKDVVMVHEPKQKVDLTRFLENQTFRFDYAFDETAPNETVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFQMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIEIGNSCRTSGQTSANAHSSRSHAVFQIILRKKGKMHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELDPSRCRRPPPHDTSCPQTSWMTWKQCGEWGVAPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFPGTSIRWLEGLKKCLLEMTEEVDYDADSYATQLEAILEKKIDILTELRDKVKSFRAALQEEEHASKQINPKRPRAL
What is the function of this protein?
Plus end-directed microtubule-dependent motor.  May regulate microtubule dynamics during axonal growth (By similarity).  Required for normal progression through mitosis.  Required for normal congress of chromosomes at the metaphase plate.  Required for normal spindle dynamics during mitosis.  Promotes spindle turnover.  Implicated in formation of bipolar mitotic spindles Has microtubule depolymerization activity.
What are the official names of this protein?
Kinesin-like protein KIF2A, Kinesin-related protein xKIF2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of plk1.
Protein: SYS_SHEON
Sequence: MLDPKFLRNELAVTAERLATRGFILDVAHLTQLEEKRKSLQVATEELQASRNAISKSIGQAKARGEDVDAIMAQVGDLGAQLDAKKVELAAVLEEVNAIAMSMPNLPDESAPIGADETENVEVRRWGSPRSFDFPIKDHIDLGEGLNGLDFKSAVKITGSRFIVMKGQIARLNRALGQFMLDLHTTEHGYTEAYVPLLVNEASLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDSIVDEDELPIKLTAHTACFRSEAGSYGKDTRGLIRQHQFDKVELVQLVKPEDSMAALEVLTGHAETVLQRLGLPYRTVVLCTGDMGFGSSKTYDIEVWLPGQNTYREISSCSNMKDFQARRMQARYRVKADNKPVLLHTLNGSGLAVGRTLVAILENYQNADGSVTVPEALRPYMGGLTQIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAG6_MOUSE
Sequence: MEPSDSASTAMEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTQLPSGASSGTGSASATHGGAPLPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGTQAQASQPPPQTPQTVASETVALNSQTSEPVESEAPPREPMESEEMEERPPTQTPELAPSGPAPAGPAPAGPAPAPETNAPNHPSPAEHVEVLQELQRLQRRLQPFLQRYCEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACAPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGARPPPAPGAEAATPGSAQATSLPPSSTTVDSSTEGAPPPGPAPPPASSHPRVIRISHQSVEPVVMMHMNIQDSGAQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGALQGAGLGTNTSLAQMVSGLVGQLLMQPVLVAQGTPGMAQAQAQAQAQAQAQAQAPAPAPAPAPAPATASASAGTTNTATTAGPAPGGPAQPPPPQPSAADLQFSQLLGNLLGPAGPGAGGPGMASPTITVAMPGVPAFLQGMTDFLQASQTAPPPPPPPPPPPPAPEQQSTPPPGSPSGGTASPGGLGPESLPPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQTLPEEPMEVQGAERTSPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASADAEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAHRAFADDP
What is the function of this protein?
May mediate ricin-induced apoptosis.
What are the official names of this protein?
Large proline-rich protein BAG6, BAG family molecular chaperone regulator 6, BCL2-associated athanogene 6, BAG-6, HLA-B-associated transcript 3, Protein Scythe.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome. Note=Normally localized in cytosol and nucleus, it can also be released extracellularly, in exosomes, by tumor and myeloid dendritic cells.
Protein: ATPA_SYNS3
Sequence: MVSIRPDEISAILKQQIEDYDKSVSVTNVGTVLQVGDGIARVYGLQQVMAGELVEFEDGTEGIALNLEDDNVGIVLMGEGLGIQEGSTVRATGKIASVPVGDAMLGRVVNPLGVAIDGKGDLATTESRLIESPAPGIIQRKSVHEPMQTGITAIDAMIPIGRGQRELIIGDRQTGKTAICIDTILNQADQDVVCVYVAIGQKAASVAQVTEVLRERGALDYTVVVAANASEPAALQYLAPYTGASIAEYFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDAMGKGSMTALPIIETQAGDVSAYIPTNVISITDGQVFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDAATQQQLSRGKRLRELLKQPQFSPLILAEQVAIVYAGVKGLIDDVPVEEVVQFSRELREYLKSNKPEFISKIQTEKVLSPEAETTLKEAIAEVVSTMLASAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ZN175_HUMAN
Sequence: MPADVNLSQKPQVLGPEKQDGSCEASVSFEDVTVDFSREEWQQLDPAQRCLYRDVMLELYSHLFAVGYHIPNPEVIFRMLKEKEPRVEEAEVSHQRCQEREFGLEIPQKEISKKASFQKDMVGEFTRDGSWCSILEELRLDADRTKKDEQNQIQPMSHSAFFNKKTLNTESNCEYKDPGKMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDTEQLDDVVGSGQLFSHSSSDACSKNIHTGETFCKGNQCRKVCGHKQSLKQHQIHTQKKPDGCSECGGSFTQKSHLFAQQRIHSVGNLHECGKCGKAFMPQLKLSVYLTDHTGDIPCICKECGKVFIQRSELLTHQKTHTRKKPYKCHDCGKAFFQMLSLFRHQRTHSREKLYECSECGKGFSQNSTLIIHQKIHTGERQYACSECGKAFTQKSTLSLHQRIHSGQKSYVCIECGQAFIQKAHLIVHQRSHTGEKPYQCHNCGKSFISKSQLDIHHRIHTGEKPYECSDCGKTFTQKSHLNIHQKIHTGERHHVCSECGKAFNQKSILSMHQRIHTGEKPYKCSECGKAFTSKSQFKEHQRIHTGEKPYVCTECGKAFNGRSNFHKHQITHTRERPFVCYKCGKAFVQKSELITHQRTHMGEKPYECLDCGKSFSKKPQLKVHQRIHTGERPYVCSECGKAFNNRSNFNKHQTTHTRDKSYKCSYSVKGFTKQ
What is the function of this protein?
Down-regulates the expression of several chemokine receptors.  Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
What are the official names of this protein?
Zinc finger protein 175, Zinc finger protein OTK18.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL1_POLNS
Sequence: MTKLSKRVKVIQSKIDRNKFYSLDDALNLVKECATAKFDESIDVAVQLGIDAKKSDQVVRGAVVLPAGTGKYVRVAVFAQGEKAEQAKAAGAEIVGMEDLADQIKSGKIDFDVLIASPDTMKIVGTLGQVLGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIVHASIGRRSFEPTALKSNLLALLEALNKAKPPASKGVYLKKVAVSSTMGAGVRVDQASLQAAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: EIF3I_BOVIN
Sequence: MKPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYMRIPCNDSKITSAVWGPLGECIIAGHEGGELNQYSAKSGEVLVNVKEHSRQINDIQLSRDMTMFVTASKDNTAKLFDSTTLEHQKTFRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, eIF-3-beta, eIF3 p36.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_STAAM
Sequence: MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3C_DROYA
Sequence: MSRFFANGSDSESESSEDEIQATNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVAQESDGGDAGDDSDAGVKPTEAAPKAVKSAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKEEKDDDKRKDKRKEQKVKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMLKLLLANTDIIMSESVAEEHEEYVTAPFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYKFDPEVLKKKRNEVPATTSTSVDVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQENVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQQVQTIDEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_COXBU
Sequence: MNEERLFEILLAPHISEKGALTTGQYVFEVMPDATKPEIKRAVEKQFNVTVKSVRTCNVKGKTTRFRQVRGRRKNWKKAYVMLAPGSEIDIAAGE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RNY2_PEDPA
Sequence: MATILIVVLLLASIGVGYGLRAKKHSETLAQARKAAEKIIEHERQKTKAEVAEYEKNSVQETQQYQETIDQELADDLHDNQRKEAWIEQRMNLLNQKKIVLTNRADALAKKRQSLLQERDNVRTTLGEAKQLITDRWNKLQEVADLEEQAASKLVLKETKQDAIRSKDEFVNNAQTELESSCEREAEDLIALAMEHSDVPRGQAENHRSFIAENAEYLGKLIGNSGQNVRAIEALTGVDIVIDDQEKEVILNGYDPVRRAVAMETMEMIKTEKRVVPDTIERLVNKANKVIDQRIRQYGEDAVRELKLKYVAPDLIKFIGRMHYRTSYGQNILEHSIETAKLAGIFAVELGEDATLARRAGLLHDIGKSIDRDIEATHVELGVELTTKYRESPVIVNTIASHHGDVEARYVIANLVEAADAISGARQGARSESVADYIQRIKSLEEIANKHPEVKESYAIQAGRELRVIVQPKETDDKTIHSLATNVKNQIEEDVTYPGQVKVTVVRKLEIVEYVEKKQA
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y 2, RNase Y 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS2_CITK8
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAANSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ADDA_STRS2
Sequence: MDGTNERRSGLMAFEQFLSAEEIKAVQLAEAHSDKQQKRTAEQIEAIYTHGQNVLVSASAGSGKTFVMVQRILDKLKRGIGIDQLFISTFTVKAAGELKERIEKKLNETIAETTDMELRRHLSAQLADLTKADIGTMDSFTQKLVTTYGYSLGISPQFRILQDETEKASLKKEVFDQLFADYLEEDENGAFRKLVRNFSGNRKDNSGFRQVVYQVHDFSQSTSSPTKWLKEQAVQADLYSQERIEQMLEQGFKEKVLDKLYQAADFFRYHVEWGRNDFGSAKYFANVEEVLDLLTGLDSLDQKDLMERVERILLINNQSRGKGLTNANRPKDEHLIAFKEEYNAGKSQIISELRDLGQEVYELTLLKDYQVQALPLLILLRDFVLDFSQAYLDVKIKEAAFEFGDIGHFAIRILEENADIRQFFQEKYHEVMVDEYQDNNHSQERMLDLLSNGHNRFMVGDIKQSIYRFRQADPMIFQEKFELYQANPQSGKLILLKENFRSQIEVLEATNAIFTRLMDRQVGEIKYDDTHSLVAGSPGQKIAQPKNEMEYLIYDQQDSANSSTDAEEETPLTAGEIEVVAKEIIRLHNEEGADFKDITLLVQKRTHNDLIMSIFEKHGIPIVADGGAASYLQSLEVMIMLDTLRVINNPLNDYALVALLKSPMFRFDEDELTRISLQAGTGFFYQKMEIAQQASGQHPELMSEKLKKKITDFLSILENWRAYAKLHSIYDMIWKMFNEKFYYDYVGALPNGSKRQANLYALGLRANQFEKTGYKGLSRFIAMIDRALANDKDLADVQEFLPQNAVQLMTIHKSKGLEFKYVFLMNIDKRFNLEDHYQSVIISRKNGLGIQYLADMKDKVNSPLPQVRVLMNTLPYQNNLQELKIANLSEQMRLLYVALTRAEKKLYLVGKGNADKLAEKYDGKKENGVLAQSTRESMATFQDWILAIDEAFSGEDLHFKKVFVTDEDLTEEKIGKLTLKSKLEDASLKDIRQSEDIAQALDQLSSVQELNERYKAAIELPSLRTPSQIKKLYEPILEQEGMEVMEKYQPKRTFNLPDFSKKPKITGAQVGSAVHELMQRLDLSWLVTEDTVRAALEAVHAEQAIKDKINVQMILDFFDTDLGREILANTDKLHREAPFASLQTDSVSQENFVLRGIIDGYLLYDDHIVLFDYKTDKYDQPIQLSQRYQAQMQLYAEALKKAYKIDRVDCHLILLGGERIEVVEVNI
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: FTSZ1_HALSA
Sequence: MDSIVQDAIDEAEESEDSASEPADVAGGGGDTVPTGTMTDNELEDVLQELQTNITVVGCGGAGSNTVDRMATEGIHGADLVAANTDVQHLVDIEADTKILMGQQKTKGRGAGSLPQVGEEAAIESQGEIRDSIAGSDMVFVTAGLGGGTGTGSAPVVAKAAREQGALTIAIVTTPFTAEGEVRRTNAEAGLERLRDVADTVIVVPNDRLLDSVGKLPVREAFKVSDEVLMRSVKGITELITKPGLVNLDFADVRTVMEKGGVAMIGLGEADSDAKAADSVQSALRSPLLDVDISSANSALVNVTGGPGMSIEEAEGVVEQLYDRIDPDARIIWGTSIDEQIQEEMRTMVVVTGVDSPQIYGRNEAAEGDGPAQESTPEPEPEPQAGSEIEDIDYVE
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ 1.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: PB1F2_I96A3
Sequence: MGQEQGTPWIQSTGHISTQKEEDGQKIPKLEHRNSTQLMGHYQKTMNQVAMPKQIVY
What is the function of this protein?
May play an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm, host cytosol.
Protein: CLPX_BRUSI
Sequence: MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: THUM1_BOVIN
Sequence: MAARIQQSPQPGGGKRKGKAQYVQAKRARRWDGGGPRQLEPGIQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFADKDQQPSGSEGEDDDVEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDIYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLSNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSAKDLSQLNPKQAAQTGNGKEAKLESGDKSSQNDPAEGKNNQQVVPENSEELGPTESISETHVVNEGVAKPELASQVTEGSESNENDL
What is the function of this protein?
Functions as a tRNA-binding adapter to mediate NAT10-dependent tRNA acetylation modifying cytidine to N4-acetylcytidine (ac4C).
What are the official names of this protein?
THUMP domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the THUMPD1 family.
Protein: AROE_PSYA2
Sequence: MTQHFIVIGNPIAHSKSPEIHTLFGAHAGLDICYQCQYCPDDPASFTAVIEAFFHGGGVGANVTVPFKQVAYECCAARGGLSEHAKIAGAVNTLSLNQALLASGVSRAEALYGDNTDGQGLVNHMQRLGWPLNGARIAIIGAGGAARGVVLPLIEAGIEALTIANRTLSKATELVNELSTASVVIHNQQIQTCCTADLSGDFDIIVNATSIGLSGETLPLADELNCQYAYDMMYGRELPFLQHFAARGAQTSDGYGMLIGQAALSFECWTGHAIDVTQATAALEKSSI
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SNAY2_LYCMC
Sequence: MKTLILVVIALMVIEVKSDGYLMVRAGREKGCKIWCVINNEYCDKDCKLKGGNYGYCYFWKLACYCEGLPTSSPDIWTYEKNTCST
What is the function of this protein?
Binds voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin LmNaTx34.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y617_SYNC1
Sequence: MAECLSQTDKGVVLSVHVQPRASRNELAGLQGESLKIRLTSPPVEGAANKLCREFLAKLLGVAKSRVTLVSGDKSRHKRLLIEGVTLDEVRNKLL
What are the official names of this protein?
UPF0235 protein Pcar_0617.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RS11_METS5
Sequence: MSSKREIRWGLARIYASQNNTIITITDITGAEVISKASGGMMVKADREKPSPYAAMLAANKAASDALDKGLMAIHIKVRAPGGAGPKTPGPGAQPAIRSLARSGFIIGRIEDVTPIPHDTIRRPGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TRIA_ACIAI
Sequence: MQTLSIQHGTLVTMDQYRRVLGDSWVHVQDGRIVALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQILLRGGPSHGRQLYDWLFNVLYPGQKAMRPEDVAVAVRLYCAEAVRSGITTINDNADSAIYPGNIEAAMAVYGEVGVRVVYARMFFDRMDGRIQGYVDALKARSPQVELCSIMEETAVAKDRITALSDQYHGTAGGRISVWPAPAITPAVTVEGMRWAQAFARDRAVMWTLHMAESDHDERLHWMSPAEYMECYGLLDERLQVAHCVYFDRKDVRLLHRHNVKVASQVVSNAYLGSGVAPVPEMVERGMAVGIGTDDGNCNDSVNMIGDMKFMAHIHRAVHRDADVLTPEKILEMATIDGARSLGMDHEIGSIETGKRADLILLDLRHPQTTPHHHLAATIVFQAYGNEVDTVLIDGNVVMENRRLSFLPPERELAFLEEAQSRATAILQRANMVANPAWRSL
What is the function of this protein?
Displaces two of the three amino groups from melamine, producing ammeline and ammelide as sequential products (PubMed:11274097).  Can also catalyze deamination of other s-triazines such as CAAT (2-chloro-4,6-diamino-s-triazine) and aminoatrazine (PubMed:11274097, PubMed:12200330).  Has no activity with ammelide, atrazine, halo-triazine substrates or with pyrimidines (PubMed:11274097).
What are the official names of this protein?
Melamine deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
What are the subcellular locations of this protein?
Cytoplasm.