PharMolix/UniProtQA huggingface dataset:
Protein: TGDS_MIMIV
Sequence: MKNILVTGGLGFIGSNFVNHISSKYDNVNIYVYDIGDYCASVENVEWNNRTKLIKGDIRNFDLIMHTLTEHEIDTIVHFAAHSHVDNSFKNSLAFTETNVFGTHVLLECSRMYGKLKLFFHMSTDEVYGEIDTTDTSREVSLLCPTNPYAATKAGAEHIVKSYFLSYKLPIIIARCNNVYGRNQYPEKLIPKFICSLLDGKKLHIQGTGNSRRNFIHAIDVADAVDLVINNGVIGETYNIGVTNEHSVLDVAQILCDIAGVNLENQLEYVPDRLFNDFRYNITNDKIKSLGWEQSRKDFKKELVELFDWYKVNRHRYNIPGSQ
What are the official names of this protein?
Putative dTDP-D-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: RP07_VACCA
Sequence: MVFQLVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNECCRLKLSTQIEPQRNLTVQPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.
Protein: 5051R_ASFK5
Sequence: MFSLQNLCRKTLPDRKLPEFFDDYVLQLLGLYWENHGTIQRAGNNCVLIQQHNLIPVNEALRIAASEENYEIVSLLLAWEGNLYYAIIGALEGNRHNLIRKYDDQIKDHHEILPFIDDPVIFHKCHMMRRCFFNCILYQAVKYSKFSVLLYFKYILKENLPLVHSLIEKACEDHNYEVIKWIYENLHIYEIMDTFKCAIAHKDLHLYSLGYTFIYNRIVPYKYHHLDIRILSRLQLLHKVTAKGYLDFILETLKYDHNKDNINIILTQAATYNHRNILTYFIPQSTYAQIEQCLFVAIKTNASKKTLNLLLSHLNLSIKLVKKLSQYVVAYKSTNIISILSMQQKKKIYLDIILTKVVKNAIFIKFVIGCMVTFSINPERIVKMAARIKKMKLVKNISEHVWKNHAAKLKHLKHAVHTMKHQEGKNRLMNFIYDHCYYHMQGEEIFSLARFYAIHHAPKLFDVFYDCCILDTIRFKSLLLDCSYIIAKNAHDASINIVNKYIGNLFAMGVLSKKEILQDYPSIYSKDYML
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: SDHL_ECOLI
Sequence: MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGRHEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQDAANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQACIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD
What is the function of this protein?
Deaminates also threonine, particularly when it is present in high concentration.
What are the official names of this protein?
L-serine dehydratase 1, SDH 1, L-serine deaminase 1, L-SD1.
What is the protein family that this protein belongs to?
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Protein: RL1_YERE8
Sequence: MAKLTKRMRVIRDKVDVTKQYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFAQGANAEAAKEAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDSEKLKENLESLVVALKRAKPATAKGVYIKKISLSTTMGAGVAIDQSGLSAVVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RNY_FUSNN
Sequence: MALIFAVFFKKIVIDRQIEKLNDLEDEVEKAKLKAKEIVEEAERDAVSKAKEIELKAKEKAYQIKEEIEKEARNSKNEIAQKEARIIKKEEILDGKIEKIEIKSLELEKINDELEEKRKEIDDLRVKQEEELSRVSELTKADAREILLRKVREEMTHDMAITIREFENKLDEEKEKISQKILSTAIGKAAADYVADATVSVINLPNDEMKGRIIGREGRNIRTIEALTGVDVIIDDTPEAVVLSCFDGVKREVARLTIEKLITDGRIHPGKIEEIVNKCKKDIEKEIVAAGEEALIELSIPTMHPEIIKTLGRLKYRTSYGQNVLTHSIEVAKIASTMAAEIGANVELAKRGGLLHDIGKVLVNEIETSHAIVGGEFIKKFGEKQDVINAVMAHHNEVEFETVEAILVQAADAVSASRPGARRETLTAYIKRLENLEEIANSFEGVESSYAIQAGRELRIVINPDKVSDDEATLMSREVAKKIEDTMQYPGQIKVTILRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
Protein: ARI1_XENLA
Sequence: MDSDEGYNYEFDDEEECSEESGADEHEDELELGEVELVEAGLSGSERAGLCGEGGGSALGPGPGGEEDEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFSECHVINPSKKSRTRQMNTRSSALDMPCQICYLNYPNSYFTGLECGHKFCMQCWGEYLTTKIIEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVHCKCGRQFCFNCGENWHDPVKCKWLRKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRSTLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLLHVHEGYEKDLWEYIED
What is the function of this protein?
E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 ube2l3.  Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets.  The initial ubiquitin is then elongated.  E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes.
What are the official names of this protein?
E3 ubiquitin-protein ligase arih1, Protein ariadne-1 homolog, ARI-1, RING-type E3 ubiquitin transferase arih1.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SIM33_MOUSE
Sequence: MHQDDYYPQPSLLVNGSLDQEPQRQLPDMPPRGGDGLPLLAAIIAAFVLLAICIVLAVHFGPALHQGQATLLTEPPALKPENGVYLIHWRLLSLQDSHRESQQGLFIPHSGPALDGHRPSIDEVTYL
What are the official names of this protein?
Small integral membrane protein 33.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DEOD_BACLD
Sequence: MSVHIGAEKGQIAETVLLPGDPLRAKYIADTYLENVECYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIRSYDVKNLIRVGSCGAIRKDVNVRDVILAMTSSTDSQINRVAFGSIDFAPCADFGLLKAAYDAASERNIPVTAGNVFTADQFYNDDSQIEKLAKHGVLAVEMETTALYTLAAKFGRKALSILTVSDHVITGEETTAEERQTTFNDMILLALDTAL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: RS20_ACIBC
Sequence: MANSAQAKKRARQNVKARKHNASLRSMVRTYIKRTLSAIAGGDYAVATEAYKKAVPVIDRMADKGIIHKNKAARHKSRLNAQVKALAN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RIMP_STRPM
Sequence: MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYELVDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSSPGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHKIVNIPYQAVAKVRMAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRX3_ORYSJ
Sequence: MGETAEGVEAGEKYVSIPQLAGVGTLLSNGGKEIPLSSIEGKRICLFFSAHWCRPCRNFTPKLLQIYRKLRNTCKNMEIIFISLDRDEISFLDYFKGMPWLALPFDTGLRQKLCVQFDIEHIPALIPLSTTLSHGFRVEEDAVKLVEEYGVDAYPFGAKRRSELEGMDDARRQGGNLLQLLGCKEREYVISADGIKTPISDLNGKTIGLYFGAHWCPPCRAFTKQLREAYDELKALRPGNFQVIFISMDRNEEEFQASLSAMPWFAIPYSDTTVQELSRIFTIKGIPTLLILGPDGKVFKTDGRRIISKYGAMAFPFTESRAYELEEVLKKERDSLPHRVRDHRHEHELELDMAKAYLSTQLFHQTPSVQPCRLNLKTLREEYHLIFTNSNRKTSRPQSSYTRQQRDLNNLYSDPKHLPQLHKHFDQSNVATAENSLRFLNGEPENSDISSIHVAFADLAGKIRGEDDKRD
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
What are the official names of this protein?
Probable nucleoredoxin 3, OsNrx3.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
Protein: MURI_STRPS
Sequence: MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGPRPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASAAIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSVTKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLLNYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: DRD5_MACMU
Sequence: SILISFPVQLNWHRDQAGSWGGLDLTNNLANWTPWEEDVWEPDVRAENCDSSLNRTYAISSSLVSFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFIL
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
D(1B) dopamine receptor, D(5) dopamine receptor, Dopamine D5 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METK_ALTMD
Sequence: MATHLFTSESVSEGHPDKIADQISDAVLDAILEQDPRARVACETYVKTGMVLVGGEVTTSAWVDIEELTRNTVKEIGYTHSDMGFDADSCAVLNAIGKQSPDINQGVDRASLEEQGAGDQGLMFGYASDETDVLMPAPITYSHRLVQKQAEVRKSGKLDWLRPDAKSQITFKYENDKPVGIDAVVLSTQHCDSVSTETVREAVMEEIIKPVLPSEWIDGNTRFHINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAKRCEIQVSYAIGVAEPTSISIDTFGTGVVDEKTLVALVREHFDLRPYGLIQMLDLERPIYRPTAAYGHFGRDEFPWEATDKAQALKASL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOXA_DICDI
Sequence: MRLPTKEEIQRYWVNEGNKLILVILYTLGNIAAFVYTFVHYYNSPAFEVVGYGVCFARGCAQLLKLNCALILVPVLRNLLSFLRGTFLNNYVPFDKNIVFHKLIAWVICFATFGHVMAHFNNFRLYQDITPQEYKRILGIDYPNLTPIKYAFATLAGWTGHVVCIVMVLMYTSAVESIRRPMFEGFWYTHHLFVVFFGLLVVHGLHSILEPTSFWKWVIGPCALYIVERLIRLLRSKKTTMLIQARIHPSRVIEVRMKTERFKYKPGQYLFLNCPTIAQNEWHPFTITSAPEEDFVSCHINVVGNWTGKLSTLLNPDKKMGIVQENVLKSPDGKPILRIDGPFGAASEEVFKYKQVILVGAGIGVTPFASILKHIKYQMARTYNTTPLIDKVHFYWICRDRNSFEWFSGLIGELEMENHNNFLEIHPYLTGALSAQEIRDVMYGDEEKDLITGFTTPTQFGRPKWDEIFADHALRYAEKDVGVFFCGPKLLSKSLYKASTHYTKTTTCRFHYNKENF
What is the function of this protein?
Critical component of the membrane-bound oxidase that generates superoxide.  It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior (By similarity).
What are the official names of this protein?
Superoxide-generating NADPH oxidase heavy chain subunit A, NADPH oxidase A, Superoxide-generating NADPH oxidase flavocytochrome A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL16_LACLS
Sequence: MLVPKRVKHRREFRGKMRGYAKGGDTVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRNGQVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGVVMFELGGVDEATAREALRLASHKLPVKTKFVKRGEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: OAT_DICDI
Sequence: MDPISSQIQECTSKELIEMESEFAAHTYHPIPVVFKKASGVHVWDVEEKQYFDFLSAYSAVNQGHSHPKIVSALITQAQKCALSSRAFYNEVFPQYAKYITEYFGYEMVLPMNTGAEAVETSIKLARRWGYVKKGIAEDQAIVISCKGCFHGRTIGVISMSDDPSSYNKYGPLMNGIIKIDYNSTQQLEEVLSQHADRVCGFIVEPIQGEAGVVVPDEGYLKKCYELCKKYNVLLVADEIQTGLCRTGRMLCSDWDGIKPDLVLLGKAISGGLLPISAVLGGKDVMLTIKPGEHGSTYGGSPLASAVAMAALDVLRDENLAENAQKLGEHFRAQISNINHPAIQLVRGKGLLNAIVIDPNFTVSAWDICIKFAENGLLAKPTHDNIIRLAPPLTITLEQIDQCVSIIKKVFDSFKN
What are the official names of this protein?
Probable ornithine aminotransferase, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC2_CUPMC
Sequence: MKLEKDRDVLSLKGVSVRYVDSTVALHPTSLDVKQGEFLVLLGASGAGKSTLLRSINGLVLPTKGEVSIPGLAGGVVNAKTLREHRKRCGMVFQQHHLIGRQSVLRNVLMGKLGDRGAFASLWPWSKKDKLEALTVIERVGLLEKALSRADALSGGQQQRVGIARALIQKPRILLADEPVASLDPATAHSVLTLLHEICKKDHLTAIVSLHQVELARSFADRIIGLRQGAVVFEGRAEQLSPDVARNLYAKQSNASNTSASTDSPRTLQSSQTKELLPC
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VATB_METB6
Sequence: MKEYRTITKIAGPLVFVEKTEPIGYQELVNIVLSDGTIKRGQVLDTSDDLVVVQIFETTTGIGRDSGVRFTGETIKMPVGREMLGRILSGGGKPIDGGPEIVPEKRLDITGAAINPWARNSPSDFIQTGISTIDGTNTLVRGQKLPIFSGAGLPHNNVALQIARQAKVPGSTESFAVVFAAMGITKEEANYFMQDFERTGALEHAVVFLNLADDPAVERIITPRLALTTAEYLAFELGMHVLVILTDMTNYCEALRQIGAAREEVPGRRGYPGYMYTDLACIYERAGIIKGQKGSVTQIPILTMPGDDITHPIPDLTGYITEGQIVVNRELHRKGIYPPINVLPSLSRLMNLGIGKGHTREDHKKVSDQMYAGYAEGNDLRGLVAIVGKDALSERDRGLLEFADLFEDKFVRQGYDEDRTIEDTLDLGWDLLSTLPVEQLTRIDRDLINKYHPKLKAGAKKE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: DAPA_DEHMB
Sequence: MKELGRLITAMVTPFKKDGTVDYAQAQKLALGLLDSGSDGLVVVGTTGESPTVTWEEEHALFAAVKSAVGNRGKVIAGTGANSTQEALENTLKAEKIGVDACLLVVPYYNKPTQEGLYLHFKTIAEATKLPCILYNVPSRTITHMNPETVIRLSQIPNIVGIKEASGKLDDIAQIINNVRPDFTVWSGNDSDTLPMLAMGSYGVISVASHLVGNQIKDMITSFVSGNTEHAAAIHRHLTPLIRSLFVVSNPIPIKYALNYLGVEVGGLRLPMTEADEKTAALIRESLKGYTIDLPIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_STREM
Sequence: MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNPASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPHHINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFRDYGIELEGKNAVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLAAICRRADILIVAIGQGHFITKDFVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQAALRRVSQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EFTU_SYNP2
Sequence: MARAKFERNKDHANIGTVGHVDHGKTTLTAAITMALAAQGGGKAKSYEDIDAAPEEKARGITINTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLAKQVGVPSLVVFLNKEDQVDDEELLELVELEVRELLSEYDFPGDDIPITTGSALKAVEALVANPNIKRGEDKWVDKILALMDSVDEYMPLPERDVDKPFLMAVEDVFSITGRGTVATGRIERGRVKVGETIEIVGIRDTRSTTVTGVEMFQKTLDEGMAGDNVGVLLRGVQKDDIERGMVLAKPGSITPHTNFEAEVYVLTKEEGGRHTPFFPNYRPQFYVRTTDVTGTISAFTADDGSSAEMVMPGDRIKMTVELINPIAIEQGMRFAIREGGRTIGAGTVSKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_UREP2
Sequence: MIKSIWIAGGCFWGIQKYFDSIIGVNHTVVGYSQGNVINPSYEQVCTQTTNHTETVQIDYDDRFVSLISILEHLYQIIDPFSLNKQGDDVGSQYRSGIYYVDHDDEFIIKDFLLKKQNQTPKKIMIEVERLRNFNIAEEYHQKYLDKNPNSYCHVDLSLSKKEFR
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: NFAT5_HUMAN
Sequence: MPSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPPAVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSEKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYVLSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGRNTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGKNFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIEKIDLLVSLQNQGNNLTGSF
What is the function of this protein?
Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes.  Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3' (PubMed:10377394).  Mediates the transcriptional response to hypertonicity (PubMed:10051678).  Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17 (PubMed:22266867).  Also involved in the DNA damage response by preventing formation of R-loops; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA (PubMed:34049076).
What are the official names of this protein?
Nuclear factor of activated T-cells 5, NF-AT5, T-cell transcription factor NFAT5, Tonicity-responsive enhancer-binding protein, TonE-binding protein, TonEBP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear distribution increases under hypertonic conditions.
Protein: HDA10_DANRE
Sequence: MASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSETNPKRPRLDATNGGPKESSEPASESNPKKTAQDIVWPEPLKRMPASVRTVVVPPPGVELTLPKNCQHSGDISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLSLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVGETAAKTGLMTVWGHMTCLIQGLARGRTLTLLQGYDKDLLELTVSALSGASISPLGPLRALKPEDVEMMEKQRQRLQERWGLLRCTVSES
What is the function of this protein?
Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine (PubMed:28516954).  Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine (PubMed:28516954).  Has a very weak lysine deacetylase, if any (PubMed:28516954).
What are the official names of this protein?
Polyamine deacetylase HDAC10, Histone deacetylase 10.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Excluded from the nucleoli.
Protein: ISPE_SYNFM
Sequence: MRGIRKGHALALRVGTPAKINLWLEIVRKREDGYHDLSSLMLPVAVYDHVEVAWSHEGGVRLSCDSAEVPDDRGNLAWRAADAYLEAAGVTRGVSIRLEKNIPVGAGMGGGSSDAAAVLLALNRLSENPLSEAVLHRLAVGLGADVPFFLHCVPALATGIGERLLPVHGIPDYPLLLVKPPISVSTGWVYGSLKLTRGESRIKLRSFLDRPWHLSEVLRNDLETVTLNEYPQLGQIKCWLMENGAVGSLMSGSGPTVFGVFAEQRLADGAGELARRVWKDCRVDVTRVLGTPVSARS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MT1_PEA
Sequence: MSGCGCGSSCNCGDSCKCNKRSSGLSYSEMETTETVILGVGPAKIQFEGAEMSAASEDGGCKCGDNCTCDPCNCK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: RL44_CRYNB
Sequence: MVNIPKTRRTYCKGKACRKHTPHKVTQYKKGKDSLSAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKTKHQLALKRCKHFELGGDKKQRGAAISF
What are the official names of this protein?
60S ribosomal protein L44, 60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.