PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_LACJO
Sequence: MTKYIFVTGGVVSSLGKGISASSLGRLLKNRGLKVTMQKFDPYINIDPGTMNPYQHGEVYVTDDGTEADLDLGHYERIVDVRTSKYSNVTTGKIYQEVLDKERRGDYHGATVQVIPHITDMIKKKIMRAALTTDSDVIISEIGGTVGDIESTPFMEAIRQMRREVGEENVMYIHCTLVPYLHAAHEMKTKPTQHSVAELRSIGIQPNMLVLRAEKPIAQELKNKISTFTDVPVDRIIESIDAPSLFDLPLAFQAQGMDQKVCDFLHLESPKPEADMEAWKKLDERAKNLKNETTITLVGKYVELEDAYISVTDALQHAGYLYDTKIKVNKVQAEDITEDNIAEIMKDSDGLIVPGGFGTRGLEGMITSIKYAREHDIPFLGICLGMQMASVEFARNVLGLKDANSAEANPDTKNNIIDIMADKRDEENIGGTLRLGLYPATLKKGTKTREAYDDQDVIQERHRHRYEFNNEYREAFEKAGMVFSGVSPDNHLVEIIEIPNKKFFIAAQYHPEFLSRPQRPEGLFKAFIGAASGLPAQHFN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: KCNJ5_PIG
Sequence: MAGDSRNAMNQDMEIGVTPRDPKKIPKQARDYIPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIVLLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNHAVISLRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQLNQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLPGGCAGAELEAEAEQEGEDEPEGLRGSRETRDSV
What is the function of this protein?
This potassium channel is controlled by G proteins.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by external barium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 4, GIRK-4, Cardiac inward rectifier, CIR, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, KATP-1, Potassium channel, inwardly rectifying subfamily J member 5.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: MURQ_GRAFK
Sequence: MNKKSPDTEKVSNYDYLEKMNTFELLSNINKEDHTIAENVKKQIPSIEKLVDEIIPRIDSGGRLFYIGAGTSGRLGVLDASECPPTFGVSPGIVIGLIAGGDTALRNAVENAEDDTNQAWKDLQEYDISEKDVLVGIAASGTTPYVIGGIKDARNNGIITGCITCSSGSPLAEASEYPIEVVTGPEFVTGSTRMKAGTAQKLVLNMISTSVMIKLGRVKGNKMVDMQLSNDKLVGRGIRMIMEDLNIEKEQAEKLLLEHKSVRKVLDAHKNERN
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: THIE_CHLP8
Sequence: MTIPRRLLCVITDQQSNPVELARMALEGGARMVQLRRKSASGRDLFEWAVRIQALCREYEALFIVNDRVDIALAAHADGVHLGQQDIPVASARALLGPETLIGVSVSTPSEAAKAAEEGADYLGVGHIFPTSSKEKPMPPIGTSAIRPIIEASGLPVIAIGGIELQNVAEVIKAGASGVAVISAVSGSADPVAATRELVKRIRQ
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: CESA3_ORYSJ
Sequence: MEASAGLVAGSHNRNELVVIRRDGDPGPKPLRQQNGQVCQICGDDVGLNPDGEPFVACNECAFPVCRDCYEYERREGTQNCPQCKTRFKRLRGCARVPGDEEEDGVDDLENEFNWRDRNDSQYVAESMLHAHMSYGRGGVDVNGVPQPFQPNPNVPLLTDGQMVDDIPPEQHALVPSFMGGGGKRIHPLPYADPNLPVQPRSMDPSKDLAAYGYGSVAWKERMESWKQKQERLHQMRNDGGGKDWDGDGDDGDLPLMDEARQPLSRKVPIPSSQINPYRMVIIIRLVVLGFFFHYRVMHPVPDAFALWLISVICEIWFAMSWILDQFPKWFPIERETYLDRLTLRFDKEGQTSQLAPIDFFVSTVDPLKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLTFEALSETSEFAKKWVPFCKKYSIEPRAPEWYFQQKIDYLKDKVAPYFVRERRAMKREYEEFKVRINALVAKAQKVPEEGWTMQDGTPWPGNNVRDHPGMIQVFLGQSGGHDIEGNELPRLVYVSREKRPGYNHHKKAGAMNALVRVSAVLTNAPYMLNLDCDHYINNSKAIKEAMCFMMDPLVGKKVCYVQFPQRFDGIDRHDRYANRNVVFFDINMKGLDGIQGPIYVGTGCVFRRQALYGYDAPKTKKPPSRTCNCWPKWCICCCCFGDRKSKKKTTKPKTEKKKRSFFKRAENQSPAYALGEIEEGAPGAENEKAGIVNQQKLEKKFGQSSVFVASTLLENGGTLKSASPASLLKEAIHVISCGYEDKTDWGKEIGWIYGSVTEDILTGFKMHCHGWRSIYCIPKLPAFKGSAPLNLSDRLHQVLRWALGSVEIFFSNHCPLWYGYGGGLKCLERFSYINSIVYPFTSIPLLAYCTLPAICLLTGKFITPELTNVASLWFMSLFICIFATGILEMRWSGVGIDDWWRNEQFWVIGGVSSHLFALFQGLLKVIAGIDTSFTVTSKGGDDEEFSELYTFKWTTLLIPPTTLLLLNFIGVVAGVSNAINNGYESWGPLFGKLFFAFWVIVHLYPFLKGLVGRQNRTPTIVIVWSILLASIFSLLWVRIDPFLAKNDGPLLEECGLDCN
What is the function of this protein?
Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.
What are the official names of this protein?
Probable cellulose synthase A catalytic subunit 3 [UDP-forming], OsCesA3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPB_AJEDR
Sequence: MAGEKGGSRDEEREPLTRGSIEFRDSINSFDYSSSTASLSLAVIDRINGSTQDSRLGEKDQRDDDHDQYRNEEEYDVEDADYIPSGGKTVQKTTKIVLWALLFLCVGGWSLAFVIFLFRGHDTPQTSIASEENISSGGARGNRITLDEVLGGEWAPRAHSISWFPGPNGEDGLILEKDNLSATAYLRVEDIVGRKDPKASKKSIVLMQKKMFTVGRETVYSAQAWPSPDLKTVLVLSDQQKNWRHSFTGKYWLFDVETQTGQPLDPGAPDRRIQLASWSPQSDAVVFTRDNNMFLRKLTSNEVATITTDGGVDLFYGVPDWVYEEEVFSGNSATWWASDGDYIAFLRTNESSVPDYPIQYFASRPSGENPKPGEENYPEVREVKYPKAGAPNPIVDLQFYDVGKGEVFSVDVTSEFADDDRLIIEVLWASNGKALVRETNRESDILSIAIIDVLSRTGRIVRREDVNALDGGWVEPTQSTRFIPADPDHGRLDDGYIDTVIYEGRDQLAYFTPLDNPKPIMLTKGHSEVVNAPSGVDLKRGLVYFVVAGNEPWERHIYSVNFDGTSLQPLTNVTESSYYDVSFSNGAGYALLNYRGPKVPWQKVINTPANENSFEAIIEQNDHLSRKLRLFSLESKVYQHVTVDGFSLPVMERRPPNFDPAKKYPVLFHLYGGPGSQTVSKKFSVDFQSYVASTLGYIVVTVDGRGTGHIGRKARCIIRGNLGHYEARDQIETAKKWAAKPYVDESRMAIWGWSYGGFMTLKTLEQDGGRTFQYGMAVAPVTDWRYYDSIYTERYMRTPQHNQGGYDTSAISNTTALASNIRFLLMHGTADDNVHIQNSLTLLDKLDLDDVDNYDVHVFPDSDHSIYFHNAHKMVYNRLGDWLINAFNGEWLKVHKPTPNNSLFRRAETWGGLPV
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: VG11_SHV21
Sequence: METPKHIRGVWRRDSVLKHREKKFNYSFWNCSVHEHFISITNNREIHILPDDLLLPRCPSIRAILFKQIPSFKFSGSRSGPPGTVTSLYVYGHSKNLIKIKPMVVSECEQELIFKITFALECTIPPGSMEIFILPITFLKLDGLYLLCLEDYTSRIMSTSCMQMGTYLASETPQVFLKGGPVLNKHEPMPYLMAQKTKPFDKKMARVHTVQNEVCEVNSIYRGENHVKVAIQKDSEDINFLDTVVVGLTMTNRALVAFEYNPYFSCPWDWKRQSIPIIYDGPCIRIPAGRLAPVKYNNTYSSIYPNATAIITNSDSCADFHISDCEWKPGKTACIVVTNTSTISVTISSGTHLGEAVFILAPKFFCRKIMSKTHVQKLSSAICLPGNVTINSNKVPKLADLSTYK
What are the official names of this protein?
Uncharacterized gene 11 protein.
Protein: PYRK_LISIN
Sequence: MLQTEMKVIQQTEIADKVYELILSGECVADMSPGQFLMLKPSRSDLLMRRPISICSYDKTAKTCILLYRVEGDGTKDFSSLSKGDSIDVLGPLGKGFDLNTIPAPKTALLIGGGIGVPPMYQLGKELADKGVQVTFVNGFQSEKDSFYEKEMTEYGTVHIATVDGSYGTQGFVTDITKNFPEEPDVIYSCGPKAMLQAVKASFPETKTYLSLEERMACGIGACYACVCPKAGDTKKQFKVCEDGPVFRADEVSL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: RL22_TRIEI
Sequence: MPIDTNTEVKAIARYIRMSPFKVRRVLDQIRGISYREALIILEFMPYRSCVPIRKVLCSAVANAENNKGIDPDTLVISKAFADQGPCLPRYRPRAQGRAYKIRKPTCHITVAVASLVDD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: KRBA1_HUMAN
Sequence: MRENYETLVSVGTAELLPLSAFLSPSEPGRAVGGGSHADEGQEPAGCGDPQGGQPRHSLHLTALVQLVKEIPEFLFGEVKGAMDSPESESRGASLDGERASPEAAAAREPCPLRGLLSCLPDGPTSQPHLATTPTDSSCSSGPTGDGVQGSPLPIKTADKPWPTRKEGPGALGGEPSPPTHSPSRRKSHRGQERGTSEAGISPGNSPLQGLINCLKEILVPGPRHPETSPSFLPPLPSLGTSRLTRADLGPGSPPWAVKTEAVSGDCPLQGLLHCLKELPEAQDRHPSPSGVGNRRLQENPGAWKRGSGGPGYLLTPPPHPDLGAGGLLSVKMENSWVQSPPGPASCQPGRQPLSPSATGDTRGVPQPSWGPEAQAASASSSPLEALEACLKGIPPNGSSPSQLPPTSCSQNPQPGDSRSQKPELQPHRSHSEEATREPVLPLGLQSCVRDGPSRPLAPRGTPTSFSSSSSTDWDLDFGSPVGNQGQHPGKGSPPGSSPLQGLENCLKEIPVPVLRPAWPCSSAADRGPRRAEPRNWTADKEGLRAEACESARLGQGRGEAPTRSLHLVSPQVFTSSCVPACHQRGFKDPGATRPGVWRWLPEGSAPKPSPLHCLESALRGILPVRPLRFACVGGPSPSPSPGSSSSFSGSEGEDPRPEPDLWKPLPQERDRLPSCKPPVPLSPCPGGTPAGSSGGSPGEDPRRTEPRYCSGLGAGTAQDPCPVSQLEKRPRVSEASRGLELGHGRPRVAAKTHERLLPQGPPELPSESPPPELPPPEAAPPVLPASSLQPPCHCGKPLQQELHSLGAALAEKLDRLATALAGLAQEVATMRTQVNRLGRRPQGPGPMGQASWMWTLPRGPRWAHGPGHRHLPYWRQKGPTRPKPKILRGQGESCRAGDLQGLSRGTARRARPLPPDAPPAEPPGLHCSSSQQLLSSTPSCHAAPPAHPLLAHTGGHQSPLPPLVPAALPLQGASPPAASADADVPTSGVAPDGIPERPKEPSSLLGGVQRALQEELWGGEHRDPRWGAH
What are the official names of this protein?
Protein KRBA1.
Protein: Y02C_BPT4
Sequence: MKSKIIAALLLILMIIISIYYSVTVPLMIPTIILGWSLLLLQVKYECIN
What are the official names of this protein?
Uncharacterized 5.6 kDa protein in Gp42-imm intergenic region.
Protein: TGT_BACSU
Sequence: MAEQPIRYEFIKECKQTGARLGKVHTPHGSFETPVFMPVGTLATVKTMSPEELKAMDAGIILSNTYHLWLRPGQDIVKEAGGLHKFMNWDRAILTDSGGFQVFSLSKFRNIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEYDYMKRSVERTSRWAERCLNAHNRQDEQGLFGIVQGGEYEDLRTQSAKDLISLDFPGYAIGGLSVGEPKDVMNRVLEFTTPLLPKDKPRYLMGVGSPDALIDGAIRGVDMFDCVLPTRIARNGTVFTAEGRLNMKNAKFERDFRPIDEECDCYTCKNYTRAYIRHLIRCNETFGLRLTTYHNLHFLLHLMEQVRQAIREDRLGDFREEFFERYGYNKPNAKSF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: SPEH_PSEA8
Sequence: MAIQPLRLDPITVLGKQLVIELFDCVDQRFDDIQWIEESMLEAARQANATIITSAFHKFSPIGISGVVVIAESHLAIHTWPEYGYAAVDVFTCGDVLDGAQAVRVLSERLGSRRHLISSMDRGLGGHRLGLLSRSLAGNGPVDEDSPTLRWALGQGTGVA
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: UXUA_STRU0
Sequence: MEMSFRWYGEDDPVTLENIRQIPTMKGIVTAIYDVPVGEVWPRERIQQLKETVEASGLKISVIESVPVHEDIKLGRPTRDVLIDNYIQTIKNLAAEGIDTICYNFMPVFDWTRTDLAYEYPDGSTALIFDEEVSKKMDPVNGELSLPGWDSSYTKEEMRAIMDAYADVDEEKLWEHLEYFIKRIIPEAEAVGVKMAIHPDDPPYSIFGLPRIITGLDSVERFVNLYDSKSNGITLCVGSYASDPKNDVLEISRRAFELNRVNFVHARNIKLGEGKSFKESAHPSEYGSIDMYEVIKLCHEFGFEGAIRPDHGRMIWGETGRPGYGLYDRALGATYLSGLYEAVVKAAK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: YQGF_STRMU
Sequence: MRIIGLDVGSKTVGVAVSDPLGFTAQGLEIIPINEAKGEFGFDRLADLVKDYKVEKFVVGLPKNMNNTSGPRVEASQAYGKKIKELFDLPVEYQDERLTTVQAERMLVEQADVSRGKRKKVIDKLAAQLILQNYLDRMF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_METCA
Sequence: MKNSMYLPFPSKGLYAITPDRLQGDALLAAAESAILGGAAVVQYRPKSGPASDRLSDGIRLQELCRTAGIPLIVNDSPRLAAEIGADGVHLGKNDGSVAAARHVLGDRAIVGISCYDSLERALRAEAEGANYVAFGALFPSATKPCASRARLETLREAGTRLQIPIAAIGGIDTTNAGQVIGAGADLVAAVEAVFGAADVARAARELCSLFHAPRKRRPRCDDA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RSMH_PELUB
Sequence: MIATIIPDVRNHYPVLLSEIISIITPQYGGTFIDCTFGQGGYTKRILNFPETKVIALDRDSESSIKAQELQNSFEDRLLFKNIKFSQLNNLKLKHENIKAVIFDLGYSLNQIKDPKKGLSFDSIGELNMKMGINEFSAKEAINQLDEKELTKIFKYFGDEADSKRIAHNIVEDRSKREITTEELVRIIESSKRKRNYKTHSATKIFQALRIFVNKEISELIYGLINAAKVVKKDGVIAVVTFHSLEDKIVKYFFKSLSENKSISRHMPKTEEKLNLFKSVIKKPIVPSDKEIRENPPSRSAKLRYVIKKEDFFDFETDILDKFKHLIDIENLSKKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBU_PONAB
Sequence: MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEEKFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAVRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCLAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNELLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEPKRMPCAEDYLSVVLNQLCVLHEKTPVSERVTKCCTESLVNRRPCFSALEVDETYVPKEFNADTFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKTVMEDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
What is the function of this protein?
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.  Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).  The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity).  The rank order of affinity is zinc > calcium > magnesium (By similarity).  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E. coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E. coli (By similarity).  Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
What are the official names of this protein?
Albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_BORBZ
Sequence: MKNIKPLADRVLIKIKEAESKTISGLYIPENAKEKTNIGTVIAVGSNKEEITVKVGDTVLYEKYAGAAVKIENKEHLILKAKEIVAIIEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPS_MOUSE
Sequence: MSAAGDLRRRARLSRLVSFSASHRLHSPSLSDEENLRVFGKCNNPNGHGHNYKVVVTVHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADAVSTTENVAVYIWESLQKLLPVGALYKVKVFETDNNIVVYKGE
What is the function of this protein?
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases.  Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
What are the official names of this protein?
6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase, PTPS.
What is the protein family that this protein belongs to?
Belongs to the PTPS family.
Protein: RL4_CITK8
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: EFTU_CHLPD
Sequence: MAKESYKRDKPHVNIGTIGHVDHGKTTLTAAITSVLAKQGLAQQRDFGSIDKAPEERERGITISTAHVEYQTKKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVYLNKVDIADPELIELVELELRELLTEYNFPGDDIPIIKGSALKALDGDLEGEKSIMELMDAVDEFIPEPLRDIDKPFLMPVEDVFSISGRGTVGTGRIERGRIKINEEVEIVGIKPTRKSVVTGIEMFQKLLDEGQAGDNAGLLLRGVDKTELERGMVIAKPGTIKPHTKFKAEVYILRKEEGGRHTPFFNGYRPQFYFRTTDVTGSVTLPEGVEMVMPGDNLSVDVELIVPIAMDENLRFAIREGGRTVGAGSVTKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZCH10_MOUSE
Sequence: MATPMHRLIARRKAEANKQHVRCQKCLEFGHWTYECKGKRKYLHRPSRTAELKKALKEKENRLLLQSIGETNIEKKIKKKKRSKSVTSSSTSSSDSSASESSSESETSASSSSEDSDSDESLSSSSSSSSSSACSSSSSSSSSSSSSDSDSSSSSSSSSSSSESSSDDEPQKKKKKKK
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 10.
Protein: YCF20_GALSU
Sequence: MQLIIINTLLGIFSSNLLCTIYTQTGDWSLYLTSCIIALYEIISYISYNQFIKKTHKNIINCFNGFKIGLIYGLYLDAFKLGS
What are the official names of this protein?
Uncharacterized protein ycf20.
What is the protein family that this protein belongs to?
Belongs to the ycf20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MAGH1_HUMAN
Sequence: MPRGRKSRRRRNARAAEENRNNRKIQASEASETPMAASVVASTPEDDLSGPEEDPSTPEEASTTPEEASSTAQAQKPSVPRSNFQGTKKSLLMSILALIFIMGNSAKEALVWKVLGKLGMQPGRQHSIFGDPKKIVTEEFVRRGYLIYKPVPRSSPVEYEFFWGPRAHVESSKLKVMHFVARVRNRCSKDWPCNYDWDSDDDAEVEAILNSGARGYSAP
What are the official names of this protein?
Melanoma-associated antigen H1, Apoptosis-related protein 1, APR-1, MAGE-H1 antigen, Restin.
Protein: DHB4_DROME
Sequence: MSSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIESAAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAEASGTLLEVLEKLKEGGGDAIEDAFEFNSKELITYALGIGASVKNAKDMRFLYENDADFAAIPTFFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEIVDDLPTSGTLLTNGKVFDVMDKGSGAVVVTNSESFDESGRLLVRNQSTTFIVGAGKFGGKKDPIAGVVPLQPAPNRQPDATVQYTTSEDQAALYRLSGDKNPLHIDPQMALLAGFKTPILHGLCTLGFSVRAVLAQFADNNPALFKAVKVRFSGPVIPGQTLRVDLWKQGTRINFRTVVVETGKEVISGAYVDLKSSQAKL
What is the function of this protein?
Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids.
What are the official names of this protein?
Peroxisomal multifunctional enzyme type 2, DmMFE-2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RL11_STRA3
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGEPNKTKVATVTRAQVQEIAETKMPDLNAANLESAMRMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SPCS1_CAEBR
Sequence: MDGMIAMLPAPLQQLSSHIDFQGQKVAERTYQVILTLAGIIGFFVGYSTQQLSYAMYTVMGAAVFTALIILPPWPFLFRKNPIVWQTPIEEQEASSSSDNEKKDKKKETKKTK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Dispensable for SPC enzymatic activity (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 1, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PROFU_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEDHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.