PharMolix/UniProtQA huggingface dataset:
Protein: V1R45_MOUSE
Sequence: MSEILFFSPQPLFSHMMNKNSRLHTHSNIKNTFFSEIGIGILGNSFLLLFHILKFIRGHRLRLTDLPIGLLSLIHLLMLLLMAFIATDIFISRRGWDDIICKFLVYLYRVLRGLSLCTTSMLSVLQAIILSPRSSCLAKLKHKYPHHISCAIIFLSVLYMLISSHILLSIIATPNLTRNDFLYVTQSCSILPLSYVMQSMYSTLLALREVFLISLMVLSTLYMVVLLCRHRKQAQHLQGTSLSPKASAEQRATQTILMLMTFFVLMSIFDSIVSCSRTMFLDDPTSYSIHIFVMHIYATVSPFVFMSTEKHIVNILRG
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 45, Pheromone receptor 2, Vomeronasal type-1 receptor A2, mV1R2, Vomeronasal type-1 receptor A9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX4BC_DINQU
Sequence: GLKDWWNKHKDKIVEVVKEMGKAGLNAA
What is the function of this protein?
M-poneritoxin-Dq4b: this synthetic peptide has antimicrobial activity against Gram-positive bacteria B. amyloliquefacies S499 (MIC=0. 1 mM), L. monocytogenes 2231 and S. aureus ATCC 29213, against Gram-negative bacteria P. putida BTP1, P. aeruginosa PaO1 and E. coli ATCC 10536, and against the fungi S. cerevisiae, R. mucilaginosa and C. cucumerinum.  Not active against the fungi F. oxysporum and B. cinerea.
What are the official names of this protein?
M-poneritoxin-Dq4b/U1-poneritoxin-Dq4c/U1-poneritoxin-Dq4d, M-PONTX-Dq4b/U1-PONTX-Dq4c/U1-PONTX-Dq4d, Dinoponeratoxin Dq-3162/Dq-3163/Dq-3178, Poneratoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_STRP4
Sequence: MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_VIBVY
Sequence: MRILGIETSCDETGIAIYDDEKGLLAHKLYSQIKLHADYGGVVPELASRDHVKKTIPLIKEALKEANLTAKDIDGVAYTAGPGLVGALLVGATIGRSLAYAWGVPAVPVHHMEGHLLAPMLEDNPPPFPFVAVLVSGGHSMMVEVKGIGEYKILGESIDDAAGEAFDKTAKLMGLDYPGGPLLSKLAEKGTPGRFKFPRPMTNVPGLDMSFSGLKTFTANTIAANGDDEQTRADIAYAFEEAVCATLAIKCKRALEQTGMKRIVIAGGVSANRRLRAELEKLAHKVGGDVYYPRTEFCTDNGAMIAYAGMQRLKNNEVSDLAVEARPRWPIDQLTPVMK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_BRUAB
Sequence: MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIAGRLLRRVRDFALVAGADIIDRRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PYRF_BACHK
Sequence: MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAAGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGNEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL14_CLOBK
Sequence: MIQQQTRLKVADNSGAKEIMCIRVLGGSHRKWGNIGDVIVASVKSATPGGVVKKGEVVKAVIVRSVKGLRRADGSYIKFDENAAVIIKDDKNPKGTRIFGPVARELRDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CLCN2_HUMAN
Sequence: MAAAAAEEGMEPRALQYEQTLMYGRYTQDLGAFAKEEAARIRLGGPEPWKGPPSSRAAPELLEYGRSRCARCRVCSVRCHKFLVSRVGEDWIFLVLLGLLMALVSWVMDYAIAACLQAQQWMSRGLNTSILLQYLAWVTYPVVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCALGSGMPLGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEELEPPSTSQAWNPPRANVFLTLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGSIERSQVVALLGAQLSPARRRQHMQERRATQTSPLSDQEGPPTPEASVCFQVNTEDSAFPAARGETHKPLKPALKRGPSVTRNLGESPTGSAESAGIALRSLFCGSPPPEAASEKLESCEKRKLKRVRISLASDADLEGEMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSRHGLPREGSPSDSDDKCQ
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport.  Involved in the regulation of aldosterone production.  The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (PubMed:29403011, PubMed:29403012).
What are the official names of this protein?
Chloride channel protein 2, ClC-2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
Protein: Y2327_VIBVY
Sequence: MLRVLGLAGMLMSFNIHAAMISPVSGVKILFANGTEVDEPLEPMEVDAKSAQLVVRYAAELGSGSNQKVFDSAPFVITIDNLSEDIKLYPPKVFSYEQANREFNTSPKWRIEGVSGKEISYSQEKLKGNDGFMPYYGMEALIAKHNEERGIVFSAGVVKAEVVTTDKMVEKPATTKNADALVQLQHWYKQASTEERKAFRKWMVDQE
What are the official names of this protein?
UPF0319 protein VV2327.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: RL22_MESH7
Sequence: MKLENHNLAVASLKTQRISAFKARLVAVLLKGKKVSDALAILAHTKKKASPIFTKLINSAVANAINNHGFEHSNLIIKAAIVNEGPTLKRFRPRAKGAASQILKRTSHFKVILVSQNGGESQNQEYQETEKNLVTKSPENTQSGALSQQSQAEQPQNDPENGVDSQLSAKTNSTTTAKKTDLADNSTKNDATNTVLAQEKEVK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: KITH_STAAS
Sequence: MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHDLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_SALTY
Sequence: MSKRRIAPLTFLRRLLLRILAALAVFWGGGIALFSVVPVPFSAVMAERQISAWLGGEFGYVAHSDWVSMADISPWMGLAVIAAEDQKFPEHWGFDVPAIEKALAHNERNESRIRGASTLSQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGIFGVEAAAQRYFHKPASRLSLSEAALLAAVLPNPIRYKANAPSGYVRSRQAWIMRQMRQLGGESFMTRNQLN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ACCA_BURVG
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLSPWQVSQIARHPQRPYTLDYVAELFTDFHELHGDRAYADDVSIVGGLARFGGHPCMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRLAEKFGLPIFTFVDTPGAYPGIGAEERGQSEAIGRNLYVMAELKTPIITTVIGEGGSGGALAIAVGDTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIINEPLGGAHRDPKGMAALLRRALADSLRQFQGMSIDALRERRFERLMAYGKFKETTPGA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_SOLTU
Sequence: MLPMITEFINYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTISNLPQINNE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HEM1_CHLMU
Sequence: MVREGEEHIDEEFSLGVIGVSYRETALQQREQVLQFLQQAQLSFYPKFPQEEGRSVLLSTCHRVELYGMATEAIFSTLEKEIREMGAIPYFYRNQDCFSHLFCVVGGMDSLVLGETEIQGQVKRAYLQAIEEQKLAFALHFLFQKALKEGKVFRTKRSSPSTEITIPAFVQHELQKQKMARSASLLFMGYSEINRSVAYYLQKQGFSRITFCSRQPLSLRSMDQVLREEVCFQDPYHVIFLGSSELRHAFPRSLWEGVWDFPGRLVFDFAVPRALPVQPACRDRYIDMEQISDWLRQHQKEVFPLQLDSLREVGYRYWESLNRRLARRRYASV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: VORD_PYRAB
Sequence: MNTLFGKAKEEARVISPKSVDEYPEAPITLGTTLVNFTGDWRTFMPVIDESKCVKCYICWKFCPEPAIYIKEDGFVAIDYDYCKGCGICANECPTKAITMVREEK
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorD, VOR, 2-oxoisovalerate ferredoxin reductase subunit delta, 2-oxoisovalerate oxidoreductase delta chain.
Protein: PPZB_METRR
Sequence: MPDNHGPWGLRWRAKPSFILTTVAMGLFTDLVLYGILLPALPFTMRNRFDIPNAEIQHYTSAFLATYAGASVFFSVPAGWAASKLGSRQLFLGGLMFLVVATAIFAFSTSLVLLVVSRLLQGMSTAVVWTAGLDMVQDTVEPSQVGETIGTIFATISVGELAAPVLGGVLYERGGISAVFAVSAVLLAIDLALRALVIDKKTAVKYESPRLIRFPVERNMSDDHVASAPTVMEAQESVHEGTRLLPQVDDDGDHYKIDRELGSIVRAIPLLYCFREPRLHLAMLLSFVQALFIGTFDATVPTVAESLFHFSSLQVGLVFIALMLPYFALGRLSGQAIDRFGTKAAATSGYAFLVPCLMLLGLPEKNLVPKEANVALFCTILALNGIGLAVVTSPGYVEAIDVTTKYQVANPGHFGENGPYAQLFGFSSLYFFTGLAVGPLLGGFLRANFGNAVMGAVYAAISGVTAIVSFLFVGVRRFGPGLV
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of pyrrolopyrazines, secondary metabolites showing insecticidal activity (PubMed:30452111).  Probably involved in the secretion of peramine and other pyrrolopyrazines (Probable).
What are the official names of this protein?
MFS-type transporter ppzB, Pyrrolopyrazine biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPH_CHLCV
Sequence: MRRVILNNPRGFCAGVVRAIQVVETALEKWGAPIYVKHEIVHNRHVVDDLKRRGAIFIEDLSDVPSGEKVVYSAHGIPPEVREEARTRNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIRGEAPESVTVVEKVEDVANLPFEESVPLFFVTQTTLSLDDVAEITQALKVRYPHIITLPSSSVCYATQNRQEALRSVLPKVNFVYVIGDVQSSNSNRLREVAEKRNIPARLVNSPDHISDEILNYSGDIAITAGASTPEHIVQSCISRLKELIPDLQVEEDIFAIEDVVFQPPKELRN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LYSZ_THET2
Sequence: MIVVKVGGAEGINYEAVAKDAASLWKEGVKLLLVHGGSAETNKVAEALGHPPRFLTHPGGQVSRLTDRKTLEIFEMVYCGLVNKRLVELLQKEGANAIGLSGLDGRLFVGRRKTAVKYVENGKVKVHRGDYTGTVEEVNKALLDLLLQAGYLPVLTPPALSYENEAINTDGDQIAALLATLYGAEALVYLSNVPGLLARYPDEASLVREIPVERIEDPEYLALAQGRMKRKVMGAVEAVRGGVKRVVFADARVENPIRRALSGEGTVVR
What is the function of this protein?
Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.  Does not phosphorylate N-acetyl-glutamate.
What are the official names of this protein?
[LysW]-aminoadipate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_NOVAD
Sequence: MTFEVGVVGAGAWGTALAQMLSSDGREVLLWARESEVVREINEDRRNGPFLPSACLNPTITATADLADMARIPVLLLVTPAQHLASVLGGIGRDGGDVVLCSKGIEAGTGRLMADVARDAAPDASIAVLSGPTFAHEVADGLPTAVTLACAGGEEQWLRLSTAIARPTFRPYYSDDVTGAEIGGAVKNVLAIACGVVEGLRLGQNARAALISRGFAEMQRFGLALGARPKTLSGLSGLGDLVLTCSSTSSRNFSLGKALGEGASATAVMADRATVAEGAFTAPVLADLARGRGISMPIVEAVVTLLEGAAPAREVVAGLLSRPLTAENPLV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSP16_CAEEL
Sequence: MSLTADPPACTVPAAGGSSTHKLVNGGADKLIFKIKSSNNNEYRIVPVFGFVDPSGSKDVVITRTAGAPKEDKLVVHFAPAPADATDAQAAFAAVTPAGTVTIPMSATA
What are the official names of this protein?
Sperm-specific class P protein 16.
Protein: NTPPA_BRADU
Sequence: MLGRPKFVLASGSPRRLSLLNQAGIEPDALRPADVDETPKRGELPRACANRLARAKADAALKSVQLDDELRGAFILSADTVVAVGRRILPKANLVDEAAQCLRLLSGRNHRVYTAICLVTPREAFRQRLVETRVRFKRLSEDDIQAYIGSGEWRGKAGGYAVQGIAGSFVVKMVGSYSNVVGLPLYETTTLLGGEGFPIRFGWLNATAV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_BACAC
Sequence: MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKEAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNASIWIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_AAV2S
Sequence: MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQAKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVITTSTRTWALPTYNNHLYKQISSQSGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQGCLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQGVLPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDTNGVYSEPRPIGTRYLTRNL
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, VP2 and VP3 which differ in their N-terminus.  The capsid encapsulates the genomic ssDNA.  Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).  VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.
What are the official names of this protein?
Capsid protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=Capid proteins are first observed in the host nucleolus where capsid assembly may occur, and then are present over the whole nucleoplasm where encapsidation of the viral DNA takes place.
Protein: RPOZ_SHESA
Sequence: MARVTVEDAVEQIGNRFDMILVAARRARQIAVQGKDPMVEEMNDKPTVIALREIELGLVNAHTLDADERQSVREREAAEIAAVAAIAEGRSL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: 3601L_ASFWA
Sequence: MPSTLQALTKKVLATQPIFKDDYCILERCGLWWHEAPITIHHTCIDKQILVKTASFKHGLTLNVALMKAVQENNHDLIELFTEWGADISFGLVTVNMECTQDLCQKLGARKALSENKILEIFYNVKYVKTSSNIILCHELLSNNPLFLNNAQLKLRIFGELDALSINITLDNISFNEMLTRYWYSMAILYKLTEAIQYFYQRYSHFKDWRLICGVAYNNVFDLHEIYNKEKTNIDIDEMMQLACMYDGNYTTIYYCCMLGADINRAMITSVMNFCEGNLFLCIDLGADAFKESIEIASQANNWILINILLFKNYSPDSSLLSLKTTDPEKINVLLDEEKYKSKNMLMYEESLFHIYGTNT
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-1L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: MQO_CORJK
Sequence: MAHKDSVDVALIGAGVISTTLSVMLKQLQPDWSQVIIERLDTPGAESSDPWNNAGTGHSALCELNYTPEVNGKIDISKAVGVNEKFQVSRQFWSYLVEQNVLGDPSEFINKVPHVSFAQGMDQVDYLKARYEALKDHPLFPNMQYSDSDEKFAEFLPLMARGRDFNNPVAISWFDEGTDINYGALTRQYLDAVTAQGVEVRFGNEVKNINRDGSKWKITTKNLHTGDTSMVTANFVFIGAGGMALPLLQKAGIPEIKGYGGFPVSGQWLRCTNPELVEQHQAKVYGKASVGAPPMSVPHLDTRVIDGKKGLLFGPYAGWTPKFLKKGSYLDLFKSLRVGNLPSYLGVGVQEMGLTKYLIEEVLKDQAARVESLREYMPEARAEDWELVTAGQRVQVIKPIGAPKFGSLEFGTALINSNDGSIAGLMGASPGASIAPSAMLEVLERCFGNRIADWAPKLREMIPSYGTRLSKDANLFNEQWDRSQKALKLV
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: LYSY_AERPE
Sequence: MARAVRAGILGASGMTGGELLRILASHPGVEVEWATSREYAGKPVHTAHPHLRGFYTGLKYTSIDKIDIGEVDVVFNALPHGVGASIVAEAYENGVRVVDLSADYRLRDQSLYPKLYGFKHPRPDLLEEAIYALPEIYGEKLRGARLAAVPGCNATAAILAAAPLVASKIIDMDVGIIVDVKAASSEAGSKPSRHSIHPLREGSARPYTPWGHRHAAEAVQVLRDLVGRGIRLSLVPHAVSMTRGVLASAHALLRDNIGFSEAVRAYASFYKDSQIVRVKPMAPGLPVDPPDVKNVIGSMFAEVGFAVEEESGRITGFAAIDNLVRGAAGQAVYAMNAMLGFDEWEGLRSPPLRP
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.