PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_STRLI
Sequence: MAAELHVALVAADREVWSGEATLVVARTTSGDIGVMPGHQPLLGVLESGPVTIRTSDGGTVVAAVHGGFISFADNKLSLLAEVAELSDEIDVHRAERKLEQAKTEGDAHAERRADVRLRAAAGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: B13A_TETBN
Sequence: MQPSYLLLTFAIIFVMVIMYSPAVEAKAGADADADAHADAGCSQFRRMRNLCGGKK
What are the official names of this protein?
U-myrmicitoxin(01)-Tb3a, MYRTX(01)-Tb3, U-MYRTX(01)-Tb3a.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TEFF1_MOUSE
Sequence: MGAQAPLRLPAAPPLAVCGYTSVLLLFAFCLPGSRASNQPAGGGGDCPGGRGKSNCSELNLRESDIRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGEEEGSGAGAHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDVSLLGKKDDGLQYRPDVKDAGDEREDVYIGSHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV
What is the function of this protein?
May inhibit NODAL and BMP signaling during neural patterning.
What are the official names of this protein?
Tomoregulin-1, TR-1, M7365, Transmembrane protein with EGF-like and one follistatin-like domain.
What is the protein family that this protein belongs to?
Belongs to the tomoregulin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYP_STRS7
Sequence: MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRTNLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATSEYKPSSKVTALDDLVEIETPNCKTIDEVAAFLDITEHQVIKTLLFMADHEPVLALLVGNDQINAVKLKNHLGADFLEPASEEEAHTILGAGFGSLGPVHLTDGIRIVADRKIQDLANAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDGHGVLQFARGIEIGHIFKLGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQEAQDLTEKVEASLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF2_SCHPO
Sequence: MKLSTPEEVKAFNRNTYSALFKGALVGSSLGIAGWLIGNRYSAGFRRLPFSLKSWLVIGSGSGASIIFADKAGLKFEAERYGKFDQIDYSTKGLPWNQRALYYFNEHKWPIILGTWASTMGLSLYAASRNRYDTAPQKLIQARMYAQGVTVVVLLGSVYLSTLANRLEPLEREVLVTDPSNPTKLVAFKQRKERYPGELQWEVLVSQDEERLRKLNLPLREPHGSTGPMSTPTPALNSSRSA
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 2 homolog C1565.01.
Protein: SNX4_GIBZE
Sequence: MTATEQQQDDFSNVSWSEHVHDQQTRSVPDAEEPGHDMNAPGTGLERDAPSLGNEKLECTVDTPIKENDGTKDAFVSYLITTHSTFSSFQRSTTTVRRRFTDFVFLYKQLTRDYPAAAVPPLPDKQRMEYVRGDRFGSDFTTRRANSLQRFLSRLSLHPTLRRAPILHTFLESPDWNATMRSRGSRVSSASDPGSAGVFDNFADTFINAFTKLHRPDRRFLEVKEKSDKLDDDLGHIEKVIARVARREADLEVDLRDLAEQFQKLIPLEPHVEPAVHGFSASIEDTASHLRKLKDMTDQDYLGSLRDMQAYSIALKNLLKAREQKQLDYEQLTEYLNKSTTERDTLQSGHGGGSGAGSFLRAKIEDVRGVDHEQARRERTRKLELRVEELTHEVESARKTSDMFDDEVVKEVADFERIKRIEMKAQLGSLADSHIEFYGEVASIWEKYVEEMEKQGITSA
What is the function of this protein?
Sorting nexin involved in the separation or division of vacuoles throughout the entire life cycle of the cells (By similarity).  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures (By similarity). Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures (By similarity).
Protein: TX114_LYCSI
Sequence: MMKALVVVALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A14.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SGBE_HAEIN
Sequence: MLAQLKKEVFEANLALPKHHLVTFTWGNVSAIDREKNLVVIKPSGVDYDVMTENDMVVVDLFTGNIVEGNKKPSSDTPTHLELYRQFPHIGGIVHTHSRHATIWAQAGLDIIEVGTTHGDYFYGTIPCTRQMTTKEIKGNYELETGKVIVETFLSRGIEPDNIPAVLVHSHGPFAWGKDANNAVHNAVVLEEVAYMNLFSQQLNPYLSPMQKDLLDKHYLRKHGQNAYYGQ
What is the function of this protein?
Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).  May be involved in the utilization of 2,3-diketo-L-gulonate.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase SgbE, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: NU5M_BALMU
Sequence: MNLFTSFVLLTLLILFTPIMVSNTDPHKNNKYQSYVKNIVFCAFITSLIPAMMYLHTNQETLISNWHWITIQTLKLTLSFKMDYFSLMFMPVALFITWSIMEFSMWYMHSDPYINQFFKYLLLFLITMLILVTANNLFQLFIGWEGVGIMSFLLIGWWFGRTDANTAALQAILYNRIGDIGLLASMAWFLSNMNTWDLQQIFMLNQNPLNFPLMGLVLAAAGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFYPLMENNKLIQTVTLCLGAITTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTIGLNQPYLAFLHICTHAFFKAMLFLCSGSIIHNLNNEQDIRKMGGLFKALPFTTTALIIGCLALTGMPFLTGFYSKDPIIEAATSSYTNAWALLLTLTATSLTAVYSTRIIFFALLGQPRFPPSTTINENNPLLINPIKRLLIGSIFAGFILSNSIPPVITPLMTMPLHLKLTALTMTTLGFIIAFEINLDTQNLKYTHPSNPFKFSTLLGYFPTIMHRLPPHLDLSMSQKLATSLLDLTWLETTLPKTTALIQLKASTLTSNQQGLIKLYFLSFLITITLSMILFNCPE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL29_SHESA
Sequence: MKASELREKSVEELNAELLGLLREQFNLRMQHATGQLTQTHQLKLVRRNIARVKTIITSKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: MIAA_CLOB8
Sequence: MKQKLLVIGGPTAVGKTDLSIKLAKNLNGEIISADSMQIYKYMDIGSAKVTKDEMNGIKHYLIDAIEPDTPFSVADFKQLGEEALEKIICNGKFPIISGGTGLYINSLTCNMTFTEAEKDESYREYLETLALEKGNEYIHEMLKDVDPISYKEIHANNRKRVIRALEVFKLTNKPFSSYNVGLDFYNSEYDVYYYVLTMNREKLYDRINKRVDLMMEKGLLNECIRLKEMGYNSDIQSMQGIGYKEILYYLEGKITLEKAIDMIKQGSRNYAKRQLTWFRRDKRCIFLDKDIMSDDEILDKVINDIIKN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: BURS_CULPP
Sequence: MISSPSTPATFAAGSLVLLCLVLGGGHFALAQKEGNDDIQHYTADDCQVTPVIHVLQYPGCVPKPIPSFACVGRCASYIQVSGSKIWQMERSCMCCQESGEREASVSLFCPKAKNGEKKFKKVSTKAPLECMCRPCTGIEDANVIPQELAAFADDGTLTSYFQKGQLRNSE
What is the function of this protein?
Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading.
What are the official names of this protein?
Bursicon, Bursicon subunit alpha.
What are the subcellular locations of this protein?
Secreted.
Protein: URK_STRPG
Sequence: MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y748_GLOC7
Sequence: MLIALELSTIWTIALPPITGAIIGYFTNDIAIKMLFRPYKARYIFKRRLPFTPGLIPRNQERLAKRVSDTIMGSLLTPEEIQNLARRLLKTERVQSAILWLLQLAIKQIRADKEQKTAKILAGILSDLFGQSLPRLLKVLARRDDFLEAQINQIFDRILLEFRLTDLQARQLADWLLDTVISPDILRQLLIDFLTDRNIQVIDEGFREKTSGTYWVVANIFGLRNTLTRLRTFCLDEKETANTRLKELLLSLEMRTRLREWLQNLSLQNLPISTVRQLRKTTRDTVRSYIQQSGAQFLQDFNQSIDWEKLAIVVVNRLQASTVVTDSLEMISQELALILERYLEEDLERIVSQAIPILSIDQIIIEKIVATSPKELEAATEGIVKNELQAIVNLGGILGFFVGTIQTVILLLR
What are the official names of this protein?
UPF0754 membrane protein PCC7424_0748.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGBP_PSEAE
Sequence: MKKLALLGALALSVLSLPTFAADKPVRIGIEAAYPPFSLKTPDGQLAGFDVDIGNALCEEMKVQCKWVEQEFDGLIPALKVRKIDAILSSMTITDERKRSVDFTNKYYNTPARFVMKEGASLNDPKADLKGKKAGVLRGSTADRYASAELTPAGVEVVRYNSQQEANMDLVAGRLDAVVADSVNLEDGFLKTDAGKGYAFVGPQLTDAKYFGEGVGIAVRKGDSELAGKFNAAIDALRANGKYKQIQDKYFSFDVYGSN
What is the function of this protein?
Binds L-arginine with high affinity.  Shows no measurable affinity for L-ornithine.
What are the official names of this protein?
L-arginine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PRMA_LACH4
Sequence: MKLLIIKIDTSQEVEDALSIYAMDNLNALGVESRNRSDFEQAGWLHDSTVVDMDDIKDLPKDTYFYAYFDEEADRDELVKKFQDKMQELKGYGLNIGDAKITTSYIEDQDWNTAWQKYYHVINFSRHLAIVPKWEDYKPAFKDQQLIKLDPGLAFGTGNHKTTQLAMMGLERAIVKKPISVVDVGTGSGILAIAASKLGATDILATDISDESMTATEQNSALNDIKNIRVQKTSLLADVDGKFDIIVANILAEILLELIPQMDAHLNEGGQVIFSGIDYLQLPKIEKSLDENGFKIDLTMKQGRWVGLAITRKEK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB11_SOLLC
Sequence: MASNTLMSCGIPAVCPSFLSSTKSKFAAAMPVYVGATNFMSRFSMSADWMPGQPRPSYLDGSAPGDFGFDSLGLGEVPANLERYKESELIHCRWAMLAVPGIIVPEALGLGNWVKAQEWAAIPGGQATYLGQPVPWGTLPTILAIEFLAIAFVEHQRSMEKDSEKKKYPGGAFDPLGYSKDPAKFEELKVKEIKNGRLALLAIVGFCVQQSAYLGTGPLENLATHLADPWHNNIGDVIIPKGIFPN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 6A, chloroplastic, LHCI type I CAB-6A, Light-harvesting complex I 26 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: XK_HUMAN
Sequence: MKFPASVLASVFLFVAETTAALSLSSTYRSGGDRMWQALTLLFSLLPCALVQLTLLFVHRDLSRDRPLVLLLHLLQLGPLFRCFEVFCIYFQSGNNEEPYVSITKKRQMPKNGLSEEIEKEVGQAEGKLITHRSAFSRASVIQAFLGSAPQLTLQLYISVMQQDVTVGRSLLMTISLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVVVLVLFTSVLKTWVVVIILINFFSFFLYPWILFWCSGSPFPENIEKALSRVGTTIVLCFLTLLYTGINMFCWSAVQLKIDSPDLISKSHNWYQLLVYYMIRFIENAILLLLWYLFKTDIYMYVCAPLLVLQLLIGYCTAILFMLVFYQFFHPCKKLFSSSVSEGFQRWLRCFCWACRQQKPCEPIGKEDLQSSRDRDETPSSSKTSPEPGQFLNAEDLCSA
What is the function of this protein?
Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane.
What are the official names of this protein?
Endoplasmic reticulum membrane adapter protein XK, Kell complex 37 kDa component, Kx antigen, Membrane transport protein XK, XK-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IOVO_GALCH
Sequence: TATVDCSGYPQPACSLEYVPFCGSDNKTYSNKCDFCNAVADSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: RBFA_RHOPT
Sequence: MSRQHQKSSPPGGSTRSLRVGELIRHAVAEILAQGGVHDPVLESHLVTVPEVRMSPDLKLATIYVMPLGGRDEKLVIDALEHHKRFLRGEIAHRVNLKFAPELRFRIDERFAEAERIDKLLRSPAVQKDLEPNSDQD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR68_PLAVT
Sequence: MRCVCASIRRTRIIEFLMFFALSSSTASCAPFSVSNVTHASPRPRWLRWHEKTSMAGNPVSLSIATPNGAKSSSICSANTVGFTPDTYTCPDIRDSSTDTLSRSKRISSLSLTKPISSSSESETKVLSAS
What is the function of this protein?
Effector that acts as a broad suppressor of cell death to interrupt plant immunity.  Inhibits cell death induced by cell death-inducing proteins, including the PAMP elicitor INF1 from P. infestans.
What are the official names of this protein?
Secreted RxLR effector protein 68.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: RISB_METVS
Sequence: MVNLGFVIAEFNRDLTYMMEKLAEEHAQFLGANVVCKVMVPGSFDMPLAIKTLLKKDNIDAVVTIGCVIEGDTEHDEIVVQNAARKIADLSLEFEKPVALGISGPGMTRMQAEDRIDYGKSAVEAAVKMVKRINDIKNSN
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TRS31_YEAST
Sequence: MSQRIIQPSASDQQFPGKSDGYEYTVGPKQAITSEASTTYIPSRIYSESLLFKRQEASLSAMAFLFQEMISQLHRTCKTAGDFETKLSDYGHNIGIRLLELLNFRASVSPSSLPRASAFLSQNESSSKLSNASNSPGMLANSSTATSASANERLQEKQTESLSNYITKMRRRDLKILDILQFIHGTLWSYLFNHVSDDLVKSSERDNEYMIVDNFPTLTQFIPGENVSCEYFVCGIIKGFLFNAGFPCGVTAHRMPQGGHSQRTVYLIQFDRQVLDREGLRFG
What is the function of this protein?
Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1.  TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.  TRAPP II plays a role in intra-Golgi transport.  TRAPP III plays a role in autophagosome formation.
What are the official names of this protein?
Trafficking protein particle complex subunit 31, TRAPP subunit 31, Transport protein particle 31 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Preautophagosomal structure.
Protein: ENO_CLOBJ
Sequence: MKNYIEIVDVYARQILDSRCNPTVEVEVELEDGTVGVAAVPSGASTGAFEAVELRDGDKSQYLGKGVLKAVDNVNTTIADELVGMNVLDQVAIDKTMIELDGTDNKAKLGANAMLGVSLACAKAAANSLGMSLYQYIGGVNGKVLPVPMMNIINGGKHADNNVDLQEFMIMPAGAPSFSEALRMCSEVYHALKSTLKAQGYDTGVGDEGGFAPNLKSNEEAIVVIIEAIKKAGYTPGKDIFIALDPASSEIFEDGKYNLAGEGRVLTPEEMANYYVELAEKYPIISIEDGMAEEDWDGWKILTEKIGNKVQLVGDDLFVTNTERLSKGIKLGVANSILIKLNQIGTLTETLNAIEMAERAGYTAVVSHRSGETEDTTIADLVVAVNAGQIKTGAPARSERVAKYNQLLRIEEELNDMGEYRGLKAFYNINK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y5986_DICDI
Sequence: MDRMLETSETFSISGIIENEIEQRESFINDTSKIVELLFKQFNITQQQQQNNENKLINETFSMVFQLFKEMLSPLYSLVNEDMMPNIFELYQMTEDLRYYFALFNGDIKNKLKNITTTTKDLRICNNKKELIKELIKNQYDIDRKPIDQQSISNLRKEEKEKQKENENENENENENENENEKENQELDKKVNQTNDNEKDGDENENEIKDCFFLLFQLFTSIVYNLQSNCEKLLLQSIDISKNNFKRQFYNHLIKRDLNYLENLTFRLNLINDLNKKEEEKEKEKEKEKEENSFDTFSKLFLNDKQQKENTNNIINNNLLESFQIIFSNYIEKNNLNVDLILESFNN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0279685.
Protein: UBP15_BOVIN
Sequence: MAEGGAADLDIQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKYVGFDSWDKYQMGDQNVYPGPIDNSGLLRDGDAQSLKEHLIDELDYILLPTEGWNKLVSWYTLMEGQEPIARKVVEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDTIEKEIRKIFNIPDEKETRLWNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSTPNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFMNSAFQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKYSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSLLSGVPADKMIVTDIYNHRFHRIFAMDENLSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLMAVPRNNTEDKLYNLLLVRMCRYVKISTDTEDTEGSLHCCKDQNINGNGPNGIHEEGSPSEMETDEPDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEETCRGQLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFPLDRETKGASAATGIPLESDEDSNDNDNDIENENCMHTN
What is the function of this protein?
Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling, NF-kappa-B and RNF41/NRDP1-PRKN pathways.  Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear: according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes.  According to another reports, regulates the TGF-beta receptor signaling pathway by mediating deubiquitination and stabilization of TGFBR1, leading to an enhanced TGF-beta signal.  Able to mediate deubiquitination of monoubiquitinated substrates, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  May also regulate gene expression and/or DNA repair through the deubiquitination of histone H2B.  Acts as an inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes cleavage of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains attached by parkin on target proteins such as MFN2, thereby reducing parkin's ability to drive mitophagy.  Acts as an associated component of COP9 signalosome complex (CSN) and regulates different pathways via this association: regulates NF-kappa-B by mediating deubiquitination of NFKBIA and deubiquitinates substrates bound to VCP.  Involved in endosome organization by mediating deubiquitination of SQSTM1: ubiquitinated SQSTM1 forms a molecular bridge that restrains cognate vesicles in the perinuclear region and its deubiquitination releases target vesicles for fast transport into the cell periphery.  Acts as a negative regulator of antifungal immunity by mediating 'Lys-27'-linked deubiquitination of CARD9, thereby inactivating CARD9.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 15, Deubiquitinating enzyme 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: FMT_SALA4
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MIAB_DEHMB
Sequence: MPGYYLWTIGCQMNQAESDRLGRLFELWGYSLADKAEDAELVLVNSCVVREHAENKVVNRLHLLRSLKNENPKLKIALTGCLVGQDISLIKKKFPFVDYIFGPGSMPDWREIPEGFILPLRPPVSANVTIMQGCNNFCTYCVVPYRRGREKSRSIAEIGCEVAELVRRGSREVVLLGQNVDSYGHDLPEKPCLADLLSALHDITGLLRIRFLTSHPKDISQKLIDAMAHLPKVCRSLSLPVQSGDDTILASMRRGYTNQQYRELVERIKTAMPDISLQTDLIVGFPSENEEQFNQSYKLMADIGYDAIHVAAYSPRPQTVAAHDMADDVPVIEKKRRLKLIEDLQKETVGKANAALMDTFAEVLVEGLQKNKWQGRTLGGKLVFLESDLPLEGCLVKVKIFKTSPWSLQAKLVNIMES
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.