PharMolix/UniProtQA huggingface dataset:
Protein: PANSN_PANAR
Sequence: MKTKAVLMLMLLVLVAATLVQGEPEPSYVGDCGSNGGSCVSSYCPYGNRLNYFCPLGRTCCRRSYG
What is the function of this protein?
Antimicrobial peptide.  Has antibacterial activity against Gram-positive bacteria S. aureus ATCC 29737 and B. subtilis ATCC 6633 as well as against Gram-negative bacteria E. coli ATCC 10536 and K. pneumoniae ATCC 10031.
What are the official names of this protein?
Panusin, Defensin-like peptide 7, PaD7.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
Protein: PTH_BUCAI
Sequence: MIVGLSNPKKEYHSTRHNVGSWYLYSLAESYLRNFKNEKKFFGFTTSLNIESNYIRLLIPNIFMNINGQSVFKMASFYNINLSEILIVHDDLELQPGISKLKYSYGHNGHNGLRDIVNTFNKNINFYRFRIGIGRPINRDQIASFVLSNPTKKEKILIQKSILHAIEKNVLSNILKF
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN22_ARATH
Sequence: MKPLVCSFIVILLILLPTTISHDYSDALTKSILFFEGQRSGYLPREQRMTWRHNSALNDGKNLNVDLVGGYYDAGDNIKFHFPMAFTTTMLAWSAIDFGSYMSPADLRDNLVALRWGSNYLLKTVSQLPNRIFVQVGEPTPDHQCWERPEDMDTPRTAYALEAPKPASDLAGEIAAALAAASIAFKRFDPRYSKLLLDNALRTFEYADSHRGSYTNNPETKLAVCPFYCSVNGYEDELLWGAAWLRRATGKDSYIKYLVENRQSFGSDSNYFEFGWDNKVGGVNVLVAKEVFEKNVAAIAPYKDTAEKLMCSFFLETPGAHMSYSPGGLLYKPGSSQLQNTVALSFLLLTYANYLSKSSQQPLQILSTTPLWYLTQRIANIVGFEKVDYILGDNPMKMSYMIGYGNRYPRQIHHRGASSPSITTHPTPVKCSEGWNSFSSPNPDPNVLVGAVIGGPNIDDKFVGGRTNASETEPTTYINAPFVGLLAYFKANPV
What are the official names of this protein?
Endoglucanase 22, Endo-1,4-beta glucanase 22, Glycosyl hydrolase 9B16.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_CAMC1
Sequence: MSNLKDIKRKIKSVQNTQKTTRAMKLVSTAKLRKAEEAARYSRVYALKINEVLSEIAYKINQYASVMTESKFFNTTKSVEKVDIIFVTADKGLCGGFNVQTIKTVRRMIDELKAKKIKVRLRAVGKKGIEFFNFQGVELLETYVGASSSPTYEKAQKIIKDAIDDFTNGITDKVVLIHNGYKNMISQEIRVNDIVPIEPSKIVAVETNSLMEFEPEDNYTKIMDELLNKYFEYSMYYALVDSLAAEHSARMQAMDNATNNAKQRVKQLNLAYNKARQESITTELIEIISGVESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OBG_SHEPA
Sequence: MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQFERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRVLLHILDVEPIDGSDPVEAARAIVAELEKHSPKLAGKPRWLVINKADLMLPEELQERIDRIVKELEWEGDIYTISAYNREGTAELALKLLDFIDSLPPEEEVDADAEVEFKWDNYHQNANDSINEDFNDDFDDDFDEDDYDVEIIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_STRP3
Sequence: MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLIEKTVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO2_STAAN
Sequence: MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVNVEVVSEEAGVLSEQLASEGDTVEVGQAIAIIGEGSGNASKENSNDNTPQQNEETNNKKEETTNNSVDKAEVNQANDDNQQRINATPSARRYARENGVNLAEVSPKTNDVVRKEDIDKKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEVDMTNVMELRKRKKEQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
What is the function of this protein?
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: HLDE_ALCBS
Sequence: MQNPHIPSFAQARVLVAGDVMLDRYWHGPTSRISPEAPVPVVRVTELEDRPGGAANVALNMAALGARAELVGVTGRDEAASILEERLAAAEVGCHFQKVDGLPTITKLRVISRQQQLLRLDFEEAFHSQDPAPFAEQVKQQLVHCGALVLSDYAKGALRDCPGLIALAREAGVPVLVDPKGTDFEPYRGATLLTPNLSEFEAVVGVVKDEQDLIAKGQQLIRDLDLQAMLVTRSEKGMTLLRDGLPELHLPARAREVFDVTGAGDTVISVLAVSLAAGAAMEDAVALANIAAGIVVAKLGTAVVSAPELRRAVHQEGGSGRGVMSEAQLLIAIEDARAQGERIVFTNGCFDIIHAGHVGYLDTARRQGDRLVLAVNGDESIRRLKGPGRPINPLERRMAVLAALEAVDWVVAFDTDTPEPLLESIKPDVLVKGGDYSVDQVVGHEFVKSYGGEVKVLDFIDDISTTKIVERIREKD
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: ACO11_HUMAN
Sequence: MIQNVGNHLRRGLASVFSNRTSRKSALRAGNDSAMADGEGYRNPTEVQMSQLVLPCHTNQRGELSVGQLLKWIDTTACLSAERHAGCPCVTASMDDIYFEHTISVGQVVNIKAKVNRAFNSSMEVGIQVASEDLCSEKQWNVCKALATFVARREITKVKLKQITPRTEEEKMEHSVAAERRRMRLVYADTIKDLLANCAIQGDLESRDCSRMVPAEKTRVESVELVLPPHANHQGNTFGGQIMAWMENVATIAASRLCRAHPTLKAIEMFHFRGPSQVGDRLVLKAIVNNAFKHSMEVGVCVEAYRQEAETHRRHINSAFMTFVVLDADDQPQLLPWIRPQPGDGERRYREASARKKIRLDRKYIVSCKQTEVPLSVPWDPSNQVYLSYNNVSSLKMLVAKDNWVLSSEISQVRLYTLEDDKFLSFHMEMVVHVDAAQAFLLLSDLRQRPEWDKHYRSVELVQQVDEDDAIYHVTSPALGGHTKPQDFVILASRRKPCDNGDPYVIALRSVTLPTHRETPEYRRGETLCSGFCLWREGDQLTKCCWVRVSLTELVSASGFYSWGLESRSKGRRSDGWNGKLAGGHLSTLKAIPVAKINSRFGYLQDT
What is the function of this protein?
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
What are the official names of this protein?
Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, Palmitoyl-coenzyme A thioesterase.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cytoplasm.
Protein: DNLJ_BRUME
Sequence: MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALAIFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFKKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: THOC7_DROME
Sequence: MSEQCQLRPHSDTLVRKLVEMNDEEIIKQRLLIDGDGTGEDRRIVVLLKQFLKWASDSLDSNPIMYDRLMAQFAQCKLTALKNVQTLQMIAGERDNYTQLVEHHEESIVLAKAEIESSKKELITAKQIRKNKMEYDLLASLIQDQPDRSETQRHIETIRREIDDLVQKKLKMERKFQKRRNDFTLLMYTIHELEQQLDQDSSSSASSSSSDCDARSEPDLDDNGIMEVSDEDDDLNNSTPTKFDGARGEPKYHSVSTEDSKAMSVEEDTVLELSIDKDEHDVDVAVAN
What is the function of this protein?
The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress.
What are the official names of this protein?
THO complex protein 7.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle.
Protein: LIPG_BOVIN
Sequence: MWWLLVTVCFIHMSGNAFCFLGKIAKNPEASMNVSQMISYWGYPSEMHKVITADGYILQVYRIPHGKNNANHLGQRPVVFLQHGLLGSATNWISNLPKNSLGFLLADAGYDVWLGNSRGNTWAQEHLYYSPDSPEFWAFSFDEMAEYDLPSTIDFILRRTGQKKLHYVGHSQGTTIGFIAFSTSPTLAEKIKVFYALAPVATVKYTKSLFNKLALIPHFLFKIIFGDKMFYPHTFLEQFLGVEMCSRETLDVLCKNALFAITGVDNKNFNMSRLDVYIAHNPAGTSVQNTLHWRQAVKSGKFQAFDWGAPYQNLMHYHQPTPPIYNLTAMNVPIAVWSADNDLLADPQDVDFLLSKLSNLIYHKEIPNYNHLDFIWAMDAPQEVYNEIVSLMAEDKK
What is the function of this protein?
Catalyzes the hydrolysis of triacylglycerols to yield free fatty acids, diacylglycerol, monoacylglycerol, and glycerol (PubMed:8615791).  Shows a preferential hydrolysis at the sn-3 position of triacylglycerol (By similarity).
What are the official names of this protein?
Gastric triacylglycerol lipase, GL, Gastric lipase, Pregastric esterase, PGE.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_RHOPS
Sequence: MALRLYDTLTKEKRDFAPLDPSRVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHLYGENHVKYVRNITDVDDKINDRAARDYPGLPLNESIRKVTEQTERQFHDDVDALGCLRPTVEPRATEHIGEMRTIIDRLVEGGFAYVADDHVLFSPGAMNAADSVLPRYGALANRSLDEMIAGARVDVAPYKRDATDFVLWKPSKPGEPSWPSPAGIATQGRPGWHIECSAMSWKHLGETFDIHGGGIDLVFPHHENEVAQSCCAFHTSRMAQTWMHNGFLQVEGEKMSKSLGNFVTIRELLATEKFGGRKWDGATLRLAMLKTHYRQPIDWTADALHEAEKAIFDWSDFTKDATPGSCDDVIAALTDDLNTPKMIAELHALRRAGKADELCGAMELLGISPVVRGTVDLDATAKSLIDARTAARARKDFKESDRIRDELAAMGIAIKDGKDSDGKPVTTWEIAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BACSU
Sequence: MTTRKESELEGVTLLGNQGTNYLFEYAPDVLESFPNKHVNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDEKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPETIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway.
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_AZOPC
Sequence: MKNVAIVSGGYSSECVISLKSAEEVYLSIDKTRYNPYIVLITRNGWTVQGGNKTEFPINKNDFSFIYKGKQIRFDFAYIIIHGTPGEDGLLQGYLDILNIPYSCCGVLSASITFNKYFCNNYLRGFGVETAKSILLKQREQIISPERIIDKLGLPLIVKPNDGGSSFGVTKVTNITQIQLAIRNAFNEGEGVLIESFIPGTEITCGYYKTKNKQVTLPITEIISKNDFFDFEAKYNPGMVEEITPARISKKLTDEIQTLTAHIYDWVGAKGIIRIDYIISPKKEIKMLEVNTIPGMTATSFIPQQIRAAGLNLKEILTEIIESI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_RHORT
Sequence: MRPSGRAVDSLRSIVLEPGYSKHAEGSCMARFGDTHVLCTASIEERVPGWMRGGGKGWVTAEYGMLPRSTHTRTDREAARGRQSGRTQEIQRLIGRSLRSVTDLKKIGEIQIRLDCDVIQADGGTRTAAITGSWVALYQALARFEKLGLGALPPLTDHVAAVSCGLCDGVAVLDLDYAEDSTAQADANFVLTGTGGIVEIQGTAETSPFAQAQFMELLALAQKGITELVALQKAALASLR
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GRPE_BORPE
Sequence: MTAPQEPVDSTPESGENAATPGLEDDLSAELAALRAELEAAQATVKAQQEQVLRAAAEAENVRRRAQEDVAKARKFGIESFAESLVPVKDSLEAALAQPDQAAQAWREGVEVTLKQLTAAFERNLLKEIAPAQGDKFDPHLHQAISSVPADQPANTVLQLLQKGYVIADRTLRPALVVVSAGQG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAF1_ARATH
Sequence: MGFFDLSIPYNEPPRSGGKEIAGGKTLRLKLATKAMELGYVGIAHNRSIKGVMSDKDSCTIPLLTLGSLIKVAPRLASSVGFHRDLLGVPRTTPFRQYTRLTVHVESNAQCQSLNSGNPILKSYDIIAVRPMNQNAFDYACEKAEVDLISIDFTDKMLFRLKHPMVKAAIQRGIYFEIKYSDILMDAQTRRQVISNAKLLVDWTRGKNLIISSGAPSVTELRGPNDVINLMFLLGLSAERARAAISKNCRNMIAKVLKKKRFHKEAVRVELLSAGDTFSLEQPLSEDCMKWDRLSSGEGDMLLDDLAKAFDATNVVAHKSSKAIDFTSVLDGLPKHGFRVKDIVGTESVTQPSAAKVIDTQVHSSNQVSELRMATASSDDNLREIETISQIDMLMSEDDNKVEPTTNVLKEEAFALRKCSASHGQGILVQNQTATPFTLTRCTKSEAASDVSMNIESTSEGGSMSPSKSDHGIPQSPVEVNNMGNAAFEEEASVDENSKERATTGHASNDEMHITESGHHASIDDEKHIPEPEHLTSIADEMKIDCSSEANHDEYMEVTMEDQMHETVQMRLCKTMTKHQD
What is the function of this protein?
Probable component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (By similarity).  May also be a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (By similarity).  Required for female gametophyte development and male competence (PubMed:22509260).
What are the official names of this protein?
Protein GAMETOPHYTE DEFECTIVE 1, Probable ribonuclease P protein subunit p30, AtRPP30, RNaseP protein p30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Mitochondrion.
Protein: DPH4_SCHPO
Sequence: MNHYSVLNLKDGKTYTDDEIKEAYRKALLLFHPDKCKEKPSVVYTIDQVKEAYQVLSSEKDRQQYQIKQEEESSHYYSIVDLSEFEELDNGSYYYPCRCGDLGGYVVTEDDLENNRSVVPCMGCSLTIQVDYEIAESDS
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue.  Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).
What are the official names of this protein?
Diphthamide biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the DPH4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPG_WOLWR
Sequence: MLDKDLILNDNTYELSQISRHKTHVVEVGKVKIGGNNPVVVQSMALGVHIDADNIKSSAKHYAKEITELARTGSELVRIALNSEEVARAIPYIVEEINKEGFDGKILVGCGQYELDKLVQDYPDNIKMLGKIRINPGNIGFGDKRDEKFERVIEYAIMHDLPVRIGVNWGSLDKYLLQKLMDENSSLSNSRPSDVILRKALVMSALDSAKKAEGIGLNSNKIIISCKVSKVQDLILVYMALAKSSNYALHLGLTEAGMGNKGVVNTAAGLTYLLQNGIGDTIRASLTQRPGESRTNEVVVCQEILQSIGLRYFNPQVNSCPGCGRTSSDRFRILTEEVNGYIKTHIPIWKKKNPGVEHMSIAVMGCIVNGPGESKHANLGISLPGYGEKPVSAVYKDGKYFKTLQGDNVSEEFKAIIDNYVKEHYT
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RUTD_CAUVC
Sequence: MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRGTGRSVRELPPRYTLAHMADDMVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLVVVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLYPADWISRNHTRLMAEEAHHVAAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADFQQVAWGGHGFTVTDPETFNEALVSFLEGA
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: CH60_BACAN
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLVGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENI_LISM4
Sequence: MGLQETIGIEIVSVEKGKAVVQLEVTEKVHQPFGYLHGGVSVVLAEHAASIGAAKSIEPDEIVFGLEINANHLASKQAGLVTATAEAIHIGKSTQVWEIKITDETEKLLCISRCTIAVKKKRK
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA) and free coenzyme A (PubMed:33619030).  Production of DHNA is required for protection against bacteriolysis in the cytosol of macrophages and tissue-specific virulence in vivo, suggesting that MenI is required to protect the bacteria from killing in the macrophage cytosol (PubMed:33619030).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, 1,4-dihydroxy-2-naphthoyl-coenzyme A thioesterase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: GBRA2_RAT
Sequence: MRTKLSTCNVWFPLLVLLVWNPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNSMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNPSDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKGSVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVLGVSP
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha2/beta2/gamma2 receptor exhibits synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Cell projection, dendrite.
Protein: OFP14_ARATH
Sequence: MPNPLQKSLHGYLSKIKKETGKLQLSSSHSFSSSKNWVLGKHPKKLSFSFKHRRRSSKTRFSKEEPVYHQDSAHAATLSDIDRFLEENFKSLCIRDDQEDDQHQARVTKNKEKRESSSDDSDDDDDDDDYRHRFERTWGHAVYDSPKQPPDLLRTERLSPPPGSSEGRPSMETTSTSSERQSRSTLVLPENCIAVLRYTDEPQEDFRQSMVEMMESKLGMRESEVDWDLMEELLFCYLDLNDKKSHKFILSAFVDLIIALREKEKRITRKGHVRSLSTRAARDRLRKRMIMSDN
What is the function of this protein?
Transcriptional repressor that may regulate multiple aspects of plant growth and development through the regulation of BEL1-LIKE (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
What are the official names of this protein?
Transcription repressor OFP14, Ovate family protein 14, AtOFP14.
What are the subcellular locations of this protein?
Nucleus.