PharMolix/UniProtQA huggingface dataset:
Protein: LACD2_STRP3
Sequence: MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLIYYDIDGGQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEILFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase 2, D-tagatose-1,6-bisphosphate aldolase 2, Tagatose-bisphosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: MOAA_RHILO
Sequence: MNMIDPFGRTISYLRVSVTDRCDFRCTYCMAEDMAFLPKKDLLSLEELDRLCSVFIEKGVRRLRLTGGEPLVRKNIMHLVRQLSRHLDSGALEELTLTTNGSQLSRFAAELADCGVKRINVSLDTLDADKFHQITRWGHLDKVMQGIDAAQAAGLKVKLNAVALKDFNDAELPDMMRWAHGRGMDLTVIETMPMGEIDADRTDQYLPLSLLRASLERQFTLTDIPFKTGGPARYVHVAETGGKLGFITPMTHNFCESCNRVRLTCTGTLYMCLGQEDAADLRAPLRASEGNELVADAIDEAIGRKPKGHDFIIDRRTSRPSVSRHMSVTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RPOZ_CHRVO
Sequence: MARITVDDCLDRIQNRFDLTLAAAYRARQVASGASAFVEPGRHKPTVIALREIAAGHVGKEVLNRGKA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: OPCM_BOVIN
Sequence: MGVCGSLFQPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDVTVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGMRIENKGHISTLTFFNVSEKDYGNYTCVATNKLGITNASITLYGPGAVIDGVNSASRALACLWLSGTLFAHFFIKF
What is the function of this protein?
Binds opioids in the presence of acidic lipids; probably involved in cell contact.
What are the official names of this protein?
Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: IDI_JANSC
Sequence: MTIHIPTWVNGTLQPVEKLEAHLRGLRHKAISVFILRDGDVLLQRRAMGKYHTPGLWANTCCTHPQWDEAGVDCAMRRLDEELGVKDVPLRYRDTVEYRADVGGGLIEHEVVDIFVGEMPSGMEPVMNPEEVMEVEWTPLATLAQRVEASPETFTPWLHIYLRKYADIIFESATDA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEC1_ARATH
Sequence: MDSDIMNMMMHQMEKLPEFCNPNSSFFSPDHNNTYPFLFNSTHYQSDHSMTNEPGFRYGSGLLTNPSSISPNTAYSSVFLDKRNNSNNNNNGTNMAAMREMIFRIAVMQPIHIDPEAVKPPKRRNVRISKDPQSVAARHRRERISERIRILQRLVPGGTKMDTASMLDEAIHYVKFLKKQVQSLEEQAVVTGGGGGGGGRVLIGGGGMTAASGGGGGGGVVMKGCGTVGTHQMVGNAQILR
What is the function of this protein?
Required for the female reproductive tract development and fertility.
What are the official names of this protein?
Transcription factor HEC1, Basic helix-loop-helix protein 88, AtbHLH88, bHLH 88, Protein HECATE 1, Transcription factor EN 118, bHLH transcription factor bHLH088.
What are the subcellular locations of this protein?
Nucleus.
Protein: BLA2_BACCE
Sequence: MKKNTLLKVGLCVGLLGTIQFVSTISSVQASQKVEKTVIKNETGTISISQLNKNVWVHTELGSFNGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMKVETFYPGKGHTEDNIVVWLPQYNILVGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK
What is the function of this protein?
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.  Active on cephalosporin and penicillin.
What are the official names of this protein?
Metallo-beta-lactamase type 2, B2 metallo-beta-lactamase, Beta-lactamase II, Cephalosporinase, Metallo-beta-lactamase type II, Metallothioprotein beta-lactamase II, Penicillinase, Zinc-requiring beta-lactamase II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CDC20_MOUSE
Sequence: MAQFVFESDLHSLLQLDAPIPNAPVARWQRKAKEATGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRFIPQRSASQMEVASFLLSKENQPEDRGTPTKKEHQKAWSLNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTSHSARVSSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWAPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTARVLGLTMSPDGATVASAAADETLRLWRCFEMDPALRREREKASVAKSSLIHQGIR
What is the function of this protein?
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex.  Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.  The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.  CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
What are the official names of this protein?
Cell division cycle protein 20 homolog, mmCdc20, p55CDC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.
Protein: N42L2_HUMAN
Sequence: MSYGEIEGKFLGPREEVTSEPRCKKLKSTTESYVFHNHSNADFHRIQEKTGNDWVPVTIIDVRGHSYLQENKIKTTDLHRPLHDEMPGNRPDVIESIDSQVLQEARPPLVSADDEIYSTSKAFIGPIYKPPEKKKRNEGRNEAHVLNGINDRGGQKEKQKFNSEKSEIDNELFQFYKEIEELEKEKDGFENSCKESEPSQEQFVPFYEGHNNGLLKPDEEKKDLSNKAMPSHCDYQQNLGNEPDKYPCNGQVIPTFCDTSFTSFRPEWQSVYPFIVPYGPPLPSLNYHLNIQRFSGPPNPPSNIFQAQDDSQIQNGYYVNNCHVNWNCMTFDQNNEYTDCSENRSSVHPSGNGCSMQDRYVSNGFCEVRERCWKDHCMDKHNGTDRFVNQQFQEEKLNKLQKLLILLRGLPGSGKTTLSRILLGQNRDGIVFSTDDYFHHQDGYRYNVNQLGDAHDWNQNRAKQAIDQGRSPVIIDNTNIQAWEMKPYVEVAIGKGYRVEFHEPETWWKFDPEELEKRNKHGVSRKKIAQMLDRYEYQMSISIVMNSVEPSHKSTQRPPPPQGRQRWGGSLGSHNRVCVTNNH
What are the official names of this protein?
NEDD4-binding protein 2-like 2, Phosphonoformate immuno-associated protein 5.
Protein: PHR_POTTR
Sequence: MDSKKRSHSTGGEAENMESQESKAKRKPLQKHQFSKSNVVQKEEKDKTEGEEKGAEGLQEVVRQSRLRTAPSVLEFRFNKQRVRLISQDCHLQDQSQAFVYWMSRDQRVQDNWAFLYAQRLALKQKLPLHVCFCLAPCFLGATIRHYDFMLRGLEEVAEECEKLCIPFHLLLGLPKDVLPAFVQTHGIGGIVTDFSPLLHHTQWVKDVQDALPRQVPFVQVDAHNIVPCWVASDKQEYGARTIRHKIHDRLPHFLTEFPPVICHPYTSNVQAEPVDWNGCRAGLQVDRSVKEVSWAKPGTASGLTMLQSFIAERLPYFGSDRNNPNKDALSNLSPWFHFGQVSVQRAILEVQKHRSRYPDSVTNFVEEAVVRRELADNFCFYNKNYDKLEGAYDWAQTTLRLHAKDKRPHLYSLEQLESGKTHDPLWNAAQMQTVKEGKMHGFLRMYWAKKILEWTRSPEEALEFAIYLNDRFQLDGWDPNGYVGCMWSICGIHDQGWAEREIFGKIRYMNYAGCKRKFDVAEFERKISPAD
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-2 family.
Protein: SYK_SHEPA
Sequence: MTEQTQDENKLIAERRAKLEHIRTNCPANGHPNNFDRKHKAADIQAEFGHNTKEELEGMGIERSIAGRVMAKRGPFLVIQDVSGRIQAYAGKDVQKDLKEKFLGLDIGDIIGVTGQLHLSGKGDLYVNMEEYQLLTKALRPLPEKFHGLTDQETRYRQRYVDLIVNEDSREAFIMRSKVVSAIRNFMVKKEFMEVETPMMHSIPGGASARPFETHHNALDIAMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADFNDLMDLTEEMLSSIATELCGSPQLPYGEHTVDFGGPYARLSMLDAIKKYNPDNATIQSMTYEEVKDVEFMRDLAKSLGMTVEKFWTCGQLLEEIFGETAETQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVANGFSELNDAEDQDSRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQAN
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_CHLRE
Sequence: MIFDFNYIHIFMLTITSYVGLLIGALVFTLGIYLGLLKVVKLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL20_ACISJ
Sequence: MPRVKRGVTARARHKKVLALAKGFRGRRGNVFRIAKQAVMKAGQYAYRDRRTKKRVFRQLWIARINAAARELGLTYSQFANGLKKASIEIDRKMLADLAVHDKAAFGSIVEQVKAKLAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RRP36_MALGO
Sequence: MHLRDSTKDTLASSGNRDDDEIDDGQHAQFLDADTVDSEESIEAEPVEENEEWSDQGSGAEGSDEGGGYAQYIDPDDDIDENDEEGMEVSGNDEEENSDHEEVRILVLLNSGYITAWYILAQCTDAEIESVPYDKLLKARRIMRRQSARGHATDEEDDNEHESIEAKRDLAKKKLREMYLSSHSSSSKPKLPPTSSSSSFLASRERKNAPAVMSSRRPVSRLRQVVKPIQNAKARDPRFDSLSAGPVNLDLHAKSYGFLPDLYQTEIKQLRDQHAKLKRTEIHHAGPRAKSQQAAEIRDQRAHVEQELRRAESRQNERTRRERERSVKADFKKENQRRVDAGLKPFFPKKAQFQEALLRKQFDEMAQGSGTGSSASLRKAMDRKRRKDAQKEKKSLDAALGGGSRTDIRPMRHFSDAPRPHKRGRRG
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CPXS2_SYNY3
Sequence: MDAMEFFRNSSGNWRSQRTTHHLAFRRAETGTSEIFVEALGADDQKIVEICEMHDCDPAKAVGGAFVRWESAMAWDKEDENHEGTTVFALIPDEDNPQQGLLLRERGYAEIVPIAGRYHIDEEEALVLVTEYETMTTIERFWFANPDMRLRTSTVQRFGGFNTATYCTEMRVKEENTVSASPAPAYEQFCGW
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcS/CpeS 2.
What is the protein family that this protein belongs to?
Belongs to the CpcS/CpeS biliprotein lyase family.
Protein: TRUD_DEIRA
Sequence: MTGRRCERTTSPGTGGRLRAEPADFQVQEVPAYLPGGSGEYLYLHVEKTRHTTAHVVRELCAQLGVRDRDVGVAGLKDRHAVTTQWLSLPAKVEPRMGDFSLPGVRILETSRHTNKLGMGHLHGNRFVVRVRGAAGMAEQAGETLATLAQGGVPNYFGPQRFGLGGLNAEEGLRVLRGESELRDPRVRRFLTSSVQSAIFNALVSLRLEREVFDRLLTGDMAKKHDTGGVFLVEDAGAETPRAQRGEVSATGTLFGRKVKPLTADAGALEAEALALFGLSPQVFASRKGDRRLIRVFPAEAEVRPEDDGYVLAFTLPKGSFATSVLREVMKTEVDAPGAGPDTTDEGEAGDGE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: TRMD_PORGI
Sequence: MRIDIITVLPEMIENTLNCSIIGRAQERGLLELKLHQLRDYSTDKWKRVDDYPFGGEPGMVMQIEPIDRIITELKTQREYDEVIFTSPDGERFDQPMANELSLLSNLIVLCGHYKGIDYRIREHLITREISIGDYVLTGGELAAAVMTDAIARLIPGVLNDAGSALSDTFQDNLLAPPVYTRPAEYKGWRVPDILLSGHEANIAKWRLEQAVERTKRLRPDLIKD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_YERPB
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDFVRVKEDVAAQEANNSTLKARNDQLFAEIDDLNGGQEAIEERARNELGMIKPGESFYRLVPDQSRRNAGTPSTQNNAQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: XENB_XENSI
Sequence: MGSNLAGTQCLDSLDFVLQGGAIDDEQLRITPPEDCFDVNFDFISPPVPRTMPDFGIYEFGSEATSGSLEPGPFMPIEHAATSNPAAEKPNPGALVHVSSMQQESVEQMSALNVEIHRQLSVVSQVAKEYATTEPSLMDSTDQRNRLSSAVVSMIQGLQTFQTLLLEILGAARQGSPKEPASRASMHSSQKNDTSLQTSWTWLNTKNDLSSIADADTGDTISDFETGDRQTISRSDTNSEVRPIPESPSQTTWLDMSTSLLIISCYINLIQLCRDVFAAIRGALSVPGHQTTLLELSGFQISGVSIHEDSDLQIIVLTQVVVRLIDRIGLYLGYSGTSTAEAGKRDESDFNCKTISPQLLDFVLGQKEMEGQPSCKERIEALREEIRKLSEVVYKPI
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of xenoacremones such as xenoacremone A, a compound that shows inhibitory activity toward the PI3K/AKT signaling pathway and which has the ability to induce apoptosis of A549 lung cancer cells (PubMed:34900544).  Acts as a positive regulator of the xenoacremones biosynthesis gene cluster (PubMed:34900544).
What are the official names of this protein?
Transcription factor xenB, Xenoacremones biosynthesis cluster protein B.
Protein: RNPA_PROMT
Sequence: MVLPKHMRLKGHRCFDFIYKEGSRFYSSSMVLRVTDANKKPQVKGKQSKTRHSIKCAISISNKVSKKSVTRNKLRRLFHHHLSLRLSNMACDNEIWAFISLKPSCMKNPDSTLLKECDKLLTKAGITK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SYT_SHEWM
Sequence: MPVITLPDGSKREFATPVSTLDVAADIGPGLAKACIAGRVNGELKDACDIIDTDSELSIITAKDEEGVEILRHSCAHLLGHAFKQLWPEAKMAIGPVIDNGFYYDIDLDHKLTQEDIDALEKRMVQLAKTNYIVEKRVGSWQVARDTFEARGETYKMEILDENISKDDQPALYHHEEYVDMCRGPHVPNMKFCQHFKLMSVAGAYWRGNSDNKMLQRVYGTAWADKKALKVHLNRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSLFLELEKFIRQKLGQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTNSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHVFCTEDQVQQEVSACIKMVYDTYETFGFKDIVVKLSTRPEKRIGDDDMWDRAEEALKQALTANDIAYEILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPGRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGKFPTWLAPMQAVVMNITDKQSDYVDEVVNILKENGIRASKDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGVDLGKIQISEFASKIKEQISLRSLNLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_VIBVU
Sequence: MYMSTDEVRNAFLKFFESKGHQIVDSSSLVPHNDPTLLFTNAGMNQFKDCFLGAEKRAYTRATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKEDAIAFAWEFLTETLKLPKDRLLVTVYETDDEAFDIWNQKVGVPADRIIRIGDKKGGKQYESDNFWTMGDTGPCGPCTEIFYDHGEHIWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERISAIMQGVHSNYEIDVFQKLIKATAEIVGCEDLSNQSLRVIADHIRSCSFLIADGVMPSNEGRGYVLRRIIRRAVRHGNKLGAQGVFFHKLVGVLAEAMGSAADELKKQQAVVEKVLRIEEENFGRTLERGMVILNEALDALEGKELDGETVFKLYDTYGFPADLTNDVAREREFTIDEAGFEKAMEEQRQRAREAGQFGTDYNAKIKVDAQSEFCGYTSTQERSDVVALFVEGEETATLSAGDKAIVILQETPFYAESGGQCGDSGVLKTESGLFQVEDTQKLGNAIAHHGVLVEGVLAKGDQVTAIVDAERRAAISLNHSATHLLHAALRQVLGEHVAQKGSLVKAENLRFDFSHLEAVTAAELKEVERLVNAQIRRNHAIETNIMDIESAKQKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASNTGDIGLFKITSEGGIAAGIRRIEAVTGEAALEAIDAQARKFEEKLQDAANKAKSLEKEIQQLKDKLASQASANLIDQVKEIAGVKVLVAKLDGADNKALRGMVDELKNQMGSGIIMLGNVADDKVGLIAGVTQDLTSKVKAGELVNMVAQQVGGKGGGRPDMAQAGGTDSSALPSALASVDAWIAERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_CLOBJ
Sequence: MKVLNNLLYTGDHEWIRVEDNKAYIGISDCAQRMLSDIVFVELPEVDDEIAKGETFATIESVKAASDSYMPVSGTIVEINEELEDNPAALNEDPYGSWIIAVEMSDKSELEELIKPEVYEKICEELDKEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HMUV_MYXXD
Sequence: MSLEVRGIEVWRGRGRTLGPMDLTLEPGEVLAVVGPNGAGKSTLLSAMSGELRCSTGEVLLDGTPLLQWKPRERAMRLGVLPQESSLGFGFTALEVALLGRSPHSSRAEGSADLAAAVAALDATDTRHLASRSYLTLSGGERQRVQLSRVLAQLSEPLASGHRYLLLDEPTASLDLAHQHLVLEAAARFAQAGGAVLAVLHDLNLAARYAHRMAVLAEGRVVELGAPAQVLSQELVARVFGLRVQVVEWPGSPGPLVIPEGRAPLTP
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COX41_PITPI
Sequence: SVVKSEDYTLQSYVDRRDYPLPDVAHVRHLSASQKALKEKEKASWSSLSMDEKVELYRIQFKESFAEMNRGSNEWKTVVGAAMFFIGFTAILIMLEKRYVYGPLPHTFDKEWVAMQTKRMLDLKVNPVDGLASKWDYEKKEWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NPD_CAMJR
Sequence: MKNIMILSGAGLSAPSGLKTFRDNDGLWEEYDVMEVCSATGFRKNPKKVLDFYDARRVQLQNVKPNHAHEKIAQLKEKWGKNLFVITQNVDDLLERAGCKDVVHLHGFLPELRCLKCEGIFNIGYEKIIDKQCPKCKSKDLRHNIVMFEEQAPAYATLYSLLNQTSLFISIGTSGAVLPVGRYASMCEKSILNIYEKDANLERYFDKIYIEDIINAIDKIALDIENFMKDGNV
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_EHRRG
Sequence: MNDNYMINPKKELSQCFIHSTDITDKIVNYAGNISNFSIIEIGPGLGTMTYSILKKNPKKLISIEKDSRLLPIHDKIIKEFQGKYEFILSDALDIDLRNIAKPPVKVIANLPYSIATLLLIKWINYINFFHSFTLMFQKEVADRIIAQPNNKNYGTLSILTQLFADVYKMQDFGPEIFSPKPKVFSSVINIVVLPQPRFDVNYDKLRKIVKITFNQRRKMIRSTLKQITNNTDEILHSLNIPNNLRPENLSIKQFCDIANCI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_YERPA
Sequence: MSRVAKAPVVIPAGVEVKLNGQVISIKGKNGELTRTVHSAVEVKQEENTLTFAPREGAVDGWAQAGTTRALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLALGFSHPVDHELPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.