PharMolix/UniProtQA huggingface dataset:
Protein: OTU1_HUMAN
Sequence: MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVLQGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLIIEEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins.  May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore.  Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel.  Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.  Cleaves both polyubiquitin and di-ubiquitin.  May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.  May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation (PubMed:27753622).
What are the official names of this protein?
Ubiquitin thioesterase OTU1, DUBA-8, HIV-1-induced protease 7, HIN-7, HsHIN7, OTU domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: OGT_SHIFL
Sequence: MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDIHYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPCGQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKEWLLRHEGYLLL
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_XANAC
Sequence: MPNIDTATMTPREIVQELDRHIVGQHDAKRAVAIALRNRWRRMQLPEELRNEVMPKNILMIGPTGVGKTEIARRLATLANAPFVKVEATRFTEVGYVGKDVEQIIRDLADTAVKLYREQAKVRVRNQAEERAEDRILDALLPRRATGIGFDPEAARNEPSSQDNDTRIKFRRMLRNGELDEREIELEVAVNASMDIMTPPGMEEMGQQLRQMFSNLGSGKSQKRKLTIKAARPLLIEEEAGKLVNEDDVRTAAIEACEQHGIVFIDEIDKVAKRGEAGSSGGDVSREGVQRDLLPLVEGSNVSTKYGTVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELTALTKADFVRILTEPKAALIKQYEALLQTEGVALTFASDAVDRLAEIAAQVNERQENIGARRLHTVLERLLDVLSYEAPDRDGQSVTVDAAYVDAQLGELVQDPDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_ECO55
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: CBAR1_DANRE
Sequence: MMSRTPDARARDTQTKQIQENITSVEKHFGDLCQLFAAYVRKTARLRDKADLLVKEINVYADTETPNLKCGLKNFADQLAKVQDYRQAEVERLEVKVIEPLKAYGNIVKTKREDLKQTQSARNREAKQMQQLERMRQRNPSDRQIISQAESELQRATMDATRTTRQLEETIDDFEKQKIRDIKKVLGEFVTVEMAFHAKALEIYTTAYQHIQNVDEEGDLEVFRNSLHPPDYQSRLEIVRANSKLSLNRTGTSMSKSGTMQSRTSSRQRKRDDEEDEEEDDEDEDDLEEVTDDEH
What is the function of this protein?
Acts as a positive regulator of ciliary hedgehog signaling (By similarity).  Plays a role in ciliogenesis (By similarity).  Plays an important role in the mitochondrial function and is essential for maintaining mitochondrial morphology and inner membrane ultrastructure (By similarity).
What are the official names of this protein?
CBY1-interacting BAR domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CIBAR family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PB1F2_I96A2
Sequence: MGQGQGTPWIQSTGHISTQKEEDGQKIPKLEHRNSTRLMGHYQKTMNQVAMPKQIVY
What is the function of this protein?
May play an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm, host cytosol.
Protein: PKPA_PHYB8
Sequence: MPDYEKVIEASGNGRYSKLNTVLGKGAYKVVYKAIDREEAINDNEITNVKVTRQEFKDLGHEIDILKSVRHPNIITFHDAWYNETEFVFITELMTSGTLREYIRKLTPLPNIKIVKRWCRQILKGLAYLHGHEPPIIHRDIKCDNIFINGAHGEIKIGDMGTAEMKNGKKYTVIGTPEFMAPEMYEEQGYNEKVDIYAFGMCLLEMATGEYPYGECTNAVQVFKKVTQTIKPECLSRVQDPELLTLVNICLTPEDERMTAQEILEHRFLAVEPEVVLVSKDMTMKLLTLQVVFKGMDKLSVKFEFNADTDTAADVVAEMIEEQVLQNCYQQLITCEINRILRDIARNQGPPDKGEDEKIVWRRENDIRSELERAKKDLALAVERVFEAEKKCELLEQHNIIAEERCKETIFALEQAKFQIPDLLQPQPQPQPQPQPQPQPQPQFQLQPQLQYLSPQSTTSPGPTSDDNSTNSTMLSSLESELSKLCVSGDEQVETTTHSALMENVLAGKAKYYEYSNDTSIDKFVMDTAGATNRSKDKQKQWAAKLQDQDIMTVGDLRDLHDEDWSGIGLTVFALRALKNMLAGKKAAVTQRGLQGTRSGASTPVEEQEQELM
What is the function of this protein?
Serine/threonine protein kinase that probably participates as an intermediate in an intracellular system controlling nuclear proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase pkpA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: CDD_SHEWM
Sequence: MQDRFIKCIAQLPKPLSDALIPLLNADFAGHIDAQQLGMLTTKSQLEESELLLALLPIAAALAKPPISEFYVGAIAKGKSGDIYMGANLELSGEALFHSVHAEQSAISHAWLSGETQILDVVVNFSPCGHCRQFMNEMVEGQKVVIHLPEQKAQPLAHYLPYAFGPSNLNITEPLLSKQQHELSLDSSDPMIIEALDHASLSYAPYSNSYAAVVLETKDGATYCGRYAENAAFNPSMLPMQMALSTMTRHNREFTEINRAVLIESAQGKISLVGATMDALHAVAAVELEHIVIDPA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: HEM1_LEGPL
Sequence: MVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPEVLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFRASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFDGKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMIEKGMDERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNKLTHNPTIGLRQMAWDNREDLLDLARYLFDTTANQSLYEEIS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PYRC_ANADE
Sequence: MSDVLFIEGGRVIDPAGGVDGVRTVVIRDGKVAEVAERVERPRDARVLDARNRWVTPGFVDLHVHLREPGQEYKETVATGARAAVAGGFTAVCAMPNTKPVNDCAAVTELVLARAAAAGLARVYPVGAISKGSGGEELAEYGELKASGCVALSDDGRPVMSSALMRRALEYARAFGLPLTVHEEDLHLVGKGVMHEGAAATRLGLKGIPSQAEDVMVLRDIALVELTGGRLHVAHVSTAGAVRAIREAKRRGLPVTGEVTPHHLALTDDDVAASGYSTDFKMNPPLRSADDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGIVGLETAFSVCLGLVREGALTERRLVEALTAGPARVFGLPAGTLARGAAADVAVLDAAAEWTLDPARLQSKGRNTPWKGRRLAGRCTHTIVGGRIVHEEGKADR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PSAA_TRICV
Sequence: MAISSTERRAKNVQIFVEKDAVETSFAKWAQPGHFSRTLAKGPKTTTWIWNLHADAHDFDSQTSSLEEVSRKIFSAHFGQLAVIFLWISGMHFHGAYFSNYSAWLSDPISIKQSSQVVWPIVGQEILNADVGGNFQGVQTTSGWFQMWRAEGITSEVELYWIAIGGLIMSALMLFAGWFHYHKAAPKLEWFQNAESMMNHHLAGLLGLGCLSWSGHQIHIALPINKLLDAGVAPQEIPLPHEFLINRELMAQLYPSFNKGLAPFFSGQWGEYSDFLTFKGGLNPVTGGLWLSDIAHHHLALSVLFIFAGHMYRTNWGIGHSMKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYAMPPYPYIATDYATQLSLFTHHMWIGGFCVVGGAAHGAIFMVRDYTPANNYNNLLDRVLRHRDAIISHLNWVCIFLGCHSFGLYIHNDTMRALGRPQDMFSDKAIQLQPIFAQWVQNIHLLAPGTTAPNALATTSYAFGGDVVEVGGKIAMMPIKLGTADFMVHHIHAFTIHVTVLILLKGVLYARSSKLIPDKANLGFRFPCDGPGRGGTCQSSSWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTITPDGNISHITGGNFAQSSITINGWLRDFLWSQASQVIQSYGSASSAYGLIFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLNFAPAIQPRALSITQGRAVGLAHYLLGGIGTTWSFFLARAISIT
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HSLO_EDWI9
Sequence: MPHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLKFDGDITVQLQGDGPLKLAVINGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPKEGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGEQDGQPAAAGMLLQILPTQPNNVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASALMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HVM37_MOUSE
Sequence: EVKLLESGGGLVQPGGSLKLSCAASGFDFSRYWMSWVRQAPGKGLEWIGEINPDSSTINYTPSLKDKFIISRDNAKNTLYLQMSKVRSEDTALYYCARLHYYGYAAYWGQGTLVTVSAE
What are the official names of this protein?
Ig heavy chain V region X44.
Protein: SPC19_CANGA
Sequence: MQSLEQCVNSLEAIVHQLDGSVSRLARNGEASNELCEGILKIKRVFELVPEYDVESARLALFEEVDPMVKTLGDKIEKALIRKRRELENLRQTSELNSLRLSGDLYFSETGIDNQDMDVSTDAIAIASATDAELDELRALKARRAELQELLDGR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit SPC19, Outer kinetochore protein SPC19.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: ANTR5_ARATH
Sequence: MKLSNIPQRYVIVFLTFLSTCVCYIERVGFSIAYTVAADAAGINQSSKGTILSTFFVGYACSQVPGGWAAQKIGGRKVLLLSFVLWSSTCFLVPLDPNRVGLLVVARLLVGVAQGFIFPSIHTVLAQWVPPHERSRLVSITTSGMYLGAALGMWLLPALVELRGPESVFLAEALAGVIWSLLWIRYATDPPRSEHPKAAAAGFGGALLPTNVNHHKVTHIPWKKIMLSLPVWAIVVNNFTFHYALYVLMNWLPTYFELGLQISLQGMDSSKMVPYLNMFVFSIVGGFIADYLITKRILSVTRTRKFLNTVGFLIASAALMVLPMFRTENGVILCSSVALGFLALGRAGFAVNHMDIAPRYAGIVMGVSNTAGTLAGIIGVDLTGKLLEASKLVYSDLSHPESWRVVFFIPGLLCIFSSVVFLLFSTGERIFD
What is the function of this protein?
Inorganic phosphate and probable anion transporter.
What are the official names of this protein?
Probable anion transporter 5, Phosphate transporter PHT4;6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: UFC1_ANOGA
Sequence: MVDDGTRKALSGIPLLKTKAGPRDKELWVQRLKEEYQALIKYVQNNKASDMDWFRLESNKEGTKWFGKCWYMYNLHKYEFDVEFDIPITYPTTSPEIALPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGIAHAMALGLAPWLAVEVPDLIEKGVISYQEKGSS
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: ATPB_SHEPC
Sequence: MSTGTVVQVIGAVVDVEFPQDAVPQVYDALKITGEGACNGLVLEVQQQLGGGVVRTIAMGSSDGLRRGLEVVNSGSPISVPVGTATLGRIMNVLGEPIDEAGPIGEEERYVIHRAAPSYEDQSNTTELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYYEMKDSGVLDKVAMVYGQMNEPPGNRLRVALSGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVANGVQTVLQRYKELKDIIAILGMDELSDDDKTTVFRARKIERFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGILNGEFDHLPEQAFYMVGSIDEVIEKANKKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AP1G1_MOUSE
Sequence: MPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPSEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDITLTGAPAAAPTPASVPQISQPPFLLDGLSSQPLFNDIAPGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSVVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (By similarity).
What are the official names of this protein?
AP-1 complex subunit gamma-1, Adaptor protein complex AP-1 subunit gamma-1, Adaptor-related protein complex 1 subunit gamma-1, Clathrin assembly protein complex 1 gamma-1 large chain, Gamma-adaptin, Gamma1-adaptin, Golgi adaptor HA1/AP1 adaptin subunit gamma-1.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (By similarity). Co-localizes with AFTPH/aftiphilin in the cytoplasm (By similarity).
Protein: K2C3_HUMAN
Sequence: MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRYSR
What are the official names of this protein?
Keratin, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, CK-3, Keratin-3, K3, Type-II keratin Kb3.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: PLSY_HALH5
Sequence: MELGWLLVIGSYLLGSVSFSYIIAKKIKKVDIRQHGSGNAGATNTLRVLGVGPAVTVLLLDILKGVIAVVVTVQLTPDGDGWFAAAAGIAAIIGHNWPIYYGFRGGKGVATTIGVLASLVPLAAVLAGVIAIGSIVWTRYVSLGSLLFVTLTALLVAVLSQWFGYPVAYIYLTIIVAILSMWRHRSNIQRLLSGTENKLGRKKETT
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
Protein: GLRX4_BUCAP
Sequence: MNVIEKIERQIKDNIILIYMKGTPQSPSCGFSAQAVQALSICGEKFAYVDILENLDIRKELPRYANWPTFPQLWIKGELIGGCSIILEMLENGELKKIISNAVLNSK
What is the function of this protein?
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.
What are the official names of this protein?
Glutaredoxin 4, Grx4, Monothiol glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO42_RHIME
Sequence: MRKIIHIDMDAFYASVEQRDNPELRGKPVAVGYPEARGVVAAASYEARKFGVHSAMPSVTAKRKCPELIFVPHRFDVYRAVSRQIQAIFAEYTPLVEPLSLDEAYLDVTENFRGLKLATEIAEEIRGRIRAETHLTASAGVSYNKFLAKMASDQRKPDGLFVITPKHGPDFVQALPVKKFHGVGPATAEKMKRLGIETGADLKSRDLAFLQQHFGKSGPYFYWIARGIDERKVKPDRIRKSIGAEDTFREDVHDLETARAGLKPLIDKVWHYCEASGIRGKTMTLKVKWADFTQITRSKTIVAPIASVAEMSEIAELLLSPIFPAPKGIRLLGVTLSSLDTVDDRSEPQLALAL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
What are the official names of this protein?
DNA polymerase IV 2, Pol IV 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_THET2
Sequence: MERLAPAKVNLGLSVRFRREDGYHELHTLFAPFSLADRLVVEPVSSGLHFQGPYGRENLAYRAASLYLEAAGQPGGVRILLEKRIPEGAGLGGGSSDAAQVLLALQALYPAEVDLFALARTLGADVPFFLLGRGAEARGVGERLKPLALPPVPAVVFFPGLRVPTPLVYRAVRPEDFGPDLPVEAILEALARGEEPPYWNSLEGPAFRLFPELKEVRGRMRALGLRGVLMSGSGSAFFGLAEGPDHARRAAEALRAWGRAWAGTLGGGDAGSGPA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RPOY_STRP4
Sequence: MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVEENRPEYNIEYIELLSDKLLDYEKETGAFEITEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: METK_XYLFM
Sequence: MSSYLFTSESVSEGHPDKVADQISDAVLDAILVQDPRARVACETMVKTGVAIIAGEITTSAWVDLEALTRKVIVDIGYNSSDVGFDGATCGVLNLIGKQSPDINQGVDRKKAEEQGAGDQGLMFGYATNETDSYMPAAIHISHRLVEQQAKIRKKSNSPLPWLRPDAKAQITLRYEDGVASAIDAVVLSTQHDPGIKQKDLVEAVREEILKPVLPSKWLHKGTKFHINPTGKFVIGGPVGDCGLTGRKIIVDTYGGSARHGGGAFSGKDPSKVDRSASYAVRYVAKNVVAAGLADRCEVQVSYAIGVAEPISISVTTFGTGKVPDDKIEKLIRQHFDLRPYGIIKMLDLIHPIYQPSASYGHFGRKPREFAYTNSNGGRVVATAFSWEKIDKAEVLRADAKLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BACVZ
Sequence: MKELEVRTASSAYPVYIGEGIRKQAAALLSSLNRPLTKILLIIDAEVDRLYGDEMFRLLNETWPVKKVIVPSGEEAKSLKEYERIQTEAIAFHMDRSSCMIAFGGGVTGDLAGFCAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHKLGKNLIGAFYQPKAVIYDTELLKTLPEQELRSGMAEVIKHAFIADHAFLEKLLTFDTLQGLTSAELNEMIYKGISIKSAVVREDEKEEGIRAFLNFGHTLGHAVEAEYGYGRITHGDAVALGMQFALYVSEQVARCKMNRKELTQWLIGLGYPGSIRQDIETPVLSARMMNDKKTRGGMTQFIVLKELGEARDCMLSKDELENLLNKWRMEETA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.