PharMolix/UniProtQA huggingface dataset:
Protein: RL36_DINSH
Sequence: MKVKNSLRSLKQRHRDCRVVRRKGRVYVINKTQRRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SHU2_CANGA
Sequence: MNEDASVINYSEIFSTLVKDDGVDDMVASFLYYMFPRELFIRGLSLLESSDMFIYVFDAMKGESSESEVNTDVDTSVNLSSKENIATSTTATQINAKDNSVDVTKNYLNKLYEDDDLLQYRLIVKSSSSDGIETPVYVDLHNWLCSCEEYTEIMRECLLADKDLVQEFVQLIDDFSCFRDDTFGQIEAHSLSLQKYVNTKKLLCPHLLAYSIILLSSPKVLRHYTVEKPGVIVIPITSIDEWLKLHINVLYSEKK
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTC_NEIAN
Sequence: DQGAGVTYLEPTGSQIGHKESIKDTARVLGRMYDGIEYRGFGQEIVEELAQYAGVPVFNGLTNEFHPTQMLADALTMREHSSKPLNEIAFAYVGDARFNMGNSLLLLGAKMGMDVRIGAPKALWPSENIIAQARALAEETGAKVTLTENAEEAVQGVDFIHTDVWVSMGEPKETWEERIALLKSFRVTPELMAASGNPNVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVT
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEMI_MOUSE
Sequence: MNLSMKQKQEGAQENVKNSPVPRRTLKMIQPSADGSLVGRENELPKGLFKRKLWDDQLASQTSSCGPEANENKDVGDLTQEAFDLISKENPSSQYWKEVAEQRRKALYEALKENEKLHKEIEQKDSEIARLRKENKDLAEVAEHVQYMAEVIERLSNEPLDNFESPDSQEFDSEEEAVEYSELEDSGAGTCAEETVSSSTDARPCT
What is the function of this protein?
Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:12192004, PubMed:9635433).  It is degraded during the mitotic phase of the cell cycle.  Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle (PubMed:12192004, PubMed:9635433).  Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (By similarity).  Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (By similarity).
What are the official names of this protein?
Geminin.
What is the protein family that this protein belongs to?
Belongs to the geminin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic but can be relocalized to the nucleus.
Protein: FEN_CALMQ
Sequence: MGVTELGKLIPDNLRRRVSLEQLNGKLIALDAYNALYQFLASIRQPDGTPLMDSQGRVTSHLSGLLYRTINLLEYGIKPVYVFDGKPPELKLIEIEKRRRVREKAVEDWIKAVEEGKKSEARKYAQRALFITSDMVDEAKRLLDSMGVPWVQAPSEGEAQAAYMASKGIVWAAGSQDYDSFLFGAPRLVRNLTISGRRKLPGRDEYVEVTPELIELNDVLKALRLRDRGQLIDLAILLGTDYNPEGIPGIGPQRALRLIQEYGSLDKLMNTVLKNAQFPVDPFKIREFFLNPPVTQEVNVKFKEPNEDEVVRLLVEEHDFSQDRVKNALERLRKSMGKAKGSTTLDSFFG
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: CATR_SPESI
Sequence: LTEEQKQEXREAFDLFDTDGSGTIDAKELKVXMXALGFEPKKEEIQKMISDIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDQTGKITFKNLKRVAKELGENLTDEEIQEMIDEADRDGDGEINEEEFFRIMKKTSLF
What is the function of this protein?
This calcium-binding protein is found in the basal body complexes (the functional homolog of the centrosome in animal cell).  In mitotic cells it is specifically associated with the poles of the mitotic spindles at the sites of the duplicated basal body complexes.
What are the official names of this protein?
Caltractin, Centrin.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
Protein: PR1B6_ARATH
Sequence: MASPLLPTSTTPDQLPGGDPQLLSSLRVLLSRVLATVRHASADARPWAELVDRSAFSRPPSLSEATSRVRKNFSYFRANYITLVAILLAASLLTHPFALFLLASLAASWLFLYFFRPADQPLVIGGRTFSDLETLGILCLSTVVVMFMTSVGSLLMSTLAVGIMGVAIHGAFRAPEDLFLEEQEAIGSGLFAFFNNNASNAAAAAIATSAMSRVRV
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein B6, AtPRA1.B6, Prenylated Rab acceptor 3.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: S1FA_SPIOL
Sequence: MAVNEVEAKGLNPGLIVLLVIGGLLLTFLVGNFILYTYAQKNLPPKKKKPISKKKMKRERLKQGVAPPGE
What is the function of this protein?
DNA-binding protein that specifically recognizes a negative element (S1F) within the RPS1 promoter.
What are the official names of this protein?
DNA-binding protein S1FA.
What is the protein family that this protein belongs to?
Belongs to the S1FA transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDCA5_HUMAN
Sequence: MSGRRTRSGGAAQRSGPRAPSPTKPLRRSQRKSGSELPSILPEIWPKTPSAAAVRKPIVLKRIVAHAVEVPAVQSPRRSPRISFFLEKENEPPGRELTKEDLFKTHSVPATPTSTPVPNPEAESSSKEGELDARDLEMSKKVRRSYSRLETLGSASTSTPGRRSCFGFEGLLGAEDLSGVSPVVCSKLTEVPRVCAKPWAPDMTLPGISPPPEKQKRKKKKMPEILKTELDEWAAAMNAEFEAAEQFDLLVE
What is the function of this protein?
Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin.  May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin.  Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.  Required for efficient DNA double-stranded break repair.
What are the official names of this protein?
Sororin, Cell division cycle-associated protein 5, p35.
What is the protein family that this protein belongs to?
Belongs to the sororin family.
Protein: PDX2_PLAF7
Sequence: MSEITIGVLSLQGDFEPHINHFIKLQIPSLNIIQVRNVHDLGLCDGLVIPGGESTTVRRCCAYENDTLYNALVHFIHVLKKPIWGTCAGCILLSKNVENIKLYSNFGNKFSFGGLDITICRNFYGSQNDSFICSLNIISDSSAFKKDLTAACIRAPYIREILSDEVKVLATFSHESYGPNIIAAVEQNNCLGTVFHPELLPHTAFQQYFYEKVKNYKYS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of Pdx1.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PDX2, PfPDX2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRBR1_HUMAN
Sequence: MSNQVLCCVVLCLLGANTVDGGITQSPKYLFRKEGQNVTLSCEQNLNHDAMYWYRQDPGQGLRLIYYSQIVNDFQKGDIAEGYSVSREKKESFPLTVTSAQKNPTAFYLCASSIRSSYEQYFGPGTRLTVTEDLKNVFPPKVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSESYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDSRG
What is the function of this protein?
The beta chain of TRAV27*01J42*01C*01/TRBV19*01J2S7*01C*02 alpha-beta T cell receptor (TR) clonotype that is specific for HLA-A*02:01-restricted M/matrix protein 1 immunodominant epitope GILGFVFTL of influenza A virus (IAV).  Classified as a public TCR clonotype, it is preferentially selected in effector memory CD8-positive T cells among multiple HLA-A*02:01 carriers/individuals and confers long-lived immunity against IAV infection.  Can cross-recognize sporadically emerging IAV variants by molecular mimicry, inducing immunity toward different influenza strains (PubMed:1833769, PubMed:7807026, PubMed:29997621, PubMed:27036003, PubMed:12796775, PubMed:18275829).  Antigen recognition initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell differentiation into effector/memory T cells (By similarity).
What are the official names of this protein?
M1-specific T cell receptor beta chain, TR beta chain TRBV19*01J2S7*01C*02.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RPIA_STRPD
Sequence: MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLEAPKAS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: DNAK_SALTI
Sequence: MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAWLDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDINDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YCF3_ILLOL
Sequence: MSRSRINGNFIDKTSSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEATRPEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWSDQAAEYWKQAIALTPGNYIEAQNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ENGB_ZYMMO
Sequence: MSPENDIRLEAGRKLFAGAVNFLKSAPALEFLPAPTAPEVAFAGRSNVGKSSLINALTNRNSLARASTTPGRTQELNFFDVGEPLQMRLVDMPGYGFAKAPKDVVKRWKWLINDYLRGRAVLRRSLILIDSRHGIKDVDRDLMKMLDDAAISYRVVLTKSDKIKAVELEKTVKAITEEMRKHPAAFPEIIATSSEKGTGIAELRAAVYDAII
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
GTP-binding protein EngB, GTP-binding protein CgpA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYP_PELTS
Sequence: MRASELFSPTLREVPAEAEVVSHQLLLRAGFIRRAAAGVYTYLPLAMRVIKKIEQIVREEMDRQGGQELLMPIIQPAEIWQESGRWDVYGPELFRLKDRHDRDFALGPTHEEIITVLVRGEVSSYKQLPLLLYQIQNKYRDERRPRFGLMRGREFIMKDLYSFDRDEEGLNVSYMKMYEAYTRVFQRCGLHFRPVEADSGAIGGSDTHEFMVLAESGEATVLYCDGNGCDYAANVEKAALPFKERRTEEEMRPVAARETPGCRSVEEVCGFLGVPARKIIKTLIYRTEKEVLAALVRGDRDVNEVKLLNASGALRLELAGADTVKSITGASVGYAGPVGLKGVRIIADPEAAAAVNAVTGANRDDTHLINVNPGRDFKIDLVADIRMVQAGEPCPRCGAGLKEAKGIEVGQIFKLGDKYSRALGASYLDEKGQSRPVIMGCYGIGITRTMAAAIEQNHDRDGIIWPASIAPFHVVVIPVNVKDGGQYAMAEEVYSRLWAAGIEAVLDDRTERAGVKFKDADLIGYPLRITIGAKAVEEKLVEIRIRKNGETVFVPMNELEEKVEDMLKEL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXM13_MACGS
Sequence: MKLTLFILIVFVVLANVYAAGISERNIIGGRVIKLCGGGAQKCCDREPRCDPCRKCVQSFHSGVYMCSDKKSNCS
What is the function of this protein?
No toxicity is observed upon intracranial injection into mice and intrathorax injection into crickets.
What are the official names of this protein?
U14-hexatoxin-Mg1a, U14-HXTX-Mg1a, Neurotoxin magi-13.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMG_PSEPF
Sequence: MDFPSRFEVIVIGGGHAGTEAALASARMGAKTLLLTHNVETLGAMSCNPAIGGIGKSHLVKEIDALGGAMAMATDLGGIQFRVLNSRKGPAVRATRAQADRILYKAAVREILENQPNLWIFQQAADDLIVEQEQVRGVVTQMGLRFFADSVVLTTGTFLGGLIHIGLQNFSGGRAGDPPSIALAHRLRELPLRVGRLKTGTPPRIDGKSVDFSVMTEQPGDTPIPVMSFMGNKEQHPRQVSCWITHTNARTHEIIAANLDRSPMYSAAGEIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIVQSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGANAALRAKGKEAWCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCKKRESIELEEQRLKSTWVRPGTQQGDAIAEKFGTPLTHEYNLLNLLSRPEIDYAGLVEVTGLGAEDPQVAEQVEIKTKYAGYIDRQQDEIARLRASEDTKLPVDIDYTNISGLSKEIQSKLGATRPETLGQASRIPGVTPAAISLLMIHLKKRGAGRQLEQSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHH_RHOCB
Sequence: MSGTMPLPPHRPGGYNVVIITLDQHAAGPAARALPRLQHDFPDIHVSVHAAAEWSENPAKLAAAKAAVLGANIVVANLLFIDEHLQAILPEMTAVRDNLDAFVGMVADPQIVRLTKMGDLDMTKPASGPMALLKKLRGKSEPGAGSAEKQMSMLRTIPKMLKFIPGKAQDLRAWFLCMQYWLGGSEDNIESMVRYLVGRYADNRDWRGIKAAAPIDYPEVGLYHPDMPGRITTDPAKLPQPANPVATIGILMLRSYILAKDTAHYDAVIRELQAHGVAVLPAFAGGLDGRPAIEEFLHGKIDTLLSLSGFSLVGGPAYNDSDAAVETLKALDVPYVTAQPLEFQTLGQWRASGGGLGPVETTMLIALPEIDGATNPTVFAGRHDPAGCLTCARGCKPDPEAESHAMAPCPERIETLVDKVVRMAKLRRSKVAERKVGIVLYGFPPNAGAAGTAAYLSVFESLFNVMHAMKASGYQMGELPESVQELRDAVLCGPNTTHGQPAQIAARIPAAEFVARTKWLKDIEAAWGSTPGKHQTDGRDVFVLGRQFGNVFVGLQPVFGYEGDPMRLLFEKGFAPTHAFAAFYRWLREDFAADTLLHFGMHGALEFMPGKQAGMCESCWPDRLIGNLPNVYLYAANNPSEATLAKRRSNAVIVSHLTPPLAQSGLYKGLAEIKESLGRLRALPPDSPEREDLEALVREQAKGVNMDASDLSTLWEKLLETEGALITEGLHVVGRPMTAEARAEMLALMPENADRARADKLLQEEHEIAGLLHALDGRYVPPVPGGDLVRSPEILPTGRNIHAFDPFRMPTAFAIKDGAAQAARLLATHPTLPRSIALVLWGSDNIKSDGGPIGQALALMGARPRFDNYGRLAGAELIPLSELGRPRIDVVMTLSGIFRDLLPLQTKLLAEAAYLCASAENEPLAQNFIRANVLATMQDTGMDFETASLRVFSNAEGAYGSNVNTLVGSAGFGDEDELADAYEARKSFAYGRDGKSTKQVNLLQNVLSKVDLAYQNLESVELGVTTVDHYFDTLGGIARATKRAQGGKETPVYIGDQTRGAGTVRTLQDQIALETRARSLNPKFYEGLLKHGAEGVRQIEAQVTNTLGWSATTGQVEPWVYQRLSETFVLDDEMRERLASLNSAASSRMAQRLLEASDRNYWQPDPATLAALQAAADELEDRMEGVAAE
What is the function of this protein?
Involved in bacteriochlorophyll pigment biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoroporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase subunit H, Mg-protoporphyrin IX chelatase subunit H.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunit H family.
Protein: HIS4_BAUCH
Sequence: MIIPALDLINSTVVRLHQGNYQQQRCYSDDPLYYLHNYLRQGAEMLHLVDLTGARDPSARQIKLLTSLLASVKGRTLVQVGGGIRNAADIEVMLQAGAHRVVIGSTAVKKPLEVQQWFKRFGPEALVLALDIRIDTNGKHWVAVSGWMENSGVLLEQVIDQYTQQVELKNILCTDISRDGTLSGMNIELYRLLCGNWPSIAFQSSGGIGSLTDIIKLRNIGVKGVIIGRALLEEKFTLAEAIACWQKE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COP4_COPC7
Sequence: MRPTARQFTLPDLFSICPLQDATNPWYKQAAAESRAWINSYNIFTDRKRAFFIQGSNELLCSHVYAYAGYEQFRTCCDFVNLLFVVDEISDDQNGQDARATGRIFVNAMRDAHWDDGSILAKITHEFRERFVRLAGPKTVRRFADLCESYTDCVAREAELRERNQVLGLNDFIALRRQNSAVLLCYSLVEYILGIDLDDEVYEDPTFAKAYWAACDFVCWANDVYSYDMEQAKGHTGNNVVTVLMKEKDLSLQEASDYIGRECEKQMRDYLEAKSQLLQSTDLPQEAVRYIEALGYWMVGNLVWSFESQRYFGAQHERVKATHVVHLRPSSVLEASCDSDSDSDC
What is the function of this protein?
Sesquiterpene synthase that catalyzes the cyclization of farnesyl diphosphate (FPP) into multiple products, including germacrene D, beta-copaene, beta-cubebene, (+)-sativene and cubebol, a natural sesquiterpene alcohol used in the food industry for its cooling and refreshing taste.  Terpenoid hydrocarbons resulting from cyclization of farnesyl diphosphate are intermediates in the biosynthesis of biologically active compounds such as antibiotics, toxins and pheromones.
What are the official names of this protein?
Linoleate 10R-lipoxygenase COP4, (+)-sativene synthase, Beta-copaene synthase, Beta-cubebene synthase, Sesquiterpene synthase COP4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: FABG_VIBHA
Sequence: MNLEGKIALVTGASRGIGRAIAELLVERGATVIGTATSEGGAAAISEYLGENGKGLALNVTDVESIEATLKTINDECGAIDILVNNAGITRDNLLMRMKDDEWNDIINTNLTPIYRMSKAVLRGMMKKRAGRIINVGSVVGTMGNAGQTNYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIETDMTKALNDDQRAATLSNVPAGRLGDPREIASAVVFLASPEAAYITGETLHVNGGMYMV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LPXK_NEIMB
Sequence: MPNCFKFHTVIERHWQKPYPVLSFLLKPLSGLFAKIAAKRRTDFLSGKRQSEKLPVPVVVVGNIHAGGTGKTPIVAALVSGLQEKGVKVGIISRGYGRKSKAVHVLNAESRAEDAGDEPLLLFRKTGAPTAVGSSRAEAGRALLAAHPDIGLIVADDGLQHYALRRDVEIAVFPAADTGRTDLDLLPNGSLREPLLRLDSVDAVVVSGGKADALFRPSENMFHSRIEAGRIYRLNNPSEILDTGRLKNQTVVAVAGIAKPARFFDSLRNMGITVKRTVALPDHADISAADLPDADAVIITEKDAVKFSDGICTDNVWVLPVCAIIEPDLAAFVLERLEDVPKAV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RUVB_PROMP
Sequence: MAIISSSLDESNIPRSRKELRLVDSKIIAEEKINKNLNLARPNSFKEFIGQEQIKSSLKIAIEASKYRKEALEHTLLYGQPGLGKTTLALLISYEMNTKCKVASAPSLERPRDIVGLLLGLKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANRGTRCRTINLPKFTLIGATTKLASISAPLRDRFGLCHKIELYSNDELHQIIFNFATLINLQLENDACSALAKISRGTPRIALRLLKRVRDYAQVIKNTNKISLEIIEKALNSQKIDNKGLDNIDRKFLSFLNLNNNHPIGLDSIAAGLGEESSMLEFVVEPYLIQIGFIMRTPRGRKLTSLGKKYISSRNEKY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ORF5_SPV1C
Sequence: MVKMINLLVVENNNSNWDKIFSFVFDIFLFIFDVIWNTKLPMTNTSIAYFLVFFMVIKLSIYAIHGTSTQYNNLGSTVNNGVSQVYSSTVRKGINVGKNVYQNSNKQQVKKELKRQSIRYQAKNIRSTKFKGDKK
What are the official names of this protein?
Uncharacterized protein ORF5.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF5 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PYRR_STAHJ
Sequence: MSERIIMDEAAIQRTVTRMAHEILEYNKGTENLVLLGIKTRGEFLAIRIQDKINQIEQKIVPTGTIDITHFRDDIEIANKQITQDAIEIDADINDKVVIIIDDVLYTGRTVRASLDAILLHSRPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEESVLVYLNEKDSQNAVIIE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RL14_YERPG
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGIGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.