PharMolix/UniProtQA huggingface dataset:
Protein: CYB_VOAGY
Sequence: MTNIRKTHPLLKIINHSFIDLPAPSNISSWWNFGSLLGICLMLQIITGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGMYYGSYMSIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIVALVMVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDILGIFLLLLFLMSLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALLPHLHTSKQQSLMFRPLTQTLYWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFVTILILMPMAGMIEDNILKMT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: C99L2_HUMAN
Sequence: MVAWRSAFLVCLAFSLATLVQRGSGDFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVCEEPQVKYSTLHTQSAEPPPPPEPARI
What is the function of this protein?
Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane.  Acts at the same site as, but independently of, PECAM1 (By similarity).  Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity).
What are the official names of this protein?
CD99 antigen-like protein 2, MIC2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD99 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side. Cell junction.
Protein: ULAG_ECO27
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGANVCVDFWCGTGKQSHGNPFMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGTLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAME_XANCP
Sequence: MRNLLLVAAVALSTAGCGIIYKQPIYQGNLIKQTAVEQLQVGQSKQQVSALLGTPSIPDPFHAQRWDYTSTQRVDRLARTDVKNFTVFFENEQVVRWEGDYFPAQDEQLAKSAPKQFGRNLARDKKKQRGR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NUOM_RICBR
Sequence: MLELPIISITIFLPLISVLYILLFISQSKKPDKQIHTMYVAVLSSVLTFISTIYILIEFDSSNPTYQFVERYSWLDKIGLEFHVGIDGISIFFVSLTSFLTLICIIGSLFTVKKYIKEYLVCFLLMESFCIGAFTSINLLVFYLFFEVILVPMYIIIGVWGGENRIYAAVKFFLYTFFGSVFFLLSIIYIYSKIHSFDLSNIGEFTNNFPLHVQQILWWAIFIAFAIKIPMIPFHTWLPDAHVQAPTSGSVILAGILLKLGGYGFLRVLLPLLPNASQEFAIYVIWLSVIAIIYASLVALAQKDMKKMIAYSSITHMGYVTIGIFSFTDSGVSGALFQMLSHGIISSCLFLIVGTLYERLHTKEIAKYGGVASKMPVLATFFMIAMLGSVGLPGTSGFIGEFLSLLGIYKVNVIATFLAALGIILGAIYMLKLYKEVMLGEITNKEIINFRDLYIYEIISIAPLILLIIYFGLMPSSILNVFHLSVENLLVKFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit M, NADH dehydrogenase I subunit M, NDH-1 subunit M.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LFTY2_HUMAN
Sequence: MWPLWLCWALWVLPLAGPGAALTEEQLLGSLLRQLQLSEVPVLDRADMEKLVIPAHVRAQYVVLLRRSHGDRSRGKRFSQSFREVAGRFLASEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSAQARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLRDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMKWAKNWVLEPPGFLAYECVGTCQQPPEALAFNWPFLGPRQCIASETASLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP
What is the function of this protein?
Required for left-right (L-R) asymmetry determination of organ systems in mammals.  May play a role in endometrial bleeding.
What are the official names of this protein?
Left-right determination factor 2, Endometrial bleeding-associated factor, Left-right determination factor A, Protein lefty-2, Protein lefty-A, Transforming growth factor beta-4, TGF-beta-4.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_SYNR3
Sequence: MPAQRLDGRQLAAQLEEVMAAAIASGLPRAGRPPGLAVLRVGDDPASGVYVANKEKACARVGLVSHGAHLDAATPQAEIEAKLRQLNQDPAVDGILVQLPVPAGLDDRALLLELDPAKDADGLHPLNLGRLLRGEPGPRSCTPAGVMALLRSNGIDPAGKRAVVIGRSILVGQPMALMLQAANATVTVVHSRTADLAAHTREAEILVVAAGKPGMIGADHVRPGAAVVDVGIHRKPEGGLCGDVRSAEVEPIASALSPVPGGVGPMTVTMLLLNTVRAWSQRFDLPDPTPGY
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YVCA_BACSU
Sequence: MKKIIFICFSLLLALTGGCSMNDNDKNSTNDNKTEAVKPKDMDPKDLPQVPAFQDEKTREYMVSTKEEEPGYYLLESKLKGFRMLFPEDGKYLSRRSSLTGKNKESIGFNSYDKDTNVMFDGHVTYYKEESFANEPKTMLDIVSGKNDYKGEYKKSSKKKTDIYTAKKKDIFDDIDRKYNYSYSYFGYVKSTEEDNLGVEYAFTLGCKNENQPCSLDEEKAKNKVEKLINSITFLIDKKEK
What is the function of this protein?
Required for complex colony architecture.
What are the official names of this protein?
Putative lipoprotein YvcA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PSBY_PROMM
Sequence: MILIVLLPILLAATWAFINIRGAALKQQGLGLVSKNKG
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MVP1_SCHPO
Sequence: MGDNVFLEPDPWASSSNWGSPVKPLNYKTAIGNSSIPLQYRNYWDVFQANNVLLFPEEESYSDIFHVPQDVMKEFFTLIESSSNQPLRQIQFFVLLALVACYQLGVPSTLEQIFKQRNVLPILQRFNPELFNRSSDNETPLFPNNSPPASTTALNLSSNIVPSINESKILEQEDDDVSNKSLPHAQQSIIRSFPDIQKQPKGFFSYPSSTVSSIAPSTLEAGNLHSQQPPKFSVDSSVDDNAITPRKPFSKIPNRLSPSTQPLLSNSRHSSFRLASSSTSFPASLEMNVDIDLEPSGYFFYRHNNYIISDSSNTREVLRRYSDFFWLHSYLMKKYPFRRVPLIPLKKFHSKCFNSKQFFRTPPPGLSDFVNDLSHHPIFSNDEVVRVFFTEPNVFKNWRRENQKRIDQEIEQFLVVPQSQVPDASETVKERLLKLNMSTTTAINNQLNIFRIFEKMIFTLQHFHEDFLRLQNSFNCLLDSGLYHQVFTSTFAQNESKIMSMASGHFYNIDSLLHQQNDAVKHTFLLGLSKEIKILISLRLLIERISEVFSTDLTKVRHTISNDENLLRETANSDESGRNRTFLNRSSKKRAENSLKSKKELYLKNLNQRYQIAHELEQELSYLQDYVFSLGNPYVEYCKQHVKLEEESLKIWHTLESDFSRLET
What is the function of this protein?
Required for vacuolar protein sorting.
What are the official names of this protein?
Sorting nexin mvp1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GSA_SALNS
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSEEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS22_PHYTB
Sequence: ALWKDILKNVGKAAGKAVLNTVTDMVNE
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-2.2TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_ACTSZ
Sequence: MFRGASAINLDAKGRLAIPTRYRPEILEQNQGQLVCTVDIRQPCLLLYPLSEWEMIEQKLLSLANFDPALRSLQRVMLGYATECALDGAGRILLSEPLRQRAKLEKNIMLVGQLNKFEIWSESEWNAQIEQDMVLGSSSEFALSDALKTLSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: QUEC_MYXXD
Sequence: MVKRAVVLISGGLDSTTCLAMAKAKGFEPVCLAVAYGQRHAVELEQARKVAAAMGVTDFRVVSIDLRQVGGSALTADIEVPKDRPSDEMSHGIPVTYVPARNALFLSLALGLAEVVGSTDIYIGVNAVDYSGYPDCRPEFIRSFESMANLATKAGVEGAHFTVHAPLSGLTKADIIREGVKLGVDYGLTHSCYDPDAQGRACGRCDSCVLRKKGFEEAGVPDPTRYTESA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RPAB1_CAEEL
Sequence: MADDELETYRLWRIRKTVLQMVHDRGYLVAQDELDQPLETFKVQYGDRPSEKKPARSDLTILVAHNDDPADQMFVFFPEDAKIGIKTIKAICQQMQEQNISRAIIVVQTGMTPSAKQSIGDMAPKYMLEHFLEAELMVNITEHELVPEHVVMTAEEKAELLARYKLKDSQLPRIQQCDPVARYFGLRRGQVVKIIRPSETAGRYITYRLVV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1, RPB5 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRXN1_MOUSE
Sequence: MGLRAGGALRRAGAGPGAPEGQGPGGAQGGSIHSGCIATVHNVPIAVLIRPLPSVLDPAKVQSLVDTILADPDSVPPIDVLWIKGAQGGDYYYSFGGCHRYAAYQQLQRETIPAKLVRSTLSDLRMYLGASTPDLQ
What is the function of this protein?
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4.  Does not act on PRDX5 or PRDX6.  May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
What are the official names of this protein?
Sulfiredoxin-1, Neoplastic progression protein 3.
What is the protein family that this protein belongs to?
Belongs to the sulfiredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_PSEA6
Sequence: MAAEQLNGYVLHRRAYRETSFLVNIFTLENGKVSAVVKGVRGSKSDKKSLLQPFQPLLIGVSGRSELKNLQQVESTGAMIRLAGQALYCALYLNEVLNRVLADEIPHPEIFVLYQQSMHALVAQTNFEPVLRSFELGLLDALGYGIDLTHDADTGQPVADNGYYRIVPELGCVYQGDIRLSGCYSGQSLLNVASENWDKDSLLAAKHITRTTLGELLGSKPLMSRELFKQTHFKSRGREL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL18_PROM0
Sequence: MTKLSRKLQTQKRHRRLRRFLIGDATRPRLSVFRSNNHIYAQVIDDSAQTTICSASTVDKELREKSEKLPSDCNSSSIVGKLLAKRAIKKGIKQVIFDRGGNLYHGRVKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DCUP_SHEDO
Sequence: MAELKNDRYLRALLKQPVDATPVWMMRQAGRYLPEYKATRAQAGDFMSLCRNAELACEVTLQPLRRYKLDAAILFSDILTVPDAMGLGLYFEEGEGPRFERPTDTVDAIKKLCIPDPEDELGYVMRAVSTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKTFEKIKKMAYAEPAALHMLLDKLADSVILYLNAQVANGAQSLMIFDSWGGALSHHAYREFSLRYMQKIVDGLTRFADGRQVPVTLFTKGGGLWLESMAETGCDALGLDWTVDIGDARRRVGDKVALQGNMDPSMLYASPERIHQEVGQILSSYGKGTGHVFNLGHGIHQHVDPEHAGAFINSVHELSPQYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_EXSCR
Sequence: MSRYRGPRVRIIRRLGTLPGLTNKTSQLKSSSINQSISNKKISQYRIRLEEKQKLRFHYGITERQLLNYVRIARKAKGSTGEVLLQLLEMRSDNVIFRLGMAPTIPGARQLVNHRHILVNDCIVDIPSYRCKPQDFITIKNQRKSETMISKNIELYQKSKIPNHLTYSSLEKKGLVNQILDRESIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PPNP_ECOUT
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: GP7D_CHLPS
Sequence: MSGLSHHHKSRLFLTVLEAANVWLATLSPITRKNYASGIKFLVANHILDGSMKLEGLVCCDHCDILNRIKSLTFTYSGKPVSEASKQARAACYISFTKFLYRLTKGVIKHASPSKDFGNPTFYKIRDKVKTEFISKREWLLFFDALKKISFRDYLIGKLIIQGVRKLTEVISLRTEDISFAKNQVTFKVKKRQNRYQEVKVSYPNFLMQELQDYLGNREGWVFVSGEGQQVAINQVYYYFKLAEGDINSPIKVTPHVLRASALAYLKKMGFADQEIMRVSCLSSTQMLSAYDTGMTDNLTSQLPLIF
What are the official names of this protein?
Virulence plasmid integrase pGP7-D.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: SURF4_HUMAN
Sequence: MGQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCVLVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPTMRESSPKQYMQLGGRVLLVLMFMTLLHFDASFFSIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFLKYDFFQTMSVIGGLLLVVALGPGGVSMDEKKKEW
What is the function of this protein?
Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion (PubMed:30251625, PubMed:29643117, PubMed:33186557).  Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (PubMed:29643117, PubMed:33186557).  Synergizes with the GTPase SAR1B to mediate transport of circulating lipoproteins (PubMed:33186557).  Promotes the secretion of PCSK9 (PubMed:30251625).  Also mediates the efficient secretion of erythropoietin (EPO) (PubMed:32989016).  May also play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi (PubMed:18287528).
What are the official names of this protein?
Surfeit locus protein 4.
What is the protein family that this protein belongs to?
Belongs to the SURF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi- pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: BTUD_VIBCH
Sequence: MIRVNSLQVDSRLLPLSLQANAGEVWHVIGPNGCGKSTLLAALAGMIPFSGSVQVDGLDVSQASLSELARHRAYLAQNNKPSFQLHVFQYLALSVPANVALECSEVASEIDQISRLLNIDDKLHRSIHQLSGGEWQRVRLAGSCLQVSPVLNPSARLLIWDEPAAPLDIAQESLLYRLIERMAGQGLTVIMANHDLNRTLRHADQVLLLSRGVLYRAGSAKEVLTQEVLQSVFGTSIRRVELEGHPHLLFD
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GRH1_ARATH
Sequence: MGLRFPPKVLEHILSFIDSNEDRNSVSLVCKSWFETERKTRKRVFVGNCYAVSPAAVTRRFPEMRSLTLKGKPHFADYNLVPDGWGGYAWPWIEAMAAKSSSLEEIRMKRMVVTDECLEKIAASFKDFKVLVLTSCEGFSTDGIAAIAATCRNLRVLELRECIVEDLGGDWLSYFPESSTSLVSLDFSCLDSEVKISDLERLVSRSPNLKSLKLNPAVTLDGLVSLLRCAPQLTELGTGSFAAQLKPEAFSKLSEAFSNCKQLQSLSGLWDVLPEYLPALYSVCPGLTSLNLSYATVRMPDLVELLRRCSKLQKLWVMDLIEDKGLEAVASYCKELRELRVFPSEPDLDATNIPLTEQGLVFVSKGCRKLESVLYFCVQFTNAALFTIARKRPNLKCFRLCVIEPFAPDYKTNEPLDKGFKAIAEGCRDLRRLSVSGLLSDKAFKYIGKHAKKVRMLSIAFAGDSDLMLHHLLSGCESLKKLEIRDCPFGDTALLEHAAKLETMRSLWMSSCFVSFGACKLLSQKMPRLNVEVIDEHPPESRPESSPVERIYIYRTVAGPRMDTPEFVWTIHKNPENGVSHLAIK
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription.  Involved in embryogenesis regulation by auxin.  Confers sensitivity to the virulent bacterial pathogen P. syringae.  Mediates glucose repression in yeast.
What are the official names of this protein?
GRR1-like protein 1, Protein AUXIN SIGNALING F-BOX 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: H4_ASEAQ
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TMCAL_STRS7
Sequence: MTVTGIIAEFNPFHYGHQYLLSQARGLKIVAMSGNFVQRGEPALVDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLFDYQKLSRLYSEQAEHMTAYLAALPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYVKASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRAPQVTWEHYFPLLKYHILTSPDLTEFFQVNDELASRISAAIRSIATVDELVEAVATKHYTKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQLTQRADTVYQLGHMDMPEQTWGRVPIRPGAMN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THYX_PSELT
Sequence: MTIEVLDRGFVKLLDHMGDDFSAVKAARISHGRDLIDEERDRKLIEYLLRSGHESPFEHIVFTFHIKCPIFVARQWMRHRIASYNELSGRYTELAEEFYLPDLYKRYGERLNENDLQKASKLIEESYKKSHEAYKCLIDMKIPKELARVVLPFATYTQFIWSVNARSLMNFLSLRADSHSQWEMQQFALAVAQVFKSICPWTYESFIRYRYEGDLLKGVNP
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.