PharMolix/UniProtQA huggingface dataset:
Protein: DNAE2_RHOP5
Sequence: MTAPRYAEIGVTSNFSFLEGGSHPQEFVQQASALGLAAIGIADRNTLAGVVRAYSELDNEELFYKPKLLIGARLCFADGTPDILAYPTDRAAYGRLCRLLSAGKLRAGKGECHLSFADLEAFTKTSTPSWPGLSRPSTSSSKAVQVSVDARVKPGHDEAKRAAGESRLLLVLMPPYRFQSHEITAALTRLTALQGAGVWLALVPYYRGDDKRRLARLQRIAAAARVPGIASNDVLYHHESRRALQDVLTCVRDKTTIDKAGRLLESNAERYLKPTEEMARLFRADPDAIAETLRFADRISFTLDELKYQYPDEPVPPGKTAQQHLKDLTEQGIAEYFPNGIDAKLRATIDKELTIIAHRQYAPYFLTVHDIVRYARSQNILCQGRGSAANSAVCYVLGITCVDPTEIDLLFERFVSEERDEPPDIDVDFEHSRREEVMQYIYRRYGRHRAAIVSTVIHYRPRSAIRDVGKALGLSEDVTAALADTVWGSWGKGLNEMQVRQAGLDPTNPMIVRAIDLATELIGFPRHLSQHVGGYVLTQDRLDEFVPIGNAAMEERTFIEWDKDDIDAVKMMKVDVLALGMLTCIRKGFDLIAQHKGKRYELADIKSEDDNEVYKMLQRGESVGVFQVESRAQMNMLPRLRPRCFYDLVIEVAIVRPGPIQGDMVHPYLRRRNGQEPVVYPSPAGHAGEANELKTILGKTLGVPLFQEQAMRIAIEAAHFTPDEANQLRRAMATFRNVGTIGKFEAKMTGNLVARGYDPVFAQNCFEQIKGFGSYGFPESHAASFAKLVYVSAWLKHAHPDAFCCALLNSQPMGFYAPAQIVGDARQNGVEIRGVDVAYSFSQNTLEERCGQHHAVRLGFRQIDGFRWADFDEANLWQARGDAPPEDWGARIVEAREKSPFTSLEQFARATALPKRALILLADADAFRSLKLDRRAALWAVRRLPDDVPLPLFEVAKAREQQDENAAPLPLMPLAEHVVADYQTVRLSLKGHPMQFLRALFAAEGVNTCRAVSETRRNGRRARCAGVVLVRQRPGSAKGVVFITLEDETGIANLVVWPAVMEKFRKEVMGARLLWVEGKIQASPEGVVHLVAEELVDRSAEMARLSDELIAPSASTEREAPLNDDRRDHPDLPAQQIRHPRNVRILPPSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALT_ECOUT
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: THIO_EMENI
Sequence: MGASEHVPPITSKAEFQEKVLNAKGFVVVDCFATWCGPCKAIAPTVEKFAQTYTDASFYQIDVDELSEVAAELGIRAMPTFLLFKDGQKVSDVVGANPGALEAGIKALLA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: IL5_MERUN
Sequence: MRLPLQLSILTLAWVWAVALEIPMSAVVKETLIQLSTHRALLTSNETVRLPVPTHKNHQLCIGEIFQGLDILKNQTARGGAVETLFQNLSLIKKYIDRQKEKCGEERRRARQFLDYLQEFLGVMSTEWTMEG
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils.  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SODC_RAT
Sequence: MAMKAVCVLKGDGPVQGVIHFEQKASGEPVVVSGQITGLTEGEHGFHVHQYGDNTQGCTTAGPHFNPHSKKHGGPADEERHVGDLGNVAAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMM_BURA4
Sequence: MSGHDSGNAKRGRASFGAFVRKPVERDVVASAGEAAEQGSLEAVQAWPDDAVEVGAVVDAYGLKGWIKVATHADAGRGGDALLDARRWWLERGGERLSARILQSKTHGDTVVAHAAGVSDRDAALALRGFRVFVRREDFPELAADEFYWVDLIGLEVVNEQSVALGTVSGMIDNGVHSIMRVEYPAVGKDGQPTTDERLIPFVGVYVKTVDQAARRIVVDWEADY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_YERPP
Sequence: MPHLAELVAKAKAAVEGAQDIAALDLVRVEYLGKKGHLTLQMTSLRELPAEERPAAGAVINQAKQEVQEALNARKEKLESAVLNARLAAETIDVSLPGRRMENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMQEQQPPIRIIVPGRVYRNDYDQTHTPMFHQMEGLIVDRDISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CU1B_HOMAM
Sequence: DRDAQTLTDERSDQGDGNFRYEFETSNGIYTQKTGTPGSEGQSNHQGSFRFTLEDGTIAEVTYIADEYGYQPSSDLLPVPPPAPPHVQRLLEIAAEQRAQGITFD
What are the official names of this protein?
Cuticle protein AMP1B, HA-AMP1B.
Protein: HBB2_TRENE
Sequence: MVEWTDKERTIISDIFSHMDYDDIGPKALSRCLIVYPWTQRHFSGFGNLYNAEAIIGNANVAAHGIKVLHGLDRGMKNMDNIADAYTDLSTLHSEKLHVDPDNFKLLSDCITIVLAAKMGHAFTAETQGAFQKFLAAVVSALGKQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PSAA_ACAM1
Sequence: MTTSPGGPETKGRTAEVDINPVSASLEVAGKPGHFNKSLSKGPQTTTWIWNLHALAHDFDTQTNDLEEISRKIFSAHFGHLSIIFVWISGMIFHAARFSNYYAWLADPLGNKPSAHVVWPIVGQDILNADVGNGFRGVQITSGLFHILRGAGMTDPGELYSAAIGALVAAVVMMYAGYYHYHKKAPKLEWFQNAESTMTHHLIVLLGLGNLAWTGHLIHVSLPVNKLLDSGVAPQDIPIPHEFLFDNGFMADLYPSFAQGLMPYFTLNWGAYSDFLTFKGGLDPTTGGLWMTDIAHHHLALAVMYIIAGHMYRTNWGIGHSMKEIMESHKGPFTGEGHKGLYEVLTTSWHAQLAINLATWGSFSIIVAHHMYAMPPYPYLATDYGTQLNLFVHHMWIGGFLIVGGAAHAAIFMVRDYDPAVNQNNVLDRMLRHRDTIISHLNWVCIFLGFHSFGLYIHNDNMRSLGRPQDMFSDTAIQLQPIFSQWVQNLQANVAGTIRAPLAEGASSLAWGGDPLFVGGKVAMQHVSLGTADFMIHHIHAFQIHVTVLILIKGVLYARSSRLIPDKANLGFRFPCDGPGRGGTCQSSGWDHIFLGLFWMYNCISIVNFHFFWKMQSDVWGAANANGGVNYLTAGNWAQSSITINGWLRDFLWAQSVQVINSYGSALSAYGILFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHSKLKIAPAIQPRAMSITQGRAVGLGHYLLGGIVTSWSFYLARILALG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RLXN_LITCT
Sequence: MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDNPDERDVEVEKRFLGGLIKIVPAMICAVTKKC
What is the function of this protein?
Potent microbicidal activity, active against S. aureus and E. coli.  It acts as well as a membrane-disruptive agent at higher concentrations.
What are the official names of this protein?
Ranalexin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_CUPTR
Sequence: MSVTMREMLEAGCHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFQDAMKYVRQLAANRGTILFVGTKRQSREILAEEAGRAGMPYVDARWLGGMLTNFKTVKTSIKRLKDMEAAKEAGALETMSKKEALMFEREMIKLEKSIGGIKEMGGVPDAIFVVDVGYHKIAVTEANKLGIPVIGVVDTNHSPEGIDYVIPGNDDSSKAVALYVRGVADAILEGRANAVQEVVEAARGDDEFVEVQEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NAPA_SHIF8
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAEMHPILWSRITNSRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVAEYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPSGTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFSRRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFYRQKGLFEEYACFGRGHGHDLAPFDDYHKARVLRWPVVNGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNKLTLDATDPLSKETDFKKCAVKLEKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CEPT1_MOUSE
Sequence: MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKASTAHSNHH
What is the function of this protein?
Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively.  Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface.  Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.
What are the official names of this protein?
Choline/ethanolaminephosphotransferase 1, mCEPT1, 1-alkenyl-2-acylglycerol choline phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: VF423_ASFK5
Sequence: MLWRNEITEFMDQLSKYSQEILKTFKQLRPSEYKQYNEFLTQVTPLLQKTPEKIPEEVDHIFDYLDNVEKICELLVHASSIIISSKIREQVKHGMSFSYKTDLDSLAGILSQKQYVLIHLSKNIAAHYFNTCLNQGKSRLDLKAASVFYNSRPRTASSAELYRKMLYAYGSLQEINYYTEKARNKTLDVEESDSMATIERTARHNLSLMHPLEAMGLTFGATNTDADPEDLKDKTVINLTLPQATESVTYHLNSLMQLKKVSTTSGLNTNILKAFDNIISTPVKKNKMASKLAPGMDVVFTSDNGKTFFTKNVLSKNMLAGPKERVFAYNNLISNLNNSCFIQNHNDFLRQQDSWPFYDAHNFTNKFLMQPIFSGQTRPRLQGAMEAAHVETHLTAFLQSIQPSRPQDPSILASPKLSALILN
What are the official names of this protein?
Uncharacterized protein E423R, pE423R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E423R family.
What are the subcellular locations of this protein?
Virion.
Protein: RS6_HAEIG
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGSVKEAGGQVHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQQVIDELETTFRYNDAVLRSLVIHTKHAVTEASPMKAAKEERKPLAEVENNDFEDAEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SAT7_STACB
Sequence: MSTSTSEPGAIAGLPLGAEVRTDGDATGLSVAIVGGGIVGIALALGLVERGVRVSVYERAQELPEIGVGFAFNGAARKSMARLSPLVMAAVERVANENEQAYDNYWDGYTSTAEDDESSTASKRGKLLFRMPNSNMAWWSCLRSQFLNEMLQALPPGTVTFGKELDSYDDPFDTSDPVRLRFTDGTTAAANVLIGSDGLRSRVRQQLFATSHPEVCNPTYTHKTCYRAVIPMAAAESAMGLSKPHNHCMHTGPRAHVLSYPIAQHKLVNVVLFVTHDEPWVDGTGDEAISVPRMTRPGDKKVLQNRLADWRPEVRNLVAQLPDAPTAWGIFDTAEHPVPFYAAGRVGLVGDAAHASSPHHGAGAGFGVEDALALAVALGMATEKKQSVAAALQAFNDVRYDRTQWLIRSSKETGDIYEWKHFGVGGDPVKIRAELEGRQKTIWDYDVDAMAEEVKTRYEARVTSETTAHQ
What is the function of this protein?
FAD-dependent monooxygenase; part of the satratoxin SC1 cluster involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings (PubMed:25015739).  Satratoxins are suggested to be made by products of multiple gene clusters (SC1, SC2 and SC3) that encode 21 proteins in all, including polyketide synthases, acetyltransferases, and other enzymes expected to modify the trichothecene skeleton (PubMed:25015739).  SC1 encodes 10 proteins, SAT1 to SAT10 (PubMed:25015739).  The largest are SAT8, which encodes a putative polyketide synthase (PKS) with a conventional non-reducing architecture, and SAT10, a putative protein containing four ankyrin repeats and thus may be involved in protein scaffolding (PubMed:25015739).  The putative short-chain reductase SAT3 may assist the PKS in some capacity (PubMed:25015739).  SAT6 contains a secretory lipase domain and acts probably as a trichothecene esterase (PubMed:25015739).  SAT5 encodes a putative acetyltransferase, and so, with SAT6, may affect endogenous protection from toxicity (PubMed:25015739).  The probable transcription factor SAT9 may regulate the expression of the SC1 cluster (PubMed:25015739).  SC2 encodes proteins SAT11 to SAT16, the largest of which encodes the putative reducing PKS SAT13 (PubMed:25015739).  SAT11 is a cytochrome P450 monooxygenase, while SAT14 and SAT16 are probable acetyltransferases (PubMed:25015739).  The SC2 cluster may be regulated by the transcription factor SAT15 (PubMed:25015739).  SC3 is a small cluster that encodes 5 proteins, SAT17 to SAT21 (PubMed:25015739).  SAT21 is a putative MFS-type transporter which may have a role in exporting secondary metabolites (PubMed:25015739).  The four other proteins putatively encoded in SC3 include the taurine hydroxylase-like protein SAT17, the O-methyltransferase SAT18, the acetyltransferase SAT19, and the Cys6-type zinc finger SAT20, the latter being probably involved in regulation of SC3 expression (PubMed:25015739).
What are the official names of this protein?
FAD-dependent monooxygenase SAT7, Satratoxin biosynthesis SC1 cluster protein 7.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IF2P_RAT
Sequence: MGKKQKNKSEDSTKDDTDLGALAAEIEGAGAAKEQEPQKGKGKKKKEKKKQDFDENDILRELEELSLEAQGIGADRDAATVKPTENNEEESASKQDKKKKGQKGKKTSFDENDSEELEDKDSKSKKPARPNSEVLLSGSEDADDPNKLSKKGKKAQKSTKKRDGSEEDEDNSKRSKERSRVNSSGESGGESDEFLQSRKGQKKNQKNKSVPTIDSGNEDDDSSFKIKTVAQKKAEKKERERKKREEEKAKLRKVKEKEELEKGRKEQSKQREPQKRPDEEVLVLRGTPDAGAASEEKGDIAATLEDDNEGDKKKKDKKKKKTEKDDKEKEKKKGPSKSTVKAIQEALAKLREEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEVTLRHLQAQGVEVPSKDSLPKKRPVYEDKKKKKTPQQLESKEALETVEVSAPVEVVDQGVPEKEETPPSVDAEEDEETEDAGLDDWEAMASDEEREKEGNMIHIEVEENPEEEEEEEEDEDEEDSEDEEDEGDSEGSDGDEEDYKLSDEKDLGKAGDTKPNKDASSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHGKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINILKSKKCPFIVALNKIDRLYDWKKSPDSDVAVTLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKDDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKMKILPQYIFNSRDPIVIGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQLIVELKKVFEII
What is the function of this protein?
Plays a role in translation initiation.  Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon.  GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome.  The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.
What are the official names of this protein?
Eukaryotic translation initiation factor 5B, eIF-5B, Annexin V-binding protein ABP-7, Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_LEGPA
Sequence: MKVEIYTDGACKGNPGPGGWGVLLRYNGREKTLHGGEAQTTNNRMELMAAIKGLEALKRPCEVDLYTDSQYLQQGMKEWIKTWKRNGWRNSKKELVKNAELWKSLDNLASIHNIHWHWVKGHSGHLENDLVDALANLGIEELS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_ECOBW
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE2_SALTY
Sequence: MSLLEQLDKNIAASGGLIVSCQPVPGSPLDKPEIVAAMALAAEQAGAVAVRIEGIDNLRMTRSLVSVPIIGIIKRDLDESPVRITPFLDDVDALAQAGAAIIAVDGTARQRPVAVEALLARIHHHHLLAMADCSSVDDGLACQRLGADIIGTTMSGYTTPDTPEEPDLPLVKALHDAGCRVIAEGRYNSPALAAEAIRYGAWAVTVGSAITRLEHICGWYNDALKKAAS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase 2, ManNAc-6-P epimerase 2.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: ATGT_KORCO
Sequence: MGLYFRVRKSDASARLSELKTKSGTLILPEFFPVYNPNKPVITPREMSEMGIKAIITNSYLIYRSPELREAAIERGIHSLLGFDGVVMTDSGAYQIYRYGRVDVTNSEILRFQHSIGSDIGSILDVPMSSEIGREEAESGVERTIRNAEEWASMREELSNTLWVGTPQGSIYRDLVIKCSERIRELDFDYNGVGSIKVALEKYDFVTQVDHFMSIRSILRAGKPFHFWGIGHPSTFAFFAAIGADSFDSASYSLYAEQGRYMTPHGTLLLDEIEEFPCSCPVCSSHDPKEVKAMSKEERTKLLAKHNLYISISEIKKVREAIRGEWLWELVQERSRFHPNLYFALMHLLRRYSSLLEAREPLFKSSGLQCSGPESFLRPEVVRARNRLKYIHYNGKFRRVLYGDVPLGLKYLYPFGQTICPYDEEVQDEPEDDEIITCVLSYQYEFPFPKLPAIMRRSKSTGTLREVSLEGKVIGHFRPNDGAFIPTLDGASLILSHLPYPKGRVVVKGLFSDTVARGTTVFVKFVKEADPSIRPKSEVIVVNESDELLATGKAVLSGVEYHQYHPDHPFIIIRRHVKPRSEEKPPEVDS
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: TKT1_VIBPA
Sequence: MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPANPEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMALAEKALAAQFNKEGHDIIDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHDSDAINAAIEAAKADPRPTLICTKTIIGFGSPNKSGSHDCHGAPLGAEEIAAAREFLGWEHPAFEIPADVYAEWDAKAAGAEKEAAWNAKFEAYAAAYPTEAAELKRRLNGELPAEWEEKANQIIADLQANPANIASRKASQNALEAFGQMLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQMASLRLTPNMNTWRPCDQVESAVAWKLAIERKDAPTALIFSRQNLAQQERTAEQVTDIAKGGYILKDSDGKPELILIATGSEVELAVKAAEQLTAEGKKVRVVSMPSTDAFDKQDAAYREAVLPSDVTARIAIEAGIADFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFTVENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: ATPL_ROSDO
Sequence: MEGELAHIGAGLAAIGSGAAAIGVGNVAGNYLAGALRNPSAAASQTATLFIGIAFAEALGIFAFLVALLLMFAV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.