PharMolix/UniProtQA huggingface dataset:
Protein: CHLB_THEVB
Sequence: MKLAYWMYAGPAHIGTLRIASSFKNVHGIMHAPLGDDYFNVMRSMLERERDFTPVTASIVDRHVLARGSQEKVVDNIIRKDTEEHPDLIVLTPTCTSSILQEDLQNFVRRASLSTTADVLLADVNHYRVNELQAADRTLEQIVQFYIDKARRQGTLGTSKTPTPSVNIIGITTLGFHNQHDCRELKQLMADLGIQVNLVIPAAATVHDLQRLPQAWFNLVPYREIGGLTAQYLEREFGQPSVRITPMGVVETARCIRAIQGVLNAQGAGVNYEAFIEQQTREVSQAAWFSRSIDCQNLTGKKAVVFGDNTHAAAMTKILSREMGIHVVWAGTYCKYDADWFRAEVAGFCDEVLITDDHTVVGDAIARVEPAAIFGTQMERHVGKRLNIPCGVIAAPIHIQDFPVGYRPFLGYEGTNQLVDLIYNSFTLGMEDHLLEIFGGHDTKAVIHKGLSADSDLTWTAAGLAELNKIPGFVRGKVKRNTEKFAREQGISEITVEVLYAAKEAVGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: YQ54_BPP4
Sequence: MFDFPQPGEIYRSAGFPDVAVVGILEDGIPWEMPYRCPDIVWNPYRRKFSILVRILADGRTTDIPLGRFLREFTCDRPDLFKRSPVNRHAVLKEMAGDPELQKWREKYLDIYPQDTVPVSRAAPVAREWREIPRTEPDPETTPDNSYRNYL
What are the official names of this protein?
Uncharacterized protein ORF151.
Protein: RX2_ORYLA
Sequence: MHLSMDTLGMVDDSGHGIVDSYDMAKGAGSSNGGRVHSIDVILGFTKDQEPLLHSVGDDGSPKVNGALQQDPAKPVPSEPYGNLPELGDSSQHHSYHDSSLFSSDKCEEMSNLTKEVDIADGSPKSIKEEEHGKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELATKVNLPEVRVQVWFQNRRAKWRRQEKMDTSTMKLHDSPMLSFNRPPMPPSVGQVANPMPLDPWLTSPISSATPMHTIPGFMSSPQTLQPTYSSHSFLNSPPGMVQGMQPMGPPAYQCAPPFNDKYPVEDDRNSSIAALRMKAKEHIQSMDKTWQHM
What is the function of this protein?
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.
What are the official names of this protein?
Retinal homeobox protein Rx2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RABP_DICDI
Sequence: MNPNKIIDLKIITVGNYGVGKSSILKRFHQVDLDDNTTGFKTKKFIIDNHHVSVQTWDTSGQERFCSLSSSFYRNCDGVILCFSVDNEDSFKALDLWRDELIKFGYFPDRVPFILVGNKFDLEFKKHVINSKMAQDWCKYQKLKYQVGVNKELPDIIYHETSIEKLVSIDEAFINICRQAFENKIKISLSKLNNNNNNNEENNNNNNNNENNNYNNVPIFQIGQKIRSCCYY
What are the official names of this protein?
Ras-related protein RabP.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: STGL2_ARATH
Sequence: MAHFMKLLVTIALTTVVTIAIVTTKTTTKTATFALEDPFKDLTPPGTIKIRPSRFLAEKVDKGKEPKARNPNAADHCNKDNEICSSSDYSTGANATMACCNNKCMDLSTDDKNCGLCKNKCKFGQTCCRGQCVYVAYDKRHCGECNHRCDLGEFCVYGLCNYA
What are the official names of this protein?
Stigma-specific STIG1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the STIG1 family.
Protein: PON1D_ANOEM
Sequence: RSLCSNGCRPKPFGGCSC
What are the official names of this protein?
U1-poneritoxin-Ae1d, U1-PONTX-Ae1d, Poneratoxin.
What is the protein family that this protein belongs to?
Belongs to the poneritoxin-Ae1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN706_HUMAN
Sequence: MARGQQKIQSQQKNAKKQAGQKKKQGHDQKAAAKAALIYTCTVCRTQMPDPKTFKQHFESKHPKTPLPPELADVQA
What is the function of this protein?
Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal.  Acts by repressing expression of KLF4.
What are the official names of this protein?
Zinc finger protein 706.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NGFV_DRYCN
Sequence: MSMMCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLDNEDTLNRNIRAKRENHPVHNQGEHSVCDSVSDWVIKTTATDIHGNMVTVMGDINFTNEVYKQYFFETKCRNPNPVPSGCRGIDSKVWNSYCTTTQTFVKALTMEGSRASWRFIRIDTACVCVISRKTENF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: COMD9_BOVIN
Sequence: MAALTAENFAALQSLLKASSKDVVRQLCQESFSSSALGSKNLLDVTCSSLSVTQEEAEQLLQALHRLTRLAVFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSAWRAEAQVNQISLPRLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQEDPSLCGDRPSVSDVTVELSKETLDTMLDGLGRIRDQLSAVASK
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes.  May down-regulate activation of NF-kappa-B.  Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits.
What are the official names of this protein?
COMM domain-containing protein 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasmic vesicle.
Protein: DHTK1_HUMAN
Sequence: MASATAAAARRGLGRALPLFWRGYQTERGVYGYRPRKPESREPQGALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAGLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA
What is the function of this protein?
2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC) (PubMed:29191460, PubMed:29752936, PubMed:32303640, PubMed:32633484, PubMed:32695416).  Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC (PubMed:29191460, PubMed:32695416).  Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST) (Probable) (PubMed:29752936, PubMed:32303640, PubMed:32633484).  Can catalyze the decarboxylation of 2-oxoglutarate in vitro, but at a much lower rate than 2-oxoadipate (PubMed:29191460, PubMed:29752936, PubMed:32633484, PubMed:32695416).  Responsible for the last step of L-lysine, L-hydroxylysine and L-tryptophan catabolism with the common product being 2-oxoadipate (Probable).
What are the official names of this protein?
2-oxoadipate dehydrogenase complex component E1, E1a, OADC-E1, OADH-E1, 2-oxoadipate dehydrogenase, mitochondrial, Alpha-ketoadipate dehydrogenase, Alpha-KADH-E1, Dehydrogenase E1 and transketolase domain-containing protein 1, Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: NUOA_PECAS
Sequence: MSTTTEILAHHWAFALFLIIAIGLCVFMLTGGFLLGGRAKGRAKNVPYESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLYAWAVSIKESGWIGFIEATIFILVLLAGLIYLVRVGALDWTPVRSKRQVVKSDIINTTNTHPQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_PECCP
Sequence: MSGEGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIWAQLSAPIRIFQAVRQARAIMRRYQPDVVLGMGGYVSGPGGLAAWLCGIPVVLHEQNGIAGLTNRWLSHIAKKVLQAFPGAFPKADVVGNPVRTDVLALPVPETRLADRSGPVRVLVVGGSQGARVLNQTLPGVAAQLGERVTIWHQVGKGALSTVQQAYQDVGQTQHKITEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQFNVAAVSEVLSGWDRATLLTMAQKARAVAIPDATDRVAAEVSAAAGSRATHVAHG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: APAG_RHIME
Sequence: MYRALTRDIEVTVEPYYLEEQSDPDDSRYVWGYRIIIANHSGLAVRLMTRYWHITDENGQVDEVSGPGVIGEQPLLNPGDTYEYSSGCPLDTPSGVMFGHYSMEAEGGETFDVAIPAFSLDSPGLVRTLN
What are the official names of this protein?
Protein ApaG.
Protein: CYSH_BACC1
Sequence: MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPELTLDEQANLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFRSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_PELPB
Sequence: MSDPVIKRALVSVSDKTGIVEFCRELSGMGVEIFSTGGTLKSLQDSGVSASSISTITGFPEIMDGRVKTLHPKIHGGLLAVRENPEHVKQATENGISFIDLVVVNLYPFEATVARPDVTFEDAIENIDIGGPSMLRSAAKNNESVTVVTDSADYALVLQEMREHNGATKRTTRLTLALKVFELTSRYDRAIASYLAGAVAGEQQGAASKMTVTLERELDMRYGENPHQSAGLYRLTDENGTRSFGDFFEKLHGKELSYNNMLDIAAAVSLIEEFRGEEPTVVIVKHTNPCGVAQAPTLAEAYRRAFSTDTQAPFGGIISFNRPLDMEAAKAVNEIFTEILIAPAFEDGVLEMLMKKKDRRLVLQTNALPKGGWEFKSTPFGMLVQERDSKIVAKEDLTVVTKRQPTEEEIADLMFAWKICKHIKSNTILYVKNRQTYGVGAGQMSRVDSSKIARWKASEVSLDLHGSVVASDAFFPFADGLLAAAEAGVTAVIQPGGSIRDNEVIEAADANNLAMVFTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DEDA_ECOLI
Sequence: MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
What are the official names of this protein?
Protein DedA, Protein DSG-1.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1507_DEIRA
Sequence: MNVLQGMAAALTPLGLLWTAIIFGVSVFLHELAHYGLARAQGVRVNSFSVGMGPVLFKKLWRGTEWRVSLLPIGGYVEIDGMAPVEDADGQWRLPTRGFAALPAWGKIAVLLAGPLTNLLLTLGLMTVSFTSQGIPALDRARIESVETGSRAQALGLRAGDVITAIDGQDIPETRRVGGQEAAGYEGVRDALAQAGRHTFTVERAEQGQPVQTRQVAFDWQPTVNGQRQLLGIRYGPDVRQVGVGQAFVTSVDTTVRAVPQLVGAFTGLFKKFFTLDISQDQNVSGPIGTAEVISRAAALSPWALVQVATLLNLSLAFFNLIPIPGLDGGRILLVLVSALRGRPLSFQQEQAINLGGFAFVMLLTLFVVVRDVSRFF
What are the official names of this protein?
Putative zinc metalloprotease DR_1507.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: O5AC2_HUMAN
Sequence: MDISEGNKTLVTEFVLTGLTDRPWLHVLFFVVFLVVYLITMVGNLGLIVLIWNDPHLHMPMYLFLGGLAFSDACTSTSITPRMLVNFLDKTAMISLAECITQFYFFASSATTECFLLVMMAYDRYVAICNPLLYPVMMSNKLSAQLLSISYVIGFLHPLVHVSLLLRLTFCRFNIIHYFYCEILQLFKISCNGPSINALMIFIFGAFIQIPTLMTIIISYTRVLFDILKKKSEKGRSKAFSTCGAHLLSVSLYYGTLIFMYVRPASGLAEDQDKVYSLFYTIIIPLLNPFIYSLRNKKVMHALRRVIRK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5AC2, HSA1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADH1_SOLTU
Sequence: MSTTVGQVIRCKAAVAWEAGKPLVMEEVDVAPPQKMEVRLKILYTSLCHTDVYFWEAKGQNPVFPRILGHEAAGIVESVGEGVTELGPGDHVLPVFTGECKDCAHCKSEESNMCSLLRINTDRGVMINDGQSRFSINGKPIYHFVGTSTFSEYTVVHVGCVAKINPLAPLDKVCVLSCGISTGLGATLNVAKPTKGSSVAIFGLGAVGLAAAEGARIAGASRIIGVDLNASRFEQAKKFGVTEFVNPKDYSKPVQEVIAEMTDGGVDRSVECTGHIDAMISAFECVHDGWGVAVLVGVPHKEAVFKTHPMNLLNERTLKGTFFGNYKPRSDIPSVVEKYMNKELELEKFITHTLPFAEINKAFDLMLKGEGLRCIITMED
What are the official names of this protein?
Alcohol dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_HHV1
Sequence: MASYPCHQHASAFDQAARSRGHSNRRTALRPRRQQEATEVRLEQKMPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWQVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQGGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGEAN
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: SSRP_BORBU
Sequence: MNTNNLLLENKKAKFNYFIEEKISCGIVLKGTEVKSIKAKKLSFNNSFASIKKEELWLENLHVSKYKEGNIFNHDELRPRKLLIKKRELQRLKKFKEKEGYTLIPISFYLKKSIIKVEVGICKGKKLYDKREILKQKSIKKDLSREIKYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MURB_CHLSY
Sequence: MPVALPVTLYPDEPMARHSSWRAGGTARYYAEPATPDEAIALAAWAREQQLPLIWIGRGTNLLVRDEGFDGVIASYRGQRWELIEHGETAEVWIEAGAPMAGTARRLAAMGWAGLEWAEGLPGAVGGAIVGNAGCYGGSVAEVLITADLLLNGSECVEWSVHDLAYTYRESVLKQLLHTGIPPLVLAGRFRLQRGDPAALTARMKAIAAERKQKTPAGSSCGSVFKNPAGDFAGRLIEAAGLKGVRIGDAEISTLHANYIINRGQARAADILALIDLARTKVADQFGITLQLEVRII
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_SACEN
Sequence: MGARNKARKRAVDVLYEADLRGEDAVTLLSGRVGSPDLPPVNEYTVTLVEGVTANRQRIDELLVEHAEGWTLARMPAVDRAVLRLGLYELLWRSDDVPPAVAIDEAVELVKALSTDDSPRFVNGVLGRIAGIGDRLRSTLRGANPGAE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y4208_ALKPO
Sequence: MNEIFKELEGDCMGENVQLKDVIFNDSKYSKTKKVLAIMFITFVFLLQVNGTDKMIGFIFVFTGTVIGVTYSVCKLLFYNTKRYIKDIVFLIIFVCLFVWGIITFFNL
What are the official names of this protein?
Uncharacterized protein BpOF4_21044, ORFB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_MYCXE
Sequence: PYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGANPLALKRGIEKAVEKVTETLLKTAKEVETKEQIAATAAISAGDQAIGDLIAEAMDKVGNEGVITVEESNTFGL
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, 65 kDa heat shock protein, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_BACFN
Sequence: MIRFLGNIEAKADAKGRVFIPAQFRRQLQSGSEDKLIMRKDVFQDCLVLYPEEVWNEELDELRQRLNKWNANHQLIFRQFVSDVEIITMDGNGRILIPKRYLQITGIQSDVRFIGVDNKIEIWAKERAEKLFMEPKAFGAALEEIMKEERRTTNNELK
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: IXTPA_PYRFU
Sequence: MELFFITSNDGKVREAKKFLEPLGINVIKKPLEYPEIQADTLEDVVVFGLNWLKDKVDKPFIIEDSGLFIEALNGFPGVYSAYVYKTIGLDGILKLMEGIENRKAYFKSVIGFYDGEIHLFVGEVRGRISNEKRGLHGFGYDPIFVPDGFDKTFAEMSTEEKNSVSHRGKALKEFYRWMKENLKK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RECO_BURL3
Sequence: MGTNDALTSTEDAVTAGANDAPLPAPPEPPRKARRATSRTSDFRVAEQPAYVLHSYPYRETSLIIDVLTRDHGRLALVAKGAKRPHSALRGVLQTFQPLLLSWSGKSEVRTLTGAEWVGGMLPLGGDGLLCGFYANELLVKFCAREDPQPPLFNHYVLTLTRLAHGEPAVQVLRSFERVLLRETGYAMALNRTVARRAVEPDRRYVFDPERGVRNADDEVPSHWPVISGQTLLDMEQDDYHRAQTVAQSKTLMRFLLNTYLGGTPLATRQILIDLQNL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: FABR_ECO24
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I78A8
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNAKIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINSNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRFEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RR11_CUSRE
Sequence: MAKSIPRISSRRNGRIGSGNNVRRIPKGVIHVQASFHNTIVTVTDVRGRVVSWSSAGTSGFKGTRRGTPFAAQTAATNAIRTVVDQGMLRAEVLIKGPGLGRDAALRAIRRSGILLTFVRDLTPMPHNGCRPPKQRRV
What are the official names of this protein?
Plastid 30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid.