PharMolix/UniProtQA huggingface dataset:
Protein: MINE_BORPE
Sequence: MSFLSFLLGQKKSSASVAKERLQIILAHERGRGDSPDYLPQLQQELVAVISKYVKIDPEDIKVHLERQDTLEVLEVKIEMPQN
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RNPA_STAEQ
Sequence: MEKAYRIKRNSDFQAIYKNGKSVANRQFVVYTYKNRDLKHFRLGISVSKKLGNAVTRNRIKRAIRENFKVHKQNIIAKDIIVIARQPAKDMNTLEIQSSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GTR10_MOUSE
Sequence: MGLRPAVLLLCASVSLLGGLTFGYELAVISGALLPLQLNFGLSCLEQELLVGSLLLGALLASLVGGFLIDCYGRRRAILGSNAVLLAGSLILGLASSLPWLLLGRLSVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEVGITVGILFSYGLNYVLAGSPWGWRHMFGWAAAPALLQSLSLFLLPAGAEGTAAPKDLIPLQGRETSKPGLVKPQYSFLDLFRAQDGMWSRTVVGLGLVLFQQLTGQPNVLYYASTIFRSVGFHGGSSAVLASVGLGTVKVAATLVATGLVDRAGRRVLLLFGCALMALSVSGIGLVSFAVSLDSGPSCLATSNASQQVDLPGSSGLLVRSSLPPVLHTNGDQGQLVLSVTERPIHPVITASLGPVLNTASPVPTSPILEHTLLCWSALVCMMVYVSAFSVGFGPVTWLVLSEIYPAEIRGRAFAFCSSFNWAANLFISLSFLDLIGAIGLAWTFLLYGLTAVLGLAFIYLLVPETKGQSLAEIEQQFQTSRFPLNFGHRQRIGIQYHRLDVSSAS
What is the function of this protein?
Facilitative glucose transporter required for the development of the cardiovascular system.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 10, Glucose transporter type 10, GLUT-10.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Protein: DPOE2_CAEEL
Sequence: MDTTAEENALRREIVKTFQIHAFELKKEAVKLCVKLFLDHDKETRKKWTNKMIELLKKQTLQSSLISEELIRDTFRQCKSKGTQDAGKLLNVFDAFSLQPYDFDADLRKMVLRKEKTSLAADSSSFSHAARQRFFIVKQRAMRCASLKNFKFTTCEILGSSTKHLQSVVVLGMLTQQKADCYHIEDLSGSVEVEFKEDTKFHHALFHEHSIAIFEGTFENSVLTVNEVAMVPVESAEVTRKELSSNENWFGGDDKIAFRCSDRLRSALAKQEDTSLVFLSDVFLDDKKVMKAVFKLLQGYKDQPPVAIVFCGNFCSRPRQTDTIDLLDRGFRWLANQLTPLRKDYEKTQFIFVPGPDDPFVDTVLPRPHLPSLLFKHISPIISCTFASNPCRIQFASQEIVVFRSDLIKKTCRHSINSITVESIPSRYARSVLSQAHLCPLPQHITPVLPDFSHSLSLHPLPDLLITADRFETFTEKVVGADTIVSNPGSFSRSNYTFHVYYPCQNRVEASQIPVSELDDHSNIKNVIIFFFLF
What is the function of this protein?
Accessory component of the DNA polymerase epsilon complex (By similarity).  Participates in DNA repair and in chromosomal DNA replication (By similarity).
What are the official names of this protein?
Probable DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase epsilon subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GFRP_DANRE
Sequence: MPYILISTQIRLETGPTMVGDEYSDPSIMNYLGARKITVLGNNFSEYHVDEPPRLVLDKLDKIGYRVVSMTGVGQTLVWCLHKESSNTL
What is the function of this protein?
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1.
What are the official names of this protein?
GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the GFRP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane. Cytoplasm, cytosol.
Protein: FADI_ALIF1
Sequence: MSNSVNSSKYQPLTTRQGDRIAVVSGIRTPFAKQSTAFSTTPAVDLGKLAVKALMDKTDIDPKLIDQVVFGQVVQMPEAPNIAREIVLGTGMNIGTDAYSVTRACATSFQTTANVVESIMAGTIDIGIAGGADSSSVLPIGVSKKLASTLLALSKTKTVYQKLSLLRTLSLKDIAPVPPAVAEYSTGISMGQTAEQMAKSHGITREEQDALAHRSHTLAAKAWKDGLIQDEVMTAFPEPYTAWLDHDNNIRHDSDLASYAKLRPAFDHKYGSVTAANSTPLTDGGAALLLMSEKRAKELGYEPLGYIRSFAFSAIDVHHDMLMGPSYATPMALDKAGISLSDLTLIDMHEAFAAQTLSNVKMFASNKFAKEYLGRDKAIGEIDMEKFNVLGGSIAYGHPFAATGARMIIQTLRELKRRGGGLGLNTACAAGGLGAAMVLEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_POLNS
Sequence: MTRIHASAVVDSKAELAGDVEIGPYSVIGPNVKIGAGTKVGSHTVIEGYTTIGKENNFAHFAAIGGPPQDMKYRGEPTQLIIGDHNTVREFTTIHTGTSQDEGITRIGNNNWIMAYVHIAHDCQVGNHTIFSSNAQIAGHVQVDDWVIMGGMSGVHQFVRVGQHAMLGGASALAQDIPPFVIAAGDKASPHGINVEGLKRRGFSSETISALRQAYKVLYKDGFSFEEAKVEIQKMVAASAADAATAEKLSQFHDFIAASTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD4_MOUSE
Sequence: MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDWRALMKRKRMKANMKLVGSGFPLPTSDLDDSLTEDIDEKIAFRNDANFEWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRPTYDEPHLLMNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDLEHERLQLEKERLQIEREKWRLQLVSTEKPALENELGQGEKSMLQPQDIEAEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKERLRIQKEGHLP
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 4.
Protein: MUS81_HUMAN
Sequence: MAAPVRLGRKRPLPACPNPLFVRWLTEWRDEATRSRRRTRFVFQKALRSLRRYPLPLRSGKEAKILQHFGDGLCRMLDERLQRHRTSGGDHAPDSPSGENSPAPQGRLAEVQDSSMPVPAQPKAGGSGSYWPARHSGARVILLVLYREHLNPNGHHFLTKEELLQRCAQKSPRVAPGSARPWPALRSLLHRNLVLRTHQPARYSLTPEGLELAQKLAESEGLSLLNVGIGPKEPPGEETAVPGAASAELASEAGVQQQPLELRPGEYRVLLCVDIGETRGGGHRPELLRELQRLHVTHTVRKLHVGDFVWVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLERRVYLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRGLQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDFNAGAIKNKAQSVREVFARQLMQVRGVSGEKAAALVDRYSTPASLLAAYDACATPKEQETLLSTIKCGRLQRNLGPALSRTLSQLYCSYGPLT
What is the function of this protein?
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions.  Plays an essential role in mitosis for the processing of stalled or collapsed replication forks (PubMed:28575661).
What are the official names of this protein?
Crossover junction endonuclease MUS81.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
Protein: TP4A3_MOUSE
Sequence: MARMNRPAPVEVSYRHMRFLITHNPSNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLLKAKFYNDPGSCVAVHCVAGLGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
What is the function of this protein?
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis.  Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.  May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
What are the official names of this protein?
Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, Protein-tyrosine phosphatase of regenerating liver 3, PRL-3.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cell membrane. Early endosome.
Protein: LEU3_BIFLD
Sequence: MAKTYKIAVIPGDGIGKEVTPWAQKALEKAAEGVADFEYENFDLGAERYLRDGAILPEDEEERIKANDAILLGAVGDPRIKAGILERGLLLKLRFDLDQYVNLRPSKLYKGVTSPLANPGDIDFVVVREGTEGLYCGAGGAVRRNTPQEVATEVSINTAYGVERVVRYAFKLAMKRKKHVTLVHKKNVLVNAGDMWQRIVDKVGEEYPEVTHDYQHIDAATIFLVSDPSRFDVILTDNLFGDILTDEAGSVVGGVGYSASGCINASDEFPSMFEPIHGSAPDIAGQNKANPTAAILSAAMLLEHLGFDDAAKKIHTAVEADIEELGSTVRSTDQVGKDILARM
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_LACCB
Sequence: MTSVIFLGTPEFAVPILEGLIAQHYDILAVMTQPDRKVGRKQRLAASPVKQAAQKHDIPVLQPEKLSGSPELAQAIAMAPDLIVTAAYGQFLPTKFLEAAKIIAVNVHGSLLPKYRGGAPIQYSIMNGDSETGVTIIEMVKKMDAGDMFAQAKLPLTRADDTGTVFAKLSLLGRDLLLETLPKIIAGTATRTPQDPDKVTFSPTITKEQEHLNIHLPAKALDQWIRALRPDVGGYVYLNGQRTKLWAITPLSAGSTLPAGSIVERDKHRLVMVAGQQTTFQVDELQPAGKAKQSIADFLNGPGQQLVSGQQVITDDPE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CSGF_SALTI
Sequence: MRVKHAVVLLMLFSPLTWAGNMTFQFRNPNFGGNPNNGSFLLNSAQAQNSYKDPAYDNDFGIETPSALDNFTQAIQSQILGGLLTNINTGKPGRMVTNDFIIDIANRDGQLQLNVTDRKTGRTSTIEVSGLQTQSTDF
What is the function of this protein?
May be involved in the biogenesis of curli organelles.
What are the official names of this protein?
Curli production assembly/transport component CsgF.
Protein: RL5_BURCJ
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAIADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y933_METJA
Sequence: MEVDTMETLIRLFVSILIICVLALMIKKSRCLDNEGVIGSSIMGFILLYFCGFKYLILLLSFFILGVLVSRVGLEKKKAKKMDETCRSLKNVLANGLIPILFAILAIFGFNWALIGYISSIAAATSDTFSSELGILSNEKPRLITTFEVVEKGTDGAITIFGTLAGVLGAFLIGLFGYLLFGDIKIVLCGTAGGIAGNLADSLVGALFERKGILNNEHVNLIATIVGGIIGVLIYCTL
What are the official names of this protein?
Uncharacterized membrane protein MJ0933.
What is the protein family that this protein belongs to?
Belongs to the TMEM19 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZBT18_XENLA
Sequence: MEFPEHSRHLLQCLSEQRHQGFLCDCTVLVGDAHFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGILQFKGLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTDSTKKEEDTSSFSDKVECLSDGSSHMAGDLPSDEDDVEDEKINILPGKTDLATESRNMWIRLPTESASIPRTVGEAETHTTAAGKTAVSPCSSTGSLSHRSAISMGDSADVDCVLDLSVKSSLSGTETMNNSYLSSQEILRNSLVQVKVEKEATCDKNDIDTTEYDIERNTVKESVSSNIRASYEPVHLAPIREDSVLRELDHDDKASDDDMITLENERVQMEANTDNSLLPYVPNIISPTGQIFMCPLCNKVFPSPHILQIHLSTHFREQEGIRSKPANDVHVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSETLGLPAVRDWTLEDSSQELWK
What is the function of this protein?
Transcriptional repressor that plays a role in various developmental processes.  Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 18, Zinc finger protein 238.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TKTL1_BOVIN
Sequence: MADAEASATMADEAKPDSKTLQILRDMANRLRIHSIRATCASSSGHPISCSSAAEIMSVLFFHVMRYKQADPKNPDNDRFILSKRLSFVDVATGWLGQGLGAACGMAYTGKYFDKASYRVFCLVGDVESWEGSVWEALAFASHYSLDNLVAIFDVNRLTHSTTLPLEHSIDVYQKRCEAFGWNTLVVDGRDVEALCQVFWQAAQMKNKPTAVVAKTFKGRGIPSVEDAENWHGKPMPKERADAIIKLIESQIETNKSLEPKAPIEDSPQINISVIEMTSPPDYEISDVIATRKACGLALAKLGHANDRVIVLDGDTKNSTFSDIFKREHPERFIECFIAEQNMVSVALGCVTRGRTVAFACTFAAFLTRAFDQIRMGGISQTNINLIGSHCGVSIGEDGPSQMALEDLAMFRAIPNCTIFYPSDAISTEHAVFLAANIKGMCYIRTSRPETAIIYTPQESFEIGQAKVIRQSVNDKITVVGAGITLHEALAAADDLSKQGISLRVIDLFTVKPLDAATIISNAKATGGQIITVEDHYPEGGIGEAVSAAVSMEPDIVVHHLAVSGIPRSGKPSDLLDMFGISSKHIIWAVERILMK
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase-like protein 1, Transketolase 2, TK 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear.
Protein: XERD_SHIFL
Sequence: MKQELARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRGLTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLASPKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDISLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQMTRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerD specifically exchanges the bottom DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP82_ENCCU
Sequence: MSSNQEPLVEGKIKDKHSETHGFEVDVNQMMDTMIKSVYSSKELFLRELVSNSSDACDKLKALYFQLREKGCVLDPVTSLGIEIIPNKDNRTLTIKDNGIGMTKPDLMNFIGTIASSGTKKFREEMKEKGNSADASNLIGQFGLGFYSSYLVAERVDLITKHPSDEALVWTSTGRDVYTIEEYDGEPFAHGTSLVLYIKEGEEEFLDPKRISEIVKKYSLFVFYPIYTYVEKEIEEPEEKKDEEKEDEKVEEETAEPRVEEVREKRLKKVTEREQINVEKPLWKRNIKEVPEEELKSFYKTVSGDWDDFLAVDFWHIEGLLSIELLMFIPKRARFDMFNKNKKNNNIKLYCKNVFVTDDFGDAIPEWMSFVSGVVASDDIPMNISREMIQGTNVMKLVKKTLPQKIFEMIGKLALDAEKYKTFYKEFGNCLKMAIGEASEGQQDGYAKCLRYFTTKSGEEAISLDTYVERMAPNQKQIYVITGLSKEQVKSNPALDAFQKYEVIYMHEVMDEVMLRGLKKYKGHTIQRITSEGVELPEDEASNEEVVKSFEEFCKKVKDILSSKVEKVTVNPRLVSVPAVISTTKYSLSGTMENIMKSQPVTEANPFAAMTAVSKKIFEMNPNHQLVKNLKALFDSNEIEKMNRILEVFFETVLIHNGFVLSDPKGFCANVFDFLCSEEVRCEEPVEEVQ
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  The nucleotide-free form of the dimer is found in an open conformation in which the N-termini are not dimerized and the complex is ready for client protein binding.  Binding of ATP induces large conformational changes, resulting in the formation of a ring-like closed structure in which the N-terminal domains associate intramolecularly with the middle domain and also dimerize with each other, stimulating their intrinsic ATPase activity and acting as a clamp on the substrate.  Finally, ATP hydrolysis results in the release of the substrate.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Required for growth at high temperatures (By similarity).
What are the official names of this protein?
Heat shock protein 90.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSF_KLULA
Sequence: MGHNDSVETMDEISNPNNILLPHDGTGLDATGISGSQEPYGMVDVLNPDSLKDDSNVDEPLIEDIVNPSLDPEGVVSAEPSNEVGTPLLQQPISLDHVITRPASAGGVYSIGNSSTSSAAKLSDGDLTNATDPLLNNAHGHGQPSSESQSHSNGYHKQGQSQQPLLSLNKRKLLAKAHVDKHHSKKKLSTTRARPAFVNKLWSMVNDKSNEKFIHWSTSGESIVVPNRERFVQEVLPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSMLSNNDSRWEFENENFKRGKEYLLENIVRQKSNTNILGGTTNAEVDIHILLNELETVKYNQLAIAEDLKRITKDNEMLWKENMMARERHQSQQQVLEKLLRFLSSVFGPNSAKTIGNGFQPDLIHELSDMQVNHMSNNNHNNTGNINPNAYHNETDDPMANVFGPLTPTDQGKVPLQDYKLRPRLLLKNRSMSSSSSSNLNQRQSPQNRIVGQSPPPQQQQQQQQQQGQPQGQQFSYPIQGGNQMMNQLGSPIGTQVGSPVGSQYGNQYGNQYSNQFGNQLQQQTSRPALHHGSNGEIRELTPSIVSSDSPDPAFFQDLQNNIDKQEESIQEIQDWITKLNPGPGEDGNTPIFPELNMPSYFANTGGSGQSEQPSDYGDSQIEELRNSRLHEPDRSFEEKNNGQKRRRAA
What is the function of this protein?
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.
What are the official names of this protein?
Heat shock transcription factor, HSTF, Heat shock factor protein, HSF.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: O16G_CONCL
Sequence: GLSRPSKRCIAGGQPCEFHRGYMCCSEHCIIFVCA
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal6.1g.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIRA_HAEIN
Sequence: MMNFTLLTYLADCQPKVRSELEKFSKNLEEDIQQLREIGLDILVDGQDYRLVPMLPLLNPQQISTALFPYSIHYQPIISSTNEWILQNILSLKKGDLCVAEYQTAGRGRRGRQWLSPFAGQIMFSFYWAFDPKKSIEGLSLVIGLAIAEVLNVQVKWPNDILFDERKLGGILVEIANHKNGMLNLVIGIGINVSLSKQTEISQPYAEVCEIDPDVERQTLLPKLIQHLYTRLNIFEQNGIDEEFQQAWQSYNAFSNSEINVLTEQGVISGIEQGIDERGYLKVLCGNKIQMFNGGEVSLRKK
What is the function of this protein?
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor.  In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex.  HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
What are the official names of this protein?
Bifunctional ligase/repressor BirA, Biotin operon repressor, Biotin--[acetyl-CoA-carboxylase] ligase, Biotin--protein ligase, Biotin-[acetyl-CoA carboxylase] synthetase.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.
Protein: NUON_RHIEC
Sequence: MTAETILLSLHLSAPELILAVGALVLLMVGVFSGERSGLVVTGLAIVLLLASGLWLLFVPAEGLAFGGVYMADGFSRFMKLVALIGSLVALFMTMGHARENQLDKFEFPVLLVLATLGILLMISANDLISLYLALELQSLALYVVAAINRDSLKSTEAGLKYFVLGALSSGMLLYGMSLVYGFTGHTHFTEIAQALSVEGARSLGLIFGLVFILAGIAFKISAVPFHMWTPDVYEGAPTPVTAFFAAAPKVAAMAMLTRIVITAFQPVLADWQQVVVFISIASMLLGSFAAIGQKNIKRLMAYSSIGHMGYALVGLAAGNQTGVSGVMLYMVIYMIMTLGTFAIIMSMRRKDGTVVEDVNDLAGLSATNPFMAVVLTALMFSLAGIPPLAGFFAKYFVFVAAIEAKLYALAIIGVLASVVGAYYYLRVIKLMWFDEATGEFARVSSALRLVFGLSGLFVTAYVLIGGPIGGAAELAAATLF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRP_BOVIN
Sequence: MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN
What is the function of this protein?
Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre- Botzinger complex.
Protein: RPF1_CORGL
Sequence: MGRHSTKTSSAFTKLAASTIAFGAAATIMAPSASAAPDSDWDRLAQCESGGNWAINTGNGYHGGLQFSASTWAAYGGQEFATYAYQATREQQIAVAERTLAGQGWGAWPACSASLGLNSAPTQRDLSATTSTPEPAAAAPAVAEYNAPAANIAVGSTDLNTIKSTYGAVTGTLAQYGITVPAEVESYYNAFVG
What is the function of this protein?
Factor that stimulates resuscitation of dormant cells.  Has peptidoglycan (PG) hydrolytic activity.  Active in the pM concentration range.  Has little to no effect on actively-growing cells.  PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity).
What are the official names of this protein?
Resuscitation-promoting factor Rpf1.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. Rpf subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Upon overexpression.