PharMolix/UniProtQA huggingface dataset:
Protein: RL35_CHLT3
Sequence: MPKMKSHRGACKRFKVTGSGKVKREKMNASHILEKKSRKRKRNLHQSTLVDASQEKTVKRMILA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PVK2_CYRPO
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, CyrPo-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35_NITEC
Sequence: MPKMKTKKSAAKRFRIRAGGSIKRSQAFKRHILTKKTTKNKRQLRGMTVVHASDVASVRAMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MUTS_WOLPM
Sequence: MCNIIYNNVYQYNILKNIMSFVKEKNTPVMEQYLNLKAQYKDHLLFYRLGDFYELFFDDAIKAAKLLNIVLTKRGNSCGQEIPMCGVPAHSSESYLHKLIDLGFKVAICDQLETADEAKKRGYKSIVKRDVVRVVTPGTIIEDSLLEDKSNNYLASIVEQNDEYAISWLELSTGKFFHTLTSLKALDSDLLRISPRELLISEKFTEDEKIRSILKNYKISITQHAQSFFEYSKSHRTLCEFYKIRELGSIGNFSKVEIMACGALLEYVRVTQRGSIPRLEFPKTYKQQNFMLIDTSARRNLELFSTQFGEKKGSLISVIDHTVTASGGRLLKQMLASPLACSKAINLRLSTAQFFVNNHDSRRKIREILSNIPDIERSLSRLILGRGSPKDMNLLKIGLGKTLELSEFLCKIESGENGSLPQQYVIQTEIQPASRAGITVKSDESELSTIHKSLGNHKDLFELLNSAILDNNLSSVKEGGFIHSKYNSELSELSYILNNSNKLVTKLRESYRDLTGIAALKILHNNILGYYVEVSANHKITSDIFIHRQSLANSMRYTTNELKELENKILTARDAAIGLEMKIFSELCSEVAKESEKIALAANALAKLDIRTAFAELAVQNNYVKPIIDDSKEFNICSGRHPVVEVNDKFIANSINLAGIHLITGPNMAGKSTFLRQNALIAILAHMGSFVPAESAHIGVIDKIFSRVGATDNITAGYSTFMVEMIETATIVNQATDRSLVILDEIGRGTGVYDGLSIAQAVIEHIHNVNKCRAIFATHYHELTKVSKYLKNVKCFCVKIREWNGEVIFLHEVIEGIADESYGIHVAKLAGFPDSVLNRASEVFEELKA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: COAA_AFIC5
Sequence: MTTGAELQKYDPYRTFTREQWAKLRDDTPMTLRAEEIERMHSMLDRLDIKEVEEIYLPLSRLLSFYVSAARRLFESERRFLRIRDRKMPYIIGVAGSVAVGKSTTARVLQALLARWSPKPKVDLITTDGFLHSNAYLERAGLMDKKGFPESYNLGALLTFLSDIKAGRRDVRAPVYSHLTYDIVPNETIEIDQPDILIVEGLNVLQTGRLPADGKAVPFISDFFDFSVYIDADESTLQEWYAARFLKLRDTAFSDPRSYFHRYAGLSDEAAREKALSIWNKINRVNLRENVLPTRPRATLILKKGSDHVVERVSLRRL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPSH_PSEAE
Sequence: MLTQEQDQQLVERVQRGDKRAFDLLVLKYQHKILGLIVRFVHDAQEAQDVAQEAFIKAYRALGNFRGDSAFYTWLYRIAINTAKNHLVARGRRPPDSDVTAEDAEFFEGDHALKDIESPERAMLRDEIEATVHQTIQQLPEDLRTALTLREFEGLSYEDIATVMQCPVGTVRSRIFRAREAIDKALQPLLREA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor regulates genes such as algD, involved in alginate biosynthesis.
What are the official names of this protein?
RNA polymerase sigma-H factor, Sigma-30.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: NUOK_NEIMA
Sequence: MITLTHYLVLGALLFGISAMGIFMNRKNVLVLLMSIELMLLAVNFNFIAFSQHLGDTAGQIFVFFVLTVAAAESAIGLAIMVLVYRNRQTINVADLDELKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBEY_ALKOO
Sequence: MELLIDNRQDRYEITDALIELINKAVEACLIYEGWEIDYEVSLSFVDNQEIQALNHTYRGKDYATDVLSFPLIEENQGLDLEEKLLGDIVISVEKAAEQAKEYNHSFEREMGFLVVHSMFHLMGYDHDHDEATADMRKREEAVLTAINLLR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_MYCBP
Sequence: MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSPLSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRSVPAAHGSTLGSRVAGTQPAPVVAAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLARL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIM13_RAT
Sequence: MWHNVGLTLLVFVATLLIVLLLMVCGWYFVWHLFLSKFKFLRELVGDTGSQEGDNEQPSGSEAEEDPSASPHKMRSARQRRPPVDDGH
What are the official names of this protein?
Small integral membrane protein 13.
What is the protein family that this protein belongs to?
Belongs to the SMIM13 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDK_PELTS
Sequence: MERTYLMIKPDGVQRGLVGEIIARFEKRGFKIVGLKMIRIGRELAEKHYGEHKGKPFFEPLVGYITSSPVVAMVIEGKNAVGAAREMMGATDPLKAAPGTIRGTYGIDIGRNVIHGSDSPASAQREIALFFSADELMEYGLELDRWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_BIFAA
Sequence: MVGKSVITLDDLSIRQIQEMLHKAQYIDSHRKEVAHTCEGRVLATLFYEPSTRTRLSFETAMLRLGGKVIGFAGAQLASVTKGETIADTLKTVSNYVDVVAIRHPKEGAALVASRAASVPVINAGDGGHMHPTQTLADLATLQSRFGRVTNLTVGLCGDLTFGRTVHSLIETLCRFGNVNFVLISPDELKTPQYVLDRINATESCSYTEVKDLVSVIGDLDVLYMTRVQKERFFNEDDYLRLRDTYILDEAKMAYAKKDMAVLHPLPRVNEIAVEVDDDPRAAYFEQVKNGMLMRMALESSVVGDELPGYEPLAAKEVEA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CHEW_CERSP
Sequence: MAAVSLDEDLREVVAFRIGSQEFCIDIRAVREIRSWTPTTILPHAPSYIIGVINLRGSVVPIINLAERLGLGSLEPEARHVIIITVVEGQVVGLLVDAVSDILTLPPSSVQPMPKIASETTLSFVRGVITLDQRMLRLLDLIGVLPNVRRMM
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
What are the official names of this protein?
Chemotaxis protein CheW.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSF_CRYNH
Sequence: MTTNLYAIAGPSKPTTPTSTPSPRSEPPSPLKSLTSLPTNPLNPQGTSTSNALTNQSSSTGIGISKPGLSVDENGEVMKVPAFLNKLYTMVSDPEVDDLIYWGENGDSFFVPNAELFGRELLPRWFKHSNFSSFVRQLNMYGFHKVPHLQSGALKNETPIELWEFANPYFKRGQPQLLTKVTRKNNRLSNSGVGSSSSLGGSGAGGGMNTRSASAAAASGSGSGQIQQAISQGHEAGNHSTSGKYLITDGTTPGSAPPSHTSAGPLIAPQTLDLSAINSGIAAIRQTQASIATDLRKLQASNEALWRQAYETQEKQRKHEETIDLIVSFLERLFGTEGEGLKGLKEAMRRGVGVRRDRDGREGRDSRDARFADDDDGGQKKRRRVGLDRMIEGGSGDGTGEHGEIESPSSDDRLVEIGSNSEYSIPSVKRTSSSSHPLSLGQLGSSRFTALPSEDPSPSGSGLGSTPYEGLRTTQASAHGAGADVNVTDPTLGMNHLSPLSDTDPLLPSSSNALAPYTSHPSFPSSNPNPSSAWAFNPSQPLLSPTSAVAAAHAYNLDPSLLQTTIGSLLQSPAVAQMFLKSLSASAQGQALTSHSHPHNPSLLNPNPNGNASTSASASAHDMNTEGLGTGSGTKDLDPTLALFSPLPSHSSLASQSNDLLKSYNDALTVGEGVDNLQESIDSLVRSMGLDLPNGGSSSVGVDVGDGSGVGTGTGEGDGEFNVDEFLQGLAKEGEGEEGEREVGGDGDASSSGAGAENGRKEDVIAQSGLK
What is the function of this protein?
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription (PubMed:27866167).  Promotes thermotolerance by transiently regulating a subset of genes (PubMed:27866167).  Induces expression of STI, SSA1, SSA2, HSP78 and KAR2 during the heat response (PubMed:27866167).
What are the official names of this protein?
Heat shock transcription factor, HSTF, Heat shock factor protein, HSF.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_LACDB
Sequence: MSYRKLGWDSSQRKAMLREMTTQLIINERIVTTEARAKEVRRTAEKMITLGKRGDLAARRKAAAFVRNEIADIHEEGDEVVVKSALQKLFSDVAPRYKDRNGGYTRIMKLAVPRKGDAAPMVVLELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: THIG_NEIG1
Sequence: MLTLYGETFPSRLLLGTAAYPTPEILKQSVRTARPAMITVSLRRTGCGGEAHGQGFWSLLQETGVPVLPNTAGCQSVQEAVTTAQMAREVFETDWIKLELIGDDDTLQPDVFQLVEAAEILIKDGFKVLPYCTEDLIACRRLLDAGCQALMPWAAPIGTGLGAVHAYALKILRERLPDTPLIIDAGLGLPSQAAQVMEWGFDGVLLNTAVSRSGDPVNMARAFALAVESGRLAFEAGPVEARTKAQASTPTVGQPFWHSAEY
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCL_METM6
Sequence: MEEWVEKYRPKSLNDVAGHNKTKETLIEWIESFVSGQKQKPILLAGPPGSGKTTLAYAIAKDYAYDVIELNASDKRNKDVISQVVGTAATSKSITGRRTLIVLDEVDGLSGNDDRGGVAEIIKVLKTAENPVILTANDVYKPALMTLRNNVNLINVGSVHTNSIPPVLRKIALKEGFEIDEKVIKTIASHAGGDLRAAINDLQSLATGGSLEVEDAKELPDRDSEKSIFDAMRIIMKTTHYDIATSATRDVKEELGTIEEWISENLPKEYLKYKDLANGYDYLSKSDVFLGRVFRRQYFGLWRYASALMTAGTALAKEEKYRGFTRYAPPSIFTKLSRTKGTRQKMKDILKKIALKTHTSTKRARNTLDYMVVIFESNPEVSAELVEYYELTKEEMEFLTNKTITKNIFSVIAGKKPKVEKEIPKKKKTEEVMPIIPKRPKISELPKEPLKEVIETIEKSVENADTKEKEKKDPKKQATLDSFF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: TRPF_CHLTA
Sequence: MKVKICGITHPDDAREAAKAGADYIGMIFAKDSRRCVSEEKAKYIVEAIQEGNSEPVGVFPEHSVEEILAITETTGITSIQLSGEDILFKFSHLREHFSIFYVVSVYSNGQPSAALPPMNDAVTVVYDHIGGERGSPFDWKAFSPFQHNNWMLGGGVNLWNIKEGISLLNPRGIDVSSGVECPGILRKDIFLMQALINSAKELSSSTL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SH21A_PIG
Sequence: MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSHTETGSWIADTAPGVHKRFFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGATGRREDPDVFLKTP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7.  In SLAM signaling seems to cooperate with SH2D1B/EAT-2.  Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2.  However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1.  Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions.  Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation.  In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity).  May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 (By similarity).
What are the official names of this protein?
SH2 domain-containing protein 1A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPP1_ACRMI
Sequence: SGFHLSFSFFRRAVCGIRPTLSGFIVGGTVAPINSWPWQAKLRIAGNFLCGGSLIQPEWVLTAAHCVEGESPSIIKVTLGAHYLSTAQVVGTEQYFDVVQIIQHENYKMPKRFSNDVALLKLSRPAALRNGVGLVCLSDDQFQRPFNGTSCWTTGWGRLSWPGPVAKELMQVDLPLVSPQNCLSSYPNGYDPNTMICAGRSQGGTGACRGDSGGPLVCEFKGKWYLEGVTSWGQLPCDLPNKPTVYADVRKLKSWITGKISRSPALKVATNCSSVLNNTLKSPGYPDSYPINMFCVYRVPIPCDTELVIHFNSFHLENHVFCWYDRLRITDGSNRVIGTYCGQQTGRSVLVNDTVAVLTFKTDRSLNSSGFHLSFSFFPRGNATLLPFTTPTQTTTQRPTTTPTPGCGVVQNNTLRSPGYPSNYPRNTHCVYRVF
What are the official names of this protein?
CUB and peptidase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABZ_SYNE7
Sequence: MTVNPDAPALPTLPLAVETIQGLLPHRYPFALVDRIIDYVPGERAVGIKNVTFNEPQFQGHFPGRPLMPGVLIVEAMAQVGGVIVTLMPDMPQGLFVFAGIDQVRFRRPVVPGDQLVLSAQLLSVKRRRFCKIQGEAMVDGQLAASGELLFSLVE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_SALTY
Sequence: MNNILSEEVLNVTDFTTSRQLTLWKREDLQSPQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOL7_MOUSE
Sequence: MVQLRPRLSRIPAPAEAMVDEDQAASEEEEAEHGLLLAQPSSGAAAEPLDEEEDADDEAPEELTFASAQAEAREEELRVRASARRDKTLLKEKRKRREELFIEQKKRKLLPDAVLEQLTTASEADIKKSPENVKVNLKKKSEQHAKGRNSKKVKVQKVQSVGQIESYMAVRLKDEDLRDSRQEAAKHFIHSCLYGSDSKRTTVNKFLSLNNKRSPVKKAAAQFLTSTWGAQKQQNAKRFKKRWMAKKMKKKTYK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ODH_ARTSC
Sequence: MIESKTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTSDIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLIILNPGATGGALEFRKILRENGAPEVTIGETSSMLFTCRSERPGQVTVNAIKGAMDFACLPAAKAGWALEQIGSVLPQYVAVENVLHTSLTNVNAVMHPLPTLLNAARCESGTPFQYYLEGITPSVGSLAEKVDAERIAIAKAFDLNVPSVCEWYKESYGQSPATIYEAVQGNPAYRGIAGPINLNTRYFFEDVSTGLVPLSELGRAVNVPTPLIDAVLDLISSLIDTDFRKEGRTLEKLGLSGLTAAGIRSAVE
What is the function of this protein?
In the forward direction acts also on secondary amine dicarboxylates such as N-(1-carboxyethyl)methionine and N-(1-carboxyethyl)phenylalanine.  In the reverse direction, the enzyme also acts on neutral amino acids as an amino donor.  They include L-amino acids such as 2-aminopentanoic acid, 2-aminobutyric acid, 2-aminohexanoic acid, 3-chloroalanine, O-acetylserine, methionine, isoleucine, valine, phenylalanine, leucine and alanine.
What are the official names of this protein?
Opine dehydrogenase, N-(1-D-carboxyethyl)-L-norvaline dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the lysopine/nopaline/octopine/opine/vitopine dehydrogenases family.
Protein: UXUA_GEOSE
Sequence: MKMTFRWFGKEHDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLDDILELKRQVNEKGFHLEVIESVNVHEDIKLGLPSRDRYIENYKQTIRNLAKAGVKVICYNFMPIFDWTRSDLAKRRPDGSTVLAYEKQKIEQIDPEEMIRRIESGANGFLLPGWEPERLKTIKPLFSLYKGVTEEDLFDHLRYFLEQIVPVAEECGVRMALHPDDPPWSVFGLPRIATNKENLDRIVHMVNSPANGLTLCSGSLGANPANDVPDIFRHFLRMGRVPFAHVRNVEIHANGDFEETSHRSCDGSLNICEIMKALHEANFQGYIRPDHGRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKKKQEGEKTCSRSIQV
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: THII_COXBU
Sequence: MKKVILIKYGEIALKGKNRHLFESSIIENIRLAIGEGAPPIEQCRGRLYLQLTTEKDISCYREALKRVFGVVGFALAYRLNLEINLEEMEEVLIKHLRKLESKSLAFRVDTRRTVKSFPMDSMEINKKLGALILQHFPKWQVNLNNPELTIFIEVRDEGLFIYTTEDHEDGLGGLPVGVGGRGLLLLSGGIDSPVAGWTLLKRGMMIDAVYFHSFPYTGEKAKEKVIDLARVLTSWKLRAINLHIPYFTKIQETVNKMCPESTWTIIHRRFMMRIAEKLTKSTYHTLITGENLGQVASQTIQNIAVINQATNLPILRPLISFDKNDIIKIAEKIGTFRISKRPYEDCCALFAPKNPETKAKEEAILKAEENLPLNELINEALEKMETLRIKN
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC7B_HUMAN
Sequence: MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQYLKEHPLRQGASPRGPKPQLTEVRKHLTAALDRGNLKSEFLQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAGDIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQSYWNPLEDPPCQSPLDDPLRKGANTKTYTLTRRARVYSGENIFCPQENTEEALLLLLISESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAEKFAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFSKVKLQSLCRGPDEALLTCKHMLQIWKSCYNLTNPSDSGRGSSLLDRTIADRRQLNTITLPDFSDPETGSVHATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPFTIIPRVL
What is the function of this protein?
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.  The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis.  In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions (PubMed:26571211).
What are the official names of this protein?
Tetratricopeptide repeat protein 7B, TPR repeat protein 7B, Tetratricopeptide repeat protein 7-like-1, TPR repeat protein 7-like-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=Localizes to the cytosol and is recruited to the plasma membrane following interaction with EFR3 (EFR3A or EFR3B) (PubMed:23229899).
Protein: OBG_ECOSM
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_LACJO
Sequence: MKVRPSVKPMCEHCKIIKRQGRVMVICSANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: E1BS_ADECG
Sequence: MDPLKICENYLTFRSIIKGSTFSPGVFRRWRFHGLADVVGNIVEREEGRFWEIVPETHTLWAVFRGGFTVAPFTEILTSLQLENRGRQLAFLAFLSFLLRNWPSDSVVSEDARLDLVCAPAWSRIQIWSQAARLINDLPESVFEGQGSVVEEEQGEEHLARDSDDPFFD
What are the official names of this protein?
E1B protein, small T-antigen, E1B 19 kDa protein, E1B-19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 19 kDa protein family.