PharMolix/UniProtQA huggingface dataset:
Protein: CC175_MOUSE
Sequence: MAIRSWTPEGFVNKKLVRPASVSTNLSLELCTFPTTLGSSVAANALEQLFVVEKSLQGDYFTCSEEVKTFLKDITVAVKKLEEMRKNTVELLEIESMELSRLYFLLETVPNSIHRELEECIADARKLNIIEISQIKRKIETMNNEVKFLTNKISELKSMNEVLGAKQAELAKRHEQYVLLLNQTLEEKAAATIYINDTYTRMNFEREEIELQKQCMQETTQLIEKQKQDYLEKKEYLAIRIKETKQSCDDKRKETYYKKKELTRLQNKIIKMKQTVTSGSVMISDQSIEINILHEAITIWKKKVEDMRRLCESLEEKLSFFVTQKQNLDTTSTEKKNAFVNKIQKLGEKIYKLNTENEDLREKLSTLLKQYKATLKEEEAVSLKKQMLSEEHQKQMMVITQKEAFLSQREHDIKFMENGFGVLNDLNRASREAYGRQIEVMAKNRQREIQRCVINQWRIFCTRKRHAHWLQKIKLSLKKIIIQIEIVEQKRFQLLEETKHRKKEINHFVHLIETLKEQLAQDKKDYVKKEERLIEELGTYETLILNEIQINKVKEEELGETLPQLQVAEEDFREKNRMLRSLHSDVSAKKQDEKTMSNTIFRYRKDIIRCTDGTENMKREIKHLRDLESEKTHKHFEILKNLENEIYVNDQKMALLILENQKLREYLAYLKKEINEYASKQVVTVQHSGDLSWQLIVQHSHYSDLLSGFQIIIKELVGTGEDTMQEIKSLVAKLQYRDEKIESISTWLVGGFERLRRLMEEDSPASLSKEDLQKLGKKQKNQEILRFSPSSHARRLTLSRICKMLKKQSRSRKKKHRPRTII
What are the official names of this protein?
Coiled-coil domain-containing protein 175.
Protein: MMM1_LACBS
Sequence: MPNNYVFSLQPTFTQGLILGQLSILVLLGMILKFLFLDSTQHPFESSSVDTDLLRRKRGLEPRHLPEELLHDNAESAEWFNVLLRQIVDVYRSKLRDGLPGIEGDEIARRRIENYANKIRPSGFLDHIEIHSVDLGVSAPELFNARVRQNAPSPAETEFDATYTDTLSLSLSTSYLFNYPMQSFARLPISLTISLSQFKSSICIIPPEITSPTPVLTISISPNFVLDLSTTSLMGSRAKLANVPKLHELIQHQVRRILAARATWKVVLPGLASVVDVKEEIKKEMSDADLS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PSTB2_LATSS
Sequence: MANKIIESSDVHLFYGKNEALKGINMDFAENEITALIGPSGCGKSTYLRCLNRMNDLIDSATVTGKFLLNGQDIYAPEMDTVKLRKEVGMVFQQPNPFPFSIYDNVVYGLRLSGVKDHRVLDEAVETSLKQAAVWDDVKDKLHESALSLSGGQQQRVCIARVLAVKPKVILMDEPTSALDPISSTKIENMLLELRQQYTIIMVTHNMHQASRISDKTAFFLQGELIEYAPTKKIFLNPTEKETEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DEOB_DESHY
Sequence: MKRAILIVLDSVGIGEMPDAHEYGDVGSNTIGNIAKARGGLHLPHLQRLGLGNIAPIQGVDPEASPQGCYGKMAERSPGKDTTTGHWEIAGVVLERAFPTFSKGFPEDFLQAFAERIGRQVIGNEVASGTEIIQRLGQEHVRTGKPIAYTSADSVFQIAAHEEVIPLEELYRICGIAREMLEGDLRVGRVIARPFLGEEGNFYRTTNRHDYAIEPPHKILLDMVKEKGLRVMAVGKIKDIYAGHGVTDHLASKGNRDGVEKTLAFIREKKPGLIMTNLVDFDMLYGHRNDVENYAQALEEFDGRLPEILASLEEEDILFITADHGCDPTTESTDHSREYVPLLVYGKKVVPGRNLGIRSSFADLGATIAEYLGTEELVNGRSFLGELI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_SULNB
Sequence: MTVTRFAPSPTGYLHIGGLRTALFSWLTARHNNGKFLLRIEDTDMARNSEEAKDAILKAFEWVGMSHDGEVVYQSKRFDLYKKYIDQLLEEGKAYKCYMTKEELNALREEQMAKKERTRYDGRYRDFTGTPPEGVKPVIRIKAPQEGTISFVDGVKGAMNIAANEVDDFIIARSDGTPTYNFVVAIDDALMGLTDVIRGDDHLYNTPKQIVVYNALGFSIPNFYHVAMINNEQGKKLSKRDGATDVMEYKALGFLPEALLNFLVRLGWSHGDQEIFSVEEMIEQFDPKDINKSASNYNLDKLLWLNAHYIKNKSNSELAELLKEFGVDISEHDKLEMLLDATKERGKTLVELAEQIKLILTAPTDYDEKAVKKAFKGEAKEILTDFIAMLQTWEKPLHLPVDYHEVMEKIVAEKEIGFGKIGMPLRVSLLGSMTGAGMDEVMAIIGVDETIERIERAVSTIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN2_HUMAN
Sequence: MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508).  Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
What are the official names of this protein?
Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: SC5A4_HUMAN
Sequence: MASTVSPSTIAETPEPPPLSDHIRNAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEERIDIDAEEKSQEETDDGVEEDYPEKSRGCLKKAYDLFCGLQKGPKLTKEEEEALSKKLTDTSERPSWRTIVNINAILLLAVVVFIHGYYA
What is the function of this protein?
Has electrogenic activity in response to glucose, and may function as a glucose sensor (PubMed:13130073, PubMed:17110502, PubMed:20421923, PubMed:22766068).  Mediates influx of sodium ions into the cell but does not transport sugars (PubMed:13130073, PubMed:22766068).  Also potently activated by imino sugars such as deoxynojirimycin (DNJ) (PubMed:17110502, PubMed:20421923, PubMed:22766068).
What are the official names of this protein?
Solute carrier family 5 member 4.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAZA2_HORSE
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTAQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: HPS3_STAS1
Sequence: MELQLAIDLLNKEEAAELANKVKDYVDIVEIGTPIVINEGLPAVQYLNDNIDGVKVLADLKIMDAADYEVSQAVKFGADVVTILGVAEDASIKGAVEEAHKNGKELLVDMIAVQDLQKRAKELDELGADYIAVHTGYDLQAEGESPLESLRQVKSVINNSKVAVIGGIKPDTIKEVVAEEPDLVVVGGGIANADDPVAAAKACKDAIEGR
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase 3, HPS 3, D-arabino-3-hexulose-6-phosphate formaldehyde lyase 3.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: AGLU_SCHPO
Sequence: MMISTAYQSLFLTALFSAISIAVGNVYQTLNVIGDRNVTIPTNGIPQRLSVYDPYRGVNCQGYQAVNISESQNGVTAYLALLGEPCYAYGTDYPLLFLNVTYEEADRVHISIKDANNTQFQFTSRKDLWDAPLYSPSYNNTNLLYNFSYNANPFEFWVTRKSDGEVLFDTRGQKLVFEDQYIELTTNMVENYNLYGLAETIHGLRLGNNLTRTFWANDEPSPVDQNMYGSHPYYLEQRYKADGINSTLNETTYTSSSHGVLMLTANGMDVLLRQDYLQYRMIGGVIDLFVYSGSTESPKETVKQFVQSIGKPAMHQYWTLGYHSCRWGYTNITEIMDVRQNYIDADIPVETFWSDIDYMEKYRDFTVDPVSYSKSDMQTFFSDLVSNHQHYVPIIDAAIYAANPYNHTDDSYYPYYAGVEKDIFLKNPNGSIYIGAVWPGFTAFPDFTNPDVVDYWKDCLINLTYAFGSNGTVPFSGIWTDMNEPSSFCVGSCGSAMIDLNPAEPLTGISKQYSIPEGFNVSNVTEYSSAYSASLSNYYATATSSVFQIVSPTATPLGLKPDYNIDWPPYAINNEQGNHDIANHIVSPNATTHDGTQRYDIFNMYGYGETKVSYAALTQISPNERPFILSRSTFLGSGVYGAHWLGDNHSLWSNMFFSISGMIVFNMMGIPMVGADVCGFLGDSDEELCSRWMAMGAFSPFYRNHNNIYQISQEPYTWSSVAEASRRAMYIRYSLLPYWYTIMAKASQDGTPALRALFVEFPNDPTLADVDRQFMVGDSLLVTPVLEPNVEYVQGVFPGDNSTVWYDWYNHTEIVRQYNENVTLYAPLEHINVAIRGGSVLPMQQPSLTTYESRQNPFNLLVALDRDGSATGELYLDDGVSIELNATLSVSFTFSDGVLSAVPTGSYEVSQPLANVTILGLTESPSSITLNGQNVSSFQYSNDTEELLITGLQNITSSGAFANSWNLTL
What is the function of this protein?
Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch.
What are the official names of this protein?
Alpha-glucosidase, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_CHLTA
Sequence: MALKIRLRQQGCKNHVVYRLVLADVESPRDGKYIELLGWYDPHSEQNYQLKSERIFYWLNQGAELTEKAGALVKQGAPGVYAELMAKKVARRAVVRQKRRAYRQRLAARKAEAAAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GATC_STRPN
Sequence: MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEVDTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL36_MAGSA
Sequence: MKIRNSLKSAKLRDKNCRIVRRKGRVYVINKTNPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YEL1_YEAS1
Sequence: MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSKEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINTSDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKTTSKRNKSFFGWLKPSKTTTLIEHASRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKDIIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRKSGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAEYGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQLGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAMGSVQF
What is the function of this protein?
Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.
What are the official names of this protein?
Guanine-nucleotide exchange factor YEL1, EFA6-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the YEL1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Bud neck. Bud tip. Note=Localizes at the cell membrane only at the bud neck and bud tip and this localization is ARF3-dependent.
Protein: NP1L4_RAT
Sequence: MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEDDKLAGDMKNKVVIAEKEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKKEPIQPAECKQQ
What is the function of this protein?
Acts as histone chaperone in nucleosome assembly.
What are the official names of this protein?
Nucleosome assembly protein 1-like 4.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Present in the cytoplasm and excluded from the nucleus during G0/G1 phase, then relocates to the nucleus by the time cells are in S phase. Phosphorylated form localizes in the cytoplasm during the G0/G1 transition, whereas dephosphorylation leads to relocalization into the nucleus at the G1/S-boundary.
Protein: AC4CH_SALHS
Sequence: MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDVLRVGRFEDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: PLY22_ARATH
Sequence: MFRPNSLLIPSNLSTTKSQRNTMLNSSYLSFALIFFCCILFSALASSLPVSDPELVVEEVHRKINESISRRKLGFFSCGSGNPIDDCWRCDKDWEKNRKRLADCGIGFGKNAIGGRDGEIYVVTDPGNDDPVNPRPGTLRYAVIQDEPLWIIFKRDMTIQLKEELIMNSFKTLDGRGASVHISGGPCITIQYVTNIIIHGLHIHDCKQGGNTYVRDSPEHYGYRTVSDGDGVSIFGGSHVWVDHCSLSNCNDGLIDAIRGSTAITISNNYLTHHNKVMLLGHSDTYEQDKNMQVTIAFNHFGEGLVQRMPRCRHGYFHVVNNDYTHWEMYAIGGSANPTINSQGNRFLAPDDSSSKEVTKHEDAPEDEWRNWNWRSEGDLLLNGAFFTYSGAGPAKSSSYSKASSLAARPSSHVGEITIASGALSCKRGSHC
What are the official names of this protein?
Probable pectate lyase 22.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: NEUS_MOUSE
Sequence: MTYLELLALLALQSVVTGATFPDETITEWSVNMYNHLRGTGEDENILFSPLSIALAMGMMELGAQGSTRKEIRHSMGYEGLKGGEEFSFLRDFSNMASAEENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNSLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKAVHKSCIEVNEEGSEAAAASGMIAISRMAVLYPQVIVDHPFLYLIRNRKSGIILFMGRVMNPETMNTSGHDFEEL
What is the function of this protein?
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin (PubMed:9364046, PubMed:11557034).  May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system.  May protect neurons from cell damage by tissue-type plasminogen activator (Probable).
What are the official names of this protein?
Neuroserpin, Peptidase inhibitor 12, PI-12, Serine protease inhibitor 17, Serpin I1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Perikaryon.
Protein: HIS5_THEFY
Sequence: MQPRVVILDYGSGNLRSAQRAVARVGAHATISSDPHTALEADGLVVPGVGAFAACMRGLRALRGDRVIGKRLAGGRPVLGICVGMQILFERGVENDVVTEGCAEWPGTVERLDAPVIPHMGWNTVDAPAESAMFAGIDKDTRFYFVHSYGVRTWEMQTTSPHLKPPLVTWSTHGTPFVAAVENGPLWATQFHPEKSGDAGAQLLANWVATL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1_I80A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCERIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: SURF1_RICCN
Sequence: MKTNFLVFITFTILISLGFWQLSRLKEKKLFLASMQANLTSPAINLAEIQDGLPYHKVKITGQFLPNKDIYLYGRRSMSSEKDGYYLVTPFKTIEDKVILVARGWFSNRNKNIITQATNDRQHEIIGVTMPSEKTRIYLPANDIKNNVWLTLNLKETSKVLGLDLENFYIIAEGKDISNLDILLPLAINHLAAIRNDHLEYALTWFGLAISLIVIYVIYRRRYMAVDVIPRACSGIQKNN
What are the official names of this protein?
SURF1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRAM2_RAT
Sequence: MVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCSINMYFVVVYVQELGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGLSFLDCGRSYHLGLTARPEIYLLNTVDAVSLVSR
What is the function of this protein?
Proton-coupled metal ion symporter operating with a proton to metal ion stoichiometry of 1:1 (PubMed:9242408, PubMed:16091957).  Selectively transports various divalent metal cations, in decreasing affinity: Cd(2+) > Fe(2+) > Co(2+), Mn(2+) >> Zn(2+), Ni(2+), VO(2+) (PubMed:9242408, PubMed:16091957, PubMed:29317744) (By similarity).  Essential for maintenance of iron homeostasis by modulating intestinal absorption of dietary Fe(2+) and TF-associated endosomal Fe(2+) transport in erythroid precursors and other cells (PubMed:9242408) (By similarity).  Enables Fe(2+) and Mn(2+) ion entry into mitochondria, and is thus expected to promote mitochondrial heme synthesis, iron-sulfur cluster biogenesis and antioxidant defense (PubMed:29317744).  Can mediate uncoupled fluxes of either protons or metal ions.
What are the official names of this protein?
Natural resistance-associated macrophage protein 2, NRAMP 2, Divalent cation transporter 1, Divalent metal transporter 1, DMT-1, Solute carrier family 11 member 2.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Also found in extracellular vesicles different from exosomes.
Protein: KEX1_DEBHA
Sequence: MVIKYLLLILVQSFVAFALPFTSRSDPKAEYLVTSLPGLYSNIRTDERPLMFAGQLELYPENQTHYFFWKYQDTNQIPEAKKRTIFWLNGGPGCSSMDGALMEAGPFRINKEGEVIYNEGSWHKSGDMVFVDQPAGTGFSYSDDYDHDLDQITVEFVRFMEKFFELFPEDASNEIYFAGESYAGQYIPYIADGILRRNKNLREGEKPFNLKGLMIGNGWIAPNEQSLSYLPYSVQAGIIKTNNPRWSSILRQHQECQDIVSENDGPDGSDVSQVVSNTCERVLNLILEATRDQSAADNEQCVNMYDHTLRDSYPSCGMNWPPDLANVTPFLREQSVMNDLNLINHKKWSECSGKVGNSFRAKNSKPAIHLFPSILEEIPIMLFNGNRDIICNYIGIEGFIKKLTWNGQTGFSEDLDTLDWVYDNKTAGYIQSERNLTVVNVFDASHMVPFDKPEISRSLIDIITGNFDEKEVDNKSDMKKKSIVTYPLGVRMAKQKEESESKTSPTSVTQSKTSSISAVSGKSLATSTTLDQEHSATPSAEAERAKNQQTSNRITRLIQLLVIVVLIWGVYILYSSYRSRPSSIIKTGPSGKKKNVQWADQLRQFEEEEIEQNEQGILSRALNKLKGGDSRGTYAPTSGKTYEDIEMNEGITEHTDNRVDDFIIESDEEDAHDENQTNKQSVSK
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: ERF38_ARATH
Sequence: MERDDCRRFQDSPAQTTERRVKYKPKKKRAKDDDDEKVVSKHPNFRGVRMRQWGKWVSEIREPKKKSRIWLGTFSTAEMAARAHDVAALAIKGGSAHLNFPELAYHLPRPASADPKDIQAAAAAAAAAVAIDMDVETSSPSPSPTVTETSSPAMIALSDDAFSDLPDLLLNVNHNIDGFWDSFPYEEPFLSQSY
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF038.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.