PharMolix/UniProtQA huggingface dataset:
Protein: COSA1_HUMAN
Sequence: MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVYQFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEISESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG
What is the function of this protein?
May act as a cell-binding protein.
What are the official names of this protein?
Collagen alpha-1(XXVIII) chain.
What is the protein family that this protein belongs to?
Belongs to the VWA-containing collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: RPOA_RICFE
Sequence: MLSLSKNWNTLIKPNKVAYENFPETNNKAKIVVEPLERGFGLTLGNAMRRVLLSSLQGAAITSIKIPAIEHEFSSIPGVKEDVSEVILNIKGIEVKMHVAEKRIMKLKATGPCVITAGMIETGHDVEILNPDHVICNLAKNKQLEMELTCKVGKGYVLSTNSYEDNLPIGEIAIDALFNPVKSVTYKVENTRVGQVTDYDKLIMFVETNGDLLPEMAVGLAARILQEQLQLFISFEEQEEDKQVKTDALPFSPYLLKRVDELELSVRSANCLKNDNIIYIGDLVKRTESDMLRTPNFGRKSLNEIKEILAKFNLRFGMDVPDWPPENIQELSNRYEDSYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RNAS1_IGUIG
Sequence: QDWSSFQNKHIDYPETSASNPNAYCDLMMQRRNLNPTKCKTRNTFVHASPSEIQQVCGSGGTHYEDNLYDSNESFDLTDCKNVGGTAPSSCKYNGTPGTKRIRIACENNQPVHFELVLS
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAZE7_MYCTO
Sequence: MSTSTTIRVSTQTRDRLAAQARERGISMSALLTELAAQAERQAIFRAEREASHAETTTQAVRDEDREWEGTVGDGLG
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Putative antitoxin MazE7.
Protein: DGTP_YERPB
Sequence: MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQVGRYIAKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVEVLKLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAEENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEWGAVTPGDLFDKVVGAAFRQLGREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQLELQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRARLIQDYISGMTDLYAYDEYRRLMAAE
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: DCTA_ACIET
Sequence: MHAISSAAPAPSVRLPFYRQLYFQVVFAIIIGVLLGHFQPEYGAAMKPFGDAFIKLIKMIIAPVIFLTIVTGIASMSHLSAVGRVFGKAMAYFLTFSTLALVVGLVVANVMQPGTGMHINVAELDQTAVKGYVSKSHEMTLTGFALDIIPKTLISPFVGDNILQVLLVAVLFGVSLAMVGDAGKPILDFLDGLTKPVFKLVNIVMKAAPIGAFGAMAFTIGKFGLGSLVNLAELVLTFYITSAVFVLVVLGAVARACGFSVLKLIRYLKAELLLVLGTSSSESALPSLMEKMEKAGCSKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATDTHLTLGHQIALLLVAMLSSKGAAGVTGAGFITLAATLAVVPEVPVAGMALILGVDRFMSECRSLTNFIGNAVATVVVSRWENALDADRLHRVLDGEAEFLPEPERAVEPVVLARHRA
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_CERS4
Sequence: MSDLVAKTAIDRRLADIVTPVIEGMGFELVRLRLMSGKTRTLQIMADRPDGGIVVDECAEISTAVSAALDVEDPIEENYTLEVSSPGIDRPLTRLKDFEVWTGYEARIETTELIDGRRRFKGELAGTEGDEVLITIEDGRDSYVTIGLKFDWLADAKLILTEELIAEMLRQKKASGNFDESQFDEIEESEGEEADEAEQPPTKH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAB1_THEKO
Sequence: MKTRTRKGAVGIGTLIVFIAMVLVAAVAAAVLINTSGYLQQKSQATGRETTQEVASGIKVERVVGKTDLPYTNIGSDSTELDYIRQLAIYVSPNAGSSGIDLSNTKVILSNGEKEAVLKYAGGPDDDYDAFTKGVQNDIFDLYFKYSSDGTNWNNEHSGLAAWKNLYYTGTNHDPAKNFGIIVIQDADNSLTEDYPTLNKGDLVVLTVLVGSLEEYTGNPSNDDNAVYETGGAKYDYIDVNGNSDTTDTIQGVFGEGIPAGTKITGEVVPEFGAPGVIEFTTPSTYTEAVMELQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B1.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: POLG_LJUV1
Sequence: MAASKMNPVGNLLSTVSSTVGSLLQNPSVEEKEMDSDRVAASTTTNAGNLVQASVAPTMPVKPDFKNTDDFLSMSYRSTTAPTNPTKMVHLAHGTWTTNQHRQALVASITLPQAFWPNQDFPAWGQSRYFAAVRCGFHIQVQLNVNIGSAGCLIAAYMPKTAHDHMNTYTFGSYTNLPHVLMNAATTSQADLYIPYVFNHNYARTDSDDLGGIYIWVWSALTVPSGSPTTVDVTIFGSLLDLDFQCPRPPGADTVIYTQGKRTVRKTKTSKFKWVRNKIDIAEGPGAMNIANVLSTTGGQTIALVGERAFYDPRTAGAAVRCKDLMEIARMPSVFLGESTEPDGRRGYFTWSHTISPVNWVFDDHIYLENMPNLRLFSSCYNYWRGSFVIKLTVYASTFNKGRLRMAFFPNREGAYTQDEAQNAIFVVCDIGLNNTFEMTIPYTWGNWMRPTRGNSLGHLRIDVLNRLTYNSSSPNAVNCILQIKMGDDAMFMVPTTSNLVWQGLHSWGSEMDLVDSLDNPDEIQDNEEIQTQNVEAAQGEEAATEVGLRATENDGSLSEQLNMSQPMFLNFKKHKVNIYAASHTKVDHIFGRAWAVGVFNTETAAIQKFDLHFPTSTHGALSRFFCFWTGELNIHILNVSTTNAFLKVAHTWFGTDSGIARTATLESNGTMIIPPNEQMTLCVPYYSEVPLRCVKGSDRNSAGLGSLFTQAVGRTISNRVQIFVSFRCPNFFFPLPAPREATSRSILERVDEANAEELEAVLEARTPDAPLRLKFNPEDPLKQLREAAKAYFNIMHSDEMDFAGGKFLNQCGDVETNPGPDIELVYKNRGFYKHYGVRFGGHIYHLNSQDILSTAITGKSDFIKEEDDGKWVHAMTAPLDYFTEKYINSMVGSKHIFSATSNCETIARDLFPGRKEITQSKALGIIGVILLSASLLSLLAVPWDYSSLQTVYNQSIEGDASGLTLLSQRCMTFFSNTMCETFNNDLVKFIIKILVRLLCYIVLYCHAPNMLTTMCLGTLLVLDITTCEILSANTKALFQALVDGDVKSLVWKIAENMQFAQSKDEQAEDMAATFNFASDMVNFVPMEQMRQEGWREFNDVSMSFRHVEWWLTMFKKVYNVLKSIFAPSIEQKAVDWIDRNQEYIADVLDHASNIIIKMKDPKEQRRASTISEYFEVLKQLKPIVSLCMKVAPSTKFSSQVFRIYSEMMRVNVRVPANTDLTRLEPIGIWVSSEPGQGKSFFTHMLSTCLLKSCNLEGIYTNPTGSEFMDGYIGQDIHIIDDAGQNREEKDLALLCQCISSVPFTVPMADLTEKGTFYTSKIVIATTNKFDFTSMVLTDPAALERRFPFHLRIRAVASYSRNNKLDVARSMAAMADGSCWEYSTDGGRAWKTLSMDELVKQITAVYTQRSDALMVWKRKLNTIRNEMSPGSSTGRIFEPLEETLCALERRFGQLADSLKDNYHKTADELIEAIEDMMAPSQSPFACFAESYRPTIKYTASDKVKSWVKNHMNRWKEFVMRNKGWFTLFSVLSSFLSILTLVYLHYKKEKKEEERQERAYNPQTAISKKGGKPKLSLVKTTNFVNEAPYMQDLEHCFAQTAYISSPETQDIIHCAALSEDTILVYGHSQFYFNRYEDLRLHFKGAIFPIEGGKISQVTVNGQPMDLILVKIDKLPITFKNYTKYYTTEVGKETLLIWNSEKGRLAMPVQCVAPAGPVETMEGTITHKTYSYKVASKKGMCGGLLVTRVHGTFKVLGMHIAGNGQVARAAAVHFISNGAAGFMDQGVVVAKEKLQKPIYLPSKTALNPSPLNGVVPVKMEPAVLSPHDTRLEVIMPSVVKTAAAKYRVNIFNPDFEIWERVVDELKSKFRTKLGIHKHVSFQKAVQGFSSLSSLDLSTSPGQKYVEKGMKKRDLLSTEPFWMHPQLEGDVKDILGAVYSGKKPHTFFAAHLKDELRKKEKIAQGKTRCIEACSIDYVIAYRVVMSSLYEAIYQTPAQELGLAVGMNPWTDWDPMINVLQPYNYGLDYSSYDGSLSEQLMRYGVEILAYCHEQPEAVMILHEPVINSQHLVMDEIWHVNGGMPSGAPCTTVLNSICNLLVCTYLAYEQSLDIEVLPIVYGDDVIFSVSSPLDAEYLVQSAAQNFGMEVTSSDKSGPPKLLKMDEIEFLKRTTKFFPGSTYKVGALSLDTMEQHIMWMKNLETFPEQLVSFENELVLHGKEIYDDYKNRFNPILNQWRVCMQDYEVALHRMLRYVFD
What is the function of this protein?
Replicates the viral genomic RNA on the surface of intracellular membranes.  Covalently attaches UMP to a tyrosine of VPg, which is used to prime RNA synthesis.  The positive stranded RNA genome is first replicated at virus induced membranous vesicles, creating a dsRNA genomic replication form.  This dsRNA is then used as template to synthesize positive stranded RNA genomes.  ss(+)RNA genomes are either translated, replicated or encapsidated.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the picornaviruses polyprotein family.
Protein: PYL13_ARATH
Sequence: MESSKQKRCRSSVVETIEAPLPLVWSILRSFDKPQAYQRFVKSCTMRSGGGGGKGGEGKGSVRDVTLVSGFPADFSTERLEELDDESHVMVVSIIGGNHRLVNYKSKTKVVASPEDMAKKTVVVESYVVDVPEGTSEEDTIFFVDNIIRYNLTSLAKLTKKMMK
What is the function of this protein?
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition (By similarity).  Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs), selectively PP2CA, in an ABA-independent manner (PubMed:24165892).
What are the official names of this protein?
Abscisic acid receptor PYL13, PYR1-like protein 13, Regulatory components of ABA receptor 7.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Localizes at the plasma membrane in the presence of a CAR protein.
Protein: RL18_XANP2
Sequence: MAKDLEALARRKAKVRRAIRVAANGRPRLSVHRTSQHIYAQVIDDANGETLAAASSLEKDLRTSLKTGADTDAAKTIGKLVAERALAKGVTAVVFDRGAYIFHGRVKALAEGAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FADI_ECO24
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSDGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMSDLTLIDMHEAFAAQTLANIQLLGSERFAREVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_STAIN
Sequence: MGRDFSLKNTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAEWKNHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGANFDYAVSTLHDRLQANAAPIQLPIGAEDEFSAIIDLVTMKCFKYNNDLGTEIEEVEIPEDYRERAEEAREALIEAVAETNESLMEKIFDEQEITVDELKDAIRQATTDVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIVGHRADNPDEEVIAKADDDAEFAALAFKVMTDPYVGKLTFFRVYSGTLTSGSYVKNSTKGKRERVGRILQMHANSREEISSVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFKAHTDEETGQVIIGGMGELHLDIIVDRMKKEFNVEANVGAPMVSYRETFKTSAAVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEQGLKDAMENGVLAGYPLIDVKAKLFDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTARRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSISEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_METMP
Sequence: MKKLGTDLLKRGFAKMVKHGVVMDVTNVEQALIAEEAGATAVMALERVPADIRVQGGVARMSDPEMILEIKDAVSIPVMAKARIGHYVEAQVLESIGVDMVDESEVLTPADEVNHIDKRAFTAPFVCGARNLGEALRRIDEGAAMIRTKGEAGTGNVVEAVKHMRAVNEGIARVIGYKEMGLEAELIQMARNELKVPMELISEVAELKRLPVVNFAAGGIATPADAALMMQMGCDGVFVGSGIFKSGNPAVRAKAIVEATYNFDKPEVIAEVSKNLGEAMVGINIDEIPEEMLLAKRGI
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: NU6C_BRADI
Sequence: MDLPGPIHEILVLFLGFVLLLGGLGVVLLTNPIYSAFSLGLVLVCISLFYFLLNSYFVAVAQLLIYVGAINVLIIFAVMFVNGSEWSKDKNSWTIGDGFTSLVCITIVFSLMTTIPDTSWYGILWTTRSNQIVEQGLINNVQQIGIHLATDFYLPFELISIILLVSLIGAITMARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL14_MOOTA
Sequence: MIQQQTLLKVGDNTGARKLMCIRVLGGSKRRYASVGDVIIASVKEATPGGVVKKGDVVRAVVVRTKKAVKRPDGSYIRFNENAAVIINEQNNPRGTRIFGPVARELREKDFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HSLU_BACCN
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLPEDLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMMVKVKDKAEEQANQRLVEILVPSPQKQTGFKNPLEMLFGGNQNVNQTSESQDDTEIQKKRQEVEKQLAAGLLEEEIVSIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSFMPKKTKKRKLSVKEARKVLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGANVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSVDDFVKILIEPDNALVKQYAALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTIMEKLLEDLSFEASEITLEKVTITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FWDC_METJA
Sequence: MKELILTLQKEIIVPVEMDKVLPEVIENMSLEEIKNIELVQGRKRIKVADIFDVELNDIEGEPRIVIKNSSPKLKYIGSKMTKGEIVVEGDAGMYVGAEMKGGKIVVNGNAESWAGQNMKGGELLIKGNAGDYVGSAYRGDWRGMSGGTIIVEGNAGNEIGEFMSKGLIHIKGNVGIMAGIHQNGGIIIIDGDVDVRVGGEMKAGAIVVYGKVEEILPSFKFEGIVENPVIKLSKKDAGTPIAGTFYKFSGDYVYNKPKGQLYISVDSNPDLI
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  This enzyme is oxygen-labile.
What are the official names of this protein?
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C, Tungsten-containing formylmethanofuran dehydrogenase II subunit C.
What is the protein family that this protein belongs to?
Belongs to the FwdC/FmdC family.
Protein: RLME_ECO45
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAPT_PSEPU
Sequence: NMPEHAGASLASQLKLDAHWMPYTANRNFLRDPRLIVAAEGSWLVDDKGRKVYDSLSGLWTCGAGHTRKEIQEAVAKQLSTLDYSPGFQYGHPLSFQLAEKITDLTPGNLNHVFFTDSGSECALTAVKMVRAYWRLKGQATKTKMIGRARGYHGVNIAGTSLGGVNGNRKLFGQPMQDVDHLPHTLLASNAYSRGMPKEGGIALADELLKLIELHDASNIAAVFVEPLAGSAGVLVPPEGYLKRNREICNQHNILLVFDEVITGFGRTGSMFGADSFGVTPDLMCIAKQVTNGAIPMGAVIASTEIYQTFMNQPTPEYAVEFPHGYTYSAHPVACAAGLAALCLLQKENLVQSVAEVAPHFEKALHGIKGAKNVIDIRNFGLAGAIQIAPRDGDAIVRPFEAGMALWKAGFYVRFGGDTLQFGPTFNSKPQDLDRLFDAVGEVLNKLLD
What is the function of this protein?
Catalyzes transamination between a variety of omega-amino acids, mono and diamines, and pyruvate.  Plays a pivotal role in the metabolism of the omega amino acids.
What are the official names of this protein?
Omega-amino acid--pyruvate aminotransferase, Omega-APT, Beta-alanine--pyruvate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: MNMA_GEOSL
Sequence: MAEKHRQRIVIAMSGGVDSSVAAALLKEEGHEVIGISMQVWDYANFAAPEGEKFDTCCSLDDIHDARRVAEQIGIPFYVVNFEEEFRRLVIDDFVDEYFRGRTPNPCVRCNQRVKFELLLHKARELGADFLATGHYARRVRGEDGLYHLLRGLDPAKDQSYFLFTLTQDQLARTLFPLGEMTKEQVRRLAAERGLRVAEKGESQEICFVPDDDYVRFLEEERGTGLMAGEIVDRKGNVLGRHGGTYRYTVGQRRGLGIAHPTPLYVVGVDAERRQVIVGPAEELLATGLTATEVTWVVPPQGQTVEASCKIRYRHQPVPCTVAVRADGSAEVRFRQPEKSVTPGQAVVFYRDDEVLGGGWIEGRL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK2_SHEB9
Sequence: MKIGILSQFPQLYSTQRLVEACQSRGHEAVVINTLNCYMNINSIKPSIHYEGTELVGFDAIIPRIHASVTFYGCAVVRQFEMMGVYAANDSISIARSRDKLRALQLLSRKGIGMPVTGFANKPNDIPDLINMVGGAPLVIKLLEGTQGIGVVLAETKTAAESVIEAFLGLKANILVQEYIKESNGSDIRCFVVGDKVIASMKRQGPEGDFRSNLHLGGCGEVVKITAVERKMAIAAVKAMGLVVAGVDILRSNRGPLILEVNSAPGIEGIEQTTGISVTEPIVEYIEKMVSARKTNRPIIA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: RL23_RALSO
Sequence: MTQVAKNDHRLMQVLLSPVVSEKATLVADKNEQVVFEVARDANKGEVKAAVELLFKVEVESVQILNQKGKQKRFGRFMGRRDHVKKAYVSLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: WDR83_DICDI
Sequence: MVKISCNKVLSNHSGSVTVVKYNSDGGYCLSGSSDKSIKLYNVSKGSMIHSFEEHGYGIGDLVSTSDNKQLFSCAEKQLYQWDIASGQVIRRFQNAHNDTITSVCVNLDSTLLFSGSSDRLVKAWDLRTKSINPVQILDDAKDTITSIIVNEQTITHNHSHGHGHSHGNNNNNQPHTHTQKEVITSSVDGCIRTYDVRMGTLVTYEDTIPISSVSITKDKKCFIASCTDETVKLIDIDSYETLKEYKGHKNKVYKINSCSNFDDSLIISGSEDNDFYIYELLSGKLLSKLSGHSNIITHVDSHPSKNQFITSSTDCTIRIWDQSE
What is the function of this protein?
Molecular scaffold protein for various multimeric protein complexes.  Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists.  Also involved in response to hypoxia (By similarity).
What are the official names of this protein?
WD repeat domain-containing protein 83 homolog, Mitogen-activated protein kinase organizer 1 homolog, MAPK organizer 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MORG1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP4_THEPD
Sequence: MRGGAVTIHVKDRQIVAPGEFVGEQGRFRVEGQVFRVGRKYYSKVLGVVTVDEENRVVKVIPLKGKYFPVEGHIVVGKVVDIGFTSWEVDINSPYVAVLPVSEVTSRPVTISRNELSRILDVGDLILAKIVSFDLSKDPVLTIKESRLGKIPRGTLVEIPPQKVPRVIGRRGSMVSMIEDLLGVKLIVGQNGRIVVVGDDPQRVEIAVLAVRKIEAEAHTTGLTDRIKQFIEERLRS
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.