PharMolix/UniProtQA huggingface dataset:
Protein: FDB94_GIBM7
Sequence: MAPPSVENGSDTSTAKRRRIALACNACRLRKSRCDGTRPSCSSCVSLTLDCQYEPGESAANVIVRKQYISDLESRVYNVEQVVHRLNYFFEGHLSACATATGNATVTAAAAQSRLPRIPSPPAPSSSALEETNDGSHPHATGLEEPQDEDATTNGMAMTFVEEHTSAFFGGSSNINFTRLLLKAVNNIRNPARRLGATVDQQHELSETNLAKASRSYTNPVAASPDTGPKAMTTLPPAQEMDRMLDVYFKTAGTVFPFIHEESMRKTYTTCKASNWTRVRRTFLGTLNVIFATIASADQDAIPSARERQERSNIFFKRATALCSELSKQVISIEIVQYLVLVVIHCQGAQRSVQAWNILGLAVRSAMALGLHSAQAREGLDELQAEYSRRTWVVIYCMDKVLSVAFGRPAIIPDEYMLDQPSSSSEVAMPTPDSAGTGVDIPGDFLAVSFRLHQIMNGSLRQQYGGNVHTAEPEPDDMMSLQASGQLRKELRAWSASLPPYLRLCEPKAKIPSENTSVNRLRVILTLRYHNINMLIHRPLLCSTIRHLFLGGNSVSIDNSSYIIQLAMGEAHESLRSAQHTIELVHTIIKADPSGSNNLGVAYFTLHYVFTASLVVLGRILWAQHGQGAAADETALAMCKSLLGQVETIFQLLDHDNSLVYSCSRYINNMLEVCTAQDAIVAVQNAESGDSSAHQPPSSLAAKQLETMMHLGMGDMEMFQAYSSQIYDPALSEGLDTSSVEAATARNTDWENSFWAM
What is the function of this protein?
Transcription factor; part of the Fusarium detoxification of benzoxazolinone cluster 1 (FDB1) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  Might be involved in the regulation of the expression of the FDB1 cluster genes (Probable).
What are the official names of this protein?
Transcription factor FVEG_08294, Fusarium detoxification of benzoxazolinone cluster 1 protein FVEG_08294, FDB1 cluster protein FVEG_08294.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSA7_HUMAN
Sequence: MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKKKQKKAS
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions.  The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions.  Plays a role in hepatitis C virus internal ribosome entry site-mediated translation.  Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation.  Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
What are the official names of this protein?
Proteasome subunit alpha type-7, Proteasome subunit RC6-1, Proteasome subunit XAPC7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: CHX1_ARATH
Sequence: MDPKMLFCLPEGDALFNPLNTMFIQMACILVFSQFFYLFLKPCGQAGPVAQILAGIVLSLLTIIRKVHEFFLQKDSASYYIFFSFLLRTAFVFLIGLEIDLDFMKRNLKNSIVITLGSLVISGIIWLPFLWFLIRFMQIKGDFLTFYLAFLITLSNTAAPVVIRSIIDWKLHTSEIGRLAISCGLFIEITNIFIYTIVLSFISGTMTADIFIYSFATGVIILTNRFLASWLPKRNPKEKYLSKAETLAFIILILIIALTIESSNLNSTLFVFIIGLMFPREGKTYRTLIQRLSYPIHEFVLPVYFGYIGFRFSVNSLTKRHYLVLGMTVALSLLGKLLGVLFACSFLKIPKQYWLFLSTMLSVKGHIGLVLLDSNLMYKKWFTPVVHDMFVAALVIMTLLSGVITSLLLRSQEKSFAHIKTSLELFDTTEELRVLTCVYGVRHARGSISLVSALSGFSPGTSSSPFTPYLMHLIPLPKKRKTELLYHELDEDAGNSNGGDDEFGTNEGLEINDSIDSFTRDRKIMVRQVKLVAPMENMHEEICNATEDLRVSIVFLPFHKHQRIDGKTTNDGEVFRHMNRKVLKQAQCSIGIFVDRNITGFHQLHGSDSVQHVAALFFGGPDDREALSLCKWLTNNSQIHLTVIQFVADDSKTEKIVGDAVTKENNEVFLEIVSEDQTENETDRIFLEEFYHRFVTTGQVGFIEKRVSNGMQTLTILREIGEMYSLFVVGKNRGDCPMTSGMNDWEECPELGTVGDFLASSNMDVNASVLVVQRHRNSFDSFVDE
What is the function of this protein?
May operate as a cation/H(+) antiporter.
What are the official names of this protein?
Cation/H(+) antiporter 1, Protein CATION/H+ EXCHANGER 1, AtCHX1.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MUKF_HAEIG
Sequence: MIETSQTIPELVSWAKDREFSLNLPTERLVFLLAIAIYNNERLDGEMLEADLVDIFRHTMNAFEQSTDAIATRANNAINELVKQRLLNRFSSEFTEGLAIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASDSAEEGVENNESEHYWRRNVFAPLKYSVAEIFDSIDLSQRIMDENQQSIKNEIAELLTKDWQAAISSCERLLDETSGNLRELQDTLNAAGDKLQAQLLRIQDCVIGRDDLYFIDQLITDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFSQRLRNSIHHYFDHPWFLWTAQAERLVDLRDEEMVLREDDALGELPEELQYESLSDLHDQIVEHMQGLLIAYRENNRPIDLSLVLKEQLENYPLSRHFDVARIIVDQAVRLGMANDDLSGIYPDWQAINKRGAEVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: AROE_SYNWW
Sequence: MPLDIKTELMGLIGYPLQHSLSPLMHNLTLKKMGLNCIYLALEIEEGKLPEIPSAIRTLNFRGLNVTIPYKEKIIPFLDELSPEAAAFGAVNVIKNKNGHLHGYNTDGRGFVEALREEGIDPGERALFIGAGGAARSVAFALAGLGVSRLDFLDLDFSRARQLAEFITSRSSSLASAFLMNTLEFQRLSRTASIIINCSPVGMFPDTGKSPVSKEDLRGSRAVLCDLIYNPLQSRFLSLGQELGLETMNGLGMFVQQGALTLEILLGQKPPLDYMKEVVQNQLEKRVDPD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: DNAK_LATSK
Sequence: MSKVIGIDLGTTNSAVAVLEGGQPKIITNPEGARTTPSVVSFKNGEIQVGEVAKRQAITNPDTIASIKRHIGEAGYKVTVGDKSYTPQEVSAMILQYIKKFAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGKIAGLDVKRIINEPTASALAYGLDKTETDEKVLVYDLGGGTFDVSVLELGDGVFQVLSTNGDTRLGGDDFDEAIMNWLVENFKSDNGIDLSKDKMAMQRLKDAAEKAKKDLSGVSSTQISLPFISAGENGPLHLEMTLSRTEFDRLTSDLVDRTKAPVMNALKDAGLDANEIDKVILNGGSTRIPAVQEAVKNWTGKEPDHSINPDEAVALGAAVQGGVISGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKAQTFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGVPQIEVKFDIDKNGIVNVSAKDLGTNKEQKITIKSNSGLSDEEIDRMMKEAQENEEADTKRKEEVDLKNDVDQLIFQTDKTLKELEGKVSDEELQKAKDAKEELVKAQQENNLEDMKTKRDALSEIVQELTVKLYQQAQEAQQAAGGAEGNATDAKTDDGTVDGDFEEVKDDKE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TRUA_STRGG
Sequence: MSDQAEPGFVRVRLDLSYDGKDFSGWAKQTSRRTVQGEIEDALRTVTRSSVTYDLTVAGRTDAGVHARGQVAHVDLPEAVWAEHEEKLLRRLAGRLPLDVRIWRAAPAPAGFNARFSALWRRYAYRVGDRPGGVDPLTRGHVLWHDRPLDLDAMNEAAALMVGEHDFAAYCKKREGATTIRTLQKLRWVRDPATGVLTATVQADAFCHNMVRALIGAALFVGDGRRPAAWPAEVLAAKVRDPGVHVVRPHGLTLEEVAYPADALLAARAAEARNVRTLPGAGCC
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MRAZ_GRAFK
Sequence: MINLIGTYECKVDAKGRLMVPSALKKQLAPMMQDGFVIKRAVFQNCLELYPMEEWNVLMKRMNGLNRFKKKNNDFIRRFTAGVKTVEVDTNGRLLIPKDLVGFAGIEKEIVLSSAINIVEIWDKDKYEQTLEDSSDDFADLAEEVMGNDDFDGVS
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PLSX_IDILO
Sequence: MPELNIAIDAMGGDNGPSIVIEALEKAVHRYPDVKFTVVGHEQQLTPLLDKFNLSSHPSINLVHAEQVIEMDDKPGQSLRSKPESSMRVALQSLTDGNCQAMVSGGNTGALMTNAYFTLKTLPGVLRPALMTALPNQTGGKSYLLDLGANASCDSETLFQFGVMGAVAAEYLSGVPAPKISLLNMGEEDIKGNDVVRNAAARLAQCEQLNYIGFIEGNHLFSGRADVVVCDGFVGNVALKSCEGLATFIIDQMRDTLNSHWLYRFFFRFLQKRTHKSWDRLKPDHYNGASLIGLRHVVIKSHGSASAGAFYSAIQQAVAEAHEQLPERIKHRVEAVLSEQL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RUTD_METED
Sequence: MAAPVHHEVHGPAGGRTVLLSPGLGGSAHYFAPQVPVLAERFRVVTYDHRGTGRSPGPLEPGHDIAAMARDVLDLLDHLGIGTADIVGHALGGLIALQLALTHPERVGRIVVINGWAVMDPATRRCFAARKALLRHAGPEAFVRAQAIFLYPAPWLSENAARVANDEAQALAHFPGEETVLARISALEAFDGTAALARIPHETLLMAARDDVLVPFTASDILAAGLPNARLDLAPEGGHAHSVTRSASFNRTLLDFLASP
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: PURR_PHOLL
Sequence: MATIKDVAKHAGVSTTTVSHVINKTRFVAEDTKAAVWAAIKALNYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEIIESVENSCYSKGYTLILCNSHNNIDKQKAYLAMLAQKRVDGLLIMCSEYPEQLLGMLEDYRNIPMVVMDWGQARSDFTDTIIDNAFHGGYLAGRYLIERGHRDIGAIPGPLARNTGGGRHQGFLKALKEANIPIKEEWVIQGDFEPESGYKAMHQILNQKQRPTAVFCGGDVMAMGAICAADELGLRVPQDISVIGYDNIRNARYFSPALTTIHQPKERLGQMAFSMLLDRIINKREDAQTIEVHPRLVERRSVVDGPFVDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: HPN_HELPY
Sequence: MAHHEEQHGGHHHHHHHTHHHHYHGGEHHHHHHSSHHEEGCCSTSDSHHQEEGCCHGHHE
What is the function of this protein?
Strongly binds nickel and zinc.  Binds other metals less strongly: cobalt > copper > cadmium > manganese.  May act to increase, or at least to preserve, urease activity.  Exact function is still unknown.
What are the official names of this protein?
Histidine-rich metal-binding polypeptide.
Protein: RDRP_I01A1
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHSGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEIFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRVFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMP
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: WNT5B_HUMAN
Sequence: MPSLLLLFTAALLSSWAQLLTDANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y1477_PYRHO
Sequence: MVITLVGEKLAKPGLEFIYYGPGEPCKTCRLARVCIGNLEPGRRYKIVRVRNIEHPCPLHEGKVRVVEVVEPAIEVLMEPRYAIVGSKIKLSFVECNDDDKAELVRPEGLFEGDLVKILEIVDDVECGGRKYKLVKVMREKG
What are the official names of this protein?
UPF0179 protein PH1477.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: COAA_SHISS
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_BRUAB
Sequence: MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: YC27B_CAEEL
Sequence: MISLSLVLLLLFGVRCFDSAGQINDDSPLFISTSIDNSMNLKILVEKKPYFTGSVTGYKLYYTNDSSQTNEEYEKWMHQEALSNQNSYNFVIDANKHEIVSGDVYRVRATVFFNNVESVPTGVISINTRQSIPKAPLIVNTKILYNSSVLISFVPADDVNAIENYTLMYKQMEAEEWKSLNFKSDFDGKVLLDGLIPNHTYEIKIFVTGGIVQGTPSNLATFTTNSTALALVKTEPDEEYTADPQTNEPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFIESTIRAKSRTRSAKFTCLATNDAGDSSKEVNVIIKGPGSPPSEITLVAEKRGYTISWKPPSHPNGKITKYVVYHTLNREDPLSDWRKIDLDGSEKMVRIIMDTEESFYGRVQAATELGPGIISDIVAMERDTQPISVESDLFGVSATTMVVNPRETLSIQCTARGKPRPSISVAISDRKNASQVEVDVWSRLQATSSAGIVSAVHNFSVLTSKFVHCRAKNSAGSNYSTMELKVDKPGDAPTQIQVLSVNALDALVVWHSPQFPNSPITSYIVLVSNDDKEDKSTWLQYESNAKETQINRMLLPTGNLEKSTEYFVCVRAKNAAGIGPTSSLISFITLNGGPDSPPDNLKVLINEANQVIVYWNTPNSTTEVTGYLIYYTRDLSLSNDDYKNWQFVEMNNNSTRYKFDLSVGLKPKTFYRVRISGKNSHADGPASEVVEFETAYSEVPIPTDLKTEVLDDNTIHIKFNAVRDPDDHSKALGEYRIDLAATDDVLHALWKQIEPKSIKIDEISSMVDVEIDGDSVEKNQMYWVKVTARLDNPSWGMHSSKPRWFRTGHGKLMTSVTLEGAPLIEKEPNLFEELSVTCTGMGSPAPIITWEWMNKSIENGTEGWNILNIQIDDTTVVSKITRNNIRESGDLTCLANNNEGSSSASVEIRVLGPGNPPENIILTAYRNQINVTWQESTLPNGDIMKYIVYYSENENDDLSDWNKFETAELETYVETFGPHTKHFIRVQAVSDRGPGIISNVLSCISDVLYETIHLEIVASNILDFEAEPNQNVEIRCKGTGKPQPELFYQFANETEQNFVEVETNDMDLFEAKAPEINSRRNVTVTCRASNKYENVTISKVIIIKRPGEAPTNISWSFEEEYDSTLYINWNPIENANGEKLEYNLYLSNYKTKVSGPPVKIPDIPLDVNISLRVSAENEYGEGEKTFPIWIPTPNGGPKTAPILSSLHAQDSKVYIFWVEPRLPNGEIQNYTIYIQKENESENEEHSIDKEWKKFIYGSNITHVIIGVDDGLEENERYQMKMTATNQRHEGPETKVYTFDLISFDENDVIDNFTAIVINSTVFVEVGNPIYTKYNIYIREDGNNQTVKHEIDVESGKTTFEFPFQLDHTLSYTIKMSGMKLGRESPPSEEIDLEFISSPSPTPIISGSRRKVIKEPPL
What are the official names of this protein?
Ig-like and fibronectin type-III domain-containing protein C27B7.7.
What are the subcellular locations of this protein?
Secreted.
Protein: PMGE_HUMAN
Sequence: MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK
What is the function of this protein?
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG).  Also exhibits mutase (EC 5. 4. 2. 11) activity.
What are the official names of this protein?
Bisphosphoglycerate mutase, BPGM, 2,3-bisphosphoglycerate mutase, erythrocyte, 2,3-bisphosphoglycerate synthase, 2,3-diphosphoglycerate mutase, DPGM, BPG-dependent PGAM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AHPC_BUCAP
Sequence: MTLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKTFEAFEKRNVKIVGVSIDSVFVHQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPELNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDALNFHNKYGEVCPVNWKHGQEGMKASQEGVSSYLKKYFS
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP10_HALWD
Sequence: MKSNIKICASWQKKHEQPVYTLADTCPKCNSVTKNTAPAPFDPTDAYGEYRRALKQRVRE
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: MUTL_CLOBB
Sequence: MKRINILNEDTANKIAAGEVVERPASVVKELVENAIDANSKNILIEIEEGGSSLIRIIDDGDGIYKEDIEKAFLPHATSKIKESEDIYSINTLGFRGEALPSIASVARVNLKTKQETEECGYEITIEGGKFSEVTECGVNKGTIMEVRDLFFNVPARKKFLKTTSKESSLINDIITRIALSNPNISFKLFNNGKKIIHTYGNGNMKDVIRTIYGKSIVENVLYFEDTSDIATIYGYVGKEAIARGSRNNQSIFVNSRYIKNRSLGIAVEQAFKSFSTVSKFPFFILFIEIYPEYIDVNIHPTKSEVKFNDERFIFKKIFGAVHTSLKEEVFSTFSIPEEVNEAISKNTNLNIEEITFKIEEEQEKVKFNTNHLSQKNICSTQGNNSINKHIYDEKHKTDTNIPLNVNIPVDLKSDHIKLEDDNNSIPNKEVICDNNEVKYESSYTSDSNQYENSCKSDVDKESKSKTTGTSELVKEKIPKFPAIKIIGQYNKTYILGEYAGTLYMIDQHAAHEKIMFEKYLNDIICGDIIIQPLMIPTVIDLSMDDYSYFEENKDVFKEAGFTIEDFGGTSIALKEVPYFLGKLKPKNLFLEILDNLKNLGSGKTTEVKYNAIATKACKSAVKGNDSLDELEMVKLIEELRYIDDPFHCPHGRPTIIQFTSTDIDKKFRRIV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DAPA_ALIF1
Sequence: MFSGSIVALVTPLDTDGEVDYNSLKSLVDYHIKAGTNGIVAVGTTGESATLSVEEHVKLVMKTLEFADGRIPVIAGTGANATHEAVTFSKLFHDSGVAGCLSVTPYYNKPTQEGLFQHYKAISEATDIPQILYNVPGRTAVDLLPETVARLAELDNIVALKDATGDLDRVAITRELCGENFIQLSGDDATALDFVKLGGHGVISVTSNIAAKDMATMFALAAQGKFEEAEIINQRLMPLHNDLFVEANPIPVKWAAHRLGMITHSDIRLPLTELSLSAQPTVEQALKSAGLLK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_MYCMS
Sequence: MIRINYFNENDINMDFWKKFCNKILKTAYNYFNFNYDIELSITFVNDLKAQQINQQYRNHSYIADVTSFPVEMTENEIKAIGFRELGDMFINLNEAKRKAIKYNHDLNSEMGFLFVHGFLHLLGYDHEDSNDEKIMFDLQDQILKLNNLEYIIKFNEDDYLESN
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SER7_DROME
Sequence: MKSTRKVVGIFLATCLLPFTVLQNVAAQGSCRNPNQKQGQCLSIYDCQSLLSVIQQSYVSPEDRTFLRNSQCLDGVGRQPYVCCTSDRSFGSQEATSAAPPPTTTSSSSRGQDGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTARKSTIKQRLDLPVNDHDYCARKFATRNIHLISSQLCVGGEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETIRP
What is the function of this protein?
Serine protease which, by cleaving and activating prophenoloxidase (PPO1) after immune challenge, plays an essential role in the melanization immune response to septic wounding (PubMed:16256951, PubMed:16322759, PubMed:19071960, PubMed:24260243, PubMed:16861233).  May function in diverse Hayan-dependent PPO1-activating cascades that are negatively controlled by different serpin proteins; Spn27A in the hemolymph and Spn77BA in the trachea (PubMed:18854145, PubMed:24260243, PubMed:16322759).  Important for the innate immune response to fungi (PubMed:16861233).  Regulation of melanization and PPO1 activation appears to be largely independent of the Toll signaling pathway (PubMed:16861233).
What are the official names of this protein?
Serine protease 7, Melanization protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted.