PharMolix/UniProtQA huggingface dataset:
Protein: GPN3_MOUSE
Sequence: MPRYAQLVMGPAGSGKSTYCSTMVQHCEALNRSVQVVNLDPAAEHFNYPVMADIRELIEVDDVMEDESLRFGPNGGLVFCMEYFANNFDWLENCLGHVEDDYILFDCPGQIELYTHLPVMKQLVQQLEQWEFRVCGVFLVDSQFMVESFKFISGILAALSAMVSLEIPQVNIMTKMDLLSKKAKKEIEKFLDPDMYSLIDDSTGDLRSQKFKKLTKAVCGLVDDYSMVRFLPYDQSDEESMNIVLQHIDFAIQYGEDLEFKEPREHEEESSSMFDEYFQERQNE
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II (RNAPII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 3, ATP-binding domain 1 family member C.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: HIS6_BEII9
Sequence: MLKARVIPCLDVKDGRVVKGVNFVDLRDAGDPVQCAIAYDAAGADELCFLDITASHEDRGILLDVVERTAAACFMPLTVGGGVRTEDDIRKLLLAGADKVSIMSAAVTDRDFVRRAAEKFGSQCVVVAIDAKEVRPGAWEIFTHGGRKPTGIDAITYARDVAERGAGEILLTSMDRDGTKAGFDLALTRAVSSAVSIPVIASGGVGTLDHLVEGIAQGGAQAVLAASIFHFGTFTIAEAKHYMAQHGLPMRLDTGAAMPPGPFPAPSPPVSPAATG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_YERE8
Sequence: MSYSGERDQFAPNMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLITAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKSRMNELMAKHTGKSLEEIERDTERDRFLSADEAVEYGLVDSVFTRRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_HAEDU
Sequence: MPKIKTVRGAAKRFKKTASGGFKRKQSHLRHILTKKTTKRKRHLCHKSMVAKADQVLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RF1_CORDI
Sequence: MSQVSAVDDIVSEYQGIEAQMSDPETMGDQTLFRKLSKRYSELQPIINVNNKLVQARDDHEAAEEMAYEDKEFAAEAERLAEEIVSLEEQLADLLAPRDPHDGDDIVMEVKAGAGGEEAALFAGELVRMYQRYAEKHGFTVEVLGLSESDLGGVKDMTLSIRSKTPSRDGAWSVFKFEGGVHRVQRVPVTESQGRIQTSAAGVLVYPEPDEVAEVEIDDKDLRVDVYRSSGKGGQGVNTTDSAVRITHLPTGLVVTCQKERSQIQNKARAMQVLAARLQAMAEEQAEAEAAEGRAAQIRTMDRSERIRTYNWPENRISDHRIGYKANNLDSVLNGDLDDLFSALQAAERAERLEAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1GLT_CHICK
Sequence: MASSKSLMNLLTFSFGSAIGFFLCYLLFSMILEEQVEIQPHILHNDPHGQHSEDTDNNQLQGQMNFNADSGQHRDENRNIADGLYEKVKILCWVMTGPQNLEKKARHVKATWAQRCNKILFMSSEENKDFPTVGLETKEGRDQLYWKTIKAFQYVYDHYFDDADWFMKADDDTYVILDNLRWLLSKYSPEQPIYFGRRFKPYVKQGYMSGGAGYVLSKEALKRFVTAFKTNKCSHSSSIEDLALGKCMEIINVQAGDSRDTSGRETFHPFVPEHLLIRGYLPKTFWYWNYNYYPAVEGPGCCSDLAVSFHYVDSMTMYHLEYLVYHLRPYGYSYRYDPDSAKGLEEQNKNEAQEDNPKLKQKTSEN
What is the function of this protein?
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
What are the official names of this protein?
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DSBE_ECOLI
Sequence: MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKPVPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVGMNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHAGDLNPRVWEEEIKPLWEKYSKEAAQ
What is the function of this protein?
Involved in disulfide bond formation.  Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme.  Possible subunit of a heme lyase.  DsbE is maintained in a reduced state by DsbD.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbE, Cytochrome c biogenesis protein CcmG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: NDB43_MESMA
Sequence: MEIKYLLTVFLVLLIVSDHCQAFLFSLIPSAISGLISAFKGRRKRDLNGYIDHFKNFRKRDAELEELLSKLPIY
What is the function of this protein?
Has antibacterial activity against Gram-positive bacteria S. aureus, M. luteus, B. subtilis, and Gram-negative bacteria E. coli, and P. aeruginosa.
What are the official names of this protein?
Peptide BmKb1, Antimicrobial peptide-like protein, BmKb1', BmKb1*, Non-disulfide-bridged peptide 4.2, NDBP-4.2, Non-disulfide-bridged peptide 4.3, NDBP-4.3, Toxin peptide 6.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: RLA31_ARATH
Sequence: MGVFTFVCKNGGGAWSAKQHEGELESSASSTYELQRKLVQVSLSADSSGGVQSSFSLVSPTSAVFQVIVGGGGGGGFSAGGAASSGGGAGEAAAAPKEDEKKKEESEEEEGDFGFDLFG
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P3-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: CCMA_HAEIN
Sequence: MFEQHKLSLQNLSCQRGERVLFRALTCDFNSGDFVQIEGHNGIGKTSLLRILAGLVRPLEGEVRWDSEAISKQREQYHQNLLYLGHLSGVKPELTAWENLQFYQRISQAEQNTDMLWDLLEKVGLLGREDLPAAQLSAGQQKRIALGRLWLSQAPLWILDEPFTAIDKKGVEILTALFDEHAQRGGIVLLTSHQEVPSSHLQKLNLAAYKAE
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SUCC_FRATH
Sequence: MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQENAKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LPXK_COXBR
Sequence: MLKAPRFWYQPRSLLGGILSPFSFLYQIIVRIRRGLYAVGLKKISKFPVPIVIVGNITVGGSGKTPFVIWLANELKNRGFRPGVVSRGYGGKANRFPQTVTENSDPLQVGDEAVLLMKKIDCPMVVCRDRGAAVKHLLRNFQCDVVIGDDGLQHYSLGRDLEIALIDDRHLGNGRCLPAGPLREPKSRLNTVDFVVPKQLRPNEIYQLKNPAKKIDFNELKELTVHAVAGIGNPGYFFKQLETLGANVIAHPFRDHYFYRSEDFNFDDDHLIILTEKDAIKCKQFDDERLFCFSVDAVVPDQFQNDFFRLISNIILRKQAQREGI
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ATPE_SHEB2
Sequence: MAAMTVHLDIVSAESKIFSGRVASLQVTGSEGELGIMHGHAPLLSYIKPGMARIVKQDGSEEVFYLSGGILEVQPSTVSVLADVVMRAKDIDEQAALEAKRRAEAHMANAGADFNYDAAMVELAKAMAQLRVVETIKKNIAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PTH_FRATH
Sequence: MPKIKMIVGLGNIGKEYQDTRHNVGEWFIAKIAQDNNQSFSSNTKLNCNLAKVSIDYNNVVLVFPTTYMNNSGLAVSKVANFYKIAPAEILVAHDELDIDSGEIRLKKGGGHGGHNGLRSINQHLGTNDYLRLRIGIGHPGHKSKVANYVLSNPSIAQKKDIDSAIDNGICFLDDIINYKLEPVMQKLHTK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEDD4_MOUSE
Sequence: MSSDMAADESEAPVLSEDEVWEFCLDKTEDGGGSPGSDVTDTCEPPCGCWELNPNSLEEEHVLFTADPYLELHNDDTRVVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGILTSVQTKTIKKSLNPKWNEEILFRVLPQRHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRMERPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKNGSEDENADQAEELEPGWVVLDQPDAATHLPHPPEPSPLPPGWEERQDVLGRTYYVNHESRRTQWKRPSPDDDLTDEDNDDMQLQAQRAFTTRRQISEDVDGPDNRESPENWEIVREDENTEYSGQAVQSPPSGHIDVQTHLAEEFNTRLAVCGNPATSQPVTSSNHSSRGGSLQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGRSYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTDSNDLGPLPPGWEERTHTDGRVFFINHNIKKTQWEDPRLQNVAITGPAVPYSRDYKRKYEFFRRKLKKQTDIPNKFEMKLRRANILEDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTELDLRFIIDEELFGQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Specifically ubiquitinates 'Lys-63' in target proteins (By similarity).  Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes (PubMed:18286479).  Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes.  Involved in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19193720).  Predominantly involved in ubiquitination of membrane bound forms of ERBB4 rather than processed precursors and intermediate membrane-anchored 80 kDa fragments (m80HER4), with a lesser role in ubiquitination of ERBB4 intracellular domain E4ICD1 (PubMed:19047365).  Promotes ubiquitination of RAPGEF2.  Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity.  Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development (PubMed:20159449).  Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2 (By similarity).  Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (By similarity).  Ubiquitinates DAZAP2, leading to its proteasomal degradation (By similarity).  Ubiquitinates POLR2A (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase NEDD4, HECT-type E3 ubiquitin transferase NEDD4, Neural precursor cell expressed developmentally down-regulated protein 4, NEDD-4.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Recruited to the plasma membrane by GRB10. Once complexed with GRB10 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). May be recruited to exosomes by NDFIP1.
Protein: PSB2_STAMF
Sequence: MSGKKIVSKTTTVGIVVGDYVVLAADKRATAGSLVAHKRVKKIIRIDDYIAMTISGLVADAEIIAEQARFIARKYKLELGRPIKVSALASNLSIILNAYLRMSPYIVQLLLGGYDDNGPHLFYIDLFGSLSEEKYMATGSGSPTAFGVLEEEYRSDLSLDEAKELAFKAVSAATKRDGFSGEGVDIVVIGPNTYVEETKLFKRSIIAK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CHLTB
Sequence: MGAVSRDDYIALCTELVEHDRRYYALNQPTISDYSYDMKMRELQEIEVQHPEWKVSWSPTMYLGDRPSGQFPVVPHSSPMLSIANVYSLQELEEFFSRTEKLLGYSPGYSLELKIDGIAVAIRYEKRLFAQALSRGNGVKGEDITANVSTIRSLPMRLPQEAPEDLEVRGEVFLSYEAFEELNACQREQGKLEFANPRNAAGGTLKLLSSKEAAKRKLDLSVYGLITDQKKRSHFENLQLCSQWGFFVAGMPKQCRSRQEVVERIREIEEMRAALPMAIDGVVIKVDNIAHQDRLGLTSKHYRWAIAYKYAPERAETILEDIVVQVGKTGILTPVAELAPVFLSGSRVSRASLYNQDEIEKKDIRIGDSVYVEKGGEVIPKIVGINLAKRSLESEPWKMPSLCPVCHEPVVKEKVSVRCINPLCSGGMLEKICFFASKSALNIDHLGEKVVTKLFEVGLISSCSDIFALTEEDLKQVPGFKDRSIQNLLASIAGAKKVALDRLLTALSIPFVGSSGAIALADHFGTLDKVIEASLDELMSIEGIGPKVAASIVAFFSKHENREEIRRMQELGVQVLSKQSDKEAPLQGKVFVLTGTLQQMTRTQAEERIRSLGGKVSSSVSKSTYAVIAGSEAGGKLKKAQDLGLSIWNESKLSRILDAKSVS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL332_STRA5
Sequence: MAQKKASLACTECGSRNYSIGVSSTPKPTRLEVNKFCKYCKKYTIHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NU4LM_PIG
Sequence: MPLVYMNIIMAFAIALAGLLMYRSHLMSSLLCLEGMMLSLFIMSTLIILNTHFTLANMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UL32_EHV2
Sequence: MATSERFLPWSRATVFKHSPALARLLEHSFQPGSPETALNCPTLTATHAALLECAPCKICQLVYSLASDPACEVAFFEDYACLCFYALYAPLCWTSTFMAAADFLELVSRYFPGAVGEGGLYGPEGIMAVDLQLHFLIKRCFRPVAASELLDVCNLHFLKSEFLKGALTGSVSNLFCFKSIWGSMHAPAVKQQAGGGGCGCCGLSSSLSAAAPADKRRAGGGGGAAETRRPEFAEAVSRAFPQGGGRAQTGVKPELLSVFLDVWGESDLLSEANREMAAAAPARAAGALGRFEFTYPETADRCQGPCMLSQALQLKKSNRTASICVLCECIAGHAEGAEALRLLKRDILTFVENNVKIPDRISFIVRQRDSLVYVRDPLLRGVIRGCSEQEIHKHLFCDPLCALNSASACPDILFGEPGEEELRILKSSLAIGNHLAENIFLDCEVLHTLVIIFKSIQLCKVGKTTFLEIIKELNHQLKNHNLQTLHTFHTATIYC
What is the function of this protein?
Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.
What are the official names of this protein?
Packaging protein UL32 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL32 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: AZO1_STAA8
Sequence: MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPLNQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDYFKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLNDSEFQLRARLFVDQIVSFVNNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: CLCA_SHIFL
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMGLGREGPTVQIGGNISRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRET1_POLVA
Sequence: MELNNKEDSPRHTVPFVRQITEDGKAKLEIYRPTTNPIYIYTQILAAIAVSMGSMVVGFASAYTSPALVSMQNTTITSFKVTEQEASWVGGIMPLAGLAGGIAGGPFIEYLGRKNTILATAVPFIVAWLLIAFANSIWMVLAGRALSGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILICFVAGKYVNWSGLAFIGSILPIPFMVLTLLIPETPRWFVTRGREERARKALQWLRGKKADVEPELKGIVKSHCEAERHASQNAIFDLMKRSNLKPLLIALGLMFFQQLSGINAVIFYTVSIFKDAGSTIDENLCTIIVGVVNFGATFFATVLIDRLGRKILLYISEVAMVITLLTLGTFFYYKNSGNDVSNIGWLPLASFVIYVIGFSSGVGPIPWLMLGEILPGKIRGSAASVATGFNWTCTFIVTKTFADIVAAIGNHGAFWFFGVICLIGLFFVIFFVPETQGKSLEEIERKMMGRVRRMSSVANMKPLSFNM
What is the function of this protein?
High-capacity facilitative transporter for trehalose, required to induce anhydrobiosis.  Anhydrobiotic larvae can survive almost complete dehydration.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph.
What are the official names of this protein?
Facilitated trehalose transporter Tret1, PvTret1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSX_MAGSA
Sequence: MSAAVTISIDAMGGDAAPDMVVEGVRMAHERLPHVRYLMFGDASRIEPLLARFPEIRGVCTIHHTEESVSMEAKPSQVLRQGRKSSMWLAVEAVQKGEAAGIVSAGNTGALMAVSKFVLRMLPGIDRPAIAGMFPTVKGETLMLDLGANVDCNSNNLVEFAVMGEVYARAVLGLEKPSIGLLNVGSEDMKGNDAVKAAAAALRDSHLPISFYGFVEGNDICGGTVDVVVTDGFTGNIALKTAEGTVKLYSTFLKEGFQSSLLAKFGYLFARHAINKVKVRTDPRRYNGAMFLGLNGIAVKSHGGTDAFGFANAVGVAVELVTHGYNDRIRKEFDRLKPAEVSPSQLAAGTR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TYLM1_STRFR
Sequence: MAHSSATAGPQADYSGEIAELYDLVHQGKGKDYHREAADLAALVRRHSPKAASLLDVACGTGMHLRHLADSFGTVEGLELSADMLAIARRRNPDAVLHHGDMRDFSLGRRFSAVTCMFSSIGHLAGQAELDAALERFAAHVLPDGVVVVEPWWFPENFTPGYVAAGTVEAGGTTVTRVSHSSREGEATRIEVHYLVAGPDRGITHHEESHRITLFTREQYERAFTAAGLSVEFMPGGPSGRGLFTGLPGAKGETR
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin.  Involved in the last step in mycaminose biosynthesis by mediating dimethylation of the hexose C-3' amino group.
What are the official names of this protein?
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, Tylosin biosynthesis protein M1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TylM1/DesVI family.
Protein: LPXB_CAMJE
Sequence: MKTFLVCALEPSANLHLKEVLKAYKKDFGEFELHGIYDESLCKEFDLNSKPLYSSHEFSAMGFIEVLPLIFKAKKAIKELANLSFTQKINGILCIDSPAFNIPFAKALKKAGSKIPRIYYILPQVWAWKKGRIPIIESHFDILASILPFDNQFFNKSTYIGHPLLDEIKEFKNQEDINHTFSKKDDEKTIAFLPGSRRSEIRRLMPIFKELSQKFKGKKILCVPSFNLEKLEVYGDISEFKIESNTPKVLKKADFAFICSGTATLEAALVGTPFVLAYKAKAIDIFIAKLFVKLKHIGLANIFCDFAGKEALNPEFLQDKVNVLNLYEAYNKYDYKAFFAKVDFLKEYLQFGSAKNLAKILNEI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.