PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_THEFY
Sequence: MSIIEAIILGLVQGLTEFLPISSSGHLRIVAAFSGWPDPGAAFTAVSQIGTELAVLIYFRKDVGNILATWFRSLGNKELRRHIDARMGWYVIIGSIPIGVAGLLFEEQISAPFRDLRLTALTLIVFGVLLGMVDRYSRKHRELTDLNAQRGLIYGLFQMLALIPGVSRSGATVTGGMLMGFKREAAARYAFLLAMPAVFASGLYKLKDIGGNEYAGVGATIVGTLVAFAVGYAVIAWFMRFISTNSFMPFVYYRIALGILILALVSFGVLTPESGAEFEGSAASVTAAEATH
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPH2_CAEEL
Sequence: MTESAPSAFFTTSTPADHVHEEESSNTGYFENLPENDIHSFFEIDATSEWIKQGNHQRIALQFPDSLLPYSEKVTKLIESRFRSESAKKTFVLADTSYRSCCVDEVAAAHADCTALVHFGEACHSAPTDKIDVKYVLGSMPIFIDQFRMEFQNVADQLTAEHIVLLMDSCFSHEQEKVAAVIKEVLPGNRHVECSLLPSEDVLKQNRQNIYLGREIPSCLRNNQPTDLIFCGFPNSPLLPIWLLSYPSCSTVSHFNPINKTIQHESTRSSRLLRKRLFLVEKLKDADTVGLVVGSVGVDKHREAVKRMREMCKKAGKKIYVISVGKINVPKLSNFSTDIDVFVLLSCPFGVVLDSSDYFRPVVSYFEAEIALNPAKTWAADFGWSAEFAAFLEDKIETEVPDDKAAGDFSLISGKVRVQKTEEEKNGDGPSSVAIYNPGYCNDRTWKGLNDGVSTAEDSTKMGEGRSGIAQGYSGK
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  Dph-1 and dph-2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph-3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph-1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: EFTS_RHOPA
Sequence: MATITAAMVKELRETTGVGMMDCKQALAETDGNIDAAIDWLRKKGLSKAAKKAGRVAAEGLIGALTDGTKGVVIEVNSETDFVARNEQFQGLVKMIAQVALKVGADLDAINAAPVGSTTVAGAIADAIATIGENMTLRRAAALSVSQGVVASYIHNAVIDGAGKMGVIVALESAGKADELAVLGRQLAMHVAAANPQALDPTSLDPAVVQREREVMADKYRQQGKPENMIEKIVENGLKTYYKEVCLLEQAYIHDEKGKSVAQAVKEAEGKVGAPIKIVGFVRYALGEGIEKQTSDFAAEVAAASGQK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_HERAR
Sequence: MQWEVVIGLETHTQLTTKTKIFSGSPTRFGAAPNTQTSPVDLALPGALPVMNRSAVERAIQFGLAIGATIAPYSVFARKNYFYPDLPKGYQISQMDLPIVQGGRVSFAMEVDGKTEIRSVQLTRAHLEEDAGKSLHEDYHGMTGIDLNRAGTPLLEIVTEPDMRSAAEAVAYAKALHTLVTWIGICDGNMQEGSFRCDANVSVRPVGQKEYGTRCEIKNLNSFRFMEDAINYEVRRQIELIEDGGRVVQATRLYDPDKKETREMRSKENAHDYRYFPDPDLPPLVVSAEWITRVQAEMPELPGAMRERFTREYGLSDYDAAVLTQSKAMANYFELICSIAGHEQAKPAANLLMGDVASAVNRDGIELDAAPVSAAQLAVLLHRIADGTISNKIAKEVFGAMWEAKSDSPTIADELIESKGLKQISDSGALEKIVDDVLAANTKSVEEFRAGKEQAINALMGQAMKASKGKANPAQLTELLKKKLSA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: CRTN_STAAE
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: SIAM_XENTR
Sequence: MTCEAEMEQIVSTALTLQEDYIKFTPRNPTMACHTEIIGVFHDIHPTVEKNKEAHRDKLVLQETLVELYSVLGIPQEPQVGKTMKFEEPEQHRGSARFDPLVNSLQLKRPLYEEERRECKRPLVQADEAVAAPSARSRRRTIYSKEQTHFLQNQFDLNPYPDFVNRCRIAKITAIPEPRIQVWFQNRRARHLPRAATSLSPQERKPPGSVGPRSSLCREAQHPEAWSEVLIPSDSQPHPN
What is the function of this protein?
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center.  Acts as a transcriptional activator, cooperating with TGFbeta signals to induce a program of organizer-specific gene expression and to generate an organizer with both head- and trunk-inducing activity.  Activates the head organizer gene cer1 by acting synergistically with otx2 and mix-A/mix. 1 through the 5'-TAATCT-3' element of the cer1 promoter.  Also binds as a complex with lhx1/lim1 and mix-A/mix. 1 to the 3x 5'-TAAT-3' element of the cer1 promoter.  Required for subsequent dorsoventral axis formation in the embryo, dorsalizing ventral mesoderm and cooperating with t/bra to induce dorsal mesoderm.  Also involved in neural induction, inducing the cement gland and neural tissue in overlying ectoderm.  Later in development, has the second function of indirectly repressing ventral genes, probably by activating the expression of a transcriptional repressor (By similarity).
What are the official names of this protein?
Homeobox protein siamois.
What are the subcellular locations of this protein?
Nucleus.
Protein: ULAE_SHIDS
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRGIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGMGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
Putative L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: CLPS1_AGRFC
Sequence: MIAKPIYMQGEGDGEDGGTNRGTSVITRVKPKTKRPNLYRVLLLNDDYTPMEFVIHILERFFQKDREAATRIMLHVHQHGVGECGVFTYEVAETKVSQVMDFARQHQHPLQCVMEKK
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS 1.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RTCA_ECOL5
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITGIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGVHQQTTLLRHGFYPAGGGVVATEVSPVASFNSLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAASFSLHEQAVHSLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGTGEFTVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ECOL6
Sequence: MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQMFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_VARPS
Sequence: MRLILLGAPGAGKGTQAAFICQKYGIPQISTGDMLRAAVKAGTPLGQQAKAVMESGGLVSDDLIINLVKERIAQPDCAGGFLFDGFPRTIPQADAMKAAGVKLDYVLEIDVPFSDIIERMSGRRSHPASGRTYHVKFNPPKVEGKDDITGEDLIQRKDDEEETVRKRLEVYSQQTRPLVDYYSAWAKADPASAPKYRAIQGVGSVEEIKQRALAALSS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_STRS2
Sequence: MTKEFNHTTVLLHETVDMLDIKPNGIYVDATLGGAGHSEYLLSQLTDGGHLYAFDQDQTAIDHAHIRLASYIEKGQVTFIRDNFRNLKTRLAELGVTEIDGICYDLGVSSPQLDERERGFSYKQDAPLDMRMNREGHLTAYDVVNNYDYHDLVRIFFKYGEDKFSKQIARKIEQARAVKPIETTTELAELIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAIDLLALDGRISVITFHSLEDRLTKQLFKEASTIDVPKGLPFIPDDLKAPLELVNRKPILPSQEELEANNRAHSAKLRVAKKVHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_THIDA
Sequence: MQNQKIRIRLKAFDYKLIDQSALEIVETAKRTGAVVKGPVPLPTSIERFDVLRSPHVNKSSRDQFEIRTHRRLMDIMDPTDKTVDALMKLDLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TBP3_METAC
Sequence: MESTITIENVVASTALATEFDLVKIMDSGLEGAEYNKTKFPGLVYRIDNPKAAFLIFTSGKVVCTGAKTINNAHKAITNLANKLKDIGCDKINLEPEIHVQNIVASADLKTTLNLNTIAIAFGLENVEYEPEVFPGLIYRVEAPKVVVLVFSSGKLVITGGKCEEDCNGGLRIVRKEFDNLGLLC
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein 3, Box A-binding protein 3, BAP 3, TATA sequence-binding protein 3, TBP 3, TATA-box factor 3.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: YJGA_SALA4
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAELVDLGKNALDKIPLDADLRDAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLEHLRDRLIVEGDDAVAEVLTLWPHADRQQLRSLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: GPH_PSEPK
Sequence: MSGFEQLFPGTLPRLVMFDLDGTLIDSVPDLAAAVDRMLLELGRPPAGLEAVRHWVGNGAQVLVRRALAGGIDHADVDDALAEQALALFMDAYAESHELTVVYPGVRDTLRWLRKQGVEMALITNKPERFVGPLLDQMKIGNFFRWIIGGDTLPQKKPDPAALLFVMQMAGVTPQQSLFVGDSRSDVQAAKAAGVQCVGLTYGYNHGRPIDAESPSLVIDDLRALLPGCADPATGITLADLQASQDRESTVAVTGKFWMKVIKALARWRWRA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: ARGB_CHLSY
Sequence: MTTISVIKVSGHELDDPTFLGGLTAALRGFQQPLVLVHGGGKEISAAVERAGLQIEFVDGLRVTSPAVMDIMQMVVCGTINKRIVTALVNAGVKAIGLSGLDLGLLRCEPYRPAGRDLGRVGEVTAVDGAALLHLLALGWMPVIAPVALGATDGLSYNVNADMVAEAVAGALAGAELVFVSNVPGVLVDGRVVPALTPAAVEELIANGVISGGMIPKVRAALAALQRGASSVRIVNLAGLHDGGTRFTHGELSE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK3_TYRGL
Sequence: DPPFAPRM
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-3, PK-3.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURL_BRUMB
Sequence: MTISNTRDITPELIEAHGLKPDEYQRILELIGREPTFTELGIFSAMWNEHCSYKSSKKWLRTLPTSGPRVIQGPGENAGVVDIGDGDCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVAAMNALRFGEPDHPKTRHLVSGVVSGVGGYGNAFGVPTVGGEVNFDKRYNGNILVNAFAAGLARHDGIFLSEAEGVGLPVVYLGAKTSRDGVGGATMASAEFDESIEEKRPTVQVGDPFTEKCLLEACLELMASGAVIAIQDMGAAGLTCSAVEMGAKGDLGIELILDHVPVREENMTAYEMMLSESQERMLMVLKPEKEAEAQAIFRKWGLDFAIVGKTTDDLRFRVIHQGEEVANLPIKDLGDEAPEYDRPWMEPGKHAPLPASNVPQVEDYSAALLKLIGSPDLSSRRWVYEQYDTLIQGNSLQVPGGDAGVIRVEGHETKALAFSSDVTPRYCEADPFEGGKQAVAECWRNITATGAEPLASTDNLNFGNPEKPEIMGQLVKAIEGIGEACRALDFPIVSGNVSLYNETNGQAILPTPTIAGVGLLPDWSQMAKIGGMQDGDTLVLLGGDGTHLGQSVYLRDLFDRADGPAPFVDLALEKRNGEFVRSAIRNGQVTACHDLSDGGLAIAVAEMAIKSGKGATLDAGDGLPHALLFGEDQARYVISATPEMAKLIALNAEGAGVPFRILGTVGGDRLKISKNVDVSVADLTQAYEGWFPNFMNGELTGNN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_BACAH
Sequence: MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQILKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_XANCB
Sequence: MIQTITDLSALRALVTGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFARYPRTPEADMRGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGVCRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVIRQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSADDRPISAQIRKVLLQMRDSHAAGVPRLQVEAAATQALEAVGFRVDYTALRLPDLSEPDDGASNPAAGPRVALIAARIGSTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTD_METTM
Sequence: MVVKIGIIKCGNIGTSPVLDLLLDERADRPNIDVCVVGSGAKMNPDEIERAVPTMLEMERDFVIFISPNPGAPGPAKARELLSAADVPAMIIGDAPGLRVKDEIEEQGLGYIIVKADPMIGARREFLDPTEMASFNSDVIKVLAFTGAYRVVQNTIDAMIADVEAGKAPELPQVVIDTDKAVEAAGYTNPYAKAKAMAAYEIATKVADIDVRGCFMVQDPDQYIPIVASAHEMLSAAAKLAIEAREIEKANDTVLRTPHGKEGKTLSKKDLLAKPE
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: METN_MYXXD
Sequence: MIAFRGVSKVYTAGGREVAALRNVSLRVEAGEIHGVLGQSGAGKSTLIRCANLLERPTEGSVSVDGQDLLALSPEALRKARQGIGMIFQHFNLFGSKTVAANVAYPLEVAGTPREAIRERVEELLSLVGLSDKAQAYPSQLSGGQKQRVGIARALAPRPRVLLSDEATSALDPETTRSVLGLLRDINQKLGVTLLLITHQMDVVKAICDSVSVLERGRLVEQGKVTELLAHPSTRLHQLCFPAFAAPTDAPSGRRVALTLAGEHARRPLLGTLARQFDVDALLVEGAMERVGNTRVGRLLVDLQGSADAVSQALAYLREQGLTLEEAANG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LANA2_LACLL
Sequence: MKEKNMKKNDTIELQLGKYLEDDMIELAEGDESHGGTTPATPAISILSAYISTNTCPTTKCTRAC
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.  When present individually lacticin 3147 A2 exhibits weak activity towards L. lactis strain AM2 and L. lactis strain HP, and no activity towards L. lactis strain IFPL359, but when combined with lacticin 3147 A1 it displays strong activity towards all three strains.
What are the official names of this protein?
Lantibiotic lacticin 3147 A2.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_GRABC
Sequence: MANVAVIGAQWGDEGKGKVVDWLASRADVVVRFQGGHNAGHTLVVGDQTYKLSLLPSGLVRGKLGIIGNGVVVDPEALLSEIARVSAQGLAVGPETLRIADNATLILPLHGAIDRAREQARGDSKIGTTGRGIGPAYEDKVARRAIRIADLAEPETLSAKLDELLLHHNTLLAGLGAETFEKQALLDQLLALAPKILPYAEPVWERLDEIKRAGQRILFEGAQAVMLDVDHGTYPFVTSSNTIAATAAGGSGMGPSAVDFVLGIAKAYSTRVGSGPFPTELFDETGELLGDRGHEFGTVTGRRRRCGWFDAVLVRQAVKVGGIQGLALTKLDVLDGLPELKICTGYQINGETFRRLPASPAAQAAAKPVYESMEGWSGSTQGARSWADLPAQAIKYVRRIEELTEVPVTLLSTSPDRDDTILVKDPFEG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_MOOTA
Sequence: MISTNDFRTGLTIEVDGDVYTVVEFMHVKPGKGSAFVRTKLKNRRTGAVIERTFRAGEKVNRAHVERREMQYLYNDGDNYYFMDTETFEQLSLRKEQLEDAIKYLKDNMNIFVLTYNGETIGIELPNSVELKVVETEPGIKGDTATGGTKNAVLETGAVIQVPLFIETGDVVRIDTRTGEYIERA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXC8_CHICK
Sequence: MSSYFVNPLFSKYKGGESLEPTYYDCRFPQSVSRSHALVYGPGTTAPTFQHPSHHVQEFFHHGTSSISNSGYQQNPCALACHGDASKFYGYEALPRQSLYGAQQETTVVQYPDCKSSSNSNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKTEEEGNEEEEKEEEEKEESKD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C8, cHoxc-8.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFKA_THEVB
Sequence: MSSSRKRLGVFTSGGDCPGLNTAIRAIVAHATLSYGWEVLGILHATQGLIERKAIPLNAEGLGGMDVLLNMGGTILGAINKGDTLGHADEVIAGYYELGLDALIAICGDGSLRILHQLAQKGNWNFLAIPKTIDNDVALTDRAIGFDTAVNTVVEALNRITSTAASHDRVFVVEVMGRTAGHLALYSGIAGGADIILIPEIPYSIEGICQHLQKLRDRWGRQFALIVVAEGSKQLEEDANHPRHCSIGQYIADKIAQHSPIPIELRVSVLGHIQRGGAPMAMDRLLAAGMGNTAVDLAAQGTFGRMVAWQAGQVVTVPIADVVAKCPRHVDPNSFLIRTAQGLGIYVGDKPMLPYVDPTLCRDQVICAI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.