PharMolix/UniProtQA huggingface dataset:
Protein: ERG8_SCHPO
Sequence: MKVTCSAPGKVLIAGGYIVLDPQYSGLVIGLTAKGYASTTTLDDKCGTVRVKSPQFINAEWLYNIDWTVSPIRVHQIYENCELEKNPNPFVQLALFYVINYFFSTGRQPLCWQDLQVTLQVDNAYYHQPQLKPDQTSYPKFNFLNCTLGQVHKTGLGSSAAMITSLIGSLFLSLRRLTDDTGDKSLKIDDSTKVIVHNLAQIAHCSAQGKVGSGFDVGAATWGSCIYRRFDPKLIEQLLVPYDEQIKNINFSTELRKIVSKKWSDVVPFQLPATYCLLMGDVAGGSSTPGMVKKVQQWQKENPEESKNCFDDLYSRVLSIKNCFLSSESLDSELQSQFRSIRRILQRITVEAKVDIEPLKQTNILDNIEQLPGVIGVGVPGAGGFDAQFCLAINHTEIIENVIKTWKDDGVVPMDVSPAFDGLAVE
What is the function of this protein?
Phosphomevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  Erg8 converts 5-phosphomevalonate to 5-diphosphomevalonate (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8.  The diphosphomevalonate decarboxylase mvd1 then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase fps1 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Phosphomevalonate kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: GLGB_MYCSS
Sequence: MAKTKGLPKDTAVTPSPHLRPHTADLNRLLAGEHHDPHSILGAHEYDDHTVIRAYRPHATEVAAVVGGERHVFTHLEAGVFAVTLPFTGLIDYRLEVGYDHGGDQPHIHHTADAYRFLPTLGEMDLHLFSEGRHERLWEVLGAHPRTFETPDGVVEGVSFAVWAPNANGVQLIGDFNHWDGNEAQLRVLGSTGVWELFWPDFPVDGLYKFRIHGADGVVSERADPMAFATEVPPQTASRVTTSSYTWNDDAWMTQRAAQNPVFEPMSTLEVHLMSWRPGLSYVELADQLTEYIVEHGFTHVEMLPVAEHPFGGSWGYQVTSYYAPTSRLGTPDEFRYLVDRLHQAGIGVIVDWVPAHFPKDAWALGRFDGTALYEHADPRRGEQLDWGTYVFDFGRAEVRNFLVANALYWLQEFHVDGLRVDAVASMLYLDYSRPEGGWTPNIYGGRENLEAVQFLQEMNATVHKASPGIVTIAEESTSWPGVTRPTNLGGLGFSMKWNMGWMNDTLAFISRDPIHRSYHHHEMTFSMLYAFSENYVLPISHDEVVHGKGTLWGRMLGDDHRKAAGVRQLLAYQWAHPGKQLLFQGQEFGQRAEWSEERGVDWYQLDENSYSGGILRMISDMNGIYTSHRALWSHDTSPEGYSWIDANDSTNNVLSFLRYGDDGSVLACVFNFSGSEHSQYRLGLPHAGTWREVLNTDAADYNGAGIGNYGAVQATDEPWHGRPASAVMVLPPLSALWFEPVAAEAPVVQEPPTAPPLS
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RS11_CELJU
Sequence: MAKPGNKTATKKKVKKTVIDGVAHIHASFNNTIVTITDRQGNALAWATSGGSGFRGSRKSTPFAAQVAAERAGEAAKEYGLKNLDVEVKGPGPGRESAVRALNNVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SELU_AZOVD
Sequence: MRADTADYPQLFLEDVPMMDTRAPVEFAGGAFPNVLNLPLMTDSERQKVGTCYKQHGQRAAIELGHRLVSGRTKELRIQAWADFARAHPEGYLYCFRGGLRSQIVQQWLRDEAGIDYPRVTGGYKAMRNFLLDTTRQATAQCAFVLVGGLTGTGKTEVIAALGNALDLEGHANHRGSSFGKRATPQPAQIDFENRLAIDILRKRAAGVGRFVLEDESRLVGSCSLPLELHQGMQRYPLVWLEDSFEGRVERILRDYVVDLCAEFVAVEGPQAGFAAFAARLTQSLANIVKRLGGERYQRLSTLMARALAEQEAGRGVALHRDWIVGLLREYYDPMYAYQRESKAERIVFSGDREAVLAYLRECAAGAVDG
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: VKT7_DEMVE
Sequence: MSSGGLLLLLGLLTLWAELTPVSSKDRPEICKLPKEPGPCRSYLLYFYYNSVEHKCQTFHYGGCEGNENRFHTIEECKSTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor vestiginin-7.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUCS_MYCBO
Sequence: MSRVRLVIAQCTVDYIGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWLTEESGGQAPVWVVENKAGEQLRITIEGIEHDSSHELGVDPGLVKDGVEAHLQALLAEHIQLLGEGYTLVRREYMTAIGPVDLLCRDERGGSVAVEIKRRGEIDGVEQLTRYLELLNRDSVLAPVKGVFAAQQIKPQARILATDRGIRCLTLDYDTMRGMDSGEYRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_YERPS
Sequence: MRIRHRLCRFRKSKHVRHQRFRSRIFHRDSAVAKEMKKPFVVVLTGAGISAESGIRTFRADDGLWEDHRVEDVATPEGYRRDPELVQRFYNERRRQLQQPDIAPNAAHFALADLEAVLGDNLVLITQNIDNLHERAGSKRVIHMHGELLKVRCTQSGQVLDWQGDLSADERCHCCQFPSPLRPHIVWFGEMPMGMDDIYQALAEADFFISIGTSGHVYPAAGFVHESHLHGAHTVELNLEPSQVESQFDEKHYGLASKVVPEYIREFLTTCGENRQGD
What is the function of this protein?
NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins.  Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPC5_COPCM
Sequence: MYVAGVSFQQDTMPVLVHRKLEVNHKPPAVKEIVKHLIQVLNPKLHLYLFPVRRNPGYLKFTISLHLFLAHINCIHYSTSKLPSSSTLSSAKRSSISRNSSSSSLSDITMNSSESLPITLSLLSSNIACFLAFSFAFCLAV
What are the official names of this protein?
Allergen Cop c 5.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FGF9_HUMAN
Sequence: MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration.  May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
What are the official names of this protein?
Fibroblast growth factor 9, FGF-9, Glia-activating factor, GAF, Heparin-binding growth factor 9, HBGF-9.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3066_GEOKA
Sequence: MGQNGALQPIQLVIITGMSGAGKTVAIQSFEDLGFFCIDNLPPTLLPKFLELVKESGNKMNKVALVMDLRSRDFFDHLFAALDELAEQAWVIPQVLFLDAQDSTLVARYKETRRTHPLAPNEPPLEGIRLERKLLEELKGRAQIIYDTTGLKPRELREKIIRQFSSHAQSGFTINVMSFGFKYGIPIDADLVFDVRFLPNPHYIEHMRPKTGLDDDVSSYVLKWGETQKFLEKLIDLLSFMLPYYQREGKSQLVIAIGCTGGQHRSVALAEYIARHFSDDYKTVVSHRDMERRKDIHR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein GK3066.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ALLS_DIPPU
Sequence: MSGPRTCFCLPSALVLVLLSLSTSALGTAPEPSGVHEESPAGGGTDLLPHPEDLSASDNPDLEFVKRLYDFGLGKRAYSYVSEYKRLPVYNFGLGKRSKMYGFGLGKRDGRMYSFGLGKRDYDYYGEEDEDDQQAIGDEDIEESDVGDLMDKRDRLYSFGLGKRARPYSFGLGKRAPSGAQRLYGFGLGKRGGSLYSFGLGKRGDGRLYAFGLGKRPVNSGRSSGSRFNFGLGKRSDDIDFRELEEKFAEDKRYPQEHRFSFGLGKREVEPSELEAVRNEEKDNSSVHDKKNNTNDMHSGERIKRSLHYPFGIRKLESSYDLNSASSLNSEENDDITPEEFSRMVRRPFNFGLGKRIPMYDFGIGKRSER
What is the function of this protein?
Neuropeptide inhibitors of juvenile hormone synthesis and gut muscle contraction.
What are the official names of this protein?
Allatostatins.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VIRB4_AGRFC
Sequence: MLGASGTTERSGEVYLPYVGHVSDHIVLLEDGSIMTMAHVSGMAFELEDAEMRNARCRAFNTLLRNIADDHVSIYAHLVRHDDVPPSPARHFRSAFSASLSEAFEERVLSGKLLRNDHFLTLIVSPRAALGKVRRRFTKRYRQKENDLTAQTRNLEDLWHLVAGALEAYGLRRLGIREKQDVLFTEVGEALRLIMTGRFTPVPVVSGSLGASIYTDRVICGKRGLEIRTPKDSYVGSIYSFREYPATTRPGMLNVLLSLDFPLVLTQSFSFLTRSQAHSKLSLKSSQMLSSGDKAVTQISKLSEAEDALASNEFVLGAHHVSLCIYANDLNNLADRGARARTRLADAGAVVVQEGIGMEAAYWSQLPGNYKWRTRPGAITSRNFAGLVSFENFPEGSGSGHWGNAIARFRTNGGTPFDYIPHEHDVGMTAIFGPIGRGKTTLMTFILAMLEQSMVDRAGAVVLFDKDRGSELLVRATGGTYLALRRGAPSGLAPLRGLENTAASHDFLREWIVALIESDGRGGISPEENRRLVRGIHRQLSFDPHMRSIAGLREFLLHGPAEGAGARLQRWCRGNALGWAFDGELDEVKLDPSITGFDMTHLLEYEEVCAAAAAYLLHRIGAMVDGRRFVMSCDEFRAYLLNPKFAAVVDKFLLTVRKNNGMLILATQQPEHVLESQLGASLVAQCMTKIFYPSPTADRSAYIDGLKCTEKEFQAIREDMAVGSRKFLLKRESGSVVCEFDLREMREYVAVLSGRANTVRFADQLRKVQGDNPSAWLSEFMARYHEAKD
What is the function of this protein?
A possible function of virB4 might be to provide the energy, via hydrolysis of ATP, for translocation of virulence proteins of the transfer of a T-DNA-protein complex across the agrobacterium membrane.
What are the official names of this protein?
Protein virB4.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
Protein: ATPF_CLOPD
Sequence: MQFASFISLDWGVVFQIVNTIVMYLILKKLLFKPVTKFMNDRQESIANSIKEAEETKKEAYALKAEYEAKINASKEEGQEIIKEASRKAEMRADEIIKNAQNEANRLMEKAHIEIEREKQKVVNELKDEISNIAILAASKVIEADIDKNKHEKLISDFIKEVGEATWQN
What is the function of this protein?
In this organism this enzyme may function as an ATP-driven Na(+) ion pump to generate a Na(+) ion electrochemical gradient rather than as an ATP synthase.
What are the official names of this protein?
ATP synthase subunit b, sodium ion specific, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PLSX_SHESA
Sequence: MTSLTLALDAMGGDHGPHVTVPAALRALKSHSSLKIILVGDKTEIDVYLRQAEQPLLSRIEVIHTDEVVSMSDRPVHALRTRKNSSMRLSIELVRDGRAAACVSAGNTGALMAMAKVLLKTLPGVDRPALVSCLPSVTQKPVYLLDLGANISCDSETLFQFAVMGSVLCEAVDKKSRPKVALLNVGTEEIKGNDQVQQAAQILQNTDQINYTGFIEGDEIYLGNVDVIVCDGFVGNITLKTSEGIAKLLVHQLKRGLTQGFFVRFLAKLIAPRIQAVLSQMNPDHYNGASLIGLRGIVVKSHGNADETAYLQAISLAVTEAQRRLPEMIKDRLESILLDINN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: IL8_BOVIN
Sequence: MTSKLAVALLAAFLLSAALCEAAVLSRMSTELRCQCIKTHSTPFHPKFIKELRVIESGPHCENSEIIVKLTNGNEVCLNPKEKWVQKVVQVFVKRAEKQDP
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: P2Y13_RAT
Sequence: MLGTVNTTGMQGFNKSERCPRDTRMTQLLFPVLYTVVFFTGVLLNTLALWVFIHIPSNSTFIIYLKNTLVADLIMTLMLPFKILSDSRLAPWQLRGFVCTFSSVVFYETMYVGIMMLGLIAFDRFLKIVVPFRKTFVKKTAFAKIVSISIWLLMFLISLPNMILNKEATASTVKKCASLKSPLGLLWHQVVSHTCQFIFWTVFILMLLFYTVIAKKVYDSYRKFKSRDSKHKRLEAKVFIVMAVFFVCFAPFHFVRVPYTHSQTTNKTDCRLENQLFLAKESTLFLATTNICMDPLIYIILCKKFTRKVPCMRWRTKTAASSDEHHSSQTDNITLS
What is the function of this protein?
Receptor for ADP.  Coupled to G(i)-proteins.  May play a role in hematopoiesis and the immune system.
What are the official names of this protein?
P2Y purinoceptor 13, P2Y13.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_DICDI
Sequence: MKTVTLATCNLNQWAMDFKGNLERIIESINIAKSKGAKYRLGPELEICGYGCEDHFLEQDTMLHCWQSLAVILKDPELTKDILVDVGMPVLHKDVRYNCRVILLNQKIYLIQPKKAMAMDGNYREGRWFTPWIKPRVVETFYLPRIISQITGQDECQIGDAIISTLDTAISSETCEELFTPNSPHIQMGLDGVEIFTNGSGSHHQLRKLDTRVDLIRSATSKSGGIYLYSNQQGCDGSRLYYDGSCMIMINGDCVSQGSQFSLVDIEVITATVDLEDVRSVRASFMARCAQANLTKEFPRVRCPIQLTHIDYCHPPDRVIHINYNTPAEEIGFGPACWLWDYLRRSGLSGYFLPLSGGADSAATAAIIGIMCQLVILDVSKGNKQVLKDAQRITNSPEDYIPTDSREFASRLFFTAYLGSKNSSKETRDRAMEIAKDIGSVHKEVDIDDISQSFNDAFSQITKKQPQFRAHGGTPRENLALQNVQARTRMVLSYHLASLLLWEQGRPGSLLVLGSANCDESLRGYMTKYDCSSADINPIGGMSKIDLRSFIEWAGKFRDMKSILSVLTATPTAELEPITENYTQSDEIDMGMTYEELSIFGKLRKVNRCGPVSMFERLVADWAHLEPSVVAEKVKRFFYYYAINRHKLTTLTPSYHAEGYSPDDNRYDHRQFLYNSKWDVQFETIDKIVLRLSQRPQLKNTVNCPNQASLTQQ
What are the official names of this protein?
Glutamine-dependent NAD(+) synthetase, NAD(+) synthase [glutamine-hydrolyzing].
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD synthetase family.
Protein: METC_LACLA
Sequence: MTSIKTKVIHGGISTDKTTGAVSVPIYQTSTYKQNGLGQPKEYEYSRSGNPTRHALEELIADLEGGVQGFAFSSGLAGIHAVLSLFSAGDHIILADDVYGGTFRLMDKVLTKTGIIYDLVDLSNLDDLKAAFKEETKAIYFETPSNPLLKVLDIKEISAIAKAHDALTLVDNTFATPYLQQPIALGADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQRGIKTLALRMEAHSANAQKIAEFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELTDENAVKDFVENLSYFTLAESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEAIEDLLTDIKEALEKK
What is the function of this protein?
The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development.  Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha, gamma elimination.  With methionine as a substrate, it produces volatile sulfur compounds which are important for flavor formation in Gouda cheese.
What are the official names of this protein?
Cystathionine beta-lyase, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_STACT
Sequence: MARSIKKGPFVDNHLMKKVEAQEGNQKKTVIKTWSRRSTIFPNFIGITFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHAVDDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CLPX_RHOPB
Sequence: MSKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQSHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFSGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLKKILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVEGTARPLYIYADRSDRTAESSASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: VPS29_YEAST
Sequence: MLLLALSDAHIPDRATDLPVKFKKLLSVPDKISQVALLGNSTKSYDFLKFVNQISNNITIVRGEFDNGHLPSTKKDKASDNSRPMEEIPMNSIIRQGALKIGCCSGYTVVPKNDPLSLLALARQLDVDILLWGGTHNVEAYTLEGKFFVNPGSCTGAFNTDWPIVFDVEDSDEAVTSEVDKPTKENQSEDDDAKGGSTGKEQPGSYTPKEGTAGERENENESNVKPENQFKEDEVDMSDSDINGSNSPSFCLLDIQGNTCTLYIYLYVNGEVKVDKVVYEKE
What is the function of this protein?
Plays a role in vesicular protein sorting.  Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor VPS10.  Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.  The VPS29-VPS26-VPS35 subcomplex may be involved in cargo selection.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 29, Carboxypeptidase Y-deficient protein 11, Vesicle protein sorting 29.
What is the protein family that this protein belongs to?
Belongs to the VPS29 family.
Protein: OIG4_CAEEL
Sequence: MSFRLWGRCIFFFCFLLEAIDSRGGRRGGKGKGKSNLQFAQVAEFSLVQTVLSDNRSAQIITGSHFSQTYRLGYKLLIICKARGDPRPTIKWYKEGAEIQPKASIHYYEKPIENDTIWSKLEVDPATMGDQGVYACVANNPHGVMAKNFKAEYTY
What is the function of this protein?
Required for the localization of acetylcholine receptors at neuromuscular junctions and for subsequently controlling the response evoked by receptor stimulation.
What are the official names of this protein?
Immunoglobulin domain-containing protein oig-4.
What are the subcellular locations of this protein?
Synapse. Secreted. Note=Secreted by body wall cells. Co- localizes with and requires acetylcholine receptors for localization at neuromuscular junctions.
Protein: KN7K_ARATH
Sequence: MASRQGSKSRKAGLKGADSTASSTTSSSKLYQETSIDGHSSPASSSAQSKQQFFSPDPLPQTAQRSKENVTVTVRFRPLSPREIRQGEEVAWYADGETIVRNEHNPTIAYAYDRVFGPTTTTRNVYDIAAHHVVNGAMEGINGTIFAYGVTSSGKTHTMHGDQRSPGIIPLAVKDAFSIIQETPNREFLLRISYMEIYNEVVNDLLNPAGHNLRIREDKQGTFVEGIKEEVVLSPAHALSLIAAGEEQRHVGSTNFNLLSSRSHTIFTLTIESSPLGDKSKGEAVHLSQLNLVDLAGSESSKVETSGVRRKEGSYINKSLLTLGTVISKLTDVRASHVPYRDSKLTRILQSSLSGHDRVSLICTVTPASSSSEETHNTLKFAHRAKHIEIQAEQNKIIDEKSLIKKYQREIRQLKEELEQLKQEIVPVPQLKDIGADDIVLLKQKLEDGQVKLQSRLEEEEEAKAALLSRIQRLTKLILVSTKNPQASRLPHRFNPRRRHSFGEEELAYLPYKRRDMMDDEQLDLYVSVEGNHEIRDNAYREEKKTRKHGLLNWLKPKKRDHSSSASDQSSVVKSNSTPSTPQGGGSHLHTESRLSEGSPLMEQLSEPREDREALEDSSHEMEIPETSNKMSDELDLLREQKKILSEEAALQLSSLKRMSDEAAKSPQNEEINEEIKVLNDDIKAKNDQIATLERQIMDFVMTSHEALDKSDIMQAVAELRDQLNEKSFELEVKAADNRIIQQTLNEKTCECEVLQEEVANLKQQLSEALELAQGTKIKELKQDAKELSESKEQLELRNRKLAEESSYAKGLASAAAVELKALSEEVAKLMNQNERLAAELATQKSPIAQRNKTGTTTNVRNNGRRESLAKRQEHDSPSMELKRELRMSKERELSYEAALGEKEQREAELERILEETKQREAYLENELANMWVLVSKLRRSQGADSEISDSISETRQTEQTEGSF
What are the official names of this protein?
Kinesin-like protein KIN-7K, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURA_COXBU
Sequence: MDKLIIVGGVPLNGSIRISGAKNAVLPILAATLLIEEPVILSNIPHLNDVTTMIELLGRMGAQITIDERMSIEVDCSQIQNVHASYELVKTMRASILVLGPLLSRFGKAEVSLPGGCAIGSRPVDVHIDGMRALGADIELVDGFIHATVEGRLKGAELNLGKITVTGTENLIMAATLAEGQTIIHNAACEPEVQDLANFLNKMGARISGAGTDTIVIDGVDRLSGGSYSILPDRIEAGTYLVAAAMTRGHVRIRDVFPKTLGAVLEKLHEAGARVKIGENWVDLDMQGRRAKAVDIVTAPYPEMPTDMQAQFMALNVVAEGQAVITETVFENRFMHVHELQRMGADIKLQGSKALIRGKEKLTGAPVMATDLRASAGLVLAGLMARGNTIVDRIYHIDRGYECIEEKLAQLGAEIRRVSSHVYAARYAAQKRWL
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_GEOSE
Sequence: MSKDFIINEQIRAREVRLIDQNGDQLGIKSKQEALEIAARRNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEARKKQKVINVKEVRLSPTIEEHDFNTKLRNARKFLEKGDKVKATIRFKGRAITHKEIGQRVLDRLSEACADIAVVETAPKMDGRNMFLVLAPKNDNK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_SHEB9
Sequence: MNPRRKKRLTLAVALIGGVAAITSLLLYALNSNLNLFYTPSEIVHGKTDTGVKPEIGQRIRVGGMVTVGSMVRDPKSLHVQFAVHDSLGGEVLVTYDDLLPDLFREGQGIVAQGVLSADGKLEATEVLAKHDENYMPPEVAEAMGQKHEKLDYSQQKAPDTK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: UL38_HHV6U
Sequence: MAFTGDELARMLQFKDKMISSAGLALKFEKVVQEAMASGIVLQHITCIKVRICDNSDILSDRQLRSLLINGLYPFEGRMSMFGVTEEWEGASAAPERQVVFLLSSTGQVLGYEDGVVFYLSPTFSDFWTTAMEFSCQNAILSNFIAQKSRDEYIDQFQKYFTRMRHTPIFLTGVLPRRFQKVESSACVEEDARASMRPIQCDSFGVKDTFCRPTEELLQPSANKDVGGKVCMSLSCREDNSARHCTIYGLTETRGIKIMFSRHTQTDRSEVMCNAATQTGDVVDNSSETLFLGKNLVHQSILETEVKTTAKNTFDVSNPRIDSVYDTTVFGAMATDDVGCENVQGGASLAQEKPLKGYCITATPSECKPNIHWLKSPEKTVQESAAVLR
What is the function of this protein?
Plays a role in the inhibition of host apoptosis to facilitate efficient viral replication.  Promotes stabilization and inactivation of host TP53 through interaction with host MDM2.
What are the official names of this protein?
Apoptosis inhibitor U19.
What is the protein family that this protein belongs to?
Belongs to the beta-herpesvirinae UL38 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=localized in the host nucleus at early times postinfection and then increases in both nuclear and cytoplasmic compartments during the course of infection.