PharMolix/UniProtQA huggingface dataset:
Protein: ACTA_RAT
Sequence: MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, aortic smooth muscle, Alpha-actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AGGL_SCLSC
Sequence: MGFKGVGTYEIVPYQAPSLNLNAWEGKLEPGAVVRTYTRGDKPSDNAKWQVALVAGSGDSAEYLIINVHSGYFLTATKENHIVSTPQISPTDPSARWTIKPATTHQYEVFTINNKVSELGQLTVKDYSTHSGADVLSASAKTADNQKWYFDAK
What is the function of this protein?
Lectin that primarily recognizes glycans with a non-reducing terminal N-acetylgalactosamine (GalNAc), with a preference for the alpha- over the beta-anomer.  Can also bind non-reducing terminal galactose (Gal) residues but with a lower affinity.  Strongly interacts with glycolipid type glycans with terminal non-reducing Gal or GalNAc but fails to bind sialylated or fucosylated forms of the same glycans.  Strongly interacts with galactosylated N-glycans, displaying highest affinity for alpha-1-3 branched mono-antennary N-glycans but also binding to multi-antennary glycans.
What are the official names of this protein?
Agglutinin, SSA.
Protein: NU4M_CARSF
Sequence: SFIGATTLMIAHGLTSSLLFCLANTNYERVHSRTMALARGLQTLLPLAATWWLLASLTNLALPPTINLIGELSVMMAAFSWSHLTIILVGLNTLITALYSLYMLIMTQRGKYTYHINNIMPPFTRENTLMIMHLFPLILLSTNPKLIMGTMYCKYSLNKTLDCESNN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: K1958_MOUSE
Sequence: MEDCLHTSSENLSKLVSWAHSHGTICSLIPNLKHLLSEGSHGNLTAMWGCSAGHAYHWPLTATCRAGSQERVCFQDNRSFNSDSPSIIGVPSETQTSPVERYPGRPVKAKLDCNRTRDSCDFSYCSEPSELDEAVEEYEDENTLFDMVCESSVTDEDSDFEPQTQRPQSIARKRPGIVPSSIHSSSQGQMVDECSNDVIIKKIKQEIPEDYYIVANAELTGGVDGPALSLTQMAKPKPQTHAGPSCVGSAKLIPHVTSAINTELDPHILSASPSVISRPIIPKTARVSLASPNRGPPGAHGTAHQVTMQMPVSTSHPNKQISIPLSALQLPGQDEQVASEEFLPHLPSQVSSCEVALSPSVNTEPEVSSSQQQPPAAPTITTEATAQCIPAYSTKLNKFPVFNINDDLNGLCTSAVSPNTTKATRYALNVWRYWCMTNGLKDHTDITKIPAVKLNELLENFYVTVKKSDGSDFLATSLHAIRRGLDRILKNAGVGFSITSSTFSSSTKKLKEKLWVLSKAGMSGARSRNIVYFSLSDEEEMWQAGCLGDDSPITLLSTVVKYNSQYLNMRTLQEHADLMYGDIELLKDPQNQPYFARTDSVKRESRSGSTRVCHGKIYHEHSRGHKQCPYCLLYKYMYIHRPPTQMEAKSPFYLTARKEATDMGSVWYEEQRMGLRSLRGIVPNLARKVKLENCENFTFVSFTQVSRRLGSHSCCQ
What are the official names of this protein?
Uncharacterized protein KIAA1958 homolog.
Protein: RL28_VEREI
Sequence: MARVCDVTGKKPMVGNNVSHANNKTRRRFLPNLQYRRFWVETENRWVRLRVSSAALRLIDKNGIDAVLADLRARGQA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: BFAT_VARPD
Sequence: MTHAAIDQALADAYRRFTDANPASQRQFEAQARYMPGANSRSVLFYAPFPLTIARGEGAALWDADGHRYADFIAEYTAGVYGHSAPEIRDAVIEAMQGGINLTGHNLLEGRLARLICERFPQIEQLRFTNSGTEANLMALTAALHFTGRRKIVVFSGGYHGGVLGFGARPSPTTVPFDFLVLPYNDAQTARAQIERHGPEIAVVLVEPMQGASGCIPGQPDFLQALRESATQVGALLVFDEVMTSRLAPHGLANKLGIRSDLTTLGKYIGGGMSFGAFGGRADVMALFDPRTGPLAHSGTFNNNVMTMAAGYAGLTKLFTPEAAGALAERGEALRARLNALCANEGVAMQFTGIGSLMNAHFVQGDVRSSEDLAAVDGRLRQLLFFHLLNEDIYSSPRGFVVLSLPLTDADIDRYVAAIGSFIGGHGALLPRAN
What is the function of this protein?
Aminotransferase that acts exclusively on beta-amino acids and exhibits a broad substrate range in vitro, accepting meta-, para- and, to a lesser extent, ortho-substituted beta-phenylalanine derivatives as amino donors, and 2-oxoglutarate or pyruvate as amino acceptors.  Is highly enantioselective toward (S)-beta-phenylalanine (is not active with (R)-beta-phenylalanine) and derivatives with different substituents on the phenyl ring, allowing the kinetic resolution of various racemic beta-amino acids to yield (R)-beta-amino acids with >95% enantiomeric excess (ee).  Highly prefers aromatic beta-amino acids over aliphatic beta-amino acids; cannot use beta-alanine or beta-glutamate as substrate.  Is likely involved in the beta-phenylalanine degradation pathway that allows V. paradoxus strain CBF3 to use beta-phenylalanine as a sole nitrogen source.
What are the official names of this protein?
Beta-phenylalanine transaminase, Aromatic beta-amino acid aminotransferase, Beta-phenylalanine aminotransferase, VpAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: ANMK_SALRD
Sequence: MDALLALHRRSRRTVVGLMSGTSLDGVDAALVQLDGSGPDLTMNPEAFVHIPYPTALRDLIRTNTDPASSSVQDVTRLDARLAETYAAAVDRVAAEADVDRGTVDLVGAHGQTVCHLPEPADCAGKDVRATLQLGNPSTLATRLGVPVVGNFRAADLALGGQGAPLVPYFDRVAFTAPDEARGLLNLGGIANLTVLPAGAAPDDVRAFDTGPANMVIDALAARLFDAPHDPDGRHANAGTPDHDLLADLLEGEYFRREPPKSTGRNDFGPDYVDRLLGAAQSRTLSPEDTMATATLLTAASVYQAYAQYVRPEQAIDELIVSGGGVHNDTLLRMLEEAFTPIPVRPTSDYGVAPDAKEALCFAVLAHEAVNGTPTNLPSVTGASARTPLGSLSVPGP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: QUEF_ANADF
Sequence: MPTKPARDLQTFPNPKPDRPYEIAMECPEFTCVCPVTGQPDFATIRLRYVPAERCVELKSLKLYLWSFRDEGTFHEAVTNRICDDIVQAIAPRWIEVVGDFAVRGGIHTVVTARHGERPAGV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRS1_MOUSE
Sequence: MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKAHHDGAGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPNGHYILSRGGNGHRYIPGANLGTSPALPGDEAAGAADLDNRFRKRTHSAGTSPTISHQKTPSQSSVASIEEYTEMMPAAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHHLERRGGHHRPDTSNLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGSCSPDIGGGSSSSSSISAAPSGSSYGKPWTNGVGGHHTHALPHAKPPVESGGGKLLPCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSSSSGRLRYTATAEDSSSSTSSDSLGGGYCGARPESSLTHPHHHVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQQQSSLHPPEPKSPGEYVNIEFGSGQPGYLAGPATSRSSPSVRCPPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGVELGRIGPAPPGSATVCRPTRSVPNSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKASLPRPTGAAPPPSSTASSSASVTPQGATAEQATHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKVIRADTQGCRRRHSSETFSAPTRAGNTVPFGAGAAVGGSGGGGGGGSEDVKRHSSASFENVWLRPGDLGGVSKESAPVCGAAGGLEKSLNYIDLDLAKEHSQDCPSQQQSLPPPPPHQPLGSNEGNSPRRSSEDLSNYASISFQKQPEDRQ
What is the function of this protein?
May mediate the control of various cellular processes by insulin.  When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.  Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
What are the official names of this protein?
Insulin receptor substrate 1, IRS-1.
Protein: PUR7_CHLPB
Sequence: MNKTELLHEGKAKKVFLTDNKDLVIQEFKDDATAFNNKKKGTIGNKGVVNNAISCKLFTYLAEHGVSTHFVEKLSDRDMLCKRLDIILVEVVVRNTAAGSLVRRYGFEEGFRLEDPIIELYLKDDDLDDPLMNESHAVALGLANYEELELLKEQAATINTLLKTFFAGRKLNLVDFKLEFGRHNGEILLGDEISPDTCRFWDLDTGEKMDKDRFRFDLGGVEDAYTEVQHRVLDLP
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FPG_NITMU
Sequence: MPELPEVEVVRRGIASGLEGRKIAGLTVRNPNLRWPVPELERTLCGLEIRTVTRRGKYLLLDCGAGTLILHLGMSGSLRLLALAANIAPQKHDHIDLLLDKGMVLRFRDPRRFGAVLWTTGNATDHPLLSHLGPEPLTEAFDGKLLYSKTRNRSASIKEVLMNSRIVVGVGNIYANEALFLAGIDPANAAGRIGARRCAGLAQAIKETLGRAIEAGGSSLRDFVGSDGNPGYFQQQYWVYSRTGQPCRKCGTNIEQIRQGQRSSFYCPRCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GLNE_STRMK
Sequence: MTLAPADLPVSLQPLVDRALARLAQVLTEPIPADLLPLLTRLAVASDFALDTLVRQPALLAQLAAPGCPPIPAPVLDPLQPSDWPAQLRRWRAAMSTRLIWRDLAGLDDVAQTLAGATTLAEDCLRLALEALQQEFAQRHGVIADDQGTPQQLVVFGLGKLGGGELNFSSDIDLVYAYPHGGESDGPRALAAEEYFARLGQRLAKLLDETTVDGFSHRVDLRLRPFGSAGRVALSFAAMDQYFQREGRDWERYAWLKARAVAGDIAAGEAWLQTLRPFVYRRYLDFTALDGLREMKAAITAEVARRELHEDIKRGAGGIREIEFLCQALQLIRGGREPALRERRLLVALDALVAAGQIAPEDGSALREAYLFLRRLENRLQMLRDAQTHVLPSDALDRERIAVGLGYADWNVLRAALAEQQQRVSTEFAALLAPRKGQAAPDALANYWRSLPEGSNAPLLAEAGFLDANGADQSLRDFAQGTGVKSLSDAARARLDRVLPALLHAATRSPQPDAALKRVLGLLQAVLRRTSYLALLDEQPSALARLVDVLARSALLAERLAAYPLLLDELLDVRVSGPMPDAAGMLAECQQVLAVEDPESALRWLNETRLALSFRMAMATLDGRQGAVDSTRQLAELAQAVVVTVLAMAEADMHAAHGGIPGGRFAIIGYGSLGGLELGFGSDLDLVFLHDNPAGVDASDGARPLEPGRWYARLAQKVMALLGAVTAAGRLYDIDVRLRPDGGKGSLVSSLASYTEYQRERAWTWEHQALVRARGVAGDASLLADFEQVRAQTLGRERDTGVLYADVLKMRGRMRTELDRSDAARLDLKQGAGGVVDLEFLLQTGVLARSAQHAALLQPRDTPSLIDALAVAGFLPDATAQALHGAHATLLDVGLACTLDRRPRLAPTTPAIEEACAAITAACRAAELPFA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: DNAK_WOLTR
Sequence: MGRAIGIDLGTTNSCVAIQGKIIENKEGARTTPSVVAFTSSGERLIGAPAKRQATTNASNTFFATKRLIGRQYGDPEMKDLNVPYKVFAAKNGDAWIKTTDGKEYSPSQIGAFILQNLKEAAEAYLGEEVKDAVITVPAYFNDSQRQATKDAGKIAGLNVLRIVNEPTAAALAYGLDKKHGHTIVVYDLGGGTFDVSILEIGDGVFEVKATNGDTHLGGEDFDNAIVSYLLDEFKKSNGIGLKNDPMAMQRIKEAAEKAKIELSSAMETEINLPFITADANGPKHLNMKLTRAKLESLVNDLIERTMTPCKKALEDTGLSANQIGEVVLVGGMTRMPRVIEKVKEFFGKDPHRGVNPDEVVAIGAAIQAGIVQGDVRDVLLLDVTPLSLGIETLGGVFTPLIERNTTIPTKKSQVFSTAEDNQTAVTIKVHQGERKLAVDNKLLGQFSLEGIPPAPRGIPQIEVTFDIDANGIVHVSAKDKATGKEQKIRIQSSGGLSESEINRMIREAEEKAQEDEKRKKFVEVKNQADSLVHSTEKSLKEYGDKVSPEDKSAIENAVNELKEASKSDNIDDVDSIQQKITNLSQLSMKLGETIYKESQQQQGKESSAGSSTTNEEEKVVDSDYQDIDNKEENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYFA_PYRAB
Sequence: MTLGYNEKLVLLTIAKLEKASVEEIVKETRLDQVAVMRAILTLEKEGLIKLHERKEKIIVLTDIGKEYSKIGLPEIRALRVLREKKKAYLDELKDVLREDELKAIVGILRREGLANVRKDEKGLVLEITEKGEKLGERPIDIALKLLSEKGEVSVDEISRIIDVKDLKRRKIAREDERVERTVEITEKGKKLVSKGIELKREVTRLTPELIASGKWREVELKPFNIKAPVKRIYPGKKQPYRVFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPEKGYLPDESLVSRVKEAHERGLAGSRGWGYVWSPERAMLLMPRAHATALSARQLAKGIEIPGKYFTIQRVFRPDVLDRTHLIEFNQIDGFVAGEDLTFRHLLGILKRFAIEIAGAKKVKFFPDYYPFTEPSVQLSAYHPELGWVEFGGAGVFREEMTEALGIKVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLRWLREAKLIW
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_RABIT
Sequence: MFVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKAPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFAHWFPLFSGYTLDPTWAKIHFTVMFVGVNLTFFPQHFLGLSGMPRRYSDYPDAYTMWNTVSSMGSFISLTAVMVMIFMIWEAFASKREVETIELTTTNLEWLHGCPPPYHTFEEPAFVKA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRUB_THET8
Sequence: MALYAVDKPLHLTSHDVVEEARRRLSTRRVGHTGTLDPLATGLLLLVTNESTKLVPFLSGEDKEYIAWVSFGATTPTLDAEGPISEEAPARFDRKDLEAALPRFLEVREQVPPLYSAIKVGGKRAYEAAREGKPLALGPRPVRYLEVELLAFDPEPIPHPIAPSARGWRLAERRGRPVRLPRPLGAYPTAVVRLVVGPGTYVRAFARDLGEMLGTKAFLSGLVRTRVGRVGLERAVALSDLSPEKAIPELDVLPFPVVELSHTEARRVLEGMPLPIPAMGYVTLVDSKRRLLAIAEGDGFKLKIRRVFAKEA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y219_HAEIN
Sequence: MEIYMSVFNTFVEFVARIVAPMQRQFINFIRIAIFIVMAWIGGLKVCQYEADGIAHFVSNSPFFSYMYEKGPNLVPNDKGELVMEYTLHKNPEGKMVAKNIEWHKENGTYTASYIIGAIIVTVGILTLAGIWNATAGLAGGLLTFGMSIVTLSFLITTPEAWVPNLGGDLPTPAYGFPYLSGVGRLVIKDIIMMAGGLTAAAECANRILARKK
What are the official names of this protein?
Uncharacterized protein HI_0219.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSA_MYCVP
Sequence: MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSLQKVSELYDRIGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHHGETKAPELYRITYDGSIADEPHFVVMGGTTEPISTALNESYKENLSLADAVSIAVKALGAGVNGAEPRTLGPATLEVAVLDANRPRRAFRRITGSALEALLPEVDSSESSNEAEAGAEKGSGES
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_STRZT
Sequence: MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: HIS1_YERPA
Sequence: MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_CALS4
Sequence: MKIAVLGAGSWGTAIAIHLNKLNHQVRLWMRSKEQFEELIATRHNSRYLDVDLPSSILLYNDLDKAVEDSEVVVIAVPSHAVREVSEKLKGKISKNAIVVNLAKGIETSSLKRMSEVIKEYLLNPVVVLSGPSHAEEVVRQIPTACVLASEDVKACEFIQEAFMNETFRLYVNTDVIGVELGGALKNIIALGAGISDGLGFGDNTKAALMTRGLAEITRLGVAMGSDPLTFLGLAGVGDLIVTCTSNYSRNRRAGILIGKGKSLKEALKEIGMVVEGVNTTKSAYRLSQIYGVEMPITKEIYSIIFENKNPFEAVYNLMTRDKKHELHGI
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_ALKOO
Sequence: MNIHEYQAKELLRDYGVPVPRGQVIYDVRDAQRAAWHIESDIAVVKAQIHAGGRGKAGGVKIAKSITEVEQFSRELLGKTLVTHQTGQEGRVVKAILIEEGCEIYKEYYIAFTLDRENSKIALIASEEGGMDIEEVAANRPDKILKEIIDPLIGLTDFQGRRVCFNLNIDGSLINDTVELMKNLYRCFIEKDCSLLEINPLVITKNNRVMALDAKINFDGNGLYRNEDVLKLRDLNEEDEKEIEASKYNLSYISLDGNIGCMVNGAGLAMATMDIIKLYGGNPANFLDVGGGASEEKVMNAFKIILSDPKVKGIFVNIFGGIMKCDVIAKGIVNAANEVKLNVPLVVRLEGTNVELGKEILNQSNLNIVTATTMADGAKKIVKLIK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SSUD_YERPB
Sequence: MSINVFWFLPTHGDGHYLGSSEGARAVDYSYLQQIAQAADRLGFGGVLIPTGRSCEDSWLVAASLIPVTQRLKFLVALRPGIISPTLAARQAATLDRLSNGRALFNLVTGGDPEELAAEGLHLNHTERYEASAEFTHVWRKVLEGETVDFAGKHIQVKGAKLLFPPVQHPRPPLYFGGSSAAAQDLAAEQVELYLTWGETPEQVKEKIEEVRAKAAAKGRTVRFGIRLHVIVRETTEEAWRAANRLIANLDDKTIADAQQAFARFDSVGQQRMAALHGGKKDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAQRIQEYADLGIDTFVFSGYPHLEEAYRVSELLFPHLDLATTELPTQRPATQPQGEVVANIYVPQKVSQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: THII_MYCAP
Sequence: MYEKILIRYGELTLKGKNRDSFIAQLARNIKLITGEYPETKYDRMFLTYSDANLEKLQYVFGITSYSPVIFCENNLEKITNSAIKLVNKDDKTFKISARRNNKKFELTSAEINQKVGASVLKHYPLIKVDVHNPECNINIEVRSDKTYLFSKTYEALGGLPVGISGSTLHLMSGGIDSPVAAFKLMKRGLKVSFLSFISPPQTDEKTIGKIKDLVSVLSKYQGKSHLYLANYSKLMNYISFTSNESYRINLMRRSFYRIASKFAKGKNIMTLSNGENLGQVASQTIESLSTIASASDLLILRPLIANDKVETINIAKQIKTYDISIEKAKETCELFAPKNPVTKPNLATALRLEEELTQLKDLEEELLANEIEHYTIE
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.