PharMolix/UniProtQA huggingface dataset:
Protein: IDI2_STAAN
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMAYPIYINAMTGGSEWTKNINEKLAVVARETRLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEIMSWIEQRSLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SALPA
Sequence: MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHT_BOTF4
Sequence: MPAQIKKYKAAAVQAEPGWFDLELSVKKTIHWINEAGKAGCKLVAFPEVWIPGYPYWAWKVNYQQSLPMLKAYRENSLASDSDEMRRIREAARENAIYVSLGYSEIDFATLYISQVLISPTGEVLNHRRKIKPTHVEKLVYGDGAGDTFKSVVQTDIGRVGQLNCWENMNPFLKAMNVSEGEQVHIAGWPIYPHEETRTPLDPWTNTSNPNSDIVSPAYAIETATYVLAPFQRISKEGVDKCTPPGVEREDHNLYNGNSRIFGPDGQCLAKADEEFEGLMFVEIDLDQSHLPKALGDFGGHYMRPDLIRLLVDTRRKELITEADQDGGIGTYNTQDRVGLNRPLDAPKVDGPSGVSKQVLLSNAKKAAHKG
What is the function of this protein?
Catalyzes the hydration of cyanide to formamide.  Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants (By similarity) (PubMed:26521240).  Can also transform some nitriles like 2-cyanopyridine and fumaronitrile and has a minor activity with 4-cyanophenyl acetonitrile (4-CPA) (PubMed:26521240).
What are the official names of this protein?
Cyanide hydratase, CHT, Cyanide-degrading nitrilase, Formamide hydrolyase, NitBf.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: HFQ_METFK
Sequence: MSVKGQMLQDPFLNTLRKEHVPVSIYLVNGIKLQGQVDSFDQYVILLKNTVTQMVYKHAISTIVPGRAVSIPHGPTPTSES
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CLPP_STRU0
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGTGSGTQQTDMAIVAEQLLKTRKRLEKILSDNSGKTIKQIHKDAERDYWMDAKETLEYGFIDAIMENNELK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ3_ARATH
Sequence: MLASVRVNQLQRLLLSARRLSSSPIIPPSRLLHQRLFSTSDTDASAASFSSSHPKIQTLEGKASNKSRSTSSTTSLNEDELAKFSAIADTWWHSEGPFKPLHQMNPTRLAFIRSTLCRHFSKDPSSAKPFEGLKFIDIGCGGGLLSEPLARMGATVTGVDAVDKNVKIARLHADMDPVTSTIEYLCTTAEKLADEGRKFDAVLSLEVIEHVANPAEFCKSLSALTIPNGATVLSTINRTMRAYASTIVGAEYILRWLPKGTHQWSSFVTPEEMSMILQRASVDVKEIAGFVYNPITGRWLLSDDISVNYIAYGTKRKDLGDI
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, mitochondrial, 3-demethylubiquinol 3-O-methyltransferase, EMBRYO DEFECTIVE 3002, Polyprenyldihydroxybenzoate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: HEM1_THEYD
Sequence: MSLIVIGLNHKTAPVEIREKIAFNSKEAIKEALKELIQREGIGEVVIISTCNRVEIYVYTANVSDLKRENQVEETIKAFLSNFHNIEIGEFENYLYVYKDTEAVEHLFKVASSLDSMIVGEPQITGQVKESYEIALSERTTSLILNYLMNRALFTAKRVRNETRIGENPVSVSYAAVGLIKKVFDELSKKSILLVGAGEMAELALRHLIGSGIKNVYLTNRTFQRAEEIAKEFNGVAVPFGNLKEQLVKTDIVICSTGAPHYVITEQMLKEVMPLRKHKPIFFIDISVPRNVDPACNELDNVYLYNIDDLQDVVDSNILERKKEAEKALSIVQEETEKFFQWLNSLESVPVIVSIRNKAEQVRQEEIEKFKAKYKDLPPELINSIDYLTQSIINKIMHSPTVALKNNCENKEILIFSARRLFGLDSEEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TAL_CAMJ8
Sequence: MKNFSLWCDFIENSFLDNEFLNLLSHGINGATSNPAIFKNAILNSPIYKDKILKLKGKRTKDIYEELAISDIQKAADKLAPLFYQKNDGFISIEIDPRLHDNTTLSLGEAKRLYSAISKENVMIKIPATKASYEVMYELMKNGISVNATLIFSLEQSQKCFEALNAGLVEFRKNNIALKEQNTRTPQAVISIFVSRFDRLLNPKAKEQNRIGILNANLAYNNIYSKNEPNIRALFASTGVKGDDLPKDYYIKELLFENSVNTAPLDAIEAFKGKMDFKKPLMNFEIYTELNQIISQSEREKACNDLLSDGIEQFCIAFEDILKAL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_STAES
Sequence: MSNKAWGGRFETQPEEWVDDFNASIDFDKNLIKQDVQGSIAHATMLAKQHIITDDEAQSIINELKNIQSDFEEGKLKFKASLEDIHLNIEHELIQRIGEAGGKLHTGRSRNDQVATDMHLYTKEQVQYIIELIASFQETIVQLADQHVDTIMPGYTHLQRAQPISFAHHIMTYFWMLERDKGRFMDSLKRIDISPLGAAALSGTTHPIDRHLTQELLGFANLYENSLDAVSDRDYIVETLHHISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLVTLKGLPLAYNKDMQEDKEGLFDAVHTLKGSLRIFEGMVASMKVNSNRLSQTVKNDFSNATELADYLVSKSVPFRTAHEIVGKIVLNCIHKGIYLLDVPLSEYQEHHENIEEDIYDYLTPENCLKRRQSYGSTGQESVKHQLKVAKALLKDNESK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_MARSD
Sequence: MPQNQSDIRRVFLHTGDAYLGVKPTIVSTVLGSCVAISMFSPRKRQGIICHAFLPSRAEIKDVNEPSIQICRYVDTAVDHLLKSMRRLGVRKNELEVKLFGGATGLSYSQVRPSCALGIGNRNVDAALENLEAKGLKPVSMDVGGNVGRKLLFCTYSGDVWIKRLEKHMF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: DDL_BURTA
Sequence: MSGIDPKRFGKVAVLLGGESAERDVSLNSGRLVLQGLRDAGIDAHPFDPAQRPLAALKDEGFVRAFNALHGGYGENGQIQGALDFYGIRYTGSGVLGSALGLDKFRTKLVWQQTGIPTPPFETVMRGDDYAARAKDIVAKLGMPLFVKPASEGSSVAVEKVKSADALPAALEEAAKHDKIVIVEKSIEGGGEYTACIAADLDLPLIKIVPAGEFYDYHAKYIANDTQYLIPCGLDAAKEAEFKRIARRAFDVLGCTDWGRADFMLDAAGNPYFLEVNTAPGMTDHSLPPKAARAVGISYSELVVKVLSLTLD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT9_ACTER
Sequence: MASSVRLVKKPVLVAPVDPTPSTVLSLSSLDSQLFLRFPIEYLLVYASPHGVDRAVTAARVKAALARSLVPYYPLAGRVKTRPDSTGLDVVCQAQGAGLLEAVSDYTASDFQRAPRSVTEWRKLLLVEVFKVVPPLVVQLTWLSDGCVALGVGFSHCVIDGIGSSEFLNLFAELATGRARLSEFQPKPVWDRHLLNSAGRTNLGTHPEFGRVPDLSGFVTRFTQERLSPTSITFDKTWLKELKNIAMSTSQPGEFPYTSFEVLSGHIWRSWARSLNLPAKQVLKLLFSINIRNRVKPSLPAGYYGNAFVLGCAQTSVKDLTEKGLGYCADLVRGAKERVGDEYAREVVESVSWPRRASPDSVGVLIISQWSRLGLDRVDFGLGRPVQVGPICCDRYCLFLPVRESTESVKVMVAVPTSAVDRYEYFIRSPYS
What is the function of this protein?
Involved in the biosynthesis of volatile esters which confer kiwifruit flavor (PubMed:21450321).  Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters (PubMed:21450321).  Exhibits acetyl-CoA:alcohol O-acyltransferase activity (PubMed:21450321).
What are the official names of this protein?
Alcohol acyltransferase 9, AeAT9.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: FKBP2_HUMAN
Sequence: MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP2, PPIase FKBP2, 13 kDa FK506-binding protein, 13 kDa FKBP, FKBP-13, FK506-binding protein 2, FKBP-2, Immunophilin FKBP13, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: Y1264_LISMH
Sequence: MWIYILVGIICLLAGLAGGFFIARRYMMSYLKNNPPINEQMLQMMMAQMGQKPSQKKINQMMSAMNKQQEKEKPKKAKK
What are the official names of this protein?
UPF0154 protein LMHCC_1264.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COX1_ORTUN
Sequence: MFINRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATMNGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDTWAKIHFTIMFVGVNLTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMVFMIWEAFASKRTVKSIPLTSTNLEWIHGCPPPFHTFEEPAFIKSPH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YQIM_ECOLI
Sequence: MLMYQTRRTYQNSNNIAVVHLLKPAWR
What are the official names of this protein?
Protein YqiM.
Protein: PHEB_CHRSP
Sequence: MLDAFSRVVTGADSKAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPSLISPSGECYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLSGLKETYASLGVPAAGNARAVGIMKATVVAFINNTSNQKKLLTPSGDCSALASEAAGYFDKVTSALA
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycocyanin-645 beta chain, PC-645.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: CIO1A_SALSA
Sequence: MKDTLALLQKFNAHPDSRCWYVAWNPKGTLLASCGGDRAIRIWGREGDSWECKTVLQDGHQRAVRKVAWSPCGNYLASASFDATTCIWKKKNDDFECLTVLEGHENEVKCVAWAPSGNQLATCSRDKSVWIWEVDEEDEYECVSVVNSHTQDVKHVVWHPTQELLASCSYDNNVCVYKEEDDDWECRATLEGHTSTVWGLTFDPSGQRLASCSDDRTVKIWKECQPGGGQDTAWKCVCTLSGFHGRTVYDIAWCPLTGALATACGDDGVRVFKEDETADPDQPVFSLSAHVPKAHSQDVNCIAWHPKEAGLLVSCSDNGEIAVWNYQSEV
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein ciao1-A, WD repeat-containing protein 39-A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: RS19_SHESA
Sequence: MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NHL1_ARATH
Sequence: MKDCENHGHSRRKLIRRIFWSIIFVLFIIFLTILLIWAILQPSKPRFILQDATVYAFNVSGNPPNLLTSNFQITLSSRNPNNKIGIYYDRLDVYATYRSQQITFPTSIPPTYQGHKDVDIWSPFVYGTSVPIAPFNGVSLDTDKDNGVVLLIIRADGRVRWKVGTFITGKYHLHVKCPAYINFGNKANGVIVGDNAVKYTFTTSCSVSV
What is the function of this protein?
May play a role in plant immunity.
What are the official names of this protein?
NDR1/HIN1-like protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PTP5_CAEEL
Sequence: MVRVCRVVPKDWSKFQPVGNVIPRTRFIVFKTPINSQLSTKIHKEQRFTTNDLFRQLSERGQYLGLVVDLSDTDRYYDKKDITGMCVQYEKVNCPGRGFIERDDCVESFHQVIQDYTDKCDDPDALIGVHCTNGINRCGYLICRFLIDRLGWSSHEAIDAFEQARGYSIEKGAYVMALHKAAKDKRDKQVDSDSDSSERQRKKKNKRKHREIVEHENIVLINTIIGELGSQAASVSGTDYQNSPNGVSVDPGQPQPHHWGFAIKRSKYAQLNQPVANGANTPPEPSEGTPQEEEEFEEDFEEIEEETETEPGKGQSVSSKRRARRNRMQKYMQVMQRGRFHEIQAIREEVALSHGSARD
What are the official names of this protein?
Probable tyrosine-protein phosphatase F54C8.4.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
Protein: PYRG_ECODH
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GLYA_PYRAR
Sequence: MLPKELEEIIDVVLVHNNWRRRETINLIASENVMSPLAELVYLNDMAGRYAEGTVGNRYYQGTKYVDLIEDVLTKRFAKALGATYVDVRPVSGTVANLATYFALVPEGGVVASLPVKYGGHISHNTVGGLKALRLKMVELPWDLDRFNIDVDRARKVIEEAKPNLVILGGSLYLFPHPIREIAEIAKASGAYVLHDSAHVFGLIIGGVFPNPLKEGAHVITTSTHKTFPGPQGGLIAAVVEDKVNDLQRAVFPVFTSNYHLHRYAATYVTLVEMEHFGAEYARRVVENARALAEALAEQGVPPVAEALGYTRTHQVAVDVSKFGGGDKVAAKLEEANIIVNKNALPWDKSVLKPSGIRLGVQEMTRFGMGKDEMREIAKFIARVLSGEDPAGVRRDVAEFRKAYLEIKYGFKIDRELVDKVFKSLSLYT
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR3_AUSRA
Sequence: GPDSSFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-3, FMRFa-3.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_BORBU
Sequence: MIDKKQKQKIVSEFGKNESDTGSVGVQIALITGRIKYLTEHLKINKKDHSSKRGLLKLVGQRRSLLRYYQKKDLEAYRMLISKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GLGA_METSB
Sequence: MSEISVLAIVSEIFPLIKTGGLADVAGALPAALAGEGIEVATLVPGYPAVMAQIEYAETVIDARPLYGAPARVLRGSAAGLDLFVLDAPHLYDRPGNPYLLPDGRDFPDNPFRFAALCQTGSALGFGAAPGFLPDIVHAHDWQAGLAAAYLHYDGRERPGTVATIHNLAFQGKYPAELLGALGLPPQAFSLEGVEYYGTIGFLKAALALSDRITTVSPTYAAEIRTPEHGMGLDGLLRTRAERLIGILNGIDDEVWDPSSDPLITEPFDVETLARRPANKAALQDKFGLDPDPGALLLGVVSRLSWQKGLDLLLANLDLLERLGVQLAVLGSGEPELVRQLLEAAEARPGRVGAVIGYDEAIAHRIQAGADAIVIPSRFEPCGLTQLCALRYGALPIVARVGGLADTIIDANEMALASGIGTGLQFSPPTADMLGATLERAARLWAEPEIWDELIENGMLTDVSWRRPAALYAKLFRDLVRER
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: YM09_YEAST
Sequence: MLRQFGGVFRNLRVPERTNALLFAQHKGDERHSGQRAFDGSKFRLEAKRCFTAICIITVARRDRLGVLVCGKNTASTLPYLPANRIFRLPKVQIRKMFPIGCATFLSREYIITALLVSYCHLCV
What are the official names of this protein?
Uncharacterized protein YMR122C.
Protein: HISX_SYNY3
Sequence: MTRILKLSHLTPQQLNQLKRRSEQNIDQALAIAKEVIEQVKMEGDAGVLHYSRQFDFAGATAENLRVSEAEFAEAEKLVDPELRRAVEHAFRNIEKVHAGQMPPPMHLAEIEPGVFAGEKITPLPTVGLYVPRGKGAFPSMMLMLAVPARVAGVKKIVVCTPPDKEGKVEPVSLVTARMAGVDEVYKLGGVQALAAIAYGTKTVSKVDKLIGPCSIYGAAAKRLLSGIVDVGLPAGPSESIVLADETTDPKLAALDLLIEAEHGSDSAALLVTHSASLAEKALGYLGEYLEKLPPWRKKFCEDGLGSYGGILLTDSLQASLDFINDYAPEHLQVLTADPLKLVGKIDNAGEILLGNYTPSSAATYAIGVNAVLPTGGFARSYSAVSVFDFLKRSTLAYLTEEGFAGVKETVTTLADYEDFPAHALAIRERENLL
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: INAR1_BOVIN
Sequence: MLALLGATTLMLVAGRWVLPAASGEANLKPENVEIHIIDDNFFLKWNSSSESVKNVTFSADYQILGTDNWKKLSGCQHITSTKCNFSSVELENVFEKIELRIRAEEGNNTSTWYEVEPFVPFLEAQIGPPDVHLEAEDKAIILSISPPGTKDSIMWAMDRSSFRYSVVIWKNSSSLEERTETVYPEDKIYKLSPEITYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENIQINADNQIYVLKWDYPYENATFQAQWLRAFFKKIPGNHSDKWKQIPNCENVTSTHCVFPREVSSRGIYYVRVRASNGNGTSFWSEEKEFNTEMKTIIFPPVISVKSVTDDSLHVSVGASEESENMSVNQLYPLIYEVIFWENTSNAERKVLEKRTNFIFPDLKPLTVYCVKARALIENDRRNKGSSFSDTVCEKTKPGNTSKTWLIVGTCTALFSIPVVIYVVSVFLRCVKYVFFPSSKPPSSVDEYFSDQPLRNLLLSTSEEQTERCFIIENASIITEIEETDEIDEVHKKYSSQTSQDSGNYSNEDENSGSKISEEFPQQDSV
What is the function of this protein?
Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) (PubMed:8318540).  Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response (By similarity).  Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another (By similarity).  The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors (By similarity).  STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes (By similarity).  Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
What are the official names of this protein?
Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Type I interferon receptor 1.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome. Note=Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes.
Protein: TUSC_PECAS
Sequence: MKRVAFVFTHSPHGSTSGREGLDALLAMSALTEEIGVFFVGDGVLQLLPHQQPEKILMRNYIATFGVLPLYDIECCYLCEASVRQRGLSIDTNWVLDVELLAPKAWRSKLADYHSILSF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.