PharMolix/UniProtQA huggingface dataset:
Protein: RM20_YEAST
Sequence: MIGRGVCCRSFHTAGSAWKQFGFPKTQVTTIYNKTKSASNYKGYLKHRDAPGMYYQPSESIATGSVNSETIPRSFMAASDPRRGLDMPVQSTKAKQCPNVLVGKSTVNGKTYHLGPQEIDEIRKLRLDNPQKYTRKFLAAKYGISPLFVSMVSKPSEQHVQIMESRLQEIQSRWKEKRRIAREDRKRRKLLWYQA
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L20, mitochondrial, Mitochondrial large ribosomal subunit protein mL58, YmL20.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL58 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: PUR72_CAUVC
Sequence: MTLSAPNALAVVDLPCLPNHYRGKVRDNYDLPDGRRVIVASDRLSAFDRNLCAVPGKGQVLTETARFWFDATADICPNHVVAYPDPNVLIGKRLKMLPVELVVRGYLAGTTSTSILTLYNKGERQMYGVTLPDGLKANQRLPQAILTPTSKAADGDHDAPLSPDEVLAQGLVTPAQWEQLSAYALALFARGQAMAAERGLILADTKYEFGLDETGAIVLADEIHTPDSSRFWKAATYEARFEAGQRPESFDKDFVRAWVAERCDPYNDSIPEIPAELIAQASAVYIEAFEAITGQTFAAPDASEPVMARVKRNLDAYLAG
What are the official names of this protein?
Putative phosphoribosylaminoimidazole-succinocarboxamide synthase 2, SAICAR synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DAPAT_LACP7
Sequence: MFKINENYLKLQGSYLFSTIGKKVRTYKEENPDKNVISLGIGDVTLPLAPSIISALHKATDEMAAKETFKGYSPDLGYEFLRSAIAKHDYEARGVQIALDEIFISDGAKSDSGNIGDIFAENNKIAVCDPVYPVYVDTNVMAGRTGEFNYTTGKWSNVIYMPCTKENKFVPSLPAETPDIIYLCFPNNPTGSAITKMKLQKWVDYAIEKGAVIIYDAAYEAYISEENCPHTIYECDGAKKCAIELRSFSKNAGFTGTRLGFTIVPKELTSDGVSLNSLWARRHGTKFNGAPYIIQTAGAAVYSPEGIAETREQINYYMNNARVIRDGLLEAGYQVSGGVNAPYIWLHTPDGMTSWEYFDYLLQNASVVGTPGSGFGPSGEGYFRLTAFGTYENTLEALRRIKNL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: RL33_BORDL
Sequence: MGKKKGKGAVGLIALVCEETGIRNYTTTKNRRNTQEKLELMKYCPSLRKHTLHKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: GALDH_ARATH
Sequence: MTKIELRALGNTGLKVSAVGFGASPLGSVFGPVAEDDAVATVREAFRLGINFFDTSPYYGGTLSEKMLGKGLKALQVPRSDYIVATKCGRYKEGFDFSAERVRKSIDESLERLQLDYVDILHCHDIEFGSLDQIVSETIPALQKLKQEGKTRFIGITGLPLDIFTYVLDRVPPGTVDVILSYCHYGVNDSTLLDLLPYLKSKGVGVISASPLAMGLLTEQGPPEWHPASPELKSASKAAVAHCKSKGKKITKLALQYSLANKEISSVLVGMSSVSQVEENVAAVTELESLGMDQETLSEVEAILEPVKNLTWPSGIHQN
What is the function of this protein?
Catalyzes the oxidation of L-galactose to L-galactono-1,4-lactone in the presence of NAD(+).  Uses NAD(+) as a hydrogen acceptor much more efficiently than NADP(+).
What are the official names of this protein?
L-galactose dehydrogenase, At-GalDH, L-GalDH.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: METH_ALIF1
Sequence: MAGSNIKVQIEKQLSERILLIDGGMGTMIQGYKFEEEDYRGERFNKWHCDLKGNNDLLVLSQPQIIRDIHEAYLEAGADILETNTFNATTIAMADYDMESLSEEINFEAAKLAREVADKWTEKTPNKPRYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYSESTRALIRGGSDLILIETIFDTLNAKACSFAVESVFEELDITLPVMISGTITDASGRTLSGQTTEAFYNALRHVKPISFGLNCALGPDELREYVSDLSRISECYVSAHPNAGLPNAFGEYDLSPEDMAEHVAEWASSGFLNLIGGCCGTTPEHIRQMALVVEGVKPRQLPELPVACRLSGLEPLTIEKDSLFINVGERTNVTGSARFKRLIKEELYDEALSVAQEQVENGAQIIDINMDEGMLDAEACMVRFLNLCASEPEISKVPVMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGKEKFVHQAKLIRRYGAAVIVMAFDEVGQADTRERKIEICTNAYNILVDEVGFPPEDIIFDPNIFAVATGIDEHNNYAVDFIEAVGDIKRTLPHAMISGGVSNVSFSFRGNNYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEDLREAVEDVVLNRRDDSTERLLDIATEYLERAVGKVEDKSALEWRDWPVEKRLEHSLVKGITEFIVEDTEEARINAEKPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPFINASKEVGATNGKILLATVKGDVHDIGKNIVGVVLQCNNYEIIDLGVMVSCETILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFDLPLLIGGATTSKAHTAVKIEQNYSQPVVYVNNASRAVGVCTSLLSDELKPSFVEKLDIDYERVREQHSRKQPRTKPVTLEVARANKVAIDWASYTPPVPLKPGVHIFDNFDVSTLRNYIDWTPFFMTWSLVGKYPKILDHEEVGEEAKRLFKDANDLLDRVEKEGLLKARGMCALFPASSVGDDIEVYTDESRTKVAKVLHNLRQQTEKPKGFNYCLSDYIAPKESGKNDWIGGFAVTGGIGERELADEYKANGDDYNAIMIQAVADRLAEAFAEYLHEKVRKEIWGYSPNETLSNDDLIREKYQGIRPAPGYPACPEHTEKGALWELMNVEESIGMSLTSSYAMWPGASVSGMYFSHPDSRYFAIAQIQQDQAESYADRKGWNMLEAEKWLGPNLN
What is the function of this protein?
Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine.  Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).
What are the official names of this protein?
Methionine synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase, Methionine synthase, vitamin-B12 dependent, MS.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 dependent methionine synthase family.
Protein: RL4_BURCM
Sequence: MELKLLNENGQEGAVVNASDVVFGRDYNEALIHQVVVAYQANARQGNRAQKDREQVKHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPEENFSHKVNKKMHRAGLCSIFSQLAREGRLSVVEDIILEAPKTKLLADKFKTMGLDSVLIITDTVDENLYLASRNLPHVAIVEPRYADPLSLIYFKKVLVTKAAVAQIEELLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y4007_XANAC
Sequence: MNSDIISGKWTQLKGKAQAKWGDLTDDDFKVAEGNAEYLQGKLQERYGWDRDRAQTEVRAFEKSLRDDT
What are the official names of this protein?
UPF0337 protein XAC4007.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: LDH_CLOBJ
Sequence: MIKKRNTTKISVIGAGSVGATTAYALMLSGVATEIVLVDVNKSKTEGEAMDLSHGADFVKPVNILSGDYKDTEGSDIVVITAGAAQKVGETRLQLINKNINIFKSIIPEVVKYNKDAILLVVSNPVDVLSYVTYKLSGFPKERVIGSGTVLDTSRLKHEIGKRYKIDPRNVNTYIMGEHGDSEIATWSVTNIQNIKIDEYANKENLEYNDNFRKEVYENVKNAAYEVINRKGATFYAIALAVTRIVKAILGDEKTILPVSTLVENYYGIKDVYLGMPCIVGGSGIEKALSIDLNKTEASKLVKSAETLKNTLNNASCL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_KLEP7
Sequence: MHEITLSQRALEIIEQQAQQAGARRVTGVWLKVGAFSCVEASALTFCFELVCRGTLAEGCELHIAEQQAECWCDRCQQYVHLVSQHVRRCPHCNNDQLQIVADDGLQIQRLELE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: UBIC_SHIFL
Sequence: MSHPALTQLRALRYFKEIPALDPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1A04_PANTR
Sequence: MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDEETRSVKASAQTDRVDLGTLRGYYNQSEDGSHTIQLMFGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWEAAHAAEQLRAYLEGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDREATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDVSLTACKV
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Patr class I histocompatibility antigen, A-126 alpha chain, ChLa class I histocompatibility antigen, A-126 alpha chain, MHC class I antigen Patr-A*0401.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CY069_POSPM
Sequence: MVISTNELAALTVVLLATGVLFYANSTRRAPLPPGPRGLPLLGNLFQFDVMRPYPQYLKWAQKYGPVFSVKLGGQRIIVLNSSEAADELLATRSKLYSSRESPHVGFDLVSDQQRMLFMPYGREWKIARKNVHSLLGPGPSKQMGKTQDLESRVMLHDLLCHGETSITEEFVEGPRGEVPERHWFSIVRRYTTSVVMMLVYGRRIHRIVGNPELHKVYDLMSNFTHVSQPGRYMVDALPVLRWLPDMLAPWRAEGRKMHKREMDFWGKLFSDSRTAFLNGTGLNGFVQSYLRARTEAGLEDLPGNGATEDAAGWMRDKLITYTAVTIVEAGSDTTSTGVFSFVLLMLSNPDALQRAKEEMDAVVGSSRMPDWEDEDRLPWLTACIKETLRRAPPAPLGIPHKVDEDDVYNGYLIPKGSTVIGNIWAIHMDPVRYPDPTAFKPERFYNPDGKLNWASGPDAHNRDHYIFGWGRRFCSGKYLAEASMFIVLSRLIWGFDFYAASDPQTGKARLPDVSDVDTFTDGLVTAPKIYPVGFKPRSEKHAEMIKASYRDVQNDWQSMGLAGDER
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use 4-ethoxybenzoic acid as a substrate for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 69.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RF2_PSET1
Sequence: MFEVNPVINQIKEIRERTELLRGYLDYALKQERLEEVNAELEDSAVWNEPERAQALGREKSALEAVVETIDTLVTGTDDVEGLLELAVEAEDQETFDEAQSELADLNEQLEALEFRRMFSGPHDSNDAYLDLQSGSGGTEAQDWCNILLRMYLRWGEAKGFKVELVEATGGDVAGIKGATVRFVGEYAYGWLRTETGVHRLVRKSPFDSSGRRHTSFASAFVYPEVDDNIEIDMNPSDLRIDVYRASGAGGQHVNTTESAVRITHVPTNTVVQCQNERSQHKNKAQAMKQLKAKLFELELQQQNAEKQTQEDSKSDIGWGSQIRSYVLDDARIKDLRTGVESRNTQSVLDGNLDKFIEASLKSGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_MYCPA
Sequence: MPKLLPPVVLAGCVVALGACSSPQHASSLPGTTPAVWTGSPSPSGAGAAEAAPAAAPSITTHLKAPDGTQVATAKFEFSNGYATVTIETTANGVLTPGFHGVHIHKVGKCEPSSVAPTGGAPGDFLSAGGHFQAPGHTGEPASGDLTSLQVRKDGSGTLVTTTDAFTMEDLLGGRKTAIIIHAGADNFANIPAERYNQTNGTPGPDEMTMSTGDAGKRVACGVIGAG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.  May play a role in favoring mycobacterial survival in phagocytes (By similarity).
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DNAJ_BACC0
Sequence: MSKRDYYEVLGLSKGASKDEIKKAYRRLAKKYHPDVSKEENAIEKFKEVQEAYEVLSDDQKRAQYDQFGHAGANQGFGGFGGGGDFGGGFGFEDIFSSFFGGGGGRRRDPNAPRQGADLQYQVTLEFEEAIFGKELNVEIPVEDPCDTCKGSGAKPGTSKETCKHCSGSGQVSVEQNTPFGRIVNRQACSHCSGTGQMIKEKCTTCHGSGKVRKRKKINVKIPAGIDNGQQIRVSGKGEAGVNGGPXGDLYVVVHVRSHEFFEREGDHIICEMPLTFAQMALGAEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTKLTSHQKDLLREFAGQEEQDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GON2B_CARAU
Sequence: MVHICRLFVVMGMLMFLSVQFASSQHWSHGWYPGGKREIDVYDPSEVSEEIKLCNAGKCSFLIPQGRNILKTILLDALTRDFQKRK
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin IIB.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARSC_GEOTN
Sequence: MKNKKIIYFLCTGNSCRSQMAEGWAKKYLGDDWEVYSAGIEAHGLNPNAVKVMKEVGIDISNQTSDVIDPEILNKADLVVTLCGHAADHCPVTPPNVKRVHWGFDDPAKAEGTEEEKLAVFRRVRDEIGARIKKFAETGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_MESH7
Sequence: MAKTSWKVKANRAPKFKVRAYTRCQLCGRSHSVLRKFRICRICFRVLAHQGRIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: ALF1_CLOAB
Sequence: MNETQMNRISKDKGFIAALDQSGGSTPKALLQYGIKENSYSNDEEMFNLVHEMRKRIIKSTAFNSKYILGAILFENTMYRTIDHKYTADYLWNEKNIVPFLKIDKGLSELENGVQLMKPITNLDELLKAAIEKNIFGTKMRSFIKEANSKGIKMVVDQQFELADKIANQGLVPIIEPEVDIKSTDKEKSEELLKLEISKHLSDLDKETKVMLKLSIPTKDNFYSDLMKDPHVVRIVALSGGYSQSEANERLSRNNGLIASFSRALSENLSIDQTDEEFNETLSNSIKEIYEASIT
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: RL17_STRPB
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS10_CERS1
Sequence: MQGQTIRIRLKAFDYRVLDASTQEIVNTAKRTGAQVRGPIPLPNKIEKFTVLRGPHIDKKSRDQWEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDIQIKV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SYL_HELPY
Sequence: MDFINIEKKWQEFWWKNKSFEPKDDFNLPKKYILSMLPYPSGEIHMGHVRNYTIGDALARYYRLHHYNVLHPMGFDSFGMPAENAAIKHGIHPKTWTYENIENMQKEFEALGFSFSKNREFATSDPDYTKFEQRFFIDLWEKGLIYRKKAMLNWCPNDKTVLANEQVIDGRCWRCDTEVIQKELYQYYLKITNYAEELLKDLEALEDHWPSQVLIMQKNWIGKSSGLQFGFKIADECLKACNGIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKQVSQEVSKMIKAILNTTQRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVPACDERDFEFANLYHIPIKVITQSPQNLPHTKEEVLKNSGEWSDLSSSVAREQIIAYFEKENLGKRVINYRLQDWGVSRQRYWGAPIPMIHCNHCGIVPETQLPVTLPEDIVIDGEGNPLEKHASWKFTQCPKCHKNALRETDTMDTFIQSSWYFLRYTTPKNQRENQAFDQNYLKYFMPVDTYIGGIEHAILHLLYARFFTKALRDLGYLHLDEPFKQLITQGMVLKNGAKMSKSKGNVVSPKEILKKYGADAARLFILFAAPPAKELEWNDSALEGAHRFIKRLYDKANAINPTTSKPEFKEVSLNEAQKLGRKKVYEALKKSHEIFNKAESAYSFNTLIASCMEALNALSAQNNERILCEGYFVLLQILEPIIPHTAWELSERLFKRENFKPIAIDEDALMEDFMTLGLTINGKRRAELKVNINASKEEIIVLAKKELEKYLENASVKKEIYVPNKLVNFVIA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHCA_LIMFS
Sequence: MKTPLTEAVSIADSQGRFLSSTQIQVLFGRFRQAKAGLXAAKAL
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: HIS4_METMJ
Sequence: MEIYPAVDILDGRCVQLVQGRPEAATVYGDPAAWAHRWLDEGADGLHVVNLDGAFGRARKNADLIRAFTRETETFTELGGGIRSVEDAAGWLDAGVDRVIVSTQAVREPEMIRTLAEEFGGERVMAGIDARAGEVMIEGWERPAGSYLSWAERFESLGAGSLLYTNVDVEGLQQGIAIEPVTELLARVKVPVVVSGGISSPGDVAALRDAGAAGAVLGSALYAGKVRLPEAMEAAHANE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_HERA2
Sequence: MRTFFRPALAAIIIFSVLTGVIYPALVTVIAQVTFPGQANGSLIEQAGQQRGSSLIGQQFDQPEYFWGRLSATGPVPYNAAASSGSNYGPLNPALAEAVQARIDALKAADPSNQLPIPVDLVTASASGLDPEISPAAANYQVQRVAAARGLAVEQVQQLVEQHTSQRTLGVLGEPRVNVLQLNIALDQIKSLD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GUAC_STACT
Sequence: MKIFDYEDVQLIPNKCIVKSRSECDTSVQFGPKRFKLPVVPANMQTVMNEKLAEWFAENDYFYIMHRFDEEGRIPFIKKMQDKGLFASISVGVKDKEYDFVRELAEEGLKPEYITIDIAHGHSEQVINMIRQIKSYLPETFVIAGNVGTPEGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAAINHCSKAARKPMIADGGIRTHGDIAKSIRFGASMVMVGSLFAAHEESPGETVELDGKLYKEYFGSASEFQKGEHKNVEGKKMFVEHKGTLADTLTEMQQDLQSSISYAGGKDLDSLRKVDYVIVRNSIFNGDRD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: ADIP_HUMAN
Sequence: MGDWMTVTDPGLSSESKTISQYTSETKMSPSSLYSQQVLCSSIPLSKNVHSFFSAFCTEDNIEQSISYLDQELTTFGFPSLYEESKGKETKRELNIVAVLNCMNELLVLQRKNLLAQENVETQNLKLGSDMDHLQSCYSKLKEQLETSRREMIGLQERDRQLQCKNRNLHQLLKNEKDEVQKLQNIIASRATQYNHDMKRKEREYNKLKERLHQLVMNKKDKKIAMDILNYVGRADGKRGSWRTGKTEARNEDEMYKILLNDYEYRQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRESMWDLSCETVREQLTNSIRKQWRILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERKAFEEERASWLKQQFLNMTTFDHQNSENVKLFSAFSGSSDWDNLIVHSRQPQKKPHSVSNGSPVCMSKLTKSLPASPSTSDFCQTRSCISEHSSINVLNITAEEIKPNQVGGECTNQKWSVASRPGSQEGCYSGCSLSYTNSHVEKDDLP
What is the function of this protein?
Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs).  May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity).  Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity).  Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles.  The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777).  Involved in ciliogenesis (PubMed:24356449).  It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).
What are the official names of this protein?
Afadin- and alpha-actinin-binding protein, ADIP, Afadin DIL domain-interacting protein, SSX2-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the ADIP family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Not found at cell-matrix AJs.
Protein: SSRP_CLOB1
Sequence: MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPLRDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.