PharMolix/UniProtQA huggingface dataset:
Protein: Y1356_PYRNV
Sequence: MGRVGVVSWGAYIPKYRIRTEEVARIWGDDPLRIVDLYLVDEKSVEGIDEDAVTIAVEAARRALRRATLDPRRIGAVYVGTESKPYAVKPISSILIDALGLSNNVFAVDMEFACKAGSEGLMAAVGLVESGKVEYGMTVGADTSQGEPGEHLEYSASSGGVALVVGREGVAAELEAAYAYASDTPDFWRREGSPYPMHGEGFTGEPAYFRHVINAARGLMAAYGYKPSDFAYAVFHQPNGRFPVRAASTLNIPMEKVKPGIVVTHIGNTYNASALMGFAKVLDQAKPGDKILVVTFGSGAGSNAYVFSATDLIKERQNAAVPTVEAMLRDKIYVDYAQYLKMRKMIKLFEY
What are the official names of this protein?
UPF0219 protein Tneu_1356.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: DPCKG_PYRFU
Sequence: MSVMFKLPLNLRQELKKPLGELIKGEIPIPYLKLKEIVNSNTLITVGDVVTENSLKVGLRPRLAIYDHKTERREYKPEIGDKGVLLTVKNPPGTITLHLLKTIKKAYSLIRRGTNVHIVVNGEEDLAAIPAVLYAPLGSFVVYGQPREGIVLIKVTSECKRRCAEIMRNMEVVRNGD
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: NDK_RHIEC
Sequence: MAIERTFSMIKPDATKRNLTGAITKMLEDAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEGMTSGPTVVQVLEGEGAILKNREIMGATNPANAAEGTIRKVHALSIGENSVHGSDAPETAAQEIKYWFSDTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_HYPNA
Sequence: MARRPEADAPPKKQAGPRINEEIRAAKVLLIDENGEKQGVMPLAAALDAAREASMDLVEVSAGQETPVVKILDYGKLRFEERKKKAAARKKQKSSELKEIKIRPNIDTHDYEVKARAIARFFEEGDKVKITLRFRGREMAHQHLGMELLEKVKKDFEETAKVELEPKLEGKQMTMVLAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDUI_LACP7
Sequence: MELRTAASPKDVKHYTTDRLREEFLIDDLFKVNEIKLVYSHIDRIITGSAVPVNQELKLTAGDELRAEYFLQRREMGIINIGGKGTITIDGTVYELEYKDGMYIGMGAKDISFASVDATNPAKFYINSAPAHTSYPTVLIKPENCVNVELGSLEGSNHRVICKYILPGQVESCQLVMGMTQLKPGSVWNTMPCHTHDRRMEVYLYFDMQENDMVFHYMGEPTETRHIIMRNEQAVISPSWSIHSGCGTKAYTFIWGMVGENQDFDDMDACDLKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RNH2_RHIE6
Sequence: MKPRTSPDSPLLFDTAPLVPDFRLELKARKAGHWPVAGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAVPASYVLTDGLDVPPGLDCPGQAVVKGDARSVSIAAASIVAKVTRDRMMARAHNVFPDYGFAAHAGYGTAQHRTGIEKHGPCSLHRMSFRPLRKSEDGPEMDELIPE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_FRAAA
Sequence: MSRIGRLPIPVPSGVDITVEGATVTVKGPKGTLSHVVVEPIAVNREEGQLVVTRPDDERRSRSLHGLTRTLVSNMVTGVTAGYSKTLEIVGVGYRVQAKGSDLEFALGYSHPVPVKAPEGIRFEVQTPTRFVVHGIDKQLVGEVSAKIRGLRKPDPYKGKGVRYQGEVVRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PYRH_SPHAL
Sequence: MALPGLKRILLKLSGEALMGPSPFGIDPETVASMAAEVKEAKDRGLEICLVIGGGNIFRGMAGAAKGMDRAQADYMGMLATVMNALAMQNALEQLGVQTRVQSAIEMDKVCEPVIRRRAERHMEKGRVVIFAAGVGAPYFTTDSGAALRAAEMKCDALLKGTSVDGVYNADPKQDANAVRYDRLSYDRVLADNLKVMDASAVALCRDNHIPIVVFNIREPGNLARVLAGEGVSTVVGDGAV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_RICMO
Sequence: YFSYNDKIIKILEAEYLNAAHHFTSGTLISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HTRA2_DROSE
Sequence: MALRGSHRLEVIFKRCIASPVLHSQAGNRRSSQLAIKGVDPNSNGNSGQYQQNGEHKEKGWRRLVRFFVPFSLGAAVSAAIIQREDLTPTIAASKMTGRRRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPEDP
What is the function of this protein?
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein.  Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism.  Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity).
What are the official names of this protein?
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment. The extramitochondrial protein does not diffuse throughout the cytosol but stays near the mitochondria.
Protein: EX7L_RHILO
Sequence: MSEAASESRTNATEYTVSEISGALKRTVEDVFGNVRVRGEISGYRGPHSSGHAYFALKDDRARLDAVVWKGTMSRLKFRPEEGMEVIATGKLTTYPGKSNYQIVIDNLEPAGAGALMALLEERKRRLQAEGLFDAGRKRRLPFMPRTIGVVTSPTGSVIRDIIHRIKDRFPLHVLVWPVRVQGDTASAEVTNAVTGFNALAWDGSIQRPDLLIVARGGGSLEDLWGFNDEALARAVAASGIPVISAVGHETDWTLIDLVADVRAPTPTGAAEIAVPVKADLEATLASLGARLKAAVLRNFERKRQAARAAARALPSPDQLLALPRRRLDEATSRLGRGLSVSVDRKRARLQGQRLTPATLSRRINEARTLTGRDLARAQAAFFAIVRERRARFARTATRLSPAPIARRQKLQADTLAALARRQDRVISLRLERLRGQLSQAERLLTTLSHKAVLARGFALVKNADGAVIKQAADVVSGMALTLEFADGTADAVATSGAARPKPAAKPSTKAKEPGNQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_NOSS1
Sequence: MASTIQALPQEVVYLITAGEVIDSFAAVVRELVENSLDAGANRIVVYLWPQQWRVRVADNGCGMNLDDLQQAASAHSTSKIRSSADLWKIHSLGFRGEALHSLTTLADVEIISRAPENVGWRVVYGDSGKAVHVEATAIAPGTVVTVSNLFASCAARRQGLPTTAQQMKAVQATIQQIALCHPQTTWQVWQNDRIWFTISPAATAGQLIPQFLPQLRPSDLQEIKLEIPNPENPQLSTNNKPNASALALVVGLPDRCHRHRPDWVRVAINGRMIKLPELEQTILAAFHRTLPRDRYPLCFVHLLISPDQINWNRNPAKTEIYLHDLSYWQEQVTQAINQALRISAANIPESVQTTRVSQLLKAAEEKGNYNFNPRNANPADNTQNYLKAVAQVSNTYIVAEHPGGMWLVEQHIAHERVLYEQLCDNWRLIPVEPPIILYQLSPAQVAQLQRIGLDIDIFGEQLWAVRNLPAMLQQREDCAEAILELSWGGDLQTAQVAVACRSAIRNGTPMSLPEMQKLLDDWQRTRNPRTCPHGRPIYLSLDESSLSRFFRRHWVIGKSHGI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: YRZ4_CAEEL
Sequence: MEVASSSSACQFDNLNNNNNELKPVRPKRDFRFKVIEVQNGPKWFVWPSRNRGSSEDVDENDNKKVSQPQNNGFGALRRSVIRQSKRKQDQDAIAARTASEPASARRLSAKKEKAVTEPLNQVSSMFKIISIEKNWESFDATDNEDNDEDLEDGARTVSVISLTSVIEGGERRWTTSI
What are the official names of this protein?
Uncharacterized protein T19H5.4.
Protein: NIFD_METBA
Sequence: MGAEIDSRIEDEQKLVDDMLKVLPEKAARNRRKHIVVRNCSTEQHIEADDKVIPGILTNRGCAFAGTKGVVFGPIKDMVHLVHGPIGCAFYTWGTRRNFAKAEEGGDNFMNYCVCTDMKETDIVFGGEKKLKKAIDEVVKIFHPEAITICATCPVGLIGDDIESVAREAEKEHGIKVIPARCEGYRGVSQSAGHHIASNALMEHLIGTEEIKSPTPFDINVFGEYNIGGDLWEVKPIFEKIGYRIVSSLTGDGSFHRISQAHQAKLSILVCHRSINYTNRMMEEKYGVPWLKVNYIGTKGTEKLLRKMAEFFDDPELTRKTEEVIAEEKAKYAEDIEKYRKKLKGKTAFIYAGGSRSHHYINLFEELGMKVIAAGYQFAHRDDYEGRQIIPQIKEKALGSILEDVHYERDENVKPTVSPERIEELKTKIGLMDYKGLFPDAEDGTIVIDDLNHHETEVLVKTLKPDIFCSGIKDKYWAQKPWSPSRQIHSYDYSGRYTGFSGVLNFARDIDMALHSPTWKFIRPPWKAENVE
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: LPXK_RUEPO
Sequence: MRAPEFWQNDPAHPGWQSRLLAPLGALYARATARRLAKGDPVSVPVPVICIGNLNAGGTGKTPSAIWVAERLRDAGHEPHVVTRGYGGTLEGPVQVDPRRHRAEQVGDEPLLLAAFAEVWVAKDRAAGTRAAAAAGASVIILDDGFQNPSVAKDLSIVVVDAAQGFGNGRCIPAGPLREPVATGLARADLVLALGDAQAQEQFRDTWGAALSVPLVTAELKPLRTGMDWAATPVLAFAGIGNPAKFFRTLRAEGADLRRAEALDDHQPLTPALMTRLENEARLLGAQLVTTEKDAVRLPPAFRSKVITLPVRLEVAEEDRLRAILLAAAPPPP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: MNME_SACD2
Sequence: MTTQTNETIAAIATAPGRGGVGIIRVSGPKALPIAQHILGITPKPRYAHYGDFCNANGDILDQGIALYFPNPHSFTGEDVLELQGHGGPVILDMLLDAVVQAGARLARPGEFSERAFLNDKLDLAQAEAIADLIEASSQQAAKQALNSLKGEFSNKIHELVEQLIHLRMYVESAIDFPEEEIDFLSDGIVEGKLNDVIDQTDAVLAQAQQGALLRDGMKVVIAGRPNAGKSSLLNALAEKDIAIVTNIAGTTRDVLREHIHIDGMPLHIIDTAGLRDSPDHVEQIGIERAWGEIESADRILLLIDTTDNSQLDVNVHWPEFTSNAAYAKKLTVIYNKIDESGFSTTNHTSDAPYQTLPLSAKTGAGLDTLKAHLKSVMGFQSTTEGGFSARRRHIHAIEQAQNYLLTGREQLQLHTAGELLAEDLRAAQNHLSEITGAFTPDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNE_NOSS1
Sequence: MPKQIIIAEQHQIAAVFSEDQIQELVVATGHHQIGDIYLGVVENVLPGIDAAFVNIGDPERNGFIHVTDLGPLRLKRTAAAITELLAPQQKVLVQVMKEPTGTKGPRLTGNITLPGRYVVLMPYGRGVNLSRRIKSESERNRLRALAILIKPAGMGLLVRTEAEGKPEEAIIEDLEVLQKQWEAIQQEAQSTRAPALLNRDDDFIQRVLRDMYGADVNRIVVDSSTGLKRVKQYLQNWSGGQTPQGLLIDHHRDRSPILEYFRINAAIREALKPRVDLPSGGYIIIEPTEALTVIDVNSGSFTRSATARETVLWTNCEAATEIARQLRLRNIAGVIVVDFIDMESRRDQLQVLEHFNKALRADKARPQIAQLTELGLVELTRKRQGQNIYELFGDTCPACGGLGHTVRLPGETENRLPTPAAEVPERFVSLPTREPRLPTARTTEPRETYDGFGEAFENDSDLGALNLINHPSYQELNDNNKRRARTRRSRIGINGTNGKDEQRITANPLAFISESDLDLDGDVELSAPPELPTPNLGKSGWIERAERTKVIKTEPVKPVVEPPEIRTVEMTPEEQDIFALMGISPLIKLEQEVKNPKSVIINIVQPGQTPTIPTEITPEPVAKVTPSVEVNTPKVKLESKSVSVAATEPIKLTETMEESEVNAASTANRRRRRRSSASDSDTGEDS
What is the function of this protein?
Endoribonuclease that plays a central role in rRNA and tRNA processing and mRNA decay.  Has been shown to act on 9S rRNA (the precursor of 5S rRNA).
What are the official names of this protein?
Ribonuclease E, AnaRne, RNase E.
What is the protein family that this protein belongs to?
Belongs to the RNase E/G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUCS_BEUC1
Sequence: MRLVIARCSVDYTGRLTAHLPLATRLLLVKADSSVLVHSDGGSYKPLNWMSPPCTLRVAEPDDDDVGRGVREVWTVQNAKSDDRLVVRIHDVLSDSSHDLGVDPGLVKDGVEAHLQALLAEQIDLLGSGHVLVRREFPTAIGPVDILARSAAGETVAVEIKRRGDIDGVEQLTRYLELLGRDPLLAPVQGVFAAQEIKPQARVLAQDRGIRCLVLDYDAMRGLDDVDSRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_CHLCH
Sequence: MPTHSLFLLSLGCSKNTVDSERLLAQAAAAAIRSVERVDEADTILINTCAFIEDAKKESIEEMLAALDKKREGVVKQVFVMGCLPELYRRELQEELPEVDAFFGTRELPQILASLGARYRSELFDERLLLTPSHYAYLKISEGCNRICSFCSIPKIRGRYQSQPLEQLLREATRLQQQGVQELNLIAQDISLFGYDTTGHSQLNELLLRLSDMDFLWIRLLYAYPVNFPLEVIDTMRDRSNICNYLDIPLQHCNDRILRAMKRGVTKADTIRLLHEMRQRNPNIRLRTTMLVGFPGETRAEFEELLDFVEEQRFDRLGCFPYNHEEHAPSAMLEDLLSIEEKEERVSELMELQEAVAESLNREFEGKEIEVVVDSFVEEMAFCRSEYDAPEVDNECLLTFGAQNIQAGNFYRALINDSSAHELYGEIVQERSAGNSPQ
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIT_METM5
Sequence: MIQDSEFFRMEGVPITKEEIRAVSIGKLNLDPEDIVLDIGCGSGGMSVEIAKRSKFVYSIDNSEDAKNTTSINLKKFKIENCEVFHGDAKDLISKFDFNKVFIGGTQNIEQTLEILKEKKIEKVVANTIVLENSVKIITKFEELGYNVDFVNLSVSYGKKISSGHIMLSKNPITIITATLK
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: DNAK1_THEVB
Sequence: MGKIIGIDLGTTNSCVAVLEGGNPVVIPNAEGGRTTPSIVAFGKSGERLVGQLAKRQAITNAENTIFSIKRFIGRRWEETAQERARVPYACVPGRDGMVDVQIRDRTYTPQEISAMVLQKLKQDAEAYLGEPVTQAVITVPAYFSDAQRQATKDAGAIAGLEVLRIINEPTAASLAYGIDKQDQDQTILVFDLGGGTFDVSILQLGDGVFEVRSTAGNNHLGGDNFDECIVDWLLACFKEQEGIDLSKDKMALQRLREAAEKAKVELSGTLSTSINLPFITADETGPKHLEMELTRSKFEELCAHLVQATLEPMQQAIADAGLTVEEIDRVLLVGGSTRIPAIQELVKQFCGKNPDRSVNPDEAVAIGAAIQGGILGKETTVKDLLLLDVTPLSLGLETLGGVFTKIIERNTTLPTSKTQTFSTASDGQTVVEIAVYQGERPIAKDNKQLACFELTGIAPAPRGVPQIDVTFDIDANGILSVSAVDRATGRQQSVRITNRGGLSSMEIERMRQEAQIYAQVDQIKKEIAELRNQADALLYSYESTIKNHGITLSPELRARIEPVVQSMQAAMVDDNITPDEIRKRMEALQQALVTLGSVVYQQTAGGSMMTSTPTMGRATMSSQATQVLDSEATIISDNEETVVSDYEAVD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK1, HSP70-1, Heat shock 70 kDa protein 1, Heat shock protein 70-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: COC2G_CONCL
Sequence: DVCDSLVGGRCIHNGCYCERSAPNGNCCDTAGCTVLWWCPGTKFD
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation (By similarity).
What are the official names of this protein?
Mu-conotoxin-like Cal 12.1.2g, Conotoxin CalTx 12.1.3F.
What are the subcellular locations of this protein?
Secreted.
Protein: RGPD4_HUMAN
Sequence: MSCSKAYGERYVASVQGSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDPRAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMHAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLLNLSRGKQDFLKVVVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLIHRKAVPGNSAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGSGLNSFYDQREYIGRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHVTFAILDAVNGNIEDAMTAFESIKSVVSYWNLALIFHRKAEDIANDALSPEEQEECKNYLRKTRGYLIKILDDSDSNLSVVKKLPVPLESVKEMLKSVMQELENYSEGDPLYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLLKMIRQEVKAIKEEMQELKLNSSKSASHHRWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKESEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGKPRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQQLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTGPTLEWDNCDLREDALDDSVSSSSVHASPLASSPVRKNLFHFGESTTGSNFSFKSALSPSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEKVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHTITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFGSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNASLKSNNSETSSVAQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPMEESSINYTFKTPEKEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLREAEATSAVLMEQIKLLKSEIRRLERNQEQEESAANVEHLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQGEE
What are the official names of this protein?
RanBP2-like and GRIP domain-containing protein 4.
Protein: LDH1_CLOAB
Sequence: MKKNTKISVIGAGFVGSSTVFALMNGGLASEIVIVDVNKDKAEGEAMDLSHGAAFVKPVVVKSGDYKDTEGSDIVIITAGAAQKPGETRLELINKNYNIFKSIVPEVVKYNPNAILLVVSNPVDILTYITYKLSGFPKSRVIGSGTVLDTSRFRYMLSEHFEIDVRNIHTYIMGEHGDSEIATWSLTNIAGMDVNEYCEASCKKCDGSLKYKIYDDVKNAAYHVIEKKGATYYAVALAVKRIVEAILRDENSILTVSSLLEGQYGIKDVYMGVPSIVGINGVKDIIEVPLNDEEKNNLTDSAKTLKESLDSIF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSX_MYCSS
Sequence: MTLTSPPRTRADSRYSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVDDYIFNFPDTSFAWAFVLALLAGALAARKRIAWWILLLYMVAAAGWNVADLLTGDESVVDEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAVGVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAPGVMGASVGGAEAFRAAGLSAIQLGDEAILLPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADAWRDTETERGFSMALGRLGDPADSDCLLVEAVQGGNGGQERSDPGDGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIELMVSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKLKALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAAIDLGDLIAATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIRDTLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHEAVSEALGEHIDAATELPTLRKLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTQKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPSG_STRPE
Sequence: MAELSLAELREIMRQSLGEDEVPDLADADTVTFEDLGLDSLAVLETVNHIERTYGVKLPEEELAEVRTPHSMLIFVNERLRAAA
What is the function of this protein?
Involved in the biosynthesis of aklanonate which is an important precursor common to the formation of the clinically significant anthracyclines such as carminomycin, daunorubicin (daunomycin), rhodomycin, aclacinomycin T (aklavin) and aclacinomycin A (aclarubicin).  These compounds are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.
What are the official names of this protein?
Anthracycline acyl carrier protein DpsG.
Protein: RAB18_PONAB
Sequence: MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREEGQGGGACGGYCSVL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts (By similarity).  Also required for maintaining endoplasmic reticulum structure (By similarity).  Plays a role in apical endocytosis/recycling (By similarity).  Plays a key role in eye and brain development and neurodegeneration (By similarity).
What are the official names of this protein?
Ras-related protein Rab-18.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Apical cell membrane. Lipid droplet.