PharMolix/UniProtQA huggingface dataset:
Protein: TNAA_HAES1
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYRDEAILKAGMNLFLLDSEDIFIDLLTDSGTGAVTQDMQAAMLRGDEAYSGSRSYYALANAVKEIFGYEYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRNKMVVFSNYFFDTTQGHSQLNGATVRNVYIKEAFDTDVDHDFKGNFDLEKLEQGILEVGANNVPYIVCTITCNSAGGQPVSLANMKAMYQIARKYDIPVIMDSARFAENAYFIQQREAEYKDWTIEQITYESYKYADALAMSAKKDAMVPMGGLLCFKDNSMEDVYNECRTLCVVQEGFPTYGGLEGGAMERLAVGLRDGMRQDWLAYRISQIEYLVQGLEKIGVVCQQPGGHAAFVDAGKLLPHIPAEQFPAQALACELYKVAGIRSVEIGSLLLGRDPKTGQQLPCPAELLRLTIPRATYTQTHMDFIIEAFKRVKENAKNIKGLDFTYEPKVLRHFTARLKEI
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: CHR1_BOMMO
Sequence: MAFRGIVVLASALFVQSALSQCVGRAGPGLGGYRGGWDGFGYDGLGYDGAGYGWNGRLGCGGLGDDIAAASALGASHGGTLAVVTSSAAPTGLGIASENSYEGGVGICGNLPFLSTASIAGELRTGGTGGIDYGCGNGAVGITVESVISPAINYAPAGAPLGRSFNRGCGCGAANPY
What is the function of this protein?
This protein is one of many from the eggshell of the silk moth.
What are the official names of this protein?
Chorion protein ERB.1.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: NUOI2_GEOSL
Sequence: MPILTDFKAIATGLFVTWKHIFRRPVTVEYPEVKRTPAPRYRARIVLTRDPDGGERCVACYLCSAACPVDCISMEAAEGEEGRRYARWFRINFSRCIFCGLCAEACPTLAIQMTPDYEICERDIMELVYEKEDLLIDGCGKDAGYNFYRHAGIGVAQPRGAGECEEEPVDVRGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBL7_HUMAN
Sequence: MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP
What are the official names of this protein?
Ubiquitin-like protein 7, Bone marrow stromal cell ubiquitin-like protein, BMSC-UbP, Ubiquitin-like protein SB132.
Protein: KCY_SHEPC
Sequence: MSERAPVVTIDGPSGAGKGTISQLLAQHLGWQLLDSGAIYRVLALAAIHHDVELENEESITLLAAHLDVKFLTGNDKDPVQVILEGEDVTTDIRTQECSNAASKVAAFPRVREALLRRQRAFRTAPGLIADGRDMGTVVFPTAPAKLYLTASAEERAQRRYNQLQDKGFDVNIERLLSEIIERDERDMNRPVAPLVPAEDAFVIDTSGKGIDEVLELALKYINEKLSSAN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEU29_SCHPO
Sequence: MFVVKTAVLLFFALFIGNTYAYTYSLDRIQALKFSSESSNVDDGPRLHCKGPACSSHSNDLAICQHNQLNVAPHLLKWTCVWPNQSSHVEVIDYNIECKKTVALSMDSITKTCILNYKLEWTYSGVLLHRPWKLFSLKPFTAAFVLLLAASYLATACFRMLGYLGTPRSRFHDNRRWNEQKFMELAVSAVEEQLSNGIQLFSNVKQRVPVPVLDESV
What are the official names of this protein?
Meiotic expression up-regulated protein 29.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: VP91_NPVEP
Sequence: MSDVVLLVLAIIFIIIFVLIYCTIFFEFDETTFSKRLHVLTEYAKRTNAEHPTPDVLGHVSDVYEHTYIVTWFNTNDLSVYHETVHDDTIEVFDFLEQKFSPAKSTVAQRVAPSASDPNAFVLTGDKSEVKMHCPQHFNFDYNQLKCVPINPCDTRAPGLYAMDEHLLDALVHSQHLDKDYTINAHLQHPTLYLRCLADGSYVVQECPDNYTFDAATSECKVNELCQGRPDGYVLDYFPETLLVNEFVECYESKHVVKQCPEQHVFDRQLMTCVQAHPCAFNGAGHTYITADIGDTQYFECLNNQESQLITCINRVRNTDGQYACSGDARCANLTDGTGQLVHMHVDDTFEYASGQLVCDNFEVISEIDCNTSDVLTNMLFLQKFKLETEFPRQVFDNGECVPATFNNVRVLNDTFPIQNVPNDYNIDMQTSIIGLTDMIPKLLAGDDLDDTFGQNVVLARDVGAVGLNPVTAEPIDCLGTQLFDVLDASRANICTESGDGVLKTLKFENGTFLSVFRDNLTGSDIDYKRFCAISYENSLKIVKSDHFERRILTNILQSDVCADLYTTMYQKYTTLARKYTTTPFQYTYTFVKPPPNIVVYAKNIQLKNATISKPAFDPFANKQIDNKNNLAKPLFDPFKNAVWYSEPDGGDGDHWGPDLPPPVQPDSEPDESEPEPEVSPLILDKKDLFYSCYYELPSFKLTSCYAENDVIIDAITDLRNNVTVDAECEPAKDLHYVLNAYAYTGNGVGCRSVFNDDGVAVIKEPIPSYVFANLNTQSNDGVHYNRHVHVKDGRYMACPDHLYDDVEFRCNVEADKLYYLDNMQF
What is the function of this protein?
Probable capsid-associated protein.
What are the official names of this protein?
Capsid-associated protein Vp91.
What are the subcellular locations of this protein?
Virion. Note=In virions, associates with the capsid and maybe also with the envelope surrounding the capsid.
Protein: SDHE_PSE14
Sequence: MVEDVELNRLYWHSRRGMLELDVLLVPFVREVYPHLNDVDRDLYRRLLTCEDQDMFGWFMQRAESEDAELQRMVRMILDRVQPK
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_LEPBA
Sequence: MKEKKLWGGRFDAAPSSLMIRIGESISFDQELYRHDIEGSISHSRMLRRIGILSESEQRKIETGLGQIKKEIDSGKFEFKIENEDIHMSIESRLTELLGDLGKKLHTGRSRNDQVSQDVRLYIKSEMHSILILVYDLLTVWLKKAEAHTKTIIPGYTHLQIAQPIRASHYFLSHFWANVRDFEDFYSAFERADELVLGSGALAGVNYETDREYLRKDLNLARMSENSMDAVSQRDHIFKFLFASSQFMVHASRFCEEIILYTSQEFSYFKLPDHLTTGSSIMPQKKNPDVAELIRGKAGRVIGNLTHLLVMLKGTPLSYNRDFQEDKIPLFDTVKQIKICTEGIRDMVEGIQIFPENATRSLRNGFSTATDLADWLVSAKGIPFRSAHEIVGELVKHCSMKGYDLFTIPSGERGQIHAVLTDPGYEAAISLETSCDKKDVFGGTALPRQKEQIKRAKAKLNELTKKLKQIESKGKKTI
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V1R48_MOUSE
Sequence: MNENSRLHTHSNIRNTFFSEIGIGISGNSFLLLFHIIKFFRGHRPRLTDLPIGLLSLIHLLMLLVAAVIATDIFISWRGWNDIICKFLVYLYRSLRGLSLCTTSMLSVLQAIILSPRSYCLAKFKRKSSHNISCAIIFLSVLYMSISSHLLISITATPNLTMNDFLYVSQSCSLLPLSYLMQSIYSTLLVLREVFLIGLMVLSTSYMVALLYMHRKQAQNLQGTSLSLKASAEQRATQTILMLMTFFVLMSIFDSIVSCSRTMFLDDPTSYSIHIFVMHIYATVSPFVFISTEKHIVNILRG
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social and reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 48, Vomeronasal type-1 receptor A3, Vomeronasal type-1 receptor A6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_CUTAK
Sequence: MEGPGLEFTEAIIDNGKLGKHVVRFEAGLLAQQADGSAAVYLDGDTMLLSATTAAKTPRDSIDFFPLTVDVEERMYAAGRIPGSFFRREGRPSEGAILACRLIDRPLRPSFVKGLRNEVQVVVTVMALNPAVYYDVVAINAASMSTQLAGLPFSGPIGGVRMALIDDQWVCFPSVDQRKESTFDMVVAGRVLADGDVAIMMVEAESTPATWGLVRGGRTAPTEEVVATGLEAAKPFIKVLCDAQVALAAKLPKETYDFPVFKDYEDDVYAAVEEKAADELSRIEQIAAKLERQEAESELKARIKAELAETFPEREAEISGAFKAVMKKIVRKRVLDEGVRIDGRGPRDIRSLSAEVGIIPRVHGSALFQRGETQILGVSTLNMLDMEQKLDTLSPENTRRYMHNYNMPPYSTGETGRVGSPKRREIGHGNLAERALIPVLPTREEFPYAIREVSEAIGSNGSTSMGSVCASTLALLNAGVPLRASVAGIAMGLMSETDEDGKTKYLALTDILGAEDALGDMDFKVAGTSEFVTALQLDTKLDGIPADVLAGALKQAKEARTAILEVMNEAIDSPDEMAPTAPRIITVHIPVDKIGEVIGPKGKMINQIQDDTGANISIEDDGTIFIGADNGDSAESARSMINAIANPQMPEVGERYLGTVVKTTSFGAFVSLLPGKDGLLHISKMRDLNDGKRVEAVEDVLSVGQKIQVEIAEVDDRGKLSLVLASDEDDADE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXP2_SCHPO
Sequence: MTHNTMLQRFNGLLEPTHLYIVSVVAYSACNRPDKISGIAKEAMEHVGPSIYPKLREALVKSSPLVGFPRTINSLREMTTNIPPPFPDEFARAADADIDTGKRGKIYFEKTYGKVTQRVLRSMQSSSLDLANIALDYAYGKVLSFNEVVSPLETSLMIIAALVPQDVNPQLRGHLKGALNHGATKEQVMSARNIALEISKECGIQFKGDIETL
What is the function of this protein?
Probably involved in peroxisome formation or maintenance as well as in amino acid metabolism.
What are the official names of this protein?
Peroxisomal protein 2.
What is the protein family that this protein belongs to?
Belongs to the PXP2 family.
What are the subcellular locations of this protein?
Peroxisome matrix. Cytoplasm, cytosol. Nucleus.
Protein: PT310_ARATH
Sequence: MSSHARGKELIPLLSFSHQKKQPNLSISSTTKMNKKNPDQKSDMSSSSSSPKKQTLFISSLIILWYTSNIGVLLLNKFLLSNYGFKFPIFLTMCHMSACAILSYVSIVFLKLVPLQYLKSRSQFLKVATLSIVFCASVVGGNISLRYLPVSFNQAVGATTPFFTALFAYIMTFKREAWVTYGALVPVVTGVVIASGGEPGFHWFGFIMCISATAARAFKSVLQGILLSSEGERLNSMNLMLYMSPIAVIALLPVTIFMEPDVMSVTLTLGRQHKYMYILLLVNSVMAYSANLLNFLVTKHTSALTLQVLGNAKGAVAVVISILLFRNPVTVMGIGGYSITVLGVVAYGETKRRFR
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At3g10290.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CPEB1_PONAB
Sequence: MLFPTSAQESSRGLPDANDLCLGLQSLSLTGWDRPWSTQDSDSSAQSSTHSVLSMLHNPLGNVLGKPPLSFLPLDPLGSDLVDKFPAPSVRGSRLDTRPILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSLTGGGPRDPLKMGVGSRMDQEQAALAAVTPSPTSASKRWPGASVWPSWDLLEAPKDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLNPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVTAAFVEIKTTKFTKKVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKNRDSS
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons.  Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR.  In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation.  Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses.  Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation.  Induces the assembly of stress granules in the absence of stress.  Required for cell cycle progression, specifically for prophase entry.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 1, CPE-BP1, CPE-binding protein 1, CPEB-1.
What is the protein family that this protein belongs to?
Belongs to the RRM CPEB family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasmic granule. Synapse. Membrane. Postsynaptic density. Cell projection, dendrite. Note=Also found in stress granules. Recruited to stress granules (SGs) upon arsenite treatment. In dendrites. Localizes in synaptosomes at dendritic synapses of neurons. Strongly enriched in postsynaptic density (PSD) fractions. Transported into dendrites in a microtubule-dependent fashion and colocalizes in mRNA-containing particles with TACC3, dynein and kinesin. Membrane-associated. Colocalizes at excitatory synapses with members of the polyadenylation and translation complex factors (CPSF, APLP1, TACC3, AURKA, SYP, etc.) including CPE-containing RNAs (By similarity).
Protein: CMC4_LACTC
Sequence: MTDPCKPQACAIQGCLTKTGFDESKCSHLIDSLYECCSKFYNERGADARTPCCPVPSLLRLKLEQRACGPLDAKRVR
What are the official names of this protein?
Cx9C motif-containing protein 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the CMC4 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Imported into the mitochondria via the mitochondrial disulfide relay system.
Protein: RL20_BORA1
Sequence: MPRVKRGVTARARHKKVIAAAKGYRGRRGNVFRIAKQAVMRAGQYAYRDRRNKKRTFRALWITRINAAVREQGLSYSVFIAGLKKAAIELDRKVLADLAVRDKAGFAAIVQQAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: IWS1_GIBZE
Sequence: MSERDSPVGEHTKEPVNDGQEQEYEDAVAAADSDHDSDALSEVDEDQFEDYDPETANIEDRPVDIDEDVARTLKATKRKRTEGEAPKKPREGRRDKKRRDRDEDVEMDDAEDGSKKSRRSRRVAVDGERRQKSKAATPEPENEDHLSPEERRKRAIDRALDAAIKKPSGQKRKKKDEIDLEAEIDDLLADLKVRMEGACQSDNQAREAGQPALHKLKLLPEVTAIMNRNNVQHEVLDPDTNFLQHVKFFLEPLNDGSLPAYNIQRDIFNALAKMNIEKEALLSSGIGKVVVFYTRSKKPEPSIKRIAQRLLGEWSRPILNRTDDYKKRQIETRDYDYDAAKMAQRQKTNSQFSLSQRPAPNTKEAERERLLAPSRGNNSARMVNLPSSYTVAPQSTFMGSQGSGHRPLGAGGMEAFRKMTQKSKKRAN
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BR2A_ODOHO
Sequence: GLLDSLKNLAINAAKGAGQSVLNTLSCKLSKTC
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacterium S. aureus ATCC 25923 (MIC=18 uM) and the Gram-negative bacterium E. coli ATCC 25726 (MIC=36 uM).
What are the official names of this protein?
Brevinin-2HSa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RPPH_BURP1
Sequence: MLDREGFRPNVGIILLNAHNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLLPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRTDKSRGPRAPRYPRVANGHAASEAPAAIDTSAVCSEVEPGANALDETPPRVSLRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RFCL_METB6
Sequence: MEWAEKYRPEHLADIVGNTSAVRQMADWAKTWTARSKPLLLYGKPGIGKTSSVYALARDMNWDVIELNASDQRTAAVIERIAGAGSTTASLTGSARKLIIMDEADNLQGTADRGGAKAILECIKNARQPIVLIANDLYGLAAELRLRCEPVQFRALPARSIAPRLKYICSSEKIACSESAVHEIAESAEGDMRSAVNMLYASAIGRQSLDGKNVHTSQKDERVSIFSLVTAVFGKTSDEELIRLSRDVDEFPEDIEQWVEGSVHTITDPAGLGLAYRSLSRADEYIGYTYRRQYHTLWRYATAVMLLGVADASAGKGIHSRILPPERWQKMSVAKKQKAIRAAVLSRLAATMQLPQATLREKYMDIITLLVDLDPETFARELALDADGLNFFLNDKSRAQEILKSLAKVEREKEPEPKKKGRKKAESPAKDADPAPAVDPVPKEELPVKSAPEERPADPPAPEEPGRKTVAHNQSTLFDGF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: DCDA_BACTN
Sequence: MKGIFPIDKFRTLQTPFYYYDTKVLRDTLSAINQEVAKYPSYSVHYAVKANANPKVLTIIRESGMGADCVSGGEIRAAVRAGFPANKIVFAGVGKADWEINLGLEYGIFCFNVESIPELEVINELAAAQNKIANVAFRINPDVGAHTHANITTGLAENKFGISMQDMDRVIDVALEMKNVKFIGLHFHIGSQILDMGDFIALCNRVNELQDKLEARRILVEHINVGGGLGIDYGHPNRQSVPDFKSYFATYAGQLKLRPYQTLHFELGRAVVGQCGSLISKVLYVKQGTKKKFAILDAGMTDLIRPALYQAYHKMENITSEEPVEAYDVVGPICESSDVFGKAIDLNKVKRGDLIALRSAGAYGEIMASGYNCRELPKGYTSDELV
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: SWT21_CANGA
Sequence: MNQANVKNTTFHSMTSVSYNLSPYCSTGTTFRKQPLYRIWETESSTSADLSQKLNYMFPKLGLSESQTSLKDKDVTKDVVCQDIHWSVDATSLFTINSDYGIRQYLIPDPKSDQTLLNPYSRIFAHESVLSSDISPRYSLYEGSSEPLANSILIGAKNVPIKLVDLNDTNNLSTIRSYDISNLENEKFETPYVLKYHRESLFLSGTVRNKVNVYDVNRREPVNTLTYSRRSKCGTQSYKSIISCLDDSFSDNQVRYCGSYKNQVFIIDLRGKTLQLLNNLQGNGARGCYQIINSDNGSYLYVLQRYSSRIEILDHRRPDRPVNHLELPGRSDFQKLKACYNGSFQVGSPLGKGQILSWDKSTIESGGITRENQVVQCQPDILYNVPQCKSMRINIIKTSSDATAISYSGDTAGIALLQR
What is the function of this protein?
Involved in mRNA splicing.  Helps to stabilize the U1 snRNP-5' splice site interaction (By similarity).
What are the official names of this protein?
Protein SWT21.
What is the protein family that this protein belongs to?
Belongs to the SWT21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_TROW8
Sequence: MEDLYGILGVDHDASVDEIRRAYRRLARELHPDINPDSADRFKAVTHAYNILSDPEQRQRYDRHVSGGFSSDFNLSDLFQSFFDTSAEFQRGSDLLVNIDIDLKTAIYGGSQVVKIDSLVVCDVCNGTRSEPGYKAEVCFDCNGSGVVRGEVRTTLGNLITQNTCSKCRGNGERIDHPCRRCYGNGSRSAPRDITINIPPGVETGMRIKIPNMGNAGGAMPGDLYVDCKVKEHPYFLRDGQDLYCRLDISLVDALLGTKVKIDSLDGELAVVIPALSQNRDVIRIANKGAVTLRGGKGDLCIVLNVLLMQKLDPEHRALLKKIMPNPPKPKLAKRTSGFFSWLKNKFT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_CAEEL
Sequence: MGIDINHKHDRVARRTAPKSENPYLRLLSKLYAFLARRTGEKFNAIVLKRLRMSRRNRQPLSLAKLARAVQKAGNENKTVVTLSTVTDDARLYTVPKISVAALHVTEGARARILAAGGEIITLDQLALKSPKGENTVFLQGPRSAREAEKHFGPAPGVPHSHTKPYVRSKGRKFERARGRRASRAYKN
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP9_YARLI
Sequence: MTTPDLEDKSFDSFGLDDRLLSGLAACDMKQPTLIQNTTIPLALDKGVDITAKAVTGSGKTVAYLLPIFELMLRAEKEKRDIQTALIVVPTRELCEQVSKVITKLTQFCPHLKSLNVTQQLGDDVISSLLEEKPSIIVGTPSRLLKYAKEMDCSKVGYLVIDEADLLLSYGYKEDLIELSEMLPKTKHTFIMSATLNKESDLMKQQFCRSTVASVAVTAAEEERKLLQYYVKCSERDKFLLAYVMFKLQLVKGKTIVFVNEIDRCYRLRLFLEQFGIKACVLNSELPIASRLHIVEQFNKGVFNLLICTDEANKLAEASKSASKQTKEVSRAHEYSSTRGLDFMNVAFVLNFDLPLSSRAYVHRVGRTARANKAGTALSFVVPADQWGKDKVAKLDTAKRDEKVLKKIIKNQESQNMEIKPYSFDMKQVEGFRYRMDDAFRAVTTVGVREARVKEIKTELLNSERLARHFDENPDDLKALRHDKELHTSKVQAHMKRVPDYLLGRKGKLDPNVFVPFRKDDNKIHKKYTKKKKGGDPLKFKKRK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KDSB1_HYDCU
Sequence: MSFIVIIPARYESSRLLGKPLMDIQGKPMVEWTWMQAKKSGATRVVIATESDRVKAVCESFGAEVCLTSERHESGTERIAEVASLLGLNDDDILVNVQGDEPLLPPDLIHQVAEGLETHPNTLMATLCEPILDVETVFDPHAVKVIRDCNNYALNFTRAPMPWSRDTFGSEPKTLPGNWPYRRHIGLYAYRSGFVKRYVEWPVCALEQVEKLEQLRVLWHGEKILVLDALCEAGVGVDTEQDLIKVRKIMANLNPDGAL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase 1, CMP-2-keto-3-deoxyoctulosonic acid synthase 1, CKS 1, CMP-KDO synthase 1.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL6_FELCA
Sequence: MTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGDATSNRLPLTSADKMEELIKYILGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKDGCFQSGFNQETCLTRITTGLQEFQIYLKFLQDKYEGDEENAKSVYTSTNVLLQMLKRKGKNQDEVTIPVPTVEVGLQAKLQSQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_CHLL2
Sequence: MSEQSKCPVTGRTAGHPVAGGGMSNRDWWPNQLPLDMLHQHSSLVNPMGEAFRYKEEFKKLDLGAVKKDLYALMTDSQEWWPADYGHYGGLFIRMAWHSAGTYRTSDGRGGGGTGNQRFAPLNSWPDNANLDKARRLLWPIKQKYGKMLSWADLMILAGNCALESMGFRTFGFGGGRVDIWEPEEDIYWGKEVEWLGSNRYSGERDLENPLAAVQMGLIYVNPEGPDGNPDPVAAGRDIRETFARMAMNDEETVALVAGGHTFGKCHGVGDPNLIGPEPEAAPIEEQGLGWKSGYGSGKGDETMTSGLEGAWTPDPIHWDMGYLGMLFKYEWELTKSPAGAWQWKPKDVAEEDLAPAAHDPSKRVPTMMTTADLAMRMDPIYGPISRRYYEHPDQFADAFARAWFKLTHRDMGPKSRYLGAEVPAEDLIWQDPVPAVDHELITEGEIAELKMRILASGLPIPELVSTAWASASTFRGSDKRGGANGARIRLAPQKEWEVNQPEQLQRVLHELEKIRDTFNGEQSGGKRVSLADLIVLGGCAAVEEAARRAGHDVTVPFAPGRTDASQAETDVESFAALEPLADGFRNYAKRKYSVTPEEMLIDRSQLLTLTAPEMTVLVGGLRVLGINFRQSPHGVFTRHPETLTNDFFVNLLDMGTEWKPVSHEHDTFEGRDRKTGEPSWSATRVDLIFGSNARLRAIAEVYGSDDAQEKFVHDFVAAWDKVMNLDRFDLS
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.