PharMolix/UniProtQA huggingface dataset:
Protein: RNCL_ASPCV
Sequence: MVAIKNLVLVALTAVTALAMPSPLEERAATWTCMNEQKNPKTNKYENKRLLYNQNNAESNAHHAPLSDGKTGSSYPHWFTNGYDGDGKILKGRTPIKWGNSDCDRPPKHSKNGDGKNDHYLLEFPTFPDGHQYNFDSKKPKEDPGPARVIYTYPNKVFCGIVAHTRENQGDLKLCSH
What is the function of this protein?
Clavin has the same substrate specificity as alpha-sarcin.  It is specific for purines in both single- and double-stranded RNA.  Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bond in the 60S subunit of ribosomes.
What are the official names of this protein?
Ribonuclease clavin.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease U2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUFE_ECO8A
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRAEDRSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_ECO7I
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: MUTL_ECOL6
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYSPAPASGSRPAASWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEVPVCAQPLLIPLRLKVSGEEKSALEKAQSALAELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MATRX_HAPV1
Sequence: MAYSKGVSGTLSDYTHLRTLPALLSVVFVIAGLYQFGGISDVTITWLSNYTLTSTHAMGASIGAYALAFASSETKQFDNYQDFEKVLIAAGPAVILGYEYIQPVTDLINTTSNAGPIAAFVVTVVAWGVAVR
What is the function of this protein?
Envelope protein that may play a role in host-cell attachment and viral genome entry.
What are the official names of this protein?
Matrix protein, Mtrx, Virion protein 3, VP3.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein.
Protein: ANMK_YERPS
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDERMVAQQASYTHPIPLQLKKDILGMCQGQSTTLSAVGKLDAQLGILFAEAVLALLAKEGLSAQDITAIGCHGQTVWHEPLGEPAFTMQLGDNNRIAAMTQIATVGDFRRRDMAYGGQGAPLVPAFHHALLAHATEKRMVLNIGGIANLSVLLPDSPIRGFDTGPGNMLMDAWIWRNCSLPYDKDACWALSGHVNQPLLEQMFNDPYFRLPAPKSTGREYFNAAWLDKQLARIPGVTAEDIQATLAELTAVSITEQVRLAGGCDRLLVCGGGARNPLVMARISALLSGTEVCTTDDAGIRGDDMEALAFAWLAFRTLSGKPGNLPSVTGASRETILGAVHPVSSW
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CE024_MOUSE
Sequence: MMHPVAGSNPAFCGPGKPSCLNEDAMRAADQFDLYSSQQNKYSHTVSHKPMVCQRQDPLNETHLQPTSGRNIEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMMHSRVVHGLQETSGEVKPPSE
What are the official names of this protein?
UPF0461 protein C5orf24 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0461 family.
Protein: ATPA_YERPP
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGSIENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPYSGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHAELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TIG_RHOP5
Sequence: MQVKETVTDGLKREFQVTLAVSDIGSQVDARLDELKDKVRLNGFRPGKVPLSHLKRTYGRSVTAEVLEKLIRETNDNIFTERGFRLATEPKITMPTEAKEVEDVLAGNADLNYTVAVEVVPEIQLVDFKTISVEKPVVEVGDSDVDDAIKRIVEANRGYDDKGEGATAASGDRVTVSFKGSIDGTPFDGGSAEGIPVVIGSGTFIPGFEDQLIGIAVGETRTIKATFPTNYATAELAGKAAEFETTATLVEAPKDTPADDEFAKTLGLESLDKLKEAARGRLAAEYAGVSRQRVKRALLDRLDEAHQFEAPATLVEQEFEALWRSIVGEMTSTGSTFESENTTEDAAKEEYRKIADRRVRLGLVLSEIGEKNKIQVTDDEVSRAVMERARQMPGREKEVWEFYRKTPEAVAQLRAPIFEDKVVDFILELATVTEKPVSKEELYKDDDADKSAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PSBT_CALFG
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ISCA_PECCP
Sequence: MSISLSESAAQRVSAFIANRGKGLGLRLGVRTSGCSGMAYVLEFVDDLNDGDTVFEDKGIKVIVDGKSLVYLDGTELDFVKEGLNEGFKFNNPNSSGECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: HPPK_MYCTO
Sequence: MTRVVLSVGSNLGDRLARLRSVADGLGDALIAASPIYEADPWGGVEQGQFLNAVLIADDPTCEPREWLRRAQEFERAAGRVRGQRWGPRNLDVDLIACYQTSATEALVEVTARENHLTLPHPLAHLRAFVLIPWIAVDPTAQLTVAGCPRPVTRLLAELEPADRDSVRLFRPSFDLNSRHPVSRAPES
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: YMCF_EMEND
Sequence: MDIIGSGFIRFKYNYIIIIIINIIPELMPLKSVNFLIITSLYAWKIPK
What are the official names of this protein?
Uncharacterized 5.6 kDa protein in COX1 intron, URF-F.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SELA_METSB
Sequence: MEGSSSGRLRDLPSVDAVLKAPAALAMLERFGRAASTDAVRAALADARAAIAGGASHAPDAAVLARAAEASLEADELSNMRPLFNLTGTVLHTNLGRAVLAEAAIEAAVAAMRDPVALEFDLETGKRGERDDHVRALLCELTGAEDATLVNNNAAAVLLCLNTLAAGREAIVSRGELIEIGGAFRMPDIMARAGAKLVEVGTTNRTHLKDYRVALSAQTGVILKVHTSNYRIEGFTAEVGAAELAALAGQANVPLMNDLGSGTLIDLSRYGLQREPTVREAVREGSGLVTFSGDKLLGGPQAGFIVGARALIEAVNRNPMKRALRVDKIRLAAIEATLKLYRDPDRLAERLPTLRLLARPLAEIEAQARRLLPAAAVAVEPAYQVALRLCRSQVGSGALPLDTIESAGLIIRPTNGSRSLERLAGALRALARPIIGRIEDGGLLLDLRCLTDEAGFLSSLSALDADALA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y121_OSHVF
Sequence: MVKSRNTTTAHVHDVPRIMGGIKKLKLTKETAMAAGRKLKTLLAKVDAVEKVCVICMEPTYTKKTLAECDIEGGALRVTTMPCPTHYICDNCIRQEMEDKCPICRKDWPERRIIYGNEAKLYKYWLIDNDDIMILENNNDIDELTPEEEDHLLSDDESDNYVPRYTLDSLVEEVLSERSQMSNDRLMNDMIDNIAVNNAIDDDCIIIDDYIDLTI
What are the official names of this protein?
Putative zinc finger protein ORF121.
Protein: NIPA1_MOUSE
Sequence: MGTAAAAAAAGEGARGPSPAAVSLGLGVAVVSSLVNGSTFVLQKKGIVRAKRRGTSYLTDIVWWAGTIAMAVGQIGNFLAYTAVPTVLVTPLGALGVPFGSILASYLLKEKLNILGKLGCLLSCAGSVVLIIHSPKSESVTTQAELEEKLTNPVFVGYLCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQRALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAIYYVVFTTLVLLASAILFREWSNVGLVDFLGMACGFTTVSVGIVLIQVFKEFNFNLGEMNKSNMKTD
What is the function of this protein?
Acts as a Mg(2+) transporter.  Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+).
What are the official names of this protein?
Magnesium transporter NIPA1, Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NIPA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Recruited to the cell membrane in response to low extracellular magnesium.
Protein: PSA_STRSW
Sequence: MSTPFYVSPQQAMADRAEYARKGIARGRSLVVLQYADGIVFVGENPSRALHKFSEIYDRIGFAAAGKYNEYENLRIGGVRYADLRGYTYDRDDVTARGLANVYAQTLGTIFSSAAEKPYEVELVVAEVGETPEGDQIYRLPHDGSIVDEHGSVAVGGNAEQISSYLDQRHQDGMSLAEALKLAVQALSRDTNGTQREIPAERLEVAVLDRTRPQQRKFKRIVGRQLDRLLEADGATTEAESSAEEEDE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ2_THET8
Sequence: MAAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDPEKRRIYDTYGTTEAPPPPPPGGYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLRAELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIRVPGMGGQGNPPGDLLLVVRLLPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGFPGPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA
What is the function of this protein?
Does not influence ATP binding or hydrolysis nor ADP release.  Exerts influence on the interaction of DnaK with substrates; in the presence of DafA, DnaJ inhibits substrate binding, and substrate already bound to DnaK is displaced by DnaJ and DafA.
What are the official names of this protein?
Chaperone protein DnaJ 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAD1_SCHPO
Sequence: MEEFTLDRNSNVGNLIALAVLNKFDELARHGKPIIRANGVREWTTLAGVVIQKKMENEFICVCLATGVKCTPAGIIKNEQLGSVLHDCHAEILALRCFNRLLLEHCILIKESKKDTWLLEVADNGKFTLNSNLLIHLYVSECPCGDASMELLASRLENNKPWNLTVDSEKLMRGRADFGLLGIVRTKPGRPDAPVSWSKSCTDKLAAKQYLSILNSQTSLICEPIYLSCVVLYKKVIVKSAIDRAFGPFGRCAPLAEFGEKDNPYYFHPFTVLETDENFLYSRPLNQAEKTATSTNVLIWIGDKMQCTQVIHNGIKAGTKAKDVEKSQTLICRKSMMNLLHQLSQSLTNEKNYYEWKKLNIKRCQQKQILRNILKNWIPNGGNEFQWI
What is the function of this protein?
Deaminates adenosine-37 to inosine in tRNA-Ala.
What are the official names of this protein?
tRNA-specific adenosine deaminase 1, tRNA-specific adenosine-37 deaminase.
What is the protein family that this protein belongs to?
Belongs to the ADAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DDL_BRUA4
Sequence: MTGKHVAVLMGGFSSERPVSLSSGTACAATLEERGYCVTRIDVDRNVASVLAELKPDVAFNALHGPFGEDGAIQGVLEYLQIPYTHSGVLASALAMDKDRAKKVAAAAGVAVASSLLLNRFEIGTEHPMEPPYVVKPVREGSSFGVVIVKEDQTHPPQIISSAEWNYGAEVLVEKYIPGRELTCAVMGDRVMDVCEIIPVGHQFYDYDSKYVAGASSHVCPAKILPNIYQKIQTMALTAHRAIGCRGVSRSDFRFDDRFSDDGEVIWLEINTQPGMTPTSLVPDIAKAAGISFGELLSWMVEDASCLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MADL2_MOUSE
Sequence: MGSTMEPPGGAYLHLGAVTSPVGTARMLQLAFGCTTFSLVAHRGGFGGVQGTFCMAAWGFCFAFSVLVVACEFTKLHSCLRLSWGNFTAAFAMLATLLCATAAVIYPLYFTRLECPPEPAGCMVRNFRLAASVFAGLLFLAYAAEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHESRYGRYVATQWCVAVYSLCFMATVAVVVLSVMGHTAGLGCPFDRLVIVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPADCLRGSCPWDSQLVVAIFTYVNLLLYIVDLAYSQRIRFVPTL
What are the official names of this protein?
Myeloid-associated differentiation marker-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AROK_METAR
Sequence: MKSHGTAYGAGTIINAIAVWKGSAFAIDLKTHATVELRGDLIEGEIEGGGDSRLIERACELTLDKLGVDSGAKIRTTSEIPIASGLKSSSAAANATIIATCRAARQSVDPLEMVRIGVQAALDVGVSVTGAFDDACASMLGGVVLTDNREKALLKREVLESKVVVYAPDKKAFSAQTDVKKSRLIAPWVETAFDIAMRGDYRKAMALNGFLYCSALGFSAEPILAALELGVTGVSLSGTGPSYVALVSEEGEEADRLKKAWSAYPGRVFVTEVINEGAFLLEGEECRWNT
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_XANOP
Sequence: MTTPSPSDALLIAGKRYRSRLLTGTGKFKDLDETRLATEAAAAEIVTVAIRRVNIGQDPNAPSLLDVLPPDRYTLLPNTAGCYSAEDAVRTCRLARELLDGHNLTKLEVLGDERTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGIQNKYNLLEIIENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOB1_RAT
Sequence: MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKVKVSSSIQHPETPLHISGFHLPSKSKALQETVDHGPPADGSENLEFSSFMFWRNPLPNIDHELQQLLIDGREEEEEEEEEEEEEDELEDSDDDGGGWITPSNIKQIQHESEQCDIPKDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAVNPHLTEDQRFPQLRLSHKARQKTNVFAPDYIAGVSPFAENDISSRSAILQVRDSMLGAGRRRLNPNASRKKFVKKR
What is the function of this protein?
May play a role in mRNA degradation (By similarity).  Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity).
What are the official names of this protein?
RNA-binding protein NOB1.
What is the protein family that this protein belongs to?
Belongs to the NOB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFKA_STRTD
Sequence: MKRIAVLTSGGDAPGMNAAVRAVVLKAISEGIEVFGINRGYAGMVEGDIFKLDAKRVENILSRGGTFLQSARYPEFAQLEGQLKGIEQLKKYGIEGVVVIGGDGSYHGAMRLTEHGFPAVGLPGTIDNDIVGTDYTIGFDTAVATATEALDKIQDTAFSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEYDINEVVRKVKEGYESGEKSHHIIVLAEGVMGAEEFAAKMKEAGDTSDLRATNLGHVIRGGSPTARDRVLASWMGAHAVDLLKEGIGGVAVGIHNEQLVESPILGTAEEGALFSLTEDGKIIVNNPHKARLDFAELNRSLANLK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_STAA1
Sequence: MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGPDMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKDGNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U512A_DICDI
Sequence: MAIFKSISSISNSTVSIGSTIGSSNHTRSNINGNSIACFDGGLGGSNGGFNCGWGGIGGFNGGCGVGGSNTNIINLDIDIGRRHRRHSYCC
What are the official names of this protein?
UPF0512 protein A.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: NAGS_VANPO
Sequence: MWKHLLSGGLKVEQQNASAKKLILSVLNSTATKREARDYLTKYTRSDDSKQLNHCLLLIRHLNSLRQHEISELTSTVKKLGMLGLRPIFVIPPSRHIAKQAEILDIITTLAGFRPLQLQNSLSQSIDGTYTSILSSQNAILNNHELEVVPILKPYVYREKDASEFLTNDFTKFMQNLCKGNNTHIDKFFILNRIGGIPSNERNENSHVFVNLSQEYDCLKKDLKGQVDLLIERRPRTESLLHKLELHLNEDAINTLENQFKEHLQDLEMMNVVLSNLSSSATGLITTIESAASSSEKKNPLIYNILTDRSLISSSLPRFKKIRHTPPSGSRPAKKFHRMTYLEDYQQLDKSSPPDSALVTTVFKKGIDIKIFDYPKLTQFNSLSLPVEFRVKDSPQTNPLHKIDLSKLKGLIDRSFKRSLNLNHYLHRINGNIASIIVIGDYDGIAILTNEGPNDNPFVYLDKFAISPEMKGSLCISDIIFNLMVKKFPKELLWRSRNDNVVNKWYFQRSVGVLDLSIDLGDGNQTKSNFNLFYYGEPKSTNYGFHNLARLKEYAKHIRDIHPSWDK
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SLMA_ERWT9
Sequence: MVEKKSAKRNRREEILQALAQMLESSDGSQRITTAKLAANVGVSEAALYRHFPSKTKMFDSLIEFIEDSLITRINLILKDEKETMPRLRLITQLILGFGELNPGLTRILTGHALMFEQDRLQGRINQLFERIELQIRQVMRERKMREGEGFATDEALLATQLLAFCEGLLSRFVRSEFRYRPTVDFDARWPLMAAQLI
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: BAMA_KLEP7
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRPGDTVTDDDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFSTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKFSGVQVTGNLAGHSAEIEALTKVEPGELYNGAKVTRMENDIKKLLGRYGYAYPRVQSQPEINDSDKTVKLHVNVDAGNRYYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKDRLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYTELSVTNPYFTVDGVSLGGRVFYNDFDANDADLSDYTNKSYGTDITLGFPVNEYNTLRAGVGYVHNSLSNMQPQVAMWRYLNSMGQYPDNTNDRNSFSANDFTFNYGWTYNKLDRGFFPTEGSRVNLNGKVTIPGSDNEYYKATLDTATYVPIDNDHQWVVLGRTRFGYGDGIGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPASSRHDDDDSYDNECKSTESAPCKSDDAVGGNAMAVASLELITPTPFISDKYANSVRTSVFWDMGTVWDTHWDSSAYAGYPDYSDPSNIRMSAGIAVQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HMUV_CUPMC
Sequence: MLIARNLSCSRGRRQILSGIDLTLPAGEMVGVLGANGAGKSTLLGTLAGELPGDDAAVSLCNRPLTDWPVDELARSRAVLPQSPGLGFDLGVTEVVAMGGYPFPEMGKHTLDTLLDRALALADVAHLATRSYQSLSGGEQQRVQFARALVQVLACRTADSYRALLLDEPISSLDPRHQLQLLGTARNLCHTDALAVLVVLHDVNLAARWCDRLVLLADGRTVASGTPADVLTPPNLATVYGIPATVMESPVHRGVPMVVFG
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.