PharMolix/UniProtQA huggingface dataset:
Protein: AROS_CHICK
Sequence: MSASLIRRGLELLEAPGQGKAPPALQQGRDGTRPAGTARRRKVTAGPGKNKATIKGRVVKSAIEEYHKKKAVNHLKANLLYMTSGRCVADKAVTQQVLTQNRGRKSKDRPAEKKEKKKPEGTVFTEEDFRKFEREYFGIP
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Acts as a chaperone that specifically mediates the integration of RPS19 in state post-A1.  Direct regulator of SIRT1.
What are the official names of this protein?
Active regulator of SIRT1, 40S ribosomal protein S19-binding protein 1, RPS19-binding protein 1, S19BP.
What is the protein family that this protein belongs to?
Belongs to the AROS family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CBIHC_ARCFU
Sequence: MLLLPSRGKLYVVGIGPGKEELMTLKAKRAIEEADYIVGYQTYVDRISHLIEGKKVVTTPMRKELDRVKIALELAKEHVVALISGGDPSIYGILPLVIEYAVEKKVDVEIEAIPGVTAASAASSLLGSAISGDFAVVSLSDLLVPWSVVEKRLLYALSGDFVVAIYNPSSRRRKENFRKAMEIVRRFRGDAWVGVVRNAGREGQQVEIRRVSEVDEVDMNTILIVGNSETKVVDGKMFTPRGYSNKYNIGEKRRAERMGASTKGGMEVARRSEEILRSFYPEEGLRGDIIRRCIATTGDVTIKDVIRFVGDTEEGVRALRDGCRIIADVHMVRAGLRRDAIVAVDFARGDDTRTASGIRNLAEMIEGSLVAIGNSPSAAFALCEVAEKHPPRFIVATPVGFVNAAESKEMVRKLPVPSVTTEGPRGGSGICAAIVNCLIEHADRPD
What is the function of this protein?
Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate.
What are the official names of this protein?
Cobalamin biosynthesis protein CbiHC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CobH family.
Protein: LPXK_PSEFS
Sequence: MAMSDRLLKAWYEGHPALALLRPLESLYRRVVQRKRTRFLAGEGEIYQSPVPVVVVGNITVGGTGKTPLILWLIEHCRRSGLRVGVVSRGYGAKPPQLPWRVEASHSADLAGDEPLLIVQRCGVPLMIDPDRSRAVKALLASETLDLILSDDGLQHYRLARDLELVLIDAARGLGNRRCLPAGPLREPVERLQSVDALLYNGAASDREDGFAFRLQPAALVNLQTGERQPVDHFAPGQQVHAVAGIGNPQRFFNTLETLHWQPISHAFADHAPYSAEVLNFTPSLPLVMTEKDAVKCRAFAQPDWWYLAVDALPSPAFVAWFDTQLMRLLPARLLP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RUVC_CORGL
Sequence: MNHEGLRVMGIDPGLTRCGLSVVQAGRGRTVYPVSVGVVRTPPDAELAERLLRLSKAVGEWMDEYTPDVIAIERVFERGNVSTVMNTAHAVGVLILAAAERGLPVHMYTPSEVKKAISGNGRADKKQMTVMITRILGLGEPPKPADAADALSLAVCHCWRAPMLMRAQSQYSEQELEKRRRVQQGKLGKAKSTYNAEQAQSHASDPAKAAHPSQFQRTDTN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SYR_FUSNN
Sequence: MKITSRELTDIFQKHVENLFPNKELKPVEITVATNENFGDYQCNFAMINSKIIGDNPRKIAEEVKNNFPYGDVIEKLEVAGPGFINIFLSDKYISNSIKKIGEDYDFSFLNRKGKVIIDFSSPNIAKRMHIGHLRSTIIGESISRIYRFLGYDVVADNHIGDWGTQFGKLIVGYRNWLDKKAYKKNAIEELERVYVKFSDEAEKDPSLEDLARAELKKVQDGEEENTKLWKEFITESLKEYNKLYKRLDVHFDTYYGESFYNDMMADVVKELVDKKIAVDDDGAKVVFFDEKDNLFPCIVQKKDGAYLYSTSDIATVKFRKNTYDVNRMIYLTDARQQDHFKQFFKITDMLGWNIEKYHIWFGIIRFADGILSTRKGNVIKLEELLDEAHSRAYDVVNEKNPNLSEGEKQNIAEVVGVSSVKYADLSQNKQSDIIFEWDKMLSFEGNTAPYLLYTYARIQSILRKVAELNIGLNENIEIKTENKIEKSLATYLLAFPISVLKAGETFKPNLIADYLYELSKKLNSFYNNCPILNQDIETLKSRALLIKKTGEVLKEGLELLGIPILNKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_PANAM
Sequence: MTEDTSMQSTLNATLPETDMPLAEKEAAVEKQEYRNAMARLGSAVNIITTDGPGGRAGFTASAVCSVTDTPPTLLVCLNRSASVHPAFIQNQVLCVNTLADSHESLSNLFGGKTPMEQRFDAAEWTDLATGSPILTNALVSFDCKVTQITRVGTHDIMFCEVVALRCNDDCHGLAYFDRRYHPLMRQIAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: NAGB_SHIB3
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ENGB_LEVBA
Sequence: MEVNHVELVMSAVDPAQYPTTGYPEIALVGRSNVGKSSLTNVLINRNSYARTSSQPGKTQTLNFYNVEDQLYFVDVPGYGYAKVSKTEREKWGQMIETYLTQRDQLRGVISLVDARHAPTEDDIQMYRWLAYYELPTLIVATKSDKIARGKWNQAVSQIKKSLELPNTDNIVMFSAPKKMGKDAVWNWIEAQAFGGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ABRAL_MOUSE
Sequence: MNVEHEVNLLVEEIHRLGSKNADGKLSVKFGVLFQDDRCANLFEALVGTLKAAKRRKIVTYAGELLLQGVHDDVDIVLLQD
What are the official names of this protein?
Costars family protein ABRACL, ABRA C-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the costars family.
Protein: LOLB_SHEB8
Sequence: MNNLKRLTKTIFSCFTLSALLLLAGCETLPPMTDLSPITVTDARQATAWELQGKLAIKTPDDKLSANIYWRHSKDRDELTLTTMLGTTVLTLNSTPNSAHLHIDGKDFRDDNAQRLLERVSGWSIPLADLPLWITGQVGPNDQVIARDSQGKPKQLTNTQTPPPWQVAFLSWQSQSGASVPHQLKLERGDLQLKLQLNQWQALGKPAILVGEQP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RUVA_RHOPS
Sequence: MIGKLKGLIDSYGEDYVILDVHGVGYQVHCSSRTLQALPSPGEAATLSIETYVREDQIKLFGFRTDHEREWFRLLQTVQSVGAKVALAVLSTLPPNDLANAIALRDKAAVARTPGVGPKVAERIVSELKDKVPALSNVDPAVVQLSGALDDNRAPRPVTDAISALVNLGYGQPQAAAAIAAAARAAGDDAATAQLIKLGLKELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CEMA_NASOF
Sequence: MAKKKAFIPFFYFTSIVFLPWLISLCCNKSLKTWITNWWNTRQCETFLNDIQEKSVLEKFIQLEDLFQLDEMIKEYTETDLQQFRLGIHKETIQFIKIHNEYRIHTILHFSTNLISFVILSGYSFWGKEKLFILNSWVQEFLYNLSDTIKAFSILLLTDLCIGFHSPHGWELMIGYIYKDFGFAHYEQILSGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHAIND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: DNAK_LEGPL
Sequence: MAKIIGIDLGTTNSCVAVMEGDKPKVIENSEGHRTTPSIVAFTDDNEILVGQSAKRQSVTNPEKTLFAIKRLIGRRFDDPIVQKDIKMVPYKIMKADNGDAWVRVKDQDKAPPQISAEVLRKMKKTAEDYLGEEVKEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGMDKKRGDSVIAVYDLGGGTFDISIIEIAEVDGEHQFEVLATNGDTFLGGEDFDLALIEYLASEFKKDTGIDLHNDPLALQRLKEAAEKAKIELSSAQQTDVNLPYITADASGPKHLNIKLTRAKLESLVEKLVERTIEPCKTALKDAGLTVSQINEVILVGGQTRMPLVQKTVEEFFGKEPRKDVNPDEAVAVGAAIQAAVLSGEVKDILLLDVTPLSLGIETMGGVMTKLIEKNTTIPTKATQVFSTADDNQTAVTVHVLQGEREQASANKSLGRFDLRDIPPAPRGVPQIEVTFDIDANGILNVSAKDKATGKAQSIVIKASSGLSEEEVAAMVKDAQSHAEEDKKFKEMAELRNQADSLIHSCEKSMKDLADELSEDEKKGIETAISELKEAVQGTDKARIEDKLKVLTDASAKMAERIYAKKSSEGQTAQGQTQSQESTKPAEEGVVDAEFEEVKEEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YQGF_ZYMMO
Sequence: MDEKREENILKKQEELRLFQEALPRKGRLAGLDVGTKTIGLALCDSQWIIASPAETIRRKKFTLDLELLRQFVEKQQVKGLVIGLPLNLDGSDSPRTQSVRAFAKNVAPLSLPVLMWDERWSTKAVTRTLLEADASRARRSEVVDKMAAAYILQGAIDSFAMF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_BACHK
Sequence: MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDYIVLGADTIVTYESRILGKPSNEAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC11_BLAGS
Sequence: MLSSLSPYMANPRQTFTQVLNFALVLSTAFMLWKGLSVYTNSASPIVVVLSGSMEPAFQRGDLLFLWNRSPRVDVGEIVVYNVRGKDIPIVHRVMRTFPDVPGKDKTKKGGKQDVEASPSSLESQKLLTKGDNNLSDDTELYARGQDYLDRKEDIVGSVRGYIPAVGYVTIMLSEHPWLKSVLLGFMGLMVILQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RL18A_METS5
Sequence: MTEVKTFMVKGAALFNESEFPVRQSFTKYVRALNEEQAKEKVYMDLGSKNKIKRRNITFLEIKEVDPSTVKEKRIKELSKIDKIIL
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: CENPX_ARATH
Sequence: MDANNTFDSDLIHAIFKHIWARRFRERERSDAIDATEAEVALGTTKKNRLASANANALKLSCELLKSFVSEAVQRAAIIAEAEGMEKIEATHLERILPQLLLDF
What is the function of this protein?
Acts in the same pathway as FANCM to restrain class II meiotic crossing over (CO), and acts with FANCM during meiosis to repair interstrand cross-links (ICLs).
What are the official names of this protein?
Protein MHF2 homolog, AtMHF2.
What is the protein family that this protein belongs to?
Belongs to the CENP-X/MHF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGT_ECO81
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHNN_DESBD
Sequence: MSKLIYIMGPSGSGKDSLMAEARLRLAAEAPVVFAHRYITRPADAGGENHVALSRAEFQLRLSRGLFALSWESHGFAYGIGREIDIWMESGLSVVVNGSRGALSAALQAYPELLPVLIDVPEHILRERLGARGREDAGEIEARLVRARMAVVEAPELVRFDNSGPLAERGQALAGLILETTISGRKS
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: AB11C_ARATH
Sequence: MGFEALNWYCKPIAEGFWEKTPDGAFGAYTPCAIDSLVMIVSNSVLLGLCFYRIWITLYNAKAQIYVLRKMYYHCVLWILACCCVVEPVLRLVMGISLFDMGDETDLPPFEVASLMVEAFAWFAMLVLIGLETKQYVKEFRWYVRFGVVYVLVADAVLLDLVLPLKNSINRTALYLCISSRCCQALFGILLLVYIPELDLYPDYHILNNESLDNVEYDALPGGVNICPERYASIFSGIYFSWMTPLMQLGYRKPITERDVWQLDQWDQTETLIKRFQRCWTEESRRPKPWLLRALNNSLGRRFWLGGIFKVGHDLSQFVGPVILSHILQSMIEGDPAWVGYVYAFLIFFGVTFGVLCQSQYFQHVGRVGFRLRSTLVAAIFHKSLRLTNKARKNFASGKVTNMITTDANALQLIAEQLHGLWSAPFRIIVSMVLLYQQLGVASIFGSLILFLLIPFQTLIVRKMRKLTKEGLQWTDKRVGIIYEILASMDIVKCYAWEKSFESRIQGIRNEELSWFRKAQLLSAFNSFILNSTPVVVTLVSFGVYVLLGGDLTPARAFTSLSLFAVLRSPLSTLPNLISQAVNANVSLQRIEELLLSEERILAQNPPLQPGAPAISIKNGYFSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVDIRGSVAYVPQVSWIFNATLRENILFGSDFESERYWRAIDVTALQHDLDLFPGRDRTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPFSALDAHVAHQVFDSCVKHELKGKTRVLVTNQLHFLPLMDRIILVSEGMIKEEGNFAELSKSGTLFKKLMENAGKMDATQEVNTNDENISKLGPTVTIDVSERSLGSIQQGKWGRSMLVKQEERETGIISWDVVMRYNKAVGGLWVVMILLVCYLTTEVLRVLSSTWLSIWTDQSTPKSYSPGFYIVVYALLGFGQVAVTFTNSFWLISSSLHAAKRLHDAMLNSILRAPMLFFETNPTGRVINRFSKDIGDIDRNVANLMNMFMNQLWQLLSTFALIGIVSTISLWAIMPLLILFYATYIYYQSTSREVRRLDSVTRSPIYALFGEALNGLSSIRAYKAYDRMAKINGKSMDNNIRFTLASTSSNRWLTIRSESLGGVMIWLTATFAVLRYGNAENQAVFASTMGLLLSYTLNITTLLSGVLRQASKAENSLNSVERVGNYIDLPSEATAIIENNRPVSGWPSRGSIQFEDVHLRYRPGLPPVLHGLSFFVYPSEKVGVVGRTGAGKSSMLNALYRIVELEKGRILIDDYDVAKFGLTDLRRVLSIIPQSPVLFSGTVRFNIDPFSEHNDADLWEALERAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILFLDEATASVDVRTDSLIQRTIREEFKSCTMLIIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFFKMVHSTGPENGQYLSNLVFERRGNGMSQGG
What is the function of this protein?
Pump for glutathione S-conjugates.
What are the official names of this protein?
ABC transporter C family member 11, ABC transporter ABCC.11, AtABCC11, ATP-energized glutathione S-conjugate pump 12, Glutathione S-conjugate-transporting ATPase 12, Multidrug resistance-associated protein 12.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: WDR89_DICDI
Sequence: MDQLISQLNFKSHNSIIHSVDSIGDDTCYVLDLSVTPNLLAAAGSNYLIKIYDRSNNTILNVLSGHKDAINETKFIENTNTLLSCSSDKTVKIWDTKTGQCSQTINQQGEIFSIDLNGDILAMGVGSMVVLYNLSTKKMIRKFDCSHTEDVTRVRFHPIDKNKLVSCSVDGLICMYDLEQADDDDAIVHVINAEDSIGNIGFFGSAYQYLYTLSHTERLATWDLTTGLKIKHYGADLRSTLSDRYKFEINYFISCIYDNASNQLILFGGDFNGTGHVFLVTPDEVIQISKLENVHTDVIRNVFWDKFKSELITSSEDSKIGFWTNNPSITNILKINNDTSSNKMKDDKLKSKKTSPYNK
What are the official names of this protein?
WD repeat-containing protein 89 homolog.
Protein: SIA_ARTBC
Sequence: MGIKQWLLSLVVVAISATATQARVDDPAGKAAQYHKEYALFRSANMPSPDKLASGVGFHSFRIPAVVRTNTGRILAFAEGRRHNNRDYGDINLVYKRTKSPTNNGENPTDWESLREVVGTGPHTWGNPTPVVDGNTIYLFLSMNDGAYSQNGGNTLPDGTKTKTIDSTWVGRRHLYLTTSTDDGDTWTKPVDMTKTLTPDGQAWDAVGPGNGIKLSTGELVIPAQGRNIIGHGPSGNRTWSMQVLKGAGSEGTICQTPDGKLMRNDRPGPMGHRSVARGTLAGFGPFATDNGLPDPACQGSILSYNSDEPARTIFMNSASTDRRTAMRVRISYDKDAAKFNFGRELKDAPLGNVGNEGGYSSMTKTSDYKIGALVESDWYEDKGGEKSHRCIIWRRFNLSWIINGPNN
What is the function of this protein?
Sialidase is able to release sialic acid from a wide variety of natural substrates.
What are the official names of this protein?
Exo-alpha-sialidase ARB_03431, Alpha-neuraminidase ARB_03431, N-acylneuraminate glycohydrolase ARB_03431.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB1_CRYNJ
Sequence: MSMAASSSTATVQPSGIITQPPPPSTLREQRIATHSHIKGLGLADDGTAMSSSQGFIGQILAREALGLHLSLLKGGKYSGRPLLLVGPPGTGKTALALALSQELGSKVPFCAMVGSEVYSGEVKKTEVLGSCFRRAIGLRIKETKEVYEGEVTELTPSEAENPLSGYGKTISHVIVGLKTVKGTKQLRLDPSVYESIQKERVVVGDVIYIEANTGAVKRVGRSDAYASEYDLEAEEYVPLPKGDVHKRKELVQDVTLHDLDMANARPQGGQDIMSVMGQLVKGGRTEVTDKLRREINKVVDRYIEQGVAELVPGVLFIDEVHMLDMECFTYLNRALESPMSPYVVLASNRGISTIRGTEYDGVAGSASEGIRAPHGLPVDLLDRCMIVKTQLYTRDEIRRIVEMRCKVEGIAISSEAVDKLADEGERSSLRYALQLLTPAGIVSKNKGKGEVGVADVEELGELFLDAKRSAGVLRSTEDFEKRY
What is the function of this protein?
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.  The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair.  Also involved in pre-rRNA processing (By similarity).
What are the official names of this protein?
RuvB-like helicase 1.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1126_CLOBA
Sequence: MSKNIEHTMQFDLNKTKEALTKAILTEVYDSLQQKGYNPINQLVGYLISGDPTYITNYNGARALVRKLERDEILEEVIKSYLEIK
What are the official names of this protein?
UPF0297 protein CLH_1126.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: LPXA_CHLCV
Sequence: MTNIHPTAIIEPGAKIGKNVVIEPYVVIKSTVTLCDDVVVKSYAYIDGHTTIGKGTTIWPSAMIGNKPQDLKYQGEKTYVTIGENCEIREFAIITSSTFEGTTVSIGNNCLIMPWAHVAHNCTIGNYVILSNHAQLAGHVVVEDYAIIGGMVGVHQFVRIGAHAMVGALSGIRRDVPPYTIGTGNPYQLGGINKVGLQRRQVPFETRLALIKVFKKVYRSEDSFSESLLEAQEEYGHIPEVQNFIHFCQNPSKRGIERGADKDALQDESVEKEGALVES
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_ASPEL
Sequence: KASVGFKAGVKDYRLTYYTPDYETKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEAVVGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRVTFARELGAPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRRRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTIGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SSRP_PSE14
Sequence: MAKLKKNPTGTIAQNKKARHDYFIEHKFEAGLVLAGWEVKSLRATKVQLVDSYVLLKDGEAWLMGCHITPLKTASTHVIADPTRTRKLLLNKRELEKLTSSVQQKGYACVALSVYWKEHLIKCEIALGKGKKEYDKRHTERERDSDRELQRAVRSKGKDD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.