PharMolix/UniProtQA huggingface dataset:
Protein: SYS_DESHD
Sequence: MLDLKFVRTNPEVVKEALKKRNSNVSLDAFLEQEEERRKLLFEVESLKAQRNTVSEEVGRRKKHGEDAEQLILEMREVGQKVKNLEDKLGEIEQSMEAVLYEIPNIPHESVPVGADEEANVEVRTWGTPRSFDFEPLAHYEIGEKLDILDFARAGKVTGARFTFYKGLGAKLERALISFMLDRHSAKGYVEVLPPYMVHRNSMIGTGQLPKFEEDAFKVAGTDYFLIPTAEVPVTNMYREEILEAEQLPIHHCAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFAFPENSYEELESLTRDAESILQELELPYRVMALSTGDLGFTSAKTYDLEVWLPSFNTYREISSCSNFEDFQARRANIRFRRAPKAKPEFLHTLNGSGLAIGRTVSAILENYQEADGRVRVPKALQPYMGVEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMAP1_HUMAN
Sequence: MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTAEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKNAIAITNISSSDAPLQPLVSSPSLQAAVDKNKLEKEKEKKKEEKKREKEPEKPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLSQMNQQMAGMSISSATPTAGFGQPSSTTAGWSGSSSGQTLSTQLWK
What is the function of this protein?
GTPase activating protein that acts on ARF6.  Plays a role in clathrin-dependent endocytosis.  May play a role in erythropoiesis (By similarity).
What are the official names of this protein?
Stromal membrane-associated protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TMX4_MOUSE
Sequence: MTGGFCVPVLLAAWLAAAAAEGLEQAALPAEESRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWETFAKNGETLQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLILVVISECFCVPLPRASSERCEQEQSTGEAQGAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDIGDEDEGEEDEEEDNLAGIMAEERSDTNERAVVKEGSVSPKEDGAHPADTQDVVEDALRQRKSQNANKGS
What are the official names of this protein?
Thioredoxin-related transmembrane protein 4, Thioredoxin domain-containing protein 13.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass type I membrane protein.
Protein: RL6_RICAH
Sequence: MSRVGKLPITIPEGVTVGLNDLEVKISGPKGELSKIFKGNIAISLAENKLLVKPLAANKSARAMWGTARSIISNMVIGVKEGFKLKLEINGVGYRAMVKGKYLNLMLAKSHNTKIEIPSHIKIDVPKQNIIILEGTDKEKLGQFASIIIKQRPPEPYKGKGIKFDNQFIPRKEGKKN
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL20_CARRP
Sequence: MTRSKPNKNTKKYLKHNKGFYGRKKNCLKLAKQYYIKSLFKKYIDKKNKKRLILKKKIALINFFSRIYFGLSYSKFVYILKINNCKLNKNIILFLLLKTIV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LMT1_LOCMI
Sequence: GAVPAAQFSPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Locustamyotropin-1, Lom-MT-1.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: M2_I88A7
Sequence: MSLLTEVETPIRNEWGCKCNDSSDPLVAAASIIGILHLILWILDRLFLKCIYRRFKYGLKRGPSTEGVPESMREEYRQKQQSAVDVDDGHFVNIVLE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: IF2_BRASO
Sequence: MADQNTPGDKKLGVPSKTLTLKPRVETGTVRQSFPHGRSKQVVVEKRGTKRRVGDGAPDAPHAPEPTVAKAPPPPPPSNRPSGPRPSGGQQRGGSGVVLRTLTEDERSARASALADARVRDLEERRQAEEEARRRAEREAAERAEREAAEARRKAEEERHRHEEEAKRKAELEAKKRFGEGEAPRPAAAAPQPTVSAPARPAQAPGRPQGAPGSRPQQIGGPSSRPGGSQPGGARPAGPRPAGGGPLGRAPAAVAAGPDEDEGPRQIRRGPGGAARPAPPPKTTHKPGPQKQRGRLTVVTALNADDVRERSIASFRRRTQRLKGHAANEQKEKLVREVTIPEAITIQELANRMSERAVDVIRLLMRQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVTAPDSGKKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAKAAKVPMIVAINKIDKPDARPERVRTELLQHEVQVESLGGDVVDVEVSAKNKTNLDRLLEMIALQADILDLKTNSDRPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETLQEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQVTSYRAHQKRENAAASISGMRGSLEQMMSQLKTAGRKEFPLVIKADVQGSLEAILGSLEKLGTEEVAARILHAGVGGISESDVTLAEGFNAAIIGFSVRANKEAAALAKRNGIEIRYYNIIYDLVDDVKKAMSGLLAPTLRETMLGNAQILEVFNISKVGKVAGCRVTDGTVERGANVRLIRDNVVVHEGKLSTLKRFKDEVKDVQAGQECGMAFENYGDMRVGDVIECYRVETIQRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRAM_I76A6
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECDSPANNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTKILFIEEGKIVHTSPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINVKDYSIDSSYVCSGLVGDTPRNNDRSSSSYCRNPNNEKGTHGVKGWAFDDGNDVWMGRTISEDSRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: MUR3_ARATH
Sequence: MFPRVSMRRRSAEVSPTEPMEKGNGKNQTNRICLLVALSLFFWALLLYFHFVVLGTSNIDKQLQLQPSYAQSQPSSVSLRVDKFPIEPHAAPSKPPPKEPLVTIDKPILPPAPVANSSSTFKPPRIVESGKKQEFSFIRALKTVDNKSDPCGGKYIYVHNLPSKFNEDMLRDCKKLSLWTNMCKFTTNAGLGPPLENVEGVFSDEGWYATNQFAVDVIFSNRMKQYKCLTNDSSLAAAIFVPFYAGFDIARYLWGYNISRRDAASLELVDWLMKRPEWDIMRGKDHFLVAGRITWDFRRLSEEETDWGNKLLFLPAAKNMSMLVVESSPWNANDFGIPYPTYFHPAKDSEVFEWQDRMRNLERKWLFSFAGAPRPDNPKSIRGQIIDQCRNSNVGKLLECDFGESKCHAPSSIMQMFQSSLFCLQPQGDSYTRRSAFDSMLAGCIPVFFHPGSAYTQYTWHLPKNYTTYSVFIPEDDVRKRNISIEERLLQIPAKQVKIMRENVINLIPRLIYADPRSELETQKDAFDVSVQAVIDKVTRLRKNMIEGRTEYDYFVEENSWKYALLEEGQREAGGHVWDPFFSKPKPGEDGSSDGNGGTTISADAAKNSWKSEQRDKTQ
What is the function of this protein?
Involved in the attachment of the Gal residue on the third xylosyl unit within the XXXG core structure of xyloglucan, the principal glycan that interlaces the cellulose microfibrils in plant cell wall (PubMed:12837954).  Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066).  Interacts with actin and is required for the proper endomembrane organization and for the cell elongation.  Not involved in the trafficking from the endoplasmic reticulum to the vacuoles (PubMed:15863516).  Involved in salt stress tolerance.  Participates in the control of the expression of genes encoding for proteins involved in reactive oxygen species (ROS) detoxification under salt stress.  May contribute to the maintenance of the proper organization of actin microfilaments during salt stress-induced ROS production (PubMed:23571490).
What are the official names of this protein?
Xyloglucan galactosyltransferase MUR3, Protein KATAMARI, Protein MURUS 3, AtMUR3, Protein SHORT ROOT IN SALT MEDIUM 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: AP2B_SCHPO
Sequence: MSSSSSHFSSTAADLLAVFSSDNKDKSANKRISALKKAIAGISYGYDMSSLFPSVISSMESNNLELKKLCYLYLKIYASVKPTEAKRAVKLILNDIYSSNPMIRSLALRTLTSVNIKNFWVAAMDPIVRLLDDTDPYVRKTAAIGIAKLYSYDKKMVESSGLIDHLKEMLSDESSVVVANSLAALMNIVNSSTGFKLTFSREISNKLVKSLTDCSEWLQVAILDALIFYVPQKPGEAESFAERISPWLQHGNAAVCMGAVKVILYLTNYMKDDNRVKEYFMKTQPPLVTLLARKSSATQYVILRNIQIILEQCPEMFANDIHFFYCNFDDPIYVKLEKLDILTKIADIHNLDQILPEFVEYASEIDVELVRKSVKCIGYLAIKIEERKNDCIDSLIELMNTKVTYVIQEAVIVIRDILRKYPGSYKSLVPILYENLDSLDEPDAKSAVIWILGQYAEEIEDSITLLNDYLKGFFDEPLEIQLTLLTAVIKVFLKKPTAAADMVTNVLQWCTDEVNDPDLRDRGIIYSRMLSANPELAKKVILANMPPVNVGTGMYDPDTTEQLMLNISTLSSIYHKPPNRFVKGAQVAYCEPSPVLRLRTRDSNPSNTDSRESNHKKYNHFHQKSQTRRVMEQYDRNSWNPSPFSDESNSNTFSGKFDSADQENLGMPMTPETHLMD
What is the function of this protein?
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  Beta adaptin is a subunit of the plasma membrane adaptor (By similarity).
What are the official names of this protein?
AP-2 complex subunit beta, Beta-2-adaptin, Beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Clathrin assembly protein large beta chain.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.
Protein: SYP_ACTPJ
Sequence: MRTSQYLFSTLKETPNDAQVVSHQLMLRAGMIRPMASGLYNWLPTGIKVLKKVENIIREEMNKGGAIEVLMPVVQPAELWQESGRWNDYGAELLRFVDRGSRDFVLGPTHEEVITDLVRREVSSYKQLPLNLYQTQTKFRDEVRPRFGVMRSREFVMKDAYSFHVDKASLQETYDVMYQVYSNIFTRLGLDFRAVQADTGSIGGSASHEFQVLASSGEDDVVFSTESDFAANIELAEAVAVGERQAPTAEMQLVDTPNAKTINELVEQFNLPIEKTVKTLIVKGATEEQSLVALVLRGDHELNEIKAQKHPLVADPLEFADEAEIKAKIGAGVGSLGVINLNVPAIIDRSVAVMSDFGCGANIDGKHYFNVNWERDVAMPEVADLRNVVEGDPSPDGKGVLQIKRGIEVGHIFQLGTKYSEAMKATVQGEDGKPLVMTMGCYGIGVTRVVAAAIEQHHDERGIIWPSDEIAPFTVAIVPMNMHKSESVQQFSEELYRTLKAQGVDVIFDDRKERPGVMFADMELIGVPHMVVIGEKNLANGEIEYKNRRTGEKQMIAKDQLLAFLKENVKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMSB_MYCTO
Sequence: MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDFSAVIHTLRARADA
What are the official names of this protein?
Probable 3-hydroxyisobutyrate dehydrogenase, HIBADH.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family.
Protein: PRCA1_HUMAN
Sequence: MWVRTTLTIERWTKEKTEPKARSWDEALSDVNRLPSWERGHLLAGVASSTDVSTFSEGGDCKEPDKCCWRHKQCTGHIIYPFASDCVRHSLHLHSVNHCNCNSRLKDSSEDSSSSRGAGPTCSHVIESPCFELTPEEEHVERFRYGWCKSYRPVSVAVIHHPLYHECGADDLNEEEEEEEEESKPPIPTQVGPATASPDLGTSMATGTPDSTAPITIWRSESPTGKGQGSKVIKKVKKKKEKEKDKEEMDEKAKLKKKAKKGQLTKKKSPVKLEPSPPDVSRSLSARQLARMSESSPESREELESEDSYNGRGQGELSSEDIVESSSPRKRENTVQAKKTGAKPSQARKVNKRKSPPGSNPNLS
What are the official names of this protein?
Protein PROCA1, Protein interacting with cyclin A1.
What is the protein family that this protein belongs to?
Belongs to the PROCA1 family.
Protein: VPS10_SORMK
Sequence: MRVRGALQAAALLASALWASPLLAKDHPDFKTTKLDTQPNNLNYFQGSDTILFHDPHKANLWRSDDAGATWSVVKDIPDGKVARLYMHDFDPKRAFAITDGRKHYRTTDQGKTWKKFEINAEWDTERYDILHFHATDPDRIIFNGLNCLGFLCEEVSLYTIDGFDTPAKPLRPDTLGCWWAKSNALFTTGDSDLDKDRILCIIMGVDSIFTEDRRLVISDDFFKADKEGNIQEFEPNLAGDKPVRGVVNVAAVKRYFMVATTSANTDEMALFISTDTKKWQRAMFPNAHDDHDHKIVQEAYTVLESTNYSIQLNVMTGSKSQPMGIMFTSNYDGTYFTENLEYTNLNMYGHVDFEKIAGIQGIFLVNKVDNGKDVDEKPSTKKKLVSEITFDDGRTFEKVTADGKRIHLHSVTELNNVGRVFSSPAPGLVMANGNTGDYLEDYWDANLYVSDDAGKTWKKALKGPHKYEFGDQGSILVAVRDSKEEDVSEISYSLDHGENWVEEKLPDDLKIQPWILTTTPDSTTLQFVLIGKAKGAWQVIHIDFEALHEATCKDSDMEEWHARVDKDGESTCIMGHTQTFPRRKKDAKCFLKKEFKLAEVETKDCDCTDQDYECDYSFERNDKGNCVSKGPIPIPEGACKDGDKNGKFMGTSGYRKIPGNTCKDTKDTKDKYKDVERSCGDGIGAPPEEATGELQQVDTKGKFGHWTQWEKHYLERGESSSDSSETIIMRGKNRTVDDSGPKAGPIWRTTDHGKTWEKIDFFKDEEVISIVPHPTVKDWVFFLTEGKKLIYTPDRGKRFRTFDVPQPADLEAAANGIFPLIFHPDKPNWLIWLGKKCESKNDCYRVAYGTKDGERWETLARDVYRCEFTGAEAYGRKYANRALEQILCLKHEKEGASDSALQLVSSNDWFNKDEKVRLKDAKEFATMAEFIVVATEDTEKKTLRAHASLDGGLYSEAKFPFGFEVPHQHAYTVLDSSTHAVNLFVATKMEGDKSLGTILKSNSNGTSYVVSVKNVNCDQYFYVDFEKMVGLEGVALVNVVANPDAKSSAPQKLQTKITHNDGAQWAYLPTPSKDEFGRFPCSSSGTEKCALHIQGYTQRRDRGKTYSSEGAVGVMFGWGNVGDSLGPLKDADTFMTTDAGITWKRVKKGRWNWALGDQGSIIVMVPIRGQKTDTLEYSLDQGATWKKHTFSKEKVDIWDLTTTRSGNSQNFLIWGENSDGLFTTKIDFTKFTDHVCKYDPENLGKSDYQIFSPKHPLQPDGCLFGHVSQYLRKKPGLKCFNDFRLDPLYSKQNCTCTRSDFECDFNYELDNHGQCALVKGLKPQDPKLWCKEHPDEIEYYEPTGYRRIPLTTCQGGADFEKQAAVHPCPGHEDDFERKHRISGIAIFFAVVLPVAAASAIGWWVYRNWDGKFGQIRLGEQGASTMEFFDADRPWVKYPVIALSAVVALAGAMPLVLAAIWRTAKNTAQRFGVGGGGRGGWSRLDGGGASRTFRTRDSFARGRGDYTIVDEDEGELLGEESDEEV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: Y1356_STRPQ
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYGIHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYITIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein SPs0505.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: GPDA_NEIMA
Sequence: MKITVIGAGSWGTALALHFSQHGNRVSLWTRNADQVRQMQEARENKRGLPGFSFPETLEVCADLADALKDSGLVLIVTSVAGLRSSAELLKQYGAGHLPVLAACKGFEQDTGLLTFQVLKEVLPDNKKIGVLSGPSFAQELAKQLPCAVVLASENQEWVEELVPQLNTSVMRLYGSTDVIGVAVGGAVKNVMAIATGLSDGLEYGLNARAALVTRGLAEITRLASAMGAQPKTMMGLAGIGDLILTCTGALSRNRRVGLGLAEGKELHQVLVEIGHVSEGVSTIEEVFNTACKYQIDMPITQTLLQLIRKEMTPQQVVERLMERSARFE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_BRUME
Sequence: MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PA2A1_ECHCA
Sequence: MKTLWIVAVWLIAVEGNLYQFGRMIWNRTGKLPILSYGSYGCYCGWGGQGPPKDATDRCCLVHDCCYTRVGDCSPKMTLYSYRFENGDIICDNKDPCKRAVCECDREAAICLGENVNTYDKKYKSYEDCTEEVQEC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits human platelet aggregation induced by ADP, collagen and epinephrin (possibly by binding the platelet receptor alpha-IIb/beta-III) and induces mild edema in the foot pads of mice.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 EC-I, EC-I-PLA2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLP2_YEAST
Sequence: MQNEPMFQVQVDESEDSEWNDILRAKGVIPERAPSPTAKLEEALEEAIAKQHENRLEDKDLSDLEELEDDEDEDFLEAYKIKRLNEIRKLQERSKFGEVFHINKPEYNKEVTLASQGKKYEGAQTNDNGEEDDGGVYVFVHLSLQSKLQSRILSHLFQSAACKFREIKFVEIPANRAIENYPESNCPTLIVYYRGEVIKNMITLLELGGNNSKMEDFEDFMVKVGAVAEGDNRLIMNRDDEESREERKLHYGEKKSIRSGIRGKFNVGIGGNDDGNINDDDDGFFD
What is the function of this protein?
Essential for cell growth (PubMed:10749875).  Inhibits early G-protein signaling events following pheromone stimulation (PubMed:10749875).  Inhibits the folding activity of the chaperonin-containing T-complex (CCT) CCT2 which leads to inhibition of cytoskeletal actin folding (PubMed:17429077).  Plays a role in cell cycle progression in G1/S phase (PubMed:17429077).
What are the official names of this protein?
Phosducin-like protein 2, Viral IAP-associated factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1591_MYCTU
Sequence: MLGLSATGVLVGGLWAWIAPPIHAVVAITRAGERVHEYLGSESQNFFIAPFMLLGLLSVLAVVASALMWQWREHRGPQMVAGLSIGLTTAAAIAAGVGALVVRLRYGALDFDTVPLSRGDHALTYVTQAPPVFFARRPLQIALTLMWPAGIASLVYALLAAGTARDDLGGYPAVDPSSNARTEALETPQAPVS
What are the official names of this protein?
Uncharacterized protein Rv1591.
What is the protein family that this protein belongs to?
To M.leprae ML1222.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_BRUA1
Sequence: MPKMKTKSAAKKRFKITGTGKVKAAAAGKRHGMIKRSNKFIRDARGTMVLADADAKIVKQFLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MDH_MAGMM
Sequence: MADPIRVAVTGAAGQIAYSLLVRLASGQLFGKDRKVELKLLEIPQAMGPLEGVMMELQDCAFPTLAKVEAFDNPEQAFDGINWCLMVGSRPRGPGMERSDLIKINGPIFVNQGKALNRAAQDVRAVVVGNPCNTNCMIAAHNSDVPHERFSAMMRLDQNRAKYLLASKAGAQVIDVTNVVIWGNHSNNQVPDFEFAKIGGKPVPEVIADAAWLENAFMPTVQNRGAAVIKARGASSAASAANAALDHVRSLITPTPAGDTFCAAVMANGAYGVDAGLIAGMPLTSTGHGDWSIVEGVPMSPFIKGKFDAVLDELRREREMVKDLLPG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: ARGB_BRUSU
Sequence: MTTLENPEMQAQLLSAALPYMQRYENKHVVVKYGGHAMGNPELGKAFARDVALLKQSGVNPIVVHGGGPQIQAMLTKLGIESRFEGGLRVTDEKTVEVVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAQKAHKTVIDPDSNIEKVLDLGFVGEPAEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALAATRLLFLTDVPGVLDKDKKLIKELSVADAQALIRDGTISGGMIPKVETCIDAIRRGVEGVVILNGKTPHSVLLELFTEHGAGTLIVP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.