PharMolix/UniProtQA huggingface dataset:
Protein: VPS74_SCHPO
Sequence: MSGGLSRRRVAAASSDEERPEMRSVSHSKSHLEGYDDDHKIAFDPKDLEQGAEREKQPRLTLMEEVLLLGLKDKQGYLSFWNDSISYSLRGCILMELAFRGKLRMQKDVNRKRFPLADRVVELVDEKLTGEVLLDEAIKMIHTSELMSVTSWIDLMSGETWNVMKIGYQLRQVRERLAKGLVDKGILRNEKKNFLLFDMPTHPIADTSIKDSIKKRVVSVLTSRVIEIDNSPSFPEYLSFRCLRTVALACSSYAANVLENALDNLNYEDREKAFSRVDELLCDFSQWPFDLHASSSVGANLPELISEELSSVKEEQLLFIEVVAAVLQVFTHLDSLL
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi.  Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus.  May also bind to the coatomer to regulate Golgi membrane trafficking.  May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.  Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains.  Involved in vacuolar protein sorting (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 74.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
Protein: SYM_PYRAB
Sequence: MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEDVVFICGTDEHGTPISFRALKEGRSPREIVDEFHEQIKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQAYCEHDKMFLPDRFVIGTCPYCGAEDQKGDQCEVCGRPLTPEILINPRCAICGRPISFRDSAHYYIKMQDFAERLKRWIEKQPWKPNVKNMVLSWIEEGLEERAITRDLNWGIPVPLDEEDMKGKVLYVWFEAPIGYISITIEHFKRIGKPNEWKKYWLNIDGQTRVIHFIGKDNIPFHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPANEYLTLEGKKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRDSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVPERGELDELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIVKALGILLEPFLPDASEKIWHLLNLDEVKRWEFRELPAGHKVRKPEILFKKVTDDQIIYFILNYMAKGNPEGARILLDKYYKREDVIRVAKEKFGDEAEVVLRRVYKDIKLKEKKEGKEMYVKFDDFAKLDLRVGKIIEVKDHPNADKLYVVKVDLGDEVRTLVAGLKKYYKPEELLNRYVVVVANLEPKKLRGIGSQGMLLAADDGERVALLMPDKEVKLGAKVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR120_YEAST
Sequence: MNILKHFPSYVGPSKIRTLVIPIGHWTRKEFNNAVQKLSEFNEIHLSDVTPIDSPIFTPQGFPHGKLFFDFLTIDHDDALELFLYDFEPFRKTFVIIGLVNDYSDPLTNLNFMKEKYPTLISPNLVYASSTPTKELEQTIDTMENVFASSPDMQKNIETIMCDIARNFLTALNSYYSSYKHVTLRSPGAIGGNAVLKTTLIRQNSYTSSSSSTPMSAVQSSVSSSSKAGSVTTASKRLSSFEMTTNSLKRSASLKLATTLSTSENRSQQKSLGRQMKILGNFQLLAGRYVDALNSFVDAITTLYKVRDYLWLGSALDGISICFLLLSYLGLSYQIPQIVSLICPVEKLNFESSSTGISPVDSNSKATASTTASSTPRNSISIAAMQSPRNSIMSLSAPALNIDVENINLPLLIKCISDKVLYYYDLSLMHNSEYAPQVVYCEFLLKTLTFMTSCYKSSEFSKDVLDNIVKNQHRALSDIPNSPMFPRFEVYFYSNKLFELQLKEMQVEAQIKIYSTMAEVYRLLGYKRKQLFVLRLLMVALLATPNKIAWHPDYRTLIDTIIELLNINESEAKINVDDPSQSTWLILQKKILQLCIKVSRKINDFEYVAKFSSILITKYTHLLNQSEQDALFKEYIQPSITNESITSYWDPFILREVVINRILDSDPTSNEIPLESDVSSLESLENRQKTQDINPQEVFNPFKRVQPTSFVSNNSTKVPILVFLVGDKAEFTCRVQNPFKFDFTINDIQLDEEISEFCEIDRKAVSYSGPYNVKAESIRSITLPLIIKKPTYKKIYEISCLKISILKLPLQKFDIINDSRRSNPVEEEAEYSKCIYGKLKIKILPEQPQLELLSTSKMTRNSWMMLDGTKTDFHITVRNKSLSCAINHIKIIPMNNIEQMLKPDYWKKMPPDDLYIMEKQLDWLSKSCVRIIKLPTVIKPNETITFDLELDNTAVPFNFTGFDLLIEYGMSATDESCIYLKKLSIPYEVTLRRTIEVPSMDIIPLNELFSSQVENVDWIEYVMSKIRAESNLHSRDFILLLLDFRNSWIDGIKLNVQFEDFTSNEYHVEASHTSRIIVPIKKIDYKKYNFENTPIPRIYPGRQFIQSGLNEEQTIEMRQKFWCREHIISKLKCNWKLTTDQSVTGSVDFNKFIEKFDHKMVYTIYPGRLFYGVQLLLDEPKVKVGEIINLKIITEPTSTCRRKQNSTVNFLDIVIFDSKTSKILPRSNRRILYNGSLTKPISTTKVSEINLEIIPIEKGRYEFSVCISKSNNQDGIIQFDSENVILSVI
What is the function of this protein?
Specific subunit of the TRAPP II complex, a highly conserved vesicle tethering complex that functions in the late Golgi as a guanine nucleotide exchanger (GEF) for the Golgi YPT1 GTPase.  TRS120 plays a role in the YPT GEF activity of TRAPP II in concert with the two other TRAPP II-specific subunits TRS65 and TRS130.
What are the official names of this protein?
Trafficking protein particle complex II-specific subunit 120, TRAPP II-specific subunit 120, Transport protein particle 120 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRS120 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network.
Protein: KRP1_SCHPO
Sequence: MHPALLCGPILAIFLQFLVSSCSPLENDDLFLVQVEPEVDPVVAAEAIGAKYVRPLLNLKYHHLIKLHKGSDDSVQSSIRKRGIDAGILELERQTPRWRYKRDASESDELLNEFSNHFGISDPLFYGQWHIFNSNNPGHDLNLREVWDAGYFGENVTVAFVDDGIDFKHPDLQAAYTSLGSWDFNDNIADPLPKLSDDQHGTRCAGEVAAAWNDVCGVGIAPRAKVAGLRILSAPITDAVESEALNYGFQTNHIYSCSWGPADDGRAMDAPNTATRRALMNGVLNGRNGLGSIFVFASGNGGHYHDNCNFDGYTNSIFSATIGAVDAEHKIPFYSEVCAAQLVSAYSSGSHLSILTTNPEGTCTRSHGGTSAAAPLASAVYALALSIRPDLSWRDIQHITVYSASPFDSPSQNAEWQKTPAGFQFSHHFGFGKLDASKFVEVAKDWQVVNPQTWLIAPEINVNKSFGSVNNETITEMVSEFTVTKDMIEKSNFKRLEHVTVRVCIPFNRRGALEILLESPSGIRSILASERPYDENSKGFLDWTFMTVQHWAEPPEGVWKLLVNDRSGGKHEGTFENWQLALWGESENPSNTAPLPYDTLELPKEMVLGIYSEPNSDLTNSSTLLSPTSTSFTSYTVSATATPTSTSHIPIPTVLPPTQPVLEPSYREIVAFITFFLLFAFIFVAVIWTWISAFWKAKAPPPLSQQEIA
What is the function of this protein?
Membrane-bound, subtilisin-like serine protease that processes the P-factor precursor and other precursor proteins.  Essential for cell viability.  Cleaves substrate on the C-terminal side of dibasic residues.
What are the official names of this protein?
Dibasic-processing endoprotease, KEX2-related protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
Protein: COXX_LISMH
Sequence: MNQIEKTGELSASRFTVRDFTELVKIGIVNSNTITAFTGMWLAFQLNGISFIQNVDVIFFTIVGSALIVAASGAFNNVIDRDIDGIMERTKNRPTMTGKISGKRALMVALVLGVVGTIMLFMTTWQAGVLGVIGVFLYVVVYSLYAKRKLVSNTVIGSFSGAVPPLIGWFAVEPSFSIVPIMLFLVMFCWQPPHFYAIAIKRKEEYAAAGIPMLPVVKGIERTKKSMFFWVILLTILPFFMFELGIVYVVLATLLNIGWLALSIYGFKMEDSIKWAKWMFVYSLNYMTILFVAMVVISIFL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG3_XENTR
Sequence: MQSVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFLAAGDHLVHHCPTWQWSAGEESKIKPYLPNDKQFLMTKNVPCYKRCKQMEYSDEQEAIIEEDDGDGGWVDTFHHSLTGVTEAVKEITLETQDCGKTTSNIAVDDDDDDDEGEAADMEDYEESGLLDNDDATVDTSKIKEACKPKADLGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRRPLTVENMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8-like proteins (gabarap, gabarapl1, gabarapl2 or map1lc3a).  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8-like proteins from atg3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of atg8-like proteins.  The formation of the atg8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of atg12 to itself, atg12 conjugation to atg3 playing a role in mitochondrial homeostasis but not in autophagy.  atg7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with atg3 (By similarity).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_ROSDO
Sequence: MNAKELHDKTPDQLREELANLKKTSFNLRFQQATGQLENPAQIRKARRDAARVKTILNQKAASAAASE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS7_BURMS
Sequence: MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MURG_SHEON
Sequence: MTDAGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFIDIKGVRGNGLVRKLAAPFKVVRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAAKLAGVPLVLHEQNAIPGMTNKLLSRIASQVLCAFKNTFTQVKAKVVGNPIRRELIALGGEPKQTADEALKVLVVGGSLGAKVFNDLMPEVVAALSKQQSITVWHQVGKDNLAGVKSAYQQQGQDGGVNVAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNAQVLVEAGAAFLLPQAILDVNKLVSKLQLLANDRAELARMGQRARDVAVLDATEQVAQVCIALAEKG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OMPA_SHIBC
Sequence: MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQYHDTGFYGNGYQNNNGATHESQLGAGAFGGYQVNPYLAFEGGYDWLGRMPYKGDQVNGAFKSQGVQLTAKLSYPIYDDLDIYTRLGGMVWRADAKNNVVGGDRRSNHDTGVSPVFAGGVEYAWTPSIATRLEYQWINNIGDAGTVGTRPDNGMLSVGVSYRFGQDEAAPVVAPAPAPAPQVQTKHFTLKSDVLFNFNKSTLKPEGQQALDQLYTQLSNLDPKDGAVVVLGYTDRIGSDAYNQRLSQQRAQSVVDYLVSKGIPAGKITAQGQGESNPVTGNTCDNVKKRAALIDCLAPDRRVEIEVKGVKDVVTQPQA
What is the function of this protein?
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm.  Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
What are the official names of this protein?
Outer membrane protein A, Outer membrane porin A, Outer membrane protein 3A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ERF1_DIDNA
Sequence: MIQSEEDLEYERNVEMFRLKRLIAKLESMKGSGTSMITLIINFKDQINIHARMLAEEVGKASNIKSRVTRQNVTDALTSTLEKLKLYNKTPPNGLVIFCGLVQQEDGGEKMIKIDLEPFKPINTTLYKCDSVFHTEEVRKLLEDNDKFGFIIMDGNGSLFGTLQGSTRTVLLKFNVDLPKKHGRGGQSANRFARIRIEKRRNYLRKVAESTTACFITNDMPNVKGLILAGSAEFKNDLQKSDLFDLRLQPIVIKLVDISYGGENGFNQAIELSSDALKSVKFIHEKKVIGKFFDEIAKDTGKYVFGIKDTLEAMDMGSVDILIIYENLEYNRLILRDANDNIVNETLHKNKCPSGSKYKNETTGVEYEVLDNIPLTEWFMDNYKKYVSHLEIVTDKSSEGSQFLKGFGGIGGILRYKMDTDFDDTENNNEWNDDDFI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA and possibly also UAG and UGA.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPDE1_HUMAN
Sequence: MQKHYTVAWFLYSAPGVDPSPPCRSLGWKRKREWSDESEEEPEKELAPEPEETWVVETLCGLKMKLKQQRVSPILLEHHKDFNSQLAPGVDPSPPHRSFCWKRKMEWWDKSEESEEEPRKVLAPEPEEIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAYFSRAGFPSWQYQRLHFFLALYLANDMEEDDEDSKQNIFHFLYGKNRSRIPLLRKRRFQLYRSMNPRARKNRSHIPLVRKRRFQLRRCMNPRARKNRSQIVLFQKRRFHFFCSMSCRAWVSPEELEEIQAYDPEHWVWARDRARLS
What are the official names of this protein?
Speedy protein E1, Williams-Beuren syndrome chromosomal region 19 protein.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: RL9_STRA5
Sequence: MKVIFLQDVKGKGKKGEVKEVPTGYAQNFLLKKNLAKEATTQAIGELKGKQKSEEKAQAEILAQAKELKTQLESETTRVQFIEKVGPDGRTFGSITAKKIAEELQKQYGIKIDKRHIDLDHTIRAIGKVEVPVKLHKQVSSQIKLDIKEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PGK1_HORSE
Sequence: MSLSNKLTLDKLNVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDVGPMPDKYSLQPVAVELKSLLGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIETFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKNLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV
What is the function of this protein?
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate.  In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).  May play a role in sperm motility.
What are the official names of this protein?
Phosphoglycerate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_RHOPA
Sequence: MSVAIVDYGSGNLHSAAKAFERAARSMENPEPILVTRDPDQVFRADRVVLPGVGAFADCRKGLDSIDGMVQALNETVRDKARPFFGICVGMQLMATRGKEHVTTDGLNWIAGDVVKIAPDREDLKIPHMGWNTLDPVREHPVLEKLPLGPKGLHAYFVHSFHLAAEHEGDVLARADYGGPVTAVVGKDTAIGTQFHPEKSQRFGLALISNFLKWKP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDX2_HUMAN
Sequence: MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVPGSVPGVLGPTGGVLNPTVTQ
What is the function of this protein?
Transcription factor which regulates the transcription of multiple genes expressed in the intestinal epithelium (By similarity).  Binds to the promoter of the intestinal sucrase-isomaltase SI and activates SI transcription (By similarity).  Binds to the DNA sequence 5'-ATAAAAACTTAT-3' in the promoter region of VDR and activates VDR transcription (By similarity).  Binds to and activates transcription of LPH (By similarity).  Activates transcription of CLDN2 and intestinal mucin MUC2 (By similarity).  Binds to the 5'-AATTTTTTACAACACCT-3' DNA sequence in the promoter region of CA1 and activates CA1 transcription (By similarity).  Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.  Binds preferentially to methylated DNA (PubMed:28473536).
What are the official names of this protein?
Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABH_NEOSM
Sequence: MKKTNFLSFGCYLPKKVLTNFDLEELVDTSDEWILRRTGIKTRYIAEEEDVCELAFRASLNCLERAMHFSQKEVDAIIVATCTANKRLPAVANMLQARLGIGRHILSFDVNAACTGFLYALSIVDAMIVSGKVSTVLLVGAEAMSTIIDWNDRNTCVLFGDGAGAVLVSAGDSGGVLYEHMACDSSLGEALLAEVGGTLKMDGRSVFEAAIKRLTLAIGEALKTTGISVEELDYFIMHQANIRIIELIGEKIGIDRSKIIVTVDRYANTSAASIPITLAYMDSHGSIRKGAKILFAAMGAGFTYGVTIFEY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_VIBPA
Sequence: MNQKDTRKETLEFNKLQKRLRRNVGNAITDYNMIEEGDVVMACISGGKDSFAMLDILLNLQKAAPIKFEVVAVNLDQKQPGFPEHILPEYFETLNIPYYIVDKDTYSVVKEKVPEGKTTCGLCSRLRRGTLYSFAEKIGATKLALGHHMDDIVETMFLNMFHGSRLKAMPPKLRSDDGRNVVIRPLTYCREKDLIKYAEHKDFPIIPCNLCGSQENLQRQAIKAMLIDWDKKTPGRVEAIFKSIQNVSPSQLADRELFDFVNLPLDRDGSREEYEFSEAVVSSTNIDESLFIDVTNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA1_NITOC
Sequence: MYIVMITPECAPIAKVGGLGDVVQGLSNELSIRGNTVELILPKYDCMRYERIWGLEKTHNNLWVPYHDQWIPCDVYFGFAEGLKCFFIEPHNGFFQRGTYYGQPDDPQRFAFFCKAALEFMLRSNKYPEIIHCHDWQTGLVPVLLFEQYKYLGMTHPRVCYTLHNMRHQGVTGGHILQQVGLDPAAYMTPERLLDHTYPHGVNLMKGGIVFSNFITTVSPRYLDEIRYTDQGYGLQHTLHEHSQKLGGILNGVDYKVWNPDIDPYIAARYNLKTLDKKYENKTALRHRLWLRDEYKPIVGVISRLDPQKGVELIRHALFYCLANGCQFVLLGASASNSINADFWYLKQYLNDDPDCHLEIGYDEDLAHQIYAGADMLIVPSIYEPCGLTQMIAMKYGTVPIVRHVGGLADTVFDANYAHKPYHERNGFVFHDFNHEGIEAALHRAIGLWYEYPQYFRELMENGMRYDFSWNHPGQHYLNIYHHIQEI
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 1, Starch [bacterial glycogen] synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: CGOX_MYCBO
Sequence: MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
What are the official names of this protein?
Coproporphyrinogen III oxidase.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STAS1
Sequence: MPKMKTHRGAAKRVKRTGSGKLKRSRAFTSHLFANKSTKQKRKLRKASLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GYRB_TREPA
Sequence: MGIEYSASSITVLEGLEAVRKRPGMYIGSTGPNGLHHLVYEVVDNCIDEAMAGYCDRITVVLEQGNVVRVEDNGRGIPVDVHPHEGVSALEVVLTKLHAGGKFDKKSYKVSGGLHGVGVSVVNALSLWVEVTVYRDGAEYYQKFNVGMPLAPVEKRGVSEKRGTIIRWQADPSIFKETVAYDFDVLLTRLRELAFLNSTVVIQLRDERLATAKQVEFAFEGGIRHFVSYLNRGKSVVPERPLYIEGSKSDVLVEVALQYHDGYTENVQSFVNDINTREGGTHLEGFKSALTRVANDFLKKSPKLAKKIEREEKLVGEDVRAGLTVVLSVKIPEPQFEGQTKTKLGNSEVRGIVDSLVGERLTLYFEQNPGVLTKILEKSIAEAQARLAARRAKEAARRKSGMDSFGLPGKLADCSLKDPAKCEVYIVEGDSAGGSAKKGRDSKTQAILPLWGKMLNVEKTRLDKVLHNEKLQPIIATLGTGVGKDFDLTRIRYHKVIIMADADVDGSHIRTLLLTFFFRYLPQIIEAGYVYLAMPPLYRIAWSKKELYVYSDTERDEALESIGKKSGVAVQRYKGLGEMDGTQLWETTMNPVRRKMMQVVLSDAVEADRVFSTLMGEDVEPRRKFIEENAIYARLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACL_SALG2
Sequence: MDYEFLRDVTGGVKVRMSMGHEVVGHWFNEEVKDNLSLLDEVEQAARTVKGSERSWQRAGHEYTIWMDGEEVMIRANQLDFSGDEMEEGMSYYDEESLSLCGMEDFLRVVAAYREFVSKA
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: Y6366_TRIVH
Sequence: MHVSTLLVAVLLPLALSKPTPRKKTSSFKVHLARRGETEYYRDGPTDLQRAYAKYGIPTTHEMEGYHPQPISKLPGNSKATAGSGKEGVESQDEKGEVVNNPTDHDIQFLSPVTIGGQPFIMNFDTGSSDTWVMNTQMTDEEAKKDHHLYDPSKSKTASKLVDQNFDIKYGDKTHASGPVYSDVMDIGGATVRNQAIGLPSKVAASLAEDKTSDGLVGLAMTKLNTIRPVKQKTFFENLAEDLDEPVFTAQLRHGKMGSYEFGAIDKSKYHGDLIKVPVINENGFWEIPCSLYSVGKLDKIQTIQNGTGTAILDTGTTLLVLDEKIVKAYYAQVPGARYDPTRFAGWVYPCNSPMPSLFLAVGTDHMAIIPSSLLTFQSYGPGPDGVETCYGGLQSNNAGGIQILGDVFFKALFVVFDQRGPSISLAPHA
What is the function of this protein?
Probable secreted aspartic-type endopeptidase which contributes to virulence.
What are the official names of this protein?
Probable aspartic-type endopeptidase TRV_06366.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACPX_STRRM
Sequence: MTLLTLSDLLTLLRECAGEEESIDLGGDVEDVAFDALGYDSLALLNTVGRIERDYGVQLGDDAVEKATTPRALIEMTNASLTGASPSAGGAARDK
What is the function of this protein?
Acyl carrier protein.
What are the official names of this protein?
Oxytetracycline polyketide synthase acyl carrier protein, ACP.