PharMolix/UniProtQA huggingface dataset:
Protein: RL22_STRP7
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PYRB_ERYLH
Sequence: MTSDGTPTQSGRYPAGGHAFPHGSLTGIAQLERHEILYLLDEAEQWVDFNRQSEKHCDLLAGLTIINAFFENSTRTLLSFEIAGKRLGADVVNMHAAQSSVKKGETLIDTAITLNAMRADAIVIRHGSSGAVDLIASKVDCPVLNAGDGQHEHPTQALLDALALRHALEARGEGSEDFTGLTITICGDILHSRVARSNILCLQAMGASVRVCAPPALMPVGIERMGAEPFHDFDAALKGCDVAMMLRLQTERMSGQFIPSAREYHHLYGLTQHRLQRCAPDALVMHPGPMNRGVEIDSDVADMLDRSIITRQVEMGVAVRMACLDILTRKGRGLPGWQGDLGKGQWA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FH10_ARATH
Sequence: MDGLCYVIFIIFSLLSCAFSPLSYASPATFSRRHLLQAPVTDPSTFSPPFFPLYSSTSPPPPPSPPQPLPPPAPTFATFPANISALVLPRSPKPQTPSRTLLIPAISAVLAAATLIALAFFFYGRWRGQTSHFKDESKSLASDISQSQQQTLPCPPPRNNNTQNKLSVAPSTSDVLYLGNVVTSSGSGFVKPESPDISPLPPLPARSFLLQHHSEANLDEEEEDDDFYSPLASIAGQESRDRRINPYSNCSCSISSHSDSPAMSPSAAMSPPMNSTAPHWSTNQNTHSPSSPERTVRNNKRYGGQSLRMFSLWNQNLGFPRISSASTSPERGMIRTPDAYARSSMYSSVSTTPDRFFRKVLDSSPPRWNDFSRNVKSLFLSSTSASPARDFCINISESSRSLKSSWEKPELDTTQQRESAAAAVTLPPPQRPPPAMPEPPPLVPPSQSFMVQKSGKKLSFSELPQSCGEGTTDRPKPKLKPLPWDKVRPSSRRTNTWDRLPYNSSNANSKQRSLSCDLPMLNQESKVLDPRKSQNVAVLLTTLKLTTNDVCQALRDGHYDALGVELLESLARVAPSEEEEKKLISYSDDSVIKLAPSERFLKELLNVPFVFKRVDALLSVASFDSKVKHLKRSFSVIQAACEALRNSRMLLRLVGATLEAGMKSGNAHDFKLEALLGLVDIKSSDGRTSILDSVVQKITESEGIKGLQVVRNLSSVLNDAKKSAELDYGVVRMNVSKLYEEVQKISEVLRLCEETGHSEEHQWWKFRESVTRFLETAAEEIKKIEREEGSTLFAVKKITEYFHVDPAKEEAQLLKVFVIVRDFLKILEGVCKKMEVTSSLA
What is the function of this protein?
Might be involved in the organization and polarity of the actin cytoskeleton.
What are the official names of this protein?
Formin-like protein 10, AtFH10.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FABV_CLOPS
Sequence: MIVEPKFRGFICTTSHPIGCKKNVENQIEYVKENGKIEGAKRVLVLGASTGYGLASAIVASEACDAEVLGVSFEREAKGKRTASAGWYNIESLKKFVEGEGKKFISVNGDAFSNEVKSEVIDLIKENMGKVDLVIYSLAAPKRKDPVSGEVYSSCLKTVGAPFTSKTLDFHTGEIQDITINPATEEEIEGTRKVMGGEDWMLWIEALKEANVLENGVKTIAYSYIGPEVTYPIYREGTIGRAKNDLEKTAGEITKVLKSLNGEGYISVNKALVTQASSAIPIVSLYISILYKVMKEKGTHEGCIEQIYRMFKELYEGNLNLDSENRIRIDDLEMAEDVQKAIEEIWPQITSENVFELSDAEDFKKEFFKLFGFGLEGVDYSEDVDITTV
What is the function of this protein?
Involved in the fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
What are the official names of this protein?
Trans-2-enoyl-CoA reductase [NADH], TER.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: DEOC_MYCTA
Sequence: MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRA_STAES
Sequence: MVLFIILAILVVILIAIGVLFYMRSNKRNLIEKTEERKNEIEQLPLDDNLRKLTGLNLKGETKTKYDAMKKDNTETTNKYLAPVEEKIQNAEELLEKFKFTAAQTEIDDAHELMDQYEENYQHQVTQVDDIINLHKENEALYEKCKVDYREMKRDVLANRHQFGEAAEPLENEIENYEPKLNEYENLKSEGNYVQAHNHIAALEDQIKNLKSYMDEIPELIRETQKELPGQFQDLKYGCRDLKVEGYDLDHVKVDGTIQSLKTELSFVEPMISRLELDEANNKLENINDKLDEMYDLIEYEVKAKNEVEETKDIITDDLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKETSKSAVRYSEVQDNLQYLEDHVSVINKEQDKLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDNEVREVNEQFRERPIHVKQLKDKVAKIVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDHHHVDKSLNEAERLFKNNRYKRAIEIAEEALESVEPGITKHIEEQVIKE
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: PIP_GORGO
Sequence: MRLLQLLFRASPATLLLVLCLQLGANKAQDNTRKIIIKNFDIPKSVRPNDEVTAVLAVQTELKECMVVKTYLISSVPLQGAFNYKYTACLCDDNPKTFYWDFYANRTVQIAAVIDVIQELGICPDDAAVIPIKNNRFYTTEILEVE
What are the official names of this protein?
Prolactin-inducible protein homolog, Prolactin-induced protein.
What is the protein family that this protein belongs to?
Belongs to the PIP family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_GEOSW
Sequence: MKRTYQPNKRKRSKVHGFRARMSTRNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GCST_SALAR
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLAWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTEEQRNAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPTDRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: Y2915_MYCTO
Sequence: MKRVDTIRPRSRAVRLHVRGLGLPDETAIQLWIVDGRISTEPVAGADTVFDGGWILPGLVDAHCHVGLGKHGNVELDEAIAQAETERDVGALLLRDCGSPTDTRGLDDHEDLPRIIRAGRHLARPKRYIAGFAVELEDESQLPAAVAEQARRGDGWVKLVGDWIDRQIGDLAPLWSDDVLKAAIDTAHAQGARVTAHVFSEDALPGLINAGIDCIEHGTGLTDDTIALMLEHGTALVPTLINLENFPGIADAAGRYPTYAAHMRDLYARGYGRVAAAREAGVPVYAGTDAGSTIEHGRIADEVAALQRIGMTAHEALGAACWDARRWLGRPGLDDRASADLLCYAQDPRQGPGVLQHPDLVILRGRTFGP
What are the official names of this protein?
Uncharacterized protein MT2982.1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily.
Protein: Y270_CAMJE
Sequence: MPLVNIKLAKPSLSKEQKAELIADITELLSTKYNKSKERVVVVLEDVENYDIGFGGESVEAIKAKASK
What are the official names of this protein?
Probable tautomerase Cj0270.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: NU4M_SQUAC
Sequence: MLKILVPTIMLFLVTWSSPKKWLWPITTTHSLLIALLSLLWFKWNMDMGWDFSNHYLAIDPLSAPLLILTCWLLPLMILASQNHISTEPIIRQRIYITLLISLQTFLIMAFSATELIMFYIMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLIGSLPLLVALLLMQNDLGSLSMIIIQYPQPLSLSTWADKFWWTACLIAFLVKMPLYGVHLWLPKAHVEAPIAGSMILAAVLLKLGGYGMMRIIVMLNPLTKEMAYPFLILAIWGVIMTSSICLRQTDLKSLIAYSSVSHMGLVAGAIMIQTPWSFAGAITLMIAHGLVSSALFCLANTNYERTHSRTLLLARGIQVMLPLMATWWFIANLANLALPPTPNLMGELLIISSLFNWSSWTILLTGLGVLITASYSLYMFLMTQRGPASQHLLSLNPSYTREHLLLNLHLIPMLLLILKPELIWGWTF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CITA_ECOLX
Sequence: MTQQPSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIAKTFFPAESEFAALMLTFAVFGSGFLMRPIGAVVLGAYIDRIGRRKGLMITLAIMGCGTLLIALVPGYQTIGLLAPVLVLVGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYGLNVTLGHDEISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFTTIAKNWRIITAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLVVTMLVGISNFIWLPIGGAISDRIGRRPVLMGITLLALVTTLPVMNWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVQLTGDKSSPGWWLMCAALCGLAATTMLFARLSSGYQTVENKL
What is the function of this protein?
Uptake of citrate across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
Citrate-proton symporter, Citrate carrier protein, Citrate transporter, Citrate utilization determinant, Citrate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_HERAR
Sequence: MDIKQYMKEVGQRARKASRAMAKADTAAKNQALSLIAAAIRRDADILRAANQVDLVAARLNGLEPAMLDRLTLSDKAIATMAEGLEQIVALPDPIGEISNMKYRPTGIQVGQMRVPLGVIGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVSEGLAGAGLPADAVQIVETTDRAAVGELITMPEYVDVIVPRGGKGLIERLMKESKVPMIKHLDGICHVYIDDKADPAKALDIAFNAKCHRYGTCNTMETLLVARAIAPTILPALAKLYATRDVELRGDDEARAILQGYAHLAAASAEDWSTEYLDAILSVKIVADMDEAIDHINTYSSKHTDSIVTEDYTRAMRFLREVDSASVMINASTRFADGFEYGLGAEIGISNDKLHARGPVGLDGLTSLKYVVFGHGEVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLX_PSEPU
Sequence: MTMTMHLGLDYIDSLVEEDENEGIYRCKREMFTDPRLFDLEMKHIFEGNWIYLAHESQIPEKNDYYTTQMGRQPIFITRNKDGELNAFVNACSHRGATLCRFRSGNKATHTCSFHGWTFSNSGKLLKVKDPKGAGYPDSFDCDGSHDLKKVARFASYRGFLFGSLREDVAPLEEFLGESRKVIDMVVDQSPEGLEVLRGSSTYVYEGNWKVQVENGADGYHVSTVHWNYAATQQQRKLRDAGDDIRAMTASSWGGDGGGFYSFENGHQMVWARWGDPKNRPLFAERDRLASEFGEARADWMIGVSRNLCLYPNLYLMDQFGSQLRITRPLSVDRTEITIYCIAPKGETPRRARRVRQYEDFFNVSGMATPDDLEEFRACQEGFAGGGMNDMSRGAKHWIEGPDEGAKEIDLHPKLSGVRSEDEGLFVMQHKYWQQQMIKAVKREQDRLIHAEGV
What are the official names of this protein?
Toluate 1,2-dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: RL13_VIBVY
Sequence: MKTFVAKPETVKRDWYVVDAEGKTLGRLASEIASRLRGKHKAEYTPHVDTGDYIIVINAEKVTVTGNKAAAKTYYRHTEFPGGIKSITFDKLIVRKPEMVIELAVKGMLPRGPLGRAMYRKLKVYAGAEHNHVAQQPKVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: XGPT_BUCAP
Sequence: MSEKYIVTWDMLQIHTRILAHRLLKTKNAWNGIIAVSRGGLVPSAILARELGIRCVDTVCIASYNYDCLQKNRKIIKKARGDGEKIIVVDDLVDTGGTAKIIRNLYPKAYFVTIFAKPLGRLLVDDYIIDIDQNIWIEQPWDMSISYISPLIKK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PEP2_EMENI
Sequence: MPNLHSLPLGTRPENAIRNNGPDNLVLERAKLRELAEGWPCYRDACEWENFESIFHPDAVVYTTWSGRVGYKDFIAGSKAGMDNGAFIMHRCHGATTDITADATRAVTKLKATITQRFVIDGIEVDAEADCRFCFFFEKADVDGKGPRWGARFVRHWYEKDKLLPVVPGRFPKIDVDKLNSYPEGYKCLVYCQELTMGVKVLQDMPGHRRHAGTLSGEKHDLLYRLAKDWLDGKEIDV
What are the official names of this protein?
Uncharacterized protein AN9274.
What is the protein family that this protein belongs to?
Belongs to the PEP2 family.
Protein: SNMP1_DROWI
Sequence: MQVHRMKLLMGSGGGLLFGIIFGWVIFPKILKFMISKQVTLKPGTDIRDLWSATPFPLHFYIYVFNVTNPDDVARGARPQLQEIGPFVFDEWKDKFDLIDDVVEDTVSYNMRNTFIFNEEASSPLTGEEIITLPHPLMQPIGITVQRERAAMMELISKALTLVFPDATAFYSGKFMDIFFRGLDVDCSSEEFAAKALCTVFYTGEVKQAKQMNQTHFLFSFMGQANHSDAGRFTVCRGVKNNMKLGKVVKFADEPELDAWPGDECNQFVGTDSTVFPPGLKREAGLWAFTPDICRSLGAMYQRKSSYHGMPAVRYNLDLGDVRSDEKLHCFCDDPEDLDTCPPRGTMNLAPCVGGPLIASLPHFYKADPKLVAAVDGLNPNEKDHAVYIDFELMSGTPFQAAKRLQFSLDMEPVEGIEPMQKLPKLILPLFWVEEGVHLNKTYTNMVKYTLFLGLKFNSGLRWTIITMSLVGLMSTAYLFYQQYDSLDITMPPKIIKESNKVADEVESSKSKTIEQNSSITTSLPGANQSHHKDRY
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSA_MYCGI
Sequence: MSTTEESAKLFADASSVIPGGVNSPVRAFNSVGGTPRFITSAKGCRLTDVDGNQYVDLVCSWGPMILGHAHPAVVEAVQRVAAHGLSFGAPTPSESELAREIIDRVAPVERVRLVNSGTEATMSAIRLARGFTGRAKIVKFSGCYHGHSDALLADAGSGVATLGLPSSPGVTGAAAADTLVLPYNNVAAVEEIFAQFGDEIACVITEASPGNMGTVPPLPGFNAALRRITAAHGALLIVDEVMTGFRVSRSGWYGLDPVDADLFTFGKVMSGGLPAAAFGGTAEVMGRLAPLGPVYQAGTLSGNPVAMAAGLATLRAADDAAYAKLDANADRLVGLIGDALTEAGVTHQIPRAGNMFSVFFGGDPVTDFASAKATETWRFPAFFHALLDAGIYPPPSAYEAWFVSTALDDEAFDRIADALPGAARAAAQAAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_PRUAP
Sequence: FRGHDKKDKKIQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SECB_SINMW
Sequence: MTTDSASNGNGSAQQPSPSLNILAQYVKDLSFENPGAPRSLQARDRSPAININVNVNANPLAENDFDVVLSLSAQAKDGDKMLFNVELAYGGVFRVAGFPQEHMLPLLFIECPRLLFPFARQIVADATRNGGFPPLMIDPIDFAQMFAQRMAEEKVRAQVANTNDTAN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_STRP8
Sequence: MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVAFFDKYVPVLHENNVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQDVLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTPVLWPDFKKAELLKAIADYNRRQRRFGKV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: SDHB_COXBU
Sequence: MTFSIMRFNPETDKKPYMQDFELDVSAIQGKMLLNALEALREKHPDIGLRRSCAEGVCGSDGMNINGKNALACVTQLKDLPDRVVVRPLPGFPIIRDLIVDMEQFYAQYKKVKPYLLNDQEAPQKERLQSPEERAKLDGLYECILCACCSSSCPSYWWNPDKFIGPAGLLWSYRFIADSRDSKEKERLDAMKDPYSVFRCRTIMDCATVCPKNLNPAKAIRKIRTEMLQETESGE
What are the official names of this protein?
Succinate dehydrogenase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
Protein: MYC_HYLLA
Sequence: MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSPRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSSSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASPDSSAFSPSSDSLLSSTESSPQASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPSKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQGEEQKLTSEKDLLRKRREQLKHKLEQLRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: TIR1_ECOLX
Sequence: MPIGNLGHNPNVRALIPPAPPLPSQTDGAGGARNQLINSNGPMGSRLLFTPIRNSVADAADSRASDIPGLPTNPLRFAASEVSLHGALEVLHDKGGLDTLNSAIGSSLFRVETRDDGSHVAIGQKNGLETTVVLSEQEFSSLQSLDPEGKNKFVFTGGRGGAGHAMVTVASDIAEARQRIIDKLEPKDTKETKEPGDPNSGEGKIIEIHTSTSTSSLRADPKLWLSLGTIAAGLIGMAATGIAQAVALTPEPDDPITTDPDAAANTAEAAAKDQLTKEAFQNPDNQKVNIDENGNAIPSGELKDDVVAQIAEQAKAAGEQARQEAIESNSQAQQKYDEQHAKREQEMSLSSGVGYGISGALILGGGIGAGVTAALHRKNQPAEQTITTRTVVDNQPTNNASAQGNTDTSGPEESPASRRNSNASLASNGSDTSSTGTVENPYADVGMPRNDSLARISEEPIYDEVAADPNYSVIQHFSGNSPVTGRLVGTPGQGIQSTYALLASSGGLRLGMGGLTGGGESAVSTANAAPTPGPARFV
What is the function of this protein?
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection.  The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface.  Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).
What are the official names of this protein?
Translocated intimin receptor Tir, Secreted effector protein Tir.
What is the protein family that this protein belongs to?
Belongs to the Tir receptor family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system (TTSS). Released into the host cytoplasm via TTSS and then independently inserts into the plasma membrane from a cytoplasmic location. In host cells, localizes to the tip of the actin pedestal.
Protein: DNAJ_KLEP7
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEILTDAQKRAAYDQYGHAAFEQGGMGGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGSKPQTCPTCHGAGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVEKTKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHAIFEREGNNLYCEVPINFTMAALGGEIEVPTLDGRVNLKIPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLKELQESFGGPTGENNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PROMS
Sequence: MHIVVVGLSHRTAPVEVREKLSIPDQSITESLKALKAFSDVLEVSILSTCNRMEIYALVKDKNTGISSIKEFISEYSGIIFEDLNPHLFCFRQEEAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGTGAVSISSAAVELAQLKIGQEKGFDTLVSLESENVLVVGAGRMSRLLITHLKSKGCHKLILLNRNIDRALNLAQDFPDLEIVCRGLNELEENISLSSIVFTSTASEEPIIDLAKIEKLNLSNRLKFIDIGVPRNISNDVKQHQFVKSFDVDDLQEVVSRNQEFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKILHTPVTKLRSPQSREERQVSLKIVEKLFSLVEEEQNN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: VATF_CLOPE
Sequence: MDMYKKIGVVGDKDSVLAFKALGIDVFPVVEDEEARKTIDKLAMTGYAVIFVTEHVAKNIEETIERYTRQVLPAVILIPSNQGTLNIGKQRISDNVEKAVGVNIL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.