PharMolix/UniProtQA huggingface dataset:
Protein: PANCY_PROM2
Sequence: MKKVIIRKTEEIENWKRNINNEINFIPTMGNLHNGHIKLISTAKNDNSNVNLVSIFINPLQFDNKLDLENYPKTIDNDIKISFSNGADAIFIPSNEDIYPPNNKNIKFLKAPIELSSALCGLNRIGHFDGVCTVVYRLLNLIKPKNLYLGEKDWQQLLILKNLVLKEKLNVAIKSIPTQRDFDGIPLSSRNVHLSKNERKLIRFFSSELLEAKKNFQQEKNINLNEIIKKLSAKKISIEYLEHLHPHTLQKARLEDNISLLAGAIRCGETRLIDHVFLMKRRPIIAIDGPAGSGKSTVTKLIAKKLKLLYLDTGAMYRALSWLLLKENIDYKKEKKLLNIFKDISIVFKSNTNSHQDVYVNNCCVTEEIRSQKISSIVSKISSIKEVRKFLVEEQRKIGESGGLVAEGRDIGTTVFPNAELKIFLTASIDERAKRRKSDKQSKDSQEIDLDTLKELIEKRDFEDSNREISPLIKANDAIEIISDGYTINEVVDKIIDLYNDKIPKETEIK
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFPA2_HUMAN
Sequence: MWLCPLALTLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKGDPGPPGPMGPPGETPCPPGNNGLPGAPGVPGERGEKGEAGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
What are the official names of this protein?
Pulmonary surfactant-associated protein A2, PSP-A, PSPA, SP-A, SP-A2, 35 kDa pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-5.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: KRI1_DANRE
Sequence: MSDLKINKKFAEKYEKYRQKEELQRLKDRYGDQEEENSSNSSESDSDDSEVELDPKLDRDFYRTLSLLKKKDPKIYQKDAKFYTEETSGSGSDEQPSTSKQSEKPMFLKDYERKVILERGGKYEDDDSADEEISAKMQERAASPTYIQEQKEIQESLRKFVQDSDDEDSDGDGQFLTRRTKTQEEKDKEEADYVEWLKGQTELDEKEELKDMKYLRDYWNNPQLDEKESFLRDFMLNKGYMEEEDEERIPTYNELMQDDVDDSEDEGESFLHKQEDFERHYNFRFEEPDAGKVKTYPRNIATSVRSKDDRRKRKREEVKERKEKEKEQKQQQLKELKNLKRAEIMDKLKKLQELTGNEQLAFNDVDLDGDFDPQQHDQLMQKVFGDEYYEENEEEKPQFEGDEEFEENWNWDTWVGKQQNEEEYDHKEDYTAEEHYQPNCDDPDFIMDADYDPSQQAVSKKKRKKEREEKKKKSKEDVPLMGKKRKKSHFAEIISKSKPVFDPNEKSFEQYLDEYYKLDFEDIIDDLPCRFRYREVVANDFGLSTDEILNAGDKELNRWCSLRKTCMYRSEREELCDLKNFQIKARNVKKKQQVFVSLFNENDGQEEQKDTKGKVGKKRRDRLKKAELTEKSDTTVTEETAEPPPAEQADVQDLKATIANDEEEDDEEFLVPKKKMKTAETVVTKRKEADVERTEKPKRPRKKMRRSGGRRLLKSMTVKMAGREFSRQRLQAYGLNPKRLHFRELYRQKRKEREKQEKQQKKSKQ
What are the official names of this protein?
Protein KRI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the KRI1 family.
Protein: SYS_BORA1
Sequence: MLDPILLRKDLQTVVDRLQSRGVSFDTERFNDLESRRKLVQTETEALQARRNALAKQIGQLKAKGEDASAVMAESQALPGQLKQLEESLAMLQQQLNELLMSVPNLPHASVPVGASSDDNVEVRRWLPAEAGADGNPAPLGFAPRDHVAIGEPLGLDFDTAAKLSGARFSFMRGQMARLHRALAQFMLDLQTGEHGYTECYTPYIVNSSTLYGTGQLPKFKDDMFFVTKGGGDDDPKVDEQGKPLAREDQYLISTSEITLTSVVRDTIVPGDVLPLRMTAHTPCFRSEAGSGGRDTRGMIRQHQFDKVEMVQVANPEQSYDALEQMVGHAEEVLRRLGLPYRVMLLCTGDMGFGAAKTYDLEVWLPAQNTWREISSVSNCESFQARRMQARFRADAKSKPEFVHTLNGSGLAVGRALVAVLENYQQEDGSVRIPEALRPYMGGIEQLKA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCRE_SCHPO
Sequence: MSKKKPIVQYYDPFDLWPSIATDIESKIPLRNLQWVESYQYKKHTITSLDLEFLPWLEEFSSQDTSKDPTLLNIPLVNMLFLPEQDGEIYKTQHKPLATKWFQKVSKNENQSWMIVLVAEAQQAKRSNSLRRTHSRSSSYFAVKSTIDRVRGDFNTGNINHCVRLDYVRFGTPDAEGWNEFLKCLEWAVLSSLDSRFLQLSEQIRSIKLFDSSIFSDYLLFFLQKERLAASFFDLVLYRESLEQCEDMFSTLSKIISAIDGKKENISKYLGEGSDAQPDLKDFNSSFLILGSRYNTLHNLLADGDFTLFHFTLFLLSKIILLNLKISDYEKAFSTLQQALLFLTSSFFNEFVQNNLEIIAAFNYDCYTLLFKKITEAIHNNDTPIPLCCAKILLYARRQLTRMARWNNLIDDSSPLLWREPSFPLIEHHDNSLLDNRFQKLSETISSTSSFLSEYYRLSSEALSIFKAYKNRYSFVNTACDTGLAQYLLEDYENAYASLKNVDVQTAWSNDPLEEKWSKFYVDLLEKLEKFDEALEFASAISKGKVSIYNKNKILELSKKTAKSKVWNLDDFFTIEIPHMMAVVPHDDGINLSFMCESKVFDLESVDSVTCNYVLSSSKNPMNLLFTLHNSITDGKLNVHCNDIIPGRYHLKTIVFKLKDSVLSFQKDCLHSNKQIEVLNPTKHSNHLYILQSKISQQFQNDGIFACIPIMFGERFYKASCSEIKLSYIENSGFTNLEKSFLSEESHCGLESKTDSLVIKNIQKVPGVAKLYIPLTNTPVEGNEFLINLSYILESGQTVRFGKVLHIENAGIVEANCEKTNNMRDPLTSTIFLHIQPKEPIIFCSWNCMRKTKQGTYDNVFDIPYNIPVLSPMDCFTSCHFDSDMSIDLKFSMNCLRLADVVFMKLCVNIWERFDFIDIEHIMPLLDHACQQISLSNITQGTVVLPEEIRKLNGKKILNSFFDNEELRNEFSEFIQHLESEVSFNSLRSFVQEFEKKERLKNLPFYFSLHQTIGPLPFKDEMQSTTIEYIWKIPQKVLLNKPTEITLTFLRSLTHSKKEKQGQSFEIFYNFPAYTTTILFAGPTQRKIVWEKNQTTAQEQVTAVFLTAGRVMLPEVVVHSKDDDISILKNTKYTLVGRPLNDQPDLDYAP
What are the official names of this protein?
Uncharacterized protein CC285.14.
What is the protein family that this protein belongs to?
Belongs to the TMEM1 family.
Protein: DACB_MYCGE
Sequence: MVVNILLFITLIFLLLLFVFLIAFAFLNKRVRNYVVRTWTSVFSKSKQNLDKKNFFDNLTSTLLRLSVDKIGAIIAIEKRDSLDPYINIGYRVSSDFSPELLVTIFYNKSSPLHDGAVIVRDYKIISVSSYFPMTRQLIDVSYGSRHRSALGLSEKSDAVVFIVSETTGKISVALKGVIKTLSSNSDRLQDEIIHYLSSK
What is the function of this protein?
Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
What are the official names of this protein?
Diadenylate cyclase, DAC, Cyclic-di-AMP synthase, c-di-AMP synthase, Diadenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FABA_PSEP1
Sequence: MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISEEGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPEAKKVTYNIHIKRVLKGKLNMAIADGSVSVDGREIYTAEGLRVGVFTSTDNF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_CLOBB
Sequence: MKFTKTNDLRDAYLNFFESKDHLKLESFSLVPQNDKSLLLINAGMAPLKPYFTGLQEPPKKRITTCQKCVRTGDIDNVGITSRHGTFFEMLGNFSFGDYFKKEIIPWAWEFLTGVLELPKEKLYVTIYLDDDEAYEYWTTLTDVDKSHIFRLGKEDNFWEHGAGPCGPCTEIHFSRTDEVPKNSEEFVELSDADKIIEVWNLVFTQFDGDGKGNYEKLASTNIDTGMGLERLAVVMQNKNSIFEIDTLENILKEVGNLASVKYGEDNKIDVSLRIITDHIRSITFMISDDIMPSNEGRGYVLRRLLRRAARHGKTLGIKDAFLCNLCDVVIRDCSSAYPDLEVKKEYIKKVIKIEEDKFRETLDSGMEILNNLISELKENNEKVLKGADGFKLYDTFGFPMELTKEILEDEGLSLDEDGFHEEMKEQRERARSARKTSNYMGTDVKTLDIISSEIETTFDGYENDSLIAEVKTLVNGEDFADSITEGDNAVVVTDVTPFYAEMGGQIGDTGTIYNDNFKGKILDTKKNIGGKIIHFVEAISGELKVGDKVTLEVDNARRENIKKNHTATHLLDSALVKVLGSHVHQAGSYVSADRLRFDFSHFEGVKEEELLKVEQLVNEAIMSVTPVNTTEMDLQEAKNSGAVGIFDDKYAEKVRVVCAGEYSKELCGGTHIDNTGKIGLFKIISENGIAAGTRRIEAVTGMEAYKLVNEKAELLKQISGKLKCSEKEITSKLDQQSKEMKEKEKEITILKSKFASMEINDIINSAKDVKGINIVAYALKDVDGEALRGLCEKVRDNVNNSLTLLTSSVDGKVVICAMADKEAVSKGAHCGKVIKEVATILGGGGGGRPDMAQAGGKLPEKISEALDSVYKIVETLVK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_CHLPN
Sequence: MSLPLVLGSSSPRRKFILEKFRVPFTVIPSNFDESKVSYSGDPIAYTQELAAQKAYAVSELHSPCDCIILTGDTIVSYDGRIFTKPQDKADAIQMLKTLRNQTHDVVTSIAVLHKGKLLTGSETSQISLTMIPDHRIESYIDTVGTLNNCGAYDVCHGGLILKKVHGCVYNVQGLPIQTLKYLLEELNIDLWDYSI
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_ACIC5
Sequence: MEVILKEDIETLGHRGDIVKVADGYGRNYLLPKKLAMEATAANKAVIEQMKASAVRRSAKEKAEAEQLVAQLDAVALVFERKVGDHDHLFGSVTSSDIAQQLEQQGFHIDRRKVQLEEPLKQTGEFLIPVKLHREVTAHVKVTVKGEETAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DXS_LEPBJ
Sequence: MQQESTLLDKIDYPADLRNIPLEKLPQVCKEVRNYIIDTLSGVGGHFASNLGVVELTVALHYVFDTPKDRLIWDVGHQTYPHKILTGRKDRLKTVRKFNGLSGFPKREESPYDLYNTGHAGTSISQALGEAAARDLTKGEDYSVVAIIGDASIATGMALEAMNHAGHLKKDMIVILNDNYMSISKNVGSISNYLNNIITSHFYNHWKRVFYTFLKWLPIVGPAAERFFKKVEKGFKDVLTPGGLFEDLGFGYIGPEDGHDVIRLVNMLAKVKKMKGPILLHLITQKGKGYDPAERDPIKYHGVTPFRKEDGAMDSGDTSKIAYSKIVGRMLSILTEANPKIAAITPAMIEGSGLKEYAEKYPDHLFDVGIAEQHSVAFAGAMTNGSIIPYMCIYSTFLTRAIDQLVQDVSLMNLPVRFVIDRAGCVGPDGETHQGLFDLGYLLGLPNMDVFVPSNGQDMIDSLRWMETYDKAPIAIRFPKANVDLKTLDFYKEVDLRPGTFRVLKRGTDLALLSIGSMIDEAKKATEILESAGFSVTLIDLIWLRPLGVEALNEELSNVRRFVIIDESYVDAGASGYLLNRILPENLSKYVKTFGFPPEPIHHGERKEIIQAYRLDGASIAESVADVLKKNLIKP
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: C12A2_MUSDO
Sequence: MLKTKQQIIALNRFRCWTSNLPGLQQQCRNQSTVTAASSEWEQAKPLSEMPTISPFQLLRHFLPGGKYTNLDTTQLMLAFRRDFGPIVYFKGSLGKPDVVMTNNPHDFEKALHNQGIWPMRPGMEYLSYHRQVHRKDIFQGVEGLLGSQGEAWGSFRSAVNPVLMQPKNVHLYFNKMSEVNKEFMERIRKIRDPQTLEVPDNFEEEINRWTLESVSVVALDKQLGLITKNRDDPTPKRLFKALTDFFEASGDLEFQPSIWKYIKTPTFKKAIRSLDEITDITKMYVDEAFERIEAENKNRNVEKPENEKSVLEKLVKIDKQIAMVMAMDMLMAGVDTTSSTFTGLLLCLAKNPEKQKKLREEIMQLLPQKDSEFNEAVFKNMPYLRACIKESLRVYPLTVGNARTQANDVVISGYRVPKGTLISMNSVTLIKDDAHYPRASEFLPERWLRASKENEKSAECPHALKASSPFVYLPFGFGSRSCIGRRIAEMELELGIARLIRNFHVEFNYPTDNAFKSLLISVPNIPLKFKFTDVDN
What are the official names of this protein?
Cytochrome P450 CYP12A2, CYPXIIA2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DPES_RUMCH
Sequence: MKHGIYYAYWEQEWEADYKYYIEKVAKLGFDILEIAASPLPFYSDIQINELKACAHGNGITLTVGHGPSAEQNLSSPDPDIRKNAKAFYTDLLKRLYKLDVHLIGGALYSYWPIDYTKTIDKKGDWERSVESVREVAKVAEACGVDFCLEVLNRFENYLINTAQEGVDFVKQVDHNNVKVMLDTFHMNIEEDSIGGAIRTAGSYLGHLHTGECNRKVPGRGRIPWVEIGEALADIGYNGSVVMEPFVRMGGTVGSNIKVWRDISNGADEKMLDREAQAALDFSRYVLECHKHS
What is the function of this protein?
Involved in the biosynthesis of D-psicose.  Catalyzes the reversible epimerization of D-fructose at the C3 position to yield D-psicose.  The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose.
What are the official names of this protein?
D-psicose 3-epimerase, DPEase.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: BIOH_IDILO
Sequence: MSISVTCCGTGTPIVVLHGWGMNSNIWQPVVPALSEHFQLYCVDLPGFGDSVWSSENDVSLESFIEQIMPALPPRFHLLGWSLGGLIATQIALTHSDRVMSLTTVASSPHFVESNDWAGIKPDILEQFQQQLDSNFKKTIERFLAIQAMGSEDAREQVKQVKQLIFTKPMPDQGVLKQSLTILQTADLRQQLPNIEVPFNRFYGRLDSLVPERAIDDISALAPESKAVVFTKSAHAPFISEPERFISELLKVVEN
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_YERPE
Sequence: MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLRKSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAWHERRAERGVRLVGLHVTLLDPQLERQLLLDWG
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIP30_MOUSE
Sequence: MDGEDDSNLVIKKRFVSEAELDERRKRRQEEWEKVRKPEDPKECPEEAYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEKQRREEELEELKEYRSNLNKVGISAENKEVEKKLAVKPIETKNKFSQAKLLAGAVKHKSSESGNSVKRLKPDPDPDDKAQEAPSCMSLGSSSLSGPPSIHCPSAAVCIGILPGLGAYSGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP
What is the function of this protein?
Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity.  Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome.  Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus.
What are the official names of this protein?
PSME3-interacting protein, NEFA-interacting nuclear protein NIP30, PA28G-interacting protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSX_BACAC
Sequence: MKIAIDAMGGDHAPKAVVLGAMKAIKEYSDLHITLVGKEEEIRQYLTSEERITILHTDEKIESTDEPVRAVRRKKQASMVLAAQQVKDGVADACISAGSTGALMAAGLFVVGRMEGIERPALSPTMPTVDGEGFVMLDVGANVDAKPIHLYQYAVMGSVYAEKVRGIKNPRVGLLNVGTEGGKGNELSKQVFAMLKDAPINFVGNVESRDLLQGVADVVVCDGFTGNVALKSLEGTALALFSMLKEQLMSSFTSKLAAAVLKPKLMVLKDKMDYSEYGGAALFGLKAPVIKAHGSSNDQSIFSAIRQTREMVAKEVIPTISSVMEKEPLQ
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PRO_MMTVB
Sequence: MGVSGSKGQKLFVSVLQRLLSERGLHVKESSAIEFYQFLIKVSPWFPEEGGLNLQDWKRVGREMKRYAAEHGTDSIPKQAYPIWLQLREILTEQSDLVLLSAEAKSVTEEELEEGLTGLLSTSSQEKTYGTRGTAYAEIDTEVDKLSEHIYDEPYEEKEKADKNEEKDHVRKIKKVVQRKENSEGKRKEKDSKAFLATDWNDDDLSPEDWDDLEEQAAHYHDDDELILPVKRKVVKKKPQALRRKPLPPVGFAGAMAEAREKGDLTFTFPVVFMGESDEDDTPVWEPLPLKTLKELQSAVRTMGPSAPYTLQVVDMVASQWLTPSDWHQTARATLSPGDYVLWRTEYEEKSKEMVQKAAGKRKGKVSLDMLLGTGQFLSPSSQIKLSKDVLKDVTTNAVLAWRAIPPPGVKKTVLAGLKQGNEESYETFISRLEEAVYRMMPRGEGSDILIKQLAWENANSLCQDLIRPIRKTGTIQDYIRACLDASPAVVQGMAYAAAMRGQKYSTFVKQTYGGGKGGQGAEGPVCFSCGKTGHIRKDCKDEKGSKRAPPGLCPRCKKGYHWKSECKSKFDKDGNPLPPLETNAENSKNLVKGQSPSPAQKGDGVKGSGLNPEAPPFTIHDLPRGTPGSAGLDLSSQKDLILSLEDGVSLVPTLVKGTLPEGTTGLIIGRSSNYKKGLEVLPGVIDSDFQGEIKVMVKAAKNAVIIHKGERIAQLLLLPYLKLPNPVIKEERGSEGFGSTSHVHWVQEISDSRPMLHIYLNGRRFLGLLDTGADKTCIAGRDWPANWPIHQTESSLQGLGMACGVARSSQPLRWQHEDKSGIIHPFVIPTLPFTLWGRDIMKDIKVRLMTDSPDDSQDL
What is the function of this protein?
The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell.
What are the official names of this protein?
Gag-Pro polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p10]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein-dUTPase]: Virion.
Protein: CLPP_LACLA
Sequence: MGYLVPTVIEQSSRGERAYDIYSRLLKDRIIMLTGPVEDGMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGTGQGTQQTDMAIVAEQLLKTRKRLEQILADNSNRSLEQIHKDAERDHWMDAKETLEYGFIDEIMENNSLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_BURP6
Sequence: MQSAIKSVEYDRPLAAGAACGVGEAWAKVPDALVPDERDALKARIKALLVREKAVLVAHYYVDADLQALADETGGCVADSLEMARFGRDHDAHTLVVAGVRFMGETAKILSPGKRVLMPDLDATCSLDLGCPIDEFSQFCDAHPERTVVVYANTSAAVKARADWMVTSSIGLEIVADLHARGEKIIWAPDRHLGGYIQKKTGADMLMWQGSCLVHDEFKGIELDLLRHEYPDAKILVHPESPEGVVALADVVGSTTQLIDAAVKLDAQRFIVATDLGILHKMRLAAPGKTFIEAPTAGNSATCKSCAHCPWMAMNALSNLADVLERGHNEIFVEAAIAQRARMPIDRMLDFAARHKQRVQASGDLQRDQALFANVGAA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECG_SYNY3
Sequence: MQCSLVEVSVSVDWPRLQKALTVEVERGFQNLQGKQHRFGDFLCLSFGSPPPPGSSPGDRQKWREFAQRFAQYDQLEEAERKSLVASTRRFLHQLRRSLESPPRDSVPKKDLLAQVNRPQVSEPRYPKSGQIELHTPLATVVSQSQHQTKLLKNLGLATVEDLLFYFPRDYLDYAQQVTIAELTAGETVTIVGRVVNCTCFTSPKNQNLNILQIQLRDQTGRIKLSRFYAGKRFAHRGWQEKIKKLYPPQAVVAASGLVKSSKFGLTLDNPEIEVLDRHSPSIDSFKVGRVLPVYPLTEGITADFLRKLVLACQTAIAKLSDPLPQEIREKYELIDLQTAIAQIHFPENTEKLSLARRRLVFDEFFYLQLGFLQRRYEQKQQQQSAIFTPHGELLEKFSDLLPFRLTQAQQRVVNEILQDLNKPSPMNRLVQGDVGSGKTVVGVFAILAALQGGYQAALMAPTEVLAEQHYQKLVSWFNLLYLPVELLTGSTKTAKRREIHAQLSTGQLPLLVGTHALIQETVNFQRLGLVVIDEQHRFGVQQRAKLLAKGNAPHVLSMTATPIPRTLALTLHGDLEVSQIDELPPGRQPIHTSVITAKERPQMYELIRREVAQGRQVYIIFPAIEESEKLDIKAAVEEHKYLTEKIFPNFNIGLLHGRLKSAEKEAALTAFREKQTEIIVSTTVIEVGVDVPNATVMVIENAERFGLSQLHQLRGRVGRGSHQSYCLLVTNSKSNDARQRLGVMEQSQDGFFIAEMDLRLRGPGEFLGTKQSGLPDFALASLVEDQEVLLLAREAAETMMVEDPNLEAHPDLKIKLVQRYEKLLGGEILT
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: TBB7_GOSHI
Sequence: MREILHVQAGQCGNQIGGKFWEVVSDEHGIDPKGNYVGTSRVQLERVNVYYNEASGGRYVPRAVLMDLEPGTMDSLRTGPHGQLFRPDNFIFGQNGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCACLQGFQICHSLGGGTGSGMGTLLISKIKEEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENGDECMVLDNEALYDICFRTLKLTNPSFGDLNRLISTTMSGATCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSSSSQQYRALTIPELTQQMWDARNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPTGLTMSSTFMGNSTSIQEMFRRVSEQFTVMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAVADDNDEDYEDEAMEN
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-7 chain, Beta-7-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CASP6_RAT
Sequence: MTETDGFYRSREVLDPAEQYKMDHKRRGTALIFNHERFFWHLALPERRGTNADRDNPTRRFSELGFEVKCFNDLRAEELLLKIHEVSTSSHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPLVPLDVVDHQTDKLDDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLSEMLARHGSSLEFTELLTLVNRKVSQRRVDFCKDPGAIGKKQVPCFASMLTKKLHFCPKPSK
What is the function of this protein?
Cysteine protease that plays essential roles in programmed cell death, axonal degeneration, development and innate immunity (By similarity).  Acts as a non-canonical executioner caspase during apoptosis: localizes in the nucleus and cleaves the nuclear structural protein NUMA1 and lamin A/LMNA thereby inducing nuclear shrinkage and fragmentation.  Lamin-A/LMNA cleavage is required for chromatin condensation and nuclear disassembly during apoptotic execution (By similarity).  Acts as a regulator of liver damage by promoting hepatocyte apoptosis: in absence of phosphorylation by AMP-activated protein kinase (AMPK), catalyzes cleavage of BID, leading to cytochrome c release, thereby participating in nonalcoholic steatohepatitis.  Cleaves PARK7/DJ-1 in cells undergoing apoptosis (By similarity).  Involved in intrinsic apoptosis by mediating cleavage of RIPK1.  Furthermore, cleaves many transcription factors such as NF-kappa-B and cAMP response element-binding protein/CREBBP (By similarity).  Cleaves phospholipid scramblase proteins XKR4 and XKR9.  In addition to apoptosis, involved in different forms of programmed cell death.  Plays an essential role in defense against viruses by acting as a central mediator of the ZBP1-mediated pyroptosis, apoptosis, and necroptosis (PANoptosis), independently of its cysteine protease activity.  PANoptosis is a unique inflammatory programmed cell death, which provides a molecular scaffold that allows the interactions and activation of machinery required for inflammasome/pyroptosis, apoptosis and necroptosis.  Mechanistically, interacts with RIPK3 and enhances the interaction between RIPK3 and ZBP1, leading to ZBP1-mediated inflammasome activation and cell death.  Plays an essential role in axon degeneration during axon pruning which is the remodeling of axons during neurogenesis but not apoptosis.  Regulates B-cell programs both during early development and after antigen stimulation (By similarity).
What are the official names of this protein?
Caspase-6, CASP-6, Apoptotic protease Mch-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.