PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_MYCA1
Sequence: MAIIGPTGTGKSQLALDVAERLGPLGAEIVNADAMQLYRGMDIGTAKLPVDARRGIPHHQLDVLDVTQTATVARYQRAAAADIEAILAAGAVPIIVGGSMLYIQSLLDDWSFPATDPRVRARWERRLAEVGVGELHAELARRDPAAAAAILPTDARRTVRALEVIELTGRPFAASAPRIGAPRWDTVIIGLDCDTTVLDERLARRTDAMFEQGLVAEVTGLLGRGLRDGVTAARALGYAQVIAALDAGGGDEQLRQAREQTYAGTRRYVRRQRSWFRRDHRVRWLDAGACSPPRLVDAALGAWRHVS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL18_YERPB
Sequence: MDKKAARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEILVAASTVEKAINEQLKYAGNKDAAAAVGKTIAERALEKGITKVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HFQ_XANOM
Sequence: MAKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSNEGNQAEDDDVEQ
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: EX7S_TRIV2
Sequence: MVKRKNSDNSGTVAQGNYEAKVAEIEAIISRIESGELELETVFEQFANAVQYLRQCDTFLQQRQQQIDLLIETLNEQDGDQIPRVSNDGIEPKK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIL1_YEAST
Sequence: MSDSEEDLGVQLKGLKIARHLKESGEHTDEESNSSPEHDCGLSNQDDLTVMHTQAKEEVFKRREEDGTRTEDALHEGEAGKEGTGFPSSQSVCSPNEADSGIDRADKPILLDPFKSVHDTDPVPGTKSRSNSDSDSDSDDGGWQEMPAVSSFNIYNHRGELELTSKVRNSEQASETSPTVPPGKNCKSVNDSRFDYTKMAAEQQAQRSYRTNKKTDFLFDHKVLKKKINSSQTSVNLTSSPSTTSLNNEKNNDDDDDDSYDEYEDDVEPVNDLNRDSQLNITKNLLSDMEKFAYVGAINILANQMCTNLATLCLCIDIKSHKKLAHRLQFTQKDMAAWKTVVLSRLYDHLGISQEEIVMIEKLSLHKIQLEDLCKCLKTTQSIDNPWENDRDHEEDGIEETTERMSPNEQNGSVQASTPDPEQSATPETPKAKQSPLSSDVPGKVLDPENVKSQDKLNIDVAWTIICDLFLICLQSSTYDSRSRTLLINFAKVLNMTSLEICEFERRVTDSLDMEQSTEDQVWDEQDHMRNRRRSKRRKKMAYVALAMVGGSLVLGLSGGLLAPVIGGGIAAGLSTIGITGATSFLTGVGGTTVVAVSSTAIGANIGARGMSKRMGSVRTFEFRPLHNNRRVNLILTVSGWMVGNEDDVRLPFSTVDPVEGDLYSLYWEPEMLKSIGQTVSIVATEIFTTSLQQILGATVLTALISSIQWPMALSKLGYILDNPWNVSLDRAWSAGKILADTLIARNLGARPITLVGFSIGARVIFSCLIELCKKKALGLIENVYLFGTPAVMKKEQLVMARSVVSGRFVNGYSDKDWFLAYLFRAAAGGFSAVMGISTIENVEGIENINCTEFVDGHLNYRKSMPKLLKRIGIAVLSEEFVEIEEMMNPEEVKRKRKLINDVDAAQKKLSERKKHNSWVPKWLKPKKSKWKVMVEEAVEEGRDMQDLPENDVNNNENENPDEHEGIARQKRRDAALVDHGALMHELQLIKQAMHEDEIKNKACLPGEDKEVESSNDFLGESHYKPPSTPKINPPQSPNNFQLLSAGRTILPEDDDFDPRGKKKVEFSFPDDI
What is the function of this protein?
Probable lipase that recruits the AP-1-related (AP-1R) complex to membranes via interaction with APM2 (PubMed:26658609).  The AP-1R complex is an adapter protein complex that mediates of cargo protein SNC1 sorting in clathrin-coated vesicles (PubMed:26658609).
What are the official names of this protein?
Probable lipase MIL1, Medium adaptin-interacting ligand 1.
What is the protein family that this protein belongs to?
Belongs to the TMCO4 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi- pass membrane protein.
Protein: TMEDE_DROSI
Sequence: MRDQFISLALILCVLHSACGLYFHISETERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYANVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV
What is the function of this protein?
Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo.  Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected.  Involved in Golgi organization (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein eca.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: CORC_BUCBP
Sequence: MSDDNAQHSDKENKKGFFSILLSQIFHDEPKNKEELLTLIKYSEENELIDRETGHMLEGVIHITKQKIRDIMIPRPQMITLKLTYSLEQCLDVITKSLHSRFPVMSENENYVEGFLITKDLLPFIKNNTEMFCIKKILRPAIVVPESKHVNHMLKEFRLTKNHMAIVIDEFGVVSGLVTIEDILELIVGNIEDEYDETKKNICQLNQSTFIIKSLTSIKEFNETFNTNFNDEEVDTIGGLVMKKIGHLPIRGEYININQYKFKIHIANNRRIILLQVTIPKK
What is the function of this protein?
Plays a role in the transport of magnesium and cobalt ions.
What are the official names of this protein?
Magnesium and cobalt efflux protein CorC.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
Protein: ACKA_BUCBP
Sequence: MFNKLVLILNCGSSSLKFSVVSSDNYTTKLSGIVEFLNLSQIRFFWKIKKKEYVRVINKSKSYDYALNYILTKILKEESKIFNNIACVGHRVVHGGVNLNKSVLITQEIIKLITDACSFAPLHNPINLLGIKASHAVLPHLKEKNVAVFDTSFHSSIPKFAYLYAIPYKFYKKFGIRKYGAHGISCQYSVCRSSELLQIELTSLNIIICHLGGGASVSVVKNGVCVDTSMGLTPLEGLIMGTRSGDIDPSVIFFMNKQLNLSISTINNILINKSGLLGLSGVSSDFRNLESEYNSNIRIKLAIDMFCYRLSKYISGYMSVVKGKLHGIVFTGGIGENSSLVRSIVISKLAFLNFKLNSDINMLMKSGKEGFINIKNTFPILVIPANEELIIAKESFSEIN
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMAN1_RAT
Sequence: MAVSRRRGPQAGAQSFFCALLLSFSQFVGSDGMGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQGLDGPVFGSADMWNGVGIFFDSFDNDGKKNNPAIVVVGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTPEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVSQQELDTVVRTQLEILRQVNEMKNSMRETMRLVSGVQHPGSAGVYETTQHFMDIKEHLHIVKRDIDSLAQRSMSSNEKPKCPDLPAFPSCLSTVHFVIFIVVQTVLFIGYIMYRTQQEAAAKKFF
What is the function of this protein?
Mannose-specific lectin.  May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.  The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins (By similarity).
What are the official names of this protein?
Protein ERGIC-53, ER-Golgi intermediate compartment 53 kDa protein, Lectin mannose-binding 1, p58.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: IMP3_YEAST
Sequence: MVRKLKHHEQKLLKKVDFLEWKQDQGHRDTQVMRTYHIQNREDYHKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVTVSAICRRRLPVIMHRLKMAETIQDAVKFIEQGHVRVGPNLINDPAYLVTRNMEDYVTWVDNSKIKKTLLRYRNQIDDFDFS
What is the function of this protein?
Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing.
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein IMP3, U3 snoRNP protein IMP3, Interacting with MPP10 protein 3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: POMP_DICDI
Sequence: MQSIVKKDLDLPTLRNESSNVKGLSHPVESIQLDQGKTEIKLKNFAMKNVFGTHMVMNNEIEKQIYSQFKRLPTLQSSMVGLETILGLDEDFDFGDYLCDPATSEAPLPQLHTSMEHRLGMTSSKSIL
What is the function of this protein?
May function as molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes.  Degraded after completion of proteasome maturation (By similarity).
What are the official names of this protein?
Proteasome maturation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: EFTS_CHLPN
Sequence: MSDFSMETLKTLRQQTGVGLTKCKEALEACGGNLEEAVVYLRKLGLASAGKKEHRETKEGIIAAKTDANGTALIEVNVETDFVANNAVFREFVSNLLNDILKYKVDTVEALSQAASSQDPSLSVDELRAVTMQTVGENIRISRVAYFPKATNSTVGIYSHGNGKTVALTMLSGSSTADSLAKDIAMHVVAAQPQFLSKESVPAEAIAKEKEVIASQIQGKPQEVIEKIVTGKLNTFFQEACLLEQPFIKNADLSIQSLIDDFSKTSGSSVAIEQFILWKIGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_PSEP1
Sequence: MRIVFAGTPEFAAEHLKALLDSPYEIVAVYTQPDRPAGRGQKLMPSAVKALAVAHDIPVFQPQTLRNADAQAELAALKPDLMVVVAYGLILPQVVLDIPRLGCINSHASLLPRWRGAAPIQRAVEAGDAESGVTVMRMEAGLDTGPMLLKVVTPISAEDTGGTLHDRLAEMGPPAVVQAIAGLADGSLQGEIQDDALATYAHKLNKDEARIDWTRPAVELERLIRAFNPWPVCHSMLDGESVKVLAANLSTGQGAPGEILSASKDGLVVACGDQALSLTRLQLPGGKALSFSDLFNSRREKFAAGKVLGQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LEUC_LISMH
Sequence: MGKTLFDKLWNRHVIYGKEGEPQLLYVDLHLIHEVTSPQAFEGLRMENRPLRRPDKTFATMDHNVPTEDIFNIQDLVAKKQIEALQTNCEEFGVTLADMGSDRQGIVHMVGPETGLTQPGKVIVCGDSHTATHGAFGAIGFGIGSSEVEHVFATQTIWQQKPKSMGIEINGKLPKGVYAKDIILHLIATYGVAFGTGYAVEYYGETIRNMSMEERMTICNMAIEGGAKMGMMAPDETTFEYVRGREYAPADMEKAIRDWKTLQTDPDAEYDLHIEMDASILEPYVTWGTNPEMGVPFSKAFPEIKDMNYERAYEYMGLKPGQTAEEIELGYVFIGSCTNARLSDLEEAARIVKGNKVKNNIRALVVPGSRQVRNAAESIGLDKIFIEAGFEWREPGCSMCLGMNPDQVPDGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAINGHFIDIRKEAIISGGN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PSBB_SYNY3
Sequence: MGLPWYRVHTVVLNDPGRLISVHLMHTALVAGWAGSMALYELAIFDSSDAVLNPMWRQGMFVLPFMARLGVTSSWNGWSVTGETGLDPGFWSFEGVAAAHIVLSGLLFLAAVWHWVFWDLELFVDPRTGESALDLPKMFGIHLFLSGLLCFGFGAFHLTGVWGPGMWVSDPYGLTGHVQPVAPEWGPAGFNPFNPGGVVAHHIAAGIVGIIAGLFHLTVRPPERLYKALRMGNIETVLSSSIAAVFFAAFVVAGTMWYGNATTPIELFGPTRYQWDKGYFQEEIQRRVDSQLAEGASLSEAWSTIPEKLAFYDYVGNSPAKGGLFRTGAMNSGDGIAQEWIGHPIFKDKEGRELEVRRMPNFFETFPVIMTDADGVVRADIPFRRSESKFSVEQTGVTVSFYGGALDGQTFSNPSDVKKFARKAQLGEGFDFDTETFNSDGVFRTSPRGWFTFGHAVFALLFFFGHIWHGSRTLFRDVFAGVDPGLEEQVEFGVFAKVGDLSTRKEA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RPOZ_MICAN
Sequence: MSKRFKFDSSEMIYLTDKLMNAASNRYSIVVQVARRAKRVRYDTVENIDDPMIKPVQRALMEMTDELTEPELLRD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PNP_CUPNH
Sequence: MSMFNKIVKEFQWGQHTVRMETGEIARQAGGAVLVDVEDTVVLATVVAAKNPKPGQDFFPLTVDYIEKTYAAGKIPGGFFKREGRPSENETLTSRLIDRPLRPLFPEGFYNDVQVVIHVVSLNPEVPADIPALIGASAALAVSGIPFNGPVGAARVGYKDGQYLLNPTRSQLATSDLDLVVAGTERAVLMVESEANQLSEDVMLGAVVYGHEQMQIAINAIHELVREGGKPEWDWAPAAKNEPLIAKVTEVALPLLQEAYQLRQKSARSQKLKEVNANVAAALAAAGVEADKVEVGNIMFDLEAKIVRGQVLAGEPRIDGRDTRTVRPIEIRSSVLPRAHGSALFTRGETQALVVATLGTKSDEQIIDALAGEYRDRFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALIPVLPKDDEFAYTIRLVSEITESNGSSSMASVCGGCLALMDAGVPVKAHVAGVAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTDNGITALQMDIKVQGITKEIMQVALAQAREGRLHILHKMQEAMGHARTELSAHAPRMITMKIHPDKIREVIGKGGSTIQALTKETGTTIDIQEDGTITIASTSTDGMAEAKRRIEGITAEAEVGKIYAGTVLKLLDFGAIVNILPGKDGLLHISEIVNERVKDIKDWLKEGQQVRVKLIQADEKGRLRLSLKAALTEEGGSISPINAGEAAAPAAPAEGSEQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_DINSH
Sequence: MARPKIALIGAGQIGGTLAHLVALKELGDVVLFDIADGTPQGKALDIAESGPVERFDASLKGTTDYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIAANAPDAFVICITNPLDAMVWALQQFSGLPKEKVVGMAGVLDSARFRHFLAEEFNVSMKDVTAFVLGGHGDTMVPLTRYSTVAGIPLPDLVEMGWTSQEKLDAIVQRTRDGGAEIVGLLKTGSAFYAPAASAVEMAEAYLKDQKRLLPCAAYCDGEFGLNDMYVGVPTIIGAGGIEKVVDIKLGKDEQAMFDNSVNAVKGLMEACKGIDDSLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: MREG_XENTR
Sequence: MCLKDWLCAFCCLRLGCLEYPKNEKQPLVSGNNNQYKTYAVIDDDERNLWSSPHDLSHTEAVDDRMLQSWIQTRNQLEKDSEEWQKLNYEIYTLRQARREVRARWRRILEDLGFQKEAETLLSVTKQSTISNPKNMKRAMELLVKLSDNTTIFPAGWDLPVRYLYIMDRLICLDAVDDFLNIAQKKYPKTKMDISQ
What is the function of this protein?
Probably functions as cargo-recognition protein that couples cytoplasmic vesicles to the transport machinery.  Contributes to retrograde melanosome transport from the cell periphery to the center.  Overexpression causes accumulation of late endosomes and/or lysosomes at the microtubule organising center (MTOC) at the center of the cell.  Probably binds cholesterol and requires the presence of cholesterol in membranes to function in microtubule-mediated retrograde organelle transport.  Binds phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate and phosphatidylinositol 3,5-bisphosphate.
What are the official names of this protein?
Melanoregulin.
What is the protein family that this protein belongs to?
Belongs to the melanoregulin family.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein. Melanosome membrane; Lipid-anchor. Lysosome membrane; Lipid-anchor. Cytoplasmic vesicle membrane.
Protein: RNH2_RUEPO
Sequence: MARNGPPGRGRSSLPFCLSRGVNCGQSRGMTQPDYQLEAALAAQGHIRIAGVDEVGRGPLAGPVVAAAVVLDPGAIPEGLNDSKKLTAARRERLYDILHANAQVSIAEASVEEIDALNILRASHLAMERAVAALNPAPDFLLIDGNLIPAGLSCPAEAVIKGDGRSVSIAAASIVAKTWRDRLMVDLAQQHPGYGWERNAGYPTKEHRSALQNLGVTPHHRRSFKTVHKILYQE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y585_METJA
Sequence: MKKLAFLILLIVFSNLSLVNAIDDNISNYSKEINELTVKLKELESKNPNDERIEEYKEKLKQLIEKQHELKSQNLKYNETLAYIQSEEYWKMQEEIWEYNNKVMKWFIAISILILGIILATLWILRKDKFLLFLAIFGLIVPFLQFKIPNWLFNILALPLFVYIKFIVPECAEGSFYYSPLITIPISMYGWILIGLAVKFIIKKY
What are the official names of this protein?
Uncharacterized protein MJ0585.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PIP_MYCGE
Sequence: MNTKLNVKGYLNVGDNHQLYYWTQGNPNGKPVLYIHGGPGSGTDEGCLKYFDLETTWIILLDQRGCGKSKTNDIFYENNTDKLVSDFEILRQKLNIKNWTLFGGSWGSALALVYAIKHPQVVDKIFLRALFLAREKDWSEALMGLGKMFYPYEHQRFMDSIPKAYQNSYEQIVNYCYDQFQNGDESTKEKLAKAWVDWESTLLSPINKIHSTATDFKLVEKLALLECHYAVNKSFLDENFILDNISVLKNKSIYLAHGRFDLICPLYQPLALKQAFPELQLYVTNNAGHSGSDANNLATIKHLLKTYL
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Putative proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_DINSH
Sequence: MMDGTNFDDALTGEQKIRNFNINFGPQHPAAHGVLRLVLELDGEIVERCDPHIGLLHRGTEKLMESRTYLQNLPYFDRLDYVAPMNQEHAWCLAIEKLTGTVVPRRGSLIRVLYCEIGRILNHLLNITTQAMDVGALTPPLWGFEEREKLMVFYERACGARLHAAYFRPGGVHQDLPPDLLDDIEAWSHEFPSVMDDIDGLLTENRIFKQRNCDIGVVTEEEILEWGYSGVMVRGSGLAWDLRRAQPYECYDEFDFQIPVGKNGDCYDRYLVRMQEMRESLKIIQQAIVKLRETKGDVLARGKLTPPSRADMKTSMEALIHHFKLYTEGFHVPAGEVYAAVEAPKGEFGVFLKSDGTNRPYRAKIRAPGYLHLQSMDHVAKGHQLADVAAIIGTMDVVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FZD9_RAT
Sequence: MAVPPLLRGALLLWQLLATGGAALEIGRFDPERGRGPAPCQAMEIPMCRGIGYNLTRMPNLLGHTSQGEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSGGTCDNPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVASMDPAALTGFVLVPLSCYLVLGTSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAAAVPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKMAAGRARAKACRTPGGYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL
What is the function of this protein?
Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:12138115).  Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (By similarity).  May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (By similarity).  During hippocampal development, regulates neuroblast proliferation and apoptotic cell death.  Controls bone formation through non canonical Wnt signaling mediated via ISG15.  Positively regulates bone regeneration through non canonical Wnt signaling (By similarity).
What are the official names of this protein?
Frizzled-9, Frizzled-like protein 9, rFz9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Relocalizes DVL1 to the cell membrane leading to phosphorylation of DVL1 and AXIN1 relocalization to the cell membrane.
Protein: CAPP_SHIF8
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRHVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ISPDF_RHOPA
Sequence: MTNSPRTAAIIVAAGRGLRAGAGGPKQYRSLAGRPVIARAMEPFCTHPGVMAVQPVTNPDDTEMFNAAVAGLNFRPAVGGGATRQASVRAGLEALAELKPDIVLIHDAARCFVTPELISRAITAAGATGAALPVVPVTDTIKQVDSSGAVDATPDRASLRIAQTPQAFRFDVILDAHRRAASGGRDDFTDDAAIAEWAGLTVSTFEGDANNMKMTTPEDFAREESRLMAALGDIRTGTGYDVHAFGEGDHVWLCGLKVPHTRGFLAHSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAIDRVTARGGRVANLEVTMICERPKIGPLRDAMRQRIAEITGVPVSRVAVKATTSEKLGFTGREEGIAATASATIRLPWGADGLAG
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.