PharMolix/UniProtQA huggingface dataset:
Protein: PCKA_SHESM
Sequence: MADGLNRVHYNPSTAQLVEFALLRGEGELTANGALVAKTGTRTGRSPGDRFIVKEPSSAADIEWGPVNQAFEPGAFEGLWARVEAFLADKELFVSDLEVGADPEHYQPVRVTTQYAWHQLFARNLFIIPEEFNRQDKPVWQIINAPDFVCVPERDGTNSDAAVILNFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAQGVLPMHCSANVGKDGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVVMDEHRVPNYKDSSLTENTRAAYPLEHIAQRKEDNRGAEPHAVVFLTCDVSGVLPPVSILSKEQAAYHFLSGYTAKVGSTEIGSTSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGIGKRFDIPTTRAIVDAIVSGELKNAETVHLDTLNLAVPVAVPGVDTNLLNPVNTWSDKALYAEYAQKLAEAFTKNFAKYQVSDAIRNAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_PSEA7
Sequence: MRTSQYLLSTLKETPADAVVISHQLLLRAGMIRRLASGLYTWLPMGLRVLRKVETVVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKDRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHLNQESLQATYDGMYQAYSKIFTRLGLDFRPVQADNGSIGGSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVPRESARGAASEDMRLVDTPDTKTIAALVDGFGLPIEKTIKTLVVHGAEEGTLVALIVRGDHELNEIKAANQPLVASPLVFASEAEIRAAIGAGPGSLGPVNLPIACIVDRSVALMSDFAAGANIEDKHYFGVNWERDLPLPEVADLRNVVEGDPSPDGKGTLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGVSRVVAAAIEQNHDERGILWPSALAPFQIALVPLKYETESVRQATDRLYAELTAAGFEVLLDDRDKKTSPGVKFADMELLGIPHRIVVSDRGLNEGVLEYKGRRDSESQNLPIGELMSFITEKLSR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOC2_ILYPC
Sequence: MIDKKKVNRNFSKGAKTYDEYALIQRHMADKLGIFIEDSEEVFNILEIGCGTGIFSEKILNKFPNSNIDFLDISHDMIKNVKDKIGSKENLNFIVEDIEKYQPQKKYDLIFSNATFQWIQNKKGLFDHLDSFLKPGGLILFSTFGKDTYFELRESLKSIDPDLEYSQNFISLEDLKKVLDDKYKILAAEEERIKENYHCVMDFLKMIKGIGANSALSNSKPFTRDKFNRLEDEYRKNYCSGDSIEVTNHLIYMILGKNY
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase 2, Malonyl-ACP O-methyltransferase 2, Biotin synthesis protein BioC 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RILP_MOUSE
Sequence: MEPRRAAPRLPSQASSSVGAGSAAELVYHLAGALGTELQGLARRFGPDAAAGLVPLVVRALELLEKAAVGPAPDSLQVSAQQAEVELRRLREENQRLRQELGSGPQEERALLRQLKEVTDRQRDELRAHNRDLQRRSQETEALQEQLQRLLLINSELRHKLAAVQTQLRAAQDRERERQIAQDGSSQLAKEQSLEPDAATSDDPVDTQKQPGNLPEAVQCGFSREELKQILQERNELKANVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVKKQRRKIKAKMLGTPEEAESSEDEDGSWLLLSNDKEDVPLVPESRIQNFFGLWYRGETEAPEAETSNPASSSLQKGEETPQQPHLQPVNSPPAPNS
What is the function of this protein?
Rab effector playing a role in late endocytic transport to degradative compartments.  Involved in the regulation of lysosomal morphology and distribution.  Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments.  Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
What are the official names of this protein?
Rab-interacting lysosomal protein.
What are the subcellular locations of this protein?
Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
Protein: CTAA_RICM5
Sequence: MQKSLITKWLCISCIMVIATIVIGGITRLTGSGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGITLSQFKFIYLLEFIHRLLGRITALIYIVPLIYFYFKDVIKNRDMLPYIIALWLFCVQGFMGWYMVKSGLLNSPYVSHCRLAFHLIIAVIIYHILFYQLIKNRCDILLIPSQTDLKLPLIFSGIAITVVYVQIFLGALVAGLDAGLIYNSFPLMDYSFIPMEIKDNFFDLKNWYDPVFIQFIHRLGGYSVFLVVVVLIICLLKIEHPKLNKIAYFLMIALLMQVSTGIITLLYSVPIIIASIHQLFAVILLSIIIWCCFLIKSS
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCB_ENT38
Sequence: MDYFTLFGLPAQYSIDLPALTIRFQDLQRQFHPDKFASGTPAEQLAAVSQSATINQAWQTLRNPLARAEYLLSLHGFDLTSEQHTVRDTAFLMEQLELREELDEIDQAKDEARLESFIKRVKGMFDSRHQQMVEQLNNETWDVAADSVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: LIPC_MYCTU
Sequence: MNQRRAAGSTGVAYIRWLLRARPADYMLALSVAGGSLPVVGKHLKPLGGVTAIGVWGARHASDFLSATAKDLLTPGINEVRRRDRASTQEVSVAALRGIVSPDDLAVEWPAPERTPPVCGALRHRRYVHRRRVLYGDDPAQLLDVWRRKDMPTKPAPVLIFVPGGAWVHGSRAIQGYAVLSRLAAQGWVCLSIDYRVAPHHRWPRHILDVKTAIAWARANVDKFGGDRNFIAVAGCSAGGHLSALAGLTANDPQYQAELPEGSDTSVDAVVGIYGRYDWEDRSTPERARFVDFLERVVVQRTIDRHPEVFRDASPIQRVTRNAPPFLVIHGSRDCVIPVEQARSFVERLRAVSRSQVGYLELPGAGHGFDLLDGARTGPTAHAIALFLNQVHRSRAQFAKEVI
What is the function of this protein?
Esterase that can hydrolyze short-chain esters with the carbon chain containing 2 to 10 carbon atoms.  Does not have lipase activity.  Is highly immunogenic and elicits strong humoral immune responses in both HIV-negative (HIV-) and HIV-positive (HIV+) tuberculosis (TB) patients.  Also elicits pro-inflammatory cytokine and chemokine responses from macrophages and pulmonary epithelial cells (PubMed:22038913).  May participate in the progression of active tuberculosis both by contributing to the utilization of lipid substrates for bacterial growth and replication, and by modulating immune responses (PubMed:22038913).
What are the official names of this protein?
Esterase LipC.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell surface. Secreted, cell wall. Secreted, capsule. Note=Cell surface protein that is present in both the cell wall and the capsule.
Protein: PROQ_ECO24
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAH1_HUMAN
Sequence: MALCEAAGCGSALLWPRLLLFGDSITQFSFQQGGWGASLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGNSLDIPVAVTIFFGANDSALKDENPKQHIPLEEYAANLKSMVQYLKSVDIPENRVILITPTPLCETAWEEQCIIQGCKLNRLNSVVGEYANACLQVAQDCGTDVLDLWTLMQDSQDFSSYLSDGLHLSPKGNEFLFSHLWPLIEKKVSSLPLLLPYWRDVAEAKPELSLLGDGDH
What is the function of this protein?
Probable lipase.
What are the official names of this protein?
Isoamyl acetate-hydrolyzing esterase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
Protein: RIMP_GEMAT
Sequence: MGEAIEPIVTQELAGLGFDLVELRRGGSRARPVLEIRIDRRDEEKVTIDDCARVSRALEARLEAAALVGEQYVLEVSSPGADRPLRHAADWRRFVGRRATVTSGLLAGGKQEVEIVAVTGEGGAEVALVRDPKGREVSVPLREVSQARLAFNWKR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI1_AQUAE
Sequence: MGVKKLSRKDYLNILESILFIDFLKGLSVTLKNLLRRPITTEYPKEKLTPPKRFRGAHGHYVWDGTEPDSLKAIEKFMSYEKAKSRCVACYMCQTACPMPTLFRIEAVQLPNGKKKVVRFDMNLLNCLFCGLCVDACPVGCLTMTDIFELANYSRRNEVLRMEDLEKFAIDFKQRRGNEPDRIWPNDEEREKLWGKIEWSG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLYA2_MYCBO
Sequence: MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVMQAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATANAATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVAEAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPVPHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLGHVIAAKATAFKMAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDGQQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAAALTATNDDQLGPLRAQVQRLAARYPLYPELHRT
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_RALSO
Sequence: MDTQAVRAYLLDLQDRITTAVGTLDGGTFVTDTWDKPPTERLRGSGRTCILENGAVLERGGVGFSHVMGDTLPPSATANRPELAGRGFEAMGVSLVFHPRNPYAPTVHMNVRCFVAQRPDAEPVWWFGGGMDLTPYYGFAEDAAHFHRTCKQALEPFGEELYPRFKQWCDDYFYLKHRKEARGVGGIFFDDFAELGFERSFEMMRAVGDALLPAWLPIAEQRHATPYGERERAFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSMPPVANWRYDWQPEPGSPEAALYTDFLPARDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PECAS
Sequence: MKNENLQQKNQTVSSPIVVALDYASQDAALSFVDRIDPQDCRLKVGKEMFTLFGPQFVQTLQQRGFDVFLDLKFHDIPNTVAHAVAAAADLGVWMVNVHASGGSRMMAAAKDALVPFGKDAPLLIAVTVLTSMDEEDLRGLGITVSPAEQAERLAVLTHNSGLDGVVCSAHEAQRLKQVCGQAFKLITPGIRPAGSDVGDQRRIMTPIQAQQAGVDYMVIGRPITQSSDPAQTLCDIRASLLNGIAS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: UVRC_MYCS2
Sequence: MPDPATYRPAPGSIPVEPGVYRFRDPHGRVIYVGKAKSLRSRLTSYFADITSLAPRTRQMVMTAGSVEWTVVTTEVEALQLEYNWIKEFDPRFNVRYRDDKSYPVLAVTLNEEYPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHKQIDRPCLLGYIDKCSAPCVGRVSAEQHRQIVLDFCDFLGGKTDRLAKDMEQQMTAAAEQLDFERAARLRDDISALKRALEKQAVVFGDGTDADVVAFADDDLEAAVQVFHVRGGRVRGQRGWIVEKSSEPAATGDADLGQSGQEQLVEQFLTQFYGEQAELGSASDTGGDEATNPVPRQVLVPVLPPNADELATWLSGLRGSRVSLRVPVRGDKRALAETVQRNAQEALAQHKLKRAGDFNARSEALQSIQEALGLADAPLRIECVDISHVQGTDVVASLVVFEDGLPRKSDYRHYAIREAAGDGRSDDVASIAEVTRRRFLRHTSDSQPDPSAEQRPRRFAYPPNLFVVDGGAPQVNAAAAVLEDLGVDDVAVIGLAKRLEEVWVPSEPDPVILPRNSEGLYLLQRVRDEAHRFAISYHRSKRSKRMTASALDSVRGLGEHRRKALVAHFGSVARLKEATVDEITAVPGIGVATARAVQEALGVAPQNGTAPDPAPGTGDPQTPADPHSAATAADIEDDRHATGATGPQMNGSEQQVDRV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUH_HALRO
Sequence: MYHLNVTPDKQTSPHGCLVVSETDQQRSHVKERVNGTPNQNGGTSTSSKPRSVFENRPPQRLTREAMSKYLRERNDQTLIILHAKVAQKSYGNEKRFLCPPPCLYLMESGWKQKQQILEEADQAPEAGQVHAFIGIGSSDQEMQQLNLDGKNFCTAKTLYISDTDKRKHFMLCVKMFFGSGLEVGAFNSRRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVENGNFHASSIQWGSFAIHLLDDDESESEEFTVRDGYIHYGQTVKLVCSTTGMALPRLIIRKVDKQTAILNADDPVSQLHKCAFYLKDSERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFCDGMGPTSKPVTPVPVVHSLQLNGGGDVAMLEVNGENFSPQLKVWFGEVEADTMYRCEEGLLCVVPDISEFREGWTWVKQSVQVPINLVRHDGIIYPTNLTFTFTPEPGPRPTLARLLYISSTPRDRIMPDRVPGRGVLIRPTWTTT
What is the function of this protein?
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations.  Acts as a transcriptional repressor when it is not associated with Notch proteins.  When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity).
What are the official names of this protein?
Suppressor of hairless homolog, RBP-Jkappa.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_FRATT
Sequence: MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLCYAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STXA_SHIDY
Sequence: MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDSVRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS
What is the function of this protein?
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits.  After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
What are the official names of this protein?
Shiga toxin subunit A.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family.
Protein: RPOB_ARTS2
Sequence: MVASSTSNVNNATAINADSTDGATRRLSFAKIHEPLDVPNLLALQTDSFDWLVGNERWQARVAKAVEEGDLSVATSSGLSDIFEEISPIEDFQGTMSLSFSDPEFADPKYTMAECKDRDATYSAPLYVKAEFMNNNTGEIKQQTVFMGDFPLMTEKGTFVVNGTERVVVSQLVRSPGAYFERTADKTSDKDIFTAKIIPSRGAWFELEIDKRDQVGVRLDRKRKQSVTVLLKALGWTEGQILEEFGQYDSMRATLEKDATETREDALLDIYRKLRPGEPPTVEAAQSLLDNLYFNSKRYDLAKVGRYKINRKLGIDRSLGDKEASVLHVEDIVAMIKFLVALHAGEKTLTGKRDGQDHELRVEIDDIDHFGNRRIRAVGELIENQVRTGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRDRAGMEVRDVHPSHYGRMCPIETPEGPNIGLIGSLASYGRINPFGFIETPYRLVSEGVVSDEVQYLTADDEAEVLIAQANAPLDENKKFAEETVLVRARGGGGEPVLVPAADVEFMDVSPRQMVSVATALIPFLEHDDANRALMGANMQRQAVPLVRSEAPFVGTGMERAAAVDAGDVVIAKKAGVVTEVSAELVIMLNDDGTETNYRINKFARSNQGNCYNHRVLVSEGQRLEVGGIIADGPATDQGELALGKNLLVAFMSWEGHNFEDAIILSQRIVAEDVLSSIHIEEHEIDARDTKLGAEEITRDIPNVSEEVLAGLDERGIIHIGAEVEAGDILVGKVTPKGETELTPEERLLRAIFGEKSREVRDTSLKVPHGESGTVIGVRVFDRDNDDELPPGVNQLVRVYVAAKRKITDGDKLAGRHGNKGVISKILPIEDMPFLADGTPVDIVLNPLGVPGRMNVGQVLETHLGWVAKTGWKIEGEPEWVKQLPNLPRESGSTTVATPVFDGAREEEITGLLDSTNVTRDGDRLINSSGKTRLFDGRSGEPFPDPISVGYMYILKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQELLTIKSDDIHGRVKVYEAIVKGENIPEPGVPESFKVLIKEMQSLCLNVEVLSTDGTTIEMRDSDDAVFTAAEELGIDLSRAEPSSVEEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SYM_ECOSE
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHO_SALG2
Sequence: MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DAPD_NEIMA
Sequence: MSLQNIIETAFENRADITPTTVTPEVKEAVLETIRQLDSGKLRVAERLGVGEWKVNEWAKKAVLLSFRIQDNEVLNDGVNKYFDKVPTKFADWSEDEFKNAGFRAVPGAVARRGSFVAKNVVLMPSYVNIGAYVDEGAMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQASPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIFDRTTGEIYQGRVPAGSVVVSGSMPSKDGSHSLYCAVIVKRVDAQTRAKTSVNELLRGI
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIN9_ORYSJ
Sequence: MITGSEVYQVVEAMAPLYTAAALGYGSVRWLKAFSNEQCAGINHFVALYAVPVLIFDMVSTNNVYKMNGRLIAADTLQKAVLLLGLMAWALWERSRARGAGAKAKAAVSSPLQWVITCFSVASLPNTIIMGVPLLNGMYGPVSKDLMKQIVVMQFCIWYNVIIFLYEYMAARRSASAPPPASSEGSAKISPSSPVKAAAAAADTNGNAVAADRPQEVAVNIEITEMAASTARDGVSGETTAAAKEVSSGEVAPVEEEEASAPAPSMKHVIWMAVKKLLQIPNTYASFLGLIWSLIAFKCGFSMPKIVEDSLFTIRTTAVGLSMFSSGTFIARQSRFVPCGYKIASFSMVIKFLIGPVVMLFASLVIGMHGTLLHIAVVQAALPLAVTSFVYAEEYKVHADIMSTGVILGIFISLPVTIVYYILLGL
What is the function of this protein?
May act as a component of the auxin efflux carrier.
What are the official names of this protein?
Probable auxin efflux carrier component 9, OsPIN9.
What is the protein family that this protein belongs to?
Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL31B_STRPJ
Sequence: MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RS11_CHESB
Sequence: MAKEAARVRRRERKNISSGVAHVNSTFNNTMITITDAQGNAIAWSSAGAQGFKGSRKSTPFAAQVAAEDCARKAQEHGMRTLEVEVSGPGSGRESALRALQAAGFTITSIRDVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y1553_SACEN
Sequence: MSPAAARAAFRAGLRVPTSGYSAGWTQANLIALPRDYAYDFLLFAQRNPKSCPVLDVTEPGETSASIFAGDLRTDLPAYRVYRDGELVEEVGDVTGLWRDDLVSFLVGCSFTFEAALLEAGVPVRHIETGGNVPMYRTNRDCRPAGRMSGPLVVSMRPVPASMVATAVRITSRYPAVHGAPVHIGEPADLGIGDIDSPDFGEPVEIRPGEIPVFWACGVTPQAAVMQSRPPFAIGHAPGHMAITDARDSEFLVP
What are the official names of this protein?
Putative hydro-lyase SACE_1553.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.