PharMolix/UniProtQA huggingface dataset:
Protein: IRT1_ARATH
Sequence: MASNSALLMKTIFLVLIFVSFAISPATSTAPEECGSESANPCVNKAKALPLKVIAIFVILIASMIGVGAPLFSRNVSFLQPDGNIFTIIKCFASGIILGTGFMHVLPDSFEMLSSICLEENPWHKFPFSGFLAMLSGLITLAIDSMATSLYTSKNAVGIMPHGHGHGHGPANDVTLPIKEDDSSNAQLLRYRVIAMVLELGIIVHSVVIGLSLGATSDTCTIKGLIAALCFHQMFEGMGLGGCILQAEYTNMKKFVMAFFFAVTTPFGIALGIALSTVYQDNSPKALITVGLLNACSAGLLIYMALVDLLAAEFMGPKLQGSIKMQFKCLIAALLGCGGMSIIAKWA
What is the function of this protein?
High-affinity iron transporter that plays a key role in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer.  Acts as the principal regulator of iron homeostasis in planta.  Also mediates the heavy metals uptake under iron-deficiency by its ability to transport cobalt, cadmium, manganese and/or zinc ions.
What are the official names of this protein?
Fe(2+) transport protein 1, Fe(II) transport protein 1, Iron-regulated transporter 1.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus, trans-Golgi network. Vacuole. Note=Cycles constitutively between early endosomes and the plasma membrane and is targeted to the vacuole for degradation.
Protein: GI_GAHVM
Sequence: MYLLQLLFWIRLFRGIWSIVYTGTSVTLSTDQSALVAFCGLDKMVNVRGQLLFLGDQTRTSSYTGTTEILKWDEEYKCYSVLHATSYMDCPAIDATVFRGCRDAVVYAQPHDRVQPFPEKGTLLRIVEPRVSDTGSYYIRVALAGRNMSDIFRMAVIIRSSKSWACNHSASSFQAHKCIRYVDRMAFENYLIGHVGNLLDSDSELHAIYNITPQSISTDINIITTPFYDNSGTIYSPTVFNLFNNNSHVDAMNSTGMWNTVLKYTLPRLIYFSTMIVLCIIALAIYLVCERCRSPHRRIYIGEPRSDEAPLITSAVNESFQYDYNVKETPSDVIEKELMEKLKKKVELLEREECV
What is the function of this protein?
In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions.  Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions.  Implicated in basolateral spread in polarized cells.  In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.  Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips (By similarity).
What are the official names of this protein?
Envelope glycoprotein I.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein I family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN). The heterodimer gE/gI then redistribute to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: SPOT_MYCPN
Sequence: MFYNWLKLYKFSKMATLVEIERDFLQKTAQKFAPEVVALITKALDYSKKWHGEQKRLSGEPFFIHPLRTALRLVEWNMDSNTVCAGLLHDIIEDTQVTEADLTAIFGKEITDLVVKVTKITSESKKQRQLNRKKEDLNLKSLVNIAMSSQQEVNALVLKLADRLDNISSIEFLAVEKQKIIAKETLELYAKIAGRIGMYPVKTQLADLSFKVLDPKNFNNTLSKINQQKVFYDNEWGNFKKQLEEMLEQNQIEYRLESRIKGIYSTYQKLTFHEQNIAKIHDLFAIRLIVKSELDCYHLLGLIHLNFTVLMKHFKDYIASPKQNFYQSIHTTVRLKGLNVEIQIRTQRMDHVSKYGFASHWIYKEKKEGLLASALQVNYLNSKQMHSRDFFKRIFGTDIIKVNVSSDNEPNIVKKLNVESNSKLLDIAYELYPKQFNKLEKIKLDGVEVMSFDVTAENEMVIEFCFGKTNNLKRRWLRYMNNHVFRERVKKDLNKLKKAVKYSELPLYEKALEELHLKLADETQIKQRLNALGIKKLTEFLELIEYPHFPKNEHLYFLASNNQKWRELIKPIKFALSQAVFQNSYFEQIEGIYITKIVIETCCTKIPDMPEQVIGILMKNILRVHLHDCRELANQKQPKIIPLYWNAHQLKMRPRKFRCQINIRGVWSETTVNKIVQTIIEGDSYLERIIPKIDKQKDEFELNITMFIDNYHQLITIMEQITTKNISYVWKYL
What is the function of this protein?
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  This enzyme catalyzes the degradation of ppGpp into GDP.  It may also be capable of catalyzing the synthesis of ppGpp (By similarity).
What are the official names of this protein?
Probable guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: TCF19_MACMU
Sequence: MLPCFQLLRIGGGRGGDLYTFHPPAGAGCTYRLGHRADLCDVALRPQQEPGLISGIHAELHAEPRGDDWRVSLEDHSLQGTLVNNVRLPRGHRLELSDGDLLTFGPEGPPGTSPSEFYFMFQQVRVKPQDFAAITIPRSRGETRAGAGFRPMLPSQGAPQRPLSTLSPAPKATLILNSIGSLSKLRPQPLTFSPSWGGPRSLPVPAPPGEVGNAPSAPPPRNRRKSVHRVLAELDDDSQPSESPPPVLMEPRKKLRVDKAPLTPTGNRRGRPRKYPVSAPMAPPAVGGGEPCAAPCCCLPQEETVAWVQCDGCDVWFHVACVGCSIQAAREADFRCPGCRAGIQT
What is the function of this protein?
Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.
What are the official names of this protein?
Transcription factor 19, TCF-19.
What are the subcellular locations of this protein?
Nucleus.
Protein: GNGF_STRPN
Sequence: MRKPKITVIGGGTGSPVILKSLREKDVEIAAIVTVADDGGSSGELRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSEMQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNVYVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEIAYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYLVQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKJ1_YEAST
Sequence: MTTSILDTYPQICSPNALPGTPGNLTKEQEEALLQFRSILLEKNYKERLDDSTLLRFLRARKFDINASVEMFVETERWREEYGANTIIEDYENNKEAEDKERIKLAKMYPQYYHHVDKDGRPLYFEELGGINLKKMYKITTEKQMLRNLVKEYELFATYRVPACSRRAGYLIETSCTVLDLKGISLSNAYHVLSYIKDVADISQNYYPERMGKFYIIHSPFGFSTMFKMVKPFLDPVTVSKIFILGSSYKKELLKQIPIENLPVKYGGTSVLHNPNDKFYYSDIGPWRDPRYIGPEGEIPNIFGKFTVTS
What are the official names of this protein?
CRAL-TRIO domain-containing protein YKL091C.
Protein: RSMG_AROAE
Sequence: MSAATLEQGLAELGLHLSPATQARLAAFATLLQKWNRVYNLTSIRDAGQVVTHHLLDSLAVLPHLEGITTLADVGSGGGLPGIPLALAAPDCHPALAVTSIETVNKKASFQQQAKIELGLANFTVVNERVENVRPEAKFDAVISRAFSELLDFVGLTAHLLRPGGRFLAMKGVYPRDEIARLPAGFRVVEVHPLTVPGLGAERHLIILERN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_VIBVU
Sequence: MQTQRLRIAIQKKGRLSEECQGLLKKCGVKFNIMGERLVVHSENMPIDLLLVRDDDIPGLIMDGVVDLGFIGENVLEEVRLERKATGDACQFETLSRLDFGGCRLSIAIDKDEKYNGPQDLAGKRIATTYPQLLKAYMDRQGVPFSTCMLTGSVEVAPRAGLADAIADLVSTGATLEANGLKEAEVIFQSKATLIQRSGEFAQDKQALIEKLLTRMQGVQQAKESKYIMLHAPVDKLEQIKALLPGAEDPTVLPLSAEKQRVAVHLVSTENLFWETMEQLKELGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSPA_HYDTT
Sequence: MVKLILVRHAESEWNPVGRYQGLLDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLTALEIAEAKNLEVIKEDRIIEIDHGMWSGMLVEEVMEKYPEDFRRWVEEPHKVEFQGGESLASVYNRVKGFLEEVRKRHWNQTVVVVSHTVPMRAMYCALLGVDLSKFWSFGCDNASYSVIHMEERRNVILKLNITCHLGEFYVEAHKAI
What is the function of this protein?
Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate.  Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate.  Does not display phosphoglycerate mutase activity.
What are the official names of this protein?
Phosphoserine phosphatase 1, PSP 1, PSPase 1, Metal-independent phosphoserine phosphatase 1, iPSP1, O-phosphoserine phosphohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the histidine phosphatase superfamily. Metal-independent phosphoserine phosphatase family.
Protein: MDH_THET8
Sequence: MKAPVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEIPQAMKALEGVVMELEDCAFPLLAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKKDVKVLVVGNPANTNALIAYKNAPGLNPRNFTAMTRLDHNRAKAQLAKKTGTGVDRIRRMTVWGNHSSTMFPDLFHAEVDGRPALELVDMEWYEKVFIPTVAQRGAAIIQARGASSAASAANAAIEHIRDWALGTPEGDWVSMAVPSQGEYGIPEGIVYSFPVTAKDGAYRVVEGLEINEFARKRMEITAQELLDEMEQVKALGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: VKIL_BPHK0
Sequence: MRNEIAINHQMLRAAQNKAVIARFIGDSKMWLEANKAMKSAINLPWYRRK
What is the function of this protein?
Gene kil kills the host upon prophage induction.
What are the official names of this protein?
Protein kil.
Protein: HIS7_LARHH
Sequence: MRQATVTRNTLETRITVSLNLDGSGQARFDTGVPFLEHMLDQIARHGLIDLDITAQGDLHIDAHHTVEDLGITLGQAFARAIGDKKGIRRYGHAYVPLDEALSRVVLDLSGRPGLEYHVDYTRATIGSFDVDLFSEFFHGFVNHAMVTLHIDNLRGINSHHQAETIFKAFGRALRMAVEPDPRMAGVTPSTKGTLTA
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_HELP2
Sequence: MKASIYDFTLKELSQLLKPSFRAKQLYLWLYAKYKTSFKDMQNNFSKDFIAYLEREFTLRTIEITHVRESVDGSKKYLFKSLRDNHTFEAVLLKMKDKKIDKETNAILEGEKYTVCVSCQIGCQVGCAFCFTQKGGFVRNLKASEIIQQALLIKEDNNLPIEKALNIVFMGMGEPLNNLDEVCKAIEIFNTGMQISPKRITISTSGVADKIPILAGKNLGVQLAISLHAVDDKTRSSLMPLNKKYNIECVLNEVKKWPLEQRKRVMFEYLLIKDLNDGLDCAKKLLKLLNGIKSKVNLILFNPHEGSKFERPSLESARMFADFLNSKGLLCTIRESKALDIEAACGQLREKKLSQQI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_KORVE
Sequence: MERLGQPAYRSRQLWQGLYRDRIASLDQFTTLPIPLREELKSSGWAIAFPFVQKRFTSTDGTVRYLLQFSDGQSVETVWMPEGDGGEQGDGSEDGPSYDRATICVSSQVGCAVDCQFCMTALLGLLRNLSAGEIVGQILAVLKDENVDVEKSRINLVFMGQGEPFLNFDNFVKAVTLLAEAVGIPESRMTVSTSGIVPRIVDFGQLAIRPKLAISLNASNDESRRELMPITKKWTLEKLMSAAREFPLRNRERMTFEYVLLGGVNDSEQNAREVVQLLRGLRAKVNLIAWNPGPEIPFSTPDPQHVEAFQQILIDAGIPTFIRKPRGRDIFAACGQLKRTELVTLS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_STRPS
Sequence: MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSGVATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTVGKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQDVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNETLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVADYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKNHTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIWEALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGLFKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQEQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWKQKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGSNQAKIQELLDAVAGKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCS1_PROM5
Sequence: MIIFKNLILKISSLKFAITLIIFIAITSGVGTFIPQGNDPQEYIDFYNETPIFGLINGYQVIKLQLNHVYTSNWFLFSLILLCISLAACSFRRQIPSLKAALKWTDYKNEKRFYKLQLTTNYKVSQDVNHILKADSLLRKKGWSISKFENRLSARKGLVGKLGPIIVHIGLIILLIGSAYGNFSSQSKEQYLRLGESLDLINENKNSKFTIKLNNFLIERESDGKPKQFISYLNFFSEEQHLNEIKTTQVNHPIRFRGLTIYQADWSVSNIVLEIDSVLYQLKLKPIPEIGDQIWGLLIELGRENKKNYLLTIDNENGPLKVSNIKDFSEMFIYLNDDPIEINSSKLSLKKIIPSSGLIIKNDPSIPFIYLAFTLIILGTIFSLIPTNQIWILFNENSNKLFVGGLSNRNLLGFKKEFQKLSDEIKNN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MOBA_SHEWM
Sequence: MSLRIDAVILAGGMARRMGGNDKGLVELLDKPMIEHSIDRIKPQVKEIMINANRNQSRYADLGYPVFSDEDSGYLGPLAGMITAMGQTQADYLLVVPCDCPLLPLDLVERMLTKIQSEGAELAVASDGKREQPVVLLLKPSLRDSMKAFLDGGERKIDFWYAKHHCVVTEFSDQPNAFINVNTPEQKQQLAEAIAK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_STRT2
Sequence: MGSILMATIKEVKEQLAILRDLDDPRWASFEEDSRTGVQAAIRKRRKAILAELAEEERLEILLNYEKSLYARGIELIAGVDEVGRGPLAGPVVAAAVILPKLCKIKGLNDSKKIPKSKHEAIYNQVMKEAVAVGIGIKDNYVIDDVNIYEATKLAMIEAIEKLNPQPEHLLIDAMNLDLPIEQTSIIKGDANSLSIAAASIVAKVTRDKMMADYEQEFPGYAFAKNAGYGTKEHLSGIDKFGVTPIHRRSFEPIKSIIKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_HYDCU
Sequence: MIGLSEIELAGIAGAYFLGSLSSAIIVCRLMGLGDPRQEGSGNPGATNVKRLYGSKPAAITLLGDMLKGVVPVALANMAGWSPLAIILVGFASFIGHLYPIFFGFRGGKGVATMLGVMFGLSLPIGAAVAGTWLFVAKVLKISSLSALIATALAPLYIYLLADGNMAWVSVTAIMTLILFWRHRSNIERLLKGEEDLIKKQPGASDPKE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPD_TRIEI
Sequence: MNLLIPAAGIGRRMGGSRNKLLLTLLGKSLLSWTLEAAVKSDHITWIGIIGQPIDFPDFQKNISDLSTDKHIELIEGGATRQESVYNGLQALPSAAERVLIHDGARCLATPELLDRCAVEILKCPGIIASVPVKDTIKVVDPSGIIQDTPNRRNLWAAQTPQGFDVKLLKECHKKGQILGWEVTDDAALFEKCGLPVKILEGEETNLKVTTPLDLKIAEFILLKAL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: IXTPA_RHOPA
Sequence: MHRRITGKLVIATHNPGKLAEMRELLAPYGIEAISAGELGLAEPDETGDSFQANARIKAEAAAKAAQLPAFADDSGLAVDALDGAPGIYSARWAGDAKDFAGAMARIERLLQERGATAPERRTAHFVSALCVAWPDGHIEEVEARADGTLVWPPRGTAGFGYDPVFLPEGHSRTFGEMTSIEKHGLPPLGLGLSHRAKAFVKLAEICLAG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ATPA_MYCTA
Sequence: MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKVKKPAPKKKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: A2MG_THEMA
Sequence: MGMKRLIFLVFLLISFSLFGGYAYFSRYPVLHPDEGLSFVISDLENITLNVWKISEEDFLKAVFDPESFNFSLLEITRPIYSKKFSSEEWKEFSFPLKDRGFYFATLVSNEGTVFRRVIDRSLFIVTDLEAIYFSDSEKLRLHVFDSDGDFVEGAEVLLFEDSKLIDRVFTGKDGVVSITKHFDTFYIRYGDSRFFGGVYFSGGGLEREKLFFVTDRPIYKPSDTVHFRGQIFSFEEGLYKAFEKTKVTVSIFDTKKNEVYRSEFETDELGGFSGSMKLPDTASVGLYKVNVDHGGRRYYEYFLVEEYRKPEYKVEIETDKDVYISGEVVNYLVRVKYFNGQPVAKAQVAYYVRAFPEEGSGYLVYRGTDFTDEEGNLRLGVKTEEGFQGSYRLEVIVTDESQRQIEETRSVKVYADNVLISPLDRYVSTSPGKQVRVKVKVTDLSGNPLNGLLTTSSEDSTSTVAVENGEAIVTFTPKEPKSYRIELSFGKANTHFYVYAYCGAGTSSEFVINPATNTVKPGDELSVQILAPGKVMGVLGIVSNRVYDTIPVSFTGSVNLRVRIPKDIPEKNLFISFVGLDDNGRIYKLERLNVLLDTNFTTMKILFDKDQYEPGEMAQITIESNVDRVCLFLVDEAIYAMVGAEPPVLENFLYPYMNYPRTRGGFPHYWRLYVSRNSFRNKLASLPEEKTFADFKQNALPSKLNVREYFPDTALWIPSLKLHNGTARVSFKVPDSITSFRATAYGFSKDRFSQTESEMVVSKKFYLMPHLPSFLRESDVIKISATVFNRTSKTLPVQLTVELPENIELLEGSSSRHFLMEANSSHTETWTVKAVSASEGSFVKFVAVGEDLNDAVSMRLPVERFAFEREFYRIMLLDGKETLEIPGQFISSRIRFLDSIVPLVEDSLKRLIDFPYGCVEQTMSRFFPAVVAASAGIEVENLEEIIQRGLFKLYSYQHNDGGWGWFRFGESDDFMTCYVMEGLYFTMKAGYDVAESVLQRGIEYLRKHPSAYGSYVLDLYGVNHEPFKPESEADLVFLSLSSKEALKQLMNYVVQDEQKAYLNVYSNNPLISEIQLNSVFLRALAKWKEFPELERKVTNYLLLKKDSAFWTSTKDTSFVILALLEAMPEYASTTLKVINSENTFELKPGEERSLVPGSLTVSGKGIVEVEVVYIEVPKEAVSEGLEIKREFYKRYELLIEENKMIVDAFVPIGRGYVPRSIHPVEKEQTEELYILPYKYWKKTIEYRGVPLEINGAEVKIKGETYTFFRIETFNGLILVFFRNEALIYDTEKNTITRYLDVTDAGFMRSGPVFLMKGFVLVGDEKIPVPEDVTGLSCTMDEILLRGENKTYWYRNGEFVDLPFVARRVFFWDGKKLVAENIRFSGSSKTLRNRVFEVVFDVGDVKIELGDIIKTVVRVKGDGNYLIVEDFIPSCAQVLSNYREKGIEENKFSYSWYSSWNAWYSGREIRTDRVALFARYLYGNSFDYVWRATAEGVFHLLPARVYPMYSRGLYAHTDPDVLFIGADFIDGRDDQP
What is the function of this protein?
Protects the bacterial cell from peptidases.
What are the official names of this protein?
Alpha-2-macroglobulin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
Protein: PYM1_BOVIN
Sequence: MATPYVTDETGGKYIASTQRPDGTWRKQRRVKEGYVPQEEVPVYENKYVKFFKSKPELPPGLSPEATAPITASRPEGGEPALSKTAKRNLKRKEKRRQQQEKGEAEALSRTLEKVSLGETAQVPSAPQASRAAPTAASDQPDSAATTEKAKKIKNLKKKLRQVEELQQRIQAGEISQPSKEQLEKLARRRALEEELEDLELGL
What is the function of this protein?
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.  Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs.  Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated.  Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).
What are the official names of this protein?
Partner of Y14 and mago, PYM homolog 1 exon junction complex-associated factor, Protein wibg homolog.
What is the protein family that this protein belongs to?
Belongs to the pym family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by XPO1/CRM1.