PharMolix/UniProtQA huggingface dataset:
Protein: PHEA1_HEMAN
Sequence: MYTKIALLGLVGSAAAFNAPMMTVRRDAIATGAAAAVVAPMLRPAGAAMKKDSKAPCVEVFDERDGCKAAGTQKASGDDGFCVKVSMKAIGFNAAEAASVTKNYGIKRFGAKSV
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycoerythrin alpha-1 subunit, Phycoerythrin PE555 alpha-1 subunit, PE555A-1.
What is the protein family that this protein belongs to?
Belongs to the phycoerythrin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: ESXK_MYCTO
Sequence: MATRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMAQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxK.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: DNAK_GEOMG
Sequence: MSKVIGIDLGTTNSCVAIMEGGEPVVIANSEGSRTTPSMVAFAESGERLVGQQAKRQAVTNPENTLFAIKRLIGRKFDTDEVRKDISISPFKIVKADNGDAWVDVRGKMYSPPEVSAIVLQKMKKTAEDYLGETVTDAVITVPAYFNDSQRQATKDAGKIAGLNVLRIINEPTAAALAYGLDKKKDEKIAVFDLGGGTFDISILELGDGVFEVKSTNGDTFLGGEDFDQRVIDWIADEFKKDQGIDLRGDKMALQRLKEAAEKAKCELSSSMETDINLPFITADATGPKHLTMKLSRAKLEALCAELLDKLEGPCRTALKDAGLSPSEVDEVILVGGMTRMPAVQKRVQEIFGKAPNKGVNPDEVVAIGAGIQGGVLRGDVKDVLLLDVTPLSLGIETLGSVMTKLIDKNTTIPCRKSQVFSTASDNQPAVTIHVLQGEREMASDNKTLGNFELTGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQSIRITASSGLSKEEIDKMVREAESHAADDKKKRELIEARNHADTLAYSTEKSLKEYGDKIGDDEKKKIEEAVAALKKAMEGDDVDAIKQATDALTQASHKLAEAVYAKTQTEGGAQPGAEADGDTGAKGGEKVVDADFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ENGB_BAUCH
Sequence: MIHKYDYHKTHFLFSTSCIKNLLYNVSKEIAFTGSSNVGKSSVINTLTNQKNLARTSKKPGSTKTVNVFEVEPGVNLIDLPGYGYVTMPVALKYHWQHDLIYFLQKCTNLKGLVVLMDIRHPMKFLDKYIIQCAIENKIQVFILLNKADKMNAYACNTQYHTVQQHLSNLESNIKITLFSSVTKLGIKKLKAQLDSWFSIVS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NUOB_BACC0
Sequence: MVINFEELHPNERAELERNIFFSTLEQLKGWARSNSLWPMTFGLACCAIEMMGVGSSHYDLDRFGSFFRTSPRQSDVMIVSGTVTKKMAPIVRRLYDQMPEPKWVIAMGSCATAGGPYVNSYAVVKGVDQIVPVDVYIPGCPPNPAALIYGINKLKEKIRYEAKTGKQVTNK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENA_EUBBA
Sequence: MSKTIIKNIGKIVSGDIKSPVLQADTIVVEDGLIAAIGGEELMKDAGDATIIDAAGSTVTPGLLDTHVHVSGGDYAPRQKTMDFISSALHGGVTTMISAGSPHFPGRPKDAAGTKALAITLSKSYYNARPAGVKVHGGAVILEKGLTEEDFIEMKKEGVWIVGEVGLGTIKNPEDAAPMVEWAHKHGFKVQMHTGGTSIPGSSTVTADDVIKTKPDVVSHINGGPTAISVQEVDRIMDETDFAMEIVQCGNPKIADYVARRAAEKGQLGRVIFGNDAPSGTGLIPLGILRNMCQIASMSDIDPEVAVCMATGNSTAVYGLNTGVIAPGKEADLIIMDTPLGSVAEDAMGAIAAGDIPGISVVLIDGEAVVTKSRNTPPAKRAAKIL
What is the function of this protein?
Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2-formylglutarate.
What are the official names of this protein?
Enamidase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RL14_MYCPU
Sequence: MLQELSVAKVADNSGAKEVGIIRNLGGSVKKSSNIGDVVICSVKKAIPNGIVKKGQVVKAVIVRTKYGIKRENGQHVSFDDNAVVIIKEDKSPRGTRVFGPVARELREKGYLKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NU6M_PARLI
Sequence: MALYLILVLMLFGSTLVFYSLSPYYSALGLVVVSISGCIILSFLGGSFVALVLVLVYMGGMLVVFAYSSAISAERFPSVNNLGEVIGLSVLFSSWVFLSFDNFQDFSNSFSCFISGESLVEAGFYMKGFLVLVGVFVLLVVLVGALIISRGIENTVIRAI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CINAL_MYCBT
Sequence: MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: CCD22_AEDAE
Sequence: MDEIDNIILHSLRQIECNLDEEVISLDDLSPSMLVQVVSKCISLIDPGLELPRTLPPGMAQRFTATASLAEACRTIGYRRDIGYQTFLYSNVAEVRRVLMFLVEKLPKEAADKTSGSGQPVDSATQLENRILSSLQSQLQAPWMPEFCQVGRPEGLSTTSGGESPAQIAFRRFIPRKISVPFVTQGDVAAEVKEFWSRRNLDCLDEGSLVPSLIAANDGAIKTNAKGAIDEVDRQVKLPAINEKLLQYYSKGGTKHRLAEPSGAAASSGTTEKVVLNNITVETKPGKTPLESLQEEIDALQQEIVQHSEEGVQLESSRKETDESIEEYRKTIVRLKEEKKIKERTHILLEDPEVNVKKLEAIIAAGGERMKKLQDQWDAHRIPLVDTLEAYRLKNSDKLSKSQQVLDQIESTRQKCEEVVIDLQTKGAMYARLQKEFEKLNKTVSRTAYTSRILEIIGNIRKQKNGIDQILQDTRSLQKEINNITGQLDRQFTVTDDLIFRNAKKDEHSKRAYKLLVTLHSDCEELIKLVQETGAIKREVRDLEDQIENEKGRNTAANLAQITHDLTEMQNESQRLEESIRRMEVTSRQ
What are the official names of this protein?
Coiled-coil domain-containing protein 22 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
Protein: QUEA_EXIS2
Sequence: MDVNLFDFHLPEEQIAQVPLLDRTSSKLMVVNRETGALRHEKFHDIVSYFNAGDTLVINDTKVLPARLFGVKEETGGKIELLLLKQTSDDVWETLAKPAKRVKPGTVLSFGDGLLRAECVEALDDGGRILKFSYTGIFYEVLDQLGTMPLPPYIHEQLEDQDRYQTVYARERGSAAAPTAGLHFTPELLQALTDKGVQLAPLTLHVGLGTFRPVSVDDVDSHKMHSEYYELPESSAKILRETRKNGGRIIAVGTTSTRTLETVIRDHGDFVEASGWTDIFIYPGQEIKGIDGLITNFHLPKSTLIMLVSALSTREHILHAYEEAVAQNYRFFSFGDAMFLTREELNR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_USTMA
Sequence: MSAAARIAPQSAAVAAPAPATTAASAIAKAPSADVQSELDRAALEALELDSDVITSVRLDGLALTKIVKHCRDAHPASASGALLGMDLGGTLEISNVFALPNPGRSNSERDEEEDRSSRNATRYTSDMVRLLRDVNADANPVGLYQGCFLGAFLNSSVIDGLAAITGLVERDGAGSRGKGVLIVHDLAQSAQGNTSVKAYRLSPSFVDAHKKGKFHTQSLIDHKLTFSNILIEIPVSLRNTALLDAFLSSISTPSAPGPSIVQPSTSDLLRNPPSAALAPSYTSLNLALEPVLASSLESTLEIMDEHAAEAGNVGFQARQLAREKAKADAYLARKKAENAAREAQGLAPLPIEDVNRLFKIPAEPSRLEATLLLGQIDSSARRLAETAALGVIQLNAAKTGAV
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBPAP_THEKO
Sequence: MAVGDKITISVIKADIGGWPGHSRVHPQLVETAEDVLSKAVEDGTIIDFYVATCGDDLQLIMTHKRGVDSPDIHGLAWKAFEEATKVAKELGLYGAGQDLLKDAFSGNVRGMGPGVAEMEITLRKSEPVVTFHMDKTEPGAFNLPIFRMFADPFNTAGLIIDPKMHMGFRFEVWDILEHKRVILNTPEELYDLLALIGAKSRYVIKRVYPKPGHPIPENEPVAVVSTEKLYEVAGEYVGKDDPVAIVRAQSGLPALGEVLEPFAFPHLVSGWMRGSHNGPLMPVPMHQANPTRFDGPPRVVALGWQISPEGKLVGPVDLFDDPAFDYARQKALEITEYMRRHGPFEPHRLPLEEMEYTTLPGVLKRLTDRFEPIE
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) (PubMed:12065581, PubMed:20348906).  Does not display hydrolase activity against fructose 2,6-bisphosphate, fructose 6-phosphate, fructose 1-phosphate, glucose 6-phosphate, and glucose 1-phosphate (PubMed:12065581).  Exhibits only negligible activity on inositol-1-phosphate (IMP) (PubMed:15317785).  Is essential for the growth of T. kodakaraensis under gluconeogenic conditions (PubMed:15317785).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase, Fructose-1,6-bisphosphatase, FBPase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: CR1_HORVU
Sequence: CKVAHTYIHRRQTTDRFSSLHRPPDPDRWLLLPCCSEEARGPPPSPAPLPARLFPGRASSPLARTPSAGAASACKPLLERLPTPSRRRRRRRATRRARSRMPRTTPWRAPRAPARAWWTRPRMARAR
What are the official names of this protein?
Cold-regulated protein 1.
Protein: RS12_CLOB1
Sequence: MPTISQLVRKGRKTIASASDSPALKECPQKRGVCTVVKTTTPKKPNSALRKVARIRLTNGYEVTAYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDAAGVANRMQSRSKYGAKKPKQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BIOF_HAEIN
Sequence: MDAFKQQLEQLSAKNQYRSIPDLVHQGRYITRENRKMLNMSSNDYLGLASNENLRQSFLQQYGGNFPSFTSSSSRLLTGNFPIYTDLEELVAQRFQRESALLFNSGYHANIGILPALTTTKSLILADKLVHASMIDGIRLSQCEFFRYRHNDYEHLKNLLEKNVGKFDRTFIVTESVFSMDGDVADLKQLVQLKKQFPNTYLYVDEAHAVGVYGQNGLGIAERANVIADIDLLVGTFGKALASMGAYVVCDQILKECLINQMRPLIFSTALPPFNVAWTHFIFERLPQLSKERTHLEQLSAFLRQEVEHRTQIMPSQTCIVPYILGENEATLAKAKDLQEQGYYCLPIRPPTVPKNTSRIRLSLTADMTADEVRQFAVHL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PDXJ_BRASO
Sequence: MSHPPKLRLGVNVDHIATLRNARGGRAPDPVRAALLAIEAGADGITAHLREDRRHIRDDDMARLKAQISRPLNFEMAATEEMVRIALATKPHACCLVPERREELTTEGGLDVVGQHNALAPAIARLSEAGIRVSLFIAADPAQIEMAARLRAPVIEIHTGGWCDAITDGHHDKADAEWQRIVAGARQAYAAGLEVHAGHGLDYATAEQIAALPEIRELNIGYFIMGEALFVGLAESVRTMRAAMDRGRDRATGATA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_PYRHO
Sequence: MNAKIIALLIIGGGLGALTRYYISGVLPVYKDFPIGTLIVNSLASFLLGYIYGLLFSGFDISPEWRIFLGTGFCGGLSTFSTFSYETFSLLREGEIWLAFANITTNILVTIFLVFLGFILARR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_VEREI
Sequence: MKIAQEIRAGNVIMHGKDPMVVLKTEYARGGRGAATVRMKLKSLIANFGTEIVLRADDKIDNVILDKKECTYSYFADPMYVCMDAEYNQYEVEAGNMGDALNYLEDGMALEVVFYDGKAISVELPTSVEREITWTEPAVKGDTSGKVMKPAKIATGFEVPVPLFVAQGDRIEIDTRTGEYRRRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMRT3_HUMAN
Sequence: MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS
What is the function of this protein?
Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates.  Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements.  May regulate transcription during sexual development (By similarity).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_BACSU
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKRYIFTERNGIYIIDLQKTVKKVEEAYNFTKNLAAEGGKILFVGTKKQAQDSVKEEAQRSGMYYVNQRWLGGTLTNFETIQKRIKRLKDIEKMQENGTFDVLPKKEVVQLKKELERLEKFLGGIKDMKDLPDALFIIDPRKERIAVAEARKLNIPIIGIVDTNCDPDEIDVVIPANDDAIRAVKLLTSKMADAILEAKQGEEEAEVAEETAPETETTTA
What are the official names of this protein?
30S ribosomal protein S2, BS1, Vegetative protein 209, VEG209.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MOGR_LISIN
Sequence: MPKSEIRKLLQEIKKQVDEPGNSSATEIKKMASEAGINEQTAEEIYQLLTEFYQAVEEHGGIEKYMHSNISWLKIELELLSACYQIAILEDMKVLDISEMLSLNDLRIFPKTPSQLQNTYYKLKKELIQVEDIPKYKPGRKRKTQKNTKKEKTNIFGKVVPAEFKAPTSIKEQISYDKSREKNLVDLLSGVKSNVQLLSENQGEENNVYDLLKSIYSLSSLAVQKEELDKKYQDLQTKYQELEQENSYLKQQNETMTDSFHTLVLQVADFAYASDLDQIQALPLFSQQLVVTLNQLGVFKENYKQM
What is the function of this protein?
Transcriptional repressor of flagellar motility genes, such as flaA, during extracellular growth at 37 degrees Celsius.  Binds directly to gene promoter region and probably prevents RNA polymerase binding.  At low temperatures, MogR repression activity is modulated by the DegU response regulator in an unknown mechanism (Probable).
What are the official names of this protein?
Motility gene repressor MogR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_SALTI
Sequence: MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYDVGGIAIDNHGHPLPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVAKAYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQEFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADEAATAIEQAINRALEEGVRTSDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_RICPR
Sequence: MASDINALKYKKVLLKVSGEALMGNKQFGHEYEVIKKIAEDIKEVIDLGLEVAIVVGGGNIYRGINAALVGMDRASADYIGMLATVMNALTLQNVMESLGIYTRVLSAIPMMSVCEPYIRRKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCDILLKATQVDGVYDSDPKKNPNAKKYFTISYKDVINNHLQVMDTAAIAVARENKLPIRVFSIKEHGNFARVIQDKGQYTTIGE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM4_MOUSE
Sequence: MSSPASTPSRRSSRRGRVTPTQSLRSEESRSSPNRRRRGEDSSTGELLPMPTSPGADLQSPPAQNALFSSPPQMHSLAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRPDLGSARKGLQVDLQSDGAAAEDIVPSEQSLGQKLVIWGTDVNVATCKENFQRFLQCFTDPLAKEEENVGIDITQPLYMQQLGEINITGEPFLNVNCEHIKSFSKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKSMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEIDRGRIAEPCSCVHCHTTHSMALIHNRSFFSDKQMIKLQESPEDMPAGQTPHTIVLFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVKLLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQVEEEFLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVNMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRFSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALRKLILSKGKTPALKYQQLFEDIRGQSDTAITKDMFEEALRALADDDFLTVTGKTVRLL
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor MCM4, CDC21 homolog, P1-CDC21.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: CHST7_MOUSE
Sequence: MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSHSEQDKGRNCPGLQRSLGVWSLEAAAAGEREQGAEVRSLAEGNPDRSPGSPGNLSAVGEAVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPGERAPDSANLTTAMLFRWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVSLRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDHFHRVLLAHGVDARPGGQARALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPAWLRRRYLRLRYEDLVWQPQAQLRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVETACAPAMRLLAYPRSGDERDRKTVREGETPLETKANWAV
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues.  Preferentially acts on mannose-linked GlcNAc.  Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin.  Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency.  Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc.  Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc.
What are the official names of this protein?
Carbohydrate sulfotransferase 7, Chondroitin 6-sulfotransferase 2, C6ST-2, mC6ST-2, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5, GST-5, N-acetylglucosamine 6-O-sulfotransferase 4, GlcNAc6ST-4, Gn6st-4.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: NOP9_SORMK
Sequence: MGKNRKSKRQLVRDEKRAKKRGLEIEHEEERDIKKQRREEEAHQDAFAPVTDAGYVPPPLDGTYDENAFPGGPEEGRRNGPNTNFEREFFGMLAEQEQEYFRHADELLELNDFPSTEERDIFLQNVYKELRGKELKVASSQSCSRLMERLILLSNTRQKKSLFDAFGGHFISLVTHRFASHCCEKLFLQSAPVVTQELSGEYEQEPLPEGEEETEAMKSSMEDLFLLTLDELEEHLGYLLTDRFGSHAIRALLVILSGRPLDQAGTKSMLQSRKKEYITVEGAAANQSELSSQIRAVPSSFTMAIKKIIDDSTMTMDATALRVLAKHPTGNPTLQLLLELELTMFVKGKEKKEKNKQKKDDEEAEEKKEETQSEVTLLGMLVPDAPAAFADNTTQAAEFVNSMIYDPIGSRLLETLITHCPGKIFKGLQQHIFGPRIQSLLRNDIACYPAIKVLNRLSREDLADAVEKSLPEMASFVDKGRFNVIRTLFERCHIRNGTDEINALLKALTSAYGNDWKKLVPKLCMLDEDVVEEEQKPDPKFQTQEAKNKAFMLNHGCQLVAALLAIPGQPSKAIQASLAALKPAQVMKMATTSHNTSSILVKALQTPATNPTFHKVLVSSLLPHVYELATSQQGSAVLNEIISLPSKPAEPNAPAVPFHMKENIISQLANYESELRETWLGRNVWRTWKGDMWSHRRHDWVRWAKETDPETARVAAIPRKREEKEKEEAEKKPKGYLGKNFDPKKLKGFAAKKFEKKEAEA
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL17_ANOGA
Sequence: MGRYAKEPDNASKSCKSRGSNLRVHFKNTRETALAIKRMPLRRAQRFLKNVIEKKECVPFRRFNGGVGRCAQAKHWGTSVGRWPKKSAEFLLQLLKNAEANADYKGLDVDRLVINHIQVNRAPCLRRRTYRAHGRINPYMSSPCHIELSLTEKEDVVTKATDESEQAKKKLSKKKLQRQKEKMMRNE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.