PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_METS3
Sequence: MMTKKAITVLSGGLDSCVATCVYAEDYEIHGITFNYGQKSFKQELKASEEICKKMGFTHEVIDLPWLNKISNSSLTSDNEIPTLTHEELDDLDICEDTASSVWVPGRNIVFTSIATSYAESIGAEIIIVGWDKEEAATFPDNSKEFLESFNNMLNVGSPQNIEIKAPAIDLNKDEIVKLGDEIKAPMELSYSCYTGHEKHCGVCESCMRRKRAFKLADVKDPSEYNE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CH10_CITBB
Sequence: MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLKVGDKVLFGKYAGSEVKLEGEDFLIMREDDILGVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BORDL
Sequence: MIIAIDGPSASGKSSVSKALSMKLGFKFISSGYLYRIITLIAQRFTLNEYDLLNESKLVDLISQNDIKYNDNSFLLNGVDVISHILTEKIDFQVSLYSSYVNIRKIVNKKLREIVKIQDDDYIIEGRDITTVVFPEAKIKIYLDASVEVRTLRRYNQRDDDMALIELEQALEKRDEIDQNKEYGKLKLGKGVFYIDTSYKSLDDVCDIIIKTFNLKKK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_NITWN
Sequence: MVSGSFDIGDLKRRMQGATQSLKHELGGLRTGRASSSMLDPVQVDAYGSHMPLNQVATISVPEPRLLSVQVWDKSMVKAVEKAIVDSNLGLSPATEGQVLRLRIPELNEERRKELVKVAHKYAEAAKVAVRHVRRDGLDTLKKLEKNHEISEDDEKRLANDVQKATDSVISEIDQLLAGKEKEILTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_ESCF3
Sequence: MFRGATLVNLDSKGRLSVPTRYREELLGNAAGQMVCTIDIHHPCLLLYPLPEWEIIEHKLSRLSSMNPVERRVQRLLLGHASECQLDNAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVREDIDAEQSITENLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LPXK_ECO45
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAIAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGH
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PYRF_CAMHC
Sequence: MKLCVALDLASRDENLAIARALKGLDIWLKVGLRSYLRDGANFLNELKKIDDFKIFVDLKIYDIPNTMADAAEVISNIGADMINLHASSGLRAMSEVMNRLANLREKPLVLAVSALTSFSDDEFYEVYNQNIDEAVLKMSQNAKNAGLDGMVCSVFESLAIKKECGTDFITLTPGIRPFKGNSDDQKRVANIVMAKQNLSDFIVVGRPIYKSFNPRETVEKILQEIL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: PLSY_KLEP3
Sequence: MSAIAPGLVLLAYLCGSISSAILVCRLAGLPDPRDSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAWALGLTPFWLGLVAIAACVGHIWPVFFHFRGGKGVATAFGAIAPIGLDLTGVMAGTWLLTILLSGYSSLGAIVSALIAPFYVWWFKPQYTFPVSMLSCLILLRHHDNIQRLWRRQESKIWTRMKKKKAPEQK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GEDI_ASPTN
Sequence: MKLEQCIVGRDHTDPRKWHHGDGRDGREHRTAPGLVGGSLAGRDPPVERARGDGDGGHEFMSVVVEGGELREQLLGLRIGIEEDRHRDERQAHHRPYRRSTRCTAGSLYIGDFIAGRTTVVGAIGAGPPSQRRFAFPEVNDCGPSSNIFAKCCAPGTILFGNIFDLPNFPRMSDVRAGSNDPPGKYLCLTICGYRKPGMSEEDYRHHMTKISAPMTKDLMVKYGIKRWTMIHSPAVTRTLMDQLYDSQMVNLADFDCFSQVVFKSVEDYKRMKEDPYYKEHLFKDHEHFADTKKSLFVHFMPLPPPLGPCPGS
What is the function of this protein?
Decarboxylase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (PubMed:24009710).  The next step is performed by the emodinanthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Questin oxidase is then involved in the ring cleavage of questin to form desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by one of the methyltransferases identified in the cluster leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Decarboxylase gedI, Geodin synthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: MTNK_GEOTN
Sequence: MAIIQSSAYEPLTEQKATALAVRLGLFRDGTPLLCREIGDGNLNLVFHVVDQETKQGIIIKQALPYAKVVGESWPLTLKRAVIESNALRTFASYVPQYVPKVYYSDESLAITVMEDLSYLQIARKGLIEGKTYPLLSRHIGEFIAKTAFYTSDFGMNQQEKKKLAQSFVNPELCKITEDLVFTDPFFDHDSNNFEDELHLDVETLWNDDRLHLEAAKLKRKFLTEADVLLHGDLHTGSIFASDDETKVIDPEFAFYGPIGFDLGHFIANLLLNALSRPESERRPLFDHIDRTWAVFTSVFSELWRTESVETYAATPGLLDDVLRQTFIDAVGFAGCEVIRRTIGLAHVADLDGIEQKDERLAAKRHALRLGRRLIVERAELDGTEDFRRLFVETER
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: ILVC_PYRFU
Sequence: MVRVVKVWYDNEVSMDILKDKTVAVIGYGSQGEAQAKNMRDSGVHVILGLRPEGNSWKRAQKDGFEVYTIEEATKRADIVHILIPDLVQPKVYKEKIAPYLREGQALGFSHGFNIHYKQIVPPEYVDVIMVAPKSPGRRVREVFLEGFGVPALIAVYQDYTGHAKELALAMAKAIGATRAGVIETTFKDETESDLIGEQLVLVGGLIELIKKGFEVLVELGYPPELAYFEACNEAKLIMDLIYERGFTGMLKAVSDTAKYGGLTVGPKVIDEHVKENMRKYAERVRSGEFAKEWISKADKADEVLKELMKEIEEHEIEKVGRFIRRMSGLEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DNLJ_PELUB
Sequence: MNDKDLEIEYLKKIDLFQRHNKHYYDKNKPIVSDQEFDLLKKDIIDLERKYKFLKSEYSPTKSIGFKPSKNFQKIKHKVPMLSLGNAFNEEDLKNFEKKIINFLSLKDVNTIEYSAEPKIDGISASLIYIDGKLTKGLSRGDGNEGEDITQNLKTIKDIPLEITKSNFPKEIDIRGEVFIENNDFKKIKDKFANPRNAASGSLRQKNSLITAKIPLKFIAYTYGYEKKMNIKNQTSFLENLKLWGFKTNPFNKKIIGVKNLMLNHKELEEKRKELAFDIDGIVYKVNDFDLQKRLGFAANAPRWAIAHKFSANSSISEIMNIEIQIGRTGALTPVAKIKPVNIGGVIVSNATLHNEDEIVRKDIRVGDTVTVERAGDVIPHVVSVDLKKRKQNSKKFIFPLKCPSCGSKTIKDYNETTKRQDAVRRCASEGFECEKIAIERIKHFVSKDAFNIDGFGKKIVENFWNLKLVRLPQDIFKLNYNKIEELEGWGKLSVANLRFSIEEKKNISLERFIYSLGIRHIGQENAKLIARHLKTASNFFRLSGEKNIESLSNIDGIGITQIQSIKKFFLNKTNLKVLSELEKNLLIKDVILINNNGLLKNKTFMLTGKLNGISRAEAKSLIEQNSGKIISNVNKKLDYLIAGDKPTLKKINTAKEWNIKIINQTEWLKMLNKSG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GAR1_BOTFB
Sequence: MSFRGGSRGGRGTGANAGFSGGRGGFGGRGGGRGGFQQRDNGPPADVFAMGSFLHASEGEIVCESINTKIPYFNAPIYLENKTSIGKVDEILGPINQVYFTIKPTEGIQATSFKTGDKFYIGGDKLLPLEKFLPKPKPPPGAPKPKRAGGARGGRGGPMRGGRGGGRGAPRGGRGGFTPRGGSGGFSRGGGGGGFSRGGGGFTPRGGARGGSRGGFSRGGR
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: VIF_HV1YB
Sequence: MENRWQVMVVWQVDXMKIRTWNSLVKHHMYVSKKAKGWYYRHHYETKHPKTSSEVHIPVGXAXLVIVTYWGLTTGEQPWHLGHXVSIEWRQGKYKTQVDPEMADKLIHCYYFNCFTASAIRQAVLGRPVLPRCXYPAGHXQVGTLQYLAXTAXVGVKKRRPPLPSVTKLTEDRWNERQKTQGHRGNPIMNGP
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: PYRC_SHESA
Sequence: MTTLTITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPEEIRKAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPKLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPVSYPLGDNNVVPIRAGEQIDWQVE
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TRMD_BACMK
Sequence: MKIDILTLFPDMFTGVFGSSILKKAQEKEAVELRVVNFREYTTSKHNSVDDYPYGGGAGMVLTPQPIFDAVEELTKETDRKPRIVLMCPQGERFTQKKAEELAGEEHVIFVCGHYEGYDERIREHLVTDEISIGDYVLTGGELASMVVTDSVVRLLPGVLGNQTSQVEDSFSTGLLEHPHYTRPADFRGMKVPDVLMSGNHKNIDEWRHKESLRRTYTRRPDLLEERELSKQEEKWLEQIKEDR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_COXB2
Sequence: MKNQWKTSDFDYNLPVELIAQRPLADRSGSRLLYIDRSRRTVSHRQFNGFVEQVKPNDLVVLNDTKVIPAGLFGHKQTGGKVECLVERILSKDRFLAHIRASKAPKLGSQIIIADNFKIIIEGRYNDLFECVLHSSASILDLLYQHGRIPLPPYIQREPDKDDQARYQTIFAERAGAVAAPTAGLHFNEETFDALRKKGAAITYVTLHVGAGTFQPVRADSLADHRMHHEWMEVSKAVCDAIAKCRKNNGRVIAVGTTVMRCLETATKNGECRPYAGETDLFIYPGFQFKCVDALLTNFHLPKSTLLMLVCAFGGYELVMEAYQKAVENRYRFFSYGDAMLIS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_SHIBS
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: FLHD_SHIDS
Sequence: MGIMHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_LIGS1
Sequence: MANGFKFTPAQQKAIEDTGKNILVAASAGSGKTRVLVERVINKIKQGVSIDELLVVTFTEAAAKEMKERIQIALRKELSTADSEEEKRRYLTQLSKLNVANISTLHAFCLQIIKQYYYVINLDPMFRMLTEDTEVALLQENVWDDLREKWYSKKSPEFENLVVNFSSDRNDDGLSELVMKTYQFANANPNPDEWLNNLVSEYDLGDQPLMESNFYQNKIKPNVLDQIQLAKDNLKQGMDEANKLGLEKLYQTFEQDCATIDELQDFVVGCKEWNNLKTTLQNFKFKRAKSDRGLDDDQKKQKERINKTLRDGSKKIIEDLSVKYFALPEDEIKELTQKSKQIVETLSEVVKEFGAEFSKEKRRRHVLDFSDLEHLTLQILNTDTPDGRRVKERLKNKFKEIMVDEYQDTNQLQETILTTIAHKNPGNMFMVGDVKQSIYGFRLADPGLFLKKYQSFATDDNDDERIILAENFRSMENVTAFTNLIFSQLMDEKVGEMAYDEDARLVYGAKYYPEETPIKAEVLVYESEDSSQESDDEPVNEDFSIDNKAQGQIVMTAKRIKELVENGEKIYDKKQGTIRPIEYRDIAILAPTRKNNLILTEEFKRLGVPIFVPDAQNYFQTTELKIMMSFLQIIDNPYQDIPLVAVLRSPIVGLKENELAYLRINDKTGDYFQAVESFYDNFEVEKASAFAQSLYEKIAIFLKQLTEFRNMAQQNELASLIWKIYEETGFLDYVGGMPGGLQRQANLHALYERAAEYEEMSFKGLFQFVRFINKMQTKNKDLSEATTQVSDDAVTVMTIHGSKGLEFPVVFLLDATHKFNVGDLNKPYLLNADDGIGISYLDPDTRVKTDTLMKVIAGKQALKKLAAEQMRLLYVALTRAEQQLFIVGSYKDKNEALSKWKKATQSESLVLNAGIRASVRNFMDWIGMCLTRSEIFKEVDDTVDAKEPEYIGELPVKFEVKFYSNQDLRGENITLDENSESWLKQQLKKIEEQEPLEINDKQYRIIDKILQSKYPNESLAKTTAYQAVSDLKRAFDDPDNNMMQSLEIDWQDQVPQGINRYVQNELSLPKFMTTKVKVSPAQVGIATHLLLQKLPLDDEVTLEELMQLLAQLVEDKLITSEVAKEINLNQIKVFYTSDLGRKVLKNKDKVKRELPFAMIIPAGRLFSNVDNDVEQPILVHGIIDGLIELDDEVIIFDYKTDHHTSEDKLIENYRGQLNLYAMAVESMLNKKVSQKIIYSLDLGKSIVL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: RS211_FRATO
Sequence: MLSIRVDEHKPFDISLRNFKRACEKAGIKQELRDRQHYVKPTEKRKIAKRQAVKRARISQRRAFI
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NRAM_I96A3
Sequence: MNPNQKIITIGSISIAIGIISLMLQIGNIISIWASHSIQTGSQNHTGICNQRIITYENSTWVNHTYVNINNTNVVAGKDKTSVTLAGNSSLCSISGWAIYTKDNSIRIGSKGDVFVMREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPLGEAPSPYNSKFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWKKRILRTQESECVCVNGSCFTIMTDGPSNGAASYKIFKIEKGKVIKSIELNAPNSHYEECSCYPDTGTVMCVCRDNWHGSNRPWVSFNQNLDYQIGYICSGVFGDNPRPKDGEGSCNPVTVDGADGVKGFSYKYGNGVWIGRTKSNRLRKGFEMIWDPNGWTDTDSDFSVKQDVVAITDWSGYSGSFVQHPELTGLDCIRPCFWVELVRGRPRENTTIWTSGSSISFCGVNSDTANWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: EDL16_ARATH
Sequence: MAIREIKDVERGEIVNKVEDLGKPFLTHEDDEKESENNESYLMVLFSTFVAVCGSFEFGSCVGYSAPTQSSIRQDLNLSLAEFSMFGSILTIGAMLGAVMSGKISDFSGRKGAMRTSACFCITGWLAVFFTKGALLLDVGRFFTGYGIGVFSYVVPVYIAEISPKNLRGGLTTLNQLMIVIGSSVSFLIGSLISWKTLALTGLAPCIVLLFGLCFIPESPRWLAKAGHEKEFRVALQKLRGKDADITNEADGIQVSIQALEILPKARIQDLVSKKYGRSVIIGVSLMVFQQFVGINGIGFYASETFVKAGFTSGKLGTIAIACVQVPITVLGTILIDKSGRRPLIMISAGGIFLGCILTGTSFLLKGQSLLLEWVPSLAVGGVLIYVAAFSIGMGPVPWVIMSEIFPINVKGIAGSLVVLVNWSGAWAVSYTFNFLMSWSSPGTFYLYSAFAAATIIFVAKMVPETKGKTLEEIQACIRRET
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Sugar transporter ERD6-like 16.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECA2_BORA1
Sequence: MESFSALAPDPLYPEKESERHANKLEAWGTAVLRWLSRKRRQPLWRTRRILKQVHAEAALLAGLDLAGVRARADEVAFELRCDGITQASAARAFALVRQAGKLALGKAHFDVQLLGGWAMLQGMVAEMNTGEGKTLTATLPAATAALAGLPVHVITTNDYLVERDAQIMSPLYEALGLTVRWVSMDMEPAQRRLAYQADIVYCSNKTLVFDYLRDLIVLDDDKDEDRLRLERLRGGSGRLSELFLRGLCFAIVDEADSVLVDEARTPLIISGSQKEDGGAVTGQALALAQAMQAGHYRVQPAARRVVLTEAGRAYLREACAAWPAPWSIPFRREELILSALTVLHLYKRDEQYIVRDGKVMVVDEFTGRVMPDRSWGQGVHQMIEHKEGLELSDPRVTLKSISYQRFFKHYLRLAGMTGTAAEIRGELGRVYNLPVVRIPTHRPSRRLHAPDSVYRTMAEKWSAVRERCRELHGRGVPVLIGTRSVAASEELARVLADAALPVVLLNAKQDADEASLIARAGEVGSIMIATNMAGRGTDIPLSAAARQAGGLHVILTERHESARIDRQLEGRSGRQGDPGHTEAILSLEDAVLDSVKNSLWAGPMNTLLAAQGPGWRGLAAHWLRHAQARTERKLARERRAMVSADEELENSLSFSGQGD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.