PharMolix/UniProtQA huggingface dataset:
Protein: RNFA_VIBC1
Sequence: MTEYILLLVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAYLVESYVLRPLGIEYLRTMSFILVIAVVVQFTEMVVHKTSPTLYRLLGIFLPLITTNCAVLGVALLNINENHNFIESIIYGFGAAVGFSLVLILFASMRERIAAADVPVPFRGASIAMITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AHC2_YEAST
Sequence: MITPKGTHDAVAKFQKTDLHQDLDYIVLQQRRTQLETLINERESFVKNLCSLFHKIQNTKNYQEFVDVLAENRDLLREIFTVENGFQKQKWISNDDIPQIDWDKFALDINAYIAENDQLLALYEDGLL
What are the official names of this protein?
ADA histone acetyltransferase complex component 2, Putative transcriptional regulator AHC2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PURT_SHESR
Sequence: MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYPNAPAMQIAHRSHVINMLDAKALRAIIELEKPHLVIPEIEAIATQTLVEMEAEGLNVVPTARATQLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAIGKIGVPCVVKPVMSSSGKGQSVIRDVSQSAKAWQYAQEGGRAGGGRVIVEGFIPFDYEITLLTISAVNGIHFCAPIGHRQEDGDYRESWQPQAMSADVLAKSQAIASKVVEALGGYGLFGVELFVKGNDVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVVLVEGKSKNIRYQGLADALAAENTQLRLFAKPEIDGRRRLGVALARDKDIESAVNKALDSASKVKVIF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL23_PROM2
Sequence: MTKLFDSRLADVIRKPVITEKATNALDLNQYTFEVDHRAAKPEIKAAIEALFSVKVIGVNTMNPPRRTRRVGKFSGKRSQVKKAIVRLAEGDKIQLFPES
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ENOA_ANAPL
Sequence: MSILKIHAREIFDSRGNPTVEVDLYTNKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALISKNVNVVEQDKIDKLMLDMDGSENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMIPPCGADSFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIGKAGYSDKVVIGMDVAASEFYRDGKYDLDFKSPDDPSRYISPDQLADLYKGFVKNYPVVSIEDPFDQDDWGAWKKFTGSVGIQVVGDDLTVTNPKRIAKAVEEKACNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKARFAGRNFRNPRIN
What is the function of this protein?
Both an enzyme and a lens structural protein.
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Tau-crystallin.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRNIP_DANRE
Sequence: MVQEFNVLRCFSCQTFQVQQVKKAKKWTCKVCGEKQSLIKEFGRGAAADCRRHVQKLNALRGEQHQLNTQQLLAQGDEENENEDVYEVLDPKSEQEEAHVSRWSKYTDQTTEGPNEEKDDEDEDENVYTERPQFRIQGTRKRKKMSSLEPFGGNCDNYEESRAGYSQFRKQAYLPLQLEKRSSSSWNKGSVSKYSNCQRPDDVVPSARTKLPSSRQTVGHYPTACSSSTNTMENSIGNKQQIKSSYRPPTADVNKHLPIQSESPSVSSHQKFGESTIENKDSKWNKFLTIVPTQDKEEYYYESQNGKKTLIPYFTKADTVVDFEERRCPADEKDSGILNRQKVVGGNASCPTTRLPTKSVGFENAVCKPVLVKAPYSSLSLNPLFCTDEDFDDTS
What is the function of this protein?
Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex.  Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.
What are the official names of this protein?
MRN complex-interacting protein, MRN-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the MRNIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm.
Protein: XYNA_ASPOR
Sequence: MVSFSSILLACSAAIGALATPIEPLADHPNEAFNETAFNDLVGRSTPSSTGYNNGYYYSFWTDGGGDVTYTNGNGGSYSVQWSNVGNFVGGKGWNPGSSRAITYSGSFNPSGNGYLAVYGWTTDPLIEYYIVESYGTYNPGSGGTYKGQVTSDGGTYNIYTSVRTNAPSIIGTATFTQFWSVRTSKRVGGTVTTGNHFNAWAKYGLTLGTHNYQIVATEGYQSSGSSAITVY
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A, Endo-1,4-beta-xylanase G2, Xylanase G2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEN3F_PENVA
Sequence: MRLVACLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSCCSRLGRCCHVGKGYSG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-3f, Pen-3f.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: Y758_AQUAE
Sequence: MRYFVIGTMIALAGLLVGGGVGSYFTSSKLLKQFQNIPGSPIVLSATYNKEKHLIAYTISNPGTLPIKITEKAFVFTPGKESKEKGYVLSNIPANVTIPPLSVAIVELKLKEGTEKLKVGDLVVATFTYTHPLSQDIYTVVHPFTYGVKEKQQTEKKEEKKEESK
What are the official names of this protein?
Uncharacterized protein aq_758.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CBBQ_HYDTE
Sequence: MDLRNQYLVRSEPYYHAVGDEIERFEAAYANRIPMMLKGPTGCGKSRFVEYMAWKLGKPLITVACNEDMTAADLVGRFLLDKEGTRWQDGPLTTAARIGAICYLDEVVEARQDTTVVIHPLTDHRRILPLDKKGEVVEAHPDFQIVISYNPGYQSAMKDLKTSTKQRFAAMDFDYPAPEVESEIVAHESGVDAATAKKLVEVAIRSRHLKGHGLDEGISTRLLVYAGSLITKGIAPLIACEMALICPITDDPDLRYALRAAAQTLFA
What is the function of this protein?
May affect the post-translational activation and/or assembly of the oligomeric structure of RuBisCO.
What are the official names of this protein?
Protein CbbQ.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: LPXC_BRUA1
Sequence: MNAYQKTIGRAVTLSGVGVHGGAPASARLLPADADTGILFQRSDIKDSAPVCAHVSQIGATDLCTSLGAREARIDTVEHLMAAISALGIDNLVVEIEGPEVPILDGTSARFIEAVDSVGVVTQDAKRRFIRILKTVRVEAGNSWGEFRPYDGTRFEVEIDFECPLIGRQKFAHDVDEETFRKELSTARTFGFMKDVERLWAAGLALGASLDNSLVIGDDNSIVNADGLRFKDEFVRHKTLDAVGDLALAGLPFIGCFSSYRGGHRLNSEAVKALLSDETAFEIIEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: LEUC_SALTI
Sequence: MAKTLYEKLFDAHVVFEAPNETPLLYIDRHLVHEVTSPQAFDGLRAHHRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCNEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTVVTLRAEEIAPQVTWGTNPGQVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPLTDVAIDKVFIGSCTNSRIEDLRAAAEVAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRSIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DNAK_STAEQ
Sequence: MGKVIGIDLGTTNSCVSILEGDEPKVIQNPEGARTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQELSAMILQNLKSTAENYLGDTVDKAVITVPAYFNDGERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTETDQKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVSEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEISLTRSKFEELADSLIKKTMEPTRQALKDAGLSTSEIDEVILVGGSTRIPAVQEAVKKEIGKEPHKGVNPDEVVAMGAAIQAGVITGDVKDVVLLDVTPLSLGIEIMGGRMNTLIERNTTIPTSKSQVYSTAADNQPAVDIHVLQGERPMASDNKTLGRFQLTDIPPAPRGVPQIEVTFDIDKNGIVNVTAKDLGTNKEQNITIQSSSSLSDEEIDRMVKDAEENAEADKKRREEVDLRNEADSLVFQVEKTVKDLGENISDEDKKNAEEKKDALKTALEGEDIDDIKAKKEELEKVIQELSAKVYEQAQQAQQQGQEEQGSQDSTVEDADFKEVKDDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NRDR_TRIEI
Sequence: MLCPICQDTNSRVLESRSAESGKSIRRRRECMNCQHRFTTYERIEFLTITIIKRDGKKESFDKSKLLRGIIRSCEKTGIEVSQLEAFVNQIEVELQGKCQREITSAEIGEIVLSKLSGISEVAYIRFASVYRKFQGIRDFVDTLNHLQNQKENLEFTATVPQNSEISLQQDVINV
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AROA_STAA3
Sequence: MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYKPLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSKEPTIIKELDVSRNHTETMFKHFNIPIEAEGLSINTTPEAIRYIKPADFHVPGDISSAAFFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_DICDI
Sequence: MMEKSKPNVVFVLGGPGSGKGTQCANIVRDFGWVHLSAGDLLRQEQQSGSKDGEMIATMIKNGEIVPSIVTVKLLKNAIDANQGKNFLVDGFPRNEENNNSWEENMKDFVDTKFVLFFDCPEEVMTQRLLKRGESSGRSDDNIESIKKRFNTFNVQTKLVIDHYNKFDKVKIIPANRDVNEVYNDVENLFKSMGF
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and CMP as phosphate acceptors.
What are the official names of this protein?
UMP-CMP kinase, Deoxycytidylate kinase, CK, dCMP kinase, Uridine monophosphate/cytidine monophosphate kinase, UMP/CMP kinase, UMP/CMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS7_NAUPA
Sequence: MRRRRAPKRPVMPDPVYNSEVVTKFINKVMWDGKKTLAERIVYGAIEKLGEKGEEKGIDLFFKAIENVKPLLEVRSRRVGGATYQVPMEVRPERQQTLSIRWIVDAARNRNERTMVERLANELFDAANERGAAFKKREDTHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HEM1_HERAR
Sequence: MQLLAVGLNHTTAPVSLREKVAFPADQLGQAVASARVWYGRSDSKTYSDEAAILSTCNRTELYAASHQPGGVNEAIDLTAHFLADYHKLPYSELRPYLYALPQDNAVRHAFRVASGLDSMVLGEPQILGQMKDAVRQAEAAGGLGTYLHQMFQRTFAVAKEVRSNTEIGAHSVSMAAASVRLSQRIFDTISEQNVLFIGAGEMIELCATHFAAQNPKSLTIANRTLERGETLAHRFNGRAIRLADLPDQLASYDIVISSTASSLPIIGLGMVERAIKARRHKPMFMVDLAVPRDIETEIGRLDDVFLYTVDDLGTFVQTGLENRQAAVTQAEAIIETRVQSFMHWIDARAVVPVIQDLHESSEMMRMIELERARKLLAKGEDIDAVLEALSKGLTAKFLHGPQQALNNAQGDERTRLAALLPQLFRTKR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NORR_ECO7I
Sequence: MSFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWAASARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: TSN1_PONAB
Sequence: MQCFSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALMTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDFEDSPYLKENHAFPPFCCNDNITNTANDTCTKQKAEDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYCNLQ
What are the official names of this protein?
Tetraspanin-1, Tspan-1.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: ESF2_CANGA
Sequence: MVSNKHDDFSEDDFSDQEDGILLQKKKVVRDAFSKEDSDVEEGISDEEADVAEQPHSEDKEESAEAQLEQNKAEQTNEQQAGVAEPVSEEKRKQSKIDKIIQRKAGQKLKHKTGVVYLSRIPPYMKPAKMRQILSRFGEIDRLFLKREDEAKHKQRTRGGGNKKIMYEEGWAEFIRKRDAKLCAETLNGNIIGGKKGSFYHDDILNVKYLPGFKWADLTEQIARENDVRQAKLELEISQSNKLNAEYIRNVEQSKMLQNMRKRKDHEDRDQDARRQFKQHKVSTNRADAPSSIKNKSETSVKDVLSSLL
What is the function of this protein?
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis.  Required for the early cleavages at sites A0, A1 and A2 (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein ESF2, 18S rRNA factor 2.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YEGS_ECOUT
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGGVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEIIPTLVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_SULNB
Sequence: MARTHKLEDVRNIGIAAHIDAGKTTTTERILFYTGVEHKIGEVHDGAATMDWMEQEQERGITITSAATTCEWLGKQINIIDTPGHVDFTIEVERSMRVLDGAVSVFCAVGGVQPQSETVWRQRNRYGVPSLVFVNKMDRTGADFLEVERQIRDRLKGNPLVIQLPIGAEENFEGVVDLVKMKEIVWDADAEMGSAYHEQDIRPELQEQAEAFREKLIEGISEVDGNEELMEKYMEGEELTTEEIMAGIKAATIHMHVVPMLPGTAFKNKGVQTLLDAVVHYLPSPVEAPPIKGTKMEDEDVEVVVESTDDGEFASLAFKIMTDPFVGQLTFIRVYRGSLESGSYVLNSTKEKKERVGRIMKMHAIKREEISEIYAGEIGAVVGLKNTTTGDTLCSDKDKVVLERMDFPDPVISVAVEPKTKADQEKMGIALSKLAAEDPSFRVNTDEESGQTIISGMGELHLEILVDRMKREFKVEAEVGAPQVAYRETIRKAVNKEYKYAKQSGGRGQYGHVFLKIEPQEPGFGYEFVDAVKGGVVPKEFIQPVNKGVQEAMARGIQAGYPVEDVKVTLYDGSYHDVDSSEMAFKLAGSMGFRDGCREANPVILEPMMKVEVEVPEEFMGDVIGDVAKRRGQVSGMDDRAGNKIVNAFVPLSEMFGYSTDLRSMTQGRATYAMEFDHYEEVPQNVAKEIIEKRNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFAP4_HUMAN
Sequence: MEYFMVPTQKVPSLQHFRKTEKEVIGGLCSLANIPLTPETQRDQERRIRREIANSNERRRMQSINAGFQSLKTLIPHTDGEKLSKAAILQQTAEYIFSLEQEKTRLLQQNTQLKRFIQELSGSSPKRRRAEDKDEGIGSPDIWEDEKAEDLRREMIELRQQLDKERSVRMMLEEQVRSLEAHMYPEKLKVIAQQVQLQQQQEQVRLLHQEKLEREQQQLRTQLLPPPAPTHHPTVIVPAPPPPPSHHINVVTMGPSSVINSVSTSRQNLDTIVQAIQHIEGTQEKQELEEEQRRAVIVKPVRSCPEAPTSDTASDSEASDSDAMDQSREEPSGDGELP
What is the function of this protein?
Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'-CAGCTG-3'.
What are the official names of this protein?
Transcription factor AP-4, Activating enhancer-binding protein 4, Class C basic helix-loop-helix protein 41, bHLHc41.
What are the subcellular locations of this protein?
Nucleus.
Protein: DSK1_CYLFU
Sequence: MNAANRRKSTSTVGITGRKDATRMKIEQMEKERKERRKTMMQRKEARKQEHMKNIEAGNPGDVDFIGLVEEWRREQENKIGDKSPPSLFASTNSNICIAVRKRPISDKERQKLDHDSVSCFQNKVWIHSAKLKVDGITKYLTHNSFQLDHTFGEDSTTEQIYLATTLPLVDHVVSTQGRATVFCYGQTGSGKTYTMNGIQQILAYDLYGQLAEHTDDLEITVAFFELYSGNVLDLLHGCQRCKLLEDGNGEVNITGLREVPAPTPEAFLQVIEEGHSLRTTQKTEANDASSRSHAICQVFLRDYGGNLRGKLGLVDLAGSERGSDTKQHNSQRRTESADINTSLLALKECIRALGQKSAHVPYRGSKLTLILKDCFSPDSKTTMVATVSPGASAADHSLNTLRYADRIKEQRVSSNGQRGKAAKASNREIMPSKERLMRIAAATEQADDQHSAFVQKMLAEHDQVQADANDYAFTEQVDEEEADDEEGDYEEESEDLDYEDSEGQDYEEAVESQYDHSQEAQEGEEELRRTVQAVFELEEALLNQHMSNIQANAEMLTQEGKLLQSVQAGGLSEDEMHNYAIQLAEFLDKKESLIYKLQSKLDEFQEQLAREQELARQVQLTQY
What is the function of this protein?
Involved in anaphase spindle elongation.
What are the official names of this protein?
Diatom spindle kinesin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS16_VEREI
Sequence: MVVIRLSRGGAKGRPFFNIVVADKRVRRDGRFIERLGFYNPTAKENEEGLRIMQDRLTYWKSVGAQSSPTVERLVKQAAKQMA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PACE1_HUMAN
Sequence: MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLLSHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKIFKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHIQRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPENQTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQKPIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFTIQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAEITEGEAEGWEEEGELNWEDNNW
What is the function of this protein?
May play a role in regulating cell adhesion/migration complexes in migrating cells.
What are the official names of this protein?
Protein-associating with the carboxyl-terminal domain of ezrin, Ezrin-binding protein PACE-1, SCY1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
Protein: EHD3_RAT
Sequence: MFSWLGNDDRRKKDPEVFQTVSEGLKKLYKTKLLPLEEYYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDVEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNAVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRPVQMVKGGAFEGTLQGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDEEFALANHLIKVKLEGHELPSELPAHLLPPSKRKVAE
What is the function of this protein?
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis.  In vitro causes tubulation of endocytic membranes.  Binding to phosphatidic acid induces its membrane tubulation activity.  Plays a role in endocytic transport.  Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport.  Involved in the regulation of Golgi maintenance and morphology.  Involved in the recycling of internalized D1 dopamine receptor (By similarity).  Plays a role in cardiac protein trafficking probably implicating ANK2.  Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction.  In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function.  Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance.  Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing.  Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with Ehd1.
What are the official names of this protein?
EH domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the ciliary pocket from where the cilium protrudes. Colocalizes with RAB8A and MYO5B to a cytoplasmic tubular network devoid of RAB11A. Colocalizes with ANK2 in myocyte perinuclear region. Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals.