PharMolix/UniProtQA huggingface dataset:
Protein: IPDA_MYCTO
Sequence: MPDKRTALDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFTTAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation.  Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA).
What are the official names of this protein?
Cholesterol ring-cleaving hydrolase IpdA subunit, (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit, COCHEA-CoA hydrolase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: PEPX_LEVBA
Sequence: MRNQQFAIRPTTLDQARVELQQIHFLDDTNLSFTTPSDLLRDFYDRSWPEYTTSSVVAQQLSNLMATPETDGLTYLTTHEQVPVDVFYNLALQRLGFAVDLDFQLTDPLAAMTKIQLPVADHEGTTFTLNELMNAWYVLLTTHNKTGQTFLDQLTTHGYFAPLIHDNSVPKPLIFNGKAQAVFDTTQLIHEVVYVESPQDTDHDGHRDLLKAEIIRPAETANGLKVPVLYTASPYNQGTNDEAGEALTHNVNVPLTAKQPAATTLADVTAESVTTPLPDARPVTATTHTAAETFAREQSYTLNDYFLARGFAVVYAAGIGTKDSDGLRTTGDPEETTSTIAIIEWLAGNRTAFTTRNATQAIPAWWSNHQVAMTGRSYLGTLATAAATTGVAGLKTVISEAAISNWYDYYRDGGLVVAPGGFPGEDADVLAEETFSRQLLAGDYHRIQEKWQHQLAAITQNQDRVTGNYNRFWDARNYLKNAKNIKADLLLVHGLNDWNVKPRNVNNLWRAVRDLPVTKKLILHQGQHIYINAFRSIDYTDIVNLWLTHELLGVDNHAETLLPNVIIQDNVTPETWQAYPDWDAPSNPVQHFNLQADELVAPSDHIPAAATSFNDQLPVDQFNHYTHHIDEWQADLLGDKHNAMFKHRLLFKSAVLTDDLVLDGRPTIDLQVAVNQPLGLLSFQLVDYGDAKRLGVSPTPLRIRLDEGYRWREDNLREFTVAATTPWKMITKGHRNLQNRTNAYQVDELKPNTFYDLSVTLQPTHYRLLAGHQLGLVIYATDFGMTVRGNQDLQYSIQLGQSALHVPFITD
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERO1B_MOUSE
Sequence: MSPGFRRAVTGQGAAAAVQLLVTLSFLSSLVKTQVTGVLDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGRSNKYSQAANSTKELDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRELQNFKALLQHRR
What is the function of this protein?
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum.  Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation.  Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2, PDIA3, PDIA4, PDIA6 and NXNDC12.  Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell (By similarity).  Involved in oxidative proinsulin folding in pancreatic cells, hence required for glucose homeostasis in vivo.
What are the official names of this protein?
ERO1-like protein beta, ERO1-L-beta, Endoplasmic reticulum oxidoreductase beta, Endoplasmic reticulum oxidoreductin-1-like protein B, Oxidoreductin-1-L-beta.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=The association with ERP44 may be essential for its retention in the endoplasmic reticulum.
Protein: RL10_THIDA
Sequence: MSLNLEEKKAVVAEVAAQVAAAQTVVVAEYRGIAVEDMTQLRVKARKEGVYLRVLKNTLVRRAVADTPFAGIADQLVGPLAYGISKDPVAAAKVMHEFSKTNDKFVVKAGAMPNFLMSPKDVGNLASMPSREELLSKLLGTMQAPIAQFVRTLNEVPTKFVRGLAAVRDKQAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CAT_ACIBA
Sequence: MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFLKTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETFSSLWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNVANMDNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGGA
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: GGCT_HUMAN
Sequence: MANSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDEQEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIEDIIKKGETQTL
What is the function of this protein?
Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (PubMed:18515354).  Induces release of cytochrome c from mitochondria with resultant induction of apoptosis (PubMed:16765912).
What are the official names of this protein?
Gamma-glutamylcyclotransferase, Cytochrome c-releasing factor 21.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: LACA_STAAE
Sequence: MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDATLAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMITMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RL34_ARTS2
Sequence: MSKRTFQPNNRRRAKKHGFRLRMRTRAGRAILAARRGKGRTELSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NUDC_YERP3
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGATARQIGEWQGQPVWLIRQMMPSGMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRFCGYCGHEMHASRTEWASLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMADYDSGELCHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREHSDLSQ
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: CTSR_STAA8
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: SECA_ECOSE
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS11_JANMA
Sequence: MAKAPNNAAAARVRKKVKKNVAEGIAHVHASFNNTIITITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAEAAGKVAIECGIKNLEVRIKGPGPGRESAVRALNNLGIKITQIQDVTPVPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: YYBO_BACSU
Sequence: MTEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSLLDRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNVIGAPLVAFLVTTFDWRVAFLTIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNRKVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYRTVIIVGMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFDVTGSFTLSFLVAGFVLLLGLVFYVFVLGDVKRIKL
What are the official names of this protein?
Uncharacterized transporter YybO.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHLB_SALDC
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKRFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_CAMJE
Sequence: MPKTQTLEQTKLSEPKMYKVILLNDDVTTMDFVIEILMNIFHQNLEKASQTMLEIHHNGSGICGIYTQEIALSKQKKVMDAAKLANFPLQAKVEEE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: METK_STRS7
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSPDIAQGVNEALEAREGQSDDFNVIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLAALRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQVIKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSESILEAAVRQVFDLRPAGIIKMLDLKRPIYKQTAAYGHMGRTDIDLPWEHLDKVSPLTEAVAALSEGA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y034_CHLMU
Sequence: MLEKLIKNFVAYMGVASELELDADGSYVLPISDLVRMRVRQNADEEIIISAFLGEIPASMDIEKAYARMMEGNLFGHETGGAALGLDSDGHAVLVRRVPGEVSQEDFANYIESVLNHAEAWLEDLGLSKMEQE
What are the official names of this protein?
Uncharacterized protein TC_0034.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0713/CT_663/TC_0034 family.
Protein: CYB_MICLI
Sequence: MTIIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLAIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLALMPLLHTSKQRALTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFTIIMILMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRIM2_HUMAN
Sequence: MASEGTNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
What is the function of this protein?
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11.  Plays a neuroprotective function.  May play a role in neuronal rapid ischemic tolerance.  Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity (PubMed:24068738).
What are the official names of this protein?
Tripartite motif-containing protein 2, E3 ubiquitin-protein ligase TRIM2, RING finger protein 86, RING-type E3 ubiquitin transferase TRIM2.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_ALBFT
Sequence: MADQLIIFDTTLRDGEQSPGASMNKDEKLRIARQLERLKVDVIEAGFAASSNGDFEAVQGIARAIKDSTICSLSRANDRDISRAAEALKGANRSRIHTFIATSALHMEKKLRMTPDQVFEQAKLAVRFARNLVADVEFSPEDAYRSDEDFLCRVIEAAINEGATTINVPDTVGYAIPELYGTFIKTLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNCSLEEVVMAVKTRRDYFGLDVDIETQHILAASRMVSQITGFVVQPNKAIVGANAFAHAAGIHQDGVLKARDTYEIMRAEDVGWSANKIVLSKVSGRNAFKQRLQDLGAQMESESDVNAAFARFKELADRKSEIFDEDILALVGSESVAREKEQYSFVSLSQHSETGERPQASIVFTADGKEVKSSSDGDGPVDASLKAIEAQVKSGAEMVLYSVNAISGSTESQGEVTVRLQHGGRVVNGVGADPDIIVASAKAYLSALSKLHSKADRVAAQG
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: DNAK_GEOUR
Sequence: MSKVIGIDLGTTNSCVAIMEGGEPIVIANAEGSRTTPSMVAITDSGERLVGQQAKRQAVTNPENTLFAIKRLIGRKFDSEAVKKDIAISPFKIVKADNGDAWVEVRGQKYSAPEISAMVLQKMKKTAEDYLGETVTDAVITVPAYFDDSQRQATKDAGKIAGLNVLRIINEPTAAALAYGLDKKKDEKIAVFDLGGGTFDISILELGEGVFEVKSTNGDTFLGGEDFDQDIIDWIAAEFKKDQGIDLRGDKMALQRLKEAAEKAKCELSTSLETDINLPFITADATGPKHLNLKLTRAKLEAICANLIAKLEGPCRTALKDAGLSPNDIDEVILVGGMTRMPIVQKKVQDIFGKVPNRSVNPDEVVAIGAAIQGGVLRGDVKDVLLLDVTPLSLGIETLGGVMTRLIEKNATIPCRKSQIFSTAADNQPAVSIHVLQGEREMSTDNKTLGNFELSGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQSIRITASSGLSKEEIDKMVKDAEAHSSEDKKKRELIEARNQADSLAYSTEKSLKEFGDKIDAAEKQKIEDGLAALKKAMEGSDADAIKKASDELMQASHKLAEAVYAKAQPGEEQAGGAPHEGEAKDEKVVDADFEEVKEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DCD_HAMD5
Sequence: MRLCDHDIERWLDEKKLTITPRPPAKHINGATVDIRLGHEFRVFVGHKAPFIDLSAPKEEINHALDQIMSDKIVLKEKECFFLHPGELALAVTLESVTIPDDLVGWLDGRSSLARLGLMVHVTAHRIDPGWRGQIVLEFYNSGKLPLGLRPGMLIGALSFELLSGQAKRPYHQRQDAKYHNQKGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CHED_BORPE
Sequence: MPARLDARATRRYFDNAFNSPAVKILPNEYYVTNGEDVMLSTVLGSCVAACIHDPVIGVGGMNHFMLPEGDIHSPASATMRYGAFAMEVLINELLKAGAVRERLEAKVFGGGAVLSAMQLMNIGERNGQFVLNYLKTEGIPVRAQDLGDVHARRINYFPRDGRVMVRKMAPHHQKAEALIAQREAAAAQTVQAETRAAPRVERFDTPSRRDPVGA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: RLMH_UREPA
Sequence: MMIKIISVGKLKQKAFVDLINDYLKRINHYLKCQEIVVSDEPEPVQISNKSLEQIKSKEASKIFKNINQNDFVIALIIESNIISSETLAKKIQQWLNTFSHDICFIIGGSNGLHESIYERANYHLSMSKMTFAHGLAKVMLCEQIYRALSILNNGKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_ACIET
Sequence: MPELPEVEVTRRSFAGAIEGATVRGITVGKPLRWPLGTEPAVLVGRRVCGVRRRGKYLLLDLDEGLLLIHLGMSGSLRFARDLPARGAHDHFELITDHGTLRLHDPRRFGAVVWAAGESDPRARKLLDGWGLEPLGEDFAFEAFHAGLRAKRTPIKQLLLAGTVVVGVGNIYACEVLFLAGIRPTTRACAIGPQRARRLHGAIREVLARAVERGGSTLRDFSSADGSAGHFQLEANVYGRAGLQCRQCGTPVRLSRQGQRSTYFCPHCQRA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TOLB_XYLFA
Sequence: MTKFPRWLAMLVGLLFPLSALTQQQGLTIDIVGGNTAATPIAVLPMPYHDSVGAPATDVSSVVAADLNRSGQFRTLPLGQIIERPTHGSEIRFPTWQALKQDYIVVGRVLDARQGTYRVEYELFDVRNGKRMLGLAMTARASAMRDVAHQMADAIYEKITGLRGAFFTRIAYVTASGSHGAMRYALMVADSDGYNPQTIVRSAEPLLSPDWSPDGKKLAYVSFEKGGSSIYIQDIATGSRELVSSFRGINAAPSFAPDGHRIALSLSRSGNPEIYVMDLVSKQLIQLTNSFGIDTEPAWSSDGKFIYFTSDRGGRPQIYKVASVGGTATRVTFQGNYNATTSVSYDDKKIVVAQGSGNVYRIAMMDQSSGSTVWNTLSTGSLDESPSFAPNASMVLYAAREGGRGVLYAVSADARVRQRLVSVDSDVREPAWGPYRSVH
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y388_LISIN
Sequence: MGRKWANIKEKKASKDKTNSRIYAKFGIEIYVAAKSGDPDPHSNQKLRFVIERAKTYNVPKHIIDRAIEKAKGTGDETYSELRYEGFGPNGSMIIVDALTNNVNRTASDVRAAYSKNGGNMGVSGSVAYMFDNTAIFGVEGKDADELLELLMEADIDVRDILDEDGQAIIYAEPEDFHKVQEGLKAAGIEEFTVAEIEMIPQNDIQLSGEDLEKFEKLIDALEDLEDVQKVYHNVELED
What are the official names of this protein?
Probable transcriptional regulatory protein lin0388.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_DEIDV
Sequence: MSVVILDFGSQFTRLIARRFRELGAYSVILPGTASLERIGQENPQGIVLSGGPSSVYDERAPRPAPGVLELDVPILGVCYGMQFLAHEAGGDVKRAGKREYGKADLTRYGGQLFEGIQGEFVAWMSHSDSVTQLPAGYEVVAETEDTPVTAIENPVSRRYGVQFHPEVVHTPKGGQLLANFLKICDVKRDWTAAHIVEELIADVQHQVGDSGRVLLGISGGVDSSTLALLLARAVGERLTAVFIDHGLLRLGEREQVEAALRPLGVNLVTVDAREEFLGSLRGVSDPEQKRKIIGREFIRAFERETAKLGDFDFLAQGTLYPDVIESAGGHHGDKSGAANIKSHHNVGGLPEDLKFKLVEPFRTLFKDEVREIAQLLGLPDHIRMRHPFPGPGLAIRCLGEVTEEKLEILKRVDDIFISGLREFGLYDGCSQALAVLTPIQSVGVMGDERTYSYTVALRAVTTDDYMTAEWARLPYEFLATMSNRIVNQVHEVNRVVYDITGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RS3A_THEAC
Sequence: MAGEKAQKKGKEKWKEKTWYTVESPPYLGSKEVTVALGEDPESMVNRIVEVPISDLTGNFKKSNEKALFRITGCEGTKCKTIFIGHYIGDDYIRRLVRRRKERIDIIEDVKTSDGSIITVKIVVVSDGKLTNTKKSEIRKALTSFIVSKGSQLSYADFVRYLIGDDSYNDMVEATKNIYPLRKIEIRKSELVSLSGMQEPQKNEPAPGGEAIAQN
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.