PharMolix/UniProtQA huggingface dataset:
Protein: IDH_AZOVI
Sequence: MSTPKIIYTLTDEAPALATYSLLPIIKAFTGSSGIAVETRDISLAGRLIATFPEYLTDTQKISDDLAELGKLATTPDANIIKLPNISASVPQLKAAIKELQQQGYKLPDYPEEPKTDTEKDVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWSADSKSHVAHMDNGDFYGSEKAALIGAPGSVKIELIAKDGSSTVLKAKTSVQAGEIIDSSVMSKNALRNFIAAEIEDAKKQGVLLSVHLKATMMKVSDPIMFGQIVSEFYKDALTKHAEVLKQIGFDVNNGIGDLYARIKTLPEAKQKEIEADIQAVYAQRPQLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGPDGKLHDTKAVIPDRCYAGVYQVVIEDCKQHGAFDPTTMGSVPNVGLMAQKAEEYGSHDKTFQIPADGVVRVTDESGKLLLEQSVEAGDIWRMCQAKDAPIQDWVKLAVNRARATNTPAVFWLDPARAHDAQVIAKVERYLKDYDTSGLDIRILSPVEATRFSLARIREGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFETGAGGSAPKHVQQFLEEGYLRWDSLGEFLALAASLEHLGNAYKNPKALVLASTLDQATGKILDNNKSPARKVGEIDNRGSHFYLALYWAQALAAQTEDKELQAQFTGIAKALTDNETKIVGELAAAQGKPVDIAGYYHPNTDLTSKAIRPSATFNAALAPLA
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the monomeric-type IDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_MACCJ
Sequence: MKNIGILGASGSVGTQGLDIIRQYPDTYKLVSFSVGKNLELANKIIEEFRPDICCVQDKEDIDKIQSSSIKVVYGNDGLMEIAAYVKNDMLLNSIMGSIGLKPTVHAIKHGIDIALANKETLVVAGEIIMQLAREYNVNIIPVDSEHSAIFQCLNGEDHKHIEKLIITASGGSFRELSREALKDVTVQDALKHPNWSMGKKITIDSATMMNKGLEVIEARWLFDMPIDKIETLLHKQSIIHSMVEFNDTSVIAQLGTPDMRMPILYAFSYPDRLARKAERLNLAEVGQLDFKAMDFDRYRCLKLAYDAISIGGTMPVVMNAVNEVVVQQFLDGEIGFLDIETIIEREMNAHDVIQSPDLETILEIDAQYKSRKYEV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: NU6M_CHOCR
Sequence: MNIDIFLFYLFSIFALISSLMVIGLTNAVHSVLFLILVFCNVAGLLLLLGPEFFSFMLIIVYVGAIAVLFLFVVMMLNIKLKSTNISFSSLWPIGILTFVILLSQFFSSFYELDLVKFQGKELFFISWANENSNLTNIKVIGKVLYTHFNLLFLICGLILLVAMIGVIVLTMHQRVDVKKQQIALQLARTAPNVIKFIILRRKR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: UVSE_BACC4
Sequence: MLIRFGYVSHAMALWDCSPAKTMTFTSFKKLSKQEREDKLYHVIRQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGVFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKILDAIGIADSSYINIHVGGAYGNKEKAIERFHENIKKLPTHIKKQMTLENDDKTYTTAETLSICQKENIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNISPKVHISSPRSEKEFRAHAEYIDLEFIKPFLHIAKKHNHNFDIMIESKQKDLALFQLIDELSAIRGIKRISGAMLQW
What is the function of this protein?
Component in a DNA repair pathway.  Removal of UV LIGHT damaged nucleotides.  Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity).
What are the official names of this protein?
UV DNA damage endonuclease, UV-endonuclease, UVED.
What is the protein family that this protein belongs to?
Belongs to the uve1/UvsE family.
Protein: SPAT2_RAT
Sequence: MDTKYKDDLFRKYVQFHEGKVDTTPGKQSGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILKFMGYEPELGTAYKLKELVESLQVKMVSFELFLAKVECEQMLGIHSQVKDKGYSELDVVTERKSSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLTMSSSPHGSPDDLPSISPINGLGLLRSTYFPTQDDVDLYTDSEPRATYRRQDALRSDIWLVKNDAHSIYHKRSPPTKESALSKCQNCGLSCSSSLCQRCDSVCPSASKPSGFPSKASAHDSLVHGAPMREKYVGQTQGLDRLATVHSKPKPSTTATSRCGFCNRAGATNTCTQCSKVSCDPCLGAYHYDPCCRKSELHKFMPNNQLNYKSTQFSHPVYR
What is the function of this protein?
Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis.  Acts as a direct binding intermediate that bridges RNF31/HOIP, the catalytic subunit of the LUBAC complex, and the deubiquitinase (CYLD), thereby recruiting CYLD to the TNF-R1 signaling complex (TNF-RSC).  Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of CYLD (By similarity).  Controls the kinase activity of RIPK1 and TNF-alpha-induced necroptosis by promoting 'Met-1'-linked deubiquitination of RIPK1 by CYLD (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the SPATA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: POLG_HCVE1
Sequence: RNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTVPASAYQVRNSSGLYHVTNDCPNSSIVYEAADAILHTPGCVPCVHEGNVSRCWVAMTPTVATRDGKLPTTQLRRHIDLLVGSATLCSALYVGDLCGSVFLVGQLFTFSPRRHWTTQGCNCSI
What is the function of this protein?
Forms a heterodimer with envelope glycoprotein E2, which mediates virus attachment to the host cell, virion internalization through clathrin-dependent endocytosis and fusion with host membrane (By similarity).  Fusion with the host cell is most likely mediated by both E1 and E2, through conformational rearrangements of the heterodimer required for fusion rather than a classical class II fusion mechanism (By similarity).  E1/E2 heterodimer binds host apolipoproteins such as APOB and ApoE thereby forming a lipo-viro-particle (LVP) (By similarity).  APOE associated to the LVP allows the initial virus attachment to cell surface receptors such as the heparan sulfate proteoglycans (HSPGs), syndecan-1 (SDC1), syndecan-1 (SDC2), the low-density lipoprotein receptor (LDLR) and scavenger receptor class B type I (SCARB1) (By similarity).  The cholesterol transfer activity of SCARB1 allows E2 exposure and binding of E2 to SCARB1 and the tetraspanin CD81 (By similarity).  E1/E2 heterodimer binding on CD81 activates the epithelial growth factor receptor (EGFR) signaling pathway (By similarity).  Diffusion of the complex E1-E2-EGFR-SCARB1-CD81 to the cell lateral membrane allows further interaction with Claudin 1 (CLDN1) and occludin (OCLN) to finally trigger HCV entry (By similarity).
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hepacivirus polyprotein family.
What are the subcellular locations of this protein?
[Core protein precursor]: Host endoplasmic reticulum membrane; Single-pass membrane protein. Host mitochondrion membrane; Single-pass type I membrane protein. Note=The C-terminal transmembrane domain of the core protein precursor contains an ER signal leading the nascent polyprotein to the ER membrane. SUBCELLULAR LOCATION: [Mature core protein]: Virion. Host cytoplasm. Host nucleus. Host lipid droplet. Note=Only a minor proportion of core protein is present in the nucleus (By similarity). Probably present on the surface of lipid droplets (By similarity). SUBCELLULAR LOCATION: [Envelope glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The C-terminal transmembrane domain acts as a signal sequence and forms a hairpin structure before cleavage by host signal peptidase (By similarity). After cleavage, the membrane sequence is retained at the C-terminus of the protein, serving as ER membrane anchor (By similarity). A reorientation of the second hydrophobic stretch occurs after cleavage producing a single reoriented transmembrane domain (By similarity). These events explain the final topology of the protein (By similarity).
Protein: RS9_SYNSC
Sequence: MSNNSVVYWGTGRRKTSVARVRLVPGNGTITINGRPGDNYLNYNPSYIAAVKAPLETLGLSSEYDILVNVHGGGLTGQSGAIKQGAARALCELSADNRKPLKTEGHLSRDPRAKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS6_HALHL
Sequence: MRHYEIVFMVHPDQSDQVPAMVERYRSIVESSGGTVHRLEDWGRRQLAYPINKLIKAHYVLMNVECGKDELDELTSAFRFNDAVIRNMVLSRDEAVTEPSPLAKGNEKREDRKESEDAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y1551_THEMA
Sequence: MIGEHPYVKWAIRVIENYVRYGKVIEPDESVPEELFKRRAGAFVTLHKTDGSLRGCIGTYLPTKPNLALEIRDNAIAAATQDPRFPPVSPDELDDIVVHVDILSPPEPVRDISELDPKKYGVIVVKGWRRGLLLPDIEGVDTVEEQLRIAKLKAGIPEWDDDVEIYRFTVERYK
What are the official names of this protein?
Protein TM_1551.
Protein: UPPP_KORVE
Sequence: MNAYLLAALLGVVEGLTEFLPVSSTAHLRICEALLHIDLGDGFWKMFSIVIQLGAILCLPIYFRARISEFFATFPKGKSGNHTALTHPLTLTIIAFLCTAIPAFLFTKIIGKHLESVIIMGSALLIGGIVMWIVDVMFADKGATDDMDKMSVGQAIWIGLCQVLSAVFPGTSRSMSTIAAGQLSGMTRAAALEFSFFLSIPTMVVATCYDLLKTLRHKDEAGAALGVVHMDAHAWITLAIGFIVSFIVAYFVVAWFMKWVRTRGFVPFAVYRIVVGIAVLAWALKR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_GALSU
Sequence: MSQSLEEKSVQERTRIKNSRYESGVIPYAKMGYWNPDYQVKDTDVLALFRVTPQPGVDPIEAAAAVAGESSTATWTVVWTDLLTAADLYRAKAYKVDQVPNNPEQYFAYIAYELDLFEEGSIANLTASIIGNVFGFKAVKALRLEDMRLPFAYIKTFQGPATGVILERERLDKFGRPLLGCTTKPKLGLSGKNYGRVVYEALKGGLDFVKDDENINSQPFMRWRERYLFVMEAVNKAAAATGEVKGHYLNVTAATMEEMYARAQLAKELGSVIIMIDLVIGYTAIQTMAKWARDNDMILHLHRAGNSTYSRQKNHGMNFRVICKWMRMAGVDHIHAGTVVGKLEGDPIITRGFYKTLLLPKLERNLQEGLFFDMDWASLRKVMPVASGGIHAGQMHQLIHYLGEDVVLQFGGGTIGHPDGIQSGATANRVALEAMILARNENRDFLTEGPEILREAAKNCGALRTALDLWKDITFNYTSTDTSDFVETPTANI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (Probable).  Carbon dioxide and oxygen bind in the same pocket of the enzyme in a similar manner (PubMed:23112176).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GUAC_ALIF1
Sequence: MRIEQELKLGFKDVLFRPKRSTLKSRSQVELTRDFTFKHSGRQWSGTPVIAANMDSVGSFAMAKALSEHGVMTAVHKHYTVADWAEFIKENDASVLKNAMVSTGTSEADFQKTKDIMALTDDLIFICIDIANGYSEHLVQYVEKVRAEFPDKVISAGNVVTGDMVEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECADAAHGLGGRIIGDGGCSCAGDVSKAFGGGADFVMLGGMLAGHEESGGEVIEQDGKTFMKFYGMSSQSAMDKHSGGVAKYRAAEGKTVLLPFRGSVHNTISDILGGVRSTCTYVGAAKLKELTKRTTFIRVQEQENNVFGKE
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: ICMT_DICDI
Sequence: MDQSEIVKLNKIKAKSAWLKKGAARSSAISCGLGIGIGFGIALFIFSQTLRGFGIYLAGLCTFHMWEYIWVTMYHPDKLSSKSFLLNHSPQFNMALLISFIEFWIEWYFFPSLKTFSLWWVGAICMVFGQIVRSVAMDTAGSNFTHLVQEEKRDDHVLVTNGIYQYMRHPSYFGWFVWSVSTQVILMNPISIIGFGWASWSFFSQRIENEEDYLIQFFGKSYKDYKKSVWSGIPGIH
What is the function of this protein?
Methylates the C-terminal cysteine residues of small GTPases and the heterotrimeric G protein gamma subunit in response to cAMP.  The methylation is required for intercellular signaling and regulation of cAMP waves propagation.  It also seems to induce the activity of car1, a G protein-coupled receptor which senses extracellular cAMP during the aggregation phase of development.
What are the official names of this protein?
Protein-S-isoprenylcysteine O-methyltransferase, Isoprenylcysteine carboxylmethyltransferase, Prenylated protein carboxyl methyltransferase, PPMT, Prenylcysteine carboxyl methyltransferase, pcCMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SURE_ANASK
Sequence: MRVLLSNDDGVHAAGLKALADAFHGDEVWVVAPDREQSASSHAISLHRPLRLLEVAPRWYAVDGTPTDAVYMGLNLVLRDARPDVVVSGVNHGPNLGNDVLYSGTVAAAMEGALLGVNAVAVSLAAPPPHDFGEAARFAAALARQVVARPPPAPVLLNVNVPPGPVRGYRFARLGRRTYGNEVVEKTDPRGRKYYWIGGEGRVHNEDIPGSDCNTVLLERLAAVTPLHLDGTHDPMFQELRSWTVPGYEKEPAP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_PSESM
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQADVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYTGQGLYEPLDLQIAKCRLMTAGAIGAVEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLIGLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHARIQALIDTLRKAVESRHRC
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SYNS9
Sequence: MPPFSHVPVLADAVVAGAEHLPHHNGVLIDATLGGGGHSALLLERFPGLRLIGLDQDPTARAAAAERLAAFADRVEILATNFASYTPPAPVLMVLADLGVSSPQLDVAERGFSFRLDGPLDMRMNPGSDGETAAELIDRLEENALADLIYGYGEERLSRRIARRIKADLAAQGPYEGTAALAYAVAGCYPPKARRGRIHPATRTFQALRIAVNDELAVLDRLLQQAPDWLETGGVMGVISFHSLEDRRVKTAFLQDERLERITRKPTVATDDEQNRNPRSRSAKWRLARRVNGC
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_CHLPB
Sequence: MNFPDDLRYTSDHEWVKVLDDGKVRVGITDFAQSELGDIVFVETKPVGTVLKQQDIFGTVEAVKTVADLFAPVTGKINAVNDALDAAEIVNSSPYDEGWMIEIIVDDPEQVNALMTVQEYKKTVGE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HIS4_SHESH
Sequence: MIIPAIDLIEGQVVRLYQGDYAQKTTFDLSPLSQLKSYEAQGANWLHIVDLTGAKDPNARQTRLIAGLVSGLDANIQVGGGIRTEAQLAELLEIGVKRVVIGSLAVKETALVQSWFKKYGADAICLALDVNINEQGEKIVAVSGWQSGGGKSLESLVDAFKPYGLKHALVTDISRDGTLKGANTDLYREIAAAYPDINWQASGGIATLDDVAAVRDSGADGIIIGKALLIENFTVREAIQCWPNPQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_SFSV
Sequence: MDEYQKIAVEFGEQAIDETVIQDWLQAFAYQGFDARTIIHNLVQLGGKSWEEDAKKMIILSLTRGNKPKKMVERMSPEGAREVKSLVAKYKIVEGRPGRNGITLSRVLQPWLGGQSKLWKWLKTSYQSQGAQWTALCGQTYPRQMMHPSFAGLIDPSLDQEDFNAVLDAHKLFLFMFSKTINVSLRGAQKRDIEESFSQPMLAAINSSFIDNTQRRAFLTKFGILTSGARATAVVKKIAEVYRKLE
What is the function of this protein?
Encapsidates the genomic RNA, protecting it from nucleases.  Displays high affinity for single-stranded nucleic acid.  The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein.  The ribonucleoprotein has a non-helical structure (By similarity).  Serves as template for viral transcription and replication.  After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus.
Protein: GLK_ECOLU
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM11A_HUMAN
Sequence: MMYRTVGFGTRSRNLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEYYHGSFKILDPQINNNFGQSNTYQLKDLRETTENLVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVIMVFQFPSTEQRAVREKKIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRRICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTGI
What is the function of this protein?
Probable serine protease which may play a role in cellular senescence.  Overexpression inhibits cell growth and induce G1 cell cycle arrest.
What are the official names of this protein?
Transmembrane protease serine 11A, Airway trypsin-like protease 1, Epidermal type-II transmembrane serine protease, Esophageal cancer-susceptibility gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL2_SHISS
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TAM_SHIF8
Sequence: MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRITYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLTRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MN1_HUMAN
Sequence: MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKEAHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT
What is the function of this protein?
Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate.  Required during later stages of palate development for growth and medial fusion of the palatal shelves.  Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL.  Necessary for normal development of the membranous bones of the skull (By similarity).  May play a role in tumor suppression (Probable).
What are the official names of this protein?
Transcriptional activator MN1, Probable tumor suppressor protein MN1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCSB_STAAS
Sequence: MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYATENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDESLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLTLGKSELEIIETLTEVVNQIIHEEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITMEEASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHIK
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.