PharMolix/UniProtQA huggingface dataset:
Protein: MENB_PASMU
Sequence: MQNPKDDVLYAPIEWQDHSEGYTDILYHKSLDGIAKITINRPEVRNAFRPQTVKEMIQAFADARFDEQIGVIVLTGQGEKAFCSGGDQKVRGDYGGYQDESGVHHLNVLDFQRDIRTCPKPVVAMVAGYAIGGGHVLHMICDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKEALEMGLVNTVVPYAELEKETVRWCREMLRNSPIALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNEKRAPDFSKFKRNP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: CYB_NAPIN
Sequence: MINIRKKHPLMKILNESFIDLPTPCNISSWWNFGSFLGACLAIQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYTFIETWNIGILLLSAVMATAFMGYVLPWGQMSFWGATVITNLLSAILYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLISDADKIPFHPHYTIKDALGFLLMSLFLLSLVLFSPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILILAIVPFLHNANQRSMIFRPLSQCLYWALVAGLITLTWIGGQPVEHPFIIIGQVASILYFLIILILMPLASFLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURA_FUSNN
Sequence: MVEAFKIIGGKKIAGELKVDGSKNSTLPIMIATLVEKGTYVLRNVPDLRDIRTLVALLESLGLEVEKLDANSYKIINNGLSGAEASYDLVKKMRASFLVMGGMLAIEKRGKVALPGGCAIGARPVDLHLKGFEALGAKINIEHGYVEATTENGLIGGNIVLDFPSVGATENIIMAAVKAKGKTVLENAAKEPEIEDLCNFLIKMGAKISGVGTSRLEIDGVDKLTACEYTIIPDRIVAGTYIIASILFDGSIKVSGIVPEHLSSFLLKLEEMGTKFKIEGDKLEVLTKLSDLKPAKVTTMPHPGFPTDLQSPMMTLMCLVNGTSEIKETIFENRFMHVPELNRMGAKIEIDSSTAKITGVENFSSAEVMASDLRAGASLILAALKANGESLVNRIYHVDRGYENFEEKFKALGANIERIKTEA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_MYCTU
Sequence: MPDPATYRPAPGSIPVEPGVYRFRDQHGRVIYVGKAKSLRSRLTSYFADVASLAPRTRQLVTTAAKVEWTVVGTEVEALQLEYTWIKEFDPRFNVRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHRQIDRPCLLGYIDKCSAPCIGRVDAAQHRQIVADFCDFLSGKTDRFARALEQQMNAAAEQLDFERAARLRDDLSALKRAMEKQAVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWIVEKPGEPGDSGIQLVEQFLTQFYGDQAALDDAADESANPVPREVLVPCLPSNAEELASWLSGLRGSRVVLRVPRRGDKRALAETVHRNAEDALQQHKLKRASDFNARSAALQSIQDSLGLADAPLRIECVDVSHVQGTDVVGSLVVFEDGLPRKSDYRHFGIREAAGQGRSDDVACIAEVTRRRFLRHLRDQSDPDLLSPERKSRRFAYPPNLYVVDGGAPQVNAASAVIDELGVTDVAVIGLAKRLEEVWVPSEPDPIIMPRNSEGLYLLQRVRDEAHRFAITYHRSKRSTRMTASALDSVPGLGEHRRKALVTHFGSIARLKEATVDEITAVPGIGVATATAVHDALRPDSSGAAR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB5_XENTR
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFNEEAEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Tubulin beta-5 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CHIP_CHICK
Sequence: MKGKEEREREGGGGAVGPGAAGPGAGGGSPEKSHSAQEHKEQGNRLFGGRKYPEAAAAYGRAINRNPLVAVYYTNRALCYLKMQQHDKALADCKRALELDGQSVKAHFFLGQCQMEMENYDEAIANLQRAYNLAKEQRLNFGDDIPSALRIAKKKRWNSIEEKRINQENELHSYLTRLIMAEKERELAECRKAQQEENVDESRGRVQLAGIEAKHDKYLADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQDQLIPNLAMKEVIDAFISENGWVEDY
What is the function of this protein?
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation (By similarity).  Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase CHIP, RING-type E3 ubiquitin transferase CHIP, STIP1 homology and U box-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEB_ECOLI
Sequence: MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSKDIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALPVFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGSQGEAMAKKLAKGIEVKPGEIVIPFTD
What are the official names of this protein?
Uncharacterized lipoprotein YceB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: THIS_THET2
Sequence: MVWLNGEPRPLEGKTLKEVLEEMGVELKGVAVLLNEEAFLGLEVPDRPLRDGDVVEVVALMQGG
What is the function of this protein?
Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.
What are the official names of this protein?
Sulfur carrier protein ThiS, Thiamine biosynthesis protein ThiS.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein ThiS family.
Protein: PSAC_PROM9
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAAQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETSRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: APOC1_ACIJB
Sequence: MRLILCLPVLVVVLLMVLEGPAPAQGAPAIASTFRNIPNSLKEFGNNLKDAFESIPEATQKLMTSFAEGLKNFRIPMV
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_META3
Sequence: MGKKDKRWVMQRKNDFYYKLAKQNHYRSRASYKLLQLNEKFEIIYEGDNVVDLGCAPGGWLQASYDLVGEDGFVIGVDLQKVKPLREENIVAIQGDMTKKETINKIIDLMPSKADVVICDASPNISGVWEVDHSRSIELSLMALIATTHLLRKNGNFVVKVFQGSLFDQYVQLLTKYFKKVQTTKPKASRSVSAEVYVIGKKFLGKKFDKNTDFPIIKLIEDNEFLDRYIEETHEKKEGNETSDNDEDNNKNGLMIKKIKELRGKRSKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETC50_ENTFC
Sequence: TTKNYGNGVCNSVNWCQCGNVWASCNLATGCAAWLCKLA
What is the function of this protein?
Bacteriocin active against the Gram-negative bacteria C. jejuni, Y. enterocolitica and Y. pseudotuberculosis, and the Gram-positive bacteria S. aureus, S. epidermidis, L. monocytogenes and Listeria spp.  When added to the drinking water of chickens, causes a decrease in the levels of C. jejuni and S. enteritidis in the ceca, and in the levels of S. enteritidis in the liver and spleen.
What are the official names of this protein?
Bacteriocin E50-52.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIA/YGNGV family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYA_FRATF
Sequence: MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQQLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLDENGDIDYEQVAQLAKEHKPKMIIAGFSAFSGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVYVATTTTHKTLRGPRGGLILCNNNPELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVDYQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVANLLADVVFNCGDEKVENETAAKVLDLCDKLPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP2_YEAST
Sequence: MSTEPVSASDKYQKISQLEHILKRPDTYIGSVETQEQLQWIYDEETDCMIEKNVTIVPGLFKIFDEILVNAADNKVRDPSMKRIDVNIHAEEHTIEVKNDGKGIPIEIHNKENIYIPEMIFGHLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTEFILETADLNVGQKYVQKWENNMSICHPPKITSYKKGPSYTKVTFKPDLTRFGMKELDNDILGVMRRRVYDINGSVRDINVYLNGKSLKIRNFKNYVELYLKSLEKKRQLDNGEDGAAKSDIPTILYERINNRWEVAFAVSDISFQQISFVNSIATTMGGTHVNYITDQIVKKISEILKKKKKKSVKSFQIKNNMFIFINCLIENPAFTSQTKEQLTTRVKDFGSRCEIPLEYINKIMKTDLATRMFEIADANEENALKKSDGTRKSRITNYPKLEDANKAGTKEGYKCTLVLTEGDSALSLAVAGLAVVGRDYYGCYPLRGKMLNVREASADQILKNAEIQAIKKIMGLQHRKKYEDTKSLRYGHLMIMTDQDHDGSHIKGLIINFLESSFPGLLDIQGFLLEFITPIIKVSITKPTKNTIAFYNMPDYEKWREEESHKFTWKQKYYKGLGTSLAQEVREYFSNLDRHLKIFHSLQGNDKDYIDLAFSKKKADDRKEWLRQYEPGTVLDPTLKEIPISDFINKELILFSLADNIRSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTAYHHGEQSLAQTIIGLAQNFVGSNNIYLLLPNGAFGTRATGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQEDEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELEQMHPWFRGWTGTIEEIEPLRYRMYGRIEQIGDNVLEITELPARTWTSTIKEYLLLGLSGNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGFYERFKLISPISLMNMVAFDPHGKIKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGPEELYGTYEYLLGMRIWSLTKERYQKLLKQKQEKETELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEARGGNVPNKGSKTKGKGKRKLVDDEDYDPSKKNKKSTARKGKKIKLEDKNFERILLEQKLVTKSKAPTKIKKEKTPSVSETKTEEEENAPSSTSSSSIFDIKKEDKDEGELSKISNKFKKISTIFDKMGSTSATSKENTPEQDDVATKKNQTTAKKTAVKPKLAKKPVRKQQKVVELSGESDLEILDSYTDREDSNKDEDDAIPQRSRRQRSSRAASVPKKSYVETLELSDDSFIEDDEEENQGSDVSFNEED
What is the function of this protein?
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.  Topoisomerase II makes double-strand breaks.  Essential during mitosis and meiosis for proper segregation of daughter chromosomes.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_STAA1
Sequence: MNYQVLLYYKYTTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGINGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDDVDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPDITRFRDLPDWIKENKALFTDKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGQYWDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENETKYLGACSYECAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GCSPB_SULIM
Sequence: MVWRQAKWDEPLIFELNNSGANRQGLLINKDDEIRSEIKEMKIPKNLLRENGPNLPSLSELEVVRHFIRLSQMNFGVDVGIMPLGSCTMKYNPKIEEKATAITESHHPLEDEDHVQGILEMIYELQNWFSEITGMDECSLQVPAGSAGEFAGVLMIKKYHEDHNRNYKDTMLVADTAHGTNPASAAMAGYKVMYVKSNGEGLVDMDILREIVNDKTAGFMLTNPNTLGLFEENILEISKIIHSANAILYYDGANLNGVLGIARPGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGELVNYLPYPMVEKVNGKYRLSKIPKNSVGKIATFYGNVGNLARSFAYLLGLGPQGVQMVGKMSTLATNYLIAKLRDIKELELIAPNRHRKHEVVFSVKQLMENYGVSANDVAKALLDSGFYAPTIYFPPIIEEALMIEPTETESKETLDMFAEALKKIVEDAKRNPEQLLKSPSNTSIARLDQAYANHPSTITPTYRVLKLRRMGKINYLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: KNAT6_ARATH
Sequence: MDGMYNFHSAGDYSDKSVLMMSPESLMFPSDYQALLCSSAGENRVSDVFGSDELLSVAVSALSSEAASIAPEIRRNDDNVSLTVIKAKIACHPSYPRLLQAYIDCQKVGAPPEIACLLEEIQRESDVYKQEVVPSSCFGADPELDEFMETYCDILVKYKSDLARPFDEATCFLNKIEMQLRNLCTGVESARGVSEDGVISSDEELSGGDHEVAEDGRQRCEDRDLKDRLLRKFGSRISTLKLEFSKKKKKGKLPREARQALLDWWNLHYKWPYPTEGDKIALADATGLDQKQINNWFINQRKRHWKPSENMPFAMMDDSSGSFFTEE
What is the function of this protein?
Plays a role in meristem function.  Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner.  Involved in maintaining cells in an undifferentiated, meristematic state.  Probably binds to the DNA sequence 5'-TGAC-3'.
What are the official names of this protein?
Homeobox protein knotted-1-like 6, Protein KNAT6.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_HISS2
Sequence: MFYTENYDVIVIGGGHAGTEAALATARMKLKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDAMGGLMATAADKAGIQFRTLNSSKGPAVRATRAQADRVLYRQVVRIALENQPNLDIFQQEVTDIILEKDSIAGVETKMGLKFRAKSVVLTAGTFLAGKIHIGLENYAGGRAGDPASVNLAKKLRDLNLRVNRLKTGTPPRIDARTINFDILAKQYGDEKLPVFSFMGSVEQHPEQIPCYITHTNDQTHDVIRKNLDRSPMYTGVIEGIGPRYCPSIEDKVIRFSDRNSHQIYLEPEGLTSNEVYPNGISTSLPFDVQMKIVNSMKGLEKARIVKPGYAIEYDYFDPRDLKPTLETKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLFVQEKESWFPRRDQAYIGVLVDDLCTVGTKEPYRVFTSRAEYRLLLREDNADIRLTSIARELGLIDDIRWARFNQKMENIELERQRLRSIWLHPRSEYLNEANEILKSPLVREVNGEDLLRRPEINYQILTALTPFKPAMEDKEAVEQVEIAIKYQGYIEHQQEEIERQKRHENTAIPANFDYKNISGLSNEVCAKLEQYRPISIGQASRISGITPAAISILLVNLKKQGMLKRGE
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPE_STRCO
Sequence: MTTHAAEAPTTDPQGAPGSQKTPDATEAEEAARATVPHRAAAAALAREHDVVPLHQEFLDDSVSPVTAFAQLCGPDEAGFLLESVPVSGGVARYSYVGHRPVPLEPTGGDPLTALRSHLARSVAPVPGLPPFHGGVVGYLGYEAARHFEDLPLAAGPPPGLPESAFLAADDLVVFDHATRRVLLMTLYRPARESYDDAVARIVRLNRALRRAPAPAAFSGRPLAAATPADHGTQGWTANLTEAQFTERVARAREHIAAGDAFQIVLSRRLSRPLRARPTDLYRHLRATNPSPYMYHLSLGGGRHVIGASPELLVKAEGRTVRTRPLAGTRPRHPDPAEDLRLERELRADEKERAEHVMLVDLGRNDLGRVTEPGTVRVERLMRVERFSHVMHLSSTVRGRLAEGRDALDALRSAFPAGTLSGAPKIRAMEIIAELEPEQRGVYGGALGFVGADGLTDFAIALRTMVVADGHVHVQAGAGIVADSDPAAEFRETLHKSRAMLTAVRRAEAAA
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: UNC9_CAEEL
Sequence: MSMLLYYFASAVKSIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV
What is the function of this protein?
Structural component of gap junctions (PubMed:27015090, PubMed:33238150).  Plays a role in maintaining gap junction activity to promote locomotion (PubMed:33238150).
What are the official names of this protein?
Innexin unc-9, Uncoordinated protein 9.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Co-localizes with unc-1 at the gap junctions formed between PLM and other neurons.
Protein: KGUA_CALS4
Sequence: MSIKKQGLLIVISGPSGAGKGTICKALIEKEKDLKLSISATTRQPRAGEVDGKNYFFKSEEEFKRMIEEDAFLEWAKVYDHYYGTPKEFVLKNLEEGNDVVLEIDIQGALKVKEKFPEGVFIFILPPSMEELRNRIKKRGTESEEEIIKRFKSAYEELNYVSKYNYVVINDDVDRAVEKIRAIIIAEKCRVDRNKDLYLKIREESV
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBD25_ARATH
Sequence: MRNISDLPNDLLVKILSLIPIKVAASTSLLSKRWGSVWKLIPTLDYDGTYSAAALEFFGKFHTLVALRFMKLTIEDVHSTTCFRSVKNLSLLDVKFSSDKTVERLLSCFPILETLVVHRWGADNVKTFAICVPSLQSLNIRYTVGGYHNPKTDHGFVINAPSLKHLDIVDHFSGFCSLVNMPEQLDAEIHLRHIDSEKLLESLTSSKKLSLCLKPQTGSYPGGDFDQLVCLELCVMCSLDWLNLILRRSPKLRSLKLYQSRERNWSCRNSKHVRTKWEQPNSVPECLLVSLETVKWILYKGTQEEKDVVKYLLKNGNFIKTMSIRFSSVVTLEERIHIPMEFEFMGRINSSRCQLSFSKL
What are the official names of this protein?
Putative FBD-associated F-box protein At5g56430.
Protein: PEPQ_SODGM
Sequence: MESLSSLYRDHIATLQQRTREILQRQQLEGLLIHAGEPISRFLDDHDYPFKVNPQFKAWFPVTRVPHCWLWVDGVNKPKLWYYLSIDYWYLVEPLPDSFWTPYVDIVPFADPDEIAALLPPRDNVAYLGSSPHRASLLGMERDFINPQPVLDYLHYHRAYKTDYELACMREAQKSAVNGHRAAKEAFLSGMCEFDINIAYLSACGHRDTDVPYDNIIALNEHAAVLHYTRLDQHTPEHVMSFLIDAGTEYNGYAADLTRTYAAQKDSDFAALIAAMNSEQQALIATIETGVNYIDYHLQMHGRIAKLLKQFDILSGLSEDAMVTEGLTLPFLPHGLGHPLGLQVHDVAGFMQDDRGTSLAPQSRYTHLRCTRVLQPRMVLTIEPGLYFIESLLAPWRANTFGRHFNWSRIESFKPYGGIRIEDNIVIHDNHIENMTRALKLE
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: MABO2_PAENI
Sequence: MGRIGILGAGLAGLAAATKLAEAGENVTVFEARNRPGGRVWSETLDTPKGSYVIERGAEFVLDGYTSMRRLLSQFGLSLVDTGMSYYVREPGDTTGITCDDIIRTGREALELASGSGLQGTAEELLAKLPDEPELVDALRARIEISTAVSASEVTARSLQHIASFEPKPSWRVAGGNQRLPDAMAAALGSAVRYGETVRAVENISDGGVLVTTDTDTSVFDTVVVALPLAVIRDSQLNLPTTEARDAALKHVLQGHAAKLHLPLETQPATSAVMSVEGRYWTWTATDESGAVAPVLNAFMGSPSAITRANLKQRPAEWVAKARALRTDLAIPQDAAALTTVWSEDQLAGGAYAAHAPGVTAAGTALLEKPVGDVFWAGEYSEPEFVGLMEGAIRSGERAAGRVMQRLETKSGNSDSERSKA
What is the function of this protein?
Catalyzes the removal of methylamine from 4-methylaminobutanoate with the formation of succinate semialdehyde.  Is involved in the catabolism of 4-methylaminobutanoate produced from nicotine.  Has a very weak monoamine oxidase activity with 4-aminobutanoate.  Cannot use spermidine, spermine, sarcosine, dimethylglycine, glycine, choline, betaine, alpha-methylamino isobutyrate, methylamine propionitrile and methylamino propylamine as substrate.
What are the official names of this protein?
4-methylaminobutanoate oxidase (methylamine-forming), Gamma-N-methylaminobutyrate oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: TYSY_XANOM
Sequence: MKPYLDLLQHVLEHGAEKSDRTGTGTRSVFGWQMRFDLNDGFPLVTTKKLHLRSIIHELLWFLQGDTNIGYLSDNQVRIWDEWADDNGDLGPVYGKQWRRWTGPDGVEIDQMQWLVDEIKRNPDSRRLVISAWNVGELPQMALMPCHSLFQFYVVNGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQATGLGVGDFVHTLGDAHLYSNHFDQARKQLTRTPRALPTLRLNPEVTDLFAFRFEDIAIEGYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.