PharMolix/UniProtQA huggingface dataset:
Protein: ENO_SHIBS
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: 14334_ORYSJ
Sequence: MSPAEPTREESVYKAKLAEQAERYEEMVEYMERVARAAGGASGGEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEGRGNDAHAATIRSYRGKIEAELARICDGILALLDSHLVPSAGAAESKVFYLKMKGDYHRYLAEFKSGDERKQAAESTMNAYKAAQDIALADLAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAISELDSLGEESYKDSTLIMQLLRDNLTLWTSDANDDGGDEIKEAAAPKEPGDQ
What is the function of this protein?
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
What are the official names of this protein?
14-3-3-like protein GF14-D, G-box factor 14-3-3 homolog D.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: RS21_POLNA
Sequence: MTTIRVKDNEPFDVALRRFKRTIEKLGLLTDLRAREFYEKPTAERKRKKAAAVKRNYKRIRAMQLPKKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: GUNA_XANCP
Sequence: MSIFRTASTLALATALALAAGPAFSYSINNSRQIVDDSGKVVQLKGVNVFGFETGNHVMHGLWARNWKDMIVQMQGLGFNAVRLPFCPATLRSDTMPASIDYSRNADLQGLTSLQILDKVIAEFNARGMYVLLDHHTPDCAGISELWYTGSYTEAQWLADLRFVANRYKNVPYVLGLDLKNEPHGAATWGTGNAATDWNKAAERGSAAVLAVAPKWLIAVEGITDNPVCSTNGGIFWGGNLQPLACTPLNIPANRLLLAPHVYGPDVFVQSYFNDSNFPNNMPAIWERHFGQFAGTHALLLGEFGGKYGEGDARDKTWQDALVKYLRSKGINQGFYWSWNPNSGDTGGILRDDWTSVRQDKMTLLRTLWGTAGNTTPTPTPTPTPTPTPTPTPTPTPTPGTSTFSTKVIVDNSWNGGYCNRVQVTNTGTASGTWSIAVPVTGTVNNAWNATWSQSGSTLRASGVDFNRTLAAGATAEFGFCAAS
What are the official names of this protein?
Major extracellular endoglucanase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: EMC7_XENTR
Sequence: MPAVALGVSVGWRSLSLWLLALLQLCSADLDVLSPGSGSDKFKVEGRAVVPGVRPQDWVNTARVLVDGEEHVGFLRTDGSFVVHDVPSGSYVVEVISPAHRFEPVRVDITSKGKMRARYVNHIKTSEVVRLPYPLQMKSSGPPSYFIKRETWGWTDFLMNPMVMMMVLPLLIFVLLPKVVNTSDPEMRREMEQSMNMLNTNPELPDVSEFMTRLFTSKSSSKSSGSGKAGKSVGKRR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the EMC7 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: NU2C1_LEMMI
Sequence: MIWHVQNEVFILDSTRIFMKAFHLLLFNGSFILPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYIAMNLGTFARIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRKSPLRSNNSIELSMTVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HGD_XANOR
Sequence: MHNPQHYMTGFGNEFATEAVAGSLPVGQNSPQRVAHGLYAEQLSGTAFTAPRGENRRSWLYRIRPAAVHGRFSLIEQSRLHNDFGGGPVPPDQMRWSPLPLPATPTDFVDGLYTMAGNGSPEAMTGVAVHLYAANASMHGRFFYNADGELLLVPQLGRLRVCTELGVLELEPQQVGVIPRGVRFRVELLDSAARGYVCENFGGLLRLPDLGPIGANGLANPRDFETPRAAFEQRDGAFELVAKFQGDLWRADIDHSPLDVVAWHGNYAPYRYDLRRFNTIGSISFDHPDPSIFTVLTSPSDTHGTANMDFAIFPPRWLVAQHTFRPPWFHRNVASEFMGLVHGVYDAKAEGFAPGGASLHNCMSGHGPDAATFDKASQADLTRPDVIAETMAFMFETRAVLRPTQQALSAAHRQADYQQCWSGLRAAFQHPPAKNTTSVLR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: TMCAL_LIGS1
Sequence: MKIIGIIAEYNPFHNGHLYQIEKVKEIYPESIIIVAMSGNFLQRGEPAIVDKWVRAKQALLNGVDVVVEIPIAGCVQPADRFAENGVRILNNMGCEELFFGAEHAEYDFMTYAQLVQNLDSTEFSKKNISYAEAFQEAVAAKIGHNIDSPNDVLGLAYAKANLKFGKKLKLNPISRNVAGYHDKSLSPDSNIASATAIRKVLFSKDHNLVDKYLPSYQDLKDEKYISWDDFWPFLRYKLISSDIDELANIYGMAEGIQYRMKKKALELKVEATFDEWLKAVKSKRFTYTRLTRLSVATLVGMKVNDVSLYNKFPYVHLLGFTKNGQKALNIMKKNSEIPLLAKISQQDKDDFYHVDYRAGKIYQSQNYKEQDLKRAPLIF
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_HTL1L
Sequence: MGQIFPRSANPIPRPPRGLATHHWLNFLQAAYRLEPGPSSYDFHQLKTVLKMALETPVWMCPINYSLLASLLPKGYPGQVNEILQVLIQTQTQIPSHPAPPPPSSPTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGVPPTHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITGYNPLAGPLRVQANNPQQQGLRREYQQLWLTAFAALPGSAKDPSWASILQGLEEPYHTFVERLNVALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGHTNSPLGDMLRACQAWTPRDKTKVLVVQPKKPPPNQPCFRCGKAGHWSRDCAQPRPPPGPCPLCQDPTHWKRDCPRLKPAIPEPEPEEDALLLDLPADIPHPKNSIGGEV
What is the function of this protein?
Binds strongly to viral nucleic acids and promote their aggregation.  Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.
What are the official names of this protein?
Gag polyprotein, Pr53Gag.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-gag]: Virion.
Protein: YFEO_ECOLU
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQRLPGTLGIAQDSPFWIIAILTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALLGLIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGKMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVMGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRPKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAHH_ZYMMO
Sequence: MANEPYIVRDISLAGWGRKEIDIAEGEMPGLMALREEYAAKKPLKGARITGSLHMTIQTAVLIETLVDLGAEVRWASCNIFSTQDHAAAAIAEQNIPVFAVKGESLEEYWDYVDRIFDWGKGETANMILDDGGDATMFVLWGAKLEAGVEFPAPQNEEEEIFQKTVRRRVAATPGFLTKTAKAIKGVSEETTTGVHRLYEIAKKGELLFPAINVNDSVTKSKFDNLYGCKESLVDAIRRATDVMLAGKVACVAGFGDVGKGSAASLRNGGARVLVTEVDPICALQAAMEGYEVVTLEEAAPRADIFVTCTGNADIITLDHMRAMKQHAIVCNIGHFDSEIQINSLANMKWTEIKPQVDLVKFPDGKEIIVLAKGRLVNLGCATGHPSFVMSASFTNQVLAQIELFCNTDKYQKDVYMLPKHLDEKVAALHLPKLGVHLSKLTQKQADYIGVPVNGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ALTMD
Sequence: MARVTVEDAVDKIGNRFDLVLVAARRARQIATEGKDPMVDVQNDKPTVTALREIEEGLVTAATLEQADLQAQEQQEHAEFASVANILSDQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PSBZ_SELUN
Sequence: MTVALQSAVFASIAIPFIPVIGVPAVFASPDGWSSGKNVVFSGATPRIGPVPLVGILNSSVS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: FRS3_HUMAN
Sequence: MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL
What is the function of this protein?
Adapter protein that links FGF and NGF receptors to downstream signaling pathways.  Involved in the activation of MAP kinases.  Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
What are the official names of this protein?
Fibroblast growth factor receptor substrate 3, FGFR substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated neurotrophic factor target 2, SNT-2.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: TX104_LYCSI
Sequence: MKVLVVVALLVTLISYSSSEGIDDPEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEP1_PEDHE
Sequence: MKKQILYLIVLQQLFLCSAYAQQKKSGNIPYRVNVQADSAKQKAIIDNKWVAVGINKPYALQYDDKLRFNGKPSYRFELKAEDNSLEGYAAGETKGRTELSYSYATTNDFKKFPPSVYQNAQKLKTVYHYGKGICEQGSSRSYTFSVYIPSSFPDNATTIFAQWHGAPSRTLVATPEGEIKTLSIEEFLALYDRMIFKKNIAHDKVEKKDKDGKITYVAGKPNGWKVEQGGYPTLAFGFSKGYFYIKANSDRQWLTDKADRNNANPENSEVMKPYSSEYKTSTIAYKMPFAQFPKDCWITFDVAIDWTKYGKEANTILKPGKLDVMMTYTKNKKPQKAHIVNQQEILIGRNDDDGYYFKFGIYRVGNSTVPVTYNLSGYSETAR
What is the function of this protein?
Degrades heparin and heparan sulfate.  Also implicated in the release of heparin-bound growth factors from the extracellular matrix.
What are the official names of this protein?
Heparin lyase I, Heparinase I.
What are the subcellular locations of this protein?
Periplasm.
Protein: OTCC_STAAS
Sequence: MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVSMGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAA7E_MOUSE
Sequence: MATGDDSFLWDQDSILSRDLFSATSAELCYENLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSTVRSVEGCWYFGEIYCKLHTCFDVSFCSSSIFHLCFISVDRYIAVSDPLIYPTRFTASVSNKCITFSWLLSISYGFSLIYTGASEAGLEDLVSALTCVGGCQLAVNQSWVFINFLLFLIPTLVMITVYSKIFLIAKQQAQNIEKMSKQTARASDSYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSFIDAFLGFITPTYVYEILVWIAYYNSAMNPLIYAFFYPWFRKAIKLTVTGKILRENSSTTNLFPE
What is the function of this protein?
Orphan olfactory receptor specific for trace amines.
What are the official names of this protein?
Trace amine-associated receptor 7e, TaR-7e, Trace amine receptor 7e, mTaar7e.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SBSPO_HUMAN
Sequence: MRTLWMALCALSRLWPGAQAGCAEAGRCCPGRDPACFARGWRLDRVYGTCFCDQACRFTGDCCFDYDRACPARPCFVGEWSPWSGCADQCKPTTRVRRRSVQQEPQNGGAPCPPLEERAGCLEYSTPQGQDCGHTYVPAFITTSAFNKERTRQATSPHWSTHTEDAGYCMEFKTESLTPHCALENWPLTRWMQYLREGYTVCVDCQPPAMNSVSLRCSGDGLDSDGNQTLHWQAIGNPRCQGTWKKVRRVDQCSCPAVHSFIFI
What are the official names of this protein?
Somatomedin-B and thrombospondin type-1 domain-containing protein, RPE-spondin.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: S226B_XENLA
Sequence: MAFQEILESLGGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAATPSHHCRINGTYEETNFTGPWLRALLPMTPTGEFSKCLRYTTPQYELLENNLTQSYDDLETEPCLDGWVYDHSEFASTIITQWDLVCNHRRMRQVAQSIYMAGVLVGSILFGGLSDKFGRRPLNIWSNLQMFVTGICAAFSPNYIWYCIFRFLTGVAFSGIVLNSYSLTVEWIPTGNRAFTSTATGYCYTMGQLVLVGLAFIIRDWQWLQLAASIPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAQINGKKEAGEKLTVEILKSSMQREINASHNSTYSALDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFGTVDIPAKFISYFITTYVGRRVSQAITLILAGIAILVNISVPQDFQTVRTAMAVFGKGCLAASFNCLYLYTGELYPTVIRQTGMGLGAMMARLGGIIAPLAQMTGDIYHSLPLIIFGCLPILSGIAGCFLPETLGVPLPETIEEVESPDKQQKDVNVSAKIPLKETELYNMKTDV
What is the function of this protein?
Involved in the renal elimination of endogenous and exogenous organic anions.  Mediates the sodium-independent uptake of p-aminohippurate (PAH), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate.  PAH uptake is inhibited by furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 6-B, Organic cation transporter 1-B, Renal organic anion transporter 1-B, ROAT1-B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX42A_SCOMO
Sequence: MKAIYILSVLLLMMLPILSRFATSEGAAQHVEPIQKIRVEQNDCTRGIRCPRGHYCDPGLRQCLPR
What are the official names of this protein?
U-scoloptoxin(04)-Sm2a, U-SLPTX(04)-Sm2a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-04 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ROP1L_MOUSE
Sequence: MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELADLEKKWKNLCLPVEKLRTILELDPCEDKIEWIKFLALGCSSLGRTLNTAMKNVCEILTSDPEGGPARIPFETFAYVYQYLSGLDPELPAVETENYLTSLRLMSESRKNGMIGLSDFFVGKKII
What is the function of this protein?
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (PubMed:36417862).  Important for male fertility.  With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
What are the official names of this protein?
Ropporin-1-like protein, AKAP-associated sperm protein.
What is the protein family that this protein belongs to?
Belongs to the ropporin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cell projection, cilium.
Protein: RS8_STRA1
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIADILKREGFVKNVEVIEDDKQGIIRVFLKYGQNGERVITNLKRISKPGLRVYTKHEDMPKVLNGLGIAIVSTSEGLLTDKEARQKNVGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y3637_NITHX
Sequence: MLVRIPNVLTPEQVQHCREVMARTAWVDGRVTAGHQSAQVKRNLQLPEGTPEARELGDMVLAALNRNPLFVSAVLPKTIFPPLFNRYDADGEMNFGSHVDNAIRTVPGTGMRVRTDVSSTLFLSSPEEYDGGELVIEDTYGAHSVKLPAGDMIVYPGTSVHHVTKVTRGSRIASFFWTESMISDVIRRAMMFDLDMSIIRLNADHPEHPSVVSLTSLYHNLLRQWAQS
What are the official names of this protein?
PKHD-type hydroxylase Nham_3637.
Protein: COAX_NITEC
Sequence: MNVSSFLLAIDSGNTAIKWGLHTGDQWLVRGSALQSERMVLKQAWALLPAPPASVLISNVAGLQAADDLTALLKPWYVQPHWITASASQCGVTSRYTKPEQLGCDRWAALIAAWYRVQRACLVVDVGTAMTVDTLSSTGEFLGGIIVPGPDAMKQALAGCAGTLAAPVSSCFQNFPVNTENALYSGMIQALSGALERMYRLLSSYSEKQTLTEVIMTGGGAALLAQHIHIPHRIVDSLVLEGLAIIAKSGNFDYNKK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_CORGB
Sequence: MSSPSAPLATPDVELDVHTLSSENLPWLCIVWDDPVNLMSYVTYVFQTVLGFSKKRATELMMQVHTEGKAVVSSGEKDKVEGDVKKLHTAGLWATMQQAG
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: YCF72_SACOF
Sequence: MGAFPSPPPWGWSTGFITTPLTTGRLPSQHLDPALPKLFWFTPTLPTCPTVAKQFWDTKRTSPDGNLKVANLPSFAISFATAPAALANCPPLPRVISMLCMAVPKGISVEVDSSFLSKNPFPNCTSFFQSIRLSRCI
What are the official names of this protein?
Uncharacterized protein ycf72, ORF137.
What is the protein family that this protein belongs to?
Belongs to the ycf72 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RF1_STRPQ
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRIDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTKKLESLNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXA2A_TAKRU
Sequence: MNYEFERESGFINSQPSLAECLTSFPPVADSFQSSSIKSSTLSRPTLIPPPFEQTIPSLNPGSHPRHGRPRHSPDGCSPLPTASLPPEYPWMREKKASKRNHLPNSTTTTISNGPVCFSPKGSPEIVESAGGGGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQSKENHNAEGKGPSTEEGIHSDEEDEAPVFDRSGALLERDTCSFQKKSHGSAQQHHNSVSMGFAAAPLNSNDKNLKHFPNPSPTVPGCMSTIGPGSASGPDNSDSPPALDVSIHDFQPFSSDSCLQLSDAASPSLSESLDSPVDISTDSFYFFSESLTTIDLQHLSY
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A2a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFD_PSEAE
Sequence: MALPRPTSPHARGSNRTPAIMRLVLGACVPGLLTLTWLYGPGTLLNLAWASLVALACEAAMLALRKRPPGVFLKDGSALVTALLLAVALPPYAPWWLTLVATFFALVFGKHLYGGLGQNPFNPAMLGYVVALVSFPLEMTRWPSPDSALGLPDSLREFLGLATRPDAWAHATALDVLKTDRSLTVDELFAGNPAFGHLGSAGSEWVNLAFLLGGLFLLWRRLFTWHAPLGMLAGLFAMSLLFWNGSGSDSHGSPLFHLFSGATMLGAFFIVTDPVSGATSNRGRLVFGLGVGVLTYVIRAWGGYPDGVAFAVLLMNLAAPTIDYYTRPRTYGHRKAERGFKAGD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.