PharMolix/UniProtQA huggingface dataset:
Protein: SODM_HORVU
Sequence: VATFTLPDLPYDYGALEPAV
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GATB_NEIG2
Sequence: MTWETVIGLEIHVQLNTKSKIFSGASTAFGAEPNAHASVVECALPGVLPVMNREVVEKAIKLGLALDAKINRKNVFDRKNYFYPDLPKGYQISQLDLPIVEHGKLEIVVGGDVKTINVTRAHMEEDAGKSVHEGLNGATGIDLNRAGTPLLEVVSEPEMRSAAEAVAYAKALHSLVTWLDICDGNMAEGSFRIDANVSVRPKGQAEFGTRREIKNLNSFRFLDQAINYEAEAQIEILEDGGTVQQATMLFDPEKGETRVMRLKEDAHDYGYFPDPDLLPVIISDAQMQKAKAEMPELPKEMAARFVADYGVSEYDARLLTASRVQAAYFEEAAKESGQGKPTANWMNGELAATLNKEGMELADSPITAPRLAALVGKIADGTLSGKLAKKAFEAMWAEPETSIAEIIEKHSLQQMTDTGAVEAMVDEVLANNAKAVEQFKSGNEKALNAIVGQVMKTSKGKANPAQVQELIKAKLA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SYR_ARCFU
Sequence: MFLRFIEEVIKALGEYGDKKFLRESEHADLASTIAFKLAKERKKSPKEIADEIVENLEVESEYIGSVESVNGYINFFASYEFLEDTVNVILDEDENYGHLNLKGEILIEHTSANPDGPLHIGHIRNSIIGDTIARIFAKAGFDVKTHYYVNDMGRQTAITVLGIEKFGLKDKKPDHAVAEAYIEANKLLESNPELEEQVEKLMLAYEEGDEKTVEKFRRAVETALEGIKQTLKTINVEHDEFVWESEFVRNGYVGKVLGILEERGLVKKNGAWTIELEGFDKEVVLRRENGTTLYITRDLAYHMWKNENYERFINVLGADHKLYGAQLSKILELLGLKPPEIIFFEFVSLPEGSMSTRRGKFISADELISKVRDEAWKILSERDMEEDEKRKIADAVAVGAIRFDFIKIAPEKHMTFDWSKALDFERQTASYIQYSHARACSILRKAVEDGMPELEFKGELCTAGERKLVMLLSKMPYVVKRIVSELRPNVFAEYLLSVAGTFNDFYRDHPVLKAESEVRMHRLAIVDATRVVLRNGLELLGIEPLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COF2_BOVIN
Sequence: MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDIGDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  It is the major component of intranuclear and cytoplasmic actin rods (By similarity).
What are the official names of this protein?
Cofilin-2, Cofilin, muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton.
Protein: VQ3L_SHEVK
Sequence: MNYTLSTVSSATMYNSSSNITTIATTIISTILSTISTNQNNVTTPSTYENTTTISNYTTAYNTTYYSDDYDDYEVSIVDIPHCDDGVDTTSFGLITLYSTIFFLGLFGNIIVLTVLRKYKIKTIQDMFLLNLTLSDLIFVLVFPFNLYDSIAKQWSLGDCLCKFKAMFYFVGFYNSMSFITLMSIDRYLAVVHPVKSMPIRTKRYGIVLSMVVWIVSTIESFPIMLFYETKKVYGITYCHVFYNDNAKIWKLFINFEINIFGMIIPLTILLYCYYKILNTLKTSQTKNKKAIKMVFLIVICSVLFLLPFSVTVFVSSLYLLNVFSGCMALRFVNLAVHVAEIVSLCHCFINPLIYAFCSREFTKKLLRLRTTSSAGSISIG
What is the function of this protein?
Putative chemokine receptor.
What are the official names of this protein?
G-protein coupled receptor homolog Q2/3L.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: RS2_AERHH
Sequence: MAKVSMRDMLQAGVHFGHQTRYWNPKMKSYIFGARSKVHIINLEKTVPMFDDAMNFISSVAAKKGKVLFVGTKRAASEAVKEAAERCDQFYVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTREMEKLEKSLGGIKNMGGLPDVLFVVDADHEHIAIKEANNLGIPVVSIVDTNSNPDGVDYVIPGNDDAIRAVQLYLNAAADTVLEARAQDIVVQAEQDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FADA_VIBVU
Sequence: MKNVVIVDCLRTPMGRSKGGAFRHTRAEDLSAHLMKGILARNPQVNPSEIEDIYWGCVQQTLEQGFNVARNAALLAGLPIEIGAVTVNRLCGSSMQALHDGARAIMTGDAEICLIGGVEHMGHVPMNHGVDFHPGMSKHVAKAAGMMGLTAEMLGKLHGISREQQDEFAARSHARAHAATMEGRFKNEILPTEGHAADGTLFTLDHDEVIRPETTVEGLSQLRPVFDPANGTVTAGTSSALSDGASAMLIMSEEKANELGVTIRARIKGMAIAGCDPSIMGYGPVPATQKALKRAGLSIEDMDVIELNEAFAAQSLPCAKDLGLLDVMDEKVNLNGGAIALGHPLGCSGARISTTLINLMEAKDAKYGLATMCIGLGQGIATVFERP
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOA_BACSU
Sequence: MKLISWNVNGLRAVMRKMDFLSYLKEEDADIICLQETKIQDGQVDLQPEDYHVYWNYAVKKGYSGTAVFSKQEPLQVIYGIGVEEHDQEGRVITLEFENVFVMTVYTPNSRRGLERIDYRMQWEEALLSYILELDQKKPVILCGDLNVAHQEIDLKNPKANRNNAGFSDQEREAFTRFLEAGFVDSFRHVYPDLEGAYSWWSYRAGARDRNIGWRIDYFVVSESLKEQIEDASISADVMGSDHCPVELIINI
What are the official names of this protein?
Exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAXO1_RAT
Sequence: MNRKCICDLCSCGKHHCPHLPTKIYEKTEKPCFFSEYTEKYPTYLSYVPRESFKPKLEYQKVNIPMEGLSTTKRDFGTFNIVPVKHHLPEKATPIQDEMDFLTTYNQHYNYCPANRVNPIKPRDNKHQCNDKMECVPTYKADYLPWNQQKRSSIRPPQSYRPASCRFDHRTTHQDDYPIKNPVDTVSYKPPHGPKLCNIPLESMTSYKSSYVAHPMEKRCVYEGEKYKPSEVPFDSLTTHKDSYRGLIGEPAKTWKPAPNHPGLDIPFPSNTEFREKFQPWPTPKIVPKESIAYIPPEGKMDLLTTVQADYKCPNGVPAQSCRPVIHLKKSDRFESSTTNREDFKHWANIRREPVKPNHQLKFSDEPMEYMTTNRAHYVPHAPANTKSCKPTWSGPRVNIPLEGQTTYSTSFTPKEIQRCPASYPEPPGYIFDEVDAVGHRLYRPASGATSQESNHLGFGDA
What is the function of this protein?
May play a role in the regulation of cilium length.  Stabilizes microtubules at low temperature.
What are the official names of this protein?
Stabilizer of axonemal microtubules 1.
What is the protein family that this protein belongs to?
Belongs to the FAM154 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In multi-ciliated cells, localizes to the basal bodies and in non-ciliated cells, to the centrosome. In spermatozoa, colocalizes with microtubules along the length of the axoneme from its proximal end to its distal tip and with tubulin at the distal end of the flagellum and at the proximal centriole.
Protein: BAMA_SYNAS
Sequence: MSLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQYNSYTTEMVKGVIAGFENSSTDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGSYMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDITVSSDLAIFGQAGPRHGSAPVGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYTDTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCLMKSIDGIRQKKKFWWDQIKNDHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQLIAEGALVDEAFMEQVLGKPLAK
What is the function of this protein?
Involved in the central benzoyl-CoA catabolism.  Catalyzes the addition of one molecule of water to the double bond and the hydrolytic cleavage of C-C bond in the alicyclic ring, 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA) to yield 3-hydroxypimelyl-CoA.
What are the official names of this protein?
6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, 6-OCH-CoA hydrolase, 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: PURT_DESVV
Sequence: MASIGTPLTPTATRILLLGSGELGREVALEAMRLGVEVVAVDRYPNAPAMQVAHRSHVVSMLDGAALRAIIEAEKPYCIVPEIEAIATGTLLELEQEGYRVVPTARAARLTMDREGIRRLAAEELGLPTSPYRFASTEEEYRAAIETVGLPCVVKPVMSSSGKGQSLVRTPADIDSAWAYAQTGGRAGAGRVIVEGFVDFDYEITLLTVRHAGGVTFCDPIGHLQKDGDYRESWQPQPMDAVALEKARAMADAVTGALGGWGIFGVELFVRGDEVWFSEVSPRPHDTGLVTLISQNMSEFALHVRAILGLPVPLLRQNGPAASCVILAEGDSEAPRFHGVDAALAEQDTALCLFGKPEVHGRRRMGVALALGDDIDAARAKARRAAGSVTVEL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL35_DESHY
Sequence: MPKMKTHRGAAKRFKKTGTGKIVRHHAFTSHILEKKSPKRKRNLRKGTVMHKTDAKRIARLVAYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ENO_PARL1
Sequence: MAAIIDIIGREILDSRGNPTVEVDVLLEDGSLGRAAVPSGASTGAHEAVELRDGGSRYKGKGVLNAIAAVNGDIFDAIGGMDASEQIQIDRTMIALDGTSNKSNLGANAILGVSLAIAKAQAASLGQPLFRYIGGPAARVLPVPMMNIVNGGEHADNPIDIQEFMIMPVAAGSLADAVRMGSEVFHTLKAELKSAGHNTNVGDEGGFAPNLASTEEAIGFIMKAIEKAGYKPGDDIYLALDAASTEFFKNGVYNLQGEGKKLDAGGMVDYWADLVGKYPIISIEDGMAEDDWEGWKALTDRIGSKVQLVGDDLFVTNKRRLADGIAKGTANSILVKVNQIGSLTETLESVEMAHKASYTAVMSHRSGETEDATIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEALGPSGEYAGKSVLKG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RM55_DROME
Sequence: MLLKQLPQAVQQIRCISSATTAVTRLHRSVYCRLYPTVVVQPDGSTINIRYHEPRKIIKLPLDLSTLTDAERRARLEARKPRKKVKIMEEVEDNFNAKKYMKYIKKK
What is the function of this protein?
Involved in mitochondrial biogenesis and G2/M phase cell cycle progression.
What are the official names of this protein?
39S ribosomal protein L55, mitochondrial, L55mt, MRP-L55.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL55 family.
Protein: CYB_SORDA
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILALTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: S23IP_HUMAN
Sequence: MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKKAASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH
What is the function of this protein?
Plays a role in the organization of endoplasmic reticulum exit sites.  Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
What are the official names of this protein?
SEC23-interacting protein, p125.
What is the protein family that this protein belongs to?
Belongs to the PA-PLA1 family.
Protein: ZNUC_RICFE
Sequence: MEKPIIEFRNVSKKFGNKLPINNVSFTVKKNNITTLIGPNGAGKTTIVRLMLGLEKPTNGEIIIDPKLKIGYVPQKFGLTPDLPITVKKFLDLLAPSNFNSNIKEINSFIDLEHIKDQEISKLSGGQFQKVVLACSIVNKPDLIILDEPLQSLDVTSQQEFYQLINLIRKKLNITVFMISHDLFTVIKNSDQVICLNGHICCSGVPNEITPNSEFSNALSSLGFYTHHHDHRH
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYT_HELPJ
Sequence: MSAELIAVYKDEQIIDLESAKVLGLSDGIKALKGTEPIYFDDSPLALEVIRHSCAHLLAQSLKALYPDAKFFVGPVVEEGFYYDFKTTSKISEEDLPKIEAKMKEFAKSKLAITKETLTREQALERFKGDELKHAVMSKISGDIFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGDENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLPKGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFCSFEQIQSEVSAILDFTHKIMQAFGFSYEMELSTRPAKSIGDDKVWEKATNALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAEQPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKCDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQAQYKMPLKEFLNMVESKMQEVSF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSC10_CRYNB
Sequence: MPTPLALLLSAILIIGTYFAMPFWPFRKSNYDPRGKHCYITGGSSGLGKALAERLVKQGAHVTIVGRDSKKAEGVVEELKAIAAPGQIIQCIAADLTSPIASTNAIHAACKPHADQAPDYVYLCAGFSRPKLFVETTKQELKDGLDGVYWVSAYTAHEACQMMSKQRRTGKIIFVASFLSYVSFAGYSSYSPAKYALRGLSDALRSEMLLHNIDIHIFLPCGISGPGFDAENRTKPAVTKKIEEGDTPITPEVCAAALESGLKKGYYQITDNLVTEPIRLRSNGGVPTNNFLLDTLWLIVSSVGVPIWRMTADSAVRSFRAKVEKELEAKGYYVS
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase TSC10, 3-dehydrosphinganine reductase, KDS reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SCA4_RICRH
Sequence: DTSEFDPLANKEYTEEQKQKLEQEQKELLSQTTTPELEADDGFIVTSASSAQSTPSISALSGNISPDSQTSDPITKAVRETIIQPQKDNLIEQILKDLAALTDRDLAEQKRKEIEEEKEKDKTLSTFFGNPANREFIDKALENPELKKKLESIEIAGYKNVHNTFSTASGYPGGFKPVQWENQVSASDLRATVVKNDAGDELCTLNETTVKTKPFTVAKQDGTQVQISSYREIDFPIKLDKADGSMHLSMVALKADGTKPSKDKAIYFTAHYEEGPNGKPQLKEISSPKPLKFAGTGDDAIAYIEHGGEIYTLAVTRGKYKEMMKEVELNQGQSVDLSQAEDIIIGQGQSKEQPLITPQQTASSSVESPQYKQQVPPITPTNQPLQPETSQMPQSQQVNPNLLNAATALSGSMQDLLNYVNAGLTKEIDSNKQIDLIKEAATAILHNAKSDIAEKQTNIIALAENTVNNQNLTPDAKVAGVNAVLETIKNDQNTPDLEKSKMLEATVAITLNSENLEPKQKEQMLEKTVDVGLSLKDDASRAAAIDGITDAVIKSNLSTEDKGTMLIAVGDKVNVSELSNAEKQKLLGSVLKKGVEAQVLSPAQQQLMQQNLDKITAEQTKKDTIKKVNDILFDPLSSTELKTTNIQAITSNVLDGPATAEVKGEIIQEITNTVAGSSLEAQDKAEIVKGVGETIATHSDTSLSLPNKALIMASAEKGIVESKTNLPDRELMTKGLVDGIYEGKGGPEITKAVSSGIDNSNINDSEKEALKKAKDAASEATLDIETQNLTEGLKGQNIEEHKPRDDIYNKAQEVINAVNPVIEALEKPKAPVVSAEERIVQETSSILNNISKLAVEKVNNFRAMLSSNGNFKTLEKKKEESIKKVDELVKAFGTKSSTEEQQSFIKANLIDDKTLSKEVRLQTIDKLLQEQTQKQAEAIENPSVKTEDVRVVSGKSELKPISKDTPDIEKAKMVVGRDRVNIKENIKIMGALMNARDSIQSENVNKSTPIKRE
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1773_YERE8
Sequence: MSVTDIVLIVFIALLLAYAIYDEFIMNMMKGKTRLQIQLKRKSKIDCAIFVGLIAILVYNNVMANGEPLTTYLLVGLALIAFYLSYIRWPKLLFKNTGFFYANAFIEYRRIKSMNLSEDGILVIDLEQRRLLIQVRQLDDLEKIYNFFVENQS
What are the official names of this protein?
UPF0266 membrane protein YE1773.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYA_BURP6
Sequence: MKAAEIREKFLKFFESKGHTIVRSSSLVPGNDPTLLFTNSGMVQFKDVFLGAETRPYSRATTAQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWELLTSVYKLPADKLWVTVYHDDDEAYDIWAKEVGVPAERIIRIGDNKGARYASDNFWQMGDTGPCGPCSEIFYDHGPDVWGGPPGSPEEDGDRYIEIWNLVFMQFNRDAQGNMTRLPKPCVDTGMGLERIAAVLQHVHSNYEIDLFQQLIKASARETGVADLANNSLKVIADHIRACSFLIVDGVIPGNEGRGYVLRRIVRRAIRHGYKLGRKAPFFHKLVADLVAEMGAAYPELKEAEPRVTDVLRQEEERFFETIEHGMSILEAALAELDAAGGKTLDGELAFKLHDTYGFPLDLTADVCRERGVTVDEPAFDDAMARQREQARAAGKFKATQGLEYTGAKTTFHGYEEIAFDDAKVVALYVEGASVGEVKAGESAVVVLDHTPFYAESGGQVGDQGVLANAATRFAVGDTLKVQADVIGHHGELEQGTLKVGDVVRAEIDAARRARTARNHSATHLMHKALRDVLGSHVQQKGSLVDADKTRFDFAHNAPLTDDEIRRVEAIVNEQVLANAPGIVRVMPYDDAVKGGAMALFGEKYGDEVRVLDLGFSRELCGGTHVHRTGDIGLFKIVAEGGVAAGIRRVEAITGDNAVRYVQALDARVNAAAAALKAQPSELLQRIGQVQDQVKSLEKELGALKSRLASSQGDELAQQAVEVGGVHVLAATLDGADAKTLRETVDKLKDKLKSAAIVLAAVDGGKVSLIAGVTADASKKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTEPAKLPAALAGVKGWVEARL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APTX_MACFA
Sequence: MSNVNLSVSDVWRLMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQLKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKNPGLETHRKRKRSGDSDSIERDAAHEAEPGTGLEPGSNHNQCSVPPKKGKDAPIKKESLGHWSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTAISSLKAVTREHLELLKHMHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ
What is the function of this protein?
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair.  Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species.  Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined.  Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity).  Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
What are the official names of this protein?
Aprataxin, Forkhead-associated domain histidine triad-like protein, FHA-HIT.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage. Colocalizes with MDC1 at sites of DNA double-strand breaks. Interaction with NCL is required for nucleolar localization (By similarity).
Protein: HRCA_MYCBP
Sequence: MGSADERRFEVLRAIVADFVATQEPIGSKSLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDQLEDVKPLSSAERRAIQSFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHQLAQLREILGQALEGKKLSAASVAVADLASQLGGAGGLGDAVGRAATVLLESLVEHTEERLLLGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGHETASEQMVGTSMVSTAYGTAHTVYGGMGVVGPTRMDYPGTIASVAAVALYIGDVLGAR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ARAA_VIBPA
Sequence: MKIFNDKQVWFVTGSQHLYGPQVLESVAQNSEEIIAGLNSSDDISVSIANKGTVKTPDEILAVCRAANNDPDCIGLMLWMHTFSPAKMWIAGLTQLNKPFLHLHTQFNAALPWDEIDMDFMNLNQSAHGCREFGFIGTRLNIERKVVVGHWQEPQVHRDIDDWCRAAIGVNAGQHLKVARFGDNMRQVAVTEGNKVSAQIQFGYEVNAYGLGELSDVVNSISDADVNHQLDKYACMYEMSPDLFNDSDLKKLMAQEARLELGMESFLKSVGAGAFTNTFENLTGLTNLPGLATQRLMAKGFGYGGEGDWKTAAMTHIMKVMGQGKPGGTSFMEDYTYNFGEKGQVLGAHMLEVCPTIAAAKPRLEVHRHTIGCRCDIPRLIFSGQSGEALNVSIIDLGDRFRMIVNVIDTVTPPQSLPHLPVAHALWEPQPNLNIAAAAWIHAGGAHHAVYSQAVTLPMLADYAEILGIEMVVIDNSTNLRQFKQELRNNGVYYRLG
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: EFP_TROWT
Sequence: MASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASVVLENVDRRDCTYLYRDADSFVFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAPLYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQIQVPLFITVGTRIRVDTRTGAYIGKA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CROS8
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGNNVGCGRDHTLFAKADGKVKFEVKGPNNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.