PharMolix/UniProtQA huggingface dataset:
Protein: SYP_PYRIL
Sequence: MELLREAKPYTKDKLKTNLIEWFHWLLREAELYDVRYPVKGAYVWRPYGMKLRRNVENLIRRIHDETGHEEVLFPVFIPYEFFSKESQHIRGFEKEVFWVSKGGEGGERLILRPTSETAIMPMVKLWIQDYKDLPLRLYQIVSVFRAETKMTHPMIRLREISMFKEAHTVHATREDAERQIREAVEIYKRIFDEMCLAYMINKRPNWDKFAGAEYTIAFDTILPDGRTLQIGTVHYLGVNFTKVFEVTYLDIDGTRKLAHTTSYGISERSIAAMLITHGDDGGTTLPPKLAPIQVVIVPIFYGEEEMPTVMKFVDEVYRMLRDVGIRIHIDDRRDKTPGWKFYYWELKGVPLRIEVGRRDIEKRQVVVTRRDTLEKYAVSLGELVDAVKQLMSVVEDNLRKRAWEDLRNRLVKVEKVEDAKNAIREGKVVEVPWSGDDECGVKLQELVGADALGIPMDTDPSIGGFDMRDLACKEKRAEFWLRLSERY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFX_DESB2
Sequence: MPERLQVYKCEVCGNIVEVLNGGIGELVCCNQDMKLMSENTVDAAKEKHVPVIEKIDGGYKVKVGAVAHPMEEKHYIQWIELLADDKCYTQFLKPGQAPEAVFLIEAAKVVAREYCNIHGHWKAEN
What is the function of this protein?
Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center.  Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
What are the official names of this protein?
Desulfoferrodoxin, Dfx, Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: SECE_METKA
Sequence: MSTYEELISLLRDCKRVLRAARKPTWDEYIESAKIAGLGILIVGGVGFLIRVIVQLIELYT
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MCTR_RHIL3
Sequence: MTERPKIRVLLIDNHPLVLDGLKAVLETFDHIEVAGTAGLAQTGLEIGRQILPQVVLMDINMPKLSGIDAIELFRNELPQARVVMLSMHDSREYISSSVMHGAAGYILKDVSTDEIVSAIETVAGGGTYFSSGVFDALMGERVEEGSDPLTPRERDILGLIVAGRSNKEIAETLGITSATAETHRKNLKKKLGITTTAGLIRYALDHGIVSKVG
What is the function of this protein?
Member of the two-component regulatory system MctS/MctR, which activates mctP expression.
What are the official names of this protein?
Transcriptional regulatory protein MctR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP2_ROTS1
Sequence: MAELACFCYPHLENDSYRFIPFNSLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTSDNSRGMNYETSMFNKVAALICEALNSIKVTQSDVASVLSKIVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNAAFTMWKLTYLEHKLMPILDQNFIEYKITLNEDKPISESHVKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATFKSNNKNGNMIEFNLLDQRIIWQNWYAFTSSMKQGNTLEICKKLLFQKMKRESNPFKGLSTDRKMDEVSQIGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: ENO_CYTH3
Sequence: MSLIEEIVARQIFDSRGNPTIEVDVITENGLIGRAAVPSGASTGKHEAVELRDNDKSIYMGKSVLKAVANVNDIIAPELIGSHVFEQNLIDRLMIDLDGTANKGKLGANAILGVSLALAKAAAQEAGLPLYRYVGGVSANTLPVPMMNIINGGSHADNSIDFQEFMIMPTGAKSFTEAMRMGSEIFHNLAKVLKSKGMSTNVGDEGGFAPNIASNEDALITVIQAIEAAGYRPGEDVMIAFDAASSEFYDSETKLYHFKKSTGDKLTSSQMASYWADLVKRYPIVSIEDGMDEDDWSGWAELTKLVGDKVQLVGDDLFVTNVSRLQQGIDQGIANSILVKVNQIGSLTETISAVNLAKRNSYTSVMSHRSGETEDNTIADLAVALNCGQIKTGSCSRSDRMAKYNQLLRIEEELGEAAYFPGKNMRK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: F16PA_KLEP7
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALRARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGNTYSINEGNYIKFPQGVKKYIKYCQEEDKATQRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPEGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNNHMVEDVENFIKAFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIPB_MYCTU
Sequence: MRHTRFHPIKLAWITAVVAGLMVGVATPADAEPGQWDPTLPALVSAGAPGDPLAVANASLQATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTGASRIPRANARQAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYAFAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNGQMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
What is the function of this protein?
Peptidoglycan endopeptidase that cleaves the bond between D-glutamate and meso-diaminopimelate.  Binds high-molecular weight peptidoglycan, but does not degrade it.  Required for normal separation of daughter cells after cell division and cell wall integrity.  Required for host cell invasion.
What are the official names of this protein?
Peptidoglycan endopeptidase RipB, Macrophage invasion and intracellular persistence protein B, Resuscitation-promoting factor interaction partner B, Rpf-interacting protein B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: RS15_STRPJ
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIKQHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RLME_VIBC1
Sequence: MSKQKHSASSGRWLKEHFDDKYANEARKKGYRSRAYFKIEEIQTKDKLLKSGMTVVDLGAAPGGWSQYAAKIIGEEGQIIACDLLPMDPIAGVSFLQGDFRDEAVLDALLERIQPSMVDVVMSDMAPNIAGNNSVDQPRAMYLVELALDMCRQVLAPNGSFVVKVFQGEGFDQFVKEVRDMFKVVKIRKPDSSRARSREVFVVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET14_HUMAN
Sequence: MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAPNAKRKYLDEGETDEDKMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYCQHFVDTGHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETGITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFRGERGGFRGGRGGAHRGGFPPR
What is the function of this protein?
The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis (PubMed:24316715, PubMed:24407421, PubMed:25719671, PubMed:29348140, PubMed:27373337, PubMed:27281194).  In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core (PubMed:27627798, PubMed:27373337, PubMed:27281194, PubMed:29348140).  N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing (PubMed:24316715, PubMed:24407421, PubMed:25719671).  M6A acts as a key regulator of mRNA stability by promoting mRNA destabilization and degradation (By similarity).  In embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).  M6A regulates spermatogonial differentiation and meiosis and is essential for male fertility and spermatogenesis (By similarity).  M6A also regulates cortical neurogenesis: m6A methylation of transcripts related to transcription factors, neural stem cells, the cell cycle and neuronal differentiation during brain development promotes their destabilization and decay, promoting differentiation of radial glial cells (By similarity).
What are the official names of this protein?
N6-adenosine-methyltransferase non-catalytic subunit, Methyltransferase-like protein 14, hMETTL14.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
Protein: RL31_DECAR
Sequence: MKADIHPNYKEIQVNCSCGNTFTTKSTMSKDAFHVEVCSACHPFYTGKQKIVDTAGRVEKFNQKFGAMRGKSAA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: UREI_HELPY
Sequence: MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIICNIVVITYSALHPTAPVEGAEDIAQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTIPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWV
What is the function of this protein?
Functions as a specific, H(+)-activated urea channel that increases the rate of urea entry into the cytoplasm, resulting in activation of cytoplasmic urease at acidic medium pH.  Is essential for H. pylori gastric survival and colonization.  Is necessary for the adaptation of urease activity to the extracellular pH, as in the presence of urea, UreI rapidly enhances the production of ammonia in the extracellular medium when the pH of the medium was decreased to pH5 or below.
What are the official names of this protein?
Acid-activated urea channel, Urease accessory protein UreI.
What is the protein family that this protein belongs to?
Belongs to the AmiS/UreI family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_DEIGD
Sequence: MSLIVMATGGTGGHIYPAVAVSRELLARGHEAVLLGQRGGMEERVAAEQGLPFQGVNAGKLARSGQGRPDPRELLRAARGVAEARAFLRDARPGAVVGFGGFASLPGVLAAQTLGIPTVLHEQNARLGLTQRLAAGRARAVGTAYPHVLGLPEGKATLVGMPVREERLPRAEALAQLGLQDGPLTLLVMGGSQGSLALNHAVPDILREIFGPEGRAPEGPVQVLHATGPRWLAEVAPRVADLPWYKPVGYTNAVAAWSAADLAITRAGTGTLAEAAFHGVPLVMVPLPESAENHQYHNAVSVQEAGAGRVVEQEQLRGALGAAVLECAAAGTRAAMRKAAFLRSPVGAASRFADLVERHLR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL13_MYCTU
Sequence: MPTYAPKAGDTTRSWYVIDATDVVLGRLAVAAANLLRGKHKPTFAPNVDGGDFVIVINADKVAISGDKLQHKMVYRHSGYPGGLHKRTIGELMQRHPDRVVEKAILGMLPKNRLSRQIQRKLRVYAGPEHPHSAQQPVPYELKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GRPE_VIBVU
Sequence: MSNEENKINEEALKQQDAAEVEVEAVGTDADIEWNEEADESAAKIAELEAALLASEARVKEQQDSVLRAKAEVENMRRRTEQEIDKARKYALNRFAEELLPVIDNLERAIQAADAESEAVKPLLEGVELTHKTFVDVVSKFGLKEINPEGQPFNPEWHQAMSIQESPDHESNTVMFVMQKAMN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPA_STAAU
Sequence: MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
What is the function of this protein?
Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses.  Required for intramacrophage survival.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpA, Phosphotyrosine phosphatase A, PTPase A.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted intracellularly upon bacterial infection of macrophages.
Protein: SYP_BACC7
Sequence: MKQSMVFSPTLREVPADAEIKSHQLLLRAGFMRQNASGIYSFLPFGLKVLHKVERIVREEMERAGAVELLMPAMQAAELWQESGRWYSYGSELMRMKDRNAREFALGATHEEVITDLVRDEVKSYKKLPLTLYQIQTKFRDEQRPRFGLLRGREFLMKDAYSFHATQESLDEVYDRLYKAYSNIFARCGLNFRAVIADSGAMGGKDTHEFMVLSDVGEDTIAYSDTSDYAANIEMAPVVATYTKSDEAEKALEKVATPDQKAIEEVSAFLNIEAEKCIKSMVFKVDEKLVVVLVRGDHEVNDVKVKNVYGASVVELASHEEVKELLNCEVGSLGPIGVTGDIEIIADHAVASIVNGCSGANEEGFHYVNVNPERDFKVSQYTDLRFIQEGDQSPDGNGTILFARGIEVGHVFKLGTRYSEAMNATFLDENGKTQPLIMGCYGIGVSRTVAAIAEQFNDENGLVWPKAVAPFHVHVIPVNMKSDAQREMGENIYNSLQEQGYEVLLDDRAERAGVKFADADLFGLPVRVTVGKKADEGIVEVKVRATGESEEVKVEELQTYIANILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_CLOP1
Sequence: MSEVLQRITDPKEIKDLDEKELEILAEDLREFLIESVSNTGGHFASNLGVIDLTVALFKNFDFSEDRIIWDVGHQSYAYKILTGRKDKFNTLRQYGGLCGFPKRTESEYDFFATGHSSTSLSSAAGMARAQRLLGKDNKVIAVIGDGALTGGMALEALNDIGYRKDNLIIILNDNQMSICKNVGGLATYLNKLRMGVGYNKLKSDIGSTLDTTSFGKRVKNSLSKLKDGIKKIVVPSMYFEDIGLKYFGIVDGHNIRELNEVLSIAKNIKGPVIIHTVTKKGKGYELAEKNPNKYHGVSPFDLGEGVISKFASRNYSSTFGEEMIKLAKNDDKVVAITAAMPDGTGLKEFREEFPDRFFDVGIAEQHAVTLAAGMAAEGLKPFFAVYSTFLQRAYDQVLHDVCIQKLPVTLCLDRAGLVGEDGETHQGIFDISFLSPMPNMTIVAPKCIDEMEVILKWASNFNAPLAIRYPRGGDIDVNLKPLSKIEYGKWEKVQEGDKIAIVATGKMVQHAMIAAQKIKEEKNIDILIINATFIKPIDKELLNSLSKDGFKIVTIEDNIKKGGFGEGVLEYLNEIGHKEKIVTLAFNDKFIEHGKPDILYKINGLDAEGIKNTLIELL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MFF_XENLA
Sequence: MAEINRMQYEIDYTEGISQRMRVPEMLKVAPGNLGANLKAQQDMPIPGVVMEVPERIVVAGQSEESPFSRPSDLDFISGTNIGTLALKTPPRVLTLSERPLDFLDLEGLTPATPQSEEIRSSGHLKRDKFSSENALRQNGQLVRHDSMSAMSTLDTTLDATADDLALADAASLRRQIIKLNRRLLLLEEENKERVKHEMTMYSIIIIFGLLNSWLWLRR
What is the function of this protein?
Plays a role in mitochondrial and peroxisomal fission.  Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity).
What are the official names of this protein?
Mitochondrial fission factor homolog A.
What is the protein family that this protein belongs to?
Belongs to the Tango11 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein: RS5_BACP2
Sequence: MSRIDQSKLELEERLVTVNRVAKVVKGGRRFRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGTTIPHEIIGRFGAGNVLLKPASEGTGVIAGGPVRAVLELAGLADILSKSLGSNTPINMIRATLQGLSELKRAEDVAKLRGKSVEDLLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RBBP5_DROME
Sequence: MNLELLESFGQNYPEEFDGSLDCISLAVTCAFNKYGTLLAVGCNDGRIVIWDFLTRGIAKIISAHVHPVCSLSWTRNGHKLLSASTDNNVCIWDVLTGELEHKYRFPSPVLKVQFDPRNDNRLLVCPMRYAAVLVEVGGTHRCLPLDSDGDLNIVASFDRRGKHIYTGNAKGKILVLDVETFEVVASFRIIVGTSSATAVKSIEFARRGDAFLINTSDRVIRVYDSKEIITLGKDGEPEPIQKLQDLVNKTTWKKCCFSGDGEYICAGSARQHALYIWEKSIGNLVKILHGTKGELLLDVVWHPVRPIIASISSGLVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIADEDKSVDLNADAQQDEEIEVDVQKVEPVAAFCSSDEEGEDENALQFLPMAPEVEDPEDGWTGQDGLEPSAVMLGHMEPHDYEDDIMASKRRRMQLYDVSLPDAPTDETHPLISSKASKDKQQPVGGKKAAGRTKK
What is the function of this protein?
Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'.
What are the official names of this protein?
Retinoblastoma-binding protein 5 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCSB_STRLA
Sequence: MIDLIVSQGRVADRAAWMIEGAARTARALEERYGLKGHYVGEPAPHADDDWSVALPQARETLVAVREAATESIKGDNLTVLVNNTCSVSLATLPVVAREHPDAVVLYIDGHGDFNTPETTDTGYLGGMVLSGACGLWDSGHGAGLRPEQAVLVGSRDIDEGERELIRKAGVRVIPPGEATAQAVLDAVKDAPVWIHIDWDVLEPGSIPADYTVPDGMLPAQIRAVFEAIPAERLIGVELAELNAPADSERAEQAVAVILDMVAPAFDAAAARP
What is the function of this protein?
Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent.  Catalyzes the hydrolysis of N(omega)-hydroxy-L-arginine (NHA) to yield hydroxyurea (HU) and L-ornithine.
What are the official names of this protein?
N(omega)-hydroxy-L-arginine amidinohydrolase, hydroxyarginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: MIAB_SALPB
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENELGVGFYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_STAEQ
Sequence: MYEVKLDAFNGPLDLLLHLIQKYEIDIYDIPMKALTEQYMQYVHAMNQLEINVASEYLVMASELLMIKSKLLLPQTSIEEDIEEDPREDLVGRLIEYQNYKEYTEILNTMKEERDLYFTKHPTDLTHLETNESWDPNQTIDLTELIVAYQRVKNRVELNTPKSVEIKKETFTIQQATAQVTERLKQHESFNFFSLFTFHEPVEQVVTHFLAILEMSKSGIVNIKQTKQFDDIDIIRGVNYSIG
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: REG3A_HUMAN
Sequence: MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD
What is the function of this protein?
Has bacteriostatic activity.
What are the official names of this protein?
Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, HIP, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha.
What are the subcellular locations of this protein?
Secreted. Note=Found in the apical region of pancreatic acinar cells.