PharMolix/UniProtQA huggingface dataset:
Protein: DPO3A_HELPY
Sequence: MKENKAFTHLHLHTEYSLLDGANKIKILAKRVKELGMKSVSVTDHGNMFGAIDFYTSMKKEGIKPIIGMEAYIHNDDNLSSKETKQRFHLCLFAKNQEGYENLMFLSSMAYLEGFYYFPRINKKLLKEHSKGIIASSACLQGEVNYHLNTNNERNRKYGAKGYDEAKKIACEYQEIFEDDFYLEIMRHGILDQRFIDEQVIKMSLETGLKIIATNDTHYTMPNDAKAQEVAMCVAMGKTLNDKGRLKHSVHEFYIKSPEEMAKLFADIPEALENTQEIADKCVLEIDLKDDKKNPPTPPSFKFTKAYAQNEGLNFEDDASYFAYKAREGLKERLVLVPKEKHDQYKERLEKEIEVITNMKFPGYMLIVWDFIRYAKEMGIPVGPGRGSAAGSLVAFALKITDIDPLKYDLLFERFLNPERISMPDIDTDFCQRRRKEIIEYMIEKYGKYNVAQVITFNKMLAKGVIRDVARVLDMPYKEADDFAKLIPNRLGITLKGYEKNGEFIEGAWELEPKIKELVESNELAKQVWEYSLNLENLNRNAGVHAAALVVDSQKELWHKTPLFASEKTGGIVTQYSMKYLEPVDLIKFDFLGLKTLTVIDDALKIIKTQHKISVDFLSLDMDDPKVYKTIQSGDTVGIFQIESGMFQGLNKRLRPSSFEDIIAIIALGRPGPMESGMVDDFVNRKHGVEPIAYAFKELEPILKPTYGTIVYQEQVMQIVQTIGGFSLGEADLIRRAMGKKDAQIMADNKAKFVEGAKNLGHDGQKAANLWDLIVKFAGYGFNKSHSAAYAMITFQTAYLKTYYKHEFMAAMLTSESNKIESVARYIDEVRALEIEVMPPHINSSMQDFSVAEFKNQKGELEKKIVFGLGAIKGVGGEPIKNIIEERAKGDYKSLEDFISRVDFSKLTKKSLEPLVKSGSLDNLGYTRKTMLANLDLICDAGRAKDKANEMMQGGNSLFGAMEGGTKEQVVLDMIDLGEHDAKTLLECEYETLGIHVSGNPLDEFKEEIKGFKNLVKSIDIEELEIGSQAYLLGKIMEVKKKIGKRSGKPYGIADILDRYGKFELMLFEKQLNALEELDINKPLVFKCKIEEQEEVVRLRLFEILDLESAREVKIPKARYKDPEKQKEEVREIPPMEMLASSSCSLAIVLENDVKKEFLRQIKESALKHQGKRPLYLIIKDKDKQFKIQSDLMVNEKIKDDFKGLEWRDLA
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_SALPA
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQNGAMGIIVNKPLENLQIEGILEKLKITPESRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: Y9041_DICDI
Sequence: MDYDYDSSDLQYDDHKQNSNSKLDTSFRLFRTGTMSLFNNVVIVDFTYTPTSIYSCQYTIIDLNYKVLETQNILFSKSTNEPFNDKMDQINKMICDSIDKLSGRVLVLSPQSVNIPLLNLPMSVRIFDFQQIAKKKKIPLKSFDQFKDYYKNKKLNVDFKFTILSLFVDLTKNFIKSDFKFPSFKPILIDIKREGSLEGFFGHYIFTNIEIPIAIKNLINGYRDHLRENKLLLTQPELEIIDQQQEEHQQLQQQLQQQQQQLQQPQQKSEVQQKSIVENEENPPSEMESSISAPPPRRITPNELLDKKKRILFLKNLKKSLLLKKHQLNHISNPDAENDFSEIGETTPKKIKVLNLEKDNNNNNNNDKDNIYLEKDDSPTKENNSNIATTTNTNPNTNTNTNINTTTANNNEIANTDNNVNNVNQVTDQGDIKYHHQELIRQLTKLIRFEQKSLKTDSNNNNDNNDNIDDNNNNINKISPTPLSTSINDINNKNNTTNITSSIPPNSTNNNNNNNMNTIPLGTTNNDNIITIPLDTTNNNNNNNNNLNQINQNEFNHNILLQVQTILDKTILNQQYFLNEINNLSKRFDNMQIQFDSIYSKIKSNNNNNSIVNNGNNNNNGNNNNSIIDIQKKQKELLEKQNRILVLKNELQKLESQQEQVKLENDKDKIRDSKERYKFTGNKYPKKISNNNSSSSSSSSSSSNNIINNNNHQIDPYNTYQQKQKTSLQRRPPFNKPNTSNVFIKTKFRPINHSVSALPQKNTIMSSFRNFLKSFKK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0289041.
Protein: PT1_LACLA
Sequence: MTTMLKGIAASSGVAVAKAYLLVQPDLSFETKTIADTANEEARLDAALATSQSELQLIKDKAVTTLGEEAASVFDAHMMVLADPDMTAQIKAVINDKKVNAESALKEVTDMFIGIFEGMTDNAYMQERAADIKDVTKRVLAHLLGVKLPSPALIDEEVIIVAEDLTPSDTAQLDKKFVKAFVTNIGGRTSHSAIMARTLEIPAVLGTNNITELVSEGQLLAVSGLTGEVILDPSTEQQSEFHKAGEAYAAQKAEWAALKDAETVTADGRHYELAANIGTPKDVEGVNDNGAEAIGLYRTEFLYMDAQDFPTEDDQYEAYKAVLEGMNGKPVVVRTMDIGGDKTLPYFDLPKEMNPFLGWRALRISLSTAGDGMFRTQLRALLRASVHGQLRIMFPMVALVTEFRAAKKIYDEEKAKLIAEGVPVADGIEVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGEMAGDQTAVPLLMGMGLDEFSMSATSVLQTRSLMKRLDSKKMEELSSKALSECATMEEVIALVEEYTK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_BURVG
Sequence: MEQFHGTTIVSVRRGDKVALGGDGQVTLGNIVMKGGARKVRRIYNNQVLVGFAGGTADAFSLLDRFEAKLEKHQGNLTRAAVELAKDWRTDRMLRRLEAMLITADATTTLVITGNGDVLDPEGGICAIGSGGAYAQAAARALAENTDMSPREIVEKSLEIAGDMCIYTNHNRIIETIE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_STAAT
Sequence: MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAISAAAIKFAQQFEENSTFKIDVKRADKNFPMDTYELQRELGGAVLKHFDNISVNVKRPDHEIRVEVRLDAIYMYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLVHQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYB4_HORSE
Sequence: MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
What is the function of this protein?
Potent inhibitor of bone marrow derived stem cell differentiation (By similarity).  Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity).
What are the official names of this protein?
Thymosin beta-4, T beta-4.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LCPB_CORGL
Sequence: MDSPGQGEIARDSQGRPILDRYGRPVRVRPQPRQTPPTPRTPPVNETRVYQPRQTPPRQTPPRQTPPRQMPPRQTPPRQVPPQQQYQQPGQIGQVRPQPPVIAGDGGRRRKAISFKPRGCLGTIAGVLAVGLVLVFVVTLWADSKLNRVDATPATQVANTAGTNWLLVGSDSRQGLSDEDIERLGTGGDIGVGRTDTIMVLHMPRTGEPTLLSIPRDSYVNVPGWGMDKANAAFTVGGPELLTQTVEEATGLRIDHYAEIGMGGLANMVDAVGGVEMCPAEPMYDPLANLDIQAGCQEFDGAAALGYVRTRATALGDLDRVVRQREFFSALLSTATSPGTLLNPFRTFPMISNAVGTFTVGEGDHVWHLARLALAMRGGIVTETVPIASFADYDVGNVAIWDEAGAEALFSSMR
What are the official names of this protein?
Probable cell wall biosynthesis protein LcpB.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Localizes at regions of strong cell wall biosynthesis, such as the poles and the division plane.
Protein: MADD_RAT
Sequence: MVQKKFCPRLLDYLVIVGARHPSSDSVAQTPELLRRYPLEDHPEFPLPPDVVFFCQPEGCLSVRQRRMSLRDDTSFVFTLTDKDTGVTRYGICVNFYRSFQKRMPKEKAEGGAGPRGKEGAHAPCASEEAATESSESGSTLQPPSADSTPDVNQSPRGKRRAKAGNRSRNSTLTSLCVLSHYPFFSTFRECLYTLKRLVDCCSERLLGKKPGIPRGVQRDTMWRIFTGSLLVEEKSSALLHDLREIEAWIYRLLRSPVPVSGQKRVDIEVLPQEVQQALTFALPDPSRFTLVDFPLHLPLELLGVDACLQVLTCILLEHKVVLQSRDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVDLDSNRVIAPTNAEVLPILPEPESLELKKHLKQALASMSLNTQPILNLEKFHEGQETPLLLGRFSNDLQSTPSTEFNPLIYGNDVDSVDVATRVAMVRFFNSANVLQGFQMHTRTLRLFPRPVVAFQAGSFLASRPRQTPFAEKLARTQAVEYFGEWILNPSNYAFQRIHNNTFDPALIGDKPKWYAHQLQPIHYRVYDSNSQLAEALSVPPERDSESDPTDDSGSDSMDYDDSSSSYSSLGDFVSEMMKCDINGDTPNVDPLTHAALGDASEVEIDELQPQKEGEEPGPDSENSQENLPLRSSSSTTASSSPSTIVHGAHSEPADSTEVGDKAATGISKPLPPVPPSICKSTVDRRQTETGEGSVCQRTYDHPYFEPQYGSPAEEDDDEQGESYTPRFSQHASGSRAQKLLRPNSLKLASDSDAESDSRASSPNSTVSNNSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKTTPFPSLKGNRRALVDQKSSVIKHSPTVKREPPSPQGRSSNSSENQQFLKEVVHSVLDGQGVGWLNMKKVRRLLESEQLRVFVLSKLSRAVQSEDDARQDVIQDVEISRKVYKGMLDLLKCTVLSLEQSYAHAGLGGMASIFGLLEIAQTHYYSKEPDKRKRSPTENVNTPVGKDPGLAGRGDPKAMAQLRVPQLGPRAPSATGRGPKELDTRSLKEENFVASVGPEVIKPVFDLGETEEKKSQISADSGVSLASASQRTDQDSVIGVSPAVMIRSSSQDSEVSNSSGETLGADSDLSSNAGDGPGGEGSAHLASSRATLSDSEIETNSATSTIFGKAHSLKPKEKPASSPVRSSEDVSQRVYLYEGLLGRDKGSMWDQLEDAAMETFSISKERSTLWDQMQFWEDAFLDAVMLEREGMGMDQGPQEMIDRYLSLGEHDRKRLEDDEDRLLATLLHNLISYMLLMKVNKNDIRKKVRRLMGKSHVGLVYSQQINEVLDQLTNLNGRDLSIRSSGSRHMKKQTFVVHAGTDTNGDIFFMEVCDDCVVLRSNIGTVYERWWYEKLINMTYCPKTKVLCLWRRNGSETQLNKFYTKKCRELYYCVKDSMERAAARQQSIKPGPELGGEFPVQDMKTGEGGLLQVTLEGINLKFMHNQVFIELNHIKKCNTVRGVFVLEEFVPEIKEVVSHKYKTPMAHEICYSVLCLFSYVAAVRSSEEDLRTPPRPVSS
What is the function of this protein?
Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family (PubMed:9020086).  Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms (By similarity).  Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion (PubMed:9020086).  Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscular junction (By similarity).  Involved in up-regulating a post-docking step of synaptic exocytosis in central synapses (By similarity).  Probably by binding to the motor proteins KIF1B and KIF1A, mediates motor-dependent transport of GTP-RAB3A-positive vesicles to the presynaptic nerve terminals (By similarity).  Plays a role in TNFA-mediated activation of the MAPK pathway, including ERK1/2 (By similarity).  May link TNFRSF1A with MAP kinase activation (By similarity).  May be involved in the regulation of TNFA-induced apoptosis (By similarity).
What are the official names of this protein?
MAP kinase-activating death domain protein, Rab3 GDP/GTP exchange factor, RabGEF, Rab3 GDP/GTP exchange protein, RabGEP.
What is the protein family that this protein belongs to?
Belongs to the MADD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Cell projection, axon.
Protein: GCS2_ECOSE
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNEITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKMGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: HSLU_CROS8
Sequence: MSEMTPREIVSELDKHIIGQDAAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAIKMVRMQSIEKNRYRAEEMAEERILDVLIPPAKNNWGQPEQQQEPSAARQAFRKKLREGELDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKEQAIEAVEQHGIVFIDEIDKICKRGNVSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELQALTAEDFERILTEPNASVTVQYKALMETEGVHIEFTDDGIKRIAQAAWQVNETTENIGARRLHTVLERLMEDISYDASDLGGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSM_PSEAE
Sequence: MTVQYPTIADCVGNTPLVRLQRLPGETSNTLLVKLEGNNPAGSVKDRPALSMITRAELRGDIRPGDTLIEATSGNTGIALAMAAAIKGYKMILIMPDNSTAERKAAMTAYGAELILVSKEEGMEGARDLADKLQREGRGKVLDQFANGDNPEAHYHSTGPEIWQQTGGSITHFVSSMGTTGTIMGVSRYLKEQNPAVQIVGLQPMEGSAIPGIRRWPQEYLPKIYDASRVDRVVDMHQDEAEDIMRRLAREEGIFCGVSSGGAVAAMLRLSRELENAVLVAIICDRGDRYLSSGVYDPR
What are the official names of this protein?
Cysteine synthase B, CSase B, O-acetylserine (thiol)-lyase B, OAS-TL B, O-acetylserine sulfhydrylase B.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: NPRE_BACAM
Sequence: MGLGKKLSVAVAASFMSLTISLPGVQAAENPQLKENLTNFVPKHSLVQSELPSVSDKAIKQYLKQNGKVFKGNPSERLKLIDQTTDDLGYKHFRYVPVVNGVPVKDSQVIIHVDKSNNVYAINGELNNDVSAKTANSKKLSANQALDHAYKAIGKSPEAVSNGTVANKNKAELKAAATKDGKYRLAYDVTIRYIEPEPANWEVTVDAETGKILKKQNKVEHAATTGTGTTLKGKTVSLNISSESGKYVLRDLSKPTGTQIITYDLQNREYNLPGTLVSSTTNQFTTSSQRAAVDAHYNLGKVYDYFYQKFNRNSYDNKGGKIVSSVHYGSRYNNAAWIGDQMIYGDGDGSFFSPLSGSMDVTAHEMTHGVTQETANLNYENQPGALNESFSDVFGYFNDTEDWDIGEDITVSQPALRSLSNPTKYGQPDNFKNYKNLPNTDAGDYGGVHTNSGIPNKAAYNTITKIGVNKAEQIYYRALTVYLTPSSTFKDAKAALIQSARDLYGSQDAASVEAAWNAVGL
What is the function of this protein?
Extracellular zinc metalloprotease.
What are the official names of this protein?
Bacillolysin, Neutral protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31_WIGBR
Sequence: MKKKIHPMSLDILATCSCGNSLKIKSTIKKDILLDVCNKCHPFYTGTQKKLNIGGRVSKFKKRFDNIVYKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NQOR_ECOLI
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What is the function of this protein?
It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing.  It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide.  It prefers NADH over NADPH.
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: MAMB_MAGSA
Sequence: MKFENCRDCREEVVWWAFTADICMTLFKGVLGLMSGSVALVADSLHSGADVVASGVTQLSLKISNKPADERYPFGYGNIQYISSSIVGSLLLIGASFLMYGSVMKLISGTYEAPSIFAAVGASVTVIVNELMYRYQICVGNENNSPAIIANAWDNRSDAISSAAVMVGVIASVIGFPIADTIAAIGVSALVGRIGLELIGTSIHGLMDSSVDTELLQTAWQVAMDTPMVHSIYFLRGRHVGEDVQFDIRLRVDPNLRIKDSSMVAEAVRRRIQEEIPHARDIRLFVSPAPAAAARA
What is the function of this protein?
Plays a dual, essential role in magnetosome formation; required for magnetosome vesicle formation as well as biomineralization (PubMed:20212111) (Probable).  Probably binds and transports iron (By similarity).  Requires heterodimerization with MamM for stability (By similarity).
What are the official names of this protein?
Magnetosome protein MamB, Probable iron transporter MamB.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein.
Protein: PTH_ROSCS
Sequence: MWLIVGLGNPGETYARTRHNIGFRVVTELAQRHHLRFTHKRAKAEIAEGEIAGQRVALALPQTYMNLSGQAVVGLRQWYKIDPATELLVVYDDVDLPFGVLRLRERGSAGTHNGMRSIVALLGSQVFPRLRIGIDRPPVAWNLADYVLARFTPEQEAQLPEVTRRAADALELVLREGIVVAMNRINAPPPKPEKKRGSETSDPSAESADHAGGG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSCF_DICDI
Sequence: MIFNNLKNQNKIINFLIIFYFLSFLKQIESQSINITSSSSSWQCRGDLVYRNVSNRIEDEKIGFNFVQYNGTYQSCVIPCPSPFFTINEWNKFLNMSLVMGTISFFSGLFLLVTYSPIVNKTHNRHTIGVMCMSFGVCLAMCSDMWNFGSNFTEKSICPSPGQYLSTSNARCLSSGIFLQFGGVFGFLNWTLLSFDLFMNIKGIITKNYDKYYVSGTFIIAIIFTFVPIVNDQYSMSYIGLGCWLGSAMYQLIFFWILLSICLIVSSVFIILILKEVYIIIKLSKQKTSLKGNIRPLICISITGFAFFYMFFYYISIVVEGDYYERVLNEYTDCLMDPTKDISECKSPRMSVASEFVFLLCLRLLGIGAFIFYGINNKVKKIWLNSYWFNNSFVEKYISRKSADNDKSNSNGSKVLYRTNNTNNNGSFNTGLESSIIEMSTNSNKEESSLNSVDEI
What are the official names of this protein?
Frizzled/smoothened-like sans CRD protein F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLPP_CAMJE
Sequence: MFIPYVIEKSSRGERSYDIYSRLLKDRIIMLSGEIHDELAASIVAQLLFLEAEDPTKDIYLYINSPGGVITSGFSIYDTMNYIKPDVCTICIGQAASMGAFLLSCGAEGKRFALPNSRIMIHQPLGGARGQATDIEIQAKEILRLKTILNDILAKNTKQKVAKIAKDTERDFFMSAQEAKEYGLIDKVLEKSFK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_MYCTU
Sequence: MTEPDVAGAPASKPEPASTGAASAAQLSGYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVFAEDPRVNPEAELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLLTDGNIARAVRGEKIGTLVTT
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFAC_ECOLX
Sequence: MKHKKKNRLVVAISVALIPYIGVTGDIPDSFRDLWGEQDEFYEVKLYGQTLGIHRIKTTPTHIKFYSPESILDKINLKKEKEKELSVFFTNSFSRNGNMSCQGNTTIQYNCNYIKTKSVDVIVDDVDNVVNLFIGNEFLDSEAHNDEYHQLSRNVKKAFIQSQTINLSDSGKYKRLSISGNSALGITDTSYAVLNWWMNYNKSNGYSNNEKTINSLYFRHDLDKRYYYQFGRMDRTDLSQSISGSFNFNLLPLPDIDGIRTGTTQSYIKNTDKFIASPVTVMLTNFSRVEAFRNDQLLGVWYLDSGVNELDTARLPYGSYDLKLKIFENTQLVREEIIPFNKGRSSIGDMQWDIFVQGGNIVNDNDRYIEKQNNHKSSINTGLRLPITKNISVQQGVSVIDNKSYYEGSLKWNSGILSGSLNSEFSFLWGDNAKGNYQSISYTDGFSLSFYHNDKRVDNCGRNYNAGWSGCYESYSASLSIPLLGWTSTLGYSDTYSESVYKSHILSEYGFYNQNIYKGRTQRWQLTSSTSLKWMDYNFMPAIGIYNSEQRQLTDKGGYISVTITRASRENSLNTGYSYNYSRGNYSSNELFVDGYMTSTNNGDYHEAGMRFNKNRHNAEGRLSGRINNRFGDLNGSFSMNKNRNTNSTNHSLTGGYNSSFALTSDGFYWGGSTAGLTKLAGGIIKVKSNDTKKNLVKVTGTLYGDYSLGSNDNAFIPVPALTPASLIIEDNNYGDNNISILAPTNNDMFMLPGNVYPVEIETKVSVSYIGRGFDPNGTPLSGAHVLNEPHVILDEDGGFSFEYTGNEKTLFLLKGRTIYTCQLGKNKVHKGIVFVGDVICDINSTSSLPDEFVKNPRVQDLLAKNDKG
What is the function of this protein?
May serve as anchor for the fimbriae in the outer membrane.
What are the official names of this protein?
CFA/I fimbrial subunit C, Colonization factor antigen I subunit C.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane.
Protein: NIT1_SYNY3
Sequence: MKPYLAAALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFAFLGNETEKLEQATAIATATEKFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNVPDGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAAFTAYTGKDHWQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGEKPGLAIAEINPDRLKQVRQQMPSLQHRVFV
What is the function of this protein?
Hydrolyzes deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate (alpha-KG) and cysteinylglycine, alpha-ketoglutaramate (a-KGM), and no activity on glutathione or L-glutamine.  May function as a metabolite repair enzyme.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1, syNit1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: HMW1_MYCGE
Sequence: MAKNKQSVFEEKNYTQTEPENIFGDLYDGKSTVEEDPNIKVAYDADGNGYYIAFNKETGVYYDPYGDTEYDISQLFDENGNPFVFDEKQEENDYLKYVGNPDYGSYDENGEWVWSGYFENDQWISTKESQPTDENYGFDSDLPPEVKQPESVEDNYGFDNDLPPEVKQPESVEDNYGFDNDLPPEVKQPESVVDQPSSDDYFAKQPTDENYGFDNDLPPEVKQPESVVDQPSSDDHFAKQPESTTDSYSFDSDLPQPTLDQPSLDDHVQYNFDHHEELKPVAEEQNNYQVGFDQVQANLDNNEEIQPTAEKKVTTDFESKQAQVVDSYQLPIDTDQQDQTTFSSSFETQPTVEQFDQVNSEVNDQFKPEITKEPVLESSFNKQDVVETSDLNSESNLYSENNKDATNNDSLNSEFIQLNSNSETASDDVHYESKSEPIHDYKFGSDLSQSNSNNSLESEPVKFNSETAPDAHFESQSEPVDQVQYDIYQNEELKPTLDQPSSDDYFAKQPTDENYGFDNDLPPEVKQPESVVDQPSSDDHFAKQPESTTDSYSFDSDLPQPTLDQPSLDDHVQYNFDHHEELKPVAEEQNNYQVGFDQVQANLDNNEEIQPTAEKEVTTDFESKQAQVVDSYQLPIDTDQQDQTTFSSSFETQPTVEQFDQVNSEVNDQFKPEITKEPVLESSFNKQDVVETSNYTNNLQKFDIQSDNKITITTKKSSPQIPTTLPISFVSNRIEYKPVETLALDNKESQQEQITINSITEDSKTLAKTLSVQLQQINSLNNQSIVTSESVRLDKKDDQLTINTVNSEDQQPKIEVFVKAKEPVEEHSITQNKQSVEDKSELDNFNKKSDLYKIISELKRGELNPTINFDAIFQMNDYQMSVKQSFIHLNDFVTNYKNQISERYLIIKKELQSELSRLIDQNENLNVQFNNAKNLTTLQKEEMIRSLASDFAIAYKPSNSYEQLQKSGEIMRHVQRAITENEKKIESIQGSLKQLKTVYNSCCETIMNNINKLDNTLRFAKKEKDPLLLSNFDSVTDNGLVEPNQLMDDLIDFSNTFDNISNEQLDDFIYENMDRNIDFEFEGFNNDFVDIDAKVMDSMSAFSVNDLDIETLVPDRTSNFSSLLDEDLFESSGDFSLDY
What is the function of this protein?
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma.  This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle (By similarity).
What are the official names of this protein?
Cytadherence high molecular weight protein 1, Cytadherence accessory protein 1.
What are the subcellular locations of this protein?
Cell projection, attachment organelle membrane. Note=Localizes specifically to the attachment membrane.
Protein: RL22_SYNJA
Sequence: MADPSPEIKAVARYIRMSPYKVRRVLNQIRGRTYADALILLEFMPYAACEPVRKVLRSAVANAEHNNGLDPRDLVISKAYADQGPTLKRFRPRAQGRAYPIRKRTCHITIAVRPIEPEAATAS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RSMJ_ACIBT
Sequence: MEKNCGSGQSKLKALRMHIYFEVDFQEQAQHYQAVLYSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSANGMKMQPDWKAEIPRLKRATLKSEMIARACQLGEKPVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQHDPFLSQFMDRIQLIFADSASYLQQLDQEEKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGDHLLELAKKVAKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.