PharMolix/UniProtQA huggingface dataset:
Protein: VSP27_BOTPI
Sequence: VVGGDECNINEHRSLVAIFNSTGFFCSGILLNQEWVLTASHCDSTNFQMK
What is the function of this protein?
Snake venom serine protease that interferes with the hemostatic system of the prey.  It preferentially degrades the Bbeta chain (FGB) of fibrinogen, with minor effects on the Aalpha chain (FGA).  It presents a lower ability to degrade fibrin clots than BpirSP41.  It hydrolyzes chromogenic substrates S-2238 (used for testing thrombin activity), S-2222 (factor Xa), S-2266 (glandular kallikrein and factor XIa), S-2302 (plasma kallikrein, factor XIa and XIIa), and S-2251 (plasmin).  It shows a decrease in the clotting time of human plasma in the presence of increasing doses of the enzyme.  Its minimum coagulant dose (MCD) is 3. 5 ug.  It also promotes platelet aggregation in a concentration-dependent manner in the presence or absence of calcium.  It also shows 20% inhibition of the hemolytic activity promoted by the complement pathways and possess only a minor role in the induction of edema and pain in rat.
What are the official names of this protein?
Thrombin-like enzyme BpirSP27, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: REP_TYCS1
Sequence: MAQPKRFQINAKHYFLSFPKCSLSKEEALEQLLQLQTPTNKKYIKICRELHEDGQPHLHMLIQFEGKFNCKNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIDKDGDVLEWGTFQIDGRSARGGQQTANDAYAKAINAGSKSEALDVIKELAPRDYILHFHNINSNLDRVFQVPPAPYVSPFLSSSFDQVPDELEHWVSENVMDAAARPWRPVSIVIEGDSRTGKTMWARSLGPHNYLCGHLDLSQKVYSNNAWYNVIDDVDPHYLKHFKEFMGSQRDWQSNTKYGKPIQIKGGIPTIFLCNPGPQSSFKEYLDEEKNQTLKNWAIKNAIFVTIHQPLFTNTNQDPTPHRQEETSEA
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, Protein C1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RPOC_SULDN
Sequence: MSKLVPIEVTEDRRPTDIKQIQFRLASPEKVMSWSHGEVKKPETINYRTLKPERDGLFCAKIFGPVRDYECLCGKYKKMRYKGVVCEKCGVEVTSTKVRRIRMGHIELVTPVAHIWYVSSLPSRIGTLLGIKMKDLERVLYYEAYIVESGGEAYYDAEAKTPVLKYDVLNEEQYRTLVSRFGELGFKARMGGEVVRDLLDSIDLVDLFTQLKEDIELTKSEAKTKTIAKRLKVIESFLNSGNNPAWMMLTVLPVLPPDLRPLVSLDGGKFAVSDVNDLYRRVINRNQRLKRLVELEAPEIIVRNEKRMLQESVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRTVIVVGPSLSMDECGLPKKMALELFKPHLIAKLEDKGYATTVKAAKKMIEDKTNEVWECLAEIVDGYPVLLNRAPTLHKLSIQAFHPKLIDGKAIQLHPLVCAAFNADFDGDQMAVHIPLSSAAIAEAKVLMLASMNILLPASGKAIATPSQDMVLGIYYITLEKNGVKGSNKLFANVDEVRIAIEHDALDIHAKVRTRDDGRIIHTTAGRMLLKAILPNFVPSELWNRVMKKKAINEVVDYVQKHGGIGVTAGFLDRLKNLGFKHATEAGISISIDDIKIPAGKEAKIAESKNRVFEIQKQFEAGLLTEQERYNKIIDVWTDTNNTLATQMMDLVQTDKAGFNSIHMMADSGARGSAAQIRQLAGMRGLMAKPSGEIIETPIISNFKEGLNVVEYFISTHGARKGLADTALKTANAGYLTRKLVDVAQNVKIVEHDCHTHEGIEISDISDQNTLIESLEDRLNGRVLADDVIDPISNEILFAEGTLLDEVSAKVIAEAGIKTAYIRTPTTCKSENGICALCYGVNLATGQIVRRGEAVGIIAAQSIGEPGTQLTLRTFHVGGTASSTAQERQVVAEKEGFIRYYNLKTYVSKEGRNIVANRRNAAVLLVEPKIKAPFSGRVEIQTVHDEVIISVSSKTDTIRYVLRKNEIAKPNELAGVGGQIEGKYYFPYESGAEVQEYESIVETIKDGWNVPSRIPYASEVLVANGAPVTQKIFAKEDGVVKYFLLRGDYLERFEGLKAGYEVIEKGLFATVVDSNNREAVRHYIARGSIIVAEDDAVVDPKTLIAKPKNDESTVIAEWDPYSNPIISETSGTVKFEDIIIGTTATEQYDELTGKTRLMISDHVPAEYKPTIVLASEDGELLRYQVQSKTSIYVEDGAKVKVADIIAKTPKALQKSSDITGGLPRVSELFEGRRPKATALISEIDGVVSFGKSLRGKIRIIVASDNGILKEYFVDKSHTPVVNSGDFVHAGERLTSGIISSHELLRIMGVKTLYNYLVSEVQQVYRSQGVNISDKHIEVIFTQMLRQVKILKSGDTKFIEGDLISKVKFAQENEKIIKLGGRPAIAEPFLVGITRAAVSADSIISAASFQDTTKVLTEAAVSAKVDDLNDLKENVIIGRTIPVGTGIYKDQEIMFGYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PIMT_DESPS
Sequence: MIDNYSTAREKMLREQIVARGVTDMATLDAILEVPRHFFVDEGQRMRAYGDYPLSITEGQTISQPYIVAYMTSLLQLTASDTVLEIGTGSGYQAAILSKICRQVYTVECIHSLLNKARKVFDSLRYFNIRSKYDDGSRGWSEFAPYDAIIVTAGSPEIPTPLLDQLADGGRMVIPVGPRYEQVLKRVTKEGDDFVVEDLAPVRFVDLVGVHGWK
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM31_CONLE
Sequence: MLKMGVLLFIFLVLFPLTTLELDTDRPVERHAAIKQDLKPQERRGIRLHAPRDECCEPQWCDGACDCCS
What are the official names of this protein?
Conotoxin Lp3.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASSY_YERPS
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB083_HUMAN
Sequence: MEDYALTFGINPFIALMIQPIVTMTVVDNQGLGLPVDIQHKAKPSPKASQMLPPDLGPPSFQNLLSPSEKLEPWDPGMRKLTVQTCGLTFIHPAGHGLCHPTAEASAETLSSTALNRPSVREGACNEKSTENKKPQDSVLWSHSRWFQGN
What are the official names of this protein?
Folate transporter-like protein C2orf83.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
Protein: FAA28_MYCBO
Sequence: MIVRSLPAALRACARLQPHDPAFTFMDYEQDWDGVAITLTWSQLYRRTLNVARELSRCGSTGDRVVISAPQGLEYVVAFLGALQAGRIAVPLSVPQGGVTDERSDSVLSDSSPVAILTTSSAVDDVVQHVARRPGESPPSIIEVDLLDLDAPNGYTFKEDEYPSTAYLQYTSGSTRTPAGVVMSHQNVRVNFEQLMSGYFADTDGIPPPNSALVSWLPFYHDMGLVIGICAPILGGYPAVLTSPVSFLQRPARWMHLMASDFHAFSAAPNFAFELAARRTTDDDMAGRDLGNILTILSGSERVQAATIKRFADRFARFNLQERVIRPSYGLAEATVYVATSKPGQPPETVDFDTESLSAGHAKPCAGGGATSLISYMLPRSPIVRIVDSDTCIECPDGTVGEIWVHGDNVANGYWQKPDESERTFGGKIVTPSPGTPEGPWLRTGDSGFVTDGKMFIIGRIKDLLIVYGRNHSPDDIEATIQEITRGRCAAISVPGDRSTEKLVAIIELKKRGDSDQDAMARLGAIKREVTSALSSSHGLSVADLVLVAPGSIPITTSGKVRRGACVEQYRQDQFARLDA
What is the function of this protein?
Involved in the biosynthesis of phthiocerol dimycocerosate (PDIM), a cell wall-associated lipid found only in pathogenic mycobacteria.  Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase Mas for further chain extension.
What are the official names of this protein?
Long-chain-fatty-acid--AMP ligase FadD28, Acyl-AMP synthetase, Long-chain fatty acid adenylyltransferase FadD28.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TAT_HV1Z6
Sequence: MDPVDPNLEPWNHPGSQPKTACNRCHCKKCCYHCQVCFITKGLGISYGRKKRRQRRRPSQGGQTHQDPIPKQPSSQPRGNPTGPKE
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: RS6_LACAC
Sequence: MATTKYEVTYIIKPDIDEDNKKALVENYDKVIADNGGTMVESKDWGKRRFAYEIDKYREGTYHIMTFTADNADAVNEFSRLSKIDNAILRSMTVKLDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PCP_STAA8
Sequence: MHILVTGFAPFDNQNINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDNIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHTLYHLGYLQDKHYPHLRFGFIHVPYIPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLHLALGTTE
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADB_THEGJ
Sequence: MLSTGVKSLDELLGGGFGEGVLTQIYGPYATGKTTLAVQTGLLSGKKVAYVDTEGGFSPERLSQMASARGLDPEEALSRFLLFTPGDIREQRRVIGSLKRLITPEFSLVVVDSITAHYRAEEDWRSLTSELGKQLQVLLWIARKHRIPVLVINQVHFDARAERTRPVAEQTLGYRCKDILRLDKLPTPGKRVAILERHRFRPEGGMVYFKITEKGIEDVSD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange.
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: THII_STRZT
Sequence: MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVTADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKEGMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAYLSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIREVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTFDISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAEKDEVDDLIDNLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LEPIN
Sequence: MSNLTARVIPCLDIKDGRVVKGVNFVNLVDAGDPVESAAIYEENLADELCFLDITASSDRREILLHLVERIAEKIFIPFTVGGGIRTVDDVKAVLEKGADKVSINTAAFQNPKLLTYSSEIYGSQCIVCAIDVKHEKERDRYEVFLHGGRTATGREALDWAQEAAEKGAGEILLTSMDRDGTRNGFDIHLLKNFSSSLGIPIIASGGAGNPEHMVEAILRGKADAVLAASIFHFGEYSIRETKKAMEEMGISVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_ANADE
Sequence: MPARPTPPAVPLALALAAALAAPAPAAAARVKELADVVGVRENALYGYGLVVGLAGTGDSERVLFTQQSVAGMLGRLGIRIDPKDVRSRNVAAVMVTARLPPFARPGTRIDVAVASMGNARSLAGGLLLVTPLSGGDGKVYAVGQGPVQVAGYDAGAGGAELRKNTPTSGRVAGGATVERAVDFALGQAPLVLALRRPDLTTASRVAAAVNAKLGAGTARAVDPAAVELSPPPARKDDAVGFLAEVELLEVEADQRARVVVSERTGTVVAGDGVRLRPVAVAHGGLQVRVQRDPAVSQPAPFGAGRTVEATRDRAAAAEGAGGVVALPAAASVKDLARALDLLGATPRDLVAVLEAIRAAGALDADLEVLE
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: SYFA_ENT38
Sequence: MSHLAELVANATAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKSDLESAALNARLAEETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKEQAPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDKNISFTNLKGTLHDFLNNFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSLD5_ORYSJ
Sequence: MSVDYANYTVLMPPTPDNQPSGGAPPAAPSAGGARPGDLPLPPYGSSSSSRLVNRRGGGDDGAKMDRRLSTARVPAPSSNKSLLVRSQTGDFDHNRWLFETKGTYGIGNAYWPQDNVYGDDGGGGAVKMEDLVEKPWKPLSRKVPIPPGILSPYRLLVLVRFVALFLFLVWRVTNPNMDALWLWGISIVCEFWFAFSWLLDQMPKLNPINRAADLAALKEKFESPSPTNPTGRSDLPGLDVFISTADPYKEPTLVTANTLLSILATEYPVEKLFVYISDDGGALLTFESMAEACAFAKVWVPFCRKHSIEPRNPDSYFTQKGDPTKGKKRPDFVKDRRWIKREYDEFKIRVNSLPDLIRRRANALNARERKLARDKQAAGDADALASVKAATWMADGTHWPGTWLDPSPDHAKGDHASIVQVMIKNPHHDVVYGEAGDHPYLDMTDVDMRIPMFAYLSREKRAGYDHNKKAGAMNAMVRASAILSNGPFMLNFDCDHYIYNCQAIREAMCYMLDRGGDRICYIQFPQRFEGIDPSDRYANHNTVFFDGNMRALDGLQGPMYVGTGCLFRRYAIYGFNPPRAIEYRGTYGQTKVPIDPRQGSEAMPGAGGGRSGGGSVGGDHELQALSTAHPDHEAPQKFGKSKMFIESIAVAEYQGRPLQDHPSVLNGRPPGALLMPRPPLDAATVAESVSVISCWYEDNTEWGQRVGWIYGSVTEDVVTGYRMHNRGWRSVYCITRRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSKNNAVLASRRLKFLQRMAYLNVGIYPFTSLFLIMYCLLPALSLFSGQFIVATLDPTFLSYLLLITITLMLLCLLEVKWSGIGLEEWWRNEQFWVIGGTSAHLAAVLQGLLKVVAGIEISFTLTAKAAAEDDDDPFAELYLIKWTSLFIPPLAVIGINIIALVVGVSRTVYAEIPQYSKLLGGGFFSFWVLAHYYPFAKGLMGRRGRTPTIVYVWAGLISITVSLLWITISPPDDSVAQGGIDV
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein D5, OsCslD5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: FABZ_PSEPF
Sequence: MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVLIIEAMAQAAGILGFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQIWKFECQASVDGKPVCSAEIICAERKL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRP4
Sequence: MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVEHAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDLALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGGATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADGDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCKB_RAT
Sequence: MEEIVGLREGSPRKPVPLQELWRPCPRIRRNIQGSLEWLKERLFRVGEDWYFLVALGVLMALISYAMNFAIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVILEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPENKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNSEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYCQRTSLFFLKSNGFTSKLLATSKPLYSALAAVVLASITYPPGVGRFMASRLSMSEYLETLFDNNSWALMTKNSSPPWSAEPDPQNLWLEWCHPQMTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFVYGAAIGRLFGEVLSLAFPEGIVAGGKVSPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVSGQIVHALPVLMAVLAANAICQSYQPSFYDGTIIVKKLPYLPWIRGRKIGSHLVTVGHFMNCTLTTLAKDMPLEEVIKVVISTDVTQYPLVETTESQVLVGIVKRTHLVQSLHTDSASWAPGQQPCLQDILANGCPTQPVTLQLSTETSLHETHNLFELLNLQLLFVTSRGRAVGSVSWVELKKAISTLTNPPAPK
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.  May be important in urinary concentrating mechanisms.
What are the official names of this protein?
Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. CLCNKB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Recruited to the plasma membrane in the presence of BSND protein, whereas remains in the Golgi in its absence.
Protein: HLDD_BURP0
Sequence: MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQIAGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNLGTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRWLFGQL
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: NAL4E_MOUSE
Sequence: MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI
What is the function of this protein?
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 4E, NALP-epsilon.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
Protein: TBB5_PANTR
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Tubulin beta-5 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.