PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_BURM7
Sequence: MTKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAQTIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTRVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKTVGEHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAVKDIASNTLYVVQGHDHPWLRSRELVAGNVSWVAGEPPADGARCGAKTRYRQADAPCAFGRAAQAGDERFSLVFDEPQWAVTPGQSAVLYDGDVCLGGGIIESAATGRAGTAPAGRAPALVEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCS5_ECOLX
Sequence: MKILYSFLLLPFFSCAFSVDSMIKFSGEDDFFLVNGNSKEREYIYVTLSELISEKNNRRDEIFYNADNVPLWPISAEPADIIISSGEQVKIKINKNYTPVGGDRIFGINFSPDTLNDNDRNQYNIPFGYKAWLIVPGTESESGTVDVSKVSEKNKYIIKNNTNKVMDVWADYCGSYNNNKCRVQLITRPYSEKKIEIDSNNNPIEFTFSIYIGRERKLIKRKIL
What are the official names of this protein?
Uncharacterized 25.9 kDa protein in CS5 3'region.
Protein: UBP14_RABIT
Sequence: MPLYSVTVKWGKEKFGGVELNTDEPPMVFKAQLFALTGVQPARQRVMVKGGTLKDDDWGNIKIKNGMTILMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSAAAVAPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDIEDKKVNQQPNASDKKSSPQKEVRYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKHDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEENEQ
What is the function of this protein?
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.  Ensures the regeneration of ubiquitin at the proteasome.  Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell.  Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.  Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1 (By similarity).  Indispensable for synaptic development and function at neuromuscular junctions (NMJs) (By similarity).  Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: YD445_YEAST
Sequence: MFNVLLLPKLISFSNEIALLAQSVARMTLNHKVRGSSPLQGYLFFKQHPHFIVVIVIFLRNFYFIYDIFFYVYIINHQTHVAFSAPFDISPSLYSFDRSACDDWFGSSFGSFASSASSLQTLDPKWCSTMCSTAT
What are the official names of this protein?
Putative uncharacterized protein YDR445C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y465_STAA3
Sequence: MDSHFVYIVKCSDGSLYTGYAKDVNARVEKHNRGQGAKYTKVRRPVHLVYQEMYETKSEALKREYEIKTYTRQKKLRLIKER
What are the official names of this protein?
UPF0213 protein SAUSA300_0465.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: CRF1_ARATH
Sequence: METEKKVSLPRILRISVTDPYATDSSSDEEEEVDFDALSTKRRRVKKYVKEVVLDSVVSDKEKPMKKKRKKRVVTVPVVVTTATRKFRGVRQRPWGKWAAEIRDPSRRVRVWLGTFDTAEEAAIVYDNAAIQLRGPNAELNFPPPPVTENVEEASTEVKGVSDFIIGGGECLRSPVSVLESPFSGESTAVKEEFVGVSTAEIVVKKEPSFNGSDFSAPLFSDDDVFGFSTSMSESFGGDLFGDNLFADMSFGSGFGFGSGSGFSSWHVEDHFQDIGDLFGSDPVLTV
What is the function of this protein?
Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development.  Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor CRF1, Protein CYTOKININ RESPONSE FACTOR 1.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Relocalization from the cytoplasm into the nucleus is induced by cytokinins.
Protein: TIG_BACAA
Sequence: MAAKWEKLEGNVGVLTIEVDAKEVNNSIDAAFKKVVKTINVPGFRKGKMPRPLFEQRFGIESLYQDALDIILPKAYGEAIDEAGIFPVAHPEIDIEKFEKNANLIFTAKVTVKPEVKLGEYKGLAVEKVETTVTDEDVENELKSLQERQAELVVKEEGTVENGDTAVIDFEGFVDGEAFEGGKGENYSLAIGSGTFIPGFEEQVIGLKSGESKDVEVSFPEEYHAAELAGKPATFKVTVHEIKTKELPELNDEFAKEADEAVATLDELKAKLRTNLEEGKKHEAEHKVRDEVVELAAANAEIDIPEAMIDTELDRMVREFEQRLSQQGMNLELYYQFTGTDADKLKEQMKEDAQKRVRINLVLEAIIEAENIEVTEEEVTAEVEKMAEMYGMPVDAIKQALGSVDALAEDLKVRKAVDFLVENAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ARNT_ECOSE
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPPA2_PSEAB
Sequence: MRPRSALRYSLLLLAFAASAAIQAQPKTLAVCTEAAPEGFDPARYTSGYTFDASAHPLYNALAAFAPGSATVIPALAESWDVSADGLVYTFRLRQGVKFHSTDYFKPSREFNADDVLFSFQRMLDPQHPAHDLSPSGYPYADAMQLRDIIERIEKIDEHQVRFVLKHPEAPFLADLAMPFGSILSAEYAGQLIARGKGDELNSKPIGTGPFVFTRYRKDAQVRYAANPDYWKGKPAIDHLVLAITLDPNVRVQRLRRNECQIALTPKPEDVAALRQDPQLTVLEEAAMITSHAAINTRHEPFDDPRVRRAIAMGFNKSSYLKIVFGDQARPAIGPYPPMLLGYDDSIRDWPYDPERAKALLKEAGVAPDTPLNLYISTGSGPGGNPARVAQLIQSDLAAIGIRVNIHQFEWGEMVKRTKAGEHDMMLYSWIGDNGDPDNFLTHNLGCASVESGENRARWCDKGFDEAIRKARMSNDESQRVALYKEAQRIFHEQMPWLPLAHPLMFDAQRKNVSGYRMSPMSARDFSRVKLD
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).  Shows high flexibility on substrate recognition.  Efficiently uses tripeptides (PubMed:25338022).
What are the official names of this protein?
Di/tripeptide-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
Protein: PURL_CALMQ
Sequence: MGLTSDEAKIIINTLGRNPTEAEWLIFEAEWSEHCSYKSSRAWIRLLPSKSPLVIRGSGLDAPIIRINNIAVTFKIESHNHPSAVDPYDGAATGVGGIVRDILTTGLRPIALLDNLHLGSLDNQRSLWLSRNIIKGISDYGNRIGVPVVGGETWFDESFNNNPIVLVTCIGAGDFKRVIWGEGKVGDLVLVVGNDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLIDALMELGERGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELKPEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGFDLIGKLTNDGKFTAYYKGIKLIDLPLDLITNPPEPIRKYTEPVYLMRLRRIPPLPSVKFNEALIKVASSPNLASKEVIYTQYDYEVGVRTVIKPGRAGATVLRLLEEDGGDGKLGIAVKADSNPRYSYLNPFTGAANSLAKAYRNVASVGAKPIAAVDSINVGNPEKPDKYWYFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLGVVNDYAKAIEGGLTGEGWLVIIGDTGPELGGSEFLHSVHGLVAGEPPEPKPLSEVKNANLVMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDLSKAPLTQGLNDPVTVAFSETNARYIIETSNLKETVRIIEANGVPYGVLGESGGGIVQFKWGGLELASLSVDDLVSINDSLRGVI
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_VIBCM
Sequence: MANPKADRLIQFLTEQGITSPQVLAAIHALPREFFVAPAMMHQAYDNNALPIGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQWDAKRRLKQLDIYNVSTKHGDGWQGWPARGPFDAILVTAAAAKVPQSLLDQLAEGGRMVIPVGEDEQYLYKIVRQGGQFISERVEAVRFVPLVAGDLA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILF3_DANRE
Sequence: MPPPLRHRSMRIFVNDDRHVMAKHSAIYPTQEELEGVQNMVSHTERALKLVSDWLDDQEKGNAKVNALDTDGEGDKETEPSTGEQATRSLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTITLLKKVSDNLAVQLKQLVTEEKYDVKPCIRDATIVIKNAKEPPLTLTIHLTSPLVREEVEKQAAGETLSVIDPPDVLDRQKCLTALASLRHAKWFQARANGLRSCVIVIRILRDLCARVPTWSPLRGWPLELLCEKAIGTGNRPMGAGEALRRVLECLASGILMADGSGICDPCEKELTDAISHVDRQQREDITQSAQHALRLSAFGQLHKVLGMDPLPSKMPRKPRSDTPIDYTVQIPPSTTYVPPMKRPIEEESTDEKNPNKKKKKLQKKSPDEKAEPAQAMNALMRLNQLKPGLQYKLISQTGPVHVPVFTMSVEVDGKNFEASGPSKRTAKLHVAVKVLQDMGLPTGMDQKTTELMKVDEPVSTQETLPPVIKMEPEPVPITETPTDENARQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEIDGQKFQGTGSNKKVAKAYAALAALEKLFPEGSNSEVNKKKKMPPMHTGFGMVSGPPSDMMPNPRGRGRGRGRGRGRGFNNGGGFNQGGYGTYGYGGNNSGYNFYNNGGSNGGSVASNQGTNQSSGGAAATGGFGSYYQSDSSYTSPAPTPKPVGKKPPMHQNTKPQAPGVGQGGSYGQYNQGYGQKKNFGQTQGGGGAAAGGGGNFNYSTAYPSQVTGGQEYNYEGYSNQSNYNSQGGANQNFGGNSAPYNSGQAGYGRGDPNMNYQYR
What is the function of this protein?
RNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by back-splicing circularization of pre-mRNAs.  Within the nucleus, promotes circRNAs processing by stabilizing the regulatory elements residing in the flanking introns of the circularized exons.  Plays thereby a role in the back-splicing of a subset of circRNAs.  As a consequence, participates in a wide range of transcriptional and post-transcriptional processes.  Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (By similarity).  Upon viral infection, ILF3 accumulates in the cytoplasm and participates in the innate antiviral response.  Mechanistically, ILF3 becomes phosphorylated and activated by the double-stranded RNA-activated protein kinase/PKR which releases ILF3 from cellular mature circRNAs.  In turn, unbound ILF3 molecules are able to interact with and thus inhibit viral mRNAs.
What are the official names of this protein?
Interleukin enhancer-binding factor 3 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Nucleus.
Protein: P15_CILVC
Sequence: MLNWSTIEWDSFWQQHDCGCFTFECDFITSIDPLVHDYAIYHSLSQKTVLEMLQTHLVAGPDASETIRRQVAFLIYDFHRLSCNCDKCYGDCNATTTGRFKVVDRVLNDHIEFGIMRRQDLIPILHNLET
What are the official names of this protein?
Uncharacterized protein p15.
Protein: RCQ1_SCHPO
Sequence: MSSRALRKLQRQRQTELLEEALDSESDEDDEFSSTSGKKVVNVFEILEKENNAINSEAEKSVSEEEQDEPLVEGESPIVSTNKKAKNKKKKKKQQKKKKVTGKRDLDNQSSDNEKLEGLESSKNIDDDIDEIEKAAAELKLKYREQDQVEHVAGVEESATIPLDKELDEKLNKLLGVNISMLNPDLEIRKIFGRIVEKRSVNARHDNLRRKRHVLVQPQEGWPPLVRSGLGMKLTGQSQDLECFFEITQSRAYQEVQETFEYYVQTYDPNNLLMLLRSHPFHIDTLLQVSEIIDQQGDHELSAELVARGLYAFDSILHPRFNLATGATRLPFAIPSNRRLFLCIWRYLQSLQSRGCWRTVFEFCKALLQFDMSDPYAIGTCIDIYALRRREFAWIIDFANYLENSNKISDTPNMLYSSALAMFYVHGDTTDTRASMLAAFERAPYMLSELLDTLNISFTKSSIPSPQDPVQELHSAMYALYAKDSWSDPTVLAFINSILEKETVTLHDVEGQFAELTENLSRRVILLNEQSLRKFLPQRILQGTILSFDPLPPDTYLSESQVFGRDISRRIASFLSDYLSRAREVNENEEEPPAHEFDLPPAEQLLQQIESEVGEESEDGTPVMTRLRSFFGSLFTSTNSETEPAEESTEEMGQGD
What is the function of this protein?
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.  Rqc1 is essential for the recruitment of cdc48 to ribosomal subunits.
What are the official names of this protein?
Ribosome quality control complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCF25 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_CROS5
Sequence: MFCEQCEQTASGNGCHQWGACGKSPEVNAVQDLLVYCLRGLAPVTIKARELGISCHEADVFTGETLFATMTNVNFERKRFNVYIRQCIHIREGLKNSIEKISKKPISWSEVSNYQPNFSESLAEQGREKDLTFISQSTNNVDIFSLKLTVLYGIKGTASYTFHAQELGQEDEKVYAFIQEALASLDRNDLSLEDWVNIALKVGEINLRAMELLDQGHTTTYGHPTPTKVPLNPKQGKGILVSGHDIKQLAALLQQTVNKGLMVYTHGELLPAHGYPILKEKYPHFYGHYGTAWQNQTKDFAHFPGAIIVTTNCLMPPHETYEDKLFTIGPVGYSGINYLSSDDKGVPDYSLAIETSLKMAGFTTDEAPRHVMVGFAHNTVLNVSEQVIEAVKKGEIRHFFLVGGCDGAKPGRTYYTEFVEKVPKDCIVLTLACGKFRFFDKQLGEIGNLPRLMDVGQCNDAYSAIKIALGLAEAFQVSVNDLPLSMILSWYEQKAVAVLLTLLYLGIKDIRLGPTLPAFITPNVLRFLSETYNLQPITTPDQDLVACLA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SALDC
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HIS1_RIPO1
Sequence: MLTIAIPKGALLSDAIKLFQSIGLDFSAFLDPKNRQLQITDPTNTAKALLVRATDVPVYVEYGQAQLGIVGYDLLLEKTPTVANLANLKFGYCRMSVAVPASSPYKSPVELPPNGKVASKFVNCAKKYFHTLDLPVEIIPLYGSVELGPITGMSEAIVDLVSTGRTLKENGLIEIDTLFESTAHLIAHPLSYRLNLDQINPWVTKIRDTLS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_THET8
Sequence: MAKEKGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  Can inadvertently accommodate and process cysteine.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_CHLTE
Sequence: MSNSQSKKIFGLIGKHVDYSWSPLIHNTGFEALGLPCVYTIFNIPSPEMIGDALKGSRALGIAGFSVTIPYKKTVVPFLDELSPEALSIGAVNTIVNDNGRLLGYNTDIDGFAAPLLPMAESIRNRPVCIFGNGGAALAAVEAFRLRFNPSSVLLVVRDTQKAEDMLEEYAYRDLVTIHAGREIDQPACSKLIRDCRVLVNATPVGTAGRNDHIHSILPTGHGLLHDGQIVYDMVYNPPETPLLAEARAAGATVIAGIEMLIAQAARAFSIWTGQELPVDLVRKTVLAAIEKSEG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: M28P3_PHANO
Sequence: MRSSMFFAVCAAAALQTALSSPIHPRHAHQSFPNTEQWPIATVGKALKQQLPDEELQGILSQVSQDNIEATIRKLASFGTRHTLSSQTDPARGIGAARTWLTEQFQEAADASEGRMTVDWNSFVKYPGDNERIIFPVNITNIVTTLKGSEDPDRLYVTGGHYDSRNSNPIDYQGDAPGAVDVSNSCYTNWVWEDASGVAVSLELARIFAKYQPKTTIVFTAFAGEEQGLLGAENLAQTYKNNSVNVAGMINLDMVGNSKAEDGTSDPYNIRLFCQGTPLTENSTTTTSRLSIGGDNDSPARNLGRHIYEVASNAFTEMTVRLIYRLDRYSRGGDHRPFLEAGYTGVRFVQPNEDYTQQHQNVTVRNGKQYGDLVEWLDFEYNTRAAKVVASTMWSLANAPGEPMNVGINTTTSDNFSQFKWTAPKGLPVEGYEIVYRETLEPHWTSVIEVGDVNWYNLTSATIHKDNVIFGVRSVGKGGYRSPAVLPFPFGCTRNC
What are the official names of this protein?
Probable zinc metalloprotease SNOG_06590.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCD43_RAT
Sequence: MAAPSEVAAAVLGEGDGGGFGSWLDGRLEALGVDQAVYRAYILGVLQEEEEEEKLDALQGILSAFLEEDSLLDICKEIVERWSETRDVTTKVKKEDEVQAITTLIEKQAQIVVKPRVVSEEEKQRKAALLAQYADVTDEEDEADEKADPGASTANIGSDKSLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQREKDKLAKQERKEKEKKRTQRGERKR
What are the official names of this protein?
Coiled-coil domain-containing protein 43.
What is the protein family that this protein belongs to?
Belongs to the CCDC43 family.
Protein: VATB_TREDE
Sequence: MKKVYSKIESINGSVITVKADGVSYGELAEVQTRFGASLAEVNKLEGDLVSLQVFAGGRGVSTGDEVRFLGKEMQVSYSEDLLGRIFNGSGDPRDSGPALKDNMIPIGGPSVNPSKRILANRMIRTGIPMIDVFNTLVVSQKLPIFSSSGEPYNELLARIAMQAEVDVIILGGMGLKYDDYLYFKDTLEEAGALSRTAMFVHTAADPTVECLMIPDMCLAVAEKFAIAGKNVLVLLTDMTNFADAMKEIAIIQEQVPSNRGYPGDLYSQLAARYEKAVDFADAGSVTVLAVTTMPGDDVTHPVPDNTGYITEGQFYLKNGRIEPFGSLSRLKQNVNGKTRDDHRALMDNMIKLYASYKDTLEKKSMGFMMSEWDEKLLKYGAKFESGMMDLSVNIPLEDALNLGWKILAECFTREETGIKSELVNKYWPAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RIBY_CHLAA
Sequence: MMKLRVLTLGILIILLITACSAPTPTTPAAAPTAAPAPNAQPTLQQVTLAMSYIPNIQFAPYYVAAAKGYYAAEGIEVVFDYNFENDVLQRAATWPTSGVAFATTSGTSVLLARQQGLPVKTVMTLYQRFPIAFFAKSNVPLASVNDLRGQTIGIPGRFGESFYALLAALYAGGMSEADVTVQEIGFTQTAAVMEDKVPVAIGYAMNEPVQLRGQGVEVNVLLAADVFNLAANGIAVSEALIAQNPELVRKFVRASLRGLADTLANPDEAFDLSLQFIPEAQLGDLSLQRQVLQESLPFWQNELTAQYGLGYTDGQLWTRTEEFMRAAGLLSAPVDVQQAFTNEFVPGGSY
What is the function of this protein?
Part of an ABC transporter complex that transports riboflavin into the cell (PubMed:25938806).  Binds riboflavin (PubMed:25345570).
What are the official names of this protein?
Riboflavin-binding protein RibY.
What is the protein family that this protein belongs to?
Belongs to the NMT1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYQ_CLOP1
Sequence: MSNAEHSSNFIRNIIIDDLDSKKHDTIITRFPPEPNGYLHIGHAKSIVLNFELGKEFNGRTNLRFDDTNPTKEDTEYVESIKEDVHWLGYNWSELHFASNYFDEMYKRALLLIKKGKAYVCDLTPEEIKEYRGTLTEPGKESPYRNRSVEENLDLFERMRKGEFEDGSKVLRAKIDMSSPNINFRDPIIYRIAHASHHNTGDKWCIYPMYDFAHPLEDAIEGITHSICTLEFADHRPLYDWFVKECEMESVPRQIEFARLNITNTVMSKRKLKQLVDEGIVDGWDDPRMPTVAGLRRRGYTPKSIRNFCKAIGVAKADSTVDSQMLEHFIREDLQETAPRAMAVINPLKLVITNYPEGESEILEIENNPKDESAGKRAVTFSREVYIEREDFMENPPKKYFRLFPGNEVRLKGAYFVKCNEVIKDENGEVTEIHCTYDPETKSGTGFTGRKVKGTIHWVDANNCIPAEFRLYEPLILDDCEENEGKHFLEQINPNSLTICKGFIEPSAKDAKPQDKYQLFRHGYFNVDPNFTSDDNLVFNRIVSLKSSFKLK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG078_VACCC
Sequence: MDKLYAAIFGVFMGSPEDDLTDFIEIVKSVLSDEKTVTSTNNTGCWGWYWLIIIFFIVLILLLLIYLYLKVVW
What is the function of this protein?
Late protein which probably plays a role in virus entry into the host cell.
What are the official names of this protein?
Protein OPG078, Protein I2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG078 family.
Protein: VPR_HV2KR
Sequence: MTEAPAEFPPEDETPPRGPGDEWVIGILRELREEALKHFDPRLLTTLGNYICARHGDTLESARELINVLQRALFVHFRAGCKISRIGQTRGETPFSAIPTPRGMQ
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATP6_MACCJ
Sequence: MGHESPLYSLDLFGHEMIFDLSSMLMLTVTAAIVFLIAMLFTRNLSVRPHGKQNFIEWIFDFTRGIINSNMAWNKGGRFHFLAVTLLLFIFVANMLGLPFAIINGHTLWWKSPTADPTVTLTLSTLMVLLTHFYGVKMRGTGNYLKSFAQPVWFMVPFKIIEEFSSTLTLGLRLYGNIFAGEVLLGLLATLGTAGAAGMLGAAIPTLIWQGFSIFVGSIQAYIFVMLSMVYMSHKVSDDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.