PharMolix/UniProtQA huggingface dataset:
Protein: RS21_PSEPW
Sequence: MPAVKVKENEPFDVALRRFKRSCEKAGVLAEVRSREFYEKPTAERKRKAAAAVKRHAKKVQREQRRAVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PCDG5_HUMAN
Sequence: MASPPRGWGCGELLLPFMLLGTLCEPGSGQIRYSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTAGRIDREELCAQSPLCVVNFNILVENKMKIYGVEVEIIDINDNFPRFRDEELKVKVNENAAAGTRLVLPFARDADVGVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKETVHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLMLTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSLDYEESRFYLMEVVAQDGGALVASAKVVVTVQDVNDNAPEVILTSLTSSISEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIFSVTAHDPDSGDNARVTYSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALLDRDALKQSLVVAVEDHGQPPLSATFTVTVAVADRIPDILADLGSIKTPIDPEDLDLTLYLVVAVAAVSCVFLAFVIVLLVLRLRRWHKSRLLQAEGSRLAGVPASHFVGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLLSEESCEKSEPLLMSDKVDANKEERRVQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-A5, PCDH-gamma-A5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: QUEC_ACISJ
Sequence: MSRLPQRRALVLLSGGQDSATCLAWALARYGHVETLGFDYGQRHRVELDCRQRLIDGVRALPWPGQLGPDHMLTVDVLAQLGGSAMTDDVAIAMQADGLPNTFVPGRNLLFFTLAAALAYRRGLDVLVGGMSETDYSGYPDCRDSTLKALQVALSLGVDRPLTLETPLMWRSKADTWALAQRLGGDALVELIRCESHTCYLGQRGDLHAWGHGCGGCPACELRAQGWEQWTAQRSLNGA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL9_METS4
Sequence: MEVILLERVAKLGQMGETVKVRPGFARNYLLARGKALRATEANKKRFEDQRAQLEARNLERRTEAQAVAEKLDGQSFVLIRQSGETGVLYGSVSTRDLAEVLTQNGFTVGREQFSLNQPIKTLGLHNVPVVLHPEVEVTVTVNVARSPEEAERQARGESTTVRDELDLEELGLEVGAALAEAGPDAGER
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YFCN_SALHS
Sequence: MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPTRRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWQPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: IPMKB_ARATH
Sequence: MLKVPEHQVAGHIASDGKLGPLVDDQGRFFKPLQGDSRGEHEAKFYESFTSNMKVPDHIHRYFPVYHGTQLVEASDGSGKLPHLVLDDVVSGYANPSVMDVKIGSRTWYPDVSEEYFKKCIKKDRQTTTVSLGFRVSGFKIFDHQESSFWRAEKKLVLGYNADGARLALRKFVSSNSPADSNLTPNCAFASEVYGGCNGILAQLLELKDWFETQTLYHFNSCSILMIYENESILMQGGDDAPAPRAQVKLVDFAHVLDGNGVIDHNFLGGLCSFIKFIKDILQSVEKHDETDTSLLENGR
What is the function of this protein?
Inositol phosphate kinase with a broad substrate specificity.  Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4), inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) and inositol 1,2,3,4,6-pentakisphosphate (Ins(1,2,3,4,6)P5) but not inositol 1,4-bisphosphate (Ins(1,4)P2), inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), inositol 1,2,6-trisphosphate (Ins(1,2,6)P3), inositol 3,4,5,6-tetrakisphosphate (Ins(3,4,5,6)P4), inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5), inositol 1,2,4,5,6-pentakisphosphate (Ins(1,2,4,5,6)P5) or inositol hexakisphosphate (InsP6).  Involved in the auxin signaling pathway.  Regulates axillary shoot branching and is required for phytate synthesis in seeds.
What are the official names of this protein?
Inositol polyphosphate multikinase beta, Inositol polyphosphate 6-/3-/5-kinase beta, AtIpk2-beta, AtIpk2beta.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_CHLL2
Sequence: MDQLIQLVEATQSRTDFPVINPGDTVRIQLKVIEGEKERLQAYEGVVISDRGAGASKTITVRKISHGVGVERIIPVNSPNVESVTVLKHGKARRAKLFYLRKRTGKAALKVKERKFPVKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ARLY_CAMJ8
Sequence: MKNEMWSGRFSGASDELLKEFNASLNVDKTLFNEDIQGSIAHATMLESCGILKKEELDAIIKGLEQVKSEIEQGKFVFDIKDEDIHMAIEKRLSEIIGSEIGGRLHTARSRNDQVATDFKLFVKKSHIELLKLLKELIQTMLEHAKVHKKTIMPSFTHLQHAQPVSFSFYILAYAFMLMRDIKRLQNSLELADFSPLGSCACAGTSYATNRELSAEILGFKDIMPNAMDGVSDRDFALDLLYDIAVIFTHTSRLCEEMILFSSSEFSFITISDSFSTGSSIMPQKKNPDVCELIRGKTGRVYGNLISLLTIMKALPLAYNKDMQEDKEGLFDSVKTAKDSLIILNAMLKEIQINKENMLNACKKGHLLATDLADYLVREKNIPFRKAHFIVGNVVAQAEAQGIDISEIKDLSKIDPVFDEKAMELLNFEFSLNSKQSEGSSSIASVEKQIQILEGFIQNL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDPS4_ARATH
Sequence: MLSMLWFLLSLLSLLLLPCLRPCFPAKGSLKNKKKIDKGTYVVGEEETPKELQRELMPRHVAVIMDGNRRWAKQTGLLTSQGYEAGAKRLLEFADLCFKLGINTVSAFAFSTENWGRHKIEVKCLMYLFQRYLKSKIQFFQSKEIRVSVIGNLAKIPESLLRTVHELEEATKSYKKKHLILAIDYSGRFDILGACKNIVKKSEQGLIREEDVDETLFERELQTRCTEFPSPDLLIRTSGEQRISNFFLWQLAYTEFFFSPVLWPDFDKQKFIEALVSYQRRDRRFGSRL
What is the function of this protein?
Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase 4, Dedol-PP synthase 4.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: THYX_MYCSJ
Sequence: MAETAPLRVQLIARTEFTVPPDVPWETDAEGGAALVEFAGRACYQSWSKPNPRTATNASYLRHIIEVGHLSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPENDSQVVVPPGIEGDAELEGLFTAAADASRAAYAELLAKLEAKLMGDEPREGRATLRRKQARQAARSVLPNATETRIVVTGNYRAWRHFIAMRASEHADLEIRRLAIACLRELVAVAPAVFADFEIYPLADGTEVATTPLVTEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: COAA_BRUA1
Sequence: MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRLIHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINMKNLNENILPTRPRADLILRKGSDHLIEEVALRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5N3BA_XENLA
Sequence: MRLPVLGKDTVRMRDPEGLQDKITRIQRGGQEKLQIISDFDMTLSRFSRNGERCPTCYNIIDNSNIISDEGRKKLKCLFDIYYPLEIDPKKSIEEKYPLMVEWWSKAHDLFYEQRIQKDRLAQVVKESQATLRDGYDLFFNSLYQREIPLFIFSAGIGDVLEEIIRQAGVFHPNTKVVSNYMDFDDNGILTGFKGDLIHTYNKNSSVLKDTEYFKEISHRTNILLLGDTLGDLTMADGVSTVENIIKIGFLNDKVEELTEQFLQSYDIVLLRDETLDVVNGILQFVTAKN
What is the function of this protein?
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate.  The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids.  Also has weak activity for CMP.  UMP and purine nucleotides are poor substrates (By similarity).
What are the official names of this protein?
7-methylguanosine phosphate-specific 5'-nucleotidase A, 7-methylguanosine nucleotidase A, Cytosolic 5'-nucleotidase 3B-A, Cytosolic 5'-nucleotidase III-like protein A, cN-III-like protein A, N(7)-methylguanylate 5'-phosphatase A.
What is the protein family that this protein belongs to?
Belongs to the pyrimidine 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTDC_HUMAN
Sequence: MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
What is the function of this protein?
Although its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LIGB_CITK8
Sequence: MRRGKSIVLSLLLWHFPVWAACPDWSPARANDEIARLQQQLAQWNDSYWQQGVSAVDDSVYDQLSAQLVQWQRCFGGDTGAELAPPVSGSLPHPVPHTGVRKLADKQAVQQWMRKRSDLWVQPKVDGVAVTLVYRDGRLVSAISRGNGLKGEDWTQKVRLIPAVPQSTKGALANSTLQGEIFLLHDNHIQRQMGGMNARSKVAGMMMRQNNTSSLQSLSVFIWAWPDGPATMPERLRQLSGAGFGFAQQYSQPVKSADDVERVRTAWWTTGLPFVTDGVVVRTGKEPEARHWMPGQGDWLVAWKYPPVAKVAEVTGVQFAVGKSGKISVVASLAPVMLDDKRVKRVNVGSVRRWEEWDIAPGDHILVSLAGQGIPRIDKVVWRSTQRDKPAPPGNRYNALTCFYATEVCQEQFIARLVWLGSKEALEVDGMGEAGWRVLHQAHRFEHIFSWLALTQEQLQATPGFSKEKSKQLWHQFNLVRHRPFIRWVMAMGIPLTQGALKANGDRSWGQLLARTAEYWQQLPTTGEGRARRVIQWRDNPEIRALGNWLAARHINGFSP
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: MTG1_SCHJY
Sequence: MTTWFPGHMKTTLKRLRDSVSKNDVIVEVRDARIPLSSRNPALETLAANRKRVVVYNKCDLAFPSAGDLCKTRALNSVRAFEETYVETLARWETIQTLRRYVGTVSNVPECIKRLLQLLQKLTYSDHAASNRTVKVFVVGMPNVGKSSVMNALRHASLHRRKVAVVGSHPGVTRNVGEVVRLFEGKNVYMVDTPGIMLPTILQPEDAIKFALVHAMKDGRLHNAVVVDYLLYRLNLIDPNTYTRLSSPTNDVSTFLHNAAVHTGKLGKGGTVNDDLIASYVLQLYRTGFFGAFVLDSMEEEQWQQRLALEKNLVRRNQRRVCSTRKKA
What is the function of this protein?
Mitochondrial GTPase involved in assembly of the large ribosomal subunit (By similarity).  Plays a role in expression of the mitochondrial translational machinery (By similarity).
What are the official names of this protein?
Mitochondrial GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: CUPP_DROME
Sequence: MYLLVNFIVALAVLQVQAGSSYIPDSDRNTRTLQNDLQVERDGKYRYAYETSNGISASQEGLGGVAVQGGSSYTSPEGEVISVNYVADEFGYHPVGAHIPQVPDYILRSLEYIRTHPYQIKDYYTGELKTVEHDAAAFNVYTRNIQDHTIPQSRPSTTPKTIYLTHPPTTTSRPLRQRRALPTH
What is the function of this protein?
Component of the cuticle of the pupa of fruit fly.
What are the official names of this protein?
Pupal cuticle protein.
Protein: BIOF_RIPO1
Sequence: MSYQWLEKALKTIHQANWYRSVTAITSLPGSTIEIDGNTFINFASNDYLGLAGDPRLIKAAVEATQQFGTGSTGSRLLSGHRELHQELETAIASLKQTEEALVFSSGYLANLGTITAIVGTRDLILGDQYNHSSLKNGSKLSSATVLEYDHCNSEDLQEKLQQHRHQYRRCLIITDSIFSMDGNACPLQKLLSLAADFDCMLLVDEAHATGVIGETGAGLVEHFGCSNQPLIMTGTLSKALGSLGGYVAGSRMLIDFLRNRAPTWIYTTGLSPADTSAALEAIKIMQNEPQRRKKLWDNVNYLKEKLCDFNLFTSDSPILCLGIETVEKALTLASQLKEKGIFVPAIRPPTVPTSRLRFSVMATHEETQLQQLVTTLNQLI
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: NUP43_HUMAN
Sequence: MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHYHTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLGPCLVCGTDAEAIYVTRHLFS
What is the function of this protein?
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC).  The Nup107-160 subcomplex is required for the assembly of a functional NPC.  The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.
What are the official names of this protein?
Nucleoporin Nup43, Nup107-160 subcomplex subunit Nup43, p42.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Protein: COAX_CLOBH
Sequence: MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKYFNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDALFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDEINAILTLEGLRVIYEKNK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_RHOP2
Sequence: MQVLVRDNNVDQALKALKKKMQREGIFREMKLRGHYEKPSEKKAREKAEAVRRARKLARKKLQREGLLPMKPKPAFGAERGRPGAGGPGAGGPGAGPRGPR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RIMP_SHEFN
Sequence: MATIESKLVEMLTVPVEALGFKLWGIEYIQAGRHSILRVFIDHENGINIEDCAEASRQVSAVMDVEDPISTEYTLEVSSPGVDRPLFTAEQYRAYIGEETKVQLTMPVAGSRNLKGVISSVDGQMLTITVDGKDLIVALDNIRKGNVIAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_RAT
Sequence: MAADSQTPWLLTFSLLCLLWPQEAGAFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKEEAQQRTDMELLRFSLLLIQSWLGPVQFLSRIFTNSLMFGTSDRVYEKLKDLEEGIQALMQELEDGSPRIGQILKQTYDKFDANMRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFAESSCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FEN_PICTO
Sequence: MGVNLSSILIKHETSLKDNSGSIVSVDAYNIIYQFLSSIRGDDGEPLKDSNGNITSHLSGIFYRTSNLLENNIKPVYVFDGKPFHLKSETLRERSLIKEKNIMKLEEAIASNDDAKIRSLSSRINYITDDIVNESKTLLNLMGLPYVQAPSEGEAQASYMTLKGDVNAVVSQDYDCLLFGAKRILRNFTVYGRRRIAGTSRTINVNPEIIDLNENLSNLGISREQLIYIGILTGTDFNPGVKGIGAKTALSLIKKYNDIYSVIKIKNIGIDNLDEIIEFFMNPPHNDYEIKFNEPDFDGIIDFLCGKHNFSESRVNETLEKISRNYKKDHQSSLDRFF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: B2MG_SAGMN
Sequence: MARFVVVPLFVLLSLFGLEAIQHPPKIQVYSRYPADNGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFSTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NLTP3_PEA
Sequence: MARSMKLACVVLAMCMLVAPMAEAAFSCATVMTDLRPCLTYLEAANNASPSPPCCAGVKNLQAAAPTVADRQAACNCLKSTAGAISNLNANNAAALPGKCGVNIPYKISASTNCNTIRF
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 3, PsLTP1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: RECA_RHIL3
Sequence: MSQNSLRLVEDKSVDKSKALEAALSQIERSFGKGSIMKLGSNENVVEIETISTGSLGLDIALGVGGLPRGRIIEIYGPESSGKTTLALQTIAEAQKKGGICAFVDAEHALDPVYARKLGVDLQNLLISQPDTGEQALEITDTLVRSGAVDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGAVKEREEVIGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELVDLGVKAGIVEKSGAWFSYNSQRLGQGRENAKTFLRDNPDLAREIELSLRQNAGLIADRFLQNGGPDPDDGDGDATAEM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYUG_MACFA
Sequence: MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGTKTKENVVHSVTSVAEKTKEQANAVSEAVVSSVNTVAAKTVEEAENIAVTSGVVRKEDLKPSAPQQEGEAAKEKEEVAEEAQSGGD
What is the function of this protein?
Plays a role in neurofilament network integrity.  May be involved in modulating axonal architecture during development and in the adult.  In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity).  May also function in modulating the keratin network in skin.  Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
What are the official names of this protein?
Gamma-synuclein.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle (By similarity).
Protein: PPOC_ORYSJ
Sequence: MAAAAAAMATATSATAAPPLRIRDAARRTRRRGHVRCAVASGAAEAPAAPGARVSADCVVVGGGISGLCTAQALATKHGVGDVLVTEARARPGGNITTAERAGEGYLWEEGPNSFQPSDPVLTMAVDSGLKDDLVFGDPNAPRFVLWEGKLRPVPSKPGDLPFFDLMSIPGKLRAGLGALGVRAPPPGREESVEDFVRRNLGAEVFERLIEPFCSGVYAGDPSKLSMKAAFGKVWRLEDTGGSIIGGTIKTIQERGKNPKPPRDPRLPTPKGQTVASFRKGLTMLPDAITSRLGSKVKLSWKLTSITKSDNKGYALVYETPEGVVSVQAKTVVMTIPSYVASDILRPLSSDAADALSIFYYPPVAAVTVSYPKEAIRKECLIDGELQGFGQLHPRSQGVETLGTIYSSSLFPNRAPAGRVLLLNYIGGSTNTGIVSKTESELVEAVDRDLRKMLINPKAVDPLVLGVRVWPQAIPQFLIGHLDHLEAAKSALGKGGYDGLFLGGNYVAGVALGRCVEGAYESASQISDYLTKYAYK
What is the function of this protein?
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
What are the official names of this protein?
Protoporphyrinogen oxidase, chloroplastic, PPO, Protoporphyrinogen oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVC_CERS5
Sequence: MRVYYDRDCDINLIKDKKVAILGYGSQGHAHALNLRDSGAKNVVVALREGSPSAKKAEAEGLKVMGIAEAAAWCDLIMFTMPDELQAETYKKYVHDNLKEGSAIAFAHGLNVHFGLIEPKPGVDVIMMAPKGPGHTVRGEYVKGGGVPCLVAVHNDATGKAMEIGLSYCSAIGGGRSGIIETNFRQECETDLFGEQAVLCGGLVELIRMGFETLVEAGYEPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRILPYEETKARMKAVLTDIQTGKFVRDFMQENAVGQPFFKATRRINDEHQIEKVGEKLRGMMPWISKGKMVDRARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MRAZ_SERP5
Sequence: MFRGATMVNLDSKGRLAVPTRYRELLNEQSEGQMVCTIDLHQPCLLLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDSAGRLLLATTLRQHAGLTKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.