PharMolix/UniProtQA huggingface dataset:
Protein: SYP51_ARATH
Sequence: MASSSDSWMRAYNEALKLSEEINGMISERSSSAVTGPDAQRRASAIRRKITIFGNKLDSLQSLLAEIHGKPISEKEMNRRKDMVGNLRSKANQMANALNMSNFANRDSLLGPDIKPDDSMSRVTGMDNQGIVGYQRQVMREQDEGLEQLEGTVMSTKHIALAVSEELDLQTRLIDDLDYHVDVTDSRLRRVQKSLAVMNKNMRSGCSCMSMLLSVLGIVGLAVVIWMLVKYM
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-51, AtSYP51.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Protein: RNH_RICCK
Sequence: MNENISKVVIYTDGACAGNPGPGGWGALLQFNDTSKEILGYELDTTNNRMEITAALEALRILKKSCNVEIYTDSKYLQQGITTWIHNWVKNNWCKSNNEAVKNADLWQKLYAELSKHTIIWKWVKGHANNSGNIAADKLAAQGRQTAIEILKCRV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUO_KOCRO
Sequence: MTDQRTLGSETAIERDVVVVGAGPAGLMAARTLVAAGRTVAVLEARDRVGGRTWSKTVDGAFLEIGGQWISPDQTELLALVDELGLETYQRYREGESVYLAPDGTRHTYTGSMFPAGESTIVEMEKLVALLDGLVAEIGATEPWAHPAARELDTISFHHWLRQHSDDEAACSNIGIFVAGGMLTKPAHAFSVLQAVLMAASAGSFSNLVDEDFILDRRVVGGMQSVSETMAAELGEDVVFLDTPVRTIRWAGDGGTYAEHVPGTPVTVWSDRLTVRAKDVVVAVPPNLYSRISFEPPLPRLQHQMHQHQSLGLVIKVHAVYETPFWRDKGLSGTGFGAHELSQEVYDNTNHGDPRGTLVGFVSDERADELFGLPAEERRRLILESLSHYLGEEALHPVVYYESDFGSEEWTRGAYAASYDLGGLHRYGAHQRTPVGPIRWACSDLAAEGYQHVDGALRQGRLAAAEVLGAGSLTGAER
What are the official names of this protein?
Putrescine oxidase.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: ADT1_MOUSE
Sequence: MGDQALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (PubMed:31618756, PubMed:31341297).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31489369, PubMed:31341297).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis (PubMed:31341297).  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A4/ANT1 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) (PubMed:31341297).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (PubMed:31341297).  Probably mediates mitochondrial uncoupling in tissues that do not express UCP1 (PubMed:31341297).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (PubMed:31489369).  It is however unclear if SLC25A4/ANT1 constitutes a pore-forming component of mPTP or regulates it (PubMed:31489369).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (PubMed:31618756).
What are the official names of this protein?
ADP/ATP translocase 1, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle isoform T1, Adenine nucleotide translocator 1, ANT 1, Solute carrier family 25 member 4.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A4/ANT1 is expressed in mitochondria (PubMed:11809823). May localize to non-mitochondrial membranes (By similarity).
Protein: RBL_CERSK
Sequence: MDTKTTEIKGKERYKAGVLKYAQMGYWDGDYVPKDTDVLALFRITPQEGVDPVEAAAAVAGESSTATWTVVWTDRLTACDSYRAKAYRVEPVPGTPGQYFCYVAYDLILFEEGSIANLTASIIGNVFSFKPLKAARLEDMRFPVAYVKTYKGPPTGIVGERERLDKFGKPLLGATTKPKLGLSGKNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLYVMEAVNLASAQTGEVKGHYLNITAGTMEEMYRRAEFAKSLGSVIVMVDLIIGYTAIQSISEWCRQNDMILHMHRAGHGTYTRQKNHGISFRVIAKWLRLAGVDHLHCGTAVGKLEGDPLTVQGYYNVCREPFNTVDLPRGIFFEQDWADLRKVMPVASGGIHAGQMHQLLSLFGDDVVLQFGGGTIGHPMGIQAGATANRVALEAMVLARNEGRNIDVEGPEILRAAAKWCKPLEAALDTWGNITFNYTSTDTSDFVPTASVAM
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RL40_LEITA
Sequence: MQIFVKTLTGTTIALEVEPSDTIENVKAKIQDKEGIPPDQQRLIFADKQLEEGRTLSDYNIQKESTLHLVLRLRGGVMEPTLVALAKKYNWEKKVCRRCYARLPVRATNCRKKACGHCSNLRMKKKLR
What is the function of this protein?
Component of the 60S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-60S ribosomal protein L40.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [60S ribosomal protein L40]: Cytoplasm.
Protein: FDHB_WOLSU
Sequence: MESQARVKFYCDEARCIDCHGCDVACKEAHHLPVGVNRRRVVTLNEGLVGKEKSLSIACMHCSDAPCAQVCPVDCFYVRADGIVLHDKEKCIGCGYCLYACPFGAPQFPKSGIFGSRGPMDKCTFCAGGPEETHSEKEYKLYGQNRIAEGKVPVCAAMCSTKALLAGDSDSISLIIRERVLKRGSGTASVPYTWSQAYKD
What is the function of this protein?
This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters.
What are the official names of this protein?
Formate dehydrogenase iron-sulfur subunit.
Protein: MSRA_PSEA8
Sequence: MVLRSEILTKKSELPTPDQALPGRESAMPVPEAHFVNGRPLTAPFPAGLQQVLFGMGCFWGAERRLWQQPGVWVTAVGYAGGYTPNPTYDEVCSGLTGHSEVVLVVYNPQETSFEQLLKVFWEAHDPTQGMRQGGDIGTQYRSVIYTFDAAQKAAALASRESFQAELAKAGYDRITTEIADVPPFYYAEAYHQQYLAKNPNGYCGLGGTGVCLPA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CINA_BACAC
Sequence: MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKETIASSLAEELVYDEKALASISDYFKRTGREFTENNKKQALVLDGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMKPMYVSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNVDEAEKLIQHVEDLILERVGGFFYGYDQEFLHDKAIVLLKKKGLTLACAESLTGGLFGNQVTESAGVSSVFKGGVICYHNDVKQHVLHVPEEVLFTDGAVSKECARYLAENVKELLEADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKYGFYHLYKKLEEI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: IL13_LAMGL
Sequence: MALWLTVVIAFTCIGGLASPVPTPSPKALKELIEELVNITQNQKAPLCNGSMVWSINLTTSMYCAARESLINITNCSVIQRTQRMLNALCPHKLSAKVSSEHVRDTKIEVTQFIKTLLQHSRNVFHYRSFNWSKKS
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection.  Synergizes with IL2 in regulating interferon-gamma synthesis.  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (By similarity).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6.  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
What are the official names of this protein?
Interleukin-13, IL-13.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAN_METVS
Sequence: MTYPDDYSTDVQKNEMDLKEFKEKAYLAELESKVLRLELKNKDITRENVQIKKENEILKRELDKLRIPPLILGTVLDRVNERKAVVKSSTGPNFLVNLSQFVEPDDIVPGARVCLNQQTLAVVEVLPKEKDYRAMAMELEEKPDILFGDIGGLNNQIRDIKEVVELPLKNPELFEKVGIVPPKGVLLYGPPGTGKTLLAKAVARETNASFVRVVGSELVKKFIGEGAKLVRDVFKLAKEKSPCIIFIDEIDAVASKRTESLTGGDREVQRTLMQLLAEMDGFDSRGDVKIIAATNRPDILDPAILRPGRFDRIIEIAAPDEDGRLEIFKIHTDKMNIKSVDLREIAKMAENMVGADIKAVCTEAGMFAIREGREYVTTKDFKEALLKVTGKKEKSEEGIAHLTTMYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_CHLPD
Sequence: MALPPTEVHHIRNFCIIAHIDHGKSTLADRLLEITNTLDRSQMSSAQVLDDMDLERERGITIKSHAVQMKYRASDGLDYTLNLIDTPGHVDFSYEVSRSLAACEGALLVVDATQGVEAQTIANLYLALDAGLEIIPVINKIDLPSSDVEGVARQIIDLIGIKRDEILQVSAKAGIGVYELIEAIVKRVPAPSDNKHLPLRALIFDSVFDIYRGTVAYLRIVDGVLKKGDKVRFFANNKVFLADEIGTMSLKRQPSAVLEAGDVGYLICSIKDVKDAKVGDTVTLSDSPALEALAGYKEVKPMVFSGLYPVNSNEFEDLRESLEKLALNDASLIYTPETSVALGFGFRCGFLGLLHMEIIQERLEREYGVNIITTVPNVEYRVILTNGDVVIVDNPSKMPDTSRIGDVEEPYVSMQIITLSDYIGNIMKLGMERRGEYKNTDYLDSTRVNMHFEFPLAEIVFDFHDKLKSISKGYASMDYEYIDYRQSDLVKLDVLLNAEPVDALSIIVHRSKAYEWGRKLCTKLKGIIPKQMYEVAIQAAIGSRVISRETISAMRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGRVEIPQEAFLAILTIDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CDIB_DICD3
Sequence: MFVSSRKTGLIVCFSLIGYTASAFSASLNPAERNETQQRQSEVIEQSRQQREALQQLNNIVQAPLKADNALQGPCFTLREIRFNHSTLLGQRDQTALTAGYLNRCNNLEQINQLMHDVSNWYIQRGYITSRAFLSEQDLSGGVLQLEILEGRLEKITINNQTERMTRTAFPAREGEILNLRDIEQGMEQMNRMPSQQVTIEILPGSQPGYSVVNLTREAHLPFTGGVTFDNSGQKSTGEQQLNGSLALDNLFGVADQWFISAGHSSRFATSHDAESLQAGFSMPYGYWNLGYSYSQSRYRNTFISRDFPWHSTGDSDTHRLSLSRVVFRNGTMKTAIVGMLSQRTGNNYLNGTLLPSSSRKLSSVSLGVNHSQKLWGGLATFNPTYNRGVRWLGAETDTDKSADEPRAEFNKWTLSASYYYPLTDSITYLGSLYGQYSARALYGSEQMTLGGESSVRGFREQYTSGNRGAYWRNELNWQAWQLPVLGNVTFMAAVDGGHLYNHKQDDSTAASLWGGAVGVTVASRWLSQQVTVGWPISYPAWLQPDTVVVGYRVGLSF
What is the function of this protein?
Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of CdiA.
What are the official names of this protein?
Outer membrane transporter CdiB.
What is the protein family that this protein belongs to?
Belongs to the TPS (TC 1.B.20) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CRVP_HELAG
Sequence: MEWYPEAAANAERYTQIVWYK
What is the function of this protein?
Helicopsin exhibits robust neurotoxic activity as shown by immediate death (about 8 minutes) of mice due to respiratory paralysis.
What are the official names of this protein?
Helicopsin.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHEB2_GEOSL
Sequence: MKKIKVLIVDDSAVVRQTMADILASDPQIEVMATAADPFIAAERMKSDVPDVITLDVEMPRMDGITFLQKIMSQHPIPVVMCSTLTENGSETAMKALEYGAVEIIQKPKLGTKQFLEESRVRICDAIKAASQARLRKIPARPHAVAPKLSADVILEKPASRAMIQTTERVVVVGASTGGTEALRVFLESFPADCPPIVIVQHMPEGFTRAFAQRLDGICRISVKEAADNDSVIRGRALIAPGNRHMLLKRSGARYYVEIKDGPLVSRHRPSVDVLFRSAARYAGKNAVGVIMTGMGDDGASGMREMKDAGAMTIAQDEASCVVFGMPNEAIKRGGTVKVLPLESIAADVIRHCS
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1079_LISMF
Sequence: MEYSYPLNPDWTTEEMTIVVQFLEAIERAYEKGIDTLELKEKYRAFKQVVPAKGEEKRIGIDFEKASGYSAYKVMQLVKNATTSKIKMQP
What are the official names of this protein?
UPF0223 protein LMOf2365_1079.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: CATA2_RICCO
Sequence: MDPYKFRPSSSNDTPFWTTNAGDPVSNNNSSMTVGPRGPILLEDYHMIEKLANFTRERIPERVVHARGMSAKGFFEVTHDVTDLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFATKFYTREGNFDIVGNNFPVFFIRDGIKFPDVVHAFKPNPKSHIQEYWRIFDFCSHHPESLSTFAWFFDDVGIPQDYRHMEGFGVHTYCLINKAGKVTYVKFHWKPTCGVKCLMDDEAIKVGGANHSHATQDLYDSIAAGNFPEWKLMIQTMDPADEDKFSFDPLDMTKIWPEDMFPLHPVGRLVLNRNIDNWFAENEMLAFNPAHVVPGVYYSNDKLFQLRLFAYSDTQRHRLGTNYLQLPVNAPKCPYHNNHYDGFMNFMHRDEEVDYFQSRYDPVRHAEKVPIPNAICSGRREKCVIEKEDNFRQPGDRYRSWAPDRQERFLCRLVNALSEPRITHEIRSIWVSWWTQCDKSLGQKLASRLNVRPNI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: RBCR_NEOYE
Sequence: MTDLPFTLDQLRILKAIAKEGSFKKAANSLYVSQPAISLQIQNLERQLNVSLFERGNKKATLTEAGSLLLRYGGRILALCEETCRALDDLQNLQGGTLIIGASQTTGTYLMPRLIGLFRQRYPQVAVQLQVHSTRLISWSVANGQVDLAIIGGEVPTELQDVLQVTSYAEDELALILPKSHPFSKLGDIQKEDLYRLRFIALDTQSTIRKVIDKVLSQHGIDSSRFKIEMELNSIEAIKNAVQSGLGAAFVSVSAIAKELELGIVHWAQIENVTIKRMLSIIVNPNRYKSKATETFSQEILTLFVTPSQHKILSDKL
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3SXQ_OPHHA
Sequence: MKTLLLTFLVVTIVCLDLGYTLICHQVHGLQTCEPAQKFCQKRTTMFFPNHPVLLMGCTYNCPTERYSVCCSTDKCNK
What is the function of this protein?
This three-finger toxin binds and inhibits the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Short neurotoxin SNTX26, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJL9_YEAST
Sequence: MNHLTTVLAARKTCVVREATNLYTVDTERRINKMGRDEEKKWRSRGGHWCMDDSIIQFTTFNQSCTLMGSTTATRANNETEKHEAITVFFVVFLYINKASVKFFFFA
What are the official names of this protein?
Putative uncharacterized protein YJL119C.
Protein: CP21A_FELCA
Sequence: MLLLGLLLLTALAGARLLWNKWKYRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKLGPVYRLRLGLQDVVVLNSKRTIEEALIRRWVDFAGRPQMPSYKLVSQHYQDLSLGDYSLLWKAHKKLTRSALLLGIRNSMEPLVEQLTQEFCERMRAQAGTPVAIQKEFSFLTCSVICCLTFGDKEDTLVHAFHDCVEDLMKSWEHWSIQVLDIVPFLRFFPNPGLRRLKQALENRDRIVEKQLRQHKDSMVAGQWRDMTDYMLQGMGKPKVEKGHGRLLEGHVHMSVVDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDCELGPGASGSRVPLKDPSRLPLLTATIAEVLRLRPVVPLALPHRTTRHSSILGYDIPEGTVVIPNLQGAHLDDTVWEQPHEFRPDRFLVPGASPRVLAFGCGARVCLGEPLARLELFVVLARLLHAFTLLPPTGPLPSLRPRSHCGINLTMQPFQVRLQPRGAVAPGPSQHQ
What is the function of this protein?
Specifically catalyzes the 21-hydroxylation of steroids.  Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
What are the official names of this protein?
Steroid 21-hydroxylase, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: FII_LAMBD
Sequence: MADFDNLFDAAIARADETIRGYMGTSATITSGEQSGAVIRGVFDDPENISYAGQGVRVEGSSPSLFVRTDEVRQLRRGDTLTIGEENFWVDRVSPDDGGSCHLWLGRGVPPAVNRRR
What is the function of this protein?
Plays a role in virion assembly by joining the head and the tail at the last step of morphogenesis.  Six FII proteins probably bind protein W that closes the DNA-filled capsid, as well as the U tail terminator protein of the pre-assembled tail.
What are the official names of this protein?
Head-tail connector protein FII, Head-tail joining protein, Minor capsid protein FII.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RRF_KLEP3
Sequence: MISDIRKDAEIRMEKCVEAFKNQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSAAVEKAIMASDLGLNPSSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKEKEISEDDDRRSQDDVQKMTDAAIKKVDAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35A_MOUSE
Sequence: MSGRLWCKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).  Required for the proliferation and viability of hematopoietic cells (By similarity).
What are the official names of this protein?
60S ribosomal protein L35a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_DELAS
Sequence: MALYCIGDIQGCHDAFERLLHRVDFSASRDTLYILGDLVNRGPESDKVLRTCMAAGDSMRALLGNHDLHLLAAAQGVRRSSRRDTLARVLDAPDRDQLLDWLRHQPLARSHRMAHGEELLMVHAGVLPQWSSQEVMALAGEVHSVLRSKQLPDFLQAMYGNQPDRWSPDLQGWERLRVIVNALTRLRFCTAQGVMDFDSTESAEQAAPGLMPWFDVPGRATASATIAFGHWSTLGHISRPDLVALDTGCVWGGCLSMMRFGDHLADRELIQVDCPQAQAPG
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: NDHI_NUPAD
Sequence: MFPMVTGFMNYGQQTVRAARYIGQSFMITLSHANRLPVTIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTVRTIMNSTQIKISMDKSLDSRTITN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: EDC1_ASHGO
Sequence: MSSDTMFINSARLLPTENRKVKQLQRPDRKKHTRGSYAAQKQQLPNGEQPNFGHGQKQSRKRGSGRQKGRDGAAGDSANVGLTEDLKQLLSIPSGSAGSESAQKETSAGQPATGAVADRKRSVPAGGPAGKSSSEPASASSAVDGMPGLGFQSAHVPFSSPVVNHPMLAEPAATGPVLSVPFPGHVAGYMPCVNNTRVQYPLQTRNNVPMSQPMSQPMSQPMSQPMSQPMSQPISPYLPQGFQMHPQSFVGLPVAPMYPQYMSAQYQSPKQQSACQMPLRAQPPLIPSITRNALPCVSSANSTAKASVRSKGSPGSEGGSRRSQNWKSSQNVGYAGATFATDQPALSSLPKPSFV
What is the function of this protein?
mRNA-binding protein which stimulates mRNA decapping.
What are the official names of this protein?
Enhancer of mRNA-decapping protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDC family.
What are the subcellular locations of this protein?
Cytoplasm.