PharMolix/UniProtQA huggingface dataset:
Protein: FANCA_MOUSE
Sequence: MPGSPARGAAMGGGPRGLRKTWTELLAGRVKKQKYDPEREQKLKDSALKLLRYHQNMHDLLLEVEEPQCKRLRLSELIDRDSADASSDRSASFIRSAFRDQASRLGVPVGVLSAKVFARSVQQVCVEPSHPVLLSPEQSKKLSSLLMIARHLLAQNMFSRLTFCQELWKAQNSLLLEAMWRLHTHSVVSLQELLQSHPDSEAMAMWLFRNLRSLCEQIGASCPSPDTTEAMLSGLVQLLISRGFQGSSDPRRLVEPERLPQVATDVLQRMLAFSLDTLEADPQTTLDCQAVSGWIPIYSGHTCCGVVTENSLKSFFSHTLTQILTHKPVLKVSDAIQMQKEWSFAKTHHLLTDLHCRVLATLGPEESVGRLQEVLEMQEVNWQHVLSCVSTLVVCFPEAQQLVKGWVASLMARAFESYHLDSMVTAFLIVRQATLEGPYVFPSYADWFKESFGSSHGYHSCSKKTLVFLFKFLSDLVPWEAPRYMQVHIFHPPLVPSKYHSLLTDYISLAKTRLADLKVSLENVGLYEDLSSPGDIAERESQAVQDVKKAIMVFEQTGKIPMPVLEASIFRRPYYVSHFLPTLLAPRVLPEVPDPRVALIETLKRADKIPSSIYDAYRKACASAEKQQPENATSAQRTEADCAKEPLGLLTAALEELRALMTDPTQYSVISAQVAVVSEKLNAVLGHRNDGGSLQRAKIQLSVLPSTLQKQDQAVVDLLLTAFCQNLMAASSFVPPERQSPWAVLFVRTLCGHVLLPAVLTRLRQLLRHQGQSLSTSHVLGLAALAVHLGECRSMLPEVDPDVLAPSAGSLCVPDFLNSLLTCRTRDSLLFCMNFCTAAVSYCLCKFSALRNCLSPGLIKKFQFVVLRLFPEARAPCAPEHAACVPWRPLYLPSADWQRAALSLWRRDSFQELLKDKEFYLTYRDWVQLELEIQPEADVLSDMERHDFHQWAIYERYLPAPTALGGCGGDLEEACTVLVSEIMDFHQSSRSYNHSEDSDLVLGGRTGNKDILSRLQEIALDLELDQGSAVPHGCSTPQSHFLFRVFRRRLQALARPDSMATSLRRQQELLTCKRLLLCLPPSVLVGGPQAGQPISPNCGEFFSLVNSELRNFCCHGSVLTSDITIHFFRGLLRVCLRSQDPALVANQTLTECQTKCPVILTSALLWWSSLEPVLCGRWMRCYQSPLPRELRRLQEAREFASNFASASASPAPSPAWIAAAALHFAWRGVRKEDVTAHLQRLDCQREELLIALFFFSLMGLLSSYLTQRDTAEHLKAVDICAEVLTCLERRKVSWLVLFQLTEKDAKLGHLLHLAPDQHTRLLPLAFYSLLSCFSEGAAVREAAFLHVAVDMYLKLLQLFVDGETRLQGHSESQGSPVQLITKARVFLLQLIPQCPKQCFSNMTELLAGRGDCDPEVSNALRQRQQADPSFDLYQEPQLF
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability (By similarity).
What are the official names of this protein?
Fanconi anemia group A protein homolog, Protein FACA.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein: RL25_PORGI
Sequence: MKTFQLTGTPRAEFGKKAAKAIRKEDQIPAVLYGGKGEGVNFIVSQDAVRNLIYSPEIFLVELTVEGSGSYKAILKEIQFHPVTDRIIHIDFLQVTDEKPVVMEVPVVLTGHAEGVKAGGKLSLEMRKLKVKALYSEIPEKLDIDVSDLQLGKTIQVGELHFEGLTLMNAKNAVVCAVKLTRAARGAAVKKQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: IN21B_ORYSI
Sequence: MAAAAAAPASSEKEVLPPSLTSSSEPPPLFDGTTRLYVAYHCPYAQRAWIARNYKGLQDKIKIVAIDLADRPAWYKEKVYPENKVPSLEHNNQVKGESLDLVKYIDTNFEGPALLPDDSEKQQFAEELLAYTDAFNKASYSSIVAKGDVCDEAVAALDKIEAALSKFNDGPFFLGQFSLVDIAYVPFIERFQIFFSGIKNYDITKGRPNLQKFIEEVNKIHAYTETKQDPQFLLEHTKKRLGIA
What are the official names of this protein?
Protein IN2-1 homolog B, Glutathione S-transferase GSTZ5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: FLOA_STAS1
Sequence: MIGLIIIVVIVLVALLLLFSFVPVGLWISAIAAGVKVGIGTLVGMRLRRVSPRKVISPLIKAHKAGLHLTTNQLESHYLAGGNVDRVVDANIAAQRADINLPFERGAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSEHHTQVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVAQEQEMKAKVQEMRSKVVEAEAEVPLAMAEALRSGNLGVKDYYNLKNVEADTGMRNSINQRTNQKDDESPDK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: LGT_RHOPA
Sequence: MPFFAVAFPVFDPVAVAIGPFAIRWYALAYIAGIVIGWLYARMLLQRQRLWGGPSPISLEAFDDFILWVTIGIILGGRTGYVLFYNLDFFIRHPAEIFELWKGGMSFHGGFMGCVAAVVLFGWKRKVPILSLGDITCAVGPIGLFLGRIANFINGELWGRPADASVPWAMVFPNAGPLPRHPSQLYEAGLEGIGLFVILALMIRAGALKRPGLIIGAFLTFYGLARITGEFFREPDPQLGFLWGDMTMGMLLSIPMVIVGILVMITTWRRGRGAPAAATPSSEAAS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAUB_PSEF5
Sequence: MALLQLERISAQYPGAAEPVLADISLTLGPQQLLVALGPSGSGKTSLLNLIAGFVEPSAGRIQLDGVPVQGPSAERGVVFQDDALLPWQDVLGNVAFGLELAGVARDKREARAREMLALVDLAGFDKRRIWQLSGGQKQRVGLARALAADPRVLLMDEPFGALDAFTREQMQELLLQVWRRTAKPVFLITHDIEEAVFLATDLILLAPNPGQIVERLNLDFGQRYAAGESARAIKSDPRFIETREHVLARVFSQRSATQQQERP
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YORK_BPSPB
Sequence: MEYRLIGDNDYNFDPLATILKNRGIEDPKLFVNVDQSSVIHYSKLNNIDKAADCLIRHLNNKNKLFVQVDSDVDGYTSSSIIINYIKKICPKANIHYRIQDGKEHGIFIDTIPDDVDLVIIPDAGSSQFEEHEALNKRGTEIIVIDHHECERVSEHAIVVNNQLSPNYSNKTLTGAGMAYKFCQAIDEKLNKNEAEQFLDLVSIGNIADSADSRNLETRYFMNEGLKKIKHPLLKKLFKKQEFSTKGDKSIQNTQFFINPLINAAIRVGSSEEKDQMMRAFLLSKEKVPYKKRGQSETELVSIHEDTVRILGNLKAKQKRIVDAAGVEIKNRIEEKSLTANKVLIVYIEGILDKSLTGLVANQLAEEYKKPVLLARNDPEKGKDILSGSIRGYDKGFIKDFKKELIDTGLFEFVEGHPNAAGFAIKRQNLILVNKVLNEKFKDINIEEDIQNVDFEIPAKRLRKEFILQLDGYKDYWGYKVEEPLIAITDLEIEVEQIEHLGKKNKTTVKFKHGDIEYIRFKSDENYFNQLTASNGTLVINVIGKAKANEYKGKKTPQIEIYELEVVRTKQKELVF
What is the function of this protein?
Putative single-stranded-DNA-specific exonuclease.
What are the official names of this protein?
Putative single-strand DNA-specific exonuclease yorK.
What is the protein family that this protein belongs to?
Belongs to the RecJ family.
Protein: RMXL2_MACFA
Sequence: MVEADRPGKLFIGGLNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPANAKAAARDMNGKSLDGKAIKVAQATKPAFESSRRGPPPPRSRGRPRFLRGTRGGGGGPRRSPSRGGPDDDGGYAGDFDLRPSRAPMPMKRGPPPPPRRAGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPPPPRRDPYLGPRDEGYSSRDGYSSRDYREPRGFAPSPREYTHREYGHSSVRDDCPLRGYGDRDGYGCRDRDYGDHPSRGSYREPFESYGDLRGGAPGRGTPPSYGGGGRYEEYRGCSPDAYSGGRDSYSSSYGRSDRYSRGRDRVGRPDRGLSLSMERGCPPQRDSYSRSGCRVPRGGGRLGGRMERGGGRSRY
What are the official names of this protein?
RNA-binding motif protein, X-linked-like-2, Testis-specific heterogeneous nuclear ribonucleoprotein G-T, hnRNP G-T.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH60_BURVI
Sequence: MAAKDVVFGDSARSKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKYVASGMNPMDLKRGIDKAVAAAVEELKKISKPCTTNKEIAQVGSISANSDSSIGDRIAEAMDKVGKEGVITVEDGKSLADELDVVEGMQFDRGYLSPYFINNPDKQVAVLDNPFVLLHDKKVSNIRDLLPVLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVGKENTTIIDGAGEAASIEARVKQVRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRARTAIAGLTGANADQNAGIKIVLRAMEEPLRQIVTNGGEEASVVVAAVAAGKGNYGYNAATGEYVDMVEAGVVDPTKVTRTALQNAASVAGLLLTTDAAVAELPKEDAPMPGGMPGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP255_MOUSE
Sequence: MDPVLVLVLTLSCLLLLSLWRQNSGRGKLPPGPTPFPIIGNILQIDIKNISKSFNYFSKVYGPVFTLYFGSKPTVVVHGYEAVKEALDDLGEEFSGRGSFQIFERINNDLGVIFSNGTKWKELRRFSIMTLRSFGMGKRSIEDRIQEEASCLVEELRKANGSLCDPTFILSCAPSNVICSVIFHNRFDYKDEKFLNLMERLNENFKILNSPWMQVYNALPTLINYLPGSHNKVIKNFTEIKSYILGRVKEHQETLDMDNPRDFIDCFLIKMEQEKHNPHSEFTIESLMATVTDIFVAGTETTNITLRYGLLLLLKHTEVTAKVQAEIDHVIGRHRSPCMQDRTRMPYTDAMVHEIQRYIDLIPNNVPHAATCNVRFRSYFIPKGTELVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSIGKRMCVGEALARTELFLILTTILQNFNLKSLVDTKDIDTTPVANTFGRVPPSYQLYFIPR
What is the function of this protein?
Metabolizes arachidonic acid mainly to 19-hydroxyeicosatetraenoic acid (HETE).
What are the official names of this protein?
Cytochrome P450 2C55, CYPIIC55.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: ATG15_DEBHA
Sequence: MKQLGEEHPLISTKRPRAKKRRSIAICAAVLTLIAFGFIRFVPKDILAGGWYEGEKDGLSALDNEEVRDMQTDGTTFELKHIFHRGTGSHNYMVHRRLDVTKEYLEAHSEELEELTTMQTSEVDESNLQDVYDAYDWPQAHTGKNPWTIKLQIRQSPTNGVVKRLKERHTPNFLDSYLAYALSVKGNPALLNKIELEWEDEHEIPIPDVKDRDTVVSLATISSNAYVKFPKDDKEKKRSDWIDVGDPWVPDENHTDINFGWADDGLRGHVFVSTDNKTVVIGIKGTSGAGLIGTGPEETTANDKLNDNLLFSCCCARVGYMWTTVCDCYQKAYTCDQDCLEKELMRQDRYYQATLDLYRNVSQLYDPSTTNIWVTGHSLGGALASLVGRTYGLPAVAFEAPGEMLATRRLHLPQPPGLPKHLENIWHFGNTADPIYMGVCNGVSSSCNVAGYAMETACHTAHQCVYDVVTDMGWRVNLLNHRIHTVIDDIILAYNDTPPCVQQPPCRDCFNWRFTSSDDNKNDEPPLPNPLHPKPPSTVRSSNMPHEQSPNASRSLSSLCTEPSCTSSFQSVSPSFSSQLPSHPSQNPQRCLRRTWYGRCSKWGHNSAAHHVSSI
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: CCMM_THEVB
Sequence: MAVQSYAAPPTPWSRDLAEPEIAPTAYVHSFSNLIGDVRIKDYVHIAPGTSIRADEGTPFHIGSRTNIQDGVVIHGLQQGRVIGDDGQEYSVWIGDNVSITHMALIHGPAYIGDGCFIGFRSTVFNARVGAGCVVMMHVLIQDVEIPPGKYVPSGMVITTQQQADRLPNVEESDIHFAQHVVGINEALLSGYQCAENIACIAPIRNELQRQEDPPTLHVEMLTGEKNTMTTDYGTHVRQLLQQGYQISLEYADARRYRTSSWQSGPTLTGQQESQVMAAIAQLLKEHEGEYVRLIGVDPKAKRRVFEEIIQRPGQAAVASSSSSRPSATVNASPVGSLDAAVVAQVRQLLQQGYQIGTEHADARRYRTSSWTSCAPIQSKQEPEVLAALEACLQEHAGEYVRLIGIDQKQKRRVLEQIIQRPQGPVAIAPKTPTPVATSHASVSSGGNDTLLSADLVNQIQDLLRQGCQVITEYADQRRFRTSSWQSGIKITSAQQINDLRSFLAEHQRDYIRLVGVNPQAKQRVLETIIHRPNGKAASNGNSTRGQGFTPRPTASSQGSPSTHSLSQEVIEQVRQLLQQGYTLGLEHVDARRYRTNSWQSGPRIEAKNLNEALAAIQACLQEYSGEYVRLIGINPAGKQRVAEILLQQAAK
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both forms of CcmM (Probable).  CcmN interacts with the N-terminus of full length CcmM, and then recruits the shell proteins (CcmK) via CcmN's encapsulation peptide.  Shell formation requires both CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton (By similarity).
What are the official names of this protein?
Carboxysome assembly protein CcmM, CcmM70, M70, Carbon dioxide concentrating mechanism protein CcmM, Carbonic anhydrase.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: PUR5_CROS5
Sequence: MDYQDAGVNIEAGRSFVDKIRRSVESTYNAQVLGGLGGFGGYFELPTGYENPVLVSGTDGVGTKLKIAQALNRHQTIGIDLVAMCVNDILTSGAKPLFFLDYLATGKLNPQQLSDVVTGIVEGCHLSDCALLGGETAEMPGFYGVGEYDVAGFCVGVVEKANLLDGSQINIGDVAIGLSSSGVHSNGFSLVRKIVEVNGLSWGDRFESLGNQTLGEVLLTPTQIYVKPILEALKSGIEIKGMAHITGGGLPENLPRCLNNNQSIKINSESWSILPIFQWIANMGNVATAAMFDTFNMGIGFVIIVPKNQGKTSIEWLKSQGISAYEIGEVIEGNRELVGL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_RICAH
Sequence: MATKKAGGSSRNGRDSAGRRLGVKKSDGQYVIPGNIIVRQRGTTIHPGTNVGLGKDHTIFALIEGRVEFLTKRNHKIVNVKEITNA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GATA_STRPQ
Sequence: MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFITVSEEAALKQAAAIDAKGIDSDNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTVKENAQLLNVVASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKETVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDAKNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFADYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVGLQLIGPKYTEETIYQAAAAFEAVTDYHKQQPIIFGGDK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: METK_ANADE
Sequence: MPLQDFLFTSESVTEGHPDKMADQISDAVLDAVLRQDPKGRVACETLLKTGYVMIAGEITTKARIDYPKLARETVRRIGYTSGDMGFDANTCAVLVAVDQQSPDIGQGVDTGGAGDQGMMFGYACDETPELMPAPIQYAHAVTKQLAKARRAGLDLLRPDGKSQVSVEYRDGRPARIDTVVVSTQHAESVSNKRLHEAVREQVIAKALPKRLVDRKTRILINPTGRFVIGGPMGDTGVTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVAAGLAARCEVQVAYAIGVAEPVSVMVDTFGTAKVPEGKIARAVREVFGLTPRAIIEGLDLLRPVYEKTAAYGHFGRTEKTFTWERTDKKDALADAAGLSKIRAVAGV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPC2_SHIFM
Sequence: MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFTDDKRDDGDKTYARLGFKGGTQINDQMIGFGHWEYDFKGYNDEANGSRGNKTRLAYAGLKISEFGSLDYGRNYGVGYDIGSWTDMLPEFGGDTWSQKDVFMTYRTTGLATYRNYDFFGLIEGLNFAAQYQGKNERTDNSHLYGADYTRANGDGFGISSTYVYDGFGIGAVYTKSDRTNAQERAAANPLNASGKNAELWATGIKYDANNIYFAANYDETLNMTTYGDGYISNKAQSFEVVAQYQFDFGLRPSLAYLKSKGRDLGRYADQDMIEYIDVGATYFFNKNMSTYVDYKINLIDESDFTRAVDIRTDNIVATGITYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane (Probable).  Plays a role in virulence (PubMed:8359885).
What are the official names of this protein?
Outer membrane porin C 2, Outer membrane protein C 2, Porin OmpC2.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: TDM1A_MOUSE
Sequence: MGDFIGHISPGLFLVFYGLYQAVIVSRAVIFNDSLLYPSYLSKNKGKWARLWKIAHAGWLKVVIGSLLIVYEISCVKEGLTLMTKGVPPRFMYPKEWQHLTMFFLLTLDGCVEMVSKNVLRQRCVLLERGATVLGVYVLLLLLVSHVKESSGVELQVHSLLILVVFLLMLVLTAELWAPEMFHLWMIETFLILIMGSWLIQAAFILFRPVSGFPWEDDDISDIMFVTTFFCWHVMINALCMLGIYGVSSFWHRCYSPSLRPMGSKEALYQESSSGTFYKLLQEAEQQDKDDQAPLLSKISPCDRA
What are the official names of this protein?
Transmembrane epididymal protein 1A, Transmembrane epididymal protein 1-1.
What is the protein family that this protein belongs to?
Belongs to the TMEM45 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS12_BIFA0
Sequence: MPTIEQLVRKGRRGKPKKSKTLALKGSPLRRGVCTRVYTTTPKKPNSALRKVARVRLSSGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGALDTQGVKDRKQGRSLYGAKKAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ECDH_ASPRU
Sequence: MEFPLYTTTLLCGVISSTLLLLLLNKLTTWEHIVPSKVPWIDRRSEPFGYLRAKCRSFFNMKENITEAYYAFNKEGRAAALAIAFGRPQIILPPKYIRWIIDQPESVLSIDPIHNEFHAFVRDGLVGDHLVQEVLRRELAGHLAHLTREMNEEIADSVESVLGVSKEWATVPLRDSMRIIIARISNRLFVGKELCRNEDYIRNAVGLGMAVMPQTLVQDLLPQLLKGPLSFATKLFTRITLAGLSGHLSPVVRQRIQDVQTAEKDQLPLELLTWMAQRALQRGESATSIEEKLIARIAMANLASIETTTNTITKCMEDMTALSNETGGYLELMRQEAHTVLEACNYSPIKADLEKLVHIENALKESLRLAVVFPGLIRQVTSRTGVTLDDGTHLPHGARISVAAYAIHRDDANWTDAARYDPSRHEKASLPMSRGSEQLLSFGLGKRACPGRFFVTDELKLLFAHILTKYEFKVIKPPVTKVGLLKELTMRGPQEQLVIRRVK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of echinocandin B, a fungal lipidated cyclic hexapeptide that acts as an antifungal agent (PubMed:22998630).  Linoleoyl-AMP, produced by the fatty-acyl-AMP ligase ecdI, is transferred to the initiation carrier domain (T0) of ecdA (PubMed:22998630).  The linoleoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-ornithine, L-threonine, L-proline, L-homotyrosine, L-threonine, and 4R-methyl-L-proline to form the linear hexapeptide (PubMed:22998630).  Thereafter, the terminal condensation (C7) performs macrocyclization of the NRPS product and the cyclic scaffold is released from ecdA (PubMed:22998630).  All six of the amino acid residues are hydroxylated, including 4R,5R-dihydroxy-L-ornithine, 4R-hydroxyl-L-proline, 3S,4S-dihydroxy-L-homotyrosine, and 3S-hydroxyl-4S-methyl-L-prolin (PubMed:22998630).  In the pathway, all the hydroxylation reactions are proposed to occur following completion of the cyclic peptide, so the unhydroxylated precursor produced by ecdA will undergo six rounds of hydroxylation (PubMed:22998630).  Five hydroxylase genes (ecdG, ecdH, ecdK, htyE and htyF) are embedded within the echinocandin B (ecd) and L-homotyrosine (hty) clusters (PubMed:22998630).
What are the official names of this protein?
Cytochrome P450 monooxygenase ecdH, Echinocandin B biosynthetic cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ERD23_HUMAN
Sequence: MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPMPI
What is the function of this protein?
Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.
What are the official names of this protein?
ER lumen protein-retaining receptor 3, KDEL endoplasmic reticulum protein retention receptor 3, KDEL receptor 3.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
Protein: MIAB_BURM1
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDSPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPDLLIGVGGCVASQEGASIVSRAPYVDLVFGPQTLHRLPQMIDARRTSGRAQVDITFPEIEKFDHLPPARVEGPTAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGALTAGSSEVADFATLIEYVADIPGIERIRYTTSHPKEFTQRLIDTYAKVPKLVNHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPDLSLSTDLIVGFPGETEEDFDKMMALVHDMRYDTSFSFIYSPRPGTPAANLHDDTPRDVKLKRLQLVQATIEENVARISQSMVGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPLAAHPRLIGQMIDVKINHAYPHSLRGELVLVSDDASAATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK5_RHDSA
Sequence: MSQSLKTYYKEKVVPLLMETFEYKNIHEVPKITKITINRGLGEASKNNKALESSVQELAIISGQQPVITKAKKSVAGFKIRDGMPVGIAVTLRSKMMYAFLERLIHLSLPRIRDFKGISVQLFDGRGNYNLGLKEQLIFPEIEYDRIDQIRGMDIAITTTAKTQQEGIALLKALGMPFNDN
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MED21_HUMAN
Sequence: MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFNNIQTAINKDQPANPTEEYAQLFAALIARTAKDIDVLIDSLPSEESTAALQAASLYKLEEENHEAATCLEDVVYRGDMLLEKIQSALADIAQSQLKTRSGTHSQSLPDS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21, RNA polymerase II holoenzyme component SRB7, RNAPII complex component SRB7, hSrb7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.