PharMolix/UniProtQA huggingface dataset:
Protein: SYE1_BRUA2
Sequence: MTVTVRFAPSPTGYIHIGNTRTALSNWLYASKNNGKFILRYDDTDVERSKDEYAQAIAVDLDWLGVRPDRVEYQSKRFDIYAKAVEKLKTAGLLYACYETADELERRRKFRLARRLPPVYGREALKLTDAEKAALEAEGRKPHWRFLLPNFESDPFATQRTEVHWDDLVRGPQTVDLASMSDPILVREDGTYLYTLPSVVDDIDMGVTHIIRGDDHVTNTGVQISIFKALGATPPVFGHHNLLTTISGEGLSKRTGALSVGSLREAGYEPMAVASLAILIGTSESVTAAPDMAALAEHFDLASISKSSAKFDPSELDALNRSLLHEMPFEKAKPRLEALGICGAKAESFWLAVRGNLDRFSDVSHWWQVVSGDLPEAPDLSGEDRDFVRHAFDLLPPEPWNGQTWKSWTEAVKSATGRKGKNLFMPLRLALTGQAHGPELADLLVLVGLERTKSRRP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_LACLA
Sequence: MIKEINIKIKNFEGPLDLLLHLVSQYEMDIFEVPLVPVIEQYLIYIQTMKELELEVAGEYMLMASQLMLIKSRRLLPTVTETFIEDTEQLEYDLLAQIDEYRKYKMLSQDLDELHQERSHFYSKAKTEIITDETVLLQDKSALDLFLAFTKILELQRQHFQDENTKIAAEKFTIADKILELSTRFTEQKICKFSDLFSSSTNKDELVTTFMALLELIKNQQISFSQGELFGEIILERKETSE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RN170_DANRE
Sequence: MEGSVCVDGAAAPAPDEASLIEGVSNAVLLVLVLSVTLLAGLTTLLCRSEQQRIHPESQERVRVVREQLQAEQVSSESRHQFYSDMSCPVCLQQAVLPVETNCGHLFCGSCIIAYWRYGTWLGAISCPICRQMVTLLFPLFQDSEQSAVAADSPVEPTLILTDISDYNRRFSGQPRSLLDRLRDVPTLLRHAFREMFSVGGLFWMFRVRILLCVCGALAYLVSPLDFLPEGVLGLLGFLDDFFVILLLFIYISIMYREVVTQRLAG
What is the function of this protein?
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway.  Also involved in ITPR turnover in resting cells.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF170, RING finger protein 170, RING-type E3 ubiquitin transferase RNF170.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMH_FLAPJ
Sequence: MLKETVDGLNIKPDGVYVDVTFGGGGHSKEILSRLGPEGKLFGFDQDEDAWENALPDERFTLIQENFRYIKRFLRFNGIKKVDGILADLGVSSHQFDVPERGFSTRFDAELDMRMSKKNDLTAFNIVNEYDETNLRRIFAEYGELGNALAIARAIIEAREKEKIVNTEDLKQVLARFLPNNKAHKILAQIYQSIRIEVNQEMDVLKEFLEQSLEVLDQGGRLSVISYHSLEDRLVKRFMKNGLFEGEPEKDFFGRFEVPFKLIGKMIIPSNQEIKINNRARSAKLRIAEKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_HALOH
Sequence: MKGYYNFADIEKKWQDKWEKDGLYKTQEETDKDNYYVLEMFPYPSGNLHMGHVRVYSIGDVIARFKRMNGYNVLHPMGWDAFGLPAENAAIKHGNIHPQDWTWDNIKNMKKQMKSLGLSYDWDREVTTAKEDYYKWTQWFFVKMFKKGLAYKKKAAVNWCPGCETVLANEQVVNNACERCGTEVEEKELEQWFFKITNYAERLLEDHKLLQNWPEKVKIMQRNWIGRSEGMRIKFPVKGSSEEIEVFTTRPDTIFGATYMVLAPEHPLVEKLISGTEKEKEVRQFIDRVKKQKEMERTSPESEKEGLFTGAYAINPMTGEEIPIMIANYVLMGYGTGAIMAVPAHDQRDFDFARKYDLPIRVVIQPEEREEELKDTDLNEAYEGSGHLINSDKYNGLTVKEAFDVMAEDMEKEGIGKREVNYRLRDWLISRQRYWGTPIPIVYCEKCGTVPVPEEELPVVLPRDVEFSPTGESPLAKVDEFVNTTCPVCGGKARRETDTMDTFVDSSWYFLRYTDPKNDKLPFSKENAKKWFPVDQYIGGIEHAILHLLYARFFTKVIYDMDMIDSVEPFTNWLAQGMVLKDGAKMSKSKGNVVDPEDILDRFGADTARLFILFAAPPEKDLEWSDRGVEGAERFLNRVWRLVADNIKEIKNTDQASLDVNSFNKNEKDLYRNLHVTIKRVTEDIGERLNFNTAISAIMELTNATYQYLNGVEKVNYTLIKDIIEKMLLILAPFAPHMTEELWSELGNDESIHIQKWPGYEEKALKKDEVTIVVQVNGKVRDKLQVSADIDEDKLKEQVLELPRIQKYTEGKEIVKTIIIPKKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMTC2_DROME
Sequence: MPSLEPWLWGDSCSWLGMLAMLRLRLHKSNMDFTCLFCCSLAFVLYLNTLGAGFVYDDRRAILANADVSGGTPWQRSFSNDFWGTPLTDSGSHGSWRPLCVLSFRLNYLIGGGFAPWGFHLVNNLLHCVATALVVRVARTLLASVWAVLAAGALFAAHPIHTEAVAGVVGRADLAACVCYLLTYLSYLRHMRWRESGDPRQWLALGATLILAAAGLLCKETAITALLVCALFDVMRGLSGQVDKQRLRSVCIVLGALFCMAYCRLVIVPGPQTAFSSADNPIARTPSAWTRLLTFLYLPVFNLRLLLQPNVLSFDWGMDALPRVTSLWDRRNAQSACFYSVLVGVAWGSCRQLLSGSKEVTHCGVSSTFPQYHIQKVASRKSRSKRKRLANNTKYQAFEAAYHQQQQEALPCRDCNNNNSSGYVYEGSSPVAQAPAQAPHLVSSAFRGSRSSSSCSNSTNSSSSSSSSSSSSSSSSSSLSGGFQCSSKDYALEGMSPANRHACVLIMSLSFLALPFLPASNLLFYVGFVVAERLLYLPSVGFCLLVGYGVSKLMSCNQRTRNILLLSFSLLLAAMSLRTLRRNADWRDEESLYRSAIAINPPKALGNLGSVLSSQGRYEEAKQVLQEAIRFRPNMADVHFNLGILHQNQQVYPAAVECFQRAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARSSAYLQLGALYVEQGKLQRALAIYREALSSLPGLPQQREILYQRIGDVLGRLQQWDEAERHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFLSLQSRHHESAIYHRRAAELAPNDYTLVVAAATAMRLLDRKVDAEMWYRKAVALRPGDAHAHTNLGAILHLLGRTNHAAASYKAALRLQPGDAITLGNLAKLGVTNV
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
What are the official names of this protein?
Protein O-mannosyl-transferase TMTC2, Transmembrane and TPR repeat-containing protein CG4341.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: E1134_IXORI
Sequence: MEVKTFAFLQIAVFIALGIQIFAAVTAAADANEEVFTVEYCGMNCTQKSDGTWTECSGKNKDCRCYHESDAREGLCLSTEYTDFSQFETPSNSDLEAATPRPRKTLYPVRNPHGPKTRGLGYDKRILRDRVKFLI
What is the function of this protein?
Salivary chemokine-binding protein which binds to host chemokine CXCL1.
What are the official names of this protein?
Evasin P1134.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_RAT
Sequence: MESGPCSRPAEPRHCVSGRAGAGLAFPAFPLSAAGAEPGSRIGTVAAVLPAGGCGERMGVRTPKQFCRVLERPLISYTLQAMERVCWIKDIVVTVTGENMEAMRSIIQRYGHKRISLAEAGATRHRSIFNGLKALAEDQPGCELTRPEVVIIHDAVRPFVEEDILLRVVLAAKEHGAAGAIRPLVSTVVSPSADGHLDHSLDRAKHRASEMPQAFHFDVIYEAYQKCSDFDLEFGTECLQLALKYCHRKAKLVEGTPDLWKVTYKQDLCAAEAMIKEKISQEICVVVNTKDEESVGHLLEEVLRNELNCIKVTSTVLDRTSGDIENFIDQCYSFICVNVVSSESRETRKLLSILEESSLPLLYPVVVVLVHCFDFTVVPLAQKMENLVWIRELAKEAKGRNVLLSGVLLNHSQDEQKLQESLVQSAAIIAALVKERNSALVGQLLVA
What is the function of this protein?
Cytidylyltransferase required for protein O-linked mannosylation (By similarity).  Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate.  CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).  Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively (By similarity).  Not involved in dolichol production (By similarity).
What are the official names of this protein?
D-ribitol-5-phosphate cytidylyltransferase, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein, Isoprenoid synthase domain-containing protein, Notch1-induced protein.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TRPB_BACAN
Sequence: MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: CU16D_LIMPO
Sequence: EIFPFNVPEGKNDPAFLQNLQQEALNYINQQQVPNLEKHKAEELKVAAKERAAYNAGYY
What are the official names of this protein?
Cuticle protein 16 isoform D, LpCP16d.
Protein: ILK_HUMAN
Sequence: MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARINVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLVANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
What is the function of this protein?
Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715).  May act as a mediator of inside-out integrin signaling (PubMed:10712922).  Focal adhesion protein part of the complex ILK-PINCH (PubMed:10712922).  This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway (PubMed:10712922).  Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells (PubMed:10712922).  Regulates cell motility by forming a complex with PARVB (PubMed:32528174).  Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).
What are the official names of this protein?
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, Beta-integrin-linked kinase, ILK-1, ILK-2, p59ILK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: PRMC_SYNY3
Sequence: MNKGFVSGEEFARWYATARQMAIAHGIETGELNWLLQGWTDLDRLTLRLQDFAHREIALQETWENIQRGWRRRVEEKYPVQYLLGQTQWRDFVIKVTDDVLIPRPETELIIDIVQHEHSALSPSNCADHWVDLGTGSGAIALGLAATFPQALVHAVDCSGSALAIARENAQLNQFGDRIQFHQGYWWEPLEHLKGQVQGMVSNPPYIPQRELAQLQPEVIKHEPLLALDGGPDGLQAVEQLIRRSPTYLKPGGFWLVEIMTGQAPMVAELLRASGAYQDIQIHRDLASIERFVSARTLS
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, M.Ssp6803HemKP, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: PRMA_SHEWM
Sequence: MPWIQLKIDTDNQHADTLSDLLMEEGSLSITLEDGKDTPIFEPTLGETPLWNHTVLTALFEADRDLSIVVDNLKLQPFLGADFSYKIEQVEDKDWEREWMDNFHPIKFGERLWICPSWREIPDPEAVNIILDPGLAFGTGTHPTTALCLEWLDSLNFDNKEVIDFGCGSGILAVAALKLGATKVTGIDIDYQAIDASKANAERNGVEDQLTLYLPEDQPENLKADILVANILAGPLRELAPLIAEKVKPGGQLALSGLLQEQALEVAEFYTQWFDMDEPAHKEEWSRLTGIRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIE_STRR6
Sequence: MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQYSGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Oligopeptide transport ATP-binding protein AmiE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYH_ACHLI
Sequence: MNYIKVKGTYDVLPTEAENWVALESYVRKLFKTYNYGEIRTPMMEYSNVIHRETELSDMVIKETYNFKDKSDRDLTLRPEGTAGVIRSYVENKLYAQAGVTKLYYMGPNFRYERPQKGRFRQFMQFGCEVLGSNEPSIDAEVIELAYETIYRLGLKQVSVKLNSLGDDASKANYRQALIDFLTPVKDKLSKDSQDRLTHNPLRILDSKDTADIELIKNAPLPLDYLNETSKQHFDSVLELLNLMNIPYEIDRKLVRGLDYYAHTVFEIHATIKGFGAQNALGGGGRYQNLVKELGGPDTPGIGYAFGMERLLSALEQEGITLTSPKQLDVYFITFDQQSRKKAIQLQHILRSENILSDIDHLNRGFKPQLKEALRYDSKFIIIIGENELNNNVVQLKNTKTEEQVEVSMDTLLDTLKELL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_SYNPW
Sequence: MAGGVTGGGSATWSDRFEQGLHPAIERFNASIGFDITLLQEDLDGSMAHARMLAQCGVISEAEADQLCGGLEQIRAEAAEGRFQPGLDDEDVHFAVERRLIALLGPVGKKLHTGRSRNDQVGTDLRLWLRRRIDELIPQVKTFQRALLRQALSHRRTLIPGYTHLQRAQPVCLAHHLLAYVEMLERDRQRLEDVRKRVNVSPLGAAALAGTPVPIDRRSTAAALGFDGLYANSLDAVSDRDFAVEFSAAISLVMVHLSRLGEEVIFWASEECGFVRLSDRCATGSSLMPQKKNPDVPELVRGKCGRVFGHLQGLLTMIKGLPLAYNKDFQEDKEALFDVVSTGSQCLEAMTILMDEGLSFREDRLEAAVAADFSNATDVADYLVARQVPFREAYQIVGSVVKQCLSEGVLLRDLSLERWQSFHPAIESDLYDALAPRQVVAARTSEGGTGFDRVEEQLSAWSERLDLANG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCAP_DROME
Sequence: MRTSMRISLRLLALLACAICSQASLERENNEGTNMANHKLSGVIQWKYEKRPFCNAFTGCGRKRTYPSYPPFSLFKRNEVEEKPYNNEYLSEGLSDLIDINAEPAVENVQKQIMSQAKIFEAIKEASKEIFRQKNKQKMLQNEKEMQQLEERESK
What is the function of this protein?
Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude.  The effect of CCAP is both ino- and chronotropic (By similarity).
What are the official names of this protein?
Cardioactive peptide, Cardioacceleratory peptide 2a, Crustacean cardioactive peptide, CCAP.
What are the subcellular locations of this protein?
Secreted.
Protein: CSSB1_ECOLX
Sequence: MLKKIIPAIVLIAGTSGVVNAGNWQYKSLDVNVNIEQNFIPDIDSAVRIIPVNYDSDPKLNSQLYTVEMTIPAGVSAVKIVPTDSLTSSGQQIGKLVNVNNPDQNMNYYIRKDSGAGKFMAGQKGSFSVKENTSYTFSAIYTGGEYPNSGYSSGTYAGHLTVSFYSN
What are the official names of this protein?
CS6 fimbrial subunit B.
What are the subcellular locations of this protein?
Fimbrium.
Protein: SNU71_KLULA
Sequence: MDTVLFVSPTLYCCGDTKNWQSQVPKPGYVPILKSDIPKFEQSLKQANSHRDHDKGNSVASKTNETDNSDEFKTSTSRYVDLKSFLPISLEQQLHTVCLAHFPLGLGSKGIDKVMDRLDNLIRKKLQVEDNETKFIKQWSYVDCVNTLTVYISFQESIVEEYGKAIQLLEKLFDNGSDGIGLHMDENTRRFVCDLTEGSPAKELDETAKDEFSALITMLRSEPGSISQEKGLAGNSAVEYNVDISTLSDLPSSSLDQLCKDIVEFRTRVITLEKEKRNKELAEEEKRRKQNLKHIFDRIKVTNGGSEKGSAPEAESDSEDSDDEVEGYDDEDADDYEAEKKRVQAERDAQEAQYESMVHSFQDSLLVQYSSLRQEYQRLQNYETHLQKNKGPMLKELLHLAMDPYHDHHRPYKESESKADEEDRKRESEEVPKKKATETEPETELELELEPETETETKLVSDADATTAAPKIKLALKKSIGKTKNEIEEEETPETDAFQQKLNLLRESGVVEELVKEYLGVYEPDLVSYIFENIEEHQSKQALETELTETFDEDSPVLVSRIWEAMEQ
What is the function of this protein?
Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA.  Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway (By similarity).
What are the official names of this protein?
U1 small nuclear ribonucleoprotein component SNU71.
What is the protein family that this protein belongs to?
Belongs to the SNU71 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRUA_METTP
Sequence: MKIALKIAYLGDRYYGFQRQPGLRTVESVMRDALLRIGVANGDFCYAGRTDRGVSALGQVIDFWIEEDRAYLAFPRVINSLLPSDVWAWARAVAPVGFSARWSALWREYRYFLFSPDIDLSAVREAAGHLVGTHDFRNFSMSKVDTVRRIISIDVNAHCGIVVFDVRAEGFIWNMVRRIVGALELIGIGEKPVDWILELLDPSTPHGAPTAPPEGLMLMDVGYSDLEWEEDRYTKQRVSRMLISEARRRAAMSGVIQEMLRRMRDTF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ATPA_SALPB
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MK14_XENLA
Sequence: MSSNQSYVFYRQELNKTLWEVPDRYQNLTPVGSGAYGSVCSSFDTRTALRIAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFSPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNYIQSLPYMPKMNFEDVFLGANPQAVDLLEKMLVLDTDKRITAAEALAHSYFAQYHDPDDEPIAEPYDQSFESRELDIEEWKRLTYEEVTCFVPPPLDSEEMES
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  mapk14a is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors.  Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.  Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets.  MPK2 is activated by upstream MAPKK/MAPKKK and stimulates MAPKAP kinase 2 to phosphorylate small heat shock proteins.  Does not phosphorylate myelin basic protein or MAPKAP kinase 1.
What are the official names of this protein?
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Mitogen-activated protein kinase 2, MAP kinase 2, MPK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: KAD2_SCHPO
Sequence: MAGMRLILVGPPGAGKGTQAPNIQKKYGIAHLATGDMLRSQVARQTELGKEAKKIMDQGGLVSDDIVTGMIKDEILNNPECKNGFILDGFPRTVVQAEKLTALLDELKLDLNTVLELQVDDELLVRRITGRLVHPGSGRSYHLEFNPPKVPMKDDVTGEPLIQRSDDNADALRKRLVTYHEQTTPVVEFYKKKGKWAAVDAAQKPEQVWEQIVAILEKAE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Nucleus.
Protein: KEFG_ECO45
Sequence: MMSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAQELASHARAYGDWLANPLSPGGC
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YUBL_YERPE
Sequence: MSEALAVLPDDTFTREQAEVVAAQYTNVAIEDDQGAHFRLVVRQNGEMVWRTWNFEPGGTYWLNRYIADYGIRKPQ
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: Y859_CUPTR
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEITVAAKLGGGDPDSNPRLRLSMDKAMDANMPKDNIQRAIQRGVGGLEGVNYEEIRYEGYGLSGAAIIVDCLTDNRTRTVAEVRHAFSKHGGNMGTEGSVAFMFTHCGQFLFAPGTPEDKLMDAALEAGADDVVTNDDGSIEVTCPPNDFSAVKAALEGAGFKAEVADVVMKPQNEVSFSGDDAAKMQKLLDALENLDDVQEVFTNAVIED
What are the official names of this protein?
Probable transcriptional regulatory protein RALTA_A0859.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SHESA
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVHISDDQVSVQLDQNDDNLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NAC_METAC
Sequence: MGGRGMNPAKMKQMMKQMGIDVKELKDVKEVIIKTADSNIVIENANVTIMTVQGSETYQIVGDAKEVPKSLEIPADDIKLVMEQTGVSEEEARNALKNSNGDLAEAIVALSSA
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.