PharMolix/UniProtQA huggingface dataset:
Protein: AROC_CELJU
Sequence: MSGNTYGKLFTVTTFGESHGAALGCIVDGCPPGLELSEQDIQIDLDRRKPGQSRYTTQRREDDQVKILSGVFEGKTTGTPIGMLIENTDQRSKDYSNIKDQFRPAHADYTYMQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLKDFHGIEVRGYLSQLGPVKIETVDWDQVDQNPFFCPDASKVPAMEEFMKTLNKEGDSIGAKITVVATGVPPGLGEPIFDRLDAEIAHALMSINAVKGVEIGEGFAVVEQRGSKHRDEITPEGFLSNNAGGILGGISSGQDIIANIALKPTSSLHIPGRSVDVHGNPVEVVTKGRHDPCVGIRATPIAEAMLALVLMDHLLRHRGQNGGVQHRIPVIPASAK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NC301_HUMAN
Sequence: MPSSHIVLKEETRMLGLMYAIWMNLNSFGLAIIGILLIACEIILFLTKDETIQWPHVPSNRGSKANLILKELQLLVRSTWWFHRETAQRTCLYLA
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00301.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HFA1_YEAS7
Sequence: KGKTITHGQSWGARRIHSHFYITIFTITCIRIGQYKLALYLDPYRFYNITGSQIVRLKGQRPEYRKRIFAHSYRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVESAQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSGDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHENSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVSFPAKELHKLMKRYLEENTNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKEILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAPDLLMSWQFSSLRNYLVNPDGESDEFTKLSKPPSTSGKSSANSFGLLVNMRALESLEKTLDEVYEQIHIPEERLSSGENSLIVNILSPIRYRSENDLIKTLKIKLHENERGLSKLKVNRITFAFIAANAPTVKFYSFDGTTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTPLDKRFFVRKIINSSMYNDQKTTEENLKAEINAQVVYMLEHLGAVDTSNSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIGKNGNLILEPCSEQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLNDSFFSWVELIEQNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDYGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTAGNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNNFQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLEKQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRKELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDVNDDRAVVEFIERNSKKIDKNIEEFEISLLIDELKKKFEDRRGNIVLEELTRLVDSKRKR
What is the function of this protein?
Catalyzes the rate-limiting reaction in the mitochondrial fatty acid synthesis (FAS) type II pathway.  Responsible for the production of the mitochondrial malonyl-CoA, used for the biosynthesis of the cofactor lipoic acid.  This protein carries three functions: biotin carboxyl carrier protein, biotin carboxylase, and carboxyltransferase (By similarity).
What are the official names of this protein?
Acetyl-CoA carboxylase, mitochondrial, ACC.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IF2_BEII9
Sequence: MSESKNSGENTLSVTPTKTLSLKRPVEAGTVRQSFPHGRSKAVVVEKVKRRPIGPGGDGHPAREAAPTPAPAATVTAPPPAQRPAAPNPTAAPTTPPAAAVPNVPPPAPRAEVAPPSAQPAPAAPTAATPPAQPKAEPVPAPIAAQAAPAPVPPVPAPSAPVPSTSAAPAAPKPAPAPVSQAKPIQTAPVQTAPAAQASASQTTGPRPVAAGPRPATGAAKQATATPQRGAASPAQRPQTGGGQRSGGQQRNQSGGRGGPGRGESGSSRTPTGVVLRSLTDEEREARARALSGARIREEEDRKRAAAEAKAREEREAREREERAAAEARKAEEDARRLQEQEAKRRSEQEAKRRLSGGEPAPAASPSVARKPVMTATAAAPAAAAPSGRAAVTDEEETKRVIRRPGMPTKVIVPPRPTKGAEPKSRGRLTVATATGGEEEERTRSVAAFRRRQQRLRGHVNEVKEKLSREVILPETITIQELANRMSERGVDVIKLLMKQGQMAKITDVIDADTAQLIAEELGHTVKRVAESDVEEGLFDTVDVEEHLVPRPPVVTIMGHVDHGKTSLLDAIRHANVVSGEAGGITQHIGAYQITAPNGSPITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTAEAVAHARAAGVPIIVAINKIDKPDAKPERIRSELLQYEVQVESLGGDTLEVEVSATKKINLDKLLDLIALQAELLDLKANPDRAAEGTVIEASLDKGRGPVATVLVQRGTLRVGDIIVGGTHWGHVRALIDDKGATRSEAGPSMPVEVLGFSGSPEAGDRVAVVETEARAREITEYRERQRREQAAARGGQARGSLADMMSQLKNAGRKEFPLVIKGDVQGSVEAVVATLEKLNTDEVAARIIHAGVGGITESDITLAQAAGAVVLGFNVRALKEARALAEQQGIEIRYYNIIYNLVDDVKAAMSGLLAPTLREEMLGNAEILEVFNISKVGKVAGCRVTDGRVERGAHVRLIRDNVVVHEGKLSTLKRFKDEVKEVVAGQECGMAFESYQDMRPHDVIECYNVHEIKRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNGF_MYCTU
Sequence: MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADDGGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGALAGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEADVSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAADLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGFSVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHFADVARPGTPLHDPGKLAAVLDGVCARDVGASEPPVAATQEIPIDGGRPRGDDAWR
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMM1_TABYA
Sequence: MLLKSYVFFLLSLLIVGLFTSRDADAQYEDLVTGYLRKGGVSGVSDFEPIEVFGEDYDSDEADEDGKG
What is the function of this protein?
Horsefly salivary gland immunosuppressant protein that likely inhibits the host inflammatory response by regulation of anti- and pro-inflammatory cytokines (PubMed:18087067).  When tested on mouse splenocytes in the presence of LPS, it increases the secretion of the proinflammatory cytokine interleukin-10 (IL10) and decreases the secretion of the proinflammatory cytokine interferon-gamma (IFNG) in a dose-dependent manner (PubMed:18087067).
What are the official names of this protein?
Tabimmunregulin 1.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_VIBC3
Sequence: MNRYQALFQRLSAAQQGAFVPFVTIGDPNPEQSLAIMQTLIDAGADALELGMPFSDPLADGPTIQGANLRALAAKTTPDICFELIAQIRARNPETPIGLLMYANLVYARGIDDFYQRCQKAGVDSVLIADVPTNESQPFVAAAEKFGIQPIFIAPPTASDETLRAVAQLGKGYTYLLSRAGVTGAETKANMPVHALLERLQQFDAPPALLGFGISEPAQVKQAIEAGAAGAISGSAVVKIIETHLDNPAKQLTELANFTQAMKKATKI
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MRAY_PSYWF
Sequence: MLYWLFDSWLSQFYSPFSAVSSVTLRTLLTVITSLAFSIILGPRTIAYLRSVKYDQAVRDDGPKTHLAKTGTPTMGGVLILTSIGFSTLCWANLANPYVWILMVVMVIFGAVGWADDWLKIKYKNPKGLIARKKYFWLSVGALFVGSSLYYIASQQPDPAQTKAMVDLLIPLFKNWIVPLSALPLGLGFIIFTYFVINGSSNAVNLTDGLDGLAILPVVFVAAGLGVFSYVSGDVRFADYLHVPYIAYNSEVTIVCAAMIGSGLGFLWYNAHPAQVFMGDVGALALGAMLGTIAVMTRQEIAFAIMGGLFVAEALSVILQVGSFKLRKKRVLLMAPLHHHFEELGWKETQVVVRFWIIAILLVVLGLMTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDI_MYCBT
Sequence: MDIAGRSLVYFSSVSENTHRFVQKLGIPATRIPLHGRIEVDEPYVLILPTYGGGRANPGLDAGGYVPKQVIAFLNNDHNRAQLRGVIAAGNTNFGAEFCYAGDVVSRKCSVPYLYRFELMGTEDDVAAVRTGLAEFWKEQTCHQPSLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: MYO16_MOUSE
Sequence: MEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKVFQKQEGPLKRSKPGKRQKVRFGLADMIQDAVIHHHDKEVLQLLKEGADPHTLVSSGGSLLHLCARYDNVFIAEVLIDRGVNVNHQDEDFWTPMHIACACDNPDIVLLLILAGANVFLQDVNGNIPLDYAVEGTESSAILLAYLDEKGVDLSSLRQIKLQRPLSMLTDVRHFLSSGGDVNEKNDDGVTLLHMACASGYKEVVLLLLEHGGDLNGTDDRYWTPLHLAAKYGQTTLVKLLLAHQANPHLVNCNGEKPSDIAASESIEEMLLKAEIAWEEKMKESPSAPSLAQEELYEILHDLPDLSSKLSPLVLPIAKQDSLLEKDIMFKDTTKGLCKQESQDGPPETSMTSNCGKPEQVQVMPPAPSDDLATLSELNDSSLLYEIQKRFGNDQIHTFIGDIFLLVNPFKELPIYSTMVSQMYLSPTGQRSPSLPPHLFSCAERAFHRLFQERKPQNIILSGERGSGKTQASKQIMKYLTSRASSSCTMFDSRLRHAIYIVEAFGHAKTTLNNVSSCLIQYWELQCCQRRKHITGARISTYMLEKSRVVAQPPGQGTFLIFSWLMDGLSSEEKCGLHLNNFCAHRYVSQGMREDVSTAEHSLNKERLAALKHALNVIGFSTLEVENLFVILSAILHIGDIQFTALTEADSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDVIIRRHTIQMAAFYRDLLAKSLYSRLFGFLINTVNCCLQNQDEYKSLQTLDIGILDIFGFEEFQKNEFEQLCVNLTNEKMHHYIQEVLFLQEQTECVQEGVAMETACSPGNQAGVLDFFFQKPSGFFSLLDEESQVIWSGEPNLPRKLQGLLESSNTNAVYSPVKDGNGNVAFKGQGAAFTVMHYAGRVMYEMGGAVERNKDSLSQNLLFVMKTSENVVISHLFQSKLSQTGSLISSYPSFKFGGHKSTLLSKRTASSMVGVNKNYLELSKLLKKKGTSTFLQRLERGEPATAASQLTKSLADITAKLQRGSPHFILCIKPNTSQLPGVFDHFYVSAQLQYLGVLGLVRLFRSGYPVRPSFEDFLSRYEPLASVLLGETKGQAAEERCRLVLQRCKLQGWQIGVHKVFLKYWHVDQLSDLWLQLQRKIVTCQKVIRGFLARQHLLQRMSIKQQEVTSIKSFLQSTEDMALKTYDALVIQNASDIAREHDRLRKEVHTAYHRNRQEEGTKRAEDQGGCRHVHSNSVPVPMVVDSLAQALTGPSTRPPSLHSVFSMDDSTGLPSPRKQPPPKPKRDPNTRLSASYEAVSACLSAAKDAAGEALTRPRPHSDDYSTMKKIPPRKPKRSPHTKLSGSYEEIWGPPRPSGTMGQGGRHQAPGTLSVQWARPDSVPQCTPQLPLHLPLPQGDYDDDAEPVYIEMVGNAARAGGSETDSPDQGESVYEEMKYILPEEGCGLGMLTFLPASPPLFLETRKAIILEAAEGNCQPSKDTCDIPPPFPNLLPHRPPLLVFPPTPVTRSPASDESPLTPLEVKKLPVLETNLKYPVQSEGSSPLSPQYSKAQKGDNDQLASPGFPVFNGPSRISPPATPPPPPGPPPAPCGPPPAPCGPPPAPCGPPPAPCGPPPAPCGPPPAPCGAASASCGVAPAPCRPPTHFAFPPESVLVTAAKALTNSDLPRTQPKPSSAPVPGPCSSFVKAPYSPGKTARADLRKTSSTFSPPSPYSPPNSRPLSSPLDELASLFNSGRSVLRRSAVGRRIREAEGFETNMNLSSRDEPSSSEMASETQDRNANNHGTQLSSSLSSDVTAENGNPVTNGLAEDDGCSRLCLSGMGTSSFQRNRESHTTQVIHQLRLSENESVALQELLDWRRKLCEAREGWQEALQHPEPRAPPPPPCKKPTLLKKPEGGSCTRLPSQLWDSSM
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.  May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development (By similarity).  Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.
What are the official names of this protein?
Unconventional myosin-XVI, Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3, Unconventional myosin-16.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NYAP family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in puncta in soma and processes of astrocytes and dissociated cerebellar cells with the morphology of migrating granule cells.
Protein: RR31_SPIOL
Sequence: MASLLLGTPSMACHSVSFSFSHSQSVAGVSLSSPPTLSLSSSVSTSPALPLIYCGRGDRKTAKGKRFNHSFGNARPKNKNKGRGPPKAPIFPKGDPSQKED
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
30S ribosomal protein S31, chloroplastic, Chloroplastic small ribosomal subunit protein bTHXc, Plastid-specific 30S ribosomal protein 4, PSRP-4.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bTHX family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACDP_MYCLE
Sequence: MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
What are the official names of this protein?
Probable acyl-CoA dehydrogenase fadE25.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: KAIB_TRIEI
Sequence: MSPLKKTYVLKLYVAGNTPNSVRALKTLKEILEQEFQGVYALKVIDVLKNPQLAEEDKILATPTLSKILPPPVRKIIGDLSDREKVLIGLDLLYEELNEDEYNL
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: ACPS_STAAS
Sequence: MIHGIGVDLIEIDRIKVLYSKQPKLVERILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKIDYEGFIVHVSISHTEHYAMSQVVLEKSAF
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUT4_RAT
Sequence: MAPAGRKLQHESRCRPSRPVDAWRAAATTRGRCMGTPGARRTARRGGWGLPRTSSGLAAAGLLCTALTACLCWGQLPPLPWASPAPQRPVSVLLWWEPFGGRGGHSKPPPDCSLRFNISGCRLLTDRAAYGEAQAVLFHHRDLVKGPPDWPPPWGAQERTDEALELRVFDDQEGAVMLAREALETTGSRPPGQRWVWMNFESPSHTPGLRGLAKDLFNWTLSYRTDSDIFVPYGFLYPRSHPAEQPSGLGPPLARKRGLVAWVVSHWNERQARVRYYHQLRRHVSVDVFGRAGPGQPVPAVGLLHTVARYKFYLAFENSQHVDYNTEKLWRNAFLAGAVPVLLGPDRANYEGFVPRGSFIHVDDFPSAASLAAYLLFLDRNVAVYRRYFHWRRSYAVHITSFWDEPWCQTCRAVQTSGDQPKSIHNLADWFQR
What is the function of this protein?
Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins.  Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity.  Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins.  Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis (By similarity).  In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (By similarity).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 4, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: OTC_BORBR
Sequence: MTPPTTQNGPLRHFLQFKDFSPAEIAYVLERTRIIKDKFKRYEPHMPLHDRTLAMVFEKASTRTRVSFEAGMYQMGGSVINLTSNDSQLGRSEPIEDTARVISRMVDIVMIRTFEQTRIERFASHSRVPVINGLTNEYHPCQILADIFTYIEHRGPIAGKTVAWIGDANNMSYTWLQAAEMLGFTLHVSTPAGYELDPARIGAPAAGVLKQFKDPMQACQGAHLVTTDVWTSMGYEAENEERRAAFADWCVDAEMMAAADPQAVFMHCLPAHRGEEVTGEVIDGAQSVVWDEAENRLHVQKALMEFLLLGQLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_FINM2
Sequence: MSEVRVRFAPSPTGFLHIGGLRTALYNYLYAKRNNGKFLLRIEDTDRTRYVEGAIENLLEQLKWAGLDPDEGVVLDDEGNVTEVGECGPYIQSDRVKQGLYQKYIDELIEKGYAYYCFCSKERLDQVKAQQKADGLMPKYDGLCRGISIEDAKKRIANGEEYVIRLKLPENKEITFNDAIKGKITFNTNDMDDQVLIKSDGFPTYHFAVVVDDHLMGITHIVRGDEWISSTAKHVYLYQCFGWDVPEFVHLPVVLNKSGKKLSKRNDDVAVKDFRKKGYLPEAIDNYLALVGWSSEDNQEIMSMEELKHKFDFNRVSKSGGVFDTEKLNWINRHYIKEIENEKLASMLKPYLVEDGVISEDYPEYKLIEIASLFKEELDYMAEITEKVEFLFKDYEMDDDAKEFLNYEKLDELMNALKEEIESVDEIEKEFASGVMKKVQKKTGIKGKDLWMTTRAVVTGNVHGPDLDSIMVVLGKQEVLDRINKALNR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_CHAGL
Sequence: MINNTNSNISIKAVGKKIRISPHKMRKVIDQIRGRSYEQALMILEFMPYKACNYVLKLLSSVAANANHNFGLNKSDLFIEKIIADGGPKLKRFQPRAQGRGYPILKPTCNLMIVVKVKS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MAC2_CRANI
Sequence: ASMFKHDHYMDNGVRYPNGDGICEQLNETKCDAGFSYDRSICEGPHYWHTISKCFIACGIGQRQSPINIVSYDAKFRQRLPKLKFKPHMEKLKTEVTNHQNRAPEFEPEDGENLYVKLNNLVDGHYKFHNLHVHNGRTRRKGSEHSVNGRFTPMEAHLVFHHDEQTHFEPTRTKLGGAFPGHNDFVVVGVFLEVGDDGFGDEPDDEECKHILKGHHPDNNENGNGDNGNNGYNGDNGNNGDNGNNGYNGDNGNNGVNGNNGYNGDNGNNGDNGNNGENGNNGENGNNGENGHKHGCRVKKAKHLSRILECAYRNDKVREFKKVGEEEGLDVHLTPEMPLPPLKYRHYYTYEGSLTTPPCTESVLWVVQKCHVQVSRRVLHALRNVEGYKDGTTLRKYGTRRPTQKNKVTVYKSFK
What is the function of this protein?
Acts as a negative regulator for calcification in the shells of mollusks.  May function both as a calcium concentrator and as a carbonic anhydrase required for production of carbonate ions, which are assembled to CaCO(3) at mineralization sites.  Is important for shell formation in both the calcitic prismatic layer and the aragonitic nacreous layer (By similarity).  Shows inhibitory activity of crystal formation when present in free state but, when attached to the insoluble matrix, may regulate the form and size of aragonite crystal.
What are the official names of this protein?
Nacrein-like protein C2.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TI141_ARATH
Sequence: MATPFIAGVAVAATALAGRYGIQAWQAFKARPPRPKIKKFYEGGFQPTMTKREAALILGVRESVAAEKVKEAHRKVMVANHPDAGGSHFLASKINEAKDVMLGKTKNSGSAF
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM14-1, Chaperone DnaJ-domain containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NCAP_I77A3
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWMRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGQLSTRGVQIASNENMETMDSSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.