PharMolix/UniProtQA huggingface dataset:
Protein: ANGP2_CANLF
Sequence: MWQIVFFTLSCDLVRAAAYNNFRRSMDSIGRRQYQVQHGSCSYTFLLPETDNCRSPGSYVPNAVQRDAPLDYDDSVQRLQVLENIMENNTQWLIKLENYIQDNMKKEMVEMQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLDMEDKHIVQLRSIKEEKDQLQVLVSKQNSIIEELEKQLVTATVNNSVLQKQQHDLMETVHSLLTMISPSKSPKDTFVAKEEQIIYRDCAEVFKSGLTTNGIYTLTFPNSTEEIKAYCDMETSGGGWTVIQRREDGSVDFQRTWKEYKVGFGNPSGEHWLGNEFVFQVTNQQPYVLKIHLKDWEGNEAYSLYEHFYLSGEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDADNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKGTTMMIRPADF
What is the function of this protein?
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling.  Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.  In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.  In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.  Involved in the regulation of lymphangiogenesis.
What are the official names of this protein?
Angiopoietin-2, ANG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: ZGPAT_DROSE
Sequence: MEEYEAQLLVVEQALENAADDAQRQELLALKNNLQELLALTRDTGDEAPTDELPQQGNDLDDELQRLKSELSDLEAAGSSQTALDEERQLADLRTKYTAMVGEKCSAPHEHSWGTCYHNALICGVDDEVVINSEGVLDARLRVLFTNPTHREMLPCSYYLEGECRFDEAKCRFSHGALVTGSSIRKYNPPDFHKLSRSRPVFALLPDRLWHRGRVLCVNFVEQVCRVRLDGQDHKERERDFKFEELYPLTTDQDEDDELSSEESTSSMRDASSDEAESDMDDLEEARRARMVELSLFTYKPTDRLGAWEEFTRGIGSKLMEKMGYIHGTGLGSEGRGIVTPVSAQILPQGRSLDACMELREAANGDKDYFSVERKLKRAQRRQRKADEKAYVRESQRVDVFTFLNDRVLGPGESTQQSEQVAKKAKNNELQQHSTKTLNVETVRIADEIRRKQRDMAKVKQSLERNSGDAQLQKRLQVQMQSHKQELATLQAQERSLSKEQQTRKSKNKMFEF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBA_HUPLU
Sequence: MTATLERRESASLWGRFCDWVTSTENRLYIGWFGVLMIPTLLTATAVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAAAAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASVEAPSVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: 3MGH_MYCTA
Sequence: MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: PANB_BURP1
Sequence: MTYLQESSRPAVTVPKLQAMREAGEKIAMLTSYDASFAALLDRANVDVQLIGDSLGNVLQGQATTLPVTLDDIAYHTACVARAQPRGLVVADLPFGTYGTPADAFASAVKLMRAGAQMVKLEGGEWLAETVRFLVERAVPVCAHVGLTPQSVHAFGGFKVQGKTEAGAAQLLRDARAVEEAGAQLIVLEAVPTLVAAEVTRELSIPTIGIGAGAECSGQVLVLHDMLGVFPGKRPRFVKDFMQGQPSIFAAVEAYVRAVKDGSFPGPEHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_DESRM
Sequence: MQGTLIRHLGKHVDEEVSIQGWLYNKRSSGKIQFLIVRDGTGLVQGVLVKKEAPEIFELAKELTQESAIRLRGIVREEPRSMGGYELTVTGLEIINLAQEYPISHKEHGVDFLMDRRHLWMRTPRQNAILRIRAEIEQAARDFFNQNDFTLVDSPIITPAACEGTTTLFELDYHGEKAYLSQSGQLYNEASAMAVGRMYCFGPTFRAEKSKTRRHLMEFWMIEAEAAFFDFEDNMKLQEEMVYFIVQRVLERRRQDLELLGRDISKLEAIKLPFPRLSYTEAVELLKSKGEAFEWGEDFGAPHETIISENFESPVFIHRYPTEIKAFYMKPDPEDGRVVLGADLIAPEGYGEMIGGGQRIDDLQLLEQRLEEHKLPKEAFEWYLDLRRYGSVPHSGFGLGLERTVAWICKLDHVRETIPYPRMLYRVYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2802_PSEA6
Sequence: MLNLLCAVYKSSKKADTYLYVPGRDDFSRVPESLMKMFGAPRFIMIMPIKKDRTLGQVDIQTLRDELTKNGFYLQLPPPEENLLKQHLAAQSPKD
What are the official names of this protein?
YcgL domain-containing protein Patl_2802.
Protein: SPLA_STAA8
Sequence: MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBC_PLAOC
Sequence: METLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVLKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIBB_NEIMB
Sequence: MSHISPIPEILADIKAGKMVIITDAEDRENEGDLLMAAQFVTPEAINFMIKHARGLVCLPMDGEMVEKLGLPMMTQKNGAQYGTNFTVSIEAAHGITTGISAADRALTIQTAVSPTAKPEDIVQPGHIFPLRAQKGGVLVRAGHTEAGVDLAQMNGLIPASVICEIINDDGTMARMPELMKFAEEHKLKIGTIADLIEYRSRTESLLEDMGNAPVQTPWGEFQQHVYVDKLSGETHLALVKGTPAADTETLVRVHEPFSVMDFIQANPRHSWSLPKALEHIQQAESGVVILLHRTEDGASLLDRTLPKGANQAYKWDSKSYGIGAQILAGLNVKKLRVLGQPSSFTGLTGFGLEVVGFEEAEK
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: HIS7_ARCFU
Sequence: MKKFSRKTEETEVEVVLGEELKVDTGIAFLDHMLKTLSRHSGIKLRVKAKGDLEHHVIEDVAIALGKALAGVDKKGLERFGDAIVPMDDAVAICGLDFSGRGVLVVEGTFGDGEMREEDFLHFLDTLCRNAGLNVYLSVKGSNSHHKMEAAVKAVAISLKKALTKNGNDYRSAKGVLD
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4736_VIBVY
Sequence: MRKSVIATGLALMMAVPFAANAADYVIDTKGAHASINFKVSHLGYSFIKGRFNTFSGDFSYDQNNIAASKVNVVVDTRSLDSNHAERDKHIRSGDFIDAGKFNTATFTSTKVMDKGDGKLDVMGDLTLHGVTKPITIAAEFVGAGQDPWGGQRAGFIGTTRLELADFNIPVMGTSSYVDMELHVEGIKK
What are the official names of this protein?
UPF0312 protein VVA0736.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: GRC3_CRYNB
Sequence: MSALAARRATAAAASPKPEQPESSIEEVSVSGALTLPSPKRRKTRQTSPKPRSKARYSDDVPTSRQFFQATESLAEQRTGRFSPSAPDSDGGTSSSSVGDSDEDMAQEDEFEDRREVDGERDQRKVSVAANMSSSGPFKSLDLMPVDITSQFNPKDNVNFCRITEGQLASAEMNDGHPGPGVIVSLARNESLTIAGLFLLTPLQNTLSIYSTALSPSMSSFPVYAPTSHPLPVISPASTQAPGKESDKTLLLIRENRCGIDGLRNGAVPGFSNIWLEDNGPWGLRGVHPVVGSFPVPVYPYCTPPSWSHAISSLSSSDVNLQTPFVGLVKGPKRSGKSTFARALLNNLLRRFRKVAWLECDLGQGEFGSGAVVGLWILDKPALGPPFTHPLLPSRSHYLGTYTPLTCPDEYLVAIRHLIEHYKYELQYTSEYSALHTTVHDKISTHVPLVINTQGWMKGLGEELLNVIESMAQPTRVFSFESQSEEVYSGQGWTSTPPWQATQLPYDPAYPTTEPVETEVTQTYSLETAPVSALQARYTPADLRVLSAITYFHASLHPTQSVPVTWDISSPLVCTIPWEVELGIGKALEKVYLIGEGSEGVLEEDLPIALNGAIVALAEMLGSYEDEPTVYEQGRSPPPTDLVNILGLAVIRSLSSGNSVNPGLKLQLLTPLPPSYLSRARILIKSGALELPLPGMIDWRRGGINEEGMLGKGWEEIPFLDVGGLDVIGGERRRFRKNIMRKGM
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase GRC3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UP19_PSEMZ
Sequence: RATVNGLPA
What are the official names of this protein?
Unknown protein 19.
Protein: CYTX_BOVIN
Sequence: MWGPNLGGFSDTQDATAEIQAIADQVKSQLEEKENKKFPVFKAVKFRSQVVAGMNYLIKVQVDEDDFVHIRVFESLPHENKPVALTSYQTNKVRHDELTYF
What is the function of this protein?
Strong inhibitor of papain and cathepsin L but poor inhibitor of cathepsin B.
What are the official names of this protein?
Stefin-C.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC23_RAT
Sequence: MQESQETHMSSHLDEVIAAVSVTSKNRLSNKLLQTALFQPPREKLHLCEERAKSYSSIREYKQAIQELVRCVALTKICYGDSHWKLAEAYVNLAQGYLQLKGLSLQAKQHAEKAKEILANSMESPYYNKTDIFKCSLELFYTLGKALVSLQKFKEAWENLIKAERLSKEMLQCGNIIKEEWIEIQSRIKLSFAQLYQGQKRSKEAFPYYQKALEYTETTKDEKSFECAQVLREMAGVEQALALHDASIGHFSQAHLIILSKEPSPEDAADSALSIARAAVASGMHDHHDVAEKYFQESMTYLKDSEGTEKAKFLSIQDEFCSFLQTIGQKERAAMILRESLEAKIGVFGDFSPEVAETYRILGRADLAQGNNNGAHMKLKKCVQIETFLYGSQDKKTMATQQTIDTLSKISETPVKSKQSLKAKTAFCTSVPQYVTPGKARHSAAE
What is the function of this protein?
Participates positively in the ciliary Hedgehog (Hh) signaling.
What are the official names of this protein?
Tetratricopeptide repeat protein 23, TPR repeat protein 23.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Colocalizes with EVC and IQCE at the EvC zone of primary cilia.
Protein: ANG1_BOVIN
Sequence: MVMVLSPLLLVFILGLGLTPVAPAQDDYRYIHFLTQHYDAKPKGRNDEYCFNMMKNRRLTRPCKDRNTFIHGNKNDIKAICEDRNGQPYRGDLRISKSEFQITICKHKGGSSRPPCRYGATEDSRVIVVGCENGLPVHFDESFITPRH
What is the function of this protein?
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus.  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.  Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (By similarity).  Angiogenin induces vascularization of normal and malignant tissues.  Angiogenic activity is regulated by interaction with RNH1 in vivo.  Has very low ribonuclease activity.
What are the official names of this protein?
Angiogenin-1.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: FSR3_GIBF5
Sequence: MKNTQTNGTHPIIDKKPNGTLNGDHQEYPTFSQEKLDDSIKRGIDLQVFRYPSTGINVLIAGAGLGGITCALECWRKGHNVRIIDRSPSPVWTGDNVQIQPSAILLLRHWPDMGYEIEENQYDVDMSYYRQTGERIWGPAPPMFNDPEHLPGRRGFPSVNAHSRIKLYRAFLKQAERVGIYVEWGCKVVEYWEDVEGHAGGVVLENGEKRTADIVVAADGLRTKSMTIVPGMPDQLTTSGKAIYRAGYPVEHALKDPTVREMWNFKPEDKPIWQFWLGNGSHNMMCLTHDLAFWSFIHSHAESASESWIPDIDPAEVITEMEKNDAVHPAIAALIRTAPKGSVVNWQLKFRDPHEQWTSPGGHVVQLGDAAHAFLPTSGNGATQAIEDGVTLATCLQLAGKAQAANATKVYNKLRFQRVSCGQKMGFVNQQLKQHTDWDAIMKNPALIRSRYPKWVWSHDPEAYAYEKFAEALTHVVSGGRVPLVNTNFPKGHKYRHWTMKEVQEQIKAGQKLEDLQDGDWS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of fusarubins, highly pigmented naphthoquinones responsible for the coloration of the fruiting bodies (PubMed:22492438, PubMed:23825955).  The non-reducing polyketide synthase FSR1 is responsible for the condensation of seven acetyl-CoA units to yield a haptaketide (PubMed:22492438).  After rings A and B are formed by aldol-type cyclization, the PKS-derived product is released as 6-O-demethylfusarubinaldehyde (PubMed:22492438).  Then, two hydroxyl groups at C-5 and C-10 are incorporated by FSR3, and simultaneously hydroxyl groups at C-6 and C-8 are methylated by FSR2 (PubMed:22492438).  The aldehyde is, on the one hand, reduced by FSR3 to 8-O-methylfusarubin alcohol, which equilibrates mainly with 8-O-methylfusarubin and only small amounts of 8-O-methylnectriafurone (PubMed:22492438).  On the other hand, the aldehyde can be oxidized to form 8-O-methylfusarubinic acid, a reaction driven by FSR3 equilibrating with 8-O-methylfusarubinlactone, finally resulting in 8-O-methylanhydrofusarubinlactol after a further reduction step and loss of water (PubMed:22492438).  8-O-Methylfusarubinic acid can also undergo decarboxylation, resulting in 8-O-methyl-13-hydroxynorjavanicin after another hydroxylation step at C-13 (PubMed:22492438).  Both steps are most likely also accomplished by FSR3 (PubMed:22492438).  No enzymatic function has been determined so far for either FSR4 and FSR5 (PubMed:22492438).  Their deletion does not alter the product spectrum, but the possibility that they catalyze specific enzymatic steps during perithecium development cannot be ruled out (PubMed:22492438).  FSR4 might possess a regulatory function in the biosynthesis of fusarubins (PubMed:22492438).
What are the official names of this protein?
FAD-dependent monooxygenase fsr3, Fusarubin biosynthesis cluster protein 3.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: PTR2_SCHPO
Sequence: MSSIEEQITKSDSDFIISEDQSYLSKEKKADGSATINTADEQSSTDELQKSMSTGVLVNGDLYPSPTEEELATLPRVCGTIPWKAFIIIIVELCERFAYYGLTVPFQNYMQFGPKDATPGALNLGESGADGLSNFFTFWCYVTPVGAALIADQFLGRYNTIVCSAVIYFIGILILTCTAIPSVIDAGKSMGGFVVSLIIIGLGTGGIKSNVSPLMAEQLPKIPPYVKTKKNGSKVIVDPVVTTSRAYMIFYWSINVGSLSVLATTSLESTKGFVYAYLLPLCVFVIPLIILAVSKRFYKHTPPSGSIFVRVGQVFFLAAQNKFNLEKTKPSCTTTVGRVTLKDQWDDLFIDELKRALRACKTFLFYPIYWVCYGQMTNNLISQAGQMQTGNVSNDLFQAFDSIALIIFIPICDNIIYPLLRKYNIPFKPILRITLGFMFATASMIYAAVLQAKIYQRGPCYANFTDTCVSNDISVWIQIPAYVLIAFSEIFASITGLEFAFTKAPPSMKSIITALFLFTNAFGAILSICISSTAVNPKLTWMYTGIAVTAFIAGIMFWVCFHHYDAMEDEQNQLEFKRNDALTKKDVEKEVHDSYSMADESQYNLEKATAEEEIMKST
What is the function of this protein?
Uptake of small peptides.
What are the official names of this protein?
Probable peptide transporter ptr2, Peptide permease ptr2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: GCNT4_DANRE
Sequence: MRRCAVLHRLRCKFYVFVVSLFVVVKLVYLKISMDNSIYIEPYGVTRRSLKPQPLDGINCTAIYDLEPVEIGKSLEMRRKKIVEVDDGRIASFTADCKSYIEQRRYNEVLVTDEECNFPIAYSLVVHKNSAMVERILRAIYAPQNIYCIHYDQKSTKDFIAAMKNLESCFPNVFIASKIESVQYAHITRLKADLNCLSDLLSSEVKWKYVINLCGQDFPLKSNYELVTELRKLNGANMLETSRPSKVKKQRFQFRYQLKDVSYEYQKMPVKTSIAKDPPPHNIEMFVGSAYFVLSRDFVTYVMNNQLAKDFLQWSVDTYSPDEHFWASMARVPGVPGELARSEPDVSDLKSRTRLVKWNYLEERLYPKCTGTHRRSVCIYGAAELRWLLEDGHWFANKFDPKVDPVIIKCLEEKLEEKQLQQCLRRVS
What is the function of this protein?
Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RECO_KLEP7
Sequence: MDGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSNLKGALQPFTPLLVRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYVNELISRVLEHETRFSELFFDYLHCIQALAGASGSPEPALRRFELALLGHLGYGVDFLHCAGSGEPVDDTMTYRYREEKGFIASLVIDNNTFTGHHLKALASREFPDVDTLRAAKRFTRIALKPYLGGKPLKSRELFRQFMPARKARADNTNND
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL14_STRP8
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SUCC_STAAN
Sequence: MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: KTHY_RABPU
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPSNTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVTFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ATPA_CUSGR
Sequence: MVTIRADEISNIIRERIQHYTKKINILNTGTVLQVGDGIVRIYGLDEVMAGELIEFEEGTKGIALNLESKNVGVVLMGDGLRIKEGGSVKATGRIAQVPVGDAYLGRVINALATPIDGRGEILSSEFRLIDSPAPGILSRRSIYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQSKNVICVYVAIGQKASSVAQVVTTLQEKGALQYTIVVAEMADSAATLQYLAPYTGAALAEYFMYKERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSKLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGLRPAINVGISVSRVGSAAQIKAMKQVASKLKLELAQFAELEAFAQFASDLDQASQNLLARGQRLRELLKQSQSAPLTTAEQIMSIYAGINGYLDSLELGQIGKFLRELSDYLKVNKPRFQEIINSTKTFTEEAEAILKDTIPSEKDRFLLEEKI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, plastid, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: 4EBP1_RAT
Sequence: MSAGSSCSQTPSRAIPTRRVALGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVAKTPPKDLPTIPGVTSPTSDEPPMQASQSHLHSSPEDKRAGGEESQFEMDI
What is the function of this protein?
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.  In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation (By similarity).  Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways (PubMed:7939721).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: LEUD_XANOM
Sequence: MTPFTQHTGLVAPLDRANVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDIGEPGRDNSTRPLNPEFVLNFPRYQGASVLLARENFGCGSSREHAPWALDEYGFRAVIAPSFADIFYNNSFKNGLLPIVLAEAEVDALFEQCLANEGYQLTVDLAAQRVRRPDGVEYSFDIDAFRKHCLLNGLDDIGLTLQEADAIGRFEQDHRARQPWLFGALQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GP27_BPSP1
Sequence: MSITAMDAKLQRILEESTCFGIGHDPNVKECKMCDVREQCKAKTQGMNVPTPTRKKPEDVAPAKEKPTTKKTTAKKSTAKEEKKETAPKAKETKAKPKSKPKKAKAPENPNLPNFKEMSFEELVELAKERNVEWKDYNSPNITRMRLIMALKASY
What is the function of this protein?
Required for late gene transcription and DNA replication.
What are the official names of this protein?
Gene 27 protein.
Protein: DAPF_RHIME
Sequence: MGDQVQFARMNGLGNKILVVDMRGRKDRVTPQAAIALNADPATEFDQIMAIHDPKSAGTDAWIDIVNSDGSMAQACGNGTRCVVQALAAETGRKAFLFHTVAGLLEAKEHDNGTISVDMGKPRFGWDQIPLAEEFHDTRRIELQIGPIDAPVLHSPSVASMGNPHAIFWVENDVWSYELDRFGPLLENHPIFPERANISIARIRSRQEMDLRTWERGAGLTLACGSAACAAAVNGARTGRTERMVTVNVPGGPLKIEWRERDDHVIMTGPAEWEWSGTVDPVTGIFARNEPESGDNGARAL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.