PharMolix/UniProtQA huggingface dataset:
Protein: C1QC_HUMAN
Sequence: MDVGPSSLPHLGLKLLLLLLLLPLRGQANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHASHTANLCVLLYRSGVKVVTFCGHTSKTNQVNSGGVLLRLQVGEEVWLAVNDYYDMVGIQGSDSVFSGFLLFPD
What is the function of this protein?
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.  The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
What are the official names of this protein?
Complement C1q subcomponent subunit C.
What are the subcellular locations of this protein?
Secreted.
Protein: SYWC_PONAB
Sequence: MPNSEPCVSPLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLLSLKMSYKAAMGEDYKANCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGELKKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ
What is the function of this protein?
T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it.  T1-TrpRS and T2-TrpRS possess angiostatic activity.  T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells.  Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity).
What are the official names of this protein?
Tryptophan--tRNA ligase, cytoplasmic, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT2_DANRE
Sequence: MRFIAFAVIFSAVYLCSSAFTHPRGEWTKLILTQHWPQTFCKMEHCKTDFSYWTLHGLWPNTGVRCNTSWHFNASLIEDILPEMEKFWPDLLEPSSPKFWNYEWTKHGTCAAKSESLNSEHKYFGKALELYHKFDLNSVLLKNQIVPSEKHYTLEDVEEAITSAYGVKPKIQCVHPGQGGQVQILGQIEICVDRDFQLMGCEKSSEDTWSNDLPTVPVSGQSGLSVCDHSMPVYYPPVQA
What is the function of this protein?
Has ribonuclease activity, with higher activity at acidic pH.  Probably is involved in lysosomal degradation of ribosomal RNA.
What are the official names of this protein?
Ribonuclease T2, RNase Dre2.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Lysosome lumen. Endoplasmic reticulum lumen. Secreted.
Protein: CCD86_PONAB
Sequence: MDTPLRRSRRLGGLRPECPESLTSVSRTRRALVELESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGSGLESPQGQPEPGAGSPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEVPKCSQDQGVLASELAQSKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSLAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQRPAAKI
What are the official names of this protein?
Coiled-coil domain-containing protein 86.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURG_RHIEC
Sequence: MSKGIVLLAAGGTGGHVFPAEALAFKLKERGYSVHLVTDSRAERYAGKFPAEEIHVVPSATIGSKNPVAVARSLWTLWSGMRAAKRLIQRLKPVIVVGFGGYPTVPPLLAATRLGVASMLHEQNAVMGRANKALAPRVKAIAGGFLPESGDVFSDKTVATGNPVRPAILAAAEQPYLPSHPGEPFNLVVFGGSQGAQYFSKAMPTAISLLDDGLRARLRVTQQVRPEDMEMVSGCVAKLEMGADIAPFFNDMAERLAQAHLVICRSGASTVSEISVIGRPAILVPYPHALDHDQAANAAALAATGGAKVIPQSELSPERIASILSHVMNDPDKLSHMAAAAKLAGKPDAANLLADMVEAIAAGKTVSEFKRTRA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS3_GEOMG
Sequence: MIQIDFQKMGGLIPAIIQDHESGEVLMVAFMDEKTLNLTLESGKTWFFSRTRNKYWMKGEESGNTQEVIEVLTDCDADSVVIKVKQNGPAACHTGNRSCFYVRWEGGQWVEHSNPLFDPKEVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_TRIV2
Sequence: MRVKICGITQPQQSVAIASLGATALGFICVPSSPRYVTAAQIWAAVAPLPKNIDKIGVFANSSIAEIKQTVIDCGLTGVQLHGDETPEFCDQLRRSLPQVEILKALRVRSLEHLEQAIIYTQYINTLLLDAYHPQQLGGTGQTLDWQMLHKFHPSCPWLLAGGLTPDNILEALSQLNPDGIDLSSGVERKPGDKDLDKVALLFEKLGSRN
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: Y096_METJA
Sequence: MEVKAMEIFKKYLSLNIPKKILITYFLCWAGFLFSFSVGKFLLYLSSILKSNFISEPAKLAQSVGTAKFNAVSSAVSNTVGVKNAYLTYALSYIVSNFMGCLIIMFALGALAYLYKKDLEKAKTLEEKEELFKCYQKYLLILFIFTVINPLTGLIGVNLQYSDLIAVLPHGFFEFFGFATAVVVGVELSNKILPIVKREITSKKIVILIACSFIFIFIAGMLEPIDWFIYSYAKAYGIPLLAAFATGYKNLFLYLISMLFKS
What are the official names of this protein?
Uncharacterized protein MJ0096.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSD_CHLPM
Sequence: MFTPYGMSTLVKLAAVSVGTLLFSILLPLQAAIPVGSAAAIFLIFSLWFFRDPNRSLPPGKGIVIAPADGTVMSIKACSHPFTGNGSSIISIFMSPLNVHVNRIPVTGTVTLLQHHPGSFSMAFDEKSGEENERMEIGIESNGMKLHFTQVAGFLARRIVCPLSLNEPVTAGKRFGMIKFGSRVDIVIPAGWLPEVKRGAKTRAGETIIARLATTAGNG
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS19_BRAHW
Sequence: MSRSIKKGPFVDKNLFKKIQAGDNKHQIKTYSRASTIIPEMIGFTINVHNGKTFVAVYIQENMIGHKLGEFAPTRKFISHAGAAKVGKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MTNA_CROS5
Sequence: MNTIYPVIWSNNKVLLIDQTSLPSRYTLVEISRYEDMAKAIKTMIVRGAPAIGVAAAYGMYLGARDIQTQDRETFLKHLDKIAQILRQTRPTAVNLFWAISRMLKTAYETLGTVEEIKKILLETAQKIQEEDLQTCQAIGHNSLSILPTNPEKLTILTHCNAGALATAGYGTALGVIRSVWTAGRLNRVFADETRPRLQGAKLTAWECVQEKIPVTVISDNMAAHCMQKGLIDMVVVGADRIAANGDTANKIGTYGLAVIAKMHQVPFYVAAPLSTVDFSLETGDLIPIEERDPSELYQIGNTVIYPDGVDYYNPAFDVTPADLITGIITEQKTVNPKELITLKG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: KDM8_RAT
Sequence: MSEDTTEPLVGPSTLWKDLRALLPDTEEELKLDLSEKVDRSMATLLRQALGLFYEGRWQKCLQASEAVLDYSWEKLNTGPWRDVDKEWRRVYSFGCLLKTLCLCQAPQKATAVAEALRVCDMGLLMGAAILGDILLKVATVLQTHLLPRKQPACGPHQDQPATKKAKHDASSTPDVVLDREVPRLRCPPLQHFKKHFLVPGRPVILEGVADHWPCMKKWSLQYIQEIAGCRTVPVEVGSRYTDEDWSQTLMTVNEFIHKYILSEAKDVGYLAQHQLFDQIPELKQDISIPDYCCLGNGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVLGRKYIRLYSPQESEAVYPHETHILHNTSQVDVENPDLEKFPKFTEAPFLSCILSPGDTLFIPAKYWHYVRSLDLSFSVSFWWS
What is the function of this protein?
Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase.  Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation.  Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4.  After initial cleavage, continues to digest histones tails via its aminopeptidase activity.  Upon DNA damage, cleaves the N-terminal tail of histone H3 at monomethylated lysine residues, preferably at monomethylated 'Lys-9' (H3K9me1).  The histone variant H3F3A is the major target for cleavage.  Additionnally, acts as Fe(2+) and 2-oxoglutarate-dependent monooxygenase, catalyzing (R)-stereospecific hydroxylation at C-3 of 'Arg-137' of RPS6 and 'Arg-141' of RCCD1, but the biological significance of this activity remains to be established.  Regulates mitosis through different mechanisms: Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with RCCD1.  Possibly together with RCCD1, is involved in proper mitotic spindle organization and chromosome segregation.  Negatively regulates cell cycle repressor CDKN1A/p21, which controls G1/S phase transition.  Required for G2/M phase cell cycle progression.  Regulates expression of CCNA1/cyclin-A1, leading to cancer cell proliferation.  Also, plays a role in regulating alpha-tubulin acetylation and cytoskeletal microtubule stability involved in epithelial to mesenchymal transition (By similarity).  Regulates the circadian gene expression in the liver (By similarity).  Represses the transcriptional activator activity of the CLOCK-BMAL1 heterodimer in a catalytically-independent manner (By similarity).  Negatively regulates the protein stability and function of CRY1; required for AMPK-FBXL3-induced CRY1 degradation (By similarity).
What are the official names of this protein?
Bifunctional peptidase and arginyl-hydroxylase JMJD5, JmjC domain-containing protein 5, Jumonji C domain-containing protein 5, L-arginine (3R)-hydroxylase KDM8.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with trimethylated 'Lys-9' of histone H3 (H3K9me3).
Protein: RUTC_ECO1A
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: ADHX_DROME
Sequence: MSATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY
What is the function of this protein?
Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, Octanol dehydrogenase, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein: PIM3_COTJA
Sequence: MLLSKFGSLAHICSPASMDHLPVKILPPVKVEKEPFDKVYQVGSVLGSGGFGTVYAGSRTADGLPVAVKHVVKERVTEWGTIGGVMVPLEIVLLKKVGSGFRGVIKLLDWYERPDGFLIVMERPELVKDLFDFITEKGALDEDTARGFFRQVLEAVRHCYGCGVVHRDIKDENLLVDLRTGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLYFRRRISPECQQLIKWCLSLRPSDRPTLEQIFDHQWMHKSEVVKSEDCDIRLRTLDTDVSSTSSSNESL
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation.
What are the official names of this protein?
Serine/threonine-protein kinase pim-3, qpim.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECEL1_RAT
Sequence: MEAPYSMTAHYDEFQEVKYESRCGTGGARGTSLPPGFPRSSGRSASGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGTGGACPEGCPERKAFARAARFLSANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPTGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAADRPGAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEGSEKVLAAYKVFMERLLRLLGADAVEQKAQEILQLEQRLANISVSEYDDLRRDVSSVYNKVTLGQLQKITPHLQWKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSPPFREALHELAKEMEGNDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAQTKAAARAKLQYMMVMVGYPDFLLKPEAVDKEYEFEVHEKTYLKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLHKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHRLKYTHNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPVHKCSVW
What is the function of this protein?
May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.  Cleaves the synthetic substrate Z-Gly-Gly-Leu-pNA and releases pNA.  May protect against C2-ceramide-induced apoptosis.
What are the official names of this protein?
Endothelin-converting enzyme-like 1, Damage-induced neuronal endopeptidase, Xce protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y2657_METHJ
Sequence: MINILEVNETNNMIEQEKLDVRTITLGISLLDCCDASLDTLNQKIYAKITRLARNLVSTGREIELEYGIPIVNKRISVTPIALIAGSACQSPEDFVSIAQTLDKAAADMGVNFIGGYSAIVSKGMTWTDELLIRSIPHALSATERVCSSVNIGSTKTGINMDAVRLMGQIIKETAEATQEQNSLGCAKLVVFCNAPDDNPFMAGAFHGISEADAVIHVGVSGPGVVKHALESVRGKDFEVLCETVKKTAFKVTRVGQLVAQVASERLGVPFGIVDLSLAPTPSVGDSVAEILEEMGLESVGAPGTTAALALLNDQVKKGGVMASSFVGGLSGAFIPVSEDQGMIDAVIRGSLTIEKLEAMTCVCSVGLDMIAIPGSTPASTISGIIADEAAIGMINQKTTAVRLIPVIGKDVGDMVEFGGLLGHAPVQQVNTFDCSKFINRGGRIPAPIHSFRN
What are the official names of this protein?
UPF0210 protein Mhun_2657.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: YDD3_SCHPO
Sequence: MGGIGKKRVKKRTHLKADPIQEAAIPKSMVIRSGASEVGRSLSLLTRDLRHMMEPHTAIRLKERKANKIKDYLTMAGPLGVTHLLVLSRTDNNANLRIIRAPRGPSLHFRIHEYMLNKDVRRLQKNPKSPTTEFLTPPLLVMNHFNQNSSKDSPHEALLTTTFQNMFPPISVQHTNINSVKRVLLLNRRDDGYIDLRHFIISTKPVGISRPIRHLLKGEKKDSDIPDLHNVRDISDYVLHGDGISGAASDSEIEEDATVEIDRPVPTKTEENLLSASQLLKPKQQAIKLIEIGPRMTLELIKITEDAMGGKVLYHSHVHKSKEEIKQQDNFHEQSRALKEKRKKEQDENVRRKRENKKRRKDQKKEGITSSNKNDDSGNEGSSAYSDTE
What are the official names of this protein?
Brix domain-containing protein C1B9.03c.
Protein: SYP_CROS8
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPAELWQESGRWEQYGPELLRFVDRGDRAFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTTQESLQQTYDAMYEAYSKIFTRMGLDFRPVQADTGSIGGSASHEFQVLAQSGEDDIVFSDTSDFAANIELAEAVAPLTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAAEGSEFPLVALLVRGDHELNEVKAEKLAQVASPLTFATEAEIRAAVNAGPGSLGPVNMPVPVVIDRSVAAMSDFAAGANIDGKHYFGINWDRDVATPQVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSDALKASVQGEDGRNQVLTMGCYGIGVTRVVAAAIEQNHDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYAELRAKGIDVLMDDRKERPGVMFADMELIGIPHTVVIGDRNLDNDEIEYKYRRDGEKKMIKTGDILDYLVANVKR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCRB_ECOLI
Sequence: MESIQPWIEKFIKQAQQQRSQSTKDYPTSYRNLRVKLSFGYGNFTSIPWFAFLGEGQEASNGIYPVILYYKDFDELVLAYGISDTNEPHAQWQFSSDIPKTIAEYFQATSGVYPKKYGQSYYACSQKVSQGIDYTRFASMLDNIINDYKLIFNSGKSVIPPMSKTESYCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYLLTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAKEQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDEERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNFLLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDGTSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLGDS
What is the function of this protein?
Recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue.  Binds to DNA containing methylated cytosines; also binds to GTP.  Isoform 33 kDa is less active than isoform 51 kDa and may play a role in regulating the activity of isoform 51 kDa by competing with it in DNA and protein binding abilities.
What are the official names of this protein?
Type IV methyl-directed restriction enzyme EcoKMcrB subunit, EcoKMcrBC, 5-methylcytosine-specific restriction enzyme B.
Protein: ACT2_ARATH
Sequence: MAEADDIQPIVCDNGTGMVKAGFAGDDAPRAVFPSVVGRPRHHGVMVGMNQKDAYVGDEAQSKRGILTLKYPIEHGVVSNWDDMEKIWHHTFYNELRIAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGFSLPHAILRLDLAGRDLTDYLMKILTERGYMFTTTAEREIVRDIKEKLSFVAVDYEQEMETSKTSSSIEKNYELPDGQVITIGAERFRCPEVLFQPSFVGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFSGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKAEYDEAGPGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.  This is considered as one of the vegetative actins.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ABCD1_DICDI
Sequence: MKTTNVKNNNNNINNTDEEIKIKNNYNQNDERLKKIKENKFDWALFKRFINIIKILYAKPVIPLTLFLILFGNGFAQTYVSKFTGILLADIYASFTSGDKVFFLSSVLKAGFAIGGSALLAAIINFIVSIMAWNWRKTLCLYIQNVYFKKSLFYKILAFDDRIDNPDQRITSDIDNFTTLLASIVSQCITGPMVVVYYTYLCYTTIDWYAPLIVYGFFFLGYLINKLVMSPMVSINYLQDKLEGDFRSLHQRIRNFSESIALYSLSKEKQHPEKRFDNNDYDHGYESDDSDQSCDESTTIINRKKNKGSQYYKNKNSTSKKINDFIDKLSGDSNDQKEELLVEEEQAKIQFEALLKNKKRVIFWQLGLNTTSDLFTYLSPIANYFIIAIPVFFLNNKSVLQPGDVTVQSYNCIMLASGFSQYINVSQSISDLSGYISRISSMIEVCKKIMEDVSLDADITKLNEKVAQTHNNDAIINTGSSGNISLNNGDSITLDDVTYFTPKGNQLYSKISINVKRGNNLLIMGPSGSGKSSLIRIINGLWPFFKGSIDRPENGDMFFLPQQPYLIFGTLEEQILYPFSKKQKRIPKSIMRELFQRFEIDYLLDRERFIKKSAQVNDLTHNWLNQLSPGEQQLIAIIRLIYHKPKFALMDESTSSIPQSLEERVYYVAKELGITIISVGHRISLLKYHSTLLRFDKDKNWYLEDIINQNNQSNNINNNNNNNTNKIAEDSVFD
What are the official names of this protein?
ABC transporter D family member 1, ABC transporter ABCD.1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DADA_AZOVD
Sequence: MRVLVLGSGVIGTTTAYYLARAGFEVVVVDRAEAPAMETSFANAGQVSPGYASPWAAPGVPLKALKWLFERHAPLAIRPTADWRQYLWLAQMLRNCTAGRYALNKERMVRLSEYSRDCLDELRAETGIDYEGRQLGTTQLFRTQRQLDAAGKDIAVLARSGVPYELLDRAGIARVEPALAGVADRLAGALRLPNDQTGDCHLFTTRLAELAAGLGVEFRFGQSVERLERDGERIVGVRIDGRLESADLYVLALGSYSPRLLAPLGIRAPIYPLKGYSLTIPIVDPAMAPTSTILDETYKVAITRFETRIRVGGMAELAGFDLSLNPRRRETLELVVGDLYPRGGDLARAEFWTGLRPATPDGTPIVGATRYRNLFLNTGHGTLGWTMACGSGRLLADLMARTRPQISAAGLDISRYGNSQENSTHVHPAPAN
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: MURC_NEIG1
Sequence: MMKNRVSNIHFVGIGGVGMSGIAEVLHNLGFKVSGSDQARNAATEHLSSLGIQVYPGHTAEHVNGADVVVASTAVKKENPEVVAALERQIPVIPRALMLAELMRFRDGIAIAGTHGKTTTTSLTASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVAEADESDASFLHLTPIMSVVTNIDEDHMDTYGHSVEKLHQAFIDFIHRMPFYGKAFLCVDSEHVRAILPKVSKPYATYGLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVVLNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYGDIKLPNGGTALLVDDYGHHPVEMAATLAAARGAYPEKRLVLAFQPHRYTRTRDLFEDFTKVLNTVDALVLTEVYAAGEEPVAAADSRALARAIRVLGKLEPIYCENVADLPQMLMNVLQDGDVVLNMGAGSINRVPSALLELSKQI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRMA_ASPFU
Sequence: MFHKEAGISHLILDIILEHALNKFDPAPDRLQGAAKNFLPIIERFVAAGTRIEACLPAFPFKSANKVYKVLGSLPDKAEELALDRLNTMCARVREVYPPGLQVAIISDGITYNDTWAYGEALRQMAAQKQFMYIVFSRIKDLLDIPLPEQMSEIVYVANCTTFRRLLLNKYERADLDIDHEIASNPDTKLTYLGYRRFLESDLKYIFPRGAHRSAHSYKRDCKYLAKQMLIRGDAFAQAIKTSYPNHLRLSIHESVAGTKLSISLLNTKTGFTTPWHCSVAQLANGEWISAPMGEFRKDDRLELVYADGRPSHFREKPREGDAFGISESTASYLQRPKRLRASEYLGATLPSVPVSPGMSSPSAASTSSSGASMQGSAATTPETHSPPTFTWSGLEIVAEDNSNNASVPYGRRLIPQIMDSLAATEPERIVFSLATFSGDSLEFRPISARTFANAIDKTAWWLHNQVGRPDSIQPVGYIGPHDLRHVLLTYACVKAGYAALFLSPKNSTEGALAVLEATKCDLWINACDVSPVPLVKEVLQKRPMNVLQLPQLDELLDAVSTDPFPYTKKFDEAINDPFCFLHTSGTTGVPKPIPWSHGLIGTMDAVRLLPPGADGDLPPWTTDWKTGDTIYSSFPMSHGAGIIMNILMPALFNLHCVFGPAGVLPNINLVDALAVSTRIDIWSMVPSLVDELGETPAVLSKLKSSKFICASGGPVSPVSAGKVNEVIRVLNLTGTTEGLFMGNLIPPREDWFWFCFHPYSGFEFKQVEPDTYEHWVHRNEHWPLFQGIFHTFPEKQSINFKDLYVRHPTKPNLWAFKGRSDDLVTEAFITTHPAIKGCLVFGTGKPQAGLLIELKDPLQKTDELLDSIWETVQQANSMSRHKNQLLRDFVAFATPDKPFCRTDKGTVKRSATLKLYADYIERFYRSRNDDLGGTFDFDMSSAHSIEDNVRKILAASLPDVQEASADTDLFALGLDSLGVFAAIKTIRAATGLGDQIGPRHIYANPTIARLSAIIALLAAAAESASDTTLCERPVDDVGAQIARMIAQHKARQSFSLNAFDYVNPNHGMGLVLYFPIRDGVSYEQVFANLQAGLNRTFDLIPALSGKMTDCSEQGIGYTKGDLCVTIPPLAKADSARNRLVYKDLSAVLPSFDDLRKGGFAPSAFSDTLANFVSGGCILAVDLNHCCLDGLGAMVALKAWAENCRYLQGDQSATCGWYDPESFNHSLPEILHRQEGWARPLHEIDPGTWGFLPFFPPEDEETNPRCEKATEGSLPARPIFPLHPVWPLPRAERCLKTTMFLVTPEKLELLQQDVIADPATNGITPSISDIVQAFFWRAAIKARYRVATEIRKQKFSPDAVSILELPTDTRPHFSSRLPPTYMGSMLILNRTSMPIETLCSAETSIAKVALLLRQSAARITPSLVHDAFTLLQSLPGHRRFSTANMGLEHMHAMISNMLLFPTSEIGFGDAFFANGGVPETMRPQLERGNGRFRFLAVFPLRKDGGVELVLGTHREELEMLVTDEEFTRYARMVDTCC
What is the function of this protein?
Isocyanide synthase-NRPS hybrid; part of the crm gene cluster that mediates the biosynthesis of a yet unidentified copper-responsive metabolite.
What are the official names of this protein?
Isocyanide synthase-NRPS hybrid crmA, ICS-NRPS crmA, Copper-responsive metabolite biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NRP synthetase family.