PharMolix/UniProtQA huggingface dataset:
Protein: MCLN3_HUMAN
Sequence: MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK
What is the function of this protein?
Nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events.  Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (PubMed:18369318, PubMed:19497048, PubMed:19522758, PubMed:19885840, PubMed:29106414).  Mediates release of Ca(2+) from endosomes to the cytoplasm, contributes to endosomal acidification and is involved in the regulation of membrane trafficking and fusion in the endosomal pathway (PubMed:21245134).  Does not seem to act as mechanosensory transduction channel in inner ear sensory hair cells.  Proposed to play a critical role at the cochlear stereocilia ankle-link region during hair-bundle growth (By similarity).  Involved in the regulation of autophagy (PubMed:19522758).  Through association with GABARAPL2 may be involved in autophagosome formation possibly providing Ca(2+) for the fusion process (By similarity).  Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events (PubMed:19885840).  Possible heteromeric ion channel assemblies with TRPV5 show pharmacological similarity with TRPML3 (PubMed:23469151).
What are the official names of this protein?
Mucolipin-3, Transient receptor potential channel mucolipin 3, TRPML3.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane. Note=Recycles between the plasma membrane and intracellular compartments by a dynamin-dependent endocytic pathway (PubMed:19522758). Under normal conditions, only a very minor proportion is present at the cell membrane (PubMed:19522758). In the cochlea located at the base of stereocilia near the position of the ankle links (By similarity).
Protein: MTD1_DICDI
Sequence: MEEYKEIMQNKKGKVDVTPIANFFREEVKQQITKNCWKPRVVAFLTSDDQGAIDYSKWTKLACQKDGIEFILKRVERVDLEDLIIEANNDSCVHGILVYYPVFGGMMDSYLQDVVSPTKDIEGLSTQNRFNLYHNIRFMDGETATKKCVIPCTPLAMVKIIDNLGIYDKSLAMGEHLKGKTVTIVNRSEIVGRPLAAMLANDGAIVYSIDINGIIIFQSGKRHGTIKMSETNVTREEAISKSDILILGVPSPNYKVNSDLIQDGTIVINFAGCLNVDESIQEKSILVPTIGKVTIAMLERNLLRLFNNQISNK
What is the function of this protein?
Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
What are the official names of this protein?
Methylenetetrahydrofolate dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BRN2_ARATH
Sequence: MGSSSNGGVPPGFRFHPTDEELLHYYLKKKISYQKFEMEVIREVDLNKLEPWDLQERCKIGSTPQNEWYFFSHKDRKYPTGSRTNRATHAGFWKATGRDKCIRNSYKKIGMRKTLVFYKGRAPHGQKTDWIMHEYRLEDADDPQANPSEDGWVVCRVFMKKNLFKVVNEGSSSINSLDQHNHDASNNNHALQARSFMHRDSPYQLVRNHGAMTFELNKPDLALHQYPPIFHKPPSLGFDYSSGLARDSESAASEGLQYQQACEPGLDVGTCETVASHNHQQGLGEWAMMDRLVTCHMGNEDSSRGITYEDGNNNSSSVVQPVPATNQLTLRSEMDFWGYSK
What is the function of this protein?
Transcription activator.  Together with BRN1 and SMB, regulates cellular maturation of root cap.  Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis.
What are the official names of this protein?
Protein BEARSKIN2, NAC domain-containing protein 70, ANAC070.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDI_BRUC2
Sequence: MSLIVYFSSRSGNTHRFVERLGVRSSRIPLEASGALQVREPFVLVTPTYGGGSTKGAVPNPVIRFLNDADNRALIRGVIAAGNSNFGEAFCIAGNIISAKCGVPYLYRFELLGTAEDVGNVRNGMEQFWTRQTQA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: HUTI_BURM1
Sequence: MKPTVWHHLRLCPHGHPDETIDDAAIAVDETGAIVWLGACAALPHGYAHWRREDLHGAWVTPGLVDCHTHLVYGGTRADEFAQRLAGVSYEEIARQGGGIVSTVRATRAADETALFVQAAARLQPLLAEGVTAIEIKSGYGLDLASERKMLRVARQLGERFPVSVYTTFLGAHALPPEYAGRADAYIDEICERMLPTLADEGLIDAVDVFCERIGFSLAQTERVFEAATRRGLPVKLHAEQLSDAGGTALAARYHALSADHLEFLDEAGIEAMKAAGTVAVLLPGAYYFIRETQLPPIDLLRRHGVPIALATDHNPGTSPLESLLLTMNLGCTLFRMTVPEVLQGVTRHAAAALGRADRHGALEVGRQADFAVWSVGSLAELAYWIGRPLCEQVVRGGTTVFRRMIG
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_STAAW
Sequence: MMIIVMLLLSYLIGAFPSGFVIGKLFFKKDIRQFGSGNTGATNSFRVLGRPAGFLVTFLDIFKGFITVFFPLWLPVHADGPISTFFTNGLIVGLFAILGHVYPVYLKFQGGKAVATSAGVVLGVNPILLLILAIIFFIVLKIFKYVSLASIVAAICCVIGSLIIQDYILLVVSFLVSIILIIRHRSNIARIFRGEEPKIKWM
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOLB_SERP5
Sequence: MKQAFRVALGFLILWASVLHAEVRIEITQGVDSARPIGVVPFKWAGPGTPPEDIGKIVGADLRNSGKFNPIDVARMPQQPTTASEVTPAAWTALGIDAVVVGQVQPGADGGYLISYQLVDTSGSPGTVLAQNQYKVTKQWLRYSAHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGKFPYELRVADYDGYNQFTVHRSPEPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANGAIRQIASFPRHNGAPAFSPDGSRLAFALSKSGSLNLYVMNLGSGQITQITDGRSNNTEPTWFPDGQSLAYTSDQGGRPQIYKVSASGGASQRLTWEGSQNQDSEVSSDGKFLVMVSSNSGAQHIAKQDLGSGAVQVLTGTFLDETPSIAPNGTMVIYSSTQGMGSVLQLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DHP2_CAEEL
Sequence: MSLLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGAVVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQGSGQFIPLAPDSQIVFSAVDNRKKAMEPVKIDRIPYEPSALQTPDANANIVVKAPVRAAIPPGGASSIQF
What are the official names of this protein?
Dihydropyrimidinase 2, CeCRMP/DHP-2, UlipA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: TYSY_ECOLC
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGNTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_BARVU
Sequence: MEKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSILFENVDYEKKYSSLIVKRLILRMYEQNRLIIPTKNLNQNYFFGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFEGKQLKKSYNLQSIHSIFPFLEDKLSHFNYVLDVVIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYCNWKDFSIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSTSYEVLFERILFYGKIQHFFKVFVKNFPAILGLLKDPLIHYVRYHGRCILATKDTPLLMNKWKYYFVNLWQCYFSVWFQSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKAVWTDSSDSDILNRFVRISRNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: POL1_RRVC
Sequence: MGWTCPVQGCMYSRSTWSNRGLKEDGLSSTMRCPGAMCGAMLVRSEPVQAPKATVVPQTPVTAVRPKRTVVSATPLRKQDCVVVVEVGFPALLSLEYPALAGRARHTGEFDSALLARKPSNGGTARAPTGWFKPRVVRTQPAKKALPSWVSEARRLIKGALEGSNAFGPRYCREKFPKARLVWVLGMLSKSSPPSVAIGRQLKKSFLALQARIARALAKKQSARAARRQEACRKIRLALQQARGIAALERQQARQLSGAGLYSVRLCTKRALSPIVEVPKRHKKKAISLPSPVSVQEFPEGLVGPNFWETSGLLNCVASPQRREDLVFPVYGIDSCRTDPEYFVVGPKSPSKIMGDTKPRLPTCPAEALNLLWASNLFEDWELDIIGQMVSDGLLTSQAFLDGCTLVSYYGQEQMVDSFHCLLQDPVPAEVAEALAVDVQALDFDAVFGCGISDFLRGTRDAMKGWIMDPVIAKSTTWCNTIIDKVRALFDQYFAPFHKIIDGMSYVNSLWAKCKEWAQSVLKNGSQLFSVMWETHCVSFVIIITCACTLLVENVLKELRLISRVGTLTSCVISGALGILGCGYILAKCEDLAVVSASIRAFLGVLLCPPTMEAVDLNQSLIPEEIQATSWTGVDRVLGALNAVGSGLTGFNTDTIIYWGRFAQSFDGMRRGKDAVCALAACLFEKLGTVYNRVTGKEAAFFHELSSLVSIDVQGWLNSSRRVMAESIAFAKSDAVAFATVERLINDGETIQLTAASAPKSHSMQFGQILAERLRELRTLRNDMAHAGSFEGRRCVPFWLYIYGPPGVGKTTTMHEFSQALLTAFEFPSDSLTSKSATDKYWSLYRRQALVQIDDLGAISESGMEQEMMNIVSSATYNPTMAVANEKTTLFDSKFIVSTSNNYSAGTDAKIHDRKAFNRRRRVVIKTRGKAGVAFNPHDSTAAAEFCVVERDDRAETPIWVQSGEAPDDKELYWMDFRTTVAYVIEQARIHHNAEDIEQAQYSMKHSRTRQLYQVCENYIGEVKMSVANFVPGDMLGAWNLEPKGRFFYSCVDGRVYSYDPEQKAHDEGPVDKALDFEQICLEKLSYTLQADIQGGPKSATAGIFLRSMVSGECAVESVDKLNRSASREHLIFFKNLSLADRVYLRLVQKRILQLAMVGDPLGLRSYTVMMEGFQNSYNYVKENGGRLLLILCSCMLLGIACYTFFNALAILIGGTSVAAGAAAMVDIGACGSTSTYASEYGAKMGRRNMPHRSREIPAVWSEETGHDEKWQLCGLLETCRSDMPAVHVNLVPGNKFAITKHQAQAIPDGSSVGLSVAGRSFRTFQWRASALTEYAESEICTYFDSRIPSLGKQAMKMYSDSDLDALNVKYFSTRTLHFRLVDDQVEKRHWDADACVISTPKTIVSTINGVIYRQEIPTAITYRRESVKHDCGALVFTEVRGKPKAVGMLVGTLGGTTYVCKFPHIEVDAFACVPDIRGFNLEAGVSTLGYSKLGWLDRRHQPHNSEKTEFVPIPEKYHMDDVPCKIPAVLSAKDPRLADIPQCMGYDPYKQGMEKFAHPMQEIDEQLLATVCDEIAQEFHDVGVRGRMVSMDEAINGHHKYEIPSFYVEGASTRELNELRTSCSAEVWCCDPRSDIEFEYPRIIPGPVESKWKCESTCCGCTFKSGGTEAIISFVKARSPCCEEIFFDGLDLTTSEGYPLFLDRPAGAKGKERFFEGSENQKFLIPDCPLDVQLKKGIEETHLGTPQLIIKESAKDELLKEGKVLPSEGMPGTRLFSICPAWYNIVVRQHFVYIAESVRKRRRTLSSQVGIVVGSREWDDLAARLRSKKNDKMYCCDYSKFDGLMTPQIVHAITNIYERMFSGNDGMSQFRQNLLMGICNRISICGSQVYRVEAGMPSGFALTVDFNSIFNEILVRCAYRSLVPEIERPFFSNNVVLIVYGDDNVLGIHPNIESAFNGNAIKAYMKEELGIKITDGADKLSPVICARPLEQCEFLKRTWRKDRQYGLYRAPLVETSIYSCLRYVRLQNYDWQAPLLQNVQGSLYEASLHGPDMHARIYKHFATHFPKWVEEHELYTYEQCRTRFIAAKNGDFNFHPASAQMGHVFSQQTEIQELSQSQNPKRCFQLHPKIHICGPGHNEQDCFYVDVRVKGKITKGKGFHHAPVFSAGSGQLGTVKWASSFRSSSACPMRDLAVDAFKRGECVYFRDNGELINAWLAAINFGMSINADGLDGLLQVYRNQGPTHLDDLSFYFEGGVVGVPAPAHLMVYGTDTSILNRLCPKTVLESAPPPGRSSNVSERSQVQTFLHMSPKPCFITLKGSGKVCHGLRCNNSCRGHISCTDVVRNSAANQRAAMLDVLRRGCYNIQ
What is the function of this protein?
Picornain 3C-like protease is a thiol protease that cleaves the P1 and P2 polyproteins.
What are the official names of this protein?
RNA1 polyprotein, P1.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA1 polyprotein family.
What are the subcellular locations of this protein?
[Viral genome-linked protein]: Host endoplasmic reticulum lumen. SUBCELLULAR LOCATION: [Putative ATP-dependent helicase]: Host endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: METK_FRATM
Sequence: MSKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTSAWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDIAQGVDRGSLEDLGAGDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDKPKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYRKTSNYGHFGRELPEFTWEKIDKADILKSAARI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGKY_WHEAT
Sequence: MATKRSVGTLGEADLKGKKVFVRADLNVPLDDAQKITDDTRIRASIPTIKYLLEKGAKVILASHLGRPKGVTPKFSLKPLVARLSELLGLEVVMAPDCIGEEVEKLAAALPDGGVLLLENVRFYKEEEKNDPEFAKKLASVADLYVNDAFGTAHRAHASTEGVTKFLRPSVAGFLMQKELDYLVGAVANPKKPFAAIVGGSKVSSKIGVIESLLAKVDILILGGGMIFTFYKAQGLAVGKSLVEEDKLELATSLIETAKSKGVKLLLPTDVVVADKFAADAESKIVPATAIPDGWMGLDVGPDSIKTFAEALDTTKTVIWNGPMGVFEFEKFAAGTDAIAKQLAELTGKGVTTIIGGGDSVAAVEKAGLADKMSHISTGGGASLELLEGKPLPGVLALDEA
What are the official names of this protein?
Phosphoglycerate kinase, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLD_RHIME
Sequence: MAKALVLEKKGQLSLRDIPVRRDLSPTDVLIGIRTVGVCGSDVHYYTHGKIGPFVVNEPMILGHEAAGVVLEVGSQVRHLKKGDRVCMEPGIPDLSSRSSKLGIYNVDPSVRFWATPPVHGCLTPEVVHPAAFTYRLPDHVSFAEGAMVEPFAIGVQAALRAGIRPGDVGAVMGAGPIGMMTALAALAGGCSKVYVADLAQPKLDVIGAYEGIETINVRQQAVSEALAGATGGWGADVVFECSGAAPAILALPSLARPGGTVVLVGMPVEPVPFDIVGMQAKELRIETVFRYANVYDRAIELIASGKVDLKPLISATIPFDESIAAFDRAVEARPTDVKIQIEMPA
What are the official names of this protein?
Putative D-xylulose reductase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RECF_COLP3
Sequence: MSVARLTTYNFRNLSSVAIDLHPKLNFFIGNNGSGKSSLLEALFFLGHGKSFRTSKVEHLACYETDNFVVSIKDVNDLQLGLSKNLQTGVTLIKINGERHARLSELAKNIAVQIVTPESFKLFFGGPKERRRFIELGMFHVKHDSSKQWREFNRVLKQRNACIRHNLDKATFDYWTGLFCQLSEQVAEVRSQYITNLISELPYWLEILLPNIADKVTVQYLQGWPQKKNLMDSLNDSHEREQAFGYSIYGAHKFDVKFLIAKQALESQLSRGQQKLFLLALTFAQAKLIARVNRVKPILLIDDIGAELDINSRESLSQALSILDCQVIITAIEEGVLQPFIDDVSVADKESSKKTKYHMFHVKHGGILPVNNSVKIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_SHISS
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM24_XENLA
Sequence: MRLTLLLEMAAKLKLPHDYRFGMSRPSTLAAKRRNPPGKRRSKVFVEPVSKEEWQYFRGDTVEVLHGKDAGKQGKVTQVVRARNWVVVDGLNTHFRYVGRTDEYRGTYVASEGPLLLNQVSLIDPTDRKPTEIEWRYTEEGERVRVSARSGRIIPKPVLQRRDGIIPEQWKDGPKDTSVEDALERTYVPSLKTFQEEIMEKTGIAENRRHRKSYWY
What are the official names of this protein?
Probable 39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CSL3_ONCKE
Sequence: AISITCEGSDALLQCDGAKIHIKRANYGRRQHDVCSIGRPDNQLTDTNCLSQSSTSKMAERCGGKSECIVPASNFVFGDPCVGTYKYLDTKYSCVQQQETISSIICEGSDSQLLCDRGEIRIQRANYGRRQHDVCSIGRPHQQLKNTNCLSQSTTSKMAERCDGKRQCIVSVSNSVFGDPCVGTYKYLDVAYTCD
What is the function of this protein?
L-rhamnose binding lectin.  Has hemagglutinating activity towards rabbit erythrocytes, human type A erythrocytes, human type B erythrocytes, human type O erythrocytes and sheep erythrocytes.  Hemagglutinating activity is inhibited by smooth-type lipopolysaccharide (LPS) from S. flexneri 1A, A. salmonicida and E. coli K12, but not by rough-type LPS from S. flexneri, E. coli K12 and E. coli EH100.  Agglutinates E. coli K12 and B. subtilis.
What are the official names of this protein?
L-rhamnose-binding lectin CSL3.
Protein: KCY_BACC1
Sequence: MDKRISIAIDGPAAAGKSTVAKVVAKKLSYVYIDTGAMYRTITYAALEQKVDIENEEQLMEVVKNVKIEFQQGENTQLVFLNGQDVSEVIRTPEVTNRVSIVAKHRLVREEMVRRQQELAEKGGVVMDGRDIGTHVLPDAEVKIFMLASVEERAERRHLENMNKGFDSNLEQLKEEIAQRDKLDSEREVSPLKKADDALELDTTSLSIEEVVQKIMSIVSGVFAK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_ECOUT
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CTSR_STAA3
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: Y789_RICPR
Sequence: MSLKSTTSSLTTNNHDKTINSVQSLVNGTGTVADHNPYDEVPYESYPYAITNPYHLSTLATLFGINAPEVENSKILELGCAAGGNLIPHAVLYPNAHFVGVDLSKVQIDEANKNVRALGLKNIEFHHCSITDIDDSFGKFDYIICHGVISWVPKIVRDKIFKVCNRNLSTNGIAYISYNTLPGWNMVRTIRDMMLYHSSSFTNIRDRIAQSRLLLEFVKDSLEHSKTPYAEVLKTEAGLLAKQTDHYLRHDHLEEENAQFYFHEFMNEARKHNLQYLADCNISTMYLGNMPPKVVEQLKAVNDIVRTEQYMDFITNRRFRTTLLCHNDLKINRNINNDDIKKFNIIFNVIPEKPLKEVDLNNATENLQFFLNGNKESNLSTTSPYMKAILYTFSENLNNPLSFKQVTSEANTKLNNTKLNEIKNELLNNAMKLVLQGYISITNQKHRSKPVLDKPKTTQMVIYQAKYTPSMWVTNLKHEPIGVNFFEKFALRYMDGRNDKKAIIEAILGHVEKGELTLSREGQKIENKEEIRKELESLFTPMIEKFCSNALLV
What are the official names of this protein?
Uncharacterized protein RP789.
Protein: PRVB3_MERBI
Sequence: AFSGILADADIAAALKACEAADSFNYKAFFAKVGLSAKSAEDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDEFAVLVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 3.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: C5502_GLOVI
Sequence: MFSRQFGRLATLALALAVAGCAGGEQSTTAEAPSEPAPVAKPDVVSAATGELSNFSTADLKQAKKLFQAECGRCHVGGQTYGTYNSTDVSLSYDALTNATPPRNTVAGLVDYMKKPTSYDGRTDLLKTGEHASFTGLGDEKLRLIAGHIIKEATSNPNWGQGKDTR
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550 2, Cytochrome c550 2, Low-potential cytochrome c 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side. Note=Associated with photosystem II at the periplasmic side of the inner membrane.
Protein: KCRB_BOVIN
Sequence: MPFSNSHNTLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGHPYIMTVGCVAGDEESYDVFKELFDPIIEDRHGGYKPTDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCNGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.  Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.  During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work.
What are the official names of this protein?
Creatine kinase B-type, B-CK, Creatine kinase B chain, Creatine phosphokinase M-type, CPK-B.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Note=Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region.