PharMolix/UniProtQA huggingface dataset:
Protein: CATA_LISMO
Sequence: MTDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAGAHGKFVTKKSMKKYTMAKFLQEEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGNRYWDFFSLTPEATTMIMYLFSDEGTPASYREVRGSSVHAFKWINEEGKTVYVKLRWVPKAGIVNLSTEQASQIQAKEFNHASRDLYEAIENGDYPEWDLYVQVLDPKDLDSFDFNPLDATKDWFEDVFPYEHVGTMTLDRNPDNIFAETESVGFNPGVLVRGMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKAPVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEPEQEIRGDISGRLIAEKPNNFGHAKEVWDRYSNAERAALVKNIVDDWSQVREDIKIRNLRNFYQVDPEFASRVAAGTGINLEEHVTDLK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SYNR3
Sequence: MIKLRLKRFGKKRETSFRIVACNSTSRRDGRPLQELGFYNPRTKETRLDTDALRARLEQGAQPSDTVRTLLERGGLLTKSVRPAEVIGKLKQEEARKKEAADAKAAAKAEAEAKASEAAAAAAAAEEAPAEEAPAEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: AGUA_PSEA8
Sequence: MSNPTSTPRADGFRMPAEWEPHEQTWMVWPERPDNWRNGGKPAQAAFAAVAKAIARFEPVTVCASAGQYENARARLDDGNIRVVEISSDDAWVRDTGPTFVIDDKGDVRGVDWGFNAWGGFEGGLYFPWQRDDQVARKILEIERRARYRTDDFVLEGGSIHVDGEGTLITTEECLLNHNRNPHLSQAEIERTLRDYLAVESIIWLPNGLYNDETDGHVDNFCCYVRPGEVLLAWTDDQDDPNYLRCQAALRVLEESRDAKGRKLVVHKMPIPGPLYATQEECDGVDIVEGSQPRDPSIRLAGSYVNFLIVNGGIIAPSFDDPKDAEARAILQRVFPEHEVVMVPGREILLGGGNIHCITQQQPAPRKA
What is the function of this protein?
Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
What are the official names of this protein?
Agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: RPOZ_ACIF2
Sequence: MARVTVEDCLEHVDNRFELTLVAARRARQLASGAAPEVEPGRDKNTVIALREVAAGKVSRAILDEQMPPPLPNFPGAANREATGAEDAAGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IDGF4_GLOMM
Sequence: MKLLLILLGALLAVLTIKRTSAVQGSNHLICYYDGTSYTREGLAKLTLNDLEPALQFCTHLVYGHAAINPSSNKLVSNNEKLDLDVGTGLYRTITGMKKKYPHLKVLLSVGGDKDEVDADNNKYLTLLESSNARIPFINSAHSMVKTYGFDGLELGWQFPKNKPKKVHGSIGKLWKGFKKIFTGDFIVDEKAEEHKEEFTALVRELKNALRPDGYILGLAVLPNVNSSLFYDVPAIVNNLDYVNLMAYDFQTPQRNPEMADFPAPIYELNERNPESNVNYQVQYWLQNHCPASKINVGIPSYGRAWKMTTDSGLTGLPPVSDADGPAAGGLQTQTEGLLSWPEVCAKLPNPANQHLKGADSPLRKVGDPTKRFGNYAYRSTDDKGENGIWVSYEDPDTAANKAAYVKTKGLGGVALVDLSFDDFRGACTGDKYPILRAIKFKFQ
What is the function of this protein?
Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells.  May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity).
What are the official names of this protein?
Chitinase-like protein Idgf4, Imaginal disk growth factor protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. IDGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHS1_PHYB8
Sequence: MNPGQKQEHDQYPLHDTQFVPQQMDRNSPFADPYPEDQPPPSGYDHQPLLRDNAPSYPPDPFGQPGGYPPQSTMYPPQPMGPPSPNMRYGEAPRRQPRRYKTTRRVKLTHGNLILDCPVPTPYLQAVPIKDTKEFTHMRYTAATCDPADFASQGYTLRQPILQRNTELFIVLTMYNEDEILFARTMHGVMKNIAHLCSRVRSNVWEGPKAWEKVVVCIVSDGRKKIHPRTLSLLATLGVYQDGVAKNVVGDKPVTAHIYEYTTQLSVDPEMKFKGADKGMPPCQILFCLKENNQKKINSHRWFFQAFGPVINPNVCVLIDVGTRPGKTSIYHLWKAFDISSNIAGACGEIRAMSGTAGVALLNPLVAAQNFEYKMSNILDKPLESVFGYISVLPGAFSAYRFTALQNDENGHGPLEKYFLGESQHGADADIFTANMYLAEDRILCYELVAKKKANWVLHYVSSSYGETDVPDSVPEFISQRRRWLNGSFFAGCYALFHWRKVWASDHSFVRKLMFMFEDLYNTYNLIFSWFALGNFYLTFYILTSALGAESLDPKPFSANVASILHTILNYIYILLIIVQFILALGNRPQGSKWAYFGSMTFFAILMVYMMFATIWITVVGVQDAVANADGSFTAMLGESTFRNIIISIVSTYAMYFIASFLFFDPWHMFTSFIQYIFLSPSYTNILNIYAFCNTHDVSWGTKGDNTVSTDLGVVKSKKDGSGDTTVEVEVPTEQKDINEAYEEACVELTRQVEPEVSHRDAKTKQEDYYRSFRTRLVISWIISNLILVVLITNENILASFGTFEVRSTSYLGFVLWSVAGLSAIRFCGSGLYLIFRIFMG
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1, Class-II chitin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_SULSY
Sequence: MLASKFFMPTLKENPSDAVVPSHIYLVRGGFIRSLSAGIYEYLPLGLKVLRKIENIIRKHMDDSGALEVLLPILTPAELWKETGRWHVYGKELFRLKDRKDAEFALGPTHEETITDLVRKNVRSYKDLPLNFYQIQTKFRDEARPRYGLIRGREFIMKDGYSFDVSEEDAKKTYEVMKEAYHKIFKELGLDYLMVEADVGAIGGKFSHEFVVKVPSGEAHIVYCEKCGYAANVEAAKFHHHKLPPEEPKPIEKVYTPDIKSVEDVANFLNVPLTKLVKTLIYKIDDKDFVAVLIRGDRELNETKLANLFKAIDVRMATKEELESLGIPEGFVGPIGLNLPIYADFSLKELYNIVVGANEKDYHYINANIDRDFKVSGFYDLATAKEGDPCPVCHLPLKETTGLEVGHIFLLGTKYSESMKAYFVDKDGKEKSIIMGCYGIGVSRLISAIVEQYHDDKGIIWPENLAPFNVHILVLNPKDQESLNVGFDIYKKLKEKGLDVLLDERDESAGAKFKDADLIGIPHRIVIGKALKEGKVEYQKRDGSIKELVDVKLIINKLMDGYHG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TET2_MOUSE
Sequence: MEQDRTTHAEGTRLSPFLIAPPSPISHTEPLAVKLQNGSPLAERPHPEVNGDTKWQSSQSCYGISHMKGSQSSHESPHEDRGYSRCLQNGGIKRTVSEPSLSGLHPNKILKLDQKAKGESNIFEESQERNHGKSSRQPNVSGLSDNGEPVTSTTQESSGADAFPTRNYNGVEIQVLNEQEGEKGRSVTLLKNKIVLMPNGATVSAHSEENTRGELLEKTQCYPDCVSIAVQSTASHVNTPSSQAAIELSHEIPQPSLTSAQINFSQTSSLQLPPEPAAMVTKACDADNASKPAIVPGTCPFQKAEHQQKSALDIGPSRAENKTIQGSMELFAEEYYPSSDRNLQASHGSSEQYSKQKETNGAYFRQSSKFPKDSISPTTVTPPSQSLLAPRLVLQPPLEGKGALNDVALEEHHDYPNRSNRTLLREGKIDHQPKTSSSQSLNPSVHTPNPPLMLPEQHQNDCGSPSPEKSRKMSEYLMYYLPNHGHSGGLQEHSQYLMGHREQEIPKDANGKQTQGSVQAAPGWIELKAPNLHEALHQTKRKDISLHSVLHSQTGPVNQMSSKQSTGNVNMPGGFQRLPYLQKTAQPEQKAQMYQVQVNQGPSPGMGDQHLQFQKALYQECIPRTDPSSEAHPQAPSVPQYHFQQRVNPSSDKHLSQQATETQRLSGFLQHTPQTQASQTPASQNSNFPQICQQQQQQQLQRKNKEQMPQTFSHLQGSNDKQREGSCFGQIKVEESFCVGNQYSKSSNFQTHNNTQGGLEQVQNINKNFPYSKILTPNSSNLQILPSNDTHPACEREQALHPVGSKTSNLQNMQYFPNNVTPNQDVHRCFQEQAQKPQQASSLQGLKDRSQGESPAPPAEAAQQRYLVHNEAKALPVPEQGGSQTQTPPQKDTQKHAALRWLLLQKQEQQQTQQSQPGHNQMLRPIKTEPVSKPSSYRYPLSPPQENMSSRIKQEISSPSRDNGQPKSIIETMEQHLKQFQLKSLCDYKALTLKSQKHVKVPTDIQAAESENHARAAEPQATKSTDCSVLDDVSESDTPGEQSQNGKCEGCNPDKDEAPYYTHLGAGPDVAAIRTLMEERYGEKGKAIRIEKVIYTGKEGKSSQGCPIAKWVYRRSSEEEKLLCLVRVRPNHTCETAVMVIAIMLWDGIPKLLASELYSELTDILGKCGICTNRRCSQNETRNCCCQGENPETCGASFSFGCSWSMYYNGCKFARSKKPRKFRLHGAEPKEEERLGSHLQNLATVIAPIYKKLAPDAYNNQVEFEHQAPDCCLGLKEGRPFSGVTACLDFSAHSHRDQQNMPNGSTVVVTLNREDNREVGAKPEDEQFHVLPMYIIAPEDEFGSTEGQEKKIRMGSIEVLQSFRRRRVIRIGELPKSCKKKAEPKKAKTKKAARKRSSLENCSSRTEKGKSSSHTKLMENASHMKQMTAQPQLSGPVIRQPPTLQRHLQQGQRPQQPQPPQPQPQTTPQPQPQPQHIMPGNSQSVGSHCSGSTSVYTRQPTPHSPYPSSAHTSDIYGDTNHVNFYPTSSHASGSYLNPSNYMNPYLGLLNQNNQYAPFPYNGSVPVDNGSPFLGSYSPQAQSRDLHRYPNQDHLTNQNLPPIHTLHQQTFGDSPSKYLSYGNQNMQRDAFTTNSTLKPNVHHLATFSPYPTPKMDSHFMGAASRSPYSHPHTDYKTSEHHLPSHTIYSYTAAASGSSSSHAFHNKENDNIANGLSRVLPGFNHDRTASAQELLYSLTGSSQEKQPEVSGQDAAAVQEIEYWSDSEHNFQDPCIGGVAIAPTHGSILIECAKCEVHATTKVNDPDRNHPTRISLVLYRHKNLFLPKHCLALWEAKMAEKARKEEECGKNGSDHVSQKNHGKQEKREPTGPQEPSYLRFIQSLAENTGSVTTDSTVTTSPYAFTQVTGPYNTFV
What is the function of this protein?
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation.  Has a preference for 5-hydroxymethylcytosine in CpG motifs.  Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC).  Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation.  Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation.  In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
What are the official names of this protein?
Methylcytosine dioxygenase TET2, Protein Ayu17-449.
What is the protein family that this protein belongs to?
Belongs to the TET family.
Protein: RL27_MYCAP
Sequence: MAHTKAGGSTRNGRDSRGQRLGIKLGDGQFCTAGSIIFRQRGTKIFPGVNAGRGNDDTIYALITGYVKFERRRNRVYASVYPTRVQNSTSAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: JM706_ORYSJ
Sequence: MQQVEGRNCLPAEVRIGLETLKRRRLERMRLTAQNNAGDGPPVPARSGGDALRTPANCGVRLHANNGTALPSRTTQNKDPFAKRRVDKFDMSSLEWIDKIEECPVYYPTKEEFEDPIGYIQKIAPVASKYGICKIVSPVSASVPAGVVLMKEQPGFKFMTRVQPLRLAKWAEDDTVTFFMSERKYTFRDYEKMANKVFAKKYSSASCLPAKYVEEEFWREIAFGKMDFVEYACDVDGSAFSSSPHDQLGKSNWNLKNFSRLSNSVLRLLQTPIPGVTDPMLYIGMLFSMFAWHVEDHYLYSINYHHCGAFKTWYGIPGDAAPGFEKVASQFVYNKDILVGEGEDAAFDVLLGKTTMFPPNVLLDHNVPVYKAVQKPGEFVITFPRSYHAGFSHGFNCGEAVNFAISDWFPLGSVASRRYALLNRTPLLAHEELLCRSAVLLSHKLLNSDPKSLNKSEHPHSQRCLKSCFVQLMRFQRNTRGLLAKMGSQIHYKPKTYPNLSCSMCRRDCYITHVLCGCNFDPVCLHHEQELRSCPCKSNQVVYVREDIQELEALSRKFEKDICLDKEISGFDSYKQAEKNEPFFEITRNLRNTEVNLIEDAFSGATAADAAKSSPATSTLTSFAQHDVPVLAEAIVCANQADQLYSTTEQTISSPLVKGTDAVGANSSSMADANNGTGSCNASAVEYSGNSDSESEIFRVKRRSGVSVKPASDAKTSNLSDQQVLRRLKKVRPEIQQHNKRPEDYGHCSVPSGRMSMKNLNSSSSCGEEHWRMKRRQLETQQDESSYSAKQKSYSYPSTSYSFRGEFVEMSRDAAAEVRPKRLKIRLPSSSTNRVVEQGSSGQRFTRDDKSLGCWPAI
What is the function of this protein?
Histone demethylase that demethylates 'Lys-9' (H3K9me) of histone H3 with a specific activity for H3K9me3 and H3K9me2.  No activity on H3K4me3, H3K9me1, H3K27me2 and H3K36me3/2.  Involved in the control of floral organ development by demethylating H3K9me3 and H3K9me2 in the promoter regions of DH1 and MADS47.  The 'Lys-9' demethylation of these two genes is required for induction of their expression.
What are the official names of this protein?
Lysine-specific demethylase JMJ706, Jumonji domain-containing protein 706, Lysine-specific histone demethylase JMJ706, Protein JUMONJI 706, [histone H3]-trimethyl-L-lysine(9) demethylase JMJ706.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes mainly in heterochromatin foci.
Protein: NUOB1_HERA2
Sequence: MGLEEKAGDLGIVTTTLEGVVNWGRTKAMWPMLFGLACCAIEMMAGQASNYDMSRFGLELMRASPRQADLMIVAGRVSRKMAPVLRRLYDQMPEPKWVVAMGDCASCGGVYNNYAIVQGVDEIVPVDVYVAGCPPRPEALIDGILQLHEKIKRDKITDHADGKPIRIEQAERGALKPLG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CMR_MYCTU
Sequence: MADRSVRPLRHLVHAVTGGQPPSEAQVRQAAWIARCVGRGGSAPLHRDDVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAVVNILHPGDVDGDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRVSTAQIRLMGMLGRPLPAQVAQLLLDEAIDARIELAQRTLAAMLGAQRPSINKILKEFERDRLITVGYAVIEITDQHGLRARAQ
What is the function of this protein?
Positively regulates the expression of at least groEL2.  Cyclic AMP does not affect transcription in vitro.
What are the official names of this protein?
HTH-type transcriptional regulator Cmr.
Protein: SSPC_STAAW
Sequence: MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRHGDDTSHNQYHILFIDTAHQRIKFSSIDNEEIIYILDYDDTQHILMQTSSKQGIGTSRPIVYERLV
What is the function of this protein?
Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme.  Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B.  Also involved in growth capacity, viability and bacterial morphology (By similarity).
What are the official names of this protein?
Staphostatin B, Staphylococcal cysteine protease B inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I57 (SspC) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_HYPNA
Sequence: MDSATGALALEDGTIFAGFGAGAAGIKVGELCFNTAITGYQEILTDPSYASQLVLFTFPHIGNVGANAEDHEESTVEAADAARGAIFREPITAPSNWRSTEDFGVWLARRGIIGLSGIDTRALTKRIREKGMPKAAICHKPDGKIDFDALVELARSWNGLDGADLADVVDQDAPFEHTEGLWQAATGHQTALANAEFHVAVIDFGVKKNILRNLASAGARATVVNGNVSAEEVLALKPDGIVFANGPGDPAATFERSGEMIKTLVASGLPILGICLGHQLLGLALGAKTKKMAQGHHGANHPVKDLATGKVEIVSMNHGFTVDPDTLPPGVEESHRSLFDGTNSGLAVKGKPIISVQHHPEASPGPQDSFYLFTRFAGLMRDYRAK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: EFTU_CHLPM
Sequence: MAKESYKRDKPHVNIGTIGHVDHGKTTLTAAITSVLAKSGMADAREFGDIDKAPEERERGITISTAHVEYQTVKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVFLNKVDIADPELLELVEMELRELLTEYGFPGDDIPIIKGSALKALDGDAEGEKAIMELMDAVDNYIPEPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGRIKINEEVEIVGIRDTRKSVVTGIEMFQKLLDEGQAGDNAGLLLRGVDKNDLERGMVIAKPGTIKPHTKFKAEVYILKKEEGGRHTPFFTNYRPQFYFRTTDVTGAVSLPEGVEMVMPGDNLSVEVELIAPIAMDEGLRFAIREGGRTVGAGSVTKIND
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROGDI_MOUSE
Sequence: MATAMAASAAERAVLEEEFRWLLHAEVHAVLRQLQDILKEASLRFTLPGPSTEGPAKQENFILGSCGTDQVKGTLTLQGDALSQADVNLKMPRNNQLLHLAFREDKQWKLQQIQDARNHVSQAIYLLANRDESYQFKTGAEVLKLMDAVMLQLTRARSRLTTPATLTLPEIAASGLTRMFAPTLPSDLLVNVYINLNKLCLTVYQLHALQPTSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQLCQQLKDKIAVFSSYWSSRPF
What are the official names of this protein?
Protein rogdi homolog, Leucine-zipper-containing LZF.
What is the protein family that this protein belongs to?
Belongs to the rogdi family.
What are the subcellular locations of this protein?
Nucleus envelope. Presynapse. Cell projection, axon. Perikaryon. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Detected primarily at presynaptic sites on axons, and to a lesser degree in soma and dendrites. Not detected at post-synaptic sites.
Protein: DXS_SYNS3
Sequence: MHLSELTHPNQLHGLSETQLEAVAKQIRERHLEVVSNSGGHLGPGLGVVELTLALYQTLDLDRDKVVWDVGHQAYPHKLITGRYGSFDSLRQQGGVAGYLKRTESRFDHFGAGHASTSISAALGMAIARDRQGLDYKCVAVIGDGALTGGMALEAINHAGHLPSTPLLVVLNDNDMSISPPVGALSTYLNRMRLSPPLQFLSGSVEESVRNLPFMGGEIPPELNRLKESMRRLAVPKVGAVFEELGFTYMGPIDGHDIAEMTRTFQSAHRVGGPVMVHVVTKKGKGYPYAEADQVGYHAQSAFNLSTGKARPSKTPKPPSYSKVFGQTLVKLCEQNPKVVGITAAMATGTGLDILQKALPDQYIDVGIAEQHAVTLSAGMACDGLRPVVAIYSTFLQRAFDQLIHDVGIQKLPVTFVLDRAGIVGADGPTHQGQYDISYMRAIPNFTVMAPKDEAELQRMLVTCLNHDGPTALRIPRGPGEGVPLMEEGWEALPIGCGEVVREGNDVLIVAYGAMVPKAMATAKCLAAVGVEVAVINARYLRPLDEALIHPMAKQIGKIVTMEEGALAGGFGSAVLESLQEKGLAIPMLRIGIPDRLVDHATPQQSFEALGLTPDQMAVRIKQHFLLSTSGSLTLEEKAPAEVSSAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: I6_FOWPN
Sequence: MDNFLKQISSNVKKPIAELEDPDAVIKFHYMNISFNFPDLYYCNNNLFDKPENNLLDISKSLLMLNSFSHECFILQDILRVIRRYGHVYDVYFLPIGWLVGHGEAPKYHASIKLIRSNTQEIIDGIIRRQLSQYGIQGDNLSIFVDSSNEVAINRHSIIGARQLNPICVVSFYPFDPEHKVFFVIYVGRYKDKYCGISYVADREDMYKVINRIYPYVSCFYLVSDGIINFHTTPVANHTRNIKPLPVNYCNTLCEIVYDFEYLKFEQGVMSIPVFMPFVPKQFVSIINLPDDILITCTASSNIEYITHIDNKKLKRILIIIKDKFLKGTIMQGTFKKVNIIRHKKYTYTITYSSFDCPKLEDTKSSLPSTCNKAILDGRRYVTKTFNDTI
What is the function of this protein?
Binds to the hairpin form of the viral telomeric sequence.  Might direct genome encapsidation into the virus particle (By similarity).
What are the official names of this protein?
Telomere-binding protein I6 homolog, Protein FPV084.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae I6 family.
What are the subcellular locations of this protein?
Virion. Note=Present in the virus core.
Protein: SYGB_PSEAB
Sequence: MSAKDFLVELGTEELPPKALNSLGEAFLSGIEKGLKAAGLSYAAARFYAAPRRLAVLVEQLAVQQPDRTVNLDGPPLQAAFDASGNPTQAALGFAKKCGVDLQQIDKSGPKLRFSQTIAGQPAAGLLPGIVEASLNELPIPKRMRWAARREEFVRPTQWLVMLFGDDVVECEILAQKAGRESRGHRFHNPDNVRISSPAAYLEDLRGAHVLADFAERRELIAKRVAELAAEQQGSAIVPPSLLDEVTALVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDANGKLLPRFITVANVESKAPENIVSGNEKVVRPRLTDAEFFFKQDKKQPLESFNERLRNVVFQAQLGTVFEKAQRVSGLAAYIAERIGGNAQNAARAGILSKCDLATEMVGEFPEMQGIAGYYYATHGGEAEDVALALNEQYMPRGAGAELPSTLTGAAVAVADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLVAAVNAAVEQYGDKVKAAGLAEQVLDFVFDRLRARYEDEGVDVAVYQSVRALKPSSPLDFDQRVQAVQAFRQLPEAEALAAANKRVSNILAKSEDEVPPNVDASLLVEAAEKALGSAVANAESEVAPLAAARDYRAALARLAALREPVDTFFADVMVNVDDAAVRANRYALLAKLRGSFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFC1_BACC1
Sequence: MKKKIGLLVMAYGTPYKEEDIERYYTHIRRGRKPSPEMLEDLTERYRAIGGISPLATITLEQAKKLEKRLNEVQDEVEYHMYLGLKHIEPFIEDAVKDMHNDGIQDAIALVLAPHYSTFSVKSYVGRAQEEAEKLGNLTIHGIDSWYKEPKFIQYWVDAVKGIYNGMSDAEREKAVLIVSAHSLPEKIIAMGDPYPEQLHETADYIARGAEVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEKHGYTSFVYAPVGFVAEHLEVLYDNDFECKVVTDEIGAKYYRPEMPNASDAFIDCLTDVVLKKKESVL
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase 1.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_HV192
Sequence: MEQAPEDQGPQREPYNEWTLELLEELKREAVRHFPRPWLHGLGQHIYETYGDTWTGVEAIIRILQRLLFVHFRIGCQHSRIGILRQRRARNGASRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: TPM1_HUMAN
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells (PubMed:23170982).  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982).  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: TRMB_LACJO
Sequence: MRLRNKPWAQKLVAEHPEVILNEPDPDKKINWEERFEDFSKPLAIEIGSGKGQFITTLAKEHPEMNFIGVELQTTAAGMILRTKLEEKIDNLQLMCADAANIAMYLPENSVDIVYLNFSDPWPKTRHEKRRLTYKSFLDKYRQILKPEGHLEFKTDNRGLFEYSLVSLNNYGMKFDYVSLDLHHADDEIFERNVETEYEHKFAAKGNPIYCLHAHFVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: METN_HELAH
Sequence: MVVELKNIEKIYENGFHALKGVDLELKKGDILGVIGYSGAGKSTLIRLINCLERPSSGEVLVNGVNLLQLKPKELQKARQKIGMIFQHFNLLSAKNVFENVAFALEIAQWEKNKIKSRVHELLELVGLEDKMHFYPKQLSGGQKQRVAIARSLANYPNLLLCDEATSALDSKTTHSILTLLRDIQKKLDLSVVFITHEIEVVKELCNQMCVISNGKIVERGLVEEIFANPKHAVTKELIGIKNEHADKKSQNVYRIVFLGEHLDEPIISNLIRRFKIDVSIISGNIEELTTKDIGYLVVRFLGSIAETQRALEYLNALGLQVEKLKD
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.