PharMolix/UniProtQA huggingface dataset:
Protein: ABF1_YEAST
Sequence: MDKLVVNYYEYKHPIINKDLAIGAHGGKKFPTLGAWYDVINEYEFQTRCPIILKNSHRNKHFTFACHLKNCPFKVLLSYAGNAASSETSSPSANNNTNPPGTPDHIHHHSNNMNNEDNDNNNGSNNKVSNDSKLDFVTDDLEYHLANTHPDDTNDKVESRSNEVNGNNDDDADANNIFKQQGVTIKNDTEDDSINKASIDRGLDDESGPTHGNDSGNHRHNEEDDVHTQMTKNYSDVVNDEDINVAIANAVANVDSQSNNKHDGKDDDATNNNDGQDNNTNNDHNNNSNINNNNVGSHGISSHSPSSIRDTSMNLDVFNSATDDIPGPFVVTKIEPYHSHPLEDNLSLGKFILTKIPKILQNDLKFDQILESSYNNSNHTVSKFKVSHYVEESGLLDILMQRYGLTAEDFEKRLLSQIARRITTYKARFVLKKKKMGEYNDLQPSSSSNNNNNNDGELSGTNLRSNSIDYAKHQEISSAGTSSNTTKNVNNNKNDSNDDNNGNNNNDASNLMESVLDKTSSHRYQPKKMPSVNKWSKPDQITHSDVSMVGLDESNDGGNENVHPTLAEVDAQEARETAQLAIDKINSYKRSIDDKNGDGHNNSSRNVVDENLINDMDSEDAHKSKRQHLSDITLEERNEDDKLPHEVAEQLRLLSSHLKEVENLHQNNDDDVDDVMVDVDVESQYNKNTTHHNNHHSQPHHDEEDVAGLIGKADDEEDLSDENIQPELRGQ
What is the function of this protein?
General regulatory factor (GRF) that contributes to transcriptional activation of a large number of genes, as well as to DNA replication, silencing and telomere structure.  Involved in the transcription activation of a subset of ribosomal protein genes.  Binds the ARS-elements found in many promoters.  Binds to the sequence 5'-TCN(7)ACG-3'.  Influences on genome-wide nucleosome occupancy and affects chromatin structure, and probably dynamics.  As a component of the global genome repair (GGR) complex, promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA.  Component of the regulatory network controlling mitotic and meiotic cell cycle progression.
What are the official names of this protein?
ARS-binding factor 1, Bidirectionally acting factor 1, DNA replication enhancer-binding protein OBF1, SFB-B.
What is the protein family that this protein belongs to?
Belongs to the BAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_ECOLC
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKI7_YEAST
Sequence: MSLLEQLARKRIEKSKGLLSADQSHSTSKSASLLERLHKNRETKDNNAETKRKDLKTLLAKDKVKRSDFTPNQHSVSLSLKLSALKKSNSDLEKQGKSVTLDSKENELPTKRKSPDDKLNLEESWKAIKEMNHYCFLKNDPCINQTDDFAFTNFIIKDKKNSLSTSIPLSSQNSSFLSLKKHNNELLGIFVPCNLPKTTRKVAIENFNRPSPDDIIQSAQLNAFNEKLENLNIKSVPKAEKKEPINLQTPPTESIDIHSFIATHPLNLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSFKVILDNTKTERENGFSMFKKVIQVENDLLPPSSTLTLIDTPGSIKYFNKETLNSILTFDPEVYVLVIDCNYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKADLISWDKHRLEMIQSELNYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEFDSINYVPEWYEGPTFFSQLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLKVLINSGYIQSGQTIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEVLVKIHNTEDFTKKQFHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLIKLSIQTHALSDPVDLGSELLLYHNLTHNAVKLVKILGTNDISINPNQSLIVEVEIIEPDFALNVIDSKYITNNIVLTSIDHKVIAVGRIACQ
What is the function of this protein?
Represses the expression of non-poly(A) mRNAs like L-A or M viruses and is therefore involved in antiviral system.  Mediates interactions via its N-terminus between the exosome and the SKI complex which operate in the 3'-to-5' mRNA-decay pathway.  By interacting with NAM7, is also required for nonsense-mediated 3'-to-5' mRNA-decay (NMD).  May recognize a stalled 80S ribosome at the 3'-end of a nonstop mRNA which leads to the recruitment of the exosome and SKI complexes to the mRNAs to be degraded.
What are the official names of this protein?
Superkiller protein 7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RING1_PANPA
Sequence: MDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGGGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
What is the function of this protein?
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation.  H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.  Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.  Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RING1, Polycomb complex protein RING1, RING finger protein 1, RING-type E3 ubiquitin transferase RING1.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: Y1154_METTH
Sequence: MIEMYRKILVPTMGEYMDELIEHTLDLLHGREAEVICLYVVDTAVPFLTPKKVKEMMVKELTQRGNEILRDMEKGLTGPENPNVSFRAVMREGDPADEIVKVAEEEDVDVIVMGTGKSLVDKHLLGSVSEKVVHYAPCTIHLVRTV
What are the official names of this protein?
Universal stress protein MTH_1154, USP MTH_1154.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: ASTB_SERP5
Sequence: MSGYEVNFDGLVGLTHHYAGLSFGNEASTQHQNSVSNPKLAAKQGLLKMKALADLGFQQGVLPPQERPHVPMLRKLGFSGSDESVLAQAMQQSPRLLSALSSASCMWTANAATVSPSADSADGKVHFTAANLNNKFHRAIEAETTSGVLRAMFNDPRHFAHHEALPQVALFGDEGAANHNRLGGDYGKRSVQMFVYGRQEFGGEIAPTRYPARQTREAGEAIARLHQLDEQHTVFVQQNPEVIDQGVFHNDVIAVSNQNVLFHHQQAFYRQQQALDEVRRKMATLDSELVAIEVPTTRVSVADAVATYLFNSQILTKPNGKMMIVVPEESRQHSGVWSYLSEMVASGGPIDEIKVFDLRESMRNGGGPACLRLRVALNEQELRAVNPRVMMNDSLFITLNEWVDRYYRDRLTQNDLADPQLLREGREALDSLTTILGLGSVYPFQQ
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: THCD_RHOER
Sequence: MSIVIIGSGQAGFEAAVSLRSHGFSGTITLVGDEPGVPYQRPPLSKAYLHSDPDRESLALRPAQYFDDHRITLTCGKPVVRIDRDAQRVELIDATAIEYDHLILATGARNRLLPVPGANLPGVHYLRTAGEAESLTSSMASCSSLVVIGAGFIGLEVAAAARKKGLDVTVVEAMDRPMARALSSVMSGYFSTAHTEHGVHMRLSTGVKTINAADGRAAGVTTNSGDVIHADAVVVGIGVVPNIELAALTGLPVDNGIVVDEYLRTPDENISAIGDCAAYPIPGKAGLVRLESVQNAVDQARCLAAQLTGTSTHYRSVPWFWSEQYESKLQMAGLTAGADTHVVRGSVDSGVFSIFCFLGTRLLGVESVNKPRDHMAARKILATEMPLTPEQAADTDFDLKLAIARHKDTHKDEVASADIGERQVVAS
What is the function of this protein?
The degradation of the thiocarbamate herbicide EPTC by cytochrome CYP116 (thcB) requires the participation of a flavoprotein, rhodocoxin reductase, and an iron-sulfur protein, rhodocoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation.
What are the official names of this protein?
Rhodocoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
Protein: NAPA_BORBR
Sequence: MARRDFIKQTAAAAAATVAGVPLTGYTQNIVTESEAAKLKWSKAPCRFCGTGCGVNVAVKDNQVVATHGDFNAEVNKGLNCVKGYFLSKIMYGSDRLTQPLLRMKDGKYAKDGEFAPVSWDQAFDVMAEQFKRVLKDKGPEAVGMFGSGQWTVWEGYAALKLMKAGFRTNNLDPNARHCMASAAVGFMRTFGADEPMGCYDDIENADAFVLWGSNMAEMHPILWTRVTDRRLSAPATKVAVLSTFEHRSYELADLTLTFEPQSDLAILNYIANHIIRTKRVNRDFVDKHTVFREGNADIGYGLRPEHPLQQAARNAGDAGGSKPITFDDFARFVSKYDLEYTAKLSGVPKNRLEELAELYADPKVRVTSFWTMGFNQHTRGVWCNNMVYNIHLLTGKISTPGNSPFSLTGQPSACGTAREVGTFSHRLPADLVVTNPEHRRHAEEIWKLPDGTIPSKVGAHAVLQNRMLKDGKINAYWVMVNNNMQAAANLMNEGLPGYRNPENFIVVSDAYPTVTTLSADLILPAAMWVEKEGAYGNAERRTQFWHQLVDAPGQARSDLWQLVEFSKRFKVEEVWPADLLAKKPEYRGKTLYDVLFANGKVNQFPNTELDAEYANQEAQAFGFYLQKGLFEEYAEFGRGHGHDLAPFDVYHKARGLRWPVVDGKETLWRYREGSDPYVKPGTGFQFYGNPDGKAVIFALPYEPPPEAPDKEYPFWLSTGRVLEHWHSGSMTRRVPELYKAFPEAVCFMHPDDAQALGVRRGVEVEVVSRRGRMRTRVETRGRDKPPRGLVFVPWFDAGQLINKVTLDATDPISFQTDFKKCAVKIVKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLYA_SHESM
Sequence: MLKKDMNIADYDPELFNAIQNETLRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVETLAIERAKQLFGATYANVQPHSGSQANSAVYMALLKPGDTVLGMNLAHGGHLTHGSPVNFSGRLYNIIPYGIDESGKIDYDEMERLAVEHKPKMMIGGFSAYSGIVDWARMREIADKIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTSTTHKTLAGPRGGIILSAADDEDLYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKAYQQQVVKNAKAMVEVFLERGYKIVSGGTDNHLMLVDLIGRDLTGKEADAALGSANITVNKNSVPNDPRSPFVTSGVRIGTPAITRRGFKEAEAKELTGWICDILDDAHNPAVIERVKGQVLALCARFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_ADICA
Sequence: MTIRSPEPEVKIMVEKDPVKTSFEKWAQPGHFARNLAKGPSTTTWIWNLHADAHDFDSHTNDLEDISRKIFSAHFGQLAIIFIWLSGMYFHGARFSNYESWLNDPTHVKPSAQVVWPIVGQEILNGDVGGGFQGVQITSGFFQLWRASGITSELQLYCTAVGALVFAGLMFFAGWFHYHKAAPKLAWFQNVESMLNHHLAGLLGLGSLGWAGHQIHVSLPINQLLDAGVDPEEIPLPHELILNRDLLAQTYPSFAKGLIPFFTLNWSEYSDFLTFRGGLNPITGGLWLTDTAHHHLAIAVLFLVAGHMYRTNWGIGHSTKEILEAHKGPFTGEGHKGIYEILTSSWHAQLAINLATLGSLTIIVSHHMYAMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFVVRDYDPTTQYNNLLDRVIRHRDTIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHALAPGSTAPNATAGTSLAWGGSDLVAVAGKVALAPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGSVSEQGAVSHITGGNFAQSSTTINGWLRDFLWAQASQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPVTQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIVAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SIW14_YEAST
Sequence: MGLYQAKNDEGSDPKSSSKIDDLIENEAEIIRLIKEDGKLLIDNGDGRDIHNIIQEDKLLSVEFNEVLKRFHGEEKSDIPRKEFDEDEDDGYDSNEHHQKTIEVMNTLNHVINKEVIPPENFSHVVGEIYRSSFPRQENFSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQVGMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHCNRGKHRTGCLIGCIRKLQNWSLTMIFDEYRRFAFPKARALDQQFIEMYDDDEIKRIASKNNWLPLQW
What is the function of this protein?
Selectively cleaves the beta-phosphate at the 5-position of soluble inositol pyrophosphates.  Converts 5-diphosphoinositol tetrakisphosphate (5-PP-InsP(4)) into inositol pentakisphosphate (InsP(5)), 5-diphosphoinositol pentakisphosphate (5-PP-IP(5) or 5-InsP(7)) into inositol hexakisphosphate (IP(6) or InsP(6)), and 1,5-bisdiphosphoinositol tetrakisphosphate (1,5-PP-IP(5) or InsP(8)) into 1-diphosphoinositol pentakisphosphate (1-PP-IP(5) or 1-InsP(7)) (PubMed:26828065, PubMed:29540476).  Modulates inositol pyrophosphate metabolism that may have an influence in stress response (PubMed:26828065).  Plays a role in actin filament organization and endocytosis (PubMed:15020461).  Functions as a prion suppressing factor possibly due to its phosphatase activity against inositol pyrophosphates, which are signal transduction molecules involved in prion propagation (PubMed:28923943).
What are the official names of this protein?
Inositol phosphatase SIW14, 5-PP-InsP phosphatase, Inositol pyrophosphate phosphatase SIW14, Oxidant-induced cell-cycle arrest protein 3, Synthetic interaction with WHI2 protein 14.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_ANADF
Sequence: MRYHPHTPEDVRAMLDVIGAESLDDLFRSIPERLRLARPLDLPPAADEITLFAELRALAARDDTAHPPFVGAGCYPHHVPPAVDQLLLRGEFFTAYTPYQPEVSQGTLQALFEWQTFVCLLTGMDVSNASMYDGATAMAEAALMATRVTGRSKIVVSAAVHPEYRKVLATYLRSTGDEIVTVPFGADGRTDLRALEAAVDGGTAAVIVGYPSFLGVVDALPQAAAIAKKAGALTVAVTAEAVALGLLQAPGALGADVAVGTFQSFGNPMSFGGPAPGFFAIREQFVRQMPGRVCGATVDKHGRRGFVLTLSTREQHIRREKATSNICTNSGLAALAATIHLALLGKQGLAELARLNFARARMLKDALGRAGIAPLFSAPPFNELAFDVGDAEAVVARLAKRGIAAGAPLARWYPELPRAKGALLSVATELHTPELIELFAQSVKG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: LYTH_STAES
Sequence: MKKIDSWLTKHGLKNRLTLVVIVIFIIFLILLFMFVNLSDEDTGQITITENAELRTGPNAAYPVIYKIEKGESFKKIDRKGKWIEVQNHAGTEKGWVAGWHTNLNIPADQSLSSNPLKGKTIVLDPGHGGSDQGASSSTPSKSLEKNYTLKTAKELKKLLNKEGAHVKMTRSNDKYVSLDDRNIKGDAFISIHNDALDSSNANGVTVYWFKDKQESLAQTLNSAIQKKALLTNRGSRQQNYQVLRQTDIPAVLLELGYISNPTDESMINDQLHRQVVEQAIVDGLKQYFSS
What is the function of this protein?
Probably involved in cell-wall metabolism.
What are the official names of this protein?
Probable cell wall amidase LytH.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_FRACC
Sequence: MAATDVRPKITMACQVCKHRNYITRKNRRNDPDRLELKKFCPNCGKHTEHRETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: THIM_SALNS
Sequence: MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLALGASPAMVIDPVEARPFAAIANALLINVGTLTASRADAMRAAVESAYDAKTPWTLDPVAVGALEFRRRFCLDLLSLRPAAIRGNASEILALSGMALGGRGVDTTEAALAALPAAQALARQIDCIVVVTGEVDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAALDNVASACCWMKLAGQAAAERSEGPGSFIPAFLDALYHLDVEAANATN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: FTHS_AGRVS
Sequence: MSDIEIARAASKLAITQIGERLGISPGDLQPYGHDKAKISASFLHSLEDRKDGKLILVTAINPTPAGEGKTTTTVGLVDGLNRIGAKAMVCVREPSLGPCFGVKGGAAGGGRAQVVPMEDINLHFTGDFHAITSAHNLLAAMIDNHIYWGNEQDLDTRRIAWRRVVDMNDRALREMVGALGGVRNGFPRETGFDITVASEVMAILCLARDLADLEERLGQIVIGYRRDKTPVHARDIKAHQAMTVLLKEAMQPNLVQTLENNPALVHGGPFANIAHGCNSVVATRAALKLADYVVTEAGFGADLGAEKFFDIKCRKAGLRPAAAVIVATVRALKMNGGVAKTELGHEDVAALVRGAVNLGRHVENVRGFGVPVIVAINHFLSDTPAEIAALQDYAASIGVEAVLCRHWAEGGAGIEELARKVAAMADSGIADFQPLYPDDMPLFAKIETVAKRIYRAGSVTADRAVIDQLSQFEAMGYGDLPVCIAKTQYSFSTDPSLLGAPDGHEVHVRDVRLSAGAGFVVAITGDIMTMPGLPRKPAAETIRLDDDGLVEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CDHR1_MOUSE
Sequence: MRRGPRVALVLGLLRIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRGSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAATKFILKEDSPNENCNNSRVGVMVPPRAPALPPPPKMASSMVAQQTVPTVSGSLTPQPSPQLPTPKTLGGPVQSSLVSELKQKFEKKSLDNKAYI
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
What are the official names of this protein?
Cadherin-related family member 1, Photoreceptor cadherin, prCAD, Protocadherin-21.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region.
Protein: RL28_FUSNN
Sequence: MQRCEITGTGLISGNQISHSHRLTRRVWKPNLQVTTLVVNGSPIKVKVCARTLKTLKGASEVEVMRILKANIATLSERLLKHLNK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: XERC_MYCSS
Sequence: MESVLDAFDQYLALERGRSDHTRRAYLGDLRSLFAFCNERTPGADLGSLTLPVLRAWLSAQAAAGTARTTLARRTSAVKTFTAWAVRRGLMASDPATRLQMPKARRTLPAVLRQDQARDALDAANSGAQQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTSRRLLRVLGKGDKQRTVPFGEPAEQALRAWLTSGRPALATAESGPALLLGARGRRLDPRQARTVVHETVGAVAGAPDIGPHGLRHSAATHLLEGGADLRIVQELLGHSTLATTQLYTHVTVARLRAVHDQAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_SALPA
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GREA_TREPA
Sequence: MVSGRGLVVTAKMLNAKKKELQDLLDVRIPENSREIGRALELGDLRENAEYKAAREEQTRLNNMVTRLQEEIERAQVFDPTTVVAGRVSFGTVISLKNHTSGEDETYTILGPWESAPERGIISYMSPLGSNLLNRKTGEQLAFTVGEHEKVYEILSISAAEI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TYPH_VIBPA
Sequence: MYLPQEIIRKKRDGEVLTADEINFFIQGVANNTVSEGQIAAFAMTIFFNEMTMDERIALTCAMRDSGMVIDWSHMNFGGPIVDKHSTGGVGDVTSLMLGPMVAACGGFVPMISGRGLGHTGGTLDKLEAIPGYNITPTNEVFGQVTKDAGVAIIGQTGDLAPADKRVYATRDITATVDNISLITASILSKKLAAGLESLVMDVKVGSGAFMPTYEASEELAKSIVAVANGAGTKTTAILTDMNQVLASSAGNAVEVREAVRFLTGEYRNPRLLEVTMASCAEMLVLAKLAENTDDARAKLMEVLDNGKAAACFGKMVAGLGGPADFVENYDNYLEKAEIIKPVYATETGIVSAMDTRAIGMAVVSMGGGRRVATDEIDYAVGFDNFIRLGEVADSDKPLAVIHARSEGQWEEAAKALRSAIKVGGEYTPTPEVYRQIRAEDI
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: UBIA_SALAR
Sequence: MEWSLTQSKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGMPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTVNRPLPSGAVTEKEARNLFVVLVLLAFLLVMTLNVMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDIKIGIKSTAILFGRYDKLIIGILQLGVMALMALIGWLNGLGGGYYWAVLVAGALFAYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.