PharMolix/UniProtQA huggingface dataset:
Protein: LUXS_BACSU
Sequence: MPSVESFELDHNAVVAPYVRHCGVHKVGTDGVVNKFDIRFCQPNKQAMKPDTIHTLEHLLAFTIRSHAEKYDHFDIIDISPMGCQTGYYLVVSGEPTSAEIVDLLEDTMKEAVEITEIPAANEKQCGQAKLHDLEGAKRLMRFWLSQDKEELLKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: CLC1A_BOVIN
Sequence: MLAKYSSTRDMLDADGDTTMSLHSQASATSQRPELGHTEHQRPSSAWRPVALILLTLCLVLLIGLAALGLVFFQFYQLSNTQQDSILQKEEKLGNLSRQLQSLRTQNRKLAETLHHVAEKLCRELYNKTGEHRCSPCPEKWKWHGDKCYQFYKESKSWQGCEYFCIAENSTMLKINTQEVLEFAMPQSYSEFFYSYWTGLSRNSSGKAWLWMDGTPYSSELFDVMIDLTSLRSRDCVTILNGKAFSKDCRELRRCACEKAAAMVKVQSLHEPLSRRWR
What are the official names of this protein?
C-type lectin domain family 1 member A, C-type lectin-like receptor 1, CLEC-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: NCF2_HUMAN
Sequence: MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGKLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEHTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
What is the function of this protein?
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
What are the official names of this protein?
Neutrophil cytosol factor 2, NCF-2, 67 kDa neutrophil oxidase factor, NADPH oxidase activator 2, Neutrophil NADPH oxidase factor 2, p67-phox.
What is the protein family that this protein belongs to?
Belongs to the NCF2/NOXA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_THEYD
Sequence: MTNTQFYITNFLNHIKLQKGDSSHTLRAYKNDLEEFFNFAKVEPEKVEPIVIRGFISEQILKGKSKTTVARKLSTLRSFFSYLYSEGFIKINPARVVSSVKIKRALPKFLTVDDAFKLVEAPSEDKFTVQRDKAILELFYSSGIRVSELCGLNLEDLDLKEGLIKVRGKGKKERIVPVGQKAKEALKKYLAIRQILRIKKKLSLDETPLFINNRGQRISDRQVRRIVEKYAKFIGVLEKIGPHTLRHTFASHLLMEGADLRVIQELLGHASLSTTQIYTHVDLKHLIEVYDKSHPLSKEDE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_SCVLB
Sequence: MSSLLNSLLPEYFKPKTNLNINSSRVQYGFNARIDMQYEDDSGTRKGSRPNAFMSNTVAFIGNYEGIIVDDIPILDGLRADIFDTHGDLDMGLVEDALSKSTMIRRNVPTYTAYASELLYKRNLTSLFYNMLRLYYIKKWGSIKYEKDAIFYDNGHACLLNRQLFPKSRDASLESSLSLPEAEIAMLDPGLEFPEEDVPAILWHGRVSSRATCILGQACSEFAPLAPFSIAHYSPQLTRKLFVNAPAGIEPSSGRYTHEDVKDAITILVSANQAYTDFEAAYLMLAQTLVSPVPRTAEASAWFINAGMVNMPTLSCANGYYPALTNVNPYHRLDTWKDTLNHWVAYPDMLFYHSVAMIESCYVELGNVARVSDSDAINKYTFTELSVQGRPVMNRGIIVDLTLVAMRTGREISLPYPVSCGLTRTDALLQGTEIHVPVVVKDIDMPQYYNAIDKDVIEGQETVIKVKQLPPAMYPIYTYGINTTEFYSDHFEDQVQVEMAPIDNGKAVFNDARKFSKFMSIMRMMGNDVTATDLVTGRKVSNWADNSSGRFLYTDVKYEGQTAFLVDMDTVKARDHCWVSIVDPNGTMNLSYKMTNFRAAMFSRNKPLYMTGGSVRTIATGNYRDAAERLRAMDETLRLKPFKITEKLDFSCSSLRDTKFVGQQYAILTPSGTTTDIRSGRGTNQSYRRGRTSTGYRIGVEDDEDLDIGTVKYIVPLYLNGDNVAQNCLEATHVLIKACSIANRIVDDGEGHCFTQQGLAQQWIFHRGEMIFVKAVRIGQLNAYYVDYKNVTNYSLKTAAQVGATISNNLRHGFVDNQQDAYTRLVANYSDTRKWIRDNFTYNYNMEKEKYRITQYHHTHVRLKDLFPSRKIVKLEGYEALLAMMLDRFNNIESTHVTFFTYLRALPDREKEVFISLVLNYNGLGREWLKSEGVRAKQAQGTVKYDMSKLFELNVLENGVDEEVDWEKEKRNRSDIKTVNISYAKVLEHCRELFIMARAEGKRPMRMKWQEYWRQRAVIMPGGSVHSQHPVEQDVIRVLPREIRSKKGVASVMPYKEQKYFTSRRPEIHAYTSTKYEWGKVRALYGCDFSSHTMADFGLLQCEDTFPGFVPTGSYANEDYVRTRIAGTHSLIPFCYDFDDFNSQHSKEAMQAVIDAWISVYHDKLTDDQIEAAKWTRNSVDRMVAHQPNTGETYDVKGTLFSGWRLTTFFNTALNYCYLANAGINSLVPTSLHNGDDVFAGIRTIADGISLIKNAAATGVRANTTKMNIGTIAEFLRVDMRAKNSTGSQYLTRGIATFTHSRVESDAPLTLRNLVSAYKTRYDEILARGASIDNMKPLYRKQLFFARKLFNVEKDIVDNLITMDISCGGLQEKGRVSEMVLQEVDIENIDSYRKTRMIAKLIDKGVGDYTAFLKTNFSEIADAITRETRVESVTKAYNVKKKTVVRAFRDLSAAYHERAVRHAWKGMSGLHIVNRIRMGVSNLVMVVSKINPAKANVLAKSGDPTKWLAVLT
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome.  Catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded from the virion into the cytoplasm where they function as mRNAs for translation of viral proteins and also as substrates for encapsidation to form new virions.  Once encapsidated, the positive strand is converted to dsRNA by the RNA-directed RNA polymerase (By similarity).
What are the official names of this protein?
Probable RNA-directed RNA polymerase, Gag-Pol protein.
What is the protein family that this protein belongs to?
Belongs to the totiviridae RNA-directed RNA polymerase family.
Protein: CH10_LATSS
Sequence: MLKPLEDRVVIAVKDEAEQTVGGIVIASNAKQKPQTGKVVAVGAGAMTSDGQRIPLDVKENDEVIYDKYAGSEVEYEGQQYLVLHAKDIIAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCR_MOUSE
Sequence: MVDSVGFAEAWRAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQPPDGAAEPRASAPRPPPAPADGADPAPVEESEARPDGEGSPSKGRSASARRPAAAASADRDDRGPPTSVAALRSNFEKIRKGPAQPGSADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQQSAGQGLGEAPRPHYRGRSSESSCGLDGDYEDAELNPRFLKDNLINANGGNRPPWPPLEYQPYQSIYVGGMMVEGEGKSPLLRSQSTSEQEKRLTWPRRSYSPRSFEDSGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCQKRHRQCQVVVSEATIVGVRKTGQIWPSDGDSTFQGEADSSFGTPPGYGCAADQAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSLASGALDPTKVSELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMETAEKCCQANAQFAEISENLRARSNKDVKDSTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPSSHPDHSLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHIFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEALPNIPLVPDEELDALKIKISQIKSDIQREKRANKGSKVMERLRKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRESIREQQKKCFKSFSLTSVELQMLTNSCVKLQTVHHIPLTINKEDDESPGLYGFLHVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRILCYEKCYNKMKMTKEDGESADKLMGKGQVQLDPQTLQDRDWQRTVIDMNGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
What is the function of this protein?
Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins.  The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42.  Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form.  The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1.  Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.  The amino terminus contains an intrinsic kinase activity (By similarity).  Functions as an important negative regulator of neuronal RAC1 activity (PubMed:20962234).  Regulates macrophage functions such as CSF1-directed motility and phagocytosis through the modulation of RAC1 activity (PubMed:17116687).  Plays a major role as a RHOA GEF in keratinocytes being involved in focal adhesion formation and keratinocyte differentiation (By similarity).
What are the official names of this protein?
Breakpoint cluster region protein.
What are the subcellular locations of this protein?
Postsynaptic density. Cell projection, dendritic spine. Cell projection, axon. Synapse.
Protein: SCPA_MESM1
Sequence: MNKFEFNLENFDGPLDLLLSLVKDKKADLFTIDLADLATQYLEIINHLEDSNVDVASEYLVMAATLIHIKAKMLLLNPEEEDEEIKEDKEMLLKQLIEYQQFKEVAKKLRQQESIRSEIFIKDPSNYDEYYRETDETLLDGRSNSLSLMNTLRKMFERVHAENLRQTKIEAVHVNPEQRIKEIRDLFDEFGEEVDFAKIFNVPTITHFVITFLVLLDLARKQEIKLIQDKEFGEIRIIKIKGVENEQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
Protein: YIDQ_SHIFL
Sequence: MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATMIGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVIPPARMPDN
What are the official names of this protein?
Uncharacterized protein YidQ.
What is the protein family that this protein belongs to?
To E.coli YceK.
Protein: MDH_MYCMM
Sequence: MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDDCAFPLLSGVEIGSDANKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEVAADDIRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGVAVTDIKKMTIWGNHSATQYPDLFHAEVKGKNAAEVVNDQAWIEEYFIPTVAKRGAAIIDARGASSAASAASATVDAARSWLLGTPADDWVSMAVLSDGSYGVPEGLISSFPVTTKDGNWSIVKGLEIDEFSRGRIDKTTAELADERKAVTELGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: ACKA_HALH5
Sequence: MAINAGSSSLKFQLLNMPEEELVTKGVVERIGLGDGIFTIEVKGEKVTETFDIPDHAFAVKTLLEKLTSHEIIQSLDEIEGIGHRVVHGGEKFNDSVLITDEVIQGIEECNELAPLHNPANIVGIRAFKEVLPNVPAVAVFDTAFHQTMPESSFLYSLPYDYYKEFGIRKYGFHGTSHKYVSQRAAELLGRPIEQLRLLSCHLGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGQTANEVINTLNKKSGLLGVSGFSSDLRDIEEQAGEGNDRAELALEVFTSRIHKYIGSYAARMSGVDAIIFTAGIGENSTVIRERVLRGLEFMGVYWDPSLNQVRGKEAFINYPHSPVKVLVIPTNEEVMIARDTVRLAQ
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
Protein: TPH1_XENLA
Sequence: MYSNRKECPRRVKSFDSVNSGLDENQINNEFNKSTYIKIEDNKEYSENVCERGKASVIFSLKNEIGGLVKALKLFQEKHVNLIHIESRKSKRRNSEFEIFVDCDSNREQLNEIFQLLKPHVNVISMSPPENFTVQEDDMESVPWFPKKISDLDKCANRVLMYGSDLDADHPGFKDNVYRKRRKYFADVAMSYKYGDPIPHIEFTEEEIQTWGTVFRELNKLYPTHACREYLKNLPLLSKHCGYREDNIPQLEDVSRFLRERTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHDSDPLNTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASDEAVQKLATCYFFTVEFGLCKQEGKLKVYGAGLLSSISELKHSLSGNAKVKPFDPMVTCNQECIITSFQELYFVSESFEEAKEKMREFAKTIQRPFGLKYNPFTQSVDILKDTKSIAMVVRELRHELDIVNDALNKMNKQLGV
What is the function of this protein?
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
What are the official names of this protein?
Tryptophan 5-hydroxylase, Tryptophan 5-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: IL13_RAT
Sequence: MALWVTAVLALACLGGLATPGPVRRSTSPPVALRELIEELSNITQDQKTSLCNSSMVWSVDLTAGGFCAALESLTNISSCNAIHRTQRILNGLCNQKASDVASSPPDTKIEVAQFISKLLNYSKQLFRYGH
What is the function of this protein?
Cytokine that plays important roles in allergic inflammation and immune response to parasite infection (PubMed:9366558).  Synergizes with IL2 in regulating interferon-gamma synthesis.  Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity).  Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity).  Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B (PubMed:9366558).  Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils.  Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6.  Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity).
What are the official names of this protein?
Interleukin-13, IL-13, T-cell activation protein P600.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_PSELT
Sequence: MKSKERKSRKRWITDWWPNRLNLKILRQNCSDSNPYGSDYDYLKEVKTLDVDAVIEDLKKLMKTSQDWWPADFGHYGPLFIRLSWHSAGSYRIHDGRGGAKNGSIRFPARINWPDNINLDKAIRLLWPIKKKYGKKLSWADLIILAGTVALQDMGVKILGFSLGREDVFEADESPDWGAEQEMLSGKERFKEGELEKPFAATEMGLIYVNPEGPMGNPDPSGSAKEIRLAFTRMGMNDEETVALIAGGHSFGKCHGAGPSKDLGPDPSSSPIEQMGLGWKYTYKTGKASDTYTSGFEVIWSSKPTKFGIQYLKFLLEFEWELEKSPDGKNQWVAKNAPEMIPDPFDPNKKHKPRMLTADLALKFDPIYSKIAKKFLENPEEFEKAFAWAWFKLTHRDMGPKSCYIGPYVPREEFIWQDPLPKRDYELIDEEDIEYLKKQILNSGINISQLVYTAWSSASTYRDSDRRGGANGARIRLRPMNLWEVNHPDDLIKIIKVYEKIQKNFNEEQKNNKKVSIADLIVLGGCAAIESAAKKAGFDIRVPFIPGRVDALQDQVEEEFYREIEPFADGFRNYFKDPYKIDESDISTTPEYFLIDKAQLLKLTVPELVVIVGGLRVLGAVYSYKNYGVLTHTVGTLTNDFFVNLLDMNIEWKQIDEHRYLFEGFNRKTKEPEFKATRVDLIFAHHDELRAVAEVYASDDEKEKFVSDFIKTWDKVMTLDRFDLKV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RLMN_BURCJ
Sequence: MTSETSVNLLDFDAEGLVAYCGSLGEKPFRAKQLQRWIHQYNAGDFDGMTDLAKSLREKLKGRASIVMPEIASDHVSTDGTRKWLIDVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTAEIIGQLRMAEFALRASLGRAPGPNGKAERVVTNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKYPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLIDAGVVTTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGAAGKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETT1_YEAS8
Sequence: MAKRPLGLGKQSREKKRKVESVEKKSDEPSRESTPVRSQMSVELDDDADLDDELAQLKGLWSKYFHSDRDDEYVLNGIVHECDRLLRLSEEDKEIKKTLNDIFHGIYALALSELTIFKAGDEEATEEKRKKDVSSFFENAIERVELGLSHFPESQFLKLVLAKIIFQRIPLEYISNLHLKSKDKKLDLVGQLEHGKKHFSIYENDTEFTFEILQMVNDLLDIVENFGREQSIQEGIDSDNEEEEELIDIELEPEHPVYPLQQSLEANYEWLRNHFDKLLDNTNTDMKIYASIANTLGELYLKKAEEPSKVFLSLQYDDGSSKKVSDKEAKNVQETALKHTKKALEYLEKAKLEDDPDTWVQVAEAYIDLGNLLDNESAEQEEAYKTAEEILGKANKASHGKFQDVLDNFLQG
What is the function of this protein?
Required for correct translation termination and probably involved in regulation of hypoxic gene expression in association TPA1.  Inhibits replication of Brome mosaic virus (By similarity).
What are the official names of this protein?
Enhancer of translation termination 1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR9_BUCBP
Sequence: MTNRNVIKNVLISVSDTSNIIEFSKSLISKNIKLFATKGTANFLKKNNIYATDITNYTNFPEIMNGRIKTLHHKIYASILAQPKHDKKTIEKYNIILMDIVVINFYPFEEASNNTNLHLNDIIEHIDIGGPAIVRAAAKNYKNVLVVTQPNLYQSIVNEMNLNNNIISETTKLKFATIAFKHTMNYDNNIYQYLSKKNKTVPKNTQLQTLLPSHLTINFKKKQDLCYGENKQQQASWYTNTSKNTSGRMKIKQLQGKILSYNNLSDIHLALSCIHEFNKTTCAIIKHGNPCGVATAKNNDQAYKLAYETDPISAFGGIIVFNQKLNDVTARKIIKTQFSEIILAPDFTQEAKKIFDKKPNLRIIKYDPNYNYLNYNIDIKSIYGDILVQSNTNSIININQWDIVSKKRPNEQEINDAKFALRVVKHLKSNSIVLIKNQITISIGSGQTSRIDATKIAIYKANNNNISLNHTTLASDAFFPFSDSIDLISKSGITCIVQPGGSIRDNEIIMSANKYNISMIFTKQRYFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PYRB_EHRCJ
Sequence: MNTLLEISSLTPDDIESIFNITMQYFNNRSQNNKILNGKVVVNLFFESSTRTLSSFEIAEKSLGAHSITLNINTSSINKGESIIDTILNINAMNPDLIIIRSQYSQLVKTISQYVSNCCIINAGDGNHEHPTQALIDYCTIRYLKKNISNLNISICGDILHSRVARSNIRLLSRYGANISLIAPPTLACDLVGVSHIYHNLIDGIRDADVIMLLRLQKERITNCVIPSEEEYSHLYMLNSERLSYAKKDVIIMHPGPTNKGTEISNNVAENKSVILLQVKMGVAVRKAILHYLLYGNKCNTSNEI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y5020_ARATH
Sequence: MSHFLTFCFLSLLLLLHGANAVTETELRSLLEFRKGIRDETSHQRISWSDTSSLTDPSTCPNDWPGISCDPETGSIIAINLDRRGLSGELKFSTLSGLTRLRNLSLSGNSFSGRVVPSLGGISSLQHLDLSDNGFYGPIPGRISELWSLNHLNLSSNKFEGGFPSGFRNLQQLRSLDLHKNEIWGDVGEIFTELKNVEFVDLSCNRFNGGLSLPMENISSISNTLRHLNLSHNALNGKFFSEESIGSFKNLEIVDLENNQINGELPHFGSQPSLRILKLARNELFGLVPQELLQSSIPLLELDLSRNGFTGSISEINSSTLTMLNLSSNGLSGDLPSSFKSCSVIDLSGNTFSGDVSVVQKWEATPDVLDLSSNNLSGSLPNFTSAFSRLSVLSIRNNSVSGSLPSLWGDSQFSVIDLSSNKFSGFIPVSFFTFASLRSLNLSRNNLEGPIPFRGSRASELLVLNSYPQMELLDLSTNSLTGMLPGDIGTMEKIKVLNLANNKLSGELPSDLNKLSGLLFLDLSNNTFKGQIPNKLPSQMVGFNVSYNDLSGIIPEDLRSYPPSSFYPGNSKLSLPGRIPADSSGDLSLPGKKHHSKLSIRIAIIVASVGAAIMILFVLFAYHRTQLKDFHGRNRFTDQATTRDTKFGRSSRPSLFNFSSNVEQQSSSLSFSNDHLLTANSRSLSGIPGCEAEISEQGAPATSAPTNLLDDYPAASGRKSSSGGSPLSSSPRFSDQPVMLDVYSPDRLAGELFFLDVSLKLTAEELSRAPAEVLGRSSHGTLYKATLDNGHMLTVKWLRVGLVRHKKDFAREAKKIGSLKHPNIVPLRAYYWGPREQERLLLSDYLRGESLAMHLYETTPRRYSPMSFSQRLKVAVEVAQCLLYLHDRAMPHGNLKPTNIILSSPDNTVRITDYCVHRLMTPSGVAEQILNMSALGYSAPELSSASKPIPTLKSDVYAFGVILMELLTRRSAGDIISGQTGAVDLTDWVRLCDQEGRRMDCIDRDIAGGEEFSKGMEDALAVAIRCILSVNERPNIRQVLDHLTSISA
What are the official names of this protein?
Probable inactive receptor kinase At5g10020.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UBIE_ECO24
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EFP_PELUB
Sequence: MKLYASEIRVGMLIEYKNDLWQVLKTQHVKPGKGGAFAQVEMKSVNKNTKLNERFRSSESVEKASLDETKFNYLYSDEIDYYFMDPKSYEQINIKKETIGEKGKMLTENLEVSISFYNEKPLTVELPNQVTCTVDTTDVALKGQTVSSSYKPATLDNGVNIQVPPFIESGDKIIVDTRTMEYVKKI
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTP7_STYPL
Sequence: NNVTIIVMITNLLENGRKKCDQYWPHDGREQYKHISVTLRDVDIYANYIVRSFQLRNTKLSKRRSRNNERRILQYHYTQWPDHGTPEYILPLLKFIRISSVVSSPESGPIVV
What are the official names of this protein?
Tyrosine-protein phosphatase 7.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: RLME_BRASO
Sequence: MAKDTTGRMHVQVKTGGKRKLSSKLWLERQLNDPYVAQAKRDGYRSRATYKLIEIDDKYHMLKPGMTVVDLGAAPGGWSQIAARRVGAEAGKGKVVAIDLLEMGEIPGVTFAQLDFHAQDAPEKLRTMIGGRADVVMSDMAANTTGHRKTDQLRIVGLVELAAHFAGEVLKPGGSFLAKTFQSGADAELLAQLKRDYATVRHVKPAASRQDSSERYVLAMGFRGGEQADLL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1849_KOSOT
Sequence: MYGLINVGFGNVIIGDRVIAIVNPESAPLKRLKEVAKEEGKLIDATYGRKTRAIVITDSNHVILSAIQPETIASRFMQTFTDIEKLLEEIRQAERRTEE
What are the official names of this protein?
Putative regulatory protein Kole_1849.
What is the protein family that this protein belongs to?
Belongs to the RemA family.