PharMolix/UniProtQA huggingface dataset:
Protein: SECA_ANADF
Sequence: MVNYVLRKMLGTKNERELKRLRPLVARVSELEPRMKALSDADFPRLTAEWKQQVRNGRPLDDLMPEAFALVREAGVRALGMRHFDVQLIGGAVLHSGRIAEMKTGEGKTLVATLPSVLNALSGRGVHVVTVNDYLARRDSEWMGRLYRFCGLTTGVIVHGLTDRERQDAYHSDITYGQNNEFGFDYLRDNMKFRLQDYVQGELNFAIVDEVDSILIDEARTPLIISGPSDESSDLYYRVNQVIPSMIRDQDFTVDEKSRTIVMSDSGVEKMEKKLGVQNLYDPNAIETLHHVEQALRAHHLYRNEVDYVVKNGEVLIVDEFTGRLMPGRRWSDGLHQAVEAKEGVKIEAENQTLATISFQNYFRMYSKLAGMTGTADTEAEEFAKTYNLDVVVVPTNKKNVRKDSEDVVYKTEREKFGALCDEIETRHKKGQPVLVGTVSVAKSEVVSSLLKRRGVPHDVLNAKHHQREAEIVAQAGRKGSVTISTNMAGRGTDIILGGNAEMMAKHEVGPEPDLPMEGEAEESFLARKQEWARRLEETRERLRGQTATEHDEVVALGGLHIVGTERHESRRIDNQLRGRAGRQGDPGSSIFYLSLEDELMRIFGSERIQGLMSRMGMKEGEQIEHPWLTKAIEGAQKKVEGHNFDIRKNLLEYDDVMNQQRRSVYRLRRMVLGFGAGVPVVEYDEEPKTRKKTRREQVFTWGDQREHVLDLIEDLVFDMVGASCPNRLSDWNLDGLSSMVKEQFGVEMKFAPPSGKAADARREIEEQVYAVVEKAYRQKEEELGIGPDGEPVLRRYEQWLYLQAIDQQWKDHLLSMDHLRQGIGLRGYGQKDPKQEYKKEGYEMFVQMTWRVKSAVIGNLLRLQLVRQETAEEIEQKRLAAQRRAMQRITETHAAAAGDGEEKPRPKQETVVRTQPKVGRNDPCPCGSGKKYKKCHGATEAAV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: AROE_PARL1
Sequence: MKKVCVIGWPVEHSRSPLIHNYWIGLHGIEGAVYERLAVPPDAAAETIRNLGGLGFIGANVTVPHKETAFAALARHDAIAKRLKAVNTIVTTPAGLEGRNTDGYGFIANLKDRAPGWDAKAGPAVLLGAGGAARAIAAALEDEGAPEIRIINRTPSRAEALARDLGLRNALVFADGEAKTALDGAALLVNTTTLGMKGESDVDLDISPLPAPALVTDIVYTPLETRLLRRAREAGYKTVDGLGMLLHQAVPGFEAWFGVRPQVTPELRALVLADMGMK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PANB_THEVB
Sequence: MVRRSVTLPQLQAKKALGEPITMLTAWDYLWARLLDAAGVDVILVGDSLGMVALGYPTTLPVTLDQMIHHAQAVRRGVSHSFLVCDLPFLSYQESPEQALRSAGRLIKEAEVQAVKMEGASPVVQAATRRLVEAGIPVLGHVGLLPQRVHQLGGWRQQGNTPQDAAAILAGALALAEAGVFAVILEHIPAALAQQITAQLKIPTIGIGAGPHCDGQVLVTADVLGLSPQVPPFAKVYADLGTQAIAAIENYCQAVKSRQFP
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_GLOVI
Sequence: MDPTLAVGLISGTSLDGMDGALVEIAGSAQQPAVTTLATLALPYPAGLRGRLLHLAEGKPVPVAEVSALHRDVALAFADCALQLIEQAGFRCGQIACIGSHGQTVHHQPPADNAAGHTLQLGDGAWIAERTGVTTVGNFRTRDMAAGGQGAPLVPILDYLLLRDARRDRCIQNLGGIANVTYLRAGGGPEEVIAFDTGPANLLIDGTVQIALGEPFDRGGSLALQGTVDRDCLERWLADPYFRRPPPKSTGREYFGYARARRLAEESAHLPVADRVATVSELTVRSIERAYRDFLPRLPDEVFLCGGGARNGYIRARLGRLLAPARVAVSDEAGIDPDFKEAMAFALLAWLRCTGAPGNLPAVTGAGRAVPLGDVHPAG
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: HA14_MOUSE
Sequence: MAPRTLLLLLAAALAPTQTRAGPHSLRYFVTAVSRPGLGKPRYMEVGYVDNTEFVRFDSDAENPRMKPRVRWMEQEGPEYWEQETQNAKDHEQSFRVSLRNLLGYYNQSKGGSHTIQGMRGCDVGSDWRLLRGYEQFAYDGPDYIALNEDLKTWTAADMAAQITRRKWEQAGAAETLRAYLEGACVEWLRRYLELGNATLLCTDPPKAHVTHHPRSEGKVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWAALVVPLGKEQNYTCHVEHEGLPEPLTLRWEPPPSTDSYMVIVAVLVVLGAVFIIGAVVAFVMMMRRNTGGKGGDYTLAPGSQSSEMSLRDCKVMVHDSHSLA
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, D-P alpha chain, H-2D(P).
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: VP3_ROTHD
Sequence: MKVLALRHSVAQIYADTQVYTHDDSKDDYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAIEIQKIDELFTLIRCNFTYDYIDDVVYLHDYSYYANNEIRTDQYWVTKTNIEDYLLPGWKLTYVGYNGSDTRGHYNFSFRCQNAATDDDVIIEYIYSNELDFQNFILKKIKERMTTSLPIARLSNRVFRDKLFKTLSVNHDKVVNVGPRNESMFTFLDHPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDMYHEKPIIYMIGSAPSYWIYDVKQYSDLKFETWDPLDTPYSNLHHKELFYINDVQKLKDNSILYIDIRTDRGNMDWKEWRKVVEGQTADNLHIAYKYLSTGKAKICCVKMTAMDVELPISAKLLHHPTTEIRSEFYLMMDIWDSKNIKRFIPKGVLYSYINNTITENVFIQQPFKLKTLKNEYVIALYALSNDLNNREDVVKLINNQKRALITVRINNTFKDEPKVGFKNIYDWTFLPTDFEMNGSIITSYDGCLGIFGLSISLASKPTGNNHLFILSGTDKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTGKASIEGGKYYEHAPIELIYACRSAREFAKLQDDLTVLRYSNEIENYINKVYSITYADDPNYFIGIKFKNIPYKYNVKVPHLTFGVLNISEQMLPDAIAILKKFKNELFGMDITTSYTYMLSDEVYVANISGVLSTYFKIYNAFYKEQITFGQSRMFIPHVTLSFSNEKTVRIDTTKLYIDSIYLRKIKGDTVFDMTE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: YCGN_SALSV
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLLTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SCPL1_CAEEL
Sequence: MTYAESTRSAVVYSSIVPPPRTPVGPPMLKDGVRKGSASQPLQPKNGANSLDYWSKSEDEKSGITCYYSRHNIQFPPPQRKMKPVKPNPVGRSTINGFTPSTSSPQNGLRYPPFPQNTPESVMSPPVGIYRNIPAMPRAKLTKDEKNGGKMNRDGGGENPKNVVWGGTSRKDDDTASTPLNSFSANASIEKKRSTARRKPRWARCFQTLFCCVTPPREIEKIQSSQRTNSTNNNHQNGRPSTPTNTGPPIQLITQVHRDGTVTGLPTTGQACQQNGSGDGVTPYDKIANDSVGTINEKPLLPPLLPQDSNKKCLVIDLDETLVHSSFKPVKNPDFVIPVEIDGVEHQVYVLKRPYVDEFLAKVGEHFECILFTASLAKYADPVADLLDKKRVFRGRLFREACVFHKGNYVKDLSRLGRNLNQTLIIDNSPASYAFHPENAVPVTTWFDDPSDTELLDILPSLEHLNGFSSIYDLYRPEEGPQSELLNHCSC
What is the function of this protein?
Phosphatase which may play a role in the egg laying muscles.
What are the official names of this protein?
CTD small phosphatase-like protein 1, SCP-like 1.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line. Note=Colocalizes with unc-89 at M line.
Protein: F16PA_GLOVI
Sequence: MDTTPLTPLTKGITLYQHILSQQALNPDATGEFSGLMVQISLAAKLISRQLAQAGLVENVLGFTGETNVQGEAVRHLDQYANETFIRVFQNTNLVCLLVSEELEDPLPLSNQCPIGSYALVIDPVDGSSNIDVNVSVASIFSVQRRNPRATDETSSLLQKGTGQVAAGYVLYGPNTMFVYTSSQGVHGFTLDAGLGEFVLSHPNIRIPERGDYYSINDAYSAEWQPGTRAFIDYLKQAKSRGEKAYSARYIGSLAADVHRTLLTGGIFLYPGTVAKPKGKLRLLYEAQPLALIAEQAGGKASTGTERILDIEPKTLHQRVPLVIGSPYEVDLAVAFARGEKQTVVAGS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_HPV5B
Sequence: MAVWHSANGKVYLPPSTPVARVQSTDEYIQRTNIYYHAFSDRLLTVGHPYFNVYNITGDKLEVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWACRGLEIGRGQPLGVGSTGHPYFNKVKDTENSNAYITFSKDGQNTAFSKDDRLNTSFDPKQIQMFIVGCTPCIGEHWDKAVPCAKNDQQTGLCPPIELKNTYIEDGDMADIGFGNMNFKALQDSRSDVSLDIVNETCKYPDFLKMQNDIYGDACFFYARREQCYARHFFVRGGKTGDDIPGAQIDNGTYKNQFYIPGADGQAQKTIGNAMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGILWANQMFITVVDNTRNTNFSISVYNQAGPLKDVADYNAEQFREYQRHVEEYEISLILQLCKVPLKAEVLAQINAMNSSLLEDWQLGFVPTPDNPIQDTYRYIDSLATRCPDKNPPKEKEDPYKGLHFWDVDLTERLSLDLDQYSLGRKFLFQAGLQHTTVNGTKAVSYKGSNRGTKRKRKN
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: VG55_BPN15
Sequence: MNPSPLIAAIKAWWKPLFVLIFAASAFIAGNVWSNRAWEKRWADRDSAESSQKVNAQTAARMIEQGRIIARDEAVKNAKEKAAAARDASARLAGTVSQLQQQARKLATRLDAAKHTADLAAAVRGKTAGANAAVLADMLGSLAAEAKYYAERSDESYRAGMTCQRIYDSVRESNNQSGASQ
What are the official names of this protein?
Protein gp55.
What is the protein family that this protein belongs to?
To E.coli rzpQ.
Protein: FBX22_PONAB
Sequence: MESVGCCGDCRGSSVDPRSTFVLSNLAEVVERVLTFLPAKALLRVACVCRLWRECVRRVLRTHRSVTWISAGLAEASHLERHCLVRVVAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLGIVTPGIVVTPMGSGSNRPQEIEIGESGFALLFPQIEGIKIQPFHFIKDPKNLTLERHQLTEVGLLDNPELRVVLVFGYNCCKVGASNYLQQVVSTFSDMNIILAGGQVDNLSSLTSEKNPLDIDASGVVGLSFSGHRIQSATVLLNEDVSDEKTAEAAMQRLRAANIPEQNTIGFMFACVGRGFQYYRAKGNVEADAFRKFFPSVPLFGFFGNGEIGCDRIVTGNFILRKCNEVKDDDLFHSYTTIMALIHLGSSK
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function (By similarity).
What are the official names of this protein?
F-box only protein 22.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line.
Protein: M7G_CONCN
Sequence: MKLTCVVIVAVLLLTACQLITADDSRGTQRHRALRSDTKLSMSTRCKGKGASCRRTSYDCCTGSCRSGKCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like CnVIIG.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FENR_PARXL
Sequence: MSSAANLPSPSPSPPIRTDVLIVGAGPVGLFAAFEAGVIGLSCQIVDGLDKVGGQCIELYPDKPIYDIPAIPSCTARELVERLLAQCRPFDPPIHLEQRVESVEQGGDGRWTVRTDRGLVFDVAAILLAAGNGAFVPQKLALAEAVPLESRHVHYSVPRLADFAGKTVVVAGGGDSALDWALALRKVARRVTLVHRRSGFSAADSSVESMRRAVEAGEMDFVVGAIAGLDVEDDALKSITLRHIEGETQLAAEHLVALYGLVADLGPIAQWGLSIHGGRVDVDTSNYESSRPGIFAVGDIAHYPNKQKLILSGFHEASLALRKAYSYAYPEKKRVHVHSSYDAKLAEKVSAAG
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: MTA_TREBE
Sequence: MDPCQCSKSGTCNCGGSCTCTNCSCKSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: Y2639_BURVG
Sequence: MDARLLEILVCPICKGPLHYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGPAGS
What are the official names of this protein?
UPF0434 protein Bcep1808_2639.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MKRN2_SERQU
Sequence: MSTKQVTCRYFLHGVCREGSRCLFSHDLNNSKPSTICKFYQRGVCAYGERCRYDHIKPSSRGGGGGAPEDQAGGGGAGGGGAGIGGAGGGPSVRGGMKKNLVLRDRVLGVDRVDRMFGAPADSMWSDVSTAAAPHSYVEAIRTGLDASAQDQATPPVCGPSQNLPQLCPYAANGHCFYEENCTYLHGDLCEVCGLQVLHPHDSEQRRAHEKMCLAAFEADMEKAFAAQLSQDKVCSICMEVVVQKANPSDRRFGILSSCCHTFCLACIRKWRCTRTFSNTIIKSCPECRVVSEFVIPSVYWVEDQEDKDHLIDLFKSGVSKKACKYFDQGRGSCPFGGKCLYLHAFPDGTRAEPDRPRKQLSSEGNVRFMNSVRLWDFIEEREQRSVPPLPALDDDMAELRELFMQMSGPSHDGPETPPTADQ
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity).  Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway.  Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression.
What are the official names of this protein?
E3 ubiquitin-protein ligase makorin-2, RING-type E3 ubiquitin transferase makorin-2, Zinc finger protein YGHLC3HC4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUSB_CLOBB
Sequence: MNRKLSREKAMELLFGMTLNTDNCEETLENFIDNYESDIKELDITYIKRILIGVENNKDNIDESISKNLCNWKIDRISKVNLCILRLAVYELLHDEEIPNRVAINEALEITKKYSDEKSVSFVNGVLDNILKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ARNE_YERE8
Sequence: MTSYLLLITVSLLTCAGQLCQKQAAQSWALPQHYRLAPTLRWLASAVVLLSLGMLLWLRLLQHLPLSVAYPILSFNFVLVTLAAQFFYGEQATSRHWLGIASIMFGILLISWHL
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_PARPJ
Sequence: MSSEAKCPFNHAAGGGTTNRDWWPKQLRLDLLSQHSSKSDPLDGSFNYAEAFKTLDLAAVKKDLAALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLLILTGNVALETMGFKTFGFAGGRPDTWEPDQDVYWGNEKTWLGGDVRYGKGAAGNEEDGGVIVADVEKHGEEVSRDDNGRILENPLGAVQMGLIYVNPEGPDGNPDPLAAAHDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPADNVGPEPESAELEEQGLGWKNSYGSGKGADTITSGLEVTWTTTPTKWSNNFFENLFKYEWELTKSPAGANQWVAKGADETIPHAHDPSKKQRPTMLTTDLSLRFDPAYEKISRRFLENPDQLADAFARAWFKLTHRDMGPRARYLGPEVPAEELIWQDPIPAVNHPLVDEQDIASLKQKILASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWAVNQPEQLSKVLKTLEGIQSEFNGAQSGGKKVSLADLIVLAGSAGIEQAAKSAGHQVTVPFAPGRMDASQDQTDVESVGALEPVADGFRNYVRSDIKVPPEALLIDKAQLLTLTAPEMTVLIGGLRALNVGTGQNPQGAFTDKPETLTNDFFRNLLDMGTEWKPTSPARHAFEGRDAKTGSVKWTGSRVDLVFGSHAQLRALSEVYASEDGKEKFVRDFVAAWVKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ZN823_HUMAN
Sequence: MDSVAFEDVAVNFTQEEWALLGPSQKSLYRNVMQETIRNLDCIEMKWEDQNIGDQCQNAKRNLRSHTCEIKDDSQCGETFGQIPDSIVNKNTPRVNPCDSGECGEVVLGHSSLNCNIRVDTGHKSCEHQEYGEKPYTHKQRGKAISHQHSFQTHERPPTGKKPFDCKECAKTFSSLGNLRRHMAAHHGDGPYKCKLCGKAFVWPSLFHLHERTHTGEKPYECKQCSKAFPFYSSYLRHERIHTGEKAYECKQCSKAFPDYSTYLRHERTHTGEKPYKCTQCGKAFSCYYYTRLHERTHTGEQPYACKQCGKTFYHHTSFRRHMIRHTGDGPHKCKICGKGFDCPSSVRNHETTHTGEKPYECKQCGKVLSHSSSFRSHMITHTGDGPQKCKICGKAFGCPSLFQRHERTHTGEKPYQCKQCGKAFSLAGSLRRHEATHTGVKPYKCQCGKAFSDLSSFQNHETTHTGEKPYECKECGKAFSCFKYLSQHKRTHTVEKPYECKTCRKAFSHFSNLKVHERIHSGEKPYECKECGKAFSWLTCLLRHERIHTGEKPYECLQCGKAFTRSRFLRGHEKTHTGEKLYECKECGKALSSLRSLHRHKRTHWKDTL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 823, Zinc finger protein ZFP-36.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFE_YERPY
Sequence: MSEAKKLLAQGLWKNNSALVQLLGLCPLLAVSSTATNALGLGLATTLVLVCTNTAVSALRRWVPSEIRIPIYVMIIASVVSTVQMLINAYAFGLYQSLGIFIPLIVTNCIVIGRAEAYAAKNPVGLSALDGFAMGMGATCALFVLGALREILGNGTLFDGADMLLGSWATVLRIDILHLDTPFLLAMLPPGAFIGLGLLLAGKYVIDEKMKARKANTRVSVPQLQDGDAEKAL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATG18_YEAST
Sequence: MSDSSPTINFINFNQTGTCISLGTSKGFKIFNCEPFGKFYSEDSGGYAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQIYIYDINTMRLLHTIETNPNPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTYATRIYSISFSEDSQYLAVTGSSKTVHIFKLGHSMSNNKLDSDDSNMEEAAADDSSLDTTSIDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSRRAARTLGQIFPIKVTSLLESSRHFASLKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSASTESYHEPVMKMVPIRVVSSDGYLYNFVMDPERGGDCLILSQYSILMD
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  May negatively regulate FAB1 activity by sequestering or masking VAC7 from FAB1.  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication.  With ATG2, protects ATG8 from ATG4-mediated cleavage.
What are the official names of this protein?
Autophagy-related protein 18, Cytoplasm to vacuole targeting protein 18, Needed for premeiotic replication protein 1, Swollen vacuole phenotype protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Requires VAC7 for vacuole membrane localization. Under mid-log phase growth, localizes to the vacuolar membrane; but when cells are starved, is almost completely released from the vacuole membrane.
Protein: RDRP_I05A1
Sequence: MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLENSHPGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEIFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFHRKRRVRDNMTKKMVTQRTIGKKKQRLNKKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNELTKKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: RF3_STRPQ
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSW_BUCAI
Sequence: MKHLQKKNSKNPKKIEEKYNTRNSYFILYDRALVWLTLGLFSVGLIMVISTSIPISQKIYHNPLFFIKREIFYFFLIFLLSFIFLRTPIIFWEKNSNIILIISIVLLVLVLLIGHSIHGSFRWINIGFLHIQPSEICKISSFCYLASYLSRKSNEVRNNFWGFFKPMSVIITQSMLLLAEPDLGTVVVLFFTTISVLFLSGAKIGQFFIIITVSILTIILLILLEPYRIKRVLSFWNPWEDPFGNGYQLTQSLIALGRGNFLGQGLGNSIQKLDYLPDAHSDFIFSIIGEELGYIGSFLILLIIFTISFRAMYIGQKALEKKQIFSGFLACSIGIWLSFQTSINVGSVTGILPTKGLTLPFISYGGSSLIINSIAIFFLLRIDFETRLKTSQAFPRGPK
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.