PharMolix/UniProtQA huggingface dataset:
Protein: ZPLD1_MACFA
Sequence: MEQIRLLLLLTIRVLSGSAQFNGYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVSAYGNATSVQIGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYNQQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDIRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPFLMPICSHRERRDAGRRTTWSSQSSSGSAVLSAGPIITRSDETPTNNSQLGSPSVPPFQLNAITSALISGMVILGVMSFSLLVCPLALLHRKGPTSLVLNGIRNPVFD
What is the function of this protein?
Glycoprotein which is a component of the gelatinous extracellular matrix in the cupulae of the vestibular organ.
What are the official names of this protein?
Zona pellucida-like domain-containing protein 1, ZP domain-containing protein 1, Cupulin.
What are the subcellular locations of this protein?
[Zona pellucida-like domain-containing protein 1]: Cytoplasmic vesicle membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Zona pellucida-like domain-containing protein 1, secreted form]: Secreted, extracellular space, extracellular matrix.
Protein: MNMG_ECO5E
Sequence: MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSDDKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL5_SIGHI
Sequence: MRMLLHLSILTLACVWTFAVEIPMHTVVKETLIQLSTHRALLTSNETVRLPVPTHKNHQLCIGEIFRGLDILKNQTVRGGTVETLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMGTEWTMEH
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils.  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_AZOVD
Sequence: MATINQLVRQPRKRLVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGYEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKDRKQGRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TAMB_SALTS
Sequence: MSLWKKISLGVLIFIVVLLASVAFLVGTTTGLHLVFSAANRWVPGLEIGQVTGGWRDLSLKNIRYEQPGVAVNAGEIHLAIGLDCLWRSSLCVNDLALKDINVAIDSKKMPPSEPAQEEEESGPLNLSTPWPITLSRVALNNINIKIDDTTVSVLDFTSGLAWQEKNLTLKPTRLQGLLIALPKVADVAQEEVVEPKIEKPQPDEKPLGETLKDLFAKPVMPEMTDVHLPLNLNIESFRGEQLRITGDTDLTVRTMLLKVSSIDGNMKLDTLDIDANQGTVKASGTAQLANNWPVDITLNSTLNIDPLKGEKIKLKVGGALREQLEVGVNLSGPMDVALRAQTRLAEAGLPLNLEVVSQRIAWPLTGDTQFQADDLKLKLSGKMTDYTLSMRTAVKGQDIPPATITLDAKGNERQINLDKLTVAALEGKTELKALVDWQQAISWRGELTLNGINTAKEIPDWPAKLNGVMKTKGSLYGGTWQMDVPELKLTGNVKQNSVNVNGTLKGNSYMQWTIPGLHFALGPNSADIKGELGVKELNLDAAIDAPGLDNALPGLGGMAKGIVKVRGTVEAPQLLADITARGLRWQELSVAQARIEGDIKSTDQIAGHLNVRVERISQPDVNINLVTLDAKGSEKQHQLQLRVQGEPVSGQLSLTGSFDREAARWKGTLSDTRFQTPVGPWSLTRAIALDYRNKEQKISIGPHCWLNPNAELCIPQTIDAGAAGRAVVNLNRFDLAMLKPFMPDTTQASGIFSGKADVSWDTTQEGLPQGKVTLSGRNVKVTQTVNDAPLPVAFETLNLSADLHNNRAELGWLIRLTNNGQFDGQVQVTDPQGRRNLGGNVNMRNLNLAMVNPVFSRGEKAAGMLNARLRLGGDVQSPQLFGQLQLSALDIDGNFMPFEMQPSQLTMNFSGTRSTLAGIVRTQQGQINLNGNADWSQIDNWRARVTAKGSRVRITVPPMVRLDVSPDVVFDATPSLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNNDLQPETPQTASIPINSNLTVHVGNNVRIDAFGLKARLTGDLKVAQDKQGLGLNGQINIPDGRFRAYGQDLLVRKGELLFSGPPDQPLLNIEAIRNPDATEDDVIAGVRVTGTADEPKAEIFSDPAMPQAEALSYLLRGQGLDSNQSDSAAMTSMLIGLGVAQSGQVVGKIGETFGVSNLALDTQGVGDSSQVVVSGYVLPGLQVKYGVGIFDSLATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF
What is the function of this protein?
Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane. Substrate binding to TamA moves its POTRA domains about 30 Angstroms into the periplasm, which would deform either the outer membrane or TamB and may provide force to reset TAM.
What are the official names of this protein?
Translocation and assembly module subunit TamB, Autotransporter assembly factor TamB.
What is the protein family that this protein belongs to?
Belongs to the TamB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HLDE_HALHL
Sequence: MTPPLPGFRDVRVVVAGDLMLDRYWHGATQRISPEAPVPVVRVDGAEERPGGAANVALNVAALGGEAQVVGPTGSDEAADRLAELLEAAGVGQRFHRIAGADTITKLRVISRHQQLIRLDFERGFPGFDHAAMLALLEPALADAAVLVLSDYAKGALPDPAGLIEAARRAGRPVLVDPKGADYRRYRGASLLTPNLAEFEAVVGPCADGDEIAKRARQLAADLELEALLVTRGEAGMTLAPREGVAVHLPTRAREVFDVTGAGDTVIATLAAALGAGVDLADASALANVAAGVVVGKLGTATVTPAELEAALGGGPAPAAGSGVVDEPGLLAAVRQARAAGERIVMTNGCFDLLHAGHVDYLQRARRRGERLVVAVNDDASVARLKGAERPVTPLAQRMAVLAALDTVDWVVPFSEDTPARLIEAVLPDRLVKGGDYQPEQIAGHDVVVAAGGSVEVLPLLAGASTTDLIARIRSRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CAIA_SALHS
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_BURP6
Sequence: MSEPIDLSQISPALKAEILAEALPYIRRYHGKTVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDQALKKIGKQGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVTLINHFGGHAVGLTGKDGGLIHARKLMMPDRDNPGEYVDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLVMMTNIPGVMDKEGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y395_CAMJJ
Sequence: MKKIKKIIQIGMIGGLAAVAGGALAGCGSNNDNADTLNQAANAQGAFVIIEETAPGQYKIKDQYPSDETRVVLKDLNGTERILSKEEMDALIKEEAAKIDNGTSNLTKDNGQISSGGLSLGETLLASAAGAILGSWIGSKLFNNQNFANQQRGAFSNQSAYQRSVNSFNKAGTTSSASSAKKSGFFGGGSKATSSSSSFGS
What are the official names of this protein?
UPF0323 lipoprotein CJJ81176_0395.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MUTS_KORVE
Sequence: MNDPTTPLMKQWAQVKRDHPNALLFFRLGDFYELFFDDAVIAARELQITLTARNKEKGNSVPMCGVPYHAAENYISKLIRRGFKVAVCDQVEDPKLAKKLVKREVTRVMTPGTTADSQLGSEENNFLAAVASHGDFVGFAALDLSTGEFRATEFKGSDARRRIQEELLTLRPREILYGSSLPLFDAARPANAVSGAMPKLATVEGASWAETPLEDWVFAPDYAIPLVENHFGVLSLEGFGLANKASAASAAGAILHYVRQTQRGSLHHVDRIGFYERQNCLVLDAVTVRNLELIEPLFTNTGEGVTLFRALDATMTPMGKRLLRAWMLRPSIDTSEINARLDAIEMQVVDTLGREELRRAMDGILDIERLLSRVTLETANPRDLLALAQCFGRLPKVRAAMQRFTSARFLVLHGLLDDLADLRDRIFTTLVDEPPITLNDGGVVREGLDAALDELRNLSHNSKQFIAQIEERERKRTGIGSLKIKFNNVFGYYLEISNANKHLAPADYERKQTLVNAERFTTPELKEYEAKVLDAQEKIVEIERRIFGELRTAIAAEARRVRQTGLALAEVDVLANFAHLAATRNYCRPKFDQSGEFELIEARHPVIELPELTGSADRFVPNDLYLNATTHTVIVLTGPNMGGKSTYLRQAALVAVMAQMGSFVPARSARLSVVDRVFTRIGAADNLARGRSTFMVEMTETAAILNTATDRSLILLDEVGRGTSTYDGLAIAWACIEFLHARTRAKALFATHYHELTVLADELSGVKNYHVSVKESGGNVVFLRRVEPGAADKSYGIEVAKLAGLPAEVIERARAVLKEHESVERQATSHLSKDERGSDSMQLTIFTPLSQKIVDQLKETDLNRLTPIEALNLLHELKKQLD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PROF_HEILC
Sequence: MSFNDKAAEAVASGDIGVGWLLSDQCEVFWNVGSWEGANPCEILTEWKKSAMTPITIAGLKFTIIGKTPERLVSTNIGGQGHIVGAKCTNYPGYLVCWCPATVGPNIAYSVIQKLADLVKA
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations inhibits spontaneous rabbit actin nucleation.  This strongly suggests this archaea has a profilin-regulated actin system, and actin-type genes can be identified in this organism.
What are the official names of this protein?
Heimdall profilin.
What is the protein family that this protein belongs to?
Belongs to the Asgard profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TSAD_GRABC
Sequence: MDFPASENLFPGPVLGIETSCDETAAAVLDGSGRILAEIVLSQYDDHARFGGVVPEIAARAHLAYLPGMVTEVMDKAGLRFQDLAAIAATSGPGLIGGLLVGAGLGKGLALAAKRPFIAINHLEAHALAALLPALGGVAEITSGEHFPFLLMLLSGGHCQCILVEGVGRYRRLGGTIDDAVGEAFDKVGKLLGLGWPGGPALERLALQGNPHALAFPRPMKGRVGCDFSFSGLKTAVAQYVARFPDGPLPLSDAADIAASFQAAVADVMADRATAALAMADEIAPAKMLVVSGGVAANAAIRAALSTAAEHRGIAMLAPPPRLCTDNAVMVAWAGLHRLKYGAVSGLDHAPLPRWPLDAPDMALPESTTP
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2898_BURM9
Sequence: MLSLAKIAALFVLTAVAEIVGCYLPWLVLKAGKPAWLLAPAALSLALFAWLLTLHPAAAARTYAAYGGVYIAVALAWLRIVDGVPLSRWDVAGAALALAGMSVIALQPRG
What are the official names of this protein?
UPF0060 membrane protein BMA10229_A0598.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BPIA2_RAT
Sequence: MFQLGSLVVLCGLLIGTSESLLGDVANAVNNLDILNSPSEAVAQNLNLDVGSLQQATTWPSAKDSILETLNKVELGNSNGFTPLNGLLLRVNKFRVLDLQAGLSSNGKDIDLKLPLVFEISFSLPVIGPTLDVAVSLDLLNSVSVQTNAQTGLPGVTLGKCSGNTDKISISLLGRRLPFVNRILDGVSGLLTGAVSILLQNILCPVLQYLLSTMSGSAIQGLLSNVLTGQLAVPL
What is the function of this protein?
Has strong antibacterial activity against P.  aeruginosa.
What are the official names of this protein?
BPI fold-containing family A member 2, Neonatal submandibular gland protein, Parotid secretory protein, PSP.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
What are the subcellular locations of this protein?
Secreted.
Protein: YHBQ_ECOK1
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAVFAELLSSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: LEUD_BUCAI
Sequence: MFKFTGHAGIVVPLDISNIDTDIIIPKQFLKRVNKIGFGKYLFHDWRFIDANQLVKNEDFILNKKIYKNASILLTRENFGCGSSREHAVWSLVDYGFKVIIAPSFADIFYNNSFNNKLLLITLSSSEITFLFDIVKNNIGITFDVSLVEKTVTVNKEVFSFELDDFHYFCLLNDLDNIDLTMKHLSEIKSYESRISDFLLERRDFQS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CAP4_ACIS2
Sequence: MSASLLEKQSTGGAIARVGFGYQDAFVLRSLPLWLSQSAFSHIVSEALSDIEVCYFSSEKSLHVMYEAKNHSLTATEFWDEIRRFKSLFDTHPKNFIWFNLVCPSYNTAISPLISKIDRLRGVGSSYDDDSSVSVNGRSEYLDWCVGKKIDFSLAEFALDYVGFITFNSENSESIFLSEIQDTINIELLRSQVKQLKDQFKNLISRSSFGPIYRKDFENFICHALEEDRSQWLLDPIKINLSASSSQYQDLNLDISDFNGPDRAQKTSSDWNSLIKKAVSIGDFIHNSGDRRTLLIDGKQRMSTACMLGYVFSATRNFLLEIEHNGLIYRTDDHKQKEGQFFTKIEAVEPQGETEAIVAIGFPTAIGKDIDSTINEVKSLPRLNLESSHAIDNMETLNLAVREAKSALVSFKSENKLSKLHLFIKAPSVFAMVLGHRLNGICDIQLYDWVDGQYIPTAELNL
What is the function of this protein?
Binds cyclic nucleotide second messengers (synthesized by CdnD, the cognate CD-NTase in the CBASS operon).  Ligand binding activates it to endonucleolytically degrade dsDNA to approximately 6 bp length fragments, with a preference for 5'-C or 5'-G cleavage site.  The minor product of CdnD is the activating nucleotide; also binds the major product (2',3',3'-cyclic AMP-AMP-AMP) but is not activated by it.  Only binds DNA in the presence of ligand.  Is not activated by c-di-AMP, c-di-GMP, 3'3'-cyclic GMP-AMP (3'3'-cGAMP) or 3',3',3'-cyclic AMP-AMP-GMP.
What are the official names of this protein?
CD-NTase-associated protein 4, Cap4, Endodeoxyribonuclease Cap4.
What is the protein family that this protein belongs to?
Belongs to the Cap4 nuclease family.
Protein: RL362_HAEDU
Sequence: MKILNSLKTAKSRHPDCQIVRRKGKLYVICKTNPRFKARQR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DPH3_MOUSE
Sequence: MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFAITKEDLENGEDVATCPSCSLIIKVIYDKDQFMCGETVPAPSTNKELVKC
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase.  Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3, CSL-type zinc finger-containing protein 2, DelGEF-interacting protein 1, DelGIP1.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPG_MYCA9
Sequence: MGAQIRELRRRIKSAGAIKKITKAQELIATSRIAKAQARVVAARPYATEITNVLTALADDAALDHPLLVERPEPKRAGVLIVSSDRGLCGGYNANVLRVAEELYALLREQGKTPVVYVVGRKALNYYSFRNRKVTEAWTGFSERPEYASAQKIADTLVEAFLAGADDEGDDPGLDGILGVDELHIVYTEFKSMLTQAAVAKRIAPMEVEYVGEAAGPTTQYSFEPDATTLFGALLPRYLATRVYAALLEAAASESASRRRAMKAATDNADELIKGLTLEANGARQAQITQEISEIVGGVNALADAAGH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VME1_CVBLU
Sequence: MSSVTTPAPVYTWTADEAIKFLKEWNFSLGIILLFITVILQFGYTSRSMFVYVIKMIILWLMWPLTIILTIFNCVYALNNVYLGFSIVFTIVAIIMWIVYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGRMYVRPIIEDYHTLTVTIIRGHLYMQGIKLGTGYSLSDLPAYVTVAKVSHLLTYKRGFLDKIGDTSGFAVYVKSKVGNYRLPSTQKGSGLDTALLRNNI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: RLMN_STAHJ
Sequence: MITTEKKKKNKFLPDFEKQSIYSLRYDEMQEWLVEHGQQKFRAKQIFEWLYQKRVDSIDDMTNLSKDLRQVLKDNFAMTTLTTVVKQESKDGTIKFLFELQDGYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKALDATDERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIYDFAEEDIQINFAVSLHAAKDEIRSKLMPINRAYHVDKLMEAIKYYQEKTNRRVTFEYGLFGGVNDQLEHARDLAHLIKDLNCHVNLIPVNHVPERNYVKTPKDDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  Confers resistance to some classes of antibiotics.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRB_SHIF8
Sequence: MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLLVIIQVLPLFLLLSITTGAIPALLTGVMVACLPEKIGSQKNYRCLAGGIGGVVITEIYCAVIVHIKGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS
What are the official names of this protein?
Inner membrane protein CbrB.
What is the protein family that this protein belongs to?
Belongs to the CbrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_CHLTB
Sequence: MGQKGCPVGFRTAVTKKWRSLWYGNNQEFGKFLIEDVKIREFLKKKPSCQGAAGFVVKRMSGKIEVTIHTARPGLVIGKKGAEVESLKAELKKLTGKDVWVEIAEVKRPELNAQLVADGIAKQIERRVSFRRAMKKALQSVMDAGALGVKVQVSGRLAGAEIARSEWYKNGRVPLHTLRADIDYATASAETTYGIIGIKVWINLGEKKAVPAANHAGAASTAAA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL11_STRP8
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTRAQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: OSMR_RAT
Sequence: MAFSVVLHQVTFLLAVLSLRTSQSKVLGEPLQLTPEIHTVSLQSALQEANLEWTVPTFSHQELNIVFQIEISRMRTSNTIWVGNYSTTVKHEETVHWKWTSDIPLECATHFIRIRAMVDDAQYPPQSSWSNWSSWKEVNAQVSVPPDTLLIFPEDRLLEEGSNVTICLMIGQNLYNVSCKLQEEPIRGEQLDSHLSLIKLNNVVFLNNAGTNINCKAMNGTKNTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGIDTTLSWHKQRSQHYTLYESFSGRREVSNHRNSHTWQITEDSQETYNFTLTAENNLRKRSVSISFNLTHRVHPKAPHDVTLKTVGATKAHMTWKVPSRGDYTLLCQVELQCEGEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASANHFWKWSDWMQKKFRTPEAAPSEALDVWRDVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHEEVHEKTIKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFERSVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAGQGPNETYTKVTTPDVRSHMLLQIILPMTLGVFLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHTEDVPTKPPLVPTEKDSSGPMPFVFLENFTYDQSAFDSGSHGFIPGPLKNTPHQLGLLAPPNKLQNVLENDYMKSLVESPTEETSLIYVSQLASPICGDKDSLVTNPPMPVHGSEYKKQMALPGSLTSASLKENNLTS
What is the function of this protein?
Associates with IL31RA to form the IL31 receptor.  Binds IL31 and activates STAT1, STAT3 and STAT5.  Capable of transducing OSM-specific signaling events (By similarity).  The OSM/OSM-R system is pivotal in the differentiation of oval cells into hepatocytes, thereby promoting liver regeneration.
What are the official names of this protein?
Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS19_LAWIP
Sequence: MPRSLKKGPFVDKDLMKKVDAAIANNDRRVLKTWSRRSTILPEMVGLTFAVHNGKKFLPVFITENMVGHKLGEFSPTRTFYGHAGDKKTKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.