PharMolix/UniProtQA huggingface dataset:
Protein: TG198_CAEEL
Sequence: MRLYFVLIFSVIFTTGNGKIQCKNMRGKSVDWFVVYKLPKLSGAGTSGKEFVYFDAESSDWTRGNDINDPNVAVGATVSQVYSADKSNNFWFMYSDDDPIKSADSYRGHAKGVSLFDSTTGFWLIHSVPNFPPIKSFSYPNTAEKYGQSFFCASMEVQHLTELAEHWKYIQATPYIINIPEKYATRFPTLKNVEAKQSLPRSATQFWISKPIKTVQGVTLMAYAKHKKFDGDIWNDLISRQNKVTLAVESWLNGSGDDIHTTCTSTSQTHDVTEMRVTGLNFASSKDHSKWAVSNSQTNPIVCFGDMNRQKSQLKRGGGALCIQNRNLWQLYHSFVIQVEPCKSSSHFSMFQTIATLLSAAGLVSKI
What are the official names of this protein?
Cell-death-related nuclease 7.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
Protein: 045R_IIV3
Sequence: MYKCSQGAMNTEKVMEKFVIQSRFREMYPDKAKAIAGMTVPARYADSVEDMVAFANEKIRVQKAKVEAEKNARQAMGAPAKFDKYGKYKY
What are the official names of this protein?
Uncharacterized protein 045R.
Protein: HYPC_AZOVI
Sequence: MCLAIPVRIEELLDEQSAVACIGGLRKTINVALLDDLKVGDYVILHVGFALQKLDEAEAQRTLALLAELGRLAEAEQAAQGEAP
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor.
What are the official names of this protein?
Hydrogenase maturation factor HypC.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: VE41_NPVOP
Sequence: MDRVASQIYSGALPYITTMDMEDRLRNRIAAKAGAKFFKACFEAVVADKSGLFVLSGGAATACHIGDDRNVLKCLDFDYYNATQEWLQLARLQQRLQACVQDNLEILSRLAQSVRMQDDLFVVKCFQNGAFCFNGPVQARLVPCVETVRTSFNGEFDLLRFALQVELKALNGVDEYVDQKVIVDRGAAVFNVFFVNIRAMKGPLTMERCVRTLAVFGDAYRVVVSPLQSVINDQIMCLLKDIFTDKPEFRVARPKALICALFAKLPREAYDECINSHHGAEPTRRRDETVTSFCRRTLHIHGPALGCRKLVYAYFKTDSFARQMPDYVANRAIYPHTDCEMKWKEFIHFFVVAKV
What is the function of this protein?
This protein is required for viral late gene expression.
What are the official names of this protein?
Putative early 40.3 kDa protein.
Protein: BIOB_CLOAB
Sequence: MKNQWNNILSIGEKVLNGEKITADEALTLSKSNGSDIFLLCSFANKLREKFNGNHVDLCSVINAKSGNCSEDCAFCAQSAHHKANVSCYPLLNEDKILEMAKQREAYGARHCDIATSGLGYTGDEKDFQTILKAFKKMKENTNLKLCACLGTLTEKAMNSLAAVGVERYNHNLETAKSFYKNIVSTHGYDERIKTINYAKNAKMEVCSGMIVGLGETMEQRIEHALLLRDLNVDAVPVNILNPVKGTKLENAKPLSPMEIIKTFAIIRFILPDKIIRYAGGREKNLRSLQPLGFLSGLNGMLIGNYLTTNGQSVNDDFNMLKDLELEY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SYC_GEOMG
Sequence: MSLRVYNTLSGTKEEFTPLVPGRVSMYVCGVTVYDHCHIGHARANVVFDMIYRYLRHAGYDVTYVRNYTDVDDKIINRANQEGVPYNAISERFIAEFDRDMAALGLDLPTHQPKATEHIAEMIDVISRLIEKGFAYAADGDVYFCVEKFDPYLKLSKRNLDEMQAGARIEVGEKKRHPMDFALWKGSKPGEPFWESPWGQGRPGWHIECSAMSMKYLGETFDIHGGGKDLVFPHHENEIAQSEAANGKPFAHYWIHNGFVNINSEKMSKSLGNFFTIKEVLEKYDAEVLRFFLLSAHYRSPIDFSDQNLREAEAGLERIYGTLAGIDENLTKGAEGTAEETDRELAEKAVTFPERFREAMDDDFNTAQALGFVFDLVRSANRVLGEGKGGGSNRALLAEARDRIRKVGAVLGIFTSEPRAFAERLKNRKAAELPITAEEIERLIAERIAARANRDFKRADEIRDSLAAKGIMLLDSPQGTTWKVK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_SHESH
Sequence: MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHNKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMKAAVEMAKDWRSDKMLRKLEALLAVADDTCSLIITGNGDVVQPENDLISIGSGGNFAQSAATALLENTELSALEIAEKSLTIAGDICVFTNQFKTIEELNY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SENP6_MOUSE
Sequence: MAAGKSGGSAGALFLKALDRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSEISKGKKLNRRSEIVATSSGDFILKTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHSQTPGIRTAAQRKEYPPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQLSPLSPASKKCLTHLEVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYIQTNGKVILPGGKIPKLTNPKERKISVSDLNDPIILSSDDDDDDDDRTKRRESTSPKPADSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVIPRKARMKDQLGNSISTPLKRRKVNSHAAFIHPMSLSCQNFESVILNCRSIRVGTLFRLLVEPVIFSLESITIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQAEVVFESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQKENKVKTVSFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKTPSAEDSCVSSASEMGACSQNSAAKPVIKKMLNRKHCLAVTDSSAAQEESEPCYRRNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSENGLRDECFSSVHHPDALSKIRLNYGDQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPVLNFELPMNLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDGAEQYASASGGSE
What is the function of this protein?
Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins.  Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors.  Deconjugates SUMO1 from RXRA, leading to transcriptional activation.  Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex.  Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation.  Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.
What are the official names of this protein?
Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_ALTMD
Sequence: MSMQDPIADMFTRIRNGQMAQKVSVTMPSSKLRVAICEVLKAEGYITDFAASGDVKPVLEVTLKYFEGKQVIDTIERVSRPGLRIYKKKDELPKVMGGLGVAIVSTSKGVMTDRAARNAGMGGEIIGYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NUDL_YERPY
Sequence: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: ATPB_MYCPN
Sequence: MKKENITYGKVHQVIGPVVDVIFTESSQLPRIYDCLSVKLAGEELFLEAAQLIGDDIVRCIALGPTEGLARNEKVTNYNHPIEVPVGKNVLGRMFNVLGKPIDGKEELPKKPQLPIHRKPPSFDDQSNTLEIFETGIKVIDLLTPYARGGKIGLFGGAGVGKTVLVQELIHNIAKEHSGLSVFAGVGERTREGNDLYYEMIQGGVIDKTALVFGQMNEPPGARMRVALTALTMAEYFRDHDNQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERIASTKTGSITSVQAIYVPADDLTDPAPATTFTHLDAKTVLDRNIAALGIFPAINPLESTSRLLDPNIVGINHYKVALGVQNILQRFAELQDIIAILGIDELADEDKIIVERARRIRNFLSQPFFVAEKFSGIAGKYVPLSDTIQSFKEILDGKHDDLPEQAFFFVGTIQEAVEKAKRLKKATVEEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YDA5_SCHPO
Sequence: MPSLVRRFQHASTEEQPFELNIQMESPPLVMYGNPDVSSGALASGLAKLTVFPADLKCESIVMEFVRIISTKRPLRDSCPDCKAQVEAFEKWEFSKEPTVYTHGTHTWPFTFIIPGHFPQTTNSPFINVTYILKTRVKIPSQPDFVFEYPLNLKRSIVTNADKIAQRLFPPTSLIALLELPPVIHPLSCVPVEFQLTGVKPENSKVGWRLTKISWRIEEQIKAQINGCSTHTGTKKPYIFKETRLLGNNEHKSGWKEDGDRIIFEIPISTSLLSKPICDVSFDGQFSLYIAHQLILETIVVEVMNSHPINSNARILRMKVNLPLTERGGLGVSWDEECPPMFNSVGPSPPAYEQVARSSPTDIPLPPPSCPTNVQRD
What are the official names of this protein?
Uncharacterized protein C1F12.05.
Protein: RBFA_VARPS
Sequence: MPKRKAAAPNRAFKVADQIQRDLTELIARELKDPRVGMVTIQAVEVTPDYAHAKIYFSMLTGDVTETTEALNQAAGFLRNGLFKRLHIHTVPTLHFLFDRTTERAADMNALIAQAVASRSKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSZB_DICDI
Sequence: MTILNRFCRTILLTNLELTNCGIRKNNSYKCRSFTHTINIDTNHIVPIHTQSNITLELFQPKISVVGVGGGGGNAVNHMISQSLEGVEFFVCNTDSQDLIKSNSINKIQLGPQLTKGHGAGANPEKGRLAAEESKNKIIQTFKDTDLLFLAAGMGGGTGTGSSPIIAKTIKEFKKETIIVGVVTVPFNFEGKRKEIIAKKGLEELSKYVDTLVVISNQNLLDASKSDIQLEQAFLMVDEILHTGIRSIANIINVPGMINLDYSDVVNILKNRKGLSRIGFGEASGEDRAYKAVHKAIKNPLIEIDDQKFTGLLVNISGGNDITLNEISKTINYLQQNADPDVQVFVGHTVDNSLLGKIRISCLFVH
What is the function of this protein?
Probably involved in mitochondrion division process.  Binds to and hydrolyzes GTP (By similarity).
What are the official names of this protein?
Mitochondrial division protein fszB.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
Protein: RL17_RICPU
Sequence: MRHKIKGRKLNVTSSHRQAMLANMAVALVTHEQIKTTLPKAKELRPYIETLITKAKKADLMVRRSVLSKIKDKTAVEKLINILGTRYKDRPGGYTRIIKAGFRYGDLAPIAYIEFVDRDINAKGNIQQDANEEIKN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y005_MYCCT
Sequence: MISDFNNQEITLEDLEQNNVKLKEGKAKVQFLMRFSLVFSNIFTHIFLFLLIIVSGLFFGLRYTYYNYKIDLITNVYKIKPSIPKLKEIYKEVLEVVDEVKRETDKNSEDSLINKIDEIRGIVKEVTNIAKEFDEKSKEVKPKVEKVIQEGKQVTSNLDKITKEIQALQVNGNGLASRVRRSLTGDINTITNLANNIDFDFNSVKESIEKITGLAQQISKEGKSITKNVEEIKNEVEYFTGKSKEPLKDIDKIKQIYDKKIPIFEKNNKKLQEIWNKLMGIYNEFTVKETKKDYYNYVIYILLFLIIDSLILLVITYMSMISKTIKKLLLFYIFGLLSFNPIVWASIIISLFSRPIKNRKNKFY
What are the official names of this protein?
Uncharacterized protein MCAP_0005, ORF L5.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNMC_LEGPH
Sequence: MSSPFVPIITADIDWRDDLPYSLQFDDIYYSAEGGINQSLYVFVEGNNLINRWQQLPTNESNVFTIAETGFGTGMNFLLTWKLWEKFAPQNARLHYISCDKHPLKKNDLIKCLQKWPELSVQAEKLIAHYPVLTPGYHHLTFSNNQITLTLMLGDVLECYEQLLFCGDINLEHQLRESYVNAWYLDGFSPSKNQSMWSDNLFTVIAMLSKESTTVATYSASSIVKTALTNAGFVIEKRKGFGPKRHMICAHYEKAYSSSKKNRHTPWHINYPVTKDERTALIVGGGLAGCFIANSLAKRGWEVTILEEKEKVGCGGSANQQAVLFPKLSTYKSPFTQFMLYSFLYANDVYKELLKYYDLGELKGSLLLAHNEKEKANQQSLIHWLELYPELGQLVDEKQSSELSGISLPCGGLFIPSSGWINSPELCDILIDNKRISLITGNRVQSINYNQKNWVVNGIEASVLILANGQQVNYFHETNHLPVKAIRGQMTTIQSTQESTKLKIPLCAEGHVLPALNNSHKVGASYDIGTSEPELNALDDQLNLARLKRIAPDIMWSQNVLDHWAGIRAASPDYLPIVGPLPNALEFKEIYSELKSNSKRWIAEAAPCYPNLYVCAAFGSRGLTTIPLATEWLAGLINKEISILPRKLIQAISPARFLRKKIIQGP
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_ENT38
Sequence: MNNTTEYIDALPLTDIEKAALPKSDIRAVHTALDGEHHPFSRDDDTPLGSVKARLEQAWPDSLAEGQLIKDDEGRTQLQAMPKATRSSMFPDPWRTNPVGRFWDRLRGREVAPRYLSRLTKEQQASEQKWRTVGTIRRYTLLLLTLAQTVVATWYMKTILPYQGWALINPADMFGQDVWVSFMQLLPYILQSGILLLFAVLFCWVSAGFWTALMGFLQLLMGRDKYSISASTVGDEALNPEHRTALIMPICNEDVDRVFAGLRATWESVKATGNAAHFDVYILSDSYNPDICVAEQKAWMELIAEVQGEGQIFYRRRRRRVKRKSGNIDDFCRRWGNQYSYMVVLDADSVMTGECLTGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRVQPFIEHCALAPLPGEGSFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPELAIALFASTMILLFLPKLLSIILIWCKGSKEYGGFCRVTLSLLLEVLFSVLLAPVRMLFHTVFVVSAFLGWEVVWNSPQRDDDSTPWSEAFKRHGSQMLLGLVWAAGMAWLDLRFLFWLAPIVFSLILSPFVSVISSRSTMGLRTKRWKLFLIPEEYSPPQVLVDTDKYLVLNRSRSLDDGFIHAVFNPSFNALATAMATARHRASQVLEIARDRHVEQALNETPEKLNRDRRLVLLSDPITMARLHYRVWSAPERYSSWVNYYSTIKLNPLAIKSK
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDR_CHRVO
Sequence: MKCAFCGNPDTQVIDSRVSEDGSSIRRRRRCPACDKRFTTFETADVRMPQVVKTAGHRSEFDIEKVRTSFLRALHKRPVSTTLVDEAIDRICHKLLQLGEREVSSRQIGEMVMNELARLDKVAYVRFASVYRSFQDISEFTDAIKEIQKSSH
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: THIE_BACAN
Sequence: MSRISKAEMSKLLSVYFIMGSNNCTKDPLQVLREALEGFITIFQFREKGEGALTGEERICFAKELQAICKEYGVPFIVNDDVELALELDADGVHVGQDDEGITSVREKMGDKIVGVSTHTIEEARWVIENGADYLGVGPIFPTSTKKDTKAVQGTKGLAHFREQGITIPIVGIGGISIENTASVIEAGADGVSVISAISLAESAYESTKKLVEEVSRSL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RAF1A_WHEAT
Sequence: MARFLVALLATTLVAVQAGGQLGHAAPATAEVFWRAVLPHSPLPDAVLRLLKQPAAGVELLTEATSFVRDAEDRPPFDYRDYSRSPPDDEPSKSTGAASGARDFDYDDYSGGDKLRGAASGARDFDYDDYSGADKLRGATDEYKAPSSSLAGNGASMARGGKAETTTVFFHEEAVRVGKRLPFRFPPATPAALGFLPRQVADSVPFTTAALPGVLATFGVASDSATVASMEATLRACESPTIAGESKFCATSLEALVERAMEVLGTRDIRPVTSTLPRAGAPLQTYTVRSVRPVEGGPVFVACHDEAYPYTVYRCHTTGPSRAYMVDMEGARGGDAVTIATVCHTDTSLWNPEHVSFKLLGTKPGGTPVCHLMPYGHIIWAKNVNRSPA
What is the function of this protein?
Required for pollen development.  Probably synthesized in the tapetum, packaged in Ubisch bodies and transported at appropriate stages to the micropsores.
What are the official names of this protein?
Protein RAFTIN 1A, TaRAFTIN1a, BURP domain-containing protein 1A.
Protein: EI3D1_DROSI
Sequence: MSETINTAAQFPSFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSSNDKKYQNKYASSFGTGNQYSYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKVFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEPKYKFEESNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQQVYNYAHNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10A2_BOVIN
Sequence: MSSPLEQALAVMVATFHKYSGQEGDKFKLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGDLDENSDQQVDFQEYAVFLALITIMCNDFFQGSPARS
What is the function of this protein?
May function as calcium sensor and modulator, contributing to cellular calcium signaling.  May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes.  May also play a role in suppressing tumor cell growth (By similarity).
What are the official names of this protein?
Protein S100-A2, Protein S-100L, S100 calcium-binding protein A2.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: DNAJ_BORPD
Sequence: MAKRDYYEVLGVAKNATDDELKKAYRKLAMKHHPDRNPDNKDAEEKFKEIKEAYEVLGDEQKRAAYDRYGHAGVDPNAAGMGGAGMGGGFADAFGDIFGEIFGGAGGRRGGAQVYRGADLKYALEITLEQAAHGFDTEIRVPSWEHCDTCHGSGAKPGTSPKTCRTCGGSGAVRMQQGFFSVQQTCPTCHGTGKEITDPCPSCDGVGRIRRNKTLQVKIPAGIDDGMRIRSSGNGEPGINGGPSGDLYVEIHIKPHKIFQRDGDDLHCELTIPFTTAALGGELQVPTLGGKAEISIPEGTQSGKTFRLRGKGIRGVRASYPGDLYCHVAVETPVRLSDEQKAILRQFETSLNDGGDRHSPQSKSWTDRVKEFFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEKJ_SCHPO
Sequence: MTTCSICNESEIKYKCPKCSFPYCSLPCWKIHQSQCETVNDNNTTTFKGVKEPLNPPEPSPNVIYVNGRIPSLAEEALPSESLLESIVEDPSIKNLIESNAELLHIMKELVNLDREEEGSVPLKTLDAIQQQRLHNPSFEKLASMILEKYYAQK
What are the official names of this protein?
Uncharacterized zinc-finger protein C4F10.19c.
Protein: DNAJ_SHELP
Sequence: MSKRDYYEVLGVGRDASEREIKKAYKRLAMKFHPDRNPGDKAAEASFKEVKEAYEILTDSDKKAAYDQFGHAGVDPNRGGGGFGGGADFGDVFGDVFGDIFGGGRRGGQRQAARGSDLRYNLELSLEEAVRGLTKELRIPTLATCDLCDGSGAKKGSSPTTCGTCHGQGQVQMRQGFFAVQQACPTCHGRGKIIKDPCGKCHGEGRVEKSKTLSVKIPAGVDTGDRIRLSGEGEAGEFGAPPGDLYVQVTVREHAIFVRDGNNLYCEVPISFSTAALGGEIEVPTLDGKVNLKIPSETQTGRMFRLRGKGVKSVRSHAVGDLLCKVVMETPVNLNDKQKELLREFDNTLTGSSKKHSPKAEGFFDGVKKFFQDLNS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_MYXXD
Sequence: MSEHTFARASHLSELEAESIHILRETVAEFANPVMLYSIGKDSQVLLHLARKAFHPAPLPFPLLHVDTTWKFRDMYAFRDAFVARHGLRLIIHRNQRALAEGINPFDHGSQKYTHAMKTQALLEALAAHGFDAAFGGARRDEEKSRAKERVFSFRDRHGQWDPRRQRPELWNLFNGRVDAGESMRVFPLSNWTELDVWHYVLRERIPVVPLYFAAERPVIDRGGTLLMVDDERMRLRPGEKPEIRRVRFRTLGCYPLSGAIESSATTVETVIHEMVNARQSERQGRLIDHDEEGSMELKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: HIS3_BRUME
Sequence: MSIFPAQPSDKKAVEEGAAFMPRFDASGLITAIVTDARDGELLMVAHMNEEALRLTLETGIAHYWSRSRKTLWKKGETSGNLQSVVELRTDCDQDALWLKVHVAGDGPTCHTGRRSCFYRQVVSSGGKVALTMASDHDQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_MYCTU
Sequence: MTERSDRDVSPALTVGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELERVLARSAGILGIELGADAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALEVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVATALAWTHLGMTPPVGASQPGLFE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvB binds Holliday junction (HJ) DNA in the presence of RuvA (PubMed:22094465).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.