PharMolix/UniProtQA huggingface dataset:
Protein: PB1F2_I51A0
Sequence: MGQEQGTPWILSTGHISTQKGEDGQKTPKLEHHNSTQLMGHYQKTMNQVVMPKQIVY
What is the function of this protein?
May play an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm, host cytosol.
Protein: NUOK_TOLAT
Sequence: MNGIPFEHGLIVAAILFSLGLCGLLIRRNLLFILMSIEVLMNASAVAFVVAGSRHGQVDGQIMYILVISLAAAEASIGLALLMRMYRRHHTLNVDSVKEMHG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP16A_HUMAN
Sequence: MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAQGKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSLLRRRTSSAGSRGKVVRRVSLTQRTDLYRKQHAQEAIVWQQPPPTSPEPPEDNDDRQTGAELRPPPPEEDNPEVVRPHNGRVGGSPVRHLYSKRLDRSVSYQLSPLDSTTPHTLVHDKAHHTLADLKRQRAAAKLQRPPPEGPESPETAEPGLPGDTVTPQPDCGFRAGGDPPLLKLTAPAVEAPVERRPCCLLM
What is the function of this protein?
Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3.
Protein: PMRR_ECOLI
Sequence: MKNRVYESLTTVFSVLVVSSFLYIWFATY
What is the function of this protein?
May bind to BasS and modulate its sensor kinase activity.
What are the official names of this protein?
Putative membrane protein PmrR.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS13_THEKO
Sequence: MTENFRHIVRVAGVDIDGHKQVRWALTGIKGIGINFATMVLRVAGIDPFMKAGYLTDEQVKKIEEILADPVAHGIPAWAVNRPKDYETGKDMHLITAKLVMAWREDVNRLRRIRAYRGIRHELGLPVRGQRTRSNFRHGTTVGVSRRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ATG12_VANPO
Sequence: MSGMLLESESDHEDSEISSGYSENGRLMSQDPLSLSTGNVMQSRLEQYSKRLSQLGLAATDGDSNGDGTDNDIIPSEYDEEEISVPKQEVPMTTSLILDKLPPTTNEFLHQLSIKEMEQDIEKTVHKIQIKFQPIGSIPLITPSVCTISSQQTFSMIILFLKKRLKVEQVFCYINNSFAPNPQQTIGSLWSQFKVNDELIVSYCGTVAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: Y3990_BACLD
Sequence: MKNLEQTWRSILDEFHQQANLREGHIVVIGCSTSEVAGRRIGTSGSEQIAEAVYKGLEELRDRTGIALAFQCCEHLNRALVVEEETAKAYRLPVVFAIPVPKAGGSMASYAYKHMKAPVLVEQIEADAGIDIGDTFIGMHLKPVAVPVRVSQKQLGEAHVTLARTRPKLIGGVRAVYEAE
What are the official names of this protein?
UPF0340 protein BLi03936/BL03990.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: AIMR_BPSPB
Sequence: MELIRIAMKKDLENDNSLMNKWATVAGLKNPNPLYDFLNHDGKTFNEFSSIVNIVKSQYPDREYELMKDYCLNLDVKTKAARSALEYADANMFFEIEDVLIDSMISCSNMKSKEYGKVYKIHRELSNSVITEFEAVKRLGKLNIKTPEMNSFSRLLLLYHYLSTGNFSPMAQLIKQIDLSEISENMYIRNTYQTRVHVLMSNIKLNENSLEECREYSKKALESTNILRFQVFSYLTIGNSLLFSNYELAQENFLKGLSISVQNENYNMIFQQALCFLNNVWRKENKWINFESDSIMDLQEQAHCFINFNENSKAKEVLDKLDLLVHNDNELAMHYYLKGRLEQNKACFYSSIEYFKKSNDKFLIRLPLLELQKMGENQKLLELLLL
What is the function of this protein?
Transcriptional regulator which is part of the latency-replication switch system that decides at the onset of infection whether to replicate and lyse the host or to lysogenize (latency) and keep the host viable.  Activates the transcription of the aimX locus.  Transcriptional activation of aimX seems to lead to the productive viral replication (lytic cycle), aimX possibly acting as a regulatory non-coding RNA.
What are the official names of this protein?
AimR transcriptional regulator, Arbitrium communication peptide receptor, YopK protein.
Protein: GLMU_MYCSK
Sequence: MTSSTTSSTDTAVLVLAAGAGTRMRSDIPKVLHTLGGRSMLAHALHTVAKVAPQHLVVVLGHDRERIAPAVEALATDLGRPIDVAIQDQQLGTGHAAECGLAALPEDFTGVVVVTAGDVPLLDADTMADLLATHGSAAATVLTTTVDDPTGYGRILRTQDNEVTSIVEQADASPSQRAIREVNAGVYAFDITALRSALRRLRSDNAQHELYLTDVIAIFRQDGLSVRARHVDDSALVAGVNDRVQLAALGAELNRRIVTAHQRAGVTVIDPGSTWIDVDVTIGRDTVIRPGTQLLGRTRVGGRCDVGPDTTLSDVTVGDGASVVRTHGSESLIGAGATVGPFTYLRPGTALGAEGKLGAFVETKNATIGAGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGETKNRTTIGSHVRTGSDTMFVAPVTVGDGAYTGAGTVIRRNVPPGALAVSAGSQRNIEGWVVRKRPGSAAARAAERASGEAAEQALGHHDDSQGS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_MYCA9
Sequence: MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVPEARMVVIKPYESNQLKAIEDAIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGKGEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDLDKTTAQYVSQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX27_CENLI
Sequence: TVIDVKCTSPKQCLPPCKEIYGRHAGAKCMNGKCKC
What is the function of this protein?
Inhibitor of voltage-gated potassium channels (Kv).  This protein is capable of displacing the binding of radio-labeled noxiustoxin (AC P08815) to rat brain synaptosomes with high affinity (about 100 pM).  It is also capable of inhibiting transient potassium-currents (resembling I(A)-type currents), in cultured rat cerebellar granule cells.  About 50% of the peak currents are reduced by application of a 1. 5 uM solution of this toxin.  Is lethal to mice (when less than 100 ug are injected).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.7, C.1.limpidus toxin 2, CllTx2, Toxin II.10.9.2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: POTA_STAS1
Sequence: MEPLLSFKSVSKQYDDMQILDKIDIDIESGYFYTLLGPSGCGKTTILKLIAGFEEADNGDIIYQGKSINHLSANKRKVNTVFQDYALFPHLNVYDNIAFGLKLKKLAKSEIKRKVHEALKLVKLEGYESRTIEGISGGQKQRIAIARAIVNEPEILLLDESLSALDLKLRTEMQYELREIQSRLGITFIFVTHDQEEALALSDYIFVMKDGKIQQFGTPIDIYDEPVNRFVADFIGESNIVEGKMVKDYLVNIYGQDFECVDMGIPEQKKVEIVIRPEDISLIDAKSGLFEVTVDSMLFRGVHYEINCIDRKGYEWMIHSTKKAEVGSKVGLYFDPEAIHIMVPGETEEEFDKRIESYEEQDNA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: XYLA_SALEP
Sequence: MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHDVDVSPEGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELDKRVAKRYAGWNSELGQQILKGQLSLGELAQYAEQHNLAPVHQSGHQELLENLVNRYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ICTPU
Sequence: MGRMHAPGKGLSQSALPFRRSVPTWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILVESRIHRLARYYKTKRVLAPNWKYESSTASALVA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NIA_EMENI
Sequence: MSTTVTQVRTGSIPKTLKTSQIRVEEQEITELDTADIPLPPPSKEPTEVLSLDKTTPDSHVPRDPRLIRLTGVHPFNVEPPLTALFQQGFLTPPELFYVRNHGPVPHVRDEDIPNWELRIEGLVEKPITLSFKQILQNYDQITAPITLVCAGNRRKEQNTVRKSKGFSWGSAALSTALFTGPMMADIIKSAKPLRRAKYVCMEGADNLPNGNYGTSIKLNWAMDPNRGIMLAHKMNGEDLRPDHGRPLRAVVPGQIGGRSVKWLKKLIITDAPSDNWYHIYDNRVLPTMVTPDMSSQNPSWWRDERYAIYDLNVNSAAVYPQHKETLDLAAARPFYTAKGYAYAGGGRRITRVEISLDKGKSWRLARIEYAEDKYRDFEGTLYGGRVDMAWREACFCWSFWSLDIPVSELASSDALLVRAMDEALSLQPKDMYWSVLGMMNNPWFRVKITNENGRLLFEHPTDITGSSGWMEQIKKAGGDLTNGNWGERQEGEEPVEAEPVVEVNMKKEGVTRIIDLEEFKKNSSDERPWFVVNGEVYDGTAFLEGHPGGAQSIISAAGTDASEEFLEIHSETAKKMMPDYHIGTLDKASLEALRKGNADTTDSSSDPRPTFLTPKAWTKATLTKKTSVSSDTHIFTLSLEHPSQALGLPTGQHLMLKTPDPKSSSSGSIIRSYTPISPSDQLGMVDILIKIYAETPSIPGGKMTTALDTLPLGSVIECKGPTGRFEYLDRGRVLISGKERFVKSFVMICGGTGITPVFQVLRAVMQDEQDETKCVMLDGNRLEEDILLKNELDEFEALAGKKEKCKIVHTLTKGSESWTGRRGRIDEELIRQHAGTPDRETMVLVCGPEAMEKASKKILLSLGWKEENLHYF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADPH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: KUP2_CUPNH
Sequence: MNGETPDASHPQQSRAELTLAALGVVYGDIGTSPLYAVKETFNPAHGIPLVTENILGGISAILWALMVVVSLKYVILIMRANNRGEGGIMALLALALSSVKKVGRSPTPILLVGLFGAALFYGDAVLTPAMSVLSALEGIEVGTTALQPYVLPASVGVLIALFLFQRHGTAAIGALFGPVTIVWFLALAAAGIHGIARYPAILGALSPLHALGFVTQHGFASFAVLGAVLLAFTGAEALYADMGHFGSAPIRLAWFGLVFPALALNYLGQGALIIVNAKAIENPFYLLYPSWALYPMVALATAATVIASQATISGAYSLTKQGIQLGYLPRMNVVHTSERAIGQIYIPTLNGMLLVAVLVAVLGFGSSSNLASAYGVAVTGTMLVTTLLTFFVIHYGWRYNLLLSLVATGFFIAVDMAFVSSSLLKVAEGGWFPLVVGAGIFVVMLTWVRGRQALLERLQSTDVPLKSFLDSLFLAPPPRVPGTAVFLTPTPDVVPHALMHNLNHNRVLHERVVFLTVKMKDVPSVPATECAAVEPLGHACYRITLRFGFMNRPDVAQALGALPPAAGLEFDIMDTSFFLSREAIVAAAGGPSGMASWRERLFATMSRNAGNAADYFNIPANRVIEIGTQIKI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1825_MYCTO
Sequence: MSENRPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPRSKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGDSLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALESAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAGAEAIQINDAHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIGDPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQPVK
What are the official names of this protein?
UPF0749 protein MT1873.
What is the protein family that this protein belongs to?
Belongs to the UPF0749 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCD_ENT38
Sequence: MSWIERIKSNIAPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGTMVELGSELEPKDLLKFRDSKKYKDRIASAQKETGEKDALVVMKGTLHEMPVVAAAFEFSFMGGSMGSVVGARFIRAVEQALEDNCPLICFSASGGARMQEALMSLMQMAKTSAALGKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIQKGAIDMIVRRPEMRLKLASVLAKLMNLPAPSPDEPRESVVVPDQEPEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD3_AMAEX
Sequence: MSDINVIRAPLLILSILPCVGDDIEVLRRGEGLS
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24050899).
What are the official names of this protein?
MSDIN-like toxin proprotein 3.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: SHC1_BOVIN
Sequence: MNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPRLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGALPGAARPTPPSAQTPSHLGATLPVGQPAGGDPEARRQMPPPPPSSGRELFDDPSYVNVQNLDKARQAGAGAGPPNPTINGSAPRDLFDMKPFEDALRMPPPPQSTAMAEQLRGEPWFHGKLSRREAEALLQVNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
What is the function of this protein?
Signaling adapter that couples activated growth factor receptors to signaling pathways.  Participates in a signaling cascade initiated by activated KIT and KITLG/SCF.  Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).
What are the official names of this protein?
SHC-transforming protein 1, Src homology 2 domain-containing-transforming protein C1, SH2 domain protein C1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_ECOLC
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RS21_RUEST
Sequence: MQVSVRDNNVDQALRALKKKLQREGVFREMKLKQHFEKPSEKKAREKAEAIRRARKLARKKAQREGLL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NDK_CHLSY
Sequence: MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFNGLVSYITSAPVVVAVVAGKPGTVELVRAMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDSPESGERETAIFFQPHELIGEWNRALDNWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAPN_PEA
Sequence: MAATGVLAEIIDGDVYKYYADGEWKKSTSGKSVAIINPTTRKPQYKVQACSQEEVNKVMDSAKSAQKSWAKTPLWKRAELLHKAAAILKEHKAAIAECLVKEIAKPAKDAVTEVVRSGDLVSYCAEEGVRILGEGKFLVSDSFPGNERTKYCLTSKIPLGVILAIPPFNYPVNLAVSKIAPALIAGNSIVLKPPTQGAVAALHMVHCFHLAGFPKGLISCVTGKGSEIGDFLTMHPGVNCISFTGGDTGIAISKKSGMIPLQMELGGKDACIVLEDADLDLVAANIIKGGFSYSGQRCTAVKVVLVMESVADALVEKVKVKVAKLSVGPPEDDSDITPVVSESSANFIEGLVNDAKEKGATFCQEYKREGNLIWPLLLDNVRPDMRIAWEEPFGPVLPVIRINSVEEGIHHCNASNFGLQGCVFTKDINKAIMISDAMESGTVQINSAPARGPDHFPFQGIKDSGIGSQGITNSINMMTKVKTTVINLPSPSYTMG
What is the function of this protein?
Important as a means of generating NADPH for biosynthetic reactions.
What are the official names of this protein?
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)], Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase, Triosephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPOTE_SERLI
Sequence: MTDTLSPWHLYMLRLPNGMLYTGITTDVERRLAQHQAGKGAKALRGKGELVLAFHCLAGDRSKALRLEYRVKQLSKTQKERLVNHPPLTLDHLLPDAEIKTG
What are the official names of this protein?
UPF0213 protein in potE 3'region.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: Y4123_YERPB
Sequence: MSAIALTVSMLALVAVLGLWIGNWKIYGVGLGIGGVLFGGIIVGHFAQTYQIVLNGDMLHFIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNCFAILMVVVGGLVTAIIHKLFAVPLPIILGVFSGAVTNTPALGAAQQILTDLGSPPQLVSQMGMGYAMAYPFGICGILLVMWLIRLFFKINIDREAKAFDSSYGQNRELLQTMNVAVRNPNLHGLSVQDVPLLNSDEVVCSRLKRGDLLMVPMPATVIEIGDYLHLVGQRDALEKVRLVVGEEVDVTLSTAGTALQTARVVVTNEAVLGKKIRDLNLKQKYDVVITRLNRAGIELVASNSANLQFGDILNLVGRPEAIEAVSAIVGNAQQKLQQVQMLPVFIGVGLGVLLGSIPLFVPGFPAALRLGLAGGPLVVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFINTLVNGDGLAWIGYGAMITGIPLLTVGILARMLVKMNYLTLCGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQILAVLFWTL
What are the official names of this protein?
Putative transport protein YPTS_4123.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACT1_ECHGR
Sequence: MAEEITPLVVDNGSGMCKAGFAGDDSPRAVFPSLVGRPRQQSIMVGMGNKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVRAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDWLTKLLTERGYAFTTTAELEIVRDIKEKLCYVALDFENEMATAATSSSLEKTYELPDGQVITVGNERFRCPEALYQPSFLGLECNGIHETTYNSIMKCDLDIRKDLYSNVVLSGGSTMYPGIADRMNKDLTALAPTTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: URE1_MYCTA
Sequence: MARLSRERYAQLYGPTTGDRIRLADTNLLVEVTEDRCGGPGLAGDEAVFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIISGNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTVNPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGHAPDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSDSQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEPAFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADVRAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQC_PSEU2
Sequence: MSEATALSPAEFEQALRAKGAYYHIYHPFHVAMYEGRATREQIQGWVANRFYYQVNIPLKDAAILANCPDREIRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVGLDPDQLRSQELVLPGVRFAVDAYVNFARRANWQEAASSSLTELFAPQIHQSRLDSWPQHYPWIDPAGYEYFRTRLGQARRDVEHGLAITLQHYTTYEGQQRMLEILQFKLDILWSMLDAMSMAYELNRPPYHSVTDQRVWHKGITL
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: DKF2_CAEBR
Sequence: MDANDFPRLFYTSMPSSSTSNHRIDRLSSSSSSTFRRDDFRRHSTTTSSEKFSTISIGESVKLEEENGEIPEKFVQEEDTVVKTEETRVSDCDFSLTFYTAHVTSSSMLSRGDSSSINNKTFTPDDHYSNPSDKRREVPSIRSTSSNSSSFGGHVAFVDEPSEENQRQQQQYQQHQFQLPTLLVTSTPSTVFDQNDDDVFTSPYHPPNRQYSSSSEMSGLSFQLQSGIHKKSIAVEGNEIALRDLRNEAFQFVKEIYPEKKCGSLEDYILLYKHDLRSINILQLITTSSDVTDGTLVEIVIGSCPQNERIVVHPHTLFVHSYKVPTFCDFCGELLFGLVKQGLKCFGCGLNYHKRCASKIPNNCNGSKQRRPSAIPLSPSNSNILNLNERRQSRRDSCLEALDAARPSSTLGGAATPNIFITSDDCGDPVGGNFLQMPRKDRSCSWSGRPLWMEIAEATRVKIQVPHTFQVHSYKLPTVCQHCKKLLKGLLRQGMQCRGENETEKLQNGAVAKYCKYNCHKKCSEHVAKDCSGNTKASQFFLGTADDGVSEDRDDDLSLRSGSGGHKKAQNTPSAPLQGSEGSGSPGGAVVSFAQGLSNAPDDDVISSESANIPLMRVVMSKKQTKRKNNKLLKEGWIVHYTDQQNMRKKHYWRLDTKGITMYQDENTTRYYKEIPLNEILGVMTSSPEKSSEYLFEIRTGACVYFVYSSLTDEELYNIIHASPCIARKPSTVSSTDSGYLGSSGASSSCVRSREGSTVSSTITVDRTRRGGSTTSTENSEAESESSYSSFASIASTASKYLGRAADCLVLMTKRNGWSDAGSPADEKSSGSLDAQSWTTAIQSALMPVTPQSSVVGGKRVDKLKVPTEGETGHLGAKIQTEQEFSQLYQIFAEEVLGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDLLRAEVQILEQVDHPGVVHFMQMLETTDRIFVVMEKLKGDMLEMILSSEKGRLSERTTQFLVAQILEALRYLHHQNIVHCDLKPENILLNSNSDFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGFNRSLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAEFMYPPSPWKEISENAIEFINGLLQVKMSKRYTVAKAQSHIWMQNYTIWSDLRVLEKAVGQRFVTHESDDSRWHAYEKEHNVTPVYV
What is the function of this protein?
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC.  Acts in the intestine to regulate both innate immunity by promoting activation of pmk-1 and also stress response and life span by acting as an upstream, negative regulator of the daf-16 transcription factor (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase dkf-2, D kinase family-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Translocation to the cell membrane is required for kinase activation.