PharMolix/UniProtQA huggingface dataset:
Protein: CITE2_HUMAN
Sequence: MADHMMAMNHGRFPDGTNGLHHHPAHRMGMGQFPSPHHHQQQQPQHAFNALMGEHIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQKLNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGGSGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
What is the function of this protein?
Transcriptional coactivator of the p300/CBP-mediated transcription complex.  Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation.  Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex.  Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity.  Enhances estrogen-dependent transactivation mediated by estrogen receptors.  Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex.  Participates in sex determination and early gonad development by stimulating transcription activation of SRY.  Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm (LPM).  Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium (AGP); stimulates WT1-mediated transcription activation thereby up-regulating the nuclear hormone receptor NR5A1 promoter activity.  Associates with chromatin to the PITX2 P1 promoter region.
What are the official names of this protein?
Cbp/p300-interacting transactivator 2, MSG-related protein 1, MRG-1, P35srj.
What is the protein family that this protein belongs to?
Belongs to the CITED family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with EP300 in dot-like structures.
Protein: RS18_BUCCC
Sequence: MVRYFRRRKFCRFTAEGIKKIDYKDIMILKNYITENGKIVPSRITGTKAKYQRQLSRAIKIARFLGFIPYTDQHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y4555_KLEP3
Sequence: MYDNLKSLGITNPDEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYVIDELDQICQRDRTEIDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein KPK_4555.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: FMT_BACSU
Sequence: MTRIVFMGTPDFSVPVLRTLIEDGYEVVGVVTQPDRPKGRKKVLTPPPVKEEALRHGIPVLQPEKVRLTEEIEKVLALKPDLIVTAAFGQILPKELLDSPKYGCINVHASLLPELRGGAPIHYSILQGKKKTGITIMYMVEKLDAGDMISKVEVDIEETDNVGTLHDKLSVAGAKLLSETVPNVIAGSISPEKQDEEKATYAPNIKREQELLDWSRTGEELYNQIRGLNPWPVAYTTLNGQNLKIWASKKIAAPTTAEPGTVVAVEKEGIIVATGNETALLLTELQPAGKKRMKGEDFVRGAHVEAGDVLGVNNEKN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y1048_THEON
Sequence: MEVFGMAIITLVGEKLARPGVEFIYYGPAEPCRTCKLAGVCVGNLEPGRRYKILRVRSMPSHSCPLHEGKVRVVEVVEPSIEVAIEPRLAIAGSVIKLSFVDCSDPEKRDLFRPEGLFEGDSVKIIEILGDVECNGRTYKLVKVMRKKE
What are the official names of this protein?
UPF0179 protein TON_1048.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: ARGC_KARMG
Sequence: MIKIGIIGGAGYTANELIKILINHPKVEIKTIVSTTYPGIPIEYIHKDLIGEIKSNKLFSSEITDDIDLLFLCIGHGHSKKILKNISYKINVIDFSNDFRINKNFFFKKRIFNYGLPELNKNIINKYNNIANPGCFATAIQLSILPLAKIKLLKNNIHISAITGSTGAGRINNSKLNFSFRNNNISTYNLFNHNHINEVIQTINKLQNKYDGKIYFIPYRGGFSRGIISTLYTRIDLSFEEIKNIYDKFYKNDPFIFLSEKEIHLKQVINTNKCILNLKYIKNKLIITSIIDNLIKGASGQAVQNMNIMYNFEETCGLKLKPLGL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
Protein: Y613_PASMU
Sequence: MQILQKIKNITLTSLELIHVRLDMARIELVEQKNFLITLLSALFVIFILLLVSFISLLFGLNSLLDPETKQIVFFAISAGAFFLILILLLLMRKILKKQRNFMVDTLTEVKHDIQAIKGALGSPSSKDQE
What are the official names of this protein?
Uncharacterized protein PM0613.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOA_ECO24
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARSKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENPL_HUMAN
Sequence: MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity).  When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity).  Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092).  Has ATPase activity (By similarity).  May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059).
What are the official names of this protein?
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: INT2_CHICK
Sequence: MAECSGLQFVSPYAFEAMQKVDVVRLAALSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFLKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVKNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESVGGRRRTEALRHLCKMNPSQALRVRGMVVEECHLPGLGVALTLDHTKNESSDDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRDNISSVLWQMRRQLLLELMGILPTVRSTHIVEEADVDTEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTDEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVMWLSWMIKEEAYFESISGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTGSLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETTTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNVFQGLTGGENTRPAQRYSITTQLLVLYYVLSYEEALLANTKILAAMQRKPKSYSSALMDQIPIKYLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVEDWICEEQITGTDALLRRMLLTTIAKNHSPKQLQEAFSMLPGNHTQLMQILEHLTLLSAGELIPYAEVLTSNMNCLLNAGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSVKIVRQQKYTQNDLMIDPLIVLRCDQRVHRSPPLMDITLHMLNGYLLASKAYLNAHLKETAEQDIRPSQNNAMGPETPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKAQSSSTYSLLKSVQSTTSPKSSDVEEEEDSLLCNLREVQCLICCLLHQMYIADPNIVKLVHFQGYPCELLALTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSFLCIQYALPKSLSVARLAINVMGTLLTVLTQSKRYAFFMPTLPCLVSFCQAFPPLYEDIMSLLIQIGQVCASDVATQTRDFDPIITRLQQLKERPNEVSGLCKDSPYKSCSRDITSVDPDVQLCQCVESTIIEIINMSVSGV
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 2, Int2.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: NOP2_HUMAN
Sequence: MGRKLDPTKEKRGPGRKARKQKGAETELVRFLPAVSDENSKRLSSRARKRAAKRRLGSVEAPKTNKSPEAKPLPGKLPKGISAGAVQTAGKKGPQSLFNAPRGKKRPAPGSDEEEEEEDSEEDGMVNHGDLWGSEDDADTVDDYGADSNSEDEEEGEALLPIERAARKQKAREAAAGIQWSEEETEDEEEEKEVTPESGPPKVEEADGGLQINVDEEPFVLPPAGEMEQDAQAPDLQRVHKRIQDIVGILRDFGAQREEGRSRSEYLNRLKKDLAIYYSYGDFLLGKLMDLFPLSELVEFLEANEVPRPVTLRTNTLKTRRRDLAQALINRGVNLDPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQSQTGNSETATPTNVDLPQVIPKSENSSQPAKKAKGAAKTKQQLQKQQHPKKASFQKLNGISKGADSELSTVPSVTKTQASSSFQDSSQPAGKAEGIREPKVTGKLKQRSPKLQSSKKVAFLRQNAPPKGTDTQTPAVLSPSKTQATLKPKDHHQPLGRAKGVEKQQLPEQPFEKAAFQKQNDTPKGPQPPTVSPIRSSRPPPAKRKKSQSRGNSQLLLS
What is the function of this protein?
Involved in ribosomal large subunit assembly (PubMed:24120868).  S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable).  May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable).
What are the official names of this protein?
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase, Nucleolar protein 1, Nucleolar protein 2 homolog, Proliferating-cell nucleolar antigen p120, Proliferation-associated nucleolar protein p120.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RNPA_LACPL
Sequence: MRKSYRVKKETEFQQVFETRNSYANRQFVIYVLEKPGQPHFRVGISVGKKIGNAVARNWVKRRIRQSITELKPQLKQDADFLVIARPTVAGKSQAETKAYLSHALKLAHLLDND
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GCST_AERHH
Sequence: MIQTTVLHPKHLEAGAKMVDFHGWEMPINYGSQLEEHHQVRTDAGMFDVSHMTIVDLTGERVKAFLQHLLANDVAKLTVFGKALYSGMLTPEGGVIDDLITYYLGETFYRLVVNSATREKDLAWIRHHAQDFGVTVTERPELAMIAVQGSNAKAKAAKVFSAEQNAAVEGMKPFFGVQAGELFIATTGYTGEDGYEIVVPQEQACDLWQALLDNGVAPCGLGARDTLRLEAGMNLYGQDMDETVSPLAANMAWTIAWEPSDRQFIGRAALEAQKAAGSQPKLVGLVMEEKGVLRSGMPVTFTTAAGEEREGVITSGSFSPTLGYSIALARVPRDIGEQASVEIRKKLVTVKVTKPAFVRNGQKLV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: UVRC_ANAPZ
Sequence: MKNSNERLNDAFYALKKATCSVRKSVPGVYKMFGTEDRLLYVGKAKDLKKRLSSYLSINRMSVNVYTMVKQIVRLEITVTENETEALLLEAKLIKSLKPKYNIIMRDDKFYPYILFSKHKYPRIVLHREKRSEGRYTGLYGPFLSSVMTRHIIATIKKAFLLRSCPDNFFATRARPCIEYEIKNCSAPCMQKITEEDYAKAVQMAHKALTGQSKEIQCELFEMMCRFSNNQDYESAIVCRDRLHALKSMKECMGFQTGIHGDVDFIAVYKRQDLYCMQVVFFRDGVNYGSQPYFIESVGNASDADIVNMFMLQIYNDFPSVVYVDLPSDYDTNIMSTAIKQLMKREVDIRLPATRDELKAMGLARNYAMEALNRRVRNTAQDTDLEEFATFFDLLKAPERIEIYDNSHISGTHPYGVMVVCGKDGLLKKEYRKFKINTVTNGDDCSMMHEVISRRFKEIPDVLPDFILIDGGRGQRSAVYGELSRLGIPFACIAKGPGRVAGTEVFYFSNGEKLSLDPASKLMHFLCRLRDEAHRFAITSHRKSRDGKLQFSTLLNDIPGIGKTKGKAILAYFGSIQAMKHARVEEISKVPGISLKLAKRVADYLKESQTTLRA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_CYAP4
Sequence: MSYAQTRTQTKAGYKAGVQDYRLTYYTPDYTPKDTDILAAFRVTPQPGVPYEEAAAAVAAESSTGTWTTVWTDLLTDLDRYKGRCYDIEPVPGEDNQFIAYIAYPLDLFEEGSVTNLLTSLVGNVFGFKALKALRLEDLRIPVAYLKTFQGPPHGIQVERDKINKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKAQAETGEVKGHYLNVTAGTCEEMMKRAAFAKELEMPIIMHDFLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLSKCLRMSGGDHIHTGTVVGKLEGDKDITLGFIDLLRENYIEENRSRGIYFTQDWASMPGVMAVASGGIHVWHMPALVDIFGDDAVLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRNLMREGGDIIREACRWSPELAAACELWKEIKFEFEAVDTV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: SNAY5_LYCMC
Sequence: FILVVIALMVIEVKSDGYLMVRAGREKGCKVWCVINNTYCDKDCKLKGGSYGYCYFWKLACYCEGLPESSPDIWTYEKNTCST
What is the function of this protein?
Binds voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin LmNaTx34.5.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GGGPS_CALMQ
Sequence: MTVFESLMNKLTEKGALHFSLLDPDKVTMDKFIELAKGAEKAGSDALMIGGSYGVNEGTLDNYIDAVKQEVKLPIILFPGSVAGLSRRADAVLFLSVLNSTDPYYIIGAQVQAAVLMAKHYSNLESIPMAYIIVGEGGAVGFASYAKPIPFHMEDVIVAYALAAYYMGFSAIYLEAGSGAREPVPSSVVAKVKRAVRNKILMVGGGIKSPEAAYSIALAGADVIITGTVIEESPAVVLKDIVDAVHRGGLRRLSNSNENANAWVNDK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_CORGB
Sequence: MTSSRKVRPTKHIFVTGGVVSSLGKGLTAASLGQLLIARGLSVTMQKLDPYLNVDPGTMNPFEHGEVFVTEDGAETDLDLGHYERFLDRNLGLNANVTTGKVYSTVIAKERRGEYLGKTVQVIPHITDEIKARILSMGEPDAHGNAPDVVISEVGGTVGDIESQPFLEAARQVRHEIGRENCFFIHCSLVPYLATSGELKTKPTQHSVAELRGIGILPDALVLRCDREVPQGLKDKIAMMCDVDYEGVVSCPDSSSIYNIPDVLYREHLDTFIIRRLGLPFRDVDWSTWHDLLERVNNPRHELTVGIVGKYIDLPDAYLSVVEAVRAAGYANWTRTNIKWITSDDCETPSGAMKALSGLDAIVVPGGFGIRGIEGKIGAITFAREHKIPLLGLCLGLQCTVIEAARQAGLEQASSTEFDPAATQPVIATMEEQKAAVSGEADLGGTMRLGAYPATLEEGSLVAELYGTTEVSERHRHRYEVNNAYRAQIAEGSDLVFSGTSPDGHLVEFVEYPKEVHPYLVATQAHPEYKSRPTHAHPLFYGLVKTALELRVHP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CXCR1_MOUSE
Sequence: MAEAEYFIWTNPEGDFEKEFGNITGMLPTGDYFIPCKRVPITNRQALVVFYALVSLLSLLGNSLVMLVILYRRRTRSVMDVYVLNLAIADLLFSLTLPFLAVSKLKGWIFGTPLCKMVSLLKEFNFFSGILLLACISVDRYLAIVHATRTLARKRYLVKFVCVGIWGLSLILSLPFAIFRQAYKPFRSGTVCYEVLGEATTDFRMTLRGLSHIFGFLLPLLTMLVCYGLTLRMLFKTHMRQKHRAMGVIFAVVLVFLLCCLPYNLVLLSDTLLGAHLIEDTCERRNDIDQALYITEILGFSHSCLNPIIYAFVGQNFRHEFLKILANHGLVRKEVLTHRRVAFHTSLTAIY
What is the function of this protein?
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_GEODF
Sequence: MNKIDAIEMEQMKKNIPGFRPGDTVKVQVKIVEGDKSRIQAFQGVVIGRQNGGIRESFTVRKISNGVGVERSFPLHSPSIDAIEVITRGQVRRAKLYYLRKLRGKASRIKEKKYVAGM
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ILVH_MYCTU
Sequence: MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRGIGTAK
What is the function of this protein?
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
What are the official names of this protein?
Putative acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: TPIS_BUCCC
Sequence: MIKPIIVGNWKLNGSKKLIESFLKQLNQFLIKYYKICTVVIAPPVLYSHLIQNMFSSDKKNFFLGAQNIDIHFSGPFTGEISPIMLKDIGIKYVIIGHSERRLNHKETNEIIAKKFCMLKEENLVPILCIGETKKEKIDKKTKDICKKQIDIIFNMYGSNAFDNSIIAYEPIWSIGSGNSAAPKEVQCIAHFIRNYVKSKSNHNIENFFIQYGGSVTKNNAKELIYQKDIDGFLVGGASLQLEEFSKIIEITNI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_NITEC
Sequence: MESEKIIEERLKALRSTIALHDFHYYVQDAPIIPDADYDKLFRTLQQLEQQYPHLITPDSPTQRVGAPPLKVFARLTHQTPMLSLTNAFTEDEAIAFDKRIREALNVDQVNYAVEPKFDGLAVSLVYTNGILTNGATRGDGYTGEDITLNLRTIPSIPLRLQTATVTDQFEVRGEVVMLKADFEHLNEQQRNKGEKLFANPRNAAAGSLRQLDSNITAARKLTFFAYDAVLSHKDQPFFSKHSEILDYLKSQQFLVAQQNGTTTGVAGLLTYYHEMGALRLSLPYEIDGVVYKVDNLTQQETLGYVSRAPRFAIAHKFPAQEASTELLTIEIQVGRTGALTPVARLAPVFVGGVTVTNATLHNEDEVQRKQIMIGDTVIVRRAGDVIPEVVAVIPEQRPAHAQPFIMPDHCPVCGSKAARLPGEAVTRCTGGLYCPAQRKQAIWHFASRRALDIDGLGEKLIDQLIDRELVHTPADLYKLNIDTLASLERMAEKSARNLVTAIEHSKKTTLPRFIYALGIRHVGEATAKALANQASHLDQLMTLDIEQLQQIPDVGPIVAQSIIDFFSEAHNREVIRQLLDSGLQWEIPNHGVQQSEQTNSAVSGKTFVLTGTLPTMTRDQAKIKIEQQGGKVTGSVSSATSYVVAGSDPGSKYAKAIGLGISVLDEDQLLSLLQNISTGAQQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GLMS_BRUME
Sequence: MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAGEPLPGVIGIGHTRWATHGRPVEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFETETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAFLFEGDEELLIGARQGPPLAVGYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTNMLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGTAYYAATVAKYWFEQIARLPVDSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYCKAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTKAFTCQLSAMASLAIAAARARGAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEGALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGRIILITDKKGAESASIDTMATIVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.