PharMolix/UniProtQA huggingface dataset:
Protein: MDTD_ECOK1
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKLFRTRNFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMAFIIALPAFVFARVPSDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPB_SHEHH
Sequence: MSKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDEAFQEEFTDLLKNYAGRPTALTLTRNLSPNPLAKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGCYDKAHYLLGTAAGPHPYPTIVREFQRMIGAETKRQILEREGRLPDAVIACVGGGSNAIGMFADFIDEPEVALIGVEPAGKGIDTPMHGAPLHHGKTGIFFGMKAPLMQDSEGQVEESYSVSAGLDFPSVGPQHAHLAAIGRATYESATDDEALETFQLLARCEGIIPALESAHAIAYAVKLAKEATKETLLVVNLSGRGDKDIFTVADILEQQKVEQQKVEQQKADNQNTEKNNQESGNE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RL22_PIG
Sequence: MAPVKKLVAKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L22, Heparin-binding protein HBp15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3K_DICDI
Sequence: MENDQDQQQQQQQSQQQQPQQEEQEQVDVDLSSLQGQERIEYINTLIADSYNIAIAKKLEEFLDIQINENTYLFQANSTLLKLYQFNPTHLNKDSIAKMLAKALMNFPCNDFLFLSYMIPSIIQKEEPLLKLFILNNFLETCKFKEAWTHINSHSFFSEIPSFIDNIRNFISGVLSITYQNISITMLGELLNLSDRTQLVDYIQSKQPTWKISDSTVSLQSDNSKQKKADTFTFDQLSRILPTFIK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, Eukaryotic translation initiation factor 3 subunit 12, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ACIBT
Sequence: MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVYTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIREGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLNAASFYQIVQAFAQSK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFUB_TREPA
Sequence: MMIAERGVRASARGVLSLHHIGKTYPRVMPRSKRGVWGMFGHPGRRAVDDAHTAHGPCSGARETDAAEHSVLSDVNLSFFTGEIHALLGKNGAGKSTLAHILSGFCVPTHGQLRLDGKEQRFSVPFDALRAGIGIVHQQPVFAERATVFENVVMGSAALTGVRWVRRAQVRERIDRIIAQWRMPLKKEEYVACLSADKRFFVSLLCVLFRNPRFIILDEPRCAPAQSRAVFFSHLEEFFVRSSHAPRCGGGVIVVTHRFADALRWAQRISLIEGGKACSFLRTDLLDEYCSAHQVNECIQKVSCALMSASTVTSSAVSSFSSLSDTQSCATVPRTSSARPWVLRVESLQVSKHADVPLTDISFSVAASAIIGIVGTPEDGVHVLEDILCDMHAGASRTHCTGNILLQEHDQVWCLPLQRNTPSLLRAHGVACVPSNCIQRGASMQLTLFDLLVPYTLRTWRTRVRAQMRFVARLLAEEEIYCDPLQPACTLSGGQLQRVILARELATRPRLLILAEPAEGLDSASEQRLLARLRQVAQAGTALVLLAREQHQAQWRALCTERFLLRAGTLCAEVSGTPSPSQDSHT
What is the function of this protein?
Probably part of the ABC transporter complex RfuABCD involved in riboflavin import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable riboflavin import ATP-binding protein RfuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TTC6_HUMAN
Sequence: MMKYYDLAKFTIYQIAEMDKGLSELSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYASVI
What are the official names of this protein?
Tetratricopeptide repeat protein 6, TPR repeat protein 6.
Protein: TRHO_BURPS
Sequence: MTTVNLAAYRFVSLDSIEQWRPLVAARCNTLGLRGTILLAPEGINLFIAGPREATDAFVDYIRHDPLFEGKFADLPFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPSVDARTLKAWLDQGHDDASRPVVMLDTRNAFEVDVGTFDRALDYRIDKFSEFPAVIEANRADLEGKTIVSFCTGGIRCEKAAIHMKDVGIENVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLAPTADVTCFACRAVVPADAQQSPLYVPGKCCPACHPGDSGTPGRRAEPGAEPARAV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y443_VIBCM
Sequence: MAAVWREGDDLLLRLYIQPKASRDSIVGLHGEELKVAITAPPIDGKANAHLSKYLAKLCKVAKGSVVVEKGELGRHKQVRILQPSQIPAEIAALIE
What are the official names of this protein?
UPF0235 protein VCM66_0443.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: TBB2B_MOUSE
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.  Plays a critical role in proper axon guidance in both central and peripheral axon tracts.  Implicated in neuronal migration.
What are the official names of this protein?
Tubulin beta-2B chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL29_DESHD
Sequence: MKTKNFRDMTDEELLKEIDGFKTELFNLRFQLATGQLDNPARIREVRKGIARGKTILRERELKINRA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LSME2_HUMAN
Sequence: MPSLAPDCPLLAMPEETQEDSVAPMMPSQRSRGPLAPNHVHEVCLHQVESISDLHSGAGTLRPYLTEEARPWDELLGVLPPSLCAQAGCSPVYRRGGFLLLLALLVLTCLVLALLAVYLSVLQSESLRILAHTLRTQEETLLKLRLASLSQLRRLNSSEAQAPS
What are the official names of this protein?
Leucine-rich single-pass membrane protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UPPP_BUCA5
Sequence: MLDLHQVIVSIIIGVIEGITEFLPISSTGHMIIASHWLKIDNENTKILEIFIEFGSALSILYFFHKKILRILKFNINVKKTNTKNLHILLAILPTIFFGLLFYKKIKLLFNTYNVMYALILGGIFLLISEIFKPKKYKTCSINDISLLQSAIIGFFQIFCLYPGFSRSGATIGTAILLGIKRSVAIEFSFIISIPLIMGASFYDFINNMHNFKILDLPIFFIGFMISFIVSILCIKKLLKIINRTSLIFFGIYRFIISGLIYFIN
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DI3L1_XENTR
Sequence: MLKTEKILHLKARGRSVRAVREHYLREDVRCGSALCLTCPRDGKLLSEDLTHYVVPDCQILQDYLEVLEFPELRGIIIMQTACQSVQHQRGRRQYKRLCSLLRDTRHDCILFSNEFQNHAYLPREMGESALAWQTRCIYNSCVWYYQHCQKKIPVVMVTEDKSVIRQYNTETQEVYVVSFQIYLETFWPNLKGALELYKSLKETHRERELESREGNGKEYPEHLPLEILEAGIKSGRYQQGVLSVNKHRAQLEGFVRLQGLGGKETDIQSDILIYGTKPRNRAIHGDLVAVELLSRSEWKGRNGALCENETDEKAVDAQAEVMPTGRVVGILQRNWRDYVATFPAKEDIETQGKNAQRVLVMPWDYRIPKIRISTQQAEALQDYRVVVRIDSWESTSLYPNGHFVRVLGRTGNLEAEIATILVENSISVNPFSEAQLAEMPSNTPESPWQVKPEEGDRLDLRKTHLVFSIDPKGCEDVDDALSIRKLPSGHLELGVHIADVTHFVPPNTYTDIEARSRATTYYLADRRYDMLPLILSADLCSLLGGVDRYAVSVIWEMDSSTYEIRRVWYGRTIIRSSYKLSYEVAQQLMDGDLEPLNTEMELHPLKQDPVRLEQLLWAVGKLTEVAHATRMRRDMSGALELEGVEVRVQLGEKHSIDDLVPKQPLQMHETIAECMILANHWVAKKIWECYPQHALLRLHPPARQEFFQELKECAKARGFSIDTRSNKALADSLDQANDPSDPLVNQLLRMMATQAMSNARYFSTGSYTEDEFYHYGLALEKYTHFTSPIRRYADIVVHRLLLAAVNKGPKDNLLGNKDLEELCRHINVRNRAAQHCQKQSTELFQCMFFKDKDPDSDQRCISDAVIYGIRTNGVLLFLPRYGIKGAAYLKNIDGLVLACKDNGRCHWMPGSLQRLPDRIVVTTQEAKSFSYCLFDHVTVRIHVQSSRFHPDSIRLEIIRNRPHSSQEALPSASNPQLARSELVKEVTRTAVEAQLAVEGAEELKPVEHYQEYRQTQGQSLYSMLEELWDLALLDVSGA
What is the function of this protein?
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
What are the official names of this protein?
DIS3-like exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_LACP7
Sequence: MELWYTDQHTKDVRFSIKMKEQLVSVESEFQRIDIIETYEYGRVLVLDGEMMITEKDEFIYHEMITHVPMAVHPNIRNVLVIGAGDGGTIRELTKYDTIEHIDMVEVDKEIVQVCREYMPFTACKLNDKRVSMHFEEGLRFVRGKQDEYDLIIVDCADPFGPAEGLFTREFYGNCYKALHDDGILINQHESPFYNEHSGSVQKAHRHITAVFPLSTVYQCHIPSYPSGHWLFGFASKKYDPIKDLNDKKWNELKLPVRYYNTDLHKGCFYLPNYVKELLGSYE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_RAT
Sequence: MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALLAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Subunit of the 40S ribosomal complex (By similarity).
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_XANCB
Sequence: MSRHYEVVFLVHPDQSEQVPAMIERYKSLIEGGNGTIHRLEDWGRRQLAYPIQNLVKAHYVLLNIEVDQAVLSELVESFRFNDAVLRHLVIKRDGPDTEQSLIMKSKDEKGDKPERSERRRRDDEEVDAAPAATDTDGDNAEAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PDD2L_HUMAN
Sequence: MAAVLKPVLLGLRDAPVHGSPTGPGAWTASKLGGIPDALPTVAAPRPVCQRCGQPLALVVQVYCPLEGSPFHRLLHVFACACPGCSTGGARSWKVFRSQCLQVPEREAQDAQKQGNSLAAEDWCEGADDWGSDTEEGPSPQFTLDFGNDASSAKDVDWTARLQDLRLQDAVLGAAHPVPPGLPLFLPYYICVADEDDYRDFVNLDHAHSLLRDYQQREGIAMDQLLSQSLPNDGDEKYEKTIIKSGDQTFYKFMKRIAACQEQILRYSWSGEPLFLTCPTSEVTELPACSQCGGQRIFEFQLMPALVSMLKSANLGLSVEFGTILVYTCEKSCWPPNHQTPMEEFCIIQEDPDELLFK
What is the function of this protein?
Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
What are the official names of this protein?
Programmed cell death protein 2-like.
Protein: RSMA_STRPI
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDILKVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTNB_RAT
Sequence: MIEEGGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHATEISVSRLETVISSIYYQLNKRLPSTHQINVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYIFSQMSDSNGLMMFGKLDQFLKEALKLPTAVFEGPSFGYTEHAVRTCFPQQKKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCHCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKELSSWKSPAKKLSHAISKSLGCVPSREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYGQDMPNLLADEHALIASYVARLQHCTRVLDSPSRLDEEHRLIARYAARLAAEAGNMTRPPTDASFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKAQATGSPHTSPTHGGGRSMPMPVRSTSAGSTPTHGPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSGETQRFPLVSSSPSCPLPCPTIPTHSPSFHATFPSRNTRDLHPVPPSHMVSLY
What is the function of this protein?
Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids.  May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation.  May be required for proper maturation and function of a subset of inhibitory synapses.
What are the official names of this protein?
Dystrobrevin beta, DTN-B, Beta-dystrobrevin.
What is the protein family that this protein belongs to?
Belongs to the dystrophin family. Dystrobrevin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density. Cell projection, dendrite. Basal cell membrane. Postsynapse. Nucleus. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells.
Protein: MUTS_SHEB9
Sequence: MNVIDTDDLEKHTPMMRQYLTMKAEHHDMLLFYRMGDFYELFYDDAKRASELLGISLTARGKSGGDPIPMAGLPYHAVEGYLAKLVQIGQSVAICEQIGDPATSKGPVERKVVRIVTPGTLTDEALLQERQDNLLAAVYQGKIGFGYATLDVSSGRFVIAELDTRESLEAELQRTNPVEILYSEDFGELGLLNGFKGKRRRPEWEFDYDTSIKLLLTQFGTKDLHGFGIADARLSLQAAGCLMQYVKDTQRTALPHINAITRFNQTDSIVLDAATRRNLELTQNLAGGRDNTLAAVLDNTATPMGSRMLQRWIHQPLRDPKHIKARQQAVTELLDTTAHEGLHEQLKALGDIERIMARLALRTARPRDFARLRQALGLLPELQQSLSTLSAPHTTQLRQHIGEFPAEQALLERAIVDNPPMLIRDGGVIREGYNSELDEWRGLSEGASDYLVQLEAREKERTGINTLKVGYNRVHGYYIEVSRLQSSQVPLNYQRRQTLKNMERYITPELKEYEEKVLSSQGKALALEKQLWEQLFDLILPKLHELQAFARAAAELDVLSNFAERAETLGYTCPELSQDIGVQIEAGRHPVVERVSQTPFIANPVTLHNQRRMLIVTGPNMGGKSTYMRQVALITLMAHIGCFVPADRALIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILHNASASSLVLMDEIGRGTSTYDGLSLAWSAAEYLAQQVGAMTLFATHYFELTQLPELMAGVYNVHLDAIEHDDTIAFMHAVQEGAASKSYGLQVAALAGVPNKVIKAAKHKLQQLESRDHQAEGTRTPIQSLLALPEPVENPALTKLSNINPDNLTPKQALDLLYELKRLS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ACC1_CAEEL
Sequence: MSHPGWIMVSFLTELLSQSSKGIAQSLDNCANDTEIINALLKDSYNKHYIPSHPTHVRVDMWVQEVTSVSELTQDFEIDLYINEFWEDPALVYEDMNPCKRNISFDDKVLQRLWLPNTCFINSKSAAIHESPFKNVFLMVFSNGTLWTNYRMKLTGPCDMKLKRFPFDKQKCYLTFESFNYNTGEVRMQWNQPYPVILLKRIELPDFKLVNFSVIAVEQMYPAGWWDELTVAFVFERRYGWYVLQGYIPTMVTIVISWISFYLGPRAIPARTMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWMLSGMLFIFLSLLELAVVGFMSRNEGLPPKVKKRKRQEDDDEGFSWKSMQTSPHLELRQFWVDKRVNSLRNDSAVPPVEDYAPMELEQPYQNITKRREKRKWMSGLRKKWRAMRELRPETVDFYSAIFFPTAYMLFNISYWSFYLTSLSEYFDEDVNIDQP
What is the function of this protein?
Acetylcholine-gated chloride channel subunit.  Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits.  Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine.
What are the official names of this protein?
Acetylcholine-gated chloride channel subunit acc-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASTE_SERP5
Sequence: MFDLLALTLAGQVPAEQQGENANLHWRWLTEGLLEMTPKPGYRQAVVLSAGIHGNETAPIELLNQLVKDLLNGDRPLAVRLLVVLGNPAAMRAGKRYLHSDMNRMFGGRYRDFDHSGETARAQQLEQVIAEFFADEGAARFHYDLHTAIRDSRLPRFGILPFQTRPYSAEMLALLDAADLDALVIHSAPGGTFSHFTSEHAGAASCTLELGKARPFGVNDLQQFAAINRALQAAVSGEPLPLRSGSELRIFRVERSLIKRSEEFRLHLSDDTANFTELKQGTLLCDQPGEEYRVQHVSEWILFPNPGVALGLRAGMVLVEAPRSTLY
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: HFQ_AERHH
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPARAVNHHQHAPGAAGEEQGEAEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: NRFA_ECO5E
Sequence: MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSHDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGCADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TYW4_YARLI
Sequence: MNGVTNDKGHSDVTNTPESGISTPKKKNPKSDKPVKVKNPNNAASKAYTVDLKIQGTNNSSIVSKRSVERLYKEKHDLEFFRHFVKKPQRRSPIINRGYWTRMEAMGYCISAALAEKAPKHVIVNLGCGYDPYPFQHLHKHGLTENLIFVDVDYPDLMQIKVDTIRRSDELTKLVGEEKPAAEIKDKSVLMQTGNYIALSCDLRDLEKFEFIFRNLDLIVEGDNNPLILFTAEVSVTYMFQKDADNLLQWCASLPNSRFALLEQIIPAGTEHPFAKTMLAHFDSLQTTLWSVKKYPSIPAQYERFTCLGWKEVSGISLAQFWDSYVPDEKKEFVENVEAFDEWEEFLLFLNHYSIIYGGADIFQNSKSEYPEHEEFVLQCEKPTSEAHRIGAAACSFQNGVILNGGQAQNRESTSLLLSLDSTDEFIVDKNNMIARQYHSLSEIEPGVVLLAGGRSSPTKKFSDCHILKNGLWKPTFDLPEGRFRHCMQGTLLFGGSESKDQWLHFSPTAGWKALKCDFHYLTPYGATLIMKSPIEGILLGGMDAKGNLGKEVYSVTISEGETVVLSLIPMKSPLIYARYGAQGVYHGNRYLLVGGVSYDILFNEHNQVVELDIKKGNTIPVKLPFESYPLLVSHSVNIVRNCLVVAGGGAVCFSFGVFHSDPEVVGNRELKVIKEQRPSEEVKTEINSTVISVEEGTLESFPAAYVNATPTIFRNCDIGPSSELWKSHDYLKSNIGEDTKVSVHIADNKNLNFQSKNFSYQTLQFGELMKLISDIEADSESSKSAYLRSLSLDNPKSEATDLCKDFPGIARDFKLPKEMADFIGNKVFSTPLRISSSKTQIWLHYDVTANVLCQVTGSKRVRMYHPRDVVHLGFPAGESSSKIPNIFVHESCAQAYEVVMNPGDILFIPPMWLHAVEPQTESISVNCFWKDLDGNKYSKTKDIYGNKDLASYESGREGIKKIADKFAGLPADIKEFYLRRLAEELKQM
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 4, tRNA-yW synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: Y603_AQUAE
Sequence: MDTLAFINRALVEEGYSLKDIKLVLITDFEPSSVEAIRRLLAVNQGVSFIGRKYVKEVLEKFGLRNVRFRAVEEIPSLEFKLPESGTVKVLPFRNSPQEASAGYLLEEERILFSGKFLGSFGEKGDTIQIFHRVFFPCRNILDYNVGLLESIGEEFEVFPFYGEKQKLSAKTLKEYFNYTVKGSVLEREVILGLVNGVLLNLSDEERENLLSSIGYLAEVDDKVIVDFYTEPNLFYEEFVNTLPDAVKSKEEFYRIVEKLLEHNFYVPLRAV
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator aq_603.
Protein: MDH_ACIAC
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQKALKGVMMELEDCAFPLLAGMEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQIAAKTGGKVGEIEKLTVWGNHSPTMYADYRFATIGGKSVKDAINDQVWNADVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGSNGKWVTMGVPSKGEYGIPEGIVFGFPVITENGEYKIVEGLEIDAFSQERINKTLAELQGEQDGVKHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.