PharMolix/UniProtQA huggingface dataset:
Protein: CP7A1_RAT
Sequence: MMTISLIWGIAVLVSCCIWFIVGIRRRKAGEPPLENGLIPYLGCALKFGSNPLEFLRANQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPNDGNTTENINNTFTKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSNAWVTEGMYAFCYRVMFEAGYLTLFGRDISKTDTQKALILNNLDNFKQFDQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLAILWASQANTIPATFWSLFQMIRSPEAMKAASEEVSGALQSAGQELSSGGSAIYLDQVQLNDLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDMIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYSNGNKLKCFYMPFGSGATICPGRLFAVQEIKQFLILMLSCFELEFVESQVKCPPLDQSRAGLGILPPLHDIEFKYKLKH
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (PubMed:1694852, PubMed:2335522).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:1694852, PubMed:2335522).  Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis.  Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting step in cholesterol catabolism and bile acid biosynthesis (PubMed:1694852, PubMed:2335522).  7-alpha hydroxylates several oxysterols, including 4beta-hydroxycholesterol and 24-hydroxycholesterol.  Catalyzes the oxidation of the 7,8 double bond of 7-dehydrocholesterol and lathosterol with direct and predominant formation of the 7-keto derivatives (By similarity).
What are the official names of this protein?
Cytochrome P450 7A1, 24-hydroxycholesterol 7-alpha-hydroxylase, CYPVII, Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single- pass membrane protein.
Protein: CC172_MOUSE
Sequence: MSLESLFQHIIFSEHQAEESRRVMREVRSEITRCRGKIKKATEDLSEEKIKLESKVQQLSEKSFLLELLKTHENALERQLSEIISERDTLLQACEAIKNKTTEEEERFIKEITDFNDNYEITKKRDTLMKENIEMEMADLDSQADVLRREMKSVERNRGQLWELQKLKNELLQELFTLQKKLKVLKDEETEAICITKQLEAEKTKVRDKPQHDPECVRLKRELDLYKAEDMESVYRALQAEVDLLELALAPKDPQDSNSLSHEPPHT
What are the official names of this protein?
Coiled-coil domain-containing protein 172, TEKT2-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the CCDC172 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Note=In caput spermatozoa, localized in the middle piece, predominantly concentrated at the mitochondrial sheath of the flagella and to a lesser extent with outer dense fibers (ODF) (By similarity). Colocalized with TEKT2 at the perinuclear region (PubMed:24394471).
Protein: UPPP_SHIBS
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_PSEFS
Sequence: MSDLSHIRNFSIIAHIDHGKSTLADRFIQMCGGLAEREMEAQVLDSMDLERERGITIKAHSVTLYYTAKDGIKYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKIDLPQADPDRVKEEIEKIIGIDATDAVECSAKTGLGVDEVLERLVKTIPAPTGNYEDPLQALIIDSWFDNYLGVVSLVRVRHGRVKKGDKILVKSTGKIHLVDSVGVFNPKHTATTDLKAGEVGFIIAGIKDIHGAPVGDTLTLSSTPDVDVLPGFKRIQPQVYAGLFPVSSDDFEDFREALQKLTLNDSSLQYTPESSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVIFELALKTGETIYVDNPSKLPDLSSIEDMREPIVRANILVPQEHLGNVITLCIEKRGVQHDMLFLGTQVQVTYDLPMNEVVLDFFDRLKSTSRGYASLDYHFDRYQSANLVKLDVLINGDKVDALALIVHKDNAHYKGRQLTEKMKELIPRQMFDVAIQAAIGGQIIARTSVKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKQVGNVEIPQEAFLAVLRLDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROC_EDWI9
Sequence: MAGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARREADRVRILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRMGDIVCRQYDWAQVEQNPFFCPDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAVKGVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMVPGQTITRAGEATTIVTHGRHDPCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: YGDI_ECOL6
Sequence: MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTDNDTGMISYKDANGNKQQINRTDVKEMVELDQ
What are the official names of this protein?
Uncharacterized lipoprotein YgdI.
What is the protein family that this protein belongs to?
To E.coli YgdR.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CISY_RICCN
Sequence: MTNENNNDSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMIKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPFLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPRQLYTGYVHREYKGIRER
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: SPEH_METM6
Sequence: MKQLGKHIILELWGCENQALDDQPGIEKMLVDAVKACGATLICVKTHKFSPQGVTGVAVLSESHISIHTWPELRYAAMDVFTCGEHVTPHDTIPEIQKFLKPEKIDVMDIKRGIIEVDEVKE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: SYI_STRMK
Sequence: MSQDYKTTLNLPATEFPMRGDLPKREPGILARWEAQGLYQQLRDNAAGRPLFVLHDGPPYANGRIHLGHAVNKILKDIIVKSRYLAGFDAPYVPGWDCHGLPIEIAVEKKWGKVGTKLDAVEFRQKCREFAEEQINIQRVDFKRLGVTGDWDNPYKTLSFDFEANEIRALSKVVANGHLVRGAKPVYWCFDCGSALAEAEIEYQEKESPAIDVAYAARDAQAIGQAFGVSVPADVEVAVPIWTTTPWTLPASLAVSLGAEITYVLAEGPAHNGKRRWLVLAAALAERALQRYGVENLVLHGETTGAALENQLLAHPFYPEREILVLNGDHVSDEDGTGAVHTAPGHGQEDFVVSQKYGLLDKYNAGQVTPIDGRGVYLESTPPAGDVVLAGQHLWKAQEAIVGVLRDNGSLLAFHPIRHSYPHCWRHKTPVVFRATPQWFISMDKANLRNDALAAIDTVGWFPTWGKARIQSMVDGRPDWTISRQRTWGVPIALFTHRQTGEIHPRSVELMQQVADRVEAEGIDVWYSLDATELLGAEAADYEKVTDILDVWFDSGVTHEGVLAARGFGKPADLYLEGSDQHRGWFQSSLLTGVAIDKRAPYKQCLTHGFTVDEHGRKMSKSLGNGIEPQDIMNKLGADILRLWIASADYSNEMSLSQEILKRNADAYRRLRNTARFLLGNLDGFDPAQHLRPLDQMVALDRWIVHRAWELQEKIKAAYDGYNMAEIVQLLLNFCSVDLGSLYLDVTKDRLYTMPTDSHGRRSAQSAMYHIAEAFTRWVAPILTFTADELWGYLPGEHAGHVLFTTWYDGLAPLPADAQLNATDFDQLLAVREQVAKVLEPMRANGAIGAALEAEITIAANEEQAAKWQPLADELRFLFISGDVQVRPATTDEVFVSAQPTTKAKCVRCWHHRADVGRNADHPELCGRCVSNVTGAGEVRSWF
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_MARMS
Sequence: MTVINMKDVDLANKRVLIREDLNVPVKDGKVTSDARIRAALPTIKMALEAGAKVMVMSHLGRPTEGQYEEEYSLQPVATHIAGLLGQDVPLVKDWLDGVEVESGQLVLVENVRFNLGEKKDDEALSKKMAALCDVFVMDAFGTAHRAQASTHGVAKFAPIACAGPLLSAELEALEKALAKPARPMAAIVGGSKVSTKLTVLESLSDKVDQLIVGGGIANTFLAAAGFPVGKSLYEEDLIPQAKALMAKTSIPLPEDVVVATAFAPDAVATVKDAADVGPDDMILDIGPKAAAAFAALLEESQTIIWNGPVGVFEFDQFGGGTKALAMAIANSKGFSIAGGGDTLAAVDKYDIADQVSYISTGGGAFLEFVEGKVLPAVAMLESRAQN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSAA_BACSU
Sequence: MSIYHMKVRTITGKDMTLQPFAGKVLMIVNTASKCGFTSQLKQLQELYDTYQQEGLEILGFPCNQFMNQEPGEEADIQEFCETNYGVTFPMFSKVDVNGKNAHPLFVYLTEHAKGMLGTKAIKWNFTKFIVDRNGEIVGRYSPNTNPKELEDDIVKLLEQ
What are the official names of this protein?
Glutathione peroxidase homolog BsaA.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: PKWA_THECU
Sequence: MIEPLQPGDPGRIGPYRLVSRLGAGGMGQVFLARSPGGRPVVVKVILPEYANDDEYRIRFAREVEAARRVGGFHTAQVIDADPTADPPWMATAYIPGPSLRKAVTERGPLYGNNLRTLAAGLVEGLAAIHACGLVHRDFKPSNIVLAADGPRVIDFGVARPLDSSVMTQSGAVIGTLAYMSPEQTDGSQVGPASDVFSLGTVLAFAATGRSPFMADSIGEIIARISGPPPELPELPDDLRELVYACWEQNPDLRPTTAELLAQLSTDHTGDDWPPPHLSDLIGSMLPLGATTSPNPSLAIEPPPPSHGPPRPSEPLPDPGDDADEPSAEKPSRTLPEPEPPELEEKPIQVIHEPERPAPTPPRPREPARGAIKPKNPRPAAPQPPWSPPRVQPPRWKQLITKKPVAGILTAVATAGLVVSFLVWQWTLPETPLRPDSSTAPSESADPHELNEPRILTTDREAVAVAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSDSTVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASEDGTIRIWPIATE
What is the function of this protein?
May play a regulatory role during the complex growth cycle and in secondary metabolite production.
What are the official names of this protein?
Probable serine/threonine-protein kinase PkwA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SULA_EDWTE
Sequence: MRTSPLHPATDSVVFSRPACQSAPTVPQSGFVSELGYGAQQPLLSLLLPPLLRQLGEQSRWQLWITAQHKPSKRWLSACGVPVHKVMQLRRAEAGEAIYAMEQALRSGNYSVVLGWLPPLTAAERLRLNRAAQAGRSIGLLMQPQEGKLAAAAPPQAHAANRGSARYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity).
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: RL18E_METTH
Sequence: MVRKITKTNPNLIKLIRNLRKKSSQEGAAIWKDVARRLERPTRNRAAVNISKINRHSDEDETVLVPGKVLGSGNLDHRVQVVALSFSQTARDKIERAGGECLTLGKIVEENPAIKNIKIIE
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: SSY1_ORYSI
Sequence: MATAAGMGIGAACLVAPQVRPGRRLRLQRVRRRCVAELSRDGGSAQRPLAPAPLVKQPVLPTFLVPTSTPPAPTQSPAPAPTPPPLPDSGVGEIEPDLEGLTEDSIDKTIFVASEQESEIMDVKEQAQAKVTRSVVFVTGEASPYAKSGGLGDVCGSLPIALALRGHRVMVVMPRYMNGALNKNFANAFYTEKHIKIPCFGGEHEVTFFHEYRDSVDWVFVDHPSYHRPGNLYGDNFGAFGDNQFRYTLLCYAACEAPLILELGGYIYGQKCMFVVNDWHASLVPVLLAAKYRPYGVYRDARSVLVIHNLAHQGVEPASTYPDLGLPPEWYGALEWVFPEWARRHALDKGEAVNFLKGAVVTADRIVTVSQGYSWEVTTAEGGQGLNELLSSRKSVLNGIVNGIDINDWNPSTDKFLPYHYSVDDLSGKAKCKAELQEELGLPIRPDVPLIGFIGRLDYQKGIDLIKLAIPDLMRDNIQFVMLGSGDPGFEGWMRSTESGYRDKFRGWVGFSVPVSHRITAGCDILLMPSRFEPCGLNQLYAMQYGTVPVVHGTGGLRDTVENFNPFAEKGEQGTGWAFSPLTIEKMLWALRMAISTYREHKSSWEGLMKRGMSSDFTWDHAASQYEQIFEWAFMDQPYVM
What are the official names of this protein?
Soluble starch synthase 1, chloroplastic/amyloplastic, SSS 1, Starch synthase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, soluble.
Protein: PCMB_XANP2
Sequence: MIHAGTRPLRVLVTKIGLDGHDRGSRIVAAYLRDAGMEVIYTPPWQTIPGVVKLATEEDVDVIGISSLATDHLIVPKMMEALRAAGLGHVGVVVGGIVPEAEQSALAAAGVSRVFGPGAAREEIVECVTALGQKSRAERVDDYSEANP
What is the function of this protein?
Together with Xaut_5043, catalyzes the reversible isomerization between pivalyl-CoA and isovaleryl-CoA, using radical chemistry.  Does not exhibit isobutyryl-CoA mutase (ICM) activity.
What are the official names of this protein?
Pivalyl-CoA mutase small subunit, PCM small subunit, Pivalyl-CoA mutase, AdoCbl-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA mutase small subunit family.
Protein: CEL2A_BOVIN
Sequence: MIRALLLSTLVAGALSCGVPTYPPQLSRVVGGEDARPNSWPWQVSLQYSSSGQWRHTCGGSLIEQNWVLTAAHCISSSRTYRVVVGRQSLSTVESGSLTIAVSKSVIHEKWNSNQLAQGNDIALLKLASSVPLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQSNGALPDILQQGKLLVVDYATCSNPSWWGSTVKTNMICAGGDGVTSSCNGDSGGPLNCQAANRQWQVHGIVSFGSSLGCNYYRKPSVFTRVSNYNDWISSVIENN
What is the function of this protein?
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism.  Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity.
What are the official names of this protein?
Chymotrypsin-like elastase family member 2A, Elastase II, Elastase-2, Elastase-2A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDC_MYCTO
Sequence: MTPQKSDACSDPVYTVGDYLLDRLAELGVSEIFGVPGDYNLQFLDHIVAHPTIRWVGSANELNAGYAADGYGRLRGMSAVVTTFGVGELSVTNAIAGSYAEHVPVVHIVGGPTKDAQGTRRALHHSLGDGDFEHFLRISREITCAQANLMPATAGREIDRVLSEVREQKRPGYILLSSDVARFPTEPPAAPLPRYPGGTSPRALSLFTKAAIELIADHQLTVLADLLVHRLQAVKELEALLAADVVPHATLMWGKSLLDESSPNFLGIYAGAASAERVRAAIEGAPVLVTAGVVFTNMVSGFFSQRIDPARTIDIGQYQSSVADQVFAPLEMSAALQALATILTGRGISSPPVVPPPAEPPPAMPARDEPLTQQMVWDRVCSALTPGNVVLADQGTSFYGMADHRLPQGVTFIGQPLWGSIGYTLPAAVGAAVAHPDRRTVLLIGDGAAQLTVQELGTFSREGLSPVIVVVNNDGYTVERAIHGETAPYNDIVSWNWTELPSALGVTNHLAFRAQTYGQLDDALTVAAARRDRMVLVEVVLPRLEIPRLLGQLVGSMAPQ
What is the function of this protein?
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
What are the official names of this protein?
Alpha-keto-acid decarboxylase, KDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: YCF12_STIHE
Sequence: MNNLEVVFQLMALFFVLAAGPAVVVLVASQKGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLMU_LACDB
Sequence: MEKYVVVLAAGKGTRMKTKLYKVLHQVCGKAMVEHVVDAARAVKPSKIVTIVGHGAEDVEKVLAGKSEFVMQEEQLGTGHAVMQAEGQLAALEGATLVVTGDTPLFTSETFEKLFAYHEEEGNAATVLTAEAPDPFGYGRIIRDDQGNVLRIVEQKDGKPEELKVKEINTGVFCFDNQDLWVALKQVGNDNSQGEYYLTDVLEILRKAGKKVGAYKMPDFSESLGVNDRIALAEATRIMQRRINEGHMRDGVTFIDPATAYIDADVEIGNDTVIEGGVTIKGHTVIGSDCLITSGSRIVDSQIGNGVTVTSSTIEESIMEDNTDIGPNSHLRPKALIKRGAHLGNFVEVKKAEIGENTKVGHLTYVGDATLGKDINVGCGVIFSNFDGVKKFHTTVGDKSFIGAGSTLVSPINVADHAFIAADSTITKDVGKYEMAIARGRQVNKKDYWHKLPLSEDEEWK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP10_YEAST
Sequence: MHLMYTLGPDGKRIYTLKKVTESGEITKSAHPARFSPDDKYSRQRVTLKKRFGLVPGQ
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis (PubMed:9843512).  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (PubMed:9843512).  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (PubMed:9843512).  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs (PubMed:21131909).  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA (PubMed:21131909).  Essential for growth (PubMed:9843512).
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit NOP10, Nucleolar protein 10, Nucleolar protein family A member 3, snoRNP protein NOP10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FACR1_RAT
Sequence: MVSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRLRDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVGDYLNHSFKTNPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY
What is the function of this protein?
Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols.  It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols.  In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
What are the official names of this protein?
Fatty acyl-CoA reductase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: GAG_EIAVY
Sequence: MGDPLTWSKALKKLEKVTVQGSQKLTTGNCNWALSLVDLFHDTNFVKEKDWQLRDVIPLLEDVTQTLSGQEREAFERTWWAISAVKMGLQINNVVDGKASFQLLRAKYEKKTANKKQSEPSEEYPIMIDGAGNRNFRPLTPRGYTTWVNTIQTNGLLNEASQNLFGILSVDCTSEEMNAFLDVVPGQAGQKQILLDAIDKIADDWDNRHPLPNAPLVAPPQGPIPMTARFIRGLGVPRERQMEPAFDQFRQTYRQWIIEAMSEGIKVMIGKPKAQNIRQGAKEPYPEFVDRLLSQIKSEGHPQEISKFLTDTLTIQNANEECRNAMRHLRPEDTLEEKMYACRDIGTTKQKMMLLAKALQTGLAGPFKGGALKGGPLKAAQTCYNCGKPGHLSSQCRAPKVCFKCKQPGHFSKQCRSVPKNGKQGAQGRPQKQTFPIQQKSQHNKSVVQETPQTQNLYPDLSEIKKEYNVKEKDQVEDLNLDSLWE
What is the function of this protein?
p9 plays a role in budding of the assembled particle by interacting with PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein.
What is the protein family that this protein belongs to?
Belongs to the equine lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: PRNA_PSEFL
Sequence: MNKPIKNIVIVGGGTAGWMAASYLVRALQQQANITLIESAAIPRIGVGEATIPSLQKVFFDFLGIPEREWMPQVNGAFKAAIKFVNWRKSPDPSRDDHFYHLFGNVPNCDGVPLTHYWLRKREQGFQQPMEYACYPQPGALDGKLAPCLSDGTRQMSHAWHFDAHLVADFLKRWAVERGVNRVVDEVVDVRLNNRGYISNLLTKEGRTLEADLFIDCSGMRGLLINQALKEPFIDMSDYLLCDSAVASAVPNDDARDGVEPYTSSIAMNSGWTWKIPMLGRFGSGYVFSSHFTSRDQATADFLKLWGLSDNQPLNQIKFRVGRNKRAWVNNCVSIGLSSCFLEPLESTGIYFIYAALYQLVKHFPDTSFDPRLSDAFNAEIVHMFDDCRDFVQAHYFTTSRDDTPFWLANRHDLRLSDAIKEKVQRYKAGLPLTTTSFDDSTYYETFDYEFKNFWLNGNYYCIFAGLGMLPDRSLPLLQHRPESIEKAEAMFASIRREAERLRTSLPTNYDYLRSLRDGDAGLSRGQRGPKLAAQESL
What is the function of this protein?
Involved in the biosynthesis of the antifungal antibiotic pyrrolnitrin.  Catalyzes the chlorination of tryptophan (Trp) at C7 position to yield 7-chloro-L-tryptophan (7-CLT).  The reaction between FADH2, Cl-, and O2 generates the powerful oxidant HOCl, which is presumed to carry out the chlorination reaction.  The reaction of HOCl with the active site Lys-79 generates a lysine chloramine, which plays a key role in directing regiospecific chlorination of substrate in this important class of biosynthetic enzymes.  It is also able to use bromide ions to generate monobrominated Trp.
What are the official names of this protein?
Flavin-dependent tryptophan halogenase PrnA.
What is the protein family that this protein belongs to?
Belongs to the flavin-dependent halogenase family. Bacterial tryptophan halogenase subfamily.
Protein: KCA10_MOUSE
Sequence: MDVCSWKEMEVALVNFDNSDEIHEEPGYATDFDPTSSKGRPGSSPFSNWRVLISDNTNHETAFSKIPGEYVDPPGPEPVVLNEGNQRVIINIAGLRFETQLRTLNQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDFHRQFWLLFEYPESSSAARGVAVVSVLVVVISITIFCLETLPEFREDRELKVVRDPSINTNKTGLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFFKNIMNIIDIISIIPYFATLITELVQETEPSAQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKPNIPGELDKILNSMGSRMGSTESLNKTNGSCSAEKSRK
What is the function of this protein?
Mediates voltage-dependent potassium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.  The channel activity is up-regulated by cAMP.
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 10, Voltage-gated potassium channel subunit Kv1.8.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.8/KCNA10 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.