PharMolix/UniProtQA huggingface dataset:
Protein: Y027_MYCTU
Sequence: MTDRIHVQPAHLRQAAAHHQQTADYLRTVPSSHDAIRESLDSLGPIFSELRDTGRELLELRKQCYQQQADNHADIAQNLRTSAAMWEQHERAASRSLGNIIDGSR
What are the official names of this protein?
Uncharacterized protein Rv0027.
Protein: SYFA_BART1
Sequence: MSDIERLEQEICLALEAANDEQALEAVRIAALGKKGSISEKLKALGKMEASERQKAGPVLNGLKNRILELWAQKRDLLKRQAMDTRLSRETVDITLPVRSSPMERGRIHPISQVIEEIIAIYTKMGFSLAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFDVDKIGERKLLRTHTSPVQIRTLEKQKAPIRIIIPGKTYRMDSDATHSPMFHQVEGLVIDKTSTIAHMMWLHETFCKEFFEVASVKMRFRPSFFPFTEPSMEVDIQCDRSGSEVKFGEGQDWLEILGCGMVHPHVLKNVGLDPDEYQGFAWGMGIDRIAMLKYGMPDLRAFFDADLRWLDHYGFRCFDMPAFFPNRNV
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SHESH
Sequence: MIALIQRVTQAKVDVDGKTIGAIDKGLLVLLGVEREDDSFKMEKLANKVMSYRVFSDENGKMNLNVSQAGGALLVVSQFTLAADTGRGLRPSFSGAGTPDQAKVLYEEFVAFCRAKGMPTQTGEFAADMQVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_YERE8
Sequence: MNNTDKLDSHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYSDAKRASQLLDISLTKRGASAGEPIPMAGVPYHSIENYLAKLVQLGESAAICEQIGDPATSKGPVERKVVRIVTPGTVSDEALLQERQDNLLAAIWQDARGFGYATLDISSGRFRVAEPADLETMAAELQRTNPAELLYPENFEQMSLIEHRHGLRRRPLWEFELETAKQQLNLQFGTRDLIGFGVEQAHQALRAAGCLLQYVKDTQRTSLPHIRGLTMERQQDGIVMDAATRRNLELTQNLSGGTENTLAAILDCTVTAMGSRMLKRWLHMPIRDTKVLTDRQQAIGGLQDITAELQTPLRQVGDLERILARLALRTARPRDLARMRHAFQQLPEIHRLLQPVNVPHIQNLLSQVGQFDELQDLLERAIVETPPVLVRDGGVIASGYNAELDEWRALADGATDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALAIEKGLYEEIFDLLLPHLPELQTSANALAELDVLANLAERAETLNYNCPVLSDKPGIKITGGRHPVVEQVLSEPFISNPLTLSPQRRMLIITGPNMGGKSTYMRQTALIVLLAHMGSYVPADQATIGPVDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEQSLVLMDEIGRGTSTYDGLSLAWACAENLASRIKAMTLFATHYFELTTLPEKMEGVVNVHLDALEHGETIAFMHSVQDGAASKSYGLAVAALAGVPRDVIKRARQKLKELESLSNNAAASKIDGSQLTLLNEEVSPAVEALEALDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: B277_SSV1
Sequence: MSDGKLLSAFEEELRKAQSLEELKQKYEEAQKQIADGKVLKRLYKVYEKRQTELMLQQYRQIKAELEKRKKVKKKDKADIRVRVVKKWINSRLFSAEHYVALLQENQDGLSILFLRRAKLIENQGYLMLEVKKLRKAWVLTAEPILLERLKFPFGKKFVAVHFVLPNYPYTLQLKPDEKLKELAVKAINGPQIMSAMIRTKFFEALARVGSGPDLMMLIIGVVMGIGIGVAIGFGIANANLTHLLSQHVTNTTVTHTTTTTTSPSFTIPSNSSKGVS
What is the function of this protein?
This protein may be involved in virus assembly.  Essential for virus function.
What are the official names of this protein?
Uncharacterized protein B-277.
Protein: ATPA_XYLFM
Sequence: MATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNKTYALALNLERDSVGAVILGDYKHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGKGTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTAMAIDTVISQKDTGIKCVYVAIGQKASTIANIVRKLEENDALDHTIVVAATASESAALQYISAYAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTQGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDETTRKQLERGQRVTELMKQKQYTSMSVANQALSIYAVNEGYLDDIPVDKVLTFEEGLHAHFSNTQGALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMJ_ECOL6
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_HAEIG
Sequence: MKQLLDFIPLILFFITYKLGGVREAAIVLVVATILQIVILKWKYGMVEKQQKIMASAVVFFGLLTAYFNEIRYLQWKVTIINGLFAIVLLVAQFQFKTPLIKKLLGKELQLPEKAWNTLNLGWALFFIICMLVNIYISHNMSEEAWVDFKSFGIIGMTVIATIISGVYIYRYLPKDGSNSKDGEK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL31_THEYD
Sequence: MKEKIHPEYKEAKVVCACGETFVTRSTKPVIKVDICSKCHPFYTGKQKIVDTEGRVEKFMKKYSKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PCKG_CORGL
Sequence: MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDVARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMTRMGIEALDKIGANGSFVRCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVMAREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGVAPGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWMGNDWTPESDENAAHPNSRYCVAIDQSPAAAPEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQNWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGHVGADETVVGHTAKAEDLDLDGLDTPIEDVKEALTAPAEQWANDVEDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK, GTP-dependent phosphoenolpyruvate carboxykinase, GTP-PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRB_BASAL
Sequence: KIMAKPSKFYEQLRGR
What is the function of this protein?
Possesses antifungal activity against B. cinerea, M. arachidicola and F. oxysporum but not C. comatus and R. solani.  Inhibits HIV-1 reverse transcriptase and cell-free translation.
What are the official names of this protein?
Beta-basrubin.
Protein: SOX5_MOUSE
Sequence: MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQETCGPRTPTVQHNTMEVDGNKVMSSLSPYNSSTSPQKAEEGGRQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGLPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGKVAVVNSIGLSNCRTEKEKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPSAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGAKGEEPHIKEEIQAEDINGEIYEEYDEEEEDPDVDYGSDSENHIAGQAN
What is the function of this protein?
Transcription factor involved in chondrocytes differentiation and cartilage formation (PubMed:1396566, PubMed:11702786, PubMed:8078769, PubMed:15529345, PubMed:14993235).  Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes, such as COL2A1 and AGC1 (PubMed:9755172, PubMed:11702786, PubMed:26150426).  Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate (PubMed:11702786, PubMed:15529345, PubMed:14993235, PubMed:26150426).  Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (PubMed:14993235).  Together with SOX6, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (PubMed:14993235).  Binds to the proximal promoter region of the myelin protein MPZ gene (PubMed:26525805).
What are the official names of this protein?
Transcription factor SOX-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_YERPE
Sequence: MATKPQDANTTSREAITSKADSPPRPTALIFDSGVGGLSVYQEIRQLLPDLHYIYAFDNVAFPYGEKSGEFIVERVLEIVTAVQQRHPLAIVVIACNTASTVSLPALRERFAFPVVGVVPAIKPAVRLTRNGVVGLLATRATVHASYTLDLIARFATDCKIELLGSSELVEVAETKLHGGVVPLEVLKKILHPWLSMREPPDTIVLGCTHFPLLTEELAQVLPEGTRMVDSGAAIARRTAWLISSQENVISSQDENIAYCMALDEDTDALLPVLQSYGFPKLQKLPI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: GDIA_MOUSE
Sequence: MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILEGPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKDIYKRMAGSAFDFENMKRKQNDVFGEADQ
What is the function of this protein?
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.  Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation.  Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
What are the official names of this protein?
Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans- Golgi network.
Protein: PSB_MYCA9
Sequence: MIWRDDAIASQPAGQHFRNSHLSSFSEYLRAQAPELLPALGKASADVIGNLPHGTTIVALTYRGGVLIAGDRRATQGNYIANRDIDKVQITDNYSATGIAGTAAIAVEFARLYAVELEHYEKLEGVQLTFNGKANRLSALVRGNLAAAMQGLVAVPLLVGYDLDDPNGETAGRIVSFDVAGGWHVESDGYQAVGSGSVFAKSSIKKLYRPGGDALTALAVAVEALYDAADDDSATGGPDLVRRVFPTAIRIDSGGAVRVPEADIERIAREVIAKRTEAAREEADLRESGGDS
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB34_RAT
Sequence: MNILAPVRRDRVLAELPQCLKKEAALHVRKDFHPRVTCACQEHRTGTVGFKISKVIVVGDLSVGKTCLINRFCKDTFDKNYKATIGVDFEMERFEVLGVPFSLQLWDTAGQERFKCIASTYYRGAQAIIIVFNLNDVASLEHSKQWLADALKENDPSNVLLFLVGSKKDLSTPAQYSLMEKDALKVAQEIKAEYWSVSSLTGENVREFFFRVAALTFEANVLAELEKSGSRHIGDVVRINSDDKNLYLTASKKKATCCP
What is the function of this protein?
Transport protein involved in the redistribution of lysosomes to the peri-Golgi region (By similarity).  Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis.  Plays a role in the fusion of phagosomes with lysosomes (By similarity).  Acts also as a positive regulator of hedgehog signaling and regulates ciliary function (By similarity).
What are the official names of this protein?
Ras-related protein Rab-34.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, cilium. Note=Recruited to phagosomes containing S.aureus or Mycobacterium.
Protein: QUEF_STRR6
Sequence: MQHYETVEAVTFAYGQHHHLEIQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLAEQRLFQHDLYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
Putative NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2N_ORYSJ
Sequence: MSTLVTCSLPGAVTTHASTRRFGGSQFQTSQASCISFKREVSAKAVLRSVRCNATQTQSAQRKSSTATVKRSDPKGKTQGPKLDDGSGGFPPFRFGKGGGGGGGGGGGSNYFGGFLLFTCVLLLDYLKEFEKNLIARRQRAGYDANNDMFQQ
What is the function of this protein?
Non-functional allele of the RF2 fertility restorer of rice varieties with LD-type cytoplasmic male sterility (CMS) (PubMed:21265890).  Non-functional RF2 alleles are found in japonica cultivars Taichung 65 and Nipponbare (AC F1SZ44), and is due to the presence of Thr-78 which replaces Ile-78 in the functional allele (PubMed:21265890).  Functional allele is found in the japonica cultivars Fukuyama and Owarihatamochi (AC F1SZ42), and indica cultivar Kasalath (AC F1SZ41) (PubMed:21265890).
What are the official names of this protein?
Protein FERTILITY RESTORER RF2, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HISZ_RIPO1
Sequence: MIHQPPAGARDLLPLEVVQKAWINDRLQQVFGGWGYQRIVTSTIEWLETLMAGGAIQHSTVIQLQDNSAGQLGLRPELTASIARAAVTRMADTTYPQRLCYRANVFRNPPSGHHGKQLEFYQAGVELLFAGGILADAEILLLVADCLEQLGIPQWQLLIGEAGVTRSLLSPFPDPLKSQVCHCLAQLDYVTLENLDYPSSHLKERAQLLFDLRGNATEVLEKVAKLELDKAGEESINNLKSLMRLINDSRSKPLPLTLDLSVIQTFDYYTGIVFKAVGKTDNQLHILGQGGRYDQLLGVYHPKGQSAPGIGFSFNVEDLYACLLNTSILPQLAPSIDWLIIPQTDEARSTAFQYAQNLRDSGKNLRVAIDLGGRSEAEIREYVQQNRVQQLAWIPEKGEPIIEVIFS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_BORA1
Sequence: MTQRFGKVGVLYGGRSAEREVSLMSGAGVHEALRSAGVDAHLFDTGLQDLTALEAAGFERVFIALHGRFGEDGAIQGALELLNIPYTGSGVTASALAMDKIMTKRVWLQHGLPTPAFEEIDSDTELRRVPDRLGLPLILKPPHEGSTVGITKVAACADMEQAYAAASHFDEVVLAEQFVRGRELTVALLGSGRNARALPVIEIVAPDGNYDYQNKYFTDVTQYFCPADLPVGVAEQIEKIAVQAYRALGCEGWGRADFILDGQNQPWLLEMNTSPGMTSHSLVPMAARAVGMSYAELCVAILADASCKLRAPARANG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_PHOLL
Sequence: MSVLQVLHYPDERLRTIATPVETVDAEIRRIIDDMFETMYAEEGIGLAATQVDIHQRIVVIDVSETRNERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIKALDYNGRPFELQADDLLAICIQHEMDHLIGKLFVDYLSPLKRQRIRQKVEKLDKQKARTK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TIPA_STRLI
Sequence: MSYSVGQVAGFAGVTVRTLHHYDDIGLLVPSERSHAGHRRYSDADLDRLQQILFYRELGFPLDEVAALLDDPAADPRAHLRRQHELLSARIGKLQKMAAAVEQAMEARSMGINLTPEEKFEVFGDFDPDQYEEEVRERWGNTDAYRQSKEKTASYTKEDWQRIQDEADELTRRFVALMDAGEPADSEGAMDAAEDHRQGIARNHYDCGYEMHTCLGEMYVSDERFTRNIDAAKPGLAAYMRDAILANAVRHTP
What is the function of this protein?
Transcriptional activator.  Is activated when bound to the antibiotic thiostrepton.
What are the official names of this protein?
HTH-type transcriptional activator TipA.
Protein: RISB_CORU7
Sequence: MPAEGIPQINLDPGAAEGLRVAVISAQWNAEITDKLHAEAIGAARELGASVEDWRVAGALELPVVVAAACKNFDAVIATGCVIEGETEHFRVVCDAVTYGLTRVSLDTGVPIGNGVLTVANHQQAVDRAGGPEAKENKGADSATAAIHAALVLRQIAAVG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MCH_HALMA
Sequence: MTDWADPDALDLSDGETFDSLLDRADTREKGHFFEFFAEGDELAHDPGLRLTHHGSEQWMGQTLNHDPAYWRADTARERDFEERPVHPDYLLACVMGITVEDLSEKGGYFLGRDDVTFHQPVTAGTPLSVTSTVVDTKTSSSRPQYGIVTWETEGRDRETGETLVSYRRTNMIPRREPAATDGGAVGEQDEDGPMLPDTPISPDGEYFEDFQAALERADTENAAVAYRHERGRTMDDQLVAGLPLATLNTARQHHNRDEMADSPSGDIVAYGDVTRSVALAHARSDEATYRERRFADEQFHDFVTLGDTVYGFTRVLDCDPDAGPERAGAVTFEHVAFNQDQTPVYSGRRTALIQRDT
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the reversible hydration of mesaconyl-CoA (2-methylfumaryl-CoA) to yield beta-methylmalyl-CoA ((2R,3S)-beta-methylmalyl-CoA).
What are the official names of this protein?
Mesaconyl-CoA hydratase, 2-methylfumaryl-CoA hydratase, Beta-methylmalyl-CoA dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: CA1C_CONAL
Sequence: GCCSYPPCFATNSGYC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin blocks mammalian nAChR alpha-3/beta-4 subunits.
What are the official names of this protein?
Alpha-conotoxin AuIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: POTA_STAAS
Sequence: MEPLLSLKSVSKSYDDLNILDDIDIDIESGYFYTLLGPSGCGKTTILKLIAGFEYPDSGEVIYQNKPIGNLPPNKRKVNTVFQDYALFPHLNVYDNIAFGLKLKKLSKTEIDQKVTEALKLVKLSGYEKRNINEMSGGQKQRVAIARAIVNEPEILLLDESLSALDLKLRTEMQYELRELQSRLGITFIFVTHDQEEALALSDFLFVLKDGKIQQFGTPTDIYDEPVNRFVADFIGESNIVEGRMVRDYVVNIYGQDFECVDMGIPENKKVEVVIRPEDISLIKAEEGLFKATVDSMLFRGVHYEICCIDNKGYEWVIQTTKKAEVGSEVGLYFDPEAIHIMVPGETEEEFDKRIESYEEVDNA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNLJ_PSEMY
Sequence: MTDAAQRISELRNELDAHNYRYYVLDEPSVPDAEYDRLFRELQALEAEHPELVTPESPTQRVGGEALSAFGEVRHEVPMLSLGNAFEEDDLRAFDRSVQSGLGLAGGDLFGGGAEVEYSCEPKLDGLAVSLRYENGQLVRGATRGDGSTGEDISANVRTIRNVPLKLQGEGWPQVLEVRGEVFMPKAGFEELNARQAEAGGKTFANPRNAAAGSLRQLDPKITASRPLEFCCYGVGQVSGELPGTQVAMLQQLKAWGIPISRELKLAKGVEACLDYYRDIGQRRMSLAYDIDGVVFKVNNIEDQQQLGFRARTPHWAIAHKFPAQEELTELLDVEFQVGRTGAVTPVARLKPVKVAGVMVANATLHNMDEVARLGVMIGDTVIIRRAGDVIPQVMAVVPERRPADARPVHIPEQCPVCGSAVERTQLIKRSKGKASVSEGSVYRCVGRLSCQAQLKQAIIHFVSRRAMDIEGLGDKTIEQLVDEKLIGSPADLYKLTYEQIIGLEGFAEVSSNKLLAAIENSKRPSLARFIYALGIPDVGEETAKVLARSLASLERVRQALPEVLTYLPDIGLEVAHEIHSFFEDAHNQQVISALLGECGLELQDEGELSAEFSAVATLGGMLDKLNIPTVGPGAAQKLAERFGSLEGVLNGDWLDMRQALPERQAKAVREFFDETANAQRARAIEQQLREFGMHWESEKKVAEGLPLAGQTWVLTGTLEVMSRDVAKEKLESLGAKVAGSVSAKTHCVVAGPGAGSKLAKASELGVKVLDEAQFLEQLKSYGIEA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MNMA_STRPZ
Sequence: MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGKVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.