PharMolix/UniProtQA huggingface dataset:
Protein: DP2L_METMP
Sequence: MLHVSASKGMTEYFKNILDDVSNLYNLAEECRKNGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSEFGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAYVKIKKNSDNSEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDRFKPTEDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRVETNQIRGGALLALVEGVLLKAPKILRHVDKLNIEGWNWLKELKSKKEEVIEELEEENDEYNYEDEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDGSVLKIDTVEKAKQYTDEVQEILFLGDILVNYGDFLENNHTVLPSSWCTEWYEKILKSQNLEYTEEFIKNPGQKEAVNYAKITKTPLHPKYTYFWHDISKENISTLRSWVIGGKYNPSNDSWELNYDPEDEEISNAKRYLELIGCPHIVMEEKVEIFEYYPFLYSLGYDFDEKRDMIDNIDEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAAARKMKPPVNGLFPIGNAGALVRLINKAVDEGKTDEIEIANVKCSCGKVSLYRTCPFCGNSVEPTGPSRIKLPIKDYWYKTLENLKINKPGDVKCIKGMTSKDKIIEPLEKAILRAKNNIYVFKDGTTRFDCTDVPVTHFKPVEIHVPIEKLKSLGYLKDIHGNPLENEDQVLELKVQDVIVPESCMDYFLNVSGFIDDLLEKYYKKDRFYNVNTREDLVGHLIIGMAPHTSAGMVGRIIGYSNANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKMMETIEDRLDKDSQYEGIGYTHETSKIDEGPPICAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGVCRKCGSRLILTVSKGAVEKYMNVSQTMAEKYDASDYIKQRLEIIKSGIDSLFVNDKRKQVKIEDFFK
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: METK_AKKM8
Sequence: MSRNTPHIFTSESVGEGHPDKVADYISDSILDACLAQDKTSRVACETLVKSNMVIIAGELTTKAVIDPEKIARQAIREIGYCNRQDDDVFHADTVFFTNLLTEQSPDIAQGVDAREAEGKGHAEQGAGDQGIMFGFATNETPELLPAPIVFAHKLLIELARRRKRGHVDWLRPDCKSQVAVAYDEDGRPAHIENVVISTQHTEDVDHDTIYSYCVKLIKNVLPAELLDERTEYFINPTGKFVVGGPHGDSGLTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMCRWVAKHIVAAGLADKCELQVAYAIGYPAPVSIRVDTFGTGKVEEISIENALENIFSFKPADMVEQLNLLRPIYRKTTHYGHFTNPELPWEQLDETRLASLKQLLH
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_NEIMF
Sequence: MGGKTFMLMAGGTGGHIFPALAVADSLRARGHHVIWLGSKDSMEERIVPQYGIRLETLAIKGVRGNGIKRKLMLPVTLYQTVREAQRIIRKHRVECVIGFGGFVTFPGGLAAKLLGVPIVIHEQNAVAGLSNRHLSRWAKRVLYAFPKAFSHEGGLVGNPVRADISNLPVPAERFQGREGRLKILVVGGSLGADVLNKTVPQALALLPDDARPQMYHQSGRGKLGSLQADYDALGVKAECVEFITDMVSAYRDADLVICRAGALTIAELTAAGLGALLVPYPHAVDDHQTANARFMVQAEAGLLLPQTQLTAEKLAEILGSLNREKCLKWAENARTLALPHSADDVAEAAIACAA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: H2AX_DANRE
Sequence: MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGQAAASSGKSGKKGSSQSQEY
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
What are the official names of this protein?
Histone H2AX, H2a/x, Histone H2A.X.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: P60_LISIV
Sequence: MNMKKATIAATAGIAVTAFAAPTIASASTVVVEAGDTLWGIAQDKGTTVDALKKANNLTSDKIVPGQKLQITEVASEKTEKSVTATWLNVRSGAGVDNSIVTSLKGGTKVTVESTEANGWYKISYGEGKTGYVNGKYLGTTVTSAPAPEVKEETTTQAQAAPAAETKPEVKQSTPATVLPKAETKTETPAVDTTASTYTVKSGDTIWALSSKYGTSVQNIMSWNNLSSSSIYVGQVLAVKQEAAKTASPKAEVKTEAPTAEKQVSAPVVKENTQTTTAKKEVTPQKQTNTQAPAQAAKPAPAPAPTVNTNASSYTVKSGDTLSKIATTFGTTVSKIKALNGLNSDNLQVGQVLKVKGTVPTANTNSNSNATAPTTNTNNNTSNTSTSTPSKNTNTNSNASQGSSSTASASSLIAEAQKHLGKAYSWGGNGPTTFDCSGFTKYVFAKSGVTLPRTSGAQYASSTKISESQAKPGDLVFFDYGNGIAHVGIYVGNGQMINAQDNGVKYDNIHGSGWGQFLVGFGRV
What is the function of this protein?
This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria.
What are the official names of this protein?
Probable endopeptidase p60, Invasion-associated protein p60.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: CATB_SHEEP
Sequence: MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMPCAHQH
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity).  Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity).  Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity).  Has also been implicated in tumor invasion and metastasis (By similarity).
What are the official names of this protein?
Cathepsin B, Cathepsin B1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: IBP2_ONCTS
Sequence: DLVFYCPKCTAERQTACPKL
What is the function of this protein?
Inhibits IGF-mediated growth and developmental rates (By similarity).  IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 2, IBP-2, IGF-binding protein 2, IGFBP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: SERC_BAUCH
Sequence: MNTVFNFSSGPAKLPIEVLQQAQQELCNWHGLGTSIMEISHRSDEFRQVAYESEQDLRSLLNIPDNYQVLFCHGGARAQFAAVPMNLLGKSKIADYIHGGYWSYSAAKEAHKYCQPRMIEVMTYINGWRGIKPMVEWVLSPDNVAYVHYCPNETIDGLTIDELPDFGNKIVVADFSSAILARPIDVSKYGVIYASAQKNIGPAGLAIVIIRDDLLINRASTKLPSILNYQLLANNKSMFNTPPTFAWYVSGLVFKWLKVQGGLVEIEKNNRAKAILLYNTIDNSEFYYNNILPVNRSYMNVPFYLANSALDDLFIIEARNAGLYALKGHRVAGGMRAALYNAMPLEGVKTLVQFMHNFACRYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGCP_PSEAB
Sequence: MSRDDVQRWKDKYLENIEQQERLQRRWDARIDLLRRGLVRSSLAAEGSDKAVDQCMKELREILRRDDMDAGLSGLIPRLEKAVLDSEQRRQQRTQQNIDALGELAQQLLALDLPRELRKPLKQFARDIEERARQSREIPILLSELSRLQRQALAERKGGDAEDGRPSLLQRLFGGKESETAAEPSASVPSVVAASNTPIQPAAAAPSLPVAEHDEAPGGPPQPLPASRVAAIESAPAGWVGVAERGEPNQILLDEPREIWLDSLPLPAGLSFSETLEDAGAESPPAVPADVESAPEAPATPVDNLDGQAVDEAYELPPPIPEPGYSAVAPHIEASLLRLLDGLSLPSSHQPQAEALRERIDGSLNWYELVPVLDDLAVLVLSLADSGQRDFEEYLRQLNERLESFLGHLGDAHAGYTDVLDNARGFDQSLREQVSGLQASVQQATDLNSLKLAVDSRLNGLLASMDEHQREQAEHEQEVSGRLQALMERVNSMEQDAKAFHSHLEDQRQKALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITCSAGITAFEGNEAGEVVFERADQALYRAKRAGRDRLEVA
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules.  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (By similarity).  Localizes at the cell poles through interaction with FimV where it increases the local pools of c-di-GMP (PubMed:32080219).
What are the official names of this protein?
Diguanylate cyclase DgcP.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Localizes at the cell poles in a FimV-dependent manner.
Protein: LPXA_YERPN
Sequence: MIDKTAFIHPSSIVEEGAIIGAGVYIGPFCIVGSQVEIGAGTELKSHVVVNGITKIGCDNQIYQFASIGEANQDLKYAGEPTRVEVGDRNRIRESVTIHRGTTQGGGVTKVGCDNLLMVNTHVAHDCVIGNRCILANNAALGGHVEIDDYAIIGGMTAIHQFCVIGAHVMVGGCSGITQDVPPFVIAQGNHATPFGINIEGLKRRGFDKESLHAIRSAYKLLYRSGRTLDEVKPEIAELAEQYPVVKAFNDFFARSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCN4_RABIT
Sequence: MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPRRRSIRLRPLPSPSPSPSAAAAAAGGAESRGAALGGAADGEGPARGAAKSSTNGDCRRFRGSLASLGSRGGGGGGGSTGGGSHGHLHDSAEERRLIAEGDASPGEDRTPPGLAAEPERPGAPAPPAASPPQVPSSCGEQRPADAAVKVEGGAAAGDQILPEAEARLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVEDNTDIILDPRRIKMKYLKSWFVVDFVSSIPVDYIFLIVETRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSLNNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPMGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLSSGVSNYQENAIVQRIVQHDREMAHCARRAQATTPVAPAIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPTTLGSLGAGQTPRHLRRLQSLAPSAPSPASPASSPSQPDTPSSASLHVQPLPGCSTPAGLGSLLPTAGSPPAPTPPTTAGAAGFSHFHRALGGSLSSSDSPLLTPMQSAARSPQQPPPPPGAPAGLGLLEHFLPPPARSPTSSPGQLGQPPGELSPGLGSGPPGTPETPPRQPERLPFAAGASAGASPVAFSPRGGPSPPGHSPGTPRTFPSAPPRASGSHGSLLLPPASSPPPPPPPPAPQRRATPPLAPGRLSQDLKLISASQPALPQDGAQTLRRASPHSSSGESVAALPPFPRAPGRPPGAGPGQHVTLTLPRKASSGSLPPPLSLFGPRAAPAGGPRLTAAPQREPGAKSEPVRSKLPSNL
What is the function of this protein?
Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions.  May contribute to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat.  May contribute to the native pacemaker currents in neurons (Ih).  May mediate responses to sour stimuli.
What are the official names of this protein?
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, Hyperpolarization-activated cation channel 4, HAC-4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel HCN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCP_SHIDS
Sequence: MIMFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTKGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFLYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATNVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP9_MALDO
Sequence: MLEGAKSIGAGAATIASAGAAIGIGNVFSSLIHSVARNPSLAKQSFGYAILGFALTEAIASFAPMMAFLISSVFRSVSRVTI
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: METK_BACHK
Sequence: MTKKRHLFTSESVTEGHPDKICDQISDSILDAILSKDANARVACETTVTTGLVLVAGEITTSTYVDIPKIVRETIQGIGYTRAKYGFDAETCAVLTSIDEQSADIAMGVDQALEAREGQMTDAEIEAIGAGDQGLMFGFACNETQELMPLPISLAHKLARRLTEVRKNDTLSYLRPDGKTQVTVEYDENGKPVRVDTIVISTQHHPDVTWEEIDRDLKEHVIKAVVPAELIDGETKFFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNIVAAGLAEKAEVQLAYAIGVAQPVSISVDTFGTGKVSEDVLVELVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRTDVDLTWERTDKAAALKEQAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGR_STRM5
Sequence: MSDGNDTAVHDVHAADAADERFLVRNPRQLRQLLRSLIDQRSLINAHIDGRDRSFPTALLELDEDEDYLLLDGSPQEASNRAAEQADHLLCFAQLERVLVRFRLQELQRVDNDGHVAFRAPLPDELVHLQRRELYRLETPVTDSPQLQLPAAEDRSEALSMRVVDISGGGLAVVVPTDCAVFSLQKRYPAVLSLPDGPDLEIELVVCNLLPQRQPNGIEIKRVGMRFDILPRGGDSAIQRYIFRIDRQRKARRNGEL
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: GPR_ECOLI
Sequence: MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQHIADGELNLWQASSDK
What is the function of this protein?
Catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP).  The physiological role of gpr is the detoxification of L-GAP, which may be formed by non-enzymatic racemization of GAP.  Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo.
What are the official names of this protein?
L-glyceraldehyde 3-phosphate reductase, GAP reductase.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
Protein: MTGA_JANSC
Sequence: MAKRARKSKKNVSRARLLAQAMRRWLLRGMFGLGALMLVWIVAYAVVPVPTTIYMQQERARLGGIERDWVPMDQIAPVLARSVVAAEDANFCLHWGFDMTAIRDAIADGAARGGSTISQQTVKNAFLWHGRSWVRKALEAAITPVMELVWPKRRVLEVYLNVAEFAPGVFGAEAGAQHHFGVSAADLTARQASLMAAVLPNPQRRDAGSPSDLVNRRARSIADGAALIRADGRADCFAN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HUNB_DROLI
Sequence: WYSSMFAANIKQEPISHHHHHHHAHHSHHQHPHDSNSNSNASSPHQSPLPSPNPPSNTNLQLEQYLKQQQQQQQQQQQQQQQQPMDTLCAAAMTPSPSNNDQNSPLMLPGLPNPMQSIMLANLRPSPTTTTTTTTPAAAPTTTAATIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEPEKEHDLMSNSSEDMKYMA
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_THEP1
Sequence: MIDIKLIRQNPDLVKEALRKRGEDPATIDEILKIDADWRTTITKTNELRSRRNEISKNVARLKKEGKNTEAEALIEEGKRLGEEIKALEEKEKELQKQLNDLLLMVPNIPHESVPVGEDESQNVEVRRWGEPREFDFTPLAHWDLGPAWGLMDFDRATKLSGSRFTVMYGKLARLERALINFMLDVHTKEHGYTEVWVPHLVKRETITITGQLPKFEEELYLAERDDLFLIPTAEVPLAALHSGEILEEKELPKKYVAYTPCYRREAGSYGKDVRGMIRQHQFDKVELVWVTTPERSFEDLEQLVKDAETILQKLELPYRVVSLCTGDLGFTSAKTYDIEVWLPSYNAYKEISSCSNVTDFQARRGNMRYRRRSDGKLEYVHTLNGSGIAVGRALVAILENYQQPDGSVRVPEVLVPYTGFEVIP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTA_ECOBW
Sequence: MQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: FOLT_CLONN
Sequence: MKKVNVMIYMAFMITLEIVFTRFLSIQTPIIRIGFGFIPVAMSGMMFGPLLAGIVGATSDVLGMMIFPKGAYFPGFTLSAFVGAVIYGVFFYNKKVSVKRVLLAVGIITVLVNLTMNTIWLQILTGKAVKVLFVTRLVKEAIMFPIHAIVIYGAWKMVDRLEIMNKVAKFNK
What is the function of this protein?
Folate-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).
What are the official names of this protein?
Folate transporter FolT, Folate ECF transporter S component FolT.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR7_ECOLI
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What is the function of this protein?
Converts 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) to 4-(N-succinylcarboxamide)-5-aminoimidazole ribonucleotide (SAICAR).
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: COBD_METMP
Sequence: MINPIYLILADFFDRYIGEPPEKVHPVVFIGKLISFFENVFKSTNSVNKNRDLLFGFLNVVLVLAIVFFMAFEIEQAINSISNSYIRISLYSIILSFSIGHKSLIEFSKSPIKFIVNNDLESAKKSVQCIVSRNTNELDKKHVLSASIESASENITDSIIAPLIYAAIFGLPGAFLYRAVNTFDAMIGYKSEKYLYYGKTAAYLDDILNFIPSRIAGMLLIISAPFYGGNVKSALLGYFNEGSKTPSPNSGYTMATLANSLSMELEKIGYYKLGKGEITVEKALNSLKAVDYSVLLFLIIYMILFM
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Probable cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNTP_ESCF3
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGIRGGDDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGPILGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y593_MYCLE
Sequence: MTRTSETTKSPAPELLTQQQAIDSLGKYGYGWADSDVAGASARRGLSEDVVRDISAKKDEPEWMLQARLKALRVFERKPMPRWGSNLDGIDFDNIKYFVRSTEKQAASWDELPEDIRNTYDRLGIPDAEKQRLVAGVAAQYESEVVYHQIRADLKDQGVVFLDTETGLREYPDIFKQYLGTVIPAGDNKFSALNTAVWSGGCLTADARINVKGKGLVSIADVQPGDEVFGVNIGCELERGKVLAKVASGTKPVYEMHVAGRALEATGNHQFLVARRVEEGKRTRWTAVWAPLEEIESGEPIAVARVLPDDSGTIFFSESELDIKNRTRQCLYFPCQNSVDLLWLLGLWLGDGHTAAPHKHMRQVAFSVPAGDPVHHTAIRVVSEQFGANVTVVNCGFIVSSKAFETWLAELGFSGDEKTKRLPAWIYSLPHEHQLALIGGLVDADGWTESSGATMSIAFASRELLEDVRQLAIGCGLYPDGALVERTRSATCRDGRIVTSTSWRLRIQGSLDRVGTRTPGKRGKPVSNKGRRQRYVAAAGLNFSSLSTDTVGFARLKSKTLVGEKPTYDIQVVGLENFVANGIVAHNSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADTGSYVHYVEGCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARVETGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEGQHQDTGAKMLHLASNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTISRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLAEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG
What are the official names of this protein?
UPF0051 protein ML0593.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.