PharMolix/UniProtQA huggingface dataset:
Protein: MDL1_YEAST
Sequence: MIVRMIRLCKGPKLLRSQFASASALYSTKSLFKPPMYQKAEINLIIPHRKHFLLRSIRLQSDIAQGKKSTKPTLKLSNANSKSSGFKDIKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAKEVRNVFHIGLKEAVTSGLFFGSTGLVGNTAMLSLLLVGTSMIQSGSMTVGELSSFMMYAVYTGSSLFGLSSFYSELMKGAGAAARVFELNDRKPLIRPTIGKDPVSLAQKPIVFKNVSFTYPTRPKHQIFKDLNITIKPGEHVCAVGPSGSGKSTIASLLLRYYDVNSGSIEFGDEDIRNFNLRKYRRLIGYVQQEPLLFNGTILDNILYCIPPEIAEQDDRIRRAIGKANCTKFLANFPDGLQTMVGARGAQLSGGQKQRIALARAFLLDPAVLILDEATSALDSQSEEIVAKNLQRRVERGFTTISIAHRLSTIKHSTRVIVLGKHGSVVETGSFRDLIAIPNSELNALLAEQQDEEGKGGVIDLDNSVAREV
What is the function of this protein?
Mediates export of peptides with molecular masses of 2100 to 600 daltons generated upon proteolysis of mitochondrial inner membrane proteins.
What are the official names of this protein?
ATP-dependent permease MDL1, mitochondrial, ABC transporter MDL1, Multidrug resistance-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UHRF1_HUMAN
Sequence: MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFYRGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQSESDKSSTHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVTRKAPSRDEPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDPPLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSSSQRDWGKGMACVGRTKECTIVPSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRAGSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVNQPLQTVLNQLFPGYGNGR
What is the function of this protein?
Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification.  Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication.  In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.  Enriched in pericentric heterochromatin where it recruits different chromatin modifiers required for this chromatin replication.  Also localizes to euchromatic regions where it negatively regulates transcription possibly by impacting DNA methylation and histone modifications.  Has E3 ubiquitin-protein ligase activity by mediating the ubiquitination of target proteins such as histone H3 and PML.  It is still unclear how E3 ubiquitin-protein ligase activity is related to its role in chromatin in vivo.  Plays a role in DNA repair by cooperating with UHRF1 to ensure recruitment of FANCD2 to interstrand cross-links (ICLs) leading to FANCD2 activation.
What are the official names of this protein?
E3 ubiquitin-protein ligase UHRF1, Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, RING-type E3 ubiquitin transferase UHRF1, Transcription factor ICBP90, Ubiquitin-like PHD and RING finger domain-containing protein 1, hUHRF1, Ubiquitin-like-containing PHD and RING finger domains protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to replication foci. Enriched in pericentric heterochromatin. Also localizes to euchromatic regions.
Protein: CAPSD_CMVPE
Sequence: MDKSESTGAGRNRRRRPRRGSRSAPSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRESYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDTLETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DNAK_PSEPK
Sequence: MGKIIGIDLGTTNSCVSILENGNVKVIENAEGARTTPSIVAYANDGEILVGQSAKRQAVTNPHNTLFAVKRLIGRRFEEDVVQKDIKLVPYKIVKANNGDAWVEAAGKEMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDMRLIDYLVDEFKKESGMDLKNDPLALQRLKEAAEKAKIELSSAQSTDVNLPYITADATGPKHLNVKISRAKLESLVEDLVKRTIEPCRIALKDAGIDASKIDDVILVGGQTRMPLVQKEVADFFGKEARKDVNPDEAVAMGAAIQGAVLAGDVKDVLLLDVSPLTLGIETMGGVMTALIEKNTTIPTKKSQVFSTADDNQSAVTIHVLQGERKQAAQNKSLGKFDLADIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKTQSIVIKANSGLSDEEIERMVRDAEANAEEDRKFEELAAARNQGDALVHSTRKMVADAGDKVTAEEKTAIEAAVVALEAAVKGDDKAAIDAKVEELSKVSAPVAQKMYAEQSAEQPQGGAQQAEPEAKHDDVVDAEFEEVKDNNKQ
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: QUEA_RICTY
Sequence: MKLSDFDFNVPNALIAQYPSSERDNSDLLIAGTKHIKTKFYNIIDYLKEGDLLVFNNSKVIKAKLHLGKNITINLNKKLSDNCWGAFAKPARKLNIGDEFYFDTHKIIITEKLAMGEIKVKFILNNISMIKFLDKYGEMPLPFYIKRTSSVCCSNMALFCDHDNTLKITSISHNSNTVNFRSTDSMIDSTNDNDRYQTIYSQIEGSVAAPTAGLHFTKDILDKLKTKGINTAFVTLHVGAGTFLPVKTENIHKHKMHTEYCSITAETAEIINKTKQKGRDIIAVGTTTLRTLESSCNNGIVKAGNFETDIFITPGFNFQIVDMLLTNFHFPKSTLFILICAFAGFKEMHALYKYAIKEKMRFFSYGDATLLYRKV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STN1_XENTR
Sequence: MQPASLEETPSLLWGLDPIFLAFAKLYIKDILELKESQQVPGIFFYRGHPIKQVDVLGTVVFVREKENFYSYGVDDSTGVISCTCWKSTAPTEVSSPGTSARHVSSSSKDLDVMMRELYKEESKKAKLDIGDTIRVRGSIKVFRDQREIVASVFYKVEDPKLDIQMARMFDLPYMYRNVYDKPFAIPEHLKDSSAGQTDHHIVTQSHLIMLLSEKVKVFLMENKIHNFYQRELESVDSLIAIASRPVSDFKTIESMESSNSKQIRSIFKEAIQLLLKEGYIFQKDQNREVYQVTDQDKDLHKLTLNIIKEDCRRQKHAEKGCHFLHILTCVRLSVGSSVSEAVLRRVIDTLEGNSDIVSTMENYYTAF
What is the function of this protein?
Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex.  The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves.  Initially the CST complex has been proposed to protect telomeres from DNA degradation.  However, the CST complex has been shown to be involved in several aspects of telomere replication.
What are the official names of this protein?
CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog.
What is the protein family that this protein belongs to?
Belongs to the CTC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RL27_ECO7I
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: COUO_STRRH
Sequence: MKIEPITGSEAEAFHRMGSRAFERYNEFVDLLVGAGIADGQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQGKELEFRHGDAQSPAGMEDLLGKADLVVSRHAFHRLTRLPAGFDTMLRLVKPGGAILNVSFLHLSDFDEPGFRTWVRFLKERPWDAEMQVAWALAHYYAPRLQDYRDALAQAADETPVSEQRIWVDDQGYGVATVKCFARRAAA
What is the function of this protein?
Mediates C-methylation at the 8-position of the aminocoumarin moieties in coumermycin A1 in the biosynthetic pathway of coumermycin antibiotic.  Active on both mono- and bis-amides for mono- and di-C-methylation adjacent to the phenolic hydroxyl before it is glycosylated by CouM.
What are the official names of this protein?
C-methyltransferase CouO, Coumermycin biosynthesis protein O.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: Y2658_SYNP2
Sequence: MFFKIPQVLTPEALEKITTTLTEAEFVDGKLTAGWYAKLVKENQQLAKATPTAQALEEQVRQALQSNALFQTAIRPKTVHTLLFSRYGPGMAYGRHTDNALMNGMRSDVSFTLFLNEPSDYEGGELVIEGADSEQSYKLPAGTAIAYPSTSLHRVNVVTKGTRLVAVGWVQSWIRDAQKREIVFDLDVSRRSLFAQSGKTTEFDLLSKSVANLLRLWSE
What are the official names of this protein?
PKHD-type hydroxylase SYNPCC7002_A2658.
Protein: YIDC_CHLPM
Sequence: MDRNSVTGLALIALIMIVWLQFMSPDKKPVIRESAKKAASVEQVNVPLKPAPVSASDAFGAFASAANGKARKMVVENDLFRATISSKGATLTSLVLKKHLDGALQPVQLVSNRADGALSLLFLTREGRKIDTRDLYFTGGSVDTLHTVTGKESYSVRYRLNVSKNRNILITYSFTGDSYRVGYDVQLNGFSSALAGNEYQLQWDGGLGYTEKNREDEAHNALAGAYLGGSLVKLDAAKDNQAYREEQSGEAKWVAVRNKYFVAALIPAGPTGGFYLDGSKKAGNEFENYLASLKMEVPVSGASLDNSFSLYMGPLDYDIVRAQKAELEKIMDFGWDWLTRPFAEYIILPVFSWMNKFIHNYGLIIIIFAFLIKLVTYPLSLASTKSMKKMAALQPMLKELQDKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIELRQHGFLWAHDLSVPDSILNLGFTIPMYGDHIALMPILMAGTVFVQQKITPTAQTNDQMKIMLYMFPAMMLLFFNNMPSGLGLYYLMFNVFSVAQQFYINSTTTEADMPNVSIAAPARQKKKKSGGGK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2615_ALKCK
Sequence: MTLLIRDVPQTERPRERFIREGAKALSNQEIVAILLRTGTKQSSALHVASTLLSQFPTLAMFSEAPLEEIQKVPGIGMAKAIELSAAIELGRRIQRETKLVRPVISSPEDAAELVSEDMRGLQQEHFVALYLNTKNHVIKQKTLFIGSLNASIVHPREVFKEALQSSSASVICLHNHPSGDPSPSPEDISVTKRLRQAGAILGIELLDHIIVGDGCFISLKERGFFATIS
What are the official names of this protein?
UPF0758 protein ABC2615.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RS16_DESHY
Sequence: MATKIRLRRMGAKKNPFYRLIVADSNAPRDGRFIEEIGFYDPTKQPEVLNIDEEKAMKWLATGAQPSDTAKSLLRKAGVLAKYHESKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SHO1_FUSV7
Sequence: MYGGRKGIQMSNILGDPFALATLSIAMLAWCITFVACIIGRIQQTNDSPFPTFAWWGCIYSLCLIVGVFVVIGSDSVHTYHVAVTGYLAAGIVLVSSGVNLLLYSDSGAREAASAGFILLAMVIVIWTFYFGSNPSSTPRAFLDSFALAKESTTIHRSTMNGYGGGGRPETSNSVQPPQMYTSAQLNGFENPSPVGGVSQVGGRGSAVPQSFTNSVMQPKATNSPGADAEVVPPTEYPYRAKAIYSYEANPDDANEISFSKHEILEVSDVSGRWWQARKENGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEPA_BUCAI
Sequence: MLKCIKHEYGIKNMKSIRNFSIIAHIDHGKSTLSDRLIQLCGGLSEREMSNQVLDSMDLEKERGITIKAQSVMIDYKNKSGNIFNLNFIDTPGHVDFSYEVSRSLAACEGALLVVDSTQGVEAQTLANCYTAIDMNVEIVPVLNKIDLPNSNADKVAKEIEDIIGIPALDAIRCSAKTGEGIEDLIERIINDIPYPKGSINSPLQALIIDSWFDNYLGVVSLIRIKNGILFERDKIQVMSTGKNYYVDQIGVFTPKKLNKNQLRCGEVGWIICGIKNIIAAPVGDTLTTAKNPAKNMIIGFKKIKPQIYAGLFPLTSDQYEMFRDALGKLSLNDASLFYEPENSVALGFGFRCGFLGVLHMEIIQARLEREYSIDLITTIPTVIYEIELINGKIIYLDTPSNFPNMNDIKIIKEPIVECSILSPPQFLGSIIKLCIKKRGVQINMVYHSHQVLLKYNIPMNEVILNFFDELKSVSSGYASLEYDFKYFQSVKMVRIDILINSEKVDALTILSYHKNAQSRSREIVDKMKKLIPRHQFDISIQAVINNSVIARSTIKQLRKNVLSKCYGGDVSRKKKLLQKQKDGKKRMKKIGNVNVPKTVFLSILNSRES
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MCM9_BOVIN
Sequence: MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGNDMGRFFLASERVRKEEVSCSNKSSKVHACTLAKLANFSFTSPSESKSESPPPPQSKNPSEGGPSCVATATALGRKRKTFQLDTSTEKLSLSKTSLFTLPELDDEPLDFDWDEEMRKKP
What is the function of this protein?
Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR).  Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity.  Probably by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs.  Acts as a helicase in DNA mismatch repair (MMR) following DNA replication errors to unwind the mismatch containing DNA strand.  In addition, recruits MLH1, a component of the MMR complex, to chromatin.  The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression.  Probably by regulating HR, plays a key role during gametogenesis.
What are the official names of this protein?
DNA helicase MCM9, Minichromosome maintenance 9.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes to nuclear foci with RPA1 following DNA damage. Localizes to double-stranded DNA breaks. Recruited to chromatin by MSH2.
Protein: TRPB_CHLTE
Sequence: MKQKVIYSAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKNDPEFHQTLDNLLRHYVGRPTPLYHASRLSEKQGGAQIWLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGAGQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLLGTEVRPVTAGSRTLKDATSEAIRDWMNNPEETFYIVGSVIGMHPYPMMVRDFQSVIGRETRQQVLDQAGRLPDVIVACVGGGSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGKHAASLTKGEIGVLHGSMMKLLQDEYGQVQEAHSISAGLDYPGVGPEHCYLQKLGLVCYTSTTDKEALAALDALAKTEGIICALESAHAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMQELKL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ISPG_ANAMM
Sequence: MVGCRAASDAAEFESVVGSSRVARVSCAVRVGRVIIGGGSPVVVQSMALGGSGSLSSDLEEILCLAKEGSELIRVAINSEESIKSIPRIVEHLVSHGFDEKMVVGCGQYEVADLLNKYPDDAAFLGKIRINPGNVGFGDKRDRNFESVIEYAIKHDIPVRIGVNWGSLDKALIGKLMDDNASLASPYPDNVVMRKALVTSALQSAELAERIGLPRNKIVLSCKTSKVRDLVAVYSALSESADYALHLGLTEAGTGLKGIVSSTAGIAHLLLMGIGDTIRVSLTSTSREDRAQEVRVCKEILQSLGLRFFSAQTTSCPGCGRTNFPYFQKLVSGVNHYIDRRMQVWKVSNPGVVNMTVAVMGCVVNGPGESKHANLGISLPGNGEREVAAVYEDGRKLCTLHGENVLGEFLEIVESYVHRKYG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RDH11_HUMAN
Sequence: MVELMFPLLLLLLPFLLYMAAPQIRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFFIKTPQQGAQTSLHCALTEGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12226107, PubMed:12036956, PubMed:29410696).  Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal (PubMed:15865448).  Has no dehydrogenase activity towards steroid (PubMed:12226107, PubMed:12036956).
What are the official names of this protein?
Retinol dehydrogenase 11, Androgen-regulated short-chain dehydrogenase/reductase 1, HCV core-binding protein HCBP12, Prostate short-chain dehydrogenase/reductase 1, Retinal reductase 1, RalR1, Short chain dehydrogenase/reductase family 7C member 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RM11_ACACA
Sequence: MRINLNFHYDKLHLKEIIILIPKYHTNMVSFLTPILGLYGINVKEFINDFEIKTRFINFDVIVPTLVKISKIKTFEIILKTPYVISILSNLNNFSVTKPNIDLLSVYKISLLKSVFHSNFLDVFHRRIYLSLRKYLSLVIKVNFHLSVSSALAKKSLSNLNNLLLLKFNIQNNILFAKLLNNRYGLFVSFNNSSASNLNYLKTVLAIQNISIFKAKSNLLSSLTGNKYFFGNIYFIGATSLKYFIGFLKEVSLKSFGSNFFPIFFKIRSNLVSQPFVKLFLSVFNSQVKLINFYALRVIYTIFIKIFKNLNFLNKKLTFLLNRNNSNSNANISSNIKES
What are the official names of this protein?
60S ribosomal protein L11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BTAF1_SCHPO
Sequence: MTTRLDRLVVLLDSGSTSVVRETAAKQIGDIQKVHPDELYNLLGRVVPYLKSKNWDTRVAAAKAIGGIVENVPVWNPNRTSPVKKEETEDLPSFNGDTEEKPFIKTEEGAPASSQSQVVVSSNLTSNSEVSKLEEERLSTRSHSQEIKPIVDFGPDEETAKELNTELKGKFENSLLSFESFDIANVLKAGKKLLGSASRDYDVNPANYSTHYLQQLSNLKSRLDLAGEYLDDSIMNDLGDNVGSNSKGSPTTSIPEHKTSINNNKPEDTPTPSENVHLSARQRNALKRKARQMKNSQKVRVIDVAPTLVHQQNSTSSADKKTGADYNFTAQSRSDRLVVEHKAPIVPSAAVAVTSDSVWPFETLVELLLIDMFDPSWEIRHGACMGLREIIRYAGFGYGRVVGKSEAENEQLNKKYFDDLLCRIACVFALDRFGDYLADQVVAPIRESVSQVLGVALIYVPNDSVFSMYKVLHSLVFQNELGLTNTVWEAAHGGMLGIKYLVAVKYPLFFSHSDYLDSLINTVIHGLANHDDDVRAVSALTLLPIADKLVQEKLSSCKNLLKVLWDCLDDVKDDLSSSTSCVMDLLSSLCSFTEVMNLMQETANSDPEFSFETLVPRLFHLMRYTLTGVRRSVVYALTKFISVQTSCSWITGLTLRLCFQNVLLEQQEDISKSSCELAQRVMDILYRDGPESFSKLLYSHIEPMLKVSITPIGSFRRPYPLDTTLIVKPSGQPYAPSTSRERNNNISELSNSRTKHRAKDDPKGSFCFSVDEPMLNGDVEFVGEERMLKARLRASSLLGRIIGRWKRDEILLFFKPFLQACLTSSFSTPVVLGSRLIESFFEVEDNDLTIQKDELYHLLCDQFATVPRENYANLVSQLHVVRAQCNALLNTFLDVGRLSRSKIPSLAVVVKGDPEAGPIAFGIADAEKLVGPTYENLCKLLSPSQKAQSSKALNEIKYLIIDEISIYKIAKERQDIQCSASIASAMVTYDKLPKKLNSIIKGIMESIKKEQFSCLQMHSASAMMKLISACYKESRQVISEKIVRNLCAYVCMDTTETPIFHDSGKNGILSLHSIGTSDDNDEQVSGKLVDDSDDVSNDRKSSLSSVSDKDAAVLQRMGAQLTLQQMAQNFGSSLFSRVPVLSQCLFVPLQQYAESGFPSEVDQASCTVGQDLLDAMSILRFLVAYLDSGLQSEIVSTLPHLLATLQSNYSAVRNMASKCFAAITESNAAGSKALHLLVEDVVPLLGDASSTIHRQGAIECIYHVVQRLGVRILPYILYLIIPLLGRMSDADQDVRVLATTSFATLVKLVPLEAGLPDPPDLPQYLLDSREKERKFLEQMLNPSKVEAFSIPVPISADLRKYQQEGVNWLAFLNKYELHGILCDDMGLGKTLQTICIVASDHYNRQKLFEESGSPKFAHVPSLIVCPSTLAGHWQQELSTYAPFLKVSAYVGPPAERAKIRSKMKKSDVVVTSYDICRNDVDELVKIDWNYCVLDEGHVIKNARAKLTKAVKSLRSYHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKTFQERFVRPIAASRDAKSSSKERERGTLALEAIHKQVLPFMLRRLKEDVLADLPPKIIQDYYCDMSDLQRKLLNDFVSQLNINEELEDDETEKTQGTRKKKSQKAHIFQALQYMRKLCNHPALILTEKHPKRNAIVKQLAKENSGLHDLKHAPKLTALGQLLRDCGLGNSSVNSNGIDSALTNAVSEHRVLIFCQLKDMLDMVEKDLLQATMPDVTYMRLDGSVEPTKRQEAVTKFNNDPSIDVLLLTTHVGGLGLNLTGADTVIFVEHDWNPMRDLQAMDRAHRIGQKKVVNVYRLITRGCLEEKIMGLQRFKMNVASTVVNQQNAGLSSIGTDQILDLFNTTADEQQTVQNIDKEESEDAAGRGLSGTSKKALEGLPEMWDESQYDEFNLDGFISTLPKDAS
What is the function of this protein?
Regulates transcription in association with TATA binding protein (TBP).  Removes TBP from the TATA box via its ATPase activity (By similarity).
What are the official names of this protein?
TATA-binding protein-associated factor mot1, Modifier of transcription 1, TBP-associated factor mot1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
Protein: CSRA_THEAB
Sequence: MLVLSRKIGQSIIIGNDIEIKILKIDGGEIKIGIEAPKDVKVLRKELYEELLKENKEAVKFDIKNLPGFFKKK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_MYCTU
Sequence: MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: NFU1_DROPE
Sequence: MSKLLSYTARIILRNSRITVRQLVRGFAGFVSGQRNAPQPAYGRPVPGLLRQKMVSSIGKRSMFIQTQDTPNPDSLKFLPGVEVLGKGNTYDFPSGTAAHCSPLAKLLFRVEGVRAVFFGSDFITISKEESAEWSLIKPEVFAVIMDFFASGLPILHEARPNADTEILDDDDETVMMIKELLDTRIRPTVQEDGGDIVFISYENGVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDDADRMADKEFERFEKNLKQKEPAGAPVGIGGGPN
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.
What are the official names of this protein?
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion.