PharMolix/UniProtQA huggingface dataset:
Protein: TPIS_BRUSU
Sequence: MTPGIRPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGLGGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGLVAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAENTIIAYEPVWAIGTGLTPTVQDVRAAHAFMREQLIERFGAKGAHLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAADFLAICETYRNL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_LIGS1
Sequence: MAQVQYQGTGRRKNSVARVRLVPGTGKITMNGKPAEEYIPFANIREDMVQPFGVTETKGQYDVFVNVNGGGFSGQAGATRHGIARALLEVDPDFRGVLKSTGLLTRDARMKERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TOM20_BOVIN
Sequence: MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGEYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial 20 kDa outer membrane protein, Outer mitochondrial membrane receptor Tom20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: NUOCD_AERHH
Sequence: MKLTREFPSNYAMAQWQPSDHKDAQVIGELFAHFGAERFTIQNTRTGVPVVWLSRELLLDVMGFLRKLPSPFVMLFDLSATDERMRSHRHDLPDSDFTVFYHLISIDRNADLMLKVPLKEGDLTLPTVSRHFPNANWYEREVWDLMGINFDGHPHLTRIMMPKSWQGHPLRKDYPARATEFDPFMLDAVKQDQEQDNLLFKPEEWGMARGNENEDYMFLNLGPNHPSAHGAFRLVLQLDGEEIRDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRVEYLGGVMNNLPYVLAVEKLAGIKVPQRVDMIRVMLAELFRIQSHLLFIGTYIQDVGAMTPVFFTFTDRQRIYTIIEAITGARMHPAWFRIGGVAHDLPVGWQRLVQDNLLSWLPKRLMDYEKAAMRNSILRGRTIGVAAYNTEQALAWGTTGGGLRATGLNFDVRKWRPYSGYDQFEFEVPVGANGDAYDRALVRIEEVRQSMRIIEQCMKNMPEGPFKADHPLTTPPPKERTLQDIETLITHFLQVSWGPVMPAAESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSFAHLQQIPSVIRGQMVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HISZ_CUPNH
Sequence: MSNHWLLPENIADVLPSEARKIEELRRRMLDLFRTYGYELVMPPMLEYLESLLTGTGHDLDLRTLKLVDQLSGRTMGLRADITPQVARIDAHLLNRPGVTRLCYAGNVLHARPAGFHATREPIQIGAEIYGHAGLEADIEIQDLMLAALQAAGLSDVRIDMCHAGILEALLAGLPSIRKIEDALFAALETKDVPALRELTVGMPQTERDALLALPTLYGGVDVIDRARATLPASPAIGRALDELAALAVQVRGASVNIDLSDLRGYHYHSGVMFAAYVAGLPNYVARGGRYDKVGEAFGRARPATGFSLDLREVAALSPVEVRAQAIFAPWDADPALRAAISALRAAGEIVIQSLPGHTHELDEFNCDRQLVRQDAGWAVVPR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_PECCP
Sequence: MIIDLNADLGEGGENDEALLKLVTSANIACGFHAGDAQTMRQSVRWGIGYGVALGAHPSFPDRENFGRKAMNVPAEIVFAQMVYQLGALSAIVAAEGGTLSHVKPHGMLYNQAACEPALADAIAKAVKVVNPALRLVGLAGSELIRAGQRLGLETRQEVFADRCYLPDGTLVPRTQAGALINSDELALAQTLEMIQRQRVRAIDGSWVTVQADTVCIHGDGQHALLFARKLRSCFSEHQITVAAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: BDSA_ANEVI
Sequence: MNKALFLCLVVLCAAVVFAAEDLQKAKHAPFKRGAQVCFCPGKVDRGDLWILRGDCPGGYGYTSNCYTWPNICCYPQSFSGR
What is the function of this protein?
Blocks Kv3 voltage-gated potassium channels.  Reduces blood pressure.
What are the official names of this protein?
Kappa-actitoxin-Avd4j, Kappa-AITX-Avd4j, Antihypertensive protein BDS-10, Blood depressing substance 10, BDS-10.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: MURC_HAHCH
Sequence: MKNTVWGPPEMRRIRRIHFVGIGGSGMCGIAEVLLNQGYEISGSDLKESATTRRLSDMGASITFGHTAQNIAGANVVVTSSAVAKDNPEVTAANEQRIPVIARAEMLAELMRYRHGVAIAGTHGKTTTTSLMASVLGEAGLDPTFVIGGRLNSAGTNAKLGASRYLVAEADESDASFLHLTPMVSVVTNIDADHMHTYGGDFEKLKQTFVDFLHNLPFYGVAVMCYDDPVVREIIPRVGRSVITYGFNEKADVRAVDIAQQGMQTSFTAKRPGGHPDLRISLNMPGKHNVLNALAVIAVATDEGIADEAIVSALNKFQGVGRRFQVYGNYPVDEGSVMLVDDYGHHPREVDATIKAIRDGWPEKRLVAVFQPHRYTRTRDLYEDFVQVLSKVDVLVLMDVYPAGEKEIPGADGRSLCRSIRQRGQLDPIFIERGQDVKAVLSGVLQDGDLLLTQGAGDIGAVAGVLAEGGLQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_HELPY
Sequence: MKNTSSSTTLTMNDTIAAIATPLGKGAISIIKISGHNALNILKQLTQKQDFTPRYAYVHDIFSNGVLLDKALVIYFKAPYSFTGEDVCEIQCHGSPLLAQNILQACLNLGARLAKAGEFSKKAFLNHKMDLSEIEASVQLILCEDESVLNALARQLKGELKIFIEEARGNLLKLLASSEVLIDYSEEDIPSDFLDGVSLNLEKQIASFKDLLDFSNAQKQRNKGHALSIVGKPNAGKSSLLNAMLLEERALVSDIKGTTRDTIEEVIELKGHKVRLIDTAGIRESADKIERLGIEKSLKSLENCDIILGVFDLSKPLEKEDFNLIDTLNRAKKPCIVVLNKNDLAPKLELEILKSYLKIPYTLLETNTLNSKACLKDLSQKISAFFPKLDTQNKLLLTSLAQKIALENAITELQNAKNHLETLELFSYHILSAIENLNLLTRPYETSQMLDSMFSEFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_LIGS1
Sequence: MEKGKVVLAYSGGLDTSVEIAWLKNKGYDVIACCIDVGEGKDLEAIKEKGLKVGAVESIVIDAKHEFAEEYVLPALQGHAYYENKYPLVSALSRPLIVKKLVEVAKEHGATAIAHGCTGKGNDQVRFEVGIHALVPEMKIEDPIRDLHWSREEEIEYAKENGIPVPISKKSPYSIDENLWGRANECGILEDPWQSAPADAYDRTVALEDTPDTPDVIEITFDKGVPTKLDGEELPLEELIMKLDKLAGKHGIGRIDHVENRLVGIKSREVYECPAATVLLAAHKDMEDLTHERDLAHFKPIIEQKLSELIYNGLWFSPLMDAIQAFLAETQKVVNGVVRVKLFKGNVICEGRKSPNSLYSEELATYTSADQFDQEAAAGFIKLWGLPTQVYAEVMQQNEKNNK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SYNAS
Sequence: MKTYQAKESEVAREWYLIDAEGQVLGRMASEIARRLRGKHKPEYTPHVDTGDFIVVVNAEKMVLTGKKLRDKIYYHHSGYPGGLKEKTAGKMMQEKPTDVLWLAVKGMLPKNSLGRRMLRKLKVYAGNDHRHEAQCPKVLPL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RBL_LUPDI
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLMM_LIMF3
Sequence: MKLKYFGTDGVRGVANRDLSPELAFRVGRAGGYVLTRHSQRKRPQVLVSRDTRISGEMLENALVAGLLSVGIEVFRLGVVTTPGVAYLVRAQEADAGVMITASHNPIQYNGIKYFGGDGFKLSDELEYEIEQLLDAEEDILPRPSDDGLGTVEDYREGALKYTSFLEQTISTDLDGLKVVIDGANGATSSFIANLFADVNADFIPLHVSPNGLNTNLNCGSTHPADLQKAVVENQADLGIAFDGDGDRCIAVDNEGNLVDGDKIMYICGKSMEANGRLKKDTVVTTVMSNLGMYKALESHGMKSVKTKVGDRYVVEEMLKNGYNLGGEQSGHIIFLDHNTTGDGMLTALQLLQVVKTSGKSLKELAADVVTYPQELVNITVEDKEAALNNQELKNAIAKVEEKMAGDGRILVRPSGTEPLLRIMAEAPTKELVHAYVSQIADVARQVLPGAK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: LYS9_ECOLX
Sequence: MKKITGIILLLLAAIILAACQANYIRDVQGGTVSPSSSAELTGLATQ
What is the function of this protein?
Lysis proteins are required for both colicin release and partial cell lysis.
What are the official names of this protein?
Lysis protein for colicin E9.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: IBTK_MOUSE
Sequence: MDAATPDCTSKCRSLKHALDVLSVVTKGSESQIKSFLARYCYNAATVKDAFGRNAGHLASSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSVFYGHIDCVWSLLKHGVSLYMQDKEGLSPLDLLMKDRPTHVVFKDTDPTEVYTWGDNTNFTLGHGSQNSKHHPELLDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLSGHNCSQVAAAKDHTVVLTDDGCVYTFGLNMFHQLGIIPPPASCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICVLAMDGAGRVFCWRSISSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKNSEKKADILPNLHHSSSDVSCVPDTNSVYERIRLEKLPFAHRAVSVSTDPSGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDSFHDVTFQVGNRHFPAHKYILAVRSDFFQKLFLSDGSSLELTDVYQKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDLLTHGFKPRMIVKRKAEDCEGSPDSHLHTVNCHVDDKQKSAFEVYRSNQAHTLSERQKSKPKSSKKGKGVGDDDPVRMLQSVAKKFGLSNLSSRLEGVRLENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFSCHKCVLCARLEYFHSMLSRSWIEASSCAALEMPIQSEILKVILDYLYTDEAVVIKESQNVDFVCSVLVVADQLLITRLKEICEVALTENLTLKNAAMLLEFAALYNAGQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISSMQVEDGEVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYTLSDVIQSPPSAGLLKSAKTNSVESLPELLTSDSEGSYAGVASPRDLQSPDFTAGFHSDKVEGKAKPYVNGIPPPCTREDVKPWEKSPTTKSAPQFIPSNRVDTAASSSWLAGSCSPVSPPVVDLRTIMETEENRQKYGAAPKSNLGKIISHGIKLSQKQRKMIALTTKENNSGTNSMEAILTAPSKSPKPANAWAPLHSPLSRSFRDFLLEEKKPVPGYGSGDHVKKVCFKGTENSPALNVARCSTHGTPGLESNHVSDFPLLDSPNPWQSSSLAASPAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPEEFVVVERAPQGPLAVPMWNKHGC
What is the function of this protein?
Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development.  Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription (By similarity).
What are the official names of this protein?
Inhibitor of Bruton tyrosine kinase, IBtk.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Translocates to the plasma membrane upon IgM stimulation.
Protein: TRPC_LACP7
Sequence: MILEKIVETTKDRINQEKRRLPEEVIKKSATEMAIKQGFGSSSSISRDKFFFEEVMSRPGVNFLCEIKRASPSKGMIAKDFDPVFIAKEYEEGGAAAISVLTEPTFFLGKDDYLMEVKKEVGIPVLRKDFILEAYQIYQAKLLGADCVLLIVSILTEEQLTGFLKICDELGLSALVETHNQEEVMRALQCGARIIGVNNRNLSTFEVSIENSLKLRTLVPKEAIFIAESGISTPEQIKELKEAGVNGVLIGETLMKASNKKLMIRNLKSLL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: KRA33_SHEEP
Sequence: ACCARLCCSVPTSPATTICSSDKFCRCGVCLPSTCPHTVWLLQPTCCCDNRPPPYHVPQPSVPTCFLLNSSQPTPGLESINLTTYTQSSCEPCIPSCC
What is the function of this protein?
In the wool cortex, wool keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant wool shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of wool keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin, high sulfur matrix protein, IIIB3.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 3 family.
Protein: YBEY_CHLT2
Sequence: MLILDRSSPQIFISNEQQDVSIDLQSAQRLVVLFLELQKVSTDQVYVYFLDDTALAQLHDEQFSDPSLTDTITLPIDKPGIASFPHVLGEAFVSPKAAMRFLEQYTEDQLYHEISRYVVHSLLHMLGYDDQTDEDKRIMQEQEDVSLSFLAEHQALLRPAV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_VIBPA
Sequence: MAPITFHLDVVSAEKRIFSGRVETFQVTGSEGELGIFHGHTPLLSAIKPGMVRIVKQHGHEEFIYVSGGMVEVQPGTATVLADTAIRGEDLDAAKAEEAKRRAEEKIQNQHGDMDFAQAASELAKAIAQLRVIELTKKRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VP4_ROTHK
Sequence: MASLIYRQLLTNSYSVDLHDEIEQIGSEKTQNVTVNPGPFAQTRYAPVNWGHGEINDSTTVEPILDGPYQPTTFKPLTDYWILINSNTNGVVYESTNNSDFWTAVVAVEPHVNPVDRQYTVFGENKQFNVRNDSDKWKFLEMFRGSSQNEFYNRRTLTSDTKLVGILKYGGRIWTFHGETPRATTDSSNTANLNDISIIIHSEFYIIPRSQESKCNEYINNGLPPIQNTRNVVPLSLSSRSIQYKRAQVNEDITISKTSLWKEMQCNRDIIIRFKFGNSIVKLGGLGYKWSEISYKAANYQYNYLRDGEQVTAHTTCSVNGVNNFSYNGGSLPTDFSVSRYEVIKENSYVYVDYWDDSKAFRNMVYVRSLAANLNSVKCTGGSYNFSIPVGAWPVMNGGAVSLHFAGVTLSTQFTDFVSLNSLRFRFSLTVDEPSFSILRTRTVNLYGLPAANPNNGNEYYEISGRFSLISLVPTNDDYQTPIMNSVTVRQDLERQLTDLREEFNSLSQEIAMSQLIDLALLPLDMFSMFSGIKSTIDLTKSMATSVMKKFRKSKLATSISEMTNSLSDAASSASRSVSIRSNISTISNWTNVSNDVSNVTNSLSDISTQTSTISKNLRLKEMITQTEGMSFDDISAAVLKTKIDMSTQIGKNTLPDIVTEASEKFIPKRSYRILKDDEVMEINTEGKVFAYKIDTLNEVPFDVNKFAELVTNSPVISAIIDFKTLKNLNDNYGITRIEALNLIKSNPNVLRNFINQNNPIIRNRIEQLILQCKL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: GAR1_CAEEL
Sequence: MSFRGGRGGGGGFRGGRGGGGGGGFRGGRGGDRGGGFRGGRGGFGGGGRGGYDQGPPEEVVLVGVFSHQCQDDIVCNNTSGKIPYFNAPIYFKNKEQVGKIDEIFGSPGENGFSVTLSQGVKASSFEPESQLYIDPGKLLPVDRFLPQAGGGRGRGGRGRGGDRGGRGSDRGGRGGFGRGGGGGFRGGDRGGFGGGRGGFRGGDRGGFRGGRGGDFGGRGRGDFKRSYDGGSFGGQNNKRTKFE
What is the function of this protein?
Required for ribosome biogenesis.  Part of a complex which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Probable H/ACA ribonucleoprotein complex subunit 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL23_CHLPM
Sequence: MKNPLLRPWLTEKSTGLTEDRGQYVFQVKLDADKIDIKMAVEEKFGVDVKSVRTLNSLGKTRRQNTRKGLVTGKKNDTKKAIVTLGEGQTIDFYSGANPKGDA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: VP5_IPNVJ
Sequence: MAKALSNKPTNILIYMNHEHIQGNRNLLEIHYASREWASKHSGRHNREAYTKTRDLVIQLRGIRIRKWASCLLPRSSWIQGRCPLQVESEPDGTRIRPVARDVTGPKEGIQLRETDLTEIRHPELNPSRWSVCTQWDPERCHLRRKSV
What is the function of this protein?
VP5 is not required for viral replication in vivo and its absence does not alter the virulence characteristics of the virus or the establishment of persistent IPNV infection.
What are the official names of this protein?
Protein VP5.
What is the protein family that this protein belongs to?
Belongs to the avibirnavirus/aquabirnavirus VP5 protein family.
Protein: PUR5_LISMC
Sequence: MAENAYSKAGVDVEAGYQVVERIKKHVARTERLGAMGALGSFGGMFDLSSLHLKEPVLVSGTDGVGTKLLLAIEADKHDTIGIDCVAMCVNDILAQGAEPLFFLDYIATGKTDPVKMEQIVKGVADGCEQAGAALIGGETAEMPDMYGAEDYDLAGFTVGAVEKQKLITEGAVKEGDTLIGIPSSGIHSNGYSLVRKIFFKDNELTLDAEISELDVPLVEELLKPTRIYVKPVLEVLKEVDVHGITHVTGGGFVENLPRMLTNDLAVKVELGSWPVLPIFDVMKKYGQLSELEMYEIFNMGIGMVLAVAKADVERTLEVLVQNGEAAYVIGEVTTRENDAVIFTGGTKG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSI3_ORYSJ
Sequence: MALASLPKVVMGSVAFGVFWMLAVFPSVPFLPIGRTAGALLGAVLMIVFHVISADDAYASIDLPILGLLFATMVVGGYLKNAGMFRHLGRLLAWRSQGGRDLMCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALATSANIGSSATPIGNPQNLVIAFNSKISFISFLLGILPAMLAGMGINMLMLLCMYWKELDGGACSPDEVAAGKQMEAIEEGRRTALNNNKKDDGDAATPASPEDDDGGDAESMMSENISTKHRWFMQCSEHRRKLFLKSFAYVVTVGMLVAYMLGLNMSWTAITTAIALVVVDFRDAEPCLDKVSYSLLVFFSGMFVTVSGFNKTGLPGAIWNVMAPYSKINHVTGVTVLSVIILLLSNLASNVPTVLLMGDEVAAAAATISPAAVTRSWLLLAWVSTVAGNLSLLGSAANLIVCEQARRATRNAYDLTFWNHVIFGLPSTLVVTAIGIPLIGKINI
What is the function of this protein?
Silicon efflux transporter involved in silicon transport in shoots.  In the nodes, involved with LSI2 and NIP2-2/LSI6 in silicon intervascular transfer, which is required for the preferential distribution of silicon, such as hyperaccumulation of silicon in the husk.  Silicon is beneficial to plant growth and helps plants to overcome abiotic and biotic stresses by preventing lodging (falling over) and increasing resistance to pests and diseases, as well as other stresses.
What are the official names of this protein?
Silicon efflux transporter LSI3, Low silicon protein 3.
What is the protein family that this protein belongs to?
Belongs to the arsenite-antimonite (ArsB) efflux (TC 2.A.45) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATB_COXBR
Sequence: MEWEPVIGLEVHVQLRTQSKIFSGAATAYGAEPNTQACAIDLGLPGVLPVLNKEAVKLAVCFGLSVNASIPPYSIFARKNYFYPDLPKGYQISQYNFPIVQNGHLDIENEDGTTKRIGITRAHLEEDAGKSFHEGMQGYSGIDFNRAGTPLLEIVSEPDIRSAQEAVAYLKALHSLVRYIGVSDANMQEGAFRCDVNISLRPKGEEKFGTRAEIKNVNSFRFVERAILFEINRQKEILENGGTIVQETRLYDAVQDETRSMRTKEEAHDYRYFPDPDLLPVEIGPEFIEAVKNQLPELPWEKRKRFAASYQLSNYDVKLLTTQIEIANYFETVLKIDKTIPPKLAANWINGDLAAALNKNNLSITQSPINAEQLAGLLHRIADNTLSGSMGKQVFETMWGGEGDADTIIERHGLKQITDTEALEKIIDEVIENNPTQVEQYRSGKDKLIAFFVGQVMKATKGKANPQQVNELFKKKL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: DXR_PSEAB
Sequence: MSRPQRISVLGATGSIGLSTLDVVQRHPDRYEAFALTGFSRLAELEALCLRHRPVYAVVPEQAAAIALQGSLAAAGIRTRVLFGEQALCEVASAPEVDMVMAAIVGAAGLPSTLAAVEAGKRVLLANKEALVMSGALFMQAVKRSGAVLLPIDSEHNAIFQSLPRNYADGLERVGVRRILLTASGGPFRETPLEQLASVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAQPSQVEVVIHPQSVIHSMVDYVDGSVIAQLGNPDMRTPISYAMAWPERIDSGVSPLDMFAVGRLDFQRPDEQRFPCLRLASQAAETGGSAPAMLNAANEVAVAAFLERRIRFSDIAVIIEDVLNREAVTAVESLDQVLAADRRARSVAGQWLTRHAG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.