PharMolix/UniProtQA huggingface dataset:
Protein: DRE2_BLAGS
Sequence: MASTGRVLLLSPPSLSSHPEKLNAILGSHTRDRTDLQMLDRLVHGLVSLPASTYDIVLLLTGADNTLAEPYSLVTRDIIQQVVHSLKPAGKLRSQDNKAWGLRSSGNNSDDDNDNDELTFRNEAILAGLVFDDNGELLKPDVAAQQAVPLKLGRRKKEKERRHPSGNDVTNGKVNAPSSNGVNASTSTATATATTTTTTTPKTNPAPSGVGFIDFSDDYGVPMEEDPQGSDDELIDEDELLGEDDMGRPIVQPPECRPKPGKRRRACKDCSCGLSQKLEAEDKAKRATADKALETIMAPTMKLGSSELAEVDFTVQGKVGSCGNCSLGDAFRCDGCPYIGLPAFKPGEEVRLLNNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: SYP_AFIC5
Sequence: MRLTRYFLPILKETPKEAEIASHRLMLRAGMLRQEAAGIYAWLPLGFRVLKKIERIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIADRHKRELLYGPTNEEMITEIFRSYVKSYRNLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDLDEAAARLSYNKMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEFIVLAETGESGVFCNKDVLDLPVPGEDVDYDSDLTPIIKQWTELYAATEDVHDAARYETEVPAEKRVNTRGIEVGQIFYFGTKYSDSMKALVVGPDGVEKPVHSGSYGVGVSRLVGAIIEACHDENGIKWPEAVAPFTVAILNLKQGASDTDAACEKLYRALTANGVDVLYDDTDQRPGGKFATADLIGIPWQILIGPKGLAEGKVEIKCRADGSRELMSPEDALARFGAKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_HELMI
Sequence: MEAKDRLIVALDVDTRDEAISIVNAVGEHCGLFKVGMQLHNSAGFAVTEEILSMGFPVFLDLKFHDIPNTVGKAATVVSRRGVKMFTVHAAGGREMLRQAVKGAREGQGERRSGGPLVLAITVLTSVSQAVLHDEVGLPGSVEENVVRFARLAQAAGVQGVVASPQEIRPIRAACGDDFVIVTPGVRPLWAGTDDQARIMTPAKAMEAGATYLVVGRPITAAPSRAEAAKRIVEEMAEGLARR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: STEA4_MOUSE
Sequence: MEKAHADEFPLTTDSSEKQGVVCIFGTGDFGKSLGLKMLQCGYSIVFGSRNPQVSSLLPRGAEVLSYSEAASKSDIIILAMHREHYDSLTELVDYLKGKVLVDVSNNRKINQYPESNAEYLAQLEPGAHVVKAFNTISAWALQSGTLDASRQVFVCGNDSKAKQRVMDIARTLGLTPLDQGSLMAASEIENYPLQLFPMWRFPFYLSSVLCVFFFVYCAIREVIYPYVNGKTDATYRLAISIPNRVFPITALILLALVYLPGILAAILQLYRGTKYRRFPNWLDHWMLCRKQLGLVALGFAFLHVIYTLVIPIRYYVRWRLRNATITQALTNKDSPFITSYAWINDSYLALGILGFFLFLLLGITSLPSVSNMVNWREFRFVQSKLGYLTLVLCTAHTLVYGGKRFLSPSILRWSLPSAYILALVIPCAVLVLKCILIMPCIDKTLTRIRQGWERNSKYTQSALNGKSDI
What is the function of this protein?
Integral membrane protein that functions as NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane (PubMed:16609065).  Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate (By similarity).  Can also reduce Cu(2+) to Cu(1+) (PubMed:16609065).  Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (PubMed:17482547).  Associated with obesity and insulin-resistance (By similarity).  Involved in inflammatory arthritis, through the regulation of inflammatory cytokines (PubMed:19660107).  Inhibits anchorage-independent cell proliferation (By similarity).
What are the official names of this protein?
Metalloreductase STEAP4, Dudulin-4, Six-transmembrane epithelial antigen of prostate 4, Tumor necrosis factor-alpha-induced adipose-related protein.
What is the protein family that this protein belongs to?
Belongs to the STEAP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: MAFB_XENLA
Sequence: MAGELPIATPLPTSPLAMEYLNDFDLMKFDVKKEPLGGRPDRAIRQCNRLQPTGSVSSTPISTPCSSVPSSPSFSPTEHKTHLDDLYWMSSSSYQHVSPEALNLTPEDAVEALIGQHQMPPQLQGYESFRAHHHHHHQNQHQYQGVHHEEMGLPHHHPHHHQHQHHQTSPSPSGSSSSSQQLHHQQQHSSSSAVEDRFSDDQLVSMTVRELNRHLRGFTKDDVIRLKQKRRTLKNRGYAQSCRYKRVQQKHNLEGEKTQLVQQVEQLKQEVSRLARERDAYKIKCEKLANNNSSNFREAGSTSDNPSSPEFFM
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Implicated in the regulation of cell-type specific gene expression and play a role in inductive events during lens development.
What are the official names of this protein?
Transcription factor MafB, Maf-B, XMafB.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAA_PELTS
Sequence: MSSENKKEPLLVITGPTATGKSEVGVLVAEKLGGEIISADSMLIYRGMDIGTAKPTSADRRGIPHHMIDIVEPDQDYNVALYRKQAMAVIKKVLERGNLPIVVGGTGLYIEALIRNYSFGGAGTDKTLRKKLQKEAAESPFLLHQRLAKIDPATASQLHPANTRRVIRALEVYYLTGKPISNFKRLDEPDPPFNLLMFGLTMEREALYRRIEKRVDRMIAMGLIEEVQNLLQRGFSPRLNSMRGLGYKEMISYLNGTLSLEEAVEVLKRNTRRFAKRQMTWFRRYKEIRWLKIENFADCEAIAQEIARCTEGVL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL34_TREPS
Sequence: MKRTYQPSRRKRVRKFGFRARMATRGGRAILRRRRAKGRRKLTVSDEKKPY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: FDHL_STAAB
Sequence: MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGPIQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVCDYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDIEVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMTDTEPGSLAAMVDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVWTKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEALNVIADNFTSIKEKYGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQAPATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIHVFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIEEWVEDFDEYYKSLETFTMAFAEEATGIPEAELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNLLLVTGNYRRPSTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVKLNPKVGKDNHEMVEGVHDGEIHSLYLYGEDTGIVDSNINFVQAAFENLDFMVVQDEFLTFTATFADVVLPASPSLEKDGTFTNTERRIQRLYQALKPLGESKPDWKIFQAIANKLGFDWNYKHPSEIMDEIARLTPLYAGVSYERLEGFNSLQWPVHPDGTDEPILYLEGFNFDNGKAKLFPLSFDNYFKQDEVYDIHVNNGRLLEHFHEGNMTYQTPMIKYKVPRAFVEISPELAEDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINLLTNSDVDQYTDTPSYKRTSCRLEVIAKRGKSPLNPNNFRVNKKRHPQYSVQVQKKWERPDYVFPGNQVDK
What are the official names of this protein?
Putative formate dehydrogenase SAB2186c.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: S12A6_HUMAN
Sequence: MHPPETTTKMASVRFMVTPTKIDDIPGLSDTSPDLSSRSSSRVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKKKPTKTPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLQAFAIVLICCCCTMLTAISMSAIATNGVVPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFHSDDALKESAAMLNNMRVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPVCMLGNRTLSSRHIDVCSKTKEINNMTVPSKLWGFFCNSSQFFNATCDEYFVHNNVTSIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGSLNHEYVLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKANGEPTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLACALQTLLRTPNWRPRFRYYHWALSFMGMSICLALMFISSWYYAIVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARFALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKHPRLLTFASQLKAGKGLTIVGSVIVGNFLENYGEALAAEQTIKHLMEAEKVKGFCQLVVAAKLREGISHLIQSCGLGGMKHNTVVMGWPNGWRQSEDARAWKTFIGTVRVTTAAHLALLVAKNISFFPSNVEQFSEGNIDVWWIVHDGGMLMLLPFLLKQHKVWRKCSIRIFTVAQLEDNSIQMKKDLATFLYHLRIEAEVEVVEMHDSDISAYTYERTLMMEQRSQMLRHMRLSKTERDREAQLVKDRNSMLRLTSIGSDEDEETETYQEKVHMTWTKDKYMASRGQKAKSMEGFQDLLNMRPDQSNVRRMHTAVKLNEVIVNKSHEAKLVLLNMPGPPRNPEGDENYMEFLEVLTEGLERVLLVRGGGSEVITIYS
What is the function of this protein?
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:16048901).  May contribute to cell volume homeostasis in single cells (Probable).
What are the official names of this protein?
Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein.
Protein: BLO10_PSEAI
Sequence: MKTFAAYVIIACLSSTALAGSITENTSWNKEFSAEAVNGVFVLCKSSSKSCATNDLARASKEYLPASTFKIPNAIIGLETGVIKNEHQVFKWDGKPRAMKQWERDLTLRGAIQVSAVPVFQQIAREVGEVRMQKYLKKFSYGNQNISGGIDKFWLEGQLRISAVNQVEFLESLYLNKLSASKENQLIVKEALVTEAAPEYLVHSKTGFSGVGTESNPGVAWWVGWVEKETEVYFFAFNMDIDNESKLPLRKSIPTKIMESEGIIGG
What is the function of this protein?
Hydrolyzes both carbenicillin and oxacillin.
What are the official names of this protein?
Beta-lactamase OXA-10, Beta-lactamase PSE-2.
What is the protein family that this protein belongs to?
Belongs to the class-D beta-lactamase family.
Protein: CERS4_MOUSE
Sequence: MSFSLSEWLWQETYWLPPNVTWAELEDRDGLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYHESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVKRKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTRLIFFPTQVIYTSVYDSIKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEPVSEGPQLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT
What is the function of this protein?
Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.
What are the official names of this protein?
Ceramide synthase 4, CerS4, LAG1 longevity assurance homolog 4, Sphingosine N-acyltransferase CERS4, Translocating chain-associating membrane protein homolog 1, TRAM homolog 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL3_CLOBK
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPVKGHFAKAGVSVKRHIKEFKLEDSNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVKIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y2356_VIBA3
Sequence: MYPNLTGLGIHEPKQIERYSLRQEAHKDILKIYFRKQKGELFAKSVKFKYPRQVKSVLVSGGNNQYKEVTEINRNLTLVIDELNKITKPTPTAEVDLKQKILTDLRHLEKVVSSKIAEIEVDLEKLK
What are the official names of this protein?
UPF0325 protein VS_2356.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: MURA_PROM9
Sequence: MICGSKKKAYLKSQNLKILGQGKLNGIVKINGAKNSALVLLASSLLTNEKIILENIPYLTDIEKMGNILKNLGVNLIDKNDQLEIDPTNISIKELPYELVNGLRASFFCIGALLTKFGEAQVPLPGGCNIGSRPIDEHINGLIALGADIIIEEGIVKAKIRGNKNKLHGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCHMLNKMGAKIYDSGKETIIIDGVNKLGGCTHKVIPDRIEAGTFLIAAAATSSSITISPVIPHHLEAVTNKLQESGSKITIKGNSISIKSKEIKGVDIETAPFPGFPTDLQAPFTALMTIANGESKITETIFENRMNHIHLLNKMGARIKLNENVAYIKGVKTLNGMDLIGSDLRSSAALIIAGIIAEGTSNIYGLEHLDRGYENFELKLKKLGIKITREFNKSTFEENEFKIEPKSEDISNLRAA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THMYZ_THETS
Sequence: MHAKIILALFLGMTAFLAVQADHHHDHGHDDHEHEELTLEKIKEKIKDYADKTPVDQLTERVQAGRDYLLGKGARPSHLPARVDRHLSKLTAAEKQELADYLLTFLH
What is the function of this protein?
Has bacteriostatic activity against M. luteus.  No activity toward E. coli and F. oxysporum.
What are the official names of this protein?
Theromyzin.
Protein: ATTY_TRYCR
Sequence: MSSWDVSMSNHAGLVFNPIRTVSDNAKPSPSPKPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGYFPTVGSPEAREAVATWWRNSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYGIGMHFYNCRPENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLGWLLYVDPHGNGPSFLEGLKRVGMLVCGPCTVVQAALGEALLNTPQEHLDQIVAKIEESAMYLYNHIGECIGLAPTMPRGAMYLMSRIDLEKYRDIKTDVEFFEKLLEEENVQVLPGTIFHAPGFTRLTTTRPVEVYREAVERIKAFCQRHAAV
What is the function of this protein?
Transaminase involved in tyrosine breakdown.  Converts tyrosine to p-hydroxyphenylpyruvate (By similarity).
What are the official names of this protein?
Tyrosine aminotransferase, TAT, L-tyrosine:2-oxoglutarate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Mainly cytoplasmic. Present to a small extent in the mitochondrial fraction.
Protein: LEU3_NITMU
Sequence: MKIAILAGDGIGPEIVAQAVRVLETLRSDGLKLELEQGLLGGCAVDAAGEPFPAATRTLVAQADAVILGAVGGPRYDGLPRQLRPEQGLLGIRKALNLFANLRPAVLYPELADASTLKPEVVSGLDILIVRELTGDIYFGEPRGIELRNGQRIGYNTMIYSEAEIRRIARVAFQAARKRSRRLCSVDKMNVLESTQLWRDVVTETAGEYPDVELSHMLVDNAAMQLVRNPRQFDVVVTGNMFGDILSDEASMLTGSIGMLPSASLDERNKGLYEPIHGSAPDIAGKDVANPLATVLSVAMMLRYTFDREEEASRIERAVKKVLADGYRTADIYEPGKMKIGTAAMGDAVLASL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_LOLPR
Sequence: MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGSGGAIRKKEATHRMAEANRALAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPXH_EDWI9
Sequence: MATLFIADLHLSQQEPAITAGFLRFLAEEAPKAEALYILGDFFDYWIGDDDPQPLHRQVAGALRQLSDNGVPCYFICGNRDFLLGKSYAKRCGMTLLPDEQIITLYGQPILLLHGDTLCSDDRDYQRYRRRVHNPLLQWLFRRLPLRLRLKIAVGMRQQSQRSNSAKAMTIMDVNQETVCATLRRHGVQRMIHGHTHRPALHHFSLDDGRCALRAVLGAWHTHGSMIRVDAQGIHLIELPAHPAEDEIITTRLRSANLV
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TPM1_CAEEL
Sequence: MDAIKKKMQAMKIEKDNALDRADAAEEKVRQITEKLERVEEELRDTQKKMTQTGDDLDKAQEDLSAATSKLEEKEKTVQEAEAEVASLNRRMTLLEEELERAEERLKIATEKLEEATHNVDESERVRKVMENRSLQDEERANTVEAQLKEAQLLAEEADRKYDEVARKLAMVEADLERAEERAEAGENKIVELEEELRVVGNNLKSLEVSEEKALQREDSYEEQIRTVSSRLKEAETRAEFAERSVQKLQKEVDRLEDELVHEKERYKTISEELDSTFQELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction (PubMed:9113409, PubMed:11901171).  Involved in muscle actin filament organization and muscle arm extension and morphology (PubMed:15930100).  Protects actin filaments from depolymerization by unc-60 in vitro (PubMed:17684058).  Also has a role in male mating behavior by regulating the copulatory spicules (PubMed:16399684).  Binds to F-actin (PubMed:11901171).
What are the official names of this protein?
Tropomyosin isoforms a/b/d/f, Levamisole resistant protein 11.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: FTHS_HALMA
Sequence: MEPIWELVEPWGLGLDDLQYFGEYTAKVKQHAIERLREQAENREQNLVLVTGMTPTPKGEGKTVTTVGLGQTLNHVGEEAMIAIREPSLGPVFGVKGGAAGGGRSQVLPMEDINLHFTGDLHALTSAHNLIAAMLDAKISQGDDLNIDINNVSWPRAIDMNDRALRETVVGLGGKTGGTPREDSFILTAASELMAVLCLASDIGDLKERVSRIIVAYDEDGDPVTVEDIEATGPATMLLRDAIKPNVVQTIEGTPALVHGGPFANIAHGTNSLVADKTAFGMGDYLVTEAGFGSDLGAEKFMDVVCRKGDMTPNAVVLVASVRALKYHGLNQWPVDYDEIGEAGVEAVEAGFSNLDKHARNLQKFGVPVVVSVNRFPDDTDEEVQAVLDHCREDLGVRAAESNVFSDGSEGGVDLAENVIEATEESNEEDFRMLYDDDDSIKEKIHTVATEIYGADDVKYTGGALDDIEQMNDLDFDDYPVVMSKTFHSLSDDASQKGAPEGWELEISEVYPSAGAGFLVALTADALTMPGLPARPAAADMDIDGDGNISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: SCNNA_PELSI
Sequence: MHQVVTVKAEKVPMGKRLRRCKQEAENQQKVEEVAEKLEKEHEGLIEFHKSYHELFQFFCNNTTIHGAIRLVCSKRNKMKTAFWSVLFFLTFGLMYWQFGILYREYFSFPVNLNLNLNSDKLTFPAVTLCTLNPYRYSAVRKELDELDRITHQTLMDLYNYSMSQVQSNGAAQSSQKRSQRSLSHHVQRHPLRRRKRNEPVSLKGNSPPVDKSDWKIGFILCNETNEDCFHQTYSSGVDAVREWYSFHYINILARMPDTKALDESNFESFIYACRFNEVTCDKANYTHFHHPLYGNCYTFNDRNNSLWTSSLPGINNGLSLLVRTEQNDYIPLLSTVTGARVMVHEQNEPAFMDDGGFNVRPGIETSISMRKETTMLLGGSYSDCTEDGSDVPVQNLYSSRYTEQVCIRSCFQIHMVKRCGCAYYFYPLPPGAEYCDYTKHIAWGYCYYKLQVEFKSNILGCFSKCRKPCEVTKYQLSAGYSHWPSAVSENWVFHILSQQNKYNITSKRNGVAKVNIFFEEWKYKTNGESPAFTVVTLLSQLGNQWSLWFGSSVLSVVELAELILDFIAITIILSFKRFRSRQVPAPSVPPPGAHDNTAFQSEPADPSAPHRFTVEAVVTTLPSYNSLEPCRRDGEAVIGLE
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1A subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cytoplasmic granule. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
Protein: ARGB_PECCP
Sequence: MNPLIIKLGGVLLDSEEALERLFTALVAYRQEHQRPLVIVHGGGCLVDDLMKKLSLPVVKKNGLRVTPADQIDIITGALAGSANKTLLSWAKKHDINAVGLCLGDGGSTTVTQLDEALGFVGKAEAGSPALLNTLLSAGYLPVVSSIGITAQGDLMNVNADQAATALAQTLGADLILLSDVSGILDGKGQRIAEMTAEKAEQLIAQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGVAIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRLL_DICDI
Sequence: MKLIIKNLILLLVSCLYFLSNVSCDQEVHMALLLEGQVDDLGINYEVNQGLAETEALIQRAAKVINDANSYDSTYDNIKSLLDQDNPYNLIITSSESQMSAALDIASDYEDTYFLIFGDMGDKKVPHSKVGTYYFNLVSPHFVLGFIAGGMGKSVGMVVPGPPTENYFTANAFYAGMKYYTSPAGAPNPSLSVVATSSYDDYDTATGAGRILLTKDIDICTQSQTDMTVANMFLNASKWAFGTNGFPQSNIYGNRIIQSVVHNFQVPFYEAATMVMKNTWKNGYNFFGDFNNNFFYLDYYSFLVDPLLKNQTEDLISTIKGGAKPYITNGLTYEKILEQTKLSTGITDLGYYAVPTTEVYTTGSINKTFMAVSILEMAICLIIGIIVIFFFSRNINIIYSTIPYCLTILLGASLIAVAIFLWNLRDLNTQICTSKIWMASLGYNVLIGFIIIKSSLIYFKFKEMVKSKNEKISPIPFGRIVLWFVPLLIIDCVLLIIYSTSGNPGKIDSLGLDGIGRYEYTQNCVNNLTGDIILYIILVFHGLQLLYGCVIAWKTRVIDLEEFIEAHDFATAIYLITFCSFIIVILMVGVTSTSNRNTIISACAIFSSFSCVLIIFGAKFWKIYKPVEDDGLPQIKLKPQKSYSGSGGSGNSSGSKSKKTSAHSSTSGVKSGTSAPTQTSQSAMASINIQNFVNPIEASSRAAAQNDN
What are the official names of this protein?
Metabotropic glutamate receptor-like protein L.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYY_BRUSU
Sequence: MSGFKSDFLRTLSERGFIHQISDESGLDELLAKETVTAYIGFDPTAPSLHAGGLIQIMMLYWLQQTGHKPVALMGGGTGMVGDPSFKDEARKLMTEDTIAENMASIKRVFANYLTFGDGANDALMVNNGEWLRNINYLEFLRDVGRHFSVNRMLSFDSVKLRLDREQSLSFLEFNYMILQAYDFVELNKRYGLRLQMGGSDQWGNIVNGIDLGHRMGTPQLYALTSPLLTTASGQKMGKSLGGAIWLNADMLSAYDFWQYWRNTEDADVERFLKLYTTLPLDEIARLAELGGAEINEAKKILATEVTAMLHGRDAAEEAAETARKTFEDGELSENLPTVGVHKATLNDGIGVLALMVLAELCTTNGEARRHVEGGAVRINDEPVSDPRMVVNAAALNGQGLIKLSLGKKRHVLIRPA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCA1_YARLI
Sequence: MHRTSIVEELERHQQDQKADQEPGSVSDASNSALQESSDPRLSTTDNTNTPEINVNDQQQEQQVASGEDTDPPSPRMKTIVKPPPIKVVPPLNFGPVERNLYRSGQPEPISFPFLEKLRLRTILWLAVEDPSDNFLAFADDHEIVVHHLGLVTEGTNPWDQLTESSIVAALQIIMDRDSYPLLVCCGMGRHRTGTIVGCLRRLQGWNLASVSEEYRRYAGSRGGRALIELHIEAFDTSRIIVYPESAPEWCSS
What is the function of this protein?
Putative tyrosine-protein phosphatase required for protection against superoxide stress.
What are the official names of this protein?
Putative tyrosine-protein phosphatase OCA1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.