PharMolix/UniProtQA huggingface dataset:
Protein: COAE_NOSS1
Sequence: MTQRIIGLTGGIATGKTTVANYLASAHNLPIFDADIYARDAVSLGSPILDAIARRYGKEILLPDGSLNRPKLGEMIFQNQDQRHWVESLIHPYVRDRFLKAIAESTSPILVLVIPLLIEVQMTNLVTEIWVVICSESQQLQRLMERNHLTLEQAQARINSQLSLKEKAAIADVVLDNSSSLDALLKQVDIALNFEL
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNT1_MACFA
Sequence: MGCWGRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERFVEPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHHSGFSQDSGHSHSHGSHGHGLPKGPRVKSSRPGSNDINVAPGEQGPDQEETNTLVANTSNSNGLKLDPADPEKPRSGDTVEVQVNGNLIREPDHVELEEDRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAFVEIINSTHASVYEAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNLIKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTSYMEVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTLPQAHSGKDAEKTPTVSISCLELSNNLEKKPRRTKAENIPAVVIEIKNMPNKQPESSL
What is the function of this protein?
Zinc ion:proton antiporter that could function at the plasma membrane mediating zinc efflux from cells against its electrochemical gradient protecting them from intracellular zinc accumulation and toxicity (By similarity).  Alternatively, could prevent the transport to the plasma membrane of CACNB2, the L-type calcium channels regulatory subunit, through a yet to be defined mechanism.  By modulating the expression of these channels at the plasma membrane, could prevent calcium and zinc influx into cells.  By the same mechanism, could also prevent L-type calcium channels-mediated heavy metal influx into cells (By similarity).  In some cells, could also function as a zinc ion:proton antiporter mediating zinc entry into the lumen of cytoplasmic vesicles.  In macrophages, can increase zinc ions concentration into the lumen of cytoplasmic vesicles containing engulfed bacteria and could help inactivate them (By similarity).
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A1, Solute carrier family 30 member 1.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPA_MAGMM
Sequence: MFKGVYTALITPFKNRAVDYTALAKLVEQQINGGIHGLVPCGTTGESATLSHEEHKAVIRTVVELVQGRVKVLAGTGSNCTEESTELTCYAEEVGADGALLITPYYNKPTQAGLIAHYTTVANHTKLPVVLYNVPGRTAVDMHADTVIALSKVSNIVAIKEATGNMERASQIHKGAGSSMTLISGDDATFLPFLSVGGQGVISVTTNLAPRLVRDLWDLWHNGQINEAREVHEQLLEINGLLFCETSPIPVKAGAAMLGLCHNELRLPMTAMSEANQAKLHRAMVKLNLLEE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_SHESH
Sequence: MFLAQEIIRKKRNAEALSKEEIQFFVKGITDNTVSEGQIAALGMAVYFNDMNMDERIALTTSMRDSGTVLNWKSLDLDGPIIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYQTEPDSALFRKVVKEAGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLAAGLDALAMDVKVGSGAFMPTYEASEELARSITAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAVDFLTGAYRNPRLYEVTMGLCAEMLQLGGIASSEAEAREKLNRVLDNGKAAEIFGRMISGLGGPADFIENTGLYLPESKIIRPVYADQTGFASAMDTRELGLAVVTLGGGRRKPGDALDYSVGLTKVCALGDEISADKPIAFIHAQTENAFAEAEAAVKKAIHVGETKPEKTPEIYRYIRESDL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: ESXQ_MYCBO
Sequence: MSQSMYSYPAMTANVGDMAGYTGTTQSLGADIASERTAPSRACQGDLGMSHQDWQAQWNQAMEALARAYRRCRRALRQIGVLERPVGDSSDCGTIRVGSFRGRWLDPRHAGPATAADAGD
What are the official names of this protein?
ESAT-6-like protein EsxQ.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: PIR3_YEAS1
Sequence: MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSSSFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQVQAAKSTAAAASQISDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKDANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC
What is the function of this protein?
Component of the outer cell wall layer.  Required for stability of the cell wall and for optimal growth.  Required for resistance against several antifungal and cell wall-perturbing agents (By similarity).
What are the official names of this protein?
Cell wall mannoprotein PIR3, Covalently-linked cell wall protein 8, Protein with internal repeats 3.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently attached to the cell wall.
Protein: ATP7B_SHEEP
Sequence: MERAGDQAPGNPEPSSLATLGDPQVTLLTVHKRWSFKRSPGTGGSSRPVISEEECPPPSEEGEFSQKVLNGSEEISSKQILSKLFQPAMKQSFAFDNNGYEDDLDGVCPSQTAAGTISIVGMTCQSCVKSIEGRVSSLKGIVSIKVSLEQSSAEVRYVPSVVSLMQICHQIEDMGFQASVAEGKATSWASRVSPTSEAVVKLRVEGMTCQSCVSSIEGKIGKLQGVMRVRVSLSNQEAVITYQPYLIQPQDLRDHITDMGFEAVIKNKVAPVSLGPIDVRRLQSTLSVAPPAPVNQNDNNSETPGGQGVPLHLRVDGMHCKSCVLNIEDNIGQLPGVQSIHVSLESRTARVQYNPSLVSPGALRRAIEALPPGNFKVSFPNGAEGSGPDSRTPPAPSAPCTMMLAIAGMTCKSCVQSIEGLISQRVGVHQISVFLAEGTAVVLYDPSRTHPEELRAAVEDMGFEASILAENCSSNQVGNHSAGSAVGPEAAGAPVPMQGEAPQPGGLHTNHIPHQSPKSLLASTTVAPKKCFLQISGMTCASCVSNIERNLQKEPGILSVLVALMAGKAEVKYNPEAIQPLEIAKLVQDLGFEAAVMEDYTGSDGDLELMITGMTCASCVHNIESKLRRTEGITYASVALATSKAHVKFDPEIIGPRDIVKLIEEIGFRASLAQRIPNAHHLDHKVEIKQWKNSFLCSLVFGIPVMGLMIYMLIPSHEPQSSVLDHNVIPGLSILNLIFFILCTFVQFLGGWYFYVQAYKSLRHGMANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHVVKSKTSEALARLMSLQATEATVVTLGEDNVIIREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSMVIAGSMNAHGSVLITATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTVTLVVWIVIGFIDFGVVQKYFPAPSKGISQAEVVLRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPKVSRVLLLVDLATLPLRKVLAVVGTAEASSEHPLGVAVTRYCKEELGTETLGCCMDFQAVPGCGISCKVSSVESILAQGERLQGPPTAHQNRVGSEPSETDAATQTFSVLIGNREWMRRNGLTVTSDVRDAMTDHETKGQTAILVAIDGVLCGMIAVADSVKQEAALAVHTLKSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNQGKRVAMVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSRRTVWRIRLNLVLALIYNLIGIPVAAGVFIPIGVVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPDLARYEAQAHGHMKPLSASQVSVRVGMDDRRRDSPRASAWDQVSYVSQVSLSPLKSDKLSRHSGAADDRGDKWSLLLNDRDEEQGI
What is the function of this protein?
Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
What are the official names of this protein?
Copper-transporting ATPase 2, Copper pump 2, Wilson disease-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome. Note=Predominantly found in the trans-Golgi network (TGN). Not redistributed to the plasma membrane in response to elevated copper levels.
Protein: Y4526_NOCFA
Sequence: MGMRPPSGLPSLSRRSRVLLVAAVVLAALLLLGPRFTDAYTNWLWFGEVGFREVFLTVVVTRIILFAAVALFVGATVWLALLLAYRTRPVFVPMAGPNDPIARYRTTVMSRLKTFGIGIPVLLGLLAGLVAQSNWVTVQLFLNGGDFGEQDPQFHLDVGFYAFDLPFYRMVLNWMFVAVVIAFFASLVTHYIFGGLRLSGREGTLTRPARIQLAVIAGLFVLLKAVAYWFDRYDLLSSSRKEPTFYGGSFTDINAVLPAKLILLAIAVICAVAFFAGVVLRDLRVPAMAAALLVLSSVLVGAVYPLVVEQFSVRPNAADKESEYIERNIAATRQAFGITSDKIEYKDYKGESDKNPLDVPVDAATIGNARLLDPNILSPTFTQLRQLKNFYGFPESLDIDRYNLDGNLQDYIVAARELSPAALTGNQTDWINKHTVYTHGNGFVAAPANRVNKPQSEDVAAGGSSDSGYPIFLVSDLFTPKDRQRIPVEQPRIYFGELISQSDPDYAIVGGAEGQAPREYDSDTAQYTYTGKGGVPIGNWFNRLAFAAKYAERNILFSSAIGDDSKIIFNRSPRERVQKVAPWLTTDGNAYPAVVDERIVWIVDAYTTLDNYPYAQKTSLEGAVEDSIDKKTGRLLPRKEVSYIRNSVKATVDAYDGTVTLYEVDSTDPVLKAWRGVFPGAVKPESEISPELRAHFRYPEDLFKVQREMLTKYHVDNPREFFTNNAFWSVPSDPTIEGGSFNQPPYYVLLGDPKTNRPVFNLTSAMVGYNRQFLSAYISVRSDPDDYGKFTILRLPTDTQTQGPQQTQNTMTTAPQVSQEKTLLSNSNKIRYGNLLTLPIADGGILYVEPFYNERNTGPNTATFPQLLRVLVSYRDQAGSVKVGYASTLAEALNQVLPGAGSLATPFGGDPATRPQPGTAPPVVDSTQPPADGGTPQPQTTPPPTGSAAKDAAAAELDRKIEAVRNAMRSGNFQDFGKALEELEAAVKTYQDAGR
What are the official names of this protein?
UPF0182 protein NFA_45260.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_NOSS1
Sequence: MARDYYEILGVARDADKEEIKQAYRRLARKYHPDVNKEPGAEERFKEINRAYEVLSEPETRARYDRFGPEGVSGAGVGFQDMSDMGGFADIFESIFSGFAGGGMGGPTQQRRRGGPARGDDLRLDLKLDFREAVFGGEKEIRISHLETCETCSGSGAKPGTRPRTCSTCSGSGQVRRVTRTPFGSFTQVSTCPTCNGTGMVIEDKCDTCDGKGTNQVTKKLKITIPAGVDNGTRLRIKDEGDAGQRGGPPGDLYVYLFVNEDEEFQRDGINVISEIKVSYLQAILGCRLEVNTVDGPVELIIPAGTQPNTVMKLENRGVPRLGNPVSRGDHLLTVLIDIPTKVIPEERELLEKLAKIKGDRTGKGGLEGFLGNLFK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_SYNC1
Sequence: MDIRGTTIICVRHQGQVTMAGDGQVTLGNTVMKHGARKIRRMYEGRILAGFAGSTADAFTLFEKFEAKVQEFHGNLPKAAVALAKDWRTDQILRKLEALLIVADTNTTLVLSGAGDVIEPDDGIAAIGSGGSYALAAARALTRHAGLPSEQIATEALRIAGEICIYTNDHISSESLP
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_GEOSM
Sequence: MRKELLKKVKRVVVKIGSGVLTGENGGVDPGFLDGLAAQVAELSGQGTEVVIVSSGAVAAGRQALGLPDRPRTLPQKQAAAAVGQSRLMRAYEEAFSSYDLKVAQILLTRDDLANRRRFQNARGTLDTLLACGIIPVINENDTVVVDELKFGDNDNLSALVTNLVEAQLLLIMTDIDGLYTADPRTDPNATLIHQVGAVTRELERGAGGSGTSVGTGGMATKLAAAKKVVKSGVAAIIFAGRGERTLSRVMKGELLGTLFLPAGESLNRRKHWIAFTIKPAGSIVVDAGARDVLARHGRSLLPSGIAQVEGRFDRGACVRVLDPDGVEFARGITDYSSQEVEKIRGHQSSEIERILGFRYGDDVIHRDNLVLL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_SHESR
Sequence: MSKRDYYEVLGVGRDASEREIKKAYKRLAMKFHPDRNPGDKAAEASFKEVKEAYEILTDANKKAAYDQFGHAGVDPNRGGGGGYGGAGDFGDIFGDVFGDIFGGGRRGGQRQAARGSDLRYNLELSLEEAVKGLTKELRIPTLASCDVCDGSGAKKGTSATTCGTCHGQGQVQMRQGFFTVQQACPTCHGRGKIIKDPCTKCHGDGRVEKTKTLSVKIPAGVDTGDRIRLAGEGEAGEFGAPPGDLYVQVTVREHAIFVRDGNNLYCEVPISFSKAALGGEIEVPTLDGKVSLKIPAETQTGRMFRLRGKGVKSVRSHAVGDLLCKVVMETPVNLNERQKELLREFEATLTGESKKHSPKAEGFFDGVKKFFQDLNS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_ECO27
Sequence: MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIEFCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CAN1_CANAW
Sequence: MPEDYEKYRMGSSNESHQKLVQPISSSISKSNKKTKHQTDFVQDSDIIEASSINDEFGEVKRDLKARHVSMIAIGGTIGTGLFISTGSLLHTTGPVMSLISFLFVTTICFSVTQSLGEMATYIPISGSFAQFVTRWVSKSCGAANGWLYWFSWAVTFGLELSVVGQVIQFWTDAVPLAAWISIFFVILTIFNFFPVKFYGEVEFWIASIKIIAVFGWIIYAFIMVCGAGKTGPVGFRYWRNGYAWGDGILVNNNGKYVAAFVSGLINSIFTFQGTELVAVTAGEASPRALRSAIRKVMFRILVFYVLCMLFMGLLVPYNDPKLTQDGGFTRNSPFLIAMENSGTKVLPHIFNAVIVTTIISAGNSNIYSGSRILYGLAQAGVAPKFFLRTNKGGVPFFAVAFTAAFGALGYLACSSQGNKAFTWLLNITATAGLISWGFISVSHIRFMKTLQRRGISRDTLPFKAFFMPFSAYYGMVVCFIVVLIQGFTVFWDFNASDFFTAYISVILFVVLWVGFHFFFYGFGKDSFKMSNILVPLDECDIDSGVRDINDAEFDIPPPKNAWDKFWANVA
What is the function of this protein?
High-affinity permease for arginine and lysine.
What are the official names of this protein?
Lysine/arginine permease, Basic amino acids permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STT3_YEAST
Sequence: MGSDRSCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRATKYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPGYISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMVSAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPFVGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQISTAKFKVIMMVSLFLILVLGVVGLSALTYMGLIAPWTGRFYSLWDTNYAKIHIPIIASVSEHQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLTLTPVICVSAAVALSKIFDIYLDFKTSDRKYAIKPAALLAKLIVSGSFIFYLYLFVFHSTWVTRTAYSSPSVVLPSQTPDGKLALIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFGGLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETMRNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDEVFTSENWMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV
What is the function of this protein?
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (PubMed:12359722).  This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets (PubMed:29301962).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3, Oligosaccharyl transferase subunit STT3, Staurosporine and temperature sensitivity protein 3.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YGBE_ECOLI
Sequence: MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
What are the official names of this protein?
Inner membrane protein YgbE.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FUCM_HAES1
Sequence: MLKGIHPAISPDLLKILAEMGHGDELVLSDAHFPAHQLHHKVVRADGISINSLLTGIAPLFEFDTYTEAPLIMMQAVEGDSLDPAVEQSYLQTIKSAVGNVPKLARMDRFAFYERAKQAYAVVITGETAKYGNIIIKKGVTPVK
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_CITK8
Sequence: MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFMAIKLINKLNRKKEEPTEAPAPTTEEVLLSEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_STAAC
Sequence: MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LIAS2_PEA
Sequence: MMYSRFRTVAGNLNCAAKRLSSSSTTTTTTSAPSELQQNLAALRARLAMESPSLSDFISLKSDNAYSVEVGTKKKPLPKPKWMKESIPGGEKYVQIKKKLRELKLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPDEPTNVAEAIASWGLDYVVITSVDRDDLPDQGSGHFTETVQKLKALKPSMLIEALVPDFRGNAECVEKVSKSGLDVFAHNIETVEELQSAVRDHRANFKQSLDVLMMAKEYAPAGTLTKTSIMLGCGETPDQIVKTMEKVRAAGVDVMTFGQHMRPSKRHMPVSEYITPEAFEKYQTLGMEMGFRYVASGPMVRSSYKAGEFYIKSMIDSDRAASS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 2, mitochondrial, Lipoate synthase 2, LS 2, Lip-syn 2, Lipoic acid synthase 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FDB88_GIBM7
Sequence: MLLRLPPVFLTVLIAIASCSVYILNIAIESGFADSPYNFNQTTVGLAYMSTGIGYILSSMAGGRWMDSIMAREARKVVRSDSHGKLISLPEDHMKENAWVANTLYPLSSLWFGWTMYYGVQFMVPISALFVFGFTLMLHFTLGTTMLTEFVRKRSSAGVTVNNFVRNILSCVGTIVAAPWMKGVGLRYMMTKLCIICLLLGSLGIWLITRNAQRWRGTLDKALKEMD
What is the function of this protein?
MFS-type transporter; part of the Fusarium detoxification of benzoxazolinone cluster 1 (FDB1) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).
What are the official names of this protein?
MFS-type transporter FVEG_08288, Fusarium detoxification of benzoxazolinone cluster 1 protein FVEG_08288, FDB1 cluster protein FVEG_08288.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRCB1_BIFLO
Sequence: MMWMICLFGGLGAMARYVLDVSIQRGWNRENRRTNRNFPLSTLVINGVASLCAGIAMMSYYSQSVDMDTVMMFVVGFLGGFSTFSTALNEVVSLIRQRRFTLALGYGIATVAVPLICVAAGFGIALLANPA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSRA_LACP7
Sequence: MNKTIYIAAGCFWGGEKYFSLIHGVLSTKVGYANGTTSNPTYEEVCHNNTGHAETVEIQYDDSILPLEKLLRLYYEVIDPTSVNKQGGDQGIQYRTGIYYIDEADLEIIKPSLEELAKKYDKPIAIEVKQLLHFYDAEEYHQKYLDKNPSGYCHIGQCAFDSAKNA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: AKH_TYRGL
Sequence: QVNFSPGW
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_BURTA
Sequence: MARPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVEQIDYKDTETLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALLPYTDQHKA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MT1_CHLAE
Sequence: MDPNCSCATGVSCTCADSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCVCKGASEKCNCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1, MT-1, Metallothionein-I, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.