PharMolix/UniProtQA huggingface dataset:
Protein: HEM6_COXBR
Sequence: MRKDRQNKITEVGIYLKGLQNRLCRAFEKEEGESRFQETLWEKPNGGGGRTRLLTEGHVIEQGGVNFSCVYGNQLPPAATQKHPEISGFAFQAEGLSLVIHPRNPYVPTVHANFRFFIAGKDEADPRWWFGGGYDLTPYYGFEEDCRHWHRVAKKACDRFGEAIYPRFKAACDDYFYLKHRNEPRGIGGLFFDDLNEWEFKRCFEFIKILGDSFLEAYLPIMQNRKNHPYGERQREFQLYRRGRYVEFNLLYDRGTRFGLEFGGRTESILMSLPPRVVWRPNWEPEPGSEEARLYEDYLVRRNWVSVSGA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_YEAS7
Sequence: MVVGTKKYSNLDFVPTISDSEDDVPILDSSDDEKVEAKKTTKKRKGKNNKKKVSEGDNLDEDVHEDLDAGFKFDLDADDTTSNFQGWNFLAEGESNKDDAEAFVKKDVDLDKIIRRKGGLVKMAHIDSKQEEETEKEKVEKENDSDDEELAMDGFGMGAPMNNGDENQSEEEEEEEEEEEEEEEEEEEEQEEMTLEKGGKDDEIDEEDDSEEAKADFYAPETEGDEAKKQMYENFNSLSLSRPVLKGLASLGYVKPSPIQSATIPIALLGKDIIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVADVGKQIARFVSGITFGLAVGGLNLRQQEQMLKSRPDIVIATPGRFIDHIRNSASFNVDSVEILVMDEADRMLEEGFQDELNEIMGLLPSNRQNLLFSATMNSKIKSLVSLSLKKPVRIMIDPPKKAATKLTQEFVRIRKRDHLKPALLFNLIRKLDPTGQKRIVVFVARKETAHRLRIIMGLLGMSVGELHGSLTQEQRLDSVNKFKNLEVPVLICTDLASRGLDIPKIEVVINYDMPKSYEIYLHRVGRTARAGREGRSVTFVGESSQDRSIVRAAIKSVEENKSLTQGKALGRNVDWVQIEETNKLVESMNDTIEDILVEEKEEKEILRAEMQLRKGENMLKHKKEIQARPRRTWFQSESDKKNSKVLGALSRNKKVTNSKKRKREEAKADGNGARSYRKTKTDRIADQERTFKKQKSTNSNKKKGFKSRR
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1, Deficiency of ribosomal subunits protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PHLD_MYCBO
Sequence: MSQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC
What is the function of this protein?
Involved in virulence (By similarity).  Induces cytotoxic effects on mouse macrophage cell lines, via direct or indirect enzymatic hydrolysis of cell membrane phospholipids (By similarity).  Hydrolyzes phosphatidylcholine (By similarity).
What are the official names of this protein?
Phospholipase C D, PLC-D.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Remains associated with the cell.
Protein: LGT_STRSV
Sequence: MIDPVAIQLGPISIRWYAICIVTGLVLAVYLAMKEAPRRKIIPDDILDFILVAFPVAIVGARLYYVAFEWDYYGKNLIKIIDFWNGGIAGIAIYGGLIAGAIVLYFFCRRRLIHPVDFLDIAAPSVMIAQSIGRWGNFANHEAYGAAVKSLDYLPSFIRENMYIEGSYRQPTFLYESVWNLIGFILIIVLRRRPKLLRQGEIAAFYLIWYGFGRMIIEGMRTDSLMFAGLRVSQWLSLILIFVGIGIIIYQRKKKAPYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_BARHE
Sequence: MANTPSAQKAVRKVAARTQVNRARRSRVRTFMRKFDDALAGGDRASAEVAFKNFEPEIMRAVSKGVFHKNAAARKVSRLAKRLKALSV
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL2_STRA5
Sequence: MGIKVYKPTTNGRRNMTSLDFAEITTNTPEKSLLVSLKNKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKAYILAPKGLEVGQRIISGPEADIKVGNALPLANIPVGTVIHNIELQPGKGAELIRAAGASAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRNRWKGVRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FND10_HUMAN
Sequence: MRAPPLLLLLAACAPPPCAAAAPTPPGWEPTPDAPWCPYKVLPEGPEAGGGRLCFRSPARGFRCQAPGCVLHAPAGRSLRASVLRNRSVLLQWRLAPAAARRVRAFALNCSWRGAYTRFPCERVLLGASCRDYLLPDVHDSVLYRLCLQPLPLRAGPAAAAPETPEPAECVEFTAEPAGMQDIVVAMTAVGGSICVMLVVICLLVAYITENLMRPALARPGLRRHP
What are the official names of this protein?
Fibronectin type III domain-containing protein 10.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL25_SHEPC
Sequence: MSYTIQAQTRTEIGKGSSRRLRHAGKVPAVIYGQGKEPVSIVFEHKDIINIQANEDFYTSVVTIVLDGKEVGVRAQAMQRHVFKPIIEHVDFVYA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: DPPC_ECOLI
Sequence: MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
What is the function of this protein?
When a foreign outer membrane heme receptor is expressed in E. coli, DppABCDF can also transport heme and its precursor, 5-aminolevulinic acid (ALA), from the periplasm into the cytoplasm.
What are the official names of this protein?
Dipeptide transport system permease protein DppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL44B_YEAST
Sequence: MVNVPKTRKTYCKGKTCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L42-B, L41, Large ribosomal subunit protein eL42-B, Maintenance of killer protein 18, YL27, YP44.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_STRPS
Sequence: MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKQLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURF6_MOUSE
Sequence: MASLLAKDTYLQDLAKKICAQPGPERQRSTWGVRTKGSEAAGAPKKKRKKTQKKSPEQEQKAMDHKTKALGKKPPTSSRPKNPMVSKQEKGLSSLGSPKDSQGTARESVFALDFLRQRLHEKIQLARGQGSTKELSAATLEKRQRRKQERERKKRKRKERQAKQQVAEAEKKEEPVEVTPKMACKELQESGLIFNKVEVTEEEPASKAQRKKEKRQKVKGNLTPLTGRNYRQLLDRLQARQGRLDELRDQDAAKAQELEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKAHKKGRVLPQDLERAGLS
What is the function of this protein?
Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA.  May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly.
What are the official names of this protein?
Surfeit locus protein 6.
What is the protein family that this protein belongs to?
Belongs to the SURF6 family.
Protein: VUP2_ARATH
Sequence: MENSVNNCVRQRVFSNHQIRMIHEEEDHEESSWIVYFEDIDHDDEMVETEGEMTHYYDNDSSMISDAASPVHTTKINNVVRRKANNINTNPKKRRIIHQHKEEEEEELQKGEEEEEDEEDTASSPSNKTKIFSVLDHANDNTRYGKTMDNVTSEEIGCITETGSKIKEIMNEEFSAELKKRGLCVVPLSMLSNFIA
What is the function of this protein?
Involved in the regulation of plant growth.
What are the official names of this protein?
Vascular-related unknown protein 2.
Protein: LEXA_KORVE
Sequence: MVALTRRQREMYDFLCSFTDSHGYSPSFEEIAEGMGLSSLATVHKHIGNLESKGLLKRDYNRARSIEVLRPKGQLKKSMAAAAAVATAGLPFLGRIAAGQPIEAIENPETISLGDFTGSKEVFVLQVSGESMQDEHIVDGDYVLVERINTARDGEIVVALVENSDTTLKRIYREGETVRLQPSNAKMQPIRVPAGSVQVQGRVIGVLRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL20_GEOTN
Sequence: MPRVKGGPVTRRRRKKVLKLAKGYFGAKHALYRVANQQVMKSLMYAYRDRRQRKRDFRKLWIARINAAARQNGLSYSRLMHGLKLAGVEVNRKMLADLAVNDQAAFAQLADLAKANLNK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CLK3_MOUSE
Sequence: MPVLSARRKRLASTAGPRRGSGPSLAVRWVPPLGPEPSSDRGRAPMRPRGPTCSTTRRGAGRGPRLLPGPPGRDLHRCRPDPGGAGQSPRVCEFGARAVRPLGRVEPGPPTAASREGAVLPRAEARAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRIPYQRRYREHRDSDTYRCEERSPSFGEDCYGSSRSRHRRRSRERAPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSRNPSR
What is the function of this protein?
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates.  Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex.  May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution.  Phosphorylates SRSF1 and SRSF3.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
What are the official names of this protein?
Dual specificity protein kinase CLK3, CDC-like kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: ZMYM1_HUMAN
Sequence: MKEPLLGGECDKAVASQLGLLDEIKTEPDNAQEYCHRQQSRTQENELKINAVFSESASQLTAGIQLSLASSGVNKMLPSVSTTAIQVSCAGCKKILQKGQTAYQRKGSAQLFCSIPCITEYISSASSPVPSKRTCSNCSKDILNPKDVISVQLEDTTSCKTFCSLSCLSSYEEKRKPFVTICTNSILTKCSMCQKTAIIQYEVKYQNVKHNLCSNACLSKFHSANNFIMNCCENCGTYCYTSSSLSHILQMEGQSHYFNSSKSITAYKQKPAKPLISVPCKPLKPSDEMIETTSDLGKTELFCSINCFSAYSKAKMESSSVSVVSVVHDTSTELLSPKKDTTPVISNIVSLADTDVALPIMNTDVLQDTVSSVTATADVIVDLSKSSPSEPSNAVASSSTEQPSVSPSSSVFSQHAIGSSTEVQKDNMKSMKISDELCHPKCTSKVQKVKGKSRSIKKSCCADFECLENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQFCDGAVSDDLSIHSKQIEGNKKYLKLIIENILFLGKQCLPLRGNDQSVSSVNKGNFLELLEMRAKDKGEETFRLMNSQVDFYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAFSIICDETINSAMKEQLSICVRYPQKSSKAILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSIIRFCKEVKELRSALKTLSSLFNTICMSGEMLANFRNIYRLSQNKTCKKHISQSCWTVHDRTLLSVIDSLPEIIETLEVIASHSSNTSFADELSHLLTLVSKFEFVFCLKFLYRVLSVTGILSKELQNKTIDIFSLSSKIEAILECLSSERNDVYFKTIWDGTEEICQKITCKGFKVEKPSLQKRRKIQKSVDLGNSDNMFFPTSTEEQYKINIYYQGLDTILQNLKLCFSEFDYCKIKQISELLFKWNEPLNETTAKHVQEFYKLDEDIIPELRFYRHYAKLNFVIDDSCINFVSLGCLFIQHGLHSNIPCLSKLLYIALSWPITSASTENSFSTLPRLKTYLCNTMGQEKLTGPALMAVEQELVNKLMEPERLNEIVEKFISQMKEI
What are the official names of this protein?
Zinc finger MYM-type protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CF100_HUMAN
Sequence: MLQVVQEGNPAPFIINTVKRGRRDRERQRTPWAPHPLGFQGRRYIYESPNHRGKDSSFLAQK
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01556.
Protein: O16A_CONEB
Sequence: LNKRCAGIGSFCGLPGLVDCCSGRCFIVCLP
What is the function of this protein?
This toxin activates voltage-gated sodium channels.  It shifts the voltage-dependence of activation to more hyperpolarized potentials but has only little effect on channel inactivation.  It is active on Nav1. 3/SCN3A (EC(50)=3. 98 nM), Nav1. 4/SCN4A (EC(50)=4. 99 nM), Nav1. 6/SCN8A (EC(50)=1. 27 nM) and Nav1. 7/SCN9A (EC(50)=2. 42 nM) voltage-gated sodium channels.  In vivo, it induces nocifensive or pain-like behaviors in mice when injected intraplantarly.
What are the official names of this protein?
Delta-conotoxin-like ErVIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_KOSOT
Sequence: MRRRRAVKREVAPDPIYNDVLVTKLINRVMKDGKKSKAEKIVYKALEMLSEKTKQPPMEAFKKAINNVKPLLEVRPRRVGGATYQIPFEVPEDRALSLALRWIVAAARAKSGRPTSERLALELIDAYNGTGVAVKKREDVHRMAEAGKAYAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: AMPA_CENSY
Sequence: MKITADASDPAKRKTAALCGFVLEGAAGAAGLGGPGLDDLIKEAIGKNGGKKGRISMTGTPGMPSERVILAGLGPAGKVTSDGIRSEAGRLARQVRDMGLADFAVAAPSILDPAEEAALIVEGAELALYSFDEFKAEKAGNSPRLHILGGGPSAARAIKDAQSITAGVAFARGLANMPPNECPPDKLGRAAVKMCTGKKMRCIVLKKPELKKGGFGGIIAVGQGSSNEPRLIIVEYNGGKKGQKPIVLVGKAVTFDTGGISIKPGEKMDEMKFDKCGGCTVLGIMKAVEDLALPVNVIGIVPSVENMPGGSSYRPGDIVKLYSGKTAEILNTDAEGRLILADALSYGEKKYAPSEIIDFATLTGACIVALGNNVAGMVSNDDAFAKRIEGASERTAEEVWRLPINDDYMSMIKSEVADMRNLGMGRAAGTITAAAFLKNAIGDTPWVHLDIAGTAWNQPATKKKPYNPGGATGFGVRLVAGYLKGRAQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_METRJ
Sequence: MDIRAAEISAILKDQIKNFGEEAEVSEVGQVLSVGDGIARAYGLDNVQAGEMVEFESGVRGMALNLEQDNVGIVIFGSDREIKEGQTVKRTGAIVDVPVGKGLLGRVVDALGNPIDGKGPIQSTERRRVDVKAPGIIPRKSVHEPMATGLKAIDALIPVGRGQRELIIGDRQTGKTAIALDTILNQKPGHTAGGDEKAKLYCIYVAIGQKRSTVAQFVKVLEDQGALEYSIVIAATASDAAPMQFIAPFAGCAMGEYFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMGDAAGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFYQGVRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQALLNRGSRLTELLKQPQFSPLKMEEQVAVIYAGVNGYLDKLPVTKVRAFEDSLLSTLRSKHKDLLDSIAASKDLSDENAGKLKSVVESVAKSIG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYK_NITEU
Sequence: MTQEEISGISQDENNLIAERRSKLTALRQTGNAFPNDYRRDNLARILHEKYDSCSREELESSQVTVKVAGRMLFKRVMGKASFATIQDMSGRIQLYISNDHTGETAHEAFRHYDLGDILGAEGVLFKTRTDELSLRVTQLHLLTKSLRPLPEKFHGLADQEQKYRRRYLDLITNEDTRRVFAIRSKIIQAIREFLVDRDYLEVETPMMHSIPGGATARPFVTHHNALDMSLYLRIAPELYLKRLVVGGMEKVFEINRNFRNEGISTRHNPEFTMLEFYEAYQDHNYLMDLTESMLREVALKVSGTTRIVYQQREMDLAQPFARLTIAQAILKYHPEYSDAQLNDRDFLTKALQAKGVTVNPDSGIGGLQLALFDETTEHLLFEPVFIVDYPAEVSPLARCNDANPEITDRFELYIAGREIANGFSELNDPEDQANRFLEQARAKEAGDLEAMHYDADYIQALEYGLPPTAGEGIGIDRLVMLLTDSPSIRDVILFPQLRKED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX3Y_PANTR
Sequence: MSHVVVKNDPELDQQLANLDLNSEKQSGGASRASKGRYIPPHLRNREASKGFHDKDSSGWSCSKDKDAYNSFGSRDSRGKPGYFSERGSGSRGRFDDRGRSDYDGIGNRDRPGFGRFERNGHSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFGDIDMGEIIMGNIQLTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGAAGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNINITKDLLDLLVEAKQEVPSWLENMAYEHQYKGGSRGRSKSNRFSGGFGARDYRQSSGSSSSGFGASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
What is the function of this protein?
Probable ATP-dependent RNA helicase.  May play a role in spermatogenesis (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX3Y, DEAD box protein 3, Y-chromosomal.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm in an XPO1- dependent manner.
Protein: RPOC_ALKMQ
Sequence: MYELNNFRSIKIALASPEKIRQWSKGEVKKPETINYRTLKPEKEGLFCEKIFGPTRDWECHCGKYKRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRSLEKVLYFAAYIVINPGETPLTEKQILTEKEYADAIEKYGPKFKAGMGAEAVKGLLESIDLDAMNIELRHKLKESTGQKRIRTVRRLEVVEAFRKSKNNPAWMILDVVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGKPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKFYQCGLPKQMALELFKPFVMKKLVQENYAHNIKSAKRMVEKVKPEVWGVLEEVISQHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADFDGDQMAVHVPLSVEAQAESRFLMLSINNILAPKDGEPITTPTQDMVLGCYYLTIQDEGVLGEGTIFKDFEELLLAYETKAVSLHAKVKVRMKLSAEDSGKLVESTVGRFIFNEKIPQDLGFVDRSKDLYALEVDFLCTKGALGKVIGKCFRKHGNTITSIMLDYIKELGFKYSTRGAITVAVSDMDVPEAKAELISQAEQRVDKYEKAFRRGLISDEERYEKVIETWTETTEKVTDALMAGLDRFNNIFIMADSGARGSKNQIRQLGGMRGLMANASGHTVEIPIKSNFREGLTVLEYFTSTHGARKGLADTALRTADSGYLTRRLVDVSQDVIIRELDCGTETGIVAKAFKDGNEVIEELYFRIVGRHSIDDIIHPETKKVIVPKGDIIFEDAAETITEAGIEKVAIRSALACRSKHGVCGTCYGRNLATGEPVKVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRVEELFEARKPKGLAIISEISGKVDISESKRKREVTVTDENQEVVTYTIPYGSRVKVKQGQILEPGDEITEGSVNPHDILRIKGVEGVQTYIIKEVQRVYRLQGVDINDKHIEVISRQMLSRIKVEEAGDTELLPGSLENVFAFELANQKAIEEGGEPATGNIALLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVIIGKLIPAGTGMKRYKNIAISTETDEKLDEIEETL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MTUS1_MOUSE
Sequence: MNDDNSDRTEDGSRYVFIRDKNSNPSEYYQTSLSAQCPSVSHGDWNSDNPDAMVVDYEMDPAVDSSESVSLSHQCVEELAYPEPSSDFMGKHEFTMYSELTCQSPALVNTGKPQDLHSNCDSLEAIQDEKFDPLKPCECRSDDDYACGDSPEVLELKQTYGMKVDTANYTFIARHDIEQGQPLHAPGGLQTTVRDRNALSSCGRTPPHSSKMYVRGVNYNRENFENLQATPSKTLNTTFTVISDVLMQTDSPDVGVQGQNSLGNVTKEYTDGTRRGLIGEKEIQAVTLVSDGMEVPNGSASQEFYCVSEDDPNSETHSHGPYAQQEMGQNLRGTLPNCHVDGECPVLVPAFEKSKTRVLGSECKVTVTEDPHIDSHDNDSDIQSSTEELTLRSVSGQRGSPYEMGWGENGGAICTDKAGCMSTPVEQPPNLSFRLEPAEVKKYNNVENGPRDAKRAPNLKGEPTNMPKPNLGKSATKTNTTVGSKVRKTEIISYPTPNFKNIKAKVISRSVLQPKDTSIMKDTPSPQVTGGSSPSPGPSKHLTMMNKAPRSDFKASKKAEIPINKTHKQQFNKLITSQAAQVTTHSKNASLGVPRTTSATKSNQENVDKTGSPHAGSETGSVAAFFQKIKGILPVKMKSSECLEVTYVSHIDQISPEKGEQDGEAPMEKQELGKQATNEIFESKSLLVGSAPKTSTTPGRSSSKPDSRSLRKTPGLKAKVGPTAACLRRKSESRTLGSDRALSPQRIRRVSGSGGHAAINKYEEKPPKQAFQNGSGPLYLKPLVPRAHSHLLKTSPKGPSRKSLFTAFNSVEKGRQKNPRSLCIQTQTAPDVLSSERTLELAQYKTKCESQSGFILHLRQLLSRGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVSLRGELVAASSACEKLEKARADLQTAYQEFVQKLNQQHQTDRTELENRLKDLYTAECEKLQSIYIEEAEKYKTQLQEQFDNLNAAHETTKLEIEASHSEKVELLKKTYETSLSEIKKSHEMEKKSLEDLLNEKQESLEKQINDLKSENDALNERLKSEEQKQLSREKANSKNPQVMYLEQELESLKAVLEIKNEKLHQQDMKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAALQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPFQSPRNSGSFSSPSISPR
What is the function of this protein?
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation.  May be required for AGTR2 cell surface expression.  Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation.
What are the official names of this protein?
Microtubule-associated tumor suppressor 1 homolog, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Coiled-coiled tumor suppressor gene 1 protein, Mitochondrial tumor suppressor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MTUS1 family.
What are the subcellular locations of this protein?
Mitochondrion. Golgi apparatus. Cell membrane. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
Protein: SECG_RICTY
Sequence: MLDILLFVHITISILLIIVILMQRSGSGGISGISGDNNMGVVSAKTVGNFLSKSTIILTTLFLINAIILANLSSKKKSNLVSKINEIEENQTDNSLPIAK
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation (By similarity).
What are the official names of this protein?
Protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.