PharMolix/UniProtQA huggingface dataset:
Protein: MTH_DROSI
Sequence: MKTLFVLRISTVILVVLVIQKSYADILECDYFDTVDISAAQKLQNGSYLFEGLLVPAILTGEYDFRILPDDSKQKVASHIRGCVCKLKPCVRFCCPHDHIMDNGVCNDNMSEEELTELDPFLNVTLDDGSVSRRHFKNELIVQWDLPMPCDGMFYLDNREEQDQYTLFENGTFFRHFDRVTLSKREYCLQHLTFADGNATSIRIAPHNCLIVPSITGQTVVMITSLICMVLTIAVYLFVKKLQNLHGKCFICYMVCLFMGYLFLLFDLWQISISFCKPAGVLGYFFVMAAFLWLSVISLHLWNTFRGSSHKASRFFSEHRFLAYNTYAWGMSMVLTGITVLADNVVEDQDWNPRVGEEGHCWIYTQAWSAMLYFYGPMVFLIAFNITMFILTARRIIGVKKDIQNFAHRQERKQKLNSDKQTYTFFLRLFIIMGLSWSLEIGSYISQSNQTWANVFLVADYLNWSQGIIIFILFILKRSTLRLLQESIRGEGEEVDNSEEEISLENTRFDRNVLS
What is the function of this protein?
Involved in biological aging and stress response.  Essential for adult survival (By similarity).
What are the official names of this protein?
G-protein coupled receptor Mth, Protein methuselah.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDRP_I07A0
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGRWTKNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCIETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLIANESGRLIDFLKDVMESMDRDEVEVTTHFQRKRRVRDNVTKKMVTQRTIGKKKHKLDKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNDSTKKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNYAGIQAGVDRFYRTCKLLGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGVNESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWDQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVIMPAHGPAKNMEYDAVATTHSWVPKRNRSILNTSQRGVLEDEQMYQRCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEDLRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: SLX4_ASPFU
Sequence: MCTTTDVVVLSSSPDQIRSCSLANPKCGAEKAFVLSPVSSSPSFLPSSSDLFQPPTRSRFFKPGGGNEGSSRTAREESETGTKQNDLAASRKKAAVRGGRQKRTKEQPPNESQTLFDNPEPPIPKHNGCTSKKGTGSRKKRIDAASKCTKSGSKKITGKVTKPGITETTKFENKTKNVTSDVSPGKSPANKLELEKDGLQIEVAMKRRLDWTPTKDTGKQAVALDDTGDNKTRFGELLSEYGFLKAAAVSQTDSKLSDGAPTKCRRLELVDTHNPSTSKRTSPDADSDRSNVRSTRSSRAPAAEGKSKKRSRKITTLTGRVTALYTKDCTDHLDAANTMIRASEDVSSKLLSKSLDLDSCVLAPGDAVDYLQDQDLIFGTCSQLEREDSPTMLRDMQKEICASKNSMIENRKPSSTTRAGSGLYSHTTVSRFQTQRDLWSVAARDMDGSLAEIEVLDMVDITDVSELPPKPNGELPDRSEKNDEDTVSQGESSRPIEITDDFGVEVDVRMEYLATSETKPEETAYAASEIRPMPRFADWKDSDLSRQVRLYGFKPMKNRRKMIEVLERCWKAQHSSTRTGVQYAPGKPDDGSTGKAGTIGSQMNKQSSKMDAAEKMRRESACLKEKAKSSTALEDKLSHATDRSSQMLTKSSFAHMEEIEDSEDEVIPSPSQLQSLYKRHISESRSSHPLPVSDTPSTPSSRTRTNADSDTKPSPSDSATESSLPDLASQITKAVRLQPRSFSVDCKRPSWHEKILMYDPIILEDFATWLNIEGLGLVHEDREVSAEFVRQWCESNGICCGFRKNSRRSER
What is the function of this protein?
Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y760_BACCZ
Sequence: MNIWLSMLTTTGLGAIIGGFTNHLAIKMLFRPHRPMYIGKFQVPFTPGLIPKRRDELAVQLGKMVVEHLLTPEGIGKKLTNEEFQKGLIHWAQVEVDKVITNEQSLRHMLGKWDVAHVEKEATEKIEQVITEKIQAFLEEYYTYTWEQALPHSVHEKIENAIPNVSAFILKRAIHFFESEEGKSRLSKMIDDFFASRGALLNLVGMFLGNVSVVDRVQPEVIKFLGQDGTKQLLTDVLQKEWEKLKGRDVKELETFVEKEMIVSSILSAVKVEETVSKFLNQSVKQVCEPVRETIIEKVVPKAVTKGLKWGGENVESILNNLHLAEIVQQEVSTFSTERLEDLVLSITKNELKMITYLGALLGGMIGIVQGLLLLFLK
What are the official names of this protein?
UPF0754 membrane protein BCE33L0760.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUM21_ARATH
Sequence: MADDNGKNPMPNDRGYDTLLTAFNNLKLYANYNHQEPGESGNTNINSNNNHPNPPLLTAFKSLKLYANKNNQEPGESGNTTINRNKNHPNPPLVTAFNNLELYANYNHQEPGESGTTNINNNNPNPPLLTAFDNLRLYANYNHQEPGESSNNNYPNLNVYNVGHISAASFNAPPFTPSSLTQPDDSSSRYSGKPFPPPPLSFVSPGVDKDRNWLSSLLDMMTCAQRFTEFQKYLQDLDTYPTAERESHLFKIGSALTTTKRIFLHLATNQYGSQALRILFRRSPSLDHLLFCAVDTNFFLLMSDKYGRGLIIPAIRAVDKTKKESLYKLTYEYTLHLARLETGCLALNNVLQEIRGIYRDLIFECVANNADWLSFDPYGTHVVQNILILQNPVATTAIAERLRGSFFRLAMERQGSYVVEKCLKSDFARDQVLEEFRGNAKEWVRMTTDKFGNFVVQSALRVMKEKEMRPLLREFVEKLRPHFGKMEIGRGRNTLRVIQEEIVGWINQLPDKSGYVN
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Putative pumilio homolog 21, APUM-21, AtPUM21.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L5_FOWPN
Sequence: MDRNINFSPVFIEPRFKHEFLLSPQRYFYILVFEVIVALIILNFFFKEEILYTFFPLAKPSKNSINSLLDRTMLKCEEDGSLMISRPSGIYSALSLDGSPVRISDCSLLLSSINGASSSTSPYSIFNRR
What is the function of this protein?
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.  Also plays a role in cell-cell fusion (syncytium formation) (By similarity).
What are the official names of this protein?
L5 homolog, Protein FPV132.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae L5 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein. Note=Component of the mature virion (MV) membrane (By similarity). The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis.
Protein: GLPK_ALISL
Sequence: MTEQKYIVALDQGTTSSRAVILDHDANIVSVSQREFTQIYPQAGWVEHDPLEIYATQSSTLVETLAKAGIRSDQIAAIGITNQRETTIVWNKETGKPVYNAIVWQCRRTADTCEKLKEAGLEEYIRENTGLVVDPYFSGTKIKWILDNVEGAREDAEAGKLLFGTVDTWLVWKMTQGRVHVTDYTNASRTMVFNINTLQWDEKLLKELDIPLSMMPEVKSSSEVYGETNIGGKGGTRIPIAGIAGDQQAALYGQMCVEQGQAKNTYGTGCFLLMNTGKEKVTSRNGLLTTLACGPRGEASYALEGAVFMGGASIQWLRDEMKLLADAKDSEYFATKVDSSNGVYVVPAFTGLGAPYWDAYARGTIVGLTRGCGSNHIIRATLESIAYQTRDVIDAMQADSGIKLSALRVDGGAVANNFLMQFQADVLDVAVHRPQVTEVTALGAAYLAGLAVGFWGGLDELAGKAVIDRSFEPHHDEIKRNQRYRGWKRAVKCAQSWAELHDEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: YC09_KLEPN
Sequence: MAKIIVVSTDCPYPANHGGRLDILMRLELLSSTGHDVDLIVTYKEEIDEASKQYLERICKNVYYAQRLGMIRSAFNDMLKFLPLQVKSRSRLREIKLNKKYDYVLCESEYVYSILKNSTLDAKNKLLRVHNDEVVYYKALFNDENSIFKKIYYFYEMLAFKYNKKDINSSFDKLLFISKDECDKESKGIWLPSHIPVMHPFKYDKFDLHNCNVLFVGNLFMPNNLQGLIWYLNKVHPMVIKENPDIKLTIAGNAKNGISEELKKAISIYDGNAINLITSPSDEELQAIYDGNCIFINPMLNGAGVKLKNLDAMRNTMFVVSTSIGSEGTGTNHGEQLVIANDEVLFAKHIINYSKNISGMKEIAFNAFSFIQENYDSKKVFSSIFKEN
What are the official names of this protein?
Uncharacterized 44.6 kDa protein in cps region, ORF9.
Protein: RS182_CUPPJ
Sequence: MAFIKRSDKKKKPFKKESSLFKRKRYCRFTVAGVEQIDYKDLDTLKDFIGDNGKITPARLTGTKAHYQRQLNTAIKRARFLALLPYTDLHKH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RUVC_ACIB5
Sequence: MPLIIGIDPGSRLTGYGIIEKDGSKLRFVDAGTIRTETQEMPERLKRIFAGVERIVKFHGPTEAAVEQVFMAQNPDSALKLGQARGAAIAALVNLDLQVAEYTARQIKQSVVGYGAADKEQVQMMVMRLLNLTIKPQADAADALAAAICHAHASGSMSKLTVLNALGGMARGRSRSSSRRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ACEA_CANGA
Sequence: MPVPNSEANEFQALQARIDADAKEIEQWWSEPRWNKTKRTYSAREIAIRRGTFPPLTYPSSVMAKKVYKVLEKHHKEGTVSRTFGALDPVQVSQMAKFLDTIYVSGWQCSSTASTSNEPGPDLADYPMDTVPNKVEHLFKAQQFHDRKQWENRAKATSQEELDAMGPAIDYMTPIIADADAGHGGLTAVFKLTKMFIERGAAGIHMEDQTSTNKKCGHMAGRCVIPVQEHINRLVTIRMCADIMHSELVIVARTDSEAATLISSTIDTRDHYFVVGATNPDIEPFAEYMDRAIMAGVSGDELQKLEAAWIEKAGLKLFHEAFADEVNKSSVSNKQEIIKKFNDKVGPLTETSHREAKKLAKELLGKDIFFDWDLPRVREGLYRYRGGTQCSVMRARAFAPYADLVWMESNYPDFEQAREFAEGVKAKYPDQWLAYNLSPSFNWPKAMSVDEQATFIERLGQLGYIWQFITLAGLHTTALAIHKFSEDFAREGMKAYAQNVQQIEMDEGVDVLKHQKWSGAEYIDGLLKLAQGGVSATAAMGQGVTEDQFKSNL
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: DTDA_METM7
Sequence: MDYLFISSKTDPASQNIKKHVQNYGYNVFELEKKSTQSNFSDFPDSEMYIFLSKHASESKKPTLTVHTPGNLTEDNSHGGNPEEISPCNPVFNTLMLQNINKYNEMEEYKELGFEVSFEVLHHGPTDLKTPSAFVEIGSSEEQWQIDDAAEIITNSLIDTLNSIQNSEYEEKEKIIGIGGGHYSPKFTKLALREEYYVGYLTPKHAKLSENILNQLISKQEFDFVGIDWKGLYGEDKRKYVEFFDENDISWQRV
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: CYB_LEPAM
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNFLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDVLGFLMLILLPLLLLLFSPDFLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPFLHMSKQRSMMFRPISQVLFWILVADLLTLTWIGGQPVEHPFITIGQVASILYFSIILILMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_STRPZ
Sequence: MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREGFVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLGIAIISTSEGLLTDKEARQKNVGGEVVAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: VPP3_HUMAN
Sequence: MGSMFRSEEVALVQLFLPTAAAYTCVSRLGELGLVEFRDLNASVSAFQRRFVVDVRRCEELEKTFTFLQEEVRRAGLVLPPPKGRLPAPPPRDLLRIQEETERLAQELRDVRGNQQALRAQLHQLQLHAAVLRQGHEPQLAAAHTDGASERTPLLQAPGGPHQDLRVNFVAGAVEPHKAPALERLLWRACRGFLIASFRELEQPLEHPVTGEPATWMTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIYTGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGIDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTFLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATLVVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFAATDD
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Seems to be directly involved in T-cell activation (PubMed:10329006).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 3, V-ATPase 116 kDa subunit a 3, Osteoclastic proton pump 116 kDa subunit, OC-116 kDa, OC116, T-cell immune regulator 1, T-cell immune response cDNA7 protein, TIRC7, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLGC_ECO8A
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: DHYS_TOBAC
Sequence: MGEALNVMESVRSIVFKESENLEGSATKIEGYDFNKGVNYAELFKSMASTGFQAANLGDAIQIVNQMLDWRLSHEQPMEDCSEEERDVAYRESVTCKIFLGFTSNLVSSGVRDTIRYLVQHRMVDVVVTTAGGIEEDLIKCLAPTYKGDFSLPGAVLRSKGLNRIGNLLVPNDNYCKFENWIIPIFDQMYEEQIKEKVLWTPSKVIARLAKEINDETSYLYWAYKNRIPVFCPGLTDGSLGDMLYFHSFKKGDPDNPDLNPGLIIDIVGDIRAMNSEAVHAGSRKTGMIILGGGLPKHHVCNANMMRNGADFAVYINTAQEFDGSDSGARPDEAVSWGKIRGGAKTVKVHCDATIAFPILVAETFAAKRKELSHIRCQV
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.  Also able to produce homospermidine from putrescine.
What are the official names of this protein?
Deoxyhypusine synthase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: GRPE_MYXXD
Sequence: MTVIEVEASGPSTPVEAEASASPADTTSPPSDAEATPSEDVAALRQEVESLKAQLEFSQAKGRETMERLREAHERAKEAQERTVRHAADLENYRKRAQKEKEEVQRFGSEKLLKDLLPVMDNLDRAIDAAAKSPDLDSFEKGVAMTRKSFEDALGRHGVKGFSAKGQVFDPRVHEAIQQVETADVPAGHVAYEVVRGFYLNERLVRPAMVVVARAPAEPVAAAEPPAVAEPATATTDTEAPAAPAQSENSSGGSQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_AZOC5
Sequence: MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEVASEKA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs (By similarity).  Seems to be involved in the regulation of NifA.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PRFB1_ARATH
Sequence: MSMELTVLGPLAGRSFAIAGKPKLLLLRPTNLPLLRLSLPLSLPNFSSSSRFNSPIVFAAQESNLSVSNENETSEWLMQDFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDSTDVSLLEEAMGIIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEWGQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYLKHKYTLAMASAVTN
What is the function of this protein?
Directs the termination of translation in response to the peptide chain termination codon UGA.  Required for the proper translation, stability and normal processing of UGA-containing polycistronic transcripts in chloroplasts.
What are the official names of this protein?
Peptide chain release factor PrfB1, chloroplastic, AtPrfB1, AtPrfB, Protein HIGH CHLOROPHYLL FLUORESCENCE 109.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CH10_LEPBA
Sequence: MASIKPLGDRVVVEPKNESEEKIGSIIVPDTAKEKPQEGKVIAAGQGRYEDGKLVPLEVKVGDTVLYGKYSGTEIKQGGKDLLIIRESDILGVVTN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX1_NOSS1
Sequence: MLVLKTTDKEFSPRFQSLVSDRREATVDVSGTVRDILAHVKARGDAAVQEYTSRFDHYRPHSHHLSAAFIAEQAAKCSDEVKAALELAAERISSFHQKQLPQDIGYTDTAGVKLGLNWVALSQVGIYVPGGRASYPSSVLMNALPAKIAGVERIVMTVPMPHGEINPAVLAAAQVAGVTEIYSIGGAQAVGALAYGTETITPVDKIVGPGNAYVAEAKRQVFGTVGIDSIAGPSEILVVADRQNNPEWIAWDLLSQAEHDPSAQSILITDSESFAQQVIAAVEQILTTLPSQKVASSSWQNHGAVIIVRDLAESIPLLNQLAPEHVELCVDNPQLLASQIKCAGSLFLGRYTPEAIGDYLGGPNHVLPTSRSARFASGLSVYDFLKRITYLECNQAALQKIGQSAVTLAETEGLPAHAGSVAVRLQGLKDM
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase 1, HDH 1.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: O10J1_HUMAN
Sequence: MLLCFRFGNQSMKRENFTLITDFVFQGFSSFHEQQITLFGVFLALYILTLAGNIIIVTIIRMDLHLHTPMYFFLSMLSTSETVYTLVILPRMLSSLVGMSQPISLAGCATQMFFFVTFGITNCFLLTAMGYDRYVAICNPLRYMVIMNKRLRIQLVLGACSIGLIVAITQVTSVFRLPFCARKVPHFFCDIRPVMKLSCIDTTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVEGRKKAFATCASHLTVVIVHYSCASIAYLKPKSENTREHDQLISVTYTVITPLLNPVVYTLRNKEVKDALCRAVGGKFS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10J1, Olfactory receptor OR1-26, Olfactory receptor-like protein HGMP07J.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOAA_SYNP6
Sequence: MIVLADHHDRQFRYLRLSLTDVCNFRCGYCLPKGQQLDPQRPALLTLPEIRHLIEGFVALGIEKVRLTGGEPTLRSDLVDIVRAVAAVPGIRRVALTSNGWNLRDRLADLQAAGLTQLNLSLDSLDAARFQAITGSSRFEAVMAALEQAIALRLPILKVNAVLLKTLNYPQLSDFVEFVRDRPISIRFIELMQTLDNHDYFQQEFLSGSVLTEQWLAQGWQPIKRDRTAGPAQEYCHPNYQGKLGIIAPYSPNFCQNCNRLRVTSRGALRLCLFGTGEFDLRPWLQHPDQRSQLLEQVQQTLNFKTAGHQLAEANSGDTRNLATYGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.