PharMolix/UniProtQA huggingface dataset:
Protein: Y2775_MYCTU
Sequence: MKPSNIRIRAAKPIDFPKVAAMHYPVWRQSWTGILDPYLLDMIGSPKLWVEESYPQSLKRGGWSMWIAESGGQPIGMTMFGPDIAHPDRIQIDALYVAENSQRHGIGGRLLNRALHSHPSADMILWCAEKNSKARGFYEKKDFHIDGRTFTWKPLSGVNVPHVGYRLYRSAPPG
What are the official names of this protein?
Probable N-acetyltransferase Rv2775.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: KXCB_DICDI
Sequence: MELSEPKQRFESLLSLFEDVANKRYSGDFSVKKNINAPQVPPRSYSLFNVTGGNVSSYNNQQQQQNNNNNNNNNNNNNNNNNNNNNNNNNNSGEISSNNSTPSILFSPTPTSTAPPAPPQPTTPPNTGFHNRPLSININQQPIGGVNNNNNNNNKDSPSNKPLRLSGSPPTASINGNQIEQLQRELRNEKEAHQQTKYLLNSFADENKKLSNDCQLWRAKYFKLLTKNTKLKVIFDHFQSIMNESDSVPGEGSLVHSTSYNSSSSSSSGGGGNITPRKLSLAGGGKFDDAPQSASALLKIHHQRNQSTGSAFSNTIYNGEEKTRDTISYNERPKRQTVGSSTFFPPPPSRATSTSSIQVNSDPQEIEQLTEEQYLEMLEKRRQVSLQILQTEKEYAFYLNIIVEEFLQPLKNESNLSNNPFISKAQVKQLFGDTEVILGSSKLLAEDLENVLLDGTSNPIGLGDCFLKICDYFKLYASYVKNYYTSISVLNKLKEESHKFQAFIQEKEQILLDSNFTDLGALLVLPVSRIGQYTSMINYLFSLTPQSHPDYEPFKKAVIKMKSTVDYVKEKIRDNDSQNKVRIIQNQMTGKFENLNLPHRRYVREGMLTESGKGSNSNQYYCFLFNDIFVLSTPIKKSNQFSFKKKISLSEAEVTMISDPEDRPIFQISIQNIDSQQDNSPNMLSLNGIQNAINNMTNNDSKSKNNNNNNSNGNNNNNNINSNSNSNNNSVIDIKSSGVLINNGGGSGFISNNNGITNVNSNNNNNNNINSNNNINGNNNNGNNSVNYSNGEDNNDRECFTFIADSNRDREDWIQAIHANIISSKKRNETRKPEDIEKGGIDFSVSDIKLCEQIGSGGSGCTVHRCTVDGFTCAVKVLKLKNTSPFLVEQFISEITIMVKLSHQNIAKYLGHRLSGNQLWLFMEFYPHSLKDVITKRTSPFPATEVIWMALEIAKGLEFLHTQKNPIIHRDLKPGNIMCSLDDKGRVCSIRVCDFDTSKELGNGVTLKTCIGTPCYMAAEVLNVADGGNSGYSLKADIWSFAMLCFEIISLLPPYHQFQHLQSIEMIINGTCPPLPTDLIQPKLLQPLIELLVTCIDLNPNHRPNASQLVQKLTKMLKNTGMMTE
What are the official names of this protein?
Kinase and exchange factor for Rac B, Serine/threonine-protein kinase kxcB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
Protein: ORGRE_CUCME
Sequence: MDRVLVASYPINHLIRPHSFRIDYCWSTCFTSRLNSGKERQKLSSRWRWRSMASDSTDSSSSSSFAPSVESDPSDKTSASFCIIEGPETVQDFAKMELQEIQENIRSRRNKIFLHMEEVRRLRIQQRIKNAELGISKEERENELPNFPSFIPFLPPLSSENLKLYYVTCYSLIAGIILFGGLLAPTLELKLGLGGTSYEDFIRSVHLPMQLSQVDPIVASFSGGAVGVISALMVVEVNNVKQQEHKRCKYCLGTGYLACARCSNTGALVLIEPVSTLNGEHQPLSLPKTERCQNCSGSGKVMCPTCLCTGMAMASEHDPRIDPFD
What is the function of this protein?
Involved in chloroplast differentiation in fruit flesh.
What are the official names of this protein?
Protein ORANGE-GREEN, chloroplastic, CmOr-green, DnaJ-like cysteine-rich domain-containing protein Or.
What is the protein family that this protein belongs to?
Belongs to the orange-like family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane.
Protein: IF2_ACTPJ
Sequence: MSDNEIKNEAPKKLSLQRRTKTTVADGKVQVEVRKSRKIDTAAVKKAQEEAALKAKQEAEAKAQAEKTAAEQAKAEAEAAKKAEGAKVEATKKSAPAVPVMPNSKPKAAAPKAEQPKQEKALDPEKEAKKKEEAELRRKQEELARQKAEMEAKRAAENARRLAEIAREEAAENGEEFEDDRFTSSYAREADRDNDRRSEANRGRGKGGVNKAKKGDREDKNERNADRRNQKDVKGKGKNAKKGSALQQAFTKPVQVNKADVVIGETITVAELANKMAVKATEIIKTMMKMGEMVTINQVIDQETAQLVAEEMGHKVILRNENELEDAVMEDRDVDAEKVTRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETEDGKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHARAAGAPIVVAVNKIDKPEANPDRVEQELLQHEVVSEKFGGDVQFVSVSAKKGLGIDDLLEAILLQSEVLELTAVKEGMASGVVIESYLDKGRGPVATILVQSGTLNKGDIVLCGFEYGRVRAMRDENGKEVDSAGPSIPVEVLGLSGVPAAGDEATVVRDEKKAREVALFRQGKFREVKLARQQKAKLENMFSNMTAGDVAELNVIVKADVQGSVEAICQSLAELSTDEVKVKVVGSGVGGITETDATLAAASNAIMVGFNVRADASARRVIEAENIDLRYYSIIYELLNEIKAAMSGMLQPEFKQEIIGLAEVRDVFRHPKFGAIAGCMVTEGVVKRNNPIRVLRDNVVIFEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVKVGDQIEVFEVVEVKRSI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_MYCGA
Sequence: MLNYFNTALLMVQMILKKQDPSIKFGQMSVNDQGFYLDYLSQTLNINPEDFNKLIKSLAKLCSSAQPISLKTVDLKIANQLLSDQPYLLELINEAKEKTVNLATVDNHHYYLPMAQLVDNTKLVKAFNFQSVGGAYFKGDKDNLVMVRLNGFGFENDKVMQDYLEIIEEQKQRDHRRINKILELFTFNQLAGPGMPIWLPNGQIVRQLIGDYVHSVQKKFGFMAVNTPILGNVDLYKKSGHYNHYAKDMFPELALLDGDKMMLRPMTCPHHCLVYLNKPRNYYDLPMRLSEDALLHRYEASGGLTGLERVRAMTLLDNHIFCRLDQIKTEILNAYQVIKEVIGTFNLKFHRIDLSLHDPNDKQSFIDNEQMWARSENQLEDALKDLGLEYTKQVGEAAFYGPKIDFQVKTALNKIITVSTIQLDFSLPSEEKFDIKYKTKDNTYEQGVIIHLGIIGTYERFVATLLEQTKGALDLWLAPKQAVIIPVNNSVHLEGCNQLLEKLLARDLRVTVDSRDERLNKKIRDHQVNKIPVQIIIGDNELKNPDLITYRLYGQEDSNQLELTKFIELFKKP
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBX2_HUMAN
Sequence: MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530).  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530).  Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity).  Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity).  Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780).
What are the official names of this protein?
Chromobox protein homolog 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localized in distinct foci on chromatin and in chromocenters. Localizes to the inactive X chromosome. Seems to be recruited to H3K27me3, H3K9ac and H3K3me2 sites on chromatin.
Protein: GILT1_DROME
Sequence: MSHKIAAVCLLMSCLIATAYSAAKVPISIYYESLCPDSAKFITEQVYPAVKGELRDVVELTFVPFGKSQFVTQGSEVTFTCHHGPNECYGNKVHACAIEHIQANSYQVEYTRESLTMDFINCLMKAGKNFPDNVYPGQRCASENHINNWENIKTCANSTEGSVLLRKAGESTMRLKEPLTSVPTILFNEQFDKKVNDRAQVNLVGTICQYVSAPQPRICNQHNGASTPSLASVSAILSSLLGLWFIRSFY
What is the function of this protein?
Involved in the immune response to bacterial infection.
What are the official names of this protein?
GILT-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GILT family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_BACSU
Sequence: MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36, BL38, Ribosomal protein B, Ribosomal protein II.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HIS1_PSEPK
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQDDVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYGGQGLYEPLDLQIAQCKLMTAGVVGAAEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLINLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHARIQSLIDTLRAAVESRHRG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR11_STRTC
Sequence: MPITHEQPNGFHSKQLNGSGIAKAKAMPYPSDLLSHFVKQHLELESYKNGQEIEIDGYSLSISAVSAAARYNAPVILRDSSTIRDRLEKARSVIVEKIEGSKSVYGVSTGFGGSADTRTSNTLALGNALLQHQHSGVLPSTTNTLSVLPLLDPIASTSMPESWVRGAILIRINSLIRGHSGVRWELIAKMVELLQANITPLVPLRGSISASGDLSPLSYVAGTLMGNPSIRVFDGPAAFGARQIVSSVKALEEHNITPISLLAKEHLGILNGTAFSASVASLVLSDVTHLAMLAQVCTAMGTEVLLGERMNYAPFIHAVARPHPGQTEAARTIWDLLSGSKLAHGHEEEVTIDQDQGELRQDRYPLRTAPQFLGPQIEDILSALNTVTLECNSTTDNPLIDGETGDIHHGGNFQAMSVSNAMEKTRLSLHHIGKLLFAQCAELVHPDMNRGLPPSLAATDPSINYHGKGIDIGIAAYVSELGYLANPVSTHIQSAELHNQAVNSLALISARATINSLEVLSLLTSSYLYMLCQAYDLRALQADFRQGLAEIVQEELRAHFSAHIESLDESPLFDKVISSMYKELNHTTTMDAVPRMVKVAGASTSLLVDFFMANQTSDAMSVAALTALPKFRETVALRAAAKLVALREEYLLGARGPAPASAWLGRTRPIYEFIRVTLGIRMHGTENLGVFQQGLGVQDVTIGQNVSLIHEAIRDGKMRGVVVGLFA
What is the function of this protein?
Phenylalanine ammonia-lyase; part of the gene cluster that mediates the biosynthesis of strobilurin A, an antifungal polyketide that contains a key beta-methoxyacrylate toxophore that targets the complex III of the mitochondrial electron transport chain (PubMed:30258052).  Strobilurin biosynthesis begins with construction of benzoyl CoA by step-wise elimination of ammonia from phenylalanine by the phenylalanine ammonia-lyase str11, oxygenation by str8 and retro-Claisen reaction to form benzoic acid, which is activated to its CoA thiolester benzoyl CoA by the dedicated CoA ligase str10 (PubMed:30258052).  Benzoyl CoA forms the starter unit for the highly reducing polyketide synthase stpks1 that produces the polyketide prestrobilutin A (PubMed:30258052).  The FAD-dependent oxygenase str9 then catalyzes the key oxidative rearrangement responsible for the creation of the beta-methoxyacrylate toxophore (PubMed:30258052).  Str9 performs epoxidation of the 2,3 olefin of prestrobilutin A, followed by Meinwald rearrangement to furnish the aldehyde intermediate (Probable).  Rapid enolization of the aldehyde intermediate would give the beta-methoxyacrylate skeleton and methylations catalyzed by str2 and str3 complete the synthesis and lead to the production of strobilurin A (Probable).  The short-chain dehydrogenase stl2 and the dehydrogenase str4 play a role in the shunt pathway leading to the production of bolineol (PubMed:30258052).  The cluster encodes no obvious halogenase gene that could be involved in production of strobilurin B, nor any obvious dimethylallyl-transferase that could be involved in the production of strobilurin G (Probable).  It is possible that unknown proteins encoded in, or near, the cluster (such as str1 or stl1) may form new classes of halogenases or dimethylally-transferases, or that the responsible genes are located elsewhere on the genome (Probable).  Similarly, proteins encoded by str5/str6 hydrolases appear to have no chemical role in the biosynthesis of strobilurin A (Probable).  Finally, no obvious self-resistance gene is found within the cluster (Probable).
What are the official names of this protein?
Phenylalanine ammonia-lyase str11, PAL, Strobilurin biosynthesis cluster protein r11.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: PFKA3_STRCO
Sequence: MRIGVLTSGGDCPGLNAVIRSVVHRAVVDHGDEVIGFRDGWKGLLECDYLKLDLDAVGGILARGGTILGSSRVRPEHLRDGVERARGHVEELGLDAIIPIGGEGTLKAARLLSDNGLPIVGVPKTIDNDIAVTDVTFGFDTAVTVATEALDRLKTTAESHQRVLIVEVMGRHTGWIALHSGMAAGAHAVVVPERPFDIDELTAKVGERFSAGKRFAIVVAAEGAKPKAGTMDFDEGGKDVYGHERFAGIARQLSIELEERLGKEARPVILGHVQRGGTPTAYDRVLATRFGWHAVEAVHRGEFGKMTALRGTDIEMVSLADAVESLKTVPDARYAEAECVL
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 3, ATP-PFK 3, Phosphofructokinase 3, Phosphohexokinase 3.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS2_TRYCC
Sequence: MLCLTRLRANVNKVAFMEMVKDLRFRTEAPIAECGAALKETHGDVEKAMEVLRKKGAARAMKKRSRVTEHGSVVACVGGLFGAAVITVCSETDFAARSAQFQNTCARVKDALQRKIIDSKGDVLTNPMEAHRSLVEATAEDIRSSIAVLGENVTIKSVESLRLAPHVAEHISIGSYTHGSLDVPDVGRIAGVVAVSRLDPTREVQASTLTDVARHFVASSGAEGNYAHQNFFGTEETVGQWLKHHGLCFSSSLVVDFGKEPITHTASQPRNAVKHPEG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts 2, mitochondrial, EF-Ts 2, EF-TsMt 2.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BFR_MYCPA
Sequence: MQGDPEVLRLLNEQLTSELTAINQYFLHSKMQDNWGFTELAEHTRAESFDEMRHAEAITDRILLLDGLPNYQRLFSLRIGQTLREQFEADLAIEYEVMDRLKPAIILCREKQDSTTATLFEQIVADEEKHIDYLETQLELMDKLGVELYSAQCVSRPPS
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR, Antigen D.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: ATPA_ZYGCR
Sequence: MVNIRPDEISSIIRKQIEQYTQEVKVVNIGTVLQVGDGIARIYGLDKVMAGELLEFEDGTIGIALNLESDNVGAVLMGDGLTIQEGSSVKATGKIAQIPVSDGYLGRVVNALARPIDGKGDIASSEFRLIESPAPGIISRRSVYEPMQTGLIAIDAMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVNTFEERGAMDYTIVVAETANAPATLQYLAPYTGAALAEYFMYKGQHTLVVYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLGSQLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNSGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFSQFASDLDKATQNQLARGQRLRELLKQAQSAPLSVEQQVATIFTGVNGYLDVIEVSQVRSFLTQLREYIITNKPQFGEIIRSTKTFTDEAQTILKQAIQEHTEAFLLQQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FAD1_CAEEL
Sequence: MRAMFRTPRMPQRKTAAILVIGDEILKGTTRDTNSHFLCKRLHKLGVNIRKISVIGDDISEISREVQSASGAYDYVITSGGVGPTHDDKTYLGLAHAFTDQMQFSDEIRQAVNRFLPTYTAKKRAEGVGEGLEEAVRLATEKLCTIPKMSQLLWGTQKINGSLSTFPVVRISNVVALPGVPKFCERAFDELQDQLFPIEERQSLCFETLYTDLDEFDFSKKLTDLAAQFEDRNVQIGSYPELKNKFFKTKLTIETESSETMEAVVTSLRELLAGHIVYYDSHAWLDIVTKWKAFKKRKASENQIEFIQKLNEAESIVEEIVEKYPLEQIALSFNGGKDCTVLLHLLRLKVDEKYGPSTPIQGFHIMVEDQFPEATQFIIDAAKFYNIQVLEFPGPLKTGLAALKKTRPSIIPVLMGSRATDPNGKYMKTPVEWTDSDWPQVLRVCPILNWTYTDVWHMLRGLCVPYCKLYDQGYTSLGGRDNTVKHPALRIVSSDGREHYLPAYKLHNDAEERCNRSNI
What is the function of this protein?
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
Probable FAD synthase, FAD pyrophosphorylase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
Protein: CTAA_RICCK
Sequence: MQQSLITKWLSISCIMVIAMIVIGGITRLTGSGLSIVEWRPITGILPPLSFEAWQVEFAKYKAFPEYNYVNYRMTLSQFKFIYLLEFIHRLLGRITALIYIVPLIYFYFKGIIKNRDIAPYIIALLLLYVQGFMGWYMVKSGLLNNPSVSHLRLAFHLIIAVIIYHILFYQLIKNRCDILLILSQTDLKLPLRFSSVAITVIYLQIFLGALVAGLDAGLIYNSFPLMGDNFIPTAIKDNFFDLKNWYDPVFIQCIHRLGGYSVFLVVMALATYLLKIEHPKLNKIAYFLIIALLMQISTGIITLLYSVPIIIASTHQFFAIVLLSVIIWCYFLIKTSK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1303_COXBU
Sequence: MISIIIAYATPEKQVEIPLTVEESCTLVVAVKRSGILQQFPEINLSQAIVGIHNKRTALDAGLRDGDRIEIYRPLTMDPKQARLLRAKRGKIRRMVRGEAG
What are the official names of this protein?
UPF0125 protein CBU_1303.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: ABFA_EMENI
Sequence: MPLSAAIKSSLSVSVRADAKGLVGFANTGYNGITVLKQTYWTSFYMKGEYSGTVLLRLTGTDSGTVYGSRNLSVKSTGGKWTQYETTFEANESYVAENEWQLLFDAATAKGHPLHFGLVQLFPPTYKNRTNGLRNDIARPIADLKPKFLRFPGGNNIQADRPGDWHYPNTDALGLDEYLWWCEDMDMVPVLSVWDGKSYGGIVSGEELQPYLDDIKDELEVTLPLTLLSHPLRAYLTPNTNEQYLLGPPSTPFGALRARNGHPDPWPIQYIEIGNEDDYSGGCDTYPDRLVQIYDTIHASYPNLTLIANNMDENCLPEIPLPGLWHDYHYYRSADDLVAMFNYWDNHDRGDRVLVGEYGCRNDSNPDGVFWSFMQGSCAEAVHMIGLERNSDVVMMAAYAPLLQHFGYTQWSVCTPSASLAYLGIHPADRGEEQPTLFGFESRPNSLTLSTSYYVNRMFSTNQGSTVHKVHSTAGFGPLYWVATSNETAYQVKLANYGAANQTVNIRVPGVGRGVLEMISGPKDASNLPGDIKIVPVSRNIRAGKEGYTVHMPPWGVAVLVVVFK
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose.  Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By similarity).
What are the official names of this protein?
Probable alpha-L-arabinofuranosidase A, ABF A, Arabinosidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 51 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_ENTFT
Sequence: MSIITDIYAREVLDSRGNPTIEVEVYTESGAFGRGMVPSGASTGEYEAVELRDGDKARYLGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIDLDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEALRMGAEVFHALASILKGRGLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTEEMIAFYEELVSKYPIISIEDGLDENDWDGFKKLTEVLGDKVQLVGDDLFVTNTTKLAEGIEKGIANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGDVAEYKGLKSFYNLKNK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RPPH_SHEPW
Sequence: MIDSDGFRANVGIIICNRSGQVMWARRFGQHSWQFPQGGVDEGESAEEAMYRELYEEVGLRPEHVQILASTRSWLRYRLPKRLIRQDSKPVCIGQKQKWFLLQLKSSENAIDLNACGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPTTLPLQVKESNHKRRGMRRN
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: GATC_PROMS
Sequence: MTKITKEEVNKVAHLARLELNENEINNHAEQLEKILDYIRQLEKIDTDDVPCTTRAIEVVNVFRKDEKKNSDCNEELLELGPSREDKYFKVPKILNE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CALX_ASPFU
Sequence: MRFNAAITGALVSSATLMGQAHAEETEKKADATSLVEKPTFTPTTIEAPFLEQFTADWDSRWTPSHAKKEDSKSEEDWAYVGEWAVEEPTVLNGMVGDKGLVVKNVAAHHAISAKFPKKIDNKGKTLVVQYEVKPQNSLVCGGAYMKLLQENKKLHAEEFSNATPYVIMFGPDKCGATNKVHFIFRHKNPKTGEYEEKHMTAPPAARTTKLTTLYTLIVKPDQSFQILIDGEAVKNGTLLEDFAPPVNPEKEIDDPKDKKPADWVDEAKIPDPEAKKPDDWDEDAPYEIVDEEATMPEDWLEDEPTSIPDPEAEKPEDWDDEEDGDWIPPTVPNPKCNEVSGCGPWTPPMKKNPAYKGKWTAPLIDNPAYKGIWKPRKIPNPAYFEDKTPSNFEPMGAVGFEIWTMQNDILFDNIYIGHSIEDAEKLRKETFDLKHPVEVALEEASKPKLEEKAATPSVSFKEAPVTYVREKVDYFVGLAKQDPINAVKQVPEVAGGLGALLLTMILVIVGAVGASSPAPAAAAKKGKEAASAAKEKASEAVSSAADTAKGAATKRNTRSSAQ
What is the function of this protein?
Interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity).
What are the official names of this protein?
Calnexin homolog.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: DUT_CROS8
Sequence: MMKKIDVKILDPRVGEQFPLPTYATSGSAGLDLRACLDESVELTPGATTLLPTGLAIHIADPSLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGQLMVSVWNRGQQSFTIEPGERIAQMVFVPVVQAEFNLVEDFTATDRGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CCND3_RAT
Sequence: MELLCCEGTRLAPRAGPDPRLLGDQRVLQSLLRLEERYVPRGSYFQCVQKEIKPHMRKMLAYWMLEVCEEQRCEEDVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAMAPWQLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVLGLGACSMSADELTELLAGITGTEVDCLRACQEQQIEAALRESLREAAQTAPSPVPKAPGGSSSQGPSQTSTPTDVTAIHL
What is the function of this protein?
Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.  Shows transcriptional coactivator activity with ATF5 independently of CDK4.
What are the official names of this protein?
G1/S-specific cyclin-D3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.