PharMolix/UniProtQA huggingface dataset:
Protein: BRLA_PENO1
Sequence: MRTQGQQISDRLTVEVDCHSLGPADCPSMTSSFSPLESPTPTPTSLYSHGSLTSPSWHEAGHYHSLPMERRPSGTPLRNAFRVTDFPSADPMGMQVGTMERPDQLPVSSEYLSGYDDINDQLWIPHDSIPKTFEHPTFPYQAPMPQYHHTMGRNHYYRPQAHTAYLPESASNPCLSRPMFSRHDGLSHSASMSNMLPWMTAPESLAPQTITPQQAFPGAGPVTPPSSNYSDFPASLQTFKPHTPSTPVRSLSLGTPRSDTPQSRMSGHYDYSEEYPVSPVYRDGHLIRTHRQPSRKPSKKQLVRSNLSLEKLPPIIKQVQFKCKEPGCKGRFKRQEHLKRHMKSHSKEKPHVCWVPGCHRAFSRSDNLNAHYTKTHSKRGGRNRYVATLDETSPDYDPEFRGQLTPDGRPIYGSKLEDLADCDLSVDGWED
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:24113825).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity).  Regulates the expression levels of seven secondary metabolism gene clusters including a down-regulated cluster putatively involved in the biosynthesis of the mycotoxins roquefortine C and meleagrin (PubMed:24113825).  Negatively regulates the expression of cellulase genes (PubMed:24113825).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development brlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_STAES
Sequence: MVAKILDGKQIAKEYRQRLKNQVNDLKEYGFTPKLSVILVGNDGASQSYVKSKKKAAEKIGMISEIIHLDESTSEEVVLSELNRLNNDDTVSGILVQVPLPKQVSEQKVLEAINPEKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADINLEGKNAVVIGRSHIVGQPVSKLLLQANATVTILHSRTKNMNAHLKQADVIVSAVGQPGLVTKENVKKGAVIIDVGNTPDENGKLKGDVAYDEVKEIASAITPVPGGVGPLTITMVLNNTLLAEKLRRGLTK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RS16_PROM4
Sequence: MIKLRLKRYGKKREASFRLVACNSTSRRDGRPLEELGFYNPRTKETRLDTEALRTRLSQGAQPTDAVRSLLEKGGLIEKTIRPAEIEGKKKQALARQSASKKAVKEKTEESKGSEVDSETSTSAD
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LYTS_STAS1
Sequence: MLNLFILLLERVGLIILIAYILMNINHFKTMMNEREKRRSQWQLIIIFGCFSMISNFTGIQIRGDEIINGTVYNHLDPDASLANTRVLTIGVSGLIGGPFVALAVAVISGMYRVYIGGADAYIYLISSIFIALISGYFGYKAMRANRYPTIVKGACIGGTTEIIQMLCILLFSDNTEHAWTLVKLIAIPMISINSIGTAIFLSIILSTIKQEEETRAIQTHDVLQLANQTLPYFRSGLNEQSAKKAAEIILNLMRVSAVAITNRKDILTHVGVASDHHVAQKAIITNLSKRAIQSGTLKEAYSSEEIGCNHPGCPLEAAIVVPLRVKNDVVGTLKLYFTNKYDVNYSDKQLATGLAEIFSSQLELGQAETQSALIRDAEIKSLQAQVNPHFFFNAINTISALIRIDSEKARELLLQLSQFFRSNLQGARNNTISLEKELQQVESYLSLEQARYPDRFNVSFDIDRTCYGALVPPFAIQILVENAIKHAFKNRKYNNEIIVKAHKAQTGLVISVSDNGHGIPYEKLDKIGKTSVHSESGTGSALENLNRRLDGLFGYEASLQIHSDHQGTQVSCTIPYHNLEEEKIESNHCR
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensor protein LytS, Autolysin sensor kinase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T2M1_MORBO
Sequence: MKLAFDDFLNSMSETNTTLDYFTDFDKVKKNVAQIEIHLNQLNYLLGKDDLKQAVYDLYAECPNAFSILEILIAVRKKEQKKSLDEKGQVVTLNSYFQSADKIIDFLNNTGLADVFRDKNIKNLVDYVFGIEVGLDTNARKNRGGDNMSKAVQLLFDNADIYYKKEVRNTIFTDIESLGADVKQFDFVIKTKRKTYVIETNYYNSGGSKLNEVARAYTDVAPKINQYSQYEFVWITDGQGWKTAKNKLQEAYTHIPSVYNLYTLHGFIEQLNSEGVIKDW
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3' and cleaves before G-1.
What are the official names of this protein?
Type II restriction enzyme MboI, R.MboI, Endonuclease MboI, Type-2 restriction enzyme MboI.
What is the protein family that this protein belongs to?
Belongs to the DpnII type II restriction endonuclease family.
Protein: ACPS_ANADF
Sequence: MILGLGMDVVEVARIERILAGPPARVDRFLERCFTARERAYCDAARDRATRYAARFAAKEAASKALGAPAGIRFTDVEVVRGAGAPVLELAGVAATAAARLGVRRVLVTLTHDGGVAAATVVLDGEEAR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDCA2_HUMAN
Sequence: MDANSKDKPPETKESAMNNAGNASFILGTGKIVTPQKHAELPPNPCTPDTFKSPLNFSTVTVEQLGITPESFVRNSAGKSSSYLKKCRRRSAVGARGSPETNHLIRFIARQQNIKNARKSPLAQDSPSQGSPALYRNVNTLRERISAFQSAFHSIKENEKMTGCLEFSEAGKESEMTDLTRKEGLSACQQSGFPAVLSSKRRRISYQRDSDENLTDAEGKVIGLQIFNIDTDRACAVETSVDLSEISSKLGSTQSGFLVEESLPLSELTETSNALKVADCVVGKGSSDAVSPDTFTAEVSSDAVPDVRSPATPACRRDLPTPKTFVLRSVLKKPSVKMCLESLQEHCNNLYDDDGTHPSLISNLPNCCKEKEAEDEENFEAPAFLNMRKRKRVTFGEDLSPEVFDESLPANTPLRKGGTPVCKKDFSGLSSLLLEQSPVPEPLPQPDFDDKGENLENIEPLQVSFAVLSSPNKSSISETLSGTDTFSSSNNHEKISSPKVGRITRTSNRRNQLVSVVEESVCNLLNTEVQPCKEKKINRRKSQETKCTKRALPKKSQVLKSCRKKKGKGKKSVQKSLYGERDIASKKPLLSPIPELPEVPEMTPSIPSIRRLGSGYFSSNGKLEEVKTPKNPVKRKDLLRHDPDLHMHQGYDKYDVSEFCSYIKSSSSLGNATSDEDPNTNIMNINENKNIPKAKNKSESENEPKAGTDSPVSCASVTEERVASDSPKPALTLQQGQEFSAGGQNAENLCQFFKISPDLNIKCERKDDFLGAAEGKLQCNRLMPNSQKDCHCLGDVLIENTKESKSQSEDLGRKPMESSSVVSCRDRKDRRRSMCYSDGRSLHLEKNGNHTPSSSVGSSVEISLENSELFKDLSDAIEQTFQRRNSETKVRRSTRLQKDLENEGLVWISLPLPSTSQKAKRRTICTFDSSGFESMSPIKETVSSRQKPQMAPPVSDPENSQGPAAGSSDEPGKRRKSFCISTLANTKATSQFKGYRRRSSLNGKGESSLTALERIEHNGERKQ
What is the function of this protein?
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase.  Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase.  At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
What are the official names of this protein?
Cell division cycle-associated protein 2, Recruits PP1 onto mitotic chromatin at anaphase protein, Repo-Man.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.
Protein: KCNV1_MOUSE
Sequence: MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNLQLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation.  Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily V member 1, Voltage-gated potassium channel subunit Kv8.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 (By similarity).
Protein: Y730_METJA
Sequence: MLKIAWGITGCGDKLPEVVEIMKKLKNKYNLDVDIYLSKNAKIVVKWYKLWQVLEDEFYDLRVEVNANAPFLVGKLQTGKYDLFLVAPATANTTAKIAYGIADTLITNSVAQAMKAKVPVYIFPPDNKKGTVETILPGNKKLTLYMRDVDVENVERLRRMEGIEVLDKPEDIEKVILKHIEVKKQQ
What are the official names of this protein?
Uncharacterized protein MJ0730.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0208.
Protein: PIMT_BURVG
Sequence: MSGERAKRFPLALEDLKRAPRKSDGRAGERHAAIAAPKAADKPAAVPKPVALKPGVARMPPGTAAAKPATALKPTVPKPAMPKPIAANAAPAGAFALTSERVRERMVERLRANGVTDPRVLDAMAAVPRHLFVDAGLATQAYEDSALPIGHQQTISKPSVVARMIELAMAGRTLERVLEIGTGCGYQAAVLSHVARDVYSIERIKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPSAAPFDAIVIAAAGLDVPQALLEQLAIGGRLVAPVGAQSGQPQVLTLIERVAHAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10E_HALSA
Sequence: MSEKPASMYRKIDKPSYTRRDYVTGIPGSKIAQHKMGDLQADADDYPVQISLVPQEECQLRHGSLEAARLSANRHLIKELGEGNYKMQLRKFPHQIIRENKQATGAGADRVSDGMRQAFGVPVGTAARIQPGDQLFTAYCEVEQAAAVKEAFRRAYNKITPPCKINVERGETLLVR
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CYTB_HUMAN
Sequence: MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.  Tightly binding reversible inhibitor of cathepsins L, H and B.
What are the official names of this protein?
Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NU5M_ANOQN
Sequence: MNYLVNYCKISFYFLMSISLSLFLISLKFLLTDLVYFIEWEILSLQSMSIVMTFLFDWMSLMFMSFVLLISSLVIFYSNQYMEEDYNINRFILLVLMFVMSMMMLIISPNLISILLGWDGLGLVSYCLVIYFQNVKSYNAGMLTALSNRIGDVALLLAIAWMLNYGSWNYIFYLDMMKNNIEMMIIGGLVMLAAMTKSAQIPFSSWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFNDVLMNWWMAQFLLLVSGLTMFMAGLGA
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HRCA_MYCPU
Sequence: MNFENKEIKLETKKTILFKNIVELYLRTGKPIGSKFLVEQDYGLGKSSATIRNMMHEFEEIGLLEKSHISSGRIPSTLGLKYYVKYLANSEDSDLKKQLKKLFFQRKLTIDETIELAAKSISEIVGLTMVTSTENSFETLKSIQLVLLDKNESIIIIVLSSGKVISKKLAMKDSIVLDDLRIAVRIFKERLIDTKVSELHEKTLALKPILKISIQNYEDILQEFIINIFDFEVSQTNNVYGKKNIILARDIKREDLTKIIKLIESTSIWQTIEDNLEEEENIKIEIRPDNSSFLSKKISIDNKIREISVVGSKKMDYAKAKSALMLIEDLVEENKKKEKGNNEDNEE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ZN575_HUMAN
Sequence: MLERGAESAAGATDPSPTGKEPVTKEAPHQGPPQKPSQSAPGPTASAGSPPRPRRRPPPQRPHRCPDCDKAFSYPSKLATHRLAHGGARPHPCPDCPKAFSYPSKLAAHRLTHSGARPHPCPHCPKSFGHRSKLAAHLWTHAPTRPYPCPDCPKSFCYPSKLAAHRHTHHATDARPYPCPHCPKAFSFPSKLAAHRLCHDPPTAPGSQATAWHRCSSCGQAFGQRRLLLLHQRSHHQVEHKGERD
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 575.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y427_METJA
Sequence: MMERMHNLNNVYLKECIHFLDSCINALKEFDLRTFISRFYYGMLYLLNAFEFYIRENIEDWHNKDRYANFSKKIRNFLMDLKLYRHASDYILSPRLEHGKHYEEHWEEFKESYLKLKFFHYLHILRQELYSYRHNQLIAIIIEKLEIIEKLLKLYIMLEE
What are the official names of this protein?
Uncharacterized protein MJ0427.
Protein: RPOA_RHILO
Sequence: MIQKNWQELIKPNKIEFSSKKKTLTTLVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIAGVREDVTDIVLNIKEIAIRMEGDGPKRMVVRKQGPGAVLAGDIQTVGDVEILNPDHVICTLDEGAEIRMEFTVDTGKGYVPAERNRAEDAPIGLIPVDSLYSPVKKVSYKVENTREGQVLDYDKLTMTIETDGSISGEDAVAFAARILQDQLGLFVNFDEPQKEVAAEAVTELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLAAMGLHLGMEVPDWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CU095_LOCMI
Sequence: ATVPAGTSVYQQPAVQYQQYQPYQTVVQSQPQQVVAGRVVPAVYPATVGSQVYPSGVVPATVYNSGIVRNVYPAGVVPAVAGAYQYFPTD
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 9.5, LmNCP9.5.
Protein: ATPB_BAUCH
Sequence: MTTGKIIQVIGAVVDVEFPQNIVPKVYNALEVTNGKNKLILEVEQQLGSGIVRCIAMGVSEGLRRGLTVIDLGHAIKVPVGKSTLSRIMNVLGEPIDMKGIINAEEHWSIHRSAPRYEELALSQEILETGIKVIDLMCPLVKGGKAGLFGGAGVGKTVNMMELIRNIAIEHAGYSVFTGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRFRVALTGLTIAEKFRDEGHDVLLFIDNIYRYTLAGAEVSALLGRMPSAVGYQPTLSEEMGLLQERITSTKYGSITSIQAVYVPADDLTDPAPATTFSHLDATIVLSRQIASLGIYPAIDPLESTSRQLDPLVVGQKHYDVALGVQGILQRYQELKDIIAILGIDELSEDDKMVVSRARKIQRFLSQPFFVAEVFTGSQGKYVSLQETISGFEDIINGKYDHLPEQKFYMIGSINEAMTKE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: XRCC1_MOUSE
Sequence: MPEISLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGATAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRIFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPYGLSFVKFHSPPDKDEAEATSQKVTVTKLGQFRVKEEDDSANSLKPGALFFSRINKTSSASTSDPAGPSYAAATLQASSAASSASPVPKVVGSSSKPQEPPKGKRKLDLSLEDRKPPSKPSAGPSTLKRPKLSVPSRTPAAAPASTPAQRAVPGKPRGEGTEPRGARTGPQELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTPDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHHMRRRLPSRRYLMAGLGSSSEDEGDSHSESGEDEAPKLPQKRPQPKAKTQAAGPSSPPRPPTPKETKAPSPGPQDNSDTEGEESEGRDNGAEDSGDTEDELRRVAKQREQRQPPAPEENGEDPYAGSTDENTDSETPSEADLPIPELPDFFEGKHFFLYGEFPGDERRRLIRYVTAFNGELEDYMNERVQFVITAQEWDPNFEEALMENPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA
What is the function of this protein?
Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (By similarity).  Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity (PubMed:28002403).  Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity (By similarity).
What are the official names of this protein?
DNA repair protein XRCC1, X-ray repair cross-complementing protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Moves from the nucleoli to the global nuclear chromatin upon DNA damage.
Protein: BTUD_ECO45
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPANLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PLA21_ORYSJ
Sequence: MPPRSPLLALVFLAAGVLSSATSPPPPPCSRSCAALNCDSVGIRYGKYCGVGWSGCDGEEPCDDLDACCRDHDHCVDKKGLMSVKCHEKFKNCMRKVKKAGKIGFSRKCPYEMAMATMTSGMDMAIMLSQLGTQKLEL
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli.
What are the official names of this protein?
Probable phospholipase A2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_BOVIN
Sequence: MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: FPG_HAEI8
Sequence: MPELPEVETALRGISPYLKNFTIEKVVVRKPKLRWAVSEELITLKNVKIVDLTRRAKYLIIHTEKGYIIGHLGMSGSVRIVPQDSAIDKHDHIDIVVNNGKLLRYNDPRRFGAWLWTENLDDFHLFLKLGPEPLSDEFNAEYLFKKSRQKSTALKTFLMDNAVVVGVGNIYANESLFICGIHPLKLAKNLTRNQCFSLVNTIKDVLRKAIIQGGTTLKDFLQPDGRPGYFAQELLVYGNKDKPCPKCGGKIESLIIGQRNSFFCPKCQKRG
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL281_NOCFA
Sequence: MAAVCDVCAKGPGFGKSVSHSHRRTNRRWNPNIQTVRAQVAPGNTRRMNVCTSCLKAGKVVRG
What are the official names of this protein?
50S ribosomal protein L28 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GRC10_ARATH
Sequence: MKTMRGLRNCSNDAVTLDLTVHPPPPPPLPPPAPSTVSSSTASTSLSFDEEETSESKIGRLISEHPVIIFTRFSSCCMCHVMKKLLSTVGVHPTVIEIDDGEIAYLAVEAAPVLFIGGTCVGGFESLVALHLSGQLIPRLVEVGALWA
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin-C10, AtGrxC10, Protein ROXY 20.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD8B_SAISC
Sequence: MRPRMWLLLSAQLAALHGNSVLQQTPAYIMVQTNQMVMLSCKAISSSTTRIYWLRQLHAPSSNSHHEILAFWDSSKGTIHSEGVEQKKITVFRDGSLFFLNLTRVKLEDSGTYFCMVIGSPTLIFGTGTQLSVVDILPTTAQTTKKSTPKKTVCRLPRPETRKGPLCSPITLSLLVAGILVLLVSLGVAIHLYCRQRRARLRFMKQFYK
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex.  The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.  Once LCK recruited, it initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs).  Additionally, plays a critical role in thymic selection of CD8+ T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD8 beta chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Requires the partner CD8A for efficient cell surface expression. The heterodimer CD8A/CD8B localizes to lipid rafts due to CD8B cytoplasmic tail palmitoylation.
Protein: RL1_CHLSY
Sequence: MPKHGKKYLAALAKVDRTRLYSPTEALALVKETSYTKFDGTVEAHLRLGIDPRHADQNIRTTVALPHGTGKTVRVLVFAQGEAVQAALDAGADYAGSDDLIARIDRENFFDFDVAIATPDMMGKVGRIGRKLGPRGLMPNPKSGTIVPAADLARTIREVKGGRVEIRNDKTGILHVAIGKVSFTPQQLSENFVALMDAVKAAKPSGAKGTYIRSVTLTSTMGPGVPVDPVAAQNLKA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: APAG_XYLFT
Sequence: MENNPSSKIEVAVSSRFLDQQSNRNEGRYVFAYTIRIYNAGNVPARLIARHWQITDANGKVEYVTGEGVIGEQPRLRPGEEFRYTSGVVLGTEQGQMQGHYDMMADDGTEFTATISPFVLSVPRTLH
What are the official names of this protein?
Protein ApaG.