PharMolix/UniProtQA huggingface dataset:
Protein: RS4_LEPCP
Sequence: MARYLGPKAKLARREGTDLYLKSARRSISDKSKFESKPGQHGRTSGSRTSDFGLQLREKQKVKRMYGVLEKQFRRYFAEADRRKGNTGANLLLLLESRLDNVVYRMGFGSTRAEARQLVSHKAVTVNGQSVNIPSYLVKAGDVISVREKSKKQLRIIDALKLADSIGLPAWVSVDLTKMEGIFKKAPDRDEFGAEINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CYB_CROFU
Sequence: MNNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIAQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLNSDTDKIPFHPYYTIKDILGALIMITALSSLVLFSPDMLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIAILMIIPLLHTAKQRSMMFRPMSQCMFWILVADLFTLTWIGGQPVEHPFVVIGQLASMIYFMLILLIMPITSMIENQLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FOLD_MYCGE
Sequence: MSFDGKLKAQSILETYKNFDWSKCKLVIIQANDDDSSDSFIKQKLIACNTVGAKSELIKLSNQITQAELIEKIISLNHDVNVTGIILQLPVYPHLDKNSLLEAINPLKDVDGLTTNHLAEIKPCIVEAIITLKELFNLEFNNQKIVVVGLGITGGKPIYEFLKTSGYKVQACDKDTPNTFELIKSADIVFTAIGKSHFFQAKNFKKGVILFDIGVSRNKQNKLCGDINPEGIEKKARWWTKTPGGVGPFTVLAIIKNLWILHEKNKRCLQSSI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RSMA_ACISJ
Sequence: MKHIPRKRFGQHFLSDQGIIDAIVRAIAPEPGQPMVEIGPGLAALTQPLVERLGRLTVVELDRDLAARLRQHGQLDVIESDVLKVDFAQVAQALNASKIRVVGNLPYNISTPILFHLLAHVRVIADQHFMLQKEVIDRMVAAPATSAYGRLSVMLQWRYAMENVLFVPPESFDPPPRVDSAVVRMVPHEAPEALSMPVLEELVQVAFSQRRKLLRHTLGRWLEARQFAGTFDTQRRAEEVPVSEYVALAQECS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_VIBVY
Sequence: MSRTIMAFDFGTKSIGSAIGQEITGTASPLKAFKANDGIPNWDEIEKQIKEWQPNLLVVGLPTDLHGKALETITPRAKKFAQRLQGRFALPVELHDERLSTTEARSELFSMGGYKALSKGNVDCQSAVIILESWFEAQWG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_XYLFT
Sequence: MSHYEGDLRPAGARFVIVCSRWNARITDALVAGACHSLVDNGVPDDAVDVVRVPGAWEIPIVANLLAQAGQHAAIIALGCVVRGDTRHYEHVADLCAEGMMSVQMQTGVPVLNGVLAVECIKDAEMRAGGSHGNKGAETALAALEMVSLLEKLP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CYSG_SODGM
Sequence: MEYLPLFADLRRRPVLVVGGGEVAARKIQLLMRAGAQIIVAARALCPALEEIRQAGGLSWLGESFEPAMLDDVFLVIAATDDAALNARVSQCAEQRHLLANVVDDQPYCSFIFPSIIDRAPIVVAISSSGTAPVLARILREKLESILPTFLGPMAAIAGAWRGRVKQRIRSMAGRRRFWEKALNGRFASLMAQGRLEQAEQALEQALNAGPEHGGEVALVGAGPGDSGLLTLRGLQLMQQADVVLYDYLVSPEVLELVRRDAERICAGKRVGEHSMPQQEINRLLVTLAQQGKKVVRLKGGDPFIFGRGGEELQAVATAGIPFQVVSGITAAAGATAYAGIPLTHREHAQSITFITGHLRDGADALDWQALARGRQTLAIYMGVVKAAEISSQLIRHGRSAQTPVAVISRGTCSDQYVQTGTLEALDQLAQKAPTPALVVIGEVVALHHEINWFGQQNLAAQKRASVVNLA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: Y2010_LACLM
Sequence: MNTHFTYVLQCADQTLYCGYTTDLEKRLATHNSGKGAKYTKTRLPVKLLASVNFDNKNDAMSCEWWFKHKLVRQQKLKLIKNNLIKEKFLEYLLAKQK
What are the official names of this protein?
UPF0213 protein llmg_2010.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: PRIMA_RAT
Sequence: MLLRDLVLRHGCCWPSLLLHCALHPLWGLVQVTHAEPQKSCSKVTDSCQHICQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPAEDSWWSGLVIIVAVVCASLVFLTVLVIICYKAIKRKPLRKDENGASVAEYPMSSSPSNKGVDVNAAVV
What is the function of this protein?
Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain.  Organizes ACHE into tetramers (By similarity).
What are the official names of this protein?
Proline-rich membrane anchor 1, PRiMA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction. Synapse. Note=In the brain, PRIMA linked to ACHE is found in membrane rafts.
Protein: MSL1_ORYSJ
Sequence: MAPMLSIASRSPSPALIAPHASARATGLRAPFAGNRIVGWGWGDQTKSGTDRNRASICVVLFLRVRSGEPTQAPRDPPAAVGGGGCYVRLPAPPRDRDAVLYHVCLFTLLLCFIPITALAESDIKNLFALRKAIAVGKGFLHNWFELETPPCNWSGISCVGLTVVAIDLSSTPLYVDFPSQIIAFQSLVRLNVSGCGFSGELPEAMVNLQHLQHLDLSDNQLGGPLPASLFDLKMLKVMVLDNNMFSGQLSPAIAHLQQLTVLSISTNSFSGGLPPELGSLKNLEYLDIHTNAFSGSIPASFSNLSRLLYLDANNNNLTGSIFPGIRALVNLVKLDLSSNGLVGAIPKELCQLKNLQSLILSDNELTGSIPEEIGNLKQLEVLNLLKCNLMDTVPLSIGNLEILEGLYISFNSFSGELPASVGELRNLRQLMAKSAGFTGSIPKELGNCKKLTTLVLSGNNFTGTIPEELADLVAVVLFDVEGNRLSGHIPDWIQNWSNVSSISLAQNMFDGPLPGLPLHLVSFSAESNRLSGSIPAKICQGTFLQILRLNDNNLTGSIDETFKGCKNLTELSLLDNHLHGEIPEYLALLPLVSLDLSHNNFTGMIPDRLWESSTILDISLSDNQLTGMITESIGKLLSLQSLSIDRNYLQGPLPRSIGALRNLTALSLSGNMLSEDIPIQLFNCRNLVTLDLSCNNLTGHIPKAISHLTKLNTLVLSRNRLSGAIPSELCVAFSRESHSELEYVQHIGLIDLSRNRLTGHIPRAINNCSILVELHLQDNLLSGTIPVELAELRNITTIDLSSNALVGPVLPWPVPLASLQGLLLSNNRLSGSIPSGIGNILPQITMLDLSGNALTGTLPLDLLCKESLNHLDVSDNNISGQIPFSCHEDKESPIPLIFFNASSNHFSGSLDESISNFTKLTYLDLHNNSLTGRLPSAIARVTSLYYLDLSSNDFSGTIPCGICGMFGLTFANFSGNRDGGTFTLADCAAEEGGVCAANRVDRKMPDHPFHVLEATICCIATAIVIVLVVILVVYLRRRRKMLRRRQFVLVPAGDNAMADHETTLSNNLLGRRRMKKREPPSINLATFEHAPVRVTVDEIMRATGNFDGMHVVGDGGFGTVYRAELPGGRRVAVKRLHGVGRRFQGGEREFRAEMETVGKVRHPNLVPLLGYCAAGDERFLVYEYMEHGSLEDRLRGGGGAALGWPERLTICGGAARGLAFLHHGFVPHVIHRDVKSSNVLLGEGLQPRVSDFGLARIISACETHVSTVLAGTLGYIPPEYALAMRCTAKGDVYSFGVVMLELLTGRPPTWSSAEVTAEGDDERGGGGSLVGWVRWMAARGRGGEVFDACLPVSGAEREQMARVLDVARDCTADEPWRRPTMAEVARRVGAIEAMEYGPLVVAVSSGEPPAMP
What is the function of this protein?
Receptor-like kinase that may play a role male and female sporogenesis.
What are the official names of this protein?
Leucine-rich repeat receptor protein kinase MSL1, MSP1 protein homolog 1, MSP1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: COWN_AZOS1
Sequence: MDSFDAPDRYVSFKGIDCEGNSRRIIDRLHMHIDDPAKTNAFWERFRAKLAIAEDPLKRQADGLCLLCANIYYIADLFEEHDDEDGLAMLRQLEDECC
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: SWI5_SCHPO
Sequence: MEKSQLESRVHLLEQQKEQLESSLQDALAKLKNRDAKQTVQKHIDLLHTYNEIRDIALGMIGKVAEHEKCTSVELFDRFGVNGSE
What is the function of this protein?
Required for normal mating-type switching.  Also involved in the rhp51-dependent recombination DNA repair pathway.
What are the official names of this protein?
Mating-type switching protein swi5, DNA repair protein swi5.
What is the protein family that this protein belongs to?
Belongs to the SWI5/SAE3 family.
Protein: LEXA_SINMW
Sequence: MLTRKQQELLLFIHERMKESGVPPSFDEMKDALDLASKSGIHRLITALEERGFIRRLPNRARALEVIKLPEAYAGNPQVRRGFSPSVIEGSLGKPAAPAPAPKPAPPAENASVVVPVMGRIAAGVPISAIQNNMHDISVPIEMIGSGEHYALEIKGDSMIEAGILDGDTVIIRNASTASIGDIVVALIDDEEATLKRFRRKGASIALEAANPAYETRIFGPDRVKIQGKLVGLIRRYH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: LEUD_CYTH3
Sequence: MEKFITIKSTVVPLPIEDVDTDQIIPARFLKATTKEGFGKSLFCDWRYNQDGTPKADFVMNNPLYSGQILVAGKNFGCGSSREHAAWAIGDAGFRVVVSSFFADIFRGNALNNGILPVQVSDAFLKSIFDAVAANAKQELVVDLANQVISIAGTDLKESFVINEYKKTCLINGYDDIDYVLSIKDKIEAYEKTSKYLSLLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL6_SOLM1
Sequence: MSRIGKREIELPAGVSVELASDAVVVKGPKGQLSTPTHPKIAYAVADGKVQVSRTDDTRVARAQHGLRRTLLANLVEGVSKGFTKTLEVIGVGYKVATAGNTVSLAVGFSHPVDFKLPEGIEAKVEGNKLTLSGIDKVLLGETAARIRRVRPPEPFKGKGIKYENEVIRRKAGKSGGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ATPE_PEA
Sequence: MTFNLCVLTPNRIVWDSEVKEIILSTNSGQIGVLQNHAPIATALDIGILRIRLKDRWLTMALMGGFARIGNNEITILVTDAESASDINPQEAQQTLQIAEANLNKAEGKRETIEANLSLRRAKTRVEAIVETIKRIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TAL_AGRRK
Sequence: MTSKLDQLRAMTTVVADTGDIEAVARLKPVDCTTNPTIVLKALGTPMFADAIKEAVAWGKKQGGTPDAVAAAVADRLAISVGAALSGLVPGRVSTEVDADLSFDTEASLAKARAIIAAYKERGIERDRILIKLASTWEGIRAAEVLQKEGIDCNLTLLFSKAQAVACADAKVFLISPFVGRILDWYKKSTGKDYTPEEDPGVLSVREIYNYYKANDIKTIVMGASFRSAAEVEALAGCDRLTISPNLLDELAKDEGKLERKLSPENKTSVAKIIVDEKTYRWQMNEDAMATEKLAEGIRAFAKDLGTLRAMVSKELQLAAA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_THISH
Sequence: MQVYYDKDADLSIIQGMKVAIVGYGSQGHAHANNLKDSGVDVTVALRAGSASAKKAEGAGLKVQGIEEAVKAADLIMILAPDEHQAALYKNQVEPNLKQGAVLAFAHGFNVHFEQIVPRSDVDVIMIAPKGPGHLVRSTYTKGGGVPSLIAVYQDASGRARDIALSYASANGGGRAGVIETSFKDETETDLFGEQAVLCGGATALVQAGFETLVEAGYPPEMAYFECLHELKLIVDLMYEGGIADMRYSISNTAEYGDITRGPRVVTEQTKAEMKKILTEIQTGKFAREFILENQAGAATLKASRRIAREHPIEVVGAKLRDMMPWIKANKIVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PEPT_SALAR
Sequence: MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVTPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNNIPHGEIKVAFTPDEEVGKGAKHFDVEAFGAQWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPVDEAPETTEGYEGFYHLASMKGTVDRADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAKQQ
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_MYCLB
Sequence: MATYAIVKTGGKQYKVAVGDVVKIEKLDFEPGAKVSLPVTLVVDGATVTTNAKALAKVAVTGKVLEHTKGPKIRIHKFKNKTGYHKRQGHRQQLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ANGP2_BOVIN
Sequence: MWQLVFLTLSCDLAVATAHSGSRKGMDIAAGKKQYQVQHGACSYTFLLPETDHCRSPSSAYVPNAVQRDAPLDYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEISKLQDKNSFLEKKVLDMEDKHIVQLRSIKEEKDQLQVLVSKQNSIIEELEKQLVTATVNNSVLQKQQHDLMETVNNLLTLMSTSNPSYSLLAKDEQIIFRDCGEAFKSGLTTSGVYTLTFPNSTEEIKAYCDMETGGGGWTVIQRREDGSVDFQRTWKEYKVGFGNPSGEHWLGNEFVSQVTGQKRYVLKIHLRDWEGNEAYSLYDHFYLSNEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDADNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
What is the function of this protein?
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling.  Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.  In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.  In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.  Involved in the regulation of lymphangiogenesis.
What are the official names of this protein?
Angiopoietin-2, ANG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_GLUOX
Sequence: MPLYESVLIARNDVSQAQVETLVETIETLLKDNGGSIQKREFWGLRSLAYRIKKNRKGHYVLLGLDCTPDTLRELERQLGLNEDVLRVLTLRVDEIDENPSSVLARKSDDRGDRGNFRGGSKPAGRFESGRGGPRRSSEDREEYRARGEQDDARETAGAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DMAW_CLAFS
Sequence: MMTKAPATAVYDTLSLLFDFPNQEQRLWWHSIAPMFAAMLDTAGHNVHDQYRHLGIFKKHIIPFLGVYPAQGKHTWPSVLTRYGIPFELSLNCLDSVVRYTFEPTTEHTGTGDDSYNAFAILECIQKLVRIQPGIDMEWFSYFRNELVLNATESARLGRNDSVNQQPIRTQNKLALDLKGDRFALKVYLYPHLKSIATGVSSHDLIFNSVRKLSQKHTSIQPSFNVLCDYVASRNDPDSNAAEAEAGVPASALRARLLSCDLVDPSKSRIKIYLLEQTVSLTAMEDLWTLGGRRTDSSTLNGLDMMRELWHLLQIPSGFMKYPESDLKLGEVPDEQLPSMVHYALHPDQPMPEPQVYFTVFGMSDAGITNALATFFSRHGWYEMAKKYRVFLEGSFPNHDFESLNYLHTYVSFSYRKNKPYLSVYLHSFETGQWPAFSDDPTAFNAFKRCDLSLT
What is the function of this protein?
Tryptophan dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:7488077, PubMed:17720822, PubMed:1605639).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:7488077, PubMed:1605639).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (By similarity).  Agroclavine dehydrogenase easG then mediates the conversion of chanoclavine-I aldehyde to agroclavine via a non-enzymatic adduct reaction: the substrate is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione (By similarity).  Further conversion of agroclavine to paspalic acid is a two-step process involving oxidation of agroclavine to elymoclavine and of elymoclavine to paspalic acid, the second step being performed by the elymoclavine oxidase cloA (PubMed:17720822).  However, cloA does not encode a functional enzyme indicating that C. fusiformis terminates its ergot alkaloid pathway at elymoclavine (PubMed:17720822).
What are the official names of this protein?
Tryptophan dimethylallyltransferase, 4-dimethylallyltryptophan synthase, DMATS, All-trans-hexaprenyl-diphosphate synthase, L-tryptophan dimethylallyl transferase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: GLD3_CAEEL
Sequence: MGEQSHEKDHDEAHSYNPFVRSAVEYDADTRLQMAENAASARKLFVSSALKDIIVNPENFYHDFQQSAQMAEDANQRRQVSYNTKREAHIHQLKAQGLPLPSNIPMIEINPTRVTLNMEFESQYYSLMTSDNGDHENVASIMAETNTLIQLPDRSVGGTTPDPFAQQVTITGYFGDVDRARMLMRRNCHFTVFMALSKMKMPLHELQAHVRQNPIQNVEMSFVDAPEKNGIVTTYLRITAREKNQHELIEAAKRLNEILFRESPAPENNFTLHFTLSTYYVDQVLGSSSTAQLMPVIERETTTIISYPCYNNRNETRGNIYEIKVVGNIDNVLKARRYIMDLLPISMCFNIKNTDMAEPSRVSDRNIHMIIDESGIILKMTPSVYEPADLLSGEVPLNCASLRSKEFNIKKLYTAYQKVLSKKFDFIAPQPNDYDNSIWHHSLPANFLKNFNMPCRGELSDGSNGRRHRSSSIASSRSKHSYMSKGKQFSESSGGPSRSHTRVSSFSENSSTVPIMQFPTPHFAPPMLTPHHHMLKYVYLQQHQQAQTFLKGAAGLHPGTHIMFPPPIIVDGSFVSALPFADPVVFDGFPYVHGLFPVNEAEQHRNHRESSPSLRSTQEIRKPSRNMGNRPSSSTGSYYPSTTPRQRVYEQVREDDLRSHIGSRRTSVNGDDQNVESMHDQGYERQYPRQHQRLQKDDQQRWKTGSRGDIHSSRTINVHRDVRNSNEYDFHVGNSGPAKRSPSLEQVQLQMTHHLKLKSNDVDLDHEKLYMHESPHNDSDTTVSASGFGNDLMDGDFVQRFLSNANINESGRRPRTVSCFTEKDGQSARYIDSDGAYSVVDHASTHQSRSYDSFRKVGDNGVTKTILEPRARVEKDYGKISLEHKTKYSNEYGDEEKSAENDTSSLGSRQYRIDPMKLIASVRESSEQLPRIHERQFSDVLNEKEKEIADKSIESTVTQDLSLDETSTY
What is the function of this protein?
Required maternally for germline survival and embryogenesis.  Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors.  Promotes maturation of primary spermatocytes to mature sperm.  Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm.  Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf.  Required during male development for the continued production of sperm and inhibition of oogenesis.  Together with gld-2, promotes the transition from mitosis to meiosis.
What are the official names of this protein?
Defective in germ line development protein 3, Germline development defective 3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule. Cytoplasm, perinuclear region. Note=Localizes to P granules. Found also in particles near but not coincident with P granules.
Protein: SAU67_ARATH
Sequence: MMINAKKLMKMAKKWQQRAALHRKRISFQRSNVFTSSSSTVEKGCFVVYTADKIRFAFPISYLSNSIVQELLKISEEEFGLPTEGPITLPFDSVFLEYLIKLIQRRMDGDTEKALLMSISSAKCSLQCSLLQQEQSTQQLLVL
What is the function of this protein?
May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
What are the official names of this protein?
Auxin-responsive protein SAUR67, Protein SMALL AUXIN UP RNA 67.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HDFR_SALPK
Sequence: MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLHTVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RIHA_SALTY
Sequence: MALPIIIDCDPGHDDAIALVLALASPELEVKAITSSAGNQTPEKTLRNVLRMLTLLKRLDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSGTAVELMAKTLRESAQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMALGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRAIGNPISTIVAELLDFFMEYHKDEKWGFVGAPLHDPCTIAWLLKPEIFTTVERWVGVETQGKYTQGMTVVDYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: RL11_GEOTN
Sequence: MAKKVIKIVKLQIPAGKANPAPPVGPALGQAGVNIMAFCKEFNARTADQAGLIIPVEITVFEDRSFTFITKTPPAAVLLKKAAGIESGSGEPNRNKVATIKRDKVREIAELKMPDLNAASIEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.