PharMolix/UniProtQA huggingface dataset:
Protein: H2B1_CAEEL
Sequence: MPPKPSAKGAKKAAKTVTKPKDGKKRRHARKESYSVYIYRVLKQVHPDTGVSSKAMSIMNSFVNDVFERIAAEASRLAHYNKRSTISSREIQTAVRLILPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B 1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SECA_RALSO
Sequence: MITGLLKKIFGSRNERLIKQYRRKVVQINALEPTFEALSDAELQAKTQAFRERFAKGETLDALLPEAFAVCREASKRVMKMRHFDVQLIGGMVLHDGKIAEMRTGEGKTLTATLAVYLNAIAGLGVHVVTVNDYLAQRDAEWMGKLYNWLGLSVGVNLTTMAHDEKQAAYAADITYGTNNEFGFDYLRDNMVYDDSQRVQRPLNYAIVDEVDSILIDEARTPLIISGQAEDHTDLYRRMNSIPPLLTRQIGEEKADGTGVEKPGDYYVDEKSHQVYLTEAGHEKAEQILLQAGLLAEGESLYAPQNITLMHHLYASLRAHSLFHRDQHYVVQGDEVIIVDEFTGRLMQGRRWSDGLHQAVEAKEGVQIQQENQTLATITFQNYFRMYAKLAGMTGTADTEAYEFQEIYGLETVVIPTNRQAQRKDLQDQIYKTSKERYDAVIRDIRDCFERGQPVLVGTTSIENSELLSHLLNQAQLPHQVLNAKQHAREAEIVAQAGRPKMVTIATNMAGRGTDIVLGGNVEKQAGFVMADESLSDEEKARRVTQLQDEWQSLHEQVKAAGGLHIVGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDQLLRIFAGDRVRAIMDRLKMPEGEPIEAGIVTRSIESAQRKVEGRNFDIRKQLLQYDDVANDQRREIYKLRNEILEAVDAGDLVKNLRESVFVELFRAYVPAESMEEQWDLAGLEKTLRDDWGVEVPLVKTVEQAQSIEDEELLTQVQEAVEAVYAGKVAQVGRESFAGFERSVMLQSLDTHWREHLAALDHLRQGIHLRGYAQKDPKQEYKRESFELFGRLLDNIRNEVTRIIFTVRIQSQAELEEASEQIEEDLSQLTNVQYKHDEFSELAEVAAGDAEIHGETPPVPAHRSAAASAAAALAGQVPKVGRNDPCPCGSGKKYKQCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DHPH_LYSSH
Sequence: MAKQLEKSSKIGNEDVFQKIANHEQIVFCNDPVSGLQAIIAIHDTTLGPALGGTRMYPYKNVDEALEDVLRLSEGMTYKCAAADIDFGGGKAVIIGDPEKDKSPALFRAFGQFVESLNGRFYTGTDMGTTMDDFVHAQKETNFINGIPEQYGGSGDSSIPTAQGVIYALKATNQYLFGSDSLSGKTYAIQGLGKVGYKVAEQLLKAGADLFVTDIHENVLNSIKQKSEELGGSVTIVKSDDIYSVQADIFVPCAMGGIINDKTIPKLKVKAVVGSANNQLKDLRHANVLNEKGILYAPDYIVNAGGLIQVADELYGPNKERVLLKTKEIYRSLLEIFNQAALDCITTVEAANRKCQKTIEGQQTRNSFFSRGRRPKWNIKE
What is the function of this protein?
Catalyzes the reversible NAD(+)-dependent oxidative deamination of L-phenylalanine to phenylpyruvate.
What are the official names of this protein?
Phenylalanine dehydrogenase, PheDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: YIHY_SHIDS
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MK16B_XENLA
Sequence: MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEFNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERLKQGAYGDIYNFPIQAFDKALEQQDEASASESSDEEEEDDEESGKREFVEDDDVEESDLSDFEDMDKLGASSDEDKPSSESEEESSGEEDEKEEKAPKAKSKGKAPLKGHLIRKRPHVEIEYEQETEPQQKAKVT
What are the official names of this protein?
Protein MAK16 homolog B, MAK16-like protein B.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PVK3_BLAGE
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, BlaGe-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_KINRD
Sequence: MTMALSTQRTTKGKAASLKRRHTRVRKKVVGTAVRPRLVVTRSTRHVFVQVIDDAAGHTLASASTMEADLRASGDDKSAKAKAVGVLVGERAKAAGIDAVVFDRGGNRYAGRVAAIADGAREAGLAL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HEM3_CLOBA
Sequence: MNELIIATRKSKLAQVQTEIIMSELKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFVKDIELALLNKEAHAAVHSMKDVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGAKVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQNLDGIVLAAAGLKRLGDENLITDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHSLIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PROB_LISMC
Sequence: MRESLKNSKRLVIKVGTSTLMYGNGHINLRTIEKLAMVLSDLRNEGKEVILVSSGAIGVGCHKLQLSVRPTSIPDLQAVASVGQSELMHIYSKFFGEYGQVVGQVLLTRDVTDFPISRENVMNTLDSLLSRGIIPIVNENDTVAVEELEHVTKYGDNDLLSAIVAKLVQADLLIMLSDIDGFYGSNPATDPEAVMFSEINQITPEIEALAGGRGSKFGTGGMLTKLSAASYCMDSNQKMILTNGKNPTVIFNIMQGEQIGTLFASKKEELSHDRTH
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY2_AGRFC
Sequence: MADINPRQSDTSKFPDPVYKETVLRPLFDGAKNHHVDGFRRIDRAHLVMLRETGILDAETAAKIAGALEDIDRTIEPSELVYTGEVEDFFFLIEKELKARIGVDVAGRLHTARSRNDIDHTLFKIGLKDKIDTLTAKARVLLKALIDAAERNQSTLIVAYTHGQPAQPTTFGHYLSAAIEVLIRDIERFTEARHIVDLSPMGAAAITTSGFPIDRARVAELLGFAAPLRNSYSCIAAVDYTTATYGAIELMFLHLGRLIQDFQFWTSFEVGQIYVPNSLVQISSIMPQKRNPVPIEHLRHLASQTFGRARTMLDVMHNTPFTDMNDSEGETQSMGYEAFASAGRVLDLLASLVGQISIDPERVDQNIRRSCITITELADSLVRIEDLSFRQAHEIAATVAKSVVALKGDLPNDGYQPFLGAFSGLTGRETGIDEEKFRQIVSPEHFVAVRSRFGGPAPEPMREAFAAYRGKLGAFEAEAQRSTNHEAAKAAELAEKFTALTGAR
What are the official names of this protein?
Argininosuccinate lyase 2, ASAL 2, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_BORPA
Sequence: MPARLDARATRRYFDSAFNSPAVKILPNEYYVTNGEDVMLSTVLGSCVAACIHDPVIGVGGMNHFMLPEGDIHSPASATMRYGAFAMEVLINELLKAGAVRERLEAKVFGGGAVLSAMQLMNIGERNGQFVLNYLKTEGIPVRAQDLGDVHARRINYFPRDGRVMVRKMAPHHQKAEALIAQREAAAAQTVQAETRAAPRVERFARPGGMPV
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: UBP4_SCHPO
Sequence: MSDDYFDRLFELAFVYINEDETIQSCSFRGQRWLEEAQTLEQKNSLLKAYYYYLKALKLAYEIPCRFEISVKSTHYGEFKQFQKLAIQAVSKAFTIKSKLAVKHYLPVIQISDALSLSKKSSLKVLFLNFYSQESSKGYVFSKHTIAIPISCLQSMDSSKIYDFLKSAPFHPSMVICYSLERYFEDVSLAYKLYSMLRSLKLDPHFMELANPKKVDSSLSYENYQPIGLTNLGNTCYMNCVLQCLFACKDLTIPMLQGRGLLQNINTKNPLGTGGKITSAFFSLLQSVLLNHGQRSISPRNFLEIVQSLNRDFSIDGQCDAQEFLNFFLDKLHEDLNSNASRSPIAPLTEDQLSAREELPLSHFSHIEWNLHLRSNKSIVVNNFVGQLCSRTQCMTCGRTSTTFAPFTSLAIPIDDVSHVVSLQECLLKFSAPELLQGHDGWHCPVCKVQRSAKKVIMISKLPEYLIIQIQRFKISVMGRKKIDTPLGLSLQIPSKMLVPPSFQSGIGYIPSNYNLFAFICHYGQLENGHYISDVLFNNEWCHIDDSIVRTVGGITDLREDFSSSYILFYKRSSLLEEFEDKCPKMTLKRNVK
What is the function of this protein?
Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety.  Acts late in the proteolytic pathway in conjunction with the 26S proteasome.  Plays a role in avoiding DNA overreplication (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: MSRQ_KLEP3
Sequence: MRFTVKQIAWLKVFLHLAGFLPLVWLFWAGHQGYFSADPAKDIQHFTGRMALKFLLATLLVAPLARYAKQPLLIRIRRLLGLWCFAWATLHLTSYTLLELGINNLALLGSEIINRPYLTLGMICWVILLALAATSTQAMQRKLGRRWQLLHNFVYLVAILAPIHYLWSVKIVSPQPIIYALLAVVLLACRYKKFRQWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YACG_BRUA2
Sequence: MAPLRPTRPCPECGKPSTREAYPFCSPRCKNIDLNRWLSGSYVIAGKPLGEEDENDS
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RFT1_MOUSE
Sequence: MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTTFLAREAFRRACLSGGAQRDWSQTLNLLWLTVPLGIFWSSCLGWVWLQLLEVPDPDVVPYYGTGVLFFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTTVLVLCYAIYLIQLLRSPESAKQLTLPVSRVTQLLPSISRSRAFVNWKEAGLAWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPVEESFYLFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTMTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAINGVTECFMFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFRESPHRPLAGLRLSPVLLGVFILSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLSDKMT
What is the function of this protein?
May be involved in N-linked oligosaccharide assembly.  May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane (By similarity).
What are the official names of this protein?
Protein RFT1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCES_ASHGO
Sequence: MALRPEKPVWMSQEQYDRQYGKLEEPKPPREESKPGDQAKPSAEPKSGSEEKTEGSSSSTGQGEERPHFKIQKRRHQNYDLEERKKKQQLNKLREEQLKQHDIEMAANKVVNVDQIVREHYNERTFHAKRYNRNYSPIIKLRNFNNAIKYMLIDKYTRPRDVVLELGCGKGGDLRKYGACEISQFIGIDISNESIREAQRRYLNMRDLDYQVILITGDCFGESLGVAVQPFPECRFPCDVVSTQFCLHYAFETEEKARRAILNVSKSLKVGGFFFGTIPDAEFIRYKLNKFSKEVERPSWGNSIYKVVFANNSYQLNDYEFETPYGNMYTYWLEDAIDNVPEYVIPFETLRNLCDEYGMELEMQKPFNKFFVEEIPQWMNKFSPRLREGLQRSDGKYGVEGDEKEAASYFYTVFAFRKVKDYVENAPAHA
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_PSEPK
Sequence: MNINATLIGQSVAFLIFVLFCMKYVWPPVITALQERQKKIADGLDAANRAARDLELAQEKAGQQLREAKAQAAEIIEQSKKRAAQLVDEAREQARVEADRVKAQALAEIEQELNSAKDALRAQVGALAVGGAEKILGATIDQNAHAELVNKLAAEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NFUA_VIBVU
Sequence: MSNITITEAAQTHFANLLGQQPDGTNIRVFVVNPGTQNAECGVSYCPPEAVEATDTEIPYQSFSAYVDELSLPFLEDAEIDYVTDKMGSQLTLKAPNAKMRKVADDAPLLERVEYAIQTQVNPQLAGHGGHVKLMEITDAGVAIVAFGGGCNGCSMVDVTLKEGIEKELLQQFSGELTAVRDATEHDRGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: NUOB_DEHMB
Sequence: MELNFEKPLSLLTLDEIDQQEGGVIQSFRTGHTSPYPDPADWLNGEEPPPGVFITSVEKVLNWSRHYSLWPVMFGLACCAIEMMCMAASRWDLARFGMDIFRASPRQADLMIVAGTLTWKMAPWLKRIYDQMPEPKWVLAMGACGTSGGLFRDSYSVVPGFNLVVPVDVYVPGCPPRPEALMRAIMDIHEKIDKTCILKR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YD286_YEAST
Sequence: MLRAFRCSIHTSRVLLHDAGVKLTFFSKPNCGLCDQAKEVIDDVFERKEFHNKAVSLEIVNITDRRNAKWWKEYCFDIPVLHIEKVGDPKSCTKILHFLEEDDISDKIRRMQSR
What are the official names of this protein?
Glutaredoxin-like protein YDR286C.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. YDR286C subfamily.
Protein: DEOB_PHOLL
Sequence: MKRTFIMVLDSFGIGASKDAEKFGDQGSNTLGHIAEACARGDADIGRKGPLYLPNLSRLGLGKATEESCGTFPAGLDKDADIIGAYAYASELSSGKDTPSGHWEIAGVPVLFDWGYFKDEENSFPQALLDKLVERANLPGYLGNCHSSGTVILDKLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDRLYELCEIAREELTDGGYNIGRVIARPFVGDKAGNFQRTGNRHDLAVEPPAPTILKKLVDEKNGEVVSIGKIADIYANVGITQKVKATGIDALFDATLVEMEKAGDNTIVFTNFVDFDSSYGHRRDVPGYAAALELFDRRLPEMLKRVKNDDILILTADHGCDPTWSGTDHTREHIPVLIYGPKVQPGSLGHRETFADIGQTVAKYFELSPMEYGKSML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_STAA9
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADI_YERPB
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF18_ARATH
Sequence: MAKFCTTITLILVALVLFADFEAPTIVKAELCKRESETWSGRCVNDYQCRDHCINNDRGNDGYCAGGYPWYRSCFCFFSC
What is the function of this protein?
Confers broad-spectrum resistance to pathogens.
What are the official names of this protein?
Defensin-like protein 18, Cysteine-rich antifungal protein At1g55010, Plant defensin 1.5.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSI_ACTPJ
Sequence: MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILDDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKVESSDDLLKIEDEPILGKTYLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDENGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTVQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCRRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: YKUD_ALKCK
Sequence: MFFHSVQQGETLSSIAADYRISLSHLIQANPTINPNQLFVGQSIVIPGLPNPNTIPYEIHVSLSQHQLTLLHNGSVVKIYPIAVGKMLTQTPTGNFVIVNKAPNPGGPFGTMWMSLSKLHYGIHGTNDPSSIGKSVSHGCIRMHNKDVEELAATVPIGTRVRIEP
What is the function of this protein?
Probable enzyme that may play an important role in cell wall biology.
What are the official names of this protein?
Putative L,D-transpeptidase YkuD, Spore protein YkuD homolog.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Spore wall. Note=Probably localized either on the surface of the outer spore membrane and/or in the inner spore coat.
Protein: SAHH_RHOPA
Sequence: MTAKFTDYIVKDIGLAEFGRKEISLAETEMPGLMATREEYGPKQPLKGAKIAGSLHMTIQTAVLIETLVALGAEVRWVSCNIYSTQDHAAAAIAAAGIPVFAVKGETLKDYWDYTAKLFDWSDGGTPNMILDDGGDATMFVHQGLRAENGDTMFLDQHNSEEEEIFFALIKRILKEKPKGYFATLAKNIKGVSEETTTGVHRLYDMEKAGKLLFPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYQVVTMEDAAPIADIFVTATGNKDIITIEHMRAMKDRAIVCNIGHFDNEIQVATLKNMKWDNIKPQVDEITFPDGKRMILLSEGRLVNLGNAMGHPSFVMSASFTNQTLAQIELFQNQGKYEKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKVEGPFKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_STRPB
Sequence: MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: T161A_HUMAN
Sequence: MAVLGVQLVVTLLTATLMHRLAPHCSFARWLLCNGSLFRYKHPSEEELRALAGKPRPRGRKERWANGLSEEKPLSVPRDAPFQLETCPLTTVDALVLRFFLEYQWFVDFAVYSGGVYLFTEAYYYMLGPAKETNIAVFWCLLTVTFSIKMFLTVTRLYFSAEEGGERSVCLTFAFLFLLLAMLVQVVREETLELGLEPGLASMTQNLEPLLKKQGWDWALPVAKLAIRVGLAVVGSVLGAFLTFPGLRLAQTHRDALTMSEDRPMLQFLLHTSFLSPLFILWLWTKPIARDFLHQPPFGETRFSLLSDSAFDSGRLWLLVVLCLLRLAVTRPHLQAYLCLAKARVEQLRREAGRIEAREIQQRVVRVYCYVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLGPAPLLSPDPSSASAAPIGSGEDEVQQTAARIAGALGGLLTPLFLRGVLAYLIWWTAACQLLASLFGLYFHQHLAGS
What is the function of this protein?
May play a role in protection against oxidative stress.  Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis.
What are the official names of this protein?
Transmembrane protein 161A, Adaptive response to oxidative stress protein 29, AROS-29.
What is the protein family that this protein belongs to?
Belongs to the TMEM161 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLHA_CTEID
Sequence: MFWTRYAGASILLFLMLIHLGQVYPRNDMTNFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEVKRVLVNDVKLVNHTDCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of heterodimeric glycoprotein hormones.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.  Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Glycoprotein hormones alpha chain, GTH-alpha, Gonadotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.