PharMolix/UniProtQA huggingface dataset:
Protein: MEPA_ECOK1
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPALWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y4VR_SINFN
Sequence: MAGLGQIAFGCEGGIDTCTAAQNTLAVFFDLGPKVGSVGRNLKSNSGRFILEPMPRDSAPAWYAIIRDFDADVPWRLKAFHTAAGLAIEPSVRSVYEGFAVLLTTGQSRIDRTPSVSLPIGSSLETEAITAIHAPKWRG
What are the official names of this protein?
Uncharacterized protein y4vR.
Protein: NAS2_ORYSJ
Sequence: MEAQNQEVAALVEKIAGLHAAISKLPSLSPSAEVDALFTDLVTACVPASPVDVAKLGPEAQAMREELIRLCSAAEGHLEAHYADMLAAFDNPLDHLARFPYYGNYVNLSKLEYDLLVRYVPGIAPTRVAFVGSGPLPFSSLVLAAHHLPDAVFDNYDRCGAANERARRLFRGADEGLGARMAFHTADVATLTGELGAYDVVFLAALVGMAAEEKAGVIAHLGAHMADGAALVVRSAHGARGFLYPIVDLEDIRRGGFDVLAVYHPDDEVINSVIVARKADPRRGGGLAGARGAVPVVSPPCKCCKMEAAAGAFQKAEEFAAKRLSV
What is the function of this protein?
Synthesizes nicotianamine, a polyamine that is the first intermediate in the synthesis of the phytosiderophores of the mugineic acid type found in gramineae which serve as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
What are the official names of this protein?
Nicotianamine synthase 2, S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 2, OsNAS2.
What is the protein family that this protein belongs to?
Belongs to the nicotianamine synthase (NAS)-like family.
Protein: YAJQ_ECO7I
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: Y1356_STRP3
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYGIHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYITIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein SpyM3_1356.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: NUDL_ESCF3
Sequence: MEYSSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDTSVIAAALREAEEEVAIPPSSVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYHASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEHYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: WBKC_BRUA2
Sequence: MAIAPNTRVLVAGYGLPAEFCVTTLIGMGVEIDKIAVATHREDNRNCGLHSMLRLRNIQFTTAAANSEEFYEFGANFDPDMIISMHYRSLIPGRFLKLAKKGSVNLHPSLLPAYRGTNSVAWVIINGESETGFSYHRMDENFDTGAILLQERISVEETDTAFSLFHRQIARAMLRLEEVILKLDQGDPGFAQLGEASYYARELPFGGVIDPRWSEVQIDRFIRAMFFPPFPPAVLKIDGKVYYVPSIDIYRSLMRGIPS
What is the function of this protein?
Involved in the lipopolysaccharide (LPS) O-antigen biosynthesis (PubMed:20580469).  Catalyzes the transfer of a formyl group to GDP-perosamine, leading to the formation of GDP-N-formylperosamine (By similarity).  Is critical for full bacterial virulence (PubMed:20580469).
What are the official names of this protein?
GDP-perosamine N-formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ICAR_STAAE
Sequence: MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
What is the function of this protein?
Represses transcription of the icaADBC operon necessary for biofilm production.
What are the official names of this protein?
Biofilm operon icaADBC HTH-type negative transcriptional regulator IcaR, Intercellular adhesion protein R.
Protein: GRFA_MYXVL
Sequence: MVPRDLVATLLCAMCIVQATMPSLDNYLYIIKRIKLCNDDYKNYCLNNGTCFTVALNNVSLNPFCACHINYVGSRCQFINLITIK
What is the function of this protein?
Stimulates the growth of some tissues.
What are the official names of this protein?
Growth factor, Secreted epidermal growth factor-like.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBM_BUXMI
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EUPR_PHOSX
Sequence: MFSTEPRSDTAPGSPSCSETKRRKVRRGTHSCWECKRRKVKCSYSNPSDPRCIGCRRRGTKCLSQQDVDEGASVVSAAVDEDRRIGDRMVRVEALIEQLANQVVNRESEKVVGTNDSESDLATSCSPQDTQTLKHLLPQKVNSPSTCIEYAPVSAALHAALPPHEDINLIIKAGLDVSLHRLMTTSLATLSRCIDGFRAGLAEIPSVDTHPTLLARYLLILATCLQAAHPELHAKEIRCLSEPPRLAMRRLVNAATDLVTSKDELLSSVEGLECVMLESLYLANDGNLRRAWLVCRRAMAVAQLLGLHRVDSQQLPCLTFLSQSVDPRFLWFRIVCTDRQLCLMLGLPQGTPDVSMATESALANDSASGRFERKQCVIASRILERNEASGDFTNDDLATVLKLDEELQQAANEMPSSWWLVPNLASSLHDQNKTIWEMLRLIEQMLYFNLLNLLHLPCMLRARQPA
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of eupenifeldin, a bistropolone meroterpenoid that acts as an antitumor agent.
What are the official names of this protein?
Transcription factor eupR, Eupenifeldin biosynthesis cluster protein RT.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELU_SHISS
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLYAAGIDYPLVEGGYKALRQAAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTDSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKTQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: RNAS6_PIG
Sequence: MGPDLRCFPLLLLLLGLWWSVRPLCAIPKNLTRAQWFTIQHIQPSPLQCNKAMNSVNNYTWHCKPQNTFLHDSFQDVATACNLPNITCKNGQNNCHQSAKPVSLTQCSFTGGNYPNCRYKDAAQYKFFIVACDPPQKGDPPYPFVPVHLDKII
What is the function of this protein?
Ribonuclease which shows a preference for the pyrimidines uridine and cytosine (PubMed:7764367).  Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P. aeruginosa, A. baumanii, M. luteus, S. aureus, E. faecalis, E. faecium, S. saprophyticus and E. coli (By similarity).  Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria (By similarity).  Probably contributes to urinary tract sterility (By similarity).  Bactericidal activity is independent of RNase activity (By similarity).
What are the official names of this protein?
Ribonuclease K3, RNase K3.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Cytoplasmic granule.
Protein: METN1_PSEPK
Sequence: MIEFQQVHKTYRVAGREIPALNPTSLTIEDGQVFGLIGHSGAGKSTMLRLINRLEEPSGGTIIVDGEDVTAFNASQLRGFRQQVGMIFQHFNLLASKTVADNVALPLALAGELSRSEIDKRVTELLARVGLSDHAKKYPAQLSGGQKQRVGIARALSTNPKILLCDEATSALDPQTTASVLQLLAEINRELKLTIVLITHEMDVIRRVCDRVAVMDAGQIVEQGSVAEVFLHPQHPTTKRFVQEDEQVDEGEQRDDFAHVPGRIVRLTFQGDATYAPLLGTVARETGVDYSILAGRIDRIKDVPYGQLTLALIGGDMEAAFARFKAADVHMEVLR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ABP_POPEU
Sequence: KGDIMVFPR
What is the function of this protein?
Probable receptor for the plant growth-promoting hormone auxin.
What are the official names of this protein?
Probable auxin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the germin family.
Protein: UL29_HCMVA
Sequence: MSGRRKGCSAATASSSSSSPPSRLPPLPGHARRPRRKRCLVPEVFCTRDLADLCVRRDYEGLRRYLRRFEGSCVSLGWPSQCIYVVGGEHSPHSLTEIDLEHCQNDFFGEFRALHLIGTVSHATCRYQVFVDAYGAVFAYDAQEDCLYELASDLAGFFAKGMIRCDPVHESICARLQPNVPLVHPDHRAELCRRSRASARGRYLRSLLAFRELLACEDTAARCAYVEAHREAQLTLIWPEKHSLVLRTARDLGLSASMLRRFQRSLYTREPVMPLGEIEGAEDKTFFHRVRILCGDTGTVYAALVGQDKLVRLARDLRGFVRVGLALLIDDFRYESIGPVDRSSLYEANPELRLPFKKRR
What are the official names of this protein?
Uncharacterized protein UL29.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: NUOC_ACIC1
Sequence: MTEPVLRGLPSSPRPFGGYFDQVADTLAVAYPRLPDAIERTDVDRGELTFHVRREYLRELALVLRDDERLRFELLNSLSGVHYPTDVGRELHVVYELTSMTYRRHIRLEVAAPDADPHIPSVVDVWPTADFQERETWDMFGVIFDGHPALTRILMPDDWPGHPQRKDYPLGGIPVEYKGATVPPPDERRQYA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GHRB_YERPG
Sequence: MKPSIVLYKSIPTDLHQRLAQHFTVNSFDGLTPDNQPELLAALQQAEGLIGSGGKIDQDFLQLAPNLRAASTISVGYDNFDVEALSQRGIALMHTPTVLTETVADTMMALMLSTARRVVELAERVKAGEWQESIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPHEAAEQRFGARHCSLDTLLAEADFLCITLPMTEQTYHMIGREQLAKMKSSAILINAGRGPVVDEQALIAALQDGTIHAAGLDVFEQEPLPVDSPLLTLRNVVAVPHIGSATHETRYNMAACAVDNLINALTGTVKENCVNPQVLITH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_MESH2
Sequence: MQKPVPKKRLGQNFLKDRKIAEKIVENIDLKNKEIIEIGCGTGFLTNFLLEKAKFVTCYEIDKNLIPILEKKFKNKNLRIINEDFLLAEFESKEKKTIIANLPYYITSKILFKIFANFEKFDKIILMVQNEVADRIVAKPKTPTYSKLSLASQYIAKVRKLFVVGPDSFFPKPKVNSAVVSFDFRANLDAKEMENFFWFTKRCFQFKRKTLYNNLIFFLNKQQIEKIYNFFQFAQNIRPQQLDLVTYIRLADFYFNNIF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_DEIGD
Sequence: MTSVCFLAGRTAALIPAAGSGTRLGRGPKAFVEVAGQSLLARSVAALAPWVDEVLVALPEGFPLPPGLPAQAILGGTTRQESVWRLLHATTADVVLVHDAARPFLPGAVVTALLEAVSETGAATAALPVADTLVRGERGRWADLVPREGLWAVQTPQAFRRALLLRAHAAARAEGFGATDDAGLIARLGLPVRLVPGDARLFKVTTPGDLALAQAVAAVWDATCDAP
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TRPD_CHLSY
Sequence: MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAAVMREKATHVYFDGPVIDTCGTGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGSADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMRFAGPVRREIGIRTVFNILGPLTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRAGQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAMVAGDLAPDLATGVAMARHSIDSGRALERLNQMIAVSRGE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: AYT1_YEAST
Sequence: MFRVKIISQKRTKSVQMLENDQLDILGQQPSLYKLYTQICSIYRVPDPSAHDHIVNTLTRGLETLAKNFQWLAGNVVNEGADEGNTGTYRIVPSDKIPLIVQDLREDLSAPTMDSLEKADFPIYMLDEKTFAPCMTINPPGNTIGMAAKSGPVFAVQANFISGGLVLTIVGQHNIMDITGQESIINLLNKSCHQKPFSDEELLIGNIDKSKSIPLFDETWEPDTTLVHEIVETSRNTSGEEKEQSCSSNSTWAYVEFSAISLQNLRILAMQTCTSGTKFVSTDDIVTAFIWKSVSRARLSRLKPETKSNLGRAVDVRKRLGLPETYPGLLVNMTFNTGSLKSLDHKSLGVLASQIRRKLDPKVFDLAYNTCALATLLSRCPDKTKVSIPQPIDTLSGIMVSSWAKVSLYDVDFNLGLGKPKSVRRPRFISLESLIYFMPRSSRGEMVVALCLRDKDWECLNADKEWTNYATHIG
What is the function of this protein?
Trichothecene 3-O-acetyltransferase involved in self-protection against trichothecenes, mycotoxins acting as eukaryotic protein synthesis inhibitors.  Its existence is surprising in a non-trichothecene producer organism which needs no self-protection again endogenic trichothecenes.  The persistence of this non-essential gene may be due to a selective advantage that it may confer, like a resistance to exogenic trichothecenes.
What are the official names of this protein?
Trichothecene 3-O-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the trichothecene 3-O-acetyltransferase family.
Protein: KDUI_XANAC
Sequence: MSLYCKTHYATHPDAIKGASNDDLRELYLLDGLFVDDAVTLKYTHYERFVLGGAAPLGRTLELPRQTEPASAAGHPFLERRELGILNVGAGTGTVIVDGTAYTLGPKDGLYVAMGSTDVSFASEDAGNPAKFYLASTPAHARFETKQLSIKDAVALERGALETSNERTIYQYIVPATCQSSQLLLGLTVLKPGSVWNTMPPHLHDRRSEVYFYFDLGADDRVYHFMGEPDAQRHIVIQNNEAVVSPPWSIHMGAGTSNYAFIWAMGGENLDYTDMHVLDICQLK
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RECA_LACPL
Sequence: MADARKAALDTALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVAPPFKRAEVDIMYGQGISQTGEIVDMAAEKDIVKKSGSWYSYGDDRIGQGRENAKKYLDEHPDVMTEIRQKVRDAYGMDATGEETSETDDQAKEAKDKGTAKNGSKGQSKSTKATPAETALDLGDQPTEK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4E_HUMAN
Sequence: MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (PubMed:16271312, PubMed:22578813).  In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm (PubMed:24335285).  Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap (By similarity).  Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity).  In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (PubMed:24335285).  May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
Protein: SARA_STRGC
Sequence: MKKGKILALAGVALLATGVLAACSNSTSNSSNSSSSGADQVFNYIYEVDPENLNYLISSKAATTDLTANLIDGLLENDNYGNLVPSMAEDWTVSKDGLTYTYTLRKDAKWYTSDGEEYADVKAQDFVAGLKYAADNKSETLYLVQSSIKGLDDYVNGKTKDFSSVGVKAVDDHTVQYTLNEPESFWNSKTTMGILYPVNEEFLKSKGDKFAQSADPTSLLYNGPFLLKSITSKSSIEFAKNPNYWDKDNVHVSDVKLTYFDGQDQGKPAEQFAKGALSAARLAPTSATFSKVEKEFKDNIVYTPQDSTSYLVGVNIDRQAYNHTAKSSDAQKSSTKKALMNKDFRQALSFAFDRTAYASQVNGKEGATKMLRNLYIPPTFVQADGKSFGELVKEKVASYGDEWKDVNFDDAQDGLYNKEKAKAEFAKAKKALQEEGVEFPIHLDMPVDQTATAKVQRVQSLKQSIESSLGTDNVVVDIHQMKTDDVLNITYYAASAAEEDWDISDNVGWSPDYQDPSTYLEIIKPGGENTKTFLGFDGKENAAAEQVGLKEYAKLVDEAAAEKTDVNKRYEKYATAQAWLTDSALLIPTTSRTGRPVLTKIVPFTAPFAWSGAKGRDMASYKYLKLQDKAVTAKEYQKAQEKWNKERAESNKKAQEELEKHVK
What is the function of this protein?
May be involved in the expression of cell surface properties important for colonization of the human oral cavity.  It may also be involved in uptake processes.
What are the official names of this protein?
Oligopeptide-binding protein SarA, 76 kDa cell surface lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: UBID_SHEPW
Sequence: MSFKDLRSFIEHLESNGELKRISHPVDPHLEMTEIADRVLRSKGPALLFENPVGNDMPVLANLFGTPKRVAMALGKEDPLALRDVGELLAFLKEPEPPRGFKDAISKIPMFKQALNMPPKTVRNPPCQEVVKTAEEVDLTKLPIQHCWPGDVAPLVTWGLTITKGPRQKRQNLGIYRQQLLGKDKLIMRWLDHRGGALDFKDFKEKHPGDRYPVVVALGSDPVTILGAVTPVPDSMSEYAFAGLLRGERTEVCKAISCDLEVPATSEIILEGYIDPEEMAEEGPYGDHTGYYNETDSFPVFTVTHITHRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIIDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVVVDEDVNCRDWNDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGMDATNKWEGETDREWGTPIVMDEAVKQKVDEIWSDLGIDDAPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NC2B_MOUSE
Sequence: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASTQAGSSQDEEDDDDI
What is the function of this protein?
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes.  This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP.  Can bind to DNA on its own.  Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
What are the official names of this protein?
Protein Dr1, Down-regulator of transcription 1, Negative cofactor 2-beta, NC2-beta, TATA-binding protein-associated phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the NC2 beta/DR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIL2_ARATH
Sequence: MDSSLDGAAGDSSKCSEMSVDEKRQLVYELSKQSHLAAEVLQAWSRQEILQILCAEMGKERKYTGLTKVKIIETLLKIVSEKNSGECEGKKRDSDCLPIQRNTKRQRKVDNPSRYVIPATNIVTSNNASGSCSSVNTKGESTTIYCKNLACRAVLRQEDSFCRRCSCCICRKYDDNKDPSLWLTCSSDPPFEGESCGFSCHLECAFNTEKSGLGKDKQSEGCCFYCVSCGKANSLLECWKKQLTIAKETRRVEVLCYRLFLVQKLLKSSTKYRNLCEVVDEAVKTLEADVGPLTGLPMKMGRGIVNRLHSGPDVQKLCSSALESLETIATTPPDVAALPSPRSSKMQQDCSYVLSNEISADTATTGSTKIRFEDVNATSLTVVLASNEIPSPPNIVHYSIWHRKVPEKDYPEKSTCTLFIPNTRFVVSGLAPASEYCFKVVSYSGTREMGVDEINVLTRSAEEGANCSSAVERSVSPLTNCSTLSSNPSSVEAESNNDYIVPKKPSSKNEDNNSPSVDESAAKRMKRTTDSDIVQIEKDVEQIVLLDDEEQEAVLDKTESETPVVVTTKSLVGNRNSSDASLPITPFRSDEIKNRQARIEISMKDNCNNGDHSANGGTESGLEHCVKIIRQLECSGHIDKNFRQKFLTWYSLRATSQEIRVVKIFIDTFIDDPMALAEQLIDTFDDRVSIKRSAVGGSGASAVVPSGFCMKLWH
What is the function of this protein?
Maybe involved in both the vernalization and photoperiod pathways by regulating gene expression.  Binds preferentially to dimethylated histone H3 'Lys-9' (H3K9me2).  Promotes flowering in non-inductive photoperiods (e. g.  short days) through the maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)-dependent H3K27me3.
What are the official names of this protein?
VIN3-like protein 2, Vernalization5/VIN3-like protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Probably DNA- associated.
Protein: Y3910_BRUSU
Sequence: MTEITDRYFNDVIARLSGLRDRLAAQMEKAADLIAAAARADRRVYVFGTGHSHMMAEELHYRAGGLAITVPILCGSIMLQDGAVASSHFERIEGAVRPILDRYGIRDGDVLVVVSNSGVNAAPIEAARYAREKGAAIIALTSVAYSNTIARGRTQLLSLADVVLDNDAPSGDAVLEIAGSALKVGPVSTALGVTILNAVFADVAARLVGEGDAPIYLSANMPGSGDINRSLVERYRDRNPHL
What are the official names of this protein?
UPF0309 protein BRA0910/BS1330_II0902.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.