PharMolix/UniProtQA huggingface dataset:
Protein: HEM6_NITEU
Sequence: MNFAQVKDYLVDLQNRIVTGLEQVDGQSFRRDTWDRPEGGGGTSCVIEEGNVLERGGVNFSHVFGKGLPASATAARPELAGRAFEAAGVSLVLHPRNPYAPTVHMNVRFFAATKEGAEPVWWFGGGMDLTPYYGFEEDAVHFHQACKDALQPSGEEYYPRFKKWCDEYFYLKHRKEPRGIGGVFFDDLNQPDFATCFNLTRSVGDHFLAAYVPILQKRRDLPYGERERDFQAYRRGRYVEFNLVWDRGTLFGLQSGGRTESILMSLPPVVKWRYDWSPAAGSPEAKLYTDFLTGRDWLPLG
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_GEODF
Sequence: MQISVESLSSVKKKINFEIPAARVASEVEKVYDEIRKHAAIKGFRKGKVPKDIIKKHYHEKMADDVLKNIVNDTYFKALTDEKIYPVSYPVIDSDELKVGENFKYSATVEVFPDVEVKDYDGLEVKKEKFVLNDEVVTGRLREMQENMAHLEPAEAGVAAKSGDYVTFDFKGSIDGVPFDGGAADDFQLELGSGRFIPGFEDQLVGMKSGDESEIKVTFPENYGQKDLAGKDASFTVKIKEIKVKELPELNDDFAKDFGEFETLEDLKKKIAEVHNLQENERIEADLRDRLIKALIEKNSFEVPETLVDKQLNLMLENSKRRLAMQRLTIEMMGLNDEGYKAQFRSAAETQVKGSILLDALARKESIEVTAAEVDEKLEQIAQQNNQDLEQVNKFYQQNAQAKENLSAQLKEDKAIELLLSKATVTEVERKELDK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS2_LEPIN
Sequence: MSVISMKNLLETGVHFGHQTRKWNPKMAPYVFTARNGIHIIDLQKTVQKAKEAYDALKKLTSEGKKVLFVGTKKQARGAIEREAIRSNMFFINNRWPGGLLTNWNTVKRSIARLKKLEGMEADNSFEKEVKTKKEVLTLRRELEKLRKTLGGIKDMATIPEIMFVIDPKKEEIAVKEARKLGLKIFAVVDTNCDPELIDYPIPGNDDAIRAISLFLETMSNAVIEGTGGVVEQPRFSEDLDSEALALEYQGEYDESGKFIMDEDPDSKKTKTAEEPSATIEPSTTTTVEVDQNE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: EFG_XANCP
Sequence: MARTTPIERYRNFGIMAHIDAGKTTTSERILFYTGVSHKIGEVHDGAAVMDWMEQEQERGITITSAATTAFWTGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYSVPRMAFVNKMDRTGANFDKVVEQLKARLGAYAVPMQVPIGAEDGFEGVVDLLKMKAIHWDTASQGTTFEYRDIPADLVDVATEARSFMVEAAAEASEALMDKYLNDGDLSEDEILSGLRERTLKVEIVPVFCGSAFKNKGVQAMLDGVVHLLPSPADRPPVQGIDENEKEDTRDATDTAPFSALAFKIMTDPFVGSLTFFRVYSGTLNSGDQVYNPVKSKKERVGRILQMHSNNREEIKEVRAGDIAAAVGLKDVTTGDTLCAQDKIITLERMVFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHAKQSGGKGQYGHVVIELSPMTEEDRKNDSVKDDFLFINDITGGIIPKEFIPSVEKGLRETITSGPIAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKASPVLLEPIMKVEIVSPEDYLGDVMGDVSRRRGVLQGQDDSPSGKIINAMIPLGEMFGYATSLRSMSQGRATFSMEFDHYEEAPANIADAVTKKG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_CAMJR
Sequence: MLEGIVRESIGRKAAKALKRDGYLIANIYGKGLENINAAFKVNEFIKEVRKKTTLIFDVKVGSQTLSVVVVDYQKDPVTAELKHVDLKVAQKGVISKYMVPVKITGTAIGLKNKGVLIQSKRRLKVKCAAENLPNFFELDVSKLDVGDALLVRDIVVPAGVTMIDADRVAVVGVEKAR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: MUKB_PHOLL
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVINSRHQRVVVGVRLQQVAGRDRKVDIKPFMIQGLPTAMQPTQLLTENVGERQARVLPLNELKDRLDEMEGVQFKQFNSITDYHALMFDLGVIPKRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRITLEAIRVTQSDRDLFKHLITEATAYVSADYMRHANERRTYLDQALALRGELFGSHRQLATERYRHVEMARELEEQSGASVDLEADHQAASDHLNLVQTAMRQQEKIDRYQGDLEELSYRLEEQTEVVEEAAELQAEYEARAEAAEQEVDELKSQLADYQQALDVQQTRAIQYQQALQALERARELCRLPDLAADNAEAWLETFQAKEQQATESLLTLEQKLSVADAAHSQFERAYQLVKNMVGEISRSEAWQSARELLRDWPSQQHLADRVQPLRMRLAELEQRLTNQQNAEFLLNEFCKRQGQQYQAEDLEGLQSELEARQEALSLSVNESGERRMEMRQALEQLKQKIQSLTARAPVWLAAQDTLSQLCEQNGEALASSNDVTEYMQQLLEREREATVERDEVAAQKRELEKQIERLSQPSGAEDSRMIALAERFGGVLLSEIYDDITIDDAPYFSALYGPARHGIVVPDLSLVRSHLETLEDCPEDLYLIEGDPQSFDDSVFNAEEQANAVLVKSSDRQWRYSRYPELPLFGRAARENRLEALNLERDTLAERYATLSFDVQKIQRAHQAFSQFVGKHLSVAFDTDPEAEIRELRQRHTELERELSRFEEQTQQQRQQYTQAKESLTTLNRLIPQVTLLLDETLIDRVEEIREELDEAQEAARFLQQHGSALAKLEPMVAVLQSDPQQHEQLQQDYETAKQSQHQAKQQAFALVEVVQRRAHFSYSDSAGMLSENADLNDKLRQRLEHAESDRSRAREQLRQQQAQYSQFNQVLASLKSSYETKQDMLKELHQEMKEIGVRADANAEMRARERRDQLHEALSANRSRVNQLEKQIAFCEAEMDSLQKKLRKLERDYYQIREQVVSAKAGWCAVMRMVKDNGVERRLHRRELAYMEGGALRSMSDKALGALRLAVSDNEHLRDALRLSEDPKRPERKIQFFIAVYQHLRERIRQDIIRTDDPVDAIEQMEIELARLTEELTAREQKLAISSKSVANIIRKTIQREQNRIRMLNQGLQAVSFGQVRGVRLNVNVRESHALLLDVLSEQQEQHQDLFNSQRLTFSEAMAKLYQRLNPQVDMGQRLPQTIGEELLDYRNYLELDVEVNRGSDGWLKAESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFKNHEHVHVVGLRGFGQDVPATQLISDATA
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RL22_BIFLD
Sequence: MEAKAIARHVRVTPRKARRMVDLIRGKKATEAVTILKFAPQAAALPVRKTLESAIANARVKADKAGEPFRENDLYIKETYVDEGVTLKRFRARAQGRAARINKRTSHITVVVANKEGAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TFDF2_CUPPJ
Sequence: MTGDLNEFVAHFWPVRVVFGAGSTERIPAEVKRLGARRALVLCTPDQRDLAQRVLGDLGDLGAGFHDGAVMHVPEASVTRAAQAARDADADLLVAVGGGSTIGLAKALALHHGMRFVALPTTYAGSEMTPIWGLTADGAKRTGRDPRVLPSTVLYDPHHLTSLPPEVTGPSGMNAIAHAVESMYAPDRNPITMLLAEESIRAMAQGLPVAVDSPGDLDARTRTLYAAWLAGTVLGMVSMGLHHKLCHVLGGRFNLPHAPMHAVLLPHVAAFNEVAAPAELGRVAAALGAPGPGGAGAALHALLRFTCTERSLAAIGMPAQGIYDAAEHALADAYANPRQASREDIARLLRAAFTGEMPA
What is the function of this protein?
Plays a major role in the degradation of chloroaromatic compounds by channeling maleylacetate and some of its substituted derivatives into the 3-oxoadipate pathway.  This enzyme converts maleylacetate and 2-chloromaleylacetate with similar efficiencies.  NADH is preferred to NADPH as the cosubstrate.
What are the official names of this protein?
Maleylacetate reductase 2, Chloromaleylacetate reductase, Maleylacetate reductase II.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: SIP5_SCLS1
Sequence: MGHQQSSMNPSRGDSHGDRHRHYDAGVSGPTSASDQDPYASRNGRGGRRNLVAAIVGGGSNNEVPERKETAAERQLRRLERERIARIEERERSIKEEHVDGGYLVTMGVYTGPEDFNKAIVRQLMIERRVAPFWRGLDDYQDDWTEHQLVAAGRGLPIPAADEVPAEDIAGPHSPDSANVSSSNLQNLMVPLASRTQSASYDTSLSLSPSHPAFSTPSSVPPLNAPTTSTSLLRPRSKTLGLRSSAKEPPAPDPAPREIQLPRDTQVNGQAIEAFLYKDAVECSICLIWYPPYLNRTRCCDQSICSECFVQIKRPEPHTPEHHGPPPIASENAEDTEMLVSEPAACPYCQRPEFGVTYEPPPFRRGLVYAKPSPEVANFSSAMSSSSSINSPPLTSSGLAAPRGDRRRATSLSANDSHVITTDRIRPDWSAKLEAANLRKAKKNAAASALHAAAFVLPGTSENRTYTFGRSRFGRNNRSDNSAEASGTATPPNRDASSRAVIESSGHARREDQDPNATRRMRRDDLEELMMAEAIRLSIAAEEERKKKANKEAAKEAVKQAKKQAKEDKKKEKKERKSIYGANGNSASSSMLNLGSSIAATFTGRRRGDSTASHLAIEVTPEEVEVPVQGKGKGVDRPSLANQGSSTDNGLPSGQHSDPSTSSSLLETHQSVTSPASPDKLSHIREMSTVSSAASSLVESGNGTNAQGSSTSIENPGTNGASSEGNEDGDSGTESMFNFQSLTALIEKEDDNEKTHSADHVENAHEASDSRHGSRDENASQDMDVSMETIRPADSPARVDNIDRNHSSTTGLQMLDTEIDTSIITPQLTITPETPAVMNPTEENGKQLGSSFTSRTNAEITQ
What is the function of this protein?
May negatively regulate the snf1 kinase.
What are the official names of this protein?
Protein sip5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDFD_ECOLI
Sequence: MNSAFVLVLTVFLVSGEPVDIAVSVHRTMQECMTAATEQKIPGNCYPVDKVIHQDNIEIPAGL
What are the official names of this protein?
Uncharacterized protein YdfD.
Protein: Y093_MYCS2
Sequence: MRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRDEFAFLLVSAAGPTWAQMAVSDPHWLGADADARRIHEISRNYQAVRTHYFDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLEYKTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGLLPYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGEQMRKQLDLDIDVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMARLGRPAAEADLAEFGMDGVLMRARLDGERL
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MSMEG_0093.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: SYGA_HELPJ
Sequence: MQDFSSLLLKLQEYWKDQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCSPIPVEITYGLERLTMYVQKVENILEIEWAKKDNESVRYAQVHLESEYEFSKYHFEVASVERLLEMFKNAQAEALHCLENKLPLPAYDLVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCAVLYKEQEEEREERLKNALTKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_CLAM3
Sequence: MAQDVLTDLNKVRNIGIMAHIDAGKTTTTERILYYTGITHKIGEVHDGAATMDWMAQEQERGITITSAATTCFWNKNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSETVWRQADKYDVPRICFVNKMDKLGADFYFTVDTIINRLGAKPLVIQLPIGSEGGFEGVIDLVEMRALTWRGDSKGDVELGAKYDIEEIPADLQDKADEYRAKLLETVAETDDSLLEKYFGGEELTVAEIKAAIRKLTVNSEIYPVLCGSAFKNRGVQPMLDAVIDYLPSPLDVPPMEGHDVRDEEKIIIRKPDSTEPFSALAFKVAVHPFFGRLTYVRVYSGTIASGSQVINSTKGKKERIGKIFQMHSNKENPVDSVTAGHIYAVIGLKDTTTGDTLCDPQDQIVLESMTFPEPVIEVAIEPKTKADQEKLGVAIQKLAEEDPTFRTEQNQETGQTVIKGMGELHLDILVDRMKREFNVEANVGKPQVAYRETIRGTVDKHDFTHKKQTGGSGQFAKIQIKIEPMEVTAEKTYEFDNKVTGGRVPREYIPSVDAGIQDALQVGILAGYPMVGVKATLLDGAAHDVDSSEMAFKIAGSMAFKEAARKAKPVLLEPLMAVEVRTPEEYMGDVIGDLNSRRGQIQAMEDASGVKVITANVPLSEMFGYVGDLRSKTSGRAVYSMSFGSYAEVPKAVADEIVQKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_CLOBA
Sequence: MKIAIDGMGGDNAPSAVVEGVVSALKEYSEMTFYITGPEDKISLELSKYDYPKDKIIIIDAKEVISTNEHPVMALRRKKDSSIVKALNLVKDAHCDGIISAGSTGAFLAGCTLIVGRIKGVERPALGPIMPGRRGNFMIVDAGANVDSKPEYLVQFSKMGSIYYKNVFNVDIPSVGLLNIGAEEEKGNDLTKATYKLLKEENSINFVGNIEPRYIPTGDTNIIVSDGFAGNTALKMYEGSAKNILGMIKDEVLKADLKSKIGVLLLKPFLKRIMKKFDYKEYGGAPFLGVNGICIKAHGSSDGKAFKNAIRQTKIFYENNVLDEIKKEFEKKN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FLUB_ASPFN
Sequence: MGRWICMYHTVPHARPSLADRRVFRIQPVTQFLATTTTFQHRASSEASYVPLEPGLLLLCCFYPIGNLILLVRLSLVLRNGSLVLPLSCV
What is the function of this protein?
Cluster 41 protein; part of the gene cluster 41 that mediates the biosynthesis of an extracellular and diffusible metabolite that is able to stimulate colony sclerotial production (PubMed:27647242).
What are the official names of this protein?
Cluster 41 protein AFLA_114800.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y355_CHLTR
Sequence: MRVVERAVIACYLGITIFSGIAFGYEGAFSSGSFEQNPSGVAIHNRVLFKVDEDTVVTTLDVIRKLNILFYSTCPQLVDSVSARSQYYSAMWPVVLETVINEFLMAADAKAKKIFIDPTSVNQEIEAMFGRDLSPFAKFFDMTPEDVFNVVHRILVAQRVEGMMVRSRVMLKVTPGMVREYYQKLADEAAQITQWTYRVLTIKAGLEFLAHKIAGKVQERLNEGSSWDKERLTALVLSQGGQLMCSEEFFREDAQLSVAHRQSLEEINFPEERCGKVLEHASGLKLFVLFNRATKTLDPLDKMEAQLKQQLMMEFAAEEEANYKNKLHARYGFDPATITKLLAEDAPQLFSLL
What are the official names of this protein?
Uncharacterized protein CT_355.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_1058/CT_355/TC_0634 family.
Protein: YKJ2_CAEEL
Sequence: MSKYLRTSHPSPLICRPILTFSSLHILTAFLISGNSSYINWSVTIILLILGLYACHRFLNMKKLTRDAQEPLLPHIRPSTRNKIRKYIYGTIFILSIFLLYRSLNSPDTSKHGIGRNGDFIEYEPKAGPTIKEPVENIVKLDVYMEAQCPDTSRFFRQQLKKAWDILGRLNRIELNVIPFGKARCTEKGNDFECQCQHGPTECQINQLMNCVIDRFGFPHRYLPGVLCMQGKYSLDEAMKCVTENYPSEYERMRECASGTRGRRLLALSGQKTASLTPAIDFIPWIVINGSRNSDALYDLTQNVCEAMQPMPSACKDYLRSLQ
What are the official names of this protein?
GILT-like protein C02D5.2.
What is the protein family that this protein belongs to?
Belongs to the GILT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FMT_BIFAA
Sequence: MLKVLFAGTPDVAVPSLKLLAQDTEHFEVVAVLTRPDAPTGRGRKLVANPVKQAALELGLPVIESDPSEETFVSELAATGAQAAAVVAYGKILKQDVLDALPMGWYNLHFSLLPQWRGAAPVQRSIWAGEKVTGATVFRIVRAMDAGPILAQSTVEIGAHETAGELLGRLAEDGSHLLAASLQALADDQIAPVEQPAGAYEVAQKITVEDAHIRFDVPVFAADRQIRACTPNPGAWCELHAHADAEPATLHVLRAQPADMSNPNAPASLEPGHIVAGKKNVWVGTSTEPLELLEVKAQGKKAMRAADWARGAHLDNAFCE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TYSY_GEOKA
Sequence: MRQYLQLLEDILENGVEKEDRTGVGTLSVFGRQLRFNLQDGFPLVTTKKLHIRSIIYELLWFLKGDTNVRYLQENGVTIWDEWADENGDLGPIYGAQWRSWKGADGKTIDQIAWVVEEIKRNPNSRRLLVSAWNVAELDEMKLPPCHYAFQFYVANGRLSCMWQQRSVDTFLGLPFNIASYALLTHMIAQQCDLDVGELIFTGGDVHLYKNHLEQAKLQLTREPRPLPKLVIKRKPPSIFDYEYDDFEIVGYNPHPTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_SYNWW
Sequence: MTLDERKRNILGSIIRDYVETAEPVGSRAMVKKHDLKISAATVRNEMADLEDMGYLEQPHTSAGRIPSERGFRYYVDCMMEKEPPGEREYALLQQLFEQNIEDWEQVILGIAHFLSQMTRYTSFVIVPAVKFTEFRNLQLLPLDQGKALLLLVCDMGVIMHRIISIPEFISSQDLQAITGLFNQAFIGKRLEEVKRSDLQLIRENLSQRRQIIDNALEAIDNLLQNSRDEKVMVSGALNILNEPEFKDMDKLKRILNVLEEDDSLRQIIPGELGEAVDIKIGRENPLEEIKEMSLVVAGYKSFGELGKIGVIGPVRMEYWKAVGTVETVRDIIEDYLKGLG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GCSH_MICAN
Sequence: MELEYPEDLRYLETHEYVRLEGEIATLGISAFAVDQLGDIVFLELPELGEALKVGSSFGTIESVKAVEDLYPPVSGTVVDRNQAMIDSPELIADDPHGEGWLLKVRVENPDTALADTLSASEYRTQVAGES
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SYP_BACAC
Sequence: MKQSMVFSPTLREVPADAEIKSHQLLLRAGFMRQNASGIYSFLPFGLKVLHKVERIVREEMERAGAVELLMPAMQAAELWQESGRWYSYGSELMRMKDRNAREFALGATHEEVITDLVRDEVKSYKKLPLTLYQIQTKFRDEQRPRFGLLRGREFLMKDAYSFHATQESLDEVYDRLYKAYSNIFARCGLNFRAVIADSGAMGGKDTHEFMVLSDVGEDTIAYSDTSDYAANIEMAPVVATYTKSDEAEKELEKVATPDQKAIEEVSAFLNIEADKCIKSMVFKVDEKLVVVLVRGDHEVNDVKVKNVYGASVVELASHEEVKELLNCEVGSLGPIGVNGDIEIIADHAVASIVNGCSGANEEGFHYVNVNPERDFKVSQYTDLRFIQEGDQSPDGNGTILFARGIEVGHVFKLGTRYSEAMNATFLDENGKTQPLIMGCYGIGVSRTVAAIAEQFNDENGLVWPKAVAPFHVHVIPVNMKSDAQREMGENIYNSLQEQGYEVLLDDRAERAGVKFADADLFGLPVRVTVGKKADEGIVEVKVRATGESEEVKVEELQTYIANILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATD_PONAB
Sequence: MSGKDRIEIFPSRMAQTIMKARLKGAQTGRNLLKKKSDALTLRFRQILKKIIETKMLMGEVMREAAFSLAEAKFTAGDFSTTVIQNVNKAQVKIRAKKDNVAGVTLPVFEHYHEGTDSYELTGLARGGEQLAKLKRNYAKAVELLVELASLQTSFVTLDEAIKITNRRVNAIEHVIIPRIERTLAYIITELDEREREEFYRLKKIQEKKKILKEKSEKDLEQRRAAGEVLEPANLLAEEKDEDLLFE
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit D, V-ATPase subunit D, Vacuolar proton pump subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin- coated vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Note=Localizes to centrosome and the base of the cilium.
Protein: PUR9_BRUO2
Sequence: MAVSSKHIPAPDLHRVRRALLSVSDKTGLIDFAKALHANGVEILSTGGTAKSIAAAGIPVKDVSEITGFPEIMDGRVKTLHPAVHGGLLAVRNDPEHVAAIEEHGIGGIDLAVINLYPFEEVRFKGGDYDTTVENIDIGGPAMIRASAKNHAYVATVVDPADYADVVAELEKHSGSLPLAFRKKLAAKAFSRTAAYDAAISNWFAEAIDEETPTYRAVAGKLHSVMRYGENPHQTAGFYLTGEKRPGVATATQLQGKQLSYNNINDTDAAFELVAEFDPARTAAVAIIKHANPCGVAEASTIKEAYLKALACDPVSAFGGIVALNRTLDEEAAEEIVKTFTEVIIAPDATEGAQAIVAAKKNLRLLVTGGLPDPRAKGIAAKTVAGGLLVQSRDNGVVDDLDLKVVTKRAPTEAELNDLKFAFRVGKHVKSNAIVYVKDGATVGIGAGQMSRVDSARIAARKAEDAAEAAGLAAPLTKGCVVASDAFFPFADGLLSAVEAGATAVIQPGGSMRDDEVIAAADEHGIAMVMTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PHOE_ENTCL
Sequence: MKKSTLALVVMGVVASASVHAAEVYNKNGNKLDVYGKVKAMHYISDDDTKDGDQTYVRFGFKGETQINDQLTGYGRWEAEFAGNKAESDSSQKTRLAFAGLKLKDFGSLDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGAIDGLDMTLQYQGKNENRDAKKQNGDGFGTSLTYDFGGTDFAVSGAYTNSDRTNAQNLLARAQGQKAEAWATGLKYDANDIYLAAMYSETRNMTPISGGFANKAQNFEVVAQYQFDFGLRPSLGYVQSKGKDNEGIGDEDLVKYIDVGATYYFNKNMSAFVDYKINQIDDDNKLGVSSDDIVAVGMTYQF
What is the function of this protein?
Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes.
What are the official names of this protein?
Outer membrane porin PhoE, Outer membrane pore protein E.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL21_PARXL
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIKFGTPLVSGASVKATVVSQGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RSMH_ECO27
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLASGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.