PharMolix/UniProtQA huggingface dataset:
Protein: GCSAM_HUMAN
Sequence: MGNSLLRENRRQQNTQEMPWNVRMQSPKQRTSRCWDHHIAEGCFCLPWKKILIFEKRQDSQNENERMSSTPIQDNVDQTYSEELCYTLINHRVLCTRPSGNSAEEYYENVPCKAERPRESLGGTETEYSLLHMPSTDPRHARSPEDEYELLMPHRISSHFLQQPRPLMAPSETQFSHL
What is the function of this protein?
Involved in the negative regulation of lymphocyte motility.  It mediates the migration-inhibitory effects of IL6.  Serves as a positive regulator of the RhoA signaling pathway.  Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK.  Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
What are the official names of this protein?
Germinal center-associated signaling and motility protein, Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated lymphoma protein, hGAL.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
Protein: Y1168_STRA3
Sequence: MYHIELKKEALLPRERLVDLGADRLSNQELLAILLRTGIKEKPVLEISTQILENISSLADFGQLSLQELQSIKGIGQVKSVEIKAMLELAKRIHKAEYDRKEQILSSEQLARKMMLELGDKKQEHLVAIYMDTQNRIIEQRTIFIGTVRRSVAEPREILHYACKNMATSLIIIHNHPSGSPNPSESDLSFTKKIKRSCDHLGIVCLDHIIVGKNKYYSFREEADIL
What are the official names of this protein?
UPF0758 protein gbs1168.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: APAG_ECO5E
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: MPRAB_DANRE
Sequence: MATVVMEQIGRLFINAQQLRQIPRFLESAFPKLPCTVMVSDVPWVFRESHIITGYRPPDQNWRYYFLTLFQRHNESVNVWTHLLASLIILVKFQELSETVDFLRDPHAQPMFILLLAAFTYLGCSALAHLLSAKSEISHYTFYFLDYVGVAVYQYGSALAHFYYVVEEEWHAQVRTFFLPASAFLAWLSCTGCCYGKYASPKLPKFVHKLFQVVPSGLAYCLDISPVLHRIYRCYSSEHWCADQAVVYHCYQVLFFLISAYFFSYPHPERWFPGRCDFIGQGHQIFHVFLVLCTLVQIEAVRLDYTERRRLYEHLHGDLAHDAVALFIFTACCSALTAFYVRKRVKTYLEEKQE
What is the function of this protein?
Steroid membrane receptor.  Signals upon progestin binding, resulting in rapid activation of MAPK and down-regulation of adenylyl cyclase activity.  Interacts with steroids with varying degrees of affinity, showing specificity for activation by the maturation-inducing steroid (MIS) 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP).  Capable of mediating progestin-induced oocyte maturation.
What are the official names of this protein?
Membrane progestin receptor alpha-B, mPR alpha, Progestin and adipoQ receptor family member VII, b.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPP_PSYCK
Sequence: MSAHTTAQSAQYNQSATQAALVPMVVEQSARGERSFDIFSRLLRERVIFLTGQVEDHMANLIVAQLLFLEAENPDKDIHLYINSPGGSVSAGLAIFDTMNFIKPEVSTICMGGAYSMGSFLLAAGEKGKRYALANARVMIHQPSGGAQGQATDIEINAREILKTRARLNEILAERTGQPVDKIEKDVERDYWLDAKEAKEYGLIDEVLERRPASL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_SYNS3
Sequence: MPEANTFSDAGPDLWQCLGWQPNENQLSQLKELQALLRHWNSRVNLTRLVENEEFWIAQVFDSLWPLEKELRTPDLTRRCIDVGTGGGFPGLAVAIALPGTSLTLVDSVGRKTAAVESMANALGLGTRVDVRTERVEVTGQKRSCRGTFDLAMARAVATPPVVAEYLVPLLAHQGQALLYRGHWSNDDEANLKRALVPLKAKLADCKQINLPAGRGLRTLIRIESIAPCPKSYPRPVGLPNRLPLGNQADDKRS
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_DUVV
Sequence: MDAERIVFKVRNQLVSVKPEVISDQYEYKYPAITDKKKPSITLGRAPDLKTAYKSILSGMNAAKLDPDDVCSYLAGAMILFEGVCPEDWVSYGIHIARKGDKITPATLVDIVRTNTEGNWAQTGGQDLTRDPTISEHASLVGLLLCLYRLSKIVGQNTGNYKTNVADRMEQIFETAPFVKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRVDHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIKRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQIRSLNATVIQSCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQDYEEAEATKIEAALADDGTVNSDDEDFFSGDTRSPEAVYTRIMMNGGRLKGAHIRRYVSVSSSHQARPNSFAEFLNKTYSSDSR
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GSA1_BACCZ
Sequence: MKFTKSEALHKEALEHIVGGVNSPSRSFKAVGGGAPVAMERGKGAYFWDVDGNKYIDYLAAYGPIITGHAHPHITKAITTAAENGVLYGTPTALEVKFAKMLKEAMPALDKVRFVNSGTEAVMTTIRVARAYTGRTKIMKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPQSIAQEVITVPFNNIETLKEALDKWGHEVAAILVEPIVGNFGIVEPKPGFLEKVNELVHEAGALVIYDEVITAFRFMYGGAQDLLGVTPDLTALGKVIGGGLPIGAYGGKKEIMEQVAPLGPAYQAGTMAGNPASMASGIACLEVLQQEGLYEKLDELGAMLEKGILEQAAKHNIDITLNRLKGALTVYFTTNTIEDYDAAQDTDGEMFGKFFKLMLQEGVNLAPSKYEAWFLTTEHTKEDIEYTIEAVGRAFAALADNK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U2A2B_WHEAT
Sequence: MADDNGGGGDDYVSEAVRPEGDTHTREEGLSKSRDRDREKDKDKERHRDRDRDRGRDRDRGRDRDLDKDRDRDKDRDRHQRHHRDKREHRDRPDDHDRHRSRDSERRRDRERDGHRRHRSRSRSRSRGRDDHRSRSHSKSKRVSGFDLGPTAQSVLPQFPTIPTPSQLPGSSIPGMFPNMLPFADGQINPLVMQPQAMTQQATRHARRVYVGGLPPSANEQSVAIYFNQVMAAIGGNTAGPGDAVLNVYINHDKKFAFVEMRSVEEASNAMALDGILFEGAPVKVRRPTDYNPSLAAALGPSQPSSNLNLAAVGLTPGSAGGLEGPDRIFVGGLPYYFTEAQVRELLESFGPLRGFDLVKDRETGNSKGYAFCVYQDLNVTDIACAALNGIKMGDKTLTVRRANQGSAQPRPEQENILLQAQQQVQLQKLVYQVGALPTKVVCLTQVVTADELKDDEEYEDIMEDMRLEAGKYGNLVKVVIPRPHPSGEPVSGVGKVFLEYADVDGSTKAKTAMHGRKFGGNPVVAVFYPENKFADEDYDAAA
What is the function of this protein?
Necessary for the splicing of pre-mRNA.
What are the official names of this protein?
Splicing factor U2af large subunit B, U2 auxiliary factor 65 kDa subunit B, U2 small nuclear ribonucleoprotein auxiliary factor large subunit B, U2 snRNP auxiliary factor large subunit B.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F10C1_MOUSE
Sequence: MHGHGGYDSDFSDDEQGGGSSKKRKKTVEDELLLTKPFQKERHGKVAHKQVAADLLDREEARNRRFHLIAMDAYQRHTKFVNDYILYYGGKREDFKRLGENDKTDLDVIRENHRFLWNEEDEADMTWEKRLAKKYYDKLFKEYCIADLSRYKENKFGFRWRIEKEVISGKGQFFCGNKCCNEKEGLRSWEVNFGYTEHGEKRNALVKLRLCQECSFKLNFHHRRKEIKSTKKKSKTTPECDESPRKKSRSPPSEEASKGKDEGHSSSKKSEDSRNRNAEEEDSASDSELWKGPLPETDEKSQEEEFDDYFQDLFL
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Protein FRA10AC1 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_BORPE
Sequence: MPGIKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQERMRAGRPYATKVREIAAHLMQANPEYSHPYLVEREVKAVGVVLVTTDKGLCGGLNTNISRVTLSKLKEFEQRSIKVQATAFGNKGLGLLTRIGAKLVSQEVQLGDKPDLDRLLGAIKVQLDDYLEGRIDALYVATTRFVNTMKQEPVFLRLLPLSNGLDDPFQSGVETLAKTAEIKSDYSWDYIYEPDAKSVIDDLLQRYVEGLLYQAVAENMASEQSARMVAMKSASDNAKKVIGDLQLVYNKTRQAAITKEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIBA_TERTT
Sequence: MAIEYVESSKLPTAWGMFEMHGFTDSETDKEHLVLSMGDLAGDEPVLVRIHSECLTGDALFSLRCDCGAQLQAAMHRISIEGRGAIFYLRQEGRGIGLVNKIRAYHLQDKGADTVEANEALGFGADMRDYSMLKPMFEKMGISRVKLMTNNPRKIDALIGLGIDIAERLPHETGRNPHNSHYLETKRGKLGHLLEGDSE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: HACL3_ORYSJ
Sequence: MMAKTLQGTQQQYAASGFPTQQYPTSGWTQSAAEILQLDNMDQDTSVVRNIIHRKIVEYLNERKEFCNFDLSFLMEIGKCIDRHLFEKADSKIKYMDLETLRTRLNAIVNSASFRGSMFHWSASAASSKLNSQQLPVMEVPIYHDRVTPGPNNLPSCAYNVSSTQGYNQYENCMGAANFAHSLADKPKQMPERLANTIFTSCASTLPKCSPSIDVLHIGHIKEHFSGDAYQNDSSQPSTSGSSSSLSAVWDQTTCSSAMRTLPMDSFSTVNGQNLSTNNKSLYPTTGQGPLLQQYIECEMKQETWSRSLEQSDQSNITTGNRDLYHAQIHPYINGEHKRDRCIQMKEKLGHTSDHEGFSREKSSNLSNHFMHHQQGFMTNYGACSPVSKTVDRAEQTSNSTVSKPTSPASDGSSGKHYPAKRLKVDVPHLVHVNEMEASKEQQPAANETYASAETVQSEVTNSPTKSPCCTSLGDNIACTDNVHGMDMVRLSGSAVQTEEEFRRENSDIEMKDAKVDLLDQTLSGDSLRARKRRGASVLYALTSEELKDHLCTLNHDTSQSKVPTEELLSVEGLPDQNTCNLCGMERLLFEPPPRFCALCFKIINSTGSYYVEVENGNDKSSICGRCHHLSSAKAKYQKRFSYAETDAEAEWWVQCDKCKAWQHQICALFNPKIVDPEAEYTCAKCFLKEKDNEDVDSLEPSTILGARELPRTRLSDHIEQRLSERLVQERQQRAIASGKSVDEVPGVEGLTVRVVSSADRTLQVQPRFKDFFKKEQYPGEFPYKSKAILLFQKNEGVDVCLFAMYVQEYGSACPSPNQRHVYLAYIDSVKYFRPEIKSASGEALRTFVYHEILIGYLDFCKKRGFVSCSIWTCPSTKRDDYVLYCHPTIQKMPKSDKLRSWYQNLVKKAVKEGVVVERNTLYDFFLQPTNECKTNISAAWLPYCDNDFWPGEAERLLEKKDDDTSQKKETQLGRLLRVAKRDDRKGNLEDILLVHKLGERLRTMKEDFLMLCLQQFCKHCHHPIVSGSSWVCTSCKNFFLCERCYAEELNTPLKDRHPATTKQKHAFERIEEEPLPETDDVDPTMESKYFDSRIDFLKHCQDNQYQFDTLRRAKHSTMMILYHLHDSTCSSCHRAMDQCLAWRCLVCLGCNFCDSCYKQDGESLHIHKLRQKKDHHVLQKYTLQDYLEGLVHASRCFDRSCTSKLCLTLKKLFFHGVRCHTRARGGGGCHMCVFMWKLLFTHSLLCDNADCSAPRCRDIKAYIADRSMTDLSISG
What is the function of this protein?
Acetyltransferase enzyme.  Acetylates histones, giving a specific tag for transcriptional activation.
What are the official names of this protein?
Probable histone acetyltransferase HAC-like 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: CASG_RHOJR
Sequence: MTAPTDPQLHLDQVMSRLTGPGGRFELVEEPVLGTRMPVMKNRGRSVGELLTTSLRWGDRDYLVTADRRMSYTEHAAAVAALATALREDYGVRKGDRVAILAANTPEWVVAFWATQVLGAISVGLNGWWVPREVEYGLTHSRPTVVVADAKRAETLAAVGTDLPVLTMEEDLPALFARYAGSPMPHTDVDEDDPAAILYTSGTSGRPKGALHSQRNILAVVDYHRFSDAVVGEFSGRPVDPAVPSPLRYLLTSPLFHIASLHNLVIPRLATGGAVVMHQGGFDVDAVLRLVERERVTNWGAVPTMASRLVEHDDLDKYDLSSLTSFSLASAPSSVAFKERLREKVPFARNALVDSYGLTECSTAIAVATAPELEQFPGTLGRPIITVSMEIRDPYGEWLPDGVEGEVCVRSPFVMLGYWEDEAATAAAIAPGRWLRTGDYGLVENGRLRLTGRRSDLILRGGENVYPTEIEQCLDEHPEVLECAVIGTPHEDLGQEVAAVVVLRPGAAATEAELREYAADRLSYFKVPTRWRITTDLLPRNATGKMVRRDITV
What is the function of this protein?
Involved in cholate catabolism (PubMed:23024343, PubMed:24244004).  Catalyzes the transformation of cholate to cholyl-CoA, thus initiating degradation of the C5 cholate side chain (PubMed:23024343, PubMed:24244004).  Can also catalyze the ATP-dependent formation of CoA thioesters of deoxycholate and chenodeoxycholate (PubMed:23024343).
What are the official names of this protein?
Steroid-24-oyl-CoA synthetase, Cholyl-CoA synthetase, Steroid-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HNRH2_BOVIN
Sequence: MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDQNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGISNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDYQSNLA
What is the function of this protein?
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Binds poly(RG) (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, Heterogeneous nuclear ribonucleoprotein H', hnRNP H'.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: SYFA_MYCBP
Sequence: MLSPEALTTAVDAAQQAIALADTLDVLARVKTEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATLRAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELAEGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQIRTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLRGTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWGGCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BIFLO
Sequence: MSLIDQAKEQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKALRNSDLGISPNRDGNVIRLTMPELTEDRRKEYVKLAKGKAEDGKVAVRNIRRKTKETIDKAVKDGEMGEDEGDRLLKDLDKVTKSVTDEIDTLLETKQKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_NOCFA
Sequence: MTIRVGVLGARGKVGQAICAAVRAADDLELVAEVDKGDALETFTETGTEVVVDFTHPDVVMGNLKFLVEHGIHAVVGTTGFDAARLDEVRGWLAASPATGVLIAPNFAIGAVLSMRFAEQAARFFESVEVIELHHPNKADAPSGTAYRTAGLIAEARNRAGVGRSPDATSTELDGARGADVDGVRVHSVRLAGLVAHQEVLFGTQGETLTIRHDSIDRSSFAPGVLLGVREIGKRPGLTVGLDPFLDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTH1_ASPFU
Sequence: MTADVKSAAARILSTDSSRDPSFNNFSFTPFLRKSFGFGLASDVPVCKAYSEGHCPLGPACPDRHPTPSRVTTSTTTASGLAPSTTHGSLVCKHFLKGLCKKGLKCEYLHEYNLRRMPECQSFSRSGYCPNGDDCLYQHVREQARLPPCENYDQGFCELGPLCSKRHVRRRLCKYYLAGFCPEGKACPDAHPRWSENLPKPTMRVEKTEEELERERALIREEQEREKEREREWRSERGRGGGFMRGRYRGRGRG
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
mRNA 3'-end-processing protein yth1.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EIF3L_SCLS1
Sequence: MSAFQNGGIASRALDDDSDIEEEALANDYKEQVQYEGMEELEQVNSMSMAQQTDDIQSRLAAAAQPLDFSAPLEVKFASYDNYCSLFHFILNSDGPVDLEPPSYYWAWDVIDEFIYQFNSFCSYRNRVARQGTNEEEIQILREAPNTWGCYSVLNVLYSLIQRSQINEQLAAMRRNEEPMAVAGDYGSKSLYRMLGYFSIIGLLRVHCLLGDFSLALKTLDDIELNKKAMFARVMAAHFTTYYYVGFSYMMMRRYADAIRMFSHILIYVSRTKNFQKNAQYDSISKKNDQMYALIAICVAFHPTRLDDTIHTALREKYGDQLLKLQRGGPESLPIFEELFRSACPKFISPTPPDFDNPELNVDPLEHHLSIFMDEVKTNMWSPTVKSYLRLYTTMDLKKLAGFLEVEPEKLRGWLLVNKQRSRQIRWTDNGLLDGEVVNSNDLDYAMQGDLIHISEAKVGRKLVDWYLRNLARTY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_CROS8
Sequence: MMEFIYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPLKPIVGLADSKKLSEKRRLALFDEIKEKAIAWSLGRAEPHEIDELNILHATMLAMQRAVAGLAVTPEYVLVDGNRCPALPMPSMAVVKGDSRVAEISAASILAKVTRDAEMAELDLTFPQYGFAQHKGYPTAFHLERLAEHGATAHHRRSFAPVRRALGIAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAE_PROM9
Sequence: MAISRGDLVRVKRPESYWYNEIGKVASVDTSGIKYNCVVRFDKVNYAGISGTEGGANTNNFAESELEKA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RLUE_VIBVU
Sequence: MSFRSSSTSPRSNKQTATKRFKQSGQAQSVGSPKRHSVKRKNNEQSKKSLSLAERKIIIFNKPYDTLSQFTDGEGRKTLADFIPVKEVYAAGRLDRDSEGLMVLTNDGILQAKLTQPKSKSPKTYWVQVEGAPTEAQLEPLRRGVELKDGLTLPAQVEIIQDPQLWERNPPVRFRAAIPTTWLAITIIEGRNRQVRRMTAHIGFPTLRLVRYSMGGMTLQDLQPGEWKEISLPS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: IF12_BURO1
Sequence: MAKEELLELDGIVDEVLPDSKYRVTLENGVVVGAYASGRMRKNHIRILAGDRVTLELSVYDLTKGRINFRHKDANSPRPPRSGQPRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
Protein: TMEDA_DICDI
Sequence: MMNNKLLLLVIALLCIASNSIVESFSFKVSAKVEECIYEEIGVDLSFTAMFQVIQGGFNDIDFTIISPDKRIVYSGQRESEGTKTLRSSFAGVYSFCFSNKMSSLTDKTVSFILSVGESSPIREIAKKKDLTPIERSIMTLSDGVIAVKNEQNYFKMREAAHRNTAESTNSRVLWWSVFEAFVLIALSIWQIYYLRRFFEVKRAV
What is the function of this protein?
Could have a role in the budding of coatomer-coated and other species of coated vesicles.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein A.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Protein: AQP1_BOTFB
Sequence: MTMRSPLTNDHPQPLRASPLSEHDDEIQIRLDDSRYRSFPPPRRVVQRNTPAPIQLQDFEFPKQSHDIPGHYPMIDEIYPDVHPYRTSEDGFVSLTNGDNMAQNKRASRSRPWMQNLQTQDRIQRYKKRRPATKWMKWMNSDWKNHIVAVIGELIGTSLFLFFGYAGIEVAKLQGREPPDLEVLFYISATFGASLMVTAWIFFRISGGLFNPAVTLALAILKAVSPIRAFLLVITQLGASCLAAILVQEIFPKQLDVATTLGSGTSMGQGFVIEAITTAALIFTIIMLAVEKHKATFVAPIGIGLALFVAHMVAVPFTGASLNPARSFGPSAIVWNFPREHWIYWVGPILGAGLAVLFFRLIKLMEYEMANPGQDGDPENDPTQNPELDVAQNAHEREEEVLGLSNGKSWYRDDSSSGSMRRKESVNSFTGGRRSMDRRGDIFRRLDDVEAQWRRQQYRNVV
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes (Probable).  Involved in conidiation (PubMed:26527167).
What are the official names of this protein?
Aquaporin-1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: PX11E_ARATH
Sequence: MTTLDLTRAELALIVLYLNKAEARDKICRAIQYGSKFLSGGQPGTAQTVDKNTSLARKVFRLFKFVNDFHGLISPVPKGTPLPLVLLGKSKNALLSTFLFLDQIVWLGRSGIYKNKERTELLGRISLFCWLGSSVCTSAVEIGELGRLSSSMKKMEKELKADDELYRAKLQKSNDRTLALIKSSMDIIVAIGLLQLAPKTISPRVTGAFGFTTSLISCYQLLPSRPKLKTP
What is the function of this protein?
Involved in peroxisomal proliferation.  Promotes peroxisomal duplication, aggregation or elongation without fission.
What are the official names of this protein?
Peroxisomal membrane protein 11E, Peroxin-11E, AtPEX11e.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: EF2_NANEQ
Sequence: MVSEKTMAERVLALMGRPNNIRNIGIIAHIHHGKTTLTDNLLAGAGMLSEELAGDAMFTWWHEQEREREMTIYGAAVSMVHEYEGDDYLINLIDTPGHVEFGGEVTRAVRAIDGAVVVVDFVDGIMPQTETVLKQALREYVKPVLFINKVDRAIKELQLPPNKIMERLAEIVVGVNDLIERYAPEEFKDKWKVSVQNGTVAFGSALHNWALSVPYMQKTGIGFKQIAEIYNTAADAKEIRRRVWEIAPLYRVVLDMVVRHLPSPKEAQKYRVPKLWHGDLNSKYGKAMLEADPNGPAVAVVTKVIVDKTSKQETAIARVWSGTIRRGMEVWLLNANKKVRLQQVGVFKGIQKIQIEEAKAGNIIAISGVRDLQSGETIVEPEPDGSKPNIPPFEAIKHIFDPVVTKAIEPKDPRDLPKLIEVLKLIQKEDPTLKVEIDQESGQILISGLGDLHLEIVEYRIKNDFKVDIITSNPIVVYRESVKGQAGPVEGKSPNKLNKFYITVEKMPDELYWKLREKLLKGELPEGKIKKMNEDIIKHLMSLGFTREEAQRCKVIYRENMFFDMTRGIIHIGEVIDMVMDAFMQVMDHGPIAWEPCIGLIVKLTDAQLHEDAIHRGPGQVIPAVREAIKLAMKDAGLVLYEPVQVILVDVPPDYIGDVTALINSRRGAILDIQTEEDRALIKAKVPVREMIGFTDTLRSATSGRGVWYLVDQVYEPVPRELFDQIVREIRQRKGLPLDADIV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.