PharMolix/UniProtQA huggingface dataset:
Protein: HISX_BRAOC
Sequence: MSFDLSRLSLTSSPRLSFLTRTATKKGFVRCSMKSYRLSELSFSQVENLKARPRIDFSSIFTTVNPIIDAVRSKGDTAVKEYTERFDKVQLNKVVEDVSELDIPELDSAVKEAFDVAYDNIYAFHFAQMSTEKSVENMKGVRCKRVSRSIGSVGLYVPGGTAVLPSTALMLAIPAQIAGCKTVVLATPPTKEGSICKEVLYCAKRAGVTHILKAGGAQAIAAMAWGTDSCPKVEKIFGPGNQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADEHASPVYIAADLLSQAEHGPDSQVVLVVVGDGVNLKAIEEEIAKQCKSLPRGEFASKALSHSFTVFARDMIEAITFSNLYAPEHLIINVKDAEKWEGLIENAGSVFIGPWTPESVGDYASGTNHVLPTYGYARMYSGVSLDSFLKFMTVQSLTEEGLRNLGPYVATMAEIEGLDAHKRAVTLRLKDIEAKQTQTK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, chloroplastic, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OGT_METS5
Sequence: MIRYGTYMSPFGPITLVSEDEKIVMLDFCKCAEESLVDNNSFVGLFKKLDNYFQGKRTDFDDIPIRLNTNSFRMRVYKEVRKVKWGEVVTYKDIAEAVGTSPRAVGVALSKNPILLLIPCHRVVAENGLGGYSRGVELKRKLLELEGSLIKVPSIK
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_TOLAT
Sequence: MAKGAREKIRLNSSAGTGHFYTTTKNKRTMPEKMEIKKFDPVVRQHVIYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YUEC_BACSU
Sequence: MLSFSLFIPSAAAAQTEENTDVAPNQYEKKDIEIDTNYLHEDTYYEEKTELPEEQKDITFDKPKDKDAELIKDLFTSTNAEDSNTIAAQSKQLGITFAEKPMTKTSSTETEDEQETSSLLLPMIYVVLILLGIAGIVFLIPKVTAQENKKA
What is the function of this protein?
Required for YukE secretion.  Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
What are the official names of this protein?
ESX secretion system protein YueC.
What is the protein family that this protein belongs to?
Belongs to the EssA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DFP_LOCMI
Sequence: MKLVVAAVLAMAASRWRRLSAHGQVPSSTCADMLPVHGNAMPSTALPYTITVSPTSVNGGDTVRVHISGTEEFRGVYLQRGGAKSSRRVPAARRREQQDRPVRLPAGHNNAFSYISRTPLDTLDIDWKAPYTSDEIVFRATFVKSFSEFWVGVESPKITLGPLRQLDNAVAA
What is the function of this protein?
May have antimicrobial activity.
What are the official names of this protein?
Putative defense protein, Basic 19 kDa hemolymph protein.
What is the protein family that this protein belongs to?
Belongs to the insect defense protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN202_HUMAN
Sequence: MATAVEPEDQDLWEEEGILMVKLEDDFTCRPESVLQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVHLGVEPESPNELQDPVQSSTPEQSPEETTQSPDLGAPAEQRPHQEEELQTLQESEVPVPEDPDLPAERSSGDSEMVALLTALSQGLVTFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVSLSFPIPRPDEISQVREEEPWVPDIQEPQETQEPEILSFTYTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQTPDWEIVFEDNPGRLNERRFGTNISQVNSFVNLRETTPVHPLLGRHHDCSVCGKSFTCNSHLVRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAERTPSVEKPYRCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCGECGEDFSEHRRYLAHRKTHAAEELYLCSECGRCFTHSAAFAKHLRGHASVRPCRCNECGKSFSRRDHLVRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTHSEKTS
What is the function of this protein?
Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism.  Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.
What are the official names of this protein?
Zinc finger protein 202, Zinc finger protein with KRAB and SCAN domains 10.
What are the subcellular locations of this protein?
Nucleus.
Protein: MARH4_MOUSE
Sequence: MLMPLGGLLWWWCCCCGWYSCGLCTPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPPAPLPMHGDPQLPGVAANNNTLPALGAGGWAGWRGPREAVGRETPPLPPPPPLPPSGDDDWDGPATGPPASLLSSASSDEFCKEKTEDCYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQIAAAILGSLFLIASISWLIWSTFSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYRIFKRWQAVNQQWKVLNYDKTKDLEDQKSGGRTNLQTSSSAQANLPSAEEEAASPPAREEGPTRAASHPSGPVSQHHCAYTILHILSHLRPHDQRSTQGSGRELVMRVTTV
What is the function of this protein?
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, MARCH-IV, RING-type E3 ubiquitin transferase MARCHF4.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: BCHL_PELPB
Sequence: MSLVLAVYGKGGIGKSTTSANISAALALKGAKVLQIGCDPKHDSTFPITGKLQKTVIEALEEVDFHHEELSAEDIIETGFAGIDCLEAGGPPAGSGCGGYVVGESVALLQELGLYDKYDVILFDVLGDVVCGGFSAPLNYADYAIIIATNDFDSIFAANRLCMAIQQKSVRYKVKLAGIVANRVDYVTGGGTNMLDQFAEKVGTKLLAKVPYHELIRKSRFAGKTMYAMEDTPDKEECLKPYNEIADFLIQESPIASVPVPIGDREIFKMVNGWQ
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: LPT_KLEP7
Sequence: MNRIGMITTIITTTITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: HIS4_MOOTA
Sequence: MLVMPAIDLREGRCVRLYQGRIEAETVYSTDPVAVARGWVERGARWLHVVDLDGAFAGRPRNLEVIAAIIRAAGVPVQVGGGIRSLESLAGVLAAGASRVVLGTVAITNPEVVATAVERYGERVVVGIDSLDGQVAIEGWEATVARGAVEFARQMASLGVTRAVFTDIGRDGTLQGPNIAATREMARSGGLKIIASGGIASLDDLRKLKELAAEGVEGAILGRSLYNGNFTLEEALAVAADGD
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_ECOLI
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAG_ECOLI
Sequence: MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQILEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARANNSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKGYTRKQVRLLCEWYLRVRKSS
What are the official names of this protein?
Uncharacterized protein YeaG.
What is the protein family that this protein belongs to?
Belongs to the PrkA family.
Protein: C05AK_ARATH
Sequence: MEAVISFDFQNCFIFILIFLLTFLCFFFFFKKPKDSRVNFDLPPSPPSLPIIGHVHLLLSTLTHKSLQKLSSRYGPLLYLRIFNVPIILVSSASVAYEIFRTQDVNISSRGVTAVDESLVFGSSSFVTAPYGDYWKFMKKLTVMKLLGPQAQEQSRDIRADDIKRFCRNLLDKARKKESVEIGKEAMNLMNNILCKMSMGRSFSEENGETEKLRGLVTESIGLMKKMFLAVLLRRQLQKLGISLFKKDIMGVSNKFDVLLEKVLVEHREKPEKDQGTVMLDVLLAAYGDENAEYKITKNHIKAFFVDLFIGATDTSVQTIQWTMAEIMNNTHILERMREEIDSVVGKSRLIQETDLPNLPYLHAVIKEALRLHPPGPLLPREFQQGCKIGGFYIPEKTTLLINAYVVMRDPNVWEDPEEFKPERFLASSRSGQEDERREQALKFLPFGSGRRGCPGSNLAYMIVGSAIGMMVQCFDWRIEGEKVNMKEAVKGTILTMAHPLKLTPVTRQPPLTWI
What is the function of this protein?
Plays a role in the gravitropic response of the inflorescence stems and roots.  May affect the synthesis of flavonols that have a role in regulating auxin transport.
What are the official names of this protein?
Cytochrome P450 705A22, Protein GRAVITY PERSISTENCE SIGNAL 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: APT_MAGSA
Sequence: MNIKDHIRGVPDFPKPGILFYDISTLLAHPDAWQVAMGRMAREIIKFQPDVLAGIDSRGFLVAAPLALKLGCGFVMLRKKGKLPGETIRHDYALEYGTDTIEIQKGAIEEGKRVVILDDLLATGGTMAAGVELLRKIGAHVTGAGTIIDLAFLPGKQRLKELDVPFTCLASYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCK_CHICK
Sequence: MATPPKRGRLEGRVKKIAVEGNIAAGKSTFVNILKQADEGWEVVPEPVARWCNVQQNSEEDCEELTTSQKSGGNVLQMMYEKPERWSFTFQMYACLSRIRAQLKSIDGKLREAENPVVFFERSVYSDRYIFAANLYESDCMNETEWTIYQDWHDWMNKQFGQSLALDGIIYLRATPEKCLNRIYLRGRDEEQEIPIEYLEKLHYKHESWLQHKTLRTDFEYLQEIPILTLDVNEDFKGKKDRYDHMTEKVKEFLSTL
What is the function of this protein?
Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine (PubMed:27906638).  Displays highest activity against deoxycytidine followed by deoxyadenosine and then deoxyguanosine (PubMed:27906638).  Shows only very minor activity against deoxyuridine and deoxythymidine (PubMed:27906638).
What are the official names of this protein?
Deoxycytidine kinase, GgdCK, Deoxyadenosine kinase, Deoxyguanosine kinase.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCKA_RUEST
Sequence: MTSGRVNPNFRLEDQGIEGLGNVYYNLMEPALVQEALSRGEGNLGKGGAFLVTTGKFTGRSPKDKHVVKTASVADTIWWENNAEMSPEGFDALYADMVEHMKGRDYFVQDLVGGADPVHAINVRMVTELAWHNLFIRHLLRRPDREDLDDFIADFTIINCPSFQADPNKHNCRSETVIALNFDRKMILIGGTEYAGENKKSVFTLLNYLLPEKGIMPMHCSANHAKGNPVDTAVFFGLSGTGKTTLSADPDRVLIGDDEHGWASNGTFNFEGGCYAKTINLNPEAEPEIYATTEKFGTVIENMTFDPETFDLNFDDDSLTANMRCAYPLHYISNASASARGGHPKNIIMLTCDAFGVLPPIARLTPAQAMYHFLSGFTSKVAGTERGVTEPEPTFSTCFGAPFMPRRPEVYGNLLREKIAAHGATCWLVNTGWTGGAYGTGSRMPIKATRALLTAALDGSLANAEFRKDPNFGFDVPVAAPGVAEVLLDPRRTWDDKAAYDAQAEKLVQMFSDNFEQYLPYIDEDVKAAAIC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABCA3_DICDI
Sequence: MGEFKFQLVTLLKKNSLLKGKSKIKFIGEILAPMIVIGILFGLLYLSAIIQPDFSPRYASGFTEVVGRLKKLLVATNGPLVPYQQTIVNNLRKQIKLAHPDYTNEYIDQCFEIFQDFESMQGYFLDPENYRGVMGGLWFDENDYRYNAPKVLKYSISVDADYTNDNNIQISPRSDSQIYLRHYFTQIQTAVDQAIFMAQNVEIPMVVTGQRFPNPYIHLWQTWTDGRNMILKETGGIFITAAIFVGLFTTITNMVMEKESKILEAMKIMGLHSLPYYVSIAISSCYTIIPSTIIVIVVLKGSQLIWTTQWYILTIILILFSISLILLAFILSKFFNRSKFAGLVCFLIVLIMAGIGIAVNHINVSTTVKLIFCLLSPVAISLANYSMSMKDLELVKIVNPDWSIIVSENQVIGMLILDVVLYAALVWYIDNIISGEFGQSKPFYFFLTKSYWCKKNANENDLVDLSKAIESPLYLRKKDLDYNNSQDFELNEIHSSKATIQIRKLRKEFKTGDGKRVAVDDLSIDMYQDRIHCFLGPNGSGKSTTIGMLTGLITCTRGSALINGLDINQNIDLIRKNIGVVLQQDIIWDNLTVLEHLIFYAQLKGYSNLKEAKTEAKKMGIEVGLELKLHNKAGTLSGGQKRKLCLGIAFIGPNSNILFLDEVSSGLDPLSRSEVQDFIISKKKGKTIILSTHYMDEADLLGDTISIIAHGKLKCNGSPLFLKNRFGVGYLLTITKKSTEFNKDSVMEITNKYIKQAHILSDAGTELSIRLPMESLPMFSQYFKHLEDCKNQLLIDSYGISISTLEEVFLKIGQETLKSTPNFNDPAVKEALSTKSSGVKVGQQLKGLLIKRICTTKKDFKSFMFSIVVPLIILALGLVMYKNMRTIETFNDVTTPLTFSIDDYGDNIYVPWSISGQNQAIDLRIKNSIGKSNHSKLLPADELEDYLTLNYEGNPGAFAFGKTIIEDIEMLSFKVYYNRDYLHALPIYINFVDNLMLSNLGGVGIQTTSRPFQHIKSKFELATEKINFSAIIFFIILTLAAFALVVASHAGNIAQERAARIKRLLYISGLKKYVYWLSNLIWDYVLTFIMVIFLAVVVVIIDSKFRNQFPLFICALVLFVTAIIPLSYLFSYCWSSHGKATGFIFGIHFGIGLLMTVTCFILRIWVIKDDNDILQTITDIIDLVFFFFSPFYCFSKVMVIISNFPGTTRLGESYIANYWGIKFGLPPVCFLALHTLVWTIWIMVLDYYPELRGKYRKGRNEKSSPPPPSDEDSDVSHERSKVLSFETSNDPIIMRDFFKLYKGKGKAKDNLAVYNTSLSIPKGQTFGLLGLNGAGKSTTLGCLSGEVIPSGGEIFVNGFNIQTQRLDALRSVGFCHQYNSLIGLLSAREQIRLYCRIKGIEESKIQETVEAFIKMMDLGSIGNSNVAGYSGGNKRKVALSVAIVGNPSVCFLDEVSAGVDPVVARFMWNVITELKKDKVIILTTHSMLECSAVCDRLTIMKSGKMMCLGSIQHIKDKFGSGYSIDVKFKKEYLLSGINLFQKELPNAKLVDHHDLSASFELPNSLDSPIQLSKIFSIIERNLKPILNDYSVGQTSIDHIFLKLTNLNQQKIKNQQKESIENHIIDINNNNNNNNNNSYLKNHKKTTSNNSILTNNSTTKNFGSSNFLDLESDNTYLNNLKYLEDDDFNIEMPPYQNSLKKSF
What are the official names of this protein?
ABC transporter A family member 3, ABC transporter ABCA.3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UP08_FRUSA
Sequence: PYLLNLPPEK
What are the official names of this protein?
Unknown protein 8 from 2D-PAGE.
Protein: NCPR3_ORYSJ
Sequence: MDSGGGGGGGALRPSALDLVAALLTGRGRPEEEGWPPSLAENRHLIVLLTTSLAVLVGCGVALLVRRSSISAPAVRAQEPQPRAPAPAKRKQEAEPDPDDGRQRVAVFFGTQTGTAEGFAKALAEEAKSRYDKAVFKVLDLDEYAADDEEYEQKLKKEIIALFFVATYGDGEPTDNAARFYKWFGEGNERGEWLSNLRFGVFGLGNRQYEHFNKVGKVVDQLLAEQGGKRIVPLGLGDDDQCIEDDFNAWKELLWPELDKLLRVEDDKSAAPTPYTAAIPEYRVVLVKPEEAMHINKSFSLSNGHAVYDIQHPCRANVAVRRELHTPASYRSCIHLEFDISGTGLTYETGDHVGVYAENCTETVEEVENLLGYSPDTLFSIHADQEDGTPLFGGSLPPPFPSPCTVGTALARYADLLSFPKKSALIALASHASDPKDAERLRHLASPAGKKEYSQWIVSSQRSLLEVMTEFPSAKPPLGVFFAAIAPRLQPRYYSISSSPRMTPTRIHVTCALVYGQTPTGRIHKGVCSTWMKNSIPLEESQECSWAPIFVRQSNFKLPTDPTVPIIMIGPGTGLAPFRGFLQERLALKETGVELGHAVLFFGCRNRKMDFIYEDELNNFVETGALSELIVAFSREGPSKEYVQHKMAEKAPEIWSIISQGGYIYVCGDAKGMARDVHRTLHTIVQEQGSLDNSNTESYVKSLQMEGRYLRDVW
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes (By similarity) (PubMed:23053415).  It can also provide electron transfer to heme oxygenase and cytochrome B5 (By similarity).
What are the official names of this protein?
NADPH--cytochrome P450 reductase 3, CPR, P450R.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the flavodoxin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single- pass membrane protein; Cytoplasmic side.
Protein: GPSB_STAA2
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: PPK30_SCHPO
Sequence: MTEVYSKAPATVGQVKLSNNGTSNKAYSVPKSPAPVRTDLFSKIPAGTKIQVGSHSVIIQRYLSEGGFSHVYLALLENEKPFVLKRIYVPDKTALQLVHGEIETMKRLKGHRHIVNYIDSSALYSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADVCDAVAAMHYLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTIMFLEQNIAAYTTPQYRAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVGNSAILKASFSFPPFPRYSDRMKRFIATCLQEQPSHRPNIYQTLKEIMEMQGTPLKLPDVYGGVNASTYNPPRAPLQRTPSGSLTPLSSRPAHTSLPPIPTVQTTSSNVPPVNRPSLKSKSPSVSNILSNQLSPISSANNDVMARLQPKSPIPATKSYSATIQTPRSPSLRRADSTSHIIKVPHLPDTSVKTAKTGASEIDVLSRYPSVEEIDKITDKIEVSKPLRNSGPLAFKPFEKISANKQTDLLQNKPEALLDLENRFLPKPSPKPSEFSSSVGSKQNLSMDIPSVQNVSTKQKSTNDTDNSKLKINKPLTGGYAPLPSRPNRMNHSVLNEKSNKEFVRGPRVLPPIEVSSSKMAGLDIRKEPFTPAVPSAKSGLKKDQSSEVANKDVVSKNKDNIAILADREARPQLLLDDNNDSSSSSSEHLISFNNHTGNKILSRQTTSSSIDSNNVQSNIEFLKGLNATHARSTSQVSHTQRLQQSISTSLERVKSNTKKESNSPRQVSKLKRPIGASNKILSGKFGEAFKKFEFGGEKMSRRRKSETKKNLVSILPDTEVDEYPKASNEWIVESEELPQVHETINQYRKSCETQRSRKSHEGSNDLERQPSSPDTVHPGIKRSHFIRERVKQLLSDANKHHQSPSDSETDRTPDSSSIHLPHIERLNLFHTKSESLE
What are the official names of this protein?
Serine/threonine-protein kinase ppk30.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCYA_SYNS9
Sequence: MQPQSKDPCQELHPLVSTLAASIRSSWQKLPELAPLCTADDLKAIHGELDGETLFIGNELYQCRGFRKIHLEIARLGNGLQILHCVWFPDPQYDLPIFGADIVAGPAGISAAIVDLSPTSGELPDPVFKGLEAIERPAFRQVRDLPGWGTIFSSKVCFIRPDGADEEALFNQVVIDYLEVLSDCASRANPESPTTVSTINRYEGQLNYCLQQKRNDKTRRVLEKAFDPEWADRYIELLLFDNPPTP
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: AMBP_MESAU
Sequence: MLGLGTLFLLLAACPASRADPVPALPDIQVQENFNESRIYGKWFNLAVGSTCPWLSRIKNKMSMSTLVLREGATGAEISTTSTRWRRGVCEEVSGTYEKTDMDGKFLYHKSKWNVTLESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGREPQLRDSLLQEFREVALSVGIPENSIVFMEDRGECVPGDLEQKSTSLLRARRAVLPQENEGSGTGPLVTDVLKKEDSCQLSYSEGPCLGMIEKYYYNGASMACETFHYGGCLGNGNNFNSEKECLQTCRTVAACSLPIVQGPCRAYVELWAFDAAQGKCVQFSYGGCKGNGNKFYSEKECKEYCGVPGDGYEELTRS
What is the function of this protein?
Kunitz-type serine protease inhibitor.  Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation.  Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
What are the official names of this protein?
Protein AMBP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
[Alpha-1-microglobulin]: Secreted. Endoplasmic reticulum. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Secreted, extracellular space, extracellular matrix. Note=The cellular uptake occurs via a non-endocytotic pathway and allows for localization to various membrane structures. A specific binding to plasma membrane suggests the presence of a cell receptor, yet to be identified. Directly binds collagen fibers type I.
Protein: ISPDF_SOLM1
Sequence: MSLWTVLLAAGSGTRLAQASGGVKKQFLSVGGRPLYWKALTAFAKSPDVAGVVVVFAPEDLAEATRELAGFLDANHPGLPVLTAAGGARRQDSVKNGLDALPREARLVLIHDAARPFVDAGLIARVADALAAGRKAVIPTLPVTDTVKQVDGDRVTATLPRHELAAVQTPQGFDLTLLRQAYAHARPDFDVTDDASLVEHYGQPVFTVPGAPRNMKITHPEDLASLAEAAAPPVPVTGYGYDVHRYADPRNPGKQPPRPMKLGGFPILGAPEVLAHSDGDVLLHALTDAVLGCVAGGDIGRLFPDSNPDFDNMASGVFLSEALLAAKAKGLTITHVDLTIIAQIPKISPHAEAIRLNVAALLGLNKEQVNLKATTEEGLGFTGEKKGIKAVALVSGWRRP
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: PGK_LIGS1
Sequence: MAKLIVSDLDVKGKKVLMRVDFNVPIKNGVIGNDNRIVAALPTINYIIEHDGKAILFSHLGRIKKEEDKKELSLRPVAERLAELLNKPVTFVPATRGAQLEDAINNMNDGDVLLVENTRFEDLDGKKESGNDPELGKYWASLGDVFVNDAFGTAHRSHASNVGISEAMKAEGKQAAAGYLLEKEIKFLGNAVDSPKHPFVAILGGAKVSDKIGVINHLLGKADKVIVGGGMTYTFYAAKGIKIGNSLVEKDKIELAKEIMEKAGDKLVLPVDNVCAKEFNNDAPSEVVEGDIPDGYMALDIGPKSVELFEDTLKDAKTVVWNGPMGVFEMSNFAKGTLEVGKFLGTLSDATTIVGGGDSTAAVQQLGVADKLTHISTGGGASLEYLEGKTLPGIAAVSDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOPOM_MYCS2
Sequence: MTATLDVPEQNPDLVLDQSADDYWNHYQLTFALYSVSDRAIPSAYDGLKPGQRRLLYQMHDSKLLPGNKPQKSSKVCSAVTGNLHPHGGASMYGAAALMAADFQRVKVIDGQGAFPRIQGDIPAADRYTEMRLSAPGAALTAELNDHAVPMVPTFDGEWVEPTVLPAQWPVLLCNGAVGIAEGWATKVPAHNPREVMAACRALLKTPNMTDDRLCKLIPGPDWGSGASVVGTAGLREYITTGRGHFTVRGTISVEGKNCIITELPPGVASNTVQDRIRALVESGEMSGVADMSDLTDRRNGLRIVVTAKRGHNAEQIRDQLLALTPLESTFAASLVALDENRVPRWWSVRDLIMAFLQLRDSVVLHRSEYRLEKVTARRHLVAGLMKIHLDIDAAVAVIRGSETVDEARKGLQERFKIDAEQADYVLSLQLRRLTKLDVIELQAEAEKLDAEFAELNDLVTNPESRRKVIDKELVETAKLFKGPEYDRRTVLDFDATPVSRGDEDGSRERKVNTAWRLDDRGVFSDSHGELLTSGLGWAVWSDGRIKFTTGNGLPFKIRDIPVAPDITGLVRSGVLPEGYHLALVTRRGKILRVDPASVNPQGVAGNGVAGVKLAADGDEVIAALPVSCANGEAILSIAEKSWKVTEVADIPVKGRGGAGVAFHPFVKGEDALLAASISKTGYVRGKRAVRPENRAKASIKGSGADVTPAPAE
What is the function of this protein?
Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides.  Individual subunits have no activity.  Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA.  Relaxes positive supercoils in an ATP-dependent manner.  Catenates and decatenates DNA.  Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase (PubMed:16313624).
What are the official names of this protein?
Topoisomerase subunit TopoM.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.