PharMolix/UniProtQA huggingface dataset:
Protein: TIG_BURTA
Sequence: MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISRSENLRVAGQPSFAPKQDAAQEGAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTSAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKTGEAREFDLKFPDDYHGKDVAGKTAQFTVTMKKVEWPHLPAIDADFAKSLGIEDGDLTKMREEIKENLGREAKRRTQSIVKNQVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPVEMFAEQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: STU1_CANAL
Sequence: MSTTKFNSISPIELLEIISSYDIQDEIKLSHIQNLKTHIKKDTIDLRNVPIYLQIITKGLEITRLNISSVSFNSLSYLIKRISVQDKSGNILKEECFLILPILINKLGNASSPAGTNSAKKSLEDYWLSSPIEVEDALTEIAFENPNTKITIETIDWMTQILKNISAKFNVPKFLPKILHSIEINPHNEEIIVSTKELLSIYLEKNPSAIEGFKKQIESHSLAQATKDKLLGSVISKLRGSDPEPHVQRANTPRSNTPVSQIQSSLVDVGHDVELLELLNKVNYEIDSSIKALDIRDANSLFNTFEIFMPCFDGKETESNWKVREKNILQMRSILRGNSATQFRSELVQCIHTIANGMCKGASSLRTTLSSNSCQLIKECAVILKKSLEPVAESLFPTLIKLCSSTKNIASTNANMSVAALYANLPYTSKMIQRITLASEDRNYQPRSYSLIWLHILLLKIGIDRSYIGHHDSSFIEAANKVFMKLLKDANPNVRQTAKECYWCFTRVFPEDAERLLKRLEPNIVRALERSQRESGGSGIAPIRTLSSRPSRPSLKEAILEKNKELRQRRPPSRNSGEQSTKIKSVPLPRPTKSSSRLEKSLLRPDVGHKSQPAVRASSWTYPSTQSGPKATFKQRERSKTEVHKKSPLEISRPSSRLDTGAVSSFNNKNDPMINFLSSSDSDLIKEGINLLKYAIIGKENLPSEINSLLKSISEKHVQFMKPLFTSNDYTFKKAASLLLPDDFLRVCALVFDEFDEAVISLIIQCIDVSTFYESACNLLTLVADTPNIPGSHALVMQISNQKLTITKSILQALSIALSKHAVTDVQFGEIFQELVKLIIVLKATDYYSLLCQLFRQLYTIDSNKFSLLVEDVEGKLKEEVEFIVGIESTMTLERPSSKLDYDLTVVKPTSNLGTFVLSQKPSADDFTMLLPKRSEFLGSGEVYNSKMVAKIEASDSSPQKQSQMDQISSKRSNSEHQSEVLVDDFANVSIADGGGSKLNQSKNDDDNLKQFMERIDPLKPISNKIRKISIYEDAKQNSEKPKLERNWGGFQYAKFSRAIRVNAVAENMSLTSQEFESCCSKLVETPSQSALLKMTWFVDSLSVSSYDYQEFFLNKGKHKLEKSLWEFFSKIDKSDHSLVMNGLFLLKQLLKFNDTPNVDKLFALLVDTCSQEELDSELYFIWNEMLLSLNHDELMKSFEKNALNYLEGEENNLTISSLCLNYLAKVLVDDNCLDVAKIYRLDTIFGKLFHEREVMFRKSATICYSNLLKNTNVSPEVKDTLDKVKSRYPASTQRLIEFYMKR
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein STU1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: PURA_XANOP
Sequence: MGQSVVVLGAQWGDEGKGKIVDLLTEEIGAVVRFQGGHNAGHTLVINGKKTVLHLIPSGILRDDALCLIGNGVVISPAALIKEVSELEDAGVEVRSRLKISPAAPLIMPYHIALDQAREKAAGGKAIGTTGRGIGPAYEDKVARRGIRIADLHYPPQLEELLRTALDYHNFVLTKYLGVEAVDFQKTYDEALAFGDYVQPMKSDVAGILHDLRKQGKRVLFEGAQGALLDIDHGTYPYVTSSNTTVGGALAGTGVGADAIDYVLGIAKAYATRVGGGPFPTELDDEVGQGIRDRGAEYGASTGRPRRCGWMDIVALKRAVAINGISGLCITKLDVLDGMEKLKVCIAYEYRGKRTEYAPLDAQGWEECTPVYLEFPGWTENTHGITEWDKLPVAARAYLRALEELAGCPISIVSTGPDRDHTMVLQDPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ALIF1
Sequence: MHCPFCSATDTKVIDSRLVSDGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFDEDKLSGGLYRSLEKRPVSADLVELALNTIKSQLRATGEREVPSDMIGNLVMDQLKELDKVAYIRFASVYRSFEDIKEFGEEIAKLEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ISPF_HALHL
Sequence: MIRIGQGFDVHRFAGKGEGFRLGGVAVPYHKRLEAHSDGDVLLHAITDGLLGACGMGDIGRHFPDDDPRWRDADSIGLLASTLRLAAEAGWVPVNVDGTVIAQAPKLAPYIGAMRQATADAMELSPGAVNVKATTSERLGFTGRGEGIAAMAVVLVESAPGRG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TRHO_MARMM
Sequence: MPRFLVAALYKFAPLDADGKLQADLKSACEHHNVFGTLLLAPEGINGTIAGPSAGVHVILAELRALPGFDTLEHKESHADTQPFLRMKVRLKREIVTMGVTDIDPVDDVGTYVEPEDWNDLISAPDVVTIDTRNDYEVRIGQFEGAINPHTVSFREFPDWFRQFRETRPDARIAMYCTGGIRCEKATAFARMEGVDDVFHLKGGILKYLETVPEAQSRWRGECFVFDRRVAVKHGLELGSHTLCHACREPLGPEDLRSPDHVVGVSCPHCVEGRTPEQRERYAERHRQEEMARARGEWHLGQPGAVRETDG
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RSMH_BACC3
Sequence: MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDVVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVITFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR1BD_BACTZ
Sequence: MTSNRKNENEIINALSIPAVSNHSAQMDLSLDARIEDSLCIAEGNNINPLVSASTVQTGINIAGRILGVLGVPFAGQLASFYSFLVGELWPSGRDPWEIFLEHVEQLIRQQVTENTRNTAIARLEGLGRGYRSYQQALETWLDNRNDARSRSIILERYVALELDITTAIPLFRIRNEEVPLLMVYAQAANLHLLLLRDASLFGSEWGMASSDVNQYYQEQIRYTEEYSNHCVQWYNTGLNNLRGTNAESWLRYNQFRRDLTLGVLDLVALFPSYDTRTYPINTSAQLTREIYTDPIGRTNAPSGFASTNWFNNNAPSFSAIEAAIFRPPHLLDFPEQLTIYSASSRWSSTQHMNYWVGHRLNFRPIGGTLNTSTQGLTNNTSINPVTLQFTSRDVYRTESNAGTNILFTTPVNGVPWARFNFINPQNIYERGATTYSQPYQGVGIQLFDSETELPPETTERPNYESYSHRLSHIGLIIGNTLRAPVYSWTHRSADRTNTIGPNRITQIPAVKGRFLFNGSVISGPGFTGGDVVRLNRNNGNIQNRGYIEVPIQFTSTSTRYRVRVRYASVTSIELNVNLGNSSIFTNTLPATAASLDNLQSGDFGYVEINNAFTSATGNIVGARNFSANAEVIIDRFEFIPVTATFEAEYDLERAQKAVNALFTSTNPRRLKTDVTDYHIDQVSNMVACLSDEFCLDEKRELFEKVKYAKRLSDERNLLQDPNFTFISGQLSFASIDGQSNFTSINELSEHGWWGSENVTIQEGNDVFKENYVTLPGTFNECYPNYLYQKIGESELKAYTRYQLRGYIEDSQDLEIYLIRYNAKHETLDVPGTDSLWPLSVKSPIGRCGEPNRCAPHFEWNPDLDCSCRDGERCAHHSHHFTLDIDVGCTDLHENLGVWVVFKIKTQEGYARLGNLEFIEEKPLIGEALSRVKRAEKKWRDKREKLQLETKRVYTEAKETVDALFVDSHYNRLQADTNIGMIHAADRLVHRIHEAYLPELPFIPGINAVIFEELENRISTAFSLYDARNVIKNGDFNNGLSCWNVKGHVDVQQSHHRSDLVIPEWEAEVSQAVRVCPGRGYILRVTAYKEGYGEGCVTIHEIENNTDELKFKNCEEEEVYPTDTGTCNDYTAHQGTAACNSRNAGYEDAYEVDTTASVNYKPTYEEETYTDVRRDNHCEYDRGYVNYPPVPAGYVTKELEYFPETDTVWIEIGETEGKFIVDSVELLLMEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of lepidopteran larvae.  Toxic to Plutella xylostella.
What are the official names of this protein?
Pesticidal crystal protein Cry1Bd, 140 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIB(d).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: GLRX1_RABIT
Sequence: AQEFVNSKIQPGKVVVFIKPTCPYCRKTQEILSQLPFKQGLLEFVDITATSDMSEIQDYLQQLTGARTVPRVFLGKDCIGGCSDLIAMQEKGELLARLKEMGALRQ
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins.
What are the official names of this protein?
Glutaredoxin-1, Thioltransferase-1, TTase-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MICS1_CAEEL
Sequence: MMVSPPQEDTVFNTDSDPVYEQATDDMTFNDTTTDGNGQESVPLEALTVVEIEKTSKGFGFNIVGGTDNPHFVGDIGIYVSSVNSESKSYGVVRTGDKILSFDGIDMTYKTHDEAVEVFRSVKIGHVAKMLIDREYLHLQEDRTQTPTASVSITPQVTPQTRSTQNNTDTPKSMSHSESKSRLTSHGLSAVIERIRGKVYEEEDAQSVTSYAPSTHSIIDDVPRTPRKPLSLLDPRNNSWLTEALYVSIGLGALTISGYLAYRFIRGRR
What is the function of this protein?
Plays a role in the regulation of lifespan in a partially daf-16-mediated manner, and may be involved in regulating the levels of reactive oxygen species production in response to heat stress.
What are the official names of this protein?
Mitochondrial scaffolding protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PMIS2_MOUSE
Sequence: MDTDEQGAPGRKPLDRPQTPDELKFYARNYVMLALLAMILFLPFGILAIYFSIQTNEANKCSNWEDAYRNSSRTMWFNMLAIVAFVGIIYILVLVL
What is the function of this protein?
May play a role in spermatozoa mobility.
What are the official names of this protein?
Transmembrane protein PMIS2, Protein missing in infertile spermatozoa 2.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BTGC_ASPFC
Sequence: MSGPNRTYSFGEGDDGLAHPSSRTHAMHSQYDDVSPISDGARMNPMNGQGMDHGLASVLEDGRQGWGRSPEPSPSLLTGSSATPGMDNLGPGAVGGGISGIALSVANSHDRLSGVEALMGTDGQEANIPAERGLSTTGSDNPYVPEPPEYRYSYGSNIALGAAAAPAGQLTPGQSVSHLSSTNPSQRNLYDIPYQDVGGLNAGPYQRHSAYSSNDLPVDINPDEIVDDGDDGFVPAPNSGSGARKSQAIPAAAGGAAAGGVLGNLGGLFGGKSAADTSYGPVPGAGLEAGEKGRWVKPKPGGGNKKRGWIVGAILAFIIIGAIVGGAVGGTIGHRGNEEPSSASSASSSSTQTATEDTSVNGDLDKNSAEIKALMNNKNLHKVFPGIDYTPWGVQYPLCLKYPPSQNNVTRDMAVLTQLTNNVRLYGTDCNQTEMVLHAIDKLEIKDMKIWLGVWIDSNETTSRRQIDQLYKIIDDAKDISIFNGAIVGNEALYRAGSDKTSAQTTLINYMQEVKDHFKKKNIDLPVATSDLGDNWDATLVQAADVVMANVHPFFGGIPVDQAAAWTWRFWQDHNVALTKGTNKKQIISEVGWPSGGGNDCGQGANCPNDTAGAVAGVDELNKFMEDWVCQALDNGTDYFWFEAFDEPWKIVYNTGKENWEDKWGLMDSARNLKPGLKIPDCGGKTAT
What is the function of this protein?
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.  This enzyme may be involved in beta-glucan degradation.  Active on laminarin and lichenan (By similarity).
What are the official names of this protein?
Probable glucan endo-1,3-beta-glucosidase btgC, Endo-1,3-beta-glucanase btgC, Laminarinase btgC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MAS1L_HUMAN
Sequence: MVWGKICWFSQRAGWTVFAESQISLSCSLCLHSGDQEAQNPNLVSQLCGVFLQNETNETIHMQMSMAVGQQALPLNIIAPKAVLVSLCGVLLNGTVFWLLCCGATNPYMVYILHLVAADVIYLCCSAVGFLQVTLLTYHGVVFFIPDFLAILSPFSFEVCLCLLVAISTERCVCVLFPIWYRCHRPKYTSNVVCTLIWGLPFCINIVKSLFLTYWKHVKACVIFLKLSGLFHAILSLVMCVSSLTLLIRFLCCSQQQKATRVYAVVQISAPMFLLWALPLSVAPLITDFKMFVTTSYLISLFLIINSSANPIIYFFVGSLRKKRLKESLRVILQRALADKPEVGRNKKAAGIDPMEQPHSTQHVENLLPREHRVDVET
What are the official names of this protein?
Mas-related G-protein coupled receptor MRG, MAS-R, MAS1-like.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_MYCSJ
Sequence: MIDETLFDAEEKMEKAVSVARDDLSSIRTGRANPGMFSRINVDYYGATTPITQLSSINVPEARMVVIKPYEANQLRNIEDAIRNSDLGVNPTNDGNIIRVSIPQLTEERRRDLVKQAKAKGEDAKVSVRNIRRKAMEELARIKKDGEAGEDEVSRAEKDLDKTTHTYTHQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_VIBC3
Sequence: MDVSLPCIKIQVQTRYIEEQSNPEYQRFVFAYLITIKNLSSQTVQLMSRRWLITDADGKQTVVEGDGVVGEQPRIKANDEYTYSSGTALDTPVGVMQGQYLMIDEQGESFTVEIEPFRLAVPHVLN
What are the official names of this protein?
Protein ApaG.
Protein: Y0687_MYCTU
Sequence: MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGSVTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVADGVEQFGRLDIVVANAGVLGWGRLWELTDEQWETVIGVNLTGTWRTLRATVPAMIDAGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIRVNSIHPYSVDTPMIEPEAMIQTFAKHPGYVHSFPPMPLQPKGFMTPDEISDVVVWLAGDGSGALSGNQIPVDKGALKY
What are the official names of this protein?
Uncharacterized NAD-dependent oxidoreductase Rv0687.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HBA_CYGOL
Sequence: VLSAADKTNVKGVFSKIGGHADDYGAETLERMFIAYPQTKTYFPHFDLQHGSAQIKAHGKKVAAALVEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPSALTPEVHASLDKFLCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NUOB1_BURMS
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTSTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VATF_THEON
Sequence: MKIAVLGDKDTALGFKLAGAHEVYSFEDTPLDMERLKNKLNELVEREDIGIILITERFVQKIGLPDVTFPIILQVPDKSGSKFGEEAIKEIVRRAIGVELKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: Y3085_SOLM1
Sequence: MAGHSKWHNIQARKSVQDAKKSKFFTKVTKELMLAARAGGADTALNQRLKSAIAAAKAVNLPKDKIDQAIKKGTGELAGENLEEVLYEGYGPGGVAILVEAATDNRNRTVAEVRHLLSKGGGAMGESGCVSWMFSQKGVFSFPKTFTEDQLMEVGLEHGAEEIMDEGEVWEVHCAPADFEPLRAAFEAAGMVSEDAEVAMVPANMVALDLEAGQKLLKLIDMLEDNEDVQKVHSNADLPDEMFG
What are the official names of this protein?
Probable transcriptional regulatory protein DMR_30850.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSBP3_HUMAN
Sequence: MFAKGKGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPGFFQGPPGSQPSPHAQPPPHNPSSMMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNSMDPTRQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSLGPAMPGINMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPRDDGELGGNFLHSFQNDNYSPSMTMSV
What is the function of this protein?
May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.
What are the official names of this protein?
Single-stranded DNA-binding protein 3, Sequence-specific single-stranded-DNA-binding protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: CIAO1_MOUSE
Sequence: MKDSLVLQSRVPAHPDSRCWFLAWNPSGTLLASCGGDRKIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLSSHTQDVKHVVWHPSQELLASASYDDTVKLYQEEGDDWVCCATLEGHESTVWSIAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICTLSGFHTRTIYDVAWCQLTGALATACGDDAIRVFEEDPGSDPQQPTFSLTAHLRQAHSQDVNCVAWNPKEPGLLASCSDDGEVAFWEYHQPAGL
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity).  As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors.  The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins.  CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (By similarity).  Seems to specifically modulate the transactivation activity of WT1.  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I61A1
Sequence: MGQEQGIPWIL
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
Protein: TIG_GRABC
Sequence: MQVTETLSEGLKRGFTVQVPATDIEERRTRRLAELAKTLKLPGFRPGKVPMTLVRQRYGRSVETEVLEETVNEATQTMVSERGLRPALQPKVELVRVDLDQDVEFKVELELLPDITLPDLGSVSLTRLKAEPSAEAVDKALEEIAQRQRNLEPVEEVRPAQKGDFLTVDFVGKTDGVAFQGGTGTDMDVEIAGTGFIPGFSEQMEGLSVGETRVIDVTFPEEYGVPELAGKPAQFEITAKALKKAVAPVIDDAFATKLGLDSLEKLREIVTQQIQNEYDQVSRLRVKRALLDALADQAAFEVPPTLVENEFNQIWQRVDADRKADRLDEDDKGKDEDTLRADYRKIAERRVRLGLLLAEIGRVNGVQVGNDELIRAMRAEASRYPGQEQAVLDFFRQNPQAIDSLRGPIFEEKVVDFVLETAKVDDKFVSIEELNADEDVAGIA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PYRDB_BACAA
Sequence: MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPIIGMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_BLOPB
Sequence: MIDPNLLRSNLDLVAKKLARRKFILNINKFRQQESLRKILQKKTESLQTERKAKAKIIGVAKSRGENVEFLCQEAYVLGKKLTSLKLENKELKNRIKQFELSLPNIPDDQVPYGFRDQDNLEIMRWGKPGQYNFPIRDHVALGALTNGLDFSNATKLTGSRFIVMKGQIAHLHRALSQFMIDLHVKRHGYEEYYLPYLVNQDSLYGAGQLPKFYEDLFHIQHLQSGTNPYALIPTAEVPLINLVRDVILDEEELPIKMVAHTPCFRYEAGSYGHHTRGLIRMHQFDKVEMVQVVHPDKSMQILEEITSHAEQVLQLLKLPYRKILLCTGNIGFSSCKTYDLEVWLPAYNAYCEVSSCSNVGDFQARRIRARYKGRMNRKARLLHTLNASGVAIGRALAAVLENYQLEDGRVAIPSVLSPYMSDITHIN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_SHEFN
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLAGYEFIVVDTGGIDGSEEGIETKMAEQSLAAIEEADVVLFMTDARAGMTAADLAIAQHLRSRDKVTFVVANKVDGIDADSACGEFWSLGLGEVYQMAAAQGRGVTNMIDYALTPYAEAMGIVRELDEEGEQVEREYTEEEAEAEQERLQNLPIKLAIIGKPNVGKSTLINRILGEERVVVYDEPGTTRDSIYIPMSREGREYVLIDTAGVRRRSKVNEVIEKFSVIKTLKAVEDANVVLLVIDAREGIAEQDLGLLGFTLNAGRALVIAINKWDGIDQKVKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLYESIEEAYDSATRRVSTSMLTRVMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVIHGNQVKKLPDSYKRYMMNYFRRSLKVVGTPIQLRFHEGANPFEGRTEKLTVGQERRRKRAMSHIRDRTK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RSMH_BRAHW
Sequence: MDNNEELEIVHTPVMLKEVLSFIPENAKIAVDATLGEGGHTKAMLDLNLEVHSFERDSAILEIAKKRLKNYDKFHYYNNTYDKMIEELDDSIIGNVDFMLYDLGVSLFHFKKAERGFSFKDNVRLDMRLGLNEKSAYDVINGYSEEELERVLRDYGEISNARKMANVIVKERNRRKIETSRELENIIFHNTDKSQRYGKIHPATLVFQAIRIEVNDELNILEKSISNIPSILKQNGVVVVMSYHSLEDRIIKKFFKENEKTKNKDGIFKLLNNKVKLPTNEEIKSNPASRSAKMRIAQKV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_LISMO
Sequence: MKISITAPAKINLSLDALYKREDGYHEVEMVMTTIDLADRLYLERLDEDKIVLDVKAHFIPEDRRNLIYQAALLLKKRFDVKMGVRITIDKHIPVSAGLAGGSSDAAAALKGLNVIWELGLSIEELAEISSEIGSDIAFCVYGGTALATGRGEKISALPNIPGCWIVLAKPSISVSTPTIYKELQVDNVEHPDTQKMIESIKNGDLDGIFAATGNVLESVTLEKNPQVKRIKDRMLAFGAEAALMSGSGPTVFALIKQYSRAKRVYNGLRGFCEEVYMVRPWSEGENDTNINY
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.