PharMolix/UniProtQA huggingface dataset:
Protein: RL11_BACFN
Sequence: MAKEVAGLIKLQIKGGAANPSPPVGPALGSKGINIMEFCKQFNARTQDKAGKILPVIITYYADKSFDFVIKTPPVAIQLLEVAKVKSGSAEPNRKKVAEITWEQVRTIAQDKMVDLNCFTVEAAMRMVAGTARSMGIAVKGEFPVNN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RCEL_CHLAA
Sequence: MSRAKAKDPRFPDFSFTVVEGARATRVPGGRTIEEIEPEYKIKGRTTFSAIFRYDPFDFWVGPFYVGFWGFVSVIGIIFGSYFYINETILKGPYSIPQNFFAGRIDPPPPELGLGFAAPGEPGFAWQMTVLFATIAFFGWMMRQVDISMKLDMGYHVPIAFGVAFSAWLVLQVIRPIALGMWHEGFVLGIMPHLDWVSNFGYRYNNFFYNPFHAIGITGLFASTWLLACHGSLILSAAQYRGPEGGDIENVFFRDVQYYSVGESGVHRLGYIFAIGGILSADLCILLSGWPVQDWVSFWNFWNNLPFWSGV
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDSA_STAS1
Sequence: MKVRTLTAIIALIVFLPVLLKGGLILMLFSYLLAFIALKELLNMNMIKFLSIPGIISALGILIIMLPQDAGSWVNDLQLKSLIAMSFILLSYTVLSKNRFSFMDAAFCLMSIAYVGIGFMYLYETRSEGLHYILFAFLVVWLTDTGAYIFGRLMGKHKLWPVISPNKTVEGFVGGLICSLIVPLVMMIFVDFNIALWLLLIITIILSMFGQLGDLVESGFKRHFGVKDSGRILPGHGGILDRFDSFMFVLPLLNILLIQI
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRAA_YERPY
Sequence: MKYDTSDLCDIYHEEVNVVEPLFSNFGGRTSFGGKITTVKCFEDNGLLFDLLEENGLGRVLVVDGGGSVRRALINAELAELALKNEWEGIVVYGAVRQVDDLAELDIGIQAMAAIPVGAADEGVGESDIRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_ERWT9
Sequence: MSWLTPEVIDVIIAVVKALVILFVVVGCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPPFTDRVIFTLAPMIAFTSLLLAMAIVPVTSTWMGADLNIGLLFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMVDIVNSQAHLWNVIPQFLGFLTFCIAGVAVCHRHPFDQPEAEQELADGYHIEYAGMKFGLFFVGEYVGIVTVSALIVTLFFGGWQGPWLPPVIWFALKTAFFMMMFILIRAALPRPRYDQVMSFGWKVCLPLTLLNLLATAAVILYTAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KADA_SULAC
Sequence: MKIGIVTGIPGVGKSTVLAKVKEILDNQGINNKIINYGDFMLATALKLGYAKDRDEMRKLSVEKQKKLQIDAAKGIAEEARAGGEGYLFIDTHAVIRTPSGYLPGLPSYVITEINPSVIFLLEADPKIILSRQKRDTTRNRNDYSDESVILETINFARYAATASAVLAGSTVKVIVNVEGDPSIAANEIIRSMK
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_SHEHH
Sequence: MTTETLTQLEQHELFIRRHIGPESTQQQEMLNFVGAESLEDLTQQIVPGSIRLNRDLAVGSSCSEAEGMAYIREVADKNKVFKSYIGMGYYGTEVPSVIQRNVFENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASASLLDEATAAAEAMALAKRVSKAKKANIFFIADDVFPQTIDVVKTRAECFGFDIVVGPASDAVNYELFGALFQYTNRFGEISDHTALFAELKAKKAVVTVAADMMSLVLLKSPGSMGADVVFGSAQRFGVPMGFGGPHAAFFVTRDEYKRSLPGRIIGVSQDTRGNRALRMAMQTREQHIRREKANSNICTAQVLLANMASFYAVYHGPQGLKVIAERIHRLTDILAAGLTAKGLELVNSTWFDTITVKGGDVAAINARALAAQINLRIDSANDNAGSFGISLDETTTRTDVSELFDVILGSEHGLDVAALDEQIIKADSASIPSELVRTDAILTHPTFNRYHSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAATEMMPVSWAEFGNMHPFCPLDQAEGYTQLIEELSAWLVDITGYDAMCMQANSGASGEYAGLLAIRNYHISRGEGHRNVCLIPQSAHGTNPASAQLAGMKIVVTACDKAGNVDMEDLKTKAAEVADNLSCIMITYPSTHGVYEETVSEICDIIHQHGGQVYLDGANMNAQVGLTTPGSIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPFVAGHSVVKPGRESDNNGAVSAAPYGSASILPITWMYIKLLGYQGLRQSTQVALLNANYVMKKLSAHYPVLYTGRNDRVAHECIIDLRPLKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIEAMVSIRAEIAKVESGEWPVDNNPLHNAPHTLADIMDPAFDERPYTRQEAVFPTAAVKANKFWPTVNRIDDVYGDRNLMCSCAPVSDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: VPU_HV1LW
Sequence: MQPIQIAIVALVVAIIIAIVVWSIVIIEYRKILRQRKIDRLIDRLIERAEDSGNESEGEISALAEMGVEMGHHAPWDVDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: PQQC_XANOP
Sequence: MSALLSPDQLEADLRAIGARLYHDQHPFHALLHHGKLDRGQVQAWALNRFEYQRCIPLKDAAILARMEDPALRRIWRQRIVDHDGNSTTDGGIARWLHLTDALGLDRTLVESGRALLPGTRFAVQAYLQFVSEKSLLEAIASSLTELFAPNIIGQRVAGMLKHYDFVSSDALAYFEHRLTEAPRDSDFALDYVKQHADTVEKQALVKAALHFKCSVLWAQLDALHVAYVTPGIVWPDAFVPDRDASRVAA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: TYSY_STAEQ
Sequence: MYNPFDEAYHGLCEEILEIGNRRDDRTHTGTISKFGHQLRFDLTKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYVQSDDYHGPDMTDFGHRSQQDPEFNEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MORN4_RAT
Sequence: MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFSQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGLPRNEGLFENNKLLRREKCSAVVQRAQSASKSARNLTA
What is the function of this protein?
Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma.
What are the official names of this protein?
MORN repeat-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Note=Found in the cytoplasm in the absence of MYO3A and localizes at filopodial tips in the presence of MYO3A.
Protein: CYSJ_ECOL5
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGTVNEIHTSPYSKDAPLAASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPTNPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: MYO1E_RAT
Sequence: MGSKGAYRYHWQSHNVKHSGVDDMVLLSKITESSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQYENPPHIYALADSMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYVSRVSGGGPKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASPEQKQSLGITSMDYYYYLSLSGSYKVDDIDDKRDFQETLHAMNVIGIFSEEQTLVLQIVAGILHLGNINFKEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIESKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRVFQKFLQRYAILTKATWPVWRGDEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKTWRKFVARKKYVQMREDASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADIVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEVERILSVSLSTMQDDIFILHEQEYDSLLESVFKTEFLSLLTKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFYQGFGDLAILKPSNKVLQVSIGPGLPKNARPTRRNTVSSRGYSGGTNNNYPMRAAPAPPGCHRNGLTRNQFVHPPRASGNQRSNQKSLYTSMARPPLPRQQSTGSDRLSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDVIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments.  Binds to membranes containing anionic phospholipids via its tail domain.  Involved in clathrin-mediated endocytosis and intracellular movement of clathrin-coated ve (By similarity)sicles.  Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function (By similarity).  In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14 (By similarity).
What are the official names of this protein?
Unconventional myosin-Ie, Myosin heavy chain myr 3, Unconventional myosin 1E.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin- coated vesicle. Cell junction. Note=In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles (By similarity). Detected in cytoplasmic punctae. Colocalizes with F-actin.
Protein: TTCA_CITK8
Sequence: MSQNQDISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPVNFSLVAVNLDQKQPGFPEHILPEYLENLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIERFSEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLSDINLFDFKGINHDSDVVDGGDLAFDREEIPLQPAGWQPEEDDNQLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGP_ECOLI
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.  Activates transcription of several genes, including argO, lysP, lysC, asd, dapB, dapD, lysA, gdhA and argK.  Acts by binding directly to their promoter or control region (PubMed:10600368, PubMed:15150242, PubMed:17504942, PubMed:21441513, PubMed:21890697).  ArgP dimer by itself is able to bind the argO promoter-operator region to form a binary complex, but the formation of a ternary complex with RNA polymerase is greatly stimulated only in presence of a coeffector.  Both arginine and lysine are coeffectors at the argO promoter, but only arginine is competent to activate transcription.  Lysine has repressive effects (PubMed:15150242, PubMed:17504942).  ArgP also mediates lysine repression of dapB, and gdhA in vivo, but via an alternative mechanism: ArgP binding is directly reduced upon the addition of lysine (PubMed:21890697).  Binds in vitro to the promoter region of dnaA and to the upstream region of the nrd promoter, but these genes are probably not regulated by ArgP in vivo (PubMed:9254708, PubMed:9819053, PubMed:21890697).  In vitro, binds also to the three 13-mers located in the origin region (oriC) and blocks the initiation of replication (PubMed:1733927).
What are the official names of this protein?
HTH-type transcriptional regulator ArgP, Inhibitor of chromosome initiation, OriC replication inhibitor.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SYS_PHEZH
Sequence: MHDIRAIRETPELYEKAWAAKGSPGKVAEILKLDEALRAAQTALQAAQAERNEASKKIGQAKAQKDEAEATRLMAHVETLKKALEEQGEVERSAGEALRALLAGLPNIPAAEVPDGADEHDNVEVRRWGEPRAIAAPKDHATLGEAMGLMDFEAAARMSGARFVVLKGQLARLERALGQFMLDLQTQEHGYTEVNPPLLVNDAAAYGTDKLPKFAEDLFQTTDGRWLIPTAEVPLTSLVMGQIVAEEELPLRYTALTPCFRSEAGASGRDTRGMIRQHQFNKVELVSITTPEQSADEHERMVGCAEAVLKRLELPFRTMLLCRGDMGFGARKTYDLEVWLPSQEKYREISSCSNTGDFQARRMDARAKKAGEKGTRYVHTLNGSGLAVGRTLVAVLENYQDEGGRIAIPEALRPYMPGMTHIGGAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLH12_CAEEL
Sequence: MAKKPRVTKLNTDRRSRANERERQRVSEMNGMFDVLLNLLPPSHFKTRLSRVQILREATSYIIRLHNFLIESSNSDIDAITVFPHIFNGERKSNKDAIRRPMKLKQGGGVAAFISRHELPPLQLPNPVIPILKPTSVPVWPQTNVYIAYF
What is the function of this protein?
Transcription factor which binds the E box motif 5'-GCAGGTG-3' (PubMed:17588558).  Involved in migration of the gonadal leader cells; distal tip cells (DTCs) in hermaphrodites, and linker cells in males (PubMed:25982859, PubMed:17588558).  Positively regulates expression of alpha integrin ina-1 and ADAMTS protease gon-1 (PubMed:25982859, PubMed:17588558).
What are the official names of this protein?
Helix-loop-helix protein hlh-12.
What are the subcellular locations of this protein?
Nucleus.
Protein: YPT35_DEBHA
Sequence: MTASNRRGSTHRNSVTQLNKVLPVPIQLEDETSSGHFNSTSHITDVLVGDYHVIQGEGGSSYVVWSIRIIVDDSVYSSMVIYKRYSDIQRFREALLEHYPNTEIPPLPPKDNFSFQRLSMSDYWLENRRKGLQWFMTNVMLNPKHQHSPVITHFILN
What is the function of this protein?
Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
What are the official names of this protein?
Endosomal/vacuolar adapter protein YPT35, PX domain-containing protein YPT35.
What is the protein family that this protein belongs to?
Belongs to the YPT35 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: RL34_BRUME
Sequence: MKRTYQPSKIVRKRRHGFRARMATTGGRKVLAARRTRGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DRD5L_TAKRU
Sequence: MENFYNETEPTEPRGGVDPLRVVTAAEDVPAPVGGVSVRALTGCVLCALIVSTLLGNTLVCAAVIKFRHLRSKVTNAFVVSLAVSDLFVAVLVMPWRAVSEVAGVWLFGRFCDTWVAFDIMCSTASILNLCVISMDRYWAISNPFRYERRMTRRFAFLMIAVAWTLSVLISFIPVQLNWHRADNNSSAHEQGDCNASLNRTYAISSSLISFYIPVLIMVGTYTRIFRIAQTQIRRISSLERAAGQRAQNQSHRASTHDESALKTSFKRETKVLKTLSVIMGVFVFCWLPFFVLNCVVPFCDVDKVGEPPCVSDTTFNIFVWFGWANSSLNPVIYAFNADFRKAFTTILGCSKFCSSSAVQAVDFSNELVSYHHDTTLQKEPVPGPGAHRLVAPLPQNRGDAGPNFDKVSVVSDDSRADRNLLLPAILQCDCEAEISLDMVPFGSSGPADSFLIPGQIQDLGDL
What is the function of this protein?
Receptor for dopamine.
What are the official names of this protein?
D(5)-like dopamine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAZ_GEOSL
Sequence: MFRGIYETTIDAKGRTSLPAKFREVLVDVHGDDRFVITNSAPVDLGAGTFSSGLLIFPYAKWVEFEENFRSSKGLTSAQRNSIMRTIISPAVECCADKLGRLLIPPHLRKGAALERDILFVGVMDKIEVWSQAEREKVRIQDLKNFPSDSETVAELGL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RIMO_HELPH
Sequence: MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKSADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEVENLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIKAIDKQQALKSARILYLYPSSTTLELIGAIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENEGEFEELSAFLDEFRFDRLNIFAFSAEENTHAYSLEKVPKKTINARIKALNKIALKHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVDGEILINDSELATPLQPGHYTIVPSVFKDNILLAKVLSPF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIOX_HUMAN
Sequence: MKVTVGPDPSLVYRPDVDPEVAKDKASFRNYTSGPLLDRVFTTYKLMHTHQTVDFVRSKHAQFGGFSYKKMTVMEAVDLLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALFGEPQWAVVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQDLAMLPWVREFNKFDLYTKCPDLPDVDKLRPYYQGLIDKYCPGILSW
What are the official names of this protein?
Inositol oxygenase, Aldehyde reductase-like 6, Kidney-specific protein 32, Myo-inositol oxygenase, MI oxygenase, Renal-specific oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_PHOV8
Sequence: MIELIPAIDIIDGKCVRLSQGDYNTQKVYNENPVEVAKEFEAHGIHRLHIVDLDGAVSRHVVNYRVLDQIASRTSLVIDFGGGIKTDEDLVIAFDNGAQMVTLGSVAVKNPGLFKKWLEQYGNEKIILGADVKENKISVNGWKEESQQQLIPFLKDYTKEGVFKVLCTDISRDGMLQGPSVELYQQILKEFPNMHLIASGGVSCIQDIIDLEIAKVPAVVFGKALYEGKITLKDLNRFM
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_MALP2
Sequence: MKKLIIANWKMFKTLNDIKTFKEEFDKNIKNVKVNADYSVGVPSIYLNQAKEILKGIKVIAQDAHFKNEGAYTGNISWSQLKDCGIDGSIIGHSERRQMFNETDETVNLKTISLVENNMQAVVCVGETLEEYEANKSFDVVWNQTKKALANVSEAQLKNVVIAYEPVWAIGTGKVPTGKEVDDLIQKVRDELSKLYSKQAVESLVVLYGGSVNDKNAEEFFKQKNINGALVGSFCLKAENFVKLIELGGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL331_BACVZ
Sequence: MRVNITLACTECGERNYISKKNKRNNPDRVEFKKYCPRDKKSTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.