PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_ALISL
Sequence: MQQLTIAIDAMGGDFGPQVTVPAVVQALSQFPELKVTVVGDRDAISTQLTHLNYTLNPRFSIVHSDSVIGNNTQPSKALRHSRGSSMRMALDLVASKDVDACISAGNTGALMGLSRFTLKLLPGVERPALISPLPTKNNQRTWMLDLGANVSCDAETLFQFAVMGSELAEQSIGRKAKVALLNIGEEEIKGNDQIKRCAEMLNQCQNIEFIGYIEGDKLYQGIADVVVCDGFVGNVCLKTSEGVAHLFLDQLKSQLLTSKFKQILAKWLFGDVISSLKGLNPDQYNGASLIGLRGIVVKSHGSADISAFNNAIKEAVHEIKRQIPNRISDRLEAVLLERHY
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FOLD_AZOVD
Sequence: MTAKLIDGKAIAASLRQQIAQCVAERRQQGLRAPGLAVILVGTDPASQVYVSHKRKDCEEVGFHSRAYDLPASTTQGELLSLIDRLNEDSAIDGILVQLPLPVHLDASLLLERIRPDKDVDGFHPYNIGRLAQRMPLLRPCTPKGIMTLLQSTGANLYGLDATVVGASNIVGRPMALELLLAGCTVTVTHRFTRNLAEHVSRADLVIAAAGKPGLVKGEWIKPGAIVIDVGINRLDDGRLVGDVEFSSAAARAEWITPVPGGVGPMTRACLLENTLHAAEQLHR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: NDK_BRUAB
Sequence: MAIERTFSMIKPDATRRNLTGAIIAKLEEAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEFMSSGPTVVQVLEGENAIAKNREVMGATNPANADEGTIRKTFALSIGENSVHGSDAPETAAEEIAYWFSGTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_CHLAD
Sequence: MTIATERYSRSQANFAAAQAVIPGGVNSPVRAFRGVGGSPIFFERGQGAHIWDVDGNRYIDYVLSWGPLLLGHAHPAVVNAIATQAQRGTSFGAPTELETDLARLVLDLVPSIEQIRFVNSGTEATMSALRLARAATGRRLIVKFNGCYHGHADMLLVQAGSGVATLGLPDSPGVPPTVAADTITIEYNDLDAAADLFARRGSEIAAVIVEPIAANMGFVLPKPGFLSGLRELTQQHGAIFILDEVMTGFRVAPGGAQALWNLDPDLTCLGKVIGGGLPVGAYAGKRHLMQLVAPAGPMYQAGTLSGNPLAMIAGLTTLRTAFTDDNTAFQRAVTLTTRLANGLRELGERYRIPLQVGNVGTMFGCYFLRHADAQITNYVEAKANADTQRYARFFWAMADRGIYLAPSQFEAGFVSTAHTDADIDQTLTAVEEAFAQL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SHIB3
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DNAK_CHLPM
Sequence: MGKIIGIDLGTTNSCVAVMQGTQPTVIENSEGNRTTPSMVAFTKNGDRLVGQAAKRQAITNPTNTIFSIKRFVGRKFDEVPNEKKIAPYAVVNEGGEARVKINDKTYSPQEISAMILQKMKQTAEDFLGEKVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKKTSSEKVAVFDLGGGTFDISILELGDGVFEVKSTDGDTHLGGDDFDQKIIDFLADEFKKQEGIDLRNDPIALQRLKEAGEKAKIELSSRTDTEINLPFITATQEGPKHLVINLTRAKFEGICADLFAKILEPCQRAVKNSKVPMKEIDEIVLVGGSTRIPKVQALVKDFFGKEPNKSVNPDEVVAVGAAIQGGVLKGDVTDVLLLDVTPLSLGIETLGGVMTKLIDANTTIPTKKQEVFSTAGDNQTSVEVHVLQGERSMATDNKTLGRFHLGDIPPAPRGLPQIEVAFDIDSNGILHVSAKDKATGKEQSIKIEASSKLTDAEIEKMKEDAKAHAEEDKKLKEEIDIKNSADALIFSTEKQLEELGDKIPADKRPAIDGALEKLKDAHKNGTTETIQSGMEELSKVWSEVAADLYKEEPQGNPEGGSAPEGEKKGDDGSVENAEYEVIDGDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NADD_IDILO
Sequence: MIRAIFGGTFDPIHNGHLQTAAALVKELGISTLALMPSAVPPHRPQPDASPEQRLDMVKLASQYHKAFTVEDWELRQDRPSFTANTLSEFKTQFPDDTLLFVMGMDSLMSLHRWHHWCQLIECAHLVVMPRAGVPFNPKNDELKEFISVHLTRDKNALNTQSQGLLYIAETPMVDVSATELRKQLQQREKNLPLPSNVYNYIRQHQLYL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: NIT2A_XENLA
Sequence: MAKFKLSLVQFLVSPVKSDNLNRACKLIKEAAQKGAQIVALPECFNSPYGTTYFPEYAEKIPGESTELLSQVAKECGIYLIGGSIPEEDCGKLYNTCAVFGPDGTLLVKHRKIHLFDIDVPGKIRFQESETLSPGDSFSVFDTPYCKVGVGICYDIRFAELAQIYANKGCQLLVYPGAFNMTTGPAHWELLQRARALDNQVYVATASPARDEKASYVAWGHSTIVSPWGEVVAKAGSEETVLSAEIDLQYLAEIREQIPIRRQRRRDLYNVEEKRN
What is the function of this protein?
Has omega-amidase activity.  The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively.
What are the official names of this protein?
Omega-amidase NIT2-A, Nitrilase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANM2_MOUSE
Sequence: MEAPGEGPCSESQVIPVLEEDPVDYGCEMQLLQDGAQLQLQLQPEEFVAIADYTATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRPKSNHILKPEDCLSEPCTILQLDMRTVQVPDLETMRGELRFDIQKAGTLHGFTAWFSVYFQSLEEGQPQQVVSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVHGFCCVTKKSGMEKAHVCLSELGCHVRTRSHVSTELETGSFRSGGDS
What is the function of this protein?
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4.  May inhibit NF-kappa-B transcription, and promote apoptosis.  Represses E2F1 transcriptional activity (in a RB1-dependent manner).  Has a negative regulation effect on G1 to S transition of mitotic cell cycle.  Involved in growth regulation.  Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation.  Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation.  Enhances PGR, PPARG, RARA-mediated transactivation.
What are the official names of this protein?
Protein arginine N-methyltransferase 2, Histone-arginine N-methyltransferase PRMT2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from the cytoplasm to the nucleus, after hormone exposure.
Protein: PYRE_HERAR
Sequence: MNNLRQEFIKFSVDTGVLRFGEFVTKAGRTSPYFFNAGLFNQGGTLARLADFYAQTLIDSGVEFDMLFGPAYKGITLASATAVALANKGRDVPFAFNRKEAKDHGEGGTMVGAKLQGRVVIIDDVISAGTSVRESVDMIRAAGATPCAVLIALDRMERSGADDALSAYSAVQEVSNTYGMPVISIGNLSDLFEYLSNAGADSEQAQYRDAVSAYRKRYGVT
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LYSM_BOVIN
Sequence: MKALLIVGLLLLSVAVQGKKFQRCELARTLKKLGLDGYRGVSLANWVCLARWESNYNTRATNYNRGDKSTDYGIFQINSRWWCNDGKTPKAVNACRIPCSALLKDDITQAVACAKRVVRDPQGIKAWVAWRNKCQNRDLRSYVQGCRV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, milk isozyme, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: CAIB_ECOSE
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLSTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_ACICJ
Sequence: MLSPKRTKFRKAHKGRIHGTAKGNTQLNFGQFGLKALEPERITARQIESARRAITRQMKRAGRVWIRIFPDLPVSTKPAEVRMGSGKGAPEYWVARVQPGRIMFEIDGVAEGIAREALKLGAAKLPIKTKIVTRIGEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YEEC_BACSU
Sequence: MASNRYHSINEIMESQLFYQITTPPKKTQKAQYDPEVEKFLEIIEFVKENGREPQKVPTDLTERSLASRLIGIRKDPDRMEYLKEYDEIGLLEVRSKELTIPKISSIDDILKSGLSALLGDNLNNDITRSIFDTSSLQKVTTMPEYVAKRKKIKDFGKFEELFKKCHKEITEGKRKILTFKNEQDIQSNSFYILKGVLLYVEDVGERKKAKGKTNARLRCIFENGTESDMLLRSLSAELYKHGRRVTDNEDTLLDNVREDDVSTGFIYVLKSLSTDPQISSIKNLYKIGFTTGSVENRIRNAENQSTYLYAPVEIVTTYQVFNMNASKFETAIHHALANNNLDVSILGANGKMLVPKEWFVVTLEDLQAVIDEIVMMVHLYD
What are the official names of this protein?
Uncharacterized protein YeeC.
Protein: KAD_RHIME
Sequence: MRLIFLGPPGAGKGTQAKLLTERYGIPQLSTGDMLRTAVAQATEVGKRAKAVMDAGQLVSDEIVNEIVSDRIDSADCARGFILDGYPRTVPQAVALDRMLEEKGLKLDAVIELKVDEAALVRRMENRVTETVAAGGTVRSDDNPEAFRRRLQEYREKTAPLSEHYARTGRLKTVDGMADVHTVTAEIEKILA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RACL_DICDI
Sequence: MQYIKMVICGDGAVGKTSLLIAFASGEFPRDYQPTVFDNFSTLYMFQNKAYNLGLFDTAGQEDFDRLRPLGYNDTDLFLICYSVINPPSYANVYDKWYSEIKLYTGSEIPLILVGTQNDLRHDKATRETLALKQQAPISYEEGMMMRKRIGAKAFTECSVVSGKNVKQVFEEAIKVYQDRQIEISKSKEKNNCIIL
What are the official names of this protein?
Rho-related protein racL.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LPP1_SALTI
Sequence: MNRTKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNQATKYRK
What is the function of this protein?
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes.  The only protein known to be covalently linked to the peptidoglycan network (PGN).  Also non-covalently binds the PGN.  The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
What are the official names of this protein?
Major outer membrane lipoprotein Lpp 1, Braun lipoprotein 1, BLP 1, Murein lipoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the Lpp family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Secreted, cell wall; Peptidoglycan-anchor. Note=Attached via its lipidated N- terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.
Protein: ARGJ_PENRW
Sequence: MATSLARMLKGQVRCYSAPLDMAIPASKQRYIPTTGTYPQGFQVSGTHVGVKASNTRFPDLALIASDTPCSAAAVFTTNKFQAAPVQVSRKTLQSRKGDGIRAVVINSGCANAVTGKGGLEDAVQMGRKVDECSGVENDSSLVMSTGVIGQRLPISKILDRIPTAHSTLASTHEAWLNTARAICTTDTFPKLLSRTFTLPSSPDRSYRLAGMTKGAGMIHPNMATLLGVLCTDAAVEPAALQSILKHAVSRSFNSISIDGDTSTNDTIAVLANGAAGGETVRAPGASASADYTALQGVVTDFAQELSQLVVRDGEGATKFVTVRVRNSPDYESGRMIASTIARSPLVKTALYGKDANWGRILCAVGYTQGVAEGTVVPERTSVSFRPVDGSEVLKLLVNGEPETVDEQRASVILQNEDLEIEVDLGGGEQGAAGCGGEDAVYWFCDFSHECIPAFAVDIIESREISGLKAFGSENAYIYEEEPLK
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ATPB_BUCAP
Sequence: MIATGKIIQIIGAVVDVEFDQNSVPKIYNALEVKNKKIQLILEVQQQLGAGIVRTIAMGSTNGLKRGLIVIDLGHYIKVPVGQATLGRIINVLGKTIDNKGPLKNLDNSKLEYWEIHRSAPSYQEQASSQEILETGIKVIDLICPFSKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFTGVGERTREGNDFYHEMKDSKVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGLLQERITSTKEGSITSVQAVYVPADDLTDPSPATTFAHLDSTVTLSRQIAALGIYPAIDPLNSTSRQLDPYIVGDEHYDTARGVQSILQRYQELKDIIAILGMDELSQEDKILVSRARKIQRFLSQPFFVAEVFTGFPGKYVSLKDNIRAFKGIIGGEFDNLPEQAFYMVGTIEEVIKKAKLL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PGLRA_ASPAW
Sequence: MPSAKPLFCLATLAGAALAAPAPSRATDFNKRSTCTFTDAATASESKTSCSDIVLKDITVPAGETLNLKDLNDGTTVTFEGTTTWEYEEWDGPLLRISGKDITVTQSSDAVLNGNGAKWWDGEGTNGGKTKPKFFYAHDLDDSKISGLYIKNTPVQAISVESDNLVIEDVTIDNSDGDSEGGHNTDGFDISESTYITITGATVKNQGDCVAINSGENIYFSGGTCSGGHGLSIGSVGGRDDNTVKNVTFIDSTVSDSENGVRIKTVYDATGTVEDITYSNIQLSGISDYGIVIEQDYENGDPTGTPSNGVTISDVTLEDITGSVDSDAVEIYILCGDGSCTDWTMSGIDITGGETSSDCENVPSGASCSQ
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase A, Pectinase A, Polygalacturonase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXA_ECOBW
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTH_SHEWM
Sequence: MTTPHSPKTIDELMSRANDMAGLTLGQLADSHGFITPANLKRDKGWVGQLIEHELGALAGSRPEPDFLHLGIELKTIPVDKNGKPIETTYVTVAPLIDIQGLTWETSVVCHKLQTVLWIPIQGDRDIPVSQRQIGSPILWRPNEEELALLKQDWEEIMEFIALGQVKQLTARHGEVLQLRPKGANSRSVTQSIGPNGSTQMTNPRGFYLKIPFTQSILSRAFGIYTQATSR
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_NEIM0
Sequence: MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAADYPGKAAFYQLGK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL14_STRPI
Sequence: MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPVARELREGGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: BARX2_HUMAN
Sequence: MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS
What is the function of this protein?
Transcription factor.  Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'.  May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system.  May be involved in controlling adhesive processes in keratinizing epithelia (By similarity).
What are the official names of this protein?
Homeobox protein BarH-like 2.
What is the protein family that this protein belongs to?
Belongs to the BAR homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFB_CERS1
Sequence: MIEAAVSMSALGLGLGLLLGVAARRFHVESPPILDAIEGILPGTNCGACGYPGCRGLAEAMSEGAAPVTACAPGGRDVALALAAIVETDGGGGAVPGMAEAEPTVAFIFEDHCTGCMRCFKRCPTDAIIGANRQIHTVVTDACIGCNACIEACPTEAIVARVKPKTLKSWYWDKPRTAFEARDTEVAA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOY_BACP2
Sequence: MIYKVFFQASTTEVPVREHTDSLYVEAVSERDVRDKLKKHSYNIEFIQPVDGAFLDYERESENFKVLEL
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: CSRA_ACIBC
Sequence: MLILTRRVGETLMIGDQVSVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQHERAMHEHLQHLDQDYQVSYEDDNYAQKNFNR
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_CALS4
Sequence: MRVKAEIMDEKAIDRALIRIAHEIVERNKGIEDVVLVGIKTRGVPLAKRIARYISRIEGKEPPVGSLDITLYRDDLTTDLEQPVVKKKDIGVDVANKIVVLVDDVIYTGRTVRAAMDAIIDLGRPKAIQLAELVDRGHRELPIRPDYVGKNVPTSRSEIIQVMLEEVDGVNKVVITEK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: GPDA_ECOBW
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.