PharMolix/UniProtQA huggingface dataset:
Protein: Y3560_PSET1
Sequence: MGRAFEVRKSSMAKTANAKTKVNSKYGKEIYVAAKNGEPDPDVNQTLRRLIEKAKKDQVPAHVIEKAIEKAAGGAGEDYSTARYEGYGPGNCMVIVDCLTDNPNRTIKDVRLPFTKTDSKIGTPGCVAHMFDHFAVLGFSGDDDEVVLEALMMADVDVTDVEVEDGKVSVFAPHTEYFKAKTALEEAFEGINFEVDEITFVPQVHIEITDEEVIANFDKFITMLEDCDDVQNIYHNAIIKN
What are the official names of this protein?
Probable transcriptional regulatory protein PSHAb0060.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_ERWT9
Sequence: MKRLRFNYLLIGLITVLLALALWPSIPWYGGSTDRIAQIKSRGELRISTINSPLTYYTVNQSPAGMDYELAKRFADYLGVRLVVTVRPNLADLFDDLADDKADILAAGLIYNRERLKRFRAGPSYYSVSQQLVYRIGTSRPKNLGDLKGRLTVASGSAYLSSLREIKDRQYPDLDWAVSTDRTPDGLLQAVADGKIDYTIADSVSIGLMQRIHPQLTVAFDITEEEAVTWYTQQEANDSLNAAMLDFFSKMSEEGVIARLDEKYLGHVGTFDYVDTRTFLRSIDETLPDIRRLFEKYAKKIDWRLLAAISYQESHWDPLATSPTGVRGMMMLTRSTADSLNVSDRTDAEQSIRGGSEYMTHMMEKVPSGVPEDERIWFALAAYNMGYAHMLDARKLTEKQKGDPNSWADVKVRLPMLSQKRYYSQTTYGYARGHEAYAYVENIRKYQLSLVGYLQDRERKLAQKMAAEAELRQAYPAVEPDAALNPVSALPLP
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: TRMD_UREU1
Sequence: MKISILSLFPELYETWINHSIISNAIKNNQVTIEIINFRLYTNDKHKKVDDYQYGGGAGMVLMIEPIVSAIRAIRTPNSYVILTTPKGQVFNQELANEFVSKYDHIIIIAGHYEGFDERINYYVDAQYSIGDFVLTGGELPSMVISDAVIRLLDGVISSSSLESESFNNYLLDYPVYTRPVVFEGHQVPDVLLSGHHKNIADFRKQQQEMITKKNRPDLYQKYLNSKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1475_HAEIG
Sequence: MIQKLFLLVRSLVILSIMLYLGNLIAYYIPSGVPGSIWGLLLLFLGLTTRVIHLNWIYLGASLLIRFMAVLFVPVSVGIIKYSDLLIEQINILLVPNIVSTCVTLLVIGFLGHYLYQMQSFTHKRKKVIKRRENQVKQAN
What are the official names of this protein?
UPF0299 membrane protein CGSHiGG_01475.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNAT4_ARATH
Sequence: MRSTPLGTTAVSPASIKHNSYGYGRFVSSSGVSNFSIHRRRRHSSFSISQAPSQINSGACNASQIVDLFPAVSPEIVVREARLEDCWEVAETHCSSFFPGYSFPLDVVLRVDRLMAMVMGFSIPPGCQRTCLVAVIGSSVDETICFGSDDFKIGAFDAKISLNKGYVAGILTVDTVADYLPRKGPLRQRRTGIAYVSNVAVRENFRRKGIAKRLIWKAEALAKNWGCRAIGLHCDLNNLGATKLYKDQGFRSIKIPEGATWPQPKTSPDTRFTFMMKLVNNNNTQALEQFR
What is the function of this protein?
Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a large spectrum of modified N-termini, including methionine, alanine, serine, threonine and to a lower extent glycine and valine as substrates, and epsilon-lysine acetylation (KA) of several plastid proteins.
What are the official names of this protein?
GCN5-related N-acetyltransferase 4, chloroplastic, N-alpha-acetyltransferase 70, AtNAA70.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: MAD2_MAIZE
Sequence: MASRSASKDIITLRGSAAIVSEFFGYAANSILYNRAVYPEESFSKVKKYGLTMLLTQDEGVKNFIASLTSQLSEWLEAGKLQRIVLVIMSKATSEVLERWNFNIVTDAEVVEKGAIKEKSDKEIMREIQAIMRQIASCITYLPCLDEPCVFDVLAYTDTDVDAPGTWVESDAKLIDNPQMVKLHSFDTKIHKVDTLVSYKKDEWDEEE
What is the function of this protein?
Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete.  It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate (By similarity).
What are the official names of this protein?
Mitotic spindle checkpoint protein MAD2.
What is the protein family that this protein belongs to?
Belongs to the MAD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSY_SHEHH
Sequence: MTLTVLTIVIIVGAYLAGSVSSAVLVCKIRGLPDPRTQGSGNPGATNVLRIGGASSAALVLFCDMLKGAAPAYLAFRLGVDPIALGVIAIAACLGHIFPIFFGFKGGKGVATAFGAMAPIGHDLALCLLASWIVLVLVTRYSSFAAICTALLAPVYTWWLDDRFTIPVAMLSTLIVIRHKDNIKRLLKGEESKVSRKKT
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXK_SHIFL
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRAFQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: XGPT_CERS5
Sequence: MKERLPHEKGFHVSWDQIHRDSRALAWRLDGQGPDNGAWRAVVGITRGGLVPAMIVSRELDIRTVDTISVKSYNWQEQQPPSVIKAPQAELMGDGHGILIVDDLVDSGKTLELVRTLYPRAHFATVYAKPSGRPMVDTYITEVSQDTWIFFPWDMALQYVEPYRGRD
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FAS_HUMAN
Sequence: MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
What is the function of this protein?
(Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication.
What are the official names of this protein?
Fatty acid synthase, Type I fatty acid synthase.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: RR19_HELAN
Sequence: MTRSLKKNPFVANHLLKKINKLNTKEEKEIIITWSRASTIIPIMVGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCN2_RAT
Sequence: MLASVAGPVSLALVLLLCTRPATGQDCSAQCQCAAEAAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCVFGGSVYRSGESFQSSCKYQCTCLDGAVGCVPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDRTVVGPALAAYRLEDTFGPDPTMMRANCLVQTTEWSACSKTCGMGISTRVTNDNTFCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKIAKPVKFELSGCTSVKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEIMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
What is the function of this protein?
Major connective tissue mitoattractant secreted by vascular endothelial cells.  Promotes proliferation and differentiation of chondrocytes (By similarity).  Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity).  Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
What are the official names of this protein?
CCN family member 2, Cellular communication network factor 2, Connective tissue growth factor, Connective tissue growth-related protein.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: Y2558_MYCTU
Sequence: MPGSAGWRKVFGGTGGATGALPRHGRGSIVYARSTTIEAQPLSVDIGIAHVRDVVMPALQEIDGCVGVSLLVDRQSGRCIATSAWETLEAMRASVERVAPIRDRAALMFAGSARVEEWDIALLHRDHPSHEGACVRATWLKVVPDQLGRSLEFYRTSVLPELESLDGFCSASLMVDHPACRRAVSCSTFDSMDAMARNRDRASELRSRRVRELGAEVLDVAEFELAIAHLRVPELV
What are the official names of this protein?
Uncharacterized protein Rv2558.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2557.
Protein: NFUA_SHESH
Sequence: MITISDAAQAHFVTLLADQPEGTHIRVFVISPGTATAECGVSYCPPDAVEADDMEFEFNGFNAMVDEKSAPFLEEASIDFVTDQLGSQLTLKAPNAKMRKVASDAPLSERIDYVIQSEINPQLASHGGNIMLVEVTEEGTAILQFGGGCNGCSMVDVTLKDGIETQLLEKFPGELTGVKDVTEHQHGDHSYQ
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: PUR7_METAC
Sequence: MKREQLYSGKAKTIYATDNPDTLIAEFRNSLTAFNGEKKGEMEKKGYYNAQISKKIFEMLEASGIKTHFVSMLSDIEMLVKKVEIIKIEVIVRNIAAGSITKKYPMKEGTIFESPVLVFDFKSDEYGDPMLNDDIAVALGIATREELATLRKLALRINELLVPYLDEKGILLPDFKLEFGRRDGEIILSDEISCDTCRFWDKKTGQSMDKDVFRFDKGDISKAYEEVARRIVPEIFE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYC_CORK4
Sequence: MTLRIFDSASRQLRDFVPLREGRASVYLCGATVQSAPHIGHLRSGVAFDILRNWLTYMGLDVAFIRNVTDIDDKILNKAAEHNRPWWEWAATYEREFQWAYDQLGVTPPSLEPHATGHVPEMIEYMQRIIDAGHGYAVDGNVYLSPMSLPDYGSLSGQKLDEMDQGESAGTGKRDPRDFTLWKAAKPGEPSWDTPWGRGRPGWHLECTTMATKYLGAEFDIHAGGLDLKFPHHENEIAQAHAAGDGFARYWMHNGWVTMAGEKMSKSLGNVLSVPNLLQIVRPVELRYYLGSAHYRSMLEFSEDALREAAAGYRRLEKFVHAASSVAGKNDRTLGRSEVTDAFTDAMNDDIGVPAALAEVHKVVRSSNSRLDAARRGDSDAVESVVSAGEQVRAMLGVLGVDPLDEKWQEIAAESGAEHDALDTLVRAELDIRAKARAEKDWATADAVRDRLAAAGIVVTDTPSGAEWELSEQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_MYCTA
Sequence: MTEFHSGFVCLVGRPNTGKSTLTNALVGAKVAITSTRPQTTRHAIRGIVHSDDFQIILVDTPGLHRPRTLLGKRLNDLVRETYAAVDVIGLCIPADEAIGPGDRWIVEQLRSTGPANTTLVVIVTKIDKVPKEKVVAQLVAVSELVTNAAEIVPVSAMTGDRVDLLIDVLAAALPAGPAYYPDGELTDEPEEVLMAELIREAALQGVRDELPHSLAVVIDEVSPREGRDDLIDVHAALYVERDSQKGIVIGKGGARLREVGTAARSQIENLLGTKVYLDLRVKVAKNWQRDPKQLGRLGF
What is the function of this protein?
Exhibits GTPase activity (By similarity).  Binds RNA but is probably not involved in ribosome assembly in mycobacteria (PubMed:35917161).
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: TSAD_TREPA
Sequence: MNVLGIETSCDETAVAIVKDGTHVCSNVVATQIPFHAPYRGIVPELASRKHIEWILPTVKEALARAQLTLADIDGIAVTHAPGLTGSLLVGLTFAKTLAWSMHLPFIAVNHLHAHFCAAHVEHDLAYPYVGLLASGGHALVCVVHDFDQVEALGATIDDAPGEAFDKVAAFYGFGYPGGKVIETLAEQGDARAARFPLPHFHGKGHRYDVSYSGLKTAVIHQLDHFWNKEYERTAQNIAAAFQACAINILLRPLARALQDTGLPTAVVCGGVAANSLLRKSVADWKHARCVFPSREYCTDNAVMVAALGYRYLIRGDRSFYGVTERSRIAHFSKRGGDRLAAQRSAASQPLF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YYBB_BACSU
Sequence: MNLRQLSEHVFQCEFELDVPLRIPVHTWFIKDGDDVYIVDTGIERFADAQIRAALAIGNPKAILLTHGHSDHIGGASKWLERFDIPIFAHQKELKYINGEEPYPNKNEVENTGVAHIVQPLTEQTLAHLPLKYYLTPGHSPGHVVYYHKIDRTLLTGDLFITSKEDLHPPIRRFSVDINENIDSGSIIDQIKPTLICSSHGEEILYNEELYKNYVVRYRD
What are the official names of this protein?
Probable metallo-hydrolase YybB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: ARGR_YERP3
Sequence: MRNPAKQEDLIKAFKALLKEEKFSSQGEIVLALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDVDYNDSVVVINTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKQLHEAILRLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y044_NPVOP
Sequence: MAATTLTGDDGHFGAARRAGGCVAFTVRRYNRHVVGFSGIRARMLEKLRDAGRLLPADTKCALHTVPAACARCRRSLTLTPAVSCLPCGHSCLCTDCDQLFANVCFECKSAVQFKLRFIK
What are the official names of this protein?
Uncharacterized 13.0 kDa protein.
Protein: TBCK_CHICK
Sequence: MFPLRDTEMGASTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDITRGKHERLVVAAEHCENSLEDLLREGKLVSSSRILCIAYEVLQGLQYMNKHGMVHRALSPRNILLDRKGHVKLAKFGLYHMTAQGVDVDFPIGYPSYLAPEVIAQGMVKPSDHTQCEKPLPSGPKSDLWSLGIILFELCVGRKLFQTLEIAERLKFVITLGYVDDIVTVLAEEHGCLDIIKDLSENVITLLKKCLTFQPSKRPTPEELMHDHLFSEVSLTYPPFHKPAGLFSSSPRCADLTLPEDISQLCKDEDNDYLAERSIEEVYYLWCLAGGDLEKELVNKEIIRSKPPVCTLPNFVLEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSTLPHSNSSSELSAAANLPLIIRERDTEYQLNRIVLFDRLLKAYPYKKNQIWKEARVDIPPLLRGITWAALLGVEGAIQAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESINLFRWTPKSATYRQYAQPPRQANESNGTRSSMSCFSVDYQEAPRGDLSRDSIKLDDLKAEVSPRISAEDLIDLCELTGPSHSKTPIKKTKSSKPKLLVVDIRNSEDFNRGHISGSINVPFASAFTAEGDLIQCPATATLQSFKGRVVVIVGNAVKNTAAFAAHLVKSKYPRVCILDGGINKIKPTGLLTVPSPQI
What is the function of this protein?
Involved in the modulation of mTOR signaling and expression of mTOR complex components.  Involved in the regulation of cell proliferation and growth.  Involved in the control of actin-cytoskeleton organization.
What are the official names of this protein?
TBC domain-containing protein kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Mainly localized in the cytoplasm during interphase. During metaphase, TBCK accumulates at the mitotic spindle. At the end of mitosis, it is detected at the midbody.
Protein: PCYA_TRIV2
Sequence: MSLTSIPSLREQQHPLIRQLADCIEEVWHQHLDLSPYHLPAELGYVEGRLEGEKLTIENRCYQTPQFRKMHLELAKVGNMLDILHCVMFPRPEYDLPMFGCDLVGGRGQISAAIADLSPVHLDRTLPASYNSALTNLDTLNFSQPRELPEWGNIFSDFCIFVRPSSPEEEAMFLGRVREFLQVHCQGAIAASPVSAEQKQHILAGQHNYCSKQQQNDKTRRVLEKAFGTDWAENYMTTVLFDLPE
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: Y1565_ARCFU
Sequence: MSLGLIFALLLTHAAAAKEIGIKTVNDYIKQGESHWYTSYVTSHTFDVYLVWNNPSNSLTLTVYSPDGS
What are the official names of this protein?
Uncharacterized protein AF_1565.
Protein: ATPE_MYCPU
Sequence: MQLQLIITTPNGIFFNEKVDIVTVVTAGGHIGIQYGHQPLISTIEISELHINTEGHKDYRICSINGGLLYVEKDKANIITGAIEFKEDIDIEKARREHDYLVEILSNSKNKDSDYFRNELKLKKVINRLKISSNSTQSPKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ITSN1_XENLA
Sequence: MAQFGTPFGGNLDIWAITVEERAKHDQQFHGLKPTAGYITGDQARNFFLQSGLPQPVLAQIWALADMNNDGRMDQLEFSIAMKLIKLKLQGYPLPSILPSNMLKQPVAMPAAAVAGFGMSGIVGIPPLAAVAPVPMPSIPVVGMSPPLVSSVPTVPPLSNGAPAVIQSHPAFAHSATLPKSSSFGRSVAGSQINTKLQKAQSFDVPAPPLVVEWAVPSSSRLKYRQLFNSQDKTMSGNLTGPQARTILMQSSLPQSQLATIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPILPPEYIPPSFRRVRSGSGLSIMSSVSVDQRLPEEPEEEEPQNADKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQDQERKRQQDLEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNREQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRHEIESTNKSRELRIAEITHLQQQLQESQQLLGKMIPEKQSLNDQLKQVQQNSLHRDSLLTLKRALETKEIGRQQLRDQLDEVEKETRAKLQEIDVFNNQLKELRELYNKQQFQKQQDFETEKIKQKELERKTSELDKLKEEDKRRMLEHDKLWQDRVKQEEERYKFQDEEKEKREESIQKCEVEKKPEIQEKPNKPFHQPPEPGKLGGQIPWMNTEKAPLTINQGDVKVVYYRALYPFDARSHDEITIEPGDIIMVDESQTGEPGWLGGELKGKTGWFPANYAERMPESEFPSTTKPAAETTAKPTVHVAPSPVAPAAFTNTSTNSNNWADFSSTWPTNNTDKVESDNWDTWAAQPSLTVPSAGQHRQRSAFTPATVTGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKNDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPLRKSTSIDSTSSESPASLKRVSSPAFKPAIQGEEYISMYTYESNEQGDLTFQQGDLIVVIKKDGDWWTGTVGEKTGVFPSNYVRPKDSEAAGSGGKTGSLGKKPEIAQVIASYAATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTNKSTPTEPPKPTSLPPTCQVIGMYDYIAQNDDELAFSKGQVINVLNKEDPDWWKGELNGHVGLFPSNYVKLTTDMDPSQQWCADLHLLDMLSPTERKRQGYIHELIVTEENYVSDLQLVTETFQKPLLESDLLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILTAQLPHMQPYIRFCSCQLNGAALIQQKTDEVPEFKEFVKRLAMDPRCKGMPLSSFLLKPMQRVTRYPLIIKNIIENTPENHPDHSHLKQALEKAEELCSQVNEGVREKENSDRLEWIQGHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQIIKPLGSSGNDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNIVEGIELKPCRTHGKSNPYCEITMGSQCHITKTIQDTLNPKWNSNCQFFIKDLEQDVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP
What is the function of this protein?
Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery.  Acts as guanine nucleotide exchange factor (GEF) for cdc42, and thereby stimulates actin nucleation mediated by wasl and the arp2/3 complex (By similarity).  Involved in endocytosis of activated egfr, and probably also other growth factor receptors (By similarity).
What are the official names of this protein?
Intersectin-1.
What are the subcellular locations of this protein?
Endomembrane system. Synapse, synaptosome. Cell projection, lamellipodium. Cell membrane. Membrane, clathrin-coated pit. Recycling endosome. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus envelope. Note=Shuttles between the cytoplasm and nucleus in an XPO1/CRM1-dependent manner.