PharMolix/UniProtQA huggingface dataset:
Protein: ASTB_PSEPF
Sequence: MKSYEVNFDGLVGPTHNYGGLSYGNVASQSNSQQSSNPKEAALQGLAKMKALMEMGFQQGVLAPQERPDVAALRRLGFSGTDAQVIERAAKEAMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFANQQHFAHHAALPAVAQFGDEGAANHTRFCREYGDAGVEFFVFGRSAFDTRYPAPQKYPARQTLEASQAVARLHGLRDDGVVYAQQNPAVIDQGVFHNDVIAVGNGEVLFYHEDAFLDTDQMLAELQAKLAKVGGKFQSVCVPRSAVTVDDAVRSYLFNSQLLSRPDGSMLLIVPEECRGNERVWNYLQGLTSSGGLIREVKVFDLKQSMQNGGGPACLRLRVALNETELAAVNPGVIMTAPLYGSLTAWVEKHYRDRLTESDLADPQLLLECRTALDELTQILKLGAVYPFQIN
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: C86A8_ARATH
Sequence: MEISTALMILSAITAYFLWLTFISRCLKGPRVWPILGSLPGLIENCERMHDWISDNLRACSGTYQTCICAIPFLAKKQGLVTVTCDPRNLEHILKNRFDNYPKGPTWQAVFHDLLGQGIFNSDGDTWLFQRKTAALEFTTRTLRQAMARWVNRAIKLRFLPILENARLGSEPIDLQDLLLRLTFDNICGLTFGKDPRTCAPGLPVNTFAVAFDRATEASLQRFILPEILWKFKRWLRLGLEVSLTRSLVQVDNYLSEIITTRKEEMMTQHNNGKHHDDLLSRFIKKKESYSDETLQRVALNFILAGRDTSSVALSWFFWLITQHPAIEDKILREICTVLVETRGDDVALWTDEPLSCEELDRLVFLKAALSETLRLYPSVPEDSKRAVKDDVLPDGTFVPAGSSITYSIYSAGRMKSTWGEDCLEFKPERWISQSDGGRFINHDPFKFVAFNAGPRICLGKDLAYLQMKSIASAVLLRHRLTVVTGHKVEQKMSLTLFMKYGLLVNVHERDLTAIAADLRECKSNVVNDGVGNGVSS
What is the function of this protein?
Catalyzes the omega-hydroxylation of various fatty acids (FA).  Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18.  May be involved in the biosynthesis of cutin in the epidermis which prevents post-genital organ fusions.  Hydroxylated FAs may be important for trichome differentiation, establishment of apical dominance and senescence.
What are the official names of this protein?
Cytochrome P450 86A8, Protein LACERATA.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYP_MYXXD
Sequence: MKGAPHMAEKLTPREKGFSEWYVDLVQKAKLADYSDVKGCMVIRPNGYALWENMQRVLDKMFKDLGHKNAYFPLLIPESYLKKEAEHVEGFNPQLAVVTHAGGSKLEEPYVIRPTSETIINRSFAKWIQSYRDLPLLLNQWANVMRWEMRTRLFLRTTEFLWQEGHTCHETEEDAEKETRQMLEVYRTFAEDYMAMPVMTGQKSESERFAGALRTYSIEAMMQDKKALQAGTSHNLGQNFAKAFDTQFQGRDGKMHHVWQTSWGVSTRLIGGLIMTHSDDAGLIVPPKLAATHVVIIPIFGKASDAEKAQVLEKTNALAADLRKAGLGVVLDDDDTKSPGFKYNEHELIGTCLRIELGPKDLAKNSCVMVRRDVRQKEFVSLDEAVSKAQAMLDAMQKDLFTKAKSFRDSHTFEVNSYEELKEKADQGFLLAHWNLDPKVEARIKEETGLTTRCRPFDLKQEPGKCVVTGEPSPGRIVFSKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZF_STAS1
Sequence: MMRRGDVYLADLSPVQGSEQGGIRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKSKYKLDKDSVILLEQIRTLDKNRLKEKLTYLSDKKMKEVNNAIDISLGLHTIRSHKA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis.  It cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA.  Neutralized by coexpression with cognate antitoxin MazE.
What are the official names of this protein?
Endoribonuclease MazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: MUTS2_FUSNN
Sequence: MNKHSFNVLEFDKLKELILANIVIDHNREVIENLEPYKDLSALNNELKTVKDFMDLLSFDGGFEAIGLRNINSLMEKIKLIGTYLEVEELWNINVNLRTVRIFKSRLDELGKYKQLREMIGNIPNLRVIEDVINKTINPEKEIKDDASLDLRDIRLHKKTLNMNIKRKFEELFEEPSLSNAFQEKIITERDGRMVTPVKYDFKGLIKGIEHDRSSSGQTVFIEPLSIVSLNNKMRELETKEKEEIRKILLRIAELLRNNKDDILIIGEKVMYLDILNAKSIYAVENRCEIPTVSNKEILSLEKARHPFIDKDKVTPLTFEIGKDYDILLITGPNTGGKTVALKTAGLLTLMALSGIPIPASENSKIGFFEGVFADIGDEQSIEQSLSSFSAHLKNVKEILEAVTKNSLVLLDELGSGTDPIEGAAFAMAVIDYLNEKKCKSFITTHYSQVKAYGYNEEGIETASMEFNTDTLSPTYRLLVGIPGESNALTIAQRMGLPESIISKAREYISEDNKKVEKMIENIKTKSQELDEMRERFARLQEEARLDRERAKQETLIIEKQKNEIIKSAYEEAEKMMNEMRAKASALVEKIQHEEKNKEDAKQIQKNLNMLSTALREEKNKTVEVVKKIKTKVNFKVGDRVFVKSINQFANILKINTSKESAMVQSGILKLEVPFDEIKIVEEKKEKVYNVNNHKKTPVRSEIDLRGKMVDEAVYELETYLDRATLNGYTEVYVIHGKGTGALREGILKYLKACKYVKEYRIGGHGEGGLGCTVVTLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: EF1B_METM6
Sequence: MATVIAKVKVMPTSPEVEKEALKETLKELVEKNDAKCRGVSDEPLAFGLYTVFVMVEMEEKEGGMDPIEEAMNALENVESAEVVELSLV
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: BIOD_MYCS2
Sequence: MTVLAVTGTDTGVGKTVTTAALACAARLARRDVAVCKPVQTGTIDGDDDLGEVRRLSGVTALHGGWRYPEPLAPVAAAGRAGAPLPTRTELVGSVRAVDAAGRLTIVEGAGGLLVALGADGVTLRDLAHDLGAQVLIVVSPGLGTLNHTALTLEALAAHGLSCAGLVIGAWPAEPGVAELDNRTALEALAPVRAVLPAGAGAASPERFEALSAAAFDADWITSLS
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJGA_SALHS
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAELVDLGKNALDKIPLDADLRDAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLEHLRDRLIVEGDDAVAEVLTLWPHADRQQLRSLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: M32_STRTR
Sequence: NHQLTQENERLTQK
What is the function of this protein?
This protein is one of the different antigenic serotypes of protein M.  Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis.
What are the official names of this protein?
M protein, serotype 32.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: ZC3HF_DANRE
Sequence: MPPKKPAPAAANKKTQEKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTQQVKFGQQNARQIAAAESEKTKKKDDKKKELSELNELFKPVVAAQKVSKGVDPKSVLCAFFKQGQCTKGDKCKFSHDLSLERKCEKRSLYVDGRDDELLEKDTMENWDEKKLEEVVNKKHGEAEKKKAKTQIVCKYFLDAIENNKYGWFWVCPGGGDNCMYRHALPVGFVLKKDKKNEEKNEEEISLEDLIETERSLLGANVTRITLETFLAWKKRKRQEKLAKAEQDMERKKADFKAGRALGVSGREVFEFRPELVDDDDEEADDTKYAEEDYNYGMSNQVEDTEEVQDIDIARFIPKEVDNAGITVASADRFTAKAPPTNDIDDNKLSEASGGTMENGEHSEDQTLEDGETNEESEAVPVDENLFTGEDLDELEEELNTLDLDE
What is the function of this protein?
Protects drg1 from proteolytic degradation.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 15.
What is the protein family that this protein belongs to?
Belongs to the ZC3H15/TMA46 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARLY_ESCF3
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQVQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAENNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEELPLSELQKFSQVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAEP_SALHS
Sequence: MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALSESVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: RNY_LACJO
Sequence: MVNTILVPVAVAIVSVLVGGCAGYSIRKNKWETQAQNAAHDAKHILADAESKAKAVEADLASQKEAMKKAAADAKKEKILEAQEEIHHYRERVDNELNERRQEVSRQENRLLQREDAIDHKDSLLDQKDSQLTQKENQIKKLQAQVLEKENRADQLVTEREKKLYEVAELNQEDAKKIVLDKLSDQLVKERAEMIEESNQLAKAKADHFARKVIVDAIQSSAADTVSEKTVSVVNLPSDDMKGRIIGREGRNIRSFEALTGVDVIIDDTPDVVVLSGFDPIRREIAKRALERLIKDGRIHPARIEEMVDRARKEVNDDIYEAGESALMELGIHKMHPELVKILGRLKYRTSYGQNVLSHSIEVGKLTGVMAAELGLDEKIAVRAGLLHDIGKSIDHEIEGSHVEIGVELARKYHEPDLVVNAIAAHHDDVPKLSFIAELVVAADTISSARPGARSESLENYIRRLEQLETIAKGHIGVKQAYAIQAGREIRVMVEPDKISDARTTILAHDIRNQIEQDMEYPGNIKVTVIREKRAVAIAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TPC12_MOUSE
Sequence: METAKDGEQSPSEASPSAQAGPENIPEPMSREEESQPLYHEETIDLGGDEFASEENEPTSEGSHNFGDKLNEHMMESVLISDSPNNSEGDVGDLGCLQDVGEPPRGATDHRLPSSTDKEVVDTLSNGSETDGDDTPRDISDMTPDSRASLKEDSTQEDVTSMPALENAATEEVGPKDSLAPREEQTSEVSSNQSSSKDEPLPVCTIFSQATATPSQPHLFLQDGFESQMVKSPSFSSTSETSAKTPPPMVQPSPSLSTFFGDTMSSNSLASDFFDSFTTSTFISVSNPNAGSPVPEKLSSLTAPVGEKSPDSTSPSYSTRMDRSESGVSRAPLDVPESPKPFSQIQAVFAGSDDPFATALSMSEMDRRNDAWLPSQATREVLMSVATQQYGTVFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAKRQVLNASSVEQSFVGLKQLISCRNWRAAVDLCGRLLTAHGQGYGKNGLPTSHTTDSLQLWFVRLALLVKLGLFQNAEMEFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHRVKTVCSKILANLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYVLAVDAYLTVIKYYPEQEPQLLSGIGRILLQIGDIKTAEKYFQDVEKVTQKLDGLQGKIMVLMNRAFLYLGQNNFAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLEAMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQSLLEAVASKEGDSFNTQCLKLA
What is the function of this protein?
Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.  Also plays a role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores.
What are the official names of this protein?
Trafficking protein particle complex subunit 12, Tetratricopeptide repeat protein 15, TPR repeat protein 15.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment. Nucleus. Note=Mainly localizes to structures resembling the Golgi and a small amount is found in the nucleus.
Protein: SPC25_DROAN
Sequence: MAVGLDRADKSNYALRLKEMFNKEIRLQCRETNISKMSSKFHDNLLTAMEKADWQQRELERIERQLVLNRQELEKRLLLEKELTRELEATKLQEATVREHNNELMECIHALKRATGTSINHDALPARVKGVTVLRNTDGDQWIPFDLAVTDTEGLNSLCQKLQSNNIDVNKWRQLVSLATEMSMKWNYSTPNRRDNAKVDIIEIDLTSPTNQIIL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: 3SAN_NAJNG
Sequence: LKCNRLIPPFWKTCPEGKNLCYKMTMRLAPKVPVKRGCIDVCPKSSLLIKYMCCTNDKCN
What is the function of this protein?
Basic protein that binds to cell membrane and depolarizes cardiomyocytes.  This cytotoxin also possesses lytic activity on many other cells, including red blood cells.  Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes.  It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation.  Inhibits protein kinases C.  It binds to the integrin alpha-V/beta-3 with a moderate affinity.
What are the official names of this protein?
Naniproin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: MIAB_MYCBO
Sequence: MVAHDAAAGVTGEGAGPPVRRAPARTYQVRTYGCQMNVHDSERLAGLLEAAGYRRATDGSEADVVVFNTCAVRENADNRLYGNLSHLAPRKRANPDMQIAVGGCLAQKDRDAVLRRAPWVDVVFGTHNIGSLPTLLERARHNKVAQVEIAEALQQFPSSLPSSRESAYAAWVSISVGCNNSCTFCIVPSLRGREVDRSPADILAEVRSLVNDGVLEVTLLGQNVNAYGVSFADPALPRNRGAFAELLRACGDIDGLERVRFTSPHPAEFTDDVIEAMAQTRNVCPALHMPLQSGSDRILRAMRRSYRAERYLGIIERVRAAIPHAAITTDLIVGFPGETEEDFAATLDVVRRARFAAAFTFQYSKRPGTPAAQLDGQLPKAVVQERYERLIALQEQISLEANRALVGQAVEVLVATGEGRKDTVTARMSGRARDGRLVHFTAGQPRVRPGDVITTKVTEAAPHHLIADAGVLTHRRTRAGDAHTAGQPGRAVGLGMPGVGLPVSAAKPGGCR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYTM_SOLTU
Sequence: MAIVGGLVDVPFENKVEFDDLARFAVQDYNQKNDSSLEFKKVLNVKQQIVAGIMYYITFEATEGGNKKEYEAKILLRKWEDLKKVVGFKLVGDDSTMPGGIVNVPNPNNTKFQELARFAIQDYNKKQNAHLEFVENLNVKEQVVAGIMYYITLAATDDAGKKKIYKAKIWVKEWEDFKKVVEFKLVGDDIAKLGGITDVPFPNNPEFQDLARFAIQVYNKKENVHLEFVENLNVKQQVVAGMMYYITLAAIDAGKKKIYETKIWVKEWEDFKKVVEFKLVGDDSAKTGGIINVPNPNSPEFQDLARFAVQDYNNTQNAHLEFVENLNVKEQLVSGMMYYITLAATDAGNKKEYEAKIWVKEWEDFKKVIDFKLVGNDSAKKLGGFTEVPFPNSPEFQDLTRFAVHQYNKDQNAHLEFVENLNVKKQVVAGMLYYITFAATDGGKKKIYETKIWVKVWENFKKVVEFKLVGDDSAKLGGIINVPFPNNPEFQDLARFAVQDYNKKENAHLEFVENLNVKEQLVAGMLYYITLVAIDAGKKKIYEAKIWVKEWENFKKVIEFKLIGDDSAIIGGFTDVPFPNNPEFQDLARFAVQDYNKKENAHLEYVENLNVKEQLVAGMIYYITLVATDAGKKKIYEAKIWVKEWEDFKKVVEFKLVGDDSAKPGGIIIVPFPNSPEFQDLARFAVQDFNKKENGHLEFVENLNVKEQVVAGMMYYITLAATDARKKEIYETKILVKEWENFKEVQEFKLVGDATK
What is the function of this protein?
Probably has a role in the plant's defense system.
What are the official names of this protein?
Multicystatin, MC.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
Protein: RS6_BACC1
Sequence: MRKYEIMYIIRPGVEEEAQKALVERFAGVLTNNGAEIINTKEWGKRRLAYEINDLREGFYMILNVKSNAEAINEFDRLAKINEDILRHIVVKEEEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: VP1_CPBDV
Sequence: MNVKGASDKAQLAMQAEWEEVLAPEGALAVEEASSVLKISDDERRSYAAYIDNIIQENEIDVVYGHSRGAAIASELESDVQIIGLDGAMVIANDQANFLNIRQDDSEGYGFDRTIAGPYENTVIVKGGAFHKVAVPEGYHTKKPKASQEALERAKARKHNRARHIARAIDRLTARKTDKELEEIYWRERRKKNKNEFSKALIEFIEEQLL
What are the official names of this protein?
Viral protein 1, VP1.
Protein: FABZ_TERTT
Sequence: MLDILEIRKYLPHRYPFLMIDRVVELIEGESITAYKNVSINEEIFQGHFPHFPVFPGVLLIEAMAQACGVLGFKTANKTPEDGSIYLFAGIDGVRFKRQVVPGDRVYFECKVVSAKRGIWKFDCVAKVDGELVTSATIMCADRVVG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_MALP2
Sequence: MKENNKTIEAKNKELRDATKEFNEKLQKFLKDKVKKGFQIKNPNYKIDDNKISSNEVFKNNKNDFELNLPKNTWEEKTNKPESFENYKNVIPPYEDKFLPENFKEKFAPKNIKSEPLINKKDNLKEKNNNPVFDEVKIQEDDKFFDFSKFSETVSNQPENILKIEENDFKEIHDDFVSQYETFSKLETKENTNDLKTNLSSDTIKTIESKNEPEVQIESEIKDDSLEKEISEDDSFMDIFKAEQPDNQEDDSFVIDEEKAKEEYQEIKTNKSIVSDSHKIDIYEENEDLMKLNTLKSDKGIIYQIFGPVVDVKFARNQMPNINDCLEVKLPNNKKLVLEVALLEGDDVARCISMGSTEGLYRGLEVINTKNPIMAPVGSAVLGRMFNVVGEPIDNKPMPEKVEYSPIHKKPPSFDEQSTKTEIFETGIKVIDLLVPYVKGGKIGLFGGAGVGKTVLVQELIHNIATGHGGLSIFAGVGERTREGNDLYHEMIDGGVINQTALVFGQMNEPPGARMRVALTALTMAEHFRENNKQDVLLFIDNIFRFSQAGSEVSALLGRIPSAVGYQPTLAFEMGQLQERITSTKSGSITSVQAVYVPADDLTDPAPSTTFAHLDAKTVLDRKIASLGIYPAINPLESSSRMLDPSIVGIEHYKVARSVQTILQKFEELQDIIAILGIDELSEEDKLTVSRARKIRNFLSQPFFVAEKFSHKSGKYVSTQDTISGFSEIIEGKCDDIPEQYFLYVGGIDDVHKNYVAANSNNKVNSSNKPLNSENKSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LPXK_ECOLU
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTGAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVVDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGMRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SHU2_YEAS2
Sequence: MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKVCCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RB45B_ARATH
Sequence: MMQQPPPGGILPHHAPPPSAQQQYGYQQPYGIAGAAPPPPQMWNPQAAAPPSVQPTTADEIRTLWIGDLQYWMDENFLYGCFAHTGEMVSAKVIRNKQTGQVEGYGFIEFASHAAAERVLQTFNNAPIPSFPDQLFRLNWASLSSGDKRDDSPDYTIFVGDLAADVTDYILLETFRASYPSVKGAKVVIDRVTGRTKGYGFVRFSDESEQIRAMTEMNGVPCSTRPMRIGPAASKKGVTGQRDSYQSSAAGVTTDNDPNNTTVFVGGLDASVTDDHLKNVFSQYGEIVHVKIPAGKRCGFVQFSEKSCAEEALRMLNGVQLGGTTVRLSWGRSPSNKQSGDPSQFYYGGYGQGQEQYGYTMPQDPNAYYGGYSGGGYSGGYQQTPQAGQQPPQQPPQQQQVGFSY
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
What are the official names of this protein?
Polyadenylate-binding protein RBP45B, Poly(A)-binding protein RBP45B, RNA-binding protein 45B, AtRBP45B.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding RBP45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NNRE_PLAKH
Sequence: MKKELMLRCANNFVLQNSVCLLGFLRLVKSHLTGRVGIIKARSFKGKRTNCTSTCVHLNNMEVTYLSQSLAQTIDNELMSDDVGYTTEQLMELAGLSIAQIICREYSFDKFKKILIFCGPGNNGGDGLVAARHLKQFGYDITVAYPKENTKVLFQRLLNLLHHYHVPVVKSATGEDIKMYDLVVDALFGFSFRGEPRSPFDEIIHMINQSNKPVVSVDVPSGINIDGDTAGTALSVNSEMNISLMLPKEGVRHYRKKHYLGGRFIPNSIVEKYNLKIPQFTGDNSYVQL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: ILVC_ARTS2
Sequence: MTEMFYDDDADLSIIQGRKVAIVGYGSQGHAHALNLRDSGVEVTIALKEGSSSIAKAQDAGFTVKNVADAAEWADVIMILAPDQHQRSIYNDSIKDKLTPGKALAFAHGFNIRFGYIKAPEGVDVILIAPKAPGHTVRREFEAGRGIPDIIAVEQDATGAAWDLAKSYAKAIGGTRAGVIKTTFTEETETDLFGEQAVLCGGVSQLVQYGFETLTEAGYQPQIAYFEVLHELKLIVDLMWEGGIAKQRWSVSDTAEYGDYVSGPRVITPEVKENMKAVLADIQNGAFAKRFIEDQDNGGVEFKALRAKAEQHPIESVGRELRGLFSWQQQDEDYVEGSAAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ATG16_KLUMD
Sequence: MEYELLESIRARDLVDKRFSQLFEEVPLVPKLEKAGEGDTNVKESSIKNLKDYLKLRDEEVYKLKDILKLKNRDTERLNDELLSANIESNLLQERLEKLQQEYDRLIERWLLKAQKEADTMNSHFK
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate (By similarity).  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS) (PubMed:26442587).  Recruits also ATG3 to the PAS (By similarity).  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).
What are the official names of this protein?
Autophagy-related protein 16.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.