PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_WHV5
Sequence: MDIDPYKEFGSSYQLLNFLPLDFFPDLNALVDTATALYEEELTGREHCSPHHTAIRQALVCWDELTKLIAWMSSNITSEQVRTIIVNHVNDTWGLKVRQSLWFHLSCLTFGQHTVQEFLVSFGVWIRTPAPYRPPNAPILSTLPEHTVIRRRGGARASRSPRRRTPSPRRRRSQSPRRRRSQSPSANC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TA2R7_PONPY
Sequence: MTDKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWIKKRKIASIDLILTSLAISRICLLCVILLDCFILVLYPDVYATGKEMRIIDFFWILTNHLSIWFATCLSIYYFFKIANFFHPLFLWMKWRIDRVISWILLGCMVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHASIKLLLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISFLLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVIWKVMSILKGRKFQQHKQI
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 7, T2R7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRVB_RANTE
Sequence: KVFEILDMDRSFIEEELKLFALSSAETAAFLKIGVEEFQALVK
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin beta.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Cytoplasmic in muscle. Secreted in cutaneous mucus.
Protein: RUVA_ALIF1
Sequence: MIGRLRGNLLEKQPPELLIEVSGIGYEVQMPMSCFYELPEVGSEAIIYTHYVVREDAQLLYGFNTKNERALFREVIKANGVGPKLGLAILSGMTAAQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPMDDGSEFITSPQSAVDEAVSALIALGYKPQQASKTVSQIAKPDMTSEVLIRESLKSMI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: I1BG_CONRA
Sequence: GHVPCGKDGRKCGYHTHCCNCCLSGICKPSTSLIGCSTSSFT
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.16.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_I81A1
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRIDGKWTRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSGFIRGKKVVPRGKLSTRGVQIASNENVEAMDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATVMAAFIGNNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MVHB_METTM
Sequence: MIVVNKEDCIRCGACQGTCPTAAIEVTPEDVIYCDICGGEPKCVDACPTGALKIEDLVVDEAGNTQGRIVFNPDKCNECGDCVEVCPPQILKLDEGKVKKIPLQGFCVMCQKCVDICPVGVIGVEGIKEPAKVELEIEGPIFIADCVGCGMCVPECPVDAITLEKVGGVIEIDEDTCIKCGVCAQTCPWNAVYISGKKPEKRAKEIRKFELDEEACIGCNTCVEACPGDFIVPKSSNLTVELPAICTACGLCEQLCPVDAIDLDVELGPAKPASEEGLVWDEGKCDFIGACANICPNDAIRVVTREGMKLPDNEKVDEEPSFAMCTRCGACTMACPKGALSLVDMDKVIDGEVVKRKRVQYNPALCDQCGDCIEACPYDMLKLTDEKVPLKGFCILCDQCIPACPKGALSLK
What are the official names of this protein?
Polyferredoxin protein MvhB.
Protein: THIQ_RHIME
Sequence: MSSTALAVKGVEISFETTTLAFDCAVPAKRIVAVAGASGSGKSTLFNIIAGFEQPGRGEVRILGEEMTGRAPAERPVSIIFQEHNLFAHLDVATNVGFGISPALRLDAANRTKVEDALARVGLAGFGKRLPPTLSGGERQRVALARAFVRHRPILLLDEPFAALDPGMRAEMRALISDLHEEEGNTILMITHHPDDVRALADSVLFLDRGRIVAHDEVDRFLGRRDIAAINRFLGNEG
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRE_ORYSJ
Sequence: MAPTAAVAGGGVEAEALLGLLQRVQSEALRAFGPNDFDPKLYVDLPLAADASAAAALASLPRAAPSRGEMEAYISRYFALAGSDLVAAADPPDFERDPPGFLPRVERAEARAWALEVHALWKDLTRRVAPAVAARPDRHTLLPLPGRVVVPGSRFREVYYWDSYWVVRGLLVSKMYETAKDIVLNLVYLVEKYGFVLNGARSYYTNRSQPPLLSSMVLDIYMATGDMAFVRRVFPSLLKEHSFWMSEVHNVAVMDNHGRVHNLSRYQAMWNKPRPESATIDEEFASKLSTAAKEKFYHQVASTAETGWDFSSRWMRDSTDMTTLTTSCIIPVDLNTFILKMEQDIAFFAKLIGESTTSEIFSEASKARHNAIDSVLWNADMEQWLDYWLPTDGNCQGVYQWKSISQNRAIFASNFVPLWLNAQHSGLEQFVDEAKSVRVMRSLQKSGLLQPAGIATSLSNTGQQWDFPNGWAPLQHLIVEGLLRSGSGEARELAEDIATRWVRTNYDAYKATGAMHEKYDVVTCGKSGGGGEYKPQTGFGWSNGVILSFLDEFGWPQDKKIDC
What is the function of this protein?
Involved in the regulation of trehalose content by hydrolyzing trehalose to glucose.
What are the official names of this protein?
Probable trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
Protein: MAP21_PYRTR
Sequence: MGSKSPEDHRQGPDGGSADAAVTIINPPKSAAASGLLQGMLEGQDEDGDDDDDEKTGINVKTYDGAKKKRKRNKKKSKKVAVIQQTFPPRIPLATLFDNQPYPEGQIVDHVVKDDNIKRTTTEELRHVAALNDMDDDFLKDYRKAAEVHRQVRHHAQTIAKPGVSMTRLAEEIDEGVRALTGHTGLETGDALKAGLAFPTGLCLNHVGAHWTPNAGAKEVILKHDDVLKVDFGVHVNGRIVDSAFTVAANPVYDNLLAAVKAATNTGLGEAGIDARIDHISEAIQEVMESYEVELNGKTIPVKAVRNITGHNILRYRIHGDKQVPFVKTKTDQRMEEGDIFAIETFGSTGKAHLRDDVGVYGYGRNENMSPAVLHQSSAKSLLKTIDANFGTLVFARRQLERLPGVEKYHLGMRTLVNSGLVESYAPLVDITGSYIAQFEHTVLLRPNCKEIISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-1, MAP 2-1, MetAP 2-1, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2776_BACC1
Sequence: MNQVRKWNIIGGRVIKTGIAVFLTVLVCEFFNIPTIFAVITAIVTIEPTATDSIKKGLVRFPASTIGSAYAMTFTFFLGHQALSYALAAMFTIVTCQKLKLHAGTLVATLTAVAMIPITADHYFTAFLIRLATTSTGIIVSTLVNFFILPPHYVKTISGCTEELFVKTAHIMEEWLNALIEGKVITKETTHNLSKVNLLLHKAVQFVQYEQKDWKYHRHTKKEMRSFLLVQKQLHLLQQIIYHIDNLARTPIETCDWSQNEKEILRRTIHSIISILRNNCNKIDEEHFKLIDELDKQFWNYKNDLAHCKPNQYHHHFSSESIILFEVLSIHDMLEELKQIXEKYEGENQFNCSVH
What are the official names of this protein?
UPF0421 protein BCE_2776.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYL_CORA7
Sequence: MTNPSDNTTHRYTPELAAQIESAWQQYWKDNGTFNAPNPVGPLAEEGKELPAEKMNIQDMFPYPSGAGLHVGHPLGYIATDTYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTEANINNMRRQLGMLGLGHDPRRSVASTDPEFYKWTQWIFLQIYNSWFDEEQQKARPISELIKELEVGKRTTKDGRYYADLTKEEQRQALDEFRLVYLSNSTVNWCPGLGTVLANEEVTAEGKSERGNFPVFRKNLRQWMMRITAYSDRLLDDLELLDWPEKVKSMQRNWIGRSRGAEVSFHAEGYNIDVFTTRPDTLFGAEYVVLAPEHELVDALLSPIPYEDDVDKRWTFGHDDPKEAVEAYRASIAAKSDLERQENKEKTGVFLGTYATNPVNGKQIPIFIADYVLTGYGTGAIMAVPAHDTRDYEFATVFGLPITEVVAGGDITKEAYTESGQAVNSANDSLDINGMSKDEAIATIIPWLEEQGVGREKIQYKLRDWLFARQRYWGEPFPIVYDEAGQAYPLPESMLPIELPEVEDYKPVSFDPDDADSSPQPPLAKAREWVEVELDLGLGDGPKTYYRDTNVMPQWAGSSWYQLRYIDPTNDEIFCDLENERYWTGPRTEEHGANDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGYVSSKEPYRRLYNQGYIQAYAYTDSRGVYVPAAEVEEKDGKFYYNGEEVNQEYGKMGKSLKNSVAPDDICRDYGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRLWRLAIDENSGELSTTDAELSEDDLKHLNRTIAGVRDDYENLRLNTVVAKLIEYVNYLTKAYPKGAPRAAVEPLAQLVSPVAPHIAEELWKRFGHEGTITYEAFPEFDEKYLVDDEIEVPVQINGKVKARVMVPADADQATVVGIAKDDERIAELTAGKNVVKEIYVPGRMVNLVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMOD_METCA
Sequence: MVESAFQPFSGDADEWFEEPRPQAGFFPSADWHLLKRDETYAAYAKDLDFMWRWVIVREERIVQEGCSISLESSIRAVTHVLNYFGMTEQRAPAEDRTGGVQH
What are the official names of this protein?
Methane monooxygenase component D.
Protein: LIPB_SALPA
Sequence: MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y708_CHLMU
Sequence: MRRSVCYVTPSVARAGQISTWRFEYSSANFLPEGTLLKFDLGIDGRPIDWEIPSTDLSQPCNTIYLETPSESIVTAKAVYAPGSYIPTFEFILPCEIEAGDTFSIILGSSPNFPQEDASGNGAQLFTQRRKPFSLYVDPTGKGNFEDPDIFTIDIRGNVLKNIRIFAPSYVVKNKRFDITVRFEDEFGNLTNFSPEETQIELSYEHLRENLSWQLFIPETGFVILPNLYFNEPGIYRIQLRNQATKEIFTSAPIKCFTETSPHLLWGLLHGESERVDSEGNIESCLRYFRDDCALNFFATSSFEIQDGLTPETIKSINQTVSDFNEEDRFIALSGAQYVSEEPGEGIREVLLIKEPKSPGKHKECKLFPLSKLYKQSTSHELISIPSFTASKKFGCDFQNFHAEFERVVEIYNAWGCSERTEAEGNPFPIKGSIDSENPEGTILSALKRNLRFGFVAGGLDDRNLYSNFFDSDQQQYSPGLTAVICNKYSRDSLLEALYQRQCYATTGQRIIVSFQITSAPMGSELSTAIKPGLMINRHISGYVAGTAKISTIEIIRNGDTLHTFYPDGNNFEYEYDDLTPFAQATLADPKNGAPFAFYYLRVTQENGAMAWSSPIWIDLN
What are the official names of this protein?
Uncharacterized protein TC_0708.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0512/CT_425/TC_0708 family.
Protein: MOBA_CUPPJ
Sequence: MIARDDITGLILAGGRGSRMGGTDKGLQPLRGTPMAMHTMMRLTPQTGALMINANRNLAAYESFGVPVVTDSVPDFAGPLAGMLAGLEQCQTGWMVTAPCDSPFLPADLVPRLAQAIEAEGAELAIPVTVDTDGRRQLQPVFCLMPVSMLDDLIAYLNGGGRKIETWATSHRLAEVLFDDAGAFANINTLDELRTHEAG
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATC_ARTSF
Sequence: MEDAHAKKWEEVVDYFGVDPERGLALEQVKKNQEKYGPNELPAEEGKSLLTLILEQFDDLLVKILLLAAIISLVLALFEEHDDEAEQLTAYVEPFVILLILIANAVVGVWQEKNAESAIEALKEYEPEMGKVIRADKTGIQKIKARDLVPGDIVEISVGDKIPADLRLISILSTTLRIDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNVSAGKARGVVMGTGLNTAIGSIRTQMFETEEMKTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFNDPAHGGSWIKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFVFKDIPDDAAPELYQFELTGSTYEPIGETFMQGQKINAADYDAVKEITTICMMCNDSAIDFNEYKQAFEKVGEATETALIVLGEKLNPYNLSKAGKDRRSAALVVREDMDTRWKKEFTLEFSRDRKSMSSYCVPLKAGLLSNGPKMFVKGAPEGVLDRCTHVRVGTKKVPMTPAIMDKILEVTRAYGTGRDTLRCLALATIDDPMDPKDMDIIDSTKFVKYEQNCTFVGVVGMLDPPRKEVLDAIERCRAAGIRVIVITGDNKATAEAICRRIGVFGEDENTEGMAYTGREFDDLSVEGQRDAVARSRLFARVEPFHKSKIVEYLQGMGEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRRADEGLITGWLFFRYMAIGTYVGAATVGAAAHWFMMSPTGPGLNFYQLSHHLQCTPENEYFEGIDCEIFSDPHPMTMALSVLVTIEMLNAINSLSENQSLLVMPPWSNIWLISAICLSMTLHFVILYVEILSTVFQICPLTLTEWIVVLKISFPVLLLDEVLKFVARKYTDEFSFIK
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
What are the official names of this protein?
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type, Calcium pump.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GP55_BPPH2
Sequence: MMETQEKVLVLVGALFINTFNLNYKSIVLTHDSEQAYGFKDKWEAQKVAANVGGQVVIRTTSFKIV
What are the official names of this protein?
Gene product 5.5, gp5.5, Gene product 5B, gp5B, Protein p5.5.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus GP5.5 family.
Protein: BPT_VIBCH
Sequence: MSSDIQQIRIGLTNNHPCSYLADRMERVAVAIDPQMQTPETYEVLMANGFRRSGDTIYKPHCDHCQSCQALRIPAPDFVPSKSQKRLLKLLSQEFHWQLKPELDEDWYTLYARYIFARHRHGSMYPPNKMEFAKFARAKWLNTQYLHLYQGEKLVAIAVTDLLPNSASAFYTFYDPDISISLGTLAVLCQLNYCQQTKKQWLYLGYQIDECPAMNYKVRFNPHQRLVNQRWRG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACRZ_ECO57
Sequence: MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH
What is the function of this protein?
AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity.  This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
What are the official names of this protein?
Multidrug efflux pump accessory protein AcrZ, AcrAB-TolC multidrug efflux pump accessory protein AcrZ, Acridine resistance protein Z.
What is the protein family that this protein belongs to?
Belongs to the AcrZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CRYAB_TURME
Sequence: LIRRPFFSWLAPSRIFDQIFGEHLPESELLPVSPSFSPFLMRSPILRMPSWL
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: YCF4_AEGTA
Sequence: MNWRSEHIWVELLKGSRKRGNFFWACILFLGSLGFLSVGISSYLGKNIISILPSQEILFFPQGVVMSFYGIAGLFISSYLCCTILWNVGSDYDRFDRKEGIVCIFRWEFPGIKRRVFLRFLMRDIQSIRIQVKEGLYPRRILYMEIRGQGIIPLTRTDDQFFTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NOGG_RAT
Sequence: GGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWARYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
What is the function of this protein?
Essential for cartilage morphogenesis and joint formation.  Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite (By similarity).  Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6 (By similarity).
What are the official names of this protein?
Noggin.
What is the protein family that this protein belongs to?
Belongs to the noggin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_SINFN
Sequence: MRIGLFAVGRLKAGPEKDLAARYLDRFAKAGPAVGLELARLVEINESRAANAQTRKREEAAQLEKTLADGSLLLLLDERGKALDSESFATLLGTFRDGGKRDLMIAIGGADGLDPALHARADAVLCLGKMTWPHQLVRILIAEQLYRAVTILAGHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCHR2_MACFA
Sequence: MNPFHSSCWNTSAELSNKSWNKEFAYQTASAVDTVILPSMIGIICSTGLVGNILIVFTIIRSRKKTVPDIYICNLAVADLVHIIGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFRLTSWRTRYKTIRINLGLWAASFILALPVWIYSKVIKFKDGVESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPSVPKQRVMKLTKMVLVLVAVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSSINPFLYILLSGNFQKRLPQIQRRVTDKEIKNMGNTLKSHF
What is the function of this protein?
Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
What are the official names of this protein?
Melanin-concentrating hormone receptor 2, MCH receptor 2, MCH-R2, MCHR-2, G-protein coupled receptor 145, GPRv17, MCH-2R, MCH2, MCH2R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX53A_ETHRU
Sequence: MRSWFVFVALLAVVFLPSSLDALKCIQCDSQPNRDECKTTLPEARDCPQTVNNYCFKTETFNKNGDLSMLRRYCNVLASTQNGCVDLPGGLGKKCEYSCNTDGCNSVTGLVASRAAYLVTLLPIIFYALSRQ
What are the official names of this protein?
U-scoloptoxin(05)-Er3a, U-SLPTX(05)-Er3a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-05 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTP5_STYPL
Sequence: QESTVIVMLTRVNENGRRKCEKYWPDHREQTTFDNLIVSSINVSEYGQIIKRSFQLWNPNQPGKKLLVEQFHYITWPDHGVPITTSDLFNLRRMVIESQGNNPSPIIV
What are the official names of this protein?
Tyrosine-protein phosphatase 5.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: TRPC_CLOK5
Sequence: MILDDIVGVKKKELEIRKESKPLKDIVDELSRIDEFKIRNFKGALINDDISIIGEIKRASPSKGIIDRKFEFEDICSTYETLDIDAVSVLTEQHYFKGKDEYLKKAKEFISKPVLRKDFIVDEYQVYESKLLGADAVLLIVRILKENLDKFYKIASSIGLQCIVEVHNKSELDIALKIEPEIIGINNRNLENFTVDLKNTENLINYMPENTAVISESGIKTSMDFKYIKSLPINGVLIGEGLMKKIYDIESIKKFIDSVKSG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LC2B1_MORNI
Sequence: TQSTGTSQTIAVGLWGGPDN
What is the function of this protein?
Alpha-methyl-D-mannoside and D-mannose specific lectin.  Binds IgA.
What are the official names of this protein?
Agglutinin beta-2 chain isoform 1, Agglutinin II beta chain, isoform 1, MNA II beta, isoform 1.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: Y755_KLEP3
Sequence: MSIQNEMPGYNDVDQLLNQQGVGLTPAEMHGLISGLLCGGNTDSSWLPMVHDLTNEGLAFGHELAQALRNMHSAISDSLDDDGFLFQLYLPEGDAVSVFDRADALAGWVNHFLLGLGVSQPKLDKVKDETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFSRQQPTAPEVRKPTLH
What are the official names of this protein?
UPF0149 protein KPK_0755.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.