PharMolix/UniProtQA huggingface dataset:
Protein: COAA_XANP2
Sequence: MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSRLLSLYVAATQKLFRAMSYFLDSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLARWPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLPLLLRFLTDIKAGRRPVRAPLYSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDEDVIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTRQRADLILRKTGEHEVAEVSLRRL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQC_PSEPK
Sequence: MSDALPMSPAEFEQALRAKGAYYHIHHPYHVAMYQGRATREQIQGWVANRFYYQVNIPMKDAAILANCPDREVRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVGLDPDQLRSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPQHYPWIDPAGYEYFRTRLGQARRDVEHGLAITLQHYTTRAGQERMLEILQFKLDILWSMLDAMSMAYELNRPPYHSVTQERVWHKGITL
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: FDHE_SALTY
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUBC_ECO57
Sequence: MTETGGQPPVSFPVKDVAGLLFLLRRLTRRGRNAACGQCPASGRARDGRFYRSRLASVTVYASPSPFSDERPSSRFRGIFSPSKRRRLRYSTVGLTRYRTR
What are the official names of this protein?
Uncharacterized protein YubC.
Protein: MURA2_LEGPL
Sequence: MDKLLINGGKALHGEVVISGAKNAALPIMAASLLASDHVTISNVPHLKDITTMMELLGQLGAHLIVDEKMNVQVDSSQVNEFVAPYDLVKTMRASILVLGPMLARFGKADVSLPGGCAIGTRPVDLHLKALRAMGADITVKNGYINARCKKGRLQGKRLMFDTVTVTGTENVLMAAVLAEGITTIKNAAREPEVVDLANFLIQMGAKIRGAGTSTIEVEGVESLNGGTYSVMSDRIEAGTYLAAGALTRGQVTVKKVRPDTLLSQLCKFEEAGAELTIGEDWVSLNMHNKRPQAVNIATAPYPAFATDMQAQFMAMNSVAEGSSTIIETIFENRFMHVQELQRMGANIQLNGNTAIVHGVEKLTGAPVMATDLRASASLILAGLVAEGETVVERIYHVDRGYERIEEKLSLLGADIKRVSDR
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGD_MYCSJ
Sequence: MSSSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYNPEPTTDSSASENGQQTRTAAPKAPPEPAPAPAPKSQDSKSQAPKQDSKPQESKPQAKAKPAESKSSTKPADAKSEKSGKSGTNGAAKPAAQPADDSDQNQVLRGAAAAVAKNMSASLDVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLIGYAIVAAVKKFPNMNRHFAEVDGKPNAVTPAHTNLGLAIDLQGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTVHQLLLSDDFFDEIFRELGIPYEPVRWRTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREFKVNGFAGAERKKLRDVLAVLRDAYCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLVRAKQDLLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQIGFTTSPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDLLCYRRRGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLEQVFNEVRELEKHEIEPSESVEADQQIPAKLATAVDKSLLARIGDAHLAVPEGFTVHPRVKPVLEKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRKTGKEFTPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFINGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGDGDRNKVTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYPNVDEKFWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFAP
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle (By similarity).
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: IHFA_TOLAT
Sequence: MALTKADIAEHLFTELGISKRDAKELVETFFEDIRLALESGEQVKISGFGNFELRTKNERPGRNPKTGEDIPITARRVVTFRPGQKLKSRVEHARPVDEADDDGDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: GSHR_CAEEL
Sequence: MLRFRCILSTSRSIMSGVKEFDYLVIGGGSGGIASARRAREFGVSVGLIESGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLNKFDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAKYRGKNTLIAVGGKPTIPNIKGAEHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGLLTIKTTTGVIEKVQTLIWAIGRDPLTKELNLERVGVKTDKSGHIIVDEYQNTSAPGILSVGDDTGKFLLTPVAIAAGRRLSHRLFNGETDNKLTYENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAMKLVCVGKDEKVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTMRGGVKPE
What is the function of this protein?
Maintains high levels of reduced glutathione in the cytosol (PubMed:23593298).  Involved in resistance to oxidative stress and starvation (PubMed:23593298).  Together with thioredoxin reductase txtr-1, required for the reduction of disulfide groups in the cuticle during molting (PubMed:21199936).
What are the official names of this protein?
Glutathione reductase, mitochondrial, GR, Glutathione disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: GCH1_LEPBA
Sequence: MENLIEEILKQIGEDPNREGLVKTPNRVKKAYDFLTSGYKADINQLVNGAIFEENTTGMVLVRDIEMYSLCEHHLLPFYGRAHVAYIPNKKIIGISKIPRIVDVFARRLQVQERLTDQIAQAIQETLDPLGVGVVIKAKHLCMMMRGVEKQNSELFTSSLLGLFKTDPTTRSEFLDLIRTGSH
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: MRP7_MOUSE
Sequence: MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSALPHALLAVLSACHLGTPRTTNHSPALNPGWRLRLAASFLLSIFPLLDLLPVVLPPGSRPGPLWLEVLAGCVTAVAWFTHSLALWALVHSPHGRSRGPLALALAAFLPTPALVLTLLWHCQRGTFLPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPQEPWTHDPFLSSESQETEVAEDGESWLSRFSYAWLAPLLARGVRGELQQPRDTCRLPRRLHPAFLARVFQAHWKEGAQLWRALYRAFGCCYLALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLAGGTVISAVLQNQYGYEVRKVTLQARVAVLSTLYRKALKLGPSRPPTGEVLNLLGTDSERLLNFAGSFHEAWGLPLQLAITLYLLYQQVGMAFLAGLVLALLLVPVNKVIATRIMASNQEMLRHKDARVKLMTELLSGIRVIKFFRWEQALGDRVKACRTKELGRLRVIKYLDAACVYLWAALPVVICITIFITYVLMGHQLTATKVFTALALVRMLILPLNNFPWVINGLLESKVSLDRIQRFLDLPSYSPEAYYSPDPPAEPSTALELHEALFSWDPIGASQKTFISHLQVKKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSELSKGFGLATQEPWIQCATIRDNILFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARAVYQEKALYLLDDPLAAVDADVANHLLHRCILGVLSHTTRLLCTHRTEYLERADVVLLMEAGQLVRTGPPSEILPLVQAVPTAWAEKEQVATSGQSPSVCDLERTTEEELEVEQSTCGCLVQEESKSEGAVALHVYRAYWRAMGSGLAAAILVSLLLMQATRNGADWWLAHWLSQLKAGRNGSREDPASCSPGSTALFSPRLLLFSPGNLYTPLLSTPLHKAASNGTADVHFYLIVYATIAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSDVACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFVYYSVQGYYRASFRELRRLGSLTWSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYATMQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSFTQTEAMMVSVERLEEYSCDVPQEPHSQPLQSPHQQRISWLTQGSVEFQDVVLVYRPGLPNALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPNAGRVLLDNVDTSQLELAELRSQLAVIPQEPFLFSGTIRENLDPQGLHEDRALWQALEQCHLSEVAVAMGGLDGELGERGQNLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICKRFANKTVLTIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFQQLLQSSQQGAHSGPSGC
What is the function of this protein?
ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells.  Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4).  Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP.  May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (By similarity).
What are the official names of this protein?
ATP-binding cassette sub-family C member 10, Multidrug resistance-associated protein 7.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: ATP8_DROSI
Sequence: MPQMAPISWLLLFIIFSITFILFCSINYYSYMPNSPKSNELKNINLNSMNWKW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: PANB_THIDA
Sequence: MPVTLSTLKALRQKGEKIAVLTCYDASFARVFDAAGVDVLLVGDSLGMVIQGHASTLPVKLAEMAYHTRCVAAGTTRAFIVADLPFGSYQPSPERAYTAAARLMAAGAHMIKLEGGAVMVDTVAFLAARGIPVCAHLGLLPQSVNQLGGYRVQGREDGDAAQLVADARALEAAGAGLIVLEMVPAALAKTVTAALSMPTIGIGAGADCAGQVLVSYDMLGLYPRAPKFSKNFLAGAGSVDAAVRAYVAAVKDGSFPAAEHAF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2_HUMAN
Sequence: MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: MIG23_CAEBR
Sequence: MRVSRRFTILAITAMIFLSLIICIYAVAAHTTVNVILQKQERSYGVICDAGSTGTRLFVYNWVSTSDSELIQIEPVIYDNKPVMKKISPGLSTFGTKPDEAAEYLRPLMELAELHIPEEKRPYTPVFIFATAGMRLIPDEQKEAVLTNLRTELPKITSMQVLKEHIRIIEGKWEGIYSWIAVNYALGKFNRTFTPDFPGTSPGQQRSKTVGMIDMGGASAQIAFELPDNDDFNSINVENINLGCREDDSLFRYKLFVTTFLGYGVNEGIRKYEKTLMAKLKDQNGTVIQDDCMPLNLHKTVTMENGDNFVRRGTGNWDTCAAEVKKLLNPETSSEVCKAEVAKCYFGAVPAPNIPLSNVEMYGFSEYWYSTHDVLGLGGQYNAENIAKKSEQYCGQRWSTIQAASKKNLYPRADEERLKTQCFKSAWITSVLHDGFSVDKTHNKFQSVSTIAGQEVQWALGAMIYHMRFFPLRDSTRNLIVKETHSASESLWAPLFFLSAVFCLFVLVCAKEHSLLCFDDKRRASFGLTRRQYSYKMLKEDRTSSSAFLENFA
What is the function of this protein?
Seems to be able to hydrolyze ADP, UDP and GDP.  Supports mig-17 glycosylation and surface expression, which is required for proper migration of distal tip cells during gonad morphogenesis (By similarity).
What are the official names of this protein?
Nucleoside-diphosphatase mig-23, NDPase, Abnormal cell migration protein 23.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: SUCPP_THETC
Sequence: MALKNKVQLITYPDSLGGNLKTLNDVLEKYFSDVFGGVHILPPFPSSGDRGFAPITYSEIEPKFGTWYDIKKMAENFDILLDLMVNHVSRRSIYFQDFLKKGRKSEYADMFITLDKLWKDGKPVKGDIEKMFLRRTLPYSTFKIEETGEEEKVWTTFGKTDPSEQIDLDVNSHLVREFLLEVFKTFSNFGVKIVRLDAVGYVIKKIGTSCFFVEPEIYEFLDWAKGQAASYGIELLLEVHSQFEVQYKLAERGFLIYDFILPFTVLYTLINKSNEMLYHYLKNRPINQFTMLDCHDGIPVKPDLDGLIDTKKAKEVVDICVQRGANLSLIYGDKYKSEDGFDVHQINCTYYSALNCDDDAYLAARAIQFFTPGIPQVYYVGLLAGVNDFEAVKKTKEGREINRHNYGLKEIEESVQKNVVQRLLKLIRFRNEYEAFNGEFFIEDCRKDEIRLTWKKDDKRCSLFIDLKTYKTTIDYINENGEEVKYLV
What is the function of this protein?
Catalyzes the reversible phosphorolysis of sucrose 6(F)-phosphate into alpha-D-glucose 1-phosphate (Glc1P) and D-fructose 6-phosphate.  May be involved in a new pathway for the degradation of sucrose, which could become phosphorylated on its fructose moiety during uptake via a PTS system.  To a lesser extent, can also reversibly act on sucrose in vitro (PubMed:24599311).  Is also able to catalyze transglycosylation reactions in vitro (PubMed:26074151).
What are the official names of this protein?
Sucrose 6(F)-phosphate phosphorylase, Sucrose 6'-phosphate phosphorylase, SPP.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.
Protein: EXO_LAMBD
Sequence: MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFDEIVPEFIEKMDEALAEIGFVFGEQWR
What is the function of this protein?
Facilitates phage DNA recombination through the double-strand break repair (DSBR) and single-strand annealing pathways.  Also important for the late, rolling-circle mode of lambda DNA replication.
What are the official names of this protein?
Exonuclease.
Protein: Y1781_STRMU
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAVIGVNDHTLVTESDGRRWVTREPAIVYFHKKFWFNIIAMIRDNGVSYYCNLASPYIMDQEALKYIDYDLDVKVFADGEKKLLDVDEYELHKQKMGYSSDIDYILKENVKILVDWINNGKGPFSQSYINIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein SMU_1781.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: ERMA_STAAU
Sequence: MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Erythromycin resistance protein, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: CSBA_DICDI
Sequence: MVDLKITLVNEDGESTISGKGHPLPAPLIFPPIYIFRFTQYQTEGKLWDKNEFQIKSGKIEFDGEEYDIPESKGTWSKDDEENAIDVNLHLFRPPEKFFPKN
What is the function of this protein?
Cell-cell adhesion during early development.
What are the official names of this protein?
Glycoprotein 24A, gp24A, Contact site B protein A.
What is the protein family that this protein belongs to?
Belongs to the csb family.
What are the subcellular locations of this protein?
Cell surface.
Protein: DAPE_SHEPC
Sequence: MTAEHFPVTELAKDLISRPSVTPLDEGCQTLMAERLSAIGFNIEPMIFEDTTNMWARRGNQGPVFCFAGHTDVVPTGDISRWHTPPFEPTIIDGYLYGRGAADMKGSLAAMIVATERFVTKHPDHQGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWALVGEPSSTLKLGDVVKNGRRGSLTGNLTIKGIQGHVAYPHLADNPIHKAAPFLAELSQMHWDNGNEFFPPTSMQIANIHGGTGASNVIPGALEVMFNFRYSTEVTAEILIERVEALLKAHELDYDISWIFNGLPFLTGEGPLLDATRYAIHQVTGYDTSPQTTGGTSDGRFIAPTGAKVLELGPVNATIHKVNECVKVDDLEQLALCYEVILEQLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YIBX_ECOLI
Sequence: MEKIPIRPFSDPASIISLCRCTLENSNAPLSLLCSATNKFILSARDSADLNEKGDFMNIFKPISYIASLAPREVTLLALV
What are the official names of this protein?
Protein YibX.
Protein: EFTU_BACCZ
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKAGGAEARGYDQIDAAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYGFPGDDIPVIKGSALKALQGEADWEAKIIELMAEVDAYIPTPERETDKPFLMPVEDVFSITGRGTVATGRVERGIVKVGDVVEIIGLAEENASTTVTGVEMFRKLLDQAQAGDNIGALLRGVAREDIQRGQVLAKSGSVKAHAKFKAEVFVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIIQLPEGTEMVMPGDNIEMTIELIAPIAIEEGTKFSIREGGRTVGYGVVATIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZHX2_PONAB
Sequence: MASKRKSTTPCMVRTSQVVEQDVPEEVDRAKEKGIGTPQPDVAKDCWAAELENSSKENEVIEVKSMGESQSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPGEANFKLKLIKRNNQTVLEQSIEATNHVVSITTSGPGTGDSDSGISVSKTPIMKPGKPKADAKKVPKKPEEIAPENHVEGTARLVTDTAEILSRLGGVELLQDTLGHVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLAPTKVTQPILQTALPCQILGQTSLVLTPVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANPPLTPASDRKKTKEQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSGSLAKEQLAIAASRHGRTYHAYPDFAPQKFKEKTQGQVKILEDSFLKSSFPTQAELDRLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKKGQDVGAPNGALSRLDQLSGAQLTSSLPSPSPAIAKSQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTVKWMEQYQHQPVADDHGYDAVARKATKPMAESPKNGGDMVPQYYKDPKKLCEEDLEKLVPRVKVGSEPAKDCLPAKPSEATSDRSEGSSRDGQGSDENEESSVVDYVEVTVGEEDAISDRSDSWSQAAAEGVAELAESDSDCVPAEAGQA
What is the function of this protein?
Acts as a transcriptional repressor.  Represses the promoter activity of the CDC25C gene stimulated by NFYA.  May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells.  In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.
What are the official names of this protein?
Zinc fingers and homeoboxes protein 2, Zinc finger and homeodomain protein 2.
What is the protein family that this protein belongs to?
Belongs to the ZHX family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with EFNB1 intracellular domain in the nucleus.
Protein: LIPA_MYCA1
Sequence: MTVAPEGRKLLRLEVRNADTPIERKPPWIRVRARMGPEYTELKSLVRREGLHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGRPDRLAEVFGSRPEVLAHNVETVPRIFKRIRPAFTYRRSLDVLTAAREAGLVTKSNLILGLGETPDEVRTALADLRGAGCDIITITQYLRPSARHHPVERWVKPEEFVEFARHAEELGFSGVLAGPLVRSSYRAGRLYRQAARARA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.