PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_BUCA5
Sequence: MPIRILPSDLSSQISAGEIIERPASVVKEIIENSIDAGSKNINIIVENSGFQSIILKDDGCGIDKKDLLLAVCHHATSKINSLSDLDKLTTFGFRGEALASIRAVSRLTLISCTRFNDVAAKIYLEGFCSKNIILQPIAHPEGTTIIVDNLFYNIPVRLKFLKNKKLEFSKICEVVKKIALSHFYINFSLKHNNKLITQYNSINNRKNKINRLKDIFDTLDTSEFLEIKEKKYRMVLFGWISHPYNFKKIKNIQYCYVNNRYLYNNIFVNAVRAAYSKIEQKKNISFVLYLTIESFNIDINIHPTKNEIKFHNPDVVYTFIYEAVFSYLKKIKEKYYFNFSCKKQTQLNKEKEFYFYDSDPTFLTLISSIFFKKKQIFKNIKNKIKHNNFISKSTPLEKYESSIGRLLIIIHKYYGLIYHDNNFLLLSFPVAKGIVRKQKLKNNIQKENIIEYFLSNIKINLTSQEYLILFNKKEILSKFGFHLIFKKKYVILSSIPAFLKKCNFHIIISNFFAFLFLKKQVFISDIVDWFYINVFIELKNWTYIRGIEVLLEIEYYCPLLLINPPSKLLQKININAALCILKI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ECM1_YEAST
Sequence: MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEPEVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLANSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLNGGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEE
What is the function of this protein?
Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus.
What are the official names of this protein?
Shuttling pre-60S factor ECM1, Extracellular mutant protein 1, Protein SIM1.
What is the protein family that this protein belongs to?
Belongs to the ECM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm and is re-imported by the KAP123 karyopherin.
Protein: FRBC_BLOB1
Sequence: MVIFKSPLPVGQHQSLEVIAPVGELALNVHLALAKQHEVKPPFIDVMSGKAWHAEEIRDRVDHLARVLAKQFGWQPNVGTPWDKVVAIYSYNTVDFIILSWAVHRLGGLCLLLHSTSSAGEIAAHLKRVQCAAIFTNEPLLATTRKARELLNGEPQKIFILDVANELLPEGHVNSDLTTVEQLAQKGAELEALEPLKWDAVNGRDQVAYLCPTSGTSGAQKLAKVTHGGLLANAVQTVAHELKTNQGKTEVGLNFLPCSHIYGMMLSHTMATRGDCMVLHPFFDLKRVLGSIARFRIERLYLVPSIISALTRNPFLLDMVDLSSVTSVVTGAAPFGSSLADGLHTLRPKWHLQPGWGLTEGGGASSLTPKDDFVPGSSGVLLPLTEVRLIGEDGKDAEGHEVRGEIYMKSPSVIAGYLEDANTQNPFTEDGWLRTGDIGMFKVSPKGVEHLWVVDRVKDMIKVKGMQVAPAELEAHLLLLPQIAEVAVIGVADKISGERPKAFIVQAKNAGPEEQLRETINQHVEATLSEPHWLGKRIEFVNDLPKTSSGKAMKSVLRAKA
What is the function of this protein?
Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of the antifungal antibiotic FR901469, an inhibitor of beta-1,3-glucansynthase, exerting antifungal activity against the pathogenes Candida albicans and Aspergillus fumigatus (PubMed:27660098).  FR901469 is a cyclic depsipeptide containing 12 amino acid residues and a fatty acid chain (PubMed:27660098).  The NRPS frbI contains 12 modules responsible for the formation of the depsipeptide backbone which is denoted as Acyl-Thr-Ala-Tyr-Val-4OHPro-Thr-Thr-3OHPro-threo3OHGln-Gly-Thr-Orn-OH (C71H116N14O23) (Probable).  The PKS frbB is probably involved in the production of the hydrocarbon chain, and the acyl-CoA ligase frbC might be involved in the transport of the chain to the peptide ptoduct of frbI (Probable).  Because FR901469 contains 3 hydroxylated amino acid residues, the 3 oxygenases frbA, frbH, and frbJ might be participating in amino acid hydroxylation (Probable).  As no thioesterase domains were detected in frbI or frbB, the thioesterases frbD and frbE may instead release and cyclize the products of the NRPS and PKS, respectively (Probable).
What are the official names of this protein?
Acyl-CoA ligase frbB, FR901469 biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL36_STAA2
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YIHI_SHIFL
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: UVRA_HAEDU
Sequence: MKSIDIRGARTHNLKNINLILPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPKHDLPLVAQTISQMVDRVMQEPEGKRLMLLAPVVRNRKGEHVKLLENLTASGYIRARINGEICDLSDPPVLELQKKHTIEVVVDRFKVRSDMMSRLAESFETALELSGSTAIIADMDDPGAPEMVFSASFACSECGYSLPELEPRLFSFNNPAGACPTCDGLGVEQYFDPAKVVQNPDVSLASGAIKGWDRRSLYYFSLLTAVASYYAFDIDTPFAQLPAKIQQIILYGSSDEIEFFYINDRDDKIQRKHTFEGVLNNMARRYKETESNAVRDELAKYINNRACLACQGSRLRQEARNVFIEQANLPEIAEKSIGEALTFFEQLELNGQRAQIAEKILKEIRERLQFLVNVGLNYLSLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRDLGNTVIVVEHDEDAIRAADHIVDIGPGAGVHGGQVIAQGSATEIMQIEASITGQYLAGKQKIEIPTERIPYDANKLLILSGASGNNLKHVELVIPVGLFTCITGVSGSGKSTLINDTLFPLAQNALNRAERTDVAPYQAIDGLAHFDKVIDIDQSPIGRTPRSNPATYTGLFTPIRELFAGTQEARARGYNVGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDHCKGKRYNRETLEVRYKGKTIHQVLEMTVEEAREFFDAIPAIARKLQTLIDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLAVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGAGGGQIIAQGTPEDVAQQPGSHTARFLTQILAKG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYL1_PACTA
Sequence: MTLQYYTLNNGRKIPAIGMGCWKLENAADMVYAAIKEGYRLFDCACDYGNEKEVGEGINRAIKDGLVKRKDLFITSKLWNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIKPASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNFGPLSFLELGNETAKKTQPLYENKTITTIAAKHGKTPFQVLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEIAKLDRHLRFNDPWTWDKIPTFV
What is the function of this protein?
Reduces D-xylose into xylitol.  Has a preference for NADPH, but can also utilize NADH as cosubstrate (By similarity).
What are the official names of this protein?
NAD(P)H-dependent D-xylose reductase, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: NEMS_HEMMO
Sequence: QDVDHVFLRF
What is the function of this protein?
Myoinhibiting neuropeptide.
What are the official names of this protein?
Myosuppressin, MS.
What is the protein family that this protein belongs to?
Belongs to the myosuppressin family.
What are the subcellular locations of this protein?
Secreted.
Protein: T23OB_DANRE
Sequence: MSGCPFLGGTLQLLSSNPRQAEEEDGSQGGVNKAAKGGIIYGDYLQLDKVLNAQVLQSEQKGNKIHDEHLFIVTHQAYELWFKQILWELDSVRDLFIKKHVRDERNMLKVVSRIHRITMIFKLLVDQFAVLETMTALDFFDFREYLSPASGFQSLQFRLLEQKIGVADHLRVPYNRRHYRDNFHGEESETLLSSEQEPTLLQLVEQWLERTPGLEKDGFNFWGKLQANIEEGLKREKHQVEKMEDTEVKQELLEDLNKQMETFTALFDSKRHEHLLSKGERRLSYKALQGALMINFYREEPRFQVPFQLLTALMEIDTLMTKWRYNHVCMVHRMIGSKAGTGGSSGYHYLRSTVSDRYKVFVDLFNLATFLVPRSWVPKLNPNIHKFPYTAECYDSSYNSCSSEDSD
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase B, TDO-B, Tryptamin 2,3-dioxygenase B, Tryptophan oxygenase B, TO-B, TRPO-B, Tryptophan pyrrolase B, Tryptophanase B.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: LPXH_SHESW
Sequence: MRTLFIGDLHLSADRLDITQAFTHFLDTELDDADALYILGDLFEVWVGDDIAAPFALELANKLKQVSLKLPVYFIHGNRDFMLGKQFARAAGMQILPEVTCLNLYGVKTVILHGDSLCTLDKAYQRFRKLRSLALARWLYGCLSKKTRQGIADNIRSKSKSSNKHKSYTIMDVEPNAVNALLARTHAQYMIHGHTHRPAIHQLDNGCKRIVVGDWYQQGSVLSVSPQGIDLQSLPFSPQQD
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL19_HAEI8
Sequence: MSNIIKQLEQEQLKQNVPSFRPGDTLEVKVWVVEGSKRRLQAFEGVVIAIRNRGLHSAFTLRKVSNGVGVERVFQTHSPAVDSIAVKRKGAVRKAKLYYLRERSGKSARIKERLGA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL16_STAAC
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YAFD_ECO27
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2H_LATSE
Sequence: MNPAHLLVLLAVCVSLLGASAIPPLPLNLVQFSNMIKCTIPGSRPLLDYADYGCYCGAGGSGTPVDESDRCCQTHDNCYSQAKKHPACKSPLDSPYIKIYSYTCSGGSLTCRDDNDECGAFICNCDRTAAICFAGAPYNKENYNIDTKKHCK
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 pkP2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PKS18_MYCTO
Sequence: MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQSDAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPATIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPGVDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVVCIELCSVNAVFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVVRSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWDNGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLSVSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR
What is the function of this protein?
Involved in the biosynthesis of tri- and tetraketide alpha-pyrones.  Pks18 catalyzes the extension of medium- and long-chain aliphatic acyl-CoA substrates by using malonyl-CoA as an extender molecule to synthesize polyketide products.
What are the official names of this protein?
Alpha-pyrone synthesis polyketide synthase-like Pks18, Alpha-pyrone synthesis polyketide synthase type III Pks18, Chalcone synthase-like protein, CHS-like.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: EIF3C_PICGU
Sequence: MSRFFVSGYDSESSSEEEDLLTSSEEELMSSEQESDSEFDDEFANDDDSDSSDSDSDGRPSGPAYFLKSSFRKGAGGDSDSDSEDEGRRVVKSAKEKLTDDMKDAVEAVNSAKRQENWISALTEFERLGRLLVRAGQQGFGTPNFYIKCLVDLEAYLIETTANEKESTRKMNANLARAFTSLKQRVKKQVKEFSHLVELYKSEPELFDKEEPVETIEKDAEIQATPLASSTGRALSPVFATLKSVAETRGKKNIDKFEQVQILEDLLEEVSPKGSPFEIISIYQMLLSIRFDASSHHAFMPLDQWQKNKDTLNDLLDFLEKHSNEYQVSELGTASDDIDLEPPANADGIRILPGSVTSHIERLDDEFIRYLQNTDPHSLEYIDRLKDEKDTYNLVVRGQLYVEKTTPDHVRGTYQGEQLARIVMRRMNHIYYKPDQLIKANESEAWRHLSGDSQIVAKNSEPKDVINGLAEFLSKQDGAIYPKGALLFSVYYHAVNNDYSVARDMFLSSQVHQGINNADSSIQVLYNRAMVQLGLSAFRYGNIEESHQALNEIANSQRLKELLGQGFNSKYPSQATVAEKQRLLPFHMHINLELLECVFMTCSLLIEIPQLAAASNSTKESRRKTNIKSFKSKLEFHDRQYFTGPPESIKDHIVHASISLQKGDWHNAYKLLSTIKIWKLLPNNDQLLEMMRGKLQVEGLRTYIFTYKSIYTKLSVVKLAKIFDINEEEVLSIVDKMISSGEVSASLSDDKKSINFVSSEHLQRTRLQELAIVMNEKIGLLTDKNEKTASNGHGRKTTQQQQQQQQKEQREQTHDENIKFRYANVNTNNDEFQTIA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_ANTOD
Sequence: MSRYRGPRLKKIRRLGALPGLTRKTPKSGSNLKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVHIAGKAKRSTGQVLLQLLEMRLDNTLFRLGMASTIPGARQLVNHRHILVNGRIVNIPSFRCKPRDIITTKDNQRSKDLVRNSIASSDPGKLPKHLTIDTLEYKGLVNKILDRKWVGLKINELLVVEY
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHMC_PHANO
Sequence: MLSSILLTIFCAFLSSTGAANVADWNSLNKTLKGQLKGATPLASPCFSQVNAYEETQSEDCATAIGQQCLLDSSDPSSIKAYANVSCNQGSVPSYYIQVKSAEEVKKAFAFAARTQTAISIKNSGHDYNGRSSGAGSLSLWTRKLQELKYEPSFVPQQCGRQAGVAAITTGAGINFDQVYTFAHEKGVTYLGGSGPTVGASGGWVMTGGHGVLSRVYGLGVDRVLEFEVVTTDGVTRIANACQNQDLFWALRGGGGGTFGVILSTTTRVEPKLSIAVAFIALPANTSQQVLAEWTSLAINSTIKWAADGWGGFQGSGITLLGTPLLSLAQAESSMAELAQFAKRNGGSVAVELLSDFYDMYTKYYITNVQAGGSALFSHNWMIPSRAYANAQGRKQLQDHMDWMSSVGLNPGFLATTPYVYSGVAKQCGTFDAFGWMGL
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities (PubMed:31815421).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS phmA, assisted by the enoyl reductase phmE, that are responsible for fusion of the leucine precursor and the polyketide backbone to produce a 2-pyrrolidone intermediate (PubMed:31815421).  The polyketide synthase module (PKS) of phmA is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the leucine precursor (PubMed:31815421).  Because phmA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase phmE (PubMed:31815421).  Reduction by the hydrolyase phmG, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase phmD then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase phmB, the FAD-linked oxidoreductase phmC and the short-chain dehydrogenase/reductase phmF, are further required to afford the final products, phomacin D and phomacin E (PubMed:31815421).
What are the official names of this protein?
FAD-linked oxidoreductase phmC, Phomacin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: TPIS_RABIT
Sequence: MAPSRKFFVGGNWKMNGRKKNLGELITTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALSEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP9_SOYBN
Sequence: MLEGAKSIGAGAATIASAGAAVGIGNVFSSLIHSVARNPSLAKQLFGYAILGFALTEAIALFALMMAFLILFVF
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PFLA_STAAR
Sequence: MLKGHLHSVESLGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKISEPSREVTVDEMVNEILPYKPYFDASGGGVTVSGGEPLLQMPFLEKLFAELKENGVHTCLDTSAGCANDTKAFQRHFEELQKHTDLILLDIKHIDNDKHIRLTGKPNTHILNFARKLSDMKQPVWIRHVLVPGYSDDKDDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKTLGIAYELEDVEAPDDEAVKAAYRYVNFKGKIPVEL
What is the function of this protein?
Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Pyruvate formate-lyase-activating enzyme, PFL-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZWILC_BOVIN
Sequence: MWSGANRAAEEFYAGLLQEFDENKKGIRKDPFIYEADIQVQLISKGQPNPLKNILHENETIFIVEKVPLEKEEPSPIEELQSEDTAISDLSTGENVGLLALPIGRARQLIGFYTMAHNPNMTHLKINRPVTALPPLWVRCDGSDPEGISWLGAELISTSSNITGIVLYMVTCKVDKNYSVNLEDLKKSHKKRHHLSTLTASGFARYELFKSTALDDTVAASQTTITLDISWSPVDEILQTPPLSSTATLNIKVESGEPRGPLSQLHRELKFLLVLADGLRTGVTEWPEPLEAKSAVELVQEFLNELSKLNEFGDSTKKDTEIVKHDAAAVDGSIECLLTVRGDLDFAEQLWCKMSSSVISYQDLVKCFSLVIQSLQRGAIQPWLHSGSNSLLSKLIHQSYYGTMDTVSLSGTVPVQMLLEIGLDKLKKDYICFFIGQELASLNHLEYFISPSVDTQEQVHRVQKLHHILEIVVSCMLFIKPQHELLFSLTQSCIKYYEQNPLDEQHIFQLPVRPTAVKDLYQNEKPQKWRVEINSGQKKVKTVWQLSDSPPIDHLNFHRPDFSELTLSGSLEERISFTNMVTCSQVHFK
What is the function of this protein?
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.  Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.  Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (By similarity).
What are the official names of this protein?
Protein zwilch homolog.
What is the protein family that this protein belongs to?
Belongs to the ZWILCH family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: FETP_XANAC
Sequence: MSRTVFCHYQQSDAEGLDFVPYPGELGQRIFAQIGKNAWQAWLAHQTMLINENRLSPRDPKHRAFLEAELQKFLFERNADKPEGYVAPVGD
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: AROA_METMJ
Sequence: MIVRVSQTGPVDAAFPAPPSKSYTHRALIAGALALGRTRIARPLRAADTELTARGLEALGVPLEWLPGEIAVAGCSGTFPAAGEVTIDCGNSGTTLRLLTSAALLSQHPVVLTGSPRMLERPVGPLAGALRALGGDVAFTGQPGYPPIRISGRLRGGRATIDGSISSQFVSSILMAAPYAEEDVELTLPATPASRSYLDVTADVMLRFGAHIERQGYDRFRVESGRAYRGRDYRVEGDYSSASYLFAVAAVCGGRVAVTGLNPTSVQGDRRFLDALEAMGCSVAAGTDAVTVERTGDLKGIEIDMSSSPDTVQTLAAVAATAGSPTTITGTAHLQYKESDRVGVTADTLRRMGAGVEVTEDSLTITPAPLHGVAVDPHDDHRTAMAFAVLGLAVGGMAIRDPECVEKSFPGFWEALYGEGLL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_METJA
Sequence: MSDLENIDYYDYKALLKRARSQIPDYVFQKDRFELPEIEILIEGNRTIIRNFRELAKAVNRDEEFFAKYLLKETGSAGNLEGGRLILQRRISPELLKSRINDFLREYVICRECGKPDTKIIKEGRVHLLKCMACGAIRPIRMI
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: PRDC1_HUMAN
Sequence: MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV
What is the function of this protein?
Has low, barely detectable phosphoribosyltransferase activity (in vitro).  Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP).  Is not expected to contribute to purine metabolism or GMP salvage.
What are the official names of this protein?
Phosphoribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: SCP1_ARATH
Sequence: MANKYVSSVLKSLLVLLHLVFLSKQHVDSASIVKSLPGFEGQLPFELETGYIGVGEEEEVQLFYYFIKSERNPKEDPLILWLTGGPGCSAISGLLFENGPLTMKLDVYNGTLPSLVSTTYSWTKTSSIIFLDQPVGTGFSYSRTQQFNKPSDSGEAKRIHEFLQKWLGKHQVFSSNPFYVAGDSYSGLVVPATVQEISKGNYECCNPPINLQGYVLGNPLTDYTTGSNSRIPFAHGMALISDELYESLKKTCKGEYTNVHPRNTQCLKFVEEFNKCTNRIFQQLILDPLCETETPDCYIYRYLLTTYWANDATVREALQINKESIGEWVRCYYSIPYNNDIKSSMPYHVNNSISGYRSLIYSGDHDFEVPYLGTQAWIRSLNYSIIDDWRPWMVKNQIAGYTRTYANKMTFATIKGGGHTAESKPEEASIMFQRWINGQPL
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_SERP5
Sequence: MARYFRRRKFCRFTAEGVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARCIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.