PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_LARHH
Sequence: MSDFRQDFIRFAVEEQVLRFGEFVTKAGRPSPYFFNAGLFNHGASLLSLARFYARSISESGIAFDMLFGPAYKGIVLAGATAMMLAEQGRDVPFAFNRKEAKDHGEGGTLIGAPLKGRVLIIDDVISAGTSVRESVEIIRANGAEPAGVAIALDRMERGQGELSATQEVAQKFGLPVVAIASLDDLLGFLAGSPDLADNLTRVEAYRTQYGVR
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PYRR_RALSO
Sequence: MTSQQIDAEALYQSLVAQLRTRMAGTPAGDWSVAGIVSGGAWIAARLALDLGLREYGIVNVALHRDDYAKKGLHAQAQPTTLPFEVEERRILLVDDVLATGRTIRAAINELFDYGRPAAVELAVLVDRGERQLPIAPDYIGERIALAADESLVLRQEGEGASARFTFTREPKTA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PSD1_BOVIN
Sequence: MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLLRRVAGPGPRSRELGRVTAPCTPLRGPPSPRIAPSPWAPSSPTGQPPPGARSSVVIFRFVEKASVRPLNGLPAPGGLSRSWDLGGVSPPRPTPALGPGSHQKLRLEASTSDPLPAGGGSARPGTQGLLQGPPTQPQVGADGLYSSLPNGLGGPSEHLATLFRGPADTGLLNQGDIWSSPREVSSHAQRIARAKWEFFYGSLDPPSSGAKPPEQAPPSPPGVGSGQGSGVAVGRAAKYSETDLDTVPLRCYRETDIDEVLTEREEADSAIESQPSSEGLPGTARPPAPRPGPCLGPHPSLGSGNEDEDEAGGEEDVDDEVFEASEGARPGTRMPHSGPLKSPLPFLPGTSPSADGPDSFSCVFEAILESHRAKGTSYTSLASLEALASPGPTQSPFFTFELPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRGEEEEAEAGAKQTPGRDPPSPCHSEDSFGLGAAPLGSEPPLNQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPGALSSEDGAHTLTCALMLLNTDLHGHNIAETHDLRRLHRYLEGLNEGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSGSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKNFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRATQLTKKARGKEAEEQRQKEAYLEFEKSRYGTYAALLRVKLKAGSEELDAVEAAVAQAGGTEDGLPPPHSSPSLPANTSSQPRAQCSDSEARAGAGSGRWKP
What is the function of this protein?
Guanine nucleotide exchange factor for ARF6 (By similarity).  Induces cytoskeletal remodeling (By similarity).
What are the official names of this protein?
PH and SEC7 domain-containing protein 1, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, Exchange factor for ARF6, Exchange factor for ARF6 A, Pleckstrin homology and SEC7 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PSD family.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, ruffle membrane. Cleavage furrow. Note=Distributed uniformly on the plasma membrane, as well as throughout the cytoplasm during metaphase. Subsequently concentrated at patches in the equatorial region at the onset of cytokinesis, and becomes distributed in the equatorial region concurrent with cleavage furrow ingression. In later cytokinesis phases, fades away from the cleavage furrow and becomes uniformly distributed throughout the plasma membrane.
Protein: YRAN_SALG2
Sequence: MAQIPARGDCSRQLTRKQAGDAWEAAARRWLESKGLRFIAANVRERGGEIDLIMRDGKTTVFVEVRYRRSGLYGGAAASVTRSKQHKLLHTARLWLARQNGSFDTVDCRFDVLAFTGNEIEWFRDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CH10_ACTPJ
Sequence: MTLRPLHDKVILKREEVETRSAGGIVLTGSAATKSTRGKVIAVSTGRLLENGSVQALAVKAGDVVIFNEGYGVKSEKIDGEEVLILSENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXPA5_ARATH
Sequence: MGVLVISLLVVHLLAFSVCVQGGYRRGGHHPGGHMGPWINAHATFYGGGDASGTMGGACGYGNLYSQGYGLETAALSTALFDQGLSCGACFELMCVNDPQWCIKGRSIVVTATNFCPPGGACDPPNHHFDLSQPIYEKIALYKSGIIPVMYRRVRCKRSGGIRFTINGHSYFNLVLVTNVGGAGDVHSVSMKGSRTKWQLMSRNWGQNWQSNSYLNGQSLSFVVTTSDRRSVVSFNVAPPTWSFGQTYTGGQFRY
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A5, AtEXPA5, Alpha-expansin-5, At-EXP5, AtEx5, Ath-ExpAlpha-1.4.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: GLBW_CHITP
Sequence: MKFLVILTLCIAGAIAHCDKAPFIKASWNQVKHNEVDILYTVFKAYPEIQDRFPQFAGKDLEAIKETAEFAVHSTRIVSFMSEIVSLVGNPAVQSSIDLLLVKMANDHKARGVTKELFEKFNIAFMGYLKSHTTWDEKTENAWKVVGDEHHAIVYSILE
What are the official names of this protein?
Globin CTT-W, HBW.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: KDKA_PHOPR
Sequence: MEELCFDNQRIWFDPNLLQEDPKACFDASFWQQQGKVIGSAQGRGTTWFVQGETLPMALRHYRRGGLFGKLIEDAYVFTGWEKTRCAEEVALLSTLAVGGVNVPRPVAARATRHGLVYRADLLVEKIDSAKDLVDLLQQAMLPDHVWYAIGRTVRKMHDLQVCHTDLNAHNILVDSRELVWLIDFDKCYTQEGEAWKAKNLSRLHRSFVKEQGKRNIHFSATSWQVLCQGYELPDN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EX7L_LACDA
Sequence: MDSIKGTDEKYLTVSELNWYVKQKFDRDPYLRQIFLQGELSNFRFRRGGHQYFSLKDDKSKINVVMFRGDFDKVKFEPEEGMKVYVTGRLSTYEAQGSYQFYAKSMEPAGLGALYERFRQLQEKLAKEGLFAQEHKRPLPLFPDKIAVVTSASGAVIHDIMVTANRRFSHAEIDLFPAQVQGESAAGSLVSAMQQIQARADEYDVLIIGRGGGSLEDLWPFNEEEVVRQVYAMKMPVISSVGHETDTTLCDLAADCRAATPTAAAEMATPALPLVLAEIGQLQTRLLTDIRAVIQVRAQALAQLENSFIMKEPQRLYEQKMQQVDQLSQQLSRMMEVIVKDQGQKLSLLTQRLQHQAPDRRIKQLKQENSYLAKSLEMGIKRILEQKQAACRQAVQQLDDYSPLKTLARGYSYTTDASGNVVKSVQQLVPGDQVRLHLKDGQAIGRIEEIKEEKND
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX21_HUMAN
Sequence: MHRGTQEGAMASRLLHRLRHALAGDGPGEAAASPEAEQFPESSELEDDDAEGLSSRLSGTLSFTSAEDDEDDEDEDDEEAGPDQLPLGDGTSGEDAERSPPPDGQWGSQLLARQLQDFWKKSRNTLAPQRLLFEVTSANVVKDPPSKYVLYTLAVIGPGPPDCQPAQISRRYSDFERLHRNLQRQFRGPMAAISFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRRAQSLTCTGLYREALALWANAWQLQAQLGTPSGPDRPLLTLAGLAVCHQELEDPGEARACCEKALQLLGDKSLHPLLAPFLEAHVRLSWRLGLDKRQSEARLQALQEAGLTPTPPPSLKELLIKEVLD
What is the function of this protein?
Binds to membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(P3)) and phosphatidylinositol 4,5-bisphosphate.  May be involved in several stages of intracellular trafficking.
What are the official names of this protein?
Sorting nexin-21, Sorting nexin L, SNX-L.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RT31_ORYSJ
Sequence: MAMRLAAAAAFVRRLVPARNPVISAEAEAVTCGRGDKKTKRGKRFKGSYGNARPKREKKIERIKDRVEVPRSTPWPLPFKLI
What are the official names of this protein?
30S ribosomal protein S31, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bTHX family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y3192_KLEP3
Sequence: MMYHIPDVLSADQVAEFTRQLAQAEWVDGRVTVGNQGAAVKQNQQIDTRTPLYARLQAAVLDALRGHPQFFSAALPRTISAPLFNRYGPGETYGFHVDGAVRQNAEAGWMRTDLSATLFLCDPESYEGGELVIEDTYGQHRVKLPAGHLVLYPASSLHCVTPVTHGVRQASFLWIQSMVRDDKQRATLYDLDRTIQSLKARFGDGEEVLSLLNMYHNLLRQWTEV
What are the official names of this protein?
PKHD-type hydroxylase KPK_3192.
Protein: PLSX_FRAP2
Sequence: MGYKISIDAMGGDNGLNTTIPAALEAVKKDSNLQIVLVGDHHKVKRALDRYSKVKKIKLPVLQRIAIHHASETVGMDESPSIAVRKKKDSSMRVAINLVKDGTVDACVSAGNTGALMATSKFVLKTVNGVDRPAIVYALPAFNRDTKQLSKTYMLDLGANVVCSSEQLFQFAIMGSILAASSKGLAEPRVSLLNIGEEEMKGLDNIKNASKLLQGCDFINYQGYIEGKHIFDDTTDVIVCDGFVGNVSLKTMEGSLRLIESLIKKSITETSLLMKIPVIMSLPLFKKMKKGMNLDSFNGASLLGLTGIVVKSHGSASANAFETAIYEAVKEIKHNIPKTIQESLEKVL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RR8_GUITH
Sequence: MTNDTVSDMLTRVRNANLAKHQVVQVPATKMTKSIAHVLLEEGFIESIEEVGLDINRQLLLSLKYKGREREPVINALKRISRPGLRVYANRKELPRVLGGLGIAVISTSKGVLTDTKARTQGLGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYY_MYCGE
Sequence: MLNNILQFLKERELYSQANFETELDNHLKEKKNNFYVGFDPTANSLHIGNYVLIHIAKLLKDMGHTPHIVLGSATALIGDPTGRIELRKILEEKEIVKNTKTIKKQIKQFLGDVIIHENKVWLEKLNYIEVIRELGAFFSVNKMLSTDAFSARWEKGLTLMELNYMILQAYDFYYLHKNHNVTLQIGGSDQWANILAGANLIKRKNNASVFGLTANLLVKANGEKMGKTSSGALWLDENKTSVFDFYQYWINLDDQSLKKTFLMLTMLDKKVIDELCNLKGPKIKQTKQMLAFLITELIHGTKKAKEAQQRSELIFSNQPDLDIKLVKTSTNLIDYLVETKFIKSKSEARRLISQKGLTINNKHVLDLNQIIEWKEELQIIRKGKKSFLTIKTVNS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_ERWT9
Sequence: MKKVLITAFEPFDGERINPSWEAVSRLHNRLIGGAEIVAKRLPCAFGTSLEVLYATIDAVKPDLVIAVGQAGGRADMSIERVAINVDDARIPDNAGAQPIDEPVLSGGPAALFSTLPIKALVAGIREAGIPASVSQTAGTFVCNHVMYGLLHYLRRRKARGGFIHIPYLPEQAINHPGAPSMALATVILALEMAVSISLAVEEDMRLAGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITG_LACPL
Sequence: MDTKIIVNHALRALLYEVTVNPKPGLVDPLSAGPHPDMNAFMFIDSALSLAPYFNACAAAGVAYTAVDLTGLFKQIRGIGVQAEQTMFAATKGVNTHKGAVFSLGVLVTAAAYQLQHPDVDLATIVRTMLAGLTANDFNDLNTKDPTTLTAGERQYLTYGIKGIRGEAEAGYPTVMQVALPALRRSRGTINQRLLDTLMAIVQATVDTNLVKRAHDPHVIDWVHDQAHRYFDLGGSRSEAGMAFLRELNQIFVDHNYSLGGSADLLILTIFIGLQTDILA
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: MARH8_BOVIN
Sequence: MNMPLHQISAIPSQDATSARVYRSKTKEKEREEQNEKTLGHSMSHSSNISKAGGSSVASAPVSSFPRTSVTPSNQDICRICHCEGDDESPLITPCRCTGSLHFVHQTCLQQWIKSSDTRCCELCKYEFIMETKLKPLRKWEKLQMTSSERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIRQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWRRLKAYNRVIYVQNCPETSKRNIFEKPALPEPNFESKDGRGVCHSDTNSSCCTEPEDTGAEIIHV
What is the function of this protein?
E3 ubiquitin-protein ligase that plays several important roles in innate immunity and adaptive immunity.  Mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.  Possesses a very broad antiviral activity by specifically inactivating different viral fusion proteins.  Targets and ubiquitinates cytoplasmic lysine residues of viral envelope glycoproteins with single transmembrane domains leading to their lysosomal degradation.  Mediates the regulation of constitutive ubiquitination and trafficking of the viral restriction factor BST2 within the endocytic pathway.  Plays a role in maintenance of immune tolerance to self by promoting the turnover and proteasomal degradation of PD-L1/CD274 via ubiquitination.  Catalyzes the 'Lys-63'-linked polyubiquitylation of cGAS thereby inhibiting its DNA binding ability and impairing its antiviral innate immunity.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF8, Membrane-associated RING finger protein 8, Membrane-associated RING-CH protein VIII, MARCH-VIII, RING-type E3 ubiquitin transferase MARCHF8.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: RS5_SHESW
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKIGYGYGKAREVPAAIQKAMEKARRNMVTVELNAGTLHHPVKGRHTGSRVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NUOI_YERPY
Sequence: MTLKELVVGFGTQVRSLWMIGLHAFHKRETLMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAEQKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKQKGEAENEAKPIDVKGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYD_PYRFU
Sequence: MLRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFVWIRDREGIVQITAPKKKVSEEIFKLIPKLNSEDVVVVEGIVNFTPKAKLGFEIIPEKFEILNRTQTPLPLDPTGKVKAELDTRLDNRFIDLRNPKVMAIFKIRSNVFRAIREFFYNEGFIEIHTPKIIATATEGGTELFPIKYFENDAFLAQSPQLYKQIMMATGLDKVFETAPIFRAEEHNTTRHLNEAWSIDAEIAFIENEEEVMDVLENLVVYAINYVREHNERELKILEFELEEPKQPFPRVTYDKALEILSDLGKEIPWGEDIDTEGEKLLGKYMSENEGVELYFIYKYPSEAKPFYIMKYDEKPEICRAFDLEYRGIEISSGGQREHRYEVLLEQIKEKGLNPESFEFYLKAFKYGMPPHGGFGLGAERLIMRMLNIGNIREVILFPRDRKRLIP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA(Asp) ligase, Aspartyl-tRNA synthetase, AspRS, Discriminating aspartyl-tRNA synthetase, D-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EA87_VICFA
Sequence: MEFAHLTVLSLFCLAFVGITATSPREDYWQSIWPNTPLPKTFSDMLIPSGKTNSLPIKSEELKQYSTLFFEHDLHPRKNFILGNTNSVGSIIRPFTKSRQGVTDSIWLANKEKQSLEDFCYSPTAIAEHKHCVSSLKSMIDQVISHFGSTKIKAISSNFAPYQDQYVVEDVKKVGDNAVMCHRLNFEKVVFNCHQVRDTTAYVVSLVASDGTKTKALTVCHHDTRGMNPELLYEALEVTLGTVPVCHFIGNKAAAWVPNHTADNLCVM
What are the official names of this protein?
Embryonic abundant protein USP87.
Protein: PHNW_RHIME
Sequence: MGEPYLLTPGPLTTAFSVKDAMLRDWGSWDGDFRGMTAELRRELLAIAGDESGQYDCVPMQGSGSFSVEAMLGSFIPRDGKVLVLMNGAYGQRIAQTLKYLGRAHVSIDKGDYMPPRGSEVAAALDADPAITHVVVVHCETSSGILNPLKEISEAVYSRGRKLLVDSMSAFGAVPAGVGDFRYEAIVSSANKCIEGVPGFGFVIARKSELEAAKDRSHSLSLDVHAQWAYMNKTGQWRFTPPTHVVAAFLEALRLHRKEGGVAGRGARYANNRDVMVAGMRQLGFETLLGDEWLSPIIVTFFSPAHPNFKFERFYELMKARGFIIYPGKLTVVDSFRIGCIGQMDSHVMQKVVAAAAESLAKMRVDTATPPALALAERARLAA
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: YAJC_HELPY
Sequence: MGQIKDILTTLLPLVVLFLIFYFLIVRPQRQQQKKHKEMIESLTKGDKIVTQGGLIVEVLKAEANFFSVKLNDDTTAKLSKNYVAFKLDELDQFGLAEPIVIQQGREEISAKLSGAKTLKQRQITTE
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LSRG_YERPS
Sequence: MHVTLVEINVKEDKVDQFIEVFRANHLGSIREAGNLRFDVLRDEHIPTRFYIYEAYTDEAAVAIHKTTPHYLQCVEQLAPLMTGPRKKTVFIGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THB_RAT
Sequence: MTPNSMTENRLPAWDKQKPHPDRGQDWKLVGMSEACLHRKSHVERRGALKNEQTSSHLIQATWASSIFHLDPDDVNDQSVSSAQTFQTEEKKCKGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKSLHPSYSCKYEGKCIIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGQVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SETB1_DROME
Sequence: MSGQPTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATGSTRKQCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSVELIESPVKFSSANESEKDPPKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQEPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVELEKGTAPKAAEDEKLNALLSDGDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSDEEEEEKQPEKSDFSKNKLQLIEDELDDAIKNVLNKVDFTAQLSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYNSCPVAHKHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGNTMKSYKIRYLNTPYQMIKTVTAKHIAYFEPPPVRLTIGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAASRDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMNSSSAQQLRVPRRTEPFIRYTKEMESSSKVNQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNNSTIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLFKIVHRLDSYSPLAKPLLSGWERLVMRQKTKKSVVYKGPCGKSLRSLAEVHRYLRATENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVDHSDPDAEEDNGGPDAEDDDDFRPNYHYQRKIKRSSRSGSTQNSSTQSSELDSQERAVINFNPNADLDETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 in ovary.  H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones.  Plays a central role during oogenesis.
What are the official names of this protein?
Histone-lysine N-methyltransferase eggless, SETDB1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL3_THET8
Sequence: MKGILGVKVGMTRIFRDDRAVPVTVILAGPCPVVQRRTPEKDGYTAVQLGFLPQNPKRVNRPLKGHFAKAGVEPVRILREIRDFNPEGDTVTVEIFKPGERVDVTGTSKGRGFAGVMKRWNFAGGPDSHGAHKIHRHPGSIGNRKTPGRVYKGKKMAGHYGAERVTVMNLEVVDVIPEENLLLVKGAVPGPNGGLVIVRETKKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.