PharMolix/UniProtQA huggingface dataset:
Protein: RHOB_HUMAN
Sequence: MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQNGCINCCKVL
What is the function of this protein?
Mediates apoptosis in neoplastically transformed cells after DNA damage.  Not essential for development but affects cell adhesion and growth factor signaling in transformed cells.  Plays a negative role in tumorigenesis as deletion causes tumor formation.  Involved in intracellular protein trafficking of a number of proteins.  Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.  Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.  Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.  Required for genotoxic stress-induced cell death in breast cancer cells.
What are the official names of this protein?
Rho-related GTP-binding protein RhoB, Rho cDNA clone 6, h6.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus. Cleavage furrow. Note=Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Protein: NUOH_BRUO2
Sequence: MEGIFAAYVLPALIIALKSVVLLVVLLIVVAYLLYADRKIWAAVQLRRGPNVVGPWGLFQAFADLLKFVFKEPIIPSGANKGVFLLAPFISAVLAMATWAVIPVNESWAVANINVGILYIFAISSLEVYGVIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLTVGSLNLTDIVLSQNTGLGTMLGLPASFLDWNWLCLFPMFVVFFISALAETNRPPFDLVEAESELVAGHMIEYSSTPFLLFFLGEYVAITLMCALMTVLFLGGWLPPVDVWFLSWVPGIIWFMLKLCFCFFLFAMVKAFVPRYRYDQLMRLGWKVFLPISLFMVVATATFLKVFGLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDI_SALTY
Sequence: MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCGVPWLYRFELMGTQRDIDNVRKGVNEFWQQLPRSA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: LIPB_RALSO
Sequence: MIPIDIVERGQQDYTACFDAMQTFTAQRGPDTPDTIWLVEHPPVFTLGLAGDPAHLLAPGNIPLVKVDRGGQITYHGPGQVVAYLLLDLRRRGLFVKALVDAIEAAVIDTLATYNVASERKAGAPGIYLSAGPHQGAKIAALGLKIRNGCSYHGVSLNLAMDLSPFTQINPCGYAGLETVDMVTAGARDASGRAVDAADWQRVSHVLADRLVAQLQHRANAHPAEAATA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_CHLAA
Sequence: MSIAHIVDWRLYVVTDAGLSRGRSHRAVIEAAIVGGATVVQYREKHASTRQMIEEALELRDLTRRAGVPLIVNDRVDVALAVDADGVHVGQDDMPVALARRLIGNKLLGVSAHNLSEALQAVRDGADYLGVGPIFATTTKPDAAAPIGLDGLRAIRQHVSIPIVAIGGINQANAADVMRAGADGIAVVSAVVAADDVTAAARQLRALVSVTQEKAL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: KSA_PEA
Sequence: MFTHFSTHFHLPSSSSLFFLHPFYKSSSLGAVSFVAKDKEKRCRAISKSRTQEYEGVFQTNVATLKLSEINVEDVIVIDDEEEQDIRVGLVNKIKSILSSLEDGEITISAYDTAWVALVEDVNAISTPQFPSSLEWIAKNQLQDGSWGDSRLFSAHDRIINTLACVIALRSWNMHSEKCDKGMIFFRENLSKLENENEEHMPIGFEVAFPSLLEGARGIKPLMCPNDSPILKNIFEKRDEKLTRIPKEIMHKVPTTLLHSLEGMSGLDWKQLLKLQSQDGSFLFSPSSTAFALMQTKDGNCLKYLNNVVKKFNGGVPNVYPVDLFEHIWVVDRLERLGISRFFRHEIKDCMNYVSKIWSEKGICWARNSNVQDIDDTAMAFRLLRLHGHQVSAHVFKHFERNGEFFCFAGQCTQAVTGMYNLFRASQVLFPGEKILEHAKHFSAKVLKEKREANELIDKWIIMKNLPEEVGYALDMPWYANLDRIETRFYIDQYGAESDVWIGKTLYRMAYVNNNNYLELAKLDYNNCQAQHLIEWNVIQTWYLESRLGEFGLSKRDLLLAYFLATGSIFEPERSHERLAWAKTTALLETIKCYVRNEDLRKDFAKKFNDHIDVRDYSIARRMKRNKTEHELVESLFATIGEISWDVRLSYGHEIGYDMHQCWKKWLSSWQSEGDKCEGEAELLIQIINLCSNHWISEGPSMQSTIQHLLQLTNSICHKLSCYQKDKELKGISCQENITNSEVESKMQELVQMVFQKCPNDIDFNVKNTFFTIAKSFYYAAFCDSRTINFHIAKVLFEKVV
What is the function of this protein?
Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate.
What are the official names of this protein?
Ent-copalyl diphosphate synthase, chloroplastic, Ent-CDP synthase, Ent-copalyl diphosphate synthase, Ent-kaurene synthase A, KSA.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TNNT1_HUMAN
Sequence: MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, slow skeletal muscle, TnTs, Slow skeletal muscle troponin T, sTnT.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.
Protein: HIS3_BRASB
Sequence: MAFLPKFDAGGLVTCVTTDAATGDVLMVAHMNDEALRRTVATGEAWYFSRSRNALWRKGESSGQTQRVIEMRTDCDQDAVWLRVEQTGAACHTGRRSCFYRRVERTEADGGARLVFVDADRLFDPDAVYRK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVRC_PSESG
Sequence: MGNVCFRPSRSHVSQEFSQSEFSTASPVRTSERPSDASLDAGLESSSACHRSGLRGPAKHSMLSLDEIGLVGAARWPDDAPGLNISNKSNTQENKRYCESLYQAARIAGGSIASGRVTSFDGLWRNATKWRLSRILSGDASKIDFATVRMPNTRFVTSLRRPYHSVIERVRNHSDANSEIYEGEYLGGIETKVYRQHGTISSTTIPMTIVSAVADDDDIHERLKSLPKNERRHLKDLMAASHPNMITHTDAVYLPMIKDHLESLYLQAIDPSLEQHEALELIARIHWWAASAAPDRRGSAAKAEFAARSIAFAHGIELPPFEHGAVPDIEAMLRSEEQFVEDYPNLFERPPQ
What are the official names of this protein?
Avirulence protein C.
What is the protein family that this protein belongs to?
To avirulence B protein of the same strain.
Protein: RRP41_PYRHO
Sequence: MMEKPEGLKLIDENGRRIDGRKKYELRPIKMKVGVLKNANGSAYIEWGRNKIIAAVYGPRELHSKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTSIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLTKEEFIEAVRLAIKGAKAVYQKQREALKEKYLKIAQEVEESE
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCA_RAT
Sequence: MTAAVVAAAATATMVSGSSGLAAARLLSRTFLLQQNGIRHGSYTASRKNIYIDKNTKVICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGKKHLGLPVFNTVKEAKEKTGATASVIYVPPPFAAAAINEAIDAEIPLVVCITEGIPQQDMVRVKHKLTRQGKTRLIGPNCPGIINPGECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCIGIGGDPFNGTNFIDCLDVFLKDPATEGIVLIGEIGGHAEENAAEFLKEHNSGPKAKPVVSFIAGITAPPGRRMGHAGAIIAGGKGGAKEKISALQSAGVIVSMSPAQLGTCMYKEFEKRKML
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
What are the official names of this protein?
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARAA_ECOLU
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSINTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MAOX_MOUSE
Sequence: MEPRAPRRRHTHQRGYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTENEELLKDPLYIGLRHRRVRGPEYDAFLDEFMEAASSKYGMNCLIQFEDFANRNAFRLLNKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLVVMAMEKEGLSKENARKKIWLVDSKGLIVKGRASLTEEKEVFAHEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTAEVISQQVSDKHLQEGRLYPPLNTIRGVSLKIAVKIVQDAYKEKMATVYPEPQNKEEFVSSQMYSTNYDQILPDCYPWPAEVQKIQTKVNQ
What is the function of this protein?
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate.
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_SERP5
Sequence: MFYPEQFDVIIIGGGHAGTEAAMAAARMGRQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDALGGLMATAIDHAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQPVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLENYSGGRAGDPPSISLSQRLRELPLRVNRLKTGTPPRIDARSIDFSVLAPQHGDTPIPVFSFMGNAGQHPEQMACYITYTNEKTHDVIRNNLDRSPMYAGIIEGIGPRYCPSIEDKVMRFADRNAHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMEGMQNARIIRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAGRYANEDEGWSPRRDQAYLGVLVDDLSTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEKGRELGLVDDARWARFSEKLEHIEQERQRLRDIWMHPHAENVEQVNALLKAPLSREANGEELLRRPEMDYTQLTSVAAFAPPLADTQAAEQVEIQVKYEGYIARQQEEIEKQQRNENTVLPLDLDYQQVSGLSNEVIAKLNDHKPNSIGQASRISGITPAAISILLIWLKKQGLLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGA_PROMH
Sequence: MKERSTELVDGFRHSVPYINAHRGKTFVIMLGGEAIAHENFPSIINDIGLLHSLGIRLVVVYGARPQIDVALEEQKISPLYHKHTRITDSKTLEVVKQSAGTLQLDITARLSMSLSNTPLQGAHINVVSGNFVIAQPLGVDDGVDYCHSGKIRRIDEEAIHRQLDNHAIVLIGPVAVSVTGESFNLTSEEVATQLAIKLKAQKLIGFCSSQGVVDASGQIVSELLPNQAEERIQALQTTGDYHSGTVRFLRGAVTACRRGVERSHLLSYQADGAIVQELFSRDGIGTQIVMESAEKVRRANINDIGGILELIRPLEQQGILVRRSREQLEMEIDQFTIIERDNLTIACAALYPYQSEKIGEMACVAVHPDYRSSCRGEVLLQRISTQAKQMGLDKLFVLTTRSIHWFQEKGFTPAEIDKLPIEKQALYNYQRRSKILILDLHKE
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLIA5_BOTMO
Sequence: MRLILLSSLLLLGIFLADGDEVDPDGKVLNSLIYGVMHLQREFANLKGAFLTVHRARSFGSGSERLYVTNKEIKNFEALRQICEQAEGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGTCVKADTHGSWHSASCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor clone 05, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: RPOB_MOOTA
Sequence: MAYPVKVGARERWTFAKIKETLELPNLIEIQRNSYQWFIDTGLRELFHDISPIQDFTGNLILQFVDYSLGEPKYSEDECKERDMTYAAPLRVKVRLINRETGEVKEQEVFMGDFPLMTDKGTFIINGAERVIVSQLVRSPGAYYAEGIDASGTKVYGATVIPNRGAWLEFETDNTESIYVRIDRTRKIPVTILLRALGYNTNARILELFDYDGRIQNTLEKDNTESEEEALVEIYKRLRPGEPPTVDSARNLLESLFFDPRRYDLGNVGRYKLHKKFNHGILTREVDGREEYIRTLTKEDIIYTIKYLLRLMDGEVKPDDIDHLGNRRLRSVGELLQNQFRIGLARMERVVRERMTIQDVDVITPQVLINIRPVVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVHTSHYGRMCPIETPEGPNIGLIGSLSTYARINEFGFIETPYRRVDKEKGIVTNQVDYLTADEEDKYFIAQANAPLDEEGHFLEKRVNARHGGEILVVPASQVDYMDVSPKQMVSVATALIPFLEHDDANRALMGANMQRQAVPLLRTEAPIVGTGMEWRAARDSGTVVLARNNGVVERVTAREIVIRTDNGHLETYRLQKFVRSNQGTCINQKPIVRKGERVSAGQTIADGPSTDQGELALGRNILVAFMTWEGYNYEDAILISEKLVKDDIFTSIHIEEYECDARDTKLGPEEITRDIPNVSEDVLKDLDERGIIRIGAEVRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIVVDVKVFSRENGDELAPGVNELVRVYIAQKRKISVGDKMAGRHGNKGVISRILPEEDMPFLPDGTPIEIVLNPLGVPSRMNLGQILETHLGRAARALGITVATPVFDGATEEEIKEAFRKAGLPEDGKTILYDGRTGEPFDRPITVGYMYMLKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLGLDVKVLSEENEEIEIKEDDDDVSESAQELGLDVHGQPNTAPESEGGNEEDKEAEADEDFDPADLDPSELELDADLNDDLVVPDEAYGDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: FTSK_HALH5
Sequence: MAKRKKKKKVAWQSQLTFELVGLGILVIAVVALAQLGTVGETLVRLFRFFLGEWYAVLSIALLVAALYIMVKREKPPLWSRRIGGLYLMLLSALLFSHVGLFGQLQGNEGFSDQSVIRNTWNLFWLDMYGEVQHSDLGGGMIGAIAYAASHFLFADGGTLFLCFILFMAGLILLTGHSITDLFGKAIRRTYLWVVDFIKGTWNEWKQFRKESKEKLEQDRKLLKERKEKKAAKRSRNEDPAQEENDQPLEIVDFSQRVSHEAKNDATVKQQVKPAKQEDQVSKEAPEEDKLASQGQEGEEMPTVSLATAVTPNDDYQLPTIELLKLPNNPNQSMEKRLLHKNAEKLRKTLESFGVKAHVSKVHLGPAVTKYEVNPHVGVKVSRIVNLADDLALALAAKDIRIEAPIPGKSAIGIEVPNQEVAIVTLREVLDSPQAKADRNVLSVGLGRDISGEPVFAPLNKMPHLLVAGATGSGKSVCINGIITSILLKAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTEPKKASQALKKVVAEMERRYDLFSHSGTRNIEGYNEMITRQNEKEDAKQPTLPYIVVIVDELADLMMVASGDVEDSIARLAQMARAAGIHMILATQRPSVDVITGVIKANIPSRIAFGVSSQTDSRTILDTGGAEKLLGRGDMLYLPMGATKPTRVQGAFLSDEEVETIVEFVVAQQKAQYAEEMTPTEETKVTEKVDDELYDDAVNLVIEMNSASVSMLQRRFRIGYTRAARLIDEMEARGIVGPYEGSKPREVLVQAQDDEASSH
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
Protein: G3P_PHANO
Sequence: MVVKVGINGFGRIGRIVFRNAIEHNDVEIVAVNDPFIEPHYAAYMLKYDSQHGQFKGDIKVEGNDLTINGKTIRFYTEKDPANIPWSETGAYYVVESTGVFTTTDKAKAHLKGGAKKVVISAPSADAPMFVMGVNNETYTKDIEVLSNASCTTNCLAPLAKVIHDKFTIIEGLMTTVHSYTATQKVVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPDLNGKLTGMSMRVPTSNVSVVDLTVRLEKGATYDEIKEAVKAAADGPLNGILGYTEDEIVSTDLNGDTRSSIFDAKAGISLNKNFVKLVSWYDNEWGYSRRVLDLLVYIAKVDGNA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_BRUA1
Sequence: MSELTALTIAEARDKLKAKAITATELTDAYLSAIDAANDAINAYVAVTHDQARSMAKASDERIAKGEAGALEGIPLGVKDLFATKGVHTQACSHILDGFKPEYESTVTANLWADGAVMLGKLNMDEVAMGSSNETSYYGPVKNPWRAKGSNADLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRVSRWGTVAFASSLDQAGPIARDVRDAAILMKSMASLDLKDTTSVDLPVPDYEAALGRSVKGMKIGIPREYRVDGMPGEIEELWQKGIQYLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIADMYEQTRAAGFGKEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKKDFEDVFAKGVDAILTPATPSAAFGLADEVLANDPVKMYLNDIFTVTVNMAGLPGIAVPAGLNGQGLPLGLQLIGRPFEEETLFQAAHVIEQAAGRFTPAKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SYI_CUPMC
Sequence: MSDDKRAKPEKSKYPVNLLDTPFPMRGDLPKREPQWVKQWQDKQLYKKIRAARHGAKKFVLHDGPPYANGDIHIGHAVNKVLKDMIIKARGLTGLDAVYVPGWDCHGMPIEIQIEKQFGKGLPVQEVQSKARAYATEQIARQRKDFERLGVLGDWENPYLTMNFSNEADELRALGKIMERGYVFRGLKPVNWCFDCGSALAEAEVEYKDKVDLSIDVGFPFAETDKIAHAFHVPLAQLEGKPGWIVIWTTTPWTIPSNQALNMHPEVEYALVDTPRGFLILAKDRVEEQLKTYALEGTIVATARGDALTEVRFHHPLAKMDAGYVRTSPVYLGDYVTTDTGTGIVHSAPAYGVEDFQSCKAHGMPDSDIISPVMGDGVYASTLPLFGGLSIWDANPKIVEVLRESGNLFNSHKYEHSYMHCWRHKTPIIYRATSQWFAGMDVDPVDNGPTLRETALAGIEATEFYPAWGKQRLHNMIANRPDWTLSRQRQWGVPMAFFVHKETGALHPRTPELLEEVAKLVEKHGIEAWQTLDPKDLLGDEAAQYEKNRDTLDVWFDSGTTHWTVIRGSHRDELYDPAADLPDGRLADLYLEGSDQHRGWFHSSLLTASMLYGKPPYKALLTHGFTVDGEGRKMSKSVGNTVSPQDISNKMGAEIIRLWVASTDYSGELSISDEILKRVVEGYRRIRNTLRFLLANLTDYDHAKHALPASEWLEIDRYAVALTDRLQKEVLSHYQAYEFHPVVAKLQTFCSEDLGGFYLDVLKDRLYTTAADSKARRGAQNALYHITQAMLHWMAPFLTFTAEEAWQIFAHGTEHKDTIFTSTYYAIPSVDDGDTLLQKWHEIRTVRAEVTRQLEAVRVEGDIGSSLQAEVTIAAGGPVLAALQSLEDDLRFVLLTSAAKVTPAPEGGDLLVTVTPSQHAKCERCWHYRADVGHNPEHPTICGRCDSNLFGAGEHRSHA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1139_DROME
Sequence: MNDDIKTVTVYPTTLELTTPTKSANGSNDDYDPHQHRELKNPTTNFQTFAHFLKASVGTGVLAMPSAFAHAGYVNGTLLTLIIGSLALYCLHILIKCMYILCKRQRVPYVSFSQAMNLGLKQGPPWLRCLAPIAVPFVDGFLAFYHFGICCVYVVFIAESIKQLVDEYLVVWDVRIHMCIIIVPLLLIYSIKNLKLLAPFSSAANLLLLVGFGIILYYIFEELPPLSERDPFVAAGKLPTFFGTVLFALEAVGVILAIEENMATPKSFVGPCGILNSGMSIVLGLYVLLGFFGYWKYGNESEGSITLNIPQSEIPAQVVKVFFAITTWISYALQGYVTAHILWDKYLAKRFKETRQTFYELIFRAIIVLLTFGCAVAIPDLSVFLSLVGSFCLSILGLIFPVLLQICVQYTEGYGPFRIKLIINLLLLCFGIFGGVVGTYVSILDIIAVYK
What is the function of this protein?
Amino acid transporter which has pH-dependent electrogenic transport activity for alanine, glycine and proline (PubMed:15843412).  Plays a role in positive regulation of growth by directly or indirectly modulating the effects of the TOR signaling pathway (PubMed:15843412, PubMed:22574197).
What are the official names of this protein?
Proton-coupled amino acid transporter-like protein CG1139.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BPT_BURCJ
Sequence: MTHPTELPLSPLSALQFYATAPYPCSYLDGRIARSQVATPSHLINSDIYTELVKAGFRRSGVFTYRPYCDGCRACVPVRVPVGEFAPTRTQRRMWKRHRALVATVSPLHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFRDLDAPGGEPGKLRMVSMIDILGDGLSSVYTFFEPDDRHTSYGTYNILWQIEQAKSLGLPYVYLGYWIRESPKMAYKANFHPLEGLIDGRWKTLDPERVDLPPVDAALARAPLPGGHSGSG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_DEHLB
Sequence: MALKFTTAEGQAITPITVPVMREIDRLAVQETGPNLYQMMENAGRNLAELTLTLLGESRNGSRVLVLAGTGGNGGGGLCAGRHLANHGLAVDYTLGDRDGLSEVTGRQLSLLELAGGREVDPVSPETGEADIVLDALIGYSLLGAPSGRSAELIRWLNAGNSRIISLDVPSGVDADSGLTPGEYVRPQTTLTLAWPKTGLLPRLTGELWLGDLGIPPAVYTRAGLKNFRSPFIAGYLVRLTASEQ
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: AROK_HALSA
Sequence: MDGRAVAPAAGTVLNALATGVGAAFALDIDTEASVSVTPSESGVSGEIAGHPEADTALVERCVSRVIDRYGDGQGGHVRTESEVPLAAGLKSSSAAANATVLATLDALGVADEVDRVDAARLGVQAARDAGVTVTGAFDDAAASMLGGVAMTDNREDDLLFRDAVEWHAAVWTPPERAYSADADVARCERVSGLAEHVAALAAAGDYGTAMTVNGLAFCAALDFPTAPAVTALPHAAGVSLSGTGPSYVAVGDEDGIEEVSTRWHENPGTVRETTTQLAGARTT
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.