PharMolix/UniProtQA huggingface dataset:
Protein: WALK_STAA9
Sequence: MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue in the dimerization domain and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of WalR.  In turn, WalR binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_LISPE
Sequence: MTNIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALFLILTLLALTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIVGQLASILYFFLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GATA_BRUO2
Sequence: MSELTALTIAEARDKLKAKAITATELTDAYLSAIDAANDAINAYVAVTHDQARSMAKASDERIAKGEAGALEGIPLGVKDLFATKGVHTQACSHILDGFKPEYESTVTANLWADGAVMLGKLNMDEFAMGSSNETSYYGPVKNPWRAKGSNADLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRVSRWGTVAFASSLDQAGPIARDVRDAAILMKSMASLDLKDTTSVDLPVPDYEAALGRSVKGMKIGIPREYRVDGMPGEIEELWQKGIQYLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIADMYEQTRAAGFGKEAKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKKDFEDVFAKGVDAILTPATPSAAFGLADEVLANDPVKMYLNDIFTVTVNMAGLPGIAVPAGLNGQGLPLGLQLIGRPFEEETLFQAAHVIEQAAGRFTPAKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: 3CP2_STRSQ
Sequence: CLGVGSCNDFAGCGYAIVCFW
What is the function of this protein?
Inhibits chicken myosin light chain kinase with an IC(50) of 8 M.  Does not inhibit bovine cAMP-dependent protein kinase or rat protein kinase C.  Antibacterial activity against the Gram-positive bacteria B. subtilis, E. faecium and S. aureus.  No antibacterial activity against the Gram-negative bacteria E. coli, K. pneumoniae, P. aeruginosa, P. vulgaris, S. sonnei and S. typhosa.  No antifungal activity against C. albicans.
What are the official names of this protein?
Tricyclic peptide MS-271, Class I lasso peptide.
Protein: FLGH_BUCBP
Sequence: MVITLLNLNKKHYLLILFFILLNGCSIDKNIILNKKQKQHKIFNLPITHTSKETHNFNYQDNKQSNNNYLEPLFEDYKPRNVGDILTIILQENTSASNSVSNNSIHNGNSNFDIDIGNARAFDDPNGILNKIELNSSIKNNFLGKGSSSANNTFVGLITVIVDRILPNGNLEVSGSKNITINDGIEKICFYGIVNPHTISKNNSVLSTKVANTNITYISSGPINIGSKINWLQRLFVSLFTLSK
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: SCAF_BPMV4
Sequence: MERKFLTDLGLNPDQVNSIMAQYGKDMQKYEGLEAERDALKKTSSELSNKIEDLKANSANIEDLTKQIEKLKLDNENATKQLSAQKLDFAVTSTIKDFGAKNAKAVKALLNHDDIRFDSKGNLTGLEEQLKSLKDSDSYLFAEDKPAGKPIQAFLRGTGSWRQGCQPASEDCTKIERINK
What is the function of this protein?
Scaffolding protein involved in the icosahedric procapsid assembly.  Coassembles with the capsid proteins to form the procapsid, in which the scaffolding protein is found within the external shell of icosahedrally arranged capsid protein subunits.  In a subsequent step the scaffolding protein molecules are released from the procapsid.
What are the official names of this protein?
Capsid assembly scaffolding protein, Head morphogenesis protein, Minor structural protein Gp20, ORF2 protein, Scaffold protein.
What is the protein family that this protein belongs to?
Belongs to the SPP1-like scaffolding protein family.
Protein: OTU1_RAT
Sequence: MFGGAKGGHFGVPPAGCSGAVSQAAAGTKAGPAGGRPADTMWRLRCKAKGGTHVLQGLSNRTRLRELQGQIAAITGIAPGSQRILVGYPPECLDLSDRDITLGDLPIQSGDMLIVEEDQTRPKASPAFSKHGAPSYVRETLPVLTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDLYSEAILGKTNEEYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRKRQFTDVNRFTLRCMLCQKGLTGQAEARDHARETGHTNFGEV
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins.  May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore.  Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel.  Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.  Cleaves both polyubiquitin and di-ubiquitin.  May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.  May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation.
What are the official names of this protein?
Ubiquitin thioesterase OTU1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: XYLB_BACOV
Sequence: MKTEKRYLVPGDYMADPAVHVFDGKLYIYPSHDWESGIAENDNGDHFNMKDYHVYSMDDVMNGEIKDHGVVLSTEDIPWAGRQLWDCDVVCKDGKYYMYFPLKDQNDIFRIGVAVSDKPYGPFIPEANPMKGSYSIDPAVWDDGDGNYYIYFGGLWGGQLQRYRNNKALESAILPEGEEEAIPSRVARLSEDMMEFAEEPRAVVILDEDGKPLTAGDTERRFFEASWMHKYNGKYYFSYSTGDTHLLCYATGDNPYGPFTYQGVILTPVVGWTTHHAIVEFKGKWYLFHHDCVPSEGKTWLRSLKVCELQYDADGRIITIEGKDE
What are the official names of this protein?
Xylosidase/arabinosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
Protein: RRP12_MOUSE
Sequence: MGRSGKLPSGVSAKLKRWKKGHSSDSNPATCRHRQAARSRFFSRPSGKSDLTVDAVKLHNELQSGTLSLGKSQAPETTMDQDPEVAFTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAAHKEICAVLAAVTEVIRSQGGKETETEYFAALMTTMEAVESPESLAAVAYLLNLVLKRVPSPVLMKKFSDTSKAFMDIMSAQASSGSTSALRWVLSCLAILLRKQDLEAWGYPITLQVYHGLLSFTVHAKPKIRKAAQHGVCSVLKGSDFMFGEKAPAHHPAAVSTAKFCIQEIEKSGGSKEATTTLHMLTLLKDMLPCFPEGLVKSCSETLLRVMTLNHVLVTACAMQAFHNLFHAKPSPSTLSAELNAQIVTALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQRDLGLGHLARFFGTAVTCLLSPHSQVAAAATQTLKEILKECVAPHIADIGSVTSSASGPPQYITKMFRAVEEGLTYKFHAAWSSVLQLLGVFFEACGKQAHPVMKKCLQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVRETRLGFFTTYFLPLATTLKRKAMDLAQAGSTVESKIYDTLQWQIWTLLPGFCTRPTDVAASFKGLARTLGTAINERPDLRVTVCQALRTLITKGCEAEADRAEVSRFAKNFLPILFNLYGQPVAAGEAAAPRRAVLETIKTYLTITEAQLVNSFLEKATEKVLDPASSDFTRLSVLDLVVALAPYSDEAAISKLYSTIRPYLESKVHGVQKKAYRVLEEVCASSQGPAARFVQSHLDDLKKTLLDSLRTTSSPAKRPRLKCLIHIVKTLSAEHEEFIAALIPEVILCTKEVSVGARKSAFTLLVEMGHAFLRFGSNQEDALQRYLVLIYPGLLGAVTTVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVVVMDVVHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFIKFTRKFGFELVKGLLPAEYHKVLINIRKAETRAKKHRALSQAAVEEEEEEEEEEEPVQSKGDSIEEILADSEDEDEEEERGRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAHRVLATQPGPGRGKKRDHGFKLSADGRLIIREEEDGNKVEEEDGTKGEDEDMTDAMEDASVRSKKKLKRQREDEEDELEIPPRYQAGGSGIHRPVAKKAAPGAEYKAKKAKGDVKKKGRLDPYAYVPLNRSKLNRRKKVKLQGQFKGLVKATQRGSQAGHKLRRKDRRRP
What are the official names of this protein?
RRP12-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP12 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus membrane; Single-pass membrane protein.
Protein: RIBB_MARSD
Sequence: MNQNLLSQYGTPVERVEKGLQALREGRGILVTDNESRENEGDLIFSAEKLSDEQMAMMIRECSGIVCLCLTDEKTEQLGLPMMVESNSSRYQTGFTVTIEAAEGVTTGVSAADRVTTVKAAIADGAKPADLHRPGHVFPLRAREGGVLEREGHTEATVDMMTLAGLNPCGVLCELTNPDGTMARLPEIVEFGQKHDMPVLTVDDIINYRIQLAKKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: TXS4A_CUPSA
Sequence: FLAKKVGKQLASHLAKKQLE
What are the official names of this protein?
Short cationic peptide-4a, SCP-4a, Short cationic peptide-4c, SCP-4c, Truncated variant of Cupiennin 4 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 04 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GAL1_SALEP
Sequence: MNLKEKTRALFAEIFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRTVRVIAADYDNQVDEFSLDAPIVTHDSQQWSNYVRGVVKHLQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGAKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVASELDPVVAKRVRHVLSENARTVEAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVDIVKATIGDQGGVRMTGGGFGGCVVALIPEDLVPAVQQAVAQQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBP1_HYSCR
Sequence: EVVRSNNFDPSKLSGKWYSILLASDRKE
What is the function of this protein?
This soluble protein may play a specific role in odor discrimination and perception.
What are the official names of this protein?
Odorant-binding protein 1, Odorant-binding protein I, OBP I, Olfactory mucosa pyrazine-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TSAD_PSEF5
Sequence: MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRAYGGVVPELASRDHVKRMLPLIRQVLAEADCVPTEIDAIAYTAGPGLVGALLVGASCAQALAFAWGIPALGVHHMEGHLLAPMLEEQPPQFPFVALLVSGGHTQLVRVDGIGQYELLGETLDDAAGEAFDKTAKMIGLNYPGGPEIARLATQGVAGRFVFPRPMTDRPGLDFSFSGLKTFALNTWQQCVSAGDDGEQTRCDISLAFQQAVVETLTIKCKRALKQTGLKRLVIAGGVSANKALRASLEKMLAEMKGNVFYARPEFCTDNGAMIAFAGCQRLQAGQQESLAISVQARWPMEQLSAL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRMD8_HUMAN
Sequence: MDGTEGSAGQPGPAERSHRSSVSSVGARAADVLVYLADDTVVPLAVENLPSLSAHELHRAVREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDEPFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQLGPYQPGRPAACDLREKLDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQEVSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLEGVHVIDSREKHVLLGLRFQELSWDHTSPEEEEPILWLEFDGDSEGTPVNKLLKIYSKQAELMSSLIEYCIELSQAAEPAGPQDSATGSPSDPSSSLAPVQRPKLRRQGSVVSSRIQHLSTIDYVEDGKGIRRVKPKRTTSFFSRQLSLGQGSYTVVQPGDSLEQG
What is the function of this protein?
Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway.  By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (PubMed:29897333, PubMed:29897336).  Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (PubMed:19572019).
What are the official names of this protein?
FERM domain-containing protein 8, Band4.1 inhibitor LRP interactor, Bili, iRhom tail-associated protein, iTAP.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane.
Protein: RL33_FLAPJ
Sequence: MAKKGNRIQVILECTEHKASGVAGTSRYITTKNKKNTPDRLEIKKFNPVLKRVTVHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS6_ANAPZ
Sequence: MPFYEFAFIAQQGLTQYELEGLSKGLTALLVKMGAELVKYEYWGLLDFVYSIAKNNKGHYCMMYIRAEPAAMDEFKRKVKLNEDVLRFLCLKVDKVPEGRSAMMGSDQD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: EZRA_BACCN
Sequence: MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNMTGQTEELFGKWREDWDEIVATILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEADNRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLAHRHMYGAAEQKIEELLDVESDKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQGHDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQLEKEVHAKYYVEQKTIRVYDDLEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMHILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVLHAEYKEMLQAMRKEEFEAREKLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSELEEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAALEQAASVLEQLEPGVVQKIAEFVDNEQTS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: SELA_PROMH
Sequence: MTHDTRSLYSQLSSIDSLLHQADIQTLVDGYGQTFIVEHLRKLQEEARIIIRQNNQLPQWHDNWAEELKNRIALQRKAAIKPVFNLTGTVLHTNLGRALMAESAIEAVSQVMRSPATLEYSLDGASRGHRDRAIADLLCELTGAEDACIVNNNAAAVLLMLATVAPDKEVVVSRGELVEIGGAFRIPDVMCQAGCRLKEVGTTNRTHLKDYRNAINENTGLLMKVHTSNYSIQGFTAEVEGTQLAALGKEMNLPTAIDLGSGSMTNLAALGLPSEPMPQDYLQQGIDLVTFSGDKLLGGPQAGIILGKKAWIEAIQHHPLKRALRVDKMTLAALDATLRLYQQPEKMIKDIPTLRLLTRTQTEIHDMAQRLLPHFQAYYGDNYHITISSCASQIGSGSLPIESLPSAALTFAAKDGKGSQLDALAAHWRNLEKPIIGRITDGRLWLDLRCLEDENALIQALSL
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_LEVBA
Sequence: MDYKQIVTAALSDALAGQLTRDEIASKLERPKTSDKGDMAFPTFTLAKLLHQAPQQIAQDLAEKLDKTSFEKVEVVGPYLNFFFDKGAYSAETLQTVLTAGADYGQNDDGQGGNVPIDMSSPNIAKPMSMGHLRSTVIGNSIAEILTKNGYHPIKDNHLGDWGTQFGKLITAYKLWGNEADVKADPINKLVEYYVRFHKEDVDKPELDDTAREWFRKLENGDEEAHELWQWFRDASLQEFNDVYEKLGVTFDTFNGEAFYNDKLEEVVQILKDKNLLVESQGAQVVDLSKYNLNPALILKSDGASLYITRDIATALYRDRTYHPAKNLYVVGSEQTYYFKQLKAVLQEMGVPSADDLEHIPFGLITVDGKKLSTRSGRIILLAKVLDDSVKLAAEEINEKNPDLANKDEVAQQVGVGAIVFGDLKNERTNNIDFVLADQLKFEGETGPYVQYSHARAESILRKAGKVTITTDGNQISDPEAWDTIKTLADFPAMVKMACDEFEPSVIAKYAIRLAKTFNKYYAHSKILTEDAELPARLALVKAVSTVLKESLRLLGVQAPDEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_LISIN
Sequence: MTKTLTKKLANKDHASVVTYIMGGDGGLDNLEEQLLFLEKSGVSAIEIGIPFSDPVADGPVIQLAGLRALKERVSLEAILTKLATSKVQIPLIIMSYINPIFHLGIPKFIEMVQKTPVKGLIIPDLPYEHRTLITPELKGTDIALIPLVSLTSPKERLEEIANQAEGFIYAVTVNGTTGVRNEFNTHIDTHLAYLKSISPVPVLAGFGVSSIEHVEKFARVCDGVIIGSKVVQMLHDGETRELGTFLQNAAEVQIEN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: H3_TIGCA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RNH_FRATF
Sequence: MEIFKKKNRVIAYTDGACKGNPGIGGWGAILSYNGVDKEIYGSEKDTTNNRMELMAAIKTLQALKRKCDITIYTDSKYLQNGINEWLANWKANGWKTAAKKEVKNKDLWQELDSLTNKHNVTWGWVKGHSGNAGNEKADELANKAIAELIGK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_MYXXA
Sequence: MIREQRSSRGGSRDQRTNRRIRAREVRVVGSDGSQLGVMPLEAALDRARTEGLDLVEISPMASPPVCKIMDYGKFKYEEKKKASEAKRAQVTVLLKEVKLRPKTEEHDYEFKVRNTRRFIEDGNKAKVVIQFRGREITHREQGTAILDDVAKDLKDVAVVEQMPRMEGRLMFMILAPTPKVAQKARELVRQAATAAKRPPPPGAPGAGKSAAGASSGAEEKAEETAEEKKEAQAAPAAAEAQSPTAS
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYK1_PHOLE
Sequence: ASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGESAKGKYPIEAVTIMAQICARTDDVVKPELGSRLDSPRLRITEAVCKGAVDTAEKLNAPLIIVATEAGKSARSVRKYFPTARILAVTTNTKTAAQLCLSKGVTPVVVDSIESTDAFYLRGKELALETGLGAKGDIVVMVSGALVASGTTNTASVHVL
What are the official names of this protein?
Pyruvate kinase I, PK-1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: MED18_KLULA
Sequence: MVQQLALFSAIEDESYPLSVETLTILSSNRPRLFANFNKIYKPNPSLQIEKVNAKNQLVEQTRVKLSTAVPLSKLGNGAELNYHFMEKLSNDDIESFNVKSYIQDIDSNNKTNWAFQISDIPAAGNNRKLSSQTIHESVIQSSSGSVSSFIDELGYVNDFQYINVGVKFQFLSGVVMEIYKVWQVVQKDQEVSMKLITKDGFMIKAMYNVNKSTDIESLNNGSQLLLKLKTDLRDYIELDIPDRKCMDTRLNHLD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAND_CLOB1
Sequence: MTITMLKSKIHRATVTEANLNYVGSITIDKYLMDKANILEYEKVQIVDIDNGNRFETYVIAGEKHSDVICLNGAAARMVQKGDKIIIMSYCSLTIDEANKFNPTVLFVDNKNNIEKLTNYEKHGEII
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETD_MOUSE
Sequence: MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK
What are the official names of this protein?
Embryonic testis differentiation protein.
Protein: EFTU_CLOBL
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAQKGGASATKYDEIDKAPEEKERGITINTSHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLASRVGVQYIVVFLNKADQVDDPELIELVEMEVRELLNEYGFPGDDTPIVVGSALEVLENQDNAEKTKCIDELMEAIDSYIPTPERATDQPFLMPVEDVFTITGRGTVATGRVERGVLHTGDEVELIGMKQEVSKTVCTGIEMFRKILDEAMAGDNIGALLRGIQRDEIQRGQVLAKPGSVTPHKKFVGQVYVLKKEEGGRHTPFFNGYRPQFYFRTTDVTGSINLPEGVEMVMPGDHIDMAVELITPVAMHENLRFAIREGGRTVGSGVVTTISE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.