PharMolix/UniProtQA huggingface dataset:
Protein: PROA_ANAD2
Sequence: MRKEKSLGLAAEMRKLAEASREAARALSHADPRRKDAALRAAAEAIGRREKRILSENARDVAAARAAGQNAAYLDRLRLDPKRLAGIGAALHEIAGLRDPVGEVTASWRRPNGLEIRKVRIPLGVVLMVYEARPNVTVDAAALCLKSGNAAILRPGSDALRSSLALAAAFAEGLEKAGLPAASAQVVPTPDREATYELLALDDLIDLAIPRGGPSLIRAVAARSRVPVLKHYQGVCHLYLDASAPPQQAVDLALNGKVQRPGVCNATECLLVHRGAAGKLLPPVGRALADAGVELRCDPTALTILKRAGVAAVPARPDDFGKEFLDKILAVRVVADLDGALDHIARYGSLHTEAIVTRDLASARRFQREVDASAVMVNASTRFNDGGELGLGAEIGISTTKLHAFGPMGLAELTTQKFLVEGEGHVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMA_DESVH
Sequence: MYGSFTQLGDSFSIDLRVVDALGVKPAKPFFIQKQGIINILPAVDELVDRVAGEFTSGNAIADVKVRGTKVLDPDVVLMRLSTRKGDPIDPAAINKEIKRIWDLGYFSDVQASVEQGGDGTVLVYTVTEKPRIDNIVIEGSDKVGHDDILAAMSSKTGSVLNDKLLAQDLQKVTELYRKEGFYLAHVTHRVEARQGAASATLVLNVEEGNKLYIKKVKIEGLKELSESEVKDILALSERGMFSWFTGTGVLKDELLERDSAAITAYCLNHGYVDALVSAPKVDYEEDGIIVSFAVKEGPRYKLGKIGFDGELIDTDERLLKVVKLDDHKKDNQYFALDVMQTDDKLLSDYYADYGYAFAEINSRTQKSAEEHVIDVTYVIRKRQKVYINRVLVEGNQKTRDNVVLREMRIADGDMFEGAKLRRSNERLNRTRYFSQVDTELVPTQKEDEVDLKVKVKEQNTGALIGGVGYSTFYQFGVSGTIMERNLFGKGYYASLQAFFSGKRNSFIASFTNPRVNDGDLSFGNDAYISREYFDDFSKNTIGDTIRFALPVGEYSTVGWGYRLDRYELYDIDDDAAKIIKEREGENISSVAHVRFTRDTTDSKEKPTKGTIFKTFNEFGGGPIGGDDDFIKPVVEFQAYHQLAPNHVLHGRTRGGAVLENGQGDVPVFERFYIGGIDSIRGYNSRDISPRDPESGDRIGGDRMAFVNLEYIWVFKPDLGLALVPFFDMGINYDSSAEFNWDDELKKSVGLEMRWRSPMGDLRFAYGFPLDEGRDGEQHSGRFEFSMGQFF
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: METK_BURPS
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQGAGDQGLMFGYACDETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGKPHSIDTVVLSTQHAPEIDLPALREAVIEEVIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDETITKLVREHFDLRPKGIIQMLDLLRPIYEKTAAYGHFGREEPEFSWEAADKALALAEAAGVEPAVQVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STRT1
Sequence: MKVKLITVGKLKEKYLKDGIAEYIKRLGRFTKFESIELTDEKTPDNASEAENKAILDKEGQRILAKVGDRDYVIALAIEGKQFPSEQFAKELEQATLRGYSDITFIIGGSLGLSPKVKKRANQLMSFGLLTFPHQLMRLILVEQIYRAFMIQQGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECG_PSEPO
Sequence: MGRFLLVTLSLLVVAFSLNGANSCCCPQDWLPRNGFCYKVFNHLKNWNDAEMYCRKFKPGCHLASLHSNADAVEFSEYITDYLTGQGHVWIGLRDTKKKYIWEWTDRSRTDFLPWRKDQPDHFNNEEFCVETVNFTGYLQWNDDSCTALRPFLCQCKY
What is the function of this protein?
Galactose-binding lectin that binds to and agglutinates erythrocytes in a calcium-dependent manner.
What are the official names of this protein?
C-type lectin galactose-binding isoform, CTL, Venom C-type lectin galactose binding isoform.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCAD_ECOBW
Sequence: MSTYTQPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CU037_HUMAN
Sequence: MERAQCLRKGILSFERSLEQRSLILSPRLEYSGAITAHCSLDLLDSTNPPASAFWVVETTDTEDEREKKREITE
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01549.
Protein: VATI_HALSA
Sequence: MLRPEQMSKVSVAGSTHVLTPVIEAVHDAELVHLSDYDGGIDGFDNGDPMTGADEAAEKLVTVRSLKSLLDVSEGDAGPTRIVTDDALDTELESIRVEATDLDDRRSELTDDLRAVIERIDAAEPFADLGIDLDLLSGYDSLQVAVGTGDQSAIDAALAASDRISAFETFTGQDTIGVFAYPAADDDAALDDALVGVPFTRLDVPDADGSPEQYVSELRERRDTIQAEIEDVDDELAAFRDEHAGFLLAAEERLAIDVQKSEAPLQFASTSHAFVAEGWLPTSEYDAFTDAIESAVGDHVLVEELERADYKPTGHDQHVPADDGADAATDGGTTASFDETDSPPVIQDNPGPVSSFESLTEVINRPQYTEIDPTVVLFLTFPAFYGFMIGDLGYGVLYALLGFWLSRSFDSEMISKLGGVAMWAGGFTALFGVLYGEVFGLHLVTEYLWHGALGLADAPLKKGLHVSAFAELWLAASLVFGIAHLAIGYVFGFVNESRSHGLKDAALESGGQLLLMAGVGVWLFSTHMQSGGGPRPELLYSVVALPPIVGKAGLAAAVVGLVLVTLGEGAAGFLESPTYALVNTVSYTRIAAVLLAKAGMAYVVNLLVFGAYETHLEHPETIDYMFGLFSTTIEHETHFMLFSGEAHGEVLFPGLMHMGAAGILIGVLVLLVGHALVLALGVTSAGLQALRLEYVEFFNKFYEGGGEKYNPFGYTRNYTTED
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS24A_YEAST
Sequence: MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S24-A, RP50, Small ribosomal subunit protein eS24-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: PUR9_ALIF1
Sequence: MNNARPIRRALISVSDKTGIVEFAQALAERGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDIMEQHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNAHDYDRVIAEMDANEKSLTLETRFDLAIAAFEHTASYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFEKKQDMRYGENSHQAAAFYVEANPEEASVSTARQIQGKALSYNNIADTDAALECVKEFDEPACVIVKHANPCGVALGKDILEAYDRAFKTDPTSAFGGIIAFNRELDAATATAITERQFVEVIIAPSVSTEAVEIVAAKKNLRLLECGEWTTKTTGFDVKRVNGGLLVQDRDQGMVSEDDLQVVSKRQPTAEELKDALFCWKVAKYVKSNAIVYSKGDMTIGVGAGQMSRVYSAKIAGIKAADEGLQVEGCVMASDAFFPFRDGIDAAAEAGIKCVIQPGGSMRDNEVIEAADEHGMAMIFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SPEE_HAMD5
Sequence: MSQKQLWYEKLHSSFGQYFSIKEVLYRDKTDHQDLIIFDTEEFGRVMALNHVVQTTERDEFIYHEMMTHVPLLAHGDAKKVLIIGGGDGGILREVCRHAGVKEIIMVEIDQDVVNLCQEYFPHHHAGAYDDPRFQLKIDDGAHFVEQTNHRFDLIISDSTDPIGPGEHLFKSSFYQACRRILNAGGLFVAQNGVCFLQQTEVINTYQRLMPYFSDVSFYQAAIPTYYGGIMTFAWASENANLRRIGLNDLESRFADSGLKSCRYYNPFVHFASFALPQYLIEALAKKAPK
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_OEDCA
Sequence: MTRVKRGIIARKRRQKILNMNKGFRGAASVLFRTANQRYMKSLRSAYENRHNKKRNFRKLWISRLNSAVRLNGLNYSQFVYMLKKSGIILNRKILSQLSICDPQIFHELYSYIASKNLI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S23A2_RAT
Sequence: MMGVGKNTSKSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV
What is the function of this protein?
Sodium/ascorbate cotransporter (PubMed:10331392).  Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate (By similarity).
What are the official names of this protein?
Solute carrier family 23 member 2, Na(+)/L-ascorbic acid transporter 2, Sodium-dependent vitamin C transporter 2.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1446_STRA3
Sequence: MANVYDLANELERAVRALPEYQAVLTAKAAIENDADAQVLWQDFLAAQSKVQEMMQSGQMPSQEEQDEMSKLGEKIESNDLLKVYFDHQQRLSVYMSDIEKIVFAPMQDLM
What are the official names of this protein?
UPF0342 protein gbs1446.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: RNP3_NATPD
Sequence: MYEGVHAHPDGNATVARFAETAASRGYDGIVVRNHGDAQTDYDADAVAAEYGVEVVSGIEIRTDDTAQASGLVGNYRSKRDIVCVHGGELNRFAVEEPKVDVLAHPMRDGDVNHVLAKAAAENGVHFEFNFGRVLRADGGKRVQAIQGLRKLRELVDQYDAPYVVSADPESHLELRSSRDLAAVGETVGFDREAITDGLAAWADIVERNRRRRSAAVVEPGVRIERADGETDDSRE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECOSE
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SERC_RALSO
Sequence: MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESIMAQAFADLRELLAVPDNYEILFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVKSQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYVHLCTNETIVGVEYQETPDIGQAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPSAFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASGFYRNDIHPSCRSRMNVPFFLNDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPLEGVEALVDFMREFERTAA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_STRE4
Sequence: MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINTRHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAIVMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKDITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIENNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSENEWHT
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHF14_HUMAN
Sequence: MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQECDSSSSKEDENEAERKNISQELNMEQKNPKK
What is the function of this protein?
Histone-binding protein (PubMed:23688586).  Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trimethylated at 'Lys-27' (H3K27me3) (By similarity).  Represses PDGFRA expression, thus playing a role in regulation of mesenchymal cell proliferation (By similarity).  Suppresses the expression of CDKN1A/p21 by reducing the level of trimethylation of histone H3 'Lys-4', leading to enhanced proliferation of germinal center B cells (By similarity).
What are the official names of this protein?
PHD finger protein 14.
Protein: UNG_SINSX
Sequence: EFASAYMADLKQFLVAQKNEGRQIFPRGPEYFRALDLTPLDKVRVVILGQDPYHGDGQAHGLCFSVRPGVRTPPSLVNIYKELNTDLGIPPARHGFLESWARQGVLLLNSVLTVRARERASHQGHGWEKFTDAIIRAVNEAEHPVVFMLWGSYAQKKAAFVDRSRHLVLRAPHPSPLSAHSGFLGCRHFSQANAFLESKGFDPIDWRLPENPAADIN
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_CLOAB
Sequence: MKKMQEPIEDPLSKLTQYSGKTFVIKYGGSIMKNKKAEEAFIKDVKYLRKLGINIVIVHGGGPEISRWLELSGIESRFVDGLRVTDEKVIEIVQMVLSGKINKKLSLQFNIDGVNAVGLSGVDNKLIEATKKYVYKGNETIDIGYVGKVTKVNSEFIKELLKGGQVPVIAPIGCDNKGNVYNINADYAAAFISSALDAEKLIILTDVEGVYRNINDPQSIIHEIDIKDVNYYIKEEIIKGGMIPKVQCCASAIENGTKNVQLIDGRNDHCLINDILNYRGTIISYRSGVKCQKAI
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_STUS1
Sequence: MKQYLDLMRHVREHGTFKSDRTGTGTYSVFGYQMRFDLAEGFPLVTTKKCHLKSIIHELLWFLQGDTNIKYLKENGVRIWDEWADENGELGPVYGYQWRSWPAPNGESIDQIANLLAMIKKNPDSRRLIVSAWNPALVEQMALPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVCDLEPGEFIWSGGDCHLYANHLEQADLQLTREPLPLPTMKLNPEVKDLFAFRFEDFELVGYEAHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
Protein: Y1775_BACHK
Sequence: MRDNTIGSLIWLRLIRFTNQSNQMSNEFLKRFDLTTAQFDVLLQIRTYQPLTQMELAEKVTVTQGGISRMLTRLEKEGYIVRKQDWKTKTISLTEQGEAALERALPEQLAFQSSFFDDVLNEEEQKILYELMTKVHKHSEKKELPQE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator BT9727_1775.
Protein: ZPR1_DICDI
Sequence: MSEEIINKKLENTKIEEKEEEFKNISHENEVTEIESYCVNCEAENGITRILLTKVPFFKEIMVFAFHCPECGFRSSEVRSGGSYELKGCHIELNVTKELDLNRQIVKMEKATISIPSLDFEIPPSNNGSLNTIEGIIKEAITNLTNASEIHTESKEELLGFVSKLSNLLMVDEPFKIIVDDPSGNSFIENPNAPKADTNLKVTNYTRTAEQNASLGLGINEEQQKQQQEDSKKNERVTTTSVSIPSGDLADREVYSLPNQCSYCGVMGECKMVLTDIPYFKSILLMAFSCDECGYKTNEIKPGGAISEKGKTITLRVESVEDLSRDILKSDTANVIIPELEIEVTHGSLGGKFTTVEGLITIIKEELEKNPFFRGDSSDPANRARYQEITSQLDSFIAGKKPFTIELDDPISNSYIQNLFAPDDDPQLKIVEYERTYEQNDELGLNAMNTENYLNNQEENDNEAENEKSEEKESDSK
What are the official names of this protein?
Zinc finger protein ZPR1 homolog, Zinc finger protein 259 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZPR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTPE_MYCTO
Sequence: MTRSASATAGLTDAEVAQRVAEGKSNDIPERVTRTVGQIVRANVFTRINAILGVLLLIVLATGSLINGMFGLLIIANSVIGMVQEIRAKQTLDKLAIIGQAKPLVRRQSGTRTRSTNEVVLDDIIELGPGDQVVVDGEVVEEENLEIDESLLTGEADPIAKDAGDTVMSGSFVVSGAGAYRATKVGSEAYAAKLAAEASKFTLVKSELRNGINRILQFITYLLVPAGLLTIYTQLFTTHVGWRESVLRMVGALVPMVPEGLVLMTSIAFAVGVVRLGQRQCLVQELPAIEGLARVDVVCADKTGTLTESGMRVCEVEELDGAGRQESVADVLAALAAADARPNASMQAIAEAFHSPPGWVVAANAPFKSATKWSGVSFRDHGNWVIGAPDVLLDPASVAARQAERIGAQGLRVLLLAAGSVAVDHAQAPGQVTPVALVVLEQKVRPDARETLDYFAVQNVSVKVISGDNAVSVGAVADRLGLHGEAMDARALPTGREELADTLDSYTSFGRVRPDQKRAIVHALQSHGHTVAMTGDGVNDVLALKDADIGVAMGSGSPASRAVAQIVLLNNRFATLPHVVGEGRRVIGNIERVANLFLTKTVYSVLLALLVGIECLIAIPLRRDPLLFPFQPIHVTIAAWFTIGIPAFILSLAPNNERAYPGFVRRVMTSAVPFGLVIGVATFVTYLAAYQGRYASWQEQEQASTAALITLLMTALWVLAVIARPYQWWRLALVLPSGLAYVVIFSLPLAREKFLLDASNLATTSIALAVGVVGAATIEAMWWIRSRMLGVKPRVWR
What is the function of this protein?
P-type ATPase involved in specific uptake of calcium.
What are the official names of this protein?
Calcium-transporting ATPase CtpE.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: END3_MYCTO
Sequence: MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: LGT_RICFE
Sequence: MTFPNINPIIFSIGPLAVSWYSLSYVVGILLGWFYANKIIEKFKPQITKKNLEDFITYAVIGIIVGGRLGFVLLYNPSRYFSNPIDILKTYEGGMSFHGGALGVIIAAYLFCRKYKINFLSLTDIIAPVVPIGLFLGRIANFINGELYGRITNSSFGMIFPNSDLMPRHPSQLYEAFFEGLVLFCILAYATFKHKTLKKYGLNSGIFLIFYALFRIAIEIFREPDIQIGFILDSLTMGQILSVPMLLLGSYLICQSNPK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.