PharMolix/UniProtQA huggingface dataset:
Protein: PSBM_GLOC7
Sequence: MQVNDLGFIATILFVLVPTVFLLILYIQTRKETEG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MTAP_SCHPO
Sequence: MNKQAEPILLGVIGGSGFYDLPGFDIVESVNPITPWGYPASPISIARTTSGFLIAFLARHGVGHIYTPTEVPSRANIAALKSLGVLAIVSFSAVGSLREDIPPEDFVLPTQIIDRTLCARPNTFFESGCVAHVSFGDPFDQDLYEILSSCGSNLKNGSKLHTKRKGDDLTVVCMEGPAFSTRAESNLYRSWGASIINMSVIPEAKLAREAEIAYQMVCMATDYDCWRMNEEPVTVETVMEHISNNKDNAKIFLLEAVKKLEAPLLQGFLGRNLRESVQNGIQTNHKHRNPDAIRRLQFLFPNLTIPH
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA_HELPH
Sequence: MKIAVLLSGGVDSSYSAYSLKEQGHELVGIYLKLHASEKKHDLYIKNAQKACEFLGIPLEVLDFQKDFKSAVYDEFISAYEEGQTPNPCALCNPLMKFGLALDHALKLGCEKIATGHYARVKEIDKVSYIQEAVDKTKDQSYFLYALEHEVIAKLVFPLGDLLKKDIKPLALNAMPFLGTLETYKESQEICFVEKSYIDTLKKHVEVEKEGVVKNLQGEVIGTHKGYMQYTIGKRKGFNIKGALEPHFVVGIDAKKNELIVGKKEDLATHSLKAKNKSLTKDFKDGEYFIKARYRSVPAKAFVSLRDEVIEVEFEEPFYGVAKGQALVVYKDDILLGGGVIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_DESVV
Sequence: MDLLKELESLVPELERGLGQASSLQELEEQRIAFLGRKGRLAQVMAHLPELAPAERPRVGQAANTVKQALTELFEQRKVVLEQAKEAAALSRFDPSLPGRMPWRGSLHPVTLVMEEICSVFGALGYDIVTGPEVENDYHNFEALNMPPEHPARDMQDTLYITESILMRTHTSPLQVRTMKSLRPPVAAIAPGKVYRRDSDITHTPMFHQIEGFMVDHNVSMAELRGTLTSFLRTVFGGDTRVRFRPSFFPFTEPSAEVDISCCICGGKGHVGNEPCRVCKTTGWVEILGCGMIDPEVFKSVGYDPEVYTGFAFGLGVERVAMLKYGIGDLRMFFENDVRFLSQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_CAMFF
Sequence: MRDEVFKRPIKKQFEFDESVVSVFDDMVSRSVPYYCDVQALISLILSKNLSPNAKVFDLGCSTATTLLEIFKLRSDLSLNGVDSSEAMIKTARNRSLAYLANLNLYVSDILDFDFSGSDAVILNYTLQFIRPIKREEFIKKIYSNLKSGGIFIFSEKLVYEDKKLTLDMIEIYENYKHSQGYSKFEIAQKRQALENILIPYSENENKELCLNAGFKSVETIFKWANFATFIAFK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: RL5_SYNE7
Sequence: MSLKTKYRDIIVPKLMKEFGYTNIHQVPKVVKVTINRGLGEGAQNAKALESSLAEIAKIAGQKPVVTRAKKAIAGFKIRAGMPVGLMVTLRGDRRDAFLERLINLSLPRIRDFRGISPRSFDGRGNYTLGLREQLIFPEITYDSIDQIRGMDITIVTSANSDEEGRALLRELGMPFREN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YTDC2_PONAB
Sequence: MSRPSSVSPRQPAPGGGGGGGPSPCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPGSQRQRTVLNVTDEYDLLDDGGDAVFSQLTEKDVNCLEPWLVKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPVADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFKLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPSPALHPPQKYKDRGILHPKRGTEDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPVRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPQVGEQLLQLWERLPLGEKNTTD
What is the function of this protein?
3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells.  Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability.  Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs.  Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease.  Required for both spermatogenesis and oogenesis.
What are the official names of this protein?
3'-5' RNA helicase YTHDC2, YTH domain-containing protein C2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: CCMH_ORYSJ
Sequence: MATEEDVKQRQIIESRARNISHNVRCTECGSQSIEDSQADIAILLRKLIRDEIKSGKSDKEIYKKLQADYGETILYTPKFDLQTAAIWLSPVIVGGVAAGVWAYQKHRQRTNVHIMALNLVRGVPLTPREKETMLDVLTPPPPANKWWWPGK
What is the function of this protein?
Plays a role in mitochondrial cytochrome c maturation.  Probable component of a heme lyase complex involved in the reduction of apocytochrome c.
What are the official names of this protein?
Cytochrome c-type biogenesis CcmH-like mitochondrial protein, OsCCMH.
What is the protein family that this protein belongs to?
Belongs to the CcmH/CycL/Ccl2/NrfF family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LIRP1_ARATH
Sequence: MQGALFIKPTILLPLPSSVSSPKLTFLLPHATKASRLSSLRSNNSSSSSSLTSDPNTVDYNSSILSVFPAEACEVISGYACSADIYPEVKLDTKPVSRPVASEPVDREYEEYNSPKTVFREEACDDLGGEFCEPDFQKDAN
What is the function of this protein?
Thylakoid-determinant subunit of high molecular weight LFNRs-containing protein complexes.
What are the official names of this protein?
Light-regulated protein 1, chloroplastic, Protein CCR-LIKE, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Plastid, chloroplast envelope. Plastid, chloroplast stroma.
Protein: ABF2_CAEEL
Sequence: MFVRSLFLALLLATIVAADIDFSTCARMDVPILKKAAQGLCITSCSMQNCGTGSCKKRSGRPTCVCYRCANGGGDIPLGALIKRG
What is the function of this protein?
Exhibits antimicrobial activity against the Gram-positive bacteria B. subtilis IFO 3134, K. varians MAFF 118076 and S. aureus ATCC 6538P, the Gram-negative bacteria A. tumefaciens MAFF 1001, B. bacteriovorus MAFF 106101 and K. pneumoniae MAFF 519002, and the yeasts C. krusei MAFF 114085, K. thermotolerans MAFF 113848 and T. delbrueckii MAFF 113811.
What are the official names of this protein?
Antibacterial factor-related peptide 2.
What are the subcellular locations of this protein?
Secreted.
Protein: THIM_LACLM
Sequence: MSILSKIQRTQPLILNLANFVTPQRVADVISFIGASPLMTSEIAELESLVEISDAVVVNIGTISESTYPLFLEACRLANQKAKPLILDPVAVNIPFRASIVKRLSQEVKFNIIRGNSAEIAWFADKKSLNKGIDALESNIDNEHARLAAKKTGTVIIETGKVDIISNGHEEMYVDTDSPLFKINVGCGDMLTAVVGTFAAVSDDLFTAAYEATKFFGEAGMIATKQVQNLPGNFVNSLLDTLYQTTHEIK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: APHA_RAHSY
Sequence: MRKTPLALSAVFLLLSLNQSAFAKEPAPAPLWPGVNVAQLAQQSPVHWVSVAQIENSLNGRPPIAVGFDIDDTVLFSSPGFYRGQVEFSPGKQDYLKNPKFWEKMNNGWDDFSMPKEVAKSLIAMHLKRGDSIYFVTGRSETKTETVTKTLQNDFQIPQDKVNAVIFAGDKAGQNTKTQWLKDKQIKVFYGDSDNDITAAQSVSARGIRVLRASNSSYKPLPQAGAFGEEVIVNSEY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters.  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS4_AZOC5
Sequence: MILFPAIDLKDGLAVRLEQGDMDRATVFNRDPASQAGEFEALGFRYLHLVDLNGAFAGHPVNAAAVDRILETVSIPVQLGGGIRDMKTVDGWLEKGVTRVILGTAAVRDPDFVKAAAKAHPGRVVVGLDARDGNVAVQGWAETSNLPAVDIARRFEDAGVSAIIYTDIARDGLLKGLNMDATIALADAVSIPVIASGGLASLADVEALLEPRAKKLAGAITGRALYDGRLDPGAALALVAGRS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPC2_HUMAN
Sequence: MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADMARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQELKAKAHK
What is the function of this protein?
Mediates the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Mitochondrial pyruvate carrier 2, Brain protein 44.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
Protein: PNCB_VIBPA
Sequence: MTTTLFSSRIIQSALDFDVYKVNMMSAVAALYPDAMVSYKFIVRSEEDLSELLPEVKAEVLKLQDVRFTEDEIAYMKRVAPYLKPEFVEALRHFRFNPQSDVSFHNKTMSDGSSQLRITINGLWKETILYETIIMSIVSEVRSRQRWSDIPFEQFQTVLEDKVRYLKAELERRNITNFKFADMSTRRRFSFQAQRTMLEYLSKELPQCLTGTSNYHLARELDLTPIGTVAHEWFMGHQALVNVRDSQKIALQRWQKMFNGALGIALTDTIGIDAFLKDFDEELSHAYVGVRHDSGCPFTWGEKMIAHYESLGIDPMTKTLVFTDGLNFEQALDICEHFQGRVQVSFGIGTSLANDMGNYVNDQGEAYQPLSIVIKMVTCNGSPVAKISDEPEKAMCEDIFFLMNLKRRFEQPLDLNECRKLIDRLESEGQNYLIDA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: SYI_VIBA3
Sequence: MSDYKDTLNLPETGFPMRGNLANREPEMLKRWYKEDLYGEIRKAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDIIIKSKTLSGFDAPYIPGWDCHGLPIELMVEKKKGKPGQKISAAEFREECRKYAAGQVEGQKESFKRLGIMGEWDKPYRTMDFGTEANIIRSLGKIADKGHLLKGFKPVHWCTDCGSALAEAEVEYKDKVSPSIDVKFTAADEAALLEKFTLAEGHAGQGEISIVIWTTTPWTLPANRAVCLRDDLEYVLIQVEANGDQPAQRIVVASELAKDVMDRAGIEHFHNLGFATGADLELSQFNHPFYNFTVPAVLGDHVTTDSGTGVVHTAPGHGQEDFVVGKKYNLEIANPVGSNGVYLPDTELFAGQHVFKANDSVLEVLKEKGALLHHHAYEHSYPHCWRHKTPIIFRATPQWFISMDQAGLRAKALESTKSVEWMPEWGQSRIEGMIEGRPEWCISRQRTWGVPIALFVHKETSELHPDSPALIEKVAKLVEEKGIQAWWDVDAAELMGAEDADKYEKVLDTLDVWFDSGVTHFSVVDSREEYNFPNEERTHSADLYLEGSDQHRGWFQSSLISSIAMKDEAPYKQVLTHGFVVDGNGRKMSKSIGNVVAPKDVTNKLGADILRLWVASTDYTNEVAVSDEILKRSADAYRRIRNTARFFLANLNGFNPETDLVPAEEMVALDRWAVGRAQAAQEEIVKAYGEYNTHGVTQRLMQFCSIEMGSFYLDVIKDRQYTAKQGSHAQRSCQTALYYIVEALVRWMAPIMSFTADEIWNEMPGERDTFVFTGEWFEGLFGLADDEELSNEFWTEIQSVRGAVNKLLEDARKEKTIGGALQAEVTLYADDALAAKINKLEDELRFVLITSAAVVKPLSDKSDTAQATDVEGLYVEVAATEAEKCDRCWHHTPDVGTIEGHEKICGRCVSNIDGEGEVRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VU25_HHV6U
Sequence: MGLSSSKDIDLLVNFIENRQGATLALPWPEDYRLTLHSVENIPEISREDVQNWAKTYMCCGGELVVVGVIHKAKTRTCRGPIVLQGARGHIYVYNGFFDRSLYHVASSFHDLFSNGLRFFYPIYETCDYALDSTVALDMIAHSKSFSELLHYRNERKNAFFTLKTYPYKTFVRFCNLSMTEFSSRHLIQWRRKLQTSLLDVVFIVQHNFFGDWRELVVVFDGHGMLFCVDREESLLFIARNMSDFLKIGCLRYNENRRLHTQWFTQDTDYIKQVDEMFSRDVLCPLREHCQRSRRERGLLKICTSLVRGVNCIERG
What are the official names of this protein?
Protein U25.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: XGEA_ASPCL
Sequence: MKFNLALALSLTVATAEAATELCKQWDSIIEGNFIVYNNLWGQGNADDGGHQCTTVKSISGDTVVWSTEWAWSGGPGQVKSYANAALQFTPTTLSSVSSIDSTWKWRDSYTGSDIVANVAYDMFLSSSATGSEEYEIMVWLAALGGAGPISSTGSPIATPTINGVQWDLYLGPNGAMQVYSFVAPSSTENFAGDMKGFIDYLTSEQGLSKDLYLLDVQAGTEPFSGSDAVLTVSEYSVNLA
What is the function of this protein?
Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues.  Specific for xyloglucan and does not hydrolyze other cell wall components (By similarity).
What are the official names of this protein?
Probable xyloglucan-specific endo-beta-1,4-glucanase A, Xyloglucanase A, Xyloglucanendohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 12 (cellulase H) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIOB_SCHPO
Sequence: MTCNHENPHFLFKIDSYSKTFLLSCYCVSIYRLEECSGRFKPSSYSLHLLKSLSIIICENPSQTFNIGLNQPK
What are the official names of this protein?
Uncharacterized protein P27G11.11c.
Protein: PURZ_BPSHA
Sequence: MKKATVICDMQFGSTGKGLIAGFLAERDQPDVVVTAWSANAGHTYINREGRKWVHCMLANGIVSPKLKAVLIGGGSQMSIPTLISEIMGSLDILQGKSILIHENACIIQQRHVEEEAGPMTKIGSTKKGCGAAMMEKIRRNPESKIVAKDFIDDGLEIPDFKLDGTVGFKDISRHFEELGVCIKVVSNEVYLAVLHKAERVQVEGAQGFSLGLHNGFYPYVTSRECTPAQICSDCNVPISMVDKVVGTMRTYPIRVANRFDDEGKMVGWSGPCYSDQTELTWEQMGVTPEKTTVTKLTRRIFSFSRMQTRQAMLVCMPDEIFLNFANYCASEDELASIIEVISNEGGDVSYIGWGDSAAHIETTLEGDWSDDTNPLFNQYNKSSNIA
What is the function of this protein?
Involved in the synthesis of the atypical nucleotide dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate) (PubMed:33926954).  Catalyzes the condensation of aspartate with deoxyguanylate into dSMP (N6-succino-2-amino-2'-deoxyadenylate), which undergoes defumarylation and phosphorylation respectively by host PurB and guanylate/nucleoside diphosphate kinases to give dZTP (PubMed:33926954).  dZTP is integrated into the viral genome instead of adenine by the viral DNA polymerase.  This Z-base probably completely replaces adenosine and forms a triple bond to the opposite T-base (PubMed:33926954).  The resulting non-standard viral DNA is called Z-genome (PubMed:33926954).  The chemically modified DNA is probably harder for the host bacteria to digest with nucleases or restriction enzymes (Probable).
What are the official names of this protein?
N6-succino-2-amino-2'-deoxyadenylate synthase, 2-amino-2'-deoxyadenylo-succinate synthase, PurZ.
What is the protein family that this protein belongs to?
Belongs to the Caudovirales PurZ family.
Protein: RBFA_STAAS
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB1_STRCO
Sequence: MNETMICAVGNVATTPVFRDLANGPSVRFRLAVTARYWDREKNAWTDGHTNFFTVWANRQLATNASGSLAVGDPVVVQGRLKVRTDVREGQSRTSADIDAVAIGHDLARGTAAFRRTARTEASTSPPRPEPNWEVPAGGTPGEPVPEQRPDPVPVG
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: PGK_ACHLI
Sequence: MAKKTIRDIELKNKSVLMRVDFNVPLNKDGSISDDTRITAALPTIEYAIEKGAKLILFSHLGRIKTAEDKATNSLKPVAARLSELIGRPVVFIPETRGEALEAAVKNLKSGDVLMFENTRFEDLDGNKESKNNPELGKYWASLGDVFVNDAFGTAHRAHASNVGIANNMEVSVAGLLLEKEINFIGGALENPERPFVAILGGAKVSDKIEVIKNLLKVADKVLIGGGMAFTFLKAQGFEVGKSLVELDKLDLAKELLELSKGKIELGFDVVTGKAFDKDTETNVRSFDAIPADEMGLDIGPKTVARFKEIIASAKTVVWNGPQGVFEMEKFANGTLEVTKALADLHGKAITIVGGGDSAAAVAKFGLEDKFSHISTGGGASLEYLEGKVLPGVELVDVI
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_METM5
Sequence: MITDRVSDYLEKIEKSDVNAFIDVNSEKVLKEAEELEKNDDLKNKPLYGKIVAVKSNINVKGYKISCASKTLEKYVGTYDATVVKKLRSQGALIVGMTNMDEFAGGSSGETSCYGPTKNPAALDRIPGGSSSGSAAAVAADLCDMAIGSDTGGSIRNPASHCGIVGFKPSYGVVSRQGLCDLAMSFDQIGPLTKNAEDALVLTNAIKGIDRSDSTSLETPKFEKKDISNYKVGVVKEFMDVTDEKIRNEIEKGIEVFKDMGCKIVDLSYKYIDLALPTYYLINYVEFFSATRKYDGRRYGEFIEEACGEEVLRRILIGKHISEQEFSGKYYKKALQARKSMKKEMLGLFNSADLIVGPTVPKLPHKLGEDLSPMEMYAYDVLTVPTNICGICSGVVRCGNISGVPVGLQIQGAPLEDEKVLSAMIEFEKNY
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS4_BURP6
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRISGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGETLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKAITVNGIVANIPSQQVKAGDVVAIREKAKKQARIVEALSLAEQGGMPSWVAVDAKKFEGTFKQVPERADIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TBP_META3
Sequence: MSSEIKIVNVVVSTKIGDDIDLEYVADVLDNSEYEPEQFPGLVCRLSDPKVALLIFRSGKLNCTGAKSKEDAVIAINKVMEYLREAGLDLIDTPEVKVQNMVATAELGMEPNLDDLSTLERTEYEPEQFPGLVYRMESPKVVLLVFGSGKVVITGLKNKEDAYIALEKIKNTVKELEEEYF
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: DNLJ_BEII9
Sequence: MTVQKPIESLSPAQAKREHRRLGEQITEHDRLYYQEDAPRVSDAEYDALRRRYEALETAFPELVSAESLTKKIGAAPAEKFAKIIHKVPMLSLANIFSDEEVGEFVARVRRFLGLGADAPLAISAEPKIDGLSCSLRYEGGYLVQAATRGDGYEGEDVTANVRTIQEIPHQLQGHAPEILEVRGEVYMTHADFAALNERQEAAGKTIFANPRNSAAGSLRQLDPKVTAGRPLHFFAYAWGEASEEPADTQMGMVTAFKAFGLPVNPLMQLCHSAEDLIAHYHDIEARRALLDYDIDGVVYKVNSIALQKRLGFVSRAPRWATAHKFPAEKAVTLLRDIEIQVGRTGALTPVARLEPITVGGVVVSNATLHNEDEIARKDIRIGDMVMIQRAGDVIPQILGPILDKRPQDAQPYEFPQVCPVCGSAAIREIDPKTGTADVVRRCTGGLVCAAQVVERLKHFASRNAFDIEGLGDKQIEQFYHDGLIHTPVDIFTLQERDARSLKKLKDREGYGETSVRNLFQAIEARRHIPVNRFIYALGIRHVGETNARRAARAFGTFDALRAVASRAEEGSEERSELTNVEGFGPVVAEAIFDFFHEQHNQDVLDGLLEQVTPEPMEAVAKESPVAGKTVVFTGALEHMTREEAKAQAERLGAKVAGSVSKKTDLVVAGPGAGSKLAKAAELNIETISEEDWLKLVGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PGK_STRT2
Sequence: MAKLTVKDVELKGKKVLVRVDFNVPVKDGVITNDNRITAALPTIKYILEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVKFIPGVTRGAELEAAVNSLEDGQVLLVENTRFEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVENPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFFKAQGIEIGNSLVEEDKLDVAKALLEKSNGKLILPVDSKEANAFADYTEVKYTEGEAVDPGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGYADKFSWISTGGGASMELLEGKELPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKD1B_HUMAN
Sequence: MDPAGRARGQGATAGGLLLRAAAAAKGLREDLWGAAALPWRSLSRIPKREGLGEEDTAVAGHELLLPNERSFQNAAKSNNLDLMEKLFEKKVNINVVNNMNRTALHFAVGRNHLSAVDFLLKHKARVDVADKHGLTVIHLAAWSGSLEVMLMLVKAGADQRAKNQDGMSALHFATQSNHVRIVEYLIQDLHLKDLNQPDEKGRKPFLLAAERGHVEMIEKLTFLNLHTSEKDKGGNTALHLAAKHGHSPAVQVLLAQWQDINEMNELNISSLQIATRNGHASLVNFLLSENVDLHQKVEPKESPLHLVVINNHITVVNSLLSAQHDIDILNQKQQTPLHVAADRGNVELVETLLKAGCDLKAVDKQGKTALAVASRSNHSLVVGMLIKAERYYAWREEHHESIRDPSTGFTLTFKQDHSLETRHIRTLLWDLAYHQLKANEWQRLARSWNFTDDQIRAIEEQWSGNESFREHGHRALLIWLHGTLMTQGDPAKQLYEELVHAGFPKLAEKTRHFKSKTDSNSKKCVVS
What are the official names of this protein?
Ankyrin repeat and death domain-containing protein 1B.