PharMolix/UniProtQA huggingface dataset:
Protein: LEPR_HUMAN
Sequence: MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQTCSTQTHKIMENKMCDLTV
What is the function of this protein?
Antagonizes Isoform A and isoform B-mediated LEP binding and endocytosis.
What are the official names of this protein?
Leptin receptor, LEP-R, HuB219, OB receptor, OB-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane. SUBCELLULAR LOCATION: [Isoform E]: Secreted.
Protein: YJJB_SALPK
Sequence: MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGALGHGSRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_ACHLA
Sequence: MITSIELRNFRNLENYKVLINRPLVIIQGLNGVGKTSILESIYFAATTKSHRSSVEKDMIQYDKPYASVKLIEDSKLHEIVLTPNGKRTTINKSEVRKISDYIGQLRVVMFAPEDLMLIKGSPSERRYFLDMELMQVSKTYLRNLNSYKKILKQRNALLKKNRNLTDYTFLNILGEQLYDVGIQIFDERQKFIEALNQKFKTIQTKYKDFEVEMLYEPNVTKENFLKHLKTKQKQDIMYETTTAGIHKDDFKLLYKGLNAKDSASQGTSRLIVIELKLALLEWIKEVTKTDAILLLDDVLSELDLERQNLFMSQLSKNHQVFITTALPINGHIDFQKIVLQEGETINAK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_UREPA
Sequence: MDKIKAKIDELKQKLDQWNYEYYVLDDPSVPDHVYDQTMRELIELENNYPQFKTNNSPSVKVGGFVSEKFNKVKHKRPMLSLSNAFNDDDLKKFDQDNQNASVDLKGYVVEPKIDGLSISIIYKNAKLHQAITRGDGINGEDVTSNILTIKDIPHYIDQKYKDYEIEVRGEVYMAFHDFYEMNDNLEESDKKFANPRNAAAGTLRSLDNSIVAERKLSAFMYYLVNAQELGIKTHYESIQFLRDNKFKVSDLIVKVDTINEVINQIDCYTKVRDKLSYMIDGIVIKINNLEVYDEIGYTSKFPKWAIAYKFPANVVSSQLLEIINDVGRTGKISYVAKIKPILLDGSMVEYATLHNFDFIKEKDIRINDEIKIYKAGDVIPYVDGVDLSKRLANSVPYEPIINCPSCQSVLVRENDEVDQRCLNIYGCKKINIEKIVYFVSRNCMNIEGMSDAIINKFYDANLIKNIADLYYLQKHKEFILTSDFKIKEKSFSNLINSINNSKKCSLEFLLTAFGIRHVGPNLAKKIAKQFKTMTALMHANFDELTNVDACGEKAALSLINWFNDEHNVSLVNQLQQVGVNMEYIDDFIYDDNINIIDEYKNKTFVITGSFSISRDEIKTILEKYYHAKVKNSVSKKTDYVLVGTEAGTKLEKAKLLGVKIIENEFWKKDNNF
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL13_ECO27
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y2326_MYCTU
Sequence: MCCAVCGPEPGRIGEVTPLGPCPAQHRGGPLRPSELAQASVMAALCAVTAIISVVVPFAAGLALLGTVPTGLLAYRYRLRVLAAATVAAGMIAFLIAGLGGFMGVVHSAYIGGLTGIVKRRGRGTPTVVVSSLIGGFVFGAAMVGMLAAMVRLRHLIFKVMTANVDGIAATLARMHMQGAAADVKRYFAEGLQYWPWVLLGYFNIGIMIVSLIGWWALSRLLERMRGIPDVHKLDPPPGDDVDALIGPVPVRLDKVRFRYPRAGQDALREVSLDVRAGEHLAIIGANGSGKTTLMLILAGRAPTSGTVDRPGTVGLGKLGGTAVVLQHPESQVLGTRVADDVVWGLPLGTTADVGRLLSEVGLEALAERDTGSLSGGELQRLALAAALAREPAMLIADEVTTMVDQQGRDALLAVLSGLTQRHRTALVHITHYDNEADSADRTLSLSDSPDNTDMVHTAAMPAPVIGVDQPQHAPALELVGVGHEYASGTPWAKTALRDINFVVEQGDGVLIHGGNGSGKSTLAWIMAGLTIPTTGACLLDGRPTHEQVGAVALSFQAARLQLMRSRVDLEVASAAGFSASEQDRVAAALTVVGLDPALGARRIDQLSGGQMRRVVLAGLLARAPRALILDEPLAGLDAASQRGLLRLLEDLRRARGLTVVVVSHDFAGMEELCPRTLHLRDGVLESAAASEAGGMS
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Rv2326c.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METN2_STAEQ
Sequence: MIKLNQIVKRYHTKDKDVLAVDHVDLNIESGSIFGVIGFSGAGKSTLIRMFNNLESPTSGEIIIDGDNISQLSKSQLRKKRQKVSMIFQHFNLLWSRSVLKNVTFPLEIAGVPSGLAKQKALELIELVGLKGRESAYPSELSGGQKQRVGIARALANDPDVLLCDEATSALDPQTTDEILDLLLKVREQQNLTIVLITHEMHVIRRICDEVAVMENGKVIEQGAVSKVFENPQHEVTKRFVKDDLNDDFEDSLEYLEPLDHDAYIVRLNFTGENTTEPIISYMTTTHNIDVNILEADIKNTKNGSFGFLVIHIPHISEEHFKQFKHNLHEQHVNVEVLKHG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ZN726_HUMAN
Sequence: MGLLTFRDVAIEFSLEEWQCLDTAQKNLYRNVMLENYRNLAFLGIAVSKPDLIICLEKEKEPWNMKRDEMVDEPPGICPHFAQDIWPEQGVEDSFQKVILRRFEKCGHENLQLRKGCKSVDECKVHKEGYNGLNQCFTTTQGKASQCGKYLKVFYKFINLNRYKIRHTRKKPFKCKNCVKSFCMFSHKTQHKSIYTTEKSYKCKECGKTFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHTGEKPYKCEECGKAFSQSSTLTIHKRIHTGEKPCKCEECGKAFSQPSALTIHKRMHIGEKPYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQFGHLTTHRIIHTGEKPYKCEECGKAFIWPSTLTKHKRIHTGEKPYKCEECGKAFHRSSNLTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECSKAFSRSSALTTHKRMHTGEKPYKCEECGKAFSQSSTLTAHKIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSNLSTHKIIHTGEKPYKCEECGKAFNRSSNLSTHKIIHTGEKPYKCDECGKSFIWSSTLFKHKRIHT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 726.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPR_HAEIG
Sequence: MYISRNLEQWNAFLQMLKIAFEENKAQEFLTLLLTADERDAVGLRLQIVSQLIDKNMPQREIQQNLNTSAATITRGSNMIKTMDPDFMQWMKQHLDLIEKN
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STAAC
Sequence: MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLC1_YEAST
Sequence: MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENGPVVCHGFLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTDKLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  Required for cell growth, osmoresistance and expression of GPD1.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1, Phosphoinositide phospholipase C, Phospholipase C-1, PLC-1.
Protein: HEP_DROME
Sequence: MSTIEFETIGSRLQSLEAKLQAQNESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPHYKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSNYVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTSPTLQSRSPEQQSDYGGNGNMVASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAGWFNTLAGAMKRQFATYVKTQLNSTATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLSAASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRYNRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRGSESVPGSPQHFRTRIHYTPEPQRRIYRTIDQ
What is the function of this protein?
Required for the epithelial cell sheet movement called dorsal closure (DC), which allows establishment of the dorsal epidermis.  Controls the expression in the dorsal epithelium edges of another dorsal closure gene, puckered (puc).  Phosphorylates and activates the MAP kinase bsk; bsk signal transduction pathway mediates an immune response and morphogenesis.
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase hemipterous, MAPKK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: FAR4_HOMAM
Sequence: TNRNFLRF
What is the function of this protein?
Can act as a modulator of exoskeletal and cardiac neuromuscular junctions.
What are the official names of this protein?
FMRFamide-like neuropeptide 4, FLI 4, F1.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_RICPR
Sequence: MSNLKQLRTRIKSVKSTQKITKAMQLVSASKMTKIKTQIANSNFYIEAINKMMSDICSMTSCELSIEEQKFFNTMPSKINLLIVMTSERGLCGMFNYSIIKQVKNDIKELTNKGEQIKLIIIGKKGYEALKRQYANYINSYFEFTKIHSENLILQVKEKIMCAVKNLEVSNCIIYFNKFKNAMTQIPTKQKILPIEKHQDYSVVANDYFEYEGKNLISNLINLYVHAKINYALLQNIVSEEGARMTAMENATNNANDLISKLVLKLNRSRQTIITTELIEIIAGAEAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TPCB_ASPFU
Sequence: MLALHQTQRDVPCSEVHDALGLQGARSIYFGRPTGRSILSDPIRPRPMPTVTVIIYSDIRFLLEFPSVFLCAYVLPVQRTVIMANEKRGGYRQINQALNICAWEGYLNEQHARLPTLEDVEQISPRVLRVLGQNEGKVRRADGYYTCSSRLIEGPQFTLQGTNTYIVGTGRHRLLIDTGQGIPEWASLISSTLAGSSIELSHVLLTHWHGDHTGGVPDLLRMYPDLSDSIYKHTPGKGQKPISDGQTFRVEGATVRAVHTPGHSHDHMCFILEEENAMFTGDNVLGHGSSAVEVLSTWMSSLRMMQSLRCAVGYPAHGAVIRDLPSKLDLELTQKARREDRVVETLKQMKTETQRNGARGKGSVTVQQLVTAMHGHDLDEQVRTMALEPFVDEVLRKLAQDDRVAFEVRGGQKKWFAIEYT
What is the function of this protein?
Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of trypacidin, a mycotoxin with antiprotozoal activity and that plays a role in the infection process (PubMed:26278536, PubMed:26242966).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) tpcC (PubMed:26242966).  The atrochrysone carboxyl ACP thioesterase tpcB then breaks the thioester bond and releases the atrochrysone carboxylic acid from tpcC (PubMed:26242966).  The decarboxylase tpcK converts atrochrysone carboxylic acid to atrochrysone which is further reduced into emodin anthrone (PubMed:26242966).  The next step is performed by the emodin anthrone oxygenase tpcL that catalyzes the oxidation of emodin anthrone to emodin (PubMed:26242966).  Emodin O-methyltransferase encoded by tpcA catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:26242966).  Ring cleavage of questin by questin oxidase tpcI leads to desmethylsulochrin via several intermediates including questin epoxide (By similarity).  Another methylation step catalyzed by tpcM leads to the formation of sulochrin which is further converted to monomethylsulfochrin by tpcH.  Finally, the tpcJ catalyzes the conversion of monomethylsulfochrin to trypacidin (PubMed:26242966).  Trypacidin is toxic for human pulmonary and bronchial epithelial cells by initiating the intracellular formation of nitric oxide (NO) and hydrogen peroxide (H(2)O(2)), thus triggering host necrotic cell death (PubMed:22319557).  The trypacidin pathway is also able to produce endocrocin via a distinct route from the endocrocin Enc pathway (PubMed:26242966).
What are the official names of this protein?
Atrochrysone carboxyl ACP thioesterase, ACTE, Trypacidin synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: TBP_PYRWO
Sequence: MVDMSKVKLRIENIVASVDLFAQLDLEKVLDLCPNSKYNPEEFPGIICHLDDPKVALLIFSSGKLVVTGAKSVQDIERAVAKLAQKLKSIGVKFKRAPQIDVQNMVFSGDIGREFNLDVVALTLPNCEYEPEQFPGVIYRVKEPKSVILLFSSGKIVCSGAKSEADAWEAVRKLLRELDKYGLLEEEEEEL
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: SYFB_NOCFA
Sequence: MRVAQSWLTEIIERTNAGWSVTPEELDAGFVRVGLEVEEVDRLERVGGDIERPLVVGRVAEITELTEFKKPIRFCKVDVGAPELQEIICGARNFAVGDLVVVVLPGGVLPGGFRITSRKTYGHVSNGMICSVAELGIGKDHSGILVLEPGTAEPGTDANELLGLDDTVIELNITPDRGYCFSVRGLARELACGFDLEYLDPAVRTLPEDAAEAWPITIEPASQCTRFAARRVTGIDPNAVSPWWLQRRLLLSGVRPISPAVDVTNYVMLELGQPLHAFDAAKLSGGLVVRTAKPGEKLRTLDDTERTLDAEDVVIADDSGAVSLAGIMGGASTEVGEGTTDVLLEAATWNPLLVYRTARRHKLVSEAGKRYERVVDPEINVAALDRAATLLAEIAGGTVEPVLSDVRVPTPAPEPIRMDIDLPDRVAGVAYPTGTAARRLAQIGCHVEVSVDEESGHGQLVVTPPSWRPDLAQPADLVEEVLRLEGLEQIPSVVPTAPAGRGLTPEQRRRRAVSRALAFAGGVEVPPPVFLPAGVFDTWGLDADDPRRTTTRVLNPLDVERAELATTLLPGLLEVAQRNISRGARDLTLYGIAQVVLPTGDTKPVAPLPVDRRPTDEQIAELLGSLPDQPVHVAAVLTGRREPRGPWGPGRQAEAADAFALVDAVADAAGVVIERRPAAYLPWHPGRCAELVVEGRVVGYAGELHPAVLERSGLPARTCALELDLDALPLRESRPVPVVSPFPAVLQDVSVSVSKSVAAAAVESALRSGGGELLEDIALFDVYEGAQAGEGRKSLTYALRFRAPDRTLTEDEASAARDAAVAAAADAVGAVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_SHEFN
Sequence: MPIITLPDGSKREFANPVSTLDVALDIGPGLAKACIAGRVNGELKDATDLITADSELAIITAKDEEGVEILRHSCAHLLGHAIKQMWPETKMAIGPVIDNGFYYDIDLDHKLTHEDIEALEKRMLALAKTNYDVVKKVVSWQEARDAFDGRGEEYKIAILDENISKDATPALYHHEEYIDMCRGPHVPNMRFCQNFKLMSVAGAYWRGNSDNKMLQRVYGTAWADKKALKTHLVRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSIFLELEKFIRQKLGQYTYQEVKGPLMMDRVLWERSGHWDKYAEAMFTTNSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHVFCTDDQVQEEVSACIQMVYDTYATFGFDNIVVKLSTRPEKRIGDDDMWDRAEDALKQALANNNIKYEILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPTRLGATYVAEDNSRQTPVMIHRAILGSLERFIGILIEEYAGKFPTWLAPMQVVVMNITDKQADYVEEIVKFFKEQGIRASFDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGIDLGKLKLEDFAAMIRQQISLRSLKLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_ALIF1
Sequence: METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLDTFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQIPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQPKAVIIDINCLKTLPEREFAAGMAEVIKYGIIVDREFFDWLDENMDKLYALDHDALIYAISRCCQIKADVVAKDEKESGMRALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQSDVERICSILEKAKLPLKAPKEMTVDAFMKHMMRDKKVLSGKLRLVLPTSIGSSEVVTGVSESVLAEVIEQCKA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_CHLL3
Sequence: MAQFKRTLVTTALPYANGPVHLGHLAGVYLPADIYVRHKRLKGEEVLHIGGSDEHGVPITITAEKEGISPRDVVDRYHRMNLEAFLKCGISFDCYGRTSSELHHETAQEFFLELERKGIFNRRTEKLFYDAEGGRFLSDRYVSGTCPICGSTEASGDQCEQCGTHLSPMELINPKSKISNATPELRDTLHWYFPLGRYQAELERFVNSHEDDWRSNVLNYTRTWLKGGLNDRAITRDLNWGIKVPLGEAEAVGKVLYVWFDAVLGYISFTRQWAEEQGDRDLWRHWWQNPETRLVQFIGKDNVVFHTLMLPAILMAWNEGREDGIYNLADNVPASEFMNFEGRKFSKSRNYAVYLGEFLQKFPADTLRYSIAMNYPENKDTDFSWTDFQNRTNGELADTLGNFIKRSIDFTNSRFGGEVPHSCTVQEWEGLGIDWYATQSQLDQAYEGFHFREAATIAMDIARAANRFLTSAEPWKAIKTDPEAAGRTMALSLNLCHALSIALYPVIPETCDRIHRMLGFKGGVDGLVRKCEPILKTLLEPALPMGHKLSPESEILFRKIEDQEIQPELQKIEQLVREAEAREAGAIEVKIEFKPAIGFDDFQKVDLRVATVRAAEKVKKASKLLKLQVQVGSTQRQVLAGVAEHYSPEEMVGKNVLLVANLAPRTIRGEISEGMLLAVEGEGGRLFMVEPQGEKINGQSVQ
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_FUSNN
Sequence: MKFFVDLNSDIGEGYGAYKLGMDEEIMKCVTSVNCACGWHAGDPLIMDKTIKIAKENNVAVGAHPGYPDLLGFGRRKMVVTPDEARAYMLYQLGALNAFAKANETKLQHMKLHGAFYNMAAVEKDLADAVLDGIEQFDKDIIVMTLSGSYMAKEGKRRGLKVAEEVFADRGYNPDGTLVNRNLPGAFVKEPDEAIARVIKMIKTKKVTAVNGEEIDIAADSICVHGDNPKAIEFVDRIRKSLIADGIEVKSLYEFIK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RSGA_STRA5
Sequence: MQGRIVKSLAGFYYVESDGVVYQTRARGNFRKKGQIPYVGDWVEFSSQDQSEGYILSIEERKNSLVRPPIVNIDQAVVIMSAKEPDFNANLLDRFLVLLEYKMIQPIIYISKLDLLDDLVVIDDIREHYQNIGYVFCYSQEELLPLLANKVTVFMGQTGVGKSTLLNKIAPELKLETGEISGSLGRGRHTTRAVSFYNVHKGKIADTPGFSSLDYEVDNAEDLNESFPELRRLSHFCKFRSCTHTHEPKCAVKEALTQGQLWQVRYDNYLQFLSEIESRRETYKKVIKRK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIAT_ECO57
Sequence: MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENTKAIPLISYEGDSFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPADNDDYAMQQLDKRDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGVLYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYSELPEEITDSPMIDRNESFTFVTGVSWRF
What are the official names of this protein?
Putative outer membrane protein YiaT.
What is the protein family that this protein belongs to?
Belongs to the MipA/OmpV family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: RL33_LEUCK
Sequence: MRIHVVLGNDETGERIYLTSKNRRNTPDRLELKKYSPKLRKVVTFKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.