PharMolix/UniProtQA huggingface dataset:
Protein: ALDOA_HUMAN
Sequence: MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY
What is the function of this protein?
Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013).  In addition, may also function as scaffolding protein (By similarity).
What are the official names of this protein?
Fructose-bisphosphate aldolase A, Lung cancer antigen NY-LU-1, Muscle-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+).
Protein: AGR3_CYCAE
Sequence: MNASPFLNESSPTRPTSFVLPDLVSHCKFPLSYHPNGDEIAQESVDWLDSSCPDLTAKQRRALRVLQSGELTAYCYNQATSPERLRVVSDFLTYLFHLDNISDGMMTRETDVLADVVMNAFWFTDKYMPTRGPGKEQLDEELNPGKLARDFWSRAIADCGVGVQARFKETMGLFFEAVNIQARMRDEDTIPDLESYIDVRRDTSGCKPSWVLIEYALGIDLPDHVVDHPIMQALNQGTNDLVTWSNDIFSYNVEQSRGDTHNMIVILMEYHGHTLQSAVDYVGELCAQTIDTFCENKERLPSWGPEIDDMVARYVKGLQDWIVGSLHWSFQTQRYFGKDGLDIKKHRFVKLLPLEAAK
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to various sesquiterpenes, including alpha-muurolene, gamma-muurolene, germacrene, delta-cadinene, delta-cadinol and cubenol.
What are the official names of this protein?
Sesquiterpene synthase Agr3, Terpene cyclase Agr3.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: GLMU_MOOTA
Sequence: MADTVAVILAAGQGKRMHSRRPKVLHRIAGRCLVEHVLAAVGEAGIKKQIVVIGHGAEEVREALGPEYTYVLQEQQLGTGHALARAREAAGTAATVLVLCGDTPLLRPATLARLLKEHRDRQAAVTILTAVLDDPTGYGRIIRDGQGMVAGIVEERDANPVEKAIREINTGIYCFEAAYLWPFLEQLQPNNDQGEYYLTDVVGLACRENLPVQAVAAGDPEEILGVNDRAQLAKAGAILRRRINMGLMQAGVTIIDPETTYIDATVRIGPDTIIYPGTFLEGNTIIEEGCSLGPGTTLRDCQVGKGSHVIHTVALESEIGPGCQVGPFAYLRPGTVLDARVKVGDFVEIKASRIGAGSKVPHLTYLGDTTVGTGVNIGAGTITCNYDGEKKWPTVIEDGAFIGSNSNLVAPVRVGAGALVGAGSTITEDVPAGSMALARGRQVNLSGRSKKSSEKRQEKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIG_DROME
Sequence: MWSRQRMRHKPLWALISLTVLLLVLDKSNANTEPVETSTTSEPDASPGCRAPDVRFTIVKPEATTEQPLAKFETTQIYLPEDFTTADVEFVDSVPRHPNENHAAVINPYSLDLGDDHLHVGDAAASLVGDDDLGDEDEDHHGDPEDKRLNANRKQGKRRRAGSGRRRRIENENGQTGRGRGSRYKRHAILHDTEASPETDRWAGSKLAAEGDVYYVHIADILKSREPNRELKSKLHKLKMKARLNKCLAEGGKEKCTRLLKKKPKKKVVEKEQTLKKEKKFPKEEQSKEKVPENGQTPKEDELELDHPETAAAHHRRRGDSHAAELDQRDRSPRWRRRRSTEFKGDLGQLPPESGIGPEPEPLADQDLKDLQQYGNQSSSARVALLWQRVKRKSGKTTGALSRPKGGGDSSSKTTSRKDKGIYDEEAGYTPIHPDDPEFDEEEEEDEEVDILQQFTEVSEIRFPGEIGPMGDRRLCKIRCVKGKWVGPLCATNEEDDNGNVKFQPLYKSCHVNRIPSHLLLSYRNISVTPIPPNRGWRKTRLSKSTLLSNTEINVGWDLPHGHSLQARCQELGIYKLLGESRVLCSNGLWAPRMPSCVPTTVLTNYSEDSAPSIRIKIFNGSHSFEPSGVMAVPPHSTVLMDCMYPRVRGTPEWSWTSWYMQYSTGWSPAQEEKAVRYRLSIKNIENNDSGTFTCTSPRGLTNSIAVVVATSTCPQLTEPLAPLKLRLEGNKLGQRAHYECPEGFRLDGAWNATCLASGNWSSPTPTCHAIQCPRLELDDPHLSLIELNTSAWGRAVFKCQWGFKLTGPAQLDCEPSGVWSGPVPRCKVIQCVMPVAPLNGRIGGTSLSQRRLTVGALVTFSCNDGHSLVGESSIICTENGQWSHSPPFCKSQCPYPGDPPNGLIAPLKFNYDAGDYLSVQCRPGFVQSYEGPPERPKCQPDGRWSGPMPKCKSYEEV
What is the function of this protein?
Plays a role in the formation of functional neural circuits from the early stages of synapse formation.  Has a role in the development of CNS functions involved in locomotor activity.
What are the official names of this protein?
Locomotion-related protein Hikaru genki.
What are the subcellular locations of this protein?
Secreted.
Protein: SDC4_HUMAN
Sequence: MAPARLFALLLFFVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
What is the function of this protein?
Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
What are the official names of this protein?
Syndecan-4, SYND4, Amphiglycan, Ryudocan core protein.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: MXMT1_COFAR
Sequence: MELQEVLHMNEGEGDTSYAKNASYNLALAKVKPFLEQCIRELLRANLPNINKCIKVADLGCASGPNTLLTVRDIVQSIDKVGQEEKNELERPTIQIFLNDLFQNDFNSVFKLLPSFYRKLEKENGRKIGSCLISAMPGSFYGRLFPEESMHFLHSCYSVHWLSQVPSGLVIELGIGANKGSIYSSKGCRPPVQKAYLDQFTKDFTTFLRIHSKELFSRGRMLLTCICKVDEFDEPNPLDLLDMAINDLIVEGLLEEEKLDSFNIPFFTPSAEEVKCIVEEEGSCEILYLETFKAHYDAAFSIDDDYPVRSHEQIKAEYVASLIRSVYEPILASHFGEAIMPDLFHRLAKHAAKVLHMGKGCYNNLIISLAKKPEKSDV
What is the function of this protein?
Involved in the biosynthesis of caffeine.  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of paraxanthine to caffeine.  Has a 5-fold preference for 7mX.
What are the official names of this protein?
Monomethylxanthine methyltransferase 1, CaMXMT1, 7-methylxanthine N-methyltransferase 1, Theobromine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAA_HALMA
Sequence: MTRIDVIDNHGQFTHLEQRALRDMGVDVSLRDNTTPPEEIDADGIVLSGGPDMDDIGNCPEYLDLDVPVLGICLGMQLIADELGGRVGGGEYGGYADVTVDILDDDDPLLGSLYPETRVWASHADEVKEVPPGFERTATSDVCGVEAMSNTDEAIYGVQWHPEVAHTEEGEEVFENFLSVCDQQSVARQ
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: GATC_STAEQ
Sequence: MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGIEPTYHVLDLQNVLRDDKAIEGIPQELALKNAKETEDGQFKVPSIMNGEDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: TMCC_DICDI
Sequence: MSSHKSTTKSSSSGSSMSLILGFSKSMEKGNYNFSKENKKNRSFGVLYAMIKGNTFPRILTIISLLIEFCQLSSFGFKQQYPWGGDAGYYLKRIMSPVSHPSNLVGYNGFTIFFWIVIGLLLLGFFNIWYVAYQFYRGKIANIWIIRTLRWFVSTTVAVLFIPIISLLLIGLDCDYSQGGILKTFSNDNIYCFKGANLSIAIVSIILIIVFSIVGFTSSATYYEYDTNVKSRFSKPHARFDVYILFVKLILALLNSLVDFSPWTTSIVYFILSITLVFGSIIILPYNNQRLNQVKSGFYTTVFWVSFMTLVTMGINDETTATTCYITIVGAFFAFPIGYFSNRFYYNWLSSKIDQLKLPTSSSTNDFNEITKNEKSKTGDSKEKESSSPSKVTWGKQPITLGSKRQIIFPFFQNKFVMSFFVEIMVRKLLRSSNGSNGDDGISSNSNESIEHANNLYQCGLQYFPNSDLLWMAYCNFLFTVRKDRHIGYAALEKLRRMKPSFDVRFFIYQRDKEREQIMDSDLRGPEHTGKIQDFVSYMEFKKLYYGAKRHHVKCLTYIKKFWGLLLHETVDLHRLSDLSGRIATTENKANESYERLLALNPNSVRVLRDYSQFLEEVVKDTESSYKLQKKAEAIEDIMSKSQTTDFKTIDIKNLDNSDTELDQVLKQESNAIQLAKIDADIERSGSKSGSSKSKDDSSESSSSSKGRRGKYKEFQQSNAINKLSWLMIGTTACCIIFLIVMLIVLRDLSVKHTHSYQGIISITDCASEAVSIAINLNTMQAISISAGSVAFPFEAAEAMITQYRKQNDRSLIIMKNIHDAIYWGEGDPTSYVGDNLSKLKSINGFDVFDIGSTIFSFEEFNRSSTLVDNKEMIDIYSTPSVNMTILVSPPGTNSTNYITVTQTYNAWKAGNSFYESALIANKMSVQDIKDRAVFDPDFKFIILNAPSNIPEMYMKIQQVYIKSLIDDINTTLDTMLYVWVAIFCFLIILGAVLFRPIVTKISREKIRTLVLFSLAPKDVVFKLSSKKIKMTSLDSGSERDNLFDTTDDDAADGIDNHEHLQVDERKKNDDIIDDGSIVNRSINFGSHRRPLMNSTNVLASTTTINRGTISNRLNEDHDKVPLIENSISNNNKGYGWDGKSKRNLNKKSLRSVLRRLHWSYVLAIFLLFGFITMGLWVTYSVVHDNTQSGYVLGKSCSRSLDSRIINYYIAELYTFDNDANENEALEAVLQLQSNHQSLPYLEDVRPLMEGSYGCWMLNKSNCITSDSIYYNDVSIGLDWLVDQYTKHSVSLVNTDPSLLSTSPELGWMQAIGSDVVFQGLDTATFTYFQYYLSQKDWATKVLTSVLAISCVLLLVIHLLLFRPFMNHLRIQHIHTLALLRLAPDDIRFMEVSDKVIDED
What are the official names of this protein?
Tiny macrocysts protein C, Gamete enriched gene 10 protein, HAT repeat-containing protein tmcC.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL10_BACHK
Sequence: MSKVIETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKDHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVADQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL27_VEREI
Sequence: MAQKKGGGSTRNGRDSQPKMLGVKVFGGQRITAGSIIVRQRGTRFHPGSNVGMGKDHSLFALVDGQVSFGIKGALSKPTVNVTPAASAPPV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YCF4_PROMA
Sequence: MSADFKEASSPTDSSETLLEQIVKGSRKTSNYIVASMLAVGGIGFSLASLSSYFGIDLLPLGNPSTLIFVPQGLFMGFYGIAATFISVYLWALIKVDYGSGLNRFDKNKGVLSVSRKGLLKEILVEIPIDDIQAVKLEVREGFNPRRRITLRLQGRRDLPISEVGGPQPLLSLEQEGAEIARFLKVNLEGLSN
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: RL24_PSET1
Sequence: MAAKIRRDDEVIVLAGKDKGKRGKVLSVVTESGRLFVEGINLIKKHQKPVPQLNQPGGIVEKEASIDVSNVAIYNSETSKADRVGFKIEDGKKLRIFKSTGKTI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y2695_ROSDO
Sequence: MILTTTNTIEGHTITAYKGIVVGEAIMGANIVRDFFASVTDVIGGRSGAYEDKLQDARTEAMAEIEERAAALGANAVVGIDLDYEVTGDSMLMVSVSGTAVTIT
What are the official names of this protein?
UPF0145 protein RD1_2695.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: HIS6_NOSS1
Sequence: MLSKRILPCLDVKAGRVVKGVNFVDLKDAGDPVELAKVYNDAGADELVFLDITATHEDRDTIIDVVYRTAEQVFIPLTVGGGIQSLENVKALLRAGADKVSINSAAVRDPELIDRASDHFGNQCIVVAIDARRRVDPSNPGWDVYVRGGRENTGLDALSWAKEVEKRGAGELLVTSMDADGTQAGYDIELTRAIAESVEIPVVASGGAGNCEHIYTALTEGKAEAALLASLLHYGQLSVAEIKNYLHESQVPVRLYTQF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_ACIBC
Sequence: MAIQEIRHPLIRHKLGLLRRADISTKNFRELAQEVTMLLTYEATKDLPVVDCEIEGWAGNVTTQRIAGKKITIVPILRAGIGMLDGVLNLIPSAKVSVLGLERDEATLEVRTYYKKLVPDVANRIAMIIDPMLATGNSLVAAIDVLKASGCKDIRVMVLVAAPEGIAKVEAAHPDIQLYTASIDNGLNEHGYIVPGLGDAGDKIFGSVQKD
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: FANC_ECOLX
Sequence: MKKTLLAIILGGMAFATTNASANTGTINFNGKITSATCTIDPEVNGNRTSTIDLGQAAISGHGTVVDFKLKPAPGSNDCLAKTNARIDWSGSMNSLGFNNTASGNTAAKGYHMTLRATNVGNGSGGANINTSFTTAEYTHTSAIQSFNYSAQLKKDDRAPSNGGYKAGVFTTSASFLVTYM
What is the function of this protein?
FanC is the main component of the K99 fimbriae.
What are the official names of this protein?
K99 fimbrial protein.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: ISK1L_CHICK
Sequence: SIPPACDKYSRLPGCPRDYSPVCGTDGKTYPNECVLCLSNSEENKNVQIYKSGMC
What is the function of this protein?
Inhibits trypsin and plasmin.
What are the official names of this protein?
Trypsin inhibitor ClTI-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_HYDS0
Sequence: MAVPKRRTSRWRRNQRRAQAFFAKLKSFNMVKCPNCGEFAMPHRACPYCGYYRDKQVLEV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LOLD_NITOC
Sequence: MNNTEQEMVLWCRDLARKFTDGYLSVEVLREVNLSIAPRECVAIIGASGSGKSTLLHLLGGLDRPTQGQVWIAGQNLARLNDTERGRLRNRALGFIYQLHHLLPEFTALENTALPLLIAGASTANAQKKAMALLQRVGLEARFNHKPGELSGGERQRAAVARALVTDPRCVLADEPTGNLDRKNAEQVFKLMLDLNHELGTALVIVTHDIHLAAQTDRVLTLMDGRLVQEPLP
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CARDF_CYNCA
Sequence: ADSGSAVVALTNDRDTSYYGEIGIGTPPQKFTVIFDTGSSVLWVPSSKAHSMYESSGSSTYKSQDSVTIGDLVVKEQDFIEATEEADNVFLNRLFDGILGLSFQTISVPVWYNMLNQGLVKRFSFWLNRNVDEEEGGELVFGGLDPNHFRGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAIGANGSEELNVKFGLTPEQYILKGEATQCISGFTAMDATLLGPLWILGDVFMRPYHTVFDYGNLLVGFAEAA
What is the function of this protein?
Aspartic protease with a high preference for bonds between hydrophobic residues.
What are the official names of this protein?
Cardosin-F.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Microsome membrane. Protein storage vacuole. Secreted, cell wall. Secreted, extracellular space, extracellular matrix. Note=Procardosin-F is associated with the microsomal membranes, the mature form is secreted.
Protein: PHS_DROVI
Sequence: MVAKLTEQERVEKLQPLLDAGWCLVEGRDAIYKEFLFKDFNQAFSFMTGVALLAEKMNHHPEWFNVYNKLQVTLSTHDVGGLSSQDIRMATYLETQAKLLH
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: NDPA_ESCF3
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTDTVSEMVAELHRVYSAKNKAYGLFSEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLICVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGN
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ZAPB_ECO55
Sequence: MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: PTHD4_MOUSE
Sequence: MCFLRRPGAPASWIWWRMLRQVLRRGLQSFCHRLGLCVSRHPVFFLTVPAVLTITFGLSALNRFQTEGDLERLVAPSHSLAKIERSLASSLFPLDQSKSQLYSDLHTPGRYGRVILLSSPGDNILLQAEGILQTHRAVMEMKVNHKGYNYTFSHLCVLRNQDKKCVLDDIISVLEDLRQAAVSNKTTARVQVRYPNTKLKDGRNSFIGHQLGGVVEVPNSKDQRVKSARAIQITYYLQTYGSATQDLIGEKWENEFCKLMRKLQEEHQDLQLYSLASFSLWRDFHKTSILTRSKVLVSLVLILTTATLSSSMKDCLRSKPFLGLLGVLTVCISIATAAGIFFITDGKYNSTLLGIPFFAMGHGTKGVFELLSGWRRTKENLPFKDRVADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKIFCQNMCVSILLNYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDRKPVWFQTVMSDGHQQTSHHETNPYQHHFIQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGASIINLLASDSPSVSYAMVQQKYFSNYSPVIGFYVYEPLEYWNSSVQEDLQRLCSGFTAVSWVEQYYQFLKTSNISANNKTDFISVLQSSFLKKPEFQHFRNDIIFSRAGDENNIIASRLYLVARTSRDKQKEVIEVLDKLRPLSLSKSIRFIVFNPSFVFTDHYSLSVTVPVLIAGFGVLLVLILTFFLVIHPLGNFWLILSVTSIELGVLGLMTLWNVDMDCISILCLIYTLNFAIDHCAPLLYTFVLATEHTRTQCIKSSLQEHGTAILQNITSFLIGLLPLLFVPSNLTFTLFKCLLLTGGCTLLHCFVILPVFLTFFPPSKKHHKKKKRAKRKEREEIECIEIQENPDHVTTV
What is the function of this protein?
Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells.
What are the official names of this protein?
Patched domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PCP_CLOBB
Sequence: MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKPDILISIGQAGGRFGITPERVAINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMVKEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIKGGFIHVPYIPSQVVNKPNMPSMSIEDISKGLELSVKAAVENNTDIKTAQGEIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_MYCSK
Sequence: MRDELVWIDCEMTGLDLRSDLLIEIAVLVTDADLNILGDGLDVVIHAPDEALDAMIPVVTEMHTRSGLIEEVRASTVDLATAEEMVLDYIRGHVKQAKTAPLAGNSIATDRGFIARDMAKLDDYLHYRMIDVSSIKELCRRWYPRIYFGQPEKGLAHRALADIHESIRELKYYRQTAFVAPPGPSTSDIAAIAAELGPPGKDAADTDSAAGHTTG
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGA_ECOLI
Sequence: MKTSDNERIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAEEDAFRRDLIDSIIRDFSNSDSGGPNRRTATADNKSMFNGKKINRIH
What is the function of this protein?
Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway.  May serve to stimulate biofilm maturation, probably via the Rcs phosphorelay.  Mild overexpression at 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression.  Both of these effects require RcsB.
What are the official names of this protein?
Probable two-component-system connector protein YmgA.
Protein: RECR_FRATN
Sequence: MTSKIFSPKISAVIESLRKLPTIGKKSSQRLALYLLDKSPETARAIANSLLDATANIKKCVYCQALTEDDVCNICSNTNRDDTKLCIIESMLDMIAIEEAGIYRGKYFVLNGRISPLDGVGPSELKLDILQRIIADRKIDEVILAISPTVEGETTAHFISQMIAKDIKISRIGFGVPFGGELEYLDQQTLLHAFNARTNI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TONB_KLEAK
Sequence: MTLDLPRRFPWPTLLSVAIHGAVVAGLLYTSVHQVIEKPSPSQPIEITMVAPADLEPPQAAQPVVEPVVEPEPEPEPEVVPEPPKEVPVVIHKPEPKPKPKPKPKPKPEKKVEPKREVKPAEPRPVSPFENNNTAPARTAPSTTAATAKPMTTAPSGPKALKRGDPSYPQRAQALRIEGDVRVKFDVTADGRVENIQILSAKPANMFERDVKTAMRKWRYEAGRPGTGLTMNIKFRLNGVKMD
What is the function of this protein?
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.  It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
What are the official names of this protein?
Protein TonB.
What is the protein family that this protein belongs to?
Belongs to the TonB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: MRAY_RICBR
Sequence: MLYNLLLPYIHNSHIANLFHYITFRSGLAVLVTLSLSFLIGPRLIKFLQTLQKYGQPIRLDGPESHQAKAGTPTMGGIMIILSSCFSTLLLADLTNKYIWITLFGFVSFGIIGFLDDYAKVTKNNHYGVKGKSKLLLQGIISLIVCILLEYTIDSPSHMLNVPFFKSLSMDLGYLYIFFAIFVIVGASNAVNLTDGLDGLATVPIALTAGSFALISYLVGNLIYSNYLQLTYLPNTGELTIFCASIVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLGIVGGLFVIETISVIMQVYYFKATKGKRIFKMAPLHHHFEKSGWTESKVVIRFWIISLIFVLIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.