PharMolix/UniProtQA huggingface dataset:
Protein: HSFA2_ARATH
Sequence: MEELKVEMEEETVTFTGSVAASSSVGSSSSPRPMEGLNETGPPPFLTKTYEMVEDPATDTVVSWSNGRNSFVVWDSHKFSTTLLPRYFKHSNFSSFIRQLNTYGFRKIDPDRWEFANEGFLAGQKHLLKNIKRRRNMGLQNVNQQGSGMSCVEVGQYGFDGEVERLKRDHGVLVAEVVRLRQQQHSSKSQVAAMEQRLLVTEKRQQQMMTFLAKALNNPNFVQQFAVMSKEKKSLFGLDVGRKRRLTSTPSLGTMEENLLHDQEFDRMKDDMEMLFAAAIDDEANNSMPTKEEQCLEAMNVMMRDGNLEAALDVKVEDLVGSPLDWDSQDLHDMVDQMGFLGSEP
What is the function of this protein?
Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).  Seems to be involved in other environmental stress responses.  Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs).  Binds to the promoter of SGIP1 and activates its expression in heat acclimated plants (PubMed:30778176).  Involved in the mechanisms necessary for quick response to heat and subsequent heritable transgenerational memory of heat acclimation (global warming) such as early flowering and attenuated immunity; this process includes epigenetic regulation as well as post-transcriptional gene silencing (PTGS) (PubMed:30778176).  In response to heat, HSFA2 is activated and promotes the expression of REF6 which in turn derepresses HSFA2, thus establishing an heritable feedback loop able to trigger SGIP1 and subsequent SGIP1-mediated SGS3 degradation; this prevents the biosynthesis of trans-acting siRNA (tasiRNA) and leads to the release of HTT5, which drives early flowering but attenuates immunity (PubMed:30778176).
What are the official names of this protein?
Heat stress transcription factor A-2, AtHsfA2, AtHsf-04.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: WSB1_HUMAN
Sequence: MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWATPRQVPSLQHLCRMSIRRVMPTQEVQELPIPSKLLEFLSYRI
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes type II iodothyronine deiodinase/DIO2.  Confers constitutive instability to HIPK2 through proteasomal degradation.
What are the official names of this protein?
WD repeat and SOCS box-containing protein 1, WSB-1, SOCS box-containing WD protein SWiP-1.
Protein: NADA_AGRFC
Sequence: MLTMRICLRATYTQKEYKWESTVNEQISAASLYDRVARVIPKAEWMGFQDDVEAILELKRKRNAVILAHNYQTPEIFHGVADIVGDSLALARKAMEVEADVIVLAGVHFMAETAKLLNPEKTVLIPDMAAGCSLADSITPEDIALLRKAYPGVPVVTYVNTSAAVKAASDICCTSGNARQVVESLGVPRVLMLPDEYLAKNVAKETSVELIAWRGHCEVHELFTADDIRELRESHPGVIVLAHPECPPEVVDAADFSGSTAVMSDYVGRERPARVVLLTECSMSDNVAVHHPDVEFIRPCNLCPHMKRITLGNIRTALEENRHEVTVDPAIAGAARRAVERMLQI
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_METRJ
Sequence: MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEAALKKILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLYIHGDRNKDAPASVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ATPA2_ALBFT
Sequence: MEPAEDLQKVFDKAFAGMREAREAFAPSLAPREVGTITSIATGIAKVSGLPGVGFDELVKFPGDLFGIAFNVDEAEIGVVLLGEYWHLHAGDEVDRTGRVMDVAVGDGLLGRVIDPLGRPLDGRGPVASSHRLPIERPASPIMDRAPVTVPLQTGLKVIDALIPVGRGQRELILGDRQTGKTAIAIDTILNQQGQNVLCVYCAIGQRASAVAKVVATLREKGAMDFTTVVVTEGNDPPGLAYIAPYAATSIAEHFMEAGRDVLIVYDDLTQHARAYRELSLLLRRPPGREAFPGDIFYIHSRLLERATHLRQERGGGSLTALPIIETQAQNISAYIPTNLISITDGQIYLSPSLFELGVLPAVDVGKSVSRVGGKAQRTAYRAVAGDLKLAYAQFEELETFARFGARLDENTTKIIEHGRRIRACLKQPESAPVSVAAQIAVLLALSAELFDGVELNQMTEAEQAVRAAAADMPAEVRARFDSADKLSDEDREAIIQIARVALASFQPAPEPETAPKTKTDIKPKPKAAGGESS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF2_VIBVU
Sequence: MTQLTVKALSEEIGTPVDRLLEQLADAGMKKSSSDQVSDEEKQKLLTHLKKEHGDTSGDAEPTRLTLQRKTRSTLSVNAGGGKSKDVQIEVRKKRTYVKRSAIEDEAKREAEEAAQREAEEAAKRAAEEAAKREAEEAAKREAEEKAKREAEEAAKREAEKSVDRDAEEKAKRDAEGKAKRDAEEKVKQEAARKEAEELKRRQEEEAKRKAEEESQRKLEEAREMAEKNKERWSAAEENKGDMEDTDYHVTTSQYAREAEDEADRKEEEARRRKKKTKSSAKASENDERGGPRVQRGGKGGRKGKLSKPKSMQHGFDKSAVVAKSDVVIGETIVVSELANKMSVKATEVIKIMMKMGAMATINQVIDQETAQLVAEEMGHKVVLRKENELEEAVLSDRDNMFEAVPRAPVVTIMGHVDHGKTSTLDYIRRTHVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAQATDIVVLVVAADDGVMPQTVEAIQHAKAAGVPLIVAVNKIDKEEANPDNVKNELSQYNVMPEEWGGENMFVHISAKQGTNIDQLLETILLQAEVLELTAVKDGMASGVVVESRLDKGRGPVATVLVQSGTLRKGDIVLCGQEYGRVRAMRDEIGNEVNEAGPSIPVEILGLSGVPAAGDEATVVRDERKAREVANYRAGKFREVKLARQQKSKLENMFSNMAAGDVAELNIVLKADVQGSVEAIADSLTKLSTEEVKVNIVGSGVGGITETDAVLAEASNAIILGFNVRADASARRAIEAASIDLRYYSIIYQLIDEVKQAMSGMLAPEFKQEIIGLAEVRDVFKSPKLGAIAGCMVTEGLIKRNAPIRVLRDNVVIYEGELESLRRFKDDVAEVKNGYECGIGVKNYNDVRVGDQIEVFETIEIKRTID
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STAAB
Sequence: MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TYDC1_PETCR
Sequence: EFRRQGHLMIDFLADYYRKVENYPVRSQVSPGYLREILPESAPYNPESLETILQDVQTKIIPGITHWQSPNFFAYFPSSGSTAGFLGEMLSTGFNVVGFNWMVSPAATELENVVTDWFGKMLQLPKSFLFSGGGGGVLQGTTCEAILCTLVAARDKNLRQHGMDNIGKLVVYCSDQTHSALQKAAKIAGIDPKNFRAIETSKSSNFKLCPKRLESAILYDLQNGLIPLYLCATVGTTSSTTVDPLPALTEVAKKYKLWVHVDAAYAGSACICPEFRQYLDGVENADSFSLNAHKWFLTTLDCCCLWVRDPSALIKSLSTYPEFLKNNASETNKVVDYKDWQIMLSRRFRALKLWFVLRSYGVGQLREFIRGHVGMAKYFEGLVGMDNRFEVVAPRLFSMVCFRIKPSAMIGKNDEDEVNEINRKLLESVNDS
What are the official names of this protein?
Tyrosine decarboxylase 1, ELI5.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: CSPA_SALTI
Sequence: MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKSLDEGQKVSFTIESGAKGPAAGNVTSL
What is the function of this protein?
Binds to and stimulates the transcription of the CCAAT-containing, cold-shock-inducible promoters of the H-NS and GyrA proteins.  Binds also to the inverted repeat 5'-ATTGG-3' (By similarity).
What are the official names of this protein?
Cold shock protein CspA, CSP-A, 7.4 kDa cold shock protein, CS7.4.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPW_MOUSE
Sequence: MAPSTTVTRRVKRKAPRAFLKRTLKQKKPHLGLGRCCDLLIHLNCLLFIQRLAEESRTNACESKSRVIKKDHVLAAGKVILKKSRG
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity).  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity).  Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA.  Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.  CENPW has a fundamental role in kinetochore assembly and function.  It is one of the inner kinetochore proteins, with most further proteins binding downstream.  Required for normal chromosome organization and normal progress through mitosis (By similarity).
What are the official names of this protein?
Centromere protein W, CENP-W, Cancer-up-regulated gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the CENP-W/WIP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Nucleus matrix. Nucleus, nucleolus. Note=Constitutively localizes to centromeres throughout the cell cycle, and to the inner kinetochore during mitosis.
Protein: PHR3_ORYSI
Sequence: MSTQSVIAVKQFSGPDKIAQAYTVPQPSAHVLSNANYDYDLCGSTNSTSLSCAIQSSNIKTESISSSSLPKILPFSTDSNGESSLSRMSQAEFSDPILSSSSTFCTSLYTSSPMNSGSCRKTGYLPFLPQPPKCEQQQNSVGQSSSSLMLLDADLRNSGHADDEHTDDLKDFLNLSSDCSFHGKCSAMAYNEQMEFQFLSEQLGIAISNNEESPRLDDIYDRPPQLMSLPVSSCSDQEDLQDARSPAKVQLSSSRSSSGTASCNKPRLRWTPELHERFVDAVNKLEGPEKATPKGVLKLMKVEGLTIYHIKSHLQKYRLAKYLPETKEDKKQEEKKTKSVANGNDHAKKKSAQMAEALRMQMEVQKQLHEQLEVQRQLQLRIEEHARYLQKILEEQQKARESISSMTSTTEGESPEFAPMEKTEDKAETSSAPLSKCRITDTDAECHSKVDNKKTKPQADLEMVHDE
What is the function of this protein?
Transcription factor involved in phosphate starvation signaling.  Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes.  Functionally redundant with PHR1 and PHR2 in regulating Pi starvation response and Pi homeostasis.
What are the official names of this protein?
Protein PHOSPHATE STARVATION RESPONSE 3, OsPHR3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_OENOB
Sequence: MADLKITLIKSIVHREPRQREIAKSLGLGRVHSSVVRPDNAATRGIIFKIAHLVSVEEVNK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RTG1_YEAST
Sequence: MSSIPAGTDPGSCGANFKNDRKRRDKINDRIQELLSIIPKDFFRDYYGNSGSNDTLSESTPGALGLSSKAKGTGTKDGKPNKGQILTQAVEYISHLQNQVDTQNREEVELMVKATQLAKQTGTIVNDINLENTSAEVALSRIGVGPLAATNDDSVRPPAKRLSSFEYGGYGEYGNGS
What is the function of this protein?
Required for a novel path of interorganelle communication between mitochondria, peroxisomes and the nucleus, thereby maintaining a functional metabolic interaction between the tricarboxylic acid and glyoxylate cycles.  Transcription factor that regulates CIT2 gene expression.  Binds to two identical sites oriented as inverted repeats 28 bp apart in a regulatory upstream activation sequence element (UASR) in the CIT2 promoter.  The core binding site is 5'-GGTCAC-3'.
What are the official names of this protein?
Retrograde regulation protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF62_ARATH
Sequence: MATRLQFENNCEVGVFSKLTNAYCLVAIGGSENFYSAFESELADVIPIVKTSIGGTRIIGRLCAGNKNGLLVPHTTTDQELQHLRNSLPDQVVVQRIDERLSALGNCIACNDYVALAHTDLDKETEEIIADVLGVEVFRQTIAGNILVGSYCALSNKGGMVHPHTSVEDLEELSTLLQVPLVAGTVNRGSEVIAAGMTVNDWTSFCGSDTTATELSVIDSIFKLREAQPSSIVDEMRKSLIDTYV
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6-2, AteIF-6;2.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: DEOC_BACCN
Sequence: MNIAKLIDHTVLKPNSKKEDVMKVIEEAKKYNFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGANTTETKVFETKDVIAKGATEVDMVINVGALKDGDDEFVEKDIREVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMIEAGASRIGASASVAIVLNDEKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLD3_MACFA
Sequence: MKPKLMYQELKVPAEEPANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAPKGVNVRIAVSKPNGPQPQTDLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYIAVMNYLPTLEFSHPHRFWPAIDDGLRRAAYERGVKVRLLVSCWRHSESSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVMQNGRGSLRSQLEAIFLRDWDSPYSHDLDASADSVGNACRLL
What is the function of this protein?
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity).  Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity).  May be important in myotube formation.  Plays a role in lysosomal homeostasis.  Involved in the regulation of endosomal protein sorting (By similarity).
What are the official names of this protein?
5'-3' exonuclease PLD3, Choline phosphatase 3, Phosphatidylcholine-hydrolyzing phospholipase D3, Phospholipase D3, PLD 3.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Lysosome lumen. Early endosome membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Localizes to ER-associated vesicles in differentiating myotubes. The soluble form in lysosome arises by proteolytic processing of the membrane-bound form.
Protein: LFTR_BURL3
Sequence: MVPWLGPDDPFPPIERALGPATGAPGLLAASADLLPSRLIDAYLRGIFPWYSDGQPVLWWSPDPRMILVPAEFKVSPSLRKTLKRVLREPEWEVRVDHDFPGVMRACAQAPRRGQRGTWITAEIIDAYTSLYRSGNAHSIETWHDGRRVGGLYGVSFGRMFFGESMYADATDASKIALATLVAHLREQGLEMIDCQQNTSHLASLGGREIARKAFVAHVRSAVAEPPIPWQFDKRVLAALTGRAEAAAPSGIER
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_CHLCH
Sequence: MKSHEIRQSFLDFFAQKGHTIVRSAPVIPADDPTLLFTNAGMNQFKDVFLDKGSRPYVRAADTQKCIRASGKHNDLEDVGRDTYHHTFFEMLGNWSFGDYYKLEAITWAWELFTVVWKLPKERLYATVYQDDDESFQIWKEQTDINPDHILRFGDKDNFWEMGETGPCGPCSEIHIDLTPDGSGKELVNVGDYRVIELWNLVFIQYNRQSDGHLEPLPKKHVDTGMGFERIVAVMQGKGSNYDSDVFQPLFDKITEITGVRYGASLDAPNDIAMRVIADHARTLTFALSDGAMPSNEGRGYVLRRILRRALRYSRNLGYHQPILHQLVGTLALAMGEVFPELVQRQEAVSAIIKAEEESFIVTLDRGIDLFSELVEKLRASNGKVIAGSDAFRLYDTYGFPFDLTRLMAADEGFEVDGEGFEHCMQEQKNRARSDRREKQRVDDDGAKWQWFSDVRASQFVGYDHLVHSATITGIRQGNGKLLLVLDATPFYAESGGQTGDNGWLENSRYRLHVADTVKDGDAIVHVVSDAFDKVQDSAVQPEDVEIVEQELAVAASVHRTARQDAERNHTATHLMHAALRRILGEHVQQKGSFVSPERLRFDFSHFSKLTDEEIEAVEIAVNTQIREAEPVVKHADVLFDDAVAKGALAFFGDKYADRVRVVEIPGMSVELCGGTHVDNIGRIGLFKIISEASVASGVRRIEAVTGKAAEKLLWQEYRELQQIRQLLKAKGDEAVVEKVAGLMDSKKELEKELAESRAAALVEQLTAALQAAPEVSGCRVLAIEVKNNDGETMRQATMALRDKAPCAVGLLATVEAGKVVLVSFATDEAVRTCSLDAGALIREAAKQVQGGGGGKAEFATAGGKQPENLSKALDAFTAAVRAKLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_STRR6
Sequence: MVNHFRIDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGDLSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEYGNKIDEMLRNLDKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_NOVAD
Sequence: MSNSVPSSVRGKLTPDAPLAPLVWFKSGGTADWLFEPRDVADLQDFLAGLAPEVPVMALGLGSNLIVRDGGVPGVVIRLGKAFAKVAKVDEVTLDCGGGASGILVSSTARDNGIAGLEFLRSIPGTVGGFVRMNGGAYGREVKDVLVDCDVVIRSGEIVTLPLSELGYTYRHSNLTDGSIVVAARFRGHPGNPEAIQAEMDRISAAREASQPLRSKTGGSTFKNPDGGKAWELVDKAGCRGLQIGGAQVSEKHTNFLINTGTATSAEIEGLGEEVRRRVKASSGVDLEWEIKRIGRP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_XANCP
Sequence: MTRQNAYSRDQLLASARGELFGPNSGRLPNDPMLMFDRITEINDNGGSHGKGLIRAELDIRPDLWFFNCHFIGDPVMPGCLGLDAMWQLTGFFLTWIGAPGRGRALGCGEVKFTGQVLPTATLVTYEIEISRVINRKLVMAQSDARMLVDGREIYAAKDLRVGMFTSTENF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_SODGM
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQTPY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBC3C_HUMAN
Sequence: MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
What is the function of this protein?
Acts as a GTPase activating protein for RAB5.  Does not act on RAB4 or RAB11 (By similarity).
What are the official names of this protein?
TBC1 domain family member 3C.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.
Protein: RL30_POLSJ
Sequence: MTKEAKVKVQLVRSPIGTKESHRATVRGLGLRGVNSVSELQDTPAVRGMINKISYLVKVI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ODBB2_ARATH
Sequence: MAAALVRRFCRGSSFPVSGHGYRMLSTVENVSESGKSMNLYSAINQALHIALETDPRSYVFGEDVGFGGVFRCTTGLAERFGKSRVFNTPLCEQGIVGFGIGLAAMGNRVIAEIQFADYIFPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSSIRDPNPVVFFEPKWLYRQAVEDVPEDDYMIPLSEAEVMREGSDITLVGWGAQLTIMEQACLDAENEGISCELIDLKTLIPWDKEIVETSVRKTGRLLISHEAPVTGGFGAEIAATIVERCFLRLEAPVSRVCGLDTPFPLVFEPFYMPTKNKILDAIRSTVNY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).  Required during sugar starvation and acts under the control of a sugar-sensing mechanism involving Ser/Thr kinases and phosphatases.
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta 2, mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDE1B, BCKDH E1-beta, Protein DARK INDUCIBLE 4.
What are the subcellular locations of this protein?
Mitochondrion matrix.