PharMolix/UniProtQA huggingface dataset:
Protein: METE_NEIG1
Sequence: MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLDVAKDLREKNWKHQAAANADYVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLPLEQFFQLARGNKDQFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQTLGLKAKPTVVGPLTFLWVGKEKGSVEFDRLSLLPKLLPVYVEILTALVEAGAEWIQIDEPALAVDLPKEWVEAYKDVYATLNKVSAKILLGTYFGSVAEHAALLKSLPVDGLHIDLVRAPEQLDAFAGYDKVLSAGVIDGRNIWRANLNKVLETVGPLQAKLGERLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPVNAGQRKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSASDYEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAMTVAWSTYAQNLTKRPMKGMLTGPVTILQWSFVRNDIPRATVCKQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLAAFGEFKYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTRKLRAELAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: AROB_BURM7
Sequence: MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWETLNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRVDKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5HT1D_TAKRU
Sequence: MELDNNSLDYFSSNFTDIPSNTTVAHWTEATLLGLQISVSVVLAIVTLATMLSNAFVIATIFLTRKLHTPANFLIGSLAVTDMLVSILVMPISIVYTVSKTWSLGQIVCDIWLSSDITFCTASILHLCVIALDRYWAITDALEYSKRRTMRRAAVMVAVVWVISISISMPPLFWRQAKAHEELKECMVNTDQISYTLYSTFGAFYVPTVLLIILYGRIYVAARSRIFKTPSYSGKRFTTAQLIQTSAGSSLCSLNSASNQEAHLHSGAGGEGGGSPLFVNSVKVKLADNVLERKRLCAARERKATKTLGIILGAFIICWLPFFVVTLVWAICKECSFDPLLFDVFTWLGYLNSLINPVIYTVFNDEFKQAFQKLIKFRR
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.  Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity.  May also play a role in regulating the release of other neurotransmitters.  May play a role in vasoconstriction (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 1D, 5-HT-1D, 5-HT1D, 5HT1D, F1D, Serotonin receptor 1D.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUT_ECOUT
Sequence: MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDNFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CEP44_MOUSE
Sequence: MATGDLKRSLRKLEQVLRSLNYPNEVDYVGLIKGDTAASLPIISYSLTSYSPYVAELLMESSIELIAKNDVRFTDTVYKLLRDQFDYKPILTKKQFIQSGFAEWKIEIVCDILNCVMKKHKELIGLDKNSSCQRKKNVSEKPEPCSNSEKRPAEAVGIDITGRFMTSGKKKAVVIRHLYTDEKVGVPEGTVTLADISQGCSESAEQSSDIRIPEAQDPEVKAELQDICDHPEITALQIALAECQEKLKQLTWIEKRLERLEAATHGKVMVDEKAWNNLLSRVTLLETEMLLSKKSESVERNVASQDCESISDVDFVPYDKNYSVGGAAGNYRSSGCSAVSSETAPGSSIVNYCVLREFSEETTIQKMERMKKMFEETAELLKCSSR
What is the function of this protein?
Centriole-enriched microtubule-binding protein involved in centriole biogenesis.  In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall.  Functions as a linker component that maintains centrosome cohesion.  Associates with CROCC and regulates its stability and localization to the centrosome.
What are the official names of this protein?
Centrosomal protein of 44 kDa, Cep44.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Localizes to the proximal end of mother and daughter centrioles.
Protein: MLPJ_BORBU
Sequence: MKIINILFCISLLLLNSCNSNDNDTLKNNAQQTKSRKKRDLSQEELPQQEKITLTSDEEKMFTSLINVFKYTIEKLNNEIQGCMNGNKSKCNDFFDWLSEDIQKQKELAGAFTKVYNFLKSKAQNETFDTYIKGAIDCKKNTPQDCNKNNKYGDGDNLIEQYFRGVANDMSNRNSNEEIYQYLKDELLKEDNHYAGLTANWQN
What is the function of this protein?
An outer membrane protein that may participate in pathogenesis.  Some human Lyme disease patients have antibodies against this protein (PubMed:10948116).  The Mlp proteins probably undergo intragenic recombination, generating new alleles (Probable).
What are the official names of this protein?
Lipoprotein MlpJ.
What is the protein family that this protein belongs to?
Belongs to the Multicopy lipoprotein (Mlp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: APHA_HAEP3
Sequence: MKNLLKLSAIAILAASAVSTFASNKEPYTEQGTNAREMTEQKPIHWISVEQLKKELEGKAPINVSFDIDDTVLFSSPCFYHGQEKYSPGKNDYLKNQDFWNEVNAGCDQYSIPKQIAVDLINMHQARGDQIYFITGRTAGDKDGVTPVLQKAFNIKDMHPVEFMGGRKLPTKYNKTPGIIEHKVSIHYGDSDDDILAAKEAGIRGIRLMRAANSTYQPMPTLGGYGEEVLINSNY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters.  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRMD_FRATN
Sequence: MKFGIISIFPEMFKAINDFGVTARAIKDSKVSISCFNPRDYTTDRHATVDDTSFGGGAGMVMKYQPLSAAIEDAKNTLGCGTKVVYLSPQGSIFNHRKAQELLQNDSLILLCGRYEGVDERLIQDYVDEEISVGDFVLSGGELPAMLVMDSLIRLIPEVLGNKESVIEDSFYDGLLDYPHYTKPAVLPNGNAVPGVLLSGNHKEIAKWRRKQKLIRTYERRKDLIECLCLSAQDKQILDDYKIDKVSTKGEE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM1_USTMA
Sequence: MSFHPNAVDAPPSYLHQHQAGSPLYTQNTIRPNANSTDLNSPHKPPILQPWLGLQARLFLAPISIPLISLLFVAARMLSSSNEATDSISSAKGKLLSACSAAEGTASLAASFPHFLAASTNVQLALSVTATVHSAARVFDLSMTAIQKILTYIVNSYKSLFMCFMELLVRGALAVLITAVEFISQAITAATLGIRSAIQESITGVNTLLATAVGAINDVIGVFGQHVNPPHIAVPSLTSLENITLPHEIQDGLVKLNATLPTLQQLKQSMDALIETPFEEMKREVNATLASFQFNHSVFPVPEMQNVTFCDRIDTSPLDELGNALKNVARWGLVALLLIAIVVMLIGVAWEWWKWQKEVKAVERTRSLWLAQRSSAHSDGNDKFCDNILKTENLMSLLTISQHPLISFCSLNYCKRLGIRTRRAQDRCAWLLSFLMHPASLACLFTGVLGLISVLMQAILVHSLSHHYVSSIDTSLAHLSSDIVNLVHDHTRNASVAFSTSANTVILQVEAELNDHVFRWVDTTTSTMNSTLNQFVDGLTETLTSTFGGTPFNAPLQTFVQCILGQKVQGIEKALTWIHENAYVNFSVVPADVLMLRPEQQEAVLRPVREAMLGSRDDQGGGNGVVGHVISRYMEHLHQEKILFTALIGVYAIILLIGLLAVLYATLAERRMHDDDETRKKVSRDESEEKLRSDLQAGPGGAGIARLWSRRPKLNAGCFRAFSHPPVPVSAQNPSSKIDHAARFPSSAHSSRPDPIHVTKDSISYPFQMHHSLNTSPSTRPTQPTPLQQTSNPDRDTVQSLHHASTTHNQTASTRTKEYDSWLCFLASYHDGEATVPAKAPEAVEGAQDRFHRLFGCSLRASPTVATFNHHVSAPAVSSDRAEIEVEDARFRETLDLGSMQDWIGSKSPIPPPAGRGGSHSPRNTADQLPEVQLTRSGGCVGPHSSDSTQETYAFTDSVRLPPGPQPQQKRVVSSQSISFFAW
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PMF1_HUMAN
Sequence: MAEASSANLGSGCEEKRHEGSSSESVPPGTTISRVKLLDTMVDTFLQKLVAAGSYQRFTDCYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGNLEAVLNALDKIVEEGKVRKEPAWRPSGIPEKDLHSVMAPYFLQQRDTLRRHVQKQEAENQQLADAVLAGRRQVEELQLQVQAQQQAWQALHREQRELVAVLREPE
What is the function of this protein?
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.  May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
What are the official names of this protein?
Polyamine-modulated factor 1, PMF-1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Protein: RBL_SCUBO
Sequence: SVGFKAGVKEYKLTYYTPXXXAKDTDILAAFXVTPQPGVPPEEAGXXVAAESSTGTWTTVWTDGLTSLDRXKGXCYHIEPVIGEKDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLRKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNAIIREASKWSPELAAACEVWKEIKFEFAAMDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRPC_CUPNE
Sequence: MSEAQPLVTPKPKKSVALSGVTAGNTALCTVGRTGNDLHYRGYDILDIAETCEFEEIAHLLVHGKLPTKSELAAYKAKLKSLRGLPANVKAALEWVPASAHPMDVMRTGVSVLGTVLPEKEDHNTPGARDIADRLMASLGSMLLYWYHYSHNGRRIEVETDDDSIGGHFLHLLHGEKPSALWERAMNTSLNLYAEHEFNASTFTARVIAGTGSDMYSSISGAIGALRGPKHGGANEVAFEIQKRYDNPDEAQADITRRVENKEVVIGFGHPVYTTGDPRNQVIKEVAKKLSKDAGSMKMFDIAEALETVMWDIKKMFPNLDWFSAVSYHMMGVPTAMFTALFVIARTSGWAAHIIEQRIDNKIIRQSANYTGPENLKFVPLKDRK
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA.  Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower efficiency.
What are the official names of this protein?
2-methylcitrate synthase, 2-MCS, MCS, Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: ZFR_XENTR
Sequence: MIPICPVVSFTYVPSRLGEEAKMATGNYFGFTHGAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPAAHTATDYGYTQRQQEAPPPPPPVTTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATVAAAAQPQPAVAETYYQTAPIALSLPVAPKAGYSQGAAQYTQAQQTRQVTAIKPANPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTAVTYSGAAYSGYEAAVYSAASSYYQQQQQQQQKQAAAAAAAAATAAWTGTNFTKKPQFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTTSSSTAVRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQSVTSAAVSKPSTTSSSTSGANGSSSVGASPSVKLLTSSSSLSTSSSSKASSMSSTSIVKKVTTPKITFIGGNKLQSTGNKVDDSKMSDSAKTTPSTAAQTQEAKIDPMSEAAQTLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQHHWDDRRRVPEGGYPHGPPGPPGLLGVRPGMPPQPQGPSPLRRPDSSDDRYVMTKHAAIYPTEEELQAVQKIVSLTERALKLVSDSMADQDKSKTKESDDKKEPSKERALKGVLRVGVLAKGLLLRGDRNVSLVLLCAEKPTRALLSRITESLPKQLAVICPEKYEVSCSLAEAAIILNSCVEPKMQVTITLTSPVIREENLRDGDVTPGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWALELLVEKAISSSSGPQSPGDALRRVFECISSGIILKGGPGLLDPCEKDPYDTLATMNDQQREDITSSAQFALRLLAFRQIYKVLGMDPLSQMNQRFNVHNNRKRRRDSDGVDSFEAEGKKDKKDYDNF
What is the function of this protein?
Involved in postimplantation and gastrulation stages of development.  Binds to DNA and RNA (By similarity).
What are the official names of this protein?
Zinc finger RNA-binding protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MSRB_ECO27
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: VF196_IIV3
Sequence: MTNLSRGLLLLEDEDFTLVENQAKTFHLSHTVSGKYSIVMFYTDTCPQCSVLKPIVLYFVGDPLLQICLVNVYDSDSQNIIPMSLKSTTPLEYVPFIVFYVNGLPFKIFDGESTLLNFKNFILQTIQEADQIPTDTAAQQSEIPSYTLGKPKSSKVCYLTYEKAY
What are the official names of this protein?
Uncharacterized protein 020R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 196R family.
Protein: APOE_SAIBB
Sequence: MKVLWAAFLVAFLAGCQGKVEQVVEPELGPEPELHPQADWQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELTALMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLAQYRSEVQAMLGQSTDELRARLASHLRKLRKRLLRDVDDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRARAATVGSSLASQPLQERAQAWGERLRARMEEVGSRTRDRLDEVKEQVEEVRAKLEEQAQQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASATPVPSDNH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: IRAP_SALTY
Sequence: MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_METSB
Sequence: MSITPERKQTLVKEYAQKSGDTGSPEVQVAILTERIVNLTEHFKTHVKDNHSRRGLLKMVSQRRQLLDYVKNRDEPRYKSLIERLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HSCA_HAEIG
Sequence: MALLQIAEPGQAAAPHQHRLAVGIDLGTTNSLVASVRSGQSVILNDEQERSLVPSVVHYGVEEKKVGLEAFEQASLDPKNTVISVKRLIGRSLSDVQSRYSSLPYEFVASENGLPLIITAQGSKSPIEVSSDILSRLNHIAEQRLGGELSGVVITVPAYFDDAQRQSTKDAARLAGLNVLRLLNEPTAAALAYGLDSGQEGIIAVYDLGGGTFDISILRLSKGIFEVLATGGDTALGGDDFDHLIADWIIEQTKLKPQTANQQRELITLANQAKITLTNEKSAVISWQDFSVEISREQFNELIYPLVKRSLLTCRRALKDANVESEEVQAVVMVGGSTRVPYVREQVGEFFGKTPLTSIDPDKVVALGAAIQADILVGNKTDSDMLLLDVVPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMTVHVLQGERELVDDCRSLGRFTLRGIPPMAAGAAHIRVTYQVDADGLLSVTAMEKSTKVQSSIQIKPSYGLTDEEVTAMIKSSFDNAQEDLQARELAEQRVEADRVIESVIVALQADGAELLSTDEFHHIETVLKQLMDVKLGSDRDAIAQGIKALDTATQEFAARRMNASINKALTGKNLSDIENP
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CHS3_SOYBN
Sequence: MVSVEEIRNAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHMTELKEKFKRMCDKSMIKKRYMYLNEEILKENPSVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPLPVEKPLFQLVWTAQTILPDSEGAIDGHLGEVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPEKMEATRHVLSEYGNMSSACVLFILDQMRKKSIENGLGTTGEGLDWGVLFGFGPGLTVETVVLRSVTV
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 3, Naringenin-chalcone synthase 3.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RK176_ORYSJ
Sequence: MGNCWGAKISSESPCRSASSPSGGTSKYASNSSVSAASVPPTPRSEDEILEAANVKAFAFNELRTATRNFRPDSVLGEGGFGSVFKGWIDEKTLAPTKPGTGMVIAVKKLNQEGHQGHREWLAEVNYLGQLSHPYLVRLVGYCVEDEQRLLVYEFMPRGSLENHLFRRSTHFQPLSWNLRMKIALGAAKGLAFLHSDKVKVIYRDFKTSNVLLDANYDAKLSDFGLAKDGPTGDKSHVSTRVMGTYGYAAPEYLATGHLTTKSDVYSFGVVLLEMLSGRRALDKNRPTGEHNLVEWARPYLMSKRRIFRILDARLGGQYSLAKAQKAATLALQCISVEAKNRPNMEQVVAVLEQLQDSKETGANPQLQKKSSSKNAGSNGSKPSSKGKPANARLV
What is the function of this protein?
Functions downstream of CERK1 in the microbial peptidoglycans (PGNs) and fungal chitin signaling pathways that mediate innate immunity.  Participates in the activation of defense genes during response to PGN and chitin.
What are the official names of this protein?
Receptor-like cytoplasmic kinase 176, OsRLCK176.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RIMP_GLUDA
Sequence: MDADLPYLTGLDAKVAAIVAPVLADMGFELVRVAILGRESPTVQIMADRADGTLIAIEDCEQISHAVGAVLDVEDPLPGAWTLEVSSAGIDRPLTRAKDWTRFAGHLAKAEVNIPIDGRKRFSGILLGAEDGFGRLRLEDGTEVALPLSDMRRARLVLTDELIAASAHMMRAPGGAPEEGEEDTTEAAPEGAGKSPKPGRRPARKTH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAJ5_ECOLX
Sequence: MENDEKEHGRRRRQHLRVPVFPEEKDEIEANAKRAGVSVARYLRDVGQGYQIKGVMDYQHVRELVRVNGDLGRLGGLLKLWLTDDVRTLQFGEATILALLGRIEATQDEMSRIMKAVVQPRAEP
What is the function of this protein?
This protein is essential for positively regulating the expression of transfer genes that are involved in the conjugal transfer of DNA between bacterial cells.
What are the official names of this protein?
Protein TraJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_AZOC5
Sequence: MDKIRIIGGGSLNGTIPISGAKNAALPLMIAALLSEEKLVLENVPRLADVALLQRILGNHGVDITVNGKRNGDDPHAGQTMEIDARVIVDTTAPYDLVSRMRASFWVVGPLLARMGEARVSLPGGCAIGTRPVDFHLDALRALGADIDIDAGYVVARAPHGLTGARIVFPKVSVGATHTAIMAAALAKGDTVIENAAREPEIVDLADCLIKMGARIEGAGTSTIEISGVPRLRGARHSVLPDRIETGTYAMATAMTGGDVTLAGARADLLESALDVLRKAGAQIDVNNEGIRVRRNGAGIFPVEVSTAPHPGFPTDLQAQLMALMTRAQGRSRITETIFENRFMHVQELARLGANIHLEGDTAIVEGSDRLKGAPVMATDLRASVSLVIAGLAAEGETMIQRVYHLDRGFERLEEKLSRCGAQIERISG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAS1_CLOPE
Sequence: MSQHLVPEAKNGLSKFKNEVAAEMGVPFSDYNGDLSSKQCGSVGGEMVKRMVEQYEKGI
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein C1, ASSP, SASP, SSP-2.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.