PharMolix/UniProtQA huggingface dataset:
Protein: HS71L_HUMAN
Sequence: MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKELEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD
What is the function of this protein?
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes.  Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.  This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones.  The affinity for polypeptides is regulated by its nucleotide bound state.  In the ATP-bound form, it has a low affinity for substrate proteins.  However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins.  It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release (PubMed:26865365).  Positive regulator of PRKN translocation to damaged mitochondria (PubMed:24270810).
What are the official names of this protein?
Heat shock 70 kDa protein 1-like, Heat shock 70 kDa protein 1L, Heat shock 70 kDa protein 1-Hom, HSP70-Hom.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YH212_YEAST
Sequence: MSKTDVKKSREASGILTLQVNLRERRNFLNLMQNKLFSWKIRFSAIKGKCSQKSKYFRRSRSEDCYVEADLKILSRTRRSRKLPGTVPDFLGKQLIGISSSVVSRVSRSCR
What are the official names of this protein?
Putative uncharacterized protein YHR212C.
Protein: OADC_AZOVD
Sequence: MTIASQHDLRRQFRALLESNTCYDAASVFDPMSARIAGDLKFEVGILGGSVAALQVLAAPDYALITLSEFVEQATRIGRVACLPIIADADHGYGNAINAMRTVAELERAGVAALTLEDTLLPPKYGHKTTDLIPLDEAVGKIRAALEARIDPQLSIIARTNAEQLSVEETIGRAKAYQAAGADGICMIGIRDFEHLEAIAPHLDAPLMLITYGNPKLNDMARLAENGVRIVVNGHAAYFAAIKATYDRLREQRGVGPSDLSAKELCIKYSTLDEYRVFAREFMNVQE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
Protein: IBBA6_HYAOR
Sequence: WPPVEDRPCCERCTACTLMLPDEANTCVCGDIVPKCHQGCSLCERVDTPSGYQCKSFEYYNCGTKCP
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Strongly inhibits trypsin (Ki = 4 nM) and elastase (Ki = 4. 8 nM) (PubMed:33666645).  Also inhibits chymotrypsin with a Ki of 22 nM (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor A6, HOSPI-A6.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: STAD_CUCSA
Sequence: MALKFHPLTSQSPKLPSFRMPQLASLRSPKFVMASTLRSTSREVETLKKPFMPPREVHLQVTHSMPPQKMEIFKSLEDWAEENLLVHLKPVERCWQPQDFLPDSAFEGFHEQVRELRERAKELPDEYFVVLVGDMITEEALPTYQTMLNTLDGVRDETGASPTPWAIWTRAWTAEENRHGDLLNKYLYLSGRVDMRQVEKTIQYLIGSGMDPRTENNPYLGFIYTSFQERATFISHGNTARLAKEHGDIKLAQICGTITADEKRHETAYTKIVEKLFEIDPEGTVIAFEEMMRKKVSMPAHLMYDGRDDNLFHHFSAVAQRLGVYTAKDYADILEFLVGRWKVESLTGLSGEGQKAQDYVCALPARIRKLEERAQGRAKEGPTIPFSWIFDRQVKL
What is the function of this protein?
Introduces a cis double bond in the acyl chain of an acyl-[acyl-carrier protein].
What are the official names of this protein?
Acyl-[acyl-carrier-protein] desaturase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=In green tissue, found in chloroplasts. In non-photosynthetic tissue, found in plastids.
Protein: PYRB_ANADF
Sequence: MIGRHKHCISLAEYSREEILEVLDLAVSMKEVLQRPIKKVPSLRGKSVVNLFFEASTRTRSSFEIAAKVLSADALNWTASASSVTKGETLVDTARNLEAMRPDVLVIRHSAGGAPRLVAEHVGCSVVSAGDGAHEHPSQGLLDCFTLREKLGTLEGKTIAIVGDISHSRVARSDLHAMTKLGARVRLCGPPTMIPAGIEALGATVRTQLREAVEGADAVVMLRIQHERIGDPLIPGTREYSKLWGLNAKKAAEWLRPECVILHPGPINRGVELSPEVADGPQSVILDQVQNGVAVRMAILYLLAGGNPADAGEAKA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: DPH1_CANGA
Sequence: MDNTTEKKEPTKVPRRRFVGKRKTDGKTITTVKADGNEVVRQTKSRVHVGRSLNHIPDDIMEDEELNEAIKLLPQNYNFEIHKTVWNIRKHGAKRVALQMPEGLLIYSLLISDILEQFCNVETVVMGDVSYGACCIDDFTARALDCDFIVHYAHSCLVPIDITEIKVLYVFVTIAIDETHVIKTLQKNFPKGSRLATFGTIQFNPTVHSIKDTLLNDKEHMLYIVTPQIKPLSRGEVLGCTSERLDKNQFDAMVFIGDGRFHLESSMIHNPEIPAFKYDPYNRKFTRERYDQKQLVQVRGEALQVAQKGKVFGLILGALGRQGNVDTVRNLEEKLIKAGKTVVKIILSEIFPQKLAKFDKIDVFVQVACPRLSIDWGYAFPKPLLTPYEANVLLNHDVMFSEEYYPMDYYETNGYGRGRIPEHALVKN
What is the function of this protein?
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_DESVH
Sequence: MAELVVALDFPAADVAVDMAGRLRGTAPWMKVGLELFCAAGPDVVRAVADLGFRVFLDLKFHDIPNTVRGAVRSAVRSGADMVNIHLMGGERMARAAVEGLHEGAQTTGSVPLLFGVTVLTSTAQGELPGISTDIGEYAASLAASGAAWGLNGVVCSGYEVESIKKRCGASFLCLTPGIRPGGGAGGDDQRRVMTPAQAVSAGSDYLVVGRPVTGAADPAAAARAIMAEMAAVRR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: UREF_UREU1
Sequence: MMLNSDYLNLLDLMQITNANFPIGTFSHSFGIETYIRKDIVFDGDSLIRALLLYMNEQLLHGDLLAIYQIFKLLPKQKINAIWEIDQMINFQGLARETREGQRRIGQQMVKIYNELFDCELLVEYAQRIKDRKSYGNPAVAFALLAMHLKIDLKTALYTHLYSTVAALTQNCVRAIPLGQVKGQKIIHKLKHVYFDDIIDKVFSLDFKTDFCKNIPGLEIAQMEHEDTPVRLFMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATBP_DROGR
Sequence: MGFPRILSKNHKIYTKLGEFCLSGDSFWIVCHTCQEELQTQDAFWKHIQDEHNFLHGVAKQEHNRSSSSSYCLADVESASAVTSNTTSVQTAGNVTTVAVPVALYKYTEDEQRDVAAAVELHEAQHQQQQQQQQHQQQQQQQQHQQQQQHQHHQHQQQQQHLHQQQQQQQQQQRDAAKELAELHAVAAAAAAAGGGGGDSSAHSSSIGGGIDIKVELTPEMQVAAAAAAAASSNTTIYHLSQVVPVSAPAPPPPPPTAAAASSFLSGGAGSATAATIVGVSTTATTTAAAAAAVTTVPQQSQLGSGNNAGAVMQQLGLPLIAVAQELAPKDSNSTTASASSAVSSDDGERWYVCDYGTCGIKFKYKSRMELHRVVHSKERRFNCDMCSASFKQSCNLSTHRKKKHSLRGIKSDLLPQRF
What is the function of this protein?
May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions.  Binds to AT rich DNA (By similarity).
What are the official names of this protein?
AT-rich binding protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL4_BART1
Sequence: MDLVIKTLDGHEAGKLKVSESIFDLVPREDILQRVVRWQLARRQQGTHQSQGRSDVSRTGAKMFKQKGTGRARHSSARAPQFRGGGKAHGPVFRSHAHDLPKKIRALGLRLALSAKLKAKDLIVVDELAVKDAKTKKLVSHFSKLGFNNALLIGGQEIDINFFRAASNIPNIDVLPIQGINVYDILRRSKLVLSKAAVEALEERFR
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NUD19_MUSSA
Sequence: MSGQSSWRRAATVMLAAGWTHSSPAGFRLLLLQRAQNQRFLPGAHVFPGGVLDAADSSPDWVRLFAPRHTPPRFGLGPEPPRQPPFPGLSHGDADPAALPDDVALRICAIRETFEEAGVLLLRPRDAPASQEPSQALSPPAGLAEWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGRSLRRFDTTFLLCCLRDTPRVEPDLAEVVGYQWLSPSEATECFLSKEIWLAPPQFYEMRRLENFASLSALYRFCSDRPLEVAQKWLPIILVTSDGSVHLLPGDELYVKDSDFLEKNMSTDKKTEEIMKEGKVLNRIVIRSPYVYEIYVTLPSENKHVFPRNYIVNKSRTARL
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).  Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase NUDT19, Androgen-regulated protein RP2, Nucleoside diphosphate-linked moiety X motif 19, Nudix motif 19, Testosterone-regulated RP2 protein, RP2p.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PB2_I72A4
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTLIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: TF4_TERSU
Sequence: MTKLTVLLLAILVLLPLATSNSAADEALASLSGLLRRAKRCVPQNSCTSNADCCGSYTCSCVSQPSCKGMNPRRRCM
What are the official names of this protein?
Teretoxin Tsu15.4.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_MYCGI
Sequence: MSELIKLDAATLADKISSKEVSSAEVTQAFLDQIAATDGDYHAFLHVGAEQALAAAQTVDRAVAAGEHLPSPLAGVPLALKDVFTTTDMPTTCGSKVLEGWTSPYDATVTAKLRSAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWDTERVPGGSGGGSAAALAAFQAPLAIGTDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPLDSTSVEAPVPDVVAAARTGAGGDLTGVRIGVVKQLRSGEGYQAGVLASFNAAVDQLTALGAEVTEVDCPHFDYSLPAYYLILPSEVSSNLAKFDGMRYGLRAGDDGTHSAEEVMALTRAAGFGPEVKRRIMIGAYALSAGYYDAYYNQAQKVRTLIARDLDAAYQKVDVLVSPATPTTAFRLGEKVDDPLSMYLFDLCTLPLNLAGHCGMSVPSGLSADDNLPVGLQIMAPALADDRLYRVGAAYEAARGPLPTAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: THN24_ARATH
Sequence: MEGKTLIVSVLIMSLFMAQNQVDANICCPSIQARTFYNACLFAVGSPSSCIRNSSCLDISESTCPRGYTNDILENTGDAVTEYCKLGCVSSVCGALTILQNSDASEIVNGEVEKCTMACSTVCTKGSMNAVENA
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Probable thionin-2.4.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HOFM_ECOLI
Sequence: MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDIIKDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWLSGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPDASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPESVAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY
What is the function of this protein?
Required for the use of extracellular DNA as a nutrient.
What are the official names of this protein?
DNA utilization protein HofM.
Protein: SYC_BRUA4
Sequence: MAYAPQLRLYNTLTRMKEEFSPLDADNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAEHVTYARNITDVDDKINARAARDYPDLAFNEAIRRVTESTNAQFQADVTALGNLQPSVQPRATEHMDEMRAMIDRLVKLGVAYVAEDHVLFSPSAMNERKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKEGEPGWSSPAGIAVLGRPGWHIECSAMSMAKLLEPFGGGLKCDDPLKNQFDIHGGGIDLVFPHHENEIAQSCCAFGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNEGLPQLGVWDDVDARDRWIGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDRKFTVPETLTAVGEVVEALSDDLNSWTAITALRKAFKARDITGLGEGMALLGLLDPHFVMAEDIPVFAKAEVDHQAIEARIAERLRFINEKNWAEADRIRDELLQEGVQLKDGKDPATGERTTSWDVVG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_BORPA
Sequence: MSNRERPVKPYDLTVSVTPRYVPEQSDPSQQQYVFAYTVRITNTGSHPAQVISRHWIITDGEERVQEVRGLGVVGQQPLLAPGETFEYTSGCPLPTPIGTMRGTYHCVGENGIPFEVPIAEFLLAMPRTLH
What are the official names of this protein?
Protein ApaG.
Protein: LPXD_PSEA8
Sequence: MMSTLSYTLGQLAAHVGAEVRGDADLPIQGLATLQEAGPAQLSFLANPQYRKYLPESRAGAVLLTAADADGFAGTALVVANPYLAYASLSHLFDRKPKAAAGIHPTAIVAADAEVDPSASVGAYAVIESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTIGARVSIQSGAVIGGEGFGFANEKGVWQKIAQIGGVTIGDDVEIGANTTIDRGALSDTLIGNGVKLDNQIMIAHNVQIGDHTAMAACVGISGSAKIGRHCMLAGGVGLVGHIEICDNVFVTGMTMVTRSITEPGSYSSGTAMQPAAEWKKSAARIRQLDDMARRLQQLEKRLAAVTSSGDASSDA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: BIOF_ACIF2
Sequence: MHSEREESWRAELSALRAHDLWRELQVLQPAPERGPPTFVGTRGEPLLSFASNDYLGLSAESALRDAAIAEIQQSGVGAGAAPLLGGERPAHAVLANALARWLGVEAALLFGSGYLANLGVISTLVGRGDRVYADRLNHASLVDGVRLSGARLHRYRHGDMTHLAQWLERGGRGQAWIITDGVFSMDGDIAPLPELATLAQQYGAGIILDEAHAFGVLGTEGQGTAAHWNMDIHGVDVIMGTLGKAFGVYGAFVAGSQDVVDLLRNRARSFIYHTALPSALAAAALVALDLLRHGDARRERLTQHRQHLRAQVPDAPWLASETPIQGLLLGDARRALTVSAQLRRAGLYCPAVRPPTVPADSARLRITLSAAHSHDDIELLATTLREVL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ARLY_CALBD
Sequence: MSNLKLWEGRFSKSTAQIFDLFNASIMTDIKLFEYDILGSVAHVKMLAKCNIIREDEAKLIIDSLYQILEDFKLGKIVFGISDEDVHMLIEKELIKRIGEVGKKVHTARSRNDQVALDERLFCREKNLYLQELIKTLINTITTLAEENIDVIMPGFTHLQKAQPILFSHYILAYAQMLKRDLLRLRHNYSMTNSSPLGSAALAGTTFEIDRFFVASELGFESVTENSVDTVSDRDFILEMLFSLAMIQMHLSRLAEDFIIFNTDEFKFIELDDSFCSGSSIMPQKKNPDALELIRGKTGRVYADLIGLLTVLKGLPLSYNKDLQEDKEFLFDSIETVEMSLIVINEILKTLKIDKENMVNSCKSGFINATDLADYLVTKGVPFRDAHFIVGNIVKYCIESDKTLEDLSLEEYKRFCEKIQEDVYQFIKIETCVNRRKSYGGTSLESVRKQIDNLKEFLNKLK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP6R2_MOUSE
Sequence: MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVNLITQDPPQDMEEKVRFKYPNTACELLTCDVPQISDRLGEDESLLNLLYDFLDQEPPLNPLLASFFSKTIGNLIARKTEQVIMFLKKKEKFISQLLKHIGTSALMDLLLRLVSCVEPVGLRQEVLHWLNEEKIIQRLVALIHPHQDEDRQSNASQALCDIIRLGRDQGSQLQETVEPDPLLITLESQDCVEQLLKNMFDGDQTESCLVSGMQVLLALLEPRRVGTEGLVDSFSQGLERSHSVSSSILRGIEPWLKNFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGARLMAALLHTNTPGINQELCRLNTMDLLLDLFFKYTWNNFLHLQVELCIAAILSHAAREEQAEASGSDGKVEPLQGSGDGNGKLETTPSITSPPENTMVTHLFQKCCLVQRILEAWEANDHTQAAGGMRRGNMGHLTRIANAVVQNLEQGPVQAHISEVIRGLPADCRGRWESFVEETLMETNRRNTVDLAFSEYQIQQMTANFVDQFGFNDEEFADQDDNINAPFDRIAEINFNIEADEDSPSAALFEACCSDRIQPFDDDEEEDIWEDDETRCAARVMARARFGAPHVSDNYSKNALEHGGQDRKTGSAVARNVPGLAAPSSPTQKEGPRSESDSAGTTWTAVFDEPVNPLSATPGAARDVGSSAWAAGPSVVEEKGWAKFTDFQPFCCSETGPRCSSPVDMDHSNAEGGQSPGPEKTFGPTSPCAWNVCVTRKAPLVASDSSSSGGSDSEDDEKAAGAVEAVCTGHTGKVSPPPRTAEAAVGRAECPDSTVLAPACPAPSEVTISPAVATIAPSKAGSPTATIVVSSSVAAAVPPGPIVAVTTAAPAIVATLGTMTKDRKADALPEGAALNGPV
What is the function of this protein?
Regulatory subunit of protein phosphatase 6 (PP6).  May function as a scaffolding PP6 subunit.  Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory subunit 2, SAPS domain family member 2.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_THEVB
Sequence: MTTAVILGLLALISYLLGSIPTGYLLAKALRGIDIREHGSGSTGATNVLRVVGKGPGLVTFLVDVGKGLGAILVARWVLGQAWSPVPAGWFEFVLLAIAFIAVLAHSKPIWLGWRGGKSVATGLGVLLALNAPTALATFGVFLVVLAVSRIVSLSSMTAAIALPFWFWFFTQSWPFVGFSVIAGAFVIWRHQSNIQRLLAGTEPRLGASQG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURA2_ALKCK
Sequence: MQKLLIEGGHTLEGTVSISGAKNSAVALIPAAILADSAVVIDNLPVISDVDLLAELLREIGGDVDLGNQTMTIHPEKMVAMPLPNGRVKKLRASYYLMGAMLGKFKKAVIGLPGGCNLGPRPIDQHIKGFEALGAQVTNEQGAIYLRANELRGAKIYLDVVSVGATINIMLAAVRAKGRTIIENAAKEPEIIDVATLLTSMGAKIKGAGTNVIRIDGVDHLQGCRHSIIPDRIEAGTYMIMAAAMGRRVHIDNVIPTHLESVTAKLREMGTTVEEYDDQLIISGMDPKKGVDIKTLVYPGFPTDLQQPFTSLLTSAEGTSIVTDTIYDARFKHVDELRRMGASVKVEGRSSIVNGKSSLQGAKVKASDLRAGAALVIAGLMAEGITEVSGLEHIDRGYEHLETKLTRLGAKVWREELTEEELEQVKQS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_LISMO
Sequence: MTSEQFEYHLTGKEILEKEFKTGLRGYSPEDVDEFLDMVIKDYSTFTQEIEALQAENIRLVQELDNAPLRTSTQPAPTFQAAAQPAGTTNFDILKRLSNLEKHVFGNKLDDNE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: CYSD1_MARN8
Sequence: MTLTPPKKTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLAMKAFAPGKPPFPLMHVDTTWKFREMITFRDQMAEKLGMKLLVHTNQEGVEQGIGPFTHGSAKHTDVMKTQALKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKFHRWDPKNQRPELWNLYNGKVNKGESIRVFPLSNWTELDIWQYIYLENIDIVPLYYAAERPVVERDGTLIMVDDDRMPLEPGEQPMMKMVRFRTLGCYPLTGAVESEAATLPDIIQEMLLTTTSERQGRVIDHDGAASMEQKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2 1, ATP-sulfurylase small subunit 1, Sulfate adenylate transferase 1, SAT 1.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.