PharMolix/UniProtQA huggingface dataset:
Protein: LTXA_AGGAC
Sequence: MATTTLPNTKQQAAQFANSVADRAKENIDAAKEQLQKALDKLGKTGKKLTLYIPKNYKKGNGLTALIKAAQKLGIEVYHEGKDGPALTNGILNTGKKLLGLTERGLTLFAPELDKWIQGNKHLSNSVGSTGNLTKAIDKVQSVLGTLQAFLNTAFSGMDLDALIKARQNGKNVTDVQLAKASLNLINELIGTISSITNNVDTFSKQLNKLGEALGQVKHFGSFGDKLKNLPKLGNLGKGLGALSGVLSAISAALLLANKDADTATKAAAAAELTNKVLGNIGKAITQYLIAQRAAAGLSTTGPVAGLIASVVSLAISPLSFLGIAKQFDRARMLEEYSKRFKKFGYNGDSLLGQFYKNTGIADAAITTINTVLSAIAAGVGAASAGSLVGAPIGLLVSAITSLISGILDASKQAVFEHIANQLADKIKAWENKYGKNYFENGYDARHSAFLEDSLKLFNELREKYKTENILSITQQGWDQRIGELAGITRNGDRIQSGKAYVDYLKKGEELAKHSDKFTKQILDPIKGNIDLSGIKGSTTLTFLNPLLTAGKEERKTRQSGKYEFITELKVKGRTDWKVKGVPNSNGVYDFSNLIQHAVTRDNKVLEARLIANLGAKDDYVFVGSGSTIVNAGDGYDVVDYSKGRTGALTIDGRNATKAGQYKVERDLSGTQVLQETVSKQETKRGKVTDLLEYRNYKLDYYYTNKGFKAHDELNSVEEIIGSTLRDKFYGSKFNDVFHGHDGDDLIYGYDGDDRLYGDNGNDEIHGGQGNDKLYGGAGNDRLFGEYGNNYLDGGEGDDHLEGGNGSDILRGGSGNDKLFGNQGDDLLDGGEGDDQLAGGEGNDIYVYRKEYGHHTITEHSGDKDKLSLANINLKDVSFERNGNDLLLKTNNRTAVTFKGWFSKPNSSAGLDEYQRKLLEYAPEKDRARLKRQFELQRGKVDKSLNNKVEEIIGKDGERITSQDIDNLFDKSGNKKTISPQELAGLIKNKGKSSSLMSSSRSSSMLTQKSGLSNDISRIISATSGFGSSGKALSASPLQTNNNFNSYANSLATTA
What is the function of this protein?
Virulence factor that plays an important role in immune evasion.  Lyses human lymphocytes and monocytes.  Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts.  Shows also beta-hemolytic activity on certain types of growth media.
What are the official names of this protein?
Leukotoxin, Lkt.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein; Extracellular side. Secreted. Note=Leukotoxin expressed by the rough, adherent, clinical isolate CU1000N is cell associated. However, smooth, nonadherent strains, including Y4, JP2 and CU1060N, secrete an abundance of leukotoxin into the culture supernatants during early stages of growth (PubMed:11035711). Secretion is inhibited by free iron (PubMed:17041062).
Protein: PRS7_RAT
Sequence: MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIPVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with TRIM5 in cytoplasmic bodies.
Protein: KAPS_PENCH
Sequence: MSTNITFHASALTRSERTELRNQRGLTIWLTGLSASGKSTLAVELEHQLVRDRRVHAYRLDGDNIRFGLNKDLGFSEADRNENIRRIAEVAKLFADSNSIAITSFISPYRKDRDTARQLHEVATPGEETGLPFVEVYVDVPVEVAEQRDPKGLYKKAREGVIKEFTGISAPYEAPANPEVHVKNYELPVQDAVKQIIDYLDTKGYLPAKKE
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase, APS kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ATPG_NOCFA
Sequence: MASLRELRSRIRGVNSIKKITKAQELIATSRISKAQARVAAAKPYAEEITKVLGELASASKNLSHPLLTERPNPRRAAVLVITSDSGMCGGYNSNVLKRAEELMTTLRNEGKEPVLYVMGAKGLTYYTFRNRPFVSAWTGFSQQPKYTDASAACRHLVDAFMVGSDGEVPHPNGTGDIAGVDELHIVYTRFVSMLTQTPEVRRLAPIQVSFVDENFDMGEDSFSDSPTAEVQAQYEFEPDADVLLAALLPKYVNTRIYASLLEAAASESAARRTAMKAATDNANELASVLQREANSVRQAQITQEISEIVGGVNALASSSDRD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y068_SIFVH
Sequence: MFAELYIMSVESKHYASGTIYTPDGIQQFNGIFDDFDDVFNIKPTFATRIHCSHDEYCIDNGKTSFYYLTYKDIEDLKRMLTFMSGDSSAYLVYVPSDVIKELGINHSSSEITFSDVSIPRLEYIPCKFLGNIPTYIKLIGNTVYVNGVNVNMTVSDPDQLKELVNEIFRIYIIKYYKGLLTWSLILKMWCGIKIS
What are the official names of this protein?
Uncharacterized protein 68.
Protein: SLAB_ACIAM
Sequence: MVKYMNLIVLGMLMFGVFVTLSLGSSTALTVYSPFPGEHVALINPKELILNISVYDPIAPVNSTVGVTISGPYDIKMTSAGVPVGELNSSHMLTVTDYAFPVTLFEANGTQISAFIPGQYNVTISVAGCSETIPIYVISPNEIEILVCVYSNGVPLPGATVSIYNVTNGELLLTNTTNSQGLAELTVPYVYTMTNEYNVTAVKPGYQLVYKEVTVPADHITPVTVKLTTKPITFVLTPVYFQDMGVIEPAEPAQLPGTPEPVYVASAYMGTTFSIIINATESGMPVQGATISASYLISGKQMSSTATYIGNGQYNLSIVLPNSTVPYDLELVITGTYQTNTYTFITLLSVQPNFYCEIQRLQSEVSVLESEVDQLKVEIQSLNETLTLQASEIASLKTYLEGNVSYFSMQISSLESEIKYLNSTLMTLSSELTTVNSTLTSEVNSLTSEVNSLSTQVSTLSTEVNNLNTTINNDNQKISSLTTLVYGGIILGVIALIIAIVAVVLVFRKVA
What is the function of this protein?
S-layer small protein.  May anchor the complex to the cell membrane.
What are the official names of this protein?
S-layer protein B, Surface layer small protein.
What is the protein family that this protein belongs to?
Belongs to the Sulfolobales SlaB family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Cell membrane; Single-pass membrane protein.
Protein: PROA_ECO24
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLGEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGSVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_SHEPC
Sequence: MSTNHIQPLLDLLYQGKSLSREQAFEIFSALIRGEMSEATMAGMLVALKMRGETIDEISGAADAMRAAAKTFPYSNGDSLGNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPDTASRCLDALNLCFLFAPHYHGGVKHAGPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALHGNTQVAELKDGDIIEYQLTPADLGVPLAQISELEGGEPAQNALITEAILRGRGTDAHANAVAINAGCALYVCGIADSVKTGTLLALSTIQSGKAFELLSQLAKVSSETKE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ARFG3_HUMAN
Sequence: MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSLASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1).  Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein 3, ARF GAP 3.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Protein: SUCC_SALTO
Sequence: MDLYEYQGRDLFERHGLPVLAGGVATTPEEARAIAERLGGRVVVKAQVKVGGRGKAGGVKLTEGAEETVARATDILGMDIKGHTVHKVMITVTADVAEEYYFSYLLDRANRTFLCIASVAGGMDIEQVAAETPEKVVKEPIDANTGVDVATARRIVTQAGFPAEVADQTVEIAVDLWKAFVAEDATLVEVNPLAKTAEGGLLLLDAKVSLDENAAFRHPDHEALVDQAAVDPLEQAAKEKDLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGERHGGVKPANFLDIGGGASAAVMANGLEIVLSDPAVKSVFVNVFGGITACDAVANGIVQALALLEQRGEKVTRPLVVRLDGNNAEAGRAILDGANNPLIQRVDTMDGAAERAAELAAAGV
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RUVA_XANOM
Sequence: MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTGIGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAISEATVALQQLGYKPAEAARMARDAGAEGGEVATVIRKALQAALR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DXR_BORPD
Sequence: MSRFQRVAVLGSTGSIGESTLDVIARHPEQLAVFALSAHSRIERLAEQAAASAAAVVVVPDAAARQRFLAAWPAGRTPPEIRVGAQALADTAADAACDTVMAAIVGAAGLPAALAAAQAGKRVLLANKEALVAAGALFMRAVRANGAELLPIDSEHNAIFQCLPHEGRASAPEQPARGVRRLILTASGGPFRRHDPLDLHEVTPDQACAHPNWSMGRKISVDSATMLNKGLEVIEAHWLFAMPPERIEVLIHPQSVVHSMVEYDDGSVLAQLGQPDMRTPISYGLGFPERLASGVGPLDLARWGRLEFETPDLRRFPCLQLAFDALRAGQAACVALNAANEVAVDAFLSGRLRYTWISRVIAAALEWQQRQSSVTLDSLADVLALDAATRAYAGNLGLA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: EFR3_COCIM
Sequence: MNSVRQSCRPKHQVLILKCYPRFQKGVQSVKPNSSELSYLLYYASTRRSKLQKVGAFLEKRAARDVWRGKLGNVQVTLQILAALIEKVPRDLPLYARSILTVLDIVLRSREISMVEETIPTFELFCRHQDSATLTADHEYIIQYRELVGTYASFASTETPVTTKTPMSAPMALRWRTVGLKAIKSIVTSEILSTDGAKQLNVVIPVILQNLYASGDHRLSPLQEKAKSSERLEREQFRRRRMSISTVQTVDTIDGNGDPESASGSAADADMMAEMEARVLALRCLEKVFSGTNRVQIRFATSLVLSFIVSRRPPRTQEKQRSANGKTDGNWATNLLEVIANWSPVQDRFIILVTLLETLVERPLVDGQLEPQLTLASMMDWLLGSSVNLIGLSVMDVLIGLLQFVRQLLQLGNGTQTLVPHHGLSTLIKPLPQMDETAATNSQTNGENEKAPTADSLRHELLELLENCIGNLATHVYYGDQVSDMIRTIVIRIKPSPALEGENAHHESESDNAIQKSSPSRSDYTAESYFSSSAARITALRSVKDILVVANLRKSTSGTDPDARNRVPLHVWEGTHWLLQDPQWEVRNAYVDAFLSWLQLETKKSDLRVPTEHTRVSKMGNRRDTSDIPERLARRIVSTAPQEENVAACHASSFLQLLHLTIFDVVSESSTTESDILRLYLLLVNLVEHLGVNAARYTLPVLMKLQDTLPSSVSASKALHIGSLVHGYLLALVEKFDLEGTRPAAEIINEISKRKKRGVWLDKIQLPPRPLHHIQPSLDTVIEQASLPQPDKNIYSRFTSLEELVRQIESTYNSSYVSPPISPSNSPGRSFSIPSLGLNNSTNPHVPAGSQLPLHVKEHMLAPWSKEACLDAIEKEKAKTSSLSGSRTATGAFAAGLNALNMSAYNSGPGSPTGTAPSASNRQDRPVSAAYAPTGNLAGFQKTRRQSIPERRVSPAASSRDSTVRVNELRRVLSVINSSNVRHPSPLRGRHRVDSTVSSTESMVSDNLSFSDAGTAAADRPLSSRENLTAPRGLNRYHGGPNQLHGDFEPEYIPPVPPLPSSLAIPGGFPADSRSGSSVTSPSHSPPRSDRPSTAPGRPARTHSKSKGSNASTLRQSRSLSRKKSLDTSLHERSERRATDLNGIPSGHSHGYSEDLGDIGIAITADTTEIAPHTQDRADTSSQWSRREASRTLSFGRRVDMDKLLEGLSAPNDDQQPNGTGEVSGIKIASSGVEGSSSLTRMGKKPSFQSMNDEKKASYSRKTSLLSPGAAPWNRLSSDRGGIGPPPY
What are the official names of this protein?
Protein EFR3.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
Protein: YRHH_BACSU
Sequence: MLENRLYKRSDFWKLFSRKYKLTKTIEHMMIDSIDIQENDRILEIGIGNGTVFKSITKKLKKGSLKSIDPSKRKVRQISRANRKNMGNGEVFHGYPEDIPFDDRTFNKVFSLHTVQSCTDIRLALREIYRVLQIDGRFYISIDTNTGEKEKTYIQLLKDQHFRDLSVIRRASCLCIVAVK
What are the official names of this protein?
Putative methyltransferase YrhH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MTEF5_DROME
Sequence: MLRNGQNQAQLLARSLGQLARGMASSKRVSSKKEDLKPKLPKPPTVEIPMEEPLNASYLSKTLGSSYRSWAAALEKHPELKTLKRKDLLSSYDTLKSLDYSVDDIIAKPMIIYYGATTLANRHSVLQECGFHNVTVQTLAKYVTVVNKPIEVLKAHNYIPFDVKVAERLAGYFKDIKLPVDLRELESETLTLKSLRQSLINAYLRERLQMDDNDLQKLWRVYTRIRHKSFRAVQDTIELLTKEFNFSAERLRKNSFLLYSEADNVRRILREVPTIDSQDIREIGFRRPKILMSTCDSLKQTLQHVHAFGISEDAVLRCLEVLTLGPDTVLERLRDLQEIEEFQVLGTNPRILRLVHYQNKARLRLDYLNQLRVRCASLHILSCGSEAFAKFARDGSDRTKGRDIVVYLSNVLGKDVQVLRNLLSRHPNWCHIPLLHVKQCLEYLRSKKFKLNEIFANIHLLLYPIKRIEEKMLLLQSPDAQEDLQLPVANFDSLSNNEILTLILYLIESEFHFTGDGIWTEQHTHHVENFNNLLPDFPESLNKVYKYGVKPAEKMIMERL
What is the function of this protein?
Binds promoter DNA and regulates initiation of transcription (PubMed:22784680, PubMed:24068965).  Regulates mitochondrial replication and transcription (PubMed:22784680, PubMed:24068965).  Required for normal topology and maintenance of mitochondrial DNA (mtDNA) levels (PubMed:22784680, PubMed:24068965).  Regulates mtDNA replication by re-activating replication after replication pausing (PubMed:24068965).  Likely to regulate replication pausing by coordinating with the mitochondrial termination factor mTTF which promotes replication pausing (PubMed:24068965).  Their function in replication pausing prevents unregulated replication that may occur for example by collisions between the machineries of DNA replication and transcription during mtDNA synthesis (PubMed:24068965).  This ensures the incorporation of RNA transcripts into replication intermediates at the replication fork and allows for proper fork progression (PubMed:24068965).  Possibly functions downstream of Dref which activates genes involved in mtDNA replication and maintenance (PubMed:24068965).
What are the official names of this protein?
Transcription termination factor 5, mitochondrial, Mitochondrial transcription termination factor 5, mTerf5.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KIRO_ACTDE
Sequence: MDLSGKMVKQVEILSDGIVFYEIFRYRLYLISEMSPVNIQGVDLLEGNWGTVGSVIFFKYTIDGKEKTAKDIVEAIDEETKSVTFKIVEGDLMELYKTFIIIVQVDTKGEHNSVTWTFHYEKLKEDVEEPNTLMNFCIEITKDIETYHLK
What are the official names of this protein?
Kirola.
What is the protein family that this protein belongs to?
Belongs to the MLP family.
Protein: WAKLM_ARATH
Sequence: MSYKNTNNSHLILFKLLLLLILYSADLTASSSCRSECGGCKCGGIAIPYPFGIGKGCYLEKSYEIECLNTSGKLVPFLSVISKEVVSIHLPGRQSFGSVRVRSPITSAGCSSDGKDSAPVMNLTDSPFFVSDINNLVGVGCSSKVSLEHIKQNMVGCELNCSTTNASDSNSIPFFDKTGCSFSYTFAQVCTGNKPEDMGCDGRGCCQASLPREPQQVIGIRIESNDGKSTTSGDCRVAFLTDEFFSLSKLTKPEQLHAKRYATLSLGWIMQTRNTSFVNSLACKIRKDTDTAYSNDQSIKCICDYTMSIISDIRYANCECNLGYKGNPYDSDGCRDIDECKENPKYCKETDTCVNFEGGYRCVGDKTKAIMIGAGTGFGVLVLVGGVWWLRKFLVKRRMAKRKKKFFKRNGGLLLQQELNTRQGVVEKARIFTSKELEKATENFSENRVLGHGGQGTVYKGMLVDGRTVAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCCLETEVPILVYEFIINGNLFKHIHEEEADDYTMIWGMRLRIAVDIAGALSYLHSAASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYRSSQYTEKSDVYSFGVILAELITGDKPVIMVQNTQEIIALAEHFRVAMKERRLSDIMDARIRDDSKPEQVMAVANLAMKCLSSRGRNRPNMREVFTELERICTSPEDSQVQNRIDEEEEEDGVEEEEEVVTIVHRGDSWSIGVTAPASSIVASPPSSDVEPLNPLLTW
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GBUA_PSEAE
Sequence: MDKNLHQPLGGNEMPRFGGIATMMRLPHVQSPAELDALDAAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVVRR
What is the function of this protein?
Catalyzes specifically the hydrolysis of 4-guanidinobutanoate to 4-aminobutanoate and urea.  Has no activity against arginine, agmatine, 3-guanidinopropionate and guanidinoacetate.
What are the official names of this protein?
Guanidinobutyrase.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: RS16_HAHCH
Sequence: MVTIRLARGGSKKRPFYHLNVTDSRNARDGRFIERVGFFNPTARGNDERIRVDAERLQFWVERGAQMSDRVRDLVKASA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MIFM_BACSU
Sequence: MTMFVESINDVLFLVDFFTIILPALTAIGIAFLLRECRAGEQWKSKRTDEHQTVFHINRTDFLIIIYHRITTWIRKVFRMNSPVNDEEDAGSLLL
What is the function of this protein?
Sensor protein that up-regulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited.  Acts as a ribosome-nascent chain complex.  When the primary membrane protein insertase activity or level is reduced, the membrane insertion of MifM is impaired, which induces arrest of MifM translation and unfolding of the mRNA hairpin.  Unfolding leads to translation of the downstream gene, which encodes the secondary membrane protein insertase MisCB/YqjG.  Translation arrest of MifM is mediated by interaction of its C-terminal domain with the ribosomal polypeptide exit tunnel.  Undergoes multisite stalling, which may allow a sufficient duration of ribosomal stalling and consequently sufficient levels of MisCB/YqjG.
What are the official names of this protein?
Membrane protein insertion and folding monitor, Sensor of SpoIIIJ activity.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AROD_METM7
Sequence: MICIPVIDENVCDAINSAKEALKYGDIVEFRVDLLKDVTFEDIEEFSKVPSIITIRAEWEGGNWKKSDNERIELLKHAIKNNAKFVDIELKEERNLELVKYRNESNSNTKIIISYHDFEKTPEIDELIEVVEKELKIGDIAKFATFAHSKEDTLKILNLMNKYAGKIIAIGMGESGKLTRILGLDFGSILTFASMEGKASAPGQVDVKKLKEILKLIG
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: NPS6_COCH4
Sequence: MARHQAVSQLHFFALILESLFKGADHPLSHFHNVSEDELDELWSWNTPLQPELRFCMHEKVSERAALHPEKIAIDAWDGTLTYGQIEDYSDKLAKLLRLLDDSSNRIIPVLFEKSRWTSVAVLAIMKSGACFALLDPAQPEGRLRAVVQQVNAKIFLSSKAQSTLAARVAPAATIIPISKSKFNKIFSPYTAEQPNTTLPPVSPDQPLYIQFTSGSTGVPKGCILTHSQYTSGAIPRAAAVGYYPHSRVLDFASYAFDVCIDSMLCTLAHGATLCTPSDERRMNDMSGAMRDMQVTFAGMTPSVARTLEVDILNNLESIALGGEGVSISDAMSWGQRTRVVNAYGPSEATVGATINDNVAAKPYITMGKRKGCALWLSDPENHNKLVPVGAVGELLIEGPIVGNGYLNNPSKTKEVFIEDPEFLLKGSKSYPGRHGRIYKTGDLVRFDPDGDGEPIFVGRQDQQVKLRGQRIELAEIEFNMQKHLPPDTQLAAEVIKPSGGGEQTLVAFLVEQKKNGMRHLDGNVFGSFTNKFQDALRDMTKQLFVDLPSYMIPSAYIPLWKMPLLVSCKTDRKRLREIGASVTRQDLRRFNSAVSEKKEATTEMELKLQSLWAKLLGGDADFSANDNFFSMGGDSLRAMRLVAAARDEGVVLSVPDIMLNPTLSSMAEKAKPVSAEETSDVPPFSMIAKDWDVDAARQESARLCGVDVANVEDVYPCTPLQEGLIALSAKFQDAYVAQRVATLPAETAVRLKEAFDTAVQGSPILRTRIINVSGRGLFQVVLKDGQLVREYSTEVSEYLRLDRNEPMDLGTALFRYGLVEEPGSDKMNFVITMHHAVYDGWSMPLVFDRVNRAFNGLHTERPSSFKHFIKHLISLDPADAQQYWKERLEGTIPHQFPPLPQKGYTTQADSLLEHYVTVPTSAHSKLTLATIIRGAWALVSSLYMGHPDIVFGETLTGRSAPVPGIEQIEGPMITTVPIRVRLSLDRPIAEYLQKIHAQTVKQIPHEHLGLQNIRRLSKDARVACDLRTGLVLHPKEDEDWGTVDIRNPANTFLPANDAEGAREALKFNTYALMLVCTLEENGFLVMASFDSNCISKEAMERVLAVLDRIVHAFLGNPESKLGDVAVLDPVEAQDAEAMRPRDVMSDSALGMSPVDGPESMDASLKELSPNEEKLRSILGRILGMKETDIRPSDSFFDLGGDSIGAMRLVSDARAQGLNLTVAQVFQSSSLSDLAASASNEREDKLAEILSRILGMAKTDIKSSDSFFELGGDSIGAMRLVSDARAQGLNITVAQVFQSKSLAELASSAEEETPSQPRVDTDAPFIALGKDANLHSPDRVGLYLENQGWEITNIYPTRPLQQLAVEGTVDLPRYSLRYELIKFATPIDRQRLEQACQELVARNEVLRTVFVKDDGLTLGVVLSSLVVPYTETAVPDGEDADAFIQAGIKQDIEAPKPYGSSFVAFNLFTHTNGASTLVFRISHAQYDEICLPILFEQLSALYAGTTVPETVPFSKHINHVVLDNIPKAIPYWKNLLSGSEMTVLKPSIPLTHRGPADIYKEFDISRRPANITIGSLPTAAWALVLSRRLSRTDVVFGEVVSGRNVGAPNADRIFGPTWQYIPFRVAFSKSWSYLDLLRYVQDQHMTSAAYESMGFSEIVKNCTHWDPESVQWFDTVVHQAPAWVEEMPFGNGVEAKFQTLYPHAEPLREWKCQAFVKDGGRKLGIEIVTFEEWIGEAEGVLEEVGKALECLMEGRAGESIF
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of hydroxamate-containing siderophores that play a critical role in virulence (PubMed:15755917, PubMed:17056706, PubMed:23980626).  Cochliobolus heterostrophus produces extracellular coprogen-type siderophores including coprogen, neocoprogen I and neocoprogen II, as well as the intracellular siderophore ferricrocin (PubMed:17056706).  The role of extracellular siderophores is to supply iron to the fungus during plant infection, and the intracellular ferricrocin is required for intracellular iron distribution and storage with a crucial role in ascus and ascospore development (PubMed:17056706, PubMed:17601875).  SIDA2 catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores (PubMed:23980626).  The assembly of extracellular coprogen-type siderophores is then performed by the nonribosomal peptide synthetase (NRPS) NPS6 whereas the intracellular siderophore ferricrocin is assembled by NPS2 (PubMed:17056706, PubMed:17601875).
What are the official names of this protein?
Nonribosomal peptide synthetase 6, NPRS 6, Extracellular siderophore synthetase.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.