PharMolix/UniProtQA huggingface dataset:
Protein: DXR_CAMC5
Sequence: MVILGSTGSIGTNTLEICSRHGVSVEALSCAKNIALLNEQIARFRPKFVCVADESLASEVKILKKSQIFVGAGGLLEMLEACHSQKVVNAIVGFAGLAPSLKTQELGKSLALANKESLVAGGKFLDTAKISPIDSEHFGLKFLLQNRTAPNRLIITASGGAFYRTPMKNLAKVTPSDALKHPNWSMGAKITIDSATMANKLFEVMEAFWLYGTSRIDALIEPTSMVHALVEFMDGSCTAHISRADMKLAIAHAVLENVSENVVAHADLLALKDIKFHKINLKKYPIFSLKEQVLERADLGVVINAANEVGVFAFLKGECRFLDISRIVLAAAKRFADVKIETKDEIFAIDAEVRNFTKRGLNAKI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: Y2280_LACLM
Sequence: MTFYNYLMRHRAPVEKDDATRLANLVFQDPLFPKQSKDFDEISTYLETEAPFYFNLTLFDNVWLSYLEA
What are the official names of this protein?
UPF0346 protein llmg_2280.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: TRP1_PENRU
Sequence: GPSGFLGMR
What are the official names of this protein?
Tachykinin-related peptide 1, TKRP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_MYCMM
Sequence: MSTLHKVKAYFGMAPMEDYDDEYYDDRGPSRGYSRPRFEDDYGRYEGRDFEDPRRDPRADMRADLRGEPADYPPPGGYRGGYPDEARFQPREFDRADMARPRFGSWLRNPTRGSLAMDPRRMAMMFEEGHPLSKITTLRPKDYSEARTIGERFRDGTPVIMDLVSMDNADAKRLVDFAAGLAFALRGSFDKVATKVFLLSPADVDVTPEERRRIAETGFYAYQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SELA_SHIF8
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLRRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLVAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU1_MOUSE
Sequence: MPAPTCFSCHKTRAALRRPRSGQALCGSCFCAAFEAEVLHTVLAGHLLPPGAVVAVGASGGKDSTVLAHVLRELAPRLGITLHLVAVDEGIGGYRDAALEAVRSQAARWELPLTIVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARLVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGVLGSTGEGCALPRCRPLQFASQKEVVLYAHFRHLRYFSEECVYAPEAFRGHARDLLKLLEAARPSAVLDLVHSAERLALAPAAKPPPPGTCSRCGALASHKLCQACALLDGLNRGLPRLAIGKGRRVLQVEPPQPGNPSLVTSDPVAPAGPCTCKQPKDKANPCGNGGDRAGATCVSQCDLSPGNGEDRAGATCVSQRDLSLGNGGDRAGATCVSQCDLSPVAE
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_PSEP1
Sequence: MFAPLLKKLFGSKNEREVKRMLKTVSIVNAFEEKMVALSDEQLRGKTAEFKERLAKGETLDQLLPEAFAVAREAGKRVMGMRHFDVQLIGGMTLHEGMIAEMRTGEGKTLVGTLAVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLSVGIVSAFQPPEEKRAAYAADITYGTNNEFGFDYLRDNMAFSQDEKFQRELNFAVIDEVDSILIDEARTPLIISGQAEDSSKLYIEINRLIPRLTQHIEEVEGQVTQEGHFTIDEKSRQVELNEAGHQFIEEMLAQAGLLAEGESLYSAHNLGLLTHVYAGLRAHKLFHRNVEYIVQDGQVLLIDEHTGRTMPGRRLSEGLHQAIEAKENLNIQAESQTLASTTFQNYFRLYTKLSGMTGTADTEAFEFQSIYGLNVMVIPPNKPLARKDYNDLVYLTADEKYAAIIADIKESMKLGRPVLVGTATIETSEHMSNLLKKEGIDHKVLNAKYHEKEAEIIAQAGAPGALTIATNMAGRGTDILLGGNWEAEVAALENPTAEQIAQIKADWQKRHQQVIETGGLHVIASERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDSLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEYDDVANEQRKVIYHMRNSLLAAENIGDTIVEFRKEVLDATISQHIPPQSLPEQWDVAGLEASLASDFAIKLPIQQWLDEDDHLYEETLREKLLSEITTAYTEKEDQAGLDALRTFEKQILLRVLDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFSLFQELLESIKRDTIRVLSHVQVRREDPAEEEARLRREAEELASRMQFQHAAAPGLESEQLSEEGAEVAVASAPVRNDQKLGRNEPCWCGSGKKFKHCHGQIE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GCSH_FLAPR
Sequence: MALRIWASSTANALRLSSATRPHFSPLSRCFSSVLDGLKYANSHEWVKHEGSVATIGITDHAQDHLGEVVFVDLPEAGGSVTKATGFGAVESVKATSDVNSPISGEIVEVNSKLSETPGLINSSPYEDGWMIKVKPSNPSELDSLMGAKEYTKFCEEEDSAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYC6_PROHO
Sequence: AASGASIFSAKCAQCHLGGKNIINPTKTLSLADLQANGKDTVSAI
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: LPXB_XYLFT
Sequence: MIQAPRIAIIAGEASGDHLGAGLIQQLRLHFATAEFIGIGGDMMRSAGCQTWFDTSELAVMGLTEVLRHLPRLLKIRREFCKRALAWHPDVLIGIDAPDFNLTVERWFKQRHIRTVHYVSPSIWAWREKRAAKIGASVDRVLCLFPMEPPIYARYGIDARFVGHPMADEIPYQTDRATARTALGLPLLSPVLAVLPGSRHSEISQLGNTFLEAAGQLSEHLPGLHVVIPAANTQCKPLLAEQLSRSTLPVMHSHLLDSSARTAMLAADVVLVASGTATLEAMLLKRPMVVAYKVAPLTYRIVKTLKLLKINRFALPNILAGEDLVPELIQKDCTAPALCAALLDCFKHPQKVTALQNRYLQLHTQLRRNASTRAAEAIAELLQQR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: ELP1_YEAST
Sequence: MVEHDKSGSKRQELRSNMRNLITLNKGKFKPTASTAEGDEDDLSFTLLDSVFDTLSDSITCVLGSTDIGAIEVQQFMKDGSRNVLASFNIQTFDDKLLSFVHFADINQLVFVFEQGDIITATYDPVSLDPAETLIEIMGTIDNGIAAAQWSYDEETLAMVTKDRNVVVLSKLFEPISEYHLEVDDLKISKHVTVGWGKKETQFRGKGARAMEREALASLKASGLVGNQLRDPTMPYMVDTGDVTALDSHEITISWRGDCDYFAVSSVEEVPDEDDETKSIKRRAFRVFSREGQLDSASEPVTGMEHQLSWKPQGSLIASIQRKTDLGEEDSVDVIFFERNGLRHGEFDTRLPLDEKVESVCWNSNSEALAVVLANRIQLWTSKNYHWYLKQELYASDISYVKWHPEKDFTLMFSDAGFINIVDFAYKMAQGPTLEPFDNGTSLVVDGRTVNITPLALANVPPPMYYRDFETPGNVLDVACSFSNEIYAAINKDVLIFAAVPSIEEMKKGKHPSIVCEFPKSEFTSEVDSLRQVAFINDSIVGVLLDTDNLSRIALLDIQDITQPTLITIVEVYDKIVLLRSDFDYNHLVYETRDGTVCQLDAEGQLMEITKFPQLVRDFRVKRVHNTSAEDDDNWSAESSELVAFGITNNGKLFANQVLLASAVTSLEITDSFLLFTTAQHNLQFVHLNSTDFKPLPLVEEGVEDERVRAIERGSILVSVIPSKSSVVLQATRGNLETIYPRIMVLAEVRKNIMAKRYKEAFIVCRTHRINLDILHDYAPELFIENLEVFINQIGRVDYLNLFISCLSEDDVTKTKYKETLYSGISKSFGMEPAPLTEMQIYMKKKMFDPKTSKVNKICDAVLNVLLSNPEYKKKYLQTIITAYASQNPQNLSAALKLISELENSEEKDSCVTYLCFLQDVNVVYKSALSLYDVSLALLVAQKSQMDPREYLPFLQELQDNEPLRRKFLIDDYLGNYEKALEHLSEIDKDGNVSEEVIDYVESHDLYKHGLALYRYDSEKQNVIYNIYAKHLSSNQMYTDAAVAYEMLGKLKEAMGAYQSAKRWREAMSIAVQKFPEEVESVAEELISSLTFEHRYVDAADIQLEYLDNVKEAVALYCKAYRYDIASLVAIKAKKDELLEEVVDPGLGEGFGIIAELLADCKGQINSQLRRLRELRAKKEENPYAFYGQETEQADDVSVAPSETSTQESFFTRYTGKTGGTAKTGASRRTAKNKRREERKRARGKKGTIYEEEYLVQSVGRLIERLNQTKPDAVRVVEGLCRRNMREQAHQIQKNFVEVLDLLKANVKEIYSISEKDRERVNENGEVYYIPEIPVPEIHDFPKSHIVDF
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:15769872, PubMed:18755837, PubMed:31309145, PubMed:25569479).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244).  Functions as a gamma-toxin target (TOT); disruption of the complex confers resistance to Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin) (PubMed:12424236).  May also be involved in sensitivity to Pichia inositovora toxin (PubMed:13680368).  ELP1/IKI3 binds to tRNA, mediating interaction of the elongator complex with tRNA (PubMed:24750273).  Independently, may be involved in polarized exocytosis (PubMed:15780940).
What are the official names of this protein?
Elongator complex protein 1, Gamma-toxin target 1, Protein IKI3.
What is the protein family that this protein belongs to?
Belongs to the ELP1/IKA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: IPP2C_MACFA
Sequence: MSASTSSHRPIKGILKNKSSSGSSVATSGQQSGGNIQDVKRKKSQKWDESSILATHRATYRDYDLMKANEPGTSYMNLQDDGEDSVRDVEGEDSVRGVEGKEAMAATDASDHSCEVEEEESNEAYMRKLLLHKQEKKRQFEIRRRLHYNEELNIKLARQLMWNDLQSEDDENEERPQATNEEKTAAEESEEAPLSGGLQTQSCDP
What is the function of this protein?
Functions as a protein phosphatase inhibitor.  It inhibits activity of the catalytic subunit of PP1 and weakly inhibits the activity of myosin-associated phosphates (By similarity).
What are the official names of this protein?
Protein phosphatase inhibitor 2 family member C, Protein phosphatase 1, regulatory subunit 2 pseudogene 9, Type-1 protein phosphatase inhibitor 4, I-4.
What is the protein family that this protein belongs to?
Belongs to the protein phosphatase inhibitor 2 family.
Protein: PLSX_STRP2
Sequence: MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: Y1889_COREF
Sequence: MLILLPPSETKTPGGAGAPLDLPSLSFPELTDVRESIITDLGALSPDDALPVLGISEKLRPEAVANTVLRSAPTMPAVLRYSGVLYDALAADTLTPAALNRLAIGSALFGVVRAGDHIPHYRLSGGTKLPGAQGTTPTMKARWGTTITDALAGVDELIIDLRSGTYQQLGKVPGAVTVRVESVLGDGTRKVVSHFNKHYKGELARVLATSPREATTAGEVADIARGAGMTVEINEGRKETLTLVV
What are the official names of this protein?
UPF0246 protein CE1889.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: MUTS_EHRCR
Sequence: MNHDSKITPIMQQYMMLKSQYKEYLLFYRLGDFYELFFDDAIETSRILNIVLTKKGNVPMCGVPFHSSESYLNRLVKLGYKIAICEQLETSEEAKKRGYKALVKRDVVRIVTPGTILEDSLLEAKENNYLSCIVNVDHNYAIAWLELSTGLFYYHTTELHKLDSDLFRINPKEVLISDKLVELDSIYSILRKYKFSVTQYSGSFFDVSRSYNTLCNVYGISTLKGLGDLKNEEIAVCGSLLEYVKATQKGNLPQLEFPKAYSKGDFMFIDAAALRNLELFCTQSGDLEGSLISSIDYTITACGGRLLKRCLSAPLACSHAINRRLDIVEFFVNDRTLCRGVRETLRGIADIERILTRIKVGKCSPKDLYALKLTLDKIFVLLDLLHKFDSSVVGDFCSRLGKYDDLCKTLDDVLIPNNVNNVKDGGFINPDYDAQLSEYIYIQSYSNDLIQELRDKYRNITNIQSLKILYNNILGYYVEVSSSYLISDKDFIHRQTLANSIRYTTSELKALESKIISARDAAINLEVKIFGQLCTCIIEVADKITMTAHAIAEIDMLTSFAELAIQYSYTKPIVDDSYEFNIKKGRHPVVERNGKFVANDIDLSLMQRVHLITGPNMAGKSTFLRQNALIGILAHIGSFVPAQHAHIGVIDKVFSRVGASDNIASGHSTFMVEMTETAAIINQATDKSFVILDEIGRGTGTYDGLSIAWSVIEQIHNVNKSRAIFATHYHELSKLDRYLENIKCFCMKVEEWNGKVVFLHEIIPGSTNKSYGIHVAKLAGFPQSVLDRAEDLMSKLKANEDLLT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CAC1A_DROME
Sequence: MGGPKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQIGPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKSKSTDTEEEEAEEDYGDDGYLKTRSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQELTAAEEEQVEEDKEKQLQELEKEMEALQADGVHVENGDGAVAPSKSKGKKKEEEKKEEEEVTEGPKPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDSGMPMLELQDASRHPSQESLTGADAGHLHPGHSYMNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKETRHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYGTTSLCQRSRSPSPARLQEMRERDRLGYGIDMGVTHVQHSYPTLASRRAGIGRRLPPTPSKPSTLQLKPTNINFPKLNASPTHTHHSTPHSVHSLPHHRDLLRDPRDMYYSSRERERDRERLRDRDRDRDRDRLHEYDLRYEYRDRERELYERERDREREVERERLEYIAPLSFEQALAMGRTGRVLPSPVLNGFKPKSGLNPRHSDSDEEDWC
What is the function of this protein?
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity).  Probably encodes a dihydropyridine-insensitive current.  Vital for survival to adulthood.
What are the official names of this protein?
Voltage-dependent calcium channel type A subunit alpha-1, Protein cacophony, Protein nightblind A, Protein no-on-transient B, Dmca1A.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HOLA_BUCAI
Sequence: MKNIYPNELKKSLMQKLHYFYIFLGEDFFLLEKNQDMILNFAYKKGFLEKIIIDVEKNQDWKKIILFYKTNNLFFKKTTLVINFLIKKLNVILIQNLNKMFSLLHPDILIILKFNHLSRFIQKNKSLKEFKNYNIVSCFTPYNLNFINWIKYEIQEKKINIEEKAFFLLCKYYEGNTLFIYKILDMLFIIWPDTCITEKKIKKIIIEFFDVSPSYWINSIFQGKTEKSFYILNIFFKKKYNPLILVRSLQKDLLQLIHMKREKKISIYVMLEKYNIFVTRRKFFIKAFNKINNDSLLKAIQILVKIEVNIKKKYNNYVWNQLQELILILCN
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity).
What are the official names of this protein?
DNA polymerase III subunit delta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase HolA subunit family.
Protein: GLCU_STAAS
Sequence: MQFLDFLIALLPALFWGSVVLINVFVGGGPYNQIRGTTLGALIVGLGLLITGFAKFNNPTVIIVGLISGALWAFGQANQLKSISLIGVSNTMPVSTGMQLVGTTLFSVIFLGEWSSMTQIIFGLIAMILLVTGVALTSLKAKNERQSDNPEFKKAMGILIVSTVGYVGFVVLGDIFGVGGTDALFFQSVGMAIGGFILSMNHKTSLKSTALNLLPGVIWGIGNLFMFYSQPKVGVATSFSLSQLLVIVSTLGGIFILGERKDRRQMTGIWAGIIIIVIAAIILGNLK
What is the function of this protein?
Involved in the uptake of glucose.
What are the official names of this protein?
Probable glucose uptake protein GlcU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_DESHY
Sequence: MNRRAVLSVSNKTGLVELARGLVELGFDLISTGGTFKTLTEAGLPVRYVTEVTGFPEILDGRVKTLHPRIHGGILARATAEHLQQLEDNGIGLIDLVVVNLYPFKETIARPGVSFQEAIENIDIGGPSMVRAAAKNQERVSIVVNPERYPEVLQALREQGEISYDMRKRLAAEAFAHTAEYDQCIAGYLTAALAEESVSSSSSPFPATITLGGQKAQDLRYGENPAQKAAFYRGADAAGTLAYGEQIQGKELSYNNWMDMDAAWGIVQDFSEPACAIIKHTNPCGTALGKTALEAYEKALAADPVSAFGGIIAFNRTVDAECAASLKAHFYEVIVAHEFSSDARAILQEKKNLRLVKVAQDGKPAHTPWKVRSIQGGFLIQEEDEGTTPISAWEVVSKRQPEPEELRELDFAWRVVKHVKSNAIVLAKAGQTLGVGAGQMNRVGSVKIALEQAGDKAQGAYLASDAFFPFPDSLEEAAKAGVRAVVQPGGSVRDAEVIEAADRLNLIMVFTNRRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CWC15_PONAB
Sequence: MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Spliceosome-associated protein CWC15 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC15 family.
Protein: SECA1_STRA5
Sequence: MANILRTVIENDKGELKKLDKIAKKVDSYADHMAALSDEALQAKTPEFKERYQNGETLDQLLPEAFAVVREASKRVLGLYPYHVQIMGGIVLHHGDIPEMRTGEGKTLTATMPVYLNAISGLGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPFEKREAYNCDITYSTNAEVGFDYLRDNMVVRQEDMVQRPLNYALVDEVDSVLIDEARTPLIVSGPVSSEMNQLYTRADMFVKTLNSDDYIIDVPTKTIGLSDTGIDKAENYFHLNNLYDLENVALTHYIDNALRANYIMLLNIDYVVSEEQEILIVDQFTGRTMEGRRFSDGLHQAIEAKESVPIQEESKTSASITYQNMFRMYHKLAGMTGTGKTEEEEFREIYNMRVIPIPTNRPVQRIDHSDLLYPTLDSKFRAVVADVKERYEQGQPVLVGTVAVETSDLISRKLVAAGVPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGTDRIKVVLERMNLAEDDTVIKSKMLTRQVESAQRRVEGNNYDTRKQVLQYDDVMREQREIIYANRREVITAERDLGPELKGMIKRTIKRAVDAHSRSDKNTAAEAIVNFARSALLDEEAITVSELRGLKEAEIKELLYERALAVYEQQIAKLKDPEAIIEFQKVLILMVVDNQWTEHIDALDQLRNSVGLRGYAQNNPIVEYQSEGFRMFQDMIGSIEFDVTRTLMKAQIHEQERERASQHATTTAEQNISAQHVPMNNESPEYQGIKRNDKCPCGSGMKFKNCHGLRCLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RL7_KINRD
Sequence: MAKLSTDELLDAFKELTLIELSEFVKKFEETFDVTAAAPVAVAAAGGAAGAPAEAAEEQSEFDVILESAGDKKIGVIKEVRALTSLGLKEAKDLVDGAPKPVLEKVAKDAAEKAKAQLEGAGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL32_IDILO
Sequence: MAVQKSKKSRSRRDMRRSHDAIDGPTLSVDSTTGETHRRHHVTADGYYKGRKVVNK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RTN2_XENLA
Sequence: MGHVLSFTHCKDAPSTASSTPDSCPLEGEDDDTPVTEVDFWPLPSPHEPTFSYITIGSSAPLSRPPVRARRGLGQGRVHEAPREETEEKEVKDVVNYVLLENTCELKQISPLQVQEEVVFVAKPQPQVEVFRAVKDLLYWRDTLLSTGCLTGVTLSLLCLSQFSVISVFAYGCLIILSVTLTLRLYTKLLHALKRGNGANPFQYYLDTDLKLTTKQAEEIVARAFSLASTTLCTLRSLFLVEELKDSLKFLVIVYLLTYVGAVFNGITVLLLCVIGAFTFPILYKQHQTQVDHYVSLVSKKVNAFRSKFQGAAKKPPAKQK
What is the function of this protein?
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity).  Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity).  Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity).
What are the official names of this protein?
Reticulon-2, xRTN2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton.
Protein: CYNS_MYCA9
Sequence: MVHAQFDPTSREELAIAAVEAKIAKDLSWQQIADAAGYSPAFVTAAVLGQHPLPPRAADTVAGLLGLGDDAALLLQTIPTRGSIPAGVPTDPTIYRFYEMLQVYGTTLKALIHEQFGDGIISAINFKLDVRKVPDPDGGYRAVVTLDGKYLPTVPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.