PharMolix/UniProtQA huggingface dataset:
Protein: PANB_YEAST
Sequence: MNIMKRQLCTSSKRFFSTAKNVVKYNTIQDIRNKYFTGTPLSMCTAYDFITATWVNKANCDLLLVGDSLAMTSLGYDSTITLSLNEFKYHVASVCRAEGSSMVVVDMPFGTFESGISDGLKNAIDIMKLDSKVTSVKVEVGSYTKDKYAMKFIEELCSRGIPVMAHIGLTPQKVHSLGGYKVQGSKSLLQMQELYETAMQLQKIGCWSILIECVPHKMAQFITSKLSVPTIGIGAGNGTSGQVLVISDLLGMQGDSVPKFVKQAVNMTDIATQGLKEYIASVEDRTFPERGTHTFKVKEDLWNEFLSSINEK
What is the function of this protein?
Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase required for pantothenic acid biosynthesis (PubMed:11154694).  Acts downstream in the pantothenic acid pathway (PubMed:11154694).
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Extracellular matrix protein 31, Ketopantoate hydroxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
Protein: POL1_TOTV
Sequence: MSFSKMFPGFNSVTEKCATSSSGSFFSELTASISNFSRTLSNVTKVSSQISSHIEDLKPSVTDAASSFTSTCNSVTKLLDKIMTLIEPFIKAYSFVASMYKSICDMVAKIVASIKDKFTLGFNWVLDKSEDVDVLVIAFLIFAISMLIIVFICPSSVLDGVVQMTHIVFNTVGNFFSALYKLDWLPTWSQKFSMMAQANVLPGESMSHSPLSQVVASLIAFGISTLVFVAVPGRPNGLSNPLSKILYSAGSGAQQCNQLFTLFRNMKDCTSQAFSWVLEIIVDIFGFKNPVLSAISATLSTDLFTWMEEVDAVCDPAHRLENFANPAFTIKLQHLREQALKISAYIATHPVAAFMSHRVTAAIXHLDKIYGENCQHTGVGQYRAEPFMVQWYGASGCGKSTSMRLFINDVLDRMEEPKLNRLYAVSKRDAYWSNYAHQTAILMDDMGALRDGAGQCQDIKDLIDIKSTQPAPLPMAAVEDKGRHFTSRYIFATSNLISAPAQCGLTYPDAFERRRDVLVECRKVGEFNTDAPTSHLEFDVVESKRPHAITHRGLSYDDLLEYVVAKCKVHAEISGKLYGATSGKVAQVDVSPEEIIASMDMLNIQDTKQDAKLPVVVVSEEDRVAYSQELTVEALKYAYQGSLNPAAYFPHDMHKQAIFDVLSESAKETFTRWVNDMLYQGCCNENYRWLIKNIPADYIMHFKSFIYASTINERSFDVQKQLPDGMAHRAIDADVDTLICVEQMPAHVQFLYTAFVRYWCRRKMEQPRQSWVVVCYHSIVDYIKNAWYDLPYILRVLIKAGLILIALNGAFGAVTAFCACWQSNTFPSAEGRGGITNESNSISSRKNKGKSIFARSLLAQAKGDMLEKWASDDGFINEGLKKNLVVLRLGEGVYFRGTYVCSGWVMTVAHAFSSLRDGTTFSIIHAQSISKVQYNAKTARFLKEQDIVLLNVGNPDGPKPDIRKHFPVRDGVCFSKGTQGVCVRAVASKDASQGNLEYLRFNVMMSKGYLEKVTYQMDSSSFKLESQASYEYHMNGENGDCGTLLLLPNVQDKQPCIVGIHCASYDEEAAHKGFVASNATAIFRDQLEDLPTGPVKVAMVRCQLLKDLRARDAALFEEKQVAFVGTLPAEQAATVPHKTTLRRSGLFEAFGPAETAPSIISASDKRGEGFDPYVAGIQKYNETAQNFDEDIARLAYEGLRQAILPVLHSQRVPFGKPVTQNEDVVLNGVDGFDYFDGMELSTSCGYPYNKLGMGTSKREFVEPSGDGDRVQLKRTTPIFDDWEALDVEIRKGNFVELVTTQCAKDERLPLEKVFGKRKTRLFEILPFHYNMLVRKYFLDFSASLMASHNALPCKVGINPGGIEWTLLANGFRAVSDTGFSADYSSFDGRAPIFAFQWFCDLVDDYYGSPPGSPDSNARHVLLMMASCHYTICENKVFRLVGGMPSGFALTVIFNSLLNEFYMRYAFISLLRRPHIAAQAIGCKPSDFNKLFVAVYGDDNLVAVPMELHWYTLPAIAQELEMVNVIIKNGIDKNMDVSSSKMLDLSELTFLSRGFKRHRLGYVQAPLKWVSIIEPMYWIRPSVGCPDALAMLENIDTGVREAFHHGPQVFEKLVTDVQNALKERCFPATTFPTYFELEQDWLVEVTGNPAIGLIKELHIAASAFVPLPPGNTVLNFSDGVHTFADRVSFCSSRTAAAQQWDTTTVLVNCTGAKRPTWVRGPTTWRDFEGLIWPYTMAAIKDHICSIVTKGVTKPHVVFVCGNGYAIGPVCAALYCLSTGQYSSQDVVVRLRTIADVTDLSQYPGGCAKYLLKCADTREEELADTCKIAQAKGETPAYIPQGGFSLGNFRIVQGRIDLQLAQRLPFTVGPYGGWGQHTTRELKLLLKDMEKIYQILVQRESFITLYFDYLSSEQVMLLVDFLRLQGFFPRQNDVDYLLKAFKLSKQRHNKENCHTVYFRKPFLSRKMTMGSKEILSATAAESLFGMDVSANVLKSRLLHLQKPIKCSSMELAFKIYCVIQGHLSKEVVTHFQRMYQQDLTEGIIEKVILWLTATLSESFPVDLVDVPLGLDNIEIQDKGFSLNPNNINMNACDAILFQLTECYNRSTKKHVFCRYTTASSLVVAYVLAHRHQTIDELPSFYATHPDVLLLTPILTGYKAP
What is the function of this protein?
Picornain 3C-like protease is a thiol protease that probably cleaves the polyprotein.
What are the official names of this protein?
RNA1 polyprotein.
What are the subcellular locations of this protein?
[Putative helicase]: Host membrane; Single-pass membrane protein.
Protein: RS13_PROA2
Sequence: MRIAGVNLPLNKHAVIALTHVYGIGKTSARNILERAGIDPAKKIAEMSDEEAHAIREIIAEEYKVEGQARGLQQLAVKRLMDIGCYRGLRHRRSLPVRGQRTQTNARTRKGKRKTVAGKKKAVKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: U76H1_STERE
Sequence: MLQLATYLHSQGISITIAQYPNFNSPDSSNHPELTFLPLSSGNLSVADISGGFFKFIQTLNHNCKPHFREYLVQNMSSDDKESIVIIRDNLMFFAGEIAGELGLPSIILRGSNAVMLTASDIIPQLHQEGRFPPPDSLLQETIPELVPFRYKDLPFIGYPIHQTLEFSITMMTPKSPASAILINTLEFLEQSALTQIRDHYKVPVFTIGPLHKIVTTRSTSILEEDTSCINWLDKQSPKSVVYVSLGSLAKLDEKVASEMACGLAMSNHKFLWVVRPGMVHGFEWVEFLPDSLVGEMKARGLIVKWAPQTTVLAHNAVGGFWSHCGWNSTIECLAEGVPMMCQPFFADQLLNARYVSDVWKTGFEIVIEKGEIACAIKRVLVDEEGEEMRQRAMEIKEKVKIAINDGGSSYDSFKDLVAFISSL
What is the function of this protein?
May glycosylate diterpenes or flavonols in leaves.
What are the official names of this protein?
UDP-glycosyltransferase 76H1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PMA3_NICPL
Sequence: MGEKPEVLDAVLKETVDLENIPIEEVFENLRCTKEGLTATAAQERLSIFGYNKLEEKKESKFSKFLGFMWNPLSWVMEAAAIMAIALANGGGKPPDWQDFVGIITLLIINSTISFIEENNAGNAAAALMARLAPKAKVLRDGKWKEEDAAVLVPGDIISIKLGDIIPADARLLEGDPLKIDQSALTGESLPVTKGPGDGVYSGSTCKQGEIEAVVIATGVHTFFGKAAHLVDSTNQVGHFQKVLTAIGNFCICSIAVGMIIEIIVMYPIQHRKYRPGIDNLLVLLIGGIPIAMPTVLSVTMAIGSHRLAQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLTVDKYLIEVFARGVDADTVVLMAARASRTENQDAIDAAIVGMLADPKEARAGIREIHFLPFNPTDKRTALTYLDGEGKMHRVSKGAPEQILHLAHNKSDIERRVHAVIDKFAERGLRSLAVAYQEVPEGRKESAGGPWQFIALLPLFDPPRHDSAETIRRALNLGVNVKMITGDQLAIGKETGRRLGMGTNMYPSSALLGQTKDESISALPVDELIEKADGFAGVFPEHKYEIVKRLQARKHICGMTGDGVNDAPALKKADIGIAVDDATDAARSASDIVLTEPGLSVIISAVLTSRAIFQRMKNYTIYAVSITIRIVLGFMLLALIWQFDFPPFMVLIIAILNDGTIMTISKDRVKPSPLPDSWKLAEIFTTGVVLGGYLAMMTVIFFWAAYKTNFFPRVFGVSTLEKTATDDFRKLASAIYLQVSTISQALIFVTRSRSWSFMERPGLLLVVAFFIAQLVATLIAVYANWSFAAIEGIGWGWAGVIWLYNIVFYIPLDLXXFLIRYALSGKAWDLVIEQRIAFTRKKDFGKEQRELQWAHAQRTLHGLQVPDPKIFSETTNFNELNQLAEEAKRRAEIARLRELHTLKGHVESVVKLKGLDIETIQQAYTV
What is the function of this protein?
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump.  The proton gradient it generates drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
Plasma membrane ATPase 3, Proton pump 3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSBA_HAHCH
Sequence: MSKVAKQYAGAQVYGRLLSYLKPLWKVFALAVLGNVIYALASAAMADATKYIVAAIETPSPEGRLLVPMLIIGIFALRGLGSFCGGYFMARVARGIVHRMRLELFRHLTVLPCRFFDSNSTGHLVSRITYNVDQVTGAATNAITVVLREGFTVIGLMGYMIYVSWKLTLLFLVLGPIIGVLIGYVSKRFRRISRRIQSSMGDVTHVASESIGGYRVMRTFGGEEYEFNRFMKASEYNITQALKMSLTQALSTPIIQLVISVFIALLVWLALSPEVRGNMSTGEFLAYITAATTCAKPIRQLTEVNAVIQRGISAAQDVFMQLDEPVEKDEGSYVADRVQGRLEFKSLGFAYSDEGKPALQEINLVIEPGETVALVGRSGSGKSTLVNLLPRFYDYEQGEILLDGKPLKDFALTSLRRQISIVTQQVVLFNDTVTNNIAYGALADATPEQVREAAKSADALGFIEQLEQGFDTLLGENGTRLSGGQRQRMVIARALLKDSPILILDEATSALDTHAERNIQSALETLMKGRTTLVVAHRLSTIENADKIVVMDQGRIVEVGSHRELIEKDGAYAALHKLQFSEADA
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: JZT59_CHIGU
Sequence: MRYQTVFWILLIALCTVNPAKIQDVASYGGTVRLTDSGRAKCSRKTWPCETSEDCCDKNCSDTFWTCQLGYGCSRVCV
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U29-theraphotoxin-Cg1a, U29-TRTX-Cg1a, Jingzhaotoxin-59, JZTX-59.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 13 (insecticidal toxin ABC) family. 03 (JZTX-59) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIR2_EBVA8
Sequence: MSKLLYVRDHEGFACLTVETHRNRWFAAHIVLTKDCGCLKLLNERDLEFYKFLFTFLAMAEKLVNFNIDELVTSFESHDIDHYYTEQKAMENVHGETYANILNMLFDGDRAAMNAYAEAIMADEALQAKISWLRDKVAAAVTLPEKILVFLLIEGIFFISSFYSIALLRVRGLMPGICLANNYISRDELLHTRAASLLYNSMTAKADRPRATWIQELFRTAVEVETAFIEARGEGVTLVDVRAIKQFLEATADRILGDIGQAPLYGTPPPKDCPLTYMTSIKQTNFFEQESSDYTMLVVDDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: FOLD_PARPJ
Sequence: MTAKLIDGLALSKTLRADVAARAAALTARGHQPGLAVVLVGDNPASEVYVRNKVKACHDNGLGSSFDRYPADLPEAELLARIDELNRDPRIHGILVQLPLPPHIDSHKVIEAIAPEKDVDGFHVANAGALMTGRPLFRPCTPYGVMKMLAAYEIPLQGANAVVIGRSNIVGKPMALLLLEAGATVTICHSKTRDLAAHTRNADVVVAATGLRNILTAEMVKPGAAVIDVGMNRDDAGKLCGDVDFAGVKEVAGYITPVPGGVGPMTITMLLVNTIEAAEREAAANA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ATPB_YERPP
Sequence: MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPXC_CAMLR
Sequence: MNQTTIAKEVKGIGIGLHKGEPISIKLEPLEAGSGIVFYRSDLGISYEAKPENVIDTQMATVIGDHRGYVSTIEHLMSAINAYGIDNVRIVLDANEAPVMDGSSIGFCMMLEEAGIKELDVAKKILVIKKSVEVKEGNKFVRLSPTDMPIINYTIEFDNPIIGKQNYCFEFSKQNYIEQIARARTFGFLKDVQALRAMNLGLGGSLENAVVIDDNRILNPEGLRFKDEFVRHKILDAIGDLTLLGCRVFGDYTSYAGSHKLNHLLTKELLKDPSAYEVVSLEKSTYKVYEKVFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL22_METSB
Sequence: MSKEKTPRALKDNEAKAVARMLRISPQKLNLLAQLIRGKKVERALAELEFSRKRAAFDVRKTLESAIANAENNHSLEVDDLVVAEAFVGKALVMKRFSPRARGRSGKIQKPFSHLTIVLREVAVAAQA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y4010_BACAN
Sequence: MAMRFLNIGYGNIVSAHRIIAIVSPESAPIKRTVQEAREHNALLDATYGRKTRAVIVMDDGHVVLSPIQPETIAHRLNNKEDLSEEG
What are the official names of this protein?
Putative regulatory protein BA_4010/GBAA_4010/BAS3723.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: CLPX_SHEB8
Sequence: MGDNKNNGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKRDSDKLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTGSGKTLLAETLARSLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLEKVIEQRAHVGSGIGFGAQVKGEKEKATISETLTQVEPGDLVKYGLIPEFIGRLPVVATLTELDEEALVQILSQPKNALTKQYSALFEMEGVELEFREDALKAIAHKAMSRKTGARGLRSIVESILLDTMYDIPSVDGVVKAVVDESVVKGESAPILIYEHNEAQAVSGEQ
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AROC_GLOC7
Sequence: MGNIFGHLFRITTFGESHGGGVGVVIDGCPPRIEISETEIQLELDRRRPGQSKITTPRQESDTCEIISGVFEGKTLGTSIAILVRNKDARSQDYDEMALKYRPSHADATYDAKYGIRNWKGGGRSSARETIGRVAAGAIAKKILQQVAGVEIVAYVKRIKDLEAIINPETVTLEEVESNIVRCPDQDAAQKMIDLIDQTRREKDSIGGVVECVMRNVPKGLGEPVFDKLEADLAKGMMSLPATKGFEIGSGFAGTLLTGSEHNDEFYTDEAGNIRTVTNLSGGIQGGISNGENIIIRVAFKPTATIGKEQQTVTQTGEETTLAAKGRHDPCVLPRAVPMVEAMAALVLCDHLLRHHGQCKTV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UVRC_CHLPD
Sequence: MDSNPLHHSNPPVGSLPLDKVASLPSSPGVYQFKNAQGRVIYIGKAKNLRNRVRSYFRNPQQLFGKTLVMVGKIADIEVIITSSEVEALILENNLIKELKPRYNVNLKDDKTYPYLVITNEPFPRILVTRQVKKDGSTWFGPYTEARQLRSILDFIGSIFPIRSCKLRLSPENISRGKFKVCLDYHIHKCKGPCEGLLTEEEYLLMIVEITRLLKGKTSATIRSLNERMLSFAKELKFEQAAELKTQIDSLKRYAERQKVVTSDTLDRDVFAVASRNDDGCGVVFKIREGKLLGSERLYMNNTEGVSVQDLLARVVERYYLETCNLLPDEIFLQTELPAEEKETLENLLISKISAEGKQKRTIRLTVPIIGEKAHLIQLCRENARHHLEEYLIQKQKRGEALREHSGLIALAELLHLPKTPNRIECFDNSHFHGTDYVSSMVAFVHGKAKKSDYRKFKLKTVQGSDDYAAMHEVLTRRYSGTLSVELPLPDLIVVDGGKGQLSTAVKVLVSLKLDIPVIGLAKRIEEIFTPHTSDPFNLPKTSPALKLIQQLRDEAHRFAVTYHRKLRTERTLETELTTIQGIGEKTAQKLLRHFGSVDLIRTAGVDELRAAAGNKTAALLYRFYHPLEEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXPH3_HUMAN
Sequence: MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISPKSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG
What is the function of this protein?
May be signaling molecules that resemble neuropeptides.  Ligand for alpha-neurexins (By similarity).
What are the official names of this protein?
Neurexophilin-3.
What is the protein family that this protein belongs to?
Belongs to the neurexophilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTTG1_PANTR
Sequence: MATLIYVDKENGEPGTRVAAKDGLKLGSGPSIKALDGRSQVSTPRFGKTFDAPPALPKATRKALGTVNRATEKSVKTKGPLKQKQPSFSAKKMTEKTVKAKSSVPASDDAYPEIEKFFPFNPLDFESFDLPEEHQIAHLPLSGVPLMILDEERELEKLFQLGXPSPVKMPSPPWESNLLQSPSSILSTLDVELPPVCCDIDI
What is the function of this protein?
Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair.  Probably acts by blocking the action of key proteins.  During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.  At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1.  Its function is however not limited to a blocking activity, since it is required to activate ESPL1.  Negatively regulates the transcriptional activity and related apoptosis activity of TP53.  The negative regulation of TP53 may explain the strong transforming capability of the protein when it is overexpressed.  May also play a role in DNA repair via its interaction with Ku, possibly by connecting DNA damage-response pathways with sister chromatid separation (By similarity).
What are the official names of this protein?
Securin, Pituitary tumor-transforming gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the securin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPX4_HUMAN
Sequence: MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF
What is the function of this protein?
Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity).  Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (By similarity).  Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity).  Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (PubMed:24439385).  The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity).  The presence of Sec at the active site is also essential for the survival of a specific type of parvalbumin-positive interneurons, thereby preventing against fatal epileptic seizures (By similarity).  May be required to protect cells from the toxicity of ingested lipid hydroperoxides (By similarity).  Required for normal sperm development and male fertility (By similarity).  Essential for maturation and survival of photoreceptor cells (By similarity).  Plays a role in a primary T-cell response to viral and parasitic infection by protecting T-cells from ferroptosis and by supporting T-cell expansion (By similarity).  Plays a role of glutathione peroxidase in platelets in the arachidonic acid metabolism (PubMed:11115402).  Reduces hydroperoxy ester lipids formed by a 15-lipoxygenase that may play a role as down-regulator of the cellular 15-lipoxygenase pathway (By similarity).
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm.
Protein: YP071_YEAST
Sequence: MSSRFARSNGNPNHIRKRNHSPDPIGIDNYKRKRLIIDLENLSLNDKGPKNGHADDNNLIHNNIVFTDAIDDKVLKEIIKCSTSKRGDNDLFYDKIWERLREKRLQIIKWVDYKEIAYLSWWKWFHNQMTSKYTYDGEADTDVEMMAVDTDVDMDA
What are the official names of this protein?
Uncharacterized protein YPL071C.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MIAA_PHOLL
Sequence: MSDQKTQHLPTAIFVMGPTASGKTALSVALRQHLPVELISVDSALIYRGMDIGTAKPTTEEQALAPHRLINILDPSQPYSAADFCHDALKEMAEITASGRIPLLVGGTMLYFKALLEGLSPLPSANPVIRAQIEQQAAEQGWDALHQQLQKIDPAAALRIHPNDPQRLSRALEVFLISGKTLTELTTLSGESLPYRVHQFAIAPAKRELLHQRIEARFHQMLESGFEEEVKALYARHDLHVDLPSIRCVGYRQMWSYLSGEIDYDEMIYRGICATRQLAKRQITWLRGWKSVHWLDSSQPEQALSTVMQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL1D1_YEAST
Sequence: MVESNDIIKSGLAEKALKALILQCEENPSLKNDKDIHIIINTGKKMGINRDNIPRIIPLTKYKLFKPRDLNILLITKDPSALYRETLTKDEHTSELFKEIISVKNLRRRFKGSKLTQLYKDFDLVVADYRVHHLLPEVLGSRFYHGSKKLPYMIRMSKEVKLKRQQMVEKCDPIYVRAQLRSICKNTSYIPNNDNCLSVRVGYIQKHSIPEILQNIQDTINFLTDKSKRPQGGVIKGGIISIFVKTSNSTSLPIYQFSEARENQKNEDLSDIKL
What is the function of this protein?
Involved in rRNA-processing and ribosome biosynthesis.
What are the official names of this protein?
Ribosome biogenesis protein UTP30, U3 snoRNP-associated protein UTP30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PUR7_RHOOB
Sequence: MRPSLDSYAHLAGGKVRDLYTIDDEHLLLVASDRISAYDHVLSTPIPDKGRVLTAMSVFFFGVLGGNNHLAGEPDDSRIPEEVLGRALVVRKLNMVPVECVARGYLTGSGLIDYNETGAVCGVALPEGLVEASQLPDPIFTPARKAELGEHDENISFEAVVEKVGQDLAVKLRDDTLDVYGRASNFAADRGIILADTKLEFGLDAQNNLILADEVLTPDSSRYWPADGYEAGKVQPSFDKQFVRNWLTGPESGWDRASDTPPPPLPAEIVEATRARYIEAYERISGLSFADWVG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: HPRL2_NATMM
Sequence: MDRLLASLDDAPIVDKDGYEYLVHPISNGVPMLDPALLREVVIEVMQTADLNVDKIVAPEAMGIHLATAVSLQTDIPLVVIRKREYGLEGEVSLHQETGYSESEMYINDVEPGDRVVIIDDMLSTGGTLASICTALDDIGADISDIVVVMRKVGPSALDDTEFDATSLIDITVEDGEVVVH
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: 3SX1_OPHHA
Sequence: LICHRVHGLQTCEPDQKFCFRKTTMFFPNHPVLLMGCTSSCPTEKYSVCCSTDKCNK
What is the function of this protein?
This toxin binds and inhibits rat muscle adult alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE (IC(50)=3. 1 uM) and fetal alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND (IC(50)=5. 6 uM) nicotinic acetylcholine receptors (nAChR) (PubMed:26448325).  It shows a very low inhibition on rat neuronal alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (IC(50)=50. 2 uM) nAChR (PubMed:26448325).  It does not inhibit human glycine receptor (homopentamer composed of alpha-1 subunits), but seems to potentiate it (about 2-fold increased activity).  It binds to the acetylcholine-binding pocket and acts as a competitive antagonist (PubMed:26448325).
What are the official names of this protein?
Neurotoxin Oh9-1, OMEGA-neurotoxin Oh9-1, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.