PharMolix/UniProtQA huggingface dataset:
Protein: PSBJ_SYNJB
Sequence: MTSQARIPLWIVAVVAGLGVITVVGLFFYGSYVGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ACT1_PEA
Sequence: MADAEDIQPLVCDNGTGMVKAGFAGDDARAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTESLMKILTERGYMFTTSAEREIVRDIKEKLAYVALDYEQELETAKSSSSIEKNYELPDGQVITIGAERFRCPEVLFQPSMIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKAEYDERGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ARGD_GEOSE
Sequence: MSALFPTYNRWNIAVQSAEGTVVTDVNGKQYLDFVSGIAVCNLGHRHPHVQKSIEQQLNQYWHVSNLFTIPIQEEVASLLVAHSAGDYVFFCNSGAEANEAALKLARKHTGRHKVITFRQSFHGRTFATMAATGQEKVHSGFGPLLPEFIHLPLNDVDALKQAMSEEVAAVMLEVVQGEGGVRPVDPAFLQTASELCQQHGALLIIDEVQTGIGRTGKPFAYQHFDVEPDIITAAKGLGSGIPVGAMIGKAFLKESFGPGVHGSTFGGNPIAMAAAKATLEVVFDPAFLQDVQEKGRYFLARLHDALASLDIVKDVRGLGLLVGIECQTDVAPLLPLIHENGLLVLSAGPNVIRLLPLVVTKAEIDEAVDILTNVLNNANASAVL
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_BRUME
Sequence: MPRYKLTVEYDGTPYVGWQRQENGHAVQGAIEQAFKKFCGEDLTLSAAGRTDAGVHATAQVAHVDLAKDWGAGKVRDAVNAHLVMADERISILNVEKTTDTFDARFSARARHYLYRIHNRRAPLAVDYQRAWWVQKQLDADAMHEAAQRLLGEHDFTTFRATQCQAKSPVKTLDRLDVTRNGDMVEMRVSARSFLHNQVRSFAGSLMEVGVGRWTADDLQAALEARDRKACGQVAPPYGLYLVGVDYAFPF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: COAD_HAEDU
Sequence: MSYTVIYAGTFDPITNGHLDIITRATKLFAKVIVAVAQNPTKQPLFSLSERTALVAQSCSHLTNVEAVSFSGLLADFARQHHAKALIRGIRGSDDIEYEIQLSQLNNKLADGLETVFLPPAVEWRYLSSTMIREIYYHQGQVNAFVPTAVVQALQNRKNNE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_ACTP2
Sequence: MNYNDKSLSALKLGQKTEYKSEYDPTLLQPVPRKLNRDGLGITEQQPFDRGADVWTCYELSWLNENGLPQVAIADVAIDFRSENLIESKSFKLYLNSFNQTKFASLEQVEQTLAKDLSQCASGQVSVKVYKLSAYTQQPIVDFAGECIDEQDIQIDSYEFSNEHLASVAEGEVVEETLVSHLLKSNCLITSQPDWGSVQIHYVGKKLNREKLLRYLVSFREHNEFHEQCVERIFIDLIQFTQPEKLTVYARYTRRGGLDINPFRSNFESVPQNLRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_YERPP
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_BURVG
Sequence: MTDTLFDRRDIDALLGGRHPDPFACLGPHGEAGRTVVRALLPGALRVRAVTPGGDELGALACVDEAGCFAGTITHDGRYRLAIDWPDAQQVTDDAYAFGTLLDDAALARFAAGDPAAVLDCLGATPIRVDGVDGVRFAVWAPNAQRVSVVGNFNSWDGRRHPMRLRRPWGVWELFVPGIGPGEHYKYELCAADGSLLPHKADPCARATEAPPRTASVVADTAALDGFGWHDAGWIDARPDAGRRFRVPWSIYEVHAESWQRVPEEMDRSATWDELAERLIPYVKGMGFTHVEFMPISEYPFGGSWGYQPLAQFAPSARFGPVDGFARFVDRAHAAGIGVIVDWVPAHFPNDAHGLAQFDGSALYEHADPREGMHPDWNTCVFNLGRNEVSAFLIASALAWARRYHVDGIRVDAVASMLYRDYSRKEGEWVPNVYGGRENLESVAFLRTLNDALHGAAAPAGVVTIAEESTAWPGVTAPTGDGGLGFDFKWNMGWMHDTLAYLHEDPIHRRYHHDRMTFGLVYAFSERFVLPLSHDEVVHGKGSLAAKMPDDAWQRLATLRAYFGFMWAHPGKKLLFMGSEFAQWSEFAHDGTPHWDLLDAPAHRGVQRLVRDLNRAYASEPALHALDCDAAGFTWLIGDDRDNSVLAFARRDDSGRVVVAICNFTPVPRSGYRVGLPAPGQWRELMNTDAAVYGGSNAGNDGAVWAQDVPAHGQPWSATLRLPPLATLWLAPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MTNB_ASHGO
Sequence: MDAAAQTSLVVSEDRRHPANVICALCRLFYANNWVTGTGGGISIKHPATGHIYIAPSGVQKEQIEPEDLFVLDGVDGAYLRAPAGHRPSACTPLFLACYRARGAGAVIHTHSQHAVLCTLLFDDVFRIANIEQIKALPSGRRDAAGKPLSLSFFDTLEIPIIDNTAHEEDLAPGLEAALARHPACTAVLVRRHGIYVWGPTADRAKVYNEAIDYLLELAVHMHRLGVPPDCPIGEEKRFLRR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM2A_CAEEL
Sequence: MRNFLVFSVIFIAYNSCEAANIQADNTFADPNIGEFRELLIDPKAGALFVGSEGAIFRLWAYNINDTGENVFAKKQLVLSESEESECRSTASDERLCRPSTRFLAFTNNLDSIYVCSSVGMRPEIRVLDSLSLRDQQEPRTEIGICVVDPTFNFTAVVVDSGNPEDATSVYSGIRTGMGGENHLIYRPPLTKNGKQLHASIRTIYSDNKWLNEPQFVGSFDVGQHVFFFFREIAHDNSFGERIVHSRVARVCKKDIGGRNVLRQVWTSFVKARLNCSVSANFPFYFDHIQSVKRVDKHGETYFYATFSTSETAFTSSAICMFQLSSINHLLDTGLLMEETANGQFSVTADEIPAHRPGTCSQNSHSISDTDLHFAKTHLLVSDSISGGTPILPLRDHVFTHIVVDQLPNQNVIFAFDSANRRVWKISHWKEGNEWKSNLIEEKSLKIAASRINDVALLPAEFFFVTSGAGVSQFSVARCSEQPSCALCSLDPYCSWNAVNSKCSLKTKTNEKSVGWISSSWAGRISPECSAVEKLTVKDVYLGDGLRLVGAKNGVWQKDGRSVESGQRHVVTRNGELVVLDAQLEDAGTYECLRDNIILVRARIVVHENCARPTSVAEYRSCQREWCKKADAYKAALNIWSDSNKKNVQCKANTSSAH
What is the function of this protein?
Required for the guidance of axons from neurons, including AIY interneurons, into the nerve ring.
What are the official names of this protein?
Semaphorin-2A, Sema-2a, Protein male abnormal 20.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_RHILO
Sequence: MARARSDSPLLFEIVEKPDFSFETKAMADGLWPVAGMDEAGRGPLAGPVVAAAVVLDPANIPEGLDDSKRLSHFQREALFLRILGSAQAVSMASISAEGIDGSNILKASLEAMRRALVGLSVRPKLALADGRDVPPGLPCDGRALIKGDQRSQSIAAASIVAKVMRDRMMCGCGSHHDRYGFEVHMGYATARHRTAIETHGPVARLHRVSFAPFRLGGTEVVEEESLAGLD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1615_STAAT
Sequence: MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
What are the official names of this protein?
UPF0473 protein USA300HOU_1615.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: VE1_HPV61
Sequence: MADSEGTESGDGTEAAERAGGWFLVEAVVDRTTGYQVSSDEEDNSIDTGEDLVDFIDTRRPGDGQEVPLALFVQQNAQDDAATVQALKRKYTCSPASSTCVSLVDSELSPRLDAIRIHRGQDRARRRLFEQDSGYGHTQVEIGASESQVPGDAQHEGGGESVQEAEEERGGGDGEAEATGNQETQAQEQAADILEVFKVSNLKAKLLYKFKDLFGLAFGELVRNFKSDKSICGDWVICAFGVYHAVAEAVKTLIQPICVYAHIQIQTCQWGMVILMLVRYKCGKSRETVAHSMGKLLNIPERQMLIEPPKIRSAPCALYWYRTAMGNASEVYGETPEWIVRQTVVGHAMQEAQFSLSMLVQWAYDNDITDESVLAYEYALLGNEDPNAAAFLASNCQAKYIKDAITMCKHYRRAEQAKMTMAQWITHRGRKVADTGDWKAIVKYLRYQQVEFVPFISALKLFLKGVPKKSCMVFYGPSDTGKSLFCMSLLNFLGGAVISYVNSSSHFWLSPLADTKVGLLDDATYQCWQYIDTYLRTVLDGNAISIDRKHRNLTQLKCPPLMITTNINPLEDPTFKYLHSRIVVFQFLHKCPLNSNGDPVYTLNNENWKSFFRRSWARIEGSDQQEEEEEEDEDGVTSRPFRCVPGEITRPL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PELO_THEVO
Sequence: MRLLDKDEKLGRYTLRIENLDDLWYLKNIIAPGDKISAVTFRRIEESSDMQRSREKERIPIRVTIEVEKIEFQDFENRLRILGKVTNGPEDTIGKYQSITVSEETELDVIKVWDDDSINMLKEATEQEHAAVYLAIALDDDEANVFIIHPYGIQQMGTIYSGRSGKYSESSYSETSYFSAIENAIKQFKYPIIVIGPGFAKNGLSAFLKERNYKVVAVSSSNRTDQGAIYEFISSEDGKKLISKEQISRDNEIVSAFLSSLRRGSGIYGSEEIRKYLEMGALSDLIITDKKFRSETGRELLSLARSVGTDIHIVSTSNDMGEIIEKFGGYAGILRYKVQQ
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3A_BC133
Sequence: MVSFNATAILLVLVANAFSKPLYVPEHCVGMSGTLFQACIRQTMVDTTGMYTNSAMSYDGTTIPFDRDGIVHQDHYTDTKPTPLSDVGFSV
What are the official names of this protein?
Non-structural protein 3a, ns3a, Accessory protein 3a.
Protein: APF8_GIBF5
Sequence: MSYQSILLRQVNSLCDNLEEVARDENGGLIDMAMQSDYFTFDVMSEVIFGMAYNALKDTSYRFVTGALGSSNIRIGTLVQSPLPAMCRIDKYLFPESIQGRNKFLGFIGSLLRDRSKASFAGNGNVFSFLETAKDPDGGNQLSKSEIRAECATLVAAGTDTSSSTLAATLFYLSRNSKCYSRVSEEVRNAFSSHQDIKIGPELNSCVYLRACIEETLRMSPPVGAALWREIGPGGMNIGPLTLPAGVDVGTGIYSLHHNAAYHPEPFKYLPERWLVGEGSSTSESVELARSAFAPFSRGPRSCVGKGFAYHELTLTIAHILHRFDFSATEEDFALRHGSEGPGGINEFLLHDHVTGARSGPLLQFSMRR
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the cyclic tetrapeptide apicidin F (APF) (PubMed:25058475).  The non-ribosomal peptide synthetase apf1 incorporates four different amino acids to produce apicidin F: L-phenylalanine, D-pipecolic acid (D-pip), N-methoxy-L-tryptophan and L-2-aminooctanedioic acid (PubMed:25058475).  L-Phenylalanine is the only proteinogenic amino acid directly used by apf1 (PubMed:24195442, PubMed:25058475).  The 3 other apf1 substrates are non-proteinogenic and have to be modified by other enzymes of the cluster (PubMed:25058475).  Lysine is converted to delta-1-pyrroline-5-carboxylate (P5C) which is reduced to L-pipecolic acid (L-pip) by apf3 (PubMed:25058475).  L-pip is epimerized to D-pip, probably by apf1 activity, prior to incorporation (PubMed:25058475).  L-Tryptophan is N-oxidyzed by one of the cytochrome P450 monooxygenases (apf7 or apf8), and further methylated at the hydroxy group by the O-methyltransferase apf6 to yield N-methoxy-L-tryptophan (PubMed:25058475).  The synthesis of the fourth apf1 substrate is more complex (PubMed:25058475).  The fatty acid synthase apf5 is involved in the synthesis of the octanoic acid backbone of L-2-aminooctanedioic acid by fixing one acetyl-CoA unit and three malonyl-CoA units (PubMed:25058475).  Then one of the cytochrome P450 monooxygenases (apf7 or apf8) may oxidize this backbone to 2-oxooctanoic acid (PubMed:25058475).  The aminotransferase apf4 is predicted to catalyze the exchange of the keto group with an amino group (PubMed:25058475).  The next step would be the oxidation of 2-aminooctanoic acid by one of the cytochrome P450 monooxygenases (apf7 or apf8).  The last step is the oxidation of 2-amino-8-hydroxyoctanoic acid to 2-aminooctanedioic acid is catalyzed by the FAD-dependent monooxygenase apf9 (PubMed:25058475).
What are the official names of this protein?
Cytochrome P450 monooxygenase apf8, Apicidin F synthesis protein 8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: APOA1_PONAB
Sequence: MKAAVLTLAVLFLTGSQARHFWQQDEPPQTPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSMTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELHEKLSPLGEEMRDRARAHVDALRTHLAPYTDELRQRLAARLEALKENGGARLAEYHAKASEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_CHLTR
Sequence: MEIKVLECLKRLEEVEKQISDPNIFSNPKEYSSLSKEHARLSEIKNAHESLVATKKILQDDKLALSTEKDPEIVAMLEEGVLVGEEAVERLSKQLENLLIPPDPDDDLSVIMELRAGTGGDEAALFVGDCVRMYHLYAASKGWQCEVLSTSESDLGGYKEYVMGISGASVKRFLQYEAGTHRVQRVPETETQGRVHTSAVTVAVLPEPAEDDEEVFIDEKDLRIDTFRSSGAGGQHVNVTDSAVRITHIPSGVVVTCQDERSQHKNKAKAMRVLKARIRDAEVQKRAQEASAMRSAQVGSGDRSERIRTYNFPQNRVTDHRIGLTLYNLDRVMEGELDMITTALVTHVHRQLFGHEETA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS10_ASPNC
Sequence: MIFRWLLLVSCLLVALIPQQSSAKKSDQPKVTATKLEHEPFSLFYFEDSETVLMSLKNGEFKQSFDGGEEWEDVASSEDGRVTQPVVFIRQHPFDKNKAYALGVDGHHLVTTDQAKTWRSFDIGDQPALQHPPLVFHGWDSSKVIYQSEECAGFFCITVRLLRESAAGCSWAVGHPHFAEDMDLNQELKDRSLCVVPGLKVPFGHANRLVYSDDYFVSNIEGTEVNLHEGRPVSGVISTAAVKKFIVAAVKSKGTEELALFVTTDTNTWHRAEFDGHRIEQDAYTMLESTNYSLQVDVLTSPSSNMGVLFTSNSNGTFFSRNIEHTNRDMEGTVDFEKIAGIQGIVMVNTVKNPKEVKSGQAKKVISRISFDDGRSFQPLKVGDKNLHLHSVTTFANIGRVFSSPAPGLVMGIGNTGDHLQKYSDGDLYISDDAGVTWRHALDGPHKYEFGDQGAVVMAISDKGKSNKISFSLDHGKEWGSVEIEHKIYPTMVTTTPDSTSLRFLLVGKQNEESGFIVYSIDFKGLHERKCEEDDFEKWPARLDENGEPDCLMGHKQFFRRRKANADCFVDEEFKDPQPIMEPCKCTAEDFECEFKGSEDGKSCIPALLPVPPEGCKNPDDTFMGPSGWRLIPGDTCIRDGGKNLDHDVEWRCKDAGNVPTSGEISVEKQYFDARQFSAYYYLERQSSSSGNDETIVMLTSERALYVSHDHGKTWKQPLKGEAINRIVPHPYNSDGAFLLTDGAEGFWTVDRGQSFKPFDAPAPPTEERLPTLTFHPQYQDWLIWTGAVDCGSGDCHSNAYISKNRGDNWELLQRYVQKCEFESREGRKDSTNLIFCEQFENENRNNRLQLVSSKNWFSDSTVHFRDVINYATMSEFIVVASRDTEKPDSLVASSSVDGETFAEAKFPPNVNVPVQTAYTVLESSTHAVFLHVTVSNSEGAEYGSIIKSNSNGTSYVLSLGAVNRNFRGYVDFEKMQGIEGVAVANVVSNVNKLSDGEPKKLRTMITHNDGGQWTLLSPPNKDAEGKDFGCSVEGEGVPGCSLHLHGYTERRDERDTFSSSSAIGLMLGVGNVGDHLGGEDEADTFITRDAGFTWKSVKKGRYIWEFGDAGSLIVIVPESKPTKTLYYSLDEGDTWLDFVFSDVEMQIDDISTVPSDTSKSFLLWGKELKSDYQDKLATVSVDFSGLRSSSCKLDENSAESHDYYLWEPKHPFQSDNCLFGHVEQYHRKKPSAQCWNDWREPHVHSIGENCPCTRADFECDYNYEPQSDGSCALVQGLAPPDAMAVCREDPEAYQYWEPSGYRRLPQSTCQGGREMDHIVSKPCPNREEEYKKKHGISGAGLFFAIVIPIAVASAVGYYGYTRWDGKFGQIRLGENVGTSQGLLSRDSLLITIPVTIIAGAVAVIKALPLLATSLWRSASGYVRLGRNRGYSRPYASRGSFAARRGDYTGVVDDEDELLGVEDLEADEEEEL
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: ACKA_YERPY
Sequence: MSSKLVLVLNCGSSSLKFAIIDATNGEEHISGLAECFHLPEARIKWKVDGGKQEAALGAGAAHSEALNFIVNTILAQKPALSAQLTAIGHRIVHGGEKFTSSVIVTDDVIQGIKDSIPFAPLHNPAHLIGIAEALKSFPNLADKNVAVFDTAFHQTMPEESYLYALPYSLYKDHGIRRYGAHGTSHFYVSQEAAKILNKPLEELNVITCHLGNGGSVTAVRNGKCVDTSMGLTPLEGLVMGTRSGDLDPAIIFHLHDAMGMSVDQINTLLTKESGLLGLTEVTSDCRYVEDNYATKADAKRAMDVFCHRLAKYIGSYTALMDGRLDAVVFTGGIGENAAMVRELTLDKLGLLGFEIDHERNMAARFGKSGTITKDSSRLALVIPTNEELVIAQDAARLTA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_BACAA
Sequence: MANAYKQAGVDIEAGYEAVSRMKKHVQTTMRKEVLGGLGGFGGMFDLSKFALEEPVLVSGTDGVGTKLMLAFMADKHDTIGIDAVAMCVNDIVVQGAEPLFFLDYIACGKAEPSKIENIVKGISEGCRQAGCALIGGETAEMPGMYSTEEYDLAGFTVGIVDKKKIVTGEKIEAGHVLIGLASSGIHSNGYSLVRKVLLEDGELSLDRIYGRLELPLGEELLKPTKIYVKPILELLKNHEVYGMAHITGGGFIENIPRMLPEGIGAEIELGSWKIQPIFSLLQEVGKLEEKEMFNIFNMGIGMVVAVKEEDAKDIVRLLEEQGETARIIGRTVQGAGVTFNGGKAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCA_BACSU
Sequence: MKKALICIDYTNDFVASDGKLTCGEPGRMIEEAIVNLTKEFITNGDYVVLAVDSHDEGDQYHPETRLFPPHNIKGTEGKDLYGKLLPLYQKHEHEPNVYYMEKTRYSAFAGTDLELKLRERQIGELHLAGVCTDICVLHTAVDAYNKGFRIVVHKQAVASFNQEGHAWALSHFANSIGAQVAE
What are the official names of this protein?
Uncharacterized isochorismatase family protein PncA.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: EI3G2_DROSE
Sequence: MKSFVTSWADEVDADYVDGLPPSNEYIKGDYKYVTEYKFNDDGKKVKVVRTFKIEKQIVPKAVARRRNWVKFGDSRSDKPGPNSQTTMASEEILMQFIGSKEFDQTHETQLDPGKNIAKCRICNGEHWSVNCPYKGTSMDSKTVMETKANAAAAAAISDPSKTGKYVPPFMKDGGGISGSKNWGRGRDRDDSSAVRISNLSESMTETDLEELVKKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-2, Eukaryotic translation initiation factor 3 RNA-binding subunit 2, eIF-3 RNA-binding subunit 2, Eukaryotic translation initiation factor 3 subunit 4-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_STRA3
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQNISDAEEMIKDASGDAELEEMAKEELKESKAAKEEYEERLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYEIDQKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTQKLEALNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O267_CONVE
Sequence: MKLTILFLVAAVLMSTQALIQHDGEKSQKAKMKFLTARTLSAKKRDVDCVGWSSYCGPWNNPPCCSWYTCDYYCKL
What are the official names of this protein?
Conotoxin VnMEKL-012.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YNL39_YEAST
Sequence: MESIILSIAIFIGVLLGTSVGTFSGSGISAGVGASSGSGISAGVGASSGSSTSVGVGTFGGSSTSVGVGTFGGSSTSVGVGTFSGSRTSPDVDAGSGSSTSPDVGAGSGSSISAGVGTFSGSRTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGISTTMNARVAVLITAAILSAPVTAIALLEARR
What are the official names of this protein?
Putative uncharacterized protein YNL339W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.