PharMolix/UniProtQA huggingface dataset:
Protein: LIGC_SPHSK
Sequence: MRIALAGAGAFGEKHLDGLKNIDGVEIVSIISRKAEQAAEVAAKYGAKHSGTDLSEALARDDVDAVILCTPTQMHAEQAIACMNAGKHVQVEIPLADSWADAEAVMKKSQETGLVCMVGHTRRFNPSHQYIHNKIVAGELAIQQMDVQTYFFRRKNMNAKGEPRSWTDHLLWHHAAHTVDLFAYQAGKIVQANAVQGPIHPELGIAMDMSIQLKSETGAICTLSLSFNNDGPLGTFFRYICDNGTWIARYDDLVTGKEEPVDVSKVDVSMNGIELQDREFIAAIREGREPNSSVARVLDCYRVLGELEVQLEKQG
What is the function of this protein?
Involved in the degradation of protocatechuate (PCA) via the PCA 4,5-cleavage pathway.  Catalyzes the oxidation of the hemiacetal form of 4-carboxy-2-hydroxymuconate-6-semialdehyde (CHMS) to produce 2-pyrone-4,6-dicarboxylate (PDC).  LigC has 10-times-higher affinity to NADP than to NAD.
What are the official names of this protein?
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase, CHMS dehydrogenase, 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SUCC_NEIMA
Sequence: MNLHEYQAKELLASYGLPVQGGILAHNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREEAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRVTFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQAREVAFQLGLKDKQINEFVKLMTGAYKAFVENDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIFGGIVRCDMIAEAIVAAVKEINVDVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RSMC_ECO24
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANCVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_CHLFF
Sequence: MTMLVVAIGNPGRQYTWTRHNIGFLCADRLLQEFSGVHFKETPKLFSDIAKVESSQGTVIFIKPRTYVNLSGKAVLAVKEYYNIATDRILVLADDVNQPFGKVRLRQSAGGGGHKGIKSITQSLGSNDYWQLRLGVGRPQREDVELSDFVLGQFTEEEQIGIQSLFIEAWALFSQWCSGTQTA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_YERE8
Sequence: MLRILLSNDDGITAPGIQTLAAALREFAQVQIVAPDRNRSGSSNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGQQHYATAAAVTCRILRALQHKPLRTGKILNINIPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKFDVAEDTDFAAVEQGYVSITPLQVDLTAYGAQDVVENWLASMAD
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB4T_TITCO
Sequence: MQIKHLITLFFLVLIGADQCSAFFSLIPSLIGGLVFAIKGRKKREVSPQIDQYRNFQKREAELEELLDRLPMY
What is the function of this protein?
Antibacterial peptide.
What are the official names of this protein?
Putative antimicrobial peptide clone 5.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CZIB_HUMAN
Sequence: MGKIALQLKATLENITNLRPVGEDFRWYLKMKCGNCGEISDKWQYIRLMDSVALKGGRGSASMVQKCKLCARENSIEILSSTIKPYNAEDNENFKTIVEFECRGLEPVDFQPQAGFAAEGVESGTAFSDINLQEKDWTDYDEKAQESVGIYEVTHQFVKC
What are the official names of this protein?
CXXC motif containing zinc binding protein, UPF0587 protein C1orf123.
What is the protein family that this protein belongs to?
Belongs to the UPF0587 family.
Protein: EFG_ECO55
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STAAR
Sequence: MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y1599_LISMF
Sequence: MKISFHGQSCIKIITGDTTILVDPFISGNDKCDLKAEEQMPDFIVLSHGHDDHVGDTVEIAKNSGATVICNADLASFLAVEDGLENIAPMHIGGKRQFSFGQVKLTQAFHGSQTVRDGRIVNLGFPTGIVFTIEDKNIYFAGDTGLFSDMKLIGELNPLDVAFLPIGDNFTMGPEDAAIAARFLQAKLVVPMHYNTFPLIAQDPHKFVASLDEGITGKVLEIGEGIEI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase LMOf2365_1599.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: COF_YERPN
Sequence: MYRLAAFDMDGTLLMRDHKIGSITLNALHQLADAGVTLTFATGRHYLDMKGILSHSGLNGYLITGNGTRVCDAEGNPLYGMDLPAELVEFVLRTPWQTNASIHLFRDDGWFTDRNDPDLLIAHTTSGFHFQLTEWDELPLTGNHKFCFIASHQELVELKAQLEQQMGGEADFCFSATDCLEVLPRGCNKGVALEKLSHHLDLTLADCMAFGDAMNDKEMLSRVGRGLVMGNALPQLKQELPQLQIIGRCEQQGVAHYLHHWLSSPHLTYSPEF
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: YBEY_PSEA7
Sequence: MPLELDLQVASDAADLPSEAQFRAWCELALRQRAESELTIRLVDEAEGLELNSTYRHKDYATNVLSFPADVPEEFLDIPLLGDLVICAPVVAREAREQHKPLQAHWAHLVIHGCLHLLGYDHIDDAEAEEMETLERELLAELGHPDPYACDDEEPPSKEK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_LACE2
Sequence: MAGINQKNIRNFCIIAHIDHGKSTLADRIIEKTGLLTSREMQEQILDNMDLERERGITIKAQTVRTVYKASDGQEYIFNLIDTPGHVDFNYEVSRALAACDGAILVVDAAQGIEAQTLANVYLALDHDLDVFPVINKIDLPSAEPERVIEEIEDIIGIEAQDAPLISAKNGINIEEVLEQIVTKIPAPSGDASAPLSALIFDSLYDAYKGVIIFVRIKEGTVKKGTKIRMMATGAVEEVVEVGYFGAGRFIPCDELTAGMVGYITASIKNVRDTRVGDTVTDNDRPCEQPLPGYKKVNPMVYCGLYPADGAKYQDLRDALEKLQLNDAALQFEPETSIALGFGFRCGFLGLLHLEIIQERLEREYNLDLVTTAPGVIYKVHKTNGDVIDLTNPSNMPDPSEIDYMEEPMVSAEIMVTTEFVGPIMKLCQERRGIYNGMEYIEQTRALLKYDLPLNEIIYDFFDALKSRSRGYASFDYEMKGYERSKLVKLDILINKEEVDALSFIVFAGNAEERGRKMCEKLKEEIPRQQFEIPIQAAIGSKVIARETVKALRKDVLAKCYGGDISRKKKLLEKQKEGKKRMRQIGNVEIPQKAFMSVLKLDDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LYZL1_MOUSE
Sequence: MKSVGVFALIISFSIVAESKIYTRCKLAKIFAKAGLDNYGGFALGNWLCMAYYESHYNTTAENVLEDGSTDYGIFQINSFTWCRNARKHQKNHCHVACSALITDDLTDAILCAKKIVKETQGMNYWQGWKKNCENKDMSEWKRGCEVS
What are the official names of this protein?
Lysozyme-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAN4_ARATH
Sequence: MMMLESRNSMRASNSVPDLSLQISLPNYHAGKPLHGGDRSSTSSDSGSSLSDLSHENNFFNKPLLSLGFDHHHQRRSNMFQPQIYGRDFKRSSSSMVGLKRSIRAPRMRWTSTLHAHFVHAVQLLGGHERATPKSVLELMNVKDLTLAHVKSHLQMYRTVKCTDKGSPGEGKVEKEAEQRIEDNNNNEEADEGTDTNSPNSSSVQKTQRASWSSTKEVSRSISTQAYSHLGTTHHTKDNEEKEDTNIHLNLDFTLGRPSWGMEYAEPSSDLTLLKC
What is the function of this protein?
Probable transcription factor that regulates carpel integuments formation.  Required for the specification of polarity in the ovule inner integument.  Modulates the content of flavonols and proanthocyanidin in seeds.
What are the official names of this protein?
Probable transcription factor KAN4, Protein ABERRANT TESTA SHAPE, Protein KANADI 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSHA_STAA3
Sequence: MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIEKVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALKKGPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQTMLFSATMPKAIQALVQQFMKSPKIIKTMNNEMSDPQIEEFYTIVKELEKFDTFTNFLDVHQPELAIVFGRTKRRVDELTSALISKGYKAEGLHGDITQAKRLEVLKKFKNDQINILVATDVAARGLDISGVSHVYNFDIPQDTESYTHRIGRTGRAGKEGIAVTFVNPIEMDYIRQIEDANGRKMSALRPPHRKEVLQAREDDIKEKVENWMSKESESRLKRISTELLNEYNDVDLVAALLQELVEANDEVEVQLTFEKPLSRKGRNGKPSGSRNRNSKRGNPKFDSKSKRSKGYSSKKKSTKKFDRKEKSSGGSRPMKGRTFADHQK
What is the function of this protein?
DEAD-box RNA helicase possibly involved in RNA degradation.  Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CALFO
Sequence: MALNLRKNHPLMKIINDSLIDLPTPSNISVWWNFGSLLGICLVTQIVTGLLLSMHYTADTSLAFASVSHMCRNVQFGWLIRNLHANGASLFFICIYLHIGRGLYYGSYLNKETWNIGVILLLTLMATVFVGYVLPWGQMSSWGATVITNLFSAIPYIGQTLVEWLWGGFSVDNPTLTRFFAFHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDLLGFVLMLIVLVTLALFNPYMLGDPENFTPDKPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPLLHTSKQRSMTFRPLSQILWWTLVADLLILTWVGSQPVEHPFIIIGQLASFAYFTIILILFPIASALENKMLNL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYCC_MICEH
Sequence: MTEVDLKALLADVDGDVATELASKPEVIDKGHELDISTLPIQARKWHKLRDAVAVVADLKSSTQLGLNKHAASTASIYEAATGGVVQIFDEFDANFVAIQGDGAFALFWGDKRRQRAVCAGITIKTFSFKHLVPRLEKKWDGLPETGLKVGLGSSPLLVKRVGVPRTEHQEPVWAGRAVNYAAKAAQQADRHEMVVTGTIWDWVSDNDFLAVTCSCSNPNPDLWSNITIEKIPDGDGDREGKRLTSSWCDVHGPEYCAAVLEGKKRRADVTTQRTSALAAEMKSWVRNKAAQDRKNRLARYQGLH
What is the function of this protein?
The pyrimidine cyclase gene of a two-gene Pycsar system, generates cyclic UMP (cUMP) from UTP as well as cGMP from GTP to a lesser extent, has little to no activity on ATP or CTP (PubMed:34644530).  Expression of this and adjacent effector MePycTM (AC A0A1C5G2D0) probably confers resistance to bacteriophage.  The genes are probably only expressed in response to bacteriophage infection (Probable).
What are the official names of this protein?
Uridylate cyclase, Cyclic UMP synthase, cUMP synthase, MePycC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Pyrimidine cyclase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTP1_SCHPO
Sequence: MDANQKLLDFAKLLNQKNDSRPVIEKLKDNISGDLLNYFLNLLEEISKLDTDQPLSVTSLRCLQLFVHLTFLLGVYTQLPKEMLSQAKIKALPIYTPKKNLVQIYNILLPLLLTPSLLQGPLNLHYADLLLLHLYLLNCHEQGSLIEEPRPLFLDPSWKEKVTSIMSPQMVDPSKMISSCLSLLQPNVDNWLQDKLKHYLTTCLCRETGVQGFLKVYMQAQPNSIERARQAAHLISSVPKDISPQKYFSCILPQVWSLFSTQPRLASQLIIAVTNTHCDIVTSFLLKKLQILEAPKVIDLSPFENALDVLQVLVYIQNDDIIRICESCVPSLLHLQENTTLRSKVQDILLRIISVCGTKSLLRNLTNAKHLRIFCERLTKSQLAMFLPNLLEIWVQQPPDKRLELLELVQYALSNVDSDEIPSNVMLSVCTNLINEVASQNKYSSTEISQITTNREVEEENEEILLVLLNIISSVIGRNAELDLENPISSLLPALEQLSNYSNREISDLAKDVYKTLIQSKDDYSLALSYTQSDLVPVRGQGVYMLRKLIEKKDDRINPVRVLHVLINLLRDENSYVHLNVISAVVSLCDKYDDSLIRLLKEYTNTNKFTVDETLLIGQAIYQTMERQGELVAKFYGQIEQTCLSMLNNENTDIKISSLNIARLLCQMTSSDAFIESAKNILILEMGSDKQFLRRAAVQLLDSCKHLPDSVITTLSYVGSHDKDDFIKESCLNILANQADAAKYYLQ
What is the function of this protein?
Required for the cytoplasmic assembly and the nuclear import of RNA polymerase II.
What are the official names of this protein?
RNA polymerase II assembly factor rtp1.
What is the protein family that this protein belongs to?
Belongs to the Tango6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AROE_YERPN
Sequence: MDQKFAVFGNPISHSKSPRIHTLFSEQTGIEHRYGKVLAPSEAFENTLVSFFADGAQGANITTPFKERAYDQCDELTDRASLAGAVNTIKRLEDGRLLGDNTDGIGLLSDLERQNLIRTTDHILLVGAGGAARGVILPLLSYGCTVVVTNRTHTRAQQLAKVFNHIGDIDVCEMSELAGQRFDLVINATASGLHGEVPNLPAAILTSQTRCYDMFYQAGTTPFLAWAQRLGLADYADGLGMLVGQAAHAFKLWHGVMPEITPVLAQLRSELGK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS20_MYCTA
Sequence: MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: AT221_SCLS1
Sequence: MEDGGAGLRAPRYPAEDTSPTTDRELRGFFCYGLAAEVFAVCAVGSFLPVTLEQLAREQGVLFIDKVTPCTAKNATVIANATVNALMSRAEGSDTHQCIINVFGAELTTASFAMYTFSASVFMQALALVSVSSVADHGTWRKKLLAGFGLTGSVSAMLFLLVVPQIFVVGSFLTVICVVCLGCSFVILNSYLPLLVLNHPVVQSDEDHPTASSSIPLQPISPQRSSRKSEESLHQVNRKEVDIGSKADSSDLQLSTKISSKGVGIGYMAAVSVQVICILILYIMNKTGVSSTLPLRTVLFFVGSWWLTFTIPSVMWLRDRPGPPLPTALYEGRAFVRTCMSYTIFAWKSLWKTVKVAVKLRQVLLFLIAWFLLSDAVATISATAILFARTELQMGTVAVALLSIIATSSGIIGATVWPIISKRFTLKTNHIIVCCLLLLELVPLYGLLGFLPFVQAWGVGGLQKWYEIYPLGIIHGMVMGGLSSYCRSFYGLLIPPGSEAAFYALFAITDKGSSAVGPAIVGKIVDATGQIRPAFGFLAVLIALPIPLIWMVDVEKGQEDAIRMAGLMKTTDDGHEDFESFEGSSDGHEAEGLMRDHD
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-1.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: HSP60_SCHPO
Sequence: MVSFLSSSVSRLPLRIAGRRIPGRFAVPQVRTYAKDLKFGVDARASLLTGVDTLARAVSVTLGPKGRNVLIDQPFGSPKITKDGVTVARSVSLKDKFENLGARLVQDVASKTNEVAGDGTTTATVLTRAIFSETVRNVAAGCNPMDLRRGIQLAVDNVVEFLQANKRDITTSEEISQVATISANGDTHIGELLAKAMERVGKEGVITVKEGRTISDELEVTEGMKFDRGYISPYFITDVKSQKVEFENPLILLSEKKVSAVQDILPSLELAAQQRRPLVIIAEDVDGEALAACILNKLRGQLQVVAIKAPGFGDNRRNMLGDLAVLTDSAVFNDEIDVSIEKAQPHHLGSCGSVTVTKEDTIIMKGAGDHVKVNDRCEQIRGVMADPNLTEYEKEKLQERLAKLSGGIAVIKVGGSSEVEVNEKKDRIVDALNAVKAAVSEGVLPGAGTSFVKASLRLGDIPTNNFDQKLGVEIVRKAITRPAQTILENAGLEGNLIVGKLKELYGKEFNIGYDIAKDRFVDLNEIGVLDPLKVVRTGLVDASGVASLMGTTECAIVDAPEESKAPAGPPGMGGMGGMPGMM
What is the function of this protein?
May participate in assembly and/or disassembly of proteins imported into the mitochondrion.  HSP60 are ATPases and have affinity for unfolded proteins.
What are the official names of this protein?
Heat shock protein 60, mitochondrial, HSP60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GTHB2_ONCKE
Sequence: MLGLHVGTLISLFLCILLEPVEGSLMQPCQPINQTVSLEKEGCPTCLVIQTPICSGHCVTKEPVFKSPFSTVYQHVCTYRDVRYETIRLPDCPPWVDPHVTYPVALSCDCSLCNMDTSDCTIESLQPDFCITQRVLTDGDMW
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-2, GTH-II-beta, Gonadotropin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: THII_STRP8
Sequence: MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVRSDRDRTHVYLNGTDYQPVVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRDGLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAYISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPGALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIREQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTFDISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIVNDEVENLIDALL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHA_KLEP3
Sequence: MALPMMIDCDPGHDDAIAMVLALASPELEVKAVTASAGNQTPEKTLRNVLRMLTLLNRPDIPVAGGAWKPLMRDLIIADNVHGESGLDGPSLPEPTFAPQNCTAVELMARVLRESQEPVTLVATGPQTNVALLLASHPELHAKIARIVIMGGAMGLGNWQPAAEFNIFVDPQAAEMVFQSGIPVVMAGLDVTHKAQILPADIERFRQIGNPVSTIVAELLDFFMAYHKDEKWGFDGAPLHDPCTIAWLLKPEIFTTIERWVGVETEGKYTQGMTVVDYYHLTGNRPNTTLMLDVDREAFVDLLAQRLAFYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: RS15_ECO24
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NEP_I56A2
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRNSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.