PharMolix/UniProtQA huggingface dataset:
Protein: PANB_RALSO
Sequence: MSSYLQESTRKAVTVTSLQGMRAAGERIAMLTAYDASFAALMERSGVDVVLVGDSLGNVVQGQKTTLPVTLDHIVYHTECVARGTTKALLMSDLPFGTYGTPEQAFHSAVRVMQAGAQMVKLEGGEWLAPTLRFLVERSIPVCAHIGLTPQSVHAFGGFKVQGRGDEAAAQLKADALAVQDAGAQMVLMEAIPATLAGEVTRLLAVPTIGIGAGPECSGQVLVMHDMLGVFPGHRPKFVRNFMDGLTTIDAAVTAYVTAVKDGTFPGPEHSFTA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LACDA
Sequence: MAKKVINVVKLQIPAGAATPAPPVGPALGQAGINIVGFTKDFNARTADQKGMIIPVVITVYEDRSFDFVTKTPPAPVLLKQAAGIQKASGEPNKNKVGSVTTAQVKEIAETKMKDLNAASIEAAMRMVEGTARSMGIEVKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PYRC_SYNAS
Sequence: MKILLKGGRVIDPAQNLDGQMDLLLENGKIAAIAEAVGSVPEDTRLLDLKGMILLPGLVDMHTHLREPGYEYKETIRSGSEAAAVGGFTSIACMPNTLPVNDNRTVTEYILKRAKECDTVHVYPVAAVSRNSEGKILAEFGDLKEAGAIAFSDDGKPVMNSILMRRALEYASSLDRIIISHCEDLNLSAGGLMNEGKISTELGLPGIPTLAEDVMVARDLLLAEFSGAALHIAHVSSAGAVRMIRDAKKRGVRVTAETTPHYFTLTDEAVTNFNTNTKVSPPLRSREDLQAVREGLRDGTLDAIVTDHAPHALTDKEVEFEYAANGISGLETALALSLTLVDDGLLTLSELVRKMSVNPAKILNIPKGTLRPGADADITVLNPGKTWVVDPSNWRSQGKNTPFFGWTLKGKVIMTLVQGRIVYQED
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: Y6200_HAEIE
Sequence: MEIVNKQSFQDVLEYVRMYRLKNRIKRDMEDNNRKIRDNQKRILLLDNLNQYIRDDMTIAEVRGIIESMRDDYESRVDDYTIRNAELSKQRREASTKMKEQKKAHAELLKNAEK
What are the official names of this protein?
UPF0265 protein CGSHiEE_06200.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: RL3_METS4
Sequence: MRSGVIAQKVGMTRVFTDAGEHVPVTVLKVDQCQVVAHRTVEKNGYVALQVGVGKAKVKNVSKAERGRFAIAKVEPKRKLAEFRVTEDALIPVGAEITADHFIPGQFVDVTGTTTGKGFAGGMKRWNFGGLRATHGVSISHRSIGSTGGRQDPGKTFKNKKMPGHLGVERVTTQNLRVVRTDPERGLILVEGAVPGVAGGWIQIRDAVKRKLPAEAPMPGKFRELADGAAPAVDAAPEAPAVEENA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YIHI_ECODH
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: ISPF_PSEA8
Sequence: MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVAVDQVNVKATTTERLGFTGREEGIAVHAVALLMAR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SAC2_MOUSE
Sequence: MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQELELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTNIKSNVSAPNKKKVKESKEKEKLERRLLEELLKMFMDSESFYYSLTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQALTEIGTPDVDFWIIPIIQGFVQIEELVVNYNESSDDDKSSPETPPQDSTCVDDIHPRFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHHHTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQAGREKIIGDAYLKQVLLFNNPKLTYVSFDFHEHCRGMKFENVQTLTDAIHDIIIDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRTYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQGVPVTEDLYSIFTKEKEHEALHKESQRSHQELISQLLQSYMQLLLPGDEKFHGGWALVDCDPSLTDAAHRDVEVLLLLSNAAYYVAYYDDEVDKVNQYQRLGLEDLERIEIGPEPTLFGKPKFSCMRLHYRCKEAGGYFHTLRAVPRSPEEDGKDTLQCIAEMLQITKQAMGLDVPIIEKKLERKSSKPHEDIIGIRSQNQGSLAQGKSFLMSKFSSLNQKVKQTKSNVNIGNLRKLGNFTKPEMKVNFLKPNLKVNLWKSDSSLETMENPGVMGNKVQGESDGDISSDNDSYHSDEFLTNSKSEEDKQLANSLESVGPIDYILPSCGIIVSAPRLGSRSQSASSIDVSTHAPSEAAAGPGSELGKGLESPLKKSPSADSIHTRTGFTKPMDVYCQRFVQDAQNKMNDLSEIRSVAQKSEEGSHKTNRVSNEETQSEPMGQTPPRPSQLNVSCSVAGPPFLSVEPVHSVLSQKTPSSGSSLLELEAGLCVTPSSESSSSRAVSPFAKIRSSMVQVANITQAGLTHGINLAVAKVQKSPAEPEAVNEIQQNELKNMFTQCQTRIIQI
What is the function of this protein?
Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate.  May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869668, PubMed:25869669).  Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (By similarity).  Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895).  Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (By similarity).  Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (PubMed:19875726).  May play a role as negative regulator of axon regeneration after central nervous system injuries (PubMed:26203138).
What are the official names of this protein?
Phosphatidylinositide phosphatase SAC2, Inositol polyphosphate 5-phosphatase F, Sac domain-containing inositol phosphatase 2, Sac domain-containing phosphoinositide 4-phosphatase 2, hSAC2.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Early endosome. Recycling endosome. Note=Also found on macropinosomes.
Protein: TYPH_PECAS
Sequence: MFLIQEIIRKKRDGKTLSEEEIRFFINGIRDNTVSEGQIAALAMTIYFHDMSMDERVALTLAMRDSGTVLNWKSLNLNGPLVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGLDIFPNDDHFRRIIQQVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEQLAQAIVGVANNAGCRTSALLTDMNQVLASSAGNALEVREAVRFLTGESRNPRLYDVTMALCGEMLLAGGLASSADDAHSRLQAVLDNGKAADVFGRMVAAQRGPGDFVEHYDRYLPVATLSKPVFATREGVVTAMDTRALGMAVVSLGGGRRQASDTIDYSVGLDSMISLGERVDAQRPLAVIHANTEAQWQQAANEVRAAIQLGDTAPEKTPMVYRRVSAEA
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: APT_SINMW
Sequence: MTALQSDLISAIRSIPDYPKPGVMFRDITTLLGNPRAFRRAIDELVHPYAGTKVDKVAGIEARGFILGGAIAHQLSAGFIPIRKRGKLPHDTVRIAYSLEYGVDEMEMHRDAVVPGDKVILVDDLIATGGTAEGAAKLLQQMGAEIVAACFIIDLPELGGRRKLEALGVNVRTLIEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_LISW6
Sequence: MTLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSESLPIENDRMKQMLTERQFPEEYTQSLFNVGETSSNLEVSSQYTAFPIENSDLFTKGLTTIVPIVGGGERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAEEIEEEARSRAVVQMAISSLSYSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGTFIRVLNDKFLVELEKLKNN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABHDD_HUMAN
Sequence: MEKSWMLWNFVERWLIALASWSWALCRISLLPLIVTFHLYGGIILLLLIFISIAGILYKFQDVLLYFPEQPSSSRLYVPMPTGIPHENIFIRTKDGIRLNLILIRYTGDNSPYSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLLLVDYRGYGKSEGEASEEGLYLDSEAVLDYVMTRPDLDKTKIFLFGRSLGGAVAIHLASENSHRISAIMVENTFLSIPHMASTLFSFFPMRYLPLWCYKNKFLSYRKISQCRMPSLFISGLSDQLIPPVMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKEVVKSHSPEEMAKTSSNVTII
What are the official names of this protein?
Protein ABHD13, Alpha/beta hydrolase domain-containing protein 13, Abhydrolase domain-containing protein 13.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: YPFN_SALA4
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEDDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NFYBA_ARATH
Sequence: MAESQTGGGGGGSHESGGDQSPRSLNVREQDRFLPIANISRIMKRGLPLNGKIAKDAKETMQECVSEFISFVTSEASDKCQREKRKTINGDDLLWAMATLGFEDYIDPLKVYLMRYREMEGDTKGSGKGGESSAKRDGQPSQVSQFSQVPQQGSFSQGPYGNSQGSNMMVQMPGTE
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.  The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
What are the official names of this protein?
Nuclear transcription factor Y subunit B-10, AtNF-YB-10.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GTHB2_CYPCA
Sequence: MGTPVKILVVRNHILFSVVVLLAVAQSSYLPPCEPVNETVAVEKEGCPKCLVLQTTICSGHCLTKEPVYKSPFSTVYQHVCTYRDVRYETVRLPDCPPGVDPHITYPVALSCDCSLCTMDTSDCTIESLQPDFCMSQREDFLVY
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-2, GTH-II-beta, Gonadotropin beta-II chain, Luteinizing hormone-like GTH.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLYX_ECODH
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RL23_MYCTA
Sequence: MATLADPRDIILAPVISEKSYGLLDDNVYTFLVRPDSNKTQIKIAVEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSRPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EFTS_ANAPZ
Sequence: MKIDVEVIKELRQITGAGIGDCKEALESCSGDMDKAREYLREKGLSKAYKKSHRDVADGLVAVFAEGDVGAILKLGSETDFVARNEKFRSLALGLVRGLYGYGVEDLEGFSASSYDGSRVADEIVAAAAVLGENVVLSGVGFVKLSGPGVIGSYVHGMVSEGLGKAAALVVLEGGPHSDELASFAKQLAMHIVAAKPEALSIDTLSSDVVDRERELVARQVEALGKPDSVAQKIIEGRMQKFFEEMVLLEQVFVMDGQTKIRDLLVQKGQSLKHEIRIAAYRLFAIA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELBB_SHIFL
Sequence: MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQQVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLSNFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTAEVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE
What is the function of this protein?
Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.  However, this apparent glyoxalase activity may reflect a deglycase activity, which could be the primary function of this protein like other DJ-1 superfamily members such as PARK7, YajL, YhbO and HchA.  Is not able to use methylglyoxal as substrate.
What are the official names of this protein?
Glyoxalase ElbB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RSMH_STRGC
Sequence: MTNEFHHVTVLLHETIDYLDVKPDGVYVDATLGGAGHSEYLLSKLSPKGHLYAFDQDATAIEHAKKRLAPYIEKGMVTFVQDNFRHLKLQLEKLGVDEIDGICYDLGVSSPQLDERERGFSYKQDAPLDMRMNRHADFSAYQVVNDYDYHDLVRIFFKYGEDKFSKQIARKIEQARQIKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAIDLLAVDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPFIPDDLKPKLELISRKPILPSAEELELNNRAHSAKLRVAKKVHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_CAMJD
Sequence: MNLKILGIDPGSKNCGYAIIERSKGKNILIEAGLIKIKPSTLQYQITELCEGLDLIFKNHSFDEVAIEDIFFAYNPKTVLKLAQFRGALSLKILQIHGDFAEYTPLQVKKAVTGKAKATKEQVAFMVKRLLGLSKDIKPLDITDAIAIALTHAANLRTRV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: COX1_CANLF
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFAHWFPLFSGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVMLMIFMIWEAFASKREVAMVELTTTNIEWLHGCPPPYHTFEEPTYVIQK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UNG_BORBZ
Sequence: MKVKIEESWKEVLNNEFNKEYFKKLVKFIKHEYKTKNGKIFPPPKLIFNAFNSLPFKDIKVVIIGQDPYHGKNQANGLAFSVDSKIKIPPSLQNIFKEIEKSLKIKTIPNGDLKRWAIQGVFLINTILTVEEGKPSSHKAIGWEIFTDEVIKIISKNLKNIVFMLWGNLARSKKGLIDPTKHLILETSHPSPYSANNGFLGSNHFSSALDYLKKHNKNIINFQ
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_SALG2
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLHDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQAFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CPNE6_PONAB
Sequence: MSDPEMGWVPEPPTMTLGASRVELRVSCHGLLDRDTLTKPHPCVLLKLYSDEQWVEVERTEVLRSCSSPVFSRVLALEYFFEEKQPLQFHVFDAEDGATSPRNDTFLGSTECTLGQIVSQTKVTKPLLLKNGKTAGKSTITIVAEEVSGTNDYVQLTFRAYKLDNKDPFSKSDPFMEIYKTNEDQSDQLVWRTEVVKNNLNPSWEPFRLSLHSLCSCDVHRPLKFLVYDYDSSGKHDFIGEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKNYKSSGTVVLAQCTVEKVHTFLDYIMGGCQISFTVAIDFTASNGDPRSSQSLHCLSPRQPNHYLQALRAVGGICQDYDSDKRFPAFGFGARIPPNFEVSHDFAINFDPENPECEEISGVIASYRRCLPQIQLYGPTNVAPIINRVAEPAQREQSTGQATKYSVLLVLTDGVVSDMAETRTAIVRASRLPMSIIIVGVGNADFSDMRLLDGDDGPLRCPRGVPAARDIVQFVPFRDFKDAAPSALAKRVLAEVPRQVVEYYASQGISPGAPRPCTLATTPSPSP
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes.  Binds phospholipid membranes in a calcium-dependent manner (By similarity).  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Copine-6, Copine VI.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Perikaryon. Cell projection, dendrite. Note=Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner.
Protein: PRXD1_MOUSE
Sequence: MAGSELRAELEQRLGALAIRTEVVEHPEVFTIEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNDLGKQLGVGSGNLRFADETAMLEKLKVGQGCATPLSLFCDDGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLIFVKATGHDPIILNFD
What are the official names of this protein?
Prolyl-tRNA synthetase associated domain-containing protein 1, PrdX deacylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRORSD1 family.
Protein: CYB_NECTE
Sequence: MKIMRKNHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGICLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYTLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTFKDLLGILLLLMALMILALFFPDILGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILATFPLLNTSKQHGLIYRPITQTIYWIFIANLLVLTWIGGQPVEYPFTMIGQIASITYFGIIIILMPISNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ERA_CLOBL
Sequence: MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKIYSELMEFEEIIPISALKGKNIDLLKELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPIIIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.