PharMolix/UniProtQA huggingface dataset:
Protein: PLSB_ECO8A
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AVR3_CHICK
Sequence: MVHTTSPLLLLLLLSLALVAPSLSARKCSLTGKWTNNLGSIMTIRAVNSRGEFAGTYLTAVADNPGNIKLSPLLGIQHKRACQPTFGFTVHWNFSESTSVFVGQCFIDRSGKEVLKTKWLQRLAVDDISDDWKATRVGYNNFTRQRTVEE
What are the official names of this protein?
Avidin-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the avidin/streptavidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOC_SHIF8
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGDEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_YERP3
Sequence: MNEKHPGPLVVSGKLSDGERMKSESNFLRGTIAEDLNNGLTGGFSGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMMLRCRLPGGIITPQQWLGIDKFAADNTLYGSIRITNRQTFQFHGILKGNVKPAHQLLNELGLDALATANDVNRNVLCTSNPVESALHQEAYEWAKKISEHLLPRTRAYAEIWLDAEKVATTDEEPILGATYLPRKFKTTVVIPPQNDVDLHANDLNFVAVADKGKLIGFNVLVGGGLSIAHGDKNTYPRKASEFGYIPLKHTLAIAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVEKRAGVSFSAIKPYQFTGRGDRIGWVKGVDKKWHLTLFIENGRLLDYPGRSLKTGVAEIAKIHQGDFRLTANQNLIVAGVPEKDKARIEALAREHGLMDDNVTSQRENSMACVSFPTCPLAMAEAERFLPEFVTRVEGILQQHGLADEHIVLRVTGCPNGCGRALLAEVGLVGKAVGRYNLHLGGNREGTRIPRMYRENITADEILLITDQLVGRWAKERHVDEGFGDFVIRAGVIAPVIDSARDFYDVQEAM
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RSMH_WOLPM
Sequence: MTHTPVLLKEMLSLLSPQDGGIYVDATFGAGGYSKAILESADCKVYAIDRDETVTKFYDDLSVRYPDRIKLFIEKFSNIKSILSSVEPSPVIPVLDTGKNNWSRAGMTSNGVDGVVFDIGVSSMQLDNGDRGFSFLHDGPLDMSMDNSSYINASTFVNALREEEIANTIYNYGGERHSRKIARAIINARKKKTIKTTFELADIVRSVVFRGKSKIDPATRTFQAIRIWVNDELEELEKGIKAASEILSENGKLIVVTFHSLEDRIVKTFFKDLCATDCKTFSLLNKKVIEASIEEVSANPRSRSAKLRAIQRLS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DINI2_ECO57
Sequence: MPHRYPAAKINKMPKGSVPALQQEMLRRVSKRYDDVEVIIKSTSNDGLSVTRTADKDSAKTFVQETLKDTWESADEWFVR
What are the official names of this protein?
DinI-like protein Z2083/ECs2153.
Protein: YCGR1_DECAR
Sequence: MSSTQEDQPNPDFEIDHPEAYSQYFLTAPREISFYLNLLVKRGSLLTAHIDDGKAFFLTTMIAVDDEKQAIFLDSAQADELNTAAKNAHRITLTAKLDRVKIQLRLPPLRHQLVDGQKMLVAAFPQAILRIQRREFFRLESSSAHPILCRIAMEAPEGTLKTFEWNVADISGGGLSLNAPTSLINDCQRDALFKNSRLDIPGEGVLLVNLRVRKTSEFSAENGQHYLRVGCEFVELPGSRLAMIERYIARIERERKARDSGLAN
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR 1, Cyclic di-GMP binding protein YcgR 1.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: MRAZ_ECOLI
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: EFTU_GEOSW
Sequence: MAKEKFERKKPHVNIGTIGHVDHGKTTLTAAITAVLAKQGKAQARAYDQIDAAPEERERGITISTSHVEYETDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYDFPGDEVPVIKGSALKALEGDPQWEEKIIELMNAVDEYIPTPQREIDKPFMMPIEDVFSITGRGTVATGRVERGTLKVGDAVEIVGLADEPKSTTVTGVEMFRKLLDQAEAGDNIGALLRGVSRDEVERGQVLAKPGSITPHTKFKAQVYVLTKEEGGRHTPFFSNYRPQFYFRTTDVTGIITLPEGVEMVMPGDNVEMTVELIAPIAIEEGTKFSIREGGRTVGAGSVSEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAST4_MOUSE
Sequence: MGEKVSEAPEPVPRGCSGHGARTLVSSAAAVSSEGASSAESSSGSETLSEEGEPSRFSCRSQPPRPPGGALGTRLPAAWAPARVALERGVPTLPLPHPGGAVLPVPQVSSASQEEQDEELDHILSPPPMPFRKCSNPDVACGLGKSLKYKRQLSEDGKQLRRGSLGGALTGRYLLPNPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLCRTSNRKSLIGNGQSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFFELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSRTAETPEMDESVSSSNTSLRLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQELITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFTVEIRQFSSCSHRFSKVFSSIDRITQNSGEDKDDSEDKTKSTTLPSTETLSWSSEYSEMQQLSTSNSSDTESNRCKLSSGLLPKLAISTDGEQDEAVPCSGDPREEPEKPVPPSEECTQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSEPTSHVARQRLESTEKKKISGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPAYQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKGRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNAKITQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKLLCSRKHSLEVTQEEVQREQCQREVTLQSLEENVCDAPSLSRARPVEQGCLKRPVSRKVGRQESVDDLDRDKLKAKVVVKKPEEKHESHQKPHSLGGDSESYALFRLEEREKKVYSKGLERSGHFENTSAELPSVGSLLKDTLHKQASVRASEGVTSDGAACSLTPGEHSQSLGDFKRASASGILHDSVCPISDRPAPGKVEYSEKASQAKELLRSEKLDSKLANIDYLRKKMSLDDKDDSHCAILKPKITSSAHECLPGNPIRPMAGQQETPPASENRAFINSTHTPQMSAVSFVPLKALAGRVENGGEKAGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPHASKTELLSPEPAQSPSPGINVGPCVPLALPGSSGKKGDSTSLREPSSANLKVNKSYLLEPRFLPPSRALQDSLAASGPEPKSKPERKLIHPSARSPATVTESNLQQKEGGPATHQDRSTDTRNLPGPGQTLHNVDLPRLCTRAPLPPEGTPAKEKPCLKEPSAKVKSEWSAVRDDGHRDPCAKLCPAETGKASDSSKPLPSGGRTQPDFYKQTQTSEKAWAHAKTNHKDSQDEVKSLAREDSASLLYEKEIGRARKGPEPKPEVPATRCPPQPPGIEGEKREKLSAAPSLQKQAPKEPDRKEQTSQRPGGSGPQQPPPTKELSNSASWQHGSSPSHTLKKEPGTKAAAAEPSTSLHDTPRSATATTTAIATTTTTTSAGHSDCSSHKARPGPDPSPSKSKHQDRSLSSQKLSAGSAKGKEPVTQPLGGSIREGKGGSKGPVDTFSAVLTTQGKASDVLVQGEGRVSIIVHTEECPLDAKLKNTNGGCPPEMQAKHPPRQGHLSEAADQKPLIAGEKQSPSPKHPKPSTVKDYPSLCRQTDRSPSHQATTGDRKAEGKKCTDALYVAAPEGYKPEASPSLHHGETGLRGSERPPMGMGKGFSEPKGKGPGPQKSLAETGKPSGMKRSPSATVQSSLRSAAPPEKSLSYSASFPEAQPGVREVPAANSSPSSAKATGGTSEFPAPSSRDHRKLQSGGDGRSQMIKSDSLPSFRLSTSALESHFQDPQVPIASGHRGRALSVTAATGEPKGRELAQPPPVRKQNACREATRAPPAPSTDRSLPLSSEKDFVVRQRRGKETLRSSPHKKAS
What are the official names of this protein?
Microtubule-associated serine/threonine-protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_PSEPK
Sequence: MIALIAAVSAGGIAGTLLRFATTNWVAAHWPRHFYAGTLAVNLVGCLLIGLLYGLFLHKPLAPVELRAGLIVGFLGGLTTFSSFSLDTVRLMESGQVPLALGYTSISVVGGLLATWAGLSLTRF
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STEEP_DROME
Sequence: MPKVVSRSIVCSDTKDQEEYNEEKPLNIYYCLCNKMALILDCTLEQLPLREVDNARVINANDHANKLTHNPTPRMVYIKRKSRGNGIEKQYRYKCRSCSLPLYYRHSPDSHVTFVMSNALIRNKGESPLTQLLNSEIKGSFKAPAAKPATSAGPDDSGIVDASGKKVVVTRHTKNMGKFSSVTVSTIDEEEDEIEAREIADSYANNARIIEKQLQRKGGKLSDVGIKTKTEDAPPPQKKQRGTLLER
What is the function of this protein?
Stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport (By similarity).  Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers (By similarity).
What are the official names of this protein?
STING ER exit protein, STEEP.
What is the protein family that this protein belongs to?
Belongs to the STEEP1 family.
Protein: PAN_THEGJ
Sequence: MGSFDEVSHDTGYEDYITFLKRRIRQLELQVRTLEADKERLERELSRLRTEMSRLRQPPAFAGTVIEVLDDDRAIVQNYNGPRFVVRIAPWIERDKLKPGSRVALDQRTMAIVELLPTEKDPSVLGFEVIEKPRVTYQDIGGLERQLAELREAVELPLKHPELFEKVGIEPPKGVLLYGPPGCGKTLMAKAVANHVNATFIRVVGSELVRKFIGEGARLVHELFEMAKEKAPTIIFIDEIDAIGAKRMDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFRGRLEILKVHTRKMNLRNVDLSIIADITEGASGADLKAIATEAGMFAIRDRRTYVTQEDFLKAVDKVLGAEKRLAQAIAMHEVMYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HA22G_ARATH
Sequence: MIGSFLTRGLLMVFGYAYPAYECFKTVELNKPEIQQLQFWCQYWIIVAALTIFERIGDALVSWLPMYSEAKLAFFIYLWFPKTKGTTYVYDSFFRPYIAKHENEIDRNLVKVKTRAKDMAMIYLQKAINQGQTKFFEILQYITEQSTPKSKAEEKKETTIPKLDDPILKVKENEVTK
What are the official names of this protein?
Putative HVA22-like protein g, AtHVA22g.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
Protein: LYG_CHICK
Sequence: MLGKNDPMCLVLVLLGLTALLGICQGGTGCYGSVSRIDTTGASCRTAKPEGLSYCGVRASRTIAERDLGSMNKYKVLIKRVGEALCIEPAVIAGIISRESHAGKILKNGWGDRGNGFGLMQVDKRYHKIEGTWNGEAHIRQGTRILIDMVKKIQRKFPRWTRDQQLKGGISAYNAGVGNVRSYERMDIGTLHDDYSNDVVARAQYFKQHGY
What are the official names of this protein?
Lysozyme g, 1,4-beta-N-acetylmuramidase, Goose-type lysozyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 23 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCA_VIBCH
Sequence: MSLNFLDFEKPIVELETKIQALRDVSRHSTSASVDLDKELEQLEKKSLELKKKIFSDLGAWQVAQLARHPQRPYTLDYLKHIFTEFDELAGDRAYADDKAIVGGIARLEGRSVMVIGHQKGRETREKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEAIAKNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSDKAPQAAEAMGLIAPRLKELELIDEIIEEPLGGAHRDHKQTAENVKATLLRQLADLDALDHENLLERRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMS1_YEAST
Sequence: MNSQKASKMTGSLKKNDLYIFDLSEQLLNSLKLMSFDSTLREVEVEKTSDNDRNKESGDLQIARKKVTSNVMRCSVCQMSFDSRNEQKAHYQTDYHLMNVKRNLRGLDILSVEEFDALISKEHGIKSEDENSGGEQTSSDHEESEEASDRDPDLQTNNYMETIIENDLQKLGFQKDESDAISHINTQSPYIYFKSKYLQKNEVLAIYKSLFNKRSLSNPNEALTFWNSQENPMAISALFMVGGGHFAGAIVSHQRLNVKGNAHKKDETLIEQAVNFLEHKTFHRYTTRRKQGGSQSAMDNAKGKANSAGSALRRYNESALKTDIQGVLKDWEPYLSKCDNIFIRARNVSDKKIFTDNTVLNKGDERIKSFPFTTNRPTVLELKKAWCELSYLKILPKPEPLAVKETVQKLEVSNKKDEFKEKQEPLLEEIQTEEIISLLKKGRAPLLISFLKKNKLDGNFRLKPESKYSLTPTMLHYASQQGMKQMALILLSNIKCDPTIKNRLGRTAWDLNRNDDVRHAFQIARYNLGESFTNWDETHIGQPLSREQVDEINEKKKAIENEKAEKLIKLELEAAKEKQRFAKDAERGPGKKLTNIPSIQQQNLNSLTDEQRRRLMREQRARAAEERMKKKY
What is the function of this protein?
Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway.  Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD), which is necessary to maintain mitochondrial, cellular, and organismal viability.
What are the official names of this protein?
Protein VMS1, VCP/CDC48-associated mitochondrial stress-responsive protein 1.
What is the protein family that this protein belongs to?
Belongs to the ANKZF1/VMS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=translocates from the cytosol to mitochondria upon mitochondrial stress.
Protein: PDIA6_CAEEL
Sequence: MALIKLLLASLAITSVCGMYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVGAVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARLGGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCKSLEPQWKAAASELKGKVRLGALDATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGGRQSSDIVAWASARAQENMPAPEVFEGINQQVVEDACKEKQLCIFAFLPHILDCQSECRNNYLAMLKEQSEKFKKNLWGWIWVEGAAQPALEESFEVGGFGYPAMTALNFRKNKYAVLKGSFGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEKWDGKDGALPAEDDIDLSDIDLDKTEL
What is the function of this protein?
May function as a chaperone that inhibits aggregation of misfolded proteins (By similarity).  May negatively regulate the unfolded protein response (UPR) through binding to UPR sensors (PubMed:24508390).
What are the official names of this protein?
Protein disulfide-isomerase A6 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NADK1_THEVB
Sequence: MQLNQVIVVHKAGDRQSKEWADRASRQLQQRGANVLVGPSGPKDNPYPVFMASVTEPIDLAVVLGGDGTSLAAARHLAAAGVPILAVNVGGHLGFLTEPLELFRDMEAVWDRLERDEYAMQQRMMLQAQVFEGSKAHPEAVGDRYYALNEMCIKPASADRMITAILEMEIDGDVVDQYQGDGLLVATPTGSTCYTVAANGPILHPGMEALVVTPICPLSLSSRPIVLPARSSVSIWPLEDHSLNTKLWMDGVLATSIWPGQRVQVTMADCQARFIILRDHYSFYQTLREKLAWAGARIPYHNNHRN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZHD6_ARATH
Sequence: MEVREKKDEKMEMTRRKSSALDHHRLPPYTYSQTANKEKPTTKRNGSDPDPDPDLDTNPISISHAPRSYARPQTTSPGKARYRECQKNHAASSGGHVVDGCGEFMSSGEEGTVESLLCAACDCHRSFHRKEIDGLFVVNFNSFGHSQRPLGSRHVSPIMMSFGGGGGCAAESSTEDLNKFHQSFSGYGVDQFHHYQPKKRFRTKFNEEQKEKMMEFAEKIGWRMTKLEDDEVNRFCREIKVKRQVFKVWMHNNKQAAKKKDL
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Zinc-finger homeodomain protein 6, AtZHD6, Homeobox protein 24, AtHB-24.
What are the subcellular locations of this protein?
Nucleus. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Protein: HEMH_SALNS
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGLPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFAMHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIOX1_ARATH
Sequence: MATNFKSLLPVIDISPLVVKCDDANMAEDAGVAEVVGKLDRACRDAGFFYVIGHGISEDFIRKVRVMSHQFFELPYEEKLKIKITPAAGYRGYQRIGLNLTNGKQDMHEAIDCYKEFKQGKHGDIGKVMEGANQWPENPQEYKELMEEYIKLCIDLSRNILRGISLALGGSPYEFEGKMLTDPFWIMRILGYPGVNQENVIGCGAHTDYGLLSLINQDDDKTALQVRDLAGDWIPVIPIPGSFVCNIGDMLKILSNGVYESTLHRVINNSPRYRVCVGFFYETNFDAAVEPLDIFKEKYPGKGTSQVFKRVVYGEHLVHKLQTTFQNLVEHS
What are the official names of this protein?
Probable 2-oxoglutarate-dependent dioxygenase At3g49630.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PUR7_STRS7
Sequence: MSNQLIYSGKAKDIYETADDEIVLISYKDQVTMLNGAHKEMIEGKGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSKRFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAYLKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLGSLTQAYETVLERLRALDQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: GLV5_ARATH
Sequence: MTNITSSFLCLLILLLFCLSFGYSLHGDKDEVLSVDVGSNAKVMKHLDGDDAMKKAQVRGRSGQEFSKETTKMMMKKTTKKETNVEEEDDLVAYTADYWKPRHHPPKNN
What is the function of this protein?
Signaling peptide (root growth factor) that maintains the postembryonic root stem cell niche in a PIN2-traffic dependent manner (PubMed:20798316, PubMed:23370719).  Root growth factor that regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells (By similarity).  Influences the longitudinal growth rate in the primary root in response to phosphate ion (Pi)-deprivation (PubMed:25856240).
What are the official names of this protein?
Protein GOLVEN 5, CLAVATA3/ESR (CLE)-related protein CLEL1, CLE-Like protein 1, Root meristem growth factor 2, AtRGF2.
What is the protein family that this protein belongs to?
Belongs to the RGF family.
What are the subcellular locations of this protein?
[GLV5p]: Secreted.
Protein: MNME_FRAT1
Sequence: MYTKDTIVAIATPQGNGGIGIIRISGIDALAIAEKLTKKQLKPRYATFCNVYNDNEIIDHGIIIFFKAPLSYTGEDVVEIQAHGNPFILNLIIKAALNCGARMAKAGEFTERAFLNNKLDLAQAEAVADIINASSEIAAKSAAKSLQGDFSKEINNLLEKLIYLRMYVEASIDFPEEEINFLEDQKIHSSLEEIYKVILAVKNSCKQGVILAEGITLILVGKPNAGKSSLLNALAGKESAIVTSIAGTTRDIVKEHIQINGVPMHIIDTAGLRNSDDIIESEGIKRAIKKIQEADQVLFVTDDYTNSQVKFSDIKEIIPEFYDQIPKDIDITYVHNKIDLLKEVPHNHANHIYISAENNIGIDKLKEHILNKVGYTNQNESIYTARERHVTAINNAFEHIKLAKEQLELGNGELLAEELLIVQEYLNSITGEFSSDDLLGEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP85_HHV6Z
Sequence: MITHAMEGSKTFNIPTFVLDENCNFIPDVLSRANAKFIKEVLIRDSYNAVCLANSFIPMATQTVEQILIIITKFKFSRSRDLLMSVFRLGVHINRFYAGKNQVKHMITMMKSLFDTEEAMRQLDRALMGLFVDARDNSYMPLIALSLHENGLPDSKFIKAVRLIQTTVNSFHNRPDADIEQYAEKLRAYNYLYKIPKYSLKEAVDIYSDNLKDLTIGVNKKPTLLFTSSDDAYLSHIYNDLLFLTSTWNMIYNCKKEIRRLNTWIKYEINSIMETAVLVGFQLPDLKETILDLAALISNMNLVSPDKELFPHYKLILAKLFEICIFATKANICILPSFIKGHLIEFEDVLKRSNDDEDLNYLLLKSRDSDDEYDEDKPPIQVDPGRVDNVLTDSDFFNVTPENAFSSIAIMPISYDKTIDVEDNEIQVLEVEMQSLSAVVYGAVASKYGLSLEQVIRKLNRNEGRTSSRASPSHSTSTVPYSPPQSDRSTPTSILRQRVPMRSNSRSSSVSFSQEDSNRSHYSDETNISDYSYPMADLELEDEEPMEDHPHSPQSTSSNNSMSRQSRALQNGQRRRAPTMVPSSQTRRQNNARPRRVARRLTEMMNDARL
What are the official names of this protein?
Phosphoprotein 85, pp85, Protein U14.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae pp85 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Note=Expressed exclusively at the cytoplasmic level during the late phase of the virus replication cycle. Also found in dense bodies (By similarity).
Protein: FABV_PSYIN
Sequence: MIIKPKIRGFICTTTHPVGCEKNIQAQIEYTKQQGKIANGPKRVLVIGSSAGYGMSSRVAAAYGSDASTIGVFFEKPATEKKPGSAGWYNSAAFEKQAKADGLYAKSINGDAFSHEIKAKVVELIKQDLGQIDAIIYSVAAPVRKLPDTGEVIRSSLKPIGETYISTAIDTNKDVIINATVEPATEEEVADTVTVMGGQDWELWLSALGEAGVLAEGLKTVAYSYIGTELTWPIYWDGALGKAKIDLDRASTAIQAQLAPLNGEAYVSVQKSVVTQASSAIPVMPLYISMVFKIMKEKGLHEGCMEQIYRLFTSQLYKQDGSAPETDQARRIRLDDWELRDDVQQACKELWPKITTENLFELTDYKEYKEEFVQLFGFSIDGVDYDADVDTVVEFDCLSV
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.