PharMolix/UniProtQA huggingface dataset:
Protein: RL22_HAES1
Sequence: METIAKHRYARTSAQKARLVADLVRGKKVAQALEILTFTNKKAAALVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ATC2_SCHPO
Sequence: MPTYNDDDDSSRPPSVHSERNQKPSSSQFLGVPSSNYNQRENSSRSGSSTISREPSSSGTMYPMASRDSMKESYDKNKGTPPDYTSYVSHSDAEPEQASSKSSTSIEDLLHTEYDDAPFAFSIPLLQRLQDPKNTSLLHAIHGLKGLCKGLKVDPSTGISTHEPHYADKLQMSDILNDDSNPKLVVHLDRIRSQDNNPEAKVSHDSDRVKYYGKNVLPEHDSKGLIRLMLEAFKDKVLILLSIAAVVSLALGLYQTFGQPPTLDPITGKPEPRVEWVEGVAIMAAIVIVVTVGGVNDWQKELQFKKLNAKVSNFDVQVLRDGAVHSTSVFDLVVGDVLFVEAGDVVPVDGVLIESNNLVLDESAMTGETDNIKKVDANTAIERTSPDVEYRKNADPYLISGTTILEGNGKLLVTAVGVNSFNGRTTMAMRTEGQATPLQLRLSRVADAIAKLGGAASALLFIVLLIEFLVRLKSNDSSSKNKGQEFLQILIVSVTLLVVAVPEGLPLAVTLALAFATNRMQKDNNLVRHLQACETMGTATNICSDKTGTLTQNRMTVVAGGFGTDVLFFDHNDETPTNVDQGSDSSKFEDAGASAFAFKRLSPELRDLTLYSIAVNSTCRQLFEDNSDTPRFIGSKTETALLDMSVKELGLTNVDSMRSSVDIKQFFSFSSDRKASGAIFEYKDKYYFVVKGMPERVLQQSTSVITNGSLDEVEDMHSHADYFKEMITGYAKRSLRTLGLCYRVFDSWPPKDIPTNDEDSSNPLKWEDAFTDMTFLGFFGIMDPIRPDVPLAVKVCQGAGVTVRMVTGDNIVTAKAIASQCGIYTEDGISMEGPEFRSLSDEKRLEILPKLDVLARSSPLDKQLLIEGLQKLGNVVAVTGDGTNDAPALKKANVGFSMGKSGTEVAKEASDIILMDDNFSSIVKAIAWGRTVNDAVKKFLQFQITVNITAVFLTIISAVASTDQSSVLTAVQLLWVNLIMDTLAALALATDPPTPEVLKRKPEKPGASLFTFDMWKMIICQSMYQLAVTLVLHFAGNSIFHYPSNTADMNTIVFNTFVWLQLFNEINNRRLDNKLNIFERINHNFLFIAIFVIVAGIQVIIVFFGGAAFSVKRIDGKGWAISIVFGVISIPLGALIRCVPNNFLRKVLPVKTIDTVFSWILNPRFRSKRRSTDHDVESLSLIPYEPTSPNEVIDSIRHSLGFVQRIRGGRIRHLLNNSKFDKQMEALPERLRPRVKQRFMKIRSPSVSSATSVALMIPISTLVSEASGRLGGHDIWISHNRQALDKKSSNVH
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.  Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.
What are the official names of this protein?
Calcium-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: FENR_STRMU
Sequence: MEEEKLTSEKEIYDITVIGGGPVGLFTAFYAGLRGISVKVIESLSELGGQPAILYPEKVIYDIPAFPAITGADLVDNLIEQLERFKDKTTICLKEEVKTFEKENAIFTITTNKGNHFSKAIIIACGNGAFAPRRLGLDDEERYADHNLFYNVHKLDQFAGKKVVICGGGDSAVDWANALDKIAESVTLVHRRDAFRAHEHSVEVLKTSHVNIMTPYVPLELKGEGDEATSLVIQKVKSEETKELSLDSLIVSFGFSTSNKNLKSWNIDYKRSSINVSPLFETSQTGVFAIGDAAEYEGKIDLIATGFGEAPTAVNQAIKYIYPERDNRVVHSTSLIK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: URE3_DELAS
Sequence: MELTPREKDKLLLFTAALVAERRKARGLKLNYPEAVALISAAVLEWARDGRTVAELMHLGTTVLTRADVMEGIPEMIPDIQVEATFPDGTKLVTVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_HAEIN
Sequence: MSQTHRILLLNGPNLNMLGAREPKHYGSISLESIEEKIQTLATQHNVKVECFQANSEGKLINKIHESFQQVDFILINPAAYTHTSVALRDALLAVSIPFVEIHLSNVHKREPFRHHSYFSDVAEGVICGLGAKGYEFAFLFAMDYLAKK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SCN1B_HUMAN
Sequence: MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE
What is the function of this protein?
Cell adhesion molecule that plays a critical role in neuronal migration and pathfinding during brain development.  Stimulates neurite outgrowth (PubMed:21994374).  Has no regulatory function on the SCN2A sodium channel complex (PubMed:14622265).
What are the official names of this protein?
Sodium channel subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN1B (TC 8.A.17) family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection. Cell projection, axon. Note=Detected at nodes of Ranvier on the sciatic nerve. SUBCELLULAR LOCATION: [Isoform 2]: Perikaryon. Cell projection. Secreted. Note=Detected on Purkinje cells and their cell projections and on neuronal cell projections.
Protein: LEU1_BACP2
Sequence: MRKINFFDTTLRDGEQSPGVNLNAQEKLIIAKQLERLGVNIIEAGFPASSRGDFLGVQEIARTIKNCSVAGLARCVKGDIDAAWEALKDGVEPRLHVFIATSDIHLKHKLKKTREEVVEQAVAMVKYAKERFPVVQWSAEDACRTDLDFLAEIVEKVIDAGASVINLPDTVGYLAPKEYGNIFKYMKEHVPNIDRVNLSAHCHDDLGMAVANSLAAIENGADQIETAVNGIGERAGNAALEEIAVALHIRKDFYQVESTIQLNEIKRTSDVVSKYSGMIVPRNKAVVGNNAFAHESGIHQDGFLKEKTTYEIISPELVGVTTDVLVLGKHSGRHAFKDRMKTLGFKLTEEEINKFFETFKNLTEKKKEITDDDLISIILEEKVADRKIGYEFESLQVHYGTEQMPTATVSLKNQETQEVIQEAATGAGSVEAVYNTLERCMEERIHLLDYRIQSNGKGRDALAEVYVTVSIEGKETAGRGVAQDVLEASAKAYVNAVNRHLIFKSNLIEIEKHHAIS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: NUSB_BART1
Sequence: MADIKSRHFPRSANKRGAARLAAVQALYQMDIVGSGVMETAAEYEAYRLGKDIDGDQYLDADFQWFLAIITGVVQDQKQLDPLLHQQLSAEWSLSRLDSILRAILRAALWELINRKDVPVAVVVNEYVDIAKAFFEGDEPKLVNAVLDSMAKKIRL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NIKE_STAAB
Sequence: MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTLASLVLGLFKPVKGEIYLSDNAVLPIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTAQDQLLIQHLSTFELNAQLLTKLPSEVSGGELQRFNVMRSLLAQPRVLICDEITSNLDVIAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFTIEELFNVDRHSYTKELVQAFSY
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import system ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPD_THEMA
Sequence: MNVAILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVVEKRVFHEKVLGIVEGGDTRSQSVRSALEFLEKFSPSYVLVHDSARPFLRKKHVSEVLRRARETGAATLALKNSDALVRVENDRIEYIPRKGVYRILTPQAFSYEILKKAHENGGEWADDTEPVQKLGVKIALVEGDPLCFKVTFKEDLELARIIAREWERIP
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: REP_TYDVA
Sequence: MPSAPQKTKSFRLQTKYVFLTYPRCSSSAENLRDFLWDKLSRFAIFFIAIATELHQDGTPHLHCLIQLDKRSNIRDPSFFDLEGNHPNIQPAKNSEQVLEYISKDGNVITKGEFKKHRVSPSKSDERWRTIIQTATSKEEYLDMIKDEFPHEWATKLQWLEYSANKLFPPQPEIYQATFTEEDLQCHEDLQLWRDQHLYHEPRRAGTRIPSLYICGPSRTGKTTWARSLGRHNYWNGTIDFTVYDDHATYNVIDDIPFKFVPLWKQLIGCQSDFTVNPKYGKKKKIKGGVPCIILCNDDEDWLKNMSPAQIEYFEANCITHFMYAAETFFAPESSSH
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities.  Acts as an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FAR1_BRUMA
Sequence: MYHRLILLALVGTTMANVIPFSMSNIPEEYKEFIPEEVRNFYKDLTVEDKEILRELASKHATFANEDAALEALKDKSDKLYKNAVELRNFVKAKIDSLKPDAKIFVDEIIAKARSLRSDDGHKLDTEKIKQAARDIIAKYQALSEETKEELKVTFPAIAKIIGNEKLKRNASTFLQKN
What is the function of this protein?
Binds retinol.  Also binds the fluorescent fatty acid 11-((5-dimethylaminonaphthalene-1-sulfonyl)amino)undecanoic acid (DAUDA).  The long chain fatty acid oleic acid can act competitively to displace bound DAUDA and retinol.
What are the official names of this protein?
Fatty-acid and retinol-binding protein 1, Bm-FAR-1, Bm20.
What is the protein family that this protein belongs to?
Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FETP_SHEHH
Sequence: MARTVNCVYLNKEAEGLGFQLYPGDLGKRIFDNVSKEAWALWQSKQTMLINEKKLNMMNVDDRKFLEEQMVNFLFEGKDVEIEGYVPQKDDE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: DNAA_TRIEI
Sequence: MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYIKTIADVVHDILGYPVEIYLTTFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLNAKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGGVGLGKTHLMQAIGHYRLDIFPHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHTFNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYENMVLPRDVIEYIATRYPSNIRELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEASPEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMRQHTDLSLPKIGEVFGGKDHTTVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHF10_HUMAN
Sequence: MAAAAGPGAALSPRPCDSDPATPGAQSPKDDNEDNSNDGTQPSKRRRMGSGDSSRSCETSSQDLGFSYYPAENLIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSQMQQQNTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQVPQGKYKVLPTERTKVSSYPVALIPGQFQEYYKRYSPDELRYLPLNTALYEPPLDPELPALDSDGDSDDGEDGRGDEKRKNKGTSDSSSGNVSEGESPPDSQEDSFQGRQKSKDKAATPRKDGPKRSVLSKSVPGYKPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCVGLGAIPSGRWICDCCQRAPPTPRKVGRRGKNSKEG
What is the function of this protein?
Involved in transcription activity regulation by chromatin remodeling.  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors.  During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
What are the official names of this protein?
PHD finger protein 10, BRG1-associated factor 45a, BAF45a, XAP135.
What is the protein family that this protein belongs to?
Belongs to the SAYP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_LACP3
Sequence: MATRLDGRAVSKKILADLKQTIAQLAQHDVTPTLAVVLVGSNPASEVYVRNKQRRAEDIGVRSLMFRMPEATTQADLLAKVAELNHDPDIDAILVQLPLPAGLDEQAVIDAIDPDKDVDGFSPVSVGRLWANEPTVVASTPYGIMALLDAYDIDVAGKRVVIIGRSNIVGRPLAGLMVNHDATVTIAHSKTRDLKQLAKEADILVVAVGVPHFIGADAVKPGAVVIDVGISRGADGKVLGDVDEAAVAPIASAITPVPGGVGPMTIASLMAQTVTLAKRRANG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YETB_SCHPO
Sequence: MVNAQQLELLIQNTLEPTHIEIQDMSGGCGQNFEVIIVSPLFEGKSTLARHRLVNHKLQEVIKDIHAFTQKCYSPAQWEALQAK
What are the official names of this protein?
Uncharacterized bolA-like protein C8C9.11.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: HIS6_BURP6
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDAQGADELTFLDITATSDGRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPPLVRDAADKYGSQCIVVAIDAKRVSADGEPPRWEVFTHGGRKGTGLDAVEWARKMAELGAGEILLTSMDRDGTKAGFDLALTRAVSDAVPVPVIASGGVGSLEHLAAGITEGHADAVLAASIFHYGEHTVGEAKRFMAERGIAVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_VIBC3
Sequence: MIVRTLEECRQSERRVVAENWESVRMLLKDDHMGFSFHITTIYANTQTHIHYRNHLESVYCMSGEGEIEVVGGKTYPIQPGTLYILDQHDEHYLRAFSSEMVMACVFNPPLTGHEIHDAEGVYPLDKSELISQCHKEK
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: MT2A_SOLLC
Sequence: MSCCGGSCGCGSGCKCGSGCGGCGMYPDMEKSTTFTIIEGVAPINNYGNVEEKAAGEGCKCGSNCTCDPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein type 2 A, LeMT(A).
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: RPOZ_MYCBP
Sequence: MSISQSDASLAAVPAVDQFDPSSGASGGYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHADLLEHTEGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: OLSA_BRUA2
Sequence: MIGTIRIFLVVAAMVALSLSLIPFQYLFLKLKNGWKRRLPNFFHRIVARLFGFRIRTVGKLHEGCPLLLVSNHTSWSDIVVLSAVGQVSFIAKSEVRDWPVFGMFAVLQRTVFVERARRGKTVHQTSEIANRLIAGDAMVLFAEGTTSDGNRVLPFKTALFGAAHAAIREAGVAEVAVQPVAIAYTRVHGMAMGRYFRPLVSWPGDVELMPHLKGILREGAIDVEVRFGEPVFVTAETDRKALARTMENRVRALLQSALLGREIPEA
What is the function of this protein?
Catalyzes the second step in the formation of ornithine lipids, which are phosphorus-free membrane lipids.  Uses acyl-acyl carrier protein (acyl-AcpP) as an acyl donor and converts lyso-ornithine lipid (LOL) into ornithine lipid (OL).
What are the official names of this protein?
Lyso-ornithine lipid O-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. OlsA subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VM3B_BOTJA
Sequence: IISPPVCGNELLEEGEECDCGTPEN
What is the function of this protein?
Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like botrocetin, Snake venom metalloproteinase, SVMP, von Willebrand factor-dependent platelet coagglutinin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAC_SHEAM
Sequence: MLQVTPSQISGIIESGGVVAYPTEAVYGLGCDPDNDTAIQKLLAVKQRPWEKGLILIASSFDQLKPYIDLSRVTEAQLQAAFDKWPGPFTFVIPAKADVSPMLRGCFDTIAVRVSAHQDVRAMCYACQKPLVSTSANLAGEQPALTLAEVQTQLGDKIDAVVLGALGQSCQPSTIIDIQTGHIFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHE_RHOCB
Sequence: MRILFVHPNYHSGGAEIAGNWPPSWVPYLAGHLKKAGFDDIHFIDAMTLNVSHDELRKKFAELQPDLIGVTSITPSIYEAEETLKIAKEVVPNAVRVLGGVHATFMFRQVLSEAPWVDAIVRGEGEEIMVELAKCVSEGRWPEDRASIKGLAFHDGTEIVATQAAPTVKDIDSLKPDWSLIDWKHYIYIPLGVRVAIPNMARGCPFTCSFCSQWKFWRDYRVRSPKAVVDEIEDLVNNYDVGFFILADEEPTINKKKFVEFCQEMIDRGLNHKVKWGINTRVTDIYRDRDLLKFYREAGLVHISLGTEAAAQLKLDLFNKETTVAENKEAIRLLREADIFTEAQFIVGLDNETKETLEETFQMAWDWQPDLANWSMYTPWPFTPLFQELRDQVEVFDFSKYNFVTPIMKPKALTRGELLDGVMKNYRRFYMRKALFHYPWRGTGFRRRYLLGCLKAFLKAGVGRTFYDLGKAGYWGPQTKDTVDFHFDETRKIAEAQVADWEAAADRSRKHKERQEALRAQMKDRAADRNTANFVMPADAEDEFDLSAETHEARSAEHAAMACGGGKDQMVDAAE
What is the function of this protein?
Involved in the tetrapyrrole biosynthetic pathways leading to chlorophyll and bacteriochlorophyll (BChl).  Catalyzes the anaerobic formation of the isocyclic ring (E-ring) in Mg-protoporphyrin monomethyl ester (MPE) to yield protochlorophyllide a (PChlide a) via a six-electron oxidation and the formation of an oxo group at position C13 using oxygen from a water molecule.
What are the official names of this protein?
Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase, MPE cyclase.
What is the protein family that this protein belongs to?
Belongs to the BchE family.
Protein: Y1492_BRADU
Sequence: MAPTGKRTGESTRSTGPAPPSSAGYLDGRLLIAMPVMGDARFERSVIYLCAHSAEGAMGIIVNHPAGSIDFPELLEQLGIIRKGEHIKLPENAESMKVLRGGPVDTGRGFVLHSSDFYIENATLRIDDGVCLTATVDILRAIANGSGPKHAILALGYAGWAPGQLETEIQSNGWLHCDADADLIFGDDVDEKYGRALRKIGIDPGMLSNEAGHA
What are the official names of this protein?
UPF0301 protein blr1492.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RUVC_PROMT
Sequence: MRIIGIDPGLARVGYGIIDEIEGKKIMIDCGIIETKSTQKEEERLVEISNDLSSIIKKWNPNSAAVEKFFFYRSSTTISVVQARGVIMMTLGKYKLPIQEFPPMQIKLAVTGYGHSDKNDVLNSVMHELNVTSPPKPDDAADALAIALTGIYLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SH_MUMP6
Sequence: MPLIQPPLYLTFLLLMLLYRIITLYVWSLSTITYKTSVRHASLYQRSFFRWSVDHSL
What is the function of this protein?
Plays a role in the inhibition of the host NF-kappa-B pathway.  This inhibition occurs at the receptor level, by preventing the signaling of TNFR1 as well as IL-1R and TLR3.
What are the official names of this protein?
Small hydrophobic protein.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: KHSE_SULAC
Sequence: MLIKAYSSSANLGAGFDILALAHNAFEDSVEMEAIPNSTLQVLVTGDGVPNEVDKNSASYAVYRLLSELDVKVKVKMKVIKGIPAGLGLGSSGASAVAAVVGVNNLLKLGLDKQELVRASMIGEIASSGSAHPDNVAASVYGGVVAVLNTEPVTVSPIPVNLNFSLLLFIPVLQLKDKTKKAREMLPRNVELGKMVRNSRYLSSTILGLVKGDRELLRLGLNDEIVEVARSPLFPHYEKLKKISIENNAIGACVSGAGPTIAVFVDEYSDKNKIKKEGLEICETYSQKCLVKEAKIAGGAWVERWN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.