PharMolix/UniProtQA huggingface dataset:
Protein: ATOA_HAEIN
Sequence: MNAKELIARRIAMELHDGDIVNLGIGLPTQVVNYLPDNVNITLQSENGFLGLTAFDPENANSNLVNAGGQPCGIKKGGSTFDSAFSFALIRGGHVDACVLGGLEVDQEANLANWMVPGKMVPGMGGAMDLVTGAKKVIIGMEHCAKSGSSKILKKCTLPLTASKKVAMVVTELAVFNFIEGRLVLKEHAPHVDLETIKAKTEADFIVADDFKEMQISQKGLEL
What is the function of this protein?
Coenzyme A transferase which is involved in short-chain fatty acid degradation and catalyzes the activation of short-chain fatty acids to their respective CoA thiolesters.
What are the official names of this protein?
Acetate CoA-transferase subunit beta, Acetyl-CoA:acetoacetate CoA-transferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: RL22_BAUCH
Sequence: METIAKHRYANSSAQKLRLVINLIRGKEVSKALEILTYTNKKAANLVKKVLESAIANAEHNDGADVDDLKIAKIFVDVGPSIKRIMPRAKGRVDHILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MURB_RHOBA
Sequence: MNDVSSAPSESLTEYFPEDLLHVVRENQPLRETLWLGIGGPARFLAEPVEIDQIEKLYTAAREKQLALRVLGQGSNVLVREAGFDGLVIKLSAPATSGLEIQGQKLVAGAGAKLTHAVIKTVGEGLGGLEHLVGIPGSIGAAVVGNVSAEGRDIGSVVESIEIIDEEGKRKTLTGDEAGFAHRQSTLMGTVVLSVTFNLEPKDVSALTKRMQKLWIHRGQRRPSESNRIAMPFIDPDSISACELINSTGLAGIREGDVSLDSAAPHYLIAHENATSDQCVKLIGRVREQVLMQTGIDLQLNLQIW
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITM_MOUSE
Sequence: MLLRSLRSWAARSPRSVGPGSSGSPGSLDSGAGPLWAPRRAWPPDKDRENDKEKKAVVCIEGNIASGKTTCLEFFSNTTDVEVLMEPVLKWRNVHGHNPLSLMYHDASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRGGKMPEVDYAILSEWFDWIVRNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPMEYLHAIHRLYEEWLVNGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP
What is the function of this protein?
Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix (PubMed:11023833).  In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 and DGUOK (By similarity).
What are the official names of this protein?
Thymidine kinase 2, mitochondrial, 2'-deoxyuridine kinase TK2, Deoxycytidine kinase TK2, Mt-TK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SSPK_BACMK
Sequence: MGRQAEFWSESKNNSKIDSQPKAKSRFASKRPNGTINTHPQERMRAANQQEE
What are the official names of this protein?
Small, acid-soluble spore protein K, SASP K.
What is the protein family that this protein belongs to?
Belongs to the SspK family.
What are the subcellular locations of this protein?
Spore core.
Protein: NOP16_BOTFB
Sequence: MGRELQKKKNRSGNNKIKHKPKSKRINPLGNAIIAANWRQDETLTQNYRRLGLTSRLNTVTGGIEKKTAGSESKTSTANKLAISNAIPKNFAPTEARVERDPETGKIIRVIHDEKKSNPLNDPLNSDDEDGEGFEGFGDEEGSASKNEIVKMLEEQASRAGEKRERQQSEREKEWIEKLVKRWGENYGAMVRDRRLNPMQQTESDIRRRVQKWKDAGGVVTAEA
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CH60_PARPJ
Sequence: MAAKDVVFGDSARAKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKYVASGMNPMDLKRGIDKAVTAAIEELRKISKPCTTNKEIAQVGAISANSDSSIGDRIAEAMDKVGKEGVITVEDGKSLQDELDVVEGMQFDRGYLSPYFINNPDKQVAVLDNPFVLLHDKKVSNIRDLLPVLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVGKENTTIIDGAGEAANIEARVKQVRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRARTAIAGLKGANADQDAGIKIVLRAMEEPLRQIVTNGGEEASVVVAAVAAGQGNYGYNAATGEYVDLVDAGVVDPTKVTRTALQNAASVAGLLLTTDAAVCELPKEDAPMAGGMPGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ECO7I
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDSAESHCLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGHW_SHIFL
Sequence: MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN
What are the official names of this protein?
Uncharacterized protein YghW.
Protein: OCISA_ARATH
Sequence: MAAHNLCFNSAFVCNVHHQKTQHFPCNAVSKTTSTHAVTFHRRSANYRPPLWDHQYLLSLENIYMW
What are the official names of this protein?
Putative inactive (E)-beta-ocimene synthase, chloroplastic, Inactive (E,E)-alpha-farnesene synthase, Inactive terpenoid synthase 2, AtTPS02.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROA_CELJU
Sequence: MEFIDLAPSAHARGAVQLPGSKSISNRTLLLAALAQGETQIRDLLKSDDTDRMLEALTSLGVTLTRTGENDYHLVGTGGSFPHKEADLFLGNAGTAFRPLTAALAFSGGTYKLHGVPRMHERPIGDLVDALRQVGADITYLGQEGFPPLLIKPAHIAAQGSIKIRGDVSSQFLTALLMALPMTGKETHIELVSELISKPYIEITLRLMAQFGVEVQRDGWERFTVPAASGYVSPGTVYVEGDASSASYFLAAGALGGGPVRVQGVGAKSIQGDVAFADALEAIGVTITKGDNWIEASAPQLPLKAFNRDFNHIPDAAMTLAVVALFCDGPSRLTNIASWRVKETDRIAAMATELRKLGAIVEEGEDWLQVTPVPTLNAQVPIDTYDDHRMAMCFSLATFGGVPVRINDPQCTAKTFPTYFDVFSQVVS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_RICCK
Sequence: MTNVITRFAPSPTGFLHIGSARTALFNYLFARHHNGKFLLRIEDTDKERSTNEAVEAIFSGLKWLGLDWDGEVIFQSKRNDLYKETALKLLQAGKAYYCFTSQEEIEKQRQKALENKQYFIFNSDWRDKDPAAYPTDIKPVIRLKTPREGSITIRDTLQGDVVIENSHIDDMVLLRSDGTATYMLAVVVDDHDMGITHIIRGDDHLTNAARQIAIYQACGYAVPSMTHIPLIHGADGAKLSKRHGALGVAAYKDMGYLPESVCNYLLRLGWSHGDDEIISMDQAIKWFNLDSLGKSPAKLDFANMNSLNAHYLRLLDNDSATSKTVERLRQNYNVSKQEVIYINQAIRSLLVRSETLLDLVQLAQIYLVDSPIIYKQDAKEIIENCDKDLIKQVIENLNKLKQFDKESVQNKFKEIATHNGLKLNELMKPVRALITGMTASPSVFEIAEILGKENILKRLKII
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_SORBI
Sequence: MPNILSLTCICFNSVLCPTSFFFAKLPEAYAIFNPIVDVMPVIPVLFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KDPC_BURP6
Sequence: MKSLFRPLIVVFVVLVAVTGLAYPAVMTVFGQAVFPAQANGSLIEKGGRVVGSALIGQQFDAPQYFWGRLSATSPMPYNAAGSGGSNLGPLNPALKDQVKSRLDALKAAGTDLSQPVPVDLVTASASGLDPEISPAAADYQVARVARARKMADADVRRLVADHTSGRQFGVLGEPRVNVLKLNLALDAAQAAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: T1R1_ECOLX
Sequence: MTHQTHTIAESNNFIVLDKYIKAEPTGDSYQSESDLERELIQDLRNQGYEFISVKSQSAMLANVREQLQNLNGVVFNDSEWRRFTEQYLDNPSDGILDKTRKIHIDYICDFIFDDERLENIYLIDKKNLMRNKVQIIQQFEQAGSHANRYDVTILVNGLPLVQIELKKRGVAIREAFNQIHRYSKESFNSENSLFKYLQLFVISNGTDTRYFANTTKRDKNSFDFTMNWAKSDNTLIKDLKDFTATCFQKHTLLNVLVNYSVFDSSQTLLVMRPYQIAATERILWKIKSSFTAKNWSKPESGGYIWHTTGSGKTLTSFKAARLATELDFIDKVFFVVDRKDLDYQTMKEYQRFSPDSVNGSENTAGLKRNLDKDDNKIIVTTIQKLNNLMKAESDLPVYNQQVVFIFDECHRSQFGEAQKNLKKKFKRYYQFGFTGTPIFPENALGSETTASVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKSLETETDEKKLSAAENQQAFLHPMRIQEITQYILNNFRQKTHRTFPGSKGFNAMLAVSSVDAAKAYYATFKRLQEEAANKSATYKPLRIATIFSFAANEEQNAIGEISDETFDTSAMDSSAKEFLDAAIREYNSHFKTNFSTDSNGFQNYYRDLAQRVKNQDIDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLMQAFSRTNRIYDATKTFGNIVTFRDLERSTIDAITLFGDKNTKNVVLEKSYTEYMEGFTDAATGEAKRGFMTVVSELEQRFPDPTSIESEKEKKDFVKLFGEYLRAENILQNYDEFATLKALQQIDLSDPVAVEKFKAEHYVDDEKFAELQTIRLPADRKIQDYRSAYNDIRDWQRREKEAEKKEKSTTDWDDVVFEVDLLKSQEINLDYILGLIFEHNRQNKGKGEMIEEVKRLIRSSLGNRAKEGLVVDFIQQTNLDDLPDKASIIDAFFTFAQREQQREAEALIKEENLNEDAAKRYIRTSLKREYATENGTELNETLPKLSPLNPQYKTKKQAVFRKSSRLLRSLKA
What is the function of this protein?
The restriction (R) subunit of a type I restriction enzyme that recognizes 5'-GAAN(7)RTCG-3' and cleaves a random distance away.  Subunit R is required for both nuclease and ATPase activities, but not for modification (Probable) (PubMed:12654995).  After locating an unmethylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (Probable).  The enzyme undergoes major structural changes to bring the motor domains into contact with DNA, allowing DNA translocation.  This prevents DNA access to the catalytic domains of both the R and M subunits, preventing both restriction and methylation (PubMed:32483229).
What are the official names of this protein?
Type I restriction enzyme EcoR124II endonuclease subunit, EcoR124II, R protein, Type I restriction enzyme EcoR124/3 endonuclease subunit.
What is the protein family that this protein belongs to?
Belongs to the HsdR family.
Protein: PDE1C_RAT
Sequence: MTDTSHKKEGFKKCRSATFSIDGYSFTIVANEAGDKNARPLARFSRSKSQNCLWNSLIDGLTGNVKEKPRPTIVQDTRPPEEILADELPQLDSPEALVKTSFRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIDALKDVDTWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAYRLLQEDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQTGGTGQRRSSLNSINSSDAKRSGVKSSGSEGSAPINNSVIPVDYKSFKATWTEVVQINRERWRAKVPKEEKAKKEAEEKARLAAEEKQKEMEAKSQAEQGTTSKAEKKTSGETKGQVNGTRTSKGDNPRGKNSKGDKAGEKQQNGDLKDGKNKADKKDHSNTGNESKKADGTKKRSHGSPAPSTSSTSRLTLPVIKPPLRHFKRPAYASSSYAPSVPKKTDDHPVRYKMLDQRIKIKKIQNISHHWNKK
What is the function of this protein?
Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.  Has a high affinity for both cAMP and cGMP (PubMed:7568196).  Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials.  Regulates smooth muscle cell proliferation.  Regulates the stability of growth factor receptors, including PDGFRB (By similarity).
What are the official names of this protein?
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, Cam-PDE 1C.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
What are the subcellular locations of this protein?
Lysosome.
Protein: MAP1_KLEOX
Sequence: TVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHNE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: ILVH_METJA
Sequence: MVNIMEHRHVISALVLNKPGVLQRISGLFTRRGFNISSITVGITENPQISRVTIVVNGDDKILEQVIKQLNKLIDVIKVSELEEKKSVQRELCLIKIYAPTESAKSQVIQYTSIFRGNVVDLSPESLIVEITGSEDKINAFIDLVKPLGIKEMARTGITALARGPKILKPKS
What are the official names of this protein?
Probable acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: YHAM_ECOUT
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAISDAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: CSRA_PSET1
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKDVSVHREEIYMRIQAEKSNPEPGNA
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_BEII9
Sequence: MLTKKQSELLRFIHERLKETGVPPSFDEMKEALDLRSKSGIHRLVMALEERGFIRRLPNRARALEVVRLPDAATPPVPPHGRKFSPSVIEGDLGRVRPHTPHTDDEDSELTTVAIPVMGRIAAGTPISALQHRSHTIGLPMDMLPAGEHYALEVRGDSMIDAGILDADTVIIRRQDNAENGDIVVALIDDEEATLKRLRRRGASIALEPANSAYETRIFGPDRVRIQGKLVSLIRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RECR_POLNS
Sequence: MARIEAPQDALGRLIEALRVLPGVGPKSAQRMAFYLLQHDRNGAAVLAQSLGEAVETVGHCACCNTFSETQVCSTCSDERRDPSLLCIVETPADQVMVEQTLSFKGNYFVLMGRLSPLDGMGPNEISFDRLLNRIETPDTGVPIREVVLATNFTSEGEATAHYIGEVLKPKGIKVTRIARGIPVGGELEYVDAGTLARALMDRR
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ADHP_ECOLI
Sequence: MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDFRH
What is the function of this protein?
Preferred specificity is towards 1-propanol.
What are the official names of this protein?
Alcohol dehydrogenase, propanol-preferring.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: PTN_PIG
Sequence: MQTPQFLQQRRKFAAAFLAFIFLLAVVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRALHNADCQKTVTISKPCGKVTKPKPQAESKKKKKEGKKQEKMLD
What is the function of this protein?
Secreted growth factor that mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors.  Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups.  Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration in several tissues namely neuron and bone (By similarity).  Also plays a role in synaptic plasticity and learning-related behavior by inhibiting long-term synaptic potentiation (By similarity).  Binds PTPRZ1, leading to neutralization of the negative charges of the CS chains of PTPRZ1, inducing PTPRZ1 clustering, thereby causing the dimerization and inactivation of its phosphatase activity leading to increased tyrosine phosphorylation of each of the PTPRZ1 substrates like ALK, CTNNB1 or AFAP1L2 in order to activate the PI3K-AKT pathway.  Through PTPRZ1 binding controls oligodendrocyte precursor cell differentiation by enhancing the phosphorylation of AFAP1L2 in order to activate the PI3K-AKT pathway.  Forms a complex with PTPRZ1 and integrin alpha-V/beta-3 (ITGAV:ITGB3) that stimulates endothelial cell migration through SRC dephosphorylation and activation that consequently leads to ITGB3 'Tyr-773' phosphorylation (By similarity).  In adult hippocampus promotes dendritic arborization, spine development, and functional integration and connectivity of newborn granule neurons through ALK by activating AKT signaling pathway (By similarity).  Binds GPC2 and chondroitin sulfate proteoglycans (CSPGs) at the neuron surface, leading to abrogation of binding between PTPRS and CSPGs and neurite outgrowth promotion.  Binds SDC3 and mediates bone formation by recruiting and attaching osteoblasts/osteoblast precursors to the sites for new bone deposition (By similarity).  Binds ALK and promotes cell survival and cell proliferation through MAPK pathway activation (By similarity).  Inhibits proliferation and enhances differentiation of neural stem cells by inhibiting FGF2-induced fibroblast growth factor receptor signaling pathway.  Mediates regulatory mechanisms in normal hemostasis and in hematopoietic regeneration and in maintaining the balance of myeloid and lymphoid regeneration.  In addition may play a role in the female reproductive system, auditory response and the progesterone-induced decidualization pathway (By similarity).
What are the official names of this protein?
Pleiotrophin, PTN, Pleiotrophic factor beta, PTF-beta.
What is the protein family that this protein belongs to?
Belongs to the pleiotrophin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM2D2_DICDI
Sequence: MGHHHHHHGGSGHHHHHHHHGSGHYGGGAVLVTPIVTPVPVVYGSRSSSYCPKSMTVAYVLWFFFGILGFHRLYLGRVGTFFLYFFTAGVFGLGWLFDAFYTHKMVKHYNECEFTKSCVGQSPPATIPIYQSEGAYPTYQQVPQQPPQFYQPQQQQPQYQP
What are the official names of this protein?
TM2 domain-containing protein DDB_G0278163.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KCNF1_MOUSE
Sequence: MDASAEQSLPEPGSQDSVAGEDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVVDSEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSAEGKPGGSRSDLDTLPPEPAAREGPSWGSRLKLSHSDTFIPLLTEEKHHRTRLQSCK
What is the function of this protein?
Putative voltage-gated potassium channel.
What are the official names of this protein?
Potassium voltage-gated channel subfamily F member 1, Voltage-gated potassium channel subunit Kv5.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.