PharMolix/UniProtQA huggingface dataset:
Protein: TENC_BEABA
Sequence: MAAISSPPLTQKALKVASPDTLHLVTDAPLPTLGQDDSVLIRVVCVAINPVDGKSAEMSPTPGATSGTDFAGIVVALHGDAKSRTETADTIKTGDRVMGFVFGNNPHVLGNGAFAEYVTLPRRFLWRVPDHMSLEAAASLPVGVASVGMALHYLRISMSSLLKAVSRSIAAPSASQPHDGAFDSDANVFILVYGGGTSTGAIAIQILKAAGFHPITCCSSESASRAKRLGAVATFDYQSATCGRDIRDYTNDSLTLAIDCLSESASMAICYEAMGSAGGRYVSLDPFPVRGCVRRSIVPDWICSFTQFGQSIPWAPPYNLDERPDDHRLAEEWYHLAQKLLDAELIEAPTLEIRSGGLLHVPEGVAAVKLGQIKRRKLVYHISEEALP
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of tenellin-type 2-pyridones, iron-chelating compounds involved in iron stress tolerance, competition with the natural competitor fungus Metarhizium robertsii and insect hosts infection (PubMed:17216664, PubMed:18266306, PubMed:20575135, PubMed:34903054).  TenC collaborates with the hybrid PKS-NRPS synthetase tenS to catalyze the assembly of the polyketide-amino acid backbone, since tenS lacks a designated enoylreductase (ER) domain (PubMed:18266306, PubMed:34903054).  Upon formation of the polyketide backbone on the thiotemplate of tenS, the triketide is transferred to the NRPS module and linked to tyrosine to produce the pyrrolidine-2-dione intermediates, including pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D (PubMed:18266306, PubMed:34903054).  The pathway begins with the assembly of the polyketide-amino acid backbone by the hybrid PKS-NRPS tenS with the help of the enoyl reductase tenC.  These enzymes catalyze the synthesis of the pyrrolidine-2-dione intermediates pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D.  The cytochrome P450 monooxygenase tenA then catalyzes an oxidative ring expansion of pretenellin A and 14-hydropretellenin A to form the 2-pyridone core, leading to pretenellin B and pyridovericin, respectively.  The cytochrome P450 monooxygenase tenB is then required for the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively.  The UDP-glucosyltransferase GT1 and the methyltransferase MT1, located outside the tenS gene cluster, contribute to the stepwise glycosylation and methylation of 15-HT to obtain the glycoside pyridovericin-N-O-(4-O-methyl-beta-D-glucopyranoside) (PMGP).  Additional related compounds such as 1-O-methyl-15-HT, (8Z)-1-O-methyl-15-HT, and O-methyltenellin A are also produced but the enzymes involved in their biosynthesis have still to be determined (PubMed:34903054).
What are the official names of this protein?
Trans-enoyl reductase tenC, Tenellin biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RL2_CHLTR
Sequence: MFKKFKPVTPGTRQLILPSFDELTTQGELKGSSSRRSVRPNKKLSFFKKSSGGRDNLGHISCRHRGGGVRRHYRVIDFKRNKDGIEAKVASVEYDPNRSAYIALLNYVDGEKRYILAPKGIKRGDRVISGEGSPFKTGCCMTLKSIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAKTAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRRRWKGIRPTVRGTAMNPVDHPHGGGEGRHNGYISQTPWGKVTKGLKTRDKRKSNKWIVKDRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYT_PROMT
Sequence: MPIITLPDGTEKKYDSAVTIDQIASEIGPGLAKAALAGRVNGELIDTCIPITQNSHIQIITSKDDEGLEIIRHSFAHLLGHAVKQLYPEAKMAIGPVIEDGFYYDISYKDTFTPDDLLKIEKRMKELVNRDYSVGVEIVSPEKAKEVFTDRGEIFKLDIVKNIPKNEIIKLYKHQEYIDMCRGPHVPNTRHLRAFKLMKVSGAYWRGDSNNEMLQRIYGTAWKSSKELKEYLSRIEEAEKRDHRKLGKKYSLFHSQEEAPGMVFWHPKGWTIYRILEDFIRETITKYDYQEVKSPQVVDRSLWEKSGHWDKFKEDMFTTTSENREYAIKPMNCPCHIQIFNQGLKSYRDLPIRLSEFGSCHRNEPSGALHGLMRVRNFVQDDAHIFCTDEQIQEEVQNFIDLVFEVYKTFGFDSILIKLSTRPVKRVGSDDIWDKSEKALSEALDSKGLDWSLLPGEGAFYGPKIEFSLKDCLNRVWQCGTIQVDFSMPQRLNASYIDITGRKQTPVMLHRAILGSFERFIGILIENYSGNFPTWLSPIQIMIMGITDRNNEACFTAKDKLVDFGFRAEIDIRNEKVGFKIREHTMQRIPFLIIIGDKEEENSEISVRTREGKDLGNMSIDKFKLIIDESISKKGIQGNQS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_THET2
Sequence: MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFRTQEKRPVVLLAKDTRESSDLLEAALAAGLMSQGVRVEHLGVLPTPGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKLPDEAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLAHAPDLTGLKVGLDLAHGATYRIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGLAFDGDGDRVQFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVLEKLKETGLALGGEPSGHVIFLRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQVLLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPSGTEPVIRVMVEAEEWAEEVARELAERVRALSQEAQAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: IHFA_AZOSB
Sequence: MNVTLTKAELADLLFERVGLNKREAKDMVEGFFEEIRTALERGDSVKLSGFGNFQLRDKPQRPGRNPKTGEEIPITARRVVTFHASQKLKAAVEQLSDASKQP
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL31B_HERAR
Sequence: MKAGIHPEYREVLFHDVSNDFKFITRSTINTREKIEFEGTEYPLVKIEVSSESHPFYTGKHKIVDTAGRVDKFRKKFGTVGSKTQMAE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: INSQ_ECOLI
Sequence: MKRLQAFKFQLRPGGQQECEMRRFAGACRFVFNRALARQNENHEAGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFFRKRAAFPRFKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTGVVKNVTVSQSCGKWYISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKKLARLQRQLSRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTAVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLAYKQLWRGGQVLAVPPAYTSQRCAYCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQEPTEMIQATA
What is the function of this protein?
Not required for transposition of the insertion element.  The corresponding transposase in strains MG1655 and W3110 is a truncated pseudogene (yncK).
What are the official names of this protein?
Putative RNA-guided DNA endonuclease InsQ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.
Protein: CLPP2_MYCPA
Sequence: MSDMRSPSQGLNLTDSVYERLLSERIIFLGSEVNDDVANRLCAQILLLAAEDPTKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFHVIKKEMFRLNAEFTGQSIERIEADSDRDRWFTAQEALEYGFVDHIITRAATITNGEAQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LISMF
Sequence: MVYLQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGGCEFVDIVEDLARDRAKKLFGAEYANVQPHSGAQANMAVYHTVLEPGDTVLGMNLSHGGHLTHGSPVNFSGVLYNFVEYGVREDTKEIDYDIVREAALKHKPKMIVAGASAYPRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRGGMILAKAEWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFTAYCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEVGITVNKNTIPFETESPFVTSGIRVGVAAVTTRGFDEVAIEKVGVLISEVLHNLENEEVLADVKARVATLTNEYPLYPSL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_STRP3
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_LISMO
Sequence: MEEEFPTISLLGIDFNLSNILMITVTCVIVLLIAIICTRNLQRRPTGKQNFIEWVMDFVRGIINSNMDWKTGGRFHVLGITILMFVFVANMLGLPLQIAVNDEVWWRSPTADPIVTLTLAIMVLGLTHYYGIKMRGFKHYFVGTYLSPMKFLFPLKLVEEFANTLTLGLRLYGNIFAGEVLLTIIATQLAHINIFVGVLAIIPAIIWQAFSLFIGAIQAYIFTMLTMVYMSHKVSDEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPA_THISH
Sequence: MFHGSMVALVTPMEADGSVSDASLAELVEFHIQKGTDAIVAVGTTGESATLDFDEHCEVIRKVVDRVAGRIPVIAGTGANSTSEAIELTRCAMQAGADACLLVTPYYNKPTQEGLYLHHKAVAEAVPIPQILYNVPGRTAVDMHNDTVVRLAEISNIVGLKDATGDLDRARDLVARCGGKIDLYSGDDATAMEFLLLGGKGVISVTANVAPAEMHQMCEAAMRGDRAAAEAINARIDLLHRNLFLEANPIPVKWALEQMGLIPPGIRLPLTRLSERFHAPVREALAAAGITLNA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB132_PONPY
Sequence: MKFLLLVLAALRFLTQVIPASAGGSKCVSNTPGYCRTYCHQGETALFMCNASRKCCVSYSFLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 132, Defensin, beta 132.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY_MYCGA
Sequence: MNVAGYISLLVILSLLIGYLFGSIMFADVASMILKRNVRELGSKNPGTTNSFRVFPKKVAIAIGFFEIIKSVIPFSIILLIYKYGLQPELTKLDPSVINKTYYLTYLAPLAAIFGHMYPVYFKFNGGKAVATTAGFVFVVSPWWFLIIALTWWTITLISKYVSLASIVCFIIFLFLPYIPWLDYLWWFSLDKITFLTYQSDWYIIVFFAIANTILSTIIIWKHRGNIVRLINKQENKITKKV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_COXB1
Sequence: MHHRKSGRHLNRTSAHRKAMLRNMAVSLFQHELIKTTLPKAKELRRVVEPLITLAKEDTVANRRLAFNRLRDDAIVTKLFKEIAPRHKERPGGYCRVLKYGFRNGDSAPMAIVELVDREESESSED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ARNC_PSEFS
Sequence: MKPYPIHCVSIVIPVYNEQESLPELLRRTTAACKQLAYEYEIILVDDGSRDNSAQLLEDAAAEDGSNVVAVILNRNYGQHAAIMAGFEQCRGDVVITLDADLQNPPEEIPRLVEQAALGYDVVATVRNNRQDSAFRRWPSRLINLAVQRSTGVAMTDYGCMLRAYRRTIVDAMLACRERSTFIPILANGFARHTTEILVHHAEREHGESKYSAMRLISLMFDLLTCMTTTPLRLLSIVGFSLAALGMLFAFALIVMRLAFGADWAGDGLFVLFAVLFVFTGGQFIGMGLLGEYLGRMYSDVRARPRFFIEKVLRNQPAAPAPVVVVDGLVSSHTSTSADQV
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLN3_YEAST
Sequence: MQDDPENSKLYDLLNSHLDVHGRSNEEPRQTGDSRSQSSGNTGENEEDIAFASGLNGGTFDSMLEALPDDLYFTDFVSPFTAAATTSVTTKTVKDTTPATNHMDDDIAMFDSLATTQPIDIAASNQQNGEIAQLWDFNVDQFNMTPSNSSGSATISAPNSFTSDIPQYNHGSLGNSVSKSSLFPYNSSTSNSNINQPSINNNSNTNAQSHHSFNIYKLQNNNSSSSAMNITNNNNSNNSNIQHPFLKKSDSIGLSSSNTTNSVRKNSLIKPMSSTSLANFKRAASVSSSISNMEPSGQNKKPLIQCFNCKTFKTPLWRRSPEGNTLCNACGLFQKLHGTMRPLSLKSDVIKKRISKKRAKQTDPNIAQNTPSAPATASTSVTTTNAKPIRSRKKSLQQNSLSRVIPEEIIRDNIGNTNNILNVNRGGYNFNSVPSPVLMNSQSYNSSNANFNGASNANLNSNNLMRHNSNTVTPNFRRSSRRSSTSSNTSSSSKSSSRSVVPILPKPSPNSANSQQFNMNMNLMNTTNNVSAGNSVASSPRIISSANFNSNSPLQQNLLSNSFQRQGMNIPRRKMSRNASYSSSFMAASLQQLHEQQQVDVNSNTNTNSNRQNWNSSNSVSTNSRSSNFVSQKPNFDIFNTPVDSPSVSRPSSRKSHTSLLSQQLQNSESNSFISNHKFNNRLSSDSTSPIKYEADVSAGGKISEDNSTKGSSKESSAIADELDWLKFGI
What is the function of this protein?
Positive nitrogen regulatory protein.  Required for the activation of transcription of a number of genes (including the allantoin pathway genes) in response to the replacement of glutamine by glutamate as source of nitrogen.  Binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase.  URE2 may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine.
What are the official names of this protein?
Nitrogen regulatory protein GLN3.
What are the subcellular locations of this protein?
Nucleus.
Protein: HFQ_ECO27
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: G9P_BPM13
Sequence: MSVLVYSFASFVLGWCLRSGITYFTRLMETSS
What is the function of this protein?
May initiate with G7P the virion concomitant assembly-budding process, by interacting with the packaging signal of the viral genome.  The assembly-budding takes place at the host inner membrane.  In turn, G7P and G9P are present at the end of the filamentous virion that emerges first from the bacterial host.
What are the official names of this protein?
Tail virion protein G9P, Coat protein C, polypeptide II, G9P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G9P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=Prior to assembly, is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the tail side of the filamentous virion with G7P (By similarity).
Protein: DGCQ_SHIDS
Sequence: MQHETKMENQSWLKKLARRLGPGHIVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALIAPLDFTSLRDAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELAFLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNT
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.  Involved in the regulation of cellulose production (By similarity).
What are the official names of this protein?
Probable diguanylate cyclase DgcQ, DGC, Cellulose synthesis regulatory protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_NITWN
Sequence: MFNQHSVEIDWGGRPLKLETGKIARQADGAVVATYGETVVLATVVAAKSPREGVDFLPLTVDYQEKTYAAGRIPGGYFKREGRPTEKETLVSRLIDRPVRPLFADGWRNETQVIVTVLSHDMENDPDILAMVAASAALTLSGAPFKGPIGAARVGFINDEYVLNPTLDEIVDTQLDLVVAGTADAVLMVESEAKELSEEIMLKAVMFGHRHFQPVIDAIIELAEKAAKEPRELKVIDDTEIEKEMLGLVEQDLRAAYAIPVKQDRYAAVGKVKEKALAHFFPEGQEPKYDKLRVAGVFKELEAKIVRWNILDTGKRIDGRDVKTVRNIVAEAGVLPRAHGSALFTRGETQAMVVTTLGTGEDEQYIDSLAGTYKETFLLHYNFPPYSVGETGRLGGAKRREIGHGKLAWRAIRPVLPPHHEFPYTIRVVSEITESNGSSSMASVCGASLSLMDAGVPLKRPTAGIAMGLILEGERYAVLSDILGDEDHLGDMDFKVAGTEAGITSLQMDIKIAGITEEIMKVALGQAKDGRIHILGEMSKALDRARAELGEHAPRIETFKIPTDKIREVIGTGGKVIREIVEKTGAKVNIEDDGTVKVASSDGESIKAAIKWIKSIASDPEVGEIYEGTVVKVMEFGAFVNFFGAKDGLVHISQLAAGRVQKTSDVVKEGAKVKVKLLGFDDRGKTRLSMKVVDQETGEDLEAKQKAEGDAPREAAGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB9_XENLA
Sequence: MAISGPLTNYFVQSIISPDTDETPAAKFSAQFPNPRAPAQSEPLDFPSCSFSASWNFLTPHPPVYQPYIQQQQQQEEGAPSAEGRYLRAWLDNGPSLKSEPLLGPPGDKLGPQHYTVASPGGAAANTERSTHSGNFPDTKGTEGTAGETDRTHQNNPSANWLHARSSRKKRCPYSKYQTLELEKEFKFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKLNKDQSKD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B9, XlHbox-6.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
Protein: Y1350_MYCTU
Sequence: MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSYMTGTVLDVTGGRFI
What are the official names of this protein?
Uncharacterized oxidoreductase Rv1350.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SURE_PROM2
Sequence: MKPLNILISNDDGVFAAGIRALAKSAQKRGHKVKVVCPDQERSATGHGLTLQSPLRVEKADELFGQGIEAWGCSGTPADCVKLALSELLDHKPDLVLSGINHGPNLGTDIFCSGTVAAAMEGTLENVPSMAISVASFKWKNFEFAGEIAMNIAEQAINDSWPASLLLNLNIPPCEKNKIKELSWTRLSVRKYKNQFSKREDPRGDDYYWLAGEVVLDLKSKGYGPKNWPSDVSQIQENKISLTPVEPDLFWRGNLDDLPKIDNSFVNPS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_NEIG1
Sequence: MAQKIQSVKGMNDLLPVGQKDFKLTAVFWQAFEDTVNRWTRAYGYQQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLWEKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEAQLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEASQNHYARFKAMLDGLGIQYIENSRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERLLLLVSEYGSLEVNAAPDVYAMHQGEGADLQVMKYAQALRAQGFNVIQHSGYQSLKAQMKKADNSGARFALIVAQDELADGTVTLKDMNGAHGQQTVSATDLTDTLQQWKNA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST45_MYCTU
Sequence: MLSDDELTGLDEFALLAENAEQAGVNGPLPEVERVQAGAISALRWGGSAPRVIFLHGGGQNAHTWDTVIVGLGEPALAVDLPGHGHSAWREDGNYSPQLNSETLAPVLRELAPGAEFVVGMSLGGLTAIRLAAMAPDLVGELVLVDVTPSALQRHAELTAEQRGTVALMHGEREFPSFQAMLDLTIAAAPHRDVKSLRRGVFHNSRRLDNGNWVWRYDAIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELHRRATHFRGVHIVEKSGHSVQSDQPRALIEIVRGVLDTR
What is the function of this protein?
Esterase likely involved in ester/lipid metabolism.  Shows strong substrate selectivity toward short, straight chain alkyl esters with the highest activity toward four atom chains.  The physiological substrate is unknown (PubMed:25354081).  Is able to hydrolyze ester bonds within a wide range of p-nitrophenyl derivatives (C2-C14) in vitro (PubMed:20957207).
What are the official names of this protein?
Esterase Rv0045c.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: EX7S_CUTAK
Sequence: MTDTTPNSAPEEPEITYEAARDELVEIVTRLESGGISLAETMTLWERGEKLADICQSWLNGARARIEAARSDAETAQP
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.