PharMolix/UniProtQA huggingface dataset:
Protein: RL10_STAA1
Sequence: MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL15_SHEPA
Sequence: MRLNTLSPAAGAKSAAKRVGRGIGSGTGKTCGRGHKGQKSRSGGGVRVGFEGGQMPLKIRLPKFGFTSRKALVSAEIRISELAKVNGDVIDLNALKDANLVTRNIQFAKIVLSGTIERPVTVKGLKVTQGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LAM55_STREK
Sequence: MHVPPTDPARSAPPASPHRRRRPKALGLTALAAAMLMAVPTTQAAFGSDVRPAAAQEVVGGGDLGPNVLVFDPSTPDIQGKVDEVFRKQESNQFGTDRYALMFKPGTYNDINAQIGFYTSIAGLGLNPDDTTFNGDVTVDAGWFDGNATQNFWRSAENLALNPVNGTNRWAVSQAAPFRRMHVKGGLNLAPDGYGWASGGYIADSKIDGEVGPYSQQQWYTRDSSVGGWGNGVWNMTFSGVEGAPAQSFPEPPYTTLETTPVSREKPFLYLDGDDYKVFVPAKRTNARGTSWGNGTPEGESLPLDQFYVVKPGATAETINAAVDQGLHLLFTPGVYHVDQPIEIDRANTVALGLGLATIIPDNGVTALKVGDVDGVKVAGLLVDAGPVNSETLVEVGSDGASGDHAANPTSLQDVFVRIGGAGPGKATTSIVVNSNDTIIDHTWVWRADHGEGVGWETNRADYGVHVKGDNVLATGLFVEHFNKYDVQWSGENGKTIFYQNEKAYDAPDQAAIQNGDIKGYAAYKVDDSVTTHEGWGMGSYCYFNVNPDIRQQHGFQAPVKPGVKFHDLLVVSLGGKGQYEHVINDIGDPTSGDTTIPSQVVSFP
What is the function of this protein?
Exo-beta-1,3-glucanase that specifically hydrolyzes laminarin and laminarioligosaccharides, producing glucose and laminaribiose as end products.
What are the official names of this protein?
Exo-beta-1,3-glucanase, Glucan 1,3-beta-glucosidase, Laminarinase, SacteLam55A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 55 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4108_BACHK
Sequence: MGTEFNGLFDEWAHTYDSFVQGEDIQYKEVFAHYEDILEDVVNKSFGNVLEFGVGTGNLTNKLLLAGRTVYGIEPSREMRMIAKEKLPKEFSITEGDFLSFEVPTSIDTIVSTYAFHHLTDDEKNVAIAKYSQLLNKGGKIVFADTIFADQDAYDKTVEAAKQRGFHQLANDLQTEYYTRIPVMQTIFENNGFHVTFTRLNHFVWVMEATKQ
What is the function of this protein?
Could be a S-adenosyl-L-methionine-dependent methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase BT9727_4108.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. YrrT family.
Protein: RL31B_STRPZ
Sequence: MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: KN10C_ARATH
Sequence: MTSHGRKVVRVVARVKPSTDLASTKSISVQKPMGDDSETVTISFGAQFAGSKDSYRLDYCYEENETTGSILTKEIKPLISTVFEGKDANVIAHGARNSGKTHLIQGNERELGLAVLTMSEMLSMAEERGDAIFVSVYEVSQETVYDLLDQEKRVVSVLEGAQGKIQLKGLSQVPVKSLSEFQNLYFGFKKSQKLTSDLPTRSHKGVMIHVTTGNANSGSLGRMNFLDMAGYEDSRKQNSALGPLEIARVNKSIYALQNVMYALNANESHVPYRESKLTRMLKDCLKGSNITLLITCLPREFSQDSFYMLNLASRICLGGNRAITNPTKKKINGLDRSVSLSSAAQRRQTPLTMSAASRKQTVLRGNVTERKTKINTATSAIKARKLFGEANDSVKCKNSSKKVEGKAKMVLKKGISTSKVVLSVQASSPKEEICSSITVTDFQSSLVEEEYSLAFSSSTVAMEPGYSNGASLSSEAIYTTDKETPRKQEEMFAGATHCDDAFVDKAQIVERDENNSVIEEDLTLVIDEGENLDKENNSLLANETASPPLSMRLQELSNNLKSICKFSNQLSVPEKHQTPLTILQAEEASEHSDITAEAAVSIELRTPEKTMPSNIGCSPWKTYSAHSSKLKNSAVGEYLKFINTAGKEDLKKLKGIGDKRAAYIVELREESPFKTLDDLQSIGLSAKQVNGLLKKEIGEIF
What are the official names of this protein?
Kinesin-like protein KIN-10C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-10 subfamily.
Protein: RL2_SYNPW
Sequence: MAIRSFRPYTPGTRTRVVTDFSEVTGRKPERSLVVSKHRRKGRNNRGVITCRHRGGGHKRQYRVVDFRRNKHGVPAKVAAIHYDPHRNARLALLFYTDGEKRYILAPAGVTVGQTVISGPDAPIEDGNAMPLSSVPLGSSVHCVELYAGRGGQMVRTAGASAQVMAKEGDYVALKLPSTEVRLVRRECYATLGEVGNSEIRNTSLGKAGRRRWLGRRPQVRGSVMNPCDHPHGGGEGRAPIGRSGPVTPWGKPALGLKTRKRNKPSNKFVLRKRRKTSKRSRGGRDS
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NUSB_RHOE4
Sequence: MSGTHKKLGARHKARKRAVDFLFEAEARDLDPVALASERSDLSVKDDAVAPVAAYTVTLVSGVAENLDRIDQVISSHLQDWTLERLPAVDRAILRIAVWELFHATDVPPVVAVDEAVELAKQLSTDDSPGFVNGILGQVVLVAPQVRSAAAATSQRAQESDSGTE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PYGB_RAT
Sequence: MAKPLTDSERQKQISVRGIAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQTACDEATYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPNGVLWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLKDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLAEIIVERIGEGFLTDLSQLKKLLSLVDDEAFIRDVAKVKQENKLKFSAQLEKEYKVKINPCSMFDVHVKRIHEYKRQLLNCLHIITLYNRIKKDPTKTFVPRTVMIGGKAAPGYHMAKMIIKLVTSIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVEDVEALDQKGYNAQEFYERLPELRQAVDQISSGFFSPKDPDCFKDVVNMLMYHDRFKVFADYEAYIQCQAQVDHLYRNPKDWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPP
What is the function of this protein?
Glycogen phosphorylase that regulates glycogen mobilization (By similarity).  Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties.
What are the official names of this protein?
Glycogen phosphorylase, brain form.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: EFG_SYNS3
Sequence: MARDFPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTSWNNHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVFGQIKDRLKANAVPIQLPIGAEGELSGIIDLVENKAHIYKDDLGQDIEVTDVPADMKDEADKWRNVLMETIAENDEDLIEKFLESGELSNSDLKRGIRTGVLKHNLVPVLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGLLPNGKEAVRPSDDNAPFSALAFKVMADPYGKLTFVRMYSGVLEKGSYVLNSTKDTKERISRLVVLKADDREEVDALRAGDLGAVLGLKNTTTGDTLCATDDPIVLETLFVPEPVISVAVEPKTKGDMEKLSKALVSLAEEDPTFRVRTDQETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRGSSKGEGKFSRQTGGKGQYGHVVIEMEPGEPESGFEFINKIVGGIVPKEYIKPAEQGMKETCESGVIAGYPLIDVKCTMVDGSYHDVDSSEMAFKIAGSMAFKDAVKKCNPVLLEPMMKVEVEIPEDFLGSVIGDLSSRRGQVEGQSVDDGTSKVSSKVPLAEMFGYATELRSMTQGRGIFSMEFSHYEDVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPIV_ECOLI
Sequence: MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP
What is the function of this protein?
This protein is involved in control of the biosynthesis of isoleucine, leucine, and valine.
What are the official names of this protein?
ilv operon leader peptide, ilvBN operon attenuator peptide.
Protein: GLPK_THEP3
Sequence: MAKYIMAFDQGTTSSRAIIFDRSGKIIASLNQEFKQIYPKAGWVEHDPMEIWGTQIGVAKGVIEKAGINPEDIAAIGITNQRETTVVWDKNTGKPIYNAIVWQCRRTAPICDELKNKGFDKKIREKTGLVVDAYFSGTKIKWILDNVEGAREKAEKGELLFGNIDTWLIWNLTRGKVHVTDYSNASRTMIFNIHELKWDKEILAELNIPEQMLPEVKPSSYVYGYTDKSIFGVEIPIAGDAGDQQAALFGQACFKPGMAKNTYGTGCFMLMNTGEKAVPSNTGLLTTIAWGIDGKVEYALEGSIFIAGAAIQWLRDELRIIDNSPQSEEYAMKVEDTNGVYVVPAFVGLGAPYWDMYARGTIVGLTRGAKREHIIRATLESIAYQTRDVLEAMQEDSGIRLQALKVDGGASANNFLMQFQSDILGVPVDRPQVIETTALGASYLAGLAVGFWNSREEIEKNWNVDKHFEPAMDNEKREKLYKGWKKAVERAMKWAEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SYD_SHIF8
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLSAEIIEAILDRTAAQDGDMIFFGADNKKIVADGMGALLLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STRT2
Sequence: MIQQESRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVATVKQATPGGAVKKGDVVKAVIVRTKTGARRSDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMRIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RM04_ASPCL
Sequence: MHRQSIVRLTRQCGGLPLVELPPPYLAPSLHFSLIRSPVQCSSFSSTAVAAGRERDLSKSRGVSAIHRTGPKFRLGVSKYPLPKPVSPDALEKRYPTPDHGLWGFFPKDKSALSTPEYDVAHGRSWSIQELREKSWDDLHSLWWVCVKERNRIATSNLERQRLKAGYGEWEANDRDKVIRVTQKSIKHVLRERWYAWEDAQRLYKNGYRPQDEDNQE
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPE_MAGSA
Sequence: MAEKIQFELVSPAKLLVSSKVDMVVVPGAEGDFGALALHAPMITTVRPGVIDIHDGGKVSSSVFVAGGFAEVNEERITVLAEEAIPVGELTAEMAEARKKAAKEALDDAKSDRDKAHAGRLMLVAEAMAAAVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MIAA_AZOSB
Sequence: MSSPESALPPALLLLGPTASGKTASALALAATLPVEIISVDSALVYRDMDIGTAKPSAAEQAVCPHHLIDVVSPEEAYSAARFCAEASVLMRDISARGRIPLLAGGTMLYFKALRDGLSDLPPADPVLRRAIEERAAAAGWPALHAELARLDPDAAARLEPTDAQRIQRALEIVTLSGAPLAASYARREDAPLPCRLLPIALAPSDRAVLHARIEQRFDQMLAAGLVDEVAALRERYVLQPQMASMRCVGYRQAWEFLDGEIDRATLRFKGIAATRQLAKRQLTWQRQFRDQWPELVELDCLAPDLPQHVRDTALRLLGA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RUN3A_DANRE
Sequence: MEQSFMQSAMAMGAQSKKGFSRSIAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFINFAAILEHILSHRFKGSGSWFDGQRSFWDFIRLACSKVPNNCISSIENMENINSSRAKGRAWLRVALMEKRLSEYIATALRDSRTTRRFYDEGAIMLREEATVLTGMLIGLGAIDFSFCLKGEALDGKSEAVIDYTPYLKFTQSYDYLSDDEDGQSVDSSNSDDSVEHPYIPLVTDEESWRNKCRKMEQRFKIVNAQKGYLEELVRLRESQLKNVEMENKKLTAGLEELQQQSQKEKRELENIILELQEQLTSLIPGESHPLSKDLSIPLVNQWPSLQNYNNQEDSKLYHRGSFPSPEPHISLTTGSQRTERKQNGKSWCTAEKDYTPSMLGLCGSMSSLPSCKSLPSLRSTECLVNISAEPSPALTPS
What are the official names of this protein?
RUN domain-containing protein 3A, Rap2-interacting protein, Rap2ip.
What is the protein family that this protein belongs to?
Belongs to the RUNDC3 family.
Protein: RL6_BUCAI
Sequence: MSRVAKCPIVIPSGVNVQLDLQDISIKGKYGHLSRTIHQSVKIEFLNNQIIFSPRLGFSNGWAQAGTSRALVNSMIIGVSEKFSKKLQLSGVGYRVSITKDNIINMSLGYSHIITYHLPKGINAENLSPTEIIIQGIDKQLVGQIAANLRSYRTPEPYKGKGIRYSNEVVRIKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PLPP4_MOUSE
Sequence: MRELAIEIGVRALLFGVFVFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIRRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMRCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPTSLKKEERPTADSAPSLPLEGITEGPV
What is the function of this protein?
Magnesium-independent phospholipid phosphatase with broad substrate specificity.  Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate.  Phospholipid phosphatases are involved in both the synthesis of lipids and the degradation or generation of lipid-signaling molecules like diacylglycerol.
What are the official names of this protein?
Phospholipid phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RCA_PINPS
Sequence: SFQCELVFAK
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic, RA, RuBisCO activase, Water stress-responsive protein 4.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: MURI_STAAT
Sequence: MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RPOB_LACAC
Sequence: MLNGHVVNYGKHRTRRSFSRIKEVLKLPNLTDVQTESYKWFLDKGIKEVFDDIMPISDFSGKLSLEYVGYKLQKPKYTVDEARDHDATYAAPMHVTLKLTNQETGEIKTQDVFFGDLPLMTESGSFIVNGAERVIVSQLVRSPGVYYTGDYDKNGRQIFGTTVIPNRGAWLEYETDAKNVSYVRVDRTRKLPLTVLIRAMGIGSDSEIIEMFGQSDTLQFTLDKDVHKNPADSRVAEALKDIYERLRPGEPKTTDSSRSLLYARFFDPRRYDLAPVGRYKINKKLSLKNRLYGQTLAETLADPDTGEIIVKKDTVVTHEIMDKLAPYLDRDDFKMVTYQPSKEGVLPDPITVQEIKVYSKVDPEREVKLMSNGHIDADVKHLTPADVLASINYFFALQDKIGTTDDIDHLGNRRIRRVGELLQNQFRIGLARMERVVRERMSIQDPSTVTPQQLINIRPIVASIKEFFGSSQLSQFMDQHNPLGELTHKRRMSALGPGGLTRDRAGYEVRDVHYTHYGRLCPIETPEGPNIGLINSLASYAIINKYGFIETPYRRVSWDTHKVTDKIDYLTADEEDNYIIAGANTPLNDDGSFKEDIILARQKEDNVEVTPDKIDYMDVIPKQVVSVASACIPFLENDDSNRALMGANQQRQAAPLINPHSSLVGTGMEYRAAHDSGAALIAKAAGTVEYVDADEIRIRREDGTLDKYTLEKYRRSNNSKSYNQTPNVKLGDHVDESDVIANGPTMDHGELALGQNPLIAFMTWNMYNYEDAIMLSERLVKDDVYTSISIEDYESEARDTKLGPEEITRELPNIGEDALKDLDADGIVRVGAEVHDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVQDVKVYTREAGDELSPGVNTMVRVYIAQKRKIQVGDKMSGRHGNKGTVAAVMPEEDMPYLPDGTPVDICLNPMGVPSRMNIGQLLELHLGAAARQLGIHVATPVFDGANENDVWDTVRQAGMDKDGKTVIYDGRTGEPFHNRVSVGVMHYLKLTHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKAYEAIVKGERIPKPGVPESFRVLVKELQSLGLDIRVLDMDHNEIELRDMDEDSSEHLNIDTLSRMAEEQEKKKLAEETGKSENKEDSNETADKPVAPADESDGKVSK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PKHN1_HUMAN
Sequence: MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPGTDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDRWLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGGPEASGGLVQWI
What is the function of this protein?
Controls the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR, in cooperation with the RNA stabilizer ELAVL1 (PubMed:29180010).  Decreases the stability of the leptin mRNA by antagonizing the function of ELAVL1 by inducing its atypical recruitment from the nucleus to the cytosol (By similarity).  Binds to cardiolipin (CL), phosphatidic acid (PA), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidylserine (PS) (PubMed:18191643).  Promotes apoptosis by enhancing BAX-BAK hetero-oligomerization via interaction with BID in colon cancer cells (PubMed:29531808) (By similarity).
What are the official names of this protein?
Pleckstrin homology domain-containing family N member 1, PH domain-containing family N member 1, Cardiolipin and phosphatidic acid-binding protein.
Protein: ACEK_BORPA
Sequence: MIYSGDVQRIEPAPVAGPAPLDVAHLILAGFDRHYALFRYSAQRAKSLFESGDWHGMQRLSRERIEYYDMRVRECATQLDSALRGSDARTADGSRANGSAALSEAQTAFWQAVKQEFVGLLADHRQPECAETFFNSVSCRILHRDYFHNDFLFVRPAIATDYLDSRIPSYRVYYPVAEGLHKSLIRMVADFGLAVPYADLPRDAGPRLASDCQIQVLGSLFFRNTGAYIVGRLINQGTVYPFAVALRRNPAGQVCLDALLLGTDDLSTLFSFTRAYFLVDMETPAAVVNFLASLLPRKPKAELYTMLGLQKQGKTLFYRDFLHHLTHSRDAFDIAPGIRGMVMCVFTLPSYPYVFKLIKDRIDKDGMDHATVRRKYQMVKLHDRVGRMADTWEYSQVALPRSRFAPRLLEELRRLVPSLIEENGDTVVIRHVYIERRMMPLNLYLRHASDPLLEVAVREYGDAIRQLATANIFPGDMLYKNFGVTRLGRVVFYDYDEIQRMTEMNFRAIPPAPNEEAELSSEPWYAVGPNDVFPEEFGRFLLGDPRVRQAFLRHHADLLAPQWWQACRARVAQGRIEEFFPYDTDRRLHPQAAPPPRAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_ECOLI
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, Cell division protein FtsJ, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCRA_ENTFL
Sequence: MMIMEYVIETENLTKQYGETTVVNKINLHVPKGKIYGLLGRNGAGKTTAMKMMLQLAFPTDGTVRLFGTNYKENIHTLYSKVGSIIETPGFYSNLTGYENLQILAKLRGGVSKSGVEKALEVVGLHKEKRKVFSDYSLGMKQRLGIAAAIMHEPELLILDEPINGLDPIGISEIRSFLSKLSHENGTTIFISSHVLSEIEQIADVIGVMHEGHLVEEVNISELHKRNRKYTEFDVSDGKIAAKILESSYHMTDFTVQDGTIRIYDFSQSVGEINREFARNGLLITRINDSEENLEDYFSKLIGGGGIA
What is the function of this protein?
Essential for high-level bacitracin resistance (PubMed:15388429).  Part of the ABC transporter complex BcrAB.  Probably responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Bacitracin transport ATP-binding protein BcrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SSTT_SHEAM
Sequence: MSTEKSLLANAAGGSLVLQIFVGIIAGVALAGFSPEAANQVAFLGDLFVGALKAIAPVLVFVLVASSIANQVSGAQTNMRPIILLYLVGTFAAALTAVLMSFAFPTSLVLIDAAAGANPPEGIGQVLNTLLFKLVDNPVNALINANYIGLLAWGVGLGIALRHASTSTKNMLHDVSHGVSQLVRFVICLAPIGIFGLVAATIAQTGFEALAAYAQLLGVLLGAMAVIAFVVNPLIVFLKIRRNPYPLVFKCLRESGVTAFFTRSSAANIPVNMALCERLKLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLATALLLSVIAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFTIGVIQDSAETALNSSTDVLFTAAACEAAERKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.