PharMolix/UniProtQA huggingface dataset:
Protein: AGC1_ASHGO
Sequence: MELSSASTVKKKRQLAIFNAYATPLRQDERRLRASYEHGGVVGGHVASNEKVLLFDDFVDLISNSRSFYSKFTDHCFNLNQIPNTVFGCIFFAIDENNKGYLNVNDWFYFNNVLEYDNYHFIILYEFFRKFDAARERAYGPSVKSINYGNRFLSFDELYLDLEQFQATLRLLHSCVRDDFIVNNKLFLDWKQFRWLKWYQFYPRGLLQNGPHITLNSLISIVQNDLKSEKLLLGFHCLSQLDHRTNSMTISKNQLVYLMRLFYSHKIPADIFNSLNMSTLSCAKCDNNHINYNVFRDLFYLIQNFDLLNQIVHRYAEVHKFSDRDVREQHISRKDLLRFMNTEYNKINNIIEFSPAQISLLFSIVTNSKKLNYLNNARQNNPELSYHHRDSEIDSFIHNEYINGNAASSLHNESLEKFNDDFENIIQADAGDTKQQISSTDWRSVFSWSSFLSSFEWLHFKKRKSVQTNGLSDEYVNEALTLEDIMKIVNPNYLNDLVHHMELRRIESESRSSNLYFYPIFDSIYNFTLGSVAGCIGAMVVYPIDMVKTRMQAQRDFSKYKNSIDCLLKILSKEGVRGLYSGLGPQLIGVAPEKAIKLTVNDHMRATLAGRDGKLSLPCEIISGATAGACQVVFTNPLEIVKIRLQVKSDYVADAARNSVNAISVIKNLGLIGLYRGAGACLLRDIPFSAIYFPTYAHIKSNVFNFDPKDSDKRNKLNTWQLLVSGGLAGMPAAFLTTPFDVIKTRLQIDPKKGESVYNGIWDAARTILKEEGIKSFFKGGPARVLRSSPQFGFTLAAYEIFHNLFPAPRYDDSTTHRPTREPVGALAPINKTVSAFFPDQLEPHVGNNKWASRLYGPNIDPYSSSFLNYYYKSCQVAKAFMDLDYNFAHFDFNTYQQFHDELNAMKNKKH
What is the function of this protein?
Calcium-dependent mitochondrial aspartate and glutamate carrier.  Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis.  Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids (By similarity).
What are the official names of this protein?
Mitochondrial aspartate-glutamate transporter AGC1, Aspartate-glutamate carrier 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS11_MYCPA
Sequence: MPPAKKAAAAPKKGQKTRRREKKNVPHGAAHIKSTFNNTIVTITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVRKVDVFVKGPGSGRETAIRSLQAAGLEVGAISDVTPQPHNGVRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PPCE_BOVIN
Sequence: MLSFQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCNFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVCLDPNTLSDDGTVALRGYAFSEDGEYVAYGLSASGSDWVTIKFMKVDGAKELADVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLCYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLHQEPNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESRWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDMATGALLKTFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVCRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDNKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSPKFIATLQHLVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIQ
What is the function of this protein?
Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
What are the official names of this protein?
Prolyl endopeptidase, PE, Post-proline cleaving enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_RHOCS
Sequence: MTTAVLEALFAELRFDADGLVPAIAQQHDTGEVLMLAWMNRESIKETLAGGRVVYWSRSRRALWRKGDTSGQIQHLKELRLDCDGDALLLLVDQVGVACHTGRRNCFYRAVRDGTLAVIADVEVPAEELYGKG
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_SYMTH
Sequence: MAEFRIDPEMELPVLPSRARADVSRKPEWLKINLRTDAEFVELKRLMRGQGLHTVCEEARCPNIFECWNRRTATFMILGDICTRNCGFCAVRSGVPTGLDLAEPERVADACVQLGLRHVVVTSVARDDLSDGGASIFAETIRAIRRKNPFTGVEVLIPDFGGNWDALAVVMDAEPDVLNHNIETVRRLSDRVRSRAKYDRSLELLRRAKEMKPHVSTKSSIMVGLGETMQELYEAMDDLRAAGVDIVTFGQYLRPTARHLAVEKFYTPAEFEHLREEALKRGFAHCESGPLVRSSYHADEQSAQAVARRTGAGRAAQTGD
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_SALPB
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PSEA8
Sequence: MSACQSPIIVALDFPTREAALALADQLDPKLCRVKVGKELFTSCAAGIVETLRGKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACRETLEAFSGPRPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAQKAGMDGLVCSAQEAPALKAAHPGLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAIVAELG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: HXABB_DANRE
Sequence: MMDFDERVPVGSNMYLPGCTYYVSGTDFSSLPPFLPQTPSSCPMTYSYSTSSLPQVQSVREVSFRDYAIDTSSKWHSRGNLPHCYATEDMVHRECLSNPGTLGDMLSKNNSVLYHSNSSHTSNVYGSVGRNGVLPQAFDQFFETAYGNVENQPTEHPVDRATSKAPPPAESGSDSCRGTDETERCEETSSPEPSSGNNEDKFSGSSNGQKTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYYTTNPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A11b, Hox-A11.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHER3_PSEPK
Sequence: MTSERNTDIEIRLLIEAIYLKYSYDFRNYSGASIKRRILHALRQFDCLTVSALQERVLHDPGMFMQLLQYLTIPVSEMFRDPDHFLAVRNEVVPLLRTWPSIKVWIAGCSTGEEVYSMAILLREEGLLERTIIYATDINPHSLDRAKQGIYSMQSMREYEENYRLAGGRRDFAEYYTAAYGNAIMDSSLRDNVTFADHSLATDSVFSETQLVSCRNVLIYFNKDLQDRALGLFHESLCHRGFLVLGSKESVDFSAYSDRFEPLVKPQRIFRKS
What are the official names of this protein?
Putative methyltransferase Cher3.
Protein: PPA1_PICPA
Sequence: MFSPILSLEIILALATLQSVFAVELQHVLGVNDRPYPQRTDDQYNILRHLGGLGPYIGYNGWGIAAESEIESCTIDQAHLLMRHGERYPSTNVGKQLEALYQKLLDADVEVPTGPLSFFQDYDYFVSDAAWYEQETTKGFYSGLNTAFDFGTTLRERYDHLINTSEEGKKLSVWAGSQERVVDTAKYFAQGFMKSNYTDMVEVVALEEEKSQGLNSLTARISCPNYNSHIYKDGDFPNDIAEREADRLNTLSPGFNITADDIPTIALYCGFELNVRGESSFCDVLSREALLYTAYLRDLGWYYNVGNGNPLGKTIGYVYANATRQLLENTEADPRDYPLYFSFSHDTDLLQVFTSLGLFNVTDLPLDQIQFQTSFKSTEIVPMGARLLTERLLCTVEGEEKYYVRTILNDAVFPLSDCSSGPGFSCPLNDYVSRLEALNEDSDFAENCGVPKNASYPLELSFFWDDLS
What are the official names of this protein?
Acid phosphatase PHO1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
Protein: MSHB_CORJK
Sequence: MTSTPAEAKITVMAVHAHPDDETLWTGLALAKARRLGHDVAVVTCTLGEEGEVIGEKYQALVDAQQYEQGTGMLGGYRIAELQRALGALGVQHGPNFLGGCGTWRDSGMEGSESIRHPRAFAREVEPAQDLLDAQVEQLIQQIQSIRPEVILTYAADGGYGHPDHKQAHRIVHEAVQRLSGASAEGAGADVFVPSQVLWCVTEDEKFAKGMQGLEDDPTAVPEGWTLPAAGEIATVPSAEVDLVIHGSAEDVAAKQAAMRAHATQIWVADGTASDVNAQVRESNPPAPSATTLFCLSNLITQPLLDSESYRLGWTAPGVPEDFFARALAEQMV
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: FIMB_ECOLI
Sequence: MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIHGFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEVQALKNWLSIRTSYPHAESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRLIQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL
What is the function of this protein?
FimB is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E. coli.  These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, FimA.  FimB switches FimA on.
What are the official names of this protein?
Type 1 fimbriae regulatory protein FimB.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: LPXB_CITK8
Sequence: MAEQRPLTIALVAGETSGDILGAGLIRALKARVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTRRFTELQPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRSTNMVLAFLPFEKAFYDKFNVPCRFIGHTMADAMPLDPDKNAARDVLGISHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEVVVPLVNAKRREQFERIKAEVAPELSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPHALAEALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAADAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: HUTH_BARHE
Sequence: MTIVLNPGKVTLSQLEAVYWNGEVSKLHHDTHFAIKKGAERIAKIAAGSEPVYGINTGFGKLASIKIDADNVVVLQRNLILSHCCGVGVPLAENIVRLMMTLKLISLGRGASGVRLELVQLLENMLANGVIPVIPEKGSVGASGDLAPLAHMAAVMMGEGEAFFQNIRMSGIAALEKAGLCPITLEAKEGLALINGTQTSTALALAGLFRGYRALCGGLLAGALTTDALMGSTAPFHPDIHILRGHYGQIVVSETLEKLVKDSGIRAAHLRDDDRVQDPYCIRCQPQVMGACFDLLIAAAKTLIIEANAVTDNPLILSDDTVVSGGNFHAEPVAFAADQIALALCEIGSISQRRIALMVDPAVSYGLPAFLAKNAGLNSGFMIAEVTAAALMSENKQMAHPASVDSTPTSANQEDHVSMACHGARRLLAMSENLFTIIGIETLVAAQGIEYRAPLKTSSLLQSVMEYLRKNIDTLKGDRYLASDLHKAHILVSEGRLLSVLSETIFPQLKPK
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_PROM9
Sequence: MSSYPPHVIVLIGATASGKTELAIEIAEYFKTRIHNIDSRQIYKSMDIGTAKPSENQQKKIKHFLIDIEEPINPINVKQFQEIAQKSIQKEIKQNNLPLLVGGSGLYMNAITKGFFVPDVPPQNNLREQLEELGQKECWELLKNCDPISAKKINLADQIRTIRALEVFYVTGKPLSSQKVQKPPQWKILELGLNRDNLKERISRRTKNMFLSGIIEETKNLISRYGSDLPILETIGYREAKDVLNNNLPIDKAIELTNIKTNQFAKRQKTWFRNKNNPIWLNNKNLLKDAIIKIESFLD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPB_METC4
Sequence: MTLNPAPNSFRTGPDERGRFGIFGGRFVAETLMPLILDLEKAYADAKADPSFKADMESYGTHYIGRPSPLYFAERLTEHLRAQAPAGQGAKIFFKREELNHTGSHKVNNVLGQILLARRMGKPRIIAETGAGQHGVATATLCARFGLKCVVYMGAVDVERQAPNVFRMKMLGAEVIPVQSGTRTLKDAMNEALRDWVTNVSDTFYCIGTVAGPHPYPAMVRDFQSVIGIETKQQMLEMEGRLPDSLIACIGGGSNAMGLFHPFLDDRDVEIYGVEAAGHGVQSGLHAASLTGGRPGVLHGNRTYLLMNEDGQIADAHSISAGLDYPGIGPEHAWLHEMGRVTYLSATDAETLEAFKLCSMLEGIIPALEPAHALSKVMELAPTKPAEHLMVLNLSGRGDKDIPQVAQIFGQTL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SNXAB_DANRE
Sequence: MQEFTGVWVRDPRIQKEDFWHAFMDYEVCIHTNSLAFTKKSSCVRRRFSEFVWLRKKLQENALLITHIPKLPPKNPFFSLNNAKEIGARMEGLRKFLEAVVHSAVLLSDSCLHLFLQSQLSLKKIEACAEGRTRYTVSEAIHSFSSGHKRFDSLCEENMEEEQCVQCESE
What is the function of this protein?
Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes.
What are the official names of this protein?
Sorting nexin-10B.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPXD_METFK
Sequence: MNKSYSLREIVSTLGGELLGKDDVLISRVASLANAQPGQISFLTDSKYRSVLATTNASAVILTPQNRDITALPRILTDNPYAYFAKVSDLLNPKPEYVAGVDDTAVIAPSAQVPASCTIMAKAVVGANVVLGEHVVVHPGCVIGEGVEIGAHSVLHANVTIYHHCMIGERCNIFSGSVIGGDGFGYAPEEGRWVKIPQVGRVVIEHDVDIGANTTIDRGAIDDTIIHEGCKIDNLVQIGHNCRIGAHSVIAGCVGIAGSAVLGKHCRIGGAAMILGHLEIADGVTVSPGSMITRSLMKAGTYTALMPFQSHDEWLRTAAGIRRLGELAERVKQLEKQLAPQQVSGIQRDK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RF1_HALLT
Sequence: MSSDAQEASDDRRKYEFRKVIEELRDFEGSGTQLVTIYIPEDRQVSDVVAHVTQEHSEASNIKSKQTRTAVQDALTSIKDRLRYYDTFPPENGMVIFSGAIDAGGGQTDMVTRTLESPPQPVESFRYHCDSAFLTEPLEHMLEDSGLFGLIVLDRREANVGWLKGKRVEPVKSASSLVPGKQRKGGQSAQRFARLRLEAIDNFYQEVAGMADDLFVDKRHELDGILVGGPSPTKDEFLDGDYLHHELQDKVLGKFDVAYTDESGLKDLVDNASEALADQEIVEDKRHMDEFFENLHTGEEATYGFDQTRRNLIMGSVDRLLISEDLRSDVVVYECPNGHEEYEVVDSRHSTPSHECSECGEEADVDEREDVIEHLMSIAEQRGTDTKFISTDFEKGEQLLDAFGGIAGILRYSTGV
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STRPJ
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_AYWBP
Sequence: MNTYLDLCRFIFQKGSFRKDRTNTGTKSVFGYQMRFNLEEGFPLLTTKKMNLRSIIHELLWFLKGDTNIFYLVQNNVNIWNEWPYQKYQQSDFFQNETLKEFVKKIKNDPLFATKHGNLGPVYGKQWRDFNGVDQIKFLISEIKANPNSRRLILNSWNPSLLNQMALPPCHVLIQFYVHQGKLSLQLYQRSGDVFLGIPFNIASYSLLLMMVAQVTNLQPYEFIHTLGDAHIYSNHITQVQTQIQRTPKKLPQMILNPDIKNIDDFKFIDFILKNYQCDGILKGDIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: API3_ASCSU
Sequence: MHVWLILSLASLWTSSIAYSQFLFSMSTGPFICTVKDNQVFVANLPWTMLEGDDIQVGKEFAARVEDCTNVKHDMAPTCTKPPPFCGPQDMKMFNFVGCSVLGNKLFIDQKYVRDLTAKDHAEVQTFREKIAAFEEQQENQPPSSGMPHGAVPAGGLSPPPPPSFCTVQ
What is the function of this protein?
This is an inhibitor of the aspartic protease pepsin.
What are the official names of this protein?
Major pepsin inhibitor 3, PI-3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I33 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FIXA_SHIFL
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVDAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: LEU1_GLOC7
Sequence: MSNQPNRIIIFDTTLRDGEQSPGATLNGDEKLTVARALARLGVDVIEAGFPYASPGDFEAVQQIAKVVGVEGGPSICGLARATKADIAKAAEALKPAAKPRIHTFLATSDIHLAYKLKKTRQEVLEIVPEMVAYAKSFVDDVEFSPEDAGRSDPEFLYQVLERAIAAGATTVNIPDTVGYLTPSEFGQLIRGIKENVPNIDQAIISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNAALEELVMALHVRRQYYNPFLGRPVDSTEPLTNINTKEIYKTSRLVSNLTGMAVQPNKAIVGANAFAHESGIHQDGVLKNKLTYEIMDAESIGLTNNQIVLGKLSGRHAFSTRLKELGFELSETDLNKAFLRFKEVADKKKEITDWDLEAIVNDEIQQAPEVFRLELVQVSCGDQARPTATVILRGPEGQELMDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVKSVTAGIDAMGEVTIRLKYENRIFSGHAANTDIIVASARAYISALNRLYAAIEQEKAEKEKAAVTSAS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PYRI_AERHH
Sequence: MSEKNQLQVEAIRHGSVIDHVPAGQGIKILKLFQLIETQERITVGFNLKSGALGKKDLIKIENTRLTEQQANQLALFAPKATVNIIEDFAVVKKHQLELPEFIAGVFHCPNSNCISHNEPVDSYFRVREVKGVVRMKCKYCEKSFTQDIVSERY
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: WK452_ORYSI
Sequence: MTSSMSPAPAPAYAQVMEDMEKGKELAAQLQGLLRDSPEAGRFVDQILHTFSRAMRALDKAAVSAAGGEGSEVQSEVTCGGGASAGGKRKAPAANRKANCRRRTQQSSGNTVVVKNLDDGQAWRKYGQKEIQNSKHPKAYFRCTHKYDQMCTAQRQVQRCDDDPASYRVTYIGEHTCRDPATAPIIAAHVIHQVAAGDDDDGCGGLHAGSRLISFVAAPAAPVDAAAAPTTSTITTVTAPGPLLQPLKVEGGIGSSDQEEVLSSLTPGSSAARGGGVAGPFGPDQGDVTSSLHWSYDAVAGMEFFKNDEVVFDLDDIMGLSF
What is the function of this protein?
Transcriptional activator involved in defense responses against pathogens (PubMed:19700558).  Acts as positive regulator of defense responses against the rice blast fungus Magnaporthe oryzae (PubMed:19700558).  Acts as positive regulator of defense responses against the bacterial blight Xanthomonas oryzae pv oryzae (Xoo) and the bacterial streak Xanthomonas oryzae pv oryzicola (Xoc) (PubMed:19700558).  Acts as positive regulator of abscisic acid (ABA) signaling that suppresses growth of seedlings (PubMed:21725029).  Acts as negative regulator of salt stress response (PubMed:21725029).  Acts as negative regulator of cold stress response (PubMed:21725029).  Acts as negative regulator of drought stress response (PubMed:21725029).
What are the official names of this protein?
Transcription factor WRKY45-2, OsWRKY45-2, OsWRKY45, WRKY transcription factor 45-2.
What is the protein family that this protein belongs to?
Belongs to the WRKY group III family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BETL1_ARATH
Sequence: MASNPHRSGAGGSLYGGAAPYRSREGLSTRNAAGSEEIQLRIDPMHSDLDDEITGLHGQVRQLKNIAQEIGSEAKFQRDFLDELQMTLIRAQAGVKNNIRKLNMSIIRSGNNHIMHVVLFALLVFFVLYIWSKMFKR
What is the function of this protein?
Required for vesicular transport from the ER to the Golgi complex.  Functions as a SNARE associated with ER-derived vesicles (By similarity).
What are the official names of this protein?
Bet1-like protein At4g14600.
What is the protein family that this protein belongs to?
Belongs to the BET1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: INA17_LACTC
Sequence: MLNPRPCVPRLLSAVARCHKPYSTSIKSLEDLAKLKSLDDVDPDLVRKLINERTNELNSQAELAMLKQMQSQENQQQQQALKKFVRPMWIFLLMSSFFYLTGHYIWWKLEYDEREIELHKQVQALRQELDSAIAAKHSGKEPALSGAGAKKPKRWYLAWLW
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DEOC_STRZP
Sequence: MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVEHAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNLALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGGATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADGDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECH19_MYCS2
Sequence: MSETGKGPDALVEQRGHTLIVTLNRPEARNALSGEMLSIMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKGADKKPPGDSFKDGSYDPSKIPGLLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIACDMLLTGRHITAAEAKEYGLIGYVVPDGTALDKALEIAETINNNGPLAVQAILKTIRETEGMHEDEAFGPDTRNGIPVFLSEDAKEGPRAFKEKRAPNFQMK
What is the function of this protein?
Degradation of the cholesterol side chain involves 3 multistep beta-oxidation cycles, this may be involved in the second cycle.  Hydrates 3-OCDO-CoA ((22E)-3-oxo-chol-4,22-dien-24-oyl-CoA) to make 22-HOCO-CoA (22-hydroxy-3-oxo-cholest-4-en-24-oyl-CoA).  Not active on (E)-3-OCDS-CoA ((E)-3-oxocholest- 4,24-dien-26-oyl-CoA) or 3-OPDC-CoA (3-oxo-4,17-pregnadiene-20-carboxyl-CoA).  Hydrates the same substrate as ChsH3 (AC I7GCU8), but the 2 enzymes make different stereoisomers of the product.
What are the official names of this protein?
Enoyl-CoA hydratase EchA19.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.