PharMolix/UniProtQA huggingface dataset:
Protein: PYRR_CLOB8
Sequence: MKLKSVLLDEKAVNRTLIRISHEIIERNKGIDELVLLGIKTRGYPLAKRIASYIKGIEGVDVPVGSVDITLYRDDLTKISEDLEIKNLDLGLEIKDKKIIIIDDVLYTCRTARAAIDAIMDVNRPRGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVIAVSLKEIDGEDSVKIFDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: DXR_CORGB
Sequence: MGVVTKKILILGSTGSIGTQALDVIADNSDKFEVVGIAAGGSQPDLVISQAQQLGLAADKVAVADAQAAAVVSKALGGEIISGTDAAKILVETTKADTVLNALVGSLGLAATLATLESGAHLALANKESLVAGGEFVTSKAKLGQIIPVDSEHSAMAQCLRSGTRDEVARIVLTASGGPFRGWTREKMWEVTPEQAAAHPTWAMGQMNTLNSATLINKGLELIEATLLFETDADLIDVTVHPQSIIHSMITFTDGATIAQASPPSMKLPIALALDWPHRVPKAQPALDFTAAHTWTFEPVDDAAFPAVQLARHVAKQKGTYPAVYNAANEEAAEAFLRGRIKFPQIVDVVDEVLQGASQFAGVASHVDDILATESEARARANALINRLATNL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SAUS_CUPNH
Sequence: MSVQILHRRQSNNSDLPLPTASLPVQPAQAAAEAVAAVVARARQAQREFARADQATVDTAVAAAAWAIMEPARNRQLAERAVADTGLGNVDDKIRKNHRKTLGLLRDLHGRRTVGVIAQDAAAGITEIARPVGVVAAITPSTNPAATPANKIINALKCGNSVILAPSPKGQDTCALLLSFIHAEFARAGLPADLVQMLPAPVSKTATAELMRQADLVVATGSQANVRMAYTCGTPAFGVGAGNVASIIDASATLDDAAAKVARSKTFDNATSCSSENSLVVVDAVYTPMLDALAAVGGVLLTASEKARLQALMWRDAKLAGSFTGQSATRIAELAGLERVRALQPAMLLVEETGVGSDYPFSGEKLSPVLTLYRATDFAAAVERVASLYAYMGAGHSVSLHSSNPRHALQLGQELPVARVIVNQAHCFATGGNFDNGLPFSLSMGCGTWGGNNFSDNLGWRQYLNITRIAVPIAEHVPDEADLLGDYFARVGK
What is the function of this protein?
Catalyzes the conversion of sulfoacetyl-CoA and NADPH to sulfoacetaldehyde, CoA and NADP(+).  Specific for NADP(+) and sulfoacetaldehyde.
What are the official names of this protein?
Sulfoacetaldehyde dehydrogenase (acylating).
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y019_HIS1I
Sequence: MAKETNIEVLECPECSKELTIHIKTVVKPLLKKVQNTVWIKNE
What are the official names of this protein?
Uncharacterized protein ORF19.
Protein: PDC_ZYMMO
Sequence: MSYTVGTYLAERLVQIGLKHHFAVAGDYNLVLLDNLLLNKNMEQVYCCNELNCGFSAEGYARAKGAAAAVVTYSVGALSAFDAIGGAYAENLPVILISGAPNNNDHAAGHVLHHALGKTDYHYQLEMAKNITAAAEAIYTPEEAPAKIDHVIKTALREKKPVYLEIACNIASMPCAAPGPASALFNDEASDEASLNAAVEETLKFIANRDKVAVLVGSKLRAAGAEEAAVKFADALGGAVATMAAAKSFFPEENPHYIGTSWGEVSYPGVEKTMKEADAVIALAPVFNDYSTTGWTDIPDPKKLVLAEPRSVVVNGIRFPSVHLKDYLTRLAQKVSKKTGALDFFKSLNAGELKKAAPADPSAPLVNAEIARQVEALLTPNTTVIAETGDSWFNAQRMKLPNGARVEYEMQWGHIGWSVPAAFGYAVGAPERRNILMVGDGSFQLTAQEVAQMVRLKLPVIIFLINNYGYTIEVMIHDGPYNNIKNWDYAGLMEVFNGNGGYDSGAGKGLKAKTGGELAEAIKVALANTDGPTLIECFIGREDCTEELVKWGKRVAAANSRKPVNKLL
What are the official names of this protein?
Pyruvate decarboxylase, PDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: RS16_THISH
Sequence: MVTIRLARGGAKKAPFYHIVVTDSRSPRDSGYIEQLGYFNPVARGQEVRLHMNQERIEHWVSKGAQTSERVGKLLADFRKQNQA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS3_SYNP6
Sequence: MGQKINPVGFRLGVTQEHRSRWFADPNRYPQLLQEDKKIRDYVRKNLSNAGIADIRVERKADQVELEIRTARPGVVVGRGGAGIDTLREGLQALLKDSSRQIRINVIEVERVDADAALLGEYIAQQLERRVAFRRCVRQAIQRAQRAGVQGIKIQVAGRLNGAEIARTEWTREGRVPLHTLRADIDYAYTTATTTYGILGIKVWVFRGEIIPGQEDAAPSNVGQPRRRNQQRRRQQFEDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NCAP_I79A5
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGKKVVPRGKLSTRGVQIASNENVEAMDSSTLELRSRYWAIRTRSGGNTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFIGNNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: AIM2_YEAST
Sequence: MASNQPGKCCFEGVCHDGTPKGRREEIFGLDTYAAGSTSPKEKVIVILTDVYGNKFNNVLLTADKFASAGYMVFVPDILFGDAISSDKPIDRDAWFQRHSPEVTKKIVDGFMKLLKLEYDPKFIGVVGYCFGAKFAVQHISGDGGLANAAAIAHPSFVSIEEIEAIDSKKPILISAAEEDHIFPANLRHLTEEKLKDNHATYQLDLFSGVAHGFAARGDISIPAVKYAKEKVLLDQIYWFNHFSNV
What are the official names of this protein?
Protein AIM2, Altered inheritance rate of mitochondria protein 2.
What is the protein family that this protein belongs to?
Belongs to the AIM2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLG_PSEFL
Sequence: MEARVMTPFTYFSLPMQKQFLANQQAVQGKPYAEFFRSKISVPLSAVEKIQQGPMPLADTLTPSIEDLNRMLAADFISEEAGYALLPGPMAYVQSRKFFPNCTAEMLKWWFMWHPLEAERYTLWFPYAHVENPCVHHERLSDTTLSFEESLYGNTFCASEYVGDRLMHLHIHFRDPCELGFCPDLYRESKIDGSVSALMSLAHEPQVPVSLMAHLFKECPEGLYLTSRYWVGSHPAMQRFPGAERAAQLLEESGLGEVELETLAYEFAVHDMCEFNHLASILPSLHAQFSGAK
What is the function of this protein?
Hydrolase that specifically degrades the potent antimicrobial compound 2,4-diacetylphloroglucinol (DAPG) to equimolar amounts of mildly toxic monoacetylphloroglucinol (MAPG) and acetate.
What are the official names of this protein?
2,4-diacetylphloroglucinol hydrolase, DAPG hydrolase.
What is the protein family that this protein belongs to?
Belongs to the DAPG/phloretin hydrolase family.
Protein: TXLR3_EISFE
Sequence: MSATAVTADGLEEIEVDVVAVWKEGYVYENRGDTSVEQKITMTKGMKNLNSETKTLTATHTVGRTLKVGDPFEIGSVEVSYSFSHQESQVSMTQTEVYSSQVIEHTVTIPPTSKFTRWKLNADVGGTDIEYMYLIDEVTPISVTQTIPQVIRSRAKILVGRQIHLGTTAVRIKHAERQEYMTVIERKKWPAATLGKSNLFKFVLFEDSSGTRIKTLNTMYPGYEWAYSSDQGGVYFDESSDNPKQRWALSKALPLRHGDVVTFMNKYFTNSGLCYDDGPATNVYCLDKREDKWILEVVNP
What is the function of this protein?
Pore-forming toxin that specifically binds sphingomyelin in the plasma membrane of various cells.  Has antibacterial and hemolytic activity (By similarity).
What are the official names of this protein?
Lysenin-related protein 3, LRP-3, eflr3, efL3.
What is the protein family that this protein belongs to?
Belongs to the lysenin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a beta-barrel pore in the membrane.
Protein: DEF5_RAT
Sequence: MKKLVLLSALVLLALQVEAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRRKSCNWGEGIMGICKKRYGSPILCCR
What is the function of this protein?
Probably contributes to the antimicrobial barrier function of the small intestine.
What are the official names of this protein?
Defensin 5, Enteric defensin, RD-5.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAC_LEPVR
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CONA_CANCT
Sequence: ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVGKRLSAVVSYPNGDSATVSYDVDLDNVLPEWVRVGLSASTGLYKETNTILSWSFTSKLKSNSTHETNALHFMFNQFSKDQKDLILQGDATTGTDGNLELTRVSSNGSPQGNSVGRALFYAPVHIWESSAVVASFDATFTFLIKSPDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN
What is the function of this protein?
Glucose/D-mannose specific lectin.
What are the official names of this protein?
Concanavalin-A, Con A.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: PTJA_BACSU
Sequence: MNEEMEQIIFQIILHGGNGRSSAMEAIAAAKSGDAEEARKKLQDAAEELSKAHHYQTELIQNEAGGEKTEMTLLMVHAQDHLMNAMTVKDMAAEIIELYEKITEQRGASI
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  This system is involved in lichenan transport.
What are the official names of this protein?
Lichenan-specific phosphotransferase enzyme IIA component, EIIA-Lic, EIII-Lic, PTS system lichenan-specific EIIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T23O_NOCSJ
Sequence: MSDNFVSFGEQGAQLTYGSYLRLPQLLEAQHLESDPPAHDELLFITIHQVYELWFKQLLHEVSAARDAMLGGEAGGRLWWAQHLLTRVHVIERVLVQQIDVLETMTPQEFLEFRQRLAPASGFQSVQFRELEFLSGAKDPAYLERFRGITPAEKARLDARLSEPTLWDAFLAMLRSFGFAADSDAEVSAALRTAAHDRTRYAVVWALSEGLLQHDELAANWRARHVVMVERMIGSKSGTGGSSGSSYLRSRLPVQYYPLLWGLRSEL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: CXCR4_PIG
Sequence: MDGFRIFTSDNYTEDDLGSGDYDSIKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVREGDGRYICDRFYPNDLWLVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGYQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation.  Involved in the AKT signaling cascade (By similarity).  Plays a role in regulation of cell migration, e. g.  during wound healing.  Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.  Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).  Involved in hematopoiesis and in cardiac ventricular septum formation.  Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.  Involved in cerebellar development.  In the CNS, could mediate hippocampal-neuron survival (By similarity).
What are the official names of this protein?
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction. Early endosome. Late endosome. Lysosome. Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC) (By similarity).
Protein: DNAK_BORAP
Sequence: MGKIIGIDLGTTNSCVAIMEHGKPVVIQNSEGGRTTPSIVAYTNKGERLVGQVAKNQMVTNPENTIYSIKRFMGRRFEEVASEIKMVPYKIEKGLNGDARVNISNIKKQMSPPEISAATLTKMKETAEAYLGEKVTEAVITVPAYFNDAQRQATKDAGKIAGLEVKRIVNEPTAAALAYGIEKKHEEIVAVYDLGGGTFDISILELGDGVFEVKSTNGDTHLGGDNFDDEIIKHLISEFKKESAIDLSNDKMALQRLKEAAEKAKIELSGAQEASINLPFITADANGPKHLQYTLTRAKFEQMVDHLVQKTKEPCLKAIKDAGLKASDINEVILVGGSTRIPAIQKIVKDIFGQDPNKGVNPDEAVAIGAAIQGGILTGETKDMVLLDVTPLSLGIETLGGVMTKLIERNTTIPTKKSQVFSTAADNQTSVDIKVLQGEREMAAQNRILGNFILDGIPAAPRGVPQIEVSFDIDANGIVHVSAKDMGTGKEQKIRIESSSGLSESEIDRMVKDAEAHAEEDKKLKENIEAKNTANSLIYQTEKSLKEYSEKISIEDKETIENKIKELKESLEKEDISLIKSKTEELQKASYKIAEMMYKDSSQQNASNQQENGTQNNTSEEGKEADYEVVDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ADF10_ARATH
Sequence: MANSASGMHVSDECKLKFLELKAKRNYRFIVFKIDEKAQQVMIDKLGNPEETYEDFTRSIPEDECRYAVYDYDFTTPENCQKSKIFFIAWSPDTSRVRSKMLYASSKDRFKRELDGIQVELQATDPSEMSLDIIKGRVNL
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers.
What are the official names of this protein?
Actin-depolymerizing factor 10, ADF-10, AtADF10.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NHAA1_PSYIN
Sequence: MSSRGKWSWLHSPITGGILLIIAATTALFWANLAPSLYHHAWHDALFSVSSGFSATIYSISLHQIVNEFLMAIFFFFIGLEMKRELLDDDLSTLKKAALPLFSALGGVVLPASIYYFFNAGTDTVNGWGIPMATDIAFALGVLAMVGSRVPLSLKIFLSALAIGDDLMAVLVIAIFYTEQIFVNELLVGFLGLIVLAVANKMGVRNRLVYYSIGLIIVWISFLASGVHATIAGVAVAFTIPSRREISMGNYLITAKGLLSGLDKERHNKADVLTKNAISSLREIRDLSYQASNPLQLKEEALHPISALFIVPLFALGNAGVIVDDSMLAELTNPIVLGIAAGLIIGKPLGIFLFAKLLTLLKLGQLPEGVTWRHIIGTGFLAGMGFTMSLFISDLAFSEPEQKIVAKVAVLLASIISGIVGYLILISAPVIKKDNKLNS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PA2BD_CRODU
Sequence: HLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYRYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKYGYMFYPDSRCRGPSETC
What is the function of this protein?
Monomer CBd: The basic subunit of crotoxin is a snake venom phospholipase A2 (PLA2) that exhibits weak neurotoxicity (10-fold less than the heterodimer) and very strong anticoagulant effects by binding to factor Xa (F10) and inhibiting the prothrombinase activity (By similarity).  In addition, it shows the same effects described for the heterodimer and binds the nucleotide-binding domain (NBD1) of CFTR chloride channels and increases the channel current (By similarity).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:8513799).
What are the official names of this protein?
Phospholipase A2 crotoxin basic subunit CBd, CTX subunit CBd, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BAMI_PSEAE
Sequence: MAKTWIYAASAAAIGGALIGGWLLDPAPPEASPQARQSPAAQAAAAPTAALAAPAADATRMLAPTPVTTPAPRERVTLWQGELRSREGAQGIPEYLAQVEPALLDTLALGQVLEMSLPGRERPLQARLASTHNSAGLPVWRGGLVDGDEAESLTVVRGSLETHINVATLDGSYSIIVDNRSGKTRVIDENDIAARSDPHGDHVDAPLAELPPMPPPAQG
What is the function of this protein?
Inhibitor of the metalloendopeptidase Mep72.  Forms a protein-protein complex with the protease, which is the product of its coregulated adjacent gene, and probably prevents premature protease activity until the protein has been secreted.
What are the official names of this protein?
Biofilm-associated metzincin protease inhibitor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GGPS_SULAC
Sequence: MSYFDNYFNEIVNSVNDIIKSYISGDVPKLYEASYHLFTSGGKRLRPLILTISSDLFGGQRERAYYAGAAIEVLHTFTLVHDDIMDQDNIRRGLPTVHVKYGLPLAILAGDLLHAKAFQLLTQALRGLPSETIIKAFDIFTRSIIIISEGQAVDMEFEDRIDIKEQEYLDMISRKTAALFSASSSIGALIAGANDNDVRLMSDFGTNLGIAFQIVDDILGLTADEKELGKPVFSDIREGKKTILVIKTLELCKEDEKKIVLKALGNKSASKEELMSSADIIKKYSLDYAYNLAEKYYKNAIDSLNQVSSKSDIPGKALKYLAEFTIRRRK
What is the function of this protein?
Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylgeranyl diphosphate (GGPP) which is a precursor of the ether-linked lipids.  It is able to use dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and (all-E)-geranyl diphosphate (E-FPP) as an allylic substrate.
What are the official names of this protein?
Geranylgeranyl diphosphate synthase, GGPP synthase, GGPS.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: PTH_BAUCH
Sequence: MTIKLIVGLANPGNKYLLTRHNVGSWYVNQLANNYHVSLINKSSFLGYTGYLNIGKRRIFLLIPTIFMNYNGQAVAAIAKFYNIMPEEILIAHDELNFLPGYARFKYSGGHGGHNGLKDVIYRLGDNNNFYRLRIGIGHPGDKNKVIKFVLDTPLDTEQQLIQHAINESVLCTSLMFQQNIAYAIHQLHTILK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_LIMF3
Sequence: MAKKNHQGLDANLIAQNKKARHDYTVTDTFEAGLVLTGTEIKSVRARRVTLKDGYAQFHNGELWLMNVHIAEFAGGNIFNHDPLRNRKLLLHKKELKKLQGELTAKGVTLVPLKMYLKHGYAKVLLGLAQGKHEYDKRNAIKKREQDRQIDRVMKHY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: WUHO_DROAN
Sequence: MATIFFADPELVIGHGRRVLFVNPDDLQLFKEIELPPDLATCGLKVADSKEQHCQHEQQDVAAAGSAKQSSNTASASASKAKAIEVSIQNVSYSPDRQLLAITTTGGQKALLLYRSRMEHARLLSVRPLARASSALRFCSDGSSVLVTDKTGDCYQYDCVEVEAAPRLLLGHLSVVFDILWTDDQQHIITCDRDDKIRVTNYPATFDIHSYCLGHKEFVSGLALLTEQHIVSSSGDKTLRVWNFIEGKELLIHQLPAPAVRLQVQQLEPEKVYQVAVLFYDHVDGVAIYRLERSSGDNWAITATTVVRADAGLWNICNFTLTGNRVYVTGAENECLAIKAYDIGSGETSTSVPDGWVKMVLRGLEAEGVAYLPEDLSVWFKKRFDNVSDYLERKKRRIEEQQQQKCG
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: PFF1_LACBS
Sequence: MFLEINFYSTFFQRRPSLWKERCKFEEVDAQGNSISYSHHPPDLTGQRSPLTPTTMRIVDRIPTVVGFRVIPTTVLVLLTYLTIFTLVIVTDWLPEPPKNQNGLDLKQAYTDLRHITAHPHPYNSHYNDAVHDYILSRVRPVAASTSFVHISDDQTSNGSWASPGYGVYFEGTNILVKIDGKSSNGNDGVLFSAHYDSVSTAPGATDDGMGVVTLLQLIDYFAKHRPDRTAIFNINNGEEDWLNGAHAFLQHTWSNLTDTFLNLEGAAAGGRPILFRATSTSPVRAFRSDYVPHPHANVISSDAFARGVIRSGTDYEVYTGAGAEMEGLDVAFYKGRSRYHTKYDAVPYTNGGERSLWAMMETAQGAGNALLNAKRHKQDQGSGGTPVYFDLVKAELVIFYLNDLLIYNVVSLVVGPISLIFFVVCEYVLRNERARQPNGHPVSRPSVLEWLKQRSWLRALWRRSKFWIALVITIALQALLVWGYLAFNSFTVYSSPYLVLISFFSLAYLSLVIPLTFTFNQTQSPTAKYIAPEREKHTLLIQVYIFTWILLLFSTIAVARAQVGGLYFVTAWNTGVWIACLLAAVEGMMLPVPQGGPRVRFHSAHHHHHHEHEEDQDADDDDREQRQPPTEATPLIGYSRASLRKPQEGGVVGWWIVHLLLTIPAPVLLIAQMGSLLLDSLPQTLADGSPAYVVYAAASLTAVLLAVPLTPFSGKLHRGLFFLFFLSFLIVTAYLWLAFPFSSADPLKVFFQQKVTLSNVVSERHSSIMGLSNSTVHPTAGVRKVVTAITGTPYYLKNEIIPRLPSASGKELKCRDEKAKRGLVTCEWESTLVPSPGGRNPWEDDFAAAQGRVGATSKSRQSWFKAEVARTGVRKGQIVLQGRNTRSCRLYFDSRPIIKYVVEGGHEGMQKGYEVGKVGASEVRLWSRTRDREFVVDFEWEDDDGREGEGITGRIACEWVEYESGNLDNGDGQWDLQRGGGERAKIPAFEEVLAFLPEWAVASKTTDGLVEAWSPFSV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: HIS4_STAA9
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQYAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.