PharMolix/UniProtQA huggingface dataset:
Protein: MCFX_DICDI
Sequence: MVQQQQQQQQIKKNQVKPPLYSNLIAGAIAGVIGSSVVFPLDFVKTRLQQQRVSIDGSKQYNGIIDCFKKVIKNEGGVRGLYRGLSSNLIGIIPEKALKLAMNDYFRTRFQGDRSYIKLWEEVASGGLAGMCQVVATNPMELVKIRMQVSGLSGKKASLKEVVSELGIKGLYKGTASTLLRDVPFSMIYFSIYGRMKHNLTDQETGEIGLPKILLCGITAGSIAASVSTPFDVIKTRIQVKPGPNDPHYKGIADCFRKTIQSEGPKALFKGVLPRVCIISPLFGITLVVYEIQKSFYASTH
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial substrate carrier family protein X.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNAJ_HALLT
Sequence: MSDNFYDVLGVSRDASEEEIKKAYRKQAAEHHPDVSDDDDAEERFKAIQKAKEVLTDEQKRQQYDQLGHDRFTEADKRGATGGGGPGGAGGPFGGAGGAGGAGGFEDIFNQFFGGGGGRGGGGGNRPRQGQDLRTGLTIDLEEAFEGATKEVTLTRPTQCDTCDGAGHPPDADVETCSQCNGRGQVQQVQQTPLGRVQQTSTCPRCEGSGELYSEDCADCGGDGVVREEATLSVEIPAGIRSGQSLRMEREGAPGENGGPNGDLLIEVDVDVGDRFERDGDDLRVNEAVSFPQAVFGDTIEVETVDGSVEMDVPTGTQSGETFRLKGKGMPRLRRRGRGDLYVKVGVVIPDSLNEEQREALEAFAEAGGEDVDVGGGFFKKLKSSF
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LICR_BACSU
Sequence: MLHGRLRDILRLLMAAEAPVTSSFFAAQLNVTTRTVRNDIKELQGVLSGHGAFVQSVRGSGYKLRIDDEQVFRTLLQDEFQQKKGLPVLPEERMAYLMKRLLLADHYLKLDELAEELFISKSTLQTDLKEVKKRLLPYRIVMETRPNYGFKLRGDEVQMRYCMAEYIVDERETEIDVLNEKADILPKEEIEIIRSAILKKMKNDRIPLSNMGLNNLIIHIAIACKRIRTENYVSLFPKDMDHILHQKEYQAAEAIVKELESKLSVTFPKDETAYITMHLLGTKRMTQSQCGEDTFSIEEETDQLTLAMIKAVDRELKLGILHDKELKIGLALHMKPAISRNRYGMNLRNPMLAAIKEHYPLAFEAGIIAGIVIKEQTGIEIHENEIGYLALHFGAAIERKKTESPPKRCIIVCASGAGSAQLLREKLRSHFGKRLDILGTAEYYSLDQMSYESIDFVISTIPIKKELPVPVLKVNTILGGTDFTKIESILSDEKEKANRYLKKELVFFQEDLRSKEEVIQFLGQKVVECGFADEEIIDSIFEREDMSPTCFGNLVAIPHPLVPQTKTTFWAVCTLKKPIDWESQRVQFVCLLCVEKENKADLQSMYKLLGSILDDPAAMNQLIKCRSYQELSDVFDQKMLS
What is the function of this protein?
Positive regulator of the licABCH operon.
What are the official names of this protein?
Probable licABCH operon regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family.
Protein: GATC_NATTJ
Sequence: MKVSKEEVLHVAKLGQLDLDQEEVEMFQDKLSQILEWQEKLDELDLEGLEPTAHALERRNVTREDQVHNSLTNDKALENAPETEGNYFKVPRIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ACPS_METS4
Sequence: MIVGIGSDLCDIRRIERSLERFGERFTQRVFTPGERARSDRRAARAPSYARRFAAKEACAKALGTGLSQGVFWRDMEVVNLPSGAPTLRLTGGAAARLAALVPPGHRARLHVSLTDDPPLAQAFVVIEALRDESC
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLN_BURPS
Sequence: MTNQNRRDFLRLAAGTAGAAALQLFPPVIREALAIPANRRTGTIRDVEHIVILMQENRSFDHYFGKLRGVRGFGDPRPLALQNGKSVFHQPVLLGPAELLPFHPDASNLGMQFLQDLPHGWQDMHGAWNKGRYDRWIANKGTTTMAYLERDDIPFHYQLADAFTICDAYHCSIPSSTDPNRYYMWTGYVGNDGAGGGPVLGNEEAGYGWSTYPETLEQAGVSWKIYQDIGTGLDAAGSWGWTQNPYIGNYGDNSLLYFNQYRNAQPGSPLYDKARTGTNVSAGGTLFDVLQQDVKNGTLPQVSWICAPEAYSEHPNWPANYGAWYVEQVLKALTSNPDVWSKTALFITYDENDGFFDHVAPPFAPQSRENGLSTVSTAGEIFAGDATHMAGPYGLGPRVPMLVVSPWTKGGWVCSQTFDHTSLLQFIEARFNDRYSVRAPNVTPWRRAVCGDLTSAFNFSSPDGSWPQLPDTSGYAPPDRNRHPSYVPVPPAAQSMPKQEAGLRAARALPYELFVLGRIDQSTGKFKLTFANTGRAGAAFQVTAGNRLDGPWAYTVEARKRLSDEWSTALTLSIYDLTVYGPNGFLCQFRGSTAAALGLSANPEVIYGYDVANGNITLRLSNRGRAAVRLTVTNAYGNAAPRVYELKPGQRINDYWDLRDSHSWYDLSVSDGAPNGFLRRFAGHVETGRPSTSDPLIATA
What is the function of this protein?
Hydrolyzes phosphatidylserine as well as phosphatidylcholine.
What are the official names of this protein?
Non-hemolytic phospholipase C, PLC-N, Phosphatidylcholine cholinephosphohydrolase, Phosphatidylcholine-hydrolyzing phospholipase C, PC-PLC.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
Protein: SMC3_YEAST
Sequence: MYIKRVIIKGFKTYRNETIIDNFSPHQNVIIGSNGSGKSNFFAAIRFVLSDDYSNLKREERQGLIHQGSGGSVMSASVEIVFHDPDHSMILPSGVLSRGDDEVTIRRTVGLKKDDYQLNDRNVTKGDIVRMLETAGFSMNNPYNIVPQGKIVALTNAKDKERLQLLEDVVGAKSFEVKLKASLKKMEETEQKKIQINKEMGELNSKLSEMEQERKELEKYNELERNRKIYQFTLYDRELNEVINQMERLDGDYNNTVYSSEQYIQELDKREDMIDQVSKKLSSIEASLKIKNATDLQQAKLRESEISQKLTNVNVKIKDVQQQIESNEEQRNLDSATLKEIKSIIEQRKQKLSKILPRYQELTKEEAMYKLQLASLQQKQRDLILKKGEYARFKSKDERDTWIHSEIEELKSSIQNLNELESQLQMDRTSLRKQYSAIDEEIEELIDSINGPDTKGQLEDFDSELIHLKQKLSESLDTRKELWRKEQKLQTVLETLLSDVNQNQRNVNETMSRSLANGIINVKEITEKLKISPESVFGTLGELIKVNDKYKTCAEVIGGNSLFHIVVDTEETATLIMNELYRMKGGRVTFIPLNRLSLDSDVKFPSNTTTQIQFTPLIKKIKYEPRFEKAVKHVFGKTIVVKDLGQGLKLAKKHKLNAITLDGDRADKRGVLTGGYLDQHKRTRLESLKNLNESRSQHKKILEELDFVRNELNDIDTKIDQVNGNIRKVSNDRESVLTNIEVYRTSLNTKKNEKLILEESLNAIILKLEKLNTNRTFAQEKLNTFENDLLQEFDSELSKEEKERLESLTKEISAAHNKLNITSDALEGITTTIDSLNAELESKLIPQENDLESKMSEVGDAFIFGLQDELKELQLEKESVEKQHENAVLELGTVQREIESLIAEETNNKKLLEKANNQQRLLLKKLDNFQKSVEKTMIKKTTLVTRREELQQRIREIGLLPEDALVNDFSDITSDQLLQRLNDMNTEISGLKNVNKRAFENFKKFNERRKDLAERASELDESKDSIQDLIVKLKQQKVNAVDSTFQKVSENFEAVFERLVPRGTAKLIIHRKNDNANDHDESIDVDMDAESNESQNGKDSEIMYTGVSISVSFNSKQNEQLHVEQLSGGQKTVCAIALILAIQMVDPASFYLFDEIDAALDKQYRTAVATLLKELSKNAQFICTTFRTDMLQVADKFFRVKYENKISTVIEVNREEAIGFIRGSNKFAEV
What is the function of this protein?
Involved in chromosome cohesion during cell cycle and in DNA repair.  Central component of cohesin complex.  The cohesin complex is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
What are the official names of this protein?
Structural maintenance of chromosomes protein 3, DA-box protein SMC3.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. At anaphase, the MCD1 subunit of the cohesin complex is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Protein: GREA_BRUA4
Sequence: MEKFPMTPGGFEKLKEELRWRQQSERPRIIEAIAEARAHGDLSENAEYHAAKEAQSLNEGRINELEDLVARAEIIDVSKLSGDRIKFGATVTMIDEDTDEEKVYQIVGDQEADVKEGRISISSPIARALIGKGEGDTIEVNAPGGSRSYEIVGLKFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CDCA3_HUMAN
Sequence: MGSAKSVPVTPARPPPHNKHLARVADPRSPSAGILRTPIQVESSPQPGLPAGEQLEGLKHAQDSDPRSPTLGIARTPMKTSSGDPPSPLVKQLSEVFETEDSKSNLPPEPVLPPEAPLSSELDLPLGTQLSVEEQMPPWNQTEFPSKQVFSKEEARQPTETPVASQSSDKPSRDPETPRSSGSMRNRWKPNSSKVLGRSPLTILQDDNSPGTLTLRQGKRPSPLSENVSELKEGAILGTGRLLKTGGRAWEQGQDHDKENQHFPLVES
What is the function of this protein?
F-box-like protein which is required for entry into mitosis.  Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).
What are the official names of this protein?
Cell division cycle-associated protein 3, Gene-rich cluster protein C8, Trigger of mitotic entry protein 1, TOME-1.
Protein: PNP_BART1
Sequence: MFKTHKIEIEWAGRPLTLETGKIARQADGAVIATYGETIVLATVVSAKSPKPDQDFFPLTVNYQEKSYAVGRIPGGYLKRESRPSENETLVSRLIDRPIRPLFVEGYKNDTQVIVSVIQHDLENNPDILAMIASSAALTLSGVPFMGPIAGARVGYCNGQYVLNPHMDEMPESKLDLVVAGTESAVLMVESEAQELPEDIMLGAVMFGHKGLQPVLDAIIKLAEVAAKDPRDFVPEDLSDLEKAMQEMAEQDIRKAYTITDKQERYAAIDALKTEIINKFMPETEEDCQFSTDQIATVFKQLQAKIVRGNILDTKKRIDGRNLSTVRPIQSEVSILPRTHGSALFTRGETQAIVVATLGTGEDEQYIDALTGMYKETFLLHYNFPPFSVGETGRLGSPGRREIGHGKLAWRAIHPMLPTKESFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPLARPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTENGITALQMDIKIDGITEEIMKIALEQAKDGRIHILNEMAKALTSARAELSEFSPRIEVINIAVDKIRDVIGSGGKVIREIVEQTGAKINIEDDGTIKIASADAKTIEAAKRWIHSIVDEPEVGAIYQGTVVKTADFGAFINFFGSRDGLVHISQLASERVTKTTDIVKEGDKVWVKLMGFDERGKVRLSMKAVDQKTGKEMTDDKSVKEEKCMDEKKQPENKRRRKKKEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1_PAPSO
Sequence: MATMSSAAVEVISKETIKPRNPTPYQLRNYNMSLLDQYSSLVYVPIILFYPAASDANSTGSKHHDDLHLLKRSLSETLVHFYPMAGRMKDNMTVDCNDEGIDFFEVRIKGRMCDFMMKSDAHLSLLLPSEVASTNFVKEAQVIVQVNMFDCGGTAICFCISNKIADACTMITFIRSLAGTTNIARRGSSIAAPTTNQNLVPSFDSTSLFPPSEQLASQVSYPTQDSTSVDKLVSKRFVFDAAKITSAREKLQSLMHDKYKCHRPTRVEVVSALIWKSAVKSAPPGSISTVTHAMNFRKKMDPPLQDASFGNLCVVVTAVLPATTATTTNPATKKVSSTSNEEQVALDELSDFVALLRREIDKVKGDKGCMEKIIQKFIYGHDASVAKDSDVEDKVTALFMTSWCKFGFYEADFGWGTPVWVTTVPLIEPKYKNMVFMNDMKCGEGIEVWVNFLEDDMTKFEHHLREILQLF
What is the function of this protein?
Acetyltransferase involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:25485687, PubMed:27378283, PubMed:29610307).  Converts (13S,14R)-1,13-dihydroxy-N-methylcanadine to (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine (PubMed:25485687, PubMed:27378283).
What are the official names of this protein?
(13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase AT1, Acetyltransferase 1, PsAT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: ECTB_MARHA
Sequence: MMQNDLSVFNEYESEVRSYVRGFPTVFHQAKGYKLWDLDGKEYVDFFSGAGALNYGHNDENMKQKLLTYIQEDGVTHSLDMATKAKGEFIDAFQNIILKPRNMDYKIMFPGPTGANSVESALKLARKVTGRTNVVSFTNGFHGMTIGALSVTGNKFKRNGAGMPLSNTSTLPYDQFLKESNNSIEYIENFLDNGGSGLDKPAAFIVETVQGEGGLNAASSEWLRSIEKICRERDIKLILDDVQAGVGRTGTFFSFEPAGIKPDFVCLSKSIGGNGSPLAITLVAPEYDKFAPGEHNGTFRGNNFAFVTGTEALNYWKDDRLEKNVQEKSERITSFLDDMIKKHPEMKGVRKGRGFMQGIMSPIEDLADNIAGRCFEHGLIMETAGAEDEVFKLFPPITIDDEGLERGLSILQQAIEEVTAESNLVAK
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: MSP49_CAEEL
Sequence: MAQSVPPGDIQTQPGTKIVFNAPYDDKHTYHIKVINSSARRIGYGIKTINMKRLGVDPPCGVLDPKEAVLLAVSCDAFAFGQEDTNNDRITVEWTNTPDGAAKQFRREWFQGDGMVRRKNLPIEYNP
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein 49, MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: HIS1_CAUVC
Sequence: MSTPMIFAIPSKGRLKDQVEAWLADCGFKLEMTGGARGYSAELSGLPGVSVRLLSAGDIAAGLDSGDLHLGVTGEDLLRERGDDMDSRVMLLRALGFGRADLVVTAPKNWLDVDTMADVDEVGHAHLARTGRRLRVATKYVTQTRAFFARHGVADYRIVESSGATEGAPAAGAAELVVDITTTGATLAANGLKILSDGVILKSQAQLTASLTAGWNGEQLDALRRLLSVVEAKGRAGKLATLVWPAEQDRAAQDAVAAFIARGGSRRANGALLATADLFDAAAALAEAGVEPVTVSRPDYVFESRSAVLDRFAEALKSKI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_DESA1
Sequence: MAQVLVIVRVLPEDVETPLDELRKRIAGALPEGYELKMWDEEPIAFGLKALRLAIIMPEQTEGGTETLENLISQVQGVSQVEVEYVNRLS
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: MINC_LISMF
Sequence: MKKNVQIKGTKDGISIFLSDKASISELQQELTQLLADQKQNPYSGEKLEVQVQIGNRLFSEEEEREISTIIHENSQMKISAFYSNVMSKDEAKKWKENDQIFSMATIIRSGQVVQVPGDFLLIGDVNPGGQIRSNGNVFVLGNIKGIIHAGFEGNGNAIVAGKFLYPSQVRIADKVYGFDSEDYKEVTETDLFSAFVNDAGEIVIDGIHKIRKIRPEISNFQGGR
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: QUEC_AGRVS
Sequence: MKILVVCSGGLDSVSLADKMAAEHELIGLISFDYGQRHKKELDFAALAAKRLGVPHQIIDMTNIGASLTGSALTDDLDVPDGHYAEETMKITVVPNRNAIMLAIAFGVAAAKKADAVALAVHGGDHFIYPDCRPGFIDAFQIMQAHALEGYADVKLLAPFVTVSKADIVTEGAKYGTPFDQTWSCYKGGARHCGRCGTCVERREAFHLAGVTDPTDYEDPDFWVSATSGFQAREV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: IFNG_NUMME
Sequence: MTCQTYNLFVLSVIMIYYGHTASSLNLVQLQDDIDKLKADFNSSHSDVADGGPIFIEKLKNWTGSNEKKIILSQIVSMYLEMFENTDQSKPHIKHISEELCTLRDSLSDGVKKVKDLMDLAKLQMTDLRIQRKAANELFIVLQKLVDPPSLKRKRNQPQRRCNC
What is the function of this protein?
Produced by lymphocytes activated by specific antigens or mitogens.  IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions.  It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACSL5_MOUSE
Sequence: MLFIFNFLFSPLPTPALICLLTFGTAIFLWLINRPQPVLPLIDLDNQSVGIEGGARRGAFQKNNDLILYYFSDAKTLYENFQRGLAVSDNGPCLGYRKPNQPYKWISYKQVSDRAEYLGSCLLHKGYKSSQDQFVGIFAQNRPEWVISELACYTYSMVAVPLYDTLGTEAIIFVINRADIPVVICDTPQKATMLVENVEKGLTPGLKTIILMDPFDDDLMKRGEKCGVEMLSLHDAENIGKENFKKPVPPKPEDLSVICFTSGTTGDPKGAMLTHENVVSNMAAFLKFLEPIFQPTSDDVTISYLPLAHMFERLVQGILFSCGGKIGFFQGDIRLLPDDMKALKPTVFPTVPRLLNRVYDKVQNEAKTPLKKFLLNLAIISKFNEVKNGIIRRDSLWDKLVFSKIQGSLGGKVRLMITGAAPISTPVLTFFRAAMGCWVFEAYGQTECTGGCSITSPGDWTAGHVGTPVACNFVKLEDVADMNYFSVNNEGEICIKGNNVFKGYLKDPEKTQEVLDKDGWLHTGDIGRWLPNGTLKIVDRKKNIFKLAQGEYIAPEKIENVYSRSRPVLQVFVHGESLRSFLIGVVVPDPDSLPSFAAKIGVKGSFEELCKNQCVKEAILEDLQKIGKEGGLKSFEQVKSIFVHPEPFTIENGLLTPTLKAKRVELAKFFQTQIKSLYESIEE
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity).  ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity).  It was suggested that it may also stimulate fatty acid oxidation (By similarity).  At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL (By similarity).  May have a role in the survival of glioma cells (By similarity).  Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 5, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 5, LACS 5.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single- pass type III membrane protein. Cell membrane.
Protein: SYR_PYRHO
Sequence: MLMEIRESVKERIEEIIKEIAPQWEGEIELKETPDPKLGDFGTPIAFKLAKLLKRPPIEIAEKIVEKLKLNLPEGIKDVKAVNGYINVFIDYPHFARILINDILAKGDRFGSSEIGKGKKVIVEHTSVNPTKPLHMGHARNAILGDVMARILRFLGYEVEVQNYIDDLGIQFAQVYWGYLRLKEEFERIMNELRERGLKDNPIDHALGLLYVEVNRRLEDNPELENEIRDIMKKLESGELYGRKLAEEVVRAQMVTTYKLGVKYDLLVWESDIVRRKLFEIALELLSKNENFYIPSDGKYRGAFVMDLRKLFPDMKNPILVLRRSDGTATYTGKDIAYHLWKFGKIDVDLLYKEWDSTTWTTAPDGKSMPNKFGNANIVINVIGAEQKHPQLAIKYALQLLGFEDAAANLYHLAYEHVERPEGKFSGRKGTWVGFTVDEVIQEAVKRARELIEEKNPALSDEEKAEVAEKVGIGAIRYNLIKYSPDKKIIFRWEDVLNFEGESAPYIQYAHARCSSILRKAEEEGIKVDPETLFKNADFTKLSERERELVIMLSKFPRIVEQAGKDVKPHLIAWFANELASLFNKFYMDHPVLKAEEGVREARLLLVMAVEQVLKNALYLMGIEAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_ACET2
Sequence: MIKKPTSNVARLRKHKRVRKKVFGTPERPRLNVYRSLTNIYAQVIDDTVGRTLVSASSLEKEIKSKLGYCGNKQAAREVGKLVAQRALANGIKRVVFDRGGYIYHGRVKELAEGAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MBOA2_CHICK
Sequence: MATSTTGSTLLQPLSNAVRLPVDQVNFVVCQLFALLAAIWFRTYLHSSKTSPFIRHVVATLLGLYLALFCFGWYALHFVIQSGISYYLMIIIGVENMHKYCFVFALGYLTVCQITRVYIFDYGQYSADFSGPMMIITQKITSLAFEIHDGMFRKNEDLTPSQRCLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYQLQQSEANGKEDTKYEQTDPSPNIAVAQKLLICGLSLLFHMTITKTLPVEYNIDENFRATASWPVRVFYLYLSLMAARPKYYFAWTLADAINNAAGFGFRGYDKNGVTRWDLISNLRIQQIESSTSFKMFLDNWNIQTALWLKRVCYERATFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAIRNNIRHYFVESPAVKLCYDIITWMTTQVAISYTVVPFVLLSVKPSFTFYSSCYFCLHIASILVLLVFPLKRTQKGNKQHESIQPVWSKKLEEENLLQKNSYSTTNNSFSQKEEITCRYQALKQ
What is the function of this protein?
Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.  May catalyze preferentially the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) and lysophosphatidic acid (LPA) and to a lesser extend lysophosphatidylcholine (LPC) and lysophosphatidylserine (LPS).  Prefers oleoyl-CoA as the acyl donor.
What are the official names of this protein?
Lysophospholipid acyltransferase 2, LPLAT 2, 1-acylglycerophosphate O-acyltransferase, 1-acylglycerophosphocholine O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 2, O-acyltransferase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Endoplasmic reticulum.
Protein: RS16_EXISA
Sequence: MAVKIRLKRMGAKKSPFYRIVVADSRSPRDGRFIEQVGHYNPVAKPEAEVRINEELALKWLADGAKPSDTVRNLFSKAGIMEKFHNAKNAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: OBG_PSEMY
Sequence: MKFVDEVSIFVKAGDGGNGMMSFRREKFIEKGGPNGGDGGDGGSVFLEADENLNTLIDYRYTRKFHAQNGEKGGSTDCTGAKGEDLILPVPVGTTVIDVATQEVIGDLVKPGQRLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGESRDLKLELKVLADVGLLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPNLGVVSVDRFKSFVVADIPGLIEGASEGAGLGIRFLKHLARTRLLLHLVDMAPLDESDPAEAAQVIIDELGRFSPALAERDRWLVLNKMDQIPEDEREARKADIVARLGWQGPVYVVSAISRDGTERICRDIMHYLEVRAERIAEDPVFAEELAELDQRIEDEARARLQALDDQRALRKSGVRSVDDIDEDDDFFDDEDDDGPEIIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_NITOC
Sequence: MSATLDAPSPSKPRIVLGFDFGLRYIGVAVGQEVTHSANPLTTLKAHEGNPDWNQITQLIRQWNPDLLIVGLPLNMDQSEQFLTKAARRFGHRLHGRYGLAVEWVDERLSTVEARERLNIKSSASGRRQGIDQMAAQCILQTWLTEQQTIRH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.