PharMolix/UniProtQA huggingface dataset:
Protein: ASTD_SHEPW
Sequence: MTQFIEGKWTAGLGHEVTSINPANQEVIWNSKTATPEQVNTAVDAARNAQFDWFMLGFEARLAIVEAYRDQLEANKAEMAEVIAQETGKPQWETATEAGAMIGKIGLSVAAFHKRTGTSENDTPAGRAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPKVAELMLKLWEKAGLPAGVINLVQGEVETGKALASHPQIDGLFFTGSSRTGHILHQQYAGDPGKILALEMGGNNPLIIKGVEDTKAAVHDIIQSAYISSGQRCTCARRLYVEKGAAGDALLEQLAVAVNNIQVGAWNAQPQPFMGSMISETAAKGMVEAQRNLVNLGATPMVELTHLEAGTGLVSPGLIDVTDVIELPDEEYFGPLLQVVRYSDFDEAIKLANATRYGLSAGILADSREDYDYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADAVSLPAKLSPGLSI
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: REX_HTL3P
Sequence: MPKTRKQRSRRPRNQRPSTPWPISQVSDRAFSTGTLSTFSATVYRPIGAPFLGGFVPLGYTAMPCWPRAPNIRLPGTPSMDALSAQLYNTLSLGSPPSPPKELPAPSRFSPPQPLLRPPRFLHPSSTPLKNTPPSETIASSSPWESSCQPCPSPTLGSGPKTSTPYGAAPSCVSTSISSPPP
What is the function of this protein?
Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells.  These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR).  This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rex, Rev homolog, Rex-3.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Rex protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import (NLS) and nuclear export (NES) signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: MURD_AGRFC
Sequence: MIPVTSFRGKKVALFGLGGSGLVTARALVAGGAAVVAFDDNPDSVAKAQAEGIATADLHTIDWSSFSSFVLAPGVPLTHPKPHWSVDLAKAAGVEVIGDIELFIRERRVHAPDCPFIAITGTNGKSTTTALIAHILQSSGRDTQLGGNIGTAVLSLDPPKAQRFYVVECSSYQIDLAPTINPTAGILLNLTPDHLDRHGTMQHYADVKERLVAGSGTAIVGVDDSHSTLIADRIERAGVKVERISKRNVVSEGLYAEGSQILRAHGGTSSLLVDLDGIQTLRGSHNAQNAAAAIAACLAVGVSEEEIRAGLKSFPGLKHRMQPVGRRGNVTFVNDSKATNADAAAPALSSFDRIYWIAGGLPKAGGITSLSPLFPRIAKAYLIGEAAAEFAATLGEAVPYEISGTLDKAVQHAAADAEKDATAGNVVMLSPACASFDQYKNFEIRGDSFVAQVAALEGMTMLVHSGKGG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8E_METPE
Sequence: MLWQGKSIRKVTGGRYAPLRGKRRTEIGKAPAETHIGVDRKKMVRTFGGNVKVRALRATFASVANRSTGVCKQVKIETVEENSANPNYVRRNLLTKGAIIRTELGRARIMSRPGQDGVINAVLVE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: BSC1A_XENLA
Sequence: MAEGEDGSWWRSWLQQSYTSVRDKSAETLEFMKRDLTEFSRVVHHDTACTIAATASVVKEKLVVEGSSGTTEKVKKGLSDFLGVISDTFAPSPDKTIDCDVITLMATPSGTTELYDGTKARLYSLQSDPATYCNEPDGFPAEFDAWLAYWDPEQRKAEISELLVTSPSIRALFTKMVPAAVSHSEFWQRYFYKVHQLEQEEARRDALKQRADQSVHSEEPTWEEEEEDFVGAGSAPALKLEEKYVLSTPTIPTLHVEDKSEKTAELNRDHTSFTSPSESSESISPITQIANPEYIEQTPSKEPSPGTLTVTKENTGAGTDETSAPAPLEQKTGKSNTQMATQREDPPSDLRVFELNSDSGKSTPSNNGQKGSSTDISEDWEKEFDMTEEEVQLALSTVEVSGEVEDEDWENWE
What are the official names of this protein?
BSD domain-containing protein 1-A.
Protein: MTGA_XYLF2
Sequence: MYQWIQRDSDVHQRWIWCRRLLIVSLVSALMSVLQVIVFRFVDPPLSMTMVGRYLEAWSDRQWNFRLHYVWCDLEQIAPSVPISLVAAEDQRFPFHHGFDFDAIKKALGRHSRGGHLRGASTISQQVAKNLFLWSGRSFVRKGLEGWYTFWIELFWPKRRILEIYANIAEFGDGVYGVQAAARRYLGKGAADLDESDAAQLAAVLPSPRHYNIQHPGPYIRWRSSWIQRQAKQLGGSAYLDMH
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YD211_YEAST
Sequence: MLLNVTSSQYISTPQSRSLSEIDTSETASLSSATDHIFALSTEVVSSITTNLIEGLESSIQVPISTAYGTTSFRNNTSSPQYLVSNCTSSVQSNITIDRGLLSTLKTFTTSQVPTIEPSTTKLTTPLSTTFTSTSTSEIYSVFTSENSVYIIYDQEYKFTERSTTFNTHFPQTTVLQESNPPLTFTIPSNTITGDAKLYQYLSGALNTQDTSDANNRRTGVIVGSTVGVVIGVVIVIFIGFIIIRNRRNVKNHSKKGFSHDIGKRVSCDEVTETEAPSNPFLNVLNYKVTTNGEGKRDSFENGRDLHRASSSDGIYIAHPYYGMADHESGRFSYVSSYNESAESSIEETSSSASTITRPNIQQTNSFLREII
What are the official names of this protein?
Uncharacterized protein YDL211C.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: RL2_LEGPH
Sequence: MALLKSKPTSPGKRGEIRVVHHDIYKGKPHAALVEKLKKTGGRNNQGRITVRHIGGGQRQKYRIIDFKRNKDGILGRVERLEYDPNRTALIALISYKDGEKRYIIAPSNLEVGATIQSGADSPISVGNCLPLKNIPVGTTIHCVEMKPGKGAQMLRSAGCSGQLVAKEGVYATLRLRSGEMRKIHVLCRAVIGEVSNSEHNLRALGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGLPTKGYKTRSNKRTDTFIVRGRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PYRF_YARLI
Sequence: MPSYEARANVHKSAFAARVLKLVAAKKTNLCASLDVTTTKELIELADKVGPYVCMIKTHIDIIDDFTYAGTVLPLKELALKHGFFLFEDRKFADIGNTVKHQYKNGVYRIAEWSDITNAHGVPGTGIIAGLRAGAEETVSEQKKEDVSDYENSQYKEFLVPSPNEKLARGLLMLAELSCKGSLATGEYSKQTIELARSDPEFVVGFIAQNRPKGDSEDWLILTPGVGLDDKGDALGQQYRTVEDVMSTGTDIIIVGRGLYGQNRDPIEEAKRYQKAGWEAYQKINC
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: ATPD_PROMM
Sequence: MPLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKKAALQKLFANQVTPSFLNLLKLLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELSEQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGSKVIDASVAGQVRRLGLALAKVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: GCSP_ECOLC
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESCNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PSAA_SOLLC
Sequence: MIIRSPEPEVKILVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQLWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYADFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWACIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGATAPGATASTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGSVSDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PR1G2_ARATH
Sequence: MTPSPPPITYISIPLPTNDVVSRSIHNLTTAISSHRPWSELIFSGDFSLPESFSSLLLRSKTNFNYFFVNYTIIVSTCAAFALITASPVALIVVGAIIALWLIFHFFREDPLILWSFQVGDRTVLLFLVLASVWAIWFTNSAVNLAVGVSVGLLLCIIHAVFRNSDELFLEEDDAINGGLIGSNLR
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein G2, AtPRA1.G2.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YDBH_ECOLI
Sequence: MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRIALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKLPQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGEKVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFAMPLVPDGLPVSGHATATLNLPQEPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLSGRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTGEAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKVTQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATWDVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPIVWVRDAQHPSFSGALSLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLRGNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAWMPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTEEEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAFSGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEISRSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQAWLEQNARLPGNDCPQGKECEEKQ
What are the official names of this protein?
Uncharacterized protein YdbH.
Protein: SYC_CLAMS
Sequence: MTLRLHDSRTQSLRDFVPLVDGRVGIYVCGPTVQSAPHIGHLRSALAYDQLRRWLAYRGLDVTLVRNVTDIDDKVIDNARRGQEAGGTEEWWALAYRVELEFSRAYAALGILPPSYEPRATASIGEMQAIIGRLVERGHAYPADDGSGDVYFDTASWPEYGELTRQRAADMEAAADADPRAKRDVRDFALWKGAKPGEPASASWPSPWGAGRPGWHIECSAMSTRYLGAEFDIHGGGLDLRFPHHENELAQSRAAGDPFARYWLHNGLVAVAGQKMSKSLGNSLFAADLLASARPVVVRYFLGSAHYRSTLEFHDGALAEAEAALDRIETFLDRSARRLAGTRFQAEPAATDGAPAAVPDEFAEAMDDDLSVPQALAVLHDAVRAGNAALDAGDLQEAASLRADVSAMVAVLGIDPLADEWRTASDQPARRALQALVEHRIAERQTAREARDFALADRIRQELAEAGITIEDSPGGSHWSIDGE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERD22_RAT
Sequence: MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA
What is the function of this protein?
Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (By similarity).  Binding is pH dependent, and is optimal at pH 5-5. 4 (By similarity).
What are the official names of this protein?
ER lumen protein-retaining receptor 2, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
Protein: YCIZ_ECOLC
Sequence: MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVAESTPDIPKAPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: NADE_LIGS1
Sequence: MRPLQERIINELKVKPEINAEEEIRRSVDFLKDYLKKHPFLKALVLGISGGQDSTLAGKLSQMAISELREETGDDAYQFIAVRLPYGDQADEQDAMDAIEFMQADKTVRVNIKQAADAMVQSIEENGLEISDFNKGNIKARERMIAQYGIAGAVSGAVVGTDHAAEAITGFYTKYGDGGADITPLWRLDKRQGRAMLELLNAPEHLYKKVPTADLEEDRPALPDEVALGVTYNDIDDYLEGKEVADNVAEKIENWFLKTEHKRHMPINVYDTFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: HYP3_AGABI
Sequence: MFARISTIITTLFFAMLAAATAVPRTDPPPATGSQCTAVGGDVNCCNSVQDASNPIVGLLAGLLGIVLGPIQGLVGLTCNPISVIGGGNSCSSQTVCCTGNNFSGGLLVIGCSPINIDL
What is the function of this protein?
Plays a role in the emergence of aerial hyphae and strands.
What are the official names of this protein?
Hydrophobin-3.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PNM8A_HUMAN
Sequence: MSKTMAMNLLEDWCRGMEVDIHRSLLVTGIPEDCGQAEIEETLNGVLSPLGPYRVLNKIFVREENVKAALIEVGEGVNLSTIPREFPGRGGVWRVVCRDPTQDAEFLKNLNEFLDAEGRTWEDVVRLLQLNHPTLSQNQHQPPENWAEALGVLLGAVVQIIFCMDAEIRSREEARAQEAAEFEEMAAWALAAGRKVKKEPGLAAEVGSALKAETPNNWNATEDQHEPTKPLVRRAGAKSRSRRKKQKKNSRQEAVPWKKPKGINSNSTANLEDPEVGDAESMAISEPIKGSRKPCVNKEELALKKPMAKCAWKGPREPPQDARAEAESPGGASESDQDGGHESPPKKKAVAWVSAKNPAPMRKKKKVSLGPVSYVLVDSEDGRKKPVMPKKGPGSRREASDQKAPRGQQPAEATASTSRGPKAKPEGSPRRATNESRKV
What are the official names of this protein?
Paraneoplastic antigen-like protein 8A, PNMA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the PNMA family.
Protein: RS8_CYTH3
Sequence: MDPIADYLTKIRNAIKAKHRVVEVPASNIKKEITKVLFDKGYIQSYKFEESAVQGSIKIALKYHPLTKESAIVKIERISKPGLRKYTHAETMPRVLNGLGVAIVSTSKGIMSDKEAKNLNIGGEVLCFVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DCYD_SHIB3
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLNLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: AQP8_HUMAN
Sequence: MSGEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLLIRCFIGDGKTRLILKAR
What is the function of this protein?
Channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum membrane of several tissues (PubMed:26972385, PubMed:15948717, PubMed:18948439, PubMed:23541115, PubMed:29732408, PubMed:30579780).  The transport of the ammonia neutral form induces a parallel transport of proton, at alkaline pH when the concentration of ammonia is high (By similarity).  However, it is unclear whether the transport of proton takes place via the aquaporin or via an endogenous pathway (By similarity).  Also, may transport ammonia analogs such as formamide and methylamine, a transport favourited at basic pH due to the increase of unprotonated (neutral) form, which is expected to favor diffusion (PubMed:15948717).  Does not transport urea or glycerol (PubMed:15948717).  The water transport mechanism is mercury- and copper-sensitive and passive in response to osmotic driving forces (PubMed:15948717).  At the canicular plasma membrane, mediates the osmotic transport of water toward the bile canaliculus and facilitates the cAMP-induced bile canalicular water secretion, a process involved in bile formation (PubMed:18948439).  In addition, mediates the hydrogen peroxide release from hepatocyte mitochondria that modulates the SREBF2-mediated cholesterol synthesis and facilitates the mitochondrial ammonia uptake which is metabolized into urea, mainly under glucagon stimulation (PubMed:30579780, PubMed:34292591).  In B cells, transports the CYBB-generated hydrogen peroxide from the external leaflet of the plasma membrane to the cytosol to promote B cell activation and differentiation for signal amplification (By similarity).  In the small intestine and colon system, mediates water transport through mitochondria and apical membrane of epithelial cells (By similarity).  May play an important role in the adaptive response of proximal tubule cells to acidosis possibly by facilitating the mitochondrial ammonia transport (PubMed:22622463).
What are the official names of this protein?
Aquaporin-8, AQP-8.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RLMM_PSEMY
Sequence: MNTLFLHCRPGFEGEVCAEITDLAARLDVPGYSKAKPGSACAEFVCSEAADGERMMRSVRFNSLIFPRQWARGGFVMLPESDRISVLLDALADYPVCGSLWLEVVDTNDGKELSTFCKKFEAPLRKALLKAGKLVDDARKPRLLLTFKSGREVFAGIAEADNQAMWPMGIPRLKFPREAPSRSTLKLEEAWHHFIPREQWDQRLAPGMTAVDLGAAPGGWTWQLVNREIRVTAVDNGPMAESLMYSGFVVHQRADGFTFRPRHPVHWMVCDIVEKPARTAAMIETWLGEGLCREAVVNLKLPMKQRYAEVRRLLDRIESGLAERGLKVSIGCKQLYHDREEVTCHLRRHGK
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAB_LISMF
Sequence: MKHYVAVDIGASSGRLILGKLVDEKLQLEEIHRFKNGFTYRDGHERWEIDQLMQEIFIGLEKVKQLGISECVLGIDTWGVDYVLIGASGEKLADPISYRDKRTLNAVQNLTSEYPREYIYKKTGIQFMELNTLYQLYVEERDLLERAEKILLIPDYIGYVLTGVKVAETTNSSTTQMLNLREQLFDKDLLSHLNIDVEKFAPLTDAGTYLGKVKEEWLEKYDIPNCDVVTVATHDTASAVVGTPAEGENWAFLSSGTWSLIGMELSAPINNEAAFKENYTNEWGAYGTYRFLKNIMGLWIVQEIARMDDYKHSFAEMAEEASNYPYFKQIINVNDARFNNPENMVDEIKLYCQETGQTIPETIGELTNCVYGSLALYYALELEKMTEITGKKIEKLYIVGGGSNVAMLNQLTAKLAGIEVFAGPSEATAIGNLVVQMINQGEIESMRAGRKIIRNSFEIGEFSCGDVRFEEIKERFTKVLEFN
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: RS4_GEOKA
Sequence: MARYTGPMWKISRRLGISLSGTGKELQKRPYPPGQHGPGQRRKLSEYGLQLQEKQKLRHMYGVNERQFRKTFEEAGKMPGKHGENFMILLESRLDNLVYRLGLARTRRQARQLVTHGHILVDGSRVNIPSYRVKPGQTIAVREKSRNLQVIKEALEANNYIPDYLTFNPEKMEGTYTRLPERSELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KAD1_MOUSE
Sequence: MEEKLKKAKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRAEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLDSLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (By similarity).  Exhibits nucleoside diphosphate kinase activity, catalyzing the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and dTTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor (By similarity).  Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity).  May provide a mechanism to buffer the adenylate energy charge for sperm motility (PubMed:16790685).
What are the official names of this protein?
Adenylate kinase isoenzyme 1, AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase, Myokinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.