PharMolix/UniProtQA huggingface dataset:
Protein: GUAC_STRPQ
Sequence: MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEYEFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: LACB2_CAEEL
Sequence: MPSLTHVEPIEKLSDAVTRILGHNPGPFTLQGTNTYLLGTGAKKILVDTGEPNVTEYISALKSVLASTNSHIEYIVITHWHGDHVGGIDNITDEILDKKKIPIYKMKRDKDEGVERFHYVDDGFEVAVDGATLKLIATPGHTADHFSLWLQEERALFSGDCILGEGTTVFEDLHDYMTSLQKIKDLNATRIYPGHGPVIDKVVEKVDEYIEHRMKREREIIKVLKEHEEITSMDVTNQVYADSPWAVRLAALNNVKLVLKKLCKDGVVENPHFETFKWIGGSSSGEEKKNESSNL
What are the official names of this protein?
Beta-lactamase-like protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CYYR1_RAT
Sequence: MDALRLPRRLGVLLWKVVLLFVYAEDCRAQCGKDCRAYCCNGSTPHCCSYYAYIGSILSGTAIAGIVFGIVFIMGVIAGIAICICMCMKNNRGTRVGVIRAAHINAISYPMAPPPYTYDHETEYCTDLPPPYSPAPQASAQRSPPPPYPGNSRKYSSSQNRICNN
What are the official names of this protein?
Cysteine and tyrosine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the CYYR1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TPC13_XENLA
Sequence: MDVNQPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFSTLMKDDPSTVKGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDVQVKADLQTSSQRLNLSASSAVVADLKPDSCIDDVIHHEVKEIGTHILVCAVSYTIQSGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVSELNTVITNGDWKGSSTFGTKTYLQPLDTRQYLYCLKPKPEFAEKAGVIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSIETIPDTVRLEEPFDITCKITNCSSERTMDLVLEMCNTNAIHWSGVSGRQLGKLHPSSSLHLTLTLLSSVQGLQSVSGLRLTDTFLKRTYEYDDIAQVCVVSSKLQAES
What are the official names of this protein?
Trafficking protein particle complex subunit 13.
What is the protein family that this protein belongs to?
Belongs to the TRAPPC13 family.
Protein: TLP13_ORYSJ
Sequence: MSFRSIVRDVRDGFGSLSRRGFEVRILGHRRGKSHGAVHELHDPVPVIQSSCWASLPPELLRDIIERLEESEATWPSRKHVVACAGVCRTWREMCKEIVKNPELCGKITFPISLRQPGPRDGTMQCFIRRDKSTQTYYLYLSLGSAVLVDNGKFLLSAKRNWHATCTEYVISMNANNLSRSTNTNIGKLRSNFLGTKFVIYDTHTPYNATSDSQSGKTSRRFSNKGTAKHPCSTYSIANISYELNVFGTRGPRRMCCLMHSIPASSLEAGGTVPSQPDSILAHSLNESSFRSVSFSKSSVMDHSMHFSSAQFSDISIGDGPRIGGRVLSDDEECKETPLILQNKAPRWHEQLQCWCLNFRGRVTVASVKNFQLIAATQPAAGAPTPSQPVPPPPPEHDKVILQFGKVAKDMFTMDYHYPLSAFQAFAISLSSFDTKLACE
What are the official names of this protein?
Tubby-like F-box protein 13, OsTLP13, Tubby-like F-box protein 6, OsTLP6.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: NCCC_ALCXX
Sequence: MGAVLKAEANIFRSHPFRPMNQATPKKLRSAPCIGVALLLMATGSIQAAEAPPYSVLLQQSLAMAPTMMVQAANVRAAGADAAQARAWLNPRFDTLAENLGAPSSGGQSQRQNTYSITQPFEIGGKRGARIEVGERNYEAAQARERQLRVNYAAELAVAYATAEAAFGRQALAEENLALANEELTVARALVETGKEATLRTAQAQASVSAAQAIEAAASSDVTSTLARLSALSGATEAYTGISSSLLSAQPAMTPGGTTTDDSPAVRTAEAERNAFDAQVNVERKRWIPEVGITAGVRRYGWSNESGYIVGLTASIPLFDRNRNGIDAAVQRVAAAQARLDTVRLEANAARRSAVSQVAATDKQLAAASQGEQAASEAYRVGRLGYEAGKTPLVELLAVRRALVDARQLTIDARLARVRALAALAQADGRLAFEESR
What is the function of this protein?
Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium.
What are the official names of this protein?
Nickel-cobalt-cadmium resistance protein NccC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
Protein: RL28_HELPG
Sequence: MAKRCALTFKGPMVGNHVSHANNKNKRRLLPNLRSIKIQLDDGTTKRIKVAASTLRTMRKGA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: G1PDH_METKA
Sequence: MSVPKKRMQLPREVVVGSNVLPEVPKLLRSVGVPDGVVAVFSGRTTMKIAGNEVADHLEEAGYQTSPVIVKGSTGDDVKKALEALDEIDADVVAAVGGGKVIDVAKVASYRRGIPFISVPTSASHDGIASPFASIRREGRPYSEPAQAPLAILADIEVIREAPERLIRAGVGDVVSNVTAVKDWRLAHRLRNEPYSEYASSLSLMAARIVMKNAKPIGKLLPEGIKKLVQALISGGVAMSIAGSSRPCSGSEHLFSHALDVIAERPALHGEQCGVGTIIMEYLHGGNWREIRETLETAGAPTTAEDLGVSDEEIIEALCRAHKIRPDRYTILGDKGLTREAAERAAEETGVIQ
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6021_PARXL
Sequence: MKTFLLYAVTAVAEIVGCYLPWRWLKEGGSIWLLVPGALSLALFAWLLTLHGTAAGRVYAAYGGVYVAVAIAWLWCVDKVRPTLWDAAGVVFTLAGMAIIAFQPRV
What are the official names of this protein?
UPF0060 membrane protein Bxeno_B1021.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRC_LACLA
Sequence: MTLLIKNGRLVDPKSNRDEVLDILIENDKIVKIGLNLSVENAEIVDARGLVVAPGLIDVHVHFREPGQTHKETIHSGAKSAAAGGFTRVVMMANTKPILSTPKVLTETLEIADKEDIKIDAVGSITQDFDGEHLTDFDELIKAGAIGFSDDGIPLTDAGVLRKALQKAKLTDSLISIHEEDPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDSMIAYETGARLHIQHLSAGESVEVVRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRSTTDIGKIIEGLKDGTIDVIATDHAPHTREEKNVSLDKAPSGMIGLETSLQLGLTNLVAKGHLTLSELLTKMTVNPAKLYNFDAGYLAENGPADLVIFDAENDYQVGETFDSKATNSPFIKQKVQGQVKYTICDGKIVYQAK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: SIX2_MESMA
Sequence: DGYIKGKSGCRVACLIGNQGCLKDCRAYGASYGYCWTWGLACWCEGLPDNKTWKSESNTCG
What is the function of this protein?
On insects, this depressant beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active against insects and mammals.  It is capable of binding to not only cockroach neuronal membranes, but also rat cerebrocortical and hippocampal synaptosomes.  This toxin also has potent peripheral and central suppressive effects on rat nociceptive spontaneous responses, thermal hyperalgesia and spinal c-Fos expression induced by formalin and carrageenan, which may be derived from its modulation on the activity of sodium channels of the neurons.  Administration of BmKIT2 into rat brain can also suppress the epileptic seizures significantly.
What are the official names of this protein?
Beta-insect depressant toxin BmKIT2, Depressant insect toxin BmK IT2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CBP4_NEUCR
Sequence: MAAKKPVNWWLWTKMLLGGAAICVGGPAFTYWLTPTDEELFQKYNPELQKRSLERRFERQQEFDDFVTKLKEYSKSDKPIWTVQAEAEEKERQQRASVQKSLALADEVKARKEAMRREAGLPLEK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor cbp-4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PROF2_LILLO
Sequence: MSWQTYVDEHLMCEIDGQHLTAAAIIGHDGSIWAQSESFPQVKSEQITGVMNDFAEPGSLAPTGLFLGDNKYMVIQGEPGAVIRGKKGSGGVTIKKTNMALIVGIYDEPMTPGQCNMVVERLGDYLYDQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TAL_NEIMA
Sequence: MTILSDVKALGQQIWLDNLSRSLVQSGELAQMLKQGVCGVTSNPAIFQKAFAGDALYADEVAALKQQDLTPKQRYETMAVADVRAACGVCLAEHESTGGKTGFVSLEVSPELSKDAQGTVEEARRLYAAIGCKNAMIKVPATDAGIDALETLVSDGISVNLTLLFSRAQTLKAYAAYARGIAKRLAAGQSVAHIHVVASFFISRVDSALDTTLPDRLKGKIAIALAKAAYQDWEQYFTAPEFAALEAQGANRVQLLWASTGVKNPAYPDTLYVDSLIGAHTVNTVPDATLKAFIDHGTAKATLTEGADEAQAQLAEIAALGIDVETLAARLQEDGLKQFEEAFEKLLAPLV
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_SHEHH
Sequence: MKSHTQSLLAESLNALKQQGIVPADFEARIQVDRTKDKSHGDFATNLAMMLTKAAGKNPREIAQLLIDNLPESAHVEKVEIAGPGFINFFIDDNALANQLMVALNSDHLGLELPTPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFMGHKVIRQNHVGDWGTQFGMLLAYMEELRAANGEQAKMELSDLENFYRAAKVRFDESAEFATRARKLVVELQSGDEYCNKLWREFNDISLSHCHELYERLGVSLTRADVRGESAYNSDLAQVVADLDAQGLLSESNGAKVVFQDEFKNKEGEPLPVIIQKADGGYLYATSDLAAMRYRSNVLNADRALYFVDLRQALHFQQVFKLAKTAKFVREEMSFEHMGFGTMNGEDGRPFKTRSGGVVKLIDLLKEADTRALDLVRSKNPDMDEAELAEIARVVGIASVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRAQDVDLSDATIILEHEKEKDLGTKLAQFGEVMTRMVGKGQPHALCGYLFELAGAFSSFYEACPVLAAETEESKKSRLLLSQLTAKTLKQGLNLLGLETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTSL1_ARATH
Sequence: MGVGDPLPLPPEKNRREVNKPPDIASTSSSSASAVNNARLSDAPILLFVYFHKAFRAQLAELQFLAGDTVRSGSDLAVELRSKFEFLKLVYKYHSAAEDEVIFSALDTRVKNIVFNYSLEHDATDDLFTSVFHWLNVLEEEQGNRADVLREVVLCIGTIQSSICQHMLKEERQVFPLMIENFSFEEQASLVWQFICSVPVMVLEEIFPWMTSLLSPKEKSEVETCFKEVVPNELSLQLVINSWLIDDSQSSLTALTKIMKGVQSVEVSENMTNSQTNSSSSGVFQRFWQWSKKMSFSSPNTGHILVHGIHLWHNAIRKDLVDIQKGLCQLTFPSLSLDLNVLVVRLNFLADVLIFYSNAFKTFFYPVFEDMVDQQHSSSSKQFTIDGHVENFKKSLDLETRAGSDNFVITLQEKLESLILTVAKQFSIEETEVFPIISKNCNIEMQRQLLYRSIHFLPLGLLKCVIMWFSAQLPEDECQSIIHYLSSEDSFPNKPFAHLLLQWFRFGYSGKTPVESFWNELSFMFKPRCSFEEELTEEASGSFFQQSPQKLFKVSDPYSMDPPAGYMNETPYSSAMNQQILIPGKLRPLLHLPDLFGDKTIGEHLTMDLKPIDLIFYFHKAMKKDLDYLVRGSARLATDYSFLGEFQQRFHLIKFLYQIHSDAEDEIAFPALEAKGKLQNISQSYSIDHELEVEHLNKVSFLLNELAELNMLVLDHKNVKYEKLCMSLQDICKSIHKLLSEHLHREETELWCLFRDCFTIEEQEKIIACMLGRISGEILQDMIPWLMESLIPDEQHAVMSLWRQATRKTMFGEWLTEWYNSHAVEEETEEANKDPSENSDPLDVVWSYLFEGAADEYKGSICSKPLEETELKGIMNKPLGKAAPNNKVEFGNKEENHLEISGSKKVCTGADETKYKEQTDSNAQAFQMSHNTSQSGQDSRYECLLSMSQEDVEATIRRISRDSSLDPQKKSYIIQNLLMSRWIATQRIYNLEPSILSSNREAVPGQNPSYRDPHKLIFGCKHYKRSCKLLAPCCNKLYTCIRCHDEEVDHLLDRKQITKMMCMKCMIIQPVGASCSNISCSSSMGKYYCKICKLFDDDREIYHCPYCNLCRLGKGLSIDYFHCMKCNACMSRLIVEHVCREKCLEDNCPICHEYIFTSNSPVKALPCGHVMHSTCFQEYTCSHYTCPICSKSLGDMQVYFRMLDALLAEQKMPDEYLNQTQVILCNDCGRKGNAPYHWLYHKCSSCASYNTRLF
What is the function of this protein?
Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.
What are the official names of this protein?
Zinc finger protein BRUTUS-like At1g18910.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus.
Protein: CDPAS_METTH
Sequence: MNTDIINIIDVLYVIYFMLPAYMANISGLVFGGGKPLDMGITLADGRRLIGDGVTWRGTAAGTFVGLVVGIIQGLLSGSIIIGVITGLLLGFGALMGDAAGSFIKRRLKIDRGRPAPILDQLDFVFGALILVSPIVVLPIDYIILIMLITLVLHLSANIIAYLLGMKDVWY
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYS15_PLARH
Sequence: MFTVKLLAFMVVAVSLQHLAEATPKVCAGCPVEVDPNREDIKKSLAHVMAAKNSPDELVRIIKASTQVVNGIKYKVVFEVKNPSTNQVKICKTAYVSRPWEYEGYNVLEFGCKA
What are the official names of this protein?
Cystatin Pr15a, Venom cystatin domain peptide Pr15a.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_PROM3
Sequence: MAHPKAAEVRKLTDADITEQIDGIRRELFDLRFQQATRQLSNTHRFKESRTKLAQLLTVQKERSRSAAAS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RCNR_SALCH
Sequence: MSHTIRDKQKLKARTSKIQGQVIALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQSDEVRREEDLDVILKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR homolog.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAUG_PARDP
Sequence: MLRLACLAPLAILIPAAGTAEQARPADDALAALGAQLFVDPALSRNATQSCATCHDPARAFTDPREGKAGLAVSVGDDGQSHGDRNTPTLGYAALVPAFHRDANGKYKGGQFWDGRADDLKQQAGQPMLNPVEMAMPDRAAVAARLRDDPAYRTGFEALFGKGVLDDPERAFDAAAEALAAYQATGEFSPFDSKYDRVMRGEEKFTPLEEFGYTVFITWNCRLCHMQRKQGVAERETFTNFEYHNIGLPVNETAREASGLGADHVDHGLLARPGIEDPAQSGRFKVPSLRNVAVTGPYMHNGVFTDLRTAILFYNKYTSRRPEAKINPETGAPWGEPEVARNLSLAELQSGLMLDDGRVDALVAFLETLTDRRYEPLLEESRAAQKD
What is the function of this protein?
Involved in methylamine metabolism.  Essential for the maturation of the beta subunit of MADH, presumably via a step in the biosynthesis of tryptophan tryptophylquinone (TTQ), the cofactor of MADH.
What are the official names of this protein?
Methylamine utilization protein MauG.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS18_BARHE
Sequence: MTEMNQTAIRRPFHRRRKTCPFSGTNAPKIDYKDIKLLQRYISERGKIVPSRITAISQKKQRELANAIKRARFLGLLPYVIK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EIF3I_BRUMA
Sequence: MKPLSLKGHDRALTRVRINRDGDLLFSAGKDKSPCVWYMENGERIGTYDGHNGVIWDIDVSWDTRHFCSASGDVFVKLWNCETGDVINSVSTPTAARSISLSYSGNLIAFTTIKMTQNVASLFVYDIRDGSQMSGENQPTFRKSLQTQANSCVWTHLDDTVCVGNEKGNVHQYDIRKGDDIVNFNDEAHKFQINDMQMSTDESFLITASKDKTARLFDARTLDCLKTYKAERPVNSAAISPIRDHVILGGGEEAMKVTQTTAASGHFEAKLYHLVFEEEFARFKGHFGPINTLAFHPGGNCVVSGGEDGYVRIQEFDTDYLKFDYDF
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAZ1_DANRE
Sequence: MVKSNLQTILNSHCFVREKESNIPKMPVIELTRNKPESESSHRCSNPCPGPLWCSDVPLPPLKIPGGRGNDQRDHSLSAKLFYSDAQLLVLEEAPQSNSRVRFLLFERRCSVSKHLVWRGALKGTNLYIEIPTGVLPEGSKDSFSLLLEFAEEKLQVDHVFICFHKSRDDRASLLRTFSFMGFEIVRPGHPLVPTRPDAFFMAYRIERDSDGDE
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
What are the official names of this protein?
Ornithine decarboxylase antizyme 1, ODC antizyme, short form, ODC-Az-S.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: PCFT_DANRE
Sequence: MEDSDTSAILAEDSESVDSRTVCRCFRVTENKAPPPCSCPLSVTVEPVMFLSTFSIVLQAPLCTQYLWDRLSEDVGYNGTKTGGCNASTVHDPLQTEVETLTAHWSLYINLGGFLVGLFMVILLGSWSDRAGRRLVLIIPSLGLAVQAAVYLTVMYLKLPVFWFLIGRICSGLSGDFNAILAGCFAYVADTSERGSRTFRVAILEACLGLAGMFASIIGGQWRRAQGYINPFWLVLATNLTAALYAYLFVPETVTPDPQARLFSTRHHQAVCRLYSSDAPPGRRSKLWLYILCFFLVVTVHLGCSDLYVLYELSAPLCWGPELIGYGSAAKHLAYLTSLTGLRAMQCCLEDSWVALVGLTSNMVGLVVISVADTTALMFTGYGLCFLFMASTPVLRSKLSKLVDPAEQGALFASVACVEGLCSLVSSGVFNALYPATLHFMKGFPFVFGAAILLIPAGIIGGLGCQEKRESRENREGFGIS
What is the function of this protein?
Proton-coupled folate symporter that mediates folate absorption using an H(+) gradient as a driving force (By similarity).  Involved in the intestinal absorption of folates at the brush-border membrane of the proximal jejunum, and the transport from blood to cerebrospinal fluid across the choroid plexus (By similarity).  Functions at acidic pH via alternate outward- and inward-open conformation states (By similarity).  Protonation of residues in the outward open state primes the protein for transport (By similarity).  Binding of folate promotes breaking of salt bridge network and subsequent closure of the extracellular gate, leading to the inward-open state and release of protons and folate (By similarity).  Also able to transport antifolate drugs, such as methotrexate and pemetrexed (By similarity).  Also acts as a lower-affinity, pH-independent heme carrier protein and constitutes the main importer of heme in the intestine (By similarity).  Imports heme in the retina and retinal pigment epithelium, in neurons of the hippocampus, in hepatocytes and in the renal epithelial cells (By similarity).
What are the official names of this protein?
Proton-coupled folate transporter, Solute carrier family 46 member 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SLC46A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Cytoplasm. Note=Localizes to the apical membrane of intestinal cells in iron-deficient cells, while it resides in the cytoplasm in iron-replete cells (By similarity). Localizes to the basolateral membrane of choroid plexus (By similarity).
Protein: PYRI_METTH
Sequence: MDMKKPFELRVKPIKNGTVIDHITANRSLNVLNILGLPDGRSKVTVAMNMDSSQLGSKDIVKIENRELKPSEVDQIALIAPRATINIVRDYKIVEKAKVRLMDEVRGILRCPNPNCITNSDEGVENRFYVISEEPVLLRCYYCERLIEADEIESQF
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: Y2062_SULTO
Sequence: MIRLPAVAGAFYEGEEDKLKKQIEWSFLHPLGPGKIPQVPPQKSKRNNLFFIVPHAGYMYSGPVAAHAYYYLASEGIPDTVIILGPNHTGLGSYVSLWPKGKWKTPLGEIEIDEQIAMDLVRESEVIDIDEKAHLYEHSIEVQVPFLQYFFDSKTKIVPIVIMMQTPEISEYLAEGISKIMQKYKDKDIVVIASSDMNHYEPHEKTIEKDNMAIEKILSLDYKGLFNVVEEKDVTACGFGPMMTVLMLAKKFNKKPYVLKHATSGDTSGDKSSVVGYLSVRFGD
What are the official names of this protein?
MEMO1 family protein STK_20620.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: SCO1_BACSU
Sequence: MKVIKGLTAGLIFLFLCACGGQQIKDPLNYEVEPFTFQNQDGKNVSLESLKGEVWLADFIFTNCETICPPMTAHMTDLQKKLKAENIDVRIISFSVDPENDKPKQLKKFAANYPLSFDNWDFLTGYSQSEIEEFALKSFKAIVKKPEGEDQVIHQSSFYLVGPDGKVLKDYNGVENTPYDDIISDVKSASTLK
What is the function of this protein?
Necessary for insertion of copper into the active site of cytochrome c oxidase.  May play a role in copper homeostasis or redox signaling.
What are the official names of this protein?
SCO1 protein homolog, BsSco.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MIAB_RHOBA
Sequence: MISMTKTVYIKTVGCQMNVLDSEMVIADLKRHGYTVVDTPGEADLLLYNTCSIREQAEEKTYSALGKLKETKARHPEKTIGVMGCMAQKDQETIFRRAPFVDMVVGPGQLHAIPDMLTKVTSGEGRQMAVSLGRKDGKQTVVARSHETFDPLRDPTMRPTPFQAYLRIQIGCDKFCTYCVVPNTRGPEQGRSPEEIVSEARVLAEQGALEITLLGQTVNSYRHRGPDGETDMAGLLERLHDIDGLKRIKFVTNYPKDMTARLLETIRDLPKVSPYLHVPAQSGSDAVLKRMKRGYTIADYMEMFERIETVLPEASVSSDFIVGFCGETDEDFQKSVKLIERCRFKNSFIFQYSVREGTKAAANLIDDVPREVKAARNNELLAVQDRISKEDNQKLIGDTVEVLVEGPSKKADKSDLDAPIVQMTGRTICDRIVVFDGNRRQAGQLMDIQIDDVSSHTLIGRVKTVEVVSLGMPGLAPSS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFR_PEA
Sequence: MATENKILILGATGAIGRHIVWASIKAGNPTYALVRKTSDNVNKPKLTEAANPETKEELLKNYQASGVILLEGDINDHETLVNAIKQVDTVICAAGRLLIEDQVKVIKAIKEAGNVKRFFPSEFGLDVDRHDAVEPVRQVFEEKASIRRVVESEGVPYTYLCCHAFTGYFLRNLAQIDATDPPRDKVVILGDGNVRGAYVTEADVGTYTIRAANDPNTLNKAVHIRLPNNYLTANEVIALWEKKIGKTLEKTYVSEEQVLKDIQTSSFPHNYLLALYHSQQIKGDAVYEIDPAKDVEAYDAYPDVKYTTADEYLNQFV
What is the function of this protein?
Reduces achiral isoflavones to chiral isoflavanones during the biosynthesis of chiral pterocarpan phytoalexins.  The reduction product (sophrol) is a third isomer, which represents the penultimate intermediate in the synthesis of the phytoalexin (+)-pisatin, the major phytoalexin in pea.
What are the official names of this protein?
Isoflavone reductase, IFR, 2'-hydroxyisoflavone reductase, NADPH:isoflavone oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.