PharMolix/UniProtQA huggingface dataset:
Protein: IL2_AOTNI
Sequence: MYRMQLLSCIALSLALITNSAPTSSSTKKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNINVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIISTLT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHAT_ECO45
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSZ_SHIDS
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPRIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAPA_VIBVU
Sequence: MKMTRRAFVKANAAASAAAVAGITLPASAANLIASSDQTKITWDKAPCRFCGTGCSVLVGTQNGKVVATQGDPEAPVNKGLNCIKGYFLSKIMYGQDRLTQPLLRMKDGKYDKEGDFTPVSWDVAFDTMAEKWKASLAKKGPTSIGMFGSGQWTVMEGYAAAKMMKAGFRSNNIDPNARHCMASAVVGFMRTFGIDEPMGCYDDFEHADSFVLWGSNMAEMHPVLWTRITDRRLSHPHVKVNVLSTYYHRSFELADSGYIFKPQSDLAIANFIANYIIQNDAVNWDFVNKHTNFKQATTDIGYGLRDDDPLQKQAKNPNSGNMTSISFEEYKKSVAPYTVEKASEMSGVAQDKLIELAKQYADPNTKVMSLWTMGMNQHTRGVWMNSLVYNIHLLTGKISTPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVANPKHRAIAEKIWKLPEGTIPPKPGFHAVLQDRMLHDGVLNCYWVQCNNNMQAGPNINGERLPGYRNPENFIVVSDPYPTATAQAADLILPTAMWIEKEGAYGNAERRTQAWYQQVGTVGEAKSDLWQVMEFSKRFKMEEVWPEELLAKAPQYRGKTMYDMLFANGQVDKFPLSEARQLNDDSHHFGFYVQKGLFEEYAEFGRGHGHDLAPYDVYHTVRGLRWPVVDGKETLWRYKEGSDPYAKKGSGWDFYGKPDGKALIISAPYEAPPESPDAEYDMWLCTGRVLEHWHTGTMTRRVPELYKAVPDAVCYIHPEDAKARGLRRGDEVLISNKRGEVRVRVETRGRNRPPQGLVFVPFFDARILINKLILDATDPLSKQTDFKKCPVKITKVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y5360_PARP8
Sequence: MNSTSDDNPRPALRALTPLEARVLGVLFEKQHTVPDTYPLSLNSLAAGCNQKTSRSPVMNVSESEILDAINTLKRLSLVLEGSSSRVPRYEHNIERVLGLPRQSAALLTALLLRGPQTAAELRLATSRLHSFADTSSVEAFLEELAGNDPPRVVKLPRTPGERESRWMHLLCGEPSAEQLRGAALSDEPLPPGELEGLRAQQRELSERVERLEALVVHLAGELGVSLDDLKGRL
What are the official names of this protein?
UPF0502 protein Bphy_5360.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: GPI18_ASPFU
Sequence: MSRMTVLSPSAGSQSACSLGLILVNPRRPLRSLSILFGLWKALIFLVIVICPGLGYDTSTSLLLYPTRDLSDVDPLHFPLSLRFVRWDSIYFVHAAEHGYVFEQEWAFGYGYTRLLALLASVLVLYRLSVNIFGGDTAKQKTLCFLSAALHIISPAGAFLSAPYGEALFSLLNISGLYLYSSSVLDAATNHRLSRDLKLLAAAVLISAATAVRSNGILGGVLFAYDALLQLPQILSRGLSLAVVSRLAVIVLGGCVIALGMAVPQYIAFNAFCMTSNAPRPWCGWTIPSIYRFVQEKYWNVGFLRYWVVPNIPLFLLAMPILALLLRSAFWAWRLPSVTSKFSENGANGALTKAMWLLPRLAIIQALLAVLAFTSYHVQIINRLSSGYPLWYWYLAAELISDFKNSQSTNKCISISAVAVQAIMIYGLIHAVLFGSFLPPA
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 2, GPI mannosyltransferase II, GPI-MT-II, Glycosylphosphatidylinositol-anchor biosynthesis protein 18.
What is the protein family that this protein belongs to?
Belongs to the PIGV family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MRAY_XANCB
Sequence: MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLILLTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVRRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITFYIPMFKAIALPLAGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGELIIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTVAVIVRQELVLVIMGGVFVIETLSVMIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_OENOB
Sequence: MVQILDGRSVSKKILQEVKDKVAKAGFPVKLATIYNEENEGSKMYVGMKIRRATFAGLISVEYKVDNSWKTDDILRLLSKLNMDSSICGILVQSPLGDGIDESKIFNAIDPLKDADGLSAFNQGLLFENAKENYIVPATPAGVISLLEAYHYQFAAKNALVVGRSVLFGRPMSVLLTNRDMTVTLAHSKTPVDQLRQFAKRADLIVVAIGKANWFQFTDLKKDVVVIDVGANKLNGHATGDVDFEKVYPHVSQISPVPGGVGPMTIATLIKHTFDLAVFQQGEQK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: EX7L_BRUSU
Sequence: MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAASHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVLPGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSTD3_MOUSE
Sequence: MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQAFCSTPKGVTYRELKSLLNSKDIMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES
What are the official names of this protein?
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3, Rhodanese domain-containing protein 3.
Protein: RL22_TREDE
Sequence: MTERTGYRATTKFLIASPTKVRPVANVVKNKPYPEAMAILENMPQKGAVLISQTMKSAASNALYKNKQLDEDMLFVKEIMIDEGPRLKRIWCRGKGRADILLKRMCHITVVVDERAGE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: S19A3_MACFA
Sequence: MDCYRTSPSNSWIYTTVILCIFGFFSMMRPSEPFLIPYLSGPDKNLTSEEMTNEIFPVWTYSYLVLLLPVLVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTATEVAYYAYIYSVVSPEHYQRVSGYCRSVTLVAYTAGSVLAQLLVSLANLSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPDCEKQKPTSEIPSTSGKLHKGQLNSLKPRNVTVEVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQILNYVQILWDYKSPSQDSSIYNGAVEATATFGGAVAAFAVGYVKVNWDLLGELALAVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLSVERYALVFGINTFIALVIQTIITVIVVDQRGLNLPISIQFLVYGSYFAVIAGIFLMRSMYIIYSTKSQKDVQSPAPSENPDMSHPEEESNAIMSTKL
What is the function of this protein?
Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism.  Has no folate transport activity (By similarity).
What are the official names of this protein?
Thiamine transporter 2, ThTr-2, ThTr2, Solute carrier family 19 member 3.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 3S13_NAJMO
Sequence: LNCHNQMSAQPPTTTRCSRWETNCYKKRWRDHRGYKTERGCGCPTVKKGIQLHCCTSDNCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 3, NMM III, Neurotoxin III.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BCP1_USTMA
Sequence: MPTDTKRKAHDQEPTADSSDYDSDGSEEPDFINVDFDFRAPEEIDFQALKRLLQQLFYTHNTKLDLSSLADHVVKTSTTQGVGTTIKIVDDEDQDPYAFVSAITLSSEKKEGSEAANSLSKYLLEVTSKPSSKSVHDVIKSAASSTSTNAPVIAVLHERMVNMPPQVAPPLYKMLLEEVQASLVSTSATRPSHYLFFSRVFSADAFSDDEAMDEDDDDDDDEPSGLAGARKRKAKLARREAKKAGAKKDAPKSRTISDGMALAGSSDEELGLFHPEDIAISKFASNSLTYRFPPPPDASDSFEAPLFGRIALVPADKMDALLQQIETDLSMPAPQ
What is the function of this protein?
Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
What are the official names of this protein?
Protein BCP1.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL22_METTH
Sequence: MAKVKYAYKEEDRSGTARASATHLKISPKHAVEICREIRGMELEKAKKYLEEVIRMERPVAFKRYNRKVGHRRGLNGWASGRYPVKAAGQILKVLENAEANAEYKGLDTEKLRIIHISSHRGPVIRGWIPRAFGRATPFNTPTTHVQIVLGEA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DXR_CAMJ8
Sequence: MILFGSTGSIGVNALKLAALKNIPISALACGDNIALLNEQIARFKPKFVAIKDSKNKHLVKHDRVFIGQEGLEQILTECQDKLLFNAIVGFAGLKSTLKAKELGKNIALANKESLVVAGSFLKGVKFLPVDSEHAALKFLLEGKKNIAKLYITASGGAFYRYKIKDLNQVSVKDALKHPNWNMGAKITIDSATMANKLFEIIEAYHLYDFKEIDALIEPRSLVHAMCEFKNGASTAYFSKADMKLAISDAIFEKQDTPILEAVDFSKMPALKFHPISTKKYPIFKLKNTFLKEPNLGVIINAANEVGVYNFLENKSGFLDIAKCIFKALDHFGVPKISSIEEVFEYDFKTREYLRS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RUTD_ECO55
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: HEM6_BORPA
Sequence: MTAVAIPAVRDYLTDLQGRIVAALEQAGGEAFRTDAWQRAEGGGGVSRLLEGGQLFERAGVLFSHVKGTRLPPSASAHRPELAGRGWEAMGVSMVLHPRNPYVPTTHMNVRMFVAAARPGHAESDVFWFGGGLDLTPYYPFEDDARHFHRACRDALDPHGADYYPRYKQWCDEYFFLKHRNETRGIGGIFFDDLNDPGFDASFALTRSVGDSFLPAYLPIVQARRDMPYGERERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILLSMPPLAQWRYDWQPQAGTPEAALAEFLRPREWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBAN_SHIFL
Sequence: MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSPRFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLLVILACLLFYMWRIPVIDEKQEKH
What are the official names of this protein?
Inner membrane protein YbaN.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBL_CUCSA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SFSA_SERP5
Sequence: MIFSPPLHHATLIKRYKRFLADVITPEGETFTLHCANTGAMTGCATPGDTVWYSTSDNPKRKYAHSWELTHTQQGDWICVNTLRANTLVREAIEQNLVNELSGYSKISSEVKYGSESSRIDLLLQAEDRANCYIEVKSVTLLQQQRGYFPDAVTLRGQKHLRELLSVVESGQRAVLFFAVLHSGIEQVAPAHHIDERYATLLAQVQQLGVEVVCYGAKLSPDGIYLCDKLPFFID
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: URED_PSEA7
Sequence: MTAALPDLSFHPAWHAQLELAYARAGDATRPVTRRHAGPLRVQKHLYAEGPEVCQHILVHPPGGIAGGDSLAFDVRLGERAWAQLTSPGAAKWYRAACPSRQTLEIHLEPGATLEWLPQESIVFAGAQAELETRIQLRGDARLFYWDMVALGRPASGERFASGHFVAALDIRRDDRLLWHERQRIDGGDRLLDSPIGLAGHPVLATLVASGEIDTDLLQRCRALPCAGRGNLSQLPGGLLVARCLADEALHARAWLIELWRLLRPALLGREAVPPRIWST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_ALIFM
Sequence: MRTHYCGNLNKSLAGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMKDVFEVASQLRNEFCIKFTGEVRVRPDSQVNKDMATGEVELLATGLEIINRSAALPLDFNQTNSEEQRLKYRYIDLRRPEMSDRIKLRARASSFVRRFLDENLFLDIETPVLTKATPEGARDYLVPSRVHKGSFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMTSQEVRNVTERLVHDMWKELLDVELGQFPVMPFSEAMRRFGSDKPDLRNPLELVDVADLVKDVDFKVFSGPANDEKGRVAVIRVSGGASLSRKQIDEYGNFVGIYGAKGLAWMKVNDRAAGFEGVQSPVAKFLNEEVINAILERTQAETGDIILFGADKAGIVSEAMGALRLKLGTDLELTDTSAWAPLWVVDFPMFEEDGEGNLHAMHHPFTSPLGVSAEELQANPAAANSDAYDMVINGYEVGGGSVRIHNAEMQTAVFGILGIEAQEQQEKFGFLLEALKYGTPPHAGLAFGLDRLAMLLCGTENIRDVIAFPKTTAAACLLTDAPSLANPASLEELAIAVKLAEKKDA
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K81_HHV8P
Sequence: MSSTQIRTEIPVALLILCLCLVACHANCPTYRSHLGFWQEGWSGQVYQDWLGRMNCSYENMTALEAVSLNGTRLAAGSPSSEYPNVSVSVEDTSASGSGEDAIDESGSGEEERPVTSHVTFMTQSVQATTELTDALISAFSGSYSSGEPSRTTRIRVSPVAENGRNSGASNRVPFSATTTTTRGRDAHYNAEIRTHLYILWAVGLLLGLVLILYLCVPRCRRKKPYIV
What are the official names of this protein?
Protein K8.1.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: EPMA_ECOBW
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: EX7L_YERE8
Sequence: MSQSSASSIFTVSRLNQTVRQLLEMEMGQIWLTAEISNFSQPSSGHWYFTLKDDRAQVRCAMFRNTNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPSPAKQVGVITSSSGAALHDVLQVLQRRDPSLPVIIYPTAVQGADAPLQIVRAIQLANLRGECDVLIVGRGGGSLEDLWSFNDERVARAIFNSRIPIVSAVGHETDVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRHQQLTRLEHRLQQQHPHLRLARQQTLLLKLQRRLEDSAQNQIRRLSRRTERLQQRLVQAQPQGQIHRYNQRVQQQEYRLRQALERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPEGSLLKTTKQVHTGDKLTTRLQDGWVESEITQIKVAKKPRQRKAAN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STAA3
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_RICM5
Sequence: MTRVKSGKISKNRHKKILKLAKGYRGRANSCFRVAIEKVEKALQYAYRDRRNRKRDFRGLWIQRINAAVREHELVYSQFMGALKKAGIDINRKVLAELAVNNSDGFVSIVEKAKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FHUB_ECOLI
Sequence: MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSPDIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLGITVTTLWAIPGAMASQFAAQAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAINQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLDDGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPRLMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDMKVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWPRIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWLLPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQVLTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTRIALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFADWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR
What is the function of this protein?
Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import.  Responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Iron(3+)-hydroxamate import system permease protein FhuB, Ferric hydroxamate uptake protein B, Ferrichrome transport system permease protein FhuB, Ferrichrome uptake protein FhuB, Iron(III)-hydroxamate import system permease protein FhuB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.