PharMolix/UniProtQA huggingface dataset:
Protein: UMPS_CAEEL
Sequence: MSSLTDKTRNGALKRNLLRQMLKASVFKFGEFQLKSGQISPIYIDLRECFGHPGLLMLISEAISKQVEISEVQYAGVLGIPYAALPYASVAAGNYLKKPLLIVRKEAKSYGTKKLIEGLYQPNDRLILIEDVVTTGGSILDVVKVLHTENLVASDVFCILDREQGGRQKLQDAGVTLHSLLDMQTVLTFLYSTGAIGDEQWHGIVQALNLPYTSPTKLEINSELENLSSLPYVENVRTPLAERESLTESALIKKILGIMRRKKSNLCLAVDYTTVEQCLQMIELAGPFVLAIKLHADAITDFNEEFTRKLTTMANDMDFIIFEDRKFGDTGNTNLLQLTGAQKIANWADVVTVHAVQGSDSIAGVFRKLAKDPTYRLSGVLLIAQLSTKGSLTALEGYTETAVKIANENRDVISGFITQTRVSACSDLLNWTPGVNLDAKSDSAGQQWRGVDEAIEVQQNDIIIVGRGVTSSSEPVQQLKRYRQIAWDALTRSDDSI
What is the function of this protein?
Bifunctional enzyme which catalyzes the formation of UMP from orotate in the de novo pathway of pyrimidine biosynthesis (PubMed:19645718).  May also form UMP from uracil (PubMed:19645718).  Regulates the size of gut granules during embryonic development (PubMed:20148972).  Involved in resistance to DNA damaging agents including UV-C and X-ray radiation (PubMed:24262006).
What are the official names of this protein?
Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the OMP decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes near the apical surface of the embryonic intestine. Appears not to localize to gut granules.
Protein: RL24_YERPG
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNLALFNATTGKADRVGFRFEDGKKVRFFKSTSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YQC7_SCHPO
Sequence: MDPEYSELFERLNKQLDNVEDVLKPLKDAESIFELAEGKSELEQAKLYITMSYAINSTLYSFYKLNGIDASERPVMQELQRVKNYISKIQQAEKNVNPKTEAVNTSNAAISSSSSNRPKVAKDAATRIIKHHT
What is the function of this protein?
Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors.  Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites (By similarity).
What are the official names of this protein?
Exosome complex protein C1739.07.
What is the protein family that this protein belongs to?
Belongs to the C1D family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RRF_EHRCR
Sequence: MISEVKQDAKSRMEKSLSVYLSDIDGIRTGRARTSVLNGIVVETYGGRVKLNTISSVSVSDNKTLMIKVWDSNNIGAIKTAIMNSNLGFGISCEATTIRLTVPDMTQDMRKNLVKLLGKISEDCRVSIRNIRRDIMDRLKVMQDSKEISEDDLRVAGVEIQKITDDIMKKVNDAFTSKEKELLHV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CHLPB
Sequence: MNVIKDRLLAFIEDSFEEYSIERSASGEPDVFLVALLVKGTLPSRRVEVLAETDSGISVTRCMSIARWLRNAFEENEEIRNLVGEDYGLMVSSPGIGEPIQHARQYIRHKGHLLRVRYTDAGDAEHEVSGRLVEVEVVETTSPFIVLEPEKVSKGRKRERLEPVRLELNRIKSAVVEVEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CHLAA
Sequence: MSHTTVADRINELRSLIRRYDYHYYVLDDPIVSDAEYDALMTELRALEAAHPELITPDSPTQRVSGTPASQFAKVQHPQPMLSLGNAFTKADLLAWRDRVLRLLGPDAIVAYVVEPKIDGLAVALTYRDGRLVQGATRGDGEVGEDVTANLRTIGSIPLTLQATSTPQDDDLPTTLPTTIEVRGEVYMRTADFETLNDRLAAAGEKIFANPRNAAAGSLRQKDPTITAARPLRFFAYGVGVVEGISLSSQWQTLRYLRALGFPVNQDVRRFTDFAEVLAYCEAWMAKRDDLPYEADGVVIKIDDFAQQRELGVVGRDPRWAIAFKFPAREAITRLLDITVNVGRTGVVTPNAELEPVQIGGVTVRNASLHNADYIAQRDIRIGDYVIVKRAGDVIPYVVGPVIARRDGSERPWQFPTHCPACGSPLEREEGEAAWRCNNFSICPAQLVRRVEHFVSRSALDIVGMGERQAELFVQRGLIRDVADIFFLKADQLAELEGFGPKRIANLLAAIDAARQRPLDRLLVGLGIRYVGTVAAQTLVAALGSLDAIMAARQEELEQIPGIGPVVAASIVDFFSRPANRALIEKLRAAGVQMGGVSGPTRQSDTLAGKTFVLTGTLPSLSREQASALIVAHGGKVTDSVSKKTSYVVAGANAGSKLAKALQLGIPVIDEAGLLALIGTTAEPPPSPPPPPPETNTDGNQLLLPLDGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SL9A8_RAT
Sequence: MAEEFSNTTHESFNFTLHTTLGVTTKLVLPTPAEPILPVQTGEQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKVIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQADVISKLNMTDSFAFGSLISAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKHMSDVSGWQTFSQALGYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFPHKFEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLGLEPMEKRQLIGTTTIIIVLFTILLLGGSTMPLIRLVDIEDARARRRSKKDVNLSKTEKMGNAIESEHLSELTEEEYEAHYIRQQDLKGFMWLDAKYLNPFFTRRLTQEDLHHGRIQMKSLTNKWYEEVRQGPSGSEDDEQELF
What is the function of this protein?
Na(+)/H(+) antiporter.  Mediates the electoneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry.  Acts as an Na(+)/H(+) exchanger in the trans-Golgi.  Contributes to the regulation of pH regulation of Golgi apparatus, and consequently, in protein trafficking and endosomal morphology (By similarity).  In germ cells, plays a crucial role in acrosome biogenesis and sperm development, probably by playing a role in the fusion of the Golgi-derived vesicles that form the acrosomal cap (By similarity).  Can also be active at the cell surface of specialized cells (PubMed:22088432).  In the small intestine, at the cell membrane, plays a major physiological role in transepithelial absorption of Na(+) and regulates intracellular pH homeostasis of intestinal epithelial cells (PubMed:34288721, PubMed:18209477).  Acts as an important regulator of mucosal integrity in the intestine and in the stomach, could mediate the pH fluctuation necessary for mucin exocytosis or assist membrane trafficking of other proteins.  Plays a role in photoreceptor survival and in the maintenance of intracellular pH homeostasis in retinal pigment epithelium (RPE cells) (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 8, Na(+)/H(+) exchanger 8, NHE-8, Solute carrier family 9 member 8.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: GLMU_LATSS
Sequence: MVNKNAIILAAGKGTRMKSKLYKVLHEVCGRPMVDHVLTEVEKTEPATVVTIVGHGAEKVKDYLGDRSQYALQAEQLGTGHAVLQAEDLLKDQDGITIVVSGDTPLLTAGTFEKLFAYHHDKGAKATILTATAPDPTGYGRIIRNDIGIVEKIVEQKDTNDKEAAVNEINTGVYCFDNKTLFQALHEVTNENAQGEYYLTDVVEILKKKGEIVAAYKMPNFEESMGVNDRVALSQATKVMRQRINTAHMRNGVTLIDPESTYIEVGVKIGNDTIIEPNVVLKGNTTIGSDCFVGAGSTIIDSTIEDNIQITSSTIESAIMHTGSNIGPNSHLRPNAEIGVDVHVGNFCEVKNAKIGDRTKIGHLSYVGDATLGTDINVGCGVVFVNYDGVAKHHANVGSHVFIGSNSNIVAPVEIADHTFIAAGSTITDDVPEKAMAIARARQTNKENYWAKLPVAKDEEWQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPS8_PONAB
Sequence: MNGHISNHPSSFEMYPSQMNGYGSSPTFSQMDREHGSKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPDALRMISNADPGIPPPPRAPAPAPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQKFKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLLNKDTIDFLNYTVNGDERQLWMSLGGTWTKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATMEQDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGEAAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAPSPPPTPAPVPVPLPPSTPAPVPVSKFPANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFNPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQKAALEDSSGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH
What is the function of this protein?
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture.  Depending on its association with other signal transducers, can regulate different processes.  Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity.  Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context.  Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction.  Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions.  Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion.  Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity.  In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation.  Component of a complex with WHRN and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core.  Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes (By similarity).
What are the official names of this protein?
Epidermal growth factor receptor kinase substrate 8.
What is the protein family that this protein belongs to?
Belongs to the EPS8 family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, ruffle membrane. Cell projection, growth cone. Cell projection, stereocilium. Synapse, synaptosome. Note=Localizes at the tips of the stereocilia of the inner and outer hair cells (By similarity). Localizes to the midzone of dividing cells.
Protein: Y018_MYCGE
Sequence: MTVAEIKKLALNNQVFNEAKALLEKGNVIFPKKFLKRKKIIIEVLDGKVFKVQINLKTAAAHLDCSCSNDKQNCVHIIAALLKYNDLKNQDNKEFDLNKADKLECKEVEILIENVSLAIVNGSWKLKIGFVINIDKVQTNTTALRFYCCDNKDVYFLHTEDEQLFRIALDKFNSVERQTLLIFDQLNKTKQMQYENNSLLFNLDQFLSLVKEVKKPSLFLLNEDKTDNILFLRSQHKINGLSHVCGFLNNKVFDFVSYNEKTKQIVLRLAYLNKFTDFKFPYNINIYKLAFGETLFFHFLIHLKMNGFKNIFFQSDVVIVKESEYLPKMFLTIEFNTQKNKFITDAFFKYKNKNSNTLTTVYPHRYYLAQKTNTSNFNRLLFYEQALQRFYEELFQIDYLRRFENIPIKDKNQIALFKTVFDDYKTIDLAELKLTSNLLNYKQLHFSISDIKALKIEDRQLKIEFKAGGIDLKLIKSVLSNYYKGNAICIGEDGWYDLNDENAKALISFWSQIDLRNATCDANNNLLLAKYHLFEVVDTISKYTDVTNLLDEKTALQLKIASENQFHLSLDNNQINNLRKYQKEGVKWIRALEDNQFGGILADEMGLGKTAQVIFAMLDSYQSTKSLLPSLIIVPASLLLNWKSEFQKFAPHVKIVTANGNFKERSQVYESLKNQILLMSFNVLRSDIKWISQKKFHYVVIDEAQGIKNENSTVTKAAKKIKGNFCLALTGTPIENRLLDLWSCFDFVLPNFLGNKKQFSDQFEKEKNDESFQKLMKKTSPFILRRTKNKVLKELPKKIITDIYVELSEEHQKLYDKQKTDGLKEIKESDAKNALNILSLILKLRHICSLVKDNDVNDFEDNSKANAALNIIYEALENKRKVILFTQFLDVIDCFKQTLKNQKIDHLVFDGRKTVKNRNTIIQKFNSAKEPCVMLASLKAGGVGINLTAAEVVIHFDVWWNSAVENQATDRAHRIGQSKTVQVYRIIAKNTIEERVCQVQNQKQELVKKTLVEDVNFFKSLSHEELLKLFE
What are the official names of this protein?
Uncharacterized ATP-dependent helicase MG018.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
Protein: DNLJ_XYLFA
Sequence: MIPLDPAQRAAELRCRLQEANYHYHVLDQPRIPDADYDRMLRELDALEAAYPDLATPDSPTQRVGHTIATAFSEVRHTVPMLSLNNAFSDPEVLEFVRRITACLGETAPGFSAEPKLDGLAISLRYQNGIFIQGATRGDGVTGEDVTANLRTLPTIPQRLQSDTWPTVLEVRGEVYMPRPDFEAYNTQARLRGWKVLANPRNGAAGSLRQLDPHITAQRPLSFYAYGIGEVTDDVSFHRHSEILASLRAWGFPVSPLVELVYGSEELLNYYRRMETIRDTLPFDIDGIVYKLDDLSGQREMGFVARAPRWAIAHKFPAQEQTTTVEAIEIQIGRTGAATPVARLTPVQVAGVTVTSATLHNADQIARLDVRIGDTVIVRRAGDVIPEVVTVITDSRPLGATAWSMPMACPVCGSEIVRETGAAVWRCSGELACPAQRKEAIRHFVSRRAMDVEGLGVKCIELLVDAAVVHGVADLYHLSLDQLLRLRLVTNAQTPTMLLREARDHVTGMRYQQLEEILRTVGVDLSGEGDVPKHWQIDVLRAQWPDFDWNHKKIATKWAQNLIAAIDRSRQTTLERFLFALGMTHVGETTAKALAHSFGDLAIIRQLPWPLFKCVPDIGGEVARAIGHFMDQPANQQAIDDLVERGVRITDTHPPTSTLRDQLTLASLLEHLDIPKITPLRAVQLAALAPTLPLLAEAALDTLLQAGVSQPAAQSLTEWFQSPDNISLARRLQHCCDVLLAQLPSADRAHTAPLNGQSVVLTGKLASLTREAAATRLEMLGAKIVGSVSKKTSFLVAGEDPGSKLDKAHALHVDIWDEARLLAFLGQYSAQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSYR1_ARATH
Sequence: MIDEKMRSKSIGPFVRQVKPLSPHMVLFVLLYVLSISVFFLTVSEAVCNLQDRDSLLWFSGNVSSPVSPLHWNSSIDCCSWEGISCDKSPENRVTSIILSSRGLSGNLPSSVLDLQRLSRLDLSHNRLSGPLPPGFLSALDQLLVLDLSYNSFKGELPLQQSFGNGSNGIFPIQTVDLSSNLLEGEILSSSVFLQGAFNLTSFNVSNNSFTGSIPSFMCTASPQLTKLDFSYNDFSGDLSQELSRCSRLSVLRAGFNNLSGEIPKEIYNLPELEQLFLPVNRLSGKIDNGITRLTKLTLLELYSNHIEGEIPKDIGKLSKLSSLQLHVNNLMGSIPVSLANCTKLVKLNLRVNQLGGTLSAIDFSRFQSLSILDLGNNSFTGEFPSTVYSCKMMTAMRFAGNKLTGQISPQVLELESLSFFTFSDNKMTNLTGALSILQGCKKLSTLIMAKNFYDETVPSNKDFLRSDGFPSLQIFGIGACRLTGEIPAWLIKLQRVEVMDLSMNRFVGTIPGWLGTLPDLFYLDLSDNFLTGELPKELFQLRALMSQKAYDATERNYLELPVFVNPNNVTTNQQYNQLSSLPPTIYIKRNNLTGTIPVEVGQLKVLHILELLGNNFSGSIPDELSNLTNLERLDLSNNNLSGRIPWSLTGLHFLSYFNVANNTLSGPIPTGTQFDTFPKANFEGNPLLCGGVLLTSCDPTQHSTTKMGKGKVNRTLVLGLVLGLFFGVSLILVLLALLVLSKRRVNPGDSENAELEINSNGSYSEVPPGSDKDISLVLLFGNSRYEVKDLTIFELLKATDNFSQANIIGCGGFGLVYKATLDNGTKLAVKKLTGDYGMMEKEFKAEVEVLSRAKHENLVALQGYCVHDSARILIYSFMENGSLDYWLHENPEGPAQLDWPKRLNIMRGASSGLAYMHQICEPHIVHRDIKSSNILLDGNFKAYVADFGLSRLILPYRTHVTTELVGTLGYIPPEYGQAWVATLRGDVYSFGVVMLELLTGKRPMEVFRPKMSRELVAWVHTMKRDGKPEEVFDTLLRESGNEEAMLRVLDIACMCVNQNPMKRPNIQQVVDWLKNIEAEKNQNNREEPEEEEET
What is the function of this protein?
Tyrosine-sulfated glycopeptide receptor with a serine/threonine-protein kinase activity (PubMed:17989228, PubMed:25267325).  Regulates, in response to tyrosine-sulfated glycopeptide binding, a signaling cascade involved in cellular proliferation and plant growth (PubMed:17989228).  Not involved in PSK perception (PubMed:17989228).  Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances (PubMed:23062058).  Mediates activation of the plasma membrane H(+)-ATPase by PSY1 (PubMed:25267325).  Phosphorylates AHA2 at Thr-881 (PubMed:25267325).
What are the official names of this protein?
Tyrosine-sulfated glycopeptide receptor 1, PSY1 receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLYA_OCEIH
Sequence: MEFVKQADTEVFEAMQAEKNRQQDKIELIASENFVTKAVMDAMGSILTNKYAEGYPGKRYYGGCEHVDVVENLARDRAKELFGADHANVQPHSGAQANMAVYSAVLEPGDTVLGMNLNHGGHLTHGSPVNFSGQLYNFVDYGVDKETEQLDYDAVLEKAKEVKPKLIVAGASAYSRSINFAKFREIADAVDAYLMVDMAHIAGLVATGEHENPVPHADFVTTTTHKTLRGPRGGMILCKEEFAKKVDKAIFPGIQGGPLMHVIAAKAVSFKEALSDDFKAYSKQIVANAKLLGEALNKEGIRIVSGGTDNHLLLLDVTPLQLTGKVAEKALDDIGITTNKNTIPFDQESPFVTSGIRIGTAAVTTRGFGEEEMKEIASIISLTLKHHEDEAKLKEAAQRVQALTEKFTLYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_YERPY
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: Y1086_YERPP
Sequence: MYPVDLHMHTVASTHAYSTLHDYIAEAKLKNIKLFAITDHGPDMADAPHYWHFMNMRVWPRLVDGVGILRGIEANIKNLDGDIDCTGPMLDAVDLLIAGFHEPVFPPQDKAANTQAMIATMAQGNVHIISHPGNPKYPVDIPAIAQAAAKYNVALELNNSSFAHSRKGSEANCRAIAAAVRDAGGWLALGSDSHIAYALGIFEHCERIIAEVNFPQERILNVSPRRLLDYLEQRGRPAIPELAEL
What are the official names of this protein?
Probable phosphatase YPDSF_1086.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: RS11_STAAT
Sequence: MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y2746_CHRSD
Sequence: MLTTTLLFIATAMAEIIGCYLPWLWLRQQGSPWLLVPAAASLTLFVWLLSLHPAASGRVYAAYGGVYVVCALVWLWGVDGEALRPTDWIGAALALTGMGVIASGWR
What are the official names of this protein?
UPF0060 membrane protein Csal_2746.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPC2B_CHLRE
Sequence: MSGQFTISDLNRLYQRIIYRNERLKKFLKDPALSSSFEMKYAQRLLQEAVDNLIQNGKSGVVPEKDARGRLLKSLSDILKGKQGRFRQYLLGKRVDYSGRSVIVVGPRLRLHECGIPKEMALVLYSPFLIKRILNEKLADTYLSAKKLIRTNPLLVSQLLREIMKSCPVLLNRAPTLHRLGFQAFQPKLVDGKAILLHPLVCPAFNADFDGDQMAVHVPITFEARAEAWKLMLARNNLLSPATGEPLILPSQDMVLGCYYLTTNCAEKWSKLKKGSGMYFHNIHEVLKAYNQHLIHLHAVIWVNIQGHLETANNIEQPLEIRIPLNQKYFYSQKGSYTALAGRPWQLLLREDAYSSNGLIAEANAGNLPQINVAEGEVNKNILDLRYLNLNYMEIYSKTHNLLNVNHSTLVAQRGQIKDNIHLPQLTTQIIRTTPGKILFNIIVKNAIEKRPKLLSKSNFKGGFIKNKLVNAIDQEIDNYFIRKNTALS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta' C-terminal section, PEP, Plastid-encoded RNA polymerase beta' C-terminal section, RNA polymerase beta' C-terminal section.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADO2_ORYSJ
Sequence: MAMATIPEVPASALLPTMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENRMKENLDIFDWELTEEERDKISKLPQQRGLTGMQFVCDNGPYKCVEDLWDGA
What is the function of this protein?
May play a role in auxin-induced cell growth by generating hydroxyl radicals, which tends to increase cell wall loosening.
What are the official names of this protein?
Probable NAD(P)H-dependent oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: DLTC_STRSY
Sequence: MDVKETILNIIEELFMEDVSEMMDEDLFDAGVLDSMGTVELIVELESRFNITVPVSEFGREDWNTANKIISGVVELMHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AA3R_BOVIN
Sequence: MPVNSTAVSLASVTYISVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGVTIHFYSCLLMTCLLMIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADKNLTFLPCQFRSVMRMDYMVYFSFFTWILIPLVVMCAIYFDIFYVIRNRLSQNFSGSKETGAFYGREFKTAKSLSLVLFLFALSWLPLSIINCIIYFNGEVPQIVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVICQPSKSMDPSIEQTSE
What is the function of this protein?
Receptor for adenosine.  The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.
What are the official names of this protein?
Adenosine receptor A3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSR4_ARATH
Sequence: MEGSKLLPCVHKSPVPTSHQLYINYEILGLTKLKKHKYTQNKMSSSDSSSAESRLATAKTVLTTAASVAATAMLARSLVQDYLPDEVHHYISYGFRSIFGYFSSQMTIIIEEFEGFAHNEVFEAAEAYLATKISPSNKRIKVSKHEKENNYNVTVERDEEVVDTYNGVKFQWILHCRHVESKHFHNPRDLNSTLRSEVRSFELNFHKKFKDVALESYLPFMVKRATLMKQEKKTLKIFTLSPENMYGNYSDAWTSVTLDHPSTFKTLAMDSDVKTSVMEDLDKFVKRRDFYKRVGKAWKRGYLLYGPPGTGKSSLIAAMANHLNFDIYDLELTAVNNNSELRRLLIATANRSILIVEDIDCSLELKDRTSDEPPRESDDIEDPRYKKVTLSGLLNFIDGLWSSCGDERIIIFTTNYKEKLDAALLRPGRMDMHIHMSYCTPSTFKALALNYLEIKEHRLFSKIEEGIEATEVTPAEVAEQLMRNDSVDKVLEGLIEFLKVKKIENEQDKAKTEKQELENKKKTKEGTDSVVKKEVDEQLVRNDRVDKVLEGLVELLKAKKIEDDQDKAKHEEVEQH
What are the official names of this protein?
Protein HYPER-SENSITIVITY-RELATED 4, AtHSR4, BCS1-like protein.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.