PharMolix/UniProtQA huggingface dataset:
Protein: RH58_ARATH
Sequence: MASQLLNVPHLAFFPKISYASVFSTLKPSFFHSTSTRRALKSSPSSRIINLQAVAETSSEIESNSVTETTVPLTLRQICQGFVPEHILHRMEEIGFVFPTDIQREALPTLFTGRDCILHAQTGSGKTLTYLLLIFSLINPQRSSVQAVIVVPTRELGMQVTKVARMLAAKSEIDVKGCTVMALLDGGTLRRHKSWLKAEPPAILVATVASLCHMLEKHIFRIDSVRVLVVDEVDFLFYSSKQVGSVRKLLTSFSSCDKRQTVFASASIPQHKHFVHDCIQQKWTKRDVVHVHVSAIMPMPLCLLHRFVMCEKTNKHQVLLALLESDAPESAIIFVGEQSEKSKKAGNDPSTTLLMEFLKTSYKGSLEILLLEGDMNFNSRAASLTEIRQGGGFLLVSTDIAARGIDLPETTHIFNFDLPQTVTDYLHRAGRAGRKPFSDRKCIVANLITSEERFVLQRYENELMFSCEEMML
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 58, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RRP7B_HUMAN
Sequence: MEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSQKELLNYAWQHRESKMEHLAQLRKKFEEDKQRIELLRAQRKFRPY
What are the official names of this protein?
Putative ribosomal RNA-processing protein 7 homolog B, Putative gastric cancer antigen Zg14-like protein.
What is the protein family that this protein belongs to?
Belongs to the RRP7 family.
Protein: HEM3_MOUSE
Sequence: MSGNGGAATTAEENGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNEVDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDELQEFSAIVLAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVSVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGPEDDPQLVGITARNIPRGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR
What is the function of this protein?
As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen.  Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen.  The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled.  In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact.
What are the official names of this protein?
Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YDHI_SHIFL
Sequence: MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLLRGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW
What are the official names of this protein?
Uncharacterized protein YdhI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOC1_EMIHU
Sequence: MDRSFDYVKINLASPSRIREWGERKLPNGQVVGEITKPETINYRTLKPEMNGLFCERVFGPVNDWECHCGKYKRIRHKGIVCERCGVEIIDSKVRRHRMGFIELASSVTHVWYVKGRPSKIALILGMTVKELEQIVYFNSYVVTKANKDLNLSYQQLLSEADWLAIDYNDDFSLKENTISIGAEAIKTLLKNVDLQQSASEIRELLPFAKRFFSEKLIRRLRVINQFIASKFDPTWMILDILPVLPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIVAPELIIRNEKRMLQEAVDALIDNGKRGRAVVGLNNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIIVGPELKLNQCGLPSEMAIELFQPFVIHRLIYEGLVNNIKAAKSIIQKNGPLAWEILANVMEGHPILLNRAPTLHRLGIQSFEPILVSGRAIRLHPLVCPAFNADFDGDQMAVHIPLSLEAQSEARLLMLAPNNFLSPATGDAILTPSQDMVLGCFYLTANNPSQQLNKNHYFSDFEDAILAYQNSQIHLHTFIWVRCNNVDLTEDETCSQTQSGNLILTHGADIKSKQSSSQDTKTKYIRTTPGRILLNEIFQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRDR_GLUOX
Sequence: MRCPFCGHDDTQVKDSRSTEDGVAIRRRRVCSACTQRFTTVERVQLRELSVTKADGRRVPFDRDKLARSIRVALRKRPVPEERQERLVNGLVRQLEASGEHEISSHRIGQLAMDALREVDGVAYVRFTSVYRDFREVEAFSKILADMKPIPGETDTPSPDDSQETP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DCDB_TROW8
Sequence: MLLSDVDIQAALEDKLIQIDPFDPQMLQPASLDIRLSRYFRLFNNHTYAYIDPAEPQEALTRLVEVAENQAFVLHPGEFILGSTCETVSLSNDLAARLEGKSSLGRLGLLTHSTAGFIDPGFSGQITLELGNVATLPIKLWPGMKIGQLCFFQLSSPAKNAYGSPVCASRYQGQRGPTASLSHQHFYRARFTEIGL
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: FIS_ECOHS
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: HIS1_RHIE6
Sequence: MTITIALPSKGRMKDDASAIFERAGMPITAVGNDRSYRGRVEGWDDVEVAFLSASEISRELGNGTVDFGVTGEDLMREGFAEVDKRVEFCARLGFGHADVVVAVPEIWLDVETMADLGDVAADFRARHSRRLAIATKYWRLTQQFFSSQHGIQLYRIVESLGATEGAPASGSADIIVDITSTGSTLRANHLKVLQDGVILHSQACLVRARKESHADEPVVQAIIEAVRAAL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_LIMF3
Sequence: MSGRFISFEGPDGAGKTSVLTAIRTGLVNQLGDQVVYTREPGGNPIAEQVRAVLLDKQNGAMDDWTEALLYAASRRQHVVETLKPALEAGKLILCDRYLDSSIAYQGGGRELGIDRIWELNQYAIDGLLPDLTIFLDLPVETGLARIEKGRAETINRLDEQTTNFHRRVRQAYLTLAERFPERIVKVNADQELARVIEDVRSAIHARYADLFTN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ZP2_BOVIN
Sequence: MACRQRGDSGRPSSWFRADWRSFFLSFTLLTSVNSIDVNQLDPAFPGTVTCYENRMVVEFKRTLGNKIQHASVVDSLGLKMLNCTYVLDPEKLTLKAPYESCTKRVLGQHQMTITFMNDNTAHRQKTVLYHVSCPVMQAGRHDQHSGSTICSKDFMSFTFHFFPGLADDTAGPKPQMGWTVTVGDGERAQNLTLQEALTQGYNLLIENQKMSIQVLFHATGVTHYSQGNSHLYMVPLKLTHVSPGQTIILSSRLICASDPVTCNATHMTLTIPEFPGKLKSVSFENKNIAVNQLHNSGIVMEIANGLRLHFSKTLLKTKFSEKCLPYQFYLSSLKLTFYTQLETVSMVIYPECVCESTVSIVSGELCTQDGFMDVEVYRHQTKPALNLDTLRVGDSSCQPTIKAPFQGLVKFHIPLNGCGTRHKFENGKVIYENEIHALWADLPPSTISRDSEFRMTVRCYYSSSNMLINTNVESLPPPVASVKPGPLALTLQTYPDNSYLQPYGDKDYPVVRYLRQPIYLEVRVLNRTDPNIKLVLDDCWATSTMDPASLPQWNIIVDGCEYNLDNHRTTFHPVGSSVAYPNHYQRFAVKTFAFVSEDPAFSHLVYFHCSALICDQLSSNFPLCSASCLVSSRSRRATGATEEEKMIVSLPGPILLLSDGSSFRDAVDSKGHGTSGYAAFKTMVAVVALAGVVATLSLISYLRKKRITVLNH
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP2 may act as a secondary sperm receptor.
What are the official names of this protein?
Zona pellucida sperm-binding protein 2, Zona pellucida glycoprotein 2, Zp-2, Zona pellucida protein A.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPA subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 2]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: Y350_CUPPJ
Sequence: MRIILITGISGSGKSVALNVLEDAGFYCVDNLPAQFIPDLARYLASEGYTHLGVATDIRSRESLEHLPDTVRELAETHQVEVLFLTASTDALVQRYSETRRRHPLSILTDGVPGSDGEPAFNDRALMEAIEMERELLSPLAESAHRIDTSNVRTNTLRSWIKELIREDSERLTLLFESFGFKHGVPSDADLVFDVRSLPNPYYDLALRPLTGRDGPVIDFLQAQPMVLAMAEDIRAYVEKWLPSFIADNRSYLTVAIGCTGGQHRSVYIAERLANYFRAHGNVLVRHRELAPAT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Reut_A0350.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ATAT_BOVIN
Sequence: MEFPFDVDALLPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSASRMQSNRHVMYILKDTSARPAGKGAIVGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESLQRHGHGRELFQHMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHPPARKLPPKRAEGDIKPYSSSDRESGLPQGW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  Required for normal sperm flagellar function.  Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells.  May facilitate primary cilium assembly.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: IPCS3_ARATH
Sequence: MPVYVDREAPKLWRRIYSEATLEASLLAEKWKLVLAGLVFQYIHGLAAHGVHYLHRPGPTLQDAGFFILPALGQDKAFFSETVFVTIFGSFILWTFHPFVSHSKKICTVLIWCRVFVYLAASQSLRIITFFATQLPGPNYHCREGSKLAKIPPPKNVLEVLLINFPDGVIYGCGDLIFSSHTIFTLVFVRTYQRYGTRRWIKHLAWLMAVIQSILIIASRKHYTVDIVVAWYTVNLVMFYVDSKLPEMAERSSGPSPTPLLPLSTKDSKNKSKEDHQRLLNENNVADDH
What is the function of this protein?
Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis.
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase 3, Inositol-phosphorylceramide synthase 3, AtIPCS3, IPC synthase 3, Protein ERH1-like1, Sphingolipid synthase 3.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YNFU_ECOLI
Sequence: MSERKNSKSRRNYLVKCSCPNCTQESEHSFSRVQKGALLICPHCNKVFQTNLKAVA
What are the official names of this protein?
Putative zinc-binding protein YnfU.
Protein: ADDA_BACLD
Sequence: MEISKPKGSTWTDDQWKAIVSSGRDILVAAAAGSGKTAVLVERIIRKITDQERPVDVDRLLVVTFTNASAAEMKHRIGEALEKELAENPGSLHLRRQLALLNKASISTLHSFCLQVIRKYYYLIDVDPAFRIADQTEGELLGDEVLDELFEEEYKKGNPAFFELVDRYTTDRHDLDLQHLVKRVYEFSRSHPDPEGWLHSLAELYDAASDTKVEALPFYSYIKEDIALVLEGMRQKLTRALDLTKQPGGPAPRAENFLDDLAQIDRLIQQQDDFSALHELVPTVSFQRLKPCKGDEYDPRLVDEAADLRNSAKKQLEKLKSDYFSRTPEQHLESLREMKPVIQTLVQLVLEYGRRFAEAKKEKAIVDFSDLEHDCLAILSVKNPAGEAVPSEAAKFYRHQFHEVLVDEYQDTNLVQEAILKLVAKEEHEGNLFMVGDVKQSIYRFRLAEPLLFLSKYKRFTDDGSGSGQKIDLNKNFRSRSDILDSTNFLFKQLMGEKVGEVEYDEQAELKLGASYPPNEATKTELLLIETPSGAPGEEAEELEAVQLEARAMAGQIRRLITEKFQVYDAKAKASRNIQYRDIVVLLRSMPWAPQIMDEFKQQGIPVYANLSTGYFEATEVSVTLSLLKIIDNAYQDIPLASVLRSPVVGLDENELSLIRIKDKKAPFYEAMKAYLAAADGDERLSEKLRRFDGLLKKWRAYAKNHSVAELIWEIYRDTKYLDYVGGMPGGKQRQANLRALYDRARSYEATSFRGLFRFLRFIERMQERGDDLGTARALSEQEDVVRLMTIHSSKGLEFPVVFTAGLGRNFNMMDLNKSYLLDKELGFGTKFIHPKWRISYPTLPLIAMKKKLRRELLSEELRVLYVALTRAKEKLYLVGTAKDKEKLLADWRTQAAGSEWLLPDYERFQAKSYLDFIGPALMRHRDMDESGAPPVIDEIREHPARFQVSWLSAADLQAEAVDQAGEERHDRLVQIQMGHAIEGAFEYEQQVRERLAWSYPYKDAAKVRTKQSVSEMKRQKEYEDEYGDRSLIRPSQEALLFKRPSFMMAKGLTAAERGTAMHTVMQHIPLTRTPEKNELSRLLDRLVEKELLTEDQRAAIEEDDILAFFDTEIGQKLFGARRVEREVPFNMTLSAKEVYPDLESADEPVLIQGIIDCLFETEDGFYLLDYKTDRIHGKYRNGFEGAEPILRKRYETQIQLYARAVETMIKMPLKGRALYFFDGGHVLLF
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: KKCC1_HUMAN
Sequence: MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSRLLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAEDCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNLLVKEGFGEGGKSPELPGVQEDEAAS
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes.  Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4.  Involved in regulating cell apoptosis.  Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase kinase 1, CaM-KK 1, CaM-kinase kinase 1, CaMKK 1, CaM-kinase IV kinase, Calcium/calmodulin-dependent protein kinase kinase alpha, CaM-KK alpha, CaM-kinase kinase alpha, CaMKK alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YO01_BPL2
Sequence: MLMMVIRIYIHKRLNAKDYNNFYTSIGDFGYTIPGSDAPQYNIESDSEHYLNFGIAHINFNNGTNNQITNPNPEVYTRFYIQMKTPDGQDRIVYEAENANAISFLIRSTYHKPMSGLVGGFRFDPLLGIRVYKDSFVLADELARIQSEFTTVYGNSGINVTENTTNYSVRMYWESAVVVEPGEPSPENPIPWLSNLPNITDGNPENIDGQWGNVTGFNYNPTTKLFNADVIYDGNSYPIRDAVVASNDDSFLTRTEKAYYFTQGGQKFLYLNFSKDIDSFMFKNHYSELKNWVGHALWNLSTGEVNVMEQLKVFQYLKFTEDNELMAYFYIVDTPVDDLISVTSNVAYRYWKPTWFGLGPKEPGPIQNKIITAAQGEFNSIRPTWVKPVYLGSYFAGASGLVIAGSALIKGGSPWFGLGLAGVGILAGGILQYADDNEWLNYDIAQVQKLEPNVNIRSEISEAYFNAYGQMFPSTLGQSLYRISYGQFDQSDLQVISDKSDVITVVFETDGITHTYQKDQIDDTWDGPATEIPLGVDGILPEWALWLITIVIGLFALSNLQKIFDTIKKKPIISIIVVIAILYALTYFNLL
What are the official names of this protein?
Uncharacterized 66.6 kDa protein, ORF1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COPT4_ORYSJ
Sequence: MAMPMPMPPPGPGGDAPPAPTMMPGMAMPMTTGMSFTWGHRAVVLFPRWPGDRAGVGMYFLCLLLVLALAALAEALSAASRRLDLDLDLSRSRGRRRRRRQQLLAAGVHAARMGLAYLVMLAVMSFNAGVLLAAVAGHAAGFLLARSGLLGSRAAAPEIDGAAAAAAATSNGSSLHPSSEPKP
What is the function of this protein?
Involved in the transport of copper.
What are the official names of this protein?
Copper transporter 4, OsCOPT4.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUFY1_MOUSE
Sequence: MAARGECRRAGQDSEPEPEREPESEPGPEPEPQAGLESGEAFEIVDRSQLPSPGELRSASRPRVADSWSAPILTLARRATGNLSASCGSALRAAAGLGDGGGGGERAASKGQMMEERANLMHMMKLSIKVLLQSALSLGRSLDADYAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCPEASDIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKQLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKGEDLDSQVGVIDFSLCLKDAQDLDSGREHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQKEQQQLREQNEVIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKVQSAESSLQQKNEAIASFEGKTTQVMSSMKQMEERLQQAERARQAAEERSHKLQQELSGRGSALQLQLSQLRDQCSGLEKELKSEKEQRQALQRELQREKDTSCLLQTELQQVEGLKKELRELQDEKAELRKVCEEQEQALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKDFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDSCHTLLLQRCSSTAS
What is the function of this protein?
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
What are the official names of this protein?
RUN and FYVE domain-containing protein 1, Rab4-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
Protein: PER6_DAUCA
Sequence: LVSGCADLTALAAR
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 6.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Protein: FC6_PHOAM
Sequence: MSPPSQIKPPQGTTPVPPSELDPRSDEEIVRSISAHVKPTDSEKNMWAYWHSGWENMPPWTKRNVVHWARMLGTEWTVRVLDGIPGSANYYERFVPPHLLPSAMRERRMSGPYVATHSADFVRLPLLFLYGGCWLDVGAILVRSIQDVWDVLADPKQSYEFAAFTYMMRPGEASIINTWMMGRKNMELLRRWHDTFLHLWGDKSSCDGLHKHPLLSHLRPLSSLTHGLITDENNEPVAKTDKIIDYGAQVYCLDRLRDLVDTNDGWNGRQCIEEKTFLLAALDEMWYYQPKTDYLGSRQFELLTTRYDAPEPQRGDAEEFVNDMLANTMLMKFCHGLKDAMVSSLADIWDDPKHDGTDCAPGTFAEYLRWGTLHLRQTRTLEPVKLTAPAGKLHHVAMFEPFPSTN
What is the function of this protein?
O-glycosyltransferase; part of the 2 gene clusters that mediate the biosynthesis of fusicoccins, diterpene glucosides that display phytohormone-like activity and function as potent activators of plasma membrane H(+)-ATPases in plants by modifying 14-3-3 proteins and cause the plant disease constriction canker (PubMed:22870285).  The first step in the pathway is performed by the fusicoccadiene synthase PaFS that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) and successively converting GGDP into fusicocca-2,10(14)-diene, a precursor for fusicoccin H (PubMed:17360612).  The second step is the oxidation at the C-8 position by the cytochrome P450 monooxygenase PaP450-2 to yield fusicocca-2,10(14)-diene-8-beta-ol (PubMed:22870285).  The cytochrome P450 monooxygenase PaP450-1 then catalyzes the hydroxylation at the C-16 position to produce fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:22870285).  The dioxygenase fc-dox then catalyzes the 16-oxydation of fusicocca-2,10(14)-diene-8-beta,16-diol to yield an aldehyde (8-beta-hydroxyfusicocca-1,10(14)-dien-16-al) (PubMed:21299202, PubMed:22870285).  The short-chain dehydrogenase/reductase fc-sdr catalyzes the reduction of the aldehyde to yield fusicocca-1,10(14)-diene-8-beta,16-diol (PubMed:21299202, PubMed:22870285).  The next step is the hydroxylation at C-9 performed by the cytochrome P450 monooxygenase PaP450-3 that leads to fusicoccin H aglycon which is glycosylated to fusicoccin H by the O-glycosyltransferase PaGT (PubMed:22870285).  Hydroxylation at C-12 by the cytochrome P450 monooxygenase PaP450-4 leads then to the production of fusicoccin Q and is followed by methylation by the O-methyltransferase PaMT to yield fusicoccin P (PubMed:22870285).  Fusicoccin P is further converted to fusicoccin J via prenylation by the O-glucose prenyltransferase PaPT (PubMed:22287087).  Cytochrome P450 monooxygenase PaP450-5 then performs hydroxylation at C-19 to yield dideacetyl-fusicoccin A which is acetylated to 3'-O-deacetyl-fusicoccin A by the O-acetyltransferase PaAT-2 (PubMed:22870285).  Finally, a another acetylation by the O-acetyltransferase PaAT-1 yields fusicoccin A (PubMed:22870285).
What are the official names of this protein?
O-glycosyltransferase PaGT, Fusicoccin A biosynthetic gene clusters protein 6.
What is the protein family that this protein belongs to?
Belongs to the afumC glycosyltransferase family.
Protein: DNAJ_MALP2
Sequence: MSSKRDYYEVLGVSKDATDDQIKSAFRKKAMQYHPDRNKEPDAEEKFKEVNQAYEVLSDPDKRANYDRFGHEGVDGQFGGGAGFDPFDIFNQFFGGGRGGGAHFEQSFGGSGFEDIFSNFFGGGRRGASSQQREANLVVSIVLTFVESVVGVKKTIEYKIEKDCESCHGSGADNSEGSISTCSNCNGSGVEITQKRTIMGIIQSQNICSRCNGEGKEIHKKCNSCKGRKVHEERVEIDVEIPGGVSNDEHLKVSGKGSVVGGKTGDLYINIQIKPSKIFSRKGNDIYVILKVDPILAIVGGEANIPTPFGIKSIKMKPGTRNGEIITVPSHGVKSTKRFGSNGDLFAVVEYTSAKRFSSAELKSLSKFAQETNDEIEKYLKEARKEIN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_CALS4
Sequence: MAFNLKGRSLLTLKEYTPQEIRYLLDIAKQVKAERKAGIVHQRFVGKTIALIFEKRSTRTRCAFETAFGEEGGHPVFLSTDDIQLGAKESIEDTARVLGRMFDAIEFRGFKQETVEILAKYAGVPVYNGLTDEYHPTQVLADLMTIEEEFGSLKGRKLVFVGDGRNNMANTLAIGCAKMGMHYVINSPKELWPSESFIKEIKDMAAENGGTFELTSVPGEGLEGADAIYTDVWASMGEEAKAEERERLLRPYQVNEEMMKKTGRDDTIFLHCLPAVKGQEVTFEVIEGKQSRVWDQAENRKHTIKAVLIATLL
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_SACD2
Sequence: MISLEDIRRDYLLGGLDLDQLDASPIAQFETWMAQAIESQIPDPTAMVLATANKDGFPSQRIVLLKKLDEQGFVFFTNYGSRKAQEIAEQSHVSLHFPWHMMERQVSVGGVASKISYAETLKYFVSRPKDSQIAAWASAQSKPISSRQLLLQQFNAIKTKFANGEVPLPDFWGGYRVVPQRMEFWQGGGARLHDRFVYEREGNSWAINRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.