PharMolix/UniProtQA huggingface dataset:
Protein: TATE_ECO57
Sequence: MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGADVDLQAEKLSHKE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatE shares overlapping functions with TatA.
What are the official names of this protein?
Probable Sec-independent protein translocase protein TatE.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family. TatE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SHE3_KLULA
Sequence: MKMTEAQEFLTPTKGVNSSKFNINHGHFITNLENQESPSKLGAYTPGKYSTSRVIESLHKQIDELTSTNLKMTSQCHQLVNELESSGKKQNKQLETISRLQTENMNLNAILDRKTNRMNELESSLKKQTVFNEDAAKKNLELEETVKKLSLENEKLTEQSTLYKIQYEAIVDAHQSYKQFFTNETSTLRNDLMSLKQSMTKQLESKTKEVLAIDEKIQNKLESLDSAQESFKKHASEQIEDNIKELRLDSWQSSLREAQALLKEYKSQAQAEGITIQEQPKASIPQLRNPKRKTSGQKRTSFYGTPTGFSIPSNKQTPPSSSSTQLPGLKRASSIRISSDPNRNR
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 3.
What is the protein family that this protein belongs to?
Belongs to the SHE3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: DNAK_MYCLE
Sequence: MARAVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSTVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGSDWSIEIDGKKYTAQEISARVLMKLKRDAEAYLGEDITDAVITTPAYFNDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGEREQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDDRIVNWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSVNLPYITVDSDKNPLFLDEQLIRAEFQRITQDLLDRTRQPFQSVVKDAGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIASHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIKIQEGSGLSKEEIDRMVKDAEAHAEEDRKRREEADVRNQAETLVYQTEKFVKEQRETENGSRVPEDTLNKVEAAVAEAKTALGGTDISAIKSAMEKLGQDSQALGQAIYEATQAASKVGGEASAPGGSNSTDDVVDAEVVDDERESK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, 70 kDa antigen, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: KNOX7_MAIZE
Sequence: ELKNELKQGYKEKLVDIREEIMRKRRAGKLPGDTASVLKAWWQAHSKWPYPTEDDKARLVQETGLQLKQINNWFINQRKRNWHSN
What are the official names of this protein?
Homeobox protein knotted-1-like 7.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HYPA_CERSK
Sequence: MHEMSLCEGIRGIVEDQARRHGFAAVKVLRLEIGRFAGVEKAALGFAFDVVMRGSAAEGARLEILDLPGRALCYDCGEEAVIEDRFDPCPLCGGGRLMPVGGDEMRIKDMEVQ
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: HNRPM_RAT
Sequence: MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPVPKGEERPTQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGSGAGGSVPGIERMGPGIDRISGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGAGGASFDRTIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA
What is the function of this protein?
Pre-mRNA binding protein, binds avidly to poly(G) and poly(U) RNA homopolymers.  Involved in splicing.  Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, M4 protein.
What are the subcellular locations of this protein?
Nucleus matrix.
Protein: SL1A_BOTJA
Sequence: DTPFECPSDWSTHRQYCYKFFQQKESWDDRSEYDAERFCSEQAKGGHLVSIESDEEADFVAQLVAPNIGKSKYYVWIGLRIENKKQQCSSKWSDYSSVSYENLVRGNVKKCFALEKKQGFRKWVNIDCVEGNPFVCKFIRPR
What is the function of this protein?
Binds to platelet GPIb (subunit alpha) (GP1BA) and functions as a receptor blocker for vWF binding to GPIb.  The platelet GPIb-binding site resides on the GPIB-BP subunit beta and not on the alpha subunit.  At a final concentration of 104 nM totally abolishes vWF-dependent shear-induced platelet aggregation (SIPA) at a high shear stress, but had no effect on SIPA at a low shear stress.
What are the official names of this protein?
Snaclec GPIB-binding protein subunit alpha, GPIb-BP subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: INTU_MOUSE
Sequence: MAGLARGDSRGRPPELPGDLSSQEEEEEEGDSDAGASSLGSYSSASSDTDVEPEWLDSVQKNGELFYLELSEDEEESLLPETQTANHVNHVRFSDKEVIIEEDDSRERKKSEPKLRRFTKILKSKSLLPRRHHKKSSSNNGPVSILKHQSSQKTGVTVQQRYKDVTVYINPRKLTAIKAREQVKLLEVLVGIIHQTKRSWKRSAKQADGERLVVHGLLPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTFENAYAVKRETAQPQKKKAQSSTQDLVKLLCGSEADAVQHSTLSIPHISMYLTLQLQSEAAREEQEILYHYPVSEASQKLKSVRGIFLTLCDMLESVTGTQVTSSSLHLNGKQIHVAYLKESDKLLLIGLPAEEVPLPQLRNMIEDVAQTLKFMYGSLDSAFCQVENAPRLDHFFSLFFERALRPGKLHLSGSPSAQQYAAASAVLLDNLPGVRWLVLPQELKVELDTALSDLEAADFEELSEDYYDMRRLYTILGSSLFYKGYMVCSHLPKDDVIEIAAYCRQHCLLPLAAKQRIGQLIIWREVFPRHHLQPPSDSDPEAFQEPEGRYFLLVVGLRHYLLCVLLEAGGCASKATGNPGPDCIYVDQVRATLHQLEGVDSRIEEQLATSPGPCLSCADWFLAAPREKADSLTTSPILSRLQGPSKTAASPTCRRTFFSDYSFKARKPSPSRIGGGREPTEGEESAGLSPHATPDAVRKQRESEGSDDNVALLKLARKKSTLPNPFHLGTSKKELSEKELEVYDIMKLTSGPENTLFHYVALETVQGIFITPTHEEVAQLGGSVHSQLIKNFHQCCLSIRAFFQQTLKEEKKKALSDGEHSEPTNSVSSLSPVKEHGVLFECSPENWTDQKKTPPVMSYWVVGRLFLNPKPQELYVCFHDSVSEIAIEMAFKLFFGLTL
What is the function of this protein?
Plays a key role in ciliogenesis and embryonic development.  Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules.  Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension.  Has an indirect effect on hedgehog signaling (PubMed:20067783, PubMed:21761479).  Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).
What are the official names of this protein?
Protein inturned, Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the inturned family.
What are the subcellular locations of this protein?
Cytoplasm. Cell surface. Cytoplasm, cytoskeleton, cilium basal body. Note=Enriched at the apical surface in ciliated cells.
Protein: RRF_RICTY
Sequence: MEKNNLKKILQEKMEKAIKVLGNELKGLRTGRASVNFLDSVTVEAYGSKVPLAQVASLSTPDARTINVQVWDKSMVSSVEKGITIANLGLTHATDGQLIRLPIPSLTEERRKEFVKLAHKYGEETKISLRNIRRDGIEELKKLEKDNIIVKDEYHSLSEQVQKLTDEYSSKVDSAIKQKEHEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTHB1_CHICK
Sequence: MGRMWASEVLLLLLLGSSRAVTPGLDVSTAPGLDGSIPPGLDGSVSPGLDGSVSPGLDGSASPGLDGSVSPGLDGSASPGLDGSTPAGRDGTITPKLEGTITPKQDGSISPSWPWRWPITYLDAILAAVRLLNQKISGPCILRLREAQPRPGWVGTLQRRREVSFLVEDGPCPPGVDCRSCEPGALQHCVGTVSIEQQPTAELRCRPLRPQPIRNWWIRIWEWLNGIRKRLRQRSPFYVRGHLNVTSTPQP
What is the function of this protein?
Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro).  May play a role in the innate immune response.
What are the official names of this protein?
Cathelicidin-B1, CATH-B1.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1161_THESM
Sequence: MIRKIKPQIRVIGFDDGTFSFKSKIKRDKTILVGVVMKGSQDVVGVVTRWIEVDGRDATEKMIEAIHNSRFKDLRIIMLKGITYAGFNVVDVEELSRETRMPVIIVIRKKPDLQAMEKALKKHFSDAEEKISLLHKAGKIKELIPGKLYYQAIGVSYDQAEEIIRLTQKSSLIPEPLRLAHMIASAVMSGESKKE
What are the official names of this protein?
UPF0215 protein TSIB_1161.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: RL24_TERTT
Sequence: MRKIKRNDEVVVITGRDKGKRGKVTRVLPDNRVIVSGIQMIKKHQKPNPQLGVAGGIVEKEAPIQVSNVAIYNPSTQKADRVGFKVLEDGNKIRVFKSDGNAIDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AIM24_EMENI
Sequence: MVQPLRRGVRPLTWTRVLPRQTRQPASSHRRAQARYVQIRATPTDQPATVNGSNVPIVDTPSSAESADARFEVIGAPYSLLSVTLSASQNLYTRRGTLVGLSGKADNVISTLSVLEPFRRAPVGVPFLYQKISSASPVTALISTRSPVTSFAVVHLNGSVDWMVAQRRALLAWTGRSLSIRPTINTSLSVAHWGSSEVTGRGLLALVGSGQLYSVELKEGEKYIVHPSNVVAYTVSSKPPRPYRFKSTSLKLQVPGLKSLPTFLQNTQFIKAMSETDSWKTAMRIFHTVRTWSRMTIWGDRLFLQFDGPSTILLQSRGARMSDVLSTQEVNEFASTPRGLTIVPTKQEEKQKGSEQDGKDDVHKAPGTRSVDEIEQEIKGVTQSIAVLTKEGKVVFQKPGQQ
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EIF3M_DANRE
Sequence: MSVPAFIDITEEDQASELRSYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKDDDKDVESVMNSIVSLLLILETEKQEALIESLCEKLVKFREGERPSLRMQLLSNLFHGMDENTPVRHTVYCSLIKVAATCNAITFMPTDLDQVRKWIVDWNLNTEKKHTLLRLVYEALVDCKKSEAAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTYLFDHLLALKPVRFLEGELIHDLLTIFVSAKLISYVKFYQSNKDFIESLGLSHEQNMSKMRLLTFMGMAVEMKEISFETMQQELQIGAEDVEAFVIDAVRTKMVYSKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLCSWKQNLSTVKSSLQTLSPTA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_COXBU
Sequence: MSLVESPPWQALKSKYQELSSLHMRDFFAQDKKRGTRLSLEAAGLYFDYSKNRVDEKTIDLLCESANACNLPLRIEQLFSGKLTNESGEMVGFHTALRQVNNFSFKTNNNAIQEIHASWEKIKKLSIRIREGDYKGFTNKSITDIVNIGIGGSSLGPQMAYNALKPYVKAPLRCHFISNLDDTDFYETVRTLNPETTLFIITSKTFTTKETLENARRATEWLMQAAKKENLIQTHFMAVTAAPEKAHEFGIQKDNIFMLWPWVGGRFSVWSAAGLSLAIAIGWEEFFEFLRGAHAMDTHFRQAEFNKNMPILLALLSIWYINFFHAKTQAIIPYSQRLVYLPDYLTQLHMESLGKSVQLDGSAVHWQTGAVVWGDLGTNSQHSFHQLFLQGTMVIPVDFIAVLKNSRESHWQLPLIANCLGQSQTLMEGYDKEGVMRDLINQGIEHEKAEKLATYRLIRGNNPSNTIILEELNPYSLGSLLALYEHKVYVQSVIWNINPFDQWGVERGKHLAKDILQALQAETDQSSFDSSTERLINYVLKIKGNRP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNR_ECOL6
Sequence: MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGMLAVKGKYITIENNDALAQLAGHTRNVA
What is the function of this protein?
Global transcription factor that controls the expression of over 100 target genes in response to anoxia.  It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism.  When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
What are the official names of this protein?
Fumarate and nitrate reduction regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VB18_VAR67
Sequence: MSRRLIYVLNINRKSTHKIQENEIYTYFSYCNIDHTSTELDFVVKNYDLNRRQPVTGYTALHCYLYNNYFTNDVLKVLLNHGVDVTIKPSSGHMPIYILLTRCCNISHNVVIDMINKDKTHLSHKDYSNLLLEYIKSRYMLLKEEDIDENIVSTLLDKGIDPNFKQDGYTALHYYYLCLAHVYKPGECRKPITIKKAKRIISLFIQHGANLNALDNCGNTPFHLYLSIEMCNNIHMTKMLLTFNPNFEICNNHGLTPILCYITSDYIQHDILVMLIHHYETNVGEMPIDERRMIVFEFIKTYSTRPLDSITYLMNRFKNIDIHTRYEGKTLLHIACEYNNTHVIDYLIRINGDINALTDNNKHAIQLIIDNKENSQYTIDCLLYILRYIVDKNVIRSLVDQLPYLPIFDIKSFEKFISYCILLDDTFYDRHVQNRDSKTYRYTFSKYISFDKYDSIITKCYEETILLKLSTVLDTTLYSVLRCHNSRKLKRYLSVLKKYNNDKSFKIYSNIMNERYLNVYYKDMYVSKVYDKLFPVFTDKKCLLTLLPSEIIYEILYMLTIYDLYNISYPPTKV
What are the official names of this protein?
Ankyrin repeat protein B18.
Protein: ZAPD_KLEP7
Sequence: MHTPVLFEHPLNEKMRTWLRIEFLIQQMAFHPQIASHADALHFFRNAGDLLDVLERGEVRTDLVKELERQQRKLQSWAEVPGVDQERINELRHQLKQSSSTLMAAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHMPQAHRDEQVASWLASLDPLVQSLSLILDLIRNSALFRKQTSLNGFYQDNGEDADLLRLRLDLAHQLYPQISGHKSRFAIRFLALDSEYGIVPERFDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: APAG_ECO27
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: E13B_WHEAT
Sequence: MPLLILLMLLAAGAAGAESATPSLHIGVNYGANADNLPSPTSVATFLATKTTIDRVKLFDANPTFISAFAGTPISLAVSLPNSALPALADKATGLDAARSWIRANLSPYVPATNVTLLLAGNEILLSTDTNLILSLLPAMRRLAQALKAEGLTGVRVTTPHYLGILAPSDGIPSNASFRAGYNTKLFPAMLQFHRDTGSPFMVNPYPYFSYRPETLNYALFRPNSGIYDPATKLNYTSMLDAQMDAIYTAMKKLGYGDVDIAVGEAGWPTQAEPGQIGVGVQEARDFNEGMIRVCSSGKGTPLMPNRTFETYLFSLFDENQKPGPIAERHFGLFNPDFTPVYDLGLLRDGASVAPTPSPNPSPNPSPKPAPSGGGKWCVAKDGANGTDLQNNINYACGFVDCKPIQSGGACFSPNSLQAHASYVMNAYYQANGHTDLACDFKGTGIVTSSDPSYGGCKYVS
What is the function of this protein?
Is thought to be an important plant defense-related product against fungal pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Beta-1,3-endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: SEN2_YEAST
Sequence: MSKGRVNQKRYKYPLPIHPVDDLPELILHNPLSWLYWAYRYYKSTNALNDKVHVDFIGDTTLHITVQDDKQMLYLWNNGFFGTGQFSRSEPTWKARTEARLGLNDTPLHNRGGTKSNTETEMTLEKVTQQRRLQRLEFKKERAKLERELLELRKKGGHIDEENILLEKQRESLRKFKLKQTEDVGIVAQQQDISESNLRDEDNNLLDENGDLLPLESLELMPVEAMFLTFALPVLDISPACLAGKLFQFDAKYKDIHSFVRSYVIYHHYRSHGWCVRSGIKFGCDYLLYKRGPPFQHAEFCVMGLDHDVSKDYTWYSSIARVVGGAKKTFVLCYVERLISEQEAIALWKSNNFTKLFNSFQVGEVLYKRWVPGRNRD
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  This subunit may anchor the endonuclease complex to the nuclear membrane.  Probably carries the active site for 5'-splice site cleavage.
What are the official names of this protein?
tRNA-splicing endonuclease subunit SEN2, Splicing endonuclease protein 2, tRNA-intron endonuclease SEN2.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
What are the subcellular locations of this protein?
Nucleus. Endomembrane system; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=The tRNA splicing endonuclease complex is predominantly associated with the outer membrane of mitochondria, suggesting that tRNA splicing mainly takes place on the mitochondrial surface.
Protein: LYSC_PHACO
Sequence: MRSLLILVLCFLPLAAPGKVYGRCELAAAMKRMGLDNYRGYSLGNWVCAAKFESNFNTGATNRNTDGSTDYGILQINSRWWCNDGRTPGSKNLCHIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRKHCKGTDVNVWIRGCRL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MT3_BOVIN
Sequence: MDPETCPCPTGGSCTCSDPCKCEGCTCASSKKSCCSCCPAECEKCAKDCVCKGGEGAEAEEKKCSCCQ
What is the function of this protein?
Binds heavy metals.  Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium.
What are the official names of this protein?
Metallothionein-3, MT-3, Growth inhibitory factor, GIF, Metallothionein-III, MT-III.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: TNFA_MARMO
Sequence: MSTESMIRDVELAEEALPKEAWGPQGSSRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREEFLNNLPLSPQAQMLTLRSSSQNMNDKPVAHVVAKNEDKEQLVWLSRRANALLANGMELIDNQLVVPANGLYLVYSQVLFKGQGCPSYVLLTHTVSRFAVSYQDKVNLLSAIKSPCPKESLEGAEFKPWYEPIYLGGVFELQKGDRLSAEVNLPSYLDFAESGQVYFGVIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: LYTM_STAAR
Sequence: MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHKHYFYNCYPKNANANGSGQTYVNQATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHNGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
What is the function of this protein?
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan.
What are the official names of this protein?
Glycyl-glycine endopeptidase LytM, Autolysin LytM.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGO_SALHS
Sequence: MISYYFQGFALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCALSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXA_GEOMG
Sequence: MPNTKPRIVITMGDPTGVGPEIIAATLAEPEVRQCCRFLVVGDSAAMARGITVAGAALRVERTDTLNWEESKEGVLPLWEISSLTEADMQYGCPTVASGDAMYRAICEAARLCLEGNADAMATAPISKEALNRAGHRYPGHTELLAELAGAERVVMMLAGFRLRVTLVTIHEALADVPRLVTFERVLETIRITHRDLHRYFRRNPRIAVLALNPHCGEGGMFGDEEARIIAPAVAAARQEGIDAIGPLSADTLFHFAVQGAYDAVVCMYHDQGLIPLKLLHFDDGVNVTLGLPIIRTSVDHGTAYDLAGTGRASAESMKAAILMAAEMARVKGSGGGTP
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNB_BACAH
Sequence: MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNEGKKVIDLDVQVYVGPARIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEFPDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHVADGDYELIALPLALSDADGSPVRAVIRPI
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: APT_CALBD
Sequence: MNLKEKFRHVLNFPKEGIDFIDITTVLQDKDAFKYAIDSLVNLVKDLDFELIVGPESRGFIFGAPVAYVLNKGLVLVRKKGKLPYKTVSVEYELEYGKDVLEMHIDAIKPGQKVVIIDDLLATGGTTLSNIKLVEKLGGEVVGIAYLVELTYLGGRENLKGYDVRSVVQFESSLI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJQ_SALTI
Sequence: MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.