PharMolix/UniProtQA huggingface dataset:
Protein: DPO3B_RICCN
Sequence: MLKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIAVQVVSEGECTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPAMDSINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSISWVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTSMLSKLIDGTFPDYSTFIPESSSSKLVINRKMFADSIERIAIITVEKFRAVKLSLSRETLEISAVGEARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDVVELYFSDVSAPVLIKFPENPKDIFVVMPVKV
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AATC2_MOUSE
Sequence: MTSLSVFRDVPTAQKLEGSLLKIYRQDGYPSKLFLAYKVCMTEEGHPWVSLVVHKTRLQIAEDPSLDYEYLPLVGLKSFIQSSLELLFGKHSEAIAEKRVGGVHIVGESGAFQLGAQFLKTWRKNVKIVCIVSCQKEQCGLIFQDMGFIVYEYSIWNASDLCSDPSMFVEVLQHIPVGSILVIGNITDCKFTQNQWTKLMSIIKSKQIFPFFDIPCQGLSTGDLEEDTKILQYFVSLGLEFFCSQSLSKNFGIYDEGVGILVVAALSNQHLLCVLSQLMDYVQALWGNPPATGARIITSILCNPALFGEWKQSLKGVVENMMLIKEKVKEKLRLLGTPGSWDHITRQSGTHGYLGLTYQQVEFLVKKKHIYLPKTSRINFTCINARNIDYITQSIHEAVMLTEG
What are the official names of this protein?
Putative aspartate aminotransferase, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Transaminase A-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRC1_DROME
Sequence: MDDTQHFCLRWNNYQSSITSAFENLRDDEAFVDVTLACEGRSIKAHRVVLSACSPYFRELLKSTPCKHPVILLQDVNFMDLHALVEFIYHGEVNVHQKSLQSFLKTAEVLRVSGLTQQQAEDTHSHLAQIQNLANSGGRTPLNTHTQSLPHPHHGSLHDDGGSSTLFSRQGAGSPPPTAVPSLPSHINNQLLKRMAMMHRSSAAAAAEETSHAFKRLRGSDNSLPLSGAVGSGSNNNSPDLPPLHARSASPQQTPADFSTIKHHNNNNTPPLKEEKRNGPTGNGNSGNGNGNGNGASNGNGISISDKLGSLTPSPLARAGADDVKSEPMDMVCSNNNANANDEHSNDSTGEHDANRSSSGDGGKGSLSSGNDEEIGDGLASHHAAPQFIMSPAENKMFHAAAFNFPNIDPSALLGLNTQLQQSGDLAVSPQGKLTTNATTTTTTINNSITNNNNNNNNNNYDYSLPTKNSNSQKTPSPTTTTLTTPTTTTPTRPTAITSASGICGLNLSTFAANGSSSGGSNGGLSMTALLPQQQQQQQQQHQMSQQQQQQQQQQQQQGNSSSGQQQQPNGILACSTPKANTPTTTQQQMYAAVMAAAASASASTSGSANSSLNNSNSTLNTSGGLNNSASGGDDFRCNPCNKNLSSLTRLKRHIQNVHMRPTKEPVCNICKRVYSSLNSLRNHKSIYHRNLKQPKQEPGVGATQAAANSFYHQQHQQQQLNHHSSS
What is the function of this protein?
Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis.
What are the official names of this protein?
Broad-complex core protein isoforms 1/2/3/4/5.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_CYAM1
Sequence: MDSFCLHHYQFSSRLILGTGRYSSPSLAQQSIEASGCEIVTVAVRRFHALHAFTPLINWNRYWLLPNTAGCRTCSEAVRVALLARQLLQHLQQPHQCLIKLEVIPDPLYLLPDPLGTLKAAEILVRKGFAVLPYIYPDPVLALQLEQIGCAAVMPLASPIGSGQGIQHVHSLQLILQNARIPVIIDAGLALPSDASRVMEMGASAVLINSAIALSPSPVSMAHAMKLAVQAGRLAFLAGRMPLSSSAHASSASFGSFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TOX4_RAT
Sequence: MEFPGGNDNYLTITGPSHPFLSGAETFHTPSLGDEEFEIPPISLDSDPSLAVSDVVAHFDDLADPSSSQDGSFSAQYGVQTLDMPVGMTHGLMEQGGGLLSGGLTMDLDHSIGTQYSANPPVTIDVPMTDMTSGLMGHSQLTTIDQSELSSQLGLSLGGGTILPPAQSPEDRLSTTPSPTNSLHEDGVDDFRRQLPAQKTVVVETGKKQKAPKKRKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQTPSPPPVTTADPASPAPASTESPALSPCIVVNSTLSSYVANQAFSGPGGQPNITKLIITKQMLPSSITMSQGGMVTVIPATVVTSRGLQLGQTSTATIQPSQQAQIATRSVLQAAAAAAASMQLPPPRLQPPPLQQMPQPPTQQQVTILQQPPPLQAMQQPPPQKVRINLQQQPPPLQSKIVPPPALKMQATVLPPTVESSPEQPMNSSPEAHTVEATSPETICEMIADVVPEVESPSQMDVELVSGSPVTLSPQPRCVRSGCENPPVISKDWDNEYCSNECVVKHCRDVFLAWVASRNPNSVVLVK
What is the function of this protein?
Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate (By similarity).  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (By similarity).  In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1.  This regulation is independent of the insulin receptor activation (By similarity).
What are the official names of this protein?
TOX high mobility group box family member 4, Epidermal Langerhans cell protein LCP1.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin.
Protein: APT_LACLM
Sequence: MELKDYIATIENYPKEGVVFRDISPLMADGNAYNYAATEIVQYARDKEIDMVVGPEARGFIIGCPVAFALGVGFAPVRKPGKLPREVIEATYEKEYGTDTLTMHSDSIKPGQRVLIVDDLLATGGTIAATIELVEKMGGVVVGCAFLIELDELKGREKIGNYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR5_LOBRE
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_SHIBS
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CJTL8_EPIJA
Sequence: MSSAIKILALLMVLVALAQAKPRKDYRAYPDFDDKSVILEDDKRCDPDKRDSVCKDVCGMLDIGTENGECPGKEVCCVDLFGR
What is the function of this protein?
In vivo, induces immediate paralysis on shrimps (C. multidentata), followed by death when high doses are injected.  No activity is observed when injected into fly larvae (M.  domestica).
What are the official names of this protein?
Toxin CjTL8.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: LPTD_ACIB2
Sequence: MVNETMKHQFKFNPLATAIFTLLCSGSIQSSYAESAGVVSNIDNNQLKASIKEAYPGQEFFQQYYVDKSAPEAQLRNNKYLSSAFCQGTWITPINPETKALDADKATSVVTADYGHYNPAGDSVLEGNVVIDQEGRTVRADKVTIDKTQTFAHAQGRVQLAQGGLLSQSDEIDYNLKTQTGNLDNSFYISEQQHAHGHAGKIERTSPNVMVLNDATYTTCPPGQKPGWKIQANKIELNQETGRGVTRGTKLYVKDVPVLAVPYFNFPIDDRRTTGILNPQFGFSNDGGIELSVPVYLNLAPNYDATITPRYLADRGAMLQGEFRYLTDGFGAGQIWGGILPSDKEYDDKDRKDFHFLHNWDINDQWSTNLEYNYASDKDYFSDLDSSPISKTDLNLRRAWELNYQHGIPGLKAQLKVEDFQTLDPEVKDVNKPYARLPQFLLNYVTGNPLGLQYEFNNDTAYFKKSINDDSAQESSGTRIYNQFATRYNYRTPAAFVIPELSVRSIQTFYDKDSIASQGLDGGSENKSVVVPQFTLDTGLNFEREGKYLQTLTPRAFYAYAPYKNQDGYPNFDSTTASISYDQLFNPYRFYGHDRLEDNNFLSLGVSYSLFDTVGLERLRASVGQSYYFEDRRVTLKQQDEIDTERNTGPVVSLSSQLNQNFTIAANSAWMSNGDNAQRDFQLYYTGDKGNLYNLGYFYRKDIPGRQDTYDQVVASFIQPIKDNWRIMGHVQYDMDNDVARELLLGVNYESCCWGISVYGRSYYNDLDDPKSPDVSEKRAIMAEITLKGLGGLNNKLASLLENRVLGFNKINQSWTQR
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: NHAB_SHEHH
Sequence: MPVTMSRAILDNFLGNSPKWFKLAIISFLVINPIVFYFNPFIAGWLLVVEFIFTLAMALKCYPLQPGGLLAIEAVAIGMTSPSQVLHEIEANLEVVLLLVFMVAGIYFMKQLLLFVFTKMITKVRSKVYVSLLFCVSSAFLSAFLDALTVIAVIITVAVGFYSIYHRVASGKSFADSHDHTSDGHPQLCEEELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFAEFAIRMSPVTVPVFFAGVTTCFLVEKFKVFGYGQQLPEAVHKILSDYDAHEDANRTKHDKVKLLVQAFIGVWLIAGLALHLASVGLIGLSVIILATAFNGITNEHALGKAFEEALPFTALLAVFFAIVAVIIDLQLFAPVIQWALSYEGNTQLVVFYIANGLLSMVSDNVFVGTVYINEVKAALLNGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSAIAPLIRLSYGRMVWMALPYTIVLSIVGVLAIQLGALEQMTQYFYDTQLLIHHSAQAVTDSVVSGH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUTC_ECO8A
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDEHADEYSRYIVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROP_DROME
Sequence: MALKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRYTPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQNYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSCLGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNYHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFLSDLGSLSKED
What is the function of this protein?
May be a component of one of the vesicle trafficking pathways.  May interact functionally with Ras2 protein.
What are the official names of this protein?
Protein ROP.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Soluble or bound to membranes.
Protein: ANM6_DANRE
Sequence: MSQHATKKRKLDRSTEDYMYFDSYSDVTIHEEMIADTVRTNTYRMGIFKNSKSIEGKVVLDVGAGTGVLSLFCAQAGARKVYAVEASSIADQAVKIVKLNQMEDRIEVIKSTLETIELAEKVDVIVSEWMGYALLHESMLNSVIFARDKWLKPGGLILPSRADLYIAPINDVVVEGRLDFWSTVKGQYGVDMSCMTDFARKCIMNKDITVNPVTVEDVLSHPCKFAELDLNTVTLEQLRDVNGSFSCVCFGSSSIHAFCVWFTVTFPAEEKALVLSTSPFKAETHWKQAVLYLDDAVDVMQDTKVEGEISLYPSEENSRHICIRVDYVIGEQKKHSKSFSIPDQYLEVK
What is the function of this protein?
Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA.  Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates.  Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a.  H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3).  Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53.  Repression of TP53 blocks cellular senescence.  Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively).  Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity.  Methylates HMGA1.  Regulates alternative splicing events.  Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1.
What are the official names of this protein?
Protein arginine N-methyltransferase 6, Histone-arginine N-methyltransferase PRMT6.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YUBL1_ECOLI
Sequence: MRMSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLVVRNNGAMVWRTWNFEDGAGYWMNHVIRDFGILK
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: HEMH_ZYMMO
Sequence: MTESNNPLPISEKIGVLLVNLGTPDAPNAKALRRYLGQFLSDQRVIELPAVFWQIILRGIILPFRAPRSARAYQKIWTNEGSPLAAITKKQAQGLQKRMPNITVDYAMRYGTPSISSRLEKLIASGCRRILLAPLYPQYSAASTATVQDEAYRYLQKIRWQPNLRSLEPYYTHPAYIQTLKKNIEDQIKALDFKPDSLLLSYHGMPVKTRELGDPYYFQCQATSQALSSLLDIPVITSFQSRFGSQKWFTPATDMTLKELPSKNIRNLAVAMPGFSADCLETLEEIALQGKSTFLEAGGENFAALRCLNDSEESLAMLEILVNQGLSGWLKSGE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESV1_ORYSI
Sequence: MAACSRGLVARPFDLTARGAAHWPCPAPRRRAIRCCCRAQQEPRRRLSKAAAAAPERTEEWRIDGNKPAAAARGRRRASLTAMPSLPFPSPRSRRQWKQQNFYPRCTPRGPAPQSRDTPPKRDTGIASEKEWGINLLDEAVKESGTNEDGSTWYRESGDDRGDNGYRCRWARMGGQSHDGTTEWKETWWEKSDWTGYKELGAEKSGKNGAGDSWWEKWKEVLYQDEWSNLARIERSAEKQAKSGAENAGWYEKWWEKYDAKGWTEKGAHKYGRLNEQSWWERWGEHYDGRGFVLKWTDKWAETDLGTKWGDKWEEKFFAGIGSRQGETWHVSPGGDRWSRTWGEEHFGNGKVHKYGKSTTGESWDLVVDEETYYEAEPHYGWADVVGDSTQLLSIQPVERPPGVYPTIDFSASSPAPPSDDPPGMPPSPLE
What is the function of this protein?
Binds preferentially to highly ordered alpha-glucans, such as starch and crystalline maltodextrins (By similarity).  Involved in the organization of the starch granule matrix, thus influencing starch turnover by modulating the accessibility of starch polymers to modifying and degrading enzymes (By similarity).  Required for the control of starch degradation in leaves and starch distribution in nonphotosynthetic parts (By similarity).  Promotes gravitropic responses, negative in shoots but positive in roots, by facilitating starch granules (statoliths) formation in hypocotyls and roots columella (By similarity).  Facilitates tight packing of starch granules in grains (By similarity).
What are the official names of this protein?
Protein EARLY STARVATION 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ESV1 family.
Protein: MEND_PELPB
Sequence: MNNRQINSLWSSIIIEELIRQGADFFCISPGSRSTPLTVAIARNPKARWKMFADERSAAFFALGYGRATARPAVLICTSGTAVANYFPAIVEASMDFQPILVLSADRPFELLECGANQTIRQENIFGSYTRWHMQLPVPSKEIPLKALLSTIAHAVVKTIGSPAGPVHLNQPFREPLEPEIPDLKDAWAAPLQEWLENGKPSGKSALPEKEPDAETLSLLREALAVAKEPLIIAGNMQKPEEAEAVEQLALELQIPLYTDFSSGLRLKSTTRPWQLAFASPHFTRHFKPDLVLHFGGHIIAKQPAAAIREWKPKHYIVVKNHANRLSPDHNVTLSIEASIASTAAKLKGCRTLSSGIINAATEEFFRRAEEEIDAECIGNKPVTEISAARLVSRLITAQQRLFLSNSMPVRDMDNFACSSHPHAIRSAINRGASGIDGIISTAAGFAEGDGKSTTLIIGDIAFLHDLNALSLLGAMTVPLQIIVLNNNGGGIFSFLPIAEYRDLMETHFATPQNYSIRSAAETFGLDYACPQTNQEFTRCYLEATGSPRSIIIELRSNRAENLHHHRALQARIETLTNHLYQGFIEKISEQPN
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: PROA_BRUME
Sequence: MTKDIAQVMAEVGRKAKAAAAPLSIATNEQKNKALNAAADAILEARADILEANRLDLANAEKNGMAASFVDRLTLNEARIDAIAEGIRAIATLPDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSAHSSAAIYKALVKGLEAANLPADAIQIVPVTDRAAVGEMLKGLGGAIDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGICGAAETLLVDRAVASTHLAPILGDLAAGGCEIRGSAEVLALYPAAKPATEEDWSTEYLDAIISVALVDGISGAIDHINRYSSHHTEAIVAEDAQTVARFFNEIDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCMT1_NEUCR
Sequence: MSGSAPSIPNLLTLRGRIGGGGVTRGRYRGVIHRGGRGHGPGAPSASAAHDATIQGTDTDAAVSRLSAVQIGYIDDPYAELFAQSGPGAARRLPIINRGTYARTTAIDKLVDKFLDDTESSPEGRQIVSLGAGTDTRSLRLFSPSAPTPRKRVIYHEIDFPAMCEKKQRIVCSAPQLRSILSDPDSVEELSQHGGGNSWHSKAVAEKHKGSELWVHGLDLRAIAASQQPQQPLPPGVPIGSRGLHASPFTPGSTTQHEEQTEETSLPQQREPLTLTSLNPNLPTLIISECCLCYLPPSTASSIVSFFTTTIQSSLSIVIYEPIKPDDAFGKMMVSNLAAREIRMPTLEVYKEAEDQERRLREAGFSGGEGKGIGGARSKTIEQIWEEWTSQEEKERVDALEGLDEVEEWKLLAGHYIVVWGWRGVGVDLEI
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, Protein phosphatase methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: ATPD_ALIB4
Sequence: MKDLVAKRYVKALIDGRNSESINTISNKLNQVASAFADERFNSIISSPEISDKSKVDLIISFVDGTDNSLNNFIKLLGEKRRLDLLPFIAKDLNIQLAKMNNNYIGVVYTNQELSSDYISSIEKQFSKKFDVKLSLSQNVCDYDGIKVDIDGLGVEISFSKDRLKSQLIDHILKAV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PILY1_PSEAB
Sequence: MIHQITRAGKSLLAAGCTLSILFASDSYAATALNVSQQPLFLTQGVAPNLLFTLDDSGSMAWAYVPDGISGNSGRAGRSSDYNALYYNPDYAYQVPKKLTLSGDQIIVSDYPVPRFTAAWQDGYAQGSTTNLSNNYRPQWGTGWLGCIDSSCNTGRAYYYTYKVSASCPAQPVSSSNSCYTYNALPTSQESNFAIWYSYYRNRILATKTAANLAFYSLPENVRLTWGALNTCSIGANSRSCQNNALLQFNKQHKINFFNWLANSPASGGTPLHAALDRAGRFLQTNGTAYTTEDGKTYSCRASYHIMMTDGIWNGRNVTPGNLDNQNQTFPDSTLYRPQPPYADSNASSLADLAFKYWTTDLRPSIDNDLKPFMAYKSGDDSKDYWDPRNNPATWQHMVNFTVGLGLSYSLTLNSAPTWTGSTFGNYEELMAGSKAWPSVDNDAAPGNVYDLWHAAINSRGDFFSAESPDSLVQAFNKILTRISERNTSSSKPAMTSALQDDGTGDKLIRYSYQSSFASDKNWAGDLIRYKVESTSTGSTKTQEWSAGALLDNRAPATRNIYIASNSGTNRLKPFTWSNIEGSQLATWLNRNPDKDNQADTKGAQRVDFIRGQQNMDGFRQRQAVLGDIVHSSPAVVGPAQYLTYLANPIEPSGDYGTFKTEADQRSPRVYVGSNDGMLHGFNIKTGVEEFAFIPTAVFEKLNKLTGISYQGGAHQYFVDATPVVSDAFFDGAWHTVLIGTLGAGGRGLFALDVTKPDDVKLLWEYDSSTDSDLGYTFSKPTVARLHSGQWAVVTGNGYGSDNDKAALLLIDLKKGTLIKKLEVQSERGIANGLSTPRLADNNSDGIADYAYAGDLQGNIWRFDLIGNTRNDDPDTNTSINPFKPGDVDPSAFRVSFSGAPLFRARADNNTRQPITAPPTLVRHPSRKGYIVIVGTGKYFEDDDAQADTSRAMTLYGIWDRQTKGESANSTPTIDRNALTAQTMTTEANSTFGSVNRNIRLISQNPVKWYKDGATGTANSDVASYGWRLNLEVNSSKKGEMMIEDMFAAGQVLLLQTLTPNDDPCDSGSTSWTYGLNPYTGGRTSFTVFDLKRAGIVDSGSDYNGSVVSAFQQDGLGGLAITQNEQRQSEACTGDECIIFNPSDKSNGRQTWRVVEEK
What is the function of this protein?
Involved in pilus assembly, twitching motility and adhesion to host cells.  Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili.  Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT.  Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).  Regulates surface-activated virulence possibly by acting as a surface-attachment mechanosensor (PubMed:25385640).
What are the official names of this protein?
Type IV pilus biogenesis factor PilY1, Pilus-associated adhesin PilY1.
What is the protein family that this protein belongs to?
Belongs to the PilY1 family.
What are the subcellular locations of this protein?
Fimbrium. Membrane. Cytoplasm, cytosol. Note=Colocalizes with the T4P fraction when surface pili are present. Sheared surface fraction when PilV, PilW and PilX are also present.
Protein: FPG_ACTSZ
Sequence: MPELPEVETAKNGITPYLDGFYIEKIIVRQPKLRWEVSPELSQISHQKVTALSRRAKYLIIHTAQGYIIGHLGMSGAVRIVSPDSPVNKHDHLDIVMNNGKIMRYNDPRRFGAWFWTENLDEFPLFAKLGPEPLSGEFNSDYLFKKSRKKPTAVKSFIMNNAVVVGIGNIYANEVLFQCGLHPEKPAGKITKTQAALLTETIKKELTRAIAQGGTTLKDFLQPDGKPGYFVQELQIYGKKGCPCPKCGQKIESFTVGQRNSYVCLHCQKK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LIPA_BACC3
Sequence: MTKQTEYKRKPEWLKIKLNTNENYTGLKKMMRSKNLHTVCEEAKCPNIHECWAVRKTATFMILGAVCTRACRFCAVKTGLPTELDLQEPERVADSVVQMGLKHVVITAVARDDLKDGGAAVFAETVRAVRRKNPFTSIEVLPSDMGGVEENLKMLMDAKPDILNHNIETVRRLSDRVRARAKYDRSLEFLRRAKEMQPDIPTKSSIMVGLGETREDLIEAMDDLRANNVDILTLGQYLQPSKKHLPVLKYYPPAEFAELKEIALSKGFSHCEAGPLVRSSYHADEQVRSAKEKTAEAK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOAH_SALDC
Sequence: MFAGLPSLSHEQQQKAVERIQELMSQGMSSGEAIAQVAGELRANHTGERIVARFEDEDE
What are the official names of this protein?
UPF0181 protein YoaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.