PharMolix/UniProtQA huggingface dataset:
Protein: COMD1_CANLF
Sequence: MAAELEGSKALGGLLSGLAQEAFHGHHGITEELLRSQLYPEVSLEEFRPFLAKMRGILKSIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKNHKTKIRESLMNQSRWDSGLRGLSWRVDGKSQSRHSAQIHTPVAIMELEIGKSGQESEFLCLEFDEVKVSQLLKKLSEVEESISTLMQPA
What is the function of this protein?
Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins.  Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2.  Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation.  Down-regulates NF-kappa-B activity.  Involved in the regulation of membrane expression and ubiquitination of SLC12A2.  Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L.  Promotes the localization of SCNN1D to recycling endosomes.  Promotes CFTR cell surface expression through regulation of its ubiquitination.  Down-regulates SOD1 activity by interfering with its homodimerization.  Plays a role in copper ion homeostasis.  Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.  Can bind one copper ion per monomer.  May function to facilitate biliary copper excretion within hepatocytes.  Binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.  Negatively regulates neuroblastoma G1/S phase cell cycle progression and cell proliferation by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a FAM107A- and actin-dependent manner.
What are the official names of this protein?
COMM domain-containing protein 1, Protein Murr1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome membrane. Cytoplasmic vesicle. Early endosome. Recycling endosome. Note=Shuttles between nucleus and cytosol. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins (By similarity).
Protein: TRUA_IDILO
Sequence: MRMALCLEYDGSRYYGWQRQREVASVQQCVEEALSKIANAPVEVTCAGRTDAGVHATAQIVHFDVPVPRADVAWTLGVNSNLPAGIAVRWAREVDSEFSARFSATSRRYRYIIANTRFRPGIHSAGVSHYHQPLDAEVMQEAAQALVGEHDFTAFRASHCQSHTPFRKVSDLTVERRGDYIIVDISANAFLHHMVRNIVGSLIVVGQHLQPPDWIGELLRQKDRTKAAATAKPGGLYLVAVTYPEHYNIPDAPLGPLWLGD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RS16_HELPY
Sequence: MTVIRLTRIGRKKKPFYRVVVTDSRKRRDGGWIESIGYYNPLSEPKDIKIDKERLNYWKGVGAKMSERVEKLSQKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: B2_NODAM
Sequence: MTNMSCAYELIKSLPAKLEQLAQETQATIQTLMIADPNVNKDLRAFCEFLTVQHQRAYRATNSLLIKPRVAAALRGEELDLGEADVAARVRQLKQQLAELEMEIKPGHQQVAQVSGRRKAAAAAPVAQLGRVGVVNE
What is the function of this protein?
Binds double-strand RNA (dsRNA) with high affinity.  Suppresses the host RNA silencing-based antiviral response.
What are the official names of this protein?
Protein B2.
What is the protein family that this protein belongs to?
Belongs to the nodaviridae B2 protein family.
Protein: RL16_ESCF3
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CEP41_RAT
Sequence: MSDSPIDGSPQPEPDYRYKKDELFKRIKVTTFAQLVIQVASLSDQTLEVTAEEIQRLEDSDSATSEADTDIAAKTNGKGSPEEQSPSPVQFINSTGAGDASRSTLQSVISGVGELDVDKGLVKKEEPSGKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLVTGSLPASCQQALPFGSVRKRPGPKMPALPAENKWRFTPEDLKKIECYLEADQGPANNPSRLNQNNSAGRDLKVPAGRGGQNLPTGCPTSHSNSRTLNSGHLQGKPWK
What is the function of this protein?
Required during ciliogenesis for tubulin glutamylation in cilium.  Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium (By similarity).
What are the official names of this protein?
Centrosomal protein of 41 kDa, Cep41, Testis-specific gene A14 protein.
What is the protein family that this protein belongs to?
Belongs to the CEP41 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes mainly to the cilium basal body and in primary cilia.
Protein: SPRTL_STRP7
Sequence: MKLTDYVKQVSLEDFCRPFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_RUMCH
Sequence: MDKDLLISNIKKMKKEQNAVIVAHSYQVDEVQEIADVTGDSLALSQFCASSQADTIVFCGVHFMAESAKLLSPEKTVLLPEINAGCPMADMVTAEALKEAKKKYPHAAVVCYINSSAEVKAECDICCTSSNAEKVIRSIDKKDIIFAPDKNLGSYVAKKVPEKNIIFWEGYCITHHKIKKDAVIESKRLHPDAILLVHPECRPEIQELADFVGSTKQIIDYARNSEHDKFIIGTEMGVLYQLKKENPNKTFYMMSTGLICPNMKKTSLQSVHDALAKRQYEITLDSGIIERASGSLNRMLAVGK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_MARMS
Sequence: MTTILTVRKGNQVVVGGDGQVSLGNTVMKGNARKVRRLYRGEVIAGFAGGTADAFTLFERFEGQLEKHQGHLVRAAVDLAKDWRSDRALRKLEAMLIVANKESTLIITGTGDVVEPQHGALAIGSGGNFAEAAARALIDNTDLTAKEIVEKSLNIAADICVFTNHSLTIEEITIDAQLEDKSK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOB1_METTH
Sequence: MHIDNVVFMKKVLDASAFINGYVPEGRENYTVRSVTEEIRDFRSMMILEDALREGRLKITEPDPESMKVVEDAISESGDIMRLSPTDMEVIGLAVSLRGKDDVTVITDDYTIQNTLKILGIGFRSVLTSGIRDTYSWRRVCTGCRRVYPLDYEFEECEICGSRIVRKRHRN
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity).
What are the official names of this protein?
Endoribonuclease Nob1, RNase Nob1, Endonuclease VapC2, Putative toxin VapC2.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: TRI33_DANRE
Sequence: MEVEASGTEDNGDGGAKEPEAVVSIDTETKEAADEAKSQETVPQTPTTSSDSSSSGGGGEATDGTPNAESADPPPPPPPPPPPPPSTPADSTAAAASPAVLTEMSPPPPASTSSSSSTPAAPINLLDTCAVCKQSLQNRDCEPKLLPCLHSFCLKCIPQPDRKITMPVQGPHGQDTRIVNVMRCTVCHQDYKQIDMVDNYFVKDTSEATNTSVENSTQVCTSCEDNASAIGFCVECGEWLCKTCIEAHQRVKFTKDHKIRKKEEVSPESVGTSGQRPVFCPVHKQEALKLFCETCDTLTCRDCQLLEHKEHRYQFLDEACQNQKGIIATFMTKLQEKRGLVEYSASEVQKRLKEVAETHKKVEHEIKIAVFTLINEINKKGKSLLQQLESVTKDRSMKLLSQQRDISVLAQQIIHVLNFTNWAITNGSSTALLYSKRLITYQLRLIMKARVDAVPPANGAVRFFCDPTFWAKNVVNLGNLVIEKVAPTAPPSNMMVNQQISPGHNHPGKHSGQINLAQLRLQHMQQAAIAQKHQQQHQHHQQQQHQHQHQQQQQQQQQQQQQQQQQQQQQQHQQQIQQQMRIASQMSQHPRQGAPQMIQQPPPRLISMQALHRGGVNGSSHMFPPHHLRMVSAQNRMPSAQPRLNGQPYPMMQPQLQRQHSNPGHAGPFPVASLHNISAANPTSPTSASMANAHMHRGPSSPVITPIELIPSVTNPENLPCLPDIPPIQLEDAGSSTLDNILSRYISANAYPTVGPTNPSPGPSTHSPGSSGLSNSHTPARPSSTSSTGSRGSSGTTVDQVKVKQEPGVEEECSYSGANVKTERTKDGRRSACMMSSPEGSLTPPLPILGSVSTGSVQDILRTLGENVKSEPQSDNLSSCTNPNSRATLTNGTSGSNGGQRGGATNANSQTTAGKEDDPNEDWCAVCQNGGELLCCDHCPKVFHITCHIPTLKSSPSGDWMCTFCRNLANPEIEYNCDDDPPRNKEKNEMAMSPEEQRRCERLLLHVFCHELSTEFQEPVPTSVPNYYKIIKHPMDLTLVKRKLQRKHPLHYKSPKEFVSDVRLVFSNCAKYNEMSRIIQVYDEEKQSNVQADSEVAEAGKAVSLYFEERLLEIFPEQTFPVVMEKETQIEAEKEDSDDSDDDIIQPKRKRLKVDTEMLLHIK
What is the function of this protein?
May act as an E3 ubiquitin-protein ligase and a transcriptional repressor (By similarity).  Involved in the regulation of embryonic and adult hematopoiesis.  Required for normal development and survival of both committed erythroid progenitor cells and posterior mesenchymal cells.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, Protein moonshine, RING-type E3 ubiquitin transferase TRIM33, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARND_ERWT9
Sequence: MIDVGLRIDVDTWRGTRDGVPNLLSILQRQQTRGSFFFSVGPDNMGRHLWRLLKPRFLWKMLRSNAASLYGWDILLAGTAWPGRRIGQGQAEVIRATARQHEIGLHAWDHFAWQTWAGVWPAERLSAEIRRGVEALADIVGQPVDCSAVAGWRADGQVVAAKQPFDFTYNSDCRGVRPFRPQLPDGSLGTVQIPVTLPTWDEVIGSSVTREGYNDFILDQITQHQGVPVYTIHAEVEGIVLSEMFERLLVEAGRRGIRFCPLGELLPQDVTQLPVGKIVRGHNPGREGWLGCQQLS
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: CSN6B_ARATH
Sequence: MAPSSSSGLTFKLHPLVMLNISDHFTRVKTQLNPPAASCATGNGSNNADAMLLQNPRVYGCVIGLQRGRTVEIFNSFELIFDPALDTLDRSFLEKKQELYKKVFPDFYVLGWYSTGSDATESDMHIHKALMDINESPVYVLLNPAINHAQKDLPVTIYESEFHVIDGIPQSIFVHTSYTIETVEAERISVDHVAHLKPSDGGSAATQLAAHLTGIHSAIKMLNSRIRVLYQHIVAMQKGDKPCENSVLRQVSSLLRSLPAAESEKFNENFLMEYNDKLLMSYLAMITNCTSNMNEVVDKFNTAYDKHSRRGGRTAFM
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes.  The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex.  Essential for the structural integrity of the CSN holocomplex (PubMed:17307927).
What are the official names of this protein?
COP9 signalosome complex subunit 6b, AtCSN6b, Signalosome subunit 6b.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EIF3G_DEBHA
Sequence: MSASVIKSWADAEDEIPTPEITTNPDGTKTVVSYRLNANGQKVKITQKIKEVKVKEKVHPLIAQRKNWAKYGKEKNTPPGPDTRTTQLGEKVELKLGTSWKEIEKQEEESKEEQKAQLVSTQRIKCRTCGGDHFTSKCPFKDTLISDSTDASNAATPEPADDGMNAPGKYVPRHLRKDANGNMPAKDLKDRDDSTTLKISQLNSIVDEDMLRNELLGRYGPFQRAIVVRNRETGESRGFAYVTFATESKAEEALNDLNGKGYHSLILHLEWSKKRK
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3378_BACAC
Sequence: MQNKIQVKSVEKRENALIFCAENSEIEVKGLSARNHVLVDSDNLSFLYILENESSFIYVSIPHTCWEAMNNDVVMFVRVNDIEMELEGLKEEVEYLVENIEGNANYGEELVTAVEKVFL
What are the official names of this protein?
UPF0738 protein BAMEG_3378.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: TGNB_ACIAD
Sequence: MRFSLFVHMERVSDQQTQKQLYDEMIELCQIADRGGMHAIWTGEHHAMNFTIAPNPFLNIADLANKTKHVRLGTGTVVAPFWHPIKLAGEAAMTDIISNGRLDIGIARGAYSFEYERMVPGMDAWSAGQRLREMIPAIKNLWKGDYEHNGEFWQFPKTTSAPQPLQQPNPPIWVAARDPNSHEFAVQNGCNVQVTPLHLGDEEVEKLMGHFNSACEKFQDIERPEIMLLRHTYVADSEEDAQVAANEMNVFYNYFGAWFKNEREINQGLIAPLSDEEIAAHPFYTPEAMRKNNVIGQAQEVIDRLKAYEAMGYDEYSFWIDTGMSFERKKASLERMINEVMPAFSESKVDRRHATISAVY
What is the function of this protein?
Involved in the degradation of the pyridine ring of trigonelline (TG; N-methylnicotinate) into succinate and methylamine as carbon and nitrogen sources, respectively.  Catalyzes the insertion of two oxygens, followed by a ring cleavage of trigonelline to yield (Z)-2-((N-methylformamido)methylene)-5-hydroxybutyrolactone (MFMB).  It is able to use reduced FMN or FAD.
What are the official names of this protein?
Flavin-dependent trigonelline monooxygenase, oxygenase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: ATPF2_RHOPB
Sequence: MAEGHGDANGATAHTAADGGHKAPFPPFQKDTFASQLVSLLIAFVALYLIVSKIALPRVGSVLDERAKRIEDDFAAAQRLKGESDDALKAYETELAQARARAQAIGAETRERLNAASEAERKSLEEKLAVKLAEAEKTIAATRETAMSNVRGIAADAAAAIVQQLSGLVPDGKALDRAVDATLKGSQA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RUVC_DESHD
Sequence: MLILGIDPGTAIMGYGLIEKKGNRLFPVDYACWRTPAHTPMPERLLMLYHEIEAYIKEKQPHHVAVEELFFNRNTTTAISVGQARGVVLLAAAQCGLPVYEYTPLQVKQAVAGYGRADKQQIQQMVRALLGLQEIPKPDDTADALAIAICHAHSVNLLNRMGGAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HIS4_BRUO2
Sequence: MILFPAIDLKDGQCVRLKLGDMDQATIYNEDPAAQAKAFEDQGFEWLHVVDLNGAFAGESVNGTAVEAILKATKNPVQLGGGIRTLAHIENWLSRGLRRVILGTVAVRDPALVMEACKAFPGQVAVGIDAKGGKVAVEGWAEASRLGVIELAKKFEGAGVAAIIYTDIDRDGVLAGINWDSTLALAEAVSIPVIASGGLASMEDIRRLATPEMRKLEGAISGRALYDGRIDPAEALSVLRAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM34_KLULA
Sequence: MSLRKVRSLPSLRVLAEVSNPLVRVPPPSFTYQTRQVHNTKKNEHSPMLSSDSHASFTRMSLKTLKNECRTRGLKVSGKKTELVERILLFEGSSSKKLHTSAIQRAKNDSSHIDSMKIPNVAKLEAEAESRKTDYIVKVPSIVNNAATEPKTKIEKDYEKKLQPADKKPLAENVGTVATPDADNVIQTPSVSDSIKVVNPEEELRSGSSEQGRSYSQQDEELTSRDKKFLLGFAGTVAAWWSLRFWKKEESKK
What are the official names of this protein?
Altered inheritance of mitochondria protein 34, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM34 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: VF421_ASFWA
Sequence: MYTHVDVVGIAEASAALYVQKDRDRYSDVLTTIENFIYQHKCIITGESAHLLFLKKNIYLYEFYSNNVAEHSKALATLLYKLDPEYLTRYTVLITKIPNHWYVINVDQREFVRLYAIPAVKQHLPIPILPFYCTSALTQQELFCLGPELQLIQIYSKLCNPNFVEEWPTLLDYEKSMRTLFLEQFPQRLEMTGGKKEEEEKHESIIKKIILEMVSTRQRIVVGGYIQKNLYNHVLKNRNRLQLITSLNIYEEKDIIQQFCDSNGLKIKIRINNPLLPTNPELRRLTIYFNNTNDDDQSYLIVDMYNTGSYELVPTNQINTLDGSFLIGTPFVQARFLLVEIWVLMLIAQQTKKDTKKIIQFFINQYEMLMNSPWPSMEALFPSSSKRYLGNYVDPNALIKWAQLKLKRIPPFYPGKPDEKSC
What are the official names of this protein?
Uncharacterized protein K421R, pK421R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus K421R family.
What are the subcellular locations of this protein?
Virion.
Protein: PH4H_CHLRE
Sequence: MLALRQGALLLSARGGQTTHDNLQLCAGPSRRPRARWISSAPRPSTLVERHIRPQASTASDATTSTSQRILSIHDVDNGQILGFGADLAEDHPGFHDPAYKQRRAWLAEMAKTHRIGTPIPDVEYSPAEVATWDAVLEELSGLLPQHACREYLRCLTLFDFRKGRVPQLEEMNTVLRSTTGWTVRPVAGLMHPRHFLAGLAFKHFHSTQYMRHPSKPSYTPEPDVVHELIGHVPLLADPAYARLIQTIGLASLAADDKQIWHLTKVYWHTVEFGVVREGDQVKAFGAGILSSYGELAHMASGAAALERLDPFRPQPRMAYKDGFQKRYFVLDSFAEGSELLSSYAASLGLPESLRGDASVA
What is the function of this protein?
Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine (Probable).  Can functionally complement an Escherichia coli tyrosine auxotroph (PubMed:20959559).
What are the official names of this protein?
Phenylalanine 4-monooxygenase, chloroplastic, Aromatic amino acid hydroxylase, Phenylalanine 4-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: Y2684_MYCTO
Sequence: MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFYSHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMILLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNIGGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLFGSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHIQPSLVALLGAGMLIAVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTGVVNDLARAATQLTGGNIVATAFLILGVSAPISGIIDNIPYVATMTPLVAELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAPISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
What are the official names of this protein?
Uncharacterized transporter MT2758.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADR_SALPC
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANSEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_CANAL
Sequence: MVEFYFHDNKDTLENFTEDHNSGEPVSFDQLAEIGVIYKYITTQEELDALATEREYKNRDVVTLNLPAFNNDIDAYNAKMQQFYKEHYHEDEEIRYIAEGEGYFDVRDKQDRWIRAKLSPYDLLILPAGIYHRFTLTNAAKHVKAVRLFKDEPKWEAINRDTGKNTEARELYAKTIAV
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PGDH_RAT
Sequence: MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP
What is the function of this protein?
Catalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites (PubMed:9099857) (By similarity).  Decreases the levels of the pro-proliferative prostaglandins such as prostaglandin E2 (whose activity is increased in cancer because of an increase in the expression of cyclooxygenase 2) and generates oxo-fatty acid products that can profoundly influence cell function by abrogating pro-inflammatory cytokine expression.  Converts resolvins E1, D1 and D2 to their oxo products, which represents a mode of resolvin inactivation.  Resolvin E1 plays important roles during the resolution phase of acute inflammation, while resolvins D1 and D2 have a unique role in obesity-induced adipose inflammation (By similarity).
What are the official names of this protein?
15-hydroxyprostaglandin dehydrogenase [NAD(+)], 15-PGDH, Eicosanoid/docosanoid dehydrogenase [NAD(+)], Prostaglandin dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHI1L_DANRE
Sequence: MKLYAKLLLCSICVAFIAVRWSAPSFNEESLKGARVLVTGASTGIGEQLAYHYARLGAQIVITARRGNVLEQVVSKCREMGAQKAFYIPADMANPSDADLVVKYAIEQLGGLDYLVLNHIGPSPYQMWDGDVQHTRWLLEVNFLSYLQMAQKALPTLEKSKGSIVVVSSLLGKICGPFALPYASTKFALNGFFGGLQNELAMQKSNVSITICILGLIDTDSAMEKIKGYINMTAYPSHEAALQIIQAGATRQSESFYPWYTFYATLFRDWFPYLRDKVIQNSYTYNP
What are the official names of this protein?
Hydroxysteroid 11-beta-dehydrogenase 1-like protein, 11-beta-hydroxysteroid dehydrogenase type 3, 11-DH3, 11-beta-HSD3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_SYNS9
Sequence: MAVPKKKTSKAKRNQRSATWKGKAAIAAKRAMSIGKSVLSGRAQGFVYPVSDTDEAEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.