PharMolix/UniProtQA huggingface dataset:
Protein: GRHL1_MOUSE
Sequence: MTQEYDNKRPVLVLQNEALYPQRRSYTSEDEAWKSFLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRERRSSAVKPEGEHPEPEHSKRNSIPNVTEQPLISAGENRVQVLKNVPFNIVLPHSNQLGIDKRGHLTAPDTTVTVSIATMPTHSIKTEIQPHGFAVGIPPAVYHSEPTERVVVFDRSLSTDQFSSGTQPPNAQRRTPDSTFSETFKEGVQEVFFPSELSLRMPGMNSEDYVFDNVSGNNFEYTLEASKSLRQKQGDSTMTYLNKGQFYPVTLKEGSSNEGIHHPISKVRSVIMVVFAEDKSREDQLRHWKYWHSRQHTAKQRCIDIADYKESFNTISNIEEIAYNAISFTWDINDEAKVFISVNCLSTDFSSQKGVKGLPLNIQIDTYSYNNRSNKPVHRAYCQIKVFCDKGAERKIRDEERKQSKRKVSDVKVQLLPSHKRTDITVFKPFLDLDTQPVLFIPDVHFTNLQRGSHVLSLPSEELEGEGSVLKRGPFGTEDDFGVPPPAKLTRTEEPKRVLLYVRKESEEVFDALMLKTPSLKGLMEAISDKYDVPHDKIGKIFKKCKKGILVNMDDNIVKHYSNEDTFQLQIEEAGGSYKLTLTEI
What is the function of this protein?
Transcription factor involved in epithelial development.  Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' (PubMed:18288204, PubMed:21081122).  Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier (PubMed:18288204, PubMed:24586629).  There is no genetic interaction with GRHL3, nor functional cooperativity due to diverse target gene selectivity during epithelia development (PubMed:21081122).  May play a role in regulating glucose homeostasis and insulin signaling.
What are the official names of this protein?
Grainyhead-like protein 1 homolog, Transcription factor CP2-like 2, Transcription factor LBP-32.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. Grainyhead subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COXX_HYPNA
Sequence: MTELTAATPTKRPATATDYVNLMKPRIMMLVVFTAVAGLAAASGMTGITMHPAMAAIAVLAVALGSGAAGAINMWYDADIDAIMSRTSTRPIPSGAVPKEEALTMGLIMSGVSVMLMWLASNWLAAALLAFSIFYYGVIYTMWLKRATPQNIVIGGGAGAFPPVIGWAAVTGNTPLDAWILFAIIFFWTPPHFWALSLLAHKEYAKVSVPMLPVTHGAKATRFQILVYTLVLIPVSLAPLATGLGGWIYGAVAGGLGLVFLAYAVAILRSKAGDDGAPAGDMKLARTAFLFSILYLFALFGAVLVEHAAGLHFPVFGA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFPL_SALCH
Sequence: MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLVLELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSAGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: AROK_BURTA
Sequence: MQARDPHVNVIFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGARIPVIFELEGESGFRDREAQMIAELTQRENIVLATGGGAILRPENRKLLHERGLVVYLRANPHDLWLRTRKDKNRPLLQTDDPKAKLEALYEARDPLYRECAHFVIETGRPSVNGLVNMVLMQLEMAGIVAKPLQA
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKB1A_MOUSE
Sequence: MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLIISSDYAYGATGHPGIIPPHATLVFDVELLKLE
What is the function of this protein?
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand.  Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal.  May modulate the RYR1 calcium channel activity.  PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TMM86_DICDI
Sequence: MEEPIIIDNNNIESLSQQQHSTVTNIDSNAGNVLYIDKDMWWKLLYTMFITTGIGYLMAKRNSTSKFRIIKPIPVVILGYIVLLWCSIHHKSGTQQMFNLIIPNNPTTYAMYISVGLFLSAVGDFFLLYKRFFIHGVFFFLVAHISFIFAFTSSEQFFTPTVTALLVGIVCLFVYMYLAKVFPLFSKMGISKSLAIALLFYTSVIVTMCFTASVKSFLKLITIINNNHDIFSNIFSSFSFYASIGAIGAVLFFISDLMILVREINQLANGQVSTIRKLLGHGDLGMIVYWLGQFCIALSVTEF
What are the official names of this protein?
Lysoplasmalogenase homolog, Transmembrane protein 86 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM86 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FPG_BORPA
Sequence: MPELPEVETTRRGIDTVITGRTLRRLVVREARMRWPIPPALPDLLAGRTVLECGRRGKYLLLRFDHGVQIVHLGMSGSLRRVPEQEAPRKHGHVDWVFDHAVLRLHDPRRFGAVLWHPDEAGPIAAHPLLARLGIEPFDPRFDGRWLHAYFRGRRVAIKQALLAGDAVVGVGNIYASESLFRAGIDPRTAAQRVSAARCDRLAAAIRATLSDALDSGGSTLRDYVGASGEPGAYFAIHAAVYERAGLPCRVCGAPIRRLVQGQRATYFCPSCQKR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS3_COXBU
Sequence: MGQKVNPVGMRIGITRDWTSNWYADKKDFADRLNEDLNVRQLLQKRLKGAAVSRIQIERPARNAKIIIHSARPGVIIGKKGGEIEALRDEIFKVMKVPVHITIEEVRKPELDAKLVAENIAQQLERRVMFRRAMKRAVQNTLRQGALGVKISVSGRLGGAEIARTEWYREGRVPLHTFRADIDYATASAKTTYGIIGVKVWIFKGEVHAPKPQAEEAAPQETEEEVK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SCXE_BUTOM
Sequence: VRDAYIAQNYNCVYACARDAYCNDLCTKNGARSGLFATFGPHGDACWCIALPNNVPLKVQGKCHRK
What is the function of this protein?
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin Boma6e, Alpha-neurotoxin Bom alpha-6e.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_STRTD
Sequence: MKSITQLENKKVLVLGLAKSGEAAARLLAKLGAIVTVNDGKAFEENPSAQSLLEEGIKVVCGGHPLELLDENFELMVKNPGIRYDNPMVARALEKEIPVWTEVELAYLVSEAPIIGITGSNGKTTTTTMIADVLNHGGKSGVLSGNIGFPASEVAQSVTNQDTLVMELSSFQLMGIESFHPHIAVITNLMPTHIDYHGSFEEYVAAKWNIQNEMTSDDFIILNFNQDLAKELATQTNAQVVPFSTVEKVDGAYLENGGLYFKGELLMHADELGVPGSHNVENALATIAVAKLSGVSNQAIKETLSSFGGVKHRLQFVDTIDDVKFYNDSKSTNILATQKALSGFDNSKVILIAGGLDRGNEFDELIPDITGLKKMVILGESAPRVKRAADKTGVTYLDAKDVADATRIAFEQASAGDVVLLSPANASWDMYKNFEVRGDEFITTVERLKG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTY13_HUMAN
Sequence: MKTQDDGVLPPYDVNQLLGWDLNLSLFLGLCLMLLLAGSCLPSPGITGLSHGSNREDR
What are the official names of this protein?
Putative transcript Y 13 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYS_ANAPZ
Sequence: MHDIEFIKNNPELFDKAMLSRGLESQAAKIIELDLQKRKLLTELYALREQRNAITKEVTVLKQSGADCSSHVETSKKLAHEISELEERIKRDTGLSYLLCSLPNIPDDAVPFGKSADDNVEVRSYGQKRSFSFEIKPHYVLGEMLNLMDFRRAAFLSGSRFSILSGQLAALERGLASFMLEMHTKEFGYTEVFHPSLVNDLAMFNVGQLPKFTHDSFQTTDAMRLVPTSEVVLTNLVANTNLHRNSLPLRFTAYSQCFRSEAGSAGQDTRGMIRQHQFSKVELVSITDASQSNVELERMLSVAEEVLKRLELPYRVVLLCTGDMGFSASISYDIEVWMPAQNKYREISSCSNCKDFQARRMGAKCFYLEKQNKRSSFVHTLNGSALALGRTIAAIMENYQNSDGTITIPDALRKFMSADYIRPGTALP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC_PONPY
Sequence: MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSPRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSLPKSCTSPDSSAFSPSSDSLLSSTESSPQASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHIKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDAEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSIQAEEQKLISEKDLLRKRREQLKHKLEQLRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: FLOT1_ORYSJ
Sequence: MGFAYRIASASEYLAITGYGIADVKLAKKAWVAPGQRCTRFDISPVNYTFEVQAMSAEKLPFILPAVFTIGPRADDDDCLLRYAKLISPHDKLSHHVNELVKGVIEGETRVLAASMTMEEIFQGTKSFKQAVFENVQLELNQFGLIIYNANVKQLVDVAGHEYFSYLGQKTQQEAVNQAKVDVAEARMKGEVGAKERDGMTRQNAAKVDAETKVYTVKRQGEGAKEEARVKAEVKVFENEREAEVAEANADLAMKKAGWQRQAMVAEVEAAKAVAIREAELQVEVERTNASRQTEKLKAEHLSKAVVDYEMKVQEANWELYNRQKAAEALLYEQEKQAEARRASADAAFFARQREAEAELYAKQKEAEGLVAMGDAQSAYLSAMLGALGGSYAALRDYLMVSSGVYQEMARINADAIRGLEPKISVWSNGAGAGGEVGEGGGAMKEVAGVYKMLPPLLTTVHEQTGMLPPAWMGTLTGGAPSSTS
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-like protein 1, Nodulin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane, caveola.
Protein: AROQ_CORGL
Sequence: MPGKILLLNGPNLNMLGKREPDIYGHDTLEDVVALATAEAAKHGLEVEALQSNHEGELIDALHNARGTHIGCVINPGGLTHTSVALLDAVKASELPTVEVHISNPHAREEFRHHSYISLAAVSVIAGAGIQGYRFAVDILANLKK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CPFC_LEUMM
Sequence: MNKKGLLLVNLGTPDSPHPDDVKAYLKEFLSDTNVIQMPRLLWQPILRGKILPKRSFKSAELYQKIWRKDGSPLMVYAKKQVEQVQQLQPNWIVRCAMTYRKPNIAETLKEMRLAGADDIVVLPLFPQYSVTSTQSVIDQVRKADKNINIVKSFYNDEAYLDLLARDIREAWAKNDYDRLIISYHGVPESYVRRGDPYVDHCTATTQGVLERVGPLTPDNTHQVFQSRFGPTEWVKPYLSDTLRSLPSQGIKRVLVATPAFVADCLETIEEIHVENHDIFKQAGGEVFDVVQPFNEHIDFSKYIASLANRHFAQN
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHB_ECO57
Sequence: MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILKPLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQ
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: SUI1_ASHGO
Sequence: MSIENLKSFDPFADTGDDEASSSNYIHIRIQQRNGRKTLTTVQGIPEEYDLKRILKVLRKDFGCNGNMVKDDEMGEIIQLQGDQRAKVCEFLITQLAIPKKNIKIHGF
What is the function of this protein?
Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.
What are the official names of this protein?
Protein translation factor SUI1.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: SHD_MOUSE
Sequence: MAKWLRDYLNLGSRRPPPQPPTPDYTESDILRAYREQKDLDFEDPYEDSNGRAEPEVTGSGDPKYNSPRHRLIKVEAADMARAKALLGSPGEEPEAETEYSDPFDAQPQPPAPNSGYMEPYDARSVSSEQPSRAVQLYDTPYEEQATKPEDGGSSGQSRRPLEDERPADEYDQPWEWKKDHISRAFAVQFDGPDWERTPCSTKEPWRPQPAERVDTALALEKQPWFHGPLSRAEAENLLSLCKEGSYLVRLSETRAQDCILSLRSNQGSMHLKFARTRENQVVLGQHSGPFPSIPELVLHYSARPLPVQGAEHLALLYPVTSSQSSQGPCTLAAKPERGQGDP
What is the function of this protein?
May function as an adapter protein.
What are the official names of this protein?
SH2 domain-containing adapter protein D.
Protein: CAPSD_BPPGK
Sequence: MTIEKNLSDVQQKYADQFQEDVVKSFQTGYGITPDTQIDAGALRREILDDQITMLTWTNEDLIFYRDISRRPAQSTVVKYDQYLRHGNVGHSRFVKEIGVAPVSDPNIRQKTVSMKYVSDTKNMSIASGLVNNIADPSQILTEDAIAVVAKTIEWASFYGDASLTSEVEGEGLEFDGLAKLIDKNNVINAKGNQLTEKHLNEAAVRIGKGFGTATDAYMPIGVHADFVNSILGRQMQLMQDNSGNVNTGYSVNGFYSSRGFIKLHGSTVMENELILDESLQPLPNAPQPAKVTATVETKQKGAFENEEDRAGLSYKVVVNSDDAQSAPSEEVTATVSNVDDGVKLSINVNAMYQQQPQFVSIYRQGKETGMYFLIKRVPVKDAQEDGTIVFVDKNETLPETADVFVGEMSPQVVHLFELLPMMKLPLAQINASITFAVLWYGALALRAPKKWARIKNVRYIAV
What is the function of this protein?
Assembles to form an icosahedral capsid.
What are the official names of this protein?
Major capsid protein, Major head protein.
What are the subcellular locations of this protein?
Virion.
Protein: SERC_HAES1
Sequence: MQVFNFSAGPAMMPKVVLEQAQQELLNWLDQGTSVMEVSHRGKYFMEMITQAEKDFRQLYNIPENYKVLFLQGGARGQFAAIPMNLANKKGKTLYLTSGHWSATAAKEARLFTEVDEINILLDGKLEVGELDFSHIASQYDYVHYCPNETISGVEIVDVPNVGEAVLVADMSSNILSREIDISKFGVIYAGAQKNLGPAGITVVIVREDLIGHARKETPSIWNYEIQSKNSSMINTPPTFAWYLCSLVFKYLLAQGGIKEMAKLNREKAKLLYDFLDQSDFYHNVVAPKNRSLMNVTFTTNNDELNAKFVAEATACGLQALKGHKVLGGMRASIYNAMPIEGIKALIEFMRKFEAENN
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN1_USTMA
Sequence: MAFKLNIGLLALSLSLSLVHLDGVRAGMATRYWDCCLASASWEGKAPVYAPVDACKADGVTLIDSKKDPSGQSGCNGGNKFMCSCMQPFDDETDPTLAFGFGAFTTGQESDTDCACFYAEFEHDAQGKAMKRNKLIFQVTNVGGDVQSQNFDFQIPGGGLGAFPKGCPAQWGVEASLWGDQYGGVKSATECSKLPKPLQEGCKWRFSEWGDNPVLKGSPKRVKCPKSLIDRSGCQRKDDNTISPYSGKVDSANTAAPAQYKRDRSVCLAGGKKGKSAAGGVDGSGDASGGADASGAGGAAEGSQGQPEGYGQPSGGNDQGSSNGDATTGAGSGSGSDSGSTANGSGSGAPTSGSDGSAVAPPSGGSNPGAAQGGQGGAQPGPSGGHKKCHKKH
What are the official names of this protein?
Endoglucanase 1, Cellulase 1, Endo-1,4-beta-glucanase 1, EG 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 45 (cellulase K) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FRDD_MYCTU
Sequence: MTPSTSDARSRRRSAEPFLWLLFSAGGMVTALVAPVLLLLFGLAFPLGWLDAPDHGHLLAMVRNPITKLVVLVLVVLALFHAAHRFRFVLDHGLQLGRFDRVIALWCYGMAVLGSATAGWMLLTM
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYDND_NITWN
Sequence: MHRYRSHTCGALRDSHIDQTVRLSGWCHRIRDHGGVLFIDLRDHYGLTQCVADPDSPAFALAEKLRSEWVVRIDGKARRRPAGTENPELPTGDVEIYVTEIEVLGPAAELPLPVFGEQEYPEDIRLKYRFLDLRRENLHQNIMTRGAIVDSMRKRMKEQGFFEFQTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMMSGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVEQDDVFAAVEPVITGVFEEFAKGKPVTRNWPRIPFAESLRKYGTDKPDLRNPLLMQDVSEHFRGSGFKVFARMLEDSKNQVWAIPGPGGGSRAFCDRMNSWAQGEGQPGLGYIMWREGGEGAGPLANNIGPERTEAIRVQLGLKAGDAAFFVAGDPAKFWKFAGLARTRLGEELNLIDKDRFELAWIVDFPMYEYNEEDKKVDFSHNPFSMPQGGLDALNTQDPLTIKAFQYDITCNGYEIASGGIRNHRPEAMVKAFEIAGYGENDVVERFGGMYRAFQYGAPPHGGMAAGVDRIVMLLCGTNNLREISLFPMNQRAEDLLMGAPSEVAPKQLRELHIRLNLPQN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YISB_BACSU
Sequence: MAKQIAGICELCGRSDVQLTEHHLTPKEEGGTFLPTAMLCIPCHKQIHALYTNQELAVRLNGMAELRSDPELARFVKWIRKQPPEKLIKTKKSNERKKKK
What are the official names of this protein?
Uncharacterized protein YisB.
Protein: CHS2_ASPNG
Sequence: EIGFTRTLHGVMQNITHLCSRSKSRTWGKDGWKKIVVCIIADGRKKVHPRTLNALAALGVYQEGIAKNVVNQKQVNAHVYEYTTQVSLDPDLKFKGAEKGIMPCQVLFCLKEHNKKKLNSHRWFFNAFGRALQPNICILLDVGTKPAPTALYHLWKAFDQNSNVAGAAGEIKAGKGKGMLGLLNPLVAS
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 2, Chitin-UDP acetyl-glucosaminyl transferase 2, Class-II chitin synthase 2.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_BRUME
Sequence: MSVSDPLGDMLTRIRNAVGRKKTKVSTPASKLRARVLDVLQAEGYIRGYTQSEFENGKAEIEIELKYYEGVPVIREITRVSKPGRRVYVSVKSIPQVVNGLGISILSTPKGVMADHEAREQNVGGELLCRIF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TWST1_CEBCA
Sequence: MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGSAGGGGGGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
What is the function of this protein?
Acts as a transcriptional regulator.  Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction.  This interaction probably involves the basic domains of both proteins.  Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B.  Regulates cranial suture patterning and fusion.  Activates transcription as a heterodimer with E proteins.  Regulates gene expression differentially, depending on dimer composition.  Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression.  Heterodimerization is also required for osteoblast differentiation.  Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Twist-related protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RT18B_PANTR
Sequence: MAASVLNTVLRRLPMLSLFRGSHRVQVPLQTLCTKAPSEEDSLSSVPISPYKDEPWKYLESEEYQERYGSRPVWADYRRNHKGGVPPQRTRKTCIRRNKVVGNPCPICRDHKLHVDFRNVKLLEQFVCAHTGIIFHAPYTGVCVKQHKRLTQAIQKARDHGLLIYHIPQVEPRDLDFSTSHGAVSATPPAPTLVSGDPWYPWYNWKQPPERELSRLRRLYQGHLREESGPPPESMPKMPPRTPAEASSTGQTGPQSAL
What are the official names of this protein?
28S ribosomal protein S18b, mitochondrial, MRP-S18-b, Mrps18-b, S18mt-b, 28S ribosomal protein S18-2, mitochondrial, MRP-S18-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YBEY_SACD2
Sequence: MLTIDIQQASTADASQLPSDKQFEIWVEAALQQRMNEAELSIRIVDEDESQALNLQYRGKDKSTNVLSFPCELPDGVELPLLGDLVICAQVVAKEALEQGKLLHAHWAHMVVHGTLHLLGYDHIEDGEAEEMEAIEIQVLLELGYPNPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSOB_ECOLX
Sequence: MRKLFLSLLMIPFVAKANFMIYPISKEIKGGSSELIRIYSKSKDTQYIKVYTKKVLNPGTKEEYEVDTPNWEGGLVTTPSKVILPGGGSKSVRLSQLKDISSEDVYRVYFESIKPEKQDGLSKNKSLKTDLSVNIIYAALIRVLPKDGKSDMRASLSPKSSLLIKNTGNVRVGIKDAFFCKKTSINNDDCIKKTYNKNIYPGSSFDTGVIQNGFSHIFIDSVDGSAGKQGKRMLISIH
What is the function of this protein?
Might function as a shuttle protein in the transport of fimbria through the periplasmic space or might function as an adhesin.
What are the official names of this protein?
CS1 fimbrial subunit B.
What are the subcellular locations of this protein?
Fimbrium.