PharMolix/UniProtQA huggingface dataset:
Protein: FIS_SALAR
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: PURT_PROMH
Sequence: MTILGTALTTNATKVMLLGAGELGKEVIIECQRLGIETIAVDRYANAPAMHVAHRHYVVNMLDSEALKQIITQEKPDFLVPEIEAIATSLLVELENNGQKVVPCARAVKLTMDREGIRRLAAETLHLLTSPYQFVDDEAAFRKAAVEIGFPCIVKPVMSSSGKGQSVIRSEQDLTSAWTYSQEGGRAGQGRVIVEKMIPFDFEITLLTIRAIDGIHFCEPIGHRQEKGDYRASWQPQKMSDIALAKAQHIASKVVENLGGYGLFGVELFIQGDEVFFNEVSPRPHDTGLVTLISQDLSEFALHVRAFLGYPIGGIRQLGACASAVILPELSSTNIVYTGLEKALKANRQIRLFAKPEIAGHRRLGVVLAHADSIKHAIEEANLGAQAILAHDGDNHLSR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SYE_PROA2
Sequence: MQTTLGPRVRTRFAPSPTGYLHVGGLRTALYNYLYAKKVGGDFIVRIEDTDQARKVEGADQSLLKTLEESGIVADESILHGGNFGPYMQSERLDTYAQYCRQLLDQNNAYYCFSTAEELDENRKLQMKQGIQPKYNRKWLPETMGGNMPQSEIQKKLDEGAPYVIRMKVPDYISIMFEDIVRGPVEFDSATVDDQVLMKSDGFPTYHFASVIDDHLMEITHIIRGEEWLSSMPKHLLLYEFFGWEAPRFAHLPLLLNPDRSKLSKRQGDVAVEDFIAKGYSPDAILNFVALLGWNEGEGSEQEIYSLEELVQKFSLERVGKAGAVFNIDKLDWIEKQYIKARPVDQIIQAIKPLLQKELAEKSTDMDVARISSDEYLTQVIDLMRERVNFENEFITFSNYFYFDPETYDEAAVAKRWQDDTNEVLAEFITELEESDDFSADNIEAMLKAFVAPKGKKPAFLIHPLRILSSGVGFGPSLYHMLEVLGKQTVIRRLKKGIERVTV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_METVS
Sequence: MKVLLIGGGAREHAIAMALKKNRSVELYTLMKNKNPGIYGLSKEVSFNNETDIDKIKEFAEKIRPELAIIGPEAPLGVGAADLLTEMGIPTVGPKKLPAQIETSKEFMRNLFKKYNIKGSLKYAAFNEYGENLEKFIDEMTGLGKDVVVKPAGLTGGKGVKVVGEQLKNNDDAKLYAKEVFEKSIGGGKIIVEEKLVGVEFTLHGFVDGENIVFMPAVQDHPHAYNNDEGPITGGMGSYSCSNHKLPFLPDDKLDEAKEIMKETVNAIKAEVGPYNGFLYGQFMLTKDGPKIIEYNARFGDPEAMNLLPILKTDFLDVCFGISNGNLDNINIEFENKATVCKYVVPNGYPICPVKNKEILVNSNEIEKAGAILFYASVNEENGKLVITGSRSAAVTGISERIEDAEKIAQDAIINFEGEIFFRSDIGTKKLIEKRIERMKELI
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: ACCA_NEIG1
Sequence: MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQISQVSRHPQRPYTLDYIDALFTDFEELHGDRHFADDHAIVGGLARFNGQSVVVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDTPGAYPGIGAEERGQSEAIGKNLYELTRLRVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEKAADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSZ_SULIA
Sequence: MIVVKIGGRVVKNSLDKVILDIANINDKVILVHGGGDIVTDYTKRLGIEPVFVTSPEGIRSRYTTKEELEVYIMAMSLINKTITSKLCSLGKNAIGITGVDGGLLLAERKKRIIVIDERGKKRIIEGGYTGKVKEVRSEVINHLMKLFDIIVVSPLALDVEESTPLNIDGDQAAFAISKAVKVNVLVILSDVEGVLVEGKVVDRLTPEEAKELSKKIGPGMNRKLLMAAESVENGVNKVIIGSGVKDRPVSSALELNGTVIVNG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
[LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYF1_DICDI
Sequence: MPSINENEDIINKLKMSTITDDIIIQPSIDDLPYEEDVSKNPYSVNCWLRYLEFKQGSPQKQRNYIYERAIRELPRSYKIWHQYLLERTLAIRGKCILENSFEAVNTLFERSLVFLDKMPRIWIEYCEFLMIQEKITLTRKTFDRALIALPVTQHYRIWNEYTKFILKRSIPSLTCIRVYKRYLKIQPEKVEEYIEYLIKIKEWQEVVNQLIKLLDNVKFKSIKGKSRHDHWLQLCEILSSYPKQITGVDVDSVIRSGIGKFSDQIGKLWCYLSDYYIQLAQFEKARDIFEEALTSVGTARDFSFIWESYTQFEDSLIAAKQEILEEDPSEDNLLEFDIIIERYENLIQRQPLLLNSVMLKQNPNNVQEWLKRVNLYSNPTPNVKMIIQTFTDSIKSIDPQLAKGKLSTIYSTFAHFYEQNNKLSQARLIFENSLTVNFKTIDDLSTLYCDYAEMELKHRNYEKAIEILKRGTVSPKKQNTIIEENEPVQKRLFKSIKIWTFYVDLEESFGTFHNTKSIYEKMIQLKVVTPQIILNFAKYLEENKYFEDMFKAYEHGVQLFLFPHVQDIWITYLTKFIQRYAGMKLERTRDLFEQVLSKVPPKESIIFYLMYANFEEQYGLARHSMAVYDRAAKSVDKEDRFKMYLLYIHRASEFFGVNQTREIFSKAIEQLPDQYVRDMCLKFADMEKKYGEIDRARSIYIHGSQFSDPRTSMFYWNTWSDFEKLHGNEDTFKEMLRIRRSVQASYITQNPTLALLNKLNNKDDKDDKNQQQKQQQQQQEKQQQQQQQQQQASTLTKSKPVTVSLPETIQYNKKIENDDEINLDDDEEEEEEEDQLAIKAFPKTLLKII
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1, Protein XAB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus. Note=Detected in the splicing complex carrying pre-mRNA.
Protein: NU1C_ORYNI
Sequence: MIIDRVQVEAINSFSNLELLKEVYGLIWILPILTLLLGITIEVLVIVWLEREISASIQQRIGPEYAGPLGLLQAIADGTKLLFKEDILPSRGDIPLFSIGPSIAVISILLSFLVIPLGYRFVLADLSIGVFLWIAISSIAPIGLLMAGYSSNNKYSFLGGLRAAAQSISYEIPLTFCVLAISLLSNSLSTVDIVEAQSKYGFFGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKYGLFYLVSYLNLLVSSLFVTVLYLGGWNLSIPYISFFGFFQMNKMVGILEMTMSIFITLTKAYLFLFISITIRWTLPRMRMDQLLNLGWKFLLPISLGNLLLTTSFQLVSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YRDF_BACSU
Sequence: MRKIIIDGRDFENIEVLHDDLKDKLDFPDYYGRNLDALWDCLTGWVDLPLTLVLKNFEFSNTFLGSYADDVLEVIQEAQEELKDEFKIIIE
What are the official names of this protein?
Putative ribonuclease inhibitor YrdF.
What is the protein family that this protein belongs to?
Belongs to the barstar family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_ECODH
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: COE2A_XENLA
Sequence: MFGVQETLGRAGTALRDKALGVGMDPIRSWVRNVGVVDAKVAAQSGVAVSRAHFEKQPPPNLRKSNFFHFVLALYDRQGQPIEIERTAFVDFVENEKEFSTEKTNNGTHYKLQLLYSNGVRTEQDFYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVVPRHPGDPERLAKEMLLKRAADLVESLYGAPHNNQDIILKRAADIAEALYSVPRNHNQIPTLSSSPVHSGMMGINSYGGQLGISISESQANSQGYIRNTSSISPRGYSSSSTPQQSNYSTPSNSMNGYSNVPMSNLGVPGSPGFINGSPTTSPYGIMPSSPPVGSSGSSSILPFSSTVFPSIKQKSAFAPVIRPQGSPSPACSSSNSNGFRAMTGLVVPPM
What is the function of this protein?
May play a pivotal role in the transcriptional cascade that specifies primary neurons in embryos.  Stabilizes the higher neural potential of selected progenitor cells that express neurog2/X-ngnr-1 by maintaining Delta-Notch signaling.  Thus ensures the transition between neural competence and irreversible commitment to a neural fate.  Also promotes neuronal differentiation by activating neurod1 expression, directly or indirectly (By similarity).
What are the official names of this protein?
Transcription factor coe2-A, Xcoe-2, Xcoe2, Early B-cell factor 2-A, EBF-2-A, Xebf-2-A.
What is the protein family that this protein belongs to?
Belongs to the COE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPH_CUPNH
Sequence: MRPSGRAADALRSISLTRHYTRHAEGSVLCAFGDTKVLCTASVLAKVPPHKKGSGEGWVTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRAMRSVFDLAALGEYTVHLDCDVLQADGGTRTAAITGAFVAAHDAVSTMLRDGLIAASPIRDHVAAVSVGMVDGVPVLDLDYAEDSSCDTDMNVVMTGSGGFVEVQGTAEGAPFSRADLDAMTRLAEAGIARLVQHQREALGLA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PURT_HAHCH
Sequence: MVRIGTPLTDVATRAMLLGSGELGKEVAIELQRFGVEVIAVDRYSNAPAMQVAHRAHVIDMLDPKQLRALIELERPDFIIPEIEAIATAELLELERSGFNVVPSARAANLTMNREGIRRLAAEELGLSTSPYAFAADFESFRDAVSSIGVPCVVKPIMSSSGKGQSVIHSDGDVERAWRYAQEGGRAGQGKVIVEGFVDFDYEVTLLTLRHAGGTSFCDPIGHLQVDGDYRVSWQPHPMSAIALGAAQDIAEKVTVALGGCGIFGVELFVKGDEVYFSEVSPRPHDTGLVTLVSQNLSEFALHARALLGLPVPLIKQTGASASVALLVEGDSSRVCFSSLEAALCHPEVQLRLFGKPEVHGKRRMGVVLAQSENLDEARKLAQKAVDSIVVELGPDIKQE
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: GLMM_XANP2
Sequence: MSRRYFGTDGVRGRANATLTADLALRVGMAAGLIFQRGEYRHRVVIGKDTRLSGYMIENALVAGFTSVGMDVLLLGPVPTPAVGMLTRSMRADLGVMISASHNPFDDNGIKLFGPDGFKLSDEVEREIEELIDEDIAKRLAKPAEIGRAKRLEGVHARYIEYAKRTLPRDQTFDGIRVVVDCANGAGYKVAPEALWELGADVVSIGVEPDGMNINRDVGSTSPAALSAKVREVRADIGIALDGDADRVIIVDEKGHVVDGDQLMAVVAESFKEDGRLARSGLVATVMSNLGLERHLAGEGISLARTAVGDRYVLERMRADGYNVGGEQSGHIILSDYSTTGDGLVAALQVLAVVARRGKPVSEVCHRFDPLPQILKNVRYASGRPLEDEKVKIVIADAERRLANHGRLLIRPSGTEPVIRVMGEGDDRDLVENVVDDVIDVLQKVAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MRD1_SCHPO
Sequence: MSRIIIKNIPRYYDKEKLSTYLKSLPQLDAEITDVSVAKTKEGVSRRFAFIGFKNEEDADKAIRYLNKSYVETSRIEVHRALDYRSANEKLRPYSKYASKNIELKLQKKEKEEELRNLEEEKAKKKKDANLKRKFLDTLDPKAREFLKLSSSISNSRSWENEEVFDTEITNPVIPADEDDDEYQDLPAAKRHEGDSIKSTEHDSTLDSGVVIDGREKSSSELHEEESEQAAEGDTAKNSGTDAQAPLSDDEWLRLHRTRIKEKQPEEEVSVVGDELKSFDKENNDEHLERVTNDKIADASMLQKAENNVSEQERNIQLISETKRLFLRNLTYSCAEDDLKSLFGPFGQLEQVHMPIDKKTNNPKGFAYIDFHDADDAVRAYLELDAKPFQGRLLHVLPAKARSSILLDDYALSKLPLKKQRELKRKNTAASSTFSWNSLYMNADAVVTSLASRLGVKKTDILDPTSSDSAVKQALTETHVIQETKNFFEEHGVDLDAFKNAARSDNVLLVKNFPYGTSAEELTSLFSPFGELGRILIPPAGTIAIIEFLNAPDCRQAFSKLAYTRIKSSILYLEKAPRDVFTTSFKQSGKPELAQKVNAVEATTSEKVGTEDIESLDTATIYVKNLNFSTKQEEFQKVFKPLEGYLSAVIRAKPDPKRPGKYLSMGFGFVEFKDKASAVAAMHAMNGFVLDGHKLEIKLSHQGVDAAAEVRKQDSSKPKGTKILIKNLPFEATKKDVQSLLGAYGQLRSVRVPKKFDRSARGFAFAEFVTAREAANAMRALKNTHLLGRHLVLQYASNATMDDMQHAIEKMAKEANAEAAAPSITGKRLIETD
What is the function of this protein?
Involved in pre-rRNA processing.
What are the official names of this protein?
Multiple RNA-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_ACTPJ
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYISESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL37_SCHMA
Sequence: MTKGTTSFGKRHNKSHTQCRRCGRKSYHIQKKTCSSCGYPSARLRKYNWSEKAKRRRTTGTGRMLHLKRVHRRFKQGFRSGPPKPVKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
60S ribosomal protein L37.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: FADI_SHESR
Sequence: MSDRQQVTNAKGERIAIVAGLRTPFAKQATAFHGVSALDMGKMVVNELLARSELDPKLIEQLVYGQVVQMPAAPNIAREIVLGTGMDVSTDAYSVTRACATSFQSAVNVAESIMTGNIEIGIAGGADSSSVLPIGVSKKLAHALVDLNKARSFGQKLQIFRRLGIKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHTLASETWASGHLRDEVMVAHVPPYKQFIERDNNIRENSDLSSYAKLRPAFDKKHGSVTAANSTPLTDGASAIILMSEGRAKALGYQPIGYIKSYAFTAIDVWQDMLMGPSYATPLALKRAGMELEDLTLIEMHEAFAAQTLANMQMFASKKFAEEKLGRNRAIGEIDMSKFNVLGGSLAYGHPFAATGTRLITQVCRELKRRGGGTGLATACAAGGLGAAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEPA_PAENI
Sequence: MQTRYGRRALTIWPLLLLAIAAEVAATSLLPQTNGFRKLKPTVAVACLYTVAFALLAQILKFTDIGIAYALWAGLGTASVAVIGVLFRNERFSWKHAIGLALVVTGVVTLNLQAGQ
What is the function of this protein?
Component of an efflux pump responsible for the transport of nicotine breakdown products, in particular methylamine, out of the cell.  This pump apparently serves as a metabolic valve for nicotine catabolites and may protect the bacteria from the potentially toxic side effects of these compounds.
What are the official names of this protein?
Nicotine metabolites export pump subunit NepA, SMR efflux pump subunit NepA.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. NepA/NepB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALBUB_XENLA
Sequence: MKWITLICLLISSSFIESRILFKRDTDADHHKHIADVYTALTERTFKGLTLAIVSQNLQKCSLEELSKLVNEINDFAKSCINDKTPECEKPVGTLFFDKLCADPAVGVNYEWSKECCAKQDPERAQCFKAHRDHEHTSIKPEPEETCKLLKEHPDDLLSAFIHEEARNHPDLYPPAVLALTKQYHKLAEHCCEEEDKEKCFSEKMKQLMKQSHSIEDKQHHFCWILDNFPEKVLKALNLARVSHRYPKAEFKLAHNFTEEVTHFIKDCCHDDMFECMTERLELTEHTCQHKDELSSKLEKCCNIPLLERTYCIVTLENDDVPAELSQPITEFTEDPHVCEKYAENNEVFLGRYLHAVSRKHQELSEQFLLQSAKEYESLLNKCCKTDNPPECYKDGADRFMNEAKERFAYLKQNCDILHEHGEYLFENELLIRYTKKMPQVSDETLIGIAHQMADIGEHCCAVPENQRMPCAEGDLTILIGKMCERQKKTFINNHVAHCCTDSYSGMRSCFTALGPDEDYVPPPVTDDTFHFDDKICTANDKEKQHIKQKFLVKLIKVSPKLEKNHIDECSAEFLKMVQKCCTADEHQPCFDTEKPVLIEHCQKLHP
What is the function of this protein?
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.
What are the official names of this protein?
Albumin B, 74 kDa serum albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEFB8_MOUSE
Sequence: MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK
What is the function of this protein?
A synthetic peptide displays antimicrobial activities against S. aureus, P. aeruginosa, E. coli and B. cepacia.  The antimicrobial activity against S. aureus, E. coli and B. cepacia is reduced in raised concentration of NaCl, but its action against P. aeruginosa is independent of NaCl concentration.
What are the official names of this protein?
Beta-defensin 8, BD-8, mBD-8, Defensin, beta 8, Defensin-related peptide, Defr1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PACA_LITCT
Sequence: MFTLKKSLLLLFFLGTISLSLCEQERDADGDEGEVEEVKRGFLDIIKDTGKEFAVKILNNLKCKLAGGCPP
What is the function of this protein?
Antibacterial peptide with amphipathic alpha-helical structure that exhibits potent broad-spectrum activity against Gram-positive and -negative bacteria (Ref. 1, PubMed:34789753).  It is active against Listeria ATCC 54004 (MIC=30 ug/ml), S. aureus ATCC 25923 (MIC=7. 8 ug/ml), S. suis 2 CVCC 606 (MIC=31. 25 ug/ml), B. subtilis ADB403 (30 ug/ml), K. pneumoniae ATCC 700603 (MIC=60 ug/ml) and P.  aeruginosa ATCC 227853 (MIC=30 ug/ml) (Ref. 1).  Does not show activity against Salmonella ATCC 20020 and the fungus Candida albicans (Ref. 1).  Is also cytotoxic to HeLa cells at high concentrations (Ref. 1).  In addition, shows a strong antitumor activity but only a little hemolytic activity (Ref. 1).  Despite the presence of a Gly residue at position 10, this alpha-helical peptide remains relatively rigid, not exhibiting any significant flexibility during the molecular dynamics simulation (PubMed:34789753).  The peptide shows a preference for a position parallel to the target membrane that suggests it exerts its antimicrobial activity through a non-pore-forming mechanism of action, such as the carpet model or the interfacial activity model (PubMed:34789753).
What are the official names of this protein?
Palustrin-Ca, Host defense peptide, HDP.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: ILVD_CROS5
Sequence: MSENLRSRAVTQGSQRTPNRAMLRAVGFGDDDFNKPIVGVANGFSTITPCNMGINDLAKRAEAGIKSAGGMPQMFGTITISDGISMGTEGMKYSLVSRDVIADSIETACNGQSMDGVIAIGGCDKNMPGAMIAMARMNIPAIFVYGGTIKPGHYNGEDLTVVSAFEAVGQHSAGKIDDNTLLAIERNACPGAGSCGGMFTANTMSSAFEVMGMSLPYSSTMAAEDAEKADSTEKSAFVLVNAIRNQILPRQILTRKAFENAVSVIMAVGGSTNAVLHLLAIANTIGVDLTLDDFETIRQRVPVLCDLKPSGRYVTVNLHQAGGIPQVMKMLLNHGLLHGDALTISGQTIAEILADVPDEPPANQDVIRSWDNPVYKEGHLAILKGNLASEGAVAKISGVKNPQITGPARVFESEEECLEAILAGKINAGDVIIVRYEGPRGGPGMREMLAPTSAIIGAGLGDSVGLITDGRFSGGTYGLVVGHVAPEAYVGGTIGLVEEGDSITIDAKKKLLQVNVSEEELSQRRANWKAPEPRYQRGVLGKYAKLVSSSSLGAVTDLNLF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS3_CAMJD
Sequence: MGQKVNPIGLRLGINRNWESRWFPTKANLVENIGEDYKIRAFLKRKLYYAGISQILVERTAKKLRVTVVAARPGIIIGKKGSDVDNLRKELQDLISKDVNINIKEERKAGASAQLAAESVATQLEKRIAFRRAMKKVIQGAQKAGAKGIKVSVSGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGFAEARTTYGNIGVKVWIFKGEVLHKGMQPEKTEESAPAKKSRRTRRGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GCSH_CLAM3
Sequence: MTDQTSLQYTAEHEWVQVDGDVATVGITAYAADKLGDVVFVELPAVGDELAGGEVVGEIESTKSVGELFAPIDGTVTEVNDDVVASPDLVNSDPFGAGWLVKVRFEALPTLLSHDEYVALVGE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: YOBO_BACSU
Sequence: MVHFKNCPDPSLNANSQSHPEFSSELEHIKTRMQNFIKHSVTDQNIEVTDARVTAEGEVTSLLKERLDKEYYRLLSKITREVNVADFGAVPDGRDNTEAFRKAIGNGRVKVHVPAGEYLVQGIKLPSWTTIVGQGKGITVIKLHEDTPAHEWVITNDDYQNGNRNIFVQGMSLDWNPSRQCGVRNPGGQFSSCLTFAKVEYGWIKDVEAINAGLHGIDITSPTYDHLPDTDWTKDGSRYIWIDNCVTYGSGDDGITTHYSEYIFISNCHSGNPRGTEFAEGVSNSNGIEIDDGSRHVWLLNNFTSGNIRGVEVKAHELWPASQNVHIIGHISYRDVRAFDLRHIGHHQITDPESTTAYDVTLIDCSAVEPVFNSLYDAVTPRALVISAYKNVNVSGFTAIGDPDYDYKENPVVALQYRSQNITINGIKIRGFKKAGVDINLSGGSNKTDYIKISNFDIYKSAPKGISIGGGLYNVNILNGTMITDNGTVAIQSPNNQATILGVQSEGYSVAASIKGQTYQQVPINLKGGIQLATTSGFAVNQTSAVIAGTGDITARGERNAVISSSGGSSTEGSRALIASSNNAHIRGNQASRTILSSENIILEEPYTVAGGHQSIKWLLDSVRGNGTFAGAISSSLGGYGEYFESSTGQLIHTGTIVTLRGEKIVPANVGDYMLGVISETSAFISGASSFVWQGRYLTNEFGGFIYETVTDEESGELIRVPKQNPDYDTALEANYHSRAARDEWHVVGLVGQHYVRIDETVNQGDYLTAHNGIGTKATEGSWKVMKITSAYTSEKGYGIALTVIK
What are the official names of this protein?
Putative phage-related protein YobO.
Protein: ZDHC3_HUMAN
Sequence: MMLIPTHHFRNIERKPEYLQPEKCVPPPYPGPVGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYVYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEGLLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV
What is the function of this protein?
May also function as a calcium transporter.
What are the official names of this protein?
Palmitoyltransferase ZDHHC3, Acyltransferase ZDHHC3, Protein DHHC1, Zinc finger DHHC domain-containing protein 3, DHHC-3.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Note=Localizes to the Golgi cis cisterna.