PharMolix/UniProtQA huggingface dataset:
Protein: AROB_LEGPH
Sequence: MAKFELYAEVDVSISGHQYPIIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQSVLPSKQCDVVILEDGEEHKNQRSLFTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAASTYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGSFYQPQAVIIDLNTLKTLPEREFRAGIAEMIKYALLVGGSFFERIQEALQQGLTVHSPELPLLIAECCQVKAKIVEQDERESGLRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKMLIHAGLPHKIPNSIDLIQLRELMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNALINVVEGERK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_SPHAL
Sequence: MPGQMPVAPGTNPDQSFFDDLSGEVGDKGFLVTSTEDLFNWARTGSLWWMTFGLACCAVEMIHVNMPRYDMERFGVAPRASPRQSDVMIVAGTLCNKMAPALRRVYDQMSNPKYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGVMQLQRKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PANC_STRM5
Sequence: MIQTFNELGALRGQIAEWKREGLRVALVPTMGNLHGGHHSLVTLARQYADKVVASIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAGCDAVWLPSVEAMYPLGVDKTTRMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDAAVFGRKDYQQLAVIKQMVAELSFPIQIVGADIVRDDDGLAKSSRNQYLSAEQRPVATSIHRTLLGMREGYVAGQSRAQIEADATAALQADGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YADA_YERE8
Sequence: MTKDFKISVSAALISALFSSPYAFANNDEVHFTAVQISPNADPDSHVVIFQPAAEALGGTNALAKSIHSIAVGASAEAAKQAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARAFTSDTGVAVGFNSKVDAKNSVAIGHSSHVAVDHDYSIAIGDRSKTDRKNSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQVNANKKSAEVLGIANNYTDSKSAETLENARKEAFDLSNDALDMAKKHSNSVARTTLETAEEHTNKKSAETLARANVYADSKSSHTLQTANSYTDVTVSNSTKKAIRESNQYTDHKFRQLDNRLDKLDTRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSGYRVNESVALKAGVAYAGSSDVMYNASFNIEW
What is the function of this protein?
Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface and phagocytosis resistance (By similarity).  Promotes initial attachment and invasion of eukaryotic cells (Probable).  Also protects the bacteria by being responsible for agglutination, serum resistance and complement inactivation.  Gly-389 plays an important role in this protein; replacing it with increasingly large polar residues decreases expression levels and trimer stability.  Residues larger than Ser (Thr, Asn or His) significantly decrease serume resistance and bacterial autoagglution without affecting adhesion to host cells or host cell cytokine production (PubMed:17921300).
What are the official names of this protein?
Adhesin YadA, Protein Yop1, Trimeric autotransporter adhesin YadA, TAA YadA, Type 5 secretion system autotransporter YadA.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C- terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: FNTB_MAGO7
Sequence: MRHHTKNLRRRAIFLRTTPRGNMDSSSSVATSTSSSSNHRLVRSSEGSPSAGGDDIEEVIMTPGIATGRVQPAVSVAIPDLFTQLPPVKDDLATSTSKTQDETVAICLPYLAGSDANADVEHNAHGVPHIDRKKHVRFLRNMLRQLPAPFIAADASRPWFLYWSLNAMAILGENVKEDYAESLADTARSMQNESGGFSGGHGQTSHLATTYAVVLALAVVGDEEGLSLIDRRALWKWLCDLKEADGGFRMSLGGEEDVRGAYCAAVIISLLNLPLDLCKDSEAYIRDPTANLFTGLGDYVRKCQTFEGGISGQPDAEAHGAYAFCALGCLSLLGTPSETIPKYLNIERLISWLSSRQYAPEGGFSGRTNKLVDGCYSHWVGGCWPLIEACLNGPVKVSSLDVEPQPLFSREGLMRYILCCCQEQGKRGGLRDKPGKPSDAYHSCYVLSGLSSAQNRWQLVVGDDDMPAWMVSPFPNEEEIFDEKDRVGTVHPVYVIPEDKVAKVQTFFASRDGF
What is the function of this protein?
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  The beta subunit is responsible for peptide-binding.
What are the official names of this protein?
Protein farnesyltransferase subunit beta, FTase-beta, PFTase beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1KB1_LOXSA
Sequence: WIMGHMVNAIAQIDEFVSLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKWEYFNTFLGGLRKATTPGDSKYHEKLVLVVFDLKTGSLYDNQAYDAGTKLAKSLLQNYWNKGNNGGRAYIVLSIPNLDHYKLITGFKETLTKEEHPELMDKVGYDFSGNDDIGDVAKAYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYINKVYYWTVDKRASTRDALDAGVDGIMTNYPDVIADVLSESAYTAKFRIATYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsaSicTox-alphaIB1bi, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ESPG3_MYCTO
Sequence: MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRGAFVDRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADGACELLRGIVALRTGTGKTSNKTGNGVVALRNAQLVTFTAMDIDDPRALVPILGVGLAHRPPARFDEFSLPTRVGARADERLRSGVPLGEVVDYLGIPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRVLVSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLPDGQWFPGQRVSRDFSTQSS
What is the function of this protein?
Specific chaperone for cognate PE/PPE proteins.  Plays an important role in preventing aggregation of PE/PPE dimers.
What are the official names of this protein?
ESX-3 secretion-associated protein EspG3.
What is the protein family that this protein belongs to?
Belongs to the EspG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1758_SHEB8
Sequence: MELTLHEARVIGCLLEKEITTPEQYPLSLNSLTLACNQKTSREPVLELSETQVQIAVDSLNRKRLISEQSGFGSRVVKYKHRFCNTEFSELQLSAAALAIVCLLLLRGPQTPGELRTRSNRLHEFKDVIEVEDCIRQLMNREKPFLKQLPREAGRRESRYVELFSAASSQLETAQPESASHTVAHVAVSLDAEPLELTKRVTELEQQVAELTQKLDELIASLS
What are the official names of this protein?
UPF0502 protein Shew185_1758.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: CTAA_LISMO
Sequence: MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEFMHRMTTGISSIFVIVLAICAWIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYIMALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKLRVNIYALTIYTYLAVYTGALVRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYRVLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSNRLRIK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRB_CLOBB
Sequence: MGEFKIHSKFKPMGDQPQAIDTILKSIKQGNEFQTLLGVTGSGKTFTMANIIENLQRPTLILAHNKTLAAQLCSEFKEFFPENIVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIVASVSCIYGLGNPDEYKKLTISLRKGMQKERDEIIKKLIEIQYERNDIDFSRGTFRVRGDLLDIIPSSTSSKGIRIEFFGDEIDRIREFDVLTGTIIGERNHVSIFPASHFATSKETVERSLGEIENELENRLRELNSQEKLLEAQRLRQRTNFDIEMIREMGYCSGIENYSRILDGRAPGTPPKTLIDYFPEDFLLFIDESHVTLPQVRAMYAGDRSRKNTLVDYGFRLPCAYDNRPLKFEEFEKKINQVMFVSATPAQYELEHSQSIAEQVIRPTGLLDPEIIIKPVKGQIDDLYTEIQETISRGYRILITTLTKRMAEDLTKYMIELGVKATYMHSDIDTIERMKIIRDLRLGEYDVLVGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNSESKVIMYADNITKSMKKAISETERRRKIQTEYNEEHGIIPQTINKEVRELIEATKVAEESTEYGMEVTKSLTKKEAKKLIKEYTDEMKLAAKNLQFERAAQLRDKIEELKGKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPF_ECOLI
Sequence: MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF
What is the function of this protein?
(Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA-EC536-mediated toxicity.
What are the official names of this protein?
Outer membrane porin F, Outer membrane protein 1A, Outer membrane protein B, Outer membrane protein F, Outer membrane protein IA, Porin OmpF.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: HACL2_HUMAN
Sequence: METPAAAAPAGSLFPSFLLLACGTLVAALLGAAHRLGLFYQLLHKVDKASVRHGGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSGTVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLCKFCVSVRRVRDIVPTLRAAMAAAQSGTPGPVFVELPVDVLYPYFMVQKEMVPAKPPKGLVGRVVSWYLENYLANLFAGAWEPQPEGPLPLDIPQASPQQVQRCVEILSRAKRPLMVLGSQALLTPTSADKLRAAVETLGVPCFLGGMARGLLGRNHPLHIRENRSAALKKADVIVLAGTVCDFRLSYGRVLSHSSKIIIVNRNREEMLLNSDIFWKPQEAVQGDVGSFVLKLVEGLQGQTWAPDWVEELREADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRGPLRWLDPGAFGTLGVGAGFALGAKLCRPDAEVWCLFGDGAFGYSLIEFDTFVRHKIPVMALVGNDAGWTQISREQVPSLGSNVACGLAYTDYHKAAMGLGARGLLLSRENEDQVVKVLHDAQQQCRDGHPVVVNILIGRTDFRDGSIAV
What is the function of this protein?
Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner.  Involved in the phytosphingosine degradation pathway.
What are the official names of this protein?
2-hydroxyacyl-CoA lyase 2, Acetolactate synthase-like protein, IlvB-like protein.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PLSC_SALTY
Sequence: MLYIFRLIVTVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAENYGNAIYIANHQNNYDMVTAANIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRAKAHSTIAAVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTGAFHAAIAAGVPIIPVCVSNTSNKVNLNRLNNGLVIVEMLPPVDVSEYGKDQVRELAAHCRALMEQKIAELDKEVAEREATGKV
What is the function of this protein?
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position.  This enzyme can utilize either acyl-CoA or acyl-acyl-carrier-protein as the fatty acyl donor.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-AGP acyltransferase, 1-AGPAT, Lysophosphatidic acid acyltransferase, LPAAT.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AKAP5_HUMAN
Sequence: METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNKINNLLQ
What is the function of this protein?
Multivalent scaffold protein that anchors the cAMP-dependent protein kinase/PKA to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors (PubMed:1512224).  Association with the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.  Plays a role in long term synaptic potentiation by regulating protein trafficking from the dendritic recycling endosomes to the plasma membrane and controlling both structural and functional plasticity at excitatory synapses (PubMed:25589740).
What are the official names of this protein?
A-kinase anchor protein 5, AKAP-5, A-kinase anchor protein 79 kDa, AKAP 79, H21, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein.
What are the subcellular locations of this protein?
Postsynaptic recycling endosome membrane; Lipid- anchor. Note=Associates with lipid rafts.
Protein: CYSN_CELJU
Sequence: MSHQSELIAQDINAYLAQHEKKELLRFLTCGSVDDGKSTLIGRLLHDSKMIYEDQLEAVRADSSKHGTTGEKIDLALLVDGLQAEREQGITIDVAYRYFSTSKRKFIIADTPGHEQYTRNMATGASTCDLAIILIDARHGVMTQTRRHSYIASLLGIKHIVVAINKMDLLDFNESVFENIKADYLAFAAKLGMKDVMFVPISALDGDNVVNRSEKSAWYKGQTLMEILETVPIAGDKNYTDFRFPVQYVNRPNLDFRGFCGNVASGVVKVGDEVRVLPSGKTSHVKSIVTYDANLDEAFTGQAVTLTLTDEVDISRGDMLVLARDQVPQSNHVRAHLVWMTEKFMQPGSEYLFKFASKLVSGQIESIGYRVDVNTQEHSQVTHLQLNDIALVDVLLTQSVVADKYQQNRATGAFIVVDRLTNITVGAGMVVEQLQAEQTTPVNYSEFELELNALVRKHFPHWGAADLRKLLK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: ATP6_MYCMM
Sequence: MTESILAAQIEVGEHHTATWLGMTVNTDTVLSTAIAALIVLALAFYLRSKVTSTAVPGGVQLFFEAITIQMRGQVESAIGMRIAPFVLPLAVTIFVFILISNWLSVLPVQYTDEHGQTTELLKPAAADINYVLALALFVFVCYHAAGIWRRGIVGHPIKLLKGHVAILAPINLVEEIAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKSFDLFVGAIQAFIFALLTILYFSQAMELEEDHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RF2_STAAC
Sequence: MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC241_SACU7
Sequence: MFHHRGGCTPRAQTPYAANVPIVAEQQQFQQQIDQTANAMGNFQLNDNAYSFTQPAQQPQQPSSRKVANQLYPVDLFTELPPPIRDLSLPPPPITISQDSIVTPSETSNVPYQYVRSTLNAVPKTSSLLKKTKLPFGIVIRPYLNLQDSSEYVPLNNDGIIVRCRRCRSYLNPFVAFIEQGRRWQCNICRFKNDVPFGFDQNLQGAPINRYERNEIKHSVMEYLAPIEYSVREPPPSTYVFILDVSQNAVRNGLLATSARTILENLESLPNHDGRTSVSIICVDHALHYFYVPLDDDYEESDDDDDEDDDDEEEDNEEEEEEEEDEEDDDDSITEAIQMFDVGDLSEPFLPMPSEELVVPLRYCKKNLEKLLKTIPEVFQDTHISKFALGPALKAASYLISNTGGKIEVISSTLPDTGVGKLKRRAEQGVLNTTKESSQLLSCQDSFYKTFTIECSKMQITVDMFLASEEYMDVATLSHLSRFSGGQTHFYPGFNATSLNDVTKFTRELSKHLSMDISMEAVMRVRGSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFEISIEDSLVAEHCYLQVSTLLTLNTGERRIRVMTLALPTTESGREVYASADQLAITDFITQNAVAKALNSSMDSARDLITKSLQDILSAYKKEISMSNITAVTSLNLCANLRMLPLLMNALGKHIAFRPGMVPSDYRASSLNKLETEPLHYLIKSIYPTVYSLHDIPDEVGLLDSNRETKLPDPINATASLFERYGLYLIDNSTELFLWVGGDAVPELLNDVFNTDNISNVPVGKSELPVLIDSPFNVRLRNIISKIRENNDTITFQSLYTIRGPSINEPANLTAEREMASLRLWVSSTLVEDKILNCASYREYLQSMKTAINR
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24-1.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATAT_PLAKH
Sequence: MNIPPEKMHNLEIKKHSRVDLLLLRSSDFHSFRKLQRDVDEMGLLSSTEQHLSGILTTLDNITDQDNTLYCLTQEGELIGMLKIGTKRLYLYNGKDLHCRSCACLLDFYIQRNFRKRGLGLELFNFMLKDKAISPSRLCYDNPSYKLQSFLKKHFSPCALIKQPNNFVIFAEYFGEPEMGPFGQ
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: MNMA_LACGA
Sequence: MVDNSEIRVVVGMSGGVDSSVSALLLKQQGFDVVGVFMKNWDDTDDSGVCTATEDYEDVKKVADEIGIPYYSINFEKDYWERVFEYFLNEYKKGRTPNPDVMCNKEIKFKSFLDFAMDLDADYIAMGHYAATKVDENGIVHMMRPKDGNKDQTYFLSQLSQDQLKKVIFPLANLTKPQVREIAIDAGLATAKKKDSTGICFIGERNFKKFLSEFLPAQSGKMVTPDGKVVGEHAGLMYYTIGQRSGLGLGSTKESTDPWFVVGKDLKKNELIVEQGYDSKLLYATSLDASGVSFFTGQPEHDIDLKCTAKFRYRQPDVGVTMHYHAKDNTVHVEFDEPARAVTPGQAIVFYNGEECLGGATIDRAYQNEKQLQLV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_ACIBC
Sequence: MTTTTTKFRDVEIRAPRGTELTAKSWLTEAPLRMLMNNLDPDVAENPKELVVYGGIGRAARNWECFDKIVDTLKNLETDETLLVQSGKPVGVFKTHKDAPRVLIANSNLVPHWANWEHFNELDAKALAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGDLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQASIDFRLRTRYVDEQATDLDDALARIDRYTKEGKAISIALHGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPVGWTWEEYRERAKTEPEAVVKAAKQSMAKHVQAMLDFQKMGVPTFDYGNNIRQMAKEEGVANAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIYKTDAKVKELIPDDEHLHHWLDMARERISFQGLPARICWVGLGLRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGVVIVCDGTDEAAARIARVLTNDPATGVMRHADAGYEIAINCAKEQGLHLPMITQ
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYV10_ASHGO
Sequence: MSVMNEPTVDFHLKLNEQQFHIPNELLKRNLKQCQKLIDKEATALEKSFEELDRLVRNPQNDESSMALLNEIIQKVERLERKLTKRVNVELQLLQRIDARIKYYQQLDQIKQSGDRNRLLEWYQSYTNLLISDYLTRNSMYEGEDDISCSSTPPPARLKRKLSSASSQLTTATSNNDPDRSHVNPGVEYLKQQGLDLLLDYDILLTTNRISKQLTINHELGPLLDWIKENATYLKHTSSMLEFEARFQEYIEYVKVEDYSKAITCFQTHLVKFLYSNPLDLQQAAGLLVFIKACKSNISSYVPTPRHEEIVKQQTLLQSKEDFWSFFFLKLPKSSKKDHKTNIEVKNNELAASVDIKRYMELLDDRRWEKLNEMFLKAYYSMYGISYHDPLLIYLSLGISSLKTKDCLHERRAFVSPNNELSEFLSSEVLRNACPVCSPEFAPIAQKLPYAHQVQSRLFENPVMLPSGNVYDAEKLKALAQTLRKRKLVVMGEDEVLDPIAGHTYALTDFITMYPT
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein FYV10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.