PharMolix/UniProtQA huggingface dataset:
Protein: VNS2_EHDV2
Sequence: MEQKQRRFTKNVFVLDQKRKTICGQIAARQSLPYCQIKIGRNFALRAVATPEPKGYVLEICDVGAYRIQDGNDVISLMISADGVEGTQERWEEWKFESDLMRTNGHSSKYKRSVGRREIKVSKGMGIVPPYTRNDFDRRELPELPGVQRSKYDIRELRQKIREEREKGAVEQPHKPAFKTERGMNRPDSDEDQNPAGGVVNDWTCETQKRDQEAERREALEIRLADNDRESKHSNWIVRGRGKILKEVKNSFRTQEVERKKSDMGEVIIEEDDEDSEEEEGARASYITSAYIERISRIRKIKDERLSMLASMMPQQSGEYTTTLFIKKQKWDNVPLYLIDEMQKKYELQSVGSCERVAFVSKGTNLIILPVASNPR
What is the function of this protein?
Single-stranded RNA-binding protein.
What are the official names of this protein?
Non-structural protein NS2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS2 family.
Protein: GLYA_YERPP
Sequence: MLKREMNIADYDADLWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKALFGADYANVQPHSGSQANVAVYSALLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDESGQIDYEDLARQAEIHKPKMIIGGFSAYSGIVDWAKMREIADSIDAWFFVDMAHVAGLVAAGVYPNPVPHAHIVTTTTHKTLAGPRGGLILAKGGDEDLYKKLNSSVFPGNQGGPLMHVIAGKAVALKEAMEPEFKIYQQQVAKNAKAMVAVFLERGYKVVSGGTDNHLFLLDLVDKDITGKDADAALGRANITVNKNSVPNDPKSPFVTSGVRIGSPAITRRGFKEAESRELAGWMCDVLDNINDEATIERVKQKVLAICARLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_XANOR
Sequence: MEQGVIERARELRRRIENADHRYYDLADPEITDAQYDQLFRELQELEQKYPELVTADSPSMRVGGAVRKSFVKVRHSIPMLSLANAFDEVEVKNFVDRIFRRMGSSNPLEFSVEPKFDGLAISLRYELGKFVQGVTRGDGDVGEDVSENIRTIRSVPLKLKGNNVPAILEVRGEVYMPRDGFSEFNKRAMARGEKLLANPRNGAAGSLRQLDSRISAQRPLSFFAYGVGLIQVEQDLFEEIPQSIASTHSAMLAQLRAWGFPVSSLVEVVQGSDGLLAYYQRIGEARDGLPFDIDGVVYKLDDLAGQREMGFVSRAPRWALAHKFPAQEQSTTVEAIEIQIGRTGAATPVARLKPVHVAGVIVTNATLHNADQIARLDVRVGDTVIVRRAGDVIPEVAAVVADQRPPATQSWQMPTQCPVCGSEIVREEGQAVWRCSGELTCPAQRKEAFRHFVSRRAMDVDGLGEKFIEVLVDSGVVQGVADLYLLTVDQLLQLRMISTAESPHAFLREAREHLASGAYAQLEATLVGIGVDLAGEREVPQTWQADLLRAGLPTFDWNRKKIATKWAENLIEAIETSRDTTLERFLFALGIEHVGESTAKALSAWFGDLDLIRHLPWPLFKRVPDIGGEVARSLGHFFDQPGNQKAIDHLLARKVRIGDTHPPSPKLRGELRLANLLEDLEIPKVTPIRAAQIATAFGSIDALRNGGPEPLVEAGVPQSVAESLATWLLVPANDTLAVKAQKKLSALLAMMPEAGEEKTGPLDGQTVVITGTLAALTRDAAKQRLEALGAKVAGSVSKKTAFLVAGEEAGSKLDKAQSLGVEIWDEARLLAFLGEHGQQR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DCTR_PRIMG
Sequence: MNKKAWTVLLIEDDPMVQEVNRQFIEQVEGFTVIAAASNGLEGVQLIKQHQPDLTIIDMYMPSQDGLTTLQQIRANGYKTDVIAVTAASDIETVRKVLQYGAVDYIMKPFKFERMKQALEQYRSFQVKISQKEHITQSELDSMLFQQFEEKADLLPKGLNAVTLRRIQQYLSEQNHPISAEEVADGVGIARVTARRYLEFLEQENELKLSVEYGRVGRPINRYMLKIN
What is the function of this protein?
Member of the two-component regulatory system DctS/DctR.  Essential for expression of DctP (By similarity).
What are the official names of this protein?
Probable C4-dicarboxylate response regulator DctR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHA_SALAR
Sequence: MALPIILDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPDKTLRNVLRMLTLLKRSDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQNCTAVELMAKTLRESPQPVTLVATGPQTNVALLLNSHPELHAKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVLMAGLDVTHKAQIHTADIERFRAIGNPISTIVAELLDFFLEYHKDEKWGFTGAPLHDPCTIAWLLKAELFTTVERWVGVETQGKYTQGMTVVDYYFLTGNKPNATVMVDVDREGFVDLLAERLKFYG
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: GT5_ORYSJ
Sequence: MMEKHGGKVTSDRRAGRRQHGQRCSASDAAPLVVVVILIVAALFLILGPTGSSSFTVPRIRVVFNEPVHVAVAAPPPPPPPAQMQAGANASSEEDSGLPPPRQLTDPPYSLGRTILGYDARRSAWLAAHPEFPARVAPAGRPRVLVVTGSAPARCPDPDGDHLLLRAFKNKVDYCRIHGLDVFYNTAFLDAEMSGFWAKLPLLRMLMVAHPEAELIWWVDSDAVFTDMLFEIPWERYAVHNLVLHGWEAKVFDEKSWIGVNTGSFLIRNCQWSLDLLDAWAPMGPRGPVRDRYGELFAEELSGRPPFEADDQSALIYLLVTQRQRWGDKVFIESSYDLNGFWEGIVDKYEELRRAGRDDGRWPFVTHFVGCKPCRRYADSYPAERCRRGMERAFNFADDQILKLYGFAHESLNTTAVRRVRNETGEPLDAGDEELGRLLHPTFRAARPT
What is the function of this protein?
Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
What are the official names of this protein?
Probable glycosyltransferase 5, OsGT5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: Y473_STUS1
Sequence: MSIRDWPASERPREKLLDQGAAALSDAELLAIFLRTGVAGKSAVDLARYLLAEFGSLRALLEADLDQFSAHLGLGPAKFAQLQAVLEMGRRHLAERLRRDSALESPQAVRDYLKARLRHEPHELFGCLFLDAKHRVLAFEVLFHGTIDGASVYPRQVVKRALAQNAAAVILTHNHPSGVAEPSQADRQLTQRLKDALALIDVRVLDHFIVGDGEPLSMAEYGWM
What are the official names of this protein?
UPF0758 protein PST_0473.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: METAS_SHIDS
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEFFRDVEAGLDPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_PELUB
Sequence: MNSLDANTRNTKSKGDVRSLRSAGNIPGIIYGGPDQNQKVTVLKKTLKSLIDKGSFLSNIITLNLDGKPQNVLPREITYNVISDEPTHIDFLRVVPGVKIRIEVPVVFINHETSPGLKRGGVLNIVRRKIELKCPSEKIPSAITIDLDGVDIGESFKISSVKLEEGVTPTIIGRDFVIATLAAPTVMKEPEKPAEAEAEAAEDGKEAAPAAEGDKKDDGEKKATEEKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: VPN6_BPPHE
Sequence: MNYPKREKVVEVSLASGTYSVFPRRLGVTTNDAMSIVNGAMKGAELPMIPVHKLADRDSELTYVNAFQIQTATENIVDVPERITSLYTKPEDETPEDEEVRLGTINNYFSLR
What are the official names of this protein?
Virion protein 6.
What are the subcellular locations of this protein?
Virion.
Protein: KAD_BACC4
Sequence: MNLILMGLPGAGKGTQAEQIVAKYNIPHISTGDMFRAAMKAETEMGLQAKSFIDKGALVPDEVTIGIVRERLSQDDCVRGFLLDGFPRTVAQASALEEIMKDLGKKIDYVLNINVDSGLLLKRLTGRRICKECGATYHLEFNPPAKADVCDKCGGELYQRSDDNEETVANRLDVNIKQTKPLLDFYEELGYLQSINGEQDINKVFADIDVLIGGLA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TWSG1_HUMAN
Sequence: MKLHYVAVLTLAILMFLTWLPESLSCNKALCASDVSKCLIQELCQCRPGEGNCSCCKECMLCLGALWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVSFPVAEELSHHENLVSFLETVNQPHHQNVSVPSNNVHAPYSSDKEHMCTVVYFDDCMSIHQCKISCESMGASKYRWFHNACCECIGPECIDYGSKTVKCMNCMF
What is the function of this protein?
May be involved in dorsoventral axis formation.  Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.  In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes.  May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation.  May play a role in thymocyte development (By similarity).
What are the official names of this protein?
Twisted gastrulation protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the twisted gastrulation protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRGM1_CYPCA
Sequence: MGKIIFYDDRNFQGRSYDCMSDCSDISSYLSRVGSIRVESGCFMVYERNSYMGNQFFLRRGEYHDMQRMMSMGMIFDTIRSCRMIPPYRGSYRMRIYERDNFGGQMHEVMDDCDNIMERYRMSDWQSCHVMDGHWLFYEQPHYRGRMWYFRPGEYRSFRDMGYSNMRFMSMRRITDIC
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin M1, Gamma-M1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: CBP4_PICST
Sequence: MSAKPLWYRWARVYFAGSCIIGTGVLCFIYTTPTDEQLIASFSPEIREDYEKNKAYRQREQQELMEIVKKTSQSDEPVWKTGPIGSPLEKEQRNLNQQLIDYNQFEKKRAEEYQREQIDKAQEELLEVEKLAAQAKKGYWWNPFSSK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PGH1_HUMAN
Sequence: MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
What is the function of this protein?
Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response.  The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes.  This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins.  The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons (PubMed:7947975).  Involved in the constitutive production of prostanoids in particular in the stomach and platelets.  In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection.  In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells (Probable).  Can also use linoleate (LA, (9Z,12Z)-octadecadienoate, C18:2(n-6)) as substrate and produce hydroxyoctadecadienoates (HODEs) in a regio- and stereospecific manner, being (9R)-HODE ((9R)-hydroxy-(10E,12Z)-octadecadienoate) and (13S)-HODE ((13S)-hydroxy-(9Z,11E)-octadecadienoate) its major products (By similarity).
What are the official names of this protein?
Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the prostaglandin G/H synthase family.
What are the subcellular locations of this protein?
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RNH2_COXBN
Sequence: MDAPFAKTPSNLLIAGVDEAGRGPLAGPVITAAVILNPEIIIEGLADSKKLSLKKREELYEKIITNCKAFAIARADVEEIDRLNIFRATLLAMQRAINQLSIQPDKVLIDGHCCPDLPYETQAIVQGDQNVPAISAASILAKVTRDREMLKYDAQYPDYGFAIHKGYGTKAHLAAIHRFGITPVHRKSFEPVRQLKLFIPEE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPA_STAAT
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLILTETTTFKAVPGHGIEATIDHHYILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GYRB_ACIBZ
Sequence: SYKVSGGLHGVGVSVVNALSSKLELTIHRAGHIHQQEYKHGDPVYPLKVIGDIETTGTTVRFWPSAETFSQTIFNVDILARRLRELSFLNAGVRIVLRDERVALEHIFDLEVGLSEKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4PE_SINFN
Sequence: MWAYIFGAVCPRKGKGAGLVLPYCDTEAMQEHLAEIGRSVDDGAHAVLILDQAGWHVTPKLKVPDNITLMFLPPRSPELNPVENVWQFMRDNWLSNRIFKDYDDIVTHCCAAWNKLVDQPWKIMSIGLREWAHRS
What are the official names of this protein?
Uncharacterized protein y4pE/y4sA.
Protein: SELD_SHEON
Sequence: MSNSTLPSTDSIKLTEYSHGAGCGCKISPKVLTTILASQLPVFTDPNLLVGNQSRDDAAVYKLNEEVGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPMMAIAILGWPINKLPAEIAQQVVDGGRQACMEAGIMLAGGHSIDAPEPIFGLAVTGQIALTDLKQNDTAKAGDRLYLTKPIGIGILTTAQKQKKLKDEDSHIAVNAMCQLNSIGAQIAKINGVNALTDVTGFGLAGHLLEMCQGAKLTAKLKLDAVPLLPRALDYLAQGCVPGGTHRNYDSYGEHLPELTDHQKAILCDPQTSGGLLVAVSSEAEAELVALLNANQIEPICIGSLEAPTTATNVVLC
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ENL_HUMAN
Sequence: MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT
What is the function of this protein?
Acts as a key chromatin reader in acute myeloid leukemia by recognizing and binding to acetylated histones via its YEATS domain, thereby regulating oncogenic gene transcription.
What are the official names of this protein?
Protein ENL, YEATS domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSA_SHESM
Sequence: MSNKIINLGSIEIANDKPFVLFGGMNVLESRDLAMSIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIFEEIKKTFNLPLITDVHEPYQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIILCERGSCFGYNNLVVDMLGMDEMKQSGYPVIFDATHALQRPGGRADSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLENYLKQMKAIDDLVKSFDPIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_BACCQ
Sequence: MLNIGPFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEILTFAVRRMDIFDAKQPNLLERLDVKKYTLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLKASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATLPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGAKDPIKMAQAMKLSIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_ECOBR
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: PFKA_CITK8
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENVRAVAIENLKKRGIDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSRDDLVAEIKAGIAKGKKHAIVAITEHMCDVDELAHYIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGSYAIELLLEGFGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QSOX2_MOUSE
Sequence: MAAARAVARDPGAYARQPPSLRAARLPRLLFLLAVVAAVGPREGGGARLYREGSDAVWLLDSGSVRSATGNSSAAWLVQFHSSWCGHCIGYAPTWRALAADVRDWAAAIRVAALDCAEEKNQDVCRTYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHTEGTWPPACPPLDPIQSSDILSFMDSHSGQYHAIVFESNGSYVGREVILDLIPYENIMVSRALDTDKAFLGTLGITSVPSCYLIYPNGSHGLVNVAKPLRSFFSSHLKSLPDVRKKSLFLPEKSNKEEKSEVVVWKEFDRAKLYTADLESGLHYLLRVELAAHRSLAGAQLKTFRDFVTVVAKLFPGRPAVKKLLETLQEWLANLPLDKIPYNAILDLVNNKMQISGIFLTSHVKWVGCQGSRLELRGYPCSLWKLFHTLTVQASTHPEALAGTGFEGHPQAVLQAIRRYIRTFFGCKECGEHFEEMAKESMDSVKTPDQAVLWLWRKHNMVNSRLAGHLSEDPKFPKVPWPTPDLCPACHEEIKGLDSWNEGQVLLFLKQHYSRDNLVDAYSVDQGSPGEWEAQGREQEEGKGLNPSGKSWRHHDTGSLRPPHILGPRTDLSKSLHHRLDLRLQSPQGPQALKEAKAVVPFLGVGFSSLDMSLCVVLYVASSLFLMIMYFFFRVRSKRWKVRLYHPAV
What is the function of this protein?
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.  May contribute to disulfide bond formation in a variety of secreted proteins (By similarity).
What are the official names of this protein?
Sulfhydryl oxidase 2, Quiescin Q6-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPA_CYAPA
Sequence: MVSIRPDEISSIIRQQIEQYDQEIQVSNVGTVLQVGDGIARVYGLDKVMSGELLEFEDGTIGIALNLEADNVGVVLMGDGRNILEGSSVRATQKIAQVPVGDAVIGRVVDALARPIDGKGDIATTDTRLIESSAPGIISRKFVYEPLQTGITAIDAMIPIPRGQRELIIGDRQTGKTAVAIDTILNQKGQGVVCVYVAIGQKASSVAQVVGVLQEKGALDYTVIVAANADDPATLQYLAPYTGASIAEYFMYKGQHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPQLGEGSMTALPIVETQAGDVCAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFDELKAFSQFSSDLDKATQLQLARGERLRELLKQQQYAPLPVEEQVAVIYTGINGFLDNIETKQVSAFISNLRENLSVKRAKFGEIIRSEKALTAEAENLLKDAISDCKQAFLSNI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, cyanelle, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Peripheral membrane protein.
Protein: TT39B_RAT
Sequence: MALVGSRVELDADEDIFEDALETISRSPSDMATSGFHFVPCDTKRTSRQLGAPAVGRAEGSSAKVDLKSGLEECAAALNLFLSNRFKDALELLRPWAKESMYHALGYSTIVVLQAVMTFEQQDIQNGISAMKDALQTCQKYRKKCTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHVIQKNKEEQHFFYEFEGGVKLGTGAFNLMLSLLPARIIRLLEFIGFSGNRDLGLLQLREGASGSSMRSPLCCLTILAFHTYISLILGTGEVNVAEAESLLAPFLQQFPNGSLILFYHARIELLKGNAEKAQETFRKCISVQEEWKQFHHLCYWELMWIYIYQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEEVAVTKENVVSLFRQVDGLKQRIAGKSLPTEKFAVRKARRYSPSSGVPGKLVLPALEMMYVWNGFSIVGKRKDLSENLLVTVEKAEEALQNQNFTDYSVDDECLVKLLKGCCLKNLQRPLQAELCFNHVLESEKLLKYDHYLVPFTLFELAFLYKSQGEIDKAIKVLETARNNYKDYSLESRLHFRIQAALHLWKKPSSD
What is the function of this protein?
Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).
What are the official names of this protein?
Tetratricopeptide repeat protein 39B, TPR repeat protein 39B.
What is the protein family that this protein belongs to?
Belongs to the TTC39 family.