PharMolix/UniProtQA huggingface dataset:
Protein: EFP_ECO45
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EHD2_ORYSJ
Sequence: MLLSDLSSDQEATGSNSHGGGGGDRMVVGSHGAAHVVLSNLFLPPAAAAAATMLLPAAPVMVRPAAMAAAQEPRAKKKRSLPGNPDPEAEVIALSPRALVATNRFVCEVCNKGFQRDQNLQLHRRGHNLPWKLRHRAAAVSAVTTAAPAPRKRVYVCPEPTCVHHDPARALGDLTGIKKHFSRKHGEKRWRCERCGKRYAVHSDWKAHVKNCGTREYRCDCGILFSRKDSLLTHRAFCDALAEESARLLAAANNSSSITTTTCNNSNISSNNNNNNINSISNSNNLLITSSSSSPPLFLPFSTTPAENPNPNQLLFLQQHQAAHHQLLLPQFQQPPSSPPAYFDHLAFGGGGGVITGSSCNDDNSSIAGDVMVAAGGDSVSFGLTSEGSVTMHAGDVGRRRLTRDFLGVDHDAGEVDELELDELPADLSTTAAACQGCNFAAATTAACCATDFTTGSRQYLGRLPPVNETWSHNF
What is the function of this protein?
Transcription activator that acts as a flowering master switch in both long and short days, independently of the circadian clock (PubMed:18790997, PubMed:18725639, PubMed:18774969, PubMed:19304997, PubMed:24280027).  Promotes flowering upstream of HD1 by up-regulating FTL1, FTL4, FTL5, FTL6, EHD1, HD3A and RFT1 (PubMed:18790997, PubMed:18725639, PubMed:18774969).  Seems to repress FTL11 expression (PubMed:18725639).  May recognize the consensus motif 5'-TTTGTCGTAAT-3' in target gene promoters (PubMed:18725639).
What are the official names of this protein?
Protein EARLY HEADING DATE 2, Ehd2, Protein RICE INDETERMINATE 1, OsID, OsID1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HTPX_PARL1
Sequence: MNTVKTGMLLAAMTALFMGLGFLIGGPKGAMIAFFIAAAMNLFAYWNSDKMVLRMYKARQVDETTAPNYVGIVRQLAQNAGIPMPATYIIDNPQPNAFATGRDPEHAAVAATTGLIKMLTPEELAGVMAHELSHIKNRDTLIMTVTATIAGAISMLANFALFFGGNRNNAGGLIGTLALAILAPMAAALVQMAISRTREYSADAGGAEISGNPLWLASALQRIDEAARRAPNEAAEANPATAHMFIINPLNGRGRDNLFSTHPATGNRIDALRRIAETMGSRSRPWG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOPR_ACIGI
Sequence: MSPAKDVKVYKKILEQNKDIQDLLDKIVFDAQHGQIWFDENRMLLMHTSILGFLRKDLYQMLGLERTKRFFIRCGYQAGMRDAEVTSKLRPNLNEAEAFMAGPQMHGIRGMVQVEVNELHLSHDLKQFYADFNWLNSFEAEVHLSEFGASDQPACWMLLGYACGYSSFVMGQTIIYQETHCVAQGDEHCRIIGKPLSEWENADELIRFMSPDAVSDEIIALQAELNQLKKNIYTEAESDYTMFNAVGESVAYRKVCDLLKKAAGSKVAVLLQGETGVGKEAFARGIHNGSQRQAQPFVAVNCACIPPDLIESELFGVEKGAFTGAVQSRMGKFERAHGGTIFLDEVVELSPRAQAALLRMLQEGEFERVGDSRTRQVDVRLVAATNEDLEQAVKDGKFRADLYYRLNIFPVIIPPLRERREDIPLLINHFLARFENMYNKTLKGLSDKAKNFMMKYDWPGNIRELENLLERATLLTDHQQEIKLDSLFPQHKDLEAVGETAQSLINVEDLFSENFSLDQLEQNIIRSAMDKSQQNVSEAARMLGISRATLDYRLKKITLG
What is the function of this protein?
Involved in the regulation of the phenol degradation pathway.  Activates phenol hydroxylase expression in the presence of phenol.
What are the official names of this protein?
Phenol regulator MopR.
Protein: HRCA_BURCM
Sequence: MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEVADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ARNF_PSEA7
Sequence: MNVPRGWLAALGSVLLVSAAQLGMRWGMSRLPLPEAWAGQTPEHAALLAVALAVAAYAASLLCWLAALRHLPLGRAYSLLSASYALVYLLAASLPAFEETFTTGKTLGVGLVVLGVLTVNARRTAAAPAHHPSRKAL
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCOCB_DANRE
Sequence: MDGDIENQVELEEKTRLINQVLELQNTLEDLSARVDAVKEENLKLKSENQVLGQYIENLMSASSVFQTTDSKSKRK
What is the function of this protein?
Positive regulator of amino acid starvation-induced autophagy.
What are the official names of this protein?
Short coiled-coil protein B.
What is the protein family that this protein belongs to?
Belongs to the SCOC family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
Protein: SOT11_ARATH
Sequence: MFTFFTILSLCFKSWEQIITMEASKEAHHLPNYMKDDNVSQETKNLITSLPSDKDFMGYGLYNYKGCWYYPNTLQAVLDVQKHFKPRDTDIILASLPKGGTTWLKSLIFAVVHREKYRGTPQTHPLLLQNPHDLVPFLEVELYANSQIPDLAKYSSPMIFSTHMHLQALREATTKACKTVYVCRGIKDTFVSGWHYRNMLHRTKMDQATFELMFDAYCRGVLLYGPYWEHVLSYWKGSLEAKENVLFMKYEEIIEEPRVQVKRLAEFLECPFTKEEEESGSVEEILKLCSLRNLSNLEVNKNGTTRIGVDSQVFFRKGEVGDWKNHLTPQMAKTFDEIIDYRLGDSGLIFQ
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor.
What are the official names of this protein?
Cytosolic sulfotransferase 11, AtSOT11.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_PSYCK
Sequence: MDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKSTPYGQLENAAIGIKDSKIAWIGAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYGGNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEELFAQSEKRLLALVKEGVTSIEIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWLPILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQGLSSDHLEHLVEDDIKKMATSNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCNPGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALGLAHKGRIEVGCDADLALWDITRPADLAYQMGLNPIEGIMIKGAWR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAPR1_XENLA
Sequence: MEDKKEEGESEIQEHGPEHWFSKWERQCLAEAEQEDQPEEEAEQSQQKLWHLFQNSATAVAQLYKDRVCQQQGLSLWVPFQNAATAVTNLYKESVDAHQRSFDLGIQIGYQRRNKDVLAWVKKRRRTIRREDLISFLCGKVPPPRNSRAPPRLTVVSPNRATPTETGSSVETDLQPFREAIALHGLSGAMASISVRSSTPGSPTHVSGSSNTGRRRNGLHDVDLNTFISEEMALHLDNGGTRKRSSAQCGDVITDSPTHKRNRMI
What is the function of this protein?
Acts as a central player within a network of stress response pathways promoting cellular adaptability.  Functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage.
What are the official names of this protein?
HUWE1-associated protein modifying stress responses, Telomere attrition and p53 response 1 protein.
What is the protein family that this protein belongs to?
Belongs to the TAPR1 family.
Protein: Y484_MYCTU
Sequence: MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAAIEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR
What are the official names of this protein?
Uncharacterized oxidoreductase Rv0484c.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DEF_STAES
Sequence: MITMKDIIRDGHPTLREKAKELSFPLSNNDKETLRAMREFLINSQDEETAKRYGLRSGVGLAAPQINEPKRMIAVYLPDDGNGKSYDYMLVNPKIMSYSVQEAYLPTGEGCLSVDENIPGLVHRHHRVTIKAQDIDGNDVKLRLKGYPAIVFQHEIDHLNGIMFYDYIDANEPLKPHEEAVEV
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SYP_THEPX
Sequence: MRLSQLLVPTLREIPAEAEIPSHILMLKAALMRKLASGVYIYLPLGQRVLRKVEQIVREEMDRAGSQEVLMSALIPAELLKESGRWDVFGPEMFKLKDRNERDFCLGPTHEEVFTDLIRNEVKSYRQLPLILYQIQTKFRDERRPRFGVMRSREFIMKDAYSFDVDWEGLDKSFNKMYEAYCRIFDRCGLKYLVVEADSGAMGGKDSKEFMVISSIGEAVIAYCDNCGYAANEEKAECLINQEIVEEMLPKEEVYTPNVRTIEELVNFLGITPNKFVKTLIYKAKDNVVAALVRGDRDLNETKLLNILGIREEELELADASIVEKVTGAKVGFAGPIGLKGEVMIIVDNEIPQMRNFIVGANETDYHIKNVNYGRDFKADVVADIKNVIEGDKCPRCGSPLKIDRGIEVGHIFKLGTKYSDALGAKYVDEEGNEKPIIMGCYGIGINRTVAAIIEQHHDEKGIIWPMSVAPYHVIIVPVNVSNEAQNRVAEDIYAALQKEGIEVLIDDRDLRAGVKFNDADLLGIPIRITVGKKVDDGIVEIKLRENEEAEEVKISDVVEKVKNIIKEKM
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMP10_YEAST
Sequence: MFKRIAIAQIRTYTNGVVFKTASKPKRRWIPWTIFGGSFLGGWYLTQHMTFTDLLAYWRYDALPKNADEVVKYHADLNRRLNGLPIVKQLENAGFVQVIANEEENLLVSRALNTPGGVAIPPRVYYNPSRRETVGLYHLGMKLTGYPFLIHGGILATVIEDLMKEAIRLEKGTKNINQETKNLSISYKFPTLANQFVVVRTTDLQQYGNKTKLKAELMDQSGNRTLVKANATFSSEQGNPKEEK
What are the official names of this protein?
Uncharacterized mitochondrial membrane protein FMP10.
What is the protein family that this protein belongs to?
Belongs to the FMP10 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PRMC_THEYD
Sequence: MKALDKIREIVNKFSFNIREAQEIICHVLKIDKIQLYTENPEITSEQAHTIKSLIERRLKKEPLQYIIGECYFYNIKIKVGRGVLIPRPETEILVEQVLERQKLISNTGNRILDLCTGSGCIALAIGKNAPEFQIFGIDKSEKAVKYATENKALNNIKNVIFLVGDMFNPFKEKIFACITANPPYVKTDEISKLQPEIKNYEPLEALNGGEDGLNFYRKIIENAEKYLLNSGLIFLEIGQGQAKAVQNIALMSGFNVIEVVKDIAGIDRVMILQKSKSL
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: RL11_BORAP
Sequence: MAKKKAISWIKLQVPAAQAAPGAKIGQALGPHGVSGPQFVKEFNERTAKMEPGIVVPVIITVYSDKSFSFIVKTPPASILIKKAIGIESGSKKSNTDKVGTISKEKLMEIVRIKMPDLNAKSESAAFKIISGSARSMGVEVEK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RSMH_BURP1
Sequence: MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF150_ARATH
Sequence: MMGKHIQLSFAILIMFTIFVLGAVGDVDQGYKQQCYKTIDVNLCVTGECKKMCVRRFKQAAGMCIKSVPSAPAPNRCRCIYHC
What are the official names of this protein?
Putative defensin-like protein 150, Putative low-molecular-weight cysteine-rich protein 32, Protein LCR32.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SURE1_PYRAE
Sequence: MKILVTNDDGVHSPGLRLLYQFALSLGDVDVVAPESPKSATGLGITLHKPLRMYEVDLCGFRAIATSGTPSDTVYLATFGLGRKYDIVLSGINLGDNTSLQVILSSGTLGAAFQAALLGIPALAYSAYLENWNELLNNKEAVEIMGAVVSSTASYVLKNGMPQGVDVISVNFPRRLGRGVRAKLVKAAKLRYAQQVVERVDPRGVRYYWLYGRDLAPEPETDVYVVLKEGGIAITPLTLNLNAVDAHREVDMDSLNRMVEYINASL
What is the function of this protein?
Nucleotidase that shows the greatest phosphatase activity on purine (deoxy)nucleoside 5'-monophosphates, particularly the substrates 5'-GMP, 5'-AMP and 2'-deoxy-5'-AMP.
What are the official names of this protein?
5'-nucleotidase SurE 1, Nucleoside 5'-monophosphate phosphohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP1_SYNP6
Sequence: MIPIVVEESGRGERAFDIYSRLLRERIIFLGEPVTSDVANRIVAQLLFLEAEDPEKDIYLYINSPGGSVYDGLGIFDTMNHIRPDVSTVCVGLAASMGAFLLAAGAKGKRTSLAHSRIMIHQPLGGAQGQAKDIEIQANEILYIKQNLNEVLAERTGQPLSRIEDDTDRDFFMSASEAVEYGLIDRVIDRRALKATA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTG2_HUMAN
Sequence: MSHGKGTDMLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPSKGSGYRCIRINHKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSICVLYEEAPLAASCGLLTCKNQVLLGRSSPSKNYVMAVSS
What is the function of this protein?
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex.  Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner.  In vitro can inhibit deadenylase activity of CNOT7 and CNOT8.  Involved in cell cycle regulation.  Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity).  Modulates transcription regulation mediated by ESR1.  Involved in mitochondrial depolarization and neurite outgrowth.
What are the official names of this protein?
Protein BTG2, BTG family member 2, NGF-inducible anti-proliferative protein PC3.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: KDPC_ECODH
Sequence: MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIREGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARVAALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIAKYSQQPLVKYIGQPVVNIVELNLALDKLDE
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ASSY_CARHZ
Sequence: MAEKVVLAYSGGLDTSIIIPWLKENYGYEVIAMVADVGQGEELEPLREKAIKSGAAKIYIEDVKEEFVRDFVFPMLKAGAVYENKYLLGTSVARPLIAKKLVEIAEKEGAVAVAHGATGKGNDQVRFELTVKALNPDLKIIAPWREWEIKSREDAIDYAEKRGIPVPVTKKQPYSMDRNLWHLSHEGGILEDPAVEPPEDVLLLTNPPEKAPDQPEYVEIEFVKGEPVAVNGEKLSPVELIFKLNELGGKHGIGIADMVENRLVGMKSRGVYETPGGTILTFAHRELESLTLDRQTMHFKQMVALKYAELIYDGLWFTPLREALEAFVDKTQETVTGKVRVKLYKGNIYPAGITSPYSLYVKDLATFGEDNLYNQKDAEGFINLFGLPLKVRAMTQKPYQK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_OENVI
Sequence: EFESTILGPSVPDLVALTNEALSISITQKKSIIDTTTIRYALHRKTWDLEADRNLSPAKEHGTLFYQVGRAFAHTVLLRNCSIDPISIYIKKNLCEAGDSSLYKWYFELGTSMKKLTILLYLLTCSAGSIAQDLLSPPGPDEQNLITSYGLVENDSDLVHGLSDIVHGLLELEGALVGSSPTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEDEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEDEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEKDSSQFDNDRVTLLLRPKPRNPLDIQRLIYQHQKYESELEEDDDDDEDVFAPQKMLEDLFSELVWSPRIWHPWDFLLDCEAEIPAEEIPEEEDELPEDALETEVAVWGVEEEGEADDEEDVLLEAQQEDELLEEEDEELDEEEDELDEEEEEPKEEEDELHEEEEEEEEEEEEEDELQENDSEFFRVKPIIPRHRWIFRKKKDVFEVLSYPEEATEISKELLRLLNPKTKRDAPKRPRQRWWTKKKQDKHYELLLDRQRWLITKRSLSKSNGFFRSNTPSESYQYLSNLFLSNRRLLDQMTKTFFRKMAFPG
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: UBIE_COXB1
Sequence: MNETEKSTHFGYQTVPTDQKTDKVKHVFESVAAKYDLMNDLMSLGIHRWWKDFAITQCRLRTGQRILDLAGGTGDLAKRISPLVGDEGEVVIADINAAMLNVGRRRLLDQGIFRNIQFIQADAEKLPFPNNFFDRIVIGFGLRNVTNQLAALQSMHRVIKPGGFVVILEFSKPTLAPLKAVYDAYSFQLLPRLGKLVAKDEESYRYLVESIRMHPDQEALLSKMTDARFEDCDYHNLSGGIVAVHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: HXK_SCHMA
Sequence: MVFSDQQLFEKVVEILKPFDLSVVDYEEICDRMGESMRLGLQKSTNEKSSIKMFPSYVTKTPNGTETGNFLALDLGGTNYRVLSVTLEGKGKSPRIQERTYCIPAEKMSGSGTELFKYIAETLADFLENNGMKDKKFDLGFTFSFPCVQKGLTHATLVRWTKGFSADGVEGHNVAELLQTELDKRELNVKCVAVVNDTVGTLASCALEDPKCAVGLIVGTGTNVAYIEDSSKVELMDGVKEPEVVINTEWGAFGEKGELDCWRTQFDKSMDIDSLHPGKQLYEKMVSGMYLGELVRHIIVYLVEQKILFRGDLPERLKVRNSLLTRYLTDVERDPAHLLYNTHYMLTDDLHVPVVEPIDNRIVRYACEMVVKRAAYLAGAGIACILRRINRSEVTVGVDGSLYKFHPKFCERMTDMVDKLKPKNTRFCLRLSEDGSGKGAAAIAASCTRQN
What is the function of this protein?
Catalyzes the phosphorylation of various hexoses to hexose 6-phosphate.
What are the official names of this protein?
Hexokinase.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: BCAR3_RAT
Sequence: MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKKKGPPPIRSCDSASHMGTLPHSKSPRQSSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSFAEGRPDVVKRLSLTTGGIQARDHSLPRGNLLRNKDKSGSQPACLDHVQDRKAATLKAHQSESHLPIGCKLPPQSPSVDTSPCPNSPVFRTGSEPTLSPALVRRFSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPPSPSPWLNSEANYCELNPAFAVGCDRGAKLLSQALDSHEMLLTAKQNGASGPRNSGINYSILDGDDQGRHWDPLAVQTDEGQEDETKFVPPVMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDMKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKDTMGDLYSFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASSVSVPLLMPLVTLMERQAVTFEGTDMWEKNDESCEIMLSHLATARFMAEASESYRMNAERVLADFQPDEEMTEILKTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL
What is the function of this protein?
Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity).  Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (PubMed:24216110).  Promotes insulin-mediated membrane ruffling (PubMed:24216110).  In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1 (By similarity).  Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity (By similarity).  May inhibit TGFB/SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity).  Regulates EGF-induced DNA synthesis (By similarity).  Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling (By similarity).  Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA (By similarity).  Positively regulates integrin-induced tyrosine phosphorylation of BCAR1 (By similarity).  Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity).  However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity).
What are the official names of this protein?
Breast cancer anti-estrogen resistance protein 3 homolog, BCAR3 adapter protein, NSP family member, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, p130Cas-binding protein AND-34.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Localization to focal adhesions depends on interaction with PTPRA.