PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_VIBC3
Sequence: MANYFNTLNLREQLDQLGRCRFMAREEFATEADYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVSYALRQAAIDEQRQSFKNAKNNGFNVGSYEQLIPTADLVINLTPDKQHTSVVNAVMPLMKQGAALGYSHGFNIVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGWEIAKAWAAATGGHRAGCLASSFVAEVKSDLMGEQTILCGMLQAGSIVCYEKMVADGIDPGYAGKLLQFGWETITEALKFGGITHMMDRLSNPAKIKAFELSEELKDLMRPLYNKHMDDIISGHFSSTMMADWANDDKDLFGWRAETAETAFENYPTTDVKIAEQEYFDNGILMIAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANTVARKRLYEMNVVISDTAEYGNYLFANVAVPLLREKFMPKVGTDVIGKGLGVVSNQVDNATLIEVNSIIRNHPVEYIGEELRGYMKDMKRIAVGD
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NDHK_ORYSA
Sequence: MSLIEFPLLDQTSSNSVISTTLKDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDALTKLRKKISREIVEDRTLSQKKNRCFTTSHKLYVRRSTNTGTYEQELLYQSPSTLDISSETFFKSKSPVSSYKLVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FLGI_WIGBR
Sequence: MKYILIKLSIVMIFIINSASKAERIRDLTTIVGVRDNVLIGYGLVVGLDGTGDQTTQTPFTIQSLRNMLSQLGVSIPSGINMQLKNIAAVMVTAKLPPFVKIGQKIDVMVSSLGSAKSLRGGTLLITPLKGVDNQIYALAQGNILVSGFGAQSGGNTSQVNQLNGGRISEGAIIEKSIKTDFDKREIITLQLNNNDFSLAQQISDAINTYFGKKSAYPTDSRTINVILSASYDKSEKVKFIARLQNIPIIIGPSDAIIVINSRTGSVVINKEVMLNSCAVAHGELTVEIKKRTKVNQPNTILGGGSTVVTPETEILIKNQGDSLQEISSSTNLNEVISSLNSIGAKPNDLMAILESMKSAGCLNAKLEIN
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RL34_CERS5
Sequence: MKRTFQPSNLVRARRHGFRARMATKGGRLVLNARRAKGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GLK_SALPB
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVVRVYLDEHSVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGHVDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVKSDNRLPENLRPKDITERALADSCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKDYIHGIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_BURP0
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWSSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: KAD_BACC3
Sequence: MNLILMGLPGAGKGTQAEQIVAKYNIPHISTGDMFRAAMKAETEMGLQAKSFIDKGALVPDEVTIGIVRERLSQEDCVRGFLLDGFPRTVAQASALEEIMKDLGKKIDYVLNINVDSGLLLKRLTGRRICKECGATYHLEFNAPAKADVCDKCGGELYQRSDDNEETVANRLDVNIKQTKPLLDFYEELGYLQSINGEQDINKVFADIDVLIGGLA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_CAUVN
Sequence: MAERKQGGQGNGVGSSVVTEVKPKTQKPSLYRVLILNDDYTPMEFVVYVLERFFNKSREDATRIMLHVHQNGVGVCGVYTYEVAETKVAQVIDSARRHQHPLQCTMEKD
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PDXT_LEIXX
Sequence: MAGSPRVGVLALQGDVREHLTVLWALGADAVRVRRPDELETVAGLVIPGGESSVMDKLARTVGLAGPLRNAIAGGLPVYGTCAGLIMLADTIVDGIAGQRSLGGLDVAVRRNAFGSQAESFETDLSFPTLGAEPMHAVFIRAPIVESVGPRATVLARVPDGRVVAVEQDNLLGTAFHPELSGDKRFHEYFLVKVHGRV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: CH10_YERPP
Sequence: MKIRPLHDRVIVKRKEVESKSAGGIVLTGTAAGKSTRGEVLAVGNGRILDNGEIKPLDVKVGDVVIFNDGYGVKAEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_ONCMY
Sequence: MAHPSQLGFQDAASPVMEELLHFHDHALMIVLLISTLVLYIIVAMVSTKLTNMYILDSQEIEIVWTVLPAVILILIALPSLRILYLMDEINDPHLTIKAMGHQWYWSYEYTDYEDLGFDSYMVPTQDLVPGQFRLLETDHRMVVPVESPIRVLVSAEDVLHSWAVPSLGVKMDAVPGRLNQTAFIASRPGVFYGQCSEICGANHSFMPIVVEAVPLEHFEKWSTMMLEDA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LMBD2_XENLA
Sequence: MSGVALGIEIVSVFFLALFLLHRYGDFKKQHKLVIVGTLLAWYLCFLIVFIIPLDVSTTIYNRCVARHAVTPAPSNITVLSPTPGIVSNTTAQNHLPSADKLRSSDNSLEECSKPWSYIPRGIMPIFWRVVYWTSQFLTWILMPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGALLIYVAVNPNLHLEWYQLQTIGIAAANTWGLFLLVLLMGYGLVEIPRSQWNGAKKGYLLMKTYFKAAKLMTEKADAEETLEDVMEEVRKVNECIKYNHPLRKCVDTILKKCPAEYQEKMGRNMDDYEDFEEKNISYPSEKTLVKLHKQVIYAVQRHRRTQVQWSILLEQAFHLEDVAKNETSAAKQFVHTFPHQEPESWIMRRLYTPTIEWYWECLLRPWCSRILAVILALFSTVVVWSECTFFSAKPVLSLFAVFIQQAEQTHNYIYVEVVCFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDVSISHQNIEPTAYTSIMGSLRVLPLIADVFYIYYPMLVLILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLTDEGKELIKREKRKRQRLEDGETRRREWKERYPTNREDTSRNRSVNSDQKEPTYTEMTTNRSSKYTRASNRTERDRIELLQDAEPLDFNADTFNDDPLDSESGRYQPGGRYLSMSQSNSRIFDDV
What is the function of this protein?
May associate with G-protein coupled receptors and regulate downstream signaling pathways.
What are the official names of this protein?
G-protein coupled receptor-associated protein LMBRD2, LMBR1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYF_OENGL
Sequence: MKNTFSWIKKEITRSISLSLMIYIITRTSISNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDRQVKQVLANGKKGGLNVGAVLILPEGFELAPPARISPEMKERIGNPSFQSYRPTKKNILVIGPVPGQKYSEITFPILSPDPATNKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAAGIVSKIIRKEKGGYEITITDASDGRQVVDIIPSGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEVVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRP2_RHYMA
Sequence: APEESPKRAPSGFLGVR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 2, LemTRP 2.
What are the subcellular locations of this protein?
Secreted.
Protein: H2B2A_MELV
Sequence: MATQKETTRKRDKSVNFRLGLRNMLAQIHPDISVQTEALSELSNIAVFLGKKISHGAVTLLPEGTKTIKSSAVLLAAGDLYGKDLGRHAVGEMTKAVTRYGSAKESKEGSRSSKAKLQISVARSERLLREHGGCSRVSEGAAVALAAAIEYFMGEVLELAGNAARDSKKVRISVKHITLAIQNDAALFAVVGKGVFSGAGVSLISVPIPRKKARKTTEKEASSPKKKAAPKKKKAASKQKKSLSDKELAKLTKKELAKYEKEQGMSPGY
What is the function of this protein?
Histone-like protein that is recruited to viral factories during viral replication and participates in viral DNA packaging and virion production probably by forming unstable nucleosome-like particles (PubMed:34297924).  May compact the viral DNA (PubMed:34297924).
What are the official names of this protein?
Histone doublet H2B-H2A, Histone H2B-H2A fusion protein, MV-H2B-H2A.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Virion. Note=Localize to cytoplasmic viral factories after virus infection (PubMed:34297924). Also present in the nucleus but at much lower concentration (PubMed:34297924). The viral histones that localize in the nucleus apparently do not interact with host genomic DNA and can leave the nucleus to associate with the viral factory (PubMed:34297924).
Protein: UNG_RALSO
Sequence: MTRRADPAQATLFDDDEPAGAPTATGGFVPLADQFDALPADWKALLGPCLARTDWPALCAFVDGERAAGKPIFPTEVFHALHLTPVDAVRVIILGQDPYHGTGTVDGREVPQAHGLAFSVPAGVRVPPSLRNIYKEIEAEYGRKLSAGSGNLEGWAQQGVLLLNTVLTVEQGQAASHARRGWERITDCLLEHLARVGHARVFMLWGSHAQAKRALLPEGHLVLEAPHPSPLSAHRGFLGCGHFRAANDWLAAQGQSTIDWLRPQAD
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BURO1
Sequence: MTKKVYVKTFGCQMNEYDSDKMVDVLNAAEGLEKTDTPEDADIILFNTCSVREKAQEKVFSDLGRVRELKEAKPGLLIGVGGCVASQEGASIVSRAPYVDLVFGPQTLHRLPQMIDARRASGRAQVDITFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGDEVSRPLDDVLTEVAGLADQGVREVTLLGQNVNAYRGALTAGSTDIADFATLIEYVADIPGIERIRYTTSHPKEFTQRLIDTYAKVPKLVSHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPDLSLSTDMIVGFPGETEDDFDKMMALVHEMGYDTSFSFIYSPRPGTPAANLADDTPREVKLKRLQHLQATIEENVARISQSMVGKVERILVEGPSRKDPNELAGRTENNRVVNFPAPLASHPRLIGQMIDVKINHAYPHSLRGELVLVSDDASTATH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
Protein: Y164_METJA
Sequence: MRENMIKVVDGEYVKTLYEGNLEEIINEIDTGYILILVKEGNKLHEGYIFVEDGKIVGCYYTDSESTEVFGNKEKVIELLNYENKVIDIYKYNKDKINLMKWLYPEIFACKDTNKVSEKNEDMSEKRDIVEKYLNIKLDIPLDNLIEANTKDFEKYLEDNKYIIINAYRKKDGKFENGYIIYKGQTPIAAAYECDLGVLLGKDAYEKLEEMLKDENTVIDVYEYNEKKTHVILELYPQMKILDENENKSSEKADSLESEGSITTAEEIEEESTVSREELLKKLGIKEPDENWIETILEDVFRPSDEELEELKEKIESEIVNKVKRMEGVSDVLVNLKIKWENGRYYIFGDVNVKRKRILGIIKKDIDPSIVKFEIDNTIKKYVSKYTSRININIE
What are the official names of this protein?
Uncharacterized protein MJ0164.
Protein: RETST_RAT
Sequence: MWITALLLVVLLLVVVHRVYVGLFTGSSPNPFAEDVKRPPEPLVTDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAGGCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGPNGRKEFPMYSGRKEYIQGLKEKFPKEEAVIDKYMELVKVVAHGVSHAILLKFLPLPLTQLLNKFGLLTRFSPFCRASTQSLAEVLKQLGASPELQAVLSYILPTYGVTPSHTTFSLHALLVDHYIQGAYYPRRGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVSVKKGQELVNIYCPVVISNAGMFNTYQHLLPESVRYLPDVKKQLTMVKPGLSMLSIFICLKGTKEELKLQSTNYYVYFDTDMDKAMECYVSMPKEKAPEHIPLLFIPFPSSKDPTWEDRFPDRSTMTVLVPTAFEWFEEWQEEPKGKRGVDYETLKNTFREASMSVIMKLFPQLEGKVESVTGGSPLTNQYYLAAHRGATYGADHDLARLHPHAMASLRAQTPIPNLYLTGQDIFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVRAQKKKK
What is the function of this protein?
Catalyzes the saturation of all-trans-retinol to all-trans-13,14-dihydroretinol.  Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers.  May play a role in the metabolism of vitamin A.  Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP.  May play a role in adipocyte differentiation.
What are the official names of this protein?
All-trans-retinol 13,14-reductase, All-trans-13,14-dihydroretinol saturase, RetSat, PPAR-alpha-regulated and starvation-induced gene protein, RMT-7.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: ASTE_SHESA
Sequence: MLQALLDSKDFLALTLANPETLGDEFSFTLGEHTRVEVWNTGVIVFEPAQAQGKDVILSCGVHGNETAPIELCNTLIKQLLQQKIIAKQRTLFLIGNPLAINNGTRIIDENMNRLFSGEHSNPPGLVNPERVRAKKLEAYVDRFFKGAAAGRQRIHYDLHTAMRASKHEKFAIYPYRPGRAYSAEQIMFLAASGVDTVLFHHEPTTTFSYFSSEQYGADAFTIELGKVYPMGQNDMTRFIAAQEMFMRLITDKPLALEPFSADKVNLYQVCRVINKHFDDFEFTFAADVENFRSFPKGFVLAREGGQEIKVEQEFEAIVFPNAKVPIGNRTVICLIPSVAPDVR
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: NDS8B_ARATH
Sequence: MASLLARRSFSALRARHLAFSGQGLQGSHLCGLQSRAISYGSNKDDEEAEQLAKEISKDWSTVFERSMNTLFLTEMVRGLSLTLKYFFDPKVTINYPFEKGPLSPRFRGEHALRRYPTGEERCIACKLCEAVCPAQAITIEAEEREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLENGDRWETEIAENLRSESLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  May donate electrons to ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-B, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
Protein: AP3S1_HUMAN
Sequence: MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Clathrin-associated/assembly/adaptor protein, small 3, Sigma-3A-adaptin, Sigma3A-adaptin, Sigma-adaptin 3a.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: SRY_HORSE
Sequence: MSRVSNSDNYSLAGQQHTVLGSGRTSSLLWTSNPGSHFRSETRGNGRENGQDRVKRPMNAFMVWSRDHRRKVALENPQLQNSEISKRLGCQWKMLTEAEKLPFFEEAQRLRAMHQEKYPDYKYRPRRKAKMPQKSDKPLPQTPLLHCAGRRTYTSTSGCPFLIHGRLFLRATQSQTGGAVKPFAAGATAISALQQELSQQHRTLRCHSGNVGYADIRRRSLSL
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: CYSI_SHEAM
Sequence: MSQYPIKPELQVQGQLSDNERLKAESNHLRGTITTDLKDEITGGFTGDNFMLVRFHGMYQQDDRDLRAERAEQKLEPLHNVMLRARMPGGIIKPEQWLAIDEFAREHTMYGSIRLTTRQTFQFHGVFKPDIKPMHQMLNKIGIDSIATAGDVNRNVLCTSNPVESELHQQAYEWAAKISEHLLPKTRAYAEIWLGEEKVETTETEPVLGDSYLPRKFKTTVVIPPHNDVDVHANDLNFVAIAENGQLVGFNVLVGGGLAMTHGDKSTYPRRAEDLGFIGLEHVLKVAEHVVTVQRDYGDRVNRKNAKTKYTLDRIGVDAFKSEVEQRVGVAFGPSRPYEFTHRGDRFGWVEGIDGKHHLTLFIENGRLLDYPGKPLKTGVAEIAKVHKGDLRMTANQNLIIAGVAAEDKAQIEQLAREHGLLDNVTTQRKNSMACVSLPTCPLAMAEAERYLPTLVTHVEGILSKHGIADDHIILRVVGCPNGCGRAMLAEAGLVGRGPGKYNLYLGGNTAGTRIPKLYLDNVAEAEILAALDSLIGRWSVERNPGECFGDFVIRVGVVAEVKVSKTDFHA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: GLGC_THET8
Sequence: MVKVEVLGMILAGGQGSRLYPLTAKRAKPAVPFGAKYRIIDFVLNNFVNSGIYAIYVLTQYKAQSLTEHIQRYWRFGAFLEDHFILLVPAQMYRYEELGPVWYRGTADAIYQNLHLVHNHAPKAVAVFGGDHIFKMNIRHMVEYHYDTRADITIAAYPVPVAEATRFGVLQVDEEWRITEFQEKPEEPKPIPGRPDMALASMGNYIFRTEALFELLEADARDETSAHDFGKDVIPRALREGYRVYAYDFHRNPIPGQEGPNLYWRDVGTLDAYYEASMDLVKVVPEFDLFNPEWPLRTANLFSPPAKFVHETGERVGRALNSLLAGGVIVSGGTVRESVLFRRVRVNSYSLVERSVLFDDVEVGRYCRIRNAIIDKNVKIPPHTEIGYDLELDRARGFTVTPEGVVVVPKGYRF
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: THIE_CALBD
Sequence: MTKEGKLKLFSTYTIYGMTAEKFSNGRSNIEVVKVMLDSGIKIIQYREKYKSLKEKYKECLEIRKLTEDYEALLIVNDHADLCQMVGADGVHLGQEDLPADEVRKLLGDKFIIGVTTHTKDQVLKAKEDGADYVGLGPVFASFTKDNPHPPIGLEMVKWAAENSPLPFVAIGGIKEHNLKEVLASGARCICAVTEIVGADDIRKKIESLFKILKSFERS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.