PharMolix/UniProtQA huggingface dataset:
Protein: SNG2_RAT
Sequence: MESGAYGAANAGGSFDLRRYVSQPQVVTRLVSMVLALIVFSCIFGEGYINLHSSDQLHCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAATKPDDVLVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGVDAFIQNYVDPTPDPTTAYASYPSASVENYQQPPFTQNVETTEGYQPPPVY
What is the function of this protein?
May play a role in regulated exocytosis (PubMed:10383386).  In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles (PubMed:12928441, PubMed:15590695).  May also play a role in GLUT4 storage and transport to the plasma membrane (PubMed:26071524).
What are the official names of this protein?
Synaptogyrin-2, Cellugyrin.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes.
Protein: BCHB_CHLAA
Sequence: MRLAYWMYEGTAHHGVGRIANSMRNVHAVFHAPQGDDYVNAIFAMLDRTPNFPAMTTSVVSGTDLARGTIRLPDTLRQVEERVHPDLIVVVASCSTILLQENLEIAAQHAGLQCEVMVYDANPYRMQEIVAAESLFTDLVKRFAKPQPRTERPTVNILGPASLGFHARHDLISLRRMLKTLGLEVNVVAPWGASIADLRRLPAAWLTIAPYRELGLRAAIYLEEQFGVPALLDAPIGVQPTLRWIERLRELLAQAGADVPMPPLTAFSLDGMSAPSAVPWFARTADMDSFSGKPAFVFGDATHVVGVTRFLRDELGMPIAGAGTYVKHQADWVREQLTGYVDEVLVTDEFQVVADRIAALRPELVCGTQMERHTSRRYDLNCMVISPPTHIENHLLAYRPFLGFDGADVIADEVYTTCTLGMEKHLIDLFGDAGLDLPEKTERTPVAEPAPVAATVESPQPQNEPAIAVASAPSLTSAPATPTPAAVVDPVWAADAEAMLKKVPFFVRGRVRGNVEKYARQRGHAVITAEVLLAAKEELGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: SYGA_PELPD
Sequence: MTFQDLILSLQGYWAKQGCIIQQPYDTEKGAGTFNPATFLRVLGPEPWNVAYVEPSRRPTDGRYGENPNRLQHYYQFQVIMKPSPLNILDRYLDSLRAFGLDPCKHDIRFVEDDWESPTLGAWGLGWEVWLDGMEITQFTYFQQAGGIDLKPVSSEITYGCERIAMYLQGVDNVYDLEWVKGIKYGDIHHESEVEFSKYNFEEADVDMLLKLFGMYEKECLRLVERDLVLPAYDYVMKCSHAFNLLDARGAISVTERASYIGRVRNVARVCAEGYLRMRERLGFPLLKGGVA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_LEGPA
Sequence: MIVQDSVCSELMRGCEEILPVPELEKKLQKGIPLKIKAGFDPTAPDLHLGHTVLLNKLRQFQQFGHEVIFLIGDFTAMIGDPTGKNVTRMPLSQETVLENAKTYQHQVFKILDPDKTTVAFNSQWLNKFNAVDLIRLAATHTVARMLERDDFNKRYTTGQPIAIHEFLYPLLQGYDSVALKADVELGGTDQKFNLLMGRELQKHYGFEPQVVMMTPLIEGLDGVKKMSKSLDNYIGINETPEQIFGKIMSVSDELMWRYIDLLSFKTGKEIQQLKQSVLEGKNPRDVKIDFAKEIVARFHDQTQAELAHNNFIERFQKGNIPEDLEELSLVIVEPIALAQLLKQIDLTASTSESIRMVKQGAVKVDGDKISDPSLKLPIGKSYIIQVGKRRIAKLSIQQAD
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_ACTSZ
Sequence: MKHNIIELAQNLIRRPSVSPDDQGCQQMIAQRLEKLGFTIEWMPFNNTLNLWAKHGCGAPVIAFAGHTDVVPTGDKSQWVYPPFEAEIVDDMLYGRGAADMKGSLAAMVVAAEEYVKANPNHAGTIAFLITSDEEAAAKDGTVRVVETLMARGEKIDFCMVGEPSSSKTLGDIVKNGRRGSVTGNLYIEGVLGHVAYPHLAENPVHKALPFLQELTAYQWDNGNEFFPPTSLQIANIQAGTGSNNVIPGELYVQFNLRYCTEVTDEFIKNTVAEMLKKHGLAYRIEWNLSGKPFLTEPGKLVDAVVDSLESVAGVKPKLDTGGGTSDGRFIALMGAEVVELGPLNATIHKVDERVSVTDLVTLGAVYNQMLVNLLD
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: FTSK2_RALSO
Sequence: MARASTTPTTRTDPAALPSRIGRLLGEVRWFLLLAVTIAFLTILLSYNKADPGWSHASQVDDVRNLGGRVGAWFADVLLFVFGASAYWWALLLLRRVWRGWRELMSDERVPRAATPRVDAGVTWFGFALILSASMGLEAIRMHTLHMKLPRAPGGVLGDLIGGSLQHALGFTGGTLLLLLMFTVGLSLFFHFSWLNLAEQIGAGVETLFVGFKTRRENKQDRAIGEAAKVEREEVVETRRVRIEEAPPVQIVRPAAVVKSERVEREKQQPLFVDIQDSDLPALALLDAVPPAQETVSAETLEFTSRLIEKKLKDFGVEVTVVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSVRVVETIPGKNCMGLELPNPKRQAVRLAEILGSQVYNESASQLTMALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKARADAVRLILIDPKMLELSIYEGIPHLLCPVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIHNPFSLTPDAPEPLDKLPMIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSDDEVHRVVENLKSQGEPNYIEGLLEGGTADGEGGGDGFGGGAGLAGGGAGEADPLYDQAVDVVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK 2.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: PM2A_PHLSP
Sequence: SCQKWMWLCDEERKCCEDMVCKLWCK
What is the function of this protein?
Gating-modifier toxin that non-selectively inhibits voltage-gated sodium channel Nav by shifting the threshold for channel activation to more positive potentials.  This toxin moderately inhibits human Nav1. 2/SCN2A (IC(50)=404 nM), Nav1. 5/SCN5A (IC(50)=218 nM) and Nav1. 7/SCN9A (IC(50)=333 nM).  Inhibition of Nav1. 7 is voltage-dependent, with lower inhibition at more positive test pulses.
What are the official names of this protein?
Mu-theraphotoxin-Phlo2a, Mu-TRTX-Phlo2a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DUS_MYCTU
Sequence: MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: MATK_PHYPA
Sequence: MEKLKKNKKKLIWQQRFLYPLLFQNDFYALAYNHSLNKFNLKKIENSNLNKHFSFLTLKRLVKRIRRKRNIEELNKNYNKIFDINYNNYFYSKVIREGLAIILENFFLVQSKKKIVKKFTEWTNYQSIHTVFPFIEDNFLHSNYILNTKIPSLIHPELLIRILRRRIQDASFSHLLRLIFHKNKKLVTLNIFSQREITKLSIFLWHSYIYELEFFLVNQWKTLNYFKSLSYLISLNKTYCITKIQHVIKKPLDIKLQFFYKKKMSFHYVRYENHFIIAIKNSNFLAEKWKFFFYKFWQYYFYYLFKLSRINLKKISKNCFSFLGYVFGIQTKSIIVKSNMIHTLSKINISRKEIYSITPISSLIELLAKENFCDTLGHPISKLAWTTLTDDEIFNRFDQIWRNFFYYYSGCKNKKNLYQVQYILRFSCAKTLACKHKSTIRYVWKKYGSNFFAKSFFFKKQELISLKFFKLYPSIKKIWYLNILQINALAKLLQKKILKTNRLNI
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS21_STRR6
Sequence: MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVKRKRKSEVARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: QUEC_DESAP
Sequence: MKGIVLLSGGLDSAVCLAFGVRSLEVALCLTADYGQLAAGREIAAAAALSAHYGIRHQVVELPFLREIDCSALTGRLGLPEPEEMELDDPVRSAETARQVWVPNRNGLLVNVAACYAEALGCERIIAGFNREEAQHFPDNSPQFLDAVNHSLAYSTLSGIRVISYTQQLDKAEIVALGQRLGLPWSLVWSCYRGGDEACGVCESCRRLERAKRSAGGVRV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: GP38_BPMU
Sequence: MLKIKPAAGKAIRDPLTMKLLASEGEEKPRNSFWIRRLAAGDVVEVGSTENTADDTDAAPKKRSKSK
What is the function of this protein?
May possibly stop tail sheath polymerization by capping the polymerizing tail sheath once it has reached its requisite length and prevent its depolymerization.  Probably interacts with both the tube and sheath proteins.
What are the official names of this protein?
Putative sheath terminator protein, Gene product 38, gp38.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Tail.
Protein: CBID_GEOSM
Sequence: MSGKELRYGFTTGACAAAAVKAAAQMLRDQAMVREVELMLPCGIGANFQVHGGVLRDNTASCYVVKDAGDDPDVTNGAEIHVTASIEFFTKNEIKIEGGTGIGRVTKPGLAVPVGAWAINPVPRSMILEVVKEVFALRCIPATLTFSISIPNGEELAKRTLNERLGIVGGLSILGTTGIVKPISAKAWTDTVDASVDVALACGARTVVLATGRSSEIVAQKHLSLSEEAFVMMGDHFGYAMRSCASKGVPEVVVAGQFAKLVKIACGHEQTHVTSSQMDLDALAWWLREVPATAHLEQMAREANTARHLLEASGYNKALIELVCSRVLKVCADVAPWMKARVMLAGYHGDLLYFSP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: DACT3_HUMAN
Sequence: MIRAFSFPVSPERGRLRGWLEGSLAGLCELHWLRERQEYRVQQALRLAQPGMGGAEAEDEEDADEDEDAAAARRAAAALEEQLEALPGLVWDLGQQLGDLSLESGGLEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKKKILRFRSGSLKVMTTV
What is the function of this protein?
May be involved in regulation of intracellular signaling pathways during development.  Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.
What are the official names of this protein?
Dapper homolog 3, Antagonist of beta-catenin Dapper homolog 3, Arginine-rich region 1 protein, Dapper antagonist of catenin 3.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
Protein: NPS9_SERL9
Sequence: MAPGRVYPPSDKPIALLDLLHFHLVHNPYFPIYIFPNDDDTLTEISFLEFTRAVHRVAHIVRPNRSGQDGEIVALIANTDTLLYHAIGAGMILADIVPFYMSPRNSTPAVASMLQKTACNRIFTIPSVHESLISGLDGLGGPALQFQTIPTLAQVFPNLGKEKSHYPFEPYPEAAITPALDAVFLYLHSSGSTGYPKPIPLTNRCQLHWLQQPGILGYRHYLPDLCLGFAALPPFHSLGNCMQLYTPLISVITVALYAPTSFHDPTAPPVIPTSENILDNLRKTGANCIIVVPSFLEQWAWDEKAVETLKNMSLVLYGGGPLSSKVGDALCAAGVSLAVQYGTTEFGAPTQLPDKVQLENGLWEWMRFGLSVLIRWVHQGDETYECQLLTTEKYQMAVENMSDVKGYATSDLFVKHPTHEGLWKIIGRTDDVLTLASGEKTVPAMMEGIISSSAHVNGVIMFGRGRNQVGVLVEPRSAHVDLADNKAIEEFRNRIWYEVDEANKNAPTFSRIFKEMILITSPDKPMFRVGKGTTSKNATLKAYEEEIDALYRTVEASTKIGNSTAPPSEWTVSTLEHWLNEQATELALGTIVVPNIDLFAQGFDSLSATFLRNRIIGAMRSFPDLQLRAAARRIPHNLVFECPNIKLLADRVAKIAGQPQSQVNEQVKGSALHDAKMEIETMLGKYSAELRRTKKTNGSHVESSASTKAGRTVVLLTGSTGGLGSYLLASLLKNEEVAKVYALNRHSKASRVQQRQTAVFEDRELDVALLKLDKLIFIEADATAERCGLNEQTYDQLRQSVTVIIHSAWRVDFNLPLSSFEPNVRGTFQLVDLALSSTLHSTPRFLFISSVGSAQGWDRSRGAFPEDVQLDASVAVGSGYGASKYIAERLVTSSGLNATSLRLGQIAGGPNGAWTLSDWFPILVKSSLALGKFPNIQAYVSWMPAEKVSAAILDVALAKHAPPPALNIVHPHPVSWPDVLKPVRDAVVAKKRLPKESLPFVRMSEWVALLEMRAEEATESDINAIPAIKLLDWFRALAGVDEDLQRTGRTDVEVGGIVKMVTEKAQSISATLSGLSQIGQADAKLWVDYWIARGLF
What is the function of this protein?
Adenylate-forming reductase, a natural product biosynthesis enzyme that resembles non-ribosomal peptide synthetases, yet serves to modify one substrate, rather than to condense two or more building blocks.  The A-domain preferentially accepts L-threonine as substrate.  The natural product of the enzyme is not yet known.
What are the official names of this protein?
Adenylate-forming reductase Nps9, Nonribosomal peptide synthase-like enzyme 9, NRPS-like, Threonine reductase.
What is the protein family that this protein belongs to?
Belongs to the adenylate-forming reductase family.
Protein: KU_AGRVS
Sequence: MAPRRPYWRGYLKLSLVTCPVAMTPATSESEKVRFHTLNKDTGNRVVSHYVDSVTGKPVKDEQEAKGYERGENDYVLLTDEDLESVELETVRTIDIEKFIPRGSIEWVYLETPFYLTANDKIGDEAFAVIRQAMEAEDVVGVSRVVLGRRERAVVLEPRGEGIVVWTLRFGDEVRPESEYFTGIEKKSDAKGVSAVEAVIKKRMQDWSPEMVSDPIQESLLKLIADKKKAKKPSKAKASKSTKGDDEEKSNVVNIMDALKKSVAKELKSRKAG
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: PGK_DEIRA
Sequence: MTGLCPLHQPSPLDHPHSGGTPMQNLSQLDVKGKRVLVRVDYNVPVGDGVVQDDTRITASVPTIKKLLDGGASVVLMSHFGRPKNGPEDKYSLKPVAEAVSRALGQDVKFIPSLPGSDETLQAVQALRPGEVALLENVRFEAGEEKNDAALNDKLAKLGDAFVLDAFGSAHRAHSSVSGVAGKLPHAAGGLLQSEVDALGKLLHAPEHPYVVIIGGAKVSDKIKVIENLLPKVDRMLIGGGMMFTFIKARGGQIGNSLVEDDQLDLAKGLLEKYGDKLLLPTDAVAADKFAADAQSKVVPADQIPDGWMGLDIGPDTQRAYADALQGAKTVFWNGPMGVFEFDQFAAGTNAVAAAVGSLKDQAYTVVGGGDSVSAINKSGKADQIDHISTGGGASLELLEGKELPGVVAMA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_RHIME
Sequence: MTSFFDSESPSNVAEYSVSELSGSIKRTVEQAFEHVRVRGEISGYRGPHSSGHAYFALKDDRARIDAVVWKTTFARLKFRPEEGMEVIATGRVTTFPGSSKYQIVIDSLEPAGAGALMALIEERKRKLAAEGLFDAGRKRPLPFMPRVVGVVTSPTGAVIRDILHRIADRFPVHVIVWPVRVQGDGACEEIVAAIEGFNALQPGGSIPRPDVLIVARGGGSLEDLWCFNDEAMVRAAAASAIPLISAVGHETDWTLIDHAADQRAPTPTGAAEMAVPVKADLEAQLASLAARLKGAAARQMDNRRQTLRSLARALPSLDQLLALPRRRFDEAAAGLGRGLQMNTANKRRSFERNAAHLRPELLTARIVDRRQRVLDAVNRAERIVERKVQRGAQRISSADASLRVLPSRLIGQIHRASDRVSSLGRRGDAAIAADLRRMKSALAAQDRVLQSLSYHSVLQRGFALVRDAAGEPVKQAAAVHPGMALSLEFADGRIAAVAGEDGTAPQSPKKRPARSGEPTKQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_BURMS
Sequence: MTTVNLAAYRFVSLDSIEQWRPLVAARCNTLGLRGTILLAPEGINLFIAGPREATDAFVDYIRHDPLFEGKFADLPFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPSVDARTLKAWLDQGHDDAGRPVVMLDTRNAFEVDVGTFDRALDYRIDKFSEFPAVIEANRADLEGKTIVSFCTGGIRCEKAAIHMKDVGIENVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLAPTADVTCFACRAVVPADAQQSPLYVPGKCCPACHPGDSGTPGRRAEPGAEPARAV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: UVRC_HAES1
Sequence: MFDAKNFLANVTHQPGVYRMFDEKGQVIYVGKAKDLKKRLSSYFRTNLNSKKTSALVSHIHSIETTITASETEALLLEHNYIKAFQPRYNVLLRDDKSYPYILLTKERHPRITSHRGSKKVQGEYFGPYPHAGAVRETLSLLQKLFPIRQCENSVYNNRSRPCLQYQIGRCSGPCIDGLVSDEEYQQQVDFARLFLQGKDQQVLEHLIKKMEQASMQLNFEQAAYFRDQIQAIRAVIEKQFVSNERLDDMDILAIAYQLGIACVQVLFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRIIPSTIIVDHVLNEKHELEVLLTEQAGRKVNIQDNVKGNKSKFLHLAQMNAQAALVTQLKQANLIQERYQALQELLSLTTIKRMECFDISHTMGEQTIASCVVFDTEGPLKSDYRRFNISGITAGDDYAAMEQALLKRYDRPLENEKIPDIIFIDGGKGQLNRALQVFAQLNVSWDKNKPILIGVAKGVDRKAGLETLIISKQNKEVNLLPDSLALHLIQHIRDESHYHAIGGHRKKRQQAFTQSGLEAIEGVGAKRRQALLKYLGGMQGVKNATLAEISSVPGISAALAERIYETLRSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_ALKMQ
Sequence: MDAREIIKYIQESEKKTPVKVYIKGNLSEINWEQEGIKSFITGNTGVIFGEWKIVSKLMEANQKNIEDFVLENDRANSAIPLLDLKGIHARIEPGAIIREKVEIGNNAVIMMGASINIGAVIGEGTMIDMNVVVGGRGTIGKNCHIGAGAVIAGVIEPPSATPVIIEDDVVIGANAVVLEGIRVGKGSVVAAGAVVVQDVPPNVVVAGTPARVIKEIDEKTKSKTEIVKELRSLIEE
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: IDTG_CLAPA
Sequence: MAPSPIMPRYHVGPMASTRRAISKKGFPRTRSFPVLTAPLDYLRDSPGKDIRSGLTDAFNEFLCVPEDKVVTIKRIIDLLHNASLLIDDIQDDSKLRRGVPVAHSIFGIAQTINSANLAYFLAQQELKKLSNPDAFAIYTDELINLHRGQGMELHWRESLHCPTEEEYMRMVQNKTGGLFRLAIRLLQGESRSDRDYVPLVDTLGTLFQIRDDYQNLQSDVYSKNKGFCEDISEGKFSYPVIHSIRARPGDLRLLNILKQRSEDLMVKQYAVSYINSTGSFEFCRGKIDCLAQWANLQLAALEEAEGAGRGDKLRAVLRLLDMKASGKQADVAS
What is the function of this protein?
Geranylgeranyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of paspalitrems, indole-diterpene (IDT) mycotoxins that are potent tremorgens in mammals (PubMed:23468653, PubMed:29457197, PubMed:32077051).  The geranylgeranyl diphosphate (GGPP) synthase idtG is proposed to catalyze the first step in IDT biosynthesis via catalysis of a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyltransferase idtC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation of the two terminal alkenes of the geranylgeranyl moiety by the FAD-dependent monooxygenase idtM, and cyclization by the terpene cyclase idtB then leads to the production of paspaline (Probable).  The cytochrome P450 monooxygenase idtP then catalyzes oxidative elimination of the pendant methyl group at C-12 of paspaline and generates the C-10 ketone to yield 13-desoxypaxilline (PubMed:32077051).  The cytochrome P450 monooxygenase idtQ may catalyze the C-13 oxidation of 13-desoxypaxilline to afford paxilline (Probable).  Considering that both paspalicine and paxilline were detected in C. paspali, idtQ also catalyzes the formation of paspalinine from 13-desoxypaxilline via paspalicine as an intermediate (Probable).  Finally, the alpha-prenyltransferase idtF prenylates paspalinine at the C-20 or the C-21 positions to yield paspalitrems A and C, respectively (PubMed:32077051).  The hydroxylation of paspalitrem A at C-32 by a still unknown oxidase affords paspalitrem B (Probable).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase idtG, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, Indole-diterpene biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: KTHY_CUPPJ
Sequence: MRGKFITFEGIDGAGKSTHIGAVAARLRERKDIPAVVTTREPGGTPLGEDLRQILLHRKMHLETEALLMFAARREHIAEVIEPALARGDWVISDRFTDATFAYQGGGRGLATSRLETLETWVQDGLQPDLTLLFDVPLETASERLAGAREPDKFEAESRAFFERTRAEYLRRAAQAPERFRVIDATQSIEAIRVELEKIISTL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FLOA_OPITP
Sequence: MNLYLIFLIVVGVVGLVLVGLFLSFFSVWLRALLAGAPVSPFNLVAMRLRQVPYSVMVDARIRATKAGIKLSIDEIEAQYLAGGNVIACVHALIAAQKARIALDWQRACAIDLATKGSGKSVEEAVRTSVDPKVIDCPNPESGRTTIDGVAKDGIQVKVKARVTVRTNLDRFVGGAKEETIIARVGEGIVSTIGSAESYKVVLESPDAISKTVLHRGLDVGSAFEILSIDIADVDVGENVGAKLQEAQAQANKSIAQAQAEIRRAAAVALEQEMVARVQEMQAKVVEAQSQVPLAMAEAFRSGRLGVMDYFRMENIQGDTAMRNSLARPEDKKQ
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: RS21_STRPQ
Sequence: MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVKRKRKSEAARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS20_METNO
Sequence: MANTVSAKKMTRKIAKRTAINRSRRSRMRTFMRKVEEAIASGDAANALAALRSAEPEIMRASQKGIVHKNTASRKVSRLAARVKALQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.