PharMolix/UniProtQA huggingface dataset:
Protein: NOT1_XENLA
Sequence: MAGALCVTLLLLLSTNTVSGRKTWRRRGQQIVPSGRERSEGGDESFPLDFTAVEGNMDNFMAQIKSLAQSLYPCSAQRLDDEMKLHILHNKSVTCNDGSSAGYYLKESKGSRRWLVFLEGGWYCISHENCDLRYDTMRRLMSSKAWPPAKTASGILSTQPEENPHWWNANMVFIPYCSSDVWSGASPKTEKSGYAFMGSLIIQEVVKELLGKGLDAAKVLLLAGSSAGGTGVLLNVDLVADLLEELGYPGIQVRGLSDSGWFLDNKQYRRTDCTDIITCAPTEAIQRGIRYWSSMVPERCKQQFKEGEEWNCFFGYKIYPTLRSPVFVVQWLFDEAQLTVDNVHLSGQPVQESQWLYIQNLGRELRNTLKDVGASFAPACLAHEVITRSHWTEIQVRGTSLPRALHCWDRRLQETNKNSKVPLKGCPFHLMDSCPWPQCNPTCPSIRDHFTGQEMSVVQFLMHLGFDVQKMASQQGMEPGKLLGVLSS
What is the function of this protein?
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins.  Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.  Functions in the prospective ectoderm and is required for neural induction.
What are the official names of this protein?
Palmitoleoyl-protein carboxylesterase notum1.
What is the protein family that this protein belongs to?
Belongs to the pectinacetylesterase family. Notum subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SIK1_ORYSJ
Sequence: MAAARAPWLWWWVVVVVGVAVAEAASGGGGGGDGEGKALMGVKAGFGNAANALVDWDGGADHCAWRGVTCDNASFAVLALNLSNLNLGGEISPAIGELKNLQFVDLKGNKLTGQIPDEIGDCISLKYLDLSGNLLYGDIPFSISKLKQLEELILKNNQLTGPIPSTLSQIPNLKTLDLAQNQLTGDIPRLIYWNEVLQYLGLRGNSLTGTLSPDMCQLTGLWYFDVRGNNLTGTIPESIGNCTSFEILDISYNQISGEIPYNIGFLQVATLSLQGNRLTGKIPDVIGLMQALAVLDLSENELVGPIPSILGNLSYTGKLYLHGNKLTGVIPPELGNMSKLSYLQLNDNELVGTIPAELGKLEELFELNLANNNLQGPIPANISSCTALNKFNVYGNKLNGSIPAGFQKLESLTYLNLSSNNFKGNIPSELGHIINLDTLDLSYNEFSGPVPATIGDLEHLLELNLSKNHLDGPVPAEFGNLRSVQVIDMSNNNLSGSLPEELGQLQNLDSLILNNNNLVGEIPAQLANCFSLNNLNLSYNNLSGHVPMAKNFSKFPMESFLGNPLLHVYCQDSSCGHSHGQRVNISKTAIACIILGFIILLCVLLLAIYKTNQPQPLVKGSDKPVQGPPKLVVLQMDMAIHTYEDIMRLTENLSEKYIIGYGASSTVYKCELKSGKAIAVKRLYSQYNHSLREFETELETIGSIRHRNLVSLHGFSLSPHGNLLFYDYMENGSLWDLLHGPSKKVKLNWDTRLRIAVGAAQGLAYLHHDCNPRIIHRDVKSSNILLDENFEAHLSDFGIAKCVPSAKSHASTYVLGTIGYIDPEYARTSRLNEKSDVYSFGIVLLELLTGKKAVDNESNLHQLILSKADDNTVMEAVDSEVSVTCTDMGLVRKAFQLALLCTKRHPSDRPTMHEVARVLLSLLPASAMTTPKTVDYSRLLASTTTAADMRGHDVTDIGDNSSSDEQWFVRFGEVISKHTM
What is the function of this protein?
Receptor kinase involved in salt drought stress responses (PubMed:20128882).  Acts as positive regulator of salt and drought tolerance (PubMed:20128882).  May promote salt and drought tolerance through the induction of the activities of antioxidative enzymes, such as peroxidase, superoxide dismutase and catalase (PubMed:20128882).  May be involved in the control of stomatal development in leaf epidermis (PubMed:20128882).  Possesses kinase activity in vitro (PubMed:20128882).  Does not seem to be involved in heat tolerance (PubMed:26280413).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase SIK1, ERECTA homolog 2, ER homolog 2, OsER2, Stress-induced protein kinase 1, OsSIK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSMF_ECOLC
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGVAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCMWLKETYPDAVEFLPLGELFPAANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKDREAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALATPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_MESH2
Sequence: MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFLSFDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKKITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLILDKEISRAKLVDLLYIIEKKSIWEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIKLLEDFLSNKSKIRKG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: T106B_DANRE
Sequence: MGKALSHVAKHTCHDECQDSLTSSPGYSAMQTDDSKSGGDVSQFPYVEFTGRDSVTCPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVILCLLLCTLAVFFLFPRSIDVNYVGVKSVYVSYDQSKRIVYLNVTNSLNITNNNYYSVDVANITARVQFSQTVIGKTRISNITTIGPLDMKQIDYMVPTTIADEMSYMYDYCTLQSIKVHNIVVMMQITVTTVYFGHAEQVSQEMYQYVDCGGNTTALHEYSLNTPLTG
What is the function of this protein?
In neurons, involved in the transport of late endosomes/lysosomes (By similarity).  May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (By similarity).  May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6 (By similarity).  In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment (By similarity).  It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is particularly important in the sorting of lysosomes in axons or in dendrites (By similarity).  In neurons, may also play a role in the regulation of lysosomal size and responsiveness to stress (By similarity).  Required for proper lysosomal acidification (By similarity).
What are the official names of this protein?
Transmembrane protein 106B.
What is the protein family that this protein belongs to?
Belongs to the TMEM106 family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein.
Protein: PORCN_CAEBR
Sequence: MDHHLDPNLDNLFEMYGESVEECATQVANGTLLTLLQMLVLVWMFFLVWRLSLPPRIQTFLHIAMTTLTVAWFSPKKLESVMIFHTFSLISLFCAVQKLNGYRILGLNIMLLIALQNICSRANADDYFLTLRGVLMMHIMRLSTASFAIVDSNVRSISFDQLTLYLEYIYFPPFIIFGPYVTFDQFVKMREKKWTRFEEQLGVFVQGSVLIFIGITLAIISSCYVDFFEPGSQFVEDALTAMSFRCSHYFICLSTQAFAMFLGSKIVVANPVNIEFSRSTLQTVSEWNRPFHTYLHENIFKRRFFQSTALNVLLTFAVSALLHARDYQMWLTLLALGFIAYSETVFRKRIADRFSMCVAAKPCSVRANRRICKHKHASFSKRVLIINLFFMILSMYHLVFTGMTFTDDYAAIGYPFSHTWTIWGTHYYSSFIVSFAFLALSKII
What is the function of this protein?
Key regulator of the Wnt signaling pathway that mediates lipid modification of Wnt proteins.  Acts as a protein-serine O-palmitoleoyltransferase that catalyzes the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins.  Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.  Has a role in cell specification, specifically in blastomere signaling.  Involved in cytosketetal polarity.  Required for the orientation of mitotic spindle axis.
What are the official names of this protein?
Protein-serine O-palmitoleoyltransferase porcupine, More of ms protein 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Porcupine subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TADA_STRP3
Sequence: MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAKHLIKEQSDPFD
What is the function of this protein?
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
What are the official names of this protein?
tRNA-specific adenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: CAS2_FILAD
Sequence: MRIIVFFDLPTITLEDKRDYRDFRKFLIKKGFLMMQESVYCKLVLNQTVASSVLSSIRKHKPKSGLVQMIMVTEKQFAKMEYLCGEKRSNVVDSDDRLVIL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: FRDD_VIBC1
Sequence: MKPNYSVNTAPKRSDEPIWWGLFGAGGTWFAMITPITVLVLGILVPLGVIDAEAMSYERVSEFATSIIGALFIIGTLALPMWHAMHRVHHGMHDLKFHTGVVGKIACYAFAGLISALAVVFIFMI
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SODM_BACCA
Sequence: MPFELPALPYPYDALEPHIDKETMNIHHTKHHNTYVTNLNAALEGHPDLQNKSLEELLSNLEALPESIRTAVRNNGGGHANHSLFWTILSPNGGGEPTGELAEAINKKFGSFTAFKDEFSKAAAGRFGSGWAWLVVNNGELEITSTPNQDSPIMEGKTPILGLDVWEHAYYLKYQNRRPEYIAAFWNIVNWDEVAKRYSEAKAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: RL6_CUPPJ
Sequence: MSRVGKAPIALPKGAEVNVAAGVLSVKGPLGTLSQPIHSLVKVNVENDTLTFAPADESREANALQGTMRALAANMVKGVTTGFERKLNLVGVGYRAQLQGAALKLQLGFSHDVIHEMPEGVKAETPTQTEIIIKGADKQKVGQVAAEVRAYRPPEPYKGKGVRYSDERVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL1_ANAMF
Sequence: MSGDGSCSYSAEEGIRELLQSAKAKFRESVDVAIKLSVADSKSGESIRGAVVLPKGLGREVRVAVFAKGEHAKQASSAGADVVGDEELIEEIKKGRRLDVDWCIATPDFMPQISAIAKILGPRGLMPNPKFGTVTLELAKMVGIIKSGQVKFKSDRYGIVHVKIGDIGFTPEDLLENFNAVVAAVQGLRPTTIKGSYVRGVFVNSTMGRSFRIAGIG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y1429_DESPS
Sequence: MDISKLMQQAKDMQGKMAAIQEDLAKKIITGSAGGGMVEVQVNGQGEILAIKIEDALINTDEKEMLQDLVTAATNDGLRRAKDLSKQEMGQLTGGMNLPDLTNFLS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein DP1429.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y566_MYCTO
Sequence: MADSSFDIVSKVDRQEVDNALNQAAKELATRFDFRGTDTKIAWKGDEAVELTSSTEERVKAAVDVFKEKLIRRDISLKAFEAGEPQASGKTYKVTGALKQGISSENAKKITKLIRDAGPKNVKTQIQGDEVRVTSKKRDDLQAVIAMLKKADLDVALQFVNYR
What are the official names of this protein?
UPF0234 protein MT0592.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ENTP3_HUMAN
Sequence: MFTVLTRQPCEQAGLKALYRTPTIIALVVLLVSIVVLVSITVIQIHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSFSLDTFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFLAYLCSATRRKRHSEHAFDHAVDSD
What is the function of this protein?
Has a threefold preference for the hydrolysis of ATP over ADP.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 3, NTPDase 3, CD39 antigen-like 3, Ecto-ATP diphosphohydrolase 3, Ecto-ATPDase 3, Ecto-ATPase 3, Ecto-apyrase 3, HB6.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPF_ARCFU
Sequence: MRIAFTKMHGNGNDFVLIDEFEGVIVGEEEKPRFVRAVCHRNFGVGADGALFVQPSQKADVRFRYFNSDGSEAAMCGNGIRCFSRYVVEEGYAGERLRVETLAGILELEVKRENGWWVKVDMGKPKFGREEIPAKTDVWGYEVEHDGRKFRIYAANTGVPHVAVFVDSLDFDIVPLARKIRYSEIFPEGTNVNFAKVDGDTITVRTYERGVEGETLSCGTGSVAVAAIANRLGLTGSKVDVVTKGGLLKIELTEDTAYMTGGASRVFDGILRLNELRYDI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRX_YEAST
Sequence: MSASTTSLEEYQKTFLELGLECKALRFGSFKLNSGRQSPYFFNLSLFNSGKLLANLATAYATAIIQSELKFDVIFGPAYKGIPLAAIVCVKLAEIGGTKFQGIQYAFNRKKVKDHGEGGIIVGASLEDKRVLIIDDVMTAGTAINEAFEIISIAQGRVVGCIVALDRQEVIHESDPERTSATQSVSKRYNVPVLSIVSLTQVVQFMGNRLSPEQKSAIENYRKAYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase 2, OPRT 2, OPRTase 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: UVRC_CHLTR
Sequence: MRIEDFSLKDVSSSPGVYLMKDSQGTVLYVGKAKNLRNRLSSYLQKKGDSRKRIPFLMKKTTDIDTIVVSNETEAILLENNLIKKYQPRYNVLLKDDKTFFCLSVSLEHPWPRIEAIRTRALSPGKKKQWLFGPYVSAEACYALLEVISLWFPLRTCSDREFSTRQRPCVLYEMKRCLAPCVGLCSQTEYQETLDKAVLFLKGDVRSTISNLEKAIEKASQEQKFEHAAALYRTLTLIRQTMAKQHVEKFQAYDIDVLGLYRKGSLAIVSVLSVYSGKLLGARYFIFPENAQEDSALFSSFILQYYAENPRIPKEIFVPVSLDSPELPYLLNTAEPPKIRCPKTEYGKELLALAHKNAAEQAKPFNSITPPYEELQHFFNLSQYPYRIECYDNAHLQGEHNVGVCIVFENGLFSPKQYRTFSITSHGDDLAAFEEVLTRRFRSLTTELPNLIVIDGGRNQFKRAQRILEELNLTGITVVTIAKESGNHSKSLRQEKLFCETFPQGILLHPTSAILQFFQLLRDEAHRFAIQHYRKKHAKAVLTTKKIPGIGEVKTKRLLQKFKSWKRVFIASEEELKTVQGITAKDIQRIQEEGAKPE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_BRUA4
Sequence: MSETYVLKADLRTRVGKGSSRELRRNGQIPAVIYGDKQEPLAIAVSYKEIFYKIHGGGFKTTVATIEVDGKKIQVLPKDYQLDPVRDFPQHVDFLRVSAKSVVHVNVPVHFKNEEAAPGIKRGGVLNIVRHDVELIVPANAIPEALEFDLTGLEIGDSVHISAIKLPKGVTAAIQDRDFTIATIAAPAGLKSEEAASEGAAEEEAKDGE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SPN1_DROME
Sequence: MESSFQELYKKGLDIGEQQKQRQKELLKQQKLRRQQEQDDYRPLQNQEKPVPRKKSGKRSGHQKGIPYRPQLSEWLRHKPDDLNEWLLVPCPVGKRCLVVASKGITKAYSKGGWMFVNFRSSLPGDWQLQKGETILDCVYVEDADTFYVLDAISFGLQEVQECEASFRFYWLRARFEEHDYDKISENNEKKFKLLDHFDFEDPSAVEQALHKYPFFPENKPDLDGFLFYHKEASYVCRETPLVCWLFPFMMEDVLGLPVNKCYKAPEDYQPSHVLQYMDAFEQKLAEHRRTLKEQKKKVNEQKEDPHTMEAEEDVESDEYDSLKRVLDQQRRLELGEFDMDCAEPPSADGC
What is the function of this protein?
Functions as an U snRNP-specific nuclear import adapter.  Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs.  Binds specifically to the terminal m3G-cap U snRNAs.
What are the official names of this protein?
Snurportin-1.
What is the protein family that this protein belongs to?
Belongs to the snurportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus speckle. Nucleus, Cajal body. Note=Mostly localized to the nuclear periphery. In Malpighian tubule cells, detected in nuclear foci that include the Cajal bodies. Accumulates in the U bodies of the follicle and nurse cells.
Protein: MENG_CLAMS
Sequence: MMRADLSKKPGQVSAMFDEVSSAYDRTNTLLSVGNDQLWRVATTRAVAPVAGERILDLAAGTGTSSAALAASGAHVVAADFSEGMLEVGRRRLAGDDRVEFVHADATDLPFDDDSFDAVTISFGLRNVVEPRKGLDELLRVLKPGGRIVICEFSTPPVPLVRRGYDLYMKAVAPSLVKLVSSNASAYEYLNESIQAWPDQETLSSWLRAAGFASVEHRNLTAGIVALHRGVKPAGRHAAPRPAAS
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: GPI1_YEAST
Sequence: MPNYIFWPYESLFENSAAQGPQVALAISFEKTHFVVLGVCEPQYLEEVSIRPPYSVVATKNNGAEGWNYKVADPCNVHFRIPKLKFMQFYSSDPISLIIPEKEVGLHSSVGETLNYSKLEQHPRYKRDNKKLSETLNIINLFPAYCKALNELYPFIQTSQENLRGTMLNSVAAWCSSTCIYKMVAKIGFYLTFVICSIASLVSSLLNYSHFQLVNYSAFVQQIDLRCQQICYFPVQYERINKKDNIQNVGSMVEKDNSNSQFSHSYMPSKFYPDYILLYNTIWLIINDISFGLILGAILIENRDFLVSASHRVLKFFLYDSLKTITETLANNPLGIKLNAELANFLSELFLWVIEFSYTTFIKRLIDPKTLSSLLTLTIYMMFLVGFSFAVSLAIDFFAILSFPIYVFYRISSKLYHCQLNIMASLFNLFCGKKRNVLRNRIDHNYFQLDQLLLGTLLFIILVFLTPTVMAFYMSYTVLRMLTITIEIFSEAVIALINHFPLFALLLRLKDPKRLPGGISIELKTTVSNKHTTLELQNNPIKFKSMFRPYNLLLSQMRTNYFSFATVRKIVRGESIMVNRNKLYYVLYSSLPSKPLSVKDLYKRLTIQA
What is the function of this protein?
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1, GPI-GlcNAc transferase complex subunit GPI1, GPI-GnT subunit GPI1.
What is the protein family that this protein belongs to?
Belongs to the PIGQ family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FAR5_PRAMA
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SP110_YEAS1
Sequence: MDEASHLPNGSLKNMEFTPVGFIKSKRNTTQTQVVSPTKVPNANNGDENEGPVKKRQRRSIDDTIDSTRLFSEASQFDDSFPEIKANIPPSPRSGNVDKSRKRNLIDDLKKDVPMSQPLKEQEVREHQMKKERFDRALESKLLGKRHITYANSDISNKELYINEIKSLKHEIKELRKEKNDTLNNYDTLEEETDDLKNRLQALEKELDAKNKIVNSRKVDDHSGCIEEREQMERKLAELERKLKTVKDQVLELENNSDVQSLKLRSKEDELKNLMNELNELKSNAEEKDTQLEFKKNELRKRTNELNELKIKSDEMDLQLKQKQNESKRLKDELNELETKFRENGSQSSAKENELKMLKNKIAELEEEISTKNSQLIAKEGKLASLMAQLTQLESKLNQRDSQLGSREEELKKTNDKLQKDIRIAREETVSKDERITDLQKKVKQLENDLFVIKKTHSESKTITDNELESKDKLIKILENDLKVAQEKYSKMEKELKEREFNYKISESKLEDEKTTLNEKISNLAAENSQLKNKIEDNSTATHHMKENYEKQLESLRKDIEEYKESAKDSEDKIEELKIRIAENSAKVSEKRSKDIKQKDEQISDLTQNLKLQEDEISSLKSIIDRYKKDFNQLKSEQSNIQHDLNLQILNLENKLIESEDELKSLRDSQKIEIENWKRKYNNLSLENDRLLTEKESASDKEREISILNRKLDEMDKEKWNLQESKEKYKRELQKVITANDRLRREKEELNENSNNIRIMEDKMTRIKKNYLSEITSLQEENRRLEERLILNERRKDNDSTMQLNDIISYYKLKYHSEVRHNNDLKVINDYLNKVLALGTRRLRLDTRKGEHSLNISLPDDDELDRDYYNSHVYTRYHDYEYPLRFNLNRRGPYFERRLSFKTVALLVLACVRMKRIAFYRRSDDNRLRILRDRIESSSGRISW
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Potential role in cross-linking filaments or anchoring other molecules.  It is essential for growth (By similarity).
What are the official names of this protein?
Spindle pole body component 110, Extragenic suppressor of CMD1-1 mutant protein 1, Nuclear filament-related protein 1, Spindle pole body spacer protein SPC110.
What is the protein family that this protein belongs to?
Belongs to the SPC110 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Tightly associated with the nucleus. It is present in a granular pattern that excludes the nucleolus.
Protein: CL401_COCLU
Sequence: MKYSLIAALPALAAASPTFSTETIHKQSAPVLSSTSAKEVPNSYMVVFKKHVKDASKHHDWVQSVHSKNTQERMELRKRSSDLPVSNEVFAGLKHTYELSGLKGYSGHFDDETLEAIRNHPDVDYIERDSEVRILGGDEPETENNSPWGLARISHRDSLSFGTWNKYLYAADGGEGVDVYVIDTGTNVDHVDFEGRAKWGKTIPNGDADEDGNGHGTHCSGTVAGKKYGVAKKAHVYAVKVLRSNGSGTMSDVVKGVEFAAKSHSEAVSAAKNGKKKGFKGSTANMSLGGGKSTTLDMAVNAAVDAGLHFAVAAGNDNADSCNYSPAAAENAVTVGASTLLDERAYFSNYGKCNDIFAPGLNILSTWIGSKHATNTISGTSMASPHIAGLLAYMLSLQPAKDSAYAVADITPKKLKANLIAIGTVGALSDVPSNTANVLAWNGGGSSNYTDIIEKGGYTVKKAASKEEEKESEFRITIPSLSELEDDFEKAKESAGRKAHHVGGKL
What is the function of this protein?
Serine protease.
What are the official names of this protein?
Subtilisin-like serine protease Cur l 4.0101, Subtilisin-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: LPXC_PSEPF
Sequence: MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFRRADLDPVVEIPARAANVGETTMSTTLVNGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLEEQDAAKKFIRILREVTVEDGDKRATFVPFEGFKVSFEIDFDHPVFRDRTQSASVDFSSTSFVKEVSRARTFGFMSDIEYLRKHNLALGGSVENAIVVDADGVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFKGFKSGHALNNQLLRKLIEQKDAWEVVTFEDASTAPISYMRPVAAV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RS16_NEIMF
Sequence: MVVIRLARGGSKHRPFYNVIVTDSRSRRDGRFIERVGFYNPVANEKQERVRLNADRLNHWIAQGAQVSDSVAKLIKEQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.