PharMolix/UniProtQA huggingface dataset:
Protein: OAM_ASCSU
Sequence: MQGTDNAPPGAQANKSSSPRRIRHVRRHYTSNDHRHTPSTAESNPVQRIRSGEECTVELSMSPGQPLVEEQPLVEERPPVEEQPLVEEQPLVEEQPLVEEQPLVEEQPLVEGQPLVEEQPLVEGQPPVEGQPLVEEQPLVEGQPLVEGQPLVEGQPLVEGQPLVGGQPLVGGQPLVEGQPLVEGQPPVKVQPLVEGQPLGNMVSLYDQLPRGSILSLQKGLTLAGVTTPVDMPPLAGVILLCAVLPLASVIPPASATPFAAVIPPAAVIPLPGFLPLGRLLHLADLLLRAGVLLLAGILPLAGAPPLAGVPPLAVALPLAGAPPLAGVPPLAGAPPLAGALPRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRAGVLRRADVLRRADVVLLAGVQQLADVQRLADVQRLADVQRLADVQRLADVQRLVCVTPLSVVSPLAAVIPAVAVIPVVAVIRVAAVIMLEKMQPQGSSPQLQMGCRRIRQRRSSPRTCQKLRQERDRAGISWREHVGRHMLCSSTRSRYCSHRLGAACRSHCRLRCGVLCLPHALTQPTRQERGVAEMMSTS
What are the official names of this protein?
Ovarian abundant message protein, Protein OAM.
Protein: JIP5_ASPNC
Sequence: MFDTVCTLPLSADLFSQALHPKEPVVSVGLSSGHVQTFRLPTDEAASDDDETSNASSRNGRGHIDTMWRTRRHKGSCRCLTFGIDGETLYSAGTDGLIKAAKAETGVVENKIAIPTEKNGSIDAPTIIHALSPQTLLLATDSSALHLYDLRIPYSKVSAKPEQSHHPHDDYVSSLTPLPASDTSTSGFSKQWVTTGGTTLAVTDLRRGVLVRSEDQEEELISSTYIGGLAASGTSRGEKVLVGGSGGVLTLWEKGAWDDQDERIYVERGGGGGESLETMAVLPDELGKGKVVAVGLGNGRVKFVRIGANKVAAEVMHDETEGVIGLGFDVEGRMVTGGGQVVKVWHEAVVGADRYGAMPGEKRMYGDSDDSDEGDDSDDDSDDSDAGGRQDKPQNKRKKTKAKGKGGQQIMAFHDLDSMESSVVY
What are the official names of this protein?
WD repeat-containing protein jip5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYV_THIDA
Sequence: MELAKSFEPAEIEKRWYARWESAGYFKARDKPDAPAYCIMLPPPNVTGTLHMGHAFQHTLMDALTRYHRMSGDNTLWQPGTDHAGIATQIVVERQLDAQNISRHDLGREKFLEKVWEWKAHSGSTITRQMRRLGTSPDWSRERFTMDAGLSKAVTEVFVRLYREGLIYRGKRLVNWDPVLGTAVSDLEVVSTEEDGFIWEINYPLEDGSGHLTVATTRPETLLGDTAVAVHPEDERYAHLIGKHVRLPIAERSIPVIADEYVDREFGTGVVKITPAHDFNDWQVGQRHKLMAISVLTLDAKMNELCPTEYQGLDRYDARQTLLDALQAKGLLVSAKPHKLMIPRGDRTHAVLEPMLTDQWFMSMEGLAKQGLAAVDSGELKFVPENWTTTYRQWLENIQDWCVSRQLWWGHRIPAWYDADGEFYVAHTEEEARKQAGGRELTQDNDVLDTWFSSALWPFSTLGWPEQTPELERYLPTSVLVTGFDIIFFWVARMVMMSKHLTGKVPFREVYVTGLVRDSEGQKMSKSKGNVLDPIDLIDGIAVGDLVAKRTQGLMNPKQAASIEKRTRKEFPDGIAAYGTDALRFTFASLATHGRDIKFDLQRAEGYRNFCNKLWNATRFALMNLEGHDCGQEADQPMDFSDADRWIAARLQQAIGDVHEAFAAYRFDQAARAVYEFVWDEYCDWYLELAKVQLNHGTPEQQRATRRTLATVLETTLRLAHPIIPFITEELWQKVAPLAGVHGDSIMLSAYPQVDEAQRHPGSVARMQLLKELVNACRTLRGEMNLSPAQRVPLVIEGDAAVINTLAPYMVALGKLGEVSAVTALPEADAPVALVGDMRMMLVVEIDKDAERARLAKEIARIQGEIRKAETKLANPSFVDKAPAAVVQQEQARLADFAAMLQKLEAQHARLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_ECOBW
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RAB18_MOUSE
Sequence: MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREESRGGGACGGYCSVL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts (By similarity).  Also required for maintaining endoplasmic reticulum structure (By similarity).  Plays a role in apical endocytosis/recycling (PubMed:7706395).  Plays a key role in eye and brain development and neurodegeneration (By similarity).
What are the official names of this protein?
Ras-related protein Rab-18.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Apical cell membrane. Lipid droplet.
Protein: INCEA_XENLA
Sequence: MNDAECLSHLLQVCARKTEEFVRTLDSKHMVWLLEIEEEARKMFSSDFNAEPELMPKTPSQKRRRKKRTSILPDENRDPSGRRISRRQSNASWSSSVRRLSVRNQNKANDDSIQEEPAQLKRMTRARAQASIKSTPVLETALPESPSQICQKNAQVKISEQERRSAEQKLIESDFELKTVPEITKDNVSETVNSAVPAVPVTPENKSRAAGKLKIAASSTPEQKAEMVDLTCESPRPANEQQLNLSNQSATPTGSKSDRRSVRRSLVVRKSSSRRASLASQFSLASKRESMTREAVRKSIRQSISQKKAAMEISSTSSQRSYQSSIEMVDDEITIKIRPETVPSETVSEEAPAAESPRRSLRSRAFKKIAISNLPDSEEPPRKVTRQMVAGNAEPTPETTEDAQNIRRKSYKRAVDELSDDERPSEEERSPPRKKTPSPPCPPSKIVRPPPHMKSFLHTVQKNQLLMMTPGSIGKNIIMKSFIKRNTPLKTDPKTEEKERQRLDALRKKEEAELQRKQKIEEGKKRKQEELKVRREERLRKVLQARERVEQLEEEKKKKIEQKFAQIDEKSEKVREDRMAEEKAKKKMTAKKQEEVECRRKQEEEARRLKVKQMEEEERRHQELLQKKREEEELERQKKIAEAKRLAEQERERQLLAEKERLRAEREKERIEKEKALQLQRELERAAQEKEQQRREAEERKKREQQERLEQERLRKEQEAKRLQEEEQRKAKEQAAVAASAPVMNVTVDMQNSPACESYEMTPKSCKVPSVKVNEDNYGMDLNSDDSTDDESQPRKPIPAWASGNLLTQAIRQQYYKPIDVDRMYGTIDSPKLEELFNKSKPRYFKRTSSAVWHSPPLSSNRHHLAVGYGLKY
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.  Acts as a scaffold regulating CPC localization and activity.  The C-terminus associates with aurkb/aurora-B, the N-terminus associated with cdca8/borealin and/or cdca9/dasra-A tethers the CPC to the inner centromere, and the microtubule binding activity within the central SAH domain directs aurkb/aurora-B toward substrates near microtubules.  Activates aurkb.
What are the official names of this protein?
Inner centromere protein A, XL-INCENP, xINC, xIncenp, Mitotic phosphoprotein 130.
What is the protein family that this protein belongs to?
Belongs to the INCENP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome, centromere, kinetochore. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis (PubMed:10996078). Colocalizes to the equatorial cell cortex at anaphase (PubMed:10996078). Colocalizes with AURKB at mitotic chromosomes (PubMed:10996078).
Protein: BCHN_CHLAA
Sequence: MFLNPVVPNGYYNLRGGAMQSKATPIREDGIYHSFCGLVSVGWLYQKIKDSFFLILGTHTCAHLLQNTLGVMIFARPRFAVSLLEESDLSSSQPDISAQIEEIKREHHPSVIFLLSSCTPEVMKVEFEGLAASVSTPEVPVLFVPASGLDYTFSQSEDSVLQALIPFCPPAPPDDKRVVFLGSVNDAIADDFSLEAARLGIPVAGFLPASHFTELPPIGPGTVIAPLQPYLHKTATQLRNERGCTVLSSLFPFGPDGTRRFWEDLAAQFGMQVDLSEREAAAWERIKHHTDLLRGKKIFFASDTLMELPLARFLKACGAEVVECSTPYINRRFHAAELAALDGVRLVEQANFHRQLRTITETKPDLIISNIITTNPLVGQGTVAKWGTEYCFLPIHGWAGVNNLVTSFTRALQRHARLDPLGSDPIWLTGMMPGSSGGVISLQS
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: ALG14_CRYNB
Sequence: MSLGRYIGWSILAFTYLVLAILLRLIFLQPSKTSRASYRPKDAKCSLGVFLGSGGHTSEMKALLSTLDYERYQPRTYIYCHGDDLSLRAVSDIESSKGGLISSKMYYLLSLPRARRVGQPLLSTMVSVLKTLYIAALRLFLIPLLKNPRRPFVDLLIVNGPGTCVVLVLVSYIRRVRLEYTRIIYVESFARVKSLSLSGKMIRPLADRFLVQWPDASDSDNVIHKGLLV
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit ALG13 to the ER (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG14, Asparagine-linked glycosylation protein 14.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: 3MGH_PSEAE
Sequence: MSRDPILSLPWPDARPLPDTFFDRDALLVARELLGKVIRHRQGNLWLAARIIETEAYYLEEKGSHASLGYTEKRKALFLDGGHIYMYYARGGDSLNFSAGGPGNAVLIKSGHPWLDRISDHTALERMQSLNPDSQGRPREIGRLCAGQTLLCKAMGLKVPEWDAQRFDPQRLFVDDVGERPSQVIQAARLGIPKGRDEHLPYRFVDAAFAAFCTRNPLRRGQVAGRDYHLLGHQDPHLQ
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: YBAB_SALPB
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RR12_COFAR
Sequence: MPTIKQLIRNARQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IGAA_ECOLI
Sequence: MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETRSYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQRHRTRMMEIQAYYESCLNPQLITPSESLIE
What are the official names of this protein?
Putative membrane protein IgaA homolog.
What is the protein family that this protein belongs to?
Belongs to the IgaA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPMA_ECO45
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: IL6_VULVU
Sequence: MNSLSTSAFSLGLLLVMATAFPTPGPLAGDSKDDATSISLPLTSANKVEELIKYILGKISALRKEMCDKFNKCEDSKEALAENNLHLPILEGKDGCFQSGFNQETCLTRITTGLMEFQLHLNILQNNYEGDKENAQSVHMSTKILVQMLKSKVKNQDEVTTPDPTTDATLQAILQSQNEWLKHTTIHLILRSLEDFLQFSLRAVRIM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_ACTSZ
Sequence: MAIRPLHDRVIIKREEVETLSAGGIVLTGSAATKSTRAKVLAVGKGRVLENGTVQPLDVKVGDTVIFNDGYGVKAEKIDGEEVLIISENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_ELUMP
Sequence: MYSNLQKTDKAVFDAVEKELGRQRTKLELIASENFTSLSVMEAQGSILTNKYAEGYPGKRYYGGCEFVDMVETLAIERAKQIFGAEHANVQPHSGAQANMAAYLALINPGDTVLGLNLSHGGHLTHGHPMNFSGKYFKIVPMNVRKEDEQIDYEEAAKLALEHKPKVIMAGASNYSRIFDWKKLREIADSVDAYLICDVAHYAGLIAAGVYSNPVPYADIVTTTTHKTLRGPRGGLILCKEKHAKAVNSSVFPGQQGGPLMHVIAAKAVCFGEALKPEFKEYQTQVVKNAKELSTQLQKLGYRIVSGGTDCHVLCVDLTSKSMTGKAAEEALDKAGITTNKNTIPYDTQKPFITSGVRLGTPAVTTRGMKEAEMAAIASFIDNVLNNADNEAKLAEISKEVTAFLGKFLLYTELN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_BURM9
Sequence: MNKIRKGDEVIVITGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEDGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PLSX_NEIMB
Sequence: MITLAVDAMGGDQGLAVTVPGATAFLQAHPDVRLIMTGDETQLRQALTAAGAPMERIDICHTTQVVGMDEAPQSALKNKKDSSMRVAINQVKEGKAQAAVSAGNTGALMATARFVLKTIPGIERPAIAKFLPSDTDHVTLALDLGANVDCTSEQLAQFAVIGSELVHALHPQKGQPRVGLVNVGTEDIKGTDTVKQTYKLLQNSKLNFIGNIESNGILYGEADVVVADGFVGNVMLKTIEGAVKFMSGAIRREFQSNLFNKLAAVAALPALKGLKNKLDPRKFNGAILLGLRGIVIKSHGGTDETGFRYALEEAYHEAKSAGLSKIEQGVAEQLAALETAKAVQNENVGGL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: AROD_PYRAB
Sequence: MIATVILADSIKEAIEKIKSSSSDLYELRADSLKDYSKLELLEPYSEKLVVTIRSKDEGGFKELSDEKRLELYSKFLEIKPRYVDVEFRSKIKDEVMEIAKRVGSRVILSYHNFRETPPFGVLYNLLEDMESEGADIVKIVTHASSPKDNIRIIRLYEFADNLIAFCMGSKGKISRIFSSMYSPITYVALDKKAAPGQLTLEELRVILKILGEGR
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: SELA_PARDP
Sequence: MDPRSTLPSIDRLLRQAEARELIAHHGRDNVVGMLRRLLQDRRMAAGRGDRAAGERAAGEGVLDECAERLAAQARPSLRPVLNLTGTVNHTNLGRALLSRRAAEAAFRAMISATNLEYDLERGTRGDRDSHVEALICRLTGAEAATVVNNNAAAVMLMLNTLALGREVVVSRGELVEIGGAFRVPDVMARAGCRLHEVGTTNRTHLRDFANAVNEDTAAFMKVHASNYAIEGFTAEVPQADLAALARRHGIPLLIDLGSGSLLDLDAFGLPPEPTARQAIRDGADAVTFSGDKLLGGPQCGIIAGSRALVDRMRANPLKRALRVDKIILAALAETLQSHGDPERARAEIPTLRLLTRPQDEIRALAERLCPPVHAALSGLAEVRVVDCLSQIGSGAQPVDLLPSAGLGFAETGAVPVSRIAQAFRDLPLPVIGRVHKGEFLLDLRCLEDETPFLAQLDRLALAGPA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MROQ_STAA3
Sequence: MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
What is the function of this protein?
Participates in the regulation of the Agr quorum sensing activity and plays thereby an important role in virulence (PubMed:30833335, PubMed:30833334).  Mechanistically, elicits a protease dependent control of Agr activity without playing a role in the processing of the pheromone-precursor AgrD (PubMed:30833335).
What are the official names of this protein?
Membrane-embedded CAAX protease MroQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase U48 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNME_PROMS
Sequence: MDSIVTTEDTIAAIASAISIGKGGVAIIRVSGKDAINSCKKIVQTKSKYAWESHRVFRGFIQENKQNKFIDEVLILVMKSPNSFTGEDVVELHCHGGIIIVNKVLKILLSNNSRVRLANPGEFSQRAFLNGKIDLTQAESINQLINASNARSAELAFSGVQGEIKKKIDDIKNDLINQLCEIEARVDFEEDFTDFDYTKYLKNIKKVKEKIELLIENAKRNSYIHNGISIALIGKTNVGKSSLLNLLAKKEKAIVTNIPGTTRDVIEVNLTINDIPMKIIDTAGIRETHEQIESIGIKKSFGKIKESDFIIYIYSLEEGFNEEDKKIIQEIPKEKLITILGNKKDLIDCKNINSNELKHTILMSIKNNDGERLLIDTIIKKCGLKQVENINIFLNDRHLTNLSACLSNLNDTDEIIENKLPFDLLSIELRDGIQNLSKITGQELTEELLDNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFI2_CHRMO
Sequence: MATPSSATSLNVENIVFPSSVKPPGDTNTLFLGGAGVRGMEIQGNFVKFTGIGVYLEDKAIPLLAGKWKGKTAEELVNSVEFFRDIVTGPFKKFTQVTMILPLTGKQYSEKVSEMCVGVWKAHGTYTDADGATIDKFLEVFKDENFPPGASILFTTSPDGSLTISFSKDGMIPEAANIVLENEKLAQAVIESVIGKNGVSPATKQSLASRLSDLMNHFDEKATTDAEPNLSKNGL
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase 2, Chalcone isomerase 2, DgCHI2.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: PSBF_SOLBU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SSTT_GEOTN
Sequence: MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHILILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRTAPETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQNPYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLGTALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRRKEGKQVAIKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.