PharMolix/UniProtQA huggingface dataset:
Protein: EFG_PARD8
Sequence: MANNDKQLMFTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGETHDGTATMDWMAQEQERGITITSAATTTFWNYLGNRYKINLIDTPGHVDFTVEVERSLRVLDGAVATFCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGANYYEVVRQLKDVLGANPCPIQIPIGAEETFKGVVDLIKMKAIFWHDETMGAEYSVEEIPADLQAEAEEWRDKMLEALAECDDAIMEKYFDDPSTITEEEIMVAIRKGTLAMQINPMTCGSSFKNKGVQTLLDAVCAFLPSPEDTPAIEGTDPSDPDKIITRKPLFEEPLTALAFKIATDPYVGRLCFFRVYAGSINAGSYVLNTRSGKKERISRLFQMHSNKQNPMEVIGCGDIGAGVGFKDIRTGDTLCDENHPITLESMEFPEPVIGIAVEPKTQKDMDKLGMGLAKLAEEDPTFRVQTNEETGQTVISGMGELHLDIIIDRLRREFKVECNQGRPQVTYKEAITQPVELREVYKKQSGGRGKFADIIVRMEPADESFEGTLQFIDEVKGGNIPKEFIPSVQKGFEKAMKNGVLAGYPLDKLKVTLIDGSFHPVDSDQLSFEIAAIQAFKNASAKAGPVLMEPIMQMEVVTPEESMGDVIGDLNKRRGQVEGMETSRTGARIVKAKVPLAETFGYVTALRTITSGRATSSMQFSHYAQVSSSIAKQVLTEVQGRVDLIK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC25_ARATH
Sequence: MEQISNIAGGDTTKETMASLGLICEKDIHEQRLKIDSFIASPFRRSMNSLVERAQATAQSQVELMNLKADLREAEDELVKVLAVKTRKEARQMGIRDSISATQSRIEVLRRNLQLQKSKKDDSVRIISQQLQALSKSKDNAGKVTEDKADIHEAISWYNHALGFHVEAGHGVKFTFTNIDAKRPTREFSFTVHYGNDIYTLLDSDLQLDYINEMVQELNKTNDLFRFVRLMREQFLKSTLSELPTHSGQLQQETSAISASAPAISFSTDTNMSTPENKRSKVQVNRRQKRGSESPLLAPVSTSATRRSSRFKGKK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division.
What are the official names of this protein?
Kinetochore protein SPC25 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Chromosome, centromere.
Protein: TBA_DICPU
Sequence: LRGKEDAANNYARGHYTVGKELIEVCADRIRKLADQCEGLQGFLVFHSVGGGTGSGFGSLLLQRLALEYGGKKSKLDFCVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSFMLDNEAIYNICKKSLDIEKPTYTNLNRLIAQVISSLTSSLRFPGPLNLDINDIQTNLVPFPRLHFVLCSYAPVISKEKSEHENITVDAITNSVFSENNIMAKCQPHLGKYMACCLMYRGNIVPKEAQKAVQNIRNEKSKTVSFVDWSPTGFKCGINNSKPTTVLGENGDNMARTEKSVCMLSNTTAISQVFSRINHKFDLMYIKRAFVHWYVGEGMEEGEGL
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain, Alpha-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MIAB_TRIEI
Sequence: MNTNNRHYHITTFGCQMNKADSERMAGILDNMGLISSEDPNKADIILYNTCTIRDNAEQKVYSYLGRQAKRKHKQPDLTLIVAGCVAQQEGAALLRRVPELDLIMGPQHANRLQDLLEQVFNGNQVVATEPIHIVEDITKPRRDSKITAWVNIIYGCNEHCTYCVVPSVRGVEQSRTPEAIRAEMEELGRQGYQEITLLGQNIDAYGRDLPGVTKEGRNKYTFTDLLYYVHDVPGVERIRFATSHPRYFTERLIRACAELPKVCEHFHIPFQSGDNKLLKAMARGYTHEKYRRIIDKIRELMPDASISADAIVGFPGETEAQFENTLKLVEDIGFDQLNTAAYSPRPGTPAALWENQLGEEVKSDRLQRLNHLVGVKAADRSQRYMGRIEEVLVEDMNPKNAAQVMGRTRGNRLTFFEGDIAQLKGKLVKVKITEVRPFSLTGEVKEFVLV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_CROS8
Sequence: MSSVSQARSLGKYFLLIDNMLVVLGFFVVFPLISIRFVDSLGWAALMVGIALGLRQLVQQGLGIFGGAIADRLGARPMIVTGMLLRAAGFATMAVAHEPWVLWLSCVLSGLGGTLFDPPRSALVVKLVRPQERGRFFSLLMMQDSAGAVTGALIGSWLLQYDFRLVCGVGALLFVLCAGFNAWLLPDWKLSTVRTPLREGMGRVLRDRRFVTYVLTLTGYYMLAVQVMLMLPVMVNDIAGEPAAVKWMYAIEAVLSLTLLYPLARWSEKRFRLEQRLMAGLLVMTFSLVPIGLASNLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAFGGALGYAGGGWLFDAGRALHTPELPWAMLGVIGVGTFLMLWWQFSQKRLAPGLLEQES
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NLS1B_DANRE
Sequence: MAKGEGAEQYTNTSLLQKPSPDEVKLAKHETKSRLSVCSKLCYAIGGAPYQITGCAIGFFLQIYLLDVALLDPFYASIILFVGRAWDAVTDPTVGFLVSRTPWTRFGRMMPWIVLSTPFAVLCYFLIWYVPSVDQGKVVWYLIFYCCFQTLQTCFHVPYSALTMFISTEQKERDSATAYRMTVEVLGTLIGTAIQGQIVGMANAPCISTEIDLNSTGLEVAPDVNITDPHVSLQDLRNAYMIASGVICAIYVVCAVVLFLGVKEQKDTCRVRTEPMSFFQGICMVMGHGPYAKLVMGFLFTSLAFMLLEGNFALFCIYNLGFRNDFQNVLLVIMLSATLAIPFWQWFLTKFGKKTAVYIGTTSVVPFLISVVLVPSSLAVTYIASFAAGVSVAAAFLLPWSMLPDVVDDFKVQNPESQGHEAIFYSFYVFFTKFASGVSLGVSTLSLDFAGYVTRGCTQPGEVKLTLKILVSAAPIVLIIIGLLIFISYPINEEKRQGNRKLLNEQRENEMDSETDSTELNVV
What is the function of this protein?
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function.  Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain.  Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain.  Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons.  Does not transport docosahexaenoic acid in unesterified fatty acid.
What are the official names of this protein?
Sodium-dependent lysophosphatidylcholine symporter 1-B, NLS1-B, Sodium-dependent LPC symporter 1-B, Major facilitator superfamily domain-containing protein 2A-B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SFSA_CLOBK
Sequence: MKITKNILKAEFIKRPNRFQAYVKINEKIEMVHVPNTGRCKEILIPGSTVILREENNENRKTRYDLIAGYKGDMLISIDSQIPNKVVYEALMNFKIEILKEYTNIKREKTFGKSRFDFKLEKENGEVYYLEVKGVTLENDGLTMFPDAPTERGTKHILELIDVKNKGMGAGVLFLIQLNGVKKFTPNHKMDKNFGEALKLAKEKGVDILAYDCLVEESSISLNNPVSIEI
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RSSA1_SCHPO
Sequence: MAQVGRPNILNATDEDIKQLLAANCHIGSKNLEVRMDNYVWKRRSDGVHILNLGKTWEKLVLAARVIATIENPADVCVVSTRTYGHRAVLKFAAHTGATAIAGRFTPGNFTNYITRTYREPRLIVVTDPRADAQAIKEASFVNIPVIALCDTDSILNHVDIAIPTNNKGRKSIGLIWYLLAREVLRVRGTLSRSAPWDVMPDLYFYRDPEEVEREEEAKKAAAAAAEEAQVEEAVAAAEFEITDSAAGSVDPNVLAAATAGQVGENTWEGAGDWNTTGAAQTSDWTAAAEAQ
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RHGA_EMENI
Sequence: MYVSRLLLFLAPLLVKGQLSGSVGPLTSVSSKSQTKTCNVLDYGAVADKSTDIGPALSSAWDECADGGVVYIPPGDYAIETWVKLSGGKACAIQLDGIIYRTGTDGGNMIMIEHTSDFEFFSSTSKGAFQGYGYEFHAKGSSDGPRILRLYDVSDFSVHDVALVDSPLFHFSMDTCSNGEVYNMAIRGGNMGGLDGIDVWSTNVWIHDVEVTNKDECVTVKSPSKNILVENIYCNWSGGCAMGSLGTDTDISDIVYRNVYTWKSNQMYMVKSNGGSGTVSNLVLENFIGHGNAYSLDIDSAWSSMSTIEGDGVELKNVTIRNWKGTEADGSQRGPIKVKCASGAPCTDVTVEDFAMWTESGDEQTYVCENAFGDGFCLADGDGTSTFTTTLTASAAPSGYSAPSMDADLETAFGTDSEIPIPTIPTSFYPGATPYSALAGASVSSSQVPAASSSAEAKFVASPATSSPTATSTAISSVDPVSAATTTATSHGHGKSHHKHQCRAHRH
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins.  Active against linseed rhamnogalacturonan.
What are the official names of this protein?
Rhamnogalacturonase A, RGase A, RHG A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPH_PSEPF
Sequence: MSGFEQLFPGQLPRLVMFDLDGTLIDSVPDLAAAVDNMLLSLGRKPAGIESVREWVGNGAPVLVRRALAGGIDHSSVDDVEAEHALEVFMEAYGASHELTVVYPGVRDTLKWLHKQGVAMALITNKPERFVAPLLDQMKIGRYFKWIIGGDTLPQKKPDPAALFFVMKMSGIPASQSLFVGDSRSDVLAAKAAGVKCVGLSYGYNHGRPIAEESPTLVIDDLRKLIPGCLDTAAEITLPDAAQSPSGNAIVVVTRKLWMKVIKALARWRWRA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: TPS1_COFAR
Sequence: MAIINLPVPTNSSSEVNKHNHLRSCLPSGRATFTTLSAAAMRSATMAAANVREQSGQKQQLINRRSGNYEAPLWEFDYIQSLKNEYAGDIYVSRANELKEQVKMMLDEEDMKLLDCMELVDGLERLGLAYHFEGRINRLLSSDYKAIHEGNHQRNKEDLYAAALEFRIFRQNGFNVPQDIFNDFITEDGEFDESLSEDTMGLLSLYEASFLSLEGEATLDLAREFTTKHLNNYLGKENTDQNLRILVYHALELPLRWRAPRIEARWYIDAYERSPNVNPTLLELAKIDFNIVQAIHQQDLKHVSWWWKNIRIAEKLTFIRDRIVENFFWAIGAVFEPQYGSCRRMLTKVFALITMIDDIYDVYGTLEELELFTDAVDRWDVKAIDQLPDYMRVGYLGFFNSINEMAYDALKEQGVHIVEYLRKVWADLCKAYLQEAKWYYAGYTPTVEEYLENAWVSMSVPVMLMHAYAGVTNPMNKEAMDVLDTHDIVRCSSYLLRFADDLGTSPGEMKRGDVPKLVQCYMKEAGCSEEESREHVWFLLRETWKKMNKDSEWAESPFSKTFVTAAKNFGRVALVMYQYGDGHGLHSNPEAKDRILASLFSPVPPA
What is the function of this protein?
Monoterpene synthase (mono-TPS) involved in the biosynthesis of monoterpenes natural products, constituent of coffee beverage aroma (PubMed:23398891).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) into limonene, beta-pinene, sabinene and beta-myrcene, and, as minor products, alpha-pinene and alpha-terpinolene (PubMed:23398891).  Can also, with a low efficiency, use farnesyl pyrophosphate (FPP) as substrate to produce beta-farnesene (PubMed:23398891).  Not able to use geranylgeranyl pyrophosphate (GGPP) as substrate (PubMed:23398891).
What are the official names of this protein?
Limonene synthase, chloroplastic, Alpha-pinene synthase, chloroplastic, Beta-farnesene synthase, chloroplastic, Beta-myrcene synthase, chloroplastic, Beta-pinene synthase, chloroplastic, Sabinene synthase, chloroplastic, Terpinolene synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADRM1_CAEEL
Sequence: MAAMFSNTRSVASSSGHIVEFKAGRSRLEAGSGDTMRKVVAEPKKGLVFIKQSNDMLIHFCWKDRETGAVVDDLIIFPDDAEFKAVPGCPDGKVYMLKFKSGDMKLFWIQDSTPDVDKDLVKKVTDALNKPPTSRPAASRSAGSNANTDRQSAGGSLISSSDMNAPLGGIDQGQLMSLIQSLQGGNSDTLPISSVPRGEDASSEADCEPSTNAAEEGSSNPLSLNNPAIQQIFNNLGRSQKKEVAVSLATALSNETVAEVARNHAEELAPHLPTSDDPARELSETVRTPQFRQAADTLGHALQTGQLGPVVAQFGMDEATVGSANQGDIRGFAANLTKAEGGEDAAKTQNSDDDATREPEPKRNRPDNEDMDVD
What is the function of this protein?
May function as a proteasomal ubiquitin receptor.  May promote the deubiquitinating activity associated with the 26S proteasome.
What are the official names of this protein?
Proteasomal ubiquitin receptor ADRM1 homolog, Proteasome non-ATPase regulatory particle-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the ADRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLA2_TRYCR
Sequence: MKYLAAYALVGLSGGTPSKSAVEAVLKAAGVPVDPSRVDALFAEFAGKDFDTVCTEGKSKLVGGVTRPNAATASAPTAAAAASSGAAAPAAAAEEEEDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-A, P, L12E, P-JL5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: LOLD_BURPS
Sequence: MNDRVFEQTMNQNHQDGGARECVLEARGVTKTFVQGGFNVQVLDNAQVSVRRGEKLAIVGASGSGKSTLLHVLGGLDEPSAGQVSLLGKPFTQLAERERNELRNRALGFVYQFHHLLPEFTALDNVAMPLRIRRMSTEEARRHAREMLEQVGLGARAKHRPGELSGGERQRVAIARALVTKPACVLADEPTGNLDGSTADHVFHLMLELSRTLDTSFVIVTHDPDLAARCDRILRLRDGVLHEEPAVPV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CBPM_SALPA
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNTDWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: RS12_THEYD
Sequence: MPTISQLVKKGREKVEKKTKSPALQSCPQKRGVCVRVYTTTPKKPNSALRKVAKVRLTNGVEVIAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGTLDCAGVNNRRQSRSKYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MIOX_BOVIN
Sequence: MKVAADPDPSLVSQRDMEPEAAKDKDSFRNYTSGPLLDRVFATYKLMHTWQTVDFVRRKHAQFGGFSYKRMTVMEAVDMLDGLVDESDPDVDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALAGEPQWAVVGDTFPVGCRPQASVVFRDCTFQDNPDLQDPLYSTELGMYQPHCGLENVLMSWGHDEYMYRMMKFNKFALPPEAFYIIRFHSFYPWHKFGDYQQLCNEQDLAMLPWVQEFNKFDLYTKSSSLPDVAALRPYYQGLVDKYCPGILCW
What are the official names of this protein?
Inositol oxygenase, Myo-inositol oxygenase, MI oxygenase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT25_MOUSE
Sequence: MRKVDLCSVTEGTEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVKIEKLVIQSYLVRTLRIEKTTSKEPLDFEQWVEKDLVHTEGQLQNEEIVARDGYATFLRFIIVSAFDHFASVHSISAEGLTVSSLP
What is the function of this protein?
Component of the IFT complex B required for sonic hedgehog/SHH signaling.  May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium.  Not required for ciliary assembly (PubMed:22595669).  Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis.  Essential for male fertility, spermiogenesis and sperm flagella formation (PubMed:28430876).  Plays a role in the early development of the kidney (PubMed:29626631).  May be involved in the regulation of ureteric bud initiation (PubMed:29626631).
What are the official names of this protein?
Intraflagellar transport protein 25 homolog, Heat shock protein beta-11, Hspb11, Placental protein 25, PP25.
What is the protein family that this protein belongs to?
Belongs to the IFT25 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: ITPK1_MAIZE
Sequence: MASDAAAEPSSGVTHPPRYVIGYALAPKKQQSFIQPSLVAQAASRGMDLVPVDASQPLAEQGPFHLLIHKLYGDDWRAQLVAFAARHPAVPIVDPPHAIDRLHNRISMLQVVSELDHAADQDSTFGIPSQVVVYDAAALADFGLLAALRFPLIAKPLVADGTAKSHKMSLVYHREGLGKLRPPLVLQEFVNHGGVIFKVYVVGGHVTCVKRRSLPDVSPEDDASAQGSVSFSQVSNLPTERTAEEYYGEKSLEDAVVPPAAFINQIAGGLRRALGLQLFNFDMIRDVRAGDRYLVIDINYFPGYAKMPGYETVLTDFFWEMVHKDGVGNQQEEKGANHVVVK
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and participates in phytic acid biosynthesis in developing seeds (PubMed:12586875, PubMed:32123645).  Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5.  This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not (PubMed:12586875).  Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway (PubMed:12586875).  Also able to phosphorylate Ins(3,5,6)P3 but not Ins(1,4,5)P3, Ins(2,4,5)P3, Ins(1,3,4,6)P4 nor Ins(1,3,5,6)P4.  Has higher specific activity on Ins(3,4,5,6)P4 than Ins(1,3,4)P3 and Ins(3,5,6)P3 (PubMed:12586875).  Can also could use Ins(1,2,5,6)P4 as a substrate (PubMed:12586875).  Able to add a beta-phosphate to the 3 positions of Ins(1,2,3,4,5)P5 and to add beta-phosphate to InsP6 to yield 5-InsP7, thus exhibiting InsP6 kinase activity (PubMed:35635723).  Has also Ins(1,3,4,5,6)P5 phosphatase activity (PubMed:35635723).
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase 1, ZmITPK1, ZmIpk, Inositol 1,3,4-trisphosphate 5/6-kinase 1, Inositol-triphosphate 5/6-kinase 1, Ins(1,3,4)P(3) 5/6-kinase 1, Inositol-hexakisphosphate 5-kinase, Low phytic acid protein 2.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
Protein: USP4_LOTGI
Sequence: MKVSFSVTILFSVFNGAFSESLCSQMGGKCHSYYDVCWTRKYSYGHHLCTRYGEPPVCCFYDYFENDCIRRGGTCFDIRFSSCTNGRLVNDGCGGEYNYCCTPNHYRPYPYTQRSTYNGQYFNSQAKSYPYNRAHLYHRHTSFNRKPSYGNTPASRTTYTG
What are the official names of this protein?
Uncharacterized shell protein 4, LUSP-4.
What are the subcellular locations of this protein?
Secreted.
Protein: CO9A1_HUMAN
Sequence: MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLISQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP
What is the function of this protein?
Structural component of hyaline cartilage and vitreous of the eye.
What are the official names of this protein?
Collagen alpha-1(IX) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MNME_RHOPS
Sequence: MHPSDQTIFALATGQLPSAIAMVRVSGPRAGDLLTALTGSLPPPRTARRVLIRDQNQDLIDDGVALWFAGPASATGEDVAEFHIHGGRAVLAALVRALSAFDGVRPAEPGEFTRRAFENGKLDLTEAEGLDDLIHADTEAQRRQAVRQLGGLLGDRARRWRAQIIEATALIEAGIDFADEGDVQGELMAPALQTIAALHDEIAEVLAAQGRSERLRDGMVVAIAGPPNVGKSTLINRLARREVAIVSPHAGTTRDVIEVQLDLGGYPVTVIDTAGIRESNDPVEQEGVRRARARAAEADLVLWLGEGEMTGDAVAASAPVWRVRNKIDLRGGEGDGGPVGLPVEPLAAALRQTDGAWGGNAAFEISALRGQGLGELIAAIEDFAAQYFASGETALISRARHRTLLQDAAAMLQRSLQHDLPAELVAEELRLAGVALGRLLGRVDVEDVLGEIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPS1_LEPBY
Sequence: MLRWVREITGWMVWIPDKARYAGIRETSGCGLGGSPLWEI
What are the official names of this protein?
Uncharacterized 4.6 kDa protein, ORF1.
Protein: HSLV_DESAP
Sequence: MTFKGTTIVAVKRDGAVALAGDGQVGLGNGIIVKRDAVKLRRLYKDRVVAGFAGSVADAFALFERFEGKLEESQGNLRRAAVQLAKDWRTDKYLRRLEALLVVADREAVLLISGGGEVIEPDDGIIAVGSGGAFALAAARALARHTALPAVDIAREALQIASQICVHTNDRITVEQV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSME_SHIFL
Sequence: MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLG
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.