PharMolix/UniProtQA huggingface dataset:
Protein: PANE_NOSS1
Sequence: MNERKYAILGTGALGGYYGAKLQKAGSDVHFLLKSDYEKVNQDGLLVESKDGDFTLPQVNAYNDVAKMPKCDVVVVALKTTQNHLLPKLLPPIVKNDGIVLVLQNGLGVEEEIAEILPQVHIIGGLCFLCSNKVGAGYIHHLDYGQITLGEYAHGYSNMGITDRMQQISHDFQTAGISIELLEDLLLGRWKKLVWNIPYNGLSVVLNARTDELMADTYTRTLVEQLMYEVKAGAKSMGRNIPDSFIQTMLDYTVKMKPYRTSMKIDYDECRPLEVEAIVGNPLHKAQEVGVNLPQINCLYHQLKFLDGRNRTGQLTVDS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_BOVIN
Sequence: MWTLAGQGWWRGRALAAWVTEAARKGLLWPHLAPARGTAAESRAPDRCYSSADRKEKIDMSCFPVENTRNFSIIAHVDHGKSTLADRLLELTGAIDKTKNNKQVLDKLQVERERGITVKAQTASLFYNYEGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANFFLAFEAQLSIIPVINKIDLKNADPERVEKQIEKVFDIPGDECIKISAKLGTNVESVLDAVIKRIPFPKAHCRNPLRALVFDSTFDQYRGVIANVALFDGVVSKGDKIVSAHTQKTYEVNEVGVLNPNEQPTHKLYAGQVGYLIAGMKDVTEAQIGDTLYLHKQPVEPLPGFKSAKPMVFAGMYPVDQSEYNNLKSAIEKLTLNDSSVVVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLSSAKLIKEYREKEITIINPAQFPDKSKVTEYLEPVVLGTIITPDEYTGKIMMLCQARRAVQKNMMYIDQNRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTAELVKMDILLNGSIVEELVTVVHKDKAYSVGKAICERLKDSLPRQLFEIAIQAALGSKIIARETVKAYRKNVLAKCYGGDITRKMKLLKRQAEGKKKLRKVGNVEVPKDAFIKVLKTQSDK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LCMT1_RAT
Sequence: MATGSRESSFSSCASSCDFDDEGVRGTCEDASLCKRFAVSIGHWHDPYIEHLVRQSKERKAPEINRGYFARVHGVSQLIKAFLRKTECRCQILNLGAGMDTTFWKLKDEGLLPNKYFEVDFPMIVTRKLHTIKNKPLLFRPIMELHPEDTLQIDSHMLDSKRYAIIGADLRDLSELEEKLKKCNMNTQLPTLLITECVLVYMTPEQSANLLKWAARSFETAMFINYEQVNMDDRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLLNGWETASAVNMMELYSGLPRAEVNRIESLEFLDEMELLEQLMRHYCLCWATRGGQELGLKEITY
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: RS6_PROMT
Sequence: MSEQPYYETMYILRPDIPEEEVDSHLKKYSEILEKSETEVLDSQMRGKRRLAYPIAKHKEGIYVQLSHKGNGQQVATLERAMRLSEDVIRYITVKQDGPLPTPKPTSKENEPEKEEVKPTEEKTESPSKDEKKEDSKE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PVK2_GYNLU
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, GynLu-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSH_SALG2
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCSVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PSBZ_EUGVI
Sequence: NGWNDNKTFILIGSASWAALVLLVGSLNSFVI
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: GLMU_CHRSD
Sequence: MTLDVVILAAGQGTRMRSAKPKVLHALAGKPLVSHVLDTAEQLGATRTHVVIGHGAEQVETELDGRDVRFALQAEQKGTGHAVAQTLDELGDGKVLILYGDVPLIRAETLTALLDEVDERRLGLLTVTLDDPGGYGRIVRDAEGRVTRIVEHKDASEAERGITECNTGIVAATGTQLKRWLPQLSAENAQGEYYLTDIFAMAAAEGIEVATASPASALEVEGVNNRSQMAALERAYQRDRAERLLTEGVALADPARFDVRGRLQCGHDVFIDVGCVFEGDVTLGDGVSVGPYTLIRDSHVAAGTVIEAHSIIEGAEVAEQAHIGPFARLRPGTRLARQSKVGNFVETKNAEVGEGSKINHLSYVGDASLGGGVNIGAGTITCNYDGANKHRTEIGDDVFVGSNTALVAPVALGAGATIGAGSTISRDVEAGALAVARTRQTTRAGWKRPRKSS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_CERS4
Sequence: MTQHDRLLIIDFGSQVTQLIARRLRELNVYCEIHPYQNVTEAFLKGFAPKAVIFSGGPSSVFAEGAPMPPAGVFDLGVPILGICYGQQVMMHCLGGKVERGHGTAEFGRAFVTPTAERLAILDGWFEEGREQVWMSHGDHVSQIAPGFQVFGTSPNAPFAITGDPARHFYAVQFHPEVHHTPKGAKLYENFVRLAGFKGDWTMGAYREEAIARIRAQVGDQKVICGLSGGVDSSVAAVLIHEAIGDQLTCVFVDHGLLRLGEAEQVVKMFRDHYNMPLIHADESDLFLGALEGVSDPEVKRKTIGRLFIDVFQKHAADVGGATFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPEKMGLKLVEPLRELFKDEVRALGRELGLPESFIGRHPFPGPGLAIRCPGEITREKLEILRRADAVYIDQIRRHGLYDEIWQAFVALLPVRTVGVMGDGRTYDYACALRAVTSVDGMTADYYPFTHDFLGETATRIINEVQGINRVTYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: LPXK_SHEDO
Sequence: MQRWINNIWYGSNPIKWLLVPLSGLFWLISSLRRKKFAGSPSASEALGVPVIIVGNITVGGSGKTPMVIYLIELLRRQGYRPGVISRGYGVKIDGVKLVEAQASAVDVGDEPAMIVARTQVPMAVGPDRLAAVSLLQRHYDIDVIISDDGLQHYKLTRDIELVIIDGARRFGNGYLLPAGPLREGLWRLKTIDWLINNGGKAQDNEVLMQLEPKPLLKVKSSQPGLESLDKALPVVAMAGIGNPARFFDSLSGQGYQLKHTLAFDDHQAFDAQALIALAGDLPLIMTEKDAIKCRDFAQDNWWYLPVNARLNADFDKALLARLAPLVQIKP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: TNAP2_HUMAN
Sequence: MSEASSEDLVPPLEAGAAPYREEEEAAKKKKEKKKKSKGLANVFCVFTKGKKKKGQPSSAEPEDAAGSRQGLDGPPPTVEELKAALERGQLEAARPLLALERELAAAAAAGGVSEEELVRRQSKVEALYELLRDQVLGVLRRPLEAPPERLRQALAVVAEQEREDRQAAAAGPGTSGLAATRPRRWLQLWRRGVAEAAEERMGQRPAAGAEVPESVFLHLGRTMKEDLEAVVERLKPLFPAEFGVVAAYAESYHQHFAAHLAAVAQFELCERDTYMLLLWVQNLYPNDIINSPKLVGELQGMGLGSLLPPRQIRLLEATFLSSEAANVRELMDRALELEARRWAEDVPPQRLDGHCHSELAIDIIQITSQAQAKAESITLDLGSQIKRVLLVELPAFLRSYQRAFNEFLERGKQLTNYRANVIANINNCLSFRMSMEQNWQVPQDTLSLLLGPLGELKSHGFDTLLQNLHEDLKPLFKRFTHTRWAAPVETLENIIATVDTRLPEFSELQGCFREELMEALHLHLVKEYIIQLSKGRLVLKTAEQQQQLAGYILANADTIQHFCTQHGSPATWLQPALPTLAEIIRLQDPSAIKIEVATYATCYPDFSKGHLSAILAIKGNLSNSEVKRIRSILDVSMGAQEPSRPLFSLIKVG
What is the function of this protein?
May play a role as a mediator of inflammation and angiogenesis.
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 2, TNF alpha-induced protein 2, Primary response gene B94 protein.
What is the protein family that this protein belongs to?
Belongs to the SEC6 family.
Protein: PEX10_PICAN
Sequence: MFKLLSFANAPAIVRANQKDSYFESRLHNQLLDVVKAIKGSHFVHKYPEELRTLATALYLCLTTLVGSKTLGEEYVDLVYVSRDGRKIPKFASRFGFVVAYVLFPYAVRQLLQKLKAQQSRLAQLVSGVSYMNVMDLLNLHLALFYFTGKYYQFAKRLFGLRYAFGYRVDKNQQRARGNYELLGLLIIFQTVFKNVANLRKLWGATKTVQDSGDLIYRFRDQTSDVIDLADPKVLPYLPEASRTCMLCLSPMKDPSCGECGHVFCWKCVLDWVKERQECPLCRAKMRESQLLPLR
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane.  PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase.  When PEX5 recycling is compromised, PEX10 catalyzes polyubiquitination of PEX5 during its passage through the retrotranslocation channel, leading to its degradation.
What are the official names of this protein?
Peroxisome biogenesis factor 10, Peroxin-10, Peroxisomal biogenesis factor 10, Peroxisome assembly protein 10, Peroxisome assembly protein PER8.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein.
Protein: CH603_NITHX
Sequence: MSAKDVRFSGDARDRMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELDDRFENMGAQMVREVASKTNDTAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDIAAAAVVKDIGKRAKPVASSAEVAQVGTISSNGDTAIGKMIAQAMQKVGNEGVITVEENKSLETDVDIVEGMRFDRGYLSPYFVTNAEKMTAELDGAYILLHEKKLSGLQAILPLLEAVVKSGKPLLIVAEDIEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGQLISDDLGIKLENVTVDMLGRAKKVVIDKENTTIVNGAGKKKDIEARVGQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEIEVKEKKDRVEDALNATRAAVQEGIVPGGGTALLRAKKAVGRIANDNPDVQAGINIVLKALEAPIRQIAENAGVEGSIVVGKVLENKTETFGFDAQKEEYVDMVAKGIIDPAKVVRTALQDAASVAGLLVTTEAMVAELPKEEPAPAMPGGGGMGGMGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT19_DICDI
Sequence: MVRSRWKGIYVAKELQNYNTVTNPTIVTTERSSVIVPYYLTKTIYVYNGRKYVGVKITEKSLGRKLGEYVLTKKVEKYKASGKSKKK
What are the official names of this protein?
Ribosomal protein S19, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NU3M_TETNG
Sequence: MNLLLTILFITTILSLILAIVSFWLPLMTPDYQKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWGDQLPSPMFTLLWASALLIMLTLGLIYEWLQGGLEWAEK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NUSB_PSEE4
Sequence: MISDESDRFNPRDPKPADAGKPSKSAKRREARKLATQALYQWHMAKHSLNEVEAQFRVDNDFSDVDGAYFREILHGVPAKKVEIDEALKPCLDTPLEELDPVELSVLRLSAWEFMMRADVPYRVVINEGVELAKVFGATDGHKFVNGVLDKLAPRLREAEVRANKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ORF6_BPCHP
Sequence: MESLVKLHIGLIDMLASCCLLCFSICLESIQLEERFLLLILVMLLLRVLKVLILSFRICLVRLFSVIILDIMFRKDGEGNEV
What are the official names of this protein?
Uncharacterized protein ORF6.
Protein: Y1894_STRT1
Sequence: MMLLDLEEKTRVLIEDIVERSAIGSGSIFVLGLSSSEVIGGIIGKASSREIGQRIVKTILEVLEPKGIYLAVQGCEHLNRALVVERELALAKDLEIVNVLPTLHAGGSGQLAAFDYMEDPVEVEEILAQAGIDIGDTSIGMHVKRVQVPLRPIISELGGAHVTALASRPKLIGGARAEYLADPIRKN
What are the official names of this protein?
UPF0340 protein str1894.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: PAT_SHISS
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMQLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQADQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: TRPF_METM5
Sequence: MFIKICGIKTPEELEIVENYGNATGVILECVSKRRIGFETAKNLVNLANIPVFAVSTTSDVSVWENIIELTGTNYLQMHSDIDQKAIDFIKNEYGCFIMKSFKIPEKSESPENDAQKIISDIESYEVDRILLDTGKGCGQTHDHRISQILAKKFDIVLAGGLDPDNVLKIVKTVKPFGVDVSSGVENNNSKDEELIKRFCENVKSVKL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL6_FRAP2
Sequence: MSRIGKKPVAIPSGVTINVAAGNQVEVKSTKATLNKTFSSDVTFNIEDGVVTVTPKNNSKNAIAQSGTARAILNNMVEGVSKGFERKLKIIGVGYRAKAQGSELNLTLGFSHPVVYKLPQGITAETPAPTEIILKGADKEVLGKVASEIREYRKPEPYKGKGVRYEDEYVAKKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PDXK_ECO57
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMLVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: VHS2_YEAST
Sequence: MDTSNHNQDHDSHVAAQRENDNNYMPPSPSMSESSMIFERNVEDPSYLYKTVSNNAANSLSRQSSRTSLFNHNNSSNRNFHNLSQRSSAVNLHLQPSRTNESIASYQTYNPDFVVQTPLDHRRTLENFVPPALDAGCSIVTDDTTGLDDVDMVYSRRPSTIGLDRALGRTRSLSSQSFDNETSPAHPRSPNDHGSRLLRFYSYADMLSDDNNNNVSNATSTSSTANPLRRPPMQGHYSFSSSLLNSPSHLPSPPSASASPPQHMNFTNPFIISRRYSNTTINNANGGTSAGSTTGAALSRSPSNQQYLLKQQRSPSGSARSRRNSNRPGSAANIMIGKPKSKFHMESSGSEGFSSEEEDNTMIERDKLNLKQKLQSQLAQPPSIANMVNDNHNNTNKHKNTINNNIKNSPAFTNSNPSSKSNSNSTITSMNPDTTK
What is the function of this protein?
Can suppress the synthetic lethality of the hal3 sit4 double mutation when overexpressed, suggesting that it is involved in the G1-S transition.
What are the official names of this protein?
Protein VHS2, Viable in a HAL3 SIT4 background protein 2.
What is the protein family that this protein belongs to?
To yeast MFL3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S52A2_PAPHA
Sequence: MAAPTLGHLVLTHLLVALLGMGSWAAVNGIWVELPVVVKHLPEGWSLPSYLSVVVALGNLGLLVVTLWRRLAPGKGERVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLALACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECSPAPTNGTSGPPLNFPERFPASTFYWALTALLVTSAAAFQGLLLLLPSLPSVTTGGAGPELPLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLLAITSALTNGVLPAVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLGMLFGAYLMVLAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQMGSLLGAGTMFPPTSIYHVFQSRKDCVDPCGP
What is the function of this protein?
(Microbial infection) In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
What are the official names of this protein?
Solute carrier family 52, riboflavin transporter, member 2, Porcine endogenous retrovirus A receptor 2, PERV-A receptor 2, Protein GPR172B, Riboflavin transporter 1, RFT1.
What is the protein family that this protein belongs to?
Belongs to the riboflavin transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSRP_EXIS2
Sequence: MPKGTSSKVLANNKRASFDYAIEDTIEAGLVLTGTEIKSVRKGKISIGDAFVRFDGGEAILWNSNIAHFEQGNRYNHEQLRPRKLLLHKKQIATLMGSVSRDGYTIVPLKIYIKNGYAKCLIGLGRGKKKFDKRDDLKKKDAKRDIDRALRDKQKY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MMAB_BOVIN
Sequence: MAVWGPGGRLGLRGCLGARKLLCPRFQSRGPQGVEDGDRPQPSSKTPKVPKIYTKTGDKGFSSTFTGERRSKDDQVFEAVGTTDELSSAIGFAMELIAEKGHPFVEELQKIQCSLQDVGSALATPRSSAREAHLKHATFEAGPILELEQWIDKYSRQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQTGETDANVVKFLNRLSDYLFTLARYTAMKEGNPEKIYKKNDLSDRT
What is the function of this protein?
Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191).  Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA (By similarity).
What are the official names of this protein?
Corrinoid adenosyltransferase MMAB, ATP:co(I)rrinoid adenosyltransferase MMAB, Methylmalonic aciduria type B homolog.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YUY1_CAEEL
Sequence: MAPKKSKKSKKEESMIDFVEEEVTGDVDEDGFEQAEDMPDEVDSDEDEPPKKKKKVVKKEIKQELELTDEKLQELLEKYEASKATATKTKDDFKHLPKSQRGKALKRALRKDKRARQGERAQIRDELGESAPQKEVPKTIESMREYDATMVNEEDDEVEHDEANDEFAPYFNRETSPKVMITMTPKAKITTFKFCFELQKCIPNSEIFTRKNVLLKTIIEQAKEREFTDLLVVHEDRKKPNGIIFCHLPEGPTAYFKINSLTFTQDLKKFGESTSHFPEVILNNFNTRLGHNIARMLACLFPHDPKFTGRRVVTFHNQRDYIFFRHHRYEFKKEGSKAALLELGPRFTLRLKWLQKGTFDAKWGEFEWVLKRHEMETSRRRFFL
What are the official names of this protein?
Brix domain-containing protein F44G4.1.
Protein: LPE10_CANAL
Sequence: MIPIRSSITRILPNGFLSKPFLRQLNKKSKPNPHKNKNFDSFNEVFIHKTLLSSIKQHNDTDYVRCSIFNANGDMIQHGKEILKSQFIKRYNLTPRDFRKFNWQRSATGTTTTSSSSSSSAGQTSSGTSKSSSSSSSSSSPHSTISALSLSNSSLGSSTNVDIVPNITIRRNSILVQLLNIRALINHDQLIIFDNSSSFQNSHVSSYTHSQCLKDLSQRLKSTNLDGLPFEFKALEGILIYIVSNLNMEMKVHNTVLQNIITGLEDSIDRNKLRYLLIESKKIHQFHRKITLIKNCLEDLLENDDELNDLYITEKFNSEGDGQPRQGTNHEEIEMLLENYYQTIDEIVQIVENLKNQIKTTEDLINVVLDSNRNQLMLLGLKFSTGLLSMGVALYVSALYGMNLENFIEEIDGGFEVVTVVSTIALIALLLFSVKQLKKVEKVTMTSLNDQRK
What is the function of this protein?
Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis.  Modulates the conductance of the MRS2 channel.  Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter LPE10.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIBL_METP4
Sequence: MKRIVATGTFDILHPGHIYYLEESRKLGDELHVIIARDENVRHKPKPVIPEQQRLRMVQSLKPVDYARLGSTTDIFEPIREIQPDIITLGFNQFFNEEKLKCDLEENGISAEVVRIEGYSGEGFCSSRNIMKQILIRRCKELQDDSTD
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: RS6_CLOBK
Sequence: MRKYETVFILNPALDEEGYKANVEKFKGVIENAGGTVDNVDLWGKRKLAYEVKKVSEGYYTLMNFTADTELPKELDRVFRITDTVIRHMIITQE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.