PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_CALFG
Sequence: MIDRYKHQQLRIGSVSPQQIRAWANKTLPNGEIIGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKEFEGLVYCDFSFARPIAKKPTFLRLRGSFESEIQSRKYSIPLFFTTQGFDTFRNREISTGASAIREQLADPDLRIITDHSLVEWKELGEEGSTGNEWEDRKIGRRKDFLVRRIELAKHFIRTNVEPERMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDPLTTSTSTPGESVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHVASNIGIAKSKIREKEPIVWEILQEVMQGHPVLLNRAPTLHRLGIQAFQPILVEGRAICLHPLVRKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPTIGDPISVPTQDMLIGLYVLTIGNRRGICANRYNPWNRGNSQNERVNDTNYMYTKKEPYFCSSSDALGAYRQKRINLDSPLWLRWRLDQRVIASREVPIEVQYESLGTYHEIYGHYLIVRSIKKEILCIYIRTTVGHISFYREIEEAIQGFCRAYS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPB_WOLSU
Sequence: MEGRITQVMGPVVDVDFDSYLPAINEALDVNYDIEGHPKKLVLEVAAHIGDSRVRTIAMDMTEGLTRGTKVVARGKSIEVPVGEQVLGRIFNVVGDVIDGGDELKEPVKWSIHRTAPTFENQSTKTEMFETGIKVVDLLAPYSKGGKVGLFGGAGVGKTVVIMELIHNVAFKHSGYSVFAGVGERTREGNDLYHEMKESGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLASEMGKLQERITSTKKGSITSVQAVYVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILDPQVVGEDHYKTATGVQQVLQKYKDLQDIIAILGMDELSEEDKRVVERARRIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFKGILEGKYDQIPENAFYMVGGIDEVLEKAERLKANA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBIB_AZOCH
Sequence: EFEAAIRTVCEPIFEKPLKDISFGQLLLRLFQTARRFNMEVQPQLVLLQKTLLNIEGLGRQLYPELDLWTTAKPFLERWMRKRMSPKAMLDNLQGQLEQLPHLAQMTRAALEGMARPAHGAPPPRDRHILRLLGAALLAGGVLLASRAPLNVADAWPGWLMLASGLYLLVRRQRFPD
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEC1_SPHAL
Sequence: MSGKTVIVLLSGGLDSMVCAGLAREAGARIVALTIDYNQRHRVELESAARIAAHVGAAEHIVLPLDLRRFGGSALTADIDVPKDGVGTDIPVTYVPARNLIFLSLTLGLAEARQAADIVIGVNALDYSGYPDCRPAFIQGFEKLAALATRDGDQGVRFHIHAPLQHMTKADIAAEAARLGMDAAMSWSCYDPTPEGLHCGACDSCRLRRKGFADAGLADPTRYA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase 1, 7-cyano-7-carbaguanine synthase 1, PreQ(0) synthase 1, Queuosine biosynthesis protein QueC 1.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MSC6_YEAST
Sequence: MLSHNALRAFDCSKVIISRRCLTSSTSIYQQSSVHLQETDDGHSGNREKHVSPFERVQNLAADLKNELKAPDSDINEVFNDFKDKIESLKQKLRNPSPMERSHLLANFSSDLLQELSYRSKNMTLDPYQVLNTLCQYKLARSQHFTIVLKYLLYNQSPQDVIALWVKYLETISENPVILLQNSSSRAHMQNIAITTIAYLSLPENTVDINILYKILQIDRKMGQVLPFNMIRRMLSTEFSSLERRDVIIKNLNTLYYQYTVQDSDHFLSQIENAPRWIDLRDLYGQYNKLEGEKNVEIISKFMDKFIDLDKPDQVVTIYNQYSKVFPNSTSLKDCLLRAVSHLRAKSSKEKLDRILAVWNSVIKPGDNIKNTSYATLVNALTDSGNFNHLKEFWEEELPKKFKKDPIVKEAFLLALCQTSPLKYDQVKGELAETVKTKKLFNKVLLLMLDDEKVSEEQFNTFYYNHYPSDGVLPPTLDTLSIKMYANYKFQAEDTRPQFDLLQSVSINPTDYEKVEKITKAFISVCPTVEPIRQLYKQLGTHLNARNYADFISAEFNKPDGTVAEAKNLFSDFLSYQKTRKRNVDNTPLNALLLGFCDKLYKSKHSEYVPYIEKYYNLAKDSSIRVSNLAVSKILFNLATFARNTQQLSDKEVAFINQFMRDLGTNEGFRPNPKDIQILKECDGITVPEKLT
What is the function of this protein?
May be involved in the control of meiotic sister-chromatid recombination.
What are the official names of this protein?
Meiotic sister-chromatid recombination protein 6, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOD_RUTMC
Sequence: MKGLFISGSGTNVGKTFVAQYLIRLLSNTLKVSARKPVESDCENKNGRLIPKDALLLSKACNINEPIDKVCRYKLESCSSAQMASQDSGLKLTLDDLVDACMSDEFVIVEGTGGLLSPIARQALNSDLIQALDMPVVLVIKDELGAVNQALLSINSAQSCGLSISMLVLNQIQPNFLKNAQAIKQHTDIDINVFNQNHLASFERKVKKILLVI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MICUM
Sequence: MTIIRKKHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDSDKIPFHPYYTVKDFLGVLFLFMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALILSILILALMPLLHTSKQRTLTFRPITQTIYWILVADLLTLTWIGGQPVEHPFIIIGQTASIAYFTIIMILMPIAGMIENNILNLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: REX_STRR6
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDTDVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_PARPJ
Sequence: MTDSNKKIYVSDVTLRDGMHAIRHQYSLQSAVAIAQALDEAGVDSIEVAHGDGLAGSSFNYGFGAHTDLEWIEAVAATVKRAQVATLLLPGIGTVHDLRAAYDAGARVVRIATHCTEADISKQHIEYARSLGMDTVGFLMMSHMTSPEALAKQAKLMESYGAQCVYVVDSGVALNMRDVAERFDAFKAVLDPATQTGMHAHHNLSLGVANSIVALEHGCDRVDASLTGMGAGAGNAPLEVFIAAVDRMKLKHGCDVKQLIDAAEDIVRPLQERPVRVDRETLALGYAGVYSSFLRHTEAAAAKYGLSAFDIMVELGKRRMVGGQEDMIVDVALDMLKARELANQEAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: DAPA_SYNY3
Sequence: MADFVSTSPFGPVLTAMVTPFNADGGVDYGVAEKLADHLITHGSDGLVVCGTTGESPTLSWEEEHELFRVVKQTVGDRGSVIAGTGSNCTREAMEATQIAAKLGVDGSLQVVPYYNKPPQEGLLAHFQAIANCAPELPLMLYNIPGRTGQSLAPETVYRLAEVENIVAIKEATGSLEQASLIRAHTPDDFAIYAGDDVLTLPLLAVGGAGVVSVASHLVGDRLQAMVQHFAQGATAQALEIHLQLIPLFKILFCATNPIPVKTALGLQGWPVGSFRPPLCALSPGHTEQLRDVLRDLALLP
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_SULDN
Sequence: MDYLQIKKSPKLHGEIKISGAKNAALPLIAMSILAKNIVTIKNLPHVADIKTLLKLLSNLGAECSSSWENYSTTINTSTLNQTKATYDIVKTMRASILVLGPILARFGHCEVSLPGGCAIGQRPIDLHLKALEQMGAVINIEAGYIHAIAPDGLKGCNIIFDKITVTGTANIVMAAALAKGVTTITNAAREPEVVQLCEILNASGVKIEGIETAVLTIHGTGGELLEIAPFSVIPDRIEAGTYLCAGAITKSELTLKGANAKHLGAVLSKLEEMGSKFTITDDSITIHPSKIIKHVKIVTQEYPAFPTDMQAQFLALATQADGTSIIEERLFENRFMHVSELQRMGADISLNGNVATVNGHSKLSGTDVMATDLRASSALVLAGLVADGITDVHRIYHLDRGYDSLEKKLQNVGADISRLKE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_FRASN
Sequence: MPSGSVLMAADDGFHGPTPDVFKPKSWFEFDLGPIDFYFNKWSALTLFVALFVGGFLWLGFRKATLVPRGLQNFCESIYDFVDLQIAQNVIGERGRTFSPYLTILFCFILVSNVMAVIPVAQFPTTSRIALPMILAAVSWFIFNIVGIREHGAGTYFKDMLVPAPTAPLFVKVILAPIEFVSTMIARPATLAIRLFANMFAGHMLLLVFALGADYLLPKPQFVFGLVSGLMAIALTLFELMIDVLQAYIFTVLTAAYIGGAISSHGGGDHAADHSPIHGHETSAPVTAAGAVARA
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTAD2_SYNAS
Sequence: MAKTELDLLIRGSVLLTMREEEAVIENPVVGIRNGKIVLIMQNDLFTEEEYTARKVLDRSNTLIMPGLVNTHTHLAMSCFRGLADDLPLMAWLHEYIFPAEARHVNPEMVYAGSLLAMAEMILSGTTTFCDGYFFVDQVARAAKDAGMRAVVCQGFIDFPTPDTSDPSRQMETAERFIGTWKDASPLIQPALFCHSPYTCSPETLVRIKEAARREKILYVLHLSETREEVSLIQDCYGKRPALHLHNLDVLDPDTLAVHCVWLDEEEQGVLADCGVRVSHTPQSNMKLAAGIAPVPAMQAMGISVSLGTDGSASNNDLDLFREMDSTAKIHKVATGNPAVMDAARVVRMATSEGAGALGLQDRIGSLEVGKAADLIILDLNQPHLTPMYHPFSHLVYAASGADVLTTVIDGNVVMENRKILSFDLEAIMREVEKIAEKIRKSCRK
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase 2, MTA/SAH deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: RL13_THEMA
Sequence: MARYFPVQKTTMIKPEEVERKWYVVDASGKVLGRLATRIAKILMGKHKPNYTPHVDTGDYVIVVNADKVVLTGKKLDQKVYYWHSGYPGGLKSLTARQMLEKHPERLIWLAVKRMLPKNRKGRKMLKRLKVYASPEHPHQAQKPEPIEL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL10_ACIC5
Sequence: MALTKARKAERIETLAKELEHSTSAIIGTFAKLTVSQDFELRQKVRAAGGRYRVVKNKLAARASKGTQIEAALQGLKGVSSVAYTSGDPVALAKAMADWVKENAEFTFKLGIVDGKVITVEEVDQLAKMPGKEEIFSKLLYLINAPAQRLATVMAATGRDLAVVINQGVEKGKFSGEQASA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AMPG2_RICTY
Sequence: MNFKCVQFQSIFNILFILIISFPGGLIYLLTGSTLSFWLRESEFDKITIGLFGLVNFIYILKFLWGPLLEKISFSTLSNRGYKYCLVITLINCIVCVYVLTSFNPNTNFTPFVLCLIVLAFFSSIYDMLIQSSQMLLITDKNWGISEAACTTGFRIGILISGSGALYLSTIISWQDVYRTMAILCIPSLLLIIFYPLKFKDKMIANDFDKFFSAFYDFIKKPKWIVIISFMLLYRLQDSFLSIMPNMFYLDIGYTKQDLAIGYKAFGMCAAIFGGVIGGFLCRKYEYSYLLKRVLIYHALSSLSFIYLYFLNQDIISLYIAVFCQEFTKGLTMSPFFSYQLKCCSSRYCITQIALITSITNVGTILIGSISGYAATYLGWSYFFIVAGLCFIPAYILILYLPKTINSV
What are the official names of this protein?
Putative transporter AmpG 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14E_STAMF
Sequence: MPAIEIGRICVKVAGREAGRKCVIVDIIDENFVLITGPKSLTGVKRRRANVKHIEPLDKVIDISRGASDEEVLRAIANAGLTEFMKEIVKPKLVPV
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: PA2B_NAJPA
Sequence: NLYQFKNMIHCTVPSRPWWHFADYGCYCGRGGKGTPIDDLDRCCQVHDNCYEKAGKMGCWPYFTLYKYKCSKGTLTCNGRNGKCAAAVCNCDLVAANCFAGAPYINANYNIDFKKRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows anticoagulant activity, has cytotoxic activity and affects neuromuscular transmission in vitro.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 nigexine, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_BURCH
Sequence: MNQVTESAVQFDVVTLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLARPLEAAIDAAKAAQAEQGIASTRVVMMSPQGAPLTHDRAVRMAQEPGVVVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDSLSAVQDSFADGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEKWRRQEALRNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKDAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRG3_HUMAN
Sequence: MSEGAAAASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVWNRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTITRAPTRFPGHRVPIRASPRSTTARNTAAPATVPSTTAPFFSSSTLGSRPPVPGTPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAASSSSSSSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLNDGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDPTDHLGIEFMESEEVYQRQVLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEQLKVPQNGKSYSLKASSTMAKSENLVKSHVQLQNYSKVERHPVTALEKMMESSFVGPQSFPEVPSPDRGSQSVKHHRSLSSCCSPGQRSGMLHRNAFRRTPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLPIQLWCVERPLDLKYSSSGLKTQRNTSINMQLPSRETNPYFNSLEQKDLVGYSSTRASSVPIIPSVGLEETCLQMPGISEVKSIKWCKNSYSADVVNVSIPVSDCLIAEQQEVKILLETVQEQIRILTDARRSEDYELASVETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQRDSALTK
What is the function of this protein?
Direct ligand for the ERBB4 tyrosine kinase receptor.  Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor.  Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors.  May be a survival factor for oligodendrocytes.
What are the official names of this protein?
Pro-neuregulin-3, membrane-bound isoform, Pro-NRG3.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-3, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-3]: Secreted. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Note=Isoform 3 is also proteolytically released as a soluble form.
Protein: CRVP5_VARAC
Sequence: MILLKLYLTLAAILCQSRGTTSLDLDDLMTTNPEIQNEIINKHNDLRRTVDPPAKNMLKMSWDNIIAESAKRAALRCNQNEHTPVSGRTIGGVVCGENYFMSSNPRTWSFGIQSWFDERNYFKFGFGPTRAGVMVGHYTQVVWYKSYKMGCAINLCPNEPLKYFLVCQYCPGGNVVGRKYEPYAIGEPCAACPNNCDNGLCTNPCEHSNQYINCPDLTKQ
What is the function of this protein?
Blocks ryanodine receptors, and potassium channels.
What are the official names of this protein?
Cysteine-rich venom protein VAR5, CRVP, Cysteine-rich secretory protein VAR5, CRISP-VAR5.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_PARL1
Sequence: MTATIIDGKIIATELRARVAVEVARLKKDHSLTPGLAVVLVGNDPASEVYVRNKGIATTEAGMNSFEFKLPAETSEADVLAKVRELNADPAVHGFLVQFPVPNHISQQAVIDAIDPVKDADGLHPLNAGRLASGLPAMVPATPEGCVIMAKRAGGDLSGKHAVIIGRSNLVGKPVAQLLLKENCTVTIAHSRSRDLPSIARQADILVAAVGRPGMVRGDWVKPGAVVIDVGINRVPAPEKGEGKTRLVGDVLFDEAAEVAGAITPVPGGVGLMTVACLLRNTVIAACRQNGIALPQDF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ASNA_EDWI9
Sequence: MKKSYIEKQQQISFVKAHFSRQLEQRLGLIEVQAPILSRLGDGTQDNLSGHEKAVQVKVKNLPQDAFEVVHSLAKWKRKTLGMYDFAPGEGLYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERTPAYLQETVRHIYAAMKTTEAEVCAQYGLTPFLPAEIHFIHSEALLRRYPDLDAKGRERAITHELGAVFLIGIGGRLSNGQAHDVRAPDYDDWTSLGAEGFGGLNGDILVWNPVLGDAFELSSMGIRVDAKALKRQLALTDDEDRLALEWHQSLLRGDMPQTIGGGIGQSRLVMLLLQQQHIGQVQCGVWPQEIRQRVQAIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_SHIDS
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KCNJ6_RAT
Sequence: MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYVTSEILWGYRFTPVLTLEDGFYEVDYNSFHETHETSTPSLSAKELAELANRAELPLSWSVSSKLNQHAELETEEEEKNPEELTERNGDVANLENESKV
What is the function of this protein?
This potassium channel is controlled by G proteins.  It may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by external barium or cesium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 2, GIRK-2, BIR1, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HN_NDVB1
Sequence: MDRAVSQVALENDEREAKNTWRLIFRIAILFLTVVTLAISVASLLYSMGASTPSDLVGIPTRISRAEEKITSTLGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDYIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHSHSYQYLALGVLRTSATGRVFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKATETEEEDYNSAVPTRMVHGRLGFDGQYHEKDLDVTTLFGDWVANYPGVGGGSFIDSRVWFSVYGGLKPNSPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDGEQARLNPASAVFDSTSRSRITRVSSSSIKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGVREARSG
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: RLMN_ALKMQ
Sequence: MDKVDLLSLTMEEMESLFLEIGEKKFRAKQAFQWVNKGIKQYEEMTNLSKKLIKQLSEETRITHNRIEEKFVSKIDGTVKYLFLLDDGHIIEGVLMKYKHGFTACISTQVGCAMGCQFCASTTGGLIRNLRAGEMIDQILLMQQDQGERISNIVLMGSGEPLHNYDETIRFLKIVNDPEGLNIGNRHITLSTCGLVPEIKKLGALQIPINLAISLHAPNDQLRKQTMPIAQKYTIDQLIQSCYDYLENNNRRITFEYALIEDVNDGEKEAHELSKLLKGLLCHVNLIPINPIEERTYQKSKDSQVKKFQQILKSNGIEATIRREMGTDIQGACGQLRRKYVDDQEKKEISEV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG8_CANGA
Sequence: MAEVKEEQPKRFSLWNFWISSLLLKLLLIPDYYSTDFDVHRNWLAITNKLPLRQWYYEHTSQWTLDYPPFFAYFEWFLSQFVPSYVKSDGCLDIVEVGQFGMPTVVFQRLTVIASEILLFVVLQVYINTSKVSERTQSFVVASSIAISPGFLIIDHIHFQYNGFLFAILIASIVAAKNKKYLWCGFFYSVALCFKHIYLYLAPCYFVFLLRAYVLNLKDFKFKSYRDLIFIVKWRHLVKLGSVVIATFAVAFGPFIFDLPQLLTRLFPFSRGLTHAYWAPNFWAIYSTIDKILTMVFLKMPYTYKLASQFISPPLIPASLNEIKAKMAANNNGSKGLVEDVYFVILPQIVPKLTFLLTLLYQVLAVVPVLFDPSFKRFMGSMTLCGLASFLFGWHVHEKAIMLVIIPFSFLVISDRRLLSSFMLLTSAGYVSLFPLLYESQDFLIKTFYTYVWCVIYFFAFRKTTRLSTSVERRVFFLDRLTLVYMFLLIPMVFLIQIRDILGWKYLVLQRFEFLSLMVYSFYCSVGIISAWFGLSWLYNFDEPLWVSNE
What is the function of this protein?
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.