PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_SYNP2
Sequence: MRPRKRFGQHWLTDQQILDEIVAAANLQPTDRVLEIGPGKGALTSRLLPQVEALLSVEIDRDLCKYMVKNYGDRPNFLLLEADYLQTDINEFLGDFPQFQNPRKVVANIPYNITGPILEKLLGTIDRPNSNPFESIVLLIQKEVGDRLVAHPCTKAFGALTLRVQYLADCETVCVVPPKAFYPKPKVESVVVRLRPRPLAQPAQNPKLLATLIKVGFASKRKMLRNNLKSLYNPEILDPIFADLDISPQARGEEVDLLQWIALSDRLNDYPKE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNKS1_CAEEL
Sequence: MARRVNKKKSPVKAARKIDGQIGRRVVDGVRAKSSRQRHQAVLYQAPTPTVIRRKTTKTAIVKKTVVVVKKGGKVVKKSSKTGQKVKAVKAPKVKAPSKKGNDRLTPRVITEYQENPFFYDPQVPEYISASVYHRWITRAVRNGNMKEIKDYYKSKKCQKSAIYTSFAYSFDTSACDEALRQDIKFATEFFKMNNKMEVDNSYHPGKEPNLLQKKTTGRKNYYMLGRHTRQIEMGRGGKEGNNALLNYDTRTDEPNPLTKLIEDNVTYTKLYQLCKIPDGPIVEHHIEMHFVTAVRMGHRDLASALAQGPVKMHCNDLHRATLKDQKLPAKILPVSVAKKAYMNKNITPLHTAAISNSTHMLEAMRAVYPTINIPDQDNWYTMHYAACAPGTAPMEFLLKNGGSVTMLTKQTETPLHVAARAGRAVNCTFLMKEMLDLEKGDDGESTIRADRSIINARTRSGNSALHLAVLRNNLDVVDALLAEPTIVVDNPTSTGQNRLTPLMMACGKGYLEMAKKLVEKGALVEGKDKKKRTPLIHAMLNGQIHTAAFLLAKGASLTLADSSGNTAAHYAAAYGFLDCLKLLASIDDNILSEPNDWQLYPLSVAYLKGHYGIVTWLLEGPHKDKANINAKDNNGATLLSNLLSYADETMHKELLSQIEYLVARKADASLADSSGQTPLHLFSMQRIILKGSGEAAENDAMRMTLDNYKKCFNTLIKAGAKVDVYDHEDNTPLHYALTNGNLMLFNLMLDKVANKRNLFEKWANHQNFLHEILALPMKVYGDQVLWKGETLTKPAYDVLPILKELHENLPDLFEKWISEVNKAGYSPIVEAIKQYQALAANKKLRGEADQNGNPGFGNAIARGRVHNQFGRDRMNQSQAPHCDSYELKTFISTVNELFEWVIRLGPFQLTQKYINSENSAAVTLANLAMSIPIECGRHQQNQLALFKILIKLSKEFNKVDEFLTQKNEKDDVLIVQAIMFDKPNVVELILDTASEMHLIHGTHNAIKENELEVVVHKTIIMYMIEMRMWELIPKVNASSEFWKSKDAKGNSVWHYAARVNSHKTVGLFKMIESKGVRRETNDDGRSVLHVATLACDGSADSVLEPIAWLSTRCPIDAVDKFNRTALHYAFGNENDFKEGNVPFGESDPIAVVSLLSSLIRPEQIEIADVNGNTILHLAAIKNSTICLMTLIRKKCHVDLKNKDGNTPLALAVHHGRQSSALTLIQANADVTEKIFVPALKPTSDFDQNSSGTEAEKFWKWHGKEKKVLEDLHTTIPASVVSKGGSWEAMVYVLLDVLGQNTGSMAQLTDAALRRGQLNLANQLLKSIEALIDGAVLNSSYDLLDTFAEKCFGALTSEETIEKTVLNRIILTRGLGLKQPETMKIIRTALQNGNWNLLNFLKSEMGTAWKNQKIETPTENPIRSLLIYMNEKSVSSEAIGFLEELRQMRGVNIDALCQLEIPGKFKKILDYGLIPPISFAVLQENPNMIRALRNAGASLKTQDDYGRTPLMYAIMTNNRSVVDAIVGDGKLAVVLHKQKAVATGPRCVAVPMRFGATSRAFIPAAAFASVPARVESDEEEEDNSGSESGEDGAASENKSEHGSENGESGNGSDDEDDDDDDSSPPPAKKSRIAKEAAGPSTGPKRKKLVITDPSLFSARDHKENNPLHYFIEPLAWENVELLGDLAAANKTAIVQCLIDKRSPNPIELAAMKMNRRMKSEMLKIVKNAAFPRPIKETKLTLQQVHIEPLSDVDEDAAKFLAKWVEEKDKKKTSEAPKPHKSSTYSTNGLVSFCDETQQYFDVLMNKTDLMYGRCGFHNFYRMQIIKRRDAELFILFTNWGRIGSGMGEFQTTPFNSLELAAKEFKSIFKSKSGNEWAPLANFRDMPKKYRLVETDSTPTSLAEIELTWKKNTEKDPIRRMIADISDAKTLKTYASQVQMYGGSSQPFGRFTKENIEKAKLVLDKLEKNANRIKQMVEAQTGVVESNLLDAYITTSELSGDYYSLIPSGEYEFSNLTRLDNVEEIARHRARLNRCQEIETATRLLCAAEFRQDLDRVDYIRSAIQCEYRLETPDSDISQRLLQWIHNSGGKQAKVKMILEISPMLSTEKFEPFVNDDNQKFLWHGTKATNLMSILKNGFLIDPPSACKNGNLFGSGIYLADSFEKSTHYCQPSAGGINYMLVCQTALGKVRTLDTIPYHYMNQSSSSAEKYEDTLHYIGDRFPAGSLTNDGVGMPLLPLRKRDPIQGSNYGFGTLDFSEYIVRNPNRVLPKYIVMYK
What is the function of this protein?
Poly[ADP-ribose] polymerases modify various nuclear proteins by poly(ADP-ribosyl)ation, a post-translational modification synthesized after DNA damage that appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks and programmed cell death.
What are the official names of this protein?
Poly [ADP-ribose] polymerase tankyrase, Poly ADP-ribose metabolism enzyme 5, Protein poly-ADP-ribosyltransferase tankyrase.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with condensing chromosomes.
Protein: SIFB_SALTY
Sequence: MPITIGRGFLKSEMFSQSAISQRSFFTLLWEKIKDFFCDTQRSTADQYIKELCDVASPPDAQRLFDLFCKLYELSSPSCRGNFHFQHYKDAECQYTNLCIKDGEDIPLCIMIRQDHYYYEIMNRTVLCVDTQSAHLKRYSDINIKASTYVCEPLCCLFPERLQLSLSGGITFSVDLKNIEETLIAMAEKGNLCDWKEQERKAAISSRINLGIAQAGVTAIDDAIKNKIAAKVIENTNLKNAAFEPNYAQSSVTQIVYSCLFKNEILMNMLEESSSHGLLCLNELTEYVALQVHNSLFSEDLSSLVETTKNEAHHQS
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.
What are the official names of this protein?
Secreted effector protein SifB.
What is the protein family that this protein belongs to?
Belongs to the Sif family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. Localizes to the Salmonella-containing vacuole (SCV) at early time points following invasion and subsequently traffics away from the SCV along Salmonella-induced filaments (Sifs) in epithelial cells.
Protein: PCBP2_MOUSE
Sequence: MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS
What is the function of this protein?
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:8367306, PubMed:8208614).  Major cellular poly(rC)-binding protein (By similarity).  Binds also poly(rU) (By similarity).  Acts as a negative regulator of antiviral signaling (By similarity).  Negatively regulates cellular antiviral responses mediated by MAVS signaling (By similarity).  It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (By similarity).  Negativeley regulates the cGAS-STING pathway via interaction with CGAS, preventing the formation of liquid-like droplets in which CGAS is activated (By similarity).  Together with PCBP1, required for erythropoiesis, possibly by regulating mRNA splicing (PubMed:34180713).
What are the official names of this protein?
Poly(rC)-binding protein 2, Alpha-CP2, CTBP, CBP, Putative heterogeneous nuclear ribonucleoprotein X, hnRNP X.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: 308L_IIV6
Sequence: MLHLIKMVSKIVLLITLVFIVSAVTGSDTWVGECDYACENGKNAIDACCSQKGYAPRGYCPNGMHARCQYSVI
What are the official names of this protein?
Uncharacterized protein 308L.
Protein: COAD_LEVBA
Sequence: MTIAVFPGSFDPLTNGHVDLITRASRMFDQLIVTVGKNTSKQGLFTTSERVAFIEAAIAALPNVTVQVEQGLTVDFMKSVQATVLVRGIRNSTDFEYEQGIANLNRHLAPQVDTACLMADPQYQYVSSSLLKEVARFGGDLKQLVPSMVAKAMVARLEGDH
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_STRP1
Sequence: MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLMAKAAQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNIAVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTTLSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAITRPKEIAERFIEALKS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: HDBP1_HUMAN
Sequence: MKALGAVLLALLLFGRPGRGQTQQEEEEEDEDHGPDDYDEEDEDEVEEEETNRLPGGRSRVLLRCYTCKSLPRDERCNLTQNCSHGQTCTTLIAHGNTESGLLTTHSTWCTDSCQPITKTVEGTQVTMTCCQSSLCNVPPWQSSRVQDPTGKGAGGPRGSSETVGAALLLNLLAGLGAMGARRP
What is the function of this protein?
Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity).  Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity).  Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144).  Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738).  Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573).  Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity).
What are the official names of this protein?
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-HBP1, GPI-anchored HDL-binding protein 1, High density lipoprotein-binding protein 1.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RPOZ_ECO7I
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CLPS_STRNR
Sequence: MLAGLVPAPDHGMREEILGDRSRLIRQRGEHALIGISAGNSYFSQKNTVMLLQWAGQRFERTDVVYVDTHIDEMLIADGRSAQEAERSVKRTLKDLRRRLRRSLESVGDHAERFRVRSLSELQETPEYRAVRERTDRAFEEDAEFATACEDMVRAVVMNRPGDGVGISAEHLRAGLNYVLAEAPLFADSPGVFSVPSSVLCYHIDTPITAFLSRRETGFRAAEGQAYVVVRPQELADAA
What is the function of this protein?
Involved in the biosynthesis of albonoursin (cyclo[(alpha,beta-dehydro-Phe)-(alpha,beta-dehydro-Leu)]), an antibacterial peptide.  It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways.  Catalyzes the formation of cyclo(L-Phe-L-Leu) (cFL) as major products from L-L-phenylalanyl-tRNA(Phe) and L-leucyl-tRNA(Leu).  AlbC can also incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine and L-valine, into cyclodipeptides.  Indeed, ten possible cyclodipeptides composed of L-phenylalanine, L-leucine, L-tyrosine and L-methionine are all synthesized to detectable amounts by AlbC.
What are the official names of this protein?
Cyclo(L-leucyl-L-phenylalanyl) synthase, Cyclodipeptide synthase, CDPS.
What is the protein family that this protein belongs to?
Belongs to the CDPS family.
Protein: X_HBVC5
Sequence: MAARVCCQLDPARDVLCLRPVGAESRGRPVSGPFGALPSPSSSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQVLPKVLHKRTLGLSAMSTTDLEAYFKDCVFKDWEELGEEIRLKVFVLGGCRHNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: DB125_PONPY
Sequence: MNLLMLTFIICGLLTQVTKGSFEPQKCWKNNIGHCRRRCLDTERYILLCRNKLSCCISIIISHEYTRRPAFPVIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETITPETNTPETTMPPSETTSSKTTMPPSETATSETMPPPSQTALTHN
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 125, Defensin, beta 125.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_SYNAS
Sequence: MARITVEDALKVAGNRFALVLLAVQRSKQLLRGARPLTNVRNNREIVAALREIADNKVYFSHPEYLMGAKEDFKLIADDTTEFIGDEDYVE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SYDND_NEIM0
Sequence: MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGIVQVVIDPDTPEAFAAADSARNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVLNAAATPPFQIDDENISENVRLTNRVIDLRRPAMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALNVDLGDFPRMPYAEAMFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKEIDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIERTGAQNGDIIFFGADKTKVVNEAIGALRIKVGLEHGKDNGYFTDEWKPLWVVDFPMFEYDEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKTQRAQCLLTNAPNSVDDKQLRELSLRLRQKAAETKEA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPA12_CAEEL
Sequence: MVCCFGKKDERTKTIEKELHKERKIMRRQINLLLLGSGESGKSTFVKQMHIIHGAGEFTADEVRAYRQQIYQNAISAMRVLLDARNKLGIAWEDPKRQVEVEKVMRFSVGDLLKGIDFTTFVEVAPIISDFWNDAAIRKTYEQRNLFQISDSCQYFFEHIPRIAMPDFYPTNRDILFCRKATRGISEHIFEINKIPFRFIDVGGQRSQRQKWFQCFTDITSILFMVASNEYDQVILEDRRTNRVVESRSVFETIVNNRAFSNVSIILFMNKNDLLQEKVPKSDIRQYFTDFTGDHTLVRDVQFFLVDKFEASRRDRARPFFYHFTTAVDTENIRRVFRDVRESILEQNLKTLMMQ
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (Probable).  May play a role in resistance to fungal infection in the epidermis by regulating the up-regulation of several antimicrobial peptides of the NLP and CNC families (PubMed:22470487, PubMed:19380113).  Upstream of plc-3, tpa-1 and the p38-like pathway, required for the expression of antimicrobial peptide nlp-29 in the epidermis in response to fungal infection or physical injury (PubMed:19380113).
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-12 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: SYR_RICPU
Sequence: MNIFNQLKQDIIVASRQLYNNQEIANTATIEIPKDSFNGDLSSNVAMIIAAKESIAPREVALKFKEVLITLPYIASIEIAGPGFINFTIKADSWQASIKDILQHEEKFFEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVSYSVTKEYYVNDAGSQINDLVSTVLLRYKEALGEQITIPAGLYPGEYLIPLGQILAKEYGNKLLTMNYAERFKIVKSFAVEKMLDLNRKDLADLGIKHDIFFSEQSLHDKGEIEETVKLLERMGLIYEGTLPAPKGKIHEEWDNRVQKLFKSTKYGDSQDRPIEKADGSWSYFASDLAYAKDKIERGANHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGNFASVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELIPESYNNFESGKYDLSLLSSEEEIEIIKLLASWTKTLEASAKYFEPHRIAFYLINLASKFHSMWNFGKENSDYRFVIESNKELTLARLALASAIQKVIASGLEVIGVEPMNKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIAS_METLZ
Sequence: MRFYKIISFMLLGLDDTDSPDGMCTTYLGALIANELKRRGFTVTNHRLVRLNPNVIWKTRGNAGISLEISGGDSTVVFEIACEFVERFARFECEKTNPGVVVVESPPDPAFYYQALQRFCTIEETVKRLERIGALYKGYKNGRGLIGALAAVSSVLPDKTYECLAYRKNEVLGTPRIYAEEGFFTSEEQTAPHTWDTVDFIRREIVCVPHGKDPVLYGIRGDTPKWAIKATGFLETEEPAFSQIWETNQGTDAHLLPLPDGGPIEGESYRFSGVVESLPITNRGGHVQFTILSNGMEIPVFAFEPTKYFRNAVRELVVGDEITICGSFQKGVLHLEKFRPNLLATQKSRSSPRCPICGGRMTSAGKDKGYKCRECSGKVRDVPDQERTLQTKWYEVPPGSRRHLAKPAVRMKDDI
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS3_EXOJE
Sequence: SLDGAHAPWCDAEHRDIVNLKKSEFWNKGGPAWQKIVVCLVFDGIDPCDKNTLDLLATVGIYQDGVMKKDVDGKDTVVHIFEYTTQLSVTPNQQLIRPNDNDSTSLPPVQMIFCLKQKNSKKINSHRWLFNGFGRILNPEVCILLDAGTKPGPKSLMALWEAFYNDKDLGGACGEIHAMLGRGGVFGRKLLNPLVAA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 3, Chitin-UDP acetyl-glucosaminyl transferase 3, Class-III chitin synthase 3.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class III subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DOT1L_DICDI
Sequence: MSTNSTPRKQKLSNSKSLQNSPISPTVKKTNSFPLGNNIPTNINRSKKDKNNNSNNNINNNNSNGIGSNTIINSTPIATTPVPPLPFIHSSSSSSSSPSPSSSSSSPFPKAKKSPSLSINQQQQQQPQQPQQSPQSQQSPQSQQSQQSQQQQPQQPQEQQEPLPNLSFLRNQEPDKNVLPTSRKRPPSVMPSTPNQSSNSSSLNSSLNFSSSNSSPSPTSTQSNNSRFETRSQNDQYENNNNNNNNNNNNNNNNNNNNNNNNNIECIVIDDDDDDDDDEGNSIKSTHTSTQSTPIRDRRQRDNKWTINPLPQFQREIIDVDTPSPPNESLSIVSQTTTNTITDTTSIQTPTLIRQSSSLLSSSSSLSPSTTSTPLTQNNINLQNAQVIATMTAPMEIELPTIVQLEPLFSSEFTTSTQNLFIQTPPFTSTLTLPTTTAQTSQTLFTIQTSHDINNNNNNNNNNKNKNKNKKEIEKEKEKLREALKQKLKEYENENEKEREKERKREREIEIERERKERERKEREKERKKEKEREREREERERKEIERKEREREEREERERKEIERKETERKEIERKEIERKEIERKERERKERKEREEREEREREERERKEREEREKEIEMEREKKKEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKKRKENEVENEIEKERREKNDSYMVLNYHHSIDDHHSESESESDSDQDSIYSISTQELSSVISDNDFCDSDNEKVANNNRTVGETFLNDSRNNNNNNNNNKNNNNKKIENDKNQLIERERLISAFNDKAFLYALDTIREVLGGIDFKLKVSKEQIIEISTNAKKPLNILSEPEQQQQQQQQQQQQQHQQQQQQQQQQQQQQQQQTTKTTTTTNNTTTTTAETEKPKEVFLLKKPIKIPYGRDCKKRLIRRFHGTSRNPLFHKNLESTLKLLKRAKFDWASIEFDTKSYLMNCNCKTVCHKSERMKDNPTNKLQNNNRNNNNNNNNIINNNNNNNNKNNNNKNNNNKNNNRNNNSIAKKIGTNNNNNNTTIIKNNNNNNNNNNNNNNNNNNIIKNNNNNNKNNNNNNNTIVKKIETIKKDINKKPTKTTTTTSSSSSSTSSSNSLTVIKKPVKKINGSQRICLFEDDFDVGIGVPVTTGTSETTTTRASSIRRKMNISNIFDDFTKKPRQNKYNEIEMPDLFASKECNYTLEQQAPFIRAQKLLLTQQHENNLYNGKRFMKYDEWLDLYHGEMRSSIQNPKVLKHYISFSQEVYGEAEPTLLRHWIHLGLIKPTDVFCDIGCGIGNVLFQLAAQVGCRVIGVEIRKDLYDISQSMLEIYKKRSLELGLHPSTQQIKIYNCDVKGSLEFDFSEPNVFFMHNTCFGPELEISIMELFKKYSKPGTKVITMKTLCPRFKPSDKKTKPWGIFKYPYESYEMEEGSLSWRSATNCSFYSFTIDDKDSDIVTDQTHLNRVILSTPKKKHSKLQLFSSSSLPSSPPSSSSSSSPPNIATNTTTTTTTTTTTSPSSISLPSPYLSPSKKTPNSNKRDRSDIDNSNSDDGDENNNNININNNNNNSNNKPIKLKLSMDHSIDNQSNSESSDTDVEYMPWSKRNNRKKRKSLSYSLDSYLSSRISPSLSLSTSSSSSSSLDSSPYSSPPSSSSSDNENDDDNGDDEDDSSSSNDTKLKEKLLLMKNNEKIGGAPPLTRRNANSDTNKLVQGCYQSLSSYALPKEESQIHKLQLQAKLLEHKNSLVLKHQKSIHDQQKRLSRKQKKLAKKNKKKEQQLQAQAKTINYNNNNNNNNQNDNQVNHNNLNENEINTDLINGYNNNNNNNIINNDNDNDNDNDKDDDKDSNNKDYNNINDNNK
What is the function of this protein?
Histone methyltransferase that specifically methylates histone H3 to form H3K79me.  This methylation is required for telomere silencing, correct growth and development, and for resistance to DNA damage induced by UV LIGHT.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-79 specific, Disruptor of telomeric silencing A, Histone H3-K79 methyltransferase, H3-K79-HMTase, SAM domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VF369_IIV6
Sequence: MGIKNLTKFIKEKCQEAYVTENINELSFKKIAIDTPMYMYKYKSMNAAKMVENNGIYYNPDGWLWSFIYFIYSLRKHDIHPIFILEGGYPEEKNKTRMARKKDREDVKKKTLSLEESISSYATSLRLRPEDIPQDLKEEWNKIAKKNNLPFEDFDFETVKDHVKQRHRYDIRITNRDYEKLKILLKIMNTPFIQAPMEAEAFCAYLYKKKIIHGIASNDSDILAYGCNLIVDFEFDVKIDEETKISKITYINYDYLLNKLDLQSSEFLDFCIMCGTDYNDNIYRIGAVKSYELIKVQKCIENVGKFLDPNNKKGTILILNHLRIRHIFNHYGMKNIDDVTNMQFLEKKASWSSVPNFYLLTMLTIKFNINIDLEWIRHGFEKCNIKWDCESEYEENVEKTNVEETNNEVDEFPIF
What is the function of this protein?
Probable endonuclease.
What are the official names of this protein?
Probable RAD2-like endonuclease 369L.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: S22AD_RAT
Sequence: MAQFAQVMAEVGDFGRFQVRLTILMGIPNFLSAFFVFSQVFMVLDEAHYCSVSWVKNHTFNLSAAEQLAVSIPNDTAGRPESCLMFRPPPDNASLEDILSHRFNETQACDSGWDYPENRPPSLKNEFDLVCERENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRPSLLMQLLLSGIASMATAFVSSFELYMTLRFALATANAGFLLSSNVLLSEWVGTSRRTRAMVLAQSNFALGLMALAGLAYGVRNWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLASELLNQLVPEKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVGKFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPETRGQTLKDTLQDLEQGQPPRSYKTAPQRKDVEASGRTSSARVAVVRSSYF
What is the function of this protein?
Anion antiporter that mediates the transport of nicotinate (PubMed:35144162).  Possibly involved in nicotinate intestinal reabsorption (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 13, Organic anion transporter 10, OAT10, Organic cation transporter-like 3, ORCTL-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: Y1166_ENT38
Sequence: MKTKLNELLEFPTSFTYKVMGQALPELVDQVVEVVQRHAPGDYSPTVKPSSKGNYHSVSITITATHIEQVETLYEELGNIDIVRMVL
What are the official names of this protein?
UPF0250 protein Ent638_1166.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: 457L_IIV6
Sequence: MQNFMVLLLLIVAVVAIMFVLPKNNKTLLHHMRRRRRELKDLLKSKKIIGAKNLMEFVKKYTQIDKTCAYEGPIPMPAEFSTMSADNLQLLDKCGAVRSSLNSWAIATWAENSVVKTMENLQSTMECVNQLNLVPDTYNRFQELVTACFSAVPPPPPKNPNNISNLPIGVYGSPYGIYGMNYNLGTSYQGVTNGFVSDSRGWRPDDYFNYNAQGSELIDGTNTLMTAQMLQQYELPRIGFGPYMSRSEIDAEVLPKYEPSQWIVNNGPVRPWEPKYPIMTIPPTPIPLLGTSNM
What are the official names of this protein?
Uncharacterized protein 457L.