PharMolix/UniProtQA huggingface dataset:
Protein: CTL4_BOVIN
Sequence: MGGKQDQDKEAYGKPAKYDPSFRGPIRNRSCTDIICCVLFFLFILGYIAVGILAWVYGDPKQVLYPRNSTGAYCGIGENKEKPYLLYFNIFSCVLNTNIIAIAQNGLKCPTPQVCVSSCPEASWTVEPRQFSQTVEQVFYAANRNFCLPGVPGNMQVLQSLQQELCPSFLLPSTPALGRCFPWTNSTVPELPGISNTSISQSISGLLDSLNARDISVKIFEDFAQSWYWILIALGLALVLSLLFILLLRLVAGPLVFVLIIGVLGVLAYGIYHCWEEYRVLRDKGASISQLGFTTNLSAYRNVQETWLAALIILAVLEGVLLLMLIFLRQRICIAIALLKEASRAVGYIMSTMFYPLVTFALLLVCIAYWAIIALFLATSGQPQYVFWAPNSSLPGCEKVPMNTSCDPMEQVNSSCPGLMCVFQGYQSTGLAQRSLFNLQIYAVLGLFWTINWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLGSAFLRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGAQNPLTRCILCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFTGRIPSLGKTFENPQLNYYWLPIMVSILGAYLIASGFFSVFGMCVDTLFLCFLEDLERNDGSADRPYYMSKSLLKILGKKNKGTPGDKKRKK
What is the function of this protein?
Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity).  Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity).
What are the official names of this protein?
Choline transporter-like protein 4, Solute carrier family 44 member 4, Thiamine pyrophosphate transporter 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Apical cell membrane.
Protein: COX3_PARLI
Sequence: MMAHQHPYYLVEQSPWPLTGAISGLMMNLGLVLWFHTGNIILLFTGLLLLILTLVNWWRDIVREATFQGSHTAIVENGLRYPMILFITSEVCFFFAFFWAFFHSSLAPAVEIGVTWPPSGITPLNPFLVPLLNTAVLLSSGVTITWSHHSILAGNRNEAIQALFLTVVLGIYFTILQAWEYIDAPFTIADSVYGSTFFVATGFHGLHVIIGTTFLLVCLIRLSGHHFSTHHHFGFEAAAWYWHFVDVVWLFLYVCIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLMM_AZOVD
Sequence: MNSLLLHCRPGFEGEVCAEIGEHAGRLNVAGYARAKPNSAHAEFVCSEPGGAERLMRELRFAGLVFPRQWARGAFVELPESERIGVLLEHLAAYPVCGSLWLEVLDSNEGKELSTFCRKFEVPLRKALGKTGRLLDDPRRPRLLLTFRSGREVFLGLAEPDNSAAWPMGIPRLKFPREAPSRSTLKLEEAWHQFIPREAWDLRLAPGMSAVDLGAAPGGWTWQLVNRHMKVTAVDNGPMAQSLMDSGLVEHVRADGFVFRPRRPVDWMVCDIVEKPARTAALIETWLGEGLCREAVVNLKLPMKQRHAEVRRLLERIRDGLSARGAKVSVACRQLYHDREEVTCHLCRLPAPA
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUD19_RAT
Sequence: MSGPSSWRRAATVMLAAGWSHASPAGFRLLLLQRAQNQRFMPGAHVFPGGVLDAADSSPDWVSLFAPRHTPPRFGLGPEPPRQPSFPGLFHGDADGAALPDDVALRICAIRETFEEAGVLLLRPRDSARASQEPSIALSPPAGLADWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGRSSRRFDTTFLLCCLRETPRVEPDLAEVVGYKWLSPSEATECFLSKEIWLAPPQFYEVRRLENFASLSALYRFCLDHPLEVPEKWLPIVLLTSDGSIHLLPGDELYVKGSDFLEKNMSIDKKTEEIVTEGKVVNRIVIHSPHLYEIYMTLTSKSEHGYPKSYTAKKSCTARL
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).  Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase NUDT19, Nucleoside diphosphate-linked moiety X motif 19, Nudix motif 19.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ATG29_YEAST
Sequence: MIMNSTNTVVYIKVKGRRPQGFLDPPKFEWNGTKERQLWTMVSNLNYSQDQIDWQNLSKIFETPEFFLKKRTYKLFAEHLELLQLQLEKKRDLEKYSNDQVNEGMSDLIHKYTPTLQNDNLLNVSASPLTTERQDSEEVETEVTNEALQHLQTSKILNIHKKTSDSENKPNDKLDKDGINKEMECGSSDDDLSSSLSVSKSALEEALMDRLQF
What is the function of this protein?
Plays a role in autophagy.  Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions.  Also plays a role in mitophagy and regulation of filamentous growth.
What are the official names of this protein?
Autophagy-related protein 29.
What is the protein family that this protein belongs to?
Belongs to the ATG29 family.
What are the subcellular locations of this protein?
Preautophagosomal structure. Note=Localizes also to other perivacuolar punctate structures.
Protein: P2RY4_CRIGR
Sequence: SDTLYVLSLPTLVYYYAARNHWPFGTGFCKFVRFLFYWNLYCSVLFLTCISVHRYMGICHPLRALRWGRPRFASLLCLAVWLVVAGCLVPNLFFVTTSPNGTTILCHDTTRPEEFDHYVHFSSAVMVLLFGLPFLVTLVCYGLMARRLYRPLPGAGQSSSRLRSL
What is the function of this protein?
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
P2Y purinoceptor 4, P2Y4, P2Y4 metabotropic purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_PSYCK
Sequence: MAIKLIVGLGNPGQEYMFTRHNAGFWFVLHLAQQFNITLAPDKKFHGVTGRGQIHGHDVRLLMPLTFMNKSGQSVVPMVKFYGIDNDELLIAHDELDIPAGSIKLKTDGGHGGHNGLRDITPHIGNDFHRLRVGIGHPGHKSKVSGHVLSKAAPDEQIAIDSALSAAFDALPLLLGGDVEKARSQINGFKLPE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP2_LACBS
Sequence: MFTLAHHRHAIRKPMAEFFGVALLVIFGAGAACQVVLSTNPNSFLSINFGWAIGIAMGAWISGSISGGHINPAITIAMATYRGFPWREVPSYILAQVLGGVVGAALVYANYIHAIDVFEGGRHIRTQATASLFATYALPYMTQVSCFFSEFLATAVLAMMVLALTDNRNGAPTNGLSPFALFVLFIGLGASLGMETAYALNPARDFGPRLFLAMAGYGKALFNYRSQYWLWAPIIAPVLGAQAGGLLYDTFLYDGDDSPIKWR
What is the function of this protein?
Probable water channel required to facilitate the transport of water across membranes.
What are the official names of this protein?
Aquaporin Lacbi1:233199.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: PURQ_PROMA
Sequence: MTIGIVVFPGSNCDRDVHWATQGCLGMSTRFLWHESTDLNGLEAVVLPGGFSYGDYLRCGAIARFAPVLSSLLEFVNKGGKVLGICNGFQILTELGLLPGALTRNQELHFICDTVPLLISSQRTQWFKNYNQSKNIFLPIAHGEGRYQCSESILKKLQDEDSIALKYKNNPNGSINDIAAITNKSGNVLGMMPHPERAADKDIGGIDGIKILQALLSN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROK1_EMENI
Sequence: MDAFKLLTRSTKLKSATTQSSTLPSTGKAANPQLFRGAAAEKLEKGSGKKRKRAHAADDEAVVNEDALNLDFFSQGRSSIPKSSDAATTKGSGAPAGQEGASESDSDADDEPMDEVQRRTILNAHKIKVTDMRDLEELAPAQVQSEEPKKKKKRKQQEEAEKQQPQTLSKKEQKKARRLFPQPLVSFKELRSKYKISRRLAENIAEQGFTVPTEVQLGSLPLLLGNSAVPGGSSDSTSATEPDLLVVAPTGSGKTLSFMIPVINKIVRHHHTHPEERGIFAVVVAPTKELASQIVNEGRKLALGTGVKVTLMKKGMRVVERENEDEDVLDESNSESSESESDERTPNNKNKGPVPITKSDILVSTPLQLVNALSDNKTKPLATLPLVRNLVLDEADVLLDPLFRDQTLDIWRSCTHPELRASLWSATMGSSIEDMAKTTIKERKLSLPQTKSYPLLRLVVGLKDSAIPNIKHKLVYAATEQGKLLGLRQLIHPTAATTSDVRLRPPFLIFTQTIPRAIALHSELLYDIPPEAGGSARIAVLHSDLSDTQRSDIMKGFRKGEIWILVTTDLLARGVDFRGINGVVNYDIPNSPAVYVHRVGRTGRAGREGGVAVTYYTKEDIPYVKSIANIIDVSEKLRGENGERSVQKWLLDALPDLSKKNKKELKKHGVKARQTGLKGATDEKEQRRTRISTKSGFDRRKEYNKKMMIAASQKKTQARKNGADSDSAGDDDDEDGWNGLDD
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase rok1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PXP1_YEAST
Sequence: MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGEKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAFAWQNKPRL
What is the function of this protein?
Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
What are the official names of this protein?
Putative 2-hydroxyacyl-CoA lyase, Peroxisomal protein 1.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome matrix.
Protein: BAMB_ECOLI
Sequence: MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDGLVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPTTAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
What is the function of this protein?
Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins.  Efficient substrate folding and insertion into the outer membrane requires all 5 subunits (PubMed:20378773, PubMed:21823654, PubMed:27686148).  A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins (PubMed:27686148, PubMed:26900875, PubMed:26901871).
What are the official names of this protein?
Outer membrane protein assembly factor BamB.
What is the protein family that this protein belongs to?
Belongs to the BamB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: AGALC_ASPTN
Sequence: MVAFMNSATFVAGLFTLWSRPIWATPASNTNAVVVNGTAFTLNGDHVSYRFHVDDATGDLFSDHFGPRVSGNFPTEIVSQVNGWVNTIGRVRREFPDQGRGDFRIPAIRIRQTAGYTVSELLYRSHTVIPGKPALPGLPATFGSEEDVTTLVVHLYDEISEVAADLSYSIFPKYDAVVRSVNVTNQGAGNITIETLASLSVDFPYEDLDMVYLRGDWAREAHSERRKVEYGTQGFDSSAGYSSHLHNPFLAIMNPATTESQGETWGFSLVYSGSFAVNVERGSQGFTRALLGLNPGQLSWVLRPGESLVSPECVAVYSADGIGGMSRLLHRLYRNHLIKSKFAVSDRPVLLNSWEGLGFNYNETTVYQLATEAAELGVKLFVLDDGWFGDKYPRTADNAGLGDWVPNPDRFPHGLPHEVDRITALHPGNDTSTNLRFGLWFEPEMVNPNSSLYHQHPDWALHAGSYPRTLTRNQLVLNMALPEVQDYVIKSVSDILDSADISYVKWDNNRGIHETPSPSTDHQYMLGMYRVFDNLTTKYPNVLWEGCASGGGRFDPGVLQYFPQIWTSDDTDALERITIQMGTSLAYPPSAMGAHLSAVPNQQTGRTLPITFRAHVAMMGGSFGLELNPAHMPDDERDAVPGLIALAERVNPIVLTGDMYRLSPHDSQWPAVLFISPDGEQAVLFYFQTSPRVDNSIPRVKMQGLDPQAVYSVDGDAEYSGATLMNVGLQFPFDSDVGSKVVFFQRL
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
What are the official names of this protein?
Probable alpha-galactosidase C, Melibiase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YJJB_SALA4
Sequence: MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGALGHGSRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSIP_DICDI
Sequence: MFIQRTFLKVLTLLSIVTVLVHGQTQPKDKITLKAVIYDQHKFYNPNFQPKNEGEFVLTKGIVKSDIDQEKRIPVLNSMDANDSINKKARISWPDGFKYFFVDNQAGDSKSAKSGKNLPIQRDIELNWNGEAYEYSNSNYFPINGQGFNDVSYPVPRGYVPISGESWTSMSTSTSLKGNNYNFCLKLNSKFTYNGNEVFKFTGDDDVWVYINNKLVVDIGGIHSQVSASVDVTKLGLTVGTIYNFDFFYCERKTSESNIKIQTTIETYCAYVDYCGVCEGDGSTCCNPATTCNDGKRCTNDFCPDPKSPLAGKDISKYCDHIPVKTCSSKDTLCKQYTCSDDLKGDMCVIKNTVTCPGNQTNCEASGYCDDKFGCINPSKCTDYIGQCFSGKCVNGECAKVTADDCEKIIGGVCRSDYVCEPGLGCKSSERCRQGSDICDLVTCDPKATDESKRCITTVLTDEECRCCEYDTLRFCEQAACSNKTGLCQPIPKNVDDGNLCTIDACNEDEKTITHVQVTCGGCETCSYATGKCEPDSSLCNDNNICTIDICVHEGILDGLPQGNCSNTPVDCGANDEDKCKTWSCDPTKGGCQSTPVVCEDKGKCLVGTCQPSTGQCEYSDRVCDNGGAFCVIGQCDQRLGCLVFDRVCSSDNSRCEEGVCVNGTESEEGHCKSVKYDPLPFNCNTGAVVSTAVIAGSTVAGAVALGIFLYGGKKGYDYWKDSRNISMGSSNSNPLYEEQQTGRGVNPMYDDPAAN
What are the official names of this protein?
Protein psiP.
What is the protein family that this protein belongs to?
Belongs to the prespore-cell-inducing factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PURA2_RICCO
Sequence: MSFTSSLRLDTNPITSPKWVHRQVPLRPHRNFVVCSIKSPSTPSLNLATDSASTDSLSRINSLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILNEDTLCVIGNGVVVHLPGLFKEIDGLESSGVSCTGRILVSDRAHLLFDFHQEVDGLREAELAKSFIGTTRRGIGPCYASKAIRNGIRVSDLRHMDTFPQKLDILLSDAASRFQGFKYGPEMLREEVEKYKRYAERLEPFIADTVHVMNESIEQKKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRAVGDLIGVVKAYTTRVGSGPFPTEILGQGGDLLRFAGQEFGTTTGRPRRCGWLDIVALKYCCQINGFSSLNLTKLDVLSDLPEIQLGVAYKHADGTPFKSFPADLRLLEQLKVEYEVLPGWKSDISSIRNYADFPKAAQQYVERIEELVGVPVHYIGVGPGRDALIYK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 2, chloroplastic, AMPSase 2, AdSS 2, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECA_PROM1
Sequence: MSNEGKPLQSTESTKIDAKSGEKEKALSLVVGQIERNFGKGSIMRLGDASKMRVETISTGALTLDLALGGGYPKGRVIEVYGPESSGKTTLTLHAIAEIQRNGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLIRSAAVDLVVVDSVAALTPRSEIEGEMGDHSVGAQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGITYGNPETTTGGNALKFYASVRLDIRRIQTLKRGTEEYGIRAKVKVAKNKVAPPFRIAEFDILFGKGISTLGCLLDLADETNVVTRKGAWYSYEGDNIGQGRDNTITWLEQNPESKEIIEKLVKEKLTEGSEVSANSMRPLASAARQASSRPKLSQVSANG
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HROB_HUMAN
Sequence: MACSLQKLFAVEEEFEDEDFLSAVEDAENRFTGSLPVNAGRLRPVSSRPQETVQAQSSRLLLLHPTAPSEALGLPDLDLCLPASSTPSADSRPSCIGAAPLRPVSTSSSWIGNQRRVTVTEVLRETARPQSSALHPLLTFESQQQQVGGFEGPEQDEFDKVLASMELEEPGMELECGVSSEAIPILPAQQREGSVLAKKARVVDLSGSCQKGPVPAIHKAGIMSAQDESLDPVIQCRTPRPPLRPGAVGHLPVPTALTVPTQQLHWEVCPQRSPVQALQPLQAARGTIQSSPQNRFPCQPFQSPSSWLSGKAHLPRPRTPNSSCSTPSRTSSGLFPRIPLQPQAPVSSIGSPVGTPKGPQGALQTPIVTNHLVQLVTAASRTPQQPTHPSTRAKTRRFPGPAGILPHQQSGRSLEDIMVSAPQTPTHGALAKFQTEIVASSQASVEEDFGRGPWLTMKSTLGLDERDPSCFLCTYSIVMVLRKQAALKQLPRNKVPNMAVMIKSLTRSTMDASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSFLKPSQPFPKDSGSFQHDVAAKPEEGFRTAQNLEAEASPEEELPEADDLDGLLSELPEDFFCGTSS
What is the function of this protein?
DNA-binding protein involved in homologous recombination that acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis.
What are the official names of this protein?
Homologous recombination OB-fold protein.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localized to the sites of DNA damage.
Protein: NUDL_KLEP7
Sequence: MADRALNLDDFLSRFQLLRPQPSRHALNQRQAAVLVPIVRRPQPGLLLTQRSPLLRKHAGQVAFPGGAVDNTDATLIAAALREAQEEVAIPPEAVEVIGVLPPVDSVTGFQVTPVVGIIPPDLHYHASQDEVSAVFEMPLAEALRLGRYHPLDIHRRGNDHRVWLSWYQHYFVWGMTAGIIRELALQIGARP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: PGK_PROM3
Sequence: MAKRSLSSLSAADLRSKRVLVRVDFNVPLNENGAITDDTRIRAALPTINDLIDKGARVILSAHFGRPKGQINEGMRLTPVAKRLSELLGKTVIKTESCVGSDAEAKVNAMADGDVVLLENVRFFSEEEKNDANFAQKLAALADAYVNDAFGAAHRAHASTEGVTKFLNPSVAGHLMEKELQYLQGAIDDPKRPLAAIVGGSKVSSKIGVLEALIDKCDKVLIGGGMIFTFYKARGLSVGKSLVEEDKLELAKELEAKAKAKGVQLLLPTDVVLADDFSPDANSQTVSIDAIPDGWMGLDIGPDSINLFQDALADCQTVIWNGPMGVFEFDKFAAGTNAIATTLADLSGKGCCTIIGGGDSVAAVEKAGLAEKMSHISTGGGASLELLEGKVLPGVAALDDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMIG1_BOVIN
Sequence: MAQKTSGLIQRCRFLLLMILFLPHVMTSSVLSVNGKTENYILDTEPGLQESLKCAVQNHIRDEELLWYREDGRVDLKSGNKINSSSVCVSGISEDDNGITFTCKLQRNQSVSISVVLNVTFPPLLSGNDFQTAEEGSDVKLVCNVKSNPQAQMMWYKNNGILNLENHHQIQQTSEYFQLSITKVKKSDNGTYSCIANSLIETKTKDFHLIVKDKGSTVPIEPIIAACVVVFLTLVFGVIARRKRIMKLCRKDQGPQCRTAL
What is the function of this protein?
May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.
What are the official names of this protein?
Transmembrane and immunoglobulin domain-containing protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: SECB_SHEON
Sequence: MAEVANNEQQAPQFNIQRVYTKDVSFETPNSPAVFQKEWNPEVKLDLDTRSAKLADDVYEVVLSLTVTAQNGGETAFLCEVQQAGIFSIAGLTEPQLAHSLGAYCPNILFPYAREAVGSLVGRGTFPQLNLAPVNFDALFAQYVQQRQAAAAEEANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_AZOVD
Sequence: MALADRLLEAWYRGHPALVLLRPLEALFRCVAQRRRERFLRGEGGIYRAPVPVVVVGNVTVGGTGKTPLILWLIEACRRRGLRVGVVSRGYGARPPRLPWRVTADQSAGQAGDEPLLIVQRTGVPLAIDPDRPRAVRALLKEQPLDLILSDDGLQHYRLARDLELVLLDAVRGLGNGHCLPAGPLREPAERLASVDAVLHNGAAWDPPGGYAFSLLPSALVHMATGERRPLDHFPPGTALHALAGIGNPRRFFATLEALHWRPIPHAFADHARYRAEQLRFSPALPLVMTEKDAVKCRAFAPADCWYLAVDAVPSPAFADWFDAALARLLASS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SAFA_ECOL5
Sequence: MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: YOP1_ASPFU
Sequence: MASFQDRAQHTIAQLDKELSKYPVLNNLERQTSVPKVYVILGLVGIYTFLVFFNIAGEFLVNFAGFLIPGYYSLNALFTSGKADDTQWLTYWVVYALLTVVESAINAAYWFPFYYIFKFVLILWMSLPQTNGAQVVFHSFLQPVLGRFFTSGSTSANLRAQADAASKSQ
What is the function of this protein?
Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole.  Induces high curvature in membranes and causes membrane tubule formation.  Involved in membrane/vesicle trafficking.
What are the official names of this protein?
Protein yop1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.