PharMolix/UniProtQA huggingface dataset:
Protein: M1249_ASFK5
Sequence: MEEVITIAQIVHRGTDILSLNNEEIEALVDEIYSTLKGSNDIKNIRLIDFLFSLKDFVNHVRAEQSKLPDLSMPMEAYIRQLLVNPDVVPIVSEKKKELRVRPSTRKEIFLINGTHLAVPAEVPIEIYGLKLRLKTFSPQCFMRMAEIGSFSPETLGYVASGANLTNFIRVFMKCVDQETWKKNGEGVVVTTKENIIQFTHQYIELYKFLRSGGHSWLINRLAEEMVHRKLDRENQGSHISSIIETEEVEPEEENIKRVIFFLKELSTMYSVFPVFTSGYMPLLYDLYRAGYLEVLWNPVEQKFLQHAEQREKEQMILQQVDMKLTEVTTQARQYFKIMEEKIGRVQSDTIREILTMEGKVDDPSSILQEVIKACGKQEAELITTEYLNIKKQWELQEKNACAHLKLVKQLRSGLQYAESLKVLESIRVLYKEKNNTTNWNLCKACGFKLLCPHVDMLIQLQAAEASYDTMRTKLMKFSGINKEKENNQGLIYSYFCKICGEELAHFIQEDRTADVGVIGDLNSKLRIFIWQETMKACTFIHFGKLVDVKQFANIAVNVCLPLIYSIENIKKEEDYDPLTQLYAVIYIYAYILNLIYSSQKNKEFLTITIHGMKADSSLNAYVTFLLEKMTQQYSGIINQLSEITDQWIANNFREAFKKIIHQNGLQGLSVQDDTKVLLTEILLDPLYDYAATVARIDGSIPMHKPRTPKEAEYEFKTVIGRTPAELLSQKEFYDKIYTSKYRPDFTQLARLNDVYFQEESLRVWWGGRDEEKISTLIYLRAYELFLKYLQNAPNFNSELAEFKKYENAYGEQKALLAQQGFYNIFDPNTGKADQRTRLFEYKKLPISTLYDEKGLPHKWTIYVYKAIDSSQKPAEIEVSRKDVIKKIDNHYALADLRCSVCHVLQHEVGQLNIKKVQTALKASLEFNTFYAFYESRCPKGGLHDFQDKKCIKCGLFTYIIYDHLSQPELVHDYYNNYKDQYEKEKMSIHSIQIKKDIAVPPTETQPKPQQKPWTFDYGKIIKTAKILDISPAVVEAIGAMEGRSYADIKEGQGAPPPPTSMDDPRLMAVDSAVRIFLYNYNCLRHISTFNKPPMHIERLVKHLSYEEKEDLEKVLPNVVNEYHTTFKQLRVTDPASALLYSIEFLCISFLTLYEIKEPSWVVNIVREFALTELNTIIQSEKLLSKPGAFNFMIFGEDFVCSGEDSSMDDISAYSSPGLFGEDIIDRLDDPFSIEDVDISLDVLDNLAPQ
What is the function of this protein?
Together with the penton and the other minor capsid proteins (p17, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid.  In addition, blocks IFN-beta transactivation mediated by the cGAS-STING pathway and regulates the transcriptional activity of IFN-beta.  Mechanistically, suppresses the phosphorylation of host key adapter protein TBK1 and degrades host IRF3 in the cyltoplasm.
What are the official names of this protein?
Minor capsid protein M1249L, pM1249L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus M1249L family.
What are the subcellular locations of this protein?
Virion.
Protein: SYH_HAES1
Sequence: MAKTIQAIRGMNDCSPTESLLWQWVEEKVRSVLQTYGYSEVRMPIVESTPLFARAIGEVTDVVSKEMYTFWDNDEQLTLRPEGTAGCVRAAIEHGWIYNNEQRLWYMGPMFRHERPQKGRYRQFHQAGVEVFGIANPEIDAELILLTARLWKQLGIFDHVTLQLNSIGSLESRQNYRSALVEFLQQHTDLLSEEEKERLVKNPLRILDTKNQVLQEVLNDAPKLLDYLDQESREHFSQLCDLLDAVGIQYEINPKLVRGLDYYNKTVFEWVTSALGAQGTVCGGGRYDGLVEQLGGHATCSVGFAMGLERLVLLVQEVNKQIVLPSAVDIYVVYFGEKTTLPAFQLAEKIRTELPHLRTMTHCGGGNFKKQFKRADKVGAKFALVIGETEVKTQQVVVKDLLGGAEQLSLALTDVVIYLKQAITQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAE2_XANOP
Sequence: MSWDDAIEGVDRDTPGGRMPRAWNVAARLRAANDDISHAHVADGVPTYAELHCLSDFSFLRGASSAEQLFARAQHCGYSALAITDECSLAGIVRGLEASRVTGVRLIVGSEFTLIDGTRFVLLVENAHGYPQVCGLVTTARRAASKGAYRLGRADVEAQFRDVAPGVFALWLPGVQPQAEQGAWLQQVFGERAFLAVELHREQDDGARLQVLQALAQQLGMTAVASGDVHMAQRRERIVQDTLTAIRHTLPLAECGAHLFRNGERHLRTRRALGNIYPDALLQAAVALAQRCTFDISKISYTYPRELVPEGHTPTSYLRQLTEAGIRKRWPGGITAKVREDIEKELALIALKKYEAFFLTVQDVVRFAREQNILCQGRGSSANSAVCYALGITAVNPDETRLLMARFLSEKRDEPPDIDVDFEHERREEVLQYVYRKYGRERAALAATVICYRGKSAVRDVAKAFGLPPDQIALLANCYGWGNGETPMEQRIEEAGFDLANPLINKILLVTEHLRDHPRHLSQHVGGFVISDEPLSLLVPVENAAMADRTIIQWDKDDLETMKLLKVDCLALGMLTCIRKTLDLVRGHRGRDYSIATLPGEDLPTYKMIQRADTVGVFQIESRAQMAMLPRLKPAEFYDLVIEVAIVRPGPIQGDMVHPYLRRRQGREDVSYPSPAVEDILKPTLGVPLFQEQVMELLMHAADYTESEADNLRRSMAAWRRGGDMEQHRTRVRERMQGKGYASTFIDQIFEQIKGFGSYGFPQSHAASFAKLVYASCWLKRHEPAAFACGLLNAQPMGFYSASQIVQDARRGSPERERVEVLPVDVVHSDWDNTLVGGRPWRSAADPGEQPAIRLGMRQVAGLSDVVAQRIVAARTQRAFADIGDLCLRAALDEKARLALAEAGALQGMVGNRNAARWAMAGVEARRPLLPGSPEERPVAFEAPHAGEEILADYRSVGLSLRQHPMALLRPQMRQRRILGLRDLQGRPHGSGVHVAGLVTQRQRPATAKGTIFVTLEDEHGMINVIVWSHLALRRRRALLESRLLAVRGRWERVDGVEHLIAGDLHDLSDLLGDMQLPSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IR10_HCMVM
Sequence: MYPRVMHAVCFLALGLISYVAVCAENTVTTNCLVKAENTHLTCKCNPNTTSNTNNGSKCHAMCKCRVTEPITMLGAYSAWGAGSFVATLIVLLVVFFVIYAREEEKNNTGTEVDQCLAYRSLTRKKLEQHAAKKQNIYERIPYRPSRQNDNSPLIEPTGTDDEEDEDDDV
What are the official names of this protein?
Protein IRL10, TRL10.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 RL10 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: NING_BP933
Sequence: MAKPARRKCKICKEWFHPAFSNQWWCCPEHGTQLALERRSKEREKAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIKQAQQAVNAFIRERDRDLPCISCGTLTSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELINRIGQEAVDEIESNHNRHRWTVEECRAIKAKYQQKLKDLRNSRSEAA
What are the official names of this protein?
Protein ninG.
What is the protein family that this protein belongs to?
Belongs to the ninG family.
Protein: DADD_METMP
Sequence: MILVKDAIITGKKQDLLVEGNIIKKIGNISISEVSKDETEIIDGKNCVLIPGLINTHTHVPMSLFRGVADDIPLMEWLSGHIWPMESKLNEKIVYAGTLLGTIEMIKSGTTAFNDMYFFLDSIIKAVDETGIRSTIAYGMIDLFDEEKREKELKTAKESLEMIKNLNNSRITGALGPHAPYTCSKEILESTNALAREYNVPIHIHMNETLDEINQVVEKTGMRPFEYLNSFGFFDNVNTICAHCVHLSASEIQIMKEKNIFAAHNPVSNLKLASGVSPVLKLLENNIPVTLGTDGCGSNNNMNLFEEIKAAALIHKGVNLNPVAVIAKDAFDFGTKNGAKALNINSGEIKEGKLADFVLINMKKPYLTPKENIESHLVYSFNGVVDKVVIDGKLVLNDGKMVNIDEEKVYEIAEEAYFELAN
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: Y273_METTH
Sequence: MNLKTHAFNDRGRIPSRYTCDGENISPPLSWDGVPGEAKSLALICDDPDAPSKVWTHWVIFNIPPDSTGLEENVPDAGRLPDGSVQGYNDSGTLGYRGPCPPSGVHRYFFRLYALDTVLDLEPGASKEDVLEAMEGHVLGEAKLIGLYRRG
What are the official names of this protein?
UPF0098 protein MTH_273.
What is the protein family that this protein belongs to?
Belongs to the UPF0098 family.
Protein: CYSK_BUCAP
Sequence: MNKIYEDNSFTIGNTPLVRLNNIGNGNILAKIESRNPSFSVKCRIGANMIWDAEKKGRLNKNIEIIEATSGNTGIALAYVAAARNYSLTLIMPDSMSIERRKLLKSLGAHLILTNGKHGMKGAISKANEIVSLNTKRYLLLKQFENPANPEIHQKTTGPEIWKDTKGNIDILISGVGTGGTITGITKYIKIKEGKKDLISVAVEPLESPVITQFLSGKKIKPGLHKIQGIGAGFIPKNLDLSLIDRIITVSSEEAIFNAKKIMKKEGILSGISSGAAIAAALKIQKENDFKNKNIVVILPSSGERYLSTELFSRSFKNENNY
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: UVRB_DESVV
Sequence: MADTCFRLHTEFEPTGDQPEAIGQIVANLGQGVRDQVLLGVTGSGKTFTVANVIAACNRPALILAPNKTLAAQLYNEFRALFPDNAVEYFVSYYDYYQPEAYVPASDTYIEKDSSINDNIDKLRHAATHALLTRRDVVIVASVSCIYGLGSPEYYARLVIPVECGQRFSMDALMTRLVEVQYQRNDFDFHRGTFRVRGDVLEVIPAYHHERALRIEFFGDDIDAISEIDPLTGEVLGSVGKTVIYPASHYVSDRDNLVRAMSDIRDELGERLREYQSANRLVEAQRLEQRTMLDLEMMEELGYCNGIENYSRHLDGRAAGQPPSCLLDYFPDDFLLFVDESHITVPQVGAMYKGDRSRKSTLVDFGFRLPSALDNRPLEFAEFLTRINQTVYVSATPGKWELDRSQGVIAEQIIRPTGLVDPVVEVRPTRGQVDDLLAECRARAARDERVLITTLTKRMAEDLTEHLGNMGLSVRYLHSDIDTMERMAIIQALRRGECDVLVGINLLREGLDIPEVSLVSILDADKEGFLRSTGSLIQTFGRAARNAAGRVILYADTVTASMRAAMDETARRRERQQAWNEANGIEPRTIRKSLDTPFDAIYSAASEGGKGRGRGRGRQAAPAVENVAEYGTSPEDMAKHIQKLEREMREAAKELEFERAATLRDRIRLLRERLIEA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYF_STAPU
Sequence: MQNKDACKSLSSWVSLSISLLVLTVPLIWPYNSTAFPIYAQQNYESPREATGRIVCANCHLAKKAVDIEVPQAVLPDTVFEAVVKIPYDTQIKQVLSNGKKGGLNVGAVLILPEGFELAPSDRIPPELKEKISNIYFQPYSPEKKNILVVGPLPGNKYSELVFPILSPDPATNKKASFLKYPIYLGGNRGRGQVYPDGSKSNNNVFSASTAGTISQITRQKKGGYEVIIKTTDGREVTDIIPPGPELIVSEGESIKADQLLTNNPNVGGFGQADAEIVLQDPLRIQGLLVFFASVILAQIFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: O168_CONVE
Sequence: MKLTCMMIVAVLFLTAWTFVTADSRNGLEYLFPKAHYEMNPEASKLNKKRDCVAGGHFCGFPKIGGPCCSGWCFFVCA
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like VnMKLT1-0111.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHL1_NEOFI
Sequence: MGSQPQNFNHPYSPYDIQLQFMRALYTCLEEGKVAVFESPTGTGKSLSLICGSMTWLREHKRKALQDTVNKASCSAGDDDGEPEWMLEFAKRESARAVTEKRRALEARLEKIKVEEEKQRHAHATDHPGEARKRQRLDTSSGDPGQEQDDQFILDDYDSDAEERITYSKKLGDISGLSTSTLELLERFKEQFSASAEDETGHEDDDVKIFYCSRTHSQLSQFSSELRRVKMPSSMPAELSTSDANTDDAEERVKHLTLGSRKNLCINPKVMSLGNATAINERCLELQQPGVAAEKRCPYLPSKEDEGQVLQFRDHTLATIKDIEDMGKLGKRMGICPYYASRSVLKHSEIVTLPYPLLLQRSARDALDLSIKNHVVIIDEAHNLMDAICNIHSVTITLSQLQTALSQLTTYARKHKARLKGKNRSYIAQIIRLISSIADHLRSTIGENLPAEGAVDPSDLMAGKGVDQINPYKLSRYLQESKLARKVDGYVEFSKDKNQQSDDKPSSPVLFLVQSFLLPLMNPSAEGRFFYLKFHDDIQLKYMLLDPTNHFREIVEDARAVILAGGTMSPMSDYRNHLFSYIAPSRLDTFSYGHVIPPENLIAHTLVNGVLGSEFDFTYDSRDSEKMILDLGRTVAMLCQAIPDGVVAFFPSYDYLSRILAIWRKPLVGEKGQTILSLIERKKSILYEGRDMGAKTEDLLQEYTRTIDSGQGALLLSVVGGKLSEGINFSDKLGRGVLIIGLPFPNIRSAVWQAKIQYVEQKTYNSSSGSEKDRLSIAKAAGKDFYENACMRAVNQCIGRAIRHRNDYAAIVMIDRRYEKANIQGKLPAWIKQSMLRRSVRRPASALAADLSNFFSGRSSG
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase chl1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATG1_PICAN
Sequence: MSKHQTQVVGDFTIGPEIGRGSFANVYKGYDNRTKAPVAVKSVFRSRLKNQKLVENLEIEISILKNLKNPHIVALLDCVKTDQYFHLFMEYCSLGDLSYFIRRRDQLVQTHPLISSILERYPSPPNSHGLNKVLVVNFLKQLASALEFLRDQNLVHRDIKPQNLLLSPPVHSKEEFKRKGYSGLWELPVLKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVIYEMSVGKPPFRASNHVELLRKIEKSKDEITFPVSAEVPDDLVRLICGLLKANPTERMGFQEFFNDPLIVYDVQCADEPLECSNVDEQLFISEYLPNLKTSPPAKPAPETIKEESEEEERAERAPTDSLLIGKEADLRIPRPMEGSGKDEVIKKLINKSSPPPDTVKDGQIKKGARRDKDDFVYEKDYVVVEKRTVEVNAIADELAKAGAGAVAIPSPHLGTNEHSAANPSGPTETQTQRRFSPSSRTSSIGSNRRPSWGDRKMPISISPTNALTKALGYTSNRLFGQQQQQPQQAQQAAIESAITNVTTNLLATKTLRPLKPSQETSLEDTEVINQLELLATMAHAISLFAEVKFSQLIPLPPSSSSPGSADYDEMYQNDAFPPQMVKSISSEGVALYVETLSLLAKAMSIASDWWHQNSSKPSTSPKLNDLVQWIRSRFNESLEKAEFLRLRLADANEQLVGESGSSLNKPVVAEKLIFDRALEMSRTAAMNELKNEDLLGCELSYSTAIWMLEALLSNDEEPVTGNEKLDAEDKKIIELFINSIGNRLKVLRQKIDKQGVRS
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes (PubMed:12702243).  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1, Peroxisome degradation deficient protein 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: COMGC_HALH5
Sequence: MKKPFHHQAGFTLVEMMIVLMIISILLLVALPSMTKNNEVAGDKGCEATVKLLQTQVHAYEIDHDRLPTNLDALKREGYVEHTECPNGKKLTLRNGVVAISE
What is the function of this protein?
Required for transformation and DNA binding.
What are the official names of this protein?
ComG operon protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the ComGC family.
Protein: KDSB_SHEPC
Sequence: MNVILLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKATVEGFGGKVVMTSPDAASGTDRINEAIKLLGLKDDDLVINVQGDQPLIDPTAIEQLINLFERQPGEFEMATLGYEIVNKADIDDPMQVKMVFDNNYYALYFSRSRIPFGRDTQDYPVFKHLGIYAYTSKFVQTFAALPLGRLEDLEKLEQLRALEHGHKIKIAISASNSLEVDRPEDIHKCEQRLAAS
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_EHRRW
Sequence: MKIDLNTIFPSSRKEYIPGKIYKNIKIGMRKVSFNNDTESIFIYDTGGPHSDQDIQTNINNGIKKLRLNWITDRQDVEYYDRHTINTNSSTAFPLQNNKALKSKSDKPVTQMFYAKNNIITPEMEYVAIRENSLIQKLLSHTPNTIIPEITPELVRQEVAAGRAIIPANINHPESEPMIIGKNFLVKINANIGNSAVSSDINNEVHKMIYAIIYGADTVMDLSTGSHIHNTREWIIRNSPVPIGTVPIYQALNKVNGIVGELDFNIFKETLIEQAEQGVDYFTIHAGVLKKYIQYTTNRLTGIVSRGGAIIAQWCSIHNKENFLYTNFEEICDIMKSYDIAFSLGDGLRPGSIADANDKAQFLELKTLGELTDIAWKHDCQVMIEGPGHVPMHLIKENVEKQIYFCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTSMLCYVTPKEHLGLPNLNDVKNGVITYKIAAHAADLAKGNPSAYIRDYALSHARFNFRWYDQFNLSLDPETAKSFHDESLPSEHAKSAHFCSMCGPKFCSMKLTHQLQLNSTE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: YMF14_MARPO
Sequence: MICFIFTYKDFIIKMSTFWQNLWLIYLFIVFYVLGMSFVVWLLLRSASIKNFIYTLVAGVAEAAAQATQTELNYHACKRYTKACNDADIPVNPHKIEELTTPRGGTGRN
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf14, ORF109.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DPFF1_CAEEL
Sequence: MISENGYMDLMRNCIKWNSRQMEDRKKRLRFPYYEHQTATAQRESRFTTRNVDHMYPSNDPNTVVQFATERWKKSKSQPPSDAVEMSMFLRENPSIQVAIDHLTPQVVGPTTESVSDSSNDSTTIRPSRQTQIKEEYRDDYVLDDELSPDEFGSDEDDWSSRKRRKGNLGPVQKATSSRKKVPTTRSSVSRLTPSRSIVKETKYEEPEEKTYPCDKCSAKYKSLAGLSYHQSYLHDQKSSQPLVKLLSPSIEISTSCDFCSGTAFMNKNTKLPEDLVSCHDCGRSGHPSCLNFNQNVTKIIKRSGWQCLECKSCTICGTSENDDKLLFCDDCDRGYHLYCLTPALEKAPDDEYSCRLCQVEFGDKASAPAKK
What is the function of this protein?
Probable transcription factor, involved in meiosis and stress protection.
What are the official names of this protein?
Zinc finger protein dpff-1.
What is the protein family that this protein belongs to?
Belongs to the requiem/DPF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Expressed at higher level in nuclei.
Protein: CITG_ECOBW
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What is the function of this protein?
Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.
What are the official names of this protein?
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: PDC1_MAIZE
Sequence: METLLAGNPANGVAKPTCNGVGALPVANSHAIIATPAAAAATLAPAGATLGRHLARRLVQIGASDVFAVPGDFNLTLLDYLIAEPGLTLVGCCNELNAGYAADGYARSRGVGACAVTFTVGGLSVLNAIAGAYSENLPVVCIVGGPNSNDYGTNRILHHTIGLPDFSQELRCFQTITCYQAIINNLDDAHEQIDTAIATALRESKPVYISVSCNLAGLSHPTFSRDPVPMFISPRLSNKANLEYAVEAAADFLNKAVKPVMVGGPKIRVAKAREAFAAVADASGYPFAVMPAAKGLVPEHHPRFIGTYWGAVSTTFCAEIVESADAYLFAGPIFNDYSSVGYSLLLKREKAVIVQPDRMVVGDGPAFGCILMPEFLRALAKRLRRNTTAYDNYRRIFVPDREPPNGKPNEPLRVNVLFKHIKGMLSGDSAVVAETGDSWFNCQKLRLPEGCGYEFQMQYGSIGWSVGATLGYAQAAKDKRVIACIGDGSFQVTAQDVSTMLRCGQKSIIFLINNGGYTIEVEIHDGPYNVIKNWDYTGLVNAIHNSEGNCWTMKVRTEEQLKEAIATVTGAKKDCLCFIEVIVHKDDTSKELLEWGSRVSAANSRPPNPQ
What are the official names of this protein?
Pyruvate decarboxylase 1, PDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: TUSA_SERP5
Sequence: MTDLFAQADQTLDALGLRCPEPVMMVRKTVRHMDNGETLLIIADDPATTRDIPGFCRFMEHTLVAQETDTAPYRYLLRKGV
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5438_BURM7
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAHEGQNRLAVAIDARSSASLDEMPGLIRALSHEHDVRVLFLNASTQALIQRFSETRRRHPLSGSPSHDADVGLLVSLEEAIERERELVAPLAEFGHQIDTSNLRANVLRTWVKRFIEQKNDDLVLMFESFGFKRGVPLDADFMFDVRALPNPYYDHELRPLTGLDQPVVAFLDALPVVHQMLDDIETFLVKWLPHFREDNRSYLTVAIGCTGGQHRSVFLAETLAARLSRQASVIVRHRDAPVAVDASSRLVT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BMA10247_2938.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SCX32_RHOJU
Sequence: KEGYPMGRDGCKISCVINNNFCKVECQAKWRQSDGYCYFWGLSCYCTIYQKTPRFGILAPINVEDNVTVTQCLGHLINVMYSH
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Putative beta-neurotoxin RjAa32.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_MYCPA
Sequence: MTPADLAELLRNTAAAVLAERGLDAAALPATVVVERPRNPEHGDYASNLALQLGKKVGANPRELAGWLAAALAETDGIASAEVAGPGFINLRLEASAQAVVVTNVLDAGDRYGHSDAQSTHNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAGVVREYYFNDHGAQIDRFASSLIAAAKGEPTPEDGYAGSYINDIAAQVLRQAPDALSLPEPQLRETFRAIGVDLMFTHIKESLHEFGTDFDVYTHEDSMHTSGRVDQAIARLRETGNIYEKDGATWLRTSAFGDDKDRVVIKSDGKPAYIAGDIAYYLDKRQRGFDLCIYMLGADHHGYIARLKAVAAAFGDDPATVEVLIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAAELGLIPDTAHLELLSHDKEGTLLRTLGEFPRVLKTAASLREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEQPTDLHTARLALCQATRQVIANGLAILGVTAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGCL_RAT
Sequence: MATVRKAFPQRLVGLASLRAASTSSMGTLPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQATCKL
What is the function of this protein?
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis.  Terminal step in leucine catabolism.  Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
What are the official names of this protein?
Hydroxymethylglutaryl-CoA lyase, mitochondrial, HL, HMG-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Peroxisome. Note=Unprocessed form is peroxisomal.
Protein: RS20_PEDPA
Sequence: MPVIKSAMKRVRTSEKAAARNRSQMSAMRTSIKAFEIAATNNAENANELLQTAYSRIDRAKSKGLIKANNAGRKKSRLAKMLSK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.