PharMolix/UniProtQA huggingface dataset:
Protein: TRMN6_SHIB3
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWLTQQTVRFDLIISNPPYYQQGVECAIPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_RHIL3
Sequence: MTARMDKRFAELKAEGRPALVTYFMGGDPDYDTSLGIMKALPEAGSDIIELGMPFSDPMADGPAIQLAGQRALKGGQTLKKTLQLAADFRKTNDATPIVMMGYYNPIYIYGVEKFLDDALLAGIDGLIVVDLPPEMDDELCIPAIRKGINFIRLATPTTDEKRLPKVLKNTSGFVYYVSMNGITGSALPDPSLVSGAVERIKQHTKLPVCVGFGVKTAEHAKVIGGSADGVVVGTAIVNQVATSLTHDGKATADTVQAVATLVRGLSTGTRSARLVAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TRPF_XANCB
Sequence: MNRSLYRTRIKFCGMTRAGDIRLAGELGVDAVGFIFAHGSPRRVAPAEARAMRQATAPMVDVVALFRNNSKEEVREVVRTVRPTLLQFHGEEDDAFCRSFNLPYLKAVPMGASGVNGEDANARTLQLAYPNTAGFLFDSHAPGEGGGTGKTFDWSRLPTGLHRPFLLAGGITADNVFDAIVATLPWGVDVSSGVELAPGIKDGHKMRKFVEEVRRADCHEMS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: PX11A_RAT
Sequence: MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTKLKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTVLWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSSGDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNLGVVGFGGLVSSVAGLITVVYPQLKLKAR
What is the function of this protein?
May be involved in peroxisomal proliferation and may regulate peroxisomes division.  May mediate binding of coatomer proteins to the peroxisomal membrane (PubMed:9548716).  Promotes membrane protrusion and elongation on the peroxisomal surface.
What are the official names of this protein?
Peroxisomal membrane protein 11A, 28 kDa peroxisomal integral membrane protein, PMP28, Peroxin-11A, Peroxisomal biogenesis factor 11A, Peroxisomal coatomer receptor, Peroxisomal membrane protein 26, Pmp26p, Protein PEX11 homolog alpha, PEX11-alpha, RnPEX11p.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: RPO10_PYRAR
Sequence: MIIPVRCFTCGKPLGHLYAVFKQRVLAGEHPGKVLDDLGLVRYCCRRTLMAHVEWIDDVLIYEKR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_TREPS
Sequence: MGYPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATDIYCRYLRMGGYNVLHPMGFDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYDWEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINWCPSCKTGLANEEVRDACCERCGAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAPACSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHAQRAAVQAYVQRAAKKNDLERTDLAKEKTGVFTGAYVRNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFATRFGLPKLTVVSADYTATVPNSNSPQGAVLQRCVSDEGFVVNSGAFNGLASADARERIVAHLEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVPLPESALPLLLPETADFTPTEDGQGPLARARTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEKERYWAPVALYVGGAEHAVLHLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRKNGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALKNVVNPDDMIAAYGADACRVYEMFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSCSMYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILSPYAPHLAEELWEMCGHTHTIAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAPNEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_SODGM
Sequence: MIRITDAAQEHFAKLLSNQEPGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTELKFDKISAYVDELSAPYLQDAEIDFVTDKLGSQLTLKAPNAKMRKVSDEAPLIERVEYLLQSQINPQLAGHGGQVTLMEITDDMLAILQFGGGCNGCSMVDYTLKEGIEKELLEKFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: EFTU_LEGPC
Sequence: MAKEKFERKKPHVNVGTIGHVDHGKTTLTAAITTIMAKKYGGTAKAYDQIDAAPEERERGITISTAHVEYESASRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKADMVDDPELLELVEMEVRDLLSSYDFPGDDIPIVVGSALKALEGEDSDIGVKAIEKLVETMDSYIPEPVRNIDKPFLLPIEDVFSISGRGTVVTGRVESGIVKVGEEVEIVGIRDTQKTTCTGVEMFRKLLDEGRAGDNVGVLLRGTKRDEVERGQVLAKPGTIKPHTKFEAEVYVLSKEEGGRHTPFFNGYRPQFYFRTTDVTGTCDLPSGVEMVMPGDNVQLVVSLHAPIAMDEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_XYLF2
Sequence: MGHKVHPIGIRLGISADWNSKWYANKAEFARYLAADLKVRQVLRKKMSQAGISKILIERPSNTACVSMHVARPGVVIGKRGEDIEMLRKQVSDIMGVPVHINVIEVRKPELDAQLVAESVAQQLERRIMFRRAMKRSVSNAIRLGALGIKISVAGRLNGAEIARSEWYREGRVPLQTLRADIGYGFSEAYTNYGVTGVKVLMYHGDIFSFSSVSQEKQDDGSRGDRNADRSSRRSREVR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GBA2_RAT
Sequence: MVTCVPASEQIGCAERDSQIYSEDTGGTEAVRVTDCRSPEDSGPQNEPGYCNSEDSGQLMASYEGKARGYQVPPFGWRICLAHEFAEKRKPFQANNVSLSNLVKHFGMGLRYLKWWYRKTQVEKKTPFIDMFNSVPLRQIYGCPLGGIGGGTITRGWRGQFCRWQLNPGMYQHQTVIADQFIVCLRRDGRTVYQQVLSLELPSVLRSWNWGLCGYFAFYHALYPRAWTVYQLPGQNVTLTCRQITPILPHDYQDSSLPVGVFVWDVENEGDETLDVSIMFSMRNGLGGEDDAAGGLWNEPFRLEQDGTTVQGLLLHHPTPPNPYTMAVAARHTADTTVTYTTAFDPDSTGQQVWQDLLQDGQLDSPAGQSTPTQRGEGVAGAVCASSKLLPRGRCCLEFSLAWDMPRIMFGAKGQVHYRRYTRFFGSDGDVAPALSHYALCQYAGWENSISAWQNPVLDDRSLPAWYKSALFNELYFLADGGTVWLEVPEDSLPEELGGSMYQLRPILQDYGRFGYLEGQEYRMYNTYDVHFYASFALVMLWPKLELSLQYDMALATFKEDLTRRRYLMSGVVAPVKRRNVIPHDIGDPDDEPWLRVNAYLIHDTADWKDLNLKFVLQVYRDYYLTGDQGFLKDMWPVCLAVMESEMKFDKDQDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAVLCGAQDVQDKFSSILCRGREAYERLLWNGRYYNYDSSSQPQSRSVMSDQCAGQWFLRACGLGEGDTEVFPTLHVVRALKTIFELNVQAFAGGAMGAVNGMQPHGVPDRSSVQSDEVWVGVVYGLAATMIQEGLTWEGFRTAEGCYRTVWERLGLAFQTPEAYCQQRVFRSLAYMRPLSIWAMQLALQQQQHKKNSSRPAVTQGTAPSQPECGPKRSL
What is the function of this protein?
Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramides/GlcCers (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) to free glucose and ceramides (such as N-acylsphing-4-enine) (By similarity).  GlcCers are membrane glycosphingolipids that have a wide intracellular distribution (By similarity).  They are the main precursors of more complex glycosphingolipids that play a role in cellular growth, differentiation, adhesion, signaling, cytoskeletal dynamics and membrane properties (By similarity).  Involved in the transglucosylation of cholesterol, transfers glucose from GlcCer to cholesterol, thereby modifying its water solubility and biological properties (By similarity).  Under specific conditions, may catalyze the reverse reaction, transferring glucose from cholesteryl-3-beta-D-glucoside to ceramide (such as N-acylsphing-4-enine).  May play a role in the metabolism of bile acids.  Able to hydrolyze bile acid 3-O-glucosides as well as to produce bile acid-glucose conjugates thanks to a bile acid glucosyl transferase activity.  Catalyzes the hydrolysis of galactosylceramides/GalCers (such as beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine), as well as the galactosyl transfer between GalCers and cholesterol in vitro with lower activity compared with their activity against GlcCers (By similarity).
What are the official names of this protein?
Non-lysosomal glucosylceramidase, NLGase, Beta-glucocerebrosidase 2, Beta-glucosidase 2, Bile acid beta-glucosidase GBA2, Bile acid glucosyl transferase GBA2, Cholesterol glucosyltransferase GBA2, Cholesteryl-beta-glucosidase GBA2, Glucosylceramidase 2, Non-lysosomal cholesterol glycosyltransferase, Non-lysosomal galactosylceramidase, Non-lysosomal glycosylceramidase.
What is the protein family that this protein belongs to?
Belongs to the non-lysosomal glucosylceramidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localization to the plasma membrane and alternative topologies have also been reported.
Protein: SLAF8_MOUSE
Sequence: MWSLWSLLLFEALLPVVVVSVQVLSKVGDSELLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLKPGDSGNFSVLMVDTGGQTWTQTLYLKVYDAVPKPEVQVFTAAAEETQPLNTCQVFLSCWAPNISDITYSWRWEGTVDFNGEVRSHFSNGQVLSVSLGLGDKDVAFTCIASNPVSWDMTTVTPWESCHHEAASGKASYKDVLLVVVPITLFLILAGLFGAWHHGLCSGKKKDACTDGVLPETENALV
What is the function of this protein?
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
What are the official names of this protein?
SLAM family member 8, B-lymphocyte activator macrophage expressed.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS1_ECO57
Sequence: MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
What is the function of this protein?
Required for translation of most natural mRNAs except for leaderless mRNA.  Binds mRNA upstream of the Shine-Dalgarno (SD) sequence and helps it bind to the 30S ribosomal subunit; acts as an RNA chaperone to unfold structured mRNA on the ribosome but is not essential for mRNAs with strong SDs and little 5'-UTR structure, thus it may help fine-tune which mRNAs that are translated.  Unwinds dsRNA by binding to transiently formed ssRNA regions; binds about 10 nucleotides.  Has a preference for polypyrimidine tracts.  Negatively autoregulates its own translation.
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: PYRFE_NOSS1
Sequence: MIFFDKLHQNISQNQSLLFVGLDPNPEMMPGRYSSQDIIDGLWDWLQFIIAETADFVCAYKPTLGFYEALGVPGLELLQKTLAAIPSHIPIILDAKHSDLNTSTIFAKTVFTQWGVDAITLSPYTGQDHVAPFLVYPDKAVFILCSTSNPGAEALQQYPTRESPLYLQVVQESKNWGTPEQLGLEVGTTNAEVLARIRQVAPERMIMVRSIWAEGGNLNRILEVGLNTDGNGLLIPVPQDMLASANLSKEIQSLRAEINQVRDITVRDVASCSVWLPDVFTVKQHPLHDLILQLYDIDCIMFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYGSLPTATGLALRLNCPMIFPRKEVKAHGTRRLIEGNFRTGEVVVVVDDILISGKSVMEGADKLKSAGLNVHDIVVFIDHEQGVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTAE
What is the function of this protein?
Catalyzes the decarboxylation of orotidine monophosphate (OMP) to uridine monophosphate (UMP).
What are the official names of this protein?
Bifunctional enzyme PyrF/PyrE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: AROA_MARMS
Sequence: MNSITLGPLSKANGEIQIPGSKSLSNRILLLATLAKGTTKITNLLDSDDIRRMLESLTKLGVSYSLEDNGTTCVLEGLGGPIQADFGDLFLGNAGTAMRPLTAALCLGKGEFLLHGEPRMHERPIGDLVDALQALGVDITYEGEKNYPPLRIKANGLSGGEVSIKGNISSQFLTAILMSAPLAKSDLTIKVDGELVSKPYIDITLHAMKQFGVEVENQNYQAFVVKGQQTYQSPGEIMVEGDASSASYFLAAAAIAGGKIKVHGVGTDSVQGDVKFADVLAQMGAKITYGPSWIEAERNELNGIDMDMNHIPDAAMTIATTALFAKGPTTIRNIYNWRVKETDRLYAMATELKKLGADVIEGKDFITVTPVANLKHAAIDTYNDHRIAMCFSLVAFSDTPVTINDPGCTSKTFPTYFELFNTIAN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAS_SHESH
Sequence: MPVKIPDDLPAAEILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESRHTSIDHMNNFYRDFEAVRHKNYDGLIITGAPLGQVEFEDVSYWDHIREIIDWSQQHVTSVLFLCWAAHAALFHLYGLNRKLLKEKRSGVFLHKRTHRHVPLLRGFDDEFLAPHSRFAEMDVQLLKAHPALQVLTESDEAGAYMVLSTNNRNLFVMGHPEYQKSTLKDEYFRDLGAGLQPEIPQNYFRHNDPGQDPVARWYGHGSLLISNWLNYYVYQLTPYNLDDMSGITPWENEV
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ROSCS
Sequence: MALEKDEKTAIITDYQIHSSDTGSPQVQVALLTERINGLIEHLKVHPHDHHSRRGLLKLVGRRRRLLAYLASKDKDAYRKLIDSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HBEAG_HBVB4
Sequence: MQLFHLCLIISCSCPTVQASKLCLGWLWGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: RECF_BIFLS
Sequence: MHISRLALDHYRSWSQVVVDFVPGVNILFGKNGLGKTNLVEAVEVLSTGSSHRTSSTLPLIERGQTTATIRANVADDAGQTTTYEASIHARGANRARINSGSSLYLRDIIGKIPSVSFTPEDQRLVSGDPGARRTMMNQAAALLEPGYMQTLQQFTRIAKQRATLLKQLNANANNGQPMDAVLSGLEIWTGQFIEAGVVLTRMRAHVISLLAEPFAAIYADLAGAGEQVTLTYAPSFDEVLMFNDPHPQISEHFQRIYPGEVARGVNLIGPQRDDMNLDLAGIPAREFASNGEMWTMALALKMALFEIVRDRLGLQPIVILDDVFAQLDDSRRAQILDFARKQDQVLITVAAEGDVPDYESAHRIDVAALAEPASVILPTLGNLSDLRENESLGKYDGKTAVDSASVERKVS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU2_CAUSK
Sequence: MAKEKFERNKPHCNIGTIGHVDHGKTTLTAAITIILAKSGGATAKNYADIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVYMNKVDLVDDEELLELVEMEVRELLSSYDFPGDDIPITKGSAKVAIDGGDPVIGEQSILALMTTVDAYIPQPDRPIDLPFLMPVEDVFSISGRGTVVTGRIEKGVVKVGEEVEIVGIRAVQKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVERGQVLCKPGSITPHTKFVAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIIKLREGVEMIMPGDNAELDVELITPIAMDQGLRFAIREGGRTVGAGVVAKIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_PEDPA
Sequence: MELISLFKQYLTVERQYSEKTVTAYLEDIDAFQKFLTDTGDKTDLLLVDRFDVNVYMSYLFDRHLARTSISRKVSALRSFYRFLVKNDLVDKNPFELVQLKKQSDKLPHFFYEKEMNMLFEAVYQAEGAQKLRNIAILEVLYGTGMRVSECAALQWSDIDFSMQTILVLGKGNKERYVPFGRYAKEALQNYRKNEWEPFLSKYKQTHNFVFINHYAKPITTTGIEYILNQVITASSLNGKIHPHMLRHSFATALLNNGADLRTVQELLGHSSLSTTQIYTHVTKEKLQESYRKYFPRSTDA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO03_BPHC1
Sequence: MAYTYKMVQVPPNIIANRKNITTAAADYLQDVVNEWAENGWEFWRIDNFSTEEKAGCLSGGKLTMRTYKVITFRKEV
What are the official names of this protein?
Uncharacterized 8.9 kDa protein in int-C1 intergenic region, ORF17, ORF3.
Protein: SMC6_CAEEL
Sequence: MGKRDIPSPNENIAPRTIGMRDVDLTAAPAKKAKLDTGERIAVSGRVASVKLTNFMCHANLQIDFKTAQNNCFYIGGPNGSGKSALFAAINLGLGGRGSDNDRGNTVKSYIKDGTTQSKITITLTNAGLNAHPDFDDLISIERTINQASSTYIMKSVKVTSSDNHVERIVSRKKADVDRIVSRFSIHLSNPAFWMSQDRSRSFLANFKPANVYKLYLESTNLENIRLSYIRFADALDECFALIQLKAGEILNEQKKLKRMQEQRDLQAKLDQDRALVASFCWKLLFCKVRDYNDQIELTLKKQEAQKTLQDETKKEYAKNRAARTEVEKKIQEFRDEVEVQDAEIAEAREDLDAKKRKVLEFEEKIRECEQSIRKKTSEKKYMERTIVNAKNEVRILLEKQGNQDLTKRLTKVENDYKDISQQRENMELGGESAKLREKLDTVITDYKRKEEEKYTIQRDINQLRRKIEQDMETMRRSRATKKDAINKFGSHMAEILMEINRSKSRFQTVPKGPLGKYITLIDPKWAFTVEECIGNLANNFLCSSHLDAEILRNIFQSLRIPAQDRPTIIVAKCNGRAYTNLHEPSSDFKSIYRVLKFSDPDVHNVIIDKSNCEQFILIEDKTEAMELMGSNYPPQNAVKAYTLDGSQAYANGPNSQYRFYSGRGGHARGTFGNDQGDVDEGALARLIEDTKSEAMRLETQDLRKQDHELKVIYNERDQTKAAIDEFDRKLSNLRSQELQKERQAKDLRAELAQTANEDQVENLNESIEEMQKKIPLIEDEVKDILKNVADITADMAPVIQERKEAEHTLAEIQKETRDFASKSQKLQNELSKYDDAGEILKIRLDKVKADEGVFFHTEAKLKSERDDAMEMVENDKKNHPMPPGETDPPDLSSFPSTTEAQRKIEEMQKAVDRATVGCDTTITLECVKDFKDKLKRLKYLCRMIEDVLIELKNLHAARVKAYPSLKKFTELKVCNKFQELLAVRGHFIGGLEFDHEKETLNVNVQSSKEKDAMAGRRPEVLEVEEVDEHSYDDDSDDSTGPRRKKSKKSGQKKKRVRDLKGLSGGERSFVTAALVMSLWEVMEQPFRMMDEFDVFMDMMNRKLVMDLLVELATKKFPHNQFIFFTPQGIKELNMVDGLQVFEMNRVRD
What is the function of this protein?
Core component of the smc-5/smc-6 complex (PubMed:20661436).  Involved in DNA double-strand break repair by promoting sister-chromatid homologous recombination during meiosis (PubMed:20661436, PubMed:24939994, PubMed:27010650).  Also plays a role in the DNA damage repair of ultraviolet (UV) radiation-induced DNA lesions (PubMed:24424777).  Promotes efficient DNA replication (PubMed:24424777).
What are the official names of this protein?
Structural maintenance of chromosomes protein 6 homolog smc-6.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Nucleoplasmic in the distal gonad arm and localizes on chromosomes during pachytene, diplotene and diakinesis in oocytes.
Protein: ILVD_SALG2
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNCNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRSAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLNEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PIMT_VIBVY
Sequence: MSNPQAERLVHFLAVNGIRDSEVLSAIARVPRECFLSQAMMHQAYDNNALPIGQGQTISQPYIVAKMTELLRLKRDSKVLEIGTGSGYQTAVLALLVEHVYSVERIKSLQWDAKRRLKQLDIYNVSTKHGDGWLGWENKGPFDAIIVTAAAESVPPVLLQQLNDGGRMVLPVGTDEQQLILIERQKDQFVSQVIEAVNFVPLIAGDLA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_PECCP
Sequence: MQFAKMHGLGNDFMVVDAVTQNVYFSPELIRRLADRHCGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIAVSTQTGRMVLSVTDDELVRVNMGEPNFEPQQVPFRAVKAEKTYIMRADEHTVLCGVVSMGNPHCVIQVEDVDTAKVETLGPLLESHERFPERANIGFMQVVDSHTVRLRVYERGAGETQACGSGACAAVAVGIQQGLLSANVRVSLPGGDLDIQWDGPGHPLFMTGPATHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.