PharMolix/UniProtQA huggingface dataset:
Protein: R35A2_ARATH
Sequence: MKGRQGERVRLYVRGTVLGYKRSKSNQYPNTSLIQIEGVNTQEEVNWYKGKRLAYIYKAKTKKNGSHYRCIWGKVTRPHGNSGVVRSKFTSNLPPKSMGARVRVFMYPSNI
What are the official names of this protein?
60S ribosomal protein L35a-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
Protein: COAX_BURVG
Sequence: MSAPHLLIDAGNSRIKWALADAQRTLVASGAFGHTRDGGADPDWSALPHPQGAWISNVAGADVAARLDALLDAQWPALPRTTIRARAAQCGVTNGYTSPEQLGSDRWAGLIGARAAFPDEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPTLSTDIASGLLADARAEPFQIDTPRSLSAGCLYAQAGLIERACRDLAAAWQAPVRLVLAGGAADDVARALTLPHTRHDGLILSGLALIAAEGAARD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C14C3_ORYSJ
Sequence: MEKLLALIVVLVILLSLALFYLCNILWLRAVKIRKKLRRQGIRGPKPTFLYGNTKEIKRIRQELKLSQKQGTNNFISTLFPHFLLWRETYGPVFLYSTGAMEILQVSHPDMVKDIGRWTPSELGKPNYLKKSRKALFGGGLFTENGDEWAYQRKIIAPEFFMDKIKGMIQLIEDATVPVLEAWEDMIDDEGGCREIVVDDYLRNLSADVIARACFGSSFTKGEEIFCKLRQLQKAIARQDSFVGLSALWKYLPTKSSQEIQMLDEQVRLLILDVAKEQHHYQDSHNSLVNAIIDGAQDGRSAAEAEDFIVGNCKTIYFGGHESTAVTAIWCLMLLATHPEWQERARAEAMEVCRGRSTLDVDALRRLKIVTMVIQETLRLYPPASVMMREALTDVKLGSIEVPRGTIVQVPRLMLHLDKEAWGADADEFRPDRFANGVAAACRAAHMYVPFGHGPRTCIGQNLAMAELKVVLARLLTKFAFSPSPRYRHSPAFRLTIEPGFGLPLMVTKLP
What are the official names of this protein?
Cytochrome P450 714C3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: INSI2_PIG
Sequence: MAEGETKSPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATLVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2.  Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi.  Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2.  Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase RNF139.
What are the official names of this protein?
Insulin-induced gene 2 protein, INSIG-2.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL27_CLOPS
Sequence: MLKMNLQLFAHKKGVGSSKNGRDSEAKRLGVKCADGQFVLAGNILVRQRGTKIHPGANVGKGGDDTLFAKIDGVVKYERLGRDKKKASVYPVNVEEVIAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: BIOF_ANAD2
Sequence: MARGALDWIGAELEALDAKGLRRSLEPIGPAQGPVVQVGGRALVNLCSNDYLGLAADPRVRAAAADAAMRFGAGSGAARLVAGDLPPHGALEARLAAWKGREAALLFGSGYHANAGVPGALVGRDDAVFSDVLNHASIVDGCLLSRAELVRYRHCDVEELAGLLARTRARRKLVVTDAIFSMDGDAAPLRELAELCDRHGAMLYVDEAHAAGVLGPNGAGLAEALGVQDRVDVHMGTLGKALGAFGAYVAGERRLIELLVSRARPFVFSTALPPPACAAALAALEVVATEPSRRTHLFALCARMQAGLARLGFDVARVASPIFPVVLGTEARALAAAAALRERGWFVRAIRPPTVPHGTSRLRVALSAAHDAAQVDGFLAALAAVLPDLPPAGPRRAG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: NUOB_POLSJ
Sequence: MSLEGVFNEGFMTTSYDSVVNWAKTGSLWPMTFGLACCAVEMMHAGAARYDMDRFGMLFRPSPRQSDLMIVAGTLCNKMGPALRKVYDQMSEPRWVLSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQQKIRRTNTIARA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLMM_PARPJ
Sequence: MARRYFGTDGIRGKVGEGPITPEFVLRLGYAAGKVLAGADRWAKSGTRPTVLIGKDTRVSGYMLEAALESGFSAAGVDVMLAGPMPTPGIAYLTRALRLAAGVVISASHNPYYDNGIKFFSADGNKLPDEVESQIEEQLDLPLACAASEQLGKARRLDDAAGRYIEFCKSTFPAAFDLHGLKLVVDCAHGAAYDVAPHVFHELGAEVIPIGVAPNGFNINDGVGATAPDALVRAVRANHADLGIALDGDADRLQVVDAAGRLYNGDELLYILVKDRVATDGKVDGAVGTLMTNMAVEVALQEAGVKFVRAAVGDRYVLEQLREHGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAAMKRSEKTLADLLDGVTLFPQKLINVRMKPDADWKSSDAIRRAIAKAESALNGRGRVLIRASGTEPVLRVMVEAENAADALQYAESIAGAVKEATA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SHUT_ADECR
Sequence: MSEEPVSGTTVEIEEDTHTPPNSPVLETFSLSPEPEAEACPNTDRYLSANLLCKHLQRQSAIVLDSIKDQLQVPTSVSELSCAYERSLLCPNIPPKQQSNGTCEANPKLNFYPTFLVPETLATYHIFFVNQKIPVSCKANRAKADKALTLQEGDCLPDYETMDTVSRVFEGLGGEVVAENALQNNDSVLVELKEDNPRLAVLKRNLSVSHFAYPAVHLPPKIITTVMNNLLVKRANPSADVSELDPDGGQEVVSDTELSRWLNTSDPETLEKQRKLVMGSVLVTVVLECMQRLFTSKDMVKKIGETLHYTFRHGYVSLACKISNVELTNVVTYMGILHENRLGQTTLHHTIQGETRRDYIRDSIFLILIHTWQTAMGIWQQCLEEENLKELAKLVQKIKKPLYTETSQRLMGKQLANVVFPPKLLETFNKGLPDIVNQSMMQNFRSFILERSGILPSMTCALPTDFIPIHFKECPPTMWPYTYLLRLANFFMYHNDLCYDMEGEGLLEHYCRCNLCTPHRCLATNPAMLNETQLIGTFDIRGPGGENGAESSSGLKLTAGMWTSAFLRKFESSDYHAHKIHFYENQSKPPSVEPTPCVITQSSILAQLHDIKKAREEFLLKKGQGQYLDPHTGEPLNAAGPSVESGHEFQGDGRHREPKRGRHFRQRGGPRKPPRAHAGGEPDVRGTTS
What is the function of this protein?
Protein that inhibits host translation while promoting late viral translation by ribosome shunting.  Blocks host cap-dependent translation by binding to eIF4G, displacing MKNK1 from cap initiation complexes and preventing EIF4E phosphorylation.  Binds to the tripartite leader sequence of viral late mRNAs and recruits host eIF4G, PABPC1/poly-A binding protein and 40S ribosomes subunits on viral mRNAs, allowing ribosome shunting and efficient translation of late viral mRNAs even though conventional translation via ribosome scanning from the cap has been shut off in the host cell.  During assembly, acts as a chaperone protein that helps hexon proteins assembly into trimers.
What are the official names of this protein?
Shutoff protein, 100 kDa protein, p100K, 100K-chaperone protein, L4-100K, Shutoff protein 100K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae shutoff protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SYL_METPP
Sequence: MSTPHPAPASAYEPGAIEAAAHAHWTARDAHRVVEDTSRPKFYACSMLPYPSGKLHMGHVRNYTINDMMARYLRMKGYNVLMPMGWDAFGLPAENAAIDKKVAPAQWTRDNIADMKSQMQPLGLAFDWSREVATCDPDYYKWNQWFFLKLLEKGIAYKKTQVVNWDPVDQTVLANEQVIDGRGWRSGAPVERREIPGYYLAITQYADELLANVADPASPGFLHGWPERVRLMQEHWIGKSAGVRFAFPHEIRDADGTLVGDGLMHVFTTRADTIMGVTFCAVAPEHPLATHAAASDPDLAAFIETCKAGGTTEAELATKDKEGRPTGLFVKHPLSGAPVPVWVGNYVLMGYGDGAVMGVPAHDERDFAFAKKYGIDILQVVHVDGEHFSYDHWQDWYADKQRGVTINSGNLSGLSYPVAVDAVAAALAAQGLGDKKTTWRLRDWGISRQRYWGTPIPIIHCTGSGPGSDNPGCGDVPVPEQDLPVLLPEDLIPDGSGNPLNKSAAFLNVACPKCGAPAKRETDTMDTFVDSSWYYMRYCCPDSDAAMVDSRNDYWMPMDQYIGGIEHAVLHLLYARFWTKAMRDCGLVKFDEPFTKLFTQGMLLNESYYREDASGKKRWFYPSEVEVQFDDKGHPVGAIAREDGQPVQLGGIEKMSKSKNNVVEPRDIIAKFGADTARLFTMFAGPPDQSAAWSDSGAEGSFRYLRRLWAFATKQREAVQAAGTDFADASRAAIDLRRDVHLLLRQVSHDYDRLQYNTVVSGAMKLLNALESAALADTAADRAALREGLGILLRALYPAAPHIAHALWQDLGYAAAHGDLLDAPWPAVDEQALVQDEIELVLQVNGKLRGALKVPASADRAAIEAAALASPELAKFAEGRTPKKVVVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_CHRSD
Sequence: MLQPKRTKFRKVQKGRNRGLAHRGSKVSFGEYGLKATGRGRITARQIEAGRRAITRHVKRGGKIWIRVFPDKPITEKPLEVRMGKGKGSVEYWVAQIQPGKVLYEIEGVSEELAREAFDLAAQKFPVSTTFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ENK7_HUMAN
Sequence: MVTPVTWMDNPIEIYVNDSVWVPGPIDDRCPAKPEEEGMMINISIGYRYPPICLGRAPGCLMPAVQNWLVEVPTVSPISRFTYHMVSGMSLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANSAVILQNNEFGTIIDWAPRGQFYHNCSGQTQSCPSAQVSPAVDSDLTESLDKHKHKKLQSFYPWEWGEKRISTPRPKIVSPVSGPEHPELWRLTVASHHIRIWSGNQTLETRDCKPFYTIDLNSSLTVPLQSCVKPPYMLVVGNIVIKPDSQTITCENCRLLSCIDSTFNWQHRILLVRAREGVWIPVSMDRPWEASPSVHILTEVLKGVLNRSKRFIFTLIAVIMGLIAVTATAAVAGVALHSSVQSVNFVNDWQKNSTRLWNSQSSIDQKLANQINDLRQTVIWMGDRLMSLEHRFQLQCDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDNLTLDISKLKEQIFEASKAHLNLVPGTEAIAGVADGLANLNPVTWVKTIGSTTIINLILILVCLFCLLLVCRCTQQLRRDSDHRERAMMTMAVLSKRKGGNVGKSKRDQIVTVSV
What is the function of this protein?
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain.  The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 7 Env polyprotein, Envelope polyprotein, HERV-K(III) envelope protein, HERV-K102 envelope protein, HERV-K_1q22 provirus ancestral Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily.
What are the subcellular locations of this protein?
Virion. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass membrane protein.
Protein: RSMJ_PSEAB
Sequence: MTDSTAPRLHVQALSADCAEAARRWAERLGLPLAADDEAEFAVQVGEEGLQVLQLGPDSPGPVRVDFVEGASAHRRKFGGGSGQMIAKAVGVQPGIRPRVLDATAGLGRDGFVLASLGCEVTLVERQPLIAALLEDGLERAGRDPDVAPIAARMRLLGGNSADLMRAWDGEAPQVVYLDPMFPHRDKSALVKKEMRLFRPLVGDDLDAPALLQAALALASHRVVVKRPRKAPIIEGPKPGYSLEGKSSRYDIYPKKALGKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIR23_ARATH
Sequence: MAKEEYVSRMLVMLIMIMPLVAQGSRLHSWANRLEETGKDKVTNLQFYFHDTLSGKNPTAVKVAQGTDTEKSPTLFGAVFMVDDALTETADPKSKLVGRAQGLYGSSCKEEVGLIMAMSFCFEDGPYKDSTISMIGKNSAMNPIREMPIVGGTGMFRMARGYAIARTNWFDPKTGDAIVGYNVTIMH
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 23, AtDIR23.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: MYG_DRONO
Sequence: MGLSDQEWQHVLTIWGKVESDLAGHGHEILMRLFHDLPETLDRFERFKGLTTPDQMKASEELKKHGVTVLTQLGKILKLKGKHEAELKPLAQTHATKHKIPVKYLEFISEVIIKVIAEKHSADFGADSQAAMKKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: XERS_STRP8
Sequence: MRRELLLEKIETYKAIMPWYVLDYYQSKLAIPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTP_SALNS
Sequence: MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATEREELKVSKITVLVLGVIAIILGILFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CASS4_MOUSE
Sequence: MRGTSIREGAPKTLLARALYDNHADCSDELAFSRGDILTIVEQNVPESEGWWRCLLHGRQGLAPANRLQVLRETPADRPCPLLPRGPDTDLTSSGAPYQVQDLISPPPQGPVYEPMRSWVEGPSPATAQVYELPESPSSARIICEKTLSFPKQALSVLPRPTRASLPTLPSQVYDVPVQRQGFSTLERLEKQQFYDIPTSSQKALLHSSTSQGRDVTLAPTMAFRQGGGYNPLSSPQKSERIHDTPVLLEKADVRNVSMTSFTKDSGSRAIPGSSAVHTGAVALSPQLGNTVQRKNSLPEEPTYAFPTSRDPLPSDAGGSYKVPSRFLIPRVEQQNTMPNIYDTPKAMQGVSHNAPKAMQGVSLAGKELERGREAPENSPWISGQTSFLSPDSDRLSVASSDSRASVVSSCSSISMDSSSGSSSEDSVKELWMDVDFAKETAVSLQHKVASSAAGLLLFVSRTWRFKDSLETNIHRIRRAADHVEESVREFLDFAQGVGGTACNLTDSYLQARIRDQLQTISSSYQTLLDAKGSLDRCNWSLEVLVTDKVQNSLDDLERFVATARIVPEDVKRFTSIVIANGKLLFKQNCEKGEMDLKCERCIRPPQRETESYQESSPFDRQPTTEHSFELARKNRVNVCWQQSPNLQEKGKPTMEGKSNRNPDFHGMSPPPLTSPSPSGQNTERKIHLSKHSRLYFGALFKAISVFASSLSNGQPPEVFITQSKLVITVGQKLVDTLCSETQEKDERNEILCGSSHLCGLLKDLALATKSAVIQYPSPSALSLLQSEVERLEHHSRKFRDTLE
What is the function of this protein?
Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading.  Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
What are the official names of this protein?
Cas scaffolding protein family member 4.
What is the protein family that this protein belongs to?
Belongs to the CAS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion.
Protein: PIP_LACAC
Sequence: MEIIEGKMPFMGYETHYRIVGRRSEKSPLVLLHGGPGSTHNYFEVLDKLAKIDDRRIIMYDQLGCGNSSIPDDHPELYTKETWVKELKTLREHLALRKIHLLGQSWGGMLAIIYMCDYHPEGIQSLILSSTLSSASLWSKELHRMIKYLPIEEQAAIHRAELTDTFTEPDYLKANEHFMNQHAIDMKKKWPECVMREKKGGTVAYETAWGPNEYTPEGNLHDYEYTDQLSKIKVPTLITSGTDDLCTPYVAKTMHDHIAGSQWKLFENCSHMSFVQKTDEYIAMLKKWLDAND
What is the function of this protein?
Releases the N-terminal proline from various substrates.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope.
Protein: ORF12_SPV1R
Sequence: MPTWLTTIFSVVIVLAIFLYFGLLIYQKIRQIRGKKKDKKEIERKESNK
What are the official names of this protein?
Uncharacterized protein ORF12, Gene 12 protein.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF12 protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: CHS1_GERHY
Sequence: MASSVDMKAIRDAQRAEGPATILAIGTATPANCVYQADYPDYYFRITKSEHMVDLKEKFKRMCDKSMIRKRYMHITEEYLKQNPNMCAYMAPSLDVRQDLVVVEVPKLGKEAAMKAIKEWGHPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDTHLDSLVGQALFGDGAAAVIVGSDPDLTTERPLFEMVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALTTAFSPLGINDWNSIFWIAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNMSSACVLFIIDEMRKKSSENGAGTTGEGLEWGVLFGFGPGLTVETVVLHSVPTTVTVAV
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: UBX_DROVI
Sequence: SGAAAAQTAAASSLHQASNHTFYPWMAIAGESTADPSKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTR
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds the consensus region 5'-TTAAT[GT][GA]-3'.  This homeotic protein controls development of the cells in the posterior thoracic and first abdominal segments.  It activates the synthesis of the decapentaplegic (DPP) growth factor (By similarity).
What are the official names of this protein?
Homeotic protein ultrabithorax.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 2ABA_HUMAN
Sequence: MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed:33108758).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, PP2A subunit B isoform B55-alpha, PP2A subunit B isoform PR55-alpha, PP2A subunit B isoform R2-alpha, PP2A subunit B isoform alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
Protein: RS11_SACD2
Sequence: MAKPSGKSTTKKKVKKTVVDGIAHIHASFNNTIVTITDRQGNTLSWATAGGSGFRGSRKSTPFAAQVAAERAGQAAQDYGLKNLDVEVKGPGPGRESAVRALNNIGYKVNNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DRE2_FUSV7
Sequence: MPVSKSVSPPKRTLLLAPPTLASHSSALSSVLADYDRSVTDLQMLDRLSAGLVKLPSSTYDRVLILADASFMLGESLALMNRAVLGPVAEALKPNGRLQSQDGNSLEESTLSKEAVLAGLVASRGGFEKPDYGDNEGAVTLKFGLKKKNQPAPLADGSVPLNFKKKKPVEVKPVVPVVPAGVGFIDLSDDLDDDDLIDEDTLMTEEDLLRPINIPVECQPKAGKRRRACKDCSCGLAERLVKEDAEKRAEADKKLESVKLATDDLAEIDFTVQGKVGSCGNCSLGDAFRCDGCPYIGLPPFKPGEEVRLLNNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: XYLA_RHILO
Sequence: MSSGFFGDIQKIKYEGPDSTNPLAYRFYNPDEVVAGKRLEDHLRFAVAYWHSFAWPGGDPFGGQTFDRPWFPKAGGIDTMELAKLKADVAFEMFSLLGAPYFCFHDADVRPEGKDFSESAARLDEIADYFAGKMKQTGVKLLWGTANLFSHRRFMSGAATNPDPDVFAYAAATVKSCIDVTKRLKGENYVLWGGREGYETLLNTDLAREQEQAGRFLSLVVDYKHKIGFKGTILIEPKPQEPTKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALANALGVFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYQILQAGGFKTGGTNFDAKLRRQSLDPQDLLIGHIGGMDACARGLKAAARMVEDKALSAPLAERYAGWNSAEGKAMLSGKRTLEDIAERVVKKKIEPQPRSGRQELLENIVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_NEIMB
Sequence: MNIEVEMKVLDERMADVVPVYATEGSAGLDLRACLDEEVVLQPGETFLVPTGLAIYLANPAYAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGELKVSLWNRSSEPFTVKPFERIAQMVVVPIVQAGFKRVEEFVGSSRGEGGFGSTGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.