PharMolix/UniProtQA huggingface dataset:
Protein: RS18_PROM0
Sequence: MPNSIFKKQLSPIKPGDPIDYKDVELLKKFITERGKILPRRMTGLTSKQQRDLTLAVKRARIVALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AB8C_ARATH
Sequence: MAAFIGSLPWCDVELNLASSCFQRTAIAFVNLLFLCIFYLFLIASCVSTHFIVRGRKKGWIFVAVAICCAITSFIFLGVGLNSLIHGGNDVTEISWVACFVEGIIWVSLAVSLLVNGSKWVNILVSVWWVSFALLDLVAKSGILLQGNGIRILDILTLPMSLLLLLCSWMNLRSSSAAAQDCSVTGLSDPLLTKNPRKESARLATAGFFSILSFSWMNPLLSLGFKKPLSPEDIPSVVPEDEAQLAYKKFSQAWDTLLGDESSTKERNLVFRAVVKVYFKENIFIAVFAFLRTFAVVSLPLMLYVFVDYANSDHRDLRNGFFNLACLVMLKLVESLTMRHWYFASRRSGMRIRSALMVAAYKKQLKLSSLGRKRHSSGEIVNYIAVDAYRMGEFLWWFHSGWSLSLQLLLSTAVLFGVVGAGAFPGLILLLLCGLLNLPFAKMLQNCQTQFMIAQDKRLRSTSEILNSMKVIKLQSWEDEFKKKIESCRDDEFTWLAKAQLTKAFGSFLYWMSPTIVSSVVFLGCALLKSAPLNASTIFTVLATLRVMSEPVKIIPDAISAIIQGNVSFQRLNNFLLDDELKMDEIERSGLDASGTAVDIQVGNFGWEPETKIPTLRNIHLEIKHGQKVAVCGPVGAGKSSLLHAVLGEIPKVSGTVKVFGSIAYVSQTSWIQSGTIRDNILYGKPMESRRYNAAIKACALDKDMNGFGHGDLTEIGQRGINLSGGQKQRIQLARAVYADADVYLLDDPFSAVDAHTAGVLFHKCVEDSLKEKTVILVTHQVEFLSEVDQILVMEEGTITQSGKYEELLMMGTAFQQLVNAHNDAVTVLPLASNESLGDLRKEGKDREIRNMTVVEKIEEEIEKTDIPGVQLTQEEEKESGYVGMKPFLDYIGVSRGWCLLWSSVLGQVGFVVFQAASTYWLAFAIGIPKITNTMLIGVYSIISTLSAGFVYARAITTAHLGLKASKAFFSGFTNAVFKAPMLFFDSTPVGRILTRASSDLNVLDYDVPFAFIFVVAPAVELTAALLIMTYVTWQVIIIALLALAATKVVQDYYLASARELIRINGTTKAPVMNYAAETSLGVVTIRAFGTAERFFKNYLNLVDADAVLFFLSNAAMEWVILRIETLQNVTLFTCALLLILIPKGYIAPGLVGLSLSYALTLTQTQVFLTRWYCTLSNSIISVERIKQYMNIPEEPPAIIDDKRPPSSWPSNGTIHLQELKIRYRPNAPLVLKGISCTFREGTRVGVVGRTGSGKSTLISALFRLVEPASGCILIDGIDISKIGLKDLRMKLSIIPQEPTLFRGCIRTNLDPLGVYSDDEIWKALEKCQLKTTISNLPNKLDSSVSDEGENWSVGQRQLFCLGRVLLKRNKILVLDEATASIDSATDAIIQRIIREEFADCTVITVAHRVPTVIDSDMVMVLSFGDLVEYNEPSKLMETDSYFSKLVAEYWASCRGNSSQNLQL
What is the function of this protein?
Pump for glutathione S-conjugates.
What are the official names of this protein?
ABC transporter C family member 8, ABC transporter ABCC.8, AtABCC8, ATP-energized glutathione S-conjugate pump 6, Glutathione S-conjugate-transporting ATPase 6, Multidrug resistance-associated protein 6.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AIM24_AJEDR
Sequence: MEAMSHSIRRSLQPFARSRRSWRSPARRAEQRWIHIQQLQSAEPGLVNGNYLPASTTANSASSPDAKFQVLGAPYSLLSVTLSASQNLYTRRGTLVGLSGKADNVISTLSLLEPARRALLRIPFLYQKISSTSPITALISTRSAITTFSVVEMNGSVDWMIAQEKALLAWTGHSLRIKPRLTRQLSLSHWGNSEVTGRGLLALVGTGQLYSVELKAGEQYISHPSNVVAYTITAPSPRPYRFKSTILPFQIPSLGIGKRLSDSNFIKNLSDTDTWKAALKLWHIIRTWSRRTIWGDRLFLQFDGPATILVQSRASRMADTLTTQQVNEIADAPPGVTQDAVDRAAAKLGEEETVPKAKDDLKPTTAISGQSVASVRRDGKVEFHQTGVGQ
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YCIU_ECO27
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: DUSKY_IPONI
Sequence: MGSQATTYHMAMYPWFGVGHLTGFFRLANKLAGKGHRISFLIPKNTQSKLESFNLHPHLISFVPIVVPSIPGLPPGAETTSDVPFPSTHLLMEAMDKTQNDIEIILKDLKVDVVFYDFTHWLPSLARKIGIKSVFYSTISPLMHGYALSPERRVVGKQLTEADMMKAPASFPDPSIKLHAHEARGFTARTVMKFGGDITFFDRIFTAVSESDGLAYSTCREIEGQFCDYIETQFQKPVLLAGPALPVPSKSTMEQKWSDWLGKFKEGSVIYCAFGSECTLRKDKFQELLWGLELTGMPFFAALKPPFEAESIEAAIPEELKEKIQGRGIVHGEWVQQQLFLQHPSVGCFVSHCGWASLSEALVNDCQIVLLPQVGDQIINARIMSVSLKVGVEVEKGEEDGVFSRESVCKAVKAVMDEKSEIGREVRGNHDKLRGFLLNADLDSKYMDSFNQKLQDLLG
What is the function of this protein?
Glycosyltransferase that mediates the glucosylation of anthocyanidin 3-O-glucosides to yield anthocyanidin 3-O-sophorosides.  3-O-sophoroside derivatives are required for the bright blue or red color of flowers.
What are the official names of this protein?
Anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase, 3-O-glucoside-2''-O-glucosyltransferase, In3GGT, Protein dusky, Dy.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MTNB_VANPO
Sequence: MTERSFDSFEVVENGLTEEQILQNPDCLISSHDENHPANVICKLCEQFFHNNWCTGTGGGISIKDPKTNYLYIAPSGVQKEKMKREDLFVLNETGDKCLRKPSMYKPSACTPLFLACYKLRNAGAIIHTHSQHAVMCSLIFKDVFRISNIEQIKAIPSGKIDPVTNKQIALSFFDTLEIPIIENMAHEDQLIDSFHDIFKRWPHTQAIIVRRHGIFVWGSDINKAKIYNEAIDYLMELAVKMYQIGIPPDCGIGEEKRYLEMPM
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCCP_CHLTR
Sequence: MDLKQIEKLMIAMGRNKMKRIVIKREGLELELERDTVPSIQEPVFYDNRLFAGFSQERPIPTDQNLGNPIVKESIEKKESEAPAQGDFIVSPLVGTFYGSPSPEAPAFIKPGDTVSEDTVVCIVEAMKVMNEVKAGMSGRVEEILITNGDPVQFGSKLFRIVKA
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.
Protein: HFQ_SHISS
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RNH2B_YEAST
Sequence: MTVSNIGGEERLIILPDDYETSKTINTFTLPPPSNITSKPRIELFENINGKLYEIRSFQFGKGPSYSHEEDLANDKYHYTKENHPIKSTFIVNTSDPTDGYVFNSSKIHFCSLYDIAFSLIGFYYRNSVSADEQDYSNSSDTGENQKSNSKTNEKFLTVRDYHDFLTDNHDKNWENISLSRLKSGLAKVSETIEEAGDVYYKITSAMITQFLLGKVSKIVENFPPSIPTLKNAPTEIKQCYKVVMATNLLVSLIPRAAYHNLLTFSPTMDSGCLNPDIKASFIELENYETTNELQNAERELLMKSAMNVGLNSNGRVSLPVKKVTKKIVQNKKPKVAIGKGAIDGFFKRK
What is the function of this protein?
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
What are the official names of this protein?
Ribonuclease H2 subunit B, RNase H2 subunit B, Rnh2B, RNase H(202), Ribonuclease HI subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNase H2 subunit B family. Highly divergent.
Protein: MTDC_DROME
Sequence: MRFTSNMAQIIDGKAIAQEVRTQLAHELKGMEAAGYPKPHLTAVIVGEDPASEKYVANKMVACREVGISSETKRLPASTTQEELLQLIADLNKDPQVTGILVQLPVPEHINERTICNAVDVDKDVDGFNEVNIGRTALDMEANIPATPLGVKRLLEHMKIETLGRNAVVVGRSKNVSLPMAILLHADGKYATKAMDATVTICHRYTPPKELARHCRQADIIVVAVGKPGLITKDMVKPGACVIDVGINRIKDESTGQFKLVGDVDFEEVRQVAGHITPVPGGVGPMTVAMLMHNTLKAARKQFDDRKSS
What is the function of this protein?
May play a role in spermatogenesis.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, DNMDMC.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BETB_ACIAD
Sequence: MSDVKLHRLYIHGQYTDATSGKTFDSINPATGEVIATIQQASQTDIEAAVKSAAEGQKVWAAKTAVERSRILRRAVDILRERNDELAQLETLDTGKAFSETSTVDIVTGADVLEYYAGLATAIQGEQVPLRESSFFYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTAFKLAEIYSEAGLPAGVFNVVQGAGREIGQWLTEHAVIEKISFTGGVETGKKVMASAAGSTLKEVTMELGGKSPLIICEDANLDRAADIAVMANFFSSGQVCTNGTRVFIPQRLKAAFEQAVVERVKRIRMGDPQHTDTNFGPLVSFPHMEKVLSYIESGKQQGAKVLIGGERATTGLLAQGAYVQPTVFTDCHDDMKIVQEEIFGPVMSILTYDTIEEAIERANNTNFGLAAGVVTQNISQAHQIIHQLEAGICWINTWGESPAEMPVGGYKESGVGRENGISTLNHYTRTKSIQVELGDYQSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: YBEY_ECO45
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_HAEIN
Sequence: MPFWYSNSKLIWLLSPFSLLFWLISQLRRALFSLGLKSSYRAPKPVIIVGNLSVGGNGKTPVVVWLMEELKKRGLRVGVISRGYGSKSKTYPLFVTKNTNPIEGGDEPVLIAKRTNAPVVISPNRQQAIELLLSQAECDIIISDDGLQHYQLQRDLEIVVMDAERALGNGFVLPAGPLRELPSRLKSVDFVITNGGKNQYSDAVMRLVPHFAINLKTNEKRQLNEFQSGVAIAGIGNPQRFFTMLEKLGIQLKQTQAFQDHQHFEASQLEKLAENQPLFMTEKDAVKCQSFAKDNWWYVPVDAEIIEAEKQRENLPHFWAKIDKLVEQYRNG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RAP1_PHYPO
Sequence: MPLREFKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSIIAMSTFNDLPDLREQILRVKDCDDVPMVLVGNKCDLAEQRVISTEQGDELARKFGGCAFLEASAKNKINVEQIFYDLIRQINRKNPGPTNKKEKKSGGCILL
What are the official names of this protein?
Ras-related protein Rap-1, Pprap1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LPRE_MYCTO
Sequence: MPGVWSPPCPTTPRVGVVAALVAATLTGCGSGDSTVAKTPEATPSLSTAHPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDPRSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQGVPDTYGFTGIDTSQCTGDTVALTYASGIGLNNVVKFRWNGGGVELIGNTTGG
What are the official names of this protein?
Putative lipoprotein LprE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PRTY2_CLUHA
Sequence: PRRRTRRASRPVRRRRPRRVSRRRRARRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-YII, Clupeine-YII.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PSBE_CYAPA
Sequence: MSGGTTGERPFSDIVTSIRYWVIHTVTIPSLFVAGWLFVSTGLAYDVFGTPRPDEYFTEERQEVPIINQRFSTN
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: NU2C1_ORYSA
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFQGSFIFPECILIFGLILLLMIDLTSDQKDRPWFYFISSTSLVISITALLFRWREEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKRDLRSNEATMKYLLMGGASSSILVYGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGLGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAALALATRILDIPFYFSSNEWHLLLEILAILSMILGNLLAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIVKLLMTGRNQEITPYVRNYRRSPLRSNNSIELSMTVCVIASTILGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YNC9_CAEEL
Sequence: MWPSNRGPTLFQYSIRCLGFVAFIGVVRCHCPHMMGVKPPGPPSGPSPPGKFPDGDEGWDYDETAAPGIVPEPHFIQSTYIYRSPNVQEKTFSSRVVNVLKDIRTRLAKSARLTLENENIECSSPTDHYRCQEYPASGTWNYLIVEDQQKGAVTYTFDRKFNEKNDGTIEMALLDAFSRHSPSSLIAFASSEAEKEVGYIRALTVQEMDSLSGKRSHQKISMEKFGPNELILLEPALLEVRTGANLKLNSDSLRRIDSTKEFDKLLEEFRNVFILFWNSNRMVSLHTFNLWSRVADKIKISEDTLLAHVPCHDNADFCQGLNSEDYHTVVSYRNGQNTGKTENIGDVEFYENWVELSLSGAIQRLPNESKLSEFKKGIVGGKKRSSVTIGVFPSDQDTSFQHFQIAAEKLSGKYYVAYFINENSKPAITTYRHAEKQKRTDYSGKFDPATLMEFITKSSIPSIIGISNGFTTDLLFHQKRPILIQIGGAGEFEPFSKLSARQDARKTYIFTKIDGESEMIKKTKKALGVGENESIIVFLNKDRVHRIPISKPKCPDHLQKILQMIITSEADQVLSTKEPHPLRYLQVEKVNEVFGFEETLVLPDHTLFLDSDPFSRHPPITEGGGGGCPFMQGGGAPTESSQHSEL
What are the official names of this protein?
Uncharacterized protein R05D3.9.
Protein: HSLO_YERP3
Sequence: MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_VIBCH
Sequence: MLKTTIIGASGYTGAELALMVHKHPQLTLSGLYVSANSVDAGKSLAQLHGRVAGLIDMPVQALTDVDTVAAECDVVFLATAHEVSHDLAPQFLAQGCQVFDLSGAFRVQSEAFYPTFYGFAHQHSEWLEKAVYGLAEWNAEAIKTSPMIAVAGCYPTASQLAIKPLLVDGLIDTTQWPVINAVSGVSGAGRKATMTNSFCEVSLQPYGVFNHRHQPEIATHLGCEVIFTPHLGNFKRGILATITMKLADGVTEQQVAEAFSKAYQDKPLVRFSNGLPRIQDVEFTPFCDLGWKVQGRHIIVVSAIDNLLKGASSQAMQCLNIHYGFDELTALV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAPAT_CERS1
Sequence: MAFLSDTLARVKPSQTIAVTNKARELAAAGRDVIGLGAGEPDFDTPDNIKAAAKRAIDAGRTKYTAVDGIPELKRAICEKFERENGLKYTPAQVTVGTGGKQILYNALVATLNPGDEVIIPAPYWVSYPDMVLLAGGTPVSVAAGMETGFKLTPEQLEAAITPRTKWFIFNSPSNPTGAAYTRAELAALCEVLMRHPQVWIMSDDMYEHLVFDDFDFTTPAQIEPGLYDRTLTCNGVSKAYCMTGWRIGYAAGPVELIRAMGTIQSQSTSNPCSIAQYAALEALSGPQEFLATNREAFQRRRDLVVSMLNEAKGVTCPNPEGAFYVYPDISGCIGKTSAGGAKITDDEAFASALLEETGVAVVFGAAFGLSPNFRISYATADEVLREACARIQAFCAGLS
What is the function of this protein?
Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate (PubMed:24302739).  Can also transaminate prephenate in the presence of glutamate (PubMed:24302739).
What are the official names of this protein?
Aspartate/prephenate aminotransferase, AspAT / PAT.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQY1_CAEEL
Sequence: MDSETDTDTHSICNSVSSGENYKSPESSDCEGYATPLASSLTDISNVINHSVTIKVPDTIADANDLEPGERTPVSTPRAISPPIVKQVMYLQKPRILVMTQREIHEECCSSEEEFYDVDDVQIRDVAQQLLNGVSDDKTETEAGNNDVIIAEEDRADTPIVIEDTREFEETYSEEDERQTPIQMENATSEVSSSEDEISDSVVELTNDMMSKITEIEEIHAQVHSESFGSSDSGDHLEVKSEATNFPEYSNTEEFEVPKNDYVTVENVNESTIDSVVIDSQTPTKDTKNEVNISQNVVNLVRLESHLENYDDETTNTVIAECVYDAQENEKCEKNEEDDLSPVLDSNKIKNSPESKFCEFRAESECYEQTEETDQIKQFVPLMEVSVANQEFDELCDIERNGGNSKDRPKDLNENVKAFDAEHHENSVLEYEQLPDVFSEITIAKTPIPVVHENSISGVSKESQVSFNQEAVQNELMPTHIISDEVETSSTTADNNIPFSDCSTHKVKVDFDGYSSGKEESLSSSTSSESFEFAEPVTENHIQDERAQALRNSIIERYPSNDTDDDELDSVGDEFDEDLLAVKQISAEVEQLVAAINAFGRDEEQQMSAYMVGKKMAAEKKRKSAMDTTAMTSSCQDQTVQTDNNSFILVDRHVPEVMESLQVEIDRLQGDLEKVKSGEKELLQINSKLKEELEESQQTIDGIEIEAEQQYTELTSEIDELCEIVQRKDQELAILKEKVTNVINIENSLKDDVDSQKVIVQRQKEIIENLREELDAITKKLGEVTKLRDKAVEEATLYKMKNMERDRFLSREAQMSMEIEDLQRELNKQKLILNQTSMAKLADTFDRKVLHLENELRERDMLICKQNQIINSHRKSPTGSVITHRKMQPRASVLAAAGNLPSAGSSSESFQNGLDVEAREALLSFILSDRHNQLANIYNIGRILDLTPQEERSVERHLTKDRFT
What are the official names of this protein?
Uncharacterized protein F36G3.1.
Protein: DPO3B_STAAW
Sequence: MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVILTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQFQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETRPVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDNEEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAIDRASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYMMDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_HAEIE
Sequence: MDSRRSLLVLALIFISFLVYQQWQLDKNPPVQTEQTTSITATSDVPASSPSNSQAIADSQTRGRIITLENDVFRLKIDTLGGDVISSELLKYDAELDSKTPFELLKDTKEHIYIAQSGLIGKNGIDTRSGRAQYQIEGDNFKLAEGQESLSVPLLFEKDGVTYQKIFVLKRGSYDLGVDYKIDNQSGQAIEVEPYGQLKHSIVESSGNVAMPTYTGGAYSSSETNYKKYSFADMQDNNLSIDTKAGWVAVLQHYFVSAWIPNQDVNNQLYTITDSKNNVASIGYRGPVVTIPAGSQETITSSLWTGPKLQNQMATVANNLDLTVDYGWAWFIAKPLFWLLTFIQGIVSNWGLAIICVTIVVKAILYPLTKAQYTSMAKMRILQPKMQEMRERFGDDRQRMSQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGISMFLLQKMSPTPVTDPTQQKVMNFMPLIFMVFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURD_PROM5
Sequence: MPIKNNSKNEKKIYFVIGLGRSGFWAAKYLRSLGKKVIVWESNENEELSETKEILEKLDISVCLNKQFLFEEFSECLNQIEAVVISPAIPIDHKTIIKLKEKGIEVLGEVNIAWESLKNINWIGITGTNGKTTVTHLLSHILRTNNLLAPFAGNIGTPLCKIAYSIKSKNIDWLVAELSSYQIEIATLCIKPKIGIWTTFTADHLDRHKTLDNYFKIKNSLLKQSEFRIYNYDDIHLRENFKSLSKGIWITTSSKQSDLDHCDYWINNEDFIVERQENLLSLKNFKLKGNHNTQNLLLAIAAARKIGLSPEKIKNALLSYEQLPHRMETIYQSNKLEIINDSKATNFDSSTAGIKAIKGAPIIISGGKLKSGSYIEWVNIINKKAKAVFLFGESSQTLKKLILEGGFKKDIFIFNDLSEVINYVYSYIENNQIETLLFSPSCSSFDQFRNYEERGDIFKKLIHEKFNLKLFAHKEFS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAT2_MOUSE
Sequence: MDTKYKDDLFRKYVQFHEGKVDTTPGNQQPGSDEYLRVAAATLLSLHKVDPLYRFRLIQFYEVVESSLRSLSSSSLSALHCAFSMLETMAINLFLFPWKKEFRSIKTYTGPFVYYVKSTLLEKDIRAILRFMGYEPELGTVYKLKELVESLQVKMVSFELFLAKVECEQMLGIHSQVKDKGYSELDVVAERKGSTEDARGCSDALRRRAESREHLTTSMARVALQKSASERAAKDYYKPRVTKPSRSVDAYDSYWESRKPPSKASLSLRKEPLAMDVGEDLKDEIIRPSPSLLAMSSSPHGSPDDLSSISSINGLGLLRSTYFSTQDDVDLYTDSEPRATYRRQDALRPDVWLVKNDTHPIYHKRSPPTKESALSKCQNCGLSCSSSLCQRCDSVLVCPSASKPSAFPSKASVHDSLAHGAPMREKYVGHQTQGLDRLAPVHSKPKPSTTATSRCGFCNRAGATNTCTQCSKVSCDACLGAYHYDPCCRKSELHKFLPNSQLNYKSAPFSQLVYR
What is the function of this protein?
Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis (By similarity).  Acts as a direct binding intermediate that bridges RNF31/HOIP, the catalytic subunit of the LUBAC complex, and the deubiquitinase (CYLD), thereby recruiting CYLD to the TNF-R1 signaling complex (TNF-RSC) (By similarity).  Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of CYLD (PubMed:28701375).  Controls the kinase activity of RIPK1 and TNF-alpha-induced necroptosis by promoting 'Met-1'-linked deubiquitination of RIPK1 by CYLD (PubMed:28701375).
What are the official names of this protein?
Spermatogenesis-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the SPATA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.