PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_PASMU
Sequence: MTSSLPNIGFISLGCPKNLVDSERILTELRSDGYNIIPSYENADLVIVNTCGFIDSAVQESLEAIGEALEENGKVIVTGCLGAKEDRIREVHPKVLEVTGPHSYEAVMQQVHKYVPKPAYNPYVNLVPKQGVKLTPKHYAYLKISEGCDHRCTFCIIPSMRGDLDSRSITQVLDEAKRLVEAGVKEILVVSQDTSAYALDRSKEEQNKTVFWNGMPIKNNLISLCEQLGKLGVWVRLHYVYPYPHVDQLIPLMAEGKILPYLDIPLQHASPKILKAMKRPGSIERTLERIKKWREICPDLTLRSTFIVGFPGESEEDFQLLLDFLKEALLDRVGCFKFSPVEGAIATEMPDQVPEEVKEARFHRFMQLQQEISAARLQQKVGKVFTVLVDEVDEEGIIARSIADAPEIDGVVYIDNPNRVAVKAGQFIEVKITRADAYDLYASLIN
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y942_MYCTU
Sequence: MGRSATIAMVPKRRDAMNRHSGPILSSGFIASSSNSCPANSLRMPSALAAETLSFDDRAVRRSTHHPGGGYPQKHAINLQSGLCPAYANASR
What are the official names of this protein?
Uncharacterized protein Rv0942.
Protein: Y3615_XANOR
Sequence: MSRVKKLHQWKERLRDRARTVSFGRFLWRRFLDDRLFQAAASLAYTTVFALVPLAIVVFGVLSAFPAFNEWKDALTDFIFTNFVPGAARSVQNYLNRSLEDLGKFTVAGMVALVASLLITLHSIEQTFNSIWRVAAARPKVTRFLIYWTVLTLGTMLAAASMAMAAYVFALPLFRTTEGQWLAEFAWRLAPMAVEFICIVLIYRVVPQHVVRLRHALPGALLAVILMEIVKWGFGVYLGNFQTYQRIYGALSALPILLLWIYLSWVSVLLGASLASSMAAFRYQPEAMRLPTGFEIYGLLRLLGRFRQARIHGEGLDEDRILALEPMLTDTLMQELLCELKRMRLLRRDERGQWLLARDLDLVPLAELYENCQLRVPIEDRPLPCRDDAYGQAAAAALEQLRQPLRSVLAQPVGDLYTHLPGDPP
What are the official names of this protein?
UPF0761 membrane protein XOO3615.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WHB5A_MYCTU
Sequence: MAHPCATDPELWFGYPDDDGSDGAAKARAYERSATQARIQCLRRCPLLQQRRCAQHAVEHRVEYGVWAGIKLPGGQYRKREQLAAAHDVLRRIAGGEINSRQLPDNAALLARNEGLEVTPVPGVVVHLPIAQVGPQPAA
What is the function of this protein?
A transcription factor that is probably redox-responsive.  Probably plays a role in immunomodulation and reactivation after chronic infection.  Its induction results in transcription of a number of genes including sigM, and the genes for 2 type VII secretion systems ESX-2 and ESX-4.  Seems to negatively regulate its own expression.  The apo-form has been shown to act as a protein disulfide reductase.  The apo- but not holo-form probably binds DNA.
What are the official names of this protein?
Transcriptional regulator WhiB5.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_SYNR3
Sequence: MDRNPNPNNLPVELNRTSLYLGLLLVFVTGVLFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: NAR4_MOUSE
Sequence: MALWLPGGQLTLLLLLWVQQTPAGSTEAPLKVDVDLTPDSFDDQYQGCSEQMVEELNQGDYFIKEVDTHKYYSRAWQKAHLTWLNQAKALPESMTPVHAVAIVVFTLNLNVSSDLAKAMARAAGSPGQYSQSFHFKYLHYYLTSAIQLLRKDSSTKNGSLCYKVYHGMKDVSIGANVGSTIRFGQFLSASLLKEETRVSGNQTLFTIFTCLGASVQDFSLRKEVLIPPYELFEVVSKSGSPKGDLINLRSAGNMSTYNCQLLKACSKKCAPAPVVIGCLFLVTVVISSKSRAQRNLLAPF
What are the official names of this protein?
Ecto-ADP-ribosyltransferase 4, ADP-ribosyltransferase C2 and C3 toxin-like 4, ARTC4, Mono(ADP-ribosyl)transferase 4, NAD(P)(+)--arginine ADP-ribosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane; Lipid- anchor, GPI-anchor.
Protein: FABG1_BRANA
Sequence: MATTVAATKLTSLKAVKKLGFREIRQVRQWSPLQSAMPHFGMLRCGSRQSFATSTVVKAQATAVEQSTGEAVPKVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAYGGQAITFGGDVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRYGQPEDVAGLVEFLALSPAASYITGQAFTIDGGIAI
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic, 3-ketoacyl-acyl carrier protein reductase 1, Beta-keto acyl-carrier protein reductase 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=And non- photosynthetic plastids.
Protein: AHPC_STAAW
Sequence: MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_DESHD
Sequence: MAKKVVGLVKLAINAGKANPAPPVGPALGQHGVNIMAFCKEYNERTKDQAGLIIPVEITVYEDRSFTFITKTPPASILLKKAANINSGSSEPNRKKVAQVSKTKVREIAETKMKDLNAASVEAAMSMVEGTARSMGITIVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CHS3_USTMA
Sequence: MAYYSRPASAGAARAQDDQDPYPYYPDPDLIVGSGANTSFVNPYEASGAASSASHTSPFSDAHAASASPASILPLSHQQVSAHAPQQQHMSISVDPRDGQQSRMPGLSESFYSQAAYALASPPPAAGALSPSAHLATLPEHSQAPLSGSVDGEYTYYSQSAAGHYSSLAHRHGQDDEDDDDAETKYSPSSAHDEKYAYDRPDSAAAGTSPFGRAAGIAYLQSPYAQVARNDDDDEDEDAEDPYRVLTRDSAFGGDNGQGYDPNSAYGGAGMAGPTGQFGDNHFDTQHFGPAPARGAQLRRHKTKKNVRLTKGNLILDCPVPTKLQTFLTRRAEDEFTTMRYSAVTCDPDDFASESFTLRPALYGRHTELFIAITMYNEDEVLFCRTFHGVMKNIAHLCSRNKSRTWGKDGWKKVVVAIISDGRKKIHPRVLDCLAALGVYQDGVAKNMVDGKEVRAHLYEYTTQLSIDSNLQFKGAERGLVPMQIIFCLKEKNAKKINSHRWFFNAFCPILQPNVTILLDVGTRPENKSIYYLWKSFDLNSNVAGACGEICAETKGKWGVGPLLLNPLVAAQNFEYKISNILDKTTESVMGYISVLPGAFSAYRYIALQNDEFGHGPLASYFKGENLLGADADVFTSNMYLAEDRILCFELAAKRGHGWVLKYVKSARGVTDVPEGLPEFISQRRRWLNGSFFAAVYALYHTAQFVRSGHNVWRKSLLVFESFYSFVNMCFAWFGLANYYIFFRILTTSLEDPTFKLRGIGVFNVFMQYIYLGTVVSSFIFAMGNRPQGSKWKYWAAVVVFALLTVYMMVAAVLCLSKVVARVEHDAIYAQMVVSLLATYGVYLISSLLACDPLHLITSFLQYLLLAPTYINILNIYAFCNLHDFSWGTKGDTSISADLGAVVSTSKGTVEITLPTAQADIDTAYDDALNNLRTRPMIIRGDASNAEKEARQMDYYKNIRTNVVLAWALSNGVLAAFILNGDAAGTFSDTGGVTRTKVYMVLVLIFVAGMACIRFIGSTLYLTIRLING
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 3, Chitin synthase I, Chitin-UDP acetyl-glucosaminyl transferase 3.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=A constitutive cytoplasmic pool is present that localizes to intracellular microvesicles termed chitosomes. Chitosomes constitute a separate secretory route distinct from the typical secretory pathway and serve as a vehicle for delivering the enzyme to the sites on the cell surface where polysaccharide sythesis takes place. Localizes to septa of yeast-like cells and to the basal septum separating the living tip cell from the vacuolated part in hyphae.
Protein: RS21_ECOL5
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PESC_MOUSE
Sequence: MGGLEKKKYERGSATNYITRNKARKKLQLSLPDFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIKFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNAVERLKDNKPCYKLDHIVKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFLHYVITARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEGQAQAETKISEDTYALDSESSMEKLAALSASLARVVVPAIEEAEADEFPTDGEVTAQEEDRKKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDVTDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGMQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGHLEEEEEEDEDDDNEGDVAAENEEEDVEVESEEEEEEEVHLSALEQHRLEEKKPQVMAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDDAVRSEKKAKRTRPV
What is the function of this protein?
Component of the PeBoW complex, which is required for maturation of 28S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
Protein: LIPA_BRUC2
Sequence: MVTVLNTVNQSGRLRHPEKAHRPDNEVLKKPDWIRVKAPVSRGYGETREIVRSNKLVTVCEEAGCPNIGECWEKKHATFMIMGEICTRACAFCNISTGIPNALDPNEPENIAKAVKQMGLTHVVITSVDRDDLADGGAHHFAEVIKAVREAAPATTIEILTPDFLRKEGALEIVVKARPDVFNHNLETVPSKYLKVRPGARYFHSIRLLQRVKELDPTIFTKSGIMVGLGEERNEILQLMDDLRSADVDFMTIGQYLQPTRKHHPVIRFVKPDEFKSFETIGKTKGFLLVASSPLTRSSHHAGEDFAKLKAAREALYASRAS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAC1_TACGI
Sequence: KWCFRVCYRGICYRRCR
What is the function of this protein?
Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.
What are the official names of this protein?
Tachyplesin-1, Tachyplesin I.
What is the protein family that this protein belongs to?
Belongs to the tachyplesin/polyphemusin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOD_RALSO
Sequence: MPVRFDCFVTGTDTEIGKTLASAALLTALAGAGYRTAGLKPVAAGTLAGAPERTNEDIEQLRAAATVGLPMATLCPWLLDAPMSPHLAARRAGVTITLPPIVDALAQARTQADAVVVEGVGGFRVPLSDTFDTAQLAVALGLPVVLVVGLRLGCLNHAALTAEAIAARGLRLAGWIGNVVDATMAGLDDNVATLRRWIDAPHLGTIPRLPRPDARLAASHVDIAPLLAR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y250_AQUAE
Sequence: MNKELLEKCKQKLLEEKAKILERYLEKEETQQRLGEESKEPRDWEDIGQMTYTEELLDNLSNVEIATLREIDYALEKIEKGTYGICERCGEEIPEPRLCAIPWTRYCAKCAEEVERESGTYMPSYGVDMYNPENIQVEREDIGEA
What are the official names of this protein?
Uncharacterized protein aq_250.
Protein: QUEF_CUPNH
Sequence: MSLPEHSPLGKPSAYKTEYDASLLFPIPRQPKRTEIGLPEGKPVPFFGVDIWNAYELSWLNLKGKPQVALASFIIPSDTPNIIESKSFKLYLNSFNQTRIASPEALQQLLHHDLSEATGGTVQVRLVTEADLGKQKMGELDGLLLDRLDIEVDRYEPAPELLSADQQESPVEETLVSHLLKSNCLVTGQPDWGSVQIRYVGAPINQEGLLKYLISFRNHNEFHEQCVERIFMDVMRECKPVKLAVYARYTRRGGLDINPFRTNFNTAWPDNKRNARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD1_VIBCH
Sequence: MATPHINAQMGDFADVVLMPGDPLRAKYIAENFLDNAVQVCDVRNMFGYTGTYKGRKISVMGHGMGIPSCSIYVTELIKDYGVKKIIRVGSCGAVNEGIKVRDVVIGMGACTDSKVNRIRFKDHDFAAIADYKMVKAAEEAAKARGIDVKVGNLFSAELFYTPDPSMFDVMDKYGIVGVEMEAAGIYGVAAEYGAKALAICTVSDHIKTGEQTTSEERQNTFNEMIEIALDSVLIGDQAGY
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 1, PNP 1.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ARGC_PSEA6
Sequence: MIKTCIVGASGYTGAELASLIHRHPRFELNALYVSAKSQDADKKLGDVHGYLFGQINLPLIPLTDDVLHSLSNEMDVIFLATPHEASHDWMPVLSSGKAKVFDLSGAFRLKDQQVFADYYGFAHEQAASLKQAVYGLADWFAEDIKSADIIAVPGCYPTASLSALKPLHEAGLIADGHLPIINAVSGVSGAGRKAAMGSSFCEVSLQAYGVLGHRHQPEISAYLGREVIFTPHLGNFKRGILATITVKVNADVDAGAVANAFSHAYQNHPIVRIRDTWPKLDDVVGTPHCDLFWKLDTQKGYLVVTSAIDNLLKGAASQAVQCANLRFGFASQLGLVHEVSA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_VIBVY
Sequence: MFCIQCEQTIQTPAVKGCSFAQGMCGKTAEVSDLQDVLVYSLQGVSYWATQAHRYGIINDEINQWAPKAFFSTLTNVNFDPERILQLTSQAAQFKAQLKDQVLTASSLANSPLSEVPAVAEFELPENAQAILAFAPQVAVNRGKESVHEDVIGLRLLCLYGLKGAAAYMEHARVLEQTSNDIYAEYHEIMAWLGTDPEDLGELLDCSMRIGLMNYKVMEMLDHGETATFGHPVPTAVNVKPVKGKCILVSGHDLHDLEKILQQTEGKGINVYTNGEMLPAHGYPELNKYPHLVGNYGSAWQNQQKEFANFPGAIVMTSNCLLNPNVGQYADRLFTRSIVGWPGVAHIEGDDFSAVIESALAQPGFQHDEIEHMITVGFGRNALMNAAPAVIDQVKQGNIKHFFLVGGCDGDKAERSYYTDFTEAAPEDTLILTLACGKFRFNKNTFGDINGIPRLLDVGQCNDAYSAIQLALALAQEFDCGINELPLTLVLSWFEQKAIVILLTLFALGVKGIYTGPTAPAFLTPNLIAIIQEKFDMRSIGNVQDDLNTILAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_NATPD
Sequence: MRDPDALLVRAGVRGDPERDQHFLIDDRVLDRLPGYLPDSADTDHVLEIGGGTGALTDRLLDVADRVTVIERDPGLATFLTDEFADEIEAGSLTVIEGDALEVPLPDFTASVSNLPYGVSSEIAFRLLPEKRPLVLMFQQEFAERMAAEPGTDEYGRLSVTAGHYADVEVVEPVPKEAFSPPPAVESAVVRTTPREPPYEVPDDELFMRLVRAVFTQRRKTMRNAVRNTTHISGIEDAEAVVEAAGEDLMSKRAGNVPPEAFARLAAIAAEVDG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOM7_PIG
Sequence: MVKLSKEAKQRLQQLFKGGQFAIRWGFIPLVIYLGFKRGADPGMPEPTVLSLLWG
What is the function of this protein?
Required for assembly and stability of the TOM complex (By similarity).  Positive regulator of PRKN translocation to damaged mitochondria.  Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM7 homolog, Translocase of outer membrane 7 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom7 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: NUSG_HALH5
Sequence: MEKNWYVVHTYSGYENKVKTNLEKRVESMDMTDKIFRVMVPVEEETEVKNGKSKQVSRKVFPGYVLVEMVMTDDSWYVVRNTPGVTGFVGSAGAGSKPTPLLPEEVDAILRQMGMQEERQVEIDFQLKESVKVKEGPFANFIGTIEEIQLDKRKLKVHVNMFGRETPVELEFTQIEKI
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: IF172_HUMAN
Sequence: MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQEREFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ
What is the function of this protein?
Required for the maintenance and formation of cilia.  Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity).
What are the official names of this protein?
Intraflagellar transport protein 172 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT172 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Localized to the axoneme and around the base of the cilium.
Protein: KIF2A_PONAB
Sequence: MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPPRDNRVVGSARARPSQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKEFGISPSDIPFSQGSGSRPDLSPSYEYDDFSPSVTRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
What is the function of this protein?
Plus end-directed microtubule-dependent motor required for normal brain development.  May regulate microtubule dynamics during axonal growth.  Required for normal progression through mitosis.  Required for normal congress of chromosomes at the metaphase plate.  Required for normal spindle dynamics during mitosis.  Promotes spindle turnover.  Implicated in formation of bipolar mitotic spindles.  Has microtubule depolymerization activity (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF2A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1 (By similarity).
Protein: HSM3_CANGA
Sequence: MEQVFLEINEKLPGLLTTGGSDATFAESSKLIERCNLALISFTGTPTAVMDDTIKLMKSILASNESYNIDYDQLMDLMSQMVIKYPFDRILELFTVEELALALNSPIERLNIMTCVVVEYSEPSGLFASTTLIDILLQKYLDEDSSVNLVNSIEKVWKKTAQDELIRRRILENNYNFLSEVKNNEPNSLVFTRLLELLKICFTYLKSTEFRNSLFLISKKMIMDAVKDNILVFISICEYFTSIFSIVQDQKSQNPSKIICVRNCENTIMLFGDLFQNRSEFPDIEQFALSYLFKMFKILSYFDDLIVFEKLDNGYIHIEDGNEYLTDFLSFISPQYLYKKHLNIIKSKGHVRPSEISIIRNLCMSSDCFDIIKKNITAEDILAMPYLEQMILLEKMSQYDYSVKFLAQHLPKVMGSLISKDVKELLDRETFDFRLQVINNLIEWDVEQLHIWYEPLTEAKAQCMGTFASKDVGTKIESSFS
What is the function of this protein?
Involved in DNA mismatch repair in slow-growing cells.  Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC) (By similarity).
What are the official names of this protein?
DNA mismatch repair protein HSM3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
What are the subcellular locations of this protein?
Cytoplasm.