PharMolix/UniProtQA huggingface dataset:
Protein: GAB4_HUMAN
Sequence: MSLPSPSPSRELCPPDPAFAPLSSWPGSGPAGGSTRSGHVLYSGWLRKSPPEKKLRLFAWRKRWFILRRGQTSSDPDVLEYYKNDGSKKPLRTINLNLCEQLDVDVTLNFNKKEIQKGYMFDIKTSERTFYLVAETREDMNEWVQSICQICGFRQEESTGFLGNISSASHGLCSSPAEPSCSHQHLPQEQEPTSEPPVSHCVPPTWPIPAPPGCLRSHQHASQRAEHARSASFSQGSEAPFIMRRNTAMQNLAQHSGYSVDGVSGHIHGFHSLSKPSQHNAEFRGSTHRIPWSLASHGHTRGSLTGSEADNEASSGKYTQHGGGNASRPAESMHEGVCSFLPGRTLVGLSDSIASEGSCVPMNPGSPTLPAVKQAGDDSQGVCIPVGSCLVRFDLLGSPLTELSMHQDLSQGHEVQLPPVNRSLKPNQKANPTPPNLRNNRVINELSFKPPVTEPWSGTSHTFDSSSSQHPISTQSITNTDSEDSGERYLFPNPASAFPVSGGTSSSAPPRSTGNIHYAALDFQPSKPSIGSVTSGKKVDYVQVDLEKTQALQKTMHEQMCLRQSSEPPRGAKL
What are the official names of this protein?
GRB2-associated-binding protein 4, GRB2-associated binder 2-like, GAB2-like, GRB2-associated binder 4, GRB2-associated-binding protein 2-like, Growth factor receptor bound protein 2-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the GAB family.
Protein: Y032_BORBU
Sequence: MKEVDENSNVELFEVKLKPILGIEPKVYVFLTTIILLLSLISTLIIIPKFKNPGAYLKINSNIENTYIYLNEKYIGRTPLNKYINATEGVLRAKRMGFKTYEQRIKIHNKFFGNYSLQINLELVDPEKIIKQRQKELSIMVKIKNINENTKLIPVFSLISSELKEHPKYIKKFLKDSIPYLNSTEMFKDFLNSYKAIYSIDQDNSNQEEIWNSLKTNFDLENRAIFWFLENLDKDLKILTKNAPWVKTLAKTLDNENIQLISKNEKINIKLPGFKKINSNKIEKIQNYELNSLDSKNISLKSTYNVKEFLIQEQNVTKYEYQDFLKENPKWALNNKENLIKEQLVDENYLKNFNQIGLNEAITGISYFSAIEYANWYSKKLPTGFKARLPISQEWELYQKEPNKNPLNINEISKKVGFWNLMQNSSFNEIAIFKNEKNFYSENSNFYSLITEIRTYSQQNNNLLNASTKASFLKNWSSPNIGFRLIVSKE
What are the official names of this protein?
Uncharacterized protein BB_0032.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FLPA_PYRHO
Sequence: MVEVKKHKFPGVYTVIDDDGSERIATKNLVPGQRVYGERVIKWEGEEYRIWNPNRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGKIFGIEFSPRVLRELVPIVEERRNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKRGGYGMIAVKSRSIDVTKEPEQVFREVERELSEYFEVIERLNLEPYEKDHALFVVRKT
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: SYR_PSEA8
Sequence: MKDTIRQLIQQALDQLTADGTLPAGLTPDIQVENTKDRSHGDFASNIAMMLAKPAGMKPRDLAARLVEAIPAHEQLAKVEIAGPGFLNFFQDHVWLAASLDRALADERLGVRKAGPAQRVVIDLSSPNLAKEMHVGHLRSTIIGDAVARVLEFLGDTVIRQNHVGDWGTQFGMLLAYLEEQPIDAEAELHDLEVFYRAAKKRFDESPEFADRARELVVKLQAGDPDCLRLWTRFNEISLSHCQKVYDRLGVKLSMADVMGESAYNDDLAQVVADLTAKGLLTEDNGALCVFLEEFKNAEGNPLPVIVQKAGGGYLYATTDLAAMRYRHNVLHADRVLYFVDQRQALHFQQVFEVARRAGFVPAGMELEHMGFGTMNGADGRPFKTRDGGTVKLIDLLEEAESRAYALVKERNEQRAERGEEPFDEVQLREIGRVVGIDSVKYADLSKHRTSDYSFNFELMLSFEGNTAPYLLYACTRVASVFRKLGQGREQLGGKIVLEQPQELALAAQLAQFGDLINNVALKGVPHLLCAYLYELAGLFSSFYEHCPILTAEDPAQKDSRLRLAALTGRTLEQGLELLGLKTLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_ECOK1
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAGK_YERPS
Sequence: MYYGFDMGGTKIELGVFDENLQRIWHKRVPTPREDYPQLLQILRDLTEEADTYCGVQGSVGIGIPGLPNADDGTVFTANVPSAMGQPLQADLSRLIQREVRIDNDANCFALSEAWDPEFRTYPTVLGLILGTGVGGGLIVNGSIVSGRNHITGEFGHFRLPVDALDILGADIPRVPCGCGHRGCIENYISGRGFEWMYSHFYQHTLPATDIIAHYAAGEPKAVAHVERFMDVLAVCLGNLLTMLDPHLVVVGGGLSNFEKIYQELPKRLPAHLLRVARLPRIEKARYGDSGGVRGAAFLHLAEK
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: IOLE_BACAH
Sequence: MFKENTIKLGIAPIAWTNDDMPELGAENTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLELRNLEIASAWFSTFLTTKPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDITDSALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDIVKENELSFLQAVKNGAFTVPGDGVIEFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKAREFIREKAGL
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: YGFB_SALTY
Sequence: MSIQNEMPGYNEMNRFLNQQGAGLTPAEMHGLISGMICGGNNDSSWQPLLHDLTNEGLAFGHELAQALRKMHAATSDALEDDGFLFQLYLPEGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDESEDQEELEMSLEEIIEYVRVAALLCHDTFTRQQPTAPEVRKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: DXS_SHEPW
Sequence: MSFDISQFPVLAQANTPDELRQLPQAVLPQLADELRGFLLKSVGKSSGHFASGLGTVELTVAIHYVYNTPFDRLIWDVGHQAYPHKILTGRRERMHTIRQKGGVHPFPWREESEYDTFSVGHSGTSVSAALAMAVAAEKEQAGRKVVSVIGDGAMTGGMVFEAMNHAGDLHNDMLVILNDNEMSISENVGALNNHLAQLMSGRFYTTIRENSKKVLKGMPVIKEMAKRTEEHLKGMVVPGTMFEELGFNYIGPIDGHDVDALVETLRNMRNLSGPQILHIMTKKGRGYEPAEKDPIGWHAVPKFDPSTFEKPASKPSDPTFSQVFGKWLCDVAEKDEKLLAITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLGAGFACEGYTPVVAIYSTFLQRGYDQLIHDVALQKLPVVFAIDRGGIVGADGPTHQGAFDLSFMRTVPNMVIMAPSDENECRQMLYTGYCYKAGPTAVRYPRGSATGAKQVETMTALPIGKGLIKRQGQKIAILNFGTTLANSLVAAEAFDATVADMRFVKPLDVDLIKELAETHDVLVTVEENAIMGGAGSGVLELLQTLKLPKPVLQIGLPDEFIKHGAPDEIISELRLDAAGIEKQIADYLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: GCSP_THEVB
Sequence: MMVSSPPQLEINLETDAEFVARHIGITPSDLPKMLSLLGYGSLKELINAVIPPEIRLQRPLALSEGLSETAALQKLRTLAQQNQVWRSYIGMGYYNCITPSVIQRNILENPGWYTQYTPYQAEIAQGRLEALLNFQTLVSDLTGLAIANASLLDEATAAAEAMTLSFNACRQRGANRFLVAQDCHPQTLAVLRTRALPLGIQIVPIDPIAGELPWENAFGLLLQYPASDGAVRSPQALIAAAHERGLLVTVATDLLALTLLRPPGELGADIAVGSSQRFGVPLGYGGPHAAFFATREDFKRQLPGRLVGVSHDALGQRALRLALQTREQHIRREKATSNICTAQVLLAVVASMYAVYHGPDGLRQIAERIHQRTVRLAAGLEAAGYQLYYSEFFDTLRIGLGNLPVPVLKERAAAARINLRYFDDGSAGISLDETTTEKDVADLLALFGARPAEVEGGDRLPAALKRQSPYLQHPVFQDYHSEHALLRYIHRLQAKDLSLTTSMIPLGSCTMKLNATAEMLPISWPEFNQLHPFAPQEQAQGYQALFRELAAMLAEITGFDAISLQPNAGSQGEYAGLLVIRQYHHSRGESQRNVCLIPTSAHGTNPASAVMAGMQVVAVNCDAQGNIDVADLAAKAETYGDRLAALMITYPSTHGVFETGICQICDIIHRYGGQVYMDGANMNAQVGLCRPGDFGADVCHLNLHKTFCIPHGGGGPGVGPIGVKAHLAPFLPTTQVIPQGSETGPVTAAPWGSASILPISWMYITLMGGVGLTRATAIAILNANYIAKRLEPYYPVLYKGAHGLVAHECILDLRPLKKSAGIEVEDIAKRLMDYGFHAPTVSWPVPGTLMIEPTESETKAELDRFCEAMIAIRSEIAEIEAGVSDRQQNPLKNAPHPALMLATEPWPYPYSREVAAYPAPWLREYKFWPAVARIDNAYGDRHLVCTCSMPLTN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MHT_BOMMX
Sequence: ILGPVLGLVGNALGGLIKNE
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Maximin-Ht, Maximin-7.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_BACC7
Sequence: METTVRKQKKNLETKKPSIYSLQLHEMQDWLKEQGEPKFRAGQIFDWLYKKRVKNYEDMSNLSKGLREKLSNSFDITTLNTLVKQTSSDGTIKFLFQLYDGYSIETVLMRHEYGNSICVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVAQVVEVQRALDESEERVSSLVVMGIGEPFDNYDNLMGFLRIINHEKGLHIGARHMTVSTSGIIPKIYKFAEEDLQINFAISLHAPNSELRSKLMPINRAYKLPDLMEAIKYYVNRTGRRITFEYGLFGGENDQVEHAEELAALLKGVKCHVNLIPVNYVPERDYVRTPREQIFLFEKTLKDRGVNVTIRREQGHDIDAACGQLRAKERKEETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_LEPCP
Sequence: MSLNRNDKAAVVAEVAAQVARSQTLALAEYRGLTVADLDKLRRTAREQGVYLHVLKNTLARRAVAGTAFESAAESMSGPLIYGFSEDAIAAAKVVVDFAKTNDKLVLKGGAYAGKALDVNGIKALASIPSKEVLLAQFLGLLQSPISRTARVLAALAEKRAVPAAEEAVEATADVATEAAAG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: VP4B_RRSVT
Sequence: MPSVRASDPKQQLYPIAELEQLSQEDVRNIAKTHRSPTLLRTQTKFCVGRRGELSYDTTLAPLQYSEPGDSILRGSDKQDGNDSSLSILSRLWCYGVSRRKAQASEIDSELVARGISKVLEDSHAKLDGFGSHQLYDSQTYNDYYSRSAGNQISERGEGGERSNLFIAVHKPRHPQSYQPVSDPSVLAGYESVRERRDVFRFGGGTNFEQGGSTENRGNYSEIPELTLLNYEQGTHSSLITERDGYKFWSGMSICETIYTATRDEIEEYELSRGIHSVPNIIELRQRLRRRSHRNYDANHSTSGEEENSGSRSRIAELSQSTIHRR
What are the official names of this protein?
Uncharacterized protein VP4b.
Protein: LEU1_ALISL
Sequence: MSDQVIIFDTTLRDGEQALSASLTVKEKLQIAFALERLGVDVIEAGFPISSPGDFESVRTIAKHIKNSRICALSRAVTKDIDVAADALKVAEAFRIHTFISTSTVHVQDKLRRSYDDVVEMGVKAVQRARKYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGANTINIPDTVGYTIPGEFGGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAVQAGARQVEGTINGIGERAGNCSLEEIAMILQTRSEYLGVHTSLKNDEIHRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNKALNLTSRSGRAAVKSHMDSMGYKAEEYNLDTLYADFVKLADRKGQVFDYDLEALMHFANLRDEDDFYKLNYLSVQSGSVMATTSIKLLCGDEEKCEAAVGNGPVDALYQCIYKLTGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGLATDIIEASGQALLHVINSIHRADQIAEIKQNKITTV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: AMPA_RHILW
Sequence: MSAKFEISFSKSAKLTGGLAILLKTTDADSAAGAETVDPAGVIAKAARIARFSAKSMSALDIVAPEGASVERIVVIGLGKAADLTAHDWLKAGGTAAARIKNTDKTAVFIDVPGRETSARAAADFALGMLLRTYSFDTYKTKKNDDEEKAGKSVKVTIVTTDPAGAKKAFSDSEAIAGGVNLARDLVNEPPNVLGPVEFAAKAKELEKLGIEVEILTEKEMRRFGMGALLGVAQGSVRPPRLAVMQWKGGKAKDRPVAFIGKGVVFDTGGISIKPAAGMEDMKGDMGGAAAVTGLMHVLASRKAAVNAVGIIGLVENMPDGNAQRPGDIVTSMSGQTIEVINTDAEGRLVLCDALWYCNDRFKPQFMINLATLTGAIVVALGNVHAGLFSNDDQLSAQLTEAGLSTNEKLWRMPLGKDYDKLIDSKFADMKNTGGRQAGSITAAHFIKRFVQDTPWAHLDIAGTAMGSPQDEINQSWGSGFGVRLLDELVRAHYES
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMF_ECOL5
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERYNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFANGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPTPKYKVGNFPFSPVKDREAGQIRQAAASVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPHAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTGNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_JANMA
Sequence: MPTINQLIRQPRVSARVKSKSPALENSPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLLRGGRVKDLPGVRYHMVRGALDTQGVKDRKQARSKYGTKRAKAGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: YC16_YEAST
Sequence: MVTFNCEVCNDTVPKKNTEKHYYRCPNAYYTCIDCSKTFEDGVSYKNHTSCISEDEKYQKALYKGNKKQKQKQQQKQQQKQHQHQPVATPAKKVEKPVIKKAEKVEKTSNGIELHKGKSLYKILKTMKDKGAKKTFLKSLVVDSEGQIRYAKE
What are the official names of this protein?
UPF0743 protein YCR087C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0743 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DEP1_SCHPO
Sequence: MTENLQSESIPHEILPKEPFDLPMNNLKSSPKNKDSEKRINNSIAESEQVVDSALSNPETNANEDIIAPQLPSQNSEIIEKNSPVNKLNSSTSLTTHQLASLPKLEVTDHDNVSEAETVVLNEDEEKETSLVGSVSVTEDLGDSSAIGRTILVNNSVEPQMENTANITIVSPSLKESDFESEEKATNDNNGLIETNHNSKLEESSEHEEEEDEESNIERTEDSDHQIPQRGGTLEAPRKGGPRSGVGSRKRKRATVSRKWSTNSESKIKRVALETSQEESDREIADRRSASEQAHEADDEKAIKRKEAFDALLNIETEFTFLRNRLYGKKLLKLNEHEEMIQNETHERFNACIDLITERRDDRVRLATENLMKQLGNIKNVMDYVTKQRKYQLLFDKRRIRQALLTKIATKCFQLLNKQKSVHDPTYITQKTMSYRQSALLQKQRIEYEAAVLCELNSFAGFPTAPIIETASFDDIRNDLLEMGCLSENQD
What is the function of this protein?
Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein dep1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAPT_ECOLI
Sequence: MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCSTITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLELVQNPDYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVISVDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKTQHLGSITAEQLESV
What is the function of this protein?
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 47 of tRNAs (PubMed:31804502, PubMed:31863583, PubMed:4597321).  Acp3U47 confers thermal stability on tRNA (PubMed:31804502).
What are the official names of this protein?
tRNA-uridine aminocarboxypropyltransferase, SAM-dependent 3-amino-3-carboxypropyl transferase, tRNA U47 acp transferase A, tRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. DTWD2 family. TapT subfamily.
Protein: YCIB_PSEA8
Sequence: MKQFIDFIPLILFFIVYKIDPQNVEFAGFNLSGIYGATATLILASVIVYGALWLKHRHLEKSQWFTLGACLVLGGLTLAFHEDTFLKWKAPLVNWLFALAFAGSHFIGDKPMIQRIMGHAIQLPQGLWVRLNIAWVVFFLVCGFANLYVVFTYPNFWVDFKVFGSLGMTLLFLIGQGLFLARHLHDADTGEKPKD
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_CAUVC
Sequence: MTKLNELAPREGSTKGRMRVGRGPGSGKGKTAGRGVKGQKARSGVAINGFEGGQMPLHMRMPKRGFNNPFRLEFAEVNLWRLEQAVEAGKIKKGAELDAAALIAAGVIRRELDGVKLLAKGEIKTALKLTVYSATEAAIKAVEAAGGSVTVTKKAKAQAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL27_PROMM
Sequence: MAHKKGTGSTRNGRDSNSKRLGVKAYGGETVTAGSILIRQRGTSVLPGVNVGQGKDDTLFALTDGVVAFESIRRSLRNRKRISVVASS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SHO1_SCHCM
Sequence: MPPRGNEGLDFTPIITHYLFLFTSILAFIAWFTAFIGQIIATARWNGPVGTLWFAIFLHLFLILGVLYTLASDSLATHRFQISVFGAVALVFAVNGANAGLYAEDGALNAMAAGYLILAIVDILWLLFFTAEEESLLFHLFNRLGTGGLTPPSRRRRARSVHNMAPANGYASGGYGAGGGISSHDVATGAYDAKPVSGAFDARSGTASGAFDNKSAGAGAGLNSPGGGARSQHSLGGPTTATGSVHSPRGEDGTGSPLMAQGDMSGAGTSGEFLPKAKALYAYTASPDDPNEISFAKGEILEVTDKSGKWWSARKADGTNGIAPSNYLQLL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM121_MOUSE
Sequence: MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT
What is the function of this protein?
May play a role in MAPK signaling.
What are the official names of this protein?
Transmembrane protein 121, Protein hole.
What is the protein family that this protein belongs to?
Belongs to the TMEM121 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=May localize to the plasma membrane.
Protein: U333_DORVU
Sequence: MSKVILLCLIFALFACSISALSKNKNCLKLGQKCNFEKKRCCTGLNCYISQNKCLPVKL
What is the function of this protein?
Probable toxin.  Shows a relatively potent antiparasitic activity against the major pathogenic nematode of ruminants (H. contortus, EC(50)=2. 6 uM).  Does not show insecticidal and antimicrobial activities.  Does not induce increase in intracellular calcium in mouse DRG neurons, suggesting that it does not induce pain.
What are the official names of this protein?
U-limacoditoxin(3)-Dv33, U-LCTX(3)-Dv33, Cecropin-like peptide, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_BLUHO
Sequence: MGDSKCPYRDANVAGGGTHNKDWWPETLKLDALRQHTAESNPLGKDFDYASAFKTLDYEGLKKDLKDLMTDSQDWWPADFGHYGGFFVRMAWHSAGTYRSIDGRGGGGQGQHRFAPLNSWPDNGNLDKARRLLWPIKQKYGNKISWADLYLLTGNVAIESMGGKTFGFACGRPDTWEADDATFWGNETKWLGNDARYKNGSKDPKDIYTRQLEKPLSAVHMGLIYVNPEGPDGIPDPVASARDIRTTFRRMAMNDEETVALIAGGHTFGKTHGAAPATHLGKEPEGAPIEAQGLGWANSYRSGKGPDTITSGLEVIWTKTPINWSNHYLEYLFKYDWELTKSPGGANQWTAKNAEAFIPDAFDPNKKHPPRMLTTDLALRHDKEYEKISLRFLENPDQFADAFARAWFKLLHRDMGPRSRWLGPEIPKEELIWEDPIPEIDHPIISQEDINNLKKEILSSGVGHNKLIQTAWASASTFRGGDKRGGANGARIRLAPQKDWKVNNPPQLTCVLETLGKIQSSFNSSQTGGKIVSLADLIILAGCAALEKAAGVPVPFSPGRADASQEQTDIKSFSNLEPVADGFRNFGRSTPRARAEHMLVDRAQLLTLTPPELTALVGGLRVLDTNFDGSSCGVFTKRPGQLTNDFFVNLLDPAISWKGIDEDEFFEGIDRKTDEKKWIGSRADLVFGSQAELRAIAEVYGSADGNEKLIKDFIAAWNKVMNLDLFNLAH
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_HAEI8
Sequence: MNKTNPTIALVAGEVSGDILGAGLIRQLKAHYPNARFIGIAGTRMLAEGCKTLVDMEELSVMGLAEILKHLPRLLKIRKNVIQTMLQEKPDVYIGIDAPDFNLDVELKLKANGIKTIHYVSPSVWAWRQNRIHKIAKATHQVLAFLPFEKAFYDKFNVPCRFIGHTMADAIPLKPNRAEACQMLQIDPAQRYLAILVGSRGSEVEFLAEPFLKTALLLKEQFPDLQFLVPLVNEKRRIQFEAIKAKIAPNLDLHLIDGNARQAMIAADATLLASGTAALEAMLCKSPMVVGYRMKPLTYFLAKRLVKTDYISLPNLLANEMLVPEMIQEECTPELLAEKLSAYLSDDESAVKNRHILIQHFTDLHQKIQCNADKQAAQAVIDLLEGTENV
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: Y908_STREM
Sequence: MSDHYHYPLDASWSTEEITSVLHFLNQVELAYEAKVRAEELLKSYAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR
What are the official names of this protein?
UPF0223 protein Sez_0908.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.