PharMolix/UniProtQA huggingface dataset:
Protein: GARE1_HUMAN
Sequence: MDPAPSLGCSLKDVKWSSVAVPLDLLVSTYRLPQIARLDNGECVEGLRENDYLLIHSCRQWTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERVYVMEDITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKKIGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIVEKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLHLTVPKFSLPEHLVKGESWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEECKSPKKGRCSGHNHVPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGDWAPFPHDILPYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNISVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASYPFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVISFFVTEKIDGNLLVQLTEEILSEDFKLSKLQVKKIMQFINGWRPKI
What is the function of this protein?
Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases.  Promotes activation of the MAPK/ERK signaling pathway.  Plays a role in the regulation of cell proliferation.
What are the official names of this protein?
GRB2-associated and regulator of MAPK protein 1, GRB2-associated and regulator of MAPK1.
What is the protein family that this protein belongs to?
Belongs to the GAREM family.
Protein: DHLO_AGRVI
Sequence: MAKVAILGAGNLALTLAGDLARRLGQTPSIWAPISNRSSFNDVRCLGSLELVGPDYGGDFQPRLEDDLGTAISGAAFIFLTVPTLGQQGILRELAKFNLSNSVLVALPGSATSLACKQTLVPTFAPIAVIESTTSPYACRRVKARVLMLGVKATFEVATTQPLSEEVKGRFEVLFPNPPQWYQHPASIFFSNTNPVAHPAGILAARDSIEQGILPVPKFYRQFVPQAITRVIAIDEERLSIVDALGLESETDFSYSKKWYGGHACNAREFYETYEGYAEIETPKTMNHRYLTEDVKHILVLWVEIAEAIGVQVPEMKSVVQEASDVLNENLLRTGRGLSSLNLGGANANAIVRALNGV
What is the function of this protein?
Reductive condensation of pyruvate and arginine, lysine, histidine, or octopine to form octopine, lysopine, histopine, or octopinic acid, respectively.  NADPH is the preferred cofactor, but NADH can also be used.
What are the official names of this protein?
Protein ocs.
What is the protein family that this protein belongs to?
Belongs to the lysopine/nopaline/octopine/opine/vitopine dehydrogenases family.
Protein: COBT_SALA4
Sequence: MQTLHALLRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTRGTTGVCVLAAQAGAKVYVIDVGIDAEPIPGVVDMRVARGCGNIAVGPAMSRSQAEALLLEVSRYTCDLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGGFDLVGMTGVILGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAMFHNMGELAASNIVLPEGNANAT
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RS5_PYRIL
Sequence: MSVVDLSLWEPRTELGRLVKEGKIRTIDEIFANNYIIKEPEIVDILLPGLKQEILNINVVQRQTHAGERSQFQVVVAVGNEDGYVGVGIGKAKQVRQAIEKAVREAKLNLTPVRRGCGSWKCSCDEPHSVPFVVRGKSGSVEVTLIPAPKGVGLVAGDVAKVVLRLAGIKDVWTQTRGDTRTTLNFAMAVYNALRNTYYFKI
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RFAY_SALTY
Sequence: MIIEKKIKNYTVFVKKDGEKYIEIFKDFLSYNHQVIKVFRNIEDTKVVLINTDYGKYILKVFSPKVKNTERFFKSLVKGDYYEKLFHQTDRVRREGFAALNDFYLLAEIKTLRYVKTYVMIIEYIEGIELVDMPEISDEVRGKIKQSIYSLHQHGMVSGDPHKGNFILQGNEIRIIDLSGKRPSRQRKAKDRIDLERHYGIKNNVRDIGFYLLIYKKKLRNFLRRIKGKEKR
What is the function of this protein?
Catalyzes the phosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II) kinase RfaY.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. RfaY/WaaY family.
Protein: SCAF_HHV6Z
Sequence: MSKVWVGGFLCVYGEEPSEECLALPRDTVQKELRSGNIPLPLNINHNEKATIGMVRGLFDLEHGLFCVAQIQSQTFMDIIRNIASKSKLIAAGSVIEPLPPDPEIECLSSSFPGLSLSSKVLQDENLDGKPFFHHVSVCGVGRRPGTIAIFGREISWILDRFSCISESEKRQVLEGVNVYSQGFDENLFSADLYDLLADSLDTSYIRKRFPKLQLDKQLCGLSKCTYIKASEPPVEIIVATGKVAGDQVQLTTEPGSELAVETCDVSVVHGNYDAVESATATTAMSNQNLPNTTPLLSSPPFSDCVFLPKDAFFSLLNVTTGQQPKVVPPVSVHPPVTEQYQMLPYSESAAKIAEQESNRYHSPCQTMYPYWQYSPVPQYPAVLHGYRQPKTFKKRHFQSDSEDELSFPGDPEYTKKRRRHKVDNDDDKEMAREKNDLRELVDMIGMLRQEINALKHVRAQSPQRHVVPMETLPTIEEKGAASPKPSILNASLTPETVNRSLAGQNESMDLLKLNKKLFVDALNKMDS
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: SOMA_PANGG
Sequence: MARVLVVLSVVVASLFFSQGATFENQRLFNNAVIRVQHLHQLAAKMMDDFEEALLPEERKQLSKIFPLSFCNSDSIEAPAGKDETQKSSVLKLLHTSYRLIESWEFPSKNLGNPNHISEKLADLKMGIGVLIEGCLDGQTSLDENDSLAPPFEDFYQTLSEGNLRKSFRLLSCFKKDMHKVETYLSVAKCRRSLDSNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAO1_IDILO
Sequence: MPQTQRPLYIPYSGPNLLETPLLNKGSAFSKEERAAFNLTGLLPPRYESIEEQAERAYMQYRSFETPINKHIYLRAIQDNNETLFYRLLTDHLEEMMPIIYTPTVGDACEKFSDIYRSSRGLFISYSERDQIDDILRNATKQKVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVMLDVGTNNEKLLEDPMYMGARHKRIEQDEYDEFLDKFIKAVTRRWPGVMLQFEDFAQPNAMPLLRRYRDEVCCFNDDIQGTASVTVGTLLAACRQKGKKLSEQKVVFVGAGSAGCGIAEQIMIQMTAEGLTEEQAKRQIFMVDRFGLVMDTMDGLRDFQQALAQKTSDLNAWEYSGEYPSLLDVMHCAEPDILIGVSGQAGLFTEQVISTMAKNVERPIIFPLSNPSKHVEAHPADVLKWSEGKAIVATGSPFGEVEYDGRIYPIAQCNNSYIFPGIGLGVLSVKSERVSDEMLRVASKTLANASPSANGKGEALLPAFNDLTQLSKDIAFAVGKVAQQEGLALEIDDDTLRERIDNNFWKPEYRFYKRVSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: PLSX_NITEU
Sequence: MNITVAIDCMGGDHGPHITVPSAVEYMHHDCETNIILVGKPEVISRELDALKVSPGSRLRLHPANEVVGMDEHPAVALRNKKDSSMRVALNLIKSGEAQACISAGNTGALLATSRFVLKTIPGIDRPALAVILPTISGHTYVLDLGANVNCTAEHLLQFGIMGATLVSSVENKPNPSIGLLNVGEEDIKGNDVVKRAAELFRSSGLNFYGNIEGDDIYRGTTNVVVCDGFVGNVALKTSEGLAQMLASYLREEFRRSLFSRLAGLVALPVINAFRRRVDHRQYNGASLLGLRGVVIKSHGSADSYAFRCAIRRAVEEVRGGTLRNIVEHIETLRNNIEQNIAQPVSIE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MENH_YERPB
Sequence: MTTLACQKLAPHPESPRHQHAGPWLVWLHGLLGSGQDWLPVAQLCGDYPSLLIDLPGHGQSVSLSADGFADISRQLSQTLQANGIREYWLAGYSLGGRIAIYHACYGRHHGLQGLLVEGGNLGLENAELRQARLQQDRQWAQRFRQEPLPQVLDDWYQQAVFADLDPQQREQLVLLRADNHGPAVAEMLEATSLGHQPWLLPALQRLNVPYTYLCGDRDHKFLQLAQQYRLPLHTLARAGHNAHRANPGAFAAQVLAFLSQSSCLPPSSLSR
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: GREA_HAEIN
Sequence: MQQIPMTVRGAEQLREELDFLKNVRRPEIIKAIAEAREHGDLKENAEYHAAREQQGFCEGRIQEIEGKLGNAQIIDVSKMPNNGKVIFGATVVLVNTNTDEEVTYRIVGDDEADIKSGLISVNSPIARGLIGKELDDTVNITTPGGVVEFDIIEVNYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides (By similarity).
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RNPH_SHEON
Sequence: MRPSNRTPAQTRPITITRQFTAHAEGSVLVEFGETKVLCTASFTEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMDREAARGKQSGRTQEIQRLIGRALRACVDMKALGENTIVIDCDVIQADGGTRTASITGACVALVDALNWARGKGIIKSNPLKFLIAAVSVGIYNGEAISDLEYVEDSAAETDMNVVMTETGKIIEIQGTAEGEPFTHEELIELLGLAKNSIREIVDVQKAALN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: DNAK_RHOMR
Sequence: MGKIIGIDLGTTNSVVAVMEGGEPKVIINPEGSRVTPSVVAFTADGEPLVGAPAKRQAITNPKNTIFSIKRFMGRFYDEVTEEISMVPYKVVRGENNTVRVEVEVGGEKRLYTPQEISAMILQKLKQTAEEYLGVPVTEAVITVPAYFNDAQRKATKEAGEIAGLKVRRILNEPTAAALAYGLDKKDKELKIAVYDLGGGTYDISILELGDGVFEVKATNGDTHLGGDNFDQRLIDYIADEFQKQEGIDLRKDPMALQRLKEAAEKAKIELSSAMKTTVNLPFITATAEGPKHLVMEITRAKFEQLIEDLVARTIPPMEQALKDAKLRKEDIDEVILVGGSTRIPLVQRTVEEFFGKKANKSVNPDEVVAIGAAIQAGVLSGEVQDVLLLDVTPLNLGIETLGGVMTVLIPANTTIPTRKSEIFTTASDNQTSVEIHVLQGNREMAADNRSLGRFILDGIPPAPRGVPQIEVTFDIDANGILHVSARDKATGKEQSIRIEASSGLTPEEIERMREEARRHAAEDRKRREQIEKLNQADSLIYMTEKNLREYGDKLPADKRAKIESALERLKEVHKARNFDELDSAIAQLNQAWNEASQDLYRAQQAAGAQTSDGASAQADSGGVREADYEVIDEDDKDKQ
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DUS3_DEBHA
Sequence: MSNIPEKRPSEQPDEAEAKKPHIEPRHDHFAKGIAPIKAEFIVENPDVPVEEKYINDDEAEGGDRQEEEGGKGGKNKKRRGQNKKRDLKQQHEEVRLCSSLLDPENPKECRFGAENCRNSHNVEEYISSKPEDIEGNCPVYTAIGYCPAGLKCRWLHSHYNKETHKLLKDLEQVENAKALNNYEVNKITPDKKTSLQKKKYTFEYASQMIPYLDSLVQNEANIEKAQEQAKENQSTFVEAPFKVAEKKKLNLRDAKIVSPLTTVGNLPYRRLMKTLGADVTYSEMALSVPLLQGTNAEWALPKAHRTEYPGYGVQIATSKHWAAAKAAEAIYKEATHVSELNLNCGCPIDLLYRQGQGSALMEQPARLLRILKGMNASSGDIPVTVKIRTGTKENKNTAKALVERILSENEVAAITLHGRSRQQRYTKEADWSYVQDVANIVQDWNNKKEDNKELRDTQPTCFVGNGDVYTHEDWYNAVNIPGVDSVMVARGALIKPWIFEEVEAQQYLDKSSTERLEMIGQYAKFAIEHWGSDEYGVGLARRFMCEFLGFTHRYIPVGILERLPPKLNQRPPQWKGRDELETLLGSTDYKDWIKITEMFLGKAGPNFQFVPKHKSNAYEKS
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IMA5_CHICK
Sequence: MTTSGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEEAEEEVMSDGGFHEAQMNNMEMTSSAVITSDMIEMIFSNSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFEAAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLLSKQNRITMTRNAVWALSNLCRGKNPPPDFAKVSPCLSVLSWLLFVNDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDAHIFPALINILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALSGLENILRLGEQESKRSGAGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLSQQQYIFQQCEAPMEGFQL
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Importin subunit alpha-5, Karyopherin subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCL2_MACFA
Sequence: MKVSAALLCLLLIAATFSPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQIQTPKP
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_THEAC
Sequence: MGDPKFHHKKYSTPRHPWEKERIDEENKIVVKYGLKNKKEIWRSEALLSSIRSQARDLRARLRTNDVNAQKQLERMIKRLNRYKLLSENATLDDVLSLTVENILDRRLQTIVFRKNLAISVRQARQLITHGHISVAGRRVTVPGMLVEAKDEDTIAYEENSPVANELHPIRQALLAPAQRSAEMKEGQGEASEEGETDE
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TRPDH_NOSP7
Sequence: MLLFETVREMGHEQVLFCHGKNPEIKAIIAIHDTTLGPAMGATRLMPYVNEEAALKDALRLSRGMTYKAACANIPAGGGKAVIIANPENKTDDLLRAYGRFVNSLNGRFITGQDVNITPDDVRTISQETNHVVGVSEKSGGPAPITSLGVFLGIKAAVESRWQSKRLDGMKVAVQGLGNVGKNLCRHLHEHDVKLFVSDVDPAKAEEAKRLFGATVVEPTEIYSLDVDIFSPCALGGILNSHTIPFLQAQIIAGAANNQLENEQLHSQMLTRKGILYSPDYVINAGGLINVYNEMIGYDEEKAFKQVHNIYDTLLAIFDIAKEQGVTTNDAAKRLAEDRISNSKRSKSKAIAA
What is the function of this protein?
Catalyzes the reversible oxidative deamination of L-tryptophan to indole-3-pyruvate in the presence of NAD(+) (PubMed:18954141, PubMed:25615944).  Cannot use other L-amino acids and D-Trp (PubMed:25615944).  Involved in the biosynthesis of scytonemin, a cyanobacterial radiation-absorbing pigment (PubMed:18954141).
What are the official names of this protein?
L-tryptophan dehydrogenase, L-Trp dehydrogenase, TrpDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: TYSY_METSB
Sequence: MQAYLDLIDKILREGVRKPDRTGTGTLSIFGYQMRFDLGAGFPLVTTKKLHWKSIVHELIWFLRGDTNIGYLKDNGVGIWDEWADDSGDLGPVYGRQWRSWQAPDGRTIDQIANVIDEIQRDPFSRRLLVSAWNPADLPAMALAPCHCLFQFNVRDDSTGTRRLDLQLYQRSGDAFLGAPFNIASYALLTELVASVCGLTPGDFVHTFGDAHLYLNHIDQAKLQLSRDPRPLPRLRINGNVKSLFDIRFEDLSLENYDPHPVIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REC3_ARATH
Sequence: MAPRSSKGKSNNKGKGGDKKKRDDKLLAPSLVEITVTTPYETQVILKGVSTDKIIDVRRLLASHVETCHFTNYSLSHKVKGHKLNDNIQVLSLKPCFLRMIPEEYLEESQALTQVRRVIDIVACTTRFFSKSPNKSIVAGNANPTPAPDGLDMVAIHTTPKLSQFYEFFSIHHLSPPILHLKKVDGEEAGEKRDGDYFGLKVKICNGKVIHVIASVKGFFAVGKQLSHCHSIVDLLQNVSNAFAKAYESLMKAFTDRNKFGNLPFGLRSNTWLVPSPVSESASPLPTEDEHWGGNGGGQGRNGEYDHRPWAAEFSVLATLPCKTEEERVIRDKKAFLLHSQFIDTSVQRAVRAICNVMDTNQQTSGTTDLPAGSILLEDHVGDLSIVVKRDIASLDSKPEATFQNDAFVLSSEELAERNLLKGITADESVIVHDTPALGKVIVRQCGYTAVVNVKGQTQKAMSDFRDILIDDLPDGGANALNLNSLRVEFHRPHSVGTSVENQPTQLDWDDLESYRCIIQELVKINLTKLEETRVSSVRPIRWELGSTWVQHLQKKETDVCGKPATNDETELSVKGLGKQFKDLKSKSKKSENISAVNEKDTRLHELNEEDDLGQKSIDGLFTELKELLSEEAFSRLKETGTGLHLKSKEELTNMAYGYYDEIALPRLVADFGSLELSPVDGRTLTDFMHIRGLQMRSLGHVAKLAEKLPHIQSLCIHEMITRAFKHLLRAVIASVNNMAELPVAVAASLNFMLGRRELEGCDRIPGEEYCLRLQWLQKFLSRKFGWIQKDEFHHLKKFSILRGLCQKVGLELVSRDFDFDSPNPFMSSDIIGLVPVCKHVLCISSDGRTLLESSKLALDKGKLDDAVSYGTKALVKMIAVCGPYHRNTACAYSLLAVVLYHTGDFNQATIYQQKALDINERELGLDHPDTMKSYGDLSVFYYRLQHFELALKYVNRALFLLHFTCGLSHPNTAATYINVAMMEKEVGNDHLALRYLHEALKSNKRLLGADHIQTAASYHAIAVALSFMEAHSLSVQHEQTTLQILTAKLGADDLRTQDAAAWLEYFESRAIEQQEAGRNGIPKPDASIASKGHLSVSDLLDYISSDPDTKGNVAHRKHRRARILQVNDKVASADDDAHRVASQIDIVTWNNVAEADVTKSRSEVNDPDTVVDKTNIETGDIVVHRLNVDRQTVEESTLDEGWQEAYSKGRSGNGAGRKSRQRQPDLMKKRMLLNKHHNRNQDVQQQNIYSPLQKTSKGPSLSKSSPRRALKNAEIDVSTNTTKPQLKASGAAAVTSTTLASKSLSYKEVALAPPGTVLKPMLEKLELNLERTETQIYRTSSASSGEESKSDTVMLDLPIEGTELHCEKQESQESAESVENLTSESEGDLGSYRGKKTSDISRTKLSASAEPYNPGGFLVIDLQSSAATIGSYPIMVADPISWAVVSCGIHSPPYYSAIHSNGVGTPRSMNPDAPEFVPRRSLQNSSQHAGEDASVSVDSSSCLKAEKDAVDLKKRELASFIVKSSQKEVPAALSKTSPEAESGGTSEKDSAVTEIVYSREEENGANANETNGGEGFVIVAKKRRRKNKVRLTNVAAGLYHQPSSVCA
What is the function of this protein?
May act as the scaffold of a protein complex, which sequesters key factors that are required for the G2 to M transition in meristematic tissues (By similarity).  Together with REC2, REC3 and FMT/CLU, contributes to the establishment of the cellular volume devoted to the chloroplast compartment (PubMed:26862170).
What are the official names of this protein?
Protein REDUCED CHLOROPLAST COVERAGE 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: PPK1_ACIBA
Sequence: MNSVVTQASPPVYGQVERYINRELSILDFNLRVLEQAVDPLNPLLEKLNFLLIFSRNLDEFFEIRVATMLEHFVQERDIQTADGLSPQEILHQISETAHAAIERQYQILNEQIFPQLREEGISFLRRGELTQAQSNWVKKYFQEQVAPALTPISLDPAHPFPRLVNKSLNFIVTLEGKDAFGRQIDLAVVPAPHSLPRVVRLPDELTEGKEHHVMLSSIIHTHVSDSFPGMTATGCYQFRVTRNADLTLTEDVEDLAEALKDELSSRRFGRAVRLEVNKNCPTHIYEYLLKEFDLDTHQLYRVDGPVNLARLVSDFKRPYLRYEPHTPVIPKILKKSANIFSAMQKQDILLHHPFESFSPVIRLLREAAQDPHVLAIKQTLYRSGANSEIVQILAEAARNGKEVTAVIELRARFDEESNIAVANVLQEAGAVVVYGIVGYKTHAKMILVVRRENQKLVRYAHLGTGNYHAGNAKIYTDYGLLTTNQDLCEDVHRIFQELTGMGKMVKLKKLLHAPFTLHSQLMNFIENEIVLAKAGKPAKIIIKVNALTEVQLINKLYEASQAGVKIELIIRSICCLRPGLAGLSENIRVRSIVGRFLEHTRVYYFYNNGDTRVYCSSADWMERNLFKRVEVCLPIENTGLKKRIYQQGLENYLMDNQQSWLLQSDGSWCRNISTEDQKPHNAQQMLLGDII
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: OXDA_RHOTO
Sequence: MHSQKRVVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPRQAKWEESTFKKWVELVPTGHAMWLKGTRRFAQNEDGLLGHWYKDITPNYRPLPSSECPPGAIGVTYDTLSVHAPKYCQYLARELQKLGATFERRTVTSLEQAFDGADLVVNATGLGAKSIAGIDDQAAEPIRGQTVLVKSPCKRCTMDSSDPASPAYIIPRPGGEVICGGTYGVGDWDLSVNPETVQRILKHCLRLDPTISSDGTIEGIEVLRHNVGLRPARRGGPRVEAERIVLPLDRTKSPLSLGRGSARAAKEKEVTLVHAYGFSSAGYQQSWGAAEDVAQLVDEAFQRYHGAARESKL
What is the function of this protein?
This enzyme can effectively convert cephalosporin C into 7-beta-(5-carboxy-5-oxopentanamido)-cephalosporinic acid.
What are the official names of this protein?
D-amino-acid oxidase, DAAO, DAMOX, DAO.
What is the protein family that this protein belongs to?
Belongs to the DAMOX/DASOX family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RBE32_LITRU
Sequence: VGFFT
What is the function of this protein?
Shows neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Rubellidin-3.2.
What are the subcellular locations of this protein?
Secreted.
Protein: UB2R2_MOUSE
Sequence: MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination.  May be involved in degradation of katenin.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 R2, E2 ubiquitin-conjugating enzyme R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: DNAK_RHOP5
Sequence: MGKVIGIDLGTTNSCVAVMDGKTPKVIENAEGMRTTPSIVAFSDDGERLVGQPAKRQAVTNPERTFFAVKRLIGRRYDDPMVEKDKKLVPYKIVKASNGDAWVEADANTYSPSQVSAFILQKMKETAEAHLGAKVDQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKAKAGVIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDMRLVSYLADEFQKEQGINLRNDKLALQRLKEAAEKAKIELSSTTQTEINLPFITADQTGPKHLTMKLTRAKFEALVDDLVQKTIEPCRKALKDAGLTAGEIGEVVLVGGMTRMPKVQEVVKQLFGKEPHKGVNPDEVVAIGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRIIDRNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKVLGQFDLMGIPPSPRGMPQIEVTFDIDANGIVNVSARDKATGKEQQIRIQASGGLSEADIDKMVKDAEINAAEDKKRREAVDAKNHADALVHSTEKALAEHGAKVEEPERRAIEDALSDLREALKGDDAEAIKTKTNTLAQASMKLGEAMYKQQAEADAAKDAAKDDVVDAEFTEVDDDKNTKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.