PharMolix/UniProtQA huggingface dataset:
Protein: BUD32_ASPOR
Sequence: MSQDPYTPPPLPKPFTNTTPPPTLLTQGAEAHLYKTIHLNTNTPAALKIRPSKPYRHPILDRRLTRQRILQEARCLVKLVREGVNVPAVLALDWEGQGGENGNGGAWLLMEWIEGLVVRVVFERWEAFIKASGGSLGEKELRREEEKVRGLMRGIGGVVGGLHKAGVIHGDLTTSNLILRTGDVDIKDGESPAMVGDVVLIDFGLAGQSSSEEDRAVDLYVLERAFGSTHPQAEKFFEEVLEGYKDSYKGAAVTLKRLQDVRMRGRKRSMIG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit bud32, Atypical serine/threonine protein kinase bud32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: CEDA_ECOUT
Sequence: MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.
Protein: DAPA_PROMS
Sequence: MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESPTLSWAEQHDLFIAVKGSLDASCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNKPPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTVKKLMDFSNILSIKAASGRIEEVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSNALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_THEPX
Sequence: MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGPPGLGKTTLATVISNEMGVGIKITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTRAALMTSPLRDRFGVINRLDYYSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYIDFKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEPYLLQIGFLNRTPRGRVVTKLAYDYLKYPYIEQGRIEGV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TIM22_XENTR
Sequence: MGGSVSPPGTGEGTLQYSLIMEHLVGDKRRPKEVIPGGLGGIPTPIKSEEQKMMERVMESCGFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGLKAGALGCGGFAAFSAVIDYYLR
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1363_STAAM
Sequence: MPIVNVKLLEGRSDEQLKNLVSEVTDAVEKTTGANRQAIHVVIEEMKPNHYGVAGVRKSDQ
What are the official names of this protein?
Probable tautomerase SAV1363.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: DF154_ARATH
Sequence: MAKISYSYFLVLMLVVSVFSVVEKAKGDGSCTIIIDPKAPSCDIIQCRLSCITDYNGLAECIASRIGSPPNCVCTYDC
What are the official names of this protein?
Putative defensin-like protein 154, Putative low-molecular-weight cysteine-rich protein 35, Protein LCR35.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CX6B1_MACMU
Sequence: MAEEDIETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTTKGGNVSVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI
What is the function of this protein?
Connects the two COX monomers into the physiological dimeric form.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: PHS_MYCVP
Sequence: MAVLTDEQVDAALPDLNGWERADGALRRSVKFSAFLDGIDAVRRVAEHAEAKDHHPDIDIRWRTVTFALVTHSEGGITDKDVQMARDIDGILG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MERR_SHIFL
Sequence: MENNLENLTIGVFAKAAGVNVETIRFYQRKGLLREPDKPYGSIRRYGEADVVRVKFVKSAQRLGFSLDEIAELLRLDDGTHCEEASSLAEHKLKDVREKMADLARMETVLSELVCACHARKGNVSCPLIASLQGEAGLARSAMP
What is the function of this protein?
Mediates the mercuric-dependent induction of mercury resistance operon.  In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.
What are the official names of this protein?
Mercuric resistance operon regulatory protein.
Protein: RNAS8_HUMAN
Sequence: MAPARAGCCPLLLLLLGLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINKYTERCKDLNTFLHEPFSSVAITCQTPNIACKNSCKNCHQSHGPMSLTMGELTSGKYPNCRYKEKHLNTPYIVACDPPQQGDPGYPLVPVHLDKVV
What is the function of this protein?
Has a low ribonuclease activity.
What are the official names of this protein?
Ribonuclease 8, RNase 8.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLOA2_RHOBA
Sequence: MRRPMIASLLLDTLPLAQMPKVTTALLIGALVIFAGIVVVLFIFTSYFGLWIQSVLTGSKISFGNLIGMTFRKVNTRAIVRSKIMATQAGLDDPELTVGALEAHYLAGGNVQQVIRALIAAKKAKTISLTFREATAIDLAGRDVLESVQTSVYPKVIDCPPRGSAKPSLDAVAKDGIQLKVRARVTVRANLQQLIGGATEETIIARVGEGIVSAIGSADDHKAVLENPDVISKAVLVKKLDSQTAFEIVSIDIADIDVGANIGARLQADQAEADTAVARANAEGRRAAAVAEEQEMQAEIAKSQAQVVEAQSDVPRAMAEAFRSGKLLVMDYYRLQNVSADTEMRRALAGHSHDPDTPEETH
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA 2.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: PDIP2_MOUSE
Sequence: MAGCVARRALAVGSRWWSRSLATTRGSRPLCAVGGAGGLPPVATATTRRHLSSRNRAEGKVLETVGVFEVPKQNGKYETGQLFLHSVFGYRGVVLFPWQARLYDRDVASATPEKAENPAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
What is the function of this protein?
Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites.  May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1).
What are the official names of this protein?
Polymerase delta-interacting protein 2.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Note=Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus.
Protein: PROA_LEPBA
Sequence: MTFEATEYAKSIATKAKEASRALKSLTTLQKNSVLKRVETLLLENETAIIKENQIDLQNGIQKGLSSAMMDRLLLDSKRIQSMAKSIEEIRNLPDPVGEVVRGTILPNGLELLTKRVPIGVVMTIFESRPNVIVDIASLSFKSGNACILRGGSEAYHSNLILSSLFHQAIGESNLPSVTKDVVSFVENTDREAMVPFFQLDDLIDVIVPRGGEALIRFVSENSKIPVIKHDKGVTNLYLSNKAKEDIVLPILINSKVQRPGVCNALENLFIHKDYPHIQTLLSDLQKAGVQVLGDQSTQSIFPNLPLATEADFYTEFLDTRLSVKIVKSVEDAMQNIQNYSSGHTECILSEDESEIQTFRQGLDSAAIFVNCSTRFHDGGEFGLGAEVGISTGKLHVRGPMGLIHLTTTTTYVTGKGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_ECO27
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPTTLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BOR1_ARATH
Sequence: MEETFVPFEGIKNDLKGRLMCYKQDWTGGFKAGFRILAPTTYIFFASAIPVISFGEQLERSTDGVLTAVQTLASTAICGMIHSIIGGQPLLILGVAEPTVIMYTFMFNFAKARPELGRDLFLAWSGWVCVWTALMLFVLAICGACSIINRFTRVAGELFGLLIAMLFMQQAIKGLVDEFRIPERENQKLKEFLPSWRFANGMFALVLSFGLLLTGLRSRKARSWRYGTGWLRSLIADYGVPLMVLVWTGVSYIPAGDVPKGIPRRLFSPNPWSPGAYGNWTVVKEMLDVPIVYIIGAFIPASMIAVLYYFDHSVASQLAQQKEFNLRKPSSYHYDLLLLGFLTLMCGLLGVPPSNGVIPQSPMHTKSLATLKYQLLRNRLVATARRSIKTNASLGQLYDNMQEAYHHMQTPLVYQQPQGLKELKESTIQATTFTGNLNAPVDETLFDIEKEIDDLLPVEVKEQRVSNLLQSTMVGGCVAAMPILKMIPTSVLWGYFAFMAIESLPGNQFWERILLLFTAPSRRFKVLEDYHATFVETVPFKTIAMFTLFQTTYLLICFGLTWIPIAGVMFPLMIMFLIPVRQYLLPRFFKGAHLQDLDAAEYEEAPALPFNLAAETEIGSTTSYPGDLEILDEVMTRSRGEFRHTSSPKVTSSSSTPVNNRSLSQVFSPRVSGIRLGQMSPRVVGNSPKPASCGRSPLNQSSSN
What is the function of this protein?
Efflux-type boron (B) transporter for xylem loading, responsive of boron translocation from roots to shoots under boron limitation (PubMed:16805739, PubMed:9390427, PubMed:12447444, PubMed:27449211).  Boron is essential for maintaining the integrity of plants cell walls (PubMed:16805739, PubMed:9390427).
What are the official names of this protein?
Boron transporter 1.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Transferred from the plasma membrane via the endosomes to the vacuole under high-concentration of boron in a DRP1A- dependent manner (PubMed:16103374, PubMed:27449211, PubMed:20194745). Localized to the polar inner/stele-side domain of the plasma membrane under low-boron conditions, this polar localization is established after cell division (PubMed:27449211). Co-localizes with DRP1A in the cell plate and the plasma membrane (PubMed:27449211). Under boron excess, BOR1 is transferred from the plasma membrane via the endosomes to the vacuole for degradation in a DRP1A-dependent manner (PubMed:16103374, PubMed:27449211, PubMed:20194745).
Protein: STAT3_CHICK
Sequence: MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAANKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQATHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRGIVSELAGLLSAMEYVQKMLADEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGITFTWVEKDISGKTQIQSVEPYTKQQLNSMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRSESQEHSEATDSGSAAPYLKTKFICVTPTSFSNTIDLPMSPRTLDSLMQFGNSSEGAEANAGGQFESLTFDMELTQECASSPM
What is the function of this protein?
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.
What are the official names of this protein?
Signal transducer and activator of transcription 3.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. Constitutive nuclear presence is independent of tyrosine phosphorylation (By similarity).
Protein: MAS_HUMAN
Sequence: MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV
What is the function of this protein?
Receptor for angiotensin 1-7 (By similarity).  Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels.  Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade.  The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
What are the official names of this protein?
Proto-oncogene Mas.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: ZAPD_CUPTR
Sequence: MILYEYPFNERIRTLLRLEDLFDRLEYFLGQDHAQQHHVALTTLFEIIDVAGRADLKTDLIKELERQRQALAPLRANPQIDQDALDSVIGEIEQGIAMLNQTVGKAGQLLTDNEWLTSIRSRAIIPGGTCEFDLPAYYAWQHRPAEDRRADILKWARPLVSLRMGTTIVLRLLREAGQSGKVIATGGSYQQMLSGRSYQLMQVYLDDSLLAFIPEMSANKYMLWVRFTQQDGDLRPRSVDADIPFLLKLCNF
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: H32_TETNI
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FOLD_XYLFA
Sequence: MIVSMLAATDLARILDGRRIADDLLDALKTRVDARVAAGKLPPTLAVVLVGSDPASVVYVRNKRRAAEKVGIKAYDFDLPEATTEAELAALIDRLNADPKIHGILIQLPLPGIPDAHRLIQRVDPRKDVDGFHPQNVGHLALREFGLRPCTPRGIVTLLGHTDRPVRGRNATIVGVSNHVGRPMGLELLMAGCTVTSCHKFTPPQMLEAAVRQADILIVAVGRPGVIPGEWVKPGAVVIDVGINRLDDGRLVGDVGFESAVKRASWITPVPGGVGPMTVATLMQNTLEAAEAADC
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RK23_EUCGG
Sequence: MDGIKYAVFTDKSIRLLGKNQYTFNVESGSTRTEIKHWVELFFGVKVKAMNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAA_PROMS
Sequence: MSRDLPNVIILIGPTASGKTELAIEIAEYFKTHIHNIDSRQIYKSMDIGTAKPSKNQQKKIKHFLIDIEEPIHPINVKQFQGIAQKSIKSEIKQNNLPFLVGGSGLYMNSITKGFFVPDVPPQNDLRKQLEELGQKKCWDLLKNCDPLSTKKINFADHIRTIRALEVFYVTGKPLSTLKVQRAPDWRILELGLDRDNLKERILQRTKNMFSAGIIEETNYLISKYGFDLPILETIGYREAKDVLKNHSTIDKAIELTTTKTIQYAKRQKTWFRNKNNPLWLDNKNLLKDAIIKIESFLS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: VWA2_HUMAN
Sequence: MPPFLLLEAVCVFLFSRVPPSLPLQEVHVSKETIGKISAASKMMWCSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFSTQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNASVPQILIIVTDGKSQGDVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSSSAICSSATPDCRVEAHPCEHRTLEMVREFAGNAPCWRGSRRTLAVLAAHCPFYSWKRVFLTHPATCYRTTCPGPCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCALKLSLECRVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPRRVVVLLTESHSEDEVAGPARHARARELLLLGVGSEAVRAELEEITGSPKHVMVYSDPQDLFNQIPELQGKLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHVAAYADLRYHQDVLIEWLCGEAKQPVNLCKPSPCMNEGSCVLQNGSYRCKCRDGWEGPHCENRFLRRP
What are the official names of this protein?
von Willebrand factor A domain-containing protein 2, A domain-containing protein similar to matrilin and collagen, AMACO, Colon cancer secreted protein 2, CCSP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_RICPU
Sequence: MTHSPLAQFDIKKLIDIKMFGFDVSFTNSSIYMLLASILALTYFYLAFYNRKLVPSRLQVSAEIVYNLVADMLNQNIGVKGRKFIPLVFSLFIFILFCNLLGMTPYSFTATSHIIVTFTLAILVFLIVTIVGFVKHGLRFLTLFLPHGTPLWLAPLIIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIAGFTVSLMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GHR_BOVIN
Sequence: MDLWQLLLTLAVAGSSDAFSGSEATPAFLVRASQSLQILYPVLETNSSGNPKFTKCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYFNSSYTSVWTPYCIKLTSNGGIVDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLMVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDFQFPWFLIIIFGILGLAVTLYLLIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDNAYFCEVDAKKYIALAPHVEAESHVEPSFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALPLPDKEFLSSCGYVSTDQLNKIMP
What is the function of this protein?
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
What are the official names of this protein?
Growth hormone receptor, GH receptor, Somatotropin receptor.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway. SUBCELLULAR LOCATION: [Growth hormone-binding protein]: Secreted. Note=Complexed to a substantial fraction of circulating GH.
Protein: ODBB_RAT
Sequence: MAAVAARAGGLLRLGAAGAERRRRGLRCAALVQGFLQPAVDDASQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDE1B, BCKDH E1-beta.
What are the subcellular locations of this protein?
Mitochondrion matrix.