PharMolix/UniProtQA huggingface dataset:
Protein: RLUB_VIBVU
Sequence: MNEKLQKVLARAGHGSRRELEALIKSGRVSVNGIVAKLGERLEDEQAVVRIDGHVVSVKAQEEVICRVLAYYKPEGELCTRHDPEGRRTVFDRLPKIRGSRWISVGRLDANTSGLLLFTTDGELANRLMHPSRQVEREYLVRVFGEVNEHKVRNLVNGVELDDGLARFEDVVYTGGEGMNHTFYVVINEGRNREVRRLWESQDCTVSRLKRVRYGDIYLDKKLPRGGWMELELKDVNYLRELVELRPEKETMIELNNSSRKRDRARSQKIRRAVKRHEERVSTPKGRSNNAARRKPSKADGQTNKTNSRNQAGSRSKPQR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: MURA_BRUC2
Sequence: MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRTIHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARNGLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRIIPDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQFMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIVNRVYHLDRGFERLEEKLSRCGADVKRISG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUXF_ARATH
Sequence: MATIPVNPKPFLNNLTGKTVIVKLKWGMEYKGFLASVDSYMNLQLGNTEEYIDGQLTGNLGEILIRCNNVLYVRGVPEDEELEDADQD
What is the function of this protein?
Probable common Sm protein, is found in U1 and U2 snRNPs and may be part of the spliceosome.
What are the official names of this protein?
Probable small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: O1VA_CONGR
Sequence: MKLTCVLIITVLFLTACQLTTAVTYSRGEHKHRALMSTGTNYRLLKTCRGSGRYCRSPYDCRRRYCRRISDACV
What is the function of this protein?
The activity of this natural homodimer has not been tested due to low abundance (PubMed:28598389).  The synthetic linear peptide has been refolded, giving 4 different monomeric isomers (m1 to m4) with 2 disulfide bonds each (PubMed:28598389).  All isomers potently inhibit rat alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE and human alpha-9-alpha-10/CHRNA9-CHRNA10 nicotinic acetylcholine receptors (nAChR) (PubMed:28598389).  In addition, they show a modest inhibition at human alpha-3-beta-2/CHRNA3-CHRNB2, alpha-3-beta-4/CHRNA3-CHRNB4, alpha-7/CHRNA7, and alpha-4-beta-4/CHRNA4-CHRNB4 (PubMed:28598389).  The synthetic monomer peptide without disulfide bonds shows a potent activity on alpha-9-alpha-10/CHRNA9 and CHRNA10 (IC(50)=16. 2 nM) (PubMed:28598389).  This linear peptide does not act as a competitive antagonist, or as a channel pore blocker of nAChR (PubMed:28598389).
What are the official names of this protein?
O-conotoxin GeXXXIA, O-conotoxin GeXXVIIA, O-GeXXVIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAD_PSEAB
Sequence: MRVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVYGGVVPELASRDHVKRMLPLIRQVLDESGCTPADIDAIAYTAGPGLVGALLVGASCAQAVAFAWGVPAVGVHHMEGHLLAPMLEEQPPRFPFVALLVSGGHTQLVRVDGIGRYQLLGESVDDAAGEAFDKTAKLIGLGYPGGPEIARLAERGTPGRFVFPRPMTDRPGLDFSFSGLKTFTLNTWQRCVEAGDDSEQTRCDIALAFQTAVVETLLIKCRRALKQTGLKNLVIAGGVSANQALRSGLEKMLGEMKGQVFYARPRFCTDNGAMIAYAGCQRLLAGQHDGPAISVQPRWPMESLPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CHRSD
Sequence: MALTQEDIINAVAEMSVMEVAELISAMEEKFGVSAAAAVVAGPGAGGEGEAAEEQTEFDLVLTGAGDKKVNVIKVVREITGLGLKEAKGAVDGVPATLKEGMSKEDAEAAKTKLEEAGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: IDI2_IGNH4
Sequence: METSNRKLDHLRITLLEDVEAGDTWLDFVKVPHRAVPELNLEEVVTEIEVFGKKLSAPLIVTGMTGGNEHAAKINAVIAEVVEELGLGMGVGSQRAAVERPELEWTFRIARERAPNALLIANLGAPQLLKGYGLEEIKKAIDMIDADAIAIHLNAAQESFQPEGDVDYKGLLNKLSELVDKVEKPIIIKETGAGLDYESVKALRELGIKAFDVSGSGGTSWVRVEMYRAREKGDEVLATVADWMSSWGIPTAASIMEARAAAPDALVIASGGIRDGLHAVKSLALGADLVGVALPALKAAYEGKEELKKFLKSMMLSIKIGLFLTGSPAPEHIKGKAIVLGPLKEWALERGIYEEWLRAR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ACIBC
Sequence: MISLSDLRKFKAEGRKFSCLTCYDASMAKAMELAEIDTILIGDSLGMAIQGRDSTLPVTVEDMAYHTAAVRRGNQHALIMTDLPFMSYATLNDALQNAKTVMQAGAQMIKIEGGAWLSETVQVLTRNGVPVCVHLGLTPQSVHVFGGYKLQARTREAADQLIADCTAVVEAGAAVLLLECVPAQLGQEIAELFPNTPVIGIGAGNATDGQVLVVQDMLGLTFGRVARFVRNFMKEQSGETAILDAFKAFHAAVQDQSFPAKEHTFQVEL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_DECAR
Sequence: MQIYIVGGAVRDELLGRPNADCDYVVVGATPETMLAQGFRPVGKDFPVFLHPNTHDEYALARTERKTGHGYHGFIFHAAADVTLEEDLARRDLTINAMAKAADGTLVDPFNGQQDLASKTLRHVGPAFAEDPVRILRIARFAARFSDFSVAPETLALMRSMVACGEVDHLVAERVWQELAKGLMEQKPSRMFEVLRDCGALARLLPEVDKLFGVPQRADYHPEIDTGIHTMMVIDQSARRTFTLPVRFAALTHDLGKAETPADILPRHIGHEERSVRLTEQLCARLRVPNDCRDLALLTARYHGNIHRAADLKASTIVTLFEKTDALRRPERFRQLLDACLCDFTGRLGWENRPYDSPQYLLGALAAVASLNAGEIAVACADKTKIPERIHAARVHAIKQLLDNPGEQPEQQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RL10_CHLPM
Sequence: MKREKKEQVVQSVTEKVSRSQGIYLTEFQGLSVSRMSELRNEFRKAGVEYRVVKNTLVKKALSDLAGADRLAGALKNTTGVAFGYDDPIAPARVIKKFSKDNESLKFKMAAIDGVVFEADQLGVLSEMLTKTENIGRAAGIINNVIASVPMVMNAVMRDLVSVVDQVGKQKQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: FA9_CANLF
Sequence: MAEASGLVTVCLLGYLLSAECAVFLDRENATKILSRPKRYNSGKLEEFVRGNLERECIEEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNDGVCKDDINSYECWCRAGFEGKNCELDVTCNIKNGRCKQFCKLGPDNKVVCSCTTGYQLAEDQRSCEPAVPFPCGRVSVPHISMTRTRAETLFSNMDYENSTEVEKILDNVTQPLNDFTRVVGGKDAKPGQFPWQVLLNGKVDAFCGGSIINEKWVVTAAHCIEPDVKITIVAGEHNTEKREHTEQKRNVIRTILHHSYNATINKYNHDIALLELDEPLTLNSYVTPICIADREYSNIFLKFGSGYVSGWGRVFNKGRSASILQYLKVPLVDRATCLRSTKFTIYNNMFCAGFHEGGKDSCQGDSGGPHVTEVEGISFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: INT10_DANRE
Sequence: MSAQGDCEFLVKRARELVPQDPYAAKAWLITARTLYPTDFNIQYEMYSIERNAERTSSAGRLLYDIFVNFPDQPVVWREISAITAALRNDSQDKHAQFLKGVFETLPGQVQCKMLLKATEQCFNTLEKAEMLLLLLKRFPESVVQHGVSLGESLLEAESVEDLETPVNCFRKLFVCDVLPLILNNPEMCLPVSLLYKYLHKAAEFYICYVTREPSADGQMQGSQEVGGLNSPGRGRGQRSVIDGLSDKASVVTEPWDRLLEMVGVVGSLCDWQGEKGSRSYAELLQRVSDLCRFLSAADADGFSRCCSQIVSCCTLVLFHCAFHYVSAVQPSLFQGHSSLSSGPWVLLEDLSSVYADVEVERKHTHKKRKLADGREKTMSSDDEDVLAKGRGRHIVVSKSEMLNWAETLDHFRTARESWDLLHSHPSLEAEFAKICSAWKTEMWLWFRIFLTDMIIYQGQYRKALSSLALMSSLQLQQNQNQNQNSLQTGSSSSLENHRAVIQQASCHYALGEYRLACEKLLEAVGGLLPQNQEFVKSSDEQRKPRSKTRRGNDLRLVPCTSKSILPFCLQLMLACFKLRAFTDNRDDLALGHVIVLLQFDWPQGESLFLKAVDKICQQGSFQYENFFNYVTNIDMLEEFAYLRTTEGGRVQLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLLMVLHRFCINEKIILIQSLP
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 10, Int10.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARND_ECOK1
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQAHSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGTPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRIQRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVVRGNIAGREGWLGCQQIAGSH
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: DNAK_HELPG
Sequence: MGKVIGIDLGTTNSAMAVYEGNEAKIIANKEGKNTTPSIVAFTDKGEILVGESAKRQAVTNPEKTIYSIKRIMGLMFNEDKAKEAEKRLPYKIVDRNGACAIEISGKVYTPQEISAKILMKLKEDAESYLGESVTEAVITVPAYFNDSQRKATKEAGTIAGLNVLRIINEPTSAALAYGLDKKESEKIMVYDLGGGTFDVTVLETGDNVVEVLATGGDAFLGGDDFDNRVIDFLSAEFKSETGIEIKNDVMALQRLKEAAENAKKELSSAMETEINLPFITADATGPKHLVKKLTRAKFESLTEDLMEETISKIESVIKDAGLTKNEISEVVMVGGSTRIPKVQERVKAFINKDLNKSVNPDEVVAVGASIQGGVLKGDVKDVLLLDVTPLSLGIETLGGVMTKVIDRGTTIPAKKSQVFSTAEDNQPAVSIMVLQGERELARDNKSLGKFDLQGIAPAPRGVPQIEVTFDIDANGILTVSAQDKNTGKSQEIKISGSSGLSDSEIEKMVKDAELHKEEDARKKEVIEARNHADSLAHQTQKSLDEHKTNLNENDANEIQNAINALKDCIKNDNATKAELEDKTKLLAQAAQKLGEAMANKNNAEQPKKKDDDVIDAEVE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: BDNF_URSTH
Sequence: MTILFLTMVISYFGCMKAAPMKEANVRGQGSLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPSEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Important signaling molecule that activates signaling cascades downstream of NTRK2.  Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2.  Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).  Binding to NGFR and SORCS2 promotes neuronal apoptosis.  Promotes neuronal growth cone collapse.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [BDNF precursor form]: Secreted. Note=A proportion of BDNF is secreted as immature precursor (proBDNF).
Protein: YWLB_BACSU
Sequence: MFYQLRVAREKDGDVLEAFLKQAKTSYEGVKEGFTQFLMLEDSEKNIAGCLGIEKISCDQGLLRSLVISDKLHQGHIVTLFQSMEVLCEKHQIKTVYLVANQHSSADFLTAMGFERAESVPEELFSSDHFCESRQTEGAVLMKKASG
What are the official names of this protein?
Uncharacterized protein YwlB.
Protein: KCNKF_HUMAN
Sequence: MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCARDNLGFSPPSSPGVVRGGQAPRLGARWKSI
What is the function of this protein?
Probable potassium channel subunit.  No channel activity observed in heterologous systems.  May need to associate with another protein to form a functional channel.
What are the official names of this protein?
Potassium channel subfamily K member 15, Acid-sensitive potassium channel protein TASK-5, TWIK-related acid-sensitive K(+) channel 5, Two pore potassium channel KT3.3, Two pore K(+) channel KT3.3.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FDL17_ARATH
Sequence: MDHEDVTRRAVEKKNKLASSLIHAPFAICGLCWAFVYQKLIYKQTYTDTHARNYKVPARFQLPDPLLTQILNHLPTEEAVKTSVLSTRWRTLWLWVHNLELSFSKFSSFNAFLSFGNWFFDSDRVSCIESLKLSLDGNDASYLKPWIDAFVKRKIQRLHVRLTQGCEMPLSLYRLVSSCPVLEELKIDVVWMDGRVYRVHSRSLKSFILTDLESDAKFDISLRFHKWVFNEAKTSTIHMFLAWISRVRDMTICAQTFKLIHHYSESVQLPQFGYMSSLYITLNASDLKWFPIFLRSIPNLKSLILVMERTGSSHQLSPKAIKRVSISSVPECLLSSLEFVEFKAPICGLAPEMMLVWYFLENSPTLKKLTLRLKSHSTKDDFVKKLLKIPRCSTECEVIFL
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At3g23955.
Protein: RRF_RICCK
Sequence: MDTETLKKNLQEKMEKALKVLDHELKGLRTGRASVNLLDSVIVEAYGSKIPLSQVASISTPDARTINVQVWDKSMVSLVEKGITIANLGLTPATDGQLIRLPIPILTEERRKELVKLAHKYGEDTKISLRNIRRDGNEELKKLEKNNILTKDEHHSLSEQVQKLTNDYSNKVDSAIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_PSINU
Sequence: MAKKVKGARVTIHLECIDCNNQQDSGRKLASFSRYTTQKNRYNTPTRLELKKFCPSCSKHTIHIE
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KHDC4_DANRE
Sequence: MSFGVPHSGGSRRSKWDQAGPDADAGSAPTGALDAAAAVAAKINAMLVAKGKLKPSQISSAAPVDKAAGAGGNKLKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRVSGAAVSTRGRFMTVEEKSKALPSDRPLYLHVQGQTRDLVDKAVNRIKEIITNGVVKAATNSTYSGATVTVYQQSGPSVPTIPSAPHKPHYPGGMHYVQDKVFVGLDQALQGFNVKERVEGPSCSFLQHIQAETGAKVFLRGKGSGCLEPASGREAFEPMYIYISHPKPEGLASAKTLCENLLQTVHAEYSRYLNQMSSMMPTQGFIHPPVVNGLPPQPPYYSPAGFQPSYPAPVPPPPPPIAPQYPVAPVAPAPVPPPNAQYPITPVPAHVPTQTLLPAAFPPTAPVPPKLTAPPNPPQKRRFTEEVDEMDRGLLGYQHGPIHMTNLGAGMPVGSSETSGPPSAASSVPVRERDSSRQLMPPPCAPALLKPLRPLKADESPSAPSLLEPQVKRMRTGLVAYAGDSSDEEEDHGPSRAAVTAAGNPGAGWNPYRCPPSPPHRPKTQTAPQPTQQNMPFWMAP
What is the function of this protein?
RNA-binding protein involved in pre-mRNA splicing.  Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome.  Involved in regulating splice site selection.  Binds preferentially RNA with A/C rich sequences and poly-C stretches.
What are the official names of this protein?
KH homology domain-containing protein 4, Brings lots of money 7, Pre-mRNA splicing factor protein khdc4.
What is the protein family that this protein belongs to?
Belongs to the KHDC4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: METXS_BREDA
Sequence: MTLALISTETTEEPSCKASVAAPAPKGGAQIGVKAARRPSELLQRDGAHDVAVAIPDDFELDFGGTLTQKRVIGRLHGKANAPLIVVAGGISADRYVHRTETKGLGWWSGAVGVRAPIDLTRFRVLAFDFAPEFGEDVKDAKTPLTITTQDQARLLALLLDHLGVEKVAAFIGCSYGGMIALAFGELFPDWAEQLVVVSAAHRPHPLATAWRGIQRRILQLGLETGRIDQAVGLARELAMTTYRTQEEFGDRFDSEAPSHAGQAYPVCDYLQARGRAYRDRTTPSRWLSLSDSIDRHRVEPEAITAPVTLIGFTTDRLCPIEDMRELADRLPNLWRFEQHASVYGHDAFLKEDKLVADILTSVLKDIDQ
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CAMJR
Sequence: MQIMLCAISNIASGNCSEDCKYCTQSAHVKTDIQKYRRKELSQIVLEAKMAKKNEALGFCLVTAGLGLDDEKLEYVCEAAKAVQKEAPNLLLIACNGMASVEQLKELKKAGIFSYNHNLESSKEFFPQICTTHTWESRFQTNLNAKEAGLMLCCGGIYGMGESEEDRLSFRKSLQELQPFSTPINFFIANENLKLQVPRLSVDEALKIVRDTKEALPQSVVMVAGGREVVLRERQYEIFQAGAGAIVIGDYLTTKGEEPSQDIIKLKEMGFTFASECH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KN7C_ORYSJ
Sequence: MGAIGGDELVQWDKMGAAEAVNGGCGGAGKMDRIQVLVRLRPLSEKEVARREPAEWECINDSTVMFRSTFPDRPTAPTAYTFDRVFHSDCSTKEVYEEGVKEVALSVVSGINSSIFAYGQTSSGKTYTMTGVTEYTVADIYDYINKHEERAFVLKFSAIEIYNEVIRDLLSAENTPLRLWDDAEKGTYVENLTEVVLRDWNHLKGLISVCEAQRRTGETFLNEKSSRSHQILRLTVESSAREFLGKDKSTTLVASANFVDLAGSERASQALSAGTRLKEGCHINRSLLALGTVIRKLSMGSNAHIPYRDSKLTRILQPSLGGNARTAIICTLSPATSHIEQSRNTLLFGSCAKEVVTNAQVNVVMSDKALVKHLQKELARLESELRHPVQSSSLETLLKEKDNQIRKMEKEIKELKSQRDLAQSRLQDLLQSVGDHDLNRQVQGKHSVRSPPSVGMPPSVSRDDSSQVSHDDSDLYKEVRCIESNRTGGNDQLDLSAGESSSPQDSNMNSGLHGNDSNASVNSRHSRPSGEAPITLEEHLENIRRPFVSLAKDLGSSTRNSSNLRVIGRSRSCRSLTGSTMFDDMEMDDCTPLNRSLVEFPGRPVESHRRGSALHYDAETDTLSRAGSMSSEISTFKDAKTNGSVACDTEFTGIGEFVAELKEMAQVHYQKQLGDQNANGKSIGLDPIEGVSQSPSRWPLEFEKKQQEIIELWQACSISLVHRTYFFLLFKGEAADSIYMEVELRRLSFLRDTYSRGSTPSNAIVGSLSTSPVASAKKLQREREMLARQMQKRLSTEEREHTYTKWGVSLDSKRRKLQVARRLWTETKDLEHVRESASLVAKLIGLQEPGQVLKEMFGLSFAPQQQPTRRRSSNGWRYGIPSFA
What are the official names of this protein?
Kinesin-like protein KIN-7C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Protein: DKSA_BUCBP
Sequence: MQKEKNKKQSSLSILFMAGVQPYKNKKNEKYMNTKQIDHFKKILIAWKNQLRNDISQTRLNIQDKATNYPDPIDRAVQEEEFSFELRHRDRERKLIEKIEKTLKKVENKDFGYCESCGIEIGIKRLEARPTANLCIDCKTLSEIREKQILG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_YERPG
Sequence: METLASLYNEHLSTLQQRTRDVLERHQLDALLIHSGELQRLFLDDRDYPFKVNPQFKAWVPVTEVPNCWLWVDGVNTPKLWFYSPVDYWHSVEPLPDSFWTKNIDVQPLLNADDIAQQLPVQRERVAYIGYAQQRAQALGFSAENINPQPVLDYLHYYRSYKTDYELACMREAQKTAVVGHRAAYEAFQSGMSEFDINLAYLMATGHRDTDVPYDNIVALNEHSAVLHYTILQHQPPAEIRSFLIDAGAEYNGYAADLTRTYTADRDSDFAALISDLNTEQLALIDTIKSGERYTDYHVQMHQRIAKLLRTHNLVTGISEEAMVEQGITCPFLPHGLGHPLGLQVHDTAGFMQDDKGTNLNAPSKYPYLRCTRVLQPRMVLTIEPGLYFIDSLLAPWRIGEFSKHFNWDRIDALKPYGGIRIEDNIVIHDKRVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: TM233_HUMAN
Sequence: MSQYAPSPDFKRALDSSPEANTEDDKTEEDVPMPKNYLWLTIVSCFCPAYPINIVALVFSIMSLNSYNDGDYEGARRLGRNAKWVAIASIIIGLLIIGISCAVHFTRNA
What are the official names of this protein?
Transmembrane protein 233, Dispanin subfamily B member 2, DSPB2, Interferon-induced transmembrane domain-containing protein D2.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ECCB4_MYCTO
Sequence: MPSPATTWLHVSGYRFLLRRIECALLFGDVCAATGALRARTTSLALGCVLAIVAAMGCAFVALLRPQSALGQAPIVMGRESGALYVRVDDVWHPVLNLASARLIAATNANPQPVSESELGHTKRGPLLGIPGAPQLLDQPLAGAESAWAICDSDNGGSTTVVVGPAEDSSAQVLTAEQMILVATESGSPTYLLYGGRRAVVDLADPAVVWALRLQGRVPHVVAQSLLNAVPEAPRITAPRIRGGGRASVGLPGFLVGGVVRITRASGDEYYVVLEDGVQRIGQVAADLLRFGDSQGSVNVPTVAPDVIRVAPIVNTLPVSAFPDRPPTPVDGSPGRAVTTLCVTWTPAQPGAARVAFLAGSGPPVPLGGVPVTLAQADGRGPALDAVYLPPGRSAYVAARSLSGGGTGTRYLVTDTGVRFAIHDDDVAHDLGLPTAAIPAPWPVLATLPSGPELSRANASVARDTVAPGP
What is the function of this protein?
An ATPase (By similarity).
What are the official names of this protein?
ESX-4 secretion system ATPase EccB4, ESX conserved component B4, Type VII secretion system protein EccB4, T7SS protein EccB4.
What is the protein family that this protein belongs to?
Belongs to the EccB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.