PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_SULSY
Sequence: MVIFSTGFNYKTAPVEIREKLAITENNYGLILEKLNSIEDIYEICVISTCNRVELYGVSNDNIEKVKEEILRILSQYSTVPVNTLKDYLFFYTNKEAIRHIFRVSSSLDSMVIGEPQIVCQFKDSFTKAKEYKAVRHILTRLFDKALNVSKKIRTSTGISRRAVSISYAAVLLAKKIFGDLKDKNVLIIGAGEMAELAAKHLHSLNVKHIFVSNRTFEKAVELADKFSGSAIRFEKIQEFLPEADIIIVSTGAKEPILKKEDVKRAIKSRKDPLFIIDISVPRNVEESVNELEGVYLYNIDDLKQVVNSNLEERKIEAQRAEFIIDEEVEKFVKWLNALKVSPIISSVRDYADKLRQQQLEKLFKQMPYLNEKERETIDLAMRSLINKLLHRPTMYIKDKAAKEGNTEVVKIFEDMFSSKWDFRKKGKNLEEIEDIVREEQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: VEL_LACBS
Sequence: MFTTHPQGRSYRSSVPHHHLRQPEIQNSYDQHANNPPRQTRRRPLADMIGHPIHFLTGQFAGQTIRAELDEIQKADLGRKYARVDRRPLDPPPVVRLRYFDIREDDVDQERGTEIKNYDEIQTIGLMSTVDLFPVPNESWTSRSPTQTSFSSSSPTLSNGNENFMFSSPQTSSPTAAQSQASTPNSPSSNDIIHYVGNHAITESSKVTSSLVGATFVQPAIVDYEGKKTIIFVFSDLAVKIEGTFLLRYRVFDIYSRPRDREDLLVQAECYGGPFRVYSTKEFPGLQASTDLTKHLARWGVRLNIRETERKRRKKGEIGSPLDDPKSKRKRTSLGSEDDEASDED
What is the function of this protein?
Velvet-domain-containing protein that probably acts as a positive regulator of sexual development.
What are the official names of this protein?
Probable velvet family sexual development regulator LACBIDRAFT_317102.
What is the protein family that this protein belongs to?
Belongs to the velvet family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIUH_BACSU
Sequence: MGKLTTHILDLTCGKPAANVKIGLKRLGESIMKEVYTNNDGRVDVPLLAGEELMSGEYVMEFHAGDYFASKNMNAADQPFLTIVTVRFQLADPDAHYHIPLLLSPFGYQVYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase, HIU hydrolase, HIUHase, Transthyretin-related protein, TRP.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: POF12_SCHPO
Sequence: MTTDVKAKNPASIFSHETLLHVLNDLSAHDLAALERVSRSWNSIVRRSSVWHNLYLSEFGTKHLRRHGRIEKKRRNWKGLFRRQSNWKDGRCKKVESMLPQLLNSEKSVGEDRLGLTLTHQNNIYFCNDVQISKWSSVGNSLKCQAISSFRDETVKSGPAVMCLDNASLYIGLKDGNLLHVTVHETGFGNIENLATFSTKFVALSSHKNYICGLTNDNNLYILQHSHQAGTKLKVLGKYHVSSIEKQVAIHFQQSKEGYEVVHVVFNDYVLSGGWTVSLQEFVFNEYCVKSSRLALHDNKDIEYSQQPASAIFMYGSYILTSHPDNSLILQRLYSTNNELRIKFLGRLLGHVCGVQISKLFSCGRIVSVSKNCADICVWDLHDTNYQSIVSPLMLTCTNIHNKPVSDYEKECKVQDIGLYEDTILITLSDGRILKFLFNI
What are the official names of this protein?
F-box protein pof12.
Protein: THIG_SHEAM
Sequence: MLKIAETEFGSRLFTGTGKFASGKLMQEAIAASGSELVTLAMKRVDFKTGSDDILAPLLSRGVRLLPNTSGARNAKEAIFAAELAREMLGTEWLKLEIHPDPKYLMPDPMETFAAAKELVSQGFKVLPYVHADPVLCRRLEEIGCAAVMPLGSPIGSNQGLVSREFLKIIIEQASIPVVVDAGIGAPSHACEAMELGADAVLVNTAIASSADPVRMARAFALAVQIGREAYLAGLGSKSLHAHETSPLTGFLNTGLSTTGLVDSGMAEKLL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_CAMJ8
Sequence: MLLGVNIDHIAVLRQARMVNDPDLLEAAFIAAKHGDQITLHVREDRRHAQDFDLENIIKFCKSPINLECALNDEILNLALKLKPHRVTLVPEKREELTTEGGLCLNHTKLKQSIEKLQNANIEVSLFINPSLEDIEKSKNLKAQFIELHTGHYANLHNALFSNISHTAFALKELGQDKKNLQAQFEKELQNLELCAKKGTELGLKVAAGHGLNYKNVKPVVKIKEICELNIGQSIVARSVFTGLQNAILEMKELIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_CORGL
Sequence: MFGLSKVLRVGEGRAVKRLHKIADQVIALEDKFANLTDEELKAKTAEFKERIAGGEGLDEIFLEAFATAREAAWRVLGQKHYHVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEMMGRVHRYLGLEVGVILSDMRPDERREAYAADITYGTNNELGFDYLRDNMARSLSDLVQRGHNYAIVDEVDSILIDEARTPLIISGPVDGTSQFYNVFAQIVPRMTKDVHYEVDERKKTVGVKEEGVEYVEDQLGIDNLYAPEHSQLVSYLNNAIKAQELFTRDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKERVEIKNENQTLATVTLQNYFRLYTKLAGMTGTAETEAAELNQIYKLDVIAIPTNRPNQREDLTDLVYKTQEAKFAAVVDDIAERTEKGQPVLVGTVSVERSEYLSQLLTKRGIKHNVLNAKHHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPEILLDIKLRERGLDPFEDEESYQEAWDAELPAMKQRCEERGDKVREAGGLYVLGTERHESRRIDNQLRGRSARQGDPGSTRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDEVMNEQRKVIYSERREILESADISRYIQNMIEETVSAYVDGATANGYVEDWDLDKLWNALEALYDPSINWTDLVEGSEYGKPGELSAEDLRTALVNDAHAEYAKLEEAVSAIGGEAQIRNIERMVLMPVIDTKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNGMKDGIKEETVRQLFLLRKQFIKQDAEVAD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: GDB1_WHEAT
Sequence: MKTFLVFALIAVVATSAIAQMETSCISGLERPWQQQPLPPQQSFSQQPPFSQQQQQPLPQQPSFSQQQPPFSQQQPILSQQPPFSQQQQPVLPQQSPFSQQQQLVLPPQQQQQQLVQQQIPIVQPSVLQQLNPCKVFLQQQCSPVAMPQRLARSQMWQQSSCHVMQQQCCQQLQQIPEQSRYEAIRAIIYSIILQEQQQGFVQPQQQQPQQSGQGVSQSQQQSQQQLGQCSFQQPQQQLGQQPQQQQQQQVLQGTFLQPHQIAHLEAVTSIALRTLPTMCSVNVPLYSATTSVPFGVGTGVGAY
What is the function of this protein?
Gliadin is the major seed storage protein in wheat.
What are the official names of this protein?
Gamma-gliadin B-I.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: KSHA5_RHORH
Sequence: MSIDTARSGSDDDVEIREIQAAAAPTRFARGWHCLGLLRDFQDGKPHSIEAFGTKLVVFADSKGQLNVLDAYCRHMGGDLSRGEVKGDSIACPFHDWRWNGKGKCTDIPYARRVPPIAKTRAWTTLERNGQLYVWNDPQGNPPPEDVTIPEIAGYGTDEWTDWSWKSLRIKGSHCREIVDNVVDMAHFFYIHYSFPRYFKNVFEGHTATQYMHSTGREDVISGTNYDDPNAELRSEATYFGPSYMIDWLESDANGQTIETILINCHYPVSNNEFVLQYGAIVKKLPGVSDEIAAGMAEQFAEGVQLGFEQDVEIWKNKAPIDNPLLSEEDGPVYQLRRWYQQFYVDVEDITEDMTKRFEFEIDTTRAVASWQKEVAENLAKQAEGSTATP
What is the function of this protein?
Probably involved in the degradation of cholesterol (PubMed:21642460).  In vitro, catalyzes the introduction of a 9alpha-hydroxyl moiety into the ring B of 3-ketosteroid substrates such as 1,4-androstadiene-3,17-dione (ADD), 4-androstene-3,17-dione (AD), 4-androstene-17beta-ol-3-one (testosterone), 4-pregnene-3,20-dione (progesterone), 19-nor-4-androstene-3,17-dione, 1-(5alpha)-androstene-3,17-dione, 5alpha-androstane-3,17-dione, 5beta-androstane-3,17-dione, 5alpha-androstane-17beta-ol-3-one (stanolon), 11beta-hydrocortisone, 3-oxo-23,24-bisnorcholesta-4-en-22-oate (4-BNC), 23,24-bisnorcholesta-4-ene-22-oate, 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate (1,4-BNC) and 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oyl-coenzyme A thioester (1,4-BNC-CoA) (PubMed:21642460, PubMed:25049233).  KshA5 has the broadest substrate range without a clear substrate preference and is active with Delta-4, Delta-1,4, 5alpha-H and 5beta-H steroids, as well as with steroids having bulky aliphatic side chains and an isopropionyl side chain at C17.
What are the official names of this protein?
3-ketosteroid-9-alpha-monooxygenase, oxygenase component, 3-ketosteroid-9-alpha-hydroxylase, oxygenase component, KSH, Androsta-1,4-diene-3,17-dione 9-alpha-hydroxylase, Rieske-type oxygenase, RO.
Protein: RL28_BACCQ
Sequence: MARVCAITGRKARSGNSRSHAMNATKRKWGANLQKVRVRIDGKVQRVYVSARALKSGKIERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DCL1_CHAGB
Sequence: MNAEMREGSSALPQLQAHSPVADNIDLMDIDEPASNGSFEESPATPFDDDAFVNAGDTDQEDDDPDTKKWIVNDSRKPRKISEKKRADHAAFDVWIEENQQDLSKGLDKFIVDDDGKTFQSLIRDFENKRIITSPRDYQLELFERAKTQNTIAVLDTGSGKTLIAALLLRWTIQNELEDRSKRLPKRIAFFLVDKVALVFQQHAVLACNLDYPLEKFCGDMVEDVTQDFWHKTFDENMAIVCTAEILYQCLTHSYIRMDQVNLLVFDEAHHTKKNHPYARIIKDFYAEVKDLNKRLRISRAMTASPVDAQIDPKIARSPELEGLLHSQIATVADPTALHNSSTKLKREVTVEYGKCLPEFETGLNRALKDLVGEHRLFQKPFAFTATAASELGPWCADRYWQLFFRGEEVVKLEAKTEREILRKSAYSQEIAAQVNKVREAHRLVGQHEFASPSSDLLSSKVVILLRILRGEFRGVDHKRRCIVFVRQRNVASLLTDLLQQPEMRIPGLEPGILVGGGRPEASYDNAKVTYRDQVLTIIKFKKGELNCIFATSVAEEGLDIPDCNVIIRYDLNNTLIQYIQSRGRARQEGSIYIHMVESENEEHVKKVCQNQESEDALRKFCEALPADRKLTGNNFDMEYFLRKEKDQRQYTVPETGARLNYKQSLICLAAFVASLPHPPEVNLTAGYLVLSVPGGYQCEVTLPESSPIRSATGKVYASKAVAKCSAAYEMCLMLIKGKYLDQHLRPTFTKQLPAMRNARLAVSSKKKEQYKMRIKPELWSVLGEPTELFAMALTLADPTALARHSSPLLLLTRQPIPQIASFPLYFGKNRSSAVHCVPVPGRVELDDNQIQGLVAVTLAIFKDIFSKEYEATAAQLPYFLAPTLMQHGSDFTSVTDLSRIVDWGAVTFVRDNERVAYALDDEADEFFKNKYVADPYDGSRKFFLRGRRHDMKPTDMVPEGIVTPGHRAWRVSCKTHDILNYSLSAWSKSRAFLTPREDQPVVEAEVLPIRRNLLDDHIGDDDLEPKPCFIVLEPLRISPLPVDLVAMAYNFPAIMHRIDSNLVALEACKMLNLNVRPDLALEAFTKDSDNSGEHDAEQISFQSGMGNNYERLEFLGDCFLKMATTISIFTLIPDKAEFEYHVERMLLICNRNLFNNALEVKLEEHIRSMAFDRRSWYPEGLTLKKGKRKDLTRQHVLADKTIADVCEALIGAAYLTAQEQTPPNFDLAIRAVTVMVKDKNHTMTSYSDYYAAYSPPAWQTAPCNSTQLDMAARFEARMGYAFTHPRLLRSAFQHPTYPSVYEKLPSYQRLEFLGDALLDMASVEFLFHRFPGADPQWLTEHKMAMVSNQFLGCLAVYLGFHRAISYCASAIQKEITEYVTEIEDALQSARDDASKTPCNRHATTPSPGDLPAESFARDFWVRCSRPPKCLPDVVEAYVGAVFVDSRYDFARVRAFFADHVRPFFEDMRLYDAFANKHPVTFLAGIMQGRMRCAEWRLLVKDLPPVVGAGAGTELETPQVVCAVRVHGLTLAHAVAASGRYGKIAAAKKAIQVLEGMDAEAFRKAYGCACVLGEEEQQAAQTIATELEVFPAFSASGLEVAHHGSAV
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: RR8_SOLLC
Sequence: MGRDTIAEIITSIRNADMDRKRVVRIASTNITENIVQILLREGFIENVRKHRENNKYFLVLTLRHRRNRKRPYRNILNLKRISRPGLRIYSNYQRIPRILGGMGIVILSTSRGIMTDREARLEGIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABH_ACIET
Sequence: MTRYSRITGTGSYLPPHRVTNDDLVAQLAQQGIETSDEWIVERTGIRARHFADRDVTSSDLALEASRRALEAAGCQAQDLDLIIVATSTPDMVFPSTACILQNKLGANGCPAFDVQAVCSGFVYALTVADAMIRSGGARRALVVGSEVFSRILDFNDRTTCVLFGDGAGAVVLEASEAPGILASDLHADGSHVGILCVPGNVYGGQILGDPLLKMDGQAVFKLAVGVLEKAARATLDKAGMTDADIDWLIPHQANIRIMQSTARKLKLSMDKVVVTVDQHGNTSAASIPLALDHGVRNGQVQPGQTVLLEGVGGGFTWGAVLLKM
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_VIBC3
Sequence: MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDIRTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLGIERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQQTVHALAALNSVLH
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIF_HV1U4
Sequence: MENRWQVMIVWQVDRMKIRTWNSLVKHHMYVSKKAQGWFYRHHYESRHSRVSSEVHIPLGEARLVVRTYWGLHTGEKDWHLGHGVSIEWRLKRYSTQVDPDLADHLIHLHYFDCFSESAIRRAILGQIVRPRCEYQAGHNKVGSLQYLALKALVTPTRAKPPLPSVKKLTEDRWNKPQKTRGHRGSRTLNRH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: TRMD_BORT9
Sequence: MKITILSLFPSIITPFFENSIMKKVISKGIISCEVISIRNFSDDKHKRCDDIPYGGGAGMVLKAQPISAALDYVNARSKTTIFVSPSGLKYNQKLAYDLSKKDELVIICGRYEGLDQRIIDLYVDFEISVGDYVLSSGEVAALVIIDSVYRLLEGVINPNSLLEESFSCECGLLEYPHYTRPYEFKGLEVPNVLLSGHHEEIRKWRFMKSIEKTKKNRYDLYLKYLEMRGENDGFNKKN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAI14_HUMAN
Sequence: MKSLKAKFRKSDTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK
What is the function of this protein?
Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis.  Important for establishment of sperm polarity and normal spermatid adhesion.  May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
What are the official names of this protein?
Ankycorbin, Ankyrin repeat and coiled-coil structure-containing protein, Novel retinal pigment epithelial cell protein, Retinoic acid-induced protein 14.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus. Note=Associated with the cortical actin cytoskeleton structures in terminal web and cell-cell adhesion sites (By similarity). Highly expressed at the ectoplasmic specialization, an actin-rich cell junction specific to the testis (By similarity). Predominantly nuclear in nonconfluent cells (PubMed:16729964).
Protein: NUOB_COXBR
Sequence: MQQLLTKEGFLLTSLDDLMRWARSGSLWPMTFGLACCAVEMMQCASSRYDLDRFGAGLFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYAYSVVRGCDRIVPVDVYVPGCPPTAEALFYGIMQLRNKIRYRNIFDRKDA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HORM1_BOVIN
Sequence: MATAQLQRTSMSALIFPNKISTEQQSLVLVKRLLAVSVSCITYLRGIFPECAYGTRYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALHKKYLRMVVLAVYTNPEDPQTISECYQFKFKYTSNGPVMDFTSKNQSNEPNMSSADTKKASILLIRKIYILMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDGDCEGVIFEGEPMYLNVGEVPTPFHTFKVKVTTERERMENIGSGILSPKQLKTPLQKILTDKDDLEDDQEHYISDEFDTETKMEEQEKNPGCSVRREAGFICEEDEMKSKGSPDFSISHSQVEQLVSKTSELDVSESKTRSGKIFQNKMANGNQQVKSKENRKRTQLESGKTVLHPFDSSSQESVPKRRKFSEPKERI
What is the function of this protein?
Plays a key role in meiotic progression.  Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends.  Promotes synaptonemal-complex formation independently of its role in homology search.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
What are the official names of this protein?
HORMA domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser- 376 is restricted to unsynapsed chromosomal regions (By similarity).
Protein: LPTD_NITEU
Sequence: MNTLKLCLILYACLVLLPVRVMSADLSPASSERQPIYIEADHIDGHYQQEIEAIGNVRMRRGDQTLTADRVKYYQSNENVEVEGNAQLERPDDILWGSYLQMNLNDNTGQLSEPRYLQKDGNGRGDGNLLLLEGENQYRFKKARYTTCPEDDHDWYILADDLEIDKEKKVGTARHASVRFKDVPILYVPWMNFSFGNERKTGFLSPIMGNTSRSGVEVSVPFYWNIAPNYDATITPRLMSRRGVMLNNEFRYIGQTLNGRFLLDYLPNDLETDTTRYGMQLNHFHNLGAGWFGMINYNSASDRNYFRDLGNNILFTSQTNLLQQGFASYFRELGRNGTLTFSTLLQQFQTLQDPRAPIISPFKILPRFTLNAAKRNVYGLDFDFSGSFTHFSHSTLPHGLRTTFLPGVSLPLENSFGFIRPRVSLHHTRYDLNEPANPAANDKHLSRTVPIFSFDSGIVLERDTTLARENFVQTIEPRVFYTYIPYRDQQLLPNFDSAEMDFSYPQLFLERRFSGEDRINDANEITLAVSSRLIHSATGNERLRFSAGQRIRFSDRRVILTSPQVTRAGSDFIAELSGGITQNIKTDTGIQLNQNNFLIEKIRTGISYRPAPGKVINAGYRFTRDVLEQVDLSTQWPFLKKWQGFAAINYSLKDDKLLAGLLGLEYNACCWSLRFVTSHFTTATQRTSTNIFVQLELNDLMRIGTNPVRVLQQTIPGYMRTDL
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS2_CAMJD
Sequence: MVSMRDLLECGVHFGHQTRRWNPKMKKFIFGERKGIYVIDLQKTLRYFRYTYNIVRDAAAEGKTILFVGTKKQAGGALKEYAEKCGMPYVNHRWLGGMMTNFGTIRQSIRKLEVIEKMEEDGSIKLLTKKEALMLTRKKEKLLAYLGGIRYMKTQPDMIFVIDTVKEKIAVQEANRLRIPVVAPLDTNCDPDLVTYPIPGNDDAIRSVQLFCQEMAEAINEGKALREQDGEALPNEEKEITDEEKKEVLDESMSEEDFGEEQE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL35_CORDI
Sequence: MKQKTHKGTAKRVKITGSGKLRREQANRRHLLEGKPSKRTRRLKGTEDVAKADTKRIKRLLGKA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CXCR2_HUMAN
Sequence: MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
What is the function of this protein?
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716).  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698).  Binds to IL-8 with high affinity.  Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
What are the official names of this protein?
C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CDw128b, GRO/MGSA receptor, High affinity interleukin-8 receptor B, IL-8R B, IL-8 receptor type 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KNOS7_ORYSJ
Sequence: MEELEGHRGEGRLPPPPPLLPFPKVSVQVYTVPSSSTAASAAAAGGARQAVAPATRDGGDGGGRAAGVLDDPVKARIVSHPRYHRLLAAFLDCHKVGCPAEAAEEIAAAARVREARQRAAAAASRMPPAPEDPELDQFMEDYCKLLVECKEELSRPLQEAEEFLRTVESELNSINSGPPLTALISESKAGLDSSDDDEHEDGSGMEMMEAAEDEDLGIIDPRSDDKALKRHLLRKYSGYLGGLRKELSKKRKKGKLPKEARQKLLTWWELHYRWPNPSEMEKIALAESTGLEQKQINNCFINQRKRHWKPTEEMEFAVMEAYHHQSTDAAAAFYVDVDARLVGATAAAPASAVYTARPDHGVWRA
What is the function of this protein?
Probable transcription factor that may be involved in shoot formation during embryogenesis.
What are the official names of this protein?
Homeobox protein knotted-1-like 7, Homeobox protein HOS13, Homeobox protein OSH3.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.