PharMolix/UniProtQA huggingface dataset:
Protein: SEQA_IDILO
Sequence: MKRIDIDDDLYTYIASHTRQIGESASDILRRLLDVNSSEPEADSKSEPTESVFNRLNEQDVRIQKSVVARFLYILSMLYRCHPSEFSQVLDIRGRDRQYFARSEEALLTSGNSTNPKQIPDSPFWVITNTNTTKKKAMLTQVAEKLGYQSADAEKIRDFL
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_NEIG1
Sequence: MQLHILNNPKDAALAADAEFLKQSLFNLLHEEASPLVVETVKLLSTSDDSAALIEKVLPQLDERQTYDLTLACGLFAQILNIAEDVHHERRRQIHEDAGHNAAEGSLTETVRRLKAGKADGKSVQRQLDNTSVTAVLTAHPTEVQRQTVLNFNRRIRALLPQRERCTNADALARLRREIDTVLLGLWQTSETRRHKLSVNDEINNGVSIFPMSFFEALPKLYRKMEHDFQTAYPDVRVPNILKIGGWIGGDRDGNPFVSGETLRFAFRRHADAVFRFYRSELDKLYRELPLSIRRVKVNDDVMALAALSPDEEIARTEEPYRRAIAYIMARAMGKARSLGLGMGCKFGFLEPYASAQKFLDDLKKLQRSLIDNGSRLLAEGRLADLIRSVSVFGFHMMPLDLRQHAGKHADVVAELFQHAGLEDYNSLNEEQKQAALLRELGHQRPLYSPFITYSDHTRRELAIFNEARKIKDEFGEDAVTQSIISNCEQPGDLLALALLLKESGLLAVENGKPHSRINIVPLFETIEALENACPVMETMFRLDWYDALLESRGNIQEIMLGYSDSNKDGGYVTSSWCLHQAELGLVELFKKYDVRMRLFHGRGGSVGRGGGPSYQAILAQPAGSVAGQIRITEQGEVITAKYADPGNAQRNLETLVAATLEASILPDKKDPDAKLMQALSDVSFKYYRELITHPDFIDYFLQTSPIQEIATLNLGSRPASRKTLARIQDLRAIPWVFSWMQNRLMLPAWYGFGSAVETLCEGSPETLAALRGHAQNNPFFQAMLSNMEQVMAKTDITLAENYAGLSESPEKAKVIFGMIKEEYRRSRKALLDLLQTEELLRDNRSLARSLALRIPYLNALNGLQVAMLKRLRKEPDNPHALLMVHLTINGVAQGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: RIC3_MOUSE
Sequence: MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLDRFPPMMHHHSAPSDGQTPGARFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTAEDRNCSTAPPGNAHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQAVTSDQEKRLLHQLREITRVMKEGKFIDTSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDLKEPSAEEIAEQMGEIEEEGSERLSWDHLPTDPGAQKDNSVAPCDPKPESCSCCVHEEEDPAVLAENAGFSADGYSEQEEATKENLPQDFTNEGLGVSTDNAHVGGMLRKRNPQGFE
What is the function of this protein?
Molecular chaperone which promotes the proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) nicotinic acetylcholine receptor (PubMed:19812337, PubMed:32204458).  Promotes the proper subunit assembly and cell surface expression of alpha-8 (CHRNA8) nicotinic acetylcholine receptor (By similarity).  May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4 (By similarity).
What are the official names of this protein?
Protein RIC-3, Resistant to inhibitor of cholinesterase 3.
What is the protein family that this protein belongs to?
Belongs to the ric-3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GPPA_ECOLU
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLAQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVKNEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: METN1_BACCZ
Sequence: MIELKNVSKVFTTKKGNVEALKSTSLQVKKGEVFGIIGYSGAGKSTLIRCVNLLEKPTTGNIIVNEQDLTTLSTKELAKARQKIGMIFQGFNLLKTVTVYENIALPLRLAGVPKLEIEKRVEKYLRIVDLFNRKDAYPSELSGGQKQRVAIARALSHEPEVLLSDEATSALDPETTDSILDLLLKINEEIGITILLITHEMNVIQRICDRVAVMEHGAVIESGTVKEIFTNPQHVTTKKFVNSAFAAKIPAEVQKELQRTGEIVTLSFIGNSSGEPALAIATKRFQVYPNILSGNITQLKHEAYGKLVIHMQGEKNEVDRALSFLQEQGIIVEGGRTDYGKQVLFG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FIMBF_DICNO
Sequence: MNKQRFLFAAKISGIHFLLSLTVAVLLAGLIFFVWYPFPYQKIMGNFK
What are the official names of this protein?
Fimbrial assembly protein, serogroup F1.
Protein: RS2_RHIL3
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMKPYIFGDRNNIHIIDLAQTVPMLSRALQVVSDTVARGGRVLFVGTKRQASEIIADSAKRSAQYYVNSRWLGGMMTNWKTISNSIQRLRKLDEILNGEAQGFTKKERLNLEREREKLDKALGGIRDMGGTPDLMFIIDTNKEKIAIDEAKRLGIPVVAIIDSNCDPDLIDYPIPGNDDASRAIALYCELISRAAIDGIARQQGSSGRDLGASSEVPVEPALEEAAEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MNMG_NATTJ
Sequence: MAYYGGNYDLIVVGAGHAGCEAALAGARIGAKTLLLTLNLDQIALMPCNPAIGGPAKSHIVREVDALGGEMGKNIDDTAIQFRMLNTRKGPAVQALRAQADKIKYQERMKYILENEENLLLKQETVNQLMIEDNQIKGVVTKDGTYYYCEQLVITSGTYLKGRIIVGDVDYSGGPNGQQAAYGLSEDFKQHGISLMRFKTGTPARVYRKSLNFDEMEIQHGDDYPWRFSFYHSSERLKQLPCYLTFTNYETHKIINDSLSRSPLYSGRIEGTGPRYCPSIEDKIVRFPDKSRHQLFLEPEGLNTQEYYVQGMSTSLPLDVQERMLRTIPGLEEVEIMRPGYAIEYDCIDPTQLELTLEHKQISGLFFAGQINGTSGYEEAAGQGILAGINAAQKIQGKEPVIIKRSQGYIGVLIDDLVTKGTQEPYRMLTSRAEYRLILRQDNADLRLTELGYQVGLIKEGNYQKFKEKLEKIESEKERLKSIKLTPNKNVQNFMEEHNTSGLKKPTTLFHILKRPEISYEALEYFDETRPDLPLEVTEQIEIQIKYEGYIDKQVEQVQRFEKLEARLIPDDIDYSQISGLSIEAREKLQTYRPRSVGQANRISGIDPSDISVLMVYLEQLKQRADRNQASHDDSNTETGENDD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGL_ECOLI
Sequence: MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHFG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid (PubMed:218816, PubMed:6277376, PubMed:6303781, PubMed:2984194, PubMed:3009449, PubMed:2828054, PubMed:9305868).  Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis (PubMed:217867, PubMed:6305970).  In vitro, phosphorylates various substrates, including sn-1,2-dioleoylglycerol, sn-1,2-dioctanoylglycerol, sn-1,2-dipalmitoylglycerol, sn-1,2-dipalmitate and ceramide (PubMed:218816, PubMed:2984194, PubMed:3009449, PubMed:3021764, PubMed:2828054).  Catalyzes direct phosphoryl transfer from Mg-ATP to diacylglycerol and does not form an enzyme-phosphate intermediate (PubMed:9305868).
What are the official names of this protein?
Diacylglycerol kinase, DAGK, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the bacterial diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_PEDPA
Sequence: MGKKRIYELAKEINVSSKDIIEKAQADGLDVKNHMSTLDDASEKHLRNAFKKNTTTTKPEEKRTPKFRSSKTGKTVVKKSDHPAADGTKGIQRLKSSNNESTTRNNNNNKNGNQNRNNTNGRPNNNQNRPNNNRNQNNNRNGNRPNQPKRDEKQDRIRASVAEAARMAAQANREIANEKPQANRQRTNSAKPGEQRREGRNNQNRPNNNNRNGNNVNRTNNNNRPNNNNRNNENRPSRPNNTNQTTNNRPANNTTRPAAPAATTANNSGEKKQDRFSGRNNNSRGGNRFGNNQNRPFNKENRKNKKRNRKAKRDGRMKETTNKVVTVRKERPLPDVLEYSEGINVAEIAKKIHREPAEIIKKLFMMGVMVNQNQSLDNDTVELLAADYGIEAQQKVEVDISDIDKIFEDEEKNTTNLVSRPPVVTIMGHVDHGKTTLLDKLRHSHITEGEAGGITQGIGAYQLKHDDKLITFLDTPGHAAFTEMRARGADVTDITILVVAADDGVMPQTIEAINHAKAANVPIIVAVNKIDKQGANPNHVMEQLTEYGLIPESWGGDTIFVEISAKLGQNIDELLDMILLQAEVLELKANPDQNAAGSVIEAQLDPGKGSIATILVQQGTMHVGDPIVIGNTFGRIRTMVNEHGRRVKEATPSTPVEITGLNGVPEAGDRFVVFDDEKSARAAGEERAKRAQMEERKRSNHVTLDNLFDSLKEGEMKKVDIIIKADVQGSVEALADSLQKIEVEGVRVNIIHKAVGAINESDVTLAAASNAIIIGFNVRPTAQAKQMADSEDVDIRLHRVIYNAIDEVESAMKGMLEPVYEEEIIGQVDIRETYKVSRVGTIAGGFVTEGFITRDSGVRLIRDGVVIYEGKLGSLKRFKDDVKEVKRGFELGLTVENYNDIKIGDVIEAYRMKEVPVE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_VIBPA
Sequence: MPIITLPDGSQRQFDNPVSTMEVAQSIGPGLAKATIAGRVNGNRVDACDLIEEDASLEIITVKDEVDGLEIVRHSCAHLLGHALKQLYPQAKMAIGPTIDNGFYYDIDLDESLTQEDLEKIEKRMKELAKTKYEVVKKKVSWQEARDTFESRGEPYKVEILDENVSRDDRPGLYHHEEYIDMCRGPHVPNMGFCQHFTLLNVAGAYWRGNSDNKMLQRIYGTAFHDKKALKAHLTRLEEAAKRDHRKIGKQLDLFHMQQEAPGMVFWHHNGWSIFRDLEVFVRDKLNEYDYQEVKGPLMMDRVLWERSGHWDKYADAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGIMRVRGFTQDDAHIFCTESQIQEEVTSCIKMVYDTYQTFGFDNIVVKLSTRPEKRVGSDEIWDQSEEALKQSLESMEIPYEIQEGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFNLPGRLGATYVGENNERLVPVMIHRAILGSLERFIGILIEEYAGFFPTWLAPEQAVLMNITDKQSGYVQEIVQKLQKSGIRAKADLRNEKIGFKIREHTLKRVPYMLVVGDQEMEAGEIAVRTRKGKDLGKFKVDDFIAYIQDEISSRKLNLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXM_SPIOL
Sequence: MAIENCLQLSTSASVGTVAVKSHVHHLQPSSKVNVPTFRGLKRSFPALSSSVSSSSPRQFRYSSVVCKASEAVKEVQDVNDSSWKEFVLESEVPVMVDFWAPWCGPCKLIAPVIDELAKEYSGKIAVYKLNTDEAPGIATQYNIRSIPTVLFFKNGERKESIIGAVPKSTLTDSIEKYLSP
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The M form is known to activate NADP-malate dehydrogenase.
What are the official names of this protein?
Thioredoxin M-type, chloroplastic, Trx-M.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant M-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DPD1_ARATH
Sequence: MCISISQVSRLRIHSFGSSCCERVHGWIKNSSSLKLLDVRASSVDGKARWIRRNVSTTTQGSRSNTKSSVLGGTVPVTRIIDEESRTKVQPFGNLQQRLAQDKDLSKLLTVIVSDLETTGLHRKNERIIEIAAQDIAGGGYSTFQTLVNPGVVPITNAHIHGIRNDMVCRPEVPRMEELIPIFLRYVESRQKPGGYVMLVAHNGKSFDFQFLINEFNRCSYEIPHNWLLLDSLPLARENMKSVEPTVKLSSSLEALADYYSLTREGDAHRALSDVLLLSKVFQKLTIDLKLSLSDLVLRCHTASDISAAMAKNKKA
What is the function of this protein?
Exonuclease required for organelle DNA degradation during pollen development.  Plays non-essential roles in maternal inheritance.  May be part of the DNA salvage machinery.
What are the official names of this protein?
Exonuclease DPD1, chloroplastic/mitochondrial, Mg2+-dependent DNA exonuclease, Protein DEFECTIVE IN POLLEN DNA DEGRADATION 1.
What is the protein family that this protein belongs to?
Belongs to the exonuclease superfamily. TREX family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: YIDC_PSEP1
Sequence: MDIKRTILIAALAVVSYVMVLKWNDDYGQAALPTQNTAASTVAPGLPDGVPAGNNGASADVPSANAESSPAELAPVALSKDLIRVKTDVLELAIDPVGGDIVQLNLPKYPRRQDHPNIPFQLFDNGGERVYLAQSGLTGTDGPDARASGRPLYAAEQKSYQLADGQEQLVVDLKFSDNGVNYIKRFSFKRGEYDLNVSYLIDNQSGQAWSGNMFAQLKRDASGDPSSSTATGTATYLGAALWTASEPYKKVSMKDIDKGSLKENVSGGWVAWLQHYFVTAWIPAKSDNNVVQTRKDSQGNYIIGYTGPVISVPAGGKVETSALLYAGPKIQSKLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSLLGNWGWSIIVLTMLIKGLFFPLSAASYRSMARMRAVAPKLAALKERFGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLALYWVLLESVEMRQAPWILWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNCLSISQQWYITRRIEAATKKAAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_LEGPC
Sequence: MEVTAKLKGAPLSAQKGRLVADMIRNMNVSGALDVLKFTPKKGAKLMLKLLESAIANAENNNGADIDDLKVGMVCVDEATTLKRISPRAKGRANRICKRTCHITIKVSDEE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RNH_SHELP
Sequence: MHGLKQLLIFTDGSCLGNPGPGGYGVVMKYKAHVKELSGGFALTTNNRMELLAPIMALEALKEPCQIILTSDSQYMRQGITQWIHGWKKRGWLTAAKEPVKNVDLWQRLDAATSTHKIDWRWVKGHAGHIENERCDTLAREAAEAGPSEVDTGYQAKG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PK22_PSEAE
Sequence: MFESAEVGHSIDKDTYEKAVIELREALLEAQFELKQQARFPVIILINGIEGAGKGETVKLLNEWMDPRLIEVQSFLRPSDEELERPPQWRFWRRLPPKGRTGIFFGNWYSQMLYARVEGHIKEAKLDQAIDAAERFERMLCDEGALLFKFWFHLSKKQLKERLKALEKDPQHSWKLSPLDWKQSEVYDRFVHYGERVLRRTSRDYAPWYVVEGADERYRALTVGRILLEGLQAALATKERAKRQPHAAPLVSSLDNRGLLDSLDLGQYLDKDAYKEQLAAEQARLAGLIRDKRFRQHSLVAVFEGNDAAGKGGAIRRVTDALDPRQYHIVPIAAPTEEERAQPYLWRFWRHIPARRQFTIFDRSWYGRVLVERIEGFCAPADWLRAYGEINDFEEQLSEYGIIVVKFWLAIDKQTQMERFKEREKTPYKRYKITEEDWRNRDKWDQYVDAVGDMVDRTSTEIAPWTLVEANDKRFARVKVLRTINDAIEAAYKKDK
What is the function of this protein?
Uses inorganic polyphosphate (polyP) as a donor to convert AMP to ADP.  Can also convert GMP to GDP, with lower efficiency.  Cannot dephosphorylate ADP in the presence of polyP.
What are the official names of this protein?
Polyphosphate:AMP phosphotransferase, PAP, Polyphosphate kinase PPK2 3.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class II subfamily.
Protein: MT_BALMY
Sequence: MDPNCSCAAGGSCTCAGSCKCKECKCTSCKKSCCSCCPPGCTKCAQGCVCKGASDKCNCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: ASTA_SALA4
Sequence: MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSDELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: RRP3_ASPNC
Sequence: MPGVKKRKVAREAPAPAPAQESDVESSTPEQTQEPEAQEQEQEEGQSKTFKELGIIEQLCEACETMGYKAPTPIQRESIPLALKGRDLIGLAETGSGKTAAFALPILQALMEKPQPFFGLVLAPTRELAYQISKSFESLGASMGVRSCVIVGGMDMVSQSISLGKKPHIIVATPGRLLDHLENTKGFSLRNLKYLVMDEADRLLDMDFGPLLDKILKVLPRERRTFLFSATMSSKVESLQRASLSNPLRVSVSTSKYQTVSTLLQSYLFIPQKHKDLYLVYLLNEFAGQSTIIFTRTVNETQRLAFLLRALGFGAIPLHGQLSQSARLGALGKFRARSRNILVATDVAARGLDIPSVDVVLNFDLPGDSPSYVHRVGRTARAGKSGLAISFVAQYDVEVWLRIEGALGKKLKEYDCPKDEVMVLGENVAEAQRQAIMDMKDYNEKKGSRGKKFGGKRSRDEMDQEEG
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase rrp3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPV17_DROME
Sequence: MKRLKAYLKDGINVAAVMCLGDTISQFFFDKKSLDEWDAGRTLRFGIVGLVFVGPTLRRWYHFLESRVPKTYSPMRRGVTKMLVDQTLFAPPFTMAMSFLVPLSNGEPIDRIRQRILDSYLSILVRNYMLWPAAQMLNFRFVPLGYQVLYAQFIALVWNCYLSMILNS
What is the function of this protein?
Involved in mitochondria homeostasis.
What are the official names of this protein?
Mpv17-like protein.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SRGN_RAT
Sequence: MRQVPVGTRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESNVGPPMTDPVLMRGFPNDFFPISDDYSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSLADMEWEYQPTDENNIVYFNYGPFDRMLTEQNQEQPGDFII
What is the function of this protein?
Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles.  Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes.  Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.  Mediates processing of MMP2.  Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis.  Regulates the secretion of TNF-alpha and may also regulate protease secretion.  Inhibits bone mineralization (By similarity).
What are the official names of this protein?
Serglycin, Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, PG19 core protein, Proteoglycan 10K core protein, Secretory granule proteoglycan core protein.
What is the protein family that this protein belongs to?
Belongs to the serglycin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cytolytic granule. Secreted, extracellular space. Golgi apparatus. Note=Found in mast cell granules and in cytoplasmic granules of cytolytic T-lymphocytes from where it is secreted upon cell activation. Secreted constitutively by endothelial cells and macrophages. Located to Golgi apparatus during neutrophil differentiation (By similarity).
Protein: PSBE_COFAR
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NEF_HV1Y2
Sequence: MGGKWSKRSMAGWPTVRERMRRAEPAAERMRRAEPAADGVGAVSRDLERHGAITSSNTAATNADCAWLEAQEEEEVGFPVRPQVPLRPMTHKAAMDLSHFLKEKGGLEGLIHSQQRQDILDLWVYHTQGYFPDWQNYTPGGTRWPLTFGWCFKLVPVEPEKIEEANAGENNCLLHPMSQHGMDDPEREGLEWRFDSRLAFHHVARELHPEYYKN
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: PRMA_ECOLI
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THRC_SYNY3
Sequence: MISCHSFTMTPSAPNSTVLPSATPVCPQSSACRWRGLIETYRPYLPVSDQTPVVTLLEGNTPLIPAPAIAKRIGKDVRVFVKYDGLNPTGSFKDRGMTMAISKAKEAGAKAVICASTGNTSAAAAAYARRAGLRAFVIIPDGYVALGKLGQALIYGAEVIAIDGNFDDALTTVRQLSEHYPVTLVNSVNPYRLEGQKTAAFEIVDVLGQAPDWLCIPVGNAGNITAYWMGFCQYKELGKGDRLPRMMGFQAAGSAPFIQGQPISHPETLATAIRIGNPANWDKAWAASRESNGEFHPVTDAEILEAYRILAAEEGVFCEPASAASVAGLLKQKDQVPAGATVVCVLTGNGLKDPDCAVQNSGNQVKAGLKPDLEIVAKAMGF
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.