PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_PSELT
Sequence: MAEKYILALDQGTTSSRAIIFNQAGETVCMVNQEFPQLYPEPGWVEHDPVDIIESQISVAKKAIEIASINPDQIAAIGVTNQRETTIVWDKNTSKPVYNAIVWQCRRTASMCDQFKKLGYEDTIRKKTGLVLDAYFSATKLKWILDNVEGARQKAERGELLFGTVDSWLIWNLTGGKIHATDYSNASRTMLFNIHSLNWDEELLELFNIPEQMLPDVLPSSTVYGYTHKEIFGVEIPICGNAGDQQAALFGQICCEPGMVKNTYGTGCFILMNTGNKIVDSKHGLLTTIGWVLNDKSMCYALEGSVFSAGATVQWLRDGLKIVEKASDTEYLAKSVKDSAGVYFVPAFVGLGAPYWDMYARGTIIGITRGCTREHIVRAALESIAYQTRDVVEVMSEESGIKLHCLRVDGGASANDFLMQFQADILGVPVERPTVSETTALGAAYLAGLAVGYWKDHSEIKKQWRLDRRFEPQMDPETREELYKKWKNAVTRSLGWVEK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AAT_SACS2
Sequence: MVSLLDFNGNMSQVTGETTLLYKEIARNVEKTKKIKIIDFGIGQPDLPTFKRIRDAAKEALDQGFTFYTSAFGIDELREKIAQYLNTRYGTDVKKEEVIVTPGAKPALFLVFILYINPSDEVILPDPSFYSYAEVVKLLGGKPIYANLKWSREEGFSIDVDDLQSKISKRTKMIVFNNPHNPTGTLFSPNDVKKIVDISRDNKIILLSDEIYDNFVYEGKMRSTLEDSDWRDFLIYVNGFSKTFSMTGWRLGYIVAKREIIQKMGILAANVYTAPTSFVQKAAVKAFDTFDEVNQMVSLFKKRRDVMYDELTKVKGVEVSKPNGAFYMFPNVSKILKTSGFDVKSLAIKLIEEKGVVTIPGEVFPLNIGKEFLRLSFAVNEEVIKEGIQKIREFAEQMMNSR
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_XANCP
Sequence: MRPIDRQIYRPPDFRTTFLQTADTKDKTKLSTGAAEHTPLMKQFFAAKSDYPDLLLFFRMGDFYELFYDDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLVALGESVAICEQIGDPALAKGLVERKVVRIVTPGTVTDEALLDERRDTLLMAISRSKQGYGLAWADLAGGRFLVNEVDSVDALEAEIARLEPAELLVPDEDNWPEFLRGRVGVRRRPPWLFDADSGRRQLLAFFKLHDLSGFGIDDKPCATAAAGALLGYVEETQKQRLPHLTSIAMEVASEAISMNAATRRHLELDTRVDGDTRNTLLGVLDSTVTPMGGRLLRRWLHRPLRLREVLVQRHHAVGSLIDTGADTDVREAFRALGDLERILTRVALRSARPRDFSTLRDGLALLPKVRTILAPLDSPRLQTLYAELGEHDATAHLLISAVAEQPPLKFSDGGVIATGYDADLDELRRLSTNADQFLIDLEQRERASSGIATLKVGYNRVHGYYIEISKGQAEKAPLHYSRRQTLTNAERYITEELKSFEDKVLSARERSLSREKLLYEGLLDALGGELEGLKRCASALSELDVLAGFAERAQALDWSQPELESAPCLHIERGRHPVVEAVRDQPFEPNDLDLHPDRRMLVITGPNMGGKSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRILTRIGAGDDLARGQSTFMVEMAETSYILHHATPQSLVLMDEIGRGTSTYDGLALADAVARHLAHTNRCYTLFATHYFELTALADASHAGGGSGIANVHLDAVEHGERLVFMHAVKDGPANRSFGLQVAALAGLPKAAVQQARRRLAELEQRGGDSHAAEMAPAALDAPQQFGLFTAPSSAAQEALQALDPDELTPKQALEALYRLKALL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MCDP_BOMPE
Sequence: MCICKNGKPLPGFIGKICRKICMMQQTH
What is the function of this protein?
Mast cell degranulating peptide.
What are the official names of this protein?
Mast cell degranulating peptide, MCD peptide, MCDP.
What are the subcellular locations of this protein?
Secreted.
Protein: NS1_I96A0
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETNENLKIAIASSPAPRYITDMSIEEMSREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTESGAIVAEIFPIPSVPGHFTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIHDENGGPSLPPKQKRYMAKRVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: CRCB_PASMU
Sequence: MISVGQQIIFISSGAALGALSRWGLGLLLNPLFSAFSLGTLVANYLGCLIIGVFLAFFWQYPQCSAEWRLFFVTGFLGSLTTFSTFSAEVIENLIQQKWLAGLMLASGHLLGCLLFTALGVFIWRYWQ
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELO_ALKCK
Sequence: MTEQAKWNFDNSYARLPQPFFARLKPNPVRSPKLVLFNEPLATALGLNGEALQQPEGVAVLAGNVIPEGGEALAQAYAGHQFGHFTMLGDGRALLIGEQITPDGNRFDIQLKGSGRTPFSRGGDGRAALGPMLREFLISEAMHALGIPTTRSLAVVTTGEEIWRETELPGAVLTRVAESHLRVGTFQYAAGRGEVNDVKTLADYAIKRHYPELAESENPYLSLLEQVITRQANLISQWQLVGFVHGVMNTDNMTISGETIDYGPCAFMDTYDPATVFSSIDTQGRYAYGNQPQIANWNLARFAETLVPLLAEDETKGVEMAQSAIEGFKGQYVSNWLAGIRKKLGLFNAEDGDKDFVEKLLRLMHEHEADYTNTFRLLTLGQPEKTAMNGAAEFSEWLEQWQQRQSRQAQTKDEAMKLMRTNNPAVIPRNHRVEEALAAAVDEEDDSLVKQLIAVLKEPYAYSEEQERYAEVPERCQHGYVTYCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: UGPI2_ARATH
Sequence: MAISKLHLVLFLLSVFLSLHRPVLSNTDGENLLFTVFNQYRESVNLTNLKKNKNAECLADEVVDQLQNQPCTNTTGSASVPGTDPGIPNFPNLLAKCRLNTNVTRDGLILQVCAPKHHSTPDLSSFANVLTKNLNDSKFTGAGVGIDSDGIWLVTVLTTNTPGGSYSNSGAFAFGVNGLVSSSLMFLHVLSHNSLSLFS
What are the official names of this protein?
Uncharacterized GPI-anchored protein At5g19240.
What is the protein family that this protein belongs to?
Belongs to the UPF0277 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: IDHC_MICOH
Sequence: MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (By similarity).  Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (By similarity).  May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: UPPP_STRS7
Sequence: MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKAFMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIAVPLDDWFEAHFNHMLPIAIALIVYGVAFLWIEKRHQTLEPRVVKLSRMSYKTAFFIGCFQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGNHLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFKSLF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAJ_AMBTC
Sequence: MRDIKTYLSVAPVLTTLWFGALAGLLIEINRFFPDALAFPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LLDD_ECOBW
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU3M_CHICK
Sequence: MNTLTFMLSLSFLLSAALTTMNFWLAQMAPDTEKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAIQLAHPMMTLTWATTIIALLTFGLIYEWTQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IVBS5_OXYSC
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFYELPADIGPCEDFTGAFHYSPREHEYIEFIYGGCEGNANNFNTLEECET
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Scutellin-5.
What are the subcellular locations of this protein?
Secreted.
Protein: THIM_BACP2
Sequence: MKTSIASHLLEKVRAENPLVHNITNQVVTNFTANGLLALGASPVMANAKEEVAEMAQLADALVLNIGTLTKETVESMILAGQSANKKGIPVLLDPVGVGATTFRLKAAKQLLEQVNITVVRGNAAEIAHLLEVDGWESKGVDAKAANGDVSALVKQAAKTLQTVVVITGEVDVVSDGEDVLSIHNGHEWLTKVTGTGCLLTSVIGAFCAAGERPLHASAAALLFYGVAAEKAAQYTQNKGPGTFQMELLNALSHTTGNDVLTLGKIGRNVT
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ACOX1_HUMAN
Sequence: MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVRKSAIMVKKMREFGIADPDEIMWFKKLHLVNFVEPVGLNYSMFIPTLLNQGTTAQKEKWLLSSKGLQIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAEVHESYKHLKSLQSKL
What is the function of this protein?
Is active against a much broader range of substrates and shows activity towards long-chain fatty acyl-CoAs.
What are the official names of this protein?
Peroxisomal acyl-coenzyme A oxidase 1, AOX, Palmitoyl-CoA oxidase, Peroxisomal fatty acyl-CoA oxidase, Straight-chain acyl-CoA oxidase, SCOX.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: YOUD_SCHPO
Sequence: MVIKRGFIGNTPKPSRCKRTKPIFREPNSPVNGGLVYNHPLHTAAAVKEAFSENRGFRTCHVCHRKNNMRLKVGTCESCKKHTCAICIRQCHKCESNVCSMCSKQERTFESEAFCPSCYPLDTY
What are the official names of this protein?
Uncharacterized protein C26H8.13c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMG_SALTO
Sequence: MPGAVSATPPPELATAARTLFGDRLSLAVAYAGLLVTDGVVRGLIGPREAPRIWDRHLLNCAAVAERIPLGSTVLDVGSGAGLPGLVLAVARPDLSVTLVEPLARRTAFLVEAVAQLDLAASVQVVRGRAEEIASGGGGVEPLTGDVVTARAVAPLDRLARWCLPLAVPGGRLVALKGASAVEEVAEHAAIVDRLGGGRPEVHHCGAGVVEPPTTVIEIARERVVAPARPKPAKRSRGGRRR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCASE_MYCTU
Sequence: MLSVGRGIADITGEAADCGMLGYGKSDQRTAGIHQRLRSRAFVFRDDSQDGDARLLLIVAELPLPMQNVNEEVLRRLADLYGDTYSEQNTLITATHTHAGPGGYCGYLLYNLTTSGFRPATFAAIVDGIVESVEHAHADVAPAEVSLSHGELYGASINRSPSAFDRNPPADKAFFPKRVDPHTTLVRIDRGEATVGVIHFFATHGTSMTNRNHLISGDNKGFAAYHWERTVGGADYLAGQPDFIAAFAQTNPGDMSPNVDGPLSPEAPPDREFDNTRRTGLCQFEDAFTQLSGATPIGAGIDARFTYVDLGSVLVRGEYTPDGEERRTGRPMFGAGAMAGTDEGPGFHGFRQGRNPFWDRLSRAMYRLARPTAAAQAPKGIVMPARLPNRIHPFVQEIVPVQLVRIGRLYLIGIPGEPTIVAGLRLRRMVASIVGADLADVLCVGYTNAYIHYVTTPEEYLEQRYEGGSTLFGRWELCALMQTVAELAEAMRDGRPVTLGRRPRPTRELSWVRGAPADAGSFGAVIAEPSATYRPGQAVEAVFVSALPNNDLRRGGTYLEVVRREGASWVRIADDGDWATSFRWQRQGRAGSHVSIRWDVPGDTTPGQYRIVHHGTARDRNGMLTAFSATTREFTVV
What is the function of this protein?
Catalyzes the cleavage of the N-acyl linkage of the ceramides (Cers) to yield sphingosine (Sph) and free fatty acid.  Also catalyzes the synthesis of Cers from Sph and fatty acid.  Cers containning C6-C24 fatty acids are well hydrolyzed, and Cers with mono unsaturated fatty acids are much more hydrolyzed than those with saturated fatty acids.
What are the official names of this protein?
Neutral ceramidase, N-CDase, NCDase, Acylsphingosine deacylase, N-acylsphingosine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the neutral ceramidase family.
Protein: GSA_PSEPF
Sequence: MSRSETLFANAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVTDEDDKRYVDYVGSWGPMILGHSHPDVLDAVRNQLQHGLSYGAPTAMETEMADLVCSLVPSLEMVRMVSSGTEATMSAIRLARGFTGRDSIIKFEGCYHGHSDSLLVKAGSGALTQGVPSSAGVPAAFAKHTLTLPFNDIDAVEKMLAEVGQDVACIIVEPVAGNMNCVPPAPGFLEGLRSLCDKHGVVLIFDEVMTGFRVALGGAQAYYGVTPDLTTFGKIIGGGMPVGCFGGKRLIMERIAPLGPVYQAGTLSGNPLAMAAGLTTLRLISRPGFHAELTDYTTRLLDGLQQRADAAGIPFVTTQAGGMFGLYFSGADDIVTFEDVMASDAALFGRFFHLMLEGGVYLAPSAFEAGFTSIAHGEAELKLTLDAAERAFAKLK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_LEPBJ
Sequence: MSETQKENPYSSTVLLPKTDFPMKADLAKREPEQIRSWKQNRIFRKMREQRSGKKEFVLHDGPPYANGNFHLGHALNKILKDTIIKSKSLAGFYADMIPGWDCHGLPIEVQVLKNLGKKVRETGPEELRQLCRKYAEEFVGKQGDDLSRFLCFWDEGRIYKTMSPDFEAKIVEVFGELFKKGYVYRGKKPVYWSIDLATAHAEAEIEYYPHISPSIYVKFPIIGEKKRFCLIWTTTPWTLPANLAICFNRKIEYSIFKTESSEELILADALAENVTITTGVALTKLKPITSEELAALKFQHPFVDRISVSLFGDHVTLEAGTGCVHTAPGHGQDDYKVGLAAGLEPFSPVDDYGRYTDEFPLMQGKKVFDANPEIIQLLRDKGLLLYHGELEHSYPHSWRSKKPLIFRATPQWFFKIDFQDLREKSLSAIDGVRWIPSWGITRIRSMVETRPDWCLSRQRNWGVPIPAFTCESCGQTHIDDASIQFFTKMVREKGIEIWYSEETKDLLPPKTKCGKCGNDSFKKGNDILDVWFDSGVSNFSVLGERKDEPPADLYLEGSDQHRGWFQSSLWPSMALRGIPPYKAVLTHGYVLDEKGRAMSKSLGNGIDPTADIIQVYGADILRLWVSSLDFRDDIKVGKESLKIVSEQYRKIRNTFRYLLGNLDGHTPEQNLPFEELEELDRFYLSKLAGFVEDAVASYETYQFHQIYQKLILFCTVTLSQDYFDMIRDRMYCDLRDSKSRRSSSTALQYILDSLCILVAPILSFTAEEVWTSNGKKDSVFLQTFPDLKSWKNQSLEDKFESALQAREVVQKALEIARQEGKLGKSLEAALEIVSKSGLSFGELLPKETLELLFVVSQIHEENPGMEVLSSHENEKFSVKVLKPLQGECPRCWRHTEDISKEGDLCGRCKSVVA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURA_BURTA
Sequence: MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVGLIARRLQQQKAPVPPTDQLRAQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQANGMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVDSKITVSDAEVASYIASQRGPNAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDAKKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPKIVQTHVRHILLRVGEGKSESQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGRRDAEGSVQQQMDIARQAIGQRKAEQAYSDWLRELRDSSYVQIKLPVGQ
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: TTCA_VIBVU
Sequence: MTEQIQERTKAQQYNFNKLQKRIRRNTGQAIADFNMIEDGDRIMVCLSGGKDSFTMLDILISLQKSAPISFSLVAVNLDQKQPGFPAHVLPEYLESLGVEYKIVEEDTYSIVQDKIPEGKTTCSLCSRLRRGILYRTAKELGATKIALGHHRDDILETLFLNMFYGGKMKGMPPKLVSDNGEHVVIRPLAYCREKDIIKYSDMAGYPIIPCNLCGSQPNLQRQNIKQMLNDWDKRFPGRIETMFRAMQNVVPSHLADFELFDFKSINKDSGVINGGDIGFDKEEMPVATVEDEDMVQEFDPSLKLDVTNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_EXIS2
Sequence: MNNADRLKRQKSIRNFSIIAHIDHGKSTLADRILEKTGALTSREMKDQTLDAMDLERERGITIKLNAVQLKYTAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPIINKIDLPSADVERVRQEIEDVIGLDASEAVPTSAKAGIGIEEILEQIVAKVPAPTGDPEAPLEALIFDSYYDAYRGVVASIRVVNGTVKVGDKIRMMSTGKDFEVLELAVSTPKPLRQKELTVGDVGTLSASIKTVGDVRVGDTITLAKQPAQEALPGYRKMNPMVYCGLYPIDAARYNDLREALERLQLSDAALEFEPETSQALGFGFRCGFLGMLHMEIIQERIEREFNIDMITTAPSVIYHVTTTAGEVLHVDNPSKMPEQQKVEFIEEPYVKAAVMTPNDYVGAIMELCQKKRGTFIDMEYIDTTRVKITYELPLSEIVYDFFDQLKSSTKGYASLDYELIGYQQSRLVKMDILLNNENVDALSFIVHRDFAYERGKVIVDKLKELIPRMQFEVPIQAAVGTKIVARSTIKALRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKMVGSVEVPQEAFMSVLSMDED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UREG2_BRASB
Sequence: MSRLALTRADEPMTAARVGIGGPVGSGKTALVERLIPALQTRGIDIAVITNDLVTAEDAERVRRSGLIDPERVSAVEAGACPHTVIREDPTLNIEAADELERRFPGVELILLESGGDNLASTFSRDLTDFWMFVIDVAGGDDIPRKRGPGVIRADLLVINKVDLAPHVGVDLGRMQREATEVRGGRPVLLTNCRRGEGIEAIVDLLEREVLFRK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_TOLAT
Sequence: MKQYLDLCQRIIDEGVWIENQRTNKRCLTVINADLVYDVRNNQFPIITTRKSFWKAAIAELLGYIRGYDNAADFRALGTKSWDANANENEAWLKNPARKGLDDMGRVYGVQGRHWKTHDGTELDQLGKIVANLSKGIDDRGEILTFHNPGEFNLGCLRPCMHTHTFSLLGDTLYLTSYQRSCDVPLGLNFNQIQVFTLLALMAQITGNKPGLAYHKIVNAHIYEDQIELMRDVQLKRKPYPSPKLEINPDIKSLKDLETWVTLDDFNVTGYQHHDAIKYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA180_HUMAN
Sequence: MLGPNAQVTVVVAQPGPDHLDHLLLDTQHCQHSSCGSAACTQLTWVPCLGGSHKASIKMSAQAVVSTEAPWERPCFQAHLGCLQNSVLCSCRMEGFSLFLAMLWGGVGELPSDPRGHLQFLAT
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01555.
Protein: PHNC_STAAN
Sequence: MSQIEFKNVSKVYPNGHVGLKNINLNIEKGEFAVIVGLSGAGKSTLLRSVNRLHDITSGEIFIQGKSITKAHGKALLEMRRNIGMIFQHFNLVKRSSVLRNVLSGRVGYHPTWKMVLGLFPKEDKIKAMDALERVNILDKYNQRSDELSGGQQQRISIARALCQESEIILADEPVASLDPLTTKQVMDDLRKINQELGITILINLHFVDLAKEYGTRIIGLRDGEVVYDGPASEATDDVFSEIYGRTIKEDEKLGVN
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.