PharMolix/UniProtQA huggingface dataset:
Protein: Y688_GEOTN
Sequence: MLYLHDIWVNWFEGEENGYNVCHFHEWRKDDQIELLDQVPLLKVSPALFHYIENSLSDLPKPLLDDVYQKAYIRKNHERIQLDYCFIVTDGVGILAVDTIGYHIPIRKSRLIPRQEQLVYEMAAEAEEQKYPLPKYEKEYHILSPAPELMCGLTRKERQLKQLLFMALDQLYSTKNSAEVRYWYTEWAPEKYSDIQKMSFEEAWERLYEETKYGWSERHEQLCENLIKGQPFFEKLWETQQEPKVN
What are the official names of this protein?
UPF0736 protein GTNG_0688.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: PB2_I83A4
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADRRIMEMIPERNEQGQILWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTIHYPKVYKTYFEKVGRLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGLRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEMLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKILFQNWGVEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKTGVDEYSSTERIVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAARGQYSGFVRALFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRIIVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MDH_ACIBS
Sequence: MKQPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLEVPVEKAQQALKGVMMELDDCAFPLLAGMIGTDDPKVAFKDADYALLVGSRPRGPGMERADLLKVNGEIFIGQGQALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALTQVAQKAGVVVADIEKLTVWGNHSPTMYADYRFATANGESLKDKINDPAWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGEYKIVQGLEIDEFSRERINFTLNELEEERAAIADMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: TAL_STUS1
Sequence: MTSKLEQLKQFTTVVADTGDIDAIARLKPVDATTNPSLLLKAAAMPRYAEHLGNAMKQCQGDIGLACDLFAVAVGKQILELIPGRISTEVDARLSFDTQAMVQRGERLIGLYEQAGISRERVLIKIASTWEGIRAAEQLEKAGIQTNLTLLFSFTQAVACAEAGVFLISPFVGRIYDWYKKHEGRDYQGAEDPGVQSVSRIYDYYKTHGYKTVVMGASFRNVGQIESLAGCDRLTISPELLGQLAEASGTLERKLEPGRASEPRISLDEKSFRWGLNEDAMATEKLAEGIRQFARDQEKLEALLTELA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
Protein: PKFF_EMENI
Sequence: MRHTALLPLVSSFIVPALAQIPGQTTVNATVNQGRFGNATYDYVIVGGGTSGLAIAARLAEDPSLSVAVIEAGGYYELDGTVASIIPGLAAGANVGTDATEYSTVDWNFQAQPLTSANDRSLRYNRGKTLGGSSARHYMVYQRGTRGSYDQWAELTGDESWGWDSVFPYFQRSVNVTPANMTGRFPNTTVTYDPSGFNKAGGPLHVTWPNYGSPWSTWIEQGLEAIGILPDTDFNTGTLNGSSWAPITINPLSQKRDSSETSFLQQSLKTTNLTVYLHTMALKIGFDGTTASSVDVRSPVGRFTLSARREIIVSAGALQSPQLLMVSGIGPRETLERHGIPVVKELAGVGQKMWEHPFFGITHQVNLVTATELAINQQALLQALNQYKSQQGPLTSAGFGVLGWEKLPNSTLSDSTNEALATFPSDWPTIEYLSIDGYLNGWHSAADQATGNGQQWGTIAVALVAPLSRGNVTISSSDMDDPPVFDLGFLTHPADREIAVAAMRRIRQAFAAISEITIGDEVVPGADVSTDEELLDFIRESIVPVYHVAGTCAMGREDDPEAVVDPQARVIGVNNLRVVDASIFPTLPPGHPQSTCYMVAEKIADLIKKGN
What is the function of this protein?
Dehydrogenase; part of the gene cluster that mediates the biosynthesis of aspernidine A, a prenylated isoindolinone (PubMed:23706169).  The starting point of the biosynthesis of aspernidin A is the production of orsellinaldehyde by the non-reducing polyketide synthase pkfA (PubMed:22510154).  Hydroxylation, methylation of one of the phenol groups, and prenylation, presumably catalyzed by the prenyltransferase pkfE, would be needed to yield aspernidine D (Probable).  Subsequently, the cytochrome P450 monooxygenase pkfB is responsible for hydroxylation of aspernidine D to yield aspernidine E (PubMed:23706169).  The dehydrogenase pkfF may be responsible for further oxidation of aspernidine E to form a dialdehyde intermediate which is further transformed in a series of steps, some of which are enzyme-mediated, to generate aspernidine A (Probable).  The possibility that additional enzymes outside of the cluster are involved in aspernidine A biosynthesis cannot be excluded (Probable).
What are the official names of this protein?
Dehydrogenase pkfF.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: QUEF_RICCK
Sequence: MPLSASLLGKNSTYKDSYDATLLFKIPRINNRNELGINSNNLPFYGVDIWNTYELSCLNKNGKPWVGVGTFYIPTDSENIVESKSFKLYLNSFNNFVVESIEELERIILQDLSNVTHAKVTGQIFPINTKIEFGLPSGKNIDDLNIECNNYCPPDNSLIEYEDVLVEEEINSNLLKSNCLVTGQPDWGTIVIKYRGKKLKHDSFLKYLISFRNYNEFAEQCAERIFTDINNSINPDFLSIYIVYTRRGGIDICPYRSLDQNYNLPSNKRLIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_DESRM
Sequence: MIDNYNRNINYLRISVTDRCNLRCVYCMPPEGVKQTPHSEILSLEEFARVVDAASDIGIRKIRITGGEPLVRKNIVNLFEKISTNSAIDDISLTTNGVLFAEMASDLKKAGLNRVNFSLDSLNPDTFRDITRMGKFNDVWRSIQKALELELHPVKLNVVAVRGINDHEFADFARLTKEIPIHVRFIELMPIGECNPWAVGNFIAAEEILHGLQQKFGLLDTQVKVTGSGPAKYYCLPNSKGTIGFITAISEHFCAGCNRLRLTANGQLRPCLYGKQEFDLKTPLREGASRQELAKIITKAIRHKPSQHHMEDGWRDRRVMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TF2AA_HUMAN
Sequence: MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with TBP mediates transcriptional activity.
What are the official names of this protein?
Transcription initiation factor IIA subunit 1, General transcription factor IIA subunit 1, TFIIAL, Transcription initiation factor TFIIA 42 kDa subunit, TFIIA-42.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_STRP6
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: OPSD_PETMA
Sequence: MNGTEGENFYIPFSNKTGLARSPFEYPQYYLAEPWKYSVLAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAVANLFMVLFGFTLTMYSSMNGYFVFGPTMCNFEGFFATLGGEMSLWSLVVLAIERYIVICKPMGNFRFGSTHAYMGVAFTWFMALSCAAPPLVGWSRYLPEGMQCSCGPDYYTLNPNFNNESFVIYMFLVHFIIPFIVIFFCYGRLLCTVKEAAAAQQESASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFTHQGSDFGATFMTVPAFFAKTSALYNPIIYILMNKQFRNCMITTLCCGKNPLGDEDSGASTSKTEVSSVSTSQVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: TUSC_VIBCH
Sequence: MNKVAWVFHTPPHGSTAGREGLDAILATSAYSEEQALFFVGEGVLQLVNHQHPESILSRDYISAFKLLDLYDIEARYVCQQSLVSWGLSEQDLLIEVEVVDAQALAQLLHHYDQLLTF
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Protein TusC homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_ZYMMN
Sequence: MKGLIYYMAMNDNNKTPQDPQANNWMKTLLIGGGIIAAMTLAVTFFDGNGGRDHNTTSVAYSEFLNRVDNNGVKDVTIGHDELSGHFTDNSAFKTVAPSDPLLVQRLQSKNVTFRALPEDTVSFWQILLSQFLLPFILFVGLGFLFVRQMQKNGGGGAMGFGKSRARLLTEKQGRVTFKDIAGIEEAREELEEIVDFLKDPTRFSRLGGKIPKGALLVGPPGTGKTLLARAIAGEAGVPFFSISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRHRGAGLGNGNDEREQTLNQLLVEMDGFEANEGIIILAATNRPDVLDPALLRPGRFDRQVIVPRPDIEGRLKILQVHMKKTPLAPDVDVRTIARGTPGFSGADLANIVNEAALLAARKGKRLVAMSEFEEAKDKVMMGAERRSVIMTEEEKRSTAYHEAGHALVSLHIPGCDPLHKVTVIPRGRALGVTWNLPERDQLSINIKQMKARLALCFGGRIAEQLVYGEDSLNTGASNDIQQATDMARAMVTEYGMSPKLGWLRYRENQDEVFLGHSVSRSQNISEDTAKIIDQEVRVLVEEGESRARQVLTEHIDELHRLANALIEYETLSGEEAKRAIAGEKITTIEVKPQVTIPLSGGASGVPKSPPFNGWGNAAPQGA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: SAHH_HAHCH
Sequence: MAQLQSVDNFSDYKVKDISLAAWGRKEIDIAEGEMPALMTLREKYRAQQPLAGARILGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAAAGVPVFAWKGETEEEYVWCIKQTITKDGQPWNANMVLDDGGDLTEILHNEFPQMLDHIHGISEETTTGVHRLLDMMKKGELKVPAVNVNDSVTKSKNDNKYGCRHSLNDAIKRATDHLLAGKKALVIGYGDVGKGSAASLRQEGMIVKISEIDPICAMQACMDGYEVVSPYIDGVNTGAADGVNRDLLGHTDLLVTTTGNVNVCDKYMLQALKSGAVVCNIGHFDNEIDTRFMRDNWEWEEVKPQVHVIYRNKDQNDHLLLLSEGRLVNLGNATGHPSRIMDGSFANQVLAQMYLFERKFADLPADEKPKNLYVRVLPKQLDEEVARYMVQGFGGVITKLTQPQAKYIGVEVEGPYKPTDYKY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_SALTI
Sequence: MSTFYQKPFLKLLDFTASELTALLQLAAKLKADKKNGKEEQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGSSGSQIGHKESIKDTARVLGRMFDGIQYRGYGQEIVETLAEYSGVPVWNGLTDEYHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPKACWPQAALVAECSAMAKKNGGAITLTEDIASGVKGADFIYTDVWVSMGEPKEKWAERIALLRDYQVNSQMMALTGNPQVKFLHCLPAFHDDETTLGKKMAEEYGLHGGMEVTDEVFESAASIAFDEAENRMHTIKAVMVATLSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGN_SALDC
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLLTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: AHPD_METSB
Sequence: MSIDSLKGQLPDFAKDVRLNLGSIANDDSLKEQTKYGLLLACALASRNAEVAAAFDREAASHLTPEARDAARAAATIMGMNNVYYRFVHLASNPVYKTMPAKLRMGVIGSPGVPKTDFELWCLAVSAINGCGMCIDAHEKVLADAGVTQEVIQTAVRFAAIVQSAAIALEAAQLPAFA
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: RS21_DROME
Sequence: MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLSIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF
What is the function of this protein?
May be an associated component of the ribosome rather than a core structural subunit.  May act as a translation initiation factor.  Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva.
What are the official names of this protein?
40S ribosomal protein S21, Overgrown hematopoietic organs at 23B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
Protein: LCPS_PHARH
Sequence: MTALAYYQIHLIYTLPILGLLGLLTSPILTKFDIYKISILVFIAFSATTPWDSWIIRNGAWTYPSAESGQGVFGTFLDVPYEEYAFFVIQTVITGLVYVLATRHLLPSLALPKTRSSALSLALKALIPLPIIYLFTAHPSPSPDPLVTDHYFYMRALSLLITPPTMLLAALSGEYAFDWKSGRAKSTIAAIMIPTVYLIWVDYVAVGQDSWSINDEKIVGWRLGGVLPIEEAMFFLLTNLMIVLGLSACDHTQALYLLHGRTIYGNKKMPSSFPLITPPVLSLFFSSRPYSSQPKRDLELAVKLLEEKSRSFFVASAGFPSEVRERLVGLYAFCRVTDDLIDSPEVSSNPHATIDMVSDFLTLLFGPPLHPSQPDKILSSPLLPPSHPSRPTGMYPLPPPPSLSPAELVQFLTERVPVQYHFAFRLLAKLQGLIPRYPLDELLRGYTTDLIFPLSTEAVQARKTPIETTADLLDYGLCVAGSVAELLVYVSWASAPSQVPATIEEREAVLVASREMGTALQLVNIARDIKGDATEGRFYLPLSFFGLRDESKLAIPTDWTEPRPQDFDKLLSLSPSSTLPSSNASESFRFEWKTYSLPLVAYAEDLAKHSYKGIDRLPTEVQAGMRAACASYLLIGREIKVVWKGDVGERRTVAGWRRVRKVLSVVMSGWEGQ
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).  The cyclase preferentially catalyzes the symmetric cyclization of both ends of the substrate to produce dicyclic carotenoids.  Beta-carotene is further processed to the acidic carotenoid astaxanthin.
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVB_AGRVS
Sequence: MSAQNPVLTPEKRGEDVDSALRPQTLDDFTGQAEARANLKIFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATTRLGLLTTPLRDRFGIPVRLSFYTVEELELIVRRGARLMGLGMTDDGAREIARRARGTPRIAGRLLRRVRDFAEVARAPAVTREIADEALTRLLVDNMGLDQLDTRYLTMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTAIAWKHLGLMPPKDMEAAQFRLTLEDDD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RPIA_SINMW
Sequence: MDARQMKIKAAEAALEHVENGMRLGIGTGSTAEEFVRVLAEKVASGFQISGVPTSERTARLCLELGVPLKSLDELPELDLTIDGADEVDGKLRLIKGGGGALLREKIVASASARMIVIADETKVVDVLGAFKLPIEVNPFGQLATRLAIEKVASRLGLTGDIVVRASGDGPFMTDGGHLILDASFGRIPDADALAVELNAIPGVVEHGLFIEMASMAIIAGPEGARTLKAS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: XDHD_BACSU
Sequence: MIINKPSRVRPDGRGKVTGELKYMTDLSFPGMLYGKVLRSAYPHAEIVSVCTIKAEKMEGVQAVVTHKDVPGLNRFGIVIPDQPVLCEDRVRYVGDAIAAVAAETEEIAEAALELIQVEYKELEVMDSPEKALRPNAQRLHEDGNILHRAFFSNGDVEEGFQASDTVFEETYELPRQMHTYMETEGGVAVPEDDGGFTMYAGTQHGYKDRFQLARIFDIPEEKIRIVSSPMGGSFGGKDELNIQPYAALLALKSGRPVKIHQTRKESVRSGIKRHPMKITIKTGADHSGNLLAHDVKIVADTGAYATLGPAVLDFSVEHAAGPYRIPNIRTEGISVFTNNGVAGEFRGFGGNQITFALETHLDRLSGMLGIDPLELRRKNIRKPHDLGPLEHRIAPTDGAAQVLNAISKSPILKKTSRNCGYLQRGTGAAITMHGGGLGFGRMDAAGGRLSLSSEGKITASFGFEECGQGILAAIEQIVMEELGCAAEDISIVIGDTAKVPKSGSSTASRGTSMVWHAIQRLKKPFLAQLKKRAAEWSGCSAENLIPGAAGLRDKNTKALVVTYKELAEKGPLAEETAFDFPTTPDPVVGGHFLYSFGAAAVEVEVDLLTGDVKLIDCEHAIAAGPVVSPQGYRGQIEGGAAMALGYTLMEEAKMTDGRYAAENLDHYLIPGIKDVPDMKLIAIEDLMKGDVYGPRGVGEIGTIAITPAIVKAVHDAVGCWINKLPISREELLEAIDRKGLKQWT
What is the function of this protein?
Oxidizes hypoxanthine and xanthine to uric acid.
What are the official names of this protein?
Probable xanthine dehydrogenase subunit D, XDHase subunit D.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
Protein: DCD_CAMJ8
Sequence: MGLKADNWIRKMALERKMIEPFCEANIGKGVVSYGLSSYGYDIRVGREFKIFTNVNSTVVDPKNFVEENVVDFEGDVCIVPANSFALARTIEYFKMPDDVLAICLGKSTYARCGIIVNVTPFEPGFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDEKCDTTYKDKKGKYQAQTGITLPRILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SDHL_MYCTU
Sequence: MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGNSGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRRAKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC
What are the official names of this protein?
L-serine dehydratase, SDH, L-serine deaminase, L-SD.
What is the protein family that this protein belongs to?
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Protein: AZOR1_CLOAB
Sequence: MKKLLYISVNTKPEGMSASKTVGREFVDRFVQNYPEYQLIEHDICNEYIPELDHRFLNDNGDIVSGNDYNLLSDNDKKIVDRINDLCNEFVSADVYVIAYPMWSSLFPPRLKMYIDCIVQNGKTIKISEDESSGLLSDKERSVLCIQSSGGVYPKIISWKINHGINYLHDIFRHLGIKKFEKLLVEGVDVQDIGKEKAVEKAFDEIDELIDKMQVRDFVKQ
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS5_BRUA2
Sequence: MAQRERNREERGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KDPB_STAAB
Sequence: MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMILTLILICFPDIFGTSYLSRSYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMWEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGDIPLNIESICMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFAELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTLLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDLA_PSEPK
Sequence: MKQNVIALVFGGRSSEHSVALRSAATIHAALMALGHRVHCVGIDREGNWRYQGEPCQFPGAVDRSAPLISIRPGHRSLSYTTQESGTVEIGIDLLFPALHGRWGEDGTIQGLAAMCGLPCVGSGVLGSAMAMDKDVTKRMVQSAGLVVVPWLAMNSMRPWEELVECLGSSTLFVKPATSGSSIGVSRVSNALEYAAAFAIAAREDTKVLVEAAVCGREIECGVLELEEGLMASVVGEIIKKEGHAYYDYQAKYDSNSVTGLRVPSLLPPDIVARIQALSVQAFRCLELKGYARVDFFLTEEGEIILNEINTLPGFTSASMYPKMFECSGYPPPKLVGALVEYGLSSASKERL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.