PharMolix/UniProtQA huggingface dataset:
Protein: RK16_NEPOL
Sequence: MLSPKRTKFRRPHRGHRRGRALRGNTIAFGDFAIQALESSWVTSRQIEAARRAMTRYARRGGKIWIRIFPDKAITMRPAETRMGSGKGSPEYWVAVVKAQKILFEMKGVPETIARASMRIACFKMPMKTRILQR
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPB_STRPI
Sequence: MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: CRLD_DICDI
Sequence: MSSCSSLSMDDRVKIGYGSIAGASLSIIGSIGTIILIKIRNKKQEKKLLIQRKQQLSINNLNINSGSSSNIITISNSTTSLSSNNLNIQPPSFPSYSPLPTSISLSNNNNNNKNNNQKTKVSHFIINLSIANLLASIFMITIKLMMIHFNDKFIKVLPSTANHSFNALISVCTIGNGVIGFSFISTFFWTLAISMYIYQQFLSSSTINSNNNNNNINNINNNNNNNINNINNSKNNNSINNFNNSNKSNKIIKMLFYFVCWVIPFVLGSILVSGSRLIELNSDLPWCSIDSNIQLISFYFPLIICLLATTFFTILIKYKFSNDKLACSSSSLINLQSKIIQRLILFLIVILVCWVPSLISFFISFFSKNCKQFLWLEIISSTIQSCQGILNFLSYLSIFKKLKLYFKNLKKKFNNNNSNNSNNSNNNNSNNFNGGGIFYSKGKKVNNQNSNNFYFTFSTFDFDNNQIQEK
What is the function of this protein?
Receptor for cAMP.
What are the official names of this protein?
Cyclic AMP receptor-like protein D.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEPA_LATSS
Sequence: MDYAEMLDRQKHIRNFSIIAHIDHGKSTLADRILEMTDTIAKRDMQAQVLDDMELERERGITIKLNAVELHYHAKDGETYIFHLIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQTLANVYLAVDDDLEIVPVINKIDLPSAQPDVVKAEIEEMIGLDASEAVLASAKSGIGIEEILEKLVTDVPAPTGDLEAPLKALIFDSNYDSYRGVVLNIRVVDGTVKVGDKIRLMNSGKEFEVTEVGVMSPKAVKRDFLMVGDVGYITASIKTIQDTRVGDTVTLADNPADAPLDGYRHIQPMVYSGMYPVDNAKFNDLREALEKLQLNDAALEFEPESSQALGFGFRCGFLGLLHMDVVQERLEREFNLDLIMTAPSVDYHVALTDGTEEVIDNPSEMPETSNISEVKEPYVKASIMVPNDYVGAVMELAQRKRGEFVTMDYLDTYRVNVIYNMPLSEIIFDFFDDLKSNTKGYASFDYEVTGYRASDLVKIDILLNGEAVDALSFIVHRDFAFERSRVIVGKLKETIPRQQFEVPIQAAIGNKIIARSTVKAFRKNVLAKCYGGDITRKRKLLEKQKAGKKRMKSVGSVEVPQEAFMSILKMNDEDTKGK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDPB_STAAW
Sequence: MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMILTLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKTFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPNP_BURO0
Sequence: MTSATQFDNVSVVKRANVYFDGKCVSHTVLFPDGTRKTLGVILPCALNFGTDAPELMEVQAGKCRVKLDGSSEWQTYGAGESFSVPGKSRFDIEVLETLDYVCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TRY3_HUMAN
Sequence: MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAARDADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS
What is the function of this protein?
Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors.
What are the official names of this protein?
Trypsin-3, Brain trypsinogen, Mesotrypsin, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_STRSY
Sequence: MNLYDVIKKPVITESSMGQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKTKRVGRYVGRTNKVKKAIITLAADSKAIELFATADAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL24_METAR
Sequence: MCEVCVMVTSSQPRKQRKFRYEAPQHVRSNFINARLSEELSKKYGRTARVIVGDTVKVMRGDAAGTEGKVREIDVKREKVVVEGVSVARADGKEEARPIHPSNLMITKLVLDDPKRVASLERK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: FLHD_SALHS
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMANTLGALTLPQMVKLAETNQLVCHFRFDDHQTITRLTQDSRVDDLQQIHTGIMLSTRLLNEVDDTARKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4G2_MOUSE
Sequence: MESAIAEGGASRFSASSGGGGSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGRSDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTEAVVTDYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSALYALQVHCYNSSFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
What is the function of this protein?
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection.  Cleaved by some caspases and viral proteases.
What are the official names of this protein?
Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Novel APOBEC-1 target 1, Translation repressor NAT1, p97.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: TREA_ECO45
Sequence: MKSPAPSRPQKMALIPACIFLCFAALSVQAEETSVTPQPPDILLGPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPKEGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDNYGHIPNGNRSYYLSRSQPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVPVDLNSLMFKMEKILARASKAIGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDLKSHKVRNQLTAAALFPLYVNAAAKDRASKMATATKTHLLQPGGLNTTSVKSGQQWDAPNGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPLSESTTQPLKQKEAEPTP
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MSCL_XANCB
Sequence: MGMVSEFKQFAMRGNVIDLAVGVVIGAAFGKIVTALVEKIIMPPIGWAIGNVDFSRLAWVLKPAGVDATGKEIPAVVIGYGDFINTVVQFVIIAFAIFLMVKLINRLSQRKPDAPKGPSEEVLLLREIRDSLKNDTLKNPTVP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS18_PELTS
Sequence: MKREKGRRGKKRICNFCVDKAEVVDYKDVQRLKKYITERGKILPRRISGNCAKHQRLLTTAIKRARNIALLPFTAE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y214_TREPA
Sequence: MSKAHRGKGIRGMVGRGRGVCPVTGQTGVKLLYECEIDGKKVKVSKVGRATLQNRKRRLDAQPGA
What are the official names of this protein?
Uncharacterized protein TP_0214.
Protein: UNG_PSEPF
Sequence: MTADDRIKLEPSWKEALRAEFDQPYMTELRTFLQQERAAGKEIYPPGPMIFNALNSTPLDKVKVVILGQDPYHGPGQAHGLCFSVQPGVPAPPSLVNIYKELKRDLNIDIPNHGYLQSWADQGVLMLNTTMTVERANANAHKDKGWQFFTDRIIEVVSQKQPHLVFMLWGAHAQSKQKLIDATKHLVLTSVHPSPLSAYRGFLGCGHFSRTNKFLEQNGEAPIEWRLPPVV
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_ACIF5
Sequence: MNTDALKKMAAEAALRYIQPGMVVGVGTGSTTNFFIEALGAAKIHVDGYVASSIATENRLKAQGLNVLELNATGDIPVYIDGADEADPHFRLIKGGGGALTREKIVASAARLFVCIADDSKDRPMLGKFPLPVEVIPFARSFVARQLVKIGGSPTLRSGITTDNGNVILDVTGLDFSDPLRMEETINAIPGVLDNGIFAHRRADVMLFGSAGGVIERKA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: WUHO_DROPS
Sequence: MATIFFAEPELVIGHGRKVLFLNPGDLQIFKEIELPPDLTTCGLKTVEPVPAPGHPASSSKQQPAALKEATGSVKVEVSIQNVTYSPDRQLLALTTAGQKAVLLYKSRPENAQLLSIRPLARASSALRFCSDGSSVLVTDKTGDCYQYDCVEVDASPRLLLGHLSIVYDVLWSEDQQYIITCDRDDKIRVTNYPATFDIHSYCLGHKEFVSGLAMLTEQHIISASGDKTLRVWNYTCGKELLLHELPAPAVRMLVRQLEPEKTYEVAVLFYDYVDAIGVYRLEQTTTESWSITSTQLVRAEAGTWNICNFALTDDRIYVTGAENERLTLRVYDSRNGERASGLPEGWLKMVLDNLDVAAFMPEDLSVWFKKRFDNVSEYLERKKRRIEEQKQQKCG
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: ENO_CHLTA
Sequence: MFDVVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGASTGIKEALELRDKDPKRYQGKGVLQAISNVEKVLMPALQGFSVFDQITADAIMIDADGTPNKEKLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNLINGGMHATNGLQFQEFMIRPISAPSLTEAVRMGAEVFNALKKILQNRQLATGVGDEGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAASSFYNTQDKTYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQLVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQGYATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIEEEMGPEALFQDSNPFSKA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RS6_LEPIC
Sequence: MRNYELTTITRVSSREVAKSEIQETLKKHSVSVTAEEDWGQRKLWHPIKHEEQGIFHHYKCSADPNAIEKVEKEFLINQNILRSMVVRLHG
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: VSP1_OVOOK
Sequence: VIGGDECNINEHRFLAALYD
What is the function of this protein?
Thrombin-like snake venom serine protease that releases specifically fibrinopeptide B from fibrinogen (FGB) to form fibrin clots.  Shows a preferential cleavage at Arg-|-Gly bonds in fibrinogen beta chains.  Cleaves fibrinogen beta chains preferentially to alpha chains.
What are the official names of this protein?
Thrombin-like enzyme okinaxobin-1, SVTLE, Fibrinogen-clotting enzyme, Okinaxobin I, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLO_ECO57
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSN3_KLULA
Sequence: MYGNQQNNSNPYQMSYYRMNNGQGQGTNRWPQQLSHQEMLAGHSQQILNNNKPAGNQSKPPIVMASNNVFSIGPYRQRKDSSRISVLQKYEIIGYIAAGTYGKVYKAKARDYQNGMNRDNVIILDSPDSVSADSNLDINSINRSTRQQEANDNLTTMDFRKPSHKRFTPPNNSNSTQIRSNSGSETNVRINSSSITNNSRKPSQIQFYAIKKFKTEREGVEHYTGISQSACREMSLCRELDNNHLTKLVEIFLEKKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIMWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFNNMVQTLYTGDKVIVTIWYRAPELILGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMESKKSVLFQANQFQKILEVMGSPDHKIWPNIDSYPEYLQLAKMPKYRDNLTAWYQTAGGKDKTALDILYRLLQYDPIKRIDAIDALDHVYFTNGDPPVCENVFEGLNYKYPPRRIHTNDNDITNVGNDNNQANHSQKQPMHGNNNNKNGNMNGLGVNKRILAAAAAAAAAAAVSGNGNNPTSNTATGGSARKKRK
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase SSN3, Cyclin-dependent kinase 8, KlSRB10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLYA_ANASK
Sequence: MMPTQRLAEADPQIAKLIREETRRQAEGLELIASENFVSPAVLEALGSTLTNKYAEGYPGKRYYGGCEVVDQVEQLAIDRAKQLFGADHANVQPHAGSQANMAAYFALAKPGDTVLAMSLNFGGHLTHGSPVNFSGKLFKIVPYGLRQSDETIDMDEVARLAREHRPRILMVGASAYSRTLHFDRFAEIANEVGAAMVVDMAHIAGLVAAGLHPSPVPHSEIVTTTTHKTLRGPRGGMILCREAHAKTLNSQIFPGIQGGPLEHVIAAKAVAFGEALRPEFKAYQRRIVENAQVLAEGLKSAGLRLVSGGTDNHLMLVDLRPKKLTGKIAEEALGRAGITVNKNMIPWDPEKPMTTSGIRVGTPALTTRGMGSREMTLVAALIGRVLDAPADEQVLARVRGEVKDLCAHFPMYADRV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGK_BACSU
Sequence: MKLDAVTFGESMAMFYANEYGGLHEVSTFSKGLAGAESNVACGLARLGFRMGWMSKVGNDQLGTFILQELKKEGVDVSRVIRSQDENPTGLLLKSKVKEGDPQVTYYRKNSAASTLTTAEYPRDYFQCAGHLHVTGIPPALSAEMKDFTYHVMNDMRNAGKTISFDPNVRPSLWPDQATMVHTINDLAGLADWFFPGIAEGELLTGEKTPEGIADYYLKKGASFVAIKLGKEGAYFKTGTSEGFLEGCRVDRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRGNAIGALQVQAPGDMDGLPTREKLASFLSAQRTVHQKKGDY
What is the function of this protein?
Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
What are the official names of this protein?
2-dehydro-3-deoxygluconokinase, 2-keto-3-deoxygluconokinase, 3-deoxy-2-oxo-D-gluconate kinase, KDG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: TRMD_BURVG
Sequence: MNQATERAVQFDVVTLFPEMFRALTDWGITSRAVKQERFGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLAKPLEAAIGAAKAAQAEQGIASTRVVMMSPQGAPFTHERAVRMAQEPGVVVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDAQSAVQDSFVDGLLDCPHYTRPEEYEGMRVPDVLLGGHHAEIEKWRRQEALRNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKNAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_SHEPW
Sequence: MANSKSAKKRALQSEKRRQHNASRSSMLRTYVKKVIAAINAGDHESATAAFVTAQPIVDRMATKGLIHKNKAARYKSRLNAKIKALAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: AROQ_BACHK
Sequence: MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RNAS1_ONDZI
Sequence: KETSAQKFERQHMDSTGSSSSSPTYCNQMMKRREMTQGYCKPVNTFVHEPLADVQAVCSQENVTCKNGNSNCYKSRSALHITDCRLKGNSKYPNCDYQTSQLQKQVIVACEGSPFVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.