PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_SYNSC
Sequence: MTDAPVSRIRNFCIIAHIDHGKSTLADRLLQDTGTVANRDMQDQFLDNMDLERERGITIKLQAARMNYTAAHGEEYVLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALDNDLEIIPVLNKIDLPGADPDRIKEEVEAIIGLDCDNAIPCSAKTGLGVPEILQAVVDRVPPPKDAVEEPTKALIFDSYYDPYRGVIVYFRVMSGRINCKDKVLLMASKKTYELDEIGIMAPDQKKVDELHAGEVGYLAASIKAVADARVGDTITLVNAPADEALPGYTEAKPMVFCGLFPTEADQYPDLRDALDKLQLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYKVNMIDGSEVMVDNPATLPDPQKRESIEEPYVRMEIYAPNEYNGALMGLCQERRGDYIDMKYITTDRVTLIYELPLAEVVTDFFDQMKTRTQGYASMEYSLIGYRKNQLVRLDVLINGERADALTTIVHQDKAYNVGKALVEKLKELIPRQQFKIPIQASIGSRIIASTSISAIRKDVLAKCYGGDISRKKKLLKKQAKGKKRMKAMGKVDVPQEAFMAVLKLNDGGGS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL1_STRLA
Sequence: MKRSKTLRAADAKVDREKLYAPLEAVRLAKETSTTKFDATVEVAFRLGVDPRKADQMVRGTVNL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RNH_ACIF2
Sequence: MPEKIIELFTDGGCRGNPGIGAWGVWLRLAGQERVLWGFVPETTNNRMELTAALRGLEALKRPSAVRVISDSRYLRDGMTQWLAGWQRRGWRTAGGDAVKNRDIWELLAAVAARHQVQWEWVRGHSGHIENERVDALLNRVMDQYAAGGQAREGEGWL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SALTI
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SYI_MYCGE
Sequence: MDLKKTLLMPKTSFAMQANLSTSEKNFHDFWKDKKVFQKLKKQNKGKQIKILHDGPPYANGSIHVGHALNKILKDFILRSWLYEGYDVVFIPGWDCHGLPIEHAVSKKNPSSYSNLSTVEKRKLCHQFALSQIAVQKEQFQRLGLLNDFQNCYYTIDESFQFKELELFLQAIKKGLIFQDLKPTYWSPISRTSLAEAEIEYKEVNSIALYLTFKVSKSDFLDENANLLVWTTTPWTLPTNQAIAIHPDFDYLLFEYNQQKFVILEKLFEVFTNKLNWTNAIKLKKFKGSNLKNSSYSHCFYNKVLPVLMGIHVVDNEGTGIVHSSPAFGIDDFYLCQKNKIKEVLISIDEKGVFNNLLNDKELENCFYLKANDLIINRLKQNNSFIFSEVISHREPHDWRSKTPVIYRASKQLFIKTKSIKKQLKKQINQVNFLNSKNQLRLKEMLLQRDEWCISRQRVWGLPIPIVYANNKPLLDFSTIQYTIKQLKKHGIDSWFEKDVTCFLKPDKTKKWVKYHKEIDTLDVWFDSGSSYNVLEINKYGSIADLYIEGSDQYRGWFNSSSNCGIIQNDLIPFKSLVSHGFTLDENGNKMSKSLGNIVDPLKICDQYGADILRLWVANTDWQIDNKIGVNILKQVAEQYRRIRNSLLRFILGNINGFNFTSMDDYKFSLEDKIVIHKTNSLVEQIEKFLEKYNFLGCLKVINKFVLWLSSWYFEIIKDTLYCDAKNNPNRLAKQAVLNYIFTQLISFLNIFIPHTAEDAWKNYSFNKKPISVNLFTKPTVFKVANSKNLENIYKTFTSIKNAAFKEIEKLRKEGLISKNNQIELTVGINKKIPKKLKDNLALWLNVNSVNLTNNENEIKVKKTKKTMCERCWNFQTIIKQKLDHNLCSRCFKVC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_BURA4
Sequence: MLARFPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPRWPLLAIFALGTLLMRSAGCAMNDYADRDFDRHVKRTADRPLTSGKIRAWEAVAIAVVLAFISFLLIQPLNTLTKELSVVALFVAGSYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPMLAWVMLIANIFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAVMLCYAATLGIYVWIGVTLGFGLAYWAGWAAAVGCALYHYTLIKDRERMPCFAAFRHNNWLGGVLFAGIAAHYLLAGTAGN
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TCPS_VIBCH
Sequence: MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKSSEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN
What is the function of this protein?
The toxin coregulated pilus (TCP) is essential for successful colonization of the small intestine.
What are the official names of this protein?
Toxin coregulated pilus biosynthesis protein S, TCP pilus biosynthesis protein TcpS.
What are the subcellular locations of this protein?
Periplasm. Secreted.
Protein: IPRA_ECO57
Sequence: MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDTFVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQTITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRIGVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY
What is the function of this protein?
Involved in oxidative stress resistance.
What are the official names of this protein?
Inhibitor of hydrogen peroxide resistance.
What is the protein family that this protein belongs to?
Belongs to the IprA family.
Protein: ARLY_RENSM
Sequence: MTSATNGGSLWGARFAGAPADALAALSKSTHFDWRLARYDLAGSRAHARVLQRAGLLTDVELDGMLTALDGLDADVTSGAFVAAESDEDVHGALERGLIERAGPELGGKLRAGRSRNDQIAAFGRMFLRDHARLVARGVLATIDALLAQATAHHGVAMPGRTHLQHAQPVLLSHHLMAHAWALLRDVQRLQDWDRRAAVSPYGSGALAGSSLGLDPNAVADELGFDSAVWNSIDGTASRDVFAEFSWIAAMIGVDLSRISEEIILWATKEFSFVTLDDAFSTGSSIMPQKKNPDVAELARGKAGRLIGDLTGLLATLKGLPLAYNRDLQEDKEPVFDAADTLELLLPAVSGMIATLDFNTERMEELAPLGFALATDVADWLVRQGVPFRDAHELSGAAVKQAESRGVELWDLSDAEYAAISPQLTPELRTVLSTEGSLASRSAQGGTAPSAVLAQRAAFEAQLAPVRDFAR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 076R_FRG3G
Sequence: MFLSSAVRKDSNGVRHLPSVQRWTPGSPPTRAHGHVSYVAQCATAQCREAVGRTYPGVVKKGLENTDKVRGFI
What are the official names of this protein?
Uncharacterized protein 076R.
Protein: SUB6_TRIEQ
Sequence: MGFITKAIPIVLAALSTVNGAKILEAGPHAETIPNKYIVVMKREVSDEAFSAHTTWLSQNLNRRVMRRSGSSKAMAGMQDKYSLGGIFRAYSGEFDDAMIKDISSHDDVDYIEPDFVVRTSTNGTNLTRQDNVPSWGLARVSSKKAGGTTYYYDSSAGKGVTAYVIDTGIDINHEDFRGRAKWGKNFVDDMDEDCNGHGTHVAGTVGGTKYGLAKGVSLVAVKVLDCEGSGSNSGVIKGMEWAMREASGGGNGTAKAAGKAVMNMSLGGPRSQASNQAAKAISDAGIFMAVAAGNENMDAQHSSPASEPSVCTVAASTEDDGKADFSNYGQLVDVYAPGKDITSLKPGGSTDTLSGTSMASPHVCGLGAYLIGLGKQGGPGLCDTIKEMAHDAIQRPGEGTTSKLIYNGSGK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_HAEIN
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIDTAPGQHGARKPRLSDYGSQLREKQKVRRIYGILERQFRNYYKEANRLKGNTGENLLVLLEGRLDNVVYRMGFATTRAEARQLVSHKAIVVNGRVVNIPSFQVSVNDVVAIREKSKKQARIKASLELAEQREKPTWLEVDSAKMEGVFKRVPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ACCD_RHILW
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLEGNKWVIPASGYHMKMPAKARLADLFDNGDYESLPQPKVAQDPLKFRDSKKYSDRLRDSRLKTEQEDTILAGLGKVQGLKLVAVVHEFNFIGGSLGMAAGEAIVKAFERATSEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDLLKESGQPYIVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGKRVIEQTLREKLPEGFQTSEYLLEHGMVDMVVKRHDIPETLARVLKILTKKPVSVANNMNSGAIALAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SYNSC
Sequence: MSLFDWFADRRKGQYVANVKQEPDEGDGLWSKCPECGQVVYLKDLKLNASVCANCGHHHRIDSAERIALIADPDSFQVLNADLAPVDPLGFKDRRAYADRLRESQASTGLRDGVVTGLCRVEGIPMGLAAMDFRFMGGSMGSVVGEKITRLIEDSTARKLPLLIVCASGGARMQEGMLSLMQMAKISGALERHREAELLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLQEHGFVDTIVPRTQLRSTLANLLRLHGCKPMELTSA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICK28_TRILK
Sequence: MKTIIVFLSLLVLATKFGDANEGVNQEQMKEVIQNEFREDFLNEMAAMSLLQQLEAIESTLLEKEADRNSRQKRCNGNNVPCGPDHPPCCSGLSCEKTFGYGWWYKSPYCVRPSKG
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U16-barytoxin-Tl1d, U16-BATX-Tl1d, Toxin ICK-28.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 06 (ICK-Trit) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KYNU1_NEOFI
Sequence: MGSRLHVQEIQGGPPLPYEDDIRAFCKEYAELLDAHDPLRRFRDEFIVPSKKDLKRKTLFPNDETEETSDEECIYLCGNSLGLQPRSTRKYIEYYLRTWATKGVTGHFVPHDDQLLPPFVNVDEAGAKLMAPIVGALKSEVAVMGTLTANLHLLMASFYRPTRERYKIIIEGKAFPSDHYAVESQIRHHNLDPKDAMVLIESDDLDRPILDTEYILRVIDENAHSTALILLSAIQFYTGQYFDIQRITAHAQSKGILVGWDCAHAAGNVDLRLHDWNVDFAAWCTYKYLNAGPGGMAALFVHERHGRVDMEQAASGKEAFHPRFSGWWGGDKQTRFLMNNHFVPQQGAAGFQLSNPSVLDMNAVVASLELFNQTSMAEIRKKSLNLTGYLEHLLLRDPQTESSEKRPFSIITPSNPAERGAQLSIRLQPGLLDRVLESLDEDAVIIDERKPDVIRVAPAPLYNTYVEVWRFAQLFHLACDKALRGRE
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 1, Biosynthesis of nicotinic acid protein 5-1, L-kynurenine hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_NEIMB
Sequence: MLFPRIIAASAQRKLSVYLKKGGLVAYPTESCYGLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQFEQLQPLLQMPSENLQDMLRKEWPAPKTFLLSAKSCVLPELRGKQRSKLAVRVPAHVGARRLCQALQTPLVSTSCNRAGKRACRTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGETGKRLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_PSEE4
Sequence: MQPYQRDFIRFAIDRGVLRFGEFTLKSGRTSPYFFNAGLFNTGSALAQLGRCYAAAIVDSKIPFDVLFGPAYKGIPLAAATAVALAEQHQLDVPWCFNRKEAKDHGEGGSLVGAPLAGDVLIIDDVITAGTAIREVMQIINAQQAKAAGVLIALNREERGNGELSAIQEVERDFGIPVVSIVSLTQVLEFLADDPQLKQHLPAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LINB_SPHIU
Sequence: MSLGAKPFGEKKFIEIKGRRMAYIDEGTGDPILFQHGNPTSSYLWRNIMPHCAGLGRLIACDLIGMGDSDKLDPSGPERYAYAEHRDYLDALWEALDLGDRVVLVVHDWGSALGFDWARRHRERVQGIAYMEAIAMPIEWADFPEQDRDLFQAFRSQAGEELVLQDNVFVEQVLPGLILRPLSEAEMAAYREPFLAAGEARRPTLSWPRQIPIAGTPADVVAIARDYAGWLSESPIPKLFINAEPGALTTGRMRDFCRTWPNQTEITVAGAHFIQEDSPDEIGAAIAAFVRRLRPA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.  Has a broad substrate specificity since not only monochloroalkanes (C3 to C10) but also dichloroalkanes (> C3), bromoalkanes, and chlorinated aliphatic alcohols are good substrates (PubMed:9293022, PubMed:10100638).  Shows almost no activity with 1,2-dichloroethane, but very high activity with the brominated analog (PubMed:9293022).  Is involved in the degradation of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) as it also catalyzes conversion of 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) to 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) via the intermediate 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (2,4,5-DNOL) (PubMed:7691794).  This degradation pathway allows S. japonicum UT26 to grow on gamma-HCH as the sole source of carbon and energy.
What are the official names of this protein?
Haloalkane dehalogenase, 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase, 1,4-TCDN halidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: SYGB_SALPK
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVVTSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDSAEQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAARLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_STAAN
Sequence: MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT7_SOLTU
Sequence: MADVDDIQPLVCDNGTGMVKAGFAGDDSPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTWKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNXXXXXXXXXXXXXXXXXXXXXXSVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTEHLAKILTERGYSFTTSAEKEIVRDMKEKLAYIALDFEQELDMVKSSSSVEKNFELPDGQVITIGAERFRCPEVLFQPSTIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEFDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-75.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RHMA_SALNS
Sequence: MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALENLDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIESCIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDTMLYTEALDSRLAMFKSVQSVSTAKRSY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.
What are the official names of this protein?
2-keto-3-deoxy-L-rhamnonate aldolase, KDR aldolase, 2-dehydro-3-deoxyrhamnonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
Protein: QUEF_PSEE4
Sequence: MHPAAEHSPLGKSSEYIATYTPSLLFPIPRLAKWAELGVSGDALPWQGVDYWNCFELSWLLPSGKPVVAIGEFAIPCDSPNIIESKSFKLYLNSLNQTKFESVAQLQACLAKDLSAAAGKVVAVKVSTLADVEAQGVTTLPGQCIDALDVTIDNYEQPQPELLRCSTERVVEETVHSHLLKSNCPVTGQPDWGSVVVEYKGRALDHASLLTYLISFRQHADFHEQCVERIYLDLKKLLQPEYLTVYARYVRRGGLDINPYRSTRAISPENLRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_STACT
Sequence: MAKKHVSDLDLKGKVVLERADFNVPLKDGKITNDNRIVQALPTIEYILDQGGRLVLFSHLGKVKEESDKEKLTLRPVAERLSEKLGKDVNFIPHTRGEVLEKAIAELKDGEVLLVENTRFEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHRSHASNVGIASNLESAAGDLMEKEIKFIGGVVNNPDKPVVAILGGAKVSDKIGVIENLLNVADKVLIGGGMAYTFLKAQGYEIGKSLLEADKVDFAKDLLERAGDKIVLPVDAKVAREFSNEAQFTVVTIDQIPADQEALDIGPKTVELFEKELKGAHTVVWNGPMGVFEFENFAQGTVGVCEAIAEMKDATTIIGGGDSAAAAMMLGFEDDFSHISTGGGASLEYLEGKELPGIQSISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_WOLSU
Sequence: MQLLDGKALSLEIEAKVKEEVMILTSSRGVTPGLAVILVGSDPASQAYVNMKAKACKRAGIYSITHEMPESTTESQLLNAISILNNDPNIDGILVQLPLPKHINTAKVLEAIAPHKDVDGFHPQNVGRLTSNLGGFAPATPMGVMRLLQKYGIDPQGKNAVIVGASNIVGKPMASLLLNANATTTLCHIYTKDLASHTQNADILCVGVGKPNLITESMVKKGAVVIDIGINRLEDGSLVGDVDFASVAPKCSYITPVPGGVGPMTIASLLENTLKAAKTRQETPQS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SPB6_MOUSE
Sequence: MDPLQEANGTFALNLLKILGEDSSKNVFLSPMSISSALAMVFMGAKGTTASQMAQALALDKCSGNGGGDVHQGFQSLLTEVNKTGTQYLLRTANRLFGDKTCDLLASFKDSCLKFYEAELEELDFQGATEESRQHINTWVAKKTEDKIKEVLSPGTVNSDTSLVLVNAIYFKGNWEKQFNKEHTREMPFKVSKNEEKPVQMMFKKSTFKMTYIGEIFTKILLLPYVSSELNMIIMLPDEHVELSTVEKEVTYEKFIEWTRLDKMDEEEVEVFLPKFKLEENYNMNDALYKLGMTDAFGGRADFSGMSSKQGLFLSKVVHKAFVEVNEEGTEAAAATAGMMTVRCMRFTPRFCADHPFLFFIHHVKTNGILFCGRFSSP
What is the function of this protein?
Inhibitor of cathepsin G, kallikrein-8 and thrombin.  May play an important role in the inner ear in the protection against leakage of lysosomal content during stress.  May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood.
What are the official names of this protein?
Serpin B6, Placental thrombin inhibitor, Proteinase inhibitor 6, PI-6.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_DESDA
Sequence: MKMYRIRKDDKVMVIAGKDAGKIGKVLKILRKKDRVLVEKTNMVKRHMRPNPYAQQPGGIVEKEMPIHVSNVMVVCSACGKATRVGYKTIESEGKEKKVRFCKKCNEVME
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ARGA_PSEMY
Sequence: MHDYVTWLRHASPYINAHRDRTFVVMLPGEGIAHPNFANIVHDLVLLHSLGVRLVLVHGSRPQIEARLAARGLTPHFHRDLRITDAPTLECVIDAVGQLRIAIEARLSMDMAASPMQGSRLRLTSGNFVTARPIGVLDGVDYHHTGEVRRIDRKGINRQLDERSIVLLSPLGYSPTGEIFNLACEDVATRAAIDLGADKLLLFGAEDGLLDEHGQLVRELRPQQVPAHLARLGSNYQGELLDAAAQACRGGVGRSHIVSYATDGALLSELFTRTGNGTLVAQEQFESLREATIEDVGGLIELISPLEEQGILVRRSREVLEREIEQFSIVEREGLIIACAALYPIADSDCGELACLAVNPDYRHGGRGDELLARIEARARAQGLKTLFVLTTRTAHWFRERGFEPSSVERMPAARASLYNYQRNSKVFEKAL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U496A_ORYSJ
Sequence: MGNSSSSGSHRPPRPASSESALPPAAAAAEELSSYEAACRSDPELRTFDTTLQRRTSRAISTLAVGVEVRSLSLESLREVTGCLLDMNQEVVRVILDCKKDIWKSPELFDLVEDYFESSLHTLDFCTALDKCLKRARDSQLLLHVALQRFDDEEDNDAAAAGQEDAAPSARYARTLHELRQFKAAGDPFTEEFFSAFQAVYRQQLTMLEKLQQRKHRLDKKVRAIKAWRRVSSIIFATTFAAVLICSVVAAAIAAPPVAAALAAAASIPVGSMGKWIDSLLKGYQDALRGQKEVVSAMQVGTFIAIKDLDSIRVLINRVELEISSMIDCVEFAERDEEAVKFGVEEIKKKLEVFMKSVEDLGEQADRCSRDIRRARTVVLQRIIRHPS
What are the official names of this protein?
UPF0496 protein 1.
What is the protein family that this protein belongs to?
Belongs to the UPF0496 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.