PharMolix/UniProtQA huggingface dataset:
Protein: RSMG_GRABC
Sequence: MFHVKQPLINCQIIRTLLPAGSGVSRETGEKLALYESLLTRWTRTVNLVSRNDVEHIRDRHILDSLQLLPLLEPLPGPLIDIGSGGGLPGLVLAIATGRETHLVEADQRKAAFLREAARATESNVTVHACRIEQCNIAPAPVLTARALAPLNVLLGYALRLLSKNGVALFMKGKTAEQELTEAATEWHMRVQLSPSRTHPEASILRIDEISRV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_AROAE
Sequence: MTFLARLFGEKKKTAEIAKNRLSLLIAHERGDGVPKVDFLPALQRELIEVISKYVPVNSDDIKVHLDKQNNYEVLEVNIVLPEQNQGR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DRS1_USTMA
Sequence: MRVQQSKPSAAAKRKAAATSLTTSPQKKRANTTPKRAKDDDFIMTLDSDDDVEDLDAAHVDADHVASDNSEREPEPEAELEPEHSSTPPDGKLTKNQRKRKEKAHLVGKEKIIESLASRSKTNSAAAVKDAMALDKDFEFDIFGDGSAVDYTGAEANGWDMSVTGTRMHKKLNVDDIIEKRRKVLPTLPAPVEEEEENSDEDDQDDDLDDDIKYAEYQDSDDDEDRFGGGNGNIVGQNKDEDQQDAAELDSQEDPLSSDAESASDDDDDNDNDDDDDELQVAEQDEESNSSEDDSDLETEQEKARKAAFFAEDPIATSADSSSKSKSTNDAESSFGAFDLSRPVLRALSSLSFHKPTPIQSRTIPIALAGKDIVAGAVTGSGKTAAFMIPTIERLTWRAKTRTPHEAKSRVLILAPTRELAIQCYSVGKSIAKFTDIRFCLCVGGLSVKSQEAELKLRPEVVIATPGRLIDHVRNSASFTLDDIEILVMDEADRMLEDGFADELNEIVKSCPKGARQTMLFSATMTDDVEQLVRLSLKRPVRLFVDPKRTTAKKLIQEFVRVRGTGTGGVAGADGLSGIQDQPATWISGGRKSEDAQRPALLLSLCTRTFTSQTMIFVRSKKLAHQLKIVFGLLGLSAGELHGDLSQEQRIDALTDFRDGKTDFLLATDLASRGLDIKGVQTVINYDMPGQFEAYLHRVGRTARAGRNGRAVTLVGEADRRMLKLAIKKSSAEQIKHRIIPSAVAAHMCETLERLKPEVDAVLREEKEEKALRIAEMELKKGENMANHADEIFSRPKRTWFQSGSEKTQASALSKAGYQATMDARSSSKQKDKYAGLSRKKRRSKMMRQEIERERKDASGSAGAKTASGGGMDAGIRAAKKAQRPTKLGVAPLKLANKSKGKQSGRNARPSATGGSKTKSSFNRDFSGNKRR
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATPG_CUPPJ
Sequence: MAGTKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQERMRNARPYAEKVRNIAAHLASANPEFKHPFMQEREVKRVGMIVVTTDKGLCGGLNTNVLRAVTNELKTLQGRGVDVQATAIGGKGMQFLSRIGAKVVSNVVQLGDTPHLEKLIGAIKVQLDAFTNGEVDAVYLSYTRFINTMKQEPMVEQLLPLAADKLAQTEEEKRAYSWDYIYEPDAQTVVEDLLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKNVIGELQLDYNKTRQAAITKELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPP2_ACRMI
Sequence: QPKELMQVDLPLVSTQNCSLLYANYDPSTMICAGTRQGGTGACNGDSGGPLVCEFKGKWYLEGVTSWAGVPCASPSKPTVYADVRKLKSWIAAKITGVPVLRVATNCNSVINNTLKSPGYPNSYPINMFCVYRVPIPCDTELVIHFNSFHLENHVFCWYDRLRITDGSNRVIGTYCGQQTGRSVLVNDTVAVLTFKTDRSLNSSGFHLSFSFFRRAVCGIRPTLSGFIVGGTVAPINSWPWQAKLRIAGNFLCGGSLIQPEWVLTAAHCVEGESPSIIKVTLGAHYLSTAQVVGTEQYFDVVQIIQHENYKMPKPFSNDVALLKLSRPAVLRNGVGLVCLSDEQFQRPFNKTTKSCWTTGWGTLFYRGSQPKELMQVDLPLVSTQNCSL
What are the official names of this protein?
CUB and peptidase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARC1B_RAT
Sequence: MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWNKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSAGGSRVAWVSHDSTVCLVDAEKKMAVATLASETLPLLAITFITENSLVAAGHDCFPVLFTYDNAAGTLSFGGRLDVPKQNSQRGLTARERFQNLDKKASSEGGAATGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIR
What is the function of this protein?
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ARPC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: PANC_SALDC
Sequence: MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRADDIQIRDADTLQELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC2M_DROME
Sequence: MIKLFTLKQQKKDGEQKGSQQKKASAAQLRIQKDINELNLPNTCATDFPDPNDLLNFKLIISPDEGFYRDGRFVFNFRVGSNYPHEPPKVKCATQVYHPNIDLDGNVCLNILREDWNPVLNINSIVYGLQFLFLEPNPEDPLNKEAADVLQTNRRQFENNVKKAMRGGCVGETYFECCLLK
What is the function of this protein?
Accepts the ubiquitin-like protein Nedd8 from the Uba3-APP-BP1 E1 complex and catalyzes its covalent attachment to other proteins.  Required for Cul1 and Cul3 neddylation.  Negatively regulates full-length ci stability and hedgehog signaling.
What are the official names of this protein?
Nedd8-conjugating enzyme UbcE2M, Nedd8 carrier protein.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein: WBP4_CHICK
Sequence: MADYWKSQPKKFCDYCKCWIADNRPSIDFHERGKNHKENVAKRISEIRKKSMEKAKEEENMSKEFAAMEEAAMKAYQEDLKRLGIKPDDVGPSSTLNKTQSITAEGKEKKEKKEKKEKKEKKKKTREGTSESPKTEPKEWVQGLSPEGYTYYYNTKTGESQWEKPKGFQGNSKTSHTGSVWVEGVSEDGHTYYYNTQTGVSTWEKPDGFVSSSNDNSQRGKHSEEADSRASESDSEQEDSESEGQSPGTNLKRKGENDEESEKEKSPKAKKLSPYGKWREVKWQEVKWQEEAVDKEKIALASKEASSDESKTDTYGKWKAIKNEEEEEPDEKVDLELPSTEGDSALPPVLDVPEDATVIFKEKTVTSLGDLTEGVPTFKKREFENGKSRNLRQRLDDQ
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome.  May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex.
What are the official names of this protein?
WW domain-binding protein 4, WBP-4.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: RLMD_FRATO
Sequence: MGRSRYHNKLKEGIFEAEITALSHDGRGIAKVDGKTTFIPFTLPGEVVKFEYTFTKAKFDEAKVVEYVKKSLNRVNPPCDHFQICGGCSLQHMSTDAQIEHKQQTLINQLKYIGNGVEPENILPPLRTSNTEGYRNKARLGVRYVSKKGKILVGFRERNGRFLADIDKCIVLNPLVGDKITEISSFIETLSIYQHIAQLEIAIDDTRPAMIVRHLEPFTNEDLEKLRSFAQENNYWIYLQSKGPDTIFRLYPQGDVEPKKLSYQPAAGIDIGFEPNDFTQVNNDINKKMIKRAIELLDISENDSIIDLFCGLGNFTLPISQHAKTVIGVEGEPTMVKRAKETADNNNITNVNFYAANLFESFEDKEWFNNFEYNKMLLDPPRAGAQEVCNNIEKFNVKRIVYVSCDTAALARDAGILVNTKGYKLISAGVMDMFPHTMHVESIAVFEKI
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: DNAK_BIFAA
Sequence: MGRAVGIDLGTTNSCIATLEGGQPTVIVNAEGARTTPSVVAFSKSGEILVGEVAKRQAVTNVDRTISSVKRHMGTDWTVEIDGKKWTPQEISAQVLMKLKRDAEAYLGEPVTDAVITCPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAALAYGLEKGKEDERILVFDLGGGTFDVSLLEIGKDDDGFSTIQVQATNGDNHLGGDDWDQKIIDWLVGEVKNKYGVDLSKDKIALQRLKEAAEQAKKELSSSTSTSISMQYLAMTPDGTPVHLDETLTRAHFEEMTSDLLGRCRTPFNNVLRDAGIGVSDIDHVVLVGGSTRMPAVKELVKELTGGKEANQSVNPDEVVAVGAAVQSGVIKGDRKDVLLIDVTPLSLGIETKGGIMTKLIERNTAIPTKRSEVFSTAEDNQPSVLIQVYQGEREFARDNKPLGTFELTGIAPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSGLPKDEIDRMVKEAEAHEAEDKKRKEDAETRNQAESFAYQTEKLVNDNKDKLSDDVAKEVTDKVNELKEALKGEDIEKIKSAQTELMTSAQKIGQALYAQQGAADAAGAAGAAGAGAAGSASNGSDDDVVDAEVVDDDKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: QUEA_AERS4
Sequence: MQVSDFHFDLPDELIARYPMAERTASRLLQLDGQSGALRHGQFVDVLDQLNPGDLLVFNNTRVIPARMFGQKASGGKLEVLVERILDEHSVLAHVRASKAPKPGTRLILDGGPDGEKVDAEMRARHDALFEIHFLDPRPVLEILEAIGHMPLPPYIDRPDEDADKERYQTVYNQKPGAVAAPTAGLHFDEPLLAKIRAKGVETAFVTLHVGAGTFQPVRVDKIEDHHMHSEYAEVPQEVVDAIAATRARGGRVIAVGTTSVRSLESAAKASLALSKPLAPFFSDTDIFIFPGYQFQVVDAMVTNFHLPESTLIMLVSAFAGYDHVMAAYQAAVAEQYRFFSYGDAMFVTRRRAVA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_ORITB
Sequence: MKEKELVVNTKTNGSKSEDVIISISLVKKLRDATGAAMTSCKQALQEAKGDIEEAIKVLRKTNLAQMSSKLQRKADEGIVALAVDNNKGAIIEIKFETDFVARNERLQKLAMEAAQLALVHDNLTDLKNAKLSSGETLESQISQDIAVIGENIQVSRIRQVKLVDNGIIASYIHNSVAPNLGQIAVLVALEGNVESDKLTKLGKNIAMHIAATNPRFLSSNEVPESVIMQEKEIFTAQARTTGKPEKVIEKMIEGRVSKFLEETVLLEQAFVIDGKTKISEVLSNAAKELGSEIKITGFSCLKAGEVVE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETS_RHIML
Sequence: MQNRVVSCRFTGSTARRATMPEGIRGRSHILFLVPLSRAESVGRLHQVQRFKVNLPVFVGSVAVIALFVGIGVIAPKRAESIFSGMQTAILSGFGWLYLLSVAVFLFSMLFLAFSRYGELKLGPDDSEPEFRYLSWIAMLFAAGMGIGLMYFAVGEPMTHFASPPEAEPLTIAAQREAMSVTFFHWGVHAWAIYSVVGLSLAYFGYRYNLPLTVRSGLYPLLKEGIHGPIGHVVDIFAICGTMFGLATSLGFGILQINSGLNYLLGIPQSIYVQLLLVTVVTAIATISVVTGVEKGVRILSETNLFLAVLLMLFVLVVGPTGTLMRDFVQNIGLYLDSLVLRTFNIYAYEPRPWIDSWTLFYWAWWISWSPFVGMFIARISRGRTVREFVTAVLFVPAMFTFLWMTVFGNTAIYVDTTIANGELARDVKADLSVALFQFFEYLPWPAVTSTLAVLLVSIFFVTSSDSGSLVIDTIASGGETATPALQRIFWCSLSGIVAAVLLSTGGLTALQSATISTALPFSLVMLILVWSLFVGMRADLARTQSPGSLGPRAYPASGVPWQRRLAMTLSTPDRRAVEKFLQASVLPALEAVARELTRRSRPASVGRDAETGALTLTVPAEGHRDFVYGVQMSEHKLPAFTAYDATVADVRYEARTFFSDGSRGYDIMGMADNQIINDVLFQFERYTGFVRSPESSLLATSPEER
What is the function of this protein?
High-affinity Na(+)-coupled glycine betaine and proline betaine transport.  Required for a rapid adaptation to osmotic stress.  Does not transport other trimethylammonium or related molecules, such as choline, carnitine and ectoine.
What are the official names of this protein?
Glycine betaine/proline betaine transporter BetS.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1187_CAMJJ
Sequence: MGRAFEYRRASKEARWDKMSKLFPKLAKAIQVAAKEGGTDPDMNPKLRSAIATAKANNMPKDNIDAAIKRASGKDSADIKNIHYEGKAAHGALVIVECMSDNPTRTVANVKAIFSKNGGEVLQNGSLGFMFTRKAVFHLEKFAGDLEELELDLIDAGLEELEQNEEELVISGDYTAFGELSSAIETKGLVLKKAGLEYIPNNPVSFSEEQLSDIEKLLDKLEDDDDVQAVYTNID
What are the official names of this protein?
Probable transcriptional regulatory protein CJJ81176_1187.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C719E_ARGME
Sequence: MDETIWLIISTVIIVLGIAKFLLGKSSSSSLSTMEWPVGPKKLPIIGNLHQLGGDVFHVVLANLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNISCSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDYLKEETVRLLSRLIFGQDFQDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVKKRVENLIRPHIVSNPPTNTYLYFLKTQDFNEDIIISAILEVYDLGVDSTASTTVWALTFLVREQEIQEKLYREIVNVTGGKRSVKVEDVNKMPYLQAVMKETMRMKPIAPMAIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESLGNIKTMESSLLAFSAGMRICAGMELGKLQLAFGLASLVHEFKWSCSVDGKLPDLSEDHCFILLMKNPLEAKITCRIH
What is the function of this protein?
Methylenedioxy bridge-forming cytochrome P450 involved in the biosynthesis of isoquinoline alkaloids.  Converts (S)-scoulerine into (S)-cheilanthifoline, a precursor of sanguinarine.  Catalyzes an oxidative reaction that does not incorporate oxygen into the product.
What are the official names of this protein?
Cheilanthifoline synthase, CHS, Cytochrome P450 719A14.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MATK_VIGUN
Sequence: MEQYQAYLELRRSRYQDILYPLFFRESIYGLAYAHESFFIENVDYNNKFSLLIVKRLSTRMYQQTHFILFVNDSKKNTFVGYNYHFFSQIILEGFGIVVEILFSLQLFSSSLRGLEIVKSYKNFQSIHSIFPFFEDQLIYLNHKSDIRIPYPIHLEILVQILRYSIKDVSFFHLIRLFFYYYYNWNSLFPPKKWIFTFFSKRNRRIFLFLYNLYVWEYESIFLFLRNKSSQLQLKHFRVFFERIFFYEKIKHLVEVSTKNCSYTFFFFKDTFIHYVRYQGKSILVLKNTPFLINKWKYYFIYLWQCHFDIWAGLETIYINELSQYSFHFLGYFLSIPLNLSVVRSQMLQNSFLIKIVIKKLDTIVPIIPLMRSLAKTKFCNVMGHPISKPVWANLSDFDIIDRFLRICRNFSHYYNGSAKKKSFYQIKYILRFSCIKTLARKHKSTVRIYLKKLSSEKLLEEFFTEEDLFSLIFPRTSFTLRRFYRGRIWYLDILLRNDFVNYL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR18_LAROX
Sequence: MKQTMDKPKRSFRRHLTPIRRHLSPIGSGDRIDYKNMSLISRFISEQGKILSGRVNRLTSKQQRLMTNAIKRARILSLLPFLYNEN
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPE_GRABC
Sequence: MSDPLALAQALLRCPSVTPLDAGAQSVLAEALTAQGFTVTQLPFGDIANFYAKRVGPRSGPHLCFAGHTDVVPPGDAPWSVDAFAGEVHDGVLIGRGACDMKGAIASFVAACAARPDHPGTISLLITGDEEGVATDGTVRVLDWMRQAGEIPDFCVVGEPTNPGRLGEVIKIGRRGSLNATLTVRGRQGHVAYPHRADNPLPRLVAALHALTTTRLDDGMEGFEPSSLQLTTVDVGNPATNVIPEQAQARLNIRFNPLHRGDDLARWLRGIVQDHAPDAVIDIAISGEAFVTDPDRDPRPGASHGIAALRMAIQRITGLSPRLDTGGGTSDARFITHLCPVVEFGLVGATMHQRDEAVAVRDLQDLTGIYEALLDFYLGKDSA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LEXA_MAGMM
Sequence: MTDRKEHKMKPGRRPTEGMTPSQERIMQVIRNAIDRDGLPPTVKEIAEALGMKTPSAHEQVQKLVKKGFIRRTPRKARSIEIVEQSPEEEPVEKKPDVARLVPVPIIGEVAAGIPILAVENHIGELLMDSRTARGPCFALKVKGDSMIDAEIFEGDYVVVRHQALAENGDIVVAILDGEATVKRLYISEETIELRPENRSYQPIVVPPGGDIRILGKVLAVRGHGAANNNE
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y2428_STAA3
Sequence: MIHSKKLTLGICLVLLIILIGGCVIMTKTNGRNAQIKENFNKTLSVYPTKNLDDFYDKEGFRDQEFDKRDKGTWIIYSEMVIEPKGKNMESRGMVLYINRNTRTTKGNFIVTEITEDSKGYSRSKEKKYPVKMENNRIIPTKPIPDDKLKKEIENFKFFVQYGNFKDFKDYKNGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYHIPTKQAPELKLKGSGNLKGSSVGSKDLEFTFVENQEENIYFSDSVEFTPSEDDKS
What are the official names of this protein?
Uncharacterized lipoprotein SAUSA300_2428/SAUSA300_2429.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: THIC_PSESM
Sequence: MSTKPKNAAHLSESAQVDSGSVQPFTRSQKIYVQGSRPDIRVPMREVTLDVTPTDFGGEINAPVTVYDTSGPYTDPNVIIDVRKGLADVRSPWIDSRNDTERLPGLSSHFGQQRLSDAELTALRFAHVRNPRRAKAGANVSQMHYARQGIITAEMEYVAIRENMKLQEARAAGLLTQQHAGHSFGASIPKEITAEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVGGAAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDLQTMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVARGLAEQAERFKQEGSQLYKKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TOM7_HUMAN
Sequence: MVKLSKEAKQRLQQLFKGSQFAIRWGFIPLVIYLGFKRGADPGMPEPTVLSLLWG
What is the function of this protein?
Required for assembly and stability of the TOM complex.  Positive regulator of PRKN translocation to damaged mitochondria.  Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM7 homolog, Translocase of outer membrane 7 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom7 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: NH125_CAEEL
Sequence: MDLVSTSTSPFSCRICNQKAHGNHFGVLTCRACASFFRRAAFSKWSQLKCQKGGCSRNFCKRCRLKKCREMGMDTTKFQYNRDSFRATGQFQLPPPRSLASFVGRPELFLFCDTEAPNAKMLIDVRYLLEEAGRIINQGYETPASGKNQLENLTEGFKYIKVDMNNISSSKYASKDAIISMWEYYFFTVTRWLMYFEGFQKLNSHTQITLIQSVWNVWSRLHKYVATVDYHKANPDTLPTNVVIHNTLVDIENVEFDSTWLSDYPVEHVRRYLSVQHCREFDILGTLRKLNPSELEITYLFAQICFEHAGKRNQGDIMKVTEQFLDSLANDLHDYYVNEMNNSRYFLRLTQLLKINQAIQFSDISPQKQIRNNIIKKEAEKLEKLQKSQFSIKRLSISN
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-125.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_BRADU
Sequence: MQVTETLSEGLKHEFKISVPASDLDAKAGAKLVDLKDKVRINGFRPGKVPVAHLKKVYGRSVMAETIDQTIRDTNTQLFSERGFRLATEPKITMPSEQAEVEELLSGKTDLTYTVAIEVVPSIALADFKTFQVEKPVADVTDADVDEAIKRIADTNRGYAAKADGAKAESGDRVTINFKGTINGEVFEGGTGEGIQVVIGSNTFIPGFEEQLTGIGAGETRTLKVSFPKNYMNDKLAGQPAEFETTATSIEAPQDIAIDDEFAKTLGLESLDKLKEAARERLVAEFAGATRQRVKRALLDRLDEAHRFEAPPSLVDEEFNLMWNSVKAEMDSAGKTFADEDTTEDAAKEEYRKIADRRVRLGLVLSEIGEKNKITVTDDEVGRAVIERARQMPGREKEVWDYYRSNAQALAQLRAPIYEDKVVDFILELANVTEKKVSREDLYKDDEAEKTAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LRPA_BACSU
Sequence: MIDEIDKKILDELSKNSRLTMKKLGEKVHLTAPATASRVVKLIDNGIIKGCSIEVNQVKLGFSIHAFLNIYIEKIHHQPYLAFIETQDNYVINNYKVSGDGCYLLECKFPSNEVLDQFLNDLNKHANYKVSIVIGK
What is the function of this protein?
Negative regulation of glyA transcription and kinB-dependent sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator LrpA.
Protein: EFTU_PSEFS
Sequence: MAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEVFGSAIVDFDKIDSAPEEKARGITINTAHVEYNSLIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIVVYLNKADLVDDAELLELVEMEVRDLLSTYDFPGDDTPIIIGSARMALEGKDDNEMGTTSVRKLVETLDSYIPDPVRVIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVQDPLEIVGLRDTTVTTCTGVEMFRKLLDEGRAGENCGVLLRGTKRDDVERGQVLVKPGSVKPHTKFEAEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGNCELPEGVEMVMPGDNIKMVVTLIKTIAMEDGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_HAEIE
Sequence: MPIRILSPQLANQIAAGEVVERPASVVKELVENSLDAGANKIQIDIENGGANLIRIRDNGCGIPKEELSLALARHATSKIADLDDLEAILSLGFRGEALASISSVSRLTLTSRTEEQTEAWQVYAQGRDMETTIKPASHPVGTTVEVANLFFNTPARRKFLRTDKTEFAHIDEVIRRIALTKFNTAFTLTHNGKIVRQYRPAFDLNQQLKRVAVICGDDFVKNALRIDWKHDDLHLSGWVATPNFSRTQNDLSYCYINGRMVRDKVISHAIRQAYAQYLPTDAYPAFVLFIDLNPHDVDVNVHPTKHEVRFHQQRLIHDFIYEGISYALNNQEQLNWHTEQSAVENHEENTVREPQPNYSIRPNRAAAGQNSFAPQYHEKPQQNQPHFSNTPVLPNHVSTGYRDYRSDAPSKTEQRLYAELLRTLPPTAQKDISNTAQQNISDTAKIISTEIIECSSHLRALSLIENRALLLQQNQDFFLLSLEKLQRLQWQLALQQIQIEQQPLLIPIVFRLTEAQFQAWQQYSDNFKKIGFEFIENQAQLRLTLNKVPNVLRTQNLQKCVMAMLTRDENSSPFLTALCAQLECKTFDALADALNLLSETERLLTQTNRTAFTQLLKPVNWQPLLDEI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.