PharMolix/UniProtQA huggingface dataset:
Protein: SH3G2_HUMAN
Sequence: MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVALPH
What is the function of this protein?
Implicated in synaptic vesicle endocytosis.  May recruit other proteins to membranes with high curvature.  Required for BDNF-dependent dendrite outgrowth.  Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
What are the official names of this protein?
Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Early endosome. Presynapse.
Protein: CCA_SALA4
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDDDGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEYHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREELTKRRIAAVANWKEKRCPNPAS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PCS2_CAMPL
Sequence: MKEVKEALFMNKGEGESSYAQNSSFTETVTSMTMPVLENAVETLFSKDFHLLQALNAVDLGCAAGPTTFTVISTIKKMMEKKCRELNCQTLELQVYLNDLPGNDFNTLFKGLSSKVVGNNCEEVSCYVVGVPGSFHGRLFPRNSLHLVHSCYSVHWLTQAPKGLTSKEGLALNKGKIYISKTSPPVVREAYLSQFHEDFTMFLNSRSQEVVPNGCMVLILRGRLSSDPSDMESCFTWELLAAAIAELVSQGLIDEDKLDTFNVPSYFPSLEEVKDIVERNGSFTIDHMEGFELDSPQMQENDKWVRGEKFATVARASTEPIISNQFGHEIMDKLYEKFTHIVISDLEAKIPKVTSIILVLSKIVG
What is the function of this protein?
No detectable N-methyltransferase activity.
What are the official names of this protein?
Probable 7-methylxanthine methyltransferase PCS2, Theobromine synthase PCS2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: MTAP_CIOIN
Sequence: MMESGDRQNNKIGIIGGSGLESIELFTVKDKVNCNTPYGKPSSSLINGTLNGIECVLLSRHGDSHDIMPTDVNYRANLYALKEAGCSIILATTACGSLQEELKPTDFVVIDQFIDRTTKRHSTFYDGQNVQMKGVCHIPMRNPFCEKLQNVLLSACNVNNVSCHSKGTMVTIEGPRFSTYAESNLFRKWGGSLINMTTVPEVVLANELGMLYAALAMVTDYDCWKEDHASVNVENVMKTMKVNRGNALKVLVSAVEIISKQNLQPDIQLAEKNAKNSVML
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYSNC_PSEAE
Sequence: MSHQSDLISEDILAYLGQHERKELLRFLTCGNVDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKVGTTGDDVDLALLVDGLQAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILIDARYGVQTQTRRHSFIASLLGIRHIVVAINKMDLKDFDQGVFEQIKADYLAFAEKIGLKTSSLHFVPMSALKGDNVVNKSERSPWYAGQSLMEILETVEIAADRNLDDMRFPVQYVNRPNLNFRGFAGTLASGVVRKGDEVVALPSGKGSKVKSIVTFEGELEQAGPGQAVTLTLEDEIDVSRGDMLVHADNRPLVTDGFDAMLVWMAEEPMLPGKKYDIKRATSYVPGSIPSIVHKVDVNTLERTPGSELKLNEIARVKVSLDAPIALDGYEQNRTTGAFIVIDRLTNGTVGAGMIVSAPPAAHGSSAHHGSNAHVTREERAGRFGQQPATVLFSGLSGAGKSTLAYAVERKLFDMGRAVYVLDGQNLRHDLNKGLPQDRAGRTENWLRTAHVAKQFNEAGLISLCAFVAPSAEGREQARALIGAERLITVYVQASPQVCRERDPQGLYAAGEDNIPGESFPYDVPLDADLVIDTQALSVEDGVKQVLDLLRERQAI
What is the function of this protein?
APS kinase catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Bifunctional enzyme CysN/CysC.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: HBOH_BURPS
Sequence: MTAIRGGSRRAPGLALALLGGVLLGACHGDENAQVNALPGFVSGSVRKTAYDGASDDLLTAGLGKTGLGSDTRPGFANPAQPSAAELRRLAIYSNYRALVDITPNGGYGRFWGPNVDLAGNDTLGEGKIAGTEYLAYSDDGSGRKNVTLLVQVPASFDPANPCIVTATASGSRGVYGAIAAAGEWGLKRGCAVAYNDKGGGNGAHEIGTGVVTLIDGTLATASSAGSSSLFTASESSSTLAAFNSAFPNRYAYKHAHSQQNPEQDWGRVTLQAVEFAYWALNEQFGPVVDGTRHGIRYRPGDITTIAASVSNGGGSALAAAEQDTRGWITAVVVGEPQINVRMTPGVTVEQGGAPVPSFGRPLADYATLANLLQPCAAAAVAATGAPYLSALPMGVTQSIRTQRCATLAAAGLVSGADTASQASDALAQLHAAGYLADSDLLQAPMWDSQAMPAIAVTYANAYTRSRVTDNLCNFSFATTNPVTGAVAAPAVSPMTNLFGAGNGVPPTNGINLVFNGASGGVDHRLATPDASFAGAFCLRQLWTANQLGIGTNVDAVRVAANLQHKPAIIVHGRSDALVPVNHASRAYVAQNSATEGRASQLSFYEVTNGQHFDAFLSVPGFDTRFVPVHYYDEQALNLMWNHLKSGAPLPPSQVIRTVPRGGVPGAAPALSTANLPPIVQSPGANAIAVNAGVIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_CHLSY
Sequence: MRITIRDIQQMRDRGERIPMVTAYDYTSAQIADRAGIPLILVGDSLGMVVLGYNSTVPVTLDDMIHHTRAVVRGTQKALVIGDLPFLTYTSPEQAMQSAGRMLQEAGAQAVKLEGGVHIAPTIARLVQAGIPVMGHIGFTPQAVNQIGLRVQGRRAAEAQRLLADALAVQEAGAFAIVLELVPAELAQAITERLRIPTIGIGAGAGCSGQVQVWHDMLGLYSDFLPRHAKRYADLATIIAEALSQYASDVRNGTFPGPEHSSRMDPAELAAALGSQDQATE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_GIRCA
Sequence: MMAAGPRTSLLLAFALLCLPWTQMVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFSNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity).
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB1_PSEAE
Sequence: MSSHRPQHRLSVPDIQRRKGAGSLVALTAYSTPMARLLDPHADLLLVGDSLGMVLYGMPSTLGVSLEMMVAHTLAVMRGSRRACVVADLPFASYQESPRQAFRNAARLLADSGAQAVKLEGGEEMEETVDFLVRRGIPVLAHIGLMPQQVNAMGGFKAQGRDPESAERVRRDGLAMQRGGAFAVVIEGVGEPLARRLSEELAIPCIGIGASPACDGQVLVSEDLLGLSGEQVPRFVERYARLDREIDEAARRFAEDVRERRFPEARHCFAMRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_METMP
Sequence: MNYVKIIEKNKNFIELELVNDDHSLSNLVKEILLAKDGVILASYGVEHPVLDPDTGRYISNPTIMLKTDEKTDAETVLKEALKDIVDLCNKTLEDL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y426_BACAN
Sequence: MIQKQHESKLEVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAETTKIQRGFAEAKVKKVRKASPHRVKAPCPVYEECGGCQLQHLDYKEQLNQKRDIVVQAFEKYMKNSMEEKIRPTLGMENPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDIAHCMIQHKATNEATKVVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKEELPNKEQFIAEVQKQMPAVKSIMQNVNWRKTSVIFGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYNEAKKAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIADARKNAKRHGFTNTKYEAGKAEQWLPKWVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPSSLARDVQALMKSYEVEYVQPVDMFPHTAHVENVVKLTLK
What are the official names of this protein?
Uncharacterized RNA methyltransferase BA_0426/GBAA_0426/BAS0414.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: TRUB_TROW8
Sequence: MLGKVERSEMYILFAMTQVLLVDKISGITSHTAVAKIRHLTGVKKIGHCGTLDPAACGLLIMGCGTATRLIRYMSNLDKRYIATITLGTQTTTDDSEGEIIYSAPKPSLDKITLESIGRAAEKLSGTIKQIPSAYSAIKVSGNRAYNLARQGIIPKLNAREVRVHWKFLGDFENNQVHVQITCSSGTYVRALARDMGKFLGVGGHLSYLKRLSIGPFHLHEIYREINKKEATMSERTPSGNTQGLTDNMAISDNMAISESDKHDCTEPGINCTELGIKDTCTALREVHYTQGDTLSFTRLTALQALSRIYKPIEVSQKQADDLSCGRYISLGIDSNGPVCAVCKENLIAVIQPVSAGLWRPETVLSDNRKLNSNAAQDASGST
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RL2_CHLAD
Sequence: MGIRIYKPTSAGRRNMSVSTFEEITKKRPEPGLIEPLRKKAGRNNQGRITVRHRGGGHKRFYRIIDFKRDKFGIPAKVQAIEYDPNRSARIALLAYVDGEKRYIIAPLGLKVGDTVMSGPNAEIRVGNALPLGAIPLGTQIHNIELEIGRGGVLVRAAGTAAQLMAKEGDYATIRMPSGEVRMIHLRCMATIGQVGNVDHQNIRLGKAGRSRWLGRRPRVRGAAMNPRDHPHGGGEGRAPRGMSTPKTKWGKPARGVKTRHNPRFDRFIIRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PETL_SORBI
Sequence: MLTITSYFGFLLAALTITPALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLCNE_MOUSE
Sequence: MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPAFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDVKCKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERISLILQMCVEAAAEAVKLNCRILGVGISTGGRVNPQEGVVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAAMAERKFGQGKGQENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNVKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRRIH
What is the function of this protein?
Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids.  Required for normal sialylation in hematopoietic cells (By similarity).  Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.  Plays an essential role in early development.
What are the official names of this protein?
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ROK (NagC/XylR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_STAES
Sequence: MSKIIFMGTPDFSTKILEMLIAEHEVIAVVTQPDRPVGRKKVMTPPPVKRVATKHQIPVYQPEKLKDSQELESLLSLESDLIVTAAFGQLLPESLLNAPKLGAINVHASLLPKYRGGAPIHQAIIDGEEETGITIMYMVKKLDAGNIISQQSIRIEEEDNVGTMHDKLSFLGAELLKKTLPSIIDNTNDSIPQDDALATFASNIRREDERVDWNMSAQAIHNHIRGLSPWPVAYTTMNEKNLKLFSAFIVKGKKGNPGTIIETTKHELIIATGSDDAIALTEIQPAGKKRMKVTDYLSGVQESLVGKVLL
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HISM_ECOL6
Sequence: MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFLAIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIALPAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHVKPSSTH
What is the function of this protein?
Part of the histidine permease ABC transporter.  Also part of a lysine/arginine/ornithine transporter.  Probably responsible for the translocation of the substrate across the membrane.  Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity).
What are the official names of this protein?
Histidine transport system permease protein HisM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IHFA_YERP3
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL31_RHOJR
Sequence: MKSGIHPNYVATTVVCGCGNTFETHSTKETGRINVEVCSQCHPFYTGKQKILDTGGRVARFEARYGKRAGKGAAKESAES
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RM02_ACACA
Sequence: MSTLLWKDRPIKNLTFGLKRISGRNNQGRITRYHRGGGVKRMGRLIDYKRYIWNIFGFVHRVEYDPKRNSLIALIVYSNGVMSYILAPEGLLVGDCIFAKENIVLKPGNSTYLQHIPIGLKINSIELSENKGAQFIRAAGSYATIISKFEKIVILKLKSGELRRVHSNCMATIGSISNFQYIYRNFRKAGFYRLKGWLPVVRGVAMNPVDHPHGGGQGKTSGGRPSVTPYGVITKGKPTRKNKSAFIVRRRKS
What are the official names of this protein?
60S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SUS1_YEAS7
Sequence: MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEIVSDSTRETVLKQIREFLEGIVDTQ
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: PANB_ECO81
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_AERS4
Sequence: MPRRRVVGQRKILPDPKFGSELLAKFVNVVMVDGKKSVSEAIVYGALDIIATKSGKDHLAVFEEALDNIRPAVEVKSRRVGGATYQVPVEVRPVRRNALAMRWLVDAARKRGEKSMAQRLAGELLDAADNKGSSVKKREDVHRMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FAD3C_ARATH
Sequence: MANLVLSECGIRPLPRIYTTPRSNFLSNNNKFRPSLSSSSYKTSSSPLSFGLNSRDGFTRNWALNVSTPLTTPIFEESPLEEDNKQRFDPGAPPPFNLADIRAAIPKHCWVKNPWKSLSYVVRDVAIVFALAAGAAYLNNWIVWPLYWLAQGTMFWALFVLGHDCGHGSFSNDPKLNSVVGHLLHSSILVPYHGWRISHRTHHQNHGHVENDESWHPMSEKIYNTLDKPTRFFRFTLPLVMLAYPFYLWARSPGKKGSHYHPDSDLFLPKERKDVLTSTACWTAMAALLVCLNFTIGPIQMLKLYGIPYWINVMWLDFVTYLHHHGHEDKLPWYRGKEWSYLRGGLTTLDRDYGLINNIHHDIGTHVIHHLFPQIPHYHLVEATEAAKPVLGKYYREPDKSGPLPLHLLEILAKSIKEDHYVSDEGEVVYYKADPNLYGEVKVRAD
What is the function of this protein?
Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes.  It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.
What are the official names of this protein?
sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic, Omega-3 fatty acid desaturase 7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: CYB_CRODS
Sequence: MNNIRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIAQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLNSDTDKIPFHPYYTIKDILGALIMITALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIAILAIIPLLHTAKQRSMMFRPLSQCLFWILVADLFTLTWIGGQPVEHPFVVIGQLASVIYFMLILLIMPTTSMIENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL25_THIDA
Sequence: MEIEVIASKRELQGTGASRRLRHAGKVPGIVYGGSTAPVQIELDHNALYHALRKEAFHASVLSLSVDGAKESVLLRDAQWHPYKQQVLHVDFQRVDKDHKIHVKVPLHFLNAEVSPGVKLGGGKPHHIVNELDVQCFPGSLPEFIEVDMGALEVGHSIHANDLVLPAGVELVAHVKQENPAVAVIHAPKGGVEETPAAPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: CLPX_DICTD
Sequence: MSDKNIRCSFCGRTQKEVKKLIAGPGVYICDECVKLAYDIIEEEDSEEIEEENQEFVLPKPHEIKNFLDQYVIGQERAKKILSVAVYNHYKRIFMRSKITEDVEIQKSNVLLIGPTGVGKTLLAETLAKFLKVPFAIADATTLTEAGYVGEDVENILLRLIQNADWDIKRAEKGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLRIVEGTIANVPPQGGRKHPYQEFIQINTKDILFIAGGSFEGIEKIVEKRLDVSNIGFGAQIEPKNRKSLTQILNHIIPEDLIKFGMIPEFVGRFPVVAVLEPLSEEALLKILTEPKNALVKQYKALLSMEGVEINFTDEALKAIVKEAIDKATGARGLRAVMEELMLDLMYELPNLGIKKFTVTPELVYNRNKISQDLLKKLAG
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.