PharMolix/UniProtQA huggingface dataset:
Protein: CLPB_STAAS
Sequence: MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3577_BACAH
Sequence: MASETVSNHQEKALALLQADAEKILRLIKVQMDHLTMPQCPLYEEVLDTQMFGLSREVDFAVRLGLIAEEQGKAMLGELERELSALHEAFTNKQQ
What are the official names of this protein?
UPF0358 protein BALH_3577.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: CLPX_ANAMM
Sequence: MSEARKGAYSCSFCGKLHSEVRKLIAGPRVYICNECVELCSGILQEEGRPARQGGFDLKPPEIKQVLDEYVIGQEHSKKVLSVAVYNHYKRLRNSGVISEVEISKSNVLLIGPTGSGKTLLARTLARVLQVPFAMADATTLTEAGYVGEDVENILLKLLQAANFNVEAAQRGIIYIDEVDKISRKSENASITRDVSGEGVQQALLKVIEGTVSSVPPQGGRKHPHQEFIQINTDNILFIFGGAFDGLEKIIEARNRGSCMGFEANVQKIADKRKDILCYTEPEDLVKFGLIPEFVGRIPVVTSLGRLDEETLYRILVEPKNSLVKQYTKLFEMDNLELKFDNAALLAVAKKAVARNTGARGLRAIMESLLLDFMFNPLGCEGGKVVVDAAMVEDVMMSRNCFESG
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HORN_MOUSE
Sequence: MPKLLESIVTVIDVFYQYATEYGNCDMLSKEEMKELLVTEFHQILKNPDDPDTVDIIMQNLDRDHNHKVDFTEYLLMILKLTKACNKIIGKDYCQASGSKQKNHSHQHQEEQSKKETENKEQKGSISSSAGENDSYSRGSRGSNKSKSKKLRKGKEQSSKQTTKSNSSDHENSEDYEQGQHESGFSNSSGNGRPSSRKASGFPQPGSEQGQSSSSSTKGSGECYSSGNGKHGSSSGGSAVSGSGHSNTYGKQGTGSRHSSSNRRSRSTSRESSGSQEYSSGSSEEPGFTHGSGRKNSSTCGKNGSYSGQSTGRHQQGFGSSHELESGQSITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSSTGKYTSTSGQNYNSTRQGCGQGKSSGSEQYGASSGQSSGCSSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQQFGSGSGRSSGFSQGGSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSRPAGGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCRSGQSTRYGGQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRNQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQPTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRCGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSDQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSG
What is the function of this protein?
Component of the epidermal cornified cell envelopes.
What are the official names of this protein?
Hornerin.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Found in keratohyalin granules of the granular cells of the epidermis.
Protein: Y1662_ALKOO
Sequence: MEERDDIITLLDEEGKEQDFEVIMTLEVEGNEYAILAPVDSDEDEDAYVFKIVYENEDEYSLVTIEDDEEYDNVVAAYETLMDEEM
What are the official names of this protein?
UPF0473 protein Clos_1662.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: NHLC3_PONAB
Sequence: MARFWVCVAGAGFFLAFLILHSRFCGSPVLRNFTFAVSWRTEKILYRLDVGWPKYPEYFTGTTFCVTVDSVNGLVYIGQRGDNIPKILVFTEDGYFLRAWNYTVDTPHGIFAASTLYEQSVWITDVGSGFFGHTVKKYSSFGDLVQVLGTPGKKGTGLNPLQFDNPAELYVEDTGDIYIVDGDGGLNNRLIKLSQDFMILWLHGENGTGPAKFNIPHSVTLDSAGRVWVADRGNKRIQVFDKDTGEWLGAWNNCFTEEGPSSVRFTPDGKYLIVAQLNLSRLSFVTAPPVGSIGECSVISTIQLADQVLPHLLEVDRKTGAVYVAEIGAKQVQKYVPLNSYVPSFGS
What are the official names of this protein?
NHL repeat-containing protein 3.
What are the subcellular locations of this protein?
Secreted.
Protein: RBP17_MOUSE
Sequence: MALHFQSLAELEVLCTHLYVGTDLTERIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVTRINPLPIEQRIDIRNYILNYVASQPKLAPFVIQALIQVIAKLTKLGWFEVQKDEFVFREIIADVKKFLQGTVEHCIIGVIILCELTQEMNLVDYSRPSAKHRKIATSFRDTSLKDILVLACSLLKQVLAKPLNLQDQDQQSLVMQVLKLVLSCLNFDFLGSSADESADDLCTVQIPTTWRTIFLEPETLDLFFNLYHSLPPLLSQLALSCLVQFASTRRSLFSSPERAKYLGNLIKGVKRILENPQGLSDPGNYHEFCRFLARLKTNYQLGELVLVKEYAEVIGLIANFTITSLQHWEFAPNSVHYLLTLWQRMVASVPFVKSAEPHLLDTYAPEITKAFITSRLESVAIVVRDNLEDPLDDTATVFQQLEQLCTVSRCEYEKTCTLLVQLFDQNAQNYQKLLHAAPGLAVDMAIQEGRLAWLIYLVGTVVGGRLTYTSTDEHDAMDGELSCRVFQLISLMDTRLPHCTNEKIELAVLWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRCEPVISRTLQFLSDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISETYNVGDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSFETVLQIFNNNFKQEEVKRMLIGLARDLRGIAFALNTKTSYTMLFDWIYPAYLPVLQRAIERWYGEPACTTPILKLLAELMQNRSQRLNFDVSSPNGILLFREASKMICTYGNQILSLGSLSKDKIYPMKLKGISICYSALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFITNLEPPVLLYVLTSLSEGLTTLDTVVSSSCCTSLDYMVTYLFKHIAKEGKKPLRSREAMQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLGQCFRNLMEGVEQNLSVKNRDRFTQNLSVFRRDVAEALRSDGHTDLSSLDMMS
What is the function of this protein?
May function as a nuclear transport receptor.
What are the official names of this protein?
Ran-binding protein 17.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nuclear pore complex.
Protein: NOCR_AGRT7
Sequence: MIQSRQLEAFRPVMLTGGMTSAANLVRITQPAISRLIRDLEEEIGISLFERTGNRLRPTREAGILFKEVSRHFNGIQHIDKVAAELKKSHMGSLRVACYTAPALSFMSGVIQTFIADRPDVSVYLDTVPSQTVLELVSLQHYDLGISILAGDYPGLTTEPVPSFRAVCLLPPGHRLEDKETVHATDLEGESLICLSPVSLLRMQTDAALDSCGVHCNRRIESSLALNLCDLVSRGMGVGIVDPFTADYYSANPVIQRSFDPVVPYHFAIVLPTDSPPPRLVSEFRAALLDALKALPYETI
What is the function of this protein?
Positive regulatory protein for the noc operon involved in nopaline catabolism and uptake.
What are the official names of this protein?
Regulatory protein NocR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: HMUT_YERPE
Sequence: MRLRLLSLPFILSLCAPLLPLNTLAAERIVTIGGDVTEIAYALGAGDEIVARDSTSQQPQAAQKLPDVGYMRTLNAEGILAMKPTMLLVSELAQPSLVLTQIASSGVNVVTVPGQTTPESVAMKINAVATALHQTEKGQKLIEDYQQRLAAVNKTPLPVKVLFVMSHGGLTPMAAGQNTAADAMIRAAGGSNAMQGFSRYRPLSQEGVIASAPDLLLITTDGVKALGSSENIWKLPGMALTPAGKHKRLLVVDDMALLGFGLETPQVLAQLREKMEQMQ
What is the function of this protein?
Part of the binding-protein-dependent transport system for hemin.
What are the official names of this protein?
Hemin-binding periplasmic protein HmuT.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1446_BACC4
Sequence: MARIGVENSLTDVQQALQQQGHEVVTLNSEQDAQGCDCCVVTGQDSNVMGIADTSIKGSVITAHGLTTDEICQQVESRT
What are the official names of this protein?
UPF0180 protein BCB4264_A1446.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: TRPA1_DROME
Sequence: MTSGDKETPKREDFASALRFLMGGCAREPEMTAMAPLNLPKKWARILRMSSTPKIPIVDYLEAAESGNLDDFKRLFMADNSRIALKDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLHRDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFAFLQCPFMFAKIDEKTGESITTASPIPLPALNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAGDNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLPHVWLQRVDKMELIEYPNETKCKLGFCDFILRKWFSNPFTEDSSMDVISFDNNDDYINAELERQRRKLRDISRMLEQQHHLVRLIVQKMEIKTEADDVDEGISPNELRSVVGLRSAGGNRWNSPRVRNKLRAALSFNKSM
What is the function of this protein?
Essential for thermotaxis by sensing environmental temperature.  Receptor-activated non-selective cation channel involved in detection of sensations such as temperature.  Involved in heat nociception by being activated by warm temperature of about 24-29 degrees Celsius.
What are the official names of this protein?
Transient receptor potential cation channel subfamily A member 1, dTRPA1, Ankyrin-like with transmembrane domains protein 1, dANKTM1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS4_CALBD
Sequence: MSKYIGPDCRLCRREGMKLFLKGDRCYTEKCAFARRPYPPGQHGQERKKLSEYGMQLREKQKVKRIYGVLETQFRRYFEMAEKMKGIAGENLLSLLERRLDNVVYRLGFASSRGEARLLVSHAHFKVNGRTVNIPSYLVKVGDVIEVDERSKSKTRFVEIKEKYAKKPSPKWLEKDAENLVGKVIALPTREDIDMPIREHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: O2T35_HUMAN
Sequence: MGMEGLLQNSTNFVLTGLITHPAFPGLLFAVVFSIFVVAITANLVMILLIHMDSRLHTPMYFLLSQLSIMDTIYICITVPKMLQDLLSKDKTISFLGCAVQIFYLTLIGGEFFLLGLMAYDRYVAVCNPLRYPLLMNRRVCLFMVVGSWVGGSLDGFMLTPVTMSFPFCRSREINHFFCEIPAVLKLSCTDTSLYETLMYACCVLMLLIPLSVISVSYTHILLTVHRMNSAEGRRKAFATCSSHIMVVSVFYGAAFYTNVLPHSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNKDVAAALRKVLGRCGSSQSIRVATVIRKG
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2T35, Olfactory receptor OR1-66.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGFB1_CYPCA
Sequence: MRVESLLLALQCLLGFVHYSGALSTCSPLDLELIKRKRIEAIRGQILSKLRLSKEPEVDEEKESQNIPAELISVYNSTVELNEEQAAPPEQPKEDPVEEEYYAKEVHKFTIKLMEKNPDKFLWFNITDISQTLGLNRIISQVELRLLITTFPDGSEQRLELYQVIGNKSRYLESRFIPNQRKWLSFDVTQTLKDWLQRSEAEQGFQLKMADNCDPQKTFQLKIPGLVLVRGDTETLAVNMPRPHILVMSLPLDGNNSSKSRRKRQTETDQVCTDKSDGCCVRSLYIDFRKDLGWKWIHEPSGYYANYCTGSCSFVWTSENKYSQVLALYKHHNPGASAQPCRVPQVLNPLPIFYYVGRQHKVEQLSNMIVKTCKCC
What is the function of this protein?
Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity).  Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix.  At the same time, LAP chain interacts with 'milieu molecules', such as ltbp1, lrrc32/garp and lrrc33/nrros that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus.  TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1.  Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (tgfbr1 and tgfbr2), which transduce signal (By similarity).  While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'.  Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation.  Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner (By similarity).  Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types (By similarity).
What are the official names of this protein?
Transforming growth factor beta-1 proprotein.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Transforming growth factor beta-1]: Secreted.
Protein: DCAM2_MUSSP
Sequence: MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNVIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
What is the function of this protein?
Essential for biosynthesis of the polyamines spermidine and spermine.  Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 2, AdoMetDC 2, SAMDC 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: 3S1A2_NAJSP
Sequence: MKTLLLTLLVVTIVCLDLGYTLECHNQQSSQAPTTTGCSGGETNCYKKSWRDHRGYRIERGCGCPSVKKGIEINCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Alpha-neurotoxin NTX-2, NTX2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSG_STRPQ
Sequence: MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLMLNMFGSETVAEVELYQIAEL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RBFA_STRPJ
Sequence: MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGDLSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEYGNKIDEMLRNLDKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_CAMC1
Sequence: MIVTRFAPSPTGYLHIGGLRTALYNYLYARANNGKFLLRIEDTDLKRNSEEATQAIKEAFAWCKLDHDGEVTYQSKRFDLYKEYVKKLLDEGKAYKCYMSKEELEELRASQEARKERPKYDNRYRDFTGTPPAGIEPVIRIKAPLSGEIVIHDGIKGEVKFKVEDILDDFIIARSDGTPTYNFTVVIDDALMGVTDVIRGDDHLSNTPKQIVLYEALGFKVPKFYHVAMINGEDGKKLSKRHGATDVMEYKKMGYLPEALLNFLVRLGWSHGDDEIFTIEDMLKYFNPNDINKSSSTYNAQKLDWLNSHYIKTLPYERLAHDMLEFGVDFKALVKGELLLNSLRERSKTLIEMANSANAIINAPKSYDEKAWAKFINENSKEILAKFAQILDRDLDAKGYEELTNKFLEQNGLKLKDLAQALRIALTGSSVSPSIFEVLEVVGSNEIKNRIQNLLKEEK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_TREPS
Sequence: MAVTKKRKEKKNVYEGNVYIQATFNNTIITVTDLQGNALSWASSGGLGFNGAKKSTPFAAQTVAEAAVQKAQQCGLREVHVFVKGPGIGRESAIRMLGTMGLRVRSIRDITPIPHNGCRPRKTRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: VTM2B_MOUSE
Sequence: MEQRNRLGALGYLLPLLLHSLLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGASSAVSSNNAGAAVRTTSETSHDDKNPPPGSPPAGSGVPEAAAAAASATHTATTTAAAAAASSSASPPSGQAVLLRQRHGSGTGPGYSADPLLSLLLLALHKFLHPLLGH
What are the official names of this protein?
V-set and transmembrane domain-containing protein 2B.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MSS51_YEAST
Sequence: MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNALGLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIPTHHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSLAALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHFIGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFFTFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVLMEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ
What is the function of this protein?
Has a dual role in the assembly of cytochrome oxidase subunit 1 (COX1).  It has a regulative function on COX1 synthesis, acting as a translational activator specific for the COX1 mRNA, and it also binds to newly synthesized COX1 protein.  Together with COX14, may act as a chaperone that binds efficiently unassembled COX1 and prevents it from unproductive aggregation.  When bound to COX1, MSS51 is unable to interact with the COX1 mRNA and translation is halted.  This may be a feedback control that ensures that COX1 is only produced as long as potentially harmful assembly intermediates are not accumulating.
What are the official names of this protein?
Protein MSS51, mitochondrial, Mitochondrial splicing suppressor protein 51.
What is the protein family that this protein belongs to?
Belongs to the MSS51 family.
Protein: YR839_MIMIV
Sequence: MELLEKFISQDINNNFLHYLNFKDNGSKKYITNQLIFLEKLFDIPYGNLFLFTKMFDNKVWEIPTNELSEGLVRLFDRLELTKINELAAGNGLLSARLKYYSEKLNTNLKIKTSDGSSKNFGNHEFTYIKVSESDISDFDKSGPIIISWIHRFFEHELLSYVKKHNNEYIFLIGEHPDSTDYGNNHSMYFHNKMYSFGYQHQIIEFQQISQMDYYCYDKIRNDIYNENKTCVVLYYKTHLHSKVTNIINTLKQNHPKLFGKFLNKNKKYYDQDKILLEISKNKINEYFSYCHDDLCLLLTDRYKKLVESSLMDNDDSDSEISHKTIQLSNIIKMMYCGLTKVNLIRPIISCSISNCNSEQSLSRIVRHNENKPTTIILNSVKNNNSVISHSVDDKLSQRYGKKGTIGFSIKRQEYEQENKYTSPFINGSSIPTRMIIRDITERIFAEIMHIKSNINI
What are the official names of this protein?
Uncharacterized protein R839.
Protein: HIS8_NITSB
Sequence: MRFNETLEKIKTYEAGKPIELVVREFGIEPQNIIKLASNENPYGTSPKVVDAVREIADTMYMYPDDSMFELKSALAKRFEIDQKNIIIGAGSDQVLEFCARAVLNEKSSVLMSKITFAMYEIYALQQGAKIIRSSCYRHDLEEFYDLYKKHHPDIIHICTPNNPTGDALDAEYLYSFLDNVQEPLVIVDGAYMEYAAFKDEKKRIHPQDLIKKYPNVIYLGTFSKAYGLGGMRVGYGIADQSVIGQLYKLRPPFNITTLSLKAATTALEDEGFVQYSIEQNFLQMERFVNFALQNGFEFIDSYTNFITYLLPENRKSKSLSEALLKRGVIVRDLTGYGMNALRITVGTKEQNDRFFEIFKEVLNEY
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: FMT_AGRVS
Sequence: MALRMIFMGTPEFSVPILNALFDAGHQIVAVYSQPPRPAGRRGLDLTKSPVHQQAEKLGLPVLTPLNFKAQDDRDAFAAHQADVAVVVAYGLLLPEAILTGTRLGCYNGHASLLPRWRGAAPIQRAIMAGDVQTGMMVMKMDKGLDTGPVALTRRVTITPDMTAGELHDALSQIGAEAMVEAMAKLEAGDLPLTAQPEDGVVYATKIDKAETRINFSKPATQVHNDIRGLSPFPGAWFEADINGKLERIKVLSSQMAEVTDTANVPGTVLDDALTIACGLGAVRLVRLQKAGGKPLDAAEFLRGTPIGAGTVFASAKAGT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RECO_RICBR
Sequence: MNIKDIGVIIAKKPLKENTFIITVFTKNHGLYSGVAKESSKKSKFIYQEGNVVDFLWQARLHEHIGIAKCELVKSYIGHFIINKAKLYAFNSVISLIKELFHEREEHYNFFSLLINYLDNLAKNFCFHDYINFELALLAEMGYELDFTKCGVSNTTQDLAYLSPKSGRAVSYEVGAPYKDKLLPLPKFLLSGNDKITLEEKRQALNLTSYFFNRYLFHNHRQPEIRQVFVEYILEKDAITA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.