PharMolix/UniProtQA huggingface dataset:
Protein: SYM_SALRD
Sequence: MADPTSSERLLVTAALPYANGPIHIGHLAGAYLPADLFVRYQRLKGEDVAFICGSDEMGVAILMRAIREDRTPEDIIDTYHPQIRDNFERFGMSFDYYGRTSSETHTETTQDFFRVLDENGGFDLKTDEQLYDPEAEMFLADRFVIGTCPVCGFEEAYGDQCEQCGSSLSPTELENPQSTLTDATPEFKETTHWYLPLGELQPQLEEWIGSHPEWKNNVVGQIQSWFDEGLKGRAITRDVLWGVPVPDDVAERHGLEAEGKVIYVWFDAPIGYISATKEWAAEQGEPDAWTDYWQDEDTRLVHFIGKDNIVFHCLMFPSMLMEHGDYVLPDNVPANEFLNLEGEKLSTSRGWAVWLHEYLDDFADERHAPDLLRYALATTLPETKDADFSWEGFQQRVNGELANVFGNFVHRTLTFAQRYFDGTVPPLEDPSEADRVMLDRMAEVPDTVGAAYEEHRTRDAVFETMALARRGNKYFNDTEPWHTHESDPQACANTIHVSLQVCAALSILFEPVLPSAAATLRERIGLENVRTSTPDDDPAGAVGWEDAGAPLLPAGHPIPSGPDPEPLFQKIDDDTIEAQIEKLRDRAAERDTDPSSTTDMDYEALSDNISFDDFTQLDLRAGTVTTAEPVPDADKLLRLEVDLGFEERQILAGVAEQMAPDDVVGLEVVVVANMAPKEMFGFESQGMVLMAEEPDGTFVPVTTEAEDGSVVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAG_ECO8A
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB5_MOUSE
Sequence: MDALRLANSAFAVDLFKQLCERDPAGNILFSPICLSTSLSLAQVGTKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLVKRLYIDKSLNPSTEFISSTKRPYAKELETVDFKDKLEETKGQINSSIKELTDGHFEDILSENSISDQTKILVVNAAYFVGKWMKKFPESETKECPFRISKTDTKPVQMMNLEATFCLGNIDDISCKIIELPFQNKHLSMLIVLPKDVEDESTGLEKIEQQLNPETLLQWTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSDFSGMSETKGVSLSNVIHRVCLEITEDGGESIEVPGSRILQHKDEFNADHPFIYIIRHNKTRNIIFFGKFCSP
What is the function of this protein?
Tumor suppressor.  It blocks the growth, invasion, and metastatic properties of mammary tumors.  As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity (By similarity).
What are the official names of this protein?
Serpin B5, Maspin, Peptidase inhibitor 5, PI-5.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GATA_STAS1
Sequence: MTIRYESVENLINLIKNKEITPSKVVSDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMEGKLFGIPMGIKDNIITEGVETTCASKMLEGFVPIYESTVMNKLRNEQAVLIGKLNMDEFAMGGSTETSYYKKTVNPFDHTAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGIVGLKPTYGRVSRFGLVAFASSLDQIGPLTRTVKDNALVLEAITGVDENDSTSAPVEDADYTSDIGKDIKGLKIALPSEYLGEGVSDEVKASVKEAVETLRGLGATVEEVSLPNTKYGIPSYYVIASSEASSNLSRFDGIRYGYHSPEANSLEELYKMSRSEGFGEEVKRRIFLGTFALSSGYYDAFYKKSQKVRTLIKDDFNRIFENYDVVVGPTTPTTAFNLGDEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETKFNFHNEYEKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PLM4_PLAF7
Sequence: MALTVKEEEFSNTLIKNASAFDRLKLGNLKNLKIQKKLQFLYLILFVLITGVFFFFLIGNFYSHRKLYQVIKNTKHTTIGFKIDRPHDKVLSSVLKNKLSTYVKESFKFFKSGYAQKGYLGSENDSIELDDVANLMFYGEGQIGTNKQPFMFIFDTGSANLWVPSVNCDSIGCSTKHLYDASASKSYEKDGTKVEISYGSGTVRGYFSKDVISLGDLSLPYKFIEVTDADDLEPIYSGSEFDGILGLGWKDLSIGSIDPVVVELKKQNKIDNALFTFYLPVHDKHVGYLTIGGIESDFYEGPLTYEKLNHDLYWQIDLDIHFGKYVMQKANAVVDSGTSTITAPTSFLNKFFRDMNVIKVPFLPLYVTTCDNDDLPTLEFHSRNNKYTLEPEFYMDPLSDIDPALCMLYILPVDIDDNTFILGDPFMRKYFTVFDYEKESVGFAVAKNL
What is the function of this protein?
During the asexual blood stage, catalyzes the cleavage of denatured host hemoglobin (Hb) (By similarity).  Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).
What are the official names of this protein?
Plasmepsin IV, Plasmepsin 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Vacuole lumen. Note=In trophozoites, localizes to the digestive (or food) vacuole, an acidic vacuole where host hemoglobin is digested.
Protein: DLTC_STRMU
Sequence: MDIKSEVLKIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVELENHFDITVPVSEFGRDDWNTANKIIEGITELRNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAP2_KLULA
Sequence: MPTELITYEQNFSSGVDAENDYPPLDSGMGSFQVSELERQGDSHKRSNDEISELRDETLNGREKKLRQSESISRNSTGNAQVEAIPHHSINVDQSDNLLSEQENPTKVYLYDDPHLENDPQQRQEESDANGIMEKLTDDNSMKQVSNAKTSLETAQFLETSNSMELQRTKPHDMNIISPSEPLEQPFYVNAKQYYRILKRRYARAKLEENLKISRERRPYLHESRHKHAMRRPRGQGGRFLTAAEMAEMKRKEEEGTDNDSFLQEHVPKMNVLPQQLPGPVKDNNNEKSDEKPVAKEASN
What is the function of this protein?
Binds to the upstream activation site (UAS) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression.  Recognizes the sequence CCAAT.
What are the official names of this protein?
Transcriptional activator HAP2.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBT_ECO81
Sequence: MQILADLLNTIPAIDSTAMSRAQRHIDGLLKPVGSLGKLEVLAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAEQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTQELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: PANB_PROMP
Sequence: MLPSELVKYKKKSQKIIALTAWDSISGSLAEHSGADIVLVGDSLAMVCLGYKSTLPVTLENMIYHTNAVSRGFSKEIEEQSLLVCDMPFLTYQCGENKAVEYAGKIIKNTYAKAVKVEGADPEVQNVISRLIRMGIPVMGHLGLTPQSYLNLGFKQQGNNSESHEKIKRDALSLEKLGCFSIVLEHIPELLAKEIQTELEIPTIGIGAGKFCDGQVRVTADLLGLNDKQPPFCRPIIDGKKIFGEKLKEWVAAEKLN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2B_SACS2
Sequence: MKLLVVYDVSDDSKRNKLANNLKKLGLERIQRSAFEGDIDSQRVKDLVRVVKLIVDTNTDIVHIIPLGIRDWERRIVIGREGLEEWLV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: SHO1_YEAS6
Sequence: MSISSKIRPTPRKPSRMATDHSFKMKNFYADPFAISSISLAIVSWVIAIGGSISSASTNESFPRFTWWGIVYQFLIICSLMLFYCFDLVDHYRIFITTSIAVAFVYNTNSATNLVYADGPKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPYQNNVYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFENTQPNTSEAVNLHLNTLQQRINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQNEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane.  PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures.  Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress.  Involved in the regulation of the mating pathway.  May be a receptor that feeds into the pseudohyphal growth pathway (By similarity).
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1, Suppressor of SUA8-1 mutation, Synthetic high osmolarity-sensitive protein 1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud. Bud neck. Cell projection. Note=Localizes at the tip of the mating projection during conjugation.
Protein: SURE_CHLAD
Sequence: MYILVTNDDGYQSPGLAALRAVLSEIGEVAVVAPDRNWSAAGHYRKLFDPLRAWEGTLSDGSPALICDGTPADCVALAILGLLDRKPDLVVSGINLGANLGTDLLYSGTVAAAMEGIVFGVPGLAVSQIRPKDGQWDFRAAQVAVRRLVMLIRERGLPPELLLNLNIPAVTPETLRGIKVSRLGRRVYRDELVVRYDPRGRPYYWIDGAEPEDHCEEGTDIAAISEGYASLTPVQMDLTSHRWLEELRRWEWE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PWWP4_HUMAN
Sequence: MDSEYVLCSWKGRLWPAKVLCTRGTSPKTKPEKAISLEVQILAVDEKIKVKSTDVKTPTKFEMEDIAASAAAQTKLGAPLREKMGYRGTLRVALEILKERTNLGGGRKPHELESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGKRENPSSPTVPSESKRALRDDRSQEPTAIAPTPGALPGDRSGAPRAIAPTPGAMLSGRSRARRAIAPTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPKPGSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIALTPGVLCGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAARTAVVRTPGALGRDRSRARSAIASTPGTLQGNRSSVSKAIAPTPGALRGDRSAARTAFVPTPGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGALRGYKSWARRAIAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRSWTRRAIAPTPGTLSSYRSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRSPVRRAIAPTPGTLSGYRSRARTAIAPTPGTLRGYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIAPTPGALRCDRSRELTAIDPTPGALCSDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDRSQAGRAIAPTPSALFRVGSRVGTGIALPAGALHRDRSPVRRAVAPTPGTLHCDGSRKCTATGSTPGALPGDRSGVSKATAPAPGALCSERSRARRSIAPTPCLLCGDRSWVGMGIAPTPGALLGGKSRKCRAIAITPGALRGGRSQKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTSIIPSPGALHGDGPPAHMAFPSTPGTLHGDASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWKRKAIASTPGALHGNRSDRSRKCKAIASTPGTLHVERSPALRAIVPTPGTLGRDSSPGRTSIIPSPGALHGDRSPAHLDIASTPGALHGDSSQAHTAIAPTPGTMRGDSSTARMAIAPSAGALRGDRSWKRKAIASTPGALRGNRSDRSRKRKAIASTPGALLGNRSDRSRKHKAIAPTPGAPRIDRSPACRAIAPTPGALGDDSSTAIAPTPGTPRGDSSPANTAIASTPGALHGDTSQTHKAIAPTPGDLGGGSSSAHKAITPSPGALHGDRSPAHTAIASTPGALHGDSSQVHTTIAPTPGALRDDKSWKRKAIAPTPGTLHCDSSRTCTAFAPTPGALHADRSPAHQDITLTSGALHCDSSRESRAVAPILGALHRVGSQAHKAIASTPGPLRGDSSPFHTAIAPMPGALHGTRSWKREAISQTPFVTLCGDSSGERMAIAPTPGALHSDRSQTHTAIDPTPSVLRSDSSPACMAIDPTPGALGRDRSQALMAIAPTPVGMQAHVLQSPRACQDSLTLSRHVCEKKGKKRANASTLMSLPPTVTEEGASLPPGLTSPAPPALKEETQDSRPKKALAASPESSPFSGNIQDPGEGAWKPGWAGMAASSGSRQHRLPSSLRLANRKRKRPGPDFQRRPQGPQTPGDAKLANPVTTIQRAGGKQDGQPPSLAFPQEPHPIERGTMVWFKFQDHPFWPAVVKSVSNTDKTARVLLLEANLHHGKRGIQVPLRRLKHLDCKEKEKLLKRAQKAYKQSVNWCFSLISHYREGLVRGSFRGSFLDYYAADISYPIRRAIQEGDLQIDFPKVNYGDLEDWEEETSLGGKRPCKKILPDRMRASWDRDNQKLVDFIVRRKGADPHLLDILQGRKQSRWLTAFLKPHRDLHCIETYLEDDDQLEVVAKHLQEIYKQIDKARLTLIRDDKVNFVLEVLLPEAMICTIAALDGLDYKAAEEKYLRGPPVHYREKELFDRNILKKARREPATTHTAN
What are the official names of this protein?
PWWP domain-containing DNA repair factor 4.
What is the protein family that this protein belongs to?
Belongs to the PWWP3A family.
Protein: Y4TS_SINFN
Sequence: MSDALLKVESLTKHYPIEAGWFKTNVPVVRAVEDVSFTVQAGETLCVVGESGCGKSTLARLLMRLIDPTSGRVLVEGTDIAGLRKNELRAWRRRMQMVFQDPYSSLNPRLTAGQIITEPVENFECLSRRQRQELATDLLRKVGMSPEMASRYPSEMSGGQRQRLGIARALALKPSLIIADEAVSALDVSVQAQILNLLMDLQQETGIALIFISHDLAVVEHIGHRVAVMYLGRIVELSPRDALFAKPVHPYTEALIAAAPVPDPARARLEVPLEGEVPSPVNPPSGCAFHPRCPLAVDRCRAEVPPLVPMPDGRAVACHVRAPAAAAHISPSALASLALPKTVQPGGTILARR
What is the function of this protein?
Probably part of a binding-protein-dependent transport system y4tOPQRS for a peptide.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable peptide ABC transporter ATP-binding protein y4tS.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UL64_HCMVA
Sequence: GRSLTYPGSIQTDKKSVQRRGLFFFSNGKSESYTFLVVTASFLVVMAVVVNIYLQIQEMRKKKEDKSNGIISDHIYGGISGHHCVSKDDLYNREGYGFKG
What are the official names of this protein?
Uncharacterized protein UL64.
Protein: RFCL_SULIY
Sequence: MIQWFLKYRPRSLKDVENQDGAKKELQEWIESWLNGKPNAKAVLLHGPPGVGKTTLAEALAHDYNLELLEMNASDSRKLQDIKGVAEKASVYGSIFGTRGKLILLDEVDGINVREDTGAIQGILELIEKTKYPIIMTANDPWNPALRELRNKTKMVGLNKLGKYPLRRLLKKICQAEKIICDDEALNYIIDTSEGDARYAINMLQGIGEGYGKVTLDLVEAMARRKERELDPFETLRDIFWARYAWQAKNAATSAQIDYDMLIRWISENIPIQYDNIEDVWRAFDALSRASIFLKRAKGGDWDLLSYAYDLMSSGVAAAEIEKKKPNWKPKWKKYQFPSYIQLLSKSKDIRDTRDEIIKKLAIHSSFNKTLNDTYPFFLIFYKKYDKRLSLNTKEKEYLNSASKS
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: MORN5_BOVIN
Sequence: MEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADDDEHEWIVRTCRKGWDETMGPEPKS
What are the official names of this protein?
MORN repeat-containing protein 5.
Protein: Y673_MYCPN
Sequence: MQFRVGLGKKKYRIKPRAEQKNKFWIGGVEIEDSKYIYDHDASDDASDVIQLAVADALFGATALGDGQIVFNKEKTQIPLKGNPRKEAPRILARTYNFIRKNWYINNIDITLEIPSQQKMDDYKHAIFDFICTALRITELTINLKVREPLNPNEISCLAVVLVERQRLK
What are the official names of this protein?
Uncharacterized protein MG459 homolog.
Protein: RNH_ALIF1
Sequence: MITEIMKQVEIFTDGSCLGNPGPGGYGIVMRYKGTEKTFSEGFNKTTNNRMEMLAAVVALRKLKEPCSVILTTDSQYVRQGITQWIHGWKKRDWKKADKKPVVNADLWKQLDAESERHKIDWRWVKGHAGHRENEMCDELARTAAENPTQDDTGYPG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7A_THEON
Sequence: MAKPSYVKFEVPAELAEKALEAVELARDTGRIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVPAASVAIIEPGKGRELVEEIAMKVRELMK
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAG3_MOUSE
Sequence: MPTLWSPSTQHHGSSSGSESSPLQKSVRRAQMALSPCSSSILPCDDRDSQGTAEWDSPSTNEDSDFEDSLRRNVKKRAAKQPPKAVPAAKHRKKQSRIVSSGNGKNESVPSTNYLFDAVKAARSCMQSLVDEWLDNYKQDENAGFLELINFFIRACGCKSTVTPEMFKTMSNSEIIQHLTEEFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVYQCQYSLLYDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEDIEGMMNAIFRGVFVHRYRDILPEIRAICIEEIGYWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQELSLRMELFTNRFKDRMVSMVMDRECEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSDRERRRSPQAQKTFIYLLLAFFMESEHHNHAAYLVDSLWDCAGSYLKDWESLTNLLLQKDQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKSLTAKERKLQAYDKMKLAEHLIPLLPQLLAKFSADAENVAPLLQLLSYFDLSIYCTQRLEKHLELLLQQLQEVVVKHVEPEVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDFLTDRFQQELDDLMQSSFLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTGEVPHQVILPALTLVYFSILWTVTHISESTSHKQLMSLKKRMVAFCELCQSCLSDVDPEIQEQAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGNGQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQEQGPQGLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSHEPPNLAFLELLSEFSPRLFHQDKRLLLSYLEKCLQRVSKAPNHPWGPVTTYCHSLHPLEITAEASPRGPPHSKKRCVEGPCRPQEEESSSQEESLQLNSGPTTPTLTSTAVKRKQSLRTVGKKQKGRPGPGPGPGPELICSQQLLGTQRLKMSSAPCFQIRCDPSGSGLGKQLTRLSLMEEDEEEELRLLDEEWQRGDKMLHSPSSPSEHGLDLLDTTELNMEDF
What is the function of this protein?
Meiosis specific component of cohesin complex.  The cohesin complex is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
What are the official names of this protein?
Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3.
What is the protein family that this protein belongs to?
Belongs to the SCC3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation.
Protein: SLRP_SALTY
Sequence: MFNITNIQSTARHQSISNEASTEVPLKEEIWNKISAFFSSEHQVEAQNCIAYLCHPPETASPEEIKSKFECLRMLAFPAYADNIQYSRGGADQYCILSENSQEILSIVFNTEGYTVEGGGKSVTYTRVTESEQASSASGSKDAVNYELIWSEWVKEAPAKEAANREEAVQRMRDCLKNNKTELRLKILGLTTIPAYIPEQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPHFRGEGPQPTRIIVEYNPFSERTIQNMQRLMSSVDYQGPRVLFAMGDFSIVRVTRPLHQAVQGWLTSLEEEDVNQWRAFEAEANAAAFSGFLDYLGDTQNTRHPDFKEQVSAWLMRLAEDSALRETVFIIAMNATISCEDRVTLAYHQMQEATLVHDAERGAFDSHLAELIMAGREIFRLEQIESLAREKVKRLFFIDEVEVFLGFQNQLRESLSLTTMTRDMRFYNVSGITESDLDEAEIRIKMAENRDFHKWFALWGPWHKVLERIAPEEWREMMAKRDECIETDEYQSRVNAELEDLRIADDSDAERTTEVQMDAERAIGIKIMEEINQTLFTEIMENILLKKEVSSLMSAYWR
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.  Can ubiquitinate both ubiquitin and host TXN (thioredoxin).  Leads to significant decrease of thioredoxin activity and increase of host cell death.
What are the official names of this protein?
E3 ubiquitin-protein ligase SlrP, RING-type E3 ubiquitin transferase SlrP, Secreted effector protein SlrP.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm.
Protein: MURA_HAMD5
Sequence: MKKFRIQGPCSLSGEVMISGSKNAALPILFSTLLSEEPIELKNIPELKDIDTTLNLLKQLGVKAKYQPPDSIMIDAKAVNHFCAPYELVKTMRASIWALGPLVARFGRGQVSLPGGCAIGARPVDLHIFGLKQLGAKIQIEEGYIKASVEGRLKGAHIVMDKVSVGATLTVMSAATLAEGTSIIENVAREPEIVDTANFLNILGANIQGAGTDKIVVEGVKRLRGGAYSIMPDRIETGTFLVAGAVSRGKVVCRHTQPATLEAVLAKLHEAGAQIEVGKDWISLDMKGKRPKAVNVRTTPYPGFPTDMQAQFTLLNIVATGTGVITETIFENRFMHVPELIRMGAQVKIESNTVICHGVERLSGAGVMATDLRASASLVLAGCIAQGITTVERIYHIDRGYECIENKLRKLGAYIERIQGAQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_CHRVO
Sequence: MQLSDFDYHLPEALIAQHPPAERGASRLLHVDGMTLSDLSFADLPSRLQAGDLLVFNDTRVIRARLFGEKASGGKVEALIERVLDDHTALAHVRASKSPKPGSRLIFAGRWEAEMVERHDSMFKLRFLAEENVYDILEASGKLPLPPYIERSAEHDDDERYQTVYAREQGAVAAPTAGLHFTDAMLATLQAQGIATAFVTLHVGAGTFQPVKVDNVAEHKMHSEIYDIPQATVDAIAAARARGGRVVAVGTTSVRALESAARHGELKAGRGETDIFITPGYRFRVVDRLLTNFHLPKSTLLMLVSAFAGYDEIFQAYRHAVEKEYRFFSYGDAMLLEKKV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRA_SHISS
Sequence: MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQHGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSADILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGVAHIPQLKD
What are the official names of this protein?
Protein CbrA.
What is the protein family that this protein belongs to?
Belongs to the CbrA family.