PharMolix/UniProtQA huggingface dataset:
Protein: ACTP2_PHYSE
Sequence: MRHFVVFLYMFLALSIPTAFAKKHIVTKKGNHQDITNDNEGENAEKKSATVAGAVIAGGELALKILTKILYEIGKIDRKIAIGVDNESGLKWTALNTYYKSGASDVTLPYEVENSKALLYTARKSKGPVARGAVGVLAYKMSSGNTLAVMFSVPFDYNLYSNWWNVKIYDGEKKADEKMYNELYNNNNPIKPSTWEKRDLGKDGLKLRGFMTSNGDAKLVIHIEKS
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
DELTA-alicitoxin-Pse1b, DELTA-ALTX-Pse1b, Pst-I.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: ZFX_BOVIN
Sequence: MDEDGLELQPQEPNSFFDTTGADATHMDGDQIVVEVQETVFVSDVVDSDITVHNFVPDDPDSVVIQDVIEDVVIEDVQCPDIMEEADVSETVIIPEQVLDSDVTEEVSLAHCTVPDDVLASDITSASMSMPEHVLTSESIHVSDIGHVEHVVHDSVVEAEIVTDPLTADVVSEEVLVADCASEAVIDANGIPVDQQEDDKGNCEDYLMISLDDAGKIEHDGSSGMTMDAESEIDPCKVDGTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNNSIRVPREKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAAAAAAAAAHEQQMDDNEIKTFMPIAWAAAYGNNSDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTVYPCMICGKKFKSRGFLKRHMKNHPEHLTKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMRHHKEVGLP
What is the function of this protein?
Probable transcriptional activator.
What are the official names of this protein?
Zinc finger X-chromosomal protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FER_PYRAB
Sequence: MAWKVSVDQDTCIGDAICASLCPDVFEMNDEGKAQPKVEIIEDEELYNCAKEAMESCPVSAITIEEA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: AGLC_METVO
Sequence: MNFISIIIPTFNEEKYITKCLENWFNQDYPKENYEILIFDGKSTDKTLDVIKELQKKHNFENIKIYTNEKRKQVYAFNEGIKNANGDFFIIFGAHAYPEQDFLKNNIETYQRIKKEEPKLAGVGGIINKISENMSAEIAKVIYSTPLSGGSSFWYAKEGFFSNTVVYGMYDTKMIKESEILFDTDFITGQDFEFNLHLIKEGFKLYTNPNIVSSYYTRSSVKKFIKQTISYGAAKGLMIRKGYFNILWLFPFGFLFMLLSIIITGLLIFIYIMAILIDTIRLLIKTREPLYIALPILLFLFHCLISYGFFKGLIKGNSTFK
What is the function of this protein?
Involved in the assembly of an N-linked disaccharide that decorates the S-layer glycoprotein and flagellins (PubMed:18978056).  AglC catalyzes the transfer of 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid (Glc-2,3-diNAcA) from uridine 5'-diphospho 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid (UDP-Glc-2,3-diNAcA) to the AglK product Dol-P-GlcNAc to yield Dol-P-GlcNAc-Glc-2,3-diNAcA (PubMed:23624439).  AglC is specific for the monophosphate-linked Dol-P-GlcNAc (PubMed:23624439).
What are the official names of this protein?
Dolichyl N-acetyl-alpha-D-glucosaminyl phosphate 3-beta-D-2,3-diacetamido-2,3-dideoxy-beta-D-glucuronosyltransferase, Glc-2,3-diNAcA glycosyltransferase, UDP-Glc-2,3-diNAcA glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRC_PSEPW
Sequence: MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRNADEAGAYRERILNARPAGSRFEPLMVLYLTDRTSPEDIRAAKASGIVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRLVERFPTLKVVFEHITTADAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPDSLPFGEQTVIPLRAGEKLRWRLLEDNA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RS20_RHIWR
Sequence: MANTPQAKKRIRRNDRRAEINGARVSRIRTFVKKVEAALAAGDKTAATAALAAAQPELFRGVSKGVVHKNTASRKFSRLTKRIAALG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NMO_STAA3
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKITEEQQFKCHIDTIIKKQVPVCCFTFGIPSEQIISRLKAANVKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVITKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELIHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: CSGC_SALTY
Sequence: MHTLLLLAALSNQITFTTTQQGDIYTVIPQVTLNEPCVCQVQILSVRDGVGGQSHTQQKQTLSLPANQPIELSRLSVNISSEDSVKIIVTVSDGQSLHLSQQWPPSAQ
What is the function of this protein?
Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers.  Assembly may also require CsgE.  Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity).
What are the official names of this protein?
Curli assembly protein CsgC.
What is the protein family that this protein belongs to?
Belongs to the CsgC/AgfC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SUMT_METBF
Sequence: MSGNYGKVYLVGSGPGDPELLTLKARRLIDSAEVIVYDQLPGKAILDSMPASAEKINVGKYAGSHTMTQAEINEVLVQKAKEGKMVVRLKGGDPYVFGRGGEEAEVLVAEEIEFEVVPGITSAIAVPAYAGIPVTHRESTSMVTFITGHEDPTKEESGLDWETLAKFGGTIVILMGVKMLGRNAEELMKHGKAPDTPVAVIERGTRADQRVTVGTLANIASLAEERKVKAPAITVVGDVVHLHDILGEQRTGVDF
What is the function of this protein?
Involved in the archaeal biosynthesis of heme.  Catalyzes the methylation of carbons 2 and 7 of uroporphyrinogen-III (UROGEN) to yield precorrin-2.  It does not catalyze the overmethylation of precorrin-2 to trimethylpyrrocorphin.
What are the official names of this protein?
S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase, Mba_SUMT, SUMT, Uroporphyrinogen-III C-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: GTAI_DICDI
Sequence: MTSFLLFNPGSLQQQQQPHSFSKDFINNNNNNNNNCQSSFSTPLGGSNGINNPNATTNNTTTTTTTTTTTTNPLSGSTGINNSNIEVIDIDQCLKHCGCRNPKELIQLIRSDAIENVEISWPDDMGLWYMNTIKSHEVSLQNLVEGVRVAGQLLLLDPTSARFDLSKKQKTIVVRSVNIDRSSSSLSSEDDDCCYETEEDDNGEDGEVVRSPQSKFSLLLDESEKFRKSFSLKKSSRSAFKKNKKDYHHGSSAGGGGSSGGVVVLHYDNNGNQLHYSNSMTDNNSRHHQHGGVGDGYPHSPPAAGGKSLGKRGYQQWSNSNNNNNNNNNNNNNNNGASGFVQSDEDLDASWLEEIKRNRAEVVPDLSSPALFSMDKRSPSPTLGSSCGSSSPGLNNSGNEMNNSQDSPLGVSGGNGNSLNISSGIQCPPGANIDSAEKAILEGQIHLPPLLRPRQYHACKTSKENRPTKRRKNHTSLFCRHCGTTDTPEWRRGPDGRKSLCNACGLHYSKLVKRENMAVPELSRTFELSEILNPSD
What are the official names of this protein?
GATA zinc finger domain-containing protein 9.
Protein: ENGB_XANC8
Sequence: MSLLIEQARYHLSAHNARQLPDDGGYEVAFAGRSNAGKSSALNALTRQNSLARVSKTPGRTQQLVFFQIQPERYLVDLPGYGYAKVPQDLQAHWQAFIDRYFRTREALRGLVVVMDIRHPLKDYDLQMLGYAAERGLPAHGLLTKADKLGRGQQMQTLQKVKKEVSSRFGDSVTVQTYSGESRQGVDELRGIVGGWLGLDVEPPADA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL15_METSB
Sequence: MKLNEIQDNPGSSKSRMRVGRGIGSGKGKTCGRGVKGQKARTGVAIKGFEGGQMPLHRRLPKRGFYNPFGLDYNEINLGRLQEAVDAGRIDVAAVVTNESLIASGLISKPRDGVKILGVGELKAKLSFQVAAASKSAVAAIEAAGGSIELLKRAPEAPTASAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RUVC_PSEFS
Sequence: MTLILGIDPGSRITGFGVVQQTPRGCVYVASGCIRTGAGELAERLQIVYRGVREVIQTYGPVTMGIEKVFMAKNADSALKLGQARGAAIVAGAEEGMEIAEYTATQVKQAVVGTGAANKEQVQMMVMHMLKLTSKPQIDASDALAIAICHAHTRSSLLPHGLGAARSRGGRLRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RS18_XYLFM
Sequence: MSKFFRRRKFCKFTAEGIKEIDYKDLNTLRQYLTENGRIVPSRVTGTKSKYQRQLTTAVKLARFLALIPYTDNHDI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MIX1_XENLA
Sequence: MDGFSQQLEDLYPSCFSPCPSPLGFSEPVIQPFAMNLAPAAQKDFQQHPNRREVTKIPGAGEQSPVQNVRPKDAINPKEADPRSPTADASLVPASQRRKRTFFTQAQLDILEQFFQTNMYPDIHHREELARHIYIPESRIQVWFQNRRAKVRRQGAKATKPILAGHHYSGTSGANRAMFPSAPAPNSSSHQMTTSRAQVQPLKESQMNMFHQNQGFLPYPDSSCNVSRQRFLMSQPTPGAYHLPQASSNVYNQNVKSQNPLWNQQTTNRVYTNMMETVLDLSRRPSQQMPVQPMLMNSFQTNKNIKPEVYTTSPQIPVSTTSSQVSLFANQEPCHMSTTQGGTYGQISPISDSGVSDTSPEPSSDWEENVASVLLNL
What is the function of this protein?
Transcription factor which plays a regulatory role in the development of the embryo.  Involved in the establishment of dorsal/ventral pattern in the early mesoderm.  Activates the head organizer gene cer1 by acting synergistically with otx2 and siamois through the 5'-TAATCT-3' element of the cer1 promoter.  Also binds as a complex with lhx1/lim1 and siamois to the 3x 5'-TAAT-3' element of the cer1 promoter.
What are the official names of this protein?
Homeobox protein Mix.1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DOC11_HUMAN
Sequence: MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV
What is the function of this protein?
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.  Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology.  Facilitates filopodia formation through the activation of CDC42.
What are the official names of this protein?
Dedicator of cytokinesis protein 11, Activated Cdc42-associated guanine nucleotide exchange factor, ACG, Zizimin-2.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
Protein: SPZ5_ORYSJ
Sequence: MAPPPPAAPPCPGLTELALRVARRIQAGGAPDGNLVFSPLSVYAALALVAAGAGGDTLAELLGVLGAGSRDELAGLAGRLAGRALADRSRAGGPRVSFVSGVWYDKTRTLSPSFRDAAVQSFMAETRAADFREKPGEAVNQINAWARKATNKLIDTVIDGGLPADTDVVVANAVYFKGKWKDPFTKALTKTGKFHRLDGAAVDASFMQRGTYYDTGDYIACHDGFKVLRLPYDDERRRSPASPPPPPSTPRFSLCVFLPDALDGLWDLLDEIASTPGFLQAKLPTRHASVGELKLPKFKLTFSGDIAGVLRGLGLDATFSDGEADFSKMVEDDGGRRPLSMRSLVHKAVIEVNEEGTEAAASAINMVCGMSMTPEPRPVPVDFVADHPFAFFVIEETTGAVVFAGHVLDPSSTAGALDDDDDDDEFVVMGCLRYLLDRCMAFVGV
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Putative serpin-Z5, OrysaZ5.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: Y4613_BACCR
Sequence: MKVSYHGHSVVKIEANGKVILIDPFLTGNPKTDLKTEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVNTHPMHIGGSHEFDFGKVKFTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTVYHAGDTALFSDMKLIGELNKVDLAFLPIGDNFTMGPEDAVLAAKWINAKTVVPMHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BC_4613.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: CFA20_BOVIN
Sequence: MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIEGTNVSTTYITCPADPKKTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRVYFSDRLYSEDELPAEFKLYLPVQNKAKQ
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (PubMed:34715025).  Involved in the regulation of the size and morphology of cilia.  Required for axonemal microtubules polyglutamylation (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 20.
What is the protein family that this protein belongs to?
Belongs to the CFAP20 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: RS4E_METMA
Sequence: MTHQKRLSVPKSWKVGRKGNKWISTTRPGPHSQARSLPLGLIIRDVLKLVDNNREGKRILSEGKVLVDGISRKDLRFPVGLFDVITLPLVNEAYRMLQDEKGRLVLYKLNETNVNKLCRINNKTTVKGGKIQLNLNDGTNILGSNDYGTKDSLILSIPDKHVVKHLKFEVGNLAMVIGGQHSGETGKIMEIREVKSSRHNTVMISGETDFETIEDYVIVIGEDKPEIRLGGEISE
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: RUVB_HAMD5
Sequence: MIEIDRLVSTDVLNENEALVDRAIRPKRLDEYVGQSHVRDQMQIFIQAAKQRGDALDHLLIFGPPGLGKTTLANIVAHEMGVNLRTTSGPVLEKAGDLAALLTHLEPRDALFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPGARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYSVPDLEHIVSRSARCLQLPLTKNGAHQLALRSRGTPRIINRLLRRVRDFAEVKGEGKINTEIAIKALEMLNVDKEGLDYMDSKLLLAIIEKFQGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATQHAYQHFICGG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: FABH_HELPY
Sequence: MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFANDEEKSSDLGVIAAKQAIERAHLTPKDIDLVVVATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMYENVLIVGAEKTSSVLDFKDRGTCILFGDGAGACVIGRTKRLKESILDVQISANGNFSNYLYTPRTLKPTPFNAKEEASEPFLCMKGNEVFKLAVKTLLKDVEMILEKNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMGEAYEEGRLKKGDLMLLDAFGGGLTWGSALVYFGGS
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECDC_LYMDI
Sequence: IAIFNAYTPLPFAD
What is the function of this protein?
Stimulates synthesis of ecdysteroid in the testes of larvae and pupae.
What are the official names of this protein?
Testis ecdysiotropin peptide C, TE.
Protein: RECA_STRP2
Sequence: MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYVC_MOUSE
Sequence: MSILYVSPHPDAFPSLRALIAARYGEAGDGPGWGGPHPRICLQPPPSSRTPFPPPRLPALEQGPGGLWVWGAPAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRGPGQDPQAALGALGKALNPLEDWLRLHTYLAGDAPTLADLAAVTALLLPFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVALYSGARSVTQQPGSEVIAPQKTPAQLKKEAKKREKLEKFQQKQKTQQQPPHGEKKPKPEKKEKRDPGVITYDLPTPPGEKKDVSGAMPDSYSPQYVEAAWYPWWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLEEVWKWKAEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSATVTEAFVRLHEEGVIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLPVPGYKEKVEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDPRYQHLKGKCVVHPFLSRSLPIVFDDFVDMEFGTGAVKITPAHDQNDYEVGQRHRLEAISIMDSKGALINVPPPFLGLPRFEARKAVLAALKERGLFRGVKDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPEAHQRTWHSWMDNIRDWCISRQLWWGHRIPAYFITVHDPAVPPGEDPDGRYWVSGRTEAEAREKAAREFGVSPDKISLQQDEDVLDTWFSSGLFPFSIFGWPNQSEDLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGKLPFREVYLHAIVRDAHGRKMSKSLGNVIDPLDVIHGVSLQGLYDQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCAYTSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSATSKPEGHESLVDRWIRSRLTEAVRLSNEGFQAYDFPAITTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQTLYTCLDVGLRLLSPFMPFVTEELFQRLPRRTPKAPASLCVTPYPEPSECSWKDPEAEAALELALSITRAVRSLRADYNLTRTRPDCFLEVADEATGALASAVSGYVQALASAGVVAVLALGAPAPQGCAVAVASDRCSIHLQLQGLVDPARELGKLQAKRSEAQRQAQRLQERRAASSYSAKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML
What are the official names of this protein?
Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: NAHE2_PSEPU
Sequence: MSNKIMKTSRLTAEDINGAWTIMPTPSTPDASDWRSTATVDLEETARIVEELIAAGVNGILSMGTFGECATLTWDEKRDYVSTIVETIRGRVPYFCGTTALNTREVIRQTRELIDIGANGTMLGVPMWVKMDLPTAVQFYRDVADAVPEAAIAIYANPEAFKFDFPRPFWAEMSKIPQVVTAKYLGIGMLDLDLRLAPNIRFLPHEDDYYAAARINPERITAFWSSGAMCGPATAIMLRDEVVRAKSTGDWAKAKAISDDMRAADSTLFPRGDFSEFSKYNIGLEKARMDAAGWLKAGPCRPPYNLVPEDYLAGAQKSGKAWAALHAKYSNELK
What is the function of this protein?
Involved in the naphthalene upper catabolic pathway.  Catalyzes the transformation of trans-O-hydroxybenzylidenepyruvate (THBPA) to salicylaldehyde and pyruvate.  The reaction is reversible (By similarity).
What are the official names of this protein?
Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase, THBPA hydratase-aldolase, 2'-hydroxybenzalpyruvate aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.