PharMolix/UniProtQA huggingface dataset:
Protein: L_MEASE
Sequence: MDSLSVNQILYPEVHLDSPIVTNKIVAILEYARVPHAYSLEDPTLCQNIKHRLKNGFSNQMIINNVEVGNVIKSKLRSYPAHSHIPYPNCNQDLFNIEDKESTRKIRELLKKGNSLYSKVSDKVFQCLRDTNSRLGLGSELREDIKEKVINLGVYMHSSQWFEPFLFWFTVKTEMRSVIKSQTHTCHRRRHTPVFFTGSSVELLISRDLVAIISKESQHVYYLTFELVLMYCDVIEGRLMTETAMTIDARYTELLGRVRYMWKLIDGFFPALGNPTYQIVAMLEPLSLAYLQLRDITVELRGAFLNHCFTEIHDVLDQNGFSDEGTYHELIEALDYIFITDDIHLTGEIFSFFRSFGHPRLEAVTAAENVRKYMNQPKVIVYETLMKGHAIFCGIIINGYRDRHGGSWPPLTLPLHAADTIRNAQASGEGLTHEQCVDNWKSFAGVKFGCFMPLSLDSDLTMYLKDKALAALQREWDSVYPKEFLRYDPPKGTGSRRLVDVFLNDSSFDPYDVIMYVVSGAYLHDPEFNLSYSLQEKEIKETGRLFAKMTYKMRACQVIAENLISNGIGKYFKDNGMAKDEQDLTKALHTLAVSGVPKDLKESHRGGPVLKTYSRSPVHTSTRNVRAAKGFIGFPQVIRQDQDTDHPENMEAYETVSAFITTDLKKYCLNWRYETISLFAQRLNEIYGLPSFFQWLHKRLETSVLYVSDPHCPPDLDAHIPLYKVPNDQIFIKYPMGGIEGYCQKLWTISTIPYLYLAAYESGVRIASLVQGDNQTIAVTKRVPSTWPYNLKKREAARVTRDYFVILRQRLHDIGHHLKANETIVSSHFFVYSKGIYYDGLLVSQSLKSIARCVFWSETIVDETRAACSNIATTMAKSIERGYDRYLAYSLNFLKVIQQILISLGFTINSTMTRDVVIPLLTNNDLLIRMALLPAPIGGMNYLNMSRLFVRNIGDPVTSSIADLKRMILASLMPEETLHQVMTQQPGDSSFLDWASDPYSANLVCVQSITRLLKNITARFVLIHSPNPMLKGLFHDDSKEEDEGLAAFLMDRHIIVPRAAHEILDHSVTGARESIAGMLDTTKGLIRASMRKGGLTSRVITRLSNYDYEQFRAGMVLLTGRKRNVLIDKESCSVQLARALRSHMWARLARGRPIYGLEVPDVLESMRGHLIRRHETCVICECGSVNYGWFFVPSGCQLDDIDKETSSLRVPYIGSTTDERTDMKLAFVRAPSRSLRSAVRIATVYSWAYGDDDSSWNEAWLLARQRANVSLEELRVITPISTSTNLAHRLRDRSTQVKYSGTSLVRVARYTTISNDNLSFVISDKKVDTNFIYQQGMLLGLGVLETLFRLEKDTGSSNTVLHLHVETDCCVIPMIDHPRIPSSRKLELRAELCTNPLIYDNAPLIDRDATRLYTQSHRRHLVEFVTWSTPQLYHILAKSTALSMIDLVTKFEKDHMNEISALIGDDDINSFITEFLLIEPRLFTIYLGQCAAINWAFDVHYHRPSGKYQMGELLSSFLSRMSKGVFKVLVNALSHPKIYKKFWHCGIIEPIHGPSLDAQNLHTTVCNMVYTCYMTYLDLLLNEELEEFTFLLCESDEDVVPDRFDNIQAKHLCVLADLYCQPGTCPPIQGLRPVEKCAVLTDHIKAEAMLSPAGSSWNINPIIVDHYSCSLTYLRRGSIKQIRLRVDPGFIFDALAEVNVSQPKIGSNNISNMSIKAFRPPHDDVAKLLKDINTSKHNLPISGGNLANYEIHAFRRIGLNSSACYKAVEISTLIRRCLEPGEDGLFLGEGSGSMLITYKEILKLSKCFYNSGVSANSRSGQRELAPYPSEVGLVEHRMGVGNIVKVLFNGRPEVTWVGSVDCFNFIVSNIPTSSVGFIHSDIETLPDKDTIEKLEELAAILSMALLLGKIGSILVIKLMPFSGDFVQGFISYVGSHYREVNLVYPRYSNFISTESYLVMTDLKANRLMNPEKIKQQIIESSVRTSPGLIGHILSIKQLSCIQAIVGDAVSRGDINPTLKKLTPIEQVLINCGLAINGPKLCKELIHHDVASGQDGLLNSILILYRELARFKDNQRSQQGMFHAYPVLVSSRQRELISRITRKFWGHILLYSGNRKLINKFIQNLKSGYLILDLHQNIFVKNLSKSEKQIIMTGGLKREWVFKVTVKETKEWYKLVGYSALIKD
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PSA2_CARAU
Sequence: MADRGYSFSLTTFSPSGKLVQIEYALAAVAAGAPSVGIKASNGVVLATEKKQKSILYDEQSVHKIEPITKHIGMVYSGMGPDYRVLVRRARKLAQQYFLVYQEPIPTGQLVQRVASVMQEYTQSGGVRPFGVSLLIAGWDEDRPYLFQSDPSGAYFAWKATAMGKSYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMTEENIEVGICNEAGFRRLSPAEVKDYLAAIA
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation (By similarity).
What are the official names of this protein?
Proteasome subunit alpha type-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MP702_ORYSJ
Sequence: MADGGGGEEGSASALRGSARRRGAVQPAGLDADELLTLMHGSDPVKVELNRLENEVRDKDRELGDAHAEIKALRLSERAREKAVEELTAEYEKLDEKLKLTESLLESKNLELKKTNDEKKAAMAAQFAAEATLRRVHAAQKDDDMPPIEAILAPLEAELKLARQEIAKLQDDNRALDRLTKQKEAALLEAERTVEIALAKAAMVDDMQNKNQELMKQIEICQEENKILDRLHRQKVAEVEKLSQTVRELEEAVLAGGAAANAVRDYQRKVQEMNEERKILDRELARAKVTANRVAVVVANEWKDANDKVMPVKQWLEERRFLQGEMQQLRDKLAIAERTARSEAQLKEKYQLRLKVLEDGLRGPPSGSSRPTEGKSIGNGPSRRLSLGGADNMSKISPNGMLARRSPSFNSRSSLSTSSSLVIKHAKGTSRSFDGGTRSLDRGKVLGNGPHLLNRSTDAVRDCETTDDWKAANTEEKGSEATNSSSTDTVSGVLYDMLQKEVISLRKACHEKDQSLKDKDDAIEMLAKKVDTLTKAMEVEAKKMRREVAAMEKEVAAMRLDKDQENKAKRPGNFKGPGTTSQAPHGRNAPRGGLTRNLQ
What is the function of this protein?
Plant-specific protein that interact with microtubules.
What are the official names of this protein?
Microtubule-associated protein 70-2, AtMAP70-2, 70 kDa microtubule-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAP70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated to microtubules.
Protein: E1BS_ADECC
Sequence: MDPLKICENYLTFRSIIKGSTFSPGVFRRWRFHALADVVGNIVEREEGRFWEIVPETHTLWALFRGGFTVAPFTEILTSLQLENRGRQLAFLAFLSFLLRNWPSDSVVSEDARLDLVCAPAWSRIQIWSQAARLINDLPESVFEGQGSVVEEECGEEHLARDSDDPLFD
What are the official names of this protein?
E1B protein, small T-antigen, E1B 19 kDa protein, E1B-19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 19 kDa protein family.
Protein: REX_BACCR
Sequence: MDQQKIPQATAKRLPLYYRFIQNLSLSGKQRVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVNYLLSFFRETLDQDDITRVALIGVGNLGTAFLHYNFTKNNNTKIEMAFDVSEEKVGTEIGGIPVYHLDELEERLSNDIQVAILTVPATVAQAVADRLAETSVHGILNFTPARLNVSENIRIHHIDLAVELQTLVYFLKNYPQ
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_XANAC
Sequence: MSTVEPNVYDPQQVETSAQQFWDATRAFQVDENSEKPKFYCLSMLPYPSGALHMGHVRNYTISDVVSRYKRMTGHNVLQPMGWDAFGLPAENAAIKNKTAPAKWTYANIEHMRAQLKSLGYAIDWSREFATCTPDYYVHEQRMFTRLMRKGLAYRRNAVVNWDPIDQTVLANEQVIDGRGWRSGAVVEKREIPQWFLRITDYAQELLDGLDQLDGWPDSVKTMQRNWIGRSEGLEIQFDVRDPDGATLDPLRVFTTRPDTLMGVTFVSIAAEHPLALHAAKSNPELAALLETLKHGGVSEAELETQEKRGMATGLTAVHPISGEQVPVWVANFVLMGYGTGAVMAVPGHDQRDFEFANKYGLPIVQVVKLREPRNEEEQTWDATHWRDWYTDKSRELELINSAEFDGLDFGGAFEALAERFERKGQGQRRVNYRLRDWGVSRQRYWGCPIPVIYCAKCGAVPVPEDQLPVVLPENVEFSGTGSPIKTDPTWRQTTCPDCGGPAERETDTFDTFMESSWYVARYTSPKARDMVDRRANYWMPADLYVGGIEHAILHLMYFRFYHKLMRDARLVDSDEPVTNLLTQGMVIADTFYRDADNGGKDWINPADVEIQRDERGRVTGAVLIADGQPVQIGGTEKMSKSKNNGVDPQSMVAKYGADTVRLFSMFAAPPEQSLEWNEAGVDGMARFMRRLWAQVHKHVGEGTAVALDVAALSAEQKAIRRKTHETIGKVGDDYGRRHSFNTAIAAVMELSNALAKFDDASEQGRAVRQEALEAMVLLLNPITPHASHALWQVLGRGETLLENVAFPQADASALVRDALTLAVQINGKLRGTIDVAADATREQIEALAQAEPNAAKFLEGLSVRKIIIVPGKIVNIVAG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_VIBPA
Sequence: MRTSHMLEQLMEALRCLPGVGPKSAQRMAFHLLQRDRKGGLQLADALSQSMTEIGHCAECRTFTEEEVCHICTNPKRQENGQICVVESPADIAAVEATGQYSGRYFVLMGHLSPLDGIGPSDIGLDVLDYRLRRGDISEVILATNPTVEGEATAHYIAELCREHQVEASRIAHGVPVGGELELVDGTTLSHSLLGRHKI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: IF3_SYNS9
Sequence: MAPRPRFDRRAPVRELPNINDRISYPQLRVVDSDGSQLGVISREEALEVSKERELDLVLVSEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDSHDYDVRIGQAQRFLKAGDKVKCTVIFRGREIQHTALAEVLLRRMAKDLEEKAEIQQSPKREGRNMIMFLTPRKTPLLKKDDKDSSVHQAIRTIPAPPRSTAAKVAAPQA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APBA1_MOUSE
Sequence: MNHLEGSAEVEVADEAPGGEVNESVEADLEHPEVVEGQQPSPSPPPPAGHEPEDHRGHPAPPPPPPPQEEEEEERGECLARSASTESGFHNHTDTAEGDVLAAARDGYEAERAQDADDESAYAVQYRPEAEEYTEQAEAEHVEAAQRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRAEDEPYAEPYADYGGLQEHVYEEIGDAPELEARDGLRLYERERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERAPTPGGGHPDSPGLPAPAGQQQRVVGTPGGSEVGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPVDGDSPSPGSSSPLGAESSSIPLHPGDPTEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKTAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
What is the function of this protein?
Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery.  May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta (By similarity).  Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (PubMed:10846156).
What are the official names of this protein?
Amyloid-beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1, Mint-1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Golgi apparatus.
Protein: PSBT_CABCA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKAK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUDL_ECOLI
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RBS2_ACEAT
Sequence: VVLSKECAKPLATPKVTLNKRGFATTIATKNREMMVWQPFNNKMFETFSFLPPLTDEQISKQVDYILTNSWTPCLEFAASDQAYAGNENCIRMGPVASTYQDNRYWTMWKLPMFGCTDGSQVLSEIQACTKAFPDAYIRLVCFDANRQVQISGFLVHRPPSATDYRLPADRQV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 2, RuBisCO small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEXA_CARHZ
Sequence: MKNSLLSHQEKKIISFIKQYLNENGYPPTIREICQGVGLSSPSTVHHHLKNLESKGYLQRNPTKPRALELVAEKAPEELLSIPLLGNVAAGYPTLAIENAEEEMQIPKSLFPEKELFALRIKGDSMIEEGILPGDVIIVKKQEVAENGDIVVAYLEGEVTVKKFWKDSVNGVIKLIPANSKYEPIIINRETKILGKVIGLLRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MUTS_STRGC
Sequence: MATEKISPGMQQYLDIKKDYQDAFLLFRMGDFYELFYEDAVNAAQILEIALTSRNKNSENPIPMAGVPYHSAQQYIDVLIESGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPVGENNFLVALDRQEQAYGLAYMDLATGEFQVTSLADFDQACGEIRNLRAREVVVGYCLSEDEQQILSKQMNLLLSEVEEAMEDVQLLGDELSSLEKQTAGKLLAYVFQTQMRELSHLKKVHHYEIKDFLQMDYATKTSLDLTENARTGKKHGSLFWLMDETKTAMGGRLLRSWIQHPLIDKGRIIKRQDVVQVFLDYFFERSDLADSLKGVYDIERLVSRVSFGKTNPKDLLQLASTLSHVPQIRSILETIESPALESLVARLDAIPELENLISSAIDPDAPQVITEGNIIRTGFDETLDQYRLVMREGTSWIADIEAKEREASGITNLKIDYNKKDGYYFHVTNSQLGNVPSHFFRKATLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQTLATVDVLQSFAVVAESQHLVRPSFTSSRSLQIKKGRHAVVEKVMGAQSYIPNSIELDQETDIQLITGPNMSGKSTYMRQLAMIVIMAQMGSYVPAEVASLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANRAIRQASERSLILFDELGRGTATYDGMALAQAIIEYIHDRTKAKTLFATHYHELTDLSSSLTRLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPTDLLRRADAILTDLENQEKREASLPASRTDSQKVSEQMSLFVEETENPVLTELRDLDIYNMTPLEVMAAVAELKKKL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FOSB_BACC7
Sequence: MLKGINHLCFSVSNLEDSITFYEKVLEGELLVRGRKLAYFNICGVWIALNEEIHIPRNEIHQSYTHIAFSVEQKDFERLLQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQDRLNYYREGKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_ECOSE
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RL20_AGRVS
Sequence: MSRVKRGVAAHAKHKKVLKAAKGFYGRRKNTIRAAKAAVDRSKQFAYRDRKVNKRNFRALWIQRINAAVRESGLTYGRFIDGLNKAGIEVDRKVLSDMAIHEPAAFGALVEASKKALSYLKDTGTKNEFETAVK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DIR7_ARATH
Sequence: MAKLILIIVTQILLIAAVVSARKGENFAKTIDKKHFGLRKEKLTHFRVYWHDILSGSNPSSVVINPPISNSSFFGSVTVIDNRLTTEVAVNSTLVGQAQGIYAATGQRDASALMVMNFAFKTGKYNGSSIAILGRNAVLTKVREMPVIGGSGLFRFARGYVEARTMWFDQKSGDATVEYSCYVLHY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 7, AtDIR7.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: MURA_PSEA6
Sequence: MDKLLIKASKPLQGSVRISGAKNAALPILMSSILADTTCYFDNVPELRDINTSLALLAELGADAKRVSGHAVEIDPSSINNCNASYDLVKTMRASILVLGPLLAKYGEANVSLPGGCAIGARPVNLHLQGLEKMGAKIDVEAGYIRAKVDGRLKGANIFMDMVSVGATENLMMAACLADGETVLENAAREPEIVDLANCLNAMGAKVTHAGSDKIRIQGVERLQGCRYAVLPDRIETGTFLIAAAVTGGKIRCENAAPETLDAVLDKLVMAGAVITTGDDWIELDMQGHPLTSVNIKTAPHPGFPTDMQAQFVALNCVAQGTGVVTENIFENRFMHVPELQRMGAKIDLETNSAVCHGVSSLKGAQVMATDLRASASLVIAGLVAEGETVVDRIYHLDRGYEHIETKLNGLGANIQRIK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO4A_HUMAN
Sequence: MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQPDCREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDEDDIPVRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV
What is the function of this protein?
Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process.  It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
What are the official names of this protein?
Complement C4-A, Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2.
What are the subcellular locations of this protein?
Secreted. Synapse. Cell projection, axon. Cell projection, dendrite.
Protein: RHEB_RAT
Sequence: MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM
What is the function of this protein?
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis.  Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling.  Has low intrinsic GTPase activity.
What are the official names of this protein?
GTP-binding protein Rheb, Ras homolog enriched in brain.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rheb family.
What are the subcellular locations of this protein?
Endomembrane system; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side.
Protein: GLRX5_MOUSE
Sequence: MSASLSRAAAALLRWGRSAGGGGLPGAGVRAASSGGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALVDEKDQDSK
What is the function of this protein?
Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed:19442627).  Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (By similarity).  Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (By similarity).
What are the official names of this protein?
Glutaredoxin-related protein 5, mitochondrial, Monothiol glutaredoxin-5.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CAD1_DICDI
Sequence: MSVDANKVKFFFGKNCTGESFEYNKGETVRFNNGDKWNDKFMSCLVGSNVRCNIWEHNEIDTPTPGKFQELAQGSTNNDLTSINGLSKFQVLPGAFQWAVDVKIVNKVNSTAGSYEMTITPYQVDKVACKDGDDFVQLPIPKLTPPDSEIVSHLTVRQTHTPYDYVVNGSVYFKYSPTTGQVTVIKKDETFPKNMTVTQDDNTSFIFNLNSEK
What is the function of this protein?
Mediates calcium-dependent cell-cell adhesion during the early stage of development.
What are the official names of this protein?
Calcium-dependent cell adhesion molecule 1, CAD-1, DdCAD-1, GP24.
What is the protein family that this protein belongs to?
Belongs to the Dictyostelium CAD family.
What are the subcellular locations of this protein?
Cell membrane. Note=Associated with the ecto-surface of the plasma membrane. May be transported to the plasma membrane via contractile vacuoles and its cell surface association may be mediated by an integral membrane protein.
Protein: LCA5L_PAPAN
Sequence: MSLADLTKTNIDEQFSSVALENNRRSAECKRSPGTGDFSRNSNASAKSVDYSRSQCSCGSLSSQYDYSEDFLCDCSEKAINRNYLKQPVVKEKEKKKYNVSKISQSKGQKEISVGKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTVSRKLRETDSQLLKTKDTLQALQKLSEDKNLAEREELTHKLSIITTKMEANDKKIQSLEKQLRLNSRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKSLPFTSMRHQGTQKSDVAPLTTKGKKATGNMDRKEKSTEINREIPHCVNKLPKQEDSKTKYEDLSREEKHLEVQVLLENTGRQKDKKEDQEKKTIFVKEEQELPPKIIEVIHPERESTQEDVLVREKFKRSMQRNGMDDTPDKCTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNTKYSHSTSKHLSNREEMELEHSDSGYEPSFGKSSRIKAKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASASNAFGDSKVTVVNSIKPSSPTEGKRKIII
What are the official names of this protein?
Lebercilin-like protein, Leber congenital amaurosis 5-like protein.
What is the protein family that this protein belongs to?
Belongs to the LCA5 family.
Protein: FRA16_FRAAN
Sequence: MGVFTYETEFTSVIPPPRLFKAFILDADNLIPKIAPQAVKCAEIVEGDGGVGTIKKITFGEGSQFGSVTHKIDGIDKENFVYSYSLVEGDALSDKIEKISYETKLVASSDGGSVIKSTSNYHTKGDVEIKEEHVKAGKEKASHLFKLVEDYLLANPNEYC
What is the function of this protein?
Possesses ribonuclease activity in vitro.
What are the official names of this protein?
Major strawberry allergen Fra a 1.06, Class 10 plant pathogenesis-related protein Fra a 1.06, PR10-related protein Fra a 1.06.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.