PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_BURP1
Sequence: MRIALGIQYDGAAFCGWQSQPHGKTVQDALERSLAEFAQTSLHTTVAGRTDTGVHGLGQVVHFDTDLDRADFSWVRGTNAFLPPTVAVQWAKPMPDTFHARFAAFERTYYYALYVHPVRSPMLAGRAGWVHTPLDVDAMREAAAHLVGEHDFSAFRSSECQAKSPVKHLYQIGIRPDGDFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPSSWLAEVLESRDRDCAAPTFMPEGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDGRT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: AZOR2_BACCZ
Sequence: MSKVLFVKANDRPAEQAVSSKMYETFVNTYKEANPNTEITELDLFALDLPYYGNIAISGGYKRSQGMELTAEEEKAVATVDQYLNQFLEADKVVFAFPLWNFTVPAPLITYISYLSQAGKTFKYTANGPEGLAGGKKVVVLGARGSDYSSEQMAPMEMAVNYVTTVLGFWGITNPETVVIEGHNQYPDRSQQIVEEGLENVKKVAAKF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PSBT_ILLPA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPNKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PFDB_ARCFU
Sequence: MGELPPQVQNLVAQLQQLQQQLQAVITQRAQVEALLRDTEQALEELQKVDDETPVYKAVGNILVKEKKEDVIKELTEKKETYEIRIKTLQRQEEKLRERFAETQQKLQNLLSPQAG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_PEDPA
Sequence: MSLITDIYAREVLDSRGNPTVEVEVYTEDGGFGRGIVPSGASTGEHEAVELRDGDKNRFSGKGVEKAVANVNGPISKEIVGFEVTDQIAIDKAMIKLDGTPNKGKLGANAILGVSLAVARAAADELQVPLYNYIGGSNAHVLPTPMMNVINGGAHSENKVDFQEFMIMPVGAPSVKEAIRMGSETFHALKSLLSADGKATSVGDEGGFAPDFANNEEPLQYLIKAIEKAGYKPGKDVAIAVDVAASELWNDEDKKYKLRWSTGEEFTTEEFVKYLEGLVNKYPIISIEDPIDENNWDDWASITKELGKKVQLVGDDFFVTNTEYLAKGIKMGAANAILIKVNQIGTLTETMESIEMAKEAGYTAIVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEDQLEGVAEYKGINSFYNLSADAREEISNK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYL_DEIRA
Sequence: MTQEATKPNIQEPRAERYNPHAIEQKWQGQWQESGLYKFDENAPGEKFYALTMFPYPSGNLHIGHWYANVAPDARARWLRMRGYNVLFPMAFDAFGLPAENAAIKNNTNPATWTYANIERMTGQFSRMGTMIDWSRKFATCDPEYYRWNQWFFIEFWKRGLAYKKGGLVNWCPKDQTVLANEQVVNGHCERCGTAVERRNLSQWYLKITDYAEELLDFSATDMPEKVRAMQTNWIGKSVGAEVTFDTPAGPETVFTTRPDTLMGATFMVLAPEHAKVKELTTDEQRAEVEAYVAAAGRKTDVERQQEGEKTGVFTGSYATHPISGHQLPIWVADYVLVTYGTGSIMAVPAHDERDFAFAKKFDLPIREVIRAEGSEGMGDQPSEPYSGEGQIVNSGEFDGMPGGKASIAAIIARLEERGVAKAKTTYRLRDWLFARQRYWGTPIPFVHCEKCGMQPVPEDQLPVKLPENVAFTPTGQSPLKLDEEWKTTTCPCCGGPAERETDTMDTFVDSSWYMYRYLSPNYDGGPFDPSKAGLLPVDLYTGGIEHAILHLLYSRFWTKVMRDMGLTTQSEPFARLRNQGMVLGEDGEKMSKSRGNVVDPDDLVREYGADTVRAFLMFIAPWELGGPWDPQGINGPSKWLSRVWNVFFEEKVSGPEEKMQGADVRFAVHSALKKVNDDFERMSFNTIISTLMELTNALVKAKRSPVFGTPVWEEALDIFNRMLAPVVPHIAEEIWHERGQKGSVHTAQWPQVDEAAAVRDTVTIGVQVSGKVRGEVSISKTASQEEALSAARAIAEVQKHLEGKTVVKEIYVPGRIINIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_ECO8A
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PROM4
Sequence: MLSPKRTKFRKQQRGRMRGVATRGNKIAFGQFALQAQECGWITSRQIEASRRAMTRYVKRGGQIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVIKPGRILFEMGGEEITESIAREAMRLAQYKLPIKTKFIALAEGETPTQVGKASSASLANLDEDANSQTDDETSSSGSVATVES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MSRB_STAAE
Sequence: MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: SSRP_THESQ
Sequence: MVKVVATNKKAYTDYEILETYEAGIVLTGTEVKSLRNGSVNFKDSFCRFKNGELYLLNLHIPPYSHGGVYNHDPERPRKLLLHKRELKRLMGKVQEEGVTIVPLKIYFNDRGIAKVEIAVARGKKKYDKREAIKKREMERKIREYMKYSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RNT_PSEE4
Sequence: MSEDLYEDDQDSQVSSGSRHPMAERFRGYLPVVVDVETGGFNSATDALLEIAAVTIGMDEKGFLFPEHTYFYRVEPFEGANIEAAALEFTGIKLDHPLRMAVSEESALTDIFRGVRKALKANGCKRAILVGHNSSFDLGFLNAAVARNDIKRNPFHPFSSFDTATLAGLAYGQTVLARACQSADIDFDGREAHSARYDTEKTAELFCGIVNRWKEMGGWRDFND
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: MRAY_CHLAB
Sequence: MNSGFYLHESLVFFLLTVFALAFILGIFLGKPVIRWLKKRNHYDQVQKEYCEKLEVLHQDKKYTPTAGGILFFIVLLLTIFFWLPLGKLSTWLFAFLIISWSSLGWYDDIVKKRKKKGHGISAKQKFVLQLLISAVITTAVMYIYKGTSLFYTLRVPFFGSVSLGHSVLGQVFYFILAVLAIVGTGNAVNLTDGLDGLAAGTTCMCAFGLLVVAVTSTTIPLATDIPVLLTALLGVSLAFLKYNCSPAQVFMGDTGSLLIGGVLGSCAVMLRAELLLILLGGVFVAEAGSVILQIASCRFRKKRIFLCSPLHHHYEYKGVSETQVVKRFWTAGFFCMVFGIIAALWR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MMPL9_MYCTO
Sequence: MVPGEVHMSDTPSGPHPIIPRTIRLAAIPILLCWLGFTVFVSVAVPPLEAIGETRAVAVAPDDAQSMRAMRRAGKVFNEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQDFWRDPLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEAVRKIVANSTPPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYRSIATTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAGTDYAIFLVGRYQEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCLSFARLTLFHTMGPPLAIGMLVSVAAALTLAPAIIAIAGRFGLLDPKRRLKTRGWRRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAGTPVNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLVIDKIAKEVLHVSGVERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADMLTMSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADIDDFVRPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDMNKMEALTPQFLALLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHATAMGQAFDTAKSGDSFYLPPEAFDNAEFQQGMKLFLSPNGKAVRFVISHESDPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKYDILIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQHFVGLQVHWTIVAMSVIVLLAVGSDYNLLLVSRFKEEVGAGLKTGIIRAMAGTGAVVTSAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPNMIHSRPTVPEAHTRQGARRIQPHLHRG
What are the official names of this protein?
Probable transport protein MmpL9.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXD_THEVB
Sequence: MRLADVAERFGATLDCPEHGDRPVLGVAPLETATATDISFLANPKYTALLQTTQAAAVFVRPDFQGEAACPLLRVPHPYLAFAKCIEWFYPQPKPVAKIHPTAILGADVVLGAEVTIGAYTVIGDRVRIGDRTVIDSHCTLYDDVVIGSDCRIYSHCALRERVQLGDRVILQNSVVLGSDGFGYVPLPDGRHYKIPQVGTVVIGNDVEIGAGTTIDRATLGETTVANGTKIDNLTMVAHNCTIGENAILCAQVGLAGSTHIGNHVVLAGQVGAAGHLTIGDRTVVSAKSGISSSVPPDSRMGGIPAMDQTLYLKVSAAVKQLPDLLKRVRKLEAKVGE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: FABPH_MYOLU
Sequence: MADAFAGTWKLVDSKNFDDYMKSIGVGFATRQVASMTKPTTIIEINGDTIILKTQSTFKNTEISFKLGVELDKTTADDRKVKSTVTLDGGKLVHVQKWDGQETKLVRELVDGKLILTLTHNNVVCTRTYEKEA
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.  FABPs are important elements related to the hibernating state in mammals.
What are the official names of this protein?
Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYX_CROAD
Sequence: MKILYLLFAFLFLAFLSEPGNAYKRCHKKGGHCFPKTVICLPPSSDFGKMDCRWRWKCCKKGSVNNAISI
What is the function of this protein?
Cationic peptide that possesses multiple functions.  It acts as a cell-penetrating peptide (CPP), and as a potent voltage-gated potassium channel (Kv) inhibitor.  It exhibits antimicrobial activities, hind limb paralysis, and severe muscle necrosis by a non-enzymatic mechanism.
What are the official names of this protein?
Myotoxin, CAM-toxin.
What is the protein family that this protein belongs to?
Belongs to the crotamine-myotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSGA_ECOSE
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAAMFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSIEWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1038_NEIMB
Sequence: MSIKQWPEGERPREKLLERGAAALSDAELLAILLRVGTRGMSAVDLARYLLQEFGSLGRLMSAEVGKLSAYKGMGTASFTQFAVVREIGRRILAEELQESIVLSDPDTVADYLRFHLGQEKVEVSVALLLNRQNQLIAVRELSRGTVAENTIYIREIVKLALDEYADSLIIAHNHPGGSPEPSQEDIMFTRRLAQAMSLVDVSLLDHFIVTSQSVCSFRQLGLMP
What are the official names of this protein?
UPF0758 protein NMB1038.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MRS22_ARATH
Sequence: MAQNGYLVPADPSAVVTVKKKTPQASWALIDATGQSEPLDVDKYEIMHRVQIHARDLRILDPNLSYPSTILGRERAIVLNLEHIKAIITSEEVLLRDPSDENVIPVVEELRRRLPVGNASHNGGQGDGKEIAGAQNDGDTGDEDESPFEFRALEVALEAICSFLAARTAELETAAYPALDELTSKISSRNLDRVRKLKSAMTRLTARVQKVRDELEQLLDDDDDMADLYLSRKLSSASSPISSIGEPNWYTTSPTIGSKISRASRASLATVHGDENDVEELEMLLEAYFMQIDSTLNRLTTLREYIDDTEDYINIQLDNHRNQLIQLELVLSSGTVCLSMYSLVAGIFGMNIPYTWNDGHGYMFKYVVGLTGTLCVVVFVIIMSYARYKGLVGS
What is the function of this protein?
Low-affinity magnesium transporter that mediates the influx of magnesium.  Plays a crucial role in male gametophyte development and male fertility.
What are the official names of this protein?
Magnesium transporter MRS2-2, Magnesium Transporter 9, AtMGT9.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCRG_METJA
Sequence: MAYKPQFYPGQTKIAQNRRDHMNPDVQLEKLRDIPDDDVVKIMGHRQPGEDYKTVHPPLEEMDLPEDYVRDLVEPLNGAKEGHRIRYIQFTDSMYFAPAQPYDRARTYMWRFRGVDTGTLSGRQVIEMRESDLEALSKNFLIDTAFFDPARIGIRGATVHGHSLRLDENGLMFDALQRYVYDEKTGHVLYVKDQVGRPLDEPVDVGEPLPEEKLKEITTIYRIDGVPMREDEELLTVVKRIHRARTLGGFLPVEDVFEKL
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase I subunit gamma, MCR I gamma, Coenzyme-B sulfoethylthiotransferase gamma.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGX42_CENNO
Sequence: DRDSCVDKSKCGKYGYYQECQDCCKNAGHNGGTCVYYKCKCNP
What is the function of this protein?
Reversibly blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 4.2, CnErgTx5, CnErg5, ErgTx5, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLX_ECOLI
Sequence: MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADKARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDKLHALRYADSVSMTLSWQR
What is the function of this protein?
Catalyzes the epimerization of carbon 2' of the side chain of 7,8-dihydroneopterin triphosphate (H2NTP) to form 7,8-dihydromonapterin triphosphate (H2MTP) (PubMed:9182560) (PubMed:9651328).  Is required for tetrahydromonapterin biosynthesis, a major pterin in E. coli (PubMed:19897652).
What are the official names of this protein?
Dihydroneopterin triphosphate 2'-epimerase, D-erythro-7,8-dihydroneopterin triphosphate epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: BABA1_PONAB
Sequence: MEVPEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADDGSPNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLAHPLQRPCQSHASYSLLEEEDEATEVEATV
What is the function of this protein?
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).  The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.  In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs.  Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates.  In these 2 complexes, it is probably required to maintain the stability of BABAM2 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component.  The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression.  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.
What are the official names of this protein?
BRISC and BRCA1-A complex member 1, Mediator of RAP80 interactions and targeting subunit of 40 kDa, New component of the BRCA1-A complex.
What is the protein family that this protein belongs to?
Belongs to the BABAM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: SFSA_VIBC1
Sequence: MQFKPALESATLLKRYKRFLADIELDSGEMRTIHCANTGSMTGCATPGNKVWYSTSDNPKRKYPNSWELSETAQGHRICINTARANQLAVEAIENDVISELVGYDQLQTEVKYGNENSRIDILLSASDKPKCYIEVKSVTLLDEESPSGQGYFPDAVTTRGQKHLRELTEMAQTGSRAILLFTVLHSGIEKVSAAHHIDAKYSTLLKQAQDAGVEVLCYKAELSNTEVKLISAIEFIN
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: CSST1_CONMH
Sequence: MQTASWVMVMMMVWITAPLSEGGKLNDVIRGLVPDDVTPQLILRSLFFHRPSDSVVRSTVPVHICYWKVCPPSPWRRPNGKG
What is the function of this protein?
Moderately activates human somatostatin receptors (SSTR) with a preferential activation of SSTR1 and SSTR4.  In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter.  Four to five hours after injection, mice recover, even with the highest dose tested.  Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system.
What are the official names of this protein?
Consomatin Mao1, ConSST Mao1, Consomatin Ma1, Somatostatin-related peptide, SSRP.
What is the protein family that this protein belongs to?
Belongs to the conotoxin C superfamily. Consomatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRTP_STAAE
Sequence: MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the oxidation of the terminal methyl side group of 4,4'-diaponeurosporene to form 4,4'-diaponeurosporen-4-al.
What are the official names of this protein?
4,4'-diaponeurosporene oxygenase, 4,4'-diaponeurosporene oxidase, Carotenoid oxidase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtP subfamily.
Protein: ASCL3_ORYSJ
Sequence: MAIRGPEASSFFPLTLVFSVGFFCARFFLDRLVYKPLAAYCFSSKASKLMNDEVRQAKIVKFSESIWKLTYYGSVQAWVLLIIKQEPWSLDTMQYFEGWPNQYMTSSLMLFYMCQCGFYIYSIFALVAWETRRKDFAVMMSHHVVTSILIGYAYLTGFFRIGTIILALHDASDVFLETAKLCKYTEKELGASLFFGLFALSWLLLRLIYFPFWIIKTSSYQSIISLRKLEKFPTTLYYIFNTMLLTLLVFHIYWWKLICLMIMKQLNNKGQVGEDVRSDSEDEE
What is the function of this protein?
Mediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis.  Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity).
What are the official names of this protein?
ASC1-like protein 3, Alternaria stem canker resistance-like protein 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IOLB_LISIN
Sequence: MGKLLRKPLNERIAPGVTLVQDINQGNSPLSYVGFRLIELEKGAVYQEALTDLECCIVALTGKITVSEGDDIFAEIGTRANVFEKIPTDSVFISGGRAFQVKADTEKARVALCYSPANRDLPTTLIKASDNSIEQRGKYQNKRLVHNILPDVSGVASSLLVVEVYTNGGNFSSYPPHKHDRDNLPAESLLEESYYHEINPEQGFIFQRVYTDDRALDETMAVEHQNAVIVPEGYHPVGVPDGYDSYYLNVMAGPKRVWKFHNDPDHEWILERD
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.
Protein: RS7_NOCFA
Sequence: MPRKGPAPKRPLINDPVYGSPLVTQLVNKILLDGKKSTAERIVYGALEQAREKTGTDPVVTLKRALDNVKPSLEVKPRRVGGATYQVPVEVRPGRANTLALRWLVNFARARREKTMVERLANELLDASNGLGASVKRREDTHKMAESNRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.