PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_MAGSA
Sequence: MTQDQTAEQMPAAESADQSADQGPAAESAAPPAVDSERIKELEAEIAKLKNDVLYAKAETENTRRRLEQQAEDRGRYAISNIAKDVLSVADNLRRALDSVPASAREGNESLTALTTGVEMTERELLATFERYGIKLVAAQGERFDPNLHQAMMEMEDPSQIEGTVVLVMQAGYTLHDRLLRPALVGVAKGGPKSGGNNVDTKV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCAD1_HUMAN
Sequence: MNGRADFREPNAEVPRPIPHIGPDYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLILACIMGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGQARRSSPPGHYYQKSKYDSSVSGQSSFVTSPAADNIEMLPHYEPIPFSSSMNESAPTGITDHIVQGPDPNLEESPKRKNITYEELRNKNRESYEVSLTQKTDPSVRPMHERVPKKEVKVNKYGDTWDE
What is the function of this protein?
Maintains stem cell potency (By similarity).  Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity).  May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity).  Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946).
What are the official names of this protein?
OCIA domain-containing protein 1, Ovarian cancer immunoreactive antigen domain containing 1, Ovarian carcinoma immunoreactive antigen.
What is the protein family that this protein belongs to?
Belongs to the OCIAD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: EFGM_YEAS6
Sequence: MSVQKMMRVPRKMVGGRIPFFTCSKVFSGFSRRSFHESPLARSTYEEEKVLVDEIKQKLTPDDIERCNKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYCSWDKEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQLNSKLKIPAAAVQIPIGSESSLSGVVDLINRVAIYNKGDNGEIIEKGPVPENLKPLMEEKRQLLIETLADVDDEMAEMFLEEKEPTTQQIKDAIRRSTIARSFTPVLMGSALANTGIQPVLDAIVDYLPNPSEVLNTALDVSNNEAKVNLVPAVQQPFVGLAFKLEEGKYGQLTYVRVYQGRLRKGNYITNVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGIDCASGDTFTDGSVQYSMSSMYVPDAVVSLSITPNSKDASNFSKALNRFQKEDPTFRVKFDPESKETIISGMGELHLEIYVERMRREYNVDCVTGKPQVSYRESITIPADFDYTHKKQSGGAGQYGRVIGTLSPVDDITKGNIFETAIVGGRIPDKYLAACGKGFEEVCEKGPLIGHRVLDVKMLINDGAIHAVDSNELSFKTATMSAFRDAFLRAQPVIMEPIMNVSVTSPNEFQGNVIGLLNKLQAVIQDTENGHDEFTLKAECALSTMFGFATSLRASTQGKGEFSLEFSHYAPTAPHVQKELISEFQKKQAKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOZ_DESHD
Sequence: MKQPSLDILLSKVDSKYTLVLAAAKRARTLMEDPEFEVNYRGSKPVSLAFDEIAKGKYHFELTREGIK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NTPPA_FLAJ1
Sequence: MLKEKLKKYKIILASGSPRRQQFFKDLDLDFEIRLKDVEEIYPPELKAVEITNFLAELKANAFEGELKENEILVTSDTIVWHQNKALGKPKNAEDAFQMIKSMSNTTHEVITSVCFKTNTAFTLLHDVTKVTFKDLSDESILYYIENYKPYDKAGAYGIQEWFGFMAVTKVEGSYTNVMGLPTAKVYEYLTTLV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_NOSS1
Sequence: MTTSAQILPLVKDPERLEARLSEIPPEPGVYFMRDGSDRIIYIGKSRKLRSRVRSYFREGYNKTERIATMAKLVTEIEFIVTDTEAEALALEANLIKQHQPYFNVLLKDDKKYPYVCITWSEDYPRIFITRKRQLGKEKDKYYGPYTDSGLLREILRISKRIFALRQRPQPLFKDRPCLNYDLGRCPGVCQQLISPEEYRKTVQKVAMVFQGRTQELIDILSEQMEKAAEALNFEVAARIRDQIAGLKSLTAEQKVSLPDDTVSRDAIALAGDAQHACIQLFQIRAGQLVGRLAFVAESHAEPGAILQRVLEEHYQTAESVEIPAEILVQHELPDAEILADVLTQLKGRKVTIFTPQRQVKAELIEMVERNAQYELQRMQKLGDRNHQATQDLAAILDLPNLPHRIEGYDISHIQGSNAVASQVVFIDGLPAKQNYRHYKIKNPTVTIGHSDDFASLAEVIQRRFRKYAEDPQLSRVGNPDWPDLIMIDGGKGQLSSVVTVLQEMNLLEDLRVISLAKRREEIFLPGESQPLKTDAEQPGVQLLRRLRDEAHRFAVSFHRQQRSDKLKRSRLDEIPGLGHHRQKQMLAHFRSVDYIRQATPSQIAEVPGIGPHLAQAIYDYFHPSHL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFCB3_MOUSE
Sequence: MAVSEIKATMKLKPLKAPVFHKRDKDLRGSFSDHLKHKESKLSPAQLEAFRNAYNFFTKDRTGCIDSHGLISTIAKLGMNLNTYDIYNELKCADLDRDGKINFSDFINVLTDKKLFLKAVVPEKKICLDLANNPGILLFEILSKFVETSSLHRKDIIELVSYFRKRFQESHSEIMWSSYGRRGLKSEICSPPRSSTAAFANSARISIMKERDLYKFLEALKRCNLRTDSPYSKIPVFPLFPDVDGTVMGKPFKDTQKIEMLRRKEPLTFFEDYFFNKRDWKTQAMNVKPLKSASGYSDDILAIDHLFKKKQHWTVTDAAAIKQHVKKATESYNLGIALDHRKEMLNLWKKIRGDLVGIESNNESFYNTFSTYTWSWNVCQELLSAKDLRLHDASMNKSSPSNSGLSSPSDFSESDPETGRKRKRKSSRGFRQ
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 3.
Protein: ATS3_HUMAN
Sequence: MVLLSLWLIAAALVEVRTSADGQAGNEEMVQIDLPIKRYREYELVTPVSTNLEGRYLSHTLSASHKKRSARDVSSNPEQLFFNITAFGKDFHLRLKPNTQLVAPGAVVEWHETSLVPGNITDPINNHQPGSATYRIRRTEPLQTNCAYVGDIVDIPGTSVAISNCDGLAGMIKSDNEEYFIEPLERGKQMEEEKGRIHVVYKRSAVEQAPIDMSKDFHYRESDLEGLDDLGTVYGNIHQQLNETMRRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFDHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDPKKRCHLYCQSKETGDVAYMKQLVHDGTHCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIESLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAAFRPNSKPDGANLRQRSAQQAGSKTVRLVTVPSSPPTKRVHLSSASQMAAASFFAASDSIGASSQARTSKKDGKIIDNRRPTRSSTLER
What is the function of this protein?
Cleaves the propeptides of type II collagen prior to fibril assembly.  Does not act on types I and III collagens.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 3, ADAM-TS 3, ADAM-TS3, ADAMTS-3, Procollagen II N-proteinase, PC II-NP, Procollagen II amino propeptide-processing enzyme.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: CEEH1_CAEEL
Sequence: MLFESIYIQCLNKFSKYKKFVCHTTCNCPNYKIIGYLLYFLCLCRPINCSLPLSRHDLAFGSFSYYLTMFLYRILVRLLQFYYFVKFSAILFLGFAVKGRSLFEKKQREKPNVLEGWDSRYIKLKKVRLHYVQTGSDDKPLMLFIHGYPEFWYSWRFQLKEFADKYRCVAIDQRGYNLSDKPKHVDNYSIDELTGDIRDVIEGLGYDKAIVVAHDWGGLVAWQFAEQYPEMVDKLICCNIPRPGSFRKRIYTSWSQFRKSWYMFFYQNEKIPEMLCSADDMKMLELCFRAKEIGIQNNKNFTDEDLEAWKYSFSMNGASFKYPINYYRNIFNAKKQQADLVLEMPTLIIWGTADGALDIEAAVDSLNTLKQGTMKKIEGASHWVQQDEPEMVNEHIKKFLNKYQ
What is the function of this protein?
Catalyzes the hydrolysis of epoxide-containing fatty acids.  Active against epoxyeicosatrienoic acids (EETs) including 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate (8,9-EET), 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate (11,12-EET) and 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate (14,15-EET) and the linoleic acid metabolites 12,13-epoxy-(9Z)-octadecenoate (12,13-EpOME) and 9,10-epoxy-(12Z)-octadecenoate (9,10-EpOME).  These epoxides function as lipid signaling molecules, the enzyme can deplete the supply of the epoxide signal by transforming them into diol species that are more readily eliminated through excretion.
What are the official names of this protein?
Epoxide hydrolase 1, CEEH1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PHS_VIBCM
Sequence: MLDELRCEACSAGAIGLTSEEQQQLLSELDGWALIHRDGIAQLEKRYRFKNFKQAWAFSNQIAELAEQEFHNPAILLEWGNVTVTWWSHSIKGLHKNDFICAAKCDALT
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RLUB_YERPE
Sequence: MGEKLQKILARAGHGSRREIEAIIQQGRVSVDGKVSKLGDRVEVTQSTKIRLDGHLLSIKESEENVCRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDDKIKQLSRGVQLEDGPAAFRTISYQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRGGWTELDLKATNYLRELVELDVETVSKLPVEKDRRRVKANQIRRAVKRHTEVSGRQVAGRQGSARKGSTRQNVGNAAPAATASRRSGPKKRG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: JAYE_ECOLI
Sequence: MWYMRWEGVSDGLKVTAGSVIQRDDLVQYTTTDDATSSGGVLRVPIACSSAGAVGNADDGTALILVTPVNGLPSSGVADTLTGGFDTEELETWRARVIERYYWTPQGGADGDYVVWAKEVPGITRAWTYRHLMGTGTVGVMIASSDLINPIPEESTETAARQHIGPLAPVAGSDLYVFRPVAHTVDFHIRVTPDTPEIRAAITAELRSFLLRDGYPQGELKVSRISEAISGANGEYSHQLLAPVDNISIAKNELAVLGTISWT
What are the official names of this protein?
Putative protein JayE, Putative protein JayE from lambdoid prophage e14 region.
What is the protein family that this protein belongs to?
Belongs to the Mu gp47/PBSX XkdT family.
Protein: CYB_GYMRO
Sequence: MTNIRKTHPLLKIINHSFIDLPTPSNISSWWNFGSLLGMCLIIQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFIHVGRGIYYGSYTFTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFMIAALAVVHLLFLHETGSNNPSGLNSDADKIPFHPYYTIKDILGMLLLLLLLMSLVLFAPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKLRGLMFRPITQSLFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFSIILILMPLAGIIEDKILKLS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FACT_ARATH
Sequence: MADSFELIVTRKEPVLVSPASETPKGLHYLSNLDQNIAIIVKTFYYFKSNSRSNEESYEVIKKSLSEVLVHYYPAAGRLTISPEGKIAVDCTGEGVVVVEAEANCGIEKIKKAISEIDQPETLEKLVYDVPGARNILEIPPVVVQVTNFKCGGFVLGLGMNHNMFDGIAAMEFLNSWAETARGLPLSVPPFLDRTLLRPRTPPKIEFPHNEFEDLEDISGTGKLYSDEKLVYKSFLFGPEKLERLKIMAETRSTTFQTLTGFLWRARCQALGLKPDQRIKLLFAADGRSRFVPELPKGYSGNGIVFTYCVTTAGEVTLNPLSHSVCLVKRAVEMVNDGFMRSAIDYFEVTRARPSLTATLLITSWAKLSFHTKDFGWGEPVVSGPVGLPEKEVILFLPCGSDTKSINVLLGLPGSAMKVFQGIMDI
What is the function of this protein?
Involved in the synthesis of alkyl hydroxycinnamates in root waxes.  Functions as a fatty alcohol:hydroxy cinnamoyl-CoA acyltransferase with apparent preference for caffeoyl-CoA.
What are the official names of this protein?
Fatty alcohol:caffeoyl-CoA acyltransferase, Fatty alcohol:caffeoyl-CoA caffeoyl transferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: HLDE_BLOPB
Sequence: MTVIFPNFSKSSVLIVGDVMLDRYWYGPTDKIAPEAPVPIVKVNKIIDRPGGAANVAMNIASLGARSRLLGLTGVDEAAKILKKQLNESNIKWNFISVRTCPTIIKLRVMSRNQQLIRLDFEQYFNNVDTTKLLKQVELYLPKYKVLVLSDYAKGSLNCIEEIIKLARYMNVPVIVDPKGIQFSRYKGATLLTPNISEFESIVGSCRNEKILINRAQEIIIDYNLSALLITRSERGMTLCTRYAAPLYFSTQKKKVYHVTGAGDTVVGVLSAALSSGKSLEKACFLANLAASAVIKKSGTSTSNVTEMKNIMNSHICTTLPVGILDEKTLKQTISVVRNRGEKIVMTNGVFDILHSGHVSYLTNAKKLGDRLIVAVNSDGSTRRLKGKTRPINTLEQRMFILAALTVVDWVVPFYEDTPSRLVAYLSPDFLVKGGDYHVCDIEGSQGVLNRGGTVRVLNFQTGCSSSNIINAIKRKN
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RS13_CAUSK
Sequence: MARIAGVNIPTNKRVLIALQYIHGIGQKSARDIVTKVGIDDARRVNQLTDAEVLAIRETIDKDFTVEGDLRRENSMNIKRLMDLACYRGLRHRKGLPVRGQRTHTNARTRKGPAKPIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ILVH_HAEIN
Sequence: MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQIEKQLHKLVDVFKVVNLSEQEHIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSYTIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEKNIL
What are the official names of this protein?
Acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: KLF2_HUMAN
Sequence: MALSEPILPSFSTFASPCRERGLQERWPRAEPESGGTDDDLNSVLDFILSMGLDGLGAEAAPEPPPPPPPPAFYYPEPGAPPPYSAPAGGLVSELLRPELDAPLGPALHGRFLLAPPGRLVKAEPPEADGGGGYGCAPGLTRGPRGLKREGAPGPAASCMRGPGGRPPPPPDTPPLSPDGPARLPAPGPRASFPPPFGGPGFGAPGPGLHYAPPAPPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWPRKRTATHTCSYAGCGKTYTKSSHLKAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRHM
What is the function of this protein?
Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription (PubMed:21063504).  Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements (PubMed:28167758).
What are the official names of this protein?
Krueppel-like factor 2, Lung krueppel-like factor.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NS12_CVHN1
Sequence: MDVWRPSYTHSLVIREFGVTNLEDLCLKYNYCQPIVGYCIVPLNVWCRKFGKFASHFTLRSHDISHSNNFGVVTSFTTYGNTVSEAVSRLVESASEFIVWRAEALNKYG
What are the official names of this protein?
Non-structural protein 4, ns4, Accessory protein 4, Non-structural protein of 12.5 kDa, ns12.5, Orf4 protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.
Protein: DAPA_PELPD
Sequence: MFKGSIVALVTPFRDGAVDEETLRRMVDYQIENGTDGISPCGTTGEASTLDYDEHMRVIEIVIQQVNGRVPVIAGTGSNSTTEAIELSRKAKKLGADGVLLVSPYYNKPSQEGLYRHFRAIADAVDIPQVLYNVPGRTGVNMLPQTVARLAEHDSIVAIKEATGSLQQASELMEMCGDKIDVISGDDFITFPMMACGATGVISVVANIMPREVARLVDAFYEGDMDEARRLHLSLLNISNAMFIETNPVPVKTAAALMGLCAEELRLPLAPLGDASRATLCAVMKSYGLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_MESFL
Sequence: MTKFRLRYAPSPTGFLHIGNTRTALMNYLFAKHYNGDFIVRIEDTDLERNVEGAIESQFENLNWLGINADESFLKPGEEKYGKYMQSQKFGRYQELAEKLISIKKAYRCFCTTEELEKDYEDQVAKGIVATKYSGKCSRLSESEIESNLKSNKDFSIRFLVPETTLNIKDFIKGEITFDSKELGDFVILKTNKIATYNFAVVVDDFDMEISHVLRGEEHISNTPRQILIYQAFGWETPQFGHMSLIVDSTGKKLSKRSGNALFFIEQYKNQGYLPEAMFNYISLLGWSPIGEKELLTKQELISMFDDKRFSKSPSTFDMTKMKWINSQYMKALSEEEYLEFTKKYINTEMFNTKEKSEDWLNQVLLLFKKELEFADQINNHLNIFFNEVDVTSETIEILKTIEEHESVIKEFETQISTLNEWEIENIKSLIKLVSENTGKKGKDLFMPIRIASSSSEHGPSLADVIYLLGKDKVLANIAKVK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMN3_HUMAN
Sequence: MATRRFSCLLLSTSEIDLSVKRRI
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 3, HN3, MT-RNR2-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: GLMU_BURMS
Sequence: MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELRIDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSKAQLAELERIHQRNLADALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANAVVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_YERP3
Sequence: MFDVLIYLFETYMHNEPEMLVDQDKITDDLADAGFYREDINNALNWLEVLADLQEGQKAPYLYTADPQALRIYTVEECRRLGAACRGFILFLEQIQVLQFDTREMVIDRIMALDSPEIDLEDLKWVVLMVLFNIPGYENAYKQMEELLFEVNDGYLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: LON3_SORC5
Sequence: MFFKNDSDRGKNAPERGIVPLLPLRDIIVFPHMVSQLFVGRERSIAALDEAMNRGKEIFLAAQRNAKTNDPTPDDIFGVGSVGAIMQLLRLPDGTVKVLIEGKRRARIRRYVQSDAYFLIEYDEIVESSVASVEVEALMRSVQSTFEMYVKLNKKIQPEVLMAVQAIDEASRLADTIIANLPTIKLTDRQALLEMEEPQKRLERLIELMQAEIEILQVEKKIRSRVKKQMEKTQKEYYLNEQMQAIQKELGGGERDEFKNEIQEIEEALKTKRMSKEAAAKVKKELKKLKMMHPTSAEATVVRNYIDWILELPWYDKSEERYDLVEAERILDEDHYGLKKIKERILEYLAVQALTKKLKGPVLCFVGPPGVGKTSLAKSIARATGRKFVRLSLGGVRDEAEIRGHRRTYIGALPGKLIQSLKKVGTNNPVFLLDEVDKMSTDFRGDPAAALLEVLDPEQNHTFNDHYLDLDYDLSDVMFITTANTLSGIPVPLQDRMEVIQLSGYTEFEKLNIAVKYLVPRQRKECGLEDVSLDFTEGALRTIIHHYTKESGVRSLEREIASVCRKVARRVVSDGKEKPIEVVAKSIPKYLGVPKYRLGRREERDEVGLVNGLAVTNVGGDLLPAEATVVPGKGKLVITGLLEKGMEESGHAAMSYVRSRLDRLGLEADVYQKVDVHIHFPDFVRKDGPSAGVTMVTALVSSLMKVPVRRDLAMTGEITLRGRVMPIGGLKEKLLAAHRGGIATVILPKENRKDLRDVPRRVLKALRLVLVEHVDDVLREALILPDAYAIFGPPKGVLEYRDGELVTEAAPVKAPPAAAGEPTPAAPPGA
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease 3, ATP-dependent protease La 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HECAM_MOUSE
Sequence: MKRERGALSRASRALRLSPFVYLLLIQPVPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDKPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRVLMEDDDLYSCVVENPISQVRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKKSRKKRKLEKQNSLEYMDQNDDRLKSEADTLPRSGEQERKNPMALYILKDKDSSEPDENPATEPRSTTEPGPPGYSVSPPVPGRSPGLPIRSARRYPRSPARSPATGRTHTSPPRAPSSPGRSRSSSRSLRTAGVQRIREQDESGQVEISA
What is the function of this protein?
Involved in regulating cell motility and cell-matrix interactions.  May inhibit cell growth through suppression of cell proliferation (By similarity).
What are the official names of this protein?
Hepatic and glial cell adhesion molecule, glialCAM, Hepatocyte cell adhesion molecule, Protein hepaCAM.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass type I membrane protein; Cytoplasmic side. Note=Colocalizes with CDH1.
Protein: RL35_ECOBW
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.