PharMolix/UniProtQA huggingface dataset:
Protein: Y1589_METJA
Sequence: MMMALQIFIKILPIMFFGILLANLMCHLNILYKLQKYIKNKYFPIIAVFFVSSTSGSFLLKNLLKKGEISEENLLPIYFLGMFVFGIHIILFYAIPMATSLGWYVGGIYVLIKFLVTCNYLIISVLMLKKRKYNIDIEFKSKSEGLYGAIRDTFKQYFRVLTSFVPSVLIITYLIEHGLLDIVEDFAGSLLNALNLSPTILVIVLTGLATISGAIGIASGLLDENILSPNEVLFSLFLAGF
What are the official names of this protein?
Uncharacterized protein MJ1589.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0871, MJ0880 and MJ1556.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CWP37_TOBAC
Sequence: VTVGHVF
What are the official names of this protein?
10 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: YK01_SCHPO
Sequence: MSGSCQFLSRETLSSSLGWIPLINALREIFTENVVCPTRLHYPIDEDNPSSTANNILLIMPCWIPGKFLGVKQVNVFPENTKHGLPSLSSHYLLSDATTGCHLAQLDGNELTSRRTAAASALASSYLSKEDSTSLLIIGSGKVAEKLIHAHCSVRPIRSVRIWNHRFESAKSLASRASKELPSIQIDAVPIQNLENAVKCSDIISSATLSKKPIIVGSWINPGTHIDLVGGFTPHMHEADSKCIQISNVFVDTRKGALHEAGDLLTPIKEGLFSPNEVIADLFDLCNNKHSGRSQLKNPAEAITLFKSVGDSREDLAAASLAYKVHNKSS
What are the official names of this protein?
Uncharacterized protein P11E10.01.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_SALEP
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPE_PARDP
Sequence: MTPIPDPAQLTARLIRCASVTPDEGGALVLLADVLGAAGFECHRVDREGVPNLFARWGAQGARTFGFNGHTDVVPPGDPASWTHPPFSGHEAEGWIWGRGATDMKSGVAAFAAAAIGFVTQTPPPDGAVILAITGDEEGPGKHGTRALLDWMAARGERMDVCIVGEPSNPDRMGEMIKIGRRGSMTLQIEAHGIQGHAAYPHRARNPIHALLRLLHELTDAPLDEGTEHFDPSGLQVTTVDCGNPASNVIPERARAVINIRFNDAHTAESLDRMIRARAAAISAETKVDFAISTDVSGESFLTAPGPFVDLVAGVVREETGLDPVLSTSGGTSDARFVKDHCPVLEFGLVGHFMHQVDERVPADQVRQLARIYRRILERYFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RL6_RHOCS
Sequence: MSRIGKHPVPVPAGVTVTVAGQNLTAKGKLGQLSLSLIDDIAVSMEDGKVVVQPRTETKRARQNWATARTLVFNLVKGVNDGFTKNLEINGVGYKAAVQGKDLVLNLGYSHEIRYPIPEGITIKCDKPTSVSVSGTDKQQVGQVAAEIRAFRGPEPYKGKGVKYENEVIIRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PTAS_HELPJ
Sequence: MQSLWIYPEDTEVLGAACKSLLKALKPRYQKIALFSPISGGCEGFGECESLSSLEVHSAIDKQKALELVSTAQEELLFETILKRYDELQSTHDFVINLGYAPKFFLNALLDLNTILAKHLNAPVVAVAQTSLDHLKAMHSHILKKEAPFAIGLFVGETLEKPHFLSASLCKQQCELEASAIENLLQTKSEIITPLAFQRSLEKKAKKQIKKVVLPESEDERILKAAHRLNLMGAVGLILLGDKEAINSQAKNLNLNLENVEIINPNTSHYREEFAKSLYELRKSKGLSEQEAERLALDKTYFATMLVHLGYAHAMVSGVNHTTAETIRPALQIIKTKPGVSLVSSVFLMCLDTQVFVFGDCAIIPNPSPKELAEIATTSAQTAKQFNIAPKVALLSYATGNSAQGEMIDKINEALTIVQKLDPQLEIDGPLQFDASIDKGVAKKKMPNSQVAGQASVFIFPDLNAGNIAYKAVQRSAKAVAIGPILQGLNKPINDLSRGALVEDIVNTVLISAIQAQDY
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_AZOSB
Sequence: MPNIKLPDGSVRSFDHPVTVAEVAASIGSGLAKAALAGRVDGKAVDLSYCIERDSELAILTDKSAEGVDVIRHSTAHLLAHAVKELFPEAQVTIGPVIENGFYYDFSYKRPFTPEDLEAIEKRMAELVKRELPVEREVWPRDKAVAFFKSIGEHYKAEIIASIPANEDVSLYRQGEFVDLCRGPHVPSTGRLKVFKLTKLAGAYWRGDAKNEMLQRVYGTAWAKKEDLESYLHMLEEAEKRDHRKLGRQLDLFHIQEEAPGMVFWHAKGWTLWQQVEQYLRGTISRHGYQEVRTPQIVDRSLWEKSGHWGMYSDLMFTTQSEKHDYAVKPMNCPCHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGIMRVRNFVQDDAHIFCTDEQVQEEAAAFIALLQKVYADFGFRDIQIKLSTRPEKRVGADEQWDAAEAALAAALKAQGLEYELQPGEGAFYGPKIEFSLKDCLNRVWQCGTLQLDFNLPVRLGAEYVAEDNTKKFPVMLHRAIVGSLERFIGILIEHYAGAMPLWLAPVHAVVMNISEGQADYATEVVNRLREAGFRVEADLRNEKINYKIREHSVHKLPYQLVVGEKEKAAGVVAVRVRGGQDLGQLSLDKLIERWNGELASRSGPV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP1_ACTPL
Sequence: VTVYDAEGTKVQIDGSLRVEL
What is the function of this protein?
Structural rigidity of the outer membrane of elementary bodies and porin forming, permitting diffusion of solutes through the intracellular reticulate body membrane.
What are the official names of this protein?
40 kDa major outer membrane protein, MOMP.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: METK_STAES
Sequence: MTYNKRLFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTTTYVDIPKVVRETIKDIGYTRAKYGYDSQTMAVLTAIDEQSPDIAQGVDKALEYRNDISEEEIEATGAGDQGLMFGYATDETDTYMPLPIFLSHQLAKRLADVRKDEILDYLRPDGKVQVTVEYGEDDKPRRIDTIVVSTQHAEDVELAQIEKDIKTHVIYPTVDKALLDDETKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAKQCEVQLAYAIGVAEPVSISINTFDTGKVSEARLVEAVRKHFDLRPAGIIKMLDLKQPIYRQTAAYGHFGRTDVLLPWEKLDKVNVLKDAVEIQ
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_ECOLI
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase, Quinolinate synthetase A.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOP1_DICDI
Sequence: MNKSKVTSKKVVAETKVVNNKKSEPIAVSEPKKSVSKPTTTATTTVSKSPVSTITTQILGKRTKTPVVRDEENEDEKLDFGNIDLNNYNSEDDEDYESEEDDEGDDEEDVESQNGSIVYSESEEEEEGGINKALLEAEESLVEYQSEDDSGSISSKSSSSTTTTTTTTKKTNNDEEEVAPNKQWTNDPNQFYDSDDSSEDESLVNRIGNIPLEWYDDYDHIGYDVDGNKIMKTESMKDSIDKYLDQQDPNFWRTVYDKVNDKKVVLSDDDMALLKSIQNKHFIPGYDPYADWYDSGNNHPDSIHPMHNAPVPKRSFFPNGTDEEREIRRLTKAIRMGWIKLNKKGKKGEKDKKDGNFDLWADEGEEKEKTKGIRRIAAPKQKLPGNVESFNPPEEYLLNENELKAWHLMDPRERPHNFIPQKYQSLRQLPIYNKLIKERFERCLDLYLCPRTTRVKQFTKDPTKFLPTLPKPQDLRPFPSHEEIQFLGHKARVRSISISPNGQWLASGSDDCTIKIWEVSSTRCLYSLEVESEVQTVAWNPNPIYNILAVGYSNKIIIITPPLFGTQTEHSPETEKILTKPPTDSSTEQQQNKSVNWYQVTGADKAKLLEKGVRIEIHHPFTVKNLTWHYKGDYFSTTSPEEGTRSVKIHHLSKRATQSPFRKSKTPNQVTRFHPNKPIFFVADQNIIRVYDLMKQELIKKLITGCRYISSIDIHPQGDNVIMGGYDKKVCWFDLDLSVRPYKVLNYHKMAVRKVIYHPTLPLFASCSDDLSIHVFHGMVYDDLLQNALIVPLKILKTHESINDLGVLDIVFHPKQPWIFSSGADSTIRLYTN
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: NADD_CELJU
Sequence: MRPTLGLFGGTFDPIHIGHLRLALELKQQLQLDGMRLMPCHLPAHRDQPGASSTQRATMLQLALAACPELSIDLREVARARASYTVDSLSELRAELGAETSLVFCLGTDSFAGLDRWHRWQELLQLAHLVVVERPGWDIPSTGPVRTLLAQHQGAPGQLRLAACGSIVRLAPRLLPISATEIRQLIGAGQSPQFLVPDSVWQYIGQERLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: HKS_HELHO
Sequence: GPPYQPLVPR
What is the function of this protein?
Helokinestatin antagonizes the vasodilatory actions of bradykinin at the B2 bradykinin receptor (BDKRB2) in a dose-dependent manner.
What are the official names of this protein?
Helokinestatin-1, Helokinestatin.
What are the subcellular locations of this protein?
Secreted.
Protein: GH_BHV1C
Sequence: MRRPLCAALLAAAVLALAAGAPAAARGGAGGRSREHRDARYEIEEWEMVVGAGPAVHTFTIRCLGPRGIERVAHIANLSRLLDGYIAVHVDVARTSGLRDTMFFLPRAAVDNASAADIPDTPAVQSHPGLFGAAFSWSYLQTRHLVDYDLVPSRPLQDWYFSQARAESNAARPPPAPRVTPTPAGRVAAFDINDVLASGPEHFFVPVRADRKRRERHVADFAAVWPVSYIPAGRAVLSCERAAARLAVGLGFLSVSVTSRDLLPLEFMVAPADANVRMITAFNGGGAFPPPGPAAGPQRRAYVIGYGNSRLDSHMYLTMREVASYANEPADFRAHLTAAHREAFLMLREAAAARRGPSAGPAPNAAYHAYRVAARLGLALSALTEGALADGYVLAEELVDLDYHLKLLSRVLLGAGLGCAANGRVRARTIAQLAVPRELRPDAFIPEPAGAALESVVARGRKLRAVYAFSGPDAPLAARLLAHGVVSDLYDAFLRGELTWGPPMRHALFFAVAASAFPADAQALELARDVTRKCTAMCTAGHATAAALDLEEVYAHVGGGAGGDAGFELLDAFSPCMASFRLDLLEEAHVLDVLSAVPARAALDAWLEAQPAAAAPNLSAAALGMLGRGGLFGPAHAAALAPELFAAPCGGWGAGAAVAIVPVAPNASYVITRAHPRRGLTYTLQGIDVANPLLVTFVRGTSCVSASGAVEARRLAVPGPLDACAYCGSVFVRYLPSGAVMDIVLIADKRTEVEFSRGANSSMPVFNPRLHSGRSRAMLLFPNGTVVSVLAFAGHEAPTFSPAYVWASVGGALVAGTTIYAIAKMLCSSVPLARGYSSVPVF
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: MTLD_ECO7I
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAAHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: NUOB_RICB8
Sequence: MHNNFYQEDELLNNELSNRGFLLTKVDDVIGWARSNSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARKNH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UREE_HELBI
Sequence: MLAESVLGNLKEGGSSKELDFIDLEWFDAQKRMGRFTSQKGAELVLKLKNPPKMGLCDGDILFEDATSLIAINIIPTPTLHVYADSTAQVARLCYEVGNRHASLYYGDSPLSFKTPFERPLQVLFDKLALRYEVLKSKLDASQRISVSAPHADPLQEGSAPLKFKSALDLQIVIKK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB4U_HETPE
Sequence: MKTQFAILLITLVLFQMFSQSDAILGEIWKGIKDILGKRGLNDLSDLDELFDGEISKADLDFLREIM
What is the function of this protein?
Amphipathic peptide with antimicrobial activity (By similarity).  Does not show antiviral activity (PubMed:24315793).
What are the official names of this protein?
Peptide Hp1165.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: RSSA_HYDVD
Sequence: MSEGIDALSLKEEDVVKFLAAGVHLGSTNVGSSCQGYVFKRKSDGIHIINLRKTWEKLILAARIIASIENPADVCVISSRPYGTRAVLKFAQSTGAIPIAGRFTPGTFTNQIQKRFREPRLLISTDPQHDNQALTEASYVNIPVIALCNTDSPLRFVDCAIPCNNRGIQSIGTMWWILAREVLHLRGIISRKTPWNVMPDLFFYRDPEDIEKEEQAAAIASAKPDEPYQPDFSGNVDQSAAGADWGDQPVVTGADWTAEPSVSKDWAAEPAGWEADTTAVSGDWATPKTEDWA
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA, 33 kDa laminin-binding protein, p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAA12_ARATH
Sequence: MRGVSELEVGKSNLPAESELELGLGLSLGGGAWKERGRILTAKDFPSVGSKRSAESSSHQGASPPRSSQVVGWPPIGLHRMNSLVNNQAMKAARAEEGDGEKKVVKNDELKDVSMKVNPKVQGLGFVKVNMDGVGIGRKVDMRAHSSYENLAQTLEEMFFGMTGTTCREKVKPLRLLDGSSDFVLTYEDKEGDWMLVGDVPWRMFINSVKRLRIMGTSEASGLAPRRQEQKDRQRNNPV
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA12, Indoleacetic acid-induced protein 12, Protein BODENLOS.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPKG_BOVIN
Sequence: MMEVESSYSDFISCDRSGRRNAVPDIQGDSEAVSVRKLAGDMGELALEGAEGQAEVGTSDKEASSQPESSDGTTSS
What is the function of this protein?
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
What are the official names of this protein?
cAMP-dependent protein kinase inhibitor gamma, PKI-gamma.
What is the protein family that this protein belongs to?
Belongs to the PKI family.
Protein: CHEB3_LEPIC
Sequence: MIQVFIVDDSAVVRQVLTQILNKDPEIEIIGFASDPIFASEKLSSVWPDVFILDIEMPRMDGISFLKKIMSEKPTPVIICSSLAEKESETAVLAMKLGAVDIIEKPKVGLKNFLEESEILFIDSVRAASNARVKTHSFQNDDSKFLENHKQPKTDFSKIDTTDKLIAIGTSTGGTQALEFILTQLNIHCPGIVIVQHMPEKFTEAFANRLNQVCKIQVKEAKDGDRVQLGSAYIAPGNKHMEIYLSGAQFHIRVLDGPLVNRHRPSVDTLFHSVAKAAGKNAKGIIMTGMGNDGANGLLKMKQSGAHTIAQDEASCVVFGMPKEAILKGAVNTILPLSKIVGEVQYF
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_SYNR3
Sequence: MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDPASRVACETVVNTGLCIITGEVTTTARVDFNTLVRGVIADIGYSSAKAGGFDANSCAVLVALDQQSPDIAQGVDEADDHAGDPLDKVGAGDQGIMFGYACDETPELMPLPISLAHRLARRLAEVRHNGTLGYLLPDGKTQVSVVYEDDQPVAIDTILISTQHIAEIDGISDEKGLRERISADLWTHVVEPATADLSLKPSKDTTKYLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARFVAKALVAAGLARKAEVQLSYAIGVAKPVSILVESFGTSSHSNDELTELVNANFDLRPGAIIENFKLRNLPQQRGGNFYREVAAYGHFGRSDLNLPWEDVSVIAAKLKG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R43_HUMAN
Sequence: MITFLPIIFSSLVVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFNSVEVRTTAYNIWAVINHFSNWLATTLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACHLFVINMNEIVRTKEFEGNMTWKIKLKSAMYFSNMTVTMVANLVPFTLTLLSFMLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVISFLLLCAIYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVFWQMRYWVKGEKTSSP
What is the function of this protein?
Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  Activated by the sulfonyl amide sweeteners saccharin and acesulfame K.  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.  May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 43, T2R43, Taste receptor type 2 member 52, T2R52.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: ZD16B_DANRE
Sequence: MRSWRWSVSRIMRLFLRWFRLCPRRGHRKRSRVRDLWNYGMVVLKSLYYNVQTNSDTVLDCMFEPIYWLVDNMTRWFGVVFVCLVMALTSSVVVIVYLCVLPIIFSSYPVYWILWHLCYGHWNLLMVVFHYYKATTTQPGFPPQEKTDIPTVTICKKCIVPKPARTHHCSICNRCILKMDHHCPWLNNCVGHFNHRYFFSFCLFMTMGCVYCSISAKDMFLDAYNAIESGRYKGGASQGEAVPGAGLIYISFQHQSSYQTPPPAFTHQERMVHKSLVYLWVLTSSVAVALGALTLWHAILITRGETSVERHINRKERRRLKLRGKLFRNPYHHGRINNWRIFFGVEKGSDWLWRVLLPSTHPPLGDGLTWDCPAYKSSTTAI
What is the function of this protein?
Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development.  Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC16B, Zinc finger DHHC domain-containing protein 16B, DHHC-16B.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL2_PETMO
Sequence: MALKQYKPVTPSRRYMTTSDFSELSKVEPEKSLLEPLKKTGGRNHYGRVTMRHRGGGHKRKYRIIDFKRDKINIPAKVASIEYDPNRSARIALLVYADGEKRYILSPKGLHVGETVMSGAKAEIKVGNSLPLENIPLGTLVHNIEFEPGRGGKIAKSAGTYAQLMAKEGKYALLKMPSGELRRVRLSCMATIGVVGNEEHSNEVYGKAGKTRWLGRRPKVRGMVQNPVDHPMGGGEGRSKGHIPKSPWGTPAKGYKTRRGKKQSDKFIVRRRVK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CLPX_SYNS3
Sequence: MAKFDAHLKCSFCGKSQEQVRKLIAGPGVYICDECIDLCNEILDEELIDAQGNPRHGAEPSKKTAAGGTRKTSKPAPTLATIPKPQEIKGFLDEQVVGQEAAKKVMSVAVYNHYKRLAWQGDGQGEAAQTATRLHKSNILLIGPTGCGKTLLAQTLAEMLDVPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEQAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFVGLDDVVQKRMGRNAIGFVPNDGRGRNRATRDIQAAQVLRHLEPDDLVKYGLIPEFIGRMPVSAVLEPLDEHALESILTEPRDALVKQFSTLLSMDNVQLDFEAQAVEAIAKEAHRRKTGARALRGIVEELMLDLMYELPSDQNVTAFTITKAMVEEHTGGKVLPLPGTKQHKESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.