PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_LIGS1
Sequence: MAKSKPKDNALAQNRKARHDYNILETYEAGIALTGTEIKSVRASRINLKDGFAQVKNGEVWLMNVHISLYDQGNIFNHDPLRNRKLLLHKKEIKHLSEETQKKGITIVPLKVYIKNGFAKVLIGIAQGKHVYDKRETIKRRDQEREIRRTLKNYG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL10_SYNJA
Sequence: MGKQPLAKKAEMVDEVRSLLQASQMVLVIDYRGLTVSEMNQLRAELRKADAVCMVVKNTLMRRAVADQKAWAGILPFLSGPTAFIMIRGDIPAALKAYQDFAKQTKKTEFRGAAAEGLSLTLDQAKAIAELPPKEVLMAQVAGSLKSVATRLAVGLNAVPTQVARGIQEIPASLARAIRAIADKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PAT_KLEP7
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAAIKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDINAMRTMLSECKKTGDDVAAVILEPIQGEGGVILPPTGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLTQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLMAIEFVDNEIGYDFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTLEQCEQVLKAARKALAALRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: TRPC_STRPS
Sequence: MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDRLQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREISSQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLVETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTGQDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: YR822_MIMIV
Sequence: MFVYPLLISSILNMDMITSFISQHPKYNFLHYLNSGQNGSRQNLTNQIILLEKQTKIPTIAMYVFTKIFDNKIWEIPTNELCQGLVILFGKLGIKKINELAAGNGLLSARLKYFATKMNYVLDIDTSDGTNKMFGKHPFTFVPVREMNIRCYDKSEPIIISWLHCQFEDELLKSIKKHKQDYIFLIGDYPDSGGYNNTHSRHFHSKITSYKYGYWYKVISFNQLSQMDYFINDKIRKDMFVDCRTCVTLYYRIDREYNVAHIVSAVDSVQYEYPNLFGNYMDKNKEYYDQDWTVIKSTDNTIKNYMKNDYQGLDSIIIDGLKPYAEDKFCFERVNMFRIKRTDFDDVMDLFPIGMLNRQSQWSLPGYRRSPLSATAIASAYDSDIDPYTPSKIISKMFEDTSKIENEFIEHGSAQENSEMIHLKFATQLYSMMMQVHLSIMMSEQPLIMMPEQSSDMIDPFLNIIEPYWHTPLIEQKVLRAVRFSGHRIIDFDNNVLCSENYLVGQDINQKLDKNIYFSKRSYIDYPFGESQYFRDIETVYNILKRQDKLTKKIDNNRIFITNYPKHNRNHKTISRRTRYH
What are the official names of this protein?
Uncharacterized protein R822.
Protein: ADE_SINFN
Sequence: MTAHLKKAELHCHIEGATPPELALRQARKYSVDTSAIIRDKAYVWEDFTSFVRCYDSVASLFRTQGDYALLAETYLTELAEAGTIYSEIIVSPDHGNTIGLGADAYLEGLAAGMEAAKAKTGIESRMLITGIRHLGPESVAKTAEYAAMRRHPLVTGFNLAGEERMHSVAEFARAFDIVRDAGLGLTIHAGELSGAFSVRDALDHVRPARISHGVRAIEDADLVKRLAEEGVVLEVCPGSNVSLQVFADFASHPLRPLYEAGVRVTLNSDDPPFFHTSLAQEYEVAAHVMGFSDSDIDRMTKTAIEAAFVDEPTRERLLAALHV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: RL34_MYCPN
Sequence: MKRTYQPSKLKRAKTHGFLARMATASGRKVLKLRRKKQRAQLTVSSER
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DAPAT_ORYSJ
Sequence: MAASPAAGAAAATVSSFVSPSSFSSVKASKPDRLRPARRAAAVNVRCVSSPPATETSFKTKVPRNANMAKLQAGYLFPEIARRRAAHLLKFPDAKIISLGIGDTTEPIPDVITNAMAKRAHALSTVDGYSGYGAEQGEKKLRAAIAATYYADLGIEETDIFVSDGAKCDISRLQVLFGSNVKIAVQDPSYPAYVDSSVIMGQTGLYQEDVQKYGNIEYMKCSPENGFFPDLSSVPRTDIIFFCSPNNPTGAAASRDQLTKLVKFAKDNGSIIVYDSAYAMYISDDSPKSIFEIPGAKEVAIETASFSKYAGFTGVRLGWTVVPKELLFSDGHPVAKDFNRIVCTCFNGASNISQAGGLGCLSPEGLKAMSDVVGFYKENTKIIVDTFTSLGFNVYGAKNAPYVWVHFPGRNSWDVFAEILEKAHVVTTPGSGFGPGGEGFVRVSAFGHRENIIEAARRLKQLYK
What is the function of this protein?
Required for lysine biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E. coli (By similarity).
What are the official names of this protein?
Probable LL-diaminopimelate aminotransferase, chloroplastic, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNFH_ECOHS
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: FUMC_CHLMU
Sequence: MRQENDSLGIVMVPEDKLFGAQTGRSKNFFSYGKELMPIEVIQALVKIKKCAAKANGDLQCLDAKRRDMIVAASDEILSGGLEEHFPLKVWQTGSGTQSNMNVNEVIANLAIKRHGGELGSKNPVHPNDHVNKSQSSNDVFPTAMHIAAVQSIKGSLIPALEHLQKNLDAKALEFSRDIKIGRTHLMDAVPMTLGQEFSGYSHQLRSCLERIGFSLTHLYELAIGGTAVGTGLNVPEGFVDKVIYYLRQETGEPFIPASNYFAALSNHDALVQAHGSLAVLACSLIKIATDLSFLGSGPRCGLGEIFFPENEPGSSIMPGKINPTQSEALQMVCSQVIGNNQSVIFSGTKGNFELNVMKPVIIYDFLQSVNLLSGAMRSFADYFVSGLKVNRGQLQQNVERSLMLVTALAPVLGYDKCSKIALKAFHENLSLKEACVSLGFLSEQEFDTHVVPGLMLGKRERE
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCDB1_RAT
Sequence: MASSTTPVSFLAPPLEQLRHLAEELRSLLPRVRVGEAQETAEEFNREMFWRRLNEAAMKVSGEATVLTTLFSKIPSPSPQETQRICEQVHIATEEVIAAYYTFPKDQGITLRKLVRNAVLDIVDGTAQLLDALLAAPSQSPENGDLISCNSVSVACQQVAEIPKDNKAAALLMLTKSVDLVKDAHEEMEQAVEECDPYCGLLDDSEDNSDSHHNEDGVGLPSNRDSYWSEEDQALITPCLALVRASRASLKKIRILVAENGRKDQVAQLDDIVDISDEISPSVDDLVLSVYPPVCHLTVRITSAKLVSVLIKALEITKASHVSPQPGDSWIPLLINAVDHCMDRIKELTQRAVEL
What is the function of this protein?
May negatively regulate cell cycle progression.  May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity).
What are the official names of this protein?
Cyclin-D1-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the CCNDBP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ZO2_HUMAN
Sequence: MPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFECEKETPQSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEKGLIPNKSRAEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVVSVSTKFPAYERVLLREAGFKRPVVLFGPIADIAMEKLANELPDWFQTAKTEPKDAGSEKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKTMRQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATINLNSANDSWFGSLKDTIQHQQGEAVWVSEGKMEGMDDDPEDRMSYLTAMGADYLSCDSRLISDFEDTDGEGGAYTDNELDEPAEEPLVSSITRSSEPVQHEESIRKPSPEPRAQMRRAASSDQLRDNSPPPAFKPEPPKAKTQNKEESYDFSKSYEYKSNPSAVAGNETPGASTKGYPPPVAAKPTFGRSILKPSTPIPPQEGEEVGESSEEQDNAPKSVLGKVKIFEKMDHKARLQRMQELQEAQNARIEIAQKHPDIYAVPIKTHKPDPGTPQHTSSRPPEPQKAPSRPYQDTRGSYGSDAEEEEYRQQLSEHSKRGYYGQSARYRDTEL
What is the function of this protein?
Plays a role in tight junctions and adherens junctions (By similarity).  Acts as a positive regulator of RANKL-induced osteoclast differentiation, potentially via mediating downstream transcriptional activity (By similarity).
What are the official names of this protein?
Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
Protein: RL34_ECOSM
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PG050_VARV
Sequence: MSKILTFVKNKIIDLIKNDQIKYSRVITIEESDSLLSVNEVYANHGFDCVEMIDENIINENLEQYKTDSFLQ
What are the official names of this protein?
Protein OPG050, Protein F6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG050 family.
Protein: ASPA_PROMT
Sequence: MKQLQVLLVAGTHGNEINGIWLFDEWKKSSFLINTHGIKTFKVIGNPEAKKAGKRYIHHDLNRSFKEESFIKINPLNCERTRASELVNLYGEAGENPCQIALDFHTTTASMGSCIVVYGRRDADLALASLIQNQLGLPVYLHESDQKQTGFLVESWPCGLVVEIGPIGQGLLNSRIISQTKLILETLMEQIHEVKNLNLFFPNKLIIHRHIKSIDFPRDEEGNIDGYVHSLRQSKDWQELKKNDELFCKLNGEIIRFEEDEPYIPVFINEAAYVEKNIAMSFTKRELWNFKKEWKQALIDLIHQK
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: RL16_BURM9
Sequence: MLQPKRRKYRKEQKGRNTGIATRGNAVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEELAREAFRLAAAKLPLKTTFIVRQLGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HISZ_SYNP6
Sequence: MVHQPPAGTRDLLPQDVTQKRWIESRLQQVFQQWGYQRIITPTLERLDTLVAGGAVQRSAVIQVQSDEESGLGLRPELTASIARAAVTRLAGSSLPLRLYYLANVFRPAFQGDRLQQRELFQAGVELLGVGGTLADAEVLHVLADALAELGFGQPPLGSWHLVVGEASLTRSLLQPFPKDLREKVRQAIAQLDRVTLESLPLESQLRDRALLLHDLRGQPDQVFAKLQQLTLTPLEQTLRDRLAQLVELYNASAGPQDSPLLLDLSLLRSFDYYTGIVFEVVYETPTGPWVLAQGGRYDRLLDVYDPQAAGQPGIGFSCNIENLQQVLLAANRLPHRPPAIDQLVIPVDSEAYGAALAEAQRLQRQDQLRVELYLDSDRRPEVVQAFAQRRRIGRIVWVSSGSAPQSEAVAVAERATTTC
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUR_ECOL6
Sequence: MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.  Regulates the expression of several outer-membrane proteins including the iron transport operon (By similarity).
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_BUCAT
Sequence: MNIIQSGITAENSSIAIIIARFNEFINKNLLLGALDTLKRIGQVHEENILKIYVPGTYEIPTIASYIAKSGKYDAIIAIGTIIKGQTDHFKYIANDTSSSLSRISTQYFLPITLGILTTKNIEQSIERSGTKMGNKGSDAALAALEMINVMKKLKKVIYY
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SEY1_PLAVS
Sequence: MDTKTQIIDYDGNIMEDLKEWMIRNKLANLGFNYNVIAILGSQSSGKSTLLNNLFKTSFDVMNTKLGHSQTTQGLWLSFDTFEDSSAGPSEQGSTTRKVNPTLILDVEGNDSKERGDNRLTFEHRSALFSLALADCVIVNLWYHSLGNFTASNYGLLKTVMEVNLELFQQDENCPKTILLFTVRDWFEEFASIDIVKNKIVEEYLNKIWTEMKKPPEAEKVNISNYFIVEVVGLSHGIIKKEEFLKDVENLRQKWINQLRPLQYSRNIPSDGFAHYCNNIWNTIVKQSQLDIPSQKEMLATFRCQEIKNNVISNASKVIKEKLAASSSQHSSTSIDEFKPWAEKEVVEKSLDEYFVDASRYTESICLKTSEELLDSLFIQLQTIVDNNLNFTQRVLAAKFANELNTMYSVCASDKNVFLFSKESNLQVRKDGKGGSSPSAGDKKDTKDTRSSQDKCIRLWSSFLLNADKLEYNTLCKFFEDYQKCNIEVKKRNKTHEFNYKPSLSILSTAICKDLNRIRNAQLTVLLDRTRATIKSRFKNMESLLITTKNPEEYWNHTLKIVKALQESINSNLTKCFINLKGGGAGPGSITTAGIIPNGGLYNDEDNTFHEDNLVEAHNSLSDNQTGHENDHYVEENLLNFHKIDVIKNKGKYISTVGEEIDKQVKNKNAIAELNSYYLDEIMDVLKSKLDEISDNLSSIIIQRFESVFNYDDAEQPRQWREISMAELKKIFRESKNYAFLIIDILQKNVQVEIIDDYLPNNFIKDEIVEKGKNKAKRKIQEMCRDAQYIQETGAKMSLKNVPLFFWVILLILGWNELLFFTRFFFRLNIILPLFLAAAVILSTLVFNGNMEVLSIINKAVFFLAKNSFGVYRQLQAMGGKAAQGAAAD
What is the function of this protein?
Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.
What are the official names of this protein?
Protein SEY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LDH1_BACC1
Sequence: MKKGINRVVLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKGSYEDCKDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGEYFNIGPHNIHAYIIGEHGDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFINVRDAAYHIIERKGATYYGIGMSLLRVTKAILNDENSVLTVSAYLEGQYGQKDVYIGVPAVLNRGGVREILEVELSEDEELKFDHSVQVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA_SALTY
Sequence: MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRIGAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSIGDGDINALIDEYESSYTLTPATQIHGDKRQNVREAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALDLNDMRQFAEIHDIEIAVIDNDTHLPAFKDALRWNEVYYGFKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: SCO2_BOVIN
Sequence: MLLLARPPKAWHRLFQLQPLALLGTPGGKTQHVRYQLFSTPGPADTGRQGQPQGPGLRTRLLVTALVGAGLGGAWLALRAEKERGRQQQRTEALRQAAVGQGDFSLLDHRGRVRCKADFRGQWVLLYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPLFITVDPERDTVAAMARYVQDFHPRLLGLTGSAEQIAQVSRSYRVYYSAGPKDEDQDYIVDHSIAIYLLSPDGLFTDYYSRARSAEQITDSVRRHMAAFRSVLR
What is the function of this protein?
Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2).  Involved in transporting copper to the Cu(A) site on MT-CO2/COX2.  Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
What are the official names of this protein?
Protein SCO2 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ADH_DROSL
Sequence: MVIANSNIIFVAGLGGIGLDTSREIVKSGPKNLVVLDRIDNPAAIAELKALNPKVTITFYPYDVTVPLAETKKLLKTIFDKLKTVDLLINGAGILDDTQIERTIAVNFTGTVNTTTAIMDFWDKRNGGPGGVIANICSVTGFNSIYQVPVYSASKAAALSFTTSLAKLAHITGVTVYSINPGITKTVLVHKFNSWLNVEPRVAELLLEHPTQTTLQCAQNFVKAIEANQNGAIWKLDLGRLDAIEWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PSBT_PROM0
Sequence: MEAFAYVLILTLAVVTLFFAVAFRDPPKFDRK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: AROQ_GEOSL
Sequence: MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAIQAAAGTCDGILINPAAYTHTSVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAVGQITGFGADSYLLGLRALFTHIEKGIVTKG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: Y291_STRPM
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein M28_Spy0291.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RPE_MOUSE
Sequence: MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSLDR
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase, Ribulose-5-phosphate-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: RL25_YERPP
Sequence: MTTINVEVRNDQGKGASRRLRAANKFPAIVYGGSEAAISIALDHDTTKNLELKPGFYDSVLTLVIDGKETKVKVQAVQRHAFKPKLTHIDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: QUEC_POLAQ
Sequence: MSSLSAAYQNLAPRKDGAPAVILFSGGLDSTTVLALAKDLGYTPYALSVGYGQRHSSELAAAKHIAKQIGVARHEVVNLDLTRFGGSALTDSSIAVPTTPGKDQEIPVTYVPARNTILLSLALGWAESLGGLDVFYGANSVDYSGYPDCRPEYVASFETMANLATKAGVEAINNENRFRVHAPIISLTKAEIIQLGSTLGVDYSQTVSCYQANDLGEACGECESCRLRQIGFKQANVIDPTRYQKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: APKC_DROME
Sequence: MQKMPSQILNDGSSVSLNSASMNMANTPNSITVKTAYNGQIIITTINKNISYEELCYEIRNICRFPLDQPFTIKWVDEENDPCTISTKMELDEAIRLYEMNFDSQLVIHVFPNVPQAPGLSCDGEDRSIYRRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKHCTDQPEPLVKERAEESSDPIPVPLPPLPYEAMSGGAEACETHDHAHIVAPPPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMSLEDCV
What is the function of this protein?
Serine/threonine protein kinase which is required for apico-basal cell polarity in the germ line as well as in epithelial and neural precursor cells, for epithelial planar cell polarity and for cell proliferation.  During oocyte development, required for the posterior translocation of oocyte specification factors and for the posterior establishment of the microtubule organizing center within the presumptive oocyte.  Phosphorylates l(2)gl which restricts l(2)gl activity to the oocyte posterior and regulates posterior enrichment of par-1, leading to establishment of correct oocyte polarity.  Essential for apical localization of l(2)gl and par-6 in neuroblasts and for exclusion of mira from the apical cortex.  Phosphorylates baz which is required for targeting of baz to the postsynaptic region where it is involved in actin organization, and for apical exclusion of baz which is necessary for establishment of the apical/lateral border in epithelial cells.  Phosphorylates yrt which prevents its premature apical localization and is necessary for correct epithelial cell polarization.  Required for the establishment of mitotic spindle orientation during symmetric division of epithelial cells and for apical exclusion of raps/Pins.  Involved in symmetric adherens junction positioning during embryogenesis.  Required for polarization of the spermatid cyst which is necessary for sperm differentiation.  Required for stimulation of the Toll signaling pathway which activates Dif and dl and plays a role in innate immunity.  Plays a role in memory enhancement.
What are the official names of this protein?
Atypical protein kinase C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Apicolateral cell membrane; Peripheral membrane protein. Note=Cytoplasmic at interphase but localizes to the apical cell cortex during mitosis.