PharMolix/UniProtQA huggingface dataset:
Protein: FB293_ARATH
Sequence: MKRYQNLKVGEAFSKNRIYPFACNELSSILNLAYSLSPKNVKALIFQDTLSAFRLLPDINTSAAVSAANLLLKSVEAVLPKQKKNLAIVEFKQAKVALKRRSKNREEEDIDIPSLPQDILIHIFSFLEISSLVSSAQVSRSWNQATHENSLWQSQFDLHFNHKVLIRMQSDIDWREAFKKAYIAANSSEALRSGRGYCSYCDSIVWHENLRCLNKQCRLKSGNKPLDLITTHQVVNYLLGIESSDDESESDDEAFPGRLWKLSYVPDYL
What are the official names of this protein?
F-box protein At5g52880.
Protein: SYP_STRP3
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRNAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTKSSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_THEM4
Sequence: MRKYNDKHIPVLPNEVVEYLLWKDNGIYVDCTAGEGGHTFLIAKKCPNSRVIAIDVDLEVLEIAQKNLKAFHNVILLKASYVDLPVVLKSLGIERVSGILADLGISTYQLKAEGRGFSFNRDEPLDMRMDIQQDTSAHKITNFYSEEKLSKIIFKYGEERFARRIAKQIVKNRPINTTKELVEIIKKALPPSEIRKRKRHFATKTFQAIRIEVNKELKNIEQLLKNAEELLEIGGRLAIISFHSLEDRIVKHFIKNSNNLKHIAGPIKPTQEETKNNPRARSAKLRVAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_CAMJE
Sequence: MASYSMGDLKKGLKIEIDGIPFKIVEYQHVKPGKGPAFVRIKIKSFIDGKVLEKTFHAGDKCEAPNLEDKTMQYLYDDGENCQFMDTQTYEQVAISDDDVGEAKKWMLDGMMVDVLFHNGKAIGVEVPQVVELKIIETAPNFKGDTQGSNKKPATLETGAVVQIPFHVLEGEVIRVDTVRGEYIERANK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COWN_AZOC5
Sequence: MRASPTPWLSRAEPYCQRESPMNLLTTTPAGDRYVTFNGIDFEGNMARVLAHLRRYIDDPRTGNAFWDRFKARLAAAESGGNAFQDKLLLLHSHVYYMGDLFEDQEDEAALADLRKLEEECF
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: PHEA_LACLA
Sequence: MKIAYLGPRGSFCSVVAETAFVSEELFAYDSILDVIEAYDEGKCDFALVPIENSTEGTVNMSIDKIFHDSKATVVAEFVLPISQNLLALSKEGKIEHIYSHPQALAQTRNYLREHYPQAKVEITDSTSAAAEFVKNHPDLPIAAVANSYAAKMYDLEIVAKNIQDLAGNSTRFWLLGKEKKSFDLLKTGEKVSLALTLPDNLPGALHKAISVFAWRDIDMTKIESRPLRTRLGQYFFNIDLVNNEKNNLKIPYALEELSGLGVKVRLLGNYAVYSLGEG
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: SMRCD_BOVIN
Sequence: MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRAGTPDSDVTEKTEDSSVPETPENDRKASISYFKNQRGIQYIDLSSDSEDVVSPNCSSTVQEKKFNKDTVIIVSEPSEDEESQGLPTMATRNNNDITNLKNLSFFPNYSDNLSTVRQTRYSENLSSDLLKLIDSTSTMDGAIAAALLMFGDAEGGGPRKRKLSSSSEPFEEDEFNDDQSMKKKRLDHGEESNESAESSTNWEKQESIVLKLQKEFPNFDKEELREVLKEHEWMYTEALESLKVFAEDQDMQYASPSEFPNGKEVSSRSQNYPKNAAKTKLKQKCSMKPQNGFNKKRKKNVFNPKRVIEDSEYDSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRPFNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIKLMNKCEDISNKLTKQVTMLTGNGGGWNTEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNKGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRYNIHSRYEEYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYMNLFNRLKKSINNMEKNTEMCNVMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLIGQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL
What is the function of this protein?
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization.  Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.  Required for the restoration of heterochromatin organization after replication.  Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with PCNA at replication forks during S phase. Recruited to double-strand breaks (DSBs) sites of DNA damage (By similarity).
Protein: MPH1_NEUCR
Sequence: MDDDDFDDIPDEDLMLAFTQATGNITSHHPSNSKQLASSAKPPAQAWPISDSARRIVTPTVSQGQATATGRAKTASKPTTSATTSRPSLAQSSQRKNLRQTTLWGGTLEEDAQPAPQAVSNRPFRADMPPEQPTHHEIDIEEMKTWVYPMNLGPIRDYQFSIVKNGLFNNTLVALPTGLGKTFIAATIMLNYIRWTKTAKAVFVAPTKPLASQQVQACLSIAGIPRSQATLLTGETPPVLREDEWATKRLFFMTPQTLMNDLSKGYADPKSIVLLVIDEAHRATGDYAYVKVVEFLRRFSKSFRILALTATPGSSLEGVQDVIDNLGISHVEIRTEESIDIRQYVHSRDINTITFDPSDEMMEVRDLFSKALKPLVTKLSSQNIYYGRDPMSLTTYGLMKARNDWMAGPGRHVNQGTKFSVIATFAILQSLAHSIKLLNFHGIKPFYNNLAEFRTTEEEKGGKGSKLKRQVLEDENFQKMMDMIEGWMKIDGFLGHPKLEYLCETLVNHFMDAGEGSNTRAIVFSEYRDSAEEIVRILNKQPLIKATVFVGQADSKRSEGMKQKQQIETIEKFKNGAHNVLVATSIGEEGLDIGQVDLIVCYDASASPIRMLQRMGRTGRKRAGNIVLLLMKGKEEDKFNEAKDNYATMQRMICEGSRFTFRHDLSSRIVPRDIRPEVEKKVVEIPLENSQNPELPEPKRSAARMRTKPAKKKFNMPDGVETGFIKASFFGQAGAKTAKPPARPPAPKETDFIAERPKLESILLSTSQENELRRNYTKIPLGHSKVEELDIDWYRHPTSRRVVQKTIHVKHGEYTKRCVKLFRSLAKSQAPANRYTKPYGETDTSSWELIPLPPLADETEGETSRKGQKKRPRLESGQEAEEAEQYAAPKKRQATAKTKSTGVSKQTNKPRARHTALISDCEEGGNEYDGNVDDDEQSRPRNFRSKGRGRGSGRGKKSQPKQGDPNVDYGDDCTRTSDMEMGTDGSDDGADLEDFIVSDGEVTSSLQHRPRGSTSPTTAPDAGSSSLSSKTGRKQQAPDSFASDEDDGDVFGPKFVPVTASAAKGSLPSTARREKPKPFYVPVELPATQDTTDGDDDLPDIEFLSAKRKREGTGTGMRTGSPGHVKVGDTSKGGSGGDQTREKPSGGAASHARARKRTVVMDSDDDQE
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase mph1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_FUSNN
Sequence: MAEFRRRRAKLRVKAEEIDYKNVELLKRFVSDKGKINPSRLTGANAKLQRKIAKAVKRARNIALIPYTRTEK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: UBIX_DEIRA
Sequence: MSDAPSGPPRLVVGVSGGSGIPYALDILRALRGLDVETHLVVSSGAKRVMSAEGGPQLADLTALASVVHDDRDLAAAVASGSYRTGGMLIVPCSAGTLAKVAHGFADNLISRAAHVTLKERRPLVLVVREDPMPRPMLQNMLAAHDAGATVMSASPGFYHAPESLGELLGFVTARVLDQFGLNAPGFRRWREDEA
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: DHX30_MOUSE
Sequence: MVTPVCNSSTWQPKDSSFLSWPEMFSLDSFRKDRTQHRQRQCKLPPPRLPPMCVNPAPGGTITRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSSWISPELRLQSDDILPLGKDSGPLSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLRGPCGSFDMRKTADD
What is the function of this protein?
RNA-dependent helicase (PubMed:25219788).  Plays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity).  Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity).  Associates with mitochondrial DNA (By similarity).  Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (PubMed:25219788).
What are the official names of this protein?
ATP-dependent RNA helicase DHX30, DEAH box protein 30.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. Relocalizes to stress granules upon heat stress.
Protein: SKSP3_ASCTR
Sequence: ILCINVAGRRIC
What are the official names of this protein?
Skin secreted peptide 3.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_OSTTA
Sequence: MSPSIAMFTLTPNARALASKTSKMDLIKNLRERTGAPIVDVKAALTAHDYDSEAAYDALRAKGLAAAAKKAGRTSADGAVAALSGDRGVVLFEVNSETDFVARGESFQSLIKECAEATLRAVESDRAMTEEHGTATAGALRALRDERIGELLTSDGKPLSDAVRDVAVHVRENVRLRRAFAYAATVGAGEVIGTYVHGALAPGVGKQAACVVAKGVSEEFANKLAMHVVASSPLYLRSDCVPTDVMERELAVFRTQTEGSGKPANIVEKILAGRMNKYYEEVCLENQKFILDDSMTVEKAVKAEGGELVAFSRVKVGEGIEVEEKDFAAEVAEAVRTT
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNPH_SHEB2
Sequence: MRPSNRTPAQTRPITITRQFTAHAEGSVLVEFGETKVLCTASFTEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMDREAARGKQSGRTQEIQRLIGRALRACVDMKALGENTIVIDCDVIQADGGTRTASITGACVALVDALNWARGKGIIKSNPLKFLIAAVSVGIYKGEAISDLEYIEDSAAETDMNVVMTETGKIIEIQGTAEGEPFSHEELLELLALAKNSIREIVDVQKAALN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: NLGNY_HUMAN
Sequence: MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.
What are the official names of this protein?
Neuroligin-4, Y-linked, Neuroligin Y.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density membrane.
Protein: TRHO_STRPJ
Sequence: MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ALDA_STAHJ
Sequence: MAKVNVRDFIEEQYGLFINGEFQASESGDTLTVTNPANGEDLAKVAKASKSDVDKAVQAAQDAFDSWSKTSKEERADYLLEISRRIHEKVEHFATIESLQNGKPYRETSTIDVPLTANQFKYFASVLTTDEGSVNEIDENTMSLVVNEPVGVVGAVVAWNFPILLASWKLAPALAAGNTIVIQPSSSTPLSLIELAKIFQEVLPKGVVNVLTGKGSESGDAIFNHEGVNKLSFTGSTDVGYGVAKAGAERIVPTTLELGGKSANIIFDDANLDQVVEGAQLGILFNQGEVCSAGSRLLVQSSIYDKVMPKLKEAFENIKVGDPFDEDVKMSAQTGPEQLEKIESYVKIAEEDSNANILTGGHRLTDNGRDKGYFFEPTIIEIKDNSHQLAQEEIFGPVVVVEKFEDEAEAIKIANDSEYGLAGGIFTTNINRALNVAKAMRTGRIWINTYNQFPAGAPFGGYKKSGIGREIYKDAIKNYQQVKNIFIDTSNQTKGLY
What are the official names of this protein?
Putative aldehyde dehydrogenase AldA.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: MATK_VERAR
Sequence: MEKIQRYLQLERSQQHDFLYPLIFQEYIYAFADDRTFSRXXSILSGNPDSENLGSRKKYSLLIVKRLITRMYQQNHFLISSNDSNQNKNPFWGRNKDFYSQILAEGFAFIVEIPFSLQLLSSLGGKKKRVVNSQNLRSIHSIFPFLEDNFSHLHFVLDILIPHPVHVEILIQTLRYRVKDVSSLHLLRFLLNEYCNCNSIITTKKAGSSFSKRNQRLFLFLYNSHVCEYESVFGFLRNQSFHLRSASSGALLERIYFYGKVERLVNAFDKVKDYQVNLWLVKEPSMHYVRYQRKSILASKGTSHFMNKWKCYLITFWQWHFALWFHPRRISRNQLANYFLEFVGYLSNIRTNPTVVRSQSLQNXFLINNAIKKFETLVPIIPLISSLAKAKFCNVLGHPTSKPVWADLSDSNIIYRFVHICRNLSHYYSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRVFLKTLGSGLLEEFLISEEDVLCWTFPKTSSALRGVYKSRIWYLDIICINDLANLK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LIPB_AFIC5
Sequence: MVNARDTLISLPFSAASGPGVEWRITDSYVAYEDALAAMEARAAAIADGTAPELVWLLEHPPLYTSGTSAKASDLIEARFPVFPSGRGGQFTYHGPGQRVVYLMLDLKHRRPDVRAYVANLEELIITTLAAFNVRGERREDRVGVWVKRPDKGDGYEDKIAAIGVRLKRWVSMHGIAINVEPELSHFAGIVPCGIEDSRYGVTSLADLGLPVTMHDVDIALRQAFEQVFGEVHGVADQMAETTN
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LST8_BOVIN
Sequence: MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEITPDRTMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNVASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG
What is the function of this protein?
Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals.  mTORC1 is activated in response to growth factors or amino acids.  Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1.  Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases.  Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.  mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E).  mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.  Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity.  In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity.  mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive.  mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.  mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.  mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation.  mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'.  mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657' (By similarity).
What are the official names of this protein?
Target of rapamycin complex subunit LST8, TORC subunit LST8, G protein beta subunit-like, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OS9_ORYSJ
Sequence: MGLAGGARVVLFVVAAAAAAALTAAADQIFTSSGAPFGRNSREPRYHVEFHPVDAPFNPENGQESVPMTSHVGKHYTCFLPVEETKTMKSIIPQNATNVIIESERRVKPKDPDELLEILKDQCFYRHEGWWSYEFCYYGKIRQVHVEGEKVIQEYVLGEYDADATDAYYENQTSDSADEDDNLIDTSKRYHVHLYTNGTVCDLTDMPRETEVRFVCSEPTVVISSIKEISSCKYVLTVQSPMLCKNPLFQQEKRTLSIHCNELLAEAEATVDDDSLPKEAQIIIPDPDGLHNYAAYAT
What is the function of this protein?
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD).  May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation.
What are the official names of this protein?
Protein OS-9 homolog, OsOS9.
What is the protein family that this protein belongs to?
Belongs to the OS-9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: PURP_PYRFU
Sequence: MKVRIATYASHSALQILKGAKDEGFETIAFGSSKVKPLYTKYFPVADYFIEEKYPEEELLNLNAVVVPTGSFVAHLGIELVENMKVPYFGNKRVLRWESDRNLERKWLKKAGIRVPEVYEDPDDIEKPVIVKPHGAKGGKGYFLAKDPEDFWRKAEKFLGIKRKEDLKNIQIQEYVLGVPVYPHYFYSKVREELELMSIDRRYESNVDAIGRIPAKDQLEFDMDITYTVIGNIPIVLRESLLMDVIEAGERVVKAAEELMGGLWGPFCLEGVFTPDLEFVVFEISARIVAGTNIFVNGSPYTWLRYDRPVSTGRRIAMEIREAIENDMLEKVLT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NUOB2_SALTO
Sequence: MGIEEKLPAGVLLTSVEKFVNWSRKSSVWGATFGLACCAIEMMAAGGPHYDMGRWGMEVFRASPRQADLMIVAGRVSQKMAPVLRQIYDQMAEPRWVLSMGVCASSGGMFNNYAIVQGVDHVVPVDMYLPGCPPRPEMLIDAILKLREKIMHEPLGPNGRKMAEARKARGDVPVVPYGSMPSSYRSDKARRAEWTKAVREGREEQLRIENWMKAQPHLQQYEGLKK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.