PharMolix/UniProtQA huggingface dataset:
Protein: NSCD_ARTBC
Sequence: MTSVPIFESVSRFLPPANEDEKFWWKVTGRHMARMMHEAGYPEDRQVECLLFHRFKVVPCLGPRPHSDTPWYKSRVGGGAADGCPINYSWRFGTADRRPHIRNFIEPLGALTNTSADPLNEVATKALLHDYSMTLPNVDLEAFWTFAPHYRPRIIEKADMEKLAGASLLVGAEMSPDSHTIDIKAYMYPRVPSQTSQLLTTILPQAMRDAYGEDVCLDSLNFVHDFMTKDPQGCQLVLTGTTGIDCCKLQDTRVKIYVITRNTSFDHIAAIVTLGGRRPISEELLGQLKALWYELKGAPAELPSSEQLPVQTKPDGSKNPIVVPFYFDIQPRLALPDVKAYIDVSTSPVSDLAAANAVVCHLEQHGSGQNPRAYLNVLKDITPVEELETQKGALAFYSVAVKKNELDITSYFNPQVYKRYFAHEVQLNGQRRSVFE
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
Prenyltransferase nscD, Neosartoricin B biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: TPL_LACSW
Sequence: MDMMKFAPEPFKIKMVEPMGNLNKEERKDAIRTAGYNTFLLKSEECFIDLLTDSGTNAMSDRQWAGLMLGDEAYGGSRNFYHLEETVRELFGFKYVVPTHQGRGAENILSSLTIKPGDYVPGNMYFTTTRFHQEHNGATFRDVVIDEAHDPNAILDFKGNIDLNKFQALIDEVGAERIPYICLAVTVNLAGGQPVSMANVKAVSELAHKHGIKVMFDATRCVENAYFIKTREKGYEDKSIKEIVHELFSYGDGCTMSGKKDCLTNIGGFLCMNDKDLYIRATGMVVQYEGMPTYGGMAGRDMEAMAIGLRESMEYNYISHRVNQIRYLGEKLDAAGVPMVKPSGGHAIFVDARAFLDHLDQKTDFPAQALAAAVYEFSGVRTMERGIISAGRDIKTGEDHVPKLETIRLTIPRRVYTYAHLDYVADAIIQLYQMRRDISGLKWVYEPAVLRFFTGRFEPKNGELIKGF
What are the official names of this protein?
Tyrosine phenol-lyase, Beta-tyrosinase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: CYSH_BACAC
Sequence: MLTYETWEENETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLDLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNSLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_BACP2
Sequence: MNDLSTMSSLTKEEILQLIEEATALKKGKQELGLAGEFVANLFFEPSTRTRFSFEVAEKKLGMNVLSLDAASTSVQKGETLYDTVKTLESIGVKACVIRDSTDEYYNELIGKVGIPIINAGDGCGQHPTQSLLDLMTIYEEFGGFEGLTISIHGDIKHSRVARSNAEVLSRLGATVLFSGPASFQDEQNPHGTYVQVDEAIKQSDVVMLLRIQHERHTEKMGNEDYLSTYGLTVNRAKNMKERAIIMHPAPVNRGVEIDDSLVESKQSRIFKQMENGVYVRMAVLKRAFQNSKLHQKGRESVYVVSH
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: IHFB_PSEA8
Sequence: MTKSELIERIVTHQGQLSAKDVELAIKTMLEQMSQALATGDRIEIRGFGSFSLHYRAPRVGRNPKTGESVRLDGKFVPHFKPGKELRDRVNEPE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PROAR_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LTMD1_XENTR
Sequence: MLSGMALCRTRNCRFMMGEDGRRMRKCVLLLYQPCHLSTNSKPKSMLSLIASKAKYANEKYEHFLERKFPNFYLLYSTFMKGFRMLMTEAKEVGRIKQRMNHQGIPFHQLPYREMEKLRQFRRDIIKAAPVVIISIPPFANYLVFVLMYFFPRQLLIRHFWTPKQREEFLDIYHRMRVEAYPEILDGLLNAVPKLSERNLRNQMFQLCTQVQHGTHPQVENLHAVCTAFSGPPLGMKRLDVQQMKALSRVMFLTPHLPAFLLQHRLGSHICEIQNLDCALLKLGVNELSEEELKRACYIRGLNSTHLSREDCETWLHCWLQLSSMLKVSEASLLLHCMVLLSANYLQSIKQ
What is the function of this protein?
May play an essential role for mitochondrial structure and function.
What are the official names of this protein?
LETM1 domain-containing protein 1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: Y1705_STAAN
Sequence: MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGTFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
What are the official names of this protein?
UPF0421 protein SA1705.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_METSB
Sequence: MANLEKIVEDLSTLTVLEAAELAKLLEEKWGVSAAAAVAVAAGPAAGAAAAAPAEEQTEFTVVLAAFGDKKIEVIKEVRAVTGLGLKEAKDLVEAAPKPVKEGVTKEEAEKIKAALEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RR2_CHAVU
Sequence: MNHLYSKTNLEEMLEAGVHFGHQSHKWNPRMAPYIFSERKGVHIIDLIQTSNLLHEACDFLANAASNKKEFLLVGTKFQASDLIKSEALKSRCHYVNQRWLGGMLTNWMTIETRIQRLKNLETQEKLGAFHHLPKKDAAHLKRQLNQLQKYLGGMKYMKNLPDVVIIVDQQKEIIAVQECRVLGIPIIALVDTNCDPEIVDIPIPANDDARSSIRWILSKLTAAIRDNRF
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABZ_FRATO
Sequence: MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_ECO7I
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: FARS_CITJU
Sequence: MKDMSIPLLAAVSSSTEETVRPIADFHPTLWGNHFLKSAADVETIDAATQEQHAALKQEVRRMITTTANKLAQKLHMIDAVQRLGVAYHFEKEIEDELGKVSHDLDSDDLYVVSLRFRLFRQQGVKISCDVFDKFKDDEGKFKESLINDIRGMLSLYEAAYLAIRGEDILDEAIVFTTTHLKSVISISDHSHANSNLAEQIRHSLQIPLRKAAARLEARYFLDIYSRDDLHDETLLKFAKLDFNILQAAHQKEASIMTRWWNDLGFPKKVPYARDRIIETYIWMLLGVSYEPNLAFGRIFASKVVCMITTIDDTFDAYGTFEELTLFTEAVTRWDIGLIDTLPEYMKFIVKALLDIYREAEEELAKEGRSYGIPYAKQMMQELIILYFTEAKWLYKGYVPTFDEYKSVALRSIGLRTLAVASFVDLGDFIATKDNFECILKNAKSLKATETIGRLMDDIAGYKFEQKRGHNPSAVECYKNQHGVSEEEAVKELLLEVANSWKDINEELLNPTTVPLPMLQRLLYFARSGHFIYDDGHDRYTHSLMMKRQVALLLTEPLAI
What is the function of this protein?
Sesquiterpene cyclase catalyzing the production of beta-farnesene from farnesyl diphosphate.
What are the official names of this protein?
(E)-beta-farnesene synthase, CjFS, Terpene synthase 10.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BORA1
Sequence: MSVADIRNSAESRMSKSLDTLKVNLSKIRTGRAHAGILDHVQVEYYGSPVPVGQVANLNLVDARTISVQPYEKHMAGPIERAIRDSDLGLNPVSLGDTIRVPMPALTEERRRDLTKVVRSEGEDAKVAVRNLRREANEALKKLVKDKIISEDDERRGQDEVQKLTDRAVADIDKMVTQKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEBB_PROMA
Sequence: MIIKRDNSLSKIDLRDWIWTPFFNDLVDKLSVFEIEPYPVSHDFLSKESITGSRRNPVHVTTLTWAAKFEKIKQVRLACIKGGESLSVFNLLIHPLNDYDLPFFGADFVTLPNGHLLALDLQPALKLDNIHTENVWPRLIPLHDHWQSLLPSGGEIPKEAEPYFSPGFLWSRLPLSKESDNIISEILRPAFGEYLSLYIELLHIAKPLKKERALKILEGQKAYINYRSTKDPARAMLCRFYGKEWTEDYIHKVLFNI
What is the function of this protein?
Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin.
What are the official names of this protein?
Phycoerythrobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: RPOC_COLP3
Sequence: MKDLLKFLKQQNQTEDFDGIRIGLASPDLVRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESYVVTEPGMTTLEKSQILTEEEYLDALEEHGDEFDALMGAEAVLALLQQIDLDGEVAQMREELPEIGSETKRKKITKRLKLMEAFAASGNKPEWMIMNVLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLVAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKKMALELFKPFIYGKLEARGLATTIKAAKKLVEREGAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIHLHPLVCAAYNADFDGDQMAVHVPLTIEAQMEARTLMMSTNNVLAPANGEPIIVPSQDVVLGLYYLTRFRINGLGEGMYFTDEKEVEKAYRTGVAELHARIKVRITEHVKNADGEWEPVTKLRDTTVGRAIMWQVCPKGLPYDLIDKPLGKKPISKLINHAYRNLGLKETVMFADQIMYTGFHYAMIAGCSVGIDDMVIPEAKYTIVEDSEAEVAEIQAQFDQGLVTAGEKYNKVIDIWSSANEKVSKAMMDNLSKEMVMNRDGEMEEQDSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIKANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTNHDCGTHDGLLMTPLIEGGDVVEPLRERVLGRVVCDDVLIPGTDEVLLPRNTLIDEALCDVIEDNSVDQIKVRSIITCKTDFGICANCYGRDLARGHMINQGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRATAESSVQVKNTGTLKLQNAKFVTNSEKHLVITSRSSELTIIDEMGREKERYKVPYGSVLSKNDGEAVNSGDTIANWDPHTHPIITEVAGKVQFVDLADGVTMVRQTDELTGLSSIVITDAAQRNATGKEMRPALKLVDAKGKEVMIAGTEIPALYYLPGNAIVNLEDGADVGVGDALARIPQASSKTRDITGGLPRVADLFEARKPKLPAILAEKTGVVAFGKETKGKVRLLITQPSGEVYEEMIPKTRLLNIYEGEPVIKGEVIADGPESPHDILRLRGVAPVANYIVNEVQEVYRLQGVKINDKHIEVIVRQMIRKCEILDAGDSTFLKGEQVEVARVNISNRELEAEGKQPAEYEMQMMGITKASLATESFISAASFQETTRVLTEAAVAGKKDGLRGLKENVIVGRLIPAGTGYSYHQERARRKAAALAPAVESTVSADDAEKALTDALNSDLLSGNH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RSMH_VIBPR
Sequence: MTESFQHISVLLHESIEGLAIKPDGIYIDGTFGRGGHSRTILSQLGENGRLYSIDRDPQAIAEAKTIDDPRFTIVHGPFSGIAHYAKQHGLAGKVDGVLFDLGVSSPQLDDAERGFSFMKDGPLDMRMDPTSGIPVSQWLMEADLDDITWVIREFGEDKHARRIAKAIVAYRENEENEPLKRTSQLAKLISDAAPKSFKEKKHPATRAFQAFRIYINSELEEIDTALKGAAEILAPQGRLSVISFHSLEDRMVKRFIRKESQGPQVPHGIPMTEAQIQALGSANMKAIGKAIKPSKQEIELNPRSRSSVLRIAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_BRUSI
Sequence: MESGFKVTLKDAIRTIPDYPKPGVQFRDVTTLMGNAQAFRRAVDELVYPYAGNRIDKVAGIEARGFILGGAIAHQLSAGFVPIRKKGKLPRDTARIAYSLEYGVDEMEMHRDAIEKGERVVLVDDLIATGGTAEAAAKLLLQMGAEIVAACFIIDLPDLGGRKKLEALGLPVRTLVAFEGD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_GLOVI
Sequence: MTAVKTPIQVRYEVRNLELAAEGRQRIEWAAREMPVLKQLRQRFSQERPLAGIRISACCHVTTETANLAVALKAAGADALLIASNPLSTQDDVAASLVVDHGIPVFALKGEDTATYLRHVRVALDHRPQIIIDDGSDVVATMIKDRPDLIAGVIGTTEETTTGIVRLKAMLAAGVLTFPAMAVNDAETKHFFDNRYGTGQSTLDGIIRATNILLAGKTIVVAGYGWCGKGVALRARGMGANVVVTEINPVRAIEAAMDGLQVMPMAEAACLGDLFITVTGNKHVIRREHFAMMKDGAIVCNSGHFDIEIDLVALGELSSERRMVRPFTEEYTLEGGKSVIVLGEGRLINLAAAEGHPASVMDMSFANQALAVEYLIKNQGKLSPGIYNIPEELDRQIAALKLAAMGIAIDTLTPDQLHYISSWDEGTE
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_SYNJA
Sequence: MSRRKREDPWRYEAAIAEVESLIAQIESGELDLAEVVERFQQAAQTLKRCAEFLEEKRQQVEILIEELNQDDEDWQAF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_ALBFT
Sequence: MKTTELRQKDVAGLQAEVKELQKAHFGLRMQKATQQLNNTATLRSTRRDIARAKTILVEKQSAETSAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS8_SALPK
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NU2C1_NANDO
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSIAALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLFF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIM_METHJ
Sequence: MQTYPEILDFFMTLFGSILTDIREKTPLVHHMTNYVTVNDCANITLCIGASPVMAHAEEEVGEMVALAGALVLNIGTLDTLQIDRMFIAAKAAEKYGIPIILDPVGAGATSLRTKTAQRMIQELSISVLKGNAGEIGTLAGKQAQVRGVDSGGVNGDPTEITCGLAERLSCTVVMSGPIDIISDGSRTLLCENGHPYMGRISGTGCMAASVIGSCAAVTQDYLSASATGVSAFGIAGERAAVDAAGPGSFKCRLFDSMASVRSDDVDRYGRIRSV
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CM91_CONIM
Sequence: MSKVGVVPLIFLVLLSIAALQNGDDPRRQRDEKQSPQGDILRSTLTKYSYNIQRRCWAGGSPCHLCSSSQVCIAPTGHPAIMCGRCVPILT
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im9.1, Conopeptide im015.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_PSYA2
Sequence: MASFSTNEFKAGLKVMLDGNPCAILENEFVKPGKGQAFNRVKLRNLRSGKVLEQTFKSGDSLEAADVMDTEMNYLYNDGEFWHFMHPESFEQIQADKTAMSDSTKWLKENSNALCTITLFNGAPLSVTPPNFVELQITETDPGVRGDTSGGGGKPATLETGAVVRVPLFVQQGEVVRVDTRTGDYQTRVN
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_MICTS
Sequence: MADPRRDPAAESKDRPSTERVAAYTADAVRAAEAPLLAEGRPLMRTAARALADIAAAEVRTTPGAVLVLAGAGDNGGDALFAAADLASSAERVDVVLVRDRVHREALDAAVAAGARVVSVSDASAGVADYALVLDGILGIGRLADRRLRGSARALVERLLALAHRPRVLAVDVPSGLDPDDGTADAVILPADVTVTFGALKAGLVRGRGPELSGRVHLVDLGLEPYLRRAHPAVTAAIDVVRETPRAAETDRAQRA
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: PYRI_YERPB
Sequence: MMTQDYKLQVEAIKCGTVIDHIPAQIGFKLLSLFKLTATDQRITIGLNLPSKRSGRKDLIKIENTFLTEQQANQLAMYAPDATVNRIDNYEVVKKLTLSLPERIDAVLTCPNSNCISHNEPVDSSFTVKAQRGEISLKCKYCEKEFDHLAVLHAD
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: HRCA_FUSNN
Sequence: MSANKKVRGEIMGISEREKLVLNAIVDYYLTVGDTIGSRTLVKKYGIELSSATIRNVMADLEDMGFIEKTHTSSGRIPTDMGYKYYLTELLKVEKITQEEIENISNVYNRRVDELENILKKTSTLLSKLTNYAGIAVEPKPDNKKVSRVELVYIDEYLVMAIIVMDDRRVKTKNIHLAYPISKEEVEKKVDELNAKIRNNEIAINDIEKFFTESTDIVYEYDDEDELSKYFINNLPSMLKNENIAEVTDVIEFFNERKDIRELFEKLIEQKAQENSKSNVNVILGDELGIKELEDFSFVYSIYDIGGAQGIIGVMGPKRMAYSKTMGLINHVSREVNKLINSMEKDKNKKV
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: T2D1_STRR6
Sequence: MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDGQVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL
What is the function of this protein?
An M and P subtype restriction enzyme that recognizes the double-stranded and methylated sequence 5'-G(Me)ATC-3' and cleaves after A-2.
What are the official names of this protein?
Type II Methyl-directed restriction enzyme DpnI, R.DpnI, Endonuclease DpnI, Type-2 restriction enzyme DpnI.
What is the protein family that this protein belongs to?
Belongs to the DpnI type II restriction endonuclease family.
Protein: PX11B_HUMAN
Sequence: MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSADALESAKRAVHLSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFSLIMNLSRDAYEIRLLMEQESSACSRRLKGSGGGVPGGSETGGLGGPGTPGGGLPQLALKLRLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTLIYPWLRLKP
What is the function of this protein?
Involved in peroxisomal proliferation (PubMed:9792670).  May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane (PubMed:12618434).  Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455).
What are the official names of this protein?
Peroxisomal membrane protein 11B, Peroxin-11B, Peroxisomal biogenesis factor 11B, Protein PEX11 homolog beta, PEX11-beta.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.