PharMolix/UniProtQA huggingface dataset:
Protein: OOG1_MOUSE
Sequence: MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL
What is the function of this protein?
May down-regulate the expression of spermatogenesis-associated genes in female germ cells allowing their normal differentiation into oocytes (PubMed:29731491).  May act as a Ras-mediated signaling protein in early embryogenesis.
What are the official names of this protein?
Oogenesin-1.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=In early one-cell embryos, exists only in the cytoplasm and gradually moves to the nucleus at the middle one-cell stage. At the late one-cell and early two-cell stages, higher levels in nucleus than cytoplasm. After the middle two-cell stage, mainly cytoplasmic and completely cytoplasmic after the four-cell stage.
Protein: TPIS_STRS2
Sequence: MSRKPIIAGNWKMNKNPQEAQAFVEAIAGKLPAGDKIEAAIAAPAVDLNALLWFAKDSELKVAAQNCYFEDAGAFTGETSPKVLAEMGVNYVVIGHSERRDYFHETDEDINKKAHAIFRNGLTPIICCGESLETYEAGKAVEFVGAQVSAALKDLTADQVASLVIAYEPIWAIGTGKSATKDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVNPSNVAEYMACPDVDGALVGGASLEAESFLALLNF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPC3_MOUSE
Sequence: MSEDSEEEDYSDRSISDDDDLDEDSFMKFVSDDIHPCTLLAADSIGDPFFPRTTQILLEYQLGRWVPRLRGPRDLYGVSSSGPLSPTRWPYHCEVIDEKVQHIEWTPFVPEPVYVPTGLEIEPVYPNSKEDTVVYLAEDDHLCKAYKEPCFVYSRVGGNRTSLKQPVDNCDNTLVFEARFESGNLQKVVKVADHEYELTVRPDLFTNKHTQWYYFQVTNTQAEIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKYYKNNLGQDGRHFFSLTWTFQFPHSQDTCYFAHCYPYTYSNLQEYLSGINSDPVRSKFCKIRVLCHTLARNMVYVLTITTPLKTSDSKRKAVILTARVHPGETNSSWIMKGFLDYILGDSSDARLLRDTFIFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLLKESFPSVWYTRNMINRLMEKREVILYCDLHGHSRKQNIFMYGCDGSSRSKTKGLYLQQRIFPLMLSKNCPNIFSFSACKFNVQKSKEGTGRVVMWKMGIRNSFTLEATFCGSTLGNKRGTHFGTKDLESMGYHFCDSLLDYCDPDRSKYYQCLKELEEMEKHLSSERVSDNTDTSLVEISLDVESSSRGSDSSESNDTQTYLLKVTSQARNKKKYLKTKRERNAILANCQNNMQEVYGKEHLLQRHDESNSDGNDPRIDAPDVYVAHCFRRPLPNQGVVKIPGQRFYPGKTWSSSQRMIKSLNKDHRTCILETCKNPIQEVQSRGINIHESCFKMAKCPMNKRPSHWIEKTRIPTESHHQLKSKAKRCSSFQSKRTGTNWTDDEKRIYRDKRIAQTQEILKYLLPIVESSQNRKSTQMNNLINPIANLQQHQLIPTACINRRRYSIPWTPTRNLPFKAQRNLMTDTSEWLQSVPLGSFESLLPLCNLQKKTKHFELWGKKAKDVQLATSQWEAVPLSSNMDASIIRGNSVLQPKEFTMRSSKQRIPYLTKTSKKPSESDGLLTFQLKIHRNS
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins (PubMed:25103237).  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein (PubMed:25103237).  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:25103237).  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK (PubMed:25103237).  May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins (PubMed:25103237).  Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins (PubMed:25103237).
What are the official names of this protein?
Cytosolic carboxypeptidase 3, ATP/GTP-binding protein-like 3, Protein deglutamylase CCP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS7_CHLPB
Sequence: MAKKVVGGGVKPDLRFSDESVARLINAVMLDGKKDVAAKIVYGAMDIIAGKMKDEEPLEVFRRALSNVAPLVEVRSKRVGGATYQIPMEVKASRRDALAFRWIKLYATRRGGRSMSEKLAAELMDAASEQGASVKKRDEVHRMADANKAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ACPS_CHLPM
Sequence: MEIGVDIVELERIERAHNRYGRKFLEKFMTQPEIELCLAKPSPVASIAGRFAAKEAVVKALGTGISGGVFWKSFEVLNDSRGRPVVTLLDKACFPPGCVIKISISHDRHSAIAAALLQYKTRGRC
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR3_MACMU
Sequence: MTTSLDTVETFGPTSYDDDMGLLCEKADVGALIAQFVPPLYSLVFMVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLFTLPFWIHYVRERNWVFSHGMCKVLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYGTEKLFPKTLCSAIYPQDTVYSWRHFHTLKMTILCLALPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILISTYQSVLFGLDCERSKHLDLFVLATEVIAYSHCCVNPVIYAFVGERFRKYLRHFFHRHVLMHLGKYIPFLPSEKLERTSSVSPSTAEPELSIVF
What is the function of this protein?
Receptor for C-C type chemokine.  Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15.  Subsequently transduces a signal by increasing the intracellular calcium ions level.  In addition acts as a possible functional receptor for NARS1.
What are the official names of this protein?
C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDSB_COXB2
Sequence: MEFRVIIPARFDSTRLPGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGTERIAEAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLAEDLDEHDNVKVASLCTPITEVDELFNPHSTKVVLNRRNYALYFSHAPIPWGRDTFSDKENLQLNGSHYRHVGIYAYRVGFLEEYLSWDACPAEKMEALEQLRILWHGGRIHMVVAKSKCPPGVDTEEDLERVRAYF
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ARCFU
Sequence: MVQVVEVLVPGGQASPGPPLGPAIGPLGLNVKQVVDKINEATKDYEGLSVPVKIIVKDDRSFEIEVGIPPVSALIKRELGIEKGASNPGREVVGNLTMEQLLNIARIKRQQSLSYTLKEVVKEVLGTCNSMGITVEGKSPKELTRMIEEGQVEIPEE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SYA_ARTS2
Sequence: MKSQEITKRWIDFFVSKGHTAVPSASLVSSDPSLLFTVAGMVPFIPYLTAREEAPYNRATSVQKCIRTGDIEEVGKTARHGTFFQMCGNFSFGDYFKEDAIKFAWELLTTSVDDGGYGLPPEKLWVTVYEEDDEAEQLWLKNTGMPAERIQRMGKADNYWSTGQPGPAGPCSEIYYDRGPSYGVEGGPIADENRYVEIWNLVFMQYQIDNVRSKVDFDITGELPKKNIDTGLGMERLAMILQDVENMYETDQVRPVIDKAAALSGKEYTSAESADDPHHTDDVRMRVVADHIRSALMLIADGVTPSNEGRGYVLRRLIRRAVRSMRLLGVEKACLPDLLPASRDAMKGVYPVVETDFDRISRIAYAEEKAFLRTIASGTARLEDAVKDSKAAGQPLSGADAFALHDTYGFPIDLTLEMAEEAGLKVDEPEFRKLMLEQRQRAQADAKGKKGSHADLSAFQELLAEGETVFTGYTELAGESKVRGILSGGRKVSQASTGEEIELVLAETPFYAEAGGQAADTGLITGDGFVVEVLDVQRPVKGLSVHKAIVREGEIGADSLVQAAVDRERRHSAEQAHTGTHIVHAALHQILGPEALQRGSYNKAGYLRFDFAWGEGLSAATRSEIEEVSNLAIRNNFQVETKVMALAEAKALGAMALFGENYGNEVRVVEIDGAWSRELCGGTHVANTSLIGSLSLLGDQSVGSGNRRVEAFVGMEAFRHLAAERALVTELTEMLKVPSGLLADRIATTLTKLKTVEKELERLRKEQLTAAAAQLVGTAKDAAGVKVIAHDAGQVSGADDLRGLALDLRTRLGSEAAAVAVAGVSNDRPVILVATNEAARAAGVKAGALVRLAAGILGGGGGGKDDVAQGGGTDAAKVPAALTAVVDAITRR
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED24_DICDI
Sequence: MISMMETSTTEKKSNTDNSILKKIIIDSWRQRLSPIEWSLKLYNGFYNNNNNNNSNNNNNNNNNNNNNNVDNNEINSIELCEILLDLMNIGQSPSPLLVSYLRYAISIKLIGYNEFFESVYKFSSISRAQHFSVILDILFDVINIINYPSHHQNIFNSDNIENSNNNNNNNNNNNNNNSNNNIGFKVSSLSSSLKRNNSKIISTPIVTLLSSPSPSSSSSSSTSPSSQQPQPPQPQPLSYTSPIKKTVLIKNPDSTDSDEIMKVKEEPIKFKTTTTTTSTTTTTSTTSTTTNEISSSPPTNGNGEETTITTKTEDSNGINGIDSEDHKGENGKASPQMNGVHPGSDGNISHKRKEMDSNTIFDDDDSNGVDQHCSNKKMKHTDTLTQPQPKQIQNPQQQEQQQQQQENIEQNQHGNLHLHQPSQQQQQQQQQTSQPSLTTTTASAVTQTTTTASTINKSTKATTKKNYHKQLLSFTRLATLLFKVIEYYFQEDERINNINKSVNNNNNNNNNNNNNNNNNNNNNYNNNNNDSMDQNSNNPAVKYNSNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNILYKNSVKSLEILSIIQNNSTFKTLIYLAKYEFTLSSFKDLVLPFLAIQNSIRDNIVKQNIPSTQLISSQVKGQEFASQQTQLLNPLFQLIKQKYQKLFIDFRRILINKQEILPNHDIGSLVHGSSQSDKQIILSFEIIIDQEINGNHFKSSHTKLAISRGKPNELDTILNLKNNKNNNNNNNNSNGNGNGIDIGSSTDGSNKLSSTNIEEGNNNNNSSTHLNGNDQSQQSLDDEEPKQSQQQQLPPPSPPQQSHQKIQIQKQLQLIRQAKNLENVSDCFFKLLTLKTVKGLSDVEFLLEIVKILFQKLVRCNPNSNEYKKTRLFLLFKIPHFYSLMIDNYGNNNNNNNTNTNNINNNKNKNSKKSNNKNKNNKNNNKKNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGESSDKNEINPEGSIGSNNNNDNDNNDETNTNTSSNNNNNNNNSNDNENVTDNNKNNNSNTKNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKKNKDLNLHGNIIENVLYQINQFPSLYNVEDNIILSLIQILIKKHLVDINLLKSLFPNYHTDIDSIDSEIQSPPSSELSFDNLFDIHSIADIVKIKELIESLLNNSDPNNVSIMKRLFDFIKNHLINSFDYQDKLLNVLFNAKNIDYDSNKLLIAVIMYIFSDPLVIDTIDVHGYTLRLVMILIDVCESYGSSTTATTTEDIDIFKNENDNHDQKHLYFYFTIPFNLLYTLLIILYDVKNNKYNLDLIKSKLSESLNNKNNSRKSKSNNSSNNSINNINNNNNNNNNNNNNNNNNNNNNNNNNNFIQWIYNMIKDTNFSNGNGVNNVSTSFEFQFLKNLFDSDLGEDSIEKFQNFSQREYSSWDIVSKLPNVLYNIFDCYDRNIIQEEKVTQTMQLLFQYIPFSPIIVFDYLSKTKSSFFNVSPSSSTTTTTTTTSTTTTITTTTTNSSAYSTTTTTSASTSLPKSTDGKLLNGKSSNTSTTTTKNNGDTPTITTVITTMSSKNDKPLSLVEACLTNLNENRLLFRLSDYYKSLISEDHLNDLYKLFDPISETINLLLLSPKLQKFNELGYYSNQSTLFNSICLTNLSPPNQLSNMTPANAIRQVIDQFLTKSVSPNLSNLERDIKYIHMRLSNDLCQIVNLVSLEILDIILQSCQIESLYSIRAMELGGYILGGLIGIESLPILLNSIIPSWSEHIQTSLHGQLLSYFCFSSIVNSNALYYIQTDLCIQQSFKKFFLLLNDTMKRILSVAPLNGLITFCLSTITLFIHLNHSSITTYLYNSSSNTQLINQLYEIISKNQSLKKKQKLKQKKQQHNNNNGGEYNIDQDHIEQIQQQQQQYQKQQQQRKDEPNYEKLEEFIKTQYQRNNHSKLKSIFNILSISQLEDLSMSILNLSNFFLAISIFEDKNDLQYCSKLFN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 24, Putative mediator complex subunit 24, Putative mediator complex subunit 5, Putative mediator of RNA polymerase II transcription subunit 5.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPA_ECO24
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK3_PERSR
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, PerSu-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_RHIE6
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMKPYIFGDRNNIHIIDLAQTVPMLSRALQVVSDTVARGGRVLFVGTKRQASEIIADSAKRSAQYYVNSRWLGGMMTNWKTISNSIQRLRKLDEILGGEAQGFTKKERLNLEREREKLDKALGGIRDMGGTPDLMFIIDTNKEKIAIDEAKRLGIPVVAIIDSNCDPDLIDYPIPGNDDASRAIALYCELISRAAIDGIARQQSSSGRDLGASSEVPVEPALEEAAEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: UFL1_CHICK
Sequence: MAADWEEIRRLAADFQRAQFAEAAHRLSERNCIEIVTKLIAEKQLEVVHTLDGKEYVTPAQISKEIWDELSVCGGRINIVDLQQIINVDLLHIENRANDIVKSDKAVQLVLGQLINESYLDQLAEEINDKLQETGQVTISELCKAYDLPGDFLTQALSKRLGRIIHGRLDQENRGVIFTEAFVSRHRARIRGLFSAITRPTPVSNLITRYGFQEHLLYSVLEELVNTSRLKGTVVGGKQDKAVFVPDIYARTQSNWVDSFFKQNGYLEFDALYRLGIPDPAGYIKKRYKSTKLLFLRAACVGQEIVDRVEASVDEVISSGSWIDVATLLPSSLSVEDIGILLQQVMRSLNKNSSGLVFSDTIVVSEKFISSCTDLFSDMMKQKAEKEMKNSPVHLITEEDLKQSYVLENSYTNKKDKKDERRKKATEGSGSVRGGGGGNAREIKIKKTKKKGRKDADSDEESQATGTGRNKQLEFHFMSQEEMQDVLKTHLQDCPEELITELAEHLMRPLTKSYQEVVRSVFTSSTSSSGASGRQTMKDLQEEFSNLYNNIRLFEKGTKYFTDETQTNLAKHLLKTVCTDITNLIFNFLASDSMMTTENYSTITSEVRTKILGKLPEDTRGPLTKLHTSLNGKSLEDFLSYLDAAADICDIMVKKGDKKKERQVLFQHRQALIEQLKVTEDPALVLHLTAVLLFQFSTHCMLHAPGRSVPQIINFLSGKIPEDQHSLLIKYQGLVVKQLISQSKKAEQEDDNKTEEEEGADTIRKELQEITTSVKDLVLRPRKSSVTEE
What is the function of this protein?
E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to lysine residues on target proteins, and which plays a key role in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.  In response to endoplasmic reticulum stress, recruited to the endoplasmic reticulum membrane, and mediates ufmylation of proteins, thereby promoting reticulophagy of endoplasmic reticulum sheets.  Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR).  Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis, blood vessel morphogenesis or inflammatory response.  Also involved in the response to DNA damage: recruited to double-strand break sites following DNA damage and mediates monoufmylation of histone H4 (By similarity).  Required for hematopoietic stem cell function and hematopoiesis (By similarity).
What are the official names of this protein?
E3 UFM1-protein ligase 1, E3 UFM1-protein transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Cytoplasm, cytosol. Nucleus. Chromosome. Note=Recruited to double- strand breaks following DNA damage.
Protein: SDHA_HUMAN
Sequence: MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
What is the function of this protein?
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757).  Can act as a tumor suppressor (PubMed:20484225).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYH_FRATH
Sequence: MSKLTIVRGFNDVLPLDSYKWQFLESKVKLILDRYNYSETRLPIVERSELFHRSVGESSDIVSKETYDFQDRNGDSLTLRPEGTAGCVRMVIENNLATRGQTQKLWYCGPMFRYERPQKGRYRQFYQLGVEAYGFDGIAIDLEVIAIAWSLFKELGISEYVTLELNSLGSSLNRQEYTQALLQYLKPYHAELDEDSIKRLDKNPLRILDSKIEKTQKILANAPKLIDFIDHDLRLRFKQTCQYLDALGVRYKLNENLVRGLDYYTGLVFEWTTDKLGSQSAICAGGRYDGLVDNLGGQKTAAIGFAIGMERLLLLLEDLGKLPNQDNACDVFFILDSAQLHQSLAIVENIRQELPQLKIDMDLKFGSFKSQFKKADKSGAKVAIIIGQDELDNGFAGIKFLQQNEEQQQVAFNELINFLER
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_SALAR
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_CLOD6
Sequence: MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGGATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BDEBA
Sequence: MGPMCLNRHMGILLKNISTLLTLQGAAAKQGRRIKEEDLSLLQQAAVVIEKNKIVWVGPQKKLPKEFARKKALRDYDMRGRTVLPGFVECHTHLIFAGDRAAEFEMRNQGVSYQEIAAKGGGILSTMKKTRASSLNDLVKAGQRRLDHFVSQGVTTVEIKSGYALNLKDELKMLQAAQKLSGIRTVNTFLGAHALPPEFKSYEDYLTFLADEVLPVVAKKKLARRVDVFIEKGFFPPEASEKYLRRAQELGFEILIHADQMSLSGGSEIAVRLGALSGDHLLQIEDKEIRKLAQSEVTGVLLPTADLYTKTKYPPARAMIDAGVRVALATDFNPGTSPTQNLNLVGLLARLEMKMSLPEVIAAYTVGGAHALNLQNEVGSLEVGKSADILCIDQDWQTLFYSVGEASEKVVFSRGKKVFGTLK
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_RUTMC
Sequence: MNINLTMFGQLIMFTMFTWFCMKFVWPPIVMTMEERKKRIESGLLAAERGRSEQEEMQAKAQEMINQSKDQAAEIIANATRQASNMVEDAKDVALKEAGKVKAQAQAQLEQDTIQTRNELKNQMSDLIMQGVSVVLAKEVDVKVHQKMLGKLSQSLS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLU_PSEA7
Sequence: MSMTPREIVHELNRHIIGQDDAKRAVAIALRNRWRRMQLPAELRAEVTPKNILMIGPTGVGKTEIARRLARLANAPFIKVEATKFTEVGYVGRDVESIIRDLADAAVKMLREQEIQKVKYRAEDAAEERILDALLPAARPAMGFGDEPAREDSNTRQLFRKRLREGQLDDKEIDIEVADNPAGVEIMAPPGMEEMTNQLQNLFSGMSKGKKKTRKLKVADALKMIRDEEAARLVNEEELKARALEAVEQHGIVFIDEIDKIAKRANAGGADVSREGVQRDLLPLIEGCTVNTKLGMVKTDHILFIASGAFHLSKPSDLVPELQGRLPIRVELKALSPNDFERILTEPHASLTEQYRELLKTEGLGIEFAEDGIKRLAEIAWQVNEKTENIGARRLHTLLERLLEEVSFSAADLASEHSDKPIRIDAGYVNSHLGELAEDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HENMT_XENTR
Sequence: MELEFFKPPLYQQRYQFVKSYVDTYKPKKVADLGCSTCSLLHTLRFWDCIKVLVGLDIDEDVLSRKKFTLTPLPAHYLEPRNTSLTINLYQGSVTQKDPALLGFDLITCIELIEHLEAEELENFREVLFGFMAPITVIISTPNAEFNILFPKCTGFRHPDHKFEWNRREFQSWATEVAKCFNYTVEITGVGEPPRDSKNVGFCSQIAVFTRNYTESEESLQRKMECKSVYKTVLHIVYPSLQEEKYLRRAVQKVALFHAYQIKANFLQQFIHREEEEEPHNTDTEHRPCMDLKLTSRWPTLPQTEQDESMEPFLQEDTLYVPLKKIFSVPKVKELCGNMDNLRTMITGEATLSNDGNAILYHIDLENSC
What is the function of this protein?
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.  This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation.  Stabilization of piRNAs is essential for gametogenesis.
What are the official names of this protein?
Small RNA 2'-O-methyltransferase, HEN1 methyltransferase homolog 1, piRNA methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. HEN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.