PharMolix/UniProtQA huggingface dataset:
Protein: RS10_SYNSC
Sequence: MSTAIAQQKIRIRLKAFDRRMLDLSCEKIIETADNTAATAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DIR11_ARATH
Sequence: MLQITNMATPFLLLLLPLIFSTVLLLTITVTQSKPYSKTTPFQGNKPDKLTHLHFYFHDIISGDKPTTIRVAEAPGTNSSATVFGAVLIVDAPVTEGPELSSKEVGRAQGLYASTDMKTFGFTMVFNFVFTEGEFNGSTAALYGRNPILLEERELPIIGGTGDFRFARGYALPKTYKVVNIDAVVEYNVFIWH
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 11, AtDIR11.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PROX1_MOUSE
Sequence: MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDVDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQVYDSTDSENDEDGDLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGSNKERDHGPNSLQPEGKHLAETLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGSVQMPSSTDQTEALPLVVRKNSSEQSASGPATGGHHQPLHQSPLSATAGFTTPSFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECGDLQDMSDISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE
What is the function of this protein?
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs.  Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system.  Involved in the regulation of the circadian rhythm.  Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
What are the official names of this protein?
Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1.
What is the protein family that this protein belongs to?
Belongs to the Prospero homeodomain family.
What are the subcellular locations of this protein?
Nucleus. Note=RORG promotes its nuclear localization.
Protein: NRP_PINMA
Sequence: MSRLTLLVLLVIAAVIQKVHGQGRENEKKNEHEPGNQDGGNQNEKTERNLREPNRQTRRFNTRNDNRNRNIMQKRAMLLWQRRMNQRSNQNNFGNNRSIPPTNTFNRNRSRTKSNKSEVEKENGSNKASKGKMQSGDGGGNGSEKEGPERRKVQHRIAKRFQKRHPSNSPKPKPARKTTNQQYRRHFMNNYNNKYWNWRRNMLNRRRTSPQHYQNQQARWRYYRYGPYTWYRYKNKWRLVRYNNMYRRNIKTNQSKKSNQNNQGD
What are the official names of this protein?
Asparagine-rich protein, Nacre uncharacterized shell protein 5, NUSP5.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_RICCN
Sequence: MILVNVHAGNCDNTLKNFKKKLQRELYFRKMKEQRYYETPSAKRVRKVQEAARRQRKFARKKMFDE
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PBN1_SCHPO
Sequence: MDLQRTNQDTGTTTLFKVVISNTVNYLPKGVWILRNNTIDSLSIAKQFREIKNNINISHLSRENYWVETPFGKVFHSEVVSEEFMQIFIDKGNKALNNEEMIFACMSEKGWNVSLETVPNLDIPVGSYETQLGLPVGLHPKLHVHLKNLHKPEDECSLQGFMYIPPTLFIDRYELSNIAEMHADNLGHVLGIWGETDLEAPSYKLNGTGSFFWFDIYTDDGLLQKDYIDTIIPLHTRYQSPLKGQTYLKTSLTNPKFFWNCDTEDKVNDFRFLFSSKNKYTLQNDPTTLSISIPIADLSYKHVVEWVTNGVAIFSFFYLLLYLWKRFRYAKD
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
What are the official names of this protein?
Protein pbn1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: PTAFR_PIG
Sequence: MEPNDSWRVDSEFRYTLFPIFYSIIFVLGVIANSYVLWVFARVYPSKKLNEIKIFMLNLTMADLLFLVTLPLWIIYYYHEGNWILPKFLCNLAGCFFFINTYCSVSFLAVITYNRFQAVTRPIKTAQATTRKRGISLSLIIWVAMVAAASYFFVLDSTNIELSKTGAGNLTRCFEHYEKGSMPVLIIHIFLVFSFFLVFLVILFCNLVIIRTLLTQSVQMQRNAEVKRRALWMVCTVLAVFIICFVPHHIVQLPWTLAELGFQSGNFHQAINDAHQITLCLLSTNCVLDPIIYCFLTKKFRKHLSEKFYSLRGSRKCSRVTTETGTEVVVPLSQVPVNSLKK
What is the function of this protein?
Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity.  Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.  May have a role in peri-implantation development during pregnancy (By similarity).
What are the official names of this protein?
Platelet-activating factor receptor, PAF-R, PAFr.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_ECOL6
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ECTB_STRAW
Sequence: MTITQPDLSVFETVESEVRSYCRGWPTVFDRAQGSRMYDEDGHAYLDFFAGAGSLNYGHNNPVLKRALIDYLERDGVTHGLDMSTAAKRAFLESFQNLILRPRDLPYKVMFPGPTGTNAVESALKLARKVKGREAIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGKVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARPEWLRALAELCKRQDMLLIVDDIQMGCGRTGAFFSFEEAGVTPDIVTVSKSISGYGLPMSLCLFKPELDIWEPGEHNGTFRGNNPAFVTAAAALQTYWADGSAMEKQTLARGEQVEQALISITEENLADVKEYRGRGLVWGIEFKDKDRAGRIAQRAFELGLLIETSGPESEVVKLLPALTITPEELDEGLRTLARAVRETA
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: MRAY_CLOP1
Sequence: MEILKSMIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFIFATIITMFIMVGNPTDEAMIALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIVSGFLTWYAYKYIGTSINIPFLNGQINFGLFYIPFVMFYFAGVTNAVNLTDGLDGLATSVTVLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMVALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVSVFSIITVVFCFIAFASL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2296_THEVB
Sequence: MTVAYFDCPAGVAGDMCLGALLDLGVPLDYLQSQLAKLGIANEFELTTETVQRRGQRGLKAQVHLRDRHGHHHRHWPEIADQICAAHLPDRARDWSLKVFEALAIAEGAVHGIEPEKVHFHEVGAVDALVDIVGTCLGLDYLDVRQVYCSALPTGGGTVKAAHGQLPVPVPAVLELCQRYRVPLYSNGIEKELVTPTGAALVCALSAGFGAPPAMTLQRVGLGAGTQELPLPNLLRLWLGTVPAPPETGTAKTIVELQTQLDDMPPQALSYACEQLYAAGALEVFCQPITMKKSRLGVLVTVLCPPSAEAACVQTLFRETTTLGLRRQVQERYILERQMREIPTPFGTVRVKVAEHQGQRLNVQPEYEDCAALARQHQQPWQVVYQEALAVALKLWPLG
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: FRG2B_HUMAN
Sequence: MGKGNEDPDLHCSSIQCSTDQPPFQQISFTEKGSDEKKPFKEKGKTAFSHSSEKHIQRQGSEPNPNKENSEETKLKAGNSTAGSEPESSSYRENCRKRKMSSKDSCQDTAGNCPEKECSLSLNKKSRSSTPVHNSEIQETCDAHHRGRSRACTGRSKRHRSRALGVQTPSIRKSLVTSVRAMSEAVYQDLAQVWAQQIHSPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGPGESALDREAHPFPGQEITETVSGSDEAKL
What are the official names of this protein?
Protein FRG2-like-1, FSHD region gene 2 protein family member B, HSA10-FRG2.
What is the protein family that this protein belongs to?
Belongs to the FRG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_SALAI
Sequence: MEKFTIHTGTAAPLRRSNVDTDQIIPAVYLKRVTRTGFADGLFSGWREDQGFVLNDESYSDASILVAGPEFGTGSSREHAVWALRDWGFRAVLSPRFGDIFRGNALKGGLLPVELELEAIEEIWNRVEADPRTPVTVDLDARQVRVGEATWSFALDEFSRWRLMEGLDDIGLTLRHEVVIGDFEASRPPFLPTVT
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: XKR9_PANTR
Sequence: MKYTKQNFMMSVLGIIIYVTDLIVDIWVSVRFFHEGQYVFSALALSFMLFGTLVAQCFSYSWFKADLKKAGQESQHCFLLLHCLQGGVFTRYWFALKRGYHAAFKYDSNTSNFVEEQIDLHKEVIDRVTDLSMLRLFETYLEGCPQLILQLYILLEHGQANFSQYAAIMVSCCAISWSTVDYQVALRKSLPDKKLLNGLCPKITYLFYKLFTLLSWMLSVVLLLFLNVKIALFLLLFLWLLGIIWAFKNNTQFCTCISMEFLYRIVVGFILIFTFFNIKGQNTKCPMSCYYIVRVLGTLGILTVFWVCPLNIFNPDYFIPISITIVLTLLLGILFLIVYYGSFHPNRSAETKCDEIDGKPVLRECRMRYFLME
What is the function of this protein?
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface.  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.
What are the official names of this protein?
XK-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPG_CLOP1
Sequence: MEKREFKAESKRLLDIVINSIYTNREIFLRELISNASDAIDKVYYKTLGDSSLTFNKDDYYIKIKPNKEERTLTISDKGIGMTEKELDENLGVIAKSGSLQFKKENEIKDGFDIIGQFGVGFYSGFLVADKITVITKAFGADKAYKWESDGVDGYTISEAEKDSFGTDIILHLKANDEDENYDEFLEEYKLKSLIKKYSDFIRYPIKLDVTKSRVKEGTENEHEEYVEEETVNSMVPLWRRNKNELTDDDYNNFYVEKRFGFDKPLRHMHISVDGMISYNSILYIPENIPYDYYTKEYEKGLELYSNGVLIMEKCSELLPDYFGFVKGIVDSQDLSLNISREMLQHDRQLSRIAKNIKTKIKNELESMMKNDRESYEKFYKSFGRQLKYGVYDDFGMNKDELKDLLMFYSSKEKKMVSLAEYVERMAEDQKYIYYAVGESNERIEKMPQTEMVLDKGYEILYFTEDVDEFAIKMLMNYKEKEFKSVSSGDLGIESEEENKKENEENKGIFEAMKEALGEKISAVKASSRLKNYPVCLSSEGEVSIEMEKILSAMPNNQGVKAQKVLEVNTNHEVFNSLKDALENDKDKFNLYTKLLYNQALLVEGLSIEDPVDFTNDICKLMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNER_BACSU
Sequence: MNMTINEDALNWYKEELDLESGDQVRFFVRYGGCSNVQKGFSLGVAKDAPQEAGVTAEADGITFFIEESDLWYFDNHDLLVSYSEDADEPVFEYQ
What are the official names of this protein?
Uncharacterized protein YneR.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: GT20_ARATH
Sequence: MVSKRKSRTSKTIEDSCIHLCSVFFRFLYYTLPALFLFFFLLYLCLSFTTGISYNNFHMCIFSRKFNDPYCNTAGSKPGFQIISEENVTFAGEIAGDRVSKDHNKILNSVPVQEHKTKNKVDLNSLIELKAEEEYSKYIKPTSEDEGYALRAAIKYLYLQRSWLSPGDENLNKPRSCEGKGVYVYDLPSKFNSDLLVGCNDILPGVNLCSYFKNEGFGEAIKNLGKGWFATHMYSLEPILHSRVLKHPCRVYNETQAKLFFVPYYGGYDVLRWHYRNVSEDVKDRLGIEVLKWLNSKESWRRNAGKDHVFVLGKITWDFRRDKDPWGSRFLELQEMQNPTKLLIERQPWQVNDIAIPHPTYFHPRTDDDITRWQIKIMSKLRRNLVSFAGGARPDNPNNIRSTLIEQCISSNQCRFLNCTNESCTNPKNVLDLFQDSEFCLQPPGDSATRRSVFDSLISGCIPVIFTPYTAYYQYAWHLPEDHRKYSVYISEQDVKEKRVNVVEILKAKTLKEKKDMKSYIVQQLLPGLVYGDSNAKFEKFRDAFDITFDCLLKKINRSVV
What is the function of this protein?
Functions in xyloglucan synthesis by adding side chains to the xylosylated glucan backbone.  Involved in the galactosylation of hemicellulose xyloglucan.
What are the official names of this protein?
Probable xyloglucan galactosyltransferase GT20, Glycosyltransferase 20, AtGT20.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RL22_CHRSD
Sequence: MEVTAKLRGARLSAQKARLVADLVRGKPVAEALDVLAYSPKKAAKVVKKVLQSAIANAEENNGMDIDELRVSTICVDEGMTLKRIQPRAKGRADRILKRTCHITVKVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SC11C_CANLF
Sequence: MVRAGAVGTHLPASGLDIFGDLRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:3511473, PubMed:8444896, PubMed:14559916).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11C, Microsomal signal peptidase 21 kDa subunit, SPase 21 kDa subunit, SEC11 homolog C, SEC11-like protein 3, SPC21.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: DRDA_BACT7
Sequence: MLLQKEREEIVAYGKKMISSGLTKGTGGNISIFNREQGLVAISPSGLEYYETKPEDVVILNLDGEVIEGERKPSSELDMHLIYYRKREDINALVHTHSPYAKTIASLGWELPAVSYLIAFAGPNVRCAPYETFGTKQLADAAFEGMIDRRAVLLANHGLIAGANNIKMAFTVAEEIEFCAQIYYQTKSIGEPKLLPEDEMENLAKKFEGYGQQ
What is the function of this protein?
Catalyzes the cleavage of 5-deoxy-D-ribulose 1-phosphate to yield dihydroxyacetone phosphate (DHAP) and acetaldehyde, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.  Is also able to catalyze the reverse reaction, using several aldehydes as substrate, with acetaldehyde being the preferred substrate.
What are the official names of this protein?
5-deoxy-D-ribulose 1-phosphate aldolase, 5-deoxyribose disposal aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family.
Protein: SAA3_RABIT
Sequence: MKLSIGIIFCFLILGVNSREWLTFLKEAGQGAKDMWRAYSDMKEANYKNSDKYFHARGNYDAAKRGPGGVWAAEVISDARENYQKLIGRGAEDSKADQEANQWGRSGNDPNHFRPKGLPDKY
What is the function of this protein?
Major acute phase reactant.  Apolipoprotein of the HDL complex.  In vitro exhibits antimicrobial activity against Escherichia coli, Streptococcus uberis and Pseudomonas aeruginosa (By similarity).
What are the official names of this protein?
Serum amyloid A-3 protein.
What is the protein family that this protein belongs to?
Belongs to the SAA family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF12A_XENLA
Sequence: MESADSTGKGSIEQSESQRQSQMDRLDREEAFYQFVNNLNEDDYRLMRDNNLLGTPGEITKEELLRRLQQIKEGPPQPSTEETRGDSVSTGGDPAEDSSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRTSGNPSMPSLDQSAEMPGAEDMEVSSQGEAENEPEPIPIATRSAPAEVTVEEAPIQRGQRRARSRSPDQRRTRARTDRSRSPLHHAVDPPIRRAPHSSSQTVDTSNTEEAEGSSRTRHHVSSQVQNSSSSNETEGSSRTRQHIPARQQVLGTEGQSQSTVHLSNPETRSSSQTPQTDSSTNAETTGTGQRPPTIVLDLQVRRVRPGDYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYNDNDTDPNNPTAVSPTAAVPGEAQNNANAEVRAPSAEPTEPVAPVETDEGSNVSTTATRREGRNSRGAVTFEESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHIHCIDRWLSENSTCPICRRAVLVASNRESIV
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase specific for ldb1, mediating ubiquitination and proteasome-dependent degradation of excess ldb1 in a RING-dependent manner.  Does not degrade ldb1 bound to lhx1/lim1, nor lim1 itself and thus contributes to the establishment of proper ldb1-lhx1/lim1 stoichiometry and the formation of a ldb1-lhx1/lim1 complex.  Interferes with Spemann organizer function and suppresses secondary axis formation induced by ldb1 and lhx1/lim1.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF12-A, RING finger protein 12-A, RING-type E3 ubiquitin transferase RNF12-A, XRnf12.
What is the protein family that this protein belongs to?
Belongs to the RNF12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URED_RHOP2
Sequence: MIQAETSAADSAVFAGNRAQGAVRFDVRAVDGVTRRGQLHESGSLRVRFPSPEQQGLSAVLVNTAGGIAGGDRFGVDIAVGESARLTLTTAAAEKIYRSHGPAAQLDIALQVAEGGHLAWLPQETILFDQARVERRIDIDLAAGASLLLCESVIFGRSAMGETMRSGRFTDRWRLRIGGKLVFAETVRLDGDIGALLGRPAVAKGGVAIGTALIAPGDAALVARLREDADGFGAEVGITAWNGIAMARFCAQDAAKLRADMMAVLRRAAGRALPRLWLG
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK15_HUMAN
Sequence: MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGLQAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLASYQKGHHPAQFSKCW
What is the function of this protein?
Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
What are the official names of this protein?
Cyclin-dependent kinase 15, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein, Cell division protein kinase 15, Serine/threonine-protein kinase ALS2CR7, Serine/threonine-protein kinase PFTAIRE-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: PNCB2_MYCTO
Sequence: MAIRQHVGALFTDLYEVTMAQAYWAERMSGTAVFEIFFRKLPPGRSYIMAAGLADVVEFLEAFRFDEQDLRYLRGLGQFSDEFLRWLAGVRFTGDVWAAPEGTVIFPNEPAVQLIAPIIEAQLVETFVLNQIHLQSVLASKAARVVAAARGRPVVDFGARRAHGTDAACKVARTSYLAGAAGTSNLLAARQYGIPTFGTMAHSFVQAFDSEVAAFEAFARLYPATMLLVDTYDTLRGVDHVIELAKRLGNRFDVRAVRLDSGDLDELSKATRARLDTAGLEQVEIFASSGLDENRIAALLAARCPIDGFGVGTQLVVAQDAPALDMAYKLVAYDGSGRTKFSSGKVIYPGRKQVFRKLEHGVFCGDTLGEHGENLPGDPLLVPIMTNGRRIRQHAPTLDGARDWARQQIDALPPELRSLEDTGYSYPVAVSDRIVGELARLRHADTAEAHPGSNVVGAKAKRP
What is the function of this protein?
Involved in the Preiss-Handler pathway, which is a recycling route that permits the salvage of free nicotinamide (NM) and nicotinic acid (Na) involved in the NAD biosynthesis.  Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.  It is not able to use nicotinamide.  PncB2 appears to be responsible for the increased salvage synthesis of NAD during infection of host tissues (By similarity).
What are the official names of this protein?
Nicotinate phosphoribosyltransferase pncB2, NAPRTase pncB2.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: MUTS_CHLFF
Sequence: MTSKKLTPMMKQWHQCKEQAGESLLLFRMGDFYEAFYEDAVLLSQHLDLTLTQRQGIPMSGIPVSTINGYIDRLVSKGFKVAVAEQLDEVQDGKGKSEPLSRELQRFITPGTLLSSSLLPEKAHNYIVSINRVGALFGFSCLDFSTGSFLLQEYDNKKDLIDEICRLAPTEILSCDKFYKKHSDVIEQLLQHLKLTLSTYSDWAFEHQFATQKLSAHFKVSSLDGFGLKGLVPAINAAGALLSYLQDKLLLPIEHISIPKTHGNQKYLLVDTASQVNLELLAPLHDPQGKSSLLHVMERTCTPMGGRLLRNTLVSPFYDQKEILLRQDAVEFLLNRSELRKNLRSFLSQVRDLERLTTRVTTSLASPKDVGMLRDSLHASIRVFEVLSPLPLPEFFQGKFIPTIGLASLLDLLSKALLGELPLRISEGNIFSDDYHPDLKRLRYTRENSKEWLWDYQETIRKQTGVKKLKVCYSQALGYYIEVSSDLAPLLPKEFIRRQSRLHAERFTTEKLQEFQDDMLHVSDKLQMLETELFKDLCSRILEQREAILSLSQVIADVDYILSLADLAAEHNYCRPVVDSSDSLAILGGIHPVAQTLLDRGTFIPNDIKMHSTRTRMILITGPNMAGKSTYIRQIALLVIMAQMGSFIPAKSAHIGMIDKIFTRIGAGDNLSKGMSTFMVEMAETANILHNATDRSLVILDEVGRGTSTYDGLAIAQSVVEYLLFTEGKKAKTLFATHYKELTDLEKHCPHVENFHAGVKENGGQPVFLYEILKGHSQRSFGIHVAKLAGFPLCVVSRAQQILRQLEGPEAASRQNQEKVQQLTLF
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: XYLB_STRRU
Sequence: MSAAEGPLVVGVDTSTQSTKALVVDVATGRVVASGQAPHTVTSGAGRESDPRQWWDALCEALRQCGEAAHEAAAVSIGGQQHGLVTLDGHGEPVRPALLWNDVRSAPQGHRLIEELGGAKFWAERTGSVPAASFTVTKWAWLAEHEPEAVRATRAVRLPHDYLTERLTGQGTTDRGDASGTGWWASGTEAYDEEILGHVGLDPALLPRVVRPGEVAGTVRDSHELPFSKGTLVACGTGDNAAAALGLGVRPGTPVMSLGTSGTVYAVTQRRPADPTGTVAGFADARGDWLPLACTLNCTLAVDRVAALLGLDREAVEPGHGVTLLPFLDGERTPNLPRSSGLLHGLRHDTTGGQLLQAAYDGAVYSLLAALDLVLDEDADPSAPLLLIGGGARGTAWQQTVRRLSGRAVQVPRAAELVALGAAAQAAGLLTGEDPAAVARRWETAAGPVLEAVERDEETLDRLAGVLSDAAPLLERGTGAG
What is the function of this protein?
Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.
What are the official names of this protein?
Xylulose kinase, Xylulokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.