PharMolix/UniProtQA huggingface dataset:
Protein: OEP61_ARATH
Sequence: MFNGLMDPEMIRLAQDQMSRMTPADFARIQQQMMSNPDLMNMATESMKNMRPEDLKQAAEQLKHTRPEDMAEISEKMAKASPEDIAAMRAHADAQFTYQINAAQMLKKQGNELHSRGNFSDAAEKYLRAKNNLKEIPSSKGGAILLACSLNLMSCYLKTNQHEECIKEGSEVLGYDARNVKALYRRGQAYRDLGLFEDAVSDLSKAHEVSPEDETIADVLRDVKERLAVEGPGKASRGVVIEDITEENNVTSGENKKPSKEANGHAQGVKTDVDGLQALRDNPEAIRTFQNFISKTDPDTLAALSGGKAGDMSPDMFKTASSMIGKMSPEEIQKMVQTASSFKGDNPFAPTAPSTENGFTPTPDMLKLASDMMGKMSPEERERMFNMASSLKANAPASTSYGNAEASEPRESLGASGSSSGNSFVAPRSGFEPSIPSAPPADLQEQMRNQMKDPAMRQMFTSMIKNMNPEMMASMSEQFGMKLSQEDAAKAQQAMASLSPDALEKMMRWADRAQTGMEKAKKAKKWLFGKGGLIFAILMLVLAMVLHRLGYIGN
What is the function of this protein?
Plays a role in protein import into the endoplasmic reticulum (ER).  May function as chaperone docking protein during post-translational protein translocation into the ER.  Chaperone receptor mediating Hsp70-dependent protein targeting to chloroplasts.  Interacts specifically with some chloroplast precursors, but not with mitochondrial precursors.  Able to select precursors for delivery to the chloroplast translocase independently of Hsp70.
What are the official names of this protein?
Outer envelope protein 61, Tetratricopeptide repeat domain-containing protein 7.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Plastid, chloroplast outer membrane; Single-pass membrane protein. Note=Resides most likely exclusively in the ER membrane.
Protein: TRAG5_ECOLX
Sequence: MKIKMNNAVGPQVRTAKPKPSKLLPVLGAASMVGGLQAATQFFAHTFAYHATLGPNVGHVYAPWSILHWTYKWYSQYPDEIMKAGSMGMLVSTVGLLGVAVAKVVTSNSSKANEYLHGSARWAEKKDIQAAGLLPRERNVLEIVTGKAAPTATGVYVGGWQDKDGNFFYLRHSGPEHVLTYAPTRSGKGVGLVVPTLLSWGASSVITDLKGELWALTAGWRQKHAKNKVLRFEPASTSGGVCWNPLDEIRLGTEYEVGDVQNLATLIVDPDGKGLDSHWQKTAFALLVGVILHALYKAKDDGGTATLPSVDAMLADPNRDIGELWMEMATYGHVDGQNHHAIGSAARDMMDRPEEEAGSVLSTAKSYLALYRDPVVARNVSRSDFRIKQLMHEDDPVSLYIVTQPNDKARLRPLVRVMVNMIVRLLADKMDFEGGRPVAHYKHRLLMMLDEFPSLGKLEIMQESLAFVAGYGIKCYLICQDINQLKSRETGYGHDESITSNCHVQNAYPPNRVETAEHLSRLTGQTTVVKEQITTSGRRTAAMLGQVSRTYQEVQRPLLTPDECLRMPGPKKNAQGEIEEAGDMVIYVAGYPAIYGKQPLYFKDPVFSARAAIPAPKVSDRLRAVAQADTEGEGITI
What is the function of this protein?
Required for conjugative transfer of plasmid R751.  Binds tightly and specifically to the relaxase TraI.  Can also bind to DNA without sequence specificity.  May form a pore-like structure that could serve as a channel for DNA transfer (By similarity).
What are the official names of this protein?
Conjugal transfer protein TraG.
What is the protein family that this protein belongs to?
Belongs to the VirD4/TraG family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BRDT_XENTR
Sequence: MSMSSRHLHSSIVNPPPPEYINRKKTGRLTNQLQYLEKVVLKALWRHHFSWPFQQPVDAAKLNLPDYYQIIKNPMDLSTIRKRLEYNYYSKALDCIQDFNTMFTNCYIYNKPGDDIVVMSQELEKVFMEKIAEMPHEEIELSVVGNRGVKSRIKISAVAAEVCKKKMVSQKMHRRTFPCPVIAMMPKRTTLVPLSVIRSSTSSHSASSVSKVNKGIKRKADTTTPAVSLIATSCESSPTLSEPKPNKILSGTEKTRSAETSAVDLPDSQHHIHFIKSNQICEQLKHCNNILNEMMSKKHAEYAWPFYKTVIPTSLLDCSDAIKHPMDLATIRDKMENGLYKDTQDFASDVRLMFMNSYKYNPPDNEVVNMARKMQDVFEGMFAKIPDDPLATQSMVERYKTSTEESSSSSSSEQSSSSDSEDERAQHLALLQEQLRAVQEQLKALTETPIFSKIQPKSAVGVYDKYKQWVKCIEPMGKLLKRKKNYDAKKKKLHVSDEEEDVKPMSYDEKRQLSLDINKLPGEKLGRIVHIIQSREPSLKDSNPNEIEIDFETLKQSTLRHLEKYVMVCLRKRPKKPSSIKSLKSKEQLNKEKKQELEKRLRDVSGQLSSAKKPKIQGFLYPMQSIGGPSRLSESSTSSSASDVSNSSDSSSSDSSDSESATFPKNILAKKQTSTNYEVPLLLYYGCFVNKPRTSIPQNGLCIGSQSLAYTTISTIVHPTPMALMPLHPGSTNYTSLQLLLKYGLHVPLIIENPLGNSVLFENYLEVLHPSQIEQTFAIKEECLKPKYKNAKVKTSFCWEVFSKSLATTHVTIKSSSNSFQQFRKAAIAKEERERALKAQELRRLEDSKAGMQEKLSPSLPMETKVHEMQAQTIDEATKGEPTCNPVHEGITEEERNLARMREQERRRREAMAGTIDMYLQSDIMATFEEHLC
What is the function of this protein?
Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis.  Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time.  In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA.  Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac).
What are the official names of this protein?
Bromodomain testis-specific protein.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin.
Protein: PURQ_HALH5
Sequence: MKFAVIVFPGSNCDADMYHAVKDALGEEVDYLWHTETSVEGYDAILLPGGFSYGDYLRSGSIARFSPIMEDVIRAANEGVPVLGVCNGFQVLLEAGLLPGAMLRNEKLTFICKPVELEVQNNDTFFTSEYEQGETITIPVAHGEGNYYCDDETLKQLEANNQVVFRYTDRVNGSRNHIAGIVNKAGNVLGMMPHPERAVEQLVGGEDGLRLFKSILRNWRESHVVTP
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
Protein: SBT41_ARATH
Sequence: MAIAFHTFLLQLLLFFFASFAEANDSRKTYLVQMKVGGHRYGSSSGHQELLGEVLDDDSTLADAFIYSYKESFTGFSASLTPRERQKLMRRREVLEVSRSRNLKLQTTRSWDFMNLTLKAERNPENESDLVVAVIDSGIWPYSELFGSDSPPPPGWENKCENITCNNKIVGARSYYPKKEKYKWVEEKSVIDVTGHGTHVASIVAGRKVEKAGYFGLAEGTMRGGVPNAKIAVYKTCWRVIRKNGREDSVCREDNILKAIDDAIADKVDIISYSQGFQFTPLQKDKVSWAFLRALKNGILTSAAAGNYANNGKFYYTVANGAPWVMTVAASLKDRIFETKLELEGEDKPIIVYDTINTFETQDSFYPLLNEKAPPESTRKRELIAERNGYSILSNYDEKDKGKDVFFEFAQINLLDEAIKEREKGAIVLGGKSYDFNESIKLQFPIASIFLDEQKKGKLWDYYKKDQSKERLAKIHKTEEIPREEGWVPTVAHLSSRGPNCDSFLANILKPDIAAPGLDIIAGWPENVKLSSDRPANDYRHLRFNIMSGTSMACPHATGLALYLKSFKRWSPSAIKSALMTTSSEMTDDDNEFAYGSGHLNATKVRDPGLVYETHYQDYIDYLCKLGYNTEKLRSHVGSDKIDCSKTEIDHDADLNYPTMTARVPLPLDTPFKKVFHRTVTNVNDGEFTYLREINYRGDKDFDEIIVDPPQLKFSELGETKTFTVTVTGISKRNWNKNRAFMTRNTWLTWTEKDGSRQVRSPIVIYSIKGPKACM
What are the official names of this protein?
Subtilisin-like protease SBT4.1, Subtilase subfamily 4 member 1, AtSBT4.1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPVC_SALTM
Sequence: MPINRPNLNLNIPPLNIVAAYDGAEIPSTNKHLKNNFNSLHNQMRKMPVSHFKEALDVPDYSGMRQSGFFAMSQGFQLNNHGYDVFIHARRESPQSQGKFAGDKFHISVLRDMVPQAFQALSGLLFSEDSPVDKWKVTDMEKVVQQARVSLGAQFTLYIKPDQENSQYSASFLHKTRQFIECLESRLSENGVISGQCPESDVHPENWKYLSYRNELRSGRDGGEMQRQALREEPFYRLMTE
What is the function of this protein?
Secreted effector that irreversibly inactivates host MAP kinases by catalyzing the dephosphorylation of the phosphothreonine residue in the pT-X-pY motif present in MAPKs, via a beta-elimination reaction leading to a dehydrobutyrine residue.
What are the official names of this protein?
MAPK phosphothreonine lyase, 28 kDa virulence-associated polypeptide, Mouse killing factor, Secreted effector protein SpvC, Virulence protein MkfA.
What is the protein family that this protein belongs to?
Belongs to the phosphothreonine lyase family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBEY_STACT
Sequence: MFTIDFTDHTGEVNSEWYQQIDNLLTFAKKEEKIEDDAELSVTFVNKQEIQEINRDYRNKDKVTDVISFALEEDEPDIEGLDMPRVLGDIIICADVAKEQAEEYGHSFERELGFLALHGFLHLLGYDHMNEADEKEMFGRQKLILDNYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUZ_NEONM
Sequence: MRINISLSSLFERLSKLSSRSIAITCGVVLASAIAFPIIRRDYQTFLEVGPSYAPQNFRGYIIVCVLSLFRQEQKGLAIYDRLPEKRRWLADLPFREGTRPSITSHIIQRQRTQLVDQEFATRELIDKVIPRVQARHTDKTFLSTSKFEFHAKAIFLLPSIPINDPLNIPSHDTVRRTKREIAHMHDYHDCTLHLALAAQDGKEVLKKGWGQRHPLAGPGVPGPPTEWTFLYAPRNEEEARVVEMIVEASIGYMTNDPAGKIVENAK
What is the function of this protein?
Luciferase; part of the gene cluster that mediates the fungal bioluminescence cycle (PubMed:30478037, PubMed:28508049).  Uses the fungal luciferin 3-hydroxyhispidin as a substrate to produce an endoperoxide as a high-energy intermediate with decomposition that yields oxyluciferin (also known as caffeoylpyruvate) and light emission (PubMed:30478037, PubMed:28508049).  The fungal bioluminescence cycle begins with the hispidin synthetase that catalyzes the formation of hispidin which is further hydroxylated by the hispidin-3-hydroxylase, yielding the fungal luciferin 3-hydroxyhispidin.  The luciferase then produces an endoperoxide as a high-energy intermediate with decomposition that yields oxyluciferin and light emission.  Oxyluciferin can be recycled to caffeic acid by caffeoylpyruvate hydrolase (PubMed:30478037) (Probable).
What are the official names of this protein?
Luciferase, Fungal bioluminescence cycle protein luz.
What is the protein family that this protein belongs to?
Belongs to the fungal luciferase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: SPEE_ECOLI
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Involved in the biosynthesis of polyamines which play a significant role in the structural and functional organization in the chromoid of E. coli by compacting DNA and neutralizing negative charges.  Catalyzes the irreversible transfer (ping-pong mechanism) of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.  Cadaverine (1,5-diaminopentane) and spermidine can also be used as the propylamine acceptor.
What are the official names of this protein?
Polyamine aminopropyltransferase, Cadaverine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine aminopropyltransferase, Spermidine synthase, SPDS, SPDSY, Spermine synthase, Thermospermine synthase.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA1_MOUSE
Sequence: MVGHLSEGAIEVMIQQENTSIKPILQVINIRPISTGNRSPRYRLLMSDGLNTLSSFMLATQLNTLVEGGQLASNCVCQVHKFIVNTLKDGRKVVVLMDLEVMKSAEDVGLKIGNPVPYNEGYGQQQQQQQQQQQQAVPSPASAATPPASKPQPQNGSLGMGSTAAKAYGASKPFGKPAGTGLLQPSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGALKIANKQFSAVKNDYEMTFNNETSVLPCEDGHHLPTVQFDFTGIGDLESKAKDALVDIIGICKSYEDSIKITVKSNNREVAKRNIYLMDMSGKVVTTTLWGEDADKFDGSRQPVMAIKGARVSDFGGRSLSVLSSSTVIVNPDIPEAYKLRGWFDSEGQALDGVSISDHRSGGAGGGNTNWKTLHEAKSENLGQGDKADYFSTVAAVVFLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDREFPNFKYRMILSANIADFQENQWVTCFQESAEAILGQNTMYLGELKEKNEQAFEEVFQNANFRSFTFRIRVKLETYNDESRIKATVMDVKPVDFRDYGRRLIANIRKNM
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.  In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.  Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response.  It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.  Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair.  Also plays a role in base excision repair (BER) probably through interaction with UNG.  Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage.  May also play a role in telomere maintenance.
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: DAPE_HELPJ
Sequence: MDALEITQKLISYPTITPKECGIFEYIKSLFPAFKTLECEKNGVKNLFLYRIFNPLKKHAEKEHAKEKHVKENVKPLHFCFAGHIDVVPPGNNWQSDPFKPIIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTRLMLEKLKEKDLLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGVQGHVAYPQKCQNPIDTLASVLPLISGVHLDNGDECFDPSKLVITNLHAGLGANNVTPGSVEIAFNARHSLKTTQESLKEYLEKVLKDLPYTLELESSSSPFITASHSKLTSVLQENILKTCHTTPLLNTKGGTSDARFFSAHGIEVVEFGAINDRIHAVDERVSLKELELLEKVFLGVLEGLSEK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: XSC_ROSNI
Sequence: MLFRASQPEDKPMKMTTEEAFVKTLQMHGIQHAFGIIGSAMMPISDIFGKAGITFWDCAHEGSGGMMADGYTRATGKMSMMIAQNGPGITNFVTAVKTAYWNHTPLLLVTPQAANKTMGQGGFQEVEQMAAFKDMVCYQEEVRDPTRMAEVLNRVILNAKRYSAPAQINVPRDYFTQVIDIELPKIVDFERPSGGEEALDEAAKLLSEAKFPVILNGAGVILAGAIPATAELAERLDAPVCCGYQHNDAFPGSHPLHAGPLGYNGSKAGMELISKADVVLALGTRLNPFSTLPGYGIDYWPKDAKIIQVDVKPERIGLTKPVAVGIVGDAKKVAKTILAKLSDTAGDADREERKATIAKTKSAWAQELSSMDHEQDDPGTTWNERARGAKPDWMSPRMAWRAIQAALPKEAIISSDIGNNCAIGNAYPSFEEGRKYLAPGLFGPCGYGLPAVVGAKIGCPDTPVVGFSGDGAFGIAVNELTAIGRGEWPAVTHVVFRNYQWGAEKRNSTLWFDDNFVGTELDEQVSYAGIAKACGLKGVVARTMDELTDALDQAIKDQKAGTTTLIEAMINQELGEPFRRDAMKKPVAVAGIDPADMREQQVD
What is the function of this protein?
Catalyzes the degradation of sulfoacetaldehyde into sulfite and acetyl phosphate.  Involved in sulfolactate degradation.
What are the official names of this protein?
Sulfoacetaldehyde acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: LPXD_ANADF
Sequence: MTFTLAELASRVGGEVVGDGALVVEGVAPLEDAGPHDVSFFSNRKYRKAFEASRAGVVVVEPDAEIPAGRTVLRARNAYLAFAKISTLFHPPQEPLPEIAPEAVIHPSARVHPSAQVMPLASIGPDAVIGARTIVHPGVHVCEGARVGEDCLLYPNVVIRERCVVGNRVILQPGCVIGSDGFGFAFDPDGEGHGPRHFKVPQAGIAVVEDDVEIGANACIDRATLGATRVGRGTKIDNLVQLGHNVELGPLCLIVAQVGIAGSTKLGMGVVAAGQVGIIGHLNIGDGVKMGAQSGIAGDVAAGDTVSGTPAQPHADWLRSQAALRQLPDLRREVKELRRELDRLRAGKEGKP
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DNLJ_STAAM
Sequence: MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTVRVGGEAQASFKKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: FOLKP_CHLTR
Sequence: MTSWNFVCLSLGSNLGNRHEHIRRAYASLKKAGIRNLKSSVILETKALLLEGAPKEWDLPYFNSVVIGETQLSPDELIEEIKMIESRFGQDASLKWGPRPIDIDVLFYGDEAFSYHSDKCTIPHPKVLERPFLLSMIASLCPYRRFRLEGSSCNGKTFAELAAIYPLTEEDALGSFGSATQIMGIVNITDNSISDTGLFLEARRAAAHAERLFAEGASIIDLGAQATNPRVKDLGSVEQEWERLEPVLRLLAERWGAAQQCPDVSIDTFRPEIIRRAVEVFPIRWINDVSGGSLEMAHLAKEFGLRLLINHSCSLPPRPDCVLSYEESPIEQMLRWGESQLEQFAQVGLDTSWQVVFDPGIGFGKTPVQSMLLMDGVKQFKRVLECPVLIGHSRKSCLSMLGRFNSNDRDWETIGCSVSLHDRGVDYLRVHQVEGNRRALAAAAWAGMFV
What are the official names of this protein?
Folate synthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HPPK family.
Protein: FOSB_ALKCK
Sequence: MVNGINHMTFSVSNMDKAVSFYKHVFMEAPLVLGEKTAYFTIGGTWLALNLQPDIDRKEIRQSYTHIAFSIEESQLDAFYTRLLEAGADILPGRKRQVETEGKSIYFRDPDGHLLEVHTGTLAERLAHYEKTAPDMLVNIDEQNKK
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y659_SINMW
Sequence: MPAFAIYFLAALAEIAGCFTFWAWLRLGKSGLWLLPGMASLAIFAWLLTMVDTPAAGRAYAAYGGIYIIASLCWLWVAEGARPDRWDMTGAAVALAGSAIILAGPR
What are the official names of this protein?
UPF0060 membrane protein Smed_0659.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPE_ECO24
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: U91_HHV6Z
Sequence: MMGYEEKVSATGKTRLKILACLIVLILAAAITMLTLEIISNQKRTTTDLEAVTVALKHVSTSLANCTESTTSVHTANPRKNKESRKKIEGKSPSWVQALTTASGIILLFCIMMIFITCSWTTEKDTEKSEVQSYASSVETLDSLNEAIIPKTEMNV
What are the official names of this protein?
Protein U91.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: U119A_HUMAN
Sequence: MKVKKGGGGAGTATESAPGPSGQSVAPIPQPPAESESGSESEPDAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP
What is the function of this protein?
Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins.  Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons.  Probably plays a role in trafficking proteins in photoreceptor cells.  Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
What are the official names of this protein?
Protein unc-119 homolog A, Retinal protein 4, hRG4.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells.
Protein: PGLR_RHIRD
Sequence: MALATRATGGAGRRKPVRARCARGLHLVSCHKTQLLGFTIRNAASWTIHPQGCEDLTAAASTIIAPHDSPNTDGFNPESCRNVMISGVRFSVGDDCIAVKAGKRGPDGEDDHLAETRGITVRHCLMQPGHGGLVIGSEMSGGVHDVTVEDCDMIGTDRGLRLKTGARSGGGMVGNITMRRVLLDGVQTALSANAHYHCDADGHDDWVQSRNPAPVNDGTPFVDGITVEDVEIRNLAHAAGVFLGLPDVPSATSLSATSPIVSHDPSAVATPPIMADRVRPMRMRLVFEQADVVCDDPALLNDAPVSISSYFD
What is the function of this protein?
Seems to regulate the surface properties of the bacterium in the presence of plant cells or plant cell extracts.
What are the official names of this protein?
Polygalacturonase, PGL, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY_ECOUT
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCTP_THEPA
Sequence: MKVYKDLYSNDEVCSDAYDHHDPFDNADLSSVAFEVKTSKVPKGEEDYGIGYNDEEGADQMNVDPNVEMVVDVVDKFGLQSLSLTKKDYSSYIRKYIQRLVATLQEKNPERVEPFKTTVSDFVKHVLANFEDFEFYVGESLDYEAGLVYAYYKGEEVSPRLVFLKDGLVEERY
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.