PharMolix/UniProtQA huggingface dataset:
Protein: PALM_MOUSE
Sequence: MEVLATDTASQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARGLEESITRLEKEIDVLEFGESAPAASKENSAAPSPGRPQSASPAKEEQKSETLVNAQQTPLGTPKENRTSTPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTVLPRDPLPQGVKVYEDETKVVHAVDGIAENGIQPLSSSEVDELIHKADEVTLSEAGSTAGPAEPRGLAEDVTRTTPSRREITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDTIKAELVVIEDAATPREPAPLNGSAAELPATKEENQTGPTTTPSDTQDLDMKKPRCRCCSVM
What is the function of this protein?
Involved in plasma membrane dynamics and cell process formation.  Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner.
What are the official names of this protein?
Paralemmin-1, Paralemmin.
What is the protein family that this protein belongs to?
Belongs to the paralemmin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, filopodium membrane; Lipid-anchor. Cell projection, axon. Cell projection, dendrite. Cell projection, dendritic spine. Basolateral cell membrane; Lipid-anchor. Apicolateral cell membrane; Lipid-anchor. Note=Translocation to the plasma membrane is enhanced upon stimulation of neuronal activity.
Protein: DSG2_HUMAN
Sequence: MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEKKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCGKGAKGFTPIPGTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGPSQPQSLIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSGAGVPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
What are the official names of this protein?
Desmoglein-2, Cadherin family member 5, HDGC.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: RELE_MYCTU
Sequence: MSDDHPYHVAITATAARDLQRLPEKIAAACVEFVFGPLLNNPHRLGKPLRNDLEGLHSARRGDYRVVYAIDDGHHRVEIIHIARRSASYRMNPCRPR
What is the function of this protein?
In combination with RelB represses its own promoter.  Has been seen to bind DNA in complex with cognate antitoxin RelB but not alone.
What are the official names of this protein?
Toxin RelE, Putative endoribonuclease RelE.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: ALL8_OLEEU
Sequence: MAANTDRNSKPSVYLQEPNEVQGVFNRFDANGDGKISGDELAGVLKALGSNTSKEEIGRIMEEIDTDKDGFINVQEFAAFVKAETDPYPSSGGENELKEAFELYDQDHNGLISSVELHKILTRLGERYAEHDCVEMIKSVDSDGDGYVSFEEFKKMMTNKSGNNSQAEPPK
What are the official names of this protein?
Calcium-binding allergen Ole e 8, PCA18/PCA23.
Protein: PGM5_HUMAN
Sequence: MEGSPIPVLTVPTAPYEDQRPAGGGGLRRPTGLFEGQRNYLPNFIQSVLSSIDLRDRQGCTMVVGSDGRYFSRTAIEIVVQMAAANGIGRLIIGQNGILSTPAVSCIIRKIKAAGGIILTASHCPGGPGGEFGVKFNVANGGPAPDVVSDKIYQISKTIEEYAICPDLRIDLSRLGRQEFDLENKFKPFRVEIVDPVDIYLNLLRTIFDFHAIKGLLTGPSQLKIRIDAMHGVMGPYVRKVLCDELGAPANSAINCVPLEDFGGQHPDPNLTYATTLLEAMKGGEYGFGAAFDADGDRYMILGQNGFFVSPSDSLAIIAANLSCIPYFRQMGVRGFGRSMPTSMALDRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTGSDHLREKDGLWAVLVWLSIIAARKQSVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTDSFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT
What is the function of this protein?
Component of adherens-type cell-cell and cell-matrix junctions (PubMed:8175905).  Has no phosphoglucomutase activity in vitro (PubMed:8175905).
What are the official names of this protein?
Phosphoglucomutase-like protein 5, Aciculin, Phosphoglucomutase-related protein, PGM-RP.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm, cytoskeleton. Cell membrane, sarcolemma. Note=Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments.
Protein: BRD4B_XENLA
Sequence: MSAETGLGTRLRATSVMGDGVEGAQMSGQQQPAQPQPQTPMMQTPPPEIARPNQPKRQTNQLQYLLKTVLKTLWKHQFAWPFQVPVDVVKLNLPDYYKIIKTPMDMGTIKKRLENHFYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEETELAVVQCKGRGRARKEQDASITPMRTRVLSGSLGDKSAVKPPVTPVSKPATPTPPAVIRAPTPPQTKPQQAHPPAITQAPISFSPIISQDVVVPTTVVPTPVPQPLANHPAVIHTAAQPAKTKKGVKRKADTTTPTTHDPLHESSPLPSDPKPPKAGPRKESGRQIRPIKKTEVPDSQLPAPPDLHPQPAPIAEKDSKTSEQLRYCAGIVREMFSKKHQAYAWPFYKPVDVETLGLHDYCEIIKHPMDLGTIKVKMENCDYKNAQDFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRFAKMPDEPEEAPAPVPSPAPGPPAPSIKIPPPTSSDTSSDSSSDSESSSDSEEERAQRLAELQEQLKAVHEQLAALSQPQPNKPKKKEREKRKEKHKRKEEVEETRKGRIREPPAKKPKKSVQVSGGTPSIKKEAPPPVTRPARPAPPPAPCESSEEDTQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQDKIEAPTSGIVKVKSYSSSESESSSESSTSDSEESDPETAPNQKKKGHSGRESRKHHHPMQQPLIAPPPVMKPPSPTLAPSYPPPSSLDSSHPSLHHPLHPANVFEAVMQLPPDLPPHLAGQTEHCSPPHLNQHALTSPPALHNAMPQQPSRPSNRAAALPTKPARPPSASPPLPPPQPHHQPPAHVHHHHHHHHHAQPPHVLLEDDGPPSPHTGLPSYLQQLHKSQQPPTQSPIHSLLTTVKVQSQAPMAAPAQSMRHHQPLVYPPPSSSASPAPSPASSHIHQMQSPPVVPQQQPAGQAPPPPQQQQQQQQQQQHPALQGTLVSSHQHHVQHQQAKQQQVIQHHHHHHPSPRQQKQETYPGGHLREAPSPLLLHSPQVPPYPGLTHPPSPQSVQPKKQEMRGALVLQPQPLVMKEDKRHSPSVRPEGFSPGMRPEPPKVPEVLKGPSHIQPRPDLKPMDGGRPVRPPDQSLPPQGMPEKEKQKQEPKTPVAPKKDLKIKNMGSWAGLMQKPPVTPTSAGKSTSDSFELFRRQAREKEERERALKHQAEQAERMRREQERMRTREDDDVQDQTRKAHEEARRRQEQQQQQQQQHVQSNLPAAPSPAQSSQPIMDQREMARKREQERRRRQAMAPSIDMNFQSELMEIFEQNLFS
What is the function of this protein?
Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation.  Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure.  During interphase, plays a key role in regulating the transcription of signal-inducible genes by associating with the P-TEFb complex and recruiting it to promoters (By similarity).
What are the official names of this protein?
Bromodomain-containing protein 4B.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with acetylated chromatin.
Protein: PYRF_LACLS
Sequence: MQENRPVIALDFPEFSDVKDFLEKFDPSEKLYIKLGMELFYTAGPQVVYYVKSLGHSVFLDLKLHDIPNTVESSMRVLARLGVDMVNVHAAGGVEMMVAAKRGLEAGTPTGRQRPKLIAVTQLTSTSEEIMQNDQKIMTSLEESVINYAQKTAQAGLDGVVCSAHEVEKIKAATSKEFICLTPGIRPEGASKGDQKRVMTPKEARTIGSDYIVVGRPITQAKDPVSAYHAIKEEWNQ
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CH602_SALTO
Sequence: MAKILSFSDDARHQLEHGVNALADAVKVTLGPRGRNVVLDKKFGAPTITNDGVTIAKEIELTDPHENLGAQLVKEVATKTNDVAGDGTTTATVLAQALVREGLRNVAAGANPTGLKRGIDAAATKVSEALLGKAVEVSDKAAIAHVATVSAQDSTIGELIAEAMERVGRDGVITVEEGSTLATELDVTEGLQFDKGFISPNFVTDAEGQESVLEDPYILITTQKISAIEELLPLLEKVLQDSKPLLIIAEDVEGQALSTLVVNALRKTMKVCAVKAPGFGDRRKAMLQDMAILTGAELVAPELGYKLDQVGLEVLGTARRVVVDKETTTVVDGGGQAADAADRVAQIRKEIEASDSEWDREKLAERLAKLSGGVAVIRAGAATEVEMKERKHRIEDAIAATKAAVEEGTIPGGGAALAQVLPALDDDLGLDGDEKVGVSIVRKALVEPLRWIAQNAGHDGYVVVQKVVDKDWGHGLDAATGEYVDLAKAGILDPVKVTRNAVANAASIAGLLLTTESLVVDKPQEPEPAAGGHGHGHQHGPGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR12_ARATH
Sequence: MFRVTGTLSAASSPAVAAASFSAALRLSITPTLAIASPPHLRWFSKFSRQFLGGRISSLRPRIPSPCPIRLSGFPALKMRASFSSGSSGSSASREILVQHLLVKNNDVELFAELQKKFLDGEEMSDLAAEYSICPSKKDGGILGWVKLGQMVPEFEEAAFKAELNQVVRCRTQFGLHLLQVLSEREPVKDIQVEELHSKMQDPVFMDEAQLIDVREPNEIEIASLPGFKVFPLRQFGTWAPDITSKLNPEKDTFVLCKVGGRSMQVANWLQSQGFKSVYNITGGIQAYSLKVDPSIPTY
What are the official names of this protein?
Rhodanese-like/PpiC domain-containing protein 12, chloroplastic, Sulfurtransferase 12, AtStr12.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PAND_ANADE
Sequence: MRRTFFKAKIHRATVTHADLEYEGSVSIDEDLLEAAGIWEYEAVHVWNITRGTRLQTYAIKGERGSGIICINGAAAHLNRPGDMVILATFAELEEAEARDFKPTVVLVDRQNKIVAKDAVEVPGPARRVTA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_CHLL2
Sequence: MARFRGSITKVSRRLGVALSPKAEKYLERRPFAPGQHGQSRKGKVSEYALQLREKQKMKYLYGILEKQFRNYYKKAVAQRGVTGDNLVKLLERRLDNVVFRSGFSASRAGARQLVSHGHLVVNGKKVNIPSFQVSPGDLIEFRQRSRNMGAVTDSLSKAPESRFPSWIQVDKANQKAVFLSVPEREDIQEPFNEQLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GUAA_SINFN
Sequence: MTQTAHPDTVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFKRLKPKAVILSGSPASTLDIGSPRAPSVIFESGLPVFGICYGQQTMCAQLGGKVESGHHREFGRAFLEVEKDCALFDGLWSLGSRHQVWMSHGDRVTALPEGFEVVATSSNAPFAFIADETRKYYAVQFHPEVVHTPDGAKLISNFVHKIAGIKGDWTMSAYRAKAVEAIRKQVGGKKVICALSGGVDSSVAALLIHEAVGDQLTCILVDHGLMRKDEAANVVAMFQEHYNLHLLHIDASDRFIGELEGVSDPETKRKIIGRLFIEVFEEEAKKLGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRELGLPESFIGRHPFPGPGLAIRCPGGISREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RRG1_YEAS8
Sequence: MAQNFGKIPSHKSYVLSLYRTVLRNIPKCCHSYAFQYEIKKTLSKQLFKHKHDKSSWSVYTLLNEFSLLNNCLLEGKLQEIKNLMKPLKKMKKQLETTKILNSLTSLGDVKTNDPEEVRRFHVLSAYIKRKQDLGLLPAYIPKTYQHKLLLPLALNEHACLKLFHIQQKLKNGPPSAGLSYTKEGRNQIWFVRSPINKGRQQSKKLGILIRKERKDSQKNIDNLNFCEINAAWALHEAIWEEYLESKKIIKVNLPKYLEYAANIPKSTKCNPSSQYQKVKEWVDPVREIMFELHSKSFQRVEYFNKYKEKLLKNGGQLAYFDKKSKEMYAKRLTLFRKMSKETLPYVTLFIEGRDLPSVLAKYGF
What is the function of this protein?
Essential for respiratory growth and required for mitochondrial protein synthesis.  Required for vacuolar acidification (By similarity).
What are the official names of this protein?
Required for respiratory growth protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PLSB_SHEB5
Sequence: MPKHDSLWLKSLRWIQKHLVHTIVVPQDPFADLNLDASRPLAYVMKTESLSDIAALSEITAKLGLPSPYEPLVANGVIAPRVVCLQGRKPLFGERAGNEPFLECFMRLLAVHKERPELDIQLVPVSLYWGRTPGKEDDTMKAAVFERENPTWLRKCLMILFLGRHNFVQFSNAVSLRYMADEHGTDMGIAHKLARVARVHFRRQRKVMTGPVLPNRQALFHSLLKSESLRKAIQEEAANKKISETQARETAIEYLDEIAADYSDSLVRIAERFLTWLWNKLYSGINIKGAEQVRQLHHDGHEIVYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPMFRRGGAFFIRRSFNGNKLYTAVFREYLDQLFAKGYSVEYFSEGGRSRTGRLLAPKTGMIAMTMNSVLRGIERPVTLVPVYLGYDHVMEVATYHKELSGKKKKKESVWQVFGAIRKLGNFGQGYVNFGEPITLQNFLNERAPNWRTELADDPEQKPSWLTPAVNVLANRVMTNINDAAAASSVTLTSLVLLATDQNALERSLLERQLDLYLTLLKKVPYTTYTSVAEGDGKHLVQQGLELNKFVVCADPLGEIVSIEASQAVSMTYYRNNIIHLFIVPSLIASCLTHNKQIPRQQVVSIVADFYPLLKAELFMGIKDVPAYVNQVLDFFIEQGLVVETDTLTVVPEHTSQLLLLASSVSETLQRYAIIFNLLANRPKMERSELESESHLLAQRLGALHGITAPEFYDKKLYGTLSVKLKELGYLADNQDKSNINRIRDQANSLLRPSVKQTIVASVTAEHTV
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRH_GRABC
Sequence: MDGTDMTEQPVYKRVLLKVSGEALMGSREYGLDKAMVQTIASDIADVVAFGVEVCLVIGGGNIFRGVSAAASGMDRAQGDYIGMLATVMNALAMQAALEKLNVPTRVQSAIPMASVCEPYVRRRAQRHMEKGRVVIFAAGTGNPFFTTDTAAALRAAEMGCNVLLKGTQVDGVYAADPRKNPDAERYNELTYLDVLSRDLSVMDAAAISLCRENHLPIIVFNIHETGAFGRVIRGEGRFTRIVETQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LY65C_RAT
Sequence: MSGLAASWSLKPLGPHGVTQALCAVLLAVLVTMNVVLGDTLLDIPSQSPPLNQYLHCYRCLLETEELGCLLGSDTCLTPLGSTCVTLHIKNSSGFNVMVSDCRNKEQMVDCSYTRASPVFGFWIFYQCCFLDFCNNPKNRKNTMH
What is the function of this protein?
May have a role in hematopoietic cell differentiation.
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G5c, Epididymal secretory protein 8, Protein RE8.
What are the subcellular locations of this protein?
Secreted.
Protein: VLTF2_VARV
Sequence: MAKRVSLPDVVISAPKAVFKPAKEEALACILPKYYKSMADMSIKTNSVIDKCWFCNQDLVFRPISIETFKGGEVGYFCSKICRDSLASMVKSHVALREEPKISLLPLVFYEDKEKVINTINLLRDKDGVYGSCYFKENSQIIDISLRSLL
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Viral late gene transcription factor 2, VLTF-2, Trans-activator protein A1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus VLTF-2/OPG126 family.
Protein: ARGD_KLULA
Sequence: MRVIRQLHTSKRLLQSLVDKQKYQATTYARPNHLVLTRGKNAILYDDVNNKEYIDFTAGIAVTALGHANPEVAEIMYKQSKKLIHSSNLYYNEECLKLSENLVEATKSFGGQYDASRVFLCNSGTEANEAALKFAKRYGILKSPSKQGIIAFQNSFHGRTMGALSVTSNPKYREPFGSLIPGVEFLNINDELTKLDQQVSSLKEKTAGLIVEPIQGEGGVFPIPLDTLVGLKKICEDHDIIVIYDEIQCGLGRSGKLWAHSYLPKEAHPDIFTTAKALGNGFPIAATVTNDKVNDILKVGDHGTTYGGNPLGSAVGNYVVNVIAEQKFLDEVNKKGEIITNRLRKLQERFPEHIKDIRGKGLMIGCDFDEAPAKIVDAARDSGLLIITAGKTTVRFVPALTIEDNLLEKGLNIFEKAVEKVYS
What are the official names of this protein?
Acetylornithine aminotransferase, mitochondrial, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS10_SPHAL
Sequence: METQNIRIRLKAFDHRVLDQATTDIADTARRTGALIRGPIPLPTRIEKFTVNRGPHIDKKSREQFEVRTHKRLLDIVQPTPQTVDALMKLDLAAGVNVEIKLA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ACA4_ARATH
Sequence: MSNLLRDFEVEAKNPSLEARQRWRSSVSIVKNRTRRFRNIRDLDKLADYENKKHQIQEKIRVAFFVQKAALHFIDAAARPEYKLTDEVKKAGFSIEADELASMVRKNDTKSLAQKGGVEELAKKVSVSLSEGIRSSEVPIREKIFGENRYTEKPARSFLMFVWEALHDITLIILMVCAVVSIGVGVATEGFPRGMYDGTGILLSILLVVMVTAISDYKQSLQFRDLDREKKKIIVQVTRDGSRQEISIHDLVVGDVVHLSIGDQVPADGIFISGYNLEIDESSLSGESEPSHVNKEKPFLLSGTKVQNGSAKMLVTTVGMRTEWGKLMETLVDGGEDETPLQVKLNGVATIIGKIGLSFAVLTFVVLCIRFVLDKATSGSFTNWSSEDALTLLDYFAISVTIIVVAVPEGLPLAVTLSLAFAMKKLMSDRALVRHLAACETMGSSTCICTDKTGTLTTNHMVVNKVWICDKVQERQEGSKESFELELSEEVQSTLLQGIFQNTGSEVVKDKDGNTQILGSPTERAILEFGLLLGGDFNTQRKEHKILKIEPFNSDKKKMSVLIALPGGGARAFCKGASEIVLKMCENVVDSNGESVPLTEERITSISDIIEGFASEALRTLCLVYKDLDEAPSGELPDGGYTMVAVVGIKDPVRPGVREAVQTCQAAGITVRMVTGDNISTAKAIAKECGIYTEGGLAIEGSEFRDLSPHEMRAIIPKIQVMARSLPLDKHTLVSNLRKIGEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKENADVIIMDDNFKTIVNVARWGRAVYINIQKFVQFQLTVNVVALIINFVSACITGSAPLTAVQLLWVNMIMDTLGALALATEPPNEGLMKRAPIARTASFITKTMWRNIAGQSVYQLIVLGILNFAGKSLLKLDGPDSTAVLNTVIFNSFVFCQVFNEINSREIEKINVFKGMFNSWVFTWVMTVTVVFQVIIVEFLGAFASTVPLSWQHWLLSILIGSLNMIVAVILKCVPVESRHHHDGYDLLPSGPSSSNSA
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into small vacuoles.
What are the official names of this protein?
Calcium-transporting ATPase 4, plasma membrane-type, Ca(2+)-ATPase isoform 4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast. Small vacuoles.
Protein: GCSH_SYNS3
Sequence: MAFDFPDQFRFADSHEYVRQEAELVRVGLSAYAVDQLGDIVFVDLPEVGDDLSRGTSFGTVESVKAVEEMYAPITGKVIQRNEAVLANPEELQNDPHGEGWLLVIRPSELAQIEELMDSATYSAKVAAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CD244_HUMAN
Sequence: MLGQVVTLILLLLLKVYQGKGCQGSADHVVSISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFIVKNLSLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFESLLPDKVEKPRLQGQGKILDRGRCQVALSCLVSRDGNVSYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNAHQEFRFWPFLVIIVILSALFLGTLACFCVWRRKRKEKQSETSPKEFLTIYEDVKDLKTRRNHEQEQTFPGGGSTIYSMIQSQSSAPTSQEPAYTLYSLIQPSRKSGSRKRNHSPSFNSTIYEVIGKSQPKAQNPARLSRKELENFDVYS
What is the function of this protein?
Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48.  SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.  Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2.  Acts as activating natural killer (NK) cell receptor (PubMed:10359122, PubMed:8376943, PubMed:11714776).  Activating function implicates association with SH2D1A and FYN (PubMed:15713798).  Downstreaming signaling involves predominantly VAV1, and, to a lesser degree, INPP5D/SHIP1 and CBL.  Signal attenuation in the absence of SH2D1A is proposed to be dependent on INPP5D and to a lesser extent PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:10934222, PubMed:15713798).  Stimulates NK cell cytotoxicity, production of IFN-gamma and granule exocytosis (PubMed:8376943, PubMed:11714776).  Optimal expansion and activation of NK cells seems to be dependent on the engagement of CD244 with CD48 expressed on neighboring NK cells (By similarity).  Acts as costimulator in NK activation by enhancing signals by other NK receptors such as NCR3 and NCR1 (PubMed:10741393).  At early stages of NK cell differentiation may function as an inhibitory receptor possibly ensuring the self-tolerance of developing NK cells (PubMed:11917118).  Involved in the regulation of CD8(+) T-cell proliferation; expression on activated T-cells and binding to CD488 provides costimulatory-like function for neighboring T-cells (By similarity).  Inhibits inflammatory responses in dendritic cells (DCs) (By similarity).
What are the official names of this protein?
Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NAIL, NK cell type I receptor protein 2B4, NKR2B4, h2B4, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane. Note=Receptor engagement results in a recruitment to lipid drafts essential for the subsequent tyrosine phosphorylation of the ITSMs.
Protein: NADR_SALTY
Sequence: MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPSAQKLEALHRFLGLEFPRRQKNIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGYDDTRDRGLFEDSAMSQQPTVSDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNGIKAFMAEKGIQPSWIYTSEEADAPQYLEHLGIETVLVDPERTFMNISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEMALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALIDEYRFDLVILLENNTPWVADGLRSLGSSVDRKAFQNLLVEMLKENNIEFVHVKEADYDGRFLRCVELVKEMMGEQG
What is the function of this protein?
This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase.  The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner.  As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes.  The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide.  The NMN adenylyltransferase activity catalyzes the transfer of the AMP moiety of ATP to nicotinamide ribonucleotide to form NAD(+).  The NMN adenylyltransferase domain also functions as the NAD and ATP sensor.
What are the official names of this protein?
Trifunctional NAD biosynthesis/regulator protein NadR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the bacterial RNK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm.
Protein: TFDD2_CUPPJ
Sequence: MIVDLPLRRIQQFARLGAKHQSSVLIRLHTKGGIVGIGESITPCGPWWSGDSVEAIQATINHYLAPLVVGEPALDASRIMAKLHGRVAGNAFAKAGIEMALLDAVGKIVDAPIHVLLGGRFRDRLSVAWPLATGDVNQEVDEAFRMLEAGKAGAFKLKMGALPLAQDLRRALAIAKELEGKASLRVDPNEAWDEPTTMRALAPLEAAGVEIIEQPVARWNLDAMARIHRQARSMLLIDEGVQSLHDASEVVKRAAAGLVSLKIMKTGGMRPARAMADIANAGGMHVYMGTFLETSIGTAANMQLAASIESLPYGGEVIGPLLIEEDLCEVPAVYKEHALWLPEGPGLGIRLDENQVRRFARASSQRIDRHSA
What are the official names of this protein?
Chloromuconate cycloisomerase, Muconate cycloisomerase II.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: GPI2_SCHPO
Sequence: MDEVCAAPAPKKMVAKSLVLNTFRKASVKEVVELKKPWKKVLWRKQDYPDNFIDESFLNGLQRNVNIQVTDFWSLVADSLPVSQHLSSVVIFASVFVSIYRNQLSCALVGFVSNVSAVAAFILWDFVLRKPCNNRTFPNYMGIVKSCILIVLTLAGLSPILMSLTKSTSPDSVWAIAVWLFLANVFFHEYTTETIRPHVRLHNSLSTNAALSASVVLASRLEKSINVFFFILFAVHWFALFPIFRKYIHVFSFYADMLMTLVLIISAYIALNAVASVVIAFVFLSLIFFISFICPIWFIKLQRFKNEIHGPWDIALPKLGPSKG
What is the function of this protein?
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit.
What is the protein family that this protein belongs to?
Belongs to the PIGC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.