PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_STAAE
Sequence: MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLITYDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIARMKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHVSTSRVADLIQHRKQRGVLTNDYVNVLELNIALDKMKD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ATPF_MYCSK
Sequence: MGDLSTTILAAEEGGGGNFLVPNGTFFFVLLIFLIVLGVIAKWVVPPISKVLQEREAMVTKTVEDNRKAADLFAAAQGDSQQVMAKARREASGIRDEARGEGRKILEDMRSRASAESAATLQKTNEELSRQGQQTAAELQSSIETLSATLASRVLGVDISSAAATSQGR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YHAM_ECO57
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLSVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What is the function of this protein?
Thought to be a D-serine dehydratase, however it does not complement a dsdA (D-serine dehydratase) mutant in strain CFT073, suggesting it may not have that function (PubMed:26727373).
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: SYT_FRATF
Sequence: MINIRFPDGSIREFEAGVNSLDVAKSISPSLAKATMAAYIDDQLKDAKDAINSNCELRLITVKDPEGLEILRHSCAHLLAHAVKELYPNTEVTIGPVVDNGFYYDFSFKESIGEADLPTIEKKMKELAKKSAPVSYRVVPKAEAIEFFKAQGENYKVEIIDSIADEQMKIYTQDNFSDLCRGPHIPNTSVLKAFKLTKLAGAYWRGNSDNEMLTRIYGTCWATKEDLEQYLNMLEEAEKRDHRKIGKVLDLFHFQEDSPGIAFWHDNGVRIWRQVEDYMRASNNKYGCSEIRTPLIADFSLWQKSGHASKYAENMFATKSENRDFAIRPMNCPTCVQVYNTKLHSYRDLPIRMAEFGIVHRNEPSGSLHGLLRVRSFTQDDGHIFCTPEQVEEEVILMVQQCFEVYKDFGFNDFAVKIALRPENRIGDDETWDKSEQILKNALDANNVSYELFPGEGAFYGPKIEFHLKDAIGRSWQCGTIQLDFSMPQRLGATYIDKNGEKQVSVMLHRAIVGSLERFIGMLIEHYAGNLPLWLAPVQVAVMGISNNQDDYCKEVFIMLEKNGIRAKLDLRNEKIGFKIREHTLLRVPYLVILGKNEQEQKIITIRKHSGEDLGQMSVDDFCAFLDKQIQAKE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_METCA
Sequence: MSGKTLYDKLWDDHVVHVDADGSCLIYIDRHLIHEVTSPQAFEGLRMAGRVPWRVDANLAVADHNVPTADRDRGIADPVSRLQVETLDKNCADFGITEFAMDDVRQGIVHVIGPEQGATLPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLVQRKAKNMLVRVQGKLAPGVTAKDLVLAVIGRIGTAGGTGYTIEFAGEAIRGLSMEGRMTVCNMAIEAGARAGLVAVDEVTLDYLEGRPFAPAGALWERAVEAWKDLHSDPDAVFDKVVEIDAASIKPQVTWGTSPEQVVPVDAEVPDPATEADPVRRESMERALQYMDLLPGTPIGAIRVDRVFIGSCTNARIEDLRAAAEVVRGHKRAASVKQALVVPGSGLVKRQAEQEGLDKVFLEAGFEWRDPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGYGGRTHLVSPAMAAAAAIHGHFVDITEGGRA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: YNCJ_ECO57
Sequence: MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEADSDELRAVAEESAEGLREHFYWQKSRKPEAGQR
What are the official names of this protein?
Uncharacterized protein YncJ.
Protein: P102C_LUPLU
Sequence: MGVFTFQDESTSTIAPAKLYKALVTDADIIIPKAVETIQSVEIVEGNGGPGTIKKLTFIEGGESKYVLHKIEAIDEANLGYNYSIVGGVGLPDTIEKISFETKLVEGANGGSIGKVTIKIETKGDAQPNEEEGKAAKARGDAFFKAIESYLSAHPDYN
What is the function of this protein?
Class II ribonuclease (RNase) (By similarity).  Binds to cytokinins (By similarity).  Interacts with melatonin (By similarity).
What are the official names of this protein?
Class 10 plant pathogenesis-related protein 2C, Llpr10.2c, Ypr-10.2c.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GRPE_POLNA
Sequence: MSENKQPEQNQDLTGEPSPEELEAAQAADEFDAMNAASEAQAQLAVLQAKNTELSDNYLRAKAEAENARRRAEDEISKARKFALESFAESLLPVLDSLEAGLNMKEATLEQLREGSQATLKQLKAALERNKVIEINPVAGSKFDPHQHQAISMVPAAQEANTVVAVLQKGYLIAERVLRPALVTVAAPQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM9_CANAW
Sequence: MLSRVARCSRTLNQVTRNGQSGLFSAVLRTSIRQNSTDSPASNNANEIYTKLSDTKDPQRNQFFQYTWGSWLTNDKSKKKQRETTFSIEGLTLFIDRINQLESKLAQPKSLEGAFVLANNKELLGSTKDKVIVRSIASIHEGKHHRVYKITLNTGKELVLRIPYKLDSDVAIASKLKSEVATTDFLKLKLGLNVPRVLAYGVDSNNEIKSPFILQEFISGELLMKKWHPLLPDSEETNKCLHEVIDPIAQFQNKILSVTFNKFGSLYFHDDVEGSLQNDVPYEGETDSALSNRWRIGPSVERQFTRNKNKLQQSIIDQYNGPWDASNPTAVLESVADIELENAKSKLSLINADAGANENDRALITKQIKTFENLKKISPQLINDKSKSIMNVEVLFKPRLYIPDLDPLNVIQHSDTENYFIDFEGSTIKPFILTSYPKFVAYQGAKIYNLEEDVPGYKEMEELEKQQYEFMYYKTRNERMWEFELNKYRHDLIAIASPHIKVLKSPYLQALDVKNGKDYLYVEGSIVQLQAMWEAYVANELVNSKDTKFPIEYTAEYLDQHQQELSDYQLETVSSPFSATGGWIPQDMFDTLKAQGILVETKDGNYKVETEKVLENPPAQPEEK
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECR_RHILW
Sequence: MAKRVTGPEIEKLIQLLAKVPGLGPRSARRAALHLIKKKDQLLGPLSNAMGEAYDKVKICSRCGNVDTVDPCTVCTDTQRDQSIIIVVEDVSDLWALERAGAMNAAYHVLGGTLSPLDGIGPDDLNIRGLIDRIGEGGIRELIIAVNATVEGQTTAHYITDQLQGLNVKITRLAHGVPVGGELDYLDEGTLAAALRARTVI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MSRA_STRPQ
Sequence: MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPEEISYKELVELYWVQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RL32_MYCAP
Sequence: MAIVPKRKTSKQRKHKRRTNDALPVQNLISCKNCSNMIQQHRVCEHCGFYKGKKVEGYKSLNLRAQ
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MTNB_PSEU2
Sequence: MSREQLSLEIIEAGRFLYGRGWSPATSSNYSARLSASEALLTVSGKHKGQLGPDDVLATDLAGNSLEPGKKPSAETLLHTQLYSCRPQVGAVLHTHSVNATVLSRLTTADHLVFEDYELQKAFSGVVTHESQVVVPIFDNDQDIARLAAKVQPWLDTHPECAGYLIRGHGLYTWGAKMSDALRQIEAFEFLFECELKMRAVMNR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: RSPO3_HUMAN
Sequence: MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPRLFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
What is the function of this protein?
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis.  Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway.  Acts as a ligand for frizzled FZD8 and LRP6.  May negatively regulate the TGF-beta pathway (PubMed:21727895, PubMed:21909076, PubMed:22615920).  Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells (By similarity) (PubMed:21727895, PubMed:21909076, PubMed:22615920).  Can also amplify Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3 (PubMed:29769720).
What are the official names of this protein?
R-spondin-3, Protein with TSP type-1 repeat, hPWTSR, Roof plate-specific spondin-3, hRspo3, Thrombospondin type-1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the R-spondin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR14_GUITH
Sequence: MAKKSMIERERKREELVSKYEKKRLELKSKLKKTAEYEEKLEVYKKIQEIPRNAFPSRLRNRCWVTGRSRGYYRDFGLSRHVLREMVHDCLLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DXS_MICAN
Sequence: MHLSEITHPNQLHGLSLRQLEDIARQIREKHLQTIAATGGHLGPGLGVVELTIALYQTLDLDRDKVLWDVGHQAYPHKLLTGRYNDFHTLRQKDGIAGYLKRCESKFDHFGAGHASTSISAGLGMALARDAKGEDFKVVSIIGDGALTGGMALEAINHAGHLPNTNIMVILNDNEMSISPNVGAISRYLNKVRLSEPVQFIADNLEEQFKNLPFFGDSLTPEMERVKEGMKRLAVPKVGAVIEELGFKYFGPIDGHNIPELIATFKQAHKVHGPVFVHVATVKGKGYEWAEKDQVGYHAQNPFNLATGKPIPSSKPKPPAYSKVFGHTLTKLAENDPRIIGITAAMATGTGLDKFQAKLPKQYIDVGIAEQHAVTLAGGLACEGMRPVVTIYSTFLQRAFDQIIHDICIQNLPVFFCMDRAGIVGADGPTHQGMYDIAYLRCIPNMTIMAPKDEAELQRMVVTGINHTSGPIAMRYPRGNGLGVPLMEEGWEALPIGKGEILRSGDDILLLGYGTMVNTSLQVAEILSEHGIEATVVNARFVKPLDTELIFPLAQRLGKVVTLEEGCLMGGFGSAVLEALQDANILVPVKRFGVPDKLVDHATPEESFADLGLTSPQIAQQVLAAFFSQKQTANVG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y123_RICCN
Sequence: MRILIILSIILCSLSIRADLEYVDNEIYNYNGGSNENGCVEVYDPYEKFNRKVFVFNSVLDYIILRPLAVGYKNITNDYVKARVNSFVSNVDTPLTAINYGLQLNYDKTMKSVWRFLINTTLGIGGLFDVAGKVGLPSDRQTFGSTLAHYGVAPGPYLVLPIIGSTNARDMTDSVITNYALNPLMYYTHNDFDLGVLAVSKINDRYVVLPFSDYVMKNSTDPYVAIRSALHRVREASVQYPENFKCPKPKN
What are the official names of this protein?
Uncharacterized protein RC0123.
What is the protein family that this protein belongs to?
Belongs to the MlaA family.
Protein: SEM6C_HUMAN
Sequence: MPRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLASQDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDLPPASASRSVPIPLLLASVAAAFALGASVSGLLVSCACRRAHRRRGKDIETPGLPRPLSLRSLARLHGGGPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPPELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGAEPPAPLTSRALPPEPAPALLGGPSPRPHECASPLRLDVPPEGRCASAPARPALSAPAPRLGVGGGRRLPFSGHRAPPALLTRVPSGGPSRYSGGPGKHLLYLGRPEGYRGRALKRVDVEKPQLSLKPPLVGPSSRQAVPNGGRFNF
What is the function of this protein?
Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro.  May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons.  May also be involved in the maintenance and remodeling of neuronal connections.
What are the official names of this protein?
Semaphorin-6C, Semaphorin-Y, Sema Y.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y2397_PHOPR
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRFVNYSTLHPKHDMQHLIKEVHKLIEESDDTKPLICGVGLGGYWAERIGFLCGIKQVIFNPNLNPSVNMEGRIDRPEEYIDIGTKCVADFREKNAGNCLCVLSTNDEVLDNQLTSDALSDFYKIIWDETQNHKFKKISQHLQAMKAFKE
What are the official names of this protein?
UPF0227 protein PBPRA2397.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: Y1173_ACIB3
Sequence: MLALISPAKTLDYETALPTDEFTQPRLLEHSAQLIDVCRKLSASEIASLMSVSEKIATLNADRFRDWKPEFDFSNARQAIYAFKGDVYTGLDAYHLKDKDIDFAQQHLRMLSGLYGLLRPLDLMMPYRLEMGTKLKNTRGHNLYEFWDDIITNQINEDLAAIKSELLVNLASDEYYKSVNEKKIKAEIVKPVFLDQKNGKYKVISFYAKKARGLMARFIIENQLNKAEDLKAFNTEGYYFDADNSSAKELVFKRDEQQA
What are the official names of this protein?
UPF0246 protein ABBFA_001173.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: ATPF_CUTAK
Sequence: MNILEMDLGPLAPEHPIEIIVGVILVLLLTWLIAKAVVPRFEKLYEERTETIQGGIERAERAQAEAKAALEKYQAQLASARDEAAQIRDDAKSQGAQIIAEMRANAQEEADRITERANAQIQAERDQAVREVRAEIGGLATTLASRIVGESLQDDQRVQATVDRFLSSLADEPSASNSRTVNRA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PANC_FRATO
Sequence: MIIADNIKQFHSIRNSLIKQQKIGFVPTMGALHNGHISLIKKAKSENDVVIVSIFVNPTQFNNPNDYQTYPNQLQQDIQILASLDVDVLFNPSEKDIYPDGNLLRIEPKLEIANILEGKSRPGHFSGTLTVVLKLLQITKPNNLYLGEKDYQQVMLIKQLVKDFFINTKIIVCPTQRQPSGLPLSSRNKNLTSTDIEIANKIYEILRQDDFSNLEELTNKINSTGAKLQYIQKLNNRIFLAFYIGKVRLIDNFLKETGPSC
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBIS2_ARATH
Sequence: MESQTKFDYESLAFTKLSHSQWTDYFLSVPIDDSELDAITREIDIIKPEVRKLLSSKGDDETSKRKVLLIQSLLSLGLAFHFENEIKDILEDAFRRIDDITGDENDLSTISIMFRVFRTYGHNLPSSVFKRFTGDDGKFERSLTEDAKGILSLYEAAHLGTTTDYILDEALEFTSSHLKSLLVGGMCRPHILRLIRNTLYLPQRWNMEAVIAREYISFYEQEEDHDKMLLRLAKLNFKLLQLHYIKELKTFIKWWMELGLTSKWPSQFRERIVEAWLAGLMMYFEPQFSGGRVIAAKFNYLLTILDDACDHYFSIPELTRLVDCVERWNHDGIHTLEDISRIIFKLALDVFDDIGRGVRSKGCSYYLKEMLEELKILVRANLDLVKWARGNQLPSFEEHVEVGGIALTTYATLMYSFVGMGEAVGKEAYEWVRSRPRLIKSLAAKGRLMDDITDFESDMSNGFAANAINYYMKQFVVTKEEAILECQKMVVDINKIVNEELLKTTTVPRRVLKQALNFGRLLEVLYTKSDDIYNCSEGKLKEYIVTLLIDPIHL
What is the function of this protein?
Involved in sesquiterpene (C15) biosynthesis.  The major product is (Z)-gamma-bisabolene with minor amounts of (E)-nerolidol and alpha-bisabolol.
What are the official names of this protein?
(Z)-gamma-bisabolene synthase 2, Terpenoid synthase 13, AtTPS13.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_DECAR
Sequence: MIETDKLTPAVDRTNLDRVVAPQTKSAQEEALERALRPKRLADYTGQVKIREQLEIFIQAARNRSESLDHVLLFGPPGLGKTTLAHIVAAEMGVNLRQTSGPVLERAGDLAAILTNLEPHDVLFIDEIHRLSPVVEEILYPALEDFQIDIMIGEGPAARSVKLDLPPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTAEELKSIVSRSASLLNAPIDPEGSFEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITRQVADAALHMLDVDPAGLDIMDRKLLSAIIDKFGGGPVGVDNIAAAIGEARDTIEDVLEPYLIQQGYLQRTLRGRIATPAIYRHLGLAEPASAVVRDLLAEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: UDGA_PYRAE
Sequence: MDLQKLHELIKNCDKCPLHKYRKNAVPGEGEMKLGVMIVGEAPGASEDEAGRPFVGAAGQLLTEALSRLGVRRGDVFITNVVKCRPPNNRTPNREEVEACLPYLIQQIGILKPRRIIALGLISAKALMELMGRRAEKLGDVKGKCYQGRIAGVQVELCITYHPAAVLRKPALRGEFQKDLAMFFGGGLDRFLDPSK
What is the function of this protein?
Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP.  Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.
What are the official names of this protein?
Type-4 uracil-DNA glycosylase, Pa-UDG, Pa-UDGa.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
Protein: PROA_XANOR
Sequence: MTIKTLALQCRDAAQVVSQLSSQAKCALLQAMAAALEADAGTILAANARDLEAARAKGTASAMLDRLALDDKRLAGIAAALREVALLPDPVGRITREDVRPNGIRVQKVRVPLGVIAMIYEARPNVTADAAALCIKAGNGVILRGGSEAIHSNTAIARALQRALREANVPEAALTLVEDLRRETMLELLQLNDIVDLAIPRGGEGLIRFVAEHARVPVIKHYKGVCHLFVDASAEMELALRLLIDGKATRPSACNSLETLLVHADIAERFLPLAAQALRERKVELRGDAATRAVLPEIAPASDDDYAAEFLDLILAMRVVADLDTALAHIRQYGSDHTEVIATQDPDNAERFVQSLRSAVVMVNASSRFSDGGELGLGAEIGISTTRLHSYGPMGLEALTVERFVVRGEGQVRH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRP10_SCHPO
Sequence: MSKKIVNPPRLQGLSRLRVRPKREKNTIPCGQEMAALLGCWQNHGGQTDTAQCANLVAALENCMKTTHRKTKSENTINYHLARLGKLL
What is the function of this protein?
Involved in mitochondrial genome encoded proteins translation.
What are the official names of this protein?
37S ribosomal protein mrp10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS37 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CLPP_PSEPK
Sequence: MSRNSYIQQSSDIQAAGGLVPMVIEQSARGERAYDIYSRLLKERVIFLVGPVEDYMANLVVAQLLFLEAENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTICIGQACSMGAFLLAAGAKGKRHCLPNSRVMIHQPLGGFQGQATDIEIHAQEILNIKARLNELLAYHTGQDLETIKRDTERDNFMSASRAAEYGLIDSVYDKRQLAS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REG7_PYRFU
Sequence: MIDERDKIILEILEKDARTPFTEIAKKLGISETAVRKRVKALEEKGIIEGYTIKINPKKLGYSLVTITGVDTKPEKLFEVAEKLKEYDFVKELYLSSGDHMIMAVIWAKDGEDLAEIISNKIGKIEGVTKVCPAIILEKLK
What is the function of this protein?
DNA-binding protein that negatively regulates its own transcription (PubMed:10973967, PubMed:11809882).  Interferes with RNA polymerase (RNAP) recruitment by inhibiting the association of RNAP with the TBP-TFB promoter complex (PubMed:11809882).  Binds to a 46-base pair sequence that overlaps the transcriptional start site of its own promoter (PubMed:10973967).
What are the official names of this protein?
HTH-type transcriptional regulator LrpA.