PharMolix/UniProtQA huggingface dataset:
Protein: REM4_ARATH
Sequence: MADPLIPSPTNKAFFIIDLSGQKSNPIIPTEFIWNHFNGKIQSTNMKLTSDASDRNWDVKLDGARFAGGWKDFSVSHSVRDDDLLSFRHDGGMVFHVSPFGRSFSQIQLISSSTSDDDDDERTVFDDDEDDDVGDDDDNSISEDDFCSKKISSKKRARKETESSSDKSYLVAHVTPSSLLRDNMCVLSKFARSNGLDRRECEIDLRDEHEKSWTLLLRHNKKTGQAFMRGGWRSFCRNNGIKAGSICRFKLVQSGIKPVLQLCPNASSIPEGNSSKARKKRNVSEIEGDEIESENCSETIPLNQNKILTFDLKPYVFRSCQFFLPASFARENGIVEAGEVTVLNKDGIEWKSHLVNIKGRDQFYNRGCQDFFVANGVKNVGDPFTLEVIRGGPSPILKICSKVKQAASSDGHKTADRKPRMTDQAPLAEEQTDNRVEKRAQVTEEGGPSRSTRADPGNLQQKQPCSISDHVKKVKQSIVDTLTDVRRFQSELKVKEQNLEASLQEIDALGMI
What are the official names of this protein?
Putative B3 domain-containing protein REM4, Protein REPRODUCTIVE MERISTEM 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: CPT1A_HORSE
Sequence: MAEAHQAVAFQFTVTPDGIDLRLSHEALKQICLSGLHSWKKKFIRFKNGVITGVYPASPSSWLIVVVGVMSTMYAKIDPSLGIIAKINRTLDTTGYMSSQTKNIVSGVLFGTGLWVALIITMRYSLKVLLSYHGWMFAEHGKMSRATRIWMCMVKIFSGRKPMLYSFQTSLPRLPVPAVKDTVNRYLESVRPLMKDEDFKRMTALAQDFAVNLGPRLQWYLKLKSWWATNYVSDWWEEYVYLRGRGPLMVNSNYYAMDLLYVIPTHLQAATAGNGIHAILLYRHKLDREEIKPILFLGSTVPLCSAQWERMFNTCRIPGEETDTIQHLRDSKHIVVFHKGRYFKVWLYHDGRLLKPREIEQHIQRILDDPSEPHAGEAKLAALTAGERVPWAKCRQAYFGRGKNKQSLDAVEKAAFFVTLDETEQGYREEDPDASMDSYAKSLLHGRCSDRWFDKSFTFIVFKNGKMGMNAEHSWADAPVVGHLWEYVMSTDCFQLGYAEDGHCKGDTNPNIPYPTRLQWDIPEECQDVIETSLNTANILASDVDFHSFPFHAFGKGLIKKCRTSPDAFVQLALQLAHYKDMGKFCLTYEASMTRLFREGRTETVRSCSSESCNFVLAMVDPTQTVKQKLRLFKIASEKHQHLYRLAMTGSGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQTPQQQVELFDLERNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSSPETDSHRFGKHLKQAMNDIMALFGFSSNSRKEFH
What is the function of this protein?
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion (By similarity).  Plays an important role in hepatic triglyceride metabolism (By similarity).
What are the official names of this protein?
Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: TRPF_PARL1
Sequence: MSVQVKICGLSTPETIEASVSAGADYLGFVFFSRSPRHLSYELAARLSGYVPASVPKVALTVDADDAMLDAVVEALRPDILQLHGDETPQRLVEIKARYGLTLMKAICVAQPEDPLTAAIYRDSADLLLFDAKPPKSMAGALPGGNGLVFDWSLIAGHRPETPWMLSGGLNAENVAEAVRITGAEAVDVSSGIEEGPGRKTPELIEAFIRAAKRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: GCS2_POLNA
Sequence: MSLEPFQKSSALSLGVELEMQLVNTHDYDLAPYAEDMLRLMSKIALPGAVVPEMTSSMIEVSTGICHSSAEVLGQLTQIRDALVKSADKLNIAVVGGGTHPFQQWHERRIYDKPRFRELSELYGYLSKQFTIFGQHVHIGCPDADTALLTLHRMSRYIPHFIALSASSPYVQGQDTAFDSARLNSVFAFPLSGRAPFALTWDEFTVYFNKMAHTGVVKSMKDFYWDIRPKPEFGTIEIRVFDTPLTIERATALAGYVQSLGSWFMNDQPFMPTEDDYLVYTYNRFQACRFGLDAVYVDPATGGHMPLREHILMTMAQIERHAHRLDASASIHLLRTSVERNDNDARWLRERQGEERLLAEVIRQAADRFRGGVDHEPGGFS
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: RR14_OENBI
Sequence: MARKGLIQREKKREKLEQKYRLIRRSSKKEISTAPSLSEKWKIHGKLQSSPRNSAPTRLHRRCFSTGRPRANYRDFRLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL40_METS5
Sequence: MPLTDQAKIQIVQERVFIKKVCRNCGALNSIRATKCRRCHSTNLRPKKKELPTKRA
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: PLSY_COXBR
Sequence: MAFIISIIIAYLLGSLSFAVIVAKLMKLPDPRTTGSGNAGATNMLRVGGRQAAFYVLLGDAAKGLIAVLIARFLNVQGVSLAFVGLVAVLGHLFPVYFKFRGGKGVATMMGVLLGLSFWIGLFVIATWVIVVSIFRYSSVAALVSAVAAPIYTIIAGRTDYLFPVLIIAILIIWKHWENFQRLRKGTEDKVKL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FKBP6_BOMMO
Sequence: MEFQIDVDFQNRKTEMFINGDDDLFPEMGDEDDSDGEDTLRNIEETTKKMMLASPDYLSFEELGANMIDCMSTGDVKMLIIEEGKGPLVPVDSEVTIHYAAYWEKAVIPFDSTLTMNMGAPKRLRLGTGKIIPGLEIGLTMVKGPQARLNLLVQPAAAWGPRGVPPRIRPEPALFVIVLYDVKDNYAATRFNDLPMAEQTKYEVTLRTVNALRADAKELYKKKKYVKAIKNYQQAISVLRLSRPGTADEELDIKNNKVNAYLNLAVCYYKTNKPKHVLNMCECLDRLIDTEKHCKALYYYGKAHEMLGKTEMAIKYYKKALKLEPKNKEIGKILADLDTKTKDFAVNEKAMWLKAFNVEVPATNAVYDVDATFQSDVLDMCQSLAGRSEFAKFDLPVGLTKNEVDCIKGIVSDFGCLSVDVSGEGRNKKVCIVKKIV
What is the function of this protein?
Co-chaperone required during oogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Acts as a co-chaperone via its interaction with Hsp83/HSP90 and is required for the biogenesis of all three piRNA major populations (By similarity).
What are the official names of this protein?
Inactive peptidyl-prolyl cis-trans isomerase shutdown.
What is the protein family that this protein belongs to?
Belongs to the FKBP6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_METLZ
Sequence: MVEVQKEQVYVIPLRDVKRVPCYKRANAAIKDIRGYLEHHMKSDDVKLDKSINELVWARGSQKPPRRIRVRAMKFEDGQVQAELAEE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: OBG_BACFR
Sequence: MAESNFVDYVKIYCRSGKGGRGSTHMRREKYTPNGGPDGGDGGRGGHVILRGNRNYWTLLHLRYDRHAMAGHGESGSKNRSFGKDGADKIIEVPCGTVVYNAETGEYVCDVTEHGQEVILLKGGRGGLGNWHFKTATRQAPRFAQPGEPMQEMTVILELKLLADVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGQSFVMADIPGIIEGASEGKGLGLRFLRHIERNSLLLFMIPADSDDIRKDYEVLLNELKTFNPEMLDKQRVLAITKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWTELNKESNKIEAIVHRPKDVSRLQQELKDMGEDEELDYEYEDDGDEDDLDYEYEEEDWEDK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_PSEU2
Sequence: MAFTDRLLDAWYKGHPALALLRPLEGLYRRVVERKRARFLAGEGDIYRAPVPVIVVGNITVGGTGKTPLILWMIEHCRRRGLRVGVVSRGYGAKPPSLPWRVLPDQSASEAGDEPLLIVQRCGVPLMIDPDRSRAVQALLAAEPLDLILSDDGLQHYRLARDLELVLIDAARGLGNRRCLPAGPLREPVERLSSVDALLYNGAMADRGDGYAFRLKPSALINLRSGERQPVDYFPAGQALHAVAGIGNPRRFFNTLEGLHWRPVPHAFADHAVYSAEALTFTPALPLVMTEKDAVKCRAFAADDWWYLAVDAVPSDAFVGWFDQQLLRLSP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: VF84L_ASFM2
Sequence: MMLFITVYDINRKQKKRYGLHG
What are the official names of this protein?
Uncharacterized protein C84L, pC84L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C84L family.
Protein: HEM3_STAAR
Sequence: MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKKVSNKLKEQGAYEIIKRLNEQH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CH60_SOLM1
Sequence: MAAKEILFDSKAREKLKRGVDKLANAVKVTLGPKGRNVVIEKSFGSPIITKDGVTVAKEIELEDKFENMGAQMVKEVASKTSDIAGDGTTTATILAQAIFTEGVKLVAAGRNPMAIKRGIDKAVASVVAELETLAKPTRDQKEIAQVGTISANSDATIGNIIAEAMNKVGKEGVITVEEAKGMETTLDVVEGMQFDRGYLSPYFITDPERMVCELDEPLILINEKKITAMKDLLPVLEQVAKMSRPLLIVAEDIEGEALATLVVNKLRGTLQVCAVKAPGFGDRRKAMLEDIATLTGGQCVSEDLGIKLENMTLADLGKAKRVIVDKENSTIVDGAGDGDKIKARVKQIRAQIEETTSSYDKEKLQERLAKIVGGVAVINVGAATETEMKEKKARVEDALNATRAAVEEGIVPGGGVALVRCVKSLTGIKAVDDDEQSGIEIVRRAIEEPLRQISGNAGFEGSIVVAKVRDGKDGFGFNAATGEYEDLIKAGVIDPKKVTRIALQNSSSVAGLLLTTEAAIAEKPEPKKDMPPMPGGGMGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNKD_HUMAN
Sequence: MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPELEYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK
What is the function of this protein?
Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
What are the official names of this protein?
Probable hydrolase PNKD, Myofibrillogenesis regulator 1, MR-1, Paroxysmal nonkinesiogenic dyskinesia protein, Trans-activated by hepatitis C virus core protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Mitochondrion.
Protein: WDR13_PANTR
Sequence: MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQLLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSAAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLRVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDSAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGTLQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQK
What are the official names of this protein?
WD repeat-containing protein 13.
What are the subcellular locations of this protein?
Nucleus.
Protein: WNT3A_MELGA
Sequence: SGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEMVVEKHRESRGWVETLRPKYNFFKAPTEKDLVYYENSPNFCEPNPETGSFGTRDRICNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family.  Required for normal embryonic mesoderm development and formation of caudal somites.  Required for normal morphogenesis of the developing neural tube.
What are the official names of this protein?
Protein Wnt-3a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: Y5296_TRIV2
Sequence: MQTLVFFLIAALGEIFGCYTFWVWLRLGKSILWIVPGVLALIVFAFALTKVNASNAGRVYAAYGGVYILSSVVWLWLAEGVKPDKWDLLGVTICLLGTVVILFSHYR
What are the official names of this protein?
UPF0060 membrane protein Ava_B0196.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DU4L6_HUMAN
Sequence: MALPTPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDRDPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPLLETEAPGELEASEEAASLEAPLSEEEYRALLEEL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Double homeobox protein 4-like protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAER1_XENLA
Sequence: MFKGILLCVLFAVLSANPLSQPEGFADEERDVRGLASFLGKALKAGLKIGAHLLGGAPQQREANDERRFADDDDDVNERDVRGFASFLGKALKAALKIGANMLGGTPQQREANDERRFADDEDDVNERDVRGFGSFLGKALKAALKIGANALGGSPQQREANDERRFADGQQDYTGWMDFGRRNGEDD
What is the function of this protein?
The pharmacological activities of caerulein are quite similar to the physiological activities of gastrin and related peptides.
What are the official names of this protein?
Preprocaerulein type-1, Preprocaerulein type I.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_THEP1
Sequence: MATVLIVGKPNVGKSTLFNKLVRKKKAIVEDEEGVTRDPVQDTVEWYGKTFKLVDTCGVFDNPQDIISQKMKEVTLNMIREADLVLFVVDGKKGITKEDESLADFLRKSNVDTILVANKTENLREFEREVKPELYGLGFGEPIPVSAEHNVNLDVLVETIIRKLEEKGLDLESKPEITDAIKVAIVGRPNVGKSTLFNAILNKERALVSPIPGTTRDPVDEEVFIDGRKYVFVDTAGLRRKSRVEPRTVEKYSNYRVVDSIEKADVVVIVLDATQGITRQDQRIAGLVERRGRASVVVFNKWDLVEHREKRYDEFTKLFREKFYFVDYSPLIFISADKGWNIDKVIDAINLAYASYTTKVPSSAINSALQKVLAFTNLPRGLKIFFGLQVDIKPPTFLFFVNSIEKIKNPQKVFLRKLIRDYVFPFEGSPIFLKFKRSR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RM04_COCIM
Sequence: MASRSVISFLYQQGGLSLAELPPAFLAPALYSTKASFNSQRSQFSTSSSPAARDRSRFRGVSAIHRTGPKQPLPVSKYPLPKPASPEQQEKRPANPDHGLWGFFGPNKQAIPTPEEEYAHGRAWTIQELRQKSWDDLHCLWWVTVRERNRIATSNYERKRLAAGYGDFEADNRDKTVRATQHAIKHVLRERWYAWNEARELYNGGYRPSPDEVLEEETETAMPTEVMPEELDSSTKSETTTSKNI
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NSG1_MACFA
Sequence: MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA
What is the function of this protein?
Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway.  Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity).  Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity).  In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (By similarity).
What are the official names of this protein?
Neuronal vesicle trafficking-associated protein 1, Neuron-enriched endosomal protein of 21 kDa, Neuron-specific protein family member 1.
What is the protein family that this protein belongs to?
Belongs to the NSG family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Cell projection, dendrite. Early endosome membrane. Late endosome membrane. Lysosome lumen. Recycling endosome membrane. Cytoplasmic vesicle membrane. Golgi apparatus, Golgi stack membrane. Endosome, multivesicular body membrane. Endoplasmic reticulum membrane. Note=Endocytosed from the cell surface, thus enters into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Endoplasmic reticulum targeting is essential for apoptosis (By similarity). Found in both stationary and motile endosomes. A previous study supports a type I membrane protein topology (By similarity).
Protein: IXTPA_BRASB
Sequence: MSSSHRKLSGRIVIATHNPGKLAEMRELLAPYGVEAVSAGELSLGEPDETGETFQANARIKAVAAADAAQLPAFADDSGIVVHALDGAPGIYSARWAGPDKDFTAAMTRIERLLQERGATGPDKRGAHFVSALCVAWPDGHVEEVEARVDGTLVWPPRGSAGFGYDPMFLPEGHDRTFGEMTSLEKHGLPPLGLGLSHRARAFVKLAEICLDQR
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: AMIE_HELPJ
Sequence: MRHGDISSSPDTVGVAVVNYKMPRLHTKNEVLENCRNIAKVIGGVKQGLPGLDLIIFPEYSTHGIMYDRQEMFDTAASVPGEETAILAEACKKNKVWGVFSLTGEKHEQAKKNPYNTLILVNDKGEIVQKYRKILPWCPIECWYPGDKTYVVDGPKGLKVSLIICDDGNYPEIWRDCAMRGAELIVRCQGYMYPAKEQQIAIVKAMAWANQCYVAVANATGFDGVYSYFGHSSIIGFDGHTLGECGEEENGLQYAQLSVQQIRDARKYDQSQNQLFKLLHRGYSGVFASGDGDKGVAECPFEFYKTWVNDPKKAQENVEKFTRPSVGVAACPVGDLPTK
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: SSTT_DESHY
Sequence: MKELLRKWNNISLVKRILMGLIIGIMLALWIPDIAAPVAILGNLFVGALKAVAPVLVLILVMGAIANHKSGQQTNMKSILILYLLGTFLAGVTAVIASFMFPVSIALAAGAEDITAPGGITEVLLSLLMNVVDNPVKALMNANYIGILSWAILLGLALRTAGESTKQLIGDFADAVSKVVKWVINLAPLGILGLVFDSIATSGLEVLLGYGKLLLLLVGCMVFVALIINPLIVYLKIRKNPYPLVFRCLRESGITAFFTRSSAANIPVNLTLCEKLGLDRNTYSISIPLGATINMAGAAVTIAVLTLAAVHTLGITVDIPTAIILSVLSAIAACGASGVAGGSLLLIPLACSLFGISNDIAMQVVGVGFIIGVVQDSCETALNSSTDVLFTAAAEYGEWRKEGKAF
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G3P_STRP6
Sequence: MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAKKEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPMAKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTEDPIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_LEIXX
Sequence: MADHKLPRKEVAPRPDQTELRVGRLTKAHGLKGAIKLELFTDEPGKRFVPGAVFTLQVPTASKWHGKTLALRELRWYNGHPVGFFDGVDDRTEAESLVKAILWVNQDVRELPDEEDAWYDNQLVGLSAHRDGAVVGAIVRVDHLPGQDLLAIKTPGGEVLVPFVKAIVPEVDLAARTVTLTPPPGLFEDLPDDAPAAGDESEPVSPPVTAEETPGGE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRG_YERPG
Sequence: MHVTLVEINVKEDKVDQFIEVFRANHLGSIREAGNLRFDVLRDEHIPTRFYIYEAYTDEAAVAIHKTTPHYLQCVEQLAPLMTGPRKKTVFIGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.