PharMolix/UniProtQA huggingface dataset:
Protein: MID51_HUMAN
Sequence: MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSPTRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEVQYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT
What is the function of this protein?
Mitochondrial outer membrane protein which regulates mitochondrial fission.  Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins.  Regulates DNM1L GTPase activity and DNM1L oligomerization.  Binds ADP and can also bind GDP, although with lower affinity.  Does not bind CDP, UDP, ATP, AMP or GTP.  Inhibits DNM1L GTPase activity in the absence of bound ADP.  Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP.  Does not require ADP for its function in recruiting DNM1L.
What are the official names of this protein?
Mitochondrial dynamics protein MIEF1, Mitochondrial dynamics protein of 51 kDa, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, SMCR7-like protein.
What is the protein family that this protein belongs to?
Belongs to the SMCR7 family.
Protein: Y100_THISH
Sequence: MPITDWPADERPREKLLSRGAAALSDAELLAIFLRTGVAGKTAVDLARELLSRFGGLRPLLQADLVSFSSARGLGSAKYAQLQAVLEMGRRHLSESLARGDALTSPDDTRRFLAARLRDYPFEVFACLFLDNRHRVIAFEELFRGTIDGASVHPREVVRRALAHNAAALILAHNHPSGVAEPSRSDEAITRRLRDALALVDIRVLDHVVVGDSLVSFAERGLL
What are the official names of this protein?
UPF0758 protein Tgr7_0100.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: TYRO3_XENLA
Sequence: MVYPGPPGLIAGLLLAALSLSCVDGAKALGFVGHGYNLTVSQGHEAKLNCSLQGIEEPEIQWLKDGVPVQSADQMYIPVDEDHWISFLSLKNVERPDAGKYWCEAEHSGRKSVSDAIWIMVEGVPYFTLEPKDLSVTPNSPFNMTCAAVGPPEPLVIIWWVGDSPLGKSESSPSVLQMSGIHERTAFSCEAHNAKGVSSSRTAIVEVKGLPYPPFNVTISKVTGSTATVTWFPGFNSFSLIKSCTIQVQSLHGNREMYSRLISAPPFAVLLDELQPLTNHSVRVQCTNEMGASPFTEWRTFHTKETVPQLLPQNVHMTKTETSLLLDWEEVEPDREGYNILGFKVQWEQENATQGELFVQENQANLTKWNPEKDLTIRICIANAAGCGPWSEFLLAGSKEEAGKQRHPHTRMSWVPMVLGILTALVTVVAMTLIFLRKGRKETRFGNMLGSMLGRGGPVIQFTAARSFNRRGPEMMEATLDSIGISEELKSKLKDVLIQQQQFTLGRTLGKGEFGSVREAQLKMEDDTMQKVAVKMLKAEIFCSSDIEEFLREAAFMKEFDHPNVCKLIGVSLRSRTKGRLPVPMVILPFMKHGDLHTFLLMSRIGEEPITLPVQTLVRFMIDICSGMEYLSSKNFIHRDLATRNCMLNEDMTVCVADFGLSKKIYSGDYYRQGCASKLPVKWLALESLADNVYTVHSDVWAFGVTLWEIATLGQTPYAGVENSEIYSYLIAGNRLKQPLDCLDELYEMMCQCWITEPKRRPSFVDLKQRLEAIWGRLSILSASQDQLYVNLGETCGAAAAVSGLHSAFCSEEDYCAGPSQTCGTSAITSDYRYIVNPGCLREGNEWSSSAQNGEARGLLHEEEEEEEEEMQEEQVVITL
What is the function of this protein?
May be involved in cell adhesion processes, particularly in the central nervous system.
What are the official names of this protein?
Tyrosine-protein kinase receptor TYRO3, Xenopus kinase of Sky family, Xksy.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: C2D1B_RAT
Sequence: MPGPRPRKGPKTSGQGAETAKQLGLFVEFNPEDMLLGMDETEDDGDLEAELLALTGETGSTSRKPAPKGRAPLPMAHIEKLAADCMRDVEEEGEEEEGLEDDADLLTELQEVLGVDEETGLVDDSEETSPDLSEEKTRDNTEQPVAPAAFQQALPAAVAQAGGPRGLQALLEERIQNYREAAASAKEAGEAAKARRCERGLKTLESQLATVRKGGKICEDEIPPPVALGKRPPAHQERPSKDSEIDSAGSCAMDPGDLSQPESSLPAVAALPDSDPDPQALLLARQREYKAAALSAKRAGDLDRARELMRIGKRFGTVLEALEKGQPVDLSGMPPAPEDLKALPQASEASAATQVLSPAVEQMQPVMSSDLPATPAAPAEPKTVLDALQQRLNRYREAGIQARASGDERKARMHDRIAKQYQDAIRAHQAGRKVDFAELPVPPGFPPIPGLEPRKDTEEDSVTATLAAAQKLASEDTALVDEDEERDTPAQAPLAKKPAQPLVPSSHLLNEPKASSSKESLSPSVREQVTLLEARKLQYQRAALQAKRRQDLEQAKSHLRVAKSLEAQIIQARAGQPIDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKILLEQHEKCLLFSKQFMHQGNVAETTRFEKLAEDRKKQLEILQLAQAQGLDPPSHHFELKTLQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFEQVFKLNINRNHRGFRRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLEKECEIREIMEVLDGRKPTGGKLEVKVRLREPLSSQDVQMVTENWLVLEPRGL
What is the function of this protein?
Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.
What are the official names of this protein?
Coiled-coil and C2 domain-containing protein 1B, Five prime repressor element under dual repression-binding protein 2, FRE under dual repression-binding protein 2, Freud-2.
What is the protein family that this protein belongs to?
Belongs to the CC2D1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCDGK_HUMAN
Sequence: MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKWKQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-C3, PCDH-gamma-C3, Protocadherin-2, Protocadherin-43, PC-43.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TEFF1_XENLA
Sequence: MDGLHPASWMLLLGSLAFWSASSLLLFSLALPGARASNQLLSECHNGKGKGINCSELTVRESEVRVCDESSCKYGGVCKEEGDVLKCICQFQCQTNYAPVCGSNGDTYQNECFLRRSACKQQKDITVVARGPCFSDIASGSGEGEYEGSGGEVHKKHSKCGVCKFGAECDEDAGDVGCVCNIDCSGHNFNPVCATDGSSYSNPCLVREASCLRQEQIDVKHIRSCIETDETSIMGKKDEGLQNRPEVKDSTDQREGDFMGNYIPCSENYNGYCVHGKCELSYSSQKASCRCDSGYTGQYCDKTDFNILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFSSDTSSRMV
What is the function of this protein?
Inhibits nodal/nr-1 and bmp signaling during neural patterning through interaction with cripto.
What are the official names of this protein?
Tomoregulin-1, TR-1, Transmembrane protein with EGF-like and one follistatin-like domain, X7365.
What is the protein family that this protein belongs to?
Belongs to the tomoregulin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GLAK2_ARATH
Sequence: MDPNPKPAISGKDNGVFEHRSFARIGFLGNPSDVYFGRTISFTIGNFWAWAKLEPSDHLLIKPHPFHDLVQFDSLDNLVYRLENDGYYGGVRLLMAICKVFRNYCKENGIQLHDKNFTLSYDTNIPRQTGLSGSSAIVSAALSCLLDFYNVRQSIRIEVRPNLILNAEKELGIVAGLQDRVAQVYGGGLVHMDFSKEHMDKVGYGIYTIMDINLLPPLHLIYAENPSDSGKVHSTVRRRWLDGDEFIISSMAEIAKLAEEGRTALLKKDYSNLKELMNRNFDLRRSMFGDECLGAMNIEMVEVARKIGAAAKFTGSGGAVVVFCPEGPSQVKLLEEECRKSGFIVEPVKLVPTRLSSSDIKTLSKT
What is the function of this protein?
Sugar-1-kinase with a strict substrate specificity for D-glucuronic acid and ATP.  Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.  May be also involved in a salvage pathway for glucuronic acid (By similarity).
What are the official names of this protein?
Probable glucuronokinase 2.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family.
Protein: FRDC_SALDC
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPTVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YJNK_SCHPO
Sequence: MSAAGGIVYVIVGGNRGIGLSLVKELSNKEGVTVFASARGPGSASELKDWSKTHSNVHIIKLDVTSLRSAKDAAMQVEKVVKCIDVLWVNSGISKSFQPVLKTSDELWMSHYQTNVLGPIHVYQAFYHLLKEGKLKNIVFTSSMAACMGGVRPNTYSAYGQSKAALNYTMKEISFELEKDGFVVVSIHPGVVNTDMFVNAMQKLASKYPEMVESIKSNAISPEQSASSMLKIVDNLKTEDNGMFYNLDGTKLPF
What are the official names of this protein?
Uncharacterized oxidoreductase C24B10.20.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUA4L_HUMAN
Sequence: MAGASLGARFYRQIKRHPGIIPMIGLICLGMGSAALYLLRLALRSPDVCWDRKNNPEPWNRLSPNDQYKFLAVSTDYKKLKKDRPDF
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2, NADH-ubiquinone oxidoreductase MLRQ subunit homolog, NUOMS.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA4 subunit family.
Protein: IDH_SYNY3
Sequence: MYEKLQPPSVGSKITFVAGKPVVPNDPIIPYIRGDGTGVDIWPATELVINAAIAKAYGGREEINWFKVYAGDEACELYGTYQIFPEDTLTAIKEYGVAIKGPLTTPVGGGIRSLNVALRQIFDLYTCVRPCRYYPGTPSPHKTPEKLDIIVYRENTEDIYLGIEWAEGTEGAKKLIAYLNDELIPTTPALGKKQIRLDSGIGIKPISKTGSQRLVRRAILHAKRLPKAKQMVTLVHKGNIMKFTEGPFRDWGYELATTEFRAECVTERESWICGNKESNPDLTIEANAHMIDPGYDTLTEEKQAVIKQEVEQVLNSIWESHGNGQWKEKVMVNDRIADSIFQQIQTRPDEYSILATMNLNGDYLSDAAAAVVGGLGMGPGANIGDSAAIFEATHGTAPKHAGLDRINPGSVILSGVMMLEFMGWQEAADLIKKGIGAAIANREVTYDLARLMEPKVDKPLKCSEFAQAIVSHFDD
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORW_AERS4
Sequence: MKAATLSEAGVSREILVIGSGFAAQQLVKSLRKLDAEQPIRLITADSGDEYNKPDLSHVVSRGCTAAAMTRLSGSDFAEQQRIALVPHCPVLGIDPARRIVMTVQGEFAYGQLVLATGASAARPDLPGSEQLVTLNSQQEYAAAEGPIQQARRILVLGAGLIGCELAMDMASDGREVTLVDLADSPLSALLPAVLSQPLQQALRSQGVSLQFGLGIARIDAQPGDGWRVTLTDGRTSEQDLVIAAIGLKPNLVLAQAAGLAVERGILVDDSLQTSAPHIFALGDCAQWRGQLLPFLQPIVLGANALARTLLGTPTPLTLPPMLVKVKTPRYPLQLAGRTKGEDLAWQCRWNSHGLVAEARAEDGELCGFVVGGDQMSAAFPLLRQLPR
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_GAHVM
Sequence: MNVHESHPRRDRDLENITLEALTVPWRLQFRVDEALYAVNPNGWTCYIEERDQRCLRVTNNCVISLLKSDLKRRYQTCTLNIGIRVAVPQNYVVILAKLTDPDPTSRGIPIIQVANGLIDSGYRGSIRAVLFFEKSCIIPKNGLAIRLSLVKLASPNLNTRVLFNLSDITPHLECGPDFSTSIETAVRLGSGETKPLLPPSGGGIWAGTGCRALACLYNDRVCKASHYTSSDKNIAFVVRYNDSTSVLGLKDFPTAEDETFVRFYTSGQFATLIPFFETFTPKRTEDAAYDIAAPGDIRLGALSSTTIMIQQRYVCMDDSVIPCIFGRSSMNLRGLIIIPSRWLPNSWLTITICNLTEMTVMIRCGDRIAQLLLVDHESATLIPPTNDTTGMFPTVGKCRRPGASVGEPKWRETLEFDTEAYSSERQFSGFGSTGI
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TM9S1_BOVIN
Sequence: MTVLGHPRSWSCRWWPLLLLLLLTGREPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRVLCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETASAGSGDDFDQSDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTLVHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGTVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD
What is the function of this protein?
Plays an essential role in autophagy.
What are the official names of this protein?
Transmembrane 9 superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Protein: TIG_BUCAI
Sequence: MNFFMEKNKDAGHRVTIKIPKTTVNNSLLQEFIKIRKTTKINGFRKGKTPIRVIQEKYGSAIYYDIFKKLMQKFFHEFIKTEKIKIIGSPKFYIHQDEDKKKEYFEYSVIYELYPQFQIKDIKQIKVNKINVEITEEDIKKNIETNKNKKNIWNPVNKAVKSYDRVTINYCIYEKNKKIKKFDKDNISFIVSKNTLIPQLNYKIINHFVNDIIFFKIKFHAFHPEKELQNKDITFKIKIIKIEKKQELESEKSNKKNITEKKTIQTDYQTIKNNLHSQINIITDKYLENQIIQKIVEKNILLLPPLLFQKEIKNLYKQYTKQYQEENSNILEKKYHMSLDSEVKKRLYFQIIIEQIILNNKLFADENNIQKLIKKISSNYKNPMEIIKLYNKNKNLKNTMKNIELERQAMLLLKKSIKIEKQNWNFERFLNYNWASHEELML
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GLND_RHIME
Sequence: MARHETSFPEILDVAALRARCDFIASAHAEQREPMRRALLAAFKEANVAGRAKARELLAADGAGIKCAERISWLQDQLITLLHDFVLNQVFDAAKAPEASRIAVTAVGGYGRGTLAPGSDIDLLFLLPAKKAVWAEPAIEFMLYILWDLGFKVGHATRTIEECIRLSRADMTIRTAILECRYVCGSAALANELETRFDHEIVRNTGPEFIAAKLAERDERHRKAGDTRYLVEPNVKEGKGGLRDLHTLFWISKYFYRVKDSADLVKLGVLSKQEYKLFQKAEDFLWAVRCHMHFLTGKAEERLSFDIQREIAEALGYHDHPGLSAVERFMKHYFLVAKDVGDLTRIFCSALEDQQAKDTPGITGVISRFRNRVRKIAGTLDFVDDGGRIALAGTDVFKRDPVNLMRLFHIADINGLEFHPAALKQVTRSLGLITPHLRENEEANRLFLSILTSRRNPELILRRMNEAGVLGRFIPEFGKIVSMMQFNMYHHYTVDEHLLRSVDVLSRIERGLEEEAHPLTAMLMPGIEDREALYVAVLLHDIAKGRPEDHSVAGAKVARKLCPRFRLTPKQTEMVVWLVEEHLTMSMVAQTRDLNDRKTIVDFAERVQSLERLKMLLILTVCDIRAVGPGVWNGWKGQLLRTLYYETELLLSGGFSELSRKERAKHAAHMLEEALADWPKKERQAYVRLHYQPYLLTVALEEQVRHAGFIREADRAGRTLATMVRTHDFHAITEITVLSPDHPRLLTVIAGACAAAGANIVGAQIHTTSDGRALDTILVNREFSVAEDETRRAASIGKLIEDVLSGRKRLPEVIASRTRVKKRSRAFTVTPEVTISNTLSNKFTVIEVEGLDRTGLLSEVTAVLSDLSLDIASAHITTFGEKVIDTFYVTDLVGSKITSENRQMNIAARLKAVLAGEVDEARERMPSGIIAPTPVSRVPHGSKTTKAET
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: NUSA_MYCLE
Sequence: MNIDMAALHAIEMDRGISVNELLDTIRSALLTAYRHTQGHQIDARIDIDRKTGVVKVIAREVDDDGNVISEWDDTPEGFGRIAATTARQVMLQRFRDAENERTYGEFSTREGEIVAGVIQRDSRANARGLVVVRMGSETKASEGVIPAAEQVLGESYEHGNRLRCYVVGVTRGAREPLITLSRTHPNLVRKLFSLEVPEIADGSVEIVSVAREAGHRSKIAVASRVPGLNAKGACIGPMGQRVRNVMSELSGEKIDIIDYDEDPARFVANALSPAKVVSVSVIDQTARAARVVVPDFQLSLAIGKEGQNARLAARLTGWRIDIRGDSPPCSAGQSEQNASHGMAHER
What is the function of this protein?
Participates in both transcription termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusA.
What is the protein family that this protein belongs to?
Belongs to the NusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EOGT_MOUSE
Sequence: MLMLLVFGVLLHEVPLSGQDKAHSEADDAPGKALYDYSSLRLPAEHIPFFLHNNRHVASVCREDSHCPYKKHLENLNYCWGYEKSCAPEFRFGSPVCSYVDLGWTDTLESAQDMFWRQADFGYARERLGEIRTICQPERASDSSLVCSRYLQYCRATGLYLDLRNIKRNHDRFKEDFLQGGEIGGYCKLDSHALVSEGQRKSPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHVNNSFSTDVYIVMWDTSTYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIHYITWRKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWPFKKKHDEL
What is the function of this protein?
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc).  Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.
What are the official names of this protein?
EGF domain-specific O-linked N-acetylglucosamine transferase, Extracellular O-linked N-acetylglucosamine transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: YIAX1_KLEPN
Sequence: MKNNTGYIIGAYPCAPSFHQKSEDEEKAFWRQLADTPDIRGLEQPCLEHLHPLGDEWLMRHTPADWQIVVTAIMETMRRRGGNGGFGLASSDEEQRKACVAYYRHLYQKINAINAANAGKIVALELHAAPCASNPNVAQATDAFARSLKEVASWDWSCSLVLEHCDAMTGPAPRKGFLPLENVLETLAGYEISVAINWARSAIEGQDTTLPLTHTRQASQAGKLGALMFSGTTLNGEYGEWQDLHAPFSPFCAQSLMTHTHVRELLACAGSDALQFLGFKLLEINPDADVNHRIAILRDGIAALNKAQQ
What is the function of this protein?
Member of the yiaKLX1X2PQRS operon; however YiaX1 is not required for L-ascorbate utilization under aerobic conditions.
What are the official names of this protein?
Uncharacterized protein YiaX1.
What is the protein family that this protein belongs to?
Belongs to the YiaX1 family.
Protein: LPXD_SHEFN
Sequence: MKVTLKELSQLLGATIKGDATLEITSVATLEDATQGQLSFLANSKYRAQLEATQASAVLLSEKEASCYHGNALIVSDPYVGFARVAQLLDTTPKETPGIHPSAQIDTSAILGDGAAIGANAVIGANVILGENVQIGPGCVVGESSIIGSNTRLWANVSVYHNVHIGHDCIVHSGTVIGSDGFGYANERGNWVKIPQTGGVRIGNHVEIGACTSIDRGALSHTEIHDGVIIDNQVQIAHNVVIGQNTAMAGGSIIAGSSTIGKYCIIGGGSAVAGHLSVADGVHISGGTNVTSVIREKGVYSSATIAMENKLWRRNTVRFRQLDELFSRVKTLEKSAKGSE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: METAS_THINJ
Sequence: MPLVAHTRLPTFERLKQEGQTVLSEDYAFQQDIRELHIGFLNMMPDAALAATERQFLRLVNESNLIAQFHIHPFTLGTLPRGDKAQAHIAQYYDKFEDLQEQGLDALIITGANPAAPHLEDEPFWDGLCEVVAWAQENVTSTLCSCLASHALVQHLWGIRRRPLGFKRWGVYSHAVTMPEHPLVNDLNTRFDVPHSRFNQIDREPLEAVGVQVLVESTEAGVHMAVSPDLFRMVFMQGHPEYDTVSLLKEYRREVTRWFDGTRADYPPFPQNYLRPKAKAILNEYRLEQEKAKRLGKPLPDFPEKLLLPMLHNTWCDTAKVFYSNWIGKVYQLTNNDRRKPFMEGVNPDDPLGLRQQLGI
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.  In vitro, can also use glutaryl-CoA as acyl donor.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_WIGBR
Sequence: MNMIKKNKKKSFLCTIFSTINVLHGLIAISPIYIIKESFVNNLGFKIDKLAIFGILSIIFWTLFFIIFLKYLILIVSINNSGEGGILTLMSITAKKINSKSTFVIVILGLISMCLFFGDIIIIPSISIISVIEEISIYYLSFEKFIFIISIAIFTFLFFIQKKIKNEFNNIFSFLISIWFILVGLIGLKGIYINPEILLAINPKYLINFFKHYKLNAFFVFGTLILLISISEILYINIGRFSKLEIRKSWLFFVFPMIMINCFGQGSIILLYPESISHPFFFLVPDWARFFTFTFAIIISIISSQNIISSIFYLTRQAVRLGYLPNIKIFYTSEVKSRRIYIPCINWIFYLSAVIQISIFKNLHNLILIYGIGSIITMSLTTFFSLLFFKKKFEKFKILKITFLLTILILEFFIFISNSYKIICGGWFPIVFGIIFFTIMITWKVETFNLLLHTHNNSNSIKLFIKNLRKNNLLKVNGTSVFMSSMDNTIPLSIIHNIKHNKVLHEKIIFLNIKTEDSPFIKKECRVEIEKLNNGFWGVKAYYGFKETPDIKEIFHFCNLLGISLNIMETSFFISHESLILGKRPWYLAIRAKLFIFLKRNSLGSTYQYSIPLDRVIALGIQVKI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUFE_YERPE
Sequence: MAGLPDRDKLIRNFSRCLNWEEKYLYIIELGGQLAPLTEQQRHPENLISGCQSQVWIAMTLSAEGHVIFAGDSDAAIVKGLVAVVFILYHDLTPQQIISLDVRPFFADLALSQHLTPSRSQGLEAMIRAIRTKVANLSAH
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_ALKOO
Sequence: MKIVIDAMGGDHAPFVTVEGAVEAVKNYDIHIILTGNQPLIENELVKYDYPKERIEVIHCSEQITNEDKPVISIRRKKDSSMVVGLKLVKEKKADAIISAGNSGALLAGGLLVLGRIKGIDRPALAPVYPTAKGISVLVDAGANAECKPRNLLEFGIMGSIYAEKVLEIKNPKVCTVNIGIEEEKGTELVKEAYQLCKEGPFNFQGNVEAREIPNGYADVIVCDGFTGNVILKLTEGLASSIFSLLKEEFLKNTFTKIGALLLKPGLKSFKKKLDYTEYGGAPLLGVKGVLIKAHGSSDGKAIKNAVGQAIKFMDNKVLEHISEGVSSLGDDEFE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.