PharMolix/UniProtQA huggingface dataset:
Protein: PURL_STAAC
Sequence: MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_XANAC
Sequence: MEHVDSPLYLGLMSGTSADGIDAALVRFADDTHRRCELVAGTTVAWEPQLRETLVALGQGAETVAIDALGQLDAQVGLAFAAAANQLIGDSGVERRQIRAIGSHGQTIRHRPNASPAFTWQIGDASRIAEHTGITTVADFRRRDVAAGGQGAPLMPAFHLAMLGAGDEDRAVLNLGGIGNLTLIPRDGAVRGFDTGPANALLDSWCQRHHGTPFDADGAFAASGRVDAALLQALLADPWFALPPPKSTGREQFHLDWAVQAMGNARLDAADVQATLLELTAASVADALLRLQPTTRRVLVCGGGVRNPVLLARLAARLPGAMVESSARYGLDPDYLEAMGFAWLAAELLAGRAANLPSVTGAAGPRLLGAIYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: MNMC_CUPPJ
Sequence: MSRALEPAEPILSAEGTPYSPRYDDVYHSTEGGLAQAHYVFLGGNGLPQAWAGRDQFVIVETGFGQGLNFLATWQAWRNDPQRCRRLHFVSIEKHPFTREGLAQLHAGLADMLPLAQQLQAAWPDALPGLHRLAFEDGGVTLTLALGDIEAVLPKLVAGADAFYLDGFSPSRNADMWSPLVFRGLARLARPGATLATYTAAGFVRRGLREAGFDARKAPGFGGKRDMTVATFCPVWKSRRHAPTPAPEWKVRHAIVIGAGLAGCAVTERLASRGWQVTLFDVHDGPARQTSSHRAAAMHAHISSDDSLLSRLSRAGNQYALRAWAALAGAGQPVGWHGCGVLQIGENEAEAEAQRAALEALGLPESFVRWMSPGEAASQHGAGVPRGGLWFPQGGWVAPPDICSAQLRRAGDAVQSRFGTRVERIRRRDDEWEAIDEDGAVLASAPILVLANAHEAPRLAPMRHQVMRRVRGQLTTLAPGQVTALGSWPDCVVTGAGYLLPVSEDGSARVGSSYEADDGPLVARTEVHAANLDRLAGLLPQAAAAAGNLDAAAMSGYVGVRTVSHNRLPLIGQMPDEAAAIAAAPSLRGAHLRDIPRVPGLYAALAYASRGLTWAALGAELLASQIEGDPLPLEADLVDAIDPARLLLRALRHGQVGREEGHSSGLSG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECO1_YEAST
Sequence: MKARKSQRKAGSKPNLIQSKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKYHTLQLHGRKWSPNWGSIVYTERNHSRTVHLSRSTGTITPLNSSPLKKSSPSITHQEEKIVYVRPDKSNGEVRAMTEIMTLVNNELNAPHDENVIWNSTTEEKGKAFVYIRNDRAVGIIIIENLYGGNGKTSSRGRWMVYDSRRLVQNVYPDFKIGISRIWVCRTARKLGIATKLIDVARENIVYGEVIPRYQVAWSQPTDSGGKLASKYNGIMHKSGKLLLPVYI
What is the function of this protein?
Required for establishment of sister chromatid cohesion during S phase but not for its further maintenance during G2 or M phases or for loading the cohesin complex onto DNA.  Interacts with the three known alternate replication factor C (RFC) complexes, suggesting that these complexes have essential but redundant activity in cohesion establishment.  Acts by acetylating the cohesin complex component SMC3.  In vitro, possesses acetyltransferase activity where it can acetylate itself and components of the cohesin complex (MCD1, IRR1 and PDS5), but is unable to acetylate histones.
What are the official names of this protein?
N-acetyltransferase ECO1, Chromosome transmission fidelity protein 7, Establishment of cohesion protein 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ECO subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin.
Protein: SYK_XANOP
Sequence: MTEQIPAPQPPADENSLIAERRAKLGALRGQGIAYPNDFVREHFAGDLQAEFADADTWTPDALEASGRTVKMAGRLMAKRVMGKASFAQIQDESGRVQLFLQGNVLGDAYTAFKGWDVGDIVAVEGGLTRTKTGELSVKASALRLLTKSLRPLPDKWHGLSDVEQRYRQRYVDLIVTPEAREVFIKRSKIIRAMRAWLDARRFLEVETPMMHYIPGGATAKPFTTHHNALDLDLYLRVAPELYLKRLVVGGLERVYEINRNFRNEGVSTRHNPEFTMLELYEAYATYHEIMDLTEQVIRDTAQSVLGTTQVSWDGADIDLAPAFRRWRMDEAVRHHNPEISAADCTDRDALLRHCERLKIRVKPSYDWGKLLLEIFEATVEHTLVQPTFITDHPVEVSPLARSSDTEPGYTDRFELFINGKELANGFSELNDPEDQAARFQAQVQAKDGGDDEAMHFDADYIRALEYGMAPTGGLGIGIDRLVMLLTGSTSIRDVLLFPYMRPEA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_PASV1
Sequence: MASKSGKDVTVKVENTNGRGRSRSRSRSRSRARNKNVKITINSKPGASGGQRRRGKPQSDKRVRSIVKQQLDKSGVTGPKPAIRQRATATLGTIGSNSSGKTELEACILTNPILVKDNTGNNTFGPIVALGAQYSLWRIRFLRIKFTPMVGQSAVTGTVVRASLNPTATPSSTGWSGLGARRHIDIVVGKAATFNLKASDLSGPREGWWLTNTNDSGDSTLGPSIEIHTLGTTMSAYQNGPFTGGLFLCELQAEWEFSGYAANPALLSLEKNRDDDAEVSFDGQQGEPLTMVVAEDSLFNKVATRRSTFTRGIARDGQTKSETIWQVVDTAVSAAETVVPPPFGWLIRGGYWFVKKLAGRTKLRNGKQTSSYVCYASYQDALSDKPAICTGVAANFYAGRTETARANLHFTQMNEPSTGVGETPTAFRMYRAAPDDIVYLRFKPETVNISVSPAARLFLARKYTAHSLKVKGNSGTTRIHCVVKVNDPMWYSPDWEQVAQPGPIPGVSLLGGTTTIGIVTAAYQAHMWGLHIATAFIVQVTKDINPACSTSCVLTKELNDQHLKTVAGQTSFNWSLRAGETYLMMSFGAHTSAVGEWVWNDADISVGYTIYNSPLTPCLLLTEGSFHIVLPAKRGLIPLASTELFTVRDQDSIPQTTEPPAEEDVGDNETEDESDDEDLDHFDLHDSSGSEPEDEDVENNRVTLLNTLVNQGVDLARAAKISKRAYPTLAEKTRRSVFMDSLIAGCGPSSAWSEACKAARKVSFKEPISESRGHAE
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes.  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: Y123_PYRFU
Sequence: MEALAELIKRKVPNEGLIIEVGVGFYLKVAKKLKEYGFNVVVVDINQEAVKNAIKERIPGFVDDVFNPNLKIYLKARAIYSIRPNPEIMMALLTLAKKVKVPLYIVPLSGDVPPREMKLINYKGISVYVWEP
What are the official names of this protein?
UPF0146 protein PF0123.
What is the protein family that this protein belongs to?
Belongs to the UPF0146 family.
Protein: LEU1_BORPD
Sequence: MLANPATKYVPFAPFARDFSERTWPSRRITQPPIWMSTDLRDGNQSLIEPMSVERKLRFFEQLVKIGFKEIEVGFPSASQTDFDFVRKLVDEKRIPDDVTIIVLTQSREDLISRTVEAAAGAKQAIVHLYNACAPAFRKVVFNMSKDEIKQIAISGTQWVKQYMAQHPETQWRYEYSPEVFSTTEPEFALEVSNAVADVWQPTPECKMVLNLPATIEATTPNLYADQIEWMHKNLARRDSIVLSVHPHNDRGTAVAAAEFAVMAGADRIEGCLFGSGERTGNVDLVTLALNLYTQGVHPGLDFSDIDEVRRCAEYCNQLPVHPRHPYAGDLVFTAFSGSHQDAIKKGFAQQKPDAVWEVPYLPIDPADLGRSYDAVIRVNSQSGKGGVSYLLEQEHGLVLPRRLQIEFSRAIQRVTDETGREVTADDVHTIFNREYLEQHSPWKLVRHRIDGDPAGGQGKQFSIQVELDYNGERRVVTGSGDGAISAFVAALGIPVRIMDYHEHAIGTGTDTRAASYVELRVGDSATGFGVGIDRDIVTASFQAVLSAVNRHLANGVTVTESETAQAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: DER_STRU0
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRKFSLIDTGGIDDVDAPFMEQIKHQAQIAMDEADVIVFVVSGKEGVTDADEYVAKMLYRTNKPVILAVNKVDNPEMRNDIYDFYALGLGDPYPASSVHGIGTGDILDAIIEKLPVEEEEINDNTIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTHFTDQDGQEYNMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLLVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDLLEKDNHTVAKWEADIRDQFQFLSYAPIIFVSALTKQRLNKLPELIKKISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVIFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ASTB_PSEMY
Sequence: MTAYEMNFDGLVGPTHNYGGLSYGNVASQSNSQAISNPKEAAKQGLAKMKALMDMGFKQGVLAPQERPDVAALRRLGFTGSDPEVIARAAREAMPLLVASCSASSMWTANACTVSPSADTADARVHFTAANLNCKFHRSIEHPTTSRVLQAMFASQEHFAHHPALPAVSQFGDEGAANHTRFCKSYGEPGVEFFVYGRSAFDSRYPAPARYPARQTLEASQAVARLHGLSEEGVVYAQQNPAVIDQGVFHNDVIAVGNGEVLFYHQDAFLDTDKVLGELGSKLAGRGGNFQAVCVPNSAVSVEDAVKSYLFNSQLLTRADGSMLLVVPEECRNNASVWRYLEQLTAGNGPIREVRVFDLKQSMQNGGGPACLRLRVALKEQELAAVNPGVVMSLELHDRLVAWVDKHYRDRLSEADLADPQLLIECRTALDELTQILKLGSVYPFQMT
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: RL34_STAHJ
Sequence: MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DX39B_PANTR
Sequence: MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
What is the function of this protein?
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint.  Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity.  Even with the stimulation of RNA, the ATPase activity is weak.  Can only hydrolyze ATP but not other NTPs.  The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA.  However, ssRNA stimulates the ATPase activity much more strongly than dsRNA.  Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro.  The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly with [] reporting a stimulatory effect.
What are the official names of this protein?
Spliceosome RNA helicase DDX39B, 56 kDa U2AF65-associated protein, DEAD box protein UAP56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: FCL2_ARATH
Sequence: MADNTGSEMKSGSFMLEKSAKIFVAGHRGLVGSAIVRKLQDQGFTNLVLRTHSELDLTSQSDVESFFATEKPVYVILAAAKVGGIHANNTYPADFIGVNLQIQTNVIHSAYTHGVKKLLFLGSSCIYPKFAPQPIPESALLTGPLEPTNEWYAIAKIAGIKMCQAYRLQHQWDAISGMPTNLYGQNDNFHPENSHVLPALMRRFHEAKANNADEVVVWGSGSPLREFLHVDDLADACVFLMDQYSGFEHVNVGSGVEVTIKELAELVKEVVGFKGKLVWDTTKPDGTPRKLMDSSKLASLGWTPKISLKDGLSQTYEWYLENVVQKKQ
What is the function of this protein?
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
What are the official names of this protein?
Putative GDP-L-fucose synthase 2, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase 2, AtGER2.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Protein: GCH4_STAEQ
Sequence: MTEFDLSTREGRWKHFGSVDPVKGTKPTTKNEMTDLQSTHKNFLFEIEEVGIKNLTYPVLIDQYQTAGLFSFSTSLNKNEKGINMSRILESVEKHYDNGIELEFNTLHQLLRTLQDKMNQNAAGVDVSGKWFFDRYSPVTHIKAVGHADVTYGLAIENHTVTRKELTIQAKVTTLCPCSKEISEYSAHNQRGIVTVKAYLDKNNDVIDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWIEGFDIECRNEESIHQHDAFARLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: NU4LM_DRONF
Sequence: MIMFLYSSFSMILFILGLFCFVSNRKHLLSMLLSLEFIVLILFFMLFIYLNLMNYENYFSMMFLTFSVCEGALGLSILVSMIRTHGNDYFQSFSIM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MTNN_BACC1
Sequence: MRIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLERYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQAEENIQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RN170_BOVIN
Sequence: MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSLALIATLVYALFSRNAHQNIHPENQELVRVLREQLQTEQDAPAAARQQFYTDMYCPICLHQASLPVETNCGHLFCGTCIVAYWRYGSWLGAISCPICRQTVTLLLPVFGENDQSQDVVSLHQDISDYNRRFSGQPRSIMERIMDLPTLLRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLLLIYISIMYREVITQRLNR
What is the function of this protein?
E3 ubiquitin-protein ligase.  Plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway.  Also involved in ITPR1 turnover in resting cells.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF170, RING finger protein 170, RING-type E3 ubiquitin transferase RNF170.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DTMLH_HAHCH
Sequence: MKLSMVMVLLVLAGQLSGCGGNDDNNSERTHESGDSNGDVTTPDNDASSNDEDDAALEPTQLRSVEFAQSHVLPPGGLSWDLKESGELQLVEKRDTLVLATFDEAVQAAEVRVYDKNHQLLSSLNLSKPSDLPPTEGDDLPYSDDAWSAVIPSDDMSKGVNIRVVAQGKSASEIVTPALHPELDLTIQSLPFLIYGANESNIPFKIDDLKVMFADPDTAGQGFAGMPFSKTHIVNHPLGVFESDYLIAPPSGSAPAKKVESAADPDYSKPILDMVWHIEYATGDMALNKITFAPSMLIDHSKAGPIKTRGFGGMAYTGSGASMGYPSLGLLWHEGGHALGLPHSLSGSKDLRGPYYPYAEGSLSGSAWGYDQHKGYFRSPLTAPTSRYFVCNGERGGGVFQKTPEGRCYRFDPMHSADEQKDPDAAFPLFSDFNAGKMQRWVRNRARMNPSNDGFQVLDDNGDWADFVPETKHYAGWHIKEHYPVSFDKTTDFIMITYSLAGTDAASHFYNPIRYKGNAIEYVDAINQDGLNSINADISSGARAKYSDYCRRQGCDFTLKVTYEDGSTSYRVLKGSARKDWQPSVWKDDYLNENSKDSYLFWAVALVAPDGAPKVKKLELLDTPILWNLSPTAVMGAEALVVKQL
What are the official names of this protein?
Dictomallein-like protein.
What is the protein family that this protein belongs to?
Belongs to the dictomallein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1667_HAEIN
Sequence: MVVFKSTLKLSLFALSLSMMMSGCVLVGLSKNDQSKSLYGINLSHLSLAERKELEEAIYADQQRLTEEKQTLLNMTLTHEIGDHKLQFKPLLARLYASRKYAPLWTDNAAARQLLRDYAAMVASGISKSSATSLETLALVEQQGGLVYDVLLSDILLDYLYYTQNVRSQASNWLYSSAQYQAQQPENDHIQRWLSAVENNQLLDFIQSLAGENHLYRQTIQSLPMFIPTSKESNITQKLAMNAQRLRVIPDFHNGIFVNIPSYKLQYYRDGDLILESRVIVGTNSRRTPVMYSKLSNVVVNPPWNAPIRLINEDLLPKMKADPNYITEHNYSILDNQGNVVDPASIDWESIDNKFPYRVRQAAGDSALGNYKFNMPSSDAIYLHDTPNRGLFNRKNRALSSGCVRVEKSDQLASILLKEAGWTETRKNTVLASKKTTSAPIRSDNPVFLYYVTAWIENGNIVNLPDIYGYDRQINLAEINWDLVKKYLQ
What are the official names of this protein?
Putative L,D-transpeptidase HI_1667.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RUBR3_CHLTE
Sequence: MQKWVCVPCGYEYDPADGDPENGIEPGTAFEDLPEDWVCPVCGVDKSFFEPVS
What is the function of this protein?
Functions as an electron acceptor for pyruvate ferredoxin oxidoreductase (PFOR).
What are the official names of this protein?
Rubredoxin 3, Rd 3.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: RRG1_SCHPO
Sequence: MILEDTDLPLSHEQPSYSQIKDVLDKIPTGEHLWDLPKYEEKIILNWLIKLLATNLEWITVEEERDYLVSTICERIAERSGRLAAPTRKREFSLSNGVSVVLREPTMTYNTLGFKTWGSAPLLSANLPKWEDLSNSINALELGAGTGLVGISAAIQLGWQVVCTDLPDIVENMQYNVDYNSELIQQYAGSVSCHVLDWMNPPDDDNRPSWLIKPFQRIIASDCIYETHFGELAIALFRKYLAKDGIVITEYPLRETHLEEIGVFEKGMDAAGFERQMGEEIGEEDFGSLYPVTCRWSRWKYHG
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 2 and elongation factor 3A.
What are the official names of this protein?
Protein-lysine N-methyltransferase rrg1, Elongation factor methyltransferase 2, Rapid response to glucose protein 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SURA_XANAC
Sequence: MTKPFSVVLASLLAITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRENQLPPDDVLQRQVLERLVLVKLQVSRADGNGIRVSDEELNRAIASIAQQNGTTVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEGEVDTALAQQAATGSQYHLAHILIGLPEGANAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSLDEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKMVTEYHARHILVRIGDNQTEAQAKAKIDTIRARIVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVESLTDGAVSEPFRTQAGWHIVQRVGSRQTDVSAENQRAQVRETIGRRKLEEEYNRYLQELRGEAYVSYRTGDRADDNATAAPAKSPDPAAPSPPPAKPTR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: PURL_SYNY3
Sequence: MTAPFTPAEIAAEGIKPEEYEDIVQRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLSNFPTEGERILVGPGENAGVVDLGDGLRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIAILNSLRFGNLDDARNRRIFTGVVDGISHYGNCVGVPTVGGEIYFDPAYSGNPLVNAMALGLMETEEIVKAGASGIGNPVLYVGSTTGRDGMGGASFASAELTDQSMDDRPAVQVGDPFLEKSLIEACLEAFKSGAVVAAQDMGAAGITCSTAEMAAKGGVGIELDLDKIPVRETGMVPYEYLLSESQERMLFVAQPGREQELIDIFHRWGLQAVVAGQVIADPIVRIFFQGGIAAEIPATALADNTPIYHRQLLDQAPDYAQQAWQWQESDLSPAAIAGIEIAGQKQSWNEVLLTLLDSPTIASKHWVYRQYDHQVQNNTVIVPGGADAAVVRVRPLDAKPEECVIGVAATTDCNARYVYLNPLEGAKAAVAEAARNLSCVGAEPLAVTDNLNFGSPENPVGYWQLALACEGIAEGCRQLNTPVTGGNVSLYNETLDSNGRPQPIYPTPVIGMVGRVENINKVVGQGWRNSGNGIYLLGSNDGNTLGGSEYLAVVHHTVAGQPPQVDFDLEKAVQKACRHGIAQGWVNAAHDCAEGGLSVALAEMAIASQLGAEINLPDSDQRLDNLLFGESASRIVVAVAPEHQPAWENYLAGQSLPWQKLGVVGTAQGNLTFIDAQNNALIDLPVSALTEPWQTAIARRLKS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SINFN
Sequence: MVTDQGDRASEADGGPVRHIPVMLAEVLAALEPAPGKVILDGTFGAGGYTSAILDAGADVIALDRDPTAIAAGQPMVAAAGGRLRLIHSRFSELADHVPEGGLDGIVFDIGVSSMQIDEAERGFSFQKKGPLDMRMSAAGVSAADVVNRAKVSDLIRIFGFLGEEKQAGRIARAIEKRRAEAPFETTRNLANLIETVTPRKAKDKIHPATRVFQALRIFVNDELGELANALFAAERVLKPGGRLVVVTFHSLEDRIVKTFFQDRSGKAGGSRHLPLVTARDATFTPVGKPMVAASEDEASRNPRARSAKLRAGVRTPAASPGNDLSIFNLPELASLARLGG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.