PharMolix/UniProtQA huggingface dataset:
Protein: OLFL3_BOVIN
Sequence: MGPHTQLLILLLLSWLGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEVDEKVTGGPGTKGKGRRNEKYDMITDCGYTISQVRSMKILKRFGGPAGLWTKDPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYYARRPPGGPGGGGELQNTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV
What is the function of this protein?
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development.  Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side.  Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity).  May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes (By similarity).
What are the official names of this protein?
Olfactomedin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the OLFML3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VUP1_ARATH
Sequence: MMDTFSCNSYEQNHPHDDDIDIDAHDHDSHGGDHQEESGWTTYLDDFSNQYRTTHHEENDHQDKSSYSLLATSTSLVSDAATHAFSGKSFPVNFPAKLKFGRGRTKKICEDDSLEDTASSPVNSPKVSHFEHIQTPPRKIEDYVSSSFVMGNIRGMGDHQIQIQEGGEQKVTLMRNLIDGNNNNNNNNMDLRSRGLCVVPISMLANFNGRC
What is the function of this protein?
Involved in the regulation of xylem development and growth.  May regulate secondary wall formation during vascular development by modulation of brassinosteroid, gibberellin and auxin hormone signaling pathways.
What are the official names of this protein?
Vascular-related unknown protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SSB1_NOSS1
Sequence: MSINIVTLVGRVGTDPDIKYFESGSVKCRLTLAVNRRSKNDKPDWFTLELWDKTAEVAGNYVRKGSLIGVKGSLKFDSWSDRQTGVNRSTPVIRVDQLELLGSKQDRDGGSSDFAPENF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: NDHJ_PSINU
Sequence: MQGRVSVWLSQHKLAHRPSGFDYQGIEIIQIKSEDWPSIAVALYIYGFNYLRSQCAYDVMPGGFLASVYHLTKLQDNADQPEEVCIKILVSRESPKIPSIFWVWKSADFQERESYDMSGIHYESHPRLKRILMPESWIGWPLRKDYVVPNFYELQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: DNAA_THEYD
Sequence: MNEINKIWQKILEIILEKVGESTFELWFSPIKLLDIKNSEAFIEVPNRFFKDWIEDNFPSIISDSFYQITGSQVEVKYIITGKEHETGLIEEKKQVIKKGNLNPKYTFDTFVVGPSNQFAHAASFRVAENPGFAYNPLFIYGGVGLGKTHLITAIGNYILDKKPEMNVCYISSEQFTGEFVSAIRHEKMPEFRNKYRTVDVFLVDDIQFIAGKDSTQEEFFHTFNELYSKQKQIVISSDRPPMEISDITDRLRSRFGMGLIADIQPPEIETRLAILYKKADMEGVKLPEDVAYFIASRVKSNVRELEGSLIKLCAYTSLTKVPISMDVAKYVLRDLLPDENKPITIELIQKAVCEAVGLKIQDIKSKKRTKEISNARKLAMYITKKLTNLSLAEIGNAFGGKDHATVIYACKQVEKEKEKDESISRLIDSIIKKVTGQ
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODF_SYNY3
Sequence: MAYALPNLPYDYTALEPCISKSTLEFHHDKHHAAYVNNFNNAVAGTDLDNQSIEDVIKAVAGDASKAGIFNNAAQAWNHSFYWNCMKPGGGGQPSGALADKINADFGSFDAFVEAFKQAGATQFGSGWAWLVLDNGTLKVTKTGNAENPMTAGQTPLLTMDVWEHAYYLDYQNRRPDYIADFLGKLVNWDFVAANLAAA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: VPS10_CANDC
Sequence: MRNNNCNWLIFLLAFILSLTTAYTPDISVVKNNSPAREIKYFDDSSTLLVLRDDHLLISKNDGKSFEEISDIKDPIIYFEMDPTNKNRAFAMTLSQKQYITEDQGNRWRTFEIDLFNGEMASIPKITFNFENPNYLMISNYECPEGQRLNRNCKHRYFYTKDGFKSKPTKLSVDAHVCRFAKSTKTSKIGNSETVFCTVNQLNSYGHIVESHLYNSNDFFQTKNEIKIKPLDSSSGEIIDIKIEEDFMIVVSRMDKFNEKSLINAYVSRDGENFVRADLDIDIKYGVMSFLPSSVSSLFLTIMDYNSRAFQTASFYGSDSSGLHFTKLLDNVAGGNIQKIENIDGAWIANIGVDSNNPYDGDKSLLDNLFGGTYAKDIVSKVSINDGKDWSLIKLNDNSCKIEDDCSLHLWDFTELDGEGKFVTGPTPGILLGVGNKGKNLAHKFDKMKTYVSRDGGVTWDKALDFPAVFAFGDQGNVILAVPYNGKKKYDAAKHFYFSLDQGKSWDKVDLKHPIYPLSILTTIDGTSRKFIIGGIDDSRKSENEYIYSVDFTNAFDGKTCGDDDFEEFVARKSNIDDEPLCIYGHREKFRRRKQDAQCFVNKLFEDVKVIEDPCQCTEHDFECGPGFKLSEKDSANVCVPDRKQLSRLCQSKSELSLPNKVLVEGNKCNMGDKKLEDFVSQETLKCSDYVDGDNGDKQNPNQGDSNQIEVHINDFEGKLAQYQYIAESQDKNAADNIVIKTMDDRVWISNNGGVSFVRVPISDKILGFYAGPIPGQVILITATNLIYVSDDGGATFIKRRIPTQPSPRVDRAIAFHNEKVERFIWFGEECESNGRCTSNAYITDDAGATFNKLMANVKTCDYVGAVLESGDDELIYCSAQNSLDNNKLALFSLKESSSEEPKKVFENIVGYAIAGTYVVVATIDDKKDSLLSKVTVDGDVFADADFPHDLKVEPHQAFTVLDSSSKAIFMHVTTNEKPNFEYGQLLKSNSNGTYFVLALDNVNRNTVGYVDFDKIDGLEGTIIANVVANAQANEGTKNLQTLISHNDGSEWDKLVPPTVDSEGKKYQCTGQPLNKCALHLHGFTERADYRDTFSSGSATGFLIGVGNVGEFLTPMDDSSTATFLSTDGGVTWKEIKKGVYMWEYGDQGTILVLVNAVEETDVLYYSLDEGQTWKEYGFTDYKIKAHDLATVPTDTARKFIIFAQNSKDHRDIQTYTIDFTNIYPRQCQLNLDDPEHDDYEYWSPVHPIGGDKCMFGHESKYLRRANGHTDCFIGSAPLSDGYKLEKNCSCTRRDYECDYNYVRDVNDNTCKLVKGMTSADRKTTMCSKENAFQYFESTGYRKIPLSTCKGGQQFDNWNPKPCPGKEKIFNEYYGREVKGHKLFFLIFIPLIIFLGTVLFVYDRGIRRNGGFKRLGQIRLNDDDDDFNPIENDQIDVVVNKIVKGGVYTVAVLIATVKTIRKIDRMMLEKLGNVIFRRSPGRRNYVSVPNDFDEEEELFGDYQDNLDDELEDAVFNQDDNLVRTPFVDDIEETETEAQQGEQSNPRDERLFDIDDNEEEEQQQEVSKPAPS
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: RS19_LYSSC
Sequence: MGRSLKKGPFVDDHLMKKVEVQEASEKKQVIKTWSRRSTIFPNFIGLTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHGADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ACPS_ANADE
Sequence: MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPAERAYCDARQDRATRYAARFAAKEAAVKALGTPEGVRWLDLVVERGTGAPSLALDGVAADAARRMGVARVHLTLTHDGGVAVAAVILEGAGP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_SHESR
Sequence: MDHLAHHYHAHIAELNRRVAEIVSREALSGLVIHSGQPHRMFLDDINYPFKANPHFKAWLPVLDNPNCWLVVNGRDKPQLIFYRPVDFWHKVSDVPEMFWTEHFEIKLLTKADKVAELLPSDITNWAYLGEHLDVAEVLGFTSRNPDSVMSYLHFHRTTKTEYELECMRRANQIAVQGHLAAKNAFYNGASEFEIQQQYLSAVGQGDNEVPYGNIIALNQNAAILHYTALEHQNPARRLSFLIDAGASYFGYASDITRTYAFEKNRFDELITAMNKAQLELIDMMRPGVRYPDLHLATHGKVAQMLLDFELATGDAQGLVDQGITSAFFPHGLGHMLGLQVHDVGGFSFDERGTHIPAPEAHPFLRCTRILAPNQVLTMEPGLYIIDTLLNELKQDSRGQQINWRTVDELRPFGGIRIEDNVIVHQDRNENMTRELGLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: MOAC_ESCF3
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: COX1_CYPCA
Sequence: MAITRWFFSTNHKDIGTLYLVFGAWAGMVGTALSLLIRAELSQPGSLLSDDQIYNVIVTAHAFVMIFFMVMPILIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSGVEAGAGTGWSVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTTINMKPPAISQYQTPLFVWSVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHVVAYYSGKKEPFGYMGMVWAMMAIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGSIKWETPMLWALGFIFLFTVGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAAFVHWFPLLTGYTLHSTWTKIHFGVMFIGVNLTFFPQHFLGLSAMPRRYSDYPDAYALWNTVSSIGSLISLVAVIMFLFILWEAFAAKREVLSVELTATNVEWLHGCPPPYHTYEEPAFVQIQSN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAND_HELPS
Sequence: MTFEMLYSKIHRVTITDANLNYVGSITIDEDLAKLAKLREGMKVEIVDVNNGERFSTYVILGKKRGEICVNGAAARKVAIGDVVIILAYASMNEDEINAHKPCIVLVDEKNEILEK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_ECOBW
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MTDH_AGABI
Sequence: MAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAKDAVEVTEKVGKEFGVKTKAYQCDVSNTDIVTKTIQQIDADLGAISGLIANAGVSVVKPATELTHEDFKFVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWASAGIRVNALSPGYVNTDQTAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHATYMTGGEYFIDGGQLIW
What are the official names of this protein?
NADP-dependent mannitol dehydrogenase, MtDH, Mannitol 2-dehydrogenase [NADP(+)].
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RN114_HUMAN
Sequence: MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates (PubMed:23645206, PubMed:25165885).  In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity (PubMed:25165885, PubMed:28708287).  Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3 (PubMed:25165885).  May promote the ubiquitination of TRAF6 as well (PubMed:28708287).  Acts also as a negative regulator of T-cell activation (PubMed:25165885).  Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation (PubMed:25165885).  Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C (PubMed:23645206).  This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence.  May play a role in spermatogenesis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF114, RING finger protein 114, RING-type E3 ubiquitin transferase RNF114, Zinc finger protein 228, Zinc finger protein 313.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SAHH_CAEEL
Sequence: MAQSKPAYKVADIKLADFGRKEIILAENEMPGLMAMRSKYGPSQPLKGARIAGCLHMTIQTAVLIETLTALGAEVQWSSCNIFSTQDHAAAAIAQTGVPVYAWKGETDEEYEWCIEQTIVFKDGQPLNMILDDGGDLTNLVHAKYPQYLAGIRGLSEETTTGVHNLAKMLAKGDLKVPAINVNDSVTKSKFDNLYGIRESLPDGIKRATDVMLAGKVAVVAGYGDVGKGSAASLKAFGSRVIVTEIDPINALQAAMEGYEVTTLEEAAPKANIIVTTTGCKDIVTGKHFELLPNDAIVCNVGHFDCEIDVKWLNTNATKKDTIKPQVDRYTLKNGRHVILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQVELWTKFGTPQEYKLGLYVLPKTLDEEVAYLHLAQLGVKLTKLSDEQASYLGVPVAGPYKPDHYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, Protein dumpy-14, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: RL1_CROS8
Sequence: MAKLTKRMRVIRDKVDATKQYDINEAITLLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSSAKGVYIKKVSLSTTMGAGVAVDQSGLSAAAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BACR_HALAR
Sequence: MPEPGSEAIWLWLGTAGMFLGMLYFIARGWGETDSRRQKFYIATILITAIAFVNYLAMALGFGLTIVEFAGEEHPIYWARYSDWLFTTPLLLYDLGLLAGADRNTITSLVSLDVLMIGTGLVATLSPGSGVLSAGAERLVWWGISTAFLLVLLYFLFSSLSGRVADLPSDTRSTFKTLRNLVTVVWLVYPVWWLIGTEGIGLVGIGIETAGFMVIDLTAKVGFGIILLRSHGVLDGAAETTGTGATPADD
What is the function of this protein?
Light-driven proton pump.
What are the official names of this protein?
Cruxrhodopsin-1, COP-1, CR-1.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPARD_CANLF
Sequence: MEQPPGEAAEVREEEEKKEVAEAEGAPELNGGPERSLPSSSYTDLSRSSSPPSLLDQLQMGGDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERICKIQKKNRNKCQYCRFQKCVALGMSHNAIRFGRMPEAEKRKLVAGLTANEGTQHNPQVADLKAFSKHIYNAYLKNFNMTKKKARGILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSNLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGTGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLINVPQVEAIQDTILRALEFHLQANHPYAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
What is the function of this protein?
Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues.  Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.  Once activated by a ligand, the receptor binds to promoter elements of target genes.  Regulates the peroxisomal beta-oxidation pathway of fatty acids.  Functions as transcription activator for the acyl-CoA oxidase gene.  Decreases expression of NPC1L1 once activated by a ligand.
What are the official names of this protein?
Peroxisome proliferator-activated receptor delta, PPAR-delta, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: BHUA_BRUME
Sequence: MKFTRMLVLASTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQSSIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVNALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFDGNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMILKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFADWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWSAGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFIDQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNRGGIDAVWAPGRTFTFQTAFKF
What is the function of this protein?
Heme transporter.
What are the official names of this protein?
Heme transporter BhuA.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GBRA6_CHICK
Sequence: MALLIAWVCVAVSIEKALGGQGDGGDLYSENITRILDKLLDGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILRLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLHSVEVPQESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQRAMRKAARAAALAAALSAATVPAEDEIVSHSDSNCNLKKRVNSVTSQADQSPEASIVSNSASQCQPVSAPPPAPPAPPPVGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEFFEPTAMHLRNDHQSN
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-6, GABA(A) receptor subunit alpha-6.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PYRB_DEIRA
Sequence: MTAASSAGPRPRHLLDFQDWTPERLEAVLDNADTMLQVLDRPVKKVPALQGLTVCTAFFENSTRTRTSFELAARRMSADVVSFAAGNSSVSKGESLRDTIEVLTAYKVDAYVVRHHAAGAAHLVAKYSGKPVINAGDGRRAHPTQALLDAYTIRQEYGSLEGKKVAIIGDIRHSRVARSNAELLPKLGAEVVLCGPATLLPPDLAGQPGVRLTTDPREAVRGAHAVMALRLQQERMNGGYLASLQEYADTYQVNETLMREAESGAIVLHPGPMNRDLEISTEAADGPRSRIIRQVENGQAVRMSVLYHLLVGRA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL11_STRPZ
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTRAQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL30_SHEPA
Sequence: MATKTLKVTQTKSSIGRLPKHRATLTGLGLRRINHTVEVEDTPSVRGMINKVYYMVSVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CLPP_VIBC1
Sequence: MSYQEKNAMSPIIDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSPGGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIKQKLNNLLAEHTGQPLEVIERDTDRDNFMSADQAVEYGIVDAVLSHRGE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.