PharMolix/UniProtQA huggingface dataset:
Protein: RNFA_RHOCA
Sequence: MQDFLLVLLSTALVNNVVLVKFLGLCPFMGVSRKTDAAIGMGLATTFVITVASAACWLVEALILEPLDLKFLRILSMILVIAAIVQFIETVMRKVTPDLHKALGIYLPLITTNCAVLGLPLMYIQGHLSLAMSTLSGFGASVGFTLVLVIFAGMRERLAQLSVPAAFAGTPIAFVSAGLLGLAFMGFAGLVHV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).  Required for nitrogen fixation.  Involved in electron transfer to nitrogenase (PubMed:8264535).
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Nitrogen fixation protein RnfA, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi- pass membrane protein.
Protein: ENDOS_STRP1
Sequence: MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQKGLPSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPEKIPMKPLHGSLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLFWKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVDEYVYKYNLDGLDVDVEHDSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLFIMDSTYMADKNPLIERGAPYINLLLVQVYGSQGEKGGWEPVSNRPEKTMEERWQGYSKYIRPEQYMIGFSFYEENAQEGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKTGGVKGGIFSYAIDRDGVAHQPKKYAKQKEFKDATDNIFHSDYSVSKALKTVMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEGLNKFKKLAQLDLIGLSRITKLDRSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSLKVSGLTGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDTMLSTISNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVANEKVDLQSQLLFGTVTNQGTLINSEADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLATDKEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFDGQLGSETDNISLGWDSKQSIIFKLKEDGLIKHWRFFNDSARNPETTNKPIQEASLQIFNIKDYNLDNLLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTKGDRYSSPVVPELQILGYPLPNADTIMKTVTTAKELSQQKDKFSQKMLDELKIKEMALETSLNSKIFDVTAINANAGVLKDCIEKRQLLKK
What is the function of this protein?
Endoglucosidase that acts as a host immune evasion factor by mediating hydrolysis of the N-linked glycan from the Fc region of host immunoglobulin-gamma (IgG) during infection (PubMed:11406581, PubMed:11598100, PubMed:12438337, PubMed:18182097, PubMed:20357243, PubMed:21619648, PubMed:22551167, PubMed:22747414, PubMed:30102520, PubMed:31092533, PubMed:24668806, PubMed:24753590, PubMed:29760474).  Specifically catalyzes the hydrolysis of the beta-1,4 linkage between the first two N-acetylglucosamine residues of the complex-type N-linked glycan located on 'Asn-297' of the Fc region of IgG antibodies (IGHG1, IGHG2, IGHG3 or IGHG4), thereby preventing interaction between IgGs and Fc receptors and ability to activate the complement pathway (PubMed:11406581, PubMed:11598100, PubMed:12438337, PubMed:20357243, PubMed:21619648, PubMed:31092533).  Shows a specificity for biantennary complex type N-glycans; does neither cleave larger complex type glycans nor oligomannose and nor hybrid-type glycans (PubMed:22551167, PubMed:26156869).  Specifically acts on IgGs; does not act on immunoglobulin alpha, beta, delta or mu (PubMed:11598100).
What are the official names of this protein?
Endo-beta-N-acetylglucosaminidase EndoS, Endoglycosidase S.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: GLAH_SALPK
Sequence: MNALTAVKANTDDLAQRHTGFTLAPSAQSPRLLALTFTADTTRQFLHQVAQWPVQALEYKSFLRFKIGKILDDLCGNQLQPLLIKTLLNRAQGALLISAEGIDDVAQAEEMVKLATAVAHLIGRSNYDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEVTDYVLMMKIDEQNMEGGNSLLLHLDDWEHLESFFTHPLARRVMRWAAPPSKNVSHDVWHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDALETSQNILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYAASHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: AAMP_HUMAN
Sequence: MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQAKLVSATTGKVVGVFRPETVASQPSLGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLATQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVFCVQRPDR
What is the function of this protein?
Plays a role in angiogenesis and cell migration.  In smooth muscle cell migration, may act through the RhoA pathway.
What are the official names of this protein?
Angio-associated migratory cell protein.
Protein: ARF1_CATRO
Sequence: MGLSFTKLFSRLFAKKEMRILMVGLDAAGKTTILYQLKLGEIVTTIPTIGFNVETVEYQYISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKHGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIANKA
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: YEAH_ECOL5
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERSQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RS5_STAA8
Sequence: MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKTVEELYN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: VIRB1_BRUA2
Sequence: MVPFLVLAQQCAPTVAPQTMAAIVQVESGFNPYAIGVVGGRLVRQPVSLDEAITTAQSLEAKGWNFSLGIAQVNRYNLPKYGSTYAQAFDPCKNLKMGSKILEDCYRRAIVKMPGQEQGALRAAFSCYYAGNFTGGFKTKPGSPSYVQKVVASADVTTKPIVVVPMIRKTPDAAAAVAAPVKKRQPADRNSVLVDLHPSSQSMPATGTANAPVRLKTEQPATTDAPPGKDNTDGVVVF
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein virB1.
What is the protein family that this protein belongs to?
Belongs to the virb1 family.
Protein: TIM54_SCHPO
Sequence: MLKTIKSYMPGRNMSIFLGFVAGISGAIYYDRRQKNLIIEKYCSQVRHLADQPMAPLELPRKLKVYLHGPPGDGIYVAREEFEEYIRPIFNAAAIEFETVESKGEGNLLEQVARTVYNKRHNISEVSEPEKNLLSVLKPSVDPPAIVLLGRHALKEFLYGVRYGFSDDIMKRKLETEKLEANNKEEKEEKEGKDDKDDKEDSNDTKNDKKISKNEVDSSLIEASPLTGQVPPKFLDTIAIFPLPNLLGFSNTPKRLSRFFKRRELADELGAIAVNVALSRDVTKFPKQDGTLLLAEEETDWPKQFFTRSDLENRIWTAPFLQDSDEIRFFENIDIFDSTKAKQDKYE
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL33_AZOC5
Sequence: MAKAATIKIKLLSSADTGVFYVTKKNSRTKTDKIVLKKYDPVARKHVEFRETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: S4A4_RAT
Sequence: MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKAGHKEKKEKERISENYSDKSDVENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIADHQIETGLLKPDLKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFSNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDHSFDYLEFRLWIGLWSAFMCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSDFRVGYNTHFSCACLPPDPVNLSVSNDTTLAPEDLPTVSSTDMYHNATFDWAYLSKKECVKFGGKLVGNNCDFVPDITLMSFILFLGTYTSSMAMKKFKTSRYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPHRGWFVPPFGGNPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVVCSFMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTSLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDITEQQPFLSDNKPLDRERSSTFLERHTSC
What is the function of this protein?
Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3.  May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.
What are the official names of this protein?
Electrogenic sodium bicarbonate cotransporter 1, Sodium bicarbonate cotransporter, NBC-like protein, Na(+)/HCO3(-) cotransporter, Solute carrier family 4 member 4.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: HEMH_VIBVU
Sequence: MNNTKKRGVLLVNLGTPEEATAPAVKRFLSQFLHDQRVVDMTRWLWCPILHGIILPIRSPKVAKLYQTVWMKEGSPLMVYSKRQQVELQAKLNCPVEIGMTYGTPSVLDGVNKLQAQGVDEICVLPLYPQYSGTTTGAAYDALAHALRKVAVVPSIQFIRDYHDHPLYIKALAESVRQSWQVQGKGDYLLCSYHGIPQRYADNGDVYPLHCEMTTELLRLELGLDKSQIGTTYQSRFGREEWLQPYTDKTLESLPAKGIKSLDVITPAFSVDCLETLEEISEQGQESFLHAGGEQYRFIPCLNDAPSHIEMMARLVTER
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_GEOUR
Sequence: MKCPFCAFADSKVVDSRPDKGGSTIRRRRECESCGKRFTTHERVEEILPLVIKKDGRREPFDRMKLVAGIQKACEKRPVSVETIERLVDRLEIQMQESGEKEIPSKSLGEWVMAELHSIDQVAYVRFASVYRSFKDITEFMSELQDLLKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: OBG_PSYCK
Sequence: MRFIDEAVVTVKAGDGGNGIASFRREKYVPRGGPDGGDGGKGGDVYVIAEDNTNTLVDYRYTRRHDAMRAENGHSRNCSGKGSDDLFLPVPIGTTVVDTETDEVLGDLIEIGQTLLIAKGGDGGLGNTHFKSSTNQAPRKATSGFEGELKVLKFELKVVADVGLIGLPNAGKSTFIRQVSAARPKVADYPFTTLVPNLGVVDIGRHRSFVMADIPGLIEGASEGAGLGIRFLKHVARTRRLLHLVDIKPIDGSDPVENARVILNELERFSPELANLPQILVLNKIDQVPEEELNELCTHIVAELGWTGIVFRTATLTGEGVDAIKYHLMNEIEREREREIEDPIFADAQKARFERLEAEVRLNTEAQREAYRAARKAAREGTDLSDDDFDDSDDDDDGVEVVYAP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_PHOLL
Sequence: MIIASKFGIGQQVRHKLLGYLGVIVDIDVEYSLEQPQEDDIASNATLRSAPWYHVVMEDDNGQPVHTYLAEAQLAYETSDEHPEQPSLDELAESIRHQLLAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_SHEEP
Sequence: MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPQGMQCSCGALYFTLKPEINNESFVIYMFVVHFSIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKSSSVYNPVIYIMMNKQFRNCMLTTLCCGKNPLGDDEASTTVSKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: LPAR4_MOUSE
Sequence: MGDRRFIDFQFQDLNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSASLFVFCFRMKMRSETAIFITNLALSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCLLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSFYINTHIRMESLFKTETPLTPKPSLPAIQEEVSDQTTNNGGELMLESTF
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.  Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity.  The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA (By similarity).
What are the official names of this protein?
Lysophosphatidic acid receptor 4, LPA receptor 4, LPA-4, G-protein coupled receptor 23, P2Y purinoceptor 9, P2Y9, Purinergic receptor 9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GGTA1_MOUSE
Sequence: MITMLQDLHVNKISMSRSKSETSLPSSRSGSQEKIMNVKGKVILLMLIVSTVVVVFWEYVNRIPEVGENRWQKDWWFPSWFKNGTHSYQEDNVEGRREKGRNGDRIEEPQLWDWFNPKNRPDVLTVTPWKAPIVWEGTYDTALLEKYYATQKLTVGLTVFAVGKYIEHYLEDFLESADMYFMVGHRVIFYVMIDDTSRMPVVHLNPLHSLQVFEIRSEKRWQDISMMRMKTIGEHILAHIQHEVDFLFCMDVDQVFQDNFGVETLGQLVAQLQAWWYKASPEKFTYERRELSAAYIPFGEGDFYYHAAIFGGTPTHILNLTRECFKGILQDKKHDIEAQWHDESHLNKYFLFNKPTKILSPEYCWDYQIGLPSDIKSVKVAWQTKEYNLVRNNV
What is the function of this protein?
Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid.  Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isoglobotrihexosylceramide or isogloboside 3 (iGb3).
What are the official names of this protein?
N-acetyllactosaminide alpha-1,3-galactosyltransferase, UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase, Galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: GLYCO_SHRV
Sequence: MTLPNMKPKRIVLFLVFLNAWVSNAQVTHKPRPDSIVEYSEEWENPIYTTPSHCFEDTFAPVKPEKLRCPHIFDDQNLGLTASKAKILHMDLKPEDTHFEAKGRLLHKVTYQVLCSTGFFGGRTVTRKVLETPMGDNEAQAYKAVDREFPYFPEPLCFWLRDNVAAERVFHFSTPKTVTVDLYSRKYISPDFVGGQCAKSPCPTHWPNVYWVGETQSPECPSIDTEGGHIFTKKDTHRITKAVVHGHHPWGLTKACQIQFCNEQWIRTDLGDLIRIEPNDGTSSLTLPKCQDNVVQMRGNLDDFSYLNHAIVNMAQRSECLEAHSSIVAQQKVSPYLLSKFRPPHPGLGKAHYLQNNTIMRGDCIYEGVAEISENRTTYRNLKGEWKKWSLSRGGEGYDGMTVGTKIVIPDLEKYQSIYDNGMFIPKLLGEVPHPSIVITYNQTDSIETGIFTDGKLLNMGVNWTLWPSLSGISLFTVASLILIWYCCCRVTPQALNYSIPMHTITSRGVEI
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: ERPA1_BURVG
Sequence: MNAVNESAATTAEMPVPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVMDKNGVQLLIDSMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA 1.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RLMG_PSEPF
Sequence: MPLLDTPFAQLDLIRQPEQQNEPLQAFDAADEYLLNHLAEQNLPIETRVLVLNDSFGALAISLSGNVQVSTSGDSFLAFQGLEKNLLRNGQAFDALRGIPASEPLVGPFDRVLIRVPKTLALLEEQLIRLQGQLAPGAQVVAAAMVKHLPRAAGDLLERYIGPVQASLAVKKARLLIATPEAKAPAVSPYPTRYRLDEPAIELLNHANVFCREGLDIGTRAFLPHLPKNLGAAGVADLGCGNGVLAIASALQNPDAHYTLVDESFMAVQSAAENWRAALGEREAIVRAGDGLAGQEAQSLDVVLCNPPFHQQQVVGDFLAWRMFQQAREALVVGGALYIVGNRHLGYHSKLARLFRGVEQVAATPKFVILKARK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_SERP5
Sequence: MIPLQHGLILAAILFVLGLTGLLVRRNLLFMLISLEVMINAAALAFIVAGSYWGQPDGQVMYILAISLAAAEASIGLALLLQLYRRRHTLNIDTVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYOE_SHEON
Sequence: MAKPLSISSQPSVNVAWRDYFEMTKPKVVALMLLTVLVGMCLAMPTILPVQPLIAGLLGIAMMAGSAAALNHLIDRRIDGLMARTYNRPLPKGRISATRALIFAAALGSLGFVILYVFTNPLTAWLTFASLIGYALIYTAYLKRATPQNIVIGGLAGAMPPLLGWTAVTNQFHGHALLLVIIIFLWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTILLAIACLLPVLVGMSGPLYFVCSSALSCGFIYKAWQLKYQDHEGLAMQVFRFSIYHLMLLFMALLLDHYLWA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 7LESS_DROVI
Sequence: MFWREDAAQQQQQQQQQQQQQQQQQQPPHPPKRLSFSFNVKIAVNVNTKMSTTHINQERSKQQTTTGSRSRSRSNSNSSVSCKGDGDRRVRRHTTRLVGLRQQLLHLGRQLNPGQFLVTGHGGISTILIANLLLLLLLSLCCNVCCRSHIEPDQNLTPTTTSPAAVAVVPMLLPLAQTHMRPQLDSDVVEKVAVWTKHVGAAPPSIAEGIAISSVVRMPPSIQTPTETVRRQEQQRQQQQQQQEAAAAAAADAAIDERIVLERVTRDCVQRCIVEEDLFLDEFGIKCEKADNSDKCYKTRCNKGCAQWYRALKEIEPCQEACASTQFYPYDMPCIGACETAQRDYWHMQRLAMARLVETTQPQLLEMTDESSTLTIKWAMQFPENYLASRPFNIQYQQVDNQSEPEWHNLADYDCDEYYVCEILEALVPYTRYKFRFELPFGESSEDVLYSPATPVYETPMEGAPISAPIIVALLALDEHHVFVHWRPGRYSNAPIEGYRVLLTSAGNTSREQLLPAQRTSCIFAQLQPLTNYTVALTMINKQGEGPSTVVSIVTKSPLEPQQLQSVLLASEHSIIWQSLEPAGETRLLYTSEPAAISDFTFSQREQRLWLLDELGQLHSQLLDETTTSAARRLRLELPSNGSSQWTPRKLSLDWLQRRLYIAAQANSSDGAEGGFELFSSNLEGGDVQMAGVQLGLVVEQLELDALNGWLFWCDADSLWRLDLSSKQQLRLTQPAGAPGRFMLEPQRWLLHVLLPQENQLLELSYDGGHKHALALSNDSWRGFAWSSDQAQLLLANETQLQLLDGQTLVPLANWSPDGGCCALLPLERRRQPLSLEPPAPRELRALLGAQGAHITWQPPAANPYQTATAAARNFSYELEVLDVASQSAYNIRNIRVPHFGLERLQADNLYQLRVRANNAAGRAGVWTAPLATRTWPLGDHRLRWATQRGSLYTTNELGGQLQPLPVQLASSPGPLALVNASVAYYVSGREQSLHCVNLLQPQLSCTDERLEHVGAVAYDWRGGLLYWTDLARDCVQRLDPFSGERELLPIFGARHLALDSAQGHLYYSSSAHLARRSLSALSTHQPELEYYHVNGLAGQISGFCLDLPQRHIYWLVAGNSALHLYRTALSAGGSQAAVPLQLLTTLPAADALPHTLQHLAPLGALLWLAADGRGAHLLRLAAQLETDTDTMRLLPEGLVEPLSAVQLLERSAGPPPPPPDEGVRPLAVPPDSVHIDEGGHWNDFRVRWQPAASGGNHSVCYKLLLEHGSERLITLELLTPFARITQLAQAPLGLRISITPHTAWRAGSTTRVQLDTPVAAPTQPRRLRVFVERQAAPLQLAPNVSALLRWDVPEEHAGSQSLQYRISCWRGSELHSELLLNQSTLEARVEHLQPEETYRFQVQAHVAATGLAAGATSHALHVSPEVQSVPRLLYANAEHIGELDLDTGHRKQLVHTASPVEHLVVLQGEQRLLWVNEHVELLSHVPGKAPAKLARMRAEVLALTVDWVQRIVYWAELDAADGGCVIYSLDLCRFDGRILQGERLWSTPRGQLLRDLVALPHARQLVWLQHDLDSRNATLQGRSLANGSALTFEGVTLPLWRLFEGSQEPLAETLNLVDHLGRLCVYHVARQLCTSSALRAQLNLLNDDIGQLAQDPGYLYALRNGSVRAYGRRRQQLEFLLELQPDEVRLLRAYNYQAYPSRRCLLLPTTAAALESTPSSCEETQCSLQLPALSAAPDCPLPVPGLNYQLNLSSSSRSAQLELRSLHSAAGLTLNISQLQPYQAYELRAQVGSYYQQQLGQEPLQLPVLTLHTAAATPSAPRNFSGRALSPSELELSWLAPLELRSASVYYTLHWQLQLEDTEEQSQEQPAQEQRVETAGVQRLTGLQPARLYQVWLQAHATPSKYNSSGRLLIRSYAPLPPLQLIELNAYGMTLAWPGTPDALSSLTLECQSLREQLQFNVAGNHTQMRLAPLQPKTRYSCRLALAYAATPGAPIYFGPSHEYETLGDAPSAPGRPQLEHIAGEIFRVSWTPALDNGSPILLYNLEALQARRTNRRRRRRRETTLSLLPWAEEPLVIEDQWLDFCNTTELSCIVRELHTRRLLLFRVRARNRPHGWGPYSEDSERIAEPFVSPEKRGSLVLAIIAPAAIVSSCVLALVLVRKLQKRRHRAKKLLQQSRPSIWSNLSALQTQQQLLAARSRTFSMSLSDADIALLPQINWNRLTLLRFLGSGAFGEVYEGQLQAEDEAQPQRVAIKSLRKGASEFAELLQEAQLMSNFKHENIVCLIGICCDTDSISLIMEHMEAGDLLSYLRAARPSSQEALSKLQLPELLSMCLDVANGCSYMEDMHFVHRDLACRNCLVSDGAAIGGRRIVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMALESLVDGLFSTQSDVWAFGVLCWEIFTLGQQPYAARNNFEVLAHVKEGGRLQQPERCPEKLYALLLQCWRSEPWERPSFKRCLSTLQALSSDLRRTEMLATDETPLVSALCAFKPDAKVRFDDAPQRLTLHLDAKDTVSTTDADTTGSPTTPTAPTTPTTTTSTIAVVSTAPSSENGQLYANEGISGL
What is the function of this protein?
Receptor for an extracellular signal required to instruct a cell to differentiate into a R7 photoreceptor.  The ligand for Sev is the Boss (Bride of Sevenless) protein.
What are the official names of this protein?
Protein sevenless.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.