PharMolix/UniProtQA huggingface dataset:
Protein: ULAC_MYCPN
Sequence: MTKLDFKAVLKQHHTVRLHQTAQDWKQAIQLCIHPLIAAKLVQPAYFDDILKSVAQYGPYFIIAENVAMPHAQNNGTVQQNCFSLVTLKEPVYFDNDPRPVRLLIGLAATSAAIHTTEALPQIAALVEDTQVVKDLLDCCDETSLFAVIDRVNLHKYLT
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIA component, Ascorbate-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_PSEAB
Sequence: MGKIIGIDLGTTNSCVAILENGNVKVIENAEGARTTPSIIAYTNDGETLVGQPAKRQAVTNPQNTLYAVKRLIGRRFEENVVQKDIQMVPYSIVKADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDIRLIDYLVDEFKKESGINLKGDPLAMQRLKEAAEKAKIELSSTQQTDVNLPYVTADASGPKHLNVKVSRAKLESLVEDLVQRTIEPCRTALKDAGLDVSDIHEVILVGGQTRMPLVQKTVAEFFGKEARKDVNPDEAVAVGAAIQGAVLAGDVKDVLLLDVTPLTLGIETLGGVMTGLIEKNTTIPTKKSQVFSTADDNQGAVTIHVLQGERKQAAQNKSLGKFDLADIPPAPRGVPQIEVTFDIDANGILHVSAKDKATGKQQSIVIKASSGLSEDEIQQMVRDAEANAEEDRKFEELAAARNQGDALVHATRKMITEAGDKATAEDKATIEKALGELEAAVKGDDKAEIEAKMNALSQASTPLAQKMYAEQAQQGEDAPQGEQAKAADDVVDAEFEEVKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MNMA_MYCBO
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHEVVGVHMALSTAPGTLRTGSRGCCSKEDAADARRVADVLGIPFYVWDFAEKFKEDVINDFVSSYARGETPNPCVRCNQQIKFAALSARAVALGFDTVATGHYARLSGGRLRRAVDRDKDQSYVLAVLTAQQLRHAAFPIGDTPKRQIRAEAARRGLAVANKPDSHDICFIPSGNTKAFLGERIGVRRGVVVDADGVVLASHDGVHGFTIGQRRGLGIAGPGPNGRPRYVTAIDADTATVHVGDVTDLDVQTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGASGLSTGGNPGA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPHN_DROAN
Sequence: MSSIDISGRYALNDLEMVSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLTVLNSRCAHKQSCSVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLNNGPPIFGNGSGLIHPPGSPGAAPPPPRLPTLPGVVGISGNGGLFNVPPPHTVTHSTPSSSTVPGRMKGVATSTTTTKNPAGRHDGLPPPPQLHHHHTHHGEEAAPPTKPSSKLPSAGNATAPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPVTASNGSPASGNNSVVRTINNINMNAAGMSGADDESKLFCGPTHARNLFWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRLPDSGYDEYDDDPSSTTPAPSGGDCLHNSSSCDPPVSMAHKVNQRLRNFEPTWHPMTPDLTQCRSLWLNNLELRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMLHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIPPSVIFPDSDQWPLSSDRIELPRAALLDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILANDSSDSNTGEIQQRIRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRVFIYISIAICVVFIVIALLTLKLFNGVFVKSARTTIYTSIYVCLLAIELLFLLGIEQTETSIFCGFITVFLHCAILSGAAWFCYEAFHSYYTLTSDELLVEVDQTPKVNWYYLLSYGLSVSVVAISVAINPSTYTQNDYCVLMEANILFYATFVAPVLIFFVAAIGYTFLSWIIMCRKSCTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKTDEDTTTIYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVAGGGPAAGTLCSVNTSKKPKLPLGVSEEVHGEQQQHQQAMGVPAPEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQTPQQPLAGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQALGESYYHQPDYYSWKQPPQGGLKSQREYYNNAGVAASSPQQAHEVFYWTQKPNSQHGKKKRGGAVPASPSGSLHSRTAAASQVLFYPSYKKTKQGQPSGYPHYAEALDPPHSAGAAFYQQQQQMRRQQQQQQQQQQQQLSSDEEQAEQHAHLLHLQHQQQHQRRVGGQQQLPAPPPHMAHFQQEFMQRQFRNKTSNCDLAMGGDTYHNQGSEGGADVCPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNSMRAAITAGGSRYGGGSLSGGSVSSRSQQQQLQKQQKQQQQQQQRSARRCTADDDDDDDEEEDDEATAAEQLHDSVCDDDDEEEDSDLDDDAHKLPPQSDERMRRLMAMQDEDFKRRFQRQQRKNGASIDYGALPPGVAPGAGSAGPHPDHNRAVFGVSGGVGEGSMRGAYRQQQQQQQQQLNAKSPSARLAVNELFGHGNAGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNLQPHPHPLTHQHPHPPQHQQRHLSAMLDENNTVRCYLEPLAK
What are the official names of this protein?
Latrophilin Cirl.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVD_ECO55
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y4722_DESHD
Sequence: MLSKQVRLLVITGLSGAGKTQALQSLEDQGYFCVDNLPPSLILKFAELCTQSQGKVTRAAIVCDLRGGEFFSSLAEALGDLHREGFHYEILFLEASDEVLVGRYKESRRRHPLSPSGGILEGIQMERQMLTELRGVAHKIMDTSNLSSQQLRHQVAESFGNEQASGHLAVSVVSFGFKYAIPLDVDLLIDVRFLPNPFYVAELRPLTGEHPQVQDYIFSNPVAQEFVDKYLGLLEFILPYYVKEGKRHLVIGVGCTGGQHRSVAIAERIGLFLQERSYMMSVKHRDAARNRKGDKSK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Dhaf_4722.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CARB_MYCTO
Sequence: MPRRTDLHHVLVIGSGPIVIGQACEFDYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVERVIAQQAERGNKIDALLATLGGQTALNTAVALYESGVLEKYGVELIGADFDAIQRGEDRQRFKDIVAKAGGESARSRVCFTMAEVRETVAELGLPVVVRPSFTMGGLGSGIAYSTDEVDRMAGAGLAASPSANVLIEESIYGWKEFELELMRDGHDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAILREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALGKVMRSLETTRAGFWTAPDPDGGIEEALTRLRTPAEGRLYDIELALRLGATVERVAEASGVDPWFIAQINELVNLRNELVAAPVLNAELLRRAKHSGLSDHQIASLRPELAGEAGVRSLRVRLGIHPVYKTVDTCAAEFEAQTPYHYSSYELDPAAETEVAPQTERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFEPLTFEDVLEVYHAEMESGSGGPGVAGVIVQLGGQTPLGLAHRLADAGVPIVGTPPEAIDLAEDRGAFGDLLSAAGLPAPKYGTATTFAQARRIAEEIGYPVLVRPSYVLGGRGMEIVYDEETLQGYITRATQLSPEHPVLVDRFLEDAVEIDVDALCDGAEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIAKVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGATIAQLRAEGLLAVTGDGAHAARNAPIAVKEAVLPFHRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQGTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDDVRKHFEPAQPGRPTMSAVDAIRAGEVNMVINTPYGNSGPRIDGYEIRSAAVAGNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHRVIGGVER
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: NACHO_XENTR
Sequence: MASPRTVTIVALSVTLGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVKALPALKKIGISSVFLRKAIGSLELACGIVLTLVPGRPKDVANFILLLLVLIVLFFHQLVGDPLKRYAHALVFGILLTCRLLVSRQPEEEFPEKKLSRGNNGAHSREPIKMKVS
What is the function of this protein?
Molecular chaperone which mediates the proper assembly and functional expression of the nicotinic acetylcholine receptors (nAChRs) throughout the brain (By similarity).  Essential for the proper folding, assembly, function and surface trafficking of alpha-7 (CHRNA7), alpha-4-beta-2, alpha-3-beta-2 and alpha-3-beta-4 receptors (By similarity).
What are the official names of this protein?
Novel acetylcholine receptor chaperone, Transmembrane protein 35A.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum membrane; Multi- pass membrane protein. Note=Shedding may lead to a soluble peptide.
Protein: RL7_SALPB
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RUXX_METAR
Sequence: MSQRPLDVLNEALNSPVIVRLKGGREFRGELQGYDMHMNLVLDNAEELKENEASRKLGTIIVRGDTVVYVSP
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: RF2_ARTS2
Sequence: MAQIDFSAEIRALRATYSSIENVSNVEELKEDIAELSERAGEPNLWDDPAAAQKITSRLSHRQSELERLNTLVSRIDDLEVLVELGQDEDDADSMGEAAAELESIRKSLKDLEVVTLLSGEFDEREAVVTIRAGAGGVDAADFAEMLLRMYLRWAERHGYPTTIMDTSYAEEAGLKSATFEVNAPYAYGTLSVEAGTHRLVRISPFDNQGRRQTSFAAVEVIPLIEQTDSIDIPDNEIRVDVFRSSGPGGQSVNTTDSAVRLTHIPTGTVVSMQNEKSQLQNRAAALRVLQSRLLLLKKEQEDAEKKAFAGDVKASWGDQMRSYVLNPYQMVKDLRTEHEVGNTSAVFDGEIDDFIDAGIRWRTDNRNAAN
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y409_MYCGE
Sequence: MENINYQILKRSEKKLLKLFFEYFKHVINAHETLNQLLCEDNLEKRKELIKTIYEMEDQSNRSEFKLINESIWTISKNSPLASHLRLTITIIMSSRDLERICDYANNLTKFIEHYLHLDIKIFNNLVTLHQSALNNLKKTFESLQDKEKPLTLQFENATKTIIEFEHQYRLVLTKYYETINKNEVTERIFLIDLVASVKHIERINDYCYNIIKSFLFIKNPEIFN
What are the official names of this protein?
Uncharacterized protein MG409.
Protein: RECN_ECOLI
Sequence: MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGLCLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMTARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLANSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQIAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQQLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQFTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKETDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA
What is the function of this protein?
May be involved in recombinational repair of damaged DNA.
What are the official names of this protein?
DNA repair protein RecN, Recombination protein N.
What is the protein family that this protein belongs to?
Belongs to the RecN family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In 70% of cell localizes to discrete nucleoid foci (probable DNA damage sites) upon treatment with mitomycin C (MMC) for 2 hours.
Protein: EIF3A_DROSE
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVSQYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERMDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIVRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKERDTWRPRGGDRPSASAGGSSEWRRAAPAVSERNDRGGERIERGGDRVERGGERIERGGERIERGGDRDRKDNEGADSSWRVRREPDTQRAAAPKDSGAPQSRDDKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRNDGPRRTDEPQRESGGNWRDAPRHADRENRRPAGERRDRDVRETRGDQRGSAPKEAASGGGGGNWRNAPATREEKPAAKRDQAQEKENKAGDDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_THEP1
Sequence: MEIEAVEKEAIEKLSKISNVQELESFRIEFLGKKGKITGLMKNLKNLPPEERPAYGKRVNELREKIEKLFEEKRQQIQRILEQEKMEKMRIDVTVPGARRKLGHSHPVLKVMEEIERIFVSMGFDVVEGPEIETTWHNFDALNTPEWHPARDEHDSFYITDDLLLRTHTSPVQIRTMLERKPPIAIISPGKVYRRDYDATHLPMFHQVEGLHVDRDLSVAHLKFTLEEFARRMFGEGAKVRLRPSFFPFTEPSFEVDVYLSGYGWLEILGAGMVDPNVFLNVGYDPEEWTGYAFGMGVERIAMLKYGITDIREFVRNDVRFLSSY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_GEOSW
Sequence: MLRLDLQFFASKKGVGSTKNGRDSIAKRLGAKRADGQFVTGGSILYRQRGTKIHPGLNVGRGGDDTLYAKIDGIVRFERLGRDRKRVSVYPVSKEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ILVD_METTP
Sequence: MRSDITKSGPERAPHRALLKAMGITDDEIKRPFIGVANSANEFVPGHIHLDRIAEAVKAGIRIAGGVPFEFQTIGVCDGIAMGHGGMRYSLPSREIIEDSIEIMAQAHQLDGLVLIPTCDKIVPGHLMAAGRLDLPTIVVTGGPMLPGFACDRELDLINVFEEWQKGGESLSILEDLACPGAGSCAGLFTANSMACMAEALGLSLPGCATAHAVDAKKMRIAKLSGMMIVELVKRGLTARKIVSRESFENAVRVDMAIGGSTNTALHLPAIAAEFDIDLELDVFDRLSRETPHLVNLRPGGPHHMLDLDRAGGVQAVMHRLSSKLDLSVLTVTGKTLGAVLAEFKPVNPKANAEVIATLERPVHPEGGIAILKGSLAPEGSVVKQTAVSKKMLVHKGPAVVYDSEEESMKGILSGEVKAGDVVVIRYEGPKGGPGMRETLAPTSAIAGAGLSESVALITDGRFSGGTRGPCIGHVSPEAAVGGPIALVENGDMISIDIPNRRLDLLVDEGVLERRRASWRPPEPRVRGGVLDRYRKSVTSASKGGVLR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HOLD_ECOLI
Sequence: MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVANDLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSHCNSWRLGTDEPLSLEGAQVASPALTDLRANPTARAALWQQICTYEHDFFPRND
What is the function of this protein?
Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form the DNA replication pre-initiation complex (PubMed:2040637).  DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The exact function of the psi subunit is unknown.
What are the official names of this protein?
DNA polymerase III subunit psi.
Protein: STAT_HUMAN
Sequence: MKFLVFAFILALMVSMIGADSSEEKFLRRIGRFGYGYGPYQPVPEQPLYPQPYQPQYQQYTF
What is the function of this protein?
Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts.  It also modulates hydroxyapatite crystal formation on the tooth surface.
What are the official names of this protein?
Statherin.
What is the protein family that this protein belongs to?
Belongs to the histatin/statherin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_METS3
Sequence: MDSYSIIIKPHVTEKTMNLIDKNNEITFVVKRDANKGQIKRAFEELYEEKVARVTTHITPRGNKVAFIKLVEEEMAEELAVKIGVF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YGAQ_ECOLI
Sequence: MFSIKPGPRNLPIDNPTLLSWNITDGDLNSKLNTLEYLNCITNIINSCGVYPQGLKDREIISTFHAEKVINDLLKNDYKISLSPDTTYRELNKAAQRSITAPDRIGERKTWVYQRDTMIERGDNSGVYQYGRAEHFTHIISDKPSPKDKYVAYAINIPDYELAADVYNINVTSPSGQQETFKILINLEHLRQTLERKSLTAVQKSQCEIITPKKPGEAILHAFNATYQQIRENMSEFARCHYGYIQIPPVTTFRADGPETPEEEKGYWFHAYQPEDLCTIHNPMGDLQDFIALVKDAKKFGIDIIPDYTFNFMGIGGSGKNDLDYPSADIRAKISKDIEGGIPGYWQGQVLIPFIKDPVTKERKQIHPEDIHLTAKDFEASKDNISKDEWENLHALKEKRLNGMPKTTPKSDQVIMLQNQYVREMRKYGVRGLRYDAAKHSKHEQIERSITPPLKNYNERLHNTNLFNPKYHKKAVMNYMEYLVTCQLDEQQMSSLLYERDDLSAIDFSLLMKTIKAFSFGGDLQTLASKPGSTISSIPSERRILININHDFPNNGNLFNDFLFNHQQDEQLAMAYIAALPFSRPLVYWDGQVLKSTTEIKNYDGSTRVGGEAWLNKGCSTYQQLYNEFHALYIDKAGIWSAFEGVSATKNVLAFSRGDSVNINHSPHDGLVIINKGNEEVEGTWPNKLQPGIYKNMGSNSVNIIINNTRKIIPPGKVFTLRGGTLNINIPGRSALLLGKTGEPPNYLYL
What are the official names of this protein?
Putative uncharacterized protein YgaQ.
Protein: Y2816_PSEP1
Sequence: MIISTTSQLEGRPIAEYLGVVSSESVQGINFVRDFFTRFRDFFGGRSQTLESALREAREQATEELKARARQLQADAVVGVDFEISMPSVQGGMVVVFATGTAVRLK
What are the official names of this protein?
UPF0145 protein Pput_2816.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: GATC_PSEPW
Sequence: MALERCDVEKIAHLARLGLNEGELPRITDALNSILGLVDQMQAVDTTGIEPLAHPLEASQRLRPDQVTESNQRDAYQAIAPKTESGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ZNF16_PANPA
Sequence: MPSLRTRREEAEMELSAPGPSPWTPAPQARVSDAPAVTHPGSAACGTPCCSDTELEAICPHYQQPDCDTRTEDKEFLHKEDIHEDLESQAEISENYAGDVFQVPKLGDLCDDVSERDWGVPEGRRLPQSLSQEGDFTPAAMGLLRGPLGEKDLDCNGFDSCFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGVPTAESPLICNECGKTFRGNPDLIQRQIVHTGEASFMCDDCGKTFSQNSVLKNRHXSHMSEKAFRGHSDFSRHQSHHSSERPYTCTECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKAFSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIHTRE
What is the function of this protein?
Acts as a transcriptional activator.  Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase.  Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively.  Also plays a role as an inhibitor of cell apoptosis (By similarity).
What are the official names of this protein?
Zinc finger protein 16.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVC_CYTH3
Sequence: MANYFNTLSLREKLDQLGVCEFMDRSEFSDGVAALKGKKIVIVGCGAQGLNQGLNLRDSGLDVSYTLRKEAIDSKRQSFLNASENGFKVGTYEELIPTADLVINLTPDKQHTAVVSAVMPLMKKGSTLSYSHGFNIVEEGMQIRKDITVIMVAPKSPGSEVREEYKRGFGVPTLIAVHPENDPEGKGWDYAKAYCVGTGGDRAGVLKSSFVAEVKSDLMGEQTILCGLLQTGSILCFDKMVEKGIDKGYASKLIQYGWEVITESLKHGGISGMMDRLSNPAKIKAFQVSEELKDIMRPLFRKHQDDIISGEFSRIMMEDWANGDKNLLTWRAATGETAFEKTPAGDVKIAEQEYYDNGLLMVAMVRAGVELAFETMTESGIIDESAYYESLHETPLIANTIARKKLFEMNRVISDTAEYGCYLFDHACKPLLANFMKTVDTDIIGKNFNAGKDNGVDNQMLIAVNEVLRSHPIEIVGAELREAMTEMKAIVS
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SECA_PARD8
Sequence: MGFNEFMTKLFGNKSQRDLKEITPYVDKVKAVYPSIKALSNDELRAKTDEIKQRIQDYVAEEKAQVEELRKGIEDKELEEREAIWAEVDKIEKAITDKMEVVLEQSLPEVFAIMKDTARRFAENEEVVVTANQFDRDLAARFDFVRIEDDKAIYANHWKAGGNEITWDMIHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTRNGVHVVTVNDYLSKRDSEWMGPLYMFHGLSVDCIDKHQPNSEARRKAYEADITFGTNNEFGFDYLRDNMAISPKDLVQRKHNYSIVDEVDSVLIDDARTPLIISGPIPRGEEQLFEQFRPNVEVVVNAQKDLCSKLLIEAKKKMASDDQKVVEEGSILLYRSFKGYPRNKALIKFLSEQGVKAQMLKTEEYFMSENMRHMHEATDELYFVIDEKNNSIELTDKGIDLLTGKTDDPTFFVLPDITSQLSQLENMTGTEEEKQAQKDEILANYSVKSERVHTINQLLKAYTLFEKDDEYVVMDNKVMIVDEQTGRIMDGRRYSDGLHQAIEAKERVKVEAATQTFATITLQNYFRMYHKLSGMTGTAETEAGEFWDIYKLDVVVIPTNRPIARNDMNDRIYKTKREKYNAVIEEIVQLTEAGRPVLVGTTSVEISELLSRMLTMRKIQHNVLNAKLHQKEAEIVALAGQKSTVTIATNMAGRGTDIKLSKDVKDAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFFVSLEDDLMRLFASEKIAGLMDKLGFKEGEVLEHNMLSKSVERAQKKVEENNFGIRKRLLEYDDVMNSQRNVIYTRRRHALMGERIGLDVLNTIYDTSTAIADQHAEDFEGFKLELFKTFAMESPFTEDEFKSMKPEQLVEKLFEEALKTYKRRMERMTQVAHPVIKQVYENQGAMYENIMIPITDGKRMYNVSCNLKEAYDTECKAIVKSFQKSIVLHMIDEGWKEHLREMDELRHSVQNASYENKDPLLIYKLESYNLFKTMVDNMNRKTAAILMRGQIPVREEPTEEQRQAMQARQAAVAQQAAQAIAEERARQRIAVQEAAPEKHEDMSRYRTEKTDLSGNNTQAEAPQPKQAPVRAEKRVGRNDPCPCGSGKKYKNCHGQGL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.