PharMolix/UniProtQA huggingface dataset:
Protein: CYAS_METPS
Sequence: MGTYTLECAGCRHTIPDNYTLRCECGAGLIRARYTARQISPRDLPGMWRYYDWLPTRGHLDTPGAPVTFKSQGLSKELGLKELYISFNGYWPEMGARMDTCSFKELEAPPTIVRAREHGGRAMVLASVGNTARAFAYLSTLTGFPVVIVVPRKSAHNLWIPGREPGDSIKLITMEEGNDYSDAIRLSERIAGIEGVMPEGGARNVARRDGMGVTMLDAAVTMKRMPDDYFQAIGSGTGGIAAWEAALRLRDDGRFGDRLPKLHLAQNLPFAPMYYAWKAGRRDIIPELDMPEAKKQIEAMYTDILSNRNPPYGVTGGVYDALIDTQGDMYAVTNDEAIRAKRIFEKAEGIDILPPAAVAVAALLQACDRGLEKKRTVLLNITGGGLERLRKEVSMSMVKPCLNVEGPEVPLENITKAIQWQTLSKKS
What is the function of this protein?
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
What are the official names of this protein?
Cysteate synthase, CS, Cya synthase.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family. Cysteate synthase subfamily.
Protein: DGOD_KLEP7
Sequence: MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARINDLWQVMYRGGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAVDAAVNTVAQIREAFGNEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSRFEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVDFVSHNAVFQEQSMGIHYNKGAELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIELSKNAPDWRNPLWRYEDGSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: CYB_HYPTE
Sequence: MANLRKTHPLLKIANDALIDLPAPSNISVWWNFGSLLGLCLAAQILTGLFLAMHYTSDIATAFSSVAHICRDVNYGWLIRDMHANGASFFFICIYLHIGRGLYYGSYLYKETWNVGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNSLVQWLWGGFSVDNATLTRFFAFHFLLPFIIAAMTMIHLIFLHETGSTNPAGLNSDTDKISFHPYFSYKDLLGFAILLIALIALALFSPNLLGDPDNLTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLVPVLHTSKLRALTFRPLTQFLFWLLIADVAILTWIGGMPVEHPFIIIGQVASFLYFFIFLILLPTAGLAENKMFA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYFA_NOCFA
Sequence: MDLSEEALAAAAADAEKAFAAAADLDALAVAKTEHLGGKAPLALAQRALGALPKEEKKDAGKRVNVARGRVAEAFEARRAVLLAERDAAVLVAEAIDVTLPARRQQVGARHPITVISERIADVFVAMGWEVAEGPEVETEHFNFDALNFLPDHPARTMQDTFHIAPEGSRQVLRTHTSPVQVRSMLERDLPIYVVCPGRTFRTDELDATHTPVFSQVEGLAVDKGLTMAHLRGTLDAFARALFGPETRTRMRPNYFPFTEPSAEVDVWFPDKKGGAGWVEWGGCGMVNPKVLIASGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDIVEGDVRFTLPFGIQS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_DICDI
Sequence: MSEQIKKRTFKKFTYSGVALESLLDLKEEQLISLLRCRARRKLRRETPIKHVNFLKKCRASKAAVTQVGEKPALVKTHARNILIVPEMIGSVIGIYNGKVFNQVEVKPEMIGHYTGEFSLSYKSVNHGRPGIGATHSSRFIPLK
What are the official names of this protein?
40S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: VE1_HPV70
Sequence: MANCEGTDGDGSGCNGWFLVQAIVDKQTGDTVSEDEDENATDTGSDLADFIDDTTDICVQAERETAQVLYNMQEAQRDAQSVRALKRKYGGSNLNKSPCAKPPGVHREQRVTLQELPVNICNKQARTNVYSVPDSGYGNMEVETAEVEVTVVNNTNGEEEGENGGENGGSIREECSSVDSAIDSENQDPQSPTAQLKTVLQANNQKAILLSQFKHTYGLAFNDLVRTFKSDKTICTDWVAAICGVNPTIAEGFKTLIQPYALYTHIQCLDTKYGVYILLLIRYKCGKNRITVGKGLSKLLHVPESCMLIEPPKLRSPVAALYWYRTGMSNISEVSGTTPEWIQRLTVIQHGIDDSVFDLSDMVQWAFDNDVTEDSDIAYGYALLADSNSNAAAFLKSNCQAKYVRDCATMCRHYKRAQKKQMTMAQWIRFRCDKCDDGGDWRPIVQFLRYQGVEFITFLCAFKEFLKGTPKKNCIVIQGPPNTGKSYFCMSLMHFLQGTVISYVNSTSHFWLEPLADAKVAMLDDATGTCWSYFDTYMRNALDGNPISLDRKHRHLIQIKCPPILITSNTNPVEENRWPYLTSRLTVFTFPNAFPFDQNRNPVYTINNKNWKSFFQKTWCKLDLQQDEDEGDNDGNTIPTFKCVTGENTRTL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL27_PSEA8
Sequence: MAHKKAGGSTRNGRDSESKRLGVKLFGGQAVKAGNILVRQRGTKFHAGYGVGLGKDHTLFAKVDGVVKFETKGAFGRKYVSIVAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SYDND_BACC1
Sequence: MAERTHACGKVTVEAVGQTVQLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPETSKEALEVAETIRSEYVLHVEGTVVERGEGAINDNMATGRIEVQATKVNVLNAAKTTPIIIADDTDASEDVRLKYRYLDLRRPVMFNTFKMRHDVTKTIRNFLDTEEFLEVETPILTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMVGGFERYYQVARCFRDEDLRADRQPEFTQIDIEASFLTQEEILDMMERMMTKVMKDAKGVEISAPFPRMTYADAMARYGSDKPDTRFEMELTDLSEFAAGCGFKVFTSAVESGGQVKAINAKGAASKYSRKDIDALTEFVKVYGAKGLAWLKVEEDGLKGPIAKFFGEEDANVLMTTLEATAGDLLLFVADKKSVVADSLGALRLRLGKELELIDESKYNFLWVTDWPLLEYDEDADRYFAAHHPFTMPFREDVELLETAPEKARAQAYDLVLNGYELGGGSLRIYERDVQEKMFKALGFSQEEAQEQFGFLLEAFEYGTPPHGGIALGLDRLVMLLAGRTNLRDTIAFPKTASASCLLTEAPSPVAEAQLEELNLKLSLKEEK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_AGRRK
Sequence: MTLSNTIQITPELIAAHGLKPDEYQRILDLIGREPSFTELGIFSAMWNEHCSYKSSKKWLRTLPTKGPRVIQGPGENAGVVDIDDGDCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPIAAMNALRFGEPDHPKTRHLVSGVVAGVGGYGNSFGVPTVGGEVEFDARYNGNILVNAFAAGLAKSNAIFLSEAKGVGLPVVYLGAKTGRDGVGGATMASAEFDESIEEKRPTVQVGDPFTEKCLLEACLELMQTGAVIAIQDMGAAGLTCSAVEMGAKGDLGIELDLDKVPVREEQMTAYEMMLSESQERMLMVLQPEKEAVAKAIFVKWGLDFAIVGKTTDDLRFRVIHQGEEVANLPIKDLGDQAPEYDRPWREADKRAALPANLVAAPEDYGQTLLSLVGSANQSSRRWVYEQYDTLIQGNSLQLPGGDAGVVRVEGHPTKALAFSSDVTPRYVEADPFEGGKQAVAECWRNITATGAEPLAATDNLNFGNPEKPEIMGQLVGAIKGIGEACRALDFPIVSGNVSLYNETNGVGILPTPTIAGVGLLPDWQAMARIGSASEGDRIIMIGVDGSHLGSSIYLRDILGSTDGPAPEVDLFAERRNGDFVRSAIRNGQVTACHDISSGGLGLALAEMAMASGKGLNIDLGECKGLSHALLFGEDQARYVIAVPADVADFVCINAESAGVPFRRLGTVEGDALAIDGLLSVSVQQLRQAHESWFPAFMDGSALAAAE
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2312_MYCTO
Sequence: MMKEIELHLVDAAAPSGEIAIKDLAALATALQELTTRISRDPINTPGPGRTKQFMEELSQLASAPGPDIDGGIDLTDDEFQAFLQAARS
What are the official names of this protein?
Uncharacterized protein MT2374.
Protein: GSA_JANMA
Sequence: MSSKNDQLFARAQLSTPGGVNSPVRAFRSVGGTPRFITKAEGPYFWDADDRRYIDYIGSWGPAIVGHAHPDVVKAVQDAATRGLSFGAPTEAEIEMAELICRLVPSIEQVRLVSSGTEAAMSALRLARGATGRDKIIKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPEDFAKHTLVLDYNDPAQLENVFKEMGDSIACVIVEPVAGNMNLLPATPEFLQTMRRVCTQYGAVMILDEVMSGFRVALGGAQSLYGITPDLTVLGKVIGGGLPVAAFGGRADIMRHLAPLGGVYQAGTLSGNPVTVAAGMATLKLIQAPGFYENLTAQTTKLVHGFSAAAREADIAFCANSVGGMFGLYFASEVPVSYDTMMKCDKTRFNAFFHAMLDAGVYLAPSAFEAGFVSAQHDDAVIDSSIKAARAAFAQLADDCDD
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_LEGPC
Sequence: MSNNFKRTDRIAEMIQRKLALIIPQEIKDPRLKGFVTISAVKVAADLGHAKIYFTVLNEDKSVVTNILNGAASYLRSALARSITLRTVPQLHFIYDESIEYGQRLSRLIDEVNPPDSSSDDNN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBK1_YEAST
Sequence: MYNSSTNHHEGAPTSGHGYYMSQQQDQQHQQQQQYANEMNPYQQIPRPPAAGFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMGGLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSSSSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQQEQENVQVQQQLSQAQQQNSRQQQQQLQYQQQQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKLKIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFHTVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSISLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPDDIHISYEAEDLIRRLLTHADQRLGRHGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMTKQGGSAPVKEDLPFIGYTYSRFDYLTRKNAL
What is the function of this protein?
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase CBK1, Cell wall biosynthesis kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
Protein: RUVC_EHRRG
Sequence: MNIIGIDPSLNSTGWAILSVNDNNYNEIRLVNNGSILTSNKKTIGERLNKIYSELLNILNSYKVDTASMEEIFINKNPKSSTLLCYARGILLLTLDVACIPLFEYSANRVKKSITGNGHAKKEQVCFMIENILNIKCYGTYDISDAIAVAICHIYSIKAF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PA60H_BISBO
Sequence: RGSNLTTHPLRNIKDLVVYM
What are the official names of this protein?
Pregnancy-associated glycoprotein 60H, EbPAG-H 60 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TRUA_LISMO
Sequence: MTRYKAIISYDGSGFYGYQVQPNTRTVQAEIEKALTKMHKGKTVRVTASGRTDTGVHAKGQVIHFDSELDITAEKFQKALQVMTPFDISFLTVEEVPDDFHARFGTVGKEYRYVVKRTKIFDPFSRNFALHYPYELDISKMKLASKRLIGEHDFTSFCSARTERDSKVRTLYSIDFYEEDDETLVIAFQGNGFLYNMVRILTGTLLDAGQGRISPDDISEALLARDRQKLISKTAPPQGLYLWRVDYE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PTH_STRP4
Sequence: MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOHH_MOUSE
Sequence: MVTEQEIEAIGKTLVDPKQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDARAIPVLADVLQDTSQEPMVRHEAGEALGAIGNPEVLGLLKQYSTDPVVEVAETCQLAVGRLEWLQQHPGEATCAGPYLSVDPAPPAAEQDVGRLREALLDEARPLFERYRAMFALRNVGGKEAALALAEGLQCGSALFRHEVGYVLGQLQHEAAVPGLAATLARTTESPMVRHECAEALGAIARPACLAALREHIEDPEQVVRESCEVALDMYEYESSQDFQYADGLERLRPPP
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: PUR4_MYXXD
Sequence: MHTLRGAPALSDFRLAKLLAQCRERVPSVSSIYAEFVHLIDAPAPLSEADLATLGRLLDYGPRVATGARIGSLLLVLPRPGTISPWSSKATDIVHNCGLGERVRRMERGTAFFIAGPDGQALQDAELERLKPVLHDRMTQAVVGRLEDAAILFAGHTPRPFTTVDVLGGGRAALVTANRELGLALADDEMDYLVARFTELKRNPTDVELMMFAQANSEHCRHKIFNASWTIDGKPQERSLFQAIKNTYVQHKEGVLGAYKDNAAVIEGFEVDRFFPSPESGEWGSVREPAHIMIKVETHNHPTAISPYPGAATGAGGEIRDEGATGRGARPKAGLTGFSVSHLRIPGFEQPWEQPYGKPDRIVSALDIMVDGPLGGAAFNNEFGRPNLTGYFRSYEVQVPTPGGVEVRGYHKPIMIAGGLGNIRASHVQKGRLQPGDKLIVLGGPAMLIGLGGGAASSMAQGASAADLDFASVQRDNAEMERRCQEVIDSCWALGDKNPIRSIHDVGAGGLSNAVPELAHDNDLGGRLELRAVPNAEPGMSPVEIWCNEAQERYVLGVAPEDLARFAALCERERAPFSVLGDATAEQTLKLGDTQFGNAPIDLPMDVLFGKPPRMHRDVTSRPVSFAPLTLDGSLALLAERVLSHPTVADKSFLITIGDRTVSGLSSRDQMVGPWQVPVADCAVTLSTVTSTTGEAMAMGERTPLALIDAAASARMAVGEALTNIAAARIGKLSDVKLSANWMAAAGSPGEDASLYAAVHAVGMELCPALGLTIPVGKDSMSMRTVWEEGGARKAVTSPVSLIISAFAPVLDVRKSLTPQLVDVADDTRLLFIDLARGKQRLGGSVVAHVHGQVGPESPDVEDPALLRGFFAAVQALSESGSLLAYHDRSDGGLWATLCEMAFAGRCGLDVDLAPLGGDVTAALFNEELGAVVQVRASDVARVREVLAQHGLSRDVHELGRPVTALQVRVRHGGDTLMAEDTLALRRTWSRVSYEMQKLRDNPICADQESAARSDASDPGLSPKLTFDPAQDVAAPFIAKGARPRVAVLREQGVNSQQEMAAAFTRAGFAAVDVHMSDILSGRVSLEGFKGVLACGGFSYGDVLGAGGGWAKSILFNPRARDAFAAFFARPDSFGLGVCNGCQMMSQLKDIIPGAEHFPRFVRNASEQYEARLSLVEVSKTPSLFYQGMEGSRMLIVTSHGEGRAEFPSVEDAARVNGLGLVTTRWVDNHGRVAESYPANPNGSPHGIAGLTTRDGRFTITMPHPERVHRSVQHSWRPREWGDDGPWMRMFRNARVWLG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 7B2_PIG
Sequence: MVSTMLSGLVLWLTFGWTPALAYSPRTPDRVSETDIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPFGNIPNIVAELTGDNTPKDFSEDQGYPDPPNPCPIGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWNKKLLYEKMKGGQRRKRRSVNPYLQGQRLDNVVAKKSVPHFSDEDKDPE
What is the function of this protein?
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway.  Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated.  Also required for cleavage of PCSK2 but does not appear to be involved in its folding.  Plays a role in regulating pituitary hormone secretion.  The C-terminal peptide inhibits PCSK2 in vitro.
What are the official names of this protein?
Neuroendocrine protein 7B2, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I.
What is the protein family that this protein belongs to?
Belongs to the 7B2 family.
What are the subcellular locations of this protein?
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Protein: SPAN1_BPP22
Sequence: MSRIKAIIASVIICIIVCLSWAVNHYRDNAITYKEQRDKATSIIADMQKRQRDVAELDARYTKELADANATIETLRADVSAGRKRLQVSATCPKSTTGASGMGDGESPRLTADAELNYYRLRSGIDRITAQVNYLQEYIRSQCLK
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is due to local fusion between the inner and outer membrane performed by the spanin complex.
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin, Gene product 15, Gp15, Lysis protein Rz.
What is the protein family that this protein belongs to?
Belongs to the Lambdavirus i-spanin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: UPP_CLOK5
Sequence: MSKVTQITHPLILHKLALIRDKRTGSKDFRELVEEVAMLMAYEVTRNLQTEEVEIETPICNTTCKMLSGKKVAVVPILRAGLGMVGGMLKLIPAAKVGHIGLYRDETTLKPVEYFCKLPQDIGEREVIVTDPMLATGGSAIDAITMLKQKGAKNIRLMCLIAAEDGIKSVTEAHPDVDIYTAAIDKELNKNGYIVPGLGDAGDRLYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SURE_PARL1
Sequence: MAKSGTKSLRILVTNDDGIHAPGLKVLEKIAHKLSRDVWVVAPEDEQSGSAHSLSLANPLRVRKLTARKYAVRGTPSDCVLMAVRHILKDEQPDLVVSGINRGQNIADDVTYSGTIAAAMEGTQLGIPSIALSQAFGFSGSANVKWSTAEHFAPDILKKLIAAGWPEEVLININFPDVVPGSVTGIEVTRQGKRDQSLVRVEERIDARNNPYYWLGFERILSNPPQGTDLRAIYESRISITPLHMDLTHQKTAKALNDALGTLAQPKRRPRSASRKK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRA20_CAEEL
Sequence: MNKTAEELVESLRCASEGLTNALTSITVKVSFVFLATVILLSYYFAVLAIRALWNNNIFSNSTRLILIVCLLNSVVHQSTMMEIRIRQVYRSFVYSSEPCRLPFHFTDCEVELYFYYLTNYFSTYSVFSLTFDRLISYFFPKCYISYPYQVSISLLIIQLVFTLGTYYFGLYGVPKLGYVPICNYAPRLATNFVKINDFRTTIMVFCIIVTIFIYYLNVKSEKQIKRTSYSLGEQYLARENVATSQSVCILIVLQFVCISVSSFGVNYIKSIKSTLSDEEYNKIAPFVVGVTYANLCLPLVIYFKTKLTIRKRRIRIGVMTSVYGDVGEHINRLKKSWE
What are the official names of this protein?
Serpentine receptor class alpha-20, Protein sra-20.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: INS_ONCKE
Sequence: MAFWLQAASLLVLLALSPGVDAAAAQHLCGSHLVDALYLVCGEKGFFYTPKRDVDPLIGFLSPKSAKENEEYPFKDQTEMMVKRGIVEQCCHKPCNIFDLQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YOJ3_CAEEL
Sequence: MGIIISLVAPTVSSTISSRLMIGPENNEKDAKNSDRTKYDNLAMLGRSPEQKEHVNPFEKAPVARPTRNTVDSQMMLGPPKKANDQSASDCSIYDNLVVPMSELGPTPGNKPSPNPIEGAPMIRPPQDTVSRAPDNSIYDTLQMTPEVDWSKKMTMKSMKKTGK
What are the official names of this protein?
Uncharacterized protein ZK353.3.