PharMolix/UniProtQA huggingface dataset:
Protein: SYM_DICNV
Sequence: MSVRRIFVSSALPYANGSIHLGHMVEHIQTDIWVRFQQLRGHECYYVCADDAHGTAIMLHAEKKGVTPEVLLDEVRAEHISDFQGFLINHHHYHTTHSDENRQLTNEIYQTLKSKGYILKKEISQLFDPEKNIFLPDRFIKGICPKCQAKDQYGDNCEVCGSTYAPTDLIQPYSVLSGATPIMKKSEHFFFDLPQFTDFLKDWLQRADLQPAMRHKLAEWFEAGLQPWDISRDAPYWGFTIPEAKDKYFYVWLDAPVGYLGSFQAFCQQHQHVSFDDFWRDDNKTERYHFIGKDIAYFHMLFWPAMLEGAGLQKPTGVFCHGFLTVNGEKMSKSRGTFIKARTYLKHLRPEYLRYYIASKLSAKVEDIDLNLNDFRQKVNSDLVGKLINLASRSAPFLQRFADNTTVSAFSDSALLEQLRGKSETIARDYEQREFGQAVREVMALADAVNAYVDETKPWILAKETGKAAEIAQIASVVLEAFRLLIIYLKPVLPKVAADAEAFLKLSPQSWQDIEKPMINHEIAAFSPMMQRIEEATLNALIQDSREELKAETKAPVQPSAAPEKSEITIDDFAQLDLRIAKVLACEAVEGSDKLLKFQLDVGDLGKRQVFSGIKRFHQPEELVGQLVVYVANLKPRKMRFGVSEGMILSASDDCDLQILLANGRARAGMTIS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_BURM1
Sequence: MTALKHTPLNAAHRALNARMVDFGGWDMPVNYGSQIEEHEAVRTDAGMFDVSHMCVVDFTGSRARAFFEYAIANNVGKLKTPGKALYSCLLNPQGGVIDDLIVYYFTEDFFRVVVNAGTADKDIAWFNQLNEQGGYGLTIAPRRDFAIVAVQGPNAREKVWATVPAARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEVIVPAVHVEALWNALQQHGVRPCGLGARDTLRLEAGMNLYGQDMDDTVSPLDAGLAWTVDLSTPRAFVGREALERDGTRAAFVGLILQKENGKAGGVLRAHQKVVTPHGEGEITSGTFSPSMQESIAFARVPTAVQVGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: YCIB_COXBR
Sequence: MKFLFDYFPIICFFVAYKFWGIYIATAAAMVVSALQVAIYWIRFRRFEKFHVITLIFILLLGSFTLVFHNAIFIKWKPTIVYWIFAIVLFGSHFFGKHTLVHRMLKEKIELPAKTWSRLNLSWALFFLILGVLNLFVVYNFDTNTWVNFKLFGTLVLTLVFILGQAFYIARHAQNLKMNSR
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSRP_SULSY
Sequence: MSEKVVATNKKAFHDYAILEKYEAGIVLTGSEVKSLREGACNLKDSFVMIEDGEAWLYNCYIAPYKPAAKFGHDPTRKRKLLLHKKEILKLMGKVKEKGLTIVPLRVYFKNGKAKVEIALAKGKVKYEKREAMKEKDMKREIEKSFKGKIKL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y2606_MYCBO
Sequence: MPAGVGNASGSVLDMTSVRTVPSAVALVTFAGAALSGVIPAIARADPVGHQVTYTVTTTSDLMANIRYMSADPPSMAAFNADSSKYMITLHTPIAGGQPLVYTATLANPSQWAIVTASGGLRVNPEFHCEIVVDGQVVVSQDGGSGVQCSTRPW
What are the official names of this protein?
Uncharacterized protein Mb2606c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AZG2_ARATH
Sequence: MGREKTLCKSWSDMKKHLNDTVSKSFIGRFFKLEARKTTFTTELRAATATFLTMAYIITVNANILADSGATCSINDCSTVASSSPPGPECVLGSNPGYEQCISRVKKDLVVATSLSAMVGSLAMGLLANLPFGLAPGMGANAYIAYNVVGFRGSGSISYHTAMAIVLLEGCAFLAVSALGLRGKLARLIPQTVRLACAVGIGMFIAFVGLQMNQGIGLVGPDKSTLVTLTACAETDPVTGACLGGKMKSPTFWLAVVGFLITSFGLMKNVKGSMIYGIVFVTAISWIRGTQVTIFPHTPLGDSNYNYFTKIVDFHKIQSTLGAISFTEFRKSEVWVAFATLFYVDLLGTTGVLYTMAEIGGFVEDGKFEGEYAAYLVDAGSSVVGSALGVTTTATFVESSAGLKEGGKTGLTAVIVGLYFLASMFFTPLVTNVPRWAVGPSLVMVGVMMMGVVKDIRWGETKEAVTAFVTILLMPLTYSIANGIIAGIGIYLALSMYDVVLGVAKWLNGVRKRVMREHNQVSSVATVEIV
What is the function of this protein?
Transports natural purines (adenine and guanine) as well as purine analogs.  Confers sensitivity to 8-azaadenine and 8-azaguanine (8-azg).
What are the official names of this protein?
Adenine/guanine permease AZG2, AzgA-homolog protein, Protein AZAGUANINE RESISTANT 2, AtAzg2.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSAE_RICTY
Sequence: MHTLNSEKETKNFAKLFAQNLKPNDIVLLNGDLGAGKTFFCREIIKHFCGKNTNIISPTFNLLQIYKTPNFNIYHYDMYRIKSPEEIYELGFEEALNGNLILIEWSEIIKHLLTPPLIEVNLKILDNNKRLCSIKKENFLFDFL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3B_BCHK5
Sequence: MDYVSLLNQVWQKQVNSSQEGTLAPVRPTYAYRPVQGNLQCPIKWRCIYTFAGYTGTATEPTKVLAKQEAARKVCLRLQEYGRLDGFGLRLRYSTAFEHNRYDASKSYFYTQTSSSSHE
What is the function of this protein?
Induces host cell G0/G1 arrest and apoptosis.
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host mitochondrion.
Protein: SYE_RALPJ
Sequence: MTQRVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGDFILRIEDTDVERSSQEAVDVILEAMDWLDMDIDEGPFYQMQRMDRYRAVVAQMVQQELAYPCYMSTEELDALREAQRERGEKPRYDGTWRPAPGKILPPPPAGVQPVIRFKNPIGGSVVWDDAVKGRIEISNDELDDLVIARPDGTPTYNFCVVVDDMDMQITHVIRGDDHVNNTPRQINILRALGGTPPVYAHLPTVLNEQGEKMSKRHGAMAVTGYRDAGYLPEAIVNYLARLGWAHGDAEIFSREQFIEWFDLEHLGKSPAQYNPEKLAWLNNHYIKQADNVRLAGLVKPFIEALGGKVDGGPVLADVVALVKDRANTLREVAQTALLFYRSDLAVEPELAAQHLTDDVRPGIAALAEKLGALPEWKREAIGAVFKEVLAAHGWKMPKLAMPVRLLVAGQLQTPSIDAVLELFGRDVVLHRLAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_ECO45
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TPM_PORPE
Sequence: MDAIKKKMQAMKLEKDDAMDRADTLEQQNKEANIRAEKAEEEVHNLQKRMQQLENDLDQVQESLLKANTQLEEKDKALSNAEGEVAALNRRIQLLEEDLERSEERLNTATTKLAEASQAADESERMRKVLENRSLSDEERMDALENQLKEARFLAEEADRKYDEVARKLAMVEADLERAEERAETGESKIVELEEELRVVGNNLKSLEVSEEKANQREEAYKEQIKTLTNKLKAAEARAEFAERSVQKLQKEVDRLEDELVNEKEKYKSTTDELDQAFSELSGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin Por p 1.0101, Major allergen Por p 1.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: PPIB_MYCTO
Sequence: MGHLTPVAAPRLACAFVPTNAQRRATAKRKLERQLERRAKQAKRRRILTIVGGSLAAVAVIVAVVVTVVVNKDDHQSTTSATPTDSASTSPPQAATAPPLPPFKPSANLGANCQYPPSPDKAVKPVKLPRTGKVPTDPAQVSVSMVTNQGNIGLMLANNESPCTVNSFVSLAQQGFFKGTTCHRLTTSPMLAVLQCGDPKGDGTGGPGYQFANEYPTDQYSANDPKLNEPVIYPRGTLAMANAGPNTNSSQFFMVYRDSKLPPQYTVFGTIQADGLTTLDKIAKAGVAGGGEDGKPATEVTITSVLLD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Probable peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: PSAA_EUGGR
Sequence: MTITPPEQQVKRVRVAFVSNPVETSFEKWSRPGHFSRLLSKGPNTTTWIWNLHADAHDFDNHTTDLEDISRKVFSAHFGQLAIIEIWLSGMFFHGARFSNYEAWLLDPIHVKPSAQIVWPIVGQEILNGDVGGNFQGIQITSGLFQLWRSCGITSEFQLYITALTGLIFSAVLFFAGWFHYHKAAPKLEWFQNVESMLNHHLSGLLGLGCLSWAGHQIHVSLPINKLLDSGVNPAELPLPHDFILDKSLISQLYPSFSKGLAPFFTFHWSEYSDFLTFRGGLNNVTGGLWLTDVAHHHLALAVLFILAGHMYKTNWKIGHDIKGLLESHTGPFTGQGHKGLYEIFTNSWHAQLSLNLAMMGSLSIIVAQHMYSMPPYPYIAIDYGTELSLFTHHYWIGGFCIVGAAAHAAIFMVRDYDPALNFNNLLDRVLLHRDAIISHLNWVCIFLGLHSFGLYIHNDTLSALGRPQDMFSDSAIQLQPVFAQWIQNTHYLAPTLTAFNLVSPTTPVWGGDVVSISGKVAMMPIKLGTADFLVHHIHAFTIHVTVLILLKGVLFSRSSRLIPDKASLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVAIFHFSWKMQSDVWGTVLANKVSHITGGNFSQGSLTINGWLRDFLWAQSSQVIQSYGSPLSAYGLMFLGAHFVWAFTLMFLFSGRGYWQELIESIVWAHNKLKVAPNIQPRALSITQGRAVGVAHYLLGGIATTWSFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PURQ_SYNJB
Sequence: MAGVRFGVVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSELDVVVLPGGFSYGDYLRCGAIARFAPVMGSLKEHAARGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPQGSTLTLPIAHGEGRYTCDPDTLKQLQDRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSILRSFAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_RAT
Sequence: MAAPAPGLISVFSSPQELGASLAQLVAQRAASCLEGNRGRFALGLSGGSLVSMLARDLPAATAPAGPASFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLPIPDSQVLTIDPALPVEDAAEDYARKLRQAFQGDTVPVFDLLILGVGPDGHTCSLFPGHPLLQEREKIVAPIGDSPKPPPQRVTLTLPVLNAAQSVIFVATGEGKAAVLKRILEDQESALPAAMVQPRTGALCWFLDEAAARLLSVPFEKHSTL
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_BRUME
Sequence: MKIDYYEALGVTRTADDKTLKAAFRKLAMQYHPDRNPDDPEAERKFKEIGEAYETLKDPQKRAAYDRFGHAAFENGGMGGGFGNGFGGAGGFADIFEDIFGEMMGGGRRRSNGGRERGADLRYNMEVTLEEAYAGKTAQIRVPTSITCDECSGSGAKPGSQPTTCTMCSGSGRVRAAQGFFSVERTCPGCNGRGQIIKDPCEKCHGQGRVTQERSLSVNIPAGIEDGTRIRLAGEGEAGLRGGPAGDLYIFLSVKPHEFFQRDGADLYCKVPISMTTAALGGQFEVSTLDGTQTRVKVPEGTQNGKQFRLKGKGMPVLRQSVTGDLYIQIDIETPQNLSKRQRELLEEFEKLSSQENSPKSAGFFSRMKEFFEGIGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL40_BOVIN
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK
What is the function of this protein?
Component of the 60S subunit of the ribosome.  Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
What are the official names of this protein?
Ubiquitin-60S ribosomal protein L40, Ubiquitin A-52 residue ribosomal protein fusion product 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [60S ribosomal protein L40]: Cytoplasm.
Protein: TRPC_LISMF
Sequence: MTFLEEILAQKAVEVADMPLEKVAEKRKTYSFYEFLKANTSTMQLIAEVKRASPSKGEINMGVNPVLQAKSYQAAGAGMISVLTDPVFFKGSIEDLREVAKNVEIPVLCKDFIISEKQLIRARNAGATVVLLIISALTEEMLIALFEQALALDLEVLVEVHDQKELAVAQKIGAKLIGVNNRNLHTFEVDIAVSERLASDFSSDACFISESGFRTAEDVARVSQKYNAVLVGEALMREATPEAAAKSLKVTR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: HLYBC_ECOLX
Sequence: MDSCHKIDYGLYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKVKQVKKTIDRLNFISLPALVWREDGCHFILTKVSKEANRYLIFDLEQRNPRVLEQSEFEALYQGHIILIASRSSVTGKLAKFDFTWFIPAIIKYRKIFIETLVVSVFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVVVFEIILSGLRTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARVRELDQIRNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFISPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLAGYVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLIAFNMLAGQIVAPVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLALPEINGDITFRNIRFRYKPDSPVILDNINLSIKQGEVIGIVGRSGSGKSTLTKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIIDNISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQRQRIAIARALVNNPKILIFDEATSALDYESEHVIMRNMHKICKGRTVIIIAHRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYLYQLQSD
What is the function of this protein?
Part of the ABC transporter complex HlyBD involved in hemolysin export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Alpha-hemolysin translocation ATP-binding protein HlyB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU214_DROME
Sequence: MAQNAPDCEDTQDFQFKLHHKIVAFKKCGEPRSNVNLLAVSSSRGLLFAGSPTQPELKVIIVKDLVNAKSTAQQPQARLVPLPSIPNYIACSSDGNLLAVNHTQNGTSLLSIYAVLSFMTPDVRPVYNIRLAAEDHVHGVQLLWNPVLPNSLAVVLSNGALAMYALKEGGNFEMHSLDKNQQVKCGCWSPKGKQIVLGFPGGTVKQFKPDLTLAKTLLCPPNIHDAPFDTIAIQWLSTFQFAVIFLQHGEDCSPSLYILNAPKAGAPSYINYYDICYSMNGPRNHQFVFSHVPQWNLLLVVSANGVEVGIMRSTEAGDTPAWQQLTLLDEARIEMPLSEDKDETFPLGFAFDTSTTHQLTINEKKLQTMPMVHVLSSDGELLSFNFLNVLPTAVSVCSPPPPVADTSGQFKPLNMLLASEEEEQPAWAASPSKAPAATPAASSDISFAFTPNTVTSTPAPSKDKQPSLFSGFGAAAAKAPAPQLSFGTAPTSSPVSFGAPTTNAAKPTTPFGGFGTQATTTAMGSMFSASGANAFGGMALNKPAIASVTPRTAAPGSTVPATPASAPANKPLYTVPLTFTPVDTKPATSAPPQIADESLKPDDTEPIIKDMIALQIEAFSKDIQKQKEQTKELLKGIAAPSALRAYAKRLDDLQELNEQAKDVEFELDVQGLRQGLNEAYAIVAECRGKLEIYRKPEITRLMNSSSCDPSGRRMLARLQSYVAANEAQLRLAQQHVDLQWEQFQDVVRRNSKSRMHMPCLEGIYQRLTRLQNLTSNQRIVQNNIKSKLKERGLLQAALLDQEKSRTRTNEAVDTLTDSILTMSLSQVVDSNAAKLTRERLQKIRNIVQLQKINVICPQRPDRVGLKSEVILETKRRAEQIKRAAAKPATANKYTQAAVAPPSPPDVAPTPAVAPMPQATVTVAPPLPKPMPSIPSVVEKPGVPTHPTTPVATPFSFSQSIPFVKTSTVTPTTNTVTPGEAAKPGLSIFGGSTISSFSFGGGAAKSALSFGTGSPAVAAPTPKPNPLSAVEKPTPEPTKPKEQKAAESKEFKAVQPETEESKVPQKPKAETENKSFGFGGFTGTGGTVGNTSSSPFSFGGLGSSLGFGGTAAAVPKSEPSSTATTSVATSASTAPFGIFSAALAKPSNSEPITTVTSNTTTITSKPTNVIASSSVTDAPSVTTTNAVTSSTDPIGGLFSSVTICKPNTPADTTKPANIFGGGLSAGSFSFGGTIDASKGLFGSTKPVATAPTSVTEANNKTDPISTTPSAISTTTATTTVSSPAVVPAAVTAAVPATSSTTVTSSTAVPGSAFSFSNAFSTLSAGGAAAPTTSASAPLAAKSPTATSTGNNSSNSVFGGGFAVATSTAAPVASPFQSAAKSPVSSANIFGSIPKAETSVFGGATTAPSNTTAAATPDAPPAGLFASAAISNPSPFGSPTTRAPASGGNIFGQAVKPSVFGQPAQAGDSGGSIFGGGSASTPFGSSSIFGGGNTQGAVGAPAAGSTSIFGQKVFGQSSAAAPAAGGNIFSNPVGSPQASPFGGGGNSIFGSPATAPPASGGSIFGGGSSSGGFGSFTQTTPAQGGFGGGFGQGGGGSVAQTGFGSPQAPQQQTTTPGGFGAKPVFGGSPAFGASPTFGGGATFGSPKGFGGFGGASPVASPPPFGAAAKPAQGNIFETLGGQESGLSFGNLAQTGNSNAQKPAFGGSSFMNYR
What is the function of this protein?
Part of the nuclear pore complex (PubMed:14638854).  Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad (PubMed:17682050, PubMed:20547758, PubMed:17032737).  Protects mbo/Nup88 from proteasomal degradation at the nuclear pore (PubMed:17032737).  Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export (PubMed:17032737).  Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response (PubMed:17032737).
What are the official names of this protein?
Nuclear pore complex protein Nup214, 214 kDa nucleoporin, DNup214, Nucleoporin Nup214.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localization to the nucleus membrane depends on mbo/Nup88.
Protein: PSD_YERPP
Sequence: MLDSIKIKLQYLLPKQGLTQLAGWGANKQGGWLTQLVIKAFARYYKVDMKEAQDPEFSAYRTFNEFFVRPLRAGVRPVVAEENLLAQPADGAISQLGAIREGQILQAKGHNYSLEALLAGNYLLAAEFQNGQFVTTYLAPRDYHRVHMPCDGVLREMIYVPGDLFSVNPLTAANVPNLFARNERVICIFDTAFGPMAQILVGATIVGSIETVWAGTITPPREGVIRRWTYPQAGCEGAITLEKGQEMGRFKLGSTVINLFAEGKVYFAPQLNSGAVTRMGEVLAEAVPTTPSY
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KDPC_BURCH
Sequence: MKSLIRPLVVLFVVLNAVTGLAYPAVMTVFGQAVFPSQANGSLIEQNGKVVGSALIGQPFDAPKYFWGRLSATAPMPYNAAGSGGSNLGPLNPSLADQVKARIAALRDAGTDLSKPVPVDLVTASASGLDPEITPAAAAYQVERVAKARNLTPDAVAQLVAANTTGRQFGVLGEPRVNVLKLNLALDAAQAAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CATC_RAT
Sequence: MGPWTHSLRAALLLVLLGVCTVSSDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKYEVKGSRAISYCHETMTGWVHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTYEEYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPIPKL
What is the function of this protein?
Thiol protease (PubMed:1740150).  Has dipeptidylpeptidase activity (PubMed:1740150).  Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids.  Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate (PubMed:1740150).  Can act as both an exopeptidase and endopeptidase (By similarity).  Activates serine proteases such as elastase, cathepsin G and granzymes A and B (By similarity).
What are the official names of this protein?
Dipeptidyl peptidase 1, Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, DPP-I, DPPI, Dipeptidyl transferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RL24_STAAS
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.