PharMolix/UniProtQA huggingface dataset:
Protein: PML1_YEAST
Sequence: MFHRRKRPYNTRNYGHDDKKFKSQYIDIMPDFSPSGLLELESNNKEGIALKHVEPQDAISPDNYMDMLGLEARDRTMYELVIYRKNDKDKGPWKRYDLNGRSCYLVGRELGHSLDTDLDDRTEIVVADIGIPEETSSKQHCVIQFRNVRGILKCYVMDLDSSNGTCLNNVVIPGARYIELRSGDVLTLSEFEEDNDYELIFMNV
What is the function of this protein?
Required for efficient splicing and pre-mRNA nuclear retention.
What are the official names of this protein?
Pre-mRNA leakage protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SODC_CORMI
Sequence: MVKAVCVLRGDAKVAGTVTFEQESESAPTTITWDITGNDPNAERGFHIHTFGDNTNGCTSAGPHFNPHGKTHGAPTDAARHVGDLGNIKTDGQGNAKGSVQDSHVKLIGPHSVVGRTVVVHGGTDDLGKGGNEESLKTGNAGPRPACGVIGVAN
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1156_BRUSU
Sequence: MQEALALFFGSESLLVGTIIPFLFVLTVVVFVHEMGHYLVARWCGIGAQAFSIGFGPELLGFTDRHGTRWKLSAIPLGGYVKFIGDESETSSPVGVNESALSEEDRKRAFHTQPVWKRAATVFAGPAFNIILTIAIFSVFFALYGRQIADPLIAGVQPGSPAAEAGFEPGDRFVSVEGEKITTFADVQRIVSGRAGDKLNFTVERDGKMVDLQAVPKIVERTDPLGNKVKLGAIGVETTEAVGNFRRIEYGPLESVGQAVIETGHIIGRTGEFFKRFAVGREDKCQLGGPVKIATMASKAASQGFDWLIQLMAMLSIGIGLLNLFPLPPLDGGHLVFYAVEAIKGSPVSGAAQEIFYRIGFLLVMGFMGFVLFNDLFAC
What are the official names of this protein?
Putative zinc metalloprotease BR1156/BS1330_I1152.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCIB_SHEWM
Sequence: MKQLLDFLPLVIFFAVYKMYDIYIASGALIAATALQLIVTYALYKKIEKMHLITFVMVTFFGTLTLIFHDDAFIKWKVTVVYALFAIALAVSQLLNKPILKSMLGKELVVADKIWAHVTWYWVSFFVACGLVNIYVAFSLSQETWVNFKVFGLTALTLINTVITVVYLFKNMPEEHKKELNK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AGN3_APLFA
Sequence: EEVFDDTDVGDELTNALESVLTDLKDKRDAEEPSAFMTRLRRQVAQMHIWRAVNHDRHHSTGSGRHSRFLTRNRYRYGGGHLSDA
What is the function of this protein?
HRBP is a myoactive peptide that excites Aplysia heart and enhances gut motility in vitro.
What are the official names of this protein?
Abdominal ganglion neuropeptide R3-14.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK2_PYRFU
Sequence: MIKVIERDGKVRLPFSRGILTRSITSVGVDVDLAYAIATEVQEELIRQGKKVVTKEEIRNITYQKLVEKGFKEEAKRYLFWRRFRKLKIPLIILLGGPTGVGKSTIATELAFRLGIRSVIGTDTIREVMRKIITPELLPTIHTSTFLAWKELRGTVTGSPIIAGFESQVNAVAVGVNAVIQRAIKEGLNAIIEGIHLVPGFIKIDYEMAFMYMIVARSREELEARFYERTRYSKRSAQYYISHLDEIMEIQEYLIKKAREYRVPIIENVELEKTISTIMEDIMEKTVEIMKKKGLDMLEEPK
What is the function of this protein?
Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate.  Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.
What are the official names of this protein?
2-phosphoglycerate kinase, 2PGK.
What is the protein family that this protein belongs to?
Belongs to the 2-phosphoglycerate kinase family.
Protein: TPDB2_COMSP
Sequence: MINEIQIAAFNAAYAKTIDSDAMEQWPTFFTKDCHYCVTNVDNHDEGLAAGIVWADSQDMLTDRISALREANIYERHRYRHILGLPSIQSGDATQASASTPFMVLRIMHTGETEVFASGEYLDKFTTIDGKLRLQERIAVCDSTVTDTLMALPL
What is the function of this protein?
Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD).  It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.
What are the official names of this protein?
Terephthalate 1,2-dioxygenase, terminal oxygenase component subunit beta 2, TPADO terminal oxygenase component, TER dioxygenase system, TERDOS, Terephthalate 1,2-dioxygenase small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: GCSPA_AQUAE
Sequence: MSYIPHSEEETKEILSKLGLESLEDLFSHIPKELFAKDFSFPEPKSEEELRRIFERACEDTELPLYFIGAGAYDRIIPSVIWQILSRGEFLTPYTPYQAEASQGTLQAIFEYQSLICELTGMDVANASMYDGASALAEAVLMARAIKGKGDTVVLSKALNPLYRRTVKTYLRGYEDKIVEVPYTEEGTTDLNNLEEVLKESEVHALAVQYPNFFGFVEPLKEIGELCKKYEVPFVVFVDPIALSILKPPAEFGADIVVGEGQQMGIPLSFGGPYVGFFATKKEHVRKMPGRLVGMGEDIEGKRAFTLVLQTREQHIRRERATSNICTNQNLMALANLLYMVLLGKEGMKKVAVQSLSKALYFKKELMKKGFEEVFTGKHLWEFPLRHESLKAIYRKLLKEKIVLGLPLDRFYEDLKNTTLIAVTEKRTKEEIDSVLALL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RL11_RHORT
Sequence: MAKKIIGYIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAATQGLEPGMPIPVVITAYGDRTFTYITKTPPMTYFLKKAAGIGKGSTTPGKGSAGTVTMEQVRDIAEKKMPDLNSPTIEAAVQMVVGSARSMGLQVVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y713_CHLPN
Sequence: MLEKLIKNFATYMGITSTLELDADGAYVLPISEVVKVRAQQNADNEIVLSASLGALPPSADTAKLYLQMMIGNLFGRETGGSALGLDSEGNVVMVRRFSGDTTYDDFVRHVESFMNFSETWLSDLGLGKQ
What are the official names of this protein?
Protein CPn_0713/CP_0033/CPj0713/CpB0740.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0713/CT_663/TC_0034 family.
Protein: EF1B_BOVIN
Sequence: MGFGDLKSPAGLQVLNDYLADKSYIEGYVPSQADVAVFEAVSGPPPADLCHALRWYNHIKSYEKEKASLPGVKKALGKYGPANVEDTTESGATDSKDDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEECVRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFDEYVQSMDVAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: RL21_BURCM
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIKFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL31B_CUPTR
Sequence: MKEGIHPNYREVVFQDMSSDFSFITRSTIQTKDTIVKDGKEYPLAKIEVSSESHPFYTGTQKIMDTAGRVEKFRQKFGNKLGKAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: Y591_NITEC
Sequence: MKANLGNLMKQAQQMQENMKAMQEKLATIEVEGQAGAGMVKVIMTCRHDVKRINIDSSLIGDDKEMLEDLVAAAMNDAVRRVEAATQEHMASVTSGLGLPAGMKFPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Neut_0591.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL5_ANADE
Sequence: MAARLKERYDKQLRAELMKELGFANPMQAPRLEKIVVNMGLGEAINNGKIIDASVEQLAAITGQKPVVTRARKSIANFKLRQGQSIGAMVTLRGDRMYEFFDRLVSIALPRVRDFKGVSPKAFDGKGNYTLGVREQIIFPEINYDKVEKIKGLNITVVTTARNDEEGRALLRHLGMPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LSPA_BACC7
Sequence: MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVAFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKTKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FL3H3_ORYSJ
Sequence: MSDTSKGIPQEQLPSQELHPPPMPVINLGHLSLDDPTVRSRVVNDIAKACRDLGYFQVISHGISQSVMDGAIEAASEFFKLPNEIKKEYASDDIRQPVRYDTSSKDGISMSRAFLKHYAHPLCDWLQYWPQQPPIYREYMAKYAVEVRVVALKLMEAILEGLGIGKEYMQEKFEEGLQLLSVNCYPKVSQSDTSIGLAAHSDYGLLTILLTSCQGLEVVDRSSNSWKVVQQLPHALHVHVGDHMEVLSNGRIKTVVHRAVLNPQEARISLASIHGFALHEKVSSAKELVDEENPQKYKENSFNDFLEHLTANMDNRQRNFLESLRM
What is the function of this protein?
Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants (PubMed:18413994, PubMed:18726614).  Converts (2S)-eriodictyol to (+)-taxifolin and (2S)-naringenin to (+)-(2R/3R)-dihydrokaempferol in vitro (PubMed:18413994).
What are the official names of this protein?
Flavanone 3-dioxygenase 3, Flavanone 3-beta-hydroxylase 3, Flavanone 3-hydroxylase 3, OsF3H-3, Flavonoid 3-hydroxylase, OsF3H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RGAPX_ARATH
Sequence: MPSLISQQWQERTSGFFSSSGTKLREAGQTAGSFVGEVAKDAKVNVADVAERVGSLFKSRWAILQQPATRHAVQEHLITAAATTGTFVRKGITETKEKVSVGKIKVEEAAKKTAQKSKTILTDIERWQKGVASSDVFGVAIEITVQRQESSRPIPLILVKCADYLILTGLNSPNLFKAEGDRKLIQQLVSAYNQDPRASIPEGVNPVDVAALLKYYLASLPTPLTTFELYNEIKDARSSIHRMRQSLQKLSNVNYNTLEFITALLLRVSQKSLLNKMDSHSLAMEMAPVIMWREDNRPESYREYWRRPSRSPKKSNDFETATPWDLLSDEGEGPDASSSIPLDDIARVDFGAVEVVQCLIEHHNAIFTDAAETVWR
What are the official names of this protein?
Uncharacterized Rho GTPase-activating protein At5g61530.
Protein: XERC_BACSU
Sequence: MENVKNFVKLFVEYLQIEKNYSQYTIVNYVDSIEEFETFLRVQGINGFEEAAYQDTRIFLTEAYEKGLSRRTISKKISALRSFYKFLMREKLIEENPFQLVHLPKQEKRIPKFLYQKELEELFEVSDISQPAGMRDQALLELLYATGMRVSECCSITINDVDLFMDTVLVHGKGKKQRYIPFGSYAREALKVYMNSGRQCLLMKAKEPHDLLFVNQRGGPLTARGIRHILSGLVQKASSTLHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQIYTHVSKEMLRNTYMSHHPRAFKKN
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAS_SHIFL
Sequence: MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPDLVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WEFC_STRGN
Sequence: MVEKIDFVVAWVDGNDLVWREKKAQYDGSINTFKEGMNSEKSYREWGTFKYWFRGVEKFAPWVNKIYLVTDQQKPSWLDINSEKLVLVDHTEIICNDYLPVFSANPIESNIHRIPGLSEHFVFFNDDMYLTAPVEPIDFFSEDGLPKYVTALAPITTERYGTGHFQMNDMGIITSHFSKKEILNNGHFFSFKHGIKQLIKTLLYGTTKFICGFWESHLPYPLLKSTMDLVWEKEKAVLETTSASRFRSPSDTNVWLFKYWQIASGQYAIGNPKLGGLFSLDNAGPDFWKLLNSGKYQIMCINDGHNVQDEEQVMTDFVKAMDQLLPDKSSFEI
What is the function of this protein?
Part of the type 2Gn receptor polysaccharide (RPS) biosynthesis locus.  Essential for cell surface RPS production, and for synthesis of the host-like GalNAc beta 1-3Gal (Gn) motif of the RPS.  Probably encodes a 1-3Gal alpha transferase.
What are the official names of this protein?
Receptor polysaccharide phosphotransferase WefC, Stealth protein WefC.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: CYB_MICBE
Sequence: MTNIRKTHPLMKIMNSSFIDLPAPSNISSWWNFGSLLGACLAIQIITGLFLAMHYTADTATAFSSVTHICRDVNQGWIIRYLHANGASMFFLCLFLHVGRGMYYGSFSLSETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIISALVLVHLLFLHETGSNNPLGTSSESDKIPFHPYYTIKDLLGLMFLLLTLTILVLFSPDLLGDPDNYMPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIMSILILAIIPILQTAKQRSMMFRPLSQIMFWILTADLFTLTWIGGQPVEHPFVTIGQVASILYFSLILIIMPTVSLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PTAB_PESFW
Sequence: MVGKGGYRQINKALNICAFEDYLDGQQKSLPPLNDVEQISPNVLRVLGQNPGKFTLQGTNTYIIGTGEKRLLIDTGQGIPEWADLISSTLANSSIRLSAVLLSHWHGDHTGGVPDLLRLYPHLSDSIYKHSPSKGQQPIEDGQVFEVEGATVRAVHAPGHSHDHMCFVIEEENAMFTGDNVLGHGTAAVELLSTWMATLRLMQSHNCGRGYPAHGEVIPNLNAKISGELASKERRERQVLQHLNRIRKEEQGGKGSATVQRLVVEMYGDTDQQMREQALEPFIDEVLRKLAEDEKVAFQLRAGEKTWFAIALE
What is the function of this protein?
Lactamase-like protein; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulochrin and chloroisosulochrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Lactamase-like protein ptaB, Pestheic acid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: DAZL_HUMAN
Sequence: MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDKRVHHFRRSRAMLKSV
What is the function of this protein?
RNA-binding protein, which is essential for gametogenesis in both males and females.  Plays a central role during spermatogenesis.  Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity).
What are the official names of this protein?
Deleted in azoospermia-like, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.
Protein: BAGA_PHOPM
Sequence: MKRKLFTICLASLQFACAAENLNNKSYEWDIYPVPANAGDGMVWKLHPQSDDFNYIADEKDKGKEFYAKWTDFYHNHWTGPAPTIWQRDHVSVSDGFLKIRASRPEDVPLKKVVSGPNTKELPGTYTGCITSKTRVKYPVYVEAYAKLSNSTMASDVWMLSPDDTQEIDIIEAYGGDRDGGGYGADRLHLSHHIFIRQPFKDYQPKDSGSWYKDDKGTLWRDDFHRVGVFWKDPFTLEYYVDGELVRTISGKDIIDPNNYTGGTGLVKDMDIIINMEDQSWRAVKGLSPTDEELKNVEDHTFLVDWIRVYTLVPEE
What is the function of this protein?
Cleaves the beta-1,4-linkages between beta-D-galactose and alpha-L-3,6-anhydro-galactose residues in agarose.  Cleaves agarose in a random manner with retention of the anomeric-bond configuration, producing beta-anomers that give rise progressively to alpha-anomers when mutarotation takes place.
What are the official names of this protein?
Beta-agarase, Glycosyl hydrolase 16 family protein A, GH16A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: T23O_BRASB
Sequence: MSNAPYDPATEGARMNFKGRMSYGDYLMLDRLLDAQAPLSSAHDELLFIIQHQTSELWMKLAIHEIKAAMAAIAKDDVQPAFKMLARVSRIFEQLNGAWDVLRTMTPSEYTLFRDKLGESSGFQSFQYRSIEFLLGNRNLAMLRPHAHHPELTAELEAILAKPSLYDEALKLLARRGFFIGADGQRTDWRGTRSESPEVAAAWTSVYRDPQRHWELYELAEKLVDFEDYFRRWRFNHVTTVERIIGFKTGTGGTSGVNYLRKMLEIVLFPELWKLRTGL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: HSLU_METEP
Sequence: MTTFSPREIVSELDRFIVGQKDAKRAVAIALRNRWRRQQLKGPLRDEVAPKNILMIGPTGCGKTEIARRLARLAGAPFLKIEATKFTEVGYVGRDVEQIVRDLVEVGIGLTREEKRKAVKAKAEAAAESRILDALVGPTASQATRESFRKKLRASELDDKEVEIELAPSGSQGLPMFEIPGMPGASMGAINISDMLGKALGGQRGKPRRITVAEAYAPLIAEESDKLVDDDALTREAIREVEDNGIVFLDEIDKICAREGRSGADVSREGVQRDLLPLIEGTTVATKHGPVKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELQPLTVEDFKQILTATEASLIKQTVALMETEGVTLDFTEDAIDALARVAVEVNGSVENIGARRLQTVLERVIDEISFTATDRSGETVPIDAAYVRDRVEDLAANADLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_SHESR
Sequence: MPLTVNCPICKTPVEWVPQSEFKPFCSERCKMIDLGDWASEKHAIPVKSEFDLDALDELGYDEESFFKE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: CE15_UNKP
Sequence: MQRTCVLIVLIVTSTMWTPDPDVYAQPRGFNYDEAQVPKYTLPDPLVMVDGTKVTSAKQWNDKRRDEVQQLFEAYMYGKVPDGETELIFTDAKGERALGGAAIRKQVKISFGEKEDAPAMDLLIYLPADAKVRVPVFLGLNFHGNHTIHKDKEIWLTESWVRTNKKFGITKNKANELSRGVAAGRWQIEKAIAKGYGVATIYCGDIDPDFNFPSNGIQAYYYKKDQTIPEKGQWGTIAAWAFGLSCAMDYFETDTDIDHKKVAVLGHSRLGKTSLWAGAIDTRFALTISNCSGCGGAALSRRRFGETVRRINTSFPHWFCSRFHQYNDKEDKLPIDQHMLIALCAPRPVLINSATEDKWADPHGEFLAAQGADAVYRMLGTGGLDAKKWPEPNKLVKSTIGYHLRPGKHDVTARDWDVYIEFADHHMTGGAE
What is the function of this protein?
Displays some glucuronoyl esterase activity in vitro, since it is able to hydrolyze methyl 4-O-methyl-D-glucopyranosyluronate, allyl D-glucuronate, benzyl D-glucuronate and D-glucuronic acid methyl ester.  However, esters of glucuronic acid are probably not its biological substrate, as they are not present in the marine environment.  Can also hydrolyze a range of other esters, including p-nitrophenyl acetate.  More likely biologically-relevant substrates for MZ0003 and other marine bacterial CE15s are algal cell wall polysaccharides, as these would be readily available in this environment and could be used as energy sources.
What are the official names of this protein?
Carbohydrate esterase MZ0003.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 15 (CE15) family.
What are the subcellular locations of this protein?
Periplasm.