PharMolix/UniProtQA huggingface dataset:
Protein: IQGA1_HUMAN
Sequence: MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK
What is the function of this protein?
Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton.  Binds to activated CDC42 but does not stimulate its GTPase activity.  It associates with calmodulin.  Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane.  May promote neurite outgrowth (PubMed:15695813).  May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).
What are the official names of this protein?
Ras GTPase-activating-like protein IQGAP1, p195.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm. Note=Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816).
Protein: THII_SHEHH
Sequence: MKFIVKLFPEIMMKSKPVRMRFTKMLETNIRNVLKKVDESAKVQRQWDKIMVMVPDDRPDLVEAFGERLACIPGIAHVLQVNVSTFTSVDDIYQQTLVAYKEQLVGKTFCVRVKRAGKHDFNSIEVERYVGGGLNQFTEAAGVRLKNPDMTVHLEIDNDNLYLIDKRIEGLGGFPMATQEDVLSLISGGFDSGVSSYQFIKRGSRTHYCFFNLGGDQHEIGVKQVAYHLWQKYGESHKVKFISVPFDPVVQEILERIDNGQMGVILKRMMMRAATRVAQKMGIQALVTGEAMGQVSSQTLTNLNVIDRCTEQLILRPLIAMDKQDIINLSRQIGTEDFAKSIPEYCGVISQKPTVKAVLSKVEAEEAKFSEDLLDRVIADAEIIDIREIATQMDTKITETETVDSINANEIIIDVRAPEEEEKSPLKIDGVEVKAIPFYKLATQFADLDKDKSYLLYCDRGVMSKLQALYLQEQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L_MABVO
Sequence: MQHPTQYPDARLSSPIVLDQCDLLARSLGLYSHYSHNPKLRNCRIPHHIYRLRNSTALKTFLQNCSILTVPFHSIWDHILTSIQYDAINHVDDFKYLLPSELVKYANWDNEFLKTYLNKILRLDHVFPASARSQCEDFSPKENPYYWGMLLLVHLSQLARRIKGQRGSLRSNWKFIGTDLELFGIADFIIFKVPVKTIIRNAVSLQASKPGLRVWYRDQNLTPYLCDDEFIVSVASYECFIMIKDVFIERYNTWEICARAWLEDSDGADYPPLDVLGELYNYGDQIIAMYLEDGFKLIKHLEPLCVSCIQTHGIFTPRKYWFQSQMIKSYYDELCDLNLKLRISDNKAECAQNFIKTIIQARLTPQQYCELFSLQKHWGHPVLYNDVALDKVKKHAQATKILKPKVMFETFCVFKFIVAKNHYHSQGSWYKTTHDLHLTPYLRQHIVSNSFPSQAEIYQHLWEWYFVEHEPLFSTKIISDLSIFIKDRATAVNQECWDSVFDRSVLGYNPPVRFQSKRVPEQFLGQADFSLNQILDFAEKLEYLAPSYRNFSFSLKEKELNIGRTFGKLPYRVRNVQTLAEALLADGLAKAFPSNMMVVTEREQKEALLHQASWHHNSASIGENAIVRGASFVTDLEKYNLAFRYEFTRHFINYCNRCYGVKNLFDWMHFLIPLCYMHVSDFYSPPHCVTEDNRNNPPDCANAYHYHLGGIEGLQQKLWTCISCAQITLVELKTKLKLKSSVMGDNQCITTLSLFPIDAPNDYQENEAELNAARVAVELAITTGYSGIFLKPEETFVHSGFIYFGKKQYLNGVQLPQSLKTMARCGPLSDSIFDDLQGSLASIGTSFERGTSETRHIFPSRWIASFHSMLAINLLNQNHLGFPLGFNIDISCFKKPLTFSEKLIALITPQVLGGLSFLNPEKLFYRNISDPLTSGLFQLKNALEFLGKGELFYILIAKKPGLADASDFVMNPLGLNVPGSREIITFLRQTVRENITITSQNRIINSLFHIGSDLEDQKVCEWLLSSNPVMSRFAADIFSRTPSGKRLQVLGYLEGTRTLLASRTISLTTEGTMLMKLRELTRNRWKSWFSYIDALDDDLSESLEKFTCTVDVANFLRAYSWSDVLKGKRLIGATLPCLLEQFKVKWINLSEDLREQFNLSSESELTINLLPYDCKELRLGGSHDTELNYVSCALDRKVVQKHPSVKRLAWTIGNRAPYIGSRTEDKIGYPPLRVNCPSAALKEAIEMVSRLLWVTQGTADREKLLIPLLNSRVNLDYQTVLNFLPTHYSGNIVHRYNDQYGQHSFMANRMSNTSTRAIISTNTLGKYAGGGQAAIDSNIIFQNTINLGVAVLDIALSLAKLSSASNVTFRLMLNKCCTRHVPSEYLFFDKPLDVDLNKYMDNELVYDNDPLCSGIKGRLGRVSRSTLSLSLNVSDIGSYDFPTIAAWTLGETIVGSIFSDESSQSTDPISSGCTKTFVTHFLVYPVESIFYAFGANLIVESLSLSRIKSIKNLSDLTFLISSTIRNLSHRSLRILQSTFRHELVLTRLAHHIPLISLMLGGSAGEKSSSDAVRLFLTASYQNFIHNFSCLMKKGQSSLPVWLYFPSEGQQLKPILKILQRLSDLLSPDKVQRCKTLADTCCSIDSFWVYPSKSTRTNHYYASLNYWRDKANKVKNTPFSHLINCSFLELSSHTSSVSSNQQVTNSKYIVHPEDIPEINTRTKLIEYGSTALQRMDIKMPPSEQNLVENCRPSKDIRFKDNQKITKHDQRYEKKESSQQQMSPEDNMQTLAYMHNSSPSQTFIKSIDVHEDFDASRVILNSKINNFNLTDCTINTNLLTTPTGTEFLDTSPLQSSRYSSTPRERSLLSREQASYLYVDCSNIPSISLDPGFRNMSDQNQIQMLINAYKRDLHACFDSNQFCRFTGVVSSMHYKLYDLLPPGELRKAICLAEGEGSGARLLLKWKETDHLFFNTLATDSQQEAEILSGRVIPRMLYNIDRLSALLESRRLILNNLTIQITDITNPLWLDSVIQYLPEDSDILTMDAETTKDETREQLYKTIVNIWTRTSPNIPKISIIKVFLLDYEGTLFLMKNAIQYYGQVQLKKPYSSNAKNSEWYLCCSKRRIQRLQIDFPDQVGIFLICKAMSRQRQAIPYWLKHIEKNYPASLHEFFLTLGFPSLESSFCHRYTIPFSEGKALFHKVQSYVRQGKQHLHSLMLDYENNSPLLDLRNHFICSLRGKITKYYNDILKLNLVIKAVEKGKNWSQLVETLPNMHSVCIVHVDHECFGCEKRLLLKLDFIRNTKIAEQKLLNRVIGYILFFPFGLSKSRSLRA
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: SPCS2_ARATH
Sequence: MEEKKTESTNKNVKKANLLDHHSIKHILDESVSDIVTSRGYKEDVRLSNLKLILGTIIIVVALVAQFYNKKFPENRDFLIGCIALYVVLNAVLQLILYTKEKNAILFTYPPEGSFTSTGLVVSSKLPRFSDQYTLTIDSADPKSISAGKSVQLTKSVTQWFTKDGVLVEGLFWKDVEALIKNYAEEEPKKKK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PNP_LACP7
Sequence: MYKSFSMELAGRTLSVDVGRVAAQANGAAFMHYGDTVVLSTATASDKPREGIDFFPLSVEYEEKLYAVGKVPGGFNKREGKASENAILTSRVIDRPMRPLFPKDYRNDVTLNNLVMSVDPDCSPELTAMLGSAISVAISDIPFDGPCATTQVGLVDGELVFNPTAAQKAVSDLALTVASTRDKVIMIEAGANEVPEDKMLEAIFAAHEVNQEVIQFIDKIVAEFGKEKHGYISCEIPEEMFAAIKEVVTPEQMEEAVFTDVKQVREENIREIKNKLAEVFEESNPEWLHLIDEAVYKYQKKTVRKMILKDHKRPDGREIHQIRRLAAEVDMLPRVHGSGMFTRGQTQILTVTTLAPLSEAQKLDGLDEAEKSKRYMHHYNFPSYSVGETKPSRGPGRREIGHGALAERALIPVLPSEAEFPYAIRTVSETMESNGSTSQASVCASTLSLMAAGVPIKKQVAGISCGLVTGDTDDDYLVLTDIQGLEDFFGDMDFKVAGTHDGITAIQMDIKIHGLTRAIIEEAIRRTKEAREYIINEVMTPAIAEPRTEVGKYAPKIIQIQIDPQKIGDVVGQRGKTINAIIEQTGVKIDINDEGAVSVCGTDKDMMDKAINMIRTIVTEFEEGQVFEGKVISIKEFGAFLEFAPGKEGMVHISKISKERINHVEDVLTLGDVVKVVCLGKDKMGRISFSIKDYKEEN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC4_BGYMJ
Sequence: MRLFSSKVNSSAQIKDCSTWYPQPGQHISIRTFRELNQVPTSKNTSTKMESQSNGDNSKSTADLQEEVSSLPTTHTQRH
What is the function of this protein?
Pathogenicity determinant.  May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein AC4, Protein AL4.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AC4/C4 family.
Protein: GSLG1_RAT
Sequence: MAVCGRVRRMFRLSAALQLLLLVAAGVQNSHGQGQGLGVNFGPFAGQAGGGNPVGQQPPQLPQLSQQQQQQQPPPQQQQPFPAGGLPARRGGAGPGGTGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTISEIKECAEEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIFSDYRLICGFMDDCKNDINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVSELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKVVRGEKGSLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSCLMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMPPGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIHNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKSDIKNYCSTVQYGNAQIIECLKENKKQLSTRCHQRVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIITQESALDYRLDPQLQLHCSDEIANLCAEEAAAQEQTGQVEECLKVNLLKIRTELCKKEVLNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPADGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR
What is the function of this protein?
Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).
What are the official names of this protein?
Golgi apparatus protein 1, E-selectin ligand 1, ESL-1, Golgi sialoglycoprotein MG-160.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type I membrane protein. Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Golgi medial cisternae (PubMed:2909545). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (PubMed:31522887).
Protein: PXPA_CAMJ8
Sequence: MFKVDLNSDLGESFGAYKMGMDEEILKFVSSVNVACGFHAGDPCVMDKTLNLAKQNGVCIGAHPSYPDLLGFGRRNMQISFEEAKNYALYQLGALFGFAKAKGMKIQHFKAHGALYNMAAIDENLALALCEAVASFDENIIFLGLSNSAMNEAAKKKGLRYANEVFADRAYNDDGTLVSRKLEGALIHDENLAIKRVIKMIKESKVTSINGKEIDLKADSICVHGDNIKALEFVKKIKENLEKEQIQICALENFI
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: EPIP1_EPING
Sequence: ADGIVAVELDTYRGSFXK
What is the function of this protein?
Has a serine protease activity.
What are the official names of this protein?
Major allergen Epi p 1, Allergen EpI n I4625*.
Protein: ELN_CHICK
Sequence: ARQAAAPLLPGVLLLFSILPASQQGGVPGAIPGGGVPGGGFFPGAGVGGLGAGLGAGLGAGGKPLKPGVSGLGGLGPLGLQPGAGVGGLGAGLGAFPGAAFPGAASAAALKAAAKAGAGLGGVGGIGGLGGVGGVGVPGGLGVPGVVQPGVGAAGKPPKVPGAGIPGAFPGGGVLPGAGIRFPGVGVLPGVPTGTGIKAKGPGAGAFAGIPGGYRLPFVNGLGPGGIGAGVLAGKAGYPTGTGVGAQAAAAKAAAKYGAGVLPGAGGIPGVGGVVPGVGVVPGAGVGGPAAAAAAAKAAAKAGAYGAGVLPGAGGVPGVVPGVGVVPGLVPGVGGIPGVAGVGTPAGAAAAAAKAAKYGAGVPGVGVPGVGIGGVPGVPGVPGVPGVPGVPGVPGVPGVPGVPGVPGVPGVVPGVGVGGPAAAAAAKAAAKAAAFGAGRVPGVGVPGAVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGLVPGAGPAAAAKAAAKAAKYGAGGLAPGVGGLAPAVGGLAPGVGGLVPGVGGLVPGVGGLAPGVGGLAPGVGAVPGVGGPAAAAKAAAKAAKYGAGVGGVPGAVPGAVPGVPGVPGVTPGVGGVPSLVPGVGVPGVGVLPGAGIPQVGVQPGAKPPKFGVPGAGVPGVGGIPGGLGVGGLGVGGLGAGGLGAGVGVPGFGVSPIFPGGVGGQLGFGGKPPKTYGGALGALGFRGGVGCAQGKYCGRKRK
What is the function of this protein?
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.
What are the official names of this protein?
Elastin, Tropoelastin.
What is the protein family that this protein belongs to?
Belongs to the elastin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Extracellular matrix of elastic fibers.
Protein: AROD_STAHJ
Sequence: MTNVEVAATVAPNQLLDTLTLDNIKEYSNDIDIIELRIDQWEDRHLELLKSNLEQLQELNINANVLVTYRTISQGGKGEMTHEAYMTLLKEIIKNHHCQMIDIEWDSDFDVFAHRDLINLAHRYNKQVVISYHNFQETPDIDILKFTYYKMNQLNPDYVKIAVMPQDKEDVATLLEAVATSADTLDAKVIGISMSKVGLVSRTAQGVFGGTVSYGCLGEPQAPGQIHVKTLKQQLLFYSNH
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: YUMB_BACSU
Sequence: MALNKPKIVILGAGYGGLMTVTRLTKYVGPNDADITLVNKHNYHYETTWMHEASAGTLHHDRCRYQIKDVINQSRVNFVQDTVKAIKIDEKKVVLANGELQYDYLVIGLGAVPETFGIKGLKEYAFPIANINTSRLLREHIELQFATYNTEAEKRPDRLTIVVGGAGFTGIEFLGELAARVPELCKEYDVDRSLVRIICVEAAPTVLPGFDPELVDYAVHYLEENGVEFKIGTAVQECTPEGVRVGKKDEEPEQIKSQTVVWAAGVRGHPIVEEAGFENMRGRVKVNPDLRAPGHDNVFILGDSSLFMNEDTERPYPPTAQIAMQQGITVAKNLGRLIKGGELEEFKPDIKGTVASLGEHNAVGVVYGRKLKGTPASFMKKVIDNRSLFMIGGLGLTLKKGKFKFF
What are the official names of this protein?
NADH dehydrogenase-like protein YumB.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: BIOW_STAAE
Sequence: MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: RS3_MYCA1
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYADYVKEDVAIRRLLSTGLERAGIADVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLNILEVRNPESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDVVGGKRELAAAAPAGAERPRRERPSGTRPRRSGASGTTATGTEAGRAAASADESTAAGQPAEAAPAAEPQSTES
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NRDR_SPHAL
Sequence: MRCPYCGHEDSQVKDSRPTEDGAAIRRRRQCEDCGARFTTFERIQLREVVVIKAGGTREPFDREKLMRSVQIACRKRPIDGARIERLVSGIQRQLETSGENEVQASQIGAMVMEALKGFDNVAYIRFASVYRDFTEARDFEEFASTITEAARPIK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RNP1_ARCFU
Sequence: MRGRLQGVELIARDWIGLMVEVVESPNHSEVGIKGEVVDETQNTLKIMTEKGLKVVAKRGRTFRVWYKGKIMRIKGDLINFRPEDRIKRGLMMLKRAKGVWI
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29, aRpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1563_NEIMF
Sequence: MAGHSKWANIQHKKARQDAKRGKIFTRLIKEITVAARMGGGDPGANPRLRLALEKAAENNMPKDNVQRAIDKGTGNLEGVEYIELRYEGYGIGGAALMVDCLTDNKTRTVADVRHAFTKNGGNLGTDGCVAFNFVHQGYLVFEPGVDEDALMEAALEAGAEDVVTNDDGSIEVITAPNDWAGVKSALEAAGYKSVDGDVTMRAQNETELSGDDAVKMQKLIDALEDLDDVQDVYTSAVLNLD
What are the official names of this protein?
Probable transcriptional regulatory protein NMC1563.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_PSEE4
Sequence: MGAIPLEHGLAVAGILFCLGLVGLMVRRNILFVLMSLEVMMNASALAFIVAGARWVQPDGQVMFILVISLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURQ_PROMA
Sequence: MKNYNLSDNINRSNILTEESNHLSKNIDTVSTSKLVDIFVEEDKKPQQAISQAKHQITKSIDLIYQRLIDNGRLFYIGAGTSGRIAVLDAVECPPTFCTSPELVQAVIAGGSSSLINSSEEKEDSNSLSIKDLKERNFSSKDCLIGITAGGTTPYVLSGLNYARNIGALNIAITSVPEQQASFGSNITIRLITGPEIIAGSTRLKAGTATKMALNIISSGVMIKLGKVFDNKMIDVSISNKKLFDRALRITSSLLNIEMKEAQLLLDQAKGSIKVACIIKSSGMDQKSAFALLERNNHNLRKALKDINIEF
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MOT1_RAT
Sequence: MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV
What is the function of this protein?
Bidirectional proton-coupled monocarboxylate transporter.  Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH.  The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate.  MCT1 is a major lactate exporter (PubMed:9374487, PubMed:9639576, PubMed:10417314, PubMed:19473976, PubMed:8526936, PubMed:10564700, PubMed:11719518, PubMed:17127621).  Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis (By similarity).  Facilitates the protonated monocarboxylate form of succinate export, that its transient protonation upon muscle cell acidification in exercising muscle and ischemic heart.  Functions via alternate outward- and inward-open conformation states.  Protonation and deprotonation of 302-Asp is essential for the conformational transition (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURB_COXB1
Sequence: MDKENFTRLRGELFCDHPLARYTSWRVGGKAERFYRPADLFDLQDFLTQLPSDEPLTWLGLGSNVLIRDGGIKGTVILTLNRLKELSVVNSQLAFREKSGTEDFFSGNGKTIIRAEAGVTCAKLAKFCVSQGLEDGAFFAGIPGTVGGALAMNAGAFGGETWRTVIGVETMNHQGEILKRTPDEFKIHYRQVEGLENQFFIAGYFCFNHGDPDKAKTAINALLKKRNLSQPIGKYSCGSVFRNPPGDYAARLIESAGLKGKSIGSAEVSEKHANFILNKGNASAADIEALIHYVAQHVSQIHGIQLVKEVHIIGRS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_TRICV
Sequence: MKVRPSVKKMCDKCRVIKRKGKIMVICPNAKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TBG2_HUMAN
Sequence: MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWGTQEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.  Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
What are the official names of this protein?
Tubulin gamma-2 chain, Gamma-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.