PharMolix/UniProtQA huggingface dataset:
Protein: FZD6_PONAB
Sequence: MEMFTFFLLTCIFLPLVRGHSLFTCEPITVPRCMKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTCTEQIHVVPPCRKLCEKVYSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFWCPRHLKTSGGQGYKFLGIDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSDHCRQYHIPCPYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFFKRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATANHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDRKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKGSTSLLVHPVSGVRKEQGGGCHSDT
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism.  Involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.  Together with FZD3, is involved in the neural tube closure and plays a role in the regulation of the establishment of planar cell polarity (PCP), particularly in the orientation of asymmetric bundles of stereocilia on the apical faces of a subset of auditory and vestibular sensory cells located in the inner ear (By similarity).
What are the official names of this protein?
Frizzled-6, Fz-6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell surface. Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with FZD3 at the apical face of cells (By similarity). Localizes to the endoplasmic reticulum membrane in the presence of LMBR1L (By similarity).
Protein: YPHD_ECOLI
Sequence: MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEVPLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIDENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YphDEF.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein YphD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NR1I3_CALUR
Sequence: MASGEDGPRSCMVCGDRATGYHFHALTCEGCKGFFRRTVSKNTGLTCPFAGNCKVNKAQRRHCPACRLQKCLDAGMKKEMILSAEALVQRRAKQAQRRAQWAPVQLSKGQQELVQTLLGAHARHVGTMFDQFVQFRPPAHLFIHHQRLPIPVPALPLLKHFAEVNTFMVQEVIKFTKDLPLFRSLPMEDQISLLKGAAVEICHIALNTTFCLQTRNFLCGPLCYALEDGVHVGFQEEFLELLFRFHATLRRLQLQEPEYVLMAAMALFSPDRPGVTRREEIDRLQEVTALTLQSYIKGQPPRPRDRFLYAKLLGLLAELRSIDNAYGYQIQHIQGLSAMMPLLQEICS
What is the function of this protein?
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes.  Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 1 group I member 3, Constitutive androstane receptor, CAR.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7.
Protein: CYB_MACMU
Sequence: MTPMRKSNPILKMINRSFIDLPAPPNLSMWWNFGSLLAACLILQIITGLLLAMHYSPDTSSAFSSIAHITRDVKYGWITRYLHANGASMLFICLFLHIGRGLYYGSYLLLETWNIGIMLLLMTMTTAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVQWIWGGYAIDSPTLTRFFTLHFILPFIIIALTTVHLLFLHETGSNNPCGISSDSDKIAFHPYYTTKDILGLVLLLFILATLTLLSPNLLNDPDNYIPADPLNTPPHIKPEWYFLFAYTILRSIPNKLGGVLALFLSILILAAIPMLHKSKQQSMMFRPLSQFLFWLLITILLTLTWIGSEPVVQPLTTIGQVASMMYFITILILMPLASLIENNLLKWT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FABH_BRUA1
Sequence: MIRSVVRGIGSALPKRVMKNTDFEGIVETSDEWIVQRTGIRERHIAGEGETTVSLGAAAARAAIENAGLQPSDIDLVLLATSTPNNTFPASAVAIQRELGITRGFAFDLQAVCSGFIYAITTADLYIRGGMARRVLVIGAETFSRILDWTDRTTCVLFGDGAGAIVLEAAEGHGLTSDRGILAANLRSDGNHKEKLYVDGGPSTTQTVGHLRMEGREVFKHAVGMITDVIEASFEATGLTAEDIDWFVPHQANKRIIDASAKKLHIAEEKVVITVDRHGNTSAASVPLALATAVADGRIKKGDLVLLEAMGGGFTWGAVLVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_FRATM
Sequence: MIEIKKAKPTSPGRRHVVSVKNTELHTGKPFKGLVEVKKSKAGRNNTGRITVRHQGGGHKQHYRVVDFKRNKDDITAKVERIEYDPNRSANIALVLYADGERRYIVAPKGLKKDMSVISGEKVDVAVGNCMPLRNIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGKDNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRRNKRSNKLIVQKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CYB_ELIGR
Sequence: MTNIRKTHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGICLILQIATGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGMYYGSYMSIETWNMGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIVVALAMVHLLFLHETGSNNPSGLNSDADKIPFHPYYTVKDILGVFLLILFLASLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLALLPHLHTSKQQSLMFRPLSQTLYWILVADLLVLTWIGGQPVEYPFIVIGQLASILYFTIILIFMPMAGMIEDNILKMA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KDPA_CLOAB
Sequence: MEILQIAIILIVFVLLCIPIGRYMYKVSEHKKTLLDPVLDKIDGFIYKLSGIQKEEEMNWKQYIFALLMCNAVPAIIGYIILRIQAVGIFNPNHVKGMEQGLTFNTIISFLTNTNLQDYAGETGASYLSQMIVITFFMFFAAATGIAVALAFIRALSGKKKLGNFYVDLVRITTRILLPLSIIVAIFYIGQGVPQTLSANKTVTTIEGKLQNIPLGPVASLEAIKLIGTNGGGFFSANSSHPFENPTPLTNSVQIITLLLLAGSMVVCFGHMIKKKKQAVAIFAAMMVLLLAGAAICFSAEKAGNPALSRIGLSQSMGNLEGKEERFGIAGSSLFTTVTTDTSCGAVNNMHDSLTPIGGAVPLINMMLNVIFGGVGVGFMNMIMYAILTVFLCGLMVGRTPEFLNKKIEGKEIKLVAFAIIVHPFLILMSSALALTTKQGLAGISNPGFHGLTQVLYQFTSSAANNGSGFEGLIDNTMFWNVSAGVVMFLGRYLSIIILLAVASSFAAKRAVPATQGTFKTDNTIFTVTLIVIIVIIGALTFLPAVALGPISEYLTL
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYOE2_SHEFN
Sequence: MTKPLTISQVQPKITLQWRAYFEMTKPKVVALMLLTVLVGMCLSVPGIVPLQPLVAGMAGIAMMAGSAAAFNHLIDRKIDGLMARTYNRPLPKGKISTTKAVTFAVSLGSLGFVVLYTLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAITNELHGYALLLVIIIFTWTPPHFWALAIHRRKEYAKVDIPMLPVTHGVEFTKTCILLYTILLAIACLLPVLVGMCGPIYLVGSTVLSCGFIYKAWQLKFHDYPELSMQVFKFSIYHLMVLFIVLLVDHYFWVNA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SC5AC_BOVIN
Sequence: MEVKNFAVWDYVVFAALFIISSGIGVFYAIKERKKATSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPADVYRFGASFVLFFITYGLVIILTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTYAGGLHNVLEQAENGSRLNIFDFDIDPLRRHTFWTISVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILLCAVFSGLTMYAHFKDCDPWTSGIISAPDQLMPYFVMELFSTMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPRLSDKLSTWISKGLCLLFGVICTSTAVAASLMGGVIQAALSIHGMCGGPMLGLFSLGILFPFVNWKGALAGLLTGILLSFWVAIGAFIYPAPASKTWPLPLSTDQCGLSNVTESVPPVLSSRPAIAETWYALSYLHYSTVGCLGCIAAGVIISFLTGLQKGKDIPPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENDSTWKQGAESVLQNGLKQESLVPGYDPKDKSYDNMALEKITHF
What is the function of this protein?
Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.  Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate.  May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine.  May play also a role in monocarboxylates transport in the retina.  Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity).
What are the official names of this protein?
Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity).
Protein: PURA_KOMPG
Sequence: MADVVLGSQWGDEGKGKLVDVLCEDIDVCARCQGGNNAGHTIIVKGVKFDFHMLPSGLVNPKCKNLIGSGVVIHLPSFFEELEAIENKGLDCTGRLFVSSRAHLVFGFHQRTDKLKEAELHETKKSIGTTGKGIGPTYSTKASRSGIRVHHLVSDEPDSWKEFETRLSRLIETRKKRYGHFDCDLESELAKYKVLREKIKPFVVDSIEFMHDAIKDKKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPKAINNIYGVVKAYTTRVGEGPFPTEQLNEDGEKLQTIGCEYGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIKIGVSYTYQGKRVTTFPEDLHALGKVDVEYVTFPGWEEDITQIKNYEDLPANAKKYLEFIEEYVEVPIQWVGTGPGRESMLEKNI
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_ZYGCR
Sequence: MKPISNPMGLSPTKQNVYDSVVLTTLQDVSNWVRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIVDAIIKLRKKVAQENGQDRLNQNQQHRCFSVTHRLQPVPAVHNGEYERNITRQVPSISLDSTLQSPFEQILQSSFESVSETTLIDSQRYDNQYLQGAEIETGGLE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: YP027_YEAST
Sequence: MVGIYRILASFVPLLGLLFAFHDDDMIDTVTIIKTVYETVTSTSTAPAPAATKSVSEKKLDDTKLTLQVIQTMVSCFSVGENPANMISCGLGVVILMFSLIIELINKLENDGINEPQRLYDLIKPKYVELPSNYVNEKIKTTFEPLDLYLGVNMNTSGSELNQNCLILKLGEKTALPFPGLAQQICYTKGASNEFTNYKLSDIQGNLNENSQGIANGVFQKISNIRKISGNFKSQLYQISEKITDENWDGSAVGFTAHGREKGPNKSQISVSFYRDN
What are the official names of this protein?
Uncharacterized membrane protein YPR027C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UNG_ACIB5
Sequence: MQLTEQQQDKLSKVQLEESWKRSLTPFLLSPYMDSLRDFLFQQKQAQKTIYPPSKQIFNALNITPLDHVKVVILGQDPYHGPNQANGLSFSVQRGVALPPSLRNIFHELHTDLGVPISRHGDLTKWAEQGVLLLNSVLTVEAGQPTSHQKQGWEEFTDAVIDVLNEQREHIVFILWGAYAQRKGQRINREKHLVLTAAHPSPLAANRGGFFGCKVFSKTNQYLKQHGIEPIDWQLDA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EREC1_ORYSJ
Sequence: MTPAPAAASYRALVALLLVAVAVADDGSTLLEIKKSFRNVDNVLYDWAGGDYCSWRGVLCDNVTFAVAALNLSGLNLGGEISPAVGRLKGIVSIDLKSNGLSGQIPDEIGDCSSLKTLDLSFNSLDGDIPFSVSKLKHIESLILKNNQLIGVIPSTLSQLPNLKILDLAQNKLSGEIPRLIYWNEVLQYLGLRGNNLEGSISPDICQLTGLWYFDVKNNSLTGPIPETIGNCTSFQVLDLSYNKLSGSIPFNIGFLQVATLSLQGNMFTGPIPSVIGLMQALAVLDLSYNQLSGPIPSILGNLTYTEKLYMQGNKLTGPIPPELGNMSTLHYLELNDNQLSGFIPPEFGKLTGLFDLNLANNNFEGPIPDNISSCVNLNSFNAYGNRLNGTIPPSLHKLESMTYLNLSSNFLSGSIPIELSRINNLDTLDLSCNMITGPIPSTIGSLEHLLRLNLSNNGLVGFIPAEIGNLRSIMEIDMSNNHLGGLIPQELGMLQNLMLLNLKNNNITGDVSSLMNCFSLNILNVSYNNLAGVVPTDNNFSRFSPDSFLGNPGLCGYWLGSSCRSSGHQQKPLISKAAILGIAVGGLVILLMILVAVCRPHSPPVFKDVSVSKPVSNVPPKLVILHMNLSLLVYEDIMTMTENLSEKYIIGYGASSTVYKCVSKNRKPVAVKKLYAHYPQSFKEFETELETVGSIKHRNLVSLQGYSLSPVGNLLFYDYMENGSLWDVLHEGPTKKKKLDWETRLRIALGAAQGLAYLHHDCSPRIIHRDVKSKNILLDKDYEAHLTDFGIAKSLCVSKTHTSTYVMGTIGYIDPEYARTSRLNEKSDVYSYGIVLLELLTGKKPVDNECNLHHLILSKTANNAVMETVDPDIADTCKDLGEVKKVFQLALLCTKRQPSDRPTMHEVVRVLDCLVRPDPPPKSAQQLAMPQRPAVPSYINEYVSLRGTSVLSCANSSCTSDAELFLKFGEVISQNTE
What is the function of this protein?
Receptor kinase involved in the regulation of thermotolerance (PubMed:26280413).  Functions as positive regulator of heat tolerance (PubMed:26280413).  May be involved in the regulation of cell proliferation and cell growth (PubMed:29692796).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase ER1, ERECTA homolog 1, ER homolog 1, OsER1, Receptor-like cytoplasmic kinase 204, OsRLCK204.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OMPB1_NEIGO
Sequence: MKKSLIALTLAALPVAATADVTLYGAIKAGVQTYRSVEHTDGKVSKVETGSEIADFGSKIGFKGQEDLGNGLKAVWQLEQGASVAGTNTGWGNKQSFVGLKGGFGTIRAGSLNSPLKNTDANVNAWESGKFTGNVLEISGMAKREHRYLSVRYDSPEFAGFSGSVQYAPKDNSGSNGESYHVGLNYQNSGFFAQYAGLFQRYGEGTKKIEYEHQVYSIPSLFVEKLQVHRLVGGYDNNALYVSVAAQQQDAKLYGARRANSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGTVDSADHDNTYDQVVVGAEYDFSKRTSALVSAGWLQEGKGADKIVSTASAVVLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.  Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
What are the official names of this protein?
Major outer membrane protein P.IB, PIB, Protein IB, Porin.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: 14336_ARATH
Sequence: MAATLGRDQYVYMAKLAEQAERYEEMVQFMEQLVTGATPAEELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEESRKNDEHVSLVKDYRSKVESELSSVCSGILKLLDSHLIPSAGASESKVFYLKMKGDYHRYMAEFKSGDERKTAAEDTMLAYKAAQDIAAADMAPTHPIRLGLALNFSVFYYEILNSSDKACNMAKQAFEEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQEQMDEA
What is the function of this protein?
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes (By similarity).  Specific negative regulator of slow-vacuolar (SV) ion channel.  Mediates F-actin dynamics possibly through inhibiting ADF1 phosphorylation (PubMed:26345162).  Negative regulator of freezing tolerance that modulates cold-responsive C-repeat-binding factors (CBF) DREB1A and DREB1B proteins stability by facilitating their ubiquitin-mediated degradation when activated by CRPK1-mediated phosophorylation in freezing conditions (PubMed:28344081).
What are the official names of this protein?
14-3-3-like protein GF14 lambda, 14-3-3-like protein AFT1, 14-3-3-like protein RCI2, General regulatory factor 6.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Cytoplasm. Note=Translocates from the cytosol to the nucleus when phosphorylated by CRPK1 in response to cold stress.
Protein: MUTL_RHORT
Sequence: MTIRLLPPVLVNRIAAGEVVERPASAVKELVENAIDAGASRIDITMTDGGRARILVVDDGRGMDPGELSLAVERHATSKLPGDDLLDIHTLGFRGEALPSIGSVARLTLTSRAAGAGDAWALTVEGGAKGEPEPASHPQGTRVEVRDLFYATPARLKFLKAPRTEQMHAVDVVHRLAMAHPAVGFTLSDGTRQQIRLSGAQGELFEARLTRLGAILGREFSDNAIAIEAEREGIRLTGHAALPTYNKATSAGQYLFVNGRPVRDKLLHGAVRGAYQDVLAHDRNAVLALYLDLPPEMVDVNVHPAKAEVRFRDPGLVRGLIIGALRHALAAAGHRASSTVSLAALGALRPAQGSGAPALPWGAGGYGGGASHPGLEERRSAYAAQAPAGTPDPWAGRGMGAGGGSGQAAMAWLAGAPPAAPRLAGEPEAPPTGAEDFPLGAARGQIHDTYIIAQTRDGVVIVDQHAAHERLVMERMKAALAERGEVARQILLLPEVVELDEPGAVRVATAAAELAKLGLVVEGFGPGAVVVREVPALLGDTDVKGLVADLAEGLAEWGTAQALEDRLGDVVATMACHGSVRAGRRLRIEEMNALLRDMERTPRAGQCNHGRPTYVELRLGDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: FAR7_DELRA
Sequence: TPGQDFMRF
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
FMRFamide-like neuropeptide TPGQDFMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_DEHM1
Sequence: MQRGDGRNFNQLRPITITPGFQSFAEGSVLIEQGKTRVICSVSMEDKVPQFLRNSGTGWVTAEYSMLPRSTVTRTQRDSSAGKISGRSQEIQRLIGRSLRSCVDLAALGERSFIIDCDVIQADAGTRTASITGAYIALYLAFKKMVDMGILSKMPFTSQVAAVSVSIFKGNIVLDPCYDEDFQAEVDFNLVMNDRAEFVEIQGTAEGKTFSRDTLDQVLKLGEAGIWQLFDIQNSITRP
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ACCD_KLEP7
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLYAMPVVAAAFEFSFMGGSMGSVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPVAVSEAPHEGVVVPPAPDQEPEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.