PharMolix/UniProtQA huggingface dataset:
Protein: RL13_SALTI
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: YAE5_YEAST
Sequence: MDTVRLSHLVLQEGINHTMALWKFQAFELFTDHLNPEMCLSRDISLYTSMALMLVRIVVEAKRKVLVIWKAAFQSLQDGTCHGTICAHCSLEHYSLSTFVCC
What are the official names of this protein?
Putative uncharacterized protein YAL045C.
Protein: GUAA_BRUA2
Sequence: MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGIPVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPYAVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAALLAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALEGESDPEKKRKTIGRLFIEVFEEEARKLGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: LYAR_RAT
Sequence: MVFFTCNACGESVKKIQVEKHVSICRNCECLSCIDCGKDFWGDDYKNHVKCISEDQKYGGKGYEAKTHKGDVKQQAWIQKINELIKKPNVSPKVRELLQQISAFDNVPRKKAKFQNWMRNSLKVHSDSVLEQVWNIFSEAASSEQDQQPPSHMAKPNTEVPTKVPSTKTNGTTEEQTEAKKNKRERKEERQKSRKKEKKELKLENHQENLKGQKPKKRKKGQEAGHEAGGEDAAEANGAPEKKRARDAQASEEGADRNGGPAEDADEGPTKTAAGKRKRQKHSEVESDNKKKKMKLPGQPEEGEPEDHEAPSKGKFNWKGTIKAVLKQAPDNEISVKKLKKKVIAQYHAVMSDHHTSEEELLAIFNKKISRNPTFKVLKDKVKLLK
What is the function of this protein?
Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs.  Also acts at the level of transcription regulation.  Along with PRMT5, binds embryonic globin promoter (By similarity).  Represses the expression of embryonic globin Hbb-y gene (By similarity).  In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41.  Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (By similarity).  Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (By similarity).  In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (By similarity).  Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells.  Prevents NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (By similarity).
What are the official names of this protein?
Cell growth-regulating nucleolar protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Cell projection, cilium, photoreceptor outer segment. Note=Component of pre- ribosomal particles, including pre-40S, pre-60S and pre-90S (By similarity). Associated with cytoplasmic ribosomes, but not polysomes, as a component of the 60S subunit (PubMed:24990247). In the retina, predominantly expressed in photoreceptor outer segments. In the nucleolus, colocalizes with nucleolin/NCL, therefore may reside in the dense fibrillar component (DFC) (By similarity).
Protein: ALLA_PSEPF
Sequence: MRTLTIEPLTKEAFAPFGDVIETDGSDHFMINNGSTMRFHKLATVETATPEDNAIISIFRADAQDMPLTVSMLERHPLGSQAFIPLLGNPFLIVVAPLGDVPVSGLVRAFVTNGRQGINYHRGVWHHPVLTIEKRDDFLVVDRSGKGNNCDEHFFKEDERLILAPHQ
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: RL20_ARTS2
Sequence: MARVKRAVNAHKKRRVILERAKGYRGQRSRLYRKAKEQLLHSFVYSYGDRKKKKGDFRRLWIQRINAASRANGLTYNRLIQGLKAAEVEVDRRMLAELAVSDANAFAALVQVAKDSLPADTSAPAVSAEAAPKAKAAKKPAAKKAAAKKPVAEEAAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: WDFY2_CAEBR
Sequence: MAAIINQRVDQGESSMGGAKPTLLHKIAGHVARINDVILLSKDEGVWTASDDRSVRLYLKRDNDQFWPSIHHFMPVAPTCLFYSEETYKLLVGLINGNVYEFNVADDFNSMTESRKWTCHAGPISGLGFALSSELIFSCSRDKSIVWHCSENSNKVGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIIDNQPNLVSKLSAHTNSITSLTWDGNKKVLYSGSSDHLIIMWDIGGGKGEAYELNGHNGKVTTLCAAPAAKRLFSADEHGKLMCWDMDVRRVETPEWKTSDCCQKCNQPFFWNLQAMWQRKVVGLRQHHCRTCGSAVCGSCCDNWTTYPPMGYETKVRICNDCAGRMKENPGNFDLTPLAIPHEIRTGITAMHLQETLGLLVTSGQNRVVMIWDVRSVCSAPSGSGGH
What is the function of this protein?
Plays a role in coelomocyte endocytosis.
What are the official names of this protein?
WD repeat and FYVE domain-containing protein 2.
Protein: GL6D1_HUMAN
Sequence: MNSKRMLLLVLFAFSLMLVERYFRNHQVEELRLSDWFHPRKRPDVITKTDWLAPVLWEGTFDRRVLEKHYRRRNITVGLAVFATGRFAEEYLRPFLHSANKHFMTGYRVIFYIMVDAFFKLPDIEPSPLRTFKAFKVGTERWWLDGPLVHVKSLGEHIASHIQDEVDFLFSMAANQVFQNEFGVETLGPLVAQLHAWWYFRNTKNFPYERRPTSAACIPFGQGDFYYGNLMVGGTPHNILDFIKEYLNGVIHDIKNGLNSTYEKHLNKYFYLNKPT
What are the official names of this protein?
Putative glycosyltransferase 6 domain-containing protein 1, Galactosyltransferase family 6 domain-containing 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: MOAA1_MYCTU
Sequence: MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIEPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase 1, Molybdenum cofactor biosynthesis protein A 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TGT_NITEC
Sequence: MKFQLHCHDHHARRGTLTLAHGMIETPAFMPVGTYGAVKGLSPDELQTLGAEIILGNTFHLWLRPGLEVIEAHGGLHRFMHWDGPILTDSGGFQVFSLGALRKISEEGVRFRSPVNGDTCFLTPEESMRIQRVLNSDIVMIFDECTPYPVDMQIAEDSMQLSLRWAERSKAAHAGNPNALFGIVQGGMYESLRDRSIAGLYNIGFDGYAIGGLSVGEPKLEMQRILSHTAPQLPVDKPRYLMGVGTPEDIVRAVEQGIDMFDCVLPTRNARNGWLYTSQGVLKLRNSRYRLDTSPPDENCDCYTCRHFTRAYLHHLQRTGEMLGARLNSLHNLHYYQRLMSDIRKAIEAGQFEQFACRFSG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PS1C2_MOUSE
Sequence: MLTWKLLGLLVLCLCAGGISGNGDPSPGSTDTHEEEDSPPLPLGPPIPGDPWPGAPPLFDEPPPPGSNRPWRDLPDSGAWPPKPPSTDPPKPPLPDDPWPAGTQPPENPWPPAPEMDHESQEEPDLDPPQEEYR
What are the official names of this protein?
Psoriasis susceptibility 1 candidate gene 2 protein homolog, Protein SPR1.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_XANAC
Sequence: MTASAPAASASARLLDGRRIAEELLDGLKLRVDARVAAGKARPGLAVVLVGGDPASSVYVRNKRRAAEKVGIEAFDYDLPQGTSEAQLASLIDELNADPKIHGILIQLPLPGIPDANRLIQRIDPRKDVDGFHPQNVGHLALREFGLRPCTPRGIVTLLGHTDQPVRGRNATIVGVSNHVGRPMGLELLIAGCTVTSCHKFTPPDVLEASVRNADILVVAVGRPGLIPGEWVKPGAVVIDVGINRLDDGRLVGDVGFDAAAQRAAWITPVPGGVGPMTVATLMQNTIEAADAAGIQDSGFGIR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y654_CHLPN
Sequence: MLKKKPVSFSCIDGHIYKIFPNDLNANNTVFGGLLMSLLDRLALVVAERHTESVCVTAFVDALRFYAPAYMGENLICKAAVNRTWRTSLEVGVKVWAENIYKQERRHITSAYFTFVAVNEDNQPIPVHQIVPETPEEKRRYNEADRRRQARLELK
What are the official names of this protein?
Uncharacterized acyl-CoA thioester hydrolase CPn_0654/CP_0093/CPj0654/CpB0680.
What is the protein family that this protein belongs to?
Belongs to the acyl coenzyme A hydrolase family.
Protein: TXND2_RAT
Sequence: MFKKNQKLSKDKGLEVNSVQAGAPEESDVKLNNGGKANERGSNEFLDTAQSKEKVIASVVGNMLHMSTEESEPPQQVSSTSMFSENTIYPKHEGSPKSSTKNTQLKQEDISKTSSYSKQTNSSNIPKSLAITTYPKQGSTLKPAANGTHDREAEKPKSSEDLIQSKKGDIFKPSEDSIQSKKGDMPKSSEDPIQSKKDDTAKSLEDTIQSKNGDMPKSSEDPIQSKKDDTARSLEDSIQSKKGDMPKSSDTIQSKESETPKFLQDTIQSKGGKINKQVKDSMKSKESKIRKPLKDSIQSKENKIPKSSQDSAQPKEGKIHKPLKDSLPSKEGDISKPSEDTIQAKEEITVSPEDTIQAKEEITMSPEDTIQAKEEITVSPEDTIQAKEEITVSPEDTMQSKEEITVSPEDTVQSQEGDIKSSEDVQPSENEIFPFEAEIETLEEGMVRVIKDKEEFEEVLKDAGEKLVAVDFSAPWCGPCRKMRPHFHSLSLKHEDVIFLEVDTEDCEQLVQDCEVFHLPTFQFYKNEEKVGEFSGALVEKLEKSIAELK
What is the function of this protein?
Probably plays a regulatory role in sperm development.  May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis.  May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents.  Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein 2, Spermatid-specific thioredoxin-1, Sptrx-1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_PSEAE
Sequence: MGHSVAGVCLEEPAVLTAFPSLLHPQDPPQQRDRILFVTAELSDFVKVGGLGDFSAALPRVLKREHSVRVLLPGYRQVLERCRDLRIIGSLPGRAAIPPCEIGLVTLDDGLEVMLVLCPLLYEREGTPYMDDQGNDWPDNHLRFARLCLAAAEIAGGRGAQGWQPGLVHANDWPSALTPAYMAWNGVRTPSLFTIHNLAYQGLCDLQCSAELGLPDEALSHESMEFHGRLSFLKAGIAHAHHITTVSETYAQEITTPEYGCGLHGILKYKVEKRQLSGIVNGIDDSWQPHCDPHLVACFSARQWAGKRANTRYVEERFGLEPGKGPLFAVVSRLVQQKGIDLTLEISDALLQAGGRLVSIGRGEPNLEKAMLELARRHPGQVGVHIGFDETEARRIYAGSDFLLMPSRYEPCGLSQLYAQCFGSLPIARCTGGLADTIVDGVTGFLFREETAQSYLDAVMRAINVYHCPSLLNAMRCKAMAAPMFWSDSVEPYNRLYRRLLRNTAPALRGVRQ
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: GLCE_ECOLI
Sequence: MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQTLDVRCHRGIVNYDPTELVITARVGTPLVTIEAALESAGQMLPCEPPHYGEEATWGGMVACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMVGSYGCLGVLTEISMKVLPRPRASLSLRREISLQEAMSEIAEWQLQPLPISGLCYFDNALWIRLEGGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQLIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQLDPCGVFNPGRMYAEL
What is the function of this protein?
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate (PubMed:4557653, PubMed:8606183).  Is required for E. coli to grow on glycolate as a sole source of carbon (PubMed:8606183).  Is also able to oxidize D-lactate ((R)-lactate) with a similar rate (PubMed:4557653).  Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown (PubMed:4557653).
What are the official names of this protein?
Glycolate oxidase subunit GlcE, Glycolate dehydrogenase subunit GlcE.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Glycolate oxidoreductase activity was shown to be firmly associated with the cytoplasmic membranes.
Protein: RS12_CORDI
Sequence: MPTIQQLVRKGRHDKTAKVATAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGIEVSAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGALDTQGVKDRKQARSRYGAKKEK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CATA_CAPAN
Sequence: MDLSKYRPSSAYDSPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYHLIEKLATFVRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVICRFSTVVHERGSPESIRDIRGFAVKFYTREGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQENWRILDFFSFLPESLHTFAFFYDDVCLPTDYRHMEGFGVHAYQLINKAGKAHYVKFHWKPTCGVKSMTEEEAIRVGGTNHSHATKDLYDSIAAGNYPEWKLFIQIMNPEDVDKFDFDPLDVTKTWPEDILPLMPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGVYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCAHHNNHRDGAMNFMHRDEEVDYLPSRFDPCRPAEQYPIPSCVLTGRREKCVIPKENNFKQAGERYRSWAPDRQDRYINKWVESLSDPRATHEIRSIWISYLSQADKSCGQKVASRLTVKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase, CaCat1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RL32_ACISJ
Sequence: MAVQQNKKSPSKRGMHRSHNALTVPGIAVEPTTGETHMRHHISPNGFYRGRQVLKNKSEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ADEC_CERS5
Sequence: MRRSLSDLIDQGRGKAPADLVLKNGRIFDLVTGELVQTDVAICGDRIVGTFGTYEGRREIDCRGRILVPGFIDTHLHVESSLVTPFEFDRCVTPRGITTAICDPHEIANVCGLEGIRYFLEAAEHLVMDLRVQLSSCVPSTHMETAGATLEAADLVPLMDHPRVIGLAEFMNFPGVLAKDAGCLAKLEAFRGRHIDGHAPLLRGKDLNGYIAAGIRTEHEATTAEEALEKLRKGMRVLIREGSVSRDLEALVPLLTERHSPYLCLCTDDRNPLDIAEHGHIDHMIRTAIRLGAPPLAVYRAASLSAAEAFGLKDRGLIAPGKRADVVALDSLEGCHAGLVVAGGVVVDAGAFAARGTVEPVARASVRVAPVEAAAFRCPGNRAETPVIGILPGKIITEHLTDAIEPVDGDKRPDPSRDLARIAVIERHGRNGGRAVGFVRGFGMRRGAIASTVCHDHHNLAVVGVDYADMALAANRLREIEGGFAVAAEGEILAELALPVGGLMSLRPFEEVRDALVALREAARGLGVTLEEPFLQLAFLALPVIPHLKITDRGIVDVDRFEILP
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: YH6B_SCHPO
Sequence: MIAKSFIASFLFLCFAFSGVKADGCSEENGYYYCNQASEVEFTNVGYSSTYNEITNMDTSSCSCSSTPKSYGGNLAPFDEEFSFHFRGPIELKRFAVYYPDTSNALSSLRKRSNNQHMKRHPHHKRDDVIDSTLTVYETVMYTTAVYGDSATTPAASEAQASSDILSSLASLSSASTDNLAASVTPTTVAASVASSVDTDSASATISSVVDSATSSVSTVIPSSIISAAPPDSASESTPASTSYASSTTSATSTSTTSGSSGSSDWGRSSFYEADSGTSDNIVFLNNMGGSAGSGVWSSCFGNSLSFAASNGVDGASSSQVLENILVASDKEFSIWTATECNNDCGYYLPGIPAYHGFSGAKLVLMEFIMPHDSSSSYNQDMPAIWSLNAQIPRTLQYGNADCSCWTTGCGEFDIFEVLSTGNEKMIPTLHGSQGSSNGNGGGAGSSDYFARPTSSSMIGAVIYDTSSSGIYIIDVTDQNVSFDSTYSASDVDAWLQSGATIVQLSS
What are the official names of this protein?
Uncharacterized serine-rich protein P23A10.11c.
What is the protein family that this protein belongs to?
Belongs to the PGA52 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COXX_PROM9
Sequence: MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGALNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTLAASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKNIVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLATVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFGICLLLLISRTQLSVEFEQQSMQIFFSIGSLLSN
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2503_LACPL
Sequence: MGILIALIPAIAWGSIGLISGRMGGTARQQTLGMTMGALVFGLALWAVEQPTLTSKIWLIGIVSGLFWSIGQGQQFTSMKAVGISRTTPISTGMQLVANALAGVLLFNEWHGNMYWIGSASVIVLIAGAVLTSLTDKTDPNRSASENWGVGIRALILSTIGYAGYTIVVHYGNVNAQAVVMPQAVGMLLGALIWSFKDKPWVVKATYRNIVTGLVWGIGNLFMFMAMAQIGQAVAYSLSQMGIVISTFGSIYLLGEHKTKREMVYVVIGSILVIVGGVALSLMKA
What are the official names of this protein?
Putative sugar uptake protein lp_2503.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCTA_ECO45
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y975_STRP2
Sequence: MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLVLVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
What are the official names of this protein?
UPF0758 protein SPD_0975.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: HEMJ_RICPR
Sequence: MESYYLWFKSAHLISAICWMAGLLYLPRIYVYHTKAKIGSELDSTLQVMELKLLRFIMNPAMISTFIFGLINAHIYGFVALDTWFQFKMFAVLILVIFHGLLARWRKDFAKGKNVHSKKFYRIVNEIPAICMVIAVIMVIVKPFD
What is the function of this protein?
Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.  Is involved in the biosynthesis of tetrapyrrole molecules like heme.  Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone.
What are the official names of this protein?
Protoporphyrinogen IX oxidase, PPO.
What is the protein family that this protein belongs to?
Belongs to the HemJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FCF1_YEAST
Sequence: MGKAKKTRKFGLVKRTLNTKKDQRLKKNQENIKTKEDPELTRNIPQVSSALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIVRGMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCSHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVGGHAYVIEKLPDVF
What is the function of this protein?
Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly.  Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites.
What are the official names of this protein?
rRNA-processing protein FCF1, FAF1-copurifying factor 1.
What is the protein family that this protein belongs to?
Belongs to the UTP23/FCF1 family. FCF1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FEN1_OSTTA
Sequence: MGIKGLTALLSENAPGAMREQKFTSYLDRRVAIDASMHIYQFMIAVGRTGEQTLTNEAGEVTSHLQGMLMRTSRMLEAGIKPVYVFDGKPPTMKGGELAKRKDKREEAEAALKAAREAGNQEEVEKLSKRTVRVSKEQSMEVMKLAQLLGIPAFEAPCEAEATCAAMCKAGLVWAVGTEDMDTLTFAAPRVARNLMAPKSAEKPVLEFDYEKTIAGLGLTADQFIDLCILCGCDYTDTIRGVGPKTALKLIKEHGSIEKILEAIDTEKYPPPKDWEFAGARELFKNPEVMDVSGINLSWKAPDEEGLVEFLVKEKQFQEDRVRGVCARIRKARQGAASQNRLESFFGPPKIISSTIGKRKVEETKSGKGSKAGLNKKSKGVSGYKSKKT
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RPA34_MOUSE
Sequence: MAGTQACSATRFSCPPHFTEMSPDSEPSRFSLEALTGPDTELWLIQAPADFAPQCLNGRRVPLSGSKTVKGKLDGKKHRYRVFTSSPQAREATLLASSSEAGGRLTCAPAPSGSLRIMEGPQEYLLSRVPLQLIPTSLPPQIPAGLRPRFSAFGGSPPVTGPGSASALRSPTSGKRKSTRKGTDASSDTQEAVNRHGAMEVKTALGNLGVSVKKRKRYFMQEEMEAKTMEPVAELPVPSATSSKKRKKSKGTETSQVEHTEPVAQTEPPEGTFLFPTKKRKRQKEADGTEEVDGIVADSQPQVIVEAQEETILLSPTKKRRKEKRQNLGMEAEMGPPGVLMVTEHSEHGLQAEVALVSPKKTKKKKGKRVGETEAALPDDFEPQGALAPSKKKERGARL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Involved in UBTF-activated transcription, presumably at a step following PIC formation.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA34, A34.5, DNA-directed RNA polymerase I subunit G, RNA polymerase I-associated factor PAF49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA34 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Accumulates in the nucleolus of exponentially growing cells.