PharMolix/UniProtQA huggingface dataset:
Protein: AAT1_MEDSA
Sequence: MASQNITPSPTASSDSVFAHLVRAPEDPILGVTVAYNKDPSPIKLNLGVGAYRTEEGKPLVLDVVRRVERQLLNDMSRNKEYIPIVGLADFNKLSAKLIFGADSPAIQENRVTTVQGLSGTGSLRVGGEFLAKHYHQRIIYLPTPTWGNHTKVFNLAGLTVKTYRYYAPATRGLDFQGLLEDLGSAPSGSVVLLHACAHNPTGVDPTLEQWEQIRQLIRSKSLLPFFDSAYQGFASGSLDADAQPVRLFVADGGELLVAQSYAKNMGLYGERVGALSIVSKSADVSSRVESQLKLVIRPMYSSPPIHGASIVAAILKDRDLYNDWTIELKAMADRIINMRQQLFDALRARGTPGDWSHIIKQIGMFTFTGLNPEQVSILTKEYHIYLTSDGRISMAGLSSKTVPHLAHAIHAVVTRVA
What is the function of this protein?
Important for the metabolism of amino acids and Krebs-cycle related organic acids.  In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism.
What are the official names of this protein?
Aspartate aminotransferase 1, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNP9_ECOLX
Sequence: MPRRLILSATERDTLLALPESQDDLIRYYTFNDSDLSLIRQRRGDANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQVQAEPASWAKYGERDVTRREHAQELRTYLQLAPFGLSDLPALVRELTELAQQTDNGLLLAGQALESLRQKRPILPALSVIDRACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRHMLEHIERLKTFQLVDLPEGLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAVVLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAMNDKVRLYSRIGQALLEAKESGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEVLEPRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRKFYEICALSELKNALRSGDIWVKGSRQFRDFDDYLLPAEKFAALKREQALPLAINPNSDQYLEERLQLLDEQLATVTRLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRIKITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTYAKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTGHVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTDTAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAHWDDILRLASSIKQGTVTASLMLRKFGSYPRQNGLAVALRELGRIERTLFILDWLQSVELRRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP
What is the function of this protein?
Required for transposition of transposon Tn1721.
What are the official names of this protein?
Transposase for transposon Tn1721.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.
Protein: ITPA_TUBMM
Sequence: MPQTLFFVTSNASKLAEVSAILAASGISVQSMALDLPELQGSIEDISKDKAKRAAEAIGGPVLVEDTCLCFNALKGLPGPYIKWFMKDLGHEGLVNMLAAYEDKSAQAVCTFAHCEGPGKEPVLFQGRTDGKIVPPRGPAKFGWDPIFEYEGQTYAEMDKAAKNLISHRFKALEMLKEWMEAHP
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDH_ACISJ
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDCAFPLLAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQLAAKGGFKVGDIKKLTVWGNHSPTMYADYRFATVDGKSVKDAINDPAWYKDVFLPTVGKRGAAIIAARGLSSAASAANAAIDHMRDWALGSKGEWVTMGVPSNGEYGIPAGIVFGFPVTTENGEYKIVEGLPIDAFSQECIDKTLAELQGEQDGVKHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: THIT_LACP3
Sequence: MQQHKQLVVILETAIIAAFAMALTYIPHTTGVSAIELNYGLIPIAVLAMRRGLVPAAWAGFVWGILDLILRGIGGGSVLNPLQGILEYPIAFTLVGLMGLTFASFQKAVRGSEKVKASGYAFAGIIIGTFAKYFIHFIAGVVFWGAYAPKGTNVWVYSLIVNGGSALFSTVLTIVVVGVLLTVAPQLFVAKDGKSFSTKAA
What is the function of this protein?
Thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins and transport it into cells.  Binds thiamine with a dissociation constant of 0. 5 nM.  Upon coexpression with its energy-coupling factor (ECF) ABC-transporter complex EcfA1A2T in Lactococcus lactis subsp.  cremoris (strain NZ9000) allows thiamine uptake; uptake requires both ThiT and EcfA1A2T.
What are the official names of this protein?
Thiamine transporter ThiT, Thiamine ECF transporter S component ThiT.
What is the protein family that this protein belongs to?
Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Thiamine transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPB_ENTFA
Sequence: MNIEKMTTTLQEAIAEAQKVAVTRQHQEIDIAHLWKIFLQPNHFGRNFYTDAGLDVDAFEREVDNALDEYPSVAGGNVQYGQNLSQNLFHLLQEADSLREEFQDEFLSTEIVLLALMKLKNYRLTKYLMQQGITEKELRKNIEEMRGGDRVTSQNQEEQYKALEKYGVDLVQQVKAGKQDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGKIILFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERRFQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKAIDLVDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLANLQEELADLREEANSMKMQWETEKEEVNAVSNKRAEIDKAKHELEDAENNYDLERAAVLRHGTIPQLEHELKELEEKNAKDNVKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLMKLNETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEDLFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEIEKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTPEGTIPEEVENQVMNILKGHFKPEFLNRIDDTILFTPLSLDNVKGIIGKMTAQLAHRLEQQEIVLEITDEAKTWIAENGYEPAYGARPLKRFITREVETPLAKEIVSGRVMPKTKVTISLLDNQLVFENEPIEEV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_LEPBP
Sequence: MQNKIQGVYLVTDRPLCLHHKLEEVVQMAASGGVSLVQLREKDSTSREFLELAIHLKFILSPFQVPLLINDRVDLCLASGADGVHLGQTDLPWLEARRILGKDAIIGLSIETKEDFATLTKEDPNPQLEYLAVSPVFDTPTKTNTKEALGLAGVRWLKEKTDIPVVAIGGINISNAKDVIGAGADMIAVVSAICSAKNPKEATVALRNQF
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PRIC2_MOUSE
Sequence: MVTVMPLEMEKTISKLMFDFQRSSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNSAGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQIKGGDIAVFASRAGHGICWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMRHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEAMLNQHSQLQVSSNRLSADVDPLSVQMDLLSLSSQTPSLNRDPIWRSREEPFHYGNKMEQNQSQSPLQLLSQCNIRTSYSPGGQGAGAQPDMWAKHFSNPKRSSSMALKGHGGSFIQECREDYYPGRLMSQESYSDMSSQSFNETRGSIPVPKYEEEEEEEEGGISTQQCRPRRPLSSLKYTEDMTPTEQTPRGSMESLALSNATGLSAEGGAKRQEHLSRFSMPDLSKDSGMNVSEKLSNMGTLNSSMQFRSAESVRSLLSAQQYQEMEGNLHQLSNPLGYRDLQSHGRMHQSFDFDGGIASSKLPGQEGVHIQPMSERTRRRTTSRDDNRRFRPHRSRRSRRSRSDNALHLASEREVIARLKERPPLRAREDYDQFMRQRSFQESLGQGSRRDLYSQCPRTVSDLALQNAFGERWGPYFTEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSDELLHKYSSYGVPKSSTLGGRGQLHSRKRQKSKNCIIS
What are the official names of this protein?
Prickle-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Nucleus membrane.
Protein: ISPT_CHLAB
Sequence: MSLTLKQADQASLSMQSLPKHVAIIMDGNRRWYRQHQAQCSIKSSSGHYYGAKVLPNIIESAFSLGIEVLTLFAFSTENFLRSAEEVAELFSLFHAQLDEQLPYLIENKIRLRCIGNLLALPPDLQQQIAKVASETQRHGMRELVLAINYGGKDELVRAFKKLHHDLVNKKISLDSVSEELIRLYLDTSEIPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFKPYHLLDAIKAYQHRSRRGGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CYSG_XYLF2
Sequence: MTANVLFPLFANLHDRAVLVVGGGKVAERKTEALLKVGALPIIGAPSLTASLQRWAETGRITWRQGTFENSWLQEDIWLVIAATDQPEVNHAAARAAHAQRLFVNVVDDIALSNVQVPAVVERGPLRIAISSGGGAPMVARYLRQQLESLIDDSWGRLTTLFAQRRDTIRARYPNIEARRRFFETQLAGPLQRLLRKQRHAEAEAVLEAALAKTPPTESGSVTLVGAGAGDAGLLTLNALRALNEADIILYDRLVSDTVLQMARRDAEQIEVGKSATGHSVRQEDIHTLMLQHARAGQRVVRLKGGDPFVFGRGGEELEFLRTHGIPYEVIPGITAALACAAYAGIPLTHRDHAQSLCLITAHCQSSLDTLNWAALAQERQTLAFYMGVAGLPTIQQRLCEAGRTETTPFALIENGARAQQRVLTGTLKTLAHTAQTYAVRPPALLILGEVTALAEHLHWFGTTPLSAPCPPRTHPIS
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: ATP5J_BOVIN
Sequence: MILQRLFRLSSAVQSAISVSWRRNIGITAVAFNKELDPVQKLFVDKIREYRTKRQTSGGPVDAGPEYQQDLDRELFKLKQMYGKADMNTFPNFTFEDPKFEVVEKPQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.  Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
What are the official names of this protein?
ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6, ATP synthase peripheral stalk subunit F6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase subunit F6 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: RSMA_YERPA
Sequence: MNNRVHQGHFARKRFGQNFLNDQFVIDSIVSAIHPVPGEAVVEIGPGLGALTEPVAARMDHMTVIELDRDLAARLASHPQLKDKLTIHQQDAMKVNFSELSEQAGQPLRVFGNLPYNISTPLMFHLFSYTDAIRDMHFMLQKEVVNRLVAGPNSKTYGRLTVMAQYYCNVIPVLEVPPTAFTPAPKVDSAVVRLIPHVQMPHPVGDVRMLSRITTQAFNQRRKTVRNSLGDLFTSEQLIELGIDPILRAENISVAQYCKLANWLSAQSTPQK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_SHEPA
Sequence: MIYGSIVALVTPMNSDGTVDYKSLESLVEYHIAQGTDAIVAVGTTGESATLPAKEHIAVVEQTVKFAAGRIPIIGGNGANATAEAVELTKGLSNVGVAAMLGVTPYYNKPTPKGLIAHYTAVAASTDVPQILYNVPGRTAVDMRPETVAQLVGIKNIIGVKEATGDLSRVKELRNLCGDDFLLYSGDDATAREFLSLGGNGVISVANNIVPKQFKAMCDAALSGDVSAALSAEESIKELFSVLFCEANPIPVKWAVHRMGLISNGTIRLPLTELSTEFHGLLLEAMKNARIEVK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_BACAN
Sequence: MSTVVRIPRSVSWKGDAIAVLNQTKLPHSTEYKTLTTIEEVWKSIVMLEVRGAPAIGIVAAFGLALASKKYTTLHIEEFQKKFNRDCNYLGTSRPTAVNLFWAIDRMRESIQEITTIKEAQKILEEEALRIQQEDEAVCRSIGEHALTCFKDGDNILTICNAGSIATARYGTALAPFYIGKEKGVRLHAYACETRPVLQGGRLTTWELKQAGIDVTLITDNTAAHAIQTKEISAIIVGADRIVANGDTANKIGTMNLAILAKYFDIPFYVAAPLSTFDITKQTGAEIVIEERDETEVTKIFGKQVAPVGTTVYNPAFDVTPNELITGIITEKGIIRGDYKREIASLFKKTS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: ACKA_BUCAP
Sequence: MVKILNNLIFVLNCGSSSVKFAILNPDNKKKYLSGLVECLFLSKTYMKWKDLTTEHKKCIGSNLSHKDALNFIFNKFFLEKKDIYKNIVGIGHRVVHGGNKIKSSTLIDDNIIQLIQKAISFAPLHNPANLIGIKTAIEKFPIFAKKNVAVFDTSFYQNMPETSFLYAIPYFFYKEHHIRRYGAHGTSHHYVASEVALILNKNFNSLNVITCHLGNGASVSAVCNGICVDTSMGLTPLEGLVMGTRSGDIDPSIIFFMYQKLGMSIDEIHTILTKESGLLGLSGISSDFRYFEKKYYFEKKARLAVDIFCHRLSKYIASYMSLMENNLDAIVFTGGIGENVPLIREITLSKLLLIGFKIDTQRNLGIKNGKHGLITTDKSRPAFVIPTDEELAIAQETIKIIK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYUA_HUMAN
Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
What is the function of this protein?
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (PubMed:28288128, PubMed:30404828, PubMed:20798282, PubMed:26442590).  Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (PubMed:28288128, PubMed:30404828).  Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (PubMed:30404828).  Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (PubMed:20798282).  This chaperone activity is important to sustain normal SNARE-complex assembly during aging (PubMed:20798282).  Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (PubMed:26442590).
What are the official names of this protein?
Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
Protein: VF229_IIV3
Sequence: MEQQSENVYFSGSESESLSDSESRAQPQNQNSDNSRSASLTPPDSSDLEDYVDSDSETSSSLVNAPKRIKIIRSPSTSNWPRRLTSDDNGSDDDSEDEDESNDEQDLVESEEEDQRSRSSSRSAMDISSEEDSGDDEPSFTLTELPGDVPDFKVYNRNIAIFSIKYLNQFGRLNAGIQETDFPTAKLVNTNRHVVVWINMLENDTTPVTPDSFDSFNLSGAIILKDSSGLIEYMYVHKNSRTVKSLLLDAIATIYNQVTGNDILINIWTQNINIDEDVRFLVNYGFVEPAIVGKNTIQMKYHPKIPHQQTLNEIRRLLGYSKRNVGWINVFLPKDLAIKLFSYVNNYDVEFGGYLPLTSVQKPNGAWVLGWDDTLVSKGESLSVYIPPPQEHQKLEETIIGFHTHPIALSSSNTISDGMVILPPSNIDLKGISNQWLFPRPNIAHFICSPEGLWVVSLTEEFQSLLMGLRDLGEVAWPCINMILFVIFESMFQQHDQKFNYPTVTPITKWFELTDVQDLIKNLTLKRCFNYLNIPMEKFEATCQTISGYQNVRLYDISYNKWESFSALPDEGLYFTFYYKYDDFTGYPRQKSLTTEASN
What are the official names of this protein?
Uncharacterized protein 229L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 229L family.
Protein: QUEF_VIBVU
Sequence: MSKYSDAKELAGLTLGKKTDYANQYDPSLLQPVPRSLNRDDLQLGDELPFMGHDIWTLYELSWLNSKGLPQVAVGEVYIPATSANLIESKSFKLYLNSYNQTRFDSWEEVRQRLITDLSHCAGEAVEVAVNSVTHYTQQPIVTMEGECIDEQDIDISSYDFDDRLLEGAAGEEWVTETLHSHLLKSNCLITNQPDWGSVEIRYQGHKIDREKLLRYLVSFREHNEFHEQCVERIFTDLMKYCQPESLTVFARYTRRGGLDINPYRSTEQAKPDHNHRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_HAEDU
Sequence: MAYSYSEKKRIRKSFGKRPQVLNVPYLLTIQLDSYEKFIHRDLDGQQGLEAAFRSVFPIVSNNGSTELQYVSYELGEPVFDVRECQIRGTTYAAPLRVKLRLVAFDREAAAGTVKDIKEQNVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYARIDRRRKLPATIILRALGYTTEEILTMFFEKVLFEIQDNKLLMILVPERLRGETAAFDIEANGKIYVERGRRITARHIRTLEKDGITQIEVPVEYIVGKVAAKDYVDLSTGELVCPANTEISMDMLAKLSQAGYKELEVLFTNDLDHGPYISETLRVDSTYDRLSALVEIYRMMRPGEPPTKEAAEALFDNMFFSADRYDLSAVGRMKFNRSLNIPEGVGTGILTNDDITGVMKKLIEIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVRERLSLGDLDGITPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLSVYARTNNYGFLETPFHKVVNGQVTEEIEYLSAIEEGNYVVAQANSNLDEHFRFTDTYVTCRGEHGESGLYKPEDIHYMDISTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAIVAKRGGIIQRVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPVARGEILADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQEDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDSVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFTRVRNLLIESGVSEVNLNNVAREKWLEQTLDDEAKQNQLEQLAEQHEELCKEFERKLEIKRNKIIQGDDLAPGVLKVVKVYLAVRRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGEPVEIVLNPLGVPSRMNIGQILETHLGLAARGIGDQINAMIKQQQEVTKLREYIQKAYDLGHGSQVVDLSTFTDEEVMRLAQNLRKGLPLATPVFDGAHEAEIKGLLELGGLPTSGQITLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGTHQMEPGMPESFNVLLKEIRALGIDMELDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: VHUB_METJA
Sequence: MRLMSITIQKDACLVCYACQAECPTKAIDIDSFKVCNLCMECVKVCPTGALVEEEIEVNGKKLKRVNYLAHKCEKCGQCAEACPIGIKKVDDDFPYSKGHCVLCQKCIDVCPIEIISLPGVIDKPKKEIKPPKEPIAVTDACVGCGICVPECPVNAITLENNKAVIDKSKCIYCSICAQTCPWNAIFVAGKIPKKRRKEVKKFEVNAEKCIYCLKCVEVCPGDMIKVDEENLIVIPPKSCPACKLCVNICPVDALDLEVKLSSPHPITDEGLVIVEEDFEVLKKCASVCPTEAIVVDEEKKEVRMCIVCGACTVACPTGALKLGKIEHNGKEYNRIEFSPYLCDKCGKCVEVCPMKTLRLSRGKLPLKGYCVMCLLCLSVAEKEKKGKKVLELR
What are the official names of this protein?
Polyferredoxin protein VhuB.
Protein: STO4_CAEEL
Sequence: MQRQGTVRAPCSRIVDPHQKVNYTVCGWIITIISYLVVLFTLPLSAFFCLKVVQEYERAVIFRLGRLKHGGARGPGIFFIIPCIESFKKIDLRVVSFDVPPQEILSKDSVTVSVDAVIYFRISNATVSVINVEDAARSTKLLAQTTLRNFLGTRTLAEMLSSRDAISMQMQAALDEATDPWGVKVERVEIKDVRLPIQLQRAMAAEAEAARAAGAKIIAAEGEQLASRALADAADVIATSPCAIQLRYLQTLNSISSEKNNTIIFPFPTELIAKFIQSAAA
What are the official names of this protein?
Stomatin-4.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ASSY_THEP1
Sequence: MKEKVVLAYSGGLDTSVILKWLCEKGFDVIAYVANVGQKDDFDAIKEKALKTGASKVYVEDLRREFVTDYIFTALLGNAMYEGRYLLGTAIARPLIAKRQVEIAEKEGAQYVAHGATGKGNDQVRFELTYAALNPNLKVISPWKDPEFLAKFKGRTDLINYAMEKGIPIKVSKKRPYSEDENLMHISHEAGKLEDPAYIPDEDVFTWTVSPKDAPDEETLLEIHFENGIPVKVVNLKDGTEKTDPLELFEYLNEVGAKNGVGRLDMVENRFIGIKSRGVYETPGATILWIAHRDLEGITMDKEVMHLRDMLAPKFAELIYNGFWFSPEMEFLLAAFRKAQENVTGKVTVSIYKGNVMPVARYSPYSLYNPELSSMDVEGGFNATDSKGFINIHALRLKVHQLVKKGYQK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_BOSMU
Sequence: MMAAGPRTSLLLAFALLCLPWTQVVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPGGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity).
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1A_METVA
Sequence: MAKTKPILNVAFIGHVDAGKSTTVGRLLLDGGAIDPQLIVRLRKEAEEKGKAGFEFAYVMDGLKEERERGVTIDVAHKKFPTAKYEVTIVDCPGHRDFIKNMITGASQADAAVLVVNVDDAKSGIQPQTREHVFLIRTLGVRQLAVAVNKMDTVNFSEADYNELKKMIGDQLLKMIGFNPEQINFVPVASLHGDNVFKKSERNPWYKGPTIAEVIDGFQPPEKPTNLPLRLPIQDVYTITGVGTVPVGRVETGIIKPGDKVVFEPAGAIGEIKTVEMHHEQLPSAEPGDNIGFNVRGVGKKDIKRGDVLGHTTNPPTVATDFTAQIVVLQHPSVLTDGYTPVFHTHTAQIACTFAEIQKKLNPATGEVLEENPDFLKAGDAAIVKLIPTKPMVIESVKEIPQLGRFAIRDMGMTVAAGMAIQVTAKNK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.