PharMolix/UniProtQA huggingface dataset:
Protein: BIPA_SALTY
Sequence: MIENLRNIAIIAHVDHGKTTLVDKLLQQSGTFDARAETQERVMDSNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAHGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDFPIIYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPLQMQISQLDYNNYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLTHLGLERIDSNIAEAGDIIAITGLGELNISDTICDPQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREIDGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMTMTSGTGLLYSTFSHYDDIRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRGKLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVILVPPIKMSLEQALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRGQKEE
What is the function of this protein?
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation.  Binds GTP and analogs.  Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA (By similarity).  A ribosome-stimulated GTPase, GTPase activity increases 4 fold in the presence of 70S ribosomes.  Bind to 70S ribosomes in the presence of GTP or its non-hydrolyzable analog GMPPNP; in the presence of ppGpp or under stress conditions it binds to 30S ribosomal subunits (PubMed:18621905, PubMed:19803466).
What are the official names of this protein?
50S ribosomal subunit assembly factor BipA, GTP-binding protein BipA, Ribosome-dependent GTPase BipA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=During exponential growth the GTP- bound state associates 1:1 with 70S ribosomes. Under stress conditions (induction of the stringent response, growth at 42 or 16 degrees Celsius) associates with 30S ribosomal subunits only.
Protein: ASSY_CERS5
Sequence: MSAPKKVVLAYSGGLDTSIILKWLQTEYGCEVVTFTADLGQGEELEPAREKAVMLGIKPDNIFIEDVREEFVRDFVFPMFRANALYEGLYLLGTSIARPLIAKRLVEIAAMTGADAVAHGATGKGNDQVRFELTAYALDPAIKVIAPWREWDLTSRTRLIEFAEQNQIPIAKNKRGEAPFSVDANLLHTSSEGRVLENPGEEAPDYVYQRTVDPEKAPDTPEFVEITFEKGDAVAINGEAMSPATILTRLNELGGKHGVGRLDLVENRFVGMKSRGIYETPGGTILLEAHRGIEQITLDSGAGHLKDSIMPRYAELIYNGFWYSPEREMLQALIDKSQEHVSGTVRVKLYKGFARTVARWSDHSLYSEKHVTFEEDAGAYDQKDAAGFIRLNALRLKLIATRNARVKG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAC1_HUMAN
Sequence: MKVFKFIGLMILLTSAFSAGSGQSPMTVLCSIDWFMVTVHPFMLNNDVCVHFHELHLGLGCPPNHVQPHAYQFTYRVTECGIRAKAVSQDMVIYSTEIHYSSKGTPSKFVIPVSCAAPQKSPWLTKPCSMRVASKSRATAQKDEKCYEVFSLSQSSQRPNCDCPPCVFSEEEHTQVPCHQAGAQEAQPLQPSHFLDISEDWSLHTDDMIGSM
What is the function of this protein?
May play a role in placental development.
What are the official names of this protein?
Placenta-specific protein 1.
What is the protein family that this protein belongs to?
Belongs to the PLAC1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AHPC_STAAN
Sequence: MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HABP2_HUMAN
Sequence: MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVYTQVTKFLNWIKATIKSESGF
What is the function of this protein?
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly.  It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form.  Activates coagulation factor VII (PubMed:8827452, PubMed:10754382, PubMed:11217080).  May function as a tumor suppressor negatively regulating cell proliferation and cell migration (PubMed:26222560).
What are the official names of this protein?
Hyaluronan-binding protein 2, Factor VII-activating protease, Factor seven-activating protease, FSAP, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Protein: RIR2_SHV21
Sequence: MDSVKKYLYTCDHVGFLELTKETWKNRWFPSQVPLQGDVCCVDMLNERDLEFYKFLFTFLGMAEKLVNINIEDLLSQFDSHDISHYYAEQMAMENIHGKVYANILNMLFKNNITEVYSYACDIMNDSALQEKLRWLNGRVTEASDKAEKILLFLLVEGIFFISSFFSIGLFRVRGIMNGICLANDYIARDEMLHTSAAALLYNTMTKSSERPSEDWIYKLFREAVEVEFKFIAAKGYGVSLVNVHEIRQFLQATADRILESINLNPIYGSLPPENCPLAYTSSTKSVNFFERDNSDYTGTLTNDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: LEPA_LISMF
Sequence: MNKEEMNARQKKIRNFSIIAHIDHGKSTLADRILEQTGALTHREMKNQLLDSMDLERERGITIKLNAVQLKYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVREEIEDVIGLDASDAVLASAKSGIGIEDILEQIVEKVPEPSGDVNKPLKALIFDSVFDAYRGVIANIRIMDGVVKAGDRIKMMSNGKEFEVTEVGVFSPKATPRDELLVGDVGYLTAAIKNVGDTRVGDTITLANNPAEEALDGYRKLNPMVYCGLYPIDSSKYNDLRDALEKLELNDSALQFEAETSQALGFGFRCGFLGLLHMEIIQERIEREFNIDLITTAPSVIYHVNLTDGSNIVVDNPAEMPEPGVIESVEEPYVKATVMVPNDYVGAVMELAQNKRGNFITMEYLDDIRVSIVYEIPLSEIVYDFFDQLKSSTKGYASFDYELIGYKASKLVKMDILLNAEKVDALSFIVHRDFAYERGKIIVEKLKELIPRQQFEVPIQAAIATKIVSRSTIKALRKNVLAKCYGGDVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAILKMDESK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLME_BORBR
Sequence: MAKNKFSKDWIHQHINDPYVKLAQQKGYRARAAFKLLEILDAEKLMRRGDIVVDLGSAPGSWSQVARERLAGPGGAVDGRIIALDLLPMEPVAGVEFIQGDFREEAVLEQLARMVEGQPVDLVISDMAPNLSGVGVADSARIQHVCELALEFACAHLKPNGALIVKAFHGSGFSQIVQSYKQRFKRVVERKPKASRDKSSETFLVARDLK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_LEGPH
Sequence: MNTVLKILMAGVDEVGRGPLAGAVVTAAVILKKPIDGLTDSKKLSPKQRNLLAIRIKEEALAFAYGRAEVEEIDQLNIHHATLLAMRRAVEALPIQPDNVFVDGAFTPQLNIPCKAIVQGDSLIPEISAASILAKVLRDEEMVALDKIYPGYGFAEHKGYATPVHKEALMRLGPCKIHRRSYSPVADLISK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADE_FLOCH
Sequence: MATSRDFGREPPRQQQDSDEAGHTLHDGCQHVSEHPQIDVTAHDSSASALPGDETTVGAATAALDPKEEERDPNIVDWDGPDDPANPQNWPPLKKWGNVAVLSIITFMVPLASSMFAPGIPQVLSDFDTNNPSLATFVVSVYILGLAAGPLVLAPMSELYGRVVIYHVGNVLFIIFTVACALSTNMNMLIAFRFLCGLVGAGPIAIGGGTIADLTTLQQRGTAMSVWSLGPLLGPSVGPVAGGFLSQAEGWRWIFWVLAITAGVITIAGLLVLRETHPGTLLERKTRRLRKETGNMNLRSKLDLQVAPRTLFLRSIVRPSKLLVLSPICLVLSVYSAFVYAMIYFMISTFTFVFQDNYGFSEGIVGLVYIALGLGMLFGVVVQQAIGNRIMKRLADKLNKGKPKPEYRIPPTLLAGFLIPTGLFIYGWTVQYHIQWAVPLLGALLAGMGICIINISTNLYLVDAFTLYAASALAASTVLRSIFGATFPLFALQMYETLGLGWGNSLLAFIAVAMFAIPPLLFYYGERLRSHPRFQVKL
What is the function of this protein?
Efflux pump that might be required for efficient secretion of radicicol or other secondary metabolies produced by the radicicol gene cluster (PubMed:19101477).
What are the official names of this protein?
Efflux pump radE, Radicicol biosynthesis cluster protein radE.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPAT8_ARATH
Sequence: MSPEKKSQNFPPITECRDGEYDSIAADLDGTLLLSRSSFPYFMLVAVEAGSLLRGLILLLSLPFVIISYLFVSESLGIQILIFISFAGLKIRDIELVSRAVLPRFYAADVRKDSFEVFDKCKRKVVVTANPIVMVEAFVKDYLGGDKVLGTEIEVNPKTNRATGFVKKPGVLVGDLKRLAILKEFGNESPDLGLGDRTSDHDFMSLCKKGYMVHATKSATTIPKERLKNRIVFHDGRLAQRPTPLNAIITYLWLPFGFILSIIRVYFNLPLPERFVRYTYEMLGIHLTIRGHRPPPPSPGTLGNLYVLNHRTALDPIIVAIALGRKICCVTYSVSRLSLMLSPIPAVALTRDRATDAANMRKLLEKGDLVICPEGTTCREEYLLRFSALFAELSDRIVPVAMNCKQGMFNGTTVRGVKFWDPYFFFMNPRPSYEATFLDRLPEEMTVNGGGKTPIEVANYVQKVIGAVLGFECTELTRKDKYLLLGGNDGKVESINNTKK
What is the function of this protein?
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
What are the official names of this protein?
Probable glycerol-3-phosphate acyltransferase 8.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BIOB_FRATF
Sequence: MTLQQIKEIYLRPLTELILKALEIHNKNFGNDIELCSLKSIKTGTCPEDCKYCPQSGHYNTSIEKHKLLDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKDFDQVAEIITEVKNLGLETCVTLGSINADEATKLKQAGLDYYNHNLDTSREFYPEIITTRKFEERIETIRNVANANINVCCGGILGMGESLDDRFNLLLELLQLPAAPKSIPINTLIPVKGTPLGDKYTNAQIDSFELVRFIATTRILFPQARLRLSAGRENMSLETQTLCFLAGINSIFYGNKLLTENNATVNSDNFLLAKLGLKSNAELC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CD3E_PIG
Sequence: MPSGNLWKVLGLCLLSVGAWGQEDIERPDEDTQKTFKVSISGDKVELTCPEDPESEKMTWKRNDMQIYESYDNYMLLESFSEVENSGYYTCTVGEKTSHRLYLKARVCENCVEVDLMAVVTIIVVDICITLGLLMVVYYYSKSRKAKAMPVTRGAGAGGRPRGQNRERPPPVPNPDYEPIRKGQRDLYSGLNQRGR
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.  In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development.  Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E.  Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region.
What are the official names of this protein?
T-cell surface glycoprotein CD3 epsilon chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL6_RHOE4
Sequence: MSRIGKIPVTVPAGVDVTISGQDVTVKGPKGTLALTISEPIAIEKAEDGSLSVTRPDDERRSRALHGLSRTLVANIITGVTEGYTKKMEIHGVGYRVALKGKDLEFALGFSHPVPIEAPEGITFVVESPTRFSVSGIDKQKVGQISANIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CYB_LAEWI
Sequence: MTNIRKSHPLIKIVNNSFIDLPAPSSISSWWNFGSLLGICLALQILTGLFLAMHYTSDTSTAFNSVAHICRDVNYGWMLRYLHANGASMFFICLYLHVGRGLYYGSYMFKETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDILGLFMMIWALLSLVLFMPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALALSILILIIIPLLHTSKQRSMIFRPLSQCSFWLLTADLLTLTWIGGQPVEHPYIIIGQLASILYFLIIIVIMPLAXLMENLLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPIS_BARQU
Sequence: MSPNIRPFIAGNWKMNGTVESLGELRAIAAGVSSDLGHLFEALICVPATLLSRASDALSGENLLLGGQNCHFDDCGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVCAKVQAAWRAGLVALICVGETLEERTSNKVFNVLTRQLEGSLPDGATAENVIIAYEPVWAIGTGNSPTSAVVAEVHDFIRHKMCSRFGDDGRKMRLLYGGSVKPSNAFELLSTVHVNGALIGGASLKAIDFLTICDVYRKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1319_SYNY3
Sequence: MRILSNVNLMGLLIVLLAAIFFCFHNVIVRILYSQQNILGIWQVGGFVTPTLSHSFLLLLLRMLWVVPLMALISQRLYGNTWREINQLKQPVNRPVIWEAMGCGFLMFLYLVLLYISISFIPTGIAITLFFTYPIFTALLAWRLFNDVPSLLRWLVIGLTLIGTFLTIPYAYGGEQQTLVLGVSTGIASGIVYAGYTVFAQRSFQRLHPVPFTWISFATTLILSILCLIIWQPHEGNLPWLAITIGSLLSALFTLAGHVLNNWGIHLIGASRAAIIGATNPALTVVLAGLAIQESLTNIQIFGVCLVTFSIALLNYEKVSPSTGKNSLK
What are the official names of this protein?
Uncharacterized transporter sll1319.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIC60_ARTBC
Sequence: MLRNSIAPSRGLGSLARQRLTTSGRNLITKRSYVKGKSAAWPPGRSIASVLPARKTSCATFTTSATRGNEQNIRSPPSPSSASAISPEGISKPASSSPAGQTSPGSSVNSPEPPKAQTSAPPPPPPPPPPAPKAKGRFGRSLLYLVLTAGVAYAGGVWFSLRSDNFHDFFTEYVPYGEEAVLYFEELDFRRRFPNATRHINTRPAAPRDEGEKVTIPSKSGVSWKVAENEGTSDVTHKGRHMSAVDAEVPRTGGDAKSAPNKPTTEDKKDSEKTGSKKDESKERVPVTDTKKSTVSLDEPRKPAVATVASIEPLASLQDDPIIQELTKIVNGLIAVINADESASKLAAPIAKAKDDFLKLGEQISSIKKEAHAAAQEEIKNAHKEFERSATELVRRIDEVRSEEAAEYREEFETEREKLANSYQEKIKTEVERANAVAEQRLRNELVEQAIELNRKFLSDVDTLVEKERQGRFSKLSELSAQVAELEKLTAGWNEVIGANLTTQQLQVAVDAVHSALESESMPRPFINELLAVKSLAGQDPIVNAAISSINPTAYQRGIPSTAQIIDRFRRVANEVRKASLLPEDAGVASHATSYLMSKVMFKKEASSSGDDVESILTRTEKLLEQGNLDDAAREMNALRGWSKLLSKDWLADVRRVLEVRQALEVCFLSLLPTLSLLIYYNEC
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: QUEC_DECAR
Sequence: MMKKAVVLLSGGLDSATCLAIARSQGFESYCLSFNYGQRHCAELVAADRVVKALGAAEHRVLNFGLAQFGGSALTDTNIAVPTEGVQPGIPVTYVPARNTIMLSLALAWAEVLGSRDIFVGVNAVDYSGYPDCRPEYIAAFETMANLATKAGVEGHKLSIHAPLIDLSKAEIIRTGAALGVDYSLTVSCYQADEQGRACGVCDSCRLRAEGFAAAGLADPTLYRA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ACCA_BURM9
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLTPWQVSQIARHPQRPYTLDYVSELFTDFHELHGDRAFADDQSIVGGLARFNGHACMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRVAEKFGLPIFTFVDTPGAYPGVGAEERGQSEAIGHNLYVMAELKTPIIATVIGEGGSGGALAIAVADTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIVNEPLGGAHRDPKGMAALLRRALGDSLRQFQGMSVDALRERRFERLMAYGKFKETTPRA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_CARRE
Sequence: IATVDCSDYPKPVCTLEDMPLCGSDNITYHNKCYFCNAVAHSNGTLTFSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_BACCQ
Sequence: MSSVPASAYLTLAIILFCIGLFGALTKRNTVIVLVCIELMLNAANLNLVAFSKLGLFPNVTGQIFSLFTMAVAAAEAAVGLAILIALYRNRTTVHVDEMDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPI_DIALT
Sequence: ALIFATLSAAYIGEALE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FLAJ_METJA
Sequence: MVIVVFDLLPRVGLKPRDYLLRIVLPALITSIVLILLGFMLFSGIILYIYLLLPIIILVSAIGYPYIALDSQKNKINERLHIFITKFGTLSITDLNRKDLLKILSEEREELGELAKESEKLYVLTDKWGRSLAEACRFLAQRTPSSEFADFLDRLAYALDSGEELKEFLIKEQDIVMDDYAAFYKRMLYSLDMYKELYVSAMTSIAFFLAFSILVPFLLPYNFVFMATIALFAFFAVELLIVVVIRNRLPFDRLWHTGEKPTETDIKLRKWLIISVILVVILLPFLLWAKYIVGLSPFSQMPYMILVALGFTPLAIGGFVALKEEEKVKRKEFVFPDFLRSLGDSVSAKGGGMVSSLEYLSNHDFGPLTHDIKRLYKRLALGIDSNKSWRLFGFDSCSYLIQLFSDIFSRCIYFGGDPKTAAEIISKNFRKIVQLRKSKYQNIQQFVGVVYGLGGGLALALFASLGVAKMINDLYSSLSIPETVIHILNIAPISNVDVVEYIIFGSLIVYSIISAILIKIMDGGHKFVSLLHFVAILWICAIVAYITKLIVSQVLGVSVPLY
What are the official names of this protein?
Flagella accessory protein J.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1286.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Archaeal flagellum.
Protein: IGFL1_HUMAN
Sequence: MAPRGCIVAVFAIFCISRLLCSHGAPVAPMTPYLMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCGNCTFRVCFEQCCPWTFMVKLINQNCDSARTSDDRLCRSVS
What is the function of this protein?
Probable ligand of the IGFLR1 cell membrane receptor.
What are the official names of this protein?
Insulin growth factor-like family member 1.
What is the protein family that this protein belongs to?
Belongs to the IGFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSRP_VIBCM
Sequence: MQMESQRRDVFYVSDGTAITCETLGHVVLGQFAVQPNEKTFPFVESDEKLSELLKQIQRSYQLHGVKPLVFFSMVIPEMRTRLLQAPAHFYDVLESIVQRVSLDIEMEPAPKLQRSRSVGKDSDTYFDRIAAIEYTLAHDDGVSLKDLDRADIILLGVSRSGKTPTSLYMAMQFGLRVVNYPFIAEDMHAMRLLPEFEFHRHKLFGLTINAERLTEIRENRLAGSEYASNQQCQQELATVEALFRREAISYINTSSLSVEEISTRILERTGLKRRLF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.