PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_ACIC5
Sequence: MAKTYYDHDADLALIQQKKVAIIGYGSQGHAHALGLKDSGVEVRVGLAPNSRSIEKAKKAGLETGTVAEVAAWADVIMILAPDTAQAAIYEESIAPHLKAGKTLMFAHGFNIRYDAIQPPKDVDVSLVAPKAPGHRVREVFVEGGGTPGLVAVHQDASGQALALALAYAKAIGCTRAGVLETTFKEETETDLFGEQAVLCGGTAALVKAGFETLVNAGYQPEVAYFECLHELKLIVDLMYRGGLAYMRYSISDTAEWGDYVAGPRIVTDETRAAMKKLLTDIQDGTFAKRWIEENKTGRKELDAIRAQEAKHPIETVGEKLRAAMPFLDPVTVKDGYPQPAGAKPKEA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SR542_ARATH
Sequence: MVLAELGGRIMSAIQKMNNVTIIDEKALNDCLNEITRALLQSDVSFPLVKEMQTNIKKIVNLEDLAAGHNKRRIIEQAIFSELCKMLDPGKSAFAPKKAKPSVVMFVGLQGEVLEKPQLVPSMLIIIRRKGYKPALVCADTFRAGAFDQLKQNATKSKIPYYGSYTGSDPVKIAVEGVDRFKKENCDLIIVDTSGRHKQQASLFEEMRQISEATKPDLVIFVMDSSIGQTAFEQARAFKQTVAVGAVIITKMDGHAKGGGTLSAVAATKSPVIFIGTGEHMDEFEVFDAKPFVSRLLGNGDMSGFVNKLQEVVPKDQQPELLEMLSHGKFTLRIMYDQFQNMLNMGPLKEVFSMLPGMRAEMMPEGHEKESQAKIKRYMTMMDSMTNEELDSSNPKVFNESRIMRIARGSGRIVREVMEMLEEYKRLTTMWGKVKGLKNLEKGNMSALSKNKNSQQLSKVLPAQMLKQIGGMSGLQSLMKQMGSGKDLMGMFGGRDE
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane.  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA.  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA.  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54 2, Signal recognition particle 54 kDa protein 2, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL15_ARATH
Sequence: MVVMSRVSFYSSFLLLLLEVVVASSEFDDEGRTSFSPTTAIIMIVLVSVFFALGCISVYMRRCLQHALGMDSGGGPGNWLNVRQTTEPGLDASVIETFPTFPYSTVKTLRIGKEALECPVCLNEFEDDETLRLIPQCCHVFHPGCIDAWLRSQTTCPLCRANLVPVPGESVSSEIPGLARETGQNSLRTPIDDNRKRVLTSPDERLIDSVAWTGNQSMPRKSMSTGWKLAELYSPASSPGQPEENLDRYTLRLPQEIHDQLVNSSLGKQGSKGQLALPQERSSVRGFRTGSLGTEKNYFYFERFDQDGRLDRRPFSITPPYHTRSIQSPDEIINASGNYQDRAGAPKGLLLAIRSPFDRLFTGKKNAGERSYLQSGDASPV
What is the function of this protein?
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8, UBC10, UBC11, UBC28 and UBC29 in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase ATL15, RING-H2 finger protein ATL15, RING-type E3 ubiquitin transferase ATL15.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FTSL_FRATT
Sequence: MMLTNRQIRVRLFESLKNSFFKKTVGISFALLFILLITAFSLIVVRFEYKLQLNEQKNLILEDTRLDEQWSQIVLEYSSLATPTAVEKFAQKEKMTLPTRKTIGFLNEQKEELNNE
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: METK_RALPJ
Sequence: MSNDFLFTSESVSEGHPDKVADQISDAILDAILAQDKYARVAAETLCNTGLVVLAGEITTTANVDYIHVARETIKRIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRASDDYLNQGAGDQGLMFGYACDETPELMPFPIYYAHRLVERQSQLRRDGRLPWLRPDAKSQVTVRYVDGKPHSVDTVVLSTQHAPEMSQEAIREAVIEEIIKPVLPSHMLAETKYLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQVQVSYAIGVARPINITVYTEGTGVIPDEQIAKLVQEHFDLRPKGIVQMLDLLRPVYEKTAAYGHFGREEPEFSWEATDKVLLLREAAGLAGEPAKAFA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_AERPE
Sequence: MAKTLDSPGVLVVDFGGQYAHLIARRIRELGVYSEIVPATSLDALGEALPRAAGVVLSGGPGSVWGSRHDEAAAMVLQLGKPVLGICYGHQLLAKVLGGEVGRSPLPEFGPTEVEVLDYGILLNGLPSRFKVWMSHYDAVLRPPGEAKVLARTPGSPVAAMELWGRVFGVQWHPEVRHTQYGREVLDNWLSLVGAPRTWRPGDMVSELVESVKKEVGDALAVAAVSGGVDSTVAALIAKKAIGSRLYPVFIDHGLHPEGEVERVVKLLSRLGLEPVMVDAGEEFLAALEGVGDPEEKRRVVGRVYAEVLERAARDIGAEYLVQGTIYPDVIESGARPGADTIKTHHNVGGLPKDMRLKLVEPLRYFYKDEVRLLAEKLGVPRELIWKQPVPGPGLAVRVEGPITREKLRIVRRADAIVREEVEAAGLGGKLWQYFAVLTASMATGVRGDSRSYGYVVAVRAVESVDAMTAKPAELPWWLLERIARRITSEIPEVVRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: THIO_CALJA
Sequence: MVKQIDSKDAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVVFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINEFV
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).  Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.  Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.  Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA). Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. Secreted by a leaderless secretory pathway.
Protein: RL16_MICLC
Sequence: MLIPRRVKHRKQHHPKRSGAAKGGTTVTFGEWGIQALTPAYVTNRQIEAARIAMTRYIKRGGKVWINIYPDRPITKKPAETRMGSGKGSPEWWVANVKPGRVLFELSGVTEDVAREALRLAIHKLPLKARIIRREGGE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y515_LACLM
Sequence: MKENYNYPLDLSWSTTEMTEVLSFFNQVEKFYESKVEKELFLESYAAFKKVVPSKMQEKQLGRDFEQSSGYSLYRALKEVEASGKRFVSADKA
What are the official names of this protein?
UPF0223 protein llmg_0515.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: ZN668_MACFA
Sequence: MEVEAAEARSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGDKVAGSAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKPYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGAPPAQELVVGLALPVGVAGEGSATPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEVGGEEADEKPPQFVCRECKETSSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPVPMGTPTPLEPLAALLGIPEEGPA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 668.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UVRB_CLOBJ
Sequence: MNQFKVISKFNPTGDQPKAIKSIAKGIEKREKFQTLIGVTGSGKTFTMANIIEKVQKPTLVLAHNKTLAAQLCSEFREFFPNNAVEYFVSYYDYYQPEAYVAQSDTYIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGNPEEYKKLTISLREGMEKDRDEIIKKLVEIQYERNDIDFSRGTFRVKGDVLDIFPASSSSKAVRVEFFGDEIDRIKEFDVLTGETITKLKHISIFPASHFATSKDRLEVAIKDIEEELEERVKELVSQDKILEAQRLKQRTNFDIEMMREVGYCTGIENYSRVLDGRAKGTPPQTLLDYFPQDFLLFIDESHVTLPQVKAMQAGDKSRKDSLVEYGFRLPCAYDNRPLTFKEFENKLNQVVFVSATPAKYELEYSTNTAEQVIRPTGLLDPEIIVKPVKGQIDDLYTSIQETIKRGFRILVTTLTKKMAEDLTDYLKEMGVKTRYLHSDIDTIERMKIIHDLRKGEFHVLVGINLLREGLDIPEVALVTILDADKEGFLRSETSLIQTVGRAARNSESKVIMYGDVITKSMEKTIKETNRRRKIQMEYNEEYGIVPKTIIKDIREVIQISDIAEERKEYDNLNEALKSYNNDIDKLIEKYEEEMKEAAQNLQFEKAAHLRDVIYKLKKDKETEL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRX43_CAEEL
Sequence: MVLRNLTAMAIYDQTFVYSSDDALAGMVVSMECLTGLFLLVAVIIGCFRIAALKSPFGILMINQNCAQLMACINSGSFSTLGVLLNIKPVLSISYLFGNFSIFLLPVILISFLLMSFNRFCACFFPLRYQNLFSSSMIRTFIVFNWLLSLVAGSYLVVVRECNFVFYHFGWLFAGSVSVKCGTLLSLYSISIQTVLSITIVGLDVVTLVALMAFRSKVYQSHSVEVRRRELSFSGQVIIQGAVFLCHGAWYDMGHAILPGNDDRWKFFFTTSFSSNLLHVFDPVVVFAFNKEFRRWLFRNFNVPTAQKRIVTVVSAHNT
What is the function of this protein?
Receptor for the ascaroside pheromone icas#9 which suppresses exploratory forgaging behavior.  In response to ascaroside icas#9, may furthermore play a role in the expression of genes in the TGF-beta signaling pathway, such as daf-7, and in insulin signaling pathway, such as daf-28, which may in turn contribute to exploratory behavior.
What are the official names of this protein?
Serpentine receptor class X-43, Protein srx-43.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, cilium.
Protein: RS19_SHIFL
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HOA1_MYCSK
Sequence: MSTKDIFFNPIWDVRMTDTSLRDGSHHKRHQFTKDEVGAIVAALDTAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAETAKEAKIAFLMLPGVGTKEDIKEAQNNGGSICRIATHCTEADVSIQHFGLARELGLETVGFLMMSHTIPPEKLAQQARIMADAGCQCVYVVDSAGALVLEGVRDRVAALVAELGDDAQVGFHGHENLGLGVANSVEAVRAGAKQIDGSCRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQSERYGVPAHQLLHRAGQRKLIGGQEDQLIDIALEIKREQDSGATAAH
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: ALF_SCHPO
Sequence: MGILDIVPTGVITGDNVLKLFTYAREHGFAIPAINVTSSSTAIAALEAAREARSPIILQTSNGGAHFFAGKESSNEGQKASIAGSIAAAHYIRSIAPFFGVPVVMHSDHCAKKLLPWMDGMFEADEAYFKIHGEPLFSSHMLDLSEEPKKENIAQVKEYCKRAVPMKIWIEMEIGITGGEEDGVDNSHVSHTELYTQPEDIWDVYRELSSVTPYFSIAAAFGNVHGVYKPGNVKLQPALLGQHQAYVKEQLKTTNDKPVFFVFHGGSGSSVNEFRTGIKCGVVKVNIDTDTQFAYVEGVRDYVLKYKDYLMTPVGNPEGADKPNKKKFDPRVWIHEGEKTMTKRVLTALEDFYTVNTL
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: DOF45_ARATH
Sequence: MDNLNVFANEDNQVNDVKPPPPPPRVCARCDSDNTKFCYYNNYCEFQPRYFCKNCRRYWTHGGALRNIPIGGSSRAKRARVNQPSVARMVSVETQRGNNQPFSNVQENVHLVGSFGASSSSSVGAVGNLFGSLYDIHGGMVTNLHPTRTVRPNHRLAFHDGSFEQDYYDVGSDNLLVNQQVGGYGYHMNPVDQFKWNQSFNNTMNMNYNNDSTSGSSRGSDMNVNHDNKKIRYRNSVIMHPCHLEKDGP
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
What are the official names of this protein?
Dof zinc finger protein DOF4.5, AtDOF4.5.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURD_RICPR
Sequence: MNAYKKQKIGIFGLGKTGISVYEELKNKYDLIVYDDLEANRDIFKELFGNNLITVLSDSRWQDLDKIVLSPGVPLTHEVVRIAHHFNIPIISDIDLFFEKSKNLKFIAITGTNGKSTTTALISHILNSNGLDYPVAGNIGVPALQAKASNEGYVLELSSFQLDLVKSFTVKVAVLLNITPDHLDRYQDMNDYIAAKAKIFDRMDKDSYAVINIDNDYCRKIFVLLQKDQSIKLIPFSVTKILKNGISIVDDKIHDNDLTYKLPLNKNLQGLHNCENIAASYAVAKIIGLESKKILESISSFQSLHHRMQYIGSINNISFYNDSKATNAISALQSIKALDNIYWLAGGIPKEGGIEGIKPYFNKIKKAYFYGQAKAMFANTAKNIIDFVICDNLEYAFNIAYKDAVSDTTEVKNILLAPSCSSYDQFKNFEERGELFIKLSKRHWQ
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2270_BACAH
Sequence: MLGIHVKKTKEELIISWQLAKITIPLRDVIEVTEDATYAGVEDTSAIRIGTAYGTTDRILIKTVKQNYVLFTTNKVSILNAINA
What are the official names of this protein?
UPF0457 protein BALH_2270.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: VSR_BSMV
Sequence: MMATFSCVCCGTSTTSTYCGKRCERKHVYSETRNKRLELYKKYLLEPQKCALNGIVGHSCGMPCSIAEEACDQLPIVSRFCGQKHADLYDSLLKRSEQELLLEFLQKKMQELKLSHIVKMAKLESEVNAIRKSVASSFEDSVGCDDSSSVSKL
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (PubMed:12438624).  Promotes viral cell-to-cell long distance movement by enhancing the ATPase activity of TGB1 (PubMed:12438624, PubMed:32730331).  Enhances RNA helicase activity of replication protein alpha-A (PubMed:28388677).  Suppresses autophagy induced by the host as a defense mechanism against viral infection (PubMed:29848767).
What are the official names of this protein?
Suppressor of RNA silencing, Gamma-B protein, Gammab protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae suppressor of RNA silencing family.
What are the subcellular locations of this protein?
Host chloroplast envelope. Host endoplasmic reticulum. Host cell junction, host plasmodesma. Note=Recruited by the replication protein alpha-A to viral replication sites at the host chloroplast membrane.
Protein: MSRB_SALHS
Sequence: MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: GATC_CHLTR
Sequence: MTESYVNKEEIISLAKNAALELEDAHVEEFVTSMNDVIALMQEVIAIDISDIILEATVHHFVGPEDLREDMVTSDFTQEEFLSNVPVSLGGLVKVPTVIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MTGA_NITMU
Sequence: MFFKRWFWRIFLFFIAVIFVYQFWIFSQIVYWNYFNPSSSAFMQTRLETLREKNTKAALRTRWIPYEQISPHLKRAIIAAEDAKFLEHEGFDFDAIQKAYEKNLKKGRLIMGGSTISQQLAKNLFLSGDKTPWRKLQEAFITLMLEKVMSKRRILEIYLNVIEWGNVVFGAEAAARHYYGISASSVSREQAARLAAMVPSPRFYDENRNTPWLSKKTRMILGRMASASIP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SSN3_YEAST
Sequence: MYNGKDRAQNSYQPMYQRPMQVQGQQQAQSFVGKKNTIGSVHGKAPMLMANNDVFTIGPYRARKDRMRVSVLEKYEVIGYIAAGTYGKVYKAKRQINSGTNSANGSSLNGTNAKIPQFDSTQPKSSSSMDMQANTNALRRNLLKDEGVTPGRIRTTREDVSPHYNSQKQTLIKKPLTVFYAIKKFKTEKDGVEQLHYTGISQSACREMALCRELHNKHLTTLVEIFLERKCVHMVYEYAEHDLLQIIHFHSHPEKRMIPPRMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMVTIDGCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWSVGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYDQITKFPKYRDNLATWYHSAGGRDKHALSLLYHLLNYDPIKRIDAFNALEHKYFTESDIPVSENVFEGLTYKYPARRIHTNDNDIMNLGSRTKNNTQASGITAGAAANALGGLGVNRRILAAAAAAAAAVSGNNASDEPSRKKNRR
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.  The SSN3/SRB10 and SSN8/SRB11 kinase-cyclin pair may also positively and negatively regulate numerous transcriptional activators in response to changes in nutritional and physiological conditions.  Phosphorylates GCN4, promoting its ubiquitin-mediated degradation, and MSN2, promoting its nuclear exclusion.  Phosphorylates STE12, thereby promoting its degradation and inhibition of filamentous growth.  Phosphorylates GAL4, and this phosphorylation is required for efficient galactose-inducible transcription.  Also phosphorylates BDF1 and the TAF2 subunit of the TFIID complex.
What are the official names of this protein?
Meiotic mRNA stability protein kinase SSN3, Cyclin-dependent kinase 8, Suppressor of RNA polymerase B SRB10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPRN_CHICK
Sequence: MRQRVACCWVLLLLAATFCQPAAAKGGRGGSRGAARGMARGAARSRHRGLPRYGGALRVAAAAAAAGAAAGAALHQARAETEYHEGNGTAWTSVAPGWVEWGWAMPWLCPLAAILHH
What is the function of this protein?
Prion-like protein that has PrP(C)-like neuroprotective activity.
What are the official names of this protein?
Shadow of prion protein, Protein shadoo.
What is the protein family that this protein belongs to?
Belongs to the SPRN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PDRP_CHESB
Sequence: MHKPQSFFHLHLISDATGETLLAAGRAAAAQYKNARAIEHIYPLVRTEKQLEKVFASIDEEPGIVLYTIVDQKLARQVDERCQAMGLPCVSVLEPVLAVFQSYLGTPAGRRVGAQHVLDAEYFRRIDALNFTMEHDDGQLPHNVEEADIVLVGVSRTSKTPTSIYLANRGIKTANVPIVLDAPLPEPLLNAKRPLVVGLIASAERISQVRQNRLLGASHVDFDAYVDRAEIARELAYARQLCNRHNWPVIDVTRRSIEETAAAILALRGKSW
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: DOC2A_RAT
Sequence: MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRRGPGPEGGGGGRGFGEAPAHLAPLALAPPAALLGATTPDDGAEVDSYDSDDTTALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEMELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWRDCLHQPDTAVERWHTLTSELPPAAGALPLA
What is the function of this protein?
Calcium sensor which most probably regulates fusion of vesicles with membranes.  Binds calcium and phospholipids.  May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A.  May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells.  Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells (By similarity).
What are the official names of this protein?
Double C2-like domain-containing protein alpha, Doc2-alpha.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Synapse, synaptosome. Lysosome.