PharMolix/UniProtQA huggingface dataset:
Protein: TMTC1_DROME
Sequence: MHTPKCRRPSMSATLSHKDLAGLAGCSALAFVLYLNTLNAGFVYDDRRAILANGDVTGARPLANLLRNDFWGTPLVDSGSHGSWRPLCVLSFRLNYLAGGMTPLGYHLVNVMLHCVATWLVFLVARTLLPSRMGVLAAGALFAVHPAHTEAVAGLVGRADLASCVCYLLAYLSYRRHMLNREWGSLILTIMLALAALLCKETAITALLLCGLCDVLSPVGRENSDKVCDGSISGLASFNFQRRFRSLSILGFTLLCGLYCRLSLLPRPSTAFSAADNPTAHESCFWTRTLTFLYLPVANFGILLWPQELSFDWGMEAVSRIRTLWDARNILTAGFYGSLVAILWKGSGLRSAASPMDFAEVANISLPLLRRLGGNSCHTWLGLTCDCHHQLSAPSYRSASAIYSTSSKSKSASWTAAPILGTAFLVLPFLPASNLLFYVGFVMAERVLYLPSVGYCLLFGLGFGHLWQRVNSSWRSRLMLLCGLALLLGVHGVRTFRRNLDWRDEEQLFRSAISINPPKALGNLGSVLSAQGRYEEAELTLRMTLGHRPTMADAHFNLGVVHQKQLNFSSAIPCFRRAIELRPQLAVAYLNLGTSLISLGDHRQEAISVLRTGARLEGSGVRDRGAHVEARYTCYLQLSVLYRSDGRLQDAAAALRESLKALPLLPQKQRAVLHLRLGEILAELQDWNEAEHQQRLAMQLQPEQGAAYVTYGQTLARNGSRLAEAESWFKRALQLAPLEPSSHHHYADFLEQQERHHEALGLRLRAAALAPQDYTLQSCVADALRLLNRLAEAELWYRKAVTLQPMAAHAHANLGAILQMRGLRKEAVACYHKALELQPGHAISRANLARMNVHKHENE
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
What are the official names of this protein?
Protein O-mannosyl-transferase TMTC1, Transmembrane and TPR repeat-containing protein CG31690.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: TORD_SHIDS
Sequence: MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVNELENCVATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCHQYDSFGFYAALSQLLLVLVEGDHQNR
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC6_YEAST
Sequence: MSAIPITPTKRIRRNLFDDAPATPPRPLKRKKLQFTDVTPESSPEKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPDGRLESVAVTSINCISLGEPSSIFQKIFDSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLPTIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGSLNSAQVPLTPTTSPVKKSYPEPQGKIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLILCTIIQSLKLNSDATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKKTKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFLH
What is the function of this protein?
Plays a crucial role in forming the pre-replicative complexes.  Interacts with the origin recognition complex (ORC) and MCM2-7 helicase complex leading to the linking of those complexes and loading of the replicative helicase MCM2-7 onto the pre-replicative complexes.  Required for the initiation of DNA replication and then actively participates in the suppression of nuclear division.
What are the official names of this protein?
Cell division control protein 6.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FFSC4_GIBF5
Sequence: MVPSLITPPPSRSGEATPQKDACLNPVNIAEPEGHWIKLPEALFSSIMAVEPEVNPLYRTSKALSDEWLKTALRMNDKTAVIWSRLDIAYMSAICAPHADLETLKLMNDWNGWVFAFDDPFDEGTFANDPIKAAEEVIYTLATLDNIHPVVSPDENPLRHTLQSCWMRFRERSSPSLQYRWKKHLTMYCVGVLQQVGVQHRATRPTIEEYMDMRAGCVGAYPCIGLMEFAEGIDIPQNVMDHPSMQAISRITCDLVTLQNDLCSYRKDLIQGEESNIIFILKDQGMTDQQAVDQIGEMLYDCYRRWHMALANLPFWGEGIDRDVIKFVTGCRNIALGNLHWSLYTFRYLGNDGPEVKRTRMMKLP
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene koraiol.
What are the official names of this protein?
Terpene cyclase 4, Sesquiterpene synthase 4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: GBB3_HUMAN
Sequence: MGEMEQLRQEAEQLKKQIADARKACADVTLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Transducin beta chain 3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: PUR8_ECOL6
Sequence: MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELK
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: RUVB_SYNFM
Sequence: MTERIVEPKPHEDDLPVENSLRPRRLDEYVGQQTVKENLAVFIEAARQRAEPLDHVLFHGFPGLGKTSLATVISNELGVNMRSTSGPVIERAGDLAAILTNLEQGDVLFIDEIHRLNHVVEEILYPAMEDFQLDIIIGQGPSARTIKLDLPPFTLVGATTRAGLLSPPLRDRFGVTLRLEFYKVDELKLIVTRSARILGIRVDAEGALEIAKRSRGTPRIANRLLRRVRDYAEVRADGRITREVADLALRMLDVDEKGFDGMDRKILSTIIEKYDGGPVGIETLSAAVSEERDTLEDVYEPYLIQEGFLNKTPRGRLATRLAYEHLGISVRSCRQLKIY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PQIC_SHIFL
Sequence: MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNRLLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGWVVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDGYDEMVKVLAGVWSQEAASIAQEIKRLP
What is the function of this protein?
Component of a transport pathway that contributes to membrane integrity.
What are the official names of this protein?
Intermembrane transport lipoprotein PqiC.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: RS17_BIFAA
Sequence: MAEERNFRKVRRGYVVSDKMDKTISVELEQRSTHPLYGKVVRSTRTVKVHDEHNEAHIGDLVSIMETRPLSKTKRWRLDSIIERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: P53_XIPMA
Sequence: MEEADLTLPLSQDTFHDLWNNVFLSTENESLPPPEGLLSQNMDFWEDPETMQETKNVPTAPTVPAISNYAGEHGFNLEFNDSGTAKSVTSTYSVKLGKLFCQLAKTTPIGVLVKEEPPQGAVIRATAVYKKTEHVGEVVKRCPHHQSEDLSDNKSHLIRVEGSQLAQYFEDPNTRRHSVTVPYERPQLGSEMTTILLSFMCNSSCMGGMNRRPILTILTLETTEGEVLGRRCFEVRVCACPGRDRKTEEGNLEKSGTKQTKKRKSAPAPDTSTAKKSKSASSGEDEDKEIYTLSIRGRNRYLWFKSLNDGLELMDKTGPKIKQEIPAPSSGKRLLKGGSDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity).
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y797_STRP3
Sequence: MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFINDMPEGTYYPQGEMKQKS
What are the official names of this protein?
Probable tautomerase SpyM3_0797.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: RSMA_RHOPA
Sequence: MSAIDDLPPLREVIRRHDLAARKSLGQNFLLDLNLTARIARAAGPLEGVTVVEIGPGPGGLTRALLATGAKRVIAIERDERALGALEEIAAHYPGRLDIISGDAMEFDPRPLLNGDRARIVANLPYNIATPLLIGWLCAEPWPPWYEMMVLMFQREVAQRIVAHHDDDAYGRLAVLANWRAETQMLFDISPSAFVPPPKVTSSVVRLVPRAQPEPCDRAALEQVAAAAFGQRRKMLRQSLKSLGVDPAQLTAAAGIDPARRAETVPVSGFVAMANELANSRAIRTQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_HIRBI
Sequence: MDILNDISIAAPEALLIGVALIGVLLGATFKQSFNGLSRLLGALALAGAAFLAASQSAVDASTAFNGLYKVTPFIAIAKAVSYGVGAIALLVAGGYLHRENMNKFEYTLLVMFGSAGMGVMLSANNLMTLYMGIETLSLSSYVLAAFNRDSRRSAEAGLKYFVLGALASGLLLFGCSLVYGYTGFASFEQIAAADQSIGLTFGLVLILMALSFKASAAPFHVWTPDVYEGAPTPVVTFFSTAPKLATVAVLANIMFTVFGVYEESWMLIIAIVSAISMLVGAFGGLAQNNIKRLLAYSSIANVGYALMGVAAGEVNGAASVLTYMTIYVITTLGMFGIVLAMRRRDGQVEEISDLNGLSTSRPGLAVAMTVLVFSVAGIPPMAGFLGKWVVFEAALKSELYWLVAVGVIGSVVSLGYYLRLIWAMWAKTSDEEALEPADGMVSVSIYGATILAFPVLVIWIGWMTGIIGTAAAAG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YFPC_SCHPO
Sequence: MDGNRRVRFNTDRRPYLSPLQTSFPSSTSFQTPTFLIEEDDEDTEDDDGPQVLPVHRAPSPAAFRKRGSITSMDQYLVNMPAVPSPTASKVGLLDARNTDVESYAASYKTQSSSNSVNSLPMRRPTLDRSYSAPMIAAKNLQSDPEKMSNVESTNELPSTTTEAYKLVAAHTAARLEHMRLNALKAANDEGEDVKDNEQDDNIDESDPFANPKASYRGGVLSNLLKLYTNSNTVTSSRISLKHTDPTKWQKHAKRTASSNSLTDLLHASNQTFMAPASGLQSTEEIPQFSKTGHSRGRKFNFHHHSRKNSGLNEEYKITIHLADILQRQKYILKLCRALMVYGAPSHRLEEHMASAAKVLEIEGQFLYIPGCMIVSFGDVNTHTSDMHIVRVNQTIDLGRLKLVHDIYKAVLHDRMGVEEAIRGLDEIFKSPPYFRTWILVVFYGFASATILPMSFQGGWIDLPIAFILGCLVGILQHYIAPRSTMYNSLFEVTGSIITSFLSRAFGSIRYSGGRRFCFSALAEGAIVLILPGYIVLCGSLELQSKNIVAGGVRMFYAIIYSLFLSFGISIGAALYGWMDHNATDSTSCPVSTQMDDKWKILFVPLFTLCLLIVNQARPSQWPVSIFISCAGYVVNYFTAKHFGSNPIANAIGSFAIGCLGNIYSRLGRGVAFAAVLPAIFVQVPSGLAAQGGISSGIEVATSLTNNTYNTSSSSTLDVNSLKFGLVMVQIAIGISVGLFASALVVYPFGKRRSGLFSF
What are the official names of this protein?
Uncharacterized protein C7D4.12c.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
Protein: YBEY_PSECP
Sequence: MSIEVNNESGVEVDEAGLVALSRYIFEQLYIHPQAELSILLVDEPAMEKLHIELMDEPGATDVLSVPMDDLTPGTPDRPTPQGMLGDIAICPQVAQVQAKNAGHALQDEMLLLTTHGILHLLGYDHAEPEEKEEMFGLQRELLTGFTGKEAPAETTQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T23O_MOUSE
Sequence: MSGCPFAGNSVGYTLKNVSMEDNEEDRAQTGVNRASKGGLIYGNYLQLEKILNAQELQSEVKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVIARMHRVVVIFKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRKHYRDNFGGDYNELLLKSEQEQTLLQLVEAWLERTPGLEPNGFNFWGKFEKNILKGLEEEFLRIQAKTDSEEKEEQMAEFRKQKEVLLCLFDEKRHDYLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDTLMTKWRYNHVCMVHRMLGTKAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLVPRHWVPKMNPIIHKFLYTAEYSDSSYFSSDESD
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: SEM2A_SCHGR
Sequence: MAAKLWNLLLVAASVHLVGSVEQLHQDLIHEFSCGHKYYRTFHLDEKRESLYVGALDKVYKLNLTNISLSDCERDSLTLEPTNIANCVSKGKSADFDCKNHIRVIQPMGDGSRLYICGTNAHSPKDWVVYSNLTHLQRHEYVPGIGVGIAKCPFDPEDSSTAVWVENGNPGDLPGLYSGTNAEFTKADTVIFRTDLYNLTTGRREYSFKRTLKYDSKWLDNPNFVGSFDVGEYVLFFFRETAVEYINCGKSVYSRVARVCKKDVGGKNILSQNWATFLKARLNCSIPGEFPFYFNEIQGVYKMPNTDKFFGVFSTSVTGLTGSAICSFTLKDIQEVFSGKFKEQATSSSAWLPVLPSRVPDPRPGECVNDTELLPDTVLNFIRSHPLMDGAVSHEGGKPVFYKRDVLFTQLVVDKLKVNLVGKNMEYIVYYAGTSTGQVYKVVQWYDSGGLPQSLLVDIFDVTPPEPVQALHLSKEYKSLYAASDNIVRQIELVMCHHRYSNCLQCARDPYCGWDRDSNSCKSYTPGLLQDVTNTSANLCEHSVMKKKLIVTWGQSIHLGCFLKVPEVLSSQTISWVHYTKDKGRYPIVYRPDKYIETSEHGLVLISVTDSDSGRYDCWLGGSLLCSYNITVDAHRCSAPGRSNDYQKIYSDWCHEFERSKIAMKTWERKQAQCSTKQNNSNQKTHPNDIFHSNPVA
What is the function of this protein?
Acts as chemorepulsive guidance molecule critical for axon fasciculation and for determining both the initial direction and subsequent pathfinding events of the Ti axon projection.
What are the official names of this protein?
Semaphorin-2A, Sema-2A, Sema II.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_THEMA
Sequence: MKKRLAVLLVIVLTITFSFSVTTRIKDIAFFRGARDNQLFGIGLVVGLNGTGDSGNVNSPLLLEMMKKFGVQVSENDLKSKNTALVMVLADIPPFAKEGMRIDCVVASIADAKSLAGGYLLQTPLYGADGKVYAVAQGSVIIGGEDVKLSSNLQKRYRVVGYLLEGAIVERDIPSDMLDGDSVTILLRQPDITTAARVARAINEKFEMDLAKAIDPSAIKLTVPSAFQDDLITFLSLVEEIEVQPDVPARIVVNERTGTVLFGGDVKLSDFVISYGNFTISVTGGKIGDKDATISNLVSALKAAGATPQDIIAILQVIYESGYITGELIIM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: NUOK_CAMFF
Sequence: MLDFYILVALILFFIGVLGVILRKNIFTIFMSVELMLNATALIFATFARQSLNLDGQVIVMLIIAIAAAEASFGLALIVLLYKKKQSLNIDIFDELKDRDVS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTL_BUCAT
Sequence: MPIRILPSDLSSQISAGEIIERPASVVKEIIENSIDAGSKNINIIVENSGFQSIILKDDGCGIDKKDLLLAVCHHATSKINSLSDLDKLTTFGFRGEALASIRAVSRLTLISCTRFNDVAAKIYLEGFCSKNIILQPIAHPEGTTIIVDNLFYNIPVRLKFLKNKKLEFSKICEVVKKIALSHFYINFSLKHNNKLITQYNSINNRKNKINRLKDIFDTLDTSEFLEIKEKKYRMVLFGWISHPYNFKKIKNIQYCYVNNRYLYNNIFVNAVRAAYSKIEQKKNISFVLYLTIESFNIDINIHPTKNEIKFHNPDVVYTFIYEAVFSYLKKIKEKYYFNFSCKKQTQLNKEKEFYFYDSDPTFLTLISSIFFKKKQIFKNIKNKIKHNNFISKSTPLEKYESSIGRLLIIIHKYYGLIYHDNNFLLLSFPVAKGIVRKQKLKNNIQKENIIEYFLSNIKINLTSQEYLILFNQKEILSKFGFHLIFKKKYVILSSIPAFLKKCNFHIIISNFFAFLFLKKQVFISDIVDWFYINVFIELKNWTYIRGIEVLLEIEYYCPLLLINPPSKLLQKININAALCILKI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DNAI7_BOVIN
Sequence: MSGSKKKKITKADRLKQILEEEEKRQKEEEEARVKYEKEEMERLEIQRIENEKLQKLEAKDLERRNEELEELYLLEACFPEAEKLKRDNRFLSQWKHYIECDGSPDPSIAQEINTFITLWKEETNETLEEVIEKSKLVLNLIEKLKLILLETPPYDLQGKNIIQYQESILELQELLHLKFNRATEILLRQASTLADLDSGNMEKVIQDENVTLYIWANLKKNPRHRSIRFSETQTGFEIPRILATSDIALRLLHTHYDHVTPLSPVLTPSQEHISIVTDFVKEEVKSVQTAVSKDLQEENKQENESNSVHEEETKAEGQGDVEEQMCPVQEEPEATKYEMEMKLLSETVSAAQELLLENASEKPYFLEENEVDLCQFTTLGGVYHLDILELPPQCKPMKGWMIVEILKEGLQKYTYPPETTEDLEAENVFPPIEVTLEVHENVIFFENPMVARWDAEGKQWKTDGISNVSYKSEERLITFNLETFCPVTLIQDAHINMPYQSWELRPLDVNKVLLTITTVFTELQIQIKENLCMLASIKVNNKNHSSILEEKWMTPVSFIIALKKAGLNIFPTGHSHLYVVINYKHPSVEVKAYRQMALLSSAFAFCWSKWNTACESKKTVFQVREHLLKEEPIRNPNWTLLMFSGDRAQSLKINESSDAFSEALKEETEFHSTLYHMVKDFASQEAMRAVRRSNCQFVDSVCHMLLSTRLLSYS
What is the function of this protein?
Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function.  May act as a cell cycle regulator.
What are the official names of this protein?
Dynein axonemal intermediate chain 7.
What is the protein family that this protein belongs to?
Belongs to the DNAI7 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm. Note=Colocalizes with microtubules in interphase.
Protein: RS10_CORDI
Sequence: MAGQKIRIRLKAYDHEAIDASAKKIVETVTRTGARVVGPVPLPTEKNVYAVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ANDI_EMEVA
Sequence: MEKAVSQFKDFVQSQHHDSYAAIQQADHRGHVVAITGASSGIGKAIAVSYGRCGVSALVLIARRPLDDVKSTVIAASVAAGHSPPEVMTVAANVADETSIYLAATKVKETLGHIDILVNNAGRVGTWGNVEAGEAQDWWQTWEVNIKGVYLTTRAFIPMLLQGKQKTIVNIGSMGVVSPVANLSAYLPSKLALIQFTNIVALEYSSQGLVAFTAYPGDVATELTGSFPEAMSPYFVDTPELPGDSIAWLTQRRLEWLSGRFVSLRWDLPELVSRQSEIVEGDKLRVTMRV
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of anditomin, a fungal meroterpenoid (PubMed:25216349).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase andM (PubMed:25216349).  DMOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHDMP) by the cytochrome P450 monooxygenase andK, which is further prenylated by the prenyltransferase andD to yield farnesyl-DHDMP (PubMed:25216349).  Further epoxidation by the FAD-dependent monooxygenase andE leads to epoxyfarnesyl-DHDMP (PubMed:25216349).  The next step involves the terpene cyclase andB that converts epoxyfarnesyl-DHDMP into preandiloid A through opening of the epoxide ring followed by the cyclization of the farnesyl moiety (PubMed:25216349).  Preandiloid A is in turn oxidized at the C-3 hydroxyl group to yield preandiloid B by the dehydrogenase andC (PubMed:25216349).  The dioxygenase andA is solely responsible for the dehydrogenation of preandiloid B leading to the enone preandiloid C, as well as for the intriguing structural rearrangement to generate the bicyclo[2. 2. 2]octane core, transforming preandiloid C into andiconin (PubMed:25216349).  FAD-binding monooxygenase andJ then produces andilesin D which is reduced by dehydrogenase andI to yield andilesin A (PubMed:25216349).  Action of acetyltransferase andG followed by a spontaneous acetate elimination leads then to andilesin B, which is in turn substrate of the short chain dehydrogenase andH to yield andilesin C (PubMed:25216349).  Finally, the dioxygenase andF catalyzes the transformation of andilesin C to anditomin (PubMed:25216349).
What are the official names of this protein?
Short chain dehydrogenase andI, Anditomin synthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y242_STRZT
Sequence: MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVGYVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL
What are the official names of this protein?
UPF0297 protein SPT_0242.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.