PharMolix/UniProtQA huggingface dataset:
Protein: VSPPA_GLOBR
Sequence: MALIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVVLFNSSGLICSGTLINQEWVLTAAHCDSKNFQMLFGVHSKKILNEDEQTRDPKEKFICPNKKKDDEKDKDIMLIRLDSPVSNSEHIAPLSLPSSSPTVDSVCRIMGWGTIKPADETYPDVPHCANINILDHTVCRAAYPVLLAGSSTLCAGTQQGGKDTCVGDSGGPLICNGQIQGIVSWGAHPCGQGSKPGVYTKVFDHLDWIKSIIAGNTAVTCPP
What is the function of this protein?
Snake venom serine protease that activates plasminogen.  Displays indirect fibrino(geno)lytic activity through conversion of plasminogen to plasmin.  Shows a preferential cleavage at Arg-|-Xaa instead of Lys-|-Xaa bonds.
What are the official names of this protein?
Venom plasminogen activator Haly-PA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
Protein: EF1A_SPOFR
Sequence: HVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSESRFEEIKKEVSSYIKKIGYNPAAVAFVPISGWHGDNMLEASTKMPWFKGWNVERKEGKAEGKCLIEALDAILPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILKPGTIVVFAPANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPKGAADFTAQVIVLNHPGQISNGYTPVLDCHTAHIACKFAEIKEKVDRRTGKSTEDNPKSIKSGDAAIVNLVPSKPLCVESFQEFPPLGRFAVR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_LEGPH
Sequence: MTSKSLNAWVIHKQWSGDTSARLKLFTRELGLINCLCKGGRTPKKQSLLQAFIPLWVSIEERYDQYYTRNIESTSSRLDLEGHSLFSGLYINELLYYTLSPDFPDPDLFDAYLFTLNGIALAREREAIEALLRRFEWALLKACGYTFSFLHEARTGELIVPDSYYQFVAGEGFILGGDKEIPGEHLLAIAADNLSESAYLKSAKFIMRQAINHLLGGREIKARSLYGPA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: THI4_HALMA
Sequence: MSDSDSFEQFSDVGEAEVTRAIGQEWTEEFMDFSDSDVIIVGGGPSGLMAAKELAERGVQVMVVEKNNYLGGGFWLGGFLMNKVTVRDPAQQVLDELEVDHKRSKDSEGLYVANGPEACSGLIKAACDAGAKMQNMTEFTDIVIREDHRVGGIVMNWTPVHALPREITCVDPIAVEADLVIDATGHDAMAVKKLDERGVLNAPGLEDEASGMDQTDDDTYGAPGHDSPGHDSMWVGESEDAVVEHTGLAHDGLVVTGMATATTYGLPRMGPTFGAMLVSGKRAAQVALDELEVDAEPVDVTSRDATPADD
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: SYA_TRIV2
Sequence: MSSNPQHLSGNEIRTRFLDFYAQRGHQILASASLVPEDPTVLLTIAGMLPFKPIFLGQRTPEFKRATTSQKCIRTNDIENVGRTKRHQTFFEMLGNFSFGDYFKEQAIAWGWEISTEVFGLPKERLVVSVFEEDDEAYVIWRDQIGVTEARIKRMGADDNFWVSGPTGPCGPCSEIYYDFHPERGDENIDLEDDTRFIEFYNLVFMQYNRDASGNLTPLQNKNIDTGMGLERITQILQQVPNNYETDLIFPIIETAAKIAGIDYHSSDETTKVSLKVIGDHVRSVVHMIADEIRASNVGRGYVLRRLIRRVVRHGRLIGISGEFINQVAERAIALSESAYPNVRKRETVIKAELEREEANFLKTLDRGEKLLEEIIQQVKKQGQTIISGESAFTLYDTYGFPLELTQEIAEENNLTVDEDDFNVEMQKQVERAKAAHETIDLTVQGSLDKLAEHIHATEFIGYSQATATAKVEVLLVDGVVQEEAEAGTEVQIVLDKTPFYAESGGQIGDRGYISGDGIVVQVEDVKKESDFFVHFGRIERGTLRVGDSVTAQIDRAGRRRAQANHTATHLLQAALKTIVDGGISQAGSLVSFDRLRFDFNSPRGLTAEEIQQVEEQINTWIAEAHSAKIEVLPLAEAKARGAVAMFGEKYGDEVRVIDFPGVSMELCGGTHVSNTAEIGVFKIISEAGVASGVRRIEAVSGLAVLDYLNVRDKVVKDLSDRFKVKPEELPERITTLQNELRTTEKQLETLKGQLAIAKSDSLLQTADTLGDHKIIVAQLEGVDPESLKSAAERLLQKIGNGAVVLGSVPEADKVSLVAAFSPEVNKKGLQAGKFIGAIAKICGGGGGGRPNLAQAGGRDASKLPTALEQAQSELKSALG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_ASPNC
Sequence: MSIEVDWGAATSGPDGEALAERIRSFIHDKFQQVALPRFIRSVQVHSFDFGTIPPELEIKDLCEPFADFYEEDEDDEASDVSEGLVSRHGSPWHGTHPELNESSFRDDNAINHSLRDPFTEGFQPSALRSPIALSDHLNPHFRSGTPGIPGGTSTLGYHLMSLGGLSGTQTPLAAVAGGSPFAGGWNDSGMMGPGNRGRPPPPIFTAHQSRPEADIDSSNPTSRPSTSSTLPSHPSGSNKNNGDGAGGPDHGSHPEEHGHLDDPTSEEPLRFPRMRERRPEDFQVLCHAKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNVTGITFDGVAVVAYIRKRVHFCFLSSEDADALIGSDQPDVGAQTEYSRSGGDATVSAKRQGGLLQEIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFEEELVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ACKA_HAEI8
Sequence: MSKLVLILNCGSSSLKFAILDPATGEEKLSGLAEAFFLPEARIKWKLNGEKGNADLGAGAAHTEALNFIASNILTDELKNSIAAIGHRIVHGGEKYTQSVIVTDEVVKGIEDAAQFAPLHNPAHLIGIREAFNAFPHLKDKNVVVFDTAFHQTMSEEAFLYALPYSLYKEHGVRRYGAHGTSHYFISREVAEYVGKPADQVNAIICHLGNGGSVSVVRNGQCIDTSMGLTPLEGLVMGTRCGDIDPAIVFYLYKTLGMSMEQIEETLVKKSGLLGLTEVTSDCRYAEDNYDNASKPEAKRALNVYSYRLAKYIGAYMAVLGDDHLDAIAFTGGIGENSAHVRELALNHLKLFGIKIDNERNLAARFGKDGVITTDDSAFKAIVLPTNEELVIAQDTARLCF
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_CALS4
Sequence: MIEKIKLTQFTKSAGUAAKIGPEALAQVLCQLEITWNENLLVGLNTNDDAAVYRLNEDIAIVHTVDYFTPVVDDPYDFGQIAAANALSDVYAMGAVPLFALNVVCFPAAYIDVLKEVLRGGNDKVKEAGALIAGGHTIEDEEPKYGLSVTGIVHPEKVIKNSTAKPGDVLILTKPLGIGVINTAIKGEMCPSETYLLAVEVMKYLNKEASEIMKEVGVNACTDITGFGLLGHAYEMAFSSGVTIEFDKDSIPLIEGARELAQMGLIPGGCYRNKKYLKGKVCIKVEEDEVIDLMFDPQTSGGLLISVSEEKAEELYRRLNKKLKFGAFIVGRVKEKQEYDIYVR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: MAOP4_ARATH
Sequence: MISLTPSLFLNKTVVPGCSTRLSLRQPRTIITPPASLRVFSSLGSNQDPTGSVLIETTATSSSSLETSAADIVPKSTVSGGVQDVYGEDAATEDMPITPWSLSVASGYTLLRDPHHNKGLAFSHRERDAHYLRGLLPPTVISQDLQVKKIMHTLRQYQVPLQKYMAMMDLQETNERLFYKLLIDHVEELLPVIYTPTVGEACQKYGSIFLRPQGLFISLKEKGKIHEVLRNWPEKNIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPVTIDVGTNNEKLLNDEFYIGLRQRRATGEEYSELMHEFMTAVKQNYGEKVVIQFEDFANHNAFDLLAKYGTTHLVFNDDIQGTASVVLAGLIAALRFVGGSLSDHRFLFLGAGEAGTGIAELIALEISKKSHIPLEEARKNIWLVDSKGLIVSSRKESIQHFKKPWAHDHEPIRELVDAVKAIKPTVLIGTSGVGQTFTQDVVETMAKLNEKPIILSLSNPTSQSECTAEEAYTWSQGRAIFASGSPFAPVEYEGKTFVPGQANNAYIFPGFGLGLIMSGTIRVHDDMLLAASEALAEELMEEHYEKGMIYPPFRNIRKISARIAAKVAAKAYELGLATRLPQPKELEQCAESSMYSPSYRSYR
What is the function of this protein?
The chloroplastic ME isoform decarboxylates malate shuttled from neighboring mesophyll cells.  The CO(2) released is then refixed by ribulose-bisphosphate carboxylase.  This pathway eliminates the photorespiratory loss of CO(2) that occurs in most plants (By similarity).
What are the official names of this protein?
NADP-dependent malic enzyme 4, chloroplastic, AtNADP-ME4, NADP-malic enzyme 4.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MT2_CHLAE
Sequence: MDPNCSCVAGDSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCNCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: LPXB_VIBC3
Sequence: MNRPLRIGIVVGELSGDTLGEGFIKAIRARYPDAEFVGIGGPKMNALGCQSLFDMEELAVMGLVEVLGRLPRLLKVKAELVKYFTANPPDVFVGIDAPDFNLRLELSLKQAGIKTVHYVSPSVWAWRQNRIHGIAAATHLVLAFLPFEKAFYDKFNVPCEFIGHTLADSIPLASDKLAARQLLGLDEQRRWLAVLPGSRGSEMKMLAEPFIATCQKLQARYPDLGFVVALVNAKRRAQFEQAWQQVAPELNFVLVDDTARNVITAADAVMLASGTVALECMLLKRPMVVGYRVNAFTAFLAKRLLKTPYVSLPNILAGEELVKELLQDHCTVDNLYHEVSRLLESDNQALMDKFTEMHQWIRKDADQQAAQAVLHLIQK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: YF1_MDBVW
Sequence: MAISTNKLFISGSRVSIMSLELIVPNEWNVIPRRTLETELLRIISAKQSVDQTTSGVIGFYNGIVAESRKLSGYLWFRKIGDHSKKPYVNWYQVMTIKPKESPATSSEDISSCSDCDSERLQSDDGCCSTCGEEE
What are the official names of this protein?
Uncharacterized protein F1.
Protein: PSB11_HUMAN
Sequence: MALQDVCKWQSPDTQGPSPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEPEPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome (By similarity).  Plays a pivotal role in development of CD8-positive T cells (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-11, Proteasome subunit beta-5t.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OBG_MYCCT
Sequence: MKFVDSADLIIKAGKGGDGAVSFLHALFVPNGGPNGGDGGDGGSVYFQGDEGKHSLLDLKLQKKYSAQDGFKGDIKNMHGANGEDKIIKVPVGTILYDKKTNTILADINENNKLVLIAKGGKGGKGNARFANSRNKAPTIFEAGELGQEFEIRAELKVLADVGFVGLPNAGKSTLLRAISNSKPVVADYPFTTINPQLGVARTKNNDTFIVADLPGLIQGASLGKGLGHQFLKHIERCLVICHIIDASGNFGSEDIIKNYELIRNELKAYNLNLEKRAEIIVLNKMDLDEAQLNLLDEKIINYFKNKKVVQISGLKKENIDQLLFMIYEELKIAKKQPLWELDKNNDQDEIAIYKFEEQKEDIQVYNKGNNRWEIAGETIFKIYQKFPIWTEDNLLMFNEKLKETGVYETLVKKGIKKGDFVKVFDYELEWTD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTI5_ARATH
Sequence: MSSLLYIFLLLAVFISHRGVTTEAAVEPVKDINGKSLLTGVNYYILPVIRGRGGGLTMSNLKTETCPTSVIQDQFEVSQGLPVKFSPYDKSRTIPVSTDVNIKFSPTSIWELANFDETTKQWFISTCGVEGNPGQKTVDNWFKIDKFEKDYKIRFCPTVCNFCKVICRDVGVFVQDGKRRLALSDVPLKVMFKRAY
What is the function of this protein?
Can inhibit both serine proteases and cysteine proteases (PubMed:30042779).  May be involved in the modulation of the proteases that participate in the hydrolysis of dietary proteins in the gut of spider mites (PubMed:30042779).
What are the official names of this protein?
Kunitz trypsin inhibitor 5, AtKTI5, Kunitz trypsin inhibitor 2, AtKTI2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: GLGB_ALBFT
Sequence: MKSDHDIYLFREGTHAKLYNKLGCHLQSNGGANFAVWAPNAESVSVVGDWNYWSGNVDRLDLRDDGSGIWQGFVENAVRGQGYKYRIQSSHGSYGVDKADPFAFYAEPPPATASRVWSLEHDWKDDQWMSSRGPKNALDAPMSIYEIHLGSWRRQDGHFLDYRELAHSLADYVIEMGFTHVELMPVTEHPFYGSWGYQTTGYFAPTSRFGTPQDFMHFVDHLHQRGIGVLLDWVPSHFPTDEHGLGYFDGTHLFEHSDPRQGFHPEWNSSIFNYGRNEVRSFLISSGLFWLDKYHLDGLRVDGVASMLYLDYARKEDEWIPNRHGGRENLEAVDFLQTLNKAVYREYPDTLTIAEESTAWPRVSRPTDMDGLGFGMKWNMGWMHDSLAYMQQEPVHRKYHHHKLTFSLVYAFNENFVLPLSHDEVVHGKGSLLGKMPGDAWQQFANLRALFGYMWAHPGKKLLFMGGEFGQRREWTHDGELEWWVTKLEGHAGLQRYVAQLNRVYRSLPALYQLDFSPAGFEWVEADAADTSVFAFLRKPREHGAPVLIVSNMTPVPRTNYMLGVPLAGFWREVINSDASEFGGSGWGNLGGVEASPVRFHGRPHSVCLTLPPLSTLIFEHVPHA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: UGTP_STAA1
Sequence: MVTQNKKILIITGSFGNGHMQVTQSIVNQLNDMNLDHLSVIEHDLFMEAHPILTSICKKWYINSFKYFRNMYKGFYYSRPDKLDKCFYKYYGLNKLINLLIKEKPDLILLTFPTPVMSVLTEQFNINIPVATVMTDYRLHKNWITPYSTRYYVATKETKQDFIDVGIDPSTVKVTGIPIDNKFETPINQKQWLIDNNLDPDKQTILMSAGAFGVSKGFDTMITDILAKSANAQVVMICGKSKELKRSLIAKFKSNENVLILGYTKHMNEWMASSQLMITKPGGITITEGFARCIPMIFLNPAPGQELENALYFEEKGFGKIADTPEEAIKIVASLTNGNEQLTNMISTMEQDKIKYATQTICRDLLDLIGHSSQPQEIYGKVPLYARFFVK
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GSTP2_BUFBU
Sequence: SGYTLTYFPLRGRAEAMRLLLGDQGVSWTDDEVQMQDWAAGIRDLKKNAVFGQIPRFQEGDFVLYQSQTILRLLARYGLSGSNEREIAINEMMNDGVEDLRLKYYKFIFWDNEANKEKFLEELATQLGYFERILTNNAGKTFVLVGDKISYADYNLLDTLFCVLDLSPTCLSGFPLLSDYVERLGKRPKLQQYLKSEGRKRRPINGNGKQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase P 2, BBGSTP2-2, GST class-pi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Pi family.
Protein: Y617_TREPA
Sequence: MCSFEHGGWYVPKTVLSLLRRRKCQDARAESEELGITGICQNYAVPVQLGVQHYFGAHWGIDATATVSFGVDTKLAKFRIPYTLRVGPVFRT
What are the official names of this protein?
Uncharacterized protein TP_0617.
Protein: SSRP_THEPX
Sequence: MAKEEIKIIAQNKKAYHDYFIEETYEAGIVLSGTEVKSIRMGKVNLKDSFARVENNEVYLYNMHISPYEKGNIFNKDPLRTRKLLLNRHEINKLIGYVTRKGYTLIPTKLYLKRGLVKVELAVARGKKLYDKREDIARRDAKRELEKHFKEKQLGI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AKIR2_BOVIN
Sequence: MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAATPSSAAAATAASFSAAAASPQKYLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLLSGPASPGTPSGTSSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS
What is the function of this protein?
Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is involved in embryonic development, immunity, myogenesis and brain development (By similarity).  Plays a key role in nuclear protein degradation by promoting import of proteasomes into the nucleus: directly binds to fully assembled 20S proteasomes at one end and to nuclear import receptor IPO9 at the other end, bridging them together and mediating the import of pre-assembled proteasome complexes through the nuclear pore (By similarity).  Involved in innate immunity by regulating the production of interleukin-6 (IL6) downstream of Toll-like receptor (TLR): acts by bridging the NF-kappa-B inhibitor NFKBIZ and the SWI/SNF complex, leading to promote induction of IL6.  Also involved in adaptive immunity by promoting B-cell activation.  Involved in brain development: required for the survival and proliferation of cerebral cortical progenitor cells.  Involved in myogenesis: required for skeletal muscle formation and skeletal development, possibly by regulating expression of muscle differentiation factors (By similarity).
What are the official names of this protein?
Akirin-2.
What is the protein family that this protein belongs to?
Belongs to the akirin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane. Note=Present mainly in the nuclear fraction, and at much lower level in the cytoplasmic and membrane fractions.
Protein: HIS6_SULAC
Sequence: MTSKRIIPCLDVKDGRVVKGVNFLNLVDKGDPVELAARYEEEGADEIVFLDITATIEGRKTMMNVVKDTASVISIPLTVGGGIRSLDDVSKILGNGADKVSINTAAVENKDLVSISSAEFGSQAIVVAIDVKRIGNDYYVFTRSGKYNTGINAISWAKEVEKLGAGEILLTSIDRDGTREGYDIEITELISKSVNIPIIASGGAGKIDDFLGILKVADAALAAGVFHDGVIRIMDLKKYLGKNGVEVRM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HHP1_SCHPO
Sequence: MALDLRIGNKYRIGRKIGSGSFGDIYLGTNVVSGEEVAIKLESTRAKHPQLEYEYRVYRILSGGVGIPFVRWFGVECDYNAMVMDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEFIHSKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLAKKYRDHKTHLHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLVYFCRGSLPWQGLKATTKKQKYEKIMEKKISTPTEVLCRGFPQEFSIYLNYTRSLRFDDKPDYAYLRKLFRDLFCRQSYEFDYMFDWTLKRKTQQDQQHQQQLQQQLSATPQAINPPPERSSFRNYQKQNFDEKGGDINTTVPVINDPSATGAQYINRPN
What is the function of this protein?
Involved in DNA repair.  Has a probable role in repairing alkylated DNA and may regulate the activity of protein(s) involved in double strand break repair caused by gamma rays.
What are the official names of this protein?
Casein kinase I homolog hhp1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y895_HAEIN
Sequence: MYEEIRMKFTDIFIRRPVLAVSISLLMIILGLQAISKLAVREYPKMTTTVITVSTAYPGADANLIQAFVTSKLEESIAQADNIDYMSSTSAPSSSTITIKMKLNTDPAGALADVLAKVNAVKSALPNGIEDPSVSSSSGGSGIMYISFRSKKLDSSQVTDYINRVVKPQFFTIEGVAEVQVFGAAEYALRIWLDPQKMAAQNLSVPTVMSALSANNVQTAAGNDNGYYVSYRNKVETTTKSVEQLSNLIISSNGDDLVRLRDIATVELNKENDNSRATANGAESVVLAINPTSTANPLTVAEKIRPLYESIKTQLPDSMESDILYDRTIAINSSIHEVIKTIGEATLIVLVVILMFIGSFRAILIPILAIPISLIGVLMLLQSFNFSINLMTLLALILAIGLVVDDAIVVLENIDRHIKAGETPFRAAIIGTREIAVPVISMTIALIAVYSPMALMGGITGTLFKEFALTLAGAVFISGVVALTLSPMMSSKLLKSNAKPTWMEERVEHTLGKVNRVYEYMLDLVMLNRKSMLAFAVVIFSTLPFLFNSLSSELTPNEDKGAFIAIGNAPSSVNVDYIQNAMQPYMKNVMETPEVSFGMSIAGAPTSNSSLNIITLKDWKERSRKQSAIMNEINEKAKSIPEVSVSAFNIPEIDTGEQGPPVSIVLKTAQDYKSLANTAEKFLSAMKASGKFIYTNLDLTYDTAQMTISVDKEKAGTYGITMQQISNTLGSFLSGATVTRVDVDGRAYKVISQVKRDDRLSPESFQNYYLTASNGQSVPLSSVISMKLETQPTSLPRFSQLNSAEISAVPMPGISSGDAIAWLQQQATDNLPQGYTFDFKSEARQLVQEGNALAVTFALAVIIIFLVLAIQFESIRDPMVIMISVPLAVSGALVSLNILSFFSIAGTTLNIYSQVGLITLVGLITKHGILMCEVAKEEQLNHGKTRIEAITHAAKVRLRPILMTTAAMVAGLIPLLYATGAGAVSRFSIGIVIVAGLSIGTIFTLFVLPVVYSYVATEHKPLPVFDENKTTH
What is the function of this protein?
Could be a drug efflux pump.
What are the official names of this protein?
Uncharacterized transporter HI_0895.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.