PharMolix/UniProtQA huggingface dataset:
Protein: ARC2A_XENLA
Sequence: MILLEVNNRIIEEILTLKFENAAAGNKPEAVEVTFADFDGVLYHVSNPNGDKAKVLISISLKFYKELQEHGTDEVLKKVYGNFLVAPESGYNVSLLYDLESLPSNKDSVIHQAGMLKRNCFASVFEKYFKFQEEGKDGEKRAVIHYRDDETMYVEAKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNANARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFAAR
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:17178911).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:17178911).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2-A.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: RLMM_STRMK
Sequence: MAPVTDTGIGLLCLCRQGFEPELAGELQFRAGEAGFAGYARTQRNDGYVLFMCDEAAALAPRLRWRELIFARQKLVVLAELPQLDPADRITPMLDVLADAPRFGDLWVEHPDSDAGKPLSGLARAFGNALRPALRKAGKLTDKPNNRLPRLHVVFVDGTHAFVCVADPADSAPWALGIPRLKLLPEAPSRSALKLDEALLTLLMPEEREALAKPGMRAADLGAAPGGWTWVLTRQHMHVLSIDNGPLRQHVLDTGLVEHLRADGFHWHPEQPLDWMVCDMVEQPRRVAERMATWFREGWCRHAIFNLKLPMKKRWDETRLCLDLFQDQAGKPLVVRAKQLYHDREEITVLASPLR
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_LEPBA
Sequence: MAKKSMMERHAKEQKFKVREYNRCPLCGRSRAYLRRFDMCRLCFRDLASKAQIPGVKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NDUA5_PONPY
Sequence: MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMKEWKLWEPLVEEPPADQWKWPI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, Complex I subunit B13, Complex I-13kD-B, CI-13kD-B, NADH-ubiquinone oxidoreductase 13 kDa-B subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PYRB_RUBXD
Sequence: MGARDFLTLEGCDRGELREILELAAGCEAGRMDGALAGKTVCLAFFEASTRTAVSFELAARRCGADVISLSERGSSISKGESLVDTVVTLDRLGADAIVLRHPAAGAARLAARFAAAAVVNAGDGCGQHPTQALLDLYSLSRSVGGFEELAGVRAAVVGDILHSRVARSVIPAFRAAGVELALVAPRTLLPVEAGVWGLPVLSSVDEALEWGASVLYMLRLQRERMTGARVPSVAEYARYYAVGRRHLEAGVRVMHPGPVNRGVEIAGDVVLDGASLIPDQVAAGVAVRSAVLALATGVAQEVAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PFF1_TUBMM
Sequence: MTRVNSIIGFRPIPVTLLTVITYVSLFSALLFIDRQPPAVAKKGELDYWGVDIEEAWSDLEVLTRDFHPYNSRPNDDVRAYLLGRVQEILSRNGVSGFGNELQSSGYSGTVDLFDDGIPGKPGSNVTFVGAGSEDLTVYFEGTNIIVYIHGERPADELSPVLVSAHYDSVSTGYGATDDGAAVVSILQIIKSFTRPESQGGKRPKRGLVALLNNGEEDFLNGARAFAMHPVAKLPHSFLNLEGAGAGGRATLFRSTDAEVTKYYKRAKRPFGTIVSGDGFKAGLIRSGTDYSVFVENLGMRGLDVAFYQPRSRYHTTEDDARHSSKRSLWHMLGGSLATLRGMTDDTSKVFDSPNGSAGKGHNAVWFDLFGRAFSVLHLHTIFAFTITLIVVPFVVVLVAMWALGHFDKLYFFSNTAYIPPPPEHSIASRTTQGWRGVLRFPVAFVAASAGVVGMAFLINKINPMVVYASQYTVWTCFLSTWWIIAWVILRGADAVRPTALARGYGFLEQWLLWLVAMIGVAISIGKSHLGSGYWVLVFYSGFFTSAFISLLEMAALQKKSEVKIAVSGDDQAYPPEEHSQTGASGNISNRAANDDDDAGEHATEETPLFRGPNRPLSFAPHRNPRYDNGDHDSGDILVEEKDEAVYGGEQGWSKDLPSWTWILQFLATVPLQLVLAGSVALLLGNALAQTGADGSDMLTVLLGFGVFSIILLLPVAPFLHRITYHVTLFIFVIFVGTFIYNLAAPPFSPNARLKVYFQQTVDLQTGENNVHLVGHPDYIDRIVSKHIPSAKGKVDICQADKLKSGLRRCSWKGIAPRVVPQAPGGMPPEYGFSDWISYNVTKTGDGKATIKLRGRNTRACKLLFNKPLAKSPTLGNPIPGFPNTRELRLWSRDWERGWSVELTWEKEEDQEENKDSHSSAIVVCLWSDGNKVSDEIPALHEIRRYLPVWAIASKLADGLVEGSVPFMI
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: MUTS_ACET2
Sequence: MASLTPMMQQYLEIKEQYKDCILFFRLGDFYEMFFSDAEVASRELEITLTGKDCGLEERAPMCGVPFHSADSYIAKLISKGYKVAICEQIEDPALAKGLVKRDVIRIVTPGTVTDSAMLDEKKNNYLMSIYKNKNYYGIACVDLTTGEFLSTHITFGNTFNKLMDEIAKFSPSEIVVNGEFFHDENIKKTLKQRFDVYISGLEDKFFEKEFSIQKVRNYFKDYVIEENAFDLYINASGALLEYLEQTQKVNLSHIQNFNVYRIEEYMILDMATRRNLELTETMREKNRKGSLLWVLDRTMTSMGGRTLRKWIEQPLINLHDIKDRLDAVNEFKERFMIRSEVRELLRAVYDIERLMTKVILGSANCRDLISIKHSIGQVPYIKELLRDLKADLNVLSYNELDTLTDVYEIIDKAIVDDPPVAVKEGGIIKEGFNEEVDRLRSASKDGKKWIAHLESKERERTGIKNLKVGFNKVFGYYIEVTKSYYSQVPDDYIRKQTLANCERYITPELKEIENTVLGAEDRLVELEYQIFVDVRNKVAKEINRLKTTARSLARIDVLCSLAEVADRESYTMPEVTDDDKIEIKDGRHPVVEKIIGQEAFVPNDTYLDMDENQIAIITGPNMAGKSTYMRQVALIVLMAQIGSFVPAKSAKIGIVDRIFTRVGASDDLAAGQSTFMVEMSEVANILGNATSKSLLVLDEIGRGTSTYDGLSIAWAVIEYIGEKIGARTLFATHYHELTELEERIEGIKNYCISVEEKGEDIIFLRKILRGGADNSYGVQVARLAGIPDPVIHRAKEILKKLEDADITRKEKRITRRKQPIEGQIDVFTFNAAQRSYDEVLNELKSLDITTLTPLDAINVLYNLQKKVKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MNMG_EHRRW
Sequence: MKKYDVVVIGGGHSGCEAAAAAARIGAKTLLITHSISTIGEMSCNPAIGGIAKGIVVREVDALDGLMGKVIDNASINSTILNRSKGPAVWGPRAQADRDLYRHAMQNSILNYPNLTVLEASVENFTTTDNQELPTINSVITADQEVIYTKKLILTTGTFLQGTIHIGSYNTPAGRFNEQSSVGLAKTLASYNFKLGRLRTGTPPRLDRNSINFSGLQEQKGDTPPSPFSYMSESINLPQISCYLTATNTKTHEVIKNNLHKAAASNLLKEIKAPRYCPSIEEKVRRFSERNSHQVFLEPEGLNSEIIYPNGITTSSPLDVQQTMLKTISGLENVKIVRSGYSVEYNFIDPRELYHTLETKKIRGLYCAGQINGTTGYEEAAGQGIIAGINAALSLNSNYEPFILKRNDAYIGVMIDDLVTLGTSEPYRLFTSRAEYRLRLRSDNADLRLTELGYKVSAVSYQRYLTLNRKKEEVTKLTNILKETVILPSQLSQHGVCISQDGRKRSAFDLLSNPNINMNILSKIFNQIKNYHASTIQQVEIEAKYAPYFIKQELDIQSFIAEENTHIPHDIEFSQIHGLSTEIQEKLQYMKPPSIGSARRIPGVTPAAITNILFYLRYHKNKKIL
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUS1_YEAST
Sequence: MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDTQ
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  The transcription regulatory histone acetylation (HAT) complex SAGA is involved in RNA polymerase II-dependent regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  Within the SAGA complex, participates in a subcomplex with SGF11, SGF73 and UBP8 required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket.  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  SUS1 has also a role in mRNP biogenesis and maintenance of genome integrity through preventing RNA-mediated genome instability.  Has a role in response to DNA damage induced by methyl methane sulfonate (MMS) and replication arrest induced by hydroxyurea.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body. Note=The nucleoplasm localization requires the presence of UBP8 and SGF11 to bind part of SUS1 to the SAGA complex.
Protein: RNB_ECODH
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y635_FERNB
Sequence: MKLTFLGHAVLLISDIEGKYNVIIDPFITGNPAYPKDFQLPKIDYIMVTHGHGDHLGDTVELCKKYNSTVISNFEICNYLQLKGCKIHPMHVGGVYYFEFGKVKLTPAIHGSGIHEGDKVLYGGNPCGFLIKVEGKNIYHAGDTGLTKEFELLKDIDVAFLPIGGNFVMDVEDALVALEMIKPKIVVPIHYNTWDIIKADEQKFKEGAEKLGIKCVILKPGESLEI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Fnod_0635.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RL35_GEOUR
Sequence: MPKIKTHRGAAKRFRKTGTGKIKRNHAFTSHILTSKTRKNKRNLRKGAIVAAVDHKNIAKLIPYM
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RSMH_NITMU
Sequence: MAEAGKHTTVLLQEAVEALALKPDGIYVDGTFGRGGHSRLILERLGKNGRLIAFDRDPVACAVGRSFGDERFCMVHSSYSRLQEVLRQLNIGQIDGVLLDLGVSSPQLEEATRGFSFSMEGPLDMRMDTTEGQTAAQWLASASEVQLEEVIKEYGEERFAKQIARAIVKARARQPLVTTSQLAAIVAAAIPARAREPKQNPATRTFQAIRIYLNQELERLSLALPQCVEMLKTGGRLVVISFHSLEDRIVKRFIREGANTDKLPKHLPLRADEVRRFSRASLQMVGKAVRPGVAEVECNPRARSAVMRVAERINTT
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_AGRRK
Sequence: MNAITSAPAERLVRVPLGERAYDILIGPGLIARAGAEIATRLKGRKAAVITDENVAPIYLDALTASLKAAGIQSSSLVLPAGEKTKSFEHLMTVCDAVLTARIERNDAVIALGGGVIGDLSGFAAGIVRRGVRFVQVPTSLLSQVDSSVGGKTGINTHHGKNLVGVFHQPDLVLADTDVLNTLSQREFRAGYAEVAKYGLIDKPDFFAWLEANWQDVFSGGAARIEAIAASCQAKSDVVVADERENGPRALLNLGHTFGHALEAATAYDSRRLVHGEGVAIGMVLAHEFSSRLNLASPDDAKRVDAHLKTVGLPTRMGDIPGELPPAEVLMDAIAQDKKVKSGQLTFILTRGIGQSFVADDVPSSEVLSFLKEKHPQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM75_HUMAN
Sequence: MRPTADSFRLKKGNVFPNFDPCAQALQKSCHFALSFLIGKMGIIILSVCLICTRLLQEGIAQSKCLINVSFSLYSCFIVFVTISQDSETLSLDCDHRLFFSLPFTDPASGGQSQHSWPCPERSKNLPQVSKQLRNRAG
What are the official names of this protein?
Putative protein encoded by LINC02912.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: URK_STAHJ
Sequence: MANTTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQSHLTFEERLETNYDHPFAFDNDLLIENLKDLRNGHAVEVPTYDYTNHTRSNETIAFEPKDVIIVEGIFALENKTLRDMMDVKIYVDTDADLRILRRLVRDTKERGRSMESVINQYLNVVKPMHNQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQTLVSKQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AUSC_PENBI
Sequence: MTISTTTLGSGATTATRKEVEAKYEEERQIQLQSRGMVQDIEITRNASFEQFAKDPWAAPKQVDVETQREKLLQQAHHKIVIIGAGFGGLLFAVRLIQTGKFKANDIILVDSAAGFGGTWYWNRYPGLMCDTESYIYMPLLEETEYMPRNKYASGNEIREHAERIAEKYNLSERAIFRTVVQSLDWEEEEKVWKIAGVKLGKDDECQQPFQLMADFAIMASGAFASPRVPNYPNIFDYKGKLFHTARWDYKYTGGSIENPKMSGLTNKRVAIIGTGATAIQIVPQLARNSRELFVFQRTPAAVDVRNNYPTDPARFKSEIQGDGPGWQRRRQINFNAFTCNEKTLPTDNKVGDGWTRMPSFSVLIGGPQSLEPDYIDEIRPIDMARQSEIRSRVHKLVQSTAIADSLTPWYPGWCKRPCFHDEYLQSFNSSNVQLVDIRHDGISRFTPKGLVANGVEYELDAIILSTGYTVPVTRASPSGRANIAVTGRRGVTMEEKWANGLATLHGVMTRDLPNLFFAGTSQAGACVNLTYALDQNAIHVAHILSEAVKRQPSDCTKLVIQPTHEGEEAWTMEILQRAAGFRGIAGCTPGYLNGYGMDASSLKPEEQMNMARLAAWGQGIASYVDALEGWRSEGQLEGVEMTFLA
What is the function of this protein?
FAD-binding monooxygenase; part of the gene cluster A that mediates the biosynthesis of the fungal meroterpenoid acetoxydehydroaustin (PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (By similarity).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (By similarity).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG then modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:29076725).  The cytochrome P450 monooxygenase then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:29076725).  The hydroxylation catalyzed by ausR permits the second O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:29076725).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end product of the Penicillium brasilianum austinoid biosynthesis clusters is acetoxydehydroaustin (PubMed:29076725).
What are the official names of this protein?
FAD-binding monooxygenase ausC, Austinoid biosynthesis clusters protein C.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: TBCB_YEAST
Sequence: MVRVVIESELVRTEKELPNSLKLRQFKDRLYHVTGVEPEDMEIVVKRQYDNKEIYSTKKGGAYSNEDEDANFLKGEEELIVVVTDSNAQSISNQLATQAEGIPSMEVISEEDYLRRDQSVLRWKMAHGYGRFNAAQQSQRAALAKQDEAYAREQLTAAIGRHCRVTVDGSAPREAILRYVGPLPLDVMGTWCGVEFPEAAGKNDGRINGVTLFGPVAPGHGSFVRPRAVEILSKDEESAEVEDVHDDVESDDEI
What is the function of this protein?
Acts to sequester alpha-tubulin from interaction with beta-tubulin, raising the possibility that it plays a regulatory role in the formation of the tubulin heterodimer.
What are the official names of this protein?
Tubulin-specific chaperone B, Alpha-tubulin formation protein 1, Tubulin-folding cofactor B.
What is the protein family that this protein belongs to?
Belongs to the TBCB family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: AT1B1_PIG
Sequence: MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQSQKTEISFRPNDPQSYESYVVSIVRFLEKYKDLAQKDDMIFEDCGNVPSELKERGEYNNERGERKVCRFRLEWLGNCSGLNDETYGYKDGKPCVIIKLNRVLGFKPKPPKNESLETYPVMKYNPYVLPVHCTGKRDEDKEKVGTMEYFGLGGYPGFPLQYYPYYGKLLQPKYLQPLMAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS
What is the function of this protein?
Involved in cell adhesion and establishing epithelial cell polarity.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines.
Protein: PGK_LACLS
Sequence: MAKLTVKDVELKGKKVLVRVDFNVPIKDGVITNDNRITAALPTIKYILEQGGRAVLFSHLGRVKEEADKAGKSLAPVAKALSEKLGQDVVFPGTTRGAELEAAINELKDGEILLVENTRFEDIDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVEAPERPFVAILGGSKVSDKIGVIENLLSKADKVIIGGGMAYTFLKAQGYEIGTSLVEDDKLDLAKELLEKAAGKLILPLDHKVANAFAGYTEVKETADQNIPAGFMGLDVASKTIADYNTQLEGAKTVVWNGPVGVFENPDFQAGTVGLMEAIVKQPGVKSIIGGGDSAAAAINLGYAEKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_ECOLI
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What is the function of this protein?
In-frame fusions with the ribosome maturation factor rimM suppress mutations in the latter (probably due to increased rimM expression) and are found in translationally active 70S ribosomes.
What are the official names of this protein?
30S ribosomal protein S16, Small ribosomal subunit protein bS16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: CXG1_HUMAN
Sequence: MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANTAQEQQYGSHEENLPADLEALQREIRMAQERLDLAVQAYSHQNNPHGPREKKAKVGSKAGSNKSTASSKSGDGKTSVWI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction gamma-1 protein, Connexin-45, Cx45, Gap junction alpha-7 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: CO4A3_BOVIN
Sequence: GLPGRKGPVGDAGPPGQLGVTGPQGAPGFPGVTIPGQKGDRGPPGSRGNPGMPGPPGPPGSPVEGIKGDKGLMGEPGQRGPPGAIGDMGSPGHPGAPGVPGQPGARGDPGFYGFPGMKGKKGNSGFPGPPGPPGQSGPKGPPGVRGEPGTVKIISLPGSPGPPGSAGEPGMQGEPGPPGPPGDPGPCGPKGKPGEDGPPGTPGPTGEKGNKGCKGEQGPPGSDGLPGLKGKPGDTGPPAAGAVMRGFVFTRHSQTTAIPSCPEGTEPLYSGFSLLFVQGNEQAHGQDLGTLGSCLQRFTTMPFLFCNINDVCNFASRNDYSYWLSTPAMIPMDMAPITGRALEPYISRCTVCEGPAIAIAVHSQTTDIPPCPAGWISLWKGFSFIMFTSAGSEGAGQALASPGSCLEEFRASPFIECHGRGTCNYYSNSYSFWLASLDPKRMFRKPIPSTVKAGELENIISRCQVCMKMRP
What is the function of this protein?
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
What are the official names of this protein?
Collagen alpha-3(IV) chain.
What is the protein family that this protein belongs to?
Belongs to the type IV collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: PUUR_SHIFL
Sequence: MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGNPNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINTGIPHSFSNTSAGICRIISAHTPTTF
What is the function of this protein?
Represses puuD.
What are the official names of this protein?
HTH-type transcriptional regulator PuuR.
Protein: MBD1_ARATH
Sequence: MLPFPAMNLKKSRSENSSVASSGSKIEEQTEKSAEPTTIKVQKKAGTPGRSIDVFAVQCEKCMKWRKIDTQDEYEDIRSRVQEDPFFCKTKEGVSCEDVGDLNYDSSRTWVIDKPGLPRTPRGFKRSLILRKDYSKMDAYYITPTGKKLKSRNEIAAFIDANQDYKYALLGDFNFTVPKVMEETVPSGILSDRTPKPSRKVTID
What is the function of this protein?
Probable transcriptional regulator.
What are the official names of this protein?
Methyl-CpG-binding domain-containing protein 1, AtMBD1, MBD01, Methyl-CpG-binding protein MBD1.
Protein: BAGE1_HUMAN
Sequence: MAARAVFLALSAQLLQARLMKEESPVVSWRLEPEDGTALCFIF
What is the function of this protein?
Unknown.  Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
What are the official names of this protein?
B melanoma antigen 1, B melanoma antigen, Antigen MZ2-BA, Cancer/testis antigen 2.1, CT2.1.
What is the protein family that this protein belongs to?
Belongs to the BAGE family.
What are the subcellular locations of this protein?
Secreted.