PharMolix/UniProtQA huggingface dataset:
Protein: BRI3B_HUMAN
Sequence: MGARASGGPLARAGLLLLLLLLLLLGLLAPGAQGARGRGGAEKNSYRRTVNTFSQSVSSLFGEDNVRAAQKFLARLTERFVLGVDMFVETLWKVWTELLDVLGLDVSNLSQYFSPASVSSSPARALLLVGVVLLAYWFLSLTLGFTFSVLHVVFGRFFWIVRVVLFSMSCVYILHKYEGEPENAVLPLCFVVAVYFMTGPMGFYWRSSPSGPSNPSNPSVEEKLEHLEKQVRLLNIRLNRVLESLDRSKDK
What is the function of this protein?
Involved in tumorigenesis and may function by stabilizing p53/TP53.
What are the official names of this protein?
BRI3-binding protein, I3-binding protein, Cervical cancer 1 proto-oncogene-binding protein KG19, HCCRBP-1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: ATB_ASPTN
Sequence: MAPQLAGSSHSSSASDQAHRQSSDPALESGSDTHVGSIAPKTETDFLVSFTGDDDPRSPKHMSSARKWLIVAIVSSTRLGLSPMILAPLSEFYGRKPVYVVSMFFFVVWIIPCAVARNIETLIVARFFNGFAGAAFLSVAGGTVGDLFPKNKLQAPMMVYTASPFLGPELGPVIGNFINSYLDWRWSFYILLIWAFAQWVSISLLVPETYHPVLLRREAQRLRKETGDDRYYAPIEKMDRSIAQTIIRSCYRPFLLLTLEPMCLLLCLFCSVLLGVLYLFFGAFSLVFKDNHGFNLWQVGLSFLGITVGMIIGISTNPFWHRNFMRLLQNHEAKTGTVGSSEPEFRLPPAVGGAPLVTIGLLWFAWTTYPSVHWIVPIIGSGIFGAGVIMIFSGVFTFLVDAYPLYAASALAANSFSRSMFAAAFPLFGQAMFRNLGYQWAGFLLAMITLLLAPFPYIFYRWGAKIRQHSRYAGAK
What is the function of this protein?
Efflux pump that might be required for efficient secretion of terreic acid (PubMed:25265334).
What are the official names of this protein?
Efflux pump atB, Terreic acid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_SHEDO
Sequence: MTSIDSSELEKHTPMMRQYLTMKAAHPEMLLFYRMGDFYELFYEDAKLASELLGISLTARGKSGGDPIPMAGLPYHAVEGYLAKLVQIGQSVAICEQVGDPATSKGPVERKVVRIVTPGTLTDEALLQEHQDNLLAAIYQGKVGFGYATLDISSGRFVIAELDTQEALEAELQRTRPVELLYSEDFSNLSLINHLKGIRRRPEWEFDFDTSVNLLLQQFGTKDLHGFGISDARLSLQAAGCLMQYVKDTQKTALPHINAIVRFNQADSIILDAATRRNLELTQNLSGGREHTLAWVLDNTATPMGSRMLQRWLHQPLRDNNIIASRHNAVAELIEANLFDELHQQLKSLGDIERIMARLALRSARPRDFARLRQALSLLPELQHTLGQCKTPLLTKLAQLIGEFPAEHELLENAIVDSPPMLIRDGGVIRSGYHSELDEWRALSEGASDYLTELEAREKQATGISTLKVGYNRVHGYYIEVSRLQADKVPLSYQRRQTLKGTERYITPELKVYEEKVLSSQGKALALEKQLWDQLFDLILPKLNELRDFANAAAELDVICCFAERAESLHYTQPQMVSKTGIQINAGRHPVVERVSSTAFIANPVNLDAKRHMLIVTGPNMGGKSTYMRQVALISLMAHIGCFVPADSAVIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATSQSLVLMDEIGRGTSTYDGLSLAWSAAEYLALQIKAMTLFATHYFELTQLPDLIPGANNVHLDAIEHDDTIAFMHAVQEGAASKSYGLQVAALAGVPSHVIQAAKHKLHQLESRDNQASPAVASAPQQQSLSLSPAPMMGEKALNKLTTINPDELSPKQALDLLYELKKLAKS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DNAJ_CHLPN
Sequence: MDYYSILGISKTASAEEIKKAYRKLAVKYHPDKNPGDAAAEKRFKEVSEAYEVLSDPQKRDSYDRFGKDGPFAGAGGFGGAGGMGNMEDALRTFMGAFGGEFGGGSFFDGLFGGLGEAFGMRSDPAGARQGASKKVHINLTFEEAAHGVEKELVVSGYKSCETCSGQGAVNPQGIKSCERCKGSGQVVQSRGFFSMASTCPECGGEGRIITDPCSSCRGQGRVKDKRSVHVHIPAGVDSGMRLKMEGYGDAGQNGAPSGDLYVFIDVESHPVFERRGDDLILELPIGFVDAALGMKKEIPTLLKTEGSCRLTVPEGIQSGTILKVRNQGFPNVHGKGRGDLLVRISVETPQNLSEEQKELLRTFASTEKAENFPKKRSFLDKIKGFFSDFTV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNDC1_RAT
Sequence: MAPEARASPRLLLRAALLLLAALLPVASSAGPPVDHPLKPRHVKLLSANMGLKVTWDPPKDATSRPVEHYNIAYGKSLKSLKSIKVNAETHSFLIKDVEKEVPNKPLRMRVRASDDRLSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRDERSHEIKKLASESVYVVSLQSTNSQGQSQPVYRAALTKRKNAEEDELDVPEDISVRVMSSQSVLVAWVDPLVEKQKRVVASRQYTVRYREKGESARWDYKQVSNRRALVDSLIPDTVYEFAVRISQGERDGKWSASVFQRTPESAPTTAPENLRVWPVNGKPTVVTVSWDALPESEGKVKEYILSYAPALKPFGAKSLTFSGHTTSALVDGLQPGERYLFKIRATNRRGQGPHSKAFIVAIPTTSSTEASVQPNGRDNGKPEKPQQPSSSAPKVAASSQHMPPAKNVKDALSDLKNKIQTNGVAPGRTQLHSKVGELDPQSTEVTGEEELDSLENPRSSRLETLNQKQPLRVPSRSGHGALAPGRTPARAGLPVLSRKEGMDRRGPSLDPHPHPRVEPSASSAYHQLSSTDNDSVDRKEDDQAGSPDPKAASSGSSPKNPGRSRPTSAPSRHAASNMLRDKSRVHPGTKAASSSTSRQSHSSTSEEDSSAQPSRHFPLHRGSSTSPLSRGWKDRQDTHASSSHTTSRTASSSHPSALTEGSEEEDGGADSDRAAEDTIRRAEATAQIQQTRPGLGHFSLIRNKPFTPHSRNPNRFPRLRGPRLQPSVSPQSTSASKVLTRSPSLPASHTRPGSDVYGDGEDEEPLPATVINDRTPSYPRHPISGSSDTLRRGPQRGASLYRKEPIPENSKAAGADVPPGGRSPLSSKAQGFQQSTTDEGAPQTSPASTSRQPSPARPPASRSQPSPGSTVPRRMTPDRSSELSSSQSKDRSLSQPKLSVAHAGHDHPHTANSRGVLPSAPQNQNEGAQSTYEDNSTEIEGPDSRTPTHSARAKDTTPPILKPRQVGSQSWSSDNRPQPSQAGASERPIRPGSTHPRAQVPGRAGVQATSVKKVSPSKRPLPLESQQSVFAEEEEENEGMLKGKEDSLSTSVKKWPSSSSPRDKYADRNLDKDKAAIGLLVQEENTVPGRRPPGSPAIASHPSTRHQPRNPATASPIANTHSWPRYTTRAPSSYSSTTPMLSLRQRMQRRFRTPVSRQPPPPRPVLTPGYNGRPNAEENIPPGSIGKPNGQRIINGPQGTKWVVDLDRGLVLNAEGRYLQDSHGNPLRVRLGGDGRTIVDLGGTPMVSPDGLPLFGQGRHGKPVASAQDKPILSLGGKPLVGLEVVRTTTQVPTTTMPPSTTTTTVPPTTTLPPTTTTTRRTTTTRRTTTTRRPTTTTRATRRTTTTTTTPEPTTPSPTCPPGTLEHRDEAGNLIMGSNGIPECYPEEDDFSGLEIDTALPTEEDYVVYDDDYGLETTRPPTSTMPSTTAATPKVVPEQGTVSSFPEEEFDLAGKRRFVAPYVTYLSKDPAAPCSLTDALDHFQVESLDELIPNDLTKNDLPPQHAPRNITVVAMEGCHSFVIVDWNKAIPGDVVTGYLVYSASYEDFIRNKWSTQTSSVTHLPIENLKPNTRYYFKVQAKNPHGYGPVSPSVSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPGYTDCHGRQYVKRTWYKKFVGVVLCNSLRYKIYLSDNLKDTFYSIGDSWGRGEDHCQFVDSHLDGRTGPQSYVEALPTIQGYYRQYRQEPVSFGHIGFGTPYYYVGWYECGVSIPGKW
What is the function of this protein?
May be an activator of G protein signaling.
What are the official names of this protein?
Fibronectin type III domain-containing protein 1, Activator of G-protein signaling 8.
What are the subcellular locations of this protein?
Secreted.
Protein: YCF12_ZYGCR
Sequence: MNLEVVAQLTVLALIVVSGPLVIGLLALRKGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL1_NANEQ
Sequence: MVSVDQVKKAREGKKRRFTQTFELIFNLKNVDLRKYRLSTYIVLPRGRGKKMPILAIVGPENKELAEKYFDIVLTREDLKQLDKRTAKKLAKRHYHVVAQADLMPELGKSLLGRFLGIRGKMPNPKAGQILPPNLNEKMLEALREKLNNTVRVNVKKHVTFGVPIGTEDMEDEAIAENADTVINEIISQLPQGKQNIDSVYLKLTMGPAVRVL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL10_THENN
Sequence: MLTRQQKEAIVKEMTEIFKRSSLALFADFTGFTVADLTELRSRLREKYNGGARFKVVKNTLLTLSLKDAGYEGYEEFLKGPTAVLYVTDGDPVEAVKIIYNFYKEKNADLSKLKGGFLEGRKFSSEEVEKIAKLPSKEELYAMLVGRVKAPISGLVFVLSGILRNLVLVLNAVKEKKSE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RDRP_ROTSH
Sequence: MGKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELENRCIEFHSKCLENSKNGLSLRKLFVEYNDVIENATLLSILSYSYDKYNAVERKLVKYAKGKPLEADLTVNELDYENNKITSELFPTAEEYTDSLMDPAILTSLSSNLNAVMFWLEKHENDVAEKLKVYKRRLDLFTIVASTINKYGVPRHNAKYRYEYDVMKDKPYYLVTWANSSIEMLMSVFSHDDYLIAKELIVLSYSNRSTLAKLVSSPMSILVALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELNQMLDNMRKAGLVDIPKMIQDWLVDRSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEYTENVDDEMYREYTMLIRDEVVKMLEEPVKHDDHLLRDSELAGLLSMSSASNGESRQLKFGRKTIFSTKKNMHVMDDMANERYTPGIIPPVNVDKPIPLGRRDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLLSYGDVTRFLSNNTMVLYTDVSQWDSSQHNTQPFRKGIIMGLDILANMTNDAKVLQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANSIANLALIKTVLSRISNKHSFATKIIRVDGDDNYAVLQFNTEVTKQMIQDVSNDVRETYARMNAKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKRGQSTQWDQAAILYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLFPSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADEIAASSTFKNYVTRLSEQLLFSKNNIVSRGIALTEKAKLNSYAPISLEKRRAQISALLTMLQKPVTFKSSKITINDILRDIKPFFTVSDAHLPIQYQKFMPTLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVISLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINYGCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEVINYAIKNGSWISLFCNYPKSEMIKLWKKMWNITSLRSPYTNANFFQD
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsRNA formation.  To do so, the polymerase specifically recognizes and binds 4 bases 5'-UGUG-3' in the conserved 3'-sequence of plus-strand RNA templates.  VP2 presumably activates the autoinhibited VP1-RNA complex to coordinate packaging and genome replication.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component (By similarity). Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: NHAA_SHIF8
Sequence: MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLETPVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLLQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLVLKIFLMALAIIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMVVGILCGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: B3GI_DROME
Sequence: MSEVRIRPRQVLILIIVFLVVLMMVHRNGKRTCQGPEYLQAMFVQGDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVRNLLDRAGLEKRSTLLNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRNHVDVDRHSIVFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFPIDMAAFAISMDLFIRNPQATFSYEVQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKTKLAAEEALLKKGQRSDGGMEV
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.  Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I, Beta-1,3-glucuronyltransferase I, Glucuronosyltransferase I, DmGlcAT-I, UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase, GlcUAT-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: Y2037_EXISA
Sequence: MAKDNSFDIVSEMNLEEVKNAIQIAEKEILNRYDFKGSKSEMSLDNGDLVLISDDDYKLEQLKDVLITKLIKRGVPTKNLDYQKVENALGGTVRQRVKLKSGIDKDDAKKINNAIKESKLKVKSQIQDDQIRVTGKSRDDLQAVMQLVRELELSVDAQFTNFR
What are the official names of this protein?
UPF0234 protein EAT1b_2037.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: EXOB_RHILT
Sequence: MAGETVLVVGGAGYIGSHTCLDLANKGYRPVVFDNFSNGHREFVRWGPAEEGDIRDRARLDEVLAKHKPAAILHFAALIEVGESVKDPVSFYENNVIGTLTLLSAAQAAGINAFVFSSTCATYGLPQSVPLDETHRQVPINPYGRTKYIVEQALADYDQYGSLRSVVLRYFNAAGADFEGRIGEWHQPETHAIPLAIDAALGRRQGFKVFGSDYETRDGTCVRDYIHVLDLADAHVRAVEYLLKGGDSVALNLGTGTGTTVKELLGAIEEVSNRPFPVEYIGRREGDSHTLVANNDKARDVLGWVPQYDLSEIIRSAWDWHAKSNQH
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: SYA_STAAS
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIENQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BACAN
Sequence: MIEIEKPKIETVELNEDAKYGKFVIEPLERGYGTTLGNSLRRILLSSLPGAAVTAIQIDGVLHEFSTVEGVVEDVTTIILNLKKLALKIYSEEEKTLEIDVQGEGIVTAADITHDSDVEILNPDLHIATLAKDAHFRVRLTAKRGRGYTPADANKSEDQPIGVIPIDSIYTPVSRVTYQVEKTRVGQVANYDKLTLDVWTDGSIGPKEAISLGAKILTEHLNIFVGLTDEAQNAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELANKTEEDMMKVRNLGRKSLEEVKHKLEELGLGLRKDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MPGP_ECOLC
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVILCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQFTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPTRVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRLD2_BOVIN
Sequence: MSCVLTGVVPLGLVLLLCGAQGFFLPNVTQLEKLLSKYQGDQPHSRTRRAISRADREEILTLHNKLRGQVSPPASNMEYMTWDEELEKSAVAWARECIWEHGPTSLLVSIGQNLAVHWGRPRSPGSHVQSWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQIVWATTNRIGCAVNTCPRMNVWGDVWENAVYLVCNYFPKGNWIGEAPYKTGQPCSECPGKYRGGCKNNLCYQETYGQETETDDMNEVEAAPIPDEKHVWVTPRVIKPKKPKKDSPVNYMTQVVKCDTKMKDKCKGSTCNRYQCPAGCLHSGAKIFGTLFYESASSICRAAIHYGILDDRGGLVDVTRNGKVPFFVKSERNGVQSLSKYKASSSFTVSKVKVQDLDCYTTVAQLCPYEKPGTHCPRVRCPAHCKDEPSYWAPVFGSNIYADTSSICKTAVHAGVIRNESGGYVDVMPVDKKKTYVASLRNGVQSESLRTPRDGKAFRIFAVRQ
What is the function of this protein?
Promotes matrix assembly.
What are the official names of this protein?
Cysteine-rich secretory protein LCCL domain-containing 2.
What are the subcellular locations of this protein?
Secreted.
Protein: SUCC_CAMJE
Sequence: MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENPAEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFGGIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GLIS3_MOUSE
Sequence: MMVQRLGPISPPASQVSTACKQISPSLPRAVNAANLNRPPSDTRSVILQESLVSTTLSLTESQSALSVKQEWSQSYRAFPSLSSSHSSQNGTDLGDLLSLPPGTPVSGNSVSNSLPPYLFGMENSHSPYPSPRHSATRAHSTRSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGPRASPANLSPQSEVYGHFLGVRGSCIPQSCAVASGQKGILVASGGHTLPGYGEDGTLEYERMQQLEHGGLQPGPVNNMVLQPGLPGQDGQTANMLKTERLEEFPASALDLPSALPLPLPPPQGPPPPYHAHPHLHHPELLPHTQSLSLAQTGLEEDGEMEDSGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQQARKKLRSSTELHPDLLTDCLAVQPLQPATSPGDAADHTVGHSPGPGPGPGPGAELYSAPIFASNHSTRSGTAAGAGPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPPTPSPHHISPGRVPAPPSLLQRAQAPHSQQPPGSLLKPYQPETNSSFQPNGIHVHGFYGQLQTFCPPHYPDSQRTVPPSGSCSMVPSFEDCLVPTSMGQAGFDVFHRAFSTHSGITVYDLPSASSSLFGESLRSGPEDPTFLQLSAVDRCPSQLSSVYTEG
What is the function of this protein?
Acts as both a repressor and activator of transcription.  Binds to the consensus sequence 5'-GACCACCCAC-3'.
What are the official names of this protein?
Zinc finger protein GLIS3, GLI-similar 3.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SOP21_ARATH
Sequence: MLELHFEFIDLNQPKMYKFVVCLLTLSFLLLSGLSNTALARVHHESSNPKIGNRVWDQKIFNNVKVRVLPSASRRGPGQTG
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
What are the official names of this protein?
Serine rich endogenous peptide 21, AtSCOOP21, Phytocytokine SCOOP21, Precursor of serine rich endogenous peptide phytocytokine 21.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Protein: LEPA_CHLCV
Sequence: MKEYKLENIRNFSIIAHIDHGKSTIADRLLESTSTVEQREMREQLLDSMDLERERGITIKAHPVTMYYEYNGEVYQLNLIDTPGHVDFSYEVSRSLAACEGALLIVDAAQGVQAQSLANVYLALERDLEIIPILNKIDLPAANPERIRKQIEDYIGLDTTHAIACSAKTGEGISEILEAIIELIPPPKLPEETELKALIFDSHYDPYVGIMVYVRVISGEIKKGDRITFMATKGSAFEVLGVGAFLPEATLIEGSLRAGQVGYFIANLKKVKDVKIGDTVTTVKHPAKVPLDGFKEINPVVFAGIYPIDSSDFDTLKDALGRLQLNDSALTIEQESSHSLGFGFRCGFLGLLHLEIVFERIIREFDLDIIATAPSVIYKIVLKNGKTLFIDNPTAYPDPSIIEHLEEPWVHVNIITPQEYLSSIMNLCLDKRGVCLKTEMLDQHRLVLSYDLPLNEIVSDFNDKLKSVTKGYGSFDYRLGDYRKGSIIKLEILINDEPVDAFSCLVHRDKAEARGRSICEKLVDVIPQQLFKIPIQAAINKKVIARETIRALSKNVTAKCYGGDITRKRKLWEKQKKGKKRMKEFGKVSIPNTAFIEVLKID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MX1_ICTPU
Sequence: MSASLSEQYEEKVRPCIDLIDSLRALGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRSREEDFWHGKIKYKKDHDEDYEEEIQNPADVEKKIREAQDHMAGVGVGISDELISLEVTSADVPDLTLIDLPGIARVAVKGQPENIGEQIKRLIKKFITKQETINLVVVPSNVDIATTEALKMAQEVDPNGERTLGILTKPDLVDKGTEETVVSIIHNEIIYLTKGYMIVRCRGQKEIMDRVSLHEATEKEKDFFKDHPHFSTLYEEGMATIPNLAEKLTLELVHHIELSLPRLEEQIDIKLADSQAELDRYGSGPPTEPAERICFLIDKVTAFTQDTINLTTGEELKNIQHLNIFSSLRRQFALWKMHLDDSGETFKSRIEKEVNEYEEKYRGRELPGFINYKTFEVIVKDQIKQLEEPAIRRLKEISDLIRKGFIQLAQNSFLGFPNLLKMAKTKIECIKQVKESEAETMLRTQFKMELIIYTQDSMYSDTLSTLKVKEEEGERQKVGILPNSYSISCSLYNHSNNRATLEELMRHLKSYYSIASKRLADQLPLVIRYLLLQESAAQLQREMLQLMQDKNAIDHLLKEDHDIGNKRNNLQSRQKRLMEARNYLVKF
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx1, Interferon-inducible Mx1 protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOM20_SCHPO
Sequence: MRRSVIIGSLLATAAVGYAIYFDYKRRNDPHFRKTLKRRYKKVHEAKKQEEKLATKKFDITVEEALQVVASTPVPSSAEEKELFFMQQVARGEQLFQQQPDNIKESAACFYSALKVYPQPVELFAIYERTVPEPIMNLLRAMQAKESIPSVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit tom20, Mitochondrial 20 kDa outer membrane protein, Translocase of outer membrane 20 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.