PharMolix/UniProtQA huggingface dataset:
Protein: LIAS_SORBI
Sequence: MHGRRHLAASLTRALTQAPSRSISSTPSLLQTLDPSVPSPSPPPAAEPGRLAELRRRLQADAPSLGDFAYSVEVGTRQRPLPKPKWMKETVPGGAKYAAIKAKLRELKLHTVCEEARCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPDEPSNVAQAIASWGLEYIVITSVDRDDLPDQGSGHFAETVQKLKALKPEMLIEALVPDFRGDPSCVEKVATSGLHVFAHNIETVEELQRNVRDYRANFKQSIDVLKMAKEYAPPGTLTKTSIMLGCGETPDQVISTMEKVRAAGVDVITFGQYMRPSKRHMPVSEYVTPEAFEKYRALGVEMGFRYVASGPMVRSSYKAGEFYIKAMIEADRSKATTADSSA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PORC_PYRFU
Sequence: MIEVRFHGRGGQGAVTAANILAEAAFLEGKYVQAFPFFGVERRGAPVTAFTRIDNKPIRIKTQIYEPDVVVVLDPSLLDAVDVTAGLKDEGIVIVNTEKSKEEVLEKLKKKPKKLAIVDATTIALEILGLPITNTAILGAVAKATGLVKIESIEEAIKDTFSGELGEKNARAAREAYEKTEVFEL
What are the official names of this protein?
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma.
Protein: MNMA_NOCSJ
Sequence: MRVLAAMSGGVDSAVAAARAAEAGHDVTGIHLALSRNPQSYRSGARGCCTIEDSNDARRAADVIGIPFYVWDLSDRFHEDVVEDFMAEYAAGRTPNPCLRCNEKIKFAAVLDRALGLGFDAVATGHYARLVAGADGLVEMHRAVDHGKDQSYVLGVLDQGQLRHSLFPLGGSTKDEVRREAAERGLLVADKPDSHDICFIADGDNAGWLREKLGDRAPHHEGTIVDDDTGEVLGRHEGSYGFTIGQRKGLRIGRPAPDGRPRFVLDIEPVSGTVTVGPHERLAVHRLRGIRPRWCGTVPDRLSGTVQLRAHGEEHRAVLVRDGDEVDIELLEPAYGIAPGQAAVLYDGSRVVGSATISATDRVAAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_LEPBA
Sequence: MANLKSSKKDIRRTARRKERNGEDRTELRTYARLLIKAIKSGDKTEALTVFSKLSSKLDRAAKTKLIHKKNADRKKSRMALRINSIEAKAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MAFA2_NEIM0
Sequence: MQARLLIPILFSVFILSACGTLTGIPSHGGGKRFAVEQELVAASARAAVKDMDLQALHGRKVALYIATMGDQGSGSLTGGRYSIDALIRGEYINSPAVRTDYTYPRYETTAETTSGGLTGLTTSLSTLNAPALSRTQSDGSGSKSSLGLNIGGMGDYRNETLTTNPRDTAFLSHLVQTVFFLRGIDVVSPANADTDVFINIDVFGTIRNRTEMHLYNAETLKAQTKLEYFAVDRTNKKLLIKPKTNAFEAAYKENYALWMGPYKVSKGIKPTEGLMVDFSDIRPYGNHTGNSAPSVEADNNHEGYGYSNEAVRQHRQGQP
What are the official names of this protein?
Adhesin MafA 3.
What is the protein family that this protein belongs to?
Belongs to the MafA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y009_HAES1
Sequence: MNLQDHFLIAMPHLEDENFQRSVVYICENNEQGSMGLVLTQATDLSIAELCAKMNFMMADEREYSDKLVLLGGPVNLEHGFILHKKTAQEFQHSYKVTDQIYLTTSADIINTFGTAQSPEKYLVTLGCARWEPNQLENEIANNDWLVVPADEDILFDVDISERWFAANQLLGIEHVNFSYQQQMEHS
What are the official names of this protein?
UPF0301 protein HS_0009.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: AZIN2_MOUSE
Sequence: MAGYLSESDFVMVEEGFSTRDLLEELTLGASQATSGKVAAFFVADLGAVVRKHFCFLKHLPRVRPFYAVGCNSSLGVLKVLAELGLGFSCANKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKMVLCIATQDSHSLNHLSLRFGASLKSCRHLLENAKKSHVEVVGVSFHIGSGCPDPQAYAQSIADARLVFQMGEELGHTMNILDLGGGFPGLEGAKVRFEEMASVINSALDLYFPEGCGVDILAELGRYYVTSAFTVAVSIVAKREVLDQASREEQTGAAPKSIVYYLDEGVYGVFNSVLFDNTCPTPALQKKPSADQPLYSSSLWGPAVEGCDCVAEGLWLPQLQVGDWLVFDNMGAYTVDTKSLLGGTQARRVTYAMSRLAWEALRGQLLPAEEDQDAEGVCKPLSCGWEITDTLCVGPVFTPASIM
What is the function of this protein?
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake.  AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:18062773, PubMed:18508777, PubMed:18973822).  Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:16916800, PubMed:24967154).  Participates in the morphological integrity of the trans-Golgi network (TGN) and functions as a regulator of intracellular secretory vesicle trafficking (By similarity).
What are the official names of this protein?
Antizyme inhibitor 2, AzI2, Arginine decarboxylase-like protein, ADC, ARGDC, Ornithine decarboxylase-like protein, ODC-like protein, ornithine decarboxylase paralog, ODC-p.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC antizyme inhibitor subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Membrane. Cytoplasmic vesicle. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network. Cytoplasmic granule. Cell projection, axon. Cell projection, dendrite. Perikaryon. Note=Detected as vesicle-like pattern in neurite outgrowths. Localizes to the vesicular compartments of the secretory pathway, predominantly in the trans-Golgi network (TGN). Localizes with vesicle-associated membrane protein VAMP8 in the vicinity of the plasma membrane within serotonin-containing secretory granules (By similarity). Colocalizes with KDEL receptors in ER-Golgi intermediate compartment (ERGIC). Translocates from the ERGIC structure to the cytoplasm in a antizyme- dependent manner. Localizes with vesicle-associated membrane protein VAMP8 in the vicinity of the plasma membrane within serotonin- containing secretory granules.
Protein: HSCA_AZOSB
Sequence: MALLQIAEPGMSAEPHKHRLAVGIDLGTTNSLVATVRNGLSVCLADEEGRAMLPSIVRYRADGAVQVGHAAAPFQATDPKNTIVSAKRFMGRGLKDVAYVEAMPYDFEDAPGMVRLRTVQGVKSPVEVSAEILRALRERAEASLGGPLTGAVITVPAYFDDAQRQATKDAARLAGLEVLRLLNEPTAAAVAYGLDNAAEGVYAVYDLGGGTFDLSVLKLSRGVFEVLSTNGDAALGGDDFDHRLFCWVLDKARIAPPSTEDARRLQLKAREAKELLTACESAQIQCRLASGEEVDLVVTREAFAEMTAHLVKKTLGPVRKALRDAGLAPEDIKGVVMVGGATRMPHIQRAVAEYFGQEPLNNLDPDKVVALGAAIQANVLAGNRASEDDWLLLDVIPLSLGLETMGGLVEKVVPRNSTLPIARAQEFTTFKDGQTAMAFHVVQGERELVADCRSLARFELRGIPPMAAGAARIRVTFQVDADGLLSVSAREMSSGVEASVLVKPSYGLSDDEISGMLREGMERAGDDMAARALREQQVEADRVIEATEHALAADGSLLNAEERASIDAAIDALRALRAGTDHRAIKAGIDALSRATDEFAARRMDHSIRAALTGHKLDEFQT
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TIG_OPITP
Sequence: MNVQLNSLSDTRKSLVVSLEASEVDAAHQEVVAEFARQARIPGFRPGKAPAAIIAKRFAKDITDEFKQRVVTKAYRDGLEKQKLDVLTVVNVEPGEVAQGKPASVTITVDVRPDFKLPDYVGLPTSVAPSEATEDEVDRVIEGMRAERAEFKVAERPAAKGDYVKLAYEGKIDGKPIAEIAPDKQIYSKVPQTWEEVEGANEGVIPGLGKQLAGLKVGDKKDVEIDFPADFAAVPELAGKKAVYAAEVLEVRERVLPPLDEAFFKAQHVGNLETLKVSVRSEIKRRKEAQNRAEQRRQVTDALTAKVDFPIPESLIESETQTVLRSFIEENMRRGVPQEQFEKDKKELFEGARQAATKRVKSRLVLAKIAEAEKVEVNEQDIDAFIYREAMRTGQKPDKLVKMLTTDREQLRAVQQSIIFDKAIDFLVSKATVTTVQPKG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS7_WOLTR
Sequence: MARRNKARKRKISPDSRYDSVLLMRFINVIMKYGKKSVAEKIVYNALSSAEKEVNERGVSIFETAVENVTPSVEVRSRRIGGATYQVPVEVKKDRAVSLALRWIVKSASAMRKKSGKGFFKCLCSEILDAYNKRGGAFKMCEEKYKMAEANKAFSHLRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KMS2_ARATH
Sequence: MGYGNRASSKTPAISGLREKHQQDLEKLTLTSQPFKTLRLFVVAVFLYVRRWSSYLLANVGWLILFCSIFVAFAALLVTLDGPHVKHVEELSEYTRFGLWWIFLGVASSIGLGSGLHTFVLYLGPHIALFTIKVMQCGRVDLKSAIYDTIQLKRSPSWLDKPCHEFGSPVFSSGVPLSSILPQVQIEAILWGLGTALGELPPYFISRAASLSGGKMKELETCSGDDNGFIAKRVNQIKSWLLSHSQYLNFFTILILASVPNPLFDLAGIMCGQFEKPFWEFFLATLIGKAIIKTHIQTVFIICVCNNQLLDWVENELIYILSFVPGFASALPELTAKLRLMKEKYLIASPPVSSDINVKKWDLSFASVWNGVVWLMLLNFFGQIVTSTAQRYLKKQQEEELDALTNKSSLTSKKSK
What is the function of this protein?
Involved in the early secretory pathway.  Required for the correct export of secretory products from the endoplasmic reticulum (ER) and involved in the maintenance of ER integrity.
What are the official names of this protein?
Vacuole membrane protein KMS2, Protein KILLING ME SLOWLY 2.
What is the protein family that this protein belongs to?
Belongs to the VMP1 family.
Protein: CPDB_YEREN
Sequence: MFKRPLTLSLLASLIALTTSTAQAATVDLRVLETTDLHSNMMDFDYYKDKPTEKFGLVRTASLIEAARQQATNSVLVDNGDLIQGSPLGDYMAAKGLKAGEIHPVYKAMNTLDYAVGNIGNHEFNYGLDYLKKSLAGAKFPYVNANVIDVKTGKPLFQPYLIVDTPVKDRDGKNHNLRIGYIGFGPPQVMIWDKANLTGKVTVDDITETAKKWVPEMRKQGANLVVAIPHSGLSSDPYKTMAENSVYYLSQVPGIDAIMFGHAHAVFPSKDFATIKGADIAQGTLNGIPAVMPGQWGDHLGVVDFVLNNDQGQWQVTQAKAEARPIFDKATQKSLAAENANLMKVLAADHQGTRDFVSQPIGTASDNMYSYLSLIQDDPTVQIVNNAQRAYTEHFIQGDPDLADLPVLSAAAPFKAGGRKNDPASFVEVEKGELTFRNAADLYLYPNTLVVVKASGADVKQWLECSAAQFNQIDVNSSKPQSLINWDSFRTYNFDVIDGVNYEIDVSQPARYDGECALINDKAERIKNLTFNGKPIDPQATFLIGTNNYRAYSGKFAGTGDSHIAFASPDENRAVLSAYISAETKKHGQVTPQADNNWRLATLNSQQPLDIRFETSPSTKAAEFIKQKAQYPMKAMGTDEIGFAVFKIDLQK
What is the function of this protein?
This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation.  Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate (By similarity).
What are the official names of this protein?
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SIC_ARATH
Sequence: MEDSEKRKQMLKAMRMEAAAQNDDDATTGTETSMSTGHLSNPLAETSNHQQDSFETQRFDYYTDPMAAYSSFKKNKTPKQQYISSPSHQGSSPVPPQFPPSVPPGSLCSEYQAQTNHGGFHAAHYEPRGMAHLSPSHRGPPAGWNNNFRPPPVNHSGPPQWVPRPFPFSQEMPNMGNNRFGGRGSYNNTPPQFSNYGRQNANWGGNTYPNSGRGRSRGRGMNTSFGRDGGRRPMEPGAERFYSNSMAEDPWKHLKPVLWKNCSDASSSSSTGQAWLPKSIAPKKSVTSEATHKTSSNQQSLAEYLAASLDGATCDESSN
What is the function of this protein?
Involved in miRNAs and siRNAs biogenesis and thus promotes gene silencing (PubMed:23071326).  Modulates auxin (IAA) transport-related developmental programs by regulating protein phosphatase 2A (PP2As)-driven auxin efflux carrier PIN proteins recycling and polarity (PubMed:26888284).  Required during development (PubMed:23071326, PubMed:26888284).  Necessary for abiotic stress (e. g.  chilling and salt) tolerance (PubMed:23071326).
What are the official names of this protein?
Protein SICKLE, Protein ROTUNDA 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Colocalizes with miRNA biogenesis components in distinct subnuclear bodies (PubMed:23071326). Localized in the nuclei, excluding the nucleolus, in all cells of the root apical meristem. In young cortical cells of the root, localized in the nucleus and cytosol (PubMed:26888284).
Protein: RS11_PSE14
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNGCGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RBL_STRNX
Sequence: SVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEEDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYIKTFQGPPHAIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAXYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLXKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDAVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAAEGNDIIREASKWSPELAAACEVWKEIRFNFQAVDTLDPLKS
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: WAPI_BACS4
Sequence: MILSSFLKIERMSSMHELKFRDLNVEVNEEDTVLLSMTESEIIVLTKKEIDYGAKYINHIVLYCNTDGRFLNSFSIQTNEQVINVQKVDDSFLFLIDKEYEDSVRDVEPNIYLWNPIEGFHQSFYAGRYINSMIIDQNKNLWVGYDETGIFSCVDQEISTRGINKFVLKNGKYELYFHGVSSYVIDQYFSTFVSEDAIYLYYRSMGEDYLQKLNLLGETLERVEVGIECSSCIKNGSSIYLFSRDDDSYNIEKVFKTNDMQNYVEQKISNENNGESLCFTQVASYKDKVAGIDHNNKLFLLNNQSL
What is the function of this protein?
Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system.  Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli.  Does not inhibit WapA from other strains of B. subtilis.  The WapA C-terminus cannot be expressed on its own in E. coli, however it can be cloned in the presence of its cognate immunity protein gene.  Cell contact is probably necessary for growth inhibition.
What are the official names of this protein?
Immunity protein WapI.
Protein: SEC13_YARLI
Sequence: MVTIGNTHDDLIHDAVLDYYGKRLATCSSDKTIKIFEIDGDNHKLVETLRGHEGPVWQVSWAHPKFGSIIASASYDGKVFIWREENGRWTNIAQHQHNASVNSVVWAPQEYGPLLLCASSDGNVSVVEFKEGGNCEATTFAAHDVGANSASWAPPAVSGSLIQPINGKASNNIRIVTGGCDNLVKIWKYDPSSKTYVIEETLSGHKDWVRDVAWSSSVLSKSYIASASQDKTVIVWTQEGNQPWKKKLLQDIPFPDVVWKVSWSLSGNVLAVSGGDNKVTLWKENLTGEWESAGVVEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: NDHI_TRIV2
Sequence: MLKFLKQVGDYAKEAVQAGRYIGQGLSVTFDHMRRRPVTVQYPYEKLIPGERFRGRIHYEFDKCIACEVCVRVCPINLPVVDWEFDKATKKKKLNHYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELATYDRHELNYDSVALGRLPYKVTDDPMVTPLRELVYLPKGVLDPHDLPANAPRAGARPEDLVEKTEA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: TM41B_HUMAN
Sequence: MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
What is the function of this protein?
(Microbial infection) Critical host factor required for infection by human coronaviruses SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, as well as all flaviviruses tested such as Zika virus and Yellow fever virus (PubMed:33382968, PubMed:33338421).  Required post-entry of the virus to facilitate the ER membrane remodeling necessary to form replication organelles (PubMed:33382968).
What are the official names of this protein?
Transmembrane protein 41B, Protein stasimon.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
Protein: RECA_METPP
Sequence: MDASVKTLNTEKAKALQAALAQIEKQFGKGTIMRLGEGEVIDDIEVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVIAEMQKLAGTCAFIDAEHALDSQYAQKLGVNLQELLISQPDTGEQALEIVDALVRSGSVDLIVVDSVAALTPKAELEGEMGDSLPGLQARLMSQALRKLTATIKKSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKRGEEVIGNETKVKVVKNKVSPPFKTAEFDILFGEGVSREGEIIDLGVIAKVIDKSGAWYAYNGEKIGQGKDNSREFLRENPELAHEIENKIRESLGVALLPSIEIEVPKGTKQAAAGA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_SALRD
Sequence: MPRATNKPATRRRRKKILNKAKGYWGRRSKVYKVAKHAVEKGLQYAYRDRRQKKRRFRRLWITRINAATRQHDVSYSQFMGQYRKSDLDMNRKVLADLAVHDPDAFEQIVDHVME
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PRD10_PONAB
Sequence: MDSKDESSHVWPTSAEHEQNAAQVHFVPDTGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPGQVAYVQQDATAQQTPLGGLEAKEEEDEDEDEDTEEDEEEDGEDADLDDWEPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQLGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSSTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSDLEEKQTSALSGGVQVQPPAHSDSLDPQTTSQQQTTQYIITTTTNGNGSSEVHITKP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
PR domain zinc finger protein 10, PR domain-containing protein 10.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBHD_ECOLI
Sequence: MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHVQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YbhD.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: CEF1_NEUCR
Sequence: MPVVKGGVWTNIEDEILKASVSKYGLNQWARVSSLLARKTPKQCKARWNEWLDPSIKKIEWSKEEDEKLLHLAKLMPTQWRTIAPIVGRTANQCLERYQRLLDEAEQREASALGLTGPDGGEAHAPSADDVRKLRPGEVDPDPETKPARPDTIDLDEDEKEMLSEARARLANTQGKKAKRKARERQQEESRRLAALQKRRELKTAGINIKVTTKKQGQMDYNADIPFEKKPVPGFYDTTEEMSRNEYQRAHFDPKKQQVGNKRKGEEDERDGKRRKGDKDPSVQAALKAGQLQKMREAEQSSKRRALVLPAPQVGEGELEEIVKMGMIGERANMLARESDNDATRGLINNYSTLNTNAPIRTPMAPAQEDHIANEIRNIRALTETQSSLLGGENTPLHQGVGSTGFESVAPRKQVMSTPNPLATPLRAAGAGPGATPLRVGQTPLRTPRDTFALNDAGDEMSMVGGTPRDVKMREMSIRHQLKQGLASLPKPKETEWELELPDDQQEPKTAEQLEEDAAERDRREREIREARELLERKRRTQVMQRDLPRPVQVDYQSLLKEASQAEDPVKVLIAREAALLVAHDATKYPLPGAQPTGRALEIQKIDDAALQEAKLQVLMEIKDKPKPEEVQAVWEKSNSSSLLLGLGCYEDDEEEEQISTMQIALEEVIDQIVASAEKGNKLEKKLNLHLGGYKNRAEMLRKKISEAHEALEKANNALGAFKVLQSSEQAAIRNRLAALREEVGFVSTREREAQELYRRTREELDALTLNGPKANGFR
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor cef-1.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATP6_GEOSE
Sequence: MEHKAPLVEFLGLTFNLSDMLMITITCLIVFIIAVAATRSLQLRPTGMQNFMEWVFDFVRGIINSTMDWQTGGRFLTLGVTLIMYVFVANMLGLPFSVHVNGELWWKSPTADATVTLTLAVMVVALTHYYGVKMKGASDYLRDYTRPVAWLFPLKIIEEFANTLTLGLRLFGNIYAGEILLGLLASLGTHYGVLGAVGEHSMMVWQAFSIFVGTIQAFIFTMLTMVYMAHKVSHDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YD221_YEAST
Sequence: MLLPIPDYPCFSIKKEGRPFIDSCFLPLPSFPFPSCENVPLPYIQSTLKFGYLVFFFYITPRRHCNLAPPRWAARIMSYEVGTAPASSSLSSSFFTVTPFCAARSRRGLTVALIAQSRLPESGAAATFGWASCCCNSRKVHSIGHQIWSATVVSGNSVSEEVILNLNEWPRNCANCVYFSSRG
What are the official names of this protein?
Putative uncharacterized protein YDL221W.