PharMolix/UniProtQA huggingface dataset:
Protein: VSI10_XENLA
Sequence: MWTRRWIQFLVLCLHLWVTVEGYLGVFRGDVNETITLSCNNVTELTAWFKDNNSGVVLACDGENSSDGRFSRINGSSLVITMLQIQDEGNYSCSKCSEDKSSQAYIQLKVSSGPYNVLADISPTRTLPNGTIYTSVGSNLSFGCSSNSYPAPDLEIVLQRTDANPEPFPSIKGNNFLQFNLINVASNYQGNYTCSAVNPLSGRKLNSTRQLLVYRPPITSIKCYANNSLGFSKMLLSCSWPGGYPDPLLQWEQDGKIIANESFAANTKDTLVTYLNSSSLRVRQQFQCSGKHLSTKENNMKTCQIQIDLPLLESQPMRTCFTGENVTLSCSVSGAVPSATITWLRNISDPESDIQPGKKYLISQKDSLSYLTILNCSHEEDEGYYTCKAENVLGIKEINVWLTVNKPHNIVGLVTALLLLFLLVVAIITGTVLYCDPQIYLKANPFRSGATDVLVLVDSEDEENEEVFDTAESVQYTDIVPNVPPPAANGHLSKHEVMFHRPPESTSSDLFSEVSDDTGEENQNEEI
What are the official names of this protein?
V-set and immunoglobulin domain-containing protein 10.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: METK_DEIGD
Sequence: MRKFYTSESVSEGHPDKLADFISDSLLDEFLRQEPESRVAVETLVTTGMAVVAGEVRARSAHVDVQKVVREAVQKVGYTRANYGFDAEYSAVLVSIHEQSPEIGGTVDRSEEWRQMTPQERARPENTFSEVGAGDQGLMFGYATDETPELMPLPISLAHRLTRRLAELRKSGALPYLRPDAKAQVTVVRNGEPHEATETHVDTIVISTQHSEDVSQEQIEADMLEHVVRAVIPHELLTPETKFFINPSGRFVIGGPHGDTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSAAYYARYIAKNIVAAGLARRALVEVAYAIGRAHPVSLRVDTYGTGTLSDERLADLVRAHFDARPQAIIAELDLQRPIYAQTAAYGHFGRPEFPWEQTNKAEALRRAAEELKQEA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KV6A3_MOUSE
Sequence: EIVLTQSPAITAASLGQKVTITCSASSSVSYMHWYQQKSGTSPKPWIYEISKLASGVPARFSGSGSGTSYSLTISSMEAEDAAIYYCQQWNYPLITFGAGTKLELKR
What are the official names of this protein?
Ig kappa chain V-VI region TEPC 601/TEPC 191.
Protein: TRYG1_HUMAN
Sequence: MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
What are the official names of this protein?
Tryptase gamma, Serine protease 31, Transmembrane tryptase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DAPA_AFIC5
Sequence: MTAKSKFRGSFTALVTPFKNGGLDEAAFRGLVSWQIAEGTHGLVPVGTTGESPTVTHDEHKQLVEWCVDEAKARVPVIAGAGSNSTAEAIGLAKHAEKVGAAAVLVVTPYYNKPTQEGLYQHFKAVNDAIGIPIIIYNIPGRSVVDMSTDTMKRLFELKNISGVKDATANIARVSAQRAAMGEDFNQLSGEDITALGYMAHGGHGCISVTSNVAPRLCSEFQTACLKGDYATALKIQDKLVPLHTNLFIEANPAPVKYALSLLGKMSNTLRLPMVELSEANREIVRQSMVHAGLLN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y466_BUCAI
Sequence: MNFLELQVTLSFCVIFLLRMLGMFMILPILSKYGMLLDGGNKFLIGLSMGIYGISQVIFQIPFGILSDKFNRKKIILLGLFMFFIGNIISASIHSIWGLIIGRFFQGSGAISGVCMAFLSDLIREENRVKSIAAIGVSFAISFLIAVVSGPIIVHYFGFFSIFWISAFLSIVCMIIVCFFVPFSKKNILKQNKTLHSYKKVLNFVLNKVFFRFYLGVFFLHFLLMIKFTMIPNQFEISGFSLDNHWKVYLGTILISFFVLFLFIFYCKYKYILENIIEICILFILFSEIIFLSAQKNLLFLIISLQIFFISFNFLEVFLSSHLSRQLSNNYRGSIMSIYSTSQFLGIFFGGVFSGWLYSFLNFSQIFYFELFIILLWLIFSFFLRNRFYL
What are the official names of this protein?
Uncharacterized transporter BU466.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EUTC_ENTFA
Sequence: MNEKELKEMIAGILTEMVADNQAVSTATVTAEEKPVTTHVTETTEIEEGLIPDITEVDLRKQLLLKNAVDPEALLKMKAFSPARLGVGRAGTRYMTSSTLRFRADHAAAQDAVFSDVSEDLVKEMNFISTKTICNSKDEYLTRPDYGRQFDEENSEIIRKNTTPKAKIQMVVGDGLSSAAIEANIKEVLPAIKQGLNMYNLDFDNVVFVKYCRVPAMDKIGEITDADVVCLLVGERPGLVTAESMSAYIAYKPTVGMPEARRTVISNIHKGGTPAVEAGAYIAEIIKKMLDKKKSGIDLKEAE
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RL25_MICAN
Sequence: MQVSVECQKRPENINPRALRRQGLIPAVLYGHNGTESISLVVGEKAALTLLKKASVNNTLVDVNVPEMPWTGKALIQEVQSHPWKRNLYHLSFFSVSAHGKLDIVVPIKAIGEAIGTKQGGLIEQFVNEVNVSCIADNIPEVIEFDVSEIGVGQSLLVGDLKMPEGVTLKDDPHTTVFAIVAAKR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RPOC2_CHAGL
Sequence: MSKKTKILYYNQVMDRSGMKNLISRLISYIGVTSASEVLDQLKTIGFNYATKFGISLGIDDLLTTPFKGWFMQDAEKHASISEKHNRYGTIHAVEKLRQLIETWYTTSEYLKQEMSPNFKITDPYNPVHMMSFSGARGNASQVHQLVGMRGLMADPQGQIIDLPIQSNFREGLSLTEYIISCYGARKGVVDTAVRTADAGYLTRRLVEVVQHIVVRKIDCGSIDGIQLKPLKEKKIKNLFGSADRLVGRVLATDLFIDKRCIAKRNQDIGSELAINIINYQKKAILIRSPLTCKSKQWLCQYCYGWSPCYGDMVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGDIAEHVRAPFNGIAFFSETNLQATRSRHGHPAWISKEDIKITIQYEEIEHKLNIPANSLILIKTNQYVKSKQVLAEVRAKIAPLKEQIEKYIYSDLSGEIHWGFPVRHTSEYIYSNLHTVQNTGHIWVVSGNIKNSNKNLLLFYKKGDYILKDFLNKKLNINFQVYNKKLNFYQKSIRNSKKNINNLINSTEFLNINSSAIFATYRYKNTKMNENNPNIFSETNLNKYSLKKFYNFVLEKNQKFISNNTKIASSSIYKHHIENCGIIKYGSIQIKPFPSNFDQDLNTIKEKIKPLKLKYELINSGTIFWIPEYVHTLVCSRSSILVQDGMFIEAGTEIFRGFFMPESGLVQIKSKTNKIHEITIVPGKLLDSIDIFDNLKKQKFFFYPGEEIIPGIKAEVLTYLYLFGVNKQKNKLLLRPAKEFFIEKLRKNPINLIPIFGTKKDIKIALFEFIVYEDGQQVRSKGKIELVQTCLITNIKKGPYSENAKFFSIDVFFKNLRNRFLNFCFSNQTNFEKMLSKRNFHKNLYFCFKTLNNKNKENLANKKNKDSLIQNKGYLQLLETKNTINKNLLFVSRKNQIQILYNKITKEDLKENYKDINTISKIKKTKIYHTDQQVFTIQSFYLLNKNLGLLGNFYKNKLLFQFIFDYNKIKTYKKDLSLDINTNLLKNKNWFLIDESNNFFQLKTRKNQNVKQKKIEKDIRINLGNFFSQNVVLFNTRQLPESGQILYIEKKICVFRLCRPYLATKNAIIYGNYKQIITSGDNFITIVYERFKTRDIIQGLPKVEQLLEARPLNNLSSNLDFGFLDWNTDISRLLGNPWGFFLSSLIIIRQSQLELVNQIQKVYQSQGVQISDKHLEIIVRQMTSRVLTTEENGPNAFLPGELVDLFKAQRMNQILENSLAYKPILLGITRASLNTYSFISEASFQETTKVLTKAALQGRIDWLQGLKENVILGGIIPAGTGYQKILNKKNSNFLENKKEVSIFVQKQKNIKFNILPSNTEVNKKESIQNLLKKLHITYTFQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VP6_ROTSR
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFNFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLRKLSAIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANIQQFEHIVPLRRVLTTATITLLPDAERFSFPRVINSADGATTWFFNPVILRPNNVEVEFLLNGQIINTYQARFGTIVARNFDTIRLSFQLMRPPNMTPAVAVLFPNAQPFEHHATVGLTLRIESAVCESVLADASETLLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: SYE_HORVU
Sequence: MAASNFMGSSARLRVGLLPSVTPRLSRRALATRASADSGGSGPVRVRFAPSPTGNLHVGGARTALFNYLFARSRGGKFVLRVEDTDLERSTKKSEEAVLTDLSWLGLDWDEGPDIGGDFGPYRQSERNALYKEHAQKLMESGAVYRCFCSNEELEKMKETANRMKIPPVYMGKWATASDAEVQQELEKGTPYTYRFRVPKEGSLKINDLIRGEVSWNLNTLGDFVIMRSNGQPVYNFCVTVDDATMRISHVIRAEEHLPNTLRQALIYKALGFAMPLFAHVSLILAPDKSKLSKRHGATSVGQYKEMGYLPQAMVNYLALLGWGDGTENEFFTIDDLVEKFTIDRVNKSGAVFDATKLKWMNGQHLRSLPSDLLIKDFEDQWRSTGILLESESGFAKEAAELLKEGIDLITDADAALCKLLSYPLHETLSSDEAKSVVEDKLSEVASGLISAYDSGELDQALAEGHDGWKKWVKSFGKTHKRKGKSLFMPLRVLLTGKLHGPAMDSTVILVHKAGTSGAVAPQSGFVSLDERFKILKEVNWESLQKQQESPVESAVPAAS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, chloroplastic/mitochondrial, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: FETP_NEIG1
Sequence: MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWAAWTRHQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: EFPL_ECO7I
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SAM13_MOUSE
Sequence: MLSVDMDNKGNGPVGVKNSMENGRPPDPADWAVTDVVNYFRTAGFEEQACAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALKIYEYHVKPLQTKHLKNNSS
What are the official names of this protein?
Sterile alpha motif domain-containing protein 13, SAM domain-containing protein 13.
Protein: ACER_ACIBT
Sequence: MNINQEQLLMFQAVMETGSFSAAARKLGKVPSAVSMSIANLEIDLNLTLFERKGREPTPTAEARVLYEKTAQLLIEMNQWKQHAHALSTGLEPNLTIVVVSELLHTNWTDYVCLLESRFPDLQINIVSAPQEDALQMLLDGSAQLALMFEREHLDNREQFVELKREALIPVISKTHPLASQEHVSYEQILGTRQIVVASRDETLKPELLFSKHYWRTDNHHSACLMILRNLGWGVLPQEMFKENPELNNKLKALDVFDFTPRFEYYVDLVWSRESELGAAARFLIDYIRNKRMQPAP
What is the function of this protein?
Regulates the expression of the AceI transporter (PubMed:29481596).  Binds DNA and chlorhexidine (PubMed:29481596, PubMed:32636271).  Binds to regulatory sites within the intergenic region between the aceI and aceR genes, and affects the interaction between RNA polymerase (RNAP) and promoter DNA both in the presence and in the absence of chlorhexidine (PubMed:29481596, PubMed:32636271).  In the absence of chlorhexidine, prevents transcription of the aceI gene by disrupting interactions between the promoter DNA and RNAP (PubMed:32636271).  In the presence of chlorhexidine, activates expression of aceI (PubMed:29481596, PubMed:32636271).  When AceR interacts with chlorhexidine, it undergoes a conformational change and the tetrameric form either releases the DNA or shifts the position of the DNA-binding region to allow RNAP to bind onto the promoter DNA to proceed with aceI transcription (PubMed:32636271).
What are the official names of this protein?
HTH-type transcriptional regulator AceR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_BURTA
Sequence: MAKDDVIQMQGEVIENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLSRARIVFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_LISMF
Sequence: MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSEMLEEIKPDCVVDFTTPKVGYSNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGALIAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAPSGTAVKTAEMMAETREFVKQGAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSGVALSVRKTKELETLIYGLENILD
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_CHLAD
Sequence: MSLSEAQVRHVARLARIALSDEEVNVMRAQLSAILDYIAMLQEVDVSNVPPTAQVTGLTTVWRPDVVGEMLTQEQALANAPDQQDGMFRVRAVFEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: BCP_XANCP
Sequence: MTDAVLELPAATFDLPLSLSGGTQTTLRAHAGHWLVIYFYPKDSTPGCTTEGLDFNALLPEFDKAGAKILGVSRDSVKSHDNFCAKQGFAFPLVSDGDEALCRAFDVIKEKNMYGKQVLGIERSTFLLSPEGQVVQAWRKVKVAGHADAVLAALKAHAKQ
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin Bcp, Bacterioferritin comigratory protein, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin Bcp.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
Protein: ISPH_SYNPW
Sequence: MDTHAFKRSLHHSDRYNRRGFGRAEEVAGSLEQAYQSSLIGSIRDNGYRLNHGRLQVRLAKDFGFCWGVERAVAMAYETRKHYPSERLWITNEIIHNPSVNDHLREMNVQFIPVEQGVKDFSGVTSGDVVILPAFGATVQEMQLLNERGCHIVDTTCPWVSKVWNTVEKHKKQTFTSIIHGKVKHEETLATSSFAGTYLVVLDLEEAQIVADYILGNGDRDSFMARFSKACSPGFDPDQDLEKLGVANQTTMLKRETEEIGRLFERTMLSKFGPTQLNEHFLAFNTICDATQERQDAMFSLVDEPLDLMVVIGGYNSSNTTHLQEIAINRGIRSFHIDTPERISADNSIEHKPLGQELIRELEFLPSGTVTVGITSGASTPDRVVEHVIQRLISLSEEN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DNAA_SHIBS
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTIHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTH_ECOLC
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFNLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA
What is the function of this protein?
Confers resistance to norfloxacin and enoxacin.
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEA_PSEAB
Sequence: MRVADFHFDLPEALIARHPLPERRASRLLALDGPTGTLAHRQFADLLDYLRPGDLMVFNNTRVIPARLFGQKESGGKLEVLVERVLDQHRVLAHIRASKAPKPGTRILVEGGGSAEMLQRHDALFELAFAEPVLPLLERVGHMPLPPYIDRPDDAADRERYQTVYAQRAGAVAAPTAGLHFDEALLEAIRAKGVDTAFVTLHVGAGTFQPVRVERIEDHVMHREWLEVGQDVVDAVSACRARGGRVVAVGTTSVRSLESAARDGELKPFSGDTDIFIYPGRPFHVVDALVTNFHLPESTLLMLVSAFAGYPETMAAYAAAVAQGYRFFSYGDAMFITRNPAPRGPED
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MYCSJ
Sequence: MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFFFDLIDAPNHLAGPPDDPRIPEEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTLCGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAATVDLVGEKRAAQLRERTLQIYTQGADHALTKGIIIADTKFEFGVDQSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDKQFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y2806_BURO0
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAQDGQRRLAVAIDARSSASLDEMPGLIRELSREHDVRVLFLNASTQALIQRFSETRRRHPLSGSRSHDADVGLLSSLEEAIERERELVAPLAEFGHQIDTSTLRANALRTWVKRFIEQKNNDLMVMFESFGFKRGVPLDADLMFDVRALPNPYYDHQLRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFRDDNRSYLTVAIGCTGGQHRSVFIAETLAARLARDANVIVRHRDAPVDVDASSRLVSEVDRP
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bcenmc03_2806.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PERC_ECO11
Sequence: MEIRDKKAKYLEEKGFYRRAADRWAEIMVLLSSDAERKLAAQKRAFCINKSLRNNLQADNYSDIKQGVYKAYKKMGLVNEKIFRNYKEN
What is the function of this protein?
Transcriptional activator of eaeA/bfpA expression in enteropathogenic E. coli.
What are the official names of this protein?
Protein PerC, Protein BfpW.
Protein: MEMB_METTR
Sequence: MSQPQSSQVTKRGLTDPERAAIIAAAVPDHALDTQRKYHYFIQPRWKPLSEYEQLSCYAQPNPDWIAGGLDWGDWTQKFHGGRPSWGNESTELRTTDWYRHRDPARRWHHPYVKDKSEEARYTQRFLAAYSSEGSIRTIDPYWRDEILNKYFGALLYSEYGLFNAHSSVGRDCLSDTIRQTAVFAALDKVDNAQMIQMERLFIAKLVPGFDASTDVPKKIWTTDPIYSGARATVQEIWQGVQDWNEILWAGHAVMIATFGQFARREFFQRLATVYGDTLTPFFTAQSQTYFQTTRGAIDDLFVYCLANDSEFGAHNRTFLNAWTEHYLASSVAALKDFVGLYAKVEKSRADRSRRRLRGAAASSAIGRSITPDKIGFRVDVDQKVDAVLAGYKN
What is the function of this protein?
Responsible for the initial oxygenation of methane to methanol in methanotrophs.  It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
What are the official names of this protein?
Methane monooxygenase component A beta chain, Methane hydroxylase.
Protein: ADA_PLAVS
Sequence: MNILQEPIDFLKKEELKNIDLSQMSKKERYKIWKRIPKCELHCHLDLCFSADFFVSCIRKYNLQPNLSDEEVLDYYLFAKGGKSLGEFVEKAIKVADIFHDYEVIEDLAKHAVFNKYKEGVVLMEFRYSPTFVAFKYNLDIELIHQAIVKGIKEVVELLDHKIHVALMCIGDTGHEAANIKASADFCLKHKADFVGFDHGGHEVDLKEYKEIFDYVRESGVPLSVHAGEDVTLPNLNTLYSAIQVLKVERIGHGIRVAESQELIDMVKEKNILLEVCPISNVLLKNAKSMDTHPIRQLYDAGVKVSVNSDDPGMFLTNINDDYEELYTHLNFTLEDFMKMNEWALEKSFMDSNIKDKIKNLYF
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741).  Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine biosynthesis, to produce 5'-methylthioinosine (MTI) (PubMed:19728741).  Plays an essential role in the purine salvage pathway which allows the parasite to use host cell purines for the synthesis of nucleic acids (PubMed:19728741).
What are the official names of this protein?
Adenosine deaminase, S-methyl-5'-thioadenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: YIS3_SHIFL
Sequence: MTKNTRFSPEVRQRAVRMVLESQGEYDSQWATICSIAPKIGCTPETLRVRVRQHERDTGGGDGGLTTAERQRLKELERENRELRRSNDILRQASAYFAKAEFDRLWKK
What are the official names of this protein?
Insertion element IS629 uncharacterized 12 kDa protein S4062.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: NDK1_PARUW
Sequence: MASEQTLSIIKPDAVQNNYIGEIISRFEQAGLKIAAIKMTTLTKDQASKFYAIHKDRPFYNDLVNFMSSGPVVVMVLEGNQAIAKNRELMGATDPKKAEKGTLRADFAESMSRNAVHGSDSSETAEEEVLFFFKPDEITHR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, NDK 1, NDP kinase 1, Nucleoside-2-P kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.