PharMolix/UniProtQA huggingface dataset:
Protein: RS9_PSEA8
Sequence: MSATQNYGTGRRKTATARVFLRPGTGKISINNRGLDQFFGRETARMVVRQPLELTETVEKFDIFVTVVGGGVSGQAGAIRHGITRALIEYDETLRSSLRKAGYVTRDAREVERKKVGLRKARKRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NRDR_CLAM3
Sequence: MFCPFCRHPDSRVVDSRTSDDGLSIRRRRQCPECGRRFSTTETASLSVIKRNGVVEPFSREKIVTGVRKACQGRPVTDTDLAVLAQRVEEAIRATGASQIEANDIGLSILPPLRELDEVAYLRFASVYQGFDSLDDFESAIAQLRVAHAATPDADAL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EFG_RHOJR
Sequence: MAQEVLTDLNKVRNIGIMAHIDAGKTTTTERILFYTGVNYKIGETHDGASTTDWMEQEKERGITITSAAVTCFWNNNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQAAKYDVPRICFVNKMDKMGADFYFTVQTIIDRLGAKPLVLQLPIGAEDDFDGVVDLVEMKAVTWRGTVAIGAEPTIEEIPADLADKAAEYREKLLETVAESDEKLMEKYFAGEELSVEEIKGAIRKMTVNSELYPVLCGSAFKNKGVQPMLDAVIDYLPNPLDIGEVQGHALGNEEEILTRKPSKDEPFSALAFKIASHPFFGKLTFVRVYSGRIDPGAQVMNATKGKKERIGKLFQMHANKENPVDEAVAGHIYAMIGLKDTTTGDTLCAQDAPIVLESMSFPDPVIQVSIEPKTKSDQEKLGTAIQKLAEEDPTFSVELDEETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYRETITKKVEKHDYTHKKQTGGSGQFAKVIIALEPFVGEDGATYEFENKVSGGRIPREYIPSVDAGAQDAMQYGVLAGYPLVNLKLSLLDGAYHDVDSSEMAFKVAGSQALKEAARKAGPVILEPLMAVEVTTPEEYMGDVIGDLNSRRGQIQAMEERSGARVVKALVPLSEMFGYIGDLRSKTQGRANFSMVFDSYAEVPANVSKEIIAKATGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_RHIL3
Sequence: MPVYRSRTTTHGRNMAGARGLWRATGMKDSDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPTVFVSGGPMEAGKVVMHGKTHALDLVDAMVAAADDKISDEDVQTIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHLDRKRLFVEAGHLIVDLARRYYEQDDVKALPRTIASKQAFENAMTLDIAMGGSTNTVLHILAAAHEGEIDFTMADIDALSRRVPCLSKVAPAKSDVHMEDVHRAGGIMSILGELDKGGLLNRDCPTVHAETLGDAIDRWDITRTNSETVRKFYRAAPGGIPTQVAFSQEARWDELDTDRENGVIRSVEHPFSKDGGLAVLKGNLAIDGCIVKTAGVDESILKFSGPARVFESQDASVKAILANEVKAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHASPEAANGGTIGLVREGDMIDIDIPNRTISLRVSETELAARRAEQDAKGWYPTEVRKRNVTTALKAYAAFATSADRGAVRDLNVR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS18_DESPS
Sequence: MAPRPQKKLFTRKKVCRFCADKELVIDYKDVKVLRNFVSERGKIIPRRIVGTCASHQRQLCEAVKRARQIALLPYSGSAQN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYP_DELAS
Sequence: MKASQFFISTLKEAPADAEVVSHKLMTRAGLIKKLGAGIYNYMPMGLRVIRKVEAIVREEMNRAGAVEVTMPVVQPAEMWEETGRFEKMGPELLRIKDRHGRDFVIQPTSEEVVTDIARQELKSYKQLPKNFYQIQTKFRDERRPRFGLMRGREFIMKDAYSFDKDRDTAQISYQTMRAAYKRIFDRFGLQYRAVRADSGAIGGDLSEEFQVIASTGEDAIVYCPSSDYAANIEKAEALAPAGPRPAAAQAMARVATPGNSTCESVAGQLGLPLSQTVKSLVLATDKLDDKGDVAGSQVWLLLLRGDHEMNEIKVAKVPGLDVGFRFATVAEIEEHFGCQPGYLGPIGLKKPVKLVVDREVAVMADWVCGANEADFHITGVNFGRDLPEPDVVADLRNVVAGDKSPDGAGELAIERGIEVGHVFYLGTKYSQAMNATFLAENGKPSLFEMGCYGIGVTRLPAAAIEQNHDERGIIWPDAIAPFTVVVCPIGMDRSEPVKEAAEKLHAELLALGVDVILDDRGERPGAMFADWELIGVPHRVVLSDRGLKEGQVEYQHRRDTEATKMAAADVLGHLKQRLGL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_STRA3
Sequence: MKVIFLQDVKGKGKKGEVKEVPTGYAQNFLLKKNLAKEATTQAIGELKGKQKSEEKAQAEILAQAKELKTQLESETTRVQFIEKVGPDGRTFGSITAKKIAEELQKQYGIKIDKRHIDLDHTIRAIGKVEVPVKLHKQVSSQIKLDIKEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RK18_ARATH
Sequence: MTSVSGCGSVSLITNRSAFLGNGLQHRAVFLKPWSSSSLQSRSMVVEAKTKTSSEDRIARHSRIRKKVNGTTERPRLCVFRSNKHLYVQVIDDTKMHTLASASTKQKPISEEFDYTSGPTIEVAKKVGEVIAKSCLEKGITKVAFDRGGYPYHGRIEALAAAAREHGLQF
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L18, chloroplastic, CL18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HDGR3_MOUSE
Sequence: MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTADLQKAGEGT
What is the function of this protein?
Enhances DNA synthesis and may play a role in cell proliferation.
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 3, HRP-3.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_ANAPZ
Sequence: MVTQKIYIELKAFDHGLLDRSARNIVLVAKRSGAKVNGPIFFPRRTAKFIVNRSTHVDKKSREQFEIRTHKRLISLPKANSAILQALMSLQLPAGVDVKVKVVGG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LRC39_MOUSE
Sequence: MTESAVCTGAVSAVKEVWEERIKKHHEDVKREKEFQHKLVRIWEDRVSLTKLKEKVTREDGRVILRIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQHLIVLDLSRNTISEIPRGIGLLTRLQELILSYNKIKTVPKELSNCTSLEKLELAVNRDISDLPPELSKLLKLTHLDLSMNQFTTIPHAVLDMPALEWLDMGSNSLQQLPDSLDRMRSLHTLWLQRNEITCLPETIKNMKNLGTLVLSNNKLQDIPGCMEEMTNLRFVNFRDNPLRLEVTLPPSDNTDGEEEQELFGLQFMHAYIQESRRTEDQVNCLTQMPSSIHSDGESN
What is the function of this protein?
Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress.  May regulate expression of other M-band proteins via an SRF-dependent pathway.  Important for normal contractile function in heart.
What are the official names of this protein?
Leucine-rich repeat-containing protein 39, Myosin-interacting M-band-associated stress-responsive protein, Myomasp.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: PCDB1_PANTR
Sequence: MAGTRRKSLQNRQVGSLLIFLCISVGGATTIRYSVAEEMESGSFVANVAKDLGLEVGKLAARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPLQSFRAEVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANGYFHLHTRFRSHGPKYAELVLNKPLDREKQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNITLVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSDNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNGEIHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLNILLVDGFSEPYLQFQDPTRHSRKVNPSTKYLVISLVILSFLFLLSVIVIFIIHVYQKIKYREKFTIQEHFYDDCNFSNNLVQGQGNGSLSRPCPYEMCSATGTGNSEFRFLKRFMPNFPFPHATGEIKMEAGSSLPPNSDRNKSQRLEGHDQVSDDYM
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-1, PCDH-beta-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PTXB_STUST
Sequence: MKRLSALLLTCLLSAVSSLSALAADADPDVLKVALLPDENASELIKRNQPLKDYLEEHLDKKVQLIVTTDYSSMIEAMRFGRIDLAYFGPLSYVMAKSKSDIEPFAAMVIDGKPTYRSVIIANVASGVNEYADLKGKRMAYGDRASTSSHLIPKTVLLETADLTGGQDYEQHFVGTHDAVAVNVANGNADAGGLSEVIFNHAAERGLIDPSKVKVLGYSGEYPQYPWAMRSNLSPELKTKVRDVFVGIDDPEVLRNFKAEAFAPITDADYDVIRNMGSLLGLDFATM
What is the function of this protein?
Probably forms part of a binding-protein-dependent phosphite transporter.  Required for oxidation of phosphite to phosphate.
What are the official names of this protein?
Probable phosphite transport system-binding protein PtxB.
What is the protein family that this protein belongs to?
Belongs to the phosphate/phosphite/phosphonate binding protein family.
Protein: SYFA_CHICK
Sequence: MSPSVAELLLQRLERTPPGPEGGLCSLEAAAALGLDHQTLVGAVKSLQALGEVIEAETRATTRWELSAEGEEVLRDGSPEVRLFRSVPSEGLPQSDAMKLPGAQVGFSKAMANKWLRLDKGAPGGPRIFRAVDAVQDVVQSSLRQVQEGNGGSLSERERTDLKRRKLLLEVTLKSYWIRKGSAFSTAVVRQETDLTPEMIATGSWRKLPFKAYNFSALGLPPTCGHLHPLLKVRSQLRQIFLEMGFTEMPTDNFVESSFWNFDALFQPQQHPARDQHDTFFLQDPAEAPELPANYMARVKKVHSQGGYGSQGYKYEWKVEEARKNLLRTHTTSASARALYHLARQGKFTPVKYFSIDRVFRNESLDATHLAEFHQVEGVVADRGLTLGHLMGTLQQFFTKLGISKLRFKPAYNPYTEPSMEVFSYHEGLKKWVEVGNSGVFRS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_BURO1
Sequence: MKKGSAVIKTLRVILSALALCVATSSAHAADTKKVDVLLVGGGIMSSTLGVWLHELQPNWSMTMVERLDGVALESSNGWNNAGTGHSALAELNYTPEKADGKVDISKAIEINESFQISRQFWAWQVKQGVLKNPHSFINSTPHMSFVWGDDNVRFLKKRYEALQASPLFRGMQYSEDYDQIKQWVPLMMEGRDRNQKVAATWTPIGTDVNFGEITRQFVGYLKTQPNFTLSLSSEVREITRNADGTWHVSWVKLHSDEPPQSVDAKFVFIGAGGGALHLLQASGIPEAKDYGAFPVGGSFLVTDNPEVVKQHLAKAYGKASVGSPPMSVPHLDTRIIDGKKIILFGPFATFSTKFLKNGSYFDLAKSTNLHNVAPMMRVGVDEFPLVQYLAGQLMLTDDDRFNALKEYFPNAKKEDWRLWQAGQRVQIIKRDPVKGGVLKLGTEIVASQDGSIAGLLGASPGASTAAPIMLNLMQKVFKDKVATPEWQQKIRQIVPSYGTKLNDSPAKVVEEWTYTSDVLQLSPPPKIDLGAPSQATGNAPARPAKASADMAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: MED31_CRYNJ
Sequence: MQALPTILPPPPLPDDSEAPARTPEKHANLVRFQSELEFIQCLAHPQYLHELHIQGYLGKPAFLNYLKYLEYWREPQYVRFIIYPTCLVYLTLLQTELFRSRLGDMGFITELMRVGSRHHATWRVGKPAEDKQSEEKPAVSMAPLDDDEEEDEPERGQETKGKRKKKKSRSGNVGAGQAL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_PELPB
Sequence: MSDNQDILAVIALTLPDGSVKTFPIGTTGNDVALSIGRKLAQDALALRVNGVAIDLSTPLTADAAIEIITFSSPAGQDIFWHSSSHLMAQAIEELYPGSKFGAGPSIEQGFYYDVASTHRFREEDLRKIEERMLEISKRDIQIRREEMSRTDAIEFFKTVRNDPYKVEILEDTLKEVERVSLYHQDGFTDLCIGPHIPSTSKVKAVLLSNISSSYWRGDSARENMQRIYGITFPSEKLLKEHVARLEEAKRRDHRKLGAELELFMLSPEVGSGLPIWLPKGAIIRNELETFLKEEQRKRGYLPVYTPHIGNIELYKRSGHYPYYSDSQFPPLTYHDEEGKQEQYLLKPMNCPHHHLIYSSKMRSYRDLPLRLTEFGTVYRHEQSGELNGLVRARGFTQDDSHIYCRPDQLVDEICSAIELTQFVFGTLGFSEVQTRLSMHDPENQAKYGGTAEVWEQAEKDVQEAADRMGIDYFIGVGEASFYGPKIDFIVRDALGRKWQLGTVQVDYVMPERFDLTYTGSDGQKHRPVVIHRAPFGSMERFIGVLIEHTAGNFPLWLAPVQAVVLPIAEDVLDYAKSVHQALLAAGIRAELDTRSEKIGKKIRDAEVSKIPCMIVIGQKEQESGEVSLRRHRIGDEGRFSVSGLIEKLKTEITGKS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_MESHJ
Sequence: MKVILIKDTKDGKANTIIDVSPGYATNFLFKNKLAEPLNARTEKLLVKRKQQIEIEKQEKQEQIAKLKIEIEKLVLWFKLKGNKESVHGAITAKKIKKELEIKGIFVDKQAIQTSGISTFGTSFVDIKLSSQTIAKLKINITKDE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TSN6_BOVIN
Sequence: MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIIGFVFRHEIKNSLKNNYEKALKQYNATGDYRSDAVDKIQSMLHCCGVTNYRDWKDTNYYSEKGFPESCCKLEDCSPQRDADKVNNEGCFIMVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV
What are the official names of this protein?
Tetraspanin-6, Tspan-6.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL30_CLONN
Sequence: MAKLKVTLTKSIIGRKKDHIATVNALGLKKIGKSVMHEDTPQIRGMINKVSYLLNVEEI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PUR7_CLOTE
Sequence: MNVVYKGKTKDVFLLEDGNYLLKFKDDVTGENGVFDPGANSVGLTMEGAGRAALRLTKLFFERLKEEKIPTHYIDSNVEEGTMKVKPAKIFGNGLEVICRYRAVGSFMRRYGMYAKEGQVLDAFVEVTLKDDERQDPPITKDALDMLGILSLREYDILKDLTKKISGIVKDELSKKGIELYDIKLEFGRIDEDNHIALIDEISGGNMRAYKDGEYIEPLDLEKLIIE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FIBA_SHEEP
Sequence: ADDSDPVGGEFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: YQXA_BACSU
Sequence: MIAYFGKCLLLVTIMFLGVLFGMQQANHGMLSMKGYHDPSLKGAFTLTDGKDNEKEASILGETVTAKDLVEKQKELEKVETFNMFSKAGKALSDTVTNTAQSMYEWIRDMNQ
What are the official names of this protein?
Uncharacterized protein YqxA, ORF79.
Protein: Y308_HISS2
Sequence: MFGKGGLGNLMKQAQQMQERMQKMQEEIAQLEVTGEAGAGLIKVTINGAHNCRRIDIDPSLMEDDKEMLEDLIAAAFNDAVRRAEEMQKEKMASVTAGMSLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein HSM_0308.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FTHS_VIBVU
Sequence: MLSDIDICRTTPLKPIEQIAAKAGLLADEFETHGLYKAKVSARCVKRLAEQQDGKLVLVTAITPTPLGEGKTVTTIGLAQGLQSLNQSVMACIRQPSMGPVFGVKGGAAGGGYSQVAPMDELNLHLTGDIHAVTAAHNLAAAAIDARIYHEQRAGYQAFEARTGLPALRIDPDRVVWKRVMDHNDRALRKVRVGINDEGKTINGFEREEGFDISAASELMAILALSKNLQDMRERIGKVVLAYNLDSEPVSAEQLQVAGAMTVTLKEAIKPTLMQTLEGVPTLIHAGPFANIAHGNSSIIADEIALKLSSYVVTEAGFGSDMGLEKACNIKSSTSHKAPDCVVIVATLRGLKANSGLYDLKPGMPLPDALFQPDRAALESGFSNLKWHIDNAQKYGLPVVVAINQFPQDSAEELGQLKLWIQQLPLNVRVAISEGFAKGGKGMEAVAREVIEACDAPANFRPLYRAEQTLEEKIITVCTKGYGCGEVQFSDTAKQQLALYQTLGFGELAVCMAKTPLSISSDSSLKGAPSGFTIMVREVRLCAGAGFVYALTGNVMTMPGLPDIPAFMALDIDENGDIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: GRXS2_ORYSJ
Sequence: MQAVAAAAGMMRRGSLTIDPAGEEEAPAERVGRLVRESPVVVFARRGCYMAHVMRRLLAAVGAHATVIELEGGAAEEEEAALGGGAALPALFVGGDPVGGLEGLMGLHLSGRLVPRLREVGALCT
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SALG2
Sequence: MHKQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SYP_LACP3
Sequence: MKQSRMFIPTEKEVPSSAEAKSHKMMLRSGFVRQIQAGVYAYLPLAERVLARIEAIIDDEMTKIDAVKMKMPVLLPAELWEESGRYETYGPNLFKLKNRQDRKMILGPTHEETFTDLVRNELKSYKRMPLVLYQIQDKFRDEDRPRYGVLRGREFIMQDAYSFTSNDQDLDTIYRQMEHAYTNIFDRLGLRYRSIIGDGGAMGGKDSKEFSAIADIGEDTIVYSDSSDYAANLEMATSMALPKQGVEEQAALEPVDTKDAKTIAEVAEFLKVPEKKLIKAVLFMADGAPVLALVRGDYEVNPTKLKNLLNADFLDMATPEQVQTVMHAEVGNIGPVNVDKDVRIIADNSLSDLTNLVAGANKVHTHLLNVNFDRDVTPETYADIRFVTEGEVSPDGQGVLKFTRGIEIGHIFKLGTRYTETMGANFLDENGRSQPIIMGSYGIGVSRLLSAIAEQQADEHGLVWPTTIAPFDIHLIPVNLKREEQKSLTASIETMLEVAGYSVLVDDRNERPGVKFADSDLIGVPLRVTVGKKAVDEIVELKLRKTGETIEVKKEELISSIKILMGQLNKQEQDN
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK13_SPIOL
Sequence: MATMACASSLTFPSAQTQKSFFGTNVKQTPVLSFPRPTVAAAVAVSARKSTSASTKCTEEWRQLKEAVKKEFAIPHVPLDQRWMFTLEEATGPDIWNTTWYPKSADHVPTDKKWYVVDATDLILGRMASTIAIHIRGKNLASYTPSVDMGAFVIVVNADKVAVSGKKRTQKLYRRHSGRPGGLKEETFDQLQKRIPERIIEHAVRGMLPKGRLGRYLFNHLKVYKGAEHPHQAQQPIDLPLRDKRIRVEK
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L13, chloroplastic, CL13, Chloroplastic large ribosomal subunit protein uL13c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IXTPA_PYRAE
Sequence: MRIRLATNNPYKLAEVSHILAPFCIEVERLDAEKVEIQHDDVVVIARKAAEFLCSRYGDFVVVDDTGLYIEALGGFPGPYAEYVYRTIGLKGVLKLLEGAADRRATFKCAAAICIGGRVEVFVGEVRGYIAHEPRGRGGFGYDPIFIPEGMTATYAELGEEVKNKISHRAKAFSQLGAWLTNRNLFK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.