PharMolix/UniProtQA huggingface dataset:
Protein: DING_SALTY
Sequence: MALTAALKAQIAAWYKALQDQIPDFIPRAPQRQMIADVARTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIFSKDLPLLRKIIPDLRFTAAFGRGRYVCPRNLAALASSEPTQQDLLAFLDDELTPNNQEEQKRCARLKGDLDGYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPEPKHLLLVLDEGHHLPDVARDALEMSAEITASWYRLQLDLFSKLVATCMEQFRPKTTPPLANPERLNAHCEEVYELIASLNAILNLYMPAAQEAEHRFAMGELPDEVMEICQRLAKLTETLRGLAESFLNDLSEKTGSHDIVRLHRVILQMNRALGMFEAQSKLWRLASMAQSSGAPVSKWATREIREGQLHVWFHCVGIRVSDQLERLLWRSVPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHVEQGKLVIPQMRYEPTIDNEEQHIAEMAAYFREQLESKKHHGMLVLFASGRAMQRFLEHVADVRLLLLVQGDQPRYRLVELHRKRVESGERSVLVGLQSFAEGLDLKGELLTQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHACRGEVVIYDKRLLTKNYGQRLLNALPVFPIEQPAVPDVIVKPKAKPARRRRR
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase.
What are the official names of this protein?
ATP-dependent DNA helicase DinG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
Protein: Y1952_STAS1
Sequence: MQPDEKEIVKSELLVVTGLSGAGKSVVIQSLEDIGYFCVDNLPPILLPKFVELMGQGNPSLQKVAIAIDLRGKELFKSLIHEMDLIKSNSDVIVDMMFLEASNERLISRYKETRRAHPLNGNGQRSLIESINEERELLTEIKSLANYTIDTTQMKPKELRKRIGDYFNKSNVQTFNINVTSFGFKHGIQMDADLVFDVRFLPNPHYVDELRPLTGEDEAVYKYVMKWKETNIFYEKLIDLLKFMVPGYKKEGKSQLVIAIGCTGGQHRSVALAKRIGAELNESFDYNVYVHHRDAHVESGVKHKDEKN
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SSP1952.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: GRPE_LACAC
Sequence: MSKEEFPSEKNLDKEENTSKPKKAVKKEAAKGEETKKNNENQKLAKEIADLKEKNKDLEDKYLRSEAEIQNMQNRYTKERAQLIKYESQSLAKDVLPAMDNLERALSVEADDDVSKQLKKGVQMTLDALVKAMKDHGVVEIEADGVKFDPTLHQAVQTVAAENDDQKDHVVQVLQKGYQYKDRTLRPAMVVVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_CUPMC
Sequence: MSPAFNASPDQLTLALSKGRIFKETLPLLAAAGIQVTEDPETSRKLILPTSDPAVRVIIVRASDVPTYVQYGAADFGVAGKDVLMEHGMAGLYAPIDLNIARCRMSVAVPAGFDYVNAVRQGARLAVATKYVQTAREHFAKKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGSTLRANNLVEVEEIVQISSRLVVNQAALKLKRERLAPILDAFERASAALA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANFB_SHEEP
Sequence: MDPQKALSRTLLLLLFLHLSLLGCRSHPLGGPGSASELPGLQELLDRLRDRVSELQAEQLRVEPLQQGQGLEETWDSPAAAPAGFLGPHHSLLQALRGPKMMRDSGCFGRRLDRIGSLSGLGCNVLRRY
What is the function of this protein?
Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (By similarity).  May also function as a paracrine antifibrotic factor in the heart (By similarity).  Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses.  Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion.  Binds the clearance receptor NPR3 (By similarity).
What are the official names of this protein?
Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted. Note=Detected in blood.
Protein: RSMC_VIBCH
Sequence: MQPYTAPSEIALRQLDYFADKHVLVAGEVEDRFPIELRQYCASVSVFTTHYGYYSQLKAYPEITRYFGEQLTADLNADLILLYWPKAKQEAEYLLAMLLAKLGTGTEIVVVGENRSGVKSIEKMFAAYGPIHKYDSARRCSFYWGHCVHTPAAFDIEQWFKSYAVDYQGHELTIRSLPGVFSHGEFDLGSRLLLDTLPPLSGKVIDIGSGAGVLGCVMAKLNPHIELEMTDISALAIRSSQETLVANQLHGHVYPSDMFSDTGHHYNYIVTNPPFHSGLETSYSATERLLAESVDHLASGGSIWVVANSFLKYPPILEQAFGHCDIAAKTNKFAIYHAKK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SALCH
Sequence: MKLQLVAVGTKMPDWVQTGYTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLNIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_HELMI
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVRKVDEAYNFIREVATQGKKILFVGTKKQAQDSVKEEAERCGMYYVNQRWLGGMLTNFQTIQKRISRLRELEKMEADGTFEVLPKKEVSKLLHEKEKLERFLGGIKDMKELPGAIFVIDPRKERIAVAEARRLGIPLVGIVDTNCDPDEIDYVIPGNDDAIRAVKLLTAKMADAVLEGNQGQSDAQ
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: EBFC_BORHD
Sequence: MAVNPLDFLKNMTSFKDNIDNLKKEMSQIVVCGRAGSDVIVVEMNGEFLVKKVSIKEEFFSDLDNEALEHMIKSAFNDAISKVKEEIKSKTMGSMPFGI
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein EbfC.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YIHI_ECOBW
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: TM232_MOUSE
Sequence: MKAYKPPVVNKFGVISSTYHEELLKSIFESSNRRKSQKPKPSFSISKEFILRFNHTDNPAEEEELLEQARRLIVRSKRKLGLKTLGSGKHVHLPTAWAEVIYLAQCKGEIQDEALNMLHASLDHVSFDHDQLPALFFLAESVLYRLCCDAFMKGYLYSVEIKLVKIGYLIFLRLFVFFLHGHLESFKQHLLRLQPYLYALHFSEPSYYKYPNIISNVQFILKTSEIICKRELHSEPFVESPDETEDPYSDLNHLQLNKRGYEVNHLLWHSVAAWSCVQNNRPQLTEVLEHLLFYKTQLQTKCWLDSALALMVLGEAAKLDMACLKTLMDLVTDFLENILSAQNQEENYNIYDTSWASEIVFTYTTIIAEVCLYAATSDLRKTALIGFCACKSPQQGISLTDKSEELPELDGASILTLLKYFSSRISDNCEKVIWIGYYGIVYNLVKMSWELQGEQDQDGLRNMIWQTLQKIKDYEQDPRIRCALVIAQAELNGPSDPFCTKATPNSGEEVFSKYIGWRIATTLSRLFFPSLDVAPPKTPVEVDLPRKHTIRERQPAKKRVLRFILKDHSSVVEVSMTPYPNFFTKADKKLEEIIDHHWQKDMEARKREEEAYKAQNQKDKEEKEKIHFQEIMKQRERKLNKQTKPYEIILSEKESGSEKKCGFFELKPSTAPNAK
What are the official names of this protein?
Transmembrane protein 232, Testis-specific protein 13.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CSRA_ECOLC
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: SK1_DELRA
Sequence: GGEEQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_HAEI8
Sequence: MATFNLTIVSAEQKIFEGEVKQIQVTGVEGELGILPGHTPLLTAIKPGIVKFTLKDGNEEVIYVSGGFLEVQPNIVTVLADIAIRGSELDADRIHEAKRKAEENIVSRGSDADHDLLVAKLSKELAKLRAYELTEKLLKTRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DHYS_METS5
Sequence: MRREDILVEEVQDITLDDLRGSSLLEVYNKIYGFSAESIYRGSRILKRIVSECDLRFISFTANLVSTGLRGLFADMIRRGYFNMVVTTGGTIDHDIARSFGGKYYKGSFEFSDEELRKINVHRLGNILIPFEDYGGMVENAVNRILPPLVKEKREWSVYELLWEFGKRIEDKHSILRAAYETNTPIIVPGVVDGSFGTNLFIQSQFTGLRINLFEDMRLIKDRVFSSKMAGALLIGGGISKHHTIWWNQFRDGLDYAVYLTTAQEFDGSLSGARPREAISWNKIRENAEQAVIYADATLALPILATSLIS
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: B1R2_LOXSN
Sequence: FALAHMVNDLEMVDEFVGKGANGLEIDVTFSSSGQPQYTYHGVPCDCFRSCKRREDFDTYIKYIRHLTTPGDPKFRSNLIMLIFDLKLNGLSQDALRKAGVEMADKLVGNYWQDLAEARAYIVLSMPSIEQSAFVTAFKDELKDFGYDKNLDRIGYDFSGNEDLDETAKVYKQLNINGHIWQADGITNCLPRGDSRLKEAISKRDTPGYQYINKVYTWTIDKASSIANALRLGVDGVMTNYPERVIDALNDSEFSGKFRLATYEDNPWETFKG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspiSicTox-betaIE1ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTAP_FUSV7
Sequence: MGDLPTTFDKPVHIAVIGGTGLGQLEGFEPIAALNPITPWGAPASPIQILSHKGVNVAFLARHGIHHQFAPHEVPNRANIAALRHIGVRCVIAFSAVGSLQEEIKPMDFVVPDQVIDRTKGVRPFTFFEGGVVGHVGFADPFDAGLAKVVKTCAEHMEGDGVVLHEKGTVIVMEGPQFSTRAESHMYRSWGGSVINMSTLPEAKLAREAEMAYQVIAMATDYDCWHSFEDVNVEMVGKYMKANSKNAKRLVGAVLDRLADLDNSDLVLAKHWQGASQGAVKFMTKPEGRDPEAMKRVEYLFPGFWEE
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDUB3_MOUSE
Sequence: MAAGHGHEHGHEHGHGHGKMELPDYRQWKIEGTPLETVQKKLAARGLRDPWARNEAWRYMGGFAGNITFPSVILKGFKWGFAAFVVALGAEYFLDSQNGDKKHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3, Complex I-B12, CI-B12, NADH-ubiquinone oxidoreductase B12 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB3 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: RECF_STRR6
Sequence: MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIYFLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQARLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQRNTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEELSISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFGSQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTFITTTSLDHLQNLPENLSIFTIQDGKASVNGN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).  Plays no role in chromosomal or plasmid transformation but is required for resolution of chromosome dimers occurring as intermediates in the formation of merodiploids by transformation (PubMed:25569614).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_ECOBW
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_SHIDS
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: CMOA_PSE14
Sequence: MSKETDRIFAQPLAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPDTVLYDLGSSLGAVTQALRRHVRSEGCEVIAIDNSSAMVERCREYLNAQNSMFQELLPVQVIEGDILALEFKPASVVALNFTLQFIAPEQRLILLGRIRDALVPGGALILSEKLRFDDEQEHALLTDLHIAFKRANGYSDLEIAQKRSAIENVMKPDSLEEHRQRLLAAGFSKVVPWFQCLNFTSLIALP
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: IF3_MYCTO
Sequence: MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_HAES1
Sequence: MIGLVGRKVGMTRIFNEDGVSIPVTVIEIEANRVTQVKTLENDGYTAVQVTTGFKKASRVTKPEAGHFVKAGVEAGRGLWEFRTEGEEFTLGQEINVDIFTDVKKVDVTGTSKGKGFQGGVKRWNFRTQDATHGNSLSHRVLGSIGQNQTPGRVFKGKKMAGHLGAERVTVQSLEIVRVDVERKLLLVKGSVPGATNSDVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RSGA_TRIV2
Sequence: MRVFTTGQLLGTVVAVQANFYKVQLDQDVREPGSRGAGEEVHLDSPLPLYPLSLLLCTRRTRLKKIGQQVMVGDRVVVEEPDWAGGRGAIAEVLSRQTQLDRPPIANADQILLVFAVADPPLEPYQLSRFLVKAETTGLDVVLCLNKSDLVSPEIQQQISDRLLAWGYQPLFISVEKQINIDQIAKYLSNKITVVAGPSGVGKSSLINALIPDINLRVGEVSGKLARGRHTTRHVELFELPNGGLLADTPGFNQPDVDCSPEELVHYFPEARERLAVASCRFNDCLHRDEPDCAVRGDWERYEHYLEFLADAIARQTQLYQQADPESTLKLKTKGKGQSQYEPKLESKKYRRTSRRTQVQGLQDLYQEEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_CLOBL
Sequence: MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLDDTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLINGKPAKKSDPVVLIGAQESYEARCRKCHRVPR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCB2_SACPA
Sequence: MRGLFYLKLLAWVVLLSLCLLMAHRKTKVADKFRALRSRIQSRFNRRIRLNDSFADDLENGLHSRNFDIISENSNDARGGLDDISKNEIKKIMENDNIDFDKARLLYMEKKFGQNGIAPDGTPIDPKAFTFDK
What are the official names of this protein?
UPF0357 protein YCL012C.
What is the protein family that this protein belongs to?
Belongs to the UPF0357 family.
Protein: MAK5_ASPOR
Sequence: MGQKRQRDQKGPGSFAKKRKKSAKPSDATAEDSDWDGIVGMNELNWKEVALPDRLEDAGGFFGLEEIEGVDIIRSEGNGEIKFKKKEPEETNTQSDDEWEGFGDDDQAVSQEESKETQDEPNESDKKAKVKESKNAKKEKKKNAKDARKEQKEKAVESKEDKGIKSGLSFAALQEEEDDGADVSAWESLGLSPEILAGISKMKFTTPTSVQKACIPPILDGRDVIGKASTGSGKTLAFGIPILEYYLEKLRSKTQKDSEKTETTPIALVLSPTRELAHQLAKHIGEVVSHAPGVNARIALLTGGLSLQKQQRVLTNADIVIGTPGRVWEVLSSGHGLIRKMQAIKFLVIDEADRLLSEGHFKEAHEILAALDRVVDGEFPDESSDESDDELDPKSGRQTLVFSATFHRDLQQKLAGKGKWTGGDIMSQKESMEYLLQKLNFREEKPRFIDVNPVSQMAENLKEGIVECAAMEKDLFLYTLLLYHPKHRTLVFTNSISAVRRLTQLLQTLQLPALALHSSMAQKARLRSVERFSSPSSDPSSILVATDVAARGLDIKGIDFVVHYHAPRTADAYVHRSGRTARAGASGKSVIICSPDEMVGVVRLAAKVHANMANRKKVPLESLELDRRVVSRVKQRVTLAARIVDSNIAKEKVSSEDNWLRTAAEDLGVDYDSEEFDNAAARGRGRGRGRQERERKAGSTSKGELAGMRAELKQLLSQRVNVGVSERYLTSGRVDIEALLRGEGNNSFLGQVDPLDF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase mak5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HIS6_BURCH
Sequence: MALAKRIIPCLDVTAGRVVKGVNFVELRDAGDPVEIARRYDDQGADELTFLDITATSDQRDLILPIIEAVASQVFIPLTVGGGVRAVEDVRRLLNAGADKVSMNSSAVANPQLVRDAADKYGSQCIVVAIDAKRVSADGETPRWEVFTHGGRKNTGLDAIEWARKMAELGAGEILLTSMDRDGTKSGFDLALTRGVSDAVPVPVIASGGVGSLQHLADGIKDGRADAVLAASIFHYGEHTVGEAKRFMSDQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBHT_ECOLI
Sequence: MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVTNPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENKHNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAWGGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKNRPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQFCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSAGAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE
What is the function of this protein?
This is one of three E. coli hydrogenases synthesized in response to different physiological conditions.  HYD2 is involved in hydrogen uptake.
What are the official names of this protein?
Hydrogenase-2 small chain, HYD2, Membrane-bound hydrogenase 2 small subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Periplasmic side. Periplasm.