PharMolix/UniProtQA huggingface dataset:
Protein: TYSY_PNECA
Sequence: MVNAEEQQYLNLVQYIINHGEDRPDRTGTGTLSVFAPSPLKFSLRNKTFPLLTTKRVFIRGVIEELLWFIRGETDSLKLREKNIHIWDANGSREYLDSIGLTKRQEGDLGPIYGFQWRHFGAEYIDCKTNYIGQGVDQLANIIQKIRTSPYDRRLILSAWNPADLEKMALPPCHMFCQFYVHIPSNNHRPELSCQLYQRSCDMGLGVPFNIASYALLTCMIAHVCDLDPGDFIHVMGDCHIYKDHIEALQQQLTRSPRPFPTLSLNRSITDIEDFTLDDFNIQNYHPYETIKMKMSI
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: CLPB_THET2
Sequence: MNLERWTQAAREALAQAQVLAQRMKHQAIDLPHLWAVLLKDEGGLAWRLLEKAGADPKALKELQERELSRLPKVEGAEVGQYLTSRLSGALNRAEALMEELKDRYVAVDTLVLALAEATPGLPGLEALKGALKELRGGRTVQTEHAESTYNALEQYGIDLTRLAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIVSLQMGSLLAGAKYRGEFEERLKAVIQEVVQSQGEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYVDEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWEREREILRKLREAQHRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRLEVTEEDIAEIVSRWTGIPVSKLLEGEREKLLRLEEELHKRVVGQDEAIRAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRIDMTEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQKGWPYERIRDEVFKVLQQHFRPEFLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFLAERGYDPVFGARPLRRVIQRELETPLAQKILAGEVKEGDRVQVDVGPAGLVFAVPARVEA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBVR_MYCTU
Sequence: MAMVNTTTRLSDDALAFLSERHLAMLTTLRADNSPHVVAVGFTFDPKTHIARVITTGGSQKAVNADRSGLAVLSQVDGARWLSLEGRAAVNSDIDAVRDAELRYAQRYRTPRPNPRRVVIEVQIERVLGSADLLDRA
What is the function of this protein?
Catalyzes the F420H(2)-dependent reduction of biliverdin-IXalpha at C10 position, leading to bilirubin-IXalpha, a potent antioxidant.  As biliverdin-IXalpha is produced in high amounts in macrophages infected with M. tuberculosis, its reduction by Rv2074 may play a role in protecting mycobacteria against oxidative stress, aiding the persistence of M. tuberculosis infection.
What are the official names of this protein?
F420H(2)-dependent biliverdin reductase, F-BVR.
What is the protein family that this protein belongs to?
Belongs to the F420H(2)-dependent biliverdin reductase family.
What are the subcellular locations of this protein?
Cell surface. Secreted.
Protein: RS4_PSEPG
Sequence: MARYIGPKCKLSRREGTDLFLKSGVRALESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFRGYYQAAASKKGATGENLLQLLECRLDNVVYRMGFGSTRSESRQLVSHKAISVNGKTVNIPSYQVRPGDVVAVREKSLAQLRIVQALELCAQRGRVEWVDVDAAKKSGVFKNVPARSDLSADINENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YR691_MIMIV
Sequence: MSRRKTATKIIDYLEKRINCENIMRYTDEYLDNNSPDKSLVIDEVPVSFTIIPYNANENYSRQLVSTEGDREDKPDFNDIKHMFDVFDFMTEANNTGFEHFPYIYGVLDCLNDIDSTVYVYYEKFDGTLPLLIDNIEHPSDWYDIVFQIVLIIMYIKYVGKMSFKAAPERFLYKKITKPYYKEYSVGDTTLNINHKYLIVCWDTNTTDFEGIQNSESSSENKLPIIDLDFLTEYINVNKDSLKIQPSNRIIKLIQEIKNQPDNIPKILVQYYGPQ
What are the official names of this protein?
Uncharacterized protein R691.
What are the subcellular locations of this protein?
Virion.
Protein: FRE1_CANAL
Sequence: MKIQQLIVFLFAVVLIDARTPKRYSELDIVMSTCTTFIGKYGTVCTSTGKRSTNWNCYCKTDAGFGTISDCLVRGFNNNTNIISKFTESCNMTESKFHAKYDKIQAEFKTNGTEYAKMTTKSSSGSKTSASASKSSKSTGSSNASKSSTNAHGSNSSTSSTSSSSSKSGKGNSGTSTTETITTPLLIDYKKFTPYKDAYQMSNNNFNLSINYGSGLLGYWAGILAIAIFANMIKKMFPSLTNYLSGSISNLFRKHLFLPATFRKKKAQEFSIGVYGFFDGLIPTRLETIIVVIFVVLTGLFSALHIHHVKDNPQYATKNAELGHLIADRTGILGTFLIPLLILFGGRNNFLQWLTGWDFATFIMYHRWISRVDVLLIIVHAITFSVSDKATGKYNTRMKRDFMIWGTVSTICGGFILFQAMLFFRRKCYEVFFLIHIVLVVFFVVGGYYHLESQGYGDFMWAAIAVWAFDRVVRLGRIFFFGARKATVSIKGDDTLKIEVPKPKYWKSVAGGHAFIHFLKPTLFLQSHPFTFTTTESNDKIVLYAKIKNGITSNIAKYLSPLPGNTATIRVLVEGPYGEPSSAGRNCKNVVFVAGGNGIPGIYSECVDLAKKSKNQSIKLIWIIRHWKSLSWFTEELEYLKKTNVQSTIYVTQPQDCSGLECFEHDVSFEKKSDEKDSVESSQYSLISNIKQGLSHVEFIEGRPDISTQVEQEVKQADGAIGFVTCGHPAMVDELRFAVTQNLNVSKHRVEYHEQLQTWA
What is the function of this protein?
Ferric reductase responsible for reducing extracellular iron and copper prior to import.  Catalyzes the reductive uptake of Fe(3+)-salts and Fe(3+) bound to catecholate or hydroxamate siderophores.  Fe(3+) is reduced to Fe(2+), which then dissociates from the siderophore and can be imported by the high-affinity Fe(2+) transport complex in the plasma membrane.  Also participates in Cu(2+) reduction and Cu(+) uptake (By similarity).  Involved in maintenance of cell wall integrity (CWI), mitochondrial function, and interaction between the pathogen and the host.
What are the official names of this protein?
Ferric/cupric reductase transmembrane component 1, Ferric-chelate reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACO11_SPOLI
Sequence: MAQCVQTTTILEQKEEKTVTLLVPQAGKRKFEIVYFNIITFAYWHIAGLYGLYLCFTSTKWATVLFSFFLFVVAEVGVTAGSHRLWSHKTYKAKLPLQILLMVMNSLAFQNTVIDWVRDHRLHHKYSDTDADPHNASRGFFYSHVGWLLVRKHPDVKKRGKEIDISDIYNNPVLRFQKKYAIPFIGAVCFVLPTLIPVYGWGETWTNAWHVAMLRYIMNLNVTFLVNSAAHIYGKRPYDKKILPSQNIAVSIATFGEGFHNYHHVFPWDYRAAELGNNSLNFPTKFIDFFAWIGWAYDLKTVSKEMIKQRSKRTGDGTNLWGLEDVDTPEDLKNTKGE
What is the function of this protein?
Catalyzes the formation of delta(11) fatty acyl precursors in the pheromone gland, and has high activity towards palmitic acid and stearic acid.
What are the official names of this protein?
Acyl-CoA Delta(11) desaturase, Acyl-CoA Delta-11 desaturase, Delta(11)-desaturase, SlsZ/E11.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPE_BURCM
Sequence: MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLLKAHTGTTAGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLSRTELQSLAVKLGADVPFFVFGKNAFAEGIGEELAEVELPTRWFLVVTPRVHVPTAEIFSDELLTRNTKPVTIADFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLYNVTPARMTGSGASVFAAFQSKHEAEAAKAQLPTGWNGAVAESLNEHPLFAFAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: FHLA_SALTY
Sequence: MSYTPMSDLGQQGLFDITRTLLQQPDLASLSEALSQLVKRSALADSAGIVLWQAQSQRAQYYATRENGRPVEYEDETVLAHGPVRRILSRPDALHCNFHEFTETWPQLAASGLYPEFGHYCLLPLAAEGRIFGGCEFIRQEDRPWSEKEYDRLHTFTQIVGVVAEQIQNRVNNNVDYDLLCRERDNFRILVAITNAVLSRLDIDELVSEVAKEIHHYFNIDAISIVLRSHRKNKLNIYSTHYLDEHHPAHEQSEVDEAGTLTERVFKSKEMLLINLNERDPLAPYERMLFDTWGNQIQTLCLLPLMSGKTMLGVLKLAQCEEKVFTTANLKLLRQIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYNVLKQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRSGRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKLIQTDVRLIAATNRDLKKMVADREFRNDLYYRLNVFPIQLPPLRERPEDIPLLVKAFTFKIARRMGRNIDSIPAETLRTLSSMEWPGNVRELENVVERAVLLTRGNVLQLSLPDITAVTPDTSPVATESDKEGEDEYQLIIRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMKRLGIDKDALA
What is the function of this protein?
Required for induction of expression of the formate dehydrogenase H and hydrogenase-3 structural genes.
What are the official names of this protein?
Formate hydrogenlyase transcriptional activator.
Protein: ATPF_ERWT9
Sequence: MNINATILGQAIAFILFVAFCMKYVWPPLMAAIEKRQKEVADGLASAERAKKDLDLAQASATDQLKKAKDDAQVIIEQANKRRAQILDDAKAEAEQERNKIVTQAQAEIDAERKRAREELRKQVAMLAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NADD_PELPD
Sequence: MKIGLMGGTFNPIHMAHLRIAEEARELCGLDRVLFIPVADPPHKPLAGEVPFHQRCQMVRLAIAGNRAFELSEIEGQRPGKSYSIDTIGTFREQHPQAELYFIIGSDSFLELGLWRRYADILRSCNLIVVERPGRQVNDPLSALPVDIRGELRYTPASRSLEHVGGTRVHFFAGCLLDISSSEIRRLAATGRSITYLVPPQVEAYIKEQRIYSECP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ADEC2_BRASO
Sequence: MTNLTRFSVAPLHTMTRRLADVASGRVAPDLVITGARVLSTYSERILRDRELWITGGRVAAVKPAGAHKALPSGFTIYDAAGGIIAPGLVDPHIHIESSMVTACAYAEAALLNGTTTIFCDSHEIGNVMDTAGVEAMLEDARQAPLSIFLTVPSTVPATSAALETAGGDLTPDKIAGLFDRWPEAVALGEKMDFVPVCMGDERSHAILAAALQRGRPVSGHVYGREFVAAYAASGVTDTHEAIDRDIADDLLDAGVWIFLRGGPPTTPWHSLPQAIRTITELGASHKRTAVCTDDRDADDLMLFGLDWVVREAVKAGMSPEQAWSMGSLHGATRFAMDGEIGGLGGGRRADLVLLDDGLKPQSTWYGGELVVDQGKITSLLDQALSQRYQYPKAAYATVKLPAQMKLTPELPAKACTVNAIKTALPGITLIHEKVAIKPANDWDTLFARHGLCFVAVIERHGKSAGNVAHGLLKDFGLKRGAVASSVGHDSHNIIVAGTNEADMQTAVAAIGAQQGGVCVVADGKVRAMVPLPIAGLLSDKRVTAVAEEVKLLKKEWAEAGCTIPYMGFNLIPLSVIPEIRITDKGLVLVPQMELAPLFE
What are the official names of this protein?
Adenine deaminase 2, Adenase 2, Adenine aminase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RSMA_BURM9
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDAIVAAIRPERGERMVEIGPGLGALTGPVIARLATPGSPLHAVELDRDLIGRLEQRFGELLELHAGDALTFDFGSIARPGDEPSLRIIGNLPYNISSPLLFHLMSFAPVVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELPAVDPAVLGEVVTAAFSQRRKMLRNTLGGYRDLVDFDALGFDLARRAEDIGVDEYVRVAQAVASARASG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_ECOLC
Sequence: MNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJM_BACSU
Sequence: MLKKVILAAFILVGSTLGAFSFSSDASAKHVNGNITWYNGVGKKGSSGKKLGHWDCATKIGFDVPRNGTKIRAYAKAKPKKVITVYKNDVGRMPNAVLDVSPKAFKALGYPLSKGKVAGHYSY
What are the official names of this protein?
Uncharacterized protein YdjM, PSPA13.
Protein: NADA_MYCSJ
Sequence: MTLLDETASAQFGDDVAPTEEWAAEVRRLARQRGATLLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPDKTVLIPDARAGCSLADSITADQLREWKAEYPGAVVVSYVNTTAAVKAETDICCTSSNAVDVVASIPADREVLFCPDQFLGAHVRRVTGRTNMQIWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPADRVKILSTGGMLDAARESRASQVLVATEVGMLHQLRRAAPEIDFQAVNDRASCRYMKMITPAALLRCLTYGTDEVDVDHETARLARRSVQRMIEIGQPGGGE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFC_FERPA
Sequence: MKIYVPFKPTNPKSRLSKIMSEDERREFAFQLLLDVLDCCEEAVVLSASRDERLRDLKHEVDERDLDTAVTSRIKKEDSAFVMSDLALISKKIVKKFLDTDGDVVIAPGRKGGTNMLLSRSREFYTSYHYGSFLKHVRIAEKLGLNLSIFDSFYASIDIDDESDLLELMLHGKGKRSYEYLESIGFYVDFSEKEPKLKRA
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: PNGF_ELIMR
Sequence: MRKLLIFSISAYLMAGIVSCKGVDSATPVTEDRLALNAVNAPADNTVNIKTFDKVKNAFGDGLSQSAEGTFTFPADVTTVKTIKMFIKNECPNKTCDEWDRYANVYVKNKTTGEWYEIGRFITPYWVGTEKLPRGLEIDVTDFKSLLSGNTELKIYTETWLAKGREYSVDFDIVYGTPDYKYSAVVPVIQYNKSSIDGVPYGKAHTLGLKKNIQLPTNTEKAYLRTTISGWGHAKPYDAGSRGCAEWCFRTHTIAINNANTFQHQLGALGCSANPINNQSPGNWAPDRAGWCPGMAVPTRIDVLNNSLTGSTFSYEYKFQSWTNNGTNGDAFYAISSFVIAKSNTPISAPVVTN
What is the function of this protein?
Cleaves an entire glycan from a glycoprotein.  Requires that the glycosylated asparagine moiety (reaction 1) be substituted on its amino (R1) and carboxyl (R2) terminus with a polypeptide chain.
What are the official names of this protein?
Peptide-N(4)-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F, PNGase F, Glycopeptide N-glycosidase, N-glycanase.
Protein: PNCB_ERWT9
Sequence: MTRHAAPILTTLLDTDAYKLHMQQAVFHRYYDVTVTAEFRCRGEDMLGIYADELVQQIANMASLTLTDNEFAYLSSLPFFKTDYLNWLRTFRYNPEQVTVQNLQGKLDIRISGPWREVILWEVPLLALISEVVHRHRSPQITPEQAVSRLKSKLEQFKRLTCDLDMSRFRLMDFGTRRRFSHDVQLAVVSTLKQDFPWLVGSSNYDIARRLNIAPVGTQAHEWFQAHQQISPTLENCQRAALQAWLDEYPDRLGIALTDCITTDAFLRDFGSEFAHAYQGLRHDSGDPFEWGEKAIAHYQQLNIDPLSKTLVFSDNLDLDKAVGLYRHFEQRINVIFGIGTRLSCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPRVKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: RS18_CARHZ
Sequence: MKKEKGSRRKKRVCAFCVDKIVDVDYKDVNRLKKYITERGKILPRRISGNCARHQRRLTTAIKRARIMALLPFTVE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RANG_BOVIN
Sequence: MAAAKDTHEDHDTSTENADESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKQELLAIRFLNAENAQKFKTKFEECRKEIEEKEKKGSGKNDSTEKVVEKLEALSVQEGEQPQDAAPAAVEEEQ
What is the function of this protein?
Plays a role in RAN-dependent nucleocytoplasmic transport.  Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity).  Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (By similarity).  Promotes the disassembly of the complex formed by RAN and importin beta.  Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity).  Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN.  Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1.  Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (By similarity).
What are the official names of this protein?
Ran-specific GTPase-activating protein, Ran-binding protein 1, RanBP1.
What is the protein family that this protein belongs to?
Belongs to the RANBP1 family.
Protein: MIAA_CLAM3
Sequence: MIPIVAVVGATGTGKSGLSLDIADRLRAQGRVAEIVNADAMQLYRGMDIGTAKLPEAARRDVPHHMLDVLDVTAEATVAGYQGEARRVITGILGRGAVPILVGGSGLYVSSVLFDYEFPGTDPEIRQRLERELAETGPGMLHRRLRELDPAAAQRIGAHNGRRLVRALEVVEITGPQPERASAEPRPWHPARILALTLPREELVPRLDARVSGMWADGLVDEVAGLLPAGLADGVTASRAIGYAQAARQLAGELTEEEAMEETRALTRRYARRQVSWFGRYADAVRLDARDERLLEHALDALPAARP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GSPG_PECCC
Sequence: MQQSQRGCGQNSYGQSGYRQRGFTLLEIMVVIVILGVLASLVVPNLMGNKEKADRQKAVSDIVSLESALDMYKLDNNRYPSTEQGLKALVTKPTVQPEPRNYPADGYIRRLPQDPWGTDYQLLNPGQHGKLDIFSLGPDGMPGTEDDIGNWNLDKK
What is the function of this protein?
Core component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Pseudopilin (pilin-like) protein that polymerizes to form the pseudopilus.  Further polymerization triggers pseudopilus growth.
What are the official names of this protein?
Type II secretion system core protein G, T2SS core protein G, General secretion pathway protein G, Pectic enzymes secretion protein OutG.
What is the protein family that this protein belongs to?
Belongs to the GSP G family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CMOA_ECOSM
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: NS1_I68A4
Sequence: MDSNTVSSFQVDCFLWHVRKQVVDQELGDAPFLDRLRRDQKSLRGRGSTLGLNIEAATRVGKQIVERILKEESDEALKMTIASAPASRYLTDMTIEELSRDWFMLMPKQKVEGPLCIRIDQAIMDKNIMLKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWGSSNENGRPPLTPKQKRKMARTVRSKVRRDKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: CAH2_CHLRE
Sequence: MARTGALLLAALALAGCAQACIYKFGTSPDSKATHTGDHWDHSLNGENWEGKDGAGNPWVCKTGRKQSPINVPQYHVLDGKGSKIATGLQTQWSYPDLMSNGSSVQVINNGHTIQVQWTYDYAGHATIAIPAMRNQSNRIVDVLEMRPNDASDRVTAVPTQFHFHSTSEHLLAGKIFPLELHIVHKVTDKLEACKGGCFSVTGILFQLDNGPDNELLEPIFANMPTREGTFTNLPAGTTIKLGELLPSDRDYVTYEGSLTTPPCSEGLLWHVMTQPQRISFGQWNRYRLAVGEKECNSTETDAAHADAGHHHHHHRRLLHNHAHLEEVPAATSEPKHYFRRVMEETENPDAYTCTTVAFGQNFRNAQYANGRTIKLARYE
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 2, Carbonate dehydratase 2, CA2.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ASSY_METS5
Sequence: MKIVLAYSGGLDTTVAIKWLSETFHAEVISVSVDVGQKDDFKKIEERAYKAGSAKHYLVDAKREFAENFALKDIKMNGLYEEVYPLATALARPLIAEKVAEVAKKEGTEYVAHGSTSKGNDQVRFDLALKTALDNVKIIAPARIWKMTREDEIAYARERGIPIKTESSKYSIDENLWGRSIEGDIISDPASEVPEDAFEWTAVRKQDKLKLSVEFEKGVPVRVNGEKLDPVKLISLLNEEVGSRGFGRVEHLENRVVGFKSREVYEAPAALALIAAHKDLEKTVLTPLELRFKRHLDSLWSDLVYQGLWYEPLRNTLELAGDEINKWVSGEVKLEVDLKSLRVVGRTSPYSPYSEKISSYNKGWYPSDEEARGFIEIWGMHSLLTRKARYG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIVIB_STRR6
Sequence: MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEVALAEEKEKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEPESKEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKDIRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTKFTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFVSELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKPQLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQTNQRSSRR
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.