PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_PORG3
Sequence: MKIVLLVVGKTDSKLMAQATEEYIRRLSHYVSFEVEVIPDVRLGSKLSSEQQKDAEGREILARLRPSDSTVLLDERGREYSSMEFSAFLQKKMLTGTRRMVFVIGGPYGFSPAVQEAVADRISLSRMTFSHQMIRLFFTEQVYRAMTILNHEPYHHE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI5C_ECOLX
Sequence: MFFKDILISSHTILPSLVRVQNRMLVRIKLFECLIEHILNHVHHWSFRKAVRNNFVVEEIYYWRQIQLAPIDCKFSNIGNPLLVWPRSLEISLENIRGGLPYLSSVRAVSLDLNRCFK
What are the official names of this protein?
Insertion element IS150 uncharacterized 14 kDa protein, ORFC.
Protein: Y016_MYCPN
Sequence: MKHISAVYNPAFTNIASKLNQTELLKDAAQSLNIQLDFFTCFDINTNQDKTKLPFKSNTILFLDKNIALAQWLESVGLRVINSSIAINNADNKALSHAVLAQHPTIKQIPTLIGPQNFRLAWYPEKLEQFIEQIKRCFQFPVIVKSIYGSFGDYVFLCKDEQKLRQTLSGLTEQIIVQQYIATSNSEAVRVIVVNNQVVGALHTQNEGDFRSNLNKGAVGEPYQLSQEETKLAITISQAMQLFYCGIDFLFDQDRSLIFCEVNSNVQLTKSSMYLKTNLAIQLLASIA
What are the official names of this protein?
Uncharacterized protein MG012 homolog.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: IF1C_HORVU
Sequence: MTEKKNRREKKNPREAKVTFEGLVTEALPNGMFRVRLENDTIILGYISGKIRSSSIRILMGDRVKIEVSRYDSSKGRIIYRLPHKDSKRIEDSKDSEDLKDSEDLKDTKDSKD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMG_SHEWM
Sequence: MHFHERFDVIVIGGGHAGTEAALAAARMGSKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDALGGAMAIATDYAGIQFRTLNSSKGPAVRATRAQADRALYRAKIQEILQNQPNLRLFQQAVDDLIVENGRVTGVVTQMGLAFEAPAVVLTAGTFLSGKIHIGMQNYSGGRAGDPPSIALADRLRELPIRIGRLKTGTPPRIDANTINFDLMTEQKGDTPLPVMSFIGDVSQHPKQISCFVTHTNEKTHDIIRGGLDRSPMYSGVIEGVGPRYCPSIEDKIHRFADKSSHQIFIEPEGLNTNEIYPNGISTSLPFDVQLNLVRSIKGMENAEIIRPGYAIEYDYFDPRDLKNSLETKSIDGLFFAGQINGTTGYEEAGAQGLLAGMNASLQVQGKEIWCPRRDEAYLGVLVDDLSTLGTKEPYRMFTSRAEYRLLLREDNADLRLTEKGREIGLVDDERWAKFSEKRESIELELQRLRSQWVHPNSPLIDVLNPELNTPISREASFEDLLRRPEMDYPKLMSLEGFGPGLDDPRAAEQVQIQVKYSGYIQRQQDEIDKAIRHETTGLPLDLDYQEVPGLSNEVIAKLNDHKPETIGQASRISGMTPAAISILLVHLKRRGLLRKKAS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAS1_MOUSE
Sequence: MMAATVVSRIRTGTGRAPVMWLSLSLVAVAAAVATEQQVPLVLWSSDRNLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLKSEDVPYTAALTAVRPSRVARDITMVAGGLGRQLLQTQVASPAIHPPVSYNDTAPRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEPLFGATVTFKFILASRFYPVSARYWFAMERLEIHSNGSVAHFNVSQVTGPSIYSFHCEYVSSVSKKGNLLVTNVPSVWQMTLHNFQIQAFNVTGEQFSYASDCAGFFSPGIWMGLLTTLFMLFIFTYGLHMILSLKTMDRFDDHKGPTITLTQIV
What is the function of this protein?
Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles (PubMed:18713856).  Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity.  Involved in membrane trafficking and Ca(2+)-dependent membrane fusion.  May play a role in the assembly of the V-type ATPase complex.  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).  In islets of Langerhans cells, may regulate the acidification of dense-core secretory granules (PubMed:18713856).
What are the official names of this protein?
V-type proton ATPase subunit S1, V-ATPase subunit S1, Protein C7-1, V-ATPase Ac45 subunit, V-ATPase S1 accessory protein, Vacuolar proton pump subunit S1.
What is the protein family that this protein belongs to?
Belongs to the vacuolar ATPase subunit S1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Note=Not detected in trans-Golgi network.
Protein: PNP_STAES
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDEATLTARLIDRPIRPLFPKGYRHDVQIMNIVLSADPDCSPEMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYVINPSVADKEISRLDLEVAGHKDAVNMVEAGASEITESEMLEAIFFGHEEIKRLVAFQQEIIDHIQPIKQEFVPVERDEDLVEKVKSLTEDKGLKDTVLTFDKQQRDENLDALKEEVVGHFLDEEDPENETLVKEVYAILNDLIKEEVRRLIADEKIRPDGRKVDEIRPLESEVGLLPRAHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEVEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALRYIIPDTQDFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTRDDSYTILTDIQGMEDALGDMDFKVAGTKDGITAIQMDIKIDGLTREVIEEALEQARQGRLAIMDHMLHTIEQPREELSAYAPKVVTMSINPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAKEIIEDITREAEVGQVYHAKVKRIEKYGAFVELFPGKDALLHISQISQERINKVEDVLKIGDTIEVKITEIDKQGRVNASHKVLEQSKN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTA_ECOHS
Sequence: MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAIKTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSQEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRLVRLCAEEKTA
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: PAR1_BOVIN
Sequence: MGPRWLLLWAAGLGLCSPLVSARTRGPRPGTDPTNGTLGPRSFFLRNSNDGYEQIPLPEDEDSSEGEFTEDRLSSGNRSSPPQKSPPGFISKSASGYLTSAWLTVFIPSVYTGVFLVSLPLNIMAVVVFVLKMKVKKPAVVYMLHLAAADVLFVCVLPFKISYYFSGSDWRFGSAMCRFVTAAFYGNMYASIMLMTAISVDRFLAVVYPIQSLSWRTLGRASFICLAIWAMAIAGVAPLLLQEQATQVPGLNITACHDVLNQTLLEGYYSYYFSAFSAVFFFVPLTLSTVSYVSIIRCLSSSTVANQNKKSRALLLSAAVFCIFILCFGPTNILLLLHYAFLSSDPMTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRHLFAILHCKESSDPGSCNSSGQLMPSKMDTCSSNLSSSLYKKLLT
What is the function of this protein?
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
What are the official names of this protein?
Proteinase-activated receptor 1, PAR-1, Thrombin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NVFC_ASPN1
Sequence: MGSLHDYVLIITGSASGIGLATATIALDEGARVLGVDISSPPRSLIDHSNFKFVEGNLSLEPTPRRVVEACVKAFGGRIDGLLNIAGVMDLNQSVDSLSDTMWESCIAINLTAPVKLMREVIPIMRQQKSGSIVNVASKAALSGAVSGVAYTASKHGLVGATKNVAWRFKQENIRCNAVCPGAVDGTSIHRGLETSQFDSEALGTMSLIHEAHMRDRERGIHIQPEDIARSLLFLVSSRSNGINGAIIPIDNAWSTI
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety (PubMed:29968715).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase nvfA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:29968715).  DMOA is then converted to farnesyl-DMOA by the farnesyltransferase nvfB (PubMed:29968715).  Epoxydation by FAD-dependent monooxygenase nvfK, followed by a protonation-initiated cyclization catalyzed by the terpene cyclase nvfL leads to the production of asnavolin H (PubMed:29968715).  The short chain dehydrogenase nvfC then as a 3-OH dehydrogenase of asnovolin H to yield chemesin D (PubMed:29968715).  There are two branches to synthesize asnovolin A from chemesin D (PubMed:29968715).  In one branch, chemesin D undergoes Baeyer-Villiger oxidation by nvfH, methylation by nvfJ, and enoyl reduction by the nvfM D enoylreductase that reduces the double bond between C-5'and C-6', to form respectively asnovolin I, asnovolin K, and asnovolin A (PubMed:29968715).  In the other branch, the methylation precedes the Baeyer-Villiger oxidation and the enoyl reduction to yield asnovolin A via the asnovolin J intermediate (PubMed:29968715).  Asnovolin A is further converted to fumigatonoid A by the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI that catalyzes an endoperoxidation reaction (PubMed:29968715).  The alpha/beta hydrolase nvfD then acts as an epimerase that converts fumigatonoid A to its C-5' epimer, which then undergoes spontaneous or nvfD-catalyzed lactonization (PubMed:29968715).  The following step utilizes the ketoreductase nvfG to produce fumigatonoid B (PubMed:29968715).  The dioxygenase nvfE further converts fumigatonoid B into fumigatonoid C (PubMed:29968715).  Finally the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfF catalyzes two rounds of oxidation to transform fumigatonoid C into the end product, novofumigatonin A (PubMed:29968715).
What are the official names of this protein?
Asnovolin H dehydrogenase nvfC, Novofumigatonin biosynthesis cluster protein C, Short chain dehydrogenase nvfC.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RLMH_SALG2
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_BRUO2
Sequence: MAQRERNREERGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALIVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TPMT_MOUSE
Sequence: MSLDMKEHPDAEVQKNQVLTLEDWKEKWVTRHISFHQEQGHQLLKKHLDTFLKGQSGLRVFFPLCGKAIEMKWFADRGHTVVGVEISEIGIREFFAEQNLSYTEEPLAEIAGAKVFKSSSGSISLYCCSIFDLPRANIGKFDRIWDRGALVAINPGDHDRYADIILSLLRKEFQYLVAVLSYDPTKHAGPPFYVPSAELKRLFGTKCSMQCLEEVDALEERHKAWGLDYLFEKLYLLTEK
What is the function of this protein?
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) using S-adenosyl-L-methionine as the methyl donor (PubMed:18484748).  TPMT activity modulates the cytotoxic effects of thiopurine prodrugs.  A natural substrate for this enzyme has yet to be identified.
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_PSYIN
Sequence: MKDLLKFLKQQNKTKEFDGIKIGLASPEMVRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQSKVRRDRMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERILYFESFVVVEPGMTDLERRQILLEEEYLDMLEQWGDEFEAVMGAEAIFSLLKQLDLDHEIAEMREELGTTNSETKRKKLTKRLKLVESFHQSSNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFVYGKLEALGLATTIKAAKKLVDREGGEVWDILEGVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTIEAQLEARTLMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRSKINSLGEDMWFQSAKEAEKAYRAGAVGLQAIVKVRMKQVHIADDKSRTETTNIIETTVGRAILSLIMPEGLPFELVDLPMGKKQISTALNACYRLLGIKHTVIFADQLMYTGFEYATLSGASVCIDDMVIPTTKKTLVEAAEAEVQEIHEQFQAGLVTAGERYNKVIDIWASANEQVAKAMMENLSKDTVVNSKGEEVQQDSFNSVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDIAQDLVITEKDCGSEDGLLVTPLIQGGDVVEALRERVLGRVVAQDIIKPGTKGEVLIARNVLLDEKLCDLIEEASVDQVWVRSVITCQTDFGACAQCYGRDLARGHMVGQGEAIGVMAAQSIGEPGTQLTMRTFHIGGAASRAASENNIQVKNTGKIKLHNAKFVINSEQKVVVTSRSTELTIIDKLGRTKENHRLPYGAVLEKQDGAEITSGEIIANWDPHTHPIITEVEGTVQFLDFIEGLSITKQADEFTGLSSTVIIDPAQRPNAGKELRPMVKLVDPQGNDLFIPGTDVAAQYALAANAIVSLEDGAKVRVGDAVARIPQESSKTRDITGGLPRVADLFEARTPKDAAILAEVSGTLAFGKETKGKRRLVITQANGEAYEEMVPKWRHLNIFEGEKIEKGEVISDGPESPHDILRLRGISPVANYITNEVQEVYRLQGVKINDKHIEVIVNQMLRKGTITDNGDSAFLVGEQAEVARVVIENRRLVAEGKAIATFDYQLLGITKASLATESFISAASFQETTRVLTEAAVAGKCDQLHGLKENVIVGRLIPAGTGFAHHRARAAAKAAELAPKVEETIVDTGTAEQNLADLLNAVDFGD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MYSN_ACACA
Sequence: MAAQRRRKGGEVESDYIKYLKYKNTGFQVSASDKTLAWWPTKDADRAFCHVEVTKDDGKNFTVRLENGEEKSQPKNEKNFLGVNPPKFDGVEDMGELGYLNEPAVLHNLKKRYDADLFHTYSGLFLVVVNPYKRLPVYTPEIIDIYRGRQRDKVAPHIFAISDAAYRAMLNTRQNQSMLITGESGAGKTENTKKVIQYLTAIAGRAEGGLLEQQLLEFNPILEAFGNAKTTKNNNSSRFGKFIELQFNAGGQITGANTFIYLLEKSRVTAQGAGERNFHIFYQILSKAMPEELKQKLKLTKPEDYFFLNQNACYTVDDMDDAKEFDHMLKAFDILNINEEERLAIFQTISAILHLGNLPFIDVNSETAGLKDEVELNIAAELLGVSAAGLKAGLLSPRIKAGNEWVTRALNKPKAMASRDALCKALFGRLFLWIVQKINRILSHKDKTALWIGVLDISGFEIFQHNSFEQLCINYTNEKLQQFFNHHMFTLEQQEYEREKIDWTFVDYGMDSQDCIDLIEKKPMGILPLLDEQTVFPDADDTSFTKKLFQTHENHRNFRRPRFDANNFKIVHYAGEVEYQTSAWLEKNRDPLEDDLSNLCKKSSVRFVTGLFDEDLMPSFKAAPAEEEKAAAGGSRNRSTGRGKGGAQFITVAFQYKEQLAHLMSMLSSTAPHFIRCIIPNLGKKPGVVSDQLVLDQLKCNGVLEGIRIARKGWPNRLKYDEFLKRYFLLKPGATPTSPSTKDAVKDLIEHLIAKEPTKVNKDEVRFGVTKIFFRSGQLAAIEELREQAISKMVVSIQAGARAFLARRMYDKMREQTVSAKILQRNIRAWLELKNWAWYQLYVKARPLISQRNFQKEIDDLKKQVKDLEKELAALKDANAKLDKEKQLAEEDADKLEKDLAALKLKILDLEGEKADLEEDNALLQKKVAGLEEELQEETSASNDILEQKRKLEAEKGELKASLEEEERNRKALQEAKTKVESERNELQDKYEDEAAAHDSLKKKEEDLSRELRETKDALADAENISETLRSKLKNTERGADDVRNELDDVTATKLQLEKTKKSLEEELAQTRAQLEEEKSGKEAASSKAKQLGQQLEDARSEVDSLKSKLSAAEKSLKTAKDQNRDLDEQLEDERTVRANVDKQKKALEAKLTELEDQVTALDGQKNAAAAQAKTLKTQVDETKRRLEEAEASAARLEKERKNALDEVAQLTADLDAERDSGAQQRRKLNTRISELQSELENAPKTGGASSEEVKRLEGELERLEEELLTAQEARAAAEKNLDKANLELEELRQEADDAARDNDKLVKDNRKLKADLDEARIQLEEEQDAKSHADSSSRRLLAEIEELKKRVAKETSDKQKAQDQKANYQRENESLKADRDSIERRNRDAERQVRDLRAQLDDALSRLDSEKRAKEKSVEANRELKKVVLDRERQSLESLSKFNSALESDKQILEDEIGDLHEKNKQLQAKIAQLQDEIDGTPSSRGGSTRGASARGASVRAGSARAEE
What is the function of this protein?
Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
What are the official names of this protein?
Myosin-2 heavy chain, non muscle, Myosin II heavy chain, non muscle.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: SKB15_SCHPO
Sequence: MLRFVVGTYTHLIYGVDADIERKKCKPLWLFEAHEGALTALAVDGIYLASTSSDETIKIFDHTRNVQIADVSVPTDIANACIRDMCFTKNHLLACHDNGQISMWSKGSWLLVHTLKSSSHKGITGIAVHPSEKLALTVGGDGKLRLWDLVRGKGGKVLPLSTIPESILFLNESSFVIMSRRGIDAFKLDLTSLFSFSSKSQLNALCLYQSKLIVGRDNGTVLVLDTSDGKILHEFTAHKKRVKSVYPVDDYLITASSDGSVCIWDKDWNLVIEHNIPEGNRITCMVAMLADSNSEPKNVEDEAAKRQSLDSETSETSSESESESEYYSTSKQPPVKRTKHA
What is the function of this protein?
Interacts with pak1/shk1.
What are the official names of this protein?
Shk1 kinase-binding protein 15.
Protein: RBN_SALG2
Sequence: MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQHQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIATTLRLSGSWTDFPLQIEEVSAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALNARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEAALALAQGVDVMVHETTLDASMEEKANSRGHSSTRQTATLAREAAVGRLIMTHISSRYDDKGCQRLLAECRAIFPATELAYDFSVFPV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: NADA_CLOP1
Sequence: MDIRNEILKLKKEKGAIILAHYYQIPEIQEIADYVGDSYYLSKIAKDCEENIIVFCGVKFMAESAKILSPEKTVILPVMEAGCVMADMATADGLAKLKEEHPNAKVVCYINSSTEVKALSDVCCTSSNAENIINNLEEKEIIFLPDRNLGSYIQEKTPDKKFILWNGFCIVHEAIQKEEILRLKSEHEGILTVAHPECSKEIRDISDFIGSTSEIINFVNNSSNKKFIIITEEGVLHQLRKNGEEKEFYIPYGKMVCRNMKMTTLKDLYESLLKMENKIEIDEDLRLKAYNSLKNMHKLGG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SETD3_DROME
Sequence: MGKNTKRNKKTKQQQQQPQQNGVTASASGTAVEDFEDQQAASSLPSLNGKKRSQLNKLVEELLDLVEKQPANPNEEWKQYGQLQELLKQIMILEEPLSQAVCPQISDSPDDQTRLAKVEAFSAWAKDGGVHSEGLEIAIFPGYQLGLRATRPLAKDELVLSVPRKLILSEENNSDCRLFGKMTQATHLNLAYDLVIEKIRGEFSEWRPYIDVLPAKYNTVLYFTTKQMELLRGTAAAALAMRQCRVIAKQYAFLYKYAHTMTEPSTGNRSHPGERGLFFTQHGLCYKLYRWAVSTVMTRQNLVPSEKQESEDGPKLISALIPYWDMANHRPGKITSFYATVSRQLECTAQEAVNTGEQFFIYYGDRSNTDLLVHNGFVDPNNTKDYVNIRVGLSLTDALAAKRASILDKLNIRHTAELRVLPAPDFISKELLAFVRVFKMSAEQLDHWCSDLDRAGDLLHIDCALETDHETRTWQFLEDRLKLLLAVFNKEMHEADEVKELELKDGQEIELMLFLYRRLERSILAGALQYAQEHRKV
What is the function of this protein?
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-74'.
What are the official names of this protein?
Actin-histidine N-methyltransferase, Protein-L-histidine N-tele-methyltransferase, SET domain-containing protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the cytoplasm.
Protein: GLPE_PSEPW
Sequence: MSEFKRIPPEQALALRAQGAVVVDIRDPQAYAAGHIAGARHLDNHSVADFIRNADLDAPTLVVCYHGNSSQSAAAYLVGQGFSDVYSVDGGFELWRSTYPDETAQGTPE
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYTR_STAAM
Sequence: MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNNASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism.  Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs).  Upon phosphorylation by LytS, functions as a transcription regulator by direct binding to promoter regions of target genes including lrgA and lrgB, to positively regulate their expression.
What are the official names of this protein?
Transcriptional regulatory protein LytR, Sensory transduction protein LytR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_MYCPN
Sequence: MKRCYITTPIYYASGKPHIGHAFTTILADVIKRYKQQNGYEAYFLTGTDEHGNKIESKAKSLGLDPQTFVDQNVAYFQQMWKQLDINFDHFIRTTDLSHKAQVQHAFQLLYDKGLIYQSNWEGAYCVECEQNYFTYDKQTMLCEIGHQLTLVQEPSLFIAFKDSKDWIGEMIATNKLNITPESRAAELKNNFLDGGLNDLALTRQNVTWGIPVPFDNKQTIYVWFDALFNYITNLGFAHNDPKFNKWWNNNDEEHEVIHLISREITRFHCIYWPIFLHQLGFKLPTQFLSHGWIVDGNGHKMSKSLGNVISPEELLAQFGVDGTRYCLLKEMRLDKDNRCSMAIFKDIYNADLANSFGNHASRTFGMIKKYLGGQLDFIEVQDPQVKQLMDQANQAMVQFDTAWNNFQFYKGINGLLQLVFQASKLIDQLKPWELVKQTDYTLLKQLLFACVRCTQVCFVLLAPILVHTSTQIFDLFNFSAQARSKTHLADPQQLQKISLAPVIQPLFKRLD
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.