PharMolix/UniProtQA huggingface dataset:
Protein: NAD1_CAEEL
Sequence: MARKRGISSLLLIYKQSFVIWGALLIFSPLLMFVGDSHGLQAKCLYCVAVMGSYWVFEALPLAITAFIPMILFPLFGIMRSEEVARAYLPDTCFLFMGGLMVALAVEKCELHARVALFVLKTVGSEPARVMAGFMGVTGFLSMWISNTATTALMVPILQSVITELVSNHRMEDLVALCEAHHNSSRKHSVGMRRLSLPNENNEIKREEMDTAMSPREQKMAKGLMLSVCFSANIGGAATITGTASNLVLVGQLNELFPGADTGVNFLSWLIFAFPMVFCCLIYCWCVLYLLYLRDAPKGSIIVTRKLQQKYNELHAFSFAEMAVIFCFALLLVLWILREPQVVPGWGEMFKDEFVSDATSAMFIVILLFTLPEKLPSSRGSSEQRKASSGLLDWATVQDRFPWSVLFLLGGGFALAAGVKESGLSHDIGAIMRYLDVFNHNIIMLICIIISVTLTNVCSNTVIASIFIPIVAELARSLEIDPLNFMLPVTISASFAFLLPVATPPNAIVFSSGYLKVFDMFVSGLCVTLGCVVLSMLNMLLWAGFVFNLHLFPQWAANPSPPLDVQDWAVENNITFVGTSKL
What is the function of this protein?
Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms.  There is no interaction with monocarboxylates.
What are the official names of this protein?
Sodium-dependent low-affinity dicarboxylate transporter 1, Na(+)/dicarboxylate cotransporter 1, NaDC-1, ceNaDC1.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: THOC7_NEMVE
Sequence: MADDEVIRKRLLIDGEGVGDDRRITTLMKTFVKWCNSTDDDNDASYQKLLAQLAQCEFAMGKTEMVHAMNERETENYEKAYKEVEQSITHAYEEIATCKTNLQEAKRIRRNKQEYDALAKEITKHPERQETTRQISELEKDLNSLTETKESLVSKLELRKKQFYLLINTIHELQRMIDDEKTDEGTALSPQQSITSPGKVALMDT
What is the function of this protein?
May act as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.
What are the official names of this protein?
THO complex subunit 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle.
Protein: CYSK_STAHA
Sequence: ELTTGPEIVEQFEGKQIDAFLAGVGTGGTLSGAGKVLKEKYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFVPDTLNTDIYDSIIQVGNDIAMETSRRVAKEEGILAGISSGAAIHAAIQKAKELGKGKTVLTVLPSNGERYLSTPLYSFDD
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: RBBP4_BOVIN
Sequence: MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
What is the function of this protein?
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.  These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
What are the official names of this protein?
Histone-binding protein RBBP4, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Note=Localizes to chromatin as part of the PRC2 complex.
Protein: SDHF3_RAT
Sequence: MTGRHVSRVRSLYRRILQLHRALPPDLKALGDQYVKDEFRRHKTVGPGEAQRFLKEWETYAAVLWQQAKDSRQSSSGKACFGTSLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSITESTKPHL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit Sdhb of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3, Liver regeneration-related protein LRRGT00092.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PYRG_METNO
Sequence: MTRYVFITGGVVSSLGKGLASAALAALLQARGYRVRLRKLDPYLNVDPGTMSPTQHGEVFVTDDGAETDLDLGHYERFTGVPATRADNITTGRIYLDIITKERRGDYLGATIQVIPHVTNAIKEFVLDGNEGYDFVLVEIGGTVGDIEGLPFFEAIRQLGQELPRGQCAYIHLTLLPYIPSAGELKTKPTQHSVAELRSIGIQPDILLCRCDRPIPREERRKLAQFCNVRESAVIEARDVASIYDVPLSYGEEGLDREVLALFGIEATSEPKLDRWRTISERVKNPEGEVSIAIVGKYTGLKDAYKSLIEALTHGGIANRVKVNLEWIEAEIFEREDPAPFLEGLNGILVPGGFGQRGAEGKIRAARYAREKKIPYFGICFGMQMAVVEAARSLAGIPEANSTEFGPTPEPVVGLLTEWMRGNELERRVAEGDLGGTMRLGSYTAKLAPDSRIAEIYGGTAIAERHRHRYEVNMAYRERLEARGMRFSGLSPDGLLPETVEVEGHPWFIGVQFHPELKSRPFEPHPLFKSFIGAAVVQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RUVC_PETMO
Sequence: MVILGIDPGYGRIGYGVLEKKGNMFNLIDYGVIYTSKEDELPKRLLNIDEQLRNLIETYKPDESAVEKLYFFKNVATAIQVGEARGVILLCLEKENIPIYEYTPFQIKQAVTGYGRAEKGQIQRTLKLLLKLEKTPTPDDAADALATAFCHGNFRRSFKNAGY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ARLY_CALS4
Sequence: MKLWGGRFKKDLDKLMEDFNSSISFDIRLLKYDIMGSIAHAKGLYKAGVLTEEELNLIEKGLKEILEESELKEIPQDEDVHSYVERLLVEKIGDVGRKLHTGRSRNDQVATDERLYLRDEIDKIKEDLIKLIDTLKEMAETYKETIMPGYTHLQRAQPVTFGHYLLAYVEMFKRDLSRLDDMMKRVNVMPLGSGALAGTTFNIDRYYVASLLGFDDITLNSMDGVSDRDFVIEFLSFASITMMHLSRFCEELILWSTKEFDFIEMDDRFSTGSSMMPQKKNPDAAELIRGKTGRVYGDLITILTVMKGLPLAYNKDMQEDKEALFDGIDTLKMSLKVFTEMIKTIKVKTDNMEKAAKYGYMNATDFADYLVQKGIPFRTAHEIAGKVVLYAIERNLPIEELSLEELKKFSDVIEKDVYEAIDIKNILKKRKTIGSPRIF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKB2_CAEEL
Sequence: MTAIEKFFTEKSPDSEQVLLKVIELGIDFLGGEWKNVDKSQVNVSRVHGGQSNHMFHVTSSTSATPYLLRIHRQPPSQVFTDTVNLAIFSERGLGPKLYGFFEGGRMEEFLPSKTFDVNDVLVPENSRKIGAIFPLYHSINVPVSKSRRCVHLMREWLNGYESLGGGDYEILPTTVNYSDHPKSVSIKDLNHEIDNFEKWSTEIFEHTLVFSHNDLASTNILELNSTKELVLIDWEFGTYNWRGFDLAMHLSETAIDYRVPFPPGIKMNGDLIDNPPNIQIFCEAYVEADKKLKNRSPSDPTAEVKALIQECQFFWPLTNLFWALSAMKHSLLKFENGVDLDVQARDRLAVYFHLKPRSQKIYEELSKK
What is the function of this protein?
Catalyzes the first step in phosphatidylcholine biosynthesis.  Phosphorylates choline.
What are the official names of this protein?
Choline kinase B2.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
Protein: GPCP1_CAEEL
Sequence: MDQDYKAHFKVFCSEVREWEKIHVVGSLPVLGEWNPRKSFPLTKSTDEENTFHAIVSVPSSIKEFNFRYIRVMYLDPSENNTSEPIMVLSKWETFNNARTCLIGVESQDGVARKNITDQFGSYSGKTQITDGWILNEKESVVYFRIHGEALKFFAKSYANKEYRLKVEPFDVRYSEMFSYTRKDITDRRGVWRHSSVYASMSIDGDDVVNLPTPSLPCFSNTDLSVLTREDPIFGDQYFNGSVFRNDQDYLVFRTRTVSLQNLAFRIEFYHGEKRCALSYVLPSSMSGTHGATVSPVIGLSSAPVGHINVNYMIVKRNKYTDQNLDIDSMKTTFGRYWRKRNRMLQIGHRGMGSSYTKNIGQRENTIFSLNEAARRGADYVEMDVQLTKDLKTVVYHDFHVLVAVAGRDSPSSTPTAAGENKSLHEIAIKDLTLAQLNLLHFEHISRANGSSAESPVALSVTPSKTETDELHVPFPSLAQVLRHVDENVGLNIEIKYPMYMQDGSHECQGYFEQNKFVDIILAEVAEHAGNRRIIFSCFEPDICTMITKKQHKYPVSFLVVGATNRYMPFQDIRSDCSKIAANFAAGCELLGVNFHSEELLIDQKPIEIAEKYGLIKFVWGDDLNSKEVQKHFRDEMNVDGLIFDRIGEDEVLKQNVFVVENHNRSSLFARSQHNSRSPSMSRRCMSTVE
What are the official names of this protein?
Putative glycerophosphocholine phosphodiesterase GPCPD1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: BPP2_GLOHA
Sequence: QGRPPRPHIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent.
What are the official names of this protein?
Bradykinin-potentiating peptide 2, AHBPP-2, Angiotensin-converting enzyme inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: REPA_PASVK
Sequence: MSTVGSSSEGRHSVRCFRHRNANTFLTYSKCPLEPEFIGEHLFRLTREYEPAYILVVRETHTDGTWHCHALLQCIKPCTTRDERYFDIDRYHGNIQSAKSTDKVREYILKDPKDKWEKGTYIPRKKSFVPPGKEPAEKKPTKDEVMREIMTHATSREEYLSLVQSSLPYDWATKLNYFEYSASRLFPDIAEPYTNPHPTTEYDLHCNETIEDWLKPNIYQVSPQAYKLLEPSCLSLEQAIADLEWLDDTTRMLQEKEREASTSAAQHGQVKHPGLEASDDTTTGKTISTGLHMMKKLSTMSLTTFPSSSVRAGNDSSAAKKTT
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: NS5_LDCPR
Sequence: MEAFLLENRKPQITTLASGKTLKPATHRLNLPAYTKLIHELRTKTHAKVAISLSTDSQIHMVWVKSGLVFFTPSASHPAYVNFASSNRLTDVPALTKTTFPQSDVKLIETTPLPNDETSHVASFQLVTWMEGALNILNDLSKCAISFINQCEDTFKSGTNLNKELYNRCITAESRDFCNQMKFVLIGRLCYGQTTSPPPIQLYQYGVTPFISSDIICEGAAYRPIDVENYAMNSNHTVSYAPFFVPNETKPGSRIDLIMVNHLKKFNLMFDSWYKTGGSVMVSSRPERTQNEASVSQIMPTSVKHIANEDLTADDGEGSE
What are the official names of this protein?
Non-structural protein 5, NS5.
Protein: BCE1_HUMAN
Sequence: MGRTPTAVQVKSFTKQGQQRRVCRDLPLKNTKNGLSPGMRTCFLYLRFFPCLSWMSLKWTQAVHCARNIVLSFMLLLLLLNYNM
What are the official names of this protein?
Putative protein BCE-1.
Protein: TOPON_MYCS2
Sequence: MSDPASTIPPAHHPTFWRERAVSYTAADITELDDVQHTRLRPAVNLGLDVLNTALREIVDNAIEEVADPGHGGSTVTITLHADGSVSVADDGRGLPVDTDPTTGKNGIVKTLGTARAGGKFSAHKDATSTGAGLNGIGAAAAVFISARTDVTVRRDGKTFLQSFGRGYPGVFEGKEFDPEAPFTRNDTQKLRGVSNRKPDLHGTEVRILFDPAIAPDSTLDIGEVLLRAHAAARMSPGVHLVVVDEGWPGEEVPPAVLEPFSGPWGTDTLLDLMCTAAGTPLPEVRAVVEGRGEYTTGRGPTPFRWSLTAGPAEPATVAAFCNTVRTPGGGSHLTAAIKGLSEALAERASRMRDLGLAKNEEGPEPQDFAAVTALAVDTRAPDVAWDSQAKTAVSSRSLNLAMAPDVARSVTIWAANPANADTVTLWSKLALESARARRSAEGAKARARAASKAKGLGTNLSLPPKLLPSRESGRGSGAELFLCEGDSALGTIKAARDATFQAAFPLKGKPPNVYGFPLNKARAKDEFDAIERILGCGVRDHCDPELCRYDRILFASDADPDGGNINSSLISMFLDFYRPLVEAGMVYVTMPPLFVVKAGDERIYCQDESERDAAVAQLKASSNRRVEVQRNKGLGEMDADDFWNTVLDPQRRTVIRVRPDESEKKLHHTLFGGPPEGRRTWMADVAARVDTSALDLT
What is the function of this protein?
Catalyzes the relaxation of negatively supercoiled DNA in the presence of ATP or dATP but not other nucleotides.  Individual subunits have no activity.  Not able to negatively supercoil DNA, it can however introduce positive supercoils in DNA.  Relaxes positive supercoils in an ATP-dependent manner.  Catenates and decatenates DNA.  Generates dsDNA breaks in the presence of the quinolone antibiotic ciprofloxacin, showing it is a topoisomerase.
What are the official names of this protein?
Topoisomerase subunit TopoN, DNA gyrase subunit B-like protein MSMEG_0457/MSMEI_0444.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
Protein: PEPT_ECOLI
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKKIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAQRK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_STRA1
Sequence: MLYQQIASNKRKTVVLLIVFFCLLAAIGAAVGYLVLGSYQFGLVLALIIGVIYAVSMIFQSTNVVMSMNNAREVTEDEAPNYFHIVEDMAMIAQIPMPRVFIVEDDSLNAFATGSKPENAAVAATTGLLAVMNREELEGVIGHEVSHIRNYDIRISTIAVALASAVTLISSIGSRMLFYGGGRRRDDDREDGGNILVLIFSILSLILAPLAASLVQLAISRQREYLADASSVELTRNPQGMISALEKLDRSEPMGHPVDDASAALYINDPTKKEGLKSLFYTHPPIADRIERLRHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_STRM5
Sequence: MRVLGIESSCDETGVAVYDTDLAGSAALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLVRQTLAEAGLGVGDIDGVAYTAGPGLVGALLVGAGVARSLAWALEVPAVGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVAVDAIGQYRLLGETLDDAAGEAFDKTAKMMGLPYPGGPQLARLAEQGTPGVYRFARPMIDRPGLDFSFSGLKTQVLMAWRDSDQSEQTRADIARGFEDAVVETLSIKCERALEAAGTNVIVVAGGVGANKRLRARLQQMAERLGGRACFPRPALCTDNGAMIAFAGALRLQAGQHSPPKVDVTPRWDMATLPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CAMJD
Sequence: MDRIVEIEKYSLDETYETSLRPSNFDGYIGQESIKKNLNIFITAAKKRNECLDHILFSGPAGLGKTTLANIISYEMDANIKTTAAPMIEKSGDLAAILTNLSEGDILFIDEIHRLSPAIEEVLYPAMEDYRLDIIIGSGPAAQTIKIDLPKFTLIGATTRAGMLSNPLRDRFGMQFRLEFYKDSELALILQKAALKLNKTCEEKAALEIAKRSRSTPRIALRLLKRVRDFADVNDEEIITEKRANEALNSLGVNELGFDAMDLRYLELLTAAKQKPIGLASIAAALSEDENTIEDVIEPYLLANGYIERTAKGRIASTKSYSALKLNYEKTLFEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: UP355_STAAS
Sequence: MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
What are the official names of this protein?
UPF0355 protein SAS0363.
What is the protein family that this protein belongs to?
Belongs to the UPF0355 family.
Protein: CH10_SHEHH
Sequence: MNIRPLHDRVIVKRSEVESKSAGGIVLTGSAAEQSSRGEVLAVGNGRILENGNVMPLDVKVGDIVIFNEGYGVKKEKIDGEEVLILSESDLMAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_NANEQ
Sequence: MRYSVSLENVAKLYAHNLPISTKHAVEIAKMIRYLPLQLAKEMLQKVLDKELAVPFFRYNRDIPHRKKGQIHPYFKIKHGRFPENATKWILKELNSVEKNAINLGMDPNKLFIVHIAAHKGVRGYTSVYGRRARRKATHLEIMVAENKDYDPSKKYPLKELKRMGHKLFLSLKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GGGPS_SULIM
Sequence: MKIRKKKMKLKGKVKKYLMDKLNDNEKLHFSLLDPFKINSSEELKYIAKNLYNVGTDAFLIGGTLGVSKDKLDFVISLLDDYEIPKIIFPSNINLLSEKADALLFLSLLNSDDIYYVIGAQIVAAPIIKMLQIEVIPTAYVIVGHGGTAAHIGKARVIPYDNFELATAYTLAAEYLGMDFVYLEAGSGAPEPIRPEMISFIKKASSIPLIIGGGIRSVEVALKLVEAGANIIVTGNIIERDVDKAIKIIRGIKNK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_CAPBU
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GRA4_TOXGO
Sequence: MQGTWFSLFVVVMVSHLACGGECSFGSHLADMAGLSGRHDKERHQAKKRYYHSMYGNQTPYPYANGQQASPPPQGQLLIIQNPDGSFMIVDQQGVPQVPQAAGGPGSPMNGGYYMPTGVYTAQVVPGTPGHPVQAIPQQPLRTQATATYYHPAAVPPPGPSVFVFTPSSVQPGAEVTPGYSGLQLRQQSQYGYSYPGTTSTPTPPPPASYGYPVFPAFPRLPAFSDSVSVSTEDSGLTGVKDSSSSESTVTPADEAASESEEGDKTSRKSKVKKGILTGLGVAATLAAAAAAAKAVKGFGGTRTSTAPAEAGKTELDDGYRPPPFNPRPSPYAELLKDLERMRKE
What is the function of this protein?
Major granular component involved in excreted-secreted antigen (ESA) immunity.
What are the official names of this protein?
Dense granule protein 4, Protein GRA 4, Antigen H11.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole lumen. Parasitophorous vacuole membrane. Cytoplasmic vesicle, secretory vesicle. Note=Located in dense granules of tachyzoites. Upon infection, secreted into the parasitophorous vacuole (PV) and targeted to the microvillus membranous network.
Protein: ATPI_PEA
Sequence: MNVLLCYINTLNRFYDISAVEVGQHFYWQIGDFQVHAQVLITSWVVIAILLISTILVVRNPQTIPTSGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIKLPHGELAAPTNDINTTVALALLTSVAYFYAGISKKGLAYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LBD29_ARATH
Sequence: MTSSSSSSGSPCGACKFLRRKCAKGCVFAPYFCHEQGASHFAAIHKVFGASNASKLLSHLPISDRCEAAITISYEAQARLQDPIYGCVSHIFALQQQVVNLQAELEILKQQAAQSMIFADSPTSENPNSYYGDTTKAPYHHDHQNIYHHHDQTHLVYQTGSSGTVQHGDATESSYHNETSSGMGEFSIYSDLEQHLNTFNQDHLKELQSANFGYISFS
What is the function of this protein?
Involved in lateral root formation.  Regulated by the transcriptional activators ARF7 and ARF19.
What are the official names of this protein?
LOB domain-containing protein 29, ASYMMETRIC LEAVES 2-like protein 16, AS2-like protein 16.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: LPTC_HAEIN
Sequence: MIEIKMNIRWNVILGVIALCALAWFYSLNQETADLSELVKKPDSPDYVGYKMETTVFSPDGKKQYLALSDKIEHYTVNEQTLFTAPLVYLYPTTSNEKEKEKNANQNVDFFSTQSWKLSANQARLTKDQILYLEGNVVAQNLTSDSRLQRIETESAVVNLKTQDITSETQVKIKGKNFSSTGLKLVGNLRQQVATLKEQVKTYYEVSKQ
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).  Required for the translocation of LPS from the inner membrane to the outer membrane.  Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA.  Could be a docking site for LptA.
What are the official names of this protein?
Lipopolysaccharide export system protein LptC.
What is the protein family that this protein belongs to?
Belongs to the LptC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.