PharMolix/UniProtQA huggingface dataset:
Protein: CSLC2_ORYSI
Sequence: MAPPGVGVGVAYLWGKGRGGRKGTPVVVTMESPNYSVVEVDGPDAEAELRTAAVAMDKGGGRGRSRSRTARQLTWVLLLRARRAAGRLASFAAAAARRFRRSPADAADELGRGRGRLMYGFIRGFLALSLLALAVELAAYWNGWRLRRPELHVPEAVEIEGWAHSAYISWMSFRADYIRRPIEFLSKACILLFVIQSMDRLVLCLGCFWIKLRKIKPRIEGDPFREGSGYQHPMVLVQIPMCNEKEVYEQSISAACQLDWPREKFLIQVLDDSSDESIQLLIKAEVSKWSHQGVNIVYRHRVLRTGYKAGNLKSAMSCDYVKDYEFVAIFDADFQPTPDFLKKTIPHFEGNPELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGVFLNFFGFNGTAGVWRIQALEESGGWLERTTVEDMDIAVRAHLNGWKFIFLNDVKVLCELPESYEAYRKQQHRWHSGPMHLFWLCLPDILTAKISSWKKANLILLFFLLRKLILPFYSFTLFCVILPLTMFVPEAELPVWVICYVPVCMSFLNILPSPRSFPFIVPYLLFENTMSVTKFNAMVSGLFKLGSSYEWIVTKKSGRSSESDLSTAVERDTKDLTLPRLQKQISESELIDLKMQKERQEKAPLGAKKANKIYKKELALSLLLLTAATRSLLSAQGIHFYFLLFQGVSFLFVGLDLIGEQID
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose (By similarity).
What are the official names of this protein?
Probable xyloglucan glycosyltransferase 2, Cellulose synthase-like protein C2, OsCslC2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: Y056_HAEIN
Sequence: MFEWIADPEAWISLVTLAALEIVLGIDNIIFINILVGRLPERQRQSGRILGLALAMLTRILLLMSLAWIMKLTAPLFTVFNQEISGRDLILLIGGLFLIIKSSGEIKEAINHQEHHESESKNKVSYLGVLIQIAVLDIVFSLDSVITAVGMASHLPVMILAIMIAVGVMMFAAKPIGDFVDTHPTLKILALAFLVLVGISLIAESLDIHIPKGYIYFAMGFSVVVEMINIRMRRLMK
What are the official names of this protein?
UPF0053 protein HI_0056.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFB_STAS1
Sequence: MFISKEWLESYVEINEQVNVLAERITRTGIEVDDIIDYTKEIKNLVVGYVQSIAAHPDADKLNICQVDIGEAEPVQIVCGAPNVDAGQTVIVASVGGRLPGGVKIKRAKLRGEHSEGMICSLQEVGVPSNLVPKQFEDGIFVFSTEVKPGTDALDALYLNDQVMEFDLTPNRADALSMIGTAYETAALYNVPMTKPETQSTETSDQTNDEISVNIQNEDKVPYYSARVVKNVTIAPSPEWMQMRLIKAGIRPINNVVDISNYVLIEYGQPLHMFDQDQIGSKHIEVRQAKADEEMTTLDNQERQLKENDIVITNGETPIAIAGVMGGDFSEVTEATKHVVIEGAIFDPVSIRHTSRRLNLRSEASSRFEKGIATEFVDEAVDRACYLLQTYAGGSVAQGRVSQGELGCFVTPIDISVSKVNQTIGFELSAEDIESIFVQLGFETTKNKDVLTVMVPSRRKDISIKEDLIEEIARIYGYDKIPSTLPVFDQVTHGALTDRQSKSRIIKATLEGAGLNQAINYSLVDKDRAKDFALQERETIDLLMPMSEAHSTLRQSLIPHLIDAVAYNVARKNSDVRLYELGSVFFANGEDELPDEVEYLSGILTGDYTVNHWQSKKETIDFFVAKGIVDRIAEKLDIQFEYEAGEINGLHPGRTAYVELNGEIVGFVGELHPKTEKDYDLKRTYVFELNFDKLMSVSVGYINYQAIPRFPGVSRDIALVVNRATPSAKLVNIIHEHGGNILQEAEVFDVYEGEHMAEDEKSIAIRLAYLDTEQTLTDDKVNAVHEAILEALKSEGATIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_STAA9
Sequence: MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQGYARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQNRLDQEDLKFHEKVIEGYQEIIHNESQRFKSVNADQPLENVVEDTYQTIIKYLEKI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MEG2_MAIZE
Sequence: MEYRKRVDALVFFSLLLLGYFAAHAHGKGHVTDDVGVSTPAKEGIMQGNGARCVVGFPPCKDNKCYCCIGGRTHARYSTMAECRHACF
What are the official names of this protein?
Protein MATERNALLY EXPRESSED GENE 2.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: XYL1_CANTE
Sequence: MSASIPDIKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKEDFEEIAKLDIGLRFNDPWDWDNIPIFV
What is the function of this protein?
Reduces D-xylose into xylitol.  Has a preference for NADPH, but can also utilize NADH as cosubstrate.
What are the official names of this protein?
NAD(P)H-dependent D-xylose reductase, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: PYRD1_BOVIN
Sequence: MEAPCSPPTAGKFVVVGGGIAGVTCAEQLAINFPSEDILLITASPVIKAVTNFKQVSKVLEEFDVEEQPSTMLENRFPNIKVIESGVKQLKSKEHCVLTEDGNQHIYKKLCLCAGAKPKLICEGNPYVLGIRDTDSAQEFQKQLTKAKRIMIIGNGGIALELVYEIEGCEVIWVIKDKAIGNTFFDAGAAEFLTSKLIDEKPEAKIAQKRTRYTTEGRKKETQARASAGNVGSALGPDWHEGLDLKGTKEFSHKIHIETMCEVKKIYLQEEFRISEKKSLTFPRDHHDQSVTTDKEIWPVYVELTNEKIYGCDFIVSATGVTPNTEPFLCGNNFDVGEDGGLKVDDHMHTSLPDIYAAGDICTAAWHPSPVWQQMRLWTQARQMGWYAAKCMAAASVGESIDMDFSFELFAHVTKFFNYKVVLLGKYNAQGLGSNHELLLRCTKGQEYIKAVLQNGRMMGAVLIGETDLEETFENLILNQMNLSAYGEDLLDPNIDIEDYFD
What is the function of this protein?
Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response (By similarity).  Required for normal sarcomere structure and muscle fiber integrity (By similarity).
What are the official names of this protein?
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, myofibril, sarcomere.
Protein: GATA_RHOBA
Sequence: MLHSASEILKQLDSGEVTAVEVIAQSLAAIRASQPTINAFTHVAEETAMQAAEAVDADRKAGKTLGPLAGLPVAIKDVLCTSDMPTTCSSKMLEGFVPPYDATVVARLKSAGAIVVGKTNMDEFAMGASTETSAMGVTGNPWDTTKTPGGSSGGAAAAVAAGAVPLSLGTDTGGSIRQPAAFCGITGLKPTYGRVSRYGLVAFASSLDQAGPMGWSVDDVAIGLQAMAGYDPRDSTSVNAEVPDFTPAMAAEDVRGMRIGVLREGLDQDGISPAVRDALATAESVFREQGAEIVEVELPHSKYWVPTYYVIAPCEASSNLSRFDGAHYGYRVADAEIAAADSGPLEAMYSLSRAGGFGSEVKRRIMVGTYALSEGYYDAYYNQALKVRRLIRNDYDAAFQQVDLMLGPVTPSPAFALNEKTDDPIAMYLCDLFTVGANLAGVPAISLPGGFDAVGLPVGVQLQAPVMEETRLLRAGNVFQMASDFHTRRPPTFTANHSQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DID5A_ECHOC
Sequence: MIPVLLVTICLAVFPFQGSSIILESGNINDYEIVYPKKVAVLPTGAMNSAHPCCDPVTCQPKQGEHCISGPCCRNCKFLNSGTICKKTMLDGLNDYCTGVTSDCPRNPYKGKEDD
What is the function of this protein?
Poor inhibitor of platelet aggregation.  The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1.  Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low.
What are the official names of this protein?
Disintegrin EO5A, Eo-12.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YCF42_PORPU
Sequence: MISGHNCLQVGQIAPDFSATAVYDQEFKTIKLSDFKNKYVILFFYPLDFTFVCPTEITAFSDKYSDFSELNTEILGVSVDSEYSHLAWLQTDRESGGLGDLEYPLVSDLKKEISIAYNVLNSGGVALRGLFIIDPKGIIQYSTVNNLEFGRSVEETLRVLQAIQYVQAHPDEVCPANWKPGDRTMNPDPIKSKNYFAAA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Putative peroxiredoxin ycf42, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HNH83_ECOLX
Sequence: MKRINKTAEDQFLINFKAQNPNGTWDEFRNHEQGILYKRLKQHICNDQMYLCAYCEIDLDRENEHEIKVEHFKSKSGSLPGGSNWHLEWSNLLAVCLGGTNTGDDFELPANLSCDSYKSHYEDKNKINDKDWTGKILLPLTLPDAHNFFTFEKVTGKLLPNESYCNTISIDGKPAAETLSIVTKTIEVLNLNCSRLNNARRKLLFHFNNCARERNLRKLHNLLLQWNQGEPKFFQTTRDIIIRDDRICQGLLNGTIRY
What is the function of this protein?
Putative HNH endonuclease component of antiviral defense system retron Ec83, composed of a non-coding RNA (ncRNA), a reverse transcriptase (RT), a probable ATPase and this protein.  Expression of retron Ec78 confers protection against bacteriophage T2, T4 and T6.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T4 but do not collapse, at MOI 2 cultures enter growth stasis.
What are the official names of this protein?
Retron Ec83 putative HNH endonuclease, TIGR02646 family protein.
Protein: TRPC_BEII9
Sequence: MADILKRIEAYKRQEIAQAKQSVSLDALRRQCESVEKPRGFIKALAAKQAEGRMALIAEIKKASPSKGLIRADFDPPALARAYEEGGAACLSVLTDTPSFQGSPEFLTIARQAVSLPALRKDFLFDPYQVFEARAWGADCILIIMACVDDELAGALRDAARELGMDCLVEVHDEAELIRALRLETPLIGINNRDLRTFNVSLETSERLAAKIPDDRMIVGESGIFTAQDCARLKAHRIGTVLVGESLMREQDVTAATRRLLDLPPEAVTGPVHAVLES
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ISCA_ECO55
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: E4PD_YERPS
Sequence: MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQSEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCIIPIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTINVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAKSGF
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAG2P_AGEOR
Sequence: MRAIISLILISAMVFSMIAAVPXXEGLQLSEDERGGCLPHNRFCNALSGPRCCSGLKCKELSIWDSICLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1p, U2-AGTX-Ao1p, Agel_15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MATK_PENDO
Sequence: MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHDHGLNKSMIFLENQGYGNKFSSLIVKRLIIRMDQQNHLIISANDSNQNPFFGHNNNLYSQMISAGFAVIVEIPFSLRLVSYSQGEEVAKSHNLQSIHSIFPFLEDKFSHLNYVLDVLIPHPIHLEILVQALRYWVKDASSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFLFLYNSHACEYESIFLFLRNQSSHLRSTSSGVFLERIYFYGKIEYLVEVFYNDFQNNLWLFKDPFIHFIRYQGKAILASKDTSLLMNKWKYYFVDLWQYYFYMWSQSGRVRINQLSKYSLDFLGYLSSVRLNPSAVRSQMLENSFIIDNAMKTLDTRIPIISLIGSLSKAKFCNTLGHPISKPTWADSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKSTVRAFLKRLGSEFLEEFFTETEEEHVFSLIFPRGFFTLRKLYRGRIWYLDIICINALVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL5_UREP2
Sequence: MAFLKDLYKNKVAKDLQKEFAYSSVMQIPKIEKVVINAGIGNAVADKKHLEAAISELTLITGQRPVETKAKKSIATFKLRAGQSIGAKVTLRGDRMWAFIETLFNIALPRVRDFKGISNNSFDNQGNYTLGIKEQIIFPQVVYDDVKSVRGFDVTFVTTAKTAQEAKALLVGLGAPFQKVRGDK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: OBG_HELPS
Sequence: MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCAGKKGEDKIIVVPPGTQVFVDDALWLDLVEPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAKPKIANYEFTTLVPNLGVVSVDEKSEFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAFVLDASRLDLGIKEQYQRLRLELEKFSPALANKPFGVLLNKCDVVENIDEMAKDFCTFLNLEAQKLEAFGLEPYLGFLHPHLTSDFENNPNEKSALFVLPLSALSALNTHALKFVLLEALP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_STAAS
Sequence: MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQSVADQGCKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPCEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYSVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVGQ
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_STAAS
Sequence: MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDTHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTSIPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEANKTIVNKHLY
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ISCR_VIBPA
Sequence: MKLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGADAHSIAIGTVIAAVDESVDATKCQGKGDCQGGTRCLTHTLWRDLSSRISDFLNNITLGELMTDNEVLEISDRQDIGLAVTHGLSNKNTTAAPIGVNVRS
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: M2_I77AG
Sequence: MSLLTEVETPTKNGWECKCSDSSDPLIIAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQSVVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RH39_ORYSJ
Sequence: MAMAGAAGRCLMLTRPSPLLRLRLLRAALATTTTTTTAAGASAVTAPTEPETTAREAPSRHELLLERLRQRHLKGVPAATPRPAQREKGRGGGGGGAQELQQKRRVEVVDSFEELGLGEEVMAALGEMGISKPTEIQCVGVPAVLAGTSVVLGSHTGSGKTLAYLLPLVQLLRRDEAMLGMSMKPRRPRAVVLCPTRELTEQVFRVAKSISHHARFRSTMVSGGSRIRPQEDSLNMPVDMVVGTPGRILDHIKDGNMVYGDIKYLVLDEADTMFDQGFGPDIRKFLAPLKNRAAKPGDQGFQTVLVTATMTKAVQKLIDEEFEGIVHLRTTTFQKRVATARHDFIKLSGSENKLEALLQVLEPSLAKGNKVMVFCNTLNSSRAVDHFLTENQISTVNYHGEVPAEERVENLNKFRNEEGDCPTLVCTDLAARGLDLDVDHVIMFDFPSNSIDYLHRTGRTARMGAKGKVTSLVAKKDVTLATRIEEAMKKNESLEALTTNNVRRAAVNPQYTSTKGRPSALKVVNQKGRRGVALQTKSSRIVKDTTSSRRRSPIRSQPRSKSTSSGKAKPVRSAKPSKSSSPSPKVAKSRPRPEGRKGDALNKLGSKLSVVGFRGRSSGKSAQAS
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 39.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: LEPA_STAA9
Sequence: MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOY_LISMH
Sequence: MIFKVFYQETLTETPVREKTQSLYVEAESEVKVRQLLKDEPFHIEFVEKISDAHLAYEKENPDFALWEK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RL7_STRP4
Sequence: MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAADAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVATAEAEEIKAKLEEAGASVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ALF_PLAFK
Sequence: MNAPKKLPADVAEELATTAQKLVQAGKGILAADESTQTIKKRFDNIKLENTIENRASYRDLLFGTKGLGKFISGAILFEETLFQKNEAGVPMVNLLHNENIIPGIKVDKGLVNIPCTDEEKSTQGLDGLAERCKEYYKAGARFAKWRTVLVIDTAKGKPTDLSNHETAWGLARYASICQQNRLVPIVEPEILADGPHSIEVCAVVTQKVLSCVFKALQENGVLLEGALLKPNMVTAGYECTAKTTTQDVGFLTVRTLRRTVPPALPGVVFLSGGQSEEEASVNLNSINALGPHPWALTFSYGRALQASVLNTWQGKKENVAKAREVLLQRAEANSLATYGKYKGGAGGENAGASLYEKKYVY
What is the function of this protein?
Plays a key role in glycolysis by catalyzing the cleavage of fructose 1,6-bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate (PubMed:3285469, PubMed:2204832).  Independently of its catalytic activity, connects the actin filaments, and thus the actomyosin motor, to cell surface adhesins of the thrombospondin-related anonymous protein (TRAP), the erythrocyte binding ligand (EBL) and reticulocyte binding homolog (RH) protein families; this interaction is probably involved in transducing the motor force across the parasite surface required for sporozoite and ookinete gliding motility and merozoite invasion (By similarity).  Stimulates actin polymerisation (By similarity).
What are the official names of this protein?
Fructose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Host cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DMS10_PHAJA
Sequence: ALWKSLLKGAGQLVGGVVQHFMGSQGQPES
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-J10, DRS-J10.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.