PharMolix/UniProtQA huggingface dataset:
Protein: BRPF3_MOUSE
Sequence: MRKPRRKSRQNAEGRRSPSPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKENSEQPQFPAKSKKPSSKGKRKESCSKHASGTSFHLPQPSFRVVDTGSQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDIAWLDMVNEKRRADGHSSVSADTFELLVDRLEKESYLESRSSGAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTTFTVRKTAYCEAHSPSVAVARRKGDSPRSLSEVGDEDGPKEGGGEEEQEEAEEEGQEGQGGVGSPLKGVSKKGKMSLKQKIKKEPEEAGREAPSITLPMVTVPQIPSYRLNKICSGLSFQRKTQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQEKDSAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGGAILRHARRQAENIGYDPERGTHLPESPRLEDFYRFSWEDVDNILIPENRAHLSPEAQLKELLEKLDLVSTMRSSGARTRRVRMLRREINALRQKLAQPPPPQLLSLNKTVPNGELPAGSRGDTAVLEQAQQEEPEEEGDRDDSKLPAPPTLEPTGPAPSLSEQESPPDPPTLKPISDSKPSSRFLKSRKVEDEELLEKSALQLGSEPLQCLLSDNGIDRLSLTNPDSHPDTPLGTVGRRTSVLFKKAKNGVKLQRGPDGTLENGEDHGPEDDPASPASTEDEHYSRKRPRSRSCSDSEGERSPQQEEETGVTNGFGKHTESGSDSECSLGLSGGLAFEAGSGLTPPKRSRGKPALSRVPFLEGVNGDSDHSGSGRSLLMPFEDHGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGSHAFVTSSYL
What is the function of this protein?
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity.  Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins.  Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
What are the official names of this protein?
Bromodomain and PHD finger-containing protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10_FRATH
Sequence: MALRIEDKKAIVAEVAEQVSSALSAAVADYRGLTVNQMTSLRKQARESGVYLRVVRNNLARLAIKGTEFECLADALKGPLVLALSKDEPGAAAKLFKNFQKDHNAFEVKNLAMSGELFGPEKLDDFAKLPTREEALATLLNIMQAPVTKFVRTLNEIPSQAVRVFAAVGDSK
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL15_RICFE
Sequence: MKLNELYNNIGAKKNKKRIARGIGSGKGKTGGRGIKGQKSRSGVAIKGFEGGQTPMIKRLPKRGFNCISTKKYNIINIYNIEEALADGRLSAADTITKEKLVEVGVVNNKNNKKLVKLLSICSDDFASPLSLKLDAYSSKAKDLIEKAGGKLL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MIAA_PSELT
Sequence: MIIITGPTAVGKTDLSIAICCKLNAEIVSIDSRQLYRYMDIGTGKPTLSQRKIVRHHLIDIVDPDEYYSVYQFRLDAIRAIQDIVKRGKIPLFAGGTGLYIDSLVRGIFEGVSRDEELRKQLLQKETQCPGVLRSMLERIDPELADRIHKNDLKRTVRALEIWIKSKEKPSELRKKVKPVGRFTVIILHRDREELYDRINLRVNEMFQAGLLDEVKDLMKRGYSKNLNALRTIGYQESIAHLEGKLNFESTVELVKKNTRHFARRQVIWFRRYKDAIVIDLSSSSYRDAVNTISRIVLQDFQHDSFYDGGFSYD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ATPB_BARQU
Sequence: MVKAVSSSKGAAKVEQKKSAARSGVKKNASKSQASLQDTSSPLKTSSKNAHAKKDVQAKGAVGEIKQVIGAVVDVQFEGALPNILNALETENLGNRLVLEVAQHLGENTVRTIAMDTTDGLTRGQKVFDTETQICVPVGEATLGRIMNVIGEPVDNVGPIATTKTRSIHQKAPEYVDQSTASEILVTGIKVVDLLAPYSKGGKVGLFGGAGVGKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYYEMIESRVNVNPKDNNGSTKGSKCALVYGQMNEPPGARARVALSGLTIAESFRDEGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGALQERITSTKTGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSFSRMLDPLVVGEEHYTVACQVQTILQRYRSLQDIIAILGMDELSEEDKLLVGRARKIERFLSQPFHVAETFTGSPGKLVPLEETIKGFKGLCAGDYDDLPEAAFYMVGSIDEALEKGKRLIAEAAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECA_GEOSM
Sequence: MFGALIKKLVGSKNERELKRMWPIVERINQLEPELVKLSDEELRGKTAQFKERYSRGESLDSMLPEAFAVCREAGKRVLGMRHFDVQLIGGMVLHSGKIAEMKTGEGKTLVATLPSYLNGISGRGVHVVTVNDYLAKRDSDWMGRIHKFLGLSVGVIVHGLEDYERREAYAADITYGTNNEFGFDYLRDNMKFDLSEYVQRPFNFAVVDEVDSILIDEARTPLIISGPTEDSTDKYYIIDRIIPLLKKGEVIEVEANTLSGKRKTYTGDFTVDEKAKSASLTEEGVLKVEKLLKIENLYDPRNMEILHHTQQALRAHALFKRDVDYVVRDNEVLIVDEFTGRLMPGRRWSDGLHQAIEAKEGAKIENENQTLATITFQNYFRMYEKLSGMTGTADTEAEEFHKIYKLDVVVIPTNRPLLRPDFPDVIYKTEREKFNAVIGEIKELHEKGQPILVGTISIEKSEELSELLKRQGIPHFVLNAKQHEKEAEIVAQAGRKGMVTIATNMAGRGTDIVLGGNPDGLARQEFNGTPETRTEEFMAAFIETLSKDLPEKELLQSLEREYPGIMPVVAACLKQGGEIDLEELERQVLAEHQKQFNLLVDKNKPVCAAEHDEVVALGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLQDDLLRIFGSERVSMIMDKLGIEEGEAITHGLITRAIENAQKKVEAHNFEIRKHLIEYDDVMNKQREVIYTQRKEILGGNEIRESFTGMMEEAVGDIVAAYVIDRTPAREWDWQGITDTVQKVFGFHLDLTPDLMDRITPVNFDETLRTTARERFQQRLTEFGDDLMDHLIKVIMLQVIDAQWKDHLLSIDHLKEGIGLRGYGQKDPKQEYKREAYKLFMDMMLRIREEVVEKIFWVQVGSEEEMEQFELEQPQQRMVFNLVDEEAAAPAQAPSKSKRSAGRNDPCPCGSGQKYKKCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: IDI2_PYRNV
Sequence: MEIDRRKNDHIYLASSEISQVGSPWFDEVILIHNALPELDLSEVDTTAKFLGAEVKAPFGIGAMTGGTELAGKINAELAKAAEAFGIPIYVGSQRIALVKPEVRWTFEVVKKNAPTVPKVANLGAPQLVELDEVKLAEWVSQAVDMVDAHAVAIHLNAAQEAVQPEGEPRFRGVLEKIKVVKRAAGRPLIVKEVGNGISREVAARLAGVADAIDVGGYGGTSFIAIEGARAAGAGAQLRRRIAETFKLWGIPTAASICEAKSGYGGYIIASGGIRSGLDGVKALALGASFFTMSQPLLKAALEGRLKEEIETVVAEVKTAMFLIGARTVKDIASAPRVYGPRLRSWLEQRGLTC
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REPC_BPMU
Sequence: MKSNFIEKNNTEKSIWCSPQEIMAADGMPGSVAGVHYRANVQGWTKQKKEGVKGGKAVEYDVMSMPTKEREQVIAHLGLSTPDTGAQANEKQDSSELINKLTTTLINMIEELEPDEARKALKLLSKGGLLALMPLVFNEQKLYSFIGFSQQSIQTLMMLDALPEEKRKEILSKYGIHEQESVVVPSQEPQEVKKAV
What is the function of this protein?
Promotes latency by binding operators O1 and O2 in the enhancer/operator region, thereby repressing the transcription from the Pe (early) promoter and blocking the expression of the genes required for replication (lytic growth).  Competes with DDE-recombinase A for binding to the internal activation sequence (IAS), which overlaps O1 and O2.  The outcome of this competition determines if the virus enters latency or starts replication.  Makes the cell immune to superinfection by repressing genes expression of any subsequent incoming viral genome.
What are the official names of this protein?
Repressor protein c, Repc, CI, Gene product 1, gp1, Mu repressor, MuR.
What is the protein family that this protein belongs to?
Belongs to the mulikevirus repressor c protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: OBG_COXBN
Sequence: MKFVDEAFVRVEAGNGGHGCLSFRREKFIPRGGPDGGDGGDGGSVYFVADKSVNTLVEFRYQRLLRAQNGQPGMGRLRSGKKGEDLIVPVPLGTTVYDKETSELIGDLIEAGDKLCVARGGRHGLGNTHFKSSTNRAPRRTTSGEEGEARELKLELKLLADVGLLGLPNAGKSTFIHAVSKATPKIADYPFTTLYPHLGVVRVEEYRSFVIADIPGLIEGASEGAGLGVQFLKHLERTQLLLHIVDIAPLDGSDPVQSIQAIISELEQFSQNLSQKPRWLVFNKIDLLPPDVAQARCQEIINRLNWKGPVYKISAIKRQGTELLCYDLMSFLETNQRSI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUQ_AROAE
Sequence: MIDDAAPPYVGRFAPSPSGPLHFGSLVAAVGSFLDARAHHGQWRLRIEDVDTPRTVPGAAQDILATLERFGFEWDGKPVWQSARLDAYRDAFERLRAAGQVFPCACTRREMADSALARDGSRLYPGTCRNGLPPGRSAHAWRVRAHGRIAFADRIQGPQEEDLATEVGDYVVLRGDGQFAYQLAVVVDDAAAGVTDIVRGADLLGSTGRQIHLQHLLGYPTPAYAHLPVVVNTAGEKLSKQTLAAPVAALPPARALFAALTFLGQNPPPALGRASLRETWKWAVTHWSLVDVPRQLQAEAPGAFSARARENPSSL
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: FENR2_BACHK
Sequence: MKVAENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKVRAQELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGIFKLVTNKQTHYSKSVIITAGNGAFQPRRLELEGTAKYEKKNLHYFVDDMNKFAGKRVVVFGGGDSAVDWTMMLEPIADKVTIVHRRDKFRAHEHSVESLMNSRAEVSTPYVPVELIGDDKIEQVVLQHVKTEEKIIIDVDDVIVNYGFVSSLGPIKNWGLDIQKNSILVNSKMETNIPGIYAAGDICTYEGKVKLIACGFGEAPTAVNNAKAYFDPNAKLQPMHSSSMF
What are the official names of this protein?
Ferredoxin--NADP reductase 2, FNR 2, Fd-NADP(+) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: NAP1_YEAST
Sequence: MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS
What is the function of this protein?
Acidic protein, which assembles histones into an octamer (in vitro).  Involved in the regulation of the localization and the function of the septins during mitosis.  Involved in the function of B-type cyclins.
What are the official names of this protein?
Nucleosome assembly protein.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Bud neck. Note=Phosphorylation by CK2 promotes the import into the nucleus.
Protein: DAPB_PSEU2
Sequence: MRRIAVVGAAGRMGKTLIEAVQQAPGAGLTAAIDRPDSTLVGADAGELAALGRIGVPLSGDLAKVADEFDVLIDFTHPSVTLKNLAFCRKAGKAMIIGTTGFSAEEKQRLEEAGKDIPIVFAANFSVGVNLCLKLLDTAARVLGDEVDIEITEAHHRHKVDAPSGTALRMGEVVANALGRDLEKVAVYGREGQTGARDRQTIGFATLRAGDIVGDHTVLFAADGERVEITHKASSRMTFAKGAVRAAMWLDGKAPGLYDMQDVLGLH
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_SOLTU
Sequence: MLTITSYFGFLLAALTITSALFIGLSKTRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ADH_DROAD
Sequence: MVIANSNIIFVAGLGGIGLDTSREIVKSGPKNLVLLDRIDNPAAIAELSALNPKVTVTFYPYDVTVPLDETKKLLKTIFDKLKTVDLLINGAGILDDNQIERTIAVNFTGTVNTTTAIMDFWDKRKGGPGGVVANICSVTGFNSIYQVPVYSASKAAALSFTTSFRKLAGITGVTAYSINPGITKTVLVHKFNSWLGVEPRVAELLLEHPTQTTLQCGQNFVKAIEANQNGAIWKLDLGRLDAIEWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MSI1_SOLLC
Sequence: MGKDEDEMRGEIEERLINEEYKIWKKNTPFLYDLVITHALEWPSLTVEWLPDREEPSGKDYSVQKMILGTHTSENEPNYLMLAQVQLPLEDAENDARHYDDDRSEFGGFGCANGKVQIIQQINHDGEVNRARYMPQNPFIIATKTVSAEVYVFDYSKHPSKPPLDGACNPDLRLRGHSTEGYGLSWSQFKQGHLLSGSDDSHICLWDINATPKNKALEAMQIFKVHEGVVEDVAWHLRHEYLFGSVGDDQYLHVWDLRTPSVTKPIQSVVAHQSEVNCLAFNPFNEWVVATGSTDKTVKLFDLRKISTALHTLDCHKEEVFQVGWNPKNETILASCCLGRRLMVWDLSRIDEEQTPEDAEDGPPELLFIHGGHTSKISDFSWNPCEDWVVASVAEDNILQIWQMAENIYHDEDDLPGDDAPKGP
What are the official names of this protein?
WD-40 repeat-containing protein MSI1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BACR_HALVA
Sequence: MPAPEGEAIWLWLGTAGMFLGMLYFIARGWGETDSRRQKFYIATILITAIAFVNYLAMALGFGLTIVEIAGEQRPIYWARYSDWLFTTPLLLYDLGLLAGADRNTISSLVSLDVLMIGTGLVATLSAGSGVLSAGAERLVWWGISTAFLLVLLYFLFSSLSGRVADLPSDTRSTFKTLRNLVTVVWLVYPVWWLVGTEGIGLVGIGIETAGFMVIDLVAKVGFGIILLRSHGVLDGAAETTGAGATATAD
What is the function of this protein?
Light-driven proton pump.
What are the official names of this protein?
Cruxrhodopsin-3, COP-3, CR-3.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYH_YERPS
Sequence: MAKNIQAIRGMNDYLPADTAIWQRIESILKQVLSGYGYSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQLGAEVFGLPGPDIDAELILLTARWWRALGIFEHVKLELNSIGSLAARADYREALVAFLEQHVEVLDEDCKRRMYSNPLRVLDSKNPDVQQLLDDAPKLSDYLDEESKQHFAGLCELLDKASIPYTVNERLVRGLDYYNRTVFEWVTHSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNADFQVPATVDAYVISSGEGAQSAAMLLAESLRDALPTLKIMTNYGGGNVKKQFTRADKWGARVALMLGESEVAAQQVVVKDLRNGEQETLAQADVAARLALMLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVC_MOUSE
Sequence: MTCTKDARLQLGREALQAAPTLLVPAVLLGGVLGLGLGLWLGCRASHLRARLQKDDRKRLLGSSEPPAQSLRDTGSQAKARRRQRETTRDEDAPEVCEPSLSGNITAFALKARVVYPINQKFRPLADGSSHPSLHENLTQAAAILPHLPHQPAEASPASSLGSLSQAGKEDGSSSSSMRSTYSDDRILQCAFLRVGSFPEILACESVDIDLCVCSLHLKDLLQVDTALRQEKHLMFIQILKACLLDFFPKKKPDDELCQKVLSKQEHDLEELEKGLQARLANTEMLGTGDSGYVSLADVERKERELSEQLIDNMGAFWKQMESIQPTLMDQFKCSSSKARQFMMTLTGRMIVAEGLLHDSQDLHVLDTLERTMGRSHLARMVEFLRTQIQEETKCRLAAISRGLELLTVQGQLSGRQKEELLTQQHKAFWEEAERFGREFTQRGKDLVQASQARQAEAAAELTQTQEEERRSFLADSQLTSDPGEFLKAFHEVLERQRLTRSDQEGDEDTRITEAMAALCQELYCSTMGTFQKFVDSLFLKTLPEVTSLPVAECETLRQQVQEQAARQLGQADRFRRRQWGLLCDLLEQDKRVWLEEGTLSTVLQRQLRDHHESTIHGVLSRFSGLSEESSRGILQGHELLLCSALRRLALRGTTITALAQMRLSGKKRLLQELHEQLALEQGVSPCLEEHQWQLLRALEARIQEEAARLEDEAQQTGLRLQQQLLAEAQEAGRLLQLHMERVIGQALLVHARNVASKGRTREKEDFKRTLVETVVESVYVTSTSVNRLVQAHYQAVGKLLQAHEEQLLQRLKTLQGERINAYKLWKKQEFSDPSLESQTADGTHGASQGVQQRMLSQQKRLLDQFTKHQQGRLNSQRQKAQELDQLQAQLETQLQEAEQTLISELSTLARVPLPENKPFSNKRGLPEKPVRTKRKKPPPREREDLGTPNDDHLALADHTTGPLSTTYSASPPIRVHSGGRLDQQDSEAGDGESTSKILQKGSNL
What is the function of this protein?
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:17660199, PubMed:24582806).  Involved in endochondral growth and skeletal development (PubMed:17660199).
What are the official names of this protein?
EvC complex member EVC, Ellis-van Creveld syndrome protein homolog.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane. Note=EVC2 is required for the localization of EVC at the base of primary cilia (PubMed:21356043). The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806).
Protein: RECA_SALSV
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNATPDFAVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRCH2_MOUSE
Sequence: MAASQGGGGNSGGGGCSGGGSGGGGGAAGGGGGGGGGGGGGAGAGGGGGCGGTVAVPIPVPTLFGQPFPNGPQWHPGSLQPQHTVRSLDRALEEAGNSGILSLSGRKLREFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVSIPEEIGKLKDLMELDVSCNEIQVLPQQMGKLHSLKELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLNIQACCRMDKKPDSLDLPSLNKRMPSQPLTDSMEDFYPNKNHGPDSGIGSDNGEKRLSTTEPSDDDTISLHSQVSESNREQTSRNDSHITGSKPDSQKDQEVYDFIDPNTEDVAVPEEGDTHIGSFVSFLKGKEKSSEKSQKNEEPPNEKKVDKEQLLPEEEDDDLKEVTDLRKIAAQLLKQEQKNRILNHSTSVMRNKLKQTVECEKSVPADEGNSPLSPLAWQPLENQKDQIVDQQWPESQPIIWQNEERRRSKQIRKEYFKYKSTRKNSSGNENEEQESDNAHMSAQSPVSSEEYDRSDGFSHGPFGLKPRSAFSRASRQEYGAADPGFTMRRKMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPSPAVPKLSMAKCRRNVENFLDACKKLGVSQERLCLPHHILEERGLVKVGVTVQALLELPTTKASQLSMA
What is the function of this protein?
May play a role in the organization of the cytoskeleton.
What are the official names of this protein?
Leucine-rich repeat and calponin homology domain-containing protein 2.
Protein: TERB_ALCSP
Sequence: MRMSFFDKVKGALTSGREELTRQVGRYKNKKFMQGTVAVCARIAVASDGVSSEEKQKMIGFLRSSEELKVFDTAEVIEFFNKLVTSFDFDLEIGKGETMKYILALKDQPEAAQLALRVGICR
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Tellurium resistance protein TerB.
Protein: DTD_ECOK1
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBW_STAAR
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKEKNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: RL30_DEHMC
Sequence: MAKIKITWVKSTIGYKFDQAATIKALGFKKLNQSVIQDDSSAIRGMILKVRHLVVLEEVT
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MSRR_STAAR
Sequence: MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED
What is the function of this protein?
Involved in SarA attenuation.  Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors (By similarity).
What are the official names of this protein?
Regulatory protein MsrR.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: FLGH_CUPPJ
Sequence: MLSRLGARVLYCLAGLALLASGGCALMPREPLVQLPTTARAEPRPMGPATGSIFASSYAGNPLFEDRRPRNVGDILTIVITENVNATKNSGTNASRTGSTSMAFDAVPKALAGLFSSSSNASINGANALKASGGASAANTFNGTITVTVLEVLANGNLVVSGEKQLAINQGAEFIRFSGVVNPRTITGDNGVLSTQVADARIEYTAKGYIDEAQNMGWLQRFFLNVSPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.