PharMolix/UniProtQA huggingface dataset:
Protein: PDXJ_THEYD
Sequence: MVILGVNVDHIATVRQARKTFEPDPVMAATLAILGGADGITIHLREDRRHIQDRDLKILREVVPCELNLEMAATEEMINIALNIKPDMVTIVPEKRQELTTEGGLNVIELKDSLKEAIKKIKDAGIPVSLFINPERNDIECSKDIGADMVEIHTGYYSESRGDVQLKELERIKDAVAYSISLGLKTNAGHGLNYYNVKSIAAIKGLRGLYIGHSIIARAVLVGIEKAVREMKNLIKEACINA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_BEUC1
Sequence: MARLVGVDLPRDKRLEVALTYIYGVGRTRAADTLKATGISPDLRVKDLGDAEIVALRDHLEGNYKIEGDLRREVAADIRRKVEIGSYEGLRHRRGLPVRGQRTKTNARTRKGPKRTVAGKKKAGRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DER_HELHP
Sequence: MKTIAILGKPNVGKSSLFNRLIKQHLAITSDVSGTTRDVKRACFDISGVEVELLDTGGIDKAEGLFAKVSANSLKAGQEADLVLYMVDGNVVPQDDDIAYFRTIQKAKKPLVLVINKVDNDKIKQQAWDFACFGAEQMYFISVHHNRGLSILLEAIFELLSLAKEQSLSNNLRSQMDNEEIDESLEEFLGILESTPNKSEENIAVGIIGRVNVGKSSLLNALLGKERSVVSEVAGTTIDPVDDEMDIEGKRVRFVDTAGIRRASKIWGIEKFALLRTNAALAQSHIVILVLDASESFVELDEKISSLIPKHALGVIVVLNKWDKKHKEYKEIIKEFKHRFPFLSFAPVMTLSALNGRNIDKLKKEILKVYQRFAYRIPTSALNDVIAQAVAHHHIPSDHGKIVKIYYATQYATHPPQIALVSNRPESLHFSYKRYIINMLREQFDFEGVPILLSVKGKNAKDEENTSAKKESPSKVSHRESKNRRFV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MNME_BACAN
Sequence: MEFDTIAAISTALGEGAIAIVRVSGDDAVEKVNRIFKGKDLTEVPSHTIHYGHIVDLDTNQVIEEVMVSIMRAPRTFTRENIVEINCHGGLVSVNKVLQLILAQGVRLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAINQMEGRLSKLIGRLRQDILETLAHVEVNIDYPEYDDVEEMTHNILIEKATHVRAEIAKILETSKQGKILREGIATAIIGRPNVGKSSLLNSLVQEKKAIVTDIAGTTRDVIEEYVNVRGVPLKLIDTAGIRETEDVVERIGVERSKEMMSQADLVLVVVNYSETLTNEDEELFRAVQGKDFIVIVNKTDLPQAIDMERVIELAAGNRVITTSLIEEQGIDELEKAIADLFFEGTIDSADVTYVSNARHIGLLTQAGKTIGDAIEAIENGVPIDMVQIDLTRTWEILGEITGDTVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_DICNV
Sequence: MISRKYFGTDGVRGEVGKEPMTPQWVMHLAWAVGSVLCDNGFAGEKVLVGKDTRLSGYLFENAIIAGLSAAGMEVHMLGVMPTPGIAYFTRTFNAAAGVVVSASHNVFSDNGVKVFARGGYKLPDSAEQQIEAYLDKPMTLVAPAKMGKVYRVAEARGRYIEFCKNSIPLNLPFHRLKLVLDCAHGATYAVAPDVFRELGAQVIVTNAAPNGCNINDGCGSTHPEALQQRVCQEQADIGIAFDGDGDRVIMVDQRGRIIDGDAILYIIAKYRAFKGEQLNTIVGTLMTNLGLEQSLRKMGITLHRAQVGDRYVLEQLQLLQARVGGENSGHIICLDRNSTGDGIIAALQVLAAILEMETTLEDLIADLALTTQVLKSVTVVERDAVINSAAVQTAIQNAEEKLRNRGRLLLRPSGTEPKIRVMAEGDDETLLNDVVNELIATIKEQEKTHA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SETBP_HUMAN
Sequence: MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQEFSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQAYERPQKHSTLHYDTGLPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPALEPVASFAKAQGKKGSAGNTWSQLSNNNKDLLLGGVAPSPSSHSSPAPPSSSAECNGLQPLVDQDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQKAFDNTEGKREGYSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSIKAVVEKIMPEKALASGITMSSEVVNRILSNSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIPGGVSKPRKPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKRRWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPLLTVETIHEGTSTSPVSPISREFPGTKKRKRRRNLAKLAQLVPGEDKPMSEMKFHKKVGKLGVLDKKTIKTINKMKTLKRKNILNQILSCSSSVALKAKAPPETSPGAAAIESKLGKQINVSKRGTIYIGKKRGRKPRAELPPPSEEPKTAIKHPRPVSSQPDVPAVPSNFQSLVASSPAAMHPLSTQLGGSNGNLSPASTETNFSELKTMPNLQPISALPTKTQKGIHSGTWKLSPPRLMANSPSHLCEIGSLKEITLSPVSESHSEETIPSDSGIGTDNNSTSDQAEKSSESRRRYSFDFCSLDNPEAIPSDTSTKNRHGHRQKHLIVDNFLAHESLKKPKHKRKRKSLQNRDDLQFLADLEELITKFQVFRISHRSYTFYHENPYPSIFRINFDHYYPVPYIQYDPLLYLRRTSDLKSKKKRGRPAKTNDTMTKVPFLQGFSYPIPSGSYYAPYGMPYTSMPMMNLGYYGQYPAPLYLSHTLGAASPFMRPTVPPPQFHTNSHVKMSGAAKHKAKHGVHLQGPVSMGLGDMQPSLNPPKVGSASLSSGRLHKRKHKHKHKHKEDRILGTHDNLSGLFAGKATGFSSHILSERLSSADKELPLVSEKNKHKEKQKHQHSEAGHKASKNNFEVDTLSTLSLSDAQHWTQAKEKGDLSSEPVDSCTKRYSGSGGDGGSTRSENLDVFSEMNPSNDKWDSDVSGSKRRSYEGFGTYREKDIQAFKMNRKERSSYDSSMSPGMPSPHLKVDQTAVHSKNEGSVPTMMTRKKPAAVDSVTIPPAPVLSLLAASAATSDAVGSSLKKRFKRREIEAIQCEVRKMCNYTKILSTKKNLDHVNKILKAKRLQRQSKTGNNFVKKRRGRPRKQPTQFDEDSRDQMPVLEKCIDLPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLPPPPPLPKTPRGGKRKHKPQAPAQPPQQSPPQQPLPQEEEVKAKRQRKSRGSESEVLP
What are the official names of this protein?
SET-binding protein, SEB.
What are the subcellular locations of this protein?
Nucleus.
Protein: YOBD_SALPA
Sequence: MTITDLVLILFIAALLVYALYDQFIMPRRNGPTLLSIALLRRGRVDSVIFVGLVAILIYNNVTSHGAQMTTWLLSALALMGFYIFWIRTPRIIFKQRGFFFANVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVHNIDDLEKIYKLLIENQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_CLAMS
Sequence: MIVRHLSLGDFRNYTRADVALLPGATLFVGSNGQGKTNLVEALGFLSTLGSHRVSTDQALVRQGAESAVIRALLQHAGRELRVEVQINRSAANRAQVNGTATKTRELPRYFSSVLFAPEDLALVRGDPSGRRRLLDQLLVLRTPRLAGVLSDYDRALKQRNTLLKSARARGMKADQLSTLDIWDERLVAIGSQIIAARGALVESLQPELARAYLAVAGSDHGPSARPELSILADDPGEDDVADETGARDGGRFTRTEDVVPVFTAAIARMRPRELERGLTLVGPHRDDVLFRLNGLPAKGYASHGESWSFALAIKLASAELLRRDSQTGDPVLILDDVFAELDQARRGRLAEAVTGFEQVLITAAVFEDVPEHLAANAVHIRAGAIVESPTPASASEPASPGEDGGAA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM_DROME
Sequence: MARPIFPNQQKIAEKLIILNDRGLGILTRIYNIKKACGDTKSKPGFLSEKSLESSIKFIVKRFPNIDVKGLNAIVNIKAEIIKSLSLYYHTFVDLLDFKDNVCELLTTMDACQIHLDITLNFELTKYYLDLVVTYVSLMIVLSRVEDRKAVLGLYNAAYELQNNQADTGFPRLGQMILDYEVPLKKLAEEFIPHQRLLTSALRSLTSIYALRNLPADKWREMQKLSLVGNPAILLKAVRTDTMSCEYISLEAMDRWIIFGLLLNHQMLGQYPEVNKIWLSALESSWVVALFRDEVLQIHQYIQATFDGIKGYSKRIGEVKEAYNTAVQKAALMHRERRKFLRTALKELALIMTDQPGLLGPKAIFIFIGLCLARDEILWLLRHNDNPPLLKNKGKSNEDLVDRQLPELLFHMEELRALVRKYSQVMQRYYVQYLSGFDATDLNIRMQSLQMCPEDESIIFSSLYNTAAALTVKQVEDNELFYFRPFRLDWFRLQTYMSVGKAALRIAEHAELARLLDSMVFHTRVVDNLDEILVETSDLSIFCFYNKMFDDQFHMCLEFPAQNRYIIAFPLICSHFQNCTHEMCPEERHHIRERSLSVVNIFLEEMAKEAKNIITTICDEQCTMADALLPKHCAKILSVQSARKKKDKSKSKHFDDIRKPGDESYRKTREDLTTMDKLHMALTELCFAINYCPTVNVWEFAFAPREYLCQNLEHRFSRDLVGMVMFNQETMEIAKPSELLASVRAYMNVLQTVENYVHIDITRVFNNCLLQQTQALDSHGEKTIAALYNTWYSEVLLRRVSAGNIVFSINQKAFVPISPEGWVPFNPQEFSDLNELRALAELVGPYGIKTLNETLMWHIANQVQELKSLVSTNKEVLITLRTSFDKPEVMKEQFKRLQDVDRVLQRMTIIGVIICFRNLVHEALVDVLDKRIPFLLSSVKDFQEHLPGGDQIRVASEMASAAGLLCKVDPTLATTLKSKKPEFDEGEHLTACLLMVFVAVSIPKLARNENSFYRATIDGHSNNTHCMAAAINNIFGALFTICGQSDMEDRMKEFLALASSSLLRLGQESDKEATRNRESIYLLLDEIVKQSPFLTMDLLESCFPYVLIRNAYHGVYKQEQILGLAL
What is the function of this protein?
Plays a role during growth of the oocyte.
What are the official names of this protein?
Membrane-associated protein Hem, dHem-2.
What is the protein family that this protein belongs to?
Belongs to the HEM-1/HEM-2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: RS11_EHRCR
Sequence: MSVVYKKKKRNVVVGVVYIHATYNNIIVTVTDQQGHSLICTSAGACGFKGSKKATPYAAQETASHAVKTVVEQNGMKTVSIKVSGPGAGRESAIRAVQACNLNVTSIKDTTKLPHNGCKLPGRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: COAD_SALPB
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPC1_HELPY
Sequence: MALVKEVLVVLNRLSPFELQESWDNSGLNVGSENSEFSEIVACLEITLKIALNAPQNALIITHHPLIFKPLKTLNDEIYPGNILKILIQKNVSVISMHTNFDKTHLNKHFAHALLEFDGLVEKGLMLVKENANIEFDALVKKIKSSLGVGSLACVKSSQTIKDLAFVCGSGASMFSSLKAQSCLITGDVKYHDAMIAQSLGISLIDATHYYSERGFALIVAEILHSFNYLVTIENFKNPLQII
What is the function of this protein?
Converts GTP to dihydroneopterin triphosphate.  Is not active with GDP, GMP, ATP, CTP or UTP as substrate.
What are the official names of this protein?
GTP cyclohydrolase 1 type 2, GTP cyclohydrolase I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: RSMJ_RHOPA
Sequence: MAETARTAPAVDFVGGAVGYRFRSQAGRSHALLKATGLSPTRSLHVIDATAGLGRDAFLLASMGATVTLIERVPEVHALLAEALEAARAESDELAAIIGRMTLLHGDARVLLPTLQADVITIDPMHPPRTKTALVKQEMRLLRDLVGADPDVGELLAAALSADCGRVVLKWPLRAAAPPAARKPSHQIAGKTVRYDVYVRPRTT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT2_SHESH
Sequence: MGKLLFLFITLILFEQQSLAALPTGDSEKYLRARESMVQNQLSTRDIKDKRVLTAMREVPRHLFVPDLLVFKAYTDSPLPIGEGQTISQPYIVALMTELLELTGSERVLEIGTGSGYQAAVLSQVAKEVFTIEIKEKLCTKAGKLLDSLGYTNIQARCGDGYFGWNKEAPFDAIMITAAVDHVPPPLLAQLKDGGRLVLPLGNPFSYQNLVLVTRKGDDYRVWQISGVLFVPMTGHALKDSGEK
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase 2, L-isoaspartyl protein carboxyl methyltransferase 2, Protein L-isoaspartyl methyltransferase 2, Protein-beta-aspartate methyltransferase 2, PIMT 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_SHEFN
Sequence: MADVSNRVHLNPTTAQLVEIALLRGEGQLTANGALVAKTGERTGRSPNDRFIVKEANTEADIEWGKVNRPFDAGKFDALWGRVEAYLADKELFTSELEVGADDEHYIPVRVTTEFAWHQLFARNLFIAPETFNRGNKDTWQIINAPGFVCEPQRDGTNSEAAVILNFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAKGVLPMHCSANVGHDGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVVLDEQRVPDYKDTSLTENSRAAYPLEHIAQRKEDNRGAEPHAVVFLTCDVSGVLPPVSVLSKEQAAYHFLSGYTAKVGSTEMGSTSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGVGKRFDIPTTRAIVDAIVSGELKDVETVYIDKLNLNVPVSVSGVDTALLNPVNTWADKAEYDKYAQQLAQEFSDNFAKYKVSEAIKNAGPNV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEMP_CVMS
Sequence: MFNLFLTDTVWYVGQIIFIVAVCLMVTITVVAFLASIKLCIQLCGLCNTLVLSPSIYLYDRSKQLYKYYNEEVRPPPLEVDDIIIQTL
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: HFLD_METCA
Sequence: MIKTLDNQVIALAGLAQATHLVRQIAQRGSADAGDMEAVVRSVFAIDADDVPSVYGGVDKIKTGLQILDRQLAGFEPPDAELARYGATLILLERKLVSAPRLLETLRTGIEQVKEQAEYFGELNDTVYANLADLYQRTVSQLRPRVMVNGQPSHLTNSTNANRIRALLLAGIRSVVLWRQCGGERWKLLFQRSAMRKEARRLLQSSQ
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HXC4_RAT
Sequence: LVVMLESRFPGPARGVANCRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHDSPTPK
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C4, Homeobox protein R3.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOXI1_MOUSE
Sequence: MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGMPSPQRPTSFEGGGEYGTTPNPYLWLNGPAMTPPPYLPGTNASPFLPQAYGMQRQLLPSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDQRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDSSSSTSSLASEKTENGLLASSPKPTEPQEVLDTASPDTTTSSPEKRSSPAPSGTPCLNNFLSTMTAYVSGTNPISRSVATPGLSSEPIDKMGQNSLNFNSYTPLTNLSSHGNGGEWANPVATNALGYGGSVFNQFSPHFYNSINTNGILFPREGTEV
What is the function of this protein?
Transcriptional activator required for the development of normal hearing, sense of balance and kidney function.  Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear.  Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules.
What are the official names of this protein?
Forkhead box protein I1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3464_RHOCS
Sequence: MPSFDIVSKTDLAEVQNAIDGVLRELQNRFDFKGSKSTIERKENEITLHTEDKTKLSQLQEMVKGYFVRRKLDPGALDWGREENAAGGTLRQVVTVRQGIDQDLAKKIVKAVKDSKMKVQASIQGDELRITGKKIDDLQECIRLVKGLKIEQPLQYVNFRD
What are the official names of this protein?
UPF0234 protein RC1_3464.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: SYGA_ALIF1
Sequence: MQKYDIKTFQGMILALQDYWAQNGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMSTAYVQPSRRPTDGRYGENPNRLQHYYQFQVALKPSPDNIQELYLGSLEVLGIDPLVHDIRFVEDNWENPTLGAWGLGWEIWLNGMEVTQFTYFQQVGGLECKPVTGEITYGIERLAMYIQEVDSVYDLVWNIGPDGTAVTYGDIFHQNEVEQSTYNFEHADVDFLFGFFDQCEKESKELLELEKPLPLPAYERILKAAHAFNLLDARKAISVTERQRYILRIRNLTKAVAEAYYASREALGFPMCKKNEEK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_HAEIG
Sequence: MQGSVTEFLKPRLVDIEQISSTHAKVILEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEVLLNLKGLAVKVQNKDDVILTLNKSGIGPVVAADITHDGDVEIVNPDHVICHLTDENASISMRIRVQRGRGYVPASSRTHTQEERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIELETNGALEPEEAIRRAATILAEQLDAFVDLRDVRQPEIKEEKPEFDPILLRPVDDLELTVRSANCLKAETIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: VRAC_STAAR
Sequence: MQHYLLDSNQRLNVSFSKDSVAAYYHCFNQPYSKEVPPLMCASLWSKFDLFKKYANSELILTKSVINQTQKIKVDTIYVGHLEDIECRQIRNITRYTMALTLTKNDQHVITVTQTFIKAMK
What are the official names of this protein?
Protein VraC.
Protein: GATA_HELHP
Sequence: MITLKEALNKSENELKEIKTLLRQRVKENIELNAYIGEINESGSGVPILIKDNINVKGWEITCASKILKGYVSPYNASVITKLHENKMCAFGRANMDEFAMGSTTESSCYGRVKNPLDTSRVPGGSSGGSAAAVAAGLAIASLGSDTGGSIRQPAGFCGCVGLKPSYGRVSRYGLIAYSSSLDQIGPITQNVEDAALLLDAISGYDKQDSTSANLPSLNTFKDLDPNARYKVAILKDFLKDATPQIQEAYNHTIKILESMGHTIVEKSMLDTRYHISAYYIICTAEASSNLARFDGIRYGTRSESKNLKDVYLNTRSAYFGEEVKRRILLGSFVLSSGYYDAYYLKAQQVRKKICADYESIFNECDSILLPIAPSVAPKFGSTHSSLEMYLSDIYTIGVNLAGLPALCMPVSKDKNGLSIGMQFIGAKFKEQNILNIAYGLEKEINN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NOG1_TRYBB
Sequence: MSTIYNFKTVTVVPSYKDFIDIVLSKTQRKTPTVVHKGYHISRIRQFYMRKVKFTQKTINEKLTHILTEFPRMDDIHPFYGDLMHVLYDRDHYKVALGQVGAVRHMVDNVGRDYVRLLKYGDSLYRCKQLKRAALGRMATACKKLTSALVYLEKVRQHMSRLPSIDPNARTLLITGFPNVGKSSFMNKVTRADVEVQPYAFTTKSLFVGHTDFKYASWQVIDTPGILDHSLEERNVIEMQAITALAHLRACILFFMDLSTQCGHSIAQQVSLFKSIGPLFTGKPVIVVFNKSDLCTFDDITAEEQSLVMTAIEECGAKWITTSTLTDAGVGDLKTLACETLLAHRSEQKEGSGRFQAIQNRLYCAVPQKRDNVERPAYVPPSVEEIRQRLASGEPVRERRKTERDYEWENGGPGQYQPNERKTWDLENPEWVDDIIPDIMDGHNIYDNVDPDIHERLMELEAEEDARLQELELEASKKRPQYELHDSTVEAVRFIRDKIKVIKMERAMKNPSLRRTRRQSVAIEKFNKRTGSQVDRSATPGCSSETTNSSAKRGRSLSAAQEAVMRDRSSSHMSTKTTRGISSHSATRDRSLSVNRGEGYRDVNEKLRAVKLSKVVARPRNLQAKKGEGDRAIPNLRPKHLFTGKVKSNGRRDRR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYT_METKA
Sequence: MRLLFIHADEMSFEARQKTKIAEEEPPIKEAEVEDCLVVFAAVQEADEENPKAIAEAAVEEIEDVAGELKADRIVLYPYAHLADDLASPDVAVEVLKRMEGLLKERGYEVVRAPFGWYKAFRLACKGHPLSELSRTVTPEAAEEAEEEKIESEFLVYMDGELIPVEEVDLSELPEDFRHLVMHELGEERETGDEEPAHVKLMREKEICDHEPAADVGHVRWYPKGHVVRRCLAEYVENLMADLGAAVVETPVMYDLSEDAIREHADKFGERQYRIRAGNRALMLRYAACFGAFRLLADTTLSRRHLPLKIYELSQSFRLEQSGEVVGLKRLRAFTMPDLHTVCADMDEAVEEFLEQAKLCLEVGLDLGLEYEVVFRTTEKFLKERKEVLEELAEAMEKAYGDAKPVLVEVLPERKHYWECKVDFAFIDSLGRPIENPTVQIDVESGRRFGITYADESGDERHPVILHCSPTGSLERVICAILEGQYKRFEQEGKLPTLPTWLSPVQARVIPVSEKVLEEAEKVFEELKSEGFRVDLDDRDEPVGRKIRDAGEEWVPYVIVIGEEEVKKGTLSVTIREESTLKEQRREEMTLEELVERLERETEGKPRVPLTIPDRLSRRPRFGR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPB_PSESM
Sequence: MRTLPLNGSRNSSRLPTLLLAAGLAMTPWAPALAAGMEGMDHGSHSMPMGASSDAPAQSRTPIPPVTDADRAAVYTSHSGHQVHDSAINSYFVADKLEWQDANDGSALAWDLSGWIGGDIDRLLLRSEGERTNGKTEEAEVQALWGHAVSSSWDVVAGARQDFKPGAPQTWAAFGLQGQAISDLDVEATAFIGDAGQTAARLEADYDLLLTNDLILQPTGELNFYGKNDPQRGNGSGLSTSEFGLRLRYEITPQFAPYVGVTWNRSYGKTADYAREDDEDVAQARLVVGLRLWF
What is the function of this protein?
Exact function not known.  Could be involved in copper resistance (By similarity).
What are the official names of this protein?
Copper resistance protein B homolog.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: TORD_ECOSE
Sequence: MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVVRCRQYDSFGFYAALSQLLLVLVESDHQNR
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_SHIFL
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.