PharMolix/UniProtQA huggingface dataset:
Protein: MSCL_ACTP2
Sequence: MSILKEFREFAVKGNVVDMAVGVIIGGAFGKIVSSLVSDVVMPPIGWLIGGVDFKDLAIEIAPAKEGAEAVMLKYGAFIQNVFDFLIIAIAVFGMVKVINKIKKPAEAAPAEPTAEEKLLTEIRDLLKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYBR1_PONAB
Sequence: MAMEGYWRFLALLGSALLVGFLSVIFTLVWVLHYREGLGWDGSALEFNWHPVLMVTGFVFIQGIAIIVYRLSWTWKCSKLLMKSIHAGLNAVAAILAVISVVAVFENHNVNNIANMYSLHSWVGLIAVICYLLQLLAGFSVFLLPWAPLSLRAFLMPIHVYSGIVIFGTVIATALMGVTEKLIFSLRDPAYSTFPPEGVFFVNTLGLLILVFGALIFWIVTRPQWKRPKEPDSTILHPSGGTEQGARGSMPAYSGNNMDKSDSELNNEVAARKRNLALDEAGQRSTM
What is the function of this protein?
Plasma membrane reductase that uses cytoplasmic ascorbate as an electron donor to reduce extracellular Fe(3+) into Fe(2+).  Probably functions in dietary iron absorption at the brush border of duodenal enterocytes by producing Fe(2+), the divalent form of iron that can be transported into enterocytes.  It is also able to reduce extracellular monodehydro-L-ascorbate and may be involved in extracellular ascorbate regeneration by erythrocytes in blood.  May also act as a ferrireductase in airway epithelial cells (By similarity).  May also function as a cupric transmembrane reductase (By similarity).
What are the official names of this protein?
Plasma membrane ascorbate-dependent reductase CYBRD1, Cytochrome b reductase 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Localized at the brush border of duodenal cells.
Protein: COX14_YEAST
Sequence: MSKYAWYTRVTDTLHRLTVLTLVGGTLYMSGGLAYTLYMNGKKYEQQVTQQKALEEDNQQLQSPTAPPTE
What is the function of this protein?
Required for the synthesis of yeast cytochrome oxidase.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX14.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: THIE_STRA5
Sequence: MKDTLKLYFVCGTVDCSRKNILTVVEEALQAGITLFQFREKGFTALQGKEKIAMAKQLQILCKQYQVPFIIDDDIDLVELIDADGLHIGQNDLPVDEARRRLPDKIIGLSVSTMDEYQKSQLSVVDYIGIGPFNPTQSKADAKPAVGNRTTKAVREINQDIPIVAIGGITSDFVHDIIESGADGIAVISAISKANHIVDATRQLRYEVEKALVNRQKHSDVIK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RND_HAEIN
Sequence: MSKWDSNIPFLFFSNKKITMIKECQNPPHFRVVTDNTALLEVCNLAQQKSAVALDTEFMRVSTYFPKLGLIQLYDGEHVSLIDPLAITDFSPFVALLANPKVLKILHSCSEDLLVFLQEFDQLPRPMIDTQIMARFLGLGTSAGLAKLAQQYLNVEIDKGATRTNWIKRPLSDIQLQYAAGDVWYLLPLYHILEKELAKTPWEQAVRDDCELVLAKTHKLQERDSEKAYLDIPNAWKLNPLELSRLRVLAQWRQNVAIERDLALSYIVKSEHLWKVAKNNPRNTSEMLEMGLTENEVRVRGKEILQLLSQARRISSNDYPKSIERISEDPRYKKTIRLLQEKVNSLTPEGLTPEIVASKRTLEELIKWVWKYDCSQDKRPELLIGWRKPIGEKLVDALK
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_PROMH
Sequence: MTIRVAINGFGRIGRNVLRALYESGKRAEISVVAINELADATGIAHLLKYDSSHGRFAWDIRVNNDLLQVGDDAIRLFHHADIADLPWGELGIDVVLDCSGVYGSRADGEAHIAQGAKKVLFSHPGTIDLDATVVFGVNQHELKKQHRIVSNASCTTNCIIPIIKMMDDAFGIESGTVTTIHAAMNDQPVIDAYHKDLRRTRAAGQSIIPVDTKLAAGITRIFPKFKDHFEAISVRVPTINVTAIDLSVTVKNAVNVLDVNKLIQKSATGAFRGIVDYTELPLVSTDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAATGFK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SHEPW
Sequence: MANTLEQLKPITTIVADTGDIEAIKRYQPEDATTNPSLILKASQIPEYSDLIENAINWAKSQSDDLEQQIEDAGDKLAVNIGLEILKIVPGRISTEVDARLSFDKTASIAKAHKLIQLYKEAGIDKSRILIKLASTWEGICAAKELEQEGINCNLTLLFSFAQARACAEAGVYLISPFVGRILDWYKKDTGLEYSAAEDPGVVSVTSIYNYYKRHGFNTVVMGASFRNTGEIIELAGCDRLTIGPALLEELSNSNTPIIQKLLPATETIAAQPAMSEAQFRWEFNEDPMAVEKLAEGIRNFAVDQGKLEVMLKAELSS
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_MARMM
Sequence: MTHAPHSEVAQHVAEAAADHADSGVFPPFDPTYFASQLFWLTIAFVILYIALDRLILPKIKTTIEDRRDRIADDLDAAAQAKADAEAAGEAYEKSLAEARNKAHALAAKTRQTLDAEIAKETAAVEAELSAKQEASEAAIRKAKDKAFAEVRGIAATATAAVVSALAGVEVSEADAGKTVDGLIKAKEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RSE1_YEAST
Sequence: MWGGGKMAVVSLSPHTAKMRKLFGQASTTMAYDGLKREAERRTRSDHNITMVAKDDELYLYHLTLKKQTNFVHSCIGHFVDLEAGSKREQSQLCVATETHLELYDTADGELKLIAKFQNLFATITSMKSLDLPHSGSRAKASNWPTFLALTSDSGNLSIVQIIMHAGALRLKTLVNQPLTRTTLRRVSPISYMEIDPNGRCIILSSVEQNKLCFLVDYAQKLRISSPLEIIRPHMVTLDMAVVDVNFNNPCFVTLEIDNAATQLSVHLIFYVLELGLNHIVKKADYLVNPSANFVLSLPDLSRYNITTSLSDNNYDADYDTLFNPFVVIGFENHILVKDMNGFFSLKVEIPKRSITNSRHKNVTIISGIVQKLKNDFFVLLQSNHGDLFKLTVSPDTNDRNRPLVQLSYFDTIQNSHQLHIFKNGYLFALSEMNNNFLFQFEKLGVEKNDFSNVLTSKDPNKSLVFEPSIKLQNLSILSQQLNLNPSIKSQIVSDSPLSIATKHFTNNKIITLTNAVNYSNLISTSLPPNATKLWLIPDPATTGDNNTLLFITFPKKTMILQIDNESMEELTPDEATRSAFKLSQDTTIHTCLMGSHSIIQVCTAELRHIVPTGKSRYSNKLTWVPPAGIRIVCATSSKTQLIISLSNYELVYFKIDVSSDSLIELTTHPELDTMPSKVAIVQDTQHADLLAIADNEGMIKIMSLKDQKEDFLTVISLQLVSEKISDMIMVRDSSIGQLNLHVGLENGVYMKFHIGDVDGSFTDIKRRFLGLKPVSLSYLREISVSLNNEEEEEEEEDDDDEKEEEEINSSGAKWMSCVVCHSSSTWVSYTWKNVWTIRQLKDQNMLSCSKFVNADVAINGVCSISSSGRLNIGRVSNFPTLDNWFHVHESSVNKQENGGGDESNEEEEDEMEEEMEMLQISTFRPRTILSFPNNPKSILFIDNHSGKKQCRISLQIDGECLKFGSSDHLYKILDDIDCVSAAIIDFTRQADHLIICAGDKRLLTYKILVNKDKLSFDIELLHQTEIISPIHAMLKFKNFLLTAMGSTIVLYGLGKKQLLRRSVTQTPVSITKIVSMHQWNYERLAVGDIHESVTLFIWDPAGNVFIPYVDDSVKRHVTVLKFLDEATVIGADRYGNAWTLRSPPECEKIMSNHDPSELSNGAIKYPLDVITLQQKLPNTYDCKFKFQLLNHFFVNDIITDFHILDSLSNSDRPGCIYMGLQGTVGCFIPLLSKGNVFMMGNIENIMAEADDTFYLDYESRKKNNNMRKEDDEEESGSVVLQGRHGIEDEIICEGSCSILGRDHQEYRSYYAPVRKVIDGDLCENFLRLSLNEQEFLAKNLKSVQVEDIIQTINEVRTNYM
What is the function of this protein?
Involved in G2/M transition (By similarity).  Required for pre-mRNA splicing and endoplasmic reticulum (ER) to Golgi secretion pathway.  U2 snRNPs associated protein required for the pre-spliceosome assembly.  The involvement in ER to Golgi secretion is probably indirect and due to the splicing of the pre-mRNA coding for SAR1, a small GTP-binding protein required for COPII vesicle formation from the ER.
What are the official names of this protein?
Pre-mRNA-splicing factor RSE1, RNA splicing and ER to Golgi transport factor 1, Spliceosome-associated protein 130.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTF_BRAOT
Sequence: XVAFETVPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYXLLSAVLDVYEAHLHGYLAGDFVSLADLAHLPFTDYLV
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase, GST class-phi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_ENTDS
Sequence: MGIKGLSKLLARYAPKSMKEGKIDQYSGRVIAIDASILVYQFISAVRDTTGATMVDEFGETTSHIIGTFYRTIKLIESGIKPVYVFDGKPPEMKDGELNKRKENAQKAQEQLDKALEEGDKEQAKKLMKRTARMTKEQSDEVKKLLQLMGIPCVEANCEAEGTCAALVKAGKCYATATEDMDALTLGSEYVVRKFSASDNKKEPIREYSLSSILEETGFSMEQFIDLCILLGCDYCDTIKGVGPITAFELIQQYKSIENVLKHLSDKYKVPENWKYKEARELFLHPDVADFSDYKLEWNKLDEEGIKQYLVTEKHFNEERVTKGIEKLKNVKSKKAQGRLDSFFSVKKVPLSKSEAASGVKRKKPTTKAKESRKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: DUT_ECOSM
Sequence: MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ACCA_YERPA
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDM_CAEEL
Sequence: MSWVRFTKTGVAVVATSAAAVLALDMTNERRFQRQVKDHFRTVHADRLAELNKRAPSALPTRKDILTNLSKGEEFDVLIIGGGATGAGVALDAQTRGLKTALVELDDFSSGTSSRSTKLIHGGVRYLQAAIMKLDLEQYRMVKEALFERHNLLEIAPHLSSPLPIMLPIYKLWQVPYYWSGIKAYDFVSGKRVLKNSFFINKSQALERFPMLRNESLKGALIYYDGQHNDARMNLAIILTAIRHGAACANHVRVEKLNKDETGKVIGAHVRDMVTGGEWDIKAKAVINATGPFTDSIRLMGDPETARPICAPSSGVHITLPGYYSPSNTGLLDPDTSDGRVIFFLPWERMTIAGTTDAPSDVTLSPQPTDHDIEFILQEIRGYLSKDVSVRRGDVMSAWSGLRPLVRDPNKKDTKSLARNHIIEVGKSGLITIAGGKWTTYRHMAEETVDRVVEVHGLKTENGCVTPGLLLEGAHDWNSLQYIHLVQDYGMEVDVAQHLSNTYGDRAFVVARMCKMTGKRWPIVGQRLHPEFPYLDAEVRYAVREYACTAIDVIARRMRLAFLNTYAAHEVLPDVVRVMGQELGWSSAEQRAQLEKARTFIDMEMGQNAKQTAVSNVALNLTKEEMQRAKERFQQLDKDRKGHITVNDLRKHFREHNQKIDERVLHELLNEVDLNKNGEIEIAEFFQLYSGLKGGQLTGNRLVGYLDEIHGTPSVNRACGGI
What are the official names of this protein?
Probable glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EF1B_CANAW
Sequence: MSFSDFSKVESIKSLNEFLADKSYIDGTTATQADVTVYKAFQKEFPQFTRWFNHIASFTEEFEDLPAGKAPAASGSAAAAAEEEDDEDVDLFGSDDEVDEEAEKLKQQRLAEYAAKKAAKGPKPAAKSIVTLDVKPWDDETDLDELLTNVKAIEMEGLTWGAHQWIPVGFGIKKLQINLVVEDALVSLDDLQAAVEEDEDHVQSTDIAAMQKL
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: ATPE_CROS8
Sequence: MAMTYHLDVVSAEKQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEYIYLSGGVLEVQPGNVTVLADTAIRGQDLDEARALEAKRKAEDHIRSSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HED1_YEAST
Sequence: MQQRSNRRSCSYIPLGVHNNAEKSLCTEVAPARKNKRSITTSPIVNINVVERRLFNLELEKQQLRAKNLSENTGGGSPNGGAYLDAKKGVREQDQYQGGPSKELDRLQPPPSMKKSPPRKKKSLKDLIYETNKTFYQVDSNKVKYKVGLSKKQLLPSKTVDN
What is the function of this protein?
Involved in regulation of meiotic recombination and repair of DNA damage.  Inhibits RAD51-mediated recombination when the meiotic recombination machinery is impaired.
What are the official names of this protein?
Meiosis-specific protein HED1, RED1 suppressor protein 1.
Protein: TPC1_ARATH
Sequence: MEDPLIGRDSLGGGGTDRVRRSEAITHGTPFQKAAALVDLAEDGIGLPVEILDQSSFGESARYYFIFTRLDLIWSLNYFALLFLNFFEQPLWCEKNPKPSCKDRDYYYLGELPYLTNAESIIYEVITLAILLVHTFFPISYEGSRIFWTSRLNLVKVACVVILFVDVLVDFLYLSPLAFDFLPFRIAPYVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLLFASWIAFVMFEDTQQGLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAVVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQIYHSALSQQLRAFVRSPNFGYAISFILIINFIAVVVETTLDIEESSAQKPWQVAEFVFGWIYVLEMALKIYTYGFENYWREGANRFDFLVTWVIVIGETATFITPDENTFFSNGEWIRYLLLARMLRLIRLLMNVQRYRAFIATFITLIPSLMPYLGTIFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLEEEEKCQGQDSQEKRNRRRSAGSKSRSQRVDTLLHHMLGDELSKPECSTSDT
What is the function of this protein?
Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane.  Is one of the essential components of the slow vacuolar (SV) channel.  Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition.  Involved in the regulation of germination and stomatal movement.
What are the official names of this protein?
Two pore calcium channel protein 1, Calcium channel protein 1, AtCCH1, Fatty acid oxygenation up-regulated protein 2, Voltage-dependent calcium channel protein TPC1, AtTPC1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.
Protein: EI01_LITRU
Sequence: FVPIWM
What are the official names of this protein?
Electrin-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMH_STRSE
Sequence: MTKEFNHTTVLLHETVDMLDIKPNGIYVDATLGGAGHSEYLLSQLTDGGHLYAFDQDQTAIDHAHIRLASYIEKGQVTFIRDNFRNLKTRLAELGVTEIDGICYDLGVSSPQLDERERGFSYKQDAPLDMRMNREGHLTAYDVVNNYDYHDLVRIFFKYGEDKFSKQIARKIEQARAVKPIETTTELAELIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAIDLLALDGRISVITFHSLEDRLTKQLFKEASTIDVPKGLPFIPDDLKAPLELVNRKPILPSQEELEANNRAHSAKLRVAKKVHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_LEPBL
Sequence: MEKLLERVNHILEALPYITKYSGKTVVIKYGGAAMAKADLKESFAKDIVLLKYVGIHPVIVHGGGPEINRLLDSLKIPTEFIHGHRVTDTQTMEVVEMVLTGKVNKQIVSMINSQGGKAVGISGKDGNLAKAVKAPIEIELEGKEKQLFDVGLVGRIESINPEILHNLQKEGFIPVISPVAESVEGDSLNINADTFAGEIAGALEAEKLILLTDTEGILIDGKLATGLSRGKMKEYIRKGEISGGMIPKVECCLAAIDQGVNRTHIIDGRVSHSILIEIFTNQGIGSLIES
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAD12_MOUSE
Sequence: MLTRNSLYLLLWILFDGGLLTPLQPQPQQTLATEPKENVIHLSGRRSHFQRVKRGWVWNQFFVLEEYMGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVASVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTVVNITLTDVNDNPPRFPKSIFHLKVPESSPVGSAIGRIRAVDPDFGKNAEIEYNIVPGDGGNLFDIVTDEDTQEGIIKLKKPLDFETKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTAQDLDVGSSAVRYFIDWKSDGESYFTIDGTEGTIATNELLDRENMAQYNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQIVGAVDRDLSPAGQQFSFRLAPEAVIKPNFTVHDFRNNTAGIETRRNGYSRRQQELYFLPIVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCMVILLAIVVLYVALRRQRKKDTLMTSKEDIRDNVIHYDDEGGGEEDTQAFDIGALRNPKVIEENKIRRDIKPDSLCLSRQRPQVEDNTDIRDFIHRRLQENDADPAAPPYDSLATYAYEGNGSVAESLSSIDSLTTEADQDYDYLSDWGPRFKVLADMFGEEESYNPDNVT
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).
What are the official names of this protein?
Cadherin-12.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MURA_RICAE
Sequence: MHKLIIHGGTPLKGSINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGADIEIIEHQDEFELIIDTKNINNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGAEIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLAEGETVLFNCGREPEIVDLCNCLITMGADIAGIGTSEITIKGKDSLNKASYKVLSDRIEAGTYMFAAAITKGDVKICRIDYHIVKNIALKLIETGIKVVPINNGVQVTYEGKLNSVDLETNPYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTSSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARREH_SYNY3
Sequence: MTDFNHPPRILFLYGSLRERSYSRLLAEEAGRIITTMGAETKFFDPRELPLRGQVLDSHPKVQELLELSQWSEGQVWSSPEMHGNITGILKNQIDWIPLEIGSIRPTQGRTLAVMQVSGGSQSFNAVNTMRILGRWMRMFTIPNQSSVAKAYQEFHEDGTMKDSPYRDRVVDVMEELYKFTLLLRDKVDYLTDRHSERKAKVNTDG
What is the function of this protein?
Has high NADPH-dependent quinone reductase activity with a preference for quinones with hydrophobic substituents.  Reduces also CrO4(2-) and Fe(3+).  Somewhat active with NADH.  May be involved in response to oxidative stress caused by arsenic.
What are the official names of this protein?
NADPH-dependent quinone reductase ArsH, Arsenical resistance operon protein ArsH.
What is the protein family that this protein belongs to?
Belongs to the ArsH family.
Protein: GPMA_HYPNA
Sequence: MTKLALIRHGQSAWNLENRFTGWWDADLTAQGEAEARHSGKLLAEVDADFRAGFTSVQTRAIRTMWLALTEMKRVWLPIEKDWHLNERHYGGLTGLNKAETAAKHGEDQVHVWRRSYDIPPPPLEVGSTFDLSTDPRYRGIDIPNTESLKTTLDRVLPYWQQKIAPGLIAGTDTMIAAHGNSLRALVKHLFNVPDETITGLEIPTGNPLLIELDPNLKPVSVRYLDAERAHSLPDLP
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MDHC_BOVIN
Sequence: MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFITTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYGIPDDLLYSFPVTIKDKTWKVVEGLPINDFSREKMDLTAKELAEEKETAFEFLASA
What is the function of this protein?
Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH.  Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation.
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic, Aromatic alpha-keto acid reductase, KAR, Cytosolic malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLB_ECODH
Sequence: MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.