PharMolix/UniProtQA huggingface dataset:
Protein: REP_PYMVV
Sequence: MPRKGSFSIKAKNYFLTYPQCSISKEEALSQLQNLTIPVNKKFIKICRELHENGEPHLHVLIQFEGKYNCTNNRLFDLVSPTRSTHFHPNIQGAKSSSDVKSYVEKDGDTIEWGLFQIDGRSARGGQQTVNDAAAEALNSGTKEAAMKIIKEKLPEKFLFQYHNLSCNLDRIFMKAPETWAPPFPLSSFTNVPDEMQEWADGYFGKSSAARPERPISIIIEGDSRRGKTMWARVLGPHNYLSGHLDFNPRVYSNEVEYNVIDDVAPQYLKLKHWKELLGAQRDWQSNCKYGKPVQIKGGIPSIVLCNPGEGSSYKAFLDKDENASLKNWTLKNAVFITITAPLYQEGTQASKEEGNQEETH
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TRPD_ENDTX
Sequence: MIREAIYEIVNRNNLTIDKTKEVMNRIMDGGATDAQIASFLTSLRLKGETIEEITACAMVMREKCQKLNPEFDVLDIVGTGGDELATFNISTISSFIIAAAGVPVAKHGNRSVSSKCGSADLLEVLGVNIMLTPQQCEAILKKVGMCFLMAQTFHSSMKYVAKVRKELGIRTIFNILGPLANPAKASYELIGVYDENLVEPIASVLVNLGVKRAMVVHGHDGLDEITLSDTTTICEVNRGRLNSFFITPEQFGLKRCSLSELIGGTPQENREIALNILNGEQGAKRDTVVLNSAVCLYMFYDNMTLKQCLRMAQDMIDSKKALNKLDEFIKASHET
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: DAPB_NITEC
Sequence: MTLLNIAVAGSTGRMGRTIMETIADAQDLRLSAALEQPDSPYLSQDAGGLTGTPCGVIINSDYASALTGSDVLIDFTRPAGTLTHLAVCRQSGIHMVIGTTGFSAEEKEIIHDAAKDIAIVFAPNMSVGVNILFRLLEVAAKALPAGYDVEIIEAHHRHKVDAPSGTALRMGEVIAQTQGKNLEKVAIYGREGHTGERAADTIGFSTIRGGDIVGDHTALFAGIGERLEITHKASSRKTFATGALHAARFLATKKSGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_BURO1
Sequence: MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELDAAHKRVDQELAQARNDGQQRIADAEKRAQAVAEEIKANAQAEAARIVAQAKAEAEQQIVKAREALRGEVAALAVKGAEQILKREVDQTAHAQLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
Protein: CLPS_PSEP1
Sequence: MHAPSEIRLTFNQDRPQSNEDDGSGLAVQEAKPILQAPPMYKVVLFNDDYTPMDFVVEVLETFFSLNRELATKIMLTVHTEGRAVCGLFTRDIAETKAMQVNQYARESQHPLLCEIEKDG
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: SECR_PIG
Sequence: MATRALLLLLLLPPLLLLAGCAARPAPPRAPRHSDGTFTSELSRLRDSARLQRLLQGLVGKRSQQDPENNTAWTKSGEDRLCQLWSHMPALQAWMPMKPPVDQAWSPWLPPGLRAGALVSEPAIPAAEGSPMPP
What is the function of this protein?
Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis.  Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells.  Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content.  Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity).  Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid.  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation.  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation.  Also able to stimulate lipolysis in white adipocytes (By similarity).  Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (By similarity).  Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (By similarity).
What are the official names of this protein?
Secretin.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOD_MAGMM
Sequence: MPATITDHKEFQNYAINFGPQHPAAHGVLRLLLELDGEVVERADPHVGLLHRGTEKLLEQKTYIQGTPYFDRLDYMSMMSEEHAWVIAVERLGQIEVPERAQYIRTIYAEITRFINHLLFFAAHGLDVGAMTMFLYCFREREELMDIYEAACGARMHANYFRPGGVARDLPDGLEQRIRDFCNHFPSKLDEYETLLTNNRIWKQRLVDIGKVSQEDAFSWGFTGPMLRGSGVAFDLRKAEPYDAYDRVEFDIPVGKNGDSYDRYLVRIEECREGVKIIQQCLDQMQPGPVRNDNFKISMPYRQDMQQDMESMIHHFKLCTEGFNLPAGEVYAAVETPKGELGVYLVSDGGNKPYRARIRAAGFNHLQAVKEMARGHMIADVTTIIGSIDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLPX_AGRVS
Sequence: MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKILDEYVIGQRQAKKILSVAVHNHYKRLSHASKGGDVELAKSNILLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISARGEKTSIGFGATVVSPEDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDALIQILSEPKNALVKQYQRLFEMEDVELSFHEDALREIARKAITRKTGARGLRSIMEKILLDTMFELPELEGVREVVISDEVVRGAARPLYIYADRQEEKANASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PNC1_SOYBN
Sequence: MNVDLESLAEATSGAIGSLISTTILYPLDTCKTKYQAEARSSGRTKYRNLTDVLLEAISNRQVLSLYQGLGTKNLQSFISQFVYFYGYSYFKRLYLEKSGYKSIGTKANLVIAAAAGACTAIATQPLDTASSRMQTSEFGKSKGLLKTLTEGNWSDAFDGLSISLLLTSNPAIQYTVFDQLKQRALKNKQDNADKGTSPASLSAFMAFLLGAISKSIATCLTYPAIRCKVIIQAADSAEETSKTKIKSQKTVLSVLYGIWKREGILGYFKGLHAQILKTVLSSALLLMIKEKISASTWVLILALKRYLLLPRGKVKNL
What is the function of this protein?
Peroxisomal adenine nucleotide transporter catalyzing the counterexchange of ATP with AMP.  ATP is needed by reactions that generate acyl-CoA for peroxisomal fatty acid beta-oxidation during postgerminative growth.  Required for the conversion of seed-reserved triacylglycerols into sucrose that is necessary for growth before the onset of photosynthesis.
What are the official names of this protein?
Peroxisomal adenine nucleotide carrier 1, GmPNC1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ATPI_NASOF
Sequence: MNVLSCSINTLIKEGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSAVLAIRNPQTIPTDGQNFFEFVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPQGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NUOD_BACAH
Sequence: MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICHAVETMIGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYNRFDFDIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRAP1_MOUSE
Sequence: MACELRAVLLWGRGLQTVLRAPALAGVRRGKPVLHLQKTTVQFRGPTQSLASGISAGQLYSTQAAEDKEEESLHSIISNTEAVRGSVSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVCEGQVLPEMEIHLQTDAKKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLEALQNQAETSSKIIGQFGVGFYSAFMVADKVEVYSRSAAPESPGYQWLSDGSGVFEIAEASGVRPGTKIIIHLKSDCKDFASESRVQDVVTKYSNFVSFPLYLNGKRINTLQAIWMMDPKDISEFQHEEFYRYIAQAYDKPRFTLHYKTDAPLNIRSIFYVPEMKPSMFDVSRELGSSVALYSRKVLIQTKAADILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTTAEQDIKEDIAKLLRYESSALPAGQLTSLPDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKQKHTEVLFCYEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDTSPADERLSEKETEDLMAWMRNALGSRVTNVKVTFRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHTLIKKLCQLRESEPELAQLLVDQIYENAMIAAGLVDDPRAMVGRLNDLLVKVLEKH
What is the function of this protein?
Chaperone that expresses an ATPase activity.  Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I.  Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis.  The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
What are the official names of this protein?
Heat shock protein 75 kDa, mitochondrial, HSP 75, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix.
Protein: Y2062_YERPS
Sequence: MLCAIYRSPKRDQTYLYIEKKDDFSRVPAELLASFGKPQFAMLLALNERKTLATADVEKVKNALIEQGFYLQVPPPPESLLKMHLGETKA
What are the official names of this protein?
YcgL domain-containing protein YPTB2062.
Protein: TX31B_SCOMU
Sequence: MKPSMAILLVIALIIFSLDKSYSANDKPIGKCGDAKRNKPCLACSHRSSIADFYSKCCTYDAVYNGCLDKLRH
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Kappa-scoloptoxin(03)-Ssm1b, Kappa-SLPTX(03)-Ssm1b, Kappa-scoloptoxin-Ssm1b, Kappa-SLPTX-Ssm1b.
What are the subcellular locations of this protein?
Secreted.
Protein: VKTB1_DABSI
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPKFCYLPADPGECLAHMRSFYYDSESKKCKEFIYGGCHGNANKFPSRDKCRQTCGGK
What is the function of this protein?
Serine protease inhibitor that has activity against chymotrypsin (Ki=4. 77 nM) but not against trypsin.
What are the official names of this protein?
Kunitz-type serine protease inhibitor B1, BBPTI-1, BPTI-1, Trypsin inhibitor 1, Trypsin inhibitor B1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: WNT2_DASNO
Sequence: MNAPLGGIWLWLPLLLTWLTPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSKGTFDWGGCSDNIDHGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWAVPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RS12_PSEFS
Sequence: MATINQLVRQPRKRIVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKGRNQGRSKYGTKKPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MURG_MYCA1
Sequence: MNDTVKKPTGGRGDDPLPAGAALSAVAPHEPVSVVLAGGGTAGHVEPAMAVADALKALDPNVRITSLGTARGLETRLVPERGYDLELITPVPLPRKPTGDLARLPSRVWRAVRETRAVLHAVDADVVIGFGGYVALPAYLAARGVSPRKPRVPVVIHEANASAGLANRVGARTAQRVLSAVADCGLPGAEVVGVPVREAITSLDRAAVRAEARRHFGFADDARVLLVFGGSQGAASLNRAVSGAAAQLAAAGVSVLHAHGPKNTLDLREPQPGDPPYVAVPYLDRMDLAYAAADLVICRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPVVNAGGGMVVADADLTPELVAREVAGLVGDPPRLAAMTTAAARVGHPDAARRVAQAALDIGRTARRARGATGGRP
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATG23_KLULA
Sequence: MDLNDLLLQQQEVTNLLSNLQEAHKRILISNEDENNDLNKIRKDILICLNDLKTVNSLIIDPRDGLIKKNLHKLEKYEQELRSLESEEAAIESNLNQWKIDQDPENVRRKENWGTVPINLVGNHQYLLESYVNEVGIENTTLANTNGNHEETPNSSKFTREQLLRNARKLKLCQEQVNSEIDQLKSLISQYERDRNVINDEYNRTTELIQKEVNTLSREEDKINSQREKILKKLGLLKDHEQNQPRNFFFSLGALARVDNSDFKIALSQAYEFIDAKKQALKKILHENKSQTMSLEHNFSIWNDVIRSIQGLETNLQQSFIEKEGNVPKTDITSMISRTLSRVNSIVGTYSKDSIFTSILCELKALQKALDELNGKMQPIPIKSSAKTPELLQMGKSPPKVALSKEYASNLHESTEDFPLKINKTD
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.  Also plays a role in regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 23.
What is the protein family that this protein belongs to?
Belongs to the ATG23 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: BIP_CORAV
Sequence: MAGSWRARGSLVVLAILLFGCLFAISIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFTDGERLIGEAAKNQAAVNPERTIFDVKRLIGRKFEDKEVQKDMKLVPYKIVNKDGKPYIQVKIKDGETKVFSPEEISAMILIKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGIIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDMRIMEYFIKLIKKKHGKDISKDNRAIGKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDFVQKDHGTREEAMEDAGLAKNQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGSILSGEGGEETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRNLGKFDLTGVPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIDRMVQEAEEFAEEDKKVKERIDARNTLETYVYNMKNQVNDKDKLADKLESDEKDKIESAVKDALEWLDDNQSAEKEDYDEKLKEVEAVCNPIITAVYQRSGGAPGGGSGEEDEDSESHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein homolog, GRP-78 homolog, Binding-immunoglobulin protein, BiP, Heat shock protein 70 family protein, HSP70 family protein, Luminal-binding protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: P33MX_XENLA
Sequence: MASRQPDVPAIEHGSSGLLGKMSLPVGMHRRAFSYDDALDDTAPMTPPPSDMCSNTMWRKPIIPERKYQLLSKIEDGDSNIPPPSLPPSSSTEKVPVVKAKATSIIMNSLMTKHTQESIQRFEQQAGLRDAGYTPHKGLTSEETKYHRVAEALHKLNMHIGESTEEKQSSSAQSTPCSTPSSSPKQMRRSWFSQGSTSSLPAGDLSNSDGGVDKWSMFGPRAVQKSTTDPGGFTVQPYKGAQKPTPMELMRAQASRISDDPAALKPPKMEMPSLVSGTKNIPRGHNLKPRDMNILTPTGF
What is the function of this protein?
Potential NADPH-dependent oxidoreductase.
What are the official names of this protein?
Putative monooxygenase p33MONOX.
What is the protein family that this protein belongs to?
Belongs to the P33MONOX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_BURPS
Sequence: MSNEAKCPFHQAAGNGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGELKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  Also displays NADH oxidase, isoniazid hydrazine lyase and isonicotinoyl-NAD synthase activities.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL1_PYRAB
Sequence: MSRMPFDRQKIVEAVKEAKARAKPRNFTQSVEVAVNLKDIDLKRPENRFKLEVVLPHGRGKDVKIAVIADGAVAEAARRLGLDVISSAELEEIAQSPRQARKLAKKYDFFIAEAPLMPKIGRYLGKYLGPRNKMPVVVPPTMSNLEPIVEKLKKTVRIQLKNNPVVHAPVGTEKMSDEEIAENIETVLNAIIGKLERGESQIKSVYVKTTMGPAVKVKG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PLAS_ANAVA
Sequence: ETYTVKLGSDKGLLVFEPAKLTIKPGDTVEFLNNKVPPHNVVFDAALNPAKSADLAKSLSHKQLLMSPGQSTSTTFPADAPAGEYTFYCEPHRGAGMVGKITVAG
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface (PubMed:8679527).
Protein: IFNB_FELCA
Sequence: MTGRCILQIALLVCFFTTAHSVSYKLLGFQLRSSSLECQELLVNLNRTSKYCLKDRMNFEVPEEIKKSQRFQKEEAILVINEMFQKIFNIFSRSTSSTGWNETTVENLLATLHWQKEHLETILEEIMEEENFTWDNTTLLNLKKYYLRIVRYLKAKEYSVCAWTVVHAEILRNFFFLERLTDYLQN
What is the function of this protein?
Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli.  Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins (By similarity).  Signals mostly via binding to a IFNAR1-IFNAR2 heterodimeric receptor, but can also function with IFNAR1 alone and independently of Jak-STAT pathways.  Elicits a wide variety of responses, including antiviral and antibacterial activities, and can regulate the development of B-cells, myelopoiesis and lipopolysaccharide (LPS)-inducible production of tumor necrosis factor.  Plays a role in neuronal homeostasis by regulating dopamine turnover and protecting dopaminergic neurons: acts by promoting neuronal autophagy and alpha-synuclein clearance, thereby preventing dopaminergic neuron loss.  IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity).
What are the official names of this protein?
Interferon beta, IFN-beta.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.