PharMolix/UniProtQA huggingface dataset:
Protein: RSBV_BACSU
Sequence: MNINVDVKQNENDIQVNIAGEIDVYSAPVLREKLVPLAEQGADLRICLKDVSYMDSTGLGVFVGTFKMVKKQGGSLKLENLSERLIRLFDITGLKDIIDISAKSEGGVQ
What is the function of this protein?
Positive regulator of sigma-B activity.  Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B.  When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.
What are the official names of this protein?
Anti-sigma-B factor antagonist, Anti-anti-sigma-B factor.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: ACDH2_DECAR
Sequence: MTQKIKCALIGPGNIGTDLLYKLKRSPFLEPVWMIGIDPESEGLKRATDMGLKTCATGVDGFLPHVLEDNVQIAFDATSAYVHAENSRKLNALGVLMIDLTPAAIGPFCVPPVNLKEHVGRREMNVNMVTCGGQATIPMVAAVSRVQPVAYGEIVATVSSKSAGPGTRKNIDEFTRTTAGAVEKVGGAKKGKAIIIINPAEPPLVMRDTVHCLTETAPDQAAITESIHAMIKEVQKYVPGYRLVNGPVFDGNRVSVYMEVTGLGDFLPTYAGNLDIMTAAGARTAEMFAEEMIKGTLKLEPVHA
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase [acetylating] 2.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: METE_YERPN
Sequence: MTILNHTLGFPRVGLKRELKKAQESYWAGNSTQEELLNVGRELRARHWQQQQQAGVDLVPVGDFAWYDHVLTTSLLLGNVPERHQNADGSIDIDTLFRIGRGRAPTGKPAAAAEMTKWFNTNYHYMVPEFQQGQQFKLGWTQLLDEVDEALALGHKIKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQEWLDAYQPAYQALQGQVKLLLTTYFDSIGHNIDTIRALPVQGLHVDVVTGHDDLAVLNKNLPKEWLLSLGVINGRNVWRADLSSWFERLQPLVNSRPLWLGSSCSLLHSPIDLNEETRLDAEVKSWFAFALQKCAELALLTQALNAPNDAKLAELAAYSAPIRARRSSSRVHNAQVEQRLAAITSQDIERQLPYEARAETQRKRFNLPAWPTTTIGSFPQTTEIRGLRLDFKQGRLDGKNYRTGISEHIKHAIAEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVIIGDISRPEAITVEWAKYAQSLTEKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVEDLEKAGIGIIQIDEPALREGLPLRRADWQAYLQWAVDAFKLNAAVAQNDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEDFAYPNEIGPGVYDIHSPNVPSVEWIEALLRKAAQRIPAERLWVNPDCGLKTRGWPETRQALANMVLAAQRLREEQV
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: YI177_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSTFLERFHNNRIVFCLPFFLALFFVPVQKVLQHLCLRFTQVAPYFKIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YJL225W-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OSTN_HUMAN
Sequence: MLDWRLASAHFILAVTLTLWSSGKVLSVDVTTTEAFDSGVIDVQSTPTVREEKSATDLTAKLLLLDELVSLENDVIETKKKRSFSGFGSPLDRLSAGSVDHKGKQRKVVDHPKRRFGIPMDRIGRNRLSNSRG
What is the function of this protein?
Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782).  Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782).  Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
What are the official names of this protein?
Osteocrin, Musclin.
What is the protein family that this protein belongs to?
Belongs to the Osteocrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK22_ANGEV
Sequence: MGTDNKSKVEARASARYFKMSANKARRVINQIRGRSYEQALILLEFMPYRACYAILQLISSAAANANHNLGLSRANPFISEAKVDESTLFKRFQPRAQGRGYPIHKPTCHITITMIEKT
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFP_JANMA
Sequence: MKPAKEIRVGNIIMVDSKPMIVLRSDVNGSSRTGFTYKWKMKNLLTNTPMENVFRGDDKFDVVVLDKKPVTYSYFADPLYVFMDEEYNQYEIEEENLGDALHYLKDGMECEAVFYDGKAISVELPITIARQVVYSEPAVKGNTSGNVLKEAKIENAVEAHRHTVQVPLFVSQDDVIEIDTRTNEYKRVVRN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z585B_PONAB
Sequence: MPASWTSPQKSSALAPDDHGSSYEGSVSFRDVVINFSREEWQHLDLSQRNLYRDVMLETYSHLLSVGYQVPKPEVVMLEQGKEPWALQGERPRHSCPGEKLWDHNQHRKIIGYKPASSQDQKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLYVCIECGRAFVQKPEFITHQKAHMREKPYKCNECGKSVFQVSSLFRHQRIHTGEKLYQCSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQRSTLKMHQKIHTGERSYICIECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLEVHQRIHTRLKPYICTEYGKVFSNNSNLITHEKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYACSDCGKAFTQKSTLTVHQRIHTGEKSYVCMKCGLAFIRKAHLVTHQIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSDLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPLHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFSNRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQGSHA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 585B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LRP8_MOUSE
Sequence: MGRPELGALRPLALLLLLLLQLQHLSAADPLPGGQGPVKECEEDQFRCRNERCIPLVWRCDEDNDCSDNSDEDDCPKRTCADSDFTCDNGHCIPERWKCDGEEECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTLCAPHEFQCSNRSCLASVFVCDGDDDCGDGSDERGCSDPACPPREFRCGGGGTCIPERWVCDRQFDCEDRSDEAAELCGRAGQGTTATPAACAPTAQFTCRSGECIHLGWRCDGDRDCKDKSDEADCSPGPCRENEFQCGDGTCVLAIKRCNQERDCPDGSDEAGCLQESTCEGPRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCKAVAGKSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVATNRIYWCDLSYRKIYSAHMDKASIPDEQVVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATTDGRRRCTLFSRELSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDKVFWTDLENEAIFSANRLNGLEIAILAENLNNPHDIVIFHELKQPKAADACDLSAQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPQSTSTTTLASAMTRTVPATTRAPGTTIHDPTYQNHSTETPSQTAAAPHSVNVPRAPSTSPSTPSPATSNHSQHYGNEGSQMGSTVTAAVIGVIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEEEDELHIGRTAQIGHVYPAAISNYDRPLWAEPCLGETRDLEDPAPALKELFVLPGEPRSQLHQLPKNPLSELPVVKCKRVALSLEDDGLP
What is the function of this protein?
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands.  LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail.  Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons.  LRP8 has higher affinity for Reelin than VLDLR.  LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development.  Binds the endoplasmic reticulum resident receptor-associated protein (RAP).  Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature.  Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation (PubMed:12695510).  May also function as an endocytic receptor.  Not required for endocytic uptake of SEPP1 in the kidney which is mediated by LRP2 (PubMed:18174160).  Together with its ligand, apolipoprotein E (apoE), may indirectly play a role in the suppression of the innate immune response by controlling the survival of myeloid-derived suppressor cells (PubMed:29336888).
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 8, LRP-8, Apolipoprotein E receptor 2.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Isoforms that contain the exon coding for a furin-type cleavage site are proteolytically processed, leading to a secreted receptor fragment.
Protein: DHE3_VITVI
Sequence: MNALAATNRNFRHASRILGLDSKLEKSLLIPFREIKVECTIPKDDGSLATYVGFRVQHDNARGPMKGGIRYHPEVDPDEVNALAQLMTWKTAVVDIPYGGAKGGIGCTPKDLSMSELERLTRVFTQKIHDLIGTHTDVPAPDMGTNAQTMAWILDEYSKFHGHSPAVVTGKPIALGGSLGREAATGRGVVFATEALLAQHGKSIKGLTFVIQGFGNVGSWVARLIGERGGKIIAVSDVTGAVKNQNGLDIVDLLRHKEETGCLTNFSGGDHMDPNELLTHECDVLIPCALGGVLNKENAADVKAKFIIEAANHPTDPEADEILSKKGGVILPDIYANAGGVTVSYFEWVQNIQGFMWEEEKVNNELQKYMTKAFHNIKAMCQSHNCSLRMGAFTLAVNRVACATTLRGWEA
What are the official names of this protein?
Glutamate dehydrogenase, GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: MG43_TARMA
Sequence: VKRPMNAFMVWSQNERRKIMDQWPDMHNAEISERLGRRWQLLQDSEKIPFVKEAGRLRLKHMADYPDYKYRP
What are the official names of this protein?
SRY-related protein MG43.
What are the subcellular locations of this protein?
Nucleus.
Protein: KMO_NEUCR
Sequence: MEERKQKVVVVGAGPVGSLAALYAANRGHDVEIYELRGDLRDPSTTPLNFTRSINLALSERGLNAMRHANQPRLIDYVKGVTIPMRGRMIHGKRPDGKLYEEAQDYDIHGRSILAIDRGDLNKRLLDMLEEMPNVTFFFNHKLTGADFKRNKAWFENKDESTSNPRDRAREIEVDFDFMIGADGAHSAVRYHLMKFSRMDYQQEYIDTLWCEFQIAPSSSSAKSKFRISPNHLHIWPGKEFMFIAIPSNDGSFTCTLFAPAAIYEQLEEAGRTGDTSSSIPEFFDMHFPGVTSLIAPADLIAQFQTNPHLPLISIKCKPYHFSSSVVIVGDAAHAMVPFYGQGMNAGLEDVRILFDILDKHDRMTNDDSSLEASQRELALAEYSAVRVADAHAINDLALQNYIEMRSSVLSPVYRWRKALEEWLSVYVPSLGWQTKYSRVSFGNERYSEVVKKSERQGQVLLRSLVGGVGLPMLAGGLFLWFRYKGALGRAAYGVFYNCMGMVCRTIHGRRR
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Biosynthesis of nicotinic acid protein 4, Kynurenine 3-hydroxylase, Nicotinic acid-requiring protein 3.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL18_HAEI8
Sequence: MDKKSARIRRAARARHMMREQGVTRLVIHRTPRHIYAQVIAPNGSEVLAAASTVEKAIREQVKYTGNKDAAAAVGKAVAERALAKGVQAVAFDRSGFKYHGRVQTLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HDAH_PSEAE
Sequence: MTRRTAFFFDELCLWHAAGPHALTLPVGGWVQPPAAAGHAESPETKRRLKSLLDVSGLTARLQLRSAPPASDEDLLRVHPAHYLERFKALSDAGGGSLGQDAPIGPGSYEIARLSAGLAIAALDAVLAGEADNAYSLSRPPGHHCLPDQAMGFCFFANIAVAIEAAKARHGVERVAVLDWDVHHGNGTQAIYYRRDDVLSISLHQDGCFPPGYSGAEDIGEDRGRGFNLNVPLLPGGGHDAYMQAMQRIVLPALERFRPQLIVVASGFDANAVDPLARMQLHSDSFRAMTAMVRDAAERHAGGRLVVVHEGGYSEAYVPFCGLAVIEELSGVRSAVRDPLRDFIELQQPNAAFRDFQRQRLEELAAQFGLCPAQPLQAAR
What is the function of this protein?
Probable protein deacetylase that catalyzes deacetylation of acetylated lysine residues.  In vitro, exhibits high activity against artificial HDAC (histone deacetylase) substrates containing acetylated and trifluoroacetylated lysine residues.  Is not able to deacetylate acetylated polyamines.
What are the official names of this protein?
Histone deacetylase-like amidohydrolase, HDAH, Acetylated lysine deacetylase, Histone deacetylase homolog PA3774.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
Protein: KLF15_MOUSE
Sequence: MVDHLLPVDETFSSPKCSVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGGSGGIGDSSGPVTWGSWRRASVPVKEEHFCFPEFLSGDTDDVSRPFQPTLEEIEEFLEENMEAEVKEAPENGSRDLETCSQLSAGSHRSHLHPESAGRERCTPPPGGTSGGGAQSAGEGPAHDGPVPVLLQIQPVAVKQEAGTGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLPSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN
What is the function of this protein?
Transcriptional regulator that binds to the GA element of the CLCNKA promoter (By similarity).  Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart.  Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis.  Is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A, GATA4 and MYOCD activity.  Is a negative regulator of TP53 acetylation.  Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation (By similarity).  Involved in podocyte differentiation.
What are the official names of this protein?
Krueppel-like factor 15, Cardiovascular Krueppel-like factor.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOC3_SCHPO
Sequence: MNPYVSYPEIHMKRNRTGSINSNPLYIPNPNVEPTPKPTKRRTKTGCLTCRRRRIKCDETKPFCLNCTKTNRECEGYPNSAAQMQAMGSVSPPELSVHSAQQPLIPTSIASSSAQTGDTFSGSSQSNFNTNDLNQMTSSSNLSTVTPIKQDHQKPMNLQGFPSAYQQHQYLQSNHNVPTNNSSSATSSTKPSVQSVGQASYPFLSSVSNFPSNFNSELFPFYFHDVVPSICAFEFDNNIALHFWSVTVPQFAQSMPCIANSLMAFASIKKLDVFGAYSHLTRALRCPMPGPNSFEYLLVSAFLTLTQLNLPAYDLNFCNNFIRKLSWSSSTKSNYVSLLIAMVVRELVFAILPRGCIWGFNGKPLSEVSVSRSHAPVSDSLFTIGLDILSQPTLSDDLHRERMVAWRDEYHVHLYSASRSPLTKVIDCVGHAVTKNNNDVLSGLQQLMQEECTDIAVLRTSYLCVLSLQNVFASNSKEFKLRAQIESHFGRLMLEHFMDCNVLNRPVL
What is the function of this protein?
Induces sexual development and ascus formation.  Also involved in calcium homeostasis.
What are the official names of this protein?
Transcriptional regulatory protein moc3, Multicopy suppressor of overexpressed cyr1 protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYL_SYNAS
Sequence: MNRKYVPQEIEEKWQRYWEEKNTFKVTEDPSKKKYYLLEMFPYPSGKIHIGHVRNYTIGDVVARYKRMEGYNVLHPMGWDSFGMPAENAAIERGIHPSLWTNENITHMRKQLKRMGFSYDWDREVSTCEPVYYRWEQLFFLWMYEKGLAYKKTSSVNWCPRCQTVLANEQVEAGLCWRCGSEVVEKILDQWFFRITAYIDELLAGCDRLTGWPERVLTMQRNWIGKSYGCEVSFPMADGNGDIKVFTTRQDTLFGATFMLIAAEHPLVMELIKGKPVEKDARTFAEEVKKQDKLMRTSDYYEKQGLFLDCYCLNPLTGWEMPIFATNFVLADYGTGCVMAVPTHDQRDFEFAEKFGLRKVVVISPPDKTLDPETMTEAYVEEGILVNSGPFNGMENLKALDAIADHLIALGRGKRTIQYRLRDWGISRQRYWGAPIPMIMCPKCGTVPVPEAELPVVLPRDVDFSGEGGSPLAKHPEFLNTTCPSCGGPAKRESDTMDTFVESSWYFERYCCPHFAEKPGLNRQQVDYWMPVDQYIGGIEHAILHLLYARFYTRMLRDFGLVGVDEPFTNLLTQGMVCKETTRCPDHGYLYPEEVREGRCIHCLAEVIVGKTEKMSKSLKNVVDPDYLVRQYGADTARMFCLFAAPPEKDLEWSDQGVEGSFRFIGRTWRIVVDYLDDLQGIAPFAGDGELEGELKSLRRKTHQTIRKVRDDMGERFHFNTAISAIMELVNTLYGLPRPPREDRTALAVIRETIEAIILLLAPIVPHLTEELWQMLGHQGTCLADTPLPVYDPTVAAEDEMTIVIQVNGKVRSRVIVAADEAEDKIKALAMGDEKVSRFLEGKSVIKQVYVPKKLVNIVVKG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_CERSK
Sequence: MDGCGTYLDTMRREAPLVQCITNFVAMNVVANVLLAAGASPAMVHDAEESGEFAAIAQALTINMGTPSPRWVEGMEAAARGATAAGRPWVLDPVAVGATAFRRGLGARLLALKPTVIRGNASEILALAGAETRGKGADSADPVAAAEAAAQRLAESSGAVVAVTGPVDFVTDGRRGIRCANGHPLMPRVTALGCSLTGIVGAFAAIRPPFEATAAALAFFGLAGEEAAKTATGPGSFQVAFLDALHALSPEALDRGARLEAA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: AROB_PROMS
Sequence: MNKRKILVPLGDKSYEVTLEAGILNNISEELLKIGITKKRKILVISNEEISNLYGEKFLNNLKDNKFQAKMFLIKAGESYKNLKTLSEIYDVAFEFGLDRNSIIIALGGGIVGDVSGFAAATWLRGIEYIQIPTTLLSMVDSSVGGKTGVNHPKGKNLIGAFNQPKAVFIDPETLKSLPKREFSAGMAEVIKYGVIRDKELFEYLEIEKNKNELINLKNEYLIKIINSSIKTKSNVVSQDEHENGVRAILNYGHSFGHVIENLCGYGKFLHGEAISIGMNIAGKIAIEKGLWSKEELERQRILLESYDLPTEIPKINKEDVLTILMGDKKVRDGKMRFILPKEIGAVDIYDDVEDSLFLKFFS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_BARHE
Sequence: MDNKTDNKNNLTPQSAPSSAPHKERLTPMMEQYIEIKAVNSDCLLFYRMGDFYELFFNDAIEAAQVLGITLTTRGKHLGEDIPMCGVPVHTADDYLQKLISCGYRVAVCEQTEDPAEAKKRGSKSIVRRDVVRLVTPGTLTEEKLLDPTRANYLMTLARIKTSDGEEFALSWIDISTGIFRVTESRLEKLLADIMRVDPQEIIVADSFFHDKSHKSLFNVLDCIVSPQHASLFDVITAERDICSYFKLSTLEGIADYSRPELSAIAAAIRYIEKTQITHRPPLMRPERQNESATLFIDAATRLSLELVRTTSGQRDGSLLKAIDRTVTGGGSRLLLDRLIAPLTTPSAIDKRLDSIAFFLRNTSLAEDIKLILKGGPDMPRAVSRLALGRGGPRDMASIQRGFEIIRELHQLLSNELLPQEISDVQQIFSHLPTALHLRLEQALADDLPLLKRDGGFIRPHYHKELDEMRTLRDESRRVIAELQAQYAQETDIKTLKIKHNNILGYFIEVTNLQATALTNTPQAKARFIHRQTMANAMRFTTTELAELESRIAHAANHALTLELEIFDTLVHEITEQVDFIRKAAESLAVLDVSVALAHLAEEQGYCRPKIDQSLTFCITAGRHPVVEQALRKQAAEPFVANNCDLSLQENHQYAAIWLLTGPNMGGKSTFLRQNALIAIMAQMGSFVPATSAHIGVVDRLFSRVGASDDLARGRSTFMMEMVETATILNHATQHSLVILDEIGRGTSTFDGLSIAWATVEYLHEVNHCRAILATHFHEMTALTEKLDRLHNVTMKVKNWDGDVIFLHEVTPGAADRSYGVQVAKLAGLPKAVITRATDVLQQLEQGEMAGKGHKLIDDLPLFSLKTTSSLNEDTNKYSMLHEAFKNIHPDELSPKQALEALYHLKQLEKNNPL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DAPB_SYNC1
Sequence: MIKVAVNGAAGRMGGRLITAIKETEGLQLTGALEHAESPMLGQDAGLTAGCGPLDVLISSDLDEVLKATDVLIDFTFPEVSLRNLEACVRHDKSIVIGSTGFTPEQRARVDEMAQNIPVVLAPNMSVGVNACFKLLKEAAQILGDGFDVEIVELHHNKKKDSPSGTAVRMGEIVADALGRDYNKSAVYHREGMCGARTPEEIGMQTVRGGDIVGEHTVYFIGMGERIEITHRAMSRDMFARGAVRAASWLAGKAPGLYDMQDILGLK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_OCEIH
Sequence: MEFRYLPMTNQDKQEMLDAIGIKSTEELFSDIPEHVRFKGEMNLKAPISEYELTKELTELASRNIHTKEYTSFLGAGVYDHYIPSVVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMISELTGLPVANSSMYDGGTALAEAVNLSAAHTKRKKVLVSKAVHPEYRAVIDSYTRGQSIDIVEIDTVNGVTDLAQLDQAIDETIAGVVVQYPNFFGQLEPMKKIEQLLENHQKTMLIVSSNPLALGYLTPPGEFGADIVTGDTQVFGIPAQFGGPHCGYFATSKKLMRKVPGRLVGETVDEEGTRGYVLTLQAREQHIRRDKATSNICSNQALNALASSVAMSSIGKHGLRKLASVNMQKARYARKKLLEAGVELAFDGSFFNEFVIKVPGSVSKINKQLLDKGIIAGYDLAKDDKSLEGYMLIAVTEVRTKQEIDQFVKELGDIHV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: FABZ_STRPN
Sequence: MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFFNGHFPQYPVMPGVVIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_FELSL
Sequence: MPQLDTSTWSITIMSMIMTLFIVFQLKISKYLYPSNPEPKSMTTLKQLNPWEKKWTKIYSPLSLPQQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: TRPA_TRIEI
Sequence: MISVSDCFESLRNNSSQCALIPFITAGDPDLETTAKALEVLDRSGANMIELGVPYSDPLADGPVIQAAATRSLNRGTTLESVLEVVQTVSPKLRSPIILFTYYNPILYRGVENFLKKIYDVGARGLVVPDLPLEEADILLEPAKDIGIELTLLVAPTSPKERIKAIAHQSQGFIYLVSVTGVTGMRAQMQTRVEDLLAQMREVTDKPIGVGFGISQPEQALQVKKWGSDAVIVGSAVVKRLAEGSPDEGLKAIGEFCQNLKAAIN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL9_GLOVI
Sequence: MGTKIVLKKDVDTLGKAGTLVEVAPGYARNYLIPQGLAVKATPGLVKEAEFRQAKRREIEAKHRADALETKKTLEALGFYEVFAPVGEDGNQLFGTVTNQDVAEVVASKAGITIDRREITIEEPIKRTGVYTVKARIFQDVVATLRLQVNAAG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.