PharMolix/UniProtQA huggingface dataset:
Protein: MUG_ECODH
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_STRPF
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGKTIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIR_BACSU
Sequence: MNSIIDLFPAFLLVFIRISAFFVTIPLFGHRNVPAVHRIGFAFFLAVICFSTIDKPPSLEIDEHYMLLAFKEALVGLCLGLIAYMMIAAVQIAGSFIDFQMGFSIANVIDPQTGAQSPLIGQFIYTMALLFMLSVNAHHLLLDGIYYSFQYISVDQAFPNFGDEKFAYFIAKSFNAMFIIAFQMSAPVVASLFLVDLALGIVARTVPQLNVFVVGLPLKIAVSFIMLIVCMSVIFVVVRNVFSLTIETMRNLLALVGVS
What is the function of this protein?
Role in flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliR.
What is the protein family that this protein belongs to?
Belongs to the FliR/MopE/SpaR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: DEF2_BIFLO
Sequence: MAIREIRVVPDPVLRTPCDEIKEITPAVRRLVDDLLETVDDPGRAGLSANQIGVSLRAFSYNIDGKVGYVLNPVLEEKSGEQYGDEGCLSVPGLWYKTRRADYARVRGIDLDGNEVVLEGSGLMGRMLQHECDHLDGHVYLDRLEKEERREALRYMRNRQAK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RF1_PYRAB
Sequence: MTRHDAQLYELKKKIEELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGNTDIRLWAIVPPEPLNVRLYRCDQTFVTEPLEEMLRVKDAYGLITVEKNEATIGLLRGKRIEVLDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGEHANRVFLPLLEKGELKGIIVGGPGPTKEDFVEGDYLHHELKKKIIGVVDISYHGEYGLRELVEKASDILRDHEVIREKKLVNEFLKHVVKDTGLATYGEREVRRALEIGAVDTLLISEGYDKVRVRAKCNHCGWEELKTMSEEEFEVYKKKLTRCPKCGSQNLTIEKWDVAEELIKMAEEAGSDVEIISLDTEEGQQFYRAFGGLGAILRFKI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_MYCTO
Sequence: MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: DCD_SALTY
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: VSR_RDVF
Sequence: MEVDTATFVRLHHELLCAHEGPSIISKFDAIKKVKLGTLANQSGGANNITEAFFDKLRNFERKSEAYLASDLAERELTRDTHKAIVFVTKSVLLGGKSLKDLLPYGVIVCAFIFIPETASVLDNVRVMIGNQKRPLTVALIKYMAKSLNCDLVGDSYDTFYYCNSSAYGKNLISVSENDFSNPQRALLSVGDLCYQAARSIHVAAANYIRIFDRMPPGFQPSKHLFRIIGVLDMETLKTMVTSNIAREPGMFSHDNVKDVLHRTGVFSPNHHFSAVILWRGWASTYAYMFNQEQLNMLSGTSGLAGDFGKYKLTYGSTFDEGVIHVQSQFVTPEAVRKRNIYPDLSALKGGSS
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Suppressor of RNA-mediated gene silencing, Non-structural protein 10, Pns10.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus non-structural protein 10 family.
Protein: UBIG_BARBK
Sequence: MINKTRTTVDQSEIDHFSRIAAEWWNPQGKFRPLHKFNPTRLAYIKEKICLAFDRDPFSLAPFAGLKILDIGCGGGLLCEPMVRLGATVIGADAAQNNIEVAKIHATQSGLSIDYRATTAEKLADKGEKFDIILNMEIVEHVADVDLFISATAKMLKPQGLMFIATLNRTWKSWGLAIVGAEYILRWLPKGTHDYKKFLKPQELKKLLLTNSLKVIDELGITYNPLNDSWNRSKDMDVNYMLLVKRLQ
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MATK_PHAJD
Sequence: MYLNSRITRIFRLKKERFWQQNFLYPLLLQEYLYSLAHYHSFNSLIFYEPVEIIGYDNKSSLVLVKRLITQMYQQKSFISSVNDSNQNGFSLHKNSFSYHFYSQMVSEGFGVILEISFSSRLVSSLEEKRIPKSQNLRSIHSIFPFLEDKLSHLNYVSDLLIPYPIHLGILVQILQCWIKDVSSSHLLRLIFHEYHNLNRDIPSKKSIYVLSKERRRFFWFLHNFYVYGCEYIFLYRRKQSSYLRSISSGVFLERTHFYGKIGYLRVVSCYSFQRILWFLKDIFIHYVRYQGKAILASKGTFFLMNKWKFHFVNFWQSYFHFWFQPYRIHIKQLPNYSFSFLGYFSSVLKNPLVVRNQMLENSFLINTLTNKLDTIAPVIFLIGSLSKAQFCTVLGHPISKPIWTNLSDSDILDRFCRICRNLSRYHSGSSKKHILYRIKYILRFTCARTLARKHKSTVRMFMLRLGSVFLEESFLEDEQSLSLIFLHNIPFLLHRLHRERIGYLDIIRMNDLMDHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IRLR_BURP2
Sequence: MRILIVEDEPKTGMYLRKGLTEAGFIADWVEDGVTGLHQAETEEYDLIILDVMLPGHDGWTVLERLRRAHSTPVLFLTARDDVGDRVKGLELGADDYVVKPFDFVELVARVRSILRRGQARESTVLRIADLELDLTRRKATRQGDVVLLTAKEFALLWLLMRREGEILPRATIASQVWDMNFNSDTNVVDAAIRRLRSKIDDAYEPKLIHTVRGMGYVLEVRSASAPSR
What is the function of this protein?
Member of the two-component regulatory system IrlR/IrlS.  May be involved in invasion of eukaryotic cells and heavy-metal resistance.
What are the official names of this protein?
Transcriptional activator protein IrlR.
Protein: RL14_BOVIN
Sequence: MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINAKWAATRWAKKIEAREKKAKMTDFDRYKVMKARKMRNRLIKIEVKKLQKAALLKASPKKALAAKGAAAVAAAAAAKVPAKKITTEGKKAPAQKAPAQKAAGQKAAPPPKTQKGQKAPSQKAPAPKASGKKA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS2_MELLP
Sequence: MMLPTIVEWSEPDQKILLEPYTYLGINTDKELPAMVTRAFNHWYQVPQPALDIILKIVGPIHVASLLIDDIQDDSDLRKGKPVAHTVYGVAQTINTATYVFFDAYRNISKLTPFLKSPEITDLGSIIDDEIMALHRGQGKDLYWRDSLICPTEEEYLRMIHNKTGAMFRLPIKLLQALSPVESLPDCFPLVNIIGILAQIQNDLLSLSREFTEDKGFCEDFSEGKFSFPIIHAIKADSSNSLLMDILRSRPKDEATKRKALRYMNDQTKSLDHAFKVIRKLEKIAKEEIEKLGGNPELSSIFELIHFSSTPEIDDQ
What is the function of this protein?
Terpene synthase that shows monoterpene synthase activity and produces linalool, using geranyl diphosphate (GPP) as substrate (PubMed:32913319).  Shows also sesquiterpene synthase activity as it is able to convert farnesyl diphosphate (FPP) into (E)-nerolidol (PubMed:32913319).
What are the official names of this protein?
IDS-like terpene synthase 2, ILTPS2.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: CARA_MARSD
Sequence: MKAILALEDGTYFEGTSFTGPGESGGEAIFNTGMTGYQEVLTDPSYTGQMVCMTYPLIGNYGITKEDIESAKVHVAAFIVKECCKHPSNWRSVMSLPEYLKEAGVMGIEGIDTRALTRHLRINGAMRGIISTEELDPEKLVAKAKQLPTMEGQNLADTVTSETCYAWQDGKPVPVDVSSGYKWSDKGPRLVLVDYGVKWNILRLLDEQGFEVLSVPSHYSEEQVRALEPDAIFLSNGPGDPAVLDQAVKNAKSYCEDLPVAGICLGHQILGQALGGKAFKLKFGHHGCNHPVMDMESKKIEISSQNHGFCVDISDCSDLKITHKNLNDETLEGFAHKTKPIIAIQFHPEAAPGPHDSCYFFARFRNLVKDATGK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: PRSA_LIGS1
Sequence: MKKKWLVAISGIVLTFGLAACSKTVATTSGGKITESEYYSSMKKTSSGKQVLQQMILNKVLEKEYGSKVSDKKVNEQYNTYKKQYGSSFDSVLAQNDMTKSSFKQEIRSNLLLKEAVKDNTKITNKQLKAQWKEYEPKVTVAHILVSKKSTAEDIINKLKEDGSYANFKKLAKKYSTDSSTKNDGGKLAAFDNTDTSLDSTFKKAAFGLKQGSFTTEPVKTEYGYHVIYSIKNPGKGKMSDHTSELKSQIIDSKMSDSTTLQTVVSKVLKKGNVSIKDKDLQNILSSYLGSSSSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: EGG1_CAEEL
Sequence: MSQQPGSARRVNFPEEPMTLGEKFSHRMDQLKEIIADGGCSRAAKCVSITVCLVLLVLIFGGAIVYLVMSLTSSAQKMSADSMDISPQAIRHPKFWPPTDKIRFDDLNGIPMTSLFPQNVSTCSGFGFACTGAVHMVIPSSKRCDGRRDCEDGSDEENCKECQSVFSCKLRPEEESKKKGRSTVQPTLICLTAQHLCDNVENCPDGSDEAVCKSSCSKDQFKCPGSNACLPLSAKCDGINDCADASDEKNCSKCQNNAHKCGKQCIKASHVCDGVAQCADGSDEQQCDCQRCSGTDKALCDDGTCIMRTQVCDGKKDCTDGMDEEDCPGSCTIESFSPKLKMVTCSDGKQYTEAEACSGSFESCDHDCPNSKCHPKLAFTCPASKEARKMCISRRKVCDGTPDCDDGADEINCTPIKECGIAKNTQFKCDHKCLDSSRRCDGVWDCEDKSDEKGCDKCPSGTIKCAADKKCLPAFTRCNGVADCSDGSDELKCSCQECLGVHSNTYMCNESNRCLKRDEVCSPYSMCPNATYTDKAFCAALFLKKSGTSPF
What is the function of this protein?
Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (PubMed:16360684, PubMed:20971008).  Redundantly with egg-2, seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte (PubMed:16360684).  Conversely, shown to be dispensable for fertilization but required together with egg-2 for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (PubMed:20971008).  Appears to recruit or maintain together to the unfertilized oocyte cortex several proteins including chs-1, kinase mbk-2 and pseudophosphatases egg-3, and possibly egg-4 and egg-5 (PubMed:20971008).
What are the official names of this protein?
LDL receptor repeat-containing protein egg-1, Egg sterile protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Localizes to the cell membrane of developing oocytes (PubMed:16360684, PubMed:20971008). Plasma membrane localization requires extracellular matrix protein cbd-1 (PubMed:20971008). After fertilization, localizes to endosomes in zygotes (PubMed:20971008).
Protein: GLON_GLAL2
Sequence: MDQNPILIQRHHHRQNFAQKAPPAPLFLIHDGGGTVFSYFLLESLGRTVYGISNPNFETESTWENGIASMAEYYVNLIKATYPSGHILLGGWSLGGLIAIQAAHILSNDPELKVVGIVMIDSTFPVEGQFNKARRLAFMAETSTSPDMKEKTRKCMDEARIQSREWKAPSWRSSATETLDNHSQTINVQIHDHVTPTCPPTVLIRALDDGSNNSRDLNETSPTETSNDSETQALGFDRYQNFNLRYVVNTPGDHFSIFNKENVKELSKKVKEACDKLVMKS
What is the function of this protein?
Probable thioesterase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non-competitive inhibition of beta-1,3-glucan synthase (PubMed:27705900).  The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4 (PubMed:27494047).  The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain (PubMed:27494047).  The 10R,12S-dimethylmyristic acid is then transferred to the first thiolation domain of the nonribosomal peptide synthetase gloA/GLNRPS4 by the acyl-AMP ligase gloD/GLligase, followed by its acylation to L-ornithine to trigger elongation of the cyclic hexapeptide (PubMed:27494047).  L-ornithine, 4R-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2), 3S-hydroxyl-L-homotyrosine (generated by gloG/GLHtyB, gloH/GLHtyA, gloI/GLHtyC, gloJ/GLHtyD and hydroxylated at C-3 by the dioxygenase gloM/GLOXY1), 3R-hydroxyl-L-glutamine (generated from L-glutamine probably by the dioxygenase gloE/GLOXY3) and 3S-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2 to yield pneumocandin B0), or 3S-hydroxyl-4S-methyl-L-proline (generated from L-leucine by the dioxygenase gloC/GLOXY4 to yield pneumocandin A0) are sequentially added to the growing chain (PubMed:25270390, PubMed:25879325, PubMed:25527531).  The last C domain of gloA/GLNRPS4 is proposed to be responsible for cyclization by condensation to form the peptide bond between L-ornithine and 3S-hydroxyl-4S-methyl-L-proline (for pneumocandin A0) or 3S-hydroxyl-L-proline (for pneumocandin B0).  Finally, the subsequent C-4 hydroxylation of 3S-hydroxyl-L-homotyrosine and L-ornithine dihydroxylation at C-4 and C-5 are performed by the cytochrome P450 monooxygenases gloP/GLP450-1 and gloO/GLP450-2, respectively (PubMed:25879325).
What are the official names of this protein?
Probable thioesterase gloN, Pneumocandin biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the AMT4 thioesterase family.
Protein: RSMG_BACC2
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFKIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVRESYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGELKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCA_PECAS
Sequence: MSISLSESAAQRVSAFIANRGKGLGLRLGVRTSGCSGMAYVLEFVDDLNDGDTVFEDKGVKVIVDGKSLVYLDGTELDFVKEGLNEGFKFNNPNISGECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NDKB_MERGA
Sequence: MEQTFVAIKPDGVQRGLCGEVMKFIQPMKHYLDLKDMPFYAGLCKYMSSGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTVENAKMEVGLWFKPEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: Y3814_HALH5
Sequence: MPIVTVKFLEGRSDEQKRALVERVTEAVAETIQANPEKIHVVLEEMRKDHYGVAGKRISDQ
What are the official names of this protein?
Probable tautomerase BH3814.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: GCP4_HUMAN
Sequence: MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIEQYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSISHVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCHGVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQDLRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDFYLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEYHGKEHKADATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKYLLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQFSQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNLGPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFGM
What is the function of this protein?
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
What are the official names of this protein?
Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
Protein: BGAL_RHIML
Sequence: MRSVTSFNDSWVFSEASTRDAERSGRVSRSACRTNAVELPFNYFDERCYQRAFTYQRVLAWRPDFSQGSRSSSTRQWPMRSCISTAKRSSRIRDGYTPFEARLTDRLLEGDNLITVKIDGSENPEIPPFGAGIDYLTYAGIYRDVWLKVTDPVSIANIKIETRDVLSDHKAVSLRCDLSNPQGLSFSGTISALLKNAAGEVLAEVAGETTGQSLAFEMDGLRGLSLWDIDDPVLYVIEVELRTGQGFRLLRRAFRLPHGEFTTEGFRLNGRPLKIRGLNRHQSFPYVGLRMGRTAKGSAHADIMNAHRLHCNLVRTSHYPQSKWFLDHCDRIGLLVFARNPRLAAYRWGGMETGGNPERPPHRSSATGTTRLSYIWGVRINESQDSHDFYAETNRLARELDPTRQTGGVRYITDSEFLEDVYTMNDFILGNEELPGANRPGTALRPQQECTGLPRKVPYLITEFGGHMYPTKIYDQEQRQAEHVRRHLEVLNAAYARNPGISGAIGWCMFDYNTTRISAPATGSAITASWTCSASPKFAAYVYASQCDPSEEIVMKPVTFWARGDDDIGGVLPLIVLTNCDEIELKYGSLTKRVGPDRENFPHLPHPPVVIDHRHFTKDELGVWGMKWESAEFTGFIAGKPVADLRMAADPVPTTLQVEADSKTLRREGRDTVRLILRALDQAGNVLPFLNDAVDIEIHGPARLVGPARIVLQGGSGFLAGVHGRRRHASSRSRRRGSAAAKLDLVALADGAASA
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: DHA_STAHJ
Sequence: MKIGIPKEIKNNENRVGLSPSGVHALVEQGHTVLVEKDAGLGSFFEDKDYKDAGADIVSEQSSVWDVEMVIKVKEPLEEEYKYFKEGLILFTYLHLANEEKLTQALVDNKVVGIAYETVQLPDRSLPLLTPMSEVAGRMSAQVGSQFLQKFNGGMGILLGGVPGVPKGKVSIIGGGQAGTNAAKIALGLGANVTILDVNPKRLAELDDLFDGRVNTIMSNPLNIENAVKESDLVIGAVLIPGAKAPSLVTEDMIKQMKDGSVIVDIAIDQGGIFETTDKITTHDDPTYVKHGVVHYAVANMPGAVPRTSTIALNNATLPYAQLLASKGYREAFKANHALSLGLNTYKGHVTHKGVAEAFGLEYTSVEDALKED
What is the function of this protein?
Catalyzes the reversible reductive amination of pyruvate to L-alanine.  May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer (By similarity).
What are the official names of this protein?
Alanine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: FZY1_CAEEL
Sequence: MNNKGRTPGSAGRTVRSSAQQNGLTMRKRDMTPTRNTNLLPNATFVGDRFLGVRLDQDELDHANHLMTSKLYSNKENLNNSMSEPNSPEKKSVEGEALKQMMRHKSTGALTDADDGDRILCYKKNLAPPPAIGYINQAKVLYSTNSVINPASSVKKSTRHVKETATKVLDGPGLTKDLYSRHLDWGCHNWVAVALGHELYLWNTETCVIKNLFEDNAPTNEGLITSVRWSQEGRYISLGYASGAVKIYDPNRPKTTEYVRELRTLRVGGASRCASIAWRKQGVMTCGYKSGDIVNHDVRISQHVVSSWGGDNGHCRDVTALEWSADENMCVSGSSDRTAKIWDGRHVRGSTVIQDPEPMFTIDEHTGQVRTAQFCSFRDGILATGGGINDGTVKLWDVKRQFQKVRELNVCETGGVGGIVFNRPYSEMLTASDDGFLRIYRFNANYKLSHEIQASNEPIMDLVGSPFDEVLIGDMEETLKVFQLFNVDKSTNILDRTAPKNVGLNVR
What is the function of this protein?
Plays a role in metaphase-anaphase transition during meiosis I (PubMed:12498686).  Required for embryonic anterior-posterior axis formation (PubMed:11832245).
What are the official names of this protein?
WD repeat-containing protein fzy-1, CDC20 protein family homolog 1, Fizzy protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
What are the subcellular locations of this protein?
Chromosome. Cytoplasm. Note=At prometaphase, localizes around condensed chromosomes. At metaphase, localizes along chromosomes, dissociates from the sister chromatid after separation and localizes to the cytoplasm at anaphase and interphase.
Protein: GATA_STAAR
Sequence: MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DNJ5B_MOUSE
Sequence: MACNAPNQRQRTLSTSGESLYEILGLHKGASCEEIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTGCYFCCCLCCCCNCCCGHCRPKSSTPEEEFYVSPEDLEEQIRTDMEKDMDFPVVLQPTNTNEKTQLIREGSRSYCTDS
What are the official names of this protein?
DnaJ homolog subfamily C member 5B, Cysteine-string protein isoform beta, CSP-beta.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: PGK_BORT9
Sequence: MSIKTIKDCDFAGKRALVRCDFNVPLKEGNITDDTRIRAALPTIEYLKSQGARVILMSHLGRPKGEKNLKYSLMPVAKRLSELLGQDVKMLPDCIGDEVATTVSCMKNGDIVLLENLRFYKEEEENCDAFVRKLSQNGDIFVNDAFGTAHRAHASTAGLAAYLPAVGGFLMEKEDEFLGKILRNPESPFVAIIGGSKVSSKIAVLESLLPKSNVMVIGGGMAYTFLKVEGYSIGQSLLENEYIDVASSFLKKAKELDVKVILPLDHVVASEFREDSIPEYVDSVDIPNDKVGMDIGEKTLRKIEEVLVSAKTVIWNGPLGVFEFNSFSKGTAKVAEYVASCSGITVVGGGDSVAAVNKFNLSEKITHVSTGGGASLEYLEGKVLPGIKVLEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.