PharMolix/UniProtQA huggingface dataset:
Protein: CIPKK_ARATH
Sequence: MDKNGIVLMRKYELGRLLGQGTFAKVYHARNIKTGESVAIKVIDKQKVAKVGLIDQIKREISVMRLVRHPHVVFLHEVMASKTKIYFAMEYVKGGELFDKVSKGKLKENIARKYFQQLIGAIDYCHSRGVYHRDLKPENLLLDENGDLKISDFGLSALRESKQQDGLLHTTCGTPAYVAPEVIGKKGYDGAKADVWSCGVVLYVLLAGFLPFHEQNLVEMYRKITKGEFKCPNWFPPEVKKLLSRILDPNPNSRIKIEKIMENSWFQKGFKKIETPKSPESHQIDSLISDVHAAFSVKPMSYNAFDLISSLSQGFDLSGLFEKEERSESKFTTKKDAKEIVSKFEEIATSSERFNLTKSDVGVKMEDKREGRKGHLAIDVEIFEVTNSFHMVEFKKSGGDTMEYKQFCDRELRPSLKDIVWKWQGNNNNSNNEKIEVIH
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).  Required for the abscisic acid-mediated (ABA) signaling pathway involved in seed germination and growth elongation inhibition.
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 20, SNF1-related kinase 3.6, SOS2-like protein kinase PKS18.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: MURI_LISMO
Sequence: MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFLVDRGIKMLVIACNTATAAALYDIREKLDIPVIGVIQPGSRAALKATRNNKIGVLGTLGTVESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIAKKVVAESLLPLKSTKIDTVILGCTHYPLLKPIIENFMGDGVAVINSGEETASEVSALLDYHNLLDATDEEIEHRFFTTGSTQIFKDIAKDWLNMPDMTVEHIKLGK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TRUA_PYRAE
Sequence: MPYLYRIAYDGTMFYGFTGHPNSLEPRLRLIFGEILGRGSRTDPGVSAVGNVVMTGRKMALGYVNSKMPKGAWAWGIAEVPEGFNPRRAKLRRYLYVAPHWGEDVDVMREAAKLLTGTHDYSSFIQLRGEKHTPTVTTVYDIDVTLRGDLIFIYFAGRGFRNKMIRKMAWALLAAGRGVLSVDDLADLLKKPRPGAVPSAPAEGLVLLDIVYDVKFEVDFSALRKAYVYFLSKSRHLSAHAAALRAAGEALAMWES
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CAF20_YEAS7
Sequence: MIKYTIDELFQLKPSVTLEVNFDAVEFRAIIEKVKQLQHLKEEEFNSHHVGHFGRRRSSHHHGRPKIKHNKPKVTTDSDGWCTFEAKKKGSGEDDEEETETTPTSTVPVATIAQETLKVKPNNKNISSNRPADTRDIVADKPILGFNAFAALESEDEDDEA
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1/TIF4631 and EAP1 for binding to eIF4E/TIF45 and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.  Binding affinity for eIF4E/TIF45 is 10-fold less than that of eIF4G1/TIF4631.  Required for induction of pseudohyphal growth in response to nitrogen limitation, probably by regulating STE12 translation (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20, 20 kDa cap-associated protein, CCR4-associated factor 2, p20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIE_HAECO
Sequence: MAASNFPHNKKRTLYVGGFGEEVTEKVLMAAFITFGDIVAISIPMDYETGKHRGFGFVEFELAEDAAAAIDNMNESELFGRTIRCNFARPPKATERSSRPVWADDEWLKRYGKGSGIADAKESNGSASTAKGLPRVYLGVKIGIRYIGRIVIELRSDVVPRTAENFRCLCTGEKGFGYEGSSFHRIIPKFMLQGGDFTKGDGTGGKSIYGPKFEDENFKLKHLMPGTVSMANCGPNTNGSQFFICAEKTDWLDGKHVVFGHVVEGMNVVRQVEQQGTPSGKPQMVVKIVECGELDPVPQTEPQENEENSDPQTPMDVEPQKETA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Combines RNA-binding and PPIase activities.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophiline 33, HcCYP, Cyclophiline E, Rotamase E.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: AAEX_YERPG
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MBCT_MYCTO
Sequence: MSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLADSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDIYGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALYQELRAT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Degrades NAD(+) by phosphorolysis.  Neutralized by its cognate antitoxin MbcA.
What are the official names of this protein?
NAD(+) phosphorylase MbcT, Mycobacterial cidal toxin MbcT.
What is the protein family that this protein belongs to?
Belongs to the MbcT/ParT/Res family.
Protein: UREG_FRACC
Sequence: MHLGHEEFQRTDGRASTGPADAGPAGAGRAPRIGVGGPVGSGKTALVAALCRALSSSLRIGVVTNDIYTTEDADFLRRAGVLDPERIRAVETGCCPHTAIRDDITANLDMVEDLEADTGPLDLVLVESGGDNLTATFSYGLIDRQIFVVDVAGGDKVPRKGGPGVTGSDLLVINKTDLAPLVGADLDVMARDATAARGARPVVFTSLTADPTAADVTAWVRAQLAELSPRGGSYDASDASNASQPLNRM
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4MQ_SINFN
Sequence: MLQTTSLSAMRIFEAAARLGSFRAAAEELNLSPSAVSHAIMRLERDLGVALFERTTRSVSLTVAGQTLLNHASNAFEELRRGVEQISSNKAQLLRLHCAPSFAAQVLSPRLPQFLKENPGIEVRVAASTNYARFVDGLFDADIVYGEPLNREDLIVIPLSEEIVLPLCAPDLAHQIKSPRDLFHQPLIRSDLKRIQWIDWFEANDLGPPPSPSMSFDRSFLAVDAAVNGLGIALESDVLARRELESGKLVRPLHRICRDNRYIGHYLAYPKSGSQRRLARAFADWLTRECQPASTGSE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator y4mQ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GAG_MLVCB
Sequence: MGQTVTTPLSLTLDHWKDVERTAHNQSVDVKKRRWVTFCSVEWPTFNVGWPQDGTFNRDIITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWVKPFVHPKPPLPPSAPSLLPEPPLSTSPRSSLYPALTPSLGAKPKPQVLPDSGGPLIDLLTEDPPPYRDPGPPPSDRDRDDGEAAPAGEAPDPSPMASRLRGRRELPVADSTTSQAFPLRSGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLLTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGEDGRPTQLPNEINDAFPLERPDWDYNTQRGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIKRETEEKEERRRAEDEQKEKERDRRRHREMSKLLATVVSGQKQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLALDD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10-Gag]: Virion. SUBCELLULAR LOCATION: [RNA-binding phosphoprotein p12]: Host cytoplasm. Note=Localizes to the host cytoplasm early in infection and binds to the mitotic chromosomes later on.
Protein: METAA_CLOTE
Sequence: MPIVIPKDLPATETLENENIFVITEHRAIHQDIRPLKIAIVNLMPKKIETETQLLRLLGNIPIQVSIDLIHPKTHHSKNISEKHLLSFYKTIDDIKNEKFDGMIITGAPVEQIAFEDVDYFQELKTIMDFSVTNVFSTLHICWGAQAALYYHYNINKNILPKKVFGVFSHHININKGTVKLLRGFDDKFYVPHSRHTEVKKEDIEKVPELEIFAESNEVGPYIIASKNGRQIFITGHPEYDANTLKSEYYRDINLGKHIEIPKNYFKNNNPREELIANWRGHANLLFSNWLNYYVYQETPYSYISI
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_ATRBE
Sequence: MNSIQFPLLDRTAQNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISRELYEDRIRSQRVNRCFTTNHKFHVRRSIHTGNYDQRVLYQPPSTSEIPTEIFFKYKNSVSSPELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MUTH_VIBPA
Sequence: MKPEPQSEAELMERAHDIAGLSFAELADEAGMTVPENLKRDKGWVGQLLEWHLGAPAGSKPQQDFSKLGIELKSIPIGYNGRPLETTFVCVAPLTGVQGLTWETSHVRNKLSRVLWVPVEGEREIPLAERRVGTPLIWSPDKEEEQILRNDWEELMEMIVFGKFDQISARHGEALHLRPKAANAKALTEAYSSNGKPMKTLPRGFYLRTQFTEQILLKHYINVQSE
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUB2_ARTOC
Sequence: MQLLNLGLLLLLPFVAGEIAPQPEPLRAGPSDIVPGQYIVTLKEGLASAQIREHKKWVSSVHQANLDSFAAGASGVETVGIMKNFHIHNLNMYSGGFDDKTAEDLRRSPDVKSVHPDQHVYLAKTVTQPQARWGLGYMSSKGKPVPLHSTLVDYLYDDKAGEGVWAYVLDTGINVDHIEFEGRGILGHNAIPNKPHTDEFGHGTYVAGIIAGKTYGVAKKANVVSAKAFDTGSSTYNYILETYDWIVKNITDSNRKNKAVINLSISGAKYQPFDDAVENAFKAGITTVVAAGNDGKDAKNNTPASSPNAITVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKGGNNATSTQSGTSAASPHVAGLVAYLMSLENLPSPSAVTARVLNLTIPNLVKDAKDSPNRVVYNGIQERKFTLPKNTK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYOE_COXB2
Sequence: MRTRTEIVSTTQTSATWRDYFQLCKPRVVLLMLLTAIVGMCLASPGIVSWRVFLFGNLGIALAASSAAAINHLLEHHLDKLMRRTYRRPIVQGKINRKNAAIFAAILCILSMIILIAFVNLLTALLTFITLIGYAGFYTLYLKHATPQNIVIGGLAGAAPPLLGWVAVTGHIDPPALILLLIIFLWTPPHFWALAIHRIDDYAKANIPMLPNTHGIIYTKINILLYTLLLTAISFLPFVIMTSGWIYFSSVCLLNLGFLYWAIRLLTSQRKEIPMRTFQYSIWYLMLLFTALLVDHYVYLALKLY
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPC_SYNFM
Sequence: MSDFLSTILEEKKREVEQRKRTISEEFLEERSASAMERRSLCRALATPGRRGINIIAEVKRGSPSRGVMNPGLDAAQFARRYESCGAAAVSVLTDAGFFHGKAGDLRSARAAVKIPVLRKDFIVSRYQIFESAVMGADAVLLIVRAISPELLGECLRLCRRIGLDALVEVHSAEELDAASEAGAVLIGMNNRDLSTFTTDIRTSIQLVRRMRPGQVAVSESGIRCREQIDRLLDAGIWNFLIGESLVTAPEPEAVLAHLFGAYAA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: VATB_CANAL
Sequence: MSLSDKELFELNKKAVTEGFKIKPRINYNTVGGVNGPLVILDNVKFPRYNEIVNLTLPDGSVRQGQVLEVRGTKAIVQVFEGTSGIDVKKTRVEFTGENLKIPVSEDMLGRIFDGSGRPIDKGPKIFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETSRFFKQDFEENGSLERTTLFLNLANDPTIERIITPRLALTTAEFLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSTEDKLSLEFLEKFEKNFISQGAYENRSIFESLDLAWSLLRIYPKELLNRISPKILEELYGRDREQDDDEDEDEEDPDKSGDKLIDA
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  Plays an important role in resistance to several stresses, as well as in autophagy and virulence (PubMed:25038082).
What are the official names of this protein?
V-type proton ATPase subunit B, V-ATPase subunit B, Vacuolar proton pump subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRG_ANAMF
Sequence: MSIGDVCSARFIFVTGGVVSSLGKGLAAASIGALLQARGFRVRLRKLDPYLNVDPGTMSPAQHGEVFVTDDGGETDLDLGNYERFTGVNTTKEDNITAGRIYQQLLAKERRGDYLGHTVQVIPHVTDLIISFILSNDDGADFIICEIGGTVGDIESQPFLESIRQVSYRLSKNFTIFVHLTLVPCVGSAGELKTKPTQHSVKELSSLGIQPDIILYRSAEPLPQYQSAKIANFCNVSADNVIPALDVESMYKLPVMYHAHKLDTQILSHFGMGAPEPDLTKWANVLTMVNNARNVVTIAIIGKYTKFLDAYTSLTEALDHAGMHSGIKIQVKWVDSRLPVRESDLHDVDGVLIPGGFGDDGVDGKVLAIGYARANGIPMLGICMGMQLAAIEFALNVAKLEDANSTEFNQACKNPIVVELPWLQKGEGEYLLGGSMRLGSCTYRLSADSRVASVYGSTVINERCRHRYCINPQYKNVLEEHGLSFTGMSDSHGLVEVLELQSHPWFIGVQFHPEFKSSPFAPHPLFTSFVQNVLQIKQRGFMHKSVSAAAILVPGSSVVS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MXRA8_XENLA
Sequence: MEIRCKVLVCHIILLHSATVYLYSVPASQQNPESVVVSVTNISTHVGDQGFLTCESYRMVWTQDNLMDRQRVVHWDLYNSQGVYRGERLLDMFSAGEQRIYKDYNQRRISVSESAFQDGNFSLVIKDVSMIDQGLYSCNLHHHYCHLDETVRVQLNITKSERKVKIYWDGEKIVIVALVHSTVLLPCENHDHMWTDRHREEDQQVVHWDRQAPGIPHDRADRLIDMYASGERRAYGSLFLRRKMNVSNSAFSQGDFTLFIPYLTRGDEGTYSCHLHHHYCGLHERRIFYLSVSDRPKTEEPSKTNSDSAPAIDSNVVQENKVINVTIQESRLHFFQQLGYILATLLLFILLLTAVILITRKHQKRGYAYNLNKPQGKEVNMQEICLRPPDLIQYKKEELRIDYKNNILKERAEMDRVFAPKNIDLDLELRKEYCK
What is the function of this protein?
Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3.  Mediates heterophilic cell-cell interactions in vitro.
What are the official names of this protein?
Matrix remodeling-associated protein 8.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: THIM_CHLSY
Sequence: MTLNERIAELRERVRQQRPLIHHITNFVVMNDTANVTLHIGGLPVMAHDRAEVAEMVTAAGALVLNVGTLSPDWIEAMLIAGRRANELGIPIVLDPVGAGATSLRTASNRRLLEELQIAVVRGNSGEIGALAGMGGVVKGVETVVEVDDPTAAAKALAQQYRTVVAVTGRQDVVTDGKRVFLVDNGHEWLKTLTGTGCSATTVIAAFAAVEREYPFAAAAALACFGLAAELAAPAARGPASFKVAFYDAIYHLSADQIRAGARVTAVAG
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: DNAA_RUEPO
Sequence: MTQEKWGLLCQKLLKTVGQNNFTTWIEPLEFQALENGVAVFTVPTNFMGNYVSQNFSDLILYELNNAGEAVQRLAFRVAANSPMRPARAARPAAAAAAAAAAVEAPQVSAPRATDTSDVLDGLQAAPLDPRFTFDSFVVGKPNELAHAAARRVSEGGPVTFNPLVLYGGVGLGKTHLMHAIAWELKVKRPELNVLYLSAEQFMYRFVQALRERRMMDFKHLFRSVDVLMVDDVQFIAGKDSTQEEFFHTFNALVDQNKQIIISADRAPGEIKDLEDRVKSRLQCGLVVDLHPTDYELRLGILQTKVQMYRTTYPDLVIADGVLEFLAHRISTNVRVLEGALTRLFAFASLVGREIDMELTQDCLADVLRASERKITVEEIQRKVSDYYNIRLSDIIGPKRLRSYARPRQVAMYLCKQLTSRSLPEIGRRFGGRDHTTVMHGVKRIEELKLTDGQIAEDVEMLRRALEA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR56_ARATH
Sequence: MILCLRLCLRASRSFFSISTTNNNNNLSRFLFRFSTLPHCAASSSSSSSNLESYYANLILSSHGDSNKPNRKWSSHQFRLLLTDPNLLIRVLNMIRVKPEIAFRFFNWIQRQSDVKQSRQAFAAMLEILAENDLMSEAYLVAERSIDLGMHEIDDLLIDGSFDKLIALKLLDLLLWVYTKKSMAEKFLLSFEKMIRKGFLPSVRNCNIVLKVLRDSRMMNKASAVYETMIEHGIMPTVITFNTMLDSCFKAGDLERVDKIWLEMKRRNIEFSEVTYNILINGFSKNGKMEEARRFHGDMRRSGFAVTPYSFNPLIEGYCKQGLFDDAWGVTDEMLNAGIYPTTSTYNIYICALCDFGRIDDARELLSSMAAPDVVSYNTLMHGYIKMGKFVEASLLFDDLRAGDIHPSIVTYNTLIDGLCESGNLEGAQRLKEEMTTQLIFPDVITYTTLVKGFVKNGNLSMATEVYDEMLRKGIKPDGYAYTTRAVGELRLGDSDKAFRLHEEMVATDHHAPDLTIYNVRIDGLCKVGNLVKAIEFQRKIFRVGLVPDHVTYTTVIRGYLENGQFKMARNLYDEMLRKRLYPSVITYFVLIYGHAKAGRLEQAFQYSTEMKKRGVRPNVMTHNALLYGMCKAGNIDEAYRYLCKMEEEGIPPNKYSYTMLISKNCDFEKWEEVVKLYKEMLDKEIEPDGYTHRALFKHLEKDHESREVEFLERLLLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g22960, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LIPA_PARD8
Sequence: MAQHLRKPDWLKIRLGGNEQFTKTKSIVESHCLHTICTSGKCPNMGECWSRGTATFMIGGEICTRSCRFCNTLTGKPLPLDPKEPANVAESIRLMNLKHAVITSVDRDDLPDLGASHWVNTIRTIKEVNPQTTVEVLIPDFQGRLDLVDQVVDAAPEIISHNMETVRRISPQVRSAAKYDVSLSVLRRIAERGVVAKTGIMVGLGETEDEVLELMDDVLQAGVSVLTIGQYLQPSRKNIPVSEYVTPERFEYYRQQAVNKGFKKVESAPLVRSSYHAEKHI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_HELPS
Sequence: MSLIVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFKWVGLEHDGEILYQSKRFGIYKEYIQKLLDEDKAYYCYMSKDELDALREEQKARKETPRYDNRYRDFKGTPPKGIEPVVRIKVPQNEIIGFNDGVKGEVKVNTNELDDFIIARSDGTPTYNFVVTIDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHVPMILNEEGQKLSKRHGATNVMDYQEMGYLKEALVNFLARLGWSCHDKEVFSMQELLKWFDPKDLNSSPSCFSWHKLNWLNAHYLKNQSAQRLLELLKPFNFSDLSHLNPTQLDRLLDALKERSQTLKELALKIDEVLIAPVEYEEKVFKKLNQALVMPLLEKFKLELNKANFNDESVLENAMHKIIEEEKIKAGSFMQPLRLALLGKGGGIGLKEALFILGKTESVKRIEEFLKN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3A_XENTR
Sequence: MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVIKSKKHRTWQKIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKLAEERTEAAKESSQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSKVERLYHDIAQQAFKFCLLYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFALSKKPPKPQLMANYYNKVSTVFWKSGNTLFHASTLHRLYHLSREMRKNLTQEEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIILEKQRRLATLLGLQAPPTRVGLINDMVRFNMLQYVVPEVKELYNWLEMDFHPLKLCTRVTKVLDWVKEQAEKEPELQQYVPQLQSNTILRLLQQVAQLYQTIEFSRLASLVPFVDAFLLERAIVDAARHCDLQVRIDHSSRTLSFGSDLNYSTREDAPFGPFLQNMPSEQIRNQLTAMSCVLSKAVGAIKPAHVLQEKEEQHQIAITAYQKNSRKEHQRILARRQTIEERKERLENLNIQREKEEMEQKEAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIENLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLLKKAYEEQRINDMELWELQEEERISTLLLEREKAVEHKNRMSRMVEDKELFVSKLKASRQSLYEAKLKQFQERLAEEKAARLEERKRERKEERRVNYYRDKEEEEERLREEQLKQEREEQEKVENEKREAEQRDYQERLKKLEEQERKKRQRELEIEERERKREEERRGGDDTFRKDSSRWGEREESGWRRGADPDERKQVPPERDWRRGGPDSKPVINEDASNREEDENAALRKDEEQVSSRAFEEKVSLPDADEEKGGSWRDEDRGPKRGLEEDRGPRRGIDDAGPRRGFEEDRGPRRGIEDDRAPRRGFDDDRGPRRGFDDDRGPRRGFDEDRGPRRGIDDDRGPRRGFDEDRTPRRGFDDDRGPRRGFDDDRGPRRGFDEDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFEDDRGPRRGFDEDRGPRRGFEDDRGPRRGFDEDRTPRRGFDDDRGPRRGLDEDRGSWRGGDDVPRRGADDDRGPRRGADDDRGPRRGEDRDQTPWKPMAASRPGGWREREKAREDSWGPPRDSQAPEEREWSRQGEDSEKDSERDRRPVREESAWRRGGDNSETPRKPSPGDSDRKDDSDKKRPPKTDEANPWRRGEDKDSREEERGTPRRAPAADREKSAWRTEKKEEKDTPRRIKPETDEDGWTTVRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP3B2_HUMAN
Sequence: MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVCASQETFGMKLSV
What is the function of this protein?
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes).  Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.  While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
What are the official names of this protein?
Microtubule-associated proteins 1A/1B light chain 3 beta 2, Microtubule-associated proteins 1A/1B light chain 3B-like.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Endomembrane system; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: RL17_HAMD5
Sequence: MRHRKSGRQLNRNSSHRRAMFRNMASSLVRHEIIKTTVPKAKELRRVVEPLITLAKTDSVANRRLAFARIRDNDIVVKLFNELGPRFVSRAGGYTRILKCGSRAGDNAPVAYIELLDRSVSEPEPTTHTNA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.