PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_STRP7
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDSMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US16_HCMVM
Sequence: MGLRFPTATQRQIVFRRLFDSGNNDDYDEAAVVAVLGWVHRFEVVVRIAGLLLFQISTAVAVLGSFSLVFPTATLKSRPGFPCHVVWAPEVLLLVPVASALFVYFRYERPVLAQRNRHPRCRRPFRQLVLLLAGLLAHIPALGVTCACQEPREVLTSFVLTLVITLLCAEVVFICRDNCTLSDQFALINGVWVVVFLANVLIVFTRPWTWPLRLLLGFYSTVGLIFAGHFSQQVLFVRHVLMPRDVAHTSLQLFITFISLFFLILRIRNCQDLLSDLRLLELPSSDAMTLTPNDLSHASSSTPLSTLSP
What are the official names of this protein?
Protein US16.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Host cytoplasm. Note=Localizes in cytoplasmic assembly compartments but not present in virions.
Protein: PRSW_GEOKA
Sequence: MFSLISAGVAPGVALLSYFYLKDEYEAEPLSFVLRMFLFGVLLVFPIMFIQYVLAAEGIVASPAAEAFLSAALLEEFVKWFVVYFFVYDHDEFDEPYDGIVYSASVSLGFATLENILYLLANGVETAIARALLPVSSHALFSVIMGFYFGKAKFAVKKRRYYLWASFLLPFFLHGVYDWLLLAKERWGYYMGLFMLALWWAALRKVKQAKGYARPQAVPPVKSQA
What is the function of this protein?
Involved in the degradation of specific anti-sigma factors.  Responsible for Site-1 cleavage of the RsiW anti-sigma factor.  This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
Protease PrsW, Protease responsible for activating sigma-W.
What is the protein family that this protein belongs to?
Belongs to the protease PrsW family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRC_ANADF
Sequence: MDANLRKTLDELPAEPGCYLMKDRRGAVVYVGKASSLRSRVRSYFDASRGDDRAFVALLDELLGDVEVIVTRSEKEAVLLENELIKRHRPRFNIRLRDDKDFIVLRLDERHAFPRLEVRRAREPRRAGARYFGPYSSASSIRETLRVVNRHFQLRTCTDHVFEHRKRPCILYQIKRCPAPCVYDVPEAEYRQSVEDAIEFLEGRETELVERLHGRMDEAADALRFEDAARLRDQLQAVERSLEKQRVLMADRADRDVVGLYREGPDLVVQVLAMRAGKLQDSRSYPFHEQEFPDEETLSSFLSLYYEQNAAPEEILVPVEPAEVDALADVLSERRGRRVRLLTPQRGAKADLLEVAARNAEQGFRSWHEKDERREQALAALTRALHLARPPRWMECYDISTFQGALAVGSGVSFRDGEPDKACYRRYKVKGVAGQDDFAMLYEVVSRRLRRALGEGAFPDLLVIDGGKGQLNAALAAAKDLGVPTKPSPGNEGAPFVELVGLAKSRLVDAPALGTTRVIGRRGRGGGASRAASGAAALADAAEAQEHGFVSELARSPERVFLPGRKDPVVLRQNSAELFLLARLRDEAHRFAITFHRKLRRERNFQSVLEEISGIGEGRKRALLRHFGALRRVKEATLDEISQVDGFGPKQARAVFEFFHPPRREGAEGAAVVGPPSAAAAPPIETAAVAEAVSEEDIDAALAAEDEDAEGPAPVE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN830_DANRE
Sequence: MAASRKGKAVKAVKQEDLRRLMQETRRDSGRQKRVESPFARYSGAGQLMCALCDAPVKNALLWQTHVLGKQHKDKLQELKSRTAPAHTPAPAHTPAHTPAAASSSSSTLKRAAEPPPAPGKRAKLQTGAGAGLGLLAGHYDDDDDDEGGAGERKTAPPTDSALPADFFDSGPAPAPPISHSGSVSKAEQQESQEPPENRPESLPEGFFDDPVRDAQVRQVDTPKDQLEREWEEFQKEMRQVNSASDAIVAEDDEEGRLERQMDEIEEQMQCLRRVEELRAKQETARSRRRSQRREEEPMQEEEPLEEEEELMHILTQDWRAKGALA
What is the function of this protein?
May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity.
What are the official names of this protein?
Zinc finger protein 830, Coiled-coil domain-containing protein 16.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus speckle. Note=Excluded from nucleolus.
Protein: ENO_COCLU
Sequence: MAITKIHARSVYDSRGNPTVEVDIVTETGLHRAIVPSGASTGSHEACELRDGDKTKWGGKGVTKAVANVNDIIAPALIKEKLDVKDQSAVDAFLNKLDGTENKTKLGANAILGVSMAIAKAAAAEKGVPLYAHISDLAGTKKPYVFRFLSKNVLNGGSHAGGFLLFQEFMIAPAKTFAEALRIRQGAEVYQKLKALTKKTYGQSAGNYGDEGGVAPDIQTAEEALDLIVDAIEAAGHTGQIKIAMDVASSEFFKDDEKKYDLDFKNPDSDKSKWLTYPQLAEMYKSLAEKYPIVSIEDPFAEDDWEAWSHFYKDGDFQIVGDDLTVTNPEFIKTAIELKSCNALLLKVNQIGTISEAINAAKDAFGAGWGVMVSHRSGETEDVTIADIVVGLRSGQIKTNAPARSERLAKYNQILRIEEELGDKRLFAGNKFHTAINLYL
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDB28_HUMAN
Sequence: MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD
What is the function of this protein?
Lack UDP-glucuronosyltransferase (UGT) activity.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B28, UDPGT 2B28, UGT2B28.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm, perinuclear region.
Protein: YIDD_PROM1
Sequence: MLTKINKAIALVFVSLISFYQKWISPLFGPSCRFIPSCSAYGIEAVNKHGPWRGGWLTLKRLSKCHPFTPCGCDPVPEK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TSAC_SHEPA
Sequence: MLQVLPADAAELVEQGGVIAYPTEAVYGLGCDPDNDEAINQLLQIKQRPWQKGLILVAGDYQQLLPYIDESQLNAQQLAFAQSKWPGPFTFIMPVKPGLSKLLSGAFDSIAVRVTAHAGVKALCAAIHKPIVSTSANLSGQEPALSPLAVKQQFEGIISGLVVGELGSQASPSTIIDARSGTVIREG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP3_HUMAN
Sequence: MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQDGEDG
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
What are the official names of this protein?
Ras guanyl-releasing protein 3, Calcium and DAG-regulated guanine nucleotide exchange factor III, Guanine nucleotide exchange factor for Rap1.
What is the protein family that this protein belongs to?
Belongs to the RASGRP family.
Protein: RLMH_DICNV
Sequence: MDITIIAVGNKMPDWVNEGFSDYATRFNAEINMQLKEIPLQKRGDDKQIAAARSKESAQILAALAGKDYVVTLDIAGKNYRSEQLAARLQFWQENARSLALIIGGPEGLSAEVKNRAQESWSLGALTLPHPLVRIIVAEALYRAWSINHHHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_XANAC
Sequence: MPSRSKSSQRWLKEHFADPYVKKAQAEGMRSRAAYKLEELLQRDRLLKPGMVVVDLGAAPGGWSQQVRKSMGDSGRVVALDILDMPALAGVEFLHGDFREQAVLSQFEAMLGDVPVDLVLSDMAPNKSGMDAVDQPRMMHLAELAMEFADTHLKPGGAFLIKLFQGVGSDDYIRELRRRYEKVTIRKPAASRKRSPEVYALGQGKRVQIK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED7_CANAL
Sequence: MSTNNTTTNNEDLISSLYPPPPPYYKFFTKDNLQKLSTWQENNQTTTVSSEVKLEEENTDPDSNNSEENSIPPGELRFLIPPKQPEGPQYRGYGNIWLFEDKLPNLKDSQWEQLYNTSTSTFTSTSTSTANTNIITNTDTDINGNQEVDAGDSTGDENLTSETKIKELHKLMDSLLLNFLELIGILSIDPIKYDKKIHDINLILININHLLNTYRPHQSRESLIMLLKNQIDYKFLEIDQINKKCLDIKSKIKNLINERITVVSDGTTTNTTTTTKTTGLGDGDSIDEKEQLKQDIINRLLSSI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTT3_ARATH
Sequence: MKLKVYADRMSQPSRAVLIFCKVNEIQFDEILIYLANRQQLSPEFKDINPMGKVPAIVDGKLKLSESHAILIYLSSAYPSVVDHWYPTDLSKRARIHSVLDWHHTNLRPGAAGYVLNSVLGPALGLPLNPKAAAEAEQLLTKSLTTLDTFWLKGNAMFLLGSNQPSIADLSLVCELTQLQVLDDKDRLRLLSPHKNVEQWIENTRKATMPHFDEVHEVLFRAKDRCQKQREMATASKPGPQSKIIQFSTIGEKSDDPNLVQNTTDRRKHRRKWSRAEDAILISAWLNTSKDPIVDNEHKACAFWKRIGAYFNNSASLANLPKREPSHCKQRWSKLNDKVCKFVGCYDQALNQRSSGQSEDDVFQVAYQVYTNNYKSNFTLEHAWRELRHSKKWCSLYPFENSKGGGSSKRTKLNNGDRVYSSSSNPESVPIALDEEEQVMDLPLGVKSSKQKEKKVATIITIEEREADSGSRLENLWVLDEEEQVMDRPLGVKSLEQKENKVAPKPTIEEREAADSRSRLENLWALKEKEEREADSRSRLENLWALKEKDIEEQKKLTRMEVLKSLLGRTTDQLSEKEDILKNKLIDEML
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase T3, AtGSTT3, GST class-theta member 3, Glutathione S-transferase 10C.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCSR_ASPCL
Sequence: MVRNMDLYRRSACDRCRRQKLRCVRPLKHGACEHPNNIEALEPCERCSRAGTPCVSTLPPPRKLSRVERLSGLTSVGQLDNLPLQPLIPKQASSHRPGSGSAKSCIPPTGQNKGINDANAVTGSLSMPLPDHRSGSNVHRQPEARPLKRRSRDIHPFGTGSPPTELLDAPSFSTRRSPIFSQAEPFALNDLDFAMQPHSGGDLPSHGDDLFADVLFSPHQKPPAGPTVGESLFDNTKAQELDTRECCLRRLTSLSSRLFHDFNNTNSVKLPDLLSFSPCRNLTAPNQATDCPQNIIGRVLESSHTFLDILHGLAPDPRPTSSSDSECSYSNYWEDDEFVPISDEMTYNSTSARPEFRDSSDMCASSSNRDSSDLSAASPTIDMPTTLTILTCYTWLLQAYDTIFSQIYSSLLAGTDSTSPSMPPVLPGLQIGGFSLDQHCDLQIEILIQLSARMLDRIEGKLGVTDTKDSNAPVDDQEWSRNGSILDTASASTILDALFKQNHSETRAKPGKGARAGSVRNIMKNIRAELTVHK
What is the function of this protein?
Transcription factor involved in regulation of gene cluster that mediates the biosynthesis of the mycotoxins cytochalasins E and K (PubMed:21983160).
What are the official names of this protein?
Cytochalasin cluster regulator ccsR, Cytochalasin biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_ECO81
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQEASEFMAWLRAQSASETIRDYRSQAEQVRDELTAKALAALEQGGDAQTIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PHLA1_RAT
Sequence: MRRTPAAERLSELGFPPRRGSQEPPFPLGVTRGWGGWPIEKRCEGPRPVPFSERSAEDGREQPAHGSGILWRVRTRLSLCRDPEPPPPPPPLCLLRVSLLCALRAGGRGSRWSEDSARLLLLPPAGASGSLKAERSSSTPYAGRMLESSGCKALKEGVLEKRSDGLLQLWKKKCCILTEEGLLLIPPKQVQHQQQQQQQQQPGQGTAEPSQPSGPAVTSLEPPAKLKELHFSNMKTVDCVERKGKYMYFTVVMAEGKEIDFRCPQDQGWNAEITLQMVQYKNRQAILAVKSTRQKQQHLVQQQPPQTQQIQPQPQQPQIQPQPQPQIQPQPQPQPQPQPQPQQQPQPQQLHSYPHPHPHLYPHPHPHAHSHPHPHPHPHPHQLQHAHQPLHSQPQGHRLLRSTSNSA
What is the function of this protein?
Seems to be involved in regulation of apoptosis.  May be involved in detachment-mediated programmed cell death.  May mediate apoptosis during neuronal development.  May be involved in regulation of anti-apoptotic effects of IGF1.  May be involved in translational regulation.
What are the official names of this protein?
Pleckstrin homology-like domain family A member 1, Proline- and glutamine-rich protein, PQ-rich protein, PQR protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles.
Protein: RL7_GLOVI
Sequence: MASERVEKILEDLKALSLLEAAELVKGIEEVFGVKAEAPAGGGMMVMPGVMPGAPAAAAPAEPVEEQTEFTVMLEEVPADKKIAILKVAREITGLGLKEAKDLVEAAPKAVKEGVNKDDAATIKKKLEEAGAKASIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CLPX_BEII9
Sequence: MTKVGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPREICKVLDDYVIGQPQAKRVLSVAVHNHYKRLNHATKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIISTRGKTTSIGFAASVQAPDDRRTGEIFRKVEPEDLLKFGLIPEFVGRLPVIATLEDLDEEALKKILTEPKNALVKQYQRLFEMENTELTFQDEALNVVAKKAIERKTGARGLRSIMESILLDTMFDLPGLDSVEQVVIGPDVVEGKSRPLYIYAERNEKSGTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PETD_EUCGG
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HSLV_AROAE
Sequence: MEQYHGTTILSVRRGRRVALGGDGQVTLGNVVIKATARKVRPIYQGRILAGFAGGTADAFTLFERFEAKLEKHQGNVLRSAVELAKDWRTDRMLRRLEAMLAVADPDNSLVITGNGDVLEPEQGIVAIGSGGAYAQSAARALLENTALPPEEIVKKSLQIAGDLCIYTNQSHVIEVLEG
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEBPE_SHEEP
Sequence: MSHGTYYECEPRAGQQPLEFSGARAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAVKPAPEARELKGPGTPAFPHYLPADPRPFTYPPHTFGPDRKALGPGIYSSPGSYDPRAVAVKEEPRGPEGSRGASRSGYNPLQYQVAHCGQTAMHLPPGLASPSQPLRVLKAPLAAAAPPCSPLLKAPSPAGPSHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
What is the function of this protein?
Transcriptional activator.  C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.  Required for the promyelocyte-myelocyte transition in myeloid differentiation.
What are the official names of this protein?
CCAAT/enhancer-binding protein epsilon, C/EBP epsilon.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YNCP_ECOLI
Sequence: MNLLVKCAGKIPALALTWTCRP
What are the official names of this protein?
Protein YncP.
Protein: SPEH_ANOFW
Sequence: MDTMGRHVISELWGCDFDKLNDMEFIEKTFVDAALKSGAEIREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGHLDPTIAADYIAEALGAQTRETIELPRGMGPIEIKQAKAL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: TRI77_HUMAN
Sequence: MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPCQLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYRKKLLIQMKSIWKKKQKNQRNLNRETNIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAMPQPVNPQLSAWTITGVSERLNFFRVYITLDRKICSNHKLLFEDLRHLQCSLDDTDMSCNPTSTQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAWTKRNDMRLDSEGIFLLLCLKVDDHFSLFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK
What are the official names of this protein?
Tripartite motif-containing protein 77.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: TRPD_CHLFF
Sequence: MLQTYLQSIMNQSHLTYDEAESVTNLMLNGSDPHQIAAFLAVLKYRGETPTEIAGMVSALQKQATSVDLPFPALDIVGTGGDLANTVNISTGSAILSAACGIPIAKHGNRSVSSQSGSADVLEALGIEIEMTPEELLSCIQEVGIGFMFAPIYHPSLKKLAPIRKGMKIPSTFNILGPLLNPANTEYSLIGVSNEPILELMSEVCLQFQNTQRTFLFHGSGLDELTTLGKVVGYDIQQGKKTRIEIDPTSFGFASCKIEELKGGDSKMNAFILKKAFSGQQGAIADALIFNAGAAVWIFGNATTLEEGIQIARQTLMEGEALRVLEKWVAFSQQLKLKRGSCN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL5_BURM1
Sequence: MARLQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAVADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRLVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: VL1_HPV55
Sequence: MWRPSENQVYVPPPAPVSKVITTDAYVKRTNIVYHASSSRLLAVGNPYFAIRPANKTLVPKVSGFQYRVFKVVLPDPNKFALPDTSIYDPTTQRLVWACIGLEVGRGQPLGVGISGHPLLNKLDDVENSASYAASPGQDNRVNVAMDYKQTQLCLVGCAPPLGEHWGKGKPCNNGSVNSGDCPPLELITSVIEDGDMVDTGFGAMNFAELQPNKSDVPLDICTATCKYPDYLQMAADPYGDRLFFYLRKEQMFARHFFNRAGTVGEDIPQDLVFKGATKSTVPNAIYFNTPSGSLVSSETQLFNKPFWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMTICAATTQSPSTTYNSTEYKQYMRHVEEFDLQFMFQLCSITLTAEVMAYLHTMNPGILEQWNFGLSPPPNGTLEDKYRYVQSQAITCQKPPPEKAKQDPYAKLSFWEVDLREKFSSELDQYPLGRKFLLQTGVQARSSVRVGRKRPASAATSSSSKPKRSRKK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PSAE2_ARATH
Sequence: MAMTSAATGFILTANVPAAIGGGSSKSTTIVSFLPMRSFGSRLVVRAAEDTPPATASSDSSSTTAAAAPAKVPAAKAKPPPIGPKRGSKVKILRKESYWYKNVGSVVAVDQDPKTRYPVVVRFAKVNYANISTNNYALDEVEEVK
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV B, chloroplastic, PSI-E B.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.