PharMolix/UniProtQA huggingface dataset:
Protein: DSK_DROPS
Sequence: MGHRGMGCAHFATMAMPLWALTFYLLVVLPVPSQTASVEVGKEERRLQDLDPKMGSEAGNTDGLSLARFGSRRHQRSTGFGHRVPIISRPVIPIELDLLMDNEDDRTMSKRFDDYGHMRFGKRGGDDQFDDYGHMRFGR
What is the function of this protein?
Drosulfakinin-0 (DSK 0) plays diverse biological roles including regulating gut muscle contraction in adults but not in larvae.
What are the official names of this protein?
Drosulfakinins.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_STRA3
Sequence: MAGHEVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDAGLKEVFEDVLPISNFTDTMDLEFVGYELKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDAKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGDSELVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLVARFFDPRRYDLAAVGRYKINKKLNLKTRLLNQTIAENLVDGETGEILVEAGTVMTRDVIDSIAEHIDGDLNKFVYTPNDYAVVTEPVILQKFKVVAPTDPDRVVTIVGNSNPEDKVRALTPADILAEMSYFLNLAEGIGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRSTGAVTNEIVWLTADEEDEFTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFPSSIVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAKHDGRVIFSDAEKVEVRREDGSLDVYHVQKFRRSNSGTAYNQRTLVKVGDLVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEDSLRDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGVVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWETVQEAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDVMHVDDLEKARVKQEAEEKQAEQVSEVVQED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: Y816_MYCUA
Sequence: MARTHDDKWDLASSVGATATIVAAGRAMASRDPRGLIDDPFAEPLVRAVGVDFFIKMMDGEFDLSVLQNVSSAKAQAMVDGMAVRTKYFDDYFGDAIKSGIRQAVILASGLDARAYRLPWPADTVVYELDQPQVIEFKTNVLADLGAEPRATRRAIPIDLRGDWPVALRAAGLDTTAPTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTVATEFVPGIVDFDVDRARQMSGPFRDHGLDIDMSSLVYTGARNHVVDYLRAKGWDAEGVTRSKLFERNGMAVPAPSDDDPLGEIIFISAALTG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_0816.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: ALR1_STAAC
Sequence: MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 1.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: METJ_VIBVU
Sequence: MADWNGEYISPYAEHGKKSEQVKKITVSIPLKVLKVLTDERTRRQINNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPTEAKELMTAMGIEFEAYDD
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCMC3_HUMAN
Sequence: MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR
What is the function of this protein?
Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane.  Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter.  By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways (PubMed:15123600).  Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP (PubMed:24430870, PubMed:28695448).  In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides (PubMed:15123600).
What are the official names of this protein?
Mitochondrial adenyl nucleotide antiporter SLC25A23, Mitochondrial ATP-Mg/Pi carrier protein 2, Short calcium-binding mitochondrial carrier protein 3, SCaMC-3, Solute carrier family 25 member 23.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: SERC_SHESM
Sequence: MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLRELMHIPQNYHVLFMHGGGRGQFSAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFNTPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMNVTFQLADESLDGAFLKEAEAAGLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAAKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKX25_HUMAN
Sequence: MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
What is the function of this protein?
Transcription factor required for the development of the heart and the spleen (PubMed:22560297).  During heart development, acts as a transcriptional activator of NPPA/ANF in cooperation with GATA4 (By similarity).  May cooperate with TBX2 to negatively modulate expression of NPPA/ANF in the atrioventricular canal (By similarity).  Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761).  Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression (PubMed:22560297).  Positively regulates transcription of genes such as COL3A1 and MMP2, resulting in increased pulmonary endothelial fibrosis in response to hypoxia (PubMed:29899023).
What are the official names of this protein?
Homeobox protein Nkx-2.5, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATB2_MOUSE
Sequence: MALRAMRGIVNGAAPELPVPTGGPMAGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:17898041).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (PubMed:17898041).
What are the official names of this protein?
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Apical cell membrane. Melanosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: YG65_SCHPO
Sequence: MAKKKSKASNSARGYATTSIPSRSASSPANKNQVKGEKNNKTQKVEPKNAFKVENQSNDIGVDTVDAFDHLLLDKTLPTIDAETEVIKNTSLSNSKSFLHSWQTDIRLRKNDNVLGLTEDEIQQILKTFRDSWKSSLKESYAFSNRSSFSLRKRYLWTTFLSLKGMGFEESEIFGAFSSIPIVSIDEYITWMITENLINSEPSNSSFSYEVQPSNYTTFCRMLDEPLPANNPVQSNSRLVPLMKDFSNDIKHTPNKETQPSNQVDDSLKSKDSKPLTMSEVLTQLPEDDIPFDDPFDLTSQYVKVKLKMLRLQIANKKNSEEFSTLNLQLESITSQYLFSSKEAEIVFRKSRIEFMNKLKALQQKLENERIVEEIKKNGIQEDSQSTDDSSKDDDNNSESNDMSPHNDAETRADDDAYLMGDLFNQEEEDIQDTENDLLNANYTLLPLTTDKSGTRPSTTLQYELHKIGSNIKAEFKTMPIGKIGYQSTCFVRCSTGQKTFSDLKTVLPTATLAADYISMIVLFRLMANFTKISLQTFPKSFKEVYGKFSAEKQNTDLAEDAKISEKLDSIIKSKELETPTSATTSKLMAPMDNIGKFSGFERPPETLLNKWRQQLESESAEKFKVFRNQLPATMFRETIIDAVNNSQLLIISGDTGCGKSTQIPAFLLENSTKNGKAVKIYVTEPRRISAISLANRVSQELGGNPPSARSHELVGYSVRLDSKCTPLTPLTYVTTGTFLRLLEVGNEIESVTHLIIDEVHERSIDSDLLLIHVLHLLKQHPHLKIIIMSATLNAEKFQLYFEGSNLITIPGKTYPVHRFYLEDILSQFGNDKSFGNAAGQDVIEEDDYETDQQDASISNKSAEDAIVEMNLIPAWYNEKAINYGLIVYLLKYIFTEGDPKFSKCVLVFLPGISEILRVKSLIEDMPMFRNHRKFCIYMLHSTLSSAQQQSVFNIPPKGCRKIVLSTNIAETGVTIPDVTCVIDTGVHREMRYNSRRHLSRLTDTFVSKANAKQRSGRAGRVQEGICYHLFSKFKHDTQFLSYQTPEILRLNLQEVVLRVKMCQMGDVQDVLGKALDPPSSTNIIRALEKLHQVGALSENEKLTKLGKFLSQLPVDANLGKILVLGCFYKCVDAASSIVAMLTIGSPFRKSVDNEFSANKARLSFAKENTRSDLVLMYYAYCAWREICLSPLGPDEDSFAKEKYLNLEALSMTESLKIQLLSELKDMKLLGASDVDTCKSLKRSICRRFAVIPKEHDINSGNAEILCGVIAASLYPNILRYDYEKRQWSTLSTNKRVRILDVSVNNRSELPNMPSKFVAYTNMMSSTRASEYVNETTMVTLRQLLMMCGLKVENRVSVGQAKLDNFTVYFENVYVSASLSILRRFIETSLNEFFAEPDKRLLNSHLEVIVNIVSRLNYGTKFQKRLKD
What are the official names of this protein?
Uncharacterized helicase C15C4.05.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SHEHH
Sequence: MSQNTDSPVLSLAKDLISRQSVTPLDEGCQQLMADRLADAGFNIESMVFEDTTNMWARRGTQSPVFCFAGHTDVVPVGDLNRWHTPPFEPVVIDDYLHGRGAADMKGSLAAMLVATERFIKKFPDHQGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTVKGVQGHVAYPHLADNPIHKAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGALEVMFNFRYSTEVTAEILIERVLNILDAHGLEYDIDWVFNGLPFLTGDGPLLEATKAAIKKVTGTNTDPQTSGGTSDGRFIAPTGAQVIELGPVNATIHKVNECVKVSDLELLTDCYEAILENLLCK
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ISPF_PSEA7
Sequence: MRIGHGYDVHRFGEGDYITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGADSRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGLIAEDLGVALDQVNVKATTTERLGFTGREEGIAVHAVALLMAR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y088_RICPR
Sequence: MIASIWYAELGCASAIAFIFPLIFCVKLDYKCIGIFIINSLHDQYYKPDIMLERAIIIA
What are the official names of this protein?
Uncharacterized protein RP088.
Protein: ATPB_HELPJ
Sequence: MKAMEGKIIQVLGPVVDVEFESYLPAIFEALDINFEVNGTQKALVLEVAAHLGGNRVRAIAMDMTEGLVRNQAVKARGKMIEVPVGEEVLGRIFNVVGESIDNLEPLKPSLTWPIHRKAPSFEQQSTKTEMFETGIKVIDLLAPYSKGGKVGLFGGAGVGKTVIIMELIHNVAYKHNGYSVFAGVGERTREGNDLYFEMKEGGVLDKVALCYGQMNEPPGARNRIAFTGLTMAEYFRDEKGLDVLMFIDNIFRYAQSGAEMSALLGRIPSAVGYQPTLAGEMGKLQERIASTKNGSITSVQAVYVPADDLTDPAPASVFAHLDATTVLNRKIAEKGIYPAVDPLDSTSRILSPQMIGEKHYEIATGIQQVLQKYKDLQDIIAILGLDELSEEDKKTVERARKIEKFLSQPFFVAEVFTGSPGKYVTLQETLEGFGGILEGKYDHIPENAFYMVGSIQEVLEKAKNMKNS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CMOA_CAMJE
Sequence: MKDELFKQSPKKQFEFDKSVASVFDDMINRSVPFYRENLELCGNLLAKILPTNASVCDLGCSSANFLIFLANLRKDFKLFGVDNSASMLEVAKSKAKAYGLDISFFEANLCEFDFFTCDVFVANYTMQFIRPPKRQELLDQIYKNLNSKGILIMSEKILYEDAFLSKNIIELYADYKEKQGYSKFEIAAKREALENVLIPYSQKENLNMLEKAGFKKIESIFKWANFETFIAFKD
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: VM1A_DEIAC
Sequence: STEFQRYMEIVIVVDHSMVKKYNGDSPKIKAWVYEMINTITEGYRDLYIDIILSGLEIWSEKDLINVEASAGNTLKSFGEWRAKDLIHRISHDNAQLLTATDFDGPTIGLAYVASMCEPKLSVGVIQDHSSVNRLVAITLAHEMAHNLGVRHDEKDCVGVVYLCIMRIPVVEDKRSYFSDCSYIQCREYISKENPPCILNKP
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Snake venom metalloproteinase Ac1, SVMP, Ac1-proteinase.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_SYNPW
Sequence: MAKRSLASLNAGDLSGKRVLVRVDFNVPLNDAGAITDDTRIRAALPTINDLIGKGAKVILSAHFGRPKGQVNDAMRLTPVAARLSELLGKPVAKTDSCIGPDAEAKVGAMADGDVVLLENVRFFAEEEKNEAGFAEKLAGLAEVYVNDAFGAAHRAHASTEGVTKFLKPAVAGFLMEKELQYLQGAVDEPKRPLAAIVGGSKVSSKIGVLEALIDKCDKVLIGGGMIFTFYKARGLSVGKSLVEEDKLELAKELEAKAKAKGVELLLPTDVVLADNFAPDANSQVADVTAIPDGWMGLDIGPDAVKVFQAALADCQTVIWNGPMGVFEFEKFATGTNAIATTLAELSAKGCCTIIGGGDSVAAVEKAGLAEKMSHISTGGGASLELLEGKVLPGVAALNDAA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_THEP1
Sequence: MKLVFRWYGEKHDTVTLEQIRQIPGVEGVVGALFDIPVGEVWPLEEIMKLKETVEKAGLKLEVIESVNVHEDIKLGLPTRDRYIENYKETIRNLAKAGVKVVCYNFMPVFDWMRTDLHKKLPDGSETMEYDHRLIEGVTPDELIKRVKEGSQGFVLPGWEWDRLEKLRETFELYKNVDEEKLFENLVYFLERVIPVCEECDVKLAIHPDDPPWSIFGLPRIITNKENIERMLKAVDSPYNGITFCMGSLGANPENNIPEMIRYFGKMGRIHFAHVRNLKFTGEKSFYETAHPSFCGSHDLFEVMKAFHDIGYEGYIRPDHGRLIWGEKARPGYGLYDRALGATYILGLWEAIDKMKKRYC
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: ENGB_ACIBT
Sequence: MSAPKLALCVEDSGYEIAFAGRSNAGKSSAINALTNQKQLARASKKPGRTQMINFFSLGNPDQRLVDLPGYGYAAVPEDMKRVWQKELENYLIHRKSLQGLVLLMDIRHPLQHFDMMMLEWAYSRHLFVHILLTKADKLNRGPANKVLLEVKQQLKKMKLDFSIQLFSSLNKLGLEELASVMAGRLHFTLEQQPEFDVDAIPEASDEDAEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: EIF3J_LODEL
Sequence: MAWDDEDFDIPSNSKTAVSWEDEEDDDPVLESWDIDPEEEAKKKKAEQEAEAKKKAELKAKEDEAKKKRDAKKKEMEEFDGLDERTRKELLKKAELNADLNNAADLFGGLGVAEDGDEDFDINEHPREKARLAALQAARSKPVLTKDTPLEDHPLFQPTNKQEYERLRKTLGATLTALSEDSSLLYASSLAIDLIRDLTQPLSVENTRKVVSTLNVVVKDKERQERTARLKKAGGTSTGGAGKKKAKPAARPNVGGFKKDEFDDMGAFDDLDDDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j, Eukaryotic translation initiation factor 3 30 kDa subunit homolog, eIF-3 30 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_STRP2
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDTDVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTUB2_MOUSE
Sequence: MSETSFNLISEKCDILSILRDHPENRIYQRKIQELSKRFTSIRKTKGDGNCFYRALGYSYLESLLGKSREILKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDSSVSSLLKVFNDQSSSDRIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMAMECDHVQITALSQALNIALQVEYVDEMDTALNHHVFPEAAIPSVYLLYKTSHYNILYAAEKH
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.  Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Ubiquitin thioesterase OTUB2, Deubiquitinating enzyme OTUB2, OTU domain-containing ubiquitin aldehyde-binding protein 2, Otubain-2, Ubiquitin-specific-processing protease OTUB2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C65 family.
Protein: COX14_MOUSE
Sequence: MPSAKQLADIGYKTFSASMMLLTVYGGYLCSVRAYRYLQLRSARRQAAEEQKTSGVL
What is the function of this protein?
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.  Requires for coordination of the early steps of cytochrome c oxidase assembly with the synthesis of MT-CO1.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX14.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: COF_SALHS
Sequence: MARLAAFDMDGTLLMPDHHLGRETIATLARLRERDITLTFATGRHVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASMHVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRIQLNEALEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDREMLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: RL22_STRP1
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ATPE_ECO55
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DEF1_VIBVY
Sequence: MAVLEILTAPDPRLRVQSKEVTDVAAVQTLIDDLLETLYETDNGVGLAAPQVGREEAIVVIDLSENRDEPLVLVNPKVVSGSNKEMGQEGCLSVPDYYADVERYTSVVVEALDRNGKELRIETSEFLAIVMQHEIDHLSGNLFIDYLSPLKQQMAMKKVKKHNKLRAR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.