PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_TRIEI
Sequence: MTNKLDGKALAKKIKAELQQKVQSLQIKIGRPPGLAVLMVGDNPASGVYVRNKEKACTQVGITSLGKHFPTQTSQAQLGQVIQKLNQDPQVDGILVQLPLPKHLDSTSLLYQIDPSKDVDGLHPMNLGQLLRGEKGLRSCTPAGVMRLLQEYKIELQGKHAVILGRSILVGKPMALMLLEANSTVTIAHSRSKNLEAITKKADILITAVGRPKMISAEMVKPGAVVIDVGINRVIDEAGNSQLVGDVQFNSVAQVAEYITPVPGGIGPMTVAMLLQNTVERWSTLVE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: NRDR_CHLMU
Sequence: MLCPFCNHGELKVIDSRNSPEANAIKRRRECLRCSQRFTTFETVELTIQVLKRDGRYENFQEAKLINGLKAASSHTRIGQEQVQAIASNIKQDLLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFRDVGELMEVLLSATPDGEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AIM14_DEBHA
Sequence: MNELESFSPRHEGHHHAANIKYGYIVLGFSVVHIIGILICKSVFKLRWTTSTKGIDFVKSPLFISIIAWTLILIGLGVFHVQLPENYVTSIKRFGRMSYALLPFDIFLVLRPNSIGLRYLELMDLHKWMSRVIIAGAIIHGVGYFIKWILEGSLFTKSVRLWNFLGIVVFMLNLILIIISLRYFRRRIYQYFYVVHNITVWLFVGLICLHARPGVGKYAIACASLLGLQIFERYAKSHSISDLKVISYEGSNLIVVRIQRDSKIADWPSGSHIRLTYPLTNYRSWIFPTHPYTIASLESDEMLDLIISKSNRFILHPQMPYSWTGPFTSFSKELLQTIDNVDIICGGSGISFALPVFRNLKQKASHVKLIWCVRSNNDLHVLRTLNFNEEIIIHITGNLQDSTSNTIFDEEDYGLLDYDNNENFELESLPSSETPSRTVNDDSLSQDTRPKKESKFIIVQGRPDFGNTFESLVQVNSSNKWIIACGPRSLVNSAQEWASENKVNFVSEIYEM
What is the function of this protein?
Probable cell surface metalloreductase.  May be involved in iron or copper homeostasis (By similarity).
What are the official names of this protein?
Probable metalloreductase AIM14.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GRDA1_PHOPR
Sequence: MNKEVFATKTAIILGDRDGIPGQAIEACIKTTGAHVAFSTTECFVUTSAGAMDLENQKRIKALADEFGAENIIVILGGAEAEASGLACETVTTGDPTFAGPLAGVQLGLSCYHVVEDAIKEAVDPAVYEEQIGMMEMVLDVDAIKAEMQQYREEPVEA
What is the function of this protein?
In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity).
What are the official names of this protein?
Glycine/sarcosine/betaine reductase complex component A1, Selenoprotein PA 1, Thioredoxin reductase complex selenoprotein A 1.
What is the protein family that this protein belongs to?
Belongs to the GrdA family.
Protein: KHPA_LACPL
Sequence: MADIKALITTVVTPLVQYPDDIKVDFKETTRYLEYNLTVNPEDIGRVIGRQGRVASAIRTIVYSVRVSGPKRVRLTIEDGQQKNS
What is the function of this protein?
Necessary for correct cell elongation.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DZAN1_MACFA
Sequence: MLTSESFQRVHWKSQLTVEDQVLDHPPAQSPGFAHISGLKCLTSTEIMRIQRETDFLKCAHCLAPCPSDPFARFCQECGSPVPPIFGCRLPPPEGAQMGLCAECRSLVPMNTPICVVCEAPLALQLQPQASLHLKEKVICRACGTGNPAHLRYCVTCEGALPSSQESICSGDKASPPPTQKGGTISCSRCGRWNLWEASFCGWCGAMLGIPAGCSVCPKCGASNHLSARFCGSCGICVKSLVKLSLDRSLALAAQEPRPFSEPQCAWQSLNIPLPRSDAGTKRDIGTQTVGLFYPSGKLLAKKELEIASQKQRQEKMSDHKPLLTAISPGRGYWRRQLDHISAHLRCYAQNNPEFRALIAEPRMGKLISATVHEDGCEVSIRLNYSQVSNKNLYLNKAVNFSDHLLSSAAEGDGELCGSRSSWVSDYSQSTSDTIEKIKRIRNFKTKTFQEKEEQLLPENRLLLKEVGPTGEGRVSVIEQLLDEGADPNCCDEDNRPVITVAVMNKHHEAIPVLVQRGADIDQQWGPLRNTALHEATLLGFAGRESVATLLGCNASVRKKNAGGQTAYDLALNTGDDLITSLFAAKFGQGLEDQLAQTRSLRLDDC
What are the official names of this protein?
Double zinc ribbon and ankyrin repeat-containing protein 1.
Protein: EIF2D_RAT
Sequence: MFAKAFRVKSNTAIKGSDRRKLRADVTVAFPTLGTDQVSELIPGKEELNVVKLYAHKGDAVTVYTSGGNPILFELEKNLYPTVYTLWSHPDLLPAFITWPLVLEKLVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGNRAPVAVGVAAMSTAQMLASGLKGKGISVLHTYQDHLWRSGDKSSPPAIAPLDPTDSCEEKADLGLHGNLRSLSLEGEEENGQVPNPEASDDPNSRALSQDSVDGKPLQEQMDELLEQCFLHALKSRVKKADLPLLTSTLLGSHMFSCCPEGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFIVPEPSLASQTVQEGSREKPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRRIITDYAKRNNLVDADNRNLVKLDPILCDCILEKNEQHLVMKLPWDSLLTRCLKNLQPAYQVTFPGQEPIIKKGKLCPIDITLVLKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK
What is the function of this protein?
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner.  The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs.  Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety.  Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit.  In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2D, eIF2d, Ligatin.
What is the protein family that this protein belongs to?
Belongs to the eIF2D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_RHIME
Sequence: MSEVETSVEKHVFEADVAKLLHLMVHSVYSDKNVFLRELISNAADACEKLRYEAIVAPELLGSDPASRITLTLDEENARLVIEDNGIGMGRDELVESLGTIARSGTRAFMERIEAAQNKDGAQLIGQFGVGFYSAFMVADNVDVVSRRAGTDKAWHWASDGKGSYTVSAVDLADAPARGTRITLHLMDEAKTFTSRWTVERIVKEQSGHVPVPISIVEKPGAEPAQVADGTALWTKQKSEISKDDYTDFYRGVAGQYDEPALTVHFRAEGRHEYTALAFVPGSKPFDLFDPDRKGRMKLYVKRVFITDEAELLPRYLRFVRGLVDTADLPLNVSREMIQESPLLANIRKGLTNRVLTSIEKLAESDSEAFAKIWENFGSVIKEGIYEDFERRGQLLALSRFRTTADDDKPRALSDYVKEMKEGQSAIYYLTGDNLAQLKASPQLEGFRARGIEVLLLTCPVDSFWVTTAPDFDGKPFKSITQGAADLAGIAKNDDAAAASPEAGAAVTDFVSFARETLGEAVSDVRTSDRLTESAVCLVAPEQGPDRQLQKMLQDAGRIEGAPKPVLEINPGHQLIAALATCPSEDKAFREDAVKLLLDQARVLDGDRPEDPRAFAERLSRVFGRALKE
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BIFLO
Sequence: MATESTTNTTTIIARADQHDIDLHKASDRVNFGSIKEPIDVPYLLGVQTDSFDWLIGNERWKARVEEDEKNGTNTVAHTSGLDEVFNEISPIENFAQTMSLTFSDPYFEEPRHTVQECKEKDYTYSAPLYVNAEFENGDTGEIKSQTVFMGDFPLQTPHGTFIIGGTERVIVSQLVRSPGVYFDRQQDRTSDKEVFGAKIIPSRGAWLEFEIDKKDQPQVRVDRKRKQSAIVFLMAIGMTKSEIAQAFKDYPLVLDALEKETLETQDEALVDLYRKIRPADTPTPEAGKNLLDSFYFNTKRYDLARVGRYKINRKLGVEADFNDRSLHQEDIIATIKYLVALHDGAATFPGKRNGEDVDLRVDVDDIDHFGNRRIRQVGELIQNQLRTGLSRMERVVRERMTTQDAEAITPQSLINIRPVNATIKEFFGTSQLSQFMDQNNPLSGVTNKRRLSALGPGGLSRDRASMEVRDVHPSHFGRMCPIESPEGPNIGLIGSLATFGRVNPFGFIETPYRKVVNGHVTDEVEYMTADRDLDHVIAQANQELDENGNFVQKSALARVGEEEAVDVPVSSVDYMDVSPRQMVSLGASLIPFLEHDEGHRALMGTNMQRQAVPLIESERPLVGTGSEWRAANDSGDVIKSEKDGVVTYVSADLIRVMNDDGTTSSYKLAKFQRSNQTTCYNQRPIVHDGERVEAGSVMADGPAIQNGDLALGKNLLIAFMPWNGYNYEDAVIISQRLVQDDTLSSIHIEEYEIDARETKLGAEEITRDLPNVGEDAVANLDERGIIRIGAEVEAGDILVGKVTPKGETELTPEERLLRAIFGEKSREVRDTSLRVPHGETGTVIGVKEITREDAEEDGDELPNGVNQMIRVYIAQHRKITVGDKLSGRHGNKGCISRILPEEDMPFLADGTPVDIMLNPLGVPSRMNLGQVLELHLGWIAHSGWDISLDPNLEAEWKKLIPSGAEKAEPNTPVATPVFDGVKPEVLKGLLSTTLPNRDGDRLVGPDGKATLFDGRTGEPYTKPISVGYMYMLKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLHEMMTTKSDDVDGRVRVYGAIVKGDNLPPAGIPESFKVLLKEMQSLSLNVEVLNAEGVAIDMKDEDDDPASSADDLGFNIGARPDAAAKEDQKAEEPEYQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RS7_CUPNH
Sequence: MPRRREVPKRDVLPDPKFGNVEVAKFMNVLMLDGKKSVAERIVYGAFDQIEKKAGKAPIEVFSVAINNVKPVVEVKSRRVGGANYQVPVEVRPSRRLALAMRWLREAAKKRSEKSMALRLAGELLEASEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CH60_DECAR
Sequence: MAAKEVKFGDSARARMVEGINILADAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKFANMGAQMVKEVASKTSDIAGDGTTTATVLAQSIVREGMKFVAAGMNPMDLKRGIDKAVVATIAELQAFSKPCTTTKEIAQVGSISANSDSDIGEIIANAMEKVGKEGVITVEDGKSLANELDVVEGMQFDRGYLSPYFINNGDKQQALLENPFVLLFDKKISNIRDLLPILEQVAKAGRPLLIIAEDVDGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGTVIAEETGLTLEKAVLKDLGQAKRIEVAKENTTIIDGAGEAAAIEARVKQIRIQIEEATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRARAAVGKLKGDNHDQDAGIKIVLRAMEQPLREIVANAGDEPSVVVDKVQRGKGNYGYNASTGEYGDMVEMGVLDPTKVTRTALQNAASVAGLMLTTECMVAELAEDKPAGGMPDMGGMGGMGGMGGMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_AGRRK
Sequence: MAKADYYETLGVSRTADEKELKSAFRKLAMQFHPDKNPDDNDAERKFKEINEAYETLKDPNKRAAYDRYGHAAFEHGGMGGGGFGGGGFGGGGGFSDIFEDIFGEMMGGGRGRARSSGGRERGADLRYNMEISLEEAFTGKTAQIRVPTSITCDVCSGSGAKPGTQPKTCGTCQGSGRVRAAQGFFSVERTCPTCHGRGQTIPDPCGKCHGQGRITEERSLSVNIPSGIEDGTRIRLQGEGEAGTRGGPSGDLYIFLSVKPHEFFQRDGADLYCAVPISMTTAALGGTFDVATLDGTKSRVTVPEGTQVGKQFRLKAKGMPVLRSSQVGDLYIQIQIETPQKLTKRQRELLQEFEQISSKDNNPESTGFFARMKDFFDTFSD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_SERP5
Sequence: MIDTQALRAEQRLRASEVIRQDDFLVVPPAFIAGADVGFEQEGAVTRAAIAILRYPSLELVEYQVARVATTMPYIPGFLSFREYPALLAAWEQLHQKPDLVLVDGHGISHPRRLGVASHFGLLVNVPTIGVAKKRLCGKFAPLDEATDALAPLEDKGEQLGWVWRSKARCNPLFISTGHRVGADSALAWVQRCMAGYRLPEPTRWADAIASRRPAFQRWLQQHPEVSQ
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SALSV
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOE_ECO57
Sequence: MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNKVQPLIRR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma-E factor, RNA polymerase sigma-E factor, Sigma-24.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane via RseA.
Protein: EVG1_DROME
Sequence: MSRHRFNNVQIKALPGGLMAHHEPDADGGQPGSQKLPMWPSERIPPGGAGAFHSAKVQYSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEPPRPNTNNDPDKETLAILDRARNAKRKNLRQIEASGAYKQSYYRPPADNRMHGEKAKSQLQFTMAGTHLPDPAIKPRRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEIRDQIAERLRRIQALESKMKMKSNGGFRFVD
What are the official names of this protein?
UPF0193 protein EVG1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0193 (EVG1) family.
Protein: KMO_LEGPC
Sequence: MKHITIIGAGLAGTLCGLYLARRGYEVELFESRPDIRNSPTDYGRSINLALSCRGITALKAMNLLSEVNKIMVPMRARAIHEANGEVHYQPFGRHIDEYINAISRSDLNALLLNKAELCPNIKLHFNMKLHSLDIHNKKIKFENKNGDFVEASYHRLIGADGAPSHVRDMLKNEGIVSASRDFLSHGYKELSISKKHTKGMAREHLHLWPRDSFMLLGNPNPDDSITGSLFLANEGKDSFAELNNEEKLHLFFKTQFPDAYAAMPNLVQEFFGNPTGHLSTIQCSPWYYKDECLLIGDAAHGIIPFFGQGMNSAFEDCRILDELLDEYQDDWSRVTPVFYEQRKVNTDAIAKMSMDNYHEIHSDIRNPKFILQKQIERELMLRYPEHYVSMHVLVMFTNTPYAKAMAIGELQSGLLEQICFPITDIKELNWQEVEKLLSIYDKKLAKII
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Protein: RNM5_LACLA
Sequence: MVEKQKINEVIVVEGRDDTANLKRYFDCETYETGGSSIDDRDLERLKRLEDKRGIIVFTDPDFQGERIRKIIMQAVPNAKHAFLNRDEARPKGKGSLGVEHANFEALNQALAEVFGGEKVTDEFGSAKTQEPSSDRSSVSKKELLTELTQTDLMSFGLVMAADSRKRREFLCEQLRIGYANGKQIKKRLNMFKITKEQIENVMKNY
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5, RNase M5, Ribosomal RNA terminal maturase M5.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CHLCH
Sequence: MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVLSGIRFGKTIGSPIAMVIRNRDWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGFEDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIVTAIGSAKEEMPQQELAAMLAHGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQHNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGIEGSMSSGQVIHLRAAMKPISSLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVVAPVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LAN17_PROMM
Sequence: MSEEQLKAFIAKVQADTSLQEQLKVEGADVVAIAKASGFAITTEDLKAHQANSQKNLSDAELEGVAGGTIGGTIVSITCETCDLLVGKMC
What is the function of this protein?
Lanthionine-containing peptide (lantipeptide) with unknown function (Probable).  Does not show antibiotic activity against Lactococcus lactis 117 and Bacillus subtilis 6633 bacteria (By similarity).  Organisms that produce this peptide live in oligotrophic environments at very dilute concentrations, suggesting this peptide is not secreted to influence other bacteria (Probable).
What are the official names of this protein?
Lantipeptide prochlorosin 1.7, Lantipeptide Pcn1.7.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGD_STAAB
Sequence: MKQYKAYLIDLDGTMYMGTDEIDGAKQFIDYLNVKGIPHLYVTNNSTKTPEQVTEKLREMHIDAKPEEVVTSALATADYISEQSPGASVYMLGGSGLNTALTEAGLVIKNDEHVDYVVIGLDEQVTYEKIAIATLGVRNGATFISTNPDVSIPKERGFLPGNGAITSVVSVSTGVSPQFIGKPEPIIMVKALEILGLDKSEVAMVGDLYDTDIMSGINVGMDTIHVQTGVSTLEDVQNKNVPPTYSFKDLNEAIAELEK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
What are the official names of this protein?
Acid sugar phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NagD family.
Protein: MURI_SODGM
Sequence: MATRLQDGNSISPEPMLSDGSAAKRPTILVFDSGVGGLSIYNEVRQTLPNAHYLYVFDNEAFPYGEKPEQFIVDRVVAIVGAMWRQHKIDLVIVACNTASTISLPALRERFPCPIIGVVPAIKPAARLTRNGIVGLLATRATVQRSYTHDLISQYAGDCQILQLGTAELVDMAEARLHGELVPLPVLRKLLRPWLRAAEPPDTVVLGCTHFPLLSQELQAVLPEGTRLVDSGSAIARRAAWLVEHDMDVSSLQGETGPNKTYCLVTTPQAVALMPALTRYGFGSSGMLTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PSR1_YEAST
Sequence: MGFISSILCCSSETTQSNSNSAYRQQQSSSLNKNRSVKHSNTKSRTRGVHQTNSPPSKTNSAATFSSTERSTGKSGISTNDNEKKKPSSPTAAVTATTTNNMTKVEKRISKDDLYEEKYEVDEDEEIDDEDNRRSRGIVQEKGDAVKDTSRQKKQQQQQQQQSQPQPQPQSQSQSQSQSQSQQRGPTVQVSSDHLIQDMNLSRVSSSSQASETSNDADDEDDEDEEYIDLTLLQQGQYHAPGYNTLLPPQDESTKGKKCLILDLDETLVHSSFKYLRSADFVLSVEIDDQVHNVYVIKRPGVEEFLERVGKLFEVVVFTASVSRYGDPLLDILDTDKVIHHRLFREACYNYEGNYIKNLSQIGRPLSDIIILDNSPASYIFHPQHAIPISSWFSDTHDNELLDIIPLLEDLSVKTSLDVGKILDVTI
What is the function of this protein?
Has phosphatase activity in vitro.  Involved in the response to sodium and lithium ion stress (but not to potassium or sorbitol stress) by inducing transcription of the sodium pump ENA1/PMR2.  Acts through a calcineurin-independent pathway and is functionally redundant with PSR2.  Also involved in the general stress response; acts together with WHI2 to activate stress response element (STRE)-mediated gene expression, possibly through dephosphorylation of MSN2.
What are the official names of this protein?
Phosphatase PSR1, Plasma membrane sodium response protein 1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: SELU_SHEAM
Sequence: MSTNTVPAKQYREIFLKGHPIMDVRAPIEFSKGAFPNAVNLPLMTDSERQKVGTCYKEHGQEAAIELGHQLVAGKVKANRVDAWKAFFSEHPDGFLYCFRGGLRSRITQSWLKEVGLDIPFIEGGYKAMRQFLIDEIDTAPGKSEMLILSGITGSGKTDFVRLRSESVDLEGIANHRGSSFGRQHEGQPSQIDFENRLAIELLRHQEREQAKLLLEDESFLIGRNAIPKTFFEKMQQAPVLVLTSTLEERLPRLLDDYVHKMHAGYVERLGEEQGFIAYRDYLLGSLKGIYKRLGGKLHAEMTELMNKALATEQSRRDTSAHLDWISLLLESYYDPMYHYQLGKKAARVRFTGTHAEMHEYLSSLGK
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: HEM1_NITEC
Sequence: MQLFAFGVNHHTAPLDIREHVAFTEESMQHALHDLVGHQLVKEAAIISTCNRTEIYCNTDTPDKAVGWLADFHHLHSGDLEPYLYKLLREQAVKHAFRVASGLDSMVLGEAQILGQMKNAVKSAEQAGTLGLLLHKMFQHTFFVAKEVRTSTEIGACSVSMAAAAARLAERIFGNISEQKVLFIGAGEMIELCAAHFVAKRPVHVTVANRTVERAEALSRRFNAHPISLGELPDQLALHDIVVTSTASPLPILGKGMLERAIKLRKHRPIFIVDLAVPRDVEPEVAELDDVFLYYVDDLADIVREGLDSRQGAVTQAETIIDSNVMDFMHWVATRRSVPTIRALRDQAEQFRQHELSRAHKLLAKGEDPVKVLESLSSGLTNKFLHSPSSALNQVSNDEREQLVELVNRLYQLRYPR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ADA2C_CAVPO
Sequence: MASPALAAALLAAEGPNASGAGEGGGGVNASGAVWGPPPSQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAIISFPPLVSFYRQPDGAAYPRCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPEGESPTTENGLGAAAAAAAGENGHCAPPRADVEPDESSAAERRRRRGALRRGARQREAGVEAPGPGLGSAAADPGALSVSRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPTPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRSFKHILFRRRRRGFRQ
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2C adrenergic receptor, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HFQ_BACAH
Sequence: MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.