PharMolix/UniProtQA huggingface dataset:
Protein: KHSE_PICTO
Sequence: MIAISYSSSANLGPGYDILSMGHDAFYDEVEVLEDHSNGIRISGDGIPLDYKKNTAGLSASMILNDYGIKTGIKINIKKGIPAGLGLGSSGASAAAAVRAINKLFNLGMSHDEMVHYSMHGEIAACGSAHPDNVSSGIYGGITLVQSKNPVKIKKLKINLNFSILLVIPELFMENKTMYARSLVPSKITMDEHIESTQRLSSLISGLITGDRDLVSYGMNDNIVERARIKMFPYYYDLKRRVIENNAISACISGAGPTVLILYDDKSDYNGILRSVDDVMRSYNIKYILKKSRIMEAYND
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB1_GLOMM
Sequence: MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEVEEN
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SEC11_CLAL4
Sequence: MNLRQQLTQLLSIAYVFTSAFVAWKALSIVANSHSPIVVVLSGSMEPAFQRGDILFLWNRDSQAKVGDVVVYEIKGKSIPIVHRVLREHHGKDKQFLLTKGDNNALDDLSLYARKQNYLNQKTDLVGTVKAYLPKVGYVTILLTENMYFRYALLGFMGLSALLSGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: QUEF_ACIBT
Sequence: MSVEQSLLGKETQYPTSYQPDVLFPIARAQSREKYAHIEGITQGKDWWHVFEISWLNAHGIPQVAIGRITLPASSPNLIESKSLKLYFNSLNFTQFDSTQSFIETVEKDLSAAAGAKVELTLFQVDDLEISKPQGICIDDLMPERLEQHPDATLLKLDESDEEIEVELYSHLLRSNCPVTGQPDWGTVFIRFKGKKPCYRSILAYIISYRQHNGFHEQCVEQIFADIWQNLQPEKLMVYATYTRRGGLDINPCRVSDLTWMPKPIRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_STRP3
Sequence: MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAINPEKAVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGDTPLITGESLKSLIDFHVNHKNVATILTATAPDPFGYGRIVRNKDGEVIKIVEQKDANEYEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILRDFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFHNPETVYIESDVTIAPDVLIEGNVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPGTTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKYETVVGDHAFIGSNSTLIAPLEIGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAKRLAHHPSRSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_PYRFU
Sequence: MLTYAQAGVDEEKTSKALRFIIEAARKTFEFRKGKLGEPGDIGHYSALLDFGNYYLAITTDGVGTKVLVAEAVGKFDTIGIDMIAMNVNDLICVGAEPIALVDYFAIKEPNERVFEEVAKGLYKGAKEAGIAIVGGETAVMPDLVNGYDLAGTAIGIVEKDKVITGEKIRPGDAVIGISSSGIHSNGLTLARKLLIPKYGLDYEYESRKLWEWLLEPTRIYVKPILELLKSVEVHGLAHITGGGLLNLKRITNYGFRLNMPPINGIFKLIHENGVPLEEMFRVFNMGVGFVVVVSQEDKEEALQILNRYYESFELGTVSERPGIIVENYGVKFI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2065_YERPS
Sequence: MSQPPFWQQKTLAEMSDSEWESLCDGCGQCCLNKLIDEDTDEIYFTNVACDQLNIKTCQCSNYERRFELEEDCIKLTRENLVTFAWLPPTCAYRLIGEGHDLPRWHPLLTGSKAAMHGERISVRHIAVRESEVVDWQDHILNKPSWAK
What are the official names of this protein?
UPF0260 protein YPTB2065.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: FMP52_DEBHA
Sequence: MSAFIIGSTGLVGAQLLKVAAESNKFETVHTVSRRPVDGRDKVQGVVETDTAKWPEVIRENSKGVRTFFSAFGTTRADAGGVENFKKIDYGINYECAKAAKEAGIETFVLVSSLGANESSMLFYLKSKGKLENDIIALEFPRTIIIRPGALLGKRQKSQGIANEIFQKWGNMVKGTPFKFTAYPITGEEVAKVAVHLASEPLTQGDGPVVKAVGTSELDHLVKSLE
What are the official names of this protein?
Protein FMP52, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: PYRB_CORU7
Sequence: MKNLLSISDLTPNEILSIMDEADRFAEALKGREVKKLPTLRGRTVFTMFYENSTRTRASFETAGKWMSADVINISASSSSVKKGESLRDTALTLKSIGADALVMRHPSSGAAQHVANFIGDTAVINAGDGSNQHPTQALLDATTLRRQRGDLSGQHVVIVGDILHSRVARSNAQLLNALGADVTFVAPPTLLPIGVENWGVRVSHDLDAELPSADAVMMLRVQAERMNGGFFPSHREYATRYGLSKARHAMLKPDAVVMHPGPMLRGMEINYSVADAPNTVVLQQVTAGVHVRMAILFQLLIGGHSASETETDA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TRUA_SYNWW
Sequence: MSRIKLLLEYDGSNYHGFQLQKNANTVQAELEKAIYRLSGERATIVCAGRTDAGVHAWGQVVAFDSCSTIPGDRWAYALNSQLPEDIQVLESQETRAEFNPRFDALKKCYGYLIYRQKKKATFYRHYALCNTEPLKLEAMQEAAEILKGRQNFRSFCASGSSARTFEREIFHCRLSEKGPCLLLHIAADGFLYNMVRIITGTLLEVGKGKYPPQHLREIIASQDRTRAGPTAPPQGLYLLQVFYPEDSK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y5360_ARATH
Sequence: MASLKLGSKSEVFHLSGHTWLCKTGLKPDVMIQVVDESFHLHKFPLLSRSGYLETLFSKASETTCVAQLHDIPGGPETFLLVAKFCYGVRIEVTPENAVSLRCAAEYLQMSENYGDANLIYLTESFLNDHVFVNWEDSIKALEKSCEPKVLPLAEELHIVSRCIGSLAMKACAEDNTSFFNWPISLPEGTTTTTIYWNGIQTKATSENWWFNDVSSFLDLPMYKRFIKTVESRGVNAGIIAASVTHYAKRNLPLLGCSRKSGSPSEEGTNYGDDMYYSHEEQRSLLEEIVELLPGKKCVTSTKFLLRLLRTSMVLHASQVTQETLEKRIGMQLDEAALEDLLIPNMKYSGETLYDTDSVQRILDHFMLTFDSSIVEEKQMMGDSHPLKSITKVASLIDGYLAEVASDENLKLSKFQALGALIPEDVRPMDDGIYRAIDIYIKAHPWLTESEREQLCLLMNCQKLSLEACTHAAQNERLPLRVIVQVLFFEQMRLRTSIAGWLFGSEENNDTSGALEGNKNTNANMVMHGMRERVFELEKECMSMKQDLDKLVKTKEGRNFFSKIFGSRSKTKTSPCGKGGEDALVIPETKN
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Putative BTB/POZ domain-containing protein At5g13600.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: BYE1_CANGA
Sequence: MESLRKSSRSTKGKNTYLEVLRRQEEEEYEQRVNRPKKEKVQEIVHCSPCGTTDANYVEDEDPYGEMIQCDQCDTWQHINCMLQVKDIKVPKELENSDDVDSLSKLLVNSEDKYYCDRCIYKSQLREERRAYKELNKSEMIGDNDILDEPKEHPDEYVDDQDEDQDFILSKDTANIAEVDDDEFVENDDNRVKKDKRKRKPSNSAITTTKTVPKKKARVITDDQTETETIPSEDSYAKVRTNARKMLVTLFKNYIIPDTLKNNVFEIVKGHDEQSISDEFAEEMESKLFSHCRSISNYKTLISVYTEKVRVLFSNLKDPKNLSLKEAVINRQLDLEQLVSMSATDLANPDLQSMKKKIDSQKIDSLVIPNQPLDKLKQDNSEDDHNSFEFTNPTFTKTFNPKDIHESNSNNRPYTTDSPTNSYTDEPDSMKSDSNNGVDTNDQNILNVKFKLDYNEVDLNVVGTFKFLGSTLLDENQEHKIYQAVVGDGKLIYEGRLHTKIATEYISEIKTTRAVLAYQLLPSASHREKYEQLVEFMDDLDRVLGMKPRKPYVKNMYILSSLLGKLPDILQILTTDESIAKKRIDLSRINDNDKTLYLVVVVKPEIV
What is the function of this protein?
Negative regulator of transcription elongation.
What are the official names of this protein?
Transcription factor BYE1.
What is the protein family that this protein belongs to?
Belongs to the BYE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BENX_ASPTE
Sequence: MSAVEIPHPSGCRVYDIRQQAQGSMNLQTAITDGLLSTPKTLPSLLLWDAEGLRLFDEFAHSASYYLRDKELTILRDRSHEIVTVVPAQSILVELGSLQKTGRLIRALEKQQKPVRYYAVDVSLSGLTNSLTELRKELGDLHFVDITGLLGTYDDCVNWISNPSGQDPMSSPTVTFLWMGNSISNLNHYIDSSSLLSQFRLACDASRLRCQFLIAADACQDAQVVRTAYDAQNPTLRAFLLNGLSHANSVLGRAAFSPQDWSCESGFYPEQGQLEVYYVPLRDVELDVGGDRVYRVQRGERVRAISSGKWGKKLMGRVACAAGFQMNHAWGDSAGQYYFYHLYGGTQTFTSGNERVSVAHR
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of benzomalvin A and D (PubMed:28604695).  The pathway begins with the loading of amino acid precursors onto the A domains of the non ribosomal peptide synthetases benY and benZ (PubMed:28604695).  BenY and the A1 domain of benZ are loaded with anthranilate (Anth), while the A2 domain of benZ is loaded with phenylalanine (Phe) (PubMed:28604695).  N-methylation of Phe by the methyltransferase benX may happen before loading of Phe onto benZ, after loading of Phe, or after dipeptide formation (PubMed:28604695).  Condensation of Anth with the secondary amine of NmPhe or Phe is catalyzed by the C1 domain of benZ, forming a dipeptide intermediate (PubMed:28604695).  This is followed by in trans condensation of the Anth-NmPhe dipeptide with Anth bound to the T domain of benY by the C2 domain of benZ to form the linear tripeptide Anth-NmPhe-Anth (PubMed:28604695).  Cyclization and release of the tripeptide is then catalyzed by the C-terminal C domain of benY and the resulting 11-member macrocyclic intermediate is expected to spontaneously collapse to form the benzodiazepine core (PubMed:28604695).  Benzomalvin A is in conformational equilibrium with its atropisomer, benzomalvin D (PubMed:28604695).
What are the official names of this protein?
N-methyltransferase benX, Benzomalvin biosynthesis cluster protein X.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: KTHY_ACIAC
Sequence: MQRRGWFITFEGIDGAGKSSHIEAVAEALRREGRTVTVTREPGGTPLAETLRSLLLNEAMDALTESLVVFAGRRDHLRSVIAPALVRGEVVLCDRFTDATFAYQGAGRGFDRAVLAQLERITQSGLQEGTDAVLHPHLTLWFDLAPDVAAARLEGARAPDRFEAQPVEFFRRVAQGYADRAAADPGRFARLDADQPREAVRAQLMEILHRRGVLDAAQEGG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GLGB_STRGC
Sequence: MDKNEALRTFTTGENFHLQHYLGAHQEEVDGKVGYSFRVWAPNAQSVHLIGDFTNWYENQIPMARNEAGVWEVFTDLPKEGDIYKYNVKRSSGQEILKIDPLAVYLEERPGTGAVIRTIPEKKWKDGLWLARRKRWGFFSRPVNIYEVHAGSWKRNEDGSPYSFAQLKEDLIPYLVEMNYTHVEFMPLMAHPLGLSWGYQLMGYFAFEHTYGTPEEFQDFVEECHLNNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHDRAHNYGWGALNFDLGKNQVQSFLISSIKFWIDFYHLDGIRVDAVSNMLYLDYDSGPWQPNKDGGNRNYEGYYFLQRLNTVIKLAHPDVMMIAEESSSGTKITGMRELGGLGFDYKWNMGWMNDILRFYEEDPIYRKYDFNLVTFSFMYVFSENFLLPFSHDEVVHGKKSLMHKMWGDRYNQFAGLRNLLTYQICHPGKKLLFMGSEFGQFLEWKSEEQLEWSNLDDEMNKKMQGFTATLNAFYKDNRPLWEIDLSYDGIEIIDADNVDQSVLSFIRKTEKGDMLICVFNMAPVERKNFTIGVPVAAVYEEVWNTELEEWGGVWKEHNETVQSQEGLWKDYPQTLTFTLPALGASIWKIKRRIKSKSTKNKK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: GGGPS_METLZ
Sequence: MNWQTWRHITKLDPDKVITKEEIAEIAASETDALMLSGTLDVTPENLAELYDNVRDAGLPLTVEPADPSCARFEGIDYVFVPSVFNAGHPAFITGLHKEWAQHADILWDKVVQEAYVVLNPNSSVGKLTRAKCDLTPAEVAAYGIVAEKYYSMPVLYIEYSGMYGDPAVTRAVSEALSTTRVFYGGGINSGAKAAEMGQYADTIVVGNAVYEAGPAVLKETVKAVK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_ALIF1
Sequence: MRLIPLNRAEQVGAWSAQHIVNRINAFNPTADRPFVLGLPTGGTPLNTYKKLIELHKAGEVSFKNVVTFNMDEYVGLPADHPESYRTFMHENFFNHIDIQPENINLLNGNAEDHEAECQRYEDKIKSYGRINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFGGDMNLVPEYSLTIGVGTLLDSEEIMILITGHNKGLALQAAVEGSVNHLWTVSALQLHPKSVIVCDEPSTQELKVKTVKYFQQLEAKNMEGF
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: TDH_CALS4
Sequence: MDGLMTAVVKQYHKEGADIVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVGEVVEIGENVTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLILGVDTDGAFAEYIKVPESNVWINDKNIPLEILSIQEPLGNAVHTVFSGDVVGKSVAVIGCGPIGMMAIPLLKRTGAAAIFAIEPADYRRELAHKLGATRVINPLREDVVSIIKSETEGYGADVVLDFSGNPTAIRQGLEYIAKGGRMSILGLPDNEVPIDITNNVVFKGITIQGITGRRMYDTWYTVKGLLKSGLAEDLKPIITHTFPLTEYQKGMELMIKGQCGKVVLYP
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BHMT1_DANRE
Sequence: MAPVGSKRGVLERLNAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAAEHPEAVRQLHREFLRAGSNVMQTFTFYASDDKLENRGNKLSFTGQQINEAACDLAREVANEGDALVAGGVSQTPSYLSCKSEEEVKKTFKKQLDVFIKKNVDLLIAEYFEHVEEAEWAVQVLKATGKPVAATLCIGPDGDMHGVIPGECAVRLVKAGADIVGVNCHFDPLTCVKTVAMMKAAVEKAGLKAHYMTQPLAYHTPDCSCQGFIDLPEFPFALEPRILTRWEMQQYAREAYKAGIRYIGGCCGFEPYHIRAVAEELSAERGFLPEASQKHGLWGSGLEMHTKPWVRARARRDYWEKLKPASGRPLCPSMSTPDGWGVTRGHAALMQQKEATTAEQLRPLFQQADAKH
What is the function of this protein?
Involved in the regulation of homocysteine metabolism.  Converts betaine and homocysteine to dimethylglycine and methionine, respectively.  This reaction is also required for the irreversible oxidation of choline (By similarity).
What are the official names of this protein?
Betaine--homocysteine S-methyltransferase 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP12C_MOUSE
Sequence: MSGEDGPAAGPGAAAAAAAARERRQEQLRQWGARAGADPGPGERRARTVRFERAAEFLAACAGGDLDEARLMLRAADPGPGSGAASDPAVPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESDAMEGLLKAEITRRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDTELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEDVMNLLEELAQKQEDLRNQKEGSQGRGQESQVPSSSKHRRSSVCRLSSREKISLQDLSKERRPGGAGGPPIGDEDEGGEASAEHPAVEPRALNGVSSPVSSNPKSPVLPEEAPFSRRFGLQKTGSTGALGPSERRATEGVLGLQRSASSSLLEKASTQAREPRLARITPTPAQKVPEPFTLYEAATPPSLDHSVPPSRREPGSIVKPNVLTASAAPLADSRDRRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKVAGKVPEPEQPALPSLDPSRRPRVPGVENAEGPAQREAPEGQGQGPQAAREHRKAGHERRGPAEGEEAGPAERSPECSTVDGGSQVRRQHSQRDLVLESKQEHEEPDGGFRKMYTELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK
What is the function of this protein?
Regulates myosin phosphatase activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12C, Protein phosphatase 1 myosin-binding subunit of 85 kDa, Protein phosphatase 1 myosin-binding subunit p85.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, stress fiber.
Protein: SGMR1_XENTR
Sequence: MALWRGLRAVLAVAGLAVAVQLLRGWLGSKSYVFNREEIARLAKEHSGLDYEVAFSKIITELRKKHPGRILPDEDLQWVFVNAGGWMGSMCLLHASLTEYVLLFGTAVDTSGHSGRYWAEISDTILSGTFRQWKEGSTKSEIFYPGDTIVHEVGEATSVQWSAGTWMVEYGRGFIPSTLGFALADTIFSTQDFLTLFYTVKVYGKALLLETSTHLSELGFF
What is the function of this protein?
May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane.  May regulate calcium efflux at the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Sigma non-opioid intracellular receptor 1, Sigma 1-type opioid receptor, Sigma1-receptor, Sigma1R.
What is the protein family that this protein belongs to?
Belongs to the ERG2 family.
What are the subcellular locations of this protein?
Nucleus inner membrane. Nucleus outer membrane. Nucleus envelope. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Membrane; Single-pass membrane protein. Note=During interphase, detected at the inner and outer nuclear membrane and the endoplasmic reticulum. Detected on cytoplasmic vesicles during mitosis (By similarity). Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum (By similarity).
Protein: PA2A3_VIPRE
Sequence: MRTLWIVAVCLIGVEGNLFQFGKMIKYKTGKSALLSYSAYGCYCGWGGQGKPQDPTDRCCFVHDCCYGRVNGCNPKMDTYSYSFLNGDIVCGDDDPCLRAICECDRAAAICFGENVNTYDKKYKYYSSSHCTETEQC
What are the official names of this protein?
Acidic phospholipase A2 Vur-PL3, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAA_SALCH
Sequence: MKHLHRFFSSDASGGIILIIAAALAMLMANMGATSGWYHDFLETPVQLRVGALEINKNMLLWINDALMAVFFLLIGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYSDPVTREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIVIIALFYTSDLSIVSLGVAAFAIAVLALLNLCGVRRTGVYILVGAVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTIDGLTSMLPLGIIAGLLIGKPLGISLFCWLALRFKLAHLPQGTTYQQIMAVGILCGIGFTMSIFIASLAFGNVDPELINWAKLGILIGSLLSAVVGYSWLRARLNAPA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BL1S4_YEAS1
Sequence: MQDNSSHSRESASAGDDPLGIDKLTVDYDYLLYKIRDYVQSIQLDTTELCKKQNEVMVNGIIENTIDKNIAKFKELLEKCDTLENHYEMLNQLAIITDTFKERIAEAVNNYNSLKKGASKSK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit CNL1, BLOC-1 subunit CNL1, CNO-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S4 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Punctate pattern.
Protein: ACPH_RAT
Sequence: MERQVLLSEPQEAAALYRGLSRQPSLSAACLGPEVTTQYGGLYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGGTVSGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDISASDDEMARPKKPDQAIKGDQFVFYEDWGETMVSKSIPVLCVLDIDSGNISVLEGVPENVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDGSLAICSPRLSPDQCRIVYLQYPCLAPHHQCSQLCLYDWYTKVTSVVVDIVPRQLGESFSGIYCSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDTQTGSITSLTAAGSAGSWKLLTIDKDLMVAQFSTPSLPPSLKVGFLPPPGKEQSVSWVSLEEAEPIPGIHWGVRVLHPPPDQENVQYADLDFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHFDARRVALMGGSHGGFLSCHLIGQYPETYSACIARNPVINIASMMGSTDIPDWCMVETGFPYSNSCLPDLNVWEEMLDKSPIKYIPQVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSNHALSEVEAESDSFMNAVLWLHTHLGS
What is the function of this protein?
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus (PubMed:3305492).  It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (PubMed:3305492).  Also, involved in the degradation of oxidized and glycated proteins (By similarity).
What are the official names of this protein?
Acylamino-acid-releasing enzyme, AARE, Acyl-peptide hydrolase, APH, Acylaminoacyl-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_PASMU
Sequence: MFDAKSFLANVSHDAGVYRMYDEKDTVIYVGKAKDLKKRLSSYFRTHLSSKKTEALVSAIARIDTTITSSETEALLLEHNYIKTYQPRYNVLLRDDKSYPYILLTAERHPRISAYRGSKKIKGEYFGPYPHASAVRETLSLLQKLFPIRQCENAVYNNRSRPCLQYQIGRCAAPCVAGYVTDEAYLQQVELARLFLQGKDQQVLEHLIHKMEQASLALDFEEAARIRDQIQAVRAVMEKQFVSTERLDDMDILSIAYQLGIACVQVLFIRQGKMLGNRSYFPKVPANTTLSELTATFVGQFYLQAHQGRSIPHRIIVDHKLSEKTELEELLTQQAGRKVHIQDNTKGEKSKYLQLAKMNAQSALVTQLKQSTLLKERYQALQAILQLGEIRRMECFDISHTMGEQTIASCVVFNQDGPLKSDYRRFNITGITAGDDYAAMEQALLKRYDKPLEQEKIPDVIFIDGGKGQLNRALQTFSKLNVKWDKNQPHLIGVAKGIDRKAGLETLILSKQGKILHLPSDHLALHLIQHIRDESHQHAISGHRKKRQQAFLQSGLESVEGVGAKRRQTLLKYLGGMQGVKKATLDEIASVPGISKALAERIYDALRD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.