PharMolix/UniProtQA huggingface dataset:
Protein: SRP54_SCHPO
Sequence: MVFADLGRRLNSALGDFSKATSVNEELVDTLLKNICTALLETDVNVRLVQELRSNIKKKINVSTLPQGINGKRIVQKAVFDELCSLVDPKVDAFTPKKGRPSVIMMVGLQGSGKTTTCSKLALHYQRRGLKSCLVAADTFRAGAFDQLKQNAIKARVPYFGSYTETDPVVIAKEGVDKFKNDRFDVIIVDTSGRHQQEQELFAEMVEISDAIRPDQTIMILDASIGQAAESQSKAFKETADFGAVIITKLDGHAKGGGALSAVAATKTPIVFIGTGEHINDLERFSPRSFISKLLGLGDLEGLMEHVQSLDFDKKNMVKNLEQGKFTVRDFRDQLGNIMKLGPLSKMASMIPGMSNMMNGMNDEEGSLRMKRMLYIVDSMTEQELDSDGLLFVEQPSRVLRVARGSGTSVLEVEETISQVRVFAQMAKKIGGKDGILGKLGGNPAAALKKDPRQLAAMQKRMQAMGMGGGMPGLNPGSMNFGDISKMANMLMGGGGPGGAGGMDFSGMLNQFQNMQKPPRRR
What is the function of this protein?
Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane.  SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences.  It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting.  srp54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes.  srp54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101.  Both, srp54 and srp101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon).  After signal sequence transfer, srp54 and srp101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.
What are the official names of this protein?
Signal recognition particle subunit SRP54, Signal recognition particle 54 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_HELHP
Sequence: MEKYSFESVQELSLRPNVWEEYIGQEKIKKNLKVFIEASKKRKECLDHILFFGPPGLGKTTLSHIIAHEMGCNIKVSAAPMIEKSGDLAAILTNLNEGDILFIDEIHRLSPAIEEILYPAMEDFRLDIIIGSGPAAQTLKIDLAPFTLIGATTRAGMLSNPLRDRFGMSFRLQFYEPKELSAIVICASSKLGRSLSKSGADEIARRSRGTPRIALRLLRRVRDFADVGEYAQDMRNQSEISLECVRYALNELGVNELGFDELDLRYLAILAESRGKAIGLNTIAAAMSEDEATIEDVIEPYLLANGYLERTAKGRVASPKTYELLHIPFLEQKGLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: BCAP_BACSU
Sequence: MKGSVFRKKSIQDLIAATSGEKSLKRELGAFDLTLLGIGAIIGTGIFVLTGTGAVTAGPGLTISFVVAALACLFAALSYAEFASSVPVSGSVYTFTYATLGELMAFIIGWDLILEYMLAVSAVSVGWSGYFQSFLSGLGIHLPVALTAAPGAVKGTFTLFNLPAFVIVMAITYLLYLGIKESKRVNNIMVILKILVVLLFIAVAAVYVKPHNWQPFMPMGFGGVFSAAALVFFAFIGFDAVSSAAEETKNPAKDLPKGIIFSLLVCTILYVTVSAIMTGVIPFAQFAGVDHPVSLVLQSAGQNWVAGIIDIGAVLGMTTVMLVMLYGQTRVMFAMSRDGLVPGSLSKVHPKHKTPYVATWFFGTMSALLGSLVPLDELAKLVNIGTLSAFVLISVAVIVLRKKQPDLPRAFKCPGVPVIPGLAILFCLFLILNLGWVTIVRFLVWLLIGLVIYFLYSRKHSKLNQ
What is the function of this protein?
Branched-chain amino acid transport system which is involved in the uptake of isoleucine, valine and probably leucine (PubMed:25645558).  Can also transport threonine, and is active as a minor serine permease (PubMed:25645558, PubMed:32743959).  May be an amino acid permease of rather broad specificity, because several amino acids, albeit at 100-fold excess, are able to prevent isoleucine uptake (PubMed:25645558).  Probably does not transport methionine (PubMed:25645558).  Together with BraB and BrnQ, plays an important role in the activation of CodY, a branched-chain amino acid-responsive transcriptional regulator that controls the expression of several dozen transcription units in B. subtilis (PubMed:25645558).
What are the official names of this protein?
Branched-chain amino acid permease BcaP, BCAA permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
Protein: GSA_MYCS2
Sequence: MAMRVDQTCGSEEHSPASTQRSAQLFADACAVIPGGVNSPVRAFNSVGGTPRFITSAGGYWLTDADGNRYIDLVCSWGPMLLGHAHPAVVEAVRKVAEHGLSFGAPTPSETELAAEIIDRVAPVEMMRFVNSGTEATMSAIRLARGFTGRAKIVKFSGCYHGHSDALLADAGSGVATLGLPSSPGVTGAAAADTIVIPYNNVAAVEDVFAHFGDEIACVISEASPGNMGTVPPLPGFNAALRRITAEHGALLILDEVMTGFRVSRSGWYGLDPVEADLLTFGKVMSGGLPAAAFGGRTEVMSRLAPLGPVYQAGTLSGNPVAMAAGLTTLRHADDAVYAKLDANADRLAGLLTGALTEAGVAHQVQRAGNMLSVFFTDAPVHDFAAAKATETWRFPPFFHALLERGVYPPCSAFETWFVSAALDDDAFARIAEALPAAARAAAAATPEGTA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_SHEWM
Sequence: MSATYNFCAGPAMLPQAVMEKAQSELLDWNGLGTSVMEISHRSKEFIALTEQAEIDLRELMSIPSNYHVLFMHGGGRGQFSAVVNNFLGNNGKALYLVDGSWSSAAVDEAKKLAGETQIDTLNIVEKDGATSRVSIPNLKELDQDYRYLHYCPNETVDGIEIFEELDSPWPIVADMSSNIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVKDELLQLPQLPQSSIMDYRLGVKHGSMYNTPPTFAWYLAAEVFKWLKSSGGVGEVQKANERKAGTLYQFIDSCDFYENRVAVENRSVMNVTFYLKDEALNDEFIKQAKAVGLVALKGHRSVGGMRASIYNAMPLEGVEKLVEFMTDFANKNRA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_PROM9
Sequence: MDITAISLVLFGSTFGLIFRMFIQNNLKINIGFNIQNTSIVNFIASFFLGILLALNLTNNNLLLLFYIGFLGCFSTFSSFIYQLFVLLQKRKFMHLFFHYFEVIIISFICFYLGYYLMQIIK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS8_THESM
Sequence: MTLLDPLANALSHITNSEKVGKSEVYIKPASKLIGEVLRVMQENGYIGEFEFIDDGRAGIYRVQLLGKVNKAGAIKPRFSVKAKEYEKWEKRFLPAFEFGILVVSTSQGVMTHKEALEKGIGGRLIAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: BGL1A_PHACH
Sequence: MSAAKLPKSFVWGYATAAYQIEGSPDKDGREPSIWDTFCKAPGKIADGSSGDVATDSYNRWREDVQLLKSYGVKAYRFSLSWSRIIPKGGRSDPVNGAGIKHYRTLIEELVKEGITPFVTLYHWDLPQALDDRYGGWLNKEEAIQDFTNYAKLCFESFGDLVQNWITFNEPWVISVMGYGNGIFAPGHVSNTEPWIVSHHIILAHAHAVKLYRDEFKEKQGGQIGITLDSHWLIPYDDTDASKEATLRAMEFKLGRFANPIYKGEYPPRIKKILGDRLPEFTPEEIELVKGSSDFFGLNTYTTHLVQDGGSDELAGFVKTGHTRADGTQLGTQSDMGWLQTYGPGFRWLLNYLWKAYDKPVYVTENGFPVKGENDLPVEQAVDDTDRQAYYRDYTEALLQAVTEDGADVRGYFGWSLLDNFEWAEGYKVRFGVTHVDYETQKRTPKKSAEFLSRWFKEHIEE
What is the function of this protein?
Plays an important role in cellulose degradation.  Shows hydrolytic activity against several glycosidic compounds.
What are the official names of this protein?
Beta-glucosidase 1A, Cellobiase 1A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: TMPS5_HUMAN
Sequence: MSLMLDDQPPMEAQYAEEGPGPGIFRAEPGDQQHPISQAVCWRSMRRGCAVLGALGLLAGAGVGSWLLVLYLCPAASQPISGTLQDEEITLSCSEASAEEALLPALPKTVSFRINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSLL
What is the function of this protein?
May play a role in hearing.
What are the official names of this protein?
Transmembrane protease serine 5, Spinesin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: KDPB_POLAQ
Sequence: MTKRKLGMFDAELVKPAIVDSFRKLSPSIQWRNPVMFVVYIGSILTTLLWIQSLYGEGEASSSFILGVMLWLWFTVLFANFAEALAEGRSKAQAASLRGLKKETWAKKVKAANIPENWDNRPASELVSATQLRKGDIFIAEANDVIAADGEVIAGVASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWIVVRVTVNPGETFIDRMISMVENAKRQKTPNEIALTILLVALTIVFLVVVATLLPFSMFSVAASGSGSPIQITVLIALLVCLIPTTIAGLLSAIGVAGMSRMMAANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASNFVAASGVTEAELADIAQLASLADETPEGRSIVVLAKQKFNIREREINSIGAQFVPFTAQTRMSGVDMNGEQIRKGAASAIQKHIESLGGHFPQEVLKAVDDVSRRGSTPLVVSQGTRVMGVVELKDIVKGGIKERFNELRQMGIRTIMITGDNKLTAAAIAAEAGVDDFLAEATPEDKLALIRKHQSEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVETGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFVATYPQLEALNVMHLSSPSSAILSAVIFNALIIIFLIPLALKGVTYKPLGAAALLRRNMTIYGLGGLIAPFIGIKIIDLIISVI
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF2_MYCBO
Sequence: MDPDRQADIAALDCTLTTVERVLDVEGLRSRIEKLEHEASDPHLWDDQTRAQRVTSELSHTQGELRRVEELRRRLDDLPVLYELAAEEAGAAAADAVAEADAELKSLRADIEATEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPFAYGTLSVEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVVETTDHIDIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPSGIVVTCQNEKSQLQNKIAAMRVLQAKLLERKRLEERAELDALKADGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPAAVLDGDLDGFLEAGIRWRNRRNDD
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MO4L2_PANTR
Sequence: MSSRKQGSQPRGQQSAEEENFKKPTRSNMQRSKMRGASSGKKTAGPQQKNLEPALPGRWGGRSAENPPSGSVRKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKSQGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A.  This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.  This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.  The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400.  NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.  Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones (By similarity).
What are the official names of this protein?
Mortality factor 4-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPM_CORAP
Sequence: MDAIKKKMLAMKMEKENALDRAEQVEQKLRDCECNKNKVEEDLNNLQKKFAILENDFDSINEQLLDANTKLEASEKKNAEIESETAGLQRRIQLLEEDLERSEERLQSATEKLEEASKAADESERGRKVLESRSLADDERLDGLEAQLKEAKYIAEDAERKFDEAARKLAITEVDLERAEARLEAAEAKILELEEELKVVGNNMKSLEISEQEASQREDSYEETIRDLTQRLKDAENRASEAERTVSKLQKEVDRLEDELLAEKERYKATSDELDSTFAELAGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: YVF3_AGRT9
Sequence: MARCSCLIPAAWFRRIICSFTPPLRAPMIVDILVRFRIPVFSAWRGPCSPSTRDRGDDHLADRWKSVLLIIASIACGWIGWSGEVLLLPPAMFFPLLWAMAPSRTIATLVAVGYFLAACRGLPQGVANFYATDLWPRLVLWAVASVSVND
What are the official names of this protein?
Uncharacterized protein outside the virF region, ORF3.
What is the protein family that this protein belongs to?
To A.tumefaciens conjugal transfer protein TraB.
Protein: ERPA_ENT38
Sequence: MSDDVALPLQFTEAAAKKVKVLIADENNPELKLRVYITGGGCSGFQYGFTFDDQINDGDMTIEKQGVALVVDPMSLQYLVGGAVDYTEGLEGSRFVVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: DCL21_ASPNC
Sequence: MTVAATVLPAGEDAPAYRPRSYQVEMFEASLKENIIVTMGTGSGKTHIALLRIIKELESNPHKLIWFLTPTVALCLQQFKFLSDNIPAVRARTLTSLDKVELWTEQPVWDAILKEMQVVVSTHAVLADAMSHGFVKITQLGLMIFDEAHHCMRRHPANKIMQDFYHPALERHGAEAVPKILGLTASPVVRSNRQELLKIESNLDAVCKTPRTHRSELMTHTHRPHLQQILFTPVLLDDLQVGSKTLKALVSAWTSLRLEDDPYIKKLRKSPLDGRALQKVLESGKTYCNDQLKRFATRSLHIFEELGEWAADYFIHASIEQLKARAGNSADTMGWTDEEKAYLLDIVSKLPIPNIDLTHSDPDRIPISSKFRSLLEFLDTKGEPNFSGLIFAKQRATVSVMEKLLSIHPVTKHRFRCASFVGWSGGGSKDVLGELLDARMQRDTLSEFRTGQKNLIIATDVLEEGIDISACSVVVCFDKPPNLKSFVQRRGRARHRQSTYAIMFATDDESSALSKWEDLEQAMIEAYEDDERRLREAWALEAINEEVVERLEVQSTGAVLTADTAVAHLNHFCAVLPRQPYASNEPEFSYEKDDADLLRGTVTLPSCVHPGVRRIQGQRWWQTERAARKEAAFQAYKRLYEFGLLSDHLLPFKRNLELKETDLTNLPALVEVSEQYDPWVDWACSWSSPDVHQTRIAIKHNGDSRMCIRLTSPTSLPPVEPMTLFWDSETIYTLDFDKPKRMKEIAAESIENMRLATALYLQAASSRQMRPEQDFVTLFGPDLTDLELAEWLNKHAGDEPALEVYSRKDFPTVMGIVRDRSRYNEPMLFKRWVVSGQDDTPIVELECDAVPKRRNLLHRQTLAAKQPDSETPAISSKIRLILAENCTIDKLPYAETIFGRFISVILDRLEATLVATRLCETILRDLEFSSIRHIITAITAPSAQSLTNYQRYEFFGDSVLKFTVSCQLFFQHPNWHEGYLSEGRDEIVQNSRLARAALDAGLDAFIMNKMFTPRKWSAPLISEKISLTPKQRTMSTKVLADVVEALIGASYIDGGFAAAHACIHRFLPEVNLENIDRTTAPMPKDGVTNHTLNDDHLMAHIGYTFTNKSLLVESLTHPSCQFDTTTQSYQRLEFLGDAVLDMAIMSTLLSHPREIPQGLMTKIKHAVVNANLLAFFCMEFALTEKRTNVQVTPTGTVTLNPSTEHIELWRFMRYQGAHLQTARDLALSRHSSLRGSIIHGLKHSPSYPWKSLSQLNADKFFSDIIESILGAIFIDSHGNLAECEKFLERLGLLRYLRRILKDEVDVMHPRNIAQQMAKGEIRFEVLRVPNEGGGGGEDDGATYRCTVKMAGVDGVAVVVEGCLTSEEAEITAAERAVEILVGRGCSL
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 2-1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: MFD_STAAN
Sequence: MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKYAQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERIRTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGYKRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNIEEVDITTASDYIITEEVIRHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDHQILRRLVAFMYETPSTIIEYFQKDAIIAVDEFNRIKETEESLTVESDSFISNIIESGNGFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMRSEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLSEGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGVGRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGSEWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQAKSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKDLGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIAVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTEYIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHSGITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQWLDSLKFLVKCIEESMRISDEA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_METTH
Sequence: MMEFLMVFIISTVSAAVFTLFIRNILRSADIGDKPIVTEHSHKAGTPTMGGLGMLLALLLVTVLYRNNPYLVLTSLIVLTAAIVGLLDDLLGLKVKEVQRIIRNVSEGPLEVGQLVLKPGEEARAATDKAKRDVEALLSEGLVEVVGEAPIKNEVSEGEKILAQLLIGVFLVLSGAVGKLGGFYLGLAAAPIAIAGMVGAINAVNLIDGMDGMAAGIMLIASLSCAIFLGLSGQALPFLALAGMCAGFLVFNRHPASIFMGDTGSFALGAGYATAVMLTDTVYFGVLAIAVPVVSVIVSLLHRAGVIRLPVEPLHHTLHYRGMSERRIVLLYWLITLIVCALGLYMTGSIL
What are the official names of this protein?
Putative phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_MOUSE
Sequence: MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: OBG_HYDS0
Sequence: MNFIDIAQIKVKAGDGGNGGVYFLREKYRPYGGPAGGDGGKGGSVILQADSSKTTFLDFKYKRHFVAQNGEHGKPKNQHGKNGKDIVIKVPVGTIVIDKKTNDVLCDLVKHGQSCVVAKGGDGGLGNAHFATPTNQTPRKFTHGKKGEEKELILILKTIADIAIVGLPNVGKSTLLLVLTNAHPKIADYPFTTLYPELGVIKTDDKSFTIADIPGIIENAHKGAGLGLDFLKHIERSKYLVLAIDLSSENPVKDFEILITEIYLYDKSLIQKVKTIVGTKLDIAKKENLELLEKLAKEKSLDFIPVSSTTGQNIEYLKEYITNLMNH
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_CANTT
Sequence: MSISKYSIRFLSDKATRFVPKSGVYPKGYAVGGIHCGVKKDGKSLDLAILQNTFNKEASTAGVFTQNKFKAAPVQVSMRILKQKSGSGINSFVINSGNANAVTGSKGMKDAEEMVTVTDSVLENPKDSTLVMSTGVIGNNLPIDNILTGIPKLSLNHLGNTHQHWIDCATAICTTDTFPKLVTKQFNLGNDTYTLAGLCKGAGMICPNMATLLGFFVTDAPVSPNALQQILRYAVDRSFNSITVDGDMSTNDTIVAMANGAAGGELIDNTSSSAERFSALQTEIVDFAQQLAQLVVRDGEGATKFITLKVNDALSYKDAKSIASSIANSSLFKTAMYGKDANWGRILCAIGYADVSTDQSVIPNKTSVKFVPVDGSEPIKIIWLMVNSKKLTKIELQKYYKMKIW
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL23_NITOC
Sequence: MNEERLTKVILAPVISEKSTLVGEKHNQVIFKILSDADKREVKQAVELLFDVKVTKVHTALVKGKRKRSGRYIGRRSNWKKAYVALQEGYEIDFASVE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SFSA_VIBPA
Sequence: MQFKPALESATLLKRYKRFLADIEFDNGEVRTIHCANTGAMTGCATPGNKVWFSTSDNPKRKYPNSWELSETEQGHRICINTARANQLAVEAIENNVISELCGYDTLQTEVKYGNENSRIDILLSASDKPKCYIEVKSVTLLDETGSAGQGYFPDAVTTRGQKHLRELTEMAQNGSRAILLFTVLHSGIEKVSAAHHIDAKYSLLLKQAQDAGVEVLCYKAELSNTEMKLISAIDFIN
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.