PharMolix/UniProtQA huggingface dataset:
Protein: O10S1_HUMAN
Sequence: MTSRSVCEKMTMTTENPNQTVVSHFFLEGLRYTAKHSSLFFLLFLLIYSITVAGNLLILLTVGSDSHLSLPMYHFLGHLSFLDACLSTVTVPKVMAGLLTLDGKVISFEGCAVQLYCFHFLASTECFLYTVMAYDRYLAICQPLHYPVAMNRRMCAEMAGITWAIGATHAAIHTSLTFRLLYCGPCHIAYFFCDIPPVLKLACTDTTINELVMLASIGIVAAGCLILIVISYIFIVAAVLRIRTAQGRQRAFSPCTAQLTGVLLYYVPPVCIYLQPRSSEAGAGAPAVFYTIVTPMLNPFIYTLRNKEVKHALQRLLCSSFRESTAGSPPP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10S1, Olfactory receptor OR11-279.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAAT_HUMAN
Sequence: METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVILKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVLDDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPALGSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQNPNSPPTGIPLRHYDSGERLSNGER
What is the function of this protein?
ATPase that regulates mitochondrial ABC transporters ABCB7, ABCB8/MITOSUR and ABCB10 (PubMed:25063848).  Regulates mitochondrial ferric concentration and heme biosynthesis and plays a role in the maintenance of mitochondrial homeostasis and cell survival (PubMed:25063848).
What are the official names of this protein?
ATPase PAAT, Protein associated with ABC transporters, PAAT.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: GLNA_METTH
Sequence: MSDKIGRIIAKMDECGVKFVRLQFVDIHGKPKNMAIPLVRPDQIEDIIKDGLLFDGSSVEGFVDINESDLVLKPDPDTFSTLPWRPEEKGVCRFICDIYWPDGKPFEGDPRYVLKRALDKYAHLGYEYNVGPEPEFFILDQDEDGNIIPHDCGAYFDVEPVDQGTDFRRKLVMDLEALNFDVEVSHHEVAPGQHEIDFKFDKALKTADAVITFKQAIKAIVDKIGYMVTFMPKPFFGENGSGMHCHQSLFKDGENVFYDPDTETQLSEEALYFIGGLLKHAPALTAVCAPTVNSYKRLVPGYEAPVYIAYGLKNRSTLIRIPASRGKGTRVELRMPDPSCNPYLAFAAMLEAGMNGIQNKIDPGEPTEIDVYEKSMSELREMGIETLPSSLWEAYHALEEDDVIKGALGGHVYEKFMEIKHREWDDYRVRVFKYELERYLDI
What is the function of this protein?
Probably involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_ALISL
Sequence: MANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSVYDLGCSLGAATLSMRRHINQEGCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRDVNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGILILSEKYIFEDGVVNELLIDLHHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: HYFF_METI4
Sequence: MSAAAVILFPFIGILLLSQISSYRISSWLNTLFSFLSFVGSLFLLFKKDPPGSFFLVDELNIVFILLTNFIGFTTALFSQRYIAHEIEIGHLSPPSLRFYHSMYQALLFGMNLALCSNNIGLMWVSIEMATLSTVLMVGIYRTTESLEASWKYFILGGVGIALALFGTFLFYISARPTIGEGLAAMAWTNLFSHAAYLDSSLVNIGFIFILIGYGTKVGLFPLHGWLPDAHAEGPTPISAVLSGLLLNVALYAILRFKILLSANPHALQAGPLLTAMGLASVLFAALMFYKRRDIKRLFAYSSIEHMGIISFAFGIGGALANFAGLLHMSMHSLTKSAIFFAIGYISQIKRTQKIADLSGLTSSHPVLGWGLVFGVLAIAGLPPMGVFMSEFLVLSSAFARSPLLAACLAVGLITALGALILKLVQVSFGEPRGDSSPIRSLYLPMFSHFLLVFAAGVYIPPRVVEWFQHCSVLLK
What are the official names of this protein?
Hydrogenase-4 component F homolog.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRI56_HUMAN
Sequence: MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity by mediating ubiquitination of CGAS and STING1 (PubMed:21289118, PubMed:29426904).  In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets STING1 to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta (By similarity).  Also mediate monoubiquitination of CGAS, thereby promoting CGAS oligomerization and subsequent activation (PubMed:29426904).  Promotes also TNFalpha-induced NF-kappa-B signaling by mediating 'Lys-63'-linked ubiquitination TAK1, leading to enhanced interaction between TAK1 and CHUK/IKKalpha (PubMed:35952808).  Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling.  Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES (PubMed:22948160).  Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus (PubMed:22948160).  Acts as restriction factor of Zika virus through direct interaction with the viral RNA via its C-terminal region (PubMed:31251739).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM56, RING finger protein 109, Tripartite motif-containing protein 56.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_SALDC
Sequence: MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MURB_BURMA
Sequence: MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRGRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPLALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE2A_RAT
Sequence: MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAGLRQAAKDALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKIREAVISRKRLSCDGLGPSDLLGKPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQRVQALQQRRPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDVTRAPVNGCCSLEG
What is the function of this protein?
Regulates mitochondrial cAMP levels and respiration (By similarity).  Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of Dnm1l (PubMed:28463107).
What are the official names of this protein?
cGMP-dependent 3',5'-cyclic phosphodiesterase, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
What are the subcellular locations of this protein?
[Isoform PDE2A3]: Cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Isoform PDE2A1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane.
Protein: PLC_LISMO
Sequence: MYKNYLQRTLVLLLCFILYFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTNLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
What is the function of this protein?
Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.  Important factor in pathogenesis, PI-PLC activity is present only in virulent listeria species.  It may participate in the lysis of the phagolysosomal membrane.
What are the official names of this protein?
1-phosphatidylinositol phosphodiesterase, Phosphatidylinositol diacylglycerol-lyase, Phosphatidylinositol-specific phospholipase C, PI-PLC.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Secreted and, to a lesser extent, cytoplasmic.
Protein: PHAA_THEVB
Sequence: MSVVTKSIVNADAEARYLSPGELDRIKNFVSTGERRLRIAQTLTENRERIVKQAGDQLFQKRPDVVSPGGNAYGEEMTATCLRDLDYYLRLVTYGIVAGDVTPIEEIGLVGVREMYNSLGTPIPAVAEGIRAMKNVACSLLSAEDAAEAGSYFDFVIGAMQ
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: TRI48_HUMAN
Sequence: MSRRIIVGTLQRTQRNMNSGISQVFQRELTCPICMNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECIKTIQQRNLKTNIRLKKMASLARKASLWLFLSSEEQMCGIHRETKKMFCEVDRSLLCLLCSSSQEHRYHRHCPAEWAAEEHWEKLLKKMQSLWEKACENQRNLNVETTRISHWKAFGDILYRSESVLLHMPQPLNLALRAGPITGLRDRLNQF
What is the function of this protein?
E3 ubiquitin-protein ligase which promotes K48-linked polyubiquitination of protein methyltransferase PRMT1, leading to PRMT1 degradation (PubMed:29186683).  This suppresses methylation of the PRMT1 substrate MAP3K5/ASK1, promoting its activation and increasing MAP3K5-dependent cell death induced by oxidative stress (PubMed:29186683).  TRIM48-mediated ubiquitination of PRMT1 also suppresses methylation of FOXO1 by PRMT1, leading to inhibition of FOXO1 transcriptional activity (PubMed:29186683).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM48, RING finger protein 101, Tripartite motif-containing protein 48.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PITM2_MOUSE
Sequence: MIIKEYRIPLPMTVDEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENNNVFNLSPVEKSQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTCRGPLSENWIQEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEREVQLMLSRKMAQFSEEGPSELSKDSATKDQASGTTSDPGSKNGEPLGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEGSEEEFFDAHENLYCTEEKQAKDMTKWNSNDLMDKMESPEPEESQDEIYQQSGSEFRVASSVEQLNIIEDEVSQPLAAPPSKIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFALVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGTLANAAHCSGGSGGGGSGGSSLESSRHLSRSNIDIPRSNGTEDSRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHSLPPFSIPRYQRYPLGDGCSTLLADVLQTHNTVFQEHAAPSSPGTAPAGRGFRRASEISIASQVSGMAESYTASSIAQKGPSSLNHTPSIRRLSLLALPPPSPTTQGPRARARQVSPNLERAPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPRERWQRKRTHVKLRNVAANHRINDAVANEDGPQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLHLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPRGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVAVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQSDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMAGRLEPGAATGPK
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro).  Binds calcium ions (By similarity).
What are the official names of this protein?
Membrane-associated phosphatidylinositol transfer protein 2, Drosophila retinal degeneration B homolog 2, RdgB2, Phosphatidylinositol transfer protein, membrane-associated 2, PITPnm 2, Pyk2 N-terminal domain-interacting receptor 3, NIR-3.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=May associate with the cytoskeleton.
Protein: PEP12_YEAST
Sequence: MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL
What is the function of this protein?
Plays a role in the sorting and targeting of vacuolar proteases.
What are the official names of this protein?
Syntaxin PEP12, Carboxypeptidase Y-deficient protein 12, Vacuolar protein sorting-associated protein 6, Vacuolar protein-targeting protein 13.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: Y808_ENCCU
Sequence: MGIIDVQRSHLTATPSKERDAPAHPPPTILPVCILFPYTSIALPVLMYYIPEKGQFDQNPFLKLIAILPPCLYSAVQFPLLFLGNPESSCTPRPALYATLYLLLDASLLAFSAISILSIAAFTTTEWNSDEVVAVCSTLLPSLLVLPAHLLSTSCALTPGSIGFTDSSVDILIDLLMVSLLAAGLTLNVDESWRFFPYICISSLVLVLAKLLRKSSSMPRRDPAPAPAWRIAAFVLIFGLSMFVYFSILHECLLIFGNHFPWFPSQAPSNDLTNKW
What are the official names of this protein?
UPF0328 protein ECU08_2080.
What is the protein family that this protein belongs to?
Belongs to the UPF0328 family.
Protein: ATG8E_ARATH
Sequence: MNKGSIFKMDNDFEKRKAEAGRIREKYPDRIPVIVEKAEKSEVPNIDKKKYLVPSDLTVGQFVYVIRKRIKLSAEKAIFIFVDNVLPPTGELMSSVYEDKKDEDGFLYITYSGENTFGASSI
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8e, Autophagy-related ubiquitin-like modifier ATG8e, AtAPG8e, Protein autophagy 8e.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: CYB_DRONO
Sequence: MAPNIRKSHPLLKIINNSLIDLPSPSNISAWWNFGSLLGICLITQILTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGITIIHLTFLHESGSNNPLGIVSHCDKIPFHPYFSLKDILGFTLMFIPLLILAFFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPFLHKSKQRSMTFRPLSQMLFWLLVANLLILTWIGSQPVEHPFIIIGQTASFTYFLILLILFPTIGALENKMLY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFP_ALKEH
Sequence: MAQYSTNEFKGGLKIMLDGDPYTIVENEFVKPGKGQAFNRVKVRNLKTGKVIDRTFKSGESVEAADVLETEMQFLYSDGEFFHMMDPETFEQKAAPASAVGDAAKWLKEQAMCTVILWNDEPLTVEPPNFVELRVVETDPGVRGDTSGGGGKPATLETGAVVRVPLFIEEGELLKVDTRSGEYVGRVKG
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL122_ORYSJ
Sequence: MASSNFFLLTALIALVATQAMASDPSPLQDFCVADRNSPVHVNGFPCKDAKDVNVDDFFLAANLDKPMDTTKSKAGSNVTLINVMKLAGLNTLGISMARIDYAPKGQNPPHTHPRATEILTVLEGTLYVGFVTSNQANGENKLFTKTLNKGDVFVFPQGLIHFQFNPSYDKPAVAIAALSSQNPGAITIANAVFGSNSPISDDVLAKAFQVDKKAVDWLQAQFWENNHN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 12-2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RPC8_BOVIN
Sequence: MFVLVEMVDTVRIPPWQFERKLNDSIDEELNKKLANKVMYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDIGEEVRFRVVDESFVDTSPTGPSSAEAASSSEELPKKEAPYTLMGSISEPGLGLLSWWTSS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA.  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC8, RNA polymerase III subunit C8, DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide, DNA-directed RNA polymerase III subunit H.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOD_STRZT
Sequence: MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRNMFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRELVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: EFG1_BORAP
Sequence: MDYNKLRNIGISAHIDSGKTTLTERILFYCNKIHAIHEVKGKDGVGATMDSMELERERGITIASAATHVEWKDFPINIIDTPGHVDFTIEVERSLRVLDGAILVLDSVAGVQSQSITVDRQLKRYSVPRLAFVNKCDKTGANPYNVKDQLRSKLDLNSVLMQIPIGLEDKHIGVIDLVLMKAYYFEGKDGTEIIEKEIPSELLEEAKNKREMMLDALADFNDELMELHMEGKEVPIEIIYNAIRTGTLALKLCPVFMGSAYKNKGVQLLLDAVTRFLPSPHDIKNTALDLNNNEKEIDLKIDNNLPTVALAFKLEDGQYGQLTYVRIYQGTLKKGQELINSRTSKKFKVGRLIRMHANNTEDIEFGGSGDIVALFGIECASGDTFCDPSINYSMTSMFIPDPVISLSVKPKDKKSADNMAKALGRFTKEDPTFKTYVDIESNETIIQGMGELHLGVYIERMKREFKAEVETGMPQVAYRETITGKAEFNYTHKKQSGGAGQFGRVAGFMEPLNKEGETYEFVNLIKGGVIPTEYIPSCDKGFQKAMEKGTLIGFPIVDIKITINDGQYHIVDSSDIAFQLAAIGAFREAYEKAKPTILEPIMKVTLEGPTEFQGNMFGLLNQRRGIITGSLEDGSFSKVEAEVPLSEMFGFSTVLRSSTQGKAEFSMEFLKYGKVPSAIFDELRKKFNDQNKS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YARQ_ENTAG
Sequence: MQLHELMDPDYSDNPFPLYRKLHQQGPLIPAGDKIIISGSHAVVDALLNDRRVGKNYMESVRVRFGDDAAGLPLFQGISRMFLVLNPPDHNRL
What are the official names of this protein?
Uncharacterized protein in aroQ 3'region.
Protein: RRF_STRGC
Sequence: MANAIVEKAKERMSHSHQNLAREFGAVRAGRANASLLDRISVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERAINASDLGITPASDGSVIRLVIPALTEETRRDLAKEVKKIGENAKIAIRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDEMTAHKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_CAUVN
Sequence: MKALSIPDVLAEVAVLVRPHFGKGKPADYIPQLATVPGGKFGMAVRMVDGDEHVIGDADEGFSVQSITKVFALGLALNRLGDEIWTRVGKEPSGTPFNHLSLLEAEQGVPRNPFINAGALAVTDVLMDVTRDPAALVRDFGGFLCGERLEIDPAVATSELAHAWQNRAIASLMRAKGTITHDPEAVVAAYCRQCALSMSCRQLARAFLPLAAGGFSPIAQETVFPERLTRRLNALLLTCGIYDSVGSFAYRVGLPAKSGVGGGIVAVVPGKATVAVWSPELDRFGTSVVGTAALEAFSQITNCSVL
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.