PharMolix/UniProtQA huggingface dataset:
Protein: AROA_VESOH
Sequence: MSKFIINPSNSMYGNLKIPGDKSISHRSIMLGSLANGVTKISGFLEGKDVLSTLKGFQNMGVKIERNSDNVIIYGVGLNGLKKSLVPLNFGNSGTSIRLISGILAAQTFDSELYGDESLSKRPMGRVINPLVQMGALIESNDGKLPIKIKGGQTLKGINYDLPVASAQVKSCILLAGLYAQGETCIKESILTRDHTERMLKGLGYRLDTNKNKICLTGGAQLNAANIQVPSDISSAAFFIVAASIAPQADITLIGVNVNPTRTGIIDILKLMGANLSLSNECVIGGELLANIRIQSAQLKGIRIPKDLVPLAIDEFPAIFIAASCAKGETILTNAKELRVKESDRIQVMADGLSILGIENEVFEDGIKIKGGVFSKPSSTIKSHHDHRISMSFAIASLRCHYAIEIEDVDNVQTSFPNFVELANQIGMNISLVSA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX1_MACFA
Sequence: MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKRTTSLLPINNGSKENGIHEEQDQEPQDLFADATVELSLDNTQNNQKKVPAKTLISLPPQEAPNSSKHQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVMRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS
What is the function of this protein?
Involved in several stages of intracellular trafficking.  Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex.  The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC).  Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity.  Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1).  Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi.  Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R.  Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN.  Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (By similarity).
What are the official names of this protein?
Sorting nexin-1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans- Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Note=Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transport carriers (ETCs) which are budding from early endosome vacuoles just before maturing into late endosome vacuoles. Colocalized with F-actin at the leading edge of lamellipodia in a KALRN-dependent manner.
Protein: 708G2_CITUN
Sequence: MSDSGGFDSHPHVALIPSAGMGHLTPFLRLAASLVQHHCRVTLITTYPTVSLAETQHVSHFLSAYPQVTEKRFHLLPFDPNSANATDPFLLRWEAIRRSAHLLAPLLSPPLSALITDVTLISAVLPVTINLHLPNYVLFTASAKMFSLTASFPAIVASKSTSSGSVEFDDDFIEIPGLPPIPLSSVPPAVMDSKSLFATSFLENGNSFVKSNGVLINSFDALEADTLVALNGRRVVAGLPPVYAVGPLLPCEFEKRDDPSTSLILKWLDDQPEGSVVYVSFGSRLALSMEQTKELGDGLLSSGCRFLWVVKGKIVDKEDEESLKNVLGHELTEKIKDQGLVVKNWVDQDKVLSHRAVGGFVSHGGWNSLVEAARHGVPLLVWPHFGDQKINAEAVERAGLGMWVRSWGWGTELRAKGDEIGLKIKDLMANDFLREQAKRIEEEARKAIGVGGSSERTFKELIDKWKCNNNTH
What is the function of this protein?
UDP-glucose-dependent glucosyltransferase catalyzing the C-glucosylation of 2-hydroxyflavanones (2-hydroxylnaringenin and 2-hydroxypinocembrin) and phloretin (PubMed:28370711).  No activity with flavanones, flavones or flavonols (PubMed:28370711).  Exhibits C-glucosylation activity toward 2-phenyl-2',4',6'-trihydroxyacetophenone (PubMed:28370711).  Can use UDP-xylose as sugar donor, but catalytic efficiency is much lower toward UDP-xylose than toward UDP-glucose (PubMed:28370711).
What are the official names of this protein?
UDP-glycosyltransferase 708G2, 2-hydroxyflavanone C-glucosyltransferase, CuCGT.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RK22_ORYSJ
Sequence: MTSFKLVKYTPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKVQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKANLFITKAEVSRSTIMNKFRPRARGRSSPIKKTMCHITIVLNIVKKSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GREA_STAEQ
Sequence: MENQKQYPMTQEGYEKLEQELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMIRNALIIEDNGDNNVVQIGKTVTFIELPGDEEESYQIVGSAEADAFKGKISNESPMAKALIGKGLNDQVRVPLPNGGEMNVKIVEIK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TIG_MYCSS
Sequence: MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGREAMLDQVVGEAVPGRYTEAVTSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPDLSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAKDGDFVSIDLSATVDGKDVPEATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKERELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPEKIVQAQIDDTVHNAIHGLDHDEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDALADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQLPAMFADVRRGLTIAAVVHGATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FMT_AQUAE
Sequence: MKRILFMGTPQFAVPSLEEFAKNFKVIGVVAQPDKPAGRGKKLTPPPTKVLAQKLGIPIYQPEKKKELIPLVEELKPDCIVVVAYGKILPKEVLDLPPYKTINLHASLLPKYRGAAPIQRAIMAGEKETGNTVMLVNEEMDAGDILAQEKIPIEEEDNFLTLSEKLAKSGAKLLVNTLRLWFEGKVKPVPQNHEEATYAPPVQKEEYRICWKASAESVRDRIRGLYPNAYTTFRGNRIKILKARVVDLEGYPGEIQDTKRLIVACGEKSLEILELISPKGKKMRGEDFMRGYRPQLYEPFNSE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TGT_DESHD
Sequence: MAVRIEVLKEDNRTRARLGKLHTPHGVIETPVFMPVGTQATVKTMTPEELKDLGAGIILSNTYHLFLRPGHELIREAGGLHAFMHWDGAILTDSGGFQVFSLGDLRKITEEGVEFRSHLDGSKKFLSPEIATQVQMALGSDIVMAFDECTPYPATRDYAKASLERTTRWLKRCQETLTTTDRQALFGIVQGSMYEDLRKQSAAEITELDLPGYAVGGLSVGEPKELMYEVLDYTVPLLPKDKPRYLMGVGSPDALIEGVMRGIDMFDCVLPTRIARNGTALTRYGKLVVRNAESAHDFSPIDPTCDCYTCKNYSRAYLRHLIKADEILGLRLMTIHNLRFLTNLMSEIRAAIKENRLPEYREKFFYEYGYLK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ATPF2_MICAN
Sequence: MFDFDATLPVMALQFILLAVILNAVFYKPLSKVLDERAEYIRQTESGAKEQLAKTEALVQEYELQLSSARKQSQEIIAQAQAEAQKLASERVAAAQKEAIARKEAVAAEIAQQKEEAFRSLEGQVASLSRQILEKLLGPELVR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RL30_MACCJ
Sequence: MAKIQITLTRSIIGRPETQRKTVKALGLTKMHSSVEVEDNPAIRGQINKVSHLVTVKEL
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ATPF_ACIAD
Sequence: MNINLTLIGQAIAFAIFVAFCMKFVWPPLINAISERQRKIADGLNAAEKAKADLADAQAQVKQELDAAKAQAAQLIEQANRRAAQLIEEARTQATAEGERIRQQSKETVDQEINAAREELRQQVAALAVDGAEKILNQQVDQQAHAAMLEQLAAKL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPOB_CLOBM
Sequence: MVHPVQVGKRTRMSFSRLKEVGQMPNLIEVQLDSYDWFLKEGLQEVFDDINPIQDYTGNLNLEFVGYKLDLDSIKYSVEECKERDSTYAAPLKVKVRLLNKETGEIKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDMTVDKTGSKLFSATVIPNRGAWLEYETDSNNIIYVRIDKTRKLPITILARALGYGTDAEIIEFFGEDERLKATIEKDNTKTREEALLEIYKRLRPGEPPTVDSAESLIESLFFDAKRYDLSRVGRYKFNKKLAIHLRITNQIADQDIVNPQTGEILVQKGEKIDKDKAIEIQNCGVNEVYIKIDDKSFKVIGNHFVDIHSLISFDISDLNIKEYVFYPVLKEILDNYADEESIKEEIRKNIYRLIPKHIIREDIYATINYELGLSYDIGYKDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATFAKVNEYGFIETPYRRIDPKNKRATNDIVYMTADEEDLYVIARSDEPIDENGYFMDDKVTVRAKEEVLVVPVSEVEYMDISPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAATDSGVLPKAKNAGTVAYVSADEIRVRRDSDGGIDKYKLLKFKRSNQGTCINQRPIVSKGEVVAKETLLADGPSTDLGEIALGKNILMGFITWEGYNYEDAMLISEQLVREDVFTSIHIEEYEAEARDTKLGPEEITRDIPNVGEEALKDIDERGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDVKIFTRENGDELPPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGLAASKLGWHIATPVFDGAIESDIVDCLRKAGYSEDGKTVLYDGRTGEPFDNRVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDVKVLNDDNQEIKLKESVDEDVDELEVNIEGAENQLEDKEEKEEEKEENYKEDSDEYDDLREEDVEPDLEELSLDDLDLDDFGDEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: APCE_NOSS1
Sequence: MSVKASGGSSVARPQLYQTLAVATITQAEQQDRFLGRGELDELASYFASGAKRLEIAQLLTENSEIIVSRAANRIFVGGSPMAFLEKPREPELAMAAVGGGGDVRESMKLGTVTYVETRGGFLENLRSIFNTSPSGPTPPGFRPINIARYGPSNMAKSLRDLSWFLRYATYAIVAGDPNIIVVNTRGLREIIENACSGEATIVALQEIKAASLSYFRKDPEAAEIVSQYMDVLITEFKAPTPSNKLRQRPSGDQQGLQLPQIYFSAAERRPKFVMKTGLSATEKNEVIKAAYRQIFERDITRAYSLSISDLESKVKNGDISMKEFVRRLAKSPLYQKQFYQPFINSRVIELAFRHILGRGPSSREEVQKYFSIISNGGLPALVDALVDSAEYSDYFGEETVPYLRGLGQEAQECRNWGPQQDLFNYSAPFRKVPQFITTFAAYDRPLPDQHPYGSGNDPLEIQFGAIFPKETRNPSTSPAPFGKDTRRILIHQGPGINNQVSNPSARGLAPGSLGPKVFKLDQLPGTIGKKAAKGASVKFSESSTQAVIKATYLQVFGRDVYEGQRLKVQEIKLENGEISVRDFVRALAKSDLFRKLYWTPFYVCKAIEYIHRRLLGRPTYGRQENNKYFDIASKKGLYAVVDAILDSLEYTETFGEDTVPYERYLTPAGVALRQLRVGTIREDVANVEKQETPRFVELGTVKENRTQPDIDFRINQGVTKQREQTKVFKRVAGIKDKAAIKTLISAAYRQIFERDIAPYIAQNEFSGWESKLGNGEITVKEFIEGLGYSNLYLKEFYTPYPNTKVIELGTKHFLGRAPIDQAEIRKYNQILATQGIRAFINALVNSQEYNEVFGEDTVPYRRFPTLPAANFPNTQKLYNQLTKQNNDVVIPSFKPVQARIQSDKTPILAKAIADLAAQAKQMDKSKPLFIELGRSYNDGRGQSVEVGVGTTRRKPARIYRLTNGIGQAEKQLVINAIYRQVLDVFSGQVPDYYRRTELDSKLRNGEISVREFVREIASSEIYRKRFYTPYPNTKVIEFLFRHLLGRAPATQGEIRQYNKLLADNGLRAAVEAIVDSPEYSRYFGEDVVPYPRFPSLPAGNYLGSVQAAADLVKQSWSSLSPSTLTGRPGDR
What is the function of this protein?
This protein is postulated to act both as terminal energy acceptor (by its phycobilin-like domains) and as a linker polypeptide (by its repeats and arms) that stabilizes the phycobilisome core architecture.  Has intrinsic bilin lyase activity (By similarity).
What are the official names of this protein?
Phycobiliprotein ApcE, Anchor polypeptide, PBS-anchor protein, Phycobilisome linker polypeptide.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Anchors the phycobilisome perpendicularly to the cytoplasmic surface of the thylakoid membrane.
Protein: DPM1_DICDI
Sequence: MSTKNRSDKSSSSSITKDKYTIILPTYKERENLPIIIWLISTELEKCFIDYEVVIVEDNSPDGTLEVAQQLQKIYGEEKIKILSRPGKMGLGSAYMDGIKKSTGNWVILMDADLSHHPKFIPQFIEKQKKLNCEIVTGTRYQSGGGVFGWNLYRKLTSRVANYIASVLLTPGVSDLTGSFRLYRKDVLEKLITQNKSKGYVFQVEMMVRANQLGYQVGEVPITFVDRIFGVSNLDSGEIVGFLKSVLNLFMNIE
What is the function of this protein?
Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.
What are the official names of this protein?
Dolichol-phosphate mannosyltransferase subunit 1, Dolichol-phosphate mannose synthase subunit 1, DPM synthase subunit 1, Dolichyl-phosphate beta-D-mannosyltransferase subunit 1, Mannose-P-dolichol synthase subunit 1, MPD synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: THTR_MYCS2
Sequence: MARSDVLVSTDWAESNLKAPKTVFVEVDEDTSAYDTGHIEGAVKLDWKTDLQDPIRRDFVDAQQFSKLLSERGIANDDTVILYGGNNNWFAAYAYWYFKLYGHQDVKLLDGGRKKWELDARPLSAEKVERPQTSYTAKEPDNSIRAFRDEVIAAIGTKNLVDVRSPDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSKAANEDGTFKSDEELAKLYAEAGLDGEKETIAYCRIGERSSHTWFVLQELLGHKNVKNYDGSWTEYGSLVGAPIELGS
What is the function of this protein?
May be a sulfotransferase involved in the formation of thiosulfate.
What are the official names of this protein?
Putative thiosulfate sulfurtransferase, Rhodanese-like protein.
Protein: Y482_BUCAI
Sequence: MFTKGGLGNLMKQAQQMQEKMAKIQEEIAQMEVTGEAGAGLVKVTINGAHNCRRVEVDPSLLQDDKDMLEDLAAAAFNDATRRISEVQKKKMSAISTGMQLPNGFNMPV
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BU482.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FIBA2_PETMA
Sequence: MTLRGVSMVLTWCLLVSKAWSSGDDSSIDIRGPRLVMPSQARDSCSTQQTTELCVEGNWGRKCPGGCRMLSMLSRTEKDSMRRVDELTKRLARMIQLHTEIHSYYRSVSDVSNQVVTDREDTEARFYALLSDLERKIIYLQRRINGQLTLLSQLRNGIAQQTSTILQLEVDTDVALRTCKGACARQVRYRVDKEMNLQLEKANAYLSGINLALFEEIVHESFSVERDDARSLHPYSGGPASDSEPRDGDGTASQATGFRSDATDPGVSHGNSSKSFGNVDERSKVEKDVNVASTSSVSSSSSSSSSSSSTSSTISSTQKTEELSFKKVSVSTAAVAGKDTDDFQWDSVQTASQTEEGFVRDTGADSTWNQHNVQWNSDFGTASDDEPDFQARSHRTNLSEYIDCLDVLQRRPGGKASGLYEVRPRGAKRALTVHCEQDTDGGGWTLVQQREDGSLNFNRSFSAYREGFGTVDGSGHGELWLGLEAMYLLAHEDSTMRVELQGWDGAGAHAEYTVTLRDDSKGYALQVSDYRGTAGNALVSGVADDPELTSHGGMTFSTYDRDTDKWSDGSCAEWYGGGWWINACQAANLNGVYYQGGPYDPREKPPYEVENGVVWATYRGSDYSLKRTAVRFRRVQIPIVE
What is the function of this protein?
Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
What are the official names of this protein?
Fibrinogen alpha-2 chain.
What are the subcellular locations of this protein?
Secreted.
Protein: Y017_HIS1I
Sequence: MIDSLTTLMIYFFLPVSYLLVGFVIMYYTREAFKKHMLENMVSPMWQNYVFVMILLIWPFFLFLVVTTTILKLFKAVVN
What are the official names of this protein?
Putative transmembrane protein ORF17.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: SUMT_PSEAE
Sequence: MSGKVWLVGAGPGDPELLTLKAVRALQDADVVMVDDLVNPSILEHCPSARLVRVGKRGGCRSTPQDFIQRLMLRHARQGRSVVRLKGGDPCIFGRAGEEAEWLARHGIDSEIVNGITAGLAGATACGIPLTYRGISRGVTLVTAHTQDDSPLAWEALARSGTTLVVYMGVARLAEIQAGLLAGGMAEDTPLAMIENATLGNQRECRSNLGELLRDAGRFALKSPAILVIGEVTRDIVSQPISLSA
What is the function of this protein?
Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1.  It is a step in the biosynthesis of both cobalamin (vitamin B12) and siroheme.
What are the official names of this protein?
Uroporphyrinogen-III C-methyltransferase, Urogen III methylase, S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT, Uroporphyrinogen III methylase, UROM.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: ASL1_SCHPO
Sequence: MRTTFATVALAFLSTVGALPYAPNHRHHRRDDDGVLTVYETILETVYVTAVPGANSSSSYTSYSTGLASVTESSDDGASTALPTTSTESVVVTTSAPAASSSATSYPATFVSTPLYTMDNVTAPVWSNTSVPVSTPETSATSSSEFFTSYPATSSESSSSYPASSTEVASSYSASSTEVTSSYPASSEVATSTSSYVAPVSSSVASSSEISAGSATSYVPTSSSSIALSSVVASASVSAANKGVSTPAVSSAAASSSAVVSSVVSSATSVAASSTISSATSSSASASPTSSSVSGKRGLAWIPGTDLGYSDNFVNKGINWYYNWGSYSSGLSSSFEYVLNQHDANSLSSASSVFTGGATVIGFNEPDLSAAGNPIDAATAASYYLQYLTPLRESGAIGYLGSPAISNVGEDWLSEFMSACSDCKIDFIACHWYGIDFSNLQDYINSLANYGLPIWLTEFACTNWDDSNLPSLDEVKTLMTSALGFLDGHGSVERYSWFAPATELGAGVGNNNALISSSGGLSEVGEIYIS
What are the official names of this protein?
Alkali-sensitive linkage protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Secreted, cell wall. Note=Covalently attached to the cell wall.
Protein: PYRB_WIGBR
Sequence: MTNFIYNKHIISINDLSKKEMNSIIDFSFSFKLKSFNTFLKNKIIAICFLEASTRTRLSFESAIYRSGGTCIGFSDSSNTSLEKKGESFIDTISIISKYVDAIIVRHPKEGAARLASEYSNNIPVINAGDGANQHPTQTILDLFSIKETQGKLDNLNIAIIGDLKYSRTVHSLSQAISKFKKNKIYFIAHSALMLPSYIINILEEKKVEYSFHDSIEEVIKKIDILYITRIQKERLDSSEYANINAKFILKKSDLFYAKKNLKILHPLPRSNELSFEVDKTSYAYYFQQAENGLFVRQAILSSILNKKL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UL109_HCMVA
Sequence: MIHDYHWRRGKRRKLIVMMETRMMIIMMTIKPPHDIYREQQNHHDDETKRSTKHCVTATHPWPRPAASCFRCPLRGGHHRRRPACALPHGWSVMNSCS
What are the official names of this protein?
Uncharacterized protein UL109.
Protein: SYI_PSEA6
Sequence: MSDYKHTLNLPETEFPMRGNLAQREPKMLQDWTNKALYHKIRAAKKGKTPFILHDGPPYANGDIHIGHAVNKILKDVIVKSKTLSDFDSPYVPGWDCHGLPIELMVEKKVGKPGKKVTAAEFRQKCRDYAEKQINGQKADFIRLGVLGEWDKPYRTMDFSSEANIIRELGNVVRSGHLEKGFKPVHWCTDCGSALAEAEVEYQDKVSPSIDVRFNIADEASFTKQFTAIGEGLGEGTISVVIWTTTPWTLPANRAVSLHPELEYSLVQVQSENGNERLVVATDLLDECVKRFGFENTHVLGTALGQALENMQVQHPFYDFTVPLILGEHVTTDSGTGCVHTAPGHGVEDFNVGRQYNLEVANPVGANGVYLENTPIFAGEHVFKANEHVVEVLAERGALVHHVKYTHSYPHCWRHKTPLIFRATPQWFISMDKNGLRAASIKEIHKTQWIPEWGESRIESMVAGRPDWCISRQRTWGVPIALFVHKDTGDLHPNTDALIEQVAQRVESEGIQAWWDIDPQEMLGDDADTFVKVLDTLDVWFDSGVSHYFVVDKRDDIPASADLYLEGSDQHRGWFMSSLMTSVATKGHAPYKQVLTHGFTVDGKGKKMSKSLGNTVAPQQVTNKLGADILRLWVASTDYRSEIAVSDEILKRSADAYRRIRNTSRFLLANLTGFNPKTDLVPFEEMVELDKWAVSRAHTMQREIVKAYEAYDLLVVTQKLMQFCSIEMGSFYLDIIKDRQYTAKSDSHARRSCQSALYHIVEALVRWMAPITSFTAQEIWQEMPWQEDEFVFTGTWYTGLTAQADNTEFNDAFWQQVLAVKDEVNRTIELARKEGTIGGSLEAEVKIYATAELAELLSKLQDEARFVFITSSATVEAVESKPADATETEVPGLWLHISASEGKKCARCWHHREDVGTNESHPELCQRCVTNVDGEGETRAYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_NITHX
Sequence: MSKLKVTNARRKQRVRLSLRRTANGRPRLSVFRSSKHIYAQVIDDLKGETLASASSLEKTMRDAGNTGANIDAAKAVGKLLAERAVKNGVKEVVFDRGSYLYHGRVKALADAARESGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.