PharMolix/UniProtQA huggingface dataset:
Protein: SIAT2_CHICK
Sequence: MKPNLKQWKQLMLFGIFAWGLLFLVIFIYFTDSNSAEPVPSSFSYIETKRLLPLQGKQRVIMGAIHDPSFSEAIDGNEVLLNEDLLDTFKSETGSIKKWTDLEDAFRSEDEFFPSQIGRKSKSAFYQVNDDYLFAAGQPMSHNSFQEIAKFISADEDNPKESILQNNWSRQRRMRRRSTKHRRSQMLDESDDWDGLYSTMSKSFLYKLWKGDVSSKMLNPRLQKAMKDYLSTNKHGVRFKGKRNSKLTGDQLFCELKERVDVKTIDGKEAPFSTLGWEKHVPQIPLGKLYTHGFGSCAVVMSAGAILNSSLGDEIDSHDAVLRFNSAPTRGYEKDVGNKTTMRIINSQILTNPNHHFVDSSLYKDVILVAWDPAPYSANLNWYKKPDYNLFTPYVQHRKKNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCNEVHVYEYIPSVRQTDLCHYHELYYDAACTLGAYHPLLYEKLLVQRMNKGLQDDLYRKGKVILPGFKSVKCPERNNFPPL
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: HUTI_BACC2
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGVVGIENDVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEE_AQUAE
Sequence: MLRNKVRKTDTLIALNEVYESIQGEGLLVGLPSVFIRLQGCNLRCPWCDQPEALSFSGRKVKLSSLINELKKFTAKHIVITGGEPFAHRELPFIVEFLLSEGYSVQIETNGTLWVEEMEKFAEGIHITCSPKGVAKYYVHPKILKYAKELKFVVDKEFSKEVLKKEEFERFLREGKVVLQPESNRKEMMEKALKIQKELLKECYTVRVIPQVHKCFDLK
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: ARLY_COREF
Sequence: MEKHGTNEGALWGGRFSGGPSEAMFALSVSTHFDWVLAPYDVLASKAHAKVLHSAGLLSDADLDTMLEGLDQLGRDVADGSFGPLPSDEDVHGAMERGLIDRVGPEVGGRLRAGRSRNDQVATLFRMWVRDAIRGIAVGVTELIDALTTQAAAHPDAIMPGKTHFQAAQPVLLAHQLQAHAQPLLRDLERIRDLDKRLAVSPYGSGALAGSSLQLNPEAIAAELGFDSAADNSIDATSSRDFASEAAFVLAQIAVDMSRLAEEIIAWCTPEFGYIVLADAWSTGSSIMPQKKNPDVAELTRGKTGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPIVDSVAQLNLLLPAMTGLVSTLTFNTDRMRELAPAGYTLATDLAEWMVREGVPFREAHEASGACVRIAEGRGVDLVDLTDEELAGVDPRLTPAVRDVLTIEGAVASRATRGGTAGDRVSEQRDRINQANADHLAWATTPVRS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O51G2_HUMAN
Sequence: MTLGSLGNSSSSVSATFLLSGIPGLERMHIWISIPLCFMYLVSIPGNCTILFIIKTERSLHEPMYLFLSMLALIDLGLSLCTLPTVLGIFWVGAREISHDACFAQLFFIHCFSFLESSVLLSMAFDRFVAICHPLHYVSILTNTVIGRIGLVSLGRSVALIFPLPFMLKRFPYCGSPVLSHSYCLHQEVMKLACADMKANSIYGMFVIVSTVGIDSLLILFSYALILRTVLSIASRAERFKALNTCVSHICAVLLFYTPMIGLSVIHRFGKQAPHLVQVVMGFMYLLFPPVMNPIVYSVKTKQIRDRVTHAFCY
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51G2, Olfactory receptor OR11-28.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HBG_ATEGE
Sequence: MSNFTAEDKAAITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGVKVLTSLGEAIKNLDDLKGTFGQLSELHCDKLHVDPENFRLLGNVLVTVLAILHGKEFTPEVQASWQKMVAGVASALASRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HFLD_SHIDS
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPOLL_MACFA
Sequence: MDPRGILKAFPKRKKIHADASSKVLAKIPRKEEGEEAEEWLSSLRAHVVRTGIGRARAELFEKQIVQHGGQLCPVQGPGVTHIVVDEGMDYERALRLLRLPRLPPGAQLVKSAWLSLCLQERRLVDVAGFSIFIPSKYLDQSQPSKAEQDASLPPGTHEALLQTALPPPPSPTRPVSPPQKTKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPASLEGDCDPSPAPVVLDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYNDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQQGFLTDDLVSQEENGQQQKYLGVCRLPGPGWRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNTHGCKMGPGRVLPTPTEKDVFRLLGLPYREPAERDW
What is the function of this protein?
DNA polymerase that functions in several pathways of DNA repair.  Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA.  Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination.  Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities.  Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
What are the official names of this protein?
DNA polymerase lambda, Pol Lambda.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APT_EXIS2
Sequence: MEFKQHIKEVENWPKEGISFKDITSLMQNGPAYKQSVDALIDYARKQGADVIAGPEARGFVVGCPAAYAMEIGFVPVRKEGKLPRETVRVEYGLEYGKDVLTMHHDAIQPGQRVVILDDLLATGGTIEATIKMIEQLGGTVAGIGFLIELDGLGGREKLEGYDILSLIRYAD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_SHESH
Sequence: MATVNQLVRKPRAPKVDKTNVPALDACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVSERRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TRMN6_HAES1
Sequence: MAKKQEFTFKQFHINQDQCAMKVGTDGILLGAWANINQANTLLDLGTGTGLIALMLAQRSPEHCHISAVELDPQAYLQAKDNIQQSPWANKIKIFQQDIIVFAQDCEHKFDVITANPPYFKQGIDCASKQRNLARYTLTQSHLDWLNAAEKLLNLTGEIHLILPFEEGKSLQKKCGLFCIRECKIITKAGKTPQRLLLSFSREERKCEESQLVIYDRNNQYSTEFKTLTQDFYLNF
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_CHLPD
Sequence: MAGFIGKERHALDEKGRLMIPVRFRRELSPESTGRGSTIYLMKAPDGSIELYEPDIWEGMKKSLAVLSDFNPEERLLKTMIYESLDVVAIDRQGRVPFSREFLEHAGIVRDVVIIGADTKMIVWAPERLSLLVMENAERYSSLARRYF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LOLA_YERPE
Sequence: MKRLLVACCFLSGLISASALADASTDLQNRLSKVNSFHASFSQAVTSSDGAVVQEGEGELWVKRPNLFNWHMTSPDESVLISDGETLWFYNPFVEQATATWLKNATGNTPFMLITRNNPDDWKQYNVKQKGDDFELTPKSASGNLKQFAISVTPSGTIKSFTAVEQDGQRSAYTLKSQQSSVVDASKFTFTPPKGVTLDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FRA1_ALIFS
Sequence: MTHPIIHDLENRYTSKKYDPSKKVSQEDLAVLLEALRLSASSINSQPWKFIVIESDAAKQRMHDSFANMHQFNQPHIKACSHVILFANKLSYTRDDYDVVLSKAVADKRITEEQKEAAFASFKFVELNCDENGEHKAWTKPQAYLALGNALHTLARLNIDSTTMEGIDPELLSEIFADELKGYECHVALAIGYHHPSEDYNASLPKSRKAFEDVITIL
What is the function of this protein?
Involved in bioluminescence.  It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction.  Major FMN reductase.  It is capable of using both NADH and NADPH as electron donors.  As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective.
What are the official names of this protein?
Major NAD(P)H-flavin oxidoreductase, FRASE I.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: GRCA_HAEI8
Sequence: MIKGIQITQAANDNLLNSFWLLDSEKNEVRCLCAKGEFAEDQVVAVSELGQIEYRELPVNVAPTVKVEGGQHLNVNVLRRETLEDAVNNPDKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: DDX3L_MOUSE
Sequence: MSHVAEEDELGLDQQLAGLDLTSRDSQSGGSTASKGRYIPPHLRNREAAKAFYDKDGSRWSKDKDAYSSFGSRSDTRAKSSFFSDRGGSGSRGRFDERGRSDYESVGSRGGRSGFGKFERGGNSRWCDKADEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALRAMKENGKYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEEADKRSFLLDLLNATGKDSLILVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGGSRGRSKSRFSGGFGARDYRQSSGASSSSFSSGRASNSRSGGGSHGSSRGFGGGSYGGFYNSDGYGGNYSSQGVDWWGN
What is the function of this protein?
Putative ATP-dependent RNA helicase.  Possible role in a key step of the spermatogenic process.
What are the official names of this protein?
Putative ATP-dependent RNA helicase Pl10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
Protein: SGAT_ARATH
Sequence: MDYMYGPGRHHLFVPGPVNIPEPVIRAMNRNNEDYRSPAIPALTKTLLEDVKKIFKTTSGTPFLFPTTGTGAWESALTNTLSPGDRIVSFLIGQFSLLWIDQQKRLNFNVDVVESDWGQGANLQVLASKLSQDENHTIKAICIVHNETATGVTNDISAVRTLLDHYKHPALLLVDGVSSICALDFRMDEWGVDVALTGSQKALSLPTGLGIVCASPKALEATKTSKSLKVFFDWNDYLKFYKLGTYWPYTPSIQLLYGLRAALDLIFEEGLENIIARHARLGKATRLAVEAWGLKNCTQKEEWISNTVTAVMVPPHIDGSEIVRRAWQRYNLSLGLGLNKVAGKVFRIGHLGNVNELQLLGCLAGVEMILKDVGYPVVMGSGVAAASTYLQHHIPLIPSRI
What is the function of this protein?
Photorespiratory enzyme that catalyzes transamination reactions with multiple substrates, including asparagine.  Functions exclusively as a catabolic enzyme in Asn metabolism (PubMed:18235971, PubMed:23098902).  Involved in root development during seedling establishment after seed germination by regulating serine homeostasis and acetate conversion (PubMed:31161264).
What are the official names of this protein?
Serine--glyoxylate aminotransferase, Alanine--glyoxylate aminotransferase, AGT, Asparagine aminotransferase, Serine--pyruvate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: YJBM_ECOLI
Sequence: MWVNKYIDDCTDEDLNDRDFIASVVDRAIFHFAINSICNPGDNKDAMPIEQCTFDVETKNDLPSTVQLFYEESKDNEPLANIHFQAIGSGFLTFVNACQEHDDNSLKLFASLLISLSYSSAYADLSETVYINENNESYLKAQFEKLSQRDMKKYLGEMKRLADGGEMNFDGYLDKMSHLVNEGTLDPDILSKMRDAAPQLISFAKSFDPTSKEEIKILTDTSKLIYDLFGVKSEK
What are the official names of this protein?
Uncharacterized protein YjbM.
Protein: ZAPA_ECOHS
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: KAD_STAAW
Sequence: MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETELGKEAKSYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIMSELDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGICDIDGGKLYQREDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKDISDVTKDVIDILDHL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_YERPN
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKATNGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PGLZ_ECOHS
Sequence: MQNQDFIAGLKAKFAEHRIVFWHDPDKRFIEELEQLKLENVTLINMTHASQLAVKKRIEMDEPEQQFLLWFPHDAPPHEQDWLLDIRLYSSEFHADFAAITLNTLGIPQLGLREHIQRRKAFFSTKRTQALKNLVTEQEDETSLDKKMIAVIAGAKTAKTEDILFNLITQYVNQQTEDDSELENTQAMLKRHGLDPVLWEMLNHEMGYQAEEPSLENLLLKLFCTDLSAQADRQQRAWLEKNVLLTPSGRASALAFMVTWRADRRYKEAYDYCAQQMQAALRPEDHYRLSSPYDLHECETTLSIEQTIIHALVTQLLEESTTLDREAFKKLLSERQSKYWCQTQPEYYAIYDALRQAERLLNLRNRHIDGFHYQDSATFWKAYCEELFRFDQAYRLFNEYALLVHSKGAMILKSLDDYIEALYSNWYLAELSRNWNEVLEAENRMQAWQIPGVPRQKNFFNEVVKPQFQNPQIKRVFVIISDALRYEVAEELGNQINTEKRFTAELRSQLGVLPSYTQLGMAALLPHEQLCYQPSNGDIVYADGLSTSGIPNRDTILKNYKGMAIKSKDLLELKNQEGRDLIRDYEVVYIWHNTIDATGDTASTEDKTFEACRTAVTELKDLVTKVINRLHGTRIFVTADHGFLFQQQALSVQDKTTLQIKPENTIKNHKRFIIGHQLPADDFCWKGKVADTAGVSDNSEFLIPKGIQRFHFSGGARFVHGGTMLQEVCVPVLQIKALQKTAAEKQPQRRPVDIVAYHPMIKLVNNIDKVSLLQTHPVGELYEPRILNIYIVDNANNVVSGKERISFDSDNSTMEKRVREVTLKLIGANFNRRNEYWLILEDAQTETGYQKYPVIIDLAFQDDFF
What is the function of this protein?
BREX systems (bacteriophage exclusion) provide immunity against bacteriophage.  Part of a type 1 BREX system which protects against dsDNA phage.  This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA.  Methylation of bacterial DNA by PglX guides self/non-self discrimination.  When the brxA-brxB-brxC-pglX-pglZ-brxL genes are transformed into a susceptible E. coli strain (BW25113) they confer very high resistance to infection by bacteriophage VR7 and VpaE1, about 100-fold protection against lambda, T5 and T7 and no protection against RNA phage Qbeta, ssDNA phage M13 or dSDNA phage T4 and VR5.  Glycosylated phage DNA is not susceptible to BREX.  The BREX system does not confer resistance to lysogenic lambda phage, i. e.  prophage that are integrated into the chromosomal DNA and then induced to form phage.
What are the official names of this protein?
Alkaline phosphatase-like protein BrxZ, BREX protein PglZ.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase superfamily.
Protein: YIHY_SHIFL
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLPLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DES1L_ARATH
Sequence: MGKGGREKISSNEEEREGVMATDFFWSYTDEPHASRRRQILSCYPQIRQLFGPDPWAFLKITLVVILQLSTAAILHNSGWLKILSIAYFFGSFLNHNLFLAIHELSHNLAFSTPVYNRCLGIFANLPIGVPMSVTFQKYHLEHHRFQGVDGIDMDVPTYTEAHLVTNIFAKTIWVFLQLFFYALRPIFIKPKPPGYWEFINFLIQIVLDVSVVLFFGWRSFAYLILSTFVGGGMHPMAGHFISEHYVFNPNQETYSYYGPLNLLTWSVGYHNEHHDFPRIPGNKLHLVKEIAGEYYEGLESYKSWSQVIYMYIMDTTVGPYSRMKRKLSKSD
What is the function of this protein?
Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives.  May be required for the biosynthesis of glucosylceramides.
What are the official names of this protein?
Sphingolipid delta(4)-desaturase DES1-like.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: VE6_HPV65
Sequence: MADGRPAALDDFCRRFDISFFDLHLTCIFCSHTVDLQDLASFYLKKLSLVFRGGCYYACCSECLRLSARFEQENYFQCSIKAVNLEEVAQRKIKEICIRCICCLRLLDIVEKLDLLYSDQACYLIRGLWRGYCRNCIRKQ
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MRUPP_HUMAN
Sequence: MRPVDADEAREPREEPGSPLSPAPRAGRENLASLERERARAHWRARRKLLEIQSLLDAIKSEVEAEERGARAPAPRPRAEAEERVARLCAEAERKAAEAARMGRRIVELHQRIAGCECC
What is the function of this protein?
May play a role in cell proliferation.
What are the official names of this protein?
Putative MORF4 family-associated protein 1-like protein UPP, Unnamed protein product, UPP.
What is the protein family that this protein belongs to?
Belongs to the MORF4 family-associated protein family.
Protein: HMUV_HYDCU
Sequence: MLTAEKLCVERQGHRILSDVSVEISPGQVVAVLGANGAGKSTLLQCLSGDVSEAKQHVFLNGKNLDSYTSQALAMARAVMPQSVQMDFAFLVSELVEMGLWQIPRQSDKQQRVDEALALFGIETLKQRDYQTLSGGEQQRVQLARVVAQLLTPIAQADAPRYLLLDECTANLDFAHQHQVFEVVKKLANTYQMGVVVVLHDMNLAAQYADHLVLLKQGKVLDQGSVESMLIPSKIEELYDFPVQVLPHPKGWPMIVPA
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MAM33_YEAST
Sequence: MFLRSVNRAVTRSILTTPKPAVVKSSWRVFTVANSKRCFTPAAIMRNQETQRVGDILQSELKIEKETLPESTSLDSFNDFLNKYKFSLVETPGKNEAEIVRRTESGETVHVFFDVAQIANLPYNNAMDENTEQNEDGINEDDFDALSDNFANVNVVISKESASEPAVSFELLMNLQEGSFYVDSATPYPSVDAALNQSAEAEITRELVYHGPPFSNLDEELQESLEAYLESRGVNEELASFISAYSEFKENNEYISWLEKMKKFFH
What is the function of this protein?
Not known.  Binds to the sorting sequence of cytochrome b2.
What are the official names of this protein?
Mitochondrial acidic protein MAM33.
What is the protein family that this protein belongs to?
Belongs to the MAM33 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SET_DICDI
Sequence: MSKHQKKEVEVEFEKDDPKAVYLELFDKDTELKSLSDEIEKLTGEKDLELMKCDKDIYKSAEPLYRERRALLLEIPDFWATIFTNLFLKLGFVDELTMCVDDFFVEDTETEFRLFIDFRENDIISNKQVIITVTTPTTSEELSQEVKISTTPIELKQNKTETEKKNKDSKKSTDDEDEDEDDDEISGFLKFLLNPTKDIATFIVGSVWSNPIDSFCNDDDEDYDGLIASDSEGEEDK
What are the official names of this protein?
Protein set homolog.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
Protein: DCUP_YERPP
Sequence: MNELKNDRYLRALLRQPVDMTPVWMMRQAGRYLPEYKATRAIAGDFMSLCKNAELACEVTMQPLRRYPLDAAILFSDILTIPDAMGLGLYFETGEGPRFQSPITCRADVEKLPIPDPEQELGYVMNAVRTIRRELAGSVPLIGFSGSPWTLATYMVEGGSSKAFTKLKKMMYAEPQTLHLLLDKLADSVILYLNAQIKAGAQSVMIFDTWGGVLTGRDYHEFSLNYMHKIVDGLIRENEGRRVPVTLFTKGGGPWLEAMAATGCDALGLDWTTDIADARRRVGDKVALQGNMDPSVLYAPPARIEQEVSTILASFGQGEGHVFNLGHGIHQDVPPAHAGAFVNAVHALSRPYHQK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2733_CLOBJ
Sequence: MHYCNKDIGSFGETIAVDYIKNCGYIILEKNFRCKLGEIDIIAKDKNFIVFIEVKTRYSYIYGSPSEAITFRKQNKIYKTAQLYIIKKAIHNKFYFRFDVIEVILNTLNSNYSVKLIKNAFQI
What are the official names of this protein?
UPF0102 protein CLM_2733.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.