PharMolix/UniProtQA huggingface dataset:
Protein: GLMM_STRPB
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIIFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CYB_LEIRU
Sequence: MALNLRKNHQILKIINDALIDLPAPSNISTWWNFGSLLGICLITQIITGLLLAMHYTADTNLAFSSVAHMCRDVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNVGVVLLLALMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIVGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTIKDILGFALMLSLLVSLALFAPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLTPLLHTSKLRSMTFRPLSQILFWTLVANVLILTWVGSQPVEHPFIIIGQLASFTYFTIILVLFPLAAALENKLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEM1_PARP8
Sequence: MQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKDIFLGRTARTAPEAAILSTCNRTELYCATDDHAAREAAIHWLSEYHNIAIDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQIVGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRTTTEIGAQSVSMAAAAVRLAQRIFDKVSNQRVLFIGAGEMIELCATHFAAQQPRELVVANRTAERGQRLAESYNGRAIPLSELPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLEDVFLYTVDDLGAIVREGNASRQAAVAQAETIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAEVDKAQKMLARGDDPAAVLEALSQALTNKLIHGPTHALNRASSENRDQLIELMGGFYKHAHPSSER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NCPP_YERE8
Sequence: MYHVVAATTNPAKIKAISLAFDDVYGPGQYRIEGINVDSGVPLQPIGSTETRTGARQRVSNARQMRPEADFWVGVEAGIEDNMTFAWMVIEHLQWRGESRSASLMLPDIILQGIRQGRELGDEMADLTGISNVKHKGGAIGIFTDGKLTRTSVYHQALLLALVPFNNEIYQRPAQ
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: RL31_SHELP
Sequence: MKPGIHPEYAEITATCTCGNVIKVNSTAGKPLHLDVCGACHPFYTGTQKVMDTGGRIDKFNKRFGMLGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SYGA_XANOM
Sequence: MSDSRRVPITFQGLIQTLNQYWAEQGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNIQDLYLGSLQALGIDPLVHDLRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEITYGLERLCMYLQRCDNVYALVWTYGPDGAAVTYGDVYHQNEVEQSTYNFEHANVAELFHRFDACEAEAKHLVEVGLPLPAYEQVSKASHAFNLLDARRAISVTERQRYILRVRALAQGVAQAYYAQREKLGFPGVKQ
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAC_HALMA
Sequence: MSSNPFNPFEAALNWQRKTLENMTDAAETSQVADERLELMESVDVGQTPSNVVYEENKLELLHYDAEAAGIEVPDEEKEDVPILIVYALINRPYILDLQEERSVVRRLLEAGHDVYLIDWNEPSRLDQHLTLDDYVNRYMDNCVDVVRDRSGQDAINILGYCMGGTMSVMYTALHKEKVNTLGLMAAGLCFDHTGGVLEEWGSEEYYSPQDVVDTFGNVPADMLDIGFALMDPVENYVTKYIRFAENMENEGFVENFGRMEQWLGDGIDVAGEAYVQFLEDVYQDNKLYKNELELDGKHVDLDNIDMPVLQLMGEYDHLIPPEASKPFNDVIASDDTRTIEFSTGHIGLSVSSSTHADLWPEVAEWYSERSTGSEEVDIEVESPEAAEDDAVDQSELTDIDVDATDDVDADATEDDATDEPADVDSVSGIGPTYAERLHDAGIHSVADLAEYDAADLADIAETTESRAQDWLDQL
What is the function of this protein?
Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation.  PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV).  Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaC, PHA polymerase, PHB synthase subunit PhaC, Poly(3-hydroxybutyrate) polymerase subunit PhaC, PHB polymerase, Polyhydroxyalkanoic acid synthase subunit PhaC, PHA synthase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family.
Protein: DNAB_MYCLE
Sequence: MAVVDDLAHSGMDAVPPSEDFGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRSGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYAGIVAEKALLRRLVEAGTRVVQYGYAGAEGADVAEVVDRAQAEIYDVAECRLSENYVPLEDLLQPTMDDLDAIASNGGISRGAPTGFTELDEVTNGLHPGQMIIVAARPGVGKALALDTPLPTPTGWTAMGDVAVGDELLAVDEAPTRVVAATEVMLGRPCYEIEFSDGTVIVADAQHQWPTSYGIRTSAQLRCGLDIIAAAGSTPRHAGRLTTAAFMAPVLCIDSVRRVRSVPVRCVEVDNAAHLYLAGRGMVPTHNSTLGLDFMRSCSIKHRLASVIFSLEMSKSEIVMRLLSAEAKIKLADMRSGRMTDDDWTRLARRMSEISEAPLYIDDSPNLTMMEIRAKARRLRQKTNLKLVVVDYLQLMTSGKRFESRQVEVSEFSRHLKLLAKELELPVVAISQLNRSPEQRTDKKPMLSDLRESGSLEQDADVVILLHRPDAFDRDDPRGGEADLILAKHRNGPTKTVTVAHQLHLSRFTNMAR
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: RECR_ALIF1
Sequence: MRTSGLLEQLMESLRCLPGVGPKSAQRMAFHLLQRNRQGGMQLADALSQAMSEIGHCSECRTFTEEDTCAICLNPKRQASGEMCIVESPADIVAVEATGQFSGRYFVLMGHLSPLDGIGPSDIGLDLLDHRLNRGDIKEVILATNPTVEGEATAHYIAELCQEHQVPASRIAHGVPMGGELELVDGTTLSHSILGRQKLY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TMN1_YEAST
Sequence: MIYKMAHVQLLLLYFFVSTVKAFYLPGVAPTTYRENDNIPLLVNHLTPSMNYQHKDEDGNNVSGDKENFLYSYDYYYNRFHFCQPEKVEKQPESLGSVIFGDRIYNSPFQLNMLQEKECESLCKTVIPGDDAKFINKLIKNGFFQNWLIDGLPAAREVYDGRTKTSFYGAGFNLGFVQVTQGTDIEATPKGAETTDKDVELETRNDRNMVKTYELPYFANHFDIMIEYHDRGEGNYRVVGVIVEPVSIKRSSPGTCETTGSPLMLDEGNDNEVYFTYSVKFNESATSWATRWDKYLHVYDPSIQWFSLINFSLVVVLLSSVVIHSLLRALKSDFARYNELNLDDDFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTCSIFFAALGFLSPSSRGSLATVMFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAILLIIIALNFFLMFVHSSGVIPASTLFFMVFLWFLFSIPLSFAGSLIARKRCHWDEHPTKTNQIARQIPFQPWYLKTIPATLIAGIFPFGSIAVELYFIYTSLWFNKIFYMFGFLFFSFLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIGGAGCALYVFIHSILFTKFKLGGFTTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSIKVD
What is the function of this protein?
With TMN2 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression.  Acts downstream of RAS2 and TOR.  Essential for cell adhesion and filamentous growth.  May play a role as effector of cellular copper homeostasis.
What are the official names of this protein?
Transmembrane 9 superfamily member 1, 70 kDa endomembrane protein, Endomembrane protein EMP70.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: MOS_PIG
Sequence: MPSPFPRRRCLPGDFSPSVDSRPCSSPCELPGPTGKLFLGGTPPRALRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYHGVPVAIKQVSRCTKNRLASQRSFWAELNIARLRHANIVRVVAASTRTPAAFDSLGSIIMEFGGNVTLHQVIYGATGCPEEDGPPCSAGEQLNLEKCLKYSLDVVSGLLFLHSQGIVHLDLKPANILISEQDVCKISDFGCSERLEDLRFRPRHHLGGTYTHRAPELLKGEPVTPKADIYSFAITLWQMTTRQVPYSGERQHVLYAVVAYNLRPSLSAAVFTESVPGKKLEDIIQCGWTAPAQQRPSAQLLLLDLRALQAELG
What are the official names of this protein?
Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: KDSA_LEPIN
Sequence: MKDNTCTKRDFLNGTKIGGDEPFFLISGPCVMENRDLLDRVCAEMIEVCGELKIPYIFKSSFDKANRSSVNSYRGPGLAEGIKNLEYIKNKYNVPVLTDIHETSQISPLKDVIDVYQIPAFLCRQTDLISQSAQTGKWVNVKKGQFLAPADTRHIAVKMNESGNNKLLVTERGTSFGYGNLIFDGRAIPIIHGFDIPLVFDATHSAQLPGAAGNSTGGQREFIPSILRSAVSFGIEGIFMEVHPDPPNALSDATTQYPLSQIKSLLKEMIGLDRYIKKEILISRSSL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VLN5_ORYSJ
Sequence: MSVSMKDLDPAFRGAGQKEGLEIWRIENFKPVPIPASSYGKFFMGDSYIILKTTALKNGSLRHDIHYWIGKDTSQDESGTAAILTVELDAALGGRAVQYREIQGNETDKFLSYFRPCIMPQPGGVASGFKHVEVNEQEHETRLYVCTGNRVVHVKEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYIKDTFHEGKCEVAAVEDGRLMADAEAGEFWGFFGGFAPLPRRAPVEDNEKYEETVFKLLCFNQGKLEPINYESLLHELLKTNKCYLLDCGVELFVWMGRTTSLQERKSASEAAEKLLSDDNRTKTHVIKVIEGFETVMFKSKFKEWPQTPDLKLSSEDGRGKVAALLKRQGLNVKGLMKAAPAKEEPQAYIDCTGSLQVWRINDKDKILLPSADQSKFYTGDCYIFQYMYPGDDKEECLIGSWFGKKSIEEDRVTAISLASKMVESAKFQAVQTRLYEGKEPIQFFVIFQSFQVFKGGLSSGYKKFIAENGIDDDTYLEDGLALFRIQGSGPENMQAIQVDAAASSLNSSYSYILHDGNTVFTWTGNLTTSLDQEVVERQLDIIKPNSQSRSQKEGSETDQFWSLLGGKSEYPSQKIGRANESDPHLFSCILPKGNLKIKEIYHFTQDDLMTEDVFILDCHSDIFVWVGQQVDVKVRLQALDIGEKFVKLDFLMENLSSDTPIFVIMEGSEPTFFTRFFTWDSAKSLMHGNSYQRKLSIVKGGGSPALDKPKRRTPTYSGRSTVQDKSQRSRSMSFSPERVRVRGRSPAFTALAANFESANSRNLSTPPPVVKKLYPKSATPDSSSAPSKSSATASLTGSFDRPKSVKDGSELEKPKQEEDAKEGINTMTSRVESLTINEDVKENEPEDDEGLPVYPYDRLITTAADPVTEIDVTRRETYLSSAEFKDKFGMTKEAFSKLPKWKQNRMKIALQLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein (By similarity).  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Villin-5.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL16_LACDA
Sequence: MPLVPKRVKHRREFRGKMRGAAKGGKTVAFGEYGLEALESHWITNRQIEAARVAMTRYMKRGGKVWIRIFPQKSYTAKGVGVRMGSGKGAPAGWVAVVKREKIMFEIGGVSEETAREAMRLAASKLPIKCKFVKREDQEAGGATNED
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ADPP_HAEIN
Sequence: MQFWRKQMSEIQHFSQQDIEILGEQTLYEGFFTLKRIQFKHKLFAGGQSGVVTRELLIKGAASAVIAYDPKEDSVILVEQVRIGAAYHPESHRSPWLLELIAGMVEKGEKPEDVALRESEEEAGIQVKNLTHCLSVWDSPGGIVERIHLFAGEVDSAQAKGIHGLAEENEDIKVHVVKREQAYQWMCEGKIDNGIAVIGLQWLQLNYAQLQQSWKRS
What is the function of this protein?
Acts on ADP-mannose and ADP-glucose as well as ADP-ribose.  Prevents glycogen biosynthesis.  The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity).
What are the official names of this protein?
ADP-ribose pyrophosphatase, ADP-ribose diphosphatase, ADP-ribose phosphohydrolase, ASPPase, Adenosine diphosphoribose pyrophosphatase, ADPR-PPase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudF subfamily.
Protein: RUVA_PELPB
Sequence: MFAYFRGKLTSVLPEEVVVEVSGIAYQFLISAATHRQLPEQGSEVFLFSHLVVREDLLQLYGFSGEEERQLFRLLLLTTGVGPKLALALLSGLSVQDIHDAILTNTPERLYGITGVGKKTAARIILELRDKVLKLSPVSALASPARLSSTLLRDDAVNALVTLGFSRIIVQKAVVAILEQNPGLTVEEVIKAALVSIHNS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AMN_ECO57
Sequence: MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDENARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLTLLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETADGIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGCSQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLVNIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAVLPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASALRFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAISEHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate.  Involved in regulation of AMP concentrations.
What are the official names of this protein?
AMP nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the AMP nucleosidase family.
Protein: PA2H_BOTSC
Sequence: MRTLWIVAVLLVGVEGSMYELGKMILLETGKNAATSYIAYGCNCGVGRRGQPLDATDRCCYVHKCCYKKLTGCNPLTDRYSHSLKNKTIVCGENKPCLKEMCECDKALAICLGKNVNTYNKNYKITMKMFCKKPDAC
What is the function of this protein?
Snake venom phospholipase A2 that lacks enzymatic activity.  Is myotoxic, and displays edema-inducing activities (PubMed:9056257).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog Bsc-K49, svPLA2 homolog, Myotoxin I.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SFM1_YEAST
Sequence: MKYIIEHMEEGFSEWVILEYSQILREVGAENLILSSLPESTTEKDIPQRLLKLGLRWTTKDLKGINEDFKDLELLKDGRVCLLDPRATIDLQPEDATKFDYFVFGGILGDHPPRDRTKELKTAYPNLLISRRLGDKQMTTDTAIRTTQLIIKDRIAFEDIKFIDYPEFRFNKNEATEMPFRYVLDKEGKPILPEGMLDLIKKDSAQSLDDLLM
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that monomethylates ribosomal protein S3 (RPS3) at 'Arg-146'.
What are the official names of this protein?
Protein arginine N-methyltransferase SFM1, SPOUT family methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase SFM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BACC2
Sequence: MPRVKGGTVTRQRRKKVIKLAKGYYGSKNTLFKVANQQVMKSLMYAFRDRRQKKRDFRKLWITRINAAARMNGLSYSRLMHGLKNAGIEVNRKMLADLAVHDEKAFAELATVAKNNIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS4_STRPM
Sequence: MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SC61B_CANLF
Sequence: MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER) (PubMed:8107851).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides (PubMed:8107851).  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex (PubMed:36261528).  The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER (By similarity).
What are the official names of this protein?
Protein transport protein Sec61 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ENOPH_DROGR
Sequence: MAQAESSTEVVLVDIEGTTTSISFVHDVLFPYAKENAKDYLLETWQTDETKLIVKELQQLPHYTEYAANLATQPTLDAEAISRFVRYLIERDLKVTPLKTLQGLIWAKGYADGQLRGHVYEDVAGAFGKWHQDGIRIAVYSSGSVAAQKLIFQHSIAGDLLPHLSAHFDTHIGHKQQSESYTKIAESLQVQPQHVLFLTDVPQEAAAARAAGMLTTLLERPGNAPLSEEERKKFSSVADFTGIVV
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CMOA_SHEON
Sequence: MNASQDTIYAQVSEHISDFQFDSRVAGVFSDMIRRSVPGYTQIINTIGDFADRFVKPNTQVYDLGCSLGAATLSIRRQIQGRDCRIVAVDNSESMVIRCQENLNAYVSDTEVELICGDIRDIHIENASLVVLNFTLQFLPPEDRDALIAKIYQGLNPGGLLVLSEKIRFDDAPIQSVLEELHLDFKRANGYSELEISQKRSALENVMKPDTLSTHQQRLTHQGFSHFSTWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: ATX10_BOVIN
Sequence: MAAPRPPPGRLSGVMMPAPIQDLEALRALTALFKEQRNRDTAPRTIFQRVLDILKKSSHAVELACRDPSQVEHLASSLQLITECFRCLRNACIECSVNQNSIRNLGTIGVAVDLILLFRELRVEQDSLLTAFRCGLQFLGNIASRNEDSQSVVWMHAFPELFLSCLNHPDRKIVAYSSMILFTSLNSERMKELEENLNIAIDVVEAHQKQPESEWPFLIITDHFLKSPELVKAMYAKMSNQERVTLLDLMIAKIVGDEPLTKDDAPVFLSHAELIASTFVDQCKIVLKLTSEQHTDDEEALATIRLLDVLCEKTANTDLLGYLQVFPGLLERVIDLLRLIHVAGNDSTNIFSACASIKADGDVSSVAEGFKSHLIRLIGNLCYKNKDNQDKVNELDGIPLILDSCGLDDSNPFLTQWVVYAIRNLTEDNSQNQDLIAKMEEQGLADASLLKKMGFEVEKRGDKLILKSTSDTPQL
What is the function of this protein?
Necessary for the survival of cerebellar neurons.  Induces neuritogenesis by activating the Ras-MAP kinase pathway.  May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
What are the official names of this protein?
Ataxin-10, Spinocerebellar ataxia type 10 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ataxin-10 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: DCUP_CERS4
Sequence: MTKTMLRALKGETLPTPPIWLMRQAGRYLPEYRATRAQAGDFLSLCYTPDLAAEVTLQPIRRYGFDAAILFADILLLPQALGADLWFETGEGPRMSTITDMAGVTALKGRDDIHETLAPVYETCRILARELPKETTFIGFAGMPWTVATYMIAGRGSKDQAAAHKLKDTDRPAFEALMDRVTEATIEYLAKQVEAGCEVVKLFDSWAGSLKGQDFEDFAVAPAKRIVSELKARFQGLPVIAFPREAGEGYIGFAEKTGADCVAIDNSVSPEWAAEKVQAGRTCVQGNLDPKYMVTGGEELVQATKRVVEAFRNGPHIFNLGHGITPEADPENVTLLVETIRGK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR7_TYRGL
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-7, FMRFa-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMC_VIBC1
Sequence: MSAYIAPSQIAQRQLEYFNGKHVLVAGEVEDLFPLELVAHCESVEVFTSNYSYYRQIRTSDKVKSHFGSEFDIETQADMVLLYWPKAKAEAEYLLAMLMTKLGINTEIVVVGENRSGIKSIEKMFKEYGPVKKYDSARRCSFYWGTCLNEPKPFNQADWFKSYEITLGEQSLTVKSLPGVFSHGEFDLGSRLLLETLPKLSGKVLDFGCGAGVLGAFMAKANPEIAIEMCDINAYAITSSQATLEANGLSGRVFASDIYSDTAKDYRFIVSNPPFHSGLDTNYNAAETLLGQAPKYMTANGEMIIVANSFLQYPPIIEKAFNNCETLNKTNKFSIYYAKKS
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.