PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_STAAW
Sequence: MNTIRNSICLTIITMVLCGFLFPLAITLIGQIFFYQQANGSLITYDNRIVGSKLIGQHWTETRYFHGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNTELIARMKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADARHISTSRVADLIQHRKQRGVLTNDYVNVLELNIALDKMKD
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CINAL_SHEAM
Sequence: MKLEMICTGEEVLAGQIVDTNAAWFANLMMENGIEVQRRVTVGDRLEDLVAVFQERSLHADVILVNGGLGPTSDDMSAEAMAKAKGESLVENAEWAERLHDWFTRHGREMPKSNIKQAWLPESAVMVDNPVGTACGFRVKLNRAWLFFTPGVPFEFKQMVEEQFLPFVKATFDAGSQVALRKLLTLGRGESSLADELEAMALPAGITLGYRSFMPYIEIKVFARGVEAIKALGAVTDEIAARLGNVVVAHNRTSLEEEIHARLNNSGISLSVAESCTGGLITSQLVGFPGSSSYLHQGLVTYSNESKVRVLGVSPQTLDDYGAVSIQTVEEMAKGARAILDSDFALATSGIAGPDGGTEEKPVGTVAIALATKGGVYSQMVKLPRRSRDMVRKVSAAVAYDMLRRELNGEAVIVDYSSISRYPK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ATPF1_METPB
Sequence: MLLTAEFWVAVAFVAFLVIVWRVGGFSMMTSGLDSRAKRVRHELDEARRLREEAAAVLADYKRRRTEAEREAEAIVAGAREDAERIAAEGHARLNDFVARRTKAAEAKIAQAEAQASAQVRAAAADAAVKVSETLLRERLQGGAAQDLVRASLGDVKSRLQA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MURD_PELTS
Sequence: MLKDFTRKKVLVIGAGRSGLAVSRFLVKKGASVVLADAGKPDYPDGELEDLTAAGVELSLGGYPGVGKESVDLVVVSPGVPLTVEPVRAAVREGIPVTGELELAYYFTRSPIVAVTGTNGKTTTTTLIGEIFKDAGMNTLVGGNIGSPLIAEVERYGPDDVIVAEVSSFQLETASTFRPKVGVVLNITPDHLDRHGTMGNYAATKARMFANQGPGDFAVLNCDDPLAASLKAGVRSRVIFFSRRKELKEGVWVSGGMIVASLNGHREVVCRSDELGLPGAHNLENALAAVAAAKAMGIESNSLAGTLRRFKGVAHRLEFVAEVDGVRYINDSKGTNPDAAIKALESYGEPIVLIAGGKNKGSDFREFARKVKEKAKVLVVLGQSAGLIAEAARAEGFENILYADGFREAVLLARRVARPGDIVLLSPACASWDMFKSFEERGDLFKEIVLSLKKG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMDA_PELUB
Sequence: MKNFSIAKSRRLRSTPYTSRIEKQGVTAYTIYNHMLLPAAFGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIIDENGNLVNDPVVLKLDENKWWISIADSDVIFFAKGLASGHKFDVKIVEPVVDIMAIQGPKSFALMEKVFGKKITELKFFGFDYFDFEGTKHLIARSGWSKQGGYEVYVENTQSGQKLYDHLFEVGKEFNVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVSLDSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACYSPHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI
What is the function of this protein?
Major contributor to the demethylation of dimethylsulfonioproprionate (DMSP).  Demethylates DMSP to methyl-mercaptopropionate (MMPA).
What are the official names of this protein?
Dimethylsulfonioproprionate demethylase DmdA.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. DmdA subfamily.
Protein: METK_PYRIL
Sequence: MIVIEKVDKTPVVKRLVEIVERKGQGHPDYIADGISEWVSRYLSRYYLEHFGIILHHNVDKTLVVGGQAAPRFGGGEVLQPIYILVSGRATYEVRTKDGVIKVPLGTLVMQAARDWIKQHFRFLDPDTHVVIDYKIGQGSADLVGIYDLGVKSVPLANDTSVGVGYAPLTPLEQLVYKTERLLNSRDFKAKYPEVGEDVKVMGVRVGKEVKLTVAAAMISKLVKDKSHYLSVKEDVKKAVEDLASKVAPEYNIEVVVNAADKPEHGIFYLTVTGTSAEHGDDGMTGRGNRANGLITPMRSMSLEAAAGKNPVSHVGKIYNVVAQRIADKVYNQVKDIIEVYVEIVSQIGKPINEPKILNVEIIKSGELTGEVRNEVEAIAREEIEKITQITDYILRGEVSLY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: DNAG_MYXXA
Sequence: MGVVIPEHKIQEVLERVDLVGLISRHVDLKKAGREWKACCPFHQEKTPSFYVVPEKRFYFCHGCRASGDAVSFVQRYLGKTFLDAVRDLARELGVDLEAEQDPSMRERQQIKEATDQAAEHFRAMLWQQDEGRSARAYIASRGVSDETAMAFGLGWAPLEWASLTERFQKLGMLEWAAKAGLVLKRNSGDGYYDFFRSRVMVPIRAPEGRPIAFGGRLIGADEGPKYLNSRESRLYNKSETLFGMDQSRDEIRKRKAAVLVEGYFDALGLHQVGVRHAVALCSTNLTAGHMQVLKRAEARELILLLDGDSAGLAAVERLSGPLLAAGATARVALLPQGDDPDTFARREGQEGVERLLEGAHPLTSHLFASLLPEGKAASFEEKMAALERLKPVVGQVPVGLVRATLFSAVAEHFGWRPADVEAALRSKVPLPKPAGGDAPPSSPNRPAPPLEKPPPALECFYVGAVLKEPRLMARDTFRVCDELSHMGLRMALAHATSGHGANDALFESSEAVKRGIESALRQLPSEPVPLEAAFLSICREIMVRRIDERLVYIKRATEQTPGAFDLTEETRQLLVERVELLALKKRVLEELKPASSGTKAPMQPV
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: PSF2_KLULA
Sequence: MALPRDLSIGFSPQEIQFLIENEPTRIMPRITTRKTKKQLAKDPGAQWSLITCDDSTVNNMVAMNSCEVTLWLALLLKQQGKCNVVVPSWLTLQQLEKYLDFELKNPSRFSNLPWNWLVVSSLLFARCSDDFQDPVHLLRSKVQDLREVRLGKVNKGLQYLNESHLQLENLSLMEINEMRPYACGIMDKLRTIHDSSNDTT
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDLI7_MOUSE
Sequence: MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLNIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKALTPPADPPRYTFAPSASLNKTARPFGAPPPTDSTLRQNGQLLRQPVPDASKQRLMEDTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEFMKKSSQVPRTEAPAPASTIPQESWPGPTTPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQNRTSIVQAAAGGGTGGGSNNGKTPVCHQCHKIIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPSCYDVRYAPNCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGAPYCERDYEKMFGTKCRGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDKPLCKSHAFSHV
What is the function of this protein?
May function as a scaffold on which the coordinated assembly of proteins can occur.  May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues.  Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e. g.  embryonic flat bones mandible and cranium), and endochondral bone formation (e. g.  embryonic long bone development).  Plays a role during fracture repair.  Involved in BMP6 signaling pathway (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 7, LIM mineralization protein, LMP, Protein enigma.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity).
Protein: FABD_MYCBO
Sequence: MIALLAPGQGSQTEGMLSPWLQLPGAADQIAAWSKAADLDLARLGTTASTEEITDTAVAQPLIVAATLLAHQELARRCVLAGKDVIVAGHSVGEIAAYAIAGVIAADDAVALAATRGAEMAKACATEPTGMSAVLGGDETEVLSRLEQLDLVPANRNAAGQIVAAGRLTALEKLAEDPPAKARVRALGVAGAFHTEFMAPALDGFAAAAANIATADPTATLLSNRDGKPVTSAAAAMDTLVSQLTQPVRWDLCTATLREHTVTAIVEFPPAGTLSGIAKRELRGVPARAVKSPADLDELANL
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: ATPA_ECO27
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DP2L_METKA
Sequence: MNRAREELDRYRETLEEVSSRFVDVATKARQRREDPKPEPEVMLATSIGERVEGLLQVENVADRLEELEEELGDREEATFRIVEEVIKGELKVKGDLPLHKRIDYAVRIGLAVLTEAVVSAPLEGIAAVEIRERGTGHRVVDESEPPHEEPKLVCTECGKEVDPENCYLAVKYAGPIRAAGGTAAALSALLADYARQVAGLPRFNPDDFDHDLVGRYVEEVVTYLDKVGSFQYNPSEEEVELVAKNIPIEIDGEPTEEVEVQGHRDIPHLPNQLRGGALLVICEGICQKAPKLIKRVEKYGIDGWEFLEKLVNKGSDDEEEGEEEKTKIKPNDKYMGELVAGRPLLSHPSAKGGFRLRYGRARNTGFAAVGVHPSLMYVTKGFIVIGTQLKVERPGKAACVLPVTEIEPPVVKLRDGSVVRLDDPREAKELVEKDEIEEILDLGEMLVAVGEFIENNHPLVPPAYCPEWWVKEVPDVVKVIGLRKNLPNDVFEKLKDVPLKRLVKEASRLSGNGNNLDGFLNGPVKVARSIVELVRKEVIPRLSSPERMSVEEAIELSREYGVPFHPKYTFLWHDVKPKDVDELREALEVAGSEWGNLRVEFENDGEIKRILEDLLVPHRLEDDTIVVEEPWASALLAQLGYDPESGEFREQDEDLDYLLDYLVIRDETCRYVSKLAGFPIREKAPTRIGARMGRPEKARERKMSPPPHVLFPIGIAGGNQRDIMKFHRGESEDTDRVEVCYRICPECDRLVPYRVCPFCGTETVQYCNRCDEPADECDCEEPDPVVRADIERNDDPYSSLPVRELVRRAEEEVGTTDTLKGVKGMTSRLKMPEPLQKGILRAKRDLFVFKDGTLRFDCNDCPLTHVRLKEVGLTPFKARLLGFERDINGDPVVSEDQVVELYPQDVVLPRKAAEWAVRVCQYLDDLLRKYYGLEPVYGVEKPEDLIGHLIVTLAPHTSCGVVGRVVGIADINCWYNHPIINAARRRNCDGDEDAFMLLLDVLLNFSRLYLPDKRGGLMDAPLVLTAVVDPYEIDDEVWNMDVCGDYPLELYRKALEYADAGEAEELIERLEDRLDLPRGLQFTHDTEAIDLGPTVTRYSRLEKMEEKLEEQLDLARRIRAVDESDVAKIVLDSHFLPDIKGNLRKFGRQKFRCSRCNAKFNVPPLSGKCPRCGGDVLLTIYPATATKYLEPAKRLVEEFGTHDEEWRTIASEVELLEEEAKTLFGSDHSVSLKKFFGET
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: GIS3_YEAST
Sequence: MLLDVNTNHTLMHDAHVHEHCLIKSIRDDGALHSWSDSSKVFYPKSFYATATNKKNNKLASASMNKTATSNRTVSDEIYFHSTKPQFDGQGSAERTRTLTKRNSFKRTRILKARDDSELLNENRSSLMTPSLSSVMSQVRKTNSAKTLSGECPIHEGHLTQSIKRKFSEEAQSDCSSLSSSKLHPLTDDIADAVDLQTPAIGDEVLAEPVVPKMKIININDLDLFDDWEVKDLVDIFPPVYERRPRSSSALSLVSASSDAKLRPTSVDFQIIDKKGGKTSRRKSRSKSTTENMIYENDLVELEQWPSASPSPETDGSIASSELLPNKRIRQKSLNTNFLKLYSIETSCKRKSILPEVEVDDHLLKQLTYSEIRSLEIKKEPNVSTNDIKLALITRKKLWSDMVHETRNDLFGDSTPWNLHFVATTSNTEPSQGRESASEHATADLKSSLVRVHSDVKPWFNNGGTMLKPCGKLNLGKVTNKTSAPTREIQYVVKGWCDSRFL
What are the official names of this protein?
Protein GIS3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TOTE_DROYA
Sequence: MSYNRTLHSTTSILKMNSALQISCLLLVLGCLLGSGHGQSDAEFAAKSREISQIFGNPSVDKYTKVRNLPALVAFYEKYSSRLRLTAQEKKGIDNAIRQYRAQQNQKVDGVSAQGGTLFDILKKVVEVIIKVVV
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot E, Protein Victoria.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_RHORT
Sequence: MASLKDLRSRITSVKSTQKITSAMKMVAASRLRRAQDTAEAARPYTQRMERMLGNLAASTAGMAGASPLLGGTGKDNVHLIVALTANRGLCGGFNGSIIRATRTLVRELEAQGKTVKLLCIGKKGRDGLKREFPKQIIGGIADQSSKAIGFSDADRFSRLILDMFQAGEFDVCTLVYNRFQSAISQVVTRQQIIPFAVPTTVAAGNDNDRTAGPKAIYEYEPSEEEILADLLPKNVAIQVFRGMLESFASEQGARMTAMDNATRNAGDMIKKLSLTYNRTRQAQITKELIEIISGAEAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THII_BACVZ
Sequence: MNYDHILIRFGEISTKGKNRRSFIERLKQNIRLVLKDYKKVKYFSNRDRMSITLNGENPEEICSLLKNIFGIQSFSLAIKCESKLEDIKKTALAAIEGEYKPGNTFKVETKRAYKQFELDTNAMNAEIGGHILKNTDGLTVDVKHPDIPLRIEIREEATFLTIRNEKGAGGLPVGSAGKAMLMLSGGFDSPVAGFYAMKRGLSVEAVHFFSPPYTSERAKQKVMDLAGCLAKFGGSMTLHIVPFTKTQELIQKQIPENYTMTATRRLMLQIADRIREERKALAIITGESLGQVASQTLESMYAINAVTATPILRPLIGMDKTEIIEKSKEIGTYETSIQPFEDCCTIFTPPSPKTRPKKEKIEHFESFVDFEPLIAEAAAGIETITVYSEQEAHDKFAGLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH2_FUSNN
Sequence: MQKIIEINGSNLTIEDVVAVARYGAKVKLDEKQKDKILESRKYVEEALSNKMPIYGINTGFGKFENVPISEEELELLQKNLIYSDACGVGEAFDTEIVRAMMILRANAISKGFSGVMIETVECLLNMLNAGVHPIVRSKGSVGSSGDLCPLAHMVLPMIGEGEAEYKGEILSGKEAMKKAGVSTITLKAKEGLALINGTQAMMGNAVLAVYDAEKLLKQADIVASLSIDALGGIIDAFDERIHLIRPHKGQIYSAENLRKLLKGSKRTTRQGEKRMQDAYSLRCTPQVHGASRLAFDYVKQTVETEINSVTDNPLIFPGENGACISGGNFHGQPIAIAMDTLGILMSEIANISERRIEKLVNPALSHGLPAFLVKNGGINDGFMIPQYVAAALVSENKVLAHPASVDSIPTSANQEDHVSMGTIGARKARTIVDHAQHVVSIELLCAAQAADFWDSKNLGVGTKEAYRTLREKVDFMENDVIFYPLMDKSFEIIKSAILLANVEKIIGLLK
What are the official names of this protein?
Histidine ammonia-lyase 2, Histidase 2.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPS1_MOUSE
Sequence: MEIPGSLCKKVKLSNNAQNWGMQRATNVTYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGDNIRQGLNKNLGFSPEDREENVRRIAEVAKLFADAGLVCITSFISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQERDIVPVDASYEVKELYVPENKLHLAKTDAEALPALKINKVDMQWVQVLAEGWATPLNGFMREREYLQCLHFDCLLDGGVINLSVPIVLTATHEDKERLDGCTAFALVYEGRRVAILRNPEFFEHRKEERCARQWGTTCKNHPYIKMVLEQGDWLIGGDLQVLDRIYWNDGLDQYRLTPTELKQKFKDMNADAVFAFQLRNPVHNGHALLMQDTHKQLLERGYRRPVLLLHPLGGWTKDDDVPLMWRMKQHAAVLEEGILDPETTVVAIFPSPMMYAGPTEVQWHCRARMVAGANFYIVGRDPAGMPHPETGKDLYEPTHGAKVLTMAPGLITLEIVPFRVAAYNKKKKRMDYYDSEHHEDFEFISGTRMRKLAREGQKPPEGFMAPKAWTVLVEYYKSLEKA
What is the function of this protein?
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway.  The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase).  In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway (PubMed:7493984).  Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells (By similarity).
What are the official names of this protein?
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPS synthase 1, PAPSS 1, Sulfurylase kinase 1, SK 1, SK1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the sulfate adenylyltransferase family.
Protein: Y1579_STAAS
Sequence: MMDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVKQFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SAS1579.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: NNRE_USTMA
Sequence: MPFSTPAQPSCSAASPLRLRYIDASTAQKIDEDLMSASGGFSLDQLMELAGLSCAQAVFECYPPTKYPNVLVACGPGNQGGDGLVAARHLYHFGYEPVVWYPKQGKTELFSRLKVQLHNLGLPFVSQDDFQDALEEADVVLDSIFGFNFKGDVREPFRAPLEILKYESRIEFEARKKMPPIVSVDIPSSWHVELGNVNKAFTPSVLISLSAPKLGALAFAGRHFLGGRFLPEDLEAKFDLQLPDYPGTEQVIEITGAKPLQTQEADL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: APOC1_ARCGZ
Sequence: MRLFLSLPVLVVVLAMVLEGPAPAQAAPEISSTLERIPDKLKEFGNTLENKARAAIESIKQSDLPAKTRNWFSETFNKVKEQLKTTFS
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRPC1_CORGL
Sequence: MSDSQVRKGLNGVISDYTSISKVMPESNSLTYRGYAVEDLVENCSFEEVIYLLWFGELPTTEQLRTFNTTGRSYRSLDAGLISLIHSLPNTCHPMDVLRTAVSYMGTFDPDPFTRDADHIRSIGHNLLAQLPMVVAMDIRRRSGEEIIAPDHNKGIASNFLSMVFGNDDGSVANSADDIRDFERSLILYAEHSFNASTFSARVISSTRSDTYSAITGAIGALKGPLHGGANEFVMHTMLDIDDPNNAADWMGKALDRKERIMGFGHRVYKNGDSRVPSMEKSMRSLAARHRGQKWVHMYESMQEVMEARTGIKPNLDFPAGPAYYMLGFPVDFFTPLFVLARVSGWTAHIVEQFENNALIRPLSAYNGVEEREVVPISERT
What is the function of this protein?
Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA.  Also catalyzes the condensation of oxaloacetate with propionyl-CoA but with a lower specificity.
What are the official names of this protein?
2-methylcitrate synthase 1, 2-MCS, MCS, Citrate synthase 1, CS.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: LBD12_ARATH
Sequence: MGGPGSSPCASCKLLRRRCAKDCIFAPYFPPDDPHKFAIVHKVFGASNVSKMLQELPVHQRADAVNSLVFEANARVRDPVYGCVGAISYLQNQVSQLQMQLAVAQAEILCIQMQNEPTLQSHHQVLELDQDHKALLLNNNNINNCNTNNNNNNFGYAMSSGQFNSNFASPSSIMQMQMQMQMQDPLKQESLWT
What are the official names of this protein?
LOB domain-containing protein 12, ASYMMETRIC LEAVES 2-like protein 5, AS2-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: CPS1_MAIZE
Sequence: MAAAVVVRRAAGLIPLLSSRFGARMPLHRALSQIPPPRFCRLLSQQTKPFSASASNGAATDRTRELRLYNTKSRKKEQFRPRIPGREVGMYVCGVTPYDDSHIGHARAYVAFDVLYRYLRYLDYEVRYVRNFTDIDDKIIARANQLGEDPFSLSKRFSDDFLSDMANLQCLPPSVEPRVSDHVDEIINMIKQILDNRCAYVVGGDVYFSVDNFPEYGELSGRKLDDNRAGERVAVDERKRNPADFALWKAAKDGEPWWDSPWGPGRPGWHIECSAMSAHYLGHSFDIHGGGEDLIFPHHENEIAQSRAACCDSTINYWIHNGFVNVNSQKMSKSLGNFVTIRKVIEMYHPLALRMFLLGTHYRSPINYTIEQLNVASDRLYYTYQTLRDCEEICQHQQSNTGNPLPANTLNYIQKLHDEFETSMSDDLHTSVALAAMSEPLKVMNDLLHTRKGKKQDKRLESLSALEEKIRVVLSVLGLLPSSYHEALQQLRDKALRRASITEELVVQKIEERTAARKAKQYEKSDEIRKELAAVGIALMDGPDGTTWRPSLPLPEEEAVLAKT
What is the function of this protein?
Nuclear genome-encoded factor required for normal assembly of chloroplast polysomes.
What are the official names of this protein?
Cysteine--tRNA ligase CPS1, chloroplastic/mitochondrial, Chloroplast synthesis protein 1, Cysteinyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion. Note=The cps1 mutant phenotype resembling other non-photosynthetic mutants, CPS1 may function solely in chloroplasts.
Protein: F151B_HUMAN
Sequence: MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENVKRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVISFFPDVTFSLGWTTGWHPEKVNEGYSWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVEDLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL
What are the official names of this protein?
Protein FAM151B.
What is the protein family that this protein belongs to?
Belongs to the FAM151 family.
Protein: Y1283_BACC4
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFEAQDEQLESIVNELHTIASKTNPFTLHVGKVGSFAPVNNVLYFKVEKTPELTFLNEEMHSGLFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BCB4264_A1283.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: DAPB_ECO45
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_ECODH
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.