PharMolix/UniProtQA huggingface dataset:
Protein: SYP1_BACC1
Sequence: MKQSMVFSPTLREVPADAEIKSHQLLLRAGFMRQNASGIYSFLPFGLKVLHKVERIVREEMERAGAVELLMPAMQAAELWQESGRWYSYGSELMRMKDRNAREFALGATHEEVITDLVRDEVKSYKKLPLTLYQIQTKFRDEQRPRFGLLRGREFLMKDAYSFHATQESLDEVYDRLYKAYSNIFARCGLNFRAVIADSGAMGGKDTHEFMVLSDVGEDTIAYSDTSDYAANIEMAPVVATYTKSDEAEKALEKVATPDQKAIEEVSAFLNIEAEKCIKSMVFKVDEKLVVVLVRGDHEVNDVKVKNVYGASVVELASHEEVKELLNCEVGSLGPIGVTGDIEIIADHAVASIVNGCSGANEEGFHYVNVNPERDFKVSQYTDLRFIQEGDQSPDGNGTILFARGIEVGHVFKLGTRYSEAMNATFLDENGKTQPLIMGCYGIGVSRTVAAIAEQFNDENGLVWPKAVAPFHVHVIPVNMKSDAQREMGENIYNSLQEQGYEVLLDDRAERAGVKFADADLFGLPVRVTVGKKADEGIVEVKVRATGESEEVKVEELQTYIANILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase 1, Prolyl-tRNA synthetase 1, ProRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_PELPD
Sequence: MLNVAIVGASGYTGLELLRILYAHPQVAVTCVTSERSAGKRIDEVFPTLRDRCSLVLENLEPVRVSQKADLIFTALPHKAAMAVMPTFMELGKTVIDLSADYRLSDAEVYGAWYEPHLNPELLKSAVYGLPEIRRESIRGKKLVANPGCYPTSITLGLAPLLKNGMIDLKSIIADSASGVTGAGRGAKVDSLYCEVNEGYKAYGVGGVHRHTPEIEQELSLLAGEKVTLTFTPHLVPMDRGILSTIYATPLKGVTTEELNELYRNFYAEEPFVRVLPLGSLPSTAFVRGSNFCDIAPVVDKRTGRVIVVSAIDNLMKGASGQAVQNMNIVCGFYESAGLSGLALFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_MYCS5
Sequence: MELKVNIAIDGPSGVGKSTVSKLIAKKLNYTFINSGSIYRTIAYHVIKNDIDINNEKDVISSLDSLEFSLSKNEELFYKGENITLILRSEQISISTPVVSKIPEVREFVTSYIQKMTKGKKGFIIDGRDTTFKVMPHADVKIFLWATAEERAQRRVDQNHQLGYNSNYDEVLYEIKKRDHQDMNREHDPLHKTEDSILIDCTNMKIDEVVNKIISLIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_STRS2
Sequence: MKRIAVDAMGGDHAPQAVVEGVNQALAAFPDIEIQLYGDEAKIKQYLTATERVSIVHTTEKINSDDEPVKAIRRKKEASMVLATKAVKDGQADAVLSAGNTGALLAAGVFVVGRIKNIDRPGLMSTLPTMDGKGFDMMDLGANAENIAHHLYQYGILGSFYAEHVRGVKQPRVGLLNNGTEDTKGTPVHQEAYKLLAEDKSINFIGNVEARELLNSVADVVVTDGFTGNAVLKTIEGTAKSIVGQLTGSIKNGGLRAKLGGLLVKPTLKKALGAMDYKTAGGAVLLGLKAPVIKAHGSSDAQSIFYTIKQTRSILEAGIVEKSVAKFSVVEESHD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ACEK_PSEP1
Sequence: MSQPWPAVEIARMILAGFDDYRDHFQRITLGARQRFEQARWQDIQQAAAARINLYEEKVAEVNGWLRQAFAAEVLLDVEQWPLVKNAYIHLIDPRLDDELAETWYNSLFCSLFSHDLISDGCMFIHTTRPSMRGRERAAQTRTYRLDGSLRNLLRAVFADYPFDMPYGDLEGDLARLEEQLRECLPDWVCKDPALAVELFVPVLYRNKGAYLVGRLYNSDEQWPLVIPLLHREGHGIEADALITDEAEVSIIFSFTRSYFMADVPVPAEFVNFLKRILPGKHIAELYTSIGFYKQGKSEFYRALINHLASSDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFSPSKTVDRATVIDKYRLVKSVDRVGRMADTQEFADFRFPRSKFEPDCLAELLEVAPSTVALEGDTVLIRHCWTERRMTPLNLYLEQATEGQVLEALEDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISFLTEVNFRHIPPPRYPEDEMSGEPWYSIGPHDVFPEEFPPFLFADMGQRRLFSRLHGELYDADYWKGLQAAIREGKVIDVFPYRRKAR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_PROM3
Sequence: MSLISRLRAVVAGDDYLDSDYDDLDYDTDDHMDADHRSDHASGGALATPSDSSPFDLGGGFSGSNVIGMPGVGSTSAEVNLMEPRSFDEMPRAIQALRERKTVILNLTMMEPDQAQRAVDFVAGGTFAIDGHQERVGESIFLFAPSCVTVSNTSYDEASAPSMVSQDHDSVPSSSQQTGAAPVPAWEVTRAGGL
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GLND_NITHX
Sequence: MDLATTNDAAGAGNDFDTARITGDIDALAAKHAGHEDVFRAAVSRLLKAELAKVRDAAQAKLLRDRHGRRCAERLCFIQDEIIRLSFSAATRHLYHSPIPSDGERMAVVATGGYGRGLMAPESDIDLLFILPYKQTAWGEQVAEAILYCLWDMGLNVGHATRSVNESIRQARRDMTVRTGILETRFLAGDRALYDELVTRFDTEVVQGTAAEFVTAKLAEREERHRRAGQSRYLVEPNVKDGKGGLRDLHTLFWIAKYVYRVHESRELLGCGVFDVREYRTFRRCADFLWSVRCNLHFATGRAEERLSFDLQREIAVRLGYTSHPGMQDVERFMKHYFLTAKDVGDLTAILCAKLEDQQAKPAPVLGRMMSRRRPGTELRRVPEGDDFIIDNNRINLAAPDVFKRDPVNLIRVFRLAQKNNLAFHPDALRTVTRSRRLINAQLRENPEANRLFMEILTSNDAETVLRRMNETGVLGHFIRAFGKIVSMMQFNMYHHYTVDEHLLRCIGILQDIERGGNDELALASELMRKIHPEHRPVIYITTLLHDIAKGRPEDHSIAGARVARRLCPRLGFNASDTELIAWLIEQHLTMSKVAQSRDLSDRKTIENFAAVVQSVEQMKLLTILTTADIRGVGPGVWNGWKAQLLRTLYYETEPVLTGGFSEVNRVQRIAEAQAEFRAAFTEWSEPELNAYIARHYPAYWLKVDLAHKIRHARFLRASEQGGRKLNINVGFDEARGVTELTIFAADHPWLLSIIAGACASAGANIVDAQIYTTTDGQALDTIAISREYDRDEDEGRRAARIGEIIEQVIDGRLRLPDVVARRAAGKTRLRPFVVEPKVIVNNQWSDRHTVIEVSGLDRPGLLFQLTAAISKLNLNIASAHVATFGERARDVFYVTDLLGARITAPTRQAAIKRALIHLLANGGAAEQSVG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RSMA_CORDI
Sequence: MEDQASAQLLGPVEIRQLAEKLDVTPTKKLGQNFVHDPNTVRMIVSAADLNSDDHVIEVGPGLGSLTLALLDTAQKVTAVEIDPRLAQQLPLTVAERAGQFADRLNLIHKDALTVAPDDIDHPTALVANLPYNVSVPVLLHLLQIFPTIRRVLVMVQAEVADRLAADPGNKVYGVPSVKASFYGNVRRAGSIGKNVFWPAPKIESGLVRIDVFDPEHQPWPVTDDMRKAVFPLIDSAFAQRRKTLRAALSGHFGSGPAAEEALRTAGIDPILRGEKLDIADFVRLARVTAAQEQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y627_METJA
Sequence: MEIDVKSPDLIINTIRGNEKIYFDKSIFEESLDNKFEIIQYLMKILERFLKIYDNHIKEIKLLIDSENHPEPHLIVVIKFKNKENIFKISEQIENKIYENPKSKNVLVYPITGGTDV
What are the official names of this protein?
Uncharacterized protein MJ0627.
Protein: CLPS_MYCBO
Sequence: MAVVSAPAKPGTTWQRESAPVDVTDRAWVTIVWDDPVNLMSYVTYVFQKLFGYSEPHATKLMLQVHNEGKAVVSAGSRESMEVDVSKLHAAGLWATMQQDR
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RS9_PAPAN
Sequence: MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: RL15_ANOGA
Sequence: MGAYRYVQELYRKKQSDVMRYLLRIRVWQYRQMTRFHRAPRPSRPDKARRLGYKAKQGFSIFRIRVRRGGRKRPVPKGCTYGKPKSHGVNQLKPYRCLQSVAEERVGRRLGGLRVLNSYWVAQDAAHKYFEVIMVDPAHNAIRRDPNVNWICNAVHKHRELRGLTSAGKSSRGLGKGYRYSQTIGGSRRACWRRRNRLHLRRYR
What are the official names of this protein?
60S ribosomal protein L15, RL10.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: UBAC2_MACFA
Sequence: MFTSTGSSGLYKAPLSKSLLLVPSALSLLLALLLPHCQKLFVYDLHAVKNDFQIWRLICGRIICLDLKDTFCSSLLIYNFRIFERRYGSRKFASFLLGSWVLSALFDFLLVEAMQYFFGITAASNLPSGFLAPVFALFVPFYCSIPRVQVAQILGPLSITNKTLIYILGLQLFTSGSYIWIVAISGLMSGLCYNSKMFQVHQVLCIPSWMAKFFSWTLEPIFSSSEPTSEARIGMGATLDIQRQQRMELLDRQLMFSQFAQGRRQRQQQGGMINWNRLFPPLRQRQNVNYQGGRQSEPAAPPPLEVSEEQVARLMEMGFSRGDALEALRASNNDLNVATNFLLQH
What is the function of this protein?
Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (By similarity).  In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (By similarity).
What are the official names of this protein?
Ubiquitin-associated domain-containing protein 2, UBA domain-containing protein 2, Phosphoglycerate dehydrogenase-like protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NCASE_PSEAE
Sequence: MSRSAFTALLLSCVLLALSMPARADDLPYRFGLGKADITGEAAEVGMMGYSSLEQKTAGIHMRQWARAFVIEEAASGRRLVYVNTDLGMIFQAVHLKVLARLKAKYPGVYDENNVMLAATHTHSGPGGFSHYAMYNLSVLGFQEKTFNAIVDGIVRSIERAQARLQPGRLFYGSGELRNANRNRSLLSHLKNPDIVGYEDGIDPQMSVLSFVDANGELAGAISWFPVHSTSMTNANHLISPDNKGYASYHWEHDVSRKSGFVAAFAQTNAGNLSPNLNLKPGSGPFDNEFDNTREIGLRQFAKAYEIAGQAQEEVLGELDSRFRFVDFTRLPIRPEFTDGQPRQLCTAAIGTSLAAGSTEDGPGPLGLEEGNNPFLSALGGLLTGVPPQELVQCQAEKTILADTGNKKPYPWTPTVLPIQMFRIGQLELLGAPAEFTVMAGVRIRRAVQAASEAAGIRHVVFNGYANAYASYVTTREEYAAQEYEGGSTLYGPWTQAAYQQLFVDMAVALRERLPVETSAIAPDLSCCQMNFQTGVVADDPYIGKSFGDVLQQPRESYRIGDKVTVAFVTGHPKNDLRTEKTFLEVVNIGKDGKQTPETVATDNDWDTQYRWERVGISASKATISWSIPPGTEPGHYYIRHYGNAKNFWTQKISEIGGSTRSFEVLGTTP
What is the function of this protein?
Catalyzes the cleavage of the N-acyl linkage of the ceramides (Cers) to yield sphingosine (Sph) and free fatty acid at an optimal pH of 8-9.  Also catalyzes the synthesis of Cers from Sph and fatty acid.
What are the official names of this protein?
Neutral ceramidase, N-CDase, NCDase, Acylsphingosine deacylase, N-acylsphingosine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the neutral ceramidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: LRGA_BACAC
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDEKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASNA_ECOBW
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLELEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHA_SALAI
Sequence: MAEQHTGVGRQRGARPWPRPRRVATLSVHTSPLHQPGTGDAGGMNVYILEVARRLAEADVEVEIFTRATSADVPPVVEMMPGVHVRNIISGPLGGLTKEELPGQLCAFTAGVLRAEASRAAGHYDLIHSHYWLSGQVGWLAKERWGVPLVHTAHTLAKVKNAQLAAGDRPEPKARVIGEEQVVAEADRLVANTKTEAGDLIDRYDADPTRVEVVEPGVDLARFTPAAGDRSRAQALARRRLGLPERGYVVAFVGRVQPLKAPDVLIRAAAALRQRDPALAEELTVVVCGGPSGSGLDRPTHLIELAASLGVTDSVRFLPPQTGDDLPALYRAADLVAVPSYNESFGLVALEAQACGTPVVAAAVGGLVTAVRDQVSGVLVDGHDPAVWARTLSRLLPDTGLRATLAQGARRHACNFSWDRTVSGLLEVYGEAVAAYGPQSSELATCSC
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: GSA_LEPBP
Sequence: MNSETLFQRSKQVVPGGVHSPVRSFSSVGGTPIFFSEARGAYLKSVEGNDFIDYCLSFGPLLFGHRHPEIQEVVEDTVNKAWSFGACEPYSLELAEFITERIPWVEKIRFVNSGTEAVMSALRVARAATGRNKILKFDGCYHGHLDQLLVKSGSGLAGLSSSDSKGIGPEIIQNTLVLPLDDESKLEELFQREGSNIACLAIEPLPANYGLLPQRIEFLKKCRELTTKYGVLLLFDEVISGFRVSFQGMAGITGIIPDLVCYGKIIGGGFPVGAYAGKRELMDLVAPSGPVYQAGTLSANPIGMRAGLKTLTKAWTENPYPALESATKQLTDGILTLLSEKGDTNWEAVTFGSLFWLKGKTENPIRRIDQIPGTHKSNFATLFHKLLKQGVYLAPSGYEVGFLSTAHTNDIINLTLEKTKKALKD
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y18_BPT7
Sequence: MHNFKSTPPADSLSDDFTSCSEWCRKMWEETFDDAYIKLYELWKSRGQ
What are the official names of this protein?
Protein 1.8, Gene product 1.8, Gp1.8.
Protein: UBIQP_STRPU
Sequence: DSIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDSIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGQ
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSXB_SALPB
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKIAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: C76B9_PETHY
Sequence: MDYVNILLGLFFTWFLVNGLMSLRRRKISKKLPPGPFPLPIIGNLHLLGNHPHKSLAQLAKIHGPIMNLKLGQLITVVISSSVVAREVLQKQDLTFSNRFVPDVVHVRNHSDFSFVWLPVNSRWRTLRKIMNSSIFSGNKLDGNQHLRSKKVQELIDYCQKCAKNGEAVDIGRATFGTTLNLLSNTIFSKDLTNPFSDSAKEFKELVWNIMVEAWKTQFGGLLSFPLRKFDPQGIKRRMTNYFTKFLGLISGLIDERLKERNLRDNANIDVLDALLNISKRTQKRLTGIKSSSCLVSLFPTPFLPFIIICPFLYLLIFHRCKVSDLNGEGSYVGGRVQLNHTPLQIGCDRLTVSNKPRNYGDSYSSFRTCLQGLILHLNTLEWANGRTTSRIHTLLAKKHKKTISQHICTSKKIKIKKLLEHFLSFGAIVKKNLPIPPGGFSSSLFHVKWRKTLSCLGYIIPKDSQVLVSVWAIGRNSDLWENPLVFKPERFWESEIDIRGRDFELIPFGAGRRICPGLPLAIRMIPVALGSLLNSFNWKLYGGIAPKDLDMEEKFGITLAKAQPLLAIPTPL
What is the function of this protein?
Cytochrome P450 hydroxylase catalyzing the conversion of decanoate (capric acid) and dodecanoate (lauric acid) to their corresponding omega-hydroxy metabolites, 10-hydroxydecanoate and 12-hydroxydodecanoate, respectively; these hydroxylated components affect plant growth, including reducing root elongation.
What are the official names of this protein?
Lauric acid 10-hydroxylase, Capric acid 12-hydroxylase, Cytochrome P450 76B9.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: GCS2_BORA1
Sequence: MEQIPFVSSSPNTLGIELELQLIDPAGFDLAAASDELLAQLANHPVADRIKPEITRSMIELNSSVHEHPAGLLAEMREMRDALCEAADAVGVSVSGGGTHPFMRWQERTISDTPRFQYLAEMYGYLARQFTVFGQHIHLGVPSGDAAVRLVHGLSPYVPHFIALSASSPYREGVDTLFSCARLNAVNSFPLAGHLPPEVADWYHFEAHIAQLRASGLAESIKDLYWDIRPKPEFGTVEIRVCDTPLTVERACQLAAFAQALAVLLEREPSPPTQAWLAYRSNHFQACRFGLHGSYVTPGGQRVRLADHLKALFVRLMPVAEELGTTDILQSLRDEMQRGGNDARWLRAQFHRTRELSGTVEAMTQVFRGESAAQRRAPQAARRRIRASSEPLGPMSMWPERLH
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PAR6_CAEEL
Sequence: MSYNGSYHQNHHSTLQVKSKFDSEWRRFSIPMHSASGVSYDGFRSLVEKLHHLESVQFTLCYNSTGGDLLPITNDDNLRKSFESARPLLRLLIQRRGESWEEKYGYGTDSDKRWKGISSLMAQKPPKRSYSISNPEDFRQVSAIIDVDIVPEAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIFISRLVDGGLAESTGLLGVNDEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQRNTLSRGPSQQGTPNASEMSAATAAATGGIQRPMKMNGSSDGSYHPKQHDANDSDSGED
What is the function of this protein?
Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis (PubMed:8898226).  Required for localizing/ maintaining par-3 at the cell periphery (PubMed:9834192, PubMed:8898226).  Regulates mes-1 expression and/or localization pattern during early embryogenesis (PubMed:11003841).  Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca (PubMed:13129846, PubMed:15151982).  Plays a role in endosome and Golgi body positioning (PubMed:22634595).
What are the official names of this protein?
Partitioning defective protein 6.
What is the protein family that this protein belongs to?
Belongs to the PAR6 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Membrane-associated at the periphery of blastomeres up to about the 50 cell stage. Peripheral expression is asymmetric in the cells of the germline lineage P0, P1, P2 and P3 (PubMed:9834192). Asymmetric distribution in the 1-cell embryo is regulated by the cye- 1/cdk-2 complex (PubMed:17115027).
Protein: PURR_HAEDU
Sequence: MATIKDVAKLAGVSTTTVSHVINKTRFVAEETSKTVWNAVQKLNYSPSAVARSLKINTTKSIGMIITTSEAPYFAEIVLAVEEHCYQQGYSLFLCNTQNEPEKIQNHLDMLIKKRVDGILVMCSEYTRNSLELFNATNIPMVVMDWGKAHEKNDRIIDNSFNGAYLATRHLIDNGHKDIGVISGYLTKTICSERLEGFIKAMKEANLPIREEWILEGDFEPESGFEQMNNLLRLDKLPTAIFCFSDTIALGVLSALSEKGIAVPQDISIIGYDNTHSSRFFSPPLTTIHQSKSRLGVKALNLLLERIKLGHKEYQPHTIEFHPELVLRHSVRNLNKSEE
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.