PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_XYLFA
Sequence: MDRIIDTAATSEDEAIEVSIRPKRLADYLGQQPVREQMDIYIQATKARAEALDHVLIFGPPGLGKTTLSHVIAYELGVKLRVTSGPVIEKAGDLAALLTNLQPYDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTRTGLLTAPLRDRFGIVQRLEFYSPEDLARIVRRSAGILNIDCTTEGAAEIAQRARGTPRIANRLLRRVRDYAEVKAGGQITIEVAQAAMQMLKVDQGGFDELDRRLLHTIVEYFDGGPVGIESLAASLSEERGTLEDVVEPYLIQQGFLVRTARGRMATDKAYQHLALQPRERVSAFTDPEDLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YAP1_MOUSE
Sequence: MEPAQQPPPQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTASGVVSGPAAAPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPAPASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQELFRQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTPNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSEILDVESVLAATKLDKESFLTWL
What is the function of this protein?
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (PubMed:29400695).  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.  Acts via ARHGAP18, a Rho GTPase activating protein that suppresses F-actin polymerization.  Plays a key role in controlling cell proliferation in response to cell contact.  Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  The presence of TEAD transcription factors are required for it to stimulate gene expression, cell growth, anchorage-independent growth, and epithelial mesenchymal transition (EMT) induction.  Suppresses ciliogenesis via acting as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (By similarity).  In conjunction with WWTR1, involved in the regulation of TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation (PubMed:21145499).
What are the official names of this protein?
Transcriptional coactivator YAP1, Yes-associated protein 1, Protein yorkie homolog, Yes-associated protein YAP65 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization (By similarity). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (By similarity). At low density, predominantly nuclear and is translocated to the cytoplasm at high density. PTPN14 induces translocation from the nucleus to the cytoplasm (By similarity). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (PubMed:21145499).
Protein: TBC3K_HUMAN
Sequence: MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
What is the function of this protein?
Acts as a GTPase activating protein for RAB5.  Does not act on RAB4 or RAB11 (By similarity).
What are the official names of this protein?
TBC1 domain family member 3K.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.
Protein: PYRG_STRCO
Sequence: MPPKSSTTKHIFVTGGVASSLGKGLTASSLGMLLKARGLRVVMQKLDPYLNVDPGTMNPFQHGEVFVTNDGAETDLDIGHYERFLDRDLDGSANVTTGQVYSTVIAKERRGEYLGDTVQVIPHITNEIKHRIRRMATDEVDVVITEVGGTVGDIESLPFLETVRQVRHEVGRDNVFVVHISLLPYIGPSGELKTKPTQHSVAALRNIGIQPDAIVLRCDREVPTAIKRKISLMCDVDEAAVVACPDARSIYDIPKVIHTEGLDAYVVRRMDLPFRDVDWTTWDDLLDRVHNPEHEIVMALVGKYIDLPDAYLSVTEALRAGGFANKARVKIKWVTSDDCKTPAGARVQLGDVDAICIPGGFGERGVTGKVGAIQYARENGIPLLGLCLGLQCIVVEAARNLAGVADANSTEFDPATAHPVVSTMAEQLDIVAGEGDMGGTMRLGMYPAKLAEGSIVREVYDGKEYVEERHRHRYEVNNAYRAELEKKAGIVFSGTSPDGKLVEYVEYPRDVHPYLVATQAHPELRSRPTRPHPLFAGLVKAAVERKTSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YIDC_PSEA8
Sequence: MDIQRSILIVALAVVSYLLVLQWNKDYGQPELPAASASMNTTQGLPDTPSASGTSSDVPTAQSSAAGSEAADKPVAVSDKLIQVKTDVLDLAIDPRGGDIVQLGLLQYPRRLDRPDVPFPLFDNGRERTYLAQSGLTGADGPDASSAGRPLFHSAQSSYQLADGQNELVVDLSFSHDGVNYIKRFTFHRGLKADCSDKEKAQKKIECINENAYQVGVSYLIDNQSGKTWSGNLFAQLKRDGSADPSSTTATGVSTYLGAAVWTPDSPYKKISTKDMDKEQFKESVQGGWVAWLQHYFVTAWVPTKGEQHQVMTRKDGQGNYIVGFTGPTLSVPAGSKVETDLTLYAGPKLQKHLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSLIGNWGWSIIALTVLIKLAFFPLSAASYRSMARMRAVSPKMQAIKEQHGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLSLYWVLLESVEMRQAPWLGWITDLSVKDPFFILPIVMGGTMLIQQMLNPTPPDPMQAKVMKLMPIIFTFFFLWFPAGLVLYWVVNNCLSIAQQWYITRKIEAAAKTA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_SALTY
Sequence: MGLSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALVLRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_AQUAE
Sequence: MVEVEKKIKEGLTFDDVLLVPQYSEVLPHEVDVSTYLTKRIKLNIPIVSAAMDTVTEARLAIALAREGGIGIIHRNLPIKKQAEEVEKVKKSESGMIINPVTVKPDTRVKEALDIMAKYKISGVPVVDEERKLIGILTNRDLRFIKPEDYSKPVSEFMTKENLITAPEGITLDEAEEIFRKYKIEKLPIVDKEGKIKGLITIKDIVKRKKYPNACKDELGRLRVGAAVGTGEETLDRVAALVEAGVDVIVVDTAHGHSKRVLETVEKIKANFPEVDVIAGNVATAEGTKALIEAGADAVKVGVGPGSICTTRIVAGVGVPQLTAIMEAASAAREYDIPIIADGGIRYSGDIVKALAAGASAVMLGNLLAGTEEAPGETIYYQGRAYKVYRGMGSLGAMSSRLSSDRYGQEKMEKFVPEGIEGRVPYKGKLADVVYQLVGGLRSGMGYVGARNIKELQEKAKFVRITWAGYRESHVHDVQITREAPNYWVD
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: SP5G_STAAW
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: RL2_PYRAB
Sequence: MGKSLIQQRRGKGSPTFRSPSHRFRGAVKYIPLNYTQDKTLRGVVEEIMHDPGRTAPVARVRFENGMEKLIIAPEGLLVGQEIYIGPDAPIAIGNTLPLAKIPEGTYVYNIEGIPGDGGKYVRAGGTYALVVSREKDKVIVQLPSGELKAFNPNCRATIGVVAGGGRLEKPLVKAGKAYYKYKARNRFWPTPRGVKMNAVNHPFGGKEHHPGKPTTTSRRAPPGRKVGHIAARRTGRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL14_PARXL
Sequence: MIQTETRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVTVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNAKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CAV2_ATEAB
Sequence: MGLETEKADVQLFMDDDSYSHHSGVDYGDPEKFVDSGQDRDPHRLNSHLKVGFEDVIAEPMNMHSFDKVWICSHALFEISKYVIYKFLTVFLAIPLAFTAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWRSVTDVIIAPLCTSIGRICSSVSLQVSHD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27- phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.
Protein: YMDB_SHIDS
Sequence: MKTRIHVVQGDITKLAVDVIVNVTNPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQQGDE
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate.  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: TRMD_LEGPL
Sequence: MALHLGIITLLPEIIQGIHYGVTGRAIEQGLVKIDCWNPRDWSSRPYKQVDDKPYGGGPGMVIMYEPLHAAIKHARSEMKENCKTIYLSPQGKVVRQNDLKQIAAQKQSLLFVAGRYEGIDERIISHHVDEEWSLGDFVLSGGELAAMVFIDAIIRLIPGSLGHLGSAVQDSFMNGLLDCPHYTRPATINGLDVPDVLLGGNHKEIERWRRKQSLGKTWLKRPDLLEKVQLSETDKQLLAEFKCEHGDSC
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_BRASO
Sequence: MSAKDVKFGVEARDRMLRGVDILANAVKVTLGPKGRNVVLDKSFGAPRITKDGVTVAKEIELDDKFENMGAQMVREVASKSADAAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDLAVEAVVADLVKNSKKVTSNDEIAQVGTISANGDSEIGKFLADAMKKVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNADKMRVEMDDAYILINEKKLSSLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVNLSMLGRAKKVMIDKENTTIVNGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGILPGGGVALLRASEQLKGVRTKNEDQKTGVEIVRKALSAPARQIAINAGEDGSVIVGKILEKEQYAYGFDSQSGDYVNMVSKGIIDPTKVVRTAIQNAASVASLLITTEAMVAELPKKAAAGPAMPPGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_KLEP3
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIESVEKSCFQKGYTLILGNAWNDPEKQRAYLSMMAQKRVDGLLVMCSEYPDSVLSMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFQGGYIAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMQAMKEAHISVPENWIVQGDFEPESGYRAMQQILSQQHRPTAVFCGGDIMAMGAICAADEMGLRVPQDISLIGYDNVRNARYFSPALTTIHQPKDSLGEAAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFVDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: RBFA_NITEU
Sequence: MSRDFSRTVRVADQIQRELALLIQNEIMDPRVGMVTLTGVEVTRDYAYAKVFYTTLGGDENIQLVEEGLKHAAGFLRSQLAGKIRLRVVPQLQFVYDESVERGMKLSRLIDEAVGKA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_ECOL6
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NSP3_ROTBU
Sequence: MLKMESTQQMASSIINTSFEAAVVAATSTLELMGIQYDYNEIYTRVKSKFDYVMDDSGVKNNLLGKAATIDQALNGKFGSVMRNKNWMTDSRTVAKLDEDVNKLRMMLSSKGIDQKMRVLNACFSVKRIPGKSSSVIKCTRLMKDKIERGAVEVDDSFVEEKMEVDTVDWKSRYDQLERRFESLKQRVNEKYTTWVQKAKKVNENMYSLQNVISQQQNQIADLQNYCSKLEADLQNKVGSLVSSVEWYLKSMELPDEVKTDIEQQLNSIDTISPINAIDDLEILIRNLIHDYDRTFLMFKGLLRQCNYEYAYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: CYSA_YERPE
Sequence: MSIEINNISKYFGRTKVLNDITLDIPSGQMVALLGPSGSGKTTLLRIIAGLENQNAGRLSFHGTDVSRLHARDRRVGFVFQHYALFRHMTVFDNIAFGLTVLPRRERPNAAAIKQKVGQLLEMVQLGHLAERFPSQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVVSQGNIEQVGTPDEVWREPATRFVLEFLGEVNRLSGEIRGSQLFIGAHHWPLDLAPMHQGSVDLFLRPWEMEVSTQSSDRCPLPVQVLEVSPRGHFWQLTVQPIGWHQDPISVVLPEGNIDAPVRGNRYYVGGLNARLYSGNQLLQPIALAQSA
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TPPF_ARATH
Sequence: MDLNSNHKSSVLKDPSPSVNQSRLGVSSRFMMSQWKKPAKLDDVRSNGWLDAMISSSPPRKKLVKDFNVEVAPEDDFAQRAWMVKYPSAISSFAHIAAQAKKKKIAVFLDYDGTLSPIVDDPDRAIMSDAMRSAVKDVASYFPTAIISGRSRDKVYQLVGLTELYYAGSHGMDIMTSSDGPNCFKSTDQQGKEVNLFQPAREFIPVIDEVFRTLVEKMKDIKGAKVENHKFCASVHYRNVDEKDWPIIAQRVHDHLKQYPRLRLTHGRKVLEVRPVIDWNKGRAVEFLLESLGLSNKDDLLPIYIGDDTTDEDAFKVLRDGNRGFGILVSSIPKESNAFYSLRDPSEVKKFLKTLVKWAKLEKNSTGF
What is the function of this protein?
Participates in the regulation of trehalose metabolism.
What are the official names of this protein?
Probable trehalose-phosphate phosphatase F, AtTPPF, Trehalose 6-phosphate phosphatase, Trehalose-phosphate phosphatase 5.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: PDXA_PSET1
Sequence: MTLRIAITPGEPAGIGPDLLLKLAQQTWDAQLVAIADANMLKQRAKHLGLSIKLIEFDQHAAATPAPAGSLYLHQVDVAEPVELGVLNDANGQYVLDTLRIASEKNMDGTFAAVVTGPVHKGIINKAGISFSGHTEYFAQQSNTADVVMMLATQGLRVALVTTHIPLAYVSRAITEDRLIKVASILNHDLQTKFGIEKPRILVCGLNPHAGEDGHLGREEIDTIIPTLEILNNQGMNLIGPLPADTLFQDKYLNEADAVLAMYHDQGLPVLKYKGFGNSVNITLGLPFIRTSVDHGTALDLAGKGTADVGSFELAIREAIKLAQEKAQNQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_ATHGR
Sequence: MEQTYQYAWIIPFLPLPVPMLIGLGLLLFPTATKSLRRMWAFQSVLLLSIVMIFSMNLSIQQINSSSVYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGIMVLIYSDNYMSHDHGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAAKACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFQIFNNLISNNEVNFLFVTLCAVLLFAGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLMPLFIVIPHIMNFISLIGIITVFLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYCPKKSQNMVLMGGLTKHVPITKNSFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWSTAGLTAFYMCRIYLLTFEGHLNVHFQNYSGKRNTPLYSISLWGKEGSKISNKNFRLVTLLKMKKNGRPSFFSNKVYKMDENVRNLIQPFLSIPNFGNTKTSLYPYESDNTMLFPILILILFTLFVGFLGIPFNQDVDILSKWLTPSINLLHKNSNNSIDWYEFCKDAVFSVSIASFGIFIAFFLYKPVYSSFQNLDLINSFVKIGPKRIFSDKIKKAIYDWSYNRGYIDAFDGTFLTVGMRKLAEFTHFFDRRIIDGIPNGVGLMSFFVAEVIKSVGGGRISSYLFFYFSYVSIFLLIYYFLNY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIMP_FRATM
Sequence: MLLDDLYEIVEPITADLGYILWGIEVVGSGKLTIRIFIDHENGVSVDDCQIVSKEISAVFDVEDPVSGKYILEVSSPGMNRQIFNIIQAQALVGFNVKAVTLAPVGSQTKFKGVLERVEGNSVILNLEDGKEISFDFDELKKLRVSPDFS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_SALPK
Sequence: MNNILSEEVLNVTDFTTSRQLTLWKREDLQSSQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTSKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRAMEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H8A17_CYRHA
Sequence: MVNVKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 17, U3-TRTX-Hhn1a, Hainantoxin-VIII.17, HNTX-VIII.17, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.