PharMolix/UniProtQA huggingface dataset:
Protein: AKH_KARBO
Sequence: QVNFTPGW
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ELOA1_MOUSE
Sequence: MAAESALQVVEKLQARLAANPDPKKLLKYLKKLSILPITVDILVETGVGKTVNSFRKHEQVGNFARDLVAQWKKLVPVERNSEAEDQDFEKNNSRKRPRDALQREEELEGNYQESWKPSGSRSYSPEHRQKKHKKLSEPERPHKVAHSHEKRDERKRCHKVSPPYSSDPESSDYGHVQSPPPSSPHQMYTDLSRSPEEDQEPIISHQKPGKVHSNTFQDRLGVSHLGEQGKGAVSHHKQHRSSHKEKHPADAREDEKISAVSREKSHKASSKEESRRLLSGDSAKEKLPSSVVKKDKDREGSSLKKKFSPALDVASDNHFKKPKHKDSEKAKSDKNKQSVDGVDSGRGTGDPLPKAKEKVPNHLKAQEGKVRTNADGKSAGPLHPKAEETDVDDEFERPTMSFESYLSYDQPRKKKKKVVKTSSTALGEKGLKKKDSKSTSKNLNSAQKLPKVNENKSEKLQPAGAEPTRPRKVPTDVLPALPDIPLPAIHANYRPLPSLELIPSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRLLTNNIRSAHANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKVRIKPAPYTTGSSHVPASNSSSNFHSSPEELAYDGPSTSSAHLAPVASSSVSYDPRKPAVKKIAPMMAKTIKAFKNRFSRR
What is the function of this protein?
As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A.
What are the official names of this protein?
Elongin-A, EloA, Elongin 110 kDa subunit, RNA polymerase II transcription factor SIII subunit A1, SIII p110, Transcription elongation factor B polypeptide 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGA49_CANAL
Sequence: MNYITSLLLLSSNTFLHPTTTYLQSMNDSIVLVTSSVSTELTTLGYDPISTISGVNGTNNIDYIKLLNDTNSTFVQLDNSDTDIDDSSSNSEDVSSNDEQIALMNSSSDFSDESDEGNDSDDNGDEVENMENNQANESDTQNENDRVLNYDTSSSENENENENENENQLEQEHQHYYYKNRSKFYNHFLRYPEVVINNNDDRAELASTKNNLLVRSPKSNNRRLIGSSRKKTLKSKSKSKSSKLKHKSRKSHKRRPKLLKSKDVETNEITTVEVITLTITKVLARHDLAAIVTPIQQHQSGHLIIGYPLPIATKSRLHGYYKSSGVLKEVDANPTEEYDSGDGKENTQQNPIPEKMRLPTNDDPYSLKPTHHYDPSATMQNPHKQFTNRTGNFEIPTNVQDIDDITFPIDLSSSDSTSNLYSILPMNQTNLPDVNTLSLAPGTGSVPPRYSNHHSEFTVERPPRPSRTKKRPRIKAKKTMKVSTQISSAMSKSIHITRIGSTSSGIASGITNIVIPNSSSSIYDNYQDSSSDKQPVSLSMPTKTITMTTDTTSEPVTITEKLDKPKFPDIFTIIRSKLLSKKPQETKLHSPTSTDTKSSKLMSSSSSNNNKPEISKTTKEYNQTQESTSYNTTKAVPKTSVVSSTTSTKPNDQGNNILNSFIQFTETIHSRIRFPTADDNNNNAGNNYHRRFTGVVLPENRQFVFRSASQNLSFSVLGLIILLLLLPGLLIIIM
What are the official names of this protein?
Predicted GPI-anchored protein 49.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: TRPF_CHLCV
Sequence: MKVKICGVTHPEDAEYAALLGADYIGVIFAEKSKRKTSLSMAKSIADTTKRLGAEPVGVFVEQTTDQIIAICEQTGIKTIQLHSTFPLGALENLLRDYSIIYAISVRENGDVCHPQSLPPKVIPLYDTEKGGTGKQFNWKAFSLPKDTFWMLAGGLNPKNIEEAVATLHPNGVDVATGVEFPNKTRKDPDLLKAFILSAKKSGEKI
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL19_DEHMB
Sequence: MEETMNNQEAPETSEEETVAVENTKAEKVLPNFGPGDTIKVHARIKEGDKERIQMFQGVVLKVKQAADGGNFTVRRISYGVGVERTFPFLSPNVTKVEIMKKGRVRRARLFYLRKLSGKAARIKEVKQTPS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RSXB_SALG2
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: HEM11_HORVU
Sequence: MAGATSATAAAGAFAAAKARGPAAACPWLVAAGGRRRSGVVRCDAGGDAQAASKAASITALEQFKISADRYMKEKSSIAVIGLSVHTAPVEMREKLAVAEELWPRAISELTSLNHIEEAAVLSTCNRMEIYVVALSWNRGIREVVDWMSKKSGIPASELREHLFMLRDSDATRHLFEVSAGLDSLVLGEGQILAQVKQVVRNGQNSGGLGKNIDRMFKDAITAGKRVRCETNISAGAVSVSSAAVELAMMKLPKSECLSARMLLIGAGKMGKLVVKHLIAKGCKKVVVVNRSVERVDAIREEMKDIEIVYRPLTEMYEAAADADVVFTSTASESLLFTKEHAEVLPPISLAMGGVRLFVDISVPRNVGACLSEVEHARVYNVDDLKEVVEANKEDRVRKAMEAQTIITQELKRFEAWRDSLETVPTIKKLRSYADRIRASELEKCLQKIGEDNLNKKMRRSIEELSTGIVNKLLHGPLQHLRCDGSDSRTLDETLENMHALNRMFSLDTEKAVLEQKIKAKVEKTQS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 1, chloroplastic, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BC1_TGMVY
Sequence: MDSQLACPPNVFNYIESNRDEYQLSHDLTEIILQFPSTASQLSARLSRSCMKIDHCVIEFRQQVPINATGSVVVEIHDKRMTDNESLQASWTFPVRCNIDLHYFSSSFFSLKDPIPWKLYYKVCDSNVHQRTHFAKFKGKLKLSTAKHSVDIPFRAPTVKILSKQFTDKDVDFSHVGYGKWDRKMIRSASTSTIGLTGPIELRPGESWASRSTIGPSPSYAGSDQGDAMHPYKHLNRLGTTILDPGESASIIGAERTQSNITMSMVQLNEIVRATVQECINTNCTPSQPKTLQ
What is the function of this protein?
Movement protein involved in the cell-to-cell and systemic transport of viral genomic DNA.  Begomoviruses use 2 proteins to transport their DNA from cell to cell.  The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates further movement across the cell wall (By similarity).
What are the official names of this protein?
Movement protein BC1, Movement protein BL1.
What is the protein family that this protein belongs to?
Belongs to the begomovirus movement protein BC1 family.
What are the subcellular locations of this protein?
Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host microsome membrane; Peripheral membrane protein; Cytoplasmic side. Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found on ER-derived vesicles.
Protein: ATPI_CUSEX
Sequence: MDVLSCSINTLKGLYDISGVEVGQHFYWQIGDFLVHGQVLITSWVVIAILLGSATVAVRNPQTIPTGGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKILQLPHGELAAPTNDINTTVALALLTSAAYFYAGILKKGLGYFEKYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMLLGLFTSGIQALIFATLAAAYIGESMEGHL
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, plastid, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: RAB9A_MOUSE
Sequence: MAGKSSLFKIILLGDGGVGKSSLMNRYVTNKFDSQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKTDIKERQVSTEEAQAWCKDNGDYPYFETSAKDSTNVAAAFEEAVRRILATEDRSEHLIQTDTVNLHRKPKPNSSCC
What is the function of this protein?
Involved in the transport of proteins between the endosomes and the trans-Golgi network (By similarity).  Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (PubMed:26620560).
What are the official names of this protein?
Ras-related protein Rab-9A, Sid 99.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Melanosome. Note=Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: DEN4B_HUMAN
Sequence: MAEERPPRLVDYFVVAGLAGNGAPIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPPPELPPDLPPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKSAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB10.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
What are the official names of this protein?
DENN domain-containing protein 4B.
Protein: TTLL9_CAEEL
Sequence: MSSISNELSVTSSQNVISNSKEQRKKKILFKCALTNTISDVLTNREGWAQTQGDDWQFFWVTREWMTTCYDKHKFSEKQMICHFRNDFELTRKDFLIKNYKKARKAKEKSGIDVVSEFNFLPSSYVLPTEYHLFVEEFRKYPNDTIWIMKPVAGAQGKGIFLFRKLKHVQEWKKKDSSGSEALPYVVQCYVHNPYLVGGKKFDVRIYVLVTSFRPLNAWVHREGFARFSHSRYSTDSVDDAFVHLTNVAVAKTAADYDPERGLKWSLPKLFRFFKSVHGQSKLSKTMNDLTNVIIESLKSVQNLIIQDNHCFELYGYDILFDENLKPWLLEVNASPSLTASSQEDFELKYRILNHMIDVLDIEKKLIGNENEVGGFDLLIKNSKPVELCKVDFHTQPFFGTQFNLRLGDYVEATPMP
What is the function of this protein?
Polyglutamylase that forms polyglutamate side chains on tubulin (By similarity).  Acts when complexed with other proteins (Probable).  Appears to be dispensable for polar spindle formation in dividing embryonic cells, for cilia-dependent osmotic avoidance and for male mating behavior (PubMed:27635036).  Probably by regulating microtubule stability via the glutamylation of tubulin, regulates PLM axon developmental growth (PubMed:23000142).
What are the official names of this protein?
Probable tubulin polyglutamylase ttll-9, Tubulin--tyrosine ligase-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: NIKE_STAAC
Sequence: MIELKHVTFGYNKKQMVLQDINITIPDGENVGILGESGCGKSTLASLVLGLFKPVKGEIYLSDNAVLPIFQHPLTSFNPDWTIETSLKEALYYYRGLTDNTAQDQLLLQHLSTFELNAQLLTKLPSEVSGGQLQRFNVMRSLLAQPRVLICDEITSNLDVIAEQNVINILKAQTITNLNHFIVISHDLSVLQRLVNRIIVLKDGMIVDDFAIEELFNVDRHPYTKELVQAFSY
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import system ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NU3C_MICAN
Sequence: MFVLKGYEYFLGFLLACSLVPILSLTASKVLRPSGGGPERRTTYESGMEPIGGAWIQFNIRYYMFALVFVVFDVETVFLYPWAVAFNQLGLLAFVEALIFIAILVVALVYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RBL1A_RHOPS
Sequence: MLKSYQAGVREYRETYWDPHYTPKDSDILAVFKVIPQAGVPREEAAAAVCAESSTATWTTVWTDLLTDLDYYKGRAYAIEDVPGDDEAFYAFVAYPMGLFEEGSIVNVFTSLVGNVFGFKAVRALRLEDVRFPLWFVTTCDGPPHGIQVERDKLDKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFEFCQEAIEKAEQETGERKGHYLNVTAPNMEEIYRRAEFAKEIGSPIIMSDYLTIGWAAHSSLSRWCRANGMLLHVHRAMHGVIDRNPRHGINFRVLAKLLRLLGGDHLHSGTVVGKLEGDRAATLGWVDLMRERHVKEDRSRGLFFDQPWGHMAPVMPVASGGIHVWHMPALLAIFGDDAVFQFGGGTLGHPWGNAAGAAANRVALEACVRARNEGRDVEREGKDILTAAAQSSPELKVAMETWREIKFEFDVVDKLDAPHR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain 1, RuBisCO large subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RL16_BRASO
Sequence: MMQPKKTKFRKAHKGRIHGVASSGATLAFGQFGLKAMEPDRVTARQIEAARRALTRHMKRAGRVWIRVFPDLPVSKKPAEVRMGSGKGSPELWVARVKPGRVMFEIDGVSNQIAREALTLAAAKLPIKTRFVERIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYM_PECAS
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHVQADIWVRYQRMRGNQVHFICADDAHGTPIMLKAQQMGIAPEQMIAAMSQEHQQDFAGFNISYDNYHSTHSEENRELSGLIYGRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKAADQYGDNCEVCGATYSTTELIEPKSAVSGATPEMRESEHFFFDLPAFSDMLQAWTRSGALQEQVANKMQEWFDSGLQQWDITRDAPYFGFEVPDAPGKYFYVWLDAPIGYMGSFKNLCDKRGDLNFDDFWKKDSDADLYHFIGKDIVYFHSLFWPAMLEGSGFRKPTNLFVHGYVTVNGAKMSKSRGTFIKAGTYLQHLDADCLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFISKRFDGKLADKLADAELYKTFTDAGASIAEAYSSRESGRAIREIMALADIANRYVDEQAPWVVAKVEGRDADLQAICSMGINLFRVLMTYLKPVLPALTQRTEAFLNTELSWDAITTPLLSHQVNPFKALFNRIDLDKVSAMVDASKEDMVTAQNVVSGPLADNPVQDTINFDDFAKVDMRIALIKQAELVDGSDKLLRLTLDLGGETRQVFSGIREAYPDPAKLEGRLTVMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDSGAQPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BACP2
Sequence: MKVTKSDIVISAVKPEQYPSGGLPEIALAGRSNVGKSSFINSLINRKNLARTSSKPGKTQTLNFYIINDMLHFVDVPGYGFAKVSKTEREAWGRMIETYITMREELKAVVQIVDLRHKPSVDDVNMYEFLKYYGVPVIVIATKADKIPKGKWEKHAKVVKQTLDIAPSDELVLFSSETKKGKDEAWNAILAKINK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PDXK_BORA1
Sequence: MSSGQGYVASGRPLLFDVVSVQSQVVYGHVGNNVAAPALRAHGLHPGIVPTVLLSNTPHYPTLHGGALPLSWFEGYLQDLQARGALQALRAILVGYLGSAEQARVLGRWIARIREVHPQVLVIVDPVMGDDDHGLYVTEGLAEASRECLVPQAHGLTPNSFELGLLTGCEVGRVDQAVAAARRLLAQGLRWVVVTSAAQQDCPPGQVQLLAVTASQAHLLRHQRVDTAPKGTGDLFCAELTAHLLAGASLERAVEASSRYLVQALACTRLADSAELLMPSRDPAQAQAVQWIPLEN
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: RL13_POLNS
Sequence: MKTFSAKSHEVVHEWFVIDATDKVLGRVASEVALRLRGKHKPEYTPHVDTGDFIVVINSSKLRVTGTKGLNKIYYRHSGYPGGISSTNFDKMQDRFPGRALEKAVKGMLPKGPLGYAMIKKLKVYGDANHPHAAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RPOB_MAGMM
Sequence: MALTFTEKKRLRKNFGRISSIIDIPNLISVQKESFVRFLQTGTEFEKMKDTGLHGVFLSVFPIHDYAGTVSLEYVSYALGEPKYDVDECLQRGMTFSAPLKVAFRLVIWDENEETGTKTVREIKEQDVYLGEIPLMTNTGTFIINGTERVIVSQMHRSPGVFFDHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDPKDLLFARIDRRRKLPVTTLLRAMGMSSEQILERFYEIETFRKEGVVWQKRMVPERLMGNRLNYAIVHPESGEEIVKAKKRVTARHIKKFEELGMDWLPVSQEELIGSFVARNMSDVMGEVVIEAGAEITEEMVQYLEDGGIKEIDVLFIDGMSVGAYLRNTLALDKNSGQDEALIDIYRMMRPGEPPTVDAAKALFNNLFFNSDRYDLSTVGRLKMNSRLSLNTELHIRTLQHDDILGVVDILLKLKDGHGKVDDIDHLGNRRVRSVGELLENQVRIGLVRMERAIRERMSSAEADQLVPHDVMNSKPFSAVIREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGMTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLSTYARINEFGFIESPYRQVKEGTPIDQVDFLSAIDEENYIIAQANAKLGDEASEEDALIQCRHKLEFMVATPDRVNYQDVSPKQTVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKTDAPLVGTGIESVVARDSGVTITARRTGVVDEVDAARIVVKADEEPGSTEPGVDIYNLTKFSRSNQNTCINQVPLVKNGERVTAGDIIADGPSTQIGELALGRNVLVAFMPWNGYNFEDSILISERLVAEDVFTSIHIDEFEVMARDTKLGAEEITRDMPNVGEDALRNLDESGIIYVGAEVKPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVRDTSLRLPPGVAGTVVDVRVFSRRGLEKDDRAKLIDQDEIALLRKDMAAERRIIERDADERIRNLMNGKPVRSAPGLQPGDHISQSWLDKSPSSHLRDVVLDDDAITQQIEGIRHHVEKAADRLKKRFESKVEKLERGDDLPPGVLKMVKVYIAVKRKLQPGDKMAGRHGNKGVISKINPLEDMPYMANGTPVDIVLNPLGVPSRMNVGQILETHLGWAARGMGFKIEEALKQHRKGVADVLRRQFEEIYDNTRESAEIAALSDDQLVDMAKNLQYGVPTATPVFDGAIESDISSWLNKAGLPTSGQIQLIDGRTGEPFDRHVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKIYESIVKGDDTFEAGVPESFNVLVKELQALALDVTLQRDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PSTB_SYNE7
Sequence: MSPTAGENILLKAEALSVYYGNSLAVKDVYLEVPKNKIVAFIGPSGCGKSTILRCFNRMNDLINGCRVQGRITFHDQEINDGRVDAVELRSRIGMVFQKPNPFPKSIYENIAYGARINGYQGDMDELVEKSLRQAALWDEVKDKLKDSGLALSGGQQQRLCIARTVAVQPEVILMDEPCSALDPISTLAIEELMQTLKEQYTIIIVTHNMQQASRTSDYTAFFNARATEGGGKMGYLVEFDTTEKIFDSPDQEATADYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MED7_CRYNJ
Sequence: MSSLPQEAALPITNTLFPPPPPYFQAFTDEAIERYETLTGKSLFVNDEKGKTKGKEKKSDDRDMSVDIRIQDLTEEEQNEKLELEGKLEKPRADWVNEDGRWMCFGTMYTTEPIIPTAQSIGLPPFIDPAVEPQESLPPLLHSFLHTLLLLLDTLTMTARTPNELAAAGWASEGDQYIQHLTNLSANMMVASNQLRSAQSEATLVLLMEKELEERRKQTEKLRSKCKEIASGIRALKGL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RT12_PARTE
Sequence: MLSTLYQNDLKKKRNRRRNRSAALVCCPQKEGSVLKPRIVTPKKPNSARRPVAKAKLTNKKFVVAHIPGTGHNLRKHSTILVRGGGCRDLPGVRHTCIRGVSDFLGVRDKTKRRSIYGIKRPPEMAKRVRRKFRAIFGQ
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL13B_YEAST
Sequence: MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAAKIAPRPLDLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRDGKAPEAEQVLSAAATFPIAQPATDVEARAVQDNGESAFRTLRLARSEKKFRGIREKRAREKAEAEAEKKK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L13-B, Large ribosomal subunit protein eL13-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_KLEP3
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQFLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.