PharMolix/UniProtQA huggingface dataset:
Protein: IRAP_ECOBW
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOM22_RAT
Sequence: MAAAVAAAGAGEPLSPEELVPKAEAEKAEEDLEEDDDDELDETLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPPLPGKI
What is the function of this protein?
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (PubMed:19401463).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM22 homolog, rTOM22, Translocase of outer membrane 22 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom22 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: Y4EE_SINFN
Sequence: MITGKTISLPLSVIACLGAGASQAAACANQTDCLKSASAKVSQTLTPKVVPVFGDYPKLYIHDSAANEDYTVPDTTKQEFDFYTNKTSFNLPRRSSIETREIASISPAMGFTVLLVEKTRDNTVSNGGSTLSLLSSNSNDAYLSFALGAKPSSSGQKWSFAKSLLQGNKAQTAYWQKPWDMNLLGPTGDFSGTEWIYYTFTPDGKVRIDRFAPYTYFLAFTAYQWDEAVLDGGFPHFPFDTGTPTNRPQSVTFGSVGPWLIGAAGAPGQTPPTSEPIEALPGFEGATIFSAPLSMKEVIAYQNSLRGSYFLDVDMLPCNSGQYLSGRISTPCGTGSPGNPPPNINSVAQHRISTNTNR
What are the official names of this protein?
Uncharacterized lipoprotein y4eE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CCNB_DROME
Sequence: MVGTTLKMRGDENASENFKQVQLKKLTVPSMEATTKRAALGDLQNRGISRPIAAKDAAQKDSKDLKLTDALRNAKARVDSHWKKQPLGSTNGNGNGAVPPKVNEGGVSAFLRSNSVRNRVPTKTTVEPTKVTVKSSSSENVNEPTLKREDSNLSKKSLTKLRAALAKPVMGVSGIRREPVAVSRKEAETKKELPETKKDSLEVKKDATRMPLIRGNSAVTTTTSTMPTTMSLSSKRLAGIEDIDANDKENLVLVSEYVNDIYDYLYQVELEQPIHKDHLAGQKEVSHKMRAVLIDWINEVHLQFHLAAETFQLAVAIIDRYLQVVKDTKRTYLQLVGVTALFIATKYEELFPPAIGDFVFITDDTYTARQIRQMELQIFKAIDCNLSRPLPIHFLRRYSKAAGAEDEHHTMSKYFIELASVDYEMATYRPSEIAAASLFLSLHLLNGNHRAGTGFNDRHWTPTLTFYSRYSAAHLRPITRLIAKLARDAPQAKLKAIYNKYQGSKFQKIALRTELTGALMDSIVGQSQRK
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: 1A15_ORYSJ
Sequence: MIMSGFHIGIYTSICLYIPLPHLEPWIISSHTPKNLNLLDCLLYCSVASYTAIAYKFCTARLIQSERTRENIMGGKLLPAAAFAGSAPPLSQVATSAAHGEDSPYFAGWKAYDEDPYHAVDNPDGVIQMGLAENQVSFDLLEAYLRDHPEAAGWSTGGAGAGSFRDNALFQDYHGLKSFRKAMASFMGKIRGGKARFDPDHIVLTAGATAANELLTFILANPGDALLIPTPYYPGFDRDLRWRTGVNIVPVRCDSANGFQVTVAALQAAYDEAAAVGMRARAVLITNPSNPLGTTVRRKMLDDILDFVSRNDIHLISDEIYSGSVFAAPDLVSVAELVEARGGDGIAGRVHIVYSLSKDLGLPGFRVGVVYSYNDAVVTAARRMSSFTLVSSQTQKTLAAMLSDEAFAGEYIRTNRRRLRERHEHVVAGLARAGVPCLRGNAGLFVWMDMRRLLLGGGGVGGELRLWEKLLRQAKLNISPGSSCHCSEAGWFRVCFANMSLDTLDLALHRISRFMDTWNGTKQQASCQQQEQQ
What is the function of this protein?
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase 5, ACC synthase 5, OsACS5.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: RNH_XANCP
Sequence: MKSIEVHTDGSCLGNPGPGGWAALLRYNGREKELAGGEANSTNNRMELMAAIMALETLTEPCQILLHTDSQYVRQGITEWMPGWVRRGWKTSGGDPVKNRELWERLHAATQRHSIEWRWVKGHNGDPDNERVDVLARNQAIAQRGGLATS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_LEPBP
Sequence: MIQQETILQVADNSGVKKVMCVKVLGGSKKRYATLGDEIIVAVKEAQPAYGLRDGQGKKVHNKAVQRAVVVRTKKEVRRPDGTYIRFDDNAVAIIDDKGNPKGTRIFGPVARELRDKKYMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FMAH_DICNO
Sequence: MKSLQKGFTLIELMIVVAIIGILAAIAIPQYQNYIARSQVSRVMSETGQMRTAIETCLLDGKEGKDCFIGWTTSNLLAAAGGSTTNNATAADPGQGGLNITYALESTAENKIEATFGQNAAATLHGKKLTWTRSPEATWSCSTDVDEKFKPTGCKK
What is the function of this protein?
Major component of the type IV fimbriae that plays an essential role in twitching motility, natural transformation, and protease secretion.
What are the official names of this protein?
Type IV major fimbrial protein FimA, 265 antigen, Pilin, Serogroup H1, Two subunits pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: GVPF2_HALSA
Sequence: MSESHLYTYGIIDDNESLALNVDGVAGATRAYTVSYRSLSAVVSDIETTDPERTDAAVEAHNTVLQAVLEHDATRAVVPMSFGMAFKNARTLKGVLRGARRALRSTLTEIAGTVELGVKVLAPGDDTAVDTAAVRSDVTARLSALSVGETENDCFTDRLIINKSYLVEHDTRDAFDAAIDEIDAAHDDLTVRYTGPWPPYNFVDIHIGAEQAQQGGR
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpF 2.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: YQOC_CAEEL
Sequence: MAPTTVIADNNCNEESSNSFEMEIEAESAILEQIQNKMAKNLESAAYVPPTEEEQKAIDAKSVFIGNVDFNSTIEEVEEHFKGCGHIVRTTIPKDKFTKKQKNFAYIEFDDSSSIENALVMNGSLFRSRPIVVTAKRTNIPGMGHGVRGSSRGTFGRGRGAARGAPGRQQTVVVKYVYVNGPNRGGRGGRGRRFNPY
What are the official names of this protein?
Putative RNA-binding protein EEED8.12.
Protein: TALAN_HUMAN
Sequence: MSALGQITITVSRCWNTERNQTDKNPCLHGAYLQLRETVKNKSTHLKKPLMKQAPPWKDHLTFQPLHPAERKTQVWRWQSGNSSDLETTSSASPWPTGSNRDVVLNTLAESCCGLSELITAPPYAGVSIQGFSQIWVLFPFCGGTFHHNEKDVLGLQDFERESVSTSQSRNISLLTLGQLQNCVIGKLTIIDLLTEHLLGVRHGVICFPWGLPSSS
What is the function of this protein?
May play a role in uric acid excretion.
What are the official names of this protein?
Talanin.
Protein: MGSA_HAEI8
Sequence: MQTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSIQSLLSGPMGGDQQLGGLIAEKKIDMMIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINQSSADFLLTSVLFEQDVEIDVPDYEGYLKERLA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: LUPS_KALDA
Sequence: MWKLKIADGGSNPYIFTTNNFVGRQIWEFDPQATDPQQLAKVEAARLDFYHNRYKLKPNSDLLWRMQFLEEKAFTQTIPQVKVEDGEEVSYEAVTAALRRGVHLYSALQASDGHWPAENAGPMFFMPPMVMCLYITGHLNAIFTEEHRSETLRYIYYHQNEDGGWGFHIEGHSTMFGTVLNYICMRLLGEGPEGGQDNAVSRGRKWILDHGGATSIPSWGKTWLSIMGLCDWSGCNPMPPEFWLLPSYLPMHPGKMWCYCRMVYMPMSYLYGKRFTARITPLILQLREEIHIQPYDQIDWKKVRHVCCKEDMYYPHPLLQDLLWDTLYLTTEPLLTRWPLNKLIRKRALQTTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYLWIAEDGMKMQSFGSQHWDTAFSIQALLASNMAEEIGITLAKGHDFIKKSQVKDNPSGDFKGMYRHISKGAWTFSDQDHGWQVSDCTAEGLKCCLLFSMMQPEVVGESMAPESLYNSVNVLLSLQSQNGGLPAWEPAGAPEWLELLNPTEFFENIVIEHEYVECTSSAVQALVLFKKLYPLHRRKEVERFITNGAKYLEDIQMPDGSWYGNWGVCFTYGAWFALEGLSAAGKTYNNCAAVRKGVDFLLNIQLEDGGWGESYQSCPDKKYVPLEDNRSNLVQTSWALMGLIYAGQADRDPTPLHRAAQLLINSQLEDGDFPQQEITGVFQRNCMLHYAAYRNIFPLWALAEYRRQIQLHSEATKMV
What is the function of this protein?
Oxidosqualene cyclase that generates lupeol, a triterpenoid product.  Lupeol is probably required to coat the leaf exterior as a defense compound against pathogens or herbivores.
What are the official names of this protein?
Lupeol synthase, KdLUS.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: RSMG_PSECP
Sequence: MVDITAAELRAAEKIFGDRLDLAKRYVEHLATSGTERGLIGPREIPRLWSRHVLNCAVIESEIPQGSRVADVGSGAGLPGLCLAIARPDLELTLIEPLERRVIWLQEVVDDLGLDNVTVMRSRAELAVGHVEADVVTARAVSALTNLAGLTIPLLGGTGEVIAIKGRSAGEEIEKAAKAIRKLGGVETSVLTVGDNLLEEPTTVVRIVVNKPQKKS
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1178_METJA
Sequence: MIIMKVLMPSIYYPYIGGITLHVENLVKRLKDIEFHILTYDSYEENEYKNVIIHNVPHLKKFRGISYLINAYKIGKNIIESEGIDLIHSHYAFPQGCVGALLKNKLSIPHILTLHGSDALILKNSIKGRYFFKYATTNSDKIICVSKYIKNQLDENLKNRAIVIYNGVNKEILYNEGDYNFGLFVGAFVPQKGVDILIDAIKDIDFNFKLIGDGKLYKKIENFVVKNNLSHIELLGRKSFDEVASFMRKCSFLVVPSRSEGFGMVAVEGMACSKPVIATRVGGLGEIVIDGYNGLLAEKNNPNDLKEKILELINNEELRKTLGENGKEFSKKFSWEKCVMGVRKVYEELSD
What are the official names of this protein?
Uncharacterized glycosyltransferase MJ1178.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: RS5_SHEB5
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKIGYGYGKAREVPAAIQKAMEKARRNIVTVELNAGTLHHPVKGRHTGSLVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KAD_BORPD
Sequence: MRLILLGPPGAGKGTQAAFVTQHFAIPQISTGDMLRAAVKQGTPLGQEAKKVMDAGGLVSDEIIIGLVQDRLKQPDCANGYLFDGFPRTIPQADALKSAGVALDYVVEIEVPEDDIIERMSGRRVHPASGRSYHVRFNPPKQEGLDDVTGEPLVQRDDDREDTVRNRLAVYQKQTRPLVDYYASWAQAGDGKAPKYRKISGVGAVDDIKARLFQALAS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_MEASY
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAIGEAMAAWSEISDNPGQERATYKEEKAGGSGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDTETLGIPSRNLQASSTGLQCHYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSEGDNESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSETPIKKGTDARLASFGTEIASLLTGGATQCARKSPSEPSGPGAPAGNVPECVSNAALIQEWTPESGTTISPRSQNNKEGGDHYDDELFSDIQDIKTALAKIHEDNQKIISKLESLLLLKGEVESIKKQINKQNISISTLEGHLSSIMIAIPGLGKDPNDPTADVEINPDLKPIIGRDSGRALAEVLKKPVASRQLQGMTNGRTSSRGQLLKEFQLKPIGKKMSSAVGFVPDTGPVSRSVIRSIIKSSRIEEDRKRYLMTLLDDIKGANDLSKFHQMLMKIIMK
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus P protein family.
Protein: GLCT_STAAS
Sequence: MGEYIVTKTLNNNVVVCTNNDQEVILIGKGIGFNKKEGMALNDQTITIEKIYKLESEQQKAHYKSLVEIADDNVLQVIIDSLNFISNTAMNVDSKQLVVSLTDHIIFAYKRLKQNQVISNPFVMETMQLYSDAYHIAKQVIDQLNAALDVHFPEDEIGFIALHIASNTEDLSMHEMTLINNVIKKGIDIIESDLVTTVDKESLQYQRFIRHVQFLIRRLRRKEYIHAQDDFVSMIKNHYPICYNTAYKILTMIQKQFDVNISESEIIYLTLHIHHFEERINQS
What are the official names of this protein?
Protein GlcT.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.
Protein: RL35_SHEFN
Sequence: MPKMKTDKGVAKRFKKTANGFKRKQAHLRHILTKKSTKRKRHLRAKCLVAKSDVPAIARQLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CLCN5_RABIT
Sequence: MAMWQGAMDNRGFQQGSFSSFRSSSSDEDLMDIPGTAMDFSMRDDVPPLDREIEEDKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLFSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSENVTFEDTDKCPEWNSWSQLIINTDEGAFAYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHRFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVIEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGADLPDRPAGVGVYNAMWQLALALILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWTIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons.  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: HEM3_PSESM
Sequence: MSSREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDSPLSKIGGKGLFVKELETALLEDNADIAVHSMKDVPMDFPQGLGLFCICEREDPRDAFVSNTFESLDALPAGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYNAIILAAAGLIRLGFEDRITSAISVDDSLPAGGQGAVGIECRSVDAEIHALLAPLHHEDTAVRVIAERSLNKHLNGGCQVPIACYAVLEGDDVWLRGLVGDPSGRVLLHADARAPQTSAQALGVQVAEALLAQGAAEILKAVYGEANNE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: BG1_ORYSJ
Sequence: MERWAAPKVTAGSARRYVADQPSFSSTLLDAIYKSMDEQPGHGGGATGVEAVAAAAKKQHEAALHYGNYYKPSLAGSYRARAPGPHATTSSSSECSSYGGFSSSEAESSHHRRLRPIRTTVPGGAPGPAPEKKAKKPGASIRAKLRDLRKPASPGARLAGFLNSIFAGKRAPATPPSATAGAESACSTASSYSRSCLSKTPSTRGQAKRTVRFLDSDTESLASSTVVDRRRVPVEAVQQMLLQRMEMESDEDDDESSDASSDLFELENFAAIAPAGAAYRDELPVYETTRVALNRAIGHGYGHGRSARVV
What is the function of this protein?
Involved in auxin transport.  Positive regulator of the auxin signaling pathway involved in gravitropism, plant growth and grain development.
What are the official names of this protein?
Protein BIG GRAIN 1.
What is the protein family that this protein belongs to?
Belongs to the BIG GRAIN 1 (BG1) plant protein family.
Protein: CYB_MICOR
Sequence: MTIIRKKHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIMLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGILILLMASMILTLFFPDILGDPDNFTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAFMPLLHTSKQRALTFRPITQIMYWTLVADLLILTWIGGQPVEYPFITIGQTASIAYFAIILIFMPITGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CHEZ_ECOLI
Sequence: MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPIDLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIERQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF
What is the function of this protein?
Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
What are the official names of this protein?
Protein phosphatase CheZ, Chemotaxis protein CheZ.
What is the protein family that this protein belongs to?
Belongs to the CheZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with CheA chemoreceptor patches near the cell poles, which requires CheA(short).
Protein: EFP_RICCN
Sequence: MKISANSIRTGNILVYNNDLWVVSKTPEHTQPGKGGAYVQVEMKNLKTGTKRNERFSSANYLEKAELEQKDYQFLYFEGDDLVLMDTKHFDQINISKEMLEEKLSFLTENMIVKVEFYNDKPLNIELPPTVILEISETDPVIKGATATASYKSAILENGIKVKVPQYLEIGEKIVVKTDDMTYVERAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS3_RAT
Sequence: MNRFNGLCKVCSERRYRQITIRRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRVVPQIKPGPDGGVLRRASCKSTHDLLSPPNKREKNCTHGAPTRPEQRHSCHLVCDSSDGLLLGGWERYTEVGKRSGQHTLPALSRATTPTDPNYIILAPLNPGSQLLRPVYQEDAIPEEPGTTTKGKSYTGLGKKSRLMKTVQTMKGHSNYQDCSALRPHIPHSSYGTYVTLAPKVLVFPVFVQPLDLCNPARTLLLSEELLLYEGRNKTSQVTLFAYSDLLLFTKEEEPGRCDVLRNPLYLQSVKLQEGSSEDLKFCVLYLAEKAECLFTLEAHSQEQKKRVCWCLSENIAKQQQLAATPTERKMFETEADEKEMPLVEGKGPGAEERTPSKDPSPSQELPPGQELPPSKDPSPSQELPPGQELPPSKDPSPSQELPPGQELPSSKNPSPSQELPAGQDLPPRKESFSGQEAAPGPESPSSEDIATCQNPPQSPETSTSKDSPPGQGSSPTTEVPSCQGLPAGQESTSQDPLLSQEPPAIPESSASDQNVLPSQESPPSQGSLSEKALAEQTISPGELPAATAGEPSASRPNFVIPEVRLDSAYSQQDGAHGGSSGEDEDAEEGEEGEEGEEDEEDDTNDDNYGDRNEAKRSSLIETGQGAEGGLSLRVQNSLRRRTHSEGSLLQEARGPCFASDTTLHCSDGEGTTSTWAIPSPRTLKKELGRNGGSMHHLSLFFTGHRKMSGTDLADDVEASRKRKSKNIAKDMKNKLAIFRRRNESPGAQPAGKADKTTKSFKPTSEEALKWSESLEKLLLHKYGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQACKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLINQKKMSPPL
What is the function of this protein?
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form.  Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
What are the official names of this protein?
Regulator of G-protein signaling 3, RGS3, SRB-RGS.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
Protein: A1IB2_LOXHI
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAIGDVVKAYKKAGVSGHVWQSDGITNCLLRGLSRVKDAVANRDSGKGYINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVIADVMNEAAYKNKVRLATYEDSPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2bii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_HAEIE
Sequence: MATYTTSDFKPGLKFMQDGEPCVIVENEFVKPGKGQAFTRTRIRKLISGKVLDVNFKSGTSVEAADVMDLNLTYSYKDDAFWYFMHPETFEQYSADAKAVGDAEKWLLDQADCIVTLWNGAPITVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIRVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARM1_DROPS
Sequence: MSTPRPEEHQKFSAAAALCPLSNCQFSGVVISAIADEQKLEFTNKYKGSCTLLCSYDSQGIVLRIVLDADREHVLKEYMIAADTDAAQMGRRSYAVTLESDNLVLRFASDQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPNGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLIDIPLEFQILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQGSRNSSSMLNGGLGVNGIGDGSMDITHGLMHPH
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity).
What are the official names of this protein?
Histone-arginine methyltransferase CARMER.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.