PharMolix/UniProtQA huggingface dataset:
Protein: COKA1_MOUSE
Sequence: MSLQGSYQHFCLWMFLGTTLALGQGQVSSRLRLAVLPEDQLQMKWREAEGSGLGFLVQVTPMAGDLEQELILTTKTPKATVGGLNPSKSYTLQIFELTDSGPILLARREFVIEDLKSQSLGRGSRRLAGATLEPTSLPLRGPDSEKTSEPSIAFTLSRDLPILDHPQFQCTPPTPADIIFLVDGSWSIGHNHFQQVKDFLASIITQFAIGPDKVQVGLTQYSGDPQTEWDLNSFQTKEQVLAAVHHLRYKGGNTFTGLALTHVLEQNLKPAAGVRPEAAKVLILVTDGKSQDDVRTAARILKDQDIDVFVVGVKNVDEAELKLLASQPLDITVHNVLDFPQLDTLAPLLSRLICQKIQGRGPVKPAAGTRVLDPLPTPTRLILTHATSSSIHLSWTPALYPPLKYLIVWQPSRGGAPKEVVVEGPVSSMELGNLTSSTEYLVSVLPVYESGVGKSLQGRATTAPLPPPGPLTLAAVTPRTLHVTWPPSAGVTQYLVQYLLATSTGEEQKREVHVGQPEVLLDGLEPGQDYDVSVQSLRGPEASEVQSIRARTSALGPPRHLTFSDVRYNSTCVSWEAQRPVRLVKVSYISSDGSHSGQTQVPGNLTSATLGPLSSSTMYTVRVTCFYLGGGSSVLTGHVTTQKAPSPGQLSVMELPGDAVKLSWLATALSGVLVYQIKWMPLGEGKAREISVPGTLGTATLPGLMKHVEYEITILAYYRDGTRSDPVSLRYTPSAASRSPPSSLALSSETPNSLQVNWTPPSGHVLHYRLNYTLASGSGPEKSISVPGTRSHAVLRDLMSATKYRVLVSAVYRAGESMAVSATYRTAACPALHPDSSLSGFDLMVAFGLVAKEYASIRGVAMEPSALGVVPTFTLFKDAQLMRRVSDIYPATLPPEHTIVFLVRLLPETPREAFALWQMMAEDFQPILGVLLDAGRKSLTYFNHDSRAALQEVTFDLQDAKKIFFGSFHKVHIAVGHSKVRLYVDCRKVAERPIGDAGSPPTGGFITLGRLAKARGPRSSSATFQLQMLQIVCSDTWADKDRCCEIPALRDGETCPAFPSACAYSSETPGPPGPQGPPGLPGRNGPPGQQGHPGPKGEPGPPGQTGPEGPGGQQGSPGTQGRAVQGPMGPPGAKGEKGDQGLSGLQGLSGQQGIPGKTGLQGPKGMRGLEGPAGLPGPPGPRGFQGLAGARGTNGERGAPGAVGPTGLPGSKGERGEKGEPQSLATIFQLVSQACESAIRTHVLKLNSFLHENARPPMPFMAETAKLGRPRSIDPGLHNEALLPGDWGHILRPEDQGEPVTISHTSNPRLQEVQTPESLE
What is the function of this protein?
Probable collagen protein.
What are the official names of this protein?
Collagen alpha-1(XX) chain.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DNLJ_OCEIH
Sequence: MNKEQVSKKIESLIELLNQYGYEYYVLDNPTVPDAEYDQKLRELQQLEQDFPDLVMENSPTQRVGGAPLASFQKVTHNVPMLSLGNAFNEQDLRDFARRASNGTDQPISFVCELKIDGLAISLTYENGKFVRGATRGDGTIGEDITSNLKTIRSIPLSIKEQGTLEVRGEAYMPHKSFLALNELREKNEEEPFANPRNAAAGSLRQLDPKIAAKRNLDIFLYGVGEWENSDLTSHSEHLTRLKELGFKTNKEWKKCNTIDEVIEYVNYWTEHRNDLSYEIDGIVIKVDSLDQQEELGFTAKSPRWAIAYKFPAEEAMTTLRDIELSIGRTGVVTPTAILDPVRVAGTTVQRASLHNEDLIREQDIRIGDKVVIKKAGDIIPKVVRSVVEQRNGDEQEFHMPDECPACGNELVRLEEEVALRCINPNCPAQLMEGLIHFVSRNAMNIDGLGEKVIIQLFQENLVQTMADLYRLDKEELLQLERMGEKSVTNLLEAIEKSKENSLERLLFGLGIRFIGSKAAKTLAMEFETMENLQKATYEDVLAIDEIGDKMADSIVQYFAEEKVTELLSNLRELGVQMEYKGPRKSEQATDSVLSGKTVVLTGKMEKFSRKEAKEIIESLGGTVTGSVSKKTDIVIAGEDAGSKLDKAEKLGIDVWSEQQLEDVVGK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LIN54_CAEEL
Sequence: MNQGEIVYQDDDDYYDESEIYDNYEEGAEFIEVNGQLVPHNPNLQAQQNRPGTSSMIQQHNRSMEVNQGLVKDEPIDTSSHRVYVPPPRPVQRKLFQPGPSTPGSSQYTVRNLSNLSGSPSMYDRQPASLPRTVQPMGLEMGNSEQRKVYIDMKDHVSHIRLKTKKKVFAPGQRKPCNCTKSQCLKLYCDCFANGEFCRDCNCKDCHNNIEYDSQRSKAIRQSLERNPNAFKPKIGIARGGITDIERLHQKGCHCKKSGCLKNYCECYEAKVPCTDRCKCKGCQNTETYRMTRYKNSGGAVSNTNALMSLTNASSTATPDSGPGSVVTDEHGDDYEDMLLSHKPKVEMDPRRFPWYYMTDEVVEAATMCMVAQAEEALNYEKVQTEDEKLINMEKLVLREFGRCLEQMITNTTELTQDLDAAPTDDIPGPSTSTS
What is the function of this protein?
Synthetic multivulva class B (synMuvB) protein.  SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repress transcription.
What are the official names of this protein?
Protein lin-54, Abnormal cell lineage protein 54.
What is the protein family that this protein belongs to?
Belongs to the lin-54 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to condensed chromosomes during the diakinesis phase of meiosis.
Protein: MBTL_MYCSS
Sequence: MQTSNSESVSAALTEILRDDMNVDIRRVTRESRLIDDVGLDSVAFAVGMVAIEDRLGVALTEEDLLSCDTVGDLEAAIQAKVPSSPSGQ
What is the function of this protein?
Acyl carrier protein involved in the formation of acyl-S-ACP intermediates within the mycobactin biosynthesis process.
What are the official names of this protein?
Acyl carrier protein MbtL, ACP, Mycobactin synthase protein L.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CAMFF
Sequence: MHYVSISFTHKNTDIGVREKLSFSDNNRRREILRLIGANDSIAESMALSTCNRVEIFAYVLDTQSSIRHILNSISILTLVPFEALELRADIYEDQGAIHHLFAVASSLDSLVVGETQIAGQLKEAFKFAYDNEDCGVNISSAMHFAFKCAAEVRALTTISKNPVSVSSVAVAKAKEIYGNIGGMSAVVIGAGEMSRLAAQHLINAEVNVIIINRDEIKAQTLAKELGELASYASFDKLSEYINRYRLIFSATGAPNAIITNEIIEQKDFHRYFFDIAVPRDIDIEEDEYIHVYAVDDLEEIVRTNLALREEQASIAYSIVGKSTTSFFKWRLSEGSTPAIKALRLKAKDIACKEIEKAVKKGYLKCSDQDEASKLVHQVFKAFLHTPSVRLKEKNSDDILKALEYLFDIKIQKDENLEGNLK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RECR_BRUO2
Sequence: MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRAPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: CHED_GEOTN
Sequence: MRAIETVKVGIAEMKVVVAPTVIRTCGLGSCVGVVIYDSGKALAGMAHVMLPHSSMARGGVVNEAKYADTAVEALCKLVIAAGGRKAMLKAKLAGGAQMFSFSSTSGDMMRIGARNVEEVKRQLERLHIPVVAEDVGGHSGRTIEFNPQTGMLSIRTASQEIKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: SGT1_HUMAN
Sequence: MAAAAAGTATSQRFFQSFSDALIDEDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICEYHEKNYAAALETFTEGQKLDIETGFHRVGQAGLQLLTSSDPPALDSQSAGITGADANFSVWIKRCQEAQNGSESEVWTHQSKIKYDWYQTESQVVITLMIKNVQKNDVNVEFSEKELSALVKLPSGEDYNLKLELLHPIIPEQSTFKVLSTKIEIKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWDKLVGEIKEEEKNEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTNWSDVGKRKVEINPPDDMEWKKY
What is the function of this protein?
May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Protein SGT1 homolog, Protein 40-6-3, Sgt1, Suppressor of G2 allele of SKP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus upon heat shock, requiring S100A6.
Protein: CFI2A_SOYBN
Sequence: MAFPSVTSVTVENVTFPPTVKPPCSPNTFFLAGAGVRGLQIHHAFVKFTAICIYLQYDALSFLSVKWKTKSTHQLTESDQFFSDIVTGPFEKFMQVTMIKPLTGQQYSEKVAENCVAIWRSLGIYTDSEAEAIDKFLSVFKDLTFPPGSSILFTVSPNGSLTISFSGDETIPEVTSAVIENKLLSEAVLESMIGKNGVSPAAKQSLASRLSHLFKEPGVCDPQSHK
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
What are the official names of this protein?
Chalcone--flavanone isomerase 2-A, Chalcone isomerase 2-A.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: GSP1_CANAW
Sequence: MAQEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLGFHTNFGELKFDVWDTAGQEKFGGLRDGYYINGQCGIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGNPQLEFVASPALAPPEVQVDADLMQKYQQEMEQATALPLPDEDDADL
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein GSP1/Ran.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX13_YEAST
Sequence: MFRQCAKRYASSLPPNALKPAFGPPDKVAAQKFKESLMATEKHAKDTSNMWVKISVWVALPAIALTAVNTYFVEKEHAEHREHLKHVPDSEWPRDYEFMNIRSKPFFWGDGDKTLFWNPVVNRHIEHDD
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 13, mitochondrial, Cytochrome c oxidase polypeptide VIa.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATG12_CRYNJ
Sequence: MATTTPPLDRLSPAQAQPAVVVRFKSIGSAPIMKNNVFKATAGHKFQAVIMFLRQQLGMKKEDSLFTYINAAFAPAPDDTVGSLYKSFGTEGHLIVNYSNTQAWG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: TSAC_NEIM0
Sequence: MLFPRIIAASAQRKLSVYLKKGGLVAYPTESCYGLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQFEQLQPLLQMPSENLQDMLRKEWPAPKTFLLSAKSCVLPELRGKQRSKLAVRVPAHVGARRLCQALQTPLVSTSCNRAGKRACRTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGETGKRLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_COXB2
Sequence: MGPTASGKTDLAIALARKLPFEIISVDSAMVYRGLDIGTAKPNEEELQLTSHRLINICDPSFPYSAGQFYKDALSEIKTIEIRNRTPLLVGGTMLYFHILEQGFSDLPTADETVRKKIQEEAAQHGWAKIHERLNAIDPKSAARINPNDAQRIQRAFEVYETTGQPLSSYQSLKRFKALPYQFINLILAPENRSWLHQRIEKRFDQMLKNNFLEEVRQLYNRGDLNSDLPAIRTVGYRQVWKYLSGEYDYETMRHKAIAATRQLAKRQLTWLRRWPDAKWFNSEDKDLISQVVDYLKGIGM
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: GUAA_SALA4
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NDUBB_PANTR
Sequence: MAAGLFGLSARLLLAAAATRGLPAARVRWESSFSRTVVAPSAVAGKRPPEPTTQWQEDPEPEDENLYEKNPDSHGYDKDPVLDVWNMRLVFFFGVSIILVLGSTFVAYLPDYRMKEWSRREAERLVKYREANGLPIMESNCFDPSKIQLPEDE
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial, Complex I-ESSS, CI-ESSS, NADH-ubiquinone oxidoreductase ESSS subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB11 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=The interaction with BCAP31 mediates mitochondria localization.
Protein: URE3_STRT1
Sequence: MQLTMREQEKMMISLAAMIAQRRKDKGIKLNHPEAVALITDYVLEGAREGKTVAQLMDEARNLLTREDVMEGIAEMIPMIQVEATFTDSTKLVTVHDPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RET1_HUMAN
Sequence: MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVQ
What is the function of this protein?
Cytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518).  Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496).
What are the official names of this protein?
Retinol-binding protein 1, Cellular retinol-binding protein, CRBP, Cellular retinol-binding protein I, CRBP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Lipid droplet.
Protein: HSLU_BRASO
Sequence: MTDFSPREIVSELDRFIVGQADAKRAVSIALRNRWRRLQLDTGLREEVLPKNILMIGPTGVGKTEIARRLAKLAGAPFLKVEATKFTEVGYVGRDVEQIIRDLVEVAIHQVRERKRKDVAARAQLAAEERVLDALVGANSSAATRDSFRRKLRAGELNDKEIEIETQSSGGGMPMFEIPGMPGAQMGAISIGDIFGKLGGRTKTRRVTVEASHDILIAEESDKLLDSDQLVQEAINVVENNGIVFLDEIDKICVRENRHGGDVSREGVQRDLLPLIEGTTVSTKHGAVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELQALTRDDMRRILTEPEASLIKQYVALMKTEGVTLDITDDAIDALADVAVAVNSTVENIGARRLQTVMERVLDDISFTASDRTGETMRVDAAYVQQHIGDLAKNADLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_BURPS
Sequence: MTITPQEALQRTIEHREIFHDEMLHLMRLIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARRVEVEDNANFVDIVGTGGDGSHTFNISTATMFVAAAAGAKVAKHGNRGVSSKSGSADVLEALGVNIDLQPEQVAASIAETGMGFMFAPNHHPAMRNIAPVRRELGVRTIFNILGPLTNPADAPNQLMGVFHPDLVGIQVRVMQRLGAQHVLVVYGKDGMDEVSLGAATLVGELRDGEVREYEIHPEDFGMQMVSNRTLKVESADESRVMLLEALGNKPGVAREIVTLNAGTALYSADVAGSIADGIQLARDAIASGRAREKVDELVRFTQQFKR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: LGT_LACLM
Sequence: MNNLFPFLALDKIALQLGPLAIHWYAIFIVGGAALAVWLACKEAPKRNIKVDDIIDFVLFAFPLGIVGARLYYVIFQWSYYSQHPSQIIAIWDGGGAIYGSLIAGAIVLFVFSYYRMIHPLDLLDITIPGVFLAQAMGRWGNFVNQEAYGKIVSNLDWLPPFIRNQMFIEGHYRMPTFLFESIGTLSGFILVMVFRHRIKGLKRGDIFSSYLVWYGAVRFIVEGMRTDSLMLGPARVSQWLSVLLVILGIILFVYRRIKKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CC112_MACFA
Sequence: MEKDKHSHFYNQKSDFRIEHSMLEELENKLINSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGGWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQSWKTKKQQKREEIFKLNEKANNTPMLFHNKPEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKYASHLKEEEEKEKKRQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEKREKAEKAEKRKTAADGISRFQERDLHKLELKILDRQAKEDEKAQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGSGPLLHIPHRAIPTWRQGIQRRV
What are the official names of this protein?
Coiled-coil domain-containing protein 112.
Protein: E78C_DROME
Sequence: MDVYQIELEEQAQIRSKLLVETCVKHSSSEQQQLQVKQEDLIKDFTRDEEEQPSEEEAEEEDNEEDEEEEGEEEEEDEDEEALLPVVNFNANSDFNLHFFDTPEDSSTQGAYSEANSLESEQEEEKQTQQHQQQKQHHRDLEDCLSAIEADPLQLLHCDDFYRTSALAESVAASLSPQQQQQRQHTHQQQQQQQQQQQHPGQQQHQLNCTLSNGGGALYTISSVHQFGPASNHNTSSSSPSSSAAHSSPDSGCSSASSSGSSRSCGSSSASSSSSAVSSTISSGRSSNNSVVNPAATSSSVAHLNKEQQQQPLPTTQLQQQQQHQQQLQHPQQQQSFGLADSSSSNGSSNNNNGVSSKSFVPCKVCGDKASGYHYGVTSCEGCKGFFRRSIQKQIEYRCLRDGKCLVIRLNRNRCQYCRFKKCLSAGMSRDSVRYGRVPKRSRELNGAAASSAAAGAPASLNVDDSTSSTLHPSHLQQQQQQHLLQQQQQQQHQPQLQQHHQLQQQPHVSGVRVKTPSTPQTPQMCSIASSPSELGGCNSANNNNNNNNNSSSGNASGGSGVSVGVVVVGGHQQLVGGSMVGMAGMGTDAHQVGMCHDGLAGTANELTVYDVIMCVSQAHRLNCSYTEELTRELMRRPVTVPQNGIASTVAESLEFQKIWLWQQFSARVTPGVQRIVEFAKRVPGFCDFTQDDQLILIKLGFFEVWLTHVARLINEATLTLDDGAYLTRQQLEILYDSDFVNALLNFANTLNAYGLSDTEIGLFSAMVLLASDRAGLSEPKVIGRARELVAEALRVQILRSRAGSPQALQLMPALEAKIPELRSLGAKHFSHLDWLRMNWTKLRLPPLFAEIFDIPKADDEL
What is the function of this protein?
Induces the early late puff 78C which triggers puparium formation and development.
What are the official names of this protein?
Ecdysone-induced protein 78C, DR-78, Nuclear receptor subfamily 1 group E member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_PROMP
Sequence: MAAPVKKTGSKKSKKNVPNGVVHIQSTFNNTIVSITDTSGHVISWSSAGASGFKGARKGTPFAAQTAAEAAAKRALDQGMRQIKVLVRGPGSGRETAIRALQVAGLEITLIRDVTPLPHNGCRRPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: BIOB_PROMA
Sequence: MTLLNPNIPIRQEVKVRFDWSLEEIQEILEKPLFELLWEAQNVHRSVNPEYKVQLASLLSVKTGGCEEDCSYCSQSIYNSSDVTNQSDFDVKGVLEQAKAAKAAGADRFCMGWAWREIRDGKPFEAMLDMVRGVKELGLEACVTGGMLTNQQAARLAEVGLNAYNHNLDTSPEHYDKIISTRTYQDRLETLHRVRNAGITICCGGIIGMGETLKDRASLLRVLANMDPHPESVPINALVPVEGTPLENLSMVDPLEMVRMVATARILMPRSRVRLSAGREQLGKEAQILCLLAGADSIFYGDTLLTTSNPSIKADRELLASAGVSVNWDLYD
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CA109_HUMAN
Sequence: MTQDRPLLAVQEALKKCFPVVEEQQGLWQSALRDCQPLLSSLSNLAEQLQAAQNLRFEDVPALRAFPDLKERLRRKQLVAGDIVLDKLGERLAILLKVRDMVSSHVERVFQIYEQHADTVGIDAVLQPSAVSPSVADMLEWLQDIERHYRKSYLKRKYLLSSIQWGDLANIQALPKAWDRISKDEHQDLVQDILLNVSFFLEE
What is the function of this protein?
Involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024).  Acts together with SPATA5, SPATA5L1 and CINP (PubMed:35354024).
What are the official names of this protein?
Ribosome biogenesis protein C1orf109.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CITG2_SALTI
Sequence: MMPIPVNPTNASIQPQSLYDAWADLAWRAMLTEVNLSPKPGLVDRLNCGAHKDMALADFHRSAEAIRHWLPRFMEYGASCTRLPPESVLAGLRPLGMACEAAMFRATAGVNTHKGSIFSLGLLCAAIGRLYQLRQPIAAETLCATAADFCRGLTTRELRQNNLQLTAGQRLYQQLGLTGARGEAEAGYPLVIRHALPHYRALLAQGRDPELALLDTLLLLMSLNGDTNVASRGGADGLRWLQQQAAVLLHQGGIRTPDDLVYLHRFDQQCIERNLSPGGSADLLIVTWFLAQISQVNH
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 2, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: GFOD2_HUMAN
Sequence: MKMLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILLHQDVDLVCISIPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLVGNVLRFLPAFVRMKQLISEHYVGAVMICDARIYSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAGLPEQGPQDVPLLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWEAVEVLTEEPDTNQNLCEALQRNNL
What is the function of this protein?
Promotes matrix assembly.
What are the official names of this protein?
Glucose-fructose oxidoreductase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.