PharMolix/UniProtQA huggingface dataset:
Protein: KDSB_LEPCP
Sequence: MSTPGRSDQDAGAGTPPVDPAVSFTVLVPARLASTRLPRKALADLGGLPMVVRVAQRCALSGASAVVVATDSEEIRAACAAHGVRALMTRADHPTGSDRLAEACVQLGLDGRDIVVNVQGDEPLIEPGLIDACAGLLAQRSDCVMSTAAHALDDVEEYGNPNVVKVVTDAVGRALYFSRAPLPWWRDGYASGVLALPDPAPLRHIGIYGYSAGFLRRFPSLPESPLERIESLEQLRVLWHGERIAVHLSAVRPGPGIDTPEDLERVRRHFG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_RHOJR
Sequence: MAGTTQPSAIDDILAEHAGLEQQLADPALHNDPSAARKAGKRFAELAPIMATYAKLKSAQDDLDAARELAADDSSFAAEVPELEAQVLELDKALTDLLAPRDPHDGDDVVLEVKSGEGGEESALFASDLARMYVRYAERHGWRVEILDATVSDLGGYKDATLSIKSKGDVRDGVWARLKFEGGVHRVQRVPVTESQGRVHTSAAGVLIYPEPEEVEEVQIDETDLRIDVYRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKARAMQVLAARLQAAAEEAADAEASAGRQSQVRTVDRSERIRTYNFPENRITDHRIGFKSHNLDAVLDGELDALLDALGKSDREARLAAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_STRP4
Sequence: MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLMF_BACFN
Sequence: MAERNELHKRNRHNGQYDFSRLTEEYPPLKKFIVLNAYGTTSIDFFNPRAVKALNKALLISYYGIRYWDIPKNYLCPPIPGRADYIHYIADLIQPDISDESTGLKTAVPNTRQYRCLDIGVGANCIYPIIGQTEYGWTFVGSDIDPVSIDNARKIVTCNPALAHKIELRLQRDSRKIFEGIIAPNEYFDVTLCNPPFHSSKEEAEDGTLRKLSSLKGKKVTKAQLNFGGNANELWCEGGEFRFLLTMIEESRNYRKNCGWFTSLVSKEKNLGKLTAKLKSTDIAEHRIIEMHQGTKTSRILAWRF
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP3_STAAB
Sequence: MKYLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPLRRLWISSVTKKAIQQSFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYYTLSLTVKGFDFQLESNQRYTNKETLEQIVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYKDQARPLISKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKGFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
Putative DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: RL21_STAAT
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DHMA_CAUVN
Sequence: MDVLRTPDERFEGLADWSFAPHYTEVTDADGTALRIHHVDEGPKDQRPILLMHGEPSWAYLYRKVIAELVAKGHRVVAPDLVGFGRSDKPAKRTDYTYERHVAWMSAWLEQNDLKDIVLFCQDWGGLIGLRLVAAFPERFSAVVVSNTGLPIGVGKSEGFEAWLNFSQNTPELPVGFILNGGTARDLSDAERSAYDAPFPDESYKEGARIFPALVPITPEHASVEENKAAWAVLETFDKPFVTAFSDADPITRGGEAMFLARVPGTKNVAHTTLKGGHFVQEDSPVEIAALLDGLVAGLPQA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: DAPB_VIBCM
Sequence: MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPASTLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTAIGMGEAIAHAMGNQLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFANGAVKAAIWLAEQPAGFYTMTDVLGLNDL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT2_BOMMO
Sequence: MCDDDAGALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNCPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
What is the function of this protein?
Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin, muscle-type A2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MYH2_CANLF
Sequence: MSSDQEMAIFGEAAPYLRKSEKERIEAQNRPFDAKTSVFVAEPKESFVKGTVQSREGGKVTVKTEAGATLTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELIATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEFVTKGQTVEQVTNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSANFQKPKVVKGKAEAHFSLIHYAGVVDYNITGWLDKNKDPLNETVVGLYQKSSMKTLAYLFSGAQTAEAEASGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEMSNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQVSELKSKEEEQQRLINDLTTQRGRLQTESGEFSRQLDEKEALVSQLSRGKLAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKEARSLGTELFKMKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQTMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE
What is the function of this protein?
Muscle contraction.  Required for cytoskeleton organization (By similarity).
What are the official names of this protein?
Myosin-2, Myosin heavy chain 2, Myosin heavy chain 2a, MyHC-2a, Myosin heavy chain, skeletal muscle, adult 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: ATP6_PSEA6
Sequence: MAGSAGEQTISGYIQHHLTNASVGEGFWTFHVDTLAWSVVLGLVFILSFRAVAKKASAGVPGKWQACVELIVEFVDDTVKSTYHGKSALIAPLALTIFVWVLLMNLMDLIPVDFLPTAAALIAGESMDVIAAGQSHTYMKVVPTTDVNMTFALSLGVFALMIFYSVKIKGFGGFMKELYAHPFNTPWLYWFNFILELVSLIAKPLSLSLRLFGNLYAGELIFILIAGTLGVWQLPIHFLWAAFHLLVIPLQAFIFMMLTIVYLSLASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATA_HELPH
Sequence: MITLKQALSLSQDELETLKNEIDAKVRASDLNAYIKAPSLNGASAKGVPILIKDNISVKGWEVTCSSKILEGYVAPYHASVIENLHQNSMAGFGLSNMDEFAMGSTTESSCYGITKNPRDKNRVPGGSSGGSAAAVAGGLAVAALGSDTGGSIRQPASYCGCVGLKPTYGRVSRYGLIAYCSSFDQIGPITQNVEDASILFDAISGHDNKDSTSANLKPTQTFKNLNRDKRFKIAILRDHIKDASNEVQLAYENTLKALKEMGHEIVEKKMLDSHYQISIYYIISMAEASSNLARFDGVRYGRRAQNIKDLKELYLKSRSEGFGDEVKRRIMLGNFVLSSGYYDAYYLKAQQMRLIIKEQYNKIFEEVDLIFTPVAPTSAHLFNYHASPLEMYLSDIYTIGANLSGLPALSLPVAKDPLGLPIGMQFIAKAFDEQSLLDVSYALEQELDLKLD
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SCG2_PIG
Sequence: MAEAKTHWLGASLSLILLIFLLATAEAASFQRNQLLQKEPDLRLENVQRFASPEMIRALEYIEKLRQQAHKEESSPDYNPYQGVSVPLQQKENSDLPESSRDSLSEDEWMKILLEALRQAENEPQSSLKENKPYTLNSEKNFPMDMPDDYETQQWPERKLEHMRFPPMYEENSRDNPFKRTNEIVEEQYTPQSLATLESVFQELGKLTGPNNQKRERVDEEQKLYTDDEDDIYKANNIAYEDVVGGEDWNPVEEKIESQTQEEVRDSKENIEKNEQINDEMKRSGQMGLQDEDLRKEGKDQLSEDVSKVIAYLKRLVNAVGSGKSQNGQNGERANRLFEKPLDSQSIYQLIELSRNLQIPPEDLIDMLKTGEKPNASVEPEQELEIPVDLDDISEVDLDHPDLFQNKMLSKNGYSKTPGRAVSEALPDGLSVEDILNLLGMENAANQKPPYFPNQYNREKILPRLPYGPGRAKANQLPKAVWMPDVENRQMAYDNLNDKDQELGEYLARMLVKYPEIMNSNQVKRVPSQGSSEDDLQEENQIEQAIKERLNQHSSQETDKLALVSKRLPVATPKSDDAPNRQYLDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM
What is the function of this protein?
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
What are the official names of this protein?
Secretogranin-2, Secretogranin II, SgII.
What is the protein family that this protein belongs to?
Belongs to the chromogranin/secretogranin protein family.
What are the subcellular locations of this protein?
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Protein: CCD66_PONAB
Sequence: MNLGDGLKLETELLDGKTKLILSPYEHKSKISVKMGNKAKIAKCPLRTKTGHILKSTQDTCIGSEKLLQKKTVGSETSQAKGEKNGMTFSSTKDLCKQCIDKDCLHIQKEISPATPNMQKTRNTVNTSLVGKQKPHKKHITAENMKSNLVCLTQEQLQQILMTVNQGNRSLSLTENGKEAKSQYSLHLNSISNQPKDENIMGLFKKTEMVSSVPAENKSVLNEHQETSKQCEQKIAIENEWKPADIFSTLGERERDRSLLEAKKAQWRKELDEQVALKKKEKEVSEKWNDPWKKSESDKIIWEKHQILDQSRETVLLEHAFSAVKQELQRKWIEELNKQIEDDRQRKIEEKIIYSKGEEHDRWAMHFDSLKSYPGSQSQLSSRSTHKQPEYFCVSPDTQELADVSSVCTPTTGSQVEPSEEEHIAKPIKDVVMANSKKTNFLRSMTALLDPAQIEERDRRRQKQLEHQKAITAQVEEKCRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEIMTLKTNELFQTMQRAQELAQRLKQEQRIRELAQKGHDTSRLIKNLGVDTIQIEYNASNISNSRHDSDEVSGKMNTYMNSTTSPKKDTGVQTDDLNIGIFTNAESHCGSLMERDITNCSSPEISAELIGQFSTKKNKQELTQDKGASLEKENNRCNDQCNQFTRIDKQTKHMKKYPKRPDWNINKPPKRYIPASEKYPKQLQKQREEKEVRRQMELLHLVEKNNPGHLSQNRGISPEIFHSSHQETESKFRWHLVKKEEEPLNIHSFSKERSPSSPVPAVKNRTQQTQNTLHLPLKNSSYERENLISGGNQTELSSGISESSHFIPYVRTNEIYYLDPDAPLSGPSTQDPQYQNSQDCGQERQLFDSDCVRDPLLNPNMVKNRDRQQAILKGLSELRQGLLQKQKELESSLLPLAENQEENFGSSF
What is the function of this protein?
Microtubule-binding protein required for ciliogenesis.  May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (By similarity).  Plays a role in retina morphogenesis and/or homeostasis (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 66.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Note=Restricted to the centrosomes and the spindle microtubules during mitosis. Enriched in the inner segment of the photoreceptor.
Protein: NRAM1_ORYSJ
Sequence: MGVTKAEAVAGDGGKVVDDIEALADLRKEPAWKRFLSHIGPGFMVCLAYLDPGNMETDLQAGANHKYELLWVILIGLIFALIIQSLSANLGVVTGRHLAELCKTEYPVWVKTCLWLLAELAVIASDIPEVIGTGFAFNLLFHIPVWTGVLIAGSSTLLLLGLQRYGVRKLEVVVALLVFVMAGCFFVEMSIVKPPVNEVLQGLFIPRLSGPGATGDSIALLGALVMPHNLFLHSALVLSRNTPASAKGMKDVCRFFLFESGIALFVALLVNIAIISVSGTVCNATNLSPEDAVKCSDLTLDSSSFLLRNVLGKSSATVYGVALLASGQSSTITGTYAGQYVMQGFLDIKMKQWLRNLMTRSIAIVPSLIVSIIGGSSGAGRLIVIASMILSFELPFALIPLLKFSSSSNKMGENKNSIYIVGFSWVLGFVIIGINIYFLSTKLVGWILHNALPTFANVLIGIVLFPLMLLYVVAVIYLTFRKDTVKFVSRRELQAGDDTEKAQVATCVADEHSKEPPV
What is the function of this protein?
Probable metal transporter that may participate in the control of iron homeostasis.
What are the official names of this protein?
Metal transporter Nramp1, OsNramp1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAGE_HELPY
Sequence: MFVASKQADEQKKLVIEQEVQKRQFKKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQAYEPVLIVAIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAANSYLANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTVKKKIVIDETNRDYSLIFSNDFMRAYNEKQKRESFYDISFYLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLSKYHPIRLKEYTKDGVIYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSAIEISEYAPKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTSRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSLVLFADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGNQENNAWGNSVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFVHNFPANVSKDKQKLTMVYMDKDYGAYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKTNATMEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSNTLAAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNKATDRLDFSKTIIGVDGSSFLDNNDVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIREQCPTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKIIQNHSIIDKYQALRQMYQQIKEY
What is the function of this protein?
ATPase component of the type IV secretion system Cag (Cag-T4SS) (PubMed:26565397).  Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable).  Required for CagA translocation and induction of IL-8 in host gastric epithelial cells (PubMed:26565397, PubMed:8825091, PubMed:8962108).  Plays a key role in Cag-T4SS pilus biogenesis, especially in the localization and stabilization of the pilus-associated components CagI, CagL and the surface protein CagH (PubMed:26565397).  Is also critical for assembly of the entire cytoplasmic portion of the Cag inner membrane complex (IMC) (PubMed:31088930).
What are the official names of this protein?
Type IV secretion system protein CagE, CAG pathogenicity island protein 23, Protein PicB.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNZ_STRP1
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ATPE_BUCAP
Sequence: MDFYLDIVSVEKRIFSGLVDRIQVSGSEGEMGIYPGHTQLLSIIKPGVIYIFHKNKTEECLYISGGILEVQPSVVSILADVAIRGIDLDRKRVVKAKKQAEEYFKKETTNVKKDDVLLEISKAIAKLRVLEIMDKFKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RECR_STAAC
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVQFAKALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKGLYHVLHGSISPMDGIGPEDINIPSLIERLKNDEVSELILAMNPNLEGESTAMYISRLVKPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: CWP35_TOBAC
Sequence: TPHYXRFTWT
What are the official names of this protein?
50 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: LEG12_HUMAN
Sequence: MSQPSGGRAPGTRIYSWSCPTVMSPGEKLDPIPDSFILQPPVFHPVVPYVTTIFGGLHAGKMVMLQGVVPLDAHRFQVDFQCGCSLCPRPDIAFHFNPRFHTTKPHVICNTLHGGRWQREARWPHLALRRGSSFLILFLFGNEEVKVSVNGQHFLHFRYRLPLSHVDTLGIFGDILVEAVGFLNINPFVEGSREYPAGHPFLLMSPRLEVPCSHALPQGLSPGQVIIVRGLVLQEPKHFTVSLRDQAAHAPVTLRASFADRTLAWISRWGQKKLISAPFLFYPQRFFEVLLLFQEGGLKLALNGQGLGATSMNQQALEQLRELRISGSVQLYCVHS
What is the function of this protein?
Binds lactose.  May participate in the apoptosis of adipocytes.
What are the official names of this protein?
Galectin-12, Gal-12, Galectin-related inhibitor of proliferation.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPK1_STRGR
Sequence: IRSGRDADAYEPDRDGDELPQGRFLDRERSWLAFNERVLELAEDPATPILERANFLAIFASNLDEFFMVRVAGLKRRIATGVATRSASGLQPREVLDLIWTRSRELMARHAACYQQDIAPDLSDEGIQLIRWPDLTEKEQARLFTFFRQRVFPVLTPLAVDPAHPFPYISGLSLNLAVVVRNPVSGHRHFARVKVPPLLTRFLEASPQRYVPIEDIIAAHLEELFPGMEVLAHHMFRVTRNEDLEVEEDDAENLLQALEKELMRRRFGPPVRLEVEESIDPYVLDLLVRELKVSDAEVYPLPGPLELTGLFAIASLDRPELKFPKFIAGTHRDLAEVESASAPDIFAALRERDVLLHHPYDSFSTSVQAFLEQAAGDPDVLAIKQTLYRTSGDSPIVDALIDAAESGKQVLVLVEIKARFDEQANIKWARKLEEAGCHVVYGLVGLKTHCKLSLVVRQEGDTLRRYSHVGTGNYHPKTARLYEDLGLLTGDPQVGADLSDLFNRLSGYSRRETYRRLLVAPKSLRDGLIARINKEIAHHRAGRPAYVRFKVNSMVDEAIIDACCRAAQAGVPVDIWVRGICAIRPASRLSENIRVRSILGRFLEHSRVFSFGNGGEPEVWFGSADMMHRNLDRRIEALVRVTDPAHRAALSRLLETGMADTTASWHLGPDGNWTRHATDADGQPLRHVQEMLIEARRRRRATP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: TAG2R_AGEOR
Sequence: MRSIISLILISAMVFSMIAPVPEEERLQLSEDERGGCLPHNRFCNALTGPRCCSRLRCKELSIWDSICLG
What is the function of this protein?
Insect active toxin causing rapid but reversible paralysis in crickets.  No activity shown in mammals.  Does not show effect on mammalian voltage-gated calcium channels (By similarity).
What are the official names of this protein?
U2-agatoxin-Ao1r, U2-AGTX-Ao1r, Agel_17.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_SHIFL
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.