PharMolix/UniProtQA huggingface dataset:
Protein: PGAM5_DROVI
Sequence: MRKFTAFACGTGAGLAAYYLQKLRDPQLAVHNSWTNSDRPISECALWDSNWDFRDPKSLVRPQKNDLPQEQNRYNSDLEKHVAKSARHIILIRHGEYLDVGDSDDTHHLTDRGRLQAKYTGQRLRELGIKWDKVIASNMVRAQETADIILNQIDYDKAKLKHCSYLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFHRALPEQEKESYTLIVGHGNVIRYFVCRALQFPAEAWLRISINHASITWLTISPSGNVSIKYLGDTGFMPAKYLTHRIPRDAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: AN_GAHVM
Sequence: MELGTKFPLSKSCKDESRKRKRGITIDCDSQILVGDEQSNSTKTKPYDEICENIVPNYTFGNYILQKIDPNDCRHSLHPLYHRLFYIADVIKQGISEGSLLENKYSYILETEHILLDESRINNLSPSIHASRWCKMVESLTRLQANSELWHIFRQCLLTASSVKWSPNGTINTAGLITNDLPSRGQTESILFGTRNESLAKSLIAALCVSQSSVRTIDNSDKKNEFDNTTTGILDIEKYSCGLMIDIRTGMLGASLDMVMCNRNRHGILAPCLTDNNIETYEIKCRFKYAFCPEMRSELSQCYERLMATKTVQWFRRFLYTIDCPCVDYFRPDNYPRAKEALITSDDDWKVGHSAYHAAQSRIKCNEFEMHHLTLNKNMSSRVWLFGEPDLQTNSIYPLLWNTGERVLSIPIFANPRHQNFKQIFLQSYVASGYFGNRKIVPFLATFIGRHRRQTELGRCFSLFVDDTEASEVVYEITPEQAIPVILIITPVIIDNTFYVGIEESGYRAFGELVDHLWAKQCRI
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: SGF29_YEAST
Sequence: MDGYWDVVVSSLQDIYNANEVIPFDDELQTKKLNFLNMSKDQLQLHLNTFQEHMENVNRVHRILDNVRSNLSLMLNQSREEKSEENTEDAEEGEGTRMALSQGKKAVGKVGRSYWTSEYNPNAPILVGSEVAYKPRRGSADGEWIQCEVLKVVADGTRFEVRDPEPDELGNSGKVYKCNRKELLLIPPGFPTKNYPPGTKVLARYPETTTFYPAIVIGTKRDGTCRLRFDGEEEVDKETEVTRRLVLPSPTALANLARK
What is the function of this protein?
Chromatin reader component of the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK (PubMed:10026213, PubMed:15647753, PubMed:21685874, PubMed:24307402).  In the SAGA complex, SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (PubMed:21685874).  SGF29 is also required for heterochromatin boundary formation function (PubMed:24307402).  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes At the promoters, SAGA is required for recruitment of the basal transcription machinery (PubMed:10026213).  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8) (PubMed:10026213).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs) (PubMed:10026213).  SLIK is proposed to have partly overlapping functions with SAGA (PubMed:15647753).  It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus (PubMed:15647753).
What are the official names of this protein?
SAGA-associated factor 29, 29 kDa SAGA-associated factor, SAGA histone acetyltransferase complex 29 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SGF29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELO_BACHK
Sequence: MTKNNEAGWNLDHSYTTLPQSFYTEIPPTPVSSPELVKLNHSLAISLGFNPEELKKEAEIAIFAGNALPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQITPSGKRFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLQSLADYTIKRHYPEIEAHENRYTALLQEVIKKQASLIAKWQLVGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEALKIAQDEISKFSVQYENNWFLGMKKKLGLFSKEEQDHSLIEQLLKMMEKYKADYTNTFRSLTLNTIENTALFESPEFKEWYKLWQSRLEKQEESKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNGDYSVMEKLLEALANPYAYSTDQEEYCVLPTPTNRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SYT_BIFLS
Sequence: MAQATISITVNGEAKEVEATTTGVELFAEDKNIIAVKINGENRDLYTPLADGDTVEPITLDSEDGLAIMRHSATHVMAQAVQEVYPNAKLGVGPVIKDGFYYDFQVDKPFTPEDLKDIEKRIQRIIKSSQSFRRRSVTEEEALKEEADQPFKIELIEDKEAHLDPAAATEISEKELSFYDNVDRDGNVVWKDLCRGPHLPNTRYIKAFKIERSAAAYWRGSEKNPTMQRIYGTAWATKDDLKAYQTRLEEAAKRDHRKLGAEMDLFSFPDEIGPGLAVFHPKGAAVINAMEDYSREMHRKHHYSFVQTPHITKGGLYETSGHLHWYKDGMYPAMHLDEEYDADGNVTKPGFDYYLKPMNCPMHNLIFKSRQRSYRELPLRLFEFGTVYRYEKSGEVHGLTRVRGLTQDDSHIYCTREQMKDELTSLLTFVLNLLKDFGLSDFYLELSTKDPDKYVGSDEIWEEATRTLREVAEASHLDLVADPGGAAFYGPKISVQARDAIGRTWQVSTIQLDFNLPERFQLEYIAKDGTHQRPVMIHRALFGSIERFFAVLLEHYAGAFPAWLAPVQVLGVPVADEFAPHLAGFVKSLEDEMVRCEIDYSDDRFGKKIRNASKSKVPFILIVGEEDMNNNAVSFRFRDGSQLNGVPVDKAREQILAVIAKRVQVNSADDFNAAVAE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBXL5_XENTR
Sequence: MAPFPDEVDLFTGPHWRMKQLVGRYCEKLSNTNFSSNTDFLALLQSLYETFKEFKMHEQIENEYIIGLLQQRSQTVFNVHSDNKLSEMLVLFEKGMKNNEYEQLNYAQQLKERLEAFTSDFLPHMKEEEEVFQPMLMEYFTYDELKDIKKKVIAQHCSQKDTAELLRGFSLWNKAEELQKVFKYSVDEKIERDSKNRKSSASICNLPPEVMLNIFSYLNPQDLCRCSQVNTKWAQLARTGSLWRHLYPVLWARGDWYSGPPTHLDNEPDEDWISRRKDESRAYQEWDEDADIDESEETGEDDPSISVAQREKELLNSLVHYILPYIGHSVKTLVLAYSSATSNKVIRQILEYCPNMEHLDLTQTDISDSAFNGWCFGACQTLRHIDLSGCEKITDSALEKLSVALGMPLAHKKRLLKCYRNNRTVKDIRNQMRCGSLAQITGESGIYSDYSSSQIWILNSGNLGDIEDAADWKFRTTDGLGVLEMTPNLTCFSNGCCSRAVPGRWTNVIRQEHCKAAPLNYCGHTLCGNTLRTIQALPGSNIGTKTLQSEIRDICPGSAKLDQQVARVLQFLSLSGCHQITDHGLRVLTIGGGLPNLEHLNLSGCLNVTGSGLQDLVSACPSLNDEHFYYCDNISGPHAATASGCQNLQCGFRACCRSGE
What is the function of this protein?
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of ireb2/irp2.  Upon high iron and oxygen level, it specifically recognizes and binds ireb2/irp2, promoting its ubiquitination and degradation by the proteasome (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 5, F-box and leucine-rich repeat protein 5.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: UNG_LACAC
Sequence: MAKELIGNDWDQILNPIFTSDKYHELHNFLKKEYSTRQIYPDMYHIFTAFKLTPFNKTKVVILGQDPYHNPGQANGMSFSVMPGAQLPPSLRNIYKELYDDVGAIPVNHGYLKKWADQGVLLLNAVLTVPYGHANGHQGKGWEDVTDAAIKALSKRGKVVFILWGRFAQNKIPLIDQSKNFIIKSSHPSPFSADRGFFGSRPFSRCNTALINFGETPIDWQLPEKVSKSDLI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAA60_XENTR
Sequence: MSEEERPAALADTILRFLCHDDIDTVKELCADWFPIEYPDSWYRDITSNKKFFSLAATYNGQIVGMIVAEIKGRTKVHKEDGDILASSFSGDTQVAYILSLGVVKEFRKQGIGSLLLESLKSHISSTAQDHCKALYLHVLTTNSNAIRFYENRHFHQHHYLPYYYSIRGVLQDAYTYVLYLNGGHPPWTVMDYLQHLGSALAGFSPCTLPQRIYRQAHTLLRSLLPWSSISAKSGIEYSRTM
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol.  Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met.  Required for normal chromosomal segregation during anaphase.  May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences.
What are the official names of this protein?
N-alpha-acetyltransferase 60, Histone acetyltransferase type B protein 4, HAT4, N-acetyltransferase 15, N-alpha-acetyltransferase F, NatF.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA60 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably forms a intramembrane hairpin-like structure in the membrane.
Protein: YN59_SCHPO
Sequence: MSDREEKLAAAKQRLLEVKKKKRQAKSKNSVAEDNVDRESNDGNNQVNEPTGNDNTQVVENTEDISASNVVSAEGAEASTGDASTQSPETSENVVKNSVDESVAEKPEKEDLAVIESEDKAAKPDGEIKKNVETEVTSRSTSSQEKDELEKQVKTLHDLNEQKDKKIKELKERINDLTYDYETLKANADDSEGKQTLVSKREAALEEFQSKLLIRENEINKRELKMNGKEDDLKKREKDLENRLLKVEEHEKSLNERATKLSEANENFNNRFKEFEEREKSAIKQNKEQSSEGSKTANQTHEQKELINSLEKKVSDIALEKQLLEEAVERYKLAMVEFAECQRRLKELEAMHFEQPGSVTEKLFPDPTNFEVIDNVSIDLTLTGFPGAHGIPFSV
What are the official names of this protein?
Uncharacterized protein C713.09.
Protein: LACB_STRPG
Sequence: MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPIFGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNANVIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLETHHANQEDPDFFTEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: TPM4_RAT
Sequence: MAGLNSLEAVKRKIQALQQQADDAEDRAQGLQRELDGERERREKAEGDAAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKSSDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells (PubMed:7568216).  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (By similarity).  Smooth muscle contraction is regulated by interaction with caldesmon (By similarity).  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity).  Binds calcium (By similarity).
What are the official names of this protein?
Tropomyosin alpha-4 chain, Tropomyosin-4, TM-4.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers (PubMed:7568216).
Protein: YDBI_SCHPO
Sequence: MSDTMVKNQAEEDEIVKSLNNVLKIVVTARKCLDDMKPIELPSELVESPLSMLKDVATLIHQYTTKLSVAAKPPITRDALEKYANDMATTITPLIAAVQVFNAEKYGEIIQNRLKMYAERVLFGIEALLRSVSPKPLGYISEDWKTRGRLIDTGILWESCEKIEKLGSEGIVGYMLEEWDNFVSMLEDARSDLEDYKEGDDSNWDDFGSESEDDSKEAHSEEVFRSEEQIQLANSLLQKLNACKILFLSIKKRRIKNEYPNTFLGELFNAAKQTSDSIDDIVAQIQEDDENFENELDNFHRSARNLCKICISSAQEDSFTPWFSKWLENWEIVSQK
What are the official names of this protein?
Uncharacterized protein C22E12.18.
Protein: RS5_STRPN
Sequence: MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGRVGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGSGVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISVSDLA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CLCA_KLEP7
Sequence: MKAETPSFEAHQFVRVRRGDAVRRLIQRDKTPLAVLFMAAVVGTLAGLVGVAFEKSVNWVQNQRIGALAQVADHWYLVWPLAFILSALLAMVGYFLVRRFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFVGGMGTLGAGMVLGREGPMVQLGGNIGRMVLDVFRMRSPEARHTLLATGAASGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAAIIEVGKLSNAPVNTLWLYLVLGMLFGCFGPLFNFLVLRTQDLFQRIHGGNIKKWVLIGGLIGGLCGLLGLMQPSAVGGGFNLIPIAAAGNFSVGLLLFIFIARVVTTLICFSSGAPGGIFAPMLALGTLLGTAFGMAAIPLFPAYHLDAGTFAIAGMGALLAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILQRTLAKQEAEQAAKAQQAPRENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VQ17_ARATH
Sequence: MEIEATTVQKRRSLPTIAMHKQSRTLTKSKPKIRIIHIFAPEIIKTDVANFREIVQNLTGKQDHHHHDLPHQKGLKRNPRSRRSHDHHEVHDMNKSHGFCINSDEEEEGMVSMTWNGNGDESSGGFLNGLGDLDGFIQELGEFPYLPFTIDPAVASSSHLHGNVFAEPHHYA
What is the function of this protein?
May function as positive regulator of plant growth.
What are the official names of this protein?
VQ motif-containing protein 17, AtVQ17.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANMK_BRUME
Sequence: MPDLKRAIGLMSGTSMDGIDIALLATDGENWIERRASASMDYSDGFRARLKAGLVDARAIKDRAERPGLLRQLEHDLTLLHAVAVHDFLHEQGLQPHEIDVIGFHGQTVLHRSNESLTVQIGDGALLARETGIPVVYDMRAEDMRHGGQGAPLIPAYHAALAANLPLGLKGPVVFVNIGGISNLTYVGEDGALIAYDSGPGNMLIDQWMELHGHGRFDPGGATAMSGSVDRNTAHRYLEHEFFKGNHRRSLDRGDFAIPAKGELNLADGARTLAFVSAAAILKSASHLPARPRTYVVSGGGRKNGALMDELTALAERQGAHVIDADNAGFDGDAMEAEAWAYLAVRSLCGLPLTYPSTTGCDKPVSGGVPVRP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RL14_RHOPT
Sequence: MIQMQTNLDVADNSGARRVMCIKVIGGSKRRYATVGDVIVVSIKEAIPRGKVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLINNQSEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KHSE_BRUO2
Sequence: MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVEQGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYNRTKGAALLRGYTSVRPLSEAEADALPVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRGMRFHRQIESAAEYGLEMQEVAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: DGT6_DROME
Sequence: MDRTIIAPWKAEEKEQSEKLHRKLQGLALVHPLPDELRKLIAWDMFLKPNQVAFVHVMHYLFRLLDPAEFKRRFFWPITDKKSEANFRSSTVEYLKHLNEKHQLHWANIKSYLVVMPGGMRFINFLLEFVGFVIQELIKQREKSLGLEAGTPNVSAKVMARQNAVMKEYASSYVVNLEENTALLRDKTQKIRRLMADLSADMGVPEEQLADDGFLDEFEATAALGVERVITQPTERKFDLEASLCGLKEAIDLFQVKQAENNQSKEAVEKALRGMRVLFDCDAVTEGDFYDPLGASKMDALLNGFNRISGTIAEQLDANDHYNESNAFVTTDLQALRVELSQSEVQLNNLLKKLNEPSKKDKGSANASGSARVQTLQPATPRFESVISSKFVSTPPIRIDMGGGGGRNAPVRLALQDDFNGKQFDALSNSLLAPAPPRSARKLKALDQSTGIDLNGTLNRSKINDPMQMLRTIHKNTSKVKAAPQANLSSLGSKWKQMQASFGFDEAPVPGAAVISPQTSPTDPSDPFTPLSGSECTRIERIPRTSENNTSLIAKSAAVIKVLEVSRNVLNLSTSPSGRLDALVPHTESHQQDVAPRLQLNDRTINDSLQLDPDFNIENDKNAFNVSHKFDFDQIGGEDDLQNISDSVLKDIIF
What is the function of this protein?
As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220).  The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918).  dgt6 is required for kinetochore fiber formation, mediating nucleation and/or initial stabilization of chromosome-induced microtubules (PubMed:19836241).
What are the official names of this protein?
Augmin complex subunit dgt6, Dim gamma-tubulin 6.
What is the protein family that this protein belongs to?
Belongs to the HAUS6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=During mitosis, localizes at aster centers in prophase cells (PubMed:19836241). In prometaphase and metaphase, associates with the entire spindle (PubMed:19836241). During early anaphase, primarily detected on the kinetochore fibers undergoing anaphase shortening (PubMed:19836241). In late anaphase and telophase, becomes enriched at the central spindle but is excluded from its middle region (PubMed:19836241). In interphase cells, displays a uniform distribution (PubMed:19836241). Enriched at spindle poles during meiosis in oocytes (PubMed:23785300). During male meiosis, localizes to kinetochores in a microtubule-independent manner but does not concentrate on spindle microtubules (PubMed:24829288).
Protein: RNAS1_BUBBU
Sequence: KETAAAKFQRQHMDSSTSSASSSNYCNQMMKSRNMTSDRCKPVNTFVHESLADVQAVCSQENVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHYDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPL_SALPK
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTAA_BACVZ
Sequence: MNKALKALGVLTTFVMLVVLIGGALVTKTGSGLGCGRQWPLCHGRFFPELNAASIIEWSHRLASGVSIVLVLSLAFWAWRKVTPVFRETTFLAIMSIIFLFLQALLGALAVVFGSNALVMALHFGISLISFASVLILTLLIFEADKSDKKLVKPLRIGRKMQFHMIGLSIYTYIVVYTGAYVRHTKSSLACPDVPLCSRLNHGLPSHFQEWVQMGHRTAALLLFVWILVAFAHAVRSYKDQKQILGGWIAALAFVVLQALSGIMVVYSEMATGFALAHSLFIAGLFGVLCYFLLLIARFRYESKQRNI
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GNAQ_DROME
Sequence: MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPYLNAIKTLWDDAGIQECYDRRREYQLTDSAKYYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKQDHAAAKQFVLKKYLACNPDPERQCYSHFTTATDTENIKLVFCAVKDTIMQNALKEFNLG
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Could be the transducin analog, an amplifier and one of the transducers of a visual impulse that performs the coupling between opsin and cGMP-phosphodiesterase.  Could mediate a subset of olfactory and gustatory responses.
What are the official names of this protein?
G protein alpha q subunit, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q, dGQalpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: APAH_XANC5
Sequence: MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEEQRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRTLGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQPGWSPGLSGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGVHAIDTGAVWGGKLTALQLDSEELRVVQVPGREVTGPAPVARAPRRPRERQGRQRSRGNRGNAGNAAAGPKPSVDTPQD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: SYFA_BRUME
Sequence: MSDLEQLERQILEDIAAAVDEQGIEAVRVAALGKKGTVSEKLKTLGGMSPEERQMQGPAINGLKNRVTEALSERRTELRKAAVAARLEREKVDVTLPVRESAASRGRIHPISQVIDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFNPDEKGERKLLRTHTSPVQVHTMEKFAAMRDKEGRDEPIRIVIPGKTYRMDSDATHSPMFHQVEGLVVDKSANVANMKWVLEEFCKAFFEVPSVKMRMRPSFFPFTEPSVEVDIQCDRSGPHVKFGEGNDWLEILGCGMVHPNVLRMSGYDPEVYQGFAWGMGIGRIAMLKYGMPDLRAFFDADVRWIEHYGFRPLDIPTLFGGLSA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_MYCLE
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYASIGDVIVGTVKDAIPGGNVKRGDVVKAVVVRTAKECRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SNPF_RHOPR
Sequence: NNRSPQLRLRF
What is the function of this protein?
Neuropeptide.
What are the official names of this protein?
Short neuropeptide F, Rhopr-SNF.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.