PharMolix/UniProtQA huggingface dataset:
Protein: RS3_XYLFT
Sequence: MGHKVHPIGIRLGISADWNSKWYANKAEFARYLAADLKVRQVLRKKMSQAGISKILIERPSNTACVSMHVARPGVVIGKRGEDIEMLRKQVSDIMGVPVHINVIEVRKPELDAQLVAESVAQQLERRIMFRRAMKRSVSNAIRLGALGIKISVAGRLNGAEIARSEWYREGRVPLQTLRADIGYGFSEAYTNYGVTGVKVLMYHGDIFSFSSVSQEKQDDGSRGDRNADRSSRRSREVR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL2_KLEP7
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVSPWGLQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LIN7B_MOUSE
Sequence: MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHHSYTSLESRG
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (PubMed:10846156).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.  May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface.
What are the official names of this protein?
Protein lin-7 homolog B, Lin-7B, Mammalian lin-seven protein 2, MALS-2, Vertebrate lin-7 homolog 2, Veli-2.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: SCX25_CENTE
Sequence: MKVLILIIASVLLIGVECKDGYPKNSEGCKISCVIGNTFCDTECKMLKASSGYCWTLGLACYCEGLPENVEVWDSATNKCGGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Beta-toxin Ct25.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_BACLD
Sequence: MGAVFLSGRSGSGKTTFILNEIREKLRDEPLGKPIIFLVPDQMTFLMEYELSKTPDLGGTIRAQVYSFSRLAWRVLQHTGGMNRPFLTGTGIQMLLRRLIEEHKGEFKVYQNASDKSGFTEQVERMLTEFKRHCLPPQSIRDMMEGTGKSEYEDERILSDKLHDLYILYSKLEENLENQYVQSEDYLTLLAEQIPYAEEIRNAAVYVDGFHQFTPQEMSVLEQLMVHAEEITFSLTADKPFTANSPNDLHLFRMTGKAYYDLYQKAKELGLDPSEVRLEETKRHRHHPELQHLERYFDERPAKPYPGQTESLRIMQASNRRTEIEGIAREIHSLIRQGRFRLRDIAVIARNVEDYKDTIKEVFKDCELPFFIDGKESMQNHPLIELIRSTLDIIKGNWRYEAVFRCVKTELLFPEGQPKERLREQIDQLENYCIAYGIKGDRWTSKDPFVYRRYASLDEDFAKTDKEIETENMLNELKGWIVPPIHRLQKRLKKAETVREMAEAVYLYLEEADVPMKLEQERRLAEEGGRIAESRQHEQVWDAVIQLLDEFVEMMGTERISFALFQQMIETGLESLKFALIPPALDQVFIGNMDLSRMYGTKCTFLIGVNDGILPARPADDGVLSDEDREWLKRNGAQLAATGREQLLDENFLIYMTLSSPSEKLYVSYPIADSEGKTLLPSTVVKRLNELFPDSEEKMLIHEPEQLDDEAQLEFLVNKGIALSHLAGQLGIWTRQYAISDVWWSTYNFLMNEPDRIFSQNILSSLFFRNKVENLNRHVSRDLYGEHIQGSVSRMETFKACPFSHFASHGLKLKERQFFKLEAPDIGQLFHSALKLISDRLHELKLDWRDLTKAQCETLSSDAVERLAPKLQKEILLSSNRHHYVKQKLQKIIARVSGILSEHAKASGFAPVGIELGFGGKGPLPPMRFTLKNGCTMELVGRIDRVDKAESSKGLLLRIVDYKSSDKGLDLAEVYYGLALQMLTYLDLSITHSTDWLGMKASPAGVLYFHVHDPMIQASVPLGLDEIEKEIFKKFKMKGLLLGDQEAVKLMDTTLEQGRSNIISAGLKKDGSLRSDSDVVAEEDFHVLRRHIRRTFQQAGEEITDGKVSIEPYKLKDRTPCTYCSYRSFCQFDESLEENEYRILKPEKDSVILERLKKEDEADGDF
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: BTBD7_HUMAN
Sequence: MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAAAAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQSVSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPALSRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQKNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSSEAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL
What is the function of this protein?
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression.  Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion.  This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing protein 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGR_ECO57
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT35_YEAST
Sequence: MSYGLTGTSSKLRGTSSIFSWTQVRHFSRRRIAYPFYPFKKLGRQHPKKHDTNLKTAMRQFLGPKNYKGEYVMNKYFTVPTNHVPNYIKPDLERGQSLEHPVTKKPLQLRYDGTLGPPPVENKRLQNIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEEITVEGLSAQQVSQKYGLKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMDETLYRMFPVFDSDASFKRENLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLELEPAVETLRNLSTVGEHSSGHQQSTNKNTKVIYGELVEGERSQYKFTNAKVGKVGYRYGSGNRDNKKDRRIGFNKLGQMVYI
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein S35, mitochondrial, Mitochondrial small ribosomal subunit protein mS45.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS45 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: AZOR5_PSEF5
Sequence: MKLLHIDSSILGDNSASRQLSHSVVEAWKAAHPATVVTYRDLANDAISHFSAATLVAAGTAAELRDAAQKHEAQLSAQALAEFKAADTVVVAAPMYNFTIPTQLKAWIDRIAVAGETFRYTEAGPQGLCGGKKVIVVSTSGGLHVGQATGVAHEDYLKVLFGFFGITDVEFVRAHGLAYGEEVRSKAMSDAQAQISQQLFAAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 5, Azo-dye reductase 5, FMN-dependent NADH-azo compound oxidoreductase 5, FMN-dependent NADH-azoreductase 5.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RL19E_PYRAB
Sequence: MKTLKMQRRVAAELLKCGENRIWIDPERVDDVASAITREDIRRLIKEGVIKKKPVKGQSRYRARIRHEQKKKGRHRGPGSRKGKKTARMGKKELWIKTIRALRKELRKLKEQKKIDRRTYRMLYIRAKGGQFKSKHQLYMFLEEHNLLKKR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: Y2044_ARATH
Sequence: MATETNKELFVGGFAKILKEQRQVDVRLKAGDSGDEGASTSAHKLVLSARSEVFKKMLESDEIKASAQLETITLCEMKHEELEAFIEFIYSDGSMLSAKEKQHVRSLYIAGDKYEIPHLRDLCRIELISSLKSSNALDILELAQIPFDKALHDSAFFFFFFFFFG
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Putative BTB/POZ domain-containing protein At2g40440.
Protein: MUTS_METBU
Sequence: MIKLTPAMKQYYDAKKQHSDALIFFRMGDFYESFGEDAKIIAKELEITLTTRGKDIEGEKMPLAGIPYHALDNYLPRLIKKGYKVAICEQLEDPKKAKGIIKRGVVRVVTPGTAIDTSMFTDPSNNYLMSISGGDGDYGVSFLDVSTGEFLTTQFADKSPYDRIASEAARMRPSECIISRTMFSDERLVERLKELNVLVQGFKDEAFDVDSSRKLLERHFNVSTLEGMGCAGLPYATSSAGAALDYALTTQMRELGHVSELSTYSDSEFMMLDSITLRNLEIVKNVRGEGNDTSILKVLDDTNTPMGGRLLQKWLLKPLINVDSIDHRLDALECLANDTMLRFDVRSHLSFVKDIERLIGRVVYGNSNARDLIALKRSLGSVPQIVESMGDDPGCEMLINIRDGLLGFEQLENIVKLIDDAIVDEPPVSVREGGMIRSGYNEKLDELKGMSTGGKTWIASFQQKERDRTGIKSLKVGYNRVFGYYIEITKSNIAQIPDDYIRKQTMRNAERFYTPELKEWEDVILSADEKITALENELFTEITSRIASHASDLQRIAVLIGQLDCTASLAEVAVNNNFVRPNITSDCKILIREGRHPVVEKTVRGGFVPNDTEMDCVDEQFLLITGPNMAGKSTYMRQVSLIVIMAQAGSFVPASHASIGIVDRVFTRVGAFDDLASGQSTFMVEMVELANILNNATPKSLVLLDEIGRGTSTYDGYSIAKAVVEYIHNKGRVGVRSLFATHYHQLTNISSSLKRVKNYHIAVKEDGDDLVFLRKIVPGATDKSYGIHVARLAGVPHKVTQRAKEVLQDIEDESVISKESDSKRGRKKKSAQYTQLMLFDPEGSSAPVAEPDPVVEELKELDVNSMTPIEALNKLSELQKKAGKGGK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CHO2_ARTBC
Sequence: MARLSGVERPDDSGLRERKAKAVEEPVKQPVEGADGAAAAAQAKKKTIGRTPDGTDILVLSIIGLHIVLLYLLPSFLRIPIFAVLFLSWRAAYNIGIGWLLHMQSNHSTMVLWARQTKIFVNPATGDNPHPQLYSFIKRELETKIPEDYSFEDAPIEYNTWLVFRRVVDLILMCDFTSYCLFAIACGSRPAEENFLVLILRWVVGLGLVLFNLWVKLDAHRVVKDFAWYWGDFFYLVDQELTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISILAHAAQFAFLVLVENPHIEKTYNAPPPRKRTIESHAGLAGEEKSSRRPSESSEMVPPPSPVALPSSTHNLVGVKNLDLHRITDSSIILIQVLFFALTMLTPSTPIYQFFFVLNAAIWRLWYSVGIGYILNCQSHRREWTRHFVKFGETKEEAWNQWKGTYHLSMTLCYASFIAAAWKMYTLPENWGYGLAILKHVLGAGLIALQIWTSVSIYDSLGEFGWFFGDFFFDEAPKLTYSGIYRFLNNPERVLGLAGVWGAALITSSRAMIFLALLSHTLGIAFIQLVERPHMQKLYGRGLRQDAGLVRSIKRSLPPSFKQLHGSVDRILDESIEFIEEVLDTARPKLAAGVTTFVKDTSELFHKYPARITITRIEPDLAGYDMNDYSINVDTSDCITIRDGAEDKSEVLVFEYGSPIKVNWTAPLNHSKRDWVGLYMIGQNPSREVTNVSSWGRWVATNHGSFDSVLSEKGLIASDVVVSKPGTSNTSKKPSAKSSSGKKSSTSSSSHEVASGQMVFSGDKLWWTQGVFEFRYHHNGKHNVMATSRPFEIRIPKFDDGQIPSHVSSNGNGFMTTAIEQALLPIVQNCFDRDPEISPQTAEEPFGCETEGDLKYAKRVVYAVHQMFGIEFATEVVRADGNVQNLAWRICNAKKVLAPYSMRKSNGASTPTGESEEMK
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DXS_AROAE
Sequence: MPPYPLLHRIDSPFDLRKLDRRELPALAAELRAFLIESVSKTGGHLSSNLGTVELSIALHYIFDTPEDRIVWDVGHQTYGHKILTGRREAMSRLRQFGGISGFPRRSESSYDTFGTAHSSTSISAALGMAVAARNRGEQRRSIAVIGDGAMSAGMAFEALNNAGDMRDINLLVILNDNEMSISPPVGALTKILARMFSGRTYNAARRAGEKVLGVSPPMLDFARKVEEHVKGLITPGTLFEEFGFHYYGPIDGHDLDALIPTLQNLRKLNGPHFLHVITRKGQGYKLAEADPVLYHGVSTFDHTAGIQTAKGAAKLTYTQVFGDWLCDIAAQDEKVIGITPAMREGSGMVRFAQEFPNRYYDVGIAEQHALTFAAGLACEGFKPVVAIYSTFLQRAYDQLIHDIALQNLPVMFAIDRAGLVGADGATHHGAFDLSYLGCIPNLVVMAPADENECRQMLYTAYRHNGPAAVRYPRGGGMQVGPETAMSALPIGKGEIRRSGHRIALLVFGSLLFNALQAAEQLDATVANMRFVKPLDVTLIEELAASHDLLVTLEENIVIGGAGSEVARVLESLSDRPQLLRLGLPDTFIDHGDQSQLLESVGLDAPGIVAAIRRRFSPDNN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TPSD4_ABIGR
Sequence: MAEISESSIPRRTGNHHGNVWDDDLIHSLNSPYGAPAYYELLQKLIQEIKHLLLTEMEMDDGDHDLIKRLQIVDTLECLGIDRHFEHEIQTAALDYVYRWWNEKGIGEGSRDSFSKDLNATALGFRALRLHRYNVSSGVLKNFKDENGKFFCNFTGEEGRGDKQVRSMLSLLRASEISFPGEKVMEEAKAFTREYLNQVLAGHGDVTDVDQSLLREVKYALEFPWHCSVPRWEARSFLEIYGHNHSWLKSNINQKMLKLAKLDFNILQCKHHKEIQFITRWWRDSGISQLNFYRKRHVEYYSWVVMCIFEPEFSESRIAFAKTAILCTVLDDLYDTHATLHEIKIMTEGVRRWDLSLTDDLPDYIKIAFQFFFNTVNELIVEIVKRQGRDMTTIVKDCWKRYIESYLQEAEWIATGHIPTFNEYIKNGMASSGMCILNLNPLLLLDKLLPDNILEQIHSPSKILDLLELTGRIADDLKDFEDEKERGEMASSLQCYMKENPESTVENALNHIKGILNRSLEEFNWEFMKQDSVPMCCKKFTFNIGRGLQFIYKYRDGLYISDKEVKDQIFKILVHQVPMEE
What is the function of this protein?
Involved in defensive oleoresin formation in conifers in response to insect attack or other injury.  Involved in 34 sesquiterpene (C15) olefins biosynthesis.
What are the official names of this protein?
Delta-selinene synthase, Agfdsel1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_KLEP3
Sequence: MADKFHILLLNGPNINMLGTREPDKYGTLSLAEIVNRLTSEAAALNVSLDHLQSNAEYALIDRIHQAKDNVDYILINPAAFAHTSVAIRDALLAVNIPFIEIHLSNVHAREPFRQHSYLSDVAAGVICGLGADGYSYALQTAVKRLSQSH
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: P49_ASFWA
Sequence: MYHDYASKLLADYRSDPPLWESDLPRHNRYSDNILNSRYCGNKNGAAPVYNEYTNSPGKAEKGLQLSDLRNFSFMLNPQHKNIGYGDAQDLEPYSSIPKNKLFNHFKNYRPAFSTHTENLIKRNVVRTEKKTFPQVSGLKDTQKNCLTQPSSLPSLKNPKNSSVPSTRFSEHTKFFSYEDLPKLRTKGTIKHEQHLGDQMPGQYYNGYIPHQDVYNILCLAHKLPASVEKEIAGRGIPLGNPHVKPNIEQELIKSTSTYTGVPMLGPLPPKDSQHGREYQEFSANRHMLQVSNILHSVFANHSIKPQILEDIPVLNAQLASIKPVSPFLNKAYQTHYMENIVTLVPRFKSIANYSSPIPNYSKRNNGQAEYFDTSKQTISRHNNYIPKYTGGIGDSRLDSTFPKDFNASSVPLTSAEKDHSLRGDNSACCISSISPSL
What is the function of this protein?
Together with the penton and the other minor capsid proteins (M1249L, p17), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (By similarity).  Plays an essential role in the formation of infectious virus particles.  Especially required for the formation of the capsid vertices (By similarity).  During virion assembly, associates with the membrane and probably mediates the docking of the penton complex to the inner membrane, where it recruits the capsomers to form the penton core (By similarity).
What are the official names of this protein?
Minor capsid protein p49, p49.
What is the protein family that this protein belongs to?
Belongs to the asfivirus p49 structural protein family.
What are the subcellular locations of this protein?
Virion. Note=Localizes in close proximity to the capsid vertices.
Protein: PSBA_SPIOL
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, 32 kDa thylakoid membrane protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TBB5_GOSHI
Sequence: MREILHIQGGQCGNQIGAKFWEVICDEHGVDNTGKYNGDSDLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLATPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTACAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESDMNDLVAEYQQYQDATADDEYEEGEEEEEEAA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-5 chain, Beta-5-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NUOB_BREBN
Sequence: MELDLTSIAPELQEELNRNVMFTTLETVKGWVRSNSLWPLTFGLACCAIEMMGTGGARYDLDRFGVIFRASPRQSDVMIVAGTVTKKMAPLLRRLYDQMPEPKWVIAMGSCATAGGPYVRSYSVVKGVDQIVPVDVYIPGCPPNPAALIYGINKLQEKIRYEAKTGKQVTNL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FPG_PROMH
Sequence: MPELPEVETSRRGIEPHLVGNILHYAIVRNSKLRWPVSEKIKTLLDEPILSVKRRAKYLLIELNQGWIIVHLGMSGSVRILPEEQPEEKHDHIDLVFRDGKVLRYTDPRRFGAWLWCEDLATSSVLAHLGPEPLSAQFNAQYLYQQSKNKKIAIKPWLMDNKLVVGVGNIYANEALFSSGIMPDRKASSLTEQECDVLVNAIKTVLTRSIEQGGTTLKDFLQSDGKPGYFAQELFVYGRKDKACLICGHTIESIKQGQRSTFFCRHCQHGEITD
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PSA4_MACFA
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPNGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with TRIM5 in the cytoplasmic bodies.