PharMolix/UniProtQA huggingface dataset:
Protein: XRCC2_ARATH
Sequence: MGDDEARSWIRGDETAKQMLSRVLKDRAFLLIPPLHRVPLRAGNVVEITGASTSAKTQILIQAAISCILPKTWNGIHYGGLGKLVLFLDLDCRFDVLRLSQMLKHRLLQANWLGNGAWWQLEESNVKSCKSAEEKTKTVFDEELYASCMKRFLYVRCYDSLELLSSLKTLHYRIQQQEACGSQVGVLMIDSIGAFHWTDRLSSSLALETHNRKSLSLTNVVETIVQELKKLLLVHSLVVLATKGTIYEEKYPANENNRKVSSNDHFSGNVASKAQQPPFREFMPSSWQAFVTHKIIIRKSADYQSLQTGQQNLLAYSLEWLQPQLSRIDRFIVDDVRKLTTIKPFYSKLLLIYIVIPASSSHAVWYCHCLVT
What is the function of this protein?
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
What are the official names of this protein?
DNA repair protein XRCC2 homolog, X-ray repair cross-complementing protein 2 homolog, AtXRCC2.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASPQ_ACIGL
Sequence: KNNVVIVATGGTIAGAGASSTNSATYSAAKVPVDALIKAVPQVNDLANITGIQALQVASESITDKELLSLARQVNDLVKKPSVNGVVITHGTDTMEETAFFLNLVVHTDKPIVLVGSMRPSTALSADGPLNLYSAVALASSNEAKNKGVMVLMNDSIFAARDVTKGINIHTHAFVSQWGALGTLVEGKPYWFRSSVKKHTNNSEFNIEKIQGDALPGVQIVYGSDNMMPDAYQAFAKAGVKAIIHAGTGNGSMANYLVPEVRKLHDEQGLQIVRSSRVAQGFVLRNAEQPDDKYGWIAAHDLNPQKARLLMALALTKTNDAKEIQNMFWNY
What are the official names of this protein?
Glutaminase-asparaginase, L-ASNase/L-GLNase, L-asparagine/L-glutamine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LEC1_ECHLU
Sequence: QLHPLYLSGCPTTANCGSLGTPTNPALSCEHLKSVCADTASDFYYIESAGLYHKVFCEMDIEGGGWARYGRSNQGTTWNYVDEDAAEITLDIINASEVKEMTDLKYNRFLVQTDVVFKMKADDSVNPSRLTTRSLPWLEESPLFIPDYGNDHTRIEFPSGSVDRVTCIPGSSSKCGQGGGLPTANGLSKPFFFQSLFFSPRGTGASAHNDQWNRNKYTWDGSYYFVYAK
What are the official names of this protein?
Echinolectin 1, Echinometra lucunter lectin, ELL, Fribrinogen-related lectin.
Protein: CDK7_XENLA
Sequence: MEGIAARGVDVRSRAKQYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDTSLVLTPAHIKSYMLMTLQGLEYLHHLWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRIYTHQVVTRWYRSPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPGMSSLPDYVAFKSFPGTPLHLIFIAAGDDLLELLQGLFTFNPCARCTASQALRKRYFSNRPAPTPGNLLPRPNCSIEALKEQQNLNLGIKRKRTEGMDQKDIAKKLSF
What is the function of this protein?
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription.  Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression through the cell cycle.  Each different complex controls a specific transition between 2 subsequent phases in the cell cycle.  Required for both activation and complex formation of cdk1/cyclin-B during G2-M transition, and for activation of cdk2/cyclins during G1-S transition (but not complex formation).  cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex.  CAK activates the cyclin-associated kinases cdk1, cdk2, cdk4 and cdk6 by threonine phosphorylation, thus regulating cell cycle progression.  CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (polr2a), allowing its escape from the promoter and elongation of the transcripts (By similarity).  Involved in negative regulation of the meiotic maturation of Xenopus oocytes.
What are the official names of this protein?
Cyclin-dependent kinase 7, 40 kDa protein kinase, CDC2/CDK2,4-activating kinase, Cell division protein kinase 7, P40 MO15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=In the prominent nucleus of oocytes.
Protein: AROE_BACLD
Sequence: MKPIYGLIGNPVAHSMSPDIHNAALKDLSLEGHYHAFRVENEDLEDAVKGMRALGIQGFNVTVPHKVSIMKHLDRIDESAEALGAVNTVRREKEGLVGYNTDGAGFLKSLKPSLDRPLSELSILLIGAGGAARAIFTTLAAETPKRLDVANRTPEKALAFTQRFDGEARALSLQEAEADLSAYDIVIQTTSVGMHPNVEAAPLSLANAKETCLVCDIIYNPLKTALLHEAEAKGLKTLDGVGMFIGQAALAFELWTGHEPNMEKMKSIVLQQLGGKSC
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NATD1_XENLA
Sequence: MAHSVPESMDPNGPIRVEHDRKRRQFSVRLNGCHDRAVLLYEYVGKKTVDLQHTEVPDAFRGRGIAKHLAKAAMDFVVEEDLKAHLTCWYIQKFVKENPLPQYLEHLQP
What are the official names of this protein?
Protein NATD1, N-acetyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NATD1 family.
Protein: TRUA_PROMP
Sequence: MKRVALVIQYDGSYFSGWQRQKNAISVQETIENCLFKISNQIIKTFASGRTDAGVHASGQVIHFDIDFLIPIDRYADVLNSRLPHTIRILESVEVKSSWHACYSAVYRHYRYVINNNKIPNLFLNKWSWHRYQKYLDEVSMSIALDGMIGEHDFFAFQKSGSNRSTSVTTIKDIKLERTEDLILIDIKATGFLYGMVRSIVGQLVLVGEKKITPDIFKDRWVLKKKHDVRESAPAKGLCFVNSVYEENIFKRINKNDLFPKFVIRGYS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y3435_CLOB1
Sequence: MRYLVDTHTHTIVSGHAYTTFLENVQEASNIGLKVLGTTDHGPSMPGGPNLFYFNNFKVMPRKLKGVTLLHGCEANIIDFKGMLDIPDFTQKKLDVIIASLHDVCIRPGSVEENTEALINVMENPYVDILGHIGNPSFPINEEVVVKKAKEKNVLIEINNGSFVSRKGSEETCKKVANLCKKHKVNIIVGSDSHVCFQIGRFPKADNMLKEIGMPEELIINNEENKILKYLKNKGKLKDLNLD
What are the official names of this protein?
Probable phosphatase CLB_3435.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: HIS5_NITMU
Sequence: MTDIAIVDYGMGNLRSVAKALEHVAPEAVIAVTNNPEVVRKAERVVVPGQGAMPDCLRELDRLGLREAVRDAAANKPFLGICIGLQMLFDSSEEGNVSGLGIVPGRVKRFPASAMKDEKGQKLKVPHMGWNQVHQSVGHSLWKNIANDSRFYFVHSYYVEPADADSAGHSAYPFSFTCAVAKDNIFAVQFHPEKSHAAGLTLLGNFVRWKPV
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM10_HUMAN
Sequence: MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEADDGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELRNLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDVPALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGETTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVILKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKPKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYKKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKKKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKATASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
What is the function of this protein?
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.  Additionally, plays a role in preventing DNA damage during replication.  Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).
What are the official names of this protein?
Protein MCM10 homolog, HsMCM10.
What is the protein family that this protein belongs to?
Belongs to the MCM10 family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase. From early to mid-S phase located in discrete nuclear foci. In early S phase, several hundred foci appeared throughout the nucleus. In mid-S phase, the foci appeared at the nuclear periphery and nucleolar regions. In the late S and G phases localized to nucleoli.
Protein: RUVA_ZYMMO
Sequence: MIARLVGFLVEKNSDSAVIDVNGVGYLVQLSGRALDYFSEIEGEITVHIETQIREDSITLFGFASYLERDWFRLLTSVQGVGGKAALAILTALTCDAISVAISSGDKTMICRANGIGPKIAQRIINELKEKPAAIALFSSAKGDHLAVEDISQPAASAHHAGNFMADAVSALLNLGFKPAEAQRVVQLASEELGDQATLDSLVRLALRLSSKH
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: QUEC_STAAW
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ENO_PSEE4
Sequence: MAKIVDIKGREVLDSRGNPTVEADVLLDNGIIGSACAPSGASTGSREALELRDGDKSRYLGKGVLKAVANINGPIRDLLLGKDPADQKALDRAMIELDGTENKAKLGANAILAVSLAAAKAAAQDLDLPLYAHIANLNGTPGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKTFSDGLRMGTEIFHHLKAVLKARGLNTAVGDEGGFAPNLASNEDALGAIAEAVEKAGYKLGTDVTLALDCAASEFYEDGKYNLSGEGKSFDAEGFADYLKGLTERFPIISIEDGLDESDWAGWKILTDKIGEKVQLVGDDLFVTNTKILKEGIEKGIGNSILIKFNQIGSLTETLEAIQMAKAAGYTAVISHRSGETEDSTIADLAVGTAAGQIKTGSLCRSDRVSKYNQLLRIEEQLGAKAVYRGRAEFRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EFTS_CLOB6
Sequence: MISAKMVKDLREKTGAGMMDCKKALTECDGDLEKAVEVLREKGLAAAAKKSGRVAAEGIVSTYISEDMKNGSIIEFNCETDFVSVNELFVELANNLSKQAAFSNVSTAEELLEEKYIADESKLVKDVITELIAKLGENMNLRRIAKLSVDKGVITSYIHGGGRIGVIVKLACEKEDAKLAEIAKDVAMQVAATNPLFLNRDGVDTDTLEKEKEIYRVQALNEGKPEKVVEKMVMGRINKYYKENCLVEQLWVKNGDYTITKYLQEQSKEIGADITVEAFVRYEKGEGIEKKEEDFAEEVQRQMNQGK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STAS1
Sequence: MLDIKLFRNDPEFLKEKVAKRGMDSKVVDEVLELDEQRRQLISQAEEMKAERNKVSGEIAQKKRNKEDADDAIAAMRNLGDEIKVLDDTLNQVDVDLNDKLSRIPNIIHDDVPEGATDEDNIEVKRWGTPRTFEFEDKAHWDLVEELEMVDFERAAKVSGARFVFLTGDGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADSMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNYYRNEIIAPDVLPAKFTAQSACYRSEAGSAGRDTRGLIRLHQFDKVEMVRIEKPEDSWQALEDMTHHAEAILEELGLPYRRVILCTGDIGFGSSKTYDLEVWLPSYNDYKEISSCSNITDFQARRSNIRFKRDKNAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGSVTIPEVLVPFMGGKTVIRPTK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHOG_DROER
Sequence: MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHPAHPSHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSQGAGFKYLRTGTAKANVSQEAAISRLRVLVREDTLGEYRCVGWFGPLVVTSTIARLELASTSLVGAQESESPLQWRVAAGNSVLWSCGQQVQSNPSASWSYYRNGVEIKPEFIGTNGNLILSNVSSESSGSYSCQATNPASGERIQLPGLLQLQVTPEQRSLSKSPHLLKGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISDTRVQDAGTYICFQDNGVRPALEHYIKVHVEQPPQIVRPPWADLTNEGDRLKLECEATGVPSPEIYWLLNGHSSIDDTEAELSNNFLILHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSKQKQMYPPSPPNVTRLSDESVMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTLGGGAVLTLLLISICLCVCRRRSSRSRGNNPNKPRMAELRDDFVPLGNCSPTKQRQRTRHIHITLNPLAQQQQGMEEKNDTDQDAPYYQRPSSYDYDPGLRRMSSSSLRRSQRTLERAGGSNGSNNGNNNNLNQSTETGPVENPGKPGRVLMKRPRLSSRSENLSSGSLNSVGV
What is the function of this protein?
Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc).
What are the official names of this protein?
Interference hedgehog.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IHOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL30_PSYIN
Sequence: MATIKVTQVKSAIGRLPKHRATITGLGLRRINHTVELEDTPAVRGMVNKVHYMVKVEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYFA_AZOSB
Sequence: MDNLDQLVQQAQADFAGVSDSAQLEQAKARYLGKSGALTEQLKGLGKLPPEEKREAGAAINRAKTAIEAALEARRNALREAALLAQLAAEALDVTLPGRGAQGGGLHPVSRTLERIEMLFRSIGFIVADGPEIETDWHNFTALNTPENHPARSMHDTFYLEGRDDVLLRTHTSPVQIRTMLAHVKRHAEAAAMPEIRVIIPGRVYRVDSDATHSPMFHQVEGLWVGEKVSFADLKGVIADFLRKFFETEDLQVRFRPSFFPFTEPSAEIDVAFMSGPLKGRWLEIAGCGMVHPNVLRFGGVDPERYTGFAFGMGPDRLTMLRYGVNDLRLFFEGDLRFLSQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_THESM
Sequence: MDPYKVIVRPVVTEKAISMVERENKLTFIVDKRATKPDIKKAVETVYEVKVDKVNIVITMKGEKKAYVKLKPEYSASEVAARIGLF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CYSI_ECOLU
Sequence: MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RL35_LACDA
Sequence: MPKMKTHRASAKRFKRTGNGGLKRHHAFTGHRFHGKTKKQRRHLRKAAMVSRSDLKRIKQMLSQMR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MMP8_HUMAN
Sequence: MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
What is the function of this protein?
Can degrade fibrillar type I, II, and III collagens.
What are the official names of this protein?
Neutrophil collagenase, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granules.
Protein: RS10_CAMLR
Sequence: MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPVPMPTKIKRYTVLKSPHINKDSREQFEMRIHARMLDIVAATPDTVDSLTKLDLAPEVNVEVRAMGK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: P1_BPPH6
Sequence: MFNLKVKDLNGSARGLTQAFAIGELKNQLSVGALQLPLQFTRTFSASMTSELLWEVGKGNIDPVMYARLFFQYAQAGGALSVDELVNQFTEYHQSTACNPEIWRKLTAYITGSSNRAIKADAVGKVPPTAILEQLRTLAPSEHELFHHITTDFVCHVLSPLGFILPDAAYVYRVGRTATYPNFYALVDCVRASDLRRMLTALSSVDSKMLQATFKAKGALAPALISQHLANAATTAFERSRGNFDANAVVSSVLTILGRLWSPSTPKELDPSARLRNTNGIDQLRSNLALFIAYQDMVKQRGRAEVIFSDEELSSTIIPWFIEAMSEVSPFKLRPINETTSYIGQTSAIDHMGQPSHVVVYEDWQFAKEITAFTPVKLANNSNQRFLDVEPGISDRMSATLAPIGNTFAVSAFVKNRTAVYEAVSQRGTVNSNGAEMTLGFPSVVERDYALDRDPMVAIAALRTGIVDESLEARASNDLKRSMFNYYAAVMHYAVAHNPEVVVSEHQGVAAEQGSLYLVWNVRTELRIPVGYNAIEGGSIRTPEPLEAIAYNKPIQPSEVLQAKVLDLANHTTSIHIWPWHEASTEFAYEDAYSVTIRNKRYTAEVKEFELLGLGQRRERVRILKPTVAHAIIQMWYSWFVEDDRTLAAARRTSRDDAEKLAIDGRRMQNAVTLLRKIEMIGTTGIGASAVHLAQSRIVDQMAGRGLIDDSSDLHVGINRHRIRIWAGLAVLQMMGLLSRSEAEALTKVLGDSNALGMVVATTDIDPSL
What is the function of this protein?
P1 is the major inner capsid (core) protein of the polyhedral procapsid, which is responsible for genomic replication and transcription.  Forms a dodecahedral shell from 60 asymmetric dimers.  Binds to RNA and may be involved in genomic packaging.
What are the official names of this protein?
Major inner protein P1.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein (120 copies).
Protein: RNFA_ALCBS
Sequence: MTEYVLILISAVLVNNFVLVQFLGLCPFMGVSNKVETAMGMSLATTFVLTLSSVLAYLTWAYILVPFELEYLRTISFILVIAVAVQFTEMFVKKASPLLYRVLGVFLPLITSNCAVLGVALLNVRQEDATFMSSLTYGFGAAIGFSLVLILFAAMRERIAVADVPEAFRGPSIGLITAGLMSLAFMGFSGLIKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BCS1_XENLA
Sequence: MPFADFVAALKDNPYFGAGFGLVGVGTALALTRKGAQFGMIAFRRHYMITLEVPSKDKSYQWLLSWISHYAKNTQHLSVETSYLQHESGRISTKFDFVPSPGNHFIWYRSKWIRIERNREKQMIDLHTGTPWESVTFTALGTNRNIFFNILQEARELALKQQVGKTVMYNAVGAEWRQFGFPRRRRPLSSVVLEQGISEKIVQDVKGFIENPKWYSDRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSICLMSLSDSSLSDDRLNHLLSVAPQQSIILLEDVDAAFVSRDLNKQNPTAYQGMGRLTFSGLLNALDGVASTEARIVFMTTNHIDRLDPALIRPGRVDVKQYVGHCTNWQLSQMFLRFYPDQTAGQSEAFASAALSSSDKISAAQVQGHFMMHKTDPDGAIQNVCLATM
What is the function of this protein?
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.
What are the official names of this protein?
Mitochondrial chaperone BCS1, BCS1-like protein.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SUCD_PSEAE
Sequence: MSVLINKDTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVKEAVEATGAEASVIYVPAPFCKDSILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVRLIGPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYEAVKQTTDAGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPQTEAIVMIGEIGGSAEEEAAAFIKANVTKPVVSYIAGVTAPPGKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKKA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.  Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
Protein: OPRM_MOUSE
Sequence: MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
What is the function of this protein?
Isoform 9 is involved in morphine-induced scratching and seems to cross-activate GRPR in response to morphine.
What are the official names of this protein?
Mu-type opioid receptor, M-OR-1, MOR-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome. Note=Is rapidly internalized after agonist binding.
Protein: Y602A_HAEIN
Sequence: MXVNFDETSKNNDKLSNNITDWQQNIEKSATSFLNHFIRISPKQNSNKKELLAPNQDIYLRENIRLRLQLAIMAVPRQQNELYKQSLEAVSSWVRSYFDTNAEVTQNFLKLVDGLTDTSIYVDVPEQLKSLTLLDKYLNRTALDVQKVEIEADKAIDTMPQVEAVKPTQSESQQ
What are the official names of this protein?
Uncharacterized protein HI_0602.1.
What is the protein family that this protein belongs to?
To E.coli HemX C-terminal region.