PharMolix/UniProtQA huggingface dataset:
Protein: SELO_MORMI
Sequence: MRQKTATITRRDKSFTGHYVPVKPTPIKDPEYVAHSKNLFSELGFADSMAESADFVRMFSGDMSGVPVPMRQVGWASGYALSIYGTEYTQQCPFQTGNGYGDGRAISVLETLIKGQRWEMQLKGGGRTPYCRGADGRAVLRSSIREFLAQDHMHALGVPTSRSLSLYVSKTETVKRPWYSQGSRSENPDMLISEAVAISTRVAPSFIRVGQLELFARRSRSNEHPKAMEELEKIVLHLIDREYADVIDTQLATPEKIVLLAREFRGRLTSMVANWIRVGFCQGNFNSDNCAAGGFTLDYGPFGFCDVFNPYYQPWTGGGNHFSFMNQPNAAQRNFDMFCSALRPLLVSHQQDLLAFDEIQSEFLAVMDTKMKAMWATKLGLINLKTESDKALCNVLIKELQTLMMQAPVDYTIFFRELSSIPDDIGPLKKSFYSNLYNDAADDPDTLALEKYWIEWLEKWQMLLNSTCDAKGISSRASEDIAMQMKLVNPKYVLREWFVMPAYQQATAGDYSLIQELQAVMTQPYAEQSKELEDKYYRLKPLEFFEVGGLSHLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: MYB40_ANTMA
Sequence: MDKKPCNSHDVEVRKGPWTMEEDLILINFISNHGEGVWNTIARSAGLKRTGKSCRLRWLNYLRPDVRRGNITPEEQLLIMELHAKWGNRWSKIAKHLPGRTDNEIKNYWNRTRIQKHIKQAEASFIGHINPEHSNEQASTSLLSSSCHADHAVESYSSSFNGNMGNNVQYPNHFPTESNDYFWSMEDLWSMQLPNNGG
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
Myb-related protein 340.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_LISW6
Sequence: MTFLEEILAQKVIEVAEMPLEKVKDKRETYSFYDFLKAHPEKMQLIAEVKRASPSKGEINMGVDPVTQAKSYEAAGAGMISVLTDPVFFKGSIEDLREVARNVKIPVICKDFIISEKQLIRARNAGATVVLLIISALSEAALKTLFEQATALDLEVLVEVHDQKELAIAQKLGAKLIGVNNRNLHTFEVDIAVSEKLARDFSTNVCFISESGFKTAEDVGRVSKEYNAVLVGEALMREKSPEVAAKRLKVKR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ARGR_BIFAA
Sequence: MTDHTPALQRPATRTARLSAIEQALLTRIVTSQSQLSQILADQGIEVTQATLSRDLDEIHATKTRLADGTVAYAVGKQNIDEHPASNPDAKTEQQISRVLSGLVTSVAAARNLVVVHTPSGAAQYVASVIDKQPIEGVLGTIAGDDTVMVICSEDDVAKRRAQWLLDVASKA
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_RHIWR
Sequence: MARFIFITGGVVSSLGKGLMAASLAALLQARGYKVRIRKFDPYLNVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFTGVPGRQSDNITSGRIYQTIIQKERRGDYLGATVQVIPHVTDAIKEFARADTEGLDFVLCEIGGTVGDIESLPFMEAIRQLRNDLGRGNSIFVHLTLVPYIAAAGELKTKPTQHSVRDLTSLGIQPDVLVCRCDRPLPEGERAKIALFCNVPTEAVIPALDASSIYGVPLQYHEEGLDEAVLSAFGIEAKDEPDLTRWTEIMDRLENPEGEVTIGVVGKYVGLLDAYKSLHEALVHGGIANRVKVNIRWIDAELFEQEEGGIAAQLEPMHAILVPGGFGERGSEGKIAAVRFARERKVPYFGICLGMQMACIEGARNTAGIAAASTTEFGPTDEPVVGMITEWMSEDGLQKREAGGDLGGTMRLGAYDARLSGNSHAATIYGATDISERHRHRYEVNVHYRESLERGGLVFSGMSPDGELPEVVERPDHPWFVGVQFHPELKSKPFDPHPLFASFIAAALQQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL11_ECOUT
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ATPD_COXB1
Sequence: MALHLTLARPYAKAAFADGQKANQLEAWLAVFTAFSKIIKNKEVARQIINPKFSDKEIKTLLFDLIQTIEPESTKQLKDKIDHFLQLLIDEKRLMILPDIALVYQQLLNKYQDIIEASVTYVFPLNDEHRQQIQKQLEKRFNAEVKLKMIKDESLLGGVIIRAGNWVMDGSIKGKLTRLAENLKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRAZ_PSEAE
Sequence: MFRGANAISLDAKGRLAMPSRYRDELVSRCAGQLIVTIDAVDPCLTVYPLPEWELIEAKLRELPSLREETRRLQRLLIGNAVDLELDGNGRFLIPPRLREYAKLDKRAMLVGQLNKFQLWDEDAWNAMAEADLAAIKQPGGLPDELRDLIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RISB_STAAW
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RL22_THEAB
Sequence: MQVLIKRNGMKRSKFHRERKEKLATMPVYEARAVAKFVRISPRKARSVANSIKGKNVSEAFTILEFSPKKAARLIKNVLKSAVANAVNNHGLNEENLYVYTCYVNDGPRMKRIWPRGRGSADIIQKRMSHITVIVRDKEAEKAAKEEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YHAZ_BACSU
Sequence: MADLKEIYNEELISQLIHHVRSSYPDFNKNRFLDTLRLEDWPELTLKERMRRVTVSLYETLPKQYVEALTILRDTAPHFKGLSGILFPDYVEQYGLAHWEESIKALESFTQYSTSEFAVRPFLLLDQEKMIAQLLAWSEHKNEHVRRLASEGSRPRLPWGKSIPALKSDPSPVLPILEKLMQDESLYVRKSVANNLNDISKTHPHLLRKVADQWYGTHPHTDWIIKHAYRTLLKKGDKQALALFGYENADSIQLHDLTCQPKRIVIGESLEFSFYIHSDRDQKVRIEYAIDFVKARGQRHQKVFKITETNIRKNETKSYTRIQSFKDLTTRKHYKGIHTLSVIINGEVKDSLDFQVC
What are the official names of this protein?
Uncharacterized protein YhaZ.
Protein: GLYA_SALAR
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIIPYGIDASGKIDYDDMAKQAQEHKPKMIIGGFSAYSGVVDWARMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGDEDLYKKLNSAVFPSAQGGPLMHVIAAKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDNINDEATIERVKTKVLDICARFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POT10_ARATH
Sequence: MAGRVESSIGGGEIDEEGDERGSMWDLDQSLDQPMDEEAGRLRNMYREKKFSAFLLLQLSFQSLGVVYGDLGTSPLYVFYNTFPRGIKDPEDIIGALSLIIYSLTLIPLLKYVFVVCKANDNGQGGTFALYSLLCRHAKVSTIPNQHRTDEELTTYSRTTFHERSFAAKTKRWLENGTSRKNALLILVLVGTCMVIGDGILTPAISVLSAAGGLRVNLPHINNGIVVVVAVVILVSLFSVQHYGTDRVGWLFAPIVFLWFLFIASIGMFNIWKHDPSVLKAFSPVYIFRYFKRGGQDRWTSLGGIMLSITGIEALFADLSHFPVSAVQFAFTVIVFPCLLLAYSGQAAYLRKYPHHVEDAFYQSIPKRVYWPMFIIATAAAIVASQATISATFSLIKQALAHGCFPRVKVVHTSRKFLGQIYVPDINWILMILCIAVTAGFKNQNQIGNAYGTAVVIVMLVTTLLMMLIMILVWRCHWVLVLLFTLLSLVVECTYFSAVLFKVNQGGWVPLVIAAAFLVIMYVWHYGTLKRYEFEMHSKVSMAWILGLGPSLGLVRVPGIGLVYTELASGVPHIFSHFITNLPATHSVVIFVCVKNLPVYTVPQEERFLVKRIGPKNFHMFRCVARYGYRDLHKKDDDFEKRLFESLFLFLRLESMMEGCSDSEDYSVCGSQQRQSRDGVNGNGNEIRNVSTFDTFDSIESVIAPTTTKRTSHTVTGSSQMSGGGDEVEFINGCRDAGVVHIMGNTVVRARREARFYKRIAIDYVYAFLRKICRENSAIFNVPQESLLNVGQIFYV
What is the function of this protein?
Putative potassium transporter.
What are the official names of this protein?
Potassium transporter 10, AtPOT10.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSGD_ECOLI
Sequence: MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
What is the function of this protein?
The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon.  Plays a positive role in biofilm formation.  May have the capability to respond to starvation and/or high cell density by activating csgBA transcription.  Low-level constitutive expression confers an adherent curli fimbriae-expressing phenotype, up-regulates 10 genes and down-regulates 14 others.
What are the official names of this protein?
CsgBAC operon transcriptional regulatory protein.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Note=In experiments done with low-level constitutively expressed protein.
Protein: PPNP_PSEPG
Sequence: MFQVNEYFNGTVKSIAFAGEEGPATVGVMAPGEYEFGTAKREIMHVVSGALTVKLPGSDNWETFNAGDKFNVAADSKFQLKVKVDTAYLCEYRD
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: IF2P_ARCFU
Sequence: MSKKKEEAKALRTPIVAVLGHVDHGKTTLLDRIRKSKVVAKEAGGITQHIGATEVPLDVIKQICKDIWKVEVKIPGLLFIDTPGHKAFTNLRRRGGALADLAILIVDINEGFKPQTEEALSILRTFKTPFVVAANKIDRIPGWQSHEDTPFMKSYAMQEDFAKQNLENRLYNLIAELYQRGFSAERFDRISDFTRTVAVVPISALKGEGIPELLLILVGLAQRYLEKNLRLHIEGKGRGTVLEVKEERGLGVTCDAILYDGTLKVGDRIAIAGKDEVIVTNVKAILKPPPVREMRVESKFQSVKSVTAAAGIKIVAPNLENVLAGSEFEVVESEEDIKKFEERVRKEYEEIAIRTDEEGVVLKTDTLGSLEALINELRQEGIPIKKAEVGDVDKRDVVDASANKDELNKVVLAFNVKLLPGVEEEAKKYGVRIFSHEIIYTLIESFVKWREEERLARERQKVEALIKPGKIKLLKEFIFRRSKPAIVGVRVLAGELRRGVDLIKPDGTKVGAVRTMQKEGKNVAIASAGDELAIAIEDVTIGRQLEGDEELYVDVPERHAKVIERDLLDSLDEETKRAFKEFLEIKRKDNPFWGK
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2 (By similarity).
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: KDUI_SHIFL
Sequence: MDVRQSIHGAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFNDMDHVGVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: Y5262_BREBN
Sequence: MTELGNDKAMNLLIITGMSGAGKTVAVQSLEDLGFFCVDNLPPVLIPKFAELVKQSGGSIERVALVIDLRGREFFENLAVTMESLNQMNGLSYHILYLDANDQTLVSRYKETRRRHPLSPNGSPLEGIHAERRLLEEMKGWAHQIIDTSQMKPVQLREKIINQYGQQGSPLTINVLSFGFKYGAPIDADLMFDVRFLPNPHYVEDLRPKTGCDPDVAEYVMQHKDTKEFLEKLTDFLGYTLPHYQREGKSQLVIGIGCTGGKHRSVAIAEHLGEAFGKDFSVRVSHRDMEKNK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BBR47_52620.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SMC5_YEAST
Sequence: MTSLIDLGRYVERTHHGEDTEPRSKRVKIAKPDLSSFQPGSIIKIRLQDFVTYTLTEFNLSPSLNMIIGPNGSGKSTFVCAVCLGLAGKPEYIGRSKKVEDFIKNGQDVSKIEITLKNSPNVTDIEYIDARDETIKITRIITRSKRRSDYLINDYQVSESVVKTLVAQLNIQLDNLCQFLSQERVEEFARLKSVKLLVETIRSIDASLLDVLDELRELQGNEQSLQKDLDFKKAKIVHLRQESDKLRKSVESLRDFQNKKGEIELHSQLLPYVKVKDHKEKLNIYKEEYERAKANLRAILKDKKPFANTKKTLENQVEELTEKCSLKTDEFLKAKEKINEIFEKLNTIRDEVIKKKNQNEYYRGRTKKLQATIISTKEDFLRSQEILAQTHLPEKSVFEDIDIKRKEIINKEGEIRDLISEIDAKANAINHEMRSIQRQAESKTKSLTTTDKIGILNQDQDLKEVRDAVLMVREHPEMKDKILEPPIMTVSAINAQFAAYLAQCVDYNTSKALTVVDSDSYKLFANPILDKFKVNLRELSSADTTPPVPAETVRDLGFEGYLSDFITGDKRVMKMLCQTSKIHTIPVSRRELTPAQIKKLITPRPNGKILFKRIIHGNRLVDIKQSAYGSKQVFPTDVSIKQTNFYQGSIMSNEQKIRIENEIINLKNEYNDRKSTLDALSNQKSGYRHELSELASKNDDINREAHQLNEIRKKYTMRKSTIETLREKLDQLKREARKDVSQKIKDIDDQIQQLLLKQRHLLSKMASSMKSLKNCQKELISTQILQFEAQNMDVSMNDVIGFFNEREADLKSQYEDKKKFVKEMRDTPEFQSWMREIRSYDQDTKEKLNKVAEKYEEEGNFNLSFVQDVLDKLESEIAMVNHDESAVTILDQVTAELRELEHTVPQQSKDLETIKAKLKEDHAVLEPKLDDIVSKISARFARLFNNVGSAGAVRLEKPKDYAEWKIEIMVKFRDNAPLKKLDSHTQSGGERAVSTVLYMIALQEFTSAPFRVVDEINQGMDSRNERIVHKAMVENACAENTSQYFLITPKLLTGLHYHEKMRIHCVMAGSWIPNPSEDPKMIHFGETSNYSFD
What is the function of this protein?
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage.  Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
What are the official names of this protein?
Structural maintenance of chromosomes protein 5.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YD366_YEAST
Sequence: MVTIGSSSLVLFLFFVVFVQITYTALHRFSRLLCTFFSKIIEEGCVWYNKKHRFPNLYKYIYVYVYILHICFEKYVNVEIIVGIPLLIKAIILGIQNILEVLLKDLGIHKRESAILHNSINIIIIILYVYIH
What are the official names of this protein?
Uncharacterized protein YDR366C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPEE_THET8
Sequence: MDYGMYFFEHVTPYETLVRRMERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEYIYHETLVHPAMLTHPEPKRVLIVGGGEGATLREVLKHPTVEKAVMVDIDGELVEVAKRHMPEWHQGAFDDPRAVLVIDDARAYLERTEERYDVVIIDLTDPVGEDNPARLLYTVEFYRLVKAHLNPGGVMGMQAGMILLTHHRVHPVVHRTVREAFRYVRSYKNHIPGFFLNFGFLLASDAFDPAAFSEGVIEARIRERNLALRHLTAPYLEAMFVLPKDLLEALEKETMVSTDQNPFYVTPEGEARQAPYKG
What is the function of this protein?
Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions.  It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively.  Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to agmatine to yield N1-aminopropylagmatine.  An efficient aminopropyltransferase activity has been also observed with norspermidine which produces thermine, and spermidine which produces spermine and thermospermine.  The aminopropyl activity with homospermidine, mitsubishine, thermine, 1,3-diaminopropane, putrescine (1,4-diaminobutane), spermine and caldopentamine are very low.  The reaction involves a nucleophilic attack on the C-3 methylene of the propylamine moiety adjacent to the positively charged sulfur of decarboxy-AdoMet.
What are the official names of this protein?
Polyamine aminopropyltransferase, Agmatine aminopropyltransferase, N1-aminopropylagmatine synthase, Norspermidine aminopropyltransferase, Spermidine aminopropyltransferase, Spermine synthase, Thermine synthase, Thermospermine synthase, Triamine/agmatine aminopropyltransferase, TAAPT.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNE_DROSE
Sequence: MDQEVMDFFDFSKELNRVPGAPQGYISSDPWLMATESKSSEVPNRETIGTDYVTKIVAKEKCRLNRTLLEYQPQGKRNRTLDDLDTDDEAEETEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAAINAHPVIIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFATTNSIPPVITTNHGRKHSIEKFYRDQLGSIIWNEEDVGDQHVPEINKHGYRAAVKIIVIIDNMERKAAIQSRLSYDETLRYGAVLIFLPGIYEIDTMAENITCMLENDRNIKVLIVRCFSLMTPENQRDVFNPPPPGFRKIILATNIAESSITVPDVSYVIDFCLTKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMAEFGIPEMLRLPLQNSVLKAKVLNMGSPMEILALALSPPNLSDIQNTILLLKEVGALYLTVDGVYDALDGDLTYWGTIMARLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTNGLFAHDGGRTQLGDSFWMHYIFADGSGSDLVAIWRVYLTYLSLVEIGHDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCMHLGLIPFSVNPSQMMDDREKAIMLKVIIAGAFYPNYFTRSKDTCADTDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVTFQEGSQKVFVTFKQDDWIADSSKFVPVSGRVQSEVYKAVMMRQNRLERPIHIMNPSAFMSYVQQRGIGDVIEGRWIPPTKPLNVELLALPSVFDKTISGLITCIVSCGKFFFQPQSFAECIGNMSEIFNAPQQLRNYVNNAGDITKGMMVLAKRDSYFQRATVIRPENQSNRQPMFYVRFIDYGDCALLSMQQMRLMPRELTEQYGDLPPRVFECRLAMVQPSSMVSGNNRWSTAANDMLRSVAKSGLIDIEVYSLFNNVAAVLIYMRDGIINDKLVELMLCRRSDEDYMSRKDHDFRLRRQESARYLSSAQRQQINEEYMRSCQLPEDHDLRPPPPEKCKTVVILKGPYSPLECTMQCITRVGSSKRVNIDHLSVNALLLDADPQDHHDHLIVAHEIAENRNGHTLTARGTTLMPNVQGFGALMVMLFSPTMQLKCNREGTSYVSVLGGLGCDPETNEPYFPEHDVLINLDVNILEDDVILINQIRYYIDSVFFNFKDENNPAVSANERVSIYTQLRSIINRLLCKDRRYIERNMSNADFEWETHPDLPPPNEPFGKRAIFPMHSLTELQEEDTGRLVQLRENCSMLHKWRNVEGTLPHMTCKLCNQLLDSVPQLRLHLLTILHRDREKQIDYCNQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: RIMO_RHOP5
Sequence: MEQAPAPKISFVSLGCPKALVDSERIITRLRAEGYELARKHDGADIVIVNTCGFLDSAKQESLGAIGEAMAENGKVIVTGCMGAEPEQIEAAYPNVLSITGPQQYESVLEAVHRALPPIHNPHLDLMPPQGIKLTPRHYAYLKISEGCNNRCSFCIIPKLRGDLVSRPAAEVLREAEQLVKAGVKELLVVSQDTSAYGVDLKYAESQWQDRAVRARFYDLAKELGSLGAWVRLQYVYPYPHVDEVIELMAKGAVLPYLDIPFQHAASSVLTRMKRPAAQDKTLARIKRWRETCPDLALRSTFIVGFPGETEQEFAELLDWLEEAEIDRLGAFKYEPVQGAASNALPDQIPAEVKQQRWDALMARQQKISARRLKRKVGTRQQVIIDEAGPNGAKGRSKADAPQIDGHVYLSSRRPLRVGELVTAKIDRADAYDLHGTVAGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRRCA_XENLA
Sequence: MMEESGIETTPPSTPPPSTIGTSVPAATTAISTPVPPIFSSPLAAPVFSPLPSFAQPIFSTPLPSSVPPLRTSVPLTYAPPLPVTGVHSPPAHTSVPAAFSSPLPAFSSPPSFPPPPLNTTPGPVLTAPPTGPPVGGFSMSSHYDITKGHAGRAPQTPLMPTYSAAPVTVLPNPVIQAPLAGSGSSITFPEEPEDSRVHTMHVDGSAGGIWGFFKGVAGNPMVKSVLDKTKHSMETVITTLDPGMASYIRTGGEMDIVVTSVKEVKVAAVREAFQEVFGMAVVTGEDGQSNIAPQPVGYAAGLKGAQERIDSLRRSGMIHEKQPAVSVENFIAELLPDKWFDIGCVIIDDPTHGIRLETFTQATPVPLEYVQQAQNLTPQDYNLRWSGLSVTVGEVLERSLAHVCRTDWHVAFTGMSRRQMIYSAAKALAGMYKQRLPPRIL
What are the official names of this protein?
Protein PRRC1-A, Proline-rich and coiled-coil-containing protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the PRRC1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: PHOP2_HUMAN
Sequence: MKILLVFDFDNTIIDDNSDTWIVQCAPNKKLPIELRDSYRKGFWTEFMGRVFKYLGDKGVREHEMKRAVTSLPFTPGMVELFNFIRKNKDKFDCIIISDSNSVFIDWVLEAASFHDIFDKVFTNPAAFNSNGHLTVENYHTHSCNRCPKNLCKKVVLIEFVDKQLQQGVNYTQIVYIGDGGNDVCPVTFLKNDDVAMPRKGYTLQKTLSRMSQNLEPMEYSVVVWSSGVDIISHLQFLIKD
What is the function of this protein?
Phosphatase that has high activity toward pyridoxal 5'-phosphate (PLP).  Also active at much lower level toward pyrophosphate, phosphoethanolamine (PEA), phosphocholine (PCho), phospho-l-tyrosine, fructose-6-phosphate, p-nitrophenyl phosphate, and h-glycerophosphate.
What are the official names of this protein?
Pyridoxal phosphate phosphatase PHOSPHO2.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.
Protein: APT_LEPBJ
Sequence: MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQDKGITKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPAETVSEEYDLEYGKDVIEIHKDAVQPGDKILLMDDLIATGGTMIAAVKLLKKLGAQIYEAGVIIDLPDLGGSKKLQEKLEVPVFAICEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.