PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_CLONN
Sequence: MNKGAFITLEGPEGSGKTTIVKMIEKYLSENNIEYISTREPGGINISEQIRDVILNKDNVAMDARTEALLYVASRRQHLAERVIPAIKEGKVVICDRFIDSSLAYQGYARGIGIDEVMAINEFAIDGYMPDLTLYLDIEPEVGLKRISKNNEREVNRLDLEALDFHKKVREGYFKLLEKYPNRIKKINANQPVDKVFEEVKGFLK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FABH_STRP1
Sequence: MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDGAGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVRI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_BORT9
Sequence: MLKKFRDLTLEDIKAKRLSLKKEYMDLRFKAVVGHVENPLKKRELRRDIARLNTIVHEYEIGIRKV
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ATPB_DESRM
Sequence: MNVGHIVSVIGVVVDVEFAPGQVPDIYSAVKIRTEDQEDKSTKWNLTLEVAQHLGNNRVRCIAMSSTEGLKRGMKVVSTGKAISVPVGRPVLGRLLNVLGEEADGLEPIKAEKYYPIHRPAPALVDQSTKAEMLETGIKVIDLMIPFLKGGKIGLFGGAGVGKTVIVMELINNIAKQHGGISVFAGVGERTREGNDLYHEMKEAGVLEKTIMVFGQMNEPPGARLRVGLTGLTMAEFFRDEEGADTLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTRKGSVTSVQAIYVPADDLTDPAPANAFAHLDATVVLSRAISELGIYPAVDPLDSTSRILDPQVVGKEHYECARGVQSVLQRYKELQDIIAILGMDELSDEDKLTVARARKLQRFLSQPFHVAETFTGRPGKYVSLKDTIRSFNEILAGKHDALPEQAFYMAGAIEEVMENAKRIEAGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DHYS_METKA
Sequence: MKRETFRYRGDMDLDGFLREMERVGALGAGRLGRAARILEKMWSSDDVTVLLTVAGPAVAGGLGELFERLIREGLVDAVITSGANVVHDALDALGGIHVCLGERNVDGYGRVHDTHIPTEAFEKFEHFMREVLSDLSGRVSCRELLWEMGKRLESGFLRAAADEGVPIYSPGILDSMVGLHVWIHSQDHDFHLDLVDDMHHLADLVFEAEELGAIILGGSVPKHFAMGAAMLRGGLDYAVQITMDRPETGSLSGAPLEEGKSWEKVREDAEVATIVGDYLIIFPLLASGVMQRLGIV
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: ATPB_STACT
Sequence: MGVGRVTQIMGPVIDVRFNHDELPKINNALVLDVPKKDGTTESLTLEVALELGDDVVRTIAMDSTDGIKRGDDVKDTGRPISVPVGDDTLGRVFNVLGDPIDNAGPIPESVPREPIHRQPPPFDELSTKVEILETGIKVVDLLAPYIKGGKVGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDVKGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTMKGSITSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYDVARRVQATLQKYRELQDIIAILGMDELSDEDKSTVERARRIQFFLSQNFHVAEQFTGQKGSYVSVKRTVEDFKDILEGKYDHIPEDAFRLVGSMDDVLEKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNC_ECOLU
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQIB_SHIFL
Sequence: MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQYRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARYDYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY
What are the official names of this protein?
Uncharacterized protein YqiB.
Protein: NTM1_SCHPO
Sequence: MDPEKFYSDAIDYWNGVQPTVDGMLGGLGTGRIPQTDVVGSRTFLNRLNYRIGKIENLVAADCGAGIGRVTENVLLKIASHVDLVEPVENFISTAKKQLATKPCSFINVGLQNWTPEKNRYGLIWNQWCLSHLTDEDLIAYLSRCCEAIQEKGVICVKENVSSFEDTFDPIDSSVTRCEQSLKSLFKKANLVVVAETLQHGFPEELFPVKMYALVPHSS
What is the function of this protein?
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved.  Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif (By similarity).
What are the official names of this protein?
Alpha N-terminal protein methyltransferase 1, Translation associated element 1, X-Pro-Lys N-terminal protein methyltransferase 1, NTM1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. NTM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_CLOK5
Sequence: MTKKIYIFDTTLRDGEQTPKVSLNINDKITIAKQLQKLSVDVIEAGFPKASHGDFEAVKAIAESIQGPVIVGLARASKEDIDCAWEALKGSLKPRIHIFLATSDIHMEHKLKMKPEEVLKRAADMVRYAKGLCPSIEFSPEDATRTRPEFLYKVLEAVIEAGADVVNIPDTVGYTTPVEYGAFIRGIKENVKNIEDAIISVHCHNDLGLAVANSLAAIESGAEQVECAINGLGERAGNAALEEIVMAISTRADSFNCHTDIVTEEITKTSSIVSHVTGMQVQGNKAIVGANAFAHESGIHQHGVLNCRETYEIMTPESVGLKKNFIVLGKHSGRHAFVEHLHEMGYKDLSVEKTDEIFKKFKELADKKKHISDEDIESLVKNEIFHVPEVFKLKYYQVFTGNTVVSTSTVEIECNGKKLSEASCGDGPVDATFKAIEKATGIDVTLNDYFIKAVGSGKDAMGEVTVRIEKEGKIFSAKGISTDIVEASGIAFINAVNKLYYETYSKDLQKISAN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: ACP_NAUPA
Sequence: MALFDEVKEVIVEQLNVAPEEVKPEAKFVEDLGADSLDVVEMIMALEEKFEIEIPDSEAEKIQTVQDVIDFIEKAKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS2_METM6
Sequence: MRFKLDGRIIFSKDVEEETQKDIVEVLENGDIFLKGVPEGKENEASKIETYEFDGKDLKLKMTSGTYTRAHEGIVRLKKPIMEKVGRKHQIGIRDVAIDRYVVTITAEPSKVSELKGLKVPECEVELEGEKINIVFENLGDGELKRNIIDRAIKFVKNELDKQDKDLTFEVCKIAPGTIVSDYKAKREITFDTDPTELAEPYGWVKRFPGRGQWFYTAPMAKLFRAFESLIIEECIDKIGFDECLFPKLIPLDVMYKMRYLEGLPEGMYYVCPPKREPEMFQDFVNEMMIKKEIPIEKLKTLLRDPAYVLAPAQCEPFYTFFDHELVDVDHPSKFFDKSGWTYRWEGGGAKGLDRVNEFLRGECVWMGTPEFVETVRDDTLKYAENLAEKLDLEYWTEVGDDPFYLEGRKTEARGIEFPDVPKYEMRLWLPHIKEERKGVAVTSANIHGTHFVEGFGIKDYKERKVWTGCTGYGLTRWVIGFLAQYGYNYDDWPELIQKKVGKLPEIPKLITWP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Type-2 serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_DECAR
Sequence: MPSGKEIRNKIKSVENTRKITKAMEMVAASKMRKAQDRMRAARPYGEKIRRVAGNLSHALTEYRHPFLVNREQAAVGLILVTSDKGLCGGLNSNLLRVAVSKMKEFESQGKKLQATCIGNKGFGFMQRSGAKIVSHVTGLGDTPHLEKLIGAVKVQLDAYMNGEIDALYIGYTRFINTMKQEPVFEKLLPLSGDAVGSAKTKWDYVYEPEAKSVIDDLLIRYVEALIYQAVAENMASEQSARMVAMKSASDNAKTVIGDLKLVYNKARQAAITKELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRC_HALHL
Sequence: MDTLTLPRPDDWHLHLRDGALMQAVAPQAAAVFSRAIIMPNLQPPVTTVEQAAAYRQRILGALPAGSTFEPLMTLYLTDKTSPEEIVRAAASGFVHAVKLYPAGATTHSDAGVTDLLLCYDALAAMEEQGLPLLIHGERTGPELDIFERETAFIDDVLQPLLDRHPRLKVVLEHVTTAVGAELVTGDDPRLAGTFTPQHLLYNRNDLLVGGLKPHYYCMPILKREADREALLEAATSGHPRVFLGTDSAPHPRGAKESACGCAGCYTAPIALSLYAEAFEAAGALERLADFAGRNGPAFYGLPVNPETVTLERAPLEVPASYPGGDEPVVPLRAGESLAWRLHQP
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TATA_ALKCK
Sequence: MGGLSVGSVVLIALVALLIFGPKKLPELGKAAGSTLREFKNATKGLADDDDDTKSTNVQKEKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MUTL_XANOR
Sequence: MAIRQLPEMLINQIAAGEVVERPASVVKELVENALDAGATRVDIELEEGGVRLIRIRDNGGGIAPDELPLAVSRHATSKIASLDDLETVATLGFRGEALPSIASVSRFTLTSRRHDAEHGSALEIDGGRLGEVVPRAHAPGTTVEVRELFFNVPARRKFLRAERTELGHIEEWLRSLALARPDVELRVSHNGKPSRRYKPGDLYSDARLGETLGEDFARQALRVDHSGAGLRLHGWVAQPHYSRASTDQQYLYVNGRSVRDRSVAHAVKMAYGDVLFHGRQPAYVLFLELDPARVDVNVHPAKHEVRFREARLIHDFVYRTLQDALAHTRAGATPNSIGSDGAGYTGATAGEMGNIASGGPANHGNAPGRSGSAYSYANWTPSQTPLGLRVDEARAAYSALYAPPPRNAPQSTGMPSMAGTGLPATSEDSGVPPLGYAIAQLHGIYILAENAEGLIVVDMHAAHERIVYERLKNAHDSIGLHAQPLLVPMTLAVGEREADTAEREADTLATLGFEITRAGPQSLHVRSIPALLANAEPEALLRDVLGDLREHGQSCRIASARDELLSTMACHGAVRANRRLTVPEMNALLRDMEATERSGQCNHGRPTWARFTLSDIDRWFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: POTA_LACAC
Sequence: MDIIKLKHITKRYDDGFIALKDINITIESGKFYSLLGPSGSGKSTILRIIAGFTQPSSGQVFFDGKDITDLDASKRHINTVFQNYALFPHLNVFENVAFGLKIKKKPLNEIRPAVKDALHMVRLDGYANREISELSGGQQQRVAIARAIVNEPKVLLLDESLSALDKRLRKDMQFELRAIQKKLGITFIFVTHDQEEALSMSDEIFVLNDGQIQQSGSPVAIYDEPVNDFVARFIGDSNILPGRMIKDYVVEFANNKFRCADGGIKSNEKVEVVIRPEDLDIVAPEKGKIVVTAQTQLFLGDHFEIKAIDANENEWLIHSTNGVKLGQRIGLFFDPEDIHVMRLNESQKDFDARIEKYEGDENED
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y2785_YERPG
Sequence: MQIWVDADACPNVIKEVLFRAADRTGMMVTLVANQPLKTPPSKFIRTVQVASGFDVADNEIVQRVEKNDLVITADIPLAAEVIEKGGIALNPRGERYTPDTIRERLNMRDFMDTMRASGIQTGGPNTLNQRDRQQFANELDKWLQQARNQAK
What are the official names of this protein?
UPF0178 protein YpAngola_A2785.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: OGFD2_MOUSE
Sequence: MATAAQRRFCRCACFCSQNLYVARYGLHLRFRDEHQLRRDYGQLLRSRGCVTSKDFQQLLEELEQEVGRRRRLGQESAVRKALIASSYHPARPEVYSSLQDAALAPEFMAAAEYSTSPGADLEGLLQRLETVSEEKRIYRVPVFSAKFCQTLLEELEHFEQSDMPKGRPNTMNNHGVLMYELGLDDPLVTPLRERFLLPLMALLYPDYGGGYLDSHRAFVVKYALGQDLDLGCHYDNAELTLNVALGKDFTGGALYFGGLFQAPAALKETLEVEHVVGSGILHRGGQLHGARPLCKGERWNLVVWLRASAVRNRLCPMCCQKPELVDDEGFGDGFTREEPTTVDVCVLT
What are the official names of this protein?
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the OGFOD2 family.
Protein: RPN1_HUMAN
Sequence: MEAPAAGLFLLLLLGTWAPAPGSASSEAPPLINEDVKRTVDLSSHLAKVTAEVVLAHLGGGSTSRATSFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKSGRFFTVKLPVALDPGAKISVIVETVYTHVLHPYPTQITQSEKQFVVFEGNHYFYSPYPTKTQTMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDVPAYSQDTFKVHYENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRFVDHVFDEQVIDSLTVKIILPEGAKNIEIDSPYEISRAPDELHYTYLDTFGRPVIVAYKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIIYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETVNRYKQSRDISTLNSGKKSLETEHKALTSEIALLQSRLKTEGSDLCDRVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLISGKRQELVTKIDHILDAL
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: TRPA_PHOPR
Sequence: MDRYQELFNRLAAKNEGAFVPFVTIGDPTPEQSMKIIDTLVASGADALELGIPFSDPLADGPTIQAATIRALESGTTPIVCFELLTQIRAKYPDMPIGLLMYANLVFTAGIETFYKKCADAGVDSVLIADVPIKESEEFRVAAEKYGIHPIFIAPPNATDETLKSVSELGGGYTYLLSRAGVTGAETKAGKPIRHLVESLTKHNAPPALLGFGISEPAQVKEAIEAGAAGAISGSAVVKIIENNLSDHTAMLDNLGQFIRDMKAASKLS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TTC21_CAEEL
Sequence: MDSESDDNPNDPEDRKKWGHKDVEHWRAVSNVHYYAREGYFGTAILVCDGRLATIKDPALAILKGVCLTLLGKIPDAIRHLETFVTDNDVALGALHALKWAHASAFNPDNKSIVEIETEISTRARNEKTPYTSYATASEVLYFAGEYQKSKQMLDIARKRATEKHAKHYCLLGWIELALGKKQKSTQELFEKAGGQEYPDGNIGRCKILEGHHSAPEMKVAANELAISTIHFLPGHIEKAKASIMMKDWRGVMDCIMNADQPEGSNPYIEVLRTVHGICYAGEVSMLKRTLQLLLKSLDENEATNHVLYARITKLLVSISGRDEKILRHARDFLTRALKISRKPDYVALSMRIAFGLGGAKEVSTLSQELVALDCEDSYAVLSSVVSMLMISRVSDARAQFDILPSAHPKLLESPLYYLIASVLAKQSKDKSFENFRQHIENLVEMLRNQLQSFPFGLDYLSLFSSDLLYSAVEQCFDFYPLVPIKAPDDCMKLTAKTLQMIYDVAPGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELILDRGGKITDADDALVTGLNFNFKLRETSLYHLIKSKTFKKRNENDEAIKTLKMALQIPRKEPSKNLFQPKESADTHKISVQLELIDTLQHMKRIQEAETTMTDALAEWAGQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVEATPGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLKLANLLLKLRNFEKCEKVLRAPFERDPEPVGTETIQTYIQFLLLLAECHEMMDNVPEAMNDFEKAKSLHSRIQDKTLTAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVTESGYNVCRGRFEWYTGDQNEALRYYSRTKDSAAGWREKALYYMIDICLNPDNEIIIDENSVENPETTIVEEASEQQKLAKYYLDLLGKLPTTDRFLLAQNFIRMHTTDKSAIQAALDEFNRMAFNADRSQVTNVGAVFGVARGHVLLKQVQKAKTVLKMVNGRVWNFDDSDYLEKCWLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAFMATKERNPGFGYKLAFTYLKAKRLFACIETCQKVLDLNPQYPKIKKEIMDKAKALIRT
What is the function of this protein?
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport (PubMed:27515926, PubMed:28479320).  In particular, may act redundantly with the intraflagellar transport protein ift-43 to regulate the transport of specific ciliary cargo proteins such as che-3 which are related to motility (PubMed:28479320).  Functions in cilia biogenesis (PubMed:27515926).
What are the official names of this protein?
Tetratricopeptide repeat protein 21 homolog, TPR repeat protein 21 homolog, Intraflagellar transport protein 139 homolog.
What is the protein family that this protein belongs to?
Belongs to the TTC21 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite.
Protein: THIG_BRUME
Sequence: MLEFYGKRFESRLLLGTAQYPSPSILADAVRASLSRIVTVSLRRESGEARAGQDFWALIKALGVAVLPNTAGCHTPREAITTAHMAREVFGTNWIKLEVIGDTDTLQPDPFGLVEAARILCDEGFEVFPYMNDDLIVAERLIEAGCKVLMPWGAPIGSGRGFNNPYALKTMRAHFPDIPLVVDAGIGVPSHAAAAMELGFDAVLINTAVAKAGDPAAMARAFALAVEAGRLAYEADPIEARDMASPSTPLLGKAFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFK_AZOBR
Sequence: MSMSHPVSQSADKVIDHFTLFRQPEYKELFERKKTEFEYGPTPTKEVARVSAWTKTEEYKEKNLPVEAVVINPTKACQPIGAMLAAQGFEGTLPFVHGSQGCVSYYRTHLTRHFKEPNSAVSSSMTEDAAVFGGLNNMIDGLQRYALYKPKMIAVLTTCMAEVIGDDLSGFINNAKNKESVPADFPVPFAHTPAFVGSHIVGYDNMIKGVLTHFWGTSENFDTPKNETINLIPGFDGFAVGNNRELKRIAGLFGIQMTILSDVSDNFDTPADGEYRMYDGGTPLEATKEAVHAKATISMQEYCTPQSLQFIKREGPAGRQAYNYPMGVTGTDELLMKLAELSGKPSRGVKLERGRLVDAIADSHTHLHGKRFAVYGDPDFCLGMSKFLMELGAEPVHILSTSGSKKWEKQVQKVLDACRSASSGKAYGAKDLWHLRSLVFTDKVDYIIGNSYGKYLERDTKIPLIRLTYPIFDRHHHHRYPTWGYQGALNVLVRILDRIFEDMDANTNIVGETDYSFDLVR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: ZN473_MOUSE
Sequence: MERKEDDLKGGCWNQPAVAEEFETLKDLAMDFTVEDWKDLESEWDQRDLFWDVTLNHYQDMFSFTDTSQPSLTSQPDVREELEATSTEVPETKSSPLQSGFVEEDFSQIMEIFSNGQLNFEACIGEDWLNSFLGDPESLPRPDISDKESPADHQSPESKSGLSPGPPLCTREDAVMSASPEKTLTPVILKESRSDLSQEDSVQGHEKPYKCSECGESFSQSHHLIQHWVLHTSGEPPIWREQQRGLSQGAHFPMCPGTPASYESYTCQECGKRFSQNVYLQWHQKIHTGEKLCKTQSDSNLEGLSRSPSVEPGKQRLSKDTDSAKPSTIHGQDQEKPPTGESRDQENLHESQPGDRPSVLHPKPLRHQKTPTNAKCFRCKKCGETFSGAFHLAKHQRAHAQRLYKCASCPAVFNLSKHCFQHRKSHFPSAACECQGCRKSFNWRSSLIKHQAIHKGEKPYKCDECGKAFNHSSTLKIHQRIHSGQKPHKCSECGKAFCRRTDLTEHQRVHSGFRPHQCPVCARTFNRPSHLVRHRLRHAEERHFGCAKCKETFIYKEQLERHNKIHTIEGLYECKQCGEHFICRSTLNCHLSIHIRENTSEKVVGQNSQHTEKCFKNTKCRKAPNHSRYLGQHEKIHAQVTSGECDPCGETYDQSVQPICHQSICAGVKPSECAEPEKCTRNTSASEHHPSQREPSFKCDIYNRAFKQRAHLSKHQLIHITEKPFKCNECDRAFKQSNYLIQHQKTHTAEKHFECSECGKTFHQRSCLSKHQKIHSGEKPFKCGDCGKAFISGAQLIRHQRIHTGEKPYVCQECGKTFSQSSCLTLHLRIHTGEKPYTCGTCGKAFAQRANQRKHERIHTGEKPYACGLCGKAFGLRTHLQQHQRIHTKAKP
What is the function of this protein?
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex.  Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed.  Required for cell cycle progression from G1 to S phases (By similarity).
What are the official names of this protein?
Zinc finger protein 473 homolog, Zinc finger protein 100, Zfp-100.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA (By similarity).