PharMolix/UniProtQA huggingface dataset:
Protein: PTN3_HUMAN
Sequence: MTSRLRALGGRINNIRTSELPKEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS
What is the function of this protein?
May act at junctions between the membrane and the cytoskeleton.  Possesses tyrosine phosphatase activity.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 3, Protein-tyrosine phosphatase H1, PTP-H1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: UREE_PROMH
Sequence: MKKFTQIIDQQKALELTSTEKPKLTLCLTMDERTKSRLKVALSDGQEAGLFLPRGTVLKEGDILLSEEGDVVTIEAAKEQVSTVYSDDPLLLARVCYHLGNRHVPLQIEAGWCRYFHDHVLDDMARGLGATVVVGLEKYQPEPGAYGGSSGGHHHHHDHHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.  It is not essential for urease activity.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35U4_HUMAN
Sequence: MADDKDSLPKLKDLAFLKNQLESLQRRVEDEVNSGVGQDGSLLSSPFLKGFLAGYVVAKLRASAVLGFAVGTCTGIYAAQAYAVPNVEKTLRDYLQLLRKGPD
What are the official names of this protein?
SLC35A4 upstream open reading frame protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: T161A_XENLA
Sequence: MAVMGIQMVVTLLVASLMQRVSPHYSFGRWLLCNGSLFRYKHPTEEELRTLAGKQKPKAKKERRTNGVAEEKPLTVPKDIDLRLDTQPINTMDALVLRYFLEYQWFIDFALYSTIIYLFTEAYYCVVDAQNEINIGVLWCLMSIIFSIKVLFTVMKHYFRSEEGGERSVCMTFAFFFLLIAMIVTIVRDEYLEFGLEPGLASVCHNLENFLAQQGWQWSMPFVKLAFKIALVALCAFLGGCLTFPGLRLAQTHLDALKMAADRPMLQLLLHMSFLPPVIVVVLWIRPITRDFLLNAPMGKESVELMSNSAYNTFRLWIIVLLCLLRFCLTRFHLQAYLCLADRWVEQMKREAGRISMLEIQRKISRIFCYLTVVALQYLAPVILTFHCVFMLKSLGDYSWGLYPEPPGFSPVVDSSPVQSHSPTSEEEEDTEDVQAAVEQIMGVLTSLRGLFTPLFFRGIFSFLTWWVSVCQIITSLFGLYFHQYLGAS
What is the function of this protein?
May play a role in protection against oxidative stress.
What are the official names of this protein?
Transmembrane protein 161A.
What is the protein family that this protein belongs to?
Belongs to the TMEM161 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACPS_BRUA1
Sequence: MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVNTPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S22A6_MOUSE
Sequence: MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLDKQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL
What is the function of this protein?
Involved in the renal elimination of endogenous and exogenous organic anions.  Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc).  Mediates the transport of prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) and may be involved in their renal excretion (By similarity).  May contribute to the transport of organic compounds in testes across the blood-testis-barrier (By similarity).  Also mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate (By similarity).  Mediates the sodium-independent uptake of p-aminohippurate (PAH).  PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity).  PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid and PKC activators.
What are the official names of this protein?
Solute carrier family 22 member 6, Kidney-specific transport protein, Novel kidney transcript, mNKT, Organic anion transporter 1, Renal organic anion transporter 1, mROAT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: EIF3L_ASPTN
Sequence: MSYEERANAHPNLNDESDVEEEALVNDYREQVNFDDGMSELDRTTSLGAASQTQDLQAQLAAAATPLEYQATLETKFASYDNYCSLFHYILNSDGPVELEVPSYYWAWDVIDEFIYQFESFCRYRNRVARSGSNEEEAQLLRENPNTWGCYSVLNVLYSLIQRSQINEQLAAMKRGEDPLAFAGEYGSRPLYKMLGYFSIIGLLRVHCLLGDFSLALKTLDDIEMNKKAMFARVMAAHFTTYYYVGFSYMMMRRYGDAIRMFSHILVYVSRTKNFQKGGNSYDAIAKKNDQMYALIAICVALHPTRLDDTIHSALREKYGEQLNRLQHGGPEALPLFEELFRSACPKFISPTPPDFDNPSVNIDPVDHHTAIFMDEVKNTLYNPTIRSYLKLYTTMDLKKLAGFLEVEPEKLRSWLLVNKQRSRQVRWVEGGLLEGEPVNANDLDYALEKDLIHVSETKAGRRLVDWYLRNLARVY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_RALPJ
Sequence: MAKNKFNQSWLHDHINDPYVKLAQREGYRARAAYKLKEIDEQDKLIKPGQVIVDLGAAPGSWSQYVRNKLAASPRAKDGRIDGAIVAIDILPMEAIADVTFIQGDFREDEVFRQLEEIVLEVSGGGKVDLVLSDMAPNLSGVASADAARMEHIAELAVEFAMAHLKPEGALLIKCFHGSGYSQIVEMFKRHFKIVAPRKPKASRDKSSETFLLGRQLKHPG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_TRIV2
Sequence: MAYAIIETGGKQVRVEPGRFYDIELLSAEPDEKVTIESVLLVQNDGEVTIGQPLVAGATVQGTVLRHLRGRKVLVYKMKPKKKTRKKRGHRQEITRLLIDSITFNGTVLTAPTASAETADATPDTETAAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GIP2_PHYSO
Sequence: MKVTATIAAASMAIAAASADADTTSRQLILGGSIIPSGQKTYSVGIRSTAGGDTYCGGALISPTHVLTTTMCTKHAKPDFVAVGTHYVNGTKDGEQLKVIQAQNHTDFNKTGNGEYDFALLTLEKPSKFAPVKLPKADDSDIKPGMWSKAMGWGWTSFPNGSPSNEMQGVNLQVWSNEDCSQVYVINPTNVCAGGVAGKDACVADTGGPLIKENGAGDKDDVLIGLVNWGYGCGDEGAPTVYSRVSSALKWVNPIIKTKQVKTAVPVQQAISGKHGVPIKQGMPGTVRN
What is the function of this protein?
Secreted effector that suppresses host plant glucan elicitor-mediated defense responses (Probable).  Targets host endoglucanases and inhibits the endoglucanase-mediated release of elicitor-active glucan oligosaccharides from P. sojae cell walls (Probable).
What are the official names of this protein?
Glucanase inhibitor protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSH1A_ORYSJ
Sequence: MAVASRLAVARVAPDGGAAGRRRRRGRPVVAVPTAGRGRGGAVAASPPTEEAVQMTEPLTKEDLVAYLVSGCKPKENWRIGTEHEKFGFEVDTLRPIKYDQIRDILNGLAERFDWDKIVEENNVIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVGEEMGIGFLGIGFQPKWALSDIPIMPKGRYEIMRNYMPKVGSLGLDMMFRTCTVQVNLDFSSEQDMIRKFRTGLALQPIATAIFANSPFKEGKPNGYLSLRSHIWTDTDNNRSGMLPFVFDDSFGFERYVDYALDIPMYFVYRNKKYIDCTGMSFRDFMVGKLPQAPGELPTLNDWENHLTTIFPEVRLKRYLEMRGADGGPWRRLCALPVFWVGLLYDEESLQSISDMTSDWTNEEREMLRRKVPVTGLKTPFRDGYVRDLAEEILQLSKNGLERRGYKEVGFLREVDAVISSGVTPAERLLNLYETKWQRSVDPVFQELLY
What are the official names of this protein?
Glutamate--cysteine ligase A, chloroplastic, Gamma-ECS A, GCS A, Gamma-glutamylcysteine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y898_BRASB
Sequence: MTQHPPGDDRTNRIVAVTLDEESIGRSGPDIEHERAIAIYDLVEENLFAPEGADGQGPFTLHLGITANRLMFDIRKEDGTPVVTHLLSLSPFRRIVKDYFMICDSYYNAIRTATPDKIEAIDMGRRGIHDEGSRTLQERLKGKVRVDFETSRRLFTLITVLHWKGEGQ
What are the official names of this protein?
UPF0262 protein BBta_0898.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: RS16_HALOH
Sequence: MAVKIRLRRMGSKRNAHYRLVVADSRKPRDGRFVEEIGYYNPTTEPATVKVDEEKAIKWLKNGAQPSNTVRSLLKKTGVLAKFREQQQ
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: UXAB_ECOLC
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKAKGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: RL14_BACC1
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RIMK_SALEP
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: IFNL1_HUMAN
Sequence: MAAAWTVVLVTLVLGLAVAGPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNLCLRTSTHPEST
What is the function of this protein?
Cytokine with antiviral, antitumour and immunomodulatory activities.  Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.  Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state.  Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1.  Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
What are the official names of this protein?
Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, Interleukin-29, IL-29.
What is the protein family that this protein belongs to?
Belongs to the lambda interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERR1_CANLF
Sequence: MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGSFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAVLLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD
What is the function of this protein?
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'.  Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter.  May function as a modulator of the estrogen signaling pathway in the uterus.  Induces the expression of PERM1 in the skeletal muscle (By similarity).
What are the official names of this protein?
Steroid hormone receptor ERR1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Co-localizes to the cytoplasm only in presence of MAPK15.
Protein: NAPA_SALTI
Sequence: MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTALKEKGPEAIGMFGSGQWTIWEGYAAAKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYIIQNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVAEYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPAGTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFSRRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLAKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RSSA_OSTLU
Sequence: MAPQMSQKEADIAMMLAAGCHLGTKNVDFQMERYVWKRRADGIHIINLGRTWDKLMLAARIIVACENPQDVICQAARPYGQRAVLKFAQYTGAKAIAGRHTPGTYTNQKDAIFAEPRVLIVTDPRTDAQPISETAYVNLPTIAFCDTDSPLKNVDVAIPANNKAKHSIGCLYYLLARMVLQMRGTVSAANPWDVMVDLFFYRDPEELEAKEEEAAAAAAAPAESAGYNAVADAAYGAESWDEQKPAEAFPTGGFAPAAGNWSEAPAPTGWDAQQGGDFGSGFGAMPPQGY
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPM7_HUMAN
Sequence: MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
What is the function of this protein?
Essential ion channel and serine/threonine-protein kinase.  Divalent cation channel permeable to calcium and magnesium (PubMed:35561741).  Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death.  Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx.  The kinase activity is essential for the channel function.  May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell.  Phosphorylates annexin A1 (ANXA1).
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, LTrpC-7, LTrpC7.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM7 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPA_SHISS
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPIEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISTPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKVATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: OGG1_PICTO
Sequence: MISSDYIKDKILEIENIQGNLIRSRISEFKRLKKSDKYTLFKELSFCILTANTSAELGLKCQAYINDGFYRLDYNDLREELIKVHYRFYNKRASYIIGARDIIDDLEYIVNMDDHFRAREILIERVKGIGYKEASHFLRNVGVFDFAILDKHIIKFMKNNYYIKYENNSSRRRYLENEIVFNELAKKFNMEPGVFDLYIWYIETGKILK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: SYH_CLOK1
Sequence: MAIQAPKGTKDILPTESYKWHYLEDKFKNIADSYGYREIRTPVFEYTELFQRGVGETTDVVQKEMYTFLDRAGRSLTLKPEGTSPAVRAFVEGSLYNEAQPTKLFYFTPVLRYENVQKGRLREHHQFGIEAFGSREASLDAEVISLAMRIYEELGVDGIELNINSIGCSKCRKEYNDILKTFLSKQYDNICDTCKTRFHKNPMRILDCKEKSCREIVKDAPLMLHHLCDECREHFESLKMYLEGLGIGYKINPLIVRGLDYYSKTVFEIINKNITICGGGRYDYLIEEVGGPKMPAVGFGMGIERTLLTLSENGIEIPKLPYIDLYIGIIGDKARIKALTLTNKLREKNVRCEYDHMNRSVKAEMKYANKINARFTVILGENEIESGIAKFKRMEDGQQFEISLGDLSAILNLTRM
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_SALNS
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.