PharMolix/UniProtQA huggingface dataset:
Protein: TTCA_PSYA2
Sequence: MTAATLFTQQTTPQFDKASIDTDVNHHAKTTAIEAMLYDDSDDRNDDFMDEQADKILADTQSLTESAYFRKLQKKLRRQVSWAIRDFNMIEDGDVVMVCVSGGKDSYTLLDILLLLKRIAPIHFDIVAVNLDQKQPGYPEEVLPAYLNEQGIAHYILEKDTYSIVKSVVPEGKTYCSACSRLRRGSLYGFAKQIGATKIALGHHRDDMLATFFLNLFHGGALKSMPPKLLSDDKQNMLIRPLAYVEEKDIIEYARLKEFPIIPCNLCGSQTNLQRAIINDMLREWDDAHPQRLASIFKAMQNVAPSQLADRELFDFETLSLERDDNERLFEGDNIQAGQIESLAEIGLPVAPATQIFNPNFVDTEKGSHTPKKIPTINPVI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHJ_SPIOL
Sequence: MQGRLSAWLVKHGLVHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIEYGVDQPEEVCIKVFAPRRNPRIPSVFWVWKSADFQERESYDMFGISYDNHPRLKRILMPESWIGWPLRKDYIVPNFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL31_RUEST
Sequence: MKKDIHPDYHFIDVKMTDGTVVKMRSTWGNEGDQLALDIDPSAHPAWTGGSSRLMDTGGRVSKFKKKYEGLGF
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: Y169_METJA
Sequence: MIFMIITIASGKGGVGKTTTSASLAVALAKLGKKVLAIDGDISMANLGILFNMEKKKPSLHEVLSEEADVRDAIYKHKTGVYVLPTSLSLEGYKKSDIDLLPDVVNEVADDFDYVIIDAPAGLNREMATHLAIADKLLLVVTPEMFSIIDAVRLKESAEMAGTPLMGVVLNRVGRDFGEMGRDEIEMLIKGKVLVEVPEDENVRSAALKKMSVIEYRKNSPASQAYMKLASIIAGVPIYIEDEIKIIRKESFIDKIKRLFRMY
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0169.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
Protein: AZUR1_METJ
Sequence: MKSSKIVAILLASLFSGSVLAAGCSVDVEANDAMQYNTKNIDVEKSCKEFTVNLKHTGSLPKNVMGHNLVITKTADFKAVMNDGVAAGEAGNFVKAGDARVVAHTKLVGGGEKDSVKVDVSKLAAGEKYTFFCSFPGHATMMRGTVTVK
What is the function of this protein?
This methylothroph organism uses azurin in the electron transport chain involved in methylamine/methanol oxidation.
What are the official names of this protein?
Azurin iso-1.
What are the subcellular locations of this protein?
Periplasm.
Protein: ODPA_SCHPO
Sequence: MFRTCTKIGTVPKVLVNQKGLIDGLRRVTTDATTSRANPAHVPEEHDKPFPVKLDDSVFEGYKIDVPSTEIEVTKGELLGLYEKMVTIRRLELACDALYKAKKIRGFCHLSIGQEAVAAGIEGAITLDDSIITSYRCHGFAYTRGLSIRSIIGELMGRQCGASKGKGGSMHIFAKNFYGGNGIVGAQIPLGAGIGFAQKYLEKPTTTFALYGDGASNQGQAFEAFNMAKLWGLPVIFACENNKYGMGTSAERSSAMTEFYKRGQYIPGLLVNGMDVLAVLQASKFAKKYTVENSQPLLMEFVTYRYGGHSMSDPGTTYRSREEVQKVRAARDPIEGLKKHIMEWGVANANELKNIEKRIRGMVDEEVRIAEESPFPDPIEESLFSDVYVAGTEPAYARGRNSLEYHQYK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KHSE_RHIME
Sequence: MAVYTDITEDELIRFLAAYEVGSLTSYKGIAEGVENSNFLLHTTKGAYILTLYEKRVNADDLPFFLGLMHHLAERGLSCPLPLPRADGKLLGTLSGRPAAVISFLEGMWLRKPEAQHCREVGRALASMHQAGEGFPLKRPNALSVEGWRPLWRNSEARADEVQAGLKDEIATELAFIEEHWPKDLPEGVIHADLFPDNVFFLGDRLSGLIDFYFACNDFLAYDVAICLNSWCFEKDGSYNITKGMALLSGYESVRRLTAEEIEALPLLARGSALRFFLTRLYDWLMTPPGALVVKKDPLEYLTKIRFHRAIVSSAEYGLRREEAPA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: FND1_PINMG
Sequence: MKSWISISFLCMLFPLSNGQLGSSGQVTLQGAQISQATQSLQGTAPTSQYPQGGTQISQGGAQATQNYQGVAQGTQISQGLTQGAQISQGGGQGISQGATQGTQFSQGTVPSGQFFQNIVQGTQAVLSGAQHSQAGAQGSQFPQSAAHTAQHHQGTAQPAQSGTHAILKEMEKSLAEFKAYVEYLENMVYKERMKYPSPYIQNFTASPSNFTYTTFENDVDMRLSSMERISSELVKQMVNCPRGPVPPPPPQSVMVQSDTVDNSSNIYVSWDPPYFEGKPLTGENMHYKVYFSPSDQYGKATGGEFIFRICDANFTQASVTDLNPRSFYSIQVAATLCEAIESEGTSTSVKTPDLIPSAPLNLKLEGTKPNAFAVSWDPPTVKGTLTNYTIYATEESGKATMVTIDPKLTSYALYNLYEGTMYTIRIAASSDNGMSPKSEPLEVTTDKFIPMAPRNVRAIDNNLTSVTLEWDAPLPGRGMIRGYRINYTLDFTDYEEMLISDPSITTATITNLTPATEYYFQVFARTMKRLGYGSHLIMNKTKMDVPSEPMSVVHRIMDNGLQRIQVSWQPPENTYGPIIDYIIHWGVRGGATRKEFLTPYVLSWTSDFLDDNANHDFKLFAQNVVGIGKPVAFSVKTLPKPQILVPNVRVKRETSKNNITSLTVTWGSPKVPVDGFFVLYRKYEGVYSDRWKFIEIPKPNARGTTITVTQENVPYVVVCKGFKRQKKPTSNLSSQQFSFPGQQVGQQQSNPWI
What are the official names of this protein?
Fibronectin type III domain-containing protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: PEBP1_MOUSE
Sequence: MAADISQWAGPLCLQEVDEPPQHALRVDYAGVTVDELGKVLTPTQVMNRPSSISWDGLDPGKLYTLVLTDPDAPSRKDPKFREWHHFLVVNMKGNDISSGTVLSDYVGSGPPSGTGLHRYVWLVYEQEQPLSCDEPILSNKSGDNRGKFKVETFRKKYNLGAPVAGTCYQAEWDDYVPKLYEQLSGK
What is the function of this protein?
HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system.  HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.  Seems to be mediated by a specific receptor (By similarity).
What are the official names of this protein?
Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAVE_LEGPH
Sequence: MTRFIMLSFVTGYRKSISCNRFSRNVVSPYFFMRTIIMTRFERNFLINSLMFLETILSVDKKLDDAIHHFTQGQYENPRYQINSRITNADDWSKEDKLKFTSAIAEAIALVSEKYENPTSETTEQIQSARNILLDNYVPLLTANTDPENRLKSVRENSSQIRKELIAKLKDEVPYKSQFENPYVLFPFVAATVAVAATAASVLFGNKP
What is the function of this protein?
Virulence effector that is indispensable for endoplasmic reticulum (ER)-mediated remodeling of the Legionella pneumophila-containing vacuole (LCV) and lysosomal evasion (PubMed:33563829).  Essential for intracellular replication in human monocyte-derived macrophages (hMDMs) and amoebae, as well as for intrapulmonary proliferation in mice (PubMed:33563829).
What are the official names of this protein?
Effector protein MavE.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Single-pass membrane protein. Note=Translocated into the host cell via the type IV secretion system (T4SS) (Probable). During infection, localizes to the poles of the LCV membrane (PubMed:33563829).
Protein: AROE_AFIC5
Sequence: MSETPTACLIGWPAAHSRSPIIHKYWLKELGIAGDYRIEAVEPAAFPDFIASLAARGYCGANVTIPHKEKALALSLPDARARAVGAANTLYFRDDKLHSTNTDVEGFIGNLDASAQRWRADDDAVVLGAGGSARAVVFGLIERGVPRIHLVNRSRERAQALAQPYGERVSVASWDDVESLLPKAGLVVNTTSLGMKGQPPLPLDVALLRADATVADLVYVPLRTELLTAAAGRGLQTADGLGMLLHQAVRGFELWFGRRPQVSPALRALVEADLTVK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: F16PA_XANOR
Sequence: MSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGALGGVLGDAGTGNVQGEAQKKLDVLSNDILLEANAWGGHLAACASEEMDHSQPVPEQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEHFLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPDETAEYAINMSNQRHWEPAMQAYVGDLLAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQPTQLHQRVPVFLGSKNEVAAATRYHLDADKA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMB_ECOLI
Sequence: MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEPEALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKGQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK
What is the function of this protein?
Catalyzes the reversible hydration of fumarate to (S)-malate.  Functions in the generation of fumarate for use as an anaerobic electron acceptor.  To a lesser extent, also displays D-tartrate dehydratase activity, but is not able to convert (R)-malate, L-tartrate or meso-tartrate.  Is required for anaerobic growth on D-tartrate.
What are the official names of this protein?
Fumarate hydratase class I, anaerobic, D-tartrate dehydratase, Fumarase B.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: SWM1_YEAST
Sequence: MSSSSYRDSYFQYRHLPAPHHILYAEWNQDILALPDEVANITMAMKDNTRTDAEEGRAPQDGERNSNVRESAQGKALMTSEQNSNRYWNSFHDEDDWNLFNGMELESNGVVTFAGQAFDHSLNGGTNSRNDGANEPRKETITGSIFDRRITQLAYARNNGWHELALPQSR
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.  In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition.  In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.  SWM1 is required for APC/C activity in meiosis.
What are the official names of this protein?
Anaphase-promoting complex subunit SWM1, Anaphase-promoting complex subunit 13, Spore wall maturation protein 1.
What is the protein family that this protein belongs to?
Belongs to the APC13 family.
Protein: SMRCD_XENTR
Sequence: MSAFNLERFRFDKGKKIDTEFGEKGASSRPSTPNSQLEDHVTSIPETPEAKRVNNPSLFKKDKGVSFLDSDSENEDHQSKSKFSSTHQQSHPREENGTSDSVTDDSEDDYLAVKRPSASTAQVKDGSKYKNLQRLKEIFPKQNNDELLKLIESTSTLDGAVAAGVVLFNKEGSSRKRKLDEVPKDSSPVHEGINGQTKKKKKIDRVSSDNDSSLSEDDWEKQEASVKKLQRHFPDLDKEELREVLQEHDWSFHEALEALKLFAEDETDALQNAAKKEVSNGKEFSRSNKNDNKSSAKAKANQNSNKAMAQNGVKKKGKGKKYSENAKRDTRDLESEESASDAGSCLDEDYSSGDEKLEEEYKTKILSFLQDASLDELYLIPHCSHKKAQKITELRPFSSWESLFEKMTKSNGLSEDLIWDCQTLIKEREVVMKLMNKCEEISRTLTKQVTQLTEDGECGWNIEQPSIMSENLVLKPYQKIGLNWLALLHKHKVNMILADEMGLGKTVQAIAFLAHLYVTGDSGPHLVVVPASTMDNWIREFNQWCPSMNILLYYGSQEERKHLRYDILNKVVEFNVIVTTYNCAISSAEDRSLFRRLKLNFAVFDEGHMLKNMSAIRYQHLMTLNARSRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIKRLFSSKAKSTDEQTIFEKERIAHAKQIMKPFILRRVKSEVLKQLPPKQDKIKFCQMSKKQEQLYSDLLNKLKKSIDATEKNSELCNVMMHLRKMANHPLLHRQYYTADRLRTMSKLMLKEPTHCDANPDLIFEDMEVMTDFELHRLCNEFTTLSQYKLEKELILDSGKFNILEKLLSDIKKKGDRVVLFSQFTMMLDIIEVFLRHHQHRYVRLDGKTQISERIHLIDEFNTDMDIFIFLLSTKAGGLGINLTSANIVILHDIDCNPYNDKQAEDRCHRVGQTKEVKVIKLIGKGTIEESMLKISQQKLRLEQDMTTNDTGDEGTIPLDMATLLKTSLGL
What is the function of this protein?
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization.  Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.  Required for the restoration of heterochromatin organization after replication (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with PCNA at replication forks during S phase. Recruited to double-strand breaks (DSBs) sites of DNA damage (By similarity).
Protein: SRFAD_BACSU
Sequence: MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIFAILNQHPIIQP
What is the function of this protein?
Probable thioesterase involved in the biosynthesis of surfactin.
What are the official names of this protein?
Surfactin synthase thioesterase subunit, Cold shock protein CSI16.
What is the protein family that this protein belongs to?
Belongs to the thioesterase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASB2_RAT
Sequence: MSTEISTRGRQRAIGHEEYSLYSSLSEEELVQMAIEQSLADKTRGPTPAETSVSSQTNHQPGHIHPWTRSSSPPESPPARAPLGLFQGVMQKYSSNLFKTSQMAAMDPVLKAIKEGDEEALKAMIQDGKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGNYRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARFDVNTPLAPERARLYEDRRTSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPAPRSGRFNDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ
What is the function of this protein?
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Mediates Notch-induced ubiquitination and degradation of substrates including E2A and JAK2 (By similarity).  Required during embryonic heart development for complete heart looping (By similarity).  Required for cardiomyocyte differentiation (By similarity).  Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA (By similarity).  Also targets DES for proteasomal degradation (By similarity).  Acts as a negative regulator of skeletal muscle mass (By similarity).
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 2, ASB-2.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to the Z line in cardiomyocytes.
Protein: PLEUR_PLEOS
Sequence: VRPYLVAF
What is the function of this protein?
Antifungal activity.  Inhibits mycelial growth of F. oxysporum, M. oxysporum and P. piricola.  Inhibits cell-free translation with an IC(50) of 28 uM.  Antiproliferative activity against MBL2 and L1210 tumor cell lines in vitro.
What are the official names of this protein?
Pleurostatin.
Protein: DEF2_RALSO
Sequence: MIRPILKMGDSRLLRVAKPVQRFQTPELTALIEDMFDTMDAARGAGLAAPQIGVDLQVVIFGFDRNDRYPDAPAVPKTVLINPTIEPLSDAMEDGWEGCLSVPGLRGVVPRYTRLRYTGYDQHGHAIDRIAEGFHARVVQHECDHLQGILYPMRVQDFTRFGFTEILFPELPAHHND
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TPPC4_DICDI
Sequence: MTINSIYILNKAGTLIYQNDFGNTEKLSHNSYIRLGSTFHSLHAIASNLSPVSGSSSGIEVIETEAFKLQCFQTHTGIKFYVIADPNHQQLEELLHGVYELYTDYVLKNPFYEIEMQIRCDLFDYKLNRLLGVRE
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Endoplasmic reticulum.
Protein: NAGZ_XANOR
Sequence: MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFGSRSQVAELSAAIRAAAPRPVLICVDQEGGRVQRFREGFSALAPLQSFGAQYAQAPEAALAAARAHAQLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDDPQIVATFTRAYVQALHGAGMAATLKHFPGHGTVLEDTHVDHASDPRPLEALQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGFRGVVFSDDIGMAASLSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRRLNTAALIGLIGRGALGWDGLLAGTDASFTAPLSAHFGTTA
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_HISS2
Sequence: MLIPIPALNDNYIWVYKRENLSVIVIDIPEIAALSQFIQAQNLVIGALLITHNHRDHIGALAEFKQFYPHVHIYGPAECADQGVTQVIDAGRLIIDEYHIDVLPTGGHTAQHLSFLVDGHLFCGDTLFSAGCGRVFTGDYSQMFTSLQLLKSLPDETIVCPAHEYTLGNLAFALTTGKNKSAVQKQLEKVKKLRAENNPSLPTTLALEKQINPFLQVEGLEEFIELRKAKDMF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CATA3_ORYSJ
Sequence: MDPYKHRPSSSFNGPLWSTNSGAPVWNNNNSLTVGSRGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDITHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAIKFYTREGNWDLVGNNFPVFFIRDGMKFPDMVHSLKPNPKSHVQENWRILDFFSHHPESLHMFTFLFDDIGIPADYRHMDGSGVNTYTLVNRAGKSHYVKFHWKPTCGVKSLLDDEAVTVGGTNHSHATQDLYDSIAAGNFPEWKLFIQTIDPDHEDRFDFDPLDVTKTWPEDIVPLQPVGRMVLNRNIDNFFSENEQLAFCPGIIVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLLLPPNAPKCAHHNNHYDGFMNFMHRDEEVDYFPSRYDPAKHAPRYPIPSATLTGRREKVVIAKENNFKQPGERYRSWDPARQDRFIKRWIDALSDPRLTHEIRSIWLSYWSQADRSLGQKLASRLSAKPSM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.  Responsible for the redox homeostasis in leaves.  Prevents nitric oxide (NO) accumulation and subsequent NO-mediated leaf cell death as well as the S-nitrosylation of specific proteins (e. g.  glyceraldehyde 3-phosphate dehydrogenase and thioredoxin) by degrading H(2)O(2) (PubMed:22106097, PubMed:23331502).  Involved in photorespiration.  Promotes drought stress tolerance and recovery (Ref. 13).  Involved in NO-mediated enhanced tolerance to zinc oxide nanoparticles (ZnO NPs)-induced phytotoxicity (PubMed:25958266).  Participates in melatonin-mediated detoxification (PubMed:25912474).
What are the official names of this protein?
Catalase isozyme C, CAT-C, OsCatC, Protein NITRIC OXIDE EXCESS 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome. Cell membrane.
Protein: CTL2B_MOUSE
Sequence: MMSAAPSPDPSLDNEWKEWKTTFAKAYSLDEERHRRLMWEENKKKIEAHNADYERGKTSFYMGLNQFSDLTPEEFRTNCCGSSMCRGEMAPDLPEYEDLGKNSYLTPGRAQPE
What is the function of this protein?
Not known, expressed in activated T-cell.
What are the official names of this protein?
Protein CTLA-2-beta, Cytotoxic T-lymphocyte-associated protein 2-beta.
What is the protein family that this protein belongs to?
To the propeptide regions of cysteine proteases.
Protein: SEPT3_HUMAN
Sequence: MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATPCPTAE
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in cytokinesis (Potential).
What are the official names of this protein?
Neuronal-specific septin-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Synapse.
Protein: RRG9_TALMQ
Sequence: MAVCAASRRLTLSNVLQGVYRTELVRQHAENSAINFYAQRLTRPALTAANSNPWLSKRSFSTSQAFKDGGNIVIYDVIATKAPDGDVLTELTSTKAEDSPKTPKSPKSSSEKPKSSKTKTKAAKKSGTKYLASELVNPEKKVKRPHWQTQKEALEKKFTEGWHPRKKLPPDSLDTIRHLHATKPDVWTTPVLADQFKISPEAIRRILKSKWQPTEEERERREERWAERYKKIYSHMEELGLRRRKGEWTAKVSDARRLGLEGKSIRQNFRRKPQARPEGTEINISRPDREASPKESTSLE
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PGAM5_DROYA
Sequence: MRKLTSFVCGTGAGFAAYYLQRLRDPQAAVHNSWTNSDKPVDPWALWDTNWDCREPRALVRPLRNSQPEEENRYNAELEKAKAKKARHIILVRHGEYLDVGDSDDTHHLTDRGRKQAEFTGKRLSELGIKWDKIVASTMVRAQETSDIILKQIEFEKEKVVNCAFLREGAPIPPQPPVGHWKPEASQFLRDGSRIEAAFRRYFHRAYPDQEKESYTLIVGHGNVIRYFVCRALQFPAEGWLRISINHASITWLTISPSGNVSIKYLGDSGFMPPELLTNRIPRDVKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.