PharMolix/UniProtQA huggingface dataset:
Protein: CYB_SORHY
Sequence: MTNLRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGVCLVVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHIGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPLASLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CCL15_HUMAN
Sequence: MKVSVAALSCLMLVAVLGSQAQFTNDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI
What is the function of this protein?
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells.  Acts mainly via CC chemokine receptor CCR1.  Also binds to CCR3.  CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15.
What are the official names of this protein?
C-C motif chemokine 15, Chemokine CC-2, HCC-2, Leukotactin-1, LKN-1, MIP-1 delta, Macrophage inflammatory protein 5, MIP-5, Mrp-2b, NCC-3, Small-inducible cytokine A15.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_CITBB
Sequence: MRNIKLIIEYDGTAYCGWQVQPNGRTVQEVLQEALAAMLGEKTPLHGSGRTDAGVHARGMVACFKTDKAMPLRAFREGLNCLLPGDIAVREACEVPLEFHPRFDAHAKHYRYTILLDDLRSPLSRLTVWRLKGKLDIQAMRAACAAFVGEHDFAAFRASNCAAKTTVRRIYSMDLVQEGCLLHLDVKGSGFLKNMVRIITGTLIEVGQGKKSVEDVARLLQGGDRQQNSGMTVPPQGLCLMQVYYQEKCD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DNAC_BUCBP
Sequence: MKNHIKFLKRLKCIVPKHIKPKFHNDEELLAWNQEQGRLSSEAILRKNKAMKMQRILGRSGIRELYMNCSFENYHIEHEGHKKVVIASKEYAHNFNKNMASFIFSGKPGTGKNHLASAIGNYLILNGKSVLIVTVADLMSNIKSTFNGNNNVTEERLLNNLSNVDLLMIDEIGMQIESRYEKVIINQIVDRRSSSKRSTGMLSNLDYRGLKILLGERVIDRMRLGNSLWLTFNWDSYRKKIHGNEF
What is the function of this protein?
This protein is required for chromosomal replication.  It forms, in concert with DnaB protein and other prepriming proteins DnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity).
What are the official names of this protein?
DNA replication protein DnaC.
What is the protein family that this protein belongs to?
Belongs to the DnaC family.
Protein: CCA_BACC7
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGKMVDLFAGQEAIQKREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKALKELVETKLFSHLPYLQMSEEKLLKATQYKWDSFEADIEAWAFFLYCIGEEHPAVFLRQWKFSNKKIKDIVAVLLTIRKRKEKDWDTVFLYKTGIHIAEMAERVYEAMIESYDHTAVNRVQTLFQALPIKNRQEMNVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: EFP_ECO81
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP1S_HUMAN
Sequence: MAAVAGSGAAAAPSSLLLVVGSEFGSPGLLTYVLEELERGIRSWDVDPGVCNLDEQLKVFVSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGPCLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAPAVPGLQGALRLQLRLNPPAQLPNSEGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGRPCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPGLNSLLRRKLAERSEVAAGGGSWDDRLRRLISPNLGVVFFNACEAASRLARGEDEAELALSLLAQLGITPLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIPTFDSVAMHTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKVEF
What is the function of this protein?
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD).  Plays a role in anchoring the microtubule organizing center to the centrosomes.  Binds to DNA.  Plays a role in apoptosis.  Involved in the formation of microtubule bundles (By similarity).
What are the official names of this protein?
Microtubule-associated protein 1S, MAP-1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, VCY2-interacting protein 1, VCY2IP-1.
What is the protein family that this protein belongs to?
Belongs to the MAP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Detected in filopodia-like protrusions and synapses (By similarity). Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules.
Protein: CBBR_RHORU
Sequence: MIRHAPRHLRQMQIFDAVARHLSFSNAARELGLTQPAVSLQIKQIEALAGLPLFEQMGRVLLLTQAGTILLGHVRTILAAVTDADKAMDALKGKRAGALRIGVVSTAKYFAPRLLSVFTAGYPGVELGLTVANREQILGMIQENALDLFIMGRPPTEPAVRAELAPNPMVMVAASDHLVRRKLTFHDLSGETFLMREPGSGTRILMEKLMTDHGVLPHRMIEMSSNETIKQAVMAGMGISLLSRNTMSLELSVGRLVILDVEGLPIQRDWYVVIREGKHLAPVAEAMVAFLKAAARTC
What is the function of this protein?
Transcriptional activator for the cbb operon for RuBisCO and other Calvin cycle genes.
What are the official names of this protein?
HTH-type transcriptional regulator CbbR, RuBisCO operon transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: CH10_GLAP5
Sequence: MKIRPLHDKVILKREEIETKSAGGIVLTGSAATKSTRGTVIAVGNGRTLDNGTVLPLNVKVGDVVIFNEYGVKEEKIDGETVLILSEDNILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMTK3_HUMAN
Sequence: MPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPAGPVEN
What is the function of this protein?
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation.  May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804).  Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase LMTK3, Lemur tyrosine kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Cell projection, axon. Cell projection, dendrite. Golgi apparatus membrane. Note=Punctate pattern in cell projections.
Protein: PURA_STAES
Sequence: MSSIVVVGTQWGDEGKGKITDFLAEQADVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGISTDNLRISNRAQVILPYHLAQDEYEERRRGDNKIGTTKKGIGPAYVDKAQRIGIRMADLLEKETFERRLKENIEYKNACFKGMFNETCPTFDEIFDEYYAAGQRLKDYVTDTAKILDDANVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPVAGNVTVGTGVGPTSVSKVIGVCKSYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGEKITEYPANLDQLRRCKPIFEELPGWTEDITGCRSLDELPENARNYLERISELCGVHISIFSVGPDREQTNLLEQLW
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUCI_VARHI
Sequence: MKIIILSVILAYCVTDNCQDACPVEAEPPSSTPTVPTSCEAKEGECIDTRCATCKRDILSDGLCENKPGKTCCRMCQYVIECRVEAAGYFRTFYGKRFNFQEPGKYVLARGTKGGDWSVTLTMENLDGQKGAVLTKTTLEVAGDVIDITQATADPITVNGGADPVIANPFTIGEVTIAVVEIPGFNITVIEFFKLIVIDILGGRSVRIAPDTANKGLISGICGNLEMNDADDFTTDADQLAIQPNINKEFDGCPFYGNPSDIEYCKGLMEPYRAVCRNNINFYYYTLSCAFAYCMGGEERAKHVLFDYVETCAAPETRGTCVLSGHTFYDTFDKARYQFQGPCKEILMAADCYWNTWDVKVSHRDVESYTEVEKVTIRKQSTVVDLIVDGKQVKVGGVDVSIPYSSENTSIYWQDGDILTTAILPEALVVKFNFKQLLVVHIRDPFDGKTCGICGNYNQDSTDDFFDAEGACALTPNPPGCTEEQKPEAERLCNNLFDSSIDEKCNVCYKPDRIARCMYEYCLRGQQGFCDHAWEFKKECYIKHGDTLEVPPECQ
What are the official names of this protein?
Luciferin 2-monooxygenase, Cypridina-type luciferase.
Protein: HTPG_YERPA
Sequence: MNMKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPELFEGDGELRVRLSFDKEKRTLTLSDNGIGMTRDEVIDNLGTIAKSGTKAFLESIGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAPADTGVFWESAGEGDYTIADITKDERGTEITLHLREGEDEYLDDWRLRSVISKYSDHIALPVEIQVKNEEDGTVTWEKINKAQALWTRGKAEISDDEYKAFYKHIAHDFTDPLSWSHNRVEGKQEYTSLLYIPAQAPWDMWNRDHKHGLKLYVQRVFIMDEAEQFMPNYLRFVRGLIDSNDLPLNVSREILQDSRITQNLRSALTKRVLQMLEKLAKDDAEKYQQFWQQFGMALKEGPAEDGSNKETIAKLLRFASTHTDSSAQTVSLEDYVSRMAEGQEKIYYITADSYAAAKSSPHLELFRKKGIEVLLLSDRIDEWMMSYLTEFEGKAFQSVSKADDSLNKLADEENPEQQEAEKALEPFVERVKTLLGERVKDVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQQAPEVKYIFELNPDHGLVKRAAEVTDDTQFAQWVELLLDQALLAERGTLEDPNQFIRRMNQLLTA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_SYNP6
Sequence: MSSGPRVSVAQPRLLFAASGTGGHVFPALAVAEALPEAKIDWLGVPDRLETQLVGDRYPLHTIRVGGFQGSWLLRPLTALRLIGAIFKVRRLLKRQQIEAVFTTGGYIAGPAIAAAWSLGIPVVLHESNALPGKTTRLLSRFCRRVALGFAEAGEYLPGRPLQVVGTPLRSQFYQPSQHGLPIPENVPVLLVMGGSQGAVAINRLVRAAAPAWLAAGLWIVHLTGQQDPDRGQLQHPQYIELSFVDNVAPLLNRADFSISRAGAGSLAELAAAGLPSLLIPYPFAAEDHQTFNARIFAKAGAAILAPQSELTVEQLQQQILDLLRARLGAAIANPLPKMAAAAGKLHVADSAEQVANLLRSLL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHX26_ARATH
Sequence: MNNSVTSNGTHEFVCEAWLGSSSGGLLRGDDPLKYSTPLLLLLISLVSSLSSVFQALLRPLANVDFVTQILAGIFLGPSALGQNIDLVKKLFNTRSYFIIESFEAISFMFISYISTAQVDMGVIKRGGKLAIINGLSLFLFPYVVGAIACTVITSNIRGTVAKNNPEQLHNLLTNQSVVYFQVAYSVLSNLKMLNSEPGRLALSSIMVANCFGWGFFLLLITFDSFLHQNYSKTTYLPTFTKVLLLVGIVVVCRPIFNWIVKRTPEGKKLKASHLCTICVMLCTATFLSETVGFPYVVGSVALGLVTPKTPPFGTGLTDKIGSFCYAVLMPCYVIGIGNKVDFFSFNLRDIISLEFLIFTISAAKFASIVLPSLYFQVPISHAVIVGFIVCIQGIYDVQIFKQLLNYKNISHEAFGIMVISAMVHSTIFTAIVKNLYGWVQRKHITYRRQTVQHYEPNKPLKILTCFYHRETVPPILTVLELSTCPSSASSHSIVSVNLEELEQNNVPLLIQHHPGHNDESSTSSSRRDQISKAFEKFRSGHDLQENVSVECFTAVAPSKTMHEDVCALAFEKETDLIIFGMADGTAAERRLCRNVRNASPSSVAVLMDQGRLPDFKNMGTAMKNGSMRINICSIFLGGADDRETLAFAVRMTNQPYVNLTVLKLVDGENVSHLNDVVEKRLDFRTIEKFRQDTMNKHNVALREVWIKEASDLVNLLREEGNNYDLIMVGIRHEKSFEVLQGLSVWSEIEELGEIGDLLVSRDLKLSASVLAVQQQLSSVVEEV
What is the function of this protein?
May operate as a cation/H(+) antiporter.
What are the official names of this protein?
Cation/H(+) antiporter 26, Protein CATION/H+ EXCHANGER 26, AtCHX26.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1075_LATSS
Sequence: MALEMTQRQGIVVWLYSLRQVKQLRRYGLVYYTSKRMKYVYLYVDADQAPAVIERLKKLHYVKRVTRSQRPMLDMEFGALAELANQETATKAALKE
What are the official names of this protein?
UPF0298 protein LCA_1075.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOS3_HUMAN
Sequence: MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC9 and EXOSC5.
What are the official names of this protein?
Exosome complex component RRP40, Exosome component 3, Ribosomal RNA-processing protein 40, p10.
What is the protein family that this protein belongs to?
Belongs to the RRP40 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: AROE_BUCAT
Sequence: MFKCKNFNYAVFGNPINHSKSPEIHSLFSKQTGISHFYKSCNVPLNSLYAVLQDFFKKDGRGANITAPFKQEAYFFCNKLTKRAEVAQSVNTLKKIDNCNILGDNTDGIGLLSDLIRLNFIKKNYSILIIGAGGAARGVLFPLLSYGCSICIFNRTVLNAEKLVLQFHKYGNINVFNTNSLHVKSFDLIINATSHFIQDKDNFIPFSCVSSKTCFYDMNYQTDNTFFFDWSRKTGSNFFSNGIGMLVFQAAHSFFLWHNVLPEIDYIIDLLNK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: FBID_MYCPA
Sequence: MSGKRADGGHDGAGDVALIIAVKRLAAAKTRLAPVFSARTRESVVLAMLTDTLTAATRVPSLGSITVITPDEAAAAAAAGLGADVLADPTPEGHPDPLNNAIATAERAVSGSFTNIVALQGDLPALQSQELAEAVAAARAHRRSFVADRLATGTAALFAFGTRLDPRFGSDSSARHRSSGAIELTGAWPGLRCDVDTPTDLAAARRLGVGAATARAIAAH
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: CP144_MYCTU
Sequence: MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDPYPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSNLTATMTYTAEGTAKPFEMDPLGGPTHVLATADDPAHAVHRKLVLRHLAAKRIRVMEQFTVQAADRLWVDGMQDGCIEWMGAMANRLPMMVVAELIGLPDPDIAQLVKWGYAATQLLEGLVENDQLVAAGVALMELSGYIFEQFDRAAADPRDNLLGELATACASGELDTLTAQVMMVTLFAAGGESTAALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRNATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGKGAHFCVGAALARLEARIVLRLLLDRTSVIEAADVGGWLPSILVRRIERLELAVQ
What are the official names of this protein?
Cytochrome P450 144.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CLPX_MYCLB
Sequence: MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVQLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAGEKGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFGLIPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELEFTNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRTERRDKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: DCD_SHEFN
Sequence: MRLTDIEIEQCLDNGTIIIDPRPGIEAISGVSVDVRLGSQFRVFKDHTAPYIDLSGPSAEMQIALDRIMSDKIEIADDQAFFLHPGELALAVTYESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFFNSGKLPLALRPGMTIGALNFERLSSAVARPYNTRKSSKYKDQQEAVASRISQDK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PGK_WOLPP
Sequence: MINVPSIESCDFHNKNVLLRVDFNVPIKNGRICDATRILRALPTIQYLANAGAKVIVISHFGRPKAKDSNLSLKNVVETLSRLLSKEVKFIDDCIGERVQRAINAMDGGDIILLENLRFYKEEEQNDSNFAKQLASLADIYINDAFSCSHRAHASISRITEFLPSYAGFCLQDELKYLEQAISFDAKPITAIVGGAKISTKIKMLIKLAEKVDYLILGGAIANNFLLFNKVNIGKSFFQNGVDDLLHDIVETANKNNCKIVVPEDVLVAVNSDYSTGVLRKIESILDGDIILDIGPQTLSTISGIIASSKTLLWNGPIGVFEHSAFANGTVEVMRVVSDLTHEGKLTSVIGGGDSLSAINTAGLADKDFTYISTGGGAFLSWLSGDEMPGLRSTLD
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_ECO27
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSHMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.