PharMolix/UniProtQA huggingface dataset:
Protein: ARGR_MYCLE
Sequence: MTHGASKTTPETTRAGRQARIVAILSSTSVRSQSELATLLADDGIDVTQATLSRDLEELGAVKLRGADGGVGVYVVPEDGSPVRGVSGGTARLSRLLSELLVSADSSANLAVLRTPPGAADYLASAIDRAALPYVVGTIAGDDTVFVAAREPMTGSELATVLESLNR
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_CAUVC
Sequence: MTLTLVKAWTAAKDRLKDAGIDQPSIDARLMLEVAAGVTRTEIVTDPYRELSAEQIATLNDYLERRARREPVSHIIGRKGFWKILLQVNKNVLTPRPETEVIVDEVLKAFPEHMAFSMLDLGVGSGTILLAVLAERPAAKGLGIDASSEALAVARENAANLDLNTRAALLHGDWTTGLGSDSFDLVVSNPPYIPTEVIDTLEPEVRIHEPRLALDGGPDGLAAYRELAPEILRVLKPGGLFAVEIGYDQSQAVEALFRAAGATEVRTVKDLSTHDRVVLGVKNPLESPA
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: RL15_CARHZ
Sequence: MRLHDLRPVPGSRQKPTRKGQGIGSGLGKTAGRGQKGQKARSGGGVRPGFEGGQMPLYRRLPKRGFHNKFAKEIIAINVDRLNKFEDGTVVTPELLLETGIIKKIGDGVKILGGGELKKALTVKAHAFSESAKEKITAAGGQAEVL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RR7_SCIVE
Sequence: MSRQTPARKRRKKYSEKSDAIYHNRLVNMLVNRILKNGKKALAYKIFYRSMKTIYENTNINPLLIIRQAIQTLTPKVMVKARRVTGTTHQIPIDVKPKQGTILAIRWLLESSRKRSGQTMHDKLSHEIMDAARNKGHAIRKKEETHKMAESNRAXAHYR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GEM1_USTMA
Sequence: MRKDVRIVLAGDPDVGKSTLITSLVKEAYVAKVQKVVPPITLPPEVAPEAVVTKIVDTSSSPEHRANLEAELRRANVICIVYSISAPSSFDRIPTYWLPYIRSLGVNVPVILVGNKIDLRSGDVTNAALEDELAPVMAEFKEVETCVECSARIPLNVSEVFYFAQKAVLYPTAPLYDSREHVLKPACVDALKRIFRLCDSDKDGLLSDGELNDFQRKCFDTPLQAQELEGIKDLVVQAPIAGLRYNHENSSVAASGSSANGDIPSHHPHLREGSLTMAGFLYLHTLFIQRGRLETTWTVLRTFGYGVDLSLQDSFVKPAFAVPPECSVELSPNGYQFLTDIFEVHDKDRDGALSEEELDSLFITAPDNRHPWQGTGFPTSTITDEHGAVTLQGWLAQWSMTTLLDHRTTLAYLAYLGYPSFPLSGSSGSASTPAPIPLTPTGPPGSRPSRNRTPCPPSTITALKLTRPRKTDKKKKGAIQRSVFLGFVLGAAGSGKTAILRNMVGKRFANAYEPTQKMMSVVSTVEQAGAERYLVLQEFGSRYEAEVLRNTAKLSAADVIVFVYDSSDTNSFSYISNLRQQYPLLQSMPSLFVATKADLDLAQQRHEVQPDTYCRKLGLKIPGLGAGPLNISIRDGQSADLYGLICTIAVDPKGAVQGGYDRNALSYGTNRWQFWGYIGLVVIGGGGAVWICAKVLKVPIGSTLGFGSSASTTSWWLSGAQARGAGGPNATKVSSWFDWIRWQSSSNVRSEL
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
What are the official names of this protein?
Mitochondrial Rho GTPase 1, GTPase EF-hand protein of mitochondria 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: TNG6_DROME
Sequence: MINTAKYFALLESLRFSKALANTANNSGTAEALEINLRILEKYAKLEIGQQLHELCLEYQLTDDHESSIDPDSDRTICYIIRLQHVLHSIMRNINFHSDAKEDLISVAHLKLCIQASQELSYYSLRCQLHEDFYKSPIFCEAQGKIKANFSLMLLSIQFFINLLHIRQYHIANSMELVQRDLLAAIVSLRVQQDSPLLDKAIAYLWQYESKADFFRNILLFKATTLCPTLAQLLHRQLLGKLHLPQGFASLVEALHQNPNVNSSRNAEIVASIVARKGFSQLAQEKMVLQVLEYCKFYLQNADKMCAGVLSLRRLYDLSDTNQKLIKEILFKHWETLCNPEDIINGLILMDHQELCNRILLWQHLFCSSTVACLPSNLLVPYLPLLLQLYDGLPMELPASSQISAIILRCLDNREMKNELPAILQKLFKWEIEKEPPWKCLNPRIIILPSMNTTQIQVKVAHKDHLADHDMGRILPGLLTSSSHHSLTCKVFLSLLGFIAKQINDKSSASVDFISSEAELKDFLHSKYQLKLDLLIALNQMVAHQPLRAQLSQHTKELLHILKDLLVHRSREQDTTDQILLLVLNLLQEILEGSENIQLSEACKELKEQLHLLGTRSSNPLIQQSVKSLLTIIHGAWRPSEAVKIQPFQRARSLIEEKQSHMQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLFVSLVHVMESDVLDKLSDEYLSETAHLDYRLVVGEAILKVAQELGPLCFRYKAVLLNCFMYGSRSPVHEFRMSAFANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLNGMENLLDYQEMLLPIYRLLKAIEADESCDPQMRQHAANGLKILNKKCTKLIQSALEEKSLQKQIKVLGIKDDDSPQRRNRHILELN
What is the function of this protein?
May be involved in protein secretion and Golgi organization.
What are the official names of this protein?
Transport and Golgi organization protein 6.
What is the protein family that this protein belongs to?
Belongs to the Tango6 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: TRIM5_SYMSY
Sequence: MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKTSMPDEGERSCPVCRISYQHKNIQPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDRKVICWLCERSQEHRGHHTFLTEEVAQEYQVKLQAALQMLRQKQQEAEELEADIREEKASWKTQIQYDKTNILADFEQLRHILDWVESNELQNLEKEEKDVLKRLMRSEIEMVQQTQSVRELISDLEHRLQGSVMELLQGVDGVIKRMKNVTLKKPETFPKNRRRVFRAADLKVMLEVLRELRDVRRYWVDVTVAPNNISYAVISEDMRQVSSPEPQIIFEAQGTISQTFVNFNYCTGILGSQSITSGKHYWEVDVSKKSAWILGVCAGFQPDAMYNIEQNENYQPKYGYWVIGLEEGVKCNAFQDGSIHTPSAPFIVPLSVNICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: PSB3B_ARATH
Sequence: MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-3-B, 20S proteasome beta subunit C-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH60_ACHLI
Sequence: MSKEIRYGKDAKQSLLKGVDLLANTVKITLGPKGRNVVLDKGYGSPLITNDGVSIAKEIELKDPYENMGAKLLYEVASKTNDVAGDGTTTATLLAQSIIHKGFKAVDNGANPVLVREGILRAGKEVSQKLLEKSRPVETSEDIENVASISASSREIGKIIAEAMDKVSKNGVISVDESKGFETELEVVEGMQYDKGYISPYFVSDRETMTVELENPHVLVTDQKISTIQDILPILEQVVKANKPLLIIADDIENEVTSTLILNKLRGTFNVVATKAPGFGDNQKDMLNDIAILTGATFYAKDLQMKLQEIKLEDLGLVQKAVVKKDTTTLIGGHGTKDAIDKRILEIEAQINSSTSDYDKKRLQERLAKLAGGVAIIKVGAATEAELKEKKLRIEDALNATKAAILEGIVAGGGSVLVDIQTELKETLKDSHIDIYKGILAVLDSLSEPLYQIAENAGFDGQDILTEQRKQNKNYGFDAKEGKWVNMLKEGIIDPTKVTRNAILNASSIGALMITSEAAVVEIKDKDQNIPTQPMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PYRFU
Sequence: MAKLKEPIIAINFKTYIEATGKRALEIAKAAEKVYKETGVTIVVAPQLVDLRMIAESVEIPVFAQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRMILADLEAAIRRAEEVGLMTMVCSNNPAVSAAVAALNPDYVAVEPPELIGTGIPVSKAKPEVITNTVELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGVTKAKDPEKAIWDLVSGIIKE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EID3_RAT
Sequence: MSEEKCSLTGGEEKGEELARSLAWQHLVKQAEEDDDDDEEALKKEEEEEEEEEEEDEEEEEEGPDSSSDDLSPEAPCMHPDLLELAVDREKCRSIRRQYRQLIYTVQQNREDIVNTASDSLTEALEEANVLFDGVSRTREAALDAQFLVLASDLGKEKAKQLNSDMSFFNHVAFCELLLVFVGLNWMEEECEELSECDESIALSFWNMLHKEATAWMLQAETFHFIFGSFKAERSARKPRQEHHKRACKMEGNGDMPTKLRKLDVHANQETTEKEVERILGLLQTYFQKYPDTPVSYFEFVIDPNSFSRTVENIFYVSFIIRDGFARIRLDQDRLPILEPTNVNQVDEENDSCSYCRKQGVISLSLQDWKNIVSTFEISEAMIKNSY
What is the function of this protein?
Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation.  May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors (By similarity).
What are the official names of this protein?
EP300-interacting inhibitor of differentiation 3, EID-3, E1A-like inhibitor of differentiation 3, EID-1-like inhibitor of differentiation 3, Non-structural maintenance of chromosomes element 4 homolog B, NS4EB, Non-SMC element 4 homolog B.
What is the protein family that this protein belongs to?
Belongs to the NSE4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome, telomere. Note=May shuttle between nucleus and cytoplasm.
Protein: H8_NEIMB
Sequence: MKAYLALISAAVIGLAACSQEPAAPAAEATPAAEAPASEAPAAEAAPADAAEAPAAGNCAATVESNDNMQFNTKDIQVSKACKEFTITLKHTGTQPKASMGHNLVIAKAEDMDGVFKDGVGAADTDYVKPDDARVVAHTKLIGGGEEASLTLDPAKLADGEYKFACTFPGHGALMNGKVTLVD
What are the official names of this protein?
Outer membrane protein H.8.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL23_STRPJ
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: COBT_ECOSE
Sequence: MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAVKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL5_STRGC
Sequence: MANRLKEKYLKEVVPALTEKFNYSSVMAVPKVDKIVLNMGVGDAVSNAKNLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTTANTDEESRELLTGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y126_CLOAB
Sequence: MAKGGFPGMGGGNMNNLIKQAQKFQKQMEDMQKEIENKEFTATVGGGAVSATVSGKKEITEIKIKPEVVDPDDVEMLQDLILSACNEALKKAEEETSGEMKKLTGGLNIPGL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CA_C0126.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SRP09_HUMAN
Sequence: MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVAKEARNVTMETE
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (PubMed:11089964).  The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity).
What are the official names of this protein?
Signal recognition particle 9 kDa protein, SRP9.
What is the protein family that this protein belongs to?
Belongs to the SRP9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPFF_BOVIN
Sequence: MDARQAAALLLVLLLVTDWSHAEGPGGRDGGDQIFMEEDSGAHPAQDAQTPRSLLRSLLQAMQRPGRSPAFLFQPQRFGRNTRGSWSNKRLSPRAGEGLSSPFWSLAAPQRFGKK
What is the function of this protein?
Morphine modulating peptides.  Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas.  The neuropeptide FF potentiates and sensitizes ASIC3 cation channel.
What are the official names of this protein?
Pro-FMRFamide-related neuropeptide FF, FMRFamide-related peptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSM4_METJA
Sequence: MKMVVLKPKINSKFHFGEGSLERNSKIFHSNSLFSAIVNNYIKLYGREDLEKNIEKIKNIRLSSLLYKIKNIYLIPKPEHPEFYKLKGNPGIKPKDIKKIQFFSIKAYKELLDNELDWKNKIKHIVDYQTINKSIVISEKEIEEIKRIFGIKAEKLKHAKISLISKHLEQKVAIDRLKDITLEKDDKGQLYNIEFIKLNENVEFYFLIDYNNEDKEFIKKLEASIKLIEDEGLGGKRSIGAGFFEKVEIVDLPEDFNEILDENSKYNNLEYKMLLGVGIPNKDDIKNIEYYKLIEIGGYIYSLECLTKPKRNILALTEGSIVKNDFIGDVKDISPQNDDDEQNKNNENNNKLNHKVYTHGKPILLPFNPKRDNYGS
What is the function of this protein?
The subunit probably binds to the 5' handle of the crRNA, helping in discrimination between self- and non-self (Probable).  The Csm3-Csm4 complex binds both crRNA and a non-specific RNA; Csm4 alone also binds RNA (PubMed:25451598).
What are the official names of this protein?
CRISPR system Cms protein Csm4, CRISPR type III-A associated RAMP protein Csm4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm4 family.
Protein: ARLY_AQUAE
Sequence: MEKPWSGRFKEETDKFVEDFTESVSFDKELAFEDIEQDIAHVKTLQKAGILTEEEARELIQELLKIKEEIKEGKFQWKKELEDVHMNIEAELINRLGDVGRKLHTARSRNDQVATDEKLYLKKEIKEVLQLLKELRKTLVELAETTVDFVMPSYTHLQRAQPIRVAHYFLAYREILLKDSERLMDTYRRVDELPLGSGAVAGVDFPLDRFYTAELLGFNRVTRNSMYATAERDFIIEFLSNCALIAQHLSRLAEDLIIWNTEEFNFVELPDKLCTGSSIMPQKKNPDVLELIRGKTGRIYGNLIALLTTMKALPMAYNRDMQEDKEPLFDTLKNLKNMIKGMTLVLSDLRVKEQNMRKASGNFLLITDIANYLVEKGVPFRTAHHIAGSIVAYLLEKGKKLEEMTLEEFKQFSEKFEEDVFDILSPERAADRKRVYGGTAKEEILRIIEVAKAEEGL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIS_SULIL
Sequence: MGTFTLHQGQSNLIKSFFRNYYLNAELGLPNDMELREFALQPFGSDTYIRHLSFSSSEELRDYLVNRNLPLHLFYSSARYQLPSARDMEEKAWMGSDLLFDIDADHICKLRSIRFCPVCGNAITSEKCERDNVETLEYVEMTSECIKRGLEEARNLVEILEDDFGLKPKVYFSGNRGFHVQVDCYGDCALLDSDERKEIAEYVMGVGVPSYPGGSESAPGWVGRKNRGINGVTIDGQVTIDVKRLIRIPNSLHGKSGLIVKEVTNLDDFEFNEALSPFTGYTIFLPYISIETEVLSRNIKLNRGVPIKIESSIGIYLHLKNLGEVKAYVR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: COBT_PSET1
Sequence: MFKIAPLNNQFDHLIHNKINNKTKPLGALGQLELIALQLVKILSQTIKSDVEFTAFKAEICNPTLVVFAGDHGIAAQGVSIAPSEVTAQMVANFVAGGAAINIFCQQLGWQLEVVDCGILEKSPASKVHDCRLGNITAPLNLHMAMSTAQVKQGFSNAKSLVLQLKQQGCNTLAMGEMGIGNTTSAAAIMAAILNLPVTQCVGRGTGVSDELIARKINVVEQALQLHKAHLADPIALLAAVGGFEIVHITGAMLAAAEQGMAVIVDGFICSAAAMVAIKINPIVKEYLIFAHCSNEQGHQQMLSKLEVKPLLQLDLRLGEGTGAALSLPLLQAALGFYNHMASFADAGVEQVV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: DJB11_BOVIN
Sequence: MAPQNLGTFCLLLLYLIGTVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPRAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHSIFERRGDDLYTNVTISLVESLVGFDMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLSEEAREGIKQLLKQGSVQKVYNGLQGY
What is the function of this protein?
As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins.  Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed.  May help recruiting HSPA5 and other chaperones to the substrate.  Stimulates HSPA5 ATPase activity.  It is necessary for maturation and correct trafficking of PKD1.
What are the official names of this protein?
DnaJ homolog subfamily B member 11, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, Endoplasmic reticulum DNA J domain-containing protein 3, ER-resident protein ERdj3, ERdj3, ERj3p.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PAEA_ECOLI
Sequence: MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINAQRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSFILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANIIFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA
What is the function of this protein?
Involved in cadaverine and putrescine tolerance in stationary phase.  May facilitate the efflux of both cadaverine and putrescine from the cytoplasm, reducing potentially toxic levels under certain stress conditions.
What are the official names of this protein?
Polyamine export protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family. PaeA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PMGT1_RAT
Sequence: MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLESPRHRGSSPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVLGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRKSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEIHRLLSEAEVLDHSKDPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAAEQT
What is the function of this protein?
Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins.  Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties.  Is specific for alpha linked terminal mannose.
What are the official names of this protein?
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1, POMGnT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: NU3C_ANGEV
Sequence: MFLLPKYDSFWLFLLIASLIPVSAFSISKILAPVSQGPEKLTSYESGIEPMGDAWIQFQIRYYMFALVFVIFDVETVFLYPWAMSFKELGISAFIEALIFVLILIIGLIYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.