PharMolix/UniProtQA huggingface dataset:
Protein: DNCH_SYNP2
Sequence: MAYAYRRTIHLADTDAAGVVYFAQLLHICHEAYEICLIGNGMDWSGLLREGTVALPIVHSAIDFLRPITWGDRLDIQLYPELENSRQFKISYRIFKENQDSPPESPLATALTRHVAINPRTRQRCSLPPVVETWLRNAPKIEDSKI
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: SIK3_MOUSE
Sequence: MAAAAASGAGGVAVAGAGGAGPAGRLLPPPAAGPPAAPAAVPPAAVPARPTAPASRGSMAARIGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKSQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICRHKWMKLGDADPNFDRLIAECQQLKEERQSDPLNDDVLLAMEDMGLDKERTLQSLRSDAYDHYSAIYSLLCDRHKKHKTLRPGALPSMPQAMTFQAPVNLQAEQTGTAMNLSVPQVQLINPENQIIEPDGAVNLDSDEGEEPSPEALVRYLSMRRHTVGVADPRTEVMEDLQKLLPGFPGVNPQGPFLQVAPNMNFTHNLLPMQSLQPTGQLEYKEQSLLQPPTLQLLNGMGPLGRRASDGGANIQLHAQQLLKRPRGPSPLVTMTPAVPAVTPVDEESSDGEPDQEAVQRYLANRSKRHTLAMTSPTAEIPPDLQRQLGQQSFRSRVWPPHLVPDQHRSTYKDSNTLHLPTERFSPVRRFSDGAASIQAFKAHLEKMGNSSSIKQLQQECEQLQKMYGGQVDERTLEKTQQQHMLYQQEQHHQILQQQIQDSICPPQPSPPLQVACENQPALLTHQLQRLRIQPSSPPPNHPSNHLFRQPSNSPPPVSSAMITSHGATSPSQFQGLPSHGAIFQQQPENCSPPPSVALTCLGLQQASQSQPVTIQLQEPVDMLSNMAGTAAGSAGRSIPISPSASQIQIQHRASLMAPFSYGHRPLSKQLSADSAEAHSLNMNRFSPANYDQAHLHPHLFSDQSRGSPSSYSPSTGVGFPPTQALKVPPLDQFPTFPPSAQQQPPHYTTSALQQALLSPTPPDYPRHQQVPHILQGLLSPRHSLTGHSDIRLPPAEFAQLIKRQQQHRQQQQQQQQQQEYHELFRHMNQGDAVSLAPSLGGQNMTEQQALSYQNADSYHRHHTSPQHILQIRAQDCISQGPSPTPTHGYAHQPPLMHSESMEEDCLCEGLKEGFPDKSSSTLTKGCHNSPLLLCTSGPGDPEPLLGTVSQARELGIHPYGHQPTATTFSRNKVPSRESVLGNCLERSSPGQAMELPDHNGLGYPVRPLVSEHLRSRTLQRHHTIQNSDDAYVQLDTLPGMSLVAGKALSSARMSDAVLSQSSLMGSQQFQDEEDEECGVSLGHEHPGLGDGSQHLNSSRYPATCVTDIMLSHKHPEVSFSMEQAGV
What is the function of this protein?
Positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor (By similarity).  Required for chondrocyte hypertrophy during skeletogenesis (PubMed:22318228).  Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3 (By similarity).  Prevents HDAC4 translocation to the nucleus (PubMed:22318228).
What are the official names of this protein?
Serine/threonine-protein kinase SIK3, Salt-inducible kinase 3, SIK-3, Serine/threonine-protein kinase QSK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Locates to punctate structures within the cytoplasm on binding to YWHAZ.
Protein: MTMR9_BOVIN
Sequence: MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSTISEWRLSYVNKEFSVCPSYPPAVIVPKAIDDDALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNIAQQARAKGGGFEQEAHYPQWRRIHKSIDRYHILQESLIKLVESCNDQTQNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSKQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNLLRRQLAELETEDGVQESP
What is the function of this protein?
Acts as an adapter for myotubularin-related phosphatases.  Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate, and MTMR6 binding affinity for phosphorylated phosphatidylinositols (By similarity).  Positively regulates lipid phosphatase MTMR7 catalytic activity (By similarity).  Increases MTMR8 catalytic activity towards phosphatidylinositol 3-phosphate.  The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels.  Stabilizes MTMR8 protein levels.  Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles.  Negatively regulates autophagy, in part via its association with MTMR8.  Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6.  Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine (By similarity).
What are the official names of this protein?
Myotubularin-related protein 9, Inactive phosphatidylinositol 3-phosphatase 9.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Localizes to ruffles during EGF- induced macropinocytosis (By similarity). Colocalizes with MTMR6 to the perinuclear region. Partially localizes to the endoplasmic reticulum (By similarity).
Protein: DNLJ_SHEPC
Sequence: MQDIQLDKLLSADMSPENAQQVMQALSQSLNEHNIRYYVDDAPTITDSEYDRLMQCLIKLEAQFPQFIVADSPTQRVGGLALAKFDQITHLKPMLSLDNAFGEADFSAFHKRVTDKVGEVSFCCEPKLDGLAVSILYRHGVLERAATRGDGTVGEDITENVKTIKSIPLKLRGNDFPEVVEVRGEAFMPKAAFEALNERARAKDEKLFVNPRNAAAGSLRQLDSKITASRSLAFYAYALGVVEPDSYSLGKTHYEQLQQLKSWGLPVSNEIKVCDELDQVFDYYKDILTRRSDLPFEIDGVVMKVNDIAQQQRLGFVAKSPRWAIAYKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIERLGIKIGDTVIIRRAGDVIPQIVAIVPERRPETATNIVFPHNCPVCGSLVERLEGEAVARCSGGLFCEAQRKEAIKHFASRKALDIDGMGDKVVEQLIDKELVQSPADLFKLTASMMTMLDRMGMKSATNLAAAIEAAKTTTLARFLYALGIREVGEATAANLAAHFASLDALRVATVEQLTAVEDVGVVVAQHVAHFFAQPHNLEVIDALIAAGVHWPAIEAPSADAQPLKGQTWVLTGTLNQLNRNDAKAQLQTLGAKVAGSVSKNTDCLVAGEAAGSKLAKAQELGVKVIDEEALLALFAANR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AT1A4_HUMAN
Sequence: MGLWGKKGTVAPHDQSPRRRPKKGLIKKKMVKREKQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.  Plays a role in sperm motility.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-4, Na(+)/K(+) ATPase alpha-4 subunit, Sodium pump subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=In mature sperm, located in the principle piece of the sperm flagellum.
Protein: ERIC5_HUMAN
Sequence: MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRNIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT
What are the official names of this protein?
Glutamate-rich protein 5.
Protein: YIIF_ECOLI
Sequence: MGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVDQYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW
What are the official names of this protein?
Uncharacterized protein YiiF.
What is the protein family that this protein belongs to?
To E.coli YiiE.
Protein: PDXH_AERHH
Sequence: MDVADLRREYTRGGLHRADLPAEPLALFEKWLAQACEAKLTDPTAMVVGTVDADGQPWQRTVLLKHYDAEGMVFYTNMGSRKAHQLEGNPRISLLFPWHTLDRQVHVTGRVEKMSTFEVMKYFHSRPKDSQIAAWVSQQSTRISARGVLEAKFLELKQKFANGEVPLPSFWGGFRVRIDTVEFWQGGEHRLHDRFYYTREGEGWHIERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: OBG_AZOVD
Sequence: MKFVDEVSIFVKAGDGGNGMMSFRREKFIEKGGPNGGDGGDGGSVYLEADENLNTLVDYRYTRRFEAQRGEKGGSNDCTGAKGDDLILPVPVGTTVIDSGTQEIIGDLVRPGQRLLVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEARDLKLELKVLADVGLLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPNLGVVSVGRYKSFVVADIPGLIEGAAEGAGLGIRFLKHLARTRLLLHLVDMAPLDGGDPAGAAETILRELEKFSPALTERERWLVLNKADQLLDEEREERLRAVLERLDWQGPVYVISALEREGTEALCQDIMHYLDERARRIAEEPEYAEALAELDRHIEDEARTRLQALDDQRALRRAGLKSADALEDEDDFDDEDDGDGPEIFYVR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MICLC
Sequence: MALIDAIHAREILDSRGNPTVEVEVLLTDGSLGRAAVPSGASTGEFEAVERRDGDKKRYGGKGVLDAVAAVEGIAEELEGEFAADQRAVDRAMRDLDGTPNKGKLGANAILGVSMAVAVAAAQASDLMLYKYLGGPNSHVLPVPMMNILNGGAHADSNVDIQEFMIAPIGAPSFREALRWGTEVYHALKTVLQEKGLSTGLGDEGGFAPSLESNRAALDLIAEAVTKAGYRLGEDIALALDVASSEFFDKGSYTFEGQQRSAEEMAAYYTELVDNYPIVSIEDPLDEDDWEGWQHLTAQLGDRVQLVGDDLFVTNVERLQRGIDEKAGNALLVKVNQIGSLTETFDAISLAQRHMFHCMISHRSGETEDTFIADLAVATNAGQIKTGAPARSDRVAKYNQLLRIEEDLADAAVYAGRSAFPRFRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PKH2_CANAL
Sequence: MHKFRYSLHQHYSKRNSSDKSKDSPISQNSNEENDSTKLSSSSLQDLHDDLDDIYNNYTLAQGTNNNSVDTLDSENNQAINKFIDKPPAIHGMEPQLPVMHVSSRLSSLGNTTNETGESIAKSAPGTPLSSHSFDFRPHHPRAVTNSSLNVLLDTPNVSSEFNHLVDQTPPNESVERFDDSNNTVDNTEEEENNDDTDEIPKSETLKQNEENWEKKGAAVKTIKTMDGEMKTIRRNVTDFKFGKELGEGSYSTVILATDKITGKQYAVKVLDKRHIIKEKKVKYVNIEKHALNRLSNRLGVISLYFTFQDKDSLYFVLDYASNGELLTLIKRYNTLNEECTRHFGAQILDAIKYMHDNGVIHRDLKPENILLDDKMRIQITDFGTARLLEKKNDESEEYPVDVRAKSFVGTAEYVSPELLENKYCGKPGDVWAFGCIIYQMIAGKPPFKATNEYLTFQKITKLQFAFSAGFPTIIRDLIKKILVLQPSRRATIPEIQKHYFFQSVDFKDFDSIWLSDPPEIGPYKMTAKSMMKVPELNKAPITTVIKKNVKKSTNSNSNTNNVATAVGGSSSNGHKGSSPTPEKEPSPATINNKSTEKVSAASVAAYVLNKPATNQNSSTSEDSSKRSSNSNETRKLSYSQQDYIPGTNILRPQISTRPSVGSYVKTTPSKDRKTLTKVPSNIHQQQEKVKPKVMEVKPATTLEAAWEPYLTHPDERILRIGPVIAHKEPTEPFEKKNKASLHISPLDINKEQRSRSNTSLLTQIVNEVNNNTSELKKVENADESLAIIEPQYNMKRSPTSDSKKSMDIERSASTSGSRISKKAIFKKLGFSHLEKNDSEESNGPSLTEKPQTCTLVVTTHGRALLFIRNDIESNYLLIAEIKLKYPFIHFQELVISQTKFSKLVPSVGVFVISSIDNSLIFEVEKFEVNQWTEALAKSKYNEIGKR
What is the function of this protein?
Serine/threonine-protein kinase which is part sphingolipid-mediated signaling pathway that is required for the internalization step of endocytosis by regulating eisosome assembly and organization, and modulating the organization of the plasma membrane.  Phosphorylates and activates PKC1.  Activates YPK1 and YPK2, 2 components of signaling cascade required for maintenance of cell wall integrity.  Required for stress-induced P-body assembly and regulates global mRNA decay at the deadenylation step.
What are the official names of this protein?
Serine/threonine-protein kinase PKH2, PKB-activating kinase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cell cortex. Note=Localizes at eisosomes, large, immobile complexes that mark sites of endocytosis near the plasma membrane.
Protein: RL14_BORPD
Sequence: MIQMQTTLDVADNTGARAVMCIKVLGGSKRRYAGIGDIIKVSVKDAAPRGRVKKGEIYNAVVVRTAKGVRRKDGSLIRFGGNAAVLLNAKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DAPE_BURO0
Sequence: MSATLALTEQLIARASVTPDDQHCQQIMTERLAALGFECETIASHGVTNLWAVKRGTDGRDGKLLAFAGHTDVVPTGPLEQWTSPPFIPAHRDGKLYGRGAADMKTSLAAFVVASEEFVAVHPDHRGTIAFLITSDEEGPATDGTVKVVELLQARGERLDYCIVGEPTSTAELGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDAGNEYFPPTTWQVSNLHAGTGATNVTPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLEYTLKWSVSGLPFLTPRGELSGALEHAIRTETGITTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIEVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: G6PI_HAES1
Sequence: MQNINPTQTNAWKALEQHQKDLDQVTIQQLFEQEPTRFNDYSLKFAEQILVDYSKNNINQQTLSLLRQLAKECALNEATEAMFNGEKINRTENRAVLHTALRSCANTPVYVDGKDVMPEVNAVLAKMKSFCQRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLTMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAISARKWFLAAAQDESQIANHFAALSTNAKEVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFDNFEQLLAGAHEMDNHFRTAPMEQNIPATLALIGIWNCNFLGAETEAMLPYDQYLHRFAAYFQQGNMESNGKYVARNGEVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTKIIPCDFIAPAQTHNPLSDHHSKLLSNFFAQTEALAFGKTQQEVEAEFVKAGKSLDEVKEIVPFKVFTGNKPTNSILVQKITPFTLGALIAMYEHKIFVQGVIFNIYSFDQWGVELGKQLANRILPELTGDESISSHDSSTNGLINQFKAWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEB_HEMVI
Sequence: MLDAFSKVITSADGKAAYVGGADLQALKKFVSDGNKRMDAVNAIVSNASCIVSDAVSGMVCENPALIAPNGGVYSNRKMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLNGLKETYASLGVPAAGNARAVAIMKATVNGFINNTAQQKKLSTPAGDCSALASEAGGYFDKVSSALA
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycoerythrin beta subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: GPCP1_RAT
Sequence: MTPSQVTFEIRGTLLPGEVFAMCGNCDALGNWSPQNAVPLTESETGESVWKAVIVLSRGMSVKYRYFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLENEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHFSEKPPVSITKKKFKKSRFRVKLTLEGLEEDDDDDDKASPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDVLPGHVGTACLLSSTIAESERSAGILTLPIMSRSSRKTIGKVRVDFIIIKPLPGYSCSMQSSFSKYWKPRIPLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAFVEFDVHLSKDLVPVVYHDLTCCLTMKRKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTKDQKQCMAEEENSFSENQPFPSLKMVLESLPENVGFNIEIKWICQHRDGVWDGNLSTYFDMNAFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENILGINAHTEDLLRNPSYVQEAKDKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKRELPELKNCLCPTVSHFIPPSFCMESKIHVDANGIDNVENA
What is the function of this protein?
May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity.
What are the official names of this protein?
Glycerophosphocholine phosphodiesterase GPCPD1, Glycerophosphodiester phosphodiesterase 5.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: YGGU_SALDC
Sequence: MSAVTRCEDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLTKFLGKQFRVAKSQIVIEKGELGRHKQVKIIHPQQIPPEIAALTE
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RL21_BRUA1
Sequence: MFAVIKTGGKQYRVAANDLIKVEKVAGEAGDIVEFAEVLMVGSTIGAPTVAGSLVTAEVVEQGRGRKVIAFKKRRRQNSKRTRGHRQELTTIRISEILTDGAKPSKKAAEKKAPKADAAEGEAAKPKKAAPKKAATKAESAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DAPD_HAEIE
Sequence: MSNLQAIIEAAFEKRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIAGEWVTHQWLKKAVLLSFRINDNQIIDGAETKYYDKVALKFADYTEERFTEEGFRVVPSATVRKGAYISKNCVLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDNCFIGARSEVVEGVIVEDGCVISMGVFIGQSTKIYDRETGEIHYGRVPAGSVVVSGSLPSKCGKYSLYCAVIVKKVDAKTLGKVGINELLRSIEE
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAH_ORYSJ
Sequence: MASLVAVQPVAVKGLAGSSISGRKLAVRPSPRALCRTTRRPRAAVVAKYGEKSVYFDLEDIGNTTGQWDLYGSDAPSPYNPLQSKFFETFAGPFTKRGLLLKFLLLGGGSLVAYVSASASPDLLPIKKGPQLPPTPGPRGKI
What is the function of this protein?
Possible role could be the docking of the LHC I antenna complex to the core complex.
What are the official names of this protein?
Photosystem I reaction center subunit VI, chloroplastic, PSI-H, Light-harvesting complex I 11 kDa protein, Protein GOS5.
What is the protein family that this protein belongs to?
Belongs to the psaH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SHQ1_DANRE
Sequence: MITPAFELSQDADFLIVVIRVPYTRTSDFDIYIQEEEFKFYAKPYFLRLTLPGRIVEDGREKASFDIDKGLFTLHVPKETAGQHFEGLEMLTSLLAPKGSRSAKPLVEDSEACGEGCEEEDEEFDWQIEQEVYTEAPADTLKEYHKYGFGNLRSGVFSRLQEELNEVIDMKDPDNTNAELRRRNRLDTETAVFCADHYLVNLYEDKEEIRNLLKFKPWWRKLNPDPSAGYDISMTFTEEEREQMRRFTNRSYLLDKKARFHVWLGLVDIILAYVYDVRTTEGEHNVESAWTIRKLSGTLSWLETYHSVQDVLVSFGRRTYCYPLYRHFSLVTLAVKDAACIFQAGKACILKCLLAIHKIFRENDPAYILNDLYITDYCIWIQRVKSKHVLALAEPLNNAKLQKNHLELELEIIEQAAELAVKEEEEKDTESDTDDSSSSSGDSDDEDDSDEECPEKAAEKKQTAFKAHAEAVTEAFCVELQRGDGRLIEELGKRLEEELTIEEDVPQERRSASEGEGERRREHYHPHAAESERDTTKAATGKELLDVCLQRKPLRILNTEELDSDDDDDDDDDGDLRITVVDERG
What is the function of this protein?
Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs).
What are the official names of this protein?
Protein SHQ1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHQ1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus, nucleoplasm.
Protein: ARV1_DICDI
Sequence: MICIECGRPVNDVYKEFGKAGSGNIRLTRCASCNQTADKYVEYDFIIVFLDLFLHKAQAYRHLLFNRQPYRDFGIPIQYIKVLVVYIFFESYIKWLRFKEYEQHPSGPAFYYIDWQDDVPYDRYWFIFVTAIAEFAVYILSIILSVRFIYESRYPIIKYNYLIMAIILSSFGKGFLVLMMIWDYPFSFGSILNIFVLSSNVVAIKVFLDTTTFKAIFFVVFGFLGKLLFQSIIYLFDASMLLHLSF
What is the function of this protein?
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.  Regulates also the sphingolipid metabolism (By similarity).
What are the official names of this protein?
Protein arv1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ARV1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y420_RICPR
Sequence: MKKIIGLFFIIILIVINISILAYDYPKAEQEQKWDEVDSIAGEGGLIFRPGRVKNESTKAVGCTVNKYLWQAALEIISFIPLASVDSNGGVIITEWYSPRSNTNFRFKINIFIKDDVISPDAIEVKIFEEILKNKQWVLNENTSNLAIMLEDKILRKARDIYINSVR
What are the official names of this protein?
Uncharacterized protein RP420.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: APT_YARLI
Sequence: MSLQTLQTELKAKLRQYQDFPSKGIVFEDILPIFQDPKSFQQLIDAFKLHIKDTFGDKKIDVIVGLDARGFLFGPTLALAIGAAFVPVRKQGKLPGKTVHAEFQKEYGKDVFEIQEDAIKPGQTVIVVDDIIATGGSAACAGDLVTKLKGEVLEFIFILELLFLKGRDKLCAPAYTLLSGQE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCSPB_STAEQ
Sequence: MISKSSPLIFERSKKDRYAYSLPQNDIENISIASLLDDKYIRKHKAEFPEVSELDLVRHYTELSNKNFGVDTGFYPLGSCTMKYNPKINEKVARISGFSESHPLQEEEHVQGSLEIIYSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAYHEKNGQSHRDEVIVPDSAHGTNPASASFAGFKSVTVKSNQRGEVDIEDLKRVVNDNTAAIMLTNPNTLGIFEQDIIEIGKIVHEAGGLLYYDGANLNAILDKVRPGDMGFDAVHLNLHKTFTGPHGGGGPGSGPVGVVEKLASYLPKPMVIKDNDRYKYDNDIPNSIGRVKPFYGNFGIYLRAYTYIRSMGANGLKEVSEAAVLNANYIKSRLKNHFEIPFNQYCKHEFVLSGTLQKQYGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFIDAMIQIADETKNDPDKVLEAPHTTIIDRLDETTAARKPILKFEELKDEKYKEHTNIDSEDN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.