PharMolix/UniProtQA huggingface dataset:
Protein: LMBD1_DANRE
Sequence: MATPVALLSESVLGWSIFTVVLLVILAFCWVYIRKYQSRQESEVISTITAICALAIALITSALLPVDIFLVSFMKHPNGTYKEWAANNETRVQIEDTVLYGYYTLYSIILFCVFLWIPFVYFYYEEKDEDNNNKCLQVKNALKYTIGFVIVCSALLLIGTFVPLASPPNQNSTQWQKVQYLFEELGSSHGLAALSFSISSLTLIGMLAVITYTAYGMSVLPLNLIKGTRSVLYERLENTEDTEEVERQIDKLKAKCADGRPLSMRDRRNLQDLEDKLQLLHRRGRHLEIAERNCCNKVGSALRPMKILLGVFFILVALLFFVTLFISNLDKALHSAGISTGFIIFGTNLTNPLNELLLALQPVFPLDYVLITVITMYFVFTSMAGIRNMGIWFFWIRLYKIRPQRTRPQALLFLCMILLLIVLHTSYMIYSLAPQYVMYGSQKYLLQTPLPTAVPSQSNRSATITKICDADAPEDQCTVTRSYLFLHKFWFFSTIYYFGNWAFLGVFLIGLVVSCCKGKKSVIEGEVDADDSDFSDDEYVH
What is the function of this protein?
Lysosomal membrane chaperone required to export cobalamin (vitamin B12) from the lysosome to the cytosol, allowing its conversion to cofactors.  Targets ABCD4 transporter from the endoplasmic reticulum to the lysosome.  Then forms a complex with lysosomal ABCD4 and cytoplasmic MMACHC to transport cobalamin across the lysosomal membrane (By similarity).  May play a role in mediating and regulating the internalization of the insulin receptor (By similarity).
What are the official names of this protein?
Lysosomal cobalamin transport escort protein LMBD1, LMBD1, LMBR1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: LFTR_TERTT
Sequence: MSQLQWLDADNLRFPPTHSALRDPDGLLAVGGDLSPARLIESYSHGIFPWYSDGQPLLWWTPDPRMVLRPAHVHRGRTLRKLLRQHPFTVTVDSAFDAVAQACGTIEREGQDGTWITQEMLAAYSELNRLGVAHSLEVWLQNELVGGLYGIALGTVFFGESMFSRVSGASKVGFSILCQQLENWGFELVDCQIHSGYLASFGAQEIPRATFEKLLAQHVWNIPRVPSAACYQSPIPTTSRPCPPLINWQMAWTAGEDLA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BURP0
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNNNFAAMLQEDIGVREYLKKKLKNASVGRVVIERPAKNARITIFSSRPGVVIGKKGEDIELLKTELQRRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSAGRLNGIEIARTEWYREGRVPLHTLRADIDYATSEAKTTYGIIGVKVWVYKGDTLGRNDAPVVEEVTEDKRPRRNARPGDRRPRRDGEGGAPGARRGGPRRGAGKPEDGKTGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PURA_SALNS
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A9_ARATH
Sequence: MVSLKSLAAILVAMFLATGPTVLAQQCRDELSNVQVCAPLLLPGAVNPAANSNCCAALQATNKDCLCNALRAATTLTSLCNLPSFDCGISA
What are the official names of this protein?
Tapetum-specific protein A9.
What is the protein family that this protein belongs to?
Belongs to the A9/FIL1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPL1_CAEEL
Sequence: MRSWSTVMLAVLATAATVFGHDADPEMKMTTPQIIMRWGYPAMIYDVTTEDGYILELHRIPYGKTNVTWPNGKKPVVFMQHGLECSSSNWVVNLPTESAAFLFADAGYDVWLGNFRGNTYSMKHKNLKPSHSAFWDWSWDEMQQYDLPAMIEKALEVTGQDSLYYIGHSQGTLTMFSRLSEDKVGWGNKIKKFFALAPVGSVKHIKGALKFFADYFSLEFDGWFDVFGSGEFLPNNWIMKLVSESVCAGLKVEAGVCDDVMFLIAGPESNQLNATRVPIYVAHTPAGTSTQNIVHWIQMVRHGGTPKYDYGEKGNKKHYGQANVPAYDFTTVNRPVYLYWGDSDWLADPTDVTDFLLTHLNPSTVVQNNKLIDYNHLDFIWGLRAPKDIYEPIIDIVRNDVLNGS
What is the function of this protein?
Lipase that, together with lipl-3, plays a role in the response to nutrient deprivation by controlling lipid metabolism (PubMed:23604316).  Specifically, involved in the breakdown of lipids during lipophagy, a process during which lipids contained in lipid droplets that have been delivered to lysosomes by autophagy are degraded (PubMed:23604316).
What are the official names of this protein?
Lipase lipl-1, Lipase-like 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Lysosome lumen. Note=Secreted into the intestinal lumen.
Protein: ATS16_HUMAN
Sequence: MKPRARGWRGLAALWMLLAQVAEQAPACAMGPAAAAPGSPSVPRPPPPAERPGWMEKGEYDLVSAYEVDHRGDYVSHEIMHHQRRRRAVPVSEVESLHLRLKGSRHDFHMDLRTSSSLVAPGFIVQTLGKTGTKSVQTLPPEDFCFYQGSLRSHRNSSVALSTCQGLSGMIRTEEADYFLRPLPSHLSWKLGRAAQGSSPSHVLYKRSTEPHAPGASEVLVTSRTWELAHQPLHSSDLRLGLPQKQHFCGRRKKYMPQPPKEDLFILPDEYKSCLRHKRSLLRSHRNEELNVETLVVVDKKMMQNHGHENITTYVLTILNMVSALFKDGTIGGNINIAIVGLILLEDEQPGLVISHHADHTLSSFCQWQSGLMGKDGTRHDHAILLTGLDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGEGNMCKKSEGNIMSPTLAGRNGVFSWSPCSRQYLHKFLSTAQAICLADQPKPVKEYKYPEKLPGELYDANTQCKWQFGEKAKLCMLDFKKDICKALWCHRIGRKCETKFMPAAEGTICGHDMWCRGGQCVKYGDEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHYKWKPYTQVEDQDLCKLYCIAEGFDFFFSLSNKVKDGTPCSEDSRNVCIDGICERVGCDNVLGSDAVEDVCGVCNGNNSACTIHRGLYTKHHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNALRRYYLNGHWTVDWPGRYKFSGTTFDYRRSYNEPENLIATGPTNETLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQPSYTWAIVRSECSVSCGGGQMTVREGCYRDLKFQVNMSFCNPKTRPVTGLVPCKVSACPPSWSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAPSSRQACNSQSCPPAWSAGPWAECSHTCGKGWRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCHKPKKLQWLVSAWSQCSVTCERGTQKRFLKCAEKYVSGKYRELASKKCSHLPKPSLELERACAPLPCPRHPPFAAAGPSRGSWFASPWSQCTASCGGGVQTRSVQCLAGGRPASGCLLHQKPSASLACNTHFCPIAEKKDAFCKDYFHWCYLVPQHGMCSHKFYGKQCCKTCSKSNL
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 16, ADAM-TS 16, ADAM-TS16, ADAMTS-16.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MUKF_ECOK1
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMVLRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MURB_CLONN
Sequence: MVQSIDINKKLESILDKEEIKNNILMKNYTSFKVGGPADIFVTPNSYEKVKGVINICKENNIPYFILGNGSNVLVRDGGIRGVVVSFNKLNKVYAEGNKVIAESGTLLSMVANTALKSDLTGLEFAHGIPGSVGGAVTMNAGAYNGEISQVIESATVIDNNGKIIKLSKEELDLSYRNSIILKNGYVVLNATFALQKGDHDAIKGRMDDLMRRRKEKQPLEYPSAGSTFKRPEGYFAAKLIEDSGLKGTHVGDAEVSIKHSGFLINKGKASAKDILDLIEVVKKTVKEKFNVELNTEVRIVGEESEN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_PSYA2
Sequence: MSKAPLALLSVSDKSNIVEFAQGLIQAGFGLLSTGGTFRLLTEHNVAVTEVSDYTGFPEMMDGRVKTLHPKIHGGILGRRGTDDMVMSEHAIERIDLVVVNLYPFAETIARSDVTMNDAIENIDIGGPTMVRSAAKNHAHVGIVTDPADYTRVLEALGDSTALTATLRYDLAVKAFEHTAQYDGMIANFLGSRVNESQEPESFSRTFNVQLEKVQDLRYGENPHQKAAFYVENNSSKSKQASIATAKQLQGKALSYNNIADTDAALECVKAFSTPACVIVKHANPCGVAVDIDQVAAYRTAFSTDPESSFGGIIAFNRPLTLAAATAIIDNQFVEVIIAPSVEDGVLEATASKKNVRVLVCGDLPAPELRDRQLDYKRVNGGLLVQEQDLGLITAHDLKIVTDVQPTEAQIADLLFSWNVAKYVKSNAIVYAKGQRTIGVGAGQMSRVNSARIAAIKAEHAGLATEGAVMASDAFFPFRDGIDNAAEVGIAAIIQPGGSMRDDETIAAANEHGIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: APT_XANC8
Sequence: MNDCSRCAGSTSSGPAHWSGRIRDIADFPKPGIVFKDITPLLSDGPDFASALDEMAQPWRTTPLDAVLGIEARGFILGAALARELRTGFVPVRKPGKLPGRTLIQEYALEYGTDRIEMHEDALPRGARVLIVDDVLATGGTLRAALGLAAQLELEIVGAAVLVELLALQGRSKWLNDVPLLATLSY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_ECOSE
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KITH_VZVO
Sequence: MSTDKTDVKMGVLRIYLDGAYGIGKTTAAEEFLHHFAITPNRILLIGEPLSYWRNLAGEDAICGIYGTQTRRLNGDVSPEDAQRLTAHFQSLFCSPHAIMHAKISALMDTSTSDLVQVNKEPYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPAEPPGTNLVVCTVSLPSHLSRVSKRARPGETVNLPFVMVLRNVYIMLINTIIFLKTNNWHAGWNTLSFCNDVFKQKLQKSECIKLREVPGIEDTLFAVLKLPELCGEFGNILPLWAWGMETLSNCLRSMSPFVLSLEQTPQHAAQELKTLLPQMTPANMSSGAWNILKELVNAVQDNTS
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: PLTP_MOUSE
Sequence: MVLLWALFLALLAGAHAELPGCKIRVTSAALDLVKQEGLRFLEQELETITIPDVYGAKGHFYYNISDVRVTQLHLISSELHFQPDQDLLLNISNASLGLHFRRQLLYWFLYDGGYINASAEGVSIRTGLQLSQDSSGRIKVSNVSCEASVSKMNMAFGGTFRRMYNFFSTFITSGMRFLLNQQICPVLYHAGTVLLNSLLDTVPVRSSVDDLVGIDYSLLKDPVVSNGNLDMEFRGAFFPLKEDNWSLPNRAVEPQLEDDERMVYVAFSEFFFDSAMESYFQAGALQLTLVGDKVPSDLDMLLRATYFGSIVLLSPTVINSPLKLKLEATSPPRCTIKPSGTTISITASVTITLAPPMLPEVELSKMIMEGRLSAKLTLRGKALRVKLDLRRFQIYSNQSALESLALIPLQAPLKTLLQIGVMPLLNERTWRGVQIPLPEGINFVREVVTNHAGFVTVGADLHFAKGLREVIDKNRPADVAASHVPPPSAAAA
What is the function of this protein?
Mediates the transfer of phospholipids and free cholesterol from triglyceride-rich lipoproteins (low density lipoproteins or LDL and very low density lipoproteins or VLDL) into high-density lipoproteins (HDL) as well as the exchange of phospholipids between triglyceride-rich lipoproteins themselves (PubMed:7654777, PubMed:7615508, PubMed:10079112).  Facilitates the transfer of a spectrum of different lipid molecules, including sphingomyelin, phosphatidylcholine, phosphatidylinositol, phosphatidylglycerol, and phosphatidyl ethanolamine (PubMed:10079112).  Plays an important role in HDL remodeling which involves modulating the size and composition of HDL (By similarity).  Also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion (By similarity).  Two distinct forms of PLTP exist in plasma: an active form that can transfer phosphatidylcholine from phospholipid vesicles to HDL, and an inactive form that lacks this capability (By similarity).
What are the official names of this protein?
Phospholipid transfer protein, Lipid transfer protein II.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Nuclear export is XPO1/CRM1- dependent.
Protein: Y146_NPVAC
Sequence: MNVNLYCPNGEHDNNISFIMPSKTNAVIVYLFKLDIEHPPTYNVNAKTRLVSGYENSRPININLRSITPSLNGTRGAYVISCIRAPRLYRDLFAYNKYTAPLGFVVTRTHAELQVWHILSVRKTFEAKSTRSVTGMLAHTDNGPDKFYAKDLMIMSGNVSVHFINNLQKCRAHHKDIDIFKHLCPELQIDNSVVQLETRSS
What are the official names of this protein?
Uncharacterized 22.9 kDa protein in IE0-IE1 intergenic region.
Protein: YAM5_CAEEL
Sequence: MATDADVIIEVILCIFLPPLAIWWHTKECDINVLIDIIFCLLFWLPGILYAVYICFFRK
What are the official names of this protein?
UPF0057 membrane protein C04G6.5.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUR7_BACC2
Sequence: MQKLELLYEGKAKRIYRTESADMVWVEYKDSATAFNGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHFVEKLSETEQLVKKVSIIPLEVVTRNVIAGSLSKRLGMEEGTVLAEPIVEFYFKDDDLGDPLVTEDHIRVLNVASPEQVSVLRDMALQINQVLIDHFASCRVRLVDFKLEFGVTEEGEIILADEISPDTCRLWDETSNEKFDKDVFRRDLGNLTEAYEEILKRLGGISHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: NLT2A_ORYSJ
Sequence: MARAQLVLVALVAAALLLAGPHTTMAAISCGQVNSAVSPCLSYARGGSGPSAACCSGVRSLNSAASTTADRRTACNCLKNVAGSISGLNAGNAASIPSKCGVSIPYTISPSIDCSSVN
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 2A, LTP 2A.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: RL14_CERS5
Sequence: MIQMQTNLDVADNSGARRVQCIKVLGGSHRRYASVGDIIVVSVKEAIPRGRVKKGDVRKAVVVRTAKEVRREDGTTIRFDRNAAVILNNQGEPVGTRIFGPVVRELRAKNFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PATM_PENEN
Sequence: MVDNYHSSLDVAKTPIQSDADAQKSEAETEGPSSKSSQIAAGESIADSVRNFLELRQGGIPDDTGVVFDKISAVGSGTGSQDAPTVTSAAQSAFGLLSPLQNRQRKQYSRPILSGFSGTINPGEMLLVLGKPGSGCTTFLKTLSGLWDEYKEIQGELTLGGHPLLDVMKQRPQDILFCAESDDHFPTLTVAETLRFATRARCGPQVSAREIDTMVTQLAKLVGLGNVLNTKVGDAKIRGVSGGERRRVSLAEALATCARLICLDNPTHGLDSSTAVEFMEMMREWTTQSRCVAAMSVYQASDAIVSYFDKVLIINSGRQIYYGPVRDAKAYFEDLGFECLSTTTVADFLNVMSADPDVRRAQENRENQVPRTAEEFERAFSASPIYQEMQKSVQVAKERFQTNPSPLVKTSAFALPIWHQIWYCAGRQFRIVTSDYSLWAVELATIVVQSLVLGTLFRNQQRTTSSLFIFASALFYSVLVPALQSMAEFGNGFAQRPLILKQKRYQISRPIAYALGLVTTDVVWKVAAICYNIPLYFLTGFQRTAGNFFTWFLIIYLEHLALSMFFRSVAIFSPNMHRAVLPVGIFFNMYVLYTGLYVPAPQMQVWLGWLRYLNPLYYAFESVMVNEFRDLSYQCSASDPVPSGLGYNDMAHQVCAVVGSEPGDRLLSGASYIHAQYGFKTSHLWRNVGINAALFVFFALCSGIGMEMLKTPAGQLATVFYKSSPGVTHRRDKIDSETGQDQGNESSEMSAGQSNDALRLQEHQGPDKSHNLAWTNLCLDIKTKEGDQRLLNNLSGSVKSGQLKALMGVSGAGKTTLLNALAGRSTIGNLTGTLALNGQVLPTFFRSRMGYVQQQDIHLPTQTVREALQMTARLRRPESISVADKNAYVEKVIEWLSMEHIADALVGVPGAGLNLEQRKKVSIGVEMASKPEILFLDEPTSGLDGQSAMLIARLLRRLADSGQAILCTIHQPAAELIDQFDKLYLLSRGGNLVYDGSLGTRCHEAIQYFQPRSRPCGPEENPAEYFLAVIGAGSRNDAHMDWASLWNDSEQGKEREKAEESLVPAAEQAPQLEQQSLYSVPFHVQLWVVVQRTWLYYWREPDYVNSKLWMSVGNSLLNSLTHLQSPNTERGAYNRVFSAFMSLIVGPPLGLQVQPRFVTLRDIFVHRERESLTYHWLAFVLSAFIVELPFTFLSSLVYWLLWYFPVGYFNAPSRAGYSFLMYELFGVFATSLAQLCASLMPNIEAAFAANGFFFMFCNTFAGTLSPKPVTPSGWRWFYNISPLFYLGEGVTVDVLQDLPIRCEESEVSIFYAVNGTTCGQYAQDFLKTATGYLLNPASTTECQYCRYRDGQSYFQQYGYEFAHRHRNIGVFICFIAFNFTMVLVMTYLTKTRRH
What is the function of this protein?
ABC transporter; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (Probable) (PubMed:30680886).  May be involved in the secretion of E-ascladiol to be converted to patulin by the secreted patulin synthase patE (Probable).
What are the official names of this protein?
ABC transporter patM, Patulin biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: J5_FOWPN
Sequence: MDNVINDEAIFKYCESNPKDRDCLCIHPEPTIEKIGEDLLLPYYCWYEPCKRKTAKIPTALRDNMKRCNLIDCSVSLGEINLLDGILKVNNDCLSSHAIYAGYSVKPLEQEIHLPIIDPKYLILGLAILALIVLINW
What is the function of this protein?
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.  Also plays a role in cell-cell fusion (syncytium formation).
What are the official names of this protein?
Protein J5 homolog, FPV136.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A16/G9/J5 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis (By similarity).
Protein: COXX_STAS1
Sequence: MNKEQTLAHNSSRVTFKELQQIIKMGLVQGNLIPAFAGSWLAIVLANHSFLSSIPQILMMLVGSTLIMGGACALNNYYDQDIDSIMPSKQQRPTVNERISNRNLLILSFGMMLIGEALLFALNIPSGVIGLLGIVGYVSFYSIWSKRHTVWNTVIGSFPGAVPPLIGWTAIEGNISLVAVALFLVIFCWQPIHFYALAIKRKDEYSLANIPMLPSVKGFNRTRVSMFFWLVVLLPLPFLLSSLGVTFIVLATLLNLGWLYLGLTSFKKDTDQTKWATKMFIYSLNYLVVFFVLVVVISLIQMF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAF_FLATR
Sequence: MSFTISTSFLQPLEISNLKSSPITSKSKVTSTSIVCSGSTDEKINNADGKSSLKALSAALALSSILVSSTVPALPASADISGLTPCKESKQFAKREKQSLKKLESSLKLYAPDSAPALAIKATMEKTKRRFDNYGKQGLLCGSDGLPHLIVSGDQRHWGEFITPGILFLYIAGWIGWVGRSYLIAIRDEKKPTQKEIIIDVPLATKLLFRGFSWPVAAYREYLNGELIDPTV
What is the function of this protein?
Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria).  This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
What are the official names of this protein?
Photosystem I reaction center subunit III, chloroplastic, Light-harvesting complex I 17 kDa protein, PSI-F.
What is the protein family that this protein belongs to?
Belongs to the PsaF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: RMLB_SALTY
Sequence: MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGAYQSWIEQNYEGRQ
What is the function of this protein?
Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
What are the official names of this protein?
dTDP-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: RUVA_BORHD
Sequence: MINKIYGKIIEKRESSIVIVALPFEFEVLVSSFCNAELRLLEDVEILTYLHLREDEIKLFGFLNVSEREVFEELISVDGIGPRAALRMLSGMKYDEFRDAIEREDVKRISTVKGIGNKVAGKIFLKLRGKLVKADELTSSVFKFKDLEQSIVNMGFDRKLVVAAIKEIMLIDEFLMLREVEQEQFLFRETLKRLSG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: VAPC_SHIFL
Sequence: MLKFMLDTNICIFTIKNKPASVRERFNLNQGKMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRIDVLDYDAAAATHTGQIRAELARQGRPVGPFDQMIAGHARSRGLIIVTNNTREFERVGGLRTEDWS
What is the function of this protein?
Ectopic overexpression in E. coli induces the YoeB toxin, but this is not the cause of VapC toxicity.
What are the official names of this protein?
tRNA(fMet)-specific endonuclease VapC, RNase VapC, Toxin VapC.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: OR2B6_HUMAN
Sequence: MNWVNDSIIQEFILLGFSDRPWLEFPLLVVFLISYTVTIFGNLTIILVSRLDTKLHTPMYFFLTNLSLLDLCYTTCTVPQMLVNLCSIRKVISYRGCVAQLFIFLALGATEYLLLAVMSFDRFVAICRPLHYSVIMHQRLCLQLAAASWVTGFSNSVWLSTLTLQLPLCDPYVIDHFLCEVPALLKLSCVETTANEAELFLVSELFHLIPLTLILISYAFIVRAVLRIQSAEGRQKAFGTCGSHLIVVSLFYSTAVSVYLQPPSPSSKDQGKMVSLFYGIIAPMLNPLIYTLRNKEVKEGFKRLVARVFLIKK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2B6, Hs6M1-32, Olfactory receptor 2B1, Olfactory receptor 2B5, Olfactory receptor 5-40, OR5-40, Olfactory receptor 6-31, OR6-31, Olfactory receptor OR6-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.