PharMolix/UniProtQA huggingface dataset:
Protein: YJ14_SCHPO
Sequence: MSISNQSGLDILREVDDEGQENSFLRKTTRKIQQFFKSDPGYQSRKAEYNSPAKATGDVNINVTSQDWLSKLDRNLSIENLTGKSLGIVVVSGRNKGLIKNPFLGGLVDIVMRRQDKLYLKSVEQVSSEYSPMQEQVYEFKVDMPLVQKRLGAFLKKNRVDGLSLSMHFSTGNYSLPVLIRHVLLYDYYTDDMKDSLWRAMIIYVSRQVTSNKYTKFHLWCVQKRIGNIRMYLVRPGDVYSFQGQTSWAAICNKSYMCNIQLEQSPEVSVKSSLPKYSNEPIFQSKTISQEEVGWLLFMLSIGNHARAFPIQNYLANTVMETVLPVELRCPFLSRSVDCEIFQKNTKRRVMEKWRQEFKKDLNVCEELEFKNVKKSGYMQPLFDLTMPLGCFDSLETKEMFYLRHNIAGFQADLTPYPMRI
What are the official names of this protein?
UPF0300 protein C737.04.
What is the protein family that this protein belongs to?
Belongs to the UPF0300 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGS1_MYCTU
Sequence: MNHLTTLDAGFLKAEDVDRHVSLAIGALAVIEGPAPDQEAFLSSLAQRLRPCTRFGQRLRLRPFDLGAPKWVDDPDFDLGRHVWRIALPRPGNEDQLFELIADLMARRLDRGRPLWEVWVIEGLADSKWAILTKLHHCMADGIAATHLLAGLSDESMSDSFASNIHTTMQSQSASVRRGGFRVNPSEALTASTAVMAGIVRAAKGASEIAAGVLSPAASSLNGPISDLRRYSAAKVPLADVEQVCRKFDVTINDVALAAITESYRNVLIQRGERPRFDSLRTLVPVSTRSNSALSKTDNRVSLMLPNLPVDQENPLQRLRIVHSRLTRAKAGGQRQFGNTLMAIANRLPFPMTAWAVGLLMRLPQRGVVTVATNVPGPRRPLQIMGRRVLDLYPVSPIAMQLRTSVAMLSYADDLYFGILADYDVVADAGQLARGIEDAVARLVAISKRRKVTRRRGALSLVV
What is the function of this protein?
Upon expression in E. coli functions as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA.  Prefers C(26:0)-CoA over C(18:1)-CoA.  TG synthesis activity increases in M. tuberculosis upon oxygen depletion and NO treatment, with concomitant accumulation of TG in inclusion bodies.  As disruption of the gene encoding this protein obviates TG synthesis this seems to be the major enzyme involved in production of TG.  Has no wax synthase activity to produce wax esters.
What are the official names of this protein?
Probable diacyglycerol O-acyltransferase tgs1, TGS1, Probable triacylglycerol synthase tgs1.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: F16PA_STUS1
Sequence: MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKAISHQVSKGALGGVLGSAGSENVQGEVQKKLDVLSNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDVNVSVGTIFSVLRCPDACFSQNDALGEEAFLQPGTKQVAAGYAIYGPQTMLVLTLGHGVMGFTLDRELGSFVLTHENLCVPQSTAEFAINMSNQRHWEAPVQRYVGELLAGKEGPLGKNYNMRWIASMVADVHRILTRGGIFMYPRDAREPDKAGKLRLMYEANPMSMIIEQAGGAATTGTQRILEIQPQSLHQRVPVFLGSKEEVERVTGYHQG
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
Protein: ITAM_HUMAN
Sequence: MALRVLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSEGGPPGAEPQ
What is the function of this protein?
Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PubMed:9558116, PubMed:20008295).  It is identical with CR-3, the receptor for the iC3b fragment of the third complement component.  It probably recognizes the R-G-D peptide in C3b.  Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1.  It recognizes P1 and P2 peptides of fibrinogen gamma chain.  Regulates neutrophil migration (PubMed:28807980).  In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407).  May regulate phagocytosis-induced apoptosis in extravasated neutrophils (By similarity).  May play a role in mast cell development (By similarity).  Required with TYROBP/DAP12 in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).
What are the official names of this protein?
Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Protein: NNRE_CAEBR
Sequence: MVHIISKKSVSFIGQSLAAKIDEQLFSKYGFKVEQLMELAGLASAQAIAAHYPKSKVAVLCGPGNNGGDGFVCARHLQQFGFNPSIVYPKESKNELMKSLVIQCETSSIPVQPNLPTDLQSFPLIVDALFGFSFKPPAREPFTEILKAVRASGIHVFSIDIPSGWDVENGAPSEASEDIIHPHAVISLTLPKMCMKSWTGPHFLGGRFVPRGLVEEHGLQMPVYPGFEQIVKVED
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: GVPG_HALMT
Sequence: MFLVDDLLVNPFLSLLDILHTMALDEMNDMEEIRDEIKENQLLYEIGERSETDYQQRKQQLEARLETAERIQAQMQGRIEVKR
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpG.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: CAT5_STAAU
Sequence: MTFNIINLETWDRKEYFNHYFNQQTTYSVTKELDITLLKSMIKNKGYELYPALIHAIVSVINRNKVFRTGINSEGNLGYWDKLEPLYTVFNKETENFSNIWTESNASFTLFYNSYKNDLIKYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNSRFLLPIITIGKFYSKDDKIYLPFPLQVHHAVCDGYHVSLFMNEFQNIIR
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: LSPA_SHESH
Sequence: MPTNWKDSGLRWYWVVVLVFIADQVSKQWVLTNFELHESVNLLPFFNFTYVRNYGAAFSFLSDAGGWQKWLFTFIAVAFSTILTIWLRKQPTKVWRLNLAYTLVIGGALGNLIDRLQHGYVVDFLDFFWNTSHFAAFNIADSAICIGAGLIILDSFIGDDKEKSQNGQNDNNAAKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELO_PSEU2
Sequence: MKALDELIFDNRFARLGDAFSTSVLPEPIDAPQLVVASQSALALLDLAPEQADLPLFAEIFSGHKLWSEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEVLHALGIPSSRAGCVVSSSTPVWRETQEHAAMVLRLAQSHVRFGSLEYFFYTKQPEQLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALAQALTPFISVDALREAIGLFLPLYQAHYLDLMRRRLGLTVAHEQDEQLVSQLLKLMQNSGVDYTLFFRRLGDQPAAEALRTLRDDFVDIKGFDGWAQAYQARIALENNGTEQERQTRMHAVNPLYILRNYLAQNAIAAAEKGDYAEVRRLHQVLCTPFTEQPGMQGYAQRPPDWGKHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SC22A_MOUSE
Sequence: MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQFPDRCTLKTGRYNINFISSLGVSYMMLCSENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQMEIKLRPPYQIPMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVAFILSLLCGALNLIRGFHAIESLLQSDGEDLNYIIAFFLGTAACLYQCYLLVYYTSWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDHDV
What is the function of this protein?
May be involved in vesicle transport between the ER and the Golgi complex.
What are the official names of this protein?
Vesicle-trafficking protein SEC22a, SEC22 vesicle-trafficking protein homolog A, SEC22 vesicle-trafficking protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NEP1_THESM
Sequence: MLHLIIADSELELVPKELQNHPSIISHAKRRFKKPEEILLDSTYHHTALKSLKDGERRGRPDIVHLCLINALESILNKEGKLRVYVHTRNNEVIYIKPETRLPRNYNRFVGLMESLFKNRVIPKDLALLRIENKTLSEIIGDIGPDAVFIMHENGVLMSPQSFGRKLNEYISPAVIVGGFPHGDFLSVLEGEKISIYKEPLMAWSVVNEVLINYEGSLLW
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: SMCO4_ANOGA
Sequence: MRKLRGGQTKETRKQRQERKEENLKIQQQMKTIVLPTIGVIFLCIVVYVFLKTRPRYEEL
What are the official names of this protein?
Single-pass membrane and coiled-coil domain-containing protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMCO4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CP2_APLCA
Sequence: MDSRICTSFARLMASALCVSTLLVTAMPFDLRRGSSDTDLDLQGHVDLGLDDLDKLRLIFPPGLIEEAFSQAQGKVDMPLPRQRTSSRSSERWAPKSKRFDFGFAGLDTYDAIHRALEQPARGTSNSGSGYNMLMKMQRHG
What is the function of this protein?
Mediates intrinsic neuromodulation.
What are the official names of this protein?
Neuropeptides CP2.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTL_SHIDS
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWTMAIMGIAVLMLSLFILKETRPAAPAASDKSRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAISLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAJ_BACCN
Sequence: MSKRDYYEVLGVSKSASKDEIKKAYRRLAKKYHPDVSKEENAVEKFKEVQEAYEVLSDEQKRAQYDQFGHAGSSQGFGGGDFGGGFGFEDIFSSFFGGGSRRRDPNAPRQGADLQYQVTLEFEEAIFGKELNVEIPVEDPCDTCHGSGAKPGTTKETCKYCSGTGQISVEQNTPFGRIVNRQTCRHCSGTGQMIKEKCTTCHGTGKVRKRKKINVKIPAGIDNGQQIRVAGKGEAGVNGGPAGDLYVVVHVREHEFFERDGDHIICEMPLTFAQAALGAEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTNLTAHQKELLREFAGQEDKDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_MACCJ
Sequence: MSQEKKVFKTEWAGRPLIIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDVDFFPLMVNYEEKLYAAGKIPGGFNKREGRPGEDATLTSRLIDRPIRPLFPKGYRHDVQVISIVMSVDPDNSPEMAAMIGSSMALAVSDIPFEGPIAGVNVGLVDGELIINPDVQQREVSVLDLQVAGHFDAVNMVEAGAKEVAEDKMLEAIMFGHAEIKKLVEFQQSIIDEIQPVKSEFVPVEVDADLESKVEQLSESFGLSQAIQTQEKLAREENITAIKLKVIEAFEGEDEAVITAVNKKFDALIKEEVRRLITEEKVRPDGRRPDEIRPLDSEVGILPRVHGSGLFTRGQTQALSVATLGALGEHQIIDGLGVEEEKRYMHHYNFPNFSVGETGPIRAPGRREIGHGALGERALLQVIPDEKEFPYTIRVVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTKDENYTILSDIQGMEDALGDMDFKVAGTKEGITAIQMDIKINGLTEDILREALEQARVGRLHIMEHMLSTISEPRAELSQYAPKIEIIHINPDKIRDVIGPGGKKINEIIDATGVKLDIEQDGTVFIGSSDASMIEAAKKLIENIVREAEVGQIYMATVKRIEKFGAFVEIFPGKDALVHISQIALERINKVEDVVKLGDQFLVKVTEIDKQGRVNASRKVLLEEEKKASEEK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDCA7_RAT
Sequence: MEARRARQKALKVKNLKNVRYMKLISVETSSSSDDSCDSFASDNFANTRLQFNREGCRTRSQCRPSGPLRVAMKFPARNTRRAANTKAAPPKPSESSANDSHSESDSEEEEDGMNFLEKRALNIKQNKAMLAKLMSELESFPGIFSGRHSLPGHRTKDSKSPRRRTFPGVASRRNPERRARPLTRSRSRILGSLGALPTEEEEDEEEEEDKYMLVRRRKSVDGYMNDDDVSRSRRPGSMTLPHIIRPVEDVTEEEIRNICSNSREKIYNRSLGSTCHQCRQKTTDTKTNCRNPDCWGIRGQFCGPCLRNRYGEEVKDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA
What is the function of this protein?
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells.  Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis.  May play a role as transcriptional regulator (By similarity).
What are the official names of this protein?
Cell division cycle-associated protein 7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-166 (By similarity).
Protein: CLPX_BORGP
Sequence: MARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLDSKSNGLPTPKQLKDHLDMHVVGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILLVGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAAHGDVSLAEKGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIEINTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLIPEFVGRLPVHSYLEKLNKEDLMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDEAILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKESVLNTDINPLILVGNAIKKPWAKELYEINLKYDKK
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ACCD_STAAC
Sequence: MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUV3_MOUSE
Sequence: MSLPRCTLLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLAASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLRHAKQIFPVLECKDDLRKISDLRIPPNWYPEARARQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERLTVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAINLVSELLYTTGEEVEVQKYERLTPISVLDHALESLDNLQPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGQVTTMHRDDLALLKDILNRPVDPIQAAGLHPTAEQIEMFAYHLPETTLSNLIDIFVDFAQVDGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSLVRSLQKELDAIIQEGVHNITKLIKISESRKLLNLESLPSGDQSRLSGASKSPARRTRGTKSAGNKATEPLSPSDKELPLASRLVQQGLLTADMLRQLQKEWLTQQPEHSREKVGTRRKKKDPDSD
What is the function of this protein?
Major helicase player in mitochondrial RNA metabolism.  Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner.  Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (By similarity).  ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction.  Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates.  Also implicated in recombination and chromatin maintenance pathways.  May protect cells from apoptosis.  Associates with mitochondrial DNA.
What are the official names of this protein?
ATP-dependent RNA helicase SUPV3L1, mitochondrial, Suppressor of var1 3-like protein 1, SUV3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Protein: GLYA_PSYA2
Sequence: MFKDISIKDFDPVLAKAMAAESVRQENHIELIASENYCSQAVMEAQGTDLTNKYAEGYPGKRYYGGCEHVDVVEQLAIDRAKELFGAEYVNVQPHSGSQANSAVFLALLEANDTVLGMSLDAGGHLTHGAHINFSGLNYNAVQYGLVEGTGLIDYDQVESLAKEHKPKMIIAGFSAYSQVVDWARFREIADEVGAYLLVDMAHVAGLIAGGVYPSPVPFADVVTTTTHKTLRGPRSGMILARDEKLAKKLNSAVFPGNQGGPLMHVIAAKAICFKEALENNFKTYQQQVVKNAQAMAKVIQERGYEIISGGTENHLMLISLVKQEMTGKEADKWLGDAHITVNKNAVPNDPKSPFVTSGIRIGTPAITTRGFNEAQAGALAGWICDVLDSRGDEAATAEVRSKVEAICKELPVYAKNQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL17B_MOUSE
Sequence: MDWPHSLLFLLAISIFLAPSHPRNTKGKRKGQGRPSPLAPGPHQVPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRPGPCRQRVVMETIAVGCTCIF
What is the function of this protein?
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
What are the official names of this protein?
Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: A85B_MYCTO
Sequence: MTDVSRKIRAWGRRLMIGTAAAVVLPGLVGLAGGAATAGAFSRPGLPVEYLQVPSPSMGRDIKVQFQSGGNNSPAVYLLDGLRAQDDYNGWDINTPAFEWYYQSGLSIVMPVGGQSSFYSDWYSPACGKAGCQTYKWETFLTSELPQWLSANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSALLDPSQGMGPSLIGLAMGDAGGYKAADMWGPSSDPAWERNDPTQQIPKLVANNTRLWVYCGNGTPNELGGANIPAEFLENFVRSSNLKFQDAYNAAGGHNAVFNFPPNGTHSWEYWGAQLNAMKGDLQSSLGAG
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85B, DGAT, 30 kDa extracellular protein, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex B, 85B, Ag85B, Extracellular alpha-antigen, Fibronectin-binding protein B, Fbps B.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_STRP4
Sequence: MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAITDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELTIPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKKKETPNKYPRKAGMPNKRPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH114_ARATH
Sequence: MTEEFEIAGISTGAWWSSPTNTAAVFSGYSLPCSTEISPDVTNFGWQNFDNKINDHNDGCMNMHNSFFEGLLIDPNDQLLPDPWSKSTIPNAKSELLENFPFLDNMFLVDSEAESLLDHEIRNHKSSKEQITQDYKNLTSKRSEELEENSDEYSPRLLKRPRLETLSPLPSFKVRKEKLGDRITALQQLVSPFGKTDTASVLNEAVEYIKFLQEQVTVLSNPEQNTIGSVQQQQCSNKKSINTQGEVEEDECSPRRYVDLSSRGLCLMPISASYPVAAAAASAAEMNVHLVSGIFHSL
What are the official names of this protein?
Transcription factor bHLH114, Basic helix-loop-helix protein 114, AtbHLH114, bHLH 114, Transcription factor EN 65, bHLH transcription factor bHLH114.