PharMolix/UniProtQA huggingface dataset:
Protein: MAMB9_DENVI
Sequence: RPYACELTVAAGPCLRFSAFYYSKGANQCYPFNYSGCGGNANRFSTNQKCRRTCVV
What is the function of this protein?
Interacts with vasopressin V2 receptor (V2R/AVPR2), probably in a selective manner (PubMed:35122240).  Inhibits vasopressin binding human V2R in the nanomolar range (Ki=45. 1 nM), and also potently inhibits vasopressin-induced cAMP production (IC(50)=111 nM) (PubMed:35122240).  In vivo, intraperitoneal injection of this protein into rats increases diuresis, without any loss of electrolytes (By similarity).
What are the official names of this protein?
Mambaquaretin-9, MQ9, Upsilon-Dv2b.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
Protein: ATPB1_GLUOX
Sequence: MSETLTPSAGAANNVVGRVTQVRGPVVDVQFEGDLPFILNALHVQNGDHTLVLEVAQEIGERQVRCIAMDTTDGLVRGTEVRDTGKQIMVPVGPATLGRILNVVGEPIDERGPISSELRFPIHRPAPSFEEQAAASEILVTGIKVVDLLCPYLKGGKIGLFGGAGVGKTVIIQELINNIAKAHGGVSVFAGVGERTREGNDLYFEMQDAGVIKIAEDGSTEGSKVALVYGQMNEPPGARSRVALTGLSLAEYFRDEEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPAATFAHLDATTVLNRSIAEMGIYPAVDPLDSTSRSLDPKIVGEEHYQVARQVQQTLQTYKGLQDIIAILGMDELSEDDKKIVGRARRIQRFLSQPFHVAEVFTGAPGKLVSLEDTIRSFKAVVAGEYDHLPEGAFYMVGDIDEAIAKAEKMKQEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CRCB_SALPB
Sequence: MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLGAFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLGSFAMTALAFWLFSAAAAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MARE3_MOUSE
Sequence: MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGGHEADAQILELNQQLLDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPVISGIIGILYATEEGFAPPEDDEIEEHQQEDQDEY
What is the function of this protein?
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton.  Promotes microtubule growth.  May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes.  Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement.  Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules (By similarity).
What are the official names of this protein?
Microtubule-associated protein RP/EB family member 3, EB1 protein family member 3, EBF3, End-binding protein 3, EB3, RP3.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Detected at the plus end of microtubules.
Protein: BMNL3_BOMOR
Sequence: MNFKYIVAVSILIASAYARSEENDIQSLSQRDVLEEESLREIRGIGAAILSAGKSALKGLAKGLAEHFGKRTAEDHEVMKRLEAAIHSLSQRDVLEEESLREIRGIGAAILSAGKSALKGLAKGLAEHFGKRTAEEHEMMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLYTKKEKRILGPILGLVSNALGGLLG
What is the function of this protein?
Has antimicrobial activity, but no hemolytic activity.  Preference on killing Gram-negative non-enteric bacteria.
What are the official names of this protein?
Bombinin-like peptides 3.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y404_METJA
Sequence: MKKIFIYPPNSLILTDLVERFGHKPLNLNIVIGKLVRNPEIDSPPMNITDEEPKKGLKYAAVEVPSGVRGRMALIGPLIEEAEAAIIMDDAPIAFGCIGCQRTNELTLYLVRRKNIPILRVKYPTNEEEAEILVNKIANFLKSLEENQEN
What are the official names of this protein?
Uncharacterized protein MJ0404.
Protein: CPD1_CANGA
Sequence: MSIALWYCPAPGTLDYEVLKTLINSLQLLVPGSPSFEPHLTVVTHLQVQNRGDVSKVLQSCSSCLKTIPKGHSLIKYSNWSINKQYFKKIVLECEKDKYLLSLAQLMRELYVEIEDQKRRAEHWVIEEFQPHVSLMYNDSQITKATEMVVRQRIHDAMQLFSNNPSSKSWRTFKVVSCEGPVEEWQVLGSVTL
What is the function of this protein?
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
2',3'-cyclic-nucleotide 3'-phosphodiesterase, CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. CPD1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: PSA3_BOVIN
Sequence: MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGEITNGRHEIVPKDVREEAEKYAKESLKEEDESDDDNM
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Binds to the C-terminus of CDKN1A and thereby mediates its degradation.  Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
What are the official names of this protein?
Proteasome subunit alpha type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: CARA_STRCO
Sequence: MTTSTRGAHRTPAVLVLEDGRIFRGRAYGAVGATFGEAVFSTGMTGYQETLTDPSYHRQVVVMTAPHVGNTGINDEDMESRRIWVSGYVVRDPARVPSNWRSTRSLDQELAAQGVVGISGIDTRALTRHLRERGAMRVGIFSGNALPDEGTMLAEVRQTPEMSGADLSAEVATTEAYVVPAIGEKKFTVAAVDLGIKGMTPHRMAERGIEVHVLPATATVDDVYAVEPDGVFFSNGPGDPATADHPVSVMQGVLERGTPLFGICFGNQILGRALGFGTFKLKYGHRGINQPVQDRTTGKVEVTAHNHGFAVDAPLDQVSDTPYGRAEVSHVCLNDNVVEGLQLLDRPAFSVQYHPEAAAGPHDAAYLFDRFVNLMEGQRA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: ATPE_PROMO
Sequence: MATFKLEVVTPLKKVLDRDAEMVIMRTIEGDMGVMADHAPFVAELAVGEMKIKSANGEEAYFVSGGFLEISKEKTMILADEAIDVKEIDVERAKREAEIAKETLVKLKEDKDIAVTQKSLQEALTKVRIAEQYMHHL
What is the function of this protein?
Produces ATP from ADP in the presence of a sodium gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, sodium ion specific, F-ATPase epsilon subunit, sodium ion specific, Na(+)-translocating ATPase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARMD3_XENLA
Sequence: MAQIEKKVGLLRKSSASKKPLKEKVVLMYDEIFTKEDPTKSNPRFWDELFLMKVNIEYLESKLESLDGEELMKLKDNINSLFQHCIHALRAEHQIRVVNSLQTLCALIRGVHQKNKPTSGFDIINMLMGFDKAELRMKNLMESLDLLLCGDGSESLKSLCLKLLLCLVTVTDNISQNTILEYVMINSIFEAILQILSNPLSRRQHGYDAVVLLALLVNYRKYESVNPYIVKLSIVDDENTLNGMGLVIARALFEYNRQYTDKEEENQTGFFSALTNMVGSMFIADADEKISVQTNEAILLALYEAVHLNRNFITVLAQSHPEMGLVAVPISPIPTTPTSPLGTTPPSSDVISPTELPMDADVQTSNLLITFLKYSSIVMQDTKDEHRLNSGKLCLIILTCIAEDQYANAFLHDDNMNFRVNLHRMPMRHRKKAADKNIPCRPLVCAVLDLMVEFIVTHMMKDFPMDLYTRCIQIVHKVLCYQKKCRVRLHYTWRELWLALINLLKFLMSNETVLLAKHNIFTLTLMVVNLFNMFITYGDTFLPTPSSYDELYYEIIRMHQIFDNLYSMVLRLSTNAGQWKEPASKVTHSLVNIRAIINHFNPKIESYAAVNHISQLSEEQVLEVVRSNYDTLTLKLQDGLDQYERYSEQHKEAAFFKELARSISINVRKNVAFNTLSQEILLKEFSTIS
What is the function of this protein?
May be involved in Golgi maintenance and protein secretion.
What are the official names of this protein?
Armadillo-like helical domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the ARMH3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein. Cytoplasm.
Protein: ZAPC_PROMH
Sequence: MIIKPDDRWRWYFDDEQQKLMLDLANGMIFRSRFPSKMLSATAHQSSPFTVDDAALYYGYDEQIRQIDMPSESRAELALNALIAHRFLKPLMPKSWYFEVSHSSTRPYLAQVVETALKDSNEKVLFLVAEVGEQACLCLLAQPQLALFDRTLTFCDPLKIMNDRLSEYHKQSEPRSFLYEKVI
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSY3_MAIZE
Sequence: MMSTSRAVKSPACAARRRQWSADAPNRTATFLACRHGRRLGGGGGAPCSVRAEGSNTIGCLEAEAWGGAPALPGLRVAAPSPGDAFVVPSEQRVHEVVLRQAALAAAAPRTARIEPVPLDGGLKAAFHRCGEVCREYAKTFYLATQLMTPERRMAIWAIYVWCRRTDELVDGPNASHISALALDRWESRLEDIFAGRPYDMLDAALSDTVARFPVDIQPFRDMIEGMRMDLKKSRYRSFDELYLYCYYVAGTVGLMSVPVMGISPASRAATETVYKGALALGLANQLTNILRDVGEDARRGRIYLPQDELEMAGLSDADVLDGRVTDEWRGFMRGQIARARAFFRQAEEGATELNQESRWPVWSSLLLYRQILDEIEANDYDNFTRRAYVPKTKKLMALPKAYLRSLVVPSSSSQAESRRRYSTLT
What is the function of this protein?
Catalyzes the conversion of geranylgeranyl diphosphate to phytoene.  Mediates the first committed step in carotenoid biosynthesis.  May play a role in regulating carotenoid flux in response to abiotic stress in roots.  May control flux to carotenoid precursors that are required for abiotic stress-induced abscisic acid (ABA) formation in roots.
What are the official names of this protein?
Phytoene synthase 3, chloroplastic, ZmPSY3.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule.
Protein: ATPL_THEMA
Sequence: MENLGDLAQGLALLGKYLGAGLCMGIGAIGPGIGEGNIGAHAMDAMARQPEMVGTITTRMLLADAVAETTGIYSLLIAFMILLVV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBN_SYNP2
Sequence: MDSATVLSIGIAVVVIAVTGFSIYTAFGPPSVELEDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: EFTU_NEIMB
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAALTTILAKKFGGAAKAYDQIDNAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFMNKCDMVDDAELLELVEMEIRDLLSSYDFPGDDCPIVQGSALKALEGDAAYEEKIFELAAALDSYIPTPERAVDKPFLLPIEDVFSISGRGTVVTGRVERGIIHVGDEIEIVGLKETQKTTCTGVEMFRKLLDEGQAGDNVGVLLRGTKREDVERGQVLAKPGTITPHTKFKAEVYVLSKEEGGRHTPFFANYRPQFYFRTTDVTGAVTLEEGVEMVMPGENVTITVELIAPIAMEEGLRFAIREGGRTVGAGVVSSVIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_AZOVD
Sequence: MDKLIITGGHRLDGEIRISGAKNAALPILAATLLADTPVTVCNLPHLHDITTMIELFGRMGVQPVIDEKLSVEMDASSIKTLVAPYELVKTMRASILVLGPMLARFGEAEVALPGGCAIGSRPVDLHIRGLEALGAQIEMDGGYIKARAPAGGLRGGHFFFDIVSVTGTENIMMAAALASGRTVLENAAREPEVVDLANFLIGMGAQIKGAGTDTVVIEGVKRLGGGRYSVMPDRIETGTYLVAAVATRGRVKLKDTDPTILEAVLLKLEEAGAQIDTGNNWISLDMKGNRPKAVNVRTAPYPAFPTDMQAQFISMNAVAEGTGTVIETVFENRFMHVYEMNRMGARILVEGNTAIVTGVPCLKGAPVMATDLRASASLVIAGLVAEGDTLIDRIYHIDRGYECIEEKLQLLGAKIRRIPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD1_CANAL
Sequence: MPLKPISFRWSKTSVRSVPNPFMYGPDNLNKPLSRASQMAERVHQQTPSSTNYQQRRYFSYYYYQFPKIPRPKRNMLYYSTWSRNPVTNASNANKPSKRHMLPFGSFKISKRSFANANQKLKTKLKKLKMGKERRRFIRWWTVTSLTIVLGGVYAKIKYERGDHEENPYKIRPQSWHLYAYSALPLKTISRLWGQVNSINLPVWIRSPSYRVYSAIFGVNLDEMENPDLSSYKNLSEFFYRDIKPDARPIADGDLVSPADGKVLKFGVVENGEIEQVKGMTYSIDALLGIDTGKLAAPTHSLNFDYNSDDETIVKRDEEFAKINGISYSMDDLVGGNSKSTYHMNELTYKDEHDGTAAGERASFSKELRVAEELTPNPVEYFRKKNLYFAVIYLAPGDYHHFHSPTSWVTTLRRHFIGELFSVAPFFQKTLQGLFVLNERVALLGYWKYGFFSMVPVGATNVGSIVVNFDKDLKTNDIYEHEVYSSASSVNESTPLLDQKDYSANDILTITNSEYEDKKRKKLRKNTVYEATYTNASRLLGGYPLSKGQDIGGFKLGSTVVLVFEAPENFKFNLKVGEKVKVGQSLGGFV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity).  Important for virulence (PubMed:20132453).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
[Phosphatidylserine decarboxylase 1 beta chain]: Mitochondrion inner membrane; Single- pass membrane protein; Intermembrane side. SUBCELLULAR LOCATION: [Phosphatidylserine decarboxylase 1 alpha chain]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.
Protein: IF4E3_XENTR
Sequence: MALPAAPADRRLQPEPDEQLHLNHRELGELALPQEPDTEGIPLHSPWTFWLDRSLPGTTAAECESNLKKIYTVHTIQSFWSVYNNIPQVTNLPLRWSYHLMRGERKPLWEEESNAKGGVWKMKVPKEASSLVWKELLLATIGEQFTDRCAPEDEVIGVSVSVRDREDVVQVWNGNASVVGEATVLEKIYELLPNTSFKAVFYKPHEEHHAFEGGRSRH
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E type 3, eIF-4E type 3, eIF-4E3, eIF4E type 3, eIF4E-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
Protein: PSME1_PIG
Sequence: MAALRVQPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEDKDEKKKGEDEDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTALHTKLEGFHTQISKYFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity).
What are the official names of this protein?
Proteasome activator complex subunit 1, Proteasome activator 28 subunit alpha, PA28a, PA28alpha.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: C1RL_RAT
Sequence: MCWLLLWGILHTCPTQASVLLAQQFPQQLTSPGYPEPYIKGQESHADIEAPEGFAVRLIFQDFDLEPSPGCEGDSVTISTRGTDATRLCGQQGSSLGSPPNQMEFVSSGRSLRLTFRAHSSKNKVTHLHKGFLALYQAAVSQPNGDAEAFTTPGANPPEIQNHCPGPYYKEEQTGTLSCPSSRKWKDRQRGEEVPECVPVCGRPVVPIAENPNTFGSSRAKPGNFPWQAFTSIYGRGGGALLGDRWILTAAHTIFPKDSIYLRKNKTVNVFLGHTDVDELLKLGNHPVRRVVVHPDYRQEESHNFDGDIALLELEHRVPLGPSLLPVCLPDNETLYHSGLWGYISGFGVEMGWLTTKLKYSKLPVAPREACEAWLRQRQRTEVFSDNMFCVGEEMQVNSVCQGDSGSVYVVWDDRALRWVATGIVSWGVGCGKGYGFYTKVLSYVDWIKGVIECKDRCPEA
What is the function of this protein?
Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
What are the official names of this protein?
Complement C1r subcomponent-like protein, C1r-LP, C1r-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_ALKCK
Sequence: MRQDGRKQNQLREVEIIPHFTKHAEGSVLISVGDTKVICTASIENRVPPFLRGQNKGWLAAEYSMLPRATGQRTIREAAKGKLSGRTMEIQRLIGRALRAVVDLEKLGEKTIWIDCDVIQADGGTRTASITGAYVALVLAVQKAFAEKTISAWPITDFLAAISVGILPEEGAVCDLCYSEDSQAKVDMNIVQTGSGDFVEVQGSGEEAVYTRSELNELLDLAAEGIDQLIHIQRPFLGEAASWIEEKKGT
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MVP_CMVN
Sequence: MAFQGTSRTLTQQSSAATSDDLQKILFSPEAIKKMATECDLGRHHWMRADNAISVRPLVPEVTHGRIASFFKSGYDVGELCSKGYMSVPQVLCAVTRTVSTDAEGSLRIYLADLGDKELSPIDGQCVSLHNHDLPALVSFQPTYDCPMETVGNRKRCFAVVIERHGYIGYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNIESSQYVLTNAKINQNARSESEELNVESPPAAIGSSSASRSEAFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: COAT_ELV
Sequence: MTSSRSTELIETQEDVVRKLSQKTPVSNFSALPLPNGPQAPTQLQPFQFEFPLPAGQEGSVTLPLATFPKMATFLSRHRRAQLTQLHAVVSPSAVSIGHPLTVQLIWVPASSTTTSSQILGTYGGQQISVGGQVTNSSPAKVSANLLMMNPHIKDSTSYTDTPKLLVYSTPAVPDDKLTTSSASIIVFGEVLLSSPQLNPSA
What are the official names of this protein?
Coat protein, Virion protein.
What is the protein family that this protein belongs to?
Belongs to the tymoviruses coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ISPH_YERPA
Sequence: MQILLANPRGFCAGVDRAISIVERAIEMYGAPIYVRHEVVHNRYVVESLCERGAIFIEEISEVPDGSILIFSAHGVSQAVRAEARSRNLTMLFDATCPLVTKVHMEVARASRKGKEAILIGHAGHPEVEGTMGQYSNPNGGMYLVESPDDVWQLNVKDENNLCFMTQTTLSVDDTSAVIDALNTRFPKIVGPRKDDICYATTNRQEAVRNLANDADIVLVVGSKNSSNSNRLAELVQRMGKPAYLIDSAADIQEFWLQGAKCIGVTAGASAPDILVQQVIARLKDLGAGESIELSGREENIVFEVPKELRVEVKQID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CRN8_PHYIN
Sequence: MVTLFCAVVGVAGSTFPVDINENKSVGHLKKAIKEEKMYQFPADELQLFLAKAGGNAWLSSLTEDVKKLKKGEKTALVKSLTQEEKELQGEDPISECLEGMDPPKVKQIHVLVALPPGTSSAPISDGTDLWLSRFQHSEVAKLTLLPTRGDLNEFIGQPLPVKIGLPQSVFQAWSSPLILGQLLRDKLFELNDISPCEFLKDSVFSAAFLYPQVDGDATESAFHYFWDSIIRVVLGFVFRRAYVNRDSSRKSSSGLKRPDFLFALDHICVFRGEEKEPRTSITVPREELSKKLVWSYGGVPYVFGYAASGFELELFAIYQDVTGNVKTHLIGGFNLQHAPERFRLVLALLNLCLLFPAIVQNCPASAGTEFMDIHRANGVKVRLSPIFVDKIFHTQEEYRRVKQIYDSLKAYGVPCADAVVTVDSDQLRLTLKPRGIEMKPCSLSELFVALGNVLEALVVLHRNGWMHRDIRWSNVIKHIDRVEWFLIDFADAAQSPQKYPSGDHLTHDEHASDIFMEGGSHTTAVDLWAVGYLVKTSKIEREWTAEPERALFLDRLMNPDPSARPTADEALQLLSRFEREAAEQESQGKGVRKKHRRA
What is the function of this protein?
Secreted effector that induces cell death when expressed in host plants (PubMed:19741609, PubMed:22927814, PubMed:20847293).  Acts as a kinase and is able to autophosphorylate, however its cell death inducing-abiliy is not a direct result of its kinase activity, but rather a consequence of the phosphorylated state of the five identified serine residues in the CRN8 protein (PubMed:22927814).
What are the official names of this protein?
Crinkler effector protein 8.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: TRS20_YEAST
Sequence: MPQYFAIIGKKDNPVYEIEFTNAENPQGFPQDLKELNPFILHASLDIVEDLQWQINPTSQLNGNGGNGSNGGGGFLRSRAVNNTDNCYLGKVDHFYGLAITAYISYSGMKFVMIHGNSANSSVVIDDNNMRSFYQEVHELYVKTLMNPFYKITDPIRSPAFDSRVRTLARKHLSK
What is the function of this protein?
Component of the TRAPP I, TRAPP II and TRAPP III complexes which act as guanine nucleotide exchange factors (GEF) for YPT1.  TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.  TRAPP II plays a role in intra-Golgi transport.  TRAPP III plays a role in autophagosome formation.
What are the official names of this protein?
Trafficking protein particle complex subunit 20, TRAPP subunit 20, Transport protein particle 20 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum. Preautophagosomal structure.
Protein: VKIL_LAMBD
Sequence: MPLQGGLLLAALPNLYLNESPVNYVTDGNALSTYLISQESQRMDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILILKLRSSKSIH
What is the function of this protein?
Gene kil kills the host upon prophage induction.
What are the official names of this protein?
Protein kil.
What is the protein family that this protein belongs to?
Belongs to the lambda phage kil family.