PharMolix/UniProtQA huggingface dataset:
Protein: XPC_HUMAN
Sequence: MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL
What is the function of this protein?
In absence of DNA repair, the XPC complex also acts as a transcription coactivator: XPC interacts with the DNA-binding transcription factor E2F1 at a subset of promoters to recruit KAT2A and histone acetyltransferase complexes (HAT) (PubMed:29973595, PubMed:31527837).  KAT2A recruitment specifically promotes acetylation of histone variant H2A. Z. 1/H2A. Z, but not H2A. Z. 2/H2A. V, thereby promoting expression of target genes (PubMed:31527837).
What are the official names of this protein?
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125.
What is the protein family that this protein belongs to?
Belongs to the XPC family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Omnipresent in the nucleus and consistently associates with and dissociates from DNA in the absence of DNA damage (PubMed:18682493). Continuously shuttles between the cytoplasm and the nucleus, which is impeded by the presence of NER lesions (PubMed:18682493).
Protein: PA_I00A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERSESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLNIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTGQLKWALGENMAPEKVDFEDCKDVSDLRQYDSDEPESRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAVGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIAQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RS11_BACVZ
Sequence: MAAARKQNTRKRRVKKNIESGIAHIRSTFNNTIVTITDTHGNALSWSSAGALGFRGSRKSTPFAAQMAAETAAKGSIEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYD_ECOBW
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP2_BORHE
Sequence: MRKRISAIIMTLFMVFMSCNNGGPELKSDEVAKSDGTVLDLAKISKKIKDAVEFAASVKEIETLVKSIDELAKTIGQKLTKDTGVLAADANNNNGGLIAGVYGIVTDVGTKLDGLLKVNGISEDIKTKINDSKSKGTAFLSKVKGDDDLCKKDATDAHAKNAIDKNDNTGGKGKTELIALNTAIDELLKAANEAVEAAIKELTAPVKAEKPSQNN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable small protein 2.
What is the protein family that this protein belongs to?
Belongs to the variable small protein (Vsp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PTH_SHEB8
Sequence: MSEIKLIVGLANPGAEYAHTRHNAGAWYVLELARICGVTLVADSKYFGLTARAVLHGKDVRLLIPTTYMNLSGKAVGALANFFRITPEEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIIAKLANDKNFYRLRLGIGHPGDKNQVSGYVLGKAPAKEQELIDAAIDEAVRSTEILFKQDMVKAMNRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_HELPJ
Sequence: MDFINIEKKWQEFWWKNKSFEPKDDFNLPKKYILSMLPYPSGEIHMGHVRNYTIGDALARYYRLHHYNVLHPMGFDSFGMPAENAAIKHGIHPKTWTYENIEAMQKEFEALGFSFSKNREFATSDPDYTKFEQQFFIDLWEKGLIYRKKAMLNWCPNDKTVLANEQVIDGRCWRCDTEVIQKELYQYYLKITNYAEELLKDLETLENHWPSQVLTMQKNWIGKSSGLQFGFKIADECLKACNNIQEIEVFTTRADTIYGVTYIAIAPEHPLVEHAIKRVSQEDSKMIKAILNTTQRERALEKKGAFLGIYAIHPLTKQKIPVWVANFALANYGSGALMGVPACDERDFEFANLYHIPIKVITQSPQNLPHTKEEILKNSGEWSDLSSSVAREKIIAYFEKENLGKRVINYRLQDWGVSRQRYWGAPIPMIHCKHCGIVPETQLPVTLPEDIVIDGEGNPLEKHASWKFAQCPKCHKDALRETDTMDTFIQSSWYFLRYTTPKNQRENQAFDQNYLKYFMPVDTYIGGIEHAILHLLYARFFTKALRDLGYLHLDEPFKQLITQGMVLKDGAKMSKSKGNVVSPKEILKKYGADAVRLFILFAAPPAKELEWNDNALEGAHRFIKRLYDKANAITPTTSKPEFKEVGLNEAQKLARKKVYEALKKSHEIFNKAESAYAFNTLIASCMEALNALNAQSDEQILCEGYFVLLQILEPMIPHTAWELSERLFKRENFKPIEVDESALIEDFMTLGLTINGKRRAELKVNINASKEEIIILAKKELEKYLENASVKKEIYVPNKLVNFVTA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAK20_ORYSJ
Sequence: MSVQEDDDAAGPEVDRLRRHDSFYGDAEKVSNDKSHGTGENWARTLQLAFQSIGVVYGDVGTSPLYVYSSTFPDGVKHPDDLVGVLSLMLYTLILIPMVKYVFIVLYANDNGDGGTFALYSLISRHAKIRMIPNDQTEDANVSNYSIEAPSSQLRRAEWVKQKLESSNAAKIALFTITILGTSMVMGDGTLTPAISVLSAVSGIREKAPSLTQLQVVWISVPILIVLFSVQRFGTDKVGYSFAPVISVWFVLIAGIGAYNLAVHEITILRAFNPMYIIDYFRRNGKEAWVSLGGAVLCITGTEAMFADLGHFNIRAIQLSFTCVLFPSVALCYMGQAAYLRKFPEDVGDTFYKSLPAPLFWPVFVVAIMAAIIASQAMLSGAFAILSKALPLGCFPRVEVVHTSNKYEGQVYIPEVNFLIGVASVAITVAFQTTANIGNAYGICVVMVFSITTHLMTVVMLLIWKVRLPFIAAFYVVFTFTEFLYLSSILSKFAEGGYLPFCFSLVLMALMATWHYVHVKRYWYELDHIVPPDEMAALLARRDVRRVPGVGLLYTELVQGIPPVFPRLVDKIPSVHAVFVFMSIKHLPIPRVAPAERFIFQRVGPDAGHRIFRCVARYGYTDPLEGAKEFAAFLLDRLKVFVYEEAVFACQCAEDGGGGGGGDDDGVLRRAEEMAAEEKRLIDAEAERGLVYLMGEANVEAAPGSSLMKQIVVNYVYTRLRKNLREEHKALSIPKDQLLKVGITYEI
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Potassium transporter 20, OsHAK20.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLMM_ACET2
Sequence: MGRLFGTDGVRGVANLELTAELAYKLGQAGAYVLTSETKHTPKILVGMDTRISGDMLEASLVAGLCSVGAEVACLGIAPTPTVAYLTRYYNADAGVVISASHNPYEFNGIKFFNSKGYKLSDALEERIESIILDNSEKIQLPTGEKIGRKIEIESPLDDYVNFIKSTIKGDLKGLKVAIDCANGASYQVAPVTFFELGADVCVINNEPDGVNINKDCGSTHIEQLQKFVIESGADVGLAFDGDADRVLAVDENGNMVDGDQIMAIIGLELKKQGKLTNNTIVATVMSNLGLDIMAKREGINIVKTKVGDRYVLENMLENGHVLGGEQSGHIIFLEHSTTGDGILTGAQLLNVVKSSGKKLSELASIMQVLPQVLMNARVSNQNKEKYLEDEVICEMCKELENEFRDEGRVLIRPSGTEPLVRVMIEGKDRDYIEKRALELVKVIEERLG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DAPA_PHEZH
Sequence: MIDPMFRGVLPALVTPYRNGQVDEDAFVALVERQIAGGVHGLVPVGTTGESATLTHEEHRRVVELCVKTARGRVPVVAGAGSNSTAEAIELVRHAKTVGADAALVVTPYYNRPSQEGLYAHYRAINDAVQLPILVYNVPTRTSVDISNDVLVRLSKLPNVVGIKDATSDLVRASFQRLHCGEEWVMLSGDDPVALGYMAHGGHGCISVTANVAPEQCADFYNAALSGDWATALQWQDRLVRLHKALFADASPAPTKFALSHLGLCSEETRLPITPASEAARAEVLAAMRDAGLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_ECO27
Sequence: MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAAQAFHLTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPAEVAYGA
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_CHLTB
Sequence: MSNALPKGVFDIFPYVTSPKNLWRNSSLWKRVEHAAHRICNLYGFDEIRTPVFEKTETFLRVGEHSDIVKKEVYTFLDKKGRSLTLRPEGTAAVVRALLDHSADMRKDNKFYYILPMFRYERQQSGRYRQHHQFGLEAIGVRHPLRDAEVLSLLWDFYAAVGLQHMQIHVNFLGGQKTRARYDEALREFFRKDLDRLSPLSQERYHANLLRILDSKEPEDQEFIEKAPSILDYIDDRDLSYFDAVLAQLKALGIPFAINPRLVRGLDYYTDLVFEAVTVVGERSYALGGGGRYDELVAQSGGPSMPAFGFGVGLERVIQTLLEQGNSLSTSTRRLRLIPMDEQADAFCFSWANRLRNLGIATEVDWSHKKPKLSLKDAADQQVSFVCLLGEQELATKQFIVKDMSLHQSFSGAQQDVEQRLVYEVQNA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_PSEAE
Sequence: MVQSAPASEIAALILRGFDDYREQFREITDGARARFEQAQWQEAQRASAQRINLYEEKVAETVAGLRAGLADSELLDVERWPIIKSAYIAQIDLRLDDELAETWFNSIFCGLFSHDNISDGTMFVHTTRPSLRAHARAPYTRTYRPGGDLRQALEKIFDDYRFDVPYDDRERDLERIDALLHSNLPDWVCKDPDLAIELIGSVFYRNKGAYLVGRLFTPDEQWPLVFPLLHREDHGIQFDTVITDEAEVSIIFSFTRSYFMVDVPVPAELVAFLKRLLPGKHLAELYTSIGFYKQGKSEFYRALINHLATTDDRFVMAPGVRGMVMSVFTLPGFNTVFKIIKDRFNPSKSVDHATVIQKYQLVKNHDRVGRLADTQQFADFRFPVSKFEPECLAELLEVAPSTVVMEGDVVLIRHCWTERRMTPLNIYLENASEAQTREALNDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEICYLTEVNFRYIPEPRFPEDEMSSEPWYSVGPNDVFPEEFPRFLFVDLNQRRLFAKLHGNLYDAKYWQGLQEQIREGKVIDVFPYRRQETPEQLLG
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DKGB_SALTI
Sequence: MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQNRKVVDWAKAHGIHITSYMTLAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSVIPSSTRRENLASNLLAQDLHLDAEDKNAIAALDCNDRLVSPEGLAPAWD
What is the function of this protein?
Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
What are the official names of this protein?
2,5-diketo-D-gluconic acid reductase B, 2,5-DKG reductase B, 2,5-DKGR B, 25DKGR-B, AKR5D.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFP69_HUMAN
Sequence: MPQQLLITLPTEASTWVKLQHPKKAVEGAPLWEDVTKMFEGEALLSQDAEDVKTQRESLEDEVTPGLPTAESQELLTFKDISIDFTQEEWGQLAPAHQNLYREVMLENYSNLVSVGYQLSKPSVISQLEKGEEPWMAEKEGPGDPSSDLKSKIETIESTAKSTISQERLYHGIMMESFMRDDIIYSTLRKVSTYDDVLERHQETCMRDVRQAILTHKKRVQETNKFGENIIVHSNVIIEQRHHKYDTPTKRNTYKLDLINHPTSYIRTKTYECNICEKIFKQPIHLTEHMRIHTGEKPFRCKECGRAFSQSASLSTHQRIHTGEKPFECEECGKAFRHRSSLNQHHRTHTGEKPYVCDKCQKAFSQNISLVQHLRTHSGEKPFTCNECGKTFRQIRHLSEHIRIHTGEKPYACTACCKTFSHRAYLTHHQRIHTGERPYKCKECGKAFRQRIHLSNHKTVHTGVKAYECNRCGKAYRHDSSFKKHQRHHTGEKPYECNECGKAFSYNSSLSRHHEIHRRNAFRNKV
What is the function of this protein?
Putative transcription factor that appears to regulate lipid metabolism.
What are the official names of this protein?
Zinc finger protein 69 homolog, Zinc finger protein 642.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAND_ANADF
Sequence: MRRTFFKSKIHRATVTHADLDYEGSVSIDEDLLDASGILEYEAVHVWNITRGTRLQTYAIKGERGSGVICINGAAAHLNKPGDLVILATFAELDEAEARGFKPTVVLVDRKNKIVESDAVEIAGPARRVSA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_PARP8
Sequence: MSTPYLLIDAGNSRVKWALVQADGTQTHSGAFSHGGQLVKGTGDPLQSRHEPDWSALPAPGSAWLSNVAGDAVARRIDAFIDRHWPGLARTTVRSAAQQCGVTNAYTTPSQLGSDRWAGMIGARAAFPGEPLLIATFGTATTLEALTADGVFVGGLIAPGWSLMMRSLGEHTAQLPTLDSTAARGLLDGDNAAGQREPAERGAWFATDTPRSLSSGCALAQIGLIERMWRHLQDEWQVSVRLVVGGGAAGELVQALSVPYTRHDSLVLAGLALIAAQAPVYPSTHTRPV
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DISA_BACCR
Sequence: MEENKQRVKSMINILQLVAPGTPLREGIDNVLRAQTGGLIVLGYNEQIKSIVDGGFHINCAFSPASLYELAKMDGALILNETGSKILIANAQLVPDSSIDSIETGMRHRTAERVAKQTGSLVVAISQRRNVITLYQGNLRYTLKDIGVILTKANQAIQTLEKYKAVWNDGITNLGILEFEEVVTMSEVVHVLHSVEMVLRIKNEILSYIHELGTEGRLIRLQLTELLADLEAEAALLIKDYHQEKTQDHHQILKKLQDLANTQLLEDSDLVKLLGYPGQTSLEESVTPRGYRITSKISRVPPLIIENLINRFKTLQGVCRATINELDDVEGIGEVRAKKIREGLKRIQEHLYMSRHN
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: Y2308_CERS1
Sequence: MAGHSKWANIQHRKGKQDKLRSKMFSKLAKEITVAAKMGDPDPDKNPRLRLAVKAAKAVSMPKDVIERAIKKSQGGDAEDYSEIRYEGYGPNGIAIIVETMTDNVNRTASNVRSYFTKYGGNLGTTGSVSFMFDRVGEITYKPEAGDADTVMMAAIEAGADDVESDEEGHWIYCGDTSLNEVSEALEKVLGESEEAKLVWKPQNRTNVDLETAQKLMKLIDALEEDDDVQTVTGNFDIPEDVAAKLDA
What are the official names of this protein?
Probable transcriptional regulatory protein Rsph17029_2308.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_PEDPA
Sequence: MINGTALILGALVTLVGMPQFINYFRVRNEGQMIREEGPKWHQKKSGTPTMGGMVFIIAIIIASLVTGVIFHGAKVSLLMLLFVLVEFGLIGCWDDSIKLLKRQNEGFKAWQKLLGQIIGGLIFFLVIKETGVALQLNIPGLGIWHLGGWYALFVIFWLTGFSNAVNLSDGLDGLVAGLSTIAFGTYAIIAAHQQNIPVMIFCMAVVGSMLGFLVFNHKPAKIFMGDMGSLALGGALAAVSILLNQELSLILIGIVFVLETLSVILQVLSFKLTGHRIFKMSPIHHHFEMLGWSEWKVDIVFWIVGLIGSIITLISIL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NP04_EHV1V
Sequence: METCSPPVTFITYALYGIKTSPAWTLPNFEQVICSCDWGYRLIAVGAESKCDVTPQGSFVIQHGASITALVLDCGVEFCSYAFTHAENTRVPLTTEDGSVLVVPFCGWVCVGRDRCLRSMSGGVLTISWDTSQTAYISVAVYRPPTLQCHALDCTRAETTVCSTAAITDASESDPLYADQEGDQTQDQDGGHDFLETILMESDLYGTNGASALLEPCFPCLSNND
What are the official names of this protein?
Nuclear protein UL4 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL4 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CIMH_BACSU
Sequence: MGELQTHMQLQTDTIHEGVRKENWFAKAMNIKVGIIPLPVYALLFILITVFVMHHDVKSDILTSIAVMAFFGFTFAQIGKSIPIVRSIGGPAILATFIPSAVVYYHLLPNDIVKSTTEFTENSNFLYLFIAGIVVGSILGMKRETLVKAFMKIFIPLIVGSVTAAIVGLAVGTLLGLGFQHTLLYIVIPIMAGGVGEGAIPLSIGYSDIMPISQGEAFALVLPSIMLGSLCAIILAGLLNRIGKKKPEWTGNGKVDRSEEESPALEESQSGQQMFNLSLFASGGILAVSLYLVGMLAHDFFGFPAPVAMLLLAVLIKLFRLVPASIENGAFGVSRFFSTAVTYPLLFAIGVSMTPWDKLVAAFNLSNIITILSVVVTMMAVGFFTGKWLNMYPIETAIINACHSGQGGTGDVAILSAAERLELMPFAQVSTRIGGAITVSLTLLLLHQFY
What is the function of this protein?
Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate.  Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions.  Is strictly stereoselective, translocating only the (S)-enantiomer of malate.
What are the official names of this protein?
Citrate/malate transporter, Citrate/malate-proton symporter.
What is the protein family that this protein belongs to?
Belongs to the sodium:citrate (SCF) symporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCDA_METJA
Sequence: MKIMFLGNDTVEIKDGRFFIDGYDAIELAEKFGTPLYVMSEEQIKINYNRYIEAFKRWEEETGKEFIVAYAYKANANLAITRLLAKLGCGADVVSGGELYIAKLSNVPSKKIVFNGNCKTKEEIIMGIEANIRAFNVDSISELILINETAKELGETANVAFRINPNVNPKTHPKISTGLKKNKFGLDVESGIAMKAIKMALEMEYVNVVGVHCHIGSQLTDISPFIEETRKVMDFVVELKEEGIEIEDVNLGGGLGIPYYKDKQIPTQKDLADAIINTMLKYKDKVEMPNLILEPGRSLVATAGYLLGKVHHIKETPVTKWVMIDAGMNDMMRPAMYEAYHHIINCKVKNEKEVVSIAGGLCESSDVFGRDRELDKVEVGDVLAIFDVGAYGISMANNYNARGRPRMVLTSKKGVFLIRERETYADLIAKDIVPPHLL
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: RK16_CHLVU
Sequence: MLSPKRTKYRKHHRGRMRGKASRGNTVVFGDYALQSLEASWITSRQIEAARRAMTRQVRRGGQIWIRLFPDKPVTMRPAETRMGSGKGAPEFWVAVVRPGKVLYELKGVPESVARVALRLAASKLPVKTQILVK
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK20_HUPLU
Sequence: MTRVKRGSVARKRRKNILKLASGFQGAHSTIFRTGNQQIIKALASSYRDRGKRKRDFRRLWITRINAAARNNGVSYTKFIRHLYKNQVSSNRKVLAQIAIFDTNSFSTILKKLSSGESIRYRNFSPEFYSGEVRTP
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCSH_SODGM
Sequence: MSNVPTELKYTASHEWVLNEGDGVYCVGITEHAQELLGDMVFMDLPEVGATFSAGEDCAVAESVKAASDIYAPISGEIVAVNDDLEASPELVNSAPYTDGWLFKIKATDDSEVNELLDAAAYQAAIDEEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.