PharMolix/UniProtQA huggingface dataset:
Protein: GATB_BURM7
Sequence: MTQWEVVIGLETHAQLSTVSKIFSGASTQFGAQPNTQACPVDLALPGVLPVLNRGAVERAIRFGLAIGATVAPRSVFARKNYFYPDLPKGYQISQYEIPVVQGGQITIQVPANEKAGKQAYSKTVNLTRAHLEEDAGKSLHEDFAGMTGIDLNRAGTPLLEIVTEPEMRSAAEAVAYAKALHGLVMWLGICDGNMQEGSFRCDANVSVRPVGQEKFGTRAEIKNLNSFRFLEDAINYEVRRQIELIEDGGEVVQETRLYDPDKRETRSMRSKEDAHDYRYFPDPDLMPLVIGADWIARVKGEMPELPAVMQQRFIEQYGVSAYDAGVLTSTKAMAEYFEALVAKAGAANAKLAANWLMGDVSSQLNRDGIDIDACPVSAAQLALVLQRIADGTISNKIAKEIFVTIWDEKAADEGAADRIIEAKGLKQISDTGALEAIIDEVLAANAKSVEEFRAGKDKAFNALVGQAMKATKGKANPQQVNELLKKKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: KR134_MACFA
Sequence: MSYNCCSGNFSSRSFGGYLHYPGCNPYSTALCSPSICQLGSSLYRNCQKTCWEPTSCRKSCYRRRTSMLCSPCQTTCSRSLGFGSSSCHSQGYGSRSCYSLGSGSSGFRFLKYGGCGFPSLSYGSRFCYPNYLASRAWQSSCYRPICGSRFYQFTC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 13-4.
What is the protein family that this protein belongs to?
Belongs to the PMG family.
Protein: HIS7_BUCAP
Sequence: MKQKILFIDRDGTLIHEPSNDCQVDAINKLEFKKYIISSLCQLMNFGYKFVMVTNQDGLGSKSFPRENFNIPHFFMLNIFRSEGIIFEDVLICPHFLDDNCDCRKPQTKLLKPWLKKNKIDKQRSYVIGDRETDMELAKNINLTGIQYKEKEFNWIDITKEIIKRNRYREVIRETKETYIHIKLWLDLEHHSCIQTGINFFDHMLEQLSIHSGISMYILAKGDLQIDDHHTIEDTGIVLGEALSQALNNKNGLSRYGFVLPMDESQAKCIIDLSNRPYLSFNAHFKHKMVGDMNTDMVEHFFYSLCCSMKITLHIDVKGKNDHHCIESLFKAFGRALRKAVKIEGNTLPTSKGIL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_LISW6
Sequence: MAKKSKVVKHERQKALVEQYAELRRTLKAEGRYEELRKLPRDSTPSRLHNRCALTGRPHGYMRKFGMSRIRFRELAHQGQLPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: AROB_HAEI8
Sequence: MLCVNVELQERRYPILIGSGLLQDERSYPIKRGDRVMIVTNPTVAQFYLDTVIYALEKRGCVVDHVLLPDGEKYKTLESLNLIFTALLQDNHGRDTTIIALGGGVIGDVAGFVAASYQRGVRLIQMPTTLLSQVDSSVGGKTAVNHELGKNMIGAFYQPSMVIIDTLTLNTLPKREVNAGLAEVIKYGAILDYEFFEWLEQHIDELVALHPEALQHCISRCCQIKADVVARDETEKGDRALLNLGHTFGHAIETHLGYGNWLHGEAVSTGMMMAAVLSEELGDISIADVSRLEKLLARANLPTVSPDTMQPEDYLPHMMRDKKVLSGKLRLVLLKSLGQAYVANDTDHTLVLNAIRRCTQTD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1639_YERPB
Sequence: MRNMMSLCWQYLRAFTIIYLCLWAGKALALLLPIVIPGSIIGMLILFVLLTLQILPSPWVKPSCQLLIRYMALLFVPIGVGVMQYYEQLTKQFGPIVVSCFISTLIVMLVVAYSSHYVHRDRKVISPSTPTEGEK
What are the official names of this protein?
UPF0299 membrane protein YPTS_1639.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YEBG_ECOLI
Sequence: MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTNSPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA
What are the official names of this protein?
Uncharacterized protein YebG.
Protein: ATPE_SALPC
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKAEEHIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL32_NEOSM
Sequence: MPVPKRKTSPSRRGKRRSHDGLRPENVIVNKTTGEFQRSHHVSLDGFYNGRRVLSPKGKAGSS
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DAPF_ALKOO
Sequence: MDVQFKKMQGTGNDFIVVKYDDFPFEEKLSQLAEKICDRHFGIGADGLLIVNPSSIADIRMDYYNSDGSIAAMCGNGIRCFSKFVFDEGFLRTKQFSVETLDGIKEIAIIEEKGTVKSVEVNMGQVTYDTEKIPVVSEDGYFINKKITVGGQDFIITAVSMGVPHVIIFTEKLDLEQIKFFGPLIEKHAIFPKKTNVNFVHRIDKDNIAVRTWERGAGYTLACGTGSTSAVAVANKLGLVNNNVNVEVEGGNIKIKIKESGNLFMEGPAENICSGRFFFN
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP37_ORYSJ
Sequence: MNAAVLLLLLALAALPASCAPPRSFRLELASVDASAADAANLTEHELLRRAIQRSRYRLAGIGMARGEAASARKAVVAETPIMPAGGEYLVKLGIGTPPYKFTAAIDTASDLIWTQCQPCTGCYHQVDPMFNPRVSSTYAALPCSSDTCDELDVHRCGHDDDESCQYTYTYSGNATTEGTLAVDKLVIGEDAFRGVAFGCSTSSTGGAPPPQASGVVGLGRGPLSLVSQLSVRRFAYCLPPPASRIPGKLVLGADADAARNATNRIAVPMRRDPRYPSYYYLNLDGLLIGDRAMSLPPTTTTTATATATAPAPAPTPSPNATAVAVGDANRYGMIIDIASTITFLEASLYDELVNDLEVEIRLPRGTGSSLGLDLCFILPDGVAFDRVYVPAVALAFDGRWLRLDKARLFAEDRESGMMCLMVGRAEAGSVSILGNFQQQNMQVLYNLRRGRVTFVQSPCGALR
What is the function of this protein?
Anther-specific aspartic protease involved in tapetal programmed cell death (PCD).  Directly regulated by the transcription factor EAT1/DTD in anthers during tapetum PCD and degeneration.
What are the official names of this protein?
Aspartyl protease 37.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: RBL_XANFL
Sequence: MGADAAIGQIKDAKKRYAAGVLKYAQMGYWDGDYQPKDTDILALFRVTPQDGVDPVEAAAAVAGESSTATWTVVWTDRLTAADMYRAKAYKVEPVPGQPGQYFCWVAYELDLFEEGSIANLTASIIGNVFSFKPLKACRLEDMRLPVAYVKTFRGPPTGIVVERERLDKFGRPLLGATTKPKLGLSGKNYGRVVYEGLKGGLDFVKDDENINSQPFMHWRDRFLYCMEAVNKAQAETGEVKGHYLNITAGTMEEMYRRADFAKELGSVVVMVDLIVGWTAIQSISNWCRENDMLLHMHRAGHGTYTRQKGHGISFRVIAKWLRLAGVDHLHTGTAVGKLEGDPMTVQGYYNVCREDVTRTDYTRGIFFDQDWAGLRKVMPVASGGIHAGQMHQLIDLFGEDVVLQFGGGTIGHPDGIQAGAIANRVALETMILARNEGRDIKNEGPEILVEAAKWCQPLRAALDTWGEVTFNYASTDTSDFVPTASVA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: FLGD_SALTI
Sequence: MSIAVNMNDPTNTGVKTTTGSGSMTGSNAADLQSSFLTLLVAQLKNQDPTNPLQNNELTTQLAQISTVSGIEKLNTTLGAISGQIDNSQSLQATTLIGHGVMVPGTTILAGKGAEEGAVTSTTPFGVELQQPADKVTATITDKDGRVVRTLEIGELRAGVHTFTWDGKQTDGTTVPNGSYNIAITASNGGTQLVAQPLQFALVQGVTKGSNGNLLDLGTYGTTTLDEVRQII
What is the function of this protein?
Required for flagellar hook formation.  May act as a scaffolding protein (By similarity).
What are the official names of this protein?
Basal-body rod modification protein FlgD.
What is the protein family that this protein belongs to?
Belongs to the FlgD family.
Protein: KATG_ECOL5
Sequence: MSTSDDIHNTTATGKCPFHQGGHDQSAGGGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ARL5A_HUMAN
Sequence: MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
What is the function of this protein?
Lacks ADP-ribosylation enhancing activity.
What are the official names of this protein?
ADP-ribosylation factor-like protein 5A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: MAFA1_NEIM0
Sequence: MKTLLLLIPLVLTACGTLTGIPAHGGGKRFAVEQELVAASSRAAVKEMDLSALKGRKAALYVSVMGDQGSGNISGGRYSIDALIRGGYHNNPESATQYSYPAYDTTATTKADALSSVTTSTSLLNAPAAALTKNSGRKGERSAGLSVNGTGDYRNETLLANPRDVSFLTNLIQTVFYLRGIEVVPPEYADTDVFVTVDVFGIVRSRTELHLYNAETLKAQTKLEYFAVDRDSRKLLIAPKTAAYESQYQEQYALWMGPYSVGKTVKASDRLMVDFSDITPYGDTTAQNRPDFKQNNGKNPDVGNEVIRRRKGG
What are the official names of this protein?
Adhesin MafA 1/2.
What is the protein family that this protein belongs to?
Belongs to the MafA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PURL_CAMC5
Sequence: MDKATIKAHKINEQEYEEILKILGREPNLLELGIFSAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDVGGGVAAVFKMESHNHPSFIEPFQGAATGVGGILRDVFTMGARVVANMNSLRFGEVCGDSENARKQRYLLKGAVAGIGHYGNCMGIPTVGGETTFDASFNGNILVNAFALGLVKSDEIFYGKAEGIGNPVIYVGSKTGRDGLGGAVMASDSFSDANKSLRPTVQVGDPFAEKLLMEACLELFKKDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKMQLDRVPMREEGMSPYELMLSESQERMLICAKKGCEQKVLEIFKKWDLDAEVIGEVTDSGQMQLYWHGELVGQIPIKPLSEAAPVLDRPTARPKYLDEIKNLQIPKDIDNKTAFLKLLRESEILNKALIYDQYDANIQTNTIKQPGYLGAAVIRIKETGKALAMAAQCDPRANFVGPKIGAARAVAAAGRKVAMSGAMPLAITDCLNYGNPQNPEVMWQFAQGCEGIKEACRELNTPVVSGNVSLYNDTDGVSVYPTPAIVSVGVNDDARANLKSVFGSAGTAIYLLGETKGEFAASLYVKALFDVVGGTLSEIDYKKERALWELVIAANKAGVLEFANSVGVGGVAMSLAKMACISGIGAECKFDVAQANFIFDESFSRALVGVTSEAKFSELAAKFGVKFEKIGVTGGDKFRLNEIDENLKEISEIYFNEFANIIKQED
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXR1_ELSFA
Sequence: MSGRRRRLTESVSTRVGSYHVADAVALQREGAAMVVGIDILLTWNGSLPFSLGDLRFLHCVRSERRSCGKSLPGMNSSRVNMAETSGISAFTQFWGCIRLDGSCEVTRRPAMDLHGHHYREAYLQPAIMDGPCTGASSSARGRDGKKALIHRLLAALCPVRCPAKISGSSVRPMLAASRISGPVRSFIASCRRQDEQMNGRSQMRDCARRAFLPLRVSDARSEWICFIVAIW
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of elsinochromes, pigments consisting of at least four interconvertible tautomers (A, B, C and D) that have a core phenolic quinone to which various side chains are attached and which play an important role in fungal pathogenesis (PubMed:18957608).  The non-reducing polyketide synthase PKS1 was proposed to iteratively catalyze decarboxylation between acetyl-CoA and malonyl-CoA subunits for polyketide chain elongation.  The released polyketide undergoes cyclization to form an aromatic ring, and proceeds via serial modification steps to produce the heptaketide back- bone of elsinochrome.  As elsinochrome has a symmetrical structure, two identical heptaketides are fused to form a core 1,2-dihydrobenzo-perylene ring structure, which can then be successively modified to produce the various derivatives of elsinochrome.  Some of these reactions may be cooperatively carried out, at least in part, by the products of RDT1, OXR1 and PKS1.  PRF1, embedded within the elsinochrome cluster possibly functions to stabilize some of the biosynthetic enzymes required for elsinochrome production.  As prefoldin is a hexamer containing 2 a and 4 b subunits, additional prefoldin subunits, whose coding genes may not immediately link to the elsinochrome biosynthetic gene cluster, are required to fulfill the chaperone function.  In addition, no methyltransferase-coding gene exists within the biosynthetic gene cluster, even though elsinochrome has four methyl groups at positions C3, C7, C8 and C12.  Apparently, the identified gene cluster does not contain the entire entourage of genes responsible for elsinochrome biosynthesis.  Once elsinochrome is synthesized, it must be exported outside the fungal cells, which is probably accomplished by the ECT1 transporter, to avoid toxicity (PubMed:21199563).
What are the official names of this protein?
Oxidoreductase 1, Elsinochromes biosynthesis cluster protein TSF1.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: YO18_ADEG1
Sequence: MSALSSCFNGSDSRWDPPYPKADVRRLMGTYSPDFPSWPKLIVWWNETFLTFSDGPWVVSQMRRLGVLDGKDSGELIILVQDMYPDVCPLINRARYDGTYKWTSEMMRKILRMHTIMTPESPVILLDWTNQLRDICKKVDALLWGQDVRGPAYYAVRTTAHFFTEFKDHRIHCIGMSLGGTVCAALSRQLLVRTEGQKRLAA
What are the official names of this protein?
Uncharacterized protein ORF18.
Protein: OLF2_CANLF
Sequence: MDGKNCSSVNEFLLVGISNKPGVKVTLFITFLIVYLIILVANLGMIILIRMDSQLHTPMYFFLSHLSFSDARYSTAVGPRMLVGFIAKNKSIPFYSCAMQWLVFCTFVDSECLLLAVMAFDRYKAISHPLLYTVSMSSRVCSLLMAGVYLVGIMDASVNTILTFRLCFCESNVINHFFCDVPPLLLLSCSDTQVNELVIFTIFGFIELITLSGLFVSYCYIILAVRKINSAEGRFKAFSTCTSHLTAVAIFQGTMLFMYFRPSSSYSLDQDKIISLFYSLVIPMLNPLIYSLRNKDVKEALKKLKNKKWFH
What is the function of this protein?
Putative odorant or sperm cell receptor.
What are the official names of this protein?
Olfactory receptor-like protein OLF2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4436_PSEP1
Sequence: MLTVISPAKTLDYDTPPVTERFTLPQYLDESQALIQQLRELSPAQISELMHLSDKLAGLNAARFGSWTPDFTPVNAKQALLAFKGDVYTGLDAENLSDDDFSYAQDHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANARGKDLYAFWGTRISEWLNQALADQGDDVLLNLASNEYFSAVKRSALKARVINVDFKDQKNGQYKIISFYAKKARGMMSRFVIQQRISTPDQLKQFDAQGYYYSAEQSKPDHLVFLRDHPSE
What are the official names of this protein?
UPF0246 protein Pput_4436.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: CH60_STAA8
Sequence: MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYFLVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_RUBXD
Sequence: MKSYMARPGEVERKWYVIDAEGKTLGRLAAEISRLLRGKNKPQYTPHVDVGDFVVVVNADKVEVTGRKAEQKVYRWHTGYPGGLRERSYRQMLRKRPEEILRQAVRGMMPKTRLARRQLKKLRIYAGPEHPHAGQTPEPYEVR
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CST10_MOUSE
Sequence: MASLLSPSMPVLAAVALTLTLAVIPEASTNAEAKQVVLGGVEPADPKDKEVQKVVKFAVRTYNDMDNDLYLSKPIRLMSASQQVVAGKNYYLKIELGRTTCTKTESNLVDCPFNEQPDQQKRVICNFQINVAPWLNKMSMTNFNCYNF
What is the function of this protein?
May play a role in the last steps of the chondrocyte differentiation pathway as an inducer of maturation (PubMed:13679380).  Induces chondrocyte calcification during endochondral ossification by playing a role in the transcriptional inhibition of ENPP1, a generator of pyrophosphate which inhibits calcification (PubMed:16680148).  Possibly impairs the binding of a transcription factor to the ENPP1 promoter (PubMed:16680148).  Unlike other cystatins, does not have thiol protease inhibitor activity (PubMed:16680148).
What are the official names of this protein?
Cystatin 10, Carminerin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HME2A_XENLA
Sequence: MEENEQNNREVEPQQESGEESNRGILHQAPPGNHQPHHRITNFFIDNILRPEFGRRKEGISHQDELYTERDTGALSGAESGHHRVNVPEGAGGSSKVITVTGEKKSDLAMEETLKSRGLNGDHSLSSDSDSSQTSSKATQQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKSVSKEDKRPRTAFTADQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNSLALHLMAQGLYNHSTTSKDGKSDSE
What are the official names of this protein?
Homeobox protein engrailed-2-A, En-2A, Homeobox protein en-2-A, En2 1.4.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NEC1_HHV7J
Sequence: MAIQSTRRLRRASSLLKKSKPYNKEKTNLSLSLSLKELHSVFKLFPEYELKFLNMMKLPITGKEPIKIPFDLSLHHQHTCLDLSPYANEQVSKSACVNCGTTNIPTASDAMVAYMNQISNVMQNRLYYYGFQKKVELIRMSAKQPTLFQIFYILSSIASNFLPIMFENNEKLNMYVVFQTRTLHIPCECINQIMTVSSGYTVLLDILHDSIVLHVLCKTIETSNIQIDINVLQRKIEEMDVPDEIGDKFEKLKHILPFI
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC1 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane. Note=Remains attached to the nucleus inner membrane through interaction with NEC2.
Protein: TMED1_XENTR
Sequence: MAWSSSFLFIVLPLAAAVAVQPQDTELTFLLPAGRQECFYQTTLYNGSMEIEYQVIGGAGLDVDFSVTTPSGILLIMERRRSDGVHTVEPTEAGDYMICFDNSFSTISEKLVFFELIFDNQQGDEEPDSWADVVEPDELLDIKLEDIKESIESVKSRLERSIQMQTVLRAFEARDRNLQDSNLERVNFWSAINVGVLVTVAFLQVYMLKSLFDDKRKIRT
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.  Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1.  Plays also a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 1, p24 family protein gamma-1, p24gamma1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
Protein: KO1_GIBIN
Sequence: MNKSNSMNNTSLERLFQQLVLGLDGIPLMDVHWLIYVAFGAWLCSYVIHVLSSSSTVKVPVVGYRSVFEPTWLLRLRFVWEGGSIIGQGYNKFKDSIFQVRKLGTDIVIIPPNFIDEVRKLSQDKTRSVEPFINDFAGQYTRGMVFLQSDLQNRVIQQRLTPKLVSLTKVMKEELDYALTKEIPDMKDDEWVEVDISSIMVRLISRISARVFLGPEHCRNQEWLTNTAEYSESLFITGFILRVVPHILRPFIAPLLPSYRTLLRNVSSGRRVIGDIIRSQQGDGNEDILSWMRDAATGEEKQIDNIAQRMLILSLASIHTTAMTMTHAMYDLCARPEYIEPLRDEVKGVVDASGWDKTALNRLHRLDSFLKESQRFNPVFLLTFNRIYHQSMTLSDGTNLPSGTRIAVPSHAMLQDSAHVPGPTPPTEFDGFRYSKIRSDSNYAQKYLFSMTDSSNMAFGYGKYACPGRFYASNEMKLTLAILLLQFEFKLPDGKGRPRNITIDSDMIPDPRARLCVRKRSLRDE
What is the function of this protein?
Catalyzes three successive oxidations of the 4-methyl group of ent-kaurene giving kaurenoic acid, a key step in gibberellin (GA) biosynthesis.
What are the official names of this protein?
Ent-kaurene oxidase, Cytochrome P450 503A1, Cytochrome P450-4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RAS_LENED
Sequence: MAGRTTFLREYKLVVVGGGGVGKSALTIQFIQSHFVDEYDPTIEDSYRKQCVIDDEVALLDVLDTAGQEEYGAMREQYMRTGEGFLLVYSITSRNSFEEISTFHQQILRVKDQDTFPVVVVANKCDLEYERQVGMNEGRDLARHFGCKFVETSAKVRINVDQAFQDLVREIRKYNKEQQTTGRMMTGGGGGGPPGTYAGKDPNDEGAGGCCGGCVVL
What are the official names of this protein?
Ras-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.