PharMolix/UniProtQA huggingface dataset:
Protein: VGP_MABVP
Sequence: MKTTCLFISLILIQGIKTLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNIRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGRVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSNNGTQTNDTGCFGALQEYNSTKNQTCAPSKIPSPLPTARPEIKPTSTPTDATTLNTTDPNNDDEDLITSGSGSGEQEPYTTSDAVTKQGLSSTMPPTPSPQPSTPQQEGNNTDHSQGTVTEPNKTNTTAQPSMPPHNTTAISTNNTSKNNFSTLSVSLQNTTNYDTQSTATENEQTSAPSKTTLPPTGNLTTAKSTNNTKGPTTTAPNMTNGHLTSPSPTPNPTTQHLVYFRKKRSILWREGDMFPFLDGLINAPIDFDPVPNTKTIFDESSSSGASAEEDQHASPNISLTLSYFPNINENTAYSGENENDCDAELRIWSVQEDDLAAGLSWIPFFGPGIEGLYTAGLIKNQNNLVCRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLTRWGGTCKVLGPDCCIGIEDLSRNISEQIDQIKKDEQKEGTGWGLGGKWWTSDWGVLTNLGILLLLSIAVLIALSCICRIFTKYIG
What is the function of this protein?
GP2 acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in GP2, releasing the fusion hydrophobic peptide (By similarity).
What are the official names of this protein?
Envelope glycoprotein, GP1,2, GP, Virion spike glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[GP2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In the cell, localizes to the plasma membrane lipid rafts, which probably represent the assembly and budding site. SUBCELLULAR LOCATION: [GP1]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=GP1 is not anchored to the viral envelope, but forms a disulfid-linked complex with the extravirion surface GP2. In the cell, both GP1 and GP2 localize to the plasma membrane lipid rafts, which probably represent the assembly and budding site. GP1 can also be shed after proteolytic processing.
Protein: AAMDC_BOVIN
Sequence: MSSPEIASLSWGQMKVQGSTKIYKDCKVWPGGSRDWDWRETGTEHSPGVQPADVEEVVEKGVQILVIGRGMSEALKVPPSTVEYLKKKGIDVRVLQTEQAVKEYNALATQGIRVGGVFHSTC
What is the function of this protein?
May play a role in preadipocyte differentiation and adipogenesis.
What are the official names of this protein?
Mth938 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the AAMDC family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Diffuse distribution with some highly concentrated spots around the nucleus.
Protein: DED1_SCLS1
Sequence: MADQLNMNGLNLNGGEPRSYIPPHMRGKMGGPAPAGPPANLNGSAWAPQGNGYANGPRPAGGDSWANAPDFTPRGNGAPRGGNNWNPSGPPSFNKNAYGNPAAGAGGPGSAGGAGGAGGGAGQARGGGDGQWRDGKHIAGPANARLERELFGIADDPTKQQTGINFEKYDDIPVEASGQDVPEPVLKFTNPPLDDHLIKNIELAHYKVPTPVQKYSIPIVMGGRDLMACAQTGSGKTGGFLFPILSQAFQTGPSPIPANAAGSFGRTRKAYPTSLILAPTRELVSQIFDESRKFAYRSWVRPCVVYGGADIGSQLRQMERGCDLLVATPGRLVDLIERGRISLQNIKYLVLDEADRMLDMGFEPQIRRIVEGEDMPGVQNRQTLMFSATFPRDIQMLARDFLKDYVFLSVGRVGSTSENITQKVEYVEDIDKRSVLLDILHTHGAGLTLIFVETKRMADSLSDFLINQNFPATSIHGDRTQRERERALEMFRNGRCPILVATAVAARGLDIPNVTHVVNYDLPTDIDDYVHRIGRTGRAGNTGISTAFFNRGNRGVVRDLIELLKEANQEIPAFLENIAREGAGFGGGRGGRSGGRGRGGGANRDFRKFGGGGGGGFNGGGGFGGPPASGGYGGGGGFGGPPAPASYGPPPGQYGGGGYGGGGGAYGNPSAGGGQSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase ded1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_CAEEL
Sequence: MFRTITSRLAFSVRQAEETVKPRIAYAQRSGRRIKEKVALMQAKRKEAGETGAPEKPGKFVLKTGKGTRDYGPAQSALRNSVLQTVTETFNRYGAETIDTPVFELRDVLMGKYGEEGGKLVYDLQDQGGELLSLRYDLTVPFARYLAMNKITNITRYQIAKVYRRDQPVMSRGRYREFYQCDFDIAGQYDLMLPEAECLGIVDELLTKLEIGEFFINLNHRLILEGMFAVSGIPAKDFKTICSSVDKLDKTPWEDVEQEMINEKFLTKEQTGKLGELVRFRELNSDLNNLELLEKMSQLPDLGQNDKFKKGAEELKVLIEYLNVDGVTTVRYEPSLARGLDYYTGAIYEAVAPKALEGTAVENSEDTAGQPVGVGSVAAGGRYDGLVKMFDSKANVPCCGVSFGIERLFAIMEARQKVAIRTTQTEVYVASAQKNLVRDRKKLVKMLRSAGIKTEMALKANPKLLTQFQYAEERRIPLAIVIGEQELKDGVVKLRNVVTRDEQTIKLDQLITAVRDTLAAL
What is the function of this protein?
Involved in protein synthesis (PubMed:23076791).  Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (Probable).  Required for germ cell development (PubMed:21464306).
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: GLYA_DESVH
Sequence: MDELLLQDPEVGKAIILEIERQTGKLELIASENFVSAAVRQAQGSVLTHKYAEGYPGKRYYGGCEFVDIAENIAIERARTIFGCEYANVQPHSGSQANMGVYFACLKPGDTILGMNLSHGGHLTHGSPVNFSGRLFNVVFYGVEKETGRIDYEQVAALAREHKPSLIVAGASAYPRTIDFARFRAIADEVGAKLMVDMAHIAGLVAAGYHPSPVQHAHYTTTTTHKTLRGPRGGMILSTEDNGKTLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPAFKEYQKQVVDNAAALAGVLTAAGFDLVSGGTDNHLMLVDLTSKDVTGKDAEIALDKAGITVNKNTVPFETRSPFVTSGVRLGTPALTTRGMKAAEMEKVGGWIVDAIANTTNETRLAEISREVERFARQFPLFAW
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP1A1_CHACA
Sequence: MALMILPFIGSVSVSESLVALTAVCLVYLILKFFRTEIPAGLRQLPGPKPLPIIGNVLEVGSKPHLSLTAMSKRYGDVFQIQIGMRPVVVLSGSETVRQALIKQGDEFSGRPDLYSFTFINDGKSLAFSTDQAGVCGACRKLAYSALRSFSTLDGTTPEYSCMLEEHICKEGECLINQLNTVMKADGSFDPFRHIVVSVANVICGMCFGRRYDHNDQDLLRLVNLSDEFGQVAGSGNPADFINILRFLPSTTMKKFMTINADFNTFVKKIVGEHYATFDKNNIRDITDSLIDHCEDRKLDENCNVQMSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAYPDIQERLFQEIKDNVGLDRTPLLSDRSKVPYLEAFILELFRHSSFLPFTIPHCSAKDTSLNGYFIPKDTCVFINQWQINRDPELWKDPSSFNPDRFLSCNGTEVNKQEGEKVMVFGMGKRRCIGEVIARNEVYRGLAILIQRLQFHEMPGELLDMTPEYGLTMKHKRCHLRATMRARNEQ
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: ATPG_PSEU2
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQMRMAASRPYAERIRQVIGHLANANPEYRHPFMIERPVKRVGYVVVSSDRGLCGGLNTNLFKTLVKDMAVNRENGVEIDLCVVGSKGAAFFRNFGGNVVAAISHLGEEPSINDLIGSVKVMLDAYLDGRIDRLSVVSNKFINTMTQQPTVEQLIPLVATPDQGLKHHWDYLYEPDAKELLDGLMVRYVESQVYQAVVENNAAEQAARMIAMKNATDNAGDLISDLQLIYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFTS_CAMHC
Sequence: MQITAKMVKDLRESTGAGMMDCKKALVEANGDMEQAIKVLHEKGLGKAAKKADRLASEGLVCVLVNSDFSKATISEINSETDFVAKNDKFINFVNNTTKHIQDSNITNVEALNNSLINGEKFSDFITNQIATIGENLVVRRFNTINANGGVLNGYLHSNSRVGVIISATCENVDRKKAADFIYQLCMHAAAMKPSVISYKEFNPDFLKSELTALKAELEKENEELKRLGKPLNHIPEFASRAQISDEIIEKEKEKIRAELKKEGKPEKIWDKIIPGKLERFLADNTLLDQRLTLLGQFFVMDDKKTIEQVIDEKSKEFGGKITITNYIRYEVGEGLEKKSEDFAAEVAAQIG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCN2_ARATH
Sequence: MGRSSSKKKKKRGGSGRRGQLKDHGSNADEDNELLSEEITALSAIFQEDCKVVSDSRSPPQIAIKLRPYSKDMGYEDTDISAMLIVRCLPGYPYKCPKLQITPEQGLTTADAEKLLSLLEDQANSNAREGRVMIFNLVEAAQEFLSEIIPESHDEESVPCLTAHRSTQFIEQPMLSNIAKSCSGGPFVYGFIDLFSGLEDARNWSLTPDENRGIVSSVQSHPLDTSRILHQKPDKNLKRFEDHAKEEVALPAPIAKLNTVQEENVDDTSISSFDSSKSTDDVESGLFQNEKKESNLQDDTAEDDSTNSESESLGSWSSDSLAQDQVPQISKKDLLMVHLLRVACTSRGPLADALPQITDELHELGILSEEVLDLASKSSPDFNRTFEHAFNQNMASTSVPQFWEPPSDSCEPNASLPSSRYLNDFEELKPLGQGGFGHVVLCKNKLDGRQYAVKKIRLKDKEIPVNSRIVREVATLSRLQHQHVVRYYQAWFETGVVDPFAGANWGSKTAGSSMFSYSGAVSTEIPEQDNNLESTYLYIQMEYCPRTLRQVFESYNHFDKDFAWHLIRQIVEGLAHIHGQGIIHRDFTPNNIFFDARNDIKIGDFGLAKFLKLEQLDQDGGFSTDVAGSGVDSTGQAGTYFYTAPEIEQDWPKIDEKADMYSLGVVFFELWHPFGTAMERHVILTNLKLKGELPLKWVNEFPEQASLLRRLMSPSPSDRPSATELLKHAFPPRMESELLDNILRIMQTSEDSSVYDRVVSVIFDEEVLEMKSHQSSRSRLCADDSYIQYTEINTELRDYVVEITKEVFRQHCAKHLEVIPMRLLSDCPQFSRKTVKLLTNGGDMLELCYELRLPFVHWISVNQKSSFKRYEISHVYRRAIGHSPPNPCLQADFDIVGGTLSLTEAEVLKVIVDITTHIFHRGSCDIHLNHGDLLDAIWSWAGIKAEHRRKVAELLSMMGSLRPQSSERKLKWVFIRRQLLQELKLPEAVVNRLQTVASRFCGDADQALPRLRGALRADRPTRKALDELSNLLTYLRVWRIEEHVHIDVLMPPTESYHRNLFFQVFLTKENSSGTSNDGVLLAVGGRYDWLVQEVCDREHKMNLPGAVGVSLALETIFQHLPMDLRPIRNEVSTSVLVCSRGGGGLLVQRMELVAELWEKSIKAEFVPTPDPSLTEQYEYANEHEIKCLVIITESGVAQNQIEFVKVRHLELKKEKVVGREELVKFLLDAMAVQFRNPSVWS
What is the function of this protein?
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 eIF-2-alpha in response to low amino acid availability.  Plays a role as an activator of the general amino acid control pathway required for adapatation to amino acid starvation.  Converts phosphorylated eIF-2-alpha either to a competitive inhibitor of translation initiation, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a translational initiation activation of specific mRNAs, and hence allowing reprogramming of amino acid biosynthetic gene expression to alleviate nutrient depletion.  Binds uncharged tRNAs.
What are the official names of this protein?
eIF-2-alpha kinase GCN2, serine/threonine-protein kinase GCN2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPD_DICDI
Sequence: MSTPLRGSSPQVSFYESELDQEGGSDASHFTYRNYMEDDKINSFTFNMARKDQTQLFQRIILTNESESEIEEYAEVAEQLLDAINLREKYVFHPKIWKADAPVGEKPPYSPFESDESTNCATEHMFKEVNGVYFVYSNETDMKSNKALFSVPHTLASYYKDINNLMMLSSYGPAKTFTFKRLQLLESKFNMHTLLNDSLELFQQKTAPHRDFYNVRKVDTHVHHSSSMNQKHLLKFIKRKLKENPNEIVIFRDDKYLTLAEVFKSLNLDVDELSVDTLDVHADNNTFHRFDKFNLKYNPCGQSRLREIFLKTDNLIKGKYLAEISKEVFTDLESSKYQCAEYRLSIYGRKMSEWDTLASWIVDNDLFSTKVRWLIQVPRLYDVYRETSTTTFQDFLNNVFHPLFEVTKDPSSHPKLHLFLQQVVGIDCVDDESKFEKKFTEKFPVPGEWSSEHNPPYTYYLYYLYANLYTLNQFREEKGLNILTLRPHSGEAGEVDHMGAAFYLAHGINHGINLRKTPVLQYLYYLTQIGIAMSPLSNNSLFLTYNRNPFPAFFARGLNVSISTDDPLQFHYTKEPLMEEYSIATQVWRLSVCDICEIARNSVLQSGFEHNVKSHWLGPDYANSGGNDIKKTNISDIRVCFRNETLIEELHLILKSLQTLPNFKNLNINFLLDKLPSEITTGNDYKLKKAQLKLNGANKLRNSSVGSTPNNGTPSSSGTPSLSSPGAIVHLMKTKPYIPPPLSLNIKQENNNNNNNNNNNNNNNNNNNTNTNTNSNSTTTNQDDNSKSDK
What is the function of this protein?
Catalyzes the conversion of adenosine monophosphate (AMP) to inosine monophosphate (IMP) and ammonia (NH4(+)) (PubMed:11784104, PubMed:1916064).  Participates in the regulation of the adenylated nucleotide pool and the interconversion to guanylated nucleotides during early morphodifferentiation (PubMed:1916064, PubMed:17259634).
What are the official names of this protein?
AMP deaminase, AMPD1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_METKA
Sequence: MTITEEDLIEPLRKVVEYSPPRRFLETVDMIVNVKGVDLSDPSQRIDKEVVLPHGRGKPVNVCVIAEGEMAREAEEAGATVINREKLEELAENVREAKKIARRHEFFYAQVDLMPDVGRVLGPVLGPRGKMAKPVPPNADIRALIERAHRTARVRMRDQPVIHTVIGARNMEPEQLAENAMAVLREITSELEKSWAQIDSVYVKTTMGPAERVY
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LIGB_SALPK
Sequence: MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEITRLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWVRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKAAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTKKYSLAVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQYWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPGSHFNSLTCFYASATCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFEHIFSWLALTSAQIANTPGVAKGKSEQIWRQFYLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWRQLPATGERRAGRVIDWRNNPQINALSRWLAAQHIPGFGS
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: TRUA_ECOLU
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL23_LACP7
Sequence: MANLKYYDVILKPIVTEKSMNSMSEKKYSFSVHPEATKTQVKEAVEKMFAGTKVASVNTMNLEGKNRRRGNTSGKTSKTKKAIVQLTADSAEIEIFTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y4120_BACHK
Sequence: MDGFDKTMKFSIQDEKQSVHVNDVLLTVYDALQEKGYNPINQIVGYLLSGDPAYIPRHKDARSIIRKLERDELIEELVKSYLKHHREE
What are the official names of this protein?
UPF0297 protein BT9727_4120.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: MNTR_BACC4
Sequence: MPTPSMEDYIEQIYLLIDEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLIYEKYRGLVLTTKGKKIGERLVYRHDLLEQFMRIIGVDESKIYNDVEGIEHHLSWEAIDRIGDLVQYFEQDAVRVETLRGVQRANEEKSN
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_COXBU
Sequence: MKPIAIYPGTFDPLTNGHVDIIERALPLFNKIIVACAPTSRKDPHLKLEERVNLIADVLTDERVEVLPLTGLLVDFAKTHQANFILRGLRAVSDFDYEFQLAHMNYQLSPEIETIFLPAREGYSYVSGTMVREIVTLGGDVSPFVPPLVARHLQKRREK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ECO8A
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: LECB_SPAPA
Sequence: AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDSNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVGDTTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASKGYIETHDVFSWSFASKLAG
What is the function of this protein?
Galactose-binding lectin.  Agglutinates human erythrocytes, and requires Ca(2+) and Mn(2+) ions for full agglutinating activity.  Has antifungal activity against Fusarium sp. , A. niger and A. flavus.
What are the official names of this protein?
Seed lectin beta chain.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: LPXB_SHIDS
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEIEELAVMGIVEVLGRLRRLLHIHADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDTHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKLLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: GEOA_CASDE
Sequence: MNDTQDFISAQAAVLRQVGGPLAVEPVRISMPKGDEVLIRIAGVGVCHTDLVCRDGFPVPLPIVLGHEGSGTVEAVGEQVRTLKPGDRVVLSFNSCGHCGNCHDGHPSNCLQMLPLNFGGAQRVDGGQVLDGAGHPVQSMFFGQSSFGTHAVAREINAVKVGDDLPLELLGPLGCGIQTGAGAAINSLGIGPGQSLAIFGGGGVGLSALLGARAVGADRVVVIEPNAARRALALELGASHALDPHAEGDLVAAIKAATGGGATHSLDTTGLPPVIGSAIACTLPGGTVGMVGLPAPDAPVPATLLDLLSKSVTLRPITEGDADPQRFIPRMLDFHRAGKFPFDRLITRYRFDQINEALHATEKGEAIKPVLVF
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of geraniol to geranial.  Is involved in the anaerobic degradation of the monoterpene beta-myrcene.  Can also catalyze the oxidation of (S)-perillyl alcohol to perillyl aldehyde, and to a lesser extent, the oxidation of nerol, citronellol, cumic alcohol, and benzyl alcohol.  Cannot use NADP(+) instead of NAD(+) as cosubstrate.
What are the official names of this protein?
Geraniol dehydrogenase, GeDH, Geraniol oxidation pathway protein A, Perillyl-alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: SP5G_STAAR
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDEIDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: RHAA_ECOBW
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKEILSRRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPFB1_XENBO
Sequence: GFKQFVHSMGKFGKAFVGEIINPK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Xenoposin-precursor fragment B1, XPF-B1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPZ_ECOK1
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPVLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: ECPR_ECOKI
Sequence: MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon.  Also represses expression of the flagellar master operon flhDC, and consequently prevents flagellum biosynthesis and motility.  Acts by binding to the regulatory region of the flhDC operon.
What are the official names of this protein?
HTH-type transcriptional regulator EcpR, Meningitis associated and temperature regulated protein A.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.