PharMolix/UniProtQA huggingface dataset:
Protein: SECA_DECAR
Sequence: MISGLLKKIFGSRNDRLIKQYSQNVKRINALEPAMQALSDEQLRAKTDEFRQRHANGESLDDLLPEAFAVVREAGQRALGMRHFDVQMIGGMVLHDGKIAEMRTGEGKTLVGTLPAYLNAISGKGVHVITVNDYLATRDSDWMGRLHRFLGLTVGVNLSQMDHEAKQAAYAADITYGTNNEFGFDYLRDNMVYTAGERVQRSLNFAIVDEVDSILIDEARTPLIISGQAEDHTDLYLRMKDVVPNLTRAMEEKDEGDYWVDEKGHQVHLSETGYEHAEQLLAEYGLLKEGTSLYDAANITLMHHLNAALRGMTLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEGVQIQAENQTLASITFQNYFRMYNKLAGMTGTADTEAYEFHQIYGLETVVIPTHRPMVRKDMNDLVYKTADEKHAAIIADIKDCAKRGQPVLVGTTSIEASELLSGLLDKESLPHQVLNAKQHAREAEIVVQAGRPGMVTIATNMAGRGTDIVLGGNIEKQLAAIRDDESLPVEEREQKAAAMKAEWQEVHNAVLASGGLHIIGSERHESRRIDNQLRGRAGRQGDAGSSRFYLSLDDPLLRIFAGERLRAIMDKLKMPEGEAIEHPLVTRSLESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLETDDISETITAMRQSVIAETFRTYVPAESVEEQWDMEGLERALASDLQIIAPVAQWFKDEPTLSDEEILERITKNADEAYQAKIDLVGDGTFHQFERNVMLQSLDSHWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFEGLLDLVRREVTRVVFTVQIRTPEDVEETAPHAEVQNVQYQHAGYDEALGEGEGAEAAGQQPADAGPKIGRNDPCPCGSGKKYKHCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: UFSP2_MOUSE
Sequence: MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLSDLTTKLSSDALVLRVCNSSVYLWPNSDANTGELTDSSACKNVVRFIQFDQEEDTKRKFIKKKDKKLTDTQQIVNIDLMLEISTPLGAVTPILERENEEHHYINMSLPIDAVVSVAPEESWGKVRKLLVDAILRQLVDVEKCILRYMKGTSIVVPEPLHFQLPGKKNLVTVLYPSGIPDDQLQAYRKELHDLFNLPHDRPYFKRINAYHFPDELYKDGYIRNPHTYLSPPNIEGSMICVVQGTYAYHHYMQDRIDDNGWGCAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQMVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMVGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVMLEKGWCGWKSPDFWNKDAYYNLCLPQRPNAL
What is the function of this protein?
Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins.  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins (PubMed:17182609, PubMed:21228277).  Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation (By similarity).
What are the official names of this protein?
Ufm1-specific protease 2, UfSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus.
Protein: CYB_MARMN
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISTWWNFGSLLGLCLVIQIFTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGMYYGSYTYFETWNIGVILLFMVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFITTALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGALLLILILMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHLSKQRSMMFRPLSQCMFWILVADLITLTWIGGQPVEYPYIIIGQLASILYFAIILLILPTISLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1147_FUSNN
Sequence: METKIEKVLKILEEEIVAAEGCTEPIALSYAAAKARRILGTVPNKVDVFLSGNIIKNVKSVTIPNSEGMIGIEPAIAMGLIAGDDKKELMVISDTTHEQVQEVRDFLDKKLIKTHVYPGDIKLYIRLEISNGENNVLLEIKHTHTNITRILKNDKVLLSQICNDGDFNSSLTDRKVLSVKYIYDLAKTIDIDLIKPIFQKVIRYNSAIADEGLKGKYGVNIGKMILDNIEKGIYGNDVRNKAASYASAGSDARMSGCALPVMTTSGSGNQGMTASLPVIKFAAEKNLSEEELIRGLFVSHLITIHVKTNVGRLSAYCGAICAASGVAAALTFLHGGSFEMVCDAITNILGNLSGVICDGAKASCAMKISSGIYSAFDATMLALNKDVLKSGDGIVGVDIEETIRNVGELAQCGMKGTDETILGIMTK
What are the official names of this protein?
UPF0597 protein FN1147.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: RER1D_ARATH
Sequence: MEDEPGSENEADTIVASPLAKWRIEFSKSFQNYLDRSAPNIVRRWLVTLVAAVIYIYRVYSVYGYFVISYGLATYILNLLIGFLSPKVDPELEALDPDSLPVDESDEYKPFVRRLPEFKFWYAATKAFVVAFVMTFFSFLDVPVFWPILLCYWLVLYSLTMKRLIVHMFKYRYFPFDVRKPVKLLKFLVNSVLTFLRLKKGDGGDDRPSSSNSSQGNEKQD
What is the function of this protein?
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
What are the official names of this protein?
Protein RER1D, AtRER1D.
What is the protein family that this protein belongs to?
Belongs to the RER1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRCT1_HUMAN
Sequence: MSSQQSAVSAKGFSKGSSQGPAPCPAPAPTPAPASSSSCCGSGRGCCGDSGCCGSSSTSCCCFPRRRRRQRSSGCCCCGGGSQRSQRSNNRSSGCCSGC
What are the official names of this protein?
Cysteine-rich C-terminal protein 1, Protein NICE-1.
Protein: UVRC_PARXL
Sequence: MTEPEATDVFEPKKVLTQLPHLPGVYRYYDTHGAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMVTRIARVETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHKFPRMAYYRGAVDRKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCTAPCVAAISEEDYARDVANASRFLLGRQGEVMSELEQKMHAFASELKFEQAAAVRNQMSSLSTVLHQQAIEVGSDSDVDILAVVALGGRVCVNLAMVRGGRHLGDKAYFPAHVESALTVDEGGLEDGDERLADAATGPVSLAEEEVGGEAEPADTADALAIARDMPPEDEQDEDEDEDEQDGEPEEAGSGADSDSDSAKPRKGRATGGIESEVLEAFIAQHYLGNRVPPVLVVSHAPATRELVDVLIEQAGHKVTVLRQPQGQRRAWLVMAEQNARLALARLLSEQGSQQARTRALTDTLGMECDDLAHLRIECFDISHTMGEATQASCVVYHHHKMQSSEYRRYNITGITPGDDYAAMRQVLTRRYEKMVAQAAANAADEAAELQSDAAADPSLAPDAAEPVAAGGVLPTIVLIDGGKGQVEIARQVFTELGLDTGMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRGKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVEDLASVEGISQALAEQIYRQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_STAA3
Sequence: MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHYFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRSENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSWI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LSR2_MYCBO
Sequence: MAKKVTVTLVDDFDGSGAADETVEFGLDGVTYEIDLSTKNATKLRGDLKQWVAAGRRVGGRRRGRSGSGRGRGAIDREQSAAIREWARRNGHNVSTRGRIPADVIDAYHAAT
What is the function of this protein?
DNA-bridging protein that has both architectural and regulatory roles.  Influences the organization of chromatin and gene expression by binding non-specifically to DNA, with a preference for AT-rich sequences, and bridging distant DNA segments.  Represses expression of multiple genes involved in a broad range of cellular processes.  May coordinate global gene regulation and virulence as well as genes important for adaptation to changing O(2) levels.  Protects against reactive oxygen intermediates (By similarity).
What are the official names of this protein?
Nucleoid-associated protein Lsr2.
What is the protein family that this protein belongs to?
Belongs to the Lsr2 family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y1793_STAAC
Sequence: MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFDKDK
What are the official names of this protein?
UPF0354 protein SACOL1793.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: URE2_TOLAT
Sequence: MIPGEIQVADGDLLLNEGRATLQVAVANTGDRPIQIGSHYHFFETNPALQFDRAATRGFRLDIPAGTAVRFEPGQTRTVTLVAYAGRRHVYGFRGDVMGPLDEIAQSDQGAQHEQGAQA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP1_METJA
Sequence: MTYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINPETRLPRNYFRFLGVMEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKLTHPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of pseudouridine at position 914 (Psi914) in 16S rRNA.  Is not able to methylate uridine at this position.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1, 16S rRNA Psi914 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: RS20_BRUME
Sequence: MANTPSAKKAVRKIAARTEINKSRRSRVRTFVRKLEDALLSGDKQAAEVAFKAVEPELMRAASKGVVHKNTAARKVSRLAKRVKALNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NADK_SALPA
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O5AC1_HUMAN
Sequence: MAEENKILVTHFVLTGLTDHPGLQAPLFLVFLVIYLITLVGNLGLMALIWKDPHLHTPIYLFLGSLAFADACTSSSVTSKMLINFLSKNHMLSMAKCATQFYFFGSNATTECFLLVVMAYDRYVAICNPLLYPVVMSNSLCTQFIGISYFIGFLHSAIHVGLLFRLTFCRSNIIHYFYCEILQLFKISCTNPTVNILLIFIFSAFIQVFTFMTLIVSYSYILSAILKKKSEKGRSKAFSTCSAHLLSVSLFYGTLFFMYVSSRSGSAADQAKMYSLFYTIIIPLLNPFIYSLRNKEVIDALRRIMKK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5AC1, Olfactory receptor OR3-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAT_HV1Z3
Sequence: PSSQPRGDPTGQEEPKKKVEKKTTTDPFD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Tat seems to inhibit the HAT activity of KAT5/Tip60 and TAF1, and consequently modify the expression of specific cellular genes.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines (such as IL10) or cytokine receptors.  May be involved in the derepression of host interleukin IL2 expression.  Mediates the activation of cyclin-dependent kinases and dysregulation of microtubule network.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Host extracellular matrix metalloproteinase MMP1 cleaves Tat and decreases Tat's mediated neurotoxicity.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.  Binds to KDR/VEGFR-2.  All these Tat-mediated effects enhance angiogenesis in Kaposi's sarcoma lesions (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type (By similarity).
Protein: PETG_RHDSA
Sequence: MIEPLLFGIVLGLIPVTLVGLFVAAYLQYRRGNQFGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: M3H15_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILSGLKTALKGAAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVGNALGGLLKNLG
What is the function of this protein?
Maximin-H15 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 3/H15.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YICS_ECOL6
Sequence: MKPTMLLMITVFLIFPAISQAESPFSSLQSAKEKTTVLQDLRKICTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM
What are the official names of this protein?
Uncharacterized protein YicS.
Protein: Y1880_SYNY3
Sequence: MISSAATFRQHQEILVIATQGKSLHNFNSKIQAVVQHSGVKTGLCTVFVRHTSASLIIQENADPDVLTDLAIFFAQLVPEDGRRYRHSTEGLDDMPAHIRSALTKTSEHIPIVNGRLGLGTWQGVFLWEHRQRPHQREVIVHVSGEV
What are the official names of this protein?
UPF0047 protein sll1880.
What is the protein family that this protein belongs to?
Belongs to the UPF0047 family.
Protein: RL35_METC4
Sequence: MPKLKTKSGAKKRFKITGTGKVMYAQAGKRHGMIKRTNKQIRNLRGTTTLFEGDAANVKKYFLPNQR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ENGB_LIGS1
Sequence: MQVHNVNLTISAVRPEQYPDAKLPEVALAGRSNVGKSSLINTLINRRNYARTSSQPGKTQTLNFYNIEDLLYFVDVPGYGYAKVSQKEREKWARMIETYFSTRQELKGAISLVDARHEPSELDCQMIEFLHYYNIPVLVVGTKIDKIPKSKRNKSESQIRKKLQLTKNDRLILFSAVDKIGKDEVWNWIESITKVN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL41_ASHGO
Sequence: MRAKWRKKRVRRLKRKRRKVRARSK
What are the official names of this protein?
60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
Protein: T132E_HUMAN
Sequence: MAPGMSGRGGAALLCLSALLAHASGRSHPASPSPPGPQASPVLPVSYRLSHTRLAFFLREARPPSPAVANSSLQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPSSTLDIPERLTVNWKVRAFIVRSHVPASQPVVQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPAPAAPPTARRKSPDGLEPEATGESQQAELYYTLHAPDASGGCGGSRRGAGPGVGARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSILLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVAWAQSTPLPPREGQGPLEILQLDFEMENFTSQSVKRRIMWHIDYRGHGALPDLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVNGLVLDISALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVPILPDRRSVRESEDEDEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHMVDSSTLAGLEPGTTPFKVVSPLTEAVLGETLLTVTEEKVSITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDEHVATVTQDRAFPLVVAEAEGSGELLRAELTIAESCQKTKRKSVLATTPVGLRVHFGRDEEDPTYDYPGPSQPGPGGGEDEARGAGPPGSALPAPEAPGPGTASPVVPPTEDFLPLPTGFLQVPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPPEGQTSMDHSHHWVFLGNGQPLRVQGELSPPAGNPLETVPAFCHGDHHSSGSSQTSVQSQVHGRGDGSSGGSARDQAEDPASSPTSKRKRVKFTTFTTLPSEELAYDSVPAGEEDEEEEEDLGWGCPDVAGPTRPTAPPDLHNYMRRIKEIA
What is the function of this protein?
Required for normal inner ear hair cell function and hearing.
What are the official names of this protein?
Transmembrane protein 132E.
What is the protein family that this protein belongs to?
Belongs to the TMEM132 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SUB2C_COCP7
Sequence: MQLLNLSLFFLLPFATANPIPQDSQNIIPGQYIVTLKDGLTTAEIDAHKTWLAFTHRSNIAAKGHSGIESEGVFKHFQIHKLNMYAAGLDKKTVEELRRSPHVKSVLPDQKIYLAEAVTQSNAGWNLGYMSSKGQPSPSWSTLTNYTYDSTAGEGVWAYVLDTGVNVNHVEFEGRAILGRNSIPNRPHEDTFGHGTYVGGIIAGKTYGVAKKATVVSAKAFDGGSSSYRYILDSYEWIVKNITDSDRKSKSVINLSISGAKYQPFDEAIENAFQAGITTVVASGNDGRDASQNTPASSPNAITVGALRWENTRPGFSNYGKVVDLFAPGELIRSGWTGGNNATRVASGTSAASPHVAGLVAYLMSIETLSSPSEVTARVLNLTIPGLVKDARGSPNKVAYNGIQEML
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease CPC735_013710.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_CUPTR
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRGGRAVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS11_FLAJ1
Sequence: MAKATAKKRKVIVESTGEAHISSTFNNIIISLTNKKGEVIAWSSAGKMGFRGSKKNTPYAAQMAAEDCSKVALEAGLKKVKVYVKGPGNGRESAIRSIHNGGIEVTEIIDVTPMPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: COF1_MOUSE
Sequence: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPENAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
What is the function of this protein?
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:11809832).  In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:25208553).  Required for the centralization of the mitotic spindle and symmetric division of zygotes (PubMed:25208553).  Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity).  Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity).  Required for neural tube morphogenesis and neural crest cell migration (PubMed:15649475).
What are the official names of this protein?
Cofilin-1, Cofilin, non-muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, growth cone. Cell projection, axon. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.