PharMolix/UniProtQA huggingface dataset:
Protein: KIFC1_HUMAN
Sequence: MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATTKITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTSGVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRLHNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK
What is the function of this protein?
Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429).  May contribute to movement of early endocytic vesicles (By similarity).  Regulates cilium formation and structure (By similarity).
What are the official names of this protein?
Kinesin-like protein KIFC1, Kinesin-like protein 2, Kinesin-related protein HSET.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Early endosome. Note=Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis.
Protein: DYR_STAAR
Sequence: MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: RL4_SULIY
Sequence: MYLELVKKNSVILDKDGNKVKEVELPFIFSFPVRKDIIRRVFLAEFTHSLQPKGRDPMAGKRTSAESFGINLGMARVPRVKNSGEAALAPNTVGGRLTFPPSVDKKLVEEVNDKEKQLAVISALSATADKVFVKARGHVFKDSVSFPIVVTDDIVSLKTASEVEEFLEKIGVYDDVKRVKERIRIRAGKGKMRGRKYKESIGPLIIVHDSNSPIVKAARNIAGVDVVNAKDVSVIHLAPGAHSGRLTIYTETSIKILDERLSKRLVS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SSRP_DICNV
Sequence: MSKKNTADNHIVTNKKVFHDYFLEEHFEAGIALEGWEVKAVRAGRIQIKESYILVKDQQVYLFGALIHPLASASSHIFPEAQRTRKLLLHRYQIAKLIGASERDGYTLMPVSLYWKNGFVKVDVAIAKGKKEFDKRQVKKDQDWKKTQSRIMKAHKRQL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DCMM_AFIC5
Sequence: MIPGSFDYHRPKSIADAVALLTKLGEDARPLAGGHSLIPIMKTRLATPEHLVDLRDIGDLVGIREEGTDVVIGAMTTQHALIGSDFLAAKLPIIRETSLLIADPQIRYMGTIGGNAANGDPGNDMPALMQCLGAAYELTGPEGARIVAARDYYQGAYFTAIEPGELLTAIRIPVPPTGHGYAYEKLKRKIGDYATAAAAVVLTMSGGKCVTASIGLTNVANTPLWAEEAGKVLVGTALDKPALDKAVALAEAITAPASDGRGPAEYRTKMAGVMLRRAVERAKARAKN
What is the function of this protein?
Catalyzes the oxidation of carbon monoxide to carbon dioxide.
What are the official names of this protein?
Carbon monoxide dehydrogenase medium chain, CO dehydrogenase subunit M, CO-DH M.
Protein: NUOD_RHIWR
Sequence: MASTYDTLTPEAQKGEVEIQNYTINFGPQHPAAHGVLRMVMELDGEIVERVDPHVGLLHRGTEKLIEYKTYLQALPYFDRLDYCSPLGMEHSYVLAIEKLLQLEVPLRAQYLRVLFAELTRICNHMLNIGSHVMDVGAMTPNLWLFEIREDCLNFFERASGARMHAAWFRPGGVHQDVPLKLLTDIGDWLDTRLPRLFEDAVSLFADNRIFKQRNVDVGVVSKEDALAWGFSGPMIRAAGIPWDIRKSQPYDVYDRMDFEIPVGTKGDCYDRVMVRIEEVRQSARIMKQCLSEMPEGPIASLDRKVVPPKRGEMKRSMEALIHHFKLYTEGFHVPAGDVYVATESPKGEFGVYLVSDGSNKPYRCKIRPTAFSHLQAMDFMMKGHMLADTTAILSAIDVVFGECDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GAR5A_HUMAN
Sequence: MGPPLWPDLQEPPPPGTSSQIRSPLLCDVIKPAPHHDVTVRVVPPPRFLPLLLRPLPSDGDIAMRRDRGPKPALGGAGEVEPGGMAASPTGRPRRLQRYLQSGEFDQFRDFPIFESNFVQFCPDIYPAPTSDLWPQVTRLGEVANEVTMGVAASSPALELPDLLLLAGPAKENGHLQLFGLFPLKFVQLFVHDKSRCQLEVKLNTSRTFYLQLRAPLKTRDREFGQWVRLLYRLRFLSASAVPFTQE
What is the function of this protein?
RAB2B effector protein which promotes cytosolic DNA-induced innate immune responses.  Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 5A.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: HIS7_ACTPJ
Sequence: MTQPTLFIDRDGTLIDEPKTDFQIDSLEKLKLERNVIPALLKLKDHYRFVMVSNQDGLGTDSFPQENFDKPHNAMLEIFRSQGIEFDAILICPHKPEDNCDCRKPKIKLLKKYIDKKLFDPAHSFVIGDRATDVQLAENLGIQALQYHPEKLDWDLIVEKLLPKTTACKRPPRYAEVVRTTKETDIKVQVWLDETGVNQISTGVGFFDHMLDQIATHGGFRMNVQCKGDLWIDEHHTVEDTALALGTALKQALGDKRGIQRFGFVLPMDECKAECTMDLSGRPYFKFKAKFKREKVGDFSTEMTEHFFQSIAYTLMATLHLKTQGDNDHHKIESLFKVFGRTLRQCIKVEGNELPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDA9_YEAST
Sequence: MSSEEFKGLPIKRDISSTIYADRPPALSAPPCVGATGNDKIQVLPIPKKSRTIKTDKPRPFLCHICTRGFVRQEHLKRHQRAHTNEKPFLCVFCGRCFARRDLVLRHQHKLHSALVSKESINSKDKTEIDAINDKNIIQIQGNKQTILPTPSNPLAKTAVQLKKAAKEKKNGKQGKLDLSPSYGANNHSTDVSPSVGNSSTPAVIEETDSSSHFPLPDTNIPTKSKRHASFSASSAFTYSSDNFQKLHQQAKSDFDELQESIPHQVGFSTPQLTAQQLIENAIESGVVDLETLDLPPFLSLDGLPPASSSAAVAASEQIDICPSSATDTISGANSTPNQAATAPPFQLPIARESSSLFLANTPYLSDFLTMGSSYGGSGGFAKSITADPSLDYFNYKNHSHPDSRHNNSSSGINYSNNKNNNESIEKSQNNSNVINETIDHTDIHAHHADAHDDSFIESEEWLSKFIMDSQIDNDLKLNINHFNDIGFNNLHPQNPTTHSEPRNMHNENRDMHRSASKFQSVSENISPREQMSLFKTKQNKAISKFLSDEKIPSTASPSSSASPVQFDKKNVDINEFLLDESVSNLFTTRQIDLFKKNVNLYSPLFQNQKDAVSSTSLTPSLTTQTATTQSGPGWTDSSQKLTFFTEQLRNLIIKENNLKSNLFPTVDELNHYVDLYQVEFHKYFPFIHLYSIIPSSENYPLVISISMIGALYGFHSTHALLLSKIARTRVRMFLENTRSNHDKTPIWLMQSLVLLTFTSIFSNDMNAFRTVNTQIMILVQLIKISKLNYPLENFIKPPIESDHVLEYQDNPAVLNQFKAQYNTREQINRNFKYFILAQSRIRICHIVLLISNLFKSLVDFDCCFHSIDLKCGVPCYNEVLFFCENSRTWNENLTRFNIVLDSKFSLIEVSNGESNYEKCLMYLSNGNPYLYKNAKISFKTLLSLLISIHEKINIERDALKDSYESDFHAKNVQWRMHSRPLVATMLKHWELLYIKNGGILALSDENLPIINTNPSFRLIIPLYFFAKLRKCLDIAPTLRCIWNQDWNSMNSSLEKVCYERESLREATEYAVSVITFWIDTVSVMKGKSTQTPIFTITCIFVSILVIAGYMRRLEDFAQNKNSDCMIGSLKSTDRILWLKAFKTLKRIESHLSEREYKLQTFAEFLRVPDNGSLDIESLDSSLIENTLNSHDVTNQALDIITRTRLSSRTLYCGARILGDTPVWPVSLLFAHALQSRAIYNINHRKSVNSV
What is the function of this protein?
DNA-binding protein that acts probably as a transcription factor.
What are the official names of this protein?
Probable transcription factor TDA9, Topoisomerase I damage affected protein 9.
What is the protein family that this protein belongs to?
Belongs to the RSF2/TDA9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3663_CAUVC
Sequence: MNDFNRGYARSIPADRADMSVDAGLRKFMLGVYNKVALGLVVSGALAYATSSVPAVRDLLFVVQGGRLAGVTPLYMVVAFAPLVLMLIAGFAMRNPKPETAGALYWTIVSLIGASLGSVMLRYTGESVAATFFVTATAFGGLSLFGYTTKKDLTGFGSFLMMGVIGLIVASIVSIFLKSPALLFAINVLGVLIFSGLIAYDTQRLKMTYYEMGGDRASMAVATNFGALSLYINFINLFQFLLSFFGGNRE
What are the official names of this protein?
Uncharacterized protein CC_3663.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TTYH3_XENLA
Sequence: MAAAISYTPPWWVNLLHRLPHLNLQWESLNGDFRPEDPDYQQSLMLLACVALSCLALDLLFLLFYSFWFCCRHRKTEENTNADCCCTVWCVIVATLVCSAGIAVGFYGNGETSDGIHRVTYSIRHVNRTMAGIHDRVSDTTTSLNQTVEPCLQNLEVMFTKQTDYLRIVQRLQSLLYTLVQQTSEIPFWKNHYLLDEFAAQVDLFDWYRWLGYLGLLLFHVFICLLVLFGLIRNSKGTLICVCFLGMMALIISWASMGLELAVAVGSSDFCVNPDTFVSKMVEEKSVLRADILNYYLVCNTGSPNPFQQMLSSGHKALVEMQDDVRDLLRSAVKEYPNSKDYLVCIQGVLNSTEINLQHLTALVDCRGLHLDYVQSLTGFCYDGVEGLIYLVLFSFVTALMFSSIVCSVPHTWQQRRANYEEGDEETTTPGTRQTHDNLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATNRPETDPVH
What is the function of this protein?
Probable large-conductance Ca(2+)-activated chloride channel.
What are the official names of this protein?
Protein tweety homolog 3.
What is the protein family that this protein belongs to?
Belongs to the tweety family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_BORBR
Sequence: MAEITAALVKELREKTDAPMMECKKALTEAEGDLARAEEILRVKLGNKASKAAARVTAEGLIGLYIAADGKQGAVIEVNCETDFVAKNTDFIDFINKLAELVATQNPADVAALSALPFGEGTVETTRTALVGKIGENISVRRFERIQTPNSLASYVHGGKIGVLVEFSGAEEVGKDLAMHIAATKPKALNADGVNAEDIAAERSVAEQKAAESGKPAEIVAKMVEGSVQKFLKEVTLLSQPFVKNDKQTIEQMLKEKGASITKFVLFVVGEGIEKKTADFASEVAAAAAGRA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJDN_ECOLI
Sequence: MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSAQDSAENCPSGMQFPDTAIAHANVRIAGSDIMMSDAMPSGKASYSGFTLVLDSQQVEEGKRWFDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ
What are the official names of this protein?
Protein YjdN.
Protein: HSLU_STAHJ
Sequence: MDANGIKLTPKDIVSKLDEYIVGQDDAKRKVAIALRNRYRRSLLDEETKQEIAPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVAVRLVKDQKKGLVKDEAVNKANEKLVKLLVPSMKKKASNNSNPLESLLGGAIPNFGNNDDEEEETPTEEIKTKRSEIKKQLLDGKLEEEKVRIKVEQDPGALGMLGTNQNQQMQDMMNQLMPKRKVEREVPVKTARKILADDFADELIDQETANQEALELAEQMGIIFIDEIDKVATNNANSGQDVSRQGVQRDILPILEGSMIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELESLTVDDFYRILTEPKLSLIKQYEALLQTEEVTVNFTKEAITRLAEMAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAP9_ADE41
Sequence: MSGSMEGNAVSFKGGVFSPYLTTRLPAWAGVRQNVMGSNVDGRPVAPANSATLTYATVGSSVDTAAAAAASAAASTARGMAADFGLYNQLAASRSLREEDALSVVLTRMEELSQQLQDLFAKVALLNPPANAS
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: YFE6_SCHPO
Sequence: MWNPKKKSEALAKFKSFPYPKPGTSNVLDSKEGDTRRKYFTKTHLHRLFVFVVLLLCSGYFLKHTLLTRPKESNVVMIFVNNIGGGVLDVKSPRQWELEKISTENKKKYAERHGYHFFVKSTGLKRRYAHEWRESWEKADYIMEAMKKYPHAEWFWWVDLTTFIMEPQYSLEKLIINRLDHIATRNITDSMEFNPKNFHEIPFVDYSEDINFILGQDCNGFSLGSFLVRRSDWTSRLMDFLWDPVVYGQKHMDWPHDEQNAIEYFYENNAWLRSGMGFVPLRLFNSYPPGACAGEGENPRFFYNQKEGDFLVNLAGCNYGRDCLDEINHYKGLAQRKRGWRKLVPFL
What are the official names of this protein?
Uncharacterized alpha-1,2-galactosyltransferase C637.06.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: YCF26_PORPU
Sequence: MFSFRNQQVLTFVSSLSTFVTIILNHLKKWWSDVTLRTRLMAMTTLMVSLLMSSLTFWTLTSIQQETRLIDNRFGKDLSLLLAVNITPILEGDNYLQLQQFIEHFYLSTSSIRYILVFNADGQIYYSIPFSSETAINFFSLSEYNCFRNENHYFSNTPIVNTNNRLQGEVIDIIIPLSKEKKLLGILNIGINSNPTLTTSSQLTRDVSVAVFISIWLMVILGAAFNAFTITRPIRELLTGVKNIASGDFYQRIDLPFGGELGALIFNFNEMAERLEKYEQQNVEKLTSEKAKLETLVSTIADGAILLDKDLRVILVNRTAIENFGWEGKNIAGSIIVDYLPEDINQQLFPILNDIIRKNFLEQSICETQEICIKLQKNYKKTFRVLLTTVLDHKYSILKGIAMTIQDRTQEVELNEIKNQFISNVSHELRTPLFNIRSFLETLYEYHDSLDDSQKLEFLAIANKETGRLTRLVNDVLDLSRLESDQEYTLQPTDLVSAVEQTIRTYQLSAKDKRIDLHIDIEQNLQCVLGNYNLILQILANLVVNSLKFTHPNGIIILRAYTVDDLKTETEVQHFNSQKVRVEICDNGIGISRKNQERIFARFLRIENYVHTLEGTGLGLSIVKNIIQKHNSEIHLYSELKNGSCFFFDLMIAKDE
What are the official names of this protein?
Uncharacterized sensor-like histidine kinase ycf26.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: MYSS_CHICK
Sequence: MASPDAEMAAFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVHPKESFVKGTIQSKEGGKVTVKTEGGETLTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVLAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAASGEKKKEEQSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLPAERSYHIFYQIMSNKKPELIDMLLITTNPYDYHYVSQGEITVPSIDDQEELMATDSAIDILGFSADEKTAIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLMGLNSAELLKALCYPRVKVGNEFVTKGQTVSQVHNSVGALAKAVYEKMFLWMVIRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNISGWLEKNKDPLNETVIGLYQKSSVKTLALLFATYGGEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMANLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRVLYADFKQRYRVLNASAIPEGQFMDSKKASEKLLGSIDVDHTQYRFGHTKVFFKAGLLGLLEEMRDDKLAEIITRTQARCRGFLMRVEYRRMVERRESIFCIQYNVRSFMNVKHWPWMKLFFKIKPLLKSAESEKEMANMKEEFEKTKEELAKSEAKRKELEEKMVVLLQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAHQQTLDDLQVEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAHDSIMDLENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSRAKAEKHRADLSRELEEISERLEEAGGATAAQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSTAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMESVSKAKANLEKMCRTLEDQLSEIKTKEEQNQRMINDLNTQRARLQTETGEYSRQAEEKDALISQLSRGKQGFTQQIEELKRHLEEEIKAKNALAHALQSARHDCELLREQYEEEQEAKGELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMVDVERSNAACAALDKKQKNFDKILAEWKQKYEETQTELEASQKESRSLSTELFKMKNAYEESLDHLETLKRENKNLQQEIADLTEQIAEGGKAVHELEKVKKHVEQEKSELQASLEEAEASLEHEEGKILRLQLELNQIKSEIDRKIAEKDEEIDQLKRNHLRIVESMQSTLDAEIRSRNEALRLKKKMEGDLNEMEIQLSHANRMAAEAQKNLRNTQGTLKDTQIHLDDALRTQEDLKEQVAMVERRANLLQAEVEELRGALEQTERSRKVAEQELLDATERVQLLHTQNTSLINTKKKLETDIVQIQSEMEDTIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMDQTVKDLHVRLDEAEQLALKGGKKQLQKLEARVRELEGEVDSEQKRSAEAVKGVRKYERRVKELTYQCEEDRKNILRLQDLVDKLQMKVKSYKRQAEEAEELSNVNLSKFRKIQHELEEAEERADIAESQVNKLRVKSREIHGKKIEEEE
What is the function of this protein?
Muscle contraction.  Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
What are the official names of this protein?
Myosin heavy chain, skeletal muscle, adult.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: NCPP_VIBCM
Sequence: MPPIIKRRVMRKIIIASQNPAKVNAVRSAFSTVFPDQEWEFIGVSVPSEVADQPMSDEETKQGALNRVRNAKQRHPGAEYYVGLEAGIEENKTFAWMIVESDQQRGESRSACLMLPPLVLERLRQAKELGDVMDEVFGTENIKQKGGAIGLLTRHHLTRSTVYHQALILALIPFINPEHYPSA
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: Y2678_METMA
Sequence: MSRIKIILLACMLALLFSGCVENSAVFEKNTATLKENTINADSVRGYDIASANNAFAFDMYSQLTQQVTGDYENILFSPYSISAAMAICYEGAENTTKEQISNVFYFPTNKTVLKVRLERINDRINSGSGDYELQTANALWIQEGYPVKEEYLFNVKKYYDGEVANLDFVRKPDDSRNTINEWVETRTSDKIKDLVPKSMITPDTRIIITNAIYFNGKWAYTFDKQLTEKRAFYPANGEEASVDMMYMYNNFNYGENSKAKIIELPYKGNDLSMYIVLPKDNNIKEFETEFTINDYTELKNEMDSTVNVDILIPKFKFETKTELSDSFVEMGVVDAFRQANFSGISNSPLKVSEVIHQTFIDVKEEGTEAAAATGVGMTVGMDFSWDSKQREFKADHPFMFFIEDRRTNCILFMGKVEYPEYKNDT
What are the official names of this protein?
Uncharacterized serpin-like protein MM_2675.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: NDHJ_WHEAT
Sequence: MQQGWLSNWLVKHEVVHRSLGFDHRGIETLQIKAGDWDSIAVILYVYGYNYLRSQCAYDVAPGGSLASVYHLTRIQYGIDNPEEVCIKVFAQKDNPRIPSVFWIWRSADFQERESYDMVGISYDNHPRLKRILMPESWIGWPLRKDYITPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: H2A_NEOFI
Sequence: MTGGKSGGKASGSKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTPKSGKGPSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AGRG6_DANRE
Sequence: MISFISGRWWRWKFQNTLAVFLLLICLSTSVAQSCQSSTSCNVVLTDSQGSFTSPCYPNDYPPSQSCNWTIQAPAGFIVQITFLDFELEEAQGCIYDRVVVKTGTSDAKFCGLTANGLTLNSTGNVMEVFFNSDFSVQKKGFHISYKQVAVTLRNQKVTMPKSSKTILRVSNSISIPVLTAFTVCFEIARTAQKATETIFTLSDAAGTSILAFEKTSNGMELFIGASYCSVDNLLTSSDITATMKPLCLTWTKSSGLIGVYFGGHYFSSICSASQIYTLQSGGLLQIAGKGSSSVSVDDQNLDGFIYNFRLWDHAMLSSELSALTCDTVGNVVDWDHSYWTIPGSSTQTDSTLSCSTAITTLSPGTAGCASGLGCPATLTVTITSIATTNIIPTNATTHEDIFYRSTLVVTDEQTPDRDATAIISQWLNQTFQNWMYRVYVDGISLQLITVLSRITTTRQTYLALLVYKNTTDVNLAEVEIESMLRSAPAIGNGLTLDSVTVNLMENCQADEFPVHYRWPESRPTVTQYVPCFPYKDRNASRTCMINRDNYTSFWALPDRGNCTNITSITVSQENAMDVAVQLADISNNGLSKEELTQVVTKVMELVNIAKINATLASTVVTIISNVMVSSEDAQKDASETALKAVDELVQKIEFDGPSLTISSKNLVVGVSALDTTNFNGSTLSAFIATNTTDPQIDFDSEAHNALAVVTLPPTLLQNLSLSQIEKVSRINFMFFGRTGLFQDHQNNGLTLNSYVVASSVGNFTIKNLQDPVRIEIAHLEYQKDPNPQCVFWDFNLQNYSGGCNSDGCKVGSDSNSNRTVCLCNHLTHFGILMDVSRAAELIDEKNNRVLTFITYIGCGISAIFSAATLLTYIAFEKLRRDYPSKILMNLSTSLLFLNMVFLLDGWLASYEIKELCVTVAVFLHFFLLTSFTWMGLESIHMYIALVKVFNTYIRRYILKFCIVGWGVPAAIVGIVLAVSKDSYGKNYYGKGKDGQGTSEFCWILNPVVFYVTCVAYFSIIFLMNVAMFIVVMIQICGRNGKRSNRTLREDILRNLRSVVSLTFLLGMTWGFAFFAWGPVSLAFMYLFTIFNSLQGLFIFVFHCALKENVQKQWRRYLCCGKLRLADNSDWSKTATNNTKKVSSDNLGKSLSSSSFGSTTANWTSKAKATLNPFARHSNADSTLQ
What is the function of this protein?
Plays an important role in heart development (PubMed:24082093).  Necessary and sufficient for axon sorting by Schwann cells independently of the ADGRG6-CTF (PubMed:25695270).
What are the official names of this protein?
Adhesion G-protein coupled receptor G6, G-protein coupled receptor 126.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.