PharMolix/UniProtQA huggingface dataset:
Protein: GREA_PETMO
Sequence: MAEQVYQLTREGYEKLKREREELKKRLMGEVAERIKEARELGDLSENSEYEEAKNEQGMIDSRIKEIDYILDNAEIIENGGNHDNSTVSLGKKVKIKDYRLNREQEFVLVTPQEANIEENKISIESPIGRSLLGRKKGEVINIKTARGSSKKIEIKEIS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RBFA_BRUSI
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHTLAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRSPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_MYCCT
Sequence: MSKEIILTQEGLEELKAELKNLLEVTRPKVIEELVEARNQGDLSENADYDAARNRQAEVEARIKEVETLINRAKVIDNSKTHSTGEVKIGSTVEFLSSLDHKTKEIKIVGAIEADPFSRLISNESPIAKAILGKKIGDTVEIKDILKPYKITIKSIK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: F16A1_DECAR
Sequence: MTQQRTLARYLTEEQRNKGVITGDLKLLIEVVSRACQAISIAIGKGGLGGVLGEAGSDNVQGEAQKKLDVLSNDILLDANEWGGHLAAMASEEMDLPHLVPHRFPKGEYLLTFDPLDGSSNIDVNVSIGTIFSVLKCPEGADLSTPEAAEQAFLQPGTAQVAAGYAVYGPTTLLVLTVGDGVAVFTLDREQGQFILTLENVQIPADTKEFAINMSNQRFWEAPVQRYVAEMQVGKEGPLGKDYNMRWVASMVADVHRIMTRGGIFMYPMDSKIKGQGGKLRLMYEANPMAMLIEQAGGAATTGRQRILDIQPEKLHQRVPVILGSKNEVERVTGYHSA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS23_DICDI
Sequence: MGKPNGLKTARKLRNHRRVQRWNDKLYKKAHFGTALKANPFGGASHASGIVVSRLGIEAKQPNSAIRKCVRVQLKKNGKKITAFVPNDGCLNYIQENDKVLVAGLGRSGHSVGDIPGVRFKVVKVSSVSLIAIYRGIKDKPNV
What are the official names of this protein?
40S ribosomal protein S23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NGB_CANLF
Sequence: MERPEPELIRQSWRAVRRSPLEHGTVLFARLFDLEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDTAVTNVEDLSSLEEYLAGLGKKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPAVRAAWSQLYGAVVQAMSRGWDGD
What is the function of this protein?
Involved in oxygen transport in the brain.  Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom.  Not capable of penetrating cell membranes (By similarity).
What are the official names of this protein?
Neuroglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Perikaryon.
Protein: CYC1_DROME
Sequence: MGSGDAENGKKIFVQKCAQCHTYEVGGKHKVGPNLGGVVGRKCGTAAGYKYTDANIKKGVTWTEGNLDEYLKDPKKYIPGTKMVFAGLKKAEERADLIAFLKSNK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c-1, Cytochrome c-distal.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MNMC_LEGPL
Sequence: MSSPFVPIITADIDWRDDLPYSLQFDDIYYSAEGGINQSLYVFVEGNNLINRWQQLPTNESNVFTIAETGFGTGMNFLLTWKLWEKFAPQNARLHYISCDKHPLKKDDLIKCLQKWPELSVQTEKLIEHYPVLTPGYHHLAFSNNRITLTLMLGDVLECYEQLLFCGDINLEHQLRESYVNAWYLDGFSPSKNQSMWSDNLFTVIAMLSKESTTVATYSASSIVKTALTNAGFVINKRKGFGPKRHMICAHYEKAYSSSKKNRHTPWHINYPVTKEERTALIVGGGLAGCFIANSLAKRGWEVTILEEKEKVGCGGSANQQAVLFPKLSIYKSPFTQFMLYSFLYANDVYKELLKHYNLGELKGSLLLAHNEREKANQQSLIHWLELYPELGQLVDEKQSSELSGISLPCGGLFIPSSGWINSPELCDILIDNKRISLITGNRVQSINYNQKNWVVNDIDASVLILANGQQVNYFHETNHLPVKAIRGQMTTIQSTQESTKLKIPLCAEGHVLPALNNSHRVGASYDIGTSEPELNALDDQLNLDRLKRIAPDIIWSQNVLDHWAGIRAASPDYLPIVGPLPNALEFKEIYSELKSNSKRWIAEAAPCYPNLYVCAAFGSRGLTTIPLATEWLAGLINREISILPRKLIQAISPARFLRKKIIQGP
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2361_CLOBB
Sequence: MLVVISPAKTLDFNNINETLPMTNPKFLKEAKILVEELKNYDSYSLGKLMKTSDKLSLLNKNRFDIWNESFDNSRQCLIAFKGEVFKGMDVGSFNIEDLFYTNDHLRILSGLYGVLNPFDGVNPYRLEMGTKLSFNNYKNLYDYWKDKLKYKLIEDIKSTGNNTLVNLASYEYFKSIEGIDILDTSINIVTPIFKEYRNGKYKIVTMKAKKARGLMVSFIMKNKINNIEDLKKFDLEGYLYNEDLSNNNNLVFTLEN
What are the official names of this protein?
UPF0246 protein CLL_A2361.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: IOLD_ALKCK
Sequence: MAKTIRLTTAQALVKFLNAQYLHADGKEEPFVEGIFTIFGHGNVLGIGQALEQDAGRLNVWQGKNEQGMAHAAMAFSKQMLRKKIYAVTTSVGPGAANLVAAAGTALANNIPVLLLPADTFATRQPDPVLQQFEQEYSQAVTTNDALKPVSRYWDRITRPEQLMSSLIRAFEVMTDPGKAGPATICIAQDVEGEAYEYPEEFFRKRIHYLERRKPTEREIEEALERIRRSKRPLLVVGGGAKYSEAKEELVALSEQCGIPLVETQAGKATVAADFANNLGGLGVTGTLAANKAAREADLVIGVGTRYTDFATSSKTAFDFEHTTFLNINVSRMQTYKLDAYQVVADAKETLSLLISRLKTYRSAFGDRIAALKEEWLAERNRLKSVVFNRKTFVPEVKEHFSQEKLNEYADALGTELPQTTALLAINETIDEDSTIICSSGSLPGDLQRLWHANEPNTYHLEYGYSCMGYEISGALGIKLAEPEREVYSIVGDGSFLMLHSELITAIQYNKKINILLFDNAGFGCISNLQMDHGGGSYYCEFLTADNQVMNIDYAKVAEGYGAKTYRANTVEQLKAALKDAKKQETSTLIEMKVLPKTMTDGYESWWNVGVAEVAASQSIQDAYQARQAKLKEAKHY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: OPGH_XANC5
Sequence: MDGTVTPSPTTTAMPPVSALDAGTPTLPPEAPLAMPEQNLREGSLQVRHQRTSPPGIGVRRFYLIGGTFATTAIAVWVMLSVLWPDGISVLEGCLLGLFVLLFAWIAMSFASAVAGFVTVVARAGRKLGIDPEQPLPTLRSRTALLMPTYNEDPRRLLAGLQAIYESVAETGQLEHFDFFVLSDTTREHIGRAEELVYNELCDRVDGHGRIFYRRRADNAARKAGNVADWVRRFGGSYPQMLILDADSVMTGDTIVRLVAGMENNPDVGLIQTLPAVVNGQTLFARMQQFGGRVYGPIIAFGVAWWHGAESNYWGHNAIIRTQAFADHAGLPSLRGRKPFGGHVLSHDFVEAALMRRGGWAMHMVPYLQGSYEEGPPTLTDLLIRDRRWCQGNLQHAKVVSAKGLHWISRMHMLIGIGHYFTAPMWGLLMLIGIGIPLAGGGIDLAGDLPFSPARYWHGSSQGNAIWIFICTMFVLLAPKLLGYIALLLNPRELRACGGAFRAAVSILLETVLAALMAPVVMYLQSRGVFEVLAGKDSGWDAQVRDDGKLSWPALFRSYGGLTVFGLFMGAVAYAVSPALAAWMGPVIVGMALSIPVVALTSLRRTGMALRRAGIFCIPEELDPPKVLVRASELRRAAALEPSLI
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROA_ECOSM
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRYMLNALKALGVSYTLSADRTRCEIIGNGGPLHAKSALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGNTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPEKLKFAEIATYNDHRMAMCFSLVALSDTAVTILDPKCTAKTFPDYFEQLARISQAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_VIBVU
Sequence: MSKNFEWITPDSDLLEKEITQIQPPKKYNVVLNNDDYTPMDFVIDVLERFFSHDLDKATQIMLKVHYEGKAICGTYSAEIAETKVAQVTMYSRENEHPLLCTMEQA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: HTPG_ALIB4
Sequence: MAKHQFQTEVGQLLHLMTHSLYSNKEIFIRELVSNASDAIDKLNYLRLTDENLKDKYAQWKGEINISFDEKDKSLSIIDNGIGMNEADLIASIGTIAKSGTKSFVEALTGDAKKDSNLIGQFGVGFYSVFMVADKVDVISKKAGEEQAYKWSSTGTGEFDLTPCTKESNGTVIYIKLKDEEAGEFASKYRIKNIVEKYSNHIAYPIFLNYDEEVSEALSEEDEKAGKKPEKKIERKHEQINAATALWMQPKAKLKEQDYNDFYKSISHDSSDPMLTIHTKTEGVNEYTTLFYIPKIAPMDMYRADFQSGVKLYVKRVFITDDEKELLPTYLRFVRGIIDSEDLPLNVSREILQENRILANIKQGSVKKILAEIKKLSKDEEKYAEFVAQYIRPLKEGVYQDYTNKEAILELLRYKSSKTEAGKMTSLEAYKERANSEQKAIYYIVGENEKVLRNSPLLESYKKNDIEVLILDDKEIDEIITPAIGAFKEWEFKDITAIEPPKVEQSEEEKKEVEEKFQDILSKIKDKLGDAVKDVKVTSRLSESPSCVVKDAADAQMAAMAHMFRAMGQAMPESAPILEINPEHEIVKKLNGCADEATIEDVSWILLDQAKLSEGMEITDTVAFAQRLSRITAKAL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BURA4
Sequence: MPTINQLVRKGRQSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ASBC_BACAN
Sequence: MLIVNREEYSKSDFDLRLQAYEEMEQFQEAAGNRFALCLKDPFDIITLVFFLKEKKSSVLLIHEDTPKETAIEMAKRANCIGILYGENSDFTKLEAVNYLAEEPSLLQYSSGTTGEPKLIRRAWTEVDTEIKVYNEALNCDIDEVPIVMAPVSHSYGLICGTLSAITRGSKPIIITNKNPKFALNIVRNTEKHIVYAVPLMLHIMGSFPQGTFQFHKIMTSGAPLPEALFYKLKETTTYMMQQYGCSEAGCISICHDMKSHLDLGNPLPHASISIGSDENAPEEIIVKMNDKEIFTKDLGYKSERGLHFMGRMDDVINVSGLKVFPIEVEETMLRLEGVQEAIVYRGKHPVMGEIVKAKVISHIDPVQIREWCMQHLPSYKVPHEIESVTEIPKNKTGKVSRKLLEMGEVTT
What is the function of this protein?
Involved in the biosynthesis of petrobactin, a catecholate siderophore that functions in both iron acquisition and virulence (PubMed:17189355, PubMed:17346033).  Catalyzes the adenylation of 3,4-dihydroxybenzoate (3,4-DHBA) to the corresponding AMP ester, followed by the transfer of the activated unit to the phosphopantetheine thiol of the aryl-carrier protein AsbD (PubMed:17346033).
What are the official names of this protein?
3,4-dihydroxybenzoate--[aryl-carrier protein] ligase, 3,4-dihydroxybenzoic acid-AMP ligase, Petrobactin biosynthesis protein AsbC.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TRUB_ALISL
Sequence: MARRRKGRPIDGVILIDKPAGITSNDTLQKVKRIYFAEKAGHTGALDPLATGMLPLCFGEATKFSQFLLDSDKRYRVVAKLGERTNTSDSDGEVVETREVKVDRGQLERCIAKFRGTTDQIPSMFSALKHEGRPLYEYAREGIEVPRKSRKITVYSIELIRFEGHEVEMEVHCSKGTYIRTITDDLGEMLGCGAHVTYLRRTGVSNYPYENMVTIEHLEALLEKAHREEISPRELLDPLLMPMDSAVQDLPEVNMITELADHVLHGQPVQVFGAPQDGIVRMTSGEERLFIGIGHIDDDGRVAPKRLVVFRDEIEEDK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CHDC_BACC7
Sequence: MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNDVAAAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: NUSB_STAAN
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MCEL_VACCT
Sequence: MDANVVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGVKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNEKVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSNGLYCYFTHLGYIIRYPVKRIIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAINDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFVEYKKFSNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDIFNEDKLSDVGHQYANNDKFRLNPAVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFKIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRIVVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTRNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR
What is the function of this protein?
Catalytic subunit of the mRNA capping enzyme which catalyzes three enzymatic reactions: the 5' triphosphate end of the pre-mRNA is hydrolyzed to a diphosphate by RNA 5' triphosphatase; the diphosphate RNA end is capped with GMP by RNA guanylyltransferase and the GpppN cap is methylated by RNA (guanine-N7) methyltransferase.  Heterodimeric mRNA capping enzyme catalyzes the linkage of a N7-methyl-guanosine moiety to the first transcribed nucleotide (cap 0 structure), whereas the methyltransferase OPG102 is responsible for a second methylation at the 2'-O position of the ribose (cap 1 structure).  Also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I/OPG123 and the RAP94/OPG109 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94/OPG109, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA.
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme D1 subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: MTLD_ECO27
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGTLPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANNEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RECA_NITMU
Sequence: MDENRSKALAAALSQIEKQFGKGSIMRLGASDVGKDVQVISTGSLGLDIALGVGGLPRGRIVEIYGPESSGKTTLTLQVIAEMQRMGGTAAFIDAEHALDSQYAQKLGVNVQDLLISQPDNGEQALEIADMLVRSGSIDVVVVDSVAALTPRAEIEGEMGEPQMGLHARLMSQALRKLTGNIKRSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGSIKKGEEVIGSETRVKVVKNKVAPPFRQAEFDILYGEGISREGEIIELGVQHKLIDKSGAWYAYKGDKIGQGKDNVREYLKEHRDIAMEIESKIRAAVGVSNPAEPAPVE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPPD_SALTY
Sequence: MSLSETATQAPQPANVLLEVNDLRVTFATPDGDVTAVNDLNFTLRAGETLGIVGESGSGKSQTAFALMGLLATNGRIGGSATFNGREILNLPERELNTLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPVHPYSIGLLNAVPRLDSEGAEMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNNAPPLEAFSPGRLRACFKPVEELL
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Oligopeptide transport ATP-binding protein OppD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BCS1_YEAST
Sequence: MSDKPIDIQYDKQATPNLSGVITPPTNETGNDSVREKLSKLVGDAMSNNPYFAAGGGLMILGTGLAVARSGIIKASRVLYRQMIVDLEIQSKDKSYAWFLTWMAKHPQRVSRHLSVRTNYIQHDNGSVSTKFSLVPGPGNHWIRYKGAFILIKRERSAKMIDIANGSPFETVTLTTLYRDKHLFDDILNEAKDIALKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGILDDVYDFMKNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSENNLTDDRLNHLMNNMPERSILLLEDIDAAFNKRSQTGEQGFHSSVTFSGLLNALDGVTSSEETITFMTTNHPEKLDAAIMRPGRIDYKVFVGNATPYQVEKMFMKFYPGETDICKKFVNSVKELDITVSTAQLQGLFVMNKDAPHDALKMVSSLRNANHIF
What is the function of this protein?
Essential for the expression of the Rieske iron-sulfur protein.
What are the official names of this protein?
Mitochondrial chaperone BCS1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SYM_NITOC
Sequence: MPRRILVTSALPYANGPIHLGHLVEYIQTDIWVRFQRMRGHECYYVCADDAHGTPIMLRAQQEGVTPETLIDQCSQEHQADFADFAISFDSYHSTHSAENRTLSETIYLRNRDKGHITTRIVRQAYDPVKGMFLPDRFIRGTCPRCDALDQYGDNCEVCGATYSPTELKEAISVLSGTPPIERESEHYFFKLNDFEPLLKRWTQGGHLQPEMANKLNEWFEAGLQDWDISRDAPYFGFPIPESTDKYFYVWLDAPIGYLASFKHLCDREGLDFDSFMTPHSTAELYHFIGKDILYFHALFWPAMLHGAGFRLPTAIFAHGFLTVNGQKMSKSRGTFIKARTYLKHLNPEYLRYYFAAKLGSGIEDLDLNFDDFMSRVNADLVGKVINIASRCAGFINKHFQNRLADRLVEKSLFQKFVAASEHLAQHYEAREFGHAMREIMALADQANRYIDEQQPWVAIKDPERKQEVQEVCTLGLNLFRQLMIYLKPVLPMTTEKAEAFFNSQSLTWSDVDTPLLNHTINRFEPLMIRAEKIKIEAMIEDSKEHLQQNTNAVKPTALLAEHPIAETIQFESFAKLDLRIARILKAEQVEGADKLLRLELDLDGETRQVFAGIKAAYAPESLVGRLTVMVANLAPRKMRFGISEGMVLAAGPGGKEIYLLNPDEGARPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.