PharMolix/UniProtQA huggingface dataset:
Protein: EFP_LISIN
Sequence: MISVNDFKTGLTIEVDNGIWRVLDFQHVKPGKGAAFVRSKLRNLRTGAIQEKTFRGGEKVAKAQIDNRKMAYLYADGTNHVFMDNESYEQIELPEDQIAHELKFLKENMEINIIMYQGETIGIDLPNTVELVVTATDPGIKGDTSSGGSKPATLETGLVVQVPFFVNEGDKLVINTTEAAYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_AERS4
Sequence: MKVKTRFAPSPTGFLHVGGARTALYSWLFAKSQGGEFVLRIEDTDLERSTQEAIDAIIEGMEWLELNWDEGPYYQTKRFDRYNGIIDEMLTDGRAYKCYCSRERLDALREGQMASGEKPRYDGKCRDSAHDHPADAPHVIRFRNPTEGSVVFDDHVRGRIEFANTELDDLIIRRTDGAPTYNFCVVVDDWDMEITHVVRGEDHINNTPRQINIYKALNAPVPEFAHVSMILGDDGAKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTLDEMIKLFSLDAISKSASAFNTDKLLWLNNHYMRSLDPAYVAKHLAWHMENQKIDTSKGPSLPEVVTLLAERCNTLVEMAAQSRYLFEDFEAIDEAAAKKHLRGVAAEPLALAKAKLTALDTWTTEALHELIEATAAELGQGMGKVGMPLRVAVTGLGQSPGIDAVMALVGKERVLARIDRALAYIEARMAAE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEM46_SCHPO
Sequence: MAGSLSSAIFNVLKYSGMASLAVTLIALGFLYKYQKTLVYPSAFPQGSRENVPTPKEFNMEYERIELRTRDKVTLDSYLMLQSESPESRPTLLYFHANAGNMGHRLPIARVFYSALNMNVFIISYRGYGKSTGSPSEAGLKIDSQTALEYLMEHPICSKTKIVVYGQSIGGAVAIALTAKNQDRISALILENTFTSIKDMIPTVFPYGGSIISRFCTEIWSSQDEIRKIKKLPVLFLSGEKDEIVPPPQMVLLFGLCGSAKKKFHSFPKCTHNDTCLGDGYFQVIADFLAENDINTPAS
What is the function of this protein?
Suppressor of bem1/bud5.
What are the official names of this protein?
Protein bem46.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LIPA_MICLC
Sequence: MSLAPEGRRLLRVEARNAEVPVERKPEWIKAKVHMGPEYIGLKNKVKSAGLHTVCEEAGCPNIFECWEDREATFLIGGDICTRRCDFCDITSGKPRPLDMEEPQKVAENIREMDLRYATVTGVARDDQKDGAAWLYAETIRRIHALNPGTGVEILPPDFGAVPELVQQVFDARPEVFAHNLETVPRIFKRIRPAFTYEKSLRVLTMAKADGLVTKSNLILGMGEEDHEIDQALVDLHESGCDIITITQYVRPSKLHHPIDRWVKPQEFVQWSQRAEEIGFQGVMAGPLVRSSYRAGKLYAQAMQRLGRTLPENLAHLAGEKTARQEASAVVAQMS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ZYMMO
Sequence: MAKLSKKAKAIAAAVDKNKLYTVAEAIALVREYATSKFDETIELAVNLGVDPRHADQMVRGVVTLPKGTGKNVRVGVFARGPKAEEAKAAGAEVVGAEDLMEAIQGGSIDFDRCIATPDMMGVVGRLGKILGPKGMMPNPKLGTVTMNVADAVKAAKGGQVEYRVDRTGIIHSGIGKASFSAEDIRANFDALIDALLKAKPAGAKGRYVKKVAISSTMGPGVSIDIADLPAAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS11_ACIC1
Sequence: MPPKTRSQTGAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPSGAVIAWASAGQVGFKGSRKSTPFAAQMTAEAAARRAQEHGMRKVDVFVKGPGSGRETAIRSLQAVGLEVGSIQDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: METK_XANC5
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAWIDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVDRKNPEQQGAGDQGLMFGYATNETDSFMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGVATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPVGDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEVQVSYAIGVAEPTSISVTTFGTGKIADEQIEKLIRKHFDLRPFGIIQMLDLIHPMYQQTASYGHFGRKPKDFTYTDGTGAQHSATSFSWEKTDRADALRAAAKLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_CHLSY
Sequence: MGKLRVTYVKSAIGYARDQKETLAALGLRRLNQSVLKPDNPSVRGMLFKVQHLVKVEEVEDEVQA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL10E_SACS2
Sequence: MPLRPGRCYRHFSGPAYTRKEYIPGIPQPKITKFTSGNPNGDYDYEVRLITTEIGQIRHNALEAVRTLTLKTLSKKTGSETSFFMWILKYPHHVLRENKMMAFAGADRLQDGMRLSFGTPIGTAARIEKLGETLIVIKVKKEHLEFAKEALKIASKKLPLRTRIEIIPLRLVRQEVQS
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PSTB_COREF
Sequence: MSKLKLNDVNIYYGDFHAVQNVNLEVPARSVTAFIGPSGCGKSTVLRSINRMHEVIPGAYVEGEILLDGENIYGPKIDPVAVRNTIGMVFQKANPFPTMSIEDNVVAGLRLSGEKNKKKLKEVAEQSLRGANLWEEVKDRLDKPGGGLSGGQQQRLCIARAIAVKPEVLLMDEPCSALDPISTLAVEDLIHELKEEFTIVIVTHNMQQAARVSDQTAFYSLEATGKPGRLVELGPTKKIFENPDNKETEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IFT25_CHLRE
Sequence: MKDYAREENGGLVVMASCSDERFPPENMLDGKDNTFWVTTGMFPQEFVLRLESCIRVSKITTLSLNVRKLAVEKCDQDKPDQFEKVFEVELANRGDRLQTEVHQVNIRAKYLKFILLQGHGEFATVNRVSVVGGDDDGGGYDEPGGGYGSMQRQPSMGYGGGGGSAATGFAADPGNAAAGGGGGFEDEF
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B.  Forms a subcomplex within the IFT complex B with IFT27.
What are the official names of this protein?
Intraflagellar transport protein 25, Flagellar-associated protein 232.
What is the protein family that this protein belongs to?
Belongs to the IFT25 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Note=Colocalizes with IFT27 at the distal-most portion of basal bodies, probably the transition zones, and concentrates in the basal body region.
Protein: P2C61_ARATH
Sequence: MGFCFCLSSGGSTDKSQIYEITDYGQENAVLYSDHHVVPQNLGSVSSLAGGKGLNQDAAILHLGYGTEEGALCGVFDGHGPRGAFVSKNVRNQLPSILLGHMNNHSVTRDWKLICETSCLEMDKRILKVKKIHDCSASGTTAVLAVKHGNQVMVANLGDSRAVMIGTSEDGETKVAQLTNDLKPSVPSEAERIRKRNGRVLALESEPHILRVWLPTENRPGLAMSRAFGDFLLKSYGVIATPQVSTHQITSSDQFLLLASDGVWDVLSNEEVATVVMKSASEAGAANEVAEAATNAWIQKFPTVKIDDISVVCLSLNKKHNPQPQI
What are the official names of this protein?
Probable protein phosphatase 2C 61, AtPP2C61.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: MIGA2_BOVIN
Sequence: MAFRRTEGMSMIQALAMTVAEIPVFLYTTFGQSAFSQLRLTPGLRKVLFATALGTVALALAAHQLKRRRRKKKQVGPEMGGEHLGTVPLPILMARKVPSVKKGYSNRRVQSPSSKSNDTLSGISSIEPSKHSGSSHSLASMVVVNSSSPTAACSGPWETRGIEESVTTADGNAESLYMQGMELFEEALQKWEQALSVGQRGDSGSTPTPGDGLRNPETASEALSEPESQRKEFAEKLESLLHRAYHLQEEFGSTFPADSMLLDLERTLMLPLTEGSLRLRADDGDSLTSEDSFFSATELFESLQVGDYPIPLSRPAAAYEEALQLVKEGKVPCRTLRTELLGCYSDQDFLAKLHCVRQAFEGLLEDKSHQLFFGEVGRQMVTGLMTKAEKSPKGFLESYEEMLSYALRPETWATTRLELEGRGVVCMSFFDIVLDFILMDAFEDLENPPSSVLAVLRNRWLSDSFKETALATACWSVLKAKRRLLMVPDGFISHFYSVSEHVSPVLAFGFLGPKPQLSEVCAFFKHQIVQYLTDMFDLDNVRYTSVPALAEDILQLSRRRSEILLGYLGVPAASSIGLNGVLPRENGPPEALQ
What is the function of this protein?
Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers.  May act by regulating phospholipid metabolism via PLD6/MitoPLD.
What are the official names of this protein?
Mitoguardin 2, Protein FAM73B.
What is the protein family that this protein belongs to?
Belongs to the mitoguardin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: MTLD_STRZJ
Sequence: MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEKGKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELLAKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAVDRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHKVIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFDYRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL18_RHOBA
Sequence: MDKNKKLQSKRLRRRRHVRNKLRGSADQPRLCIQRTLKHFACQVVDDQAGKTLLSASTRDKTVRDQVKAGGNCDAAALVGKLVAEKAAEAGVKTVKLDRGHNKYHGRVKAFADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FEOB_STAAN
Sequence: MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNVQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKYLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVAEQVGAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVAYPLVTAYVLTFIFYQVGHLFV
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_COREF
Sequence: MANIKSQIKRNKTNEKARLRNQAIRSAVRTEIRKFHAAIDGGDKAAAESQLRVASRALDKAVTKGVFHRNNAANKKSSLARAFNKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NU5M_DEBHA
Sequence: MAWLIYFFEEPISIHLGTWFSVGDIQVNYGTLLDSLSMVVMVPVGIVTLSVLIYAIDYMRYDPNRNRFYIILSVFAIFMTVLVISDNYIMMFMGWEFVGVVSYLLISFWNTRIAAMKSALSAILLNRMGDTLFVICIGTMLSYFHAVDFETMELMTPHTDTYMLNLMAMMLLMAATAKSAQLGLHGWLLSAMEGPTPVSALTHAATMVCSGVFVLVRSSFMLEYTPSMLLVMLWLAGFTTLMSGLMAVVSNDMKRVMALSTMSQLAMMMLAMGSSAYDLAMYHLYCHAFFKALLFMSAGSIMHSYMSETQDMRKYGGLINYLPFSYTTMLMASLSLMAMPGLTGYYSKDIIMESLYGTYTVSGYIMYYIATASATLTAIYSLRVTYLTFYNVPRSNKYTFAHVHESTHMAMPMFILTIYSMFLGYARDNVTFHLVMGLPHTNSFIETEYTLPAMFKLLPLMLGLSLSLTTVYMYEFTYKMSKSSVYNYFNQRIYYDQLTNNLIMRPVLKLGGATNAYTDNGLLRVLGSTGMSRALINIPVLLMMNMTYTFIVFFTYMKYFYIIPATRGRKLYMILYTKCMINIFHTPEAGII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPB_AFIC5
Sequence: MSLPKPNSFRAGPDERGHFGTFGGRFVAETLMPLILDLEKAYAAAKADPSFQKEMNGYLKDYVGRPSPLYFAERLTEHLGGAKIYLKREELNHTGSHKVNNVLGQIMVARRMGKKRIIAETGAGQHGVATATLCARFGLECIVYMGAVDVARQEPNVIRMEMLGAKVVPVQSGTRTLKDAMNDALRDWVTNVATTFYCIGTVAGPHPYPAMVRDFQSVIGHETREQMMAAEGRLPDSLVACIGGGSNAMGLFHPFLDEPAVEIFGVEAAGHGLTNLHAASLAGGRPGVLHGNRTYLLMNEDGQIQDAHSISAGLDYPGIGPEHAWLHETGRVTYLSATDEEALAAFQLLSRLEGIIPALESAHAIAKLSQLAPKRPRDHLMVVNLSGRGDKDVPQVGDILRGRKS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: IF2B_METST
Sequence: MAKENAEFKEYEKLLDQAYEQLPDKIFEAKRFKVPKGYSVIQGNRTIIKNFGDVSRTLNRDPQHVLKYLLRELGTSGNVEGNRAILQGKFTHYVINDRVKEYVDNFVMCHECNRPDTVIIREDRIDMLKCSACGARAPLKSL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: NS7B_BC279
Sequence: MNELTLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDIEEPCNKV
What are the official names of this protein?
Non-structural protein 7b, ns7b, Accessory protein 7b.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HMCT_HELPY
Sequence: MQEYHIHNLDCPDCASKLERDLNELDYVKKAQINFSTSKLFLDTSDFEKVKAFIKQNEPHLSLSFKEATEKPLSFTPLIITIMVFLGAILILHLNPSPLIEKAMFFVLALVYLVSGKDVILGAFRGLRKGQFFDENALMLIATIAAFFVGAYEESVSIMVFYSAGEFLQKLAVSRSKKSLKALVDVAPNLAYLKKGDELVSVAPEDLRVNDIVVVKVGEKVPVDGVVVKGESLLDERALSGESMPVNVSENSKVLGGSLNLKAVLEIQVEKMYKDSSIAKVVDLVQQATNEKSETEKFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLGYFGGVGAASRKGILMKGVHVLEVLTQAKSIAFDKTGTLTKGVFKVTDIVPQNGHSKEEVLHYASCSQLLSTHPIALSIQKACEEMLKDDKHQHDIKNYEEVSGMGVKAQCHTDLIIAGNEKMLDQFHIAHSPSKENGTIVHVAFNQTYVGYIVISDEIKDDAIECLRDLKVQGIENFCILSGDRKSATESIAQTLGCEYHASLLPEEKTSVFKTFKERYKAPAIFVGDGINDAPTLASADVGIGMGKGSELSKQSADIVITNDSLNSLVKVLAIAKKTKSIIWQNILFALGIKAVFIVLGLMGVASLWEAVFGDVGVTLLALANSMRAMRA
What is the function of this protein?
Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell.  This ion efflux may influence the activity of urease, which is essential for the survival of the bacterium in the gastric environment.
What are the official names of this protein?
Cadmium, zinc and cobalt-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TMOD_PSEME
Sequence: MSTLADQALHNNNVGPIIRAGDLVEPVIETAEIDNPGKEITVEDRRAYVRIAAEGELILTRKTLEEQLGRPFNMQELEINLASFAGQIQADEDQIRFYFDKTM
What is the function of this protein?
Effector component of the toluene-4-monooxygenase multicomponent enzyme system which catalyzes the O2- and NADH-dependent hydroxylation of toluene to form p-cresol (PubMed:1885512, PubMed:15240250, PubMed:11297417, PubMed:15882052, PubMed:19033467).  Required for optimal efficiency and specificity of the holoenzyme (PubMed:15882052, PubMed:19033467).
What are the official names of this protein?
Toluene-4-monooxygenase system, effector component, T4MO, Toluene-4-monooxygenase effector protein, Toluene-4-monooxygenase system protein D, T4moD.
What is the protein family that this protein belongs to?
Belongs to the TmoD/XamoD family.
Protein: LEU1_YERPB
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: TANC1_RAT
Sequence: MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV
What is the function of this protein?
May be a scaffold component in the postsynaptic density.
What are the official names of this protein?
Protein TANC1, TPR domain, ankyrin-repeat and coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TANC family.
What are the subcellular locations of this protein?
Postsynaptic density. Note=Largly colocalizes with SYP/synaptophysin, DLG1, DLG4 and GRIA1 at synaptic sites.
Protein: GLMM_RALSO
Sequence: MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGSEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETESQIEAELEKPMVYAASDALGRARRIDDAAGRYIEFCKSTFPNDLNLFGMKIVLDSAHGAAYHIAPHVFHELGAEVVSIGNQPNGRNINDGYGATEPAKLIEATRQHGADLGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQAVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEELKKHGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLEQVLDGVHLFPQKLINVRVEKGFDWKAHAALQAALKVSEAELNGKGRVLIRPSGTEPVVRVMVEAQDAALATKYAEQLAATLQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL9_PARMW
Sequence: MPKRVQVVLNEDVLSLGKDGDLVEVAPGYARNFLLPFGKAVPVTPAVMKQVEHRRAKEAERQAALKQAALDFRTALDTIGRFTVKKQTGEDNVLFGTVTNGDVAEAIQDATKKEIDRRDIVVPEIHRTGKYSVTVKLHSEVTAEINLEVVSY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DDIT3_BOVIN
Sequence: MAAESLPFSFGALSSWELEAWYEDLQEVLSSDENRGTCVSPPGNKEEESKSFTTLDPASLAWLTEEPGPPEVTHTSQSPCSPESSQSSLAQEEEEEDQGRTRKRKQSGQSPARAGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQA
What is the function of this protein?
Multifunctional transcription factor in ER stress response.  Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress.  Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes.  Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes.  Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L.  Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG).  Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity.  Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response (By similarity).
What are the official names of this protein?
DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP zeta, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, CCAAT/enhancer-binding protein homologous protein, Growth arrest and DNA-damage-inducible protein GADD153.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation.