PharMolix/UniProtQA huggingface dataset:
Protein: DOT5_YEAST
Sequence: MGEALRRSTRIAISKRMLEEEESKLAPISTPEVPKKKIKTGPKHNANQAVVQEANRSSDVNELEIGDPIPDLSLLNEDNDSISLKKITENNRVVVFFVYPRASTPGCTRQACGFRDNYQELKKYAAVFGLSADSVTSQKKFQSKQNLPYHLLSDPKREFIGLLGAKKTPLSGSIRSHFIFVDGKLKFKRVKISPEVSVNDAKKEVLEVAEKFKEE
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes.  Also has a role in the regulation of telomere length.  Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth.  Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide.  Acts as an antioxidant necessary for stationary phase survival.
What are the official names of this protein?
Peroxiredoxin DOT5, Prx, Disrupter of telomere silencing protein 5, Nuclear thiol peroxidase, nTPx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin DOT5.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: LSM7_MOUSE
Sequence: MADKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTMEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm7.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSPA_STAA2
Sequence: MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNIAEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFYGSIEDLEKIQSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGGPHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDKPIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: IDGF1_DROSI
Sequence: MRFQLFYILGLLSVTSLTQAANNLVCYYDSTSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGTLELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGTYWKSFKKLFTGDFVVDPLAEQHKSQFTDLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADYTAPIFFQDEQNRLPHLNVEFQVNYWLQNHCPGQKLNLGIASYGRAWKLSKESGLSGAPIVHETCGAAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADENGDFGVWLSFDDPDFAGIKAVYAKSKGLGGIALFDLSYDDFRGLCTGQKYPIVRSIKYFMG
What is the function of this protein?
Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells.  May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity).
What are the official names of this protein?
Chitinase-like protein Idgf1, Imaginal disk growth factor protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. IDGF subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in hemolymph. It is probably transported to target tissues via hemolymph.
Protein: RL11_MYCTU
Sequence: MAPKKKVAGLIKLQIVAGQANPAPPVGPALGQHGVNIMEFCKAYNAATENQRGNVIPVEITVYEDRSFTFTLKTPPAAKLLLKAAGVAKGSAEPHKTKVAKVTWDQVREIAETKKTDLNANDVDAAAKIIAGTARSMGITVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MATK_PINRI
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFQEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKSSVEGMNESKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYEYRNSPDNLQRSIIVVPRVNTRFFLFLWNYYVCECESILFSRLKRSSHSRSLSHGSFPHRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGAHLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPILVRTKMLDELFIADLITDEIDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFYSLRFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYB_CORCD
Sequence: MALNLRKNHPLLKIINNSLVDLPTPSNISAWWNFGSLLGLCLITQIVTGLLLAMHYTADTSLAFTSVSHMCRDVQFGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLNKETWNIGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWLWGGFSVDNPTLTRFFAFHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDLLGFALMLIPFITLALFSPNLLGDPENFTPANPLTTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLMPLLHVSKQRSMTFRPLSQILFWTLVADLCILTWVGSQPVEHPFIIIGQLASFTYFAIILILFPIAGVLENKMLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL18_DICT6
Sequence: MIIKRSRKELRKIRHLRIRKKIIGTSERPRLAVYKSLRYIYAQIIDDTKGHTLVSASSLEKEIRSQLKSTKNIEAAKLVGEVIAKRALEKGIKKVVFDRGGFLYHGKVKALADSARAAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: NDUS5_PONAB
Sequence: MPFLDIQKRFGLNIDRWLTTQSAEQPYKMASRCHAFEKEWIECAHGIGYTRAEKECKIEYDDFIECLLRQKTMRRTGTIRKQRDKLIKEGKYTPPPHHIGKGEPRP
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5, Complex I-15 kDa, CI-15 kDa, NADH-ubiquinone oxidoreductase 15 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: RPPH_ECO81
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PSY_NARPS
Sequence: MVVAILRVVSAIEIPIRLGFSEANWRFSSPKYDNLGRKKSRLSVYSLYTTSKYACVGFEAENNGKFLIRSSLVANPAGEATISSEQKVYDVVLKQAALVKDQTKSSRKSTDVKPDIVLPGTVYLLKDAYDRCGEVCAEYAKTFYLGTLLMTPERRRAIWAIYVWCRRTDELVDGHNASHITPSALDRWEARLEDLFAGRPYDMFDAALSDTVSRFPVDIQPFMDMVEGMRMDLKKSRYKNFDELYLYCYYVAGTVGLMSVPVMGIAPESLAEAESVYNAALALGIANQLTNILRDVGEDARRGRIYLPQDELAEAGLSDEDVFTGKVTDKWRSFMKRQIKRARTFFEQAEKGVTELSQASRWPVWASLLLYRQILDEIEANDYNNFTKRAYVSKVKRLAALPLAYGKSLLIPLSLRPPSLSKA
What is the function of this protein?
Catalyzes the reaction from prephytoene diphosphate to phytoene.
What are the official names of this protein?
Phytoene synthase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMG_HELPY
Sequence: MNPLLQDYARILLEWNQTHNLSGAKNLSELEPQITDALKPLEFIKDFKSCLDIGSGAGLPAIPLALEKPEVKFILLEPRIKRAAFLNYLKSVLPLKNIEIIKKRLEDYQNLLQVDLITSRAVASSSFLIEKSQRFLKDKGYFLFYKGEQLKDEIACKDTECFMHQKRVYFYKSKESLC
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFC_AEDAE
Sequence: MRTLTVVCFVALCLSAIFTTGNALPGELADDVRPYANSLFDELPEESYQAAVENFRLKRATCDLLSGFGVGDSACAAHCIARRNRGGYCNAKKVCVCRN
What is the function of this protein?
Antibacterial peptide mostly active against Gram-positive bacteria.
What are the official names of this protein?
Defensin-C.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_PHYAS
Sequence: MPTVSQLIKKRRTSKTTKTKAPALSYGFNILKKKAQHYASPQKMGVCLRVTTMTPKKPNSALRKFARVRLSNGSEVTAYIPGVGHSLQEHSSVLICGGRVKDLPGVRYHIIRGTLDATGVANRKQGRSRYGAKRPKAQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RK24_THAPS
Sequence: MPKGKNLHVKIGDNVKIISGFDKNKTGEVTKIYRNTGKILVKGINFKFKHIKPNTESDVGEIKQFEAPIHHSNVKLI
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PP273_ARATH
Sequence: MSISKAAFLNHLQTLSRSYRHRVLPQPFLAVRYMSFATQEEAAAERRRRKRRLRMEPPVNSFNRSQQQQSQIPRPIQNPNIPKLPESVSALVGKRLDLHNHILKLIRENDLEEAALYTRHSVYSNCRPTIFTVNTVLAAQLRQAKYGALLQLHGFINQAGIAPNIITYNLIFQAYLDVRKPEIALEHYKLFIDNAPLNPSIATFRILVKGLVSNDNLEKAMEIKEDMAVKGFVVDPVVYSYLMMGCVKNSDADGVLKLYQELKEKLGGFVDDGVVYGQLMKGYFMKEMEKEAMECYEEAVGENSKVRMSAMAYNYVLEALSENGKFDEALKLFDAVKKEHNPPRHLAVNLGTFNVMVNGYCAGGKFEEAMEVFRQMGDFKCSPDTLSFNNLMNQLCDNELLAEAEKLYGEMEEKNVKPDEYTYGLLMDTCFKEGKIDEGAAYYKTMVESNLRPNLAVYNRLQDQLIKAGKLDDAKSFFDMMVSKLKMDDEAYKFIMRALSEAGRLDEMLKIVDEMLDDDTVRVSEELQEFVKEELRKGGREGDLEKLMEEKERLKAEAKAKELADAEEKKKAQSINIAALIPPKAVEEKKETAKLLWENEAGGVEEADVVEMAKGVEAGGSNGQDPPSC
What is the function of this protein?
May play a role in embryogenesis.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g49240, mitochondrial, Protein EMBRYO DEFECTIVE 1796.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: QUEA_CAMJE
Sequence: MNKDLLLSSYDYTLANELIANYPTNPKEDARLLVFDRKNKEIFHTTFKNLQDFLPNCAIFFNDTKVIKARIYGNKASGGKIELFLHQPFLNSHNPLFLAQIKGRIKKDEILYFKEDLKVRVVELLNDGLRKVQFFQNDKTLDTSNLYNLLDKIGHIPLPPYIKREDEKSDLKDYQSIFAKNLGAVAAPTASLHFSETMLENLRKKHEIYHLTLHVGAGTFKSVECENIQEHKMHSEFFNIPQQACEIIDSKQAILGVGTTVTRTIEYYTRTKTKNGFCDLFLHPQNPPIRQNHLLTNFHLPKSTLIMLVSAFIGREQCLKLYELAIKEKYRFYSYGDAMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7050_RICRS
Sequence: MKKLLLIAATSATILSSSVSFAEGMDHEWYLRIDTGAAMFNEEKDKATGVKLKSNTTVPVALGIGYYISENFRADLTLGTIIGGKLKKSGAATNAPFTRTNVSASHKPTITRLLINGYVDLTNFDMFDVFAGAGVGPALVKEKITYNGITGLSSNTKNRTNISYKLTLGTSAQIVDGVKVELAYSWIDDGRTKSKNVIYQGTSVPTGGMHYQSHNLTAGIRFDI
What are the official names of this protein?
Putative adhesin A1G_07050.
Protein: CTR1_ANOGA
Sequence: MLRKVFAVVSVLLVVSAAKVTKLVLDDNYVNRVVGGEVAKNGSAPYQVSLQVPGWGHNCGGSLLNDRWVLTAAHCLVGHAPGDLMVLVGTNSLKEGGELLKVDKLLYHSRYNLPRFHNDIGLVRLEQPVRFSELVQSVEYSEKAVPANATVRLTGWGHTSANGPSPTLLQSLNVVTLSNEDCNKKGGDPGYTDVGHLCTLTKTGEGACNGDSGGPLVYEGKLVGVVNFGVPCALGYPDGFARVSYYHDWVRTTMANNSK
What are the official names of this protein?
Chymotrypsin-1, AnChym1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: LEPR_PIG
Sequence: MTCPKFSVALLHWEFIYVITAFDLAYPITPWKFKLSCMPPNTTYDFLLPAGISKNTSTLNGHDEAVVETELNSSGTYLSNLSSKTTFHCCFWSEEDKNCSVHADNIAGKAFVSAVNSLVFQQTGANWNIQCWMKEDLKLFICYMESLFKNPFKNYDLKVHLLYVLLEVLEGSPLLPQKGSFQSVQCNCSARECCECHVPVSAAKLNYTLLMYLKITSGGAVFHSPLMSVQPINVVKPDPPLGLHMEITDTGNLKISWSSPTLVPFQLQYQVKYSENSTTNMREADEIVSDTSLLVDSVLPGSSYEVQVRGKRLDGPGIWSDWSTPFTFTTQDVIYFPPKILTSVGSNISFHCIYKNENKIVSSKKIVWWMNLAEKIPQSQYDVVGDHVSKVTFPNMNATKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTNAIQSLVGSTLQLRYHRSSLYCSDVPSVHPISEPKDCQLQRDGFYECIFQPIFLLSGYTMWIRINHPLGSLDSPPTCVIPDSVVKPLPPSSVKAEITAKIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKIYEVYDTKLKSTSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSTPAYTVVTDVKVPIRGPEFWRIINEDATKKERNITLLWKPLMKNDSLCSVRSYVVKHHTSRHGTWSEDVGNHTKLTFLWTEQAHSVTVLAVNSIGASSANFNLTFSWPMSKVNIVQSLSAYPLNSSCVGLSWLLSPSDYNLMYFILEWKILNEDHEIKWLRIPSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDGEKHRNDAGLYVIVPIIISSSILLLGTLLMSHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTESVTFGPLLLEPETISEDISVDTSWKNKDEMVPPTTVSLLLTTPDLEKSSICISDQRSSAHFSEAESMEITREDENRRQPSIKYATLLSSPKSGETEQEQELVSSLVSRCFSSSNSLPKESFSNSSWEIETQAFFILSDQHPNMTSPHLSFSEGLDELMKFEGNFPKEHNDERSVYYLGVTSIKKRESDVFLTDESRVRCPFPAHCLFADIKILQESCSHLVENNFNLGTSGQKTFVSYMPQFQTCSTQTQKIMENKMYDLTV
What is the function of this protein?
Receptor for hormone LEP/leptin (By similarity).  On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS.  In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones.  In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic and affects innate and adaptive immunity (By similarity).  Control of energy homeostasis and melanocortin production (stimulation of POMC and full repression of AgRP transcription) is mediated by STAT3 signaling, whereas distinct signals regulate NPY and the control of fertility, growth and glucose homeostasis.  Involved in the regulation of counter-regulatory response to hypoglycemia by inhibiting neurons of the parabrachial nucleus.  Has a specific effect on T lymphocyte responses, differentially regulating the proliferation of naive and memory T-cells.  Leptin increases Th1 and suppresses Th2 cytokine production (By similarity).
What are the official names of this protein?
Leptin receptor, LEP-R, OB receptor, OB-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane.
Protein: FB23_ARATH
Sequence: MDSGKTFDSISNDLFLEILLRLSTKSIDRSRCVSKQWASILCSQDFTESEKFNFINASSFLFSSTKLINYKGKLGGIDLAYNHGGVYPVELRMWVLEDVEKHEWSRHVYSLPETIEFQQCNYNICVGGMNAIGFEDYLNRRVYAFVDYVEDLSVNDAMQLKSSSLQNG
What are the official names of this protein?
Putative F-box protein At1g30945.
Protein: ACKA_STRP2
Sequence: MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYLS1_MACFA
Sequence: MEELLPDRQVWANMDPEERMLAAATAFTHICAGQGEGDVRREAQSIQYDPYSKASIAPGKRPTLPVQLQYPHVESNVTSETVSEASQRLRKPVMKRKVLRRKPDGEVLVTDESIISESESGTENDQGLWDLRQRLMNVQFQEDKESSFDISQKFNPPHEYQGISQDQLICSLQREGMGSPAYEQDLIVASRPKSFILPKLDQLSRNRGKTDRVARYFEYKRDWDSIRLPGEDHRKELRWGVREQMLCRAEPQSKPQHIYVPNNYLVPTEKKRSALRWGVRCDLANGVIPRKLPFPLSPS
What is the function of this protein?
Plays a role in ciliogenesis.
What are the official names of this protein?
Centriolar and ciliogenesis-associated protein HYSL1, Hydrolethalus syndrome protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HYLS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: SYL_CELJU
Sequence: MQEQYNPAEVEAQAQQYWEEHQSFNVIEDPGKEKFYCLAMFPYPSGKLHMGHVRNYTITDVIARYQRMQGKNVLHPMGWDAFGLPAENAALKHNTAPAKWTYSNTDHMRNQLKQLGFGFDWSRELTTCKPEYYQWEQWFFTRLYEKGLVYKKMSTVNWDPIDQTVLANEQVIDGRGWRSGALVERKEIPQWFIKITDYAEELLNDLDKLPNWPEQVKTMQRNWIGKSRGLEMRFDLQSPVGEFTSFDIYTTRPDTLMGVTYVSLAAEHPIAKYLADSNPALAQFIADCKVQSVAEADMATMEKKGMDTGIKALHPITGEPVAVWVANYVLMDYGSGAVMAVPAHDQRDYEFAQKYHLGITQVIAPQNGETIDLSQAAFTDKGVLVNSGEYDGLDFNAAFDAIASTLEMANKGRVKTNYRLRDWGVSRQRYWGAPIPMFNLPEGGEIPVPAHKLPILLPEEVVMNGVQSPIKADPEWKKDELDGQYVERETDTFDTFMESSWYYARYTCPNFTDGMINKAAADYWLPVDQYVGGIEHAILHLLYSRFFHKLMRDEGLVSGDEPFERLLCQGMVNAESFFIKSEGKENWIEPENVVIERDDKGRFIAAKHKITGDAVEFGGVIKMSKSKANGVDPESVINQYGADTVRLFTMFAAPPEQSLEWSDSGVEGASRFLRRLWKAVEGHINAGTPGKLDAASLPQQQKDLRRKTHETIQKVSDDYGRRQTFNTAIAAVMELLNETSKLSDRANPQGLAVEREALEAAILLLAPIVPHITQALWIELGNSGIPLNQPWPTLDESALVRSTIEVVVQVNGKLRGKIDAAVDAPKELLEQIAVQQENVQKFLEGVTVRKVIVVPNKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISY1_CANGA
Sequence: MSRNVDKSQTVLALYQEHKAESRRDYNRYKRPRVESVRDPAEAREWYKQTLREVGECTNRLYDPLLSEEQVRECNARVNQLIQESQRWSRHLRRFKQRQRPPVYGGVVVNGVRYIGRARELPEARKRPTAARQFTVKRAKYVDFSDNGDFSDNGDYRGTSERLRKAHGIAQQESVLVEPPTQQQMEEYLVERRKRQLLHQLNL
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor ISY1.
What is the protein family that this protein belongs to?
Belongs to the ISY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS6_STRA1
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILSDNGATVVESKDWEKRRLAYEIQDFTEGLYHIVNVEAEDAVALNEFDRLSKINGDILRHMIVKVD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y1747_DICDI
Sequence: MASLIKEFKKLKVFLPKRMRELLIPSDEGFFDTNYRYPAPGSQTPPDITNKQFVKTRPLTRVYKFLKKRGEVLSLRKQPTLDAPTENLTAEEKAEKLFYETEPYPLTAPRIKDNKVFFHNIKAMEGFDIRNVRSINKNISKIENEFGVPIDRKVLRFEESEIDTDEPLPKSTNNLF
What are the official names of this protein?
Uncharacterized protein DDB_G0283843.
Protein: HSCA_ECO8A
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NEW14_SCHPO
Sequence: MQKKEKIIENLEKAGNTFHLIIKCNTIARILKNLSTYAILLNSNILEEHVDLLLIYLSTQRMWKLNNLKKTLQYKGSKKK
What are the official names of this protein?
Uncharacterized protein new14.