PharMolix/UniProtQA huggingface dataset:
Protein: HTPA_PARDP
Sequence: MTLDLNPNDMSHVVAADRAHVWHHLSQHKQYETIDPRVFVEGKGMRLWDATGREFLDAVSGGVWTVNVGYGRESIADAIRDQLVKLNYYAGAAGTVPGAIFAQKLIEKMPGMTRVYYSNSGSEANEKVYKMVRQIAARHHGGKKWKILYRDRDYHGTTIATLATSGQDQRAIAYGPFPDGFVRVPHCLEYRKQWDVENYGERAADAIEEVILREGPDTVGAIVLEPVTAGGGVITPPEGYWQRVQEICRKYDILLHIDEVVCGLGRTGTWFGYQQYGIEPDFVTMAKGVASGYAAISCTVTTERVFEMFKDAPEDGMSFFRDISTFGGCTSGPVAAIENMRIIEDEGLLDNTVAMGERTLANLNALMEKHKVIGDVRGKGLFCGAELVADRASKEPMDEKKVQAVVADCLAQGVIIGATNRSLPGFNNTLCLSPALIATADNIDRITDAIDNALTKVFA
What is the function of this protein?
Converts hypotaurine to alanine and sulfinoacetaldehyde, which desulfinates spontaneously to acetaldehyde and sulfite.  Can also catalyze the degradation of taurine into alanine and sulfoacetaldehyde, which is stable (PubMed:23603744).  Has 2-fold higher aminotransferase activity with hypotaurine as the substrate (PubMed:23603744).
What are the official names of this protein?
Hypotaurine/taurine--pyruvate aminotransferase, Hpa/Tpa.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: RS14_ACAM1
Sequence: MAKKGMVEREKKRQRLVAKYAHKRQALLEQISQASSQQERMDLHRQLQRLPRNSAPTRLRNRCWVTGRSRGYYRDFGLSRHVLREMAHEGLLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RLMD_BURL3
Sequence: MSEAVPTSARKSRNAPVAPGPAPVLEIESLDMEARGVGRTITEDGEPGKVIFVEGALPGERVTYSSFRRKPSYEQATVVDILRPSVMRTKPKCAFFGTCGGCSMQHLDMRAQVAVKQRVLEDNLWHLAKLRAETMFAPIHGPSWGYRYRARLTVRNVAKKGGVLVGFHEKKSSYVADMTSCEVLPPHVSAMLVPLRRLVEGLSIRDRMPQIELAVGSEVTALVLRVLEPINADDEALLRAFADEHKVQFWLQPKGPDTVAPFYPLDVSLDYTLPEFGIRMPFKPTDFTQVNHQINRVLVGRALRLLAPSRDDRVLDLFCGIGNFTLPLARLSREVMGIEGSDTLTTRALANARENGVDGHTTFACRNLFEVTGDDIRALGAFDKFLIDPPREGALAVSKALAEIAQSGEGPLPKRIVYVSCNPSTLARDAGLLVHEAGYRLKGAGVVNMFPNTSHVESIALFERD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: YFJE_BACSU
Sequence: MSEALTFESKYALLYLGGGLLAMIYGLITFFMAFPAFTSRGNVIFTIKTGPSGEIFLRKRSVLFSEVKRLYMGRHQYSLKGIFFEDIIIEKTDGKIVRIPTWNIITNPLFFEAVERYILPHLNEEAQNNWISQFTEVQRKAYLKEFENHPKL
What are the official names of this protein?
Uncharacterized protein YfjE.
What is the protein family that this protein belongs to?
To B.subtilis YfjD.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURD_CORJK
Sequence: MESTHALQPAEALETMRSQTVLVAGAGVAGRGVISMLCALGARLVLVADDNAQALGHIADDGDTELRLLSVSDAIDTLEELAPQLVVTSPGWKPESPLLARAAELNIPVIGDIAAAWLADQAGAFGQPRTWLAVTGTNGKTTTTAMLTSMLIADGRAALAVGNIGIAPSAALAAQHRGEPRSDVFVAEVSSFQLHWAPMFKPTVGCILNLAEDHLDWHGSYENYCADKAQVLTAEESVLALDDDDVLTTARAREVVARRGYTIHDPEEVASQNTERVVGVRDGRLVEVVIGDPSQTTDLAPAQGISPPGPAGLADAAASAAMARALGVAPGAIEAALAGFKVQAHRGQVVLEHGGVTWIDNSKATNPHAAEAALRGQRNVIWVAGGQLKGAAVDGLIRAIGGALKAVVALGVDRAELVAEVSRQLPDLPVTVIDATDPEEAMRAVARAAHGLAQPGDSVVLAPAAASLDMYTGMSQRGDLFAQYAVAYAGADRADERTQERG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7A53_PANGI
Sequence: MDLFISSQLLLLLVFCLFLFWNFKPSSQNKLPPGKTGWPIIGETLEFISCGQKGNPEKFVTQRMNKYSPDVFTTSLAGEKMVVFCGASGNKFIFSNENKLVVSWWPPAISKILTATIPSVEKSKALRSLIVEFLKPEALHKFISVMDRTTRQHFEDKWNGSTEVKAFAMSESLTFELACWLLFSINDPVQVQKLSHLFEKVKAGLLSLPLNFPGTAFNRGIKAANLIRKELSVVIKQRRSDKLQTRKDLLSHVMLSNGEGEKFFSEMDIADVVLNLLIASHDTTSSAMGSVVYFLADHPHIYAKVLTEQMEIAKSKGAEELLSWEDIKRMKYSRNVINEAMRLVPPSQGGFKVVTSKFSYANFIIPKGWKIFWSVYSTHKDPKYFKNPEEFDPSRFEGDGPMPFTFIPFGGGPRMCPGSEFARLEVLIFMHHLVTNFKWEKVFPNEKIIYTPFPFPENGLPIRLSPCTL
What is the function of this protein?
Component of the dammarane-type triterpene saponins (e. g.  PPT-type ginsenosides or panaxosides) biosynthetic pathway (PubMed:27746309, PubMed:29378087).  Catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis, a class of tetracyclic triterpenoid saponins.
What are the official names of this protein?
Protopanaxadiol 6-hydroxylase, P6H, Cytochrome P450 CYP716A53v2, Protopanaxatriol synthase, PgPPTS.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LYAG_PONAB
Sequence: MRVRHPPCSRRLLAICALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHLGRPRAVPTQCDVPPNSRFDCAPDKAITREQCDARGCCYIPAKQGLRGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPRVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRVTLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVRQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITSQVVENMTRAHFPLDVQWNDLDYMDARRDFTFNKDGFRDFPAMVRELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETSQPLIGKVWPGSTAFPDFTNPAALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPDNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNGLLNLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGIWYDLQTVPIEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVLFLARNNTIVNELVHVTSEGAGLQLQKVTVLGVATTPQQVLSNGVPVSNFTYSPDTKVLDIPVSLLMAEQFLISWS
What is the function of this protein?
Essential for the degradation of glycogen in lysosomes.  Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans.
What are the official names of this protein?
Lysosomal alpha-glucosidase, Acid maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Lysosome. Lysosome membrane.
Protein: XDHA_BACSU
Sequence: MGNFHTMLDALLEDQEEAVLATIVQVEGSAYRKAGASMLFKKKGRRIGLLSGGCVEEDVFQRISALGDQLTSTLIPYDMRSEDDLSWGMGAGCNGIIHVHAERITQEKRRHYEKVRDCLHSGKAVTSVIKIESSHYLFLTENGHFGNWPDAPLQDIQRTVSTLHLPHFDQTTNMFIQRIEPKPRLILFGAGPDNVPLANLAADTGFSVIVTDWRPAYCTSSLFPKADQLITAFPEQMLSEFQFFPHDAAVVATHHYQHDQTIINFLFSQNLHYIGLLGSANRTKRLLSGKHPPSHFYSPVGLKIGAEGPEEIAVSVVAEIIQTRKRVAVV
What is the function of this protein?
Oxidizes hypoxanthine and xanthine to uric acid.  PucA subunit could exert a molybdenum cofactor recruiting function.
What are the official names of this protein?
Probable xanthine dehydrogenase subunit A, XDHase subunit A.
Protein: GLND_VIBVU
Sequence: MAFQSPLTFNDEQLTVAQLKSQLDLFANAQKQAFLNHHPVTDLVLSRAEYMDLLLTRLWRYYGFSEIHNISLVAVGGYGRGELHPLSDIDILVLSKHKLPGELETKLSEFITLLWDLRLEVGHAVRTVEECAAIGREDLTVATNLQEARLLCGSENTFQDLKKVVLSDSFWPSETFYRAKIQEQRERHARYHDTTYNLEPDIKSTPGGLRDIHTLSWVARRHFGATSLLEMSRYGFLTDAEYRELVECQDFLWRVRFALHIELKRYDNRLTFAHQIQVAEHLGFKGEGNRGIEMMMKEFYRTLRRVAELNKMLLKLFDQAIINGGETEPAVIINEDFQRRGRLIEARKPALFQARPETILDMFLHIANDSTIDSVSPPTLRQLRTARRRLNKFLHTIPEAREKFMELVRHPNALHRAFSLMHKLGVLAAYLPQWSQIVGQMQFDLFHVYTVDEHSVRLLNHINTFSYAKNHDKHPICCEVYPRLQKKELLLLAAIFHDIGKGRGGDHSEIGEKEAYDFCIEHGLSKPEAKLVSWLVRHHLLMSVTAQRRDIYDPEVITEFAKQVRDEERLEYLVCLTVADICATNPELWNSWKRTLLAELFYSTQRALRRGLENPVDVRERIRHNQQLASALLRKEGFTAREIEVLWQRFKADYFLRHTHKQIAWHCEHILRMDNPEQPLVLMSKKATRGGTEVFVYTKDQHALFATVVAELDRRNFNVHDAQIMSSKDGYVLDTFMVLDQHGQAIDVDNHKAVIKHLMHVLADGRPTKVKTRRTPYKLQHFKVKTKVDFLPTKSKKRTLMELVALDTPGLLAITGATFADMGFNLHGAKITTIGERAEDLFILTSENGGRLSEEQELQLREKLIHNIAELAP
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: GLB1B_ANATR
Sequence: MSTVAELANAVVSNADQKDLLRLSWGVLSVDMEGTGLMLMANLFKTSSAARTKFARLGDVSAGKDNSKLRGHSITLMYALQNFIDALDNVDRLKCVVEKFAVNHINRQISADEFGEIVGPLRQTLKARMGSYFDEDTVSAWASLVAVVQAAL
What are the official names of this protein?
Globin-1 subunit beta, Globin I beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: URE3_HAHCH
Sequence: MELTPREKDKLLLYTAALVAERRKARGLKLNYPEAMAYLSMEIVEGARDGRSVAELMAYGRTLLSRDDVMEGIPEMIPEVQVEATFPDGTKLVTVHNPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_HAEDU
Sequence: MISKIITSIFGSSNDRTLKRLKKRVVHINKLEAEFEKLSDQELQAKTAEFKQRLAEGATLDSLLHEAFATVREASRRVMGMRHFDVQLIGGMVLTNRNIAEMRTGEGKTLTATLPCYLNALMGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVAVNIAGLASEVKREAYNADITYSTNSELGFDYLRDNLAHTKEERFQRELYYALVDEVDSILIDEARTPLIISGPAEDTTQIYQAIDTIIPHLISQDKEDSDEYTGEGDFTLDLKNKQAHLTERGMVKVEGILTEMGLMQEGETLYHPARIALLHHVYAALRAHKLFEVDVDYIVKDGEVVIIDEHTGRTMAGRRWSDGLHQAIEAKEHVNIQGENQTVASITYQNYFRLYEKLAGMTGTADTEAFEFQQIYGLDTVVIPTNKPVIRDDRTDLMFKSEQEKFAAIIKGIEECMSRQQPVLVGTASVEKSELLSNALTKAGIKHNVLNAKFHAQEAEIVAEAGAPSAVTIATNMAGRGTDIVLGGNWKAELAKLDNPTEAEIEAIKSAWKTRYDTVMQAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDTLMRIYLNEGKLNMMRKAFSEEGEAMESKLLTKVIASAQAKVEAHNFEGRKNLLQYDDVANEQRKAIYEQRNYLLETNDISAMIETIRDDVFNHVISRYIPPQSIEEMWDIAGLEEVLHHQFGMELPIQQWLEKEKDLHEETLRERIINLAKQEYQSKEEKVGAEVMRNFEKGVMLQNLDELWKEHLSAMDYLRKGIHLRGYAQKDPKQEYKKESFEMFTNMLELLKSNVISILSRIQVRSQQEIEEAQRQQHEQAEAESANYQATTEEALAKEKRDALPAELTNLQIGRNDPCPCGSGKKYKHCHGSKARYV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GCP5_MOUSE
Sequence: MARPKSSGSRMDRQLEHDVCELVRQVTGLQDEADPNFQLALDFVWSNFRFHRFLDVNSHKVEKTIEGIYEKFTIHSDLNKAASWKRLTKEFLNASLPSTEKIKTDAHYSILSLLLCLSDSPSNSNYVETPREKEVEKKDDFDWGKYLMEGEEIGLGPNIDTPNWSEDSDDEDAQQPLSREDSGIQVDRTPLEEQDHNRKGGPQVCWEDEPDSRSWLEQHVVHQYWTTRRFRIPHSAHLHSNLAAVWDQHLYSSDPLYVPDDRVVVTETQVIRETLWLLSGVKKMFIFQLIDGKVTVRNNIIVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESLPPGNGPIPKKQPDAPFRTYQAFMWALYKYFINFKEELTDIEKCVISSDTTITLAIVVNKLAPRLAQLKVLDKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEDKVSDSASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLNCAEGPACQAAARDAERKSLYTLFLESIQLRLQHGEDSAPHIVNEDQTTKENLIKMQSIAERHLELDDIHDPLLAINFARLYLEQSDFHEKFAGGDICVDRSSESVTCQTFELTLRSCLYPHIDKQYLHCCGNLMQTLKRDFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSLRLSISFENVDTTKKKLPVHILDGLTLSYKVPWPVDIVISVECQKIYNQVFLLLLQIKWAKYSLDVLLFGELGNAAERSQAKEDIPRDQDTPSQFGPPKESLRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALMFAEGWQAGLGAWQMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS
What is the function of this protein?
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
What are the official names of this protein?
Gamma-tubulin complex component 5, GCP-5.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RBFA_PARDP
Sequence: MAQNRFHSGTGPSQRQLRVGELIRRTLSDVLLRGDVHDPELNRHSITVGEVRTSPDLKVATAYVLPLGGHDAEEALAALRRNAGELRHLVAKAMTLKYAPQLRFVLDETFDRMDDTRRLLSEDRVRRDVESHPEDDED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COF_ECO27
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: MOCS3_DROMO
Sequence: MIAATADSFEIEKAKLCRKIAELQAALNAKDQKLRELQLAADNLLAEGEVQLAPRDHYTELSNDDIARYSRQLILTDFGVSGQMKLKNSAVLIVGLGGLGCPAAQYLASAGCGNLGLVDYDEVEPSNLHRQTLHTVSRCGISKAESARIALLELNPHCRIICYSNLLNSFNAMQIIPAYDVILDCSDNVATRYLLNDACSILQKPLVSGSALKMDGQLTVYCYGENGPCYRCIYPVPPPPEAVTNCGDGGVLGAVTGTIGALQAMEAIKVIVGLGEVLAGRMLIFDGSSCQFRNIKIRGKRPNCHVCSSQPLITGLIDYELFCGMNANDKDNALQLLEPEQRINVLDYHKLATEKKSHLLLDVRPPAEFEICQLPDAVNVPLAQILDDSYVQRFAQQLESKEYPIFVVCRRGNDSQIAVQHMKTRFPDHSIRDLEDGMHAWTKLVDQNFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin activating enzyme 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_FRATT
Sequence: MLIYLFEWLSHYFKGLEVFSSYISVRIIMISITSLLITLALGRPMISWLQKMQIGQIVRDDGPQSHFSKRNTPTMGGVLILSSVIISCLLWGDLTSIYLWILILVVIFFGAIGFFDDYLKLVLKHPKGLRAKYKFALQSIFSIVLAIVLFYLLSKNGQMSLSIPFSKSLYIPIGIVIFVVLAFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIETNSTLANYLLFNYLGNPGLAEVAVFCAAVCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMVRQELIFFIMGLLFVVEALSVMLQVGSYKLRNGKRIFRMAPIHHHFELKGWPETKVVIRFWIISLILFLIGLAAIKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HMHA1_MOUSE
Sequence: MFSRKKRELMKTPSISKKNRAGSPNPQSSSGELPRKDWTEAPGLEPPATSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGTATWTLVRGYRSPLSAASPAELPTEGAFPDGVEDISTLLADVARFAEGLEKLKECVLQDDLLEARRPLAHECLGEALRVMRQVISRYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVSEFLLGEVDSSTLLAVPPGDPSQSMENLYGAGTEGPPHNVEECEEGCLPPEEVDMLLQRCEGGVDAALQYAKDMARYMKDLISYLEKRTTLEMEFAKGLQKVVHNCRQSVTHEPHMPLLSIYSLALEQDLEFGHGMVQAAGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQRKLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNNSWSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEAAPNKDHRGGRGHQVHKSWPISISDTEVGLDTSSGDLKKFDRTSSSGTMSSSEELGDQEAGLVASAFDSADLNGMDPELPVAMPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAASRGRQGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVEMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEEAPGSQEGASTQCGQLESAEGIVFPLQEEAEDGSRESHAASNDSDSELEDASDPLSSSDASALHRLSFLEQTEAGLEEGPQSHSGSEEQLEGEDGAPGPWLCHFNTNQSNNTSRAPLPTMRLRGGQITGGTSQERQPQFV
What is the function of this protein?
Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading.  However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity.
What are the official names of this protein?
Rho GTPase-activating protein 45, Minor histocompatibility protein HA-1.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, ruffle membrane.
Protein: KDSB_SHEB8
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPEAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKTELDDPMHVKMVFDNNNYALYFSRSRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQRLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D106A_GORGO
Sequence: MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID
What is the function of this protein?
Has antibacterial activity.  Acts as a ligand for C-C chemokine receptor CCR2.
What are the official names of this protein?
Beta-defensin 106A, Defensin, beta 106, Defensin, beta 106A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: PROD2_BACNA
Sequence: MVITRDFFLFLSKSGFLNKMARNWGSRIAAGKIIGGNDFNSSIPTIRQLNSQGLSVTVDHLGEFVNSAEVARERTEECIQTIATIADQELNSHVSLKMTSLGLDIDMDLVYENMTKILQTAEKHKIMVTIDMEDEVRCQKTLDIFKDFRKKYEHVSTVLQAYLYRTEKDIDDLDSLNPFLRLVKGAYKESEKVAFPEKSDVDENYKKIIRKQLLNGHYTAIATHDDKMIDFTKQLAKEHGIANDKFEFQMLYGMRSQTQLSLVKEGYNMRVFLPYGEDWYGYFMRRLAERPSNIAFAFKGMTKK
What is the function of this protein?
Converts proline to delta-1-pyrroline-5-carboxylate.
What are the official names of this protein?
Proline dehydrogenase 2, PRODH 2, Proline oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the proline dehydrogenase family.
Protein: ATPD_ACTSZ
Sequence: MSELTTIARPYAKAAFDFAVEQSAVEKWHEMLAFIAEVAKDEQIQQFLTSSLSPEKVADTVISICGEHLDKSGQNLIRLMAENKRLTVLPAVFNEFRHYMEEYNAIAEVQVISAQPLNATQTDKIAAAMEKRLARKVKLNCSVDNTLIAGVIIRTDDFVIDGSSRGQLNRLANELQ
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CEBPG_BOVIN
Sequence: MSKVSQQNSTPGVNGISVIHTQAHASGLQQVPQLVPAGPGGGGKAVPPSKQSKKSSPMDRNSDEYRQRRERNNMAVKKSRLKSKQKAQDTLQRVNQLKEENERLEAKIKLLTKELSVLKDLFLEHAHNLADNVQPSSTENTTNPDKAGQ
What is the function of this protein?
Transcription factor that binds to the promoter and the enhancer regions of target genes.  Binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene.  Binds to the promoter and the enhancer of the immunoglobulin heavy chain.  Binds to GPE1, a cis-acting element in the G-CSF gene promoter.
What are the official names of this protein?
CCAAT/enhancer-binding protein gamma, C/EBP gamma.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYY_YERPS
Sequence: MTSSNLIKQLQERGLVAQVTDEDALAERLAQGPISLYCGFDPTADSLHLGHLVPLLCLKRFQLAGHRPVALVGGATGMIGDPSFKASERKLNTEDTVNEWVEKIRHQVSPFLDFDCGENSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDSGISFTEFSYNLLQAYDFACLNKNHGVALQIGGSDQWGNITSGIDLTRRLHQQQVYGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSLEEINALEEEDKNSGKAPRAQYVLAENVTGMVHGPEGLAAAKRITESLFSGDLHDMTEADFAQLAQDGMPTVELNRDADLQQALVNAELVPSRGQARTMIGSNAVAINGEKQADPEYVFTDADRLFGRYTLLRRGKKHYCLISWL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_STAAR
Sequence: MYNGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMDMGKAYEATVSIGRSTTTEDQTGDTLEMKGVHSANFNNDDIDRLLESFKGIIEQIPPMYSSVKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTLATDIGVKLGFPAHMSKLTRIESGGFVLKDSLTLEQIKELHEQDSLQNKLFPLEYGLKGLPSIKIKDSHIKKRILNGQKFNKNEFDNKIKDQIVFIDDDSEKVLAIYMVHPTKESEIKPKKVFN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y232_TREPA
Sequence: MYCTRCVFAGARGGERSPAAVLSVGKIPAPIVISGYLC
What are the official names of this protein?
Uncharacterized protein TP_0232.