PharMolix/UniProtQA huggingface dataset:
Protein: CSST1_CONMA
Sequence: MQTAYWVMVMMMVWITAPLSEGGKLNGEIRGLVSHILIPQHTLRSLTSRDRSDNGGSSGAQICIWKVCPPSPWR
What is the function of this protein?
Moderately activates human somatostatin receptors (SSTR) with a preferential activation of SSTR1 and SSTR4.  In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter.  Four to five hours after injection, mice recover, even with the highest dose tested.  Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system.
What are the official names of this protein?
Consomatin Ma1, ConSST Ma1, Somatostatin-related peptide, SSRP.
What is the protein family that this protein belongs to?
Belongs to the conotoxin C superfamily. Consomatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPB2_CAEEL
Sequence: MYDDEDEMVNDPMDGDYIDDSDEISAEAWQEACWVVISAYFDEKGLVRQQLDSFDEFVQMNVQRIVEDSPPVELQSENQHLGTDMENPAKFSLKFNQIYLSKPTHWEKDGAPMPMMPNEARLRNLTYASPLYVDITKVVTRDDSATEKVYDKVFVGKVPVMLRSSYCMLSNMTDRDLTELNECPLDPGGYFVINGSEKVLIAQEKMATNTVYVFSMKDGKYAFKTECRSCLENSSRPTSTMWVNMLARGGGGGKKTAMGQRIIGILPYIKQEIPIMIVFRALGFVSDRDILGHIIYDFNDPEMMEMVKPSLDEAFVIQEQNVALNFIGARGAKPGVTREQRIKYAREILQKELLPHVGVSEHCETKKAFFIGYMVHRLLLAALGRRELDDRDHIGNKRLDLAGPLLAFLFRSLFRNLLKEMRMTAQKYINKNDDFALDVCVKTSTITRGLTYSLATGNWGDQKKAHQSRAGVSQVLNRLTYTATLSHLRRANSPIGREGKLAKPRQLHNTQWGMVCPAETPEGQAVGLVKNLALMAYISVGSLPEPILEFLEEWSMENLEEVSPSAIADATKIFVNGAWVGIHREPDQLMTTLKKLRRQMDIIVSEVSMVRDIRDREIRIYTDAGRVCRPLLIVENQKLALKKRHIDQLKEAADEANKYTWSDLVGGGVVELIDSMEEETSMIAMMPEDLRSGGYCDTHTHCEIHPAMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYTTNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFNELPAGINAIVAILSYSGYNQEDSVIMNNSAIDRGLFRSVFYRSYRDNEANLDNANEELIEKPTREKCSGMRHSLYDKLDEDGIISPGMRVSGDDVIIGKTVALPDIDDDLDASGKKYPKRDASTFLRSSETGIVDQVMLSLNSDGNKFVKIRMRSVRLPQIGDKFASRHGQKGTMGIMYRQEDMPFTAEGLTPDIIINPHAVPSRMTIGHLIECLQGKLSANKGEIGDATPFNDTVNVQKISGLLCEYGYHLRGNEVMYNGHTGKKLTTQIFFGPTYYQRLKHMVDDKIHSRARGPIQMMNRQPMEGRARDGGLRFGEMERDCQISHGATQFLRERLFEVSDPYHVYVCNNCGLIVVANLRTNSFECKACRNKTQVSAVRIPYACKLLFQELMSMSIAPRLMVKPRQSKRSKHQSEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TLR3_BOVIN
Sequence: MSRPLPYHIHFFSGLLTCWILCTSSAHKCTVRHEVADCSHLKLTQIPDDLPTNITVLNLTHNQLRRLPPANFTRYSQLTTLDGGFNSISKLEPELCQSLPWLEILNLQHNEISQLSDKTFIFCMNLTELHLMSNSIQKIKNDPFKNLKNLIKLDLSHNGLSSTKLGTQLQLENLQELLLSNNKISSLTPGEFDFLGNSSLKRLELSSNQIKEFSPGCFHTLGELSGLSLNNAKLSPSLTEKLCLELSNTSIENLSLSSNQLDTISHTTFDGLKQTNLTTLDLSRNSLRVMGNDSFAWLPHLEYLSLEYNNIEHLSSRSFYGLSNLRRLDLRRSFTRQSISLTSLPKIDDFSFQWLKCLEYLNMDDNNFPGIKRNTFTGLVRLKFLSLSNSFSSLRTLTNETFLSLAGCPLLLLDLTKNKISKIQSGAFSWLGHLEVLDLGLNEIGQELTGQEWRGLDNIVEIYLSYNKYLELTTNSFTSVPSLQRLMLRRVALKNVDCSPSPFRPLPNLVILDLSNNNIANINDELLKGLEKLEILDLQHNNLARLWKHANPGGPVQFLKGLFHLHILNLGSNGFDEIPVEAFKDLRELKSIDLGMNNLNILPQSVFDNQVSLKSLSLQKNLITSVQKTVFGPAFRNLSYLDMRFNPFDCTCESIAWFVNWINITHTNISELSNHYLCNTPPQYHGYPVMLFDVSPCKDSAPFELLFMININILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKEIDRAEQFEYAAYIIHAYKDRDWVWKHSSPMEDEDHTLRFCLEERDFEAGVLELEAIVNSIRRSRKIIFVVTQNLLKDPLCKRFKVHHAVQQAIEQNLDSIILIFLEEIPDYKLNHALCLRRGMFKSHCILNWPVQKERVNAFHHKLKVALGSRNSAH
What is the function of this protein?
Key component of innate and adaptive immunity.  TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms.  TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection.  Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).
What are the official names of this protein?
Toll-like receptor 3.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane. Early endosome.
Protein: RF1_SHEHH
Sequence: MKDSVIRKLEGLLERNEEVLALLSDASIIADQERFRALSKEYSQLEDVVRTFKSYQQAEEDFESAKEMMEEDDPELKEMAQEEYKATKEAIATLEAELQILLLPKDPNDDNNCFIEIRAGAGGDEAAIFAGDLFRMYSRYAESKRWQIEVMNTNEGEHGGFKEVIAKISGEGVYGKLKFESGGHRVQRVPETESQGRVHTSACTVIVLPEVPEAEAIEINKADLKVDTFRASGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLAARIQAVEDEKRRSAEESTRRNLVSSGDRSERIRTYNYPQGRVSEHRINLTLYRLNEFMEGDIDCVVEPLIQENQADMLAALGEA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC124_NPVAC
Sequence: MGLFACCTKYTRLSTDTKMKFPYVALSYINVTLCTYTAMLVGYMVTFNDSSELKYLQYWLLLSFLMSVVLNAPTLWTMLKTTEAHEVIYEMKLFHAMYFSNVLLNYVVFLDNQMGTNFVFVNNLIHCCVLFMIFVELLILLGHTMGTYTDYQYVKSCYMVILFVSVMSVTIVMGLECLKTKLIDNSLMFNAFVCALYIVIAIMWSLKNNLTSYYVSNLQSIQVVPFSYNDPPPPFSNIVMDDIKNKK
What is the function of this protein?
Accelerates mortality in insect larvae.
What are the official names of this protein?
Protein AC124.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Present in the host cytoplasm from 24 hours to 48 hours post infection. At 48 hours, localizes throughout the cytoplasm and the nucleus.
Protein: SYDP_ALISL
Sequence: MPLSVEQALANFSQRYVEAWKEKHDSLPINEELVGLASPCIDETRNLEVLWQPVARDESIRLVNIENGIELDLHDDFHAFYGAQFSADMTAKFEGMNVELLQIWSDEDLENLQGNMLGHLVMQRRLKLVPTLFIAVTDDEMEVISICNQSGEVILDTVGTKKRKVLAESMAEFLEKLEPVVA
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: AAEA_YERPA
Sequence: MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPAEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSADSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL31_SHESA
Sequence: MKPGIHPEYAVITANCTCGNVIKVNSTAGKDLHLDVCGACHPFYTGTQKVVDTGGRIDKFNKRFGMLGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: CXA3_CERLA
Sequence: ISWPSYPGSEGIRSSNCQKKLNCGTKNIATKGVCKAFCLGRKRFWQKCGKNGSGSKGSKVCNAVLAHAVEKAGKGLIAVTDKAVAAIVKLAAGIA
What is the function of this protein?
Permeabilizes a variety of cells.  Forms large pores which allows the release of large proteins almost as rapidly as small organic molecules and inorganic ions.  At sublytic concentrations, the toxin also inhibits protein kinase C and endogenous voltage-gated cation selective (sodium, calcium) channels occurring in the nervous and cardiovascular systems.
What are the official names of this protein?
Cerebratulus toxin A-III, Cytolysin A-III, Cytotoxin A-III.
What is the protein family that this protein belongs to?
Belongs to the worm cytolysin family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_PSET1
Sequence: MKFVDEVEIRVEAGDGGAGIVSFRREKYIPEGGPDGGDGGDGGSVYLQADENLNTLIDYQFERFHRADRGTNGRSRNCTGKKSDDLIIMVPVGTRIMDVDTQEGLGDLTQHGQKILVAKGGFHGLGNARFKSSTNRAPRQKTLGTEGEVRNLKLELLLLADVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLIPNLGVVRPEANKSFVIADIPGLIEGASDGAGLGIQFLKHLERCRILLHIIDVMPVDGSNPVDNAFAIVNELHQYSPKLAEKPRWLVFNKIDLLPADEAKALCEKIAQELGETENIYSISAINKSNTQPLIHDVMTLLESMPKEKFVETTDEEVEFKWDTYHQKAAKKSDDDDDWDEWNEDDYDVEVVYER
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_RHOPT
Sequence: MTPSAASALVEKTPLETYVPPAKPSLIGLSRAQLCDRLGDVGVAPPQRKMRAQQLWHWMYVRGARDFSEMTNVSKEMRATLAEHFTVDRPEVVAEQISADGTRKWLLRLPSGGDGQKAHEVECVYIPETDRGTLCVSSQVGCTLNCAFCHTGTQRLVRNLTAGEIVGQVMVARDRLGDWIDRETPNGNRLITNIVMMGMGEPLYNFDAVRDALLIVSDNEGIGISRRRITLSTSGVVPNIKRTGDEIGVMLAISLHAVRDELRDELVPLNRKYPLKELLQACRDYPGASNARRITFEYVMLKGVNDSLDDARKLVQLLKGIPAKINLIPFNPWPGSNYECSDWDQIEKFSEYVFNAGYSSPVRTPRGRDILAACGQLKSETEKLSVRERNALRAMAMTD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLE_SORBI
Sequence: MHDEEKKEPKWVTAVSIAGRIAGMGLAVAAAVLMSTASQCTVYYAAPAASAYGGAARARTVTYSDFPPFVFLVGAASIAAFLEAIAIFLVVWKKGKDKTTKVLMPLLGVAVPALLYSATGAAFAAVSDMSYCSANGKRVSICAGSAAAGGGVSGGTNFCSQVHIAVYLSLAAAVAVSVAEVVRGLGGSASGGGSDSDSSSSSESGGCDHGCHHKH
What are the official names of this protein?
CASP-like protein 1U3, SbCASPL1U3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURG_ALKEH
Sequence: MTMPVLIMAGGTGGHVFPALAVAERLREQGVPVVWLGTREGLEARVVPAADIPLESLRVRGLRGNGLRGWLAAPFVLLRALWQALGVLRRHRPRAVLGMGGYAAGPGAVAAWLTRRPLIIHEQNAVAGLTNRLLSRLARRVLTGFPGILPERGGEHVGNPVRDAITRVPGPADRGAGAHEPLRLLVVGGSLGALALNSTVPAALARLPEVQRPVVRHQAGERTLQQAREAYDQAGIAVDLQPFIEDMAAAWTWADLAICRAGALTVAELEAVGVPAILVPLPGAVDDHQTANARQFVAAGAGVLLPQSELSAQRLALELKTLLADPPRLQRMAQCARGLGRPDAAATVARICLEEAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHEB4_BURTA
Sequence: MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQAVDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVTANVGANASYVYEAMGAGALDAVDTPTLGQGGSADPSQPLLAKIDQIGRLLATRMPAAAPAAAAPAPQGALPPLVAIGASAGGPTALTALLRRLPEDFPAAIVIVQHVDQAFAIGMAQWLDGYSRLPVRIARQGGVPQAGEVLLAATNDHLHLTARGSLAYTRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAVLPLERIADQLISLVQRNRQRRR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 4.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG1_VIBVY
Sequence: MARKTPIERYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWRGMEAQFQDHRVNIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQADKYHVPRMVFVNKMDRAGADFLRVVDQIKNRLGANPVPIQLNVGAEEDFKGVIDLIKMKMINWNEADQGMTFTYEEIPADMIELAEEWRNNLVEAAAEASEELMDKYLEEGELTEAEIKQALRARTLNNEIVLATCGSAFKNKGVQAVLDAVIEYLPSPIDVPAIKGIDENDNEVERHADDNEPFSALAFKIATDPFVGTLTFIRVYSGVVNTGDAVYNSVKQKKERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCNSDHKVILERMEFPEPVIQIAVEPRSKADQEKMGIALGKLAAEDPSFRVETDAETGQTLISGMGELHLDIIVDRMKREFSVDCNVGKPQVAYRETIRGKSEVEGKFVRQSGGRGQYGHVWIKLEPSEPGAGFVFVDEVVGGVIPKEYISSVAKGIEEQMNSGVLAGYPVLDIKATLFDGSYHDVDSSEMAFKIAGSMAFKKGALEAQPVILEPMMKVEVTTPEDWMGDVVGDLNRRRGIIEGMDEGVAGLKIIRAQVPLSEMFGYATDLRSATQGRASYSMEFFEYAEVPKNIAEAIVAERGY
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PODJ_CAUVN
Sequence: MTAASPWSVKGIDPKAREVAKDLARRSGMTLGEWLNRMIIEGDGQTADPRLAGDDVPNRAYLEIVKDDAPPRIEIAEHPADEVGRVALALDRLTQRIEAAEGRNAAAITGIDHSVRDALTRLGASEREQIAVAARFEGAVDELKTEQARATERLRRIESEAAGPRSAEALRALEGALGKVAGHLYEGEARTREAIATLEAKLNQQSSGDPSALVEAVVARLGERLEAAETRTSDALRELGASFQALDQRLGAVETANPATGVQEGLDSLAATLTQKMEAARLEMAAKLRESADGRFDRMERKLGEMAAHVQAAEQRSAQAIERMGREIVGVADAFNRRVHAAESRNASAIEQVGGEVARIAASVEHKLNRADSVQAQALEKLGGEIARITEKLAERIGSAERRNALAIDDVGEQVARVTERLNQRHERSSQELVDRIRQSEERTLRMLEEAREKIDSRLSEAQRKLEAAPPSPPPAQAPAPVATAQRPVPPAASPFEDNYFSQAASFSTSEDEADAFDAPPAPARSFEVAEFPAAEPEEPAFAHDDYAIADGFEPESPRYEVEPEVSDFAPAEPSRPMSTRDIIEQARAAARAAAASEGKGGKAKSAKKEKASKASGSLFSGFGGFSTKKSKARLGATVTTALVVFAAAGALGAGVGGLLLLNTDDGNNSPSRVAQAIAGRKADVEVNGPEADTTPGAPRAAVALTTGKVVPAEVEAPAAPPTNEAKALFEDAVRKIESGDRSGVELLKRAANGGYPAAQFYLSKMYEGGKNGVKVDMAEARRWSERAANGGDPRAMHNLALYYFKGEGGPRNSTTAASWFRKAADMGLVDSQFNLAQLYESGLGVSQNPAEAYKWYVIAGRAGDSTARGRATALRSQLTAEAQQTADRSALAFRPQTQVQTASLSSAAPAAANANLGVAQRVLSQLGYYQGPRDGVSSPALRMAIAAYQRDQGLPPTGSVDAETLNRLSVYAR
What is the function of this protein?
PodJL provides the positional information for the localization of several polar organelles (pili, adhesive holdfast and chemotactic apparatus) by recruiting structural (CpaE) and regulatory (PleC) proteins to a specific cell pole.
What are the official names of this protein?
Localization factor PodJL, Polar organelle development protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Both PodJL and PodJS localize to the swarmer pole at different stages of the cell division.
Protein: CD4_SHEEP
Sequence: KAVVLGKAGGTAELPCQASQ
What is the function of this protein?
Accessory protein for MHC class-II antigen/T-cell receptor interaction.  May regulate T-cell activation.
What are the official names of this protein?
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UL95_HHV7J
Sequence: MDTDIALAAIYKETTKLNEKDAKIFSEAVQTALTVCKATAPNTRLKLVETPTNNFLLVTNVVPSETSKATTEANLNIDAALEKLASSFNTAVPVKSSKKYLLQNVRKMTSENIALTGSYIIYTKKHIEVAFLLDKSDFVQDILRYAETPSLLGHTDVRDLECLLWLAFCGPMSYCQADNCFGLNKAGYNAPFPILFPPCMYERNMNLSVFFGLLQIYVFSLYRDFSVENSNLQQGIKKRIKLVLSDLRAKERICEEEIGNFPLAAQICLFCALYRQNRLCMEYAANNLSMSVFSPIILKDCTFMQTTVTITQILPGSKEAIIFPVYDIGKLLSALVFSENGVLLKL
What are the official names of this protein?
Protein U67.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL95 family.
Protein: TR150_RAT
Sequence: MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDIKGSESSKPWPDATTYGTGSASRASVSDLSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSNASQMGSSMSGGAGYQSGAHQGPFDHGSGSLSPSKKSPVGKSPPATGSAYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKLKEKGGFSDADVKMKSDPFAPKTDTEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDEQDKDKCKGRKEPEFDDEPKFISKVIAGASKNQEEEKSGKWESLHAGKEKQRKAEELEEEPFTERSRKEERGGSKRSESGHRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGNKGDFSSGKSSFSITREAQVNVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELFAQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGNEQEAAKTKKSPEIHRRIDISPSTFRKHGLTHEELKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDSRDSSHSRERSTEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYPEEAEDREESTTGFDKSRLGTKDFVGPNERGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDFQKRSREEEWDPEYTPKSKKYYLHDDREGEGSDKWMSRGRGRGAFPRGRGRFMFRKSSTSPKWAHDKFSGEEGEIEDDESGTENREEKDSLQPSAE
What is the function of this protein?
Involved in pre-mRNA splicing.  Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC).  Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition.  May be involved in nuclear mRNA decay.  Involved in regulation of signal-induced alternative splicing.  During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells.  Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.  Involved in response to DNA damage.  Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex.  Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit.  Cooperatively with HELZ2, enhances the transcriptional activation mediated by PPARG, maybe through the stabilization of the PPARG binding to DNA in presence of ligand.  May play a role in the terminal stage of adipocyte differentiation.  Plays a role in the positive regulation of the circadian clock.  Acts as a coactivator of the CLOCK-BMAL1 heterodimer and promotes its transcriptional activator activity and binding to circadian target genes.
What are the official names of this protein?
Thyroid hormone receptor-associated protein 3, Thyroid hormone receptor-associated protein complex 150 kDa component, Trap150.
What is the protein family that this protein belongs to?
Belongs to the BCLAF1/THRAP3 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus speckle.
Protein: AMPA_SINMW
Sequence: MPTKFEFSFSKSHRPAGGVAVLLQAAGAKEAAGAAVADPESVLAKAAKIGKFTGKALSTLDVIAPHGSPADRIVLLGVGHAAGMGDHDWLKAGGAAAAKLRSAEKITVFLDAPGIEVTGKAAADFALGMEMNAYSFESYKTRKSDDEPKTTQKPVKVTIVTATVIAAKKAFGTAQAVGEGVFLARDLVNEPANVLGPVEFAARAKELEKLGVEVEILTEREMKKLGMGALLGVAQGSSRPPRLVVMQWKGGKAKDKSVAFIGKGVVFDTGGISIKPASGMEDMKGDMGGAAAVTGLMHVLAARKAAVNAIGIIGLVENMPDGSAQRPGDIVTSMSGQTIEVINTDAEGRLVLGDALWYCNDRFKPQLMIDLATLTGAIMVALSNHYAGLFSNDDRLAEQLLAAGLVTQERLWRMPLGKEYDKMIDSKFADMKNTGGRHGGSVTAAQFLKRFVKDTPWAHLDIAGTAMGSPTDELNQSWGSGFGVRLLDQLVRANYES
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_SALPB
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGIGGMSTKLQAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAGEITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y208_STRP3
Sequence: MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKSTLSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMRAAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHVMMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES
What are the official names of this protein?
Probable ABC transporter ATP-binding protein SpyM3_0208.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ycf16 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TACHY_APIME
Sequence: MIIHSIFLLMVSITLVIAEESDNVLFDKRAPTGHQEMQGKQNSASLNSENFGIFKRALMGFQGVRGKKNSIINDVKNELFPEDINKRAPMGFQGMRGKKASFDDEYYKRAPMGFQGMRGKKSLEEILDEIKKKTTRFQDSRSKDVYLIDYPEDYGKRVLSMDGYQNILDKKDELLGEWEKRAPMGFYGTRGKKIILDALEELDKRGVMDFQIGLQRKKDTTFDDYLDYAINPFDYEKRSTDFQDVESGSESFKRARMGFHGMRGKRDAAGIYGSNSSTVGTIFGYQDMRNRGNNFPVYQVEKRSPFRYLGARGKKNPRWEFRGKFVGVRGKKSSLQTVF
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.  Associated with sex-specific or age/division of labor-selective behavior and/or physiology of honeybees.
What are the official names of this protein?
Tachykinins, AmTRP, Tachykinin-related peptide.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.