PharMolix/UniProtQA huggingface dataset:
Protein: DEF1_PETHY
Sequence: MARSICFFAVAILALMLFAAYDAEAATCKAECPTWDSVCINKKPCVACCKKAKFSDGHCSKILRRCLCTKECVFEKTEATQTETFTKDVNTLAEALLEADMMV
What is the function of this protein?
Plant defense peptide with antifungal activity against F. oxysporum and B. cinerea.
What are the official names of this protein?
Floral defensin-like protein 1, PhD1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted. Vacuole.
Protein: CH10_STRPS
Sequence: MLKPLGGRVALKIEEKGPTVGGFVLAGSAQEKTQTAQVVATGQGVCTLNGDLVAPSVKTGDRVLVEAHAGFDVKDGDEKYIIVGEANILAIIEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_STRPD
Sequence: MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIIEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TES_COLGU
Sequence: MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: TCAF2_BOVIN
Sequence: MATTPAAAFEALMDGVTSWELPEGPVPSELLLTGEAAFPVMVNDKGQVLIAASFYGRGRLVVVSHEGYLLDAGLARFLLNAVRWLSPSPGAPVGVHPSLASLAHILEGSGVEAQVHPEPAEPLGVYCISAYNDTMTAELIQFVKRGGGLLIGGQAWHWASQHGSDQVLSEFPGNQVTSVAGVYFTDTYGVKGRFKVSKKVPKIPLQVRCGEDLRQDQQQLLEGISELDIGTKGLPSQLLVHGALAFPLGLDASLRCFLAAARYGRGRVVLAAHEGMLSAPSLGPFLLNAVRWLAKGQTGKVGVNTSLEKLHTLLLEHGLECSLEPHLTSGVCVYCCTAYSDKEAKQLQEFVAEGGGLLIGGHAWWWASQNPGRSALADFPGNVILNSFGLSILPWTLDPGCFPVPSADSLNYHFRKALSEFQATLNLEGGNLEKNWLAKLRVDGAAFLQIPAEGVPAYASLHRLLRKQLRLRLSGFPAVSRENPVAGDSCEAVVLCLATELARSGTDCSELAQGLGAWSCSSNLCPSEHTVEINARNPSDDAWMSTGLNLPNGQLTEVCLCEAAACAGLKLQIGCHTDNLMSASKLSRAPVVTHQCHMDRTEQLVSNLWGGLLYVIVPTGCNLGPMSITIKRAVPAPYYKLGETSLEAWRSCIQESPAPWGELATDNIILTVPTADLRALEDPEPLLRLWDEMMEAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVSELIDETGMRSRGLWGPVHELGHNQQREQWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPPERENRIKTHLEKGAPLCDWKVWTALETYLQLQEAFGWEPFTQLFAEYQTLSDIPNDNPGKMNLWVRKFSEKVQKNLAPFFEAWGWPVEKEVASSLACLPEWEENPMRMYI
What is the function of this protein?
Negatively regulates the plasma membrane cation channel TRPM8 activity.  Involved in the recruitment of TRPM8 to the cell surface.  Promotes prostate cancer cell migration stimulation in a TRPM8-dependent manner.
What are the official names of this protein?
TRPM8 channel-associated factor 2, TRP channel-associated factor 2.
What is the protein family that this protein belongs to?
Belongs to the TCAF family.
What are the subcellular locations of this protein?
Cell membrane. Note=Colocalizes with TRPM8 on the plasma membrane.
Protein: NTPTH_THEP1
Sequence: MKILITGRPGVGKTTLIKKLSCLLQNAGGFYTEEIRESGKRIGFKIVTLDGEEGILARTDLPFPYRVGKYYVNLKDLEEIGVRSLEGALREKNLIIVDEIGKMELLSSKFREVVEKIFDSEKDVIATIKKSSDPFVERIKSRDGVVVFELNEKNRDSLLKEILYVLKFNRGENNDTGAD
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency.
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: PRIO_MACNE
Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: F185A_HUMAN
Sequence: MLAPCSGWELGCFRLCLRQVRLWAGAGRWACWACQARPYSSGGSERWPGSETEVPPPGPGRRTLKEWTLQVSPFGRLRARLPCHLAVRPLDPLTYPDGDRVLVAVCGVEGGVRGLDGLQVKYDEDLEEMAIVSDTIHPQASVEVNAPLKFGLDIKSSGSGCVKVQSIEGDNCKIETEHGTSILQSVKGQKLHVQTKGGKVICLGTVYGNIDIHASDKSAVTIDKLQGSSVTVSTEDGLLKAKYLYTESSFLSSAAGDITLGSVHGNITLQSKMGNITVDSSSGCLKASTNQGAIDVYVSQLGKVELKSHKGSIIVKVPSSLQAHLQLSGKEVDVNSEVHVQEMAEVRKDDVVTVTGLMNQASKREKWIKADAPKGTVSFRRQSWFQSLKLQD
What are the official names of this protein?
Protein FAM185A.
Protein: LYTN_STAAR
Sequence: MFIYYCKECFVMNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEAVVKTSDTSLKLDNKSAISNGNEINQDMKISNTPKNSNQGNNLVVNNNEPTKEIKIANLEAQNSNQKKVNKGTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKPKTVPSNNKSNSNNSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
What is the function of this protein?
Probably involved in peptidoglycan hydrolysis.
What are the official names of this protein?
Probable cell wall hydrolase LytN.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_LACLA
Sequence: MNKFAIVLAAGKGTRMKSALPKVLHQVAGKSMLAHVLTSVSEVEIAKNVVIVGHEADRVIATLPKGTQFVKQVEQLGTGHAVRIAADLLANEDGATLVIAGDTPLITGQTLEALFDYHFAQNATATILTAIAPNPTGYGRIIRDENGSVEKIVEQKDANDFEKSITEINTGTYIFDNKSLFKALNEITTDNAQGEYYLTDVIEIFKKAGQTVAAHILDDFDESLGVNDRVALSQAELTMRKRINHQHMVNGVTLIDPATTYIDSEVTIGEETVIEANVTIKGNTFIGKNVLITNGSRIENSEIHSNCEVRNSTVEESRMSVGSNVGPYAHLRPGTVLSEEVHVGNFVEIKGSTLGKGTKAGHLTYIGNATVGEKVNFGAGTITANFDGKNKFNTEIDDFAFIGSNSTIIAPLHIGKNALTAAGSVVTEDVPDEAVEIGRGKQVNKLGRAKKMPHYRGQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXPH5_MOUSE
Sequence: MTKVPQGFDFSFLNEEEARKILQVLERNEELRRAEKDRISKLQKTKRDIRWLQGATGEWFEEIQRKKFCNETDVNQMLKPPLTYRLQKGMAKNDPMELQTPRSKSLINQKPSVSSRMSFRSSFASLFSFRRPAKETLKLQSPRPNRCDERVRPSASVRGTASAKIYNSPVGNQPVASVFVPKPAIMREESGMPPPWDASLLESEFFQVLDDLDNKLAQEQSSGLMNTRVPFNYGSRTQFKLSHRNSHGHSTGRQQNYHSETSNMSIYNILRPGTPREGFKTFSPRTKTIYDMYRTREPRVLKEDFMQKNAFGSASLCFDSRQRSASPATGSFTARSLHFPADTQNKSSFTPVRHQQSPKRTPLSSIIWNRSDASRHRQNQEESLGVQAPMDIDPEEQYVSPRCFQESRRYEMCHSQNAYQSYPLNVPVANAMSPDTLENSENMPFYRQSNPFARSFFSSTFRQSREQRFGQNSFWSRQEEYSSWSDFPQSRGPFPSSDKDFEMFSVEANRAPSVCSQGVPSQHWRSHSSGHGTYVFRGREDSHCWRSDFQTSPLESMDTSHVNENQHPPHFVTPVGFSITDSSCHLQSSRLDSQQGYFPVEEAVDEDPYLCGKAQTPASSFRTPFPLSPDDGRESQSSSFPDSTATLQKIIPNKPDFLPIRNCTEVPVACSHSTDSLSLTDTQPNIPVTETNSEKDMDVSVSKDEQLNKTGQKSRPTGLPQYVLHTVISNDLPDFQNAHSRDSAQNDRYGFNAPATERSRRSPRVFSRKGTSQIHTTQRDQSNKLSKNKCFGGDRTLDSAASPPFIQESGTATSLPSPNQGCHQKTGSNEESSNTIKNSHWCFESTANQKSQPSREPALLDLEQSLSTHSTNDSKLAPGHSISRAPLHVASDAPQESFLDARLVPSTTVFSRSLSDQDPGQEQREEKDKATKSQDNQLAVNSTDNQESHDSPALPHDAVHCHPYSPFKNGRGKGRVRRRVSCIEKLTKTERAAAPTREGSGCAEDQRSIKDPELSTVYCTLPRKPASFLIHSRQQESKGTVASVRNGPLPFQIKNKAEVPTGKSTSDKPSSPESVSDAANAVSGTPKATKKMTDMKAIRSASVRKGPLPFLIKRAISCPSGEPCSLAESDDRQKSSVLGMDASPVIPRPGGRIFNSLEGEPSFRESAFSEKELAQEHTGKDRELRAPRMGLFNPSKKTPERLCATGSGKESGRALHKFKTTSMFSVSGDEENVNCLEVVSIYYTLPRKPSKKFCSLLQQYTQGTDSLRDAFQGETEALPNALEIDELNCPAQVQSGIPPPQDPKMQVDSAPCCLSHSPESKDVSQLPDRETSKSTLEEMTSVGPDVSLHREEPTTKEISPSNVSKTAIDDSLSREKREKELLRQILRAPLLHQEKGAGKEHTKSHQQPSKGGNSGPSGLPSRSEDNDENSQTRRDSGTCAGGMASGNGQYPWRDHMAAVVGDRSSRSQPRETSGTTGSDCQNPTDKMLSDSESQAFALTPALCKLQLAEEAQPGGAGLQSEASQAGSQETNTAEMRKVEDEEHMLTRDQTLLPRGNNKNKTNTDETKDRYSGKHRLAAISKASKRIPAKDLSPRKHVATIFSQSESESGFRRLSLYRPEDNPLSPEPTVKATESTDESSQMNVDKSETLLQETTVSSPGPPGQPCHQKSASILQPHLNGSPGVLETPPKSEGSKTQISGELGAPAQLTLTSPLEKGAGHQQRLSPPFPLEPTQKSTINSHCQLRHRSAPSPESEPEPHLYRSKSLKNFNVQSDLLCASHPPKARGRHFSENTSIDNALSQLSLEDGSFPNSGYNRRFKSSSELPASYESESWTSYSNRTRGPKSTSSISRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDVLNASNLSQSELVNSPAGQAPEDGVFPSEPLNIYKDDPVEPLVSDWDTDTTTDDEYYLDEKDKESEL
What is the function of this protein?
May act as Rab effector protein and play a role in vesicle trafficking.
What are the official names of this protein?
Exophilin-5, Synaptotagmin-like protein homolog lacking C2 domains b, SlaC2-b, Slp homolog lacking C2 domains b.
Protein: ARGD_CANGA
Sequence: MYKRYFSTSLKTNQQALKKILEEKTYQVTTYARPSDLCITRGLNAKLFDDFNNKEYIDFTAGIAVTALGHANPKVAEILQTQATKLVHSSNLYFTKECLDLSEKLIEKTKKFGGQHDASKVFLCNSGTEANEAALKFAKKHGITKNPKKQGIIAFENSFHGRTMGALSVTWNKKYRTPFGDLVPHVSFLNINDELSKIKDFINTKKDEIAGLIIEPIQGEGGIFPIPIEKLVALKEICQKNDIIVIYDEIQCGLGRTGNLWAHAALPKAAHPDIFTSAKALGNGFPIAATVVNEKVNNALQVGDHGTTYGGNPLGCAVSNYVLDVIGDQAFLDSVTKKGELLKKGLLKIKEQHPDKISDVRGSGLIWGVEFKDAPGAIVQKARELGLLVITAGKTTVRFVPSLTIEDEVVEEGLTIFNKAVNDVFSK
What are the official names of this protein?
Acetylornithine aminotransferase, mitochondrial, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IDI_CITFR
Sequence: MRQERVILLNEQGQPCGTLEKYAAHTATTPLHSAFSCWIFNEQGQLLVTRRSLHKKAWPGVWTNSVCGHPQLGETTEAAINRRACFELGADIDSLSPVYTDFRYCATDPSGIVENEVCPVYAAHIVSELQLNPDEVMDSQWSNLEDVLSGIDATPWAFSPWMVMQVSDVKARELLRKFANGN
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_MYCTU
Sequence: MTDIGAPVTVQVAVDPPYPVVIGTGLLDELEDLLADRHKVAVVHQPGLAETAEEIRKRLAGKGVDAHRIEIPDAEAGKDLPVVGFIWEVLGRIGIGRKDALVSLGGGAATDVAGFAAATWLRGVSIVHLPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPLAVLVDLATLQTLPRDEMICGMAEVVKAGFIADPVILDLIEADPQAALDPAGDVLPELIRRAITVKAEVVAADEKESELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELARLAGRLDDATAQRHRTILSSLGLPVSYDPDALPQLLEIMAGDKKTRAGVLRFVVLDGLAKPGRMVGPDPGLLVTAYAGVCAP
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEF5_NPVOP
Sequence: MALVKGVAQSQTRPLAFHGEQWTPRALFTVFGAFRASKDYAKLIEFLTNNFACYVKNKTFNFAGTGHLFHSLYAFVPNVSELVKERKQIRLQIDCVMRLFKNTTNDFKMYVELFAFIDAHGGAECPCLLLQQSKLNAVSFVENLNCKLFDIKPPKFKKEPFDSILSKYSLNYKALCFKKKEKCTVGCVTKRQKKMKRRQLLSDRVIYLHNKNDVLDERTLLHGPSGTSLAPCLHRYATVERQTRAGDEMVSFIRYCELCQMRA
What is the function of this protein?
Required for late and very late gene expression.
What are the official names of this protein?
Late expression factor 5.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-5 family.
Protein: PSBP_EUGGR
Sequence: AYGEGANVFGKRKETDQFFEISGDGWSGKL
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: SELD_ACTP2
Sequence: MAEEPIRLTQYSHGAGUGCKISPKVLGTILQSQLDKFIDPNLLVGNETADDAAVYDIGNGIGIISTTDFFMPIVDDPFDFGRIAAANALSDVFAMGGKPIMAIAILGFPVNKLPAEVAQKIVEGGRFACQQAGIALAGGHSIDSPEPIFGLAVTGTVSTEQVKKNASAQAGCELFLTKPLGIGVLTTAEKKGLLKVEHQNLARDVMCQINLIGAQFSQLADVTAMTDVTGFGLLGHLSEICQGSNVRAEVNSAEIHTLDGVKDYIAQGAVPGGTNRNFDSYGHLISAMSDEQKAILCDPQTSGGLLIAVRPQAVEKVQQIAKQANIPLFRVGRLLEADTMKPLIEVI
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: CCL2_MACMU
Sequence: MKVSAALLCLLLIAATFSPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQIQTPKP
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_FRATW
Sequence: MKNEKIVVLYGGDSPEREVSLKSGKAVLDSLISQGYDAVGVDASGKELVAKLLELKPDKCFVALHGEDGENGRVSALLEMLEIKHTSSSMKSSVITMDKMISKEILMHYRMPTPMAKFLTDKLVAEDEISFPVAVKPSSGGSSIATFKVKSIQELKHAYEEASKYGEVMIEQWVTGKEITVAIVNDEVYSSVWIEPQNEFYDYESKYSGKSIYHSPSGLCEQKELEVRQLAKKAYDLLGCSGHARVDFIYDDRGNFYIMEINSSPGMTDNSLSPKSAAAEGVDFDSFVKRIIEQAQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA_CENSY
Sequence: MAFSAKTSGSDDLKAIISAISTLVEEATFVATAEGITFRGMDPSHVALIDISWPNSAFEKYECDSNIKFGVRIDEFTKLIKRADKKDSITISVSKDSMLLIDIGSNKKYKIRLIESSATDTPLPKISYDAKIELATTSFEKILGDVQVVSDYLTIKAKPTGVEFAGKGDSGEAAIDVKKDDDSMEALKVKKESEGTYSLEYLNPIVRAVGGAAGSVTCEFSDAKPLRVEFKVANIGRIHFYLAPRVSS
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: CH60_PORPU
Sequence: MSKQILYQDDARKALEKGMDILTEAVSVTLGPKGRNVVLEKKFGAPQIVNDGVTIAKEISLEDHIENTGVALIRQAASKTNDVAGDGTTTATVLASAIVKQGMRNVAAGSNPMAIKKGIEKATNFVVSKIAEYAKPVEDTTAIVQVASISSGNDAEVGKMIADAIDRVGREGVISLEEGKSTSTSLEITEGMQFEKGFISPYFVTDLDRMEVLQENPFILFTDKKITLVQQELVPLLEQIAKTSKPLLIIAEDIEKEALATIVVNKLRGILNVVAVRAPGFGDRRKSLLEDMSILTGGQVITEDAGFSLDTVQLDMLGKARRVVVTKDSTTIIADGHEATVKSRCEQIKRQIETSDSLYEREKLQERLAKLSGGVAVIKVGAATETEMKDKKLRLEDAINATKAAIEEGIVPGGGSTNVHISGELFVWAKNNLFEDELIGALIVQRALTYPLRRIAFNAGDNGAVVVEKVKTNDFCIGYDASNGKIVNMYDAGIIDPAKVARSALQNATSIAAMVLTTECIVVDKLEA
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, chloroplastic, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TOTB_DROME
Sequence: MNFKTSLICFALLLIGTLCSAYSNQERQRDSRRVAEIMRTSWDDNTKIKRIQELLTIYNRMAPSLRPDERARMDRFISGYTGEIMVDGVPSQGGARRIFKKILSPAAKSVATGFFTELGASLASILTSWFPANTERNH
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot B.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
Protein: ACKA_CORGB
Sequence: MALALVLNSGSSSIKFQLVNPENSAIDEPYVSGLVEQIGEPNGRIVLKVEGEKYTLETPIADHSEGLNLAFDLMDQHNCGPSQLEITAVGHRVVHGGILFSAPELITDEIVEMIRDLIPLAPLHNPANVDGIDVARKILPDVPHVAVFDTGFFHSLPPAAALYAINKDVAAEHGIRRYGFHGTSHEFVSKRVVEILEKPTEEINTITFHLGNGASMAAVQGGRAVDTSMGMTPLAGLVMGTRSGDIDPGIVFHLSRTAGMSIDEIDNLLNKKSGVKGLSGVNDFRELREMIDNNDQDAWSAYNIYIHQLRRYLGSYMVALGRVDTIVFTAGVGENAQFVREDALAGLEMYGIEIDPERNALPNDGPRLISTDASQVKVFVIPTNEELAIARYAVKFA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC8F_SCHPO
Sequence: MNEDETSILNKKMEKIEVEMAEFERLGAEREKEAVERIVQEENQNPEVPSNDDASTDIKSRKEGNMKVTAEEIGLETENFDELPVSNGFGVSRRETHYGNNRTYYKNSQGYRRKPKRDDYNNNRKNFYPPIQNSTYFINATGGIDSMPYFGLNNAPGNIYPFSMYKPLEADPQYLSVPSSMPSRREAGMAYGYQNYKRGGYTPNTQYFEEPLNNTSFPNSQGKEGKNSGYRKSSRILDIRVKFGNSSMKAINFQPKKKIVHVVHNPRLHQNKVLRVSIPGSQPALVTPKHKMNVPPMGMYPLPFSPLPSAAPPIPFSPNVSSHPHMAFLPATVPTHSAPPGFVPYDFPITNDKMYPSPSFQEEFPSTSKSPSATPGSSNAPVVDMHPSADSATYPTSIYPSNVRARDDSQQAYISANMTTGEMPSMTNVPAGNAPAAPGTMYTTPLPTANSPIAYQSYSVMPTYWSFPQNYDSTVPAVYPYMPPPFSGSDMNVMSNPAADTLRSYSPASQVSTPPFGFVYYYDPNQYYVPVSNESANATSQPLSNLDTGGSAPYDHI
What are the official names of this protein?
Uncharacterized protein C622.15c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RAPA_AERS4
Sequence: MPFALGQRWISDTETDLGLGTVVAVEGRMVTLLFPATGENRMYAKEEAPVTRVSFNVGDQIATHEDWTMTVEEVQEKNGLLIYVGVRTDNDEPVALKEVFLSNFIKFNKPQDRLFAGQIDRMSRFTLRYEALINQHKRRLNPTRGLAGGRVSLIPHQLYIAHEVGHRYAPRVLLADEVGLGKTIEAGMIIHQQLLSGRAHRVLILLPETLQHQWLVEMLRRFNLHFSLFDEERCIEAFADAENPFETEQLVICSLDFLRKKRRRFEQVLEAEWDLLVVDEAHHLEWSIDAPSRAYEMVEALAEQVPGVLLLTATPDQLGHQSHFARLRLLDPERFYDYEAFLAEEQAYGKVASAAQELLDGETLSDEARQILASQLEGLDMSDAAARQQAVAKLLDQHGTGRVLFRNSRANIQGFPERHLNVYPMPLPEQYKTAIKVMGMMGGNGGDLQTRALRYLYPEKIFQQFEGENATWTQFDPRVDWLLELLLSARQQKVLVICSEAATAIALEEALRTREGIRGTVFHEGMSILERDKASAYFAQEDGGAQVLLCSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQQNTVEIHVPYLEGTAQRALQLWYHDGLDAFEQTCPTARPVFEAVRDELFELLAANTGDQVTLDALLIKTRELHEPLKARLEQGRDRLLEIHSSGGAAAQLLVDKLAAEDDDTGMVSFALKMFDEIGVNQDDRGENALVLTPGDHMLVSSFPGLPQDGMTITFDRPTALSRDDMALLSWDHPMMRGGIDLILGSEIGATSVALLKNKALPIGSILLELIFVAESAAHPQLYRFMPPTPIRLLMDKNGQNLGEKVAFDAFNRQLTPVNRHLGSKLVTASQPVIHGLIGKGQVIAEELKAGIVDKARTRMAQTLQQDLDRLEALKAVNPNVRDSELDYLRNLQAELHHLIDQTQLKLDAIRFIVVTHN
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: PGM2L_PONAB
Sequence: MAENTEGDLNSNLLHAPYHTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFSRYVPTPFVPYAVQKLKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWNGSWNDNLVDTSPLKRDPLQDICRRYMEDLKKICFYRELNSKTTLKFVHTSFHGVGHDYVQLAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARVVLATDPDADRLAAAELQENGCWKVFTGNELAALFGWWMFDCWKKNKSRNADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIIDLLENGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMASYLETMNITLKQQLVKVYEKYGYHISKTSYFLCYEPPTIKSIFERLRNFDSPKEYPKFCGTFAILHVRDITTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVATLRTSGTEPKIKYYAEMCASPDQSDTALLEEELKKLIDALIENFLQPSKNGLIWRSV
What is the function of this protein?
Glucose 1,6-bisphosphate synthase using 1,3-bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1-phosphate, as acceptors.  In vitro, also exhibits very low phosphopentomutase and phosphoglucomutase activity which are most probably not physiologically relevant.
What are the official names of this protein?
Glucose 1,6-bisphosphate synthase, Phosphoglucomutase-2-like 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.