PharMolix/UniProtQA huggingface dataset:
Protein: UREG_PROMH
Sequence: MQEYNQPLRIGVGGPVGSGKTALLEVLCKAMRDSYQIAVVTNDIYTQEDAKILTRAQALDADRIIGVETGGCPHTAIREDASMNLAAVEELAMRHKNLDIVFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITHSDLLVINKIDLAPYVGASLEVMEADTAKMRPVKPYVFTNLKEKVGLETIIDFIIDKGMLRR
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_ANADF
Sequence: MPTISQLVRKGREKLLTKKKAPALKESPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGTLDAVGVQGRKQGRSKYGAKRPS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: AC4_PYMVV
Sequence: MGNLISTFLSSSKGNSTAQITDCSIWCPRPGQHISIRTFRELNRAPMSNPTSRKTGTVSNGDCSRLTEEVLEADSRHQTTQLPRH
What is the function of this protein?
Pathogenicity determinant (By similarity).  May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein AC4, Protein AL4.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AC4/C4 family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor. Note=Localizes to the cell periphery.
Protein: GIP1_PHYSO
Sequence: MKVFPALTSALVALGTAGVEAEHVQRSLVMGGGTVPVGAKTYTVGLRTTAEGDTFCGGALISPTHVLTTATCTASLGSGPAEWAAVGTHYLNGAKDGERLKVVSAQNHTLYNPNNFAYNFAVLTLEKPSKFSPVKLPAADGSDIAPSMSSKLMGWGDTSYPNGARANELQSVELRVVTSNCTYTVGPSEVCAGGEEGKDKCAGDTGGPLIKENGSGDADDILIGLASWGMPCGHKDVASVYARVSAGLEWINSVIKK
What is the function of this protein?
Secreted effector that suppresses host plant glucan elicitor-mediated defense responses (PubMed:12084830, PubMed:15545660).  Targets host endoglucanase EGaseA and inhibits the EGaseA-mediated release of elicitor-active glucan oligosaccharides from P. sojae cell walls (PubMed:12084830, PubMed:15545660).
What are the official names of this protein?
Glucanase inhibitor protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_AVALA
Sequence: MTNIRKIHPLMKIMNNSFIDLPAPSNISSWWNFGSLLGACLALQIVTGLFLAMHYTADTTTAFSSVTHICRDVNYGWVIRYLHTNGASMFFLCLFIHVGRGLYYGSFSLSETWNIGIILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPLIIAALVMVHLLFLHETGFNNPLGVSSNPDKIPFHPYYTTKDLLGVILLILPLMTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGEVLALISSILILAIIPLLQTAKQQSMMFRPLSQCLFWVLVADLYTLTWIGGQPVENPFITIGQAASILYFSLILIIMPMVSLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYFB_WOLPM
Sequence: MKFTLSWLLEYLETNASLEEITDKLTHIGLEVEDVIDNSRLTGFIVAEVLEVVPHPNADKLKLCKVDDGSKILQIVCGANNVREGMKTVLASLGSTLPESDFTIKPTKIRGVLSEGMLCSASELALVQEESEGIIELSDDYKVGDKFFNCDPVIDINVTPNRGDCLGIYGIARDLAATGIGTLKTLSIPQLTSSINSPIDVEVTDGESFISGIYIANVKNQESPKWLKDRLESIGMRSISAIVDITNYIMISFSRPMHAYDAKKIEGELTVRKANDGEKFAGLNGKEYLLNKDISVIAGDKNIHGIAGIIGGKCSECTLETTDIFLESAWFDPISITKSSRQLGISTDASYRFARSVDPEFTFDGLNLAAKMILDLCGGETSSVVSAGSLDSADTKVSFDYQDVNKFGSVSVSPDEVLDILTKLGFSIDKKTEGNWNVQVPSWRPDVTIPADLIEEVTRIYGYDKIKEEPLPNNVEEVDSTYDNLRILMTNRGFHEVLTWSFMSESTAEKFGYSNKLFIIDNPFNNSFNIMRPSIMPNLLQVTADNIAHGISDLAIFEIGPIYDGEAQSKYVLSGIRSGNNLPRNHYNTDRKVDVFDAKADCIAALEFFNVNCDNLTIEKAEKEHYHPGKSGTLSFKNKVAGYFGELHPNILDLFDIKQKVVGFEVILENIENLPVSRKKFIDYKYQSVKRDFAFIVNKDVEVGNIINVIKKSSELITEVLIFDVYHGNNIEPNKMSIALSVTFCSPIHTLTEKEIQKESSAIVNLVCENTGGTLRTYR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_CAMC5
Sequence: MRCVHFGECGSCTLALPYEDQLNFKANFIADKFREFFDGELEIFSSKPQRYRSRAEFGIWHENDEIYYTMHGSRSKFIKISECLKVDESIAALMPRLLEELGTSNELKSKIFGVEFISTSELCAVILLYHKRLEGLEAAFSELAKRLGVKIVARSRGQKISSDERELCDSFEINGLRYALNFGDSAFIQPNKCVNEKMISWAMNAVQNAEDMLEMYCGHGNFTIPLAGKFRRVLATEISKSSIANALKNCERNGIGNIKFLRMSAEELMSAFSGERGFRRLEGVNLADFTFSHVLVDPPRAGLEASVINFIKNYENIVYISCNPQTLYENLKELSLTHKATKFAMFDQFANTNHIECGVVLKKR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RL3_SYNJA
Sequence: MALGILGRKVGMTQIFSPEGLAIPVTVVQAGPCTVTQIKTQATDGYNAVQLGYWPTAEKHLTRAQRGHLSKAGVTELLRHLREFRVDQPEAYQLGQKITVEIFSPGQLLDVAGTSIGRGFAGYQKRHHFGRGPMSHGSKNHRRPGSVGAGTTPGRVFPGLRMAGRMGGCRVTIRKLQLVQVDPERNLLIIKGSVPGVEGGLLEITPAKQVGNKR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ESF2_ASHGO
Sequence: MSDNDSDVQDFSSEEEDHGLLIDRKKQQTLDFAQDGSDSEGGSDLDDDDIAEEESPIQNETKAATGEEPATADGDNIAPQSADELRPEERADQLKQERLRRLKKLKASKKSNHKTGVVYLSKIPPYMKPAKMRQILSRFGDLDRLFLKREDEHSHRQRVKGGGNKKVMFREGWAEFIRKKDAKLCAETLNGNIIGGKKGNFYHDDVMNVKYLSGFKWADLTEQIARENDVRQSKLQLEISQANKLNAEFIRNVEKSKMLNNIRAKKHKDEDSSERTESHLPVKQRKVTSNRASAPESQKQPASEKLSNVLHNLF
What is the function of this protein?
Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis.  Required for the early cleavages at sites A0, A1 and A2 (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein ESF2, 18S rRNA factor 2.
What is the protein family that this protein belongs to?
Belongs to the ESF2/ABP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YIDX_ECOLI
Sequence: MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQSDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDARFVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKNMDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
What are the official names of this protein?
Uncharacterized protein YidX.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LEP4_BACSU
Sequence: MLSILFIFGLILGSFYYTAGCRIPLHLSIIAPRSSCPFCRRTLTPAELIPILSFLFQKGKCKSCGHRISFMYPAAELVTACLFAAAGIRFGISLELFPAVVFISLLIIVAVTDIHFMLIPNRILIFFLPFLAAARLISPLDSWYAGLLGAAAGFLFLAVIAAITHGGVGGGDIKLFAVIGFVLGVKMLAAAFFFSVLIGALYGAAAVLTGRLAKRQPLPFAPAIAAGSILAYLYGDSIISFYIKMALG
What is the function of this protein?
Plays a role in type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.  Substrates include proteins required for biogenesis of the type II general secretory apparatus.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase, Late competence protein ComC.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSXA_ECO45
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTMAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECB1_FRAT1
Sequence: MQNNEIQPSFLIQKVYTKDVSFETINSPACFKEQWNPSSDFNIDINTTKINDENFELDLTITVTTKNNETNAYIAEVTQSGIFTITSMSEEQIDSVLNTYCANTLFPYAKRIIDSSIIKGGFLPLNLAPINFDAIYLQKKSSPKREH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 1.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SALSV
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FPG_GEODF
Sequence: MPELPEVETIRRAVGPQVRGKRIIHTNVRATKLRHPLPPELDRLLVGQLIVAMDRRGKYLLLRCKGGTIIFHLGMTGMLYLVKASSPHGKHDHLDLVLDGSYILRFTDPRRFGTIIWTDNDPLQHPLLVAHGPEPLEAEFSASYLYLKRHRRKIPIKQLIMDSRVVAGIGNIYANESLFRAGIAPQTSASDLSPDKDLLLVDAIKGVLTDAVEAGTSNIESALTGERPQGYFPYEFSIYGKKGRPCPKCGSAIRMMRLGGRSTFFCPLCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RR4_EUCGG
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPQARQLVNHRHILVNGCIVDIPSYRCKPRDIITARDDQKSRAMIQNYFDSSPHEEVPKHLTLHPFQYKGLVNQIIDSKWIGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNAJ_METMA
Sequence: MATKRDYYEILGLSKDSSVEDIKKTYRKLALQYHPDRNKEPGAEEKFKEISEAYAVLSDAEKRAQYDRFGHAGIDNQYSAEDIFRGADFGGFGDIFEMFFGGGRRGGPMGPRRGSDLQYDLYVTFEEAAFGVRKDIDIPRTERCSTCSGTGAKPGTSPKRCPNCGGTGQVRTTRSTLGMQFVSTTTCSACHGRGQVVESPCPTCSGAGRVRSRRKMSVNVPAGADSGMTLRLSGEGDAGEPGAPSGDLYIIVHVMEHKYFKRVDYDVISELPISFTQAALGADIMVDTLYGKVKMNIPSGTQTHSVFRLKDKGIQRLQGHGKGDQLVRVIIRTPTKLTQEQKDLLHQFEYLSNGKKPEAEERSRSDKQKSEKPRKSKGLFEKVKDAFES
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_VIBVY
Sequence: MKLPIYLDYSATCPVDPRVAEKMVQYMTMDGTFGNPASRSHRYGWQAEEAVDTAREQIAELLNADPREIVFTSGATESDNLAIKGAAHFYSKQGKHVITSKTEHKAVLDTCRQLEREGFEVTYLEPESNGLISLSKLEAAMRDDTVLVSIMHVNNEIGVIQDIEAIGELCRSRKIIFHVDAAQSAGKVAIDVQKLKVDLISLSAHKIYGPKGIGALYVRRKPRIRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAFRIAKLDMEKDYQHALALRNRLLDGVKDMEAVTINGDLDQRVPHNLNISFAFVEGESLLMSLKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSFGRFTTEEEIDYAIEQIRVAVAKLRDMSPLWDMYKEGIDLNTVEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_PECAS
Sequence: MKAIVFAYHDIGCVGLEALALAGYEIQAVFTHSDAPGENHFYASVAKTAAGMDVPVFAPEDINHPLWVNRIRELAPDVIFSFYYRTILSDDILQLPSFGAFNLHGSLLPRYRGRAPVNWVLVNGETQTGVTLHKMVSRADAGDIVAQSVVAIDDEDTALTLHGKCRTAAATLLAQQLPLIRSREIALTPQDDSQASYFGRRTAADGLIDWQKSAHEINNLIRAVTEPYPGAFTFLGERKVIIWRARVVKNNRVNVNHPHGGDAGSIISTSPLVVSCGEDALEIVSGQSEAGLYMSGSRLAAEMGMVPQARLGNLASRVQRRRTRVLILGVNGFIGNHLTERLLRDDRYEIYGLDISSDAIARFLGDPRFHFVEGDISIHNEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVRYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAKNGLRFTLFRPFNWMGPRLDTLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRVIENRNGQCDGQIINIGNPHNEASIRELGEMLLTSFNAHPLRDRFPPFAGFIDVESSSYYGKGYQDVAHRTPSIRNAKRLLEWEPTVKMEQTVAETLDYFLRTVDVPHTADATDTQG
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: CON10_NEUCR
Sequence: MAGTGNDNPGNFANRPKEEVQAIASKGGQASHSGGFASMDPEKQREIASKGGKASSGSFEPGSEKAREAGRKGGKASGGTGADDDE
What are the official names of this protein?
Conidiation-specific protein 10.
What is the protein family that this protein belongs to?
Belongs to the con-10 family.
Protein: DSZB_RHOSG
Sequence: MTSRVDPANPGSELDSAIRDTLTYSNCPVPNALLTASESGFLDAAGIELDVLSGQQGTVHFTYDQPAYTRFGGEIPPLLSEGLRAPGRTRLLGITPLLGRQGFFVRDDSPITAAADLAGRRIGVSASAIRILRGQLGDYLELDPWRQTLVALGSWEARALLHTLEHGELGVDDVELVPISSPGVDVPAEQLEESATVKGADLFPDVARGQAAVLASGDVDALYSWLPWAGELQATGARPVVDLGLDERNAYASVWTVSSGLVRQRPGLVQRLVDAAVDAGLWARDHSDAVTSLHAANLGVSTGAVGQGFGADFQQRLVPRLDHDALALLERTQQFLLTNNLLQEPVALDQWAAPEFLNNSLNRHR
What is the function of this protein?
Catalyzes the third and final step of the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds.  Oxidizes 2-(2'-hydroxyphenyl)benzene sulphinate (HBPS) to 2-hydroxybiphenyl (HBP) plus sulfite (PubMed:7961424, PubMed:7574582, PubMed:9634856, PubMed:9308179, PubMed:31545606).  The rate-limiting step of the '4S' desulfurization pathway (PubMed:9308179, PubMed:31545606).  The pathway substrate specificity has been augmented using mutagenesis, however no mutations allowed use of alkylated thiophenes (PubMed:11823208).
What are the official names of this protein?
2'-hydroxybiphenyl-2-sulfinate desulfinase, 2-(2-hydroxyphenyl)benzenesulfinate desulfinase, HPBS desulfinase, Dibenzothiophene desulfurization enzyme B.
What is the protein family that this protein belongs to?
Belongs to the DszB desulfinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_STRA3
Sequence: MAIILPDLPYAYDALEPHIDAETMTLHHDKHHATYVANANAALEKHPEIGEDLEALLADVSQIPEDIRQAVINNGGGHLNHALFWELMSPEETQISQELSEDINATFGSFEDFKAAFTAAATGRFGSGWAWLVVNAEGKLEVLSTANQDTPIMEGKKPILGLDVWEHAYYLNYRNVRPNYIKAFFEIINWNKVNELYQAAKA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: CDPKT_ARATH
Sequence: MGFCFSKFGKSQTHEIPISSSSDSSPPHHYQPLPKPTVSQGQTSNPTSNPQPKPKPAPPPPPSTSSGSQIGPILNRPMIDLSALYDLHKELGRGQFGITYKCTDKSNGREYACKSISKRKLIRRKDIEDVRREVMILQHLTGQPNIVEFRGAYEDKDNLHLVMELCSGGELFDRIIKKGSYSEKEAANIFRQIVNVVHVCHFMGVVHRDLKPENFLLVSNEEDSPIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLHRNYGKEIDVWSAGVMLYILLSGVPPFWGETEKTIFEAILEGKLDLETSPWPTISESAKDLIRKMLIRDPKKRITAAEALEHPWMTDTKISDKPINSAVLVRMKQFRAMNKLKKLALKVIAENLSEEEIKGLKQTFKNMDTDESGTITFDELRNGLHRLGSKLTESEIKQLMEAADVDKSGTIDYIEFVTATMHRHRLEKEENLIEAFKYFDKDRSGFITRDELKHSMTEYGMGDDATIDEVINDVDTDNDGRINYEEFVAMMRKGTTDSDPKLIR
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 29.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: GLO2_LEGPC
Sequence: MTILPISAFSDNYIWAFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHIGGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYYEPQKGWLFCGDTLFSAGCGRVFDGTIEELHESLLLFKKLPRNTKVFCAHEYTLQNLKFAHTVEPCNSSVINYMQQILKQPSPCTLPSNIDLELSINPFLRTDKEQVKQYALSHGANSSDSLDVFKVLRNQKNSFK
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CLCB_ECOSM
Sequence: MFRRLLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLFAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YP174_YEAST
Sequence: MGIQEKTLGIRKERKLVVVPRERNHVRHASQRTRSKNYKNISKKRAQQHAFGFNIAKTLAKIQAFVWGSPADEEEESVVPLSKNSQDCVPLQWQAKFAQLRQQLHSTQKELQFVKEKCHLLQSVLDDANIDQRYLESRRDMKNIERDNLKPTENLPPSPVRAVNPLVTSSPIHMSPLQSRQRPVSSLQPPKGPNFYAKYPKLPQTNILRESPTEDSVPHAE
What is the function of this protein?
Specialized component of the nuclear membrane that may be involved in the connection of the spindle pole body (SPB) to the nuclear envelope.
What are the official names of this protein?
Nuclear envelope protein YPR174C.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: QGDA_PSEPU
Sequence: MRQTGLASLPLKSLAVAVLLSLAGTPALAADIPANVDGARIIAADKEPGNWMSTGRTYDEQRYSPLKQISDQNVGQLGLAWSYKLDLDRGVEATPIVVDGAMYTTGPFSVVYALDARDGRLIWKYDPQSDRHRAGEACCDAVNRGVAVWKGKVYVGVLDGRLEAIDAKTGQRAWSVDTRADHKRSYTITGAPRVVNGKVVIGNGGAEFGVRGYVTAYDAETGKEAWRFYTVPGDPKLPPEGKGMEIAAKTWFGDAYVEQGGGGTAWDSFAYDPELNLLYIGVGNGSLWDPKWRSQAKGDNLFLSSIVAVNADTGEYVWHYQTTPGDAWDYTATQHMILAELPIDGKPRKVLMQAPKNGFFYVIDRATGELLSAKGIVPQSWTKGMDMKTGRPILDEENAAYWKNGKRNLVTPAFWGAHDWQPMSYNPDTGLVYIPAHIMSAYYEHIPEAPKRNPFKSMYQLGLRTGMMPEGAEGLLEMAKSWSGKLIAWDPVKQQAAWEVPYVTIFNGGTLSTAGNLVFEGSADGRVIAYAADTGEKLWEQPAASGVMAAPVTYSVDGEQYVTFMAGWGGAFSTFAGALSLRAGVQPYAQVLTYKLGGTAKLQEPAPRPDTPKPPALSNDTASIEAGAKLYDGYCSQCHGIHAVSGGVLPDLRKLTPEKHQMFLGILFGGRVPDGMPSFADAFTPEQVDQIHQYLIKRAHDLHQEGDTWKQFSAKSSH
What is the function of this protein?
Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids.  Active with primary alcohols, glycerol, 1,2-propanediol, 1,3-propanediol but not with methanol or sugar alcohols such as D-sorbitol.
What are the official names of this protein?
Quinohemoprotein alcohol dehydrogenase ADH-IIG, ADH IIG, Alcohol dehydrogenase (azurin).
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Periplasm.