PharMolix/UniProtQA huggingface dataset:
Protein: NU4M_TETNG
Sequence: MLKILIPTVMLIPTAWLAPTKWLWPTTLLHSLLIALASLSWLKNASETGWSSLNPYMATDPLSTPLLILSCWLLPLMILASQPNHTAHEPINRQRMYISLLTSLQFFLILAFSATEMIMFYVMFEVTLIPTLILITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLLQNSNGSLSLLTLLHSTPPQLSTYAAKIWWTGCILAFLVKMPLYGVHLWLPKAHVEAPIAGSMILAAVLLKLGGYGMMRILMTLEPLTKELSYPFIILALWGVIMTGSICMRQTDLKSLIAYSSVSHMGLVVGGILIQTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMALPLMTAWWFIASLANLALPPLPNLMGELMIVTSLFNWSWWTIALTGLGMLITAGYSLYMFLMTQRGPLPSHIMALEPSHTREHLLIALHLLPLLLLILKPELIWGWS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DYI3_CHLRE
Sequence: MEIYHQYIKLRKQFGRFPKFGDEGSEMLADIRPNEDHGKEYIPRNPVTTVTQCVPEMSEHEANTNAVILVNKAMSHVEGGWPKDVDYTEAEHTIRYRKKVEKDEDYIRTVVQLGSSVEDLIKQNNAVDIYQEYFTNVTMDHTSEAPHVKTVTVFKDPNNIKRSASYVNWHPDGSVPKVVVAYSILQFQQQPAGMPLSSYIWDVNNPNTPEYEMVPTSQICCAKFNLKDNNLVGAGQYNGQLAYFDVRKGNGPVEATPIDISHRDPIYDFAWLQSKTGTECMTVSTDGNVLWWDLRKMNECVENMPLKEKNSETTVGGVCLEYDTNAGPTNFMVGTEQGQIFSCNRKAKNPVDRVKYVLSGHHGPIYGLRRNPFNSKYFLSIGDWTARVWVEDTAVKTPILTTKYHPTYLTGGTWSPSRPGVFFTIKMDGAMDVWDLYYKHNEPTLTVQVSDLALTAFAVQESGGTVAVGTSDGCTSVLQLSTGLSEASPAEKANINAMFERETTREKNLEKAIKEAKVKARKEQGRRDEVKDNVTEEQLKALEDEFFKTTDPAVGGGYGAGEGAAAE
What is the function of this protein?
May play a role in regulating dynein heavy chain (DHC) activity.  May function in holding IC78 to the DHC, or in stabilizing the entire dynein complex.
What are the official names of this protein?
Dynein, 70 kDa intermediate chain, flagellar outer arm, IC69, IC70.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: RBFA_MYCSJ
Sequence: MADPARAKRLAKRISTIVASAIEYEIKDPRLAGVTITDSKVTNDLHDATLYYTVLGRSLDEEPDYAGAAAALEKAKGVLRTKVGAGTGVRFTPTLAFVRDTVPDTAHRMEELLARARAADEDLARVREGAKHAGDADPYRVSGVEEEAGGSGEVQAEFDAEDTGDRNRQDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_PYRTR
Sequence: MAPRCLLIGTPSIAAHPERLDQVYEIHHRSSTDLQMLDRIAAGLVNLPAATYDVVLLLADADGTTRESHKLFSRDVMNKVASALKIGGVLKSQAGPFQGAEKTEAILAGLTETEDGMAKPEQEEPVSIPLKFGKNKANGVSATNGTNGAVNPDGSVPLNLNRKRDQPEPVKPAGVGFVDFSDDLDDPIITGEDDDLIDEDDLITEADMARPVVQPLECQPKPGKRRRACKDCTCGMKEKLEAEDAAKRSSADKALNSLKLDADDLAEVDFTVQGKVGSCGNCALGDAFRCDGCPYIGLPAFKPGEEVRLLNNDIQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein dre2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: VTIN_ALOVR
Sequence: DEDNVLLT
What is the function of this protein?
Has antioxidant activity.  Inhibits cyclooxygenase-2 and thromboxane A2 synthase.
What are the official names of this protein?
Verectin.
Protein: HRCA_STRP8
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ARGC_LIMF3
Sequence: MKVALIGITGYGGMVLYQMLKTHPGIDQVDLYARHLAGPTPLNQLVPNLFDDQPVYPYDSQKILANDGAVFFATPAGVTKTAARPYLTAHFPVIDLSGDYRLKNGATYEKWYHQSPAATADLKVAHYGLTDFCDATDENLIANPGCYATATLLGLAPLIIDQLIDLDTIVVDAKSGTSGAGKKPTSSTHFTQVNENAQLYNVNHHKHIPEIVQQLQAWDPAVDAIQFSTTLLPITRGILATIYAKPKPGVNKDQVVAAFKQTYATDPFVRYTGENLPTIKQVVGTNYCDLGVLFNERANTIMVASVIDNLIKGAGGQAIQNFNQRFNFAPTAGLPTAPLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZUPT_NEIMA
Sequence: MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFGLAFAGGAMVYVSLTEIFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVPNPHETLDAQDPSFQESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMPLALAIAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAVFGSVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTMGMAVIAVSLVLFHF
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCEM_ECOLI
Sequence: MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALPICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRDAERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFTLLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAGSQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIECVQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE
What are the official names of this protein?
Putative oxidoreductase YceM.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: AROC_BURL3
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMGLTEADIQIELDRRKPGTSRHVTQRQEADEVEILSGVFEGVTTGTPIALLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPIVGAGAVAKKWLRERFGVEVRGYMSGLGEIDVPFVDWSHVHENPFFSPNAAVVPELEAYMDALRKDGDSIGARIDVVASGVPVGWGEPVFDRLDADIAKAMMSINAVKGVEIGAGFESVAQRGSVHGDELTPGGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITKAGDEATVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVETPTPKIAGSAT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: COABC_BORBU
Sequence: MDKNKHILIGICGGIASYKSVYIVSSLVKLGYKVKVIMTQNATKFITPLTLETISKNKIITNLWDLDHNEVEHIKIAKWAHLILVIPATYNTISKIASGIADDALTTIISASTAPTYFAIAMNNIMYSNPILKENIKKLKTYNYKFIEPDKGFLACSSNALGRLKNEDKIIKIILNEFNQKDYLKNKKILITASRTEELIDPIRYFSNTSTGKMGFCLAQEAVKLGAQVTIITGPTNENDPEGVNIIKIKTAMEMYKEALKIYNKFEIIIGAAAVADFKPKHIFNSKIKKNKINRLYIKLVKNPDIIQHIGHNKLKNQIVIGFCAENSKNLIQKAKEKLKKKNLDFIIANELKYFGSKLNKVYIINKQSIKELPEMEKSEVAKEILKILY
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: NUD17_DANRE
Sequence: MEKVRRILVHLSKENAAPQCARFLQSITGHFVGSAEDQATVSCSLENNRFILGDRLCDGGVPLKRASFCPIKYLSDSEAVSLPSETLSRGVDVGVAVLLQSANQKLLLTRRASSLRSFPNVWVPPGGHVELDEKLLDAGLRELLEETGLNLSPDEICSRLLGLWESVYPPMLTIGLPKRHHIVTYILLKSSQTHLQIQASLRPDPAEVSACVWVDADLVKAVVSAVDGEKECVQIPADLPESIGVTKVSPDGEMSESSLPVSVLCNRAPDYGEDIERVSTGTKFALELWLKTLEHHADMG
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nucleoside diphosphate-linked moiety X motif 17, Nudix motif 17.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: Y6650_DICDI
Sequence: MSNNESYEILKFGLEHFDKEGKNNNHNNNNNNNNNNNTFNIFETHIESLRNESKMLSELLKKNLQSELLNLPNSIRKMSMEEFLQHCLDIDAINVTSVPTLINNKDNNSETEQQQQQQQNGNNGLSLTELLFSPEKSVNEIDNSNSNTSIDSESMNNIKQKVIDILNSPQLILKKKGFNSNNNL
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285671.
Protein: RUVB_PROM1
Sequence: MAIVSSITNHSSLPNDKGEERLVGPSLLREELKLSQQDSLRPKSFDDFVGQSELKKVLEISVKASLKRGEALDHLMLYGPPGLGKTTMALVIAEELGVKARVTSAPALERPRDIVGLLINMQPRELIFVDEIHRLNRISQELLYPAMEDRRLDLTVGKGTSSRMRSIEIPPFTLVGATTKPAALSSPMRDRFGITQRLDFYNYLDLENIIKRSAKLINLVISEEASQQLAKRCRGTPRIANRLIRRVRDYAEVYSHSKKIDVEVVNDALDLHRVDQRGLDATDRSYIGLLVNQYQGGPVGLETLAAGLGEDSTTLETVVEPYLMQIGFLQRTSRGRVVTPAAKKHYLLTSPNNIDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y6316_BRASO
Sequence: MLICVPGILSKDDVAEFRHIMAESDWEDGRSTAGAQSAMVKRNEQLPPDSEVARRLGHRIISAMTANPRFLAAAIPQQIFPPLFNRYAADAGHQFGIHVDNAVRGDKLTGLRIRTDLSVTLFLSEPDEYDGGELVIEDLYGSHEVKLPAGDLVLYPASSLHMVTPVTRGVRVASFFWLQSMIRDPLARSMIFDLDTTIQGLSQRMGRDDPEMVRLTGLYHNLIRYWAET
What are the official names of this protein?
PKHD-type hydroxylase BRADO6316.
Protein: MOAC_SHESM
Sequence: MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKAE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: NUOH_AROAE
Sequence: MEALLEPVVQLFGPAWPAVWTLTKIVAIIAPLMLCVAYLTLAERKVIGYMQVRIGPNRVGPKGLLQPIADGMKLLFKEIIVPTGASKGLFILGPILAIAPSLAAWAVVPFGEGMVLADVNAGLLFLLAITSVEVYGVIIAGWASNSKYPFLGSMRAAAQMVSYEVAMGFALICVLLISASLNLTDIVRSQGQGQFHEMGLSFLSWNWIPLFPMFIVFLISGIAETNRAPFDVVEGESEVVAGHMVEYSGMAFALFFLAEYANMILVSILTSVLFVGGWLSPVSFLPDGFFWLALKTAFFLFVFLWARATFPRFRYDHIMRLGWKVFIPITLVWVIVVAVWMMSPLSIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FIS1_NEUCR
Sequence: MTQLPYAVDAETPLNPAELNVLRAQYEKEGEMVGVQTKFNYAWGLVKSNVRADQHLGVMLLSEIFRTSPERRRECLYYLALGNYKLGNYAQARKYNDALLENEPANLQAANLRALIDDKVTKEGLMGVAIISGVAVAAGVIGGVLLRNLGRKR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein, Mitochondrial transmission protein 2.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: GCSH_TREDE
Sequence: MEIKEDVKYLESHEWFKKEGNIGIIGISDYAQSEMGDVVFIELPEVGDEVTADKACATVESVKAVFEIISPMTGKVVEINEELLDAPEKINEDAFGSWFFKVELKGESSKLMDAGKYKGLCK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HMUV_PHOLL
Sequence: MNAIKNNISLQAQNLSYSIGNQKIIDNVSLSVNKGEIVAIIGPNGAGKSTLLRLLTGYIKPEHGQCDLHGTPIEQWPAEQLARTRAVMRQHSSLSFPFSVEEVVAMGRSPHGIHHKQTAIDTVIEQTDCQALRHRDYRQLSGGEQQRVQLARVLAQLWHPTPIECCLFLDEPTSALDLYHQQHTLRLLYRLTREQPMAMCCVLHDLNLAALYADKIFLLHKGKLVAAGTPEEVLNDHTLRKWYQADLGITRHPETQQPQIYLRQ
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLMU_SHEB9
Sequence: MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLKASLGEQQLNWVLQAEQLGTGHAVAQASPHIADNDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLANPMGYGRIVRTPCEGQEQGKVIGIIEQKDATAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHADGVAIDTAQPQSAIEVEGANNRVQLAQLERAYQAREAEKLMLAGANLRDPSRIDIRGDVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEGAKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAIIGDGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYT7_ARATH
Sequence: MDMRRASMCMMLICVSLVLLSGFGQFVICSEEKGTYNDNVVKMKLGGFSDSKNDWNGGKEIDDIALFAVQEHNRRENAVLELARVLKATEQVVAGKLYRLTLEVIEAGEKKIYEAKVWVKPWMNFKQLQEFKNIIPSFTISDLGFKPDGNGFDWRSVSTNNPEVQEAAKHAMKSLQQKSNSLFPYKLIDIILARAKVVEERVKFELLLKLERGNKLEKFMVEVMKDQTGKYE
What is the function of this protein?
Specific inhibitor of cysteine proteinases.  Probably involved in the regulation of endogenous processes and in defense against pests and pathogens (By similarity).
What are the official names of this protein?
Cysteine proteinase inhibitor 7, AtCYS-7.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_BRUA1
Sequence: MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYRVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFAAMIEKAGFERVSYRNFTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: CDPKV_ARATH
Sequence: MGCYSSKNLKQSKRTILEKPFVDIGKVYILGDELGQGQFGITRKCVEKTSGKTYACKTILKTNLKSREDEEAVKREIRIMKHLSGEPNIVEFKKAYEDRDSVHIVMEYCGGGELFKKIEALSKDGKSYSEKEAVEIIRPIVNVVKNCHYMGVMLRDLKPENFLLSSTDKNATVKAIDFGCSVFIEEGEVHRKFAGSAYYIAPEVLQGKYGKEADIWSAGIILYILLCGKPPFVTEPEAQMFSEIKSAKIDVDSESWKFIDVKAKHLVNRMLNRNPKERISAAEVLGHPWMKDGEASDKPIDGVVLSRLKQFRDMNKLKKVALKVIAANLSEEEIKGLKTLFTNIDTDKSGTITLEELKTGLTRLGSNLSKTEVEQLMEAADVDGNGTIDIDEFISATMHRYRLDRDDHVYQAFQHFDKDNDGHITKEELEMAMKEHGVGDEVSIKQIITEVDTDNDGKINFEEFRTMMRSGSSLQPQRELLPIK
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 31.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: MUTL_BUCBP
Sequence: MFIKILPLSTSSYISAGEVICNPASVVKELMENSIDSSATCIHIEIKKGGLQSIVVKDNGCGIDKSDLKASLLHHATSKIYSVCDLNNITTLGFRGEALASISAVSRIILSSCNISSKKVGWSIYSDGFGVISVPKLVVHNKGTICTVLDLFFNRPVRQKTIKSEYSEFLRIDEIVRSLSLSNNKLSVSLRHNDKLIRYYDNCNIDFCNINMLNAIYGLSSVIKVVPVDYFLNTMKITGWLYLLGSYHTSKKKFQYFYINGRIILNRSVHHAVYQAVSEINHYQYSVSYILYLKLNCNELDVNIHPAKKIIKIINIRLIHVFICQAILYSLKKECILKKDCTKIIKNISNNKKKNNLNYNFQSNLDITSCIVQENSYSIPQKLFNLDNVSIIETELKFKRFKCKDYLNTIFGNVLMVIKNFYLLIEKNDELFLFFLPRAKSLICELKLKFGVKNGLLIKKLRKKYFYFFKNNTEYHFFLRFYEILSHVGLNFNITLKYAELNSIPFMIDDTNLGIIISEILYFFKIKREMSLSRLVTTIMNHSKILVKYWDHLQVLSVISECEKYYKSILELNVISYILQPINFDSTVNFFKNDSKV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DHB7_MOUSE
Sequence: MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIVQMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIWTLLLPIMWLLRFFVNALTVTPYNGAEALVWLFHQKPESLNPLTKYASATSGFGTNYVTGQKMDIDEDTAEKFYEVLLELEKRVRTTVQKSDHPS
What is the function of this protein?
Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis (PubMed:9658408, PubMed:12732193, PubMed:12829805, PubMed:20659585).  Catalyzes the NADP(H)-dependent reduction of estrogens and androgens and regulates the biological potency of these steroids.  Converts estrone (E1)to a more potent estrogen, 17beta-estradiol (E2) (PubMed:9658408, PubMed:12732193).  Converts moderately dihydrotestosterone (DHT) to their inactive forms 5a-androstane-3beta,17b-diol and 5alpha-androstane-3alpha,17beta-diol (PubMed:12732193).  Does not metabolize progesterone (PubMed:12732193).  Additionally, participates in the post-squalene cholesterol biosynthesis, as a 3-ketosteroid reductase (PubMed:12829805, PubMed:20659585).
What are the official names of this protein?
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7, 17-beta-hydroxysteroid dehydrogenase 7, 17-beta-HSD 7, 3-keto-steroid reductase, Dihydrotestosterone oxidoreductase, Estradiol 17-beta-dehydrogenase 7.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Colocalizes with HMGCR in a wide range of tissues during embryonic development.
Protein: IHFA_YERPA
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.