PharMolix/UniProtQA huggingface dataset:
Protein: RECA_FRAP2
Sequence: MSKEKALESALSQIEKQFGKGSIMRLGDQETAHDIDVIPSGIIALDVALGIGGYPKGRIIEIYGHESSGKTTLTLLAIAQCQKQGGVAAFIDAEHALDPKYAKLLGVDVDNLIVSQPDTGEQALEIADMLVRSGGIDIVVIDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTANIKRSNTLVMFINQIRMKIGVMFGNPETTTGGNALKFYASVRLEVRKGGSIKDGVDVSGNEIKVKIVKNKVAPPFKQAEFELIYGEGISLEAELIDLGAKYEIIEKSGAWYSYKGKKIGQGKEKSKEYLKENTLERDEIEKALLQLLLPQKYAVQEQVQPEPKSKQSKSKQASEQATQDELI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_KLEP3
Sequence: MHNQAPIQRRKSKRIYVGNVPIGDGAPIAVQSMTNTRTTDVAATVSQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRTVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIDQLEARIRAKASMLDEARRIDVQQLEAK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CYSJ_SHIDS
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENIAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQTAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSDLRYQPGDALGVWYQNDPALVTELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGEKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRTRAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: ECCC5_MYCMM
Sequence: MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLIVVGVVVVGLLGGMVAMVFASGSHVFGGVGSIFPIFMMVGIMMMMFRSVGAGGQQQMSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPAPSTLAAAVGSPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGKALQEFGRYQSVVYNLPKMISLLVEPWYALVGEREQALGLMRAIICQLTFSHGPDHVQFIVVSSDLAEWEWVKWLPHFGDSRRYDAAGNARMVYSSVREFAAEQGELFAGRGSFTPRHASSSAQTPTPHTVIICDVDDPQWEYVISAEGVDGVTFFDLTGSPMWTNVPERKLEFDKTGVIEALPRDRDTWMVIDDNAWFFALTDHVSIAEAEEFGQKLAQWRLAEAYEEIGQRVAHIGARDILAYYGIDDPGNIDFDYLWGSRTDSMGRSRLRAPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLGHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAGVDDAKEYNSVRGRMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGRAYWIHLMMASQTIESRAEKLMENMGYRLVLKARTAGAAQAAGVPNAVNLPAQAGLGYFRKSLEDIIRFQAEFLWRDYFQPGITVDGEEAPVLVHSIDYIRPQLFTNSFTPLEVTVGGPEIDKVVAHANGEVVEEVEAEAEEEGIRVPKVGTVIIDQLRRINFEPYRLWQPPLTQPVAIDDLVNRFLGHPWQKEYGSARNLVFPIGVIDRPFKHDQPPWTVDTSGPGSNVLILGAGGSGKTTALQTLISSAALTHTPDQVQFYCLAYSSTALTTVSKLPHVGEVAGPTDPYGVRRTVAELLALVRERKRSFLEYGIASMEMFRRRKFGGEAGPVPNDGFGDVYLVIDNYRALAEENEVLIEQVNLIINQGPSFGVHVVVTADRESELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYVRLDSDPQAGLHTLVARPAMGSTPTNVFECDSVVAAVSRLTTSQAPPVRRLPASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVYLNFAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPSAQVWLIDPRRQLLTALGSNYVERFAYNLDGVQAMMGELAAVLAGREPPPGLSAEELLSRSWWSGPEIFLIVDDIQQLPPGFDSPLHKAAPWVNRAADVGLHVIVTRSFGGWSSAGSDPMLRALHQANAPLLVMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVALTEVRK
What is the function of this protein?
Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins (PubMed:19602152, PubMed:22925462).  This component is essential for ESX-5 complex stability and secretion (PubMed:22925462).
What are the official names of this protein?
ESX-5 secretion system protein EccC5, ESX conserved component C5, Type VII secretion system protein EccC5, T7SS protein EccC5.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YR901_MIMIV
Sequence: MYDVLPPELWVKIVDYSGEISLLLTNTSFFELFNLVNLKISVIKYVVENNLICVLKYLVLLKEIKHPIMDKTIMTTKSLNKFLIKSSKKGQLKIVECLVSLGADIKSLNNCALGLASENGHLEVVEYLVGQGANVRSNKNYAIIWASRNGHIEVVEYLVSQGANISAEDNLAIRWASQNGHLEVVKYLVSLNANIRADNDYAVRWASQNGHLEIVKYLVGQGANIRANDDYAVRWASINGHLEVVKYLVSQDADIRALDNSAVKCASRNGHLKVVEYLVSSGADITVENNCAIGLASRNGHLEVVKYLVAQGTDIRAENNYAIKLASLNGHLEVVKYLVSVGADIKADNNFSVSQGAILVN
What are the official names of this protein?
Putative ankyrin repeat protein R901.
Protein: CSRN1_MOUSE
Sequence: MTGLLKRKFDQLEEDDSSSSSSSSFSSRLSLSSFPASSASPAWNSDEEGPGGQAPQSDQDSCGLQSFTPPSILKRAPRERPGHVAFNGITVYYFPRCQGFTSVPSRGGCTLGMASRHSTCRLFSLAEFTQEQVRARREKLRRRLKEEKLEMLRWKFSVAGVPESGAGVPLTADAIDDASVEEDLAVAVANGRLEEANFLQPHPPRQRRALLRASGVRRIDREEKRELQVLRQSREDCGCHCDGVCDPETCSCSLAGIKCQMDHTSFPCGCCREGCENPNGRVEFNQTRVQTHFIHTLTRLQMEQGAESLGDLESPVEDTPVEQAALSPFPPSKPPVSSELGDSSCSSDMTDSSTTLSSGSSEPPNHPAHPSLPGPSFRSGVDEDSLEQILNFSDSDLGIEEEEEEGGGVGNLDNLSCFHLADIFGTGDPGSLASWTHSQSGSSLASGILDENANLDASCFLNSGLGGLREGSLPGSSGSPEGDAVQSSSWDLSLSSCDSFELLQALPDYSLGPHYTSRRVSGSPDSLETFHPLPSFSPPRDASTCFLESLVGLSEPVTEVLAPLLESQFEDAALAPLLEPVPV
What is the function of this protein?
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity.  May have a tumor-suppressor function.  May play a role in apoptosis.
What are the official names of this protein?
Cysteine/serine-rich nuclear protein 1, CSRNP-1, Axin-1 up-regulated gene 1 protein, TGF-beta-induced apoptosis protein 3, TAIP-3.
What is the protein family that this protein belongs to?
Belongs to the AXUD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRR_MYCTA
Sequence: MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRVVLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPLASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RL35_LISMO
Sequence: MPKMKTHRGSAKRFKRTGSGKLKRRHGFTSHMFANKSQKQKRKLRKSAMVSAGDFKRIRQMVAKMK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GATA_CHLPB
Sequence: MYFSSYQNLRKRLLSREISCETVVLDYLERIRKNHERNVYITVFNDQALQRAKELDRKLEAGEQPGRLFGLPMAVKDNLSVKDASLTCASKILEGYTAVYNATAVERLLKEDAVFLGKVNMDEFAMGSSNENSAFGPVPNPYDDSRVPGGSSGGSAAAVAGDLAMVALGSDTGGSVRQPAGFCNVVGLKPTYGRISRYGLVAFGSSFDQIGILSRNCDDAALVLGVIAGKDAADTTSSQHVVPDYLSEMGSVSLKGMKIGVPEEYFPETLDPGVALAVRNRLEELRDAGAELVDIALPESDHAIAAYYILTTAEASSNLARFDGARYGYRSGDASDLSGMYVNSRSEGFGGEVKRRIMLGTYVLSAGYYDTYYKKAQQVRRVFLDRYKEALAKVDVIAGPTSPFPPFGIGDKMDEPLEMYLADVFTVPASIAGLPALSVPAGFDRSGLPVGLQLIGDFFDEGKLLGIAREIQRSQEE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS15_FRATM
Sequence: MLTAQDKQKIIKENQLAESDTGSPEVQVALLTARINDLQGHFEAHKKDNHSRRGLLRLVSQRRKLLDYLHDKDVERYRSLIKKLNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MED19_SCHPO
Sequence: MAQAPEYHYVGSVDYQPTRPSAHQNLIELYGLTELAKKVGRVDEFGNKRKMRRSYKAYIQDLPGYNEILRDNTIKQWLTNPIREEVPIDIEFLHHVFSVEPGIIPGFNPKVFGLEDDVVMGNVSRDSSQPRSPSRRKK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19, RNA polymerase II mediator complex protein rox3.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_THEPX
Sequence: MRLKPLGDRVVVKVIQAEEVTKGGVILPGTAKEKPQQGEVVAVGTGQYIDGKKVELEVKVGDRVIFSKYAGTEVKLDGEEYLLLRESDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML7_ARATH
Sequence: MDPTELKRVFQMFDKNGDGTITGKELSETLRSLGIYIPDKELTQMIEKIDVNGDGCVDIDEFGELYKTIMDEEDEEEEDMKEAFNVFDQNGDGFITVDELKAVLSSLGLKQGKTLDDCKKMIKKVDVDGDGRVNYKEFRQMMKGGGFNSL
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Calmodulin-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: WZYE_ECOL6
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADAPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_XANC5
Sequence: MRHQKSGRKFNRTSAHREAMFRNMAASLFKHELIKTTLPKAKELRRVAEPLITIGKVDGVANRRLAFARLRDKEAVGKLFVELGPRYATRPGGYLRILKAGFRAGDNAPMAYVELVGRPVVAEEVAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RIMO_JANSC
Sequence: MSQNPPLLRPDLARARVPDDARPGQPRIGMVSLGCPKALVDSERILTRLRAEGYAISPDYTGAEAVIVNTCGFLDSAKLESLEAIGEALEANGKVIVTGCLGAEPEYITGAHPTVLAVTGPQQYEQVLDAVHGAVPPAPDPFIDLLPPAGVKLTPRHYAYLKIAEGCDHKCKFCIIPDMRGKLVSRPQTAVMREAEKLVDSGVKELLIISQDTSAYGVDWKDRNKAGDEKFPILNLSRDLSTLGAWVRLHYVYPYPHVRELIPLMADPANGLLPYLDIPFQHAHPDVLKRMARPAAASRTLDEIAAWRRDCPNITLRSTFIVGYPGETEAEFQTLLDWLDEAQLDRIGCFQYENVDGARSNALPDHVAPEVKQDRWDRFMEKAQAISEAKLQAKVGRTMQVLVDSVDEEGATCRTVADAPEIDGNLFIDEGFDGLTPGDLVTVEVDEASEYDLWGKLT
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_NEIMF
Sequence: MIAQEREARINGEITAKEVRLISESGEQLGVVSVREALAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_EHRCR
Sequence: MSDLLKEFNEQQMKLLSNKEIPKFSSGDTLRVSMKIFDGVSERLQVFEGVCIKRKNNGLHSSFTLRKISYNESIQLQVFLYSPIVESIEVIKFGRVRRAKLYYMLSLFGKSARIKERSDRTKKLS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HTPX_PSEPW
Sequence: MMRILLFVATNLAVVLVASITLSLFGFNGFMAANGVDLNLSSLLVFCAVFGFAGSLVSLFISKWMAKMSTGTQIISQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALVQGVVNTFVMFFARIIGNFVDKVIFKNEEGQGIAYYVATIVAELVLGILASMIVMWFSRRREYRADEAGAQLAGTAAMIGALQRLRVEQGLPVHMPDTMKAFGINGGLKHGLAGLLMSHPPLEERIEALRRRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSB6_SCHPO
Sequence: MSQSQFDPYVQNGGTTVAIAGDGFAILAGDTRSVNGYNINTRFQPRVHEVGDDLVIGASGFEADALALVKRIQQRIDLYHDNHERKMSAQSCACMVRTLLYGKRFFPYYVYTTVAGIDKEGKGEIYSFDPVGSYEREWCRAGGSAANFITPFLDNQVNLHNQYVPGSHGKERKPRRLLKLEEAMKITTDAFTSAGERHIEVGDSVLVKIITKEGVETRIIPLKKD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit beta type-6.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SFTPA_PIG
Sequence: MLRWPLALTFLLLAVSGLECDVKEVCLASPGIPGTPGSHGLPGRDGRDGIKGDPGPPGPMGPPGGMAGPPGQDGMIGAPGLPGERGEKGEPGERGPPGLPAHLDEELQSALHEIRHQILQSMGVLSFQEFMLAVGEKVFSTNGQSVAFWMSLESCVPEQVGRIAAPRSPEENEAIASIVKKHNTYAYLGLVEGPTAGDFFYLDGTPVNYTNWYPGEPRGRGKEKCVEMYTDGQWNDRNCQQYRLAICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
What are the official names of this protein?
Pulmonary surfactant-associated protein A, PSAP, PSP-A, SP-A.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: DNF1_LOCMI
Sequence: CLITNCPRG
What is the function of this protein?
Diuretic hormone.
What are the official names of this protein?
Locupressin, Diuretic neuropeptide F1/F2.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHD1_CHICK
Sequence: MNGHSDEESVRNSSGESRSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSESGSESGSQSESESDTSREKKQVQAKPPKADGSEFWKSSPSILAVQRSAVLKKQQQQQKAASSDSGSEEDSSSSEDSADDSSSETKKKKHKDEDWQMSGSGSVSGTGSDSESEEDGDKSSCEESESDYEPKNKVKSRKPPSRIKPKSGKKSTGQKKRQLDSSEEEEDDDEDYDKRGSRRQATVNVSYKEAEETKTDSDDLLEVCGEDVPQTEEDEFETIEKFMDSRIGRKGATGASTTIYAVEVDGDPNAGFEKSKELGEIQYLIKWKGWSHIHNTWETEETLKQQNVKGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECSWEDGALIAKKFQARIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHESLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWAPQMNAVVYLGDITSRNMIRTHEWMHPQTKRLKFNILLTTYEILLKDKSFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDDNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSTPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETRENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSRNWEEIIPESQRRRIEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSITERKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAVARDAELVDKSETDLRRLGELVHNGCIKALKDNSSGQERAGGRLGKVKGPTFRISGVQVNAKLVISHEEELAPLHKSIPSDPEERKRYVIPCHTKAAHFDIDWGKEDDSNLLVGIYEYGYGSWEMIKMDPDLSLTQKILPDDPDKKPQAKQLQTRADYLIKLLNKDLARKEAQRLAGAGNSKRRKTRNKKNKMKASKIKEEIKSDSSPQPSEKSDEDDDEEDNKVNEIKSENKEKSKKIPLLDTPVHITATSEPVPISEESEELDQKTFSVCKERMRPVKAALKQLDRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHAIKKRQESQQHNDQNISSNVNTHVIRNPDVERLKETTNHDDSSRDSYSSDRHLSQYHDHHKDRHQGDAYKKSDSRKRPYSAFSNGKDHRDWDHYKQDSRYYSDSKHRKLDDHRSRDHRSNLEGNLKDSRGHSDHRSHSDHRIHSDHRSTSEYSHHKSSRDYRYHSDWQMDHRASGSGPRSPLDQRSPYGSRSPLGHRSPFEHSSDHKSTPEHTWSSRKT
What is the function of this protein?
ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA.  Regulates polymerase II transcription.  Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step.  Regulates negatively DNA replication.  Not only involved in transcription-related chromatin remodeling, but also required to maintain a specific chromatin configuration across the genome.  Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity).  Required for centromeric localization of CENPA (PubMed:19625449).
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 1, CHD-1, ATP-dependent helicase CHD1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere.
Protein: PSBC_ILLOL
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVLKALYFGGVYDTWAPGGGDVRRITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWVGAICILGGTWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS17_ANOFW
Sequence: MSERNNRKVLVGRVVSDKMDKTITVLVETYKKHPLYGKRVKYSKKYKAHDENNVAKVGDIVKIMETRPLSATKRFRLVEVVEKAVIV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NUOD_CHESB
Sequence: MAETSIRNFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEYKTYLQAIPYFDRLDYVAPMNQEHAFALAIERLLGIDVPIRGQLIRVLYSEISRILNHLLNITTQAMDVGALTPPLWGFEEREKLMVFYERASGARMHAAYFRPGGVHQDLPEKLVEDIGKWIDPFLKTVDDLDELLTENRIFKQRNADIGIVSLEDAWAWGFSGVMVRGSGAAWDLRKSQPYECYPEMDFDIPVGKNGDCYDRYLIRMEEMRQSAKIMRQCVERLLGKERVGPVSNMDGKVVPPKRAAMKRSMESLIHHFKLYTEGYHVPAGEVYAAVEAPKGEFGVYLVADGTNKPYRCKLRAPGFAHLQAMDFMCRGHLLADVTAVLGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PTPB_STAAC
Sequence: MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.