PharMolix/UniProtQA huggingface dataset:
Protein: IBP5_RAT
Sequence: MVISVVLLLLAACAVPAQGLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYGEQTKIERDSREHEEPTTSEMAEETYSPKVFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRVIPAPEMRQESDQGPCRRHMEASLQEFKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHAFDSSNVE
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5.
What are the subcellular locations of this protein?
Secreted.
Protein: ACP_DECAR
Sequence: MDNIVERVKKIVAEQLGVNEADIKNESSFVDDLGADSLDTVELVMALEEEFECEIPDDQAEKITTVQQAVDYILAGKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_MYCTA
Sequence: MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVAEMHSRSGLIDEVKASTVDLATAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPTLDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRALADIHESIRELRFYRRTAFVPQPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGGL2_MAIZE
Sequence: MAPLLAAAMNHAAHPVLRSHLGPNNESFSRHHLSSSPQSSKRRFNLSFTPRSARVGNQNGVQLLSPSEIPRRDWFPSDFIFGAATSAYQIEGAWNEDGKGESNWDHFCHNFPERIMDGSNADIGANSYHMYKTDVRLLKEMGMDAYRFSISWPRILPKGTVEGGINQDGIDYYKRLINLLLENGIEPYVTIFHWDVPQALEEKYGGFLDKTQKRIVNDYKNFAKVCFDNFGDKVKNWLTFNEPQTFTSFSYGTGVFAPGRCSPGLDCAIPTGNSLVEPYIAGHNILLAHAEAVDLYNKYYKGENGRIGLAFDVMGRVPYGTSFLDEQAKERSMDINLGWFLEPVVRGDYPFSMRSLARERLPFFSDKQQEKLVGSYNMLGINYYTSIFSKHIDISPKYSPVLNTDDAYASQETYGPDGKPIGPPMGNPWIYLYPEGLKDILMIMKNKYGNPPIYITENGIGDVDTKEKPLPMEAALNDYKRLDYIQRHISTLKESIDLGANVHGYFAWSLLDNFEWYAGYTERYGIVYVDRKNNYTRYMKESAKWLKEFNTAKKPSKKIITPA
What is the function of this protein?
Beta-glucosidase acting poorly on artificial aryl beta-glucosides.  Has no activity toward the chromogenic substrate 6-bromo-2-naphthyl-beta-D-glucoside (6BNGlc).
What are the official names of this protein?
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 2, chloroplastic, Beta-glucosidase 2, ZmGlu2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYD_CLOBA
Sequence: MGEALNGLKRTMMCGEPREEHVGQKITLMGWVQRNRKLGGLDFIDLRDKTGIMQVVFGEEINAEAFEKAKGVRPEYCIAVTGEVVKRESVNENMPTGFVELKCQSLKILSESETPPIYIKENLDAAENIRLKYRYLDLRRPDMHRIFEIRSKTTKSIRDYLEKNDFLDVETPMLTKSTPEGARDYLVPSRNYPGMFYALPQSPQIFKQLLMVSGFDKYYQIVKCFRDEDLRANRQPEFTQVDMELSFVEQDDIMALNEGLIAHVFKEVAGVDVKLPIKRMTFKDAMEKYGSDKPDLRFGMEITNITEDVKDMDFVVFKSAIEAGGSVRALCLKGGAALGRKPLDKLGEFVKTYKAKGLAWIQLKEDGVKSSIAKFLTDDVTNSIIETMGAETGDAILIVADKESVVFQSLGALRLELAKQFELIKDKNEFNFTWITEFPLFEYSEEEERYTACHHPFTAPMEEDLDFLESAPGKVRSKAYDLVLNGEELGGGSIRIHDMELQQRMFKALGFTEEQAWERFGFLLQAFKFGPPPHGGLAFGLDRMIMFLAGTENIKDVIAFPKNQNAYCYLSEAPNIADEKQLTELGIGILPKQEKQEQE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_ANADE
Sequence: MEIRADEISRIIREQIKDYGKKVEVAETGSILSQADGVARIYGLAGAAAGELLEFPGGIRGLVLNLEEDNVGAAIMGPYEHIREGDPVKRTGLIAEVPVGEELLGRVVDGLGNPIDGRGPLNAKHQRKIEIKAPGIVKRKSVHEPMQTGLKAIDALVPIGRGQRELILGDRQTGKTAVAIDTILNNKGNNLYCFYVAIGQKQSTVARVVDTLKKHGAMEYTTVISASASDPAPMQYLAPYTGVTMAEYFRDSGRHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDKEGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFFQGVRPAINVGISVSRVGGSAQIKAMKQVAGSLKLDLAQYRELAAFAQFGSDLDKATQETLARGERLVELLKQGQYAPLSVEKQVIQIYAGTQKDAGGHNWIRSVPTEQVVRYMAELLEFLDARHPGIAKAIAEKKALDDGIRKDLDAALTEFAGIFKIEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL36_PSESM
Sequence: MKVRASVKKLCRNCKIIRREGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PAND_BACFN
Sequence: MMIEVLKSKIHCARVTEANLNYMGSITIDENLLDAANMIAGEKVYIADNNNGERFETYIIKGERGSGKICLNGAAARKVQPDDIVIIMSYALMDFEEAKSFKPTVIFPDPATNSVVK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_FRATW
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: HUTI_NEMVE
Sequence: MKNLIIRHARQVVLVCKNGERILKGEALKNIAILEGSVNRGISVVADEFGKIECIGYDDDVEPQYNQCSFASEIDATGMCVLPGLIDGHTHPVWVGDRVHEFAMKLAGASYMDVHKAGGGINFTVEHVHKATEDELYEPLKQRLNRMLQCGTTLVEAKSGYGLNTENEMKMLKVIERAKKELPIEISSTFCGAHAIPRGSTAKQAADNIINEQIPTLVKAIKAGELDVENIDVFCEKGVFEVEETRVILQAGKDAGLAINFHGDELHPIKGAELGAELGARAISHLEEISEEGIKAMSKSSVIGVLLPTTAYILRLKPPPARAMIDAGVAIALGTDFNPNAYCLSMPLTMHLACCILRMSMTEALAGATINAAASLGRADTHGSLEVGKFADMVVINAERWEHLIYQIGGHDDIIQHVVKHGKVVFSKR
What are the official names of this protein?
Probable imidazolonepropionase, Amidohydrolase domain-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
Protein: RL13_METMP
Sequence: MVVVNAENAVVGRLASYVAKLALSGEEITVVNAEKAIMTGNKEYIFQKYVQLRTRKSISNPKKMGPKYPRRPDDIVRRVIRGMLPYKKPRGVEAFKKIKIEVGVPEGVSIDINLGSAPNTIKYVTVGELSQFLGAKF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ARMX1_RAT
Sequence: MGRTREAGCVAAGMVIGAGACYCVYRLTWGKDENEKLWDDEDEEEEEEEESCSGKPEIGGKTVKERKTHVGVGAGAKPQDDSKSKAEANVGPENGPDVKKEVYPESHSEGGLEAKAKALFKSLKEQASAKAGRGIRFPNISRIRTLTSSLPCPGGRGGGCHPGRTGSRARNRTSGKVKRKNRSKSNKAPATAWPVRRGKFSFPYKIDDILSAPDLQKVLNILERTNDPFTQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTRDPIIREKTYNALNNLSVNSENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHYQHLLSYSFPDFFALLFLGNHFTKIQTMKLIINFTENPAMTRELVSCKVPSELISLFNKEWDREILLNILTLFENINDNIKSEGLASSRKEFSRSSLFFLFKESGVCVKKIKALASHKDLVVKVKVLKVLTKL
What is the function of this protein?
Regulates mitochondrial transport during axon regeneration.  Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool.  Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons.  Promotes neuronal survival and axon regeneration after nerve injury.  May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
What are the official names of this protein?
Armadillo repeat-containing X-linked protein 1.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single- pass membrane protein.
Protein: EFTU_VIBPA
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAICTTLAKVYGGEAKDFASIDNAPEERERGITIATSHVEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGGILVVAATDGPMPQTREHILLGRQVGIPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPVIQGSALGALNGEEQWEAKIVELAEALDTYIPEPERAVDQPFLMPIEDVFSIQGRGTVVTGRIERGILTVGDEVAIVGIKDTTTTTCTGVEMFRKLLDEGRAGENVGALLRGTKRDEVERGQVLAKPGSITPHTKFESEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGDISLPEGVEMVMPGDNIQMVVELIAPIAMDEGLRFAIREGGRTVGAGVVAKIFE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STAA3
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TOFU6_CAEBR
Sequence: MASSSTAFYLKDAGFHIRNVPKEWNDWNLFHIFQVFGRVGYCRVAGQSNDMQLGFVNMLSAADAEEVRKNLHDGNLIGDNYSLKVSDHKNIGGALLPMASISVQKLLSSPPAKSGPVHLSSSWLPLNKDIEVEVVDYLPSSSAAKDVFALTILRINDAQSNEKYNAMHEKMNSYAQLVAFDSELQIGYDGVFRESPRSIKRVRRISATKLYLVDFGKIINYEKSKCFQIPKVFQTIPTRVSFCGLDGLTWSEQAIPSFDNIREVVQKWGAMENATLHAVTCGFAGAINMINLFCGNSVLAERLQRKGICEYLPRHQQPRFAYSRDSLLKHTNAGVTAHISNDADVVKDLLKKIDGVKSMLRELDL
What is the function of this protein?
Required maternally for early embryonic cell divisions.  May have a role in DNA replication.
What are the official names of this protein?
Embryonic developmental protein tofu-6, 21U-RNA biogenesis fouled up protein 6, Maternal effect lethal protein 47.
Protein: PEG3_PANTR
Sequence: MLPPKHLSATKPKKSWAPNLYELDSDLTKEPDVIIGEGPTDSEFFHQRFRNLIYVEFVGPRKTLIKLRNLCLDWLQPETHTKEEIIELLVLEQYLTIIPEKLKPWVRAKKPENCEKLVTLLENYKEMYQPEDDNNSDVTSDDDMTRNRRESSPPHSVHSFSGDRDWDRRGRSRDMEPRDRWSHTRNPRSRMPQRDLSLPVVAKTSFEMDRDDDRDSRAYESRSQDAESYQNVVDLAEDRKPHNTIQDNMENYRKLLSLGVQLAEDDGHSHMTQGHSSRSKRSAYPSTSRGLKTMPEAKKSTHRRGICEDESSHGVIMEKFIKDVSRSSKSGRARESSDRSQRFPRMSDDNWKDISLNKRESVIQQRVYEGNAFRGGFRFNSTLVSRKRVLERKRRYHFDTDGKGSIHDQKACPRKKPFECGSEMRKAMSMSSLSSLSSPSFTESQPIDFGAMPYVCDECGRSFSVISEFVEHQIMHTRENLYEYGESFIHSVAVSEVQKSQVGGKRFECKDCGETFNKSAALAEHRKIHARGYLVECKNQECEEAFMPSPTFSELQKIYGKDKFYECRVCKETFLHSSALIEHQKIHFGDDKDNEREHERERERGETFRPSPALNEFQKMYGKEKMYECKVCGETFLHSSSLKEHQKIHTRGNPFENKGKVCEETFIPGQSLKKRQKTYNKEKLYDFTDGRDAFMQSSELSEHQKIHSRKNLFEGRGYEKSVIHSGPFTESQKSHTITRPLESDEDEKAFTISSNPYENQKIPTKENVYEAKSYERSVIHSLASVEAQKSHSVAGPSKPKVMAESTIQSFDAINHQRVRAGGNTSEGREYSRSVIHSLVASKPPRSHNGNELVESNEKGESSIYISDLNDKRQKIPARENPCEGGSKNRNYEDSVIQSVSRAKPQKSVPGEGSGEFKKDGEFSVPSSNVREYQKARAKKKYIEHRSNETSVIHSLPFGEQTFRPRGMLYECQECGECFAHSSDLTEHQKIHEREKPSGSRNYEWSVIRSLAPTDPQTSYAQEQYAKEQAWNKCKEFRQFFATSEDLNTNQKIYDQEKSHGEESQGENTDGEETHSEETHGQETIEDPVIQGSDMEDPQKDDPDDKIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYECPKCGESFIHSSFLFEHQRIHEQDQLYSMKGCDDGFIALLPMKPRRNRAAERNPALAGSAIRCLLCGQGFIHSSALNEHMRLHREDDLLEQSQMAEEAIIPGLALTEFQRSQTEERLFECAVCGESFINPAELADHVTVHKNEPYEYGSSYTHTSFLTEPLKGAIPFYECKDCGKSFIHSTVLTKHKELHLEEEEEDEAAAAAAAAAQEVEANVHVPQVVLRIQGSNVEAAEPEVEAAEPEVEAAEPEVEAAEPNGEAEGPDGEAAEPIGEAGQPNGEAEQPNGDADEPDGAGIEDPEERAEEPEGKAEEPEGDADEPDGVGIEDPEEGEDQEIQVEEPYYDCHECTETFTSSTAFGEHLKTHASMIIFEPANAFGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG
What is the function of this protein?
Induces apoptosis in cooperation with SIAH1A.  Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage.  Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity).
What are the official names of this protein?
Paternally-expressed gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: POLS_RRVT
Sequence: MNYIPTQTFYGRRWRPRPAFRPWQVSMQPTPTMVTPMLQAPDLQAQQMQQLISAVSALTTKQNVKAPKGQRQKKQQKPKEKKENQKKKPTQKKKQQQKPKPQAKKKKPGRRERMCMKIENDCIFEVKLDGKVTGYACLVGDKVMKPAHVKGTIDNPDLAKLTYKKSSKYDLECAQIPVHMKSDASKYTHEKPEGHYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTALSVVTWTKDMVTRVTPEGTEEWSAALMMCILANTSFPCSSPPCYPCCYEKQPEQTLRMLEDNVNRPGYYELLEASMTCRNRSRHRRSVTEHFNVYKATRPYLAYCADCGDGYFCYSPVAIEKIRDEAPDGMLKIQVSAQIGLDKAGTHAHTKIRYMAGHDVQESKRDSLRVYTSAACSIHGTMGHFIVAHCPPGDYLKVSFEDADSHVKACKVQYKHDPLPVGREKFVVRPHFGVELPCTSYQLTTAPTDEEIDMHTPPDIPDRTLLSQTAGNVKITAGGRTIRYNCTCGRDNVGTTSTDKTINTCKIDQCHAAVTSHDKWQFTSPFVPRADQTARRGKVHVPFPLTNVTCRVPLARAPDVTYGKKEVTLRLHPDHPTLFSYRSLGAEPHPYEEWVDKFSERIIPVTEEGIEYQWGNNPPVRLWAQLTTEGKPHGWPHEIIQYYYGLYPAATIAAVSGASLMALLTLAATCCMLATARRKCLTPYALTPGAVVPLTLGLLCCAPRANAASFAETMAYLWDENKTLFWMEFAAPAAALALLACCIKSLICCCKPFSFLVLLSLGASAKAYEHTATIPNVVGFPYKAHIERNGFSPMTLQLEVVETSWEPTLNLEYITCEYKTVVPSPFIKCCGTSECSSKEQPDYQCKVYTGVYPFMWGGAYCFCDSENTQLSEAYVDRSDVCKHDHASAYKAHTASLKATIRISYGTINQTTEAFVNGEHAVNVGGSKFIFGPISTAWSPFDNKIVVYKDDVYNQDFPPYGSGQPGRFGDIQSRTVESKDLYANTALKLSRPSPGVVHVPYTPTPSGFKYWLKEKGSSLNTKAPFGCKIKTNPVRAMDCAVGSIPVSMDIPDSAFTRVVDAPAVTDLSCQVVVCTHSSDFGGVATLSYKTDKPGKCAVHSHSNVATLQEATVDVKEDGKVTVHFSTASASPAFKVSVCDAKTTCTAACEPPKDHIVPYGASHNNQVFPDMSGTAMTWVQRLASGLGGLALIAVVVLVLVTCITMRR
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: GPDA_MOUSE
Sequence: MAGKKVCIVGSGNWGSAIAKIVGSNAGRLAHFDPRVTMWVFEEDIGGRKLTEIINTQHENVKYLPGHKLPPNVVAIPDVVQAATGADILVFVVPHQFIGKICDQLKGHLKANTIGISLIKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVAEEKFCETTIGCKDPAQGQLLKDLMQTPNFRITVVQEVDTVEICGALKNIVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGTVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKEMLNGQKLQGPQTARELHSILQHKGLVDKFPLFTAVYKVCYEGQPVGEFIRCLQNHPEHM
What is the function of this protein?
Has glycerol-3-phosphate dehydrogenase activity.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic, GPD-C, GPDH-C.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_JANMA
Sequence: MNNIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMEAQVLDSMDIERERGITIKAQTAALMYKARDGQVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVEVVPVLNKIDLPSADPANAIAEIEEVIGIDASEAVHCSAKTGLGVQDVLESLITKVPPPKGDATAPLQALIVDSWFDNYVGVVMLVRVMNGTLRPKDKILLMASESQHLVESVGVFTPKSISRDTLTAGQVGFIIAGIKELKAAKVGDTVTLASRPAAEPLPGFKEVQPQVFAGLFPVEANQYDALRDSLEKLKLNDAALMYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVIYEVVLRDGSILMVDNPSKMPDPSKIEEIREPIVTVNLYMPQEYVGSVITLCTQKRGIQMDMSYHGKQVKLIYEMPMAEIVLDFFDKLKSTSRGYASMDYEFKEYRSSDVVKVDMLINSEKVDALAIIVHRANSQYRGRAVAAKMRELIPRQMFDVAIQAAIGANIISRENVKALRKNVLAKCYGGDISRKRKLLEKQKAGKKRMKQVGSVEIPQEAFLAILQVDDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARGR_SHISS
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_YERPP
Sequence: MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKDLPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCYVGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAVDNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQNLAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR2_YEAST
Sequence: MNLLRMNALTSKARSIERLKQTLNILSIRNHRQFSTIQQGSKYTLGFKKYLTLLNGEVGSFFHDVPLDLNEHEKTVNMIVEVPRWTTGKFEISKELRFNPIVQDTKNGKLRFVNNIFPYHGYIHNYGAIPQTWEDPTIEHKLGKCDVALKGDNDPLDCCEIGSDVLEMGSIKKVKVLGSLALIDDGELDWKVIVIDVNDPLSSKIDDLEKIEEYFPGILDTTREWFRKYKVPAGKPLNSFAFHEQYQNSNKTIQTIKKCHNSWKNLISGSLQEKYDNLPNTERAGNGVTLEDSVKPPSQIPPEVQKWYYV
What is the function of this protein?
Involved in energy production.  Its activity is stimulated by uncouplers of ATP synthesis.
What are the official names of this protein?
Inorganic pyrophosphatase, mitochondrial, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GME2_ORYSJ
Sequence: MALNEEYTYVELEKEPYWPFEKLRISITGAGGFIASHIARRLKSEGHYIIASDWKKNEHMTEDMFCHEFHLVDLRVMDNCLKVTTGVDHVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMLEAARINGVKRFFYASSACIYPEFKQLDTVVSLKESDAWPAEPQDAYGLEKLATEELCKHYTKDFGIECRVGRFHNIYGPFGTWKGGREKAPAAFCRKALTSTDRFEMWGDGLQTRSFTFIDECVEGVLRLTKSDFREPVNIGSDEMVSMNEMAEIVLSFENKQLPIHHIPGPEGVRGRNSDNTLIKEKLGWAPTMRLKDGLRITYFWIKEQLEKEKAEGVDLSAYGSSKVVQTQAPVQLGSLRAADGKE
What is the function of this protein?
Catalyzes a reversible epimerization of GDP-D-mannose that precedes the committed step in the biosynthesis of vitamin C (L-ascorbate), resulting in the hydrolysis of the highly energetic glycosyl-pyrophosphoryl linkage.  Able to catalyze 2 distinct epimerization reactions and can release both GDP-L-galactose and GDP-L-gulose from GDP-mannose.
What are the official names of this protein?
GDP-mannose 3,5-epimerase 2, GDP-Man 3,5-epimerase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: TGT_VIBC3
Sequence: MKLKFELKKKNGNARRGQLIFERGTVQTPAFMPVGTYGTVKGMTPEEVKETGAQILLGNTFHLWLRPGQEVMKMHGDLHDFMNWQGPILTDSGGFQVFSLGDIRKITEEGVHFRNPVNGDKIFMDAEKSMEIQKDLGSDIVMIFDECTPYPATHDEAKKSMEMSLRWAKRSRDHFDKLENPNNLFGIVQGGVYEDLRDVSVKGLTEIGFDGYAVGGLAVGEPKEDMHRVLEHTCPQLPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTGGVIKIRNAAHKTDTTPLDLHCDCYTCKNYSKSYLHHLDRCNEILGARLNTIHNLRYYQRLMESIRKAIDEDRFDQFVAEFYARRNREVPPLQKDKA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CLPX_TREPA
Sequence: MLRSKGDLVLGCSFCGKKEDERRRIVTGHGVSICNYCVERCAEYLRDRKPSALALMTKEEIPTPLELKAYLDQYVIGQDLAKRVLSVAVYNHYKRVAGRSLDIDSVLIEKSNVLLIGPTGSGKTLLAKTLSQKMKVPFAIADATTLTEAGYVGEDVENILLKLVQNANGDVALAERGIIFIDEIDKISRKSENVSITRDVSGEGVQQALLKIIEGTIASVPPQGGRKHPNQDMLRVDTSNILFICGGAFVGLDGIVGTRVCKNPVGFGADVKTVKERGLQLMHEDVIPDDLVKFGLIPEIIGRLPVTVALDALSKEDLRNILVRPRNAIVRQFEALFALDDVRLVFDEDALDAIAQQAIDQKTGARGLRSIVERLMLDAMFEAPSLKGKKELCITKKVVTQEEKASVRLVSERTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.