PharMolix/UniProtQA huggingface dataset:
Protein: LMBD1_NEMVE
Sequence: MTIPHEVLAQGWIPFTVVVVLAILFSWFYIRYYQDHSQSEVSSTITGIIALFIALMTTALVPVDIFLVSYMKNDDGSWKPWSANRMNRDDIEETAVATTYYILYALLAFFVFVIIPFMYFFFEERDEDITTAERACGALKYSIGFLIVASVLLLVGAFAPLKQPPKNVTEWDKRLIFLKDELKSNNGETALSLLIGFLTLIGMLIMITYTAYGMTALPFSLLKGFKSAKTEQESVTRRRSRNQEQARLIKAQYMGGRAMSSRDRRRLSELEKEEHALATRERRLEAAQLGWLNKCLKLLRPFEMVFGAFFLLVALLIFVSLFITCLDKALHSNGYQYGYSLPTPQLPNPINIIMVYAQIVFPLDYCLFLLVVLYFVYSSMAGIRRVGIRCCWIKLFKVRPRRTLPQALLFMCVMLMLIVLSLNVMLFSLAPQYVMYGSQNYRANSTVTSLVNHTGIIQNVTTSHGIAKVCSMEMSSDHCTMTRIAVFLNRFFYKVWFFGACYYWGTWLFLVVFMTGLIYSIVRKRKTVVDEEYDSSDDSDEEMVTA
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: EFTU_CHLT3
Sequence: MAKESYKREKPHVNIGTIGHVDHGKTTLTAAITKVLSEKGQAQKMDFDEIDKAPEEKERGITISTSHVEYETPSRHYAHIDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLAKQVNVPSIVVFMNKVDIADPELIELVEMELRELLSSYGFPGDDIPIIQGSALGALNGEAEWVGKIEELMEAVDNYIPTPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGVIKINEEVELVGIRPTKKSVVTGIEMFRKLLDQGEAGDNAGLLLRGVNKDELERGMVIAKPGSITPHTKFKAEVYILKKEEGGRHTPFFNGYRPQFYFRTTDVTGSVNLPDGVEMVMPGDNLSIEAELIAPIAMDEGLRFAIREGGRTVGAGTVTSIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_CROS8
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTVSEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPVVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFRDIIKNVGVAIIGQTNSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYALSEELAQAIVGVANGAGVRTTALLTDMNEVLASSAGNAVEVREAVRFLTGDYRNPRLLEVTMALCVEMLLSGGLAKDETEARAKLQQVLDNGQAAEIFGRMVAAQSGPADFVDNYERYLPAATLSKAVYADRSGFVTQMDTRALGMAVVAMGGGRRQASDSIDYSVGLTDMARLGEQVDGERPLAIIHAKSEASWQEAAAAVKAAINVDDTAAKTSPVVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: SSRP_FRAAA
Sequence: MPKETGRKSIAQNKRARHDYDILDTYEAGLVLRGTEVKALRAGRASLVDGFAQVSDGEIWLHNVHIPEYTEGTWTNHAPRRKRKMLLHRAEIEKLIGQTQEGGLTLVPLALYWKDGRAKIEIALARGRKSYDKRHALAERDAAREISREMGRRVKGRYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FIS_SHEPW
Sequence: MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RECX_STAAN
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ECOUT
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CYSKP_SPIOL
Sequence: MASLVNNAYAALRTSKLELREVKNLANFRVGPPSSLSCNNFKKVSSSPITCKAVSLSPPSTIEGLNIAEDVSQLIGKTPMVYLNNVSKGSVANIAAKLESMEPCCSVKDRIGYSMIDDAEQKGVITPGKTTLVEPTSGNTGIGLAFIAAARGYKITLTMPASMSMERRVILKAFGAELVLTDPAKGMKGAVEKAEEILKKTPDSYMLQQFDNPANPKIHYETTGPEIWEDTKGKVDIFVAGIGTGGTISGVGRYLKERNPGVQVIGIEPTESNILSGGKPGPHKIQGLGAGFVPSNLDLGVMDEVIEVSSEEAVEMAKQLAMKEGLLVGISSGAAAAAAVRIGKRPENAGKLIAVVFPSFGERYLSSILFQSIREECENMKPE
What are the official names of this protein?
Cysteine synthase, chloroplastic/chromoplastic, CSase B, CS-B, O-acetylserine (thiol)-lyase, O-acetylserine sulfhydrylase, OAS-TL B.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chromoplast.
Protein: ADRB1_BOVIN
Sequence: MGAGVLALGASEPCNLSSAAPVPDGAATAARLLVPASPPASLLTSASEGPPLPSQQWTAGMGLLMAFIVLLIVVGNVLVLVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVCTVWAISALVSFLPIFMQWWGDKDAKASRCYNDPECCDFIINEGYAITSSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLSGPARLPSPAPSPGPPLPAATVANGRANKRRPPRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACGSHAAAGDPPRALGCLAVARPSPSPGAASDDDDDDDEDDVGAAPPVRLLEPWAGYNGGAAANSDSSPDEPSRAGCASESKV
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  This receptor binds epinephrine and norepinephrine with approximately equal affinity.  Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity).  Involved in the regulation of sleep/wake behaviors (By similarity).
What are the official names of this protein?
Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity).
Protein: RL33_YERPS
Sequence: MAKGVREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: G39AC_DROME
Sequence: MKRNAFEELRVQLRTLKWLGVLRFTIDFNKCLVRENASEERSAWLYLIGVVGITCSLIVYSTYFPSHFIMGKHNTTGNCYALINIRSCSIVTMLIYTQLYIQRFRFVALLQSILRFNQISGSHREEGRFAFYYYTHLSLLIICMLNYAYGYWTAGVRLTTIPIYLLQYGFSYLFLGQVVVLFACIQQILLSILKYYNQVVLKNIKSSKESREFYYNFCKYNQVIWLSYTEINHCFGLLLLLVTGLILLITPSGPFYLVSTIFEGRFRQNWQFSLMSFTAILWSLPWIVLLVLAMGRNDVQKEANKTAKMLTKVPRTGTGLDRMIEKFLLKNLRQKPILTAYGFFALDKSTLFKLFTAIFTYMVILVQFKEMENSTKSINKF
What is the function of this protein?
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.  Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone.
What are the official names of this protein?
Gustatory and pheromone receptor 39a, isoform D.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLU_HAEI8
Sequence: MSEMTPREIVSELDQHIIGQADAKRAVAIALRNRWRRMQLQEPLRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAMKLVRQQEIAKNRARAEDAAEERILDALLPPAKNQWGEVENHDSHSSTRQAFRKKLREGQLDDKEIEIDVSAGVSMGVEIMAPPGMEEMTNQLQSLFQNLGSDKTKKRKMKIKDALKTLIDDEAAKLINPEELKQKAIDAVEQNGIVFIDEIDKICKKGEYSGADVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQVARPSDLIPELQGRLPIRVELTALSAADFERILTEPHASLTEQYKALMATEGVNIEFTTEAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASDMNGQTVNIDAAYVADALGEVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC_STAAN
Sequence: MEFREQVLNLLAEVAENDIVKENPDVEIFEEGIIDSFQTVGLLLEIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS27_ASHGO
Sequence: MNTEIQTVAALGECIQRATSESIPNGEIDLALALDVSDAVRSRRLGARDSMRALKKRVLQTKSNPNTQLAAWRLVEVCVKNGGTHFLKEVCSREFMDCMEHVAAQEKTVDNEDLVQLCRRIIFELYTAFKNDSQLSYVSQVHQRLQARGVEFPQAAPGYLVNTMAMFDSKAPADWVDSDACMICSNAFTFLNRKHHCRSCGGIFCNEHSSHQLPLPEMGITEPVRVCDNCYDEYEIKKHSSRRLRRQSQRRARPKAEREDEDDDLRRAIELSLRESKTQDNLVPTVTRLENSDATKDDEDPEFLAAVQASLREHQLEQERQAAAAAAAAKHPSQPERAVQLPSLMDSRQAPVAQQRYSTLTNQEEDDIYLFANLVEKMKGQPMNAVLEDTQLQMLYQKVLGTRPRLNHSLNDTFHKYNTLVDMNAKISDIMSIYDTMLERQLRNINLSQQYSMPHLPSDPYTYQMHRQPESSPANTVPYEKTQPEPTYRSYARSSSNAAELTPAILHTTQSSPMENRQSQSVTGFEPQVSEPDIKKTLLSSPSEPLYPPEESIPDKEKEAQVPITQFEFPSVPAQKIKMATPQNERVTEDAGTTPQEETLLIEL
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CRVP_PROFL
Sequence: MIAFIVLPILAAVLQQSSGNVDFDSESPRKPEIQNEIIDLHNSLRRSVNPTASNMLKMEWYPEAAANAERWAYRCIESHSSRDSRVIGGIKCGENIYMATYPAKWTDIIHAWHGEYKDFKYGVGAVPSDAVIGHYTQIVWYKSYRAGCAAAYCPSSKYSYFYVCQYCPAGNIIGKTATPYKSGPPCGDCPSDCDNGLCTNPCTRENEFTNCDSLVQKSSCQDNYMKSKCPASCFCQNKII
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization (PubMed:12047379).  May target voltage-gated calcium channels (Cav) on smooth muscle.
What are the official names of this protein?
Cysteine-rich venom protein triflin, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: DHQS_CENSY
Sequence: MPRAQLQRFLSGISAEGIRTVYLDPKDAAKAKLDAMHSSPSSRYVVLEGRAAKPRGKKVGRRFKILSNKDIDGVLQEAQKGLDFVITEVQDWKIIPLENMIAKLHKIHTRLYAVARSPAEVRKMFSILDVGVDGVIFTASTVGDVREALVHLGTKSFRLQPARITEIREVGDGERVCVDTASMLERGEGMLVGSRSNFMFLVHNESVGSSFTSPRPFRVNAGAVHSYTLGTDGNTLYLSEVETGTEVLVLDSHGRARRAAVGRSKIERRPMLMIKAEADGEIGGIIAQDAETIRFVRPGGGLVSVTHLKKGDKVLVHSKPAAGRHFGMEVADEYILEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: MAO1_SHESH
Sequence: MDDHKRPLYLPFAGPAILEAPLINKGSAFTDEERVFFNLEGLLPHVIETIEEQASRAYDQYTNFTNDLDKHIYLRNIQDTNETLYYRLVQNHITEMMPIIYTPTVGMACERFSKNYRRNRGLFISYPNKDRIDDLLNNSTRQKVKIIVVTDGERILGLGDQGIGGMGIPIGKLSLYTSCGGISPAYTLPITLDVGTDNPNLLEDPMYMGWRHQRIGGEEYTEFVEAFMQAVHRRWPDALIQFEDFAQKNAMPLLERYKDQYCCFNDDVQGTAAVTVGSLLAACKAAKTKLSEQRVTFLGAGSAGCGIAEAIVAQMIAEGLSEEQARAQVFMVDRWGLLQDNMPTLLPFQQKLAQKCDDIEGWDNFSENISLLDVVNNAKPTVLIGVSGAPGVFSEEIIKAMHSHCPRPIVFPLSNPTSRVEATPKDLLHWTKGQALVATGSPFEPVVVEDETFEIAQCNNSYIFPGIGLGVLAAGAKRVSNEMLMASSRALAECSPLALDGEGPLLPPLEEIHKVSKHIALAVGKVAIEQGHALPCTDELLEQSIEDNFWTAEYRRYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: SPAT9_MOUSE
Sequence: MEVRPIGWICGQVVKNFSGRLEGLQKAIMDLIDEFKDDLPTILRLSQSSQKTDPVQKTSKVRMALALAKINRGTLIQGLNHISSSSKSVAKLLQPRLAYRLLELRSISHRLLREVNVASQPLHSVQMKRGSLFEIISFPAKTALTSIMYASYAALIYLAVCVNAVLAKIKKIFQEEESIRQNRESENFRKAFSEPALRKPMFSESEIKAKPYRSLPEKPDNLLDQPKPPANKQSNKIQVLHSVFDQLAELNE
What is the function of this protein?
May play at role in testicular development/spermatogenesis and may be an important factor in male infertility.
What are the official names of this protein?
Spermatogenesis-associated protein 9.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATP6_YERE8
Sequence: MSASGEISTPRDYIGHHLNNLQLDLRTFELVNPHSPGPATFWTLNIDSLFFSVVLGLAFLFVFRKVAAGATSGVPGKLQTAVELIIGFVDNSVRDMYHGKSKVIAPLALTVFVWVLLMNMMDLLPIDLLPYIGEHVFGLPALRVVPTADVSITLSMALGVFILILFYSIKMKGVGGFVKELTMQPFNHPIFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWMLSLPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDI_ECO81
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANRDVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: HIS6_SALPA
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETLDWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAEA_EMENI
Sequence: MFEMGPVGTRLPAMTSPAHNHYSYHSPTSSDRGRSRQNSDAMDIQSITEREPATRYAVAGGPAPWNRNGSPSMSPMYSNNSERNQFHEENGRTYHGFRRGMYFLPCDEQEQDRLDIFHKLFTVARVSESLIYAPHPTNGRFLDLGCGTGIWAIEVANKYPDAFVAGVDLAPIQPPNHPKNCEFYAPFDFEAPWAMGEDSWDLIHLQMGCGSVMGWPNLYRRIFAHLRPGAWFEQVEIDFEPRCDDRSLDGTALRHWYDCLKQATAETMRPIAHSSRDTIKDLQDAGFTEIDHQIVGLPLNPWHQDEHERKVARWYNLAVSESIENLSLAPFSRVYRWPLERIQQLAADVKSEAFNKEIHAYNILHIYQARKPLR
What is the function of this protein?
Methyltransferase that performs automethylation at Met-207 (PubMed:23532849).  No other methyl-accepting substrate has been identified yet (PubMed:23532849).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:15075281, PubMed:20132440).  Controls the expression of the sterigmatocystin, penicillin, and lovastatin gene clusters (PubMed:15075281, PubMed:16968230).  Controls light-dependent formation of the velB-vosA complex, veA protein modification, and is required for light-mediated inhibition of sexual development (PubMed:21152013).  Within the velvet complex, controls light-dependent secondary metabolism (PubMed:18556559).  Involved in the defense response against Drosophila melanogaster larval grazing (PubMed:24023705).
What are the official names of this protein?
Protein-methionine methyltransferase laeA, Secondary metabolism regulator laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CREL1_RAT
Sequence: MAPQPLRGLVPFLLWCLSLFLSLPGPVWLQPSPPPHSAPRAEPHPCHTCRALVDSFNKGLERTIRDNFGGGNTAWEEEKLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVEAWWFHRQQEAPDLFQWLCSDSLKLCCPSGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNSSHLVCSACFGPCARCTGPEESHCLQCRKGWALHHLKCVDIDECGTEQATCGAAQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSRGYQQVGSKCLDVDECETVVCPGENEQCENTEGSYRCVCAEGFRQEDGICVKEQIPESAGFFAEMTEDEMVVLQQMFFGVIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
What is the function of this protein?
Protein disulfide isomerase (By similarity).  Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane (By similarity).
What are the official names of this protein?
Protein disulfide isomerase Creld1, Cysteine-rich with EGF-like domain protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRELD family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PGK_ACTP7
Sequence: MSVIKMADLDLAGKRLFIRADLNVPVKDGKVTSDARIRATIPTLKLALQKGAKVMVTSHLGRPTEGVFEEANSLQPVVDYLNASDLGVPVRLVRDYLDGVEVAENEIVVLENVRINKGEKKNDPELAKKYAALCDVFVMDAFGTAHRAEGSTYGVAEYAPVACAGPLLAAELDALGKALKEPQRPMLAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAEGHPVGKSLYEADLIPEAKRLAAATNIPVPVDVRVGTEFSEIAPATEKAVSEVQADESIFDIGDKSAEELANIIKSAKTILWNGPVGVFEFPNFRKGTEVISNAIAEATANGAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVEILEKRANG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_METFK
Sequence: MLIIPAIDLKDGHCVRLKQGLMEDATVFSEDPGAMARHWVDQGGKRLHLVDLNGAFAGKPVNEGAIKAIVKAVGNDIPIQLGGGIRDLDTIERYLDDGISYVIVGTAAVKSPGFLHEACYAFPGQIMVGLDAKDGKVAVDGWSKLTGHDVIDLAKKFEDYGVEAVVYTDIGRDGMLTGVNIEATVALAQALTIPVIASGGVTNLDDVRRLAEVESEGIIGAITGRAIYEGTLNFTEAQALADELSQI
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2760_CUPPJ
Sequence: MPSFDVVCEANMVEVKNAVEQANKEISTRFDFKGSDARVEQKEGELTAFADDDFKLGQVKDVLLNKMAKRNVDVRFLDYGKVEKISGDKVKQVITIKKGVTGDLGKKIVRMIKDSKIKVQGSIQGDAVRVSGTKRDDLQSVIAMLRKDVSEAPLDFNNFRD
What are the official names of this protein?
UPF0234 protein Reut_A2760.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: HTF_BANRO
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, BanRo-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRC_HALWD
Sequence: MKQRELRERAAELPAEPGVYQFLEDNTVRYVGKALELRDRVRSYADPRSERIRQMVARADDIDIALTETETQALLLEANLIKRHQPRYNVRLKDDKSYPLVQFTNHSVPRIEVTRDPDSDATVFGPYTEVKRLETAVKALREVYGLRGCSDHKYNNRNRPCLEYEVGLCSAPCTGEIDATAYRSAVESAVQFFEGKTGILADPLRQEMQAAATAEEFERAANIRDRLAVIESFHGGGEAAVSSEDNSHTAETTSERAVDVLGVAIEGTTATVARLHSDNGQLVDRSQHRLNAPTGEDRASAVLTAFLTQYYAERSLPDAILCSEHPHDNDVREWLSVEGVNIRVPGTGRESKLIDLALKNARNGSVHDNESAALADALGFSIINRIEGFDVSHSQGRAVVGSNVCFIDGSAATDAYRRKRLTDTNDDYARMQELLTWRAKRACDGRDERPDPDLIVIDGGKGQLRAAREAVETTGWDVSTIALAKADELVVTPNGVHDWDADAPQLHLLQRVRDEAHRFAVQYHQSIRDDIHTVLSDVPGVGEQTQQALLRRFGSVENVRSASRDALCDVPGVGKQTADTIANRL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.