PharMolix/UniProtQA huggingface dataset:
Protein: GT4_ORYSI
Sequence: MSKLQDRHGGEAAADVGRRARHQRLLLSFPVFPIVLLLLAPCTIFFFTSGDVPLPRIRIEYARRDAPTITAVAADTSPPPPSPPSSSPPPLSFPPPPPPPSSPPPPALPVVDDHSDTQRSLRRLRQLTDSPYTLGPAVTGYDARRAEWLRDHTEFPASVGRGRPRVLMVTGSAPRRCKDPEGDHLLLRALKNKVDYCRVHGFDIFYSNTVLDAEMSGFWTKLPLLRALMLAHPETELLWWVDSDVVFTDMLFEPPWGRYRRHNLVIHGWDGAVYGAKTWLGLNAGSFIIRNCQWSLDLLDAWAPMGPPGPVRDMYGKIFAETLTNRPPYEADDQSALVFLLVTQRHRWGAKVFLENSYNLHGFWADIVDRYEEMRRQWRHPGLGDDRWPLITHFVGCKPCGGDDASYDGERCRRGMDRAFNFADDQILELYGFAHESLDTMAVRRVRNDTGRPLDADNQELGRLLHPTFKARKKKTSRAARPM
What is the function of this protein?
Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
What are the official names of this protein?
Probable glycosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: NUON_XANC5
Sequence: MMTTPTLAPLTTADLAPLVPELVLIGGAFALLMLDLFVSQRNKVWTHLFSVAVLAVVLVLLATGTGGQGDIFNGMFVRDTAADVMKTVIVLVSGLSLVYGWTYLRERNLYQGEIPVLVLFATAGMMLLASAGSLLMVYLGLELLALCSYALVASNRDNGLATEAAMKYFVLGSLASGLLLYGMSLVYGATGTLSLAGIHDAIEGSNERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQGAPAPIALFISSAPKLAAFGMAYRLLEVGMGPLSPQWHLLIGGLSAVSLVVGNLMAIAQSNLKRMLAYSTVSHIGFLLMGVAGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRNGFEAENIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLAVLGAAVKGDMLWLALVGVICAVIGAYYYLRVIKVMYFDEPVGEPLPANNDRVLGTVLGVNALALLALGLAWSPIMVWCQRAFAGLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LBD22_ARATH
Sequence: MPSGKPSSVFPLHPKPTPLKPSSSTSSSNNNSTNQACAACKYQRRKCAPDCLLAPYFPHDRHRQFLNAHKLFGVSNITKIIKSLTPPEKDAAMHTIMFQSDARANDPVDGCYGIIKKLQYQIEYTRNELEIVLQQLAMFRDRAHQHHHQEPHIQMQEQEDLSSFSSSCDLNNNNSIPYNYPLNHIQEPNQQQYCSSGNNFSGLQEDMWCLQLQDSSTIVNMKAGFIDECEDVKPVEEVSSERHEFEPHEAFVEQRKLDLPSAQYIISS
What are the official names of this protein?
LOB domain-containing protein 22, ASYMMETRIC LEAVES 2-like protein 30, AS2-like protein 30.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: VF317_ASFK5
Sequence: MVETQMDKLGFLLNHIGKQITTKVLSNAHITQNMKEIILEKDSVDGGAAKNVSKGKSSPKEKKHWTEFESWEQLSKSKRSFKEYWAERNEIVNTLLLNWDNVRGALKKFLNDDREWCGRINMINGVPEIVEIIPSPYKAGENIYFGSEAMIPAEIYSRVANKPAMFVFHTHPNLGSCCGGMPSICDISTTLRYLLMGWTAGHLIISSNQVGMLTVDKRIIIDLWANENPRWLMAQKILDIFMMLTSRRSLVHPWTLRDLKKILQDYGIEYIIFPSNDFFIYEDERLLMFSKKWTNFFTLHELLDDLETIETKASST
What are the official names of this protein?
Uncharacterized protein F317L, pF317L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus F317L family.
What are the subcellular locations of this protein?
Virion.
Protein: RAPE_BACSU
Sequence: MISITSAEVGMKINEWHRHIQKFNVTDAEMLKAEIERDIEVMEEDQDLLIYYQLMAFRHKIMLEYTLPSDENRMELSEYLNKIEGHKKKLDNMRAYYYNFFRGMYEFRNGEYTRAITYYKKAERKIPTISDKIEKAEFYFKLSEVYYHMKMTHISMHYAELSYNIYKKHELYSVRRIQCHFVIAGNYDDLENHEKALPHLQEALKGAELLKSKNTHIYATAFFNLGNCYHKMDNLNKAARYIEQALVQYRKINSDVLPQAYHDLALIYFKQGKKEQAMDCFRKGIRSAVDFKDELFMNLFEALDVLYIRNGDTPKLLNIFSRLENGKGYPYLEELALLGGNLFDYNGKIEDSIICFKKMVYAQKQISKGECMYEI
What is the function of this protein?
Involved in the regulation of sporulation (PubMed:10629174).  Acts as a phosphatase that specifically dephosphorylates the sporulation initiation phosphotransferase Spo0F and inhibits its activity (PubMed:10629174).  Probably plays a dispensable role in the overall context of sporulation initiation (PubMed:10629174).
What are the official names of this protein?
Response regulator aspartate phosphatase E.
What is the protein family that this protein belongs to?
Belongs to the Rap family.
Protein: MURE_STRSV
Sequence: MIKIETVLVILKEDHNFRDIVKGEEYFFSYSGLTFDSISYDSREADASTLFFVKGEAFKKEFLEKAVSVGLRFYISETDFQVGIPVLLVNDVKQAMSLLAMEFYGHPEKKLKLLAFTGTKGKTTTAYFTYQILSQSHRPALLSTMNTTLDGETFFKSTLTTPESLDLIKMMAQALANDRTHLIMEVSSQAYLKKRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYNKRLLMDNSRAVIVNSGMDHFQIVKEQVASLEHDFYGADSSNTIKDSQAFSFEATGKLAGNYDIQLIGRFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEVLTQKNGAKVFVDYAHNGVSLRNLLSVVEEHQKGKIILLLGATGNKGESRRKDFGLLLNQHPELTVILTADDPNYEDPLAIAEEIASYISYPVEKIADREEAIKKALSLTEREGDAVILAGKGADAYQIVEGEKVAYPGDYALAEKYL
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BARQU
Sequence: MTRKSFSFFLLGLILTVGIDQTVKYWIMHNMLLGTEIPLLPFLSLYHVRNSGIAFSFFSSFSHWGLIALTLIILIFLLWLWKNTEYNKFLSRFGLTLIIGGAIGNLIDRICFYYVIDYILFYIDDIFYFAVFNLADTFITLGVIAIVTEELRIWIKEKRHSKRTFSR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_CHRVO
Sequence: MTELDQFWPACLARLEAELSSQQFNTWIKPLTAEAGDEGIALFAPNRFIMQFIKDRFLPRIEELAVELVGELPVELRLGAPTARPAAPVAGNSQPKAKEPAKAAASAPAAPSPAKQAAVKAIGGSHESTRLNPSFTFDTLVTGKGNQLARAAAMQIAENPGDQAYNPLFVYGGVGLGKTHLIQAIGNHVFQKNPQAKIRYIHAERYVADIMRAYQHKAFDEFKRYYHSLDLLLIDDIQFFAGKNRTQEEFFYAFNALIEGGKQVIMTCDSYPKQIEGMEERLISRFSWGLTVEIQPPELEMRVAILMKKAEADSIKLEHNVAFFIAQNVRSNVRELEGALKRVVAYARFTSQNITLELVKEALKDILAAGNRQVTVDAIQKTVAEYYKIKLSDMHSKKRSRDIARPRQVAMALAKELTQLSLPNIGDAFGGRDHTTVLHACKTITEMRASDADIAHDYEALLSMLRN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_BRASB
Sequence: MADNTVTDVKKLSFERAIEELESIVKRLEDGKVPLEESVAIYERGEALKRRCEELLRQAEARVEKITTDASGRATGVAPLDVQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M660_ARATH
Sequence: MRPFGEAKFLSGHQTLQLMRKKALWSKGKRVRCHTPCLPKVPRGRARRSGATTREQSPHRQGDRRRPSQGTSRPTGKTGETREGNPIGSQRIHSTCSPTDFIFLILESGGKGSLFCNEKKKRSRFDSAQPNDTSNTNDLCLECVARSLF
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00660, ORF149.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y1373_LACPL
Sequence: MYLLGHIIGWLWLMLTVAIGLSRHSVKSANRFLILSRIGYLLIIITGVALAIRTLSGNWWLTLLKVILGLGTIGLIEVAFARKQESHLNSGLVTLLVCGTLLTIICGIGLHWQLTGNLI
What are the official names of this protein?
UPF0344 protein lp_1373.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S19A1_CRIGR
Sequence: MVPTGQVAEKQACEEPRQDRELKSWRCLVFYLCFFGFMAQLRPGESFITPYLLQQNFTIEQVTNEIIPVLPYSHLAVLVPIFLLTDYLRYKPILILQCLSFMCVWLLLLLGTSVVHMQLMEVFYSVTMAARIAYSSYIFSLVRPSRYQRMASYSRAAVLLGVFTSSVLGQVLWPLEQKSQNSNMLNYISLGFIIFSLGLSLFLKRPKHSLFFNRSALVHKALPCELDQMHPGPGRPEPGKLERVLGSCRNSFLVCMLSELVGNLRQPQLRLWCLWWVFNSAGYYLIVYYVHVLWSIDKNLNYNGAVDAASTLLSAITSFSAGFVKIRWALWSKLVIASVIAIQAGLVFCMYMVHYVTWVHKIWVLYMTYVLFRGAYQFLVPIATFQIASSLSKELCALVFGINTFLATALKTAITLVVSDKRGLGLKVEKQFCIYSVYFMVLSVICFVGAVLDGVRYCRRGRHQPLPLPQELSPLENSVQVPSMQDGGLGGLQPSAPQLLPEDGVEDSEASLRAEAKA
What is the function of this protein?
Antiporter that mediates the import of reduced folates (By similarity).  Mechanistically, acts as a secondary active transporter, which exports intracellular organic anions down their concentration gradients to facilitate the uptake of its substrates (By similarity).  Has high affinity for N5-methyltetrahydrofolate, the predominant circulating form of folate.  Also able to mediate the import of antifolate drug methotrexate (By similarity).  5-amino-4-imidazolecarboxamide riboside (AICAR), when phosphorylated to AICAR monophosphate, can serve as an organic anion for antiporter activity (By similarity).
What are the official names of this protein?
Reduced folate transporter, Methotrexate uptake protein, Plasma membrane folate antiporter SLC19A1, Reduced folate carrier 1, RFC-1, RFC1, Solute carrier family 19 member 1.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: KPRS_BORBR
Sequence: MIFTGTANTRLAVDVVNHLDMSLGKMTVGRFSDGEVMVEINENVRGKDVFVLQPTCAPTNDNLMEIMVMVDALRRASAGRITAAIPYFGYARQDRRPRSARVAISAKVVANMLQVAGVDRVLTMDLHADQIQGFFDIPVDNIYAGPILLGDIWRRNFSNLVVVSPDIGGVVRARALAKQLEADLAIIDKRRPRANVSEVMNIIGEVDGRTCIIMDDMVDTAGTLCKAAQALKDRGAGAVYAYCTHPVLSGGAIERIETSSLDELVVTDTIPLSEQGQACGKIRQLSCAALLGETILRISNAESVSSLFAD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AJL2_ANGJA
Sequence: MVSFKLPAFLCVAVLSSMALVSHGAVLGLCEGACPEGWVEHKNRCYLHVAEKKTWLDAELNCLHHGGNLASEHSEDEHQFLKDLHKGSDDPFWIGLSAVHEGRSWLWSDGTSASAEGDFSMWNPGEPNDAGGKEDCVHDNYGGQKHWNDIKCDLLFPSICVLRMVE
What is the function of this protein?
Involved in host defense at the body surface.  Causes agglutination and suppresses the growth of the Gram-negative bacterium E. coli K12.  Possesses calcium-independent hemagglutinating activity.
What are the official names of this protein?
Lactose-binding lectin l-2, Ajl-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_XYLFA
Sequence: MESQLFNAPAKKAFGQHFLVDRYYIDRIIHAITPQPNDHIVEIGPGQGAITLPLLKCCGSLTAIELDRDLIAPLTAAATPLGKLDIIHRDVLTVDLSILAKPGNKKLRLVGNLPYNISSPILFHVLQQAAIIADMHFMLQKEVVDRMAAPPGSKVYGRLSVMLQAWCEVTTMFVVPPDAFQPPPKVNSAITRLVPRDPTTIRIADTKRFSDIVRAAFGQRRKTLRNSLADICTPAHFEHAGIRTNARAEQLEVTEFIALANAKDT
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUCL_MACFA
Sequence: MVKLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVATPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEEDDSEEDDEDDEDEDEDEDEIEPAVMKAAAAAPASEDEDDEDDEDDEDEDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDEDDDDEDEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
What is the function of this protein?
Nucleolin is the major nucleolar protein of growing eukaryotic cells.  It is found associated with intranucleolar chromatin and pre-ribosomal particles.  It induces chromatin decondensation by binding to histone H1.  It is thought to play a role in pre-rRNA transcription and ribosome assembly.  May play a role in the process of transcriptional elongation.  Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats (By similarity).
What are the official names of this protein?
Nucleolin.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: CMOA_YERPP
Sequence: MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPANRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQAGFEHAEVWFQCFNFGSLIALKAGEAQ
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: GPMI_STAS1
Sequence: MAKQPTALIILDGFANRESEHGNAVKLANKPNFDRYYSKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRVVYQSLTRINKSIEDGDFFENDVLNNAINHVKKNDSVLHVFGLLSDGGVHSHYKHLFALLDLAKKQGLEKVYVHAFLDGRDVDQKSALKYIEETEAKFKELGIGQFASVSGRYYAMDRDKRWDREEKAYNAIRNFGGTTFESAKAGVEANYDKDLTDEFVEPFIVQDQNEGVNDGDAVIFYNFRPDRAGQLSEIFTDKAFEGFKVEQINDLFYATFTKYNDNVNAEIVFEKVDLTNTIGEVAQDNGLKQLRIAETEKFPHVTYFMSGGRNEEFEGERRRLIDSPKVATYDLKPEMSAYEVKDALIEELNKGDLDLILLNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKITEMGGHAIITADHGNSDMVLTDDDQPMTTHTTNPVPVIVTKDGVTLRETGRLGDLAPTLLDLLNVDQPEDMTGESLINH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: KPYK_BUCAI
Sequence: MLNRLRRTKIVATLGPSTDINNNLEKIIRSGVNVLRFNFSHGSKDEHKSRANQAREIMTRLNFHIALLGDLQGPKIRISKFIKNNIFLNVGDFFILDANLDQNNGNQERVGIDYKQLPYDLKVGDVLLLDDGRIQLKVIKSTGHEILTKVVIGGILSNNKGINKLGGGLSADALTEKDKKDIILATEINVDYLAISFPRCSNDLKQARKLAKEFGSNAKIIAKIERAEAVLNQNTIEDIILASDAIMIARGDLGVEIGDSELAGIQKKLIRTARQLNRIVITATQMMESMITNPLPTRAEVMDVANAVLDGSDAVMLSAETASGEYPAETVIKMAKICKGAEKVPSINVSRHRIHAKFDDIEEAIAMSAMYVANHLKGITAIITMTESGKTALMTSRITSGLPIFALSKNKETLNLASLYRGVTPIYFNSKNNNFKAANEAIVLLRKRGFLCRGELVIITQGDIMGKIGKTNTSRILKVV
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: PC20_PENCR
Sequence: MRDSLGPFRTFTLLTVGLLLSLCVIKTVKHRRRYHRLPTPPHSMLLGNLGVVLAEILASPEGFFHLFCVENIRRKYNMPSVFYLDLWPILPSIMVVAEPAVAKHMTQVQPLQRERFSPNLFSPLLTAEFILAMEQKNWKKENPALNAALTSTRVNEATSLLAPSLHSLRSRLHSISQSGKQYPIKDLLISYIIEVGGVIQLGGSFDLLAETSALDPIIKRSLDMMGWNPVKRYIYSKEIKQRTDCLNKVLVETIQNTAQTGESGKMSQSPIYLAHYCYLFLHKHPDCLREMREEHDRVFSPDRTQTWELLQKEPHRINSLHFTLAVVKETLRLIGVGGAFICHLAMGRRADLFPDPDAFRPHRFLPGANPSIPADSFRPFEKGHLSCPGQNLALKSLVLLLLTTSREFDLVPVFPKGAPQAAEYLGGKGYPEFHIGPHVNKGMPVMVHTRVDA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase penG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase penC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation by the FAD-dependent monooxygenase penM leads to a epoxidized-GGI that is substrate of the terpene cyclase penB for cyclization to yield paspaline (Probable).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase penP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase penQ (PubMed:26213965).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase PC-15 which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase penD (Probable).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase PC-16 and the P. simplicissimum ptmI-ortholog not yet identified in P. crustosum, leads to the production of the prenylated form of penijanthine (Probable).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase PC-22 (Probable).  A series of oxidation steps involving 4 cytochrome P450 monooxygenases (PC-21, PC-05, PC-23, PC-20) and a FAD-dependent monooxygenase (PC-14) are required for the transformation of PC-M4 to penitrems A and E.  Synthesis of these final products is proposed to proceed via penitrems D and C (PC-21, PC-05, PC-14) and penitrems B and F (PC-21, PC-05, PC-14, PC-23) (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase PC-20, Penitrem biosynthesis cluster protein PC-20.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLSB_MYCTO
Sequence: MTKPAADASAVLTAEDTLVLASTATPVEMELIMGWLGQQRARHPDSKFDILKLPPRNAPPAALTALVEQLEPGFASSPQSGEDRSIVPVRVIWLPPADRSRAGKVAALLPGRDPYHPSQRQQRRILRTDPRRARVVAGESAKVSELRQQWRDTTVAEHKRDFAQFVSRRALLALARAEYQILGPQYKSPRLVKPEMLASARFRAGLDRIPGATVEDAGKMLDELSTGWSQVSVDLVSVLGRLASRGFDPEFDYDEYQVAAMRAALEAHPAVLLFSHRSYIDGVVVPVAMQDNRLPPVHMFGGINLSFGLMGPLMRRSGMIFIRRNIGNDPLYKYVLKEYVGYVVEKRFNLSWSIEGTRSRTGKMLPPKLGLMSYVADAYLDGRSDDILLQGVSICFDQLHEITEYAAYARGAEKTPEGLRWLYNFIKAQGERNFGKIYVRFPEAVSMRQYLGAPHGELTQDPAAKRLALQKMSFEVAWRILQATPVTATGLVSALLLTTRGTALTLDQLHHTLQDSLDYLERKQSPVSTSALRLRSREGVRAAADALSNGHPVTRVDSGREPVWYIAPDDEHAAAFYRNSVIHAFLETSIVELALAHAKHAEGDRVAAFWAQAMRLRDLLKFDFYFADSTAFRANIAQEMAWHQDWEDHLGVGGNEIDAMLYAKRPLMSDAMLRVFFEAYEIVADVLRDAPPDIGPEELTELALGLGRQFVAQGRVRSSEPVSTLLFATARQVAVDQELIAPAADLAERRVAFRRELRNILRDFDYVEQIARNQFVAREFKARQGRDRI
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSG1_ORYSA
Sequence: MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDASSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVISPRYDQYKDAWDTSVVAEIKVADRYERVRFFHCYKRGVDRVFIDHPSFLEKVWGKTGEKIYGPDTGVDYKDNQMRFSLLCQEAPRILNLNNNPYFKGTYGEDVVFVCNDWHTGPLPSYLKNNYQPNGIYRNAKVAFCIHNISYQGRFAFEDYPELNLSERFKSSFDFIDGYDTPVEGRKINWMKAGILESDRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSKDKYITTKYDATTAIEAKALNKEALQAEAGLPVDRKVPLIAFIGRLEEQKGPDVMAAAIPELMQENVQIVLLGTGKKKFEKLLKSMEEKYPGKVRAVVKFNAPLAHLIMAGADVLAVPSRFEPCGLIQLQGMRYGTPCACASTGGLVDTVIEGKTGFHMGRLSVDCKVVEPSDVQKVATTLKRAIKIVGTPAYNEMVRNCMNQDLSWKGPAKNWENVLLGLGVAGSEPGVEGEEIAPLAKENVAAP
What is the function of this protein?
Required for the synthesis of amylose in endosperm.
What are the official names of this protein?
Granule-bound starch synthase 1, chloroplastic/amyloplastic, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule-bound.
Protein: RL24_CAUSK
Sequence: MAAKIKKGDRVVVLAGKDKGKQGAVTQVLVKANRVLVQGVNLVQRHTKATQADPQGGIKSKEAALHVSNVAIVDSKGKPTRVGFKIEGDKKVRFAKTTGEVING
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MMSA_HUMAN
Sequence: MAALLAAAAVRARILQVSSKVKSSPTWYSASSFSSSVPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR
What is the function of this protein?
Plays a role in valine and pyrimidine metabolism.  Binds fatty acyl-CoA.
What are the official names of this protein?
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member A1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MT2Z_SOLLC
Sequence: MSGCGGSCNCGSSCSCGKGGGCNMYPDLEKSTTLTIIEGVAPMNNKGMVEGSIEKATEGGNGCKCGSSCKCDPCNCCSASTIWT
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein type 2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: RPOY_LACP3
Sequence: MIYKVLYQKDKIQNPRRETTQTLYLEAPSAVEARALVEKNTPYNIEFIQELSGNFLEYEEKSANFKLTTF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.