PharMolix/UniProtQA huggingface dataset:
Protein: Y1112_NEIMF
Sequence: MTEQKNKTSLIEFPCTFPLKVMGAVHPEFEQAVLDTVRLHAPDTQAHHITTRPSSKGNYTGATVQVKVENQEQLDNIYRALTSHKLVKVVL
What are the official names of this protein?
UPF0250 protein NMC1112.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: PYRDB_CARHZ
Sequence: MNLKVKIGELTLKNPVMPASGTFGFGLEFKDIFDLKNLGALVVKTITKNPRLGNRPPRVYEVSCGMINSIGLANPGWDYFCEKILPQIKDLNDILILNIAGESVEEFQYLAREAQRFDEIKALELNVSCPNVSKGGIAFGTDLEALKQIVSSVRKIYSKTLIVKLTPNVTDITVYAKAAENAGADALTLINTFTGMVIDVKSKKPILGNKHGGVSGPAIRPMAVKMVYDCFKAVSIPIIGVGGIDSKEAALEFFLAGATAIQVGSQNFVEPGFMPRLIRELGEYLQEENIESIAKLTGLAHRGEENV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_STAAE
Sequence: MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFVDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DC1L2_RAT
Sequence: MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVFGEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLKFAVSAESLRETLVIFVADMSRPWTIMESLQKWASVLREHIDKMKIPPEEMRDLERKFMKDFQDYIEPEEGCQGSPQRRGPLTSGSDEDNVALPLGDNVLTHNLGIPVLVVCTKCDAVSILEKEHDYRDEHLDFIQAHLRGFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTIPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQESPARGPSGSPRTQGRGGPASVPSASPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPSAGGVQSTAKKSGTEGEPQSFRSLTEQCCQTGQKTVLSNVQEELDRMTRKPDSMVTNSSTENEA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in binding dynein to membranous organelles or chromosomes.
What are the official names of this protein?
Cytoplasmic dynein 1 light intermediate chain 2, Dynein light intermediate chain 2, cytosolic, LIC-2, LIC53/55.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS12_HAEI8
Sequence: MATINQLVRKPRVKKVVKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRIRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVKDRKQGRSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PRXD1_HUMAN
Sequence: MAGAELGAALEQRLGALAIHTEVVEHPEVFTVEEMMPHIQHLKGAHSKNLFLKDKKKKNYWLVTVLHDRQINLNELAKQLGVGSGNLRFADETAMLEKLKVGQGCATPLALFCDGGDVKFVLDSAFLEGGHEKVYFHPMTNAATMGLSPEDFLTFVKMTGHDPIILNFD
What are the official names of this protein?
Putative prolyl-tRNA synthetase associated domain-containing protein 1, PrdX deacylase domain-containing protein 1, Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene.
What is the protein family that this protein belongs to?
Belongs to the PRORSD1 family.
Protein: PSEC_CAMJE
Sequence: MLTYSHQNIDQSDIDTLTKALKDEILTGGKKVNEFEEALCEYMGVKHACVLNSATSALHLAYTALGVQEKIVLTTPLTFAATANAALMAGAKVEFIDIKNDGNIDEKKLEARLLKESENIGAISVVDFAGNSVEMDEISNLTKKYNIPLIDDASHALGALYKSEKVGKKADLSIFSFHPVKPITTFEGGAVVSDNEELIDKIKLLRSHGIVKKRLWDSDMVELGYNYRLSDVACALGINQLKKLDHNLEKREEIANFYDKEFEKNPYFSTIKIKDYKKSSRHLYPILLFPEFYCQKEELFESLLHAGIGVQVHYKPTYEFSFYKKLLGEIKLQNADNFYKAELSIPCHQEMNLKDAKFVKDTLFSILEKVKKGYCG
What is the function of this protein?
Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.
What are the official names of this protein?
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase, Pseudaminic acid biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
Protein: TSAD_PARMW
Sequence: MTSVLALETSCDESAAALVWRDADGRFEVSSARIASQVEEHARWGGVVPEIASRRHVEALPGLIQQVLDESDSTLAEVDAIAATVTPGLAGALMVASVTGRTLSALRDRPFLAVHHLEGHLASVHLAEHRPQLPYLVLLVSGGHTELIRVEADGAMERLGRSHDDAAGEAFDKVARLLGLGYPGGPAIQAAAEGGDGRRFKLPKGRISLPEGGFHPYDFSFSGLKTAMLRTVEAQSGPLPTADLAASFEQVVVDVLVERSLRCAMDHGLEELVMVGGVAANRRLRQTLEQRSNAVGVRVSVAPLAYCTDNAAMIGAAALLRWDAGARGCSLRTGVSARWPLAQVDQLYTEQPAF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_PROM9
Sequence: MNDRIIEFDPLIEGVLINRYKRFLADIELETGEVVTAHCANTGPMKGLLTEGAKVRMSVSPSPKRKLPFTWEQICVLDAKNEEVWVGINTLFANKLIKKVIEKNLLNEIIGEIETIKAEVPYGKDKKSRIDFFLTPKSSNPDKRNIYIEVKNTTWMKGNVALFPDTVTKRGQKHLIELKELIPASKSILILCITRKDACFFSPGDDADPLYGNLFRESFSAGMIPIPCSFEFHKDHITWNGIKPLK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: SYV_YERPS
Sequence: MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTGSLHMGHAFQQTIMDTLIRYQRMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLHKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPETVLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVAEFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVRTAPLAKVAIEAVENGEIQFVPKQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVALRQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHFMKDENGKPQVPFKTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMMQPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYEFTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVKNLKGITADTIMLQPFPEYDASQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVMLRGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSVTKLVEGAEVLIPMAGLIDKATELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQATIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_THEMA
Sequence: MRHRVKRHKLGRYGSHRKSLLRNLSREIVEHGSIVTTTAKAKALKTFMDKLVSKAIEAATTDDRARSVHLRRQINAVLGDRRLTNKLVDEIAKNYVGRRGGYVRVLRIGFRRGDAAEMSLVQLVEASSQEG
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ATP6_MARMS
Sequence: MGIESPTASSYIKHHLQNLTYGQHPDGTWGLAHDAKEAADMGFWAIHVDTMAISIALGFLFLWLFRKAAKKISADTPSGLQNFVELMVEFVDGSVKETFHGKSKVIAPLALTIFVWVFLMNFMDLIPVDFLPATAQWIGVTLFGADPHHVYFKFVPTTDINATLGMSLSVFVLIVFYSIKVKGISGFVGELTLQPFGKWMIPFNLLLEGVGLLAKPVSLALRLFGNLYAGELIFILIAILPWGVQWALSVPWAIFHILIIVLQAFIFMMLTIVYLSMAHENH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CACB1_RAT
Sequence: MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSRTPPNPLLNRTMATAALAVSPAPVSNLQGPYLVSGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLWALSRQDTFDADTPGSRNSVYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEEEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYIR
What is the function of this protein?
Regulatory subunit of L-type calcium channels.  Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity).  Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane (Probable).  Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit.  Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (By similarity).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel beta subunit family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.
Protein: LRGB_BACAN
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EGLN1_RAT
Sequence: PRAQPAPAQPRVAPPPGGAPGAARAGGAARRGDSSTAASRVPGPEDATQAGSGPGPAEPSSEDPPPSRSPGPERASLCPAGGGPGEALSPSGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELKPNSVSKDV
What is the function of this protein?
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins.  Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A.  Also hydroxylates HIF2A.  Has a preference for the CODD site for both HIF1A and HIF1B.  Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.  Under hypoxic conditions, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, heterodimerization with HIF1B, and increased expression of hypoxy-inducible genes.  EGLN1 is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality.  Target proteins are preferentially recognized via a LXXLAP motif.
What are the official names of this protein?
Egl nine homolog 1, Hypoxia-inducible factor prolyl hydroxylase 2, HIF-PH2, HIF-prolyl hydroxylase 2, HPH-2, Prolyl hydroxylase domain-containing protein 2, PHD2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic. Shuttles between the nucleus and cytoplasm. Nuclear export requires functional XPO1.
Protein: SYR_BRUA2
Sequence: MNIFADFDARIKKTFQDIDLKPKDGGELDLSRIGVEPPRDASHGDIATNAAMVLSKAVGQNPRELAARIAEALKADEDVESVDVAGPGFINLRLKASYWQRELLVMLNEGTDFGRSRLGAGKKVNVEYVSANPTGPMHVGHCRGAVVGDVLANLLKFAGYDVVKEYYINDAGAQIDVLARSVMLRYREALGESIGEIPAGLYPGDYLVRVGQELAGEFGTKLLEMPEAEALAIVKDRTIDAMMAMIRADLDALNVHHDVFYSERKLHVDHARAIRNAINDLTLKGHVYKGKLPPPKGRLPEDWEDREQTLFRSTEVGDDIDRPLMKSDGSFTYFAGDVTYFKDKYDRGFNEMIYVLGADHGGYVKRLEAVARAVSDGKAKLTVLLCQLVKLFRNGEPVRMSKRAGEFITLRDVVDEVGRDPVRFMMLYRKNDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQAADQLGLVDLDRVAMGSHFEKLTDESEIALVRKLAEYPRLIESAAIHQEPHRLAFYLYDLASSFHSQWNRGAENPDLRFIKVNDPDLSLARLGLVQVVSDVLTSGLTIIGADAPTEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_RICCN
Sequence: MINVEIVRNYNKWREHKQINKSLIKKITQNILLRFDNFSKIKQFELSILLTNAAEILTLNKQFRNIEKATNVLSFPSNELNWQDLYSKLEFLGDSDYMHLGDIAFCYEVIYNESCEQHKTFENHFIHLLIHSILHLIGFDHQNDTEANIMENLEIEILSYFGIFPPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_BRUAB
Sequence: MSASVSPLAPKHYPAMPVIHGVRIATAAAGIKYKGRTDLMLMVFDRPAEAAGVFTRSLCPSAPVDFCRRNLVHGKARAVVVNSGNANAFTGLKGREATQATAEAAAKAIGCATTDIFLASTGVIGEPLDAGKFSHLLGDMAESATEDFWTEAAKAIMTTDTYPKVATETVLLGQVPVTINGIAKGAGMIAPDMATMLSFVVTDAPIKADALQSLLSKGVGSTFNSVTVDSDTSTSDTLMLFATGTAAERGAPEITDAADKRLADFKKALGRVLKSLALQVVRDGEGARKMVEVEVTGAKSAASAKKIALSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLAIWFGDIRVAHQGERDPAYSEDATSAYMEGEDIRIRVDLGIGRGKATVWTCDLTKEYVAINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIC_ECO81
Sequence: MDIIGGQHLRQMWDDLADVYGHKTALICESSSGVVNRYSYLELNQEINRTANLFYVLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESTWILQNSQACLLVTSAQFYPMYQQIQQEDASELRHICLTDMALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDQQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEICDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFCFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: LSM7_SCHPO
Sequence: MSSLQKRPGPGNSSQPTERPRKESILDLSRYQDQRIQATFTGGRQITGILKGFDQLMNLVLDDVEEQLRNPEDGKLTGAIRKLGLVVVRGTTLVLIAPMDGSEEIPNPFVQAE
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.  Probable component of the spliceosome.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm7.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMU_CLOAB
Sequence: MYKCALILAAGKGKRMKSDLPKVLHKVCDKEMVNHVIDTMRKSELQDVNVVIGKGAELVREATSKKNISYSLQSEQLGTGHAVKCAEDFLRGKDGVVAIFTGDAPLITEDTVKNLIDFHEKGGYKATIITALIDNPEGYGRIIRNVDGSVKKIVEHKDCTEDELKVKEINSAMYCFDIKSLLESLDKLNNNNVQGEYYLTDVIGILEEEGAKIGAISVPFEEILGVNSRLQLCQVGKVMQKRINEKHMENGSTLIDPDNTYIGADVEIESDTIIYPGNVLQGKTVIKTGCVLYPNSRIEDSVIGKNVTVQSSVILESKVGEDTTVGPFAYIRPESNIGNKVRIGDFVEIKKSTIGNNTKVSHLTYIGDAEVGEGCNFGCGTVVVNYDGKDKHKTVIGNKSFIGCNTNLVSPVTVEDNTYIAAGSTITNKVPEGSLAIARAKQVVKEGWVDKKGLLK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI2_SYNFM
Sequence: MSSAWEAVRALASGFATTFVHLFRKPVTEEYPEVKRALPARTRAVIVLTRDPDGGERCVACYLCSAVCPVSCISMQAAEREDGRRHAAWFRINFARCIYCGLCEEACPTSAIQLTPFFETCERDILKLVYEKEDLLVDHQGKDKEYNFYKYAGVTTDVGGKGEHVQEDEPVDLRSNLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRUB_BACCN
Sequence: MEGVVLLHKPKGMTSHDCVFKLRKILREKRIGHTGTLDPDVTGVLPICVGRATKIAQFLTSETKTYEGEVTLGFSTTTEDASGEVVEKQDVNRTITRKEIEAVLAELTGTLEQVPPMYSAVKVNGKKLYEYARAGQEVKRPVRIITIHEFTLLDNRETFEGANISFRFRVTCSKGTYVRTLAVMIGEKLGFPAHMSDLVRTASGEFQLHDCVSFEEIEENMQNGTVESVFISIDEALSKFPKIVVDEKQAEKIKNGMFLKNEIQAETPFITVFDRNNHCLAIYEHHPKRPGMLKPMKVLVNNQELKL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: EFG_ERWT9
Sequence: MARTTPITRYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMAQEQERGITITSAATTAFWSGMAKQFEPHRVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVSQIKSRLAANPVPIQLAIGAEEKFTGVVDLVKMKAINWNEADAGVTFEYEEIPADMQELAEEWHQNLVESAAEASEELMEKYLGGEELTEEEIKKALRQRVLNNEVILVTCGSAFKNKGVQAMLDAVIEYLPAPTDVTAINGILDDGKDTPAVRHSDDKEPFAALAFKIATDPFVGNLTFFRVYSGVVNSGDTVMNPVKSQRERLGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPSNVIILERMEFPEPVISVAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESGQTIIAGMGELHLDILVDRMKREFNVEANVGKPQVAYRETIRETVKDVEGKHAKQSGGRGQFGHVVIDMGPLEAGGPGYEFVNDIVGGSIPKEFIPAVDKGIQEQLKSGPLAGYPVVDIKVRLHYGSYHDVDSSELAFKLAASLAFKSAFGKAKPVLLEPVMKVEVETPEDYMGDVIGDLNRRRGMIEGMEDTSTGKTVRAQVPLSEMFGYATDLRSQTQGRASYSMEFLKYAEAPNNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SICP_SALTS
Sequence: MGLPLTFDDNNQCLLLLDSDIFTSIEAKDDIWLLNGMIIPLSPVCGDSIWRQIMVINGELAANNEGTLAYIDAAETLLLIHAITDLTNTYHIISQLESFVNQQEALKNILQEYAKV
What is the function of this protein?
Molecular chaperone required for SptP stabilization and secretion.
What are the official names of this protein?
Chaperone protein SicP.
What is the protein family that this protein belongs to?
Belongs to the SicP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ECO27
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.