PharMolix/UniProtQA huggingface dataset:
Protein: PDR1_NICPL
Sequence: MEPADLSNLRGRSLRASIRGSMRGSIRENSNSIWRNNGAEVFSRSARDEDDEEALKWAALEKLPTYDRLRKGILFGSQGAAAEVDVDDSGVLERKNLLERLVKVADEDNEKFLLKLKNRIDRVGIDFPSIEVRFEHLNIDADAYVGSRALPTFTNFISNFVEGLLDSIHILPSKKRQVTILKDVSGIVKPCRMTLLLGPPGSGKTTLLLALAGKLDSALKVTGKVTYNGHELHEFVPQRTAAYISQHDLHIGEMTVRETLEFSARCQGVGSRYEMLAELSRREKAANIKPDADIDMFMKAASTEGQEAKVVTDYILKILGLDICADTMVGDQMIRGISGGQKKRVTTGEMIVGPSKALFMDEISTGLDSSTTYSIVNSLKQSVRIMKGTALISLLQPAPETYNLFDDIILLSDGYIVYEGPREEVLEFFESMGFKCPERKGAADFLQEVTSKKDQQQYWIRRDEPYRFITSKEFAEAYQSFHVGRKVSDELKTTFDKSKSHPAALTTQKYGIGKRQLLKVCTERELLLMQRNSFVYLFKFFQLLIIALMTMTIFFRTKMPRDSAEDGGIYSGALFFVVIMIMFNGLSELPMTLYKLPVFYKQRDFLFYPSWAYAIPSWILKIPVTFAEVGMWVFLTYYVMGFDPNVGRFFKQFLLLLLVNQMASALFRFIAAVGRTMGVASTFGAFALLLQFALGGFILARNDVKDWWIWGYWTSPLMYSVNAILVNEFDGQKWKHIVAGGTEPLGAAVVRARGFFPDAYWYWIGVGALAGFIVMFNIAYSVALAYLNPFDKPQATISDESENNESESSPQITSTQEGDSASENKKKGMVLPFDPHSITFDEVVYSVDMPPEMRESGTSDNRLVLLKSVSGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIDGSIKISGYPKKQDTFARISGYCEQNDIHSPYVTVFESLVYSAWLRLPQDVNEEKRMMFVEEVMDLVELTPLRSALVGLPGVNGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELFLMKRGGQEIYVGPLGRQSCHLIKYFESIPGVSKIVEGYNPATWMLEVTASSQEMALGVDFTDLYKKSDLYRRNKALIDELSVPRPGTSDLHFDSEFSQPFWTQCMACLWKQHWSYWRNPAYTAVRLIFTTFIALIFGTMFWDIGTKVSRNQDLVNAMGSMYAAVLFLGVQNSSSVQPVVSVERTVFYREKAAGMYSAIPYAFAQVLIEIPYIFVQATVYGLIVYSMIGFEWTVAKFFWDFFFMFFTFLYFTFFGMMTVAVTPNQNVASIVAGFFYTVWNLFSGFIVPRPRIPIWWRWYYWGCPIAWTLYGLVASQFGDLQDPLTDQNQTVEQFLRSNFGFKHDFLGVVAAVIVAFAVVFAFTFALGIKAFNFQRR
What is the function of this protein?
Excretes secondary metabolites such as terpenes.  Involved in both constitutive and jasmonic acid-dependent induced defense.  Confers some resistance to sclareol and B. cinerea.
What are the official names of this protein?
Pleiotropic drug resistance protein 1, NpPDR1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYOC_CANLF
Sequence: MPTAQLLLLACLLWGLEARTAQLRKANDRSGRCQYIFSVASPNESSCPEQGQAMSAIQDLQRDLESTKARLSSLEGLLHQLTLGQAAGPSESQEGLHRELGTLRKEREQLETQARELEVAYSNLLRDKSALEEEKRRLGEENEDLAQRLEHSSQEVARLRRGQCPQAHSSSQDVPAGSREVSKWNVETVNFQELKSELTEVPASRILKESPSGHPRNEEGDSGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPHTRETTWRIDTVGTDIRQVFEYELASQFLQGYPSKVHVLPRPLESTGAVVYRGSLYFQGAGSGTVVRYELTAETVKAEREIPGAGYHGQFPYSWGGYTDIDLAVDETGLWVIYSTQEAKGAIVLSKLNPETLELEQTWETNIRKQSVANAFVICGHLYTISSYSSPDATVNFAYDTGTGRSRVLSIPFKNRYKYSSMIDYNPLEKKLFAWDNFNMVTYDIRLSKM
What is the function of this protein?
Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration.  Promotes substrate adhesion, spreading and formation of focal contacts.  Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction.  Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways.  Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling.  Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling.  Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling.  Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex.  Involved in positive regulation of mitochondrial depolarization.  Plays a role in neurite outgrowth.  May participate in the obstruction of fluid outflow in the trabecular meshwork.
What are the official names of this protein?
Myocilin.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Cytoplasmic vesicle. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Secreted, extracellular exosome. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion inner membrane. Mitochondrion outer membrane. Rough endoplasmic reticulum. Cell projection. Cell projection, cilium. Note=Located preferentially in the ciliary rootlet and basal body of the connecting cilium of photoreceptor cells, and in the rough endoplasmic reticulum. It is only imported to mitochondria in the trabecular meshwork. Localizes to the Golgi apparatus in Schlemm's canal endothelial cells. Appears in the extracellular space of trabecular meshwork cells by an unconventional mechanism, likely associated with exosome-like vesicles. Localizes in trabecular meshwork extracellular matrix. SUBCELLULAR LOCATION: [Myocilin, C-terminal fragment]: Secreted. SUBCELLULAR LOCATION: [Myocilin, N-terminal fragment]: Endoplasmic reticulum. Note=Remains retained in the endoplasmic reticulum.
Protein: OCX32_CHICK
Sequence: MPGLRAALPAALLLLSSFPPAAAERLPWPQVPGVMRPLNPSHREAVWAAWTALHYINSHEASPSRPLALHKVVKAASKMIPRLGWKYYVHCTTEGYIHGENAGSCFATVLYLKKSPPVVHGKCVHAQNKKQIQEEDHRFYEYLQHQKKPITANYIPDSNGNIAHDHLQLWGLAIVGSSYIMWKQSTEHTGYLLAQVSSVKQQIRKDNAVAFKFIVLLHEIPTQQLNVCHMYLVWTLGHPIRVKYSCAPDNHGLEDGSGQDSGSAAGTSHETKGNF
What is the function of this protein?
Component of the matrix of the eggshell.
What are the official names of this protein?
Ovocalyxin-32, OCX-32, 32 kDa eggshell matrix protein.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I47 (latexin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_CHESB
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMTPYIFGERNNIHIIDLSQTVPLLHQALKVVSDTVGRGGRLLFVGTKRQASDIVADAARRSAQYYVNSRWLGGMLTNWKTISNSIQRLRRLDEMLSSENLGLTKKERLNLERERDKLERALGGIRDMGSTPDMMFVIDTNKEAIAVQEARRLGIPVIAVIDSNCDPDVVDYPIPGNDDAARAIALYCDLIAKAAIDGIERQQGSLGVDIGESAAAPSEPALETASAEATAEGEQPGSQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL32_PROMP
Sequence: MAVPKKKKSKSKRNHRHAVWKGKAALAAQKAMSLGKSVLTGKAQGFVYPIDEEEESEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PG082_MONPV
Sequence: MNNFVKQVASKSLKPTKKLSPLDEVISLNECIISFNLDNFYYCNDGLFTKPINTPEDVLKSLLIMESFAYEKMIIKGLIKILISRAYINDIYFTPFGWLTGVDDDPETHVVIKIIFNSSLISIKSQVIEYLKPYNVNNLSVLTTEKELSINTFNVPDSIPISIISFFPFDTDFILVILFFGVYNDSYCGISYISPKERLPYIIEILKPLVLEINMLSDEIGRTSSIRIFNSTSVKKFPTNTLTSICEIVYSFDESSFTTPKTFTPLNASPYIPKKIVSLLDLPSNVEIKAISRSGVDFITHINNKRLTTILVIAKDNFLKNSTFSGTFIKENIIWKGIYTYRIIKSSFPVPTIKSVTNKKKICKKHCFVNSQYTTRTLSHIL
What is the function of this protein?
Binds to the hairpin form of the viral telomeric sequence.  Might direct genome encapsidation into the virus particle.
What are the official names of this protein?
Telomere-binding protein OPG082.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG082 family.
Protein: CYP2_CROXC
Sequence: MTMTSLDIILFISAIVFLSIYYYNLFSNAKRSNGLKLPPGPKGYPVLGNLPQLGAKPHQALQAFSRVYGPLMRLRLGSVDLVVASSPSVAAQFLKNDSNFCARPPNSGAEHMAFNYHDLVFAPYGPRWRLLRKLSAVHLLGPKALDDNQNVREEELAVLARMLYERSRGGEPVNVGKEMHVCSTNALSRAMMGRRVFEKLAVGGGGVEEEEEMKKAEEFKDMVVEVMTLAGVFNIGDFVPWLKPFDIQGVVRKMKRVHRRYNVFLDKFIAECRSSAKPGANDLLSVLIGQRGKSDGSGGEITDTAIKALVLNLLTAGTDTSSSTIEWALTELIRHPDILKKAQQEIDSAVGRDRLVTESDVPKLPYLQAIVKENFRMHPATPLSLPRMSIEECDIGGYHIPKNSTLFVNIWAMGRDPSIWPDPMEFRPSRFLPGGQGEHLEVRGNHFELMPFGAGRRICAGTSMGIRVVHSTVATLIHAFDWKLPEGLTAEKIDMEEAFGISLQKAIPLMAHPIPRLAPKAYSPKMK
What is the function of this protein?
Flavonoid 3',5'-hydroxylase that catalyzes the 3'- and 5'-hydroxylation of flavanones, dihydroflavonols and flavonols (PubMed:31004005).  Converts narigenin to dihydrotricetin, dihydrokaempferol to dihydromyricetin and kaempferol to myricetin (PubMed:31004005).
What are the official names of this protein?
Flavonoid 3',5'-hydroxylase CYP75B138, Cytochrome P450 2, CcCYP2, Cytochrome P450 75B132.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ANKL1_CAEEL
Sequence: MPPNGAITTTPRSRMPPTTPSSGKSRPKKETLHYLAASSSTTSVDAARTLLERGANVNAIDRDGATPLHYACTHDNVAMAQLLLTFGADPMSADKLGRTAYSIAKGNTLRFLRRYKKSSNRQRLGFFRRFFACHSRNETFFIVRNNQEVAPLRPTALAEAASISFNRGNVLTNSYRCAKKKIRATFHAIRRSRSNSTATLQDVVLTSEGIRTVTTPSRRAPKATVYAKRSMSVSDLLLIPDRRDIKNEDVKTRGSPVKKTRGTGRSRTPEAILNPRKQRTPVNHHKRSKSQETKLVAMPSPNSMAYYNTSRARNAGLRPAPSAPPLSPEPAIAAVKTPKTPTTPKTSKGRSKSPANTTAYFTADESLELLGNNMEKLNIESKSAKSSKLKTPSKPTTSSSTSFSSAEDDKEAEVSTPTTVDDGEIRKIRRLREGELKSELKKFGISPAGPLDARTRRLYEKKLLIERRKITNRGYSPDADVVSCRNSPQLELVLRNGFLPADFASRARKCDENVRSEFSGNGFGYNAFCYLIMDPRILGSNVENLTLETFVRSIFYVGKGSKNRPLAHFIDARNERRDKLDKLKTCEKLKTIDELWTLGFGIPRHEISHGVSDEEAFVREASIIEAVKLKNLRNKKAGEFHGTTKSWDNITKSEYGTFLLDRALSTLKLEGIRLITEDNLPDSLYPYVNNRRGAGGGRTPKTPK
What is the function of this protein?
Endonuclease which, in association with baf-1, plays an essential role during embryogenesis in the DNA repair response following DNA damage probably by ensuring proper chromosome segregation (PubMed:22383942).  Also required during postembryonic cell divisions after DNA damage caused by ionizing radiation to ensure normal cell proliferation (PubMed:22383942).  Resolves chromatin bridges in late mitosis that result from incomplete DNA replication, defective chromosome condensation or unresolved recombination intermediates (PubMed:29463814).  Together with brc-1, contributes to genome integrity by resolving mitotic chromatin bridges that result from incomplete processing of DNA breaks (PubMed:29463814).  In parallel to the slx-1/mus-81 pathway, acts in processing early recombination intermediates in meiotic prophase I to prevent illegitimate recombination (PubMed:29879106).  Also involved in processing remaining, erroneous recombination intermediates that persist into the second meiotic division (PubMed:29879106).
What are the official names of this protein?
Ankyrin repeat and LEM domain-containing protein 1 homolog, LEM-domain containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Localizes to foci-like structures outside the nucleus (PubMed:22383942, PubMed:29463814, PubMed:29879106). In pachytene, localizes to foci both in and outside of the nucleus (PubMed:29879106). Colocalizes with air-2 between dividing nuclei in meiosis II (PubMed:29879106). In mitosis, localizes to the center of chromatin bridges that are formed in response to DNA defects (PubMed:29463814). Forms initially a ring like structure encircling chromatin bridges between two separated daughter cells until in late telophase, localizes to the center of chromatin bridges (PubMed:29463814). Colocalizes with air-2 at the midbody (PubMed:29463814). Midbody localization depends on the formation of the central spindle and the midbody and on air-2 (PubMed:29463814). Colocalizes with the central spindle component zen-4 at the central spindle (PubMed:29463814).
Protein: YUZC_BACSU
Sequence: MRYRYPWFYVYPYEVRRPPAPANNIDTFIRSAKQAAGIFADAQLVLSRIAGSRELSRRILTAAEQSDKQTIRRLIKQMGVRHEVDTVFNPDGIYISLIGTQSRMILALRWSEDRNHFASIRL
What are the official names of this protein?
Uncharacterized protein YuzC.
Protein: TIG_ECO24
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKDKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GBRL2_HUMAN
Sequence: MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
What is the function of this protein?
Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity).  Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity).  It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity).  Involved in autophagy (PubMed:20418806, PubMed:23209295).  Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (PubMed:20418806, PubMed:23209295).  Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20418806, PubMed:23209295).
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein-like 2, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, Golgi-associated ATPase enhancer of 16 kDa, GATE-16, MAP1 light chain 3-related protein.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome. Endoplasmic reticulum membrane. Golgi apparatus.
Protein: CIMA_SYNY3
Sequence: MATKKTSLWLYDTTLRDGAQREGISLSLTDKLTIARRLDQLGIPFIEGGWPGANPKDVQFFWQLQEEPLEQAEIVAFCSTRRPHKAVETDKMLQAILSAGTRWVTIFGKSWDLHVLEGLQTSLAENLAMISDTIAYLRSQGRRVIYDAEHWFDGYRANPDYALATLATAQQAGAEWLVMCDTNGGTLPGQISEITTKVRRSLGLDGQSDRQPQLGIHAHNDSGTAVANSLLAVEAGATMVQGTINGYGERCGNANLCTLIPNLQLKLDYDCIEPEKLAHLTSTSRLISEIVNLAPDDHAPFVGRSAFAHKGGIHVSAVQRNPFTYEHIAPNLVGNERRIVVSEQAGLSNVLSKAELFGIALDRQNPACRTILATLKDLEQQGYQFEAAEASFELLMRQAMGDRQPLFLVQGFQVHCDLLTPAENPAYRNALATVKVTVNGQNILEVAEGNGPVSALDQALRKALTRFYPQIADFHLTDYKVRILDGGAGTSAKTRVLVESSNGDRRWTTVGVSGNILEASYQAVVEGIEYGLRLLTCGLTNQEAISS
What is the function of this protein?
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
What are the official names of this protein?
(R)-citramalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: ZAPD_ECOHS
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDTENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: Y1688_ACIBT
Sequence: MHCDIYRSSKKDEMYIYIARPNYPDETEQADPFEKVPEAVLQAFGRATFVMHLELAPTRKLARVNVLHVLDSLQTKGFFIQMPPEGLINPNAVEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein A1S_1688.
Protein: PYRC_SHEB9
Sequence: MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALTYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRRAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPELKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNADTITLVKKPWNVPATYPLGDTNVVPIRAGEAIDWQVE
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RNP4_THEAC
Sequence: MLITKKDVEYTARKRIEKLYDFAIRTGDRRYIIEMEHIAQRMDITLPANIKRGYCKKCKTPYRNQVVRIKKNLVTVKCPVCDDIRRFQISR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNN1_SCHPO
Sequence: MKILAMDERREELSAKSTVQNVKISEAPILDGKVNNEDSHMEIDQPEGSMEEDDHRQVKEKNTSENSVEQKRGRRMFGALLGTLGKFQQESEREQKSARKVKRAELEEKLAKRREQELQELEKQEKIEAEILESRLQEQRKVALDELELDRNDLKKVLDNKKSYYLRTKTQPSLFYRPYYLLPSQRTQLEQMKSEAP
What is the function of this protein?
Transcriptional activator that may participate in the regulation of mRNA splicing.
What are the official names of this protein?
Pinin homolog 1.
What is the protein family that this protein belongs to?
Belongs to the pinin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HIS8_XANCP
Sequence: MSTASVMDLVRDDLRAFAGYASARTSALQGDVWLNANESAWGNPADPDASTRRYPDPQPKGLRAALAQLYGCATEQLLIGRGSDEAIDLLVRGLCVPERDAVVVTPPVFGMYAVCARLQSAPLVEVPLVDGADGLHADVPAIVQAALDAKAKLVFLCSPSNPAGSAIPLAEIEAALQALQGKAVVVVDEAYGEFSDVPSAIGLLARYDNLAVLRTLSKAHALAAARIGSLIANAELIALLRRCQAPYPVPTPCAVMAEQALSAPALAVTQRRVTEIRAERARLHAALVQVAGVRQVYPSQGNFLLVRFDDAEAAFQALLEAGVVVRDQRAVPRLSDALRITIGTPDQNDRVLGALQRKQEAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: C2D1_DROME
Sequence: MFSRKKPEPAKRRQHDLSQFGLTEIPDDFDPSAGYGEDDGGDSDLEAELAAITGGEGAKPKPKPKAKLLPASDLDKMIADSLRDVSDDDDDDNLESDPDLLGELSGIGGLEEAEEEEPVAQPPAASEEPVQTFLPTTTVDTLSIIKQRLEMYKQAEANAKTAGDSGKARRFGRGLKTLKDLHRQAAAGKSINVDDIPPEVSVKPIGGQAPPVPAEESPAPSTPASPPPVPSRAAPDPPTPGTPVEPTTSVAPTSPPNPLVTQMRSRQTDYKAAALQSKRSGDISTALQFLKVVKQFDVVIKMCEDGQEVDLSDMPPPPAEFLEFLKKMQEEAAAEAVAEPTAAPEPTPVAPAPVLAAATNMLEALQQRLEKYQSVEAAAKAENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELPVPPGFGPLPTADAAPVAPTPSLPTSPTSPPPTASTSAGGTPSSSSATTPTAPRKAPSPPKPKELTTRTSGNQQKNNIAEQQMKLLLERQKEFKLAAIEAKKAGEIDQAKEYLKIFKGFDSLLNAASSGLPVDLSTLPVPPSQRDNLEASFAIVSAEECDPTDDICEIGVRMEEQLAKQLMMCKNTRDHHKAMGDVAGMNRFENLALTVQKDLDLVRYSKRKNEPLPKFHYEKRSFNIVHCNTDLTDSELEIVVVRGISYNVANPKDVDTYVRVEFPLLNDESFKTKTNVIRDTSSPDYDERFKVDIQRTNRQFQRIFKRHGVKFEIYSRGGFLRSDTLIGTVNVKLQPLETKCEIHDTYDLMDGRKQVGGKLEVKIRVRNPILTKQMEHITEKWLVLDA
What is the function of this protein?
Negative regulator of the Notch signaling pathway, acting to restrict the activity of Notch to the dorsoventral (D/V) boundary of the wing imaginal disk.  Also causes negative regulation of Notch during vein, eye, and bristle development.  Acts by targeting Notch for endosomal degradation or recycling.
What are the official names of this protein?
Coiled-coil and C2 domain-containing protein 1-like, Lethal giant disks protein.
What is the protein family that this protein belongs to?
Belongs to the CC2D1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_ECO27
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_STRSY
Sequence: MIFDKVNYKEFDKEVWEAIQAEEKRQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTECVDVVESLAIERAKEIFGAKFANVQPHSGSQANCAAYMALIEPGDTVMGMDLAAGGHLTHGASVSFSGQTYNFVAYNVDEETGLLDYDAILKQAKEVQPKLIVAGASAYARTIDFAKFREIADAVGAKLMVDMAHIAGLVAAGLHPNPVPHAHITTTTTHKTLRGPRGGLILTNDEELIKKINSAIFPGIQGGPLEHVIAAKAVSFKEVLDPAFKDYAQKVIENSKAMAEVFLANPNFKVITGGTDNHLFLVDVTKVVENGKVAQHLLDEVNITLNKNSIPYEKLSPFKTSGIRIGSAAITARGFGVEEARKVAQLTIKALENAENEKALEEVRQEVRALTDQFPLYEGL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKGC_DELLE
Sequence: MAVSARSARSPPDSDKVQKDKAGQTSGRRQGSRMGKLLGFEWTDVSSWGKLVTLLNRPTDPASLAVFRFLFGLMMVLDIPQERGLSSLDRRYLDGLEVCRFPLLDALQPLPLDWMYLVYTIMFLGALGMMLGLRYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANRYWSVDGLLSARKRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKFVLSEEMTSLLVVHWCGLLLDLSAGFLLFFDASRSIGLLFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSPEWPRKLVAHCPKRLQELLPLRTAPQPSASCVYKRSRAKGGQKPGLRHRLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQATWSPFQRTPWLQPLLMDLSPWRTKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLQEGEKMQLPAGEYHKVYTMSPSPSCYMYIYVNTTELALEQDLAYLQELKEKVENGSETEPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRLQEIERRRNAPFHERLLRFLLRKLYVFRRSFLMTCISLRNLVLGRPSLEQLAQEVTYANLRPFEPVGEPSPSNTDSSNPNPSEPNADAVHSEF
What is the function of this protein?
Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
What are the official names of this protein?
Vitamin K-dependent gamma-carboxylase, Gamma-glutamyl carboxylase, Peptidyl-glutamate 4-carboxylase, Vitamin K gamma glutamyl carboxylase.
What is the protein family that this protein belongs to?
Belongs to the vitamin K-dependent gamma-carboxylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.