PharMolix/UniProtQA huggingface dataset:
Protein: RL13_COXBU
Sequence: MATYMANAKTVSPRWLLVNAEGKTLGRLASRIAAILRGKHKAEFTPHVDAGDFVVVINVDKLKVTGNKTQDKQYHHHSGYPGGLKTINFADLQAKKPQRILELAIKGMLPKGPLGRQLYRKLKIYAGDQHPHQAQQPELIDL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SYE_MANSM
Sequence: MELKALFNLDPNVKVRTRFAPSPTGYLHVGGARTALYSWLYAKHNDGEFVLRIEDTDLERSTPEATAAILDAMEWLNLTWEHGPYFQTERFDRYNEVIDQMIEQGLAYRCYCSKERLEELRHQQEANKEKPRYDRHCLHDHEHSPYEPHVVRFKNPQEGSVVFEDAVRGRIEISNHELDDLIIRRSDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILKALGAPIPVYAHVSMINGDDGQKLSKRHGAVSVMQYRDEGYLPEALLNYLVRLGWGHGDQEIFTLEEMIKLFELEHVSKSASAFNTEKLLWLNQHYIRELPAEYVAQHLAWQYQEQGIDTSKGPALTEIVSMLGERCKTLKEMAASSRYFFEEFDGFDEAAAKKHLKAAAVEPLEKVKEKLTALSGWDAHSAHEAIEQTAAELEVGMGKVGMPLRVAVTGAGQSPSMDVTLAGIGRERVLARIQKAIDFIKAKNA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BURP0
Sequence: MITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGIRRVVMDALVTLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGIGDVFIRGERASAAEGLRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVKPFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCDKVQDPYSLRCQPQVMGACLDQIRHAAGVLLIEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHATSPALQHAMKTIRADVAHYDLDHYFAPDIAVVARRVRERAFATLSPLSFESEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_RHORT
Sequence: MTAPKSEFLAVVRDRGFIHQCTDLDGLDALLAKGPVSAYIGFDCTADSLHVGSLIQIMLLHWLQRTGHRPVVLMGGGTTRIGDPSFRDEARPLLTDEKIGQNMAGIRQVFSRFLSFGEGATDAVMVNNADWLDGLAYIPFLRDFGRHFSVNRMLTFDSVRLRLDREQPLSFLEFNYMILQAYDFLELGRRTGVRLQMGGSDQWGNIVNGVELGRRVDGLELFGLTSPLITTASGAKMGKTAQGAVWLNEARLPAYDYWQFWRNTEDADVGRFLRLFTDLPLDEVARLEALGGAEINEAKKILAERATTMAHGPEAALTAAETARKVFEQGGTGDALPTHDVAAEALAAGLPLAEMMRATGLAASGKEVKRLVSEGGARINDVAVSDAARLLGPADVQDGAIKLSAGKKRHALIRVLPG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_DESVV
Sequence: MSAPRTCYGIIPARYASSRFPGKPLADILGRPMFWHVYDRARRCAAFDEVALATDDARIADAANVLGVPCVMTAEHHPSGTDRVHEAAMRLGVADDAVVVNIQGDEPALDPRMLDQLVAPFADASVRVATLAMALSAQEAQSPDRVKVVVAANGDALYFSRADIPFVRDGDVGGDTAGRLGHIGLYAFRMEALRRFTQLPPSRLEQTEKLEQLRLLENGIAIRVVPTTYRTHGVDRPEDIDVIINLLRENDG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_SHIDS
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CITD_ECO81
Sequence: MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILEVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFRN2_DANRE
Sequence: MTADTSSGDAAVAGASAGAEIHWFGGRFWGVSESLVGTLTPRISGEPDLHVGHFYGSQEASDLSEPDYEGLPQGASTSTHMLAGAVAGIMEHCLMFPIDCVKTRMQSLQPEPAARYRNVMDALWRIMRTEGIWRPIRGLNITAVGAGPAHALYFACYERLKKVLSDIIHPGANSHLANGAAGCVATLLHDAAMNPTEVVKQRMQMYNSPYRSVLDCMRCVWQREGALAFYRSYTTQLTMNVPFQALHFMTYEYLQELLNPQRHYNPSSHMVSGALAGAIAAAATTPLDVCKTLLNTQESLAVDSVSRSGRHITGLGHAFRTVYRLGGLPAYFKGVQARVIYQMPSTAISWSVYEFFKYMITKHQHEKRRIQRDAEK
What is the function of this protein?
Mitochondrial iron transporter that mediates iron uptake.  Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells.
What are the official names of this protein?
Mitoferrin-2, Mitochondrial iron transporter 2, Solute carrier family 25 member 28.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYP_LEUMM
Sequence: MKQSKLLMPTLRDIPAEAEVKSHQLLLKAGYIRPIAAGMFSYLPLAKRVLNKIETIIREEMDKIDANEMLVPEVLPAELWQRSGRYETYGPALYKFKNRQDRDFILGPTHEETFTQLIADEIKSYKKLPLTVYQIQAKFRDENRPRFGLLRTREFIMKDAYSFSADQEGLDEAFHNMEEAYTNIFDRLGLEYRAIVGDAGAMGGSDSKEFSAPAAAGEDTIAYSDATDYAANLEMAKDFYERRSATAEQLALEKISTPNEKTIDDVATLLDKPKNELVKTIMFVADDELVAVVTTGDFEVNEVKVQNYLHADSLVMAEEADVRKAVGAGFGSLGPVGLPEEVKLLVDERAADLANFAAGANEDGMHYVNINWNRDVDLLAENVSDFRTVREGDLAIDGKGKLQFTSGIEIGHIFKLGTRYSKTLGAQVLDNNGRQTDVIMGSYGIGVSRLLSAIAEQKADEDGLVWPASVAPFDIHIVPINMKDEDQARVAEQLETLLVAQGMEVLVDDRKERAGVKFADADLIGLPIRITVGKKADEDVVEVKVRASNTNIEMRVSEVVDSVSVLLNASEK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_STRP6
Sequence: MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGVLGGFGGMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYIATGKNNPVKLEEVVSGVAEGCVQAGVALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKRLKDVLLEPTRIYVKAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKDLLDEPVYEIGRIIKKADDSVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_MARPO
Sequence: MAKSKDIRVTINLECINCAQNDEKRKKGISRYTTQKNRRNTPIRLELKKFCCYCNKHTIHKEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YOS3_SCHPO
Sequence: MISFSHWNSHIRSGLSLSMIPSANSRFAFIIQRNYIPVVNSQNTRWKRLCGTQSVWSPYKKKHVLVNRLKHISLFPKPIFARKFTTRQKSEDQKQWRILRITFLVLPFTVGGLWILYRVKNRKNNIFSFDELELEERSNRPRSIFGKIKQFFNILLRSFNLFIIFSPIIITLPFIALISFLHLRSLSSLTVSIWLRFLVTQLERAGATFIKLGQWAASRTDLFPPAFCKTLSKLHSHVTPHSLAYTQSVICKTYKVESIEEIFVNFNPIPIGVGAIAQVYTATIKKAATQQDNSYFTSMLQSIGFRQKNISDAPVTQDVAIKVLHPNVEKYISLDLQILGFFAKLINLVPSMKWLSLPDEVKVFGAMLNQQLNLHYEALHLNQFRLNFRGNRYVEFPAPYDDYTTNQILLEDYMPGIPLSAFLKHKSGPFNKLLANTGNNALFQMLIVDNFTHADLHPGNVLVKFYKGIPKTIFNQDNEINDSIYKILSTCSTEEWDSAMEELNILGYRPTLVFLDAGLVTKLSTQDQKNFLDLFQAVLTFHGYEAGLLMVERSRQTERVINKDIFALKMEHLLNEIQKSTLSLKSLQIGTILQEVMTMAREHHVRIEANFANTVLSILLVEGAGRQLYPEMDLLSNATPYLRSASSKSNVSLTNPMVQLWIALEARQFLLLSTSKETVEKWVKSDMIAPNI
What are the official names of this protein?
ABC1 family protein C21C3.03, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
Protein: C2CD2_MOUSE
Sequence: MGSWLSEVQWLFLVSLFVAALGTVGLYLAQWALAKARPPPRRRAEPDELRRRESDTLLSWILTRDSWGNQWQAAWVTALNYEAEKRGGPLRLSFQKDPRPQSLQLTVEKVSSVVKSTQEKVVICHVVGETLQFLVSAGPASATGSECQLYDVHLSPFHLKVEFHMEEKREDIQIRWSFTHVPETAIKIQPQAPGEKQALGVNMLSEALEDLFKHLVNAASPSVFLSTKPTQVKEAQSLQCPSSTAQEPCPPKPPRAHELKLQVKNIRVSLINHPGASGLSHVCVAQLNDPEQRFISTLVRNTTDLSWEEEFTFELNAKSKELVLQISQDGCSSEGLLGIATIHLDLFRKQPNGPQTFRLISGTEPDSLVLGSVTAEFSYVEPGELKSWPAPPPVSAAKIEKDRTVMPCGTVVTTVTAVKTKPRFDTGRATPLNSESPVRTPVTVKVIEKDISVQAISCHSAPVSKTFSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKTSLSQDHNAALMLDYAASMDSTNQGDATSALCHPEATEASATTPPEENEPAQTLPALKPRENDLDSWELEKESPVASWSGPALQEPDGDELSESSLSTSELGAMKKHKGGLLRKGAKLFFRRRHQQKDPGLSQSHNDLVFLQQPEGRQKKGATLGRLLNRKLLTRHRGKHTMNGVPREPCI
What are the official names of this protein?
C2 domain-containing protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GABT_MYCTU
Sequence: MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLDKQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAILADL
What are the official names of this protein?
4-aminobutyrate aminotransferase, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase, Glutamate:succinic semialdehyde transaminase, L-AIBAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: RS9_BRUSI
Sequence: MAESINSLEELGTVAKTEAAAPVHVQKLDAQGRAYATGKRKDAVARVWVKPGTGKITVNDKEFEKYFARPVLQMILQQPIVASNRAGQFDIVATVAGGGLSGQAGAVRHGISKALTYYEPGLRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ECPB_ECO45
Sequence: MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIQNSTDSGRLINIRLERLSSPLDDGQVIAMDKPDELLLTPASLLLPAQASEVIRFFYKGPADEKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLTNTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKFIPVK
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpB.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: ATPA_STRGC
Sequence: MAINAQEISALIKQQIENFQPDFDVTETGVVTYVGDGIARAHGLDNAMSGELLVFENGSYGMAQNLESNDVGIIILGDFTDIREGDTIRRTGKIMEVPVGEALIGRVVDPLGRPVDGLGEIATDKTRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLYLAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLSDGLFNGGVRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVVILYALTHGFLDSVPVDDILRFEEELFAYFDAHQEGIYETIRTTKDLPSEEVLDAAITEFVNQSSFK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATP6_SALHS
Sequence: MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SAT1_SCHPO
Sequence: MTECDVQMYMPVNVVQSGTDFECIVKFTNLRSSEDVNLLLCYASIHGEMYLDYVLVRVTEFDEVQRQGLLNKRTMSGLVHIPKVSSSYSVINTLNGMIGNLFGVKQASTLTEASEQKQENAIPVLLTRPDILGVDITLSPGEEKCFRLKRRIPLRTAPTYKGLAFRFQHALVIGVQSATNNACVEHEFEITIVPNVQQQPELPLGKNSGNRQSSKLFADLSKPIIETDAAEIEEVSAEKARRQFGKNGIRLSQDAQEEEKQKKKYEQHIKKLLDGESNEEGGGEFQDHGMRSEINEEVLEEEDEEKIALLKKLESKQPMATRFEITSKQKVLCRLLLSKSRYRTGEMMMIELEGLDAMVRQVHMQLESVERIVPDIRIRNSVGTERATRKVWCRITRGVFELENMSASMVVPEECPETFETQQFGVEHFLRVELLRAVNKKREMQGPAHPRYSEEVQSPSRSRYSEEVQRVSEGRLSEEVSKEEEKKGGRESGQHKRMASLTNSREMQIQHAPTTFAAETIQCVLPIRIEKRVVWMEDGMEGGMEGMQPV
What are the official names of this protein?
Protein sat1.
Protein: CITA_SALTI
Sequence: MAQHTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVRLSRGYIAAENKA
What is the function of this protein?
Uptake of citrate across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
Citrate-proton symporter, Citrate carrier protein, Citrate transporter, Citrate utilization determinant, Citrate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL25_STACT
Sequence: MASLKSIIRQGKQRRSDLTAIRNSGKVPAVMYGYGQKNVSVKVDEVEFIKVIREVGRNGVIDLGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVHLVGEAVGAKEGGVVDQPLFNLEVTATPENIPEYLEVEISGLEIGDSLSVADLNTTGDFTIENEPEATVVTVVPPTQGPSEAEIEEVEAGDADTPEPEVVGEKEEDEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ILVD_DESOH
Sequence: MKSDSMKEGLARAPHRSLLKSIGYTDEEIGRPIIGIVNSANEIVPGHADLNKIARAVKDGVYMAGGTPVEFSTIGVCDGIAMNHIGMKYSLGSRELIADSVEIMATAHAFDALVMIPNCDKIVPGMLMAAARLNLPTIFISGGPMLAGRYPGKPEKKVDLITVFEAVGAVKSGRMAPEELAIIEDAACPTCGSCSGMFTANSMNCLTEAIGMGLPGNGTVPAVMSERVRMAKQAGMRILDLLKNGVTPDKIMTAKAFRNALAVDMALGCSTNTVLHLPAIAHEAGVSISLDLINEISGIAPHLCSLSPAGPNHIEDLNMAGGIQAVLKELARKSGLIDPDCLTVTGRTVGENIASARDADGQVIRTLETPHHAQGGLAVLFGNLAPDGCVVKQSAVVDKMLVHEGPARVFDSEEDATTAIMDGRIKKGDVLVIRYEGPKGGPGMREMLTPTSALAGMGLDSTVALITDGRFSGGSRGAAIGHVSPEAMEGGPIAVVKEGDTITIDIPKKKIGLKLDAGEIQNRLSGWNRPAPKITRGYMARYADQVSSANTGAIFKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: YQGF_IDILO
Sequence: MSTVIGFDFGTKSIGVAVGQTITATASPLAAITAKEGIPDWQLIEKLFAEWQPEQLVVGLPLNMDGTEQPLTQKAKKFGNRLHGRFGLPVAFQDERLTSTSARESLFAEGGFRKLKKGAVDSQAALIIVEDFMNGYLPKSDNSL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APRIO_HUMAN
Sequence: MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE
What are the official names of this protein?
Alternative prion protein, AltPrP.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RISB_BACFR
Sequence: MKFGIVVSEWNANITGALLDGAVKTLKKHGAKEENILVKTVPGSFELTFGANQMMENSDIDAIIIIGCVIKGDTPHFDYVCMGVTQGVAQLNATGDIPVIYGLITTNTMEQAEDRAGGKLGNKGDECAITAIKMIDFVWSLNK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NAC69_ARATH
Sequence: MVKDLVGYRFYPTGEELINHYLKNKILGKTWLVDEAISEINICSYDPIYLPSLSKIKSDDPVWYFFCPKEYTSAKKKVTKRTTSSGYWKATGVDRKIKDKRGNRGEIGIKKTLVYYEGRVPKGVWTPWVMHEYHITCLPQDQRNYVICQVMYKGEDGDVPSGGNNSSEPSQSLVSDSNTVRATSPTALEFEKPGQENFFGMSVDDLGTPKNEQEDFSLWDVLDPDMLFSDNNNPTVHPQAPHLTPNDDEFLGGLRHVNREQVEYLFANEDFISRPTLSMTENRNDHRPKKALSGIIVDYSSDSNSDAESISATSYQGTSSPGDDSVGSSNRQFLQTGGDEILSSCNDLQTYGEPSISSSTRQSQLTRSIIRPKQEVKQDTSRAVDSDTSIDKESSMVKTEKKSWFITEEAMERNRNNPRYIYLMRMIIGFILLLALISNIISVLQNLNPAMKFDRER
What is the function of this protein?
Transcription activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP).  Involved in salt stress response during seed germination and seedling growth.  Binds the auxin-responsive IAA30 gene promoter and may serve as a molecular link that interconnects a developmental feedback loop of auxin signaling with a salt signal transduction pathway during seed germination (PubMed:21450938).
What are the official names of this protein?
NAC domain-containing protein 69, ANAC069, Protein NAC WITH TRANSMEMBRANE MOTIF 2, Protein NTM1-like 13.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Nucleus. Note=Localized primarily in plasma membrane or endoplasmic reticulum membrane as dormant form and, upon specific stress or signal, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Protein: VCCN1_ARATH
Sequence: MYQSMNLSVSSNFTHRSLLESRFPIFSTGFRKSVNLKPPRVSSGPESNDSGHETLTDKLIHLLRAVPDWADEIKERGMQQKRSLYTHEKWVEHRSSLRHVRHLLSSFSSRVILSLIPPVFFFTSVAVVIASYNSAVALDWLPGIFPILRSSSLPYQLTAPALALLLVFRTEASYSRYEEGRKAWVGIIAGTNDLARQVICSVDSSGDELIIKDLLLRYIAAFPVALKCHVIYGSDIARDLRNLIEADDLSLILQAKHRPRCVIEFISQSIQLLKLDDAKRDLLESKMLHLHEGIGVCEQLMGIPIPLSYTRLTSRFLVFWHLTLPIILWDECHWIVVPATFISAASLFCIEEVGVLIEEPFPMLALDELCDLVHSNIQEAVKSEKVIRNRIIAKIKLHEFKHSSNGRHRS
What is the function of this protein?
Voltage-dependent chloride (Cl) channel critical for proton motive force (PMF) partitioning across the thylakoid membrane by anion influx into the lumen during illumination, thus being required for photoprotection under fluctuating light conditions (PubMed:26947269, PubMed:27216227).  Influences thylakoid ultrastructure, including lumen size and organization (PubMed:26947269).  During photosynthetic response on transition from dark to low light, involved in a sequential mechanism of adaptation; VCCN1 and CLCe first trigger the activation of photoprotection, which is later down-regulated by KEA3 to a low steady state, while adjusting electron transport (PubMed:31201341).  On transition from low to high light, accelerates the activation of photoprotection by building up a pH gradient across the thylakoid membrane (PubMed:31201341).
What are the official names of this protein?
Voltage-dependent chloride channel 1, chloroplastic, AtVCCN1, BESTROPHIN-like protein 1, AtBest1.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Voltage-dependent chloride channel subfamily.
Protein: AADK_STAAU
Sequence: MRTEKEILNLVSEFAYQRSNVKIIALEGSRTNENIKKDKFQDYDFAFFVSDIEYFTHEESWLSLFGELLFIQKPEDMELFPPDLDYGYSYIMYFKDGIKMDITLINLKDLNRYFSDSDGLVKILVDKDNLVTQEIVPDDSNYWLKKPTEREFYDCCNEFWSVSTYVAKGVFRREILFALDHFNNILRPELLRMISWYIGFNRGFDFSLGKNYKFINKYLTDKEFNMLLATFEMNGYRKTYQSFKLCCELFKYYSNKVSCLGNYNYPNYEKNIENFIRNNYEN
What is the function of this protein?
Required for streptomycin resistance (PubMed:3357770).  Adenylates streptomycin on the O-6 residue (By similarity).
What are the official names of this protein?
Aminoglycoside 6-adenylyltransferase, AAD(6), Streptomycin 6-adenylyltransferase.
Protein: CAPP_PSEPF
Sequence: MTDIDARLREDVHLLGELLGNTIRDQYGEAFLDKIEQIRKGAKADRRGSMDAELSASLNQLSEDELLPVARAFNQFLNLANIAEQYQLIHRREETQAAPFESRVLPELLARLRNEGHSAESLARQLARLEIELVLTAHPTEVARRTLIQKYDAIAAQLAAQDHRDLTTAEREQIHNTLQRLIAEAWHTEEIRRTRPTPVDEAKWGFAVIEHSLWQAIPHHMRKADQALFAATGLRLPLEAAPIRFASWMGGDRDGNPNVTAAVTREVLLLARWMAADLYLRDVDHLAAELSMQQASDALKARAGDSAEPYRAVLKQLRERLRATRNWAHASLTATTPAPADVLHNNRDLLDPLELCFNSLHECGMGVIADGPLLDCLRRAVTFGLFLVRLDVRQDSSRHSAAMTEITDYLGLGKYEEWDEEQRISFLTRELQNRRPLLPAHFKPSADTAEVLATCKEIAAAPGASLGSYVISMAGAASDVLAVQLLLKESGVLRPMRVVPLFETLADLDNAGPVIERLLLLPGYRARLQGPQEVMIGYSDSAKDAGTTAAAWAQYRAQERLVEICREQQVELLLFHGRGGTVGRGGGPAHAAILSQPPGSVAGRFRTTEQGEMIRFKFGLPDIAEQNLNLYLAAVLEATLLPPPPPTPEWRHLMDELAADGVAAYRAVVRENPQFVEYFRQSTPEQELGRLPLGSRPAKRRAGGIESLRAIPWIFGWTQTRLMLPAWLGWETALSKALERGEGELLGQMREQWPFFRTRIDMLEMVLAKADADIALSYDERLVEPDLLPLGAHLRDLLSQACSVVLGLTGQSQLLAHSPDTLEFIRLRNTYLDPLHLLQAELLARSRRQNVEQGSPVEQALLVSVAGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.