PharMolix/UniProtQA huggingface dataset:
Protein: RBL_PYLLI
Sequence: MPEDVQNRTRIKSERYESGVIPYAKMGYWDADYNVKDTDILALFRITPQPGVDPVEARAAVAGESSTATWTVVWTDLLTACDIYRAKAYRVDPVPGTSDQFFAYIAYECDLFEEGSLANLTASIIGNVFGFKAVKALRLEDMRIPYAYLKTFQGPATGVVVERERLDKFGRPLLGATVKPKLGLSGKNYGRVVYEGLAGGLDFLKDDENINSQPFMRWKERFLYCMEGVNRAAAATGEVKGSYLNITAATMEQMYERAEYAHSIGSVIVMIDLVIGYTAIQSMAIWARKYEMILHLHRAGNSTYARQKNHGINFRVICKWMRMCGVDHIHAGTVVGKLEGDPLMVKGFYNSLLLTHLKINLAEGLFFDMDWAALRKCVPVASGGIHCGQMHQLLYYLGDDVVLQFGGGTIGHPDGIQSGATANRVALESMVLARNEGRDYVGEGPEILRRAAATCGPLKAALDLWKDITFDYTSTDTPDFVEVATESR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2190_MYCTO
Sequence: MRLDQRWLIARVIMRSAIGFFASFTVSSGVLAANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQLQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPGAPPAALPPGAPPGDGPAPGVAPPPGGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYAWGGAAPGGFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALSDLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
What are the official names of this protein?
Probable endopeptidase MT2245.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: RNFC_YERPB
Sequence: MFKLFTARQHDKIWDFDGGIHPPEMKLQSSTVPMRIAPLPDQLIIPLQQHLGPEGELRVRAGEQVLKGQPLTVGRGRTVPVHAPTSGMITAIAPHTTAHPSGLAELCVHITPDGEDRWREQQPWADYRQRDKMALLDRIHQAGIAGLGGAGFPTASKLQGGLNGIITLIINAAECEPYITADDRLMQEHADEVITGIHILRHLLQPQQVLIGIEDNKPEAIAALQRALRGQDDIHLRVVPTKYPSGGAKQLTKILTGKEVPFGKHSSSIGVLMQNVGTVVAIKRAVIDDEPLIERVVTLTGDALSSPGNFWARIGTPVLYLLKLAGFKPQNPPMVIMGGPLMGFTLPSLDVPIVKISNCILAPAETEMGLSEPEQSCIRCGLCVDACPAGLLPQQLYWFSRGEEHEKARNHNLFDCIECGACAYVCPSNIPLVQYYRQEKAEIRALDQESARAAEAKARFEAKQARLAREKLARELRHKQAAVKLTDADQQTVDAAVSRLTRQSDGSESVINIPAGQMPDNSAVIAAREARKAQARARQAEKQQARSTEETTDIVDPRQAAVAAAIARVKAKKAAQVQHVTTDVAEAGSEAIAEDPRKAAVAAAIARVKAKKAAQVQHVTTDVAEAGSEAMAEDPRKAAVAAAIARVKAKKAAQAINPD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DODA_MIRJA
Sequence: MKGTYYINHGDPLMYLKKHIKLRQFLEGWQENVVIEKPKSILIISAHWDTNVPTVNFVEHCDTIHDFDDYPDPLYQIQYRAPGAPNLAKKVEELLKESGMECEIDTKRGLDHAAWFPLMFMYPEANIPICELSVQPSKDGIHHYNVGKALSPLLQQGVLIIGSGGTVHPSDDTPHCPNGVAPWAIEFDNWLEDALLSGRYEDVNNFKKLAPNWEISHPGQEHLYPLHVALGAAGKNPKTQLIHRSWAANGVFGYSTYNFTPTTQKTD
What is the function of this protein?
Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.  Produces mainly (S)-betalamic acid.  Required for the coloration of flowers.
What are the official names of this protein?
4,5-DOPA dioxygenase extradiol, MjDOD, DOPA 4,5-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_CERS4
Sequence: MNILTPVAERLPSREEAEEALAVLRRWATHTPASDVAALAPEAPALVYPDLSRAYPRTFTVDEAYKASLPDLQNGPASLIVGAKAVIQHVGISNFRLPIRYHTRDNGDLQLETSVTGTVSLEAEKKGINMSRIMRSFYAHAEQAFSFEVIERALEDYKRDLESFDARIQMRFSFPVKVPSLRSGLTGWQYYDIALELVDRGGVRKEIMHLDFVYSSTCPCSLELSEHARRERGQLATPHSQRSVARISVEVRQGKCLWFEDLLDLVRSAVPTETQVMVKREDEQAFAELNAANPIFVEDAARSFCQALQSDPRIGDFRVVASHQESLHSHDAVSVLTEGPTFAAESLDPRLFSSLYHVG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: SECB_XANAC
Sequence: MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQRLNDNAFEVVLAVTLTCTAGGKTAYVAEVQQAGVFGLVGLDPQAIDVLLGTQCPNILFPYVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRQNEGTSLADSEPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_BRUA4
Sequence: MSLPDKAFPVSWDQFHRDARALAWRIAGMNRDWHAIVAITRGGLVPAAIVCRELGIRLIETVCIASYHDYTSQGDMQILKGVSETLLENGGEGVIVVDDLTDTGKTAAIVREMMPKAHFATVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIAGDKRG
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MNMA_STAAS
Sequence: MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTDA_PAPHA
Sequence: RCVCTRGFC
What is the function of this protein?
PhTD-1 and PhTD-3 have antimicrobial activity.  In low salt conditions PhTD-1 has antibacterial activity against the Gram-negative bacterium E. coli ML35p (MIC=1. 5 uM), the Gram-positive bacteria L. monocytogenes EGD (MIC=1. 6 uM) and methicillin-resistant S. aureus ATCC 33591 (MIC=2. 5 uM), and the fungus C. albicans 820 (MIC=1. 6 uM).  At high physiological salt concentrations the antimicrobial activity of PhTD-1 decreases slightly: E. coli ML35p (MIC=2. 0 uM), L. monocytogenes EGD (MIC=1. 7 uM), S. aureus ATCC 33591 (MIC=3. 6 uM), and C. albicans 820 (MIC=6. 5 uM).  In low salt conditions PhTD-3 has antibacterial activity against E. coli ML35p (MIC=1. 7 uM), L. monocytogenes EGD (MIC=1. 5 uM), S. aureus ATCC 33591 (MIC=1. 7 uM), and C. albicans 820 (MIC=1. 4 uM).  At high physiological salt concentrations the antimicrobial activity of PhTD-3 decreases slightly: E. coli ML35p (MIC=2. 2 uM), L. monocytogenes EGD (MIC=1. 9 uM), S. aureus ATCC 33591 (MIC=4. 5 uM), and C. albicans 820 (MIC=7. 4 uM).
What are the official names of this protein?
Theta defensin subunit A.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family. Theta subfamily.
Protein: ISPD_CALBD
Sequence: MKTCAILCAAGKGTRFGGNTPKQFLFLKNKMIIEYSLEVFEKSHFIDGIVLLVPQGFEDIARYLKDKFSKVIFWDYGGNERADTVKRGLEILKGECDIVAIHDSARPFITLELLEKLIADVETHFAVAPGILANDTVKFVVDGHIQNTLPRSNICLIQTPQVFKFDLIYRGYEMFKNELFTDDLQYVERLGIKPKIIENSRINFKITTKEDLLIAEAIVEKGYW
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: THIG_GEOSW
Sequence: MLKIGPYEFQSRLLLGTGKYPDLEVQKQAVEVSGAEILTFAVRRMNIFEPNQPNFLENLDLTKYKLLPNTAGAKTAEEAVRIARLAKASGLCDMIKVEVIGCEKTLLPDPVETLKATEILLEEGFIVLPYTSDDVVLAKRLQELGCHAVMPGASPIGSGQGIVNPLNLSLIIEQATVPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGAADPVKMAKAMKLAVEAGRLGYEAGRIPKKRYATASSPMEGMSVV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNSI_PETCR
Sequence: MAPTTITALAKEKTLNLDFVRDEDERPKVAYNQFSNEIPIISLAGLDDDSDGRRPEICRKIVKACEDWGIFQVVDHGIDSGLISEMTRLSREFFALPAEEKLEYDTTGGKRGGFTISTVLQGDDAMDWREFVTYFSYPINARDYSRWPKKPEGWRSTTEVYSEKLMVLGAKLLEVLSEAMGLEKGDLTKACVDMEQKVLINYYPTCPQPDLTLGVRRHTDPGTITILLQDMVGGLQATRDGGKTWITVQPVEGAFVVNLGDHGHYLSNGRFRNADHQAVVNSTSSRLSIATFQNPAQNAIVYPLKIREGEKAILDEAITYAEMYKKCMTKHIEVATRKKLAKEKRLQDEKAKLEMKSKSADENLA
What is the function of this protein?
Involved in the conversion of naringenin to apigenin.  Acts via a direct 2,3-desaturation of flavanones instead of a sequential hydroxylation/dehydratation mechanism.
What are the official names of this protein?
Flavone synthase, Flavone synthase I.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In contrast to the microsmal flavone synthase II, FNSI is a soluble enzyme.
Protein: ARLY_SALPA
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKETVRELLTANRLLQSALVETAQVNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAIDDARARLAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEP5_SCHPO
Sequence: MSTFIKNWKRITLFQVKAIEENIDRLTSSFSSNGELVVFATAFGDVSIYNSSFKSLQSIKVEDESSIQQILWLDNKTFLLFSNVEGGTGTNSTVIIYAFSQADENEPPQFVLVTTHKFSINESPYPIIAVSQSPIDKTIACGFGGGLVSCYHGNPLRERGIKNSYSHNLGEPITGLTYLDDQSSVLFIATTNKTYSLSGKSLSCLDNTGVSLNCSSSCKTTPLQSREKNSSSFVCTRSSGLTFYDSKREKICFTFPGEKHYMTVMGSILALCYTPTLGTDSSTNEGLKKSFSSSSSIRKADASRNPAFPPRLLLVDLSRNLIVWEGHLKDVAVSILPLKHGFLVVTADDNVFELKRITLQEEISLLCQKMMYNLAISLAKKENMDIEFRESLMRDYASFLFRRGDFSASMDWYIRSIKSIDIPSVCLEFLKAQEIKQLIRLLEELIKTGLATSDHRLLLLSCYVEIHDSPSIRKLIDIGEIDFDQAFKICYDSNLLDEAKHLAIRFNNNERVLDVLVESEQYSEALRFFESLPPSNLLPLLLKYGRVLLDKLPEKTTNIFIQFYSNSHRGDLSTSESKGELKTAKSLRQTYLSLLPYAQVANFSLPPSLYEISPSQEENQRAALFSEDVSYTAPSPQTCFHIFLNHNSELISFLEGILPNASPNYKTLINTCLFEAYIRESFASSNVEKQEFWQEKSNSLLKKVEKNVDLNAVFLISQILGFDDGVRFVQGKSGQTLDIFRSFCQQNDIERALKMVRVHGPDQQELYIMMLNCFASLENVDSWYQDINEIVNIIVSQRLISPTQLLDILGKSVNIKLEHISDSMQSVLDNYRESISKQNEAIEMGKRDIEEITSQLSILRTRAFVVQESKCSTCGIDLELPMVHFRCGHSYHQRCVEDECIRCRWL
What is the function of this protein?
Required for vacuolar biogenesis and for trafficking of hydrolase precursors to the vacuole.  Mediates transport at the vacuolar membrane where it may be responsible for tethering transport vesicles on the target membranes.  Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion.  HOPS is an effector for the vacuolar Rab GTPase ypt7 and is required for vacuolar SNARE complex assembly.  It remains bound to SNARE complexes after vacuole fusion.  Acts as component of the CORVET complex that is required for transport between endosome and vacuole.  CORVET is an effector for the endosomal Rab GTPase ypt5.  Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones.  Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase pep5, Carboxypeptidase Y-deficient protein 5, Histone E3 ligase pep5, RING-type E3 ubiquitin transferase pep5, Vacuolar protein sorting-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the VPS11 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: RS3_POLSJ
Sequence: MGQKINPTGFRLAVSRNWASRWYASNRDFAGMLAEDIKVREYLKAKLKNAAVSRVLIERPAKNARITIFSARPGVVIGKKGEDIENLKKELSRQLGVPVAVNIEEVRKPEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRLGALGIKIMSSGRLNGIEIARCEWYREGRVPLHTLRADIDYGTSEAKTTYGVIGVKVWVYKGDTLGRGESPGAKLDAAPSDEERKPRGPRRDARPGSDRPAPRGARAPRAPAGGTNTAPADGSDKPAEATPGSDAPKTTVKRVRKAAPAAAADGTKTE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PYRF_STAA8
Sequence: MKDLPIIALDFESKEKVNQFLDLFDESLFVKVGMELFYQEGPQLINEIKERGHDVFLDLKLHDIPNTVGKAMEGLAKLNVDLVNVHAAGGVKMMSEAIKGLRKHNQDTKIIAVTQLTSTTEDMLRHEQNIQTSIEEAVLNYAKLANAAGLDGVVCSPLESRMLTEKLGTSFLKVTPGIRPKGASQNDQHRITTPEEARQLGSTHIVVGRPITQSDNPVESYHKIKESWLV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: ACHA_CRORS
Sequence: AIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSKVAINAESEHPDLSNFMESGEWVIKEARGWKHWVFYACCPTTPYLDITYHF
What is the function of this protein?
Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RS3_ECOLC
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SCAF_BPPZA
Sequence: MPLEPEKHEEILNMLLDPELPQSERTEALQQLRVNYGSFVSEYNDLTKSHEKLAAEKDDLIVSNSKLFRQIGLTDKQEEDHKKADVSETITIEDLEGK
What is the function of this protein?
Scaffolding protein involved in the icosahedric procapsid assembly.  Coassembles with the capsid proteins to form the procapsid.  The scaffolding protein is found within the capsid as a serie of concentric shells.  During DNA packaging, the scaffolding protein molecules are released from the procapsid.
What are the official names of this protein?
Capsid assembly scaffolding protein, Gene product 7, gp7, Head morphogenesis protein, Protein p7, Scaffold protein.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus scaffolding protein family.
What are the subcellular locations of this protein?
Note=Present in about 147 copies in the prohead but not present in mature virions.
Protein: OPRJ_PSEAE
Sequence: MRKPAFGVSALLIALTLGACSMAPTYERPAAPVADSWSGAAAQRQGAAIDTLDWKSFIVDAELRRLVDMALDNNRSLRQTLLDIEAARAQYRIQRADRVPGLNAAATGNRQRQPADLSAGNRSEVASSYQVGLALPEYELDLFGRVKSLTDAALQQYLASEEAARAARIALVAEVSQAYLSYDGALRRLALTRQTLVSREYSFALIDQRRAAGAATALDYQEALGLVEQARAEQERNLRQKQQAFNALVLLLGSDDAAQAIPRSPGQRPKLLQDIAPGTPSELIERRPDILAAEHRLRARNADIGAARAAFFPRISLTGSFGTSSAEMSGLFDGGSRSWSFLPTLTLPIFDGGRNRANLSLAEARKDSAVAAYEGTIQTAFREVADALAASDTLRREEKALRALANSSNEALKLAKARYESGVDNHLRYLDAQRSSFLNEIAFIDGSTQRQIALVDLFRALGGGWDEGRSLVVHRGGRS
What is the function of this protein?
Channel-forming component of a multidrug resistance efflux pump.
What are the official names of this protein?
Outer membrane protein OprJ.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PYRC_ECOLC
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: YBAP_SHIFL
Sequence: MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHSHLIGSIHMGSHDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHISQEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEGAENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQSLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR
What are the official names of this protein?
Uncharacterized protein YbaP.
Protein: EB1C_ARATH
Sequence: MATNIGMMDSAYFVGRSEILAWINSTLQLNLSKVEEACSGAVHCQLMDSVHPGTVPMHKVNFDAKSEYEMIQNYKVLQDVFNKLKITKHIEVSKLVKGRPLDNLEFMQWMKKYCDSVNGGQHNYHALERREASKGGKEATKRAAATQQSGKSSSSSAPPRPSSSNGTRKHEPQSNNTGTHHSSTGNHHHSSKPSAKQSKPVPAYDEKITELKLYIDSLEKERDFYFSKLRDVEILCQNPDTEHLPLVGSIKRILYAADGEDVGAAETQTLSPIAEGSEERRNSVTESQKRKLIVNLDVDVAAITTLSPRQRLSDASDVKCSGSSPLLTC
What is the function of this protein?
Plant-specific EB1 subtype that functions preferentially at early stages of plant mitosis by regulating spindle positioning and chromosome segregation.  Accumulates in the prophase nucleus and is required to maintain spindle bipolarity during premetaphase and/or metaphase and for efficient segregation of chromosomes at anaphase.  May play a role in the dynamics of microtubule network in elongating pollen tubes.
What are the official names of this protein?
Microtubule-associated protein RP/EB family member 1C, APC-binding protein EB1C, End-binding protein 1C, AtEB1C, Protein ATEB1 homolog 1, AtEB1H1.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=During mitosis, accumulates in the prophase nucleus, and after the nuclear envelope disintegration is associated with whole spindle microtubules, plus end of microtubules, phragmoplast and finally is actively recruited to the nucleus. Localizes in the microtubule network in elongating pollen tubes.
Protein: GLK_YERPA
Sequence: MTTYALVGDVGGTNARLALCAVATGEILQAKTYSGLEYESLEDVIKQYLSEHQAKVTDACIAIACPITGDWVAMTNHTWAFSIAAMQQNLGLDHLEVINDFTAVSMAIPVLPAQDVLQFGGTQPQPGKPVAVYGAGTGLGVAHLVNVDRRWISLAGEGGHVDFAPNSEEEDQILAVLRQELGHVSAERVLSGPGLVNLYRAIVISDARLPEKLAPKDITARALADSCTDCRRALSLFCVIMGRFGGNLALNLSTFGGVYIAGGIVPRFMEFFKASGFRAAFEDKGRFKDFLQDIPVYMITHPQPGLLGAGAYLRQKLGYELSS
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_ECOL5
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPRPTQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVTDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANV
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: SPSB2_RAT
Sequence: MGQTALARGSSSTPSSHALYSDLSPPEGLEELLSAPPPDLGAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGLKGRTLYPSVSAVWGQCQVRIRYLGERRAEEPQSLLHLSRLCVRHALGDTRLGQISSLPLPPAMKRYLLYK
What is the function of this protein?
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (By similarity).  Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity).
What are the official names of this protein?
SPRY domain-containing SOCS box protein 2, SSB-2.
What is the protein family that this protein belongs to?
Belongs to the SPSB family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Note=Exhibits a diffuse cytosolic localization.
Protein: PUR7_CLOB1
Sequence: MEKKDMLYEGKAKKIFRTDDKDTVVVYYKDDATAFNGEKKGTIEDKGVMNNSITAMLFELLEKKGVKTHFIEKINEREQLCKKVEIVPLEVIVRNIAAGSMAKRLGLSEGRKLDTTVFEISYKNDDLNDPLINDYHAVAIGLTTFEELKEMYSIAEKVNNTLKEFFDEQGINLVDFKIEIGRFNGELLLADEISPDTCRLWDKSTGEKLDKDRFRRDMGNVKEAYMEILKRVNK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.