PharMolix/UniProtQA huggingface dataset:
Protein: GPMA_ECO7I
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RL14E_METJA
Sequence: MPAIEVGRVCIKTAGREAGKVCVIVDILDKNFVIVDGLVKRRRCNIKHLEPTEKKVDIPKGASTEEVKLALDAAGLLKEE
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: RRP36_HUMAN
Sequence: MPGANYRAGAGAGAGARRPRGARDREEDGGGLEPAAVARDLLRGTSNMSFEELLELQSQVGTKTYKQLVAGNSPKKQASRPPIQNACVADKHRPLEMSAKIRVPFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKHLSGEEHEKLQQLLQRMEQQEMAQQERKQQQELHLALKQERRAQAQQGHRPYFLKKSEQRQLALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHLPLSKE
What is the function of this protein?
Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA.
What are the official names of this protein?
Ribosomal RNA processing protein 36 homolog.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Concentrated in the fibrillar region of the nucleolus.
Protein: GATB_LEPBL
Sequence: MAEFETIIGLEVHAQLNTESKIFSTSATKFGSPPNSQTNPVCLGLPGALPVLNESALEKAIMAGIAFGCDISLFTKFDRKNYFYPDLPKGYQISQFDKPICTGGGVTFTIKGEESSRYVRLTRIHMEEDAGKLIHSADPNIPQSYVDLNRAGTPLIEIVSEPDMRSSDEAYYYLNSLKSILKYIRVSDCNMEEGSLRCDANVSIRPKGSDKFGTRVEIKNLNSFKAVKAAIDYEVEWQTEMALEGKTFQQQTKLWDSVANKTVTMRTKEMSHDYRYFPDPDLPVIILQKETVESVRSKLPELPNERKNRFVEKLGLPKYDAEVLTAEREIADYFEDALKVSGDAKKTSNWVKDEVLGVVNKESITISEFSVSAQRIGGLVKLIADGKISGKIAKTVFEELLISDKDAETIVTEKNLIVVRDDKEIERIVNEAIANNQDAVAKYKSGKDRALGAIVGYVMKVSKGKADPELVNQMLLDKLGSLPPKE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: HPRK_MYCMS
Sequence: MEKFTIKDLTDNLKFEIISGQDKLDTEIKSYGINRAGLELADYFKPFKDQSEWRATLMSTKESGYMLQFDEETKIKKYTQLMKCGIPVLIITNKFKDKTLIKVAKRLNFPLLRSDYPITIQLVQKIQDIYDIYFSPTAEEHAALMNIFGTGVLIKGKSGIGKSELCLDLIKHNHLFIGDDRIILTNKSNKIIGRVHPILKNLIEIRGIGIFDIVKSNGYQVIMNESPVELVVELVEYKEQNIDNSDRLGNDWSKFKILGVEIEHIQIPVSAGRSLVNIIESAVAQFKINKSKQFENVFDVIHKRTKEFLSSKK
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: IF1_VEREI
Sequence: MAKEELIEMQGSVTEVLPDSRFRVTLDNGHQLIAYTGGKMRKHHIRILAGDKVSLEMSPYDLSKGRITFRHLAGRGPGPSSSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG41_CAEEL
Sequence: MLSILPLAYSNFSRILQYFEQLPVVDKMTEEILKQGVGIVETSLTFEPPFCESFERISIDNFPIFALGKEISKEDGIEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDIEKTSEIYEKILQMFFDEKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIFDDWSNIAVHVALDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWRPLLLMIPLRLGLTTINPCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPKTESTAKMYAEKDSTATTDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLALAMFCETRDEFENLCETLQKTTLPASQPPMFEFLQRRPKYLPKFEPYTGVSMKIEMKEFDDIGAANVKIDDDFEVLDVHTEEEDADEDNDDDVANA
What is the function of this protein?
Cysteine protease required for autophagy (PubMed:22767594, PubMed:30880001).  Cleaves the C-terminal amino acid of ATG8 family proteins lgg-1, to reveal a C-terminal glycine (PubMed:22767594).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (Probable).  Its cleavage activity is functionally redundant to atg-4. 2, but it cleaves lgg-1 precursors more efficiently than atg-4. 2 (Probable).  Acts redundantly with atg-4. 2 to promote the lgg-1 delipidation to release the protein from membranes, which facilitates multiple events during macroautophagy (PubMed:22767594).  Unlike atg-4. 2 does not seem to be required for autophagosome maturation (PubMed:30880001).
What are the official names of this protein?
Cysteine protease atg-4.1, Autophagy-related protein 4 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCOB_HELPY
Sequence: MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGSVDADLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVKEKTEAEFEVRL
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B, OXCT B, Succinyl-CoA:3-oxoacid CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: IPYR_CHLT2
Sequence: MSKTPLSIAHPWHGPVLTRDDYESLCCYIEITPADSVKFELDKETGILKVDRPQKFSNFCPCLYGLLPKTYCGDLSGEYSGQQSNRENIKGDGDPLDICVLTEKNITQGNILLQARPIGGIRILDSEEADDKIIAVLEDDLVYGNIEDISECPGTVLDMIQHYFLTYKATPESLIQAKPAKIEIVGLYGKKEAQKVIRLAHEDYCNLFM
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB_OVIMU
Sequence: IIVTQTMKGLDIQKVAGTWHSLAMAASDISLLDAQSAPLRVYVEELKPTPEGNLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDNEALEKFDKALKALPMHIRLAFNPTQLEGQCHV
What is the function of this protein?
Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
What are the official names of this protein?
Beta-lactoglobulin, Beta-LG.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FURI1_XENLA
Sequence: MDLSPSLLLMLWTLLSVLVEEITGQKVYTNTWAAHISGGSAEADRLCKKYGFINHGLIFEDHYHFSHRAVMKRSLTPKRTRQVLLKREPQVHWLEQQVAKKRKKRDIYTDPTDPKFMQQWYLLDTNRHDLHVKEAWEQGFTGKGIVVSILDDGIEKNHPDLQANYDPAASYDVNDQDPDPQPRYTQLNDNRHGTRCAGEVAAVANNGICGVGIAYNANIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPAKLAEEAFYRGVTQGRGGLGSIYVWASGNGGREHDSCNCDGYTNSIYTLSISSTTQMGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTDSHTGTSASAPLAAGIIALALEANKNLTWRDMQHLVVQTSNPAGLNANDWITNGVGRKVSHSYGYGLLDAGAMVAMAKTWVTVGPQRKYVIDILSEPKDIGKALEVRRKVEPCAGMSNYISTLEHVQARLSLSYNCRGDLAIYLTSPMGTRSCLLAPRPHDYSADGFNDWSFMTTHSWDEDPAGEWVLEIENVSNNNNYGTLTQFVLVLYGTASEGLSRKFDGDGSRNVASSQSCIVCEEGYFLHQKSCIKSCPQGFTSSIQNIHYTLDNNIEPLLVNVCVPCHVSCATCKGTTINDCLTCPAHSHYNLLDYSCTHQTQRSRESPTLKDSSHDYVARTSNLPFIVAILSCLFIIVVFGSIFLFLQLRSGGVLGRKRLYMLDSGIISYKGIPSGAWQEEGFSESETEETAAHSERTAFLKQQSTL
What is the function of this protein?
Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif.
What are the official names of this protein?
Furin-1, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single- pass type I membrane protein. Secreted. Endosome membrane; Single-pass type I membrane protein. Note=Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin.
Protein: Y984_CAMJE
Sequence: MKILFSPSESKNENCVKNPINENSFIFKELFPYRMEALKHYEEFIKNASLQNLQELFGIKNENEIDKFKHDLKQAPTQEAILLYTGVSYEYLNFKALDKKSQAYILENTLIFSNLFGIVRANDTLPFYKFKQGAKIGNFAIEKFYKEHFSKALDEYLENEEILDLRAGFYDKFYTPKKKFYTYKFVKNGKVISHFAKAYRGILLSISAKNQVKNNKELLANLPSNLKLKEIQIKGLKEEIVLEILD
What are the official names of this protein?
Uncharacterized protein Cj0984.
Protein: MUTS_CLOBJ
Sequence: MGLTPMMRQYLEVKESCKDCILFFRLGDFYEMFFEDAKVASKELELVLTGRDCGLEERAPMCGIPYHAANTYIGRLVSAGYKIAICEQLEDPSASKGIVKRGIIKIITPGTYTDSSFLEENKNNYIMSFYLDDNMCAMSFADISTGEFNSTHSNFKEAVVLDEISKFAPREIVLEENIKESFIHTIKERFPNISISKIKEENFDYNIDNNLKEQFNNFNENEYETIVKKSANGLLYYIFHTQKNILSNINKIDYYSIVDYLTIDVNSRRNLEITENLREKTKKGSLLWVLDKTNTAMGGRQLRRWIEQPLINKNPIENRLNAVEELLNNISLQEDLKEDLKSIYDIERIVGKVASKSVNAKELISLKCSIGKVPYIKKYLSGFKSDLFLNMEQCIDTLEDIHKLLDKALLDNPSLSVKEGNIIKEGFNEEVDSLREAKSNGKKWIASLEQKEKEETGIKSLKVSYNKVFGYFIEITKANLNLVPEGRYIRKQTLSNAERYITPELKEMEEKILGAEEKLIDIEYKLFTEIRDFIEENIDRMQKTARIISDIDCLCSLATVALENNYIKPNINAKDEILIEEGRHPVVEKVIPKGEFISNDSLIDTKENQLILITGPNMAGKSTYMRQVALITIMAQIGSFVPAKKANISICDKIFTRIGASDDLAAGKSTFMVEMWEVSNILKNATSKSLVLLDEVGRGTSTYDGLSIAWSVIEYICNNKNLRCKTLFATHYHELTKLEDNIEGVKNYSVSVSELENEIVFLRKIIRGGADQSYGIEVAKLAGLPSPVINRAKEILQHIEGDKEENSLNIAPSKEYKSKDYIEVSKDTLNTKNNLGSEIKHDTLSETNTATIIEDESTKEHLSSNRKQINCRINDEKSIKKEVAVDSFQINFEYIKRDKIIEEIKNIDILNMTPMEGFNKLYDIINKTKDID
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MPSS2_TRYBB
Sequence: MGLPFLCHTRVCLFSNKIPFVLCGSRFAPATLHAHHTAAGGGETLNFPELSSPSTSKEPSVGSDSPQKKNKKQAFDALARWCGGHQQLLMRIQQSAEDTSAGVVFETPLTEVDSAAIRWLQGSTEQLTCGQSLLVCSFVCEVLYCQLNSASGGIGVEEAQRLQIHALTNRIAALLQRADESNKLESQPLSVLMSCAYVVQRLKYVDNPLFGETQRSLVKVPPSIMFALLHKLRGDGLGKLFQLDERTATDVCLSFLFIATEEHRQAFFSSGDAALVSNVLRRLVRYTASKTRRMRIQKEGDIIDLLTVDSPSDGGARQTPVCTSGTGFTSPSMRECAMIMQNVSFSSPSNRLELLLYLLCVRRNLAQCSLKDIELVPTVLSTVANIRSAEACSIRKKIISQLWLPENNPTLVAQLLVHSGESIPRYVTYLQGVPASKLSPRDAAQVILCAGTYLSYESLQLYIMAALRDIMPSSSLVTLGAETTSASVPATASVPTRVPACDSLETVLSVLLMRVEEKGGSLSEVEKDACMEYIRRLNELIDWCASAPTSSPKPALQRLTLLTKLFNRGLVVHAPETVVELAVQSLQLDPGNTMMNTLKCVSEALPLVSDDKKRSIIIEKMISYSGTRTTSSVIRFLLLLAPLVDADSPHSCELVEQLLKFHTLNPHKLRQASVEGVAKGIDVYTLLLINGIDFLLASGDWRSSPSQLQNVITTWVRDYTLYVMDPARKQKIDDGAAAHVAPATKGEKTDVVQHQQPSRLNEGGELPTLSGPNDEELEQVFTCLLRAGVKLPHAFSSELLSRIRRLQAKRNPADGTDQQVVFPLPAHFVFCCKLDVPVEVSVTPEMMKYHIDACDYRIIHCVITAFFSAAGTFKHNINDLLLCNMRLASRSFELFIQRLGEEASRSFRPATVSSVVANTLRFVVNHITKQERCQRVLRKLNEKGGIEAGEEELEGDRSLIAEHTRLGELLTRMIAYLSGAHVKNVGLSVLDRLSLLSPACGEYLMMRLSTQLSEFTQVELLYLVQKYPKSQDLVAELLGKSDLVSSMDFGDYMRVMRNLPMPINALVIGAHLPGLNFQWCTRILSSLSVRHESVPLHLLASVLRRLNDVTESATLTDRNIAFVVLQKYLQFDQTSGDGGDLEERQRLIKCSCDKLLVLSRINSLDTLKEFLVEFPEALSGVICESLSKHVVQHIVGGLLKDLDGLLTLCRLLHRHKLLTSDVKVAIVDGFFMKTLQSEVEGRANIEGESSQGLQPLNSVRGASLKTTHPVSNVLALALLLSDGPLHFPGASNSSSTICGDNERCAVSSMFQVVKESYTSPRDRLLIANTLVGQKGPNALTVVAKEICTELIENCESVTSNDFSRLLQCISRLKCWSELDLANSRFDEVFQRSCTQADAHSRCVAFRAVSFEADIFRRYESFMIPLLQETVDVMSNEDLETVLSSVLSLPFTEALESLIDAIGTRLLRMIDQCRRSALIRLLQCHAAFGIQDDALVSVCVATLTDQCGRDFRLDTAQVLALLQAAVDLDFFLPPKLVTSCFTWLEHHVENMTITQLGHAVRLAVDVEVGYTAAVHTLTLRALEQRDAIRSNASFREAVEMLCDEFSAEIPWHLRAPVLRRRYQSERLLEYLDKRRLAVDSTVA
What is the function of this protein?
As part of the mitochondrial 3' processome (MPsome), involved in the maturation of guided RNA (gRNA) precursors.
What are the official names of this protein?
Mitochondrial 3' processome subunit 2.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EIF1_PONAB
Sequence: MSAIQNLHSFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGF
What is the function of this protein?
Necessary for scanning and involved in initiation site selection.  Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 1, eIF1, Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: CLSA_PECAS
Sequence: MSTFYTVISWLLVFSYWLLIAGVTLRILMKRRAVPSAMAWLLVIYILPLVGIVAYLSFGELHLGKRRAERASKMWPSTAKWLRELKEYRRIFATENSEVASALFQLCERRQGVGGVKGNQLQLMTTFDDTIKALLRDIELARNNIEMVFYIWQPGGLVEQVTSSLISAARRGVHCRILLDSAGSVQFFRQHHPELMRTAGIEVVEALKVNLFRAFLRRMDLRQHRKIILIDSRIAYTGSMNMVDPRLFKQDAGVGQWIDLMARIEGPVATTLGIIYCCDWEMETGKRLLPPPPDVNVMPFEQESGHTIQVIASGPGYPEEMIHQALLTSVYSARKQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPHKNDSVLVGWASRAFFTELLAAGVKIYQFKDGLLHTKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDAGFGSDLACVQEDYIARSRLLNATQWQNRPYWQRIVERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_BURCJ
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIGRGQRELIIGDRQCGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAASASDSAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRDNLKTSHADLIKRIEDTKDLSKDDEGALRSAIEAFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSUB_BACC1
Sequence: MTVSIDGVSKYFSKQTRTVQVLENINFQLEKGDFVTVIGPSGCGKSTLLKIIAGLDGEFEGEIIIDGERITKPSKKQGFIFQEHRLFPWLTVEENIAADLSLKDKYVKDKVKEWVEIVRLDGFEKSYPKEISGGMSQRVAIARALLRDPNVLLLDEPFGALDAFTRSHLQEVLLNIWEQKKTTMIFVTHDIDEAIYLSNRIVIMSAKPGKIHKVIENNLPYPRSKTSESFQEIRKKVLQQFERGGLIQTSI
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1615_GRAFK
Sequence: MVRLIVIFLIIAIIAAIFGFGGVAEGAADIAKIIFYIFLVLLVISVLSRLFRK
What are the official names of this protein?
UPF0391 membrane protein GFO_1615.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2298_ALKCK
Sequence: MASLTLEEIETMLDDMKKKLNVVNASVITSDSVSPAKHDDLIALHAHVMRSPSFSISEMDEIVQELGQLRGRKS
What are the official names of this protein?
UPF0435 protein ABC2298.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: METK_HERAR
Sequence: MANDFLFTSESVSEGHPDKVADQISDAILDAIFQQDPKARVAAETLCNTGLVVLAGEITTFANVDYIEVARDTIKRIGYDNADYGIDYKSCSVLVAYDKQSPDIAQGVDEGAGIDLDQGAGDQGLMFGYACDETPELMPAAIHYAHRIVERQSELRKDGRLPWLRPDAKSQVTLRYVDGRPVSIDTIVLSTQHAPEMQHKDIEEAVIESIIKPVVPAEWLKDTRFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERAQIQISYAIGVAKPTSVMVTTFGTGKISDEKIAQLVLEHFDLRPKGIVQMLDLLRPIYQKTAAYGHFGREEPEFTWERTDKAAALRAAASL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_CHOCR
Sequence: MNNILNFYPAVITTDVAENWQIGFQDPATPIMEGIINLHYDLMFFICVISVFVSWMLGRTLWHFEQNQNKIPSSLTHGTLIEMIWTVTPAFILLIIAVPSFSLLYAMDEIISPAITIKTLGHQWYWSYEYSDYLNEDDDSINYDSYMIPEEDLEIGQFRLLEVDNRMVIPINTHIRVIVTAADVLHSWAVPSFRSKCDAIPGRLNQTSLFIKREGVYYGQCSEICGINHGFMPIVVEATSLPNYVSWISNKLNE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ERPA_SHIBS
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CCMA_PSEF5
Sequence: MTSPLLEAVALACERDWRMLFEHLELRLTGGDMVQISGPNGSGKTSLLRLLAGLMQPTSGQVLLNGQPLHAQRAELARNLLWIGHAAGIKELLSPEENLSWLCALHQPARREAIWQALAAVGLRGFEDVPCHTLSAGQQRRVALARLYLDSPPLWILDEPFTALDKQGVAQLEEHLAGHCERGGMVVLTTHHSLARMPSGYRDIDLGRWAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EFTS_SALHS
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKGADEELVKQLAMHVAASKPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.