PharMolix/UniProtQA huggingface dataset:
Protein: EFG_RICBE
Sequence: MSKKLENIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKQINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVDMIKDRLGAKPLVIQLPIGIEENFKGVVDLVKMQAVVWKDESLGAEYSYQEIPDDMKAKAEEYRANLLDMVVELDDKIMEKYLSGEEVTEEEIKKLIRKGTISAAFYPVLCGSAFKNKGVQPLLDAVVDYLPSPIDIATVKGVEVSTGEEKDFPISVSEPFSALAFKIMNDPFVGSLTFIRVYSGKITSGTTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDEDKKVILERMEFPEPVIELAVEPKSKVDQEKMGLALSRLAAEDPSFRTSTDQETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKACEIDYTHKKQSGGAGQFARVKIIFEPLKDVKDLKEEDKNKSFIFESKIVGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLIDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMKVEVITPDEYMGDVIGDLNSRRGQVQGMEPRGNAQVIKAYVPLAEMFGYVNTLRSLSQGRAQYSMVFNHYDQVPTQVADTIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHPT_MYTSE
Sequence: KLSYDDKVFENVEFTPRL
What is the function of this protein?
Hormone that controls sex pheromone production in larvae.
What are the official names of this protein?
Pheromonotropin, Pss-PT.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPZ_SYNP6
Sequence: MAEYYALQRQLLQVTLICTVVIFGAVWWAYSLNTAASYLLGAMGGLLYLRMLGKAVERIGERRRQFGKSRLALFVVLIVLAARWQYLELMPVFLGFLTYKAALIWYTLRAVIPTAENS
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FETUA_BOVIN
Sequence: MKSFVLLFCLAQLWGCHSIPLDPVAGYKEPACDDPDTEQAALAAVDYINKHLPRGYKHTLNQIDSVKVWPRRPTGEVYDIEIDTLETTCHVLDPTPLANCSVRQQTQHAVEGDCDIHVLKQDGQFSVLFTKCDSSPDSAEDVRKLCPDCPLLAPLNDSRVVHAVEVALATFNAESNGSYLQLVEISRAQFVPLPVSVSVEFAVAATDCIAKEVVDPTKCNLLAEKQYGFCKGSVIQKALGGEDVRVTCTLFQTQPVIPQPQPDGAEAEAPSAVPDAAGPTPSAAGPPVASVVVGPSVVAVPLPLHRAHYDLRHTFSGVASVESSSGEAFHVGKTPIVGQPSIPGGPVRLCPGRIRYFKI
What is the function of this protein?
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone.  Suggested to have lymphocyte stimulating properties, lipid binding capability and to bind thyroid hormone.
What are the official names of this protein?
Alpha-2-HS-glycoprotein, Asialofetuin, Fetuin-A.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_PARPJ
Sequence: MDKTQSRLRRARQTRIKIAELQVARLAVHRTNTHIYAQVFSPCGTKVLASASTLEAEVRAQLADQTGKGGNVNAATLIGKRIAEKAKAAGIESVAFDRSGFRYHGRVKALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: APD1_ARATH
Sequence: MDSAPSPSSLDFELSPPVLVTMTSTSSSASDNVEGADDDANTHGIFNWRDFSSCWRVSESNLYCFSLALLIWFFASFILIENLYGPKNVWLGPSSSILVEPSSIFVKSIKVKVLDYSEPGLQLYGFYRTPALDCFVNWSESRVLSISHESYKGWPYYLNSGSLLNITYTVKPQGSAVQLVVDEGHQGVPQSVLNDPAYRYNVWSWNLIEGSGMIQLEIRKSSSYYLAVANLKSKDVEVELNIDVKAVLYDTKQSFYNCNFSNGECTFNAMSLVGNSVVVTSPAASQGVSIEDEWYIRFSYQPREIAYVIGTGVVICFMLVAIQFCNRFQCSGGEGHLTEDDSARTRLLADKDDDGSSMGSCDDSYANDDADLEEFMGNDGEASNRSRRLCAICFDVPRDCFFLPCGHSVSCYECGTTMQEADGSCPICRRKMKKVKRIYTV
What is the function of this protein?
Involved in pollen mitosis II (PMII) regulation during male gametogenesis.
What are the official names of this protein?
E3 ubiquitin-protein ligase APD1, Protein ABERRANT POLLEN DEVELOPMENT 1.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein. Note=Associated with intracellular membranes and in the tonoplast and endosomes in the germinating pollen tubes.
Protein: PUR5_SHEPW
Sequence: MSTPTTPLSYKDAGVDIDAGNALVNNIKSAVKRTRRPEVMGNLGGFGALCELPTKYKHPVLVSGTDGVGTKLRLAIDYKKHDNVGVDLVAMCSNDLIVSGAEPLFFLDYYATGKLDVEVATAVVKGIAEGCVQSGCALIGGETAEMPGMYEGDDYDLAGFCVGVAEKEEIIDGTKVQDGDALIALASSGPHSNGFSLIRKVLEVSKADPEQELAGKPLIDHLLEPTKIYVKSLLKLIEEHDVHAMSHITGGGFWENIPRVLPEDCKAVVKSDSWQWPVVFNWLMEKGNISEFEMYRTFNCGVGMVVALPADKVESALNLLNAEGEKAWLIGDIAKRSGDEEQVEIL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_CYAP4
Sequence: MTEVEKKISFDGRDIHITIGRFAPQAGGTVMIRSGDTAVLVTATRAAAREGIDFLPLLVDYEERLYAAGRIPGGFLRREGRPPEKATLISRLIDRPLRPLFPGWLRDDIQVVATTLSMDEQVPPDVLAVTGASVAVLLAQIPFNGPMAAVRVGLVGDDFIINPTYSEIEAGDLDLVVAGSPAGVVMVEAGANQLPEQDVIEAIDFGYEAVRDLIRAQQELLTELGIALVQQDPPPRDPTLENFIRERAEAPVKEILARFEKDKNVRDAALDEVKAAIEQAIKELEETDPVRVAAALDAKALSNTFKEVTKTLMRRQVIEGNVRVDGRKLDEVRPISCLVGVLPRRVHGSALFNRGLTQVLSAVTLGTPGDAQELDDLHPDESKRYLHHYNFPPFSVGETRPMRSPGRREIGHGALAERALVPVLPPQDQFPYVIRVVSEVLSSNGSTSMGSVCGSTLSLMDAGVPLTKPVSGAAMGLIKEGDEVRILTDIQGIEDFLGDMDFKVAGTDSGITALQMDMKITGLSLQVVAEAIQQAKPARMHILEKMLETLSQPRQETSPFAPRLVNLKIDPELIGLVIGPGGKTVKGITEETGAKIDIEDSGMITISASDEDKAKRARSIIMGMTRKLSAGDVYVGKVTRIIPIGAFVEFLPGKEGMIHISQLADYRVNKVEDEVSVGDEVIVKVREIDGRGRINLTRLGIHPDEAAAARAAVAS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1382_COXB1
Sequence: MDRRLLEILACPICKGKLVYSQDEQELICRFDKLAYPIHDGIPVMLPDSTRPLIER
What are the official names of this protein?
UPF0434 protein CbuK_1382.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: LHPL4_BOVIN
Sequence: MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSGAFKAAAFFVLLSMVLILGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKQENKDFVGSTVSSVLRPGGDVSGWGVLPCPVAHTQGP
What is the function of this protein?
Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites.  Acts in concert with NLGN2 to recruit or stabilize GABAARs.
What are the official names of this protein?
LHFPL tetraspan subfamily member 4 protein, Lipoma HMGIC fusion partner-like 4 protein.
What is the protein family that this protein belongs to?
Belongs to the LHFP family.
What are the subcellular locations of this protein?
Cell projection, dendrite. Postsynaptic cell membrane; Multi-pass membrane protein. Note=Specifically localizes to inhibitory postsynaptic sites (By similarity). Colocalizes with GPHN, GABRG2 and NLGN2 at inhibitory postsynaptic sites (By similarity).
Protein: SYL_MYCSJ
Sequence: MTETPTAQPDRAADADTPQHRYTAELAGQIEGAWQQTWAVEGTFNVPNPVGELAPPDGTVPADKMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDTRRSFSTTDVDFYTWTQWIFLQIYNAWFDRDANRARPIAELIGEFESGVRTLDDGRPWSELSAGERADVVDSYRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDLEVLDWPDKVKTMQRNWIGRSTGASVQFGTDAGDIEVFTTRPDTLFGATYLVLAPEHPLVEQLAAEQWPDDVDGRWTFGATTPREAVAAYRASIAAKSDLERQENKTKTGAFLGAYATNPANGQQVPIFIADYVLIGYGTGAIMAVPGHDQRDWEFAHEFGLPVVEVISGGDISEAAYAGDGLLVNSDYLDGLDVAAAKAAITDRLVADGRGRARVEYKLRDWLFARQRYWGEPFPIVYDSDGRPHPLPESALPVELPDVPDYSPVLFDPDDADSEPNPPLNKATDWVHVELDLGDGLQTYTRDTNVMPQWAGSSWYELRYTDPLNKEALCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEVVERDGKFWFEGAEVFQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVDEQSGAVRVANHEALDTDTLRALHRTVAGVSEDYAALRNNTAAAKLIEYTNHLTKEGVTARAAIEPLVLMVAPLAPHLAEELWRRLGHDTSLAHGPFPVADPQYLVTDTVEYPVQVNGKVRSRITVDADAGKDTLEAAALADEKVQAFLNGATPKKVIVVPGRLVNLVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSTB_DICDI
Sequence: MSELSESGSYNSYNSLSAGSPLPLQEIFNGAETKCQSHYLQSRINTNYEQVKQQLKESAEKKNSSKIYSSLQHLTYYKVEKDLLETILRIIDITDDKKTLRLAYYFLGEISQFKHLINNSTEIKNITTIFNKEMQHKDISRKVVSLKTTASVAPNDVLIDANILDVISGILRKVGEDPDKTQKKKGFFTRATTDLGRERSLLQYSCFVACRNRYKNNPSLFMPIVEGIKCVDPVGARHAVSLTLNYALENPSTVAATTKRFIPLLKANKGKEAVYLVDPFARRNFIKLCGHLAATPSPIGNVITMENKDFFQSLCQSVMDAHLSVAFYAINVLSRFSWPTLESAHIDAIQFDSELPHFESLAFQTSLIVGICNKMRIGFNTYSIGAYSNYSMQHGHHHLHHYHQGGSGTVGGSVPSSSSSSSSSSNITTSALSSGSSSNSSLSSQQLLLVQQQQQQLLHQQSNPFLHLACKLISVLSQSYVKYSYPKDSTTQQPIIGDWSFDEKQYQHQSVYPYHHNLSPFTGLPNPISNNNNSSNNTKDQSTTTTTSTTSSSSNSIHPFSSLTQLILNLLNISPSISIRIQALKALVWLCPSNLDQSKLYLETFRSQLRDPYHPTHLFKELFLELYKRIIATPILSPMILELVYDWIDIIPSKCDTSLVCEIWKTIVEFGKVFANEKLLASIFKILDRIVHPDFRVLAMEIQKDIIKFLGEYSNQITFEQPSRFEQCKSRSGSNQQQHLSNMSLNSIIQRLQQYSIFSPWQIRLESIDSLAKIAFQSSTVVKVHIYNFLTLLPNESHGWTTVKSNTSIIVNTLDQLLTCRAKWLPLFKSSDLSQNQIKDLKNDHTNLCLQIGLFFDQLSFDYLPLGIESKKYLGSK
What are the official names of this protein?
TSET complex member tstB, Protein TSAUCER.
Protein: COX4_BACSU
Sequence: MVDKKSRGHINSDLEFKKKKHAREMKYQVLSFGLMIGLTIVAFLTVATDGVGSWFTIPFIILLAAIQVIFQLYYFMHMNQKGHEAPALFLYSGVFVAFITVLAFVTIIWW
What are the official names of this protein?
Cytochrome c oxidase subunit 4B, Caa-3605 subunit 4B, Cytochrome aa3 subunit 4B, Cytochrome c oxidase polypeptide IVB.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EMBC_MYCTU
Sequence: MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVATDLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAHADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVALTGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAATVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGTAAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGWWYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEVVSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVMERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRAPLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIALTPPRIPRVRTLQNVVGAADPVFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLMRATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase C.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEF_ALBFT
Sequence: MNTPQNSPLGQATAYLDQYDASLLFPIARATKRAEIGVTGALPFLGADMWTAFELSWLNLRGKPQVALARFTVPCESPNIIESKSFKLYLNSFNNTRFADVDAVKARLRADLSEAVWRDAGKNVSPDAAAPPSIGVTLLLPELFDREPIYELDGLSLDRLDVECTHYTPAPDLLRVVPDEAPVSEVLVSNLLKSNCPVTGQPDWASVQISYSGAPIDQEGLLQYLVSFRNHNEFHEQCVERIFMDLWTRCKPVRLAVYARYTRRGGLDINPFRTSYAQALPANVRNARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ACIC1
Sequence: MGAVILDGRAVAADILAELTERVGRLRGQGVLPGLGTVLVGDDPASHAYVAGKHRDCAKVGIASIERTLPASASQAEVAAVIDELNADPACTGYIVQLPLPAGLDEVAVLERMDPAKDADGLHPVNLGRLVLMRPGPLPCTPRGCLELLRRYEVPIAGADVVVIGRGITVGRALGLLLTRRSENATVTTCHTGTKDLAAHVRRADIVVAAAGVPGLVTPDIVKPGAAVLDVGITRVIGDDGRARYTGDVHPDVREVAGWLAPMPGGVGPMTRAMLLANVVEAAERQAGFPAAS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HPSE2_MOUSE
Sequence: MRVLCAFPEAMASSSSRPPSCLALVALFLALLLHLSLSFHAGNRRPLPVDRATGLKEKTLILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRTDFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREKASQMHLVLLKEQYSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSSALSLLKYSASKKYNISWELGNEPNNYRSIHGRAVNGSQLGKDYIQLKSLLQPIRVYSRASLYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQIRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIRHSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRIYAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSVQLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
What is the function of this protein?
Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity.  Inhibits HPSE, possibly by competing for its substrates (in vitro) (By similarity).
What are the official names of this protein?
Inactive heparanase-2, Hpa2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 79 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: OXLAA_CERCE
Sequence: MNVFFMFSLLFLAALESCADDKNPLEEEFFEADYEEFLLIAKNGLQQTSNPKRVVIVGAGMSGLSAAYVLAKTGHEVILLEASERVGGRVSTYRNDQEGWYANLGPMRLPERHRIVREYIRKFGLQLNEFSQENENAWYFIKNIRKRVGEVNKDPGVLEYPVKPSEKGKSAPQLYRDSLQKIIEEYGRSNCSYILNKYDTYSTKDYLIKEGNLSPGAVDMVGDLLNEDSGYYVSFIESLKPDDIFAYENRFDEIVGGFDKLPTSMYQAIQEKVRLNVRVIKIQQDVKEVTVTYQTPAKNLSYVTADYVIVCTTSGAARRIKFEPPLPLKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIHGGKSITDRPSRLIHYPNHNFPNGIGVLVIFTIADDADFFLALDNKTIADIVIHDLSLIHQLPKEKIRDLCYVSMIQKWSLDKYAMGGITTFTPYQFQHFSEALTAPVDRIYFAGEYTAQAHGWIDSTIKSGLTAARDVNRASENPSGIHLSNDNEL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:25009089).  Is highly active on L-Met>L-Leu>L-Phe>L-Trp=L-Ile (PubMed:25009089).  Binds to the cell surface and enables the production of highly localized concentration of hydrogen peroxide in or near the binding interfaces (PubMed:26433175).  Does not bind to phospholipids (PubMed:26433175).  Induces platelet-rich plasma aggregation, shows cytotoxic effects on some cancer cell lines (B16-F10 (mouse melanoma), PC12 (rat pheochromocytoma), MCF-7 and MDA-MB-231 (human breast carcinoma)) and shows antibacterial activities against both Gram-positive and Gram-negative bacteria (PubMed:26433175).  Also exhibits hemorrhage and edema (By similarity).  Does not show cytotoxicity on erythrocytes and peripheral blood mononuclear cells (PubMed:26433175).  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino acid oxidase, CC-LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TFAM_MOUSE
Sequence: MALFRGMWSVLKALGRTGVEMCAGCGGRIPSSISLVCIPKCFSSMGSYPKKPMSSYLRFSTEQLPKFKAKHPDAKLSELVRKIAALWRELPEAEKKVYEADFKAEWKAYKEAVSKYKEQLTPSQLMGMEKEARQRRLKKKALVKRRELILLGKPKRPRSAYNIYVSESFQEAKDDSAQGKLKLVNEAWKNLSPEEKQAYIQLAKDDRIRYDNEMKSWEEQMAEVGRSDLIRRSVKRSGDISEH
What is the function of this protein?
May also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis.
What are the official names of this protein?
Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. SUBCELLULAR LOCATION: [Isoform Nuclear]: Nucleus.
Protein: NDK_ALBFT
Sequence: MTVERTLSIIKPDAVAKNVIGQIYARFEAAGLKVVAAKMAHLSAREAQAFYAVHKDRPFFKDLVDFMISGPVMIQALEGENAVLKNRDLMGATDPKKAAPGTIRADFADSIDANAVHGSDAAETAAVEIAFFFPGMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEG2_HUMAN
Sequence: MTGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE
What is the function of this protein?
This protein binds beta-galactoside.  Its physiological function is not yet known.
What are the official names of this protein?
Galectin-2, Gal-2, Beta-galactoside-binding lectin L-14-II, HL14, Lactose-binding lectin 2, S-Lac lectin 2.
Protein: SYDE_DROME
Sequence: MQWKKKFTRLKAATGNSRVRRMLCCGRRKENGRSVPDVTASPGRAPPGPLPANQMPAMGNQQHHGNQQHHGNQQQHHGNQHSNHRGQSGSLSNAAGVKDPVMLQGDFRKVSGISSEIFRQIEAVENDHDPNTAAALEAVERRGEMIVRVLEPRCMGSKQAVDAAHKLMNKADARHTVQLVEIVKRPGQTLGLYIREGNGADRTDGVFISRIALESAVYNSGCLRVGDEILAVNLVDVTHMSLDDVVIIMSIPRRLVLAIRQRRGNRGTGSPGPPTLSRPEQKPPPVVVIKRDLRDEDLDETDRMPRPRSSRDRRTGDGREMTESRSRLGLGLNNYSPQSEQLDMYYNTRGGGGGAMGEPPNWGYKPPPPPSSVITEQPTKAHAFAPSHAYYQNAGTLESLAEKVHAFYPGQPGGPPVGPSRRMSTGTGNVGLAQQHARFPRSGSDQHLPRVEYSDYSNSLGRHSLLRSSLKPGTTGGAPMQVGVGGTLGRYGRYDQQRAGVSKYGPPSGGAQSLTRRSRPNLDYSSDTEATIGPRPSYYYYNRPAIGSMSRGSGGAGGGVGAASTAALLAGAADLNKFNSLPRERPGTRLQGIRSRMGDRLVDENDGNTSAPEFDVRRGRDLRQRITASPSIFTADEYRAWLRRAPSSSAIAEQMRMTRDMFAQPRAQRFSCSAENIHDALRNTESIYSSRNHILGTGTLDRNMGLTRPISALPVRSMSSQHIGGAGSIRSPSIRRMRQLLELSAGPASPSGSILSTGGHQSPAPTPSATLPRPHRQIDINPAEFAKYKLDKPIVDIGGISGMLWIHLLAGRGLRTAPEGAAGTATQGQTRDLYCVIECDRVHKARTVVRSGDLQFDWDESFELDLVGNKQLDVLVYSWDPQHRHKLCYRGAISLSSILRQSPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTLFGADLETVVNRESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVPDINVITGVLKDYLRELPEPLFTRCLFQMTVDALAVCLPDDPEGNAKLMLSILDCLPRANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLMLHSASAQPGADIDHAQPIAVLKYLLQIWPQPQAQHQQMAQHMGGAAGAMMGGLVTAGSMSNMAGVASGRRGESTGQRGSKVSALPADRQQLLLQQQAQLMAAGNLLRSSTSVTNILSQGHPQLSATANNHLYQSVVGQLAQSHRALQQAVQQPYQLGGSVGSAIPDPSPLPLPGTPSPGSSSASTGSGSGSGKSTDTIKRGASPVSVKQVKIVDQPSSPYSIVMKKPPLQKDAPVEITTPTTQADTESTLGCKESNGTASRRGNVDFYDTHKTQAKSVVNEESSYSSKYTGSETKKIIPGNSSYTPSKANASGLSGGEDYKAMRNKSSATSSSSSSQATVLSAGSTATSAPTTSSDDSDDLVSYKSSASTNALLAQSQAMTTSQLMSKYLKREPRVQFTPIKSPESPSPPGSGDGLPKGTYQLVTPISGSSSKPGATTGAISKYTTGSVESSINANSQKLSSPSRLCNSKDSNSRTGTASSTTPATSMVSTGRRLFDSLASSSSSETETKTYIGGTTAASGAITTTIYTNDTKNSGSSSSKSGIGGGSGTGLGAVSGASSETRSFGSTLFGSSGLGNGNGSSHNHSSASPSPFTTTNGNGNHNTMHLYGTLPKNGTSTGAALFGGSANSSSYHSSASGSGAGTASSSGVSSMTGSTNSYDFYTSTSSTVSSSRPFANGGNNYHTLGTYRAQYAATNPFLDAFDEKPGSNGGNAHGEEKLGADKGHHRAAVMAFQSSGDSKNGSDEYDDIK
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 100F, RhoGAP-100F, Synapse defective protein 1 homolog, Protein syd-1 homolog.
Protein: ENV_HV1YF
Sequence: MGMKSGWLLFYLLVSLIKVIGSEQHWVTVYYGVPVWREAETTLFCASDAKAHSTEAHNIWATQACVPTDPNPQEVLLPNVTEKFNMWENKMADQMQEDIISLWEQSLKPCVKLTPLCVTMLCNDSYGEERNNTNMTTREPDIGYKQMKNCSFNATTELTDKKKQVYSLFYVEDVVPINAYNKTYRLINCNTTAVTQACPKTSFEPIPIHYCAPPGFAIMKCNEGNFSGNGSCTNVSTVQCTHGIKPVISTQLILNGSLNTDGIVIRNDSHSNLLVQWNETVPINCTRPGNNTGGQVQIGPAMTFYNIEKIVGDIRQAYCNVSKELWEPMWNRTREEIKKILGKNNITFRARERNEGDLEVTHLMFNCRGEFFYCNTSKLFNEELLNETGEPITLPCRIRQIVNLWTRVGKGIYAPPIRGVLNCTSNITGLVLEYSGGPDTKETIVYPSGGNMVNLWRQELYKYKVVSIEPIGVAPGKAKRRTVSREKRAAFGLGALFLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNILLRAIEAQQHLLQLSIWGIKQLQAKVLAIERYLRDQQILSLWGCSGKTICYTTVPWNETWSNNTSYDTIWNNLTWQQWDEKVRNYSGVIFGLIEQAQEQQNTNEKSLLELDQWDSLWSWFGITKWLWYIKIAIMIVAGIVGIRIISIVITIIARVRQGYSPLSLQTLIPTARGPDRPEETEGGVGEQDRGRSVRLVSGFSALVWEDLRNLLIFLYHRLTDSLLILRRTLELLGQSLSRGLQLLNELRTHLWGILAYWGKELRDSAISLLNTTAIVVAEGTDRIIELAQRIGRGILHIPRRIRQGLERALI
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.