PharMolix/UniProtQA huggingface dataset:
Protein: RF1_LEPBL
Sequence: MIDRLEKIQEKYLRISEELNSAKDPSSLKSLYKERSRLTPLYLKVEEYLKIYKDKKDAEELIPSEKDEEMHSMLKEEIRRASKKLEELEKELEILLLTPDPNSGKNILVEIRAGTGGEEAGLFVADLFRMYSKFADKQKIKSEIIDSAPTGIGGLKEIIFALEDERAYDLFKFEGGTHRVQRIPSTESGGRIHTSAVTVAVLPEADEEEIEINENDLRIDVYRSSGAGGQHVNTTDSAVRITHIPTGVVVACQDEKSQHKNKAKALRILSARILEKQTEDKKQASDAIKKQMIGSGDRSERVRTYNFPQGRCTDHRIGFTSHNLSAIMEGDLEELIGALTEEDRARKISETQVH
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_RIPO1
Sequence: MPLPIVAIIGRPNVGKSTLANRLAGDQHAIVHDEPGITRDRTYRPGFWQDRDFQIVDTGGLVFDDDTEFLPLIREQSLAALNEASAAIFVVDGQTGPTTGDLEIADWLRQQPVPVLLAVNKCESPELGLIQATQFWELGLGNPYPISGIHGNGTGELLDDLITYLPPPEEITQSDEIKVAIIGRPNVGKSSLLNALLGENRAIVSPISGTTRDAIDTVIQHNEQTYRLIDTAGIRRKKNVEYGAEFFSINRAFKAIRRCDVVLFVIDAIDGVTDQDLKLADRIIEEGRSVVLVINKWDAVDKDSYTIYEYKTNIFSRLYFMEWAPIIFVSAMTGQRVNKILELVNSSTEEHRRRVTTAVINEVLQEAVTWHSPPTTRQGKQGKIYYGTQVSTQPPTIALFVNDPKRFNENYRRYIESQFRKQLGFPGTPIRLLWRGKKVREVEQSANRATKV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ARCC2_STAAS
Sequence: MKEKIVIALGGNAIQTKEATAEAQQTAIRRAMQNLKPLFDSPARIVISHGNGPQIGSLLIQQAKSNSDTTPAMPLDTCGAMSQGMIGYWLETEINRILTEMNSDRTVGTIVTRVEVDKDDPRFNNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYRKVVASPLPQSILEHQLIRTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASEKLATLIEADTLMILTNVENVFINFNEPNQQQIDDIDVATLKKYAAQGKFAEGSMLPKIEAAIRFVESGENKKVIITNLEQAYEALIGNKGTHIHM
What are the official names of this protein?
Carbamate kinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFEU_ASPOR
Sequence: MKLLTVAFSLLLLGQVHASPLVLDKRSSCQLGDVWDLNAADAACSASCAIQHGDKHGGHCDKNKVCVCN
What is the function of this protein?
Shows antibacterial activity against numerous Gram-positive bacteria (Probable).  It selectively inhibits peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis (PubMed:20508130).
What are the official names of this protein?
Fungal defensin oryzeasin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: GRA1_POGPU
Sequence: FIGGIISFFKRLF
What is the function of this protein?
Has lytic and hemolytic activities.  Its hemolytic activity is inhibited by phospholipids, but not by cholesterol.  Has antibacterial activity with a broad spectrum against various species of bacteria including both Gram-positive and Gram-negative groups.  Has ichthyotoxic activity.
What are the official names of this protein?
Grammistin Pp 1.
What is the protein family that this protein belongs to?
Belongs to the grammistin family. Group 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4191_MYCPA
Sequence: MTSTRYEGDTWDLASSVGVTATMVAAARAMATRADNPLINDLFAEPLVKAVGVDLLSRLAGGELDPAELNDVHDGAAGSAGAMSRMADNMAVRTKFFDEFFLNATKAGIAQVVILASGLDARAYRLAWPAGTVVYEVDQPQVIDFKTTALAQLGAAPTAERRVVAVDLRDDWPAALRAAGFDPARPTAWSAEGLLGYLPPEAQDRLLDTITELSAPGSRLATESAPNPAPGEEEKLKERMQAISQRWRAHGFDLDMAGLVYFGERNEAAPYLAGHGWRLNSVTIRDLFAANGLDPLDDDDTRMGEMLYTWGIYE
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4191c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: RL22_YERPN
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALETLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MURC_PARD8
Sequence: MDINKVTAVYFVGAGGIGMSALIRYFLAKGKRVGGYDKTPSDLTEELKKEGADIHYEDNVALIGEAFKSPDDTLVVYTPAVPESHTELTYFRAHGFEVMKRARVLGEITKSSRGLCVAGTHGKTTTSSMLAHLLKQSPVDCNAFLGGILKNYESNLMLSDTSDFTVIEADEFDRSFHWLTPYMAVITSADPDHLDIYGTAEAYRESFEKFTSLIRPDGCLLIKKGINVTPRLQEGVKKYTYSVTEIADFYAENIRICDGNITFDFVGPEIRIPDVELGVPVKVNIENGVAAMAIAWLNGVKPEDLKKGMATFAGPRRRFDFHLKTDQVVLIDDYAHHPAELRQSILSVKELYAGRKVTGIFQPHLYTRTRDFAGDFAASLSLLDELILLDIYPAREEPIPGVSSRIIFDKVTIPSKTLCKKEELLDVVAAGKYEVVLMVGAGNIDRLVEPVKEILCKQIRKP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_GOSHI
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: URED1_METPB
Sequence: MALSLDDLPEKPAPAEPVSAPVGRRVQASLVFARGGGTTVLSRQVVPYPFHITRAFRMHPESPDLATLYLQSASGGLYAADHLTLDIAARPGARVHVTTQAGTVVHRGGPEPTRQDTRLAIAADAFLALNPDPLILFPGAHLAVSTDITAEPGARAIVTESVACHDPLGQDRPFDRLDLGLTIRTPEGRALVRERSRIDGAAFVGPDSPMGGHRAYGTMVVLGAPEDARLAGPLLRQASDTAGCLTGVSVLPNGAGLGLRLLAPDGGTLSAGMEAVFRIVFEALSGCGPGRRRK
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_ACIAC
Sequence: MHIDLNSDLGESLGAWRMGDDAAMLGIVTSANVACGFHAGDAAGILATLRGAKERGVAVGAHVAYRDLAGFGRRNMDVASADLVADVIYQIGALQGLATAAGTRVTYVKPHGALYNTIARDARQARDVIAAIRAIDASLALVVLAGSPLERWAADAGLRVVAEAFADRAYTPQGTLVSRREPGAVLHDAGEVARRMLQLVREGTVRAIDGSTTRVRADSICVHGDSPGAVDMARAVRGALEREGIALRPFA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: DNJB9_CRIGR
Sequence: MATPQSVFVFAICILMITELILASKSYYDILGVPKSASERQIKKAFHKLAMKYHPDKNKSPDAEAKFREIAEAYETLSDAHRRKEYDTVGHTAFTNGKGQRGSGSPFEQSFNFNFDDLFKDFNLFGQNQNTRSKKHFENHFQTHQDGSNRQRHHFQEFSFGGGLFDDMFEDMEKMFSFSGFDTTNRHTVQTENRFHGSSKHCRTVTQRRGNMVTTYTDCSGQ
What is the function of this protein?
Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (PubMed:29198525).  J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (PubMed:29198525).  In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (PubMed:29198525).  Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (By similarity).  Required for survival of B-cell progenitors and normal antibody production (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily B member 9, Endoplasmic reticulum DNA J domain-containing protein 4, ER-resident protein ERdj4, ERdj4.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MQO_MYCTA
Sequence: MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: OSR1_XENTR
Sequence: MGSKTLPAPVPIHPSLQLTNYSFLQAFNGLPVPAEHMPNLYGFSALHAVHLHQWTLGYPTLHLPRSSFSKVPGVSSLVDSRFQIPTFPLFPHMIHPKQESPNLSNKTKPRFDFANLALAATQEDHCKLGQMDDQGSPPTIGGLLDVTKLTPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHTQVKELKPSKIKC
What is the function of this protein?
Transcriptional repressor (By similarity).  Required for pronephric kidney development.
What are the official names of this protein?
Protein odd-skipped-related 1, XOsr1.
What is the protein family that this protein belongs to?
Belongs to the Odd C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_SALDC
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSNLKGVLQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDDTMTYRYREEKGFFASVVIDNNTFTGRHLKALEEREFPDVDTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKMKKD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL34_MYCPU
Sequence: MSKRTYQPNKRKHAKTHGFRARMATKKGRLVLASRRAKGRKQLTVSDK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PANC_XYLFM
Sequence: MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADMRGLENVGCDVLWLPSVETMYPLGTERTVRLFVPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQVDYAVIRLSDLGEPIDGIVISPGIALVAARLGNTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG6_ASPOR
Sequence: MDLENNTIHCSTFVQHTYIKLNPVGPIGAGRLPETRSVEEAQQYPTGWKFWLTILTMSALVVLGGLDTNIVATAVPSHASTRTPSPAASPLSPPATQRSSALTNRLTSVLSASYADSDIRDALETLSLRDIHNTPEVRRQLRLDVQKEVVDCNAEIVRDFGKVAEQLKRIGTVITSLNQTCDEMRKHISLARQDTAPVLEEASTLMNQKKEAETKQQLLDAFTKHFVVPDDDILVLTSLEDPINDQFFEVLARVKQVHRDCEALLGGENQRLGLELMDKSSRNLNSAYQKLYRWIQKEFKSLNLEDPRISSSIRRALRVLAERPSLFHSCLDFFAEARDYTLSDAFHYALTDAVSGTAGDSNVKPIEFSAHDPLRYIGDMLAWVHSTTVSEREALEALFVADGEELARGIQAGLSSEPWSRIDEHEEVAFDGQKALSDLVNRDLIGVSRALRQRVELVIQGHDDPVTCYKVVGLLSFYRTTFQKLLGPNSNLAELLVTLEKFTFGHFEALMKDVVSSLSTDHLALTPSEDLSTPQFLIDALEGLTSLMKTYEASFGADDTESTSDENRFTPVLRAAFDPFLELATSSAEELSNATARAIYLTNIHLTARTSVSEYSFVSTTHLNPISTKLSSLRIDLLEIQHRYLLDESGLQVLLTALEPFSPSSVAKSSTETEKQDSHPLESQPQQQPNLADIATLPAFQPEALIAVSQQLDDFLPSALMDATDNLKRLRSAAFVKSVTEEAVEAFCRDFEFVEGMIIGADEARGKVDVTRVDRGSETGAESEKGMEEGENGWGLRRLFPRTTGEIRVLLS
What is the function of this protein?
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: DHMA2_MYCBO
Sequence: MSIDFTPDPQLYPFESRWFDSSRGRIHYVDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSERPSGFGYQIDEHARVIGEFVDHLGLDRYLSMGQDWGGPISMAVAVERADRVRGVVLGNTWFWPADTLAMKAFSRVMSSPPVQYAILRRNFFVERLIPAGTEHRPSSAVMAHYRAVQPNAAARRGVAEMPKQILAARPLLARLAREVPATLGTKPTLLIWGMKDVAFRPKTIIPRLSATFPDHVLVELPNAKHFIQEDAPDRIAAAIIERFG
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase 2.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: HTPX_SHELP
Sequence: MKRIFLLIATNMAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDNMERWLVDTVARQAEQAGIKMPEVAIYQSPELNAFATGPSKDNSLVAVSSGLLYGMTQDEIEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVASIIDNFVASNDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRVREFKADAGGAQLAGKHKMIAALDRLRQGPETGAMPAQMAAFGINGKKSMAELMMSHPPLEKRIEALRAQ
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASTD_IDILO
Sequence: MTNSIQFIDGCWEAGEGQLFKSIDPARNEVIWSGEAASETQVEKAILAARAAFPDWSGRSVEERLAICQKFSELLEENKEHLARTMAKETGKPVWETRTEVGAMMGKVAISERAYHERTGTVENDMPGAKAFIRHKPHGVVAVYGPYNFPGHLPNGHIVPALIAGNTVVFKPSELTPMVAQETVKLWEKAGIPAGVLNLVQGEVDTGKALSAHPQIDGLYFTGSSNTGHLLHKQFGGRPDKILALEMGGNNPLLVTNVADVDAAVHNIVQSAFITSGQRCTCARRLFIEDSEQGRAVLERLIEVTENILVDDYEADPQPFMGAMISAKAAGEMVDAQNELLHKGAKSLVRMKQTDSKKGFVTPGIVDVTGVEDLPDEEHFGPLLKVYRFKDIDAAIKEANNTRYGLSAGVLCDDEQTYRYFFKHIRAGIVNWNKPITGASSAAPFGGIGASGNHRASAYYAADYCAYPVASVEADSMSLPESLAPGLKF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: DNAK_AKKM8
Sequence: MAKILGIDLGTTNSCMAVMEGGQGTVLENSEGARTTPSIVAFTKSGERLVGQAAKRQAVTNPKNTVFSSKRLIGRKYSELTEEDKKVPYEIVEAPNGDAYIRVDVGGEKKTFSPQEIASMVLAKLKADAESKLGETITEAVITVPAYFNDAQRNATKAAGEIAGLKVRRIINEPTAAALAYGLDKKSNENIAVYDLGGGTFDISVLEIGDGVFEVKASDGDTHLGGDDWDNAIINWIIGEFKKDSGMDLSNQPDAIQRIKEEAEKAKIALSSTQSYDISLPFITADASGPKHIQLTLSRPKLEQLTEDLLDRTRKPVLDCIAASGLKTGDIDELVLVGGMTRMPAVQEMAHTLAGKEPHKGVNPDEVVALGAAIQGGVLQGDVNDVLLLDVTPLTLSIETMGGIATPMIERNTTIPVRKSQVFSTAADNQPAVDIRICQGERKMFEDNKLLGNFKLDGISPAPRGVPQIEVTFDIDANGILHVSAKDKGTGKEQKISIQGSSGLSKDEIERAKRDAEAHAEEDKKRAEEIDTINQADSLCFSVERQLKDMGDKLPADLKREIEDKVTRLKEAVSKKDVTAIKAGKEDLESRLEALYKAAEAAQQSAGAAGPMPGAPAEEEPSDGPRKAKGRVVDAEIVDDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YAGK_ECOLI
Sequence: MKTYQGTHGVHILEYQSKINKLLCYLTNRYPRLIAVRVDLHYPKIVDNGDNICCFPNLEPGVISRMRESLRAKLEADRTRKVREDKRIYRCPLFIIWAKEYSESGKCHYHICLLFNKDAYYHLGDYDQDDNLRGMITGAWYSALRLERDDHPGLVHFPENCKYVLDTNSTDFQQNYQALLTRLDYLTKVESKVFGEGDRNFGCSQIEL
What are the official names of this protein?
Uncharacterized protein YagK.
What is the protein family that this protein belongs to?
To E.coli YfjJ.
Protein: H2AA1_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKSNICVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1s, U4-TRTX-Hhn1s, Hainantoxin-II-27, HNTX-II-27.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COX5A_OTOCR
Sequence: MLGTALRRCAVAAASRAGSRGLLHPTPVPGPTAAIQSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: UPPP_CERS5
Sequence: MTDSTTLVALVLGLLEGLTEFIPVSSTGHLLLAGHFLGFESAGRSFEVVIQLGAVLAVLTVYASKLISVIRAAPRDPQAARFLAAVLLAFLPAVVVGVMAHGFIKTVLFETPILIAIMLILGGIILLFVDRMAPAPRYNDVTEVPLGVALKIGFFQCLAMVPGVSRSGATIVGALLLGTGKRAAAEFSFFLSMPTMAGAFAFDLYKNRDVLDAGALGEIAVGFVAAFLAAVLVVRWLLGYVSRHGYSLFGWWRIIVGSIALAALLKGF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPXH_STAHJ
Sequence: MAEELKIVDNRSREDANLSPVNKIEIYSFFDPFNTDCFKLSAIISKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSDFDNIALAYKAAELQGRLRAERFIHLMQNEIIPKKDIITEEMICDCIINAGLDYNEFKEDLQKSKLTESLKIDLHIAREMEIEQAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGTPIEKNLPPKIEHYIQKKQLVTTEELLTIYEWPEKLMTKELKKLALQQKVEKLQYPEGDFWQSKMPRI
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SALRD
Sequence: MLVLGIESSCDDTAAAVWDDGTVRSNVVSSQADLHEEYGGVVPELASRNHQRLIVPVVQRALAEADADARALDAIAGTYGPGLPGSLLVGLSFAKALAQGLDVPLIGVNHLEGHVYSVDLGPERPARPFLCLIVSGGHTELVHVGDDFQHDVLGRTRDDAAGEAFDKMAQLFGLGYPGGPDIDRHAESGAPTFHDFPRSRLDDFDFSFSGLKTSVLYYLRDRSDADRERLLDEHLDDLCASVRAAVVDVLVDAVRRAVEATGVGHVAVVGGVAANSALRRRMKALGDDEGVDVSVPDLAYCMDNAAMIAQAGARRLAAGHASPPTLDVHPSLQL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I82A3
Sequence: MLSITILFLLIAEGSSQNYTGNPVICLGHHAVSNGTMVKTLTDDQVEVVTAQELVESQHLSELCPSPLKLVDGQTCDIINAALGSPGCDRLDGAEWDVFIERPTAVDTCYPFDVPDYQSLRSILANNGKFEFIAEEFQWSTVKQNGDSGTCKRGNVNGFFRQLNWLTKSNGDAYPLQNLTKANDGDYARLYIWGVHHPSTDTEQTNLYKNNPGRVTVSTKTSQTSVVPNIGSRPWVRGQSGRISFYWTIVEPGDLIVFNTIGNLIAPRGHYKLNSQKKSTILNTAVPIGSCTSKCHTDRGSISTTKPFQNISRISIGDCPKYVKQGSLKLATGMRNIPEKATRGLFGAIAGFIENGWQGLIDGWYGFRHQNAEGTGTAADLKSTQAAIDQINGKLNRLIEKTSEKYHQIEKEFEQVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDVTDSEMNKLFERVRRQLRENAEDKGNGCFEIFHQCDNKCIESIRNGTYDHDIYRDEAINNRFQIQGVKLTQGYKDIILWISFSISCFLLVALLLAFILWACQKGNIRCQICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: Y261_STRP3
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein SpyM3_0261.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.