PharMolix/UniProtQA huggingface dataset:
Protein: RPOC2_MARPO
Sequence: MAEPVNLIFYNKVMDRTAIKQLISRLIAHFGITYTTHILDQLKTLGFQQATFGAISLGIDDLLTAPSKSWLIEDAEQYGNLSEKHHNYGSLHAVEKLRQLIETWYATSEYLKQEMNPNFRITDPLNPVHMMSFSGARGSTSQVHQLVGMRGLMSDPQGQIIDLPIQSNFREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRKVDCGTLYGINVNNLSEKKNNFQQKLIGRVIAENIYIDHRCIAPRNQDIGALLANRLITLKTKQIFLRSPLTCKSMNWICQLCYGWSLSHGNLIEMGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGDIAEHVRTPFNGIIEFNENFVYPTRTRHGHPAWMCHTNLFLVIKSKNKVHNLTIPPKSLLLVQNNQYVESKQVIAEIRAKTSPFKEKVQKYIYSNLEGEMHWSTKVRHASEYIHSNIHLILKTCHIWILSGNFHKKNNDLSVLFYKNQDKIDFPISLTKEKNEFSFVKNKTQLNLFLFHFYLYKKNKIFIKSQLTNNILNKINNSKNYNFILQEYNIKKKKNFYFLKNKNLTCPLFLKIKKNGVLKNNEIFAILDDPSYKVKNSGILKYGNIKVDLINQNTNFEDPQTKLFRPRYSIIKEGNFFFIPEEVYVLTQSLSSVFIKNNKFIQAGTLITSNIRSNTNGLVKIQKKGNNNYELKILPGTIYYPNETYKISKQISILIPPGKKLFNEFECKNWTYLQWIMPSKEKPFVLIRPAVEYKISKKLNKSTLFDLLKKNKKVEIKTINYLLYEDDEQIQIINEKNIQLIQTCLLVHWKKKYFFKEANVSFLKIKTKNNFKTFLQISLIEYSNLEKKKEKTISKNVLKKNYYDHFFSISKNELKNKKQGVIRIISNQNNGMQSFIILSSSDLVKTFKFKKLTKNISIKTNTNTSTAKFFEFNKNFKILNKKKKLNLTKKNFSIGLLLFKKLGFLGNLHNIVTNSFSSFYLINYTKLISNKYSIITKFQHTCQNPKWYLIDESKKINKLILGKHINYNLFNWCFPLFSLLKKKIDFQTIKLGQLLFENFVISKYKTSYPSGQIISININYFIIRLAKPYLATGGATIHNNYGEFIKEGDTLITLIYERLKSGDIIQGLPKVEQLLEARPINSVSINLENGFEDWNNDMIKFIGNLWGFFLSTKISMEQGQINLVDQIQKVYQSQGVQISNKHIEIIVRQMTSKVITLEDGMTNVFLPGELIEFSRTQKMNRALEEAVPYKPILLGITKASLNTQSFISEASFQETTRVLAKAALKGRIDWLKGLKENVILGGLVPAGTGSQEVIWQITLEKKKEIYLKKKKEFFTKKINNVFLYQDTFSIFPTTEIIHNVLKESISQNNKNNFSI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDUB9_BOVIN
Sequence: MAFLSSGAYLTHQQKVLRLYKRALRHLESWCIHRDKYRYFACLLRARFDEHKNEKDMVKATQLLREAEEEFWHGQHPQPYIFPESPGGTSYERYECYKVPEWCLDDWHPSEKAMYPDYFAKREQWKKLRRESWEREVKQLQEETPVGGPRTEALPPARKQGDLPPLWWHIVTRPRERPM
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9, Complex I-B22, CI-B22, NADH-ubiquinone oxidoreductase B22 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TRPB_CAUVC
Sequence: MNAPAKPNDYSAYPDAEGRFGGFGGRYVAETLMPLVLDLGKAYADAKADPEFQAQLKSYNTHYAGRPSPLYFAERLTEHFGGAKIYFKRDELNHTGSHKINNALGQILLAMRMGKTRIIAETGAGQHGVATATVCARFGLPCVVYMGATDVERQKPNVFRMNLLGAEVRPVSSGTGTLKDAMNEAMRDWVTNVHDTYYLIGTAAGPHPYPVMVRDFQSVIGAEAREQILEMEGRLPDAVVACIGGGSNAIGLFHPFLGDEGVRLIGVEAAGHGVSTDKHAASLTGGRPGVLHGNRTYLLQDDDGQIIDAHSISAGLDYPGIGPEHSFLHDIGRAEYVSTTDTEALEAFKLCSTLEGIIPALEPAHALARVGEIAQELGKGKIVVMNLCGRGDKDIFTVAEALGRKI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ILVC_PROMH
Sequence: MANYFNTLNLRQQLSQLGKCRFMSRDEFADEANYLKGKKVVIVGCGAQGLNQGLNMRDSGLDIAYALRQEAIDEKRASWRRATENGFEVGTYEALIPQADLVVNLTPDKQHSAVVQAVQPLMKSGAALGYSHGFNIVEVGEKIRDDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDAKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCYDKMVAEGVEPGYAGKLIQFGWETITEALKQGGITLMMDRLSNPAKMRAYALSEQLKEIMAPLFAKHMDDIISGKFSETMMADWANDDKNLLTWREETGASAFENYPEYEGKISEQEYFDHGVLMVAMVKAGVELAFDTMIEAGIIAESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSFAAVPMLKEFMTTLQSGDLAKHVPDSGTDNAQLRDINEAIRQHPIEIVGKKLRGYMTDMKKIAVAN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RSMG_BACCN
Sequence: MNIEQFQSMLGERGISLSPRQLEQFEMYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSNPLSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEHVRESYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYAVEVLGGQLEEVSTFQLPFEESERNILLIKKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_PORG3
Sequence: MLYYLFDYLEKLQLPGARLFHYVSFRSAVAIILALLLATVIGNRIIERLRKAQIGETIRDLGLEGQLSKKGTPTMGGLIIIISILIPTLLLARLDNVYILLMIVTTLLLGSLGFLDDYIKVFRKKKEGLHGRYKIIGQVGLGFIIGIVLYMNPAVVIKENSEVLRDGQVERVHFNKQEVKSTKTTIPFVKNNNFDYADILPFEGKTKVLFGWILFVCVAVVVVTFISNCANLTDGLDGLATGSSAIIGVVLAIFAYVSSHIEMASYLNIMFIPGAEELTIFAFAFVGATIGFLWYNAYPAQVFMGDTGSLTLGGIIAVFALIIRKEMLLPILCFVFIIEGLSVMIQVFYFKLTKRRTGEGRRIFKMTPLHHHFQKPGNAGIDAWLQKPMQAIPESKITVRFWLVGIIMAAITIATLKMR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEL_SACCA
Sequence: MFLLYLFTSFAAVSGVLGSSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLDTADRISEIGLKDLGYTYVILDDCWSSGRTANGTLVADKEKFPNGMSHVADHLHNNNFLFGMYSSAGEYTCAGYPGSLGHEEEDAEFFASNGVDYLKYDNCYNKGQFGAPETSYKRYKAMSDALNKTGRPIFYSLCNWGQDLTHYWGSDIANSWRMSGDIYPQFTRPDSRCPCDGDQFDCAYAGFHCSIMNILNKAAPMGQNAGIGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLVIGADVNHLKASSYSIYSQASVIAINQDPKGVPATRVWRHQVPQTDKYGQGEIQFWSGPLDNGDQVIALLNGGIKPRPMNTNLEEIFFDSYLGFEQLSSNWDIYDLWANRVDNATSANILNNNSVGNATIYNATALSYKDGMAKNDTRLFGTKIGSISPDGLLNTTVPAHGIAFYRLRRST
What are the official names of this protein?
Alpha-galactosidase, Alpha-D-galactoside galactohydrolase, MELx, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_DESRM
Sequence: MAVKNYKPTSPGRRFVTFSDFSEITKVEPEKSLLEPIKKTGGRNAQGRLTVRHQGGGHKRMFRIIDFKRNKDGIPAKVASIEYDPNRSARIALLNYADGEKRYILAPVGLEVGVIVESGPDADIKVGNCLPLRNIPVGTMVHNIELYPGAGAQMVRSAGAAAQLMAKEGKYANLRLPSGEMRLVLQECRATIGQVGNLEHENVTIGKAGRSRHLGIRPTVRGKVMNPVDHPHGGGEGRNPIGRNPSTPWGKLAMGVKTRGNKKSDRLIVKRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TRUA_SALPA
Sequence: MSGQQSSPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPINVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLAKGVTHYYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLLEVGAHNQPESWIAELLAARDRTLAAATAKAEGLYLVAVDYPDRFDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YQGF_RHOJR
Sequence: MDHAEQGPDRPGVDDPGRGRRIGIDVGSVRIGVASSDPDGILATPVETVPRSKERGPDAPDIRRIADIVEEYEAVEVIVGLPQTLRGERGKAASIATVFAKRLRRKVDPIPVRMADERLTTVTAARALRESGVSARGQRPVIDQAAAVAILQGWLDERSRSVNAGDSGGDAQLPEGGQ
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_TSWV3
Sequence: MSKVKLTRENIISLLTQAGEIEFEEDQIKATFNFEDFCGENLDSIKKMSITSCLTFLKNRQSIMKVVNLCDFTFGKITIKKNSGRVGANDMTFRRLDSMIRVKLIEETGKAENLAIIKSKIASHPLVQAYGLPLTDAKSVRLAIMLGGSIPLIASVDSFEMISIILAIYQDAKYKDLGIEPSKYNTKEALGKVCTVLKSKGFTMDEEQVQKGKEYATILSSCNPNAKGSIAMEHYSEHLDKFYAMFGVRKEAKISGVA
What is the function of this protein?
Encapsidates the RNA.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the tospovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TM114_MOUSE
Sequence: MRVRLGALAGAAALSGALSFVLLAAAIGTDFWYIIDTERLERSSQRMRDQGPANRSQQEPLSSHSGLWRTCRVQSSCTPLMNPFWQENVTVSDSSRQLLTMHGTFVILLPLSLIVMVFGGMTGFLSFLLRAHLLLLLTGILFLFGAMVTLTGISIYIAYSAVAFREAVCLLEERALLDQVDIRFGWSLALGWISFVSELLTGVVFLAAARALSLSQRQDQAI
What are the official names of this protein?
Transmembrane protein 114, Claudin-26.
Protein: GPX5_CANLF
Sequence: MTAWLGASYVLPILLVSFVQTNAKPEKTKMDCYKDVKGTIYEYEALTLNGNERIQFKQYPRKHVLFVNVATYCGLTAQYPELNSLQEELKPLGLVVLGFPCNQFGKQGPGENSEILPGLKYVRPGRGYVPNFQLFEKGDVNGEKEQKVFTFLKLSCPHPSEVLGSFRHISWDPVKVHDIRWNFEKFLVGPDGVPVLRWFHRTPISTVKEDILVYLKQLKMK
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.  May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
What are the official names of this protein?
Epididymal secretory glutathione peroxidase, Epididymis-specific glutathione peroxidase-like protein, EGLP, Glutathione peroxidase 5, GPx-5, GSHPx-5.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPN6_YEAST
Sequence: MSLPGSKLEEARRLVNEKQYNEAEQVYLSLLDKDSSQSSAAAGASVDDKRRNEQETSILELGQLYVTMGAKDKLREFIPHSTEYMMQFAKSKTVKVLKTLIEKFEQVPDSLDDQIFVCEKSIEFAKREKRVFLKHSLSIKLATLHYQKKQYKDSLALINDLLREFKKLDDKPSLVDVHLLESKVYHKLRNLAKSKASLTAARTAANSIYCPTQTVAELDLMSGILHCEDKDYKTAFSYFFESFESYHNLTTHNSYEKACQVLKYMLLSKIMLNLIDDVKNILNAKYTKETYQSRGIDAMKAVAEAYNNRSLLDFNTALKQYEKELMGDELTRSHFNALYDTLLESNLCKIIEPFECVEISHISKIIGLDTQQVEGKLSQMILDKIFYGVLDQGNGWLYVYETPNQDATYDSALELVGQLNKVVDQLFEKASVLY
What is the function of this protein?
Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  In the complex, RPN6 is required for proteasome assembly.
What are the official names of this protein?
26S proteasome regulatory subunit RPN6, Proteasome non-ATPase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
Protein: Y1186_LACLM
Sequence: MNLILAILLMVVCLLAGFFLGTWFSQRQTKKLLMDNPPLNEDAVRLMMGSMGRKPSEVQVQQVLRQIRAAAKQSDTNKK
What are the official names of this protein?
UPF0154 protein llmg_1186.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRHO_NITHX
Sequence: MLKVAALYQFAPLPDFREVREPLRALCVGLSVKGTILLAGEGINGTVAGMPDAIDALAAELQTGTLFSGRLDNLELKFSQASVMPFARLKVRLKKEIVTLGDPATDPTRAVGIYVEPKDWNGLIAAPDTLLIDTRNAFEVAMGTFEGAVDPQLARFGEFKDFVAQKLDPDRHRRIAMFCTGGIRCEKASSYLLSRGFKEVYHLKGGILKYLEGIPESESCWRGECFVFDDRIALGHGLTESRRAGRLMDGAPGDD
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CYB_BRANA
Sequence: MTIRNQRFSLLKQPISSTLNQHLVDYPTPSNLSYWWGFGPLAGICLVIQIVTGVFLAMHYTPHVDLAFNSVEHIMRDVEGGWLLRYMHA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISPF_SALTI
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PGM48_ARATH
Sequence: MAVSVSAPVLSLCYNQSGELSRSLGYRLPKKVGFSSGRRSVSYIGFGAEKVGRFRVRVPICRAVPPLLFKDLDADDFRHPFDKQNTLLLRAIPGLNEFGKALLGSMTEQIMLLENIGTSVLVSKNQLSDLHGLLVEAAEILNIEAPDLYVRQSPVPNAYTLAISGKKPFIVVHTSLIELLTSAELQAVLAHELGHLKCDHGVWLTFANILTLGAYTVPAFGQMIARTLEEQLLRWLRSAELTCDRAALLVAQDPKVVVSVLMKLAGGCPSIADQLNVDAFLEQARSYDKASSSPLGWYIRNAQTSQLSHPLPVLRAREIDEWSRSLEYKSLLKRANRKSTVQKV
What is the function of this protein?
Metalloendopeptidase with a Zn-dependent proteolytic activity and substrate cleavage upstream of hydrophobic residues (PubMed:27895226).  Positive regulator of senescence, probably by degrading CCD4, thus participating in the controlled removal of carotenoids from the thylakoid membrane during the senescence process (PubMed:27895226, PubMed:28534654).
What are the official names of this protein?
Plastoglobule-localized metallopeptidase 48, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family. M48D subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule. Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: CC183_MOUSE
Sequence: MKVHNEAAVEAQITELRTITRLQEQCRALQIQGVKEKTAQNKATMGILRSNLRRGAQDWALAKKHDQWTISKACGKDTSMRLAHGRSTLEVAREKLRKYVFDRVNTHNILIHLVRRRGQKLESLQLELASLRNQPDATKDELRQLQIIRQLENNIEKTVIKITTSQNIHTLYKVLLDYLKKVLAEYPTELDKLQNLVANYCSELSDMTVMSQDAMMITDEVKRNMRQGEATFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGRRDLDFPSNLMTMENVKVKKRKTSVADIQYQTKVTTLVERVKSAVQCSHLWDIAGRFLAQKNTEENLELQMEDCEERRTQLEALMKKLELEEAVLKFHQTPSAVGFNSIQKKMKNMLEEEEARLKQAQNNMNKGQQLLLVIQTGIDNLYIRLIGITLPTFQKEIAVSNTLDVYGKLDYCEGKLIYLAERMQTLSRNEEVDTKVRDTLESSTLKEKHNTRITFEDPEEDMIETFQFADVDHSYVPSRAEIKKQAQQLIEAKLKGAKKKKK
What are the official names of this protein?
Coiled-coil domain-containing protein 183.
Protein: UROM_RAT
Sequence: MGQLLSLTWLLLVMVVTPWFTVAGANDSPEARRCSECHDNATCVLDGVVTTCSCQAGFTGDGLVCEDIDECATPWTHNCSNSICMNTLGSYECSCQDGFRLTPGLGCIDVNECTEQGLSNCHSLATCVNTEGSYSCVCPKGYRGDGWYCECSPGFCEPGLDCLPQGPSGKLVCQDPCNVYETLTEYWRSTDYGAGYSCDSDMHGWYRFTGQGGVRMAETCVPVLRCNTAAPMWLNGSHPSSREGIVSRTACAHWSDHCCLWSTEIQVKACPGGFYVYNLTEPPECNLAYCTDPSSVEGTCEECGVDEDCVSDNGRWRCQCKQDFNVTDVSLLEHRLECEANEIKISLSKCQLQSLGFMKVFMYLNDRQCSGFSERGERDWMSIVTPARDGPCGTVLRRNETHATYSNTLYLASEIIIRDINIRINFECSYPLDMKVSLKTSLQPMVSALNISLGGTGKFTVQMALFQNPTYTQPYQGPSVMLSTEAFLYVGTMLDGGDLSRFVLLMTNCYATPSSNSTDPVKYFIIQDRCPHTEDTTIQVTENGESSQARFSIQMFRFAGNSDLVYLHCEVYLCDTMSEQCKPTCSGTRYRSGNFIDQTRVLNLGPITRQGVQASVSKAASSNLGFLSIWLLLFLSATLTLMVH
What is the function of this protein?
In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.  Protects against urinary tract infections by binding to type 1 fimbriated E. coli.  Binds to bacterial adhesin fimH which mediates the stable formation of bacterial aggregates, prevents the binding of E. coli to uroplakins UPK1A and UPK1B which act as urothelial receptors for type I fimbriae, and allows for pathogen clearance through micturation.  Also promotes aggregation of other bacteria including K. pneumoniae, P. aeruginosa and S. mitis and so may also protect against other uropathogens.
What are the official names of this protein?
Uromodulin, Tamm-Horsfall urinary glycoprotein, THP.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell projection, cilium membrane. Note=Only a small fraction sorts to the basolateral pole of tubular epithelial cells compared to apical localization. Secreted into urine after cleavage. Colocalizes with NPHP1 and KIF3A. SUBCELLULAR LOCATION: [Uromodulin, secreted form]: Secreted. Note=Detected in urine.
Protein: COL10_CAEEL
Sequence: MEKFLVTLSTGAASIAVLAVLFTVPSLYNTINEVHDEVLDGVSVFRVETDSAWTEMMDIQITVTPPTKPRVNPFNSIFRQKRQTFSGLPAWCQCEPTKPTCPPGPPGPPGQPGAPGTPGAPGPKGDDNTATFAPLTCAPVSQDCVKCPEGPAGPAGPEGPAGPAGPDGQPGAPGNAGNPGSDGQPGAPGDNGQDGAPGQDGQPGAPGQDGQRGSGAPGGPGAPGNAGPAGPAGQDGAPGQDGQPGPAGPAGQDGAPGNAGSDGQPGAPGGPGLPGNDAAYCACPPRSAVFVSRH
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
What are the official names of this protein?
Cuticle collagen 10.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: IF2P_METM5
Sequence: MALRCPIVSVLGHVDHGKTSLLDKIRRTRVTQREAGGITQHIGASEIPINTIKKVSKDLLGLFKADLSIPGILVIDTPGHEAFTSLRKRGGALADIAILVVDINEGFKPQTIEAINILKQCKTPFIVAANKVDRIPGWNSSEGPFILNFNEKNQHPNAMTEFEIRLYENIIKHLNELGFDADLFSRVKDTTKTINVVPVSAMTGEGVPDLLVIISGLAQKFLEQKLALNVEGYAKGTVLELKEEKGLGKTIDAIIYDGIAKTGDFLVVGNPDGVIVSKIKALLKPKELDEMRDPKDKFKPSKQISAATGVKISAPDLDSVIAGSPLRIVPKNQVDAAKEEVLQEVEEFTILTDDEGIIIKADTMGSLEALANELRKVNAKIKKAEVGDISKKDVIEASSYASSNPLNGLIISFNTKVLADAKAEIEKSDVKLLEGKIIYKLVEEYEEWTKEMEELMKSDEINRLTKPAMIKILPNCIFRQKEPAVCGVEVLYGTLKIGSPIMSEDGKKLGYVKEMRDSQQENIKEAKVGMQVPVSIDGNIVLGRNAKENDILYVEVPEPEARKLHHEFKDELRGDEKEALSRYMELKQKIENNIFWGM
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: SYM_PSEPK
Sequence: MSEPRQILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKLRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSSDFADFLVDFDNFHSTHSDENRELSSLIYSRLREAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCAAEDQYGDNCEKCGATYAPTELKNPKSAISGATPVLRDSQHFFFKLPDFQAMLQQWTRSGTLQDAVANKLAEWLDSGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWHEGSKAELYHFIGKDIVNFHALFWPAMLEGAGFRKPTAVNVHGYLTVNGAKMSKSRGTFIKARTYLDHLQPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNEGVMVGGDAAPELTEAFLAAAPSIAEAYEARDFGRAMREIMALADRANAWIADKAPWSLAKQEGKQDEVQAICAQGINLFRQLVIFLKPVLPVLAADAEAFLNVAPLTWNDHLTRLENHQLNPFKALMSRIEPAKVEAMVAASKEDLLAAEAKAPAGNGELAKDPLSAEIEFDTFAAVDLRVALIVKAEAVAGADKLLQLTLDIGDERRNVFSGIKSAYPDPSKLEGRLTMMVANLKPRKMRFGVSEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_LEGPH
Sequence: MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YCX4_CHLVU
Sequence: MRAKSIAYVWSTATQSLTPEQCEAMIKLREPLNVVFDQGMRNVQLILKKQDHFDELMTTYETCQTAEKNFHETTFLPAKANLDTFVGSQKARKEAANHFKKIKSQSIEYTKEANQAFTAAMKYDQNHIVPAKNALQKIETCIINEVEDKLEEILNPSSITEKTLKGKTQRQKTNAALINRIKRRNTAFNNHDNNIINSFHGPSSFEQISIYYNLPIDRSFQKMVQKQLEKIKVLPN
What are the official names of this protein?
Uncharacterized 27.2 kDa protein in rrn23-psbC intergenic region, ORF236.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COAD_BRUSU
Sequence: MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVLHKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKFKS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.