PharMolix/UniProtQA huggingface dataset:
Protein: EX7S_TRIL1
Sequence: MAAEKFETSLKKLEEVVRKLEGGSLSLDDSIKAFEEGVKHAAFCAKKLDEAERKVEVLIKQRDGSFRKEPFTTDNDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_CROS8
Sequence: MSTENKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLVFVVSFKYLTFVMRADNAGEGGILTLMSLAGRNTSARMTSVLVILGLIGGSFFYGEVVITPAISVMSAIEGLEIAAPSLDPYIVPLSIVVLTLLFMIQKHGTGMVGKLFAPIMLAWFLVLAVLGARSILNNPEVLQALNPVWAVHFFLEYKAVSFAALGAVVLSITGVEALYADMGHFGKLPIRVAWFSVVLPSLVLNYFGQGALLLKTPEAIKNPFFLLAPDWALIPMLILATLATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPVVNWLLYFAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILFATAARKNWHWSRILVGLMVVAFLCVDVPLFSANLEKLFSGGWLPLSLGLVMFIIMTTWKSERFRLLRRMHEHGNSLDAMITSLEKSPPVRVPGTAVYMSRALNVIPFALLHNLKHNKVLHERVILLTLRTEDAPYVHNVKRVTLEQLSPTFWRVVASYGWRETPNVEEIFHRCGLEGLSCRMMETSFFMSHESLIIGDKRPWYLRLRGKLFLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACCD_CLOBJ
Sequence: MLKNLFRKTKYITVSQKNIGNYKRENTPTIPDGMWVKCNKCGEILYQNDLEKNYMVCNLCGNHFRIGVKERIKYLFDKDTFKEWDYKIKTENPLDFKGYDEKIEHIKEKTNLSEAVTTGKGKIAGMEVVVCIMDSKFMMGSMGSVVGEKITRAIERAIELRLPVIIFTASGGARMQEGILSLMQMAKVSSALAKLDEEGLLYICVLTDPTTGGVTASFAMLGDIILAEPDALIGFAGKRVIEQTINEKLPEDFQKSEFLLEHGFIDKIVPRSDLRKVLAKLINMHQNSF
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPPB_ECO57
Sequence: MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHWLPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIRY
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUSK_RAT
Sequence: MRELVNIPLLQMLTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSALRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKLVKLEVEVFARILRAPESHNVTFGSFVTLRCTAIGMPVPTISWIENGNAVSSGSIQENVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATVSIAEWSKSQKESKGYCAQYRGEVCDAVLVKDSLVFFNTSYPDPEEAQELLIHTAWNELKAVSPLCRPAAEALLCNHLFQECSPGVLPTPMPICREYCLAVKELFCAKEWLAMEGKTHRGLYRSGMHFLPVPECSKLPSMHQDPTACTRLPYLDYKKENITTFPSITSSKPSVDIPNLPASTSSFAVSPAYSMTVIISIMSCFAVFALLTITTLYCCRRRREWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTVGV
What is the function of this protein?
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:23326516).  Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex.  The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane.  May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK.  DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering.  May positively regulate Rho family GTPases through FNTA.  Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression.  Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK.  May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation.
What are the official names of this protein?
Muscle, skeletal receptor tyrosine protein kinase, Muscle-specific tyrosine protein kinase receptor, MuSK, Muscle-specific kinase receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Single-pass type I membrane protein. Note=Localizes to the postsynaptic cell membrane of the neuromuscular junction.
Protein: IF1_BARBK
Sequence: MSKEEVLEFSGVVIELLPNAMFRVKLENDHEIIAHTAGRMRKNRIRVLAGDKIMVEMTPYDLTKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_PSEA8
Sequence: MPSRNILVINCGSSSIKFALVNEAHSLFPLHGLAERLGSRDAVLRWKRGGDSDSLMIPNADHRAALAQLLPMVQNAAGGKLHGIGHRVVHGGELFTHATRIDDRVVEAIRATAPLAPLHNPANLQGIEAAMTLFPKLPHVAVFDTAFHQSLPEHAYRYALPEALYREHGVRRYGFHGTSHRYVSHRAAEMAGLAVGDSSWLSAHLGNGSSTCAIVNGQSLDTSMGLTPLEGLVMGTRSGDVDPNLHSHLARTLGWSLERIDSMLNNESGLLGLSDLSNDMRTLEQEREQGHPGAALAIEVFCYRLAKSLAAMSCALPQLDGVIFTGGIGENSPLVRAKTAAHLRLFDLRLDQEANARCVRGVAGPIQAAGHPRVLVIPTNEERQIALDTLALLD
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CALS8
Sequence: MPNKVHVKKGDTVVVISGKYKGKQGKVLTVLPKDKKVVVEGVNIVKKHVRPNPKMPQGGIITQEAPIWACKVMLVCPKCNKPTRIGHRFIQEGEEEKKVRTCKKCGEIID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: COAD_HELPY
Sequence: MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATKSFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_NITOC
Sequence: MKENVLDVLMYLFQNYMDSEVESQPTKESLEVELTEAGFHHAEIGKAFDWLEGLALLQQSEPRRFPVTNSSIRIFTLHEKEKLDTECRGFLLFLEQVGVLDSMTRELIIDRVMALEAEDFDLEHLKWVILMVLSHQPGQEAAYAWMEDLVFDEVSDLLH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RL29_BDEBA
Sequence: MKFVEIKDLSVAELKKKRAALSEELFQARIKNSIGQLSNPVQIRGLRRDIAKINTAIVKKVAR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL27_CITK8
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGETVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPNNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: APRL6_ARATH
Sequence: MEKKLTLLLLVVVVLFVNLTNATVRVQICPRESAKDYILGFRDKSALHRPGFVTEGDDRWLQMAADMVDKKNKCDYAALLFYASWCPFSRLVRPSFDLMSLLYSSVPHFAIEESSVKASTLSKYGVHGFPTIILMNSTMLVVYRGSRTLDSLVAFYTDVTGIETMDERWVERNRLVPHFHAEPENCPFPWARRSPENLLRQETYLTLATVFVLLRLLHLISPTMVVFVKFTWGRVSNMRLGNPLEHTVTMYLKEPCMSSNLQEGAMNARAWASKSLATVSIAESSSSSRSVSASQ
What are the official names of this protein?
5'-adenylylsulfate reductase-like 6, Adenosine 5'-phosphosulfate reductase-like 6, APR-like 6, AtAPRL6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PRGR_PITIR
Sequence: MTELKAKGPRAPHVAGSPSSPKVGSPLPCSQAAGPFPGSQTSDTLPEASALPISLDGLLFPRICQGQDPTDEKTQDQQSLSDVZGAYSRVEATRGAGGSSSRPPEKDSGLLDSVLDTLWEPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGGKAGDSSGMAAAHKVLPRGLSPSRQLLLPTSGSPHWSGAPVKPSPQPAAVEVEEEDGSESEDSAGPLLKGKPRALGGAAAGGGVAAVPPGAAAGGLSLVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVTDFIHVPILPLSHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPSASSTPVPGGDFPDCAYAPEAEPKDDAYPLYGDFQPPALKIKEEEEGAEASARSPRSYLVAGASPAAFPDFPLGPPPSLPPRAPPPRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPSQQGQFAPPPCKAPGAGGCLLPRDSLPSTSASAAATAAGAAPGLYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNENQALSQRFTFSPSQDIQLIPPLINLLLSIEPDVIFAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: DTDA_IGNH4
Sequence: MKVTVVYYPGDPAAKGAAEALEREYGIKALELPEDPPFFDFNSLAGDAFIVLSRHSSEKRVKAFTVHHTGNFGEAKLGGEPKRLGVAYPSLACSLLRAMNAFRREGYDVTYEATHHGPTSDKPLVFAEIGSVKEDWEDPANHEVLAKAVASWEEHRCEAPKAVWVGGPHYSKRATKRCLEGEACFGHIAPKYALDHLDEDLLRQMVERSFERPERAYVEKKSLKSELRLRVVKALEDLGLEVLVV
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: ATPD_STRPJ
Sequence: MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTGLPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLEKETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHKTIDVSIKQQLKVVKENLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYH_NITEU
Sequence: MPEPIRAVRGMNDILPDESGLWAFFEDTIRTWLAAYGYRNLRTPIVEQTDLFVRSIGEVTDIVEKEMYTFVDHLNGENLTLRPEGTASCVRAVIEHNLLYAGPQRLYYSGPMFRHERPQKGRYRQFHQVGVEALGFAGPDIDAELIVMCARLWRLLGISDVRLEISTLGSTESRSVYRARLISYLEKFCDDLDEDARRRLKTNPLRILDSKNPAMREILAGAPRLFDDLDEDSLAHFEALQRILRNQDISFEINNRLVRGLDYYNRTVFEWVTDKLGAQGTICAGGRYDGLIAQIGGKPAPACGFAMGIERILALMGENGAVGAHAIPDIYVVHQGEAAAEFSWKVAESLRDDGLKVVLHSGGGNFKAQMKKADASGARFAAIIGEDEVVAGQISIKPLREAAEQIRVDLAGAAALLGNI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_ECOBW
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PTUB_BACMK
Sequence: MIKVQREAEPAVLNLTDSDSIGFKELEAAKKTTFTKDTKFPFEAYKDESVKNLLKKMFNGKCGYCESIINVTSYEEIEHFRPKKAINIEGIQGLTYPGYYWLAMSWNNLLISCQRCNRSHKKNYFPIENESNRAKAPGEESGEEVLLLNPCEDDPSEHLEFKDTGIIEFKEGSKKGEKSIKVYALHRRELTEERAKVAKDIELKKVQILDGLSTLKVLLRYQEDSDLQKEIEKTVSNIISLYDFIFEYENDPNRPYQAMVTQITSDFLSERKELINKLKTTSNRKNSCEQSHISS
What is the function of this protein?
Component of antiviral defense system Septu type II, composed of PtuA and PtuB.  Expression of Septu type II in B. subtilis (strain BEST7003) confers resistance to phages SBSphiC and SpBeta (PubMed:29371424).  May be a nuclease (Probable).
What are the official names of this protein?
Septu protein PtuB, Putative nuclease PtuB.
Protein: RFPLA_RAT
Sequence: MAHFFKENSSCYFCFRYLENPVYLNCGYICCFQCLDSLEKSPEGDGVLCPNCSVVSLKEDIRHAKQLRNLVTTVKDLEPQLNFILTMDPSMKIFQVNMILDVDTAQNNLIISEDLRSVYHTSQTQDRKKCAERFDPSPCVLGSSRFTSGCHYWEVVVGTSKEWDIGICKESINRQEVVYLSEKKGFWTVGVRNEEVYAASTDPLTVLLVNPRLHRVGIFLDLLEKSVSFWDLGDGSHIYTFLEIPDTEPFRPFFSPANTYPDEEQVISICPVMNPSIFGLPVNPV
What are the official names of this protein?
Ret finger protein-like 4A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NAPA_PSEAE
Sequence: MNSPRPTPPPFAAAAAGLPILVRASNLVTEADVTSLVWNKAPCRFCGTGCSVMVATRDGQVVATHGDIKAEVNRGINCVKGYFLSKIMYGSDRLTRPLLRMKDGKFDKQGEFQPISWEQAFDIMAEKFKAALKAKGPESVGMFGSGQWTVWEGYAANKLFKAGLRSNNIDPNARHCMASAVMGFMRSFGMDEPMGCYDDIEATDSFVLWGSNMAEMHPVLWSRVTDRRLSAPQVKVAVLSTFEHRSFELADLPMVFKPQTDLIILNYIANHIIESGAVNRDFVERHVRFAHGAEDIGYGLRPDDPLEKKAKNADKANTWSDIDFKAFAEFVKPYTLERTARESGVPAERLKALAELYADPKRKVVSFWTMGFNQHTRGVWANNLIYNIHLLTGKISEPGNSPFSLTGQPSACGTAREVGTFSHRLPADLVVTNPKHRETAEKIWKVPAGTIQEKVGFHAVQQSRMLKDGVLNVYWTQVSNNMQAGPNVMQEVLPGWRNPDNFVIVSDVYPTVSAQAADLILPSAMWVEKEGAFGNAERRTQFWHQLVKAPGEAKSDLWQLVEFSKRFTTDEVWPAELLAKAPELKGKTLYDVLFRNGQVDRFPASDLAKGYANDEVDAFGFYIQKGLFEEYAAFGRGHGHDLAPFDAYHEARGLRWPVVDGKETRWRYREGYDPYVSKGSGVQFYGYPDKKAIVFALPYEPPAEAPDQDYPFWLATGRVLEHWHTGSMTARVPELYKAVPDALVYMHPEDARQLKLRRGSEVKVVSRRGEIRARVETRGRNKPPQGLVFVPFFDANKLINKVTLDATDPISKQTDYKKCAVRIELLNLA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RTCB_PYRAB
Sequence: MTVPLKRIDKIRWEIPKFDKRMRVPGRVYADDVLLEKMKSDRTLEQAANVAMLPGIYKYSIVMPDGHQGYGFPIGGVAAFDVNEGVISPGGIGYDINCLAPGSKVLTEHGYWLKVEELPEKFKLQGVKVYNLDEGHNDTSNVAFVAEREVETGEMAVRVTTESGRIIEGSEDHPVLTPEGYVYLGNLKEGNLVIVYPFEGVEYEERKGVILDEDAFKDEDPQVLSFLREKGLVPLRWDDPRIGTIARILGFAFGDGYLGEMGGRLTLTFYGKEETLRELKKDLERLGISANLYVRESIETTSGHSEGKSLSIELRVTSRSFALFLEKLGMPRGKKTEKAYRVPGWILEAPLWVKRNFLAGLFAADGSIVEFKGNTPLPINLTQSKSDELAENLVEFLGDVAKLLAEFGIETTLYEVKSKKGVTYRLSIVGEDSIRTFVERINYEYDPEKKVKGLIAAAYLKLKERIVKEAHEAVKDDFPTFEEFAKERGYEGGFVAEKVVKVERVKPEYTKFYDIGVYHEAHNFIANGIVVHNCGVRLIRTNLTEKDVRPRIKQLVDTLFKNVPSGVGSQGRVRLHWTQIDDVLVDGAKWAVDNGYGWEEDLERLEEGGRMEGADPDAVSQRAKQRGAPQLGSLGSGNHFLEVQVVDKIFDPEVAKVYGLFEGQVVVMVHTGSRGLGHQVASDYLRIMERAIRKYRIPWPDRELVSVPFQSEEGQRYFSAMKAAANFAWANRQMITHWVRESFQEVFRQDPEDLGMSIVYDVAHNIGKVEEHEVDGKKVKVIVHRKGATRAFPPGHEAIPKIYRDVGQPVLIPGSMGTASYVLAGTEGAMKETFGSTCHGAGRVLSRKAATRQYRGDRIRQELLNRGIYVRAASMRVVAEEAPGAYKNVDNVVKVVSEAGIAKLVARMRPIGVAKG
What is the function of this protein?
Essential for tRNA splicing and maturation.  Acts by directly joining spliced tRNA halves to mature-sized tRNAs.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: YACG_ACTPJ
Sequence: MSETIVNCPTCNQDVIWKPESKYRPFCSERCQLIDLGEWANEEKRIAAVENDVMTSDLEGHY
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: LRPB_BACSU
Sequence: MQIDSIDFQILQLLNKNARIQWKEIGEKIHMTGQAVGNRIKKMEDNGIIKAYSIVVDELKMGFSFTAFVFFFMNAYMHDDLLKFIATRNEISEAHRVSGDACYLLKVTVHSQEVLNHLLNDLLKYGNYQLYLSIKEVKKHYNTSLMSDE
What is the function of this protein?
Negative regulation of glyA transcription and kinB-dependent sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator LrpB.
Protein: NUON1_THEYD
Sequence: MNISQIPLQVEALIPEITLTGFASLILLAGLLKLKNEVLVWSSVLFLVIFAFFIPSFEGEAFNGMFLNDFLTIYLKLIIIIGTIISLLVLTSYLKEKLIRFNESIAFILFSALGMMLLVSARELISFFLSFELMSLSIYVLVGIRRYDVKSNEAAVKYFMLGGFSSAIMLFGIAFIYGATNTTELSLILKVISNYNPLILIGLGLFIVGLCFKIALVPFHMWAPDVYEGAPTPVTAFISTLPKVAILGAFGRVLVEIFRDYYIDWSNFLIVLSIATMATGNFFALIQKNIKRMLAYSSIAHAGYIIIGVIVGTQSGFNSVVAYMFIYTLMNIGAFAMVIAFNEESIENYKGLHKFHPALAIAMLIFMFSLTGVPPTAGFIVKFNIFLQAVKAGFTWLVVIAVIFTVISAYYYLRIVMYMYMKEPVKLPEPIYSRELEVAILICTIGVTFLGILPLFLI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_STRP1
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: T55BA_DANRE
Sequence: MADGERSPLLSDLGDGALGSGNGGVSPGAASLGAPNKPQSFPPFPSSTQPPVLLSENPPPYSPLTSPESGSAPVISCRVCQSLISVEGKIHQHVVKCGVCNEATPIKNAPAGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPASPDPQPAGARVSCGHCSNTFLWTEFTDRTLARCPHCRKVSSIGQRYPRRRSLWCYLLCLLFSISAAGLIAGTWSQAQVYGGIYASWAAALLLVVLTLARALYWSCMRVSQPLHNLT
What is the function of this protein?
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate.
What are the official names of this protein?
Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-A, PtdIns-4,5-P2 4-Ptase I-A, Transmembrane protein 55B-A.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.