PharMolix/UniProtQA huggingface dataset:
Protein: PA23_CROAT
Sequence: NLLQFNKMIKIMTKKNAFPFYTSYGCYCGWGGRCCFVHDCCYEKTDIYSYSWKRQICECDR
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that displays edema-inducing activities.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_AGRRK
Sequence: MAEQTTKDDKPLFGRPWIFIRGVPAMKFLPPEGPLEVAFAGRSNVGKSSLINALVGHKGLARTSNTPGRTQELNYFVPDGFSGEGGDLPPMALVDMPGYGYAEAPKEQVDAWTKLVFDYLRGRTTLKRVYVLIDSRHGIKKNDEEVLALLDKAAVSYQIVLTKTDKIKEAGLPKLLADTAEKIRKRPAAYPGILSTSSEKGDGLEEVRQAIRLTVGIPF
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: 3001L_ASFWA
Sequence: MVSLTTCCLKNIVNQHAHVENTVLLYHLGLRWNCKTLYQCTQCNGINYTNSHSDQCKNKDLFLMKVIVKKNLAVARTLLSWGASPEYARLFCRNTEEEQALNVQHVADMSSSKILERLTMSYKENDEQLLITFYLLNLSTNFSTNLREQVRFNIVSYIICDLAIHQTFKTFYAKNYSLSTLYCIFLAIYYKLYTALRKMVKIYPGLKPFVYLTGFIFDDETVMETYNSTDDEISECKNRIIAIKGCYGNFHCRSDIDHMYAFSQNDYW
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 300-1L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 300 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: EFTS_PHOPR
Sequence: MATVTAALVKELRERTAAGMMDCKKALVEADGDIELAIDNMRKSGAAKAAKKSGNIAAEGTIIIKEVDGIAAILEVNCQTDFVAKDASFLAFANEVADAALAGRVEVAELQAAFEEKRIALVTKIGENISIRRVEFIEGAQIGSYRHGDRIGVVVVVVASDADQETIKQVAMHVAASKPEFVTPEDVPADVVAKEKQIQIDIAIQSGKPAEIAEKMVVGRMKKFTGEVSLTGQAFIMDPAQTVGQMLKAKGATVTNFIRFEVGEGIEKAKEMSFAEEVAAVQKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_PELTS
Sequence: MRAVVQRVARGSVTVEGSVRGEVERGLVVLLGVGRGDTDDDAGYLADKVANMRIFEDGQGKMNLSVLDVKGSVLAVSQFTLYGDCRKGRRPGFSGAAPPEEARRLFELFVKELEKYGLKVATGVFREHMTVEIINDGPVTLLLDSKKNF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BORPA
Sequence: MKTFVAKPHEVKRDWFVIDAKGKVLGRVASEVAHRLRGKHKPEFTPHVDTGDYIVIINAADIVVTGNKAQDKKYFRHTTYPGGIRETNFEKMQQRFPGRAIQKAVKGMLPKGPLGYAMIKKLKVYAGAEHPHTAQQPKPLEF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y025_BACC4
Sequence: MMRGGMGNMNNMMKQMQKMQKDMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKIKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCB4264_A0025.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PTH_PROMA
Sequence: MSSGNFQLLAGLGNPGSKYTSTRHNVGFMALERLAKKESVQFAMNKKIFGHIANIEIGANKRKLLMPNTYMNESGRSISAAIKWFDLEINQILIFVDDMDLPLGKLRFREGGGSGGHNGLKDIIKHLGSQDFCRLRIGIGPPSINQGDRKQKTIPHVLGKFDQAESKVITKVLDKVIKGLEVIEQYGLVKGTSFLNSSLTATDG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC_SHEEP
Sequence: MPLNVSFANRNYDLDYDSVQPYFYCDEEENFYHQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSSADRLEMVTELLGGDMVNQSFICDPDDETLIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDGGSPSPARGHGGCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKPCASPDSTAFSPSSDSLLSSAESSPRASPEPLALHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQPPAKRSESGSPSAGSHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEKDVLRKRREQLKLKLEQIRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: OBG_CHLPD
Sequence: MKFVDSATISIQAGDGGRGCVSFRREKFVPKGGPDGGDGGRGGHIYLRANKQLATLLDFRYRKQYLATRGAHGQGSRKTGKDGSDIVIEIPCGTLVKNAQTHELIADLTEDGQEMLVARGGKGGRGNQHFATPTRQAPRYAEPGLKGEAFELEMELKLMADVGLVGFPNAGKSTLISVLSAAKPKIADYPFTTLVPNLGIVRYEEYKSFVMADIPGIIEGAAEGKGLGLQFLRHIERTKILVVLVAADAADIALEYQTLVQELEKFDSGLLLKPRIAVITKMDIASEDMVVPELEGVKLLMISSVTGKGLKELKDELWRQVSTCSRSEDQPLDEHLG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBL17_ARATH
Sequence: MGICFSAEDQHYQFSQQQNYPKKTTPGKKAAVYLMKSDCEDVVGKVSGSGSGGGGLPLAPKNIKDLQSNPGYENVDIFTYEEMKIATKQFRPDYILGEGGFGVVYKGVIDESVRVGFKSTKVAIKELNPEGFQGDREWLAEVNYLGQLSHPNLVKLIGYCCEDDHRLLVYEYMAMGSLEKHLFRRVGCTLTWTKRMKIALDAAKGLAFLHGAERSIIYRDLKTANILLDEGYNAKLSDFGLAKDGPRGDQTHVSTRVMGTYGYAAPEYVMTGHLTSRSDVYGFGVLLLEMLLGKRAMDKSRACREHNLVEWARPLLNHNKKLLRIIDPRMDGQYGTKALMKVAGLAYQCLSQNPKGRPLMNHVVEVLETLKDDGDAQEEVMTNLHSRGKSVTLYEASSDSQGTRDGNGQRRRRPESGRSKSEAAVDTEKYVSTLSEPDTTKI
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL17, PBS1-like protein 17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MYSP_TAESO
Sequence: MSESHVKISRTIIRGTSPSTVRLESRVRELEDLLDLERDARVRAERNANEMSIQLDTMAERLDELSGTSSQTHDAIRRKDMEISKLRKDLENANAAFETAEATLRRKHNTMISEISSEVENLQKQKGRAEKDKSQLMLEIDNVLGQLDGALKAKASAESKLEGLDSQLTRLKALTDDLQRQMADANSAKSRLAAENFELVRVNQEYEAQVVTFSKTKAALESQLDDLKRAMDEDARNRLSLQTQLSSLQMDYDNLQARYEEEAEAAGNLRNQVAKFNADMAALKTRLERELMAKTEEFEELKRKLTVRITELEDMAEHERTRANNLEKTKVKLTLEIKDLQAENEALAAENGELTHRAKQAENLANELQRRIDEMTVEINTLNSANSALEADNMRLKGQVGDLTDRIANLDRENRQLGDQLKETKSALRDANRRLTDLEALRSQLEAERDNLASALHDAEEALKEMEAKYVASQNALNHLKSEMEQRLREKDEELENLRKSTTRTIEELTTTISEMEVRFKSDMSRLKKKYEATISELEVQLDVANKANVNLNRENKTLAQRVQELQAALEDERRAREAAESNLQVSERKRIALASEVEEIRSQLELSDRARKNAESELNDANGRISELTLSVNTLTNDKRRLEGDIGVMQGDLDEAVNARKAAEDRADRLNAEVLRLADELRQEQENYKRAETLRKQLEIEIREITVKLEEAEAFATREGRRMVQKLQNRVRELEAELDGEIRRAKEAFANARKYERQFKELQTQSEDDKRMILELQDLLDKTQIKMKAYKRQLEEQEEVSQLTMSKYRKAQQQIEEAEHRADMAERTITIKRTIGGPGSRAVSVVREINSVSRGNRATSIM
What is the function of this protein?
Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.  It is a prominent antigen in human cysticercosis, may have a role as a modulator of the host immune response.  It is able to bind collagen and has complement inhibitor activity.
What are the official names of this protein?
Paramyosin, Antigen B, AgB.
What is the protein family that this protein belongs to?
Belongs to the paramyosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Secreted. Note=Thick filaments of the myofibrils. Can also be secreted.
Protein: RL11_TROWT
Sequence: MADKKVVGVIKLQIQAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQKGNVIPVEISVYEDRSFTFVLKTPPVVELIKKAARISKGSPTPHNLKVAQITPEQVKSIAEAKMVDLNANDIDAASKIVRGTARSMGVTVA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MSHR_GORGO
Sequence: MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVVDTLLLLLEAGALAARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYRSIVTLPRARRAVAAIWVASVLFSTLFIAYYDHTAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHKGFGLKGPVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_SACD2
Sequence: MMDSVQIRKYLPHRYPFLLIDRVVELVEGDYILAYKNITINEEVFQGHFPNYPVFPGVMLIEAMAQACGVLGFKTMDKTPDDGSIYLFAGIDNVRFKRQVIPGDRVFFNCKKISDKRGIWKFECVATVDDQLVTSATIMCADRSI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STRP6
Sequence: MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA5_TRYBB
Sequence: MFSSKTEYDRGVNTFSPEGRIFQIEYAIEAIKLGSTSLGIQTPDAVIIAAEKRVPSTLVDPSSVNKILEIDHHIGTVLSGMVADARILVDHARVEAQNHRFTYDEPMSVESCALATCDLSVQFGESGGRKKLMSRPFGVSLLIAGVDENGPQLWQTDPSGTYTRYDAQAIGGGAEAAQTVFSERYHRNMTVEEAENLTVQILRQVMEEKLTKTSVEIAIVPVSTGRLQIYDQEQIQRIIDRQAEEN
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-5, 20S proteasome subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CPHB_TRIV2
Sequence: MAPKVVDRRNTMPQLQAKSLEMRTPQATKTAVLVIGGAEDKVHGREILRTFFGRAGASKAYITIIPSASREPAIIGGRYIRIFEEMGAEKVEILDIREREQCESSQVRASLEACSGVFLTGGDQLRLCGVLSDTPVMEIIRQRVRGGQLTLAGTSAGAAVMGHHMIAGGGSGETPNRSLVDMATGLGLIPEVIVDQHFHNRNRMGRLISAVAAHPDRLGIGIDEDTCAVFERDGWLQVLGKGSVTIVDPTELTHTNEPHVGANEPLTVHNLRLHILSYGDRFHLYQRTVLPAVHRISS
What is the function of this protein?
Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
What are the official names of this protein?
Cyanophycinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
Protein: TC10B_ARATH
Sequence: MAAIFSLFLFFILFIVSLLIILSFIVRPRSVTIPIKFRHVFITGGSSGIGLALAHRAVSEGAKVSILARSTEKLAEAKRSIQLATGVEVATFSADVRDYDAVSKAIDESGPIDVLIVNQGVFIGKELEKQSPEEVKFMIDVNLTGSFNVIKAALPAMKAREGRGPASISLVSSQAGQAGIYGYTAYSASKFGLQGLAQALQQEVISDGIHVTLLFPPDTDTPGFEQELKKRPELTSIIAASSGSMKTNEVAKICFDGIKAGKFTVTCHFIGFLLSIASTGMSPQGSFWLALTEVMFGGLIRLASLVFQWQWYKTIEKWSQRNKKEVNSKLA
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).  Required for sphingolipid biosynthesis.  In plants, sphingolipids seems to play a critical role in mineral ion homeostasis, most likely through their involvement in the ion transport functionalities of membrane systems in the root.  Is stereospecific for D-erythro-DHS production and does not produce L-threo-DHS.
What are the official names of this protein?
3-dehydrosphinganine reductase TSC10B, 3-ketodihydrosphingosine reductase, KDS reductase, 3-ketosphinganine reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS9_LISIN
Sequence: MAQVQYYGTGRRKSSVARVRLVPGDGKIVINNRDWEDYIPFAALREVIKQPLVATETLGNYDVLVNVHGGGYTGQAGAIRHGVARALLQVAPEYRPALKSAGLLTRDPRMKERKKYGLKGARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NHAA1_FLAJ1
Sequence: MKLTKTFKAFFENEKSGGLLLLFVTVISLWAANSSYSAGYIAFWEKDLAGHSITHWINDGLMTIFFLLIGLELEREIYHGELSNIKNASLPIMAAFGGMLIPAATFLALNFGTSTQNGAGIPMATDIAFAIGILSLLGDKVPASLKVFLTALAVIDDLGAIIVIAVFYTTSIGFVNLAIALGIWVFLFVLNRMKVYNLIPYLIGGVIMWYFMLNSGIHATITGVILAFVIPFGDGGEKSTSYKLQHFLHQPVAFFILPLFAIANTCIAIESNWHIGLNHPNAFGIILGLVIGKPLGILLFSSIGVSAGLCALPKNLKWAHILGAGMLGGIGFTMSIFITLLAFKDPEIIVFSKIAIIIASIISGITGFVYLRYILTTNKNT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUCC_MYCBO
Sequence: MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDIKGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGHLPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLAMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGITSCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RL393_ORYSJ
Sequence: MPSHKTFQIKKKLAKKMRQNRPIPYWIRMRTDNTIRYNAKRRHWRRTKLGF
What are the official names of this protein?
60S ribosomal protein L39-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: SK1_CRYKY
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, CryKy-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLU_CELJU
Sequence: MSSMTPREIVHELDKHIVGQQDAKRAVAIALRNRWRRMQLPADMRSEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGRDVESIIRDLVDVAIKLRREQAMKAVQYRAAEAAEERILDVLLPPARDTSEEESKHESSTRQIFRKKLREGQLDDKEIEIDVAAASVGVEIMAPPGMEEMTSQLQNMFSSLGRERTKKTKMTVKKAFKQLQDEEAAKLVSEEDIKTQALETVEQNGIVFIDEIDKVARRGNVSGADVSREGVQRDLLPLIEGCTVSTKHGMVKTDHILFITSGAFHLSKPSDLIPELQGRLPIRVELQALTPDDFERILTEPKASLTEQQQALLKTEGVDIQFTQDGIRRIAETAFDVNERTENIGARRLHTILERLLEDVSFDAGNDTSSIRIDGAYVDAHLGELAKNEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1306_RICFE
Sequence: MTTFNTVTRHPNYYTSYTKIAPKDYIISRLKALKAKIAKVNPMAIRDNKWSDLHIAVGAKELKLVKALCNEKNINATDAKCRTPLELAILGNDLETVKFLVQMGGKIAPNMYGWSAIHLAIKIDNVEMVEYLYENTEFQKYDKYGYTLHDWAEAMGRGEIVRFFHDKNHNNKTPLELAVESKNISSVKALIIKGAKFDIKSELGYKIFELAIDSEDMKLIEYLVNHTLVGKNTGQQTLLEKVAQIYDKNINLSKLVKVLIKDNAGFDKALGQKLLQKAIYADDLELVETLYSKGVDAQYKDQLGRSGLHHAIKANCGEELIQFLIEHTTDINYRDKSGLNPLGLAKSNNCTVATKLLLEAGAYESYMYDDVIKVLGEYGY
What are the official names of this protein?
Putative ankyrin repeat protein RF_1306.
Protein: DAPF_WOLTR
Sequence: MSSQSPKRMYGTGNNFVIIDSRSINNLNWNYREIANQNGCDQIIVITNSSAADCFMHIYNADGGEVEMCGNAARCVGYLIMSEKSTEYATIELVNKRILECFKVGGRSIKVNMGKPLFKWHEIPLSAKCDPLHLPIELEMLKDPVAVNIGNPHMVFFVDNISEIPLQSLGPKLEKHTLFPKKVNVNIAQVEKSGEISLRVWERGTGITASCGSAACAALIASVLRGYLITRQTSVNLPGGKLLIEWPDNIFMTGDIGFL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL_CAEVC
Sequence: TRNHMSQLWKERTYAKRMQRKERHKGKTAGKREEGDTCGAVRSSYGITSAPPMVQVRIGSQQRNLLFDTGADRTIVRWHEGSGNPAGRIKLQGIGGIVEGEKWNNVELEYKGETRKGTIVVLPQSPVEVLGRDNMARFGIKIIMANLEEKRIPITKVKLKEGCTGPHVPQWPLTEEKLKGLTEIIDKLVEEGKLGKAPPHWTCNTPIFCIKKKSGKWRMLIDFRELNKQTEDLTEAQLGLPHPGGLQKKKHVTILDIGDAYFTIPLYEPYREYTCFTLLSPNNLGPCKRYYWKVLPQGWKLSPSVYQFTMQEILEDWIQQHPEIQFGIYMDDIYIGSDLEIKKHREIVKDLANYIAQYGFTLPEEKRQKGYPAKWLGFELHPQTWKFQKHTLPELTKGTITLNKLQKLVGELVWRQSIIGKSIPNILKLMEGDRELQSERKIEEVHVKEWEACRKKLEEMEGNYYNKDKDVYGQLAWGDKAIEYIVYQEKGKPLWVNVVHNIKNLSIPQQVIKAAQKLTQEVIIRTGKIPWILLPGKEEDWRLELQLGNITWMPKFWSCYRGHTRWRKRNIIEEVVEGPTYYTDGGKKNKVGSLGFIVSTGEKFRKHEEGTNQQLELRAIEEALKQGPQTMNLVTDSRYAFEFLLRNWDEEVIKNPIQARIMEIAHKKDRIGVHWVPGHKGIPQNEEIDKYISEIFLAKEGEGILPKREEDAGYDLICPEEVTIEPGQVKCIPIELRLNLKKSQWAMIATKSSMAAKGVFTQGGIIDSGYQGQIQVIMYNSNKIAVVIPQGRKFAQLILMDKKHGKLEPWGESRKTERGEKGFGSTGMYWIENIPLAEEDHTKWHQDARSLHLEFEIPRTAAEDIVNQCEICKEARTPAVIRGGNKRGVNHWQVDYTHYENIILLVWVETNSGLIYAEKVKGESGQEFRIKVMHWYALFGPESLQSDNGPAFAAEPTQLLMQYLGVKHTTGIPWNPQSQAIVERAHQLLKSTLKKFQPQFVAVESAIAAALVAINIKRKGGLGTSPMDIFIYNKEQKRINNKYNKNSQKIQFCYYRIRKRGHQESGKDQPRYCGKGKEPIVVKDIESEKYLVIPYKDAKFIPPPTKEKE
What is the function of this protein?
During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme.  RNase H activity is associated with the reverse transcriptase.
What are the official names of this protein?
Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
Protein: SYA_THEVO
Sequence: MEKQTGELDLKFFKNNGFEKKICRVCGSYFWTTDSRRETCGDTPCDEYTFIGNPPVPKKYTLSEMRKAFFDFFEKRGHKLLEPYPVVPRWREDVLLVNASIYDFQPHVTSGIVKPPGNPIVMSQPSIRMNDVDLVGVTGRHLTSFEMLCHDAFNSKNDFVYWKEETVRYSYEFLTDGLGIDGSLITYKEKPWSGGGNAGNALEVFVRGLEVATLVFMDMKEDQEGEVEIEGTRYTKMDMQIVDTGYGLERLTWLSQGTPTVYQAIYPEIIDYVLENSYVESIDNEFLSDVVRVSVMREPYDEAFVLSTLGEKYPNALERFEKAKKVRDIFVLIDHARSLMHMFEAFVIPSNVKVGYLARLLIRRSIRAQKNIGFKGSLINLIERNYNELKDIVKPLPIEFIKDVLSIEMQKYSELEKRGQQVIEKILKTKKSIDIDDLVLLYDSHGISPDVVAAMAAEKGLKVMIPPNFHAMVISRHEKKSALKKSAKVYPNIETRTLYYDDSTMREFTGLVMYSKGNEVILDKTAFYPEGGGQPADHGYFEFKGKKINVLDVQKHGNAIVHKLDGEIPEGVRVKGVIDWERRSRLMVHHTATHLLLGVLRDILGDHVWQSGVQKDVSESHLDITHYKRIDEDTIKKIEHRIFELITEGRPVSVKNLDWYMAIGKYGFRLFEGGVPLSPKVRVVEIEGVDAEGCGGTHLKNISSIGVLKIKKIEAIQENIYRITFVAGVPALELFEDSYDLAYRVSNISKKNIDQAGDFVENTVRELSKIKRDLDSARTKLIEEEIRKSNSIKLGEKEIPAIEAETSDIDIVSRIAHSKGIEVIIESRVGTKFRYTAISPSGKSKQILHDLLHTDAEGNDKLSYVIVDHKELSITR
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.