PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_BLAGS
Sequence: MAASTGKLRTLFSAHSSLSARPSSALPALRLTILRSYATTTPPDSSISNPSNPSTTVKRPPTAFKDKLNAGPAFSDFVSGKKDEPLDPAEAYALKTALVGPAGRKKEITRLPSWLKTPIPDSSNYKRIKNDLRGLNLHTVCEEARCPNISDCWGGSSKSAATATIMLMGDTCTRGCRFCSVKTSNKPPPLDPHEPENTAEALSRWGLGYVVLTSVDRDDLADGGARHFAETVLKIKQKAPNILVECLTGDYAGDLEMVALVANSGLDVYAHNVETVEALTPFVRDRRATFQQSLRVLKAAKATKPELITKTSLMLGLGETEAQLWDTLRALRAIDVDVVTFGQYMRPTKRHMAVHEYVRPDVFDMWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKKRGKNVGSASGKGTTSENVEKLVAGEAVR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPA2_PARXL
Sequence: MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSEVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDVVKTTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKKTDAIEKIAPGVIWRKSVSEPVQTGLKSIDAMVPVGRGQRELIIGDRQCGKTAVAVDTIINQKGKNLFCIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEDYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVALFAANNGYLDDLEVAQVLPFEKGLRDYLKSKHADLIKRIEDTKELSKDDEALLHTALKDFKKSGAY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRB_BACLD
Sequence: MKHLTAMNELSLEDIHELIEEARELKKGKSDSVLSGKFAANLFFEPSTRTRFSFEVAEKKLGMNVLNLDGVSTSVQKGESLYDTVKTLESIGADVCVIRHSHDHYYDELIGHVGIPVINAGDGCGQHPTQSLLDLMTIHEEWGRFAGLTVSIHGDIKHSRVARSNAEVLTRLGAKVLFSGPDEWRDEDNPYGTYVSPDEAVAHSDVVMLLRIQHERHEKKAAERDYLETFGLSLKRAELLKKDAVIMHPAPVNRGVEIDSALVESGRSRIFKQMENGVYIRMAVLKRALLNGENKKRGDQAYVLFN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CYOE_ECO57
Sequence: MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLVGVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLWFGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDSGAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAVATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALSVMMSVDFMVPDSHTLLAAVW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_YERP3
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIPEAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HM14A_CHICK
Sequence: MPKRKAPAEGEAKEEPKRRSARLSAKPAPPKPEPKPKKAAPKKEKAANDKKEDKKAATKGKKGAKGKDETKQEDAKEENHSENGDTKTNEAPAAEASDDKEAKSE
What is the function of this protein?
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer.  May be involved in the process which maintains transcribable genes in a unique chromatin conformation.
What are the official names of this protein?
Non-histone chromosomal protein HMG-14A.
What is the protein family that this protein belongs to?
Belongs to the HMGN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATB_MYCGI
Sequence: MFANVGWGEMLVLVIAGLVILGPERLPGAIRWTAGAVRQARDYITGATSQLREDLGPEFDDLREPLSELQKLRGMTPRAALTKHLLDGDDSIFTGRFDSTSSDQPGSGKPPKPQSGPGPAAASGPAATTTPASTPFDPDAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y2581_MYCTU
Sequence: MLITGFPAGLLACNCYVLAERPGTDAVIVDPGQGAMGTLRRILDKNRLTPAAVLLTHGHIDHIWSAQKVSDTFGCPTYVHPADRFMLTDPIYGLGPRIAQLVAGAFFREPKQVVELDRDGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGSGRDLLRSIVDKLLVLDDSTVVLPGHGNSTTIGAERRFNPFLEGLSR
What are the official names of this protein?
Uncharacterized protein Rv2581c.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: ARBK1_HUMAN
Sequence: MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQRGSANGL
What is the function of this protein?
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PubMed:19715378).  Key regulator of LPAR1 signaling (PubMed:19306925).  Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PubMed:19306925).  Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed:19306925).  Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).  Inhibits relaxation of airway smooth muscle in response to blue light (PubMed:30284927).
What are the official names of this protein?
Beta-adrenergic receptor kinase 1, Beta-ARK-1, G-protein coupled receptor kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Postsynapse. Presynapse.
Protein: HSP70_DAVTA
Sequence: MAPAIGIDLGTTYSCVGIYRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDSAKNQVAINPHNTVFDAKRLIGRKFQDAEVQADMKHFPFKVIEKAGKPVTQVEFKGETKDFTPEEISSMILTKMRETAESYLGGTVNNAVITVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKQEGEKNVLIFDLGGGTFDVSFLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFSNEFKRKHKKDLSDNARALRRLRTACERAKRTLSSSAQTSIEIDSLFEGIDFFTSNTRARFEEVGQDLFRGNMEPGERTLRDDKIDKSSVHEIVLGGGSTRIPKVQKLVSDFFNGKEPCKSINPDEAVAYGAAVQAAILSGDTSSKSTKEILLLDVAPLSLGIETAGGVMTALIKRNTTIPTKKSETFSTFSDNQPGVLIQVFEGERARTKDINLMGKFELSGIRPAPRGVPQIEVTFDLDANGIMNVSALEKGTGKTNKIVITNDKGRLSKEEIERMLADAEKYKEEDEAEAGRIQAKNGLESYAYSLKNTVSDPKVEEKLSAEDKETLTGAIDKTVAWIDENQTATKEEYEAEQKQLESVANPVMMKIYGAEGGAPGGMPGQGAGAPPPGAGDDGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein, Allergen Cla h IV.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYT_STRSV
Sequence: MIKITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKLIDTTRAITEDGAIEIVTPDHEDALDILRHSAAHLFAQAARRLFPDIHLGVGPAIQDGFYYDTDNEAGQISNEDLPRIEEEMKKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDEGGLTIYRQSEYVDLCRGPHVPSTGRIQIFHLLNVAGAYWRGNSDNAMMQRVYGTAWFDKKDLKKYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATVRRELERYIVDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPMNCPHHIQVYKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTPEQIQEEFQRALQLIIDVYADFNLTEYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAALDEMGVDFFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYVGADGEEHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEAHIDYAWQVAKKLRDKGVRADVDERNEKMQYKIRASQTSKIPYQLIVGDKEVEDGTVNVRRYGQKETHTVAVDEFVEQILADIASKSRLEK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC24A_MOUSE
Sequence: MAQPRIPAARGAAASLQAQNGAASASGSPYTNGPVHNTLMSPQVSSSQGYDSQPPGSYPRPMPAKTLNPFSAQSNYGGSQGSGQTLNSPLVTSGPVLPSLHSGPVPRMPLPTSQNPAATPMPSGSFLPGANPPPPLNWQYNYPSTGPQTNHFPHVAPPTLPGNPNLTADHQYVSSGDPALQTSFKKPGSALPLQNPPLPPTFQPGAPPGPPPAGGPPPSRGPAPQKTPPRAAPPPSFNSAVNQEGITSNANNGSTAAHNTYDEIEGGGFLATPQLVNQNPKTSRSVGSAYPSLPPGYQNSAPPVAGMPPPSLSYPSGPQAFTQTPLGANHLTASMSGLSLHPEGLRVVNLLQERNMLPSTPLQPPVPNLLEDIQKLNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLVQLPVVTSSTIVRCRSCRTYINPFVNFLDQRRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLPGNTRTKIGFITFDSTIHFYSLQEGLSQPQMLIVSDIDDVFIPMPENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEIHLTPSTDFYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSSVLSGQQPGLMVPFSLRLFPLFVLALLKQKSFQTGTSIRLDERIFAMCQVKSQPLVHLMLTTHPSLYRVDNLSDEGALNINDRTIPQPPILQLSVEKLSRDGAFLMDAGSLLMLWVGRNCSQNFLSQVLGVQNYASIPQTMTDLPELDTPESARIAAFISWLREQRPFFPVLYVIREESLMKAAFLQSLVEDRTESALSYYEFLLHIQQQVNK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.  Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D.  May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
What are the official names of this protein?
Protein transport protein Sec24A, SEC24-related protein A.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.
Protein: NRDR_CHLAA
Sequence: MRCPFCHFVETDVIDTRKLYEGEVIRRRRRCRACGRRFTTYERIESVSLMVVKKDGTREPYDREKIARGVRTACYRRPVSAAAIEQLVNDVETAIMNTDEHEISSQAIGDAVMQRLRDLDEVAYIRFASVYRAFTDIGKLREAVDELLDREGVRNGHLSPKPAEDS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GLR33_ARATH
Sequence: MKQLWTFFFLSFLCSGLFRRTHSEKPKVVKIGSIFSFDSVIGKVAKIAIDEAVKDVNSNPDILSGTKFSVSMQNSNCSGFMGMVEALRFMEKDIVGIIGPQCSVVAHMISHMANELRVPLLSFAVTDPVMSPLQFPYFIRTTQSDLYQMDAIASIVDFYGWKEVIAVFVDDDFGRNGVAALNDKLASRRLRITYKAGLHPDTAVNKNEIMNMLIKIMLLQPRIVVIHVYSELGFAVFKEAKYLGMMGNGYVWIATDWLSTNLDSSSPLPAERLETIQGVLVLRPHTPDSDFKREFFKRWRKMSGASLALNTYGLYAYDSVMLLARGLDKFFKDGGNISFSNHSMLNTLGKSGNLNLEAMTVFDGGEALLKDILGTRMVGLTGQLQFTPDRSRTRPAYDIINVAGTGVRQIGYWSNHSGLSTVLPELLYTKEKPNMSTSPKLKHVIWPGETFTKPRGWVFSNNGKELKIGVPLRVSYKEFVSQIRGTENMFKGFCIDVFTAAVNLLPYAVPVKFIPYGNGKENPSYTHMVEMITTGNFDGVVGDVAIVTNRTKIVDFTQPYAASGLVVVAPFKKLNSGAWAFLRPFNRLMWAVTGCCFLFVGIVVWILEHRTNDEFRGPPKRQCVTILWFSFSTMFFAHRENTVSTLGRLVLIIWLFVVLIINSSYTASLTSILTVQQLSSPIKGIESLRERDDPIGYQVGSFAESYLRNELNISESRLVPLGTPEAYAKALKDGPSKGGVAAIVDERPYVELFLSSNCAYRIVGQEFTKSGWGFAFPRDSPLAIDLSTAILELAENGDLQRIHDKWLMKNACTLENAELESDRLHLKSFWGLFLICGVACLLALFLYFVQIIRQLYKKPTDDAIARDQQQNHDSSSMRSTRLQRFLSLMDEKEESKHESKKRKIDGSMNDTSGSTRSRGFDRERSFNSVNPLD
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel, at least in roots and hypocotyls (Probable).  Can be triggered by Ala, Asn, Cys, Glu, Gly, Ser and glutathione (a tripeptide consisting of Glu-Gly-Cys) (PubMed:18162597).  Mediates leaf-to-leaf wound signaling (PubMed:23969459).  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells (PubMed:17012403).  Contributes to pathogen-associated molecular patterns (PAMP) elicitor-mediated resistance (PubMed:23952652).  Partially involved in free cytosolic calcium variations, nitric oxide (NO) production, reactive oxygen species (ROS) production and expression of defense-related genes in response to oligogalacturonide elicitors (PubMed:23952652).  Inovlved in resistance against Hyaloperonospora arabidopsidis (PubMed:23952652).  Required for glutathione-induced defense responses, and innate immunity responses against the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:23656893).  Required for the transmission of wound-induced, phloem-propagated action potential to neighbor leaves (PubMed:24716546).
What are the official names of this protein?
Glutamate receptor 3.3, AtGLR3.3, Glutamate receptor-like protein 3.3, Ligand-gated ion channel 3.3.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the plasma membrane.
Protein: RS6_LIMF3
Sequence: METRKYEITYIIRPDIEESAKSELVARFDKILADNGATVVDSADWDTRRFAYQIGKYTEGTYHIVNVTADSDASLNEFDRLAKFSDDILRHMIVKRG
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: BACT_RHILV
Sequence: ASILTNAS
What is the function of this protein?
Narrow spectrum bacteriocin, active against closely related bacterial species.
What are the official names of this protein?
Bacteriocin.
What are the subcellular locations of this protein?
Secreted.
Protein: CBID_PROMA
Sequence: MRGFTLPVWVVAAAKAAVKVLIGESWQSHEVIELLNNEESIVVPIRSASILDNGEKALGITNCDPGECLDLTRGLEIWVCLRYIENQQIISSDGLELEPWLKIIPGYGVGKFDLTNDISISEFARQLLIVNLKPYRKEGYSLNLEIIFPSGQELAEKTSNHAFGVVDGLALIGTQADVQESASPKKLQSTIHALRSRCAESSFTGSLIFVIGENGLDLALQYGIDSSKIIKTGNWLGPLLVAAAQEKVQQLLIFGYHGKLIKLAGGVFHTHHHLADNRLETLIAFAVKERIPLSLIKEFEEAVSIEAALSILENKDISTAKKLWKRLAVEIEKRSIDYVKRYETSSIEIGAVMFDRARKIRWAGNYALKQINSFGLKLEDY
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: TADA1_HUMAN
Sequence: MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC
What is the function of this protein?
Probably involved in transcriptional regulation.
What are the official names of this protein?
Transcriptional adapter 1, SPT3-associated factor 42, STAF42, Transcriptional adapter 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TADA1 family.
Protein: EFP_NITWN
Sequence: MRVIASSIRKGNVIEQDGKLYVVLTAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVERATIEDHNFTFLYEDGDGFHFMNAETYDQVQVPKDIVGSAAPYLQENMVVKLSLHDMVPVAITLPQRVTLEVVETEPVTKGQTASSSYKPAVLSNGVRTGVPPHVAVGTRVVVMTEDGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_STAA8
Sequence: MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RUTD_ECOSM
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSRHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAACKELL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: MFD_STAAB
Sequence: MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKYAQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERIRTLTALAQGKKGLFIVPLNGLKKWLTSVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGYKRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNIEEVDITTASDYIITEEVIRHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDHQILRRLVAFMYETPSTIIDYFQKDAIIAVDEFNRIKETEESLTVESDSFISNIIESGNGFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMRSEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLSEGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGVGRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGSEWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQAKSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKDLGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIAVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTEYIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHSGITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQWLDSLKFLVKCIEESMRISDEA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_THERP
Sequence: MSWFITFEGPEGAGKTTQCALLAARLREAGYSLLVTREPGGTPLGETIREWLLAGEALRPETEALLFTAARAEHVWDRIRPALERGTIVLCDRYVDSTLAYQGAGRGLDEGWLRELHRIATGDLWPDLTILLDVPVEVGLARRRAAAATITRLDQEELAFHRRVRAWYHAAAQRDPQRWRVVDATLPPEVVADAVWATVTEVMKRGRRSP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NQRD_PHOLL
Sequence: MADSKEIKRVLLGPLLDNNPIALQVLGICSALAVTTKLETALVMTIAVTLVTAFSSFFISLIRHYIPGSVRIIVQMAIIASLVIVVDQILQAYAYEISKQLSVFVGLIITNCIVMGRAEAYAMKSPPIESFMDGIGNGLGYGVILVLVGFLRELFGSGKLFGITVMESVQNGGWYQPNGLFLLAPSAFFIIGMLIWGLRTLKPAQVEKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_THEFY
Sequence: MPAELTFVAPRRTPPPRHLADLDPQERRDAVAELGEKPFRARQLAQHYFGRLEADTARMTDLPAASRERLGEALLPQLLTPVKHVTCDNGMTRKTLWRAFDGVLVESVLMRYPDRVTLCVSSQAGCGMNCPFCATGQAGLTRNLSTAEIVDQVVSSARDLARGTVAGGPGRISNIVFMGMGEPLANYKRVLAAIRRITDPVPDGLGISQRGITVSTVGLVPAIEKLTAERMQVRLAVSLHAPDDELRDELVPVNHRWKVAEVLDAAWRYADTTGRRVSIEYALIRDINDQAWRADLLGRLVAGRLAHVNLIPLNPTPGSKWTASRPEVEREFVRRLRSHGVSVTVRDTRGREIDGACGQLAASGA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.