PharMolix/UniProtQA huggingface dataset:
Protein: SERC_SALAR
Sequence: MAQVFNFSSGPAMLPTEVLKLAQQELRDWHDLGTSVMEISHRGKEFIQVAEEAEQDFRDLLSIPSNYKVLFCHGGGRGQFAGVPLNLLGDRTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPGVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHENCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAQLLYGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALTDFMIDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOX29_ORYSI
Sequence: MDASKYVRYTPEQVEALERLYYECPKPSSLRRQQLVRECPALANVDPKQIKVWFQNRRCREKQRKESSRLQALNRKLTAMNKLLMEENDRLQKQVSQLVYDHGRHGVAAAGMMRRVPAFPPQAAAAAGHQLATATDTSCESVVTSGHHHQQQQHNVVQPPPRDASPAGLMSIAEETLTEFLSKATGTAVEWLQMPGMKPGPDSIGIIAISHGCAGVAARACGLVGMEPAKVAEILKDRPLWLRDCRSMDVVNVLPAGANGTIELLYMQLYAPTTLAPARDFWLLRYTSILDDGSLVVCERSLSSKQGGPSMPLVQPFIRGEMLPSGFLIRPSDGGGSVIHIVDHMDLEPWSVPEVVRPLYESSAMVAQKISMAALRYLRQVAHEDTRSVITGWGRQPAALRALSQKLTRGFNEALNGLADDGWSVIESDGVDDVCISVNSSKVIGCNATFSSGLPIVSTGVLCAKASMLLQDVSPPSLLQFLREHRSQWADSNLDAFFASAMKPNFCNLPMSRLGGFSGQVILPLAHTFEPEEFLEVIKLGNASNYQDTLVHRDLFLLQMYNGVEESSAGTCSELIFAPIDASFSDDSPLLPSGFRIIPIDSPLDTSSPNCTLDLASTLEAATPRSRISGVNGGGGTCAAAAASSSSKAVMTIAFQFAFDGHLQDSVAAMARQYMRNIISSVQRIAVALSSSRLVPPGAAAAAAQLSPVTPEAATLPRWICQSYRFHFGAELIKSVDANSSNESILKAVWHHPSAILCCSLKAMPVFTFANQSGLDMLETTLVALQDMTLEKVFDDQGRKNLCTELPNIMEQGMACMEGGVCVSSVGRAASYEKAVAWKVVDGDGGGAHCISFMFINWTFL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX29, HD-ZIP protein HOX29, Homeodomain transcription factor HOX29, OsHox29.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class III subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCNB1_CARAU
Sequence: MALRVTRNTRLASSENQGALPGKAAVANKPGLRPRAALGEIGNNPQTRQALRKKEVKVAPKVEAVAEKAPVVQQPKKESPKVQHDVQILSEPSSPVPMETSGCASDDLCQAFSDVMLNIKDVDADDYDNPMLCSEYVKDIYLYLRQLEIEQAVRPKYLEGSEVTGNMRAILIDWLVQVQIKFKLLQETMYMTVAVIDRFLQDHPVPKKQLQLVGVTAMFIASKYEEMYPPEIADFAFVTDRAYTTGQIRDMEMKILRVLDFSFGKPLPLQFLRRASKIGDVTAEHHTLAKYFLELTMVDYDMVHFPPSQVASARYALTLKVFNCGDWTPTLQHYMGYTEDSLVPVMQHIARNVVRVNEGLSKHLAVKNKYSSQKQMRIASISQLKSSLIKDLAKQIS
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: YZ13_AQUAE
Sequence: MKNVSPRRNKHYKSYKPQVPLKKPVLLPQHPPYRNRRKKKYQQNKYFPDFTFLLSYPVIKIRKVALKKLQKLPHKNDFNLANSLQNCQLGQNATNLILLLLFSLDHYTPLILNLAFSLTDFSKSSNCFINLSKVYPPLKPFP
What are the official names of this protein?
Uncharacterized protein aq_aa13.
Protein: IQD10_ARATH
Sequence: MGSGWLLRSIICLNGTKKNKSNRGNVHSETSNRVKPVESSSAASTKLTVEVAVIRIQKAFRAFKARKRLCSLKSARRFNSLIQGHTVMNQTSTALNVIHSWYDIQNQIRARRLYMVTQGRLQHKRLENRLKLEIKLHELEVEWCGGSETMEEILAKIQQKEEATVKRERAMAYAFSHQWRANATQYLGQASFNLGKESWGWSWKERWIAARPWEIRAQCYVVKPIKPSKKPEKSSPNNVITKTSAKPDEVGNSKKPGSG
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 10, AtIQD10.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton.
Protein: TPIC_ARATH
Sequence: MAATSLTAPPSFSGLRRISPKLDAAAVSSHQSFFHRVNSSTRLVSSSSSSHRSPRGVVAMAGSGKFFVGGNWKCNGTKDSIAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTDRIDISGQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFATIVNSVTSKKVAA
What are the official names of this protein?
Triosephosphate isomerase, chloroplastic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIPK4_HUMAN
Sequence: MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNRIIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEEKEAAGMGSVAGSSPFFREEKAPGMQRAIDQLDDLSLQEAGHGLWGETCTNAVSDMMVPLKAAITGHHVPDSGPEPILAFYSSRLAGRHKARKPPAGSKSDSNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQRDEDGPNIDNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQHGPPRGATSFLQHVTGHH
What is the function of this protein?
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity).  May act as a corepressor of transcription factors (Potential).
What are the official names of this protein?
Homeodomain-interacting protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_MYCBP
Sequence: MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNATYRNHGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDRGTSYRSAIFYFDEQQKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHFVRPGWRLPRRTAESALRASLSPELGT
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: SYDND_RHOJR
Sequence: MLRTHLAGSLRAEQAQQTVTLTGWVARRRDHGGVIFIDLRDASGVSQVVFREGAAAEQAHRLRAEYCVKVTGVVEVRPEGNQNFEIPTGAIEVNVTDLEVLNESAPLPFQLDDQAGEEARLKYRYLDLRREGPGHAIRLRSKVNAAARAVLAHHEFVEVETPTLTRSTPEGARDFLVPARLQPGSFYALPQSPQLFKQLLMVGGIERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVNQDDVILLAEEVLSSLWKLVGHEIKTPIARMTYAEAMRRYGSDKPDLRFGVELVECAEFFKDTTFRVFQQEYVGAVVMPGGASQPRKQLDAWQEWAKQRGAKGLAYVLVGEDGTLGGPVAKNLTDTEREGLAAHVGAKPGDCIFFAAGTTKSSRALLGAARGEIARKQNLIDPDAWAFVWVVDAPLFEPTADATASGDVALGYSAWTAVHHAFTSPKPESIDTFDTDPGSALAYAYDIVCNGNEIGGGSIRIHRKDIQERVFKVMGISHEEAEEKFGFLLDAFAFGAPPHGGIAFGWDRITALLAGVDSIREVIAFPKSGGGVDPLTNAPAPITAQQRKESGVDAKPEPKGDAASAKPDAPADK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDCC_YERE8
Sequence: MHIDNAITTTIETKTWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILIMLVLAYPIAFLCHRALARLCLSGSNCSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQLAPLNRGVVALALLLLMAVVIYFGKDLMVKVMSFLVFPFIACLVLISLSLIPYWNASVIEQVDLSQISLLGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEPEFGREYTEKKCSQIISRASILMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLANHFSSMAGSRSTFSITLEYAASLIALVAIFKSFFGHYLGTLEGLNGLVIKFGYKGDKTKISSGKLNLISMFFIMGSTWLVAYINPNILDLIEAMGAPIIASLLCLLPMYAIHKLPSLARFRGRPENYFVTIVGLLTIFNIVYKLL
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUCB_ECOLX
Sequence: MFALIDVNGMYASCEQAFRPDLANRAVAVLSNNDGNIVARNYLAKKAGLKMGDPYFKVRPIIERHNIAIFSSNYTLYASMSARFAAVVESLASHVEQYSIDELFVDCKGITAAMSLDAFGRQLREEVRRHTTLVCGVGIARTKTLAKLCNHAAKTWPATGGVVALDDGARLKKLMSILPVAEVWGVGHRTEKALATMGIKTVLDLARADTRLIRKTFGVVLERTVRELRGEACFSLEENPPAKQQIVVSRSFGQRVETLTDMQQAVTGFAARAAEKLRNERQYCRVISVFIRTSPYSVRDTQYANQATEKLTVATQDSRTIIQAAQALARIWREDIAYAKAGVMLADFSGKEAQLDLFDSATPSAGSEALMAVLDGINRRGKNQLFFAGQGIDNSFAMRRQMLSPDYTTDWRSIPIATIK
What is the function of this protein?
Involved in UV protection and mutation.
What are the official names of this protein?
Protein MucB.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
Protein: BLTR_BACSU
Sequence: MSEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISLFKELGVPLKEIKCLIKGKTPDKILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALETDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHEVQQYELDEGYPIGGIFAREQILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQIGENAYEEYMLDEMVVDGYENTYAKILLQVKEV
What is the function of this protein?
Activates transcription of the blt gene in response to structurally dissimilar drugs.
What are the official names of this protein?
Multidrug-efflux transporter 2 regulator.
Protein: LAC1_PYCCI
Sequence: MSRFQSLLSFVLVSLAAVANAAIGPVADLTLTNAAVSPDGFSREAVVVNGITPAPLIAGQKGDRFQLNVIDNLTNHTMLKTTSIHWHGFFQHGTNWADGVSFVNQCPIASGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPQASLYDIDNDDTVITLADWYHVAAKLGPRFPLGADATLINGLGRSPGTTTADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNTQPLEVDSIQIFAAQRYSFVLDASQPVDNYWIRANPAFGNVGFAGGINSAILRYDGAPEVEPTTTQTTSTKPLNEADLHPLTPMPVPGRPEAGGVDKPLNMVFNFNGTNFFINNHSFVPPSVPVLLQILSGAQAAQDLVPDGSVYVLPSNSSIEISFPATANAPGTPHPFHLHGHTFAVVRSAGSSEYNYDNPIFRDVVSTGQPGDNVTIRFQTNNPGPWFLHCHIDFHLEAGFAVVLAEDTPDTAAVNPVPQSWSDLCPIYDALDPSDL
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products (By similarity).  Cleaves the C-C and C-O bonds of some phenolic lignin model compounds (such as O- and P-quinols, aminophenols and phenylenediamine) (PubMed:8919775).  May also be involved in synthesis of phenoxazinone pigments (PubMed:9572949).
What are the official names of this protein?
Laccase, Benzenediol:oxygen oxidoreductase, Diphenol oxidase, Ligninolytic phenoloxidase, Urishiol oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_BURVG
Sequence: MARTQAEPPASQPDARAAWLRDQLERANYAYYVLDQPDLPDAEYDRLFGELQQLEADHPELVTPDSPTQRVGGAVASGFTPVVHDAPMLSLNNGFSDDDIVAFDKRVADALDKPTDLAGSVTDPVEYACELKFDGLAISLRYERGVFVQASTRGDGTTGEDVTENVRTIRSIPLKLKGAHVPALLDVRGEVLMFKRDFARLNERQRAAEQREFANPRNAAAGSLRQLDPKITAQRPLSFFSYGIGVLDGMPMPDTHSALLDWYEALGLPVNRERAVVRGAQGLLEFFRKVGERRESLPYDIDGVVYKVNRRDEQDRLGFVSRAPRFALAHKFPAQEALTKLVAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVGALLERRPVDAAEFVMPTECPVCGSKIERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVELNLVRTPADLFNLGFATLAELDRFAEKSAQNLLDSLEKAKHTTLARFIYGLGIRHVGESTAKDLAKHFGSLDPIMDASIEELLEVNDVGPIVAESIHQFFAEEHNRTVIDQLRAPGKVTWPEGPPAPKAPQGVLAGKTVVLTGTLPTLTRDAAKEMLEAAGAKVAGSVSKKTDYVVAGAEAGSKLAKAEELGIPVLDEDGLHQLLEGNTQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y867_TREPA
Sequence: MRWLCRLIGYRYGYAVCGGYRRQGGRCSAQLHAQYTRVSHCVLRIAWEVNGADYELFRLWI
What are the official names of this protein?
Uncharacterized protein TP_0867.
Protein: FRI3_ARATH
Sequence: MLLKAASTFSLLNIHGEKKDISPLFSSSSSISSPVSSGKSGNLSFPLRASKSSTTTTSTLSGVVFEPFEEVKKEMDLVPSGQQLSLARHLYSPECEAAVNEQINVEYNVSYVYHALYAYFDRDNVALKGLAKFFKESSVEEREHAELLMEYQNKRGGRVKLQPMVLPQSEFDHPEKGDALYAMELALSLEKLVNEKLLNLHSVASKNDDVQLADFIESVFLNEQVEAIKKISEYVSQLRRLGKGHGTWHFDQELLGAAA
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin-3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPO2N_METVS
Sequence: MESRVIVDAFFRENSLVKHHIDSYDDFVENKIQGIIDEVTGVETEIKGGYKVSFGKVRVTKPINKEADGSVKEITPMEARIRNLAYSAPLYLEMIPLIGEGDEEKTLSPIEVYIGELPVMLGAKICHLSGKSEEDMINYGEDPKDPLGYFIVNGSEKAVVAQEDLIPNRILCEKVEKNNKIVDIAKVFSTRHGFRALCTVERSPDGLLNVSFPGMPSTIPLVILMRALGAESDREIMELISDEPTVVMQLVANLQEAREEHGINTTEDALEHIGKRVAPGQPKEYKLKRAETILCNYLLPHMGIESEKLGAKCKYLGRMAKNSIELYLGSRVEDDKDHYANKRLKLAGDLMEDLFRHSFNQLIKDIKYQLERQAIRNKEPSIQAAVRSDVLTERMRHAMATGNWVGGRTGVSQLLDRTSYLATVSQLRRVVSPLSRSQPHFEARDLHATQWGKICPSETPEGPNCGLVKNLAVMCKVTTDEEDEGIIQLIKEIGLSKDI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  The Rpo2 subunit (Rpo2N and Rpo2C in this organism) is implicated in DNA promoter recognition and in nucleotide binding.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo2N, DNA-directed RNA polymerase subunit B''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLE12_ARATH
Sequence: MLRISSSSSMALKFSQILFIVLWLSLFFLLLHHLYSLNFRRLYSLNAVEPSLLKQHYRSYRLVSRKVLSDRFDFTPFHSRDNSRHNHRSGEQYDGDEIDPRYGVEKRRVPSGPNPLHH
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.  Represses root apical meristem maintenance.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE12p]: Secreted, extracellular space.
Protein: HTPX_THEGJ
Sequence: MGLEMWLRTGLLMAILTGLLMGIGYLFGGPQIAFIMFLFAMLFNFITYWYSDRIVLSWYNARIVDEMEAPELYAIVRSLAERAGLPTPRVAIIPTETPNAFATGRDPKHAVVAVTQGLLRILNRDELEGVIGHELTHIKNRDILIGTVAAAMAGAIMQLAYWARWIAIFGSYDDRDDGGNVLAAILVAVLAPIAAMLIQAAISRSREFLADEGGARISGKPWALASALMKIEQAVRYRPMREGNPATAHMFIVNPFRGMSIAELFSTHPPTEKRIERLRKIAEEMGYVPNF
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNHD2_STAAS
Sequence: MLSNLLILPMLLPFLCALILVFLKNNDRISKYLYLGTMTITTIISLMLLIYVQRHRPITLDFGGWSAPFGIQFLGDSLSLIMVTTASFVITLIMAYGFGRGEHKANRYHLPSFILFLSVGVIGSFLTSDLFNLYVMFEIMLLASFVLITLGQSVEQLRAAIIYVVLNIIGSWLFLLGIGLLYKTVGTLNFSHIAMRLNDMGDNRTVTMISLIFLVAFSAKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDQHNDLIHPLLATMAAITMVIGAIGVIAYKDIKKIAAYQVIISIGFIILGLGTNTFAGINGAIFYLVNDIVVKTLLFFIIGSLVYITGYRQYQYLNGLAKKEPLFGVAFIIMIFAIGGVPPFSGFPGKVLIFQGALQNGNYIGLALMIITSLIAMYSLFRILFYMYFGDKDGEEVNFKKIPLYRKRILSILVVVVIAIGIAAPVVLNVTSDATELNTSDQLYQKLVNPHLKGED
What are the official names of this protein?
Putative antiporter subunit mnhD2, Mrp complex subunit D2, Putative NADH-ubiquinone oxidoreductase subunit mnhD2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTU_AQUAE
Sequence: MAKEKFERTKEHVNVGTIGHVDHGKSTLTSAITCVLAAGLVEGGKAKCFKYEEIDKAPEEKERGITINITHVEYETAKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHVLLARQVNVPYIVVFMNKCDMVDDEELLELVELEVRELLSKYEYPGDEVPVIRGSALGALQELEQNSPGKWVESIKELLNAMDEYIPTPQREVDKPFLMPIEDVFSISGRGTVVTGRVERGVLRPGDEVEIVGLREEPLKTVATSIEMFRKVLDEALPGDNIGVLLRGVGKDDVERGQVLAQPGSVKAHKRFRAQVYVLSKEEGGRHTPFFVNYRPQFYFRTADVTGTVVKLPEGVEMVMPGDNVELEVELIAPVALEEGLRFAIREGGRTVGAGVVTKILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBAD_CHICK
Sequence: MLTAEDKKLIQQAWEKAASHQEEFGAEALTRMFTTYPQTKTYFPHFDLSPGSDQVRGHGKKVLGALGNAVKNVDNLSQAMAELSNLHAYNLRVDPVNFKLLSQCIQVVLAVHMGKDYTPEVHAAFDKFLSAVSAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: EGR1_HUMAN
Sequence: MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGAPEGSGSNSSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISLNNEKVLVETSYPSQTTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAASSASASQSPPLSCAVPSNDSSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAYPAAKGGFQVPMIPDYLFPQQQGDLGLGTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSGSQDLKALNTSYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKSVVASSATSSLSSYPSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSSTYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVTNSFSASTGLSDMTATFSPRTIEIC
What is the function of this protein?
Transcriptional regulator (PubMed:20121949).  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity).  Binds double-stranded target DNA, irrespective of the cytosine methylation status (PubMed:25258363, PubMed:25999311).  Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia.  Plays a role in the regulation of cell survival, proliferation and cell death.  Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation.  Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy.  Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia.  Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (By similarity).  Regulates the amplitude of the expression rhythms of clock genes: BMAL1, PER2 and NR1D1 in the liver via the activation of PER1 (clock repressor) transcription.  Regulates the rhythmic expression of core-clock gene BMAL1 in the suprachiasmatic nucleus (SCN) (By similarity).
What are the official names of this protein?
Early growth response protein 1, EGR-1, AT225, Nerve growth factor-induced protein A, NGFI-A, Transcription factor ETR103, Transcription factor Zif268, Zinc finger protein 225, Zinc finger protein Krox-24.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NEC1_ALHV1
Sequence: MHKIQKMSCTPSVRSRYTLKRKRLNSAKSATLKKKKVFLSNSEFFAGVSTNYELGKDFLREMDTPICTSNTVFLPVKFSDVAPGRCLTLSPYGHSSVLGFHCQECKPDSSSGFTQAQQSAESNELLSVNLCFLNNVEKVVQHKAFYLSLLGHSMNTVKQSLGQPSLLYCYTVLKKFYPQIFPIFTANGPMLTMYIIFTSLTLHVSEAVLRILTDNVENHNLSADCYKGHYILSIEPQALEESNLNVCVTKICDLVAQLDFSDELKQEYVNGSTLIANFLN
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC1 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane. Note=Remains attached to the nucleus inner membrane through interaction with NEC2.
Protein: PUS7L_HUMAN
Sequence: MEEDTDYRIRFSSLCFFNDHVGFHGTIKSSPSDFIVIEIDEQGQLVNKTIDEPIFKISEIQLEPNNFPKKPKLDLQNLSLEDGRNQEVHTLIKYTDGDQNHQSGSEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIGRILDKNQRASLHSAIRQKFPFLVTVGKNSEIVVKPNLEYKELCHLVSEEEAFDFFKYLDAKKENSKFTFKPDTNKDHRKAVHHFVNKKFGNLVETKSFSKMNCSAGNPNVVVTVRFREKAHKRGKRPLSECQEGKVIYTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKEIEKKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLKKQINDSANLRERIMEAIENVKKKGFVNYYGPQRFGKGRKVHTDQIGLALLKNEMMKAIKLFLTPEDLDDPVNRAKKYFLQTEDAKGTLSLMPEFKVRERALLEALHRFGMTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETYGARVVQGDLVCLDEDIDDENFPNSKIHLVTEEEGSANMYAIHQVVLPVLGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPTLKLNIPGCYRQILKHPCNLSYQLMEDHDIDVKTKGSHIDETALSLLISFDLDASCYATVCLKEIMKHDV
What is the function of this protein?
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.
What are the official names of this protein?
Pseudouridylate synthase PUS7L, Pseudouridylate synthase 7 homolog-like protein.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: APQ12_SCHPO
Sequence: MSLTSVLWNFVAKLAVDHGLNTNPDQVFQTVENVGKSFEKYETSFLKSLFNGNLGLSLPSAINILTLIIVLYFSLVIVNKTTSIALALFKTLAVISFFLLIGCLFAYWFINNGSF
What is the function of this protein?
Involved in the regulation of lipid homeostasis in the endoplasmic reticulum, thereby impacting nuclear pore complex biogenesis and localization, and nucleocytoplasmic mRNA transport.
What are the official names of this protein?
Nuclear membrane organization protein apq12.
What is the protein family that this protein belongs to?
Belongs to the APQ12 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YQJE_ECO57
Sequence: MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
What are the official names of this protein?
Inner membrane protein YqjE.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.