PharMolix/UniProtQA huggingface dataset:
Protein: URED_STAS1
Sequence: MSNNKQAWTGQLDLSVFNNGKKSVARDVFFEKALKVMRPVYLNQSDIPTFYIVNVGGGYLDGDRYTMNFNIDSDAKVILTSQGATKIYKTLNDHVEQYQTFNIKNNGYAEYVGDPIIAFENAKFYQHNVFNLESTASLFYTDILTPGYSKSDKRFSYTYMHLLNEIYVDDALVTFDNMLLDPQKQNVDGLGYMEDYTHLGSCYFIHPSVNQKFIEQVYEEIKHFQHKYDCRFGITHLPTHGFSLRILSNKTQVIESIITAVQCYVVKQIFDRDVDFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1C_SYNP2
Sequence: MNSGIDLQGSFIETLQSFGLSHEIAKTIWLPLPLLLMIIGATVGVLVVVWLERKISAAAQQRVGPEYAGPLGVLQPVADGLKLVFKEDVVPAKTDPWLFTLGPALVVIPVFLSYLIVPFGQNLVITDLNVGIFLWISLSSIAPIGLLMSGYSSNNKYALLGGLRAAAQSISYEIPLALAVLAIAMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEELVAGYQTEYAGMKFGLFYVGSYVNLVLSALIVSILYLGGWEFPIPLDKLAGWLNVAPSTPWLQVITASLGIIMTLVKTYALVFIAVLLRWTLPRVRIDQLLNFGWKFLLPVALVNLLLTAALKLAFPIAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CH602_PAEAT
Sequence: MAKQLAFNDAARRSLEAGIDKLANTVKVTLGPRGRNVVLDKKWGAPTITNDGVTIAREVELDDPYENLGAQLAKEVATKTNDVAGDGTTTATVLAQALVKEGLRNVAAGAAPGEIKRGIEVSVEAVAARLLENAREVEGTQVASVAAISAQSDEVGELLAEAFGKVGKDGVITIEESSTTQTELVLTEGMQFDKGYLSPYFVTDAERQEAVLEDALILINQGKISSLQDFLPLLEKALQANKPLFIIAEDIEGEALSTLIVNRIRGTLNVVAVKAPGFGDRRKAMLQDIATLTGAQVVSPDLGLTLDTVGLEVLGTARRITVTKDNTTIVDGAGTAQDVADRVAQLRAELTRTDSDWDKEKLQERLAKLAGGIGVIKVGAATEVELKEKKHRIEDAVSSTRAALEEGIVSGGGSALIHALKALDESPAVKALEGDAAAAVGIVRRALVQPLRWIAQNAGFDGFVVVAKVSELEANHGFNAKSGEYEDLIAAGVIDPVKVTRSALRNAASIAALVLTTETLVAEKPAEEEDAHAGHQH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_MARN8
Sequence: MTPVIALVGRPNVGKSTLFNQMTRSRDALVADFPGLTRDRKYGEGNYEGQKFIVIDTGGLTGDEAGIDAEMARQSMQAVEEADIVLFLVDGRAGLTAGDEMIADYLRKSGKQAHLVVNKTDGQDPDVAAADFYSLGFESTFLIAAAHNRGILSLLEALLPEPENPEDQDRADRYPGIRIGVVGRPNVGKSTLVNRMLGEDRVVVYDMPGTTRDSVYIPYERQGHEYTLIDTAGVRRRKNVREAVEKFSIIKTLQAIDDAHVVILVIDAREGLVDQDLHLIGFVLDAGRSLVIAINKWDGMDPEDRDRVKEQVARRLDFLDYADKYYISALHGTGVGTMYESVQACYESAMSKWPTNRLTAILQDAVAQHQPPMVHGRRIKLRYAHQGGSNPPVVVVHGNQVDSLPGAYKRYLENTFRKVLKVVGAPIRFEFKSGENPFATKVDRLTPRQKVKKDNDLKKGRRIKKTRQKSVKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GCNA_DROME
Sequence: MADHKYRLFNAVDPSKVSHAPKDHPEKRNDQKTRKLPAAPMRANVGAPAPSCGANTEDTELDNSDYMEALQLSADGCSQDVANVGDVELLSAGISNLKVQPINEEHSAKPEISICISSTTEENVSGDDDAASCITISDSSEDEQEPLPPDSMAVSEREIVANPGQEDIPQPMLTTEKVQRIEAFLRDVSIERREMEWNGPLTPPPLSSSQRQSRLADADTESMSPTDEDWQPPTTRPIYNSTQLANNDTQVNTICSADATRLDSSKRLADDETEANTLGSEELEPTYSSKRLADNDTEPNTLCSDSSETHNSTIHNNEPVPDESIEIPETSSEGELTPQKASSGSSTSGGDEHGSIQVSSINISAKINIKISIPTMESSSAEDDDEHYSSPRATKSLPSSEEVQHQEHQQQDPQSHQKSMLSVDDASEDEQFLTHAEKLLNQLYGKSWQTPDVIRTLKRSSGSGGKQAPLRPRNIQATAVTTAKKKKPKPDESVLGDFSIFTKPLRTNQTPLNSTRLPPMRAVQTERRPRTQKPLTRPRTNHIDEDRWRKLIDSDSGTDASDDEDADATFSESGSDSDSDKDKENKQKRGDLTYLDLSKDEVEVISNPDQDSPSPKCHRRLDDILRSCRASVKAKLPATPVQQPNIRRQLFTPNAGFENDNQAKEIVNRALDLDMLDELESDYLPGTPVHRRVQEVKKKLGIGQQGQTTPHESPILKLLTPKTAPPKGTAPPKTSAPPKVSTPPKSTKQIPKPRKQKDLSPVASGGKCGFLKSLEGQVSRDRADNEAFFYRENFARNKDQLAQHLYKMYNAQVFNNELDVPITWSKLLRNTAGRCMNKRKLNQRSSVVELSVKVLTTADRLRCTLIHELCHAAAWVFNGEGGHGRVWKMWAQRANDKFPDLPQIKVCHNYSIEFKYTYKCLSCDKASHAHSRSRKVEDLRCRICRGPITLFLNKKDKQGNTVSTPAGEAKGFAKFVKDNFQRHKRDNMTAAQVMRILSVEYAKQKGQPAEETAASIASRVETLTLDESSN
What is the function of this protein?
May play a role in DNA-protein cross-links (DPCs) clearance, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage (PubMed:31839537).  Limits replication stress and DNA double-strand breaks (PubMed:31839537).
What are the official names of this protein?
Germ cell nuclear acidic protein, Germ cell nuclear acidic peptidase.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome. Note=During mitosis, associated with dividing chromosomes.
Protein: PORC_METTM
Sequence: MIEIRFHGRGGQGAVTAAEILAKAAFEDGKYSQAFPFFGVERRGAPVMAFTRINDEPIRRRYQVYNPDYVVVLDEGLVDVVDVFSGLKEDGVVLLNTAGTFTSENAKIHTIDATGIALENLGRPIVNTVMLGAFAGVTGLVSIDSLIKIIKETFPGKIGDKNAEAARIAYEKMKHSG
What are the official names of this protein?
Pyruvate synthase subunit PorC, Pyruvate oxidoreductase gamma chain, POR, Pyruvic-ferredoxin oxidoreductase subunit gamma.
Protein: RECA_GLOC7
Sequence: MATITNNPDKEKALNLVLNQIERSFGKGSIMRLGDAARMRVETIPSGALTLDLALGGGLPKGRVIEIYGPESSGKTTLALHAIAEVQKAGGVAAFVDAEHALDPTYSEVLGVDIHNLLVAQPDTGESALEIVDQLVRSAAVDIVVVDSVAALVPRAEIEGEMGDNQVGLQARLMSKALRKIAGNIGKSGCVVIFLNQLRQKIGVTYGSPEVTTGGTALKFYASVRLDIRRIQTLKKGSEGEYGIRAKVKVAKNKVAPPFRIAEFDIIFGKGISQMGCMIDMAEHTDVITRKGAWYSYNGENIAQGRDNAVKYLEENLDVAAIIEKQVREKLDIASLSFAGSGNDDEEEFEAVEAEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_THEP1
Sequence: MGFQIAIDGPAASGKSTVARLLAEKLGFDHLNTGATYRSVAVYLHERGFSPFSAEKEIENALKDLKIDYVNGRVYINGEDYTEKIQSPEAGVLASNFARLEVVRRHLVRIQREICDDKNIVVEGRDIGTVVLPNAHLKIFLTASLEARVERKLKEYQKRGLKVTKEEVERELISRDEQDSKRNVAPLKPAEDAVIIDTTSMSVEEVLDRILKLVRERMNT
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPID_YERPE
Sequence: MKAILQVINLVLISVVVIIIPPCGAALGRRKA
What are the official names of this protein?
ilv operon leader peptide, ilvGMEDA operon attenuator peptide.
Protein: HDED_ECOLI
Sequence: MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFVSGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPELGIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVSVTLVSTLVGIELIFSAASLFSFASLFVKQQ
What are the official names of this protein?
Protein HdeD.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURB_MYCBP
Sequence: MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ACIET
Sequence: MLDSPKLTARQQQILDLIQTAIARTGAPPTRAEIAAELGFKSANAAEEHLQALARKGVIELVSGTSRGIRLRGETVRNINAARGAQFNLPIPGLSQLTLPLVGRVAAGSPILAQEHVDQTYTVEGSLFAHKPDYLLKVRGMSMRDAGIMDGDLLAVQATREARNGQIIVARLGDDVTVKRLRRTGSAIELLPENPDYPVIRVEPGEPFEIEGLAVGLIRNTMLM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL4_YERPS
Sequence: MELVMKDAPGALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFSVEAPKTKLLAQKLKDMALEDVLIVTGELDENLFLAARNLYKVDVRDVAGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y1412_STRP1
Sequence: MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRYRLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH
What are the official names of this protein?
UPF0213 protein SPy_1412/M5005_Spy1151.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: PYRD_ANADE
Sequence: MLWPALRSVLFQLDPERVHHLAHWALHRVPPALARARRPAPVPALAVRCMGLDFDGPMGLAAGFDKGDVALPGLFGLGFSHVEIGTITPRPQPGNDRPRLFRLPEHRALLNRMGFNNEGMEACARRLAALPAAARLGPVGINVGKNKATPNEDAASDYLACIERLHPYADYLVVNISSPNTPGLRQLQEREALDRLLRACVRHLAERAPGKPLLVKLAPDLSPEALDEAVDVAIAAGAAGIVATNTTLSRAGVERHPRAAEAGGLSGAPLERLATEVVRRCYARAAGRVPIVGVGGVMDAEGAYAKIRAGATLVQAYTGLIYGGPGFVGRVNAGLARLLERDGFSTLSDAVGADHRQGGGKAAG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CLPP_NATTJ
Sequence: MNLIPMVIEQTNRGERSYDIYSRLLKDRIIFIGTGINDDIANSVIAQMLFLESEDPDKDIHLYINSPGGHVHAGLAIYDTMQYIRSDVSTICVGMAASMGAVLLAAGNEGKRFCLPNSRIMLHQPMGGAQGQAADVEIHAREIMKTKERLNQILAHHTGQPVEQISKDTDRDFFMSSEEAQKYGVIDDVLKRPPENS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2466_CLOBM
Sequence: MSGHSKWHNIQAKKGKVDAKRGKIFTKIGKEIVVAVKQGGPSADSNPRLRDVIAKAKANNMPNDTIERSIKKASGELNAVDYETITYEGYGPAGIAVLVDVLTDNKNRSAGNVRYAFTKQGGNMGSTGCVSFMFQSKGQIVIEKKDGLDEDELMMMALDAGAEDFESEDEVYVVATSQEDFGTVREALEAEGLEFLEAEIKMVPDTYTAIDEDTATKFQKMLDVLEDDDDVQNVYHNAEFPEGWEE
What are the official names of this protein?
Probable transcriptional regulatory protein CLK_2466.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUR_BRUSU
Sequence: MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYRTIKLLEERGAIHRHAFAGGPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTA_ANEVI
Sequence: MVFLLCFFLVADVSYGINGDCELPKVVGPCRGGFRRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVCGVRSRDSPKEN
What is the function of this protein?
Serine protease inhibitor that inhibits both tissue and plasma kallikreins.  Has hemolytic activity.  Inhibits voltage-gated potassium channels (Kv).
What are the official names of this protein?
U-actitoxin-Avd3m, U-AITX-Avd3m, AsKC10.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RL4_SYNSC
Sequence: MASCVVRDWQGKEAGKATLDLKVAKETTAVDLMHRAVLRQQAHARQGTASTLTRSEVRGGGRKPYKQKGTGRARQGSIRTPLKPGGGIIFGPKPRTYNLAMNRKERRLALRTALMARIDDVTVVQDFGASLEAPKTREITDALGRLGVAAGSKVLIVLTNPSDVVRRSVRNLEKVKLISADQLNVFDLLHANALVLGEEALATIQEVYGDD
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SOP4_ASHGO
Sequence: MRALLLAFQLLSVVAALTTVNCRLDLSPRQISRKDLLRTHLRLYQVGNFSGQPYSAKATLRDPEGRFRFEDLPVSHDENSTVYFQLVASSQDYNLKPNRVLIEVQGRGEGKEPTVRAFQNVFGREHFPSPEILYPEQLVELEAEPELVISYVHAAPMRNYIVSRRSGILDSGPLAGIFRSKYKMAAVVTIIALLLFPMLVEKFDPATVEAIKEQRLSQTREKYAAVGESNS
What is the function of this protein?
Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
What are the official names of this protein?
Protein SOP4.
What is the protein family that this protein belongs to?
Belongs to the SOP4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ATM1_CHAGB
Sequence: MKEMSRYLWPKDSWGDKLRVLLAVGLLVGGKVLNVQVPFFFREIVDSLNVDIAATGGTVATVAGTMIFAYGASRIGAVVSQELRNAVFSSVAQKAIRRVATRTFGHLLNLDLNFHLSKQTGGLTRAIDRGTKGISFLLTSMVFHIVPTALEISMVCGILTYQFGWEFAAVTALTMSAYTAFTIWTTAWRTKFRRQANAADNKASTVAVDSLINYEAVKYFNNEKYEIGRYDKALHQYEKSSIKVATSLAFLNSGQNIIFSSALTIMMWLGAKGIVAGSLSVGDLVLINQLVFQLSVPLNFLGSVYRELRQSLLDMETLFNLQKVNLSIKEKPNAASLVLPKGGEIRFDNVSFGYYPDRPILNNLSVTIPAGKKVAVVGPSGCGKSTLLRLLFRSYDPQSGRIFIDDQDIRDVSLDSLRRSIGVVPQDTPLFNDTVELNIRYGNLDASREKVLEAARRAHIHDKIESWPHGYQTKVGERGLMISGGEKQRLAVSRLILKDPPLLFFDEATSALDTHTEQALMSNINEVLKEKRRTSVFVAHRLRTIYDADVIIVLKEGRVVEMGSHRELMEGNGLYTELWMAQEMSMHDQSLGRSEREAPVPVK
What is the function of this protein?
Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (By similarity).  Hydrolyzes ATP (By similarity).  Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).
What are the official names of this protein?
Iron-sulfur clusters transporter ATM1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VNS3_BRD
Sequence: MLAALEMKSSPTAPPAYAAIPSTNAALSVLQNAVASGTGANEVMRNEKAAYGAATEVLKDDETTRMLKMQVNEYSLAEMRAAYQKLKRQSRLLHYGELLCLALVLGLTFTLMASSTAAVLQSALQQVGITGHVVTGILTSLAIFLQHHRTRVLKRKRSVKRDIVKRMTYISLARRMGTRSPETGCRKVTSGLPHGASGGSGTRQG
What is the function of this protein?
May play a role in the release of virions from infected cells.
What are the official names of this protein?
Non-structural protein NS3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus NS3 family.
Protein: RENBP_CANLF
Sequence: LNLVDQLGEADEELAGTYAELGDWCAQRILQHVQR
What is the function of this protein?
Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine.  Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
What are the official names of this protein?
N-acylglucosamine 2-epimerase, AGE, GlcNAc 2-epimerase, N-acetyl-D-glucosamine 2-epimerase, Renin-binding protein, RnBP.
What is the protein family that this protein belongs to?
Belongs to the N-acylglucosamine 2-epimerase family.
Protein: SYP_ENT38
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWVESGRWEQYGPELLRFVDRGERSFVLGPTHEEVITDLIRNELNSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDSYSFHTSQESLQETYDKMYEAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVIFSDTSDYAANIEFAEALAPSAPRAAASEEMKLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSAYPLVALLVRGDHELNEVKAEKLAQVASPLTFATEAEIRAVVNAGPGSLGPVNMPIPVVIDRTVAAMSDFSAGANIDGQHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLMIKRGIEVGHIFQLGTKYSEALNASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNHDERGIVWPDNLAPFQVAILPMNMHKSYRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTVVIGDRNLDSDDIEYKYRRSGEKQMIKTGDILDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIN3_CAEEL
Sequence: MYNPPPGGGGGNNGGDQSQQQPTNNATLFLLQMIQQSQHQQQHQNQQQQQLELQIRDQERILIEQQRMQHQQQQNQLLQGLNQFPFNPLGLFQVQAAVQAAQAQFAQNAQGSPIPFHIGSPLQPSHSPAASALQQQYLLPSHSPAITPFARNSEAARNIEQFIAQEEAANVPRANSQQQSPLIRPIPQQQALNIQNLTSTQQAQQILAHHRQVPVQQVQHQQHIPTPPLALPIAQQGPISNEVPSVPPVVPATSAGCPQREPRQQQGGRRQNRPGRRKKPEGPPRVDEALAYLRVIKSTFSSDVPVYHRFLEIMKDFRAQRIETPDVIEQVAELLYDSPELVLGFNTFLPTGYRITLTPDRKYVFSSPQMQPRVLLSPDERRARAIEAGAQAVGAIELGSQEGISKDEDRTIEDEDMDKSKEKDDVDGIDDEDDEESGIEDKNNEEMMEEDNHLIEEIICDDRKKDDCEDSQQEIEMSSELAAHTLNIIELLKKSFLARPTKLVDFMTFIDFFMSDQQYKKDMEKLRKDDEDDEIEENEKIEVDDVPGPSNAPQEIKKPDDIEKKDSSKNLQIEESCSDYLVSMLANCCIGEPDLLAATIDFLPYLGKLLVNGSDAIALKIKTILHFSATNDRNDIPPVNRVNPSDVDMDLVKQMEKCKMGTKKNEKLKLKVAGQGDEGATVELMILKKSYRILYERLKSRTTPNQLSHLMVLINAYANLDITREQLISELPKIMGTSGSDLEMIILQLLGAEKEPKNRPENDMDAVMRKDLPAIQPKRGLRDQKMLQQVKNVEAATVCTLGPSYRFMKDTKATDCSGRVELDDDLKGVLNDTWTSIPSWSSEDTGSQAIKKSNLEEFHFKTEDERYELDIIVDSNRTVIEQLSKTLRDYEAMSDEDKKSFKLDKWLNASSRSTTIRVLAKVFTNSAQDFIDAAQKNPLVGLRRILESLKEKDLLWSRFQQDTNRTWRDALDKQMSAATTILNNQHKNYDQKAFKSKPLVNQIEQICEERRKNNSTDTSPHLILEYTPERKVYRDVNDVTGHFFHDLSGTKCDRDRTKIVLFSYRILMEWLCQEGQQVQIDLDNGEIFKFQGDLNEDENLMTLLNMDGRRICGDRVVPVSTSLESNESSIDHFSENLHQKRTRRTFYGDDSVYMIIRYHHMIQERFAKILSTQAIYAQEHFDNQKKNKRWEDGIGADMHGRKALQENIKQRRAAVNDIRNVRSCPSSSYETTLRELKQLGNAQMDIVAFEEAVKNLFPGDIVLFNNIDKLFSSLAKNIHHATCAEERENPIKLYLKYRQRIMNAERDEDMESVIQEYGQTAEEVLRGKNTYRFEFVEEQNKPFIKIWVIPREEKDDDDDDDEEGNEGGKDEDNVKDEDDGGDGEGRDGPDDDQPPPSNDDGDDEEDEDDEEDGPSGADEPESTSGSGNVPMDHLNIGENFLWSPPEEKVCTGKMTTNEKEQRNSVDYMKVTTTPRLRIHKRMLKEHKGCNVELMTGFQQLSAIVPLM
What is the function of this protein?
Probable transcriptional repressor required for the deposition of dimethylated 'Lys-9' of histone H3 (H3K9me2) on asynapsed chromosome pairs (both autosomes and sex chromosomes) during meiosis, but this does not seem to solely affect the transcriptional status (PubMed:21909284).  Plays a role in ray fusion and patterning in the male tail, and this may be through activity of the histone deacetylase complex (HDAC) (PubMed:17506990).
What are the official names of this protein?
Paired amphipathic helix protein sin-3, Histone deacetylase complex subunit sin-3, Transcriptional corepressor sin-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIE_PSEAB
Sequence: MSQGVEFNRLMLEMRSMQMEAMAKAKPVQAPAEAGAPSFSEMLSQAVDKVNETQQASTAMANAFEVGQSGVDLTDVMIASQKASVSFQAMTQVRNKLVQAYQDIMQMPV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: OTO1_YEAST
Sequence: MNVRGNQCIMSIRVFLKAGESSLSFAIKWLKRFEATTKKNQYIQNGWPLKDGNKKRK
What is the function of this protein?
Proetin of unknown function whose overexpression causes growth inhibition.  Overexpression increases the expression of ergosterol synthesis genes.
What are the official names of this protein?
Uncharacterized protein OTO1, ORFan toxic when overexpressed protein 1.
Protein: NTC20_YEAST
Sequence: MPSLRDLSLERDQELNQLRARINQLGKTGKEEANDFVGLNISNEPVYDTVIQTGQSSNATNSFVQETIQKTKQKESGQPYIIPQKNEHQRYIDKVCETSDLKAKLAPIMEVLEKKTNEKIKGIIRKRVLQEPDRDNDDSG
What is the function of this protein?
Involved in pre-mRNA splicing.  As a component of the NTC complex, associates to the spliceosome to mediate conformational rearrangement or to stabilize the structure of the spliceosome after U4 snRNA dissociation, which leads to spliceosome maturation.
What are the official names of this protein?
Pre-mRNA-splicing factor NTC20, PRP19-associated complex protein 20, Synergistic to PRP19 mutation protein 384.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEMTB_METJA
Sequence: MKKEIIKWSKDFETGIKAFDDEHKILVKTLNDIYNLLNEGKRDEAKELLKRRVVNYAAKHFKHEEEVMEKYGYPDLERHRKTHEIFVKTVIEKLLPKIEEGSENDFRSALSFLVGWLTMHIAKPDKKYGEWFKEKGIVIEDEAVKID
What is the function of this protein?
Oxygen-binding protein.  May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes.  The oxygen-binding site contains two iron atoms.
What are the official names of this protein?
Bacteriohemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: GSPM_VIBCH
Sequence: MKELLAPVQAWWRSVTPREQKMVMGMGALTVLAIAYWGIWQPLSERTAQAQARLQTEKQLLSWVSENANDIVTLRAQGGSDAPSDQPLNQVITNSTRQFNIELIRVQPRGEMMQVWIQPLPFSQLVSWIAYLQERQGVSVDAIDIDRGKVNGVVEVKRLQLKRGG
What is the function of this protein?
Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in the complex assembly and recruits EpsL resulting in a stable complex in the inner membrane.  Provides thus a link between the energy-providing EpsE protein in the cytoplasm and the rest of the T2SS machinery.
What are the official names of this protein?
Type II secretion system protein M, T2SS protein M, Cholera toxin secretion protein EpsM, General secretion pathway protein M.
What is the protein family that this protein belongs to?
Belongs to the GSP M family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.