PharMolix/UniProtQA huggingface dataset:
Protein: RS13_TRIEI
Sequence: MARIAGVDLPRDKRIEIGLTYIYGIGLSRSQEILAETDVNPDTRVKDLSDADVAAIRSEVQNNYEVEGDLRRLEAMSIKRLMDIGTYRGRRHRMGLPVRGQRTRTNARTRRGVRRTVAGKKKASAKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: U729_DROME
Sequence: MVCVPCIIIPLLLYIWHKFVQPILLRYWNPWEKKDDDGNVIKKGPDFPFECKGGVCPFVPGGKKTENVSDDDAEESENPPLNATAMAAETEVDESKKEI
What are the official names of this protein?
UPF0729 protein CG18508.
What is the protein family that this protein belongs to?
Belongs to the UPF0729 family.
Protein: LHX3_DANRE
Sequence: MLLEHPGSSCQNAGNYTRYSSSQDIPVCAGCNQHIVDRFILKVLDRHWHSKCLKCSDCQSQLADKCFSRGDSVYCKDDFFKRFGTKCAACQQGIPPTQVVRRAQDFVYHLHCFACIVCKRQLATGDEYYLMEDSRLVCKADYETAKQREADSTAKRPRTTITAKQLETLKNAYNNSPKPARHVREQLSTETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGTSKSDKDSTQEDGMDSDAEVSFTDEPPMSDLGHSNGIYSSLSESSPALSRQGGNHPAFPLEHGAIIPSQEPYHDIQASSPYSLPQSPGPLQPLPRHQPLISSLVYPESGLPMAGQSGGQDMTPGVRMMAAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
LIM/homeobox protein Lhx3, LIM homeobox protein 3, Homeobox protein LIM-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: GTR10_DANRE
Sequence: MGCSVLLLTITVSTLGGLVFGYELGIISGALPQLQTHFSLGCVQQEAVVSALLIGSLFASIIGGWLIDRHGRRTSILLSNLLILAGSVILTTGTSFFALVIGRAVIGFAMTVSSMSCCIFVSEMVTPERRGLMVTLYEVGITVGILIAYAVNYIFNNVPLTGWRYMFGFAIIPSLIQLASIVLLPKQAEVFVIHDDDSRQADRLTEETETSNQHQQSEKYGVSDLFKSKDNMRRRTVIGVGLVLSQQFTGQPNVLFYASTILFSVGFQSNASAILASVGFGIVKVIATLLAMLCSDRAGRRSLLIGGCSMLAVGLILTGFLCRQSVIDTTKRCTSVGPHSNLTLSAEHDEGVGFSSQTLDVHEHLRSFSQSEDIYKWIIFTCLMAVVSAFSVSFGPMTWVVLSEIFPKDIRGRAFSFINCFNVGANLIVSFSFLSIIDVIGLSGVFLMYGVVGIAGVVFIYLVLPETKGKSLQDIDRELSQTRMIHRQELCSIFQRRRFSPGYQRVQLTSTAT
What is the function of this protein?
Facilitative glucose transporter required for the development of the cardiovascular system.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 10, Glucose transporter type 10, GLUT-10.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Protein: LDH1_STAAR
Sequence: MNKFKGNKVVLIGNGAVGSIYAFSLVNQSIVDELVIIDLDAEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Appears to be the primary factor that allows S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMJ_YERE8
Sequence: MLHNIRIVLVETSHTGNMGSTARAMKTMGLTNLYLVNPLVKPDSQAIALSAGASDVIGNATIVDTLDEALAGCSLVVGTSARSRTLPWPMLEPRECGVRSAREAEHAPVALVFGRERVGLTNDELQKCHYHVAIPANPEYSSLNLAMAVQILAYEVRVAFLDRQQAAAPIVEEEEAPYPLVDDLERFYLHLEQVLSHTGFIRQAHPGQIMSKLRRLFTRARPEAQELNILRGMLTSIEKQDKYPQRGADGSEHNGKN
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB2_XANCP
Sequence: MVVDDSAVVRQVLVGVLNEAPGIEVIATAADPLLAIEKMRQQWPDVIVLDVEMPRMDGITFLRKIMSERPTPVVICSTLTEKGARVTMDALAAGAVAVVTKPRLGLKQFLTDSADELVATVRSAARANVKRLAARVTAAPLEAEVKHTADVILPAQTGRALAQTTERIVAIGTSTGGTQALEEVLTALPRVCPGIVIVQHMPEKFTAAFAARLNGLCQIAVKEAANNDRVMPGRALIAPGGKHLLLRRSGAQYFVEVLEGPPVNRHRPSVDVLFRSAARAAGSNALGIIMTGMGDDGAAGLLEMRQAGARTIAQDEHTSIVFGMPKEAIKRGGADRILPLGAMAREIVTQLQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PERE_PIG
Sequence: GDKYRXIXGRXNNVDXEKTXAQLPPXFPIKIPPNDXRI
What is the function of this protein?
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils.
What are the official names of this protein?
Eosinophil peroxidase, EPO.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
Protein: YG5N_YEAST
Sequence: MRVFRHNSMVYTRFMGIFWDCLVLDLKPLYSLDGSVTIKDGGGGYTVENDMFVCSALFPLLKGGKRKINGKKRLSHRENTLVVAKHQIGRQEEMAVKCQTKHTFTGLI
What are the official names of this protein?
Uncharacterized protein YGR269W.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECO_BACCZ
Sequence: MFQKVEGIVIRTTDYGETNKIVTIFSRELGKVSAMARGAKKPKSRLASVSQLMTHGHFLIQMGSGLGTLQQGEIISTMKEIREDIFLTAYASFIVELTDKATEDKKHNPYLFEMLYQTLHYMCEGVDPEVLSLIYQTKMLPVLGMRPYFDTCAICHQETDFVAFSVREGGFLCSRHAEQDQYRIPVGEAVHKLLRLFYHFDLHRLGNVSVKDSTKKQMRLVLNTYYDEYCGIYLKSRRFLEQLDKFQI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SAT_GEOTN
Sequence: MSLSIPHGGTLINRWNPDYPLNEVTKTIELSNAELSDLELIGTGAYSPLTGFLTKADYDAVVETMRLADGTVWSIPITLAVTEEKAKELAIGDKAKLVYGGDVYGVIEIADIYRPDKTKEATLVYKTDELAHPGVRKLFEKPDVYVGGEITLVKRTDKGQFAAFYFDPTETRKRFAELGWNTVVGFQTRNPVHRAHEYIQKCALEIVDGLFLNPLVGETKADDIPADIRMESYQVLLENYYPKDRVFLGVFQAAMRYAGPREAIFHAMVRKNFGCTHFIVGRDHAGVGNYYGTYDAQKIFSNFTAEELGITPLFFEHSFYCTKCEGMASTKTCPHDAEHHVVLSGTKVREMLRNGQVPPSTFSRPEVAAVLIKGLQKREAVTPSAR
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: ENGB_SALSV
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDCGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVVDGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIQWAVESNIQVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVEAFSSLKKQGVDKLRQKLDSWFSELAPVEEIQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: FEN1_LACTC
Sequence: MGIKGLNAIISEHVPSAVRKSEIKNFFGRKVAIDASMSLYQFLIAVRQQDGVQLASESGETTSHLMGIFYRTLRMIDNGIKPCYVFDGKPPVLKSHELSKRSARRATTEEKLKEAVEEAEKLKHERRLVKVTPEHNEEAKKLLRLMGLPYVEAPCEAEAQCAELAKAGKVYAAASEDMDTLCYRTPFLLRHLTFSEAKKEPIHEINTEILLQGLELSIEQFIDLGIMLGCDYCDSIRGVGPVTALKLIKEHKTLENIVEYIESGQANNKWKVPENWPFKEARQLFLDPDVVKGSEVDLKWSEPQEQELVDFMCKEKGFNEERIRSGIKRLQKGLKTGVQGRLDGFFKVKPKNKEQLAAANAKAKSTKAGKQATKGKVGKPGRPRK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: DLRB1_RAT
Sequence: MAEVEETLKRLQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFLRIRSKKNEIMVAPDKDYFLIVIQNPTE
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
What are the official names of this protein?
Dynein light chain roadblock-type 1, Bithoraxoid-like protein, BLP, robl/LC7-like protein, Dynein light chain 2A, cytoplasmic, Dynein-associated protein Km23.
What is the protein family that this protein belongs to?
Belongs to the GAMAD family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CS012_XENTR
Sequence: MPVQVDDIIKLLCHVSDHQKMKATIKHSARGALVAAAGAFLGGLVGGPPGIAVGGAVGGAMGAWMTSGQFKPIPQIIMELPPVQQQRLCDDIYTIVRTLDWTDATQLIMLVMGNDSLKQKVVAALINYMTKELQAEIQYGD
What are the official names of this protein?
Protein C19orf12 homolog.
What is the protein family that this protein belongs to?
Belongs to the C19orf12 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In response to oxidative stress, relocates to the cytosol forming aggregates that partially co-localize with mitochondria.
Protein: CHST9_MOUSE
Sequence: MKAKQVFFSVLLFGTAGLLLFMYLQAWIEEHHTGKIEKKRDQKGVSVTTGKIQKQITNQNSEVHMPEDLKKKGGDLLNLGSPTRVLRKISHSQRENGAYRSTEAHQGAKIEVFQKPIQMDWPLVTQPLNKSLVQGNKWKKADATQEKRRSFLHEFCKKYGRVNDPKFNLFHIVSRIYVEDKHKILYCEVPKAGCSNWKRILMVLNGLASSAYNISHDTVHYGKHLKTLDSFDLKGVHMRLNTYTKAVFVRDPMERLVSAFRDKFEHPNSYYHPVFGKAIIKKYRPNASAEALNNGSGVKFKEFAYYLLDAHRPVGMDIHWERVSKLCYPCLINYDFVGKFETLGEDANYFLQLIGAPKELTFPNFKDRHSSDERTNAHVVRQYLKDLSTAERQLIYDFYHLDYLMFNYTTPHL
What is the function of this protein?
Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans.  Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures.  Has a higher activity toward carbonic anhydrase VI than toward lutropin.  Only active against terminal GalNAcbeta1,GalNAcbeta.
What are the official names of this protein?
Carbohydrate sulfotransferase 9, GalNAc-4-O-sulfotransferase 2, GalNAc-4-ST2, GalNAc4ST-2, N-acetylgalactosamine-4-O-sulfotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PDXAL_NOVAR
Sequence: MSTASERVRPVVGTMIGDPAGIGPEVAVRALADGAVHTDSIPVLVGSAAAVERALDFTGTKARLRVMRGFEKPSDDPAIIDVIDTGALPDGVLPLGEDTEAAGHATAQWLDELDALARDGSFAATIMGPISTGSLKLAKKLDRVISPTPGESYLVLLTGPLRVAHLTDHMSLRQVIDVISADLVATAVGQLHEAMQSWGIAQPRIAVAGLNPHAMGDEDRLEIAPGIEAARARGIDVEGPIAPDSVFRHCIEGRYDMVLAMFHDQGHIAVKTWGFSGNSVIIMGPPYLHMSVAHGTAYDIVGTGKADAAMMLSAMRTCGRLASGRGFEQA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
Putative 4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_CRYNB
Sequence: MTATIDDQEKNQRSNPDHEEYQYLDLIRRIINVGEVRPDRTGTGTVALFAPPSFRFSLADNTLPLLTTKRVFLRGVIAELLWFVSGCTDAKMLSSQGVGIWDGNGSKEFLEKVGLGHRREGDLGPVYGFQWRHFGAEYTDADGDYKGKGVDQLQRVIDTIKNNPTDRRIILSAWNPKDLPLMALPPCHMFCQFFVSLPPADSPGSKPKLSCLMYQRSCDLGLGVPFNIASYALLTHMIALITDTEPHEFILQMGDAHVYRDHVEPLKTQLEREPRDFPKLKWARSKEEIGDIDGFKVEDFVVEGYKPWGKIDMKMSA
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: Y2665_BACC4
Sequence: MNKLSTKLVVAIGIGAALYGILGLWGFSIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTVTDTIAGWGIWWGWVISSGIIGFSMGLIQKRVGFSVKNGSFNKGDISYLAITGLVGIVIAIIFAGAFDIIVMGEPFDKIVIQVLGATISDVIVFLVLGLPLTIGLAKSNKKHTHLKIEK
What are the official names of this protein?
UPF0397 protein BCB4264_A2665.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBL4B_BOVIN
Sequence: MFLTVKLLLGRRCSLKVSGQESVAMLKKLVSERLHVPEEQQHLLFRGQLLADDKRLSDYRIGPNASISVVVRPLEKPAPEDTRLPQPLWHHLGQVLAKHFGPQDTEAMLQLLRREHEECLQRISLGDLEQLARYLLTKEPLAQPTGEREPEVLSPNKEEEKEAVQ
What are the official names of this protein?
Ubiquitin-like protein 4B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSPD1_BOVIN
Sequence: MHQQKRQPELVEGNLPVFVFPTELIFYADDQSTHKQVLTLYNPYEFALKFKVLCTTPNKYVVVDAAGAVKPQCCMDIVIRHRDVRSCHYGVIDKFRLQVSEQSQRKALGRKEVVATLLPSAKEQQKEEEEKRIKEHLTESLFFEQSFQPENRTVSSGPSLLTVFLAVVCITALMLPTLGDVESLVPLYLHLSVNQKLVAAYILGLITMAIFRT
What is the function of this protein?
Plays a role in differentiation and/or proliferation of mesenchymal stem cells.  Proposed to be involved in epithelial-to-mesenchymal transition (EMT).  However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation.
What are the official names of this protein?
Motile sperm domain-containing protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NAC72_ARATH
Sequence: MGVREKDPLAQLSLPPGFRFYPTDEELLVQYLCRKVAGYHFSLQVIGDIDLYKFDPWDLPSKALFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKIITADGRRVGIKKALVFYAGKAPKGTKTNWIMHEYRLIEHSRSHGSSKLDDWVLCRIYKKTSGSQRQAVTPVQACREEHSTNGSSSSSSSQLDDVLDSFPEIKDQSFNLPRMNSLRTILNGNFDWASLAGLNPIPELAPTNGLPSYGGYDAFRAAEGEAESGHVNRQQNSSGLTQSFGYSSSGFGVSGQTFEFRQ
What is the function of this protein?
Transcription factors that bind specifically to the 5'-CATGTG-3' motif and with bipartite regions with 5'-CGTr-3' and 5'-YACG-3' as cores (PubMed:15319476, PubMed:29659022).  Involved in the regulation of metabolic reprogramming during senescence by promoting the chloroplast protein degradation and the catabolism of lysine, phytol and free fatty acids via the induction of CV, LKR/SDH and PES1 expression (PubMed:29659022).  Triggers also the degradation of starch and the accumulation of mono- and disaccharides during senescence by enhancing the expression of AMY1, SFP1 and SWEET15 (PubMed:29659022).
What are the official names of this protein?
NAC domain-containing protein 72, ANAC072, Protein RESPONSIVE TO DESICCATION 26.
Protein: TYRPB_HAEIN
Sequence: MLKNKTFGSALIIAGTTIGAGMLAMPLTSAGMGFGYTLLLLVGLWALLVYSGLLFVEVYQTADQLDDGVATLAEKYFGVPGRIFATLSLLVLLYALSAAYITGGGSLLSGLPTAFGMEAMSLKTAIIIFTVVLGSFVVVGTKGVDGLTRVLFIGKLIAFAFVLFMMLPKVATDNLMALPLDYAFVVSAAPIFLTSFGFHVIMASVNSYLGGSVDKFRRAILIGTAIPLAAYLVWQLATHGVLSQSEFVRILQADPTLNGLVNATREITGSHFMGEVVRVFSSLALITSFLGVMLGVFEGLGDLFKRYHLPNNRFVLTIAAFLPPLVFALFYPEGFITALSYAGLLCAFYCLILPISLAWRTRIENPTLPYRVAGGNFALVLALLIGVVIMLIPFLIQWGYLPVVAG
What is the function of this protein?
Transports tyrosine across the cytoplasmic membrane.  The transport system is energized by the proton motive force.
What are the official names of this protein?
Tyrosine-specific transport system 2, Tyrosine permease 2, Tyrosine:H(+) symporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBM20_MOUSE
Sequence: MVLAVAMSQDADPSGPEQPDRDACVMPGVQGPSVPQGQQGMQPLPPPPPPQPQASLPQIIQNAAKLLDKSPFSVNNQNPLLTSPASVQLAQIQAQLTLHRLKMAQTAVTNNTAAATVLNQVLSKVAMSQPLFNQLRHPSVLGTAHGPTGVSQHAASVPSAHFPSTAIAFSPPSQTGGPGPSVSLPSQPPNAMVVHTFSGVVPQTPAQPAVILSLGKAGPTPATTGFYDYGKANSGQAYGSETEGQPGFLPASASATASGSMTYEGHYSHTGQDGQPAFSKDFYGPNAQGPHIAGGFPADQTGSMKGDVGGLLQGTNSQWERPPGFSGQNKPDITAGPSLWAPPASQPYELYDPEEPTSDRAPPAFGSRLNNSKQGFGCSCRRTKEGQAVLSVRPLQGHQLNDFRGLAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLLFSESAGLRSIRASGEGTLSASANSTAVYNPTGNEDYTSNLGTSYAAIPTRAFAQSNPVFPSASSGTSFAAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTEAAQAMVQYYQEKPAIINGEKLLIRMSTRYKELQLKKPGKNVAAIIQDIHSQRERDMLREADRYGPERPRSRSPMSRSLSPRSHSPPGPSRADWGNGRDSYAWRDEDRETVPRRENGEDKRDRLDVWAHDRKHYPRQLDKAELDERLEGGRGYREKYLKSGSPGPLHSVSGYKGREDGYHRKEPKAKLDKYPKQQPDVPGRSRRKEEARLREPRHPHPEDSGKAEDLEPKITRAPDGTKSKQSEKSKTKRADRDQEGADDKKESQLAENEAGAEEQEGMVGIQQEGTESCDPENTRTKKGQDCDSGSEPEGDNWYPTNMEELVTVDEVGEEDFIMEPDLPELEEIVPIDQKDKTLPKICTCVTATLGLDLAKDFTKQGETLGNGDAELSLKLPGQVPSTSASCPNDTDLEMPGLNLDAERKPAESETGLSLEVSNCYEKEARGEEDSDVSLAPAVQQMSSPQPADERARQSSPFLDDCKARGSPEDGSHEASPLEGKASPPTESDLQSQACRENPRYMEVKSLNVRSPEFTEAELKEPLSLPSWEPEVFSELSIPLGVEFVVPRTGFYCKLCGLFYTSEEAAKVSHCRSTVHYRNLQKYLSQLAEEGLKETEGTDSPSPERGGIGPHLERKKL
What is the function of this protein?
RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes encoding key structural proteins involved in cardiac development, such as TTN (Titin), CACNA1C, CAMK2D or PDLIM5/ENH (PubMed:22466703, PubMed:24584570, PubMed:27630136, PubMed:29650543, PubMed:29895960, PubMed:33110103, PubMed:35394688, PubMed:35041844).  Acts as a repressor of mRNA splicing: specifically binds the 5'UCUU-3' motif that is predominantly found within intronic sequences of pre-mRNAs, leading to the exclusion of specific exons in target transcripts (PubMed:32187365).  RBM20-mediated exon skipping is hormone-dependent and is essential for TTN isoform transition in both cardiac and skeletal muscles (PubMed:27630136, PubMed:29895960, PubMed:33110103, PubMed:35041844).  RBM20-mediated exon skipping of TTN provides substrates for the formation of circular RNA (circRNAs) from the TTN transcripts (By similarity).  Together with RBM24, promotes the expression of short isoforms of PDLIM5/ENH in cardiomyocytes (By similarity).
What are the official names of this protein?
RNA-binding protein 20, RNA-binding motif protein 20.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=The active form that regulates alternative splicing localizes to the nucleus (PubMed:35394688). Also localizes to cytoplasmic ribonucleoprotein granules; localization to cytoplasmic ribonucleoprotein granules plays an important regulatory role (PubMed:35394688). Subcellular localization is regulated by phosphorylation of different parts of the protein: while phosphorylation of the RS (arginine/serine-rich) region promotes nuclear localization, phosphorylation of the C-terminal disordered region promotes localization to cytoplasmic ribonucleoprotein granules (PubMed:29895960, PubMed:35394688).
Protein: CBID_DESPS
Sequence: MSKAYKRPLRSGYTTGACAAAVAKGATILLLSGEAPEKVEIPFPDGSRHSFCLSQQDGTGACMGTIKDAGDDPDVTNGALILATASWEGEDGPTCVHLTEIRLCGGDGVGQVSKRGLSIAPGEPAINPVPRQMIEAAVAEALSQHEKRKLTITISVPQGLELAEKTLNHRLGIVNGISILGTTGIVRPISASAWKATISACMDVARSAGLEQMVISTGRTSEKGAQQLLDLPEEAYAMMGDYLQFSLEEAGRKGFSTIHYAGMWAKIIKAALEVPQTHVRNGALEVEAAAQLLKKLGADEELCKKLFAANTAREMLSHLEDEGRDDLVKAVCQYAKKYAEKISEKTVHIYLINHRAEVIHYE
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: MHPA1_BURVG
Sequence: MRPAFEPAAGLGRAHPHETTPRSIDADVAIIGAGPVGLMIANILGLQGVRVVVVEKLTQIIDYPRAIGLDDEALRVFQSVGLAEALLPHTTPNHWMRFTLNGKCFASIEPRTDEFGWPRRNAFIQPLADQILYRGLERFDHVSTLLGHNVDRFAQDESGVTIDATDAHGVRTTIRAAYMVGADGGNSFVRRTLDVPFEGRTKPNQWIVIDVRNDPIGSPHVYLHCDARRPYVSAALPHGIRRFEFMVMPGETEEELSKPENMAALVRGVVDDPDKVDYIRQRVYTHNARLASVFRVKRILLAGDAAHIMPVWQGQGYNSGIRDASNLGWKLAMVVKGTARDALLDTYTMERRAHARSMIHLSEVAGDIFAPTSFVGTRVRDAFVRCFDVLPSLKRYFVEMRFKPMPRYEDGVVLLARRARSEGMLARLIASRGHGAFGRLVGLMSEKRESLLGRIVHGRDAQAGTPVGRMYIQPRVRVADGSIVRLDDAIGNRFAILSWGTDPTFGLTPEARRIWSALGGCFVLAKPDPQLGFRDDVPEDVIAIGDVDSRLRDWFARVPESVVLLRPDRFVAGMCSPQCVSECVSQLAQRLSLSVATGAQADDATFAPAAGLVGA
What is the function of this protein?
Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).
What are the official names of this protein?
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase 1, 3-HCI hydroxylase 1, 3-HPP hydroxylase 1.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: RS11_BLOPB
Sequence: MIKSSNLRARKRLKKQILDGVAHIHASFNNTIITISDKQGNTLGWATAGGSGFRGSRKSTPFAAQIAAERCAEIVQEYGVKNLEVMVKGPGPGRESAVRALNAAGFHITSITDVTPIPHNGCRPSKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYN_LISIN
Sequence: MKITINQASEFVGKEVTIGAWLANKRSSGKIAFLQLRDGTGFMQGVVVKAEVGDDMFATAKALTQETSLFVTGTINEDTRSPFGYEMAVSGVEVISESHDYPITPKEHGTEFLMDHRHLWLRSNRQHAIMKIRNEIIRASYEFFNKEGFLKIDPPILTGSAPEGTTELFHTKYFDEDAFLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLIEFWMIEPEMAFYKLEDSLQVQENYVAFLVKAVLDNCRLELDRLGRDVSHLEKMVAPFPRITYTEAIERLHELGFDDIVWGDDFGAPHETAIADSFEKPVFITHYPKAIKPFYMPEDPENDQVVLCADMIAPEGYGEIIGGSERIHDLETLQARMEDFDLDQEAYSWYLDLARYGSVPHSGFGLGLERTVAWISGTEHVRETIPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.