PharMolix/UniProtQA huggingface dataset:
Protein: COAT_RBDV
Sequence: MSKKAVPPIVKAQYELYNRKLNRAIKVSGSQKKLDASFVGFSESSNPETGKPHADMSMSAKVKRVNTWLKNFDREYWENQFASKPIPRPAKQVLKGSSSKSQQRDEGEVVFTRKDSQKSVRTVSYWVCTPEKSMKPLKYKEDENVVEVTFNDLAAQKAGDKLVSILLEINVVGGAVDDKGRVAVLEKDAAVTVDYLLGSPYEAINLVSGLNKINFRSMTDVVDSIPSLLNERKVCVFQNDDSSSFYIRKWANFLQEVSAVLPVGTGKSSTIVLT
What are the official names of this protein?
Coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: Y493_PASMU
Sequence: MKLVFSHVYDKSGNYIFPYCSPEESTIDYDSEEYVSRYITFHPNDVLEELYDESITNRFIGVDEIEALIDYENVKIGHWLYEEGCELEDYDPEETTYVVISRKELIYLLEKWDEFLAKPIIDPHYQEIIDTKEAYL
What are the official names of this protein?
UPF0275 protein PM0493.
What is the protein family that this protein belongs to?
Belongs to the UPF0275 family.
Protein: PSA_MYCMM
Sequence: MSFPYFISPEQAMRERSELARKGIARGKSVVALAFAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGESKAPELYRITYDGSIADEPHFVVMGGTTEPITTALKNTYTENADLPDALGIAVEALRAGSAENSSNDQPVLGVASLEAAILDANKPRRAFRRLTRSTLETLLQERDSKESAESEEPKESEEGKKTGKKSDADSSD
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH023_ARATH
Sequence: MTWKPKMLILSHDLISPEKYIMGEDDIVELLGKSSQVVTSSQTQTPSCDPPLILRGSGSGDGEGNGPLPQPPPPLYHQQSLFIQEDEMASWLHQPNRQDYLYSQLLYSGVASTHPQSLASLEPPPPPRAQYILAADRPTGHILAERRAENFMNISRQRGNIFLGGVEAVPSNSTLLSSATESIPATHGTESRATVTGGVSRTFAVPGLGPRGKAVAIETAGTQSWGLCKAETEPVQRQPATETDITDERKRKTREETNVENQGTEEARDSTSSKRSRAAIMHKLSERRRRQKINEMMKALQELLPRCTKTDRSSMLDDVIEYVKSLQSQIQMFSMGHVMIPPMMYAGNIQQQYMPHMAMGMNRPPAFIPFPRQAHMAEGVGPVDLFRENEETEQETMSLLLREDKRTKQKMFS
What are the official names of this protein?
Transcription factor bHLH23, Basic helix-loop-helix protein 23, AtbHLH23, bHLH 23, Transcription factor EN 107, bHLH transcription factor bHLH023.
What are the subcellular locations of this protein?
Nucleus.
Protein: IOLA3_GEOKA
Sequence: MTETKTLKNFIGGQWVASTSGKEEVVPNPATGEVLAKVPLSSREELDAAVAAAKEAFREWRKVPVPRRARILFRYQQLLVEHWDELARLVTLENGKVYEDAYGEVQRGIECVEFAAGIPTLMMGQQLPDIATDIESGMYRYPLGVVAGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFTEAGLPPGVLNIVHGAHEVVGGILEHKDIKAVSFVGSQPVAEYVYKTAAAHGKRVQALAGAKNHSIVMPDADLDMAVTNIINAAFGSAGERCMACSVVVAVGDIADELVRRLKEAADRIQIGNGLDKGVFLGPVIRESHKERTIKYIEIGEKEGALLVRDGRRDSATSGQGYFIGPTIFDHVKPGMTIWTDEIFAPVLSVVRARDLDEAIEIANRSEFANGACIYTDSAKAIRQFREEIDAGMLGVNVAVPAPMAFFPFSGYKNSFYGDLHANGRDGVEFYTRKKMVTARYQ
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 3, MSA dehydrogenase 3, Methylmalonate-semialdehyde dehydrogenase 3, MMSA dehydrogenase 3, MSDH 3.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: PMP22_HUMAN
Sequence: MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
What is the function of this protein?
Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
What are the official names of this protein?
Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y7I6_ENCCU
Sequence: MDISCYGWGNPLLFGTCPATTFRCSPGIQVIVFPFLLKGHSIVGLPTAKFSDLKRKTKRGSLGVYDGQCGVQPDDRFERLFDERMGGCIFGSIKDIRQQKQDVCELLEMVYEEDSSGTEGGWADGKVWREDYKDG
What are the official names of this protein?
UPF0329 protein ECU07_1860/ECU10_0040/ECU11_2100.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: UB12L_ARATH
Sequence: MIGLFKVKEKQREESQSNNGRGASTVKKQSAGELRLHKDISELNLPKSCKISFPNGKNDLMNFEVTIKPDEGYYLSGNFVFSFQVSNMYPHEAPKVKCKTKVYHPNIDLEGNVCLNILREDWKPVLNINTVIYGLFHLFTEPNYEDPLNHEAAAVLRDNPKTFEYNVRRAMMGGQVGQTSFPRCM
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Probable NEDD8-conjugating enzyme Ubc12-like, RUB1 carrier protein 2, RUB1-conjugating enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein: TATA_SACD2
Sequence: MGLGGISIWQLLIVLVIVLLLFGTKRLKGLGGDLGGAIKGFKKAMSDDEAAKQEAEEAEQKKVAAEEAAAAKTAEQKEKTEAK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARLY_GEOSM
Sequence: MSKDKLWGGRFTQPTDKFVEEFTASINFDKRLYHQDIRGSIAHATMLGKQGIIPIADVENIVSGLKAILEQIEAGKFDFSVSLEDIHMNIEARLSEKIGDAGKRLHTGRSRNDQVALDIRLYLRDELVEVSAYIDLLIDSIIHQAEENLGVIMPGFTHLQTAQPILFSHHMMAYHEMLKRDKARMEDCLKRTNVLPLGAGALAGTTFPIDREYVAELLDFAEVTRNSLDSVSDRDFAMEFCAASSILMVHLSRFSEELILWSTSEFKFVELSDSFCTGSSIMPQKKNPDVPELVRGKTGRVNGNLVALLTLMKSLPLAYNKDMQEDKEPLFDTIDTVKGCLKVFADMVREMKINPERMEVAAAAGFSTATDVADYLVRKGIPFRDAHEIVGKTVRYCIENEIDIPELSLAEWQLFSGRIEEDIFESITLEASVNARRATGGTALERVRAEIARAKEGR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB325_ARATH
Sequence: MMSDLPLDLVEKILSRVPATSLKRLRSTCRRWNALLKDRRFTEKHFHKAPKESRVLMLKEYRVFPISVNLKVTPPSVDFKGALGYSHSNSEQVVITEVFHCDGLLLCTTNDDRLVVWNPCLGETKWIQLKVDYRRYVSIFALGYIQNNESCRSYKILWTWYSYDYNSSPPQRGLGFEIYEFSSDSSWRVLDDVNHDSVVNHNSIIRSGVSLKGNTYMLAYDIEENSKFLLMFDFTTERLKRLCLPHFQDVGEMDLSVREEQLSVLNWSRITSKMEIWITNNFDTEATLLWKRVHLDSQCNCVRIFSSLYFDEEKKVVLYCNVKDGETSKKVVYIIGEDDGHYIEIPFVKSIKIERLQLIHTTRWYSLIFNYVPSLFQIQ
What are the official names of this protein?
Probable F-box protein At3g22720.
Protein: RNPA_CLOB8
Sequence: MIYRLKKNFEFTIVYKRGKSFANELLVMYILKNRRNKDRDFLAYSKVGISVSKKVGNSVVRSRCKRLITESFRLNYNYIVKGYDFVFIARNPLQSKSYFEVERAMRSLIKKAGLYNNEEITNTPN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MNMC_BURCH
Sequence: MPDRLVSATLALRDDGTLVSPEFGELHRGASGTLARAHRTFVAGNGLPARWQRRRTFTIVTTAFGAGAGFLAAWAAWRDDPARCERLHVVAVEPHPFSRDDLHRAVSHMVVDTTISADVDALLDAWPILVPGLHRLEFDEGRVVLTLAFGDTIDLLKKLVARADAFFLDGAAASGDGIRALAKLAGEHATFATHAKSDDVKHALGETGFTFREVDDRLVGDYAPRWRARRHEPPRALPVAARRAIVIGAGLAGCAVVERLAARGWDVTLIERHERIASEASGNPAGVFHPLMTRDDNVASRLTRGGFLHALARWRALERAGHAFSRSTHGMLHLAESADDFARMRDAFDAFGPPSDYATLLDADAARAHLNLPVAQGGLLFPHGGAVWPAGLCVAQYAAAGERVRLLASTCVARLERRDDTWHALDDTGATLADAPVVVLANAGDAARLAGLRHVTLQPVRGQLTLLPPGTTAPLPCPAIGDGYAVPLDDGTLLIGATFEPDDTDPAMRAAGHAENLDRVRHLLPGLIGALPDPATLRGRVAFRWVVGDRLPLIGPLADETQATANARALGGAQARDLPRMPGLYGAFGFGSRGLVWAALGAELIASQLEGEPWPLERELADAVDPARFLIRALRARRVGSAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_BRUMB
Sequence: MQADTPKGCFVAVVGPSGAGKDTIMDAARVALSGDMRFHFVRRIITRTQMPGTEDHDSLDEADFARAAGEGRFALHWQAHGLRYGLPKTLDDEIAGGAVVIANVSRRVLSDIRRLYTSRSVVVISARTEVLAQRLASRGRESREEIAARLAREVGFDDGSGDVVTIDNSGEVGASTKAFLHHLHEIAVKTIA
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: XYLS1_PSEPU
Sequence: MDFRLLNEKSQIFVHAEPYAVSDYVNQYVGTHSIRLPKGGRPAGRLHHRIFGGLDLCRISYGGSVRVISPGLETCYHLQIILKGHCLWRDHGQEHYFAPGELLLLNPDDQADLTYSEDCEKFIVKLPSVVLDRACSENNWHKPREGIRFAARHNLQQLDGFINLLGLVCDEAEHTKSMPRVQEHYAGIIASKLLEMLGSNVSREIFSKGNPSFERVVQFIEENLKRNISLERLAELAMMSPRSLYNLFEKHAGTTPKNYIRNRKLESIRACLNDPSANVRSITEIALDYGFLHLGRFAENYRSAFGELPSDTLRQCKKEVA
What is the function of this protein?
Regulatory protein of the TOL plasmid xyl operons.  XylS activates the xylXYZLTEGFJQKIH operon required for the degradation of toluene, m-xylene and p-xylene.
What are the official names of this protein?
XylDLEGF operon transcriptional activator 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFWD3_MOUSE
Sequence: MAEVAVGQASDLVPSEMDHEVIYSHLQGPLEGTIEPATPTEVVSNGAPLQPAPAELANSQGGAHVQPAPAEVVSSQDGLPTLQPLPPASIDLTEEVQPSEENMEVVNPGTSEEPSQGSGANPTAGAARSVSMNNFISGLQRLHNMLELLRPPPADHSVGPIRTRRRMAPILRARAGESQRQDNGRYVPHTPLYAYFQVSRSQPYPLPAAHDSETRNPPSGTDSDSDGSAEDEEVVVQAEEPEANIPEQGVIATDQEATSVTGDDAVPKESPQKPNMLSAMEDEEGETCTICLEQWTNAGDHRISALRCGHLFGFRCISKWLKGQTRKCPQCNKKAKHSDIVVIYARSLRALDTSEQERMKSDLLNEQMLRKQAELESAQCRLQLQVLIDKCTKLNSRVQDLEKFVVRHQNSAAQQCSRSKALCGKCLSSSQSPGKYSSEKTFTISQTGKCRILAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMKSSQYIPMHNKQIRGLSFSSQSKGLLLSASLDCTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYVYAGLASGSILIYDLRNTNTYIQELVPQKARCPLVSLSYLPKAAVAAFPYGGVLAGTLENASFWELKSDFSHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYKLDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENNGNVLVCTGDEASQSTLLWNAGSGLLLQNLKAGEPVLDICPFETNQNSYLATLTEKTVHMYKWE
What is the function of this protein?
E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage.  Plays a key role in RPA-mediated DNA damage signaling and repair.  Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination.  Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint.  May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome.  In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53.
What are the official names of this protein?
E3 ubiquitin-protein ligase RFWD3, RING finger and WD repeat domain-containing protein 3, RING finger protein 201.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Cytoplasm. Note=In undamaged cells, found both in the cytoplasm and in the nucleus, partially associated with PML nuclear bodies. In response to replication block, such as that caused by hydroxyurea treatment, or to DNA damage caused by ionizing radiations or doxorubicin, recruited to the nucleus, to stalled replication forks or to sites of DNA repair. This recruitment depends upon RPA2.
Protein: PYRI_SALDC
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTDEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPERINNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHYVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: OPSD_TRIMA
Sequence: MNGTEGPNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNVEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSASIYNPVIYIMMNKQFRNCMLTTICCGKNPFAEEEGATTVSKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: U499_CHAGB
Sequence: MKSSIHVVLFFLLSLVASMALPRRQAQAPFAVVDFSGKAACHSILTSCRVDTDCCAGLKCGIFDEDALCVPQG
What are the official names of this protein?
UPF0499 protein CHGG_06021.
What is the protein family that this protein belongs to?
Belongs to the UPF0499 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS3_NITEC
Sequence: MTDEWLDTINWSVDGLIPVIAQDENGGKILMVAWMNRDALKRTVETGEAVYWSRSRKKLWHKGEESGHTQIVQAIHLDCDKDVLLLSVEQKGGIACHTGRQSCFFRQLKNGEWVITEPVIKDPSQIYTQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC_ERWT9
Sequence: MEREIVSIDAGWWVVSEEHKIWLPAGELPHGDAASLGLAGSSGSRIGEWQGEAVWLIRGSRPDDMGSLRQLLDRDSALFRLAGRGIQLAEFFRSHQWCGYCGHKMHNSRTEWACLCHHCRQRYYPQIAPCIIVAIRRGAEILLAQHTRHRNGIYTVLAGFVEVGETLEQTVAREVMEESSIKVKNLRYVTSQPWPFPQSLMVAFMADYDDGEISIDRKELIDAGWYRYDALPLLPPAGTVARRLIEDTVALCRAQEENGER
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: DER_KLEP7
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEEGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKTDGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALLPWVDEVNPQEEVDEDAEYWAKFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTRDSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHGSGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRKRKRLIKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: DNAA_EHRCR
Sequence: MNDGGTGLLGDCVKEKLQSDNQVIWKDIQVKLHKFYGNAIYDSWLSVLVYINNEGGKVLLSAPTRFIKEWILVHYLDQILKYWQDEDQSVCSVDICVVNNQDTNLLVNIKDQQDKEVRNNYDHLSSPLDPRFTFDNFVVGKPNELAFAAARRVAESNEPISGSNPLFLYGGVGLGKTHLMHAIAWYIIKSSSKRKIAYLSAEKFMYQYVTALRSKDIMLFKEQFRSVDILMVDDVQFISGKDSTQEEFFHTFNALIDQNKQLVISADRSPSDLDGVEERIKSRLGWGLVADINETTFELRLGILQLKVEKMGINIPNKVLEFLAKNIKSNIRELEGALNKVVAHSSLVGCSITLDSASDILSDLLRANHKSVTLECIQRKVAEFFNIKITDMYSTRRLRTLARPRQVAMYLSKKLTQKSLPEIGKSFGGRDHATVIHAVKQIEKLIDTDSKLRDDINLLTRMLR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR1_MYCTU
Sequence: MAVDSDYVTDRAAGSRQTVTGQQPEQDLNSPREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVRHAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: TES_MOUSE
Sequence: MSATHPTRLGTRTKESNACASQGLVRKPPWANEGEGFELHFWRKICRNCNVVKKSMTVLLSNEEDRKVGRLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKFPSEMNAQGDKVHNCGNRHAPAAVASKDKSAESKKTQYSCYCCKHTTNEGEPAIYAERAGYDKLWHPACFICSTCGELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDHILAGKIYVMVTDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKRMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin, TES1/TES2.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers (By similarity). Detected at the subacrosomal layer in round spermatids.
Protein: ADAT1_XENTR
Sequence: MQAKGLWSADEIAALSYGHYTTQLPKQGLPDPSREWTLMAAVIQIESVEDTKVIKKVVAMGTGTKCIGQAKLRKTGDVLQDSHAEIIAKRSFQRYLLHQLSLAVSDTKDCLFIPGTEKGKWMLRPEISFVFFTSHTPCGDASIIPVISHEDELGHPLPSEVTEKDHSSNNVCESVNTTYKRKVRSEEDIGFISKKMKHSIDEILTRPENYEEENRHDFPSTCQKALDVHRTGAKCVAGELQDSYSPGVNYHTVGVLRIKPGRGDRTMSMSCSDKMARWNVLGCQGALLMHFLQQPIYLSAVVVGKCPFSQDAMERALYNRCHKVLSLPCAFRLNRVQIIQSDLEFQHGRHALTKKDATRKLVPCGAAVSWSAVPHHPLDVTANGYRQGTTRKAIGSPQCRSRICKAEIFNTFRELVQRLSEKQRSESLSSQGLKTYWDYKAAAITYQEAWNCLRQQAFTSWIQTPRDFLMFS
What is the function of this protein?
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
What are the official names of this protein?
tRNA-specific adenosine deaminase 1, tRNA-specific adenosine-37 deaminase.
What is the protein family that this protein belongs to?
Belongs to the ADAT1 family.
Protein: RECO_YERE8
Sequence: MEGWQRAFVLHGRPYSETSLMLDLFTEGEGRMRVLAKGARGRRSNLKGCLQPFTPLLVRWTGRGEVKTLRSAEPVSLALPLTGSMLYSGLYVNELLSRVLEHQTNYSALFFDYLHCLQSLAGSDGSPEYALRQFELAILAHLGYGVDFLHCAGSGQPVSDTMTYRYREEKGFIASLVVDHYSFTGRQLLALANREFPDADTLRAAKRFTRIALKPYLGGKPLKSRELFRQFVIKPPSEPLP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TRPB_PYRHO
Sequence: MIVFGSKAEIHAKSILKDGEIPKRWYNILPDLPEPLSPPLDPETNETINPEKLTRIFAKELIKQEFSEKRYIKIPKEVRELYAKIGRPTPLFRATNLEKILKTPARIYFKYEGATVTGSHKINTALAQAYYAKKEGIKRLVTETGAGQWGTALSLAGALIGLKVRVYMTRASYYQKPYRKILMEIYGAEVFPSPSENTEVGKRFLREDPNHPGSLGIAISEAIEDVLSDEKARYSLGSVLNHVLMHQTVIGLEAKKQVKEFEEPDVIIGCVGGGSNFAGLSYPFIKDVLDGKAEYEFIAVEPRAVPTMTKGVYTYDYGDSAGLTPKIKMYTLGHTYYVPPIHAGGLRYHGLAPTLSVLMNHGIVKPMAYHQTEVFEAAVLFAKAEGIVPAPESAHAVRAVIDKALEAKRKGEETVILFNLSGHGLLDLKGYEDYLEGKLEDYEPQILNLSMAPRPPNAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LFTR_RHIEC
Sequence: MAGPRRKSPGITPDILLRAYSIGLFPMAESADDPEIFWVEPELRGVLPLDNFHISKSLAKRVRRRPFEIRFDHDFEQVIAACAEETSGRPSTWINQTIRSLYATLFEIGHAHTVEAWDGDELVGGLYGVSLGSAFFGESMFSRRTDASKICLVHLVERLREKGFTLLDTQFTTEHLKTFGAIDVPKAEYALLLAVAMESPHLKF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_HALH5
Sequence: MIYYIVALVIILLDQWTKWLVVRHMEIGESIPLLDSVLYLTSHRNKGAAFGILEGQMWLFYIITSIVVIGIVYYMEKEAKHDRVFATALALILGGAIGNFIDRIFRGEVVDFVNTYIFTYNFPIFNVADSALCVGVGILFLKMIRDERKAKKEKNA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.