PharMolix/UniProtQA huggingface dataset:
Protein: KBTBC_HUMAN
Sequence: MECKIEGKEKYQHSLNLLNKIQNMKELAEMIDVVLTAEGEKFPCHRLVLAAFSPYFKAMFTCGLLECNQREVILYDITAESVSVLLNYMYNAALEINNANVQTVAMAAYFMQMEEVFSVCQKYMMDHMDASNCLGIYYFAKQIGAEDLSDRSKKYLYQHFAEVSLHEEILEIEVHQFLTLIKSDDLNISREESILDLVLRWVNHNKELRTVHLVELLKQVRLELVNPSFLRQALRRNTMLLCDADCVDIIQNAFKAIKTPQQHSLNLRYGMETTSLLLCIGNNSSGIRSRHRSYGDASFCYDPVSRKTYFISSPKYGEGLGTVCTGVVMENNTIIVAGEASASKLSRQKNKNVEIYRYHDRGNQFWEKLCTAEFRELYALGSIHNDLYVIGGQMKIKNQYLITNCVDKYSVERDNWKRVSPLPLQLACHAVVTVNNKLYVIGGWTPQMDLPDEEPDRLSNKLLQYDPSQDQWSVRAPMKYSKYRFSTAVVNSEIYVLGGIGCVGQDKGQVRKCLDVVEIYNPDGDFWREGPPMPSPLLSLRTNSTNAGAVDGKLYVCGGFHGADRHEVISKEILELDPWENQWNVVAINVLMHDSYDVCLVARMNPRDLIPPPSDLVEEGNEH
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 12, Kelch domain-containing protein 6.
Protein: POZ1_SCHPO
Sequence: MNEKIRSQSVLNTLETFFIKENHYDMQREESSIVNACLRYLGYSKSMCHEKMPIFMDIAFIEYCFNLSLDPSSFQNLPITQTQPDSQQILWEYSLISNALERLENIELERQNCMREDGLVKYTNELLLNKETLNNEALKLYSCAKAGICRWMAFHFLEQEPIDHINFTKFLQDWGSHNEKEMEALQRLSKHKIRKRLIYVSQHKKKMPWSKFNSVLSRYIQCTKLQLEVFCDYDFKQREIVKMLTSNIN
What is the function of this protein?
Telomeric DNA-binding protein that negatively regulates telomerase and telomere length.
What are the official names of this protein?
Protection of telomeres protein poz1, Pot1-associated protein poz1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: ABRAL_HUMAN
Sequence: MNVDHEVNLLVEEIHRLGSKNADGKLSVKFGVLFRDDKCANLFEALVGTLKAAKRRKIVTYPGELLLQGVHDDVDIILLQD
What are the official names of this protein?
Costars family protein ABRACL, ABRA C-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the costars family.
Protein: EX7S_SHIFL
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU178_SCHPO
Sequence: MKFPDLLRCSRAVSLARPDLPRNSPDVYDTKIPILQAITAKKCQRFRGDWGAKRKLPILKNRHISIQKFDTFEHQCAFISSDRFVRTLKRIYDLKLPVPLNDYEQISPYLLQKYNTFSSSNPKSRPTLPPGILYAKLKLLDSFSDSEKKRLSLVSFIQTKKVPLPFTYGKFAPDSKECLFGVSGVIAATSLKGITSTKNRYVIRSLNVDETGKTIPNITRENRSI
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 178 protein.
Protein: PPM1_LIMPO
Sequence: RRWCFRVCYRGFCYRKCR
What is the function of this protein?
Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.
What are the official names of this protein?
Polyphemusin-1, Polyphemusin I.
What is the protein family that this protein belongs to?
Belongs to the tachyplesin/polyphemusin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_STRVN
Sequence: MPPKKKKVTGLIKLQIQAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGWVIPVEITVYEDRSFTFITKTPPAAKMILKAAGVEKGSGEPHKTKVAKITRDQVREIATTKMPDLNANDLDQAEKIIAGTARSMGVTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UREF_HAEI8
Sequence: MAQTLNRSLTDLGALLHLVDPTLPIGGFNHSNGLETFVQQRVVESKATLEEYVQTQLLQNWIYNDGAYLSLAFDAMCEGNFDRLCELDWQLSATKVARESREGSFKLGVRLLKIFIRYETHTLLTAYQQAIAEKRVQGYFPIVFAMVAQAMGLSKADTLYAFYYNAAVGAITNGVKLIPLSQMDGQDILFDLRGSLVQAVELSFDPDEEWLGAATLANDIRAMQHEVLYTRLYMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PROM3
Sequence: MMSSPIPHQQTIAAVATAVAPGQGGIAVVRLSGPAAEVVGRSVVSIPGQQLWVSHRVLYGHVMDESGKERIDEVLVLLMKGPRSFTGEDVVEIHCHGGLMAVQRVLERVLAQPHVRRALPGEFSQRAVLNGRLDLTQAEAISELVAARSRRAAQLAMTGVDGGIQRRITSLRERLLDQLSELEARVDFEEDLPPLDAAELLLELQCVRRELEQLVEDAKRGDVLRQGLQVALVGRPNVGKSSLLNRLSRRERAIVTDLPGTTRDVLESEIVLEGVPITLVDTAGIRATKDALEQLGIDRSHQALAAADVAVLVFDLSLGWTADDAALLAQIPDDLPRLLVGNKADLQPASMTASLSNEVDGKTVDVMLSALTGQGEEALIEAVLKTCGASEAQGLVVALNQRQQDLAATAAIALARTQEAAAQKLPWDFWTIDLRQAISSLGEITGEEITEAVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_PELPD
Sequence: MLLVIDVGNSNIVLGICDGTQLVRNWRISTDKSRTSDEYGVLLHSLFASAGLGFDTVDAAIISSVVPPLTGVMEAICRDFFHLTPFVVGPGIKTGMPILYDNPREVGADRIVNAVAGYEKHKCSLVIVDFGTATTFDYVNARGEYCGGAIAPGLAISLEALFQRASKLPRVDIARPPQIIARNTVNSMQAGIFYGYVGLVDEIVNRIVAESKDTPRVIATGGLAKLIAPESRTIVEVDDFLTLDGLKILYERNR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2669_MYCBO
Sequence: MINPTRARRMRYRLAAMAGMPEGKLILLNGGSSAGKTSLALAFQDLAAECWMHIGIDLFWFALPPEQLDLARVRPEYYTWDSAVEADGLEWFTVHPGPILDLAMHSRYRAIRAYLDNGMNVIADDVIWTREWLVDALRVFEGCRVWMVGVHVSDEEGARRELERGDRHPGWNRGSARAAHADAEYDFELDTTATPVHELARELHESYQACPYPMAFNRLRKRFLS
What are the official names of this protein?
Putative O-phosphotransferase Mb2669.
What is the protein family that this protein belongs to?
To S.violaceus chloramphenicol 3-O phosphotransferase.
Protein: ISPG_CHRVO
Sequence: MDSVNIARRPTRLVRVGHVLVGSDAPVMVQSMTNTDTADAAGTAEQVYQLAQAGSEVVRITVNSPEAAARVAEIRQRLDDLGCDVPLVGDFHFNGDRLLKEFPDCARALAKYRINPGNVGKGAKGDDKFAFMIRTAMEHDKAVRIGVNWGSLDQALLARMMDANNRAANPLPLPKLMQEALIVSALESAEKAVEIGLSPDNIILSCKVSNVQDLISVYRELGGRCDYPLHLGLTEAGMGSKGIVASSAALAVLLQEGIGDTIRISLTPQPGEARTKEVVVAQELLQTMGLRSFTPLVTACPGCGRTTSTFFQELADHIQSYLRERMPVWRLQYPGVEDMKVAVMGCVVNGPGESKLADIGISLPGTGEVPVAPVYVDGQKDVTLKGDNIPAEFTAIVDNYVKTRYGEGGAKRREVASRTIPIRPVKA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: AQP5_GIBZE
Sequence: MSSSILNNRSARSTPAGANPAFNPPAEASSSSTQSGVPYIRENSPEAESIPSNPAMTPIITHGDSLASPGGRNSEADTVVPLQPAVSQDAIRSRPGSRTGNFVTPKAARFSQDGAEPIMQYSSGSVKSARRRTREREDYDFDQAADYAPMSEYERYYRNEGRNDRDRYTRRGPYPPPTFMNRRRAPPLDSDEEFYSSDDPRIPPNDRRRMMDEEAGYPGRPHAFRRTSTLNGFNITTGKLQWNELSRQEKSEIMRLPLTQWMNSNFKNHFVAGVGEFIGTTMFLFFAFAGTEVANIQADTTNRTTTGESTGSLNVSKLLYISIIFGFSLMVNVWVFFRISGGLFNPAVTMAMLMVKAISVTRAIVLFLAQILGSMLASVVVRYLFPETFNVRTTLGGGASLVQGVFIEALLTAELVFTIFMLAKEKHRATFIAPVGIGLALFIAEMVGVQFTGGSLNPARSFGPCVITGSFDTEHWIYWVGPAIGSLIAVCFYWFIKTLEYEMANPGADGDDLNDPTKNPEKRAEIQASKPVPTAAFGSGKTASILS
What is the function of this protein?
Probable water channel that may have redundant functions with FgAQP3.
What are the official names of this protein?
Probable aquaporin-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: TRAP_TGMVY
Sequence: MRNSSSSTPPSIKAQHRAAKRRAIRRRRIDLNCGCSIYIHIDCRNNGFTHRGTYHCASSREWRLYLGDNKSPLFQDNQRRGSPLHQHQDIPLTNQVQPQPEESIGSPQGISQLPSMDDIDDSFWENLFK
What is the function of this protein?
Strong activator of the late viral genes promoters.  Enhances the expression of the capsid protein and nuclear shuttle protein.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  Suppresses the host RNA silencing by inhibiting adenosine kinase (ADK), a kinase involved in a general methylation pathway.  Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense.  Determines pathogenicity.
What are the official names of this protein?
Transcriptional activator protein, TrAP, Protein AC2, Protein AL2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae transcriptional activator protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=The phosphorylated form appears to accumulate almost exclusively in the nucleus, whereas the non-phosphorylated form is found in both nucleus and cytoplasm.
Protein: PYRH_FRATT
Sequence: MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAVEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFGIPIYVFDLTQPNALVDAVLDSKYGTWVTLD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_PSEPF
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVNLAGKKVLDVGCGGGILSEAMAQRGATVTGIDMGEAPLAVAQLHQLESGVNVEYRQITAEALAEEMPEQFDVVTCLEMLEHVPDPSSVIRACFRMVKPGGQVFFSTINRNPKAYLFAIVGAEYIMKLLPRGTHDFKKFIRPSELGAWSRMAGLTVKDIIGLTYNPLTKHYKLAADVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: XYLA_SALPA
Sequence: MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHDVDVSPEGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDPEVFSCAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELGQQILKGQLSLGKLAQYAEQHHLAPVHQSGHQELLENLVNRYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIB3_MYCBO
Sequence: MPQPEQLPGPNADIWNWQLQGLCRGMDSSMFFHPDGERGRARTQREQRAKEMCRRCPVIEACRSHALEVGEPYGVWGGLSESERDLLLKGTMGRTRGIRRTA
What is the function of this protein?
A redox-sensitive transcriptional regulator.  Maintains intracellular redox homeostasis by regulating catabolic metabolism and polyketide biosynthesis.  Regulates expression of the redox buffer ergothioneine (ERG).  In concert with myothiol (MSH), another redox buffer, responds to low pH leading to acid resistance.  Senses changes in the intracellular redox state and helps mediate a metabolic switchover to preferred in vivo carbon sources (fatty acids).  The apo- but not holo-form probably binds DNA (By similarity).  Plays a role in virulence (PubMed:11880648).
What are the official names of this protein?
Redox-responsive transcriptional regulator WhiB3.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REN_SLCV
Sequence: MVMDLRTWDDITVHQAENSVFIWEVPNPLYFKMYXVEDPLYTHTRIYHIQIRFNHNLRRALNLHKAFLNFQVWTESIRASGTTYLNRFRHLVMLYLDRLGVIGLNNVIRAVSWATDRSYVNYVLENHEIKFKIY
What is the function of this protein?
Increases viral DNA accumulation.  Enhances infectivity and symptom expression (By similarity).
What are the official names of this protein?
Replication enhancer protein, REn, Protein AC3, Protein AL3.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae replication enhancer protein family.
Protein: ARAT2_THELN
Sequence: MALSDRLEMVNPSEIRKLFDLAQGIEGIISLGIGEPDFDTPEHIKEYAKEALDKGLTHYSPNIGILELREAVAEKFKKHNGIDADPKTQIMITVGTNQQILMGLATFLKDNEEVLIPSPMFVSYAPAVILAGGKPVEVPTYEENEFRLSVDELEKYVTPKTRALIINTPNNPTGAVLTKKDLEEIADFAVEHDLMILSDEVYEYFVYDGVKNYSIASLDGMFERTITMNGFSKTFAMTGWRLGFLAAPEWVVEKMVRFQMYNATCPVTFIQYAAAKALRDERSWQAVEEMRREYERRRNLVWKRLNEMGLPTVKPKGAFYIFPRIKDTGLSSKEFSELMIKEAKVVVVPGSAFGQAGEGYVRISYATAYEKLEEAMDRMEKVLKEKKLV
What is the function of this protein?
Catalyzes the transamination of phenylalanine, tyrosine and tryptophan.  Shows virtually no activity towards aspartic acid, alanine, valine or isoleucine.
What are the official names of this protein?
Aromatic-amino-acid aminotransferase 2, ARAT-II, AROAT.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: MSA2_PLAFF
Sequence: MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMANEGSNTNSVGANAPNADTIASGSQRSTNSASTSTTNNGESQTTTPTAADTIASGSQRSTNSASTSTTNNGESQTTTPTAADTPTATESISPSPPITTTESSKFWQCTNKTDGKGEESEKQNELNESTEEGPKAPQEPQTAENENPAAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLSNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, AG513, Merozoite 45 kDa surface antigen, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: NADD_BACC0
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEAEEHFSICLEELSRKGPSYTYDTMLQLTKKYPDVQFHFIIGGDMVEYLPKWYNIEALLDLVTFVGVARPGYTLHTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RNH2_ENT38
Sequence: MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLNDSKKLSEKRRLALFDEIKEKALAWSLGRAEPEEIDELNILHATMLAMQRAVAGLKIVPEYVLIDGNRCPALPMRSLAVVKGDSRVAEISAASIIAKVTRDAEMAALDLSYPQYGFAQHKGYPTAFHLEKLSEHGPTEHHRRSFGPVKRALGLVC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US8A_HHV2H
Sequence: MDPALRSYHQRLRLYTPIARGVNLAARSPPLVREARAVVTPRPPIRPSSGKASSDDADVGDELIAIADARGDPPETLPPGAGGAAPACRRPPRGGSPAAFPVALHAVDAPSQFVTWLAVRWLRGAVGLGAVLCGIAFYVTSIARGA
What are the official names of this protein?
Protein US8.5.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 US8.5 protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: DIVIB_CLOAB
Sequence: MKEENEYIVKRRKKRRRKRITIFLFLLICILVTLCLKLPYFNIKYINVEGNKIIKSDNIIENSKLKKGNNIFYLNLNKYKDNIMQDPYIKNVSIRQKLPNTIDIIVKERQAVFYINSGENYFIIDKNGVLLEIRKNISGMNLIKLDGVTLKNGKIGTEIPCDSRRLELINQITSVSIKDNNLKITDVDMSHILSLKVYFKNMCVVIGTPDDIYNKLNEAVNVIISQKLIDKKGYVDVSFKGNPVYSLQQ
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: IC1_HUMAN
Sequence: MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA
What is the function of this protein?
Activation of the C1 complex is under control of the C1-inhibitor.  It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases.  May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins.  Very efficient inhibitor of FXIIa.  Inhibits chymotrypsin and kallikrein.
What are the official names of this protein?
Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TPIS_SYNS3
Sequence: MRKPVIAGNWKMHMTCAQARAWIGTFLPLIAELPNDRHLVVAPPFTAISTLAELSEGTRLELSSQNVHWEGEGAYTAEISPSMLKEHNVQYAIVGHSEPRKYFSESDEQINHRARSAQTNGLIPIVCVGESDEQRSRGEAERVIRRQVEQGLEGLDPSQLVVAYEPIWAIGTGKTCEASEANRICGLIRSWVGSPDLIIQYGGSVKPGNIDQLMGMSDIDGVLVGGASLDPEGFGRIANYVKS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ARCFU
Sequence: MRENRGWEVFSLLTSTEVYEERVVEVPEDVQLTIEGDSFRGYTLKAVGPKGENTRYLKYRGVFIEVGDGKVRVYTTSPKKKHKAMVGTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVRVEGNEVIIENFIGEKHPRRAKIVGRAQVEISGQDIYVRGIDIEECGQTAANLEQATKIKRKDPRVFQDGIYIVKKP
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL30_DESA1
Sequence: MVKLYAILRIRGQSDTPPDVEYTLKLLRLHKKYHLVIYPAEQPGLEGMLEKVKDWVTWGEINKPTLVKLFKARGRASGGIRITDEYIAKVFAEQGIKDIEGFAEALLEGKLVLHKLENIVKPVFRLHPPRGGFDGSSKKPFNMKGELGYRGEKINELIERML
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: VIRA_AGRFC
Sequence: MNGRYSPSRQDFKTGAKPWSILALVVAAMIFALMAITSWQDNETNRAILTQLRAINIDSASLQRDVLRAEAGVVANYRPIISRLGALRKNLENLKRLFKQSHLVIGNDFSQLLDKLKVSVDTTDAAVAAFGAQNVLLQDSLASFTRALSILPKMSSTDQTVENSNELGSLMLRFVRQPSPALSLEISHELDMLQKASGGAEVPIRILAREGRVILSILPRVNDAVNMIQTSDTAEIAERLERKCLEAYSLQSVREQRARIFLGSVSVGLCIYIISLVYRLRRKTAWLTRRLDYEEVIKEIGVCFEGGGATASSLNSSAQAALGIIQRFFNAESCALALVDHGDRWAVESFAAKLPEPVWEDLALREMVSLARADERASVFRIMSTRKVSCLPPETPGVSMLLAHKSTDQLIAICSLGYQGYRLKSCPGEVQLLELATACLCHYIDVRRKQTECDILERRLEHAERLQAVGTLAGGIAHEFNNILGAILGYAEMAQNMLRRSSVTRRHIDQIISSGDRARLIIDQILTLSRKLERVTKPFSVSELVMEIAPLLRVALQRNIELKFKFDDKKSVVEGSPLEVQQMLMNLCKNASQAFTADGQIDIIVSRIFVSRQKVLAHGVMPAGDYVLLSVSDDGEGIAETVLPHIFEPFFTTRSCSGGTGLGLAAVHGHVSALAGYIDVTSAVGRGTRFDIYLPPSSKKPVSPDAFFGPCKTPRGNGEIVALIEPDPVLREVYEDKIAALGYEPVGFKTCADLCNWISKGKQADLVLVDQSSLPENQSATALHAAFKTASIIIGGSDLKMSLSSDDMTSALFLPKPISSRTMAYAIRTKIKA
What is the function of this protein?
Activates VirG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone.
What are the official names of this protein?
Wide host range VirA protein, WHR VirA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EX7S_HAEDU
Sequence: MAKKPTQNFETTLQELESIVNHLEAGDLPLEQALTEFETAIKLVQQGQQRLQQAEQRIQILLNKDEQAELADYE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_METS5
Sequence: MVSVEELMGQVIDSEMEVISKELSKALEEALNLVKQKRDSVERTYTAKMQEMVTKAKEEIEGERARLDIEVKRAVLGEKNYWLNKVYEGTIKSLGTVKNSQGYKQGLESVLKRELRDGSIVYCSEDEVDQVQKMIKGLKAKAEVRSDPKIMGGVKIQYSDVGLVRDYSLNLILDQVFESLKPKIAEILFGEM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PK21A_RUEPO
Sequence: MTHESDDPSLDWLEAELEDSLDEDFEIEFSEPMLSMEIRRIYKDQRPDLLDRQVYFRNLLRLQAELIKLQDWVQHTNSKVLIIMEGRDAAGKGGVIKRITQRLNPRIARVVALPAPSRREQSQWYFQRYVPYLPSGGEMVLFDRSWYNRAGVERVMGFATEDQVEQFFQDVPEFERMLVRSGIILLKYWFSITDEEQQLRFLMRVHDPMKQWKLSPMDLESRIRWEQYTKAKEQMFSRTNIPEAPWYIVEGNDKKRERLNCIEHLLSKIPYEDIPHEKVTLPDRRYNPDYERQVLPDELYVPKVY
What is the function of this protein?
Uses inorganic polyphosphate (polyP) as a donor to convert NDP to NTP.  PolyP hydrolysis is slightly faster with GDP, but it can also use ADP, CDP and UDP.
What are the official names of this protein?
NDP-polyphosphate phosphotransferase 1, Polyphosphate kinase PPK2 1, RpPPK2-1.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
Protein: TSAD_CLOBJ
Sequence: MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKADVAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYIKGRSTSLDINAVPNLKLGER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.