PharMolix/UniProtQA huggingface dataset:
Protein: FLAA_AQUAE
Sequence: MATRINYNYEAAVTYTSLKQNERLMNKSLLRLSTGLRILSAADDASGLFIADQLALVSAGLEQGNRNIQFGISALQIAEGGVSQIYDKLKTMYQKAVSAANDINDPNARAALQRDIENLRDAILKIAQDTEYNGIRLLNGSFNNVRIHYGARSAQTLSVSISSVLPQQLGGYVAEDSPATATDTNNVLTNIGTTNTNYSVASGDSLAFTFTDGTSITFNSLNQLGYDFNNTGTYILDASAIVNTINNNPTLQGKGIRAYAENVSEADLTFDTTNVNIDQGDEVTITFYSGGELVFTKTYTDTVTLDQFIADINNQAGGKLIASKDPSGTKLVLSTPNGETISVEVTVNDADGDTVVSSINLGALLQGAAGTVVNTSGATASAVKVGTLIVMGSENFTVQGTGIAYFTAATSGTFNSLNDVDVTTNKGAEIAQVLIQRAVRQVDTIRTQIGSTINNLQAIYDAQAVAKDNTDNAESIIRNVDFAKEMTEFTKYQIRMQSGVAMLAQANALPQLVLQLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: ERA_ECO55
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RK32_HELSJ
Sequence: MAVPKKRHSKRICKIKFYSWKSKFLKKVQFIINQKSIIKNK
What are the official names of this protein?
50S ribosomal protein L32, plastid.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid.
Protein: WDR7_RAT
Sequence: MAGNSLVLPIVLWGRKAPTHCISSILLTDDGGTIVTGCHDGQICLWDLSEELEVNPRALLFGHTAAITCLSKACASGDKQYTVSASANGEMCLWDVNDGRCIEFTKLACTHTGIQFYQFSVGNQREGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDWISSMSIIRSHRTQEDTVVALSVTGILKVWIVTSEISGLQDTEPIFEEESKPIYCQNCQSLSFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSEDGQTWTGGDFVSADKVIIWTENGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHSLLDQKDRELVICPPVTRFFYGCKEYLHKLLIQGDSSGRLSIWNIADIADKQEANEGLKTTTCISLQDAFDKLKPCPAGIIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIIIVPATQTAIVQLLQGEHMLRRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIFCVHGGEITQLLVPPENCSARVQHCVCSVASDHSVGLLSLREKKCIMLASRHLFPIQVIKWRPSDDYLVVGCTDGSVCVWQMDTGALDRCAMGITAVEILNACDEAVPAAVDSLSHPAVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTNLTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAAVLFQQVKETIKENIKEHLLDEEEDEEEVMRQRREESDPEYRASKSKPLTLLEYNLTMDTAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYNQAAGKLLQAKAEAGRKGPATESVGKGTYTVSRAVTTQHLLSIISLANTLMSMTNATFIGDHMKKGPTRPPRPGTPDLSKARDSPPASSNIVQGQIKQAAAPVSARSAADHSGSASASPALRTCFLVNEGWSQLAAMHCVMLPDLLGLGKFRPPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKETIDTWAPYLPQYMDHVISPGVTAEAMQTMAAAPDASGPEAKVQEEEHDLVDDDITTGCLSSVPQMKKMSTSYEERRKQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSNYSLARHTCKALTFLLLQPPSPKLPPHSTIRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLANITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQSIHTTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAICRFYMVSYYERSHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVSFAPDGRYLATYSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALRLARLIWTSNRNVILMAHDGKEHRFMV
What are the official names of this protein?
WD repeat-containing protein 7, TGF-beta resistance-associated protein TRAG.
Protein: LPTD_METCA
Sequence: MEGPPTAAHAAAPLRTAVFLALAASWQQPAVAVGNWNCARSTDDKQWECVAKRKDGGADTPAAPGPKAPPTALGEAALSQSNRAAPSTAVSPPTGAAPVAGTGLRPPPPVPSAASPSPSTMAGGPTEDEEDEESESAESEKAESTAAPQVAEGGSAGEPGGTPPARAPRPETPLAASRFVPSGTVSVRKEAASPQSVAAHAPGAPAGWTCKPQKESRSWDCNLVGPDPRGVARPVGAAGEPPEDWAQAATITEYDEQRFDRLLGMMPSNPWAGTCARGKRESDAAKDFLLTSKDRLARKRAPVEVHGNYGEMDDQEVATFTGDAEVTRYDQHVKGDFLSLNTEADTVNARGSVFYREKGLAFASDTAFMRMEEDKGVLRNSQFIVETMPSRGVARVAHMDSDTHSHYETATYTTCPPGNTDWMLHADEVTIDKETGRGDASHAWMEFKGVPIFYTPYMDFPVDDRRQSGFLSPTFGQSKVNGFNLSVPYYFNLAPDYDLTLQAREMTSRGPLFGGDFRWLTEHQRIRLLGEVIPEDSQTKTTRGQAGFDAMGRWTDSLFTLVDLNYVSDSKYLNQLNNTLGLVSNTFVQSQAYADYTYSNGSVRLLGDYYQNIDPSIPTEQTPYYRLPSLRGNYNEQIGDSGFRFQANAEVVNFGHGGNNVKGQRLNIRPQISYPIQSPGSFLVPSVALQNTTYMLQNQAAGTGSSLNRVAPIFSVDSGLVFDRDFELGSASLRQTLEPRVFYTYVPKINQNDYPIFDSNYYDFTYYQLFRTNRFAGADRLADMNQVTLGLTSRFIDRDTGWERLTASLGKVFFITDPSVTLVNPYGANPLGVVLGPDQGQFVYGNYNKSYANVIGKVDTRLTEAFFLGGEAQLSPYTGRFERGSVGLQYNDRQNNLMNLSYRYREPLPNQPAIEQAATIGQNTTALNNTDISFRIPFLKDWHVIGRWQYSLLYNRTLESLVGLEHETCCWRFTVLGREYLNGVNQSNAPTTNTAIFVQMELKGLTRLGDQVDRFLYRAINGYRMPNEDF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HIS7_CAMHC
Sequence: MIKKYRKTKETEISVELEICGSGNAEIDTGIGFFDHMLESFTKHSLIDLKLICKGDLNVDFHHSVEDCGIVLGSALREAIYPIKKIERFGDSVVVMDEAAFSCALDLSNRAFLVFEGPKVGKVGEFDIELLEEFFRAVAFNAGITLHLIKLRGQNLHHLSEAAFKSFAVALRRALSKNERAEIPSTKGIL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_ACHLI
Sequence: MSPNSTLWQTILQDLEKLYNEETYNELFLPVTSTFKDQNGLLTMVVANEFLKNRINKLYIAKINELATKYSSTPVRLKFVSQEEVIEEPVADRKLTIDYRQGNLNSTYTFDSFVVGKSNMFAFRMAMKVADQPGAVANPFYIFGDVGLGKTHLMQAIGNYILDNDVEKRILYVKADNFIEDFVSLLSRNKNKTEEFNAKYKDIDVILVDDIQIMANASKTQMEFFKLFDYLYLNNKQIVITSDKPASQLTNIMPRLTTRFEAGLSVDIQIPELEHRISILKRKTATLDANLEVSEDILTFIASQFAANIREMEGALIRLISYAQTFNLEITMNVVEEALGAVLKTKKKTNDLNENNYDKIQSIVADYFQVSLPDLIGKKRHAKFTLPRHIAMYLIKLKYNIPYKTIGSLFNDRDHSTVLSACEKVERDMRMDSNLKFAVDSIVKKIDSPLLK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_STREM
Sequence: MTPQAFYLALEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAITEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDSLNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELTIPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKKKETPNKYPRKAGIPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA1_MYCTU
Sequence: MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDPDVDARHVLEADAAVRLGPAPARESYLDIGKVLDAAARTGAQAIHPGYGFLAENADFAAACERARVVFLGPPARAIEVMGDKIAAKNAVAAFDVPVVPGVARAGLTDDALVTAAAEVGYPVLIKPSAGGGGKGMRLVQDPARLPEALVSARREAMSSFGDDTLFLERFVLRPRHIEVQVLADAHGNVVHLGERECSLQRRHQKVIEEAPSPLLDPQTRERIGVAACNTARCVDYVGAGTVEFIVSAQRPDEFFFMEMNTRLQVEHPVTEAITGLDLVEWQLRVGAGEKLGFAQNDIELRGHAIEARVYAEDPAREFLPTGGRVLAVFEPAGPGVRVDSSLLGGTVVGSDYDPLLTKVIAHGADREEALDRLDQALARTAVLGVQTNVEFLRFLLADERVRVGDLDTAVLDERSADFTARPAPDDVLAAGGLYRQWALARRAQGDLWAAPSGWRGGGHMAPVRTAMRTPLRSETVSVWGPPESAQVQVGDGEIDCASVQVTREQMSVTISGLRRDYRWAEADRHLWIADERGTWHLREAEEHKIHRAVGARPAEVVSPMPGSVIAVQVESGSQISAGDVVVVVEAMKMEHSLEAPVSGRVQVLVSVGDQVKVEQVLARIKD
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, resulting in the formation of carboxyl biotin (PubMed:25695631).  When associated with the beta1 subunit AccD1, is involved in branched amino-acid catabolism with methylcrotonyl coenzyme A as the substrate (PubMed:25695631).
What are the official names of this protein?
Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit.
Protein: TRPA_XYLF2
Sequence: MHRIDETFRRLRAQSRKALIPFITAGDPSLEAAVPVMHALVRAGADVIELGVPFSDPMADGPVIQHSSERALQRGVGLAYVLQTVDVFRQSDAVTPVVLMGYLNPLEIYGIARFTQQALASGVDGVLLVDLPPEEADEIRAIFSAAGLALIVLASPTTSASRLATLSGVAQGYLYYVSFAGVTGADRLDAQSAGDRLRGLRAQTQVPVVVGFGIRDAASAVVMAVDADGVVVGSALVTALSDAPDVDTACRRADAFLAPLRQALDAVK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: BPT_CAMJJ
Sequence: MLEIGFCTLEDQCPYLKDKRSRIEYKYIENCSKEINNELIKRGWRRFGRYFSRPICKDCDECLSLRILVNEYNFSRSERRVVNKNINTKVILRTPNLSNEHLFLYDKYHRFMEEKKNWKRYDLSFKQYYNLYVDGFMNFGYELAFYIEDKLVCVDLIDILEDGISSIYCFYDPDFSYFSLGKFSLLNEIQIAKKMNLDYIYLGYFVKKCQSLSYKADYTPNEILKGTKELFENEVLWEK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_THETH
Sequence: MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA
What is the function of this protein?
Located on the outer edge of the platform on the body of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S6, TS9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y4322_CHRVO
Sequence: MLPAKMVTTAFELPGYRVSANLGVVRGITVRSRSLVGNFFGGLQSLFGGNITIYTSLCERARSETYAEMCQHAQALGADAVIGMRYDATEVMTGLTEVLCYGTAVKLEPLAGREPNP
What are the official names of this protein?
UPF0145 protein CV_4322.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: HBS1_DROME
Sequence: MSRHRIVRTMDYNDEYDGYDDIYGHSVEDEHCISPTDAQQWLYDRARGQQSISAFISKNKDIQEEEADEDEDEDAAFAKARRDSESFQMPQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEILNEETNKSAKPAVNKMKAPAAPVLPKTVSKTVPTPPPKISLKEPRRGFEIPSPKVPSSPVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLDTVGWSQDRFTEIVTKLKSFLKLAGFKDSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIENFKIPERAIDRPLRMSVSDIYKGTGSGFCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFPQTCVFAGDQVSVTLPALDINNVTVGCIISDPQTPIPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRPICIERYADFKELGRVMLRVAGVTIAAGMVTKIR
What is the function of this protein?
Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway (By similarity).  In the presence of pix and pelo, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes (By similarity).  Together with pelo and in presence of pix, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway (By similarity).  Together with pelo, required for transposon silencing in the ovary and testis (PubMed:26124316).  Together with pelo, promotes meiosis and spermatid individualization during spermatogenesis (PubMed:30824860).
What are the official names of this protein?
Protein HBS1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI4_SULIL
Sequence: MEVKIKQVDEVKISRYIIKETMEDWYQFVESDVVIVGAGPSGLSAAYYLAKAGLKTLVFERRLSFGGGIGGGAMLFHKLIIEKPADEILREVNVRLKEVEEGVYVVDSAEFMAKLATAAIDAGAKIIHGVTVDDVIFRENPLRVAGVAVEWTATQMASLHVDPIFISAKAVVDATGHDAEVISVAARKIPELGIVIPGEKSAYSERAEELTVINTGKVAEGLYAAGMAVTEVKGLPRMGPIFGAMVLSGKAVAEEITKDLLKSEIRT
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: PDXH_MARN8
Sequence: MDIGDMRRDFESEGLDREHLNEDPVQQFQTWFEDARTAGILEPNAMSLATTGADGMPDLRTVLLKYFDSQGFVFYTNYGSRKAQELQENPRAALLFPWIGLNRQVRIQGAVEKVSKAESLRYFSSRPRGSQIGAWVSEQSQVITSRGLLEQKVAEMKRKFSSGEIPLPSFWGGYRVVPERIEFWQGRPSRLHDRFEYVREGDGWTIQRLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: T2G1_HERAU
Sequence: AWGKNQFNNAFPIALACFMFSQQIKPIYIRLEKRNTEHNYIAVDQIFQINPLDPQAFFAFEHSYHPYTELIIGKTPAIDVVISNLQNSQIINAFEIKLTAIPDNTTAILSDHLQGCEIVIRPDTIVYLALSIAKIFQQNSSVLLDILDPICARISDWEDVTSIKPMIPVFCELLYTIFDRYQSAQIPILLQPIWKTQGKLSILHENCLDLFVWSNFALAKVFLDASIKPSEKSITRPERTTVWLIKMLYDFAQNGKIDYKRTLDRITFNLKNDKAFAASGMVTRKYMNSPELHNPRIKRHLIKHIIINGGQRYLSPERRLDSAIVSTPSLFEDGL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GRCGYC-3' and cleaves after R-2.
What are the official names of this protein?
Type II restriction enzyme HgiGI, R.HgiGI, Endonuclease HgiGI, Type-2 restriction enzyme HgiGI.
Protein: TLP20_NPVOP
Sequence: MANTSSTTSDIVVRARVLIADDEGTLLEFEAENEHCLMRGAHEVRVIASPELDALHNGPYNEIALGDYTFHFNLVAANRFGAQVMLFAKRDDIKVSGAVFRLKVWNSKKRAVAPPHHEPEPVPAEEGAVADRAEPESGDAPPSPKKQKLDEREQD
What are the official names of this protein?
Telokin-like protein 20 homolog.
Protein: GUAA_CUPMC
Sequence: MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVTDEFVREFAPKGVILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDSREFGYAEVRAHGHTNLLKGIEDFATDEGHGMLKVWMSHGDKVTALPAGFKLMASTPSCPIAGMADEARGYYGVQFHPEVTHTSKGREMIERFVLEICATKADWVMRDHIAEAVEKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLDEGKMVMDMFAGRLHAKVVHIDASEQFLGHLTGVTDPEQKRKIIGREFVEVFQAEAKKLSNAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKRDYADLLRRADAIFIEELRKTIATEQDAAAGLCEANQVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVQTTDFMTAHWAHLPYSLLGRCSNRIINEVRGLNRVVYDVSGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CC191_HUMAN
Sequence: MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE
What are the official names of this protein?
Coiled-coil domain-containing protein 191.
Protein: RPOA_BRUSI
Sequence: MIQKNWQELIKPNKVDFITHGSRTHATVVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIRMEGEGPKRMVVRKEGPGVVTAGDIQTVGDVEILNPEHVICTLDEGAEIRMEFTVNTGKGYVPADRNRAEDAPIGLIPVDSLYSPVRKVSYKIENTREGQVLDYDKLTLNIETNGSVTGEDAVAYAARILQDQLSIFVNFEEPQKEAPQEQVAELAFNPALLKKVDELELSVRSANCLKTDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEIPAWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL36_DESVM
Sequence: MKVRPSVKKMCPKCKVIRRRGILRVICDNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: THRC_BACSL
Sequence: MYKGLLKQYASYLPVNEKTPDVSLMEGNTPLIPLLNISKQLGVQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGSEAIICASTGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAVAYGAEIISIEGNFDDALKAVRNIAAEEPITLVNSVNPYRIEGQKTAAFEICDQLQNAPDVLAIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKGHVIEEPETIATAIRIGNPASWSYAVEAAEQSHGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVIKHVESGKIKKGETVVAVLTGNGLKDPDIAISSNQLDIASVSNDIEQIKDHIKGVIMS
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: ECH20_MYCTU
Sequence: MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Catalyzes the hydrolytic ring D opening of (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA (HIEC-CoA) to (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) (By similarity).
What are the official names of this protein?
(7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA hydrolase, HIEC-CoA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: SFR1_MOUSE
Sequence: MAEEGNQEFTSKMENSSDSASTSPDAPQPSENPPSPPTSPAAPQTSENPPSPPTSPAVPQTRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPHSNSSGKQPLSGTPKERLKKARSSSHSFCSVVKRMKVENDENNETLSEPGESSKEENCSKAQESLKNKDSEPGEKSSEEKNTCESKSSDTGSSNALPKESENAIIREKLKQEKIRLIRQVEEKEDLLRRLKLVKMYRIKNDVTELENLIKKWRKCGQRLLCELQSIMSEDEDEKLTLTELIDFYGIDDNLLHYNRSEEEFTGV
What is the function of this protein?
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (PubMed:20976249).  Acts as a transcriptional modulator for ESR1.
What are the official names of this protein?
Swi5-dependent recombination DNA repair protein 1 homolog, Meiosis protein 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFR1/MEI5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNTP_MOOTA
Sequence: MEPLGLILVAVALGTDAFSLATGLALGGFRGRQAWLFAGTVGLFHIFMPLAGLYLGLLLGRLLGKVAAIIGALVLATMGTLMLWEAYNNRRQGGSMVGQVLRVIPGRGGVLGGVMAILFMAGSVSLDALSVGFGLGAISVNVPLTVLTMGFIAATMTALGLLAGRRLGSFFGNRAELAGGLILVAIGLKMLVGV
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LLDD_SALTY
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPAALAPMSKGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KCNS3_RABIT
Sequence: MVFGEFFHRPGPDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSNDVSTDTSFEESSVFEKELEKFDQLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAVRLVAAPCQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWATISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDIDVDQCSEDPPEKCPELPYFNIRDLYAQRVHAFITSLSSVGIVVSDPDSTDASSIEDNEDVYNTASLENCTAK
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1.  Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells.
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 3, Delayed-rectifier K(+) channel alpha subunit 3, Voltage-gated potassium channel subunit Kv9.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
Protein: RNC_XANAC
Sequence: MSNRTFQRGDPIGHAFADPALLAQALRHRSAGTPHNERLEFLGDGIVNLLIAEALYHRWPKADEGALTRARAELVREGALAVIGRTLNLGERLTLGPGELKSGGHRRDSILADAVEAIVAAIYLDCGFERCRAVVLPWFEASLAALPVGKAEKDPKTRLQEWLQARQLPLPTYALISESGDEHAKQFHVACILEQPVARAEGQGTSRRLAEQQAATLVIAQLDSNT
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.