PharMolix/UniProtQA huggingface dataset:
Protein: OGA_CLOPE
Sequence: MKRKMLKRLLTSAFACMFIANGLITTTVRAVGPKTGEENQVLVPNLNPTPENLEVVGDGFKITSSINLVGEEEADENAVNALREFLTANNIEINSENDPNSTTLIIGEVDDDIPELDEALNGTTAENLKEEGYALVSNDGKIAIEGKDGDGTFYGVQTFKQLVKESNIPEVNITDYPTVSARGIVEGFYGTPWTHKDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPENEMQRMQELIDASAENKVDFVFGISPGIDIRFDGEAGEEDFNHLIAKAESLYDMGVRSFAIYWDDIQDKSAAKHAQVLNRFNEEFVKAKGDVKPLITVPTEYDTGAMVSNGQPRTYTRIFAETVDPSIEVMWTGPGVVTNEIPLSDAQLISGIYNRNMAVWWNYPVTDYFKGKLALGPMHGLDKGLNQYVDFFTVNPMEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDMLYGDLAEDMKVFANHSTRMDNKTWAKSGREDAPELRAKMDELWNKLSSKEDASALIEELYGEFARMEEACNNLKANLPEVALEECSRQLDELITLAQGDKASLDMIVAQLNEDTEAYESAKEIAQNKLNTALSSFAVISEKVAQSFIQEALSFDLTLINPRTVKITASSEETSGENAPASFASDGDMNTFWHSKWSSPAHEGPHHLTLELDNVYEINKVKYAPRQDSKNGRITGYKVSVSLDGENFTEVKTGTLEDNAAIKFIEFDSVDAKYVRLDVTDSVSDQANGRGKFATAAEVNVHGKLKEAAEVTGSVSLEALEEVQVGENIEVGVGIDELVNAEAFAYDFTLNYDENAFEYVEAISDDGVFVNAKKIEDGKVRVLVSSLTGEPLPAKEVLAKVVLRAEAKTEGSNLSVTNSSVGDGEGLVHEIAGTEKTVNIIEGTSPEIVVNPVRDFKASEINKKNVTVTWTEPETTEGLEGYILYKDGKKVAEIGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRTAR
What is the function of this protein?
Binds carbohydrates.  Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.  Can bind and deglycosylate O-glycosylated peptides from mammals.  Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).
What are the official names of this protein?
O-GlcNAcase NagJ, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Hexosaminidase B, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 84 family.
Protein: MYL_PENMO
Sequence: EGFQLMDRGTFDEIGR
What are the official names of this protein?
Myosin light chain.
Protein: SYN2_MOUSE
Sequence: MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPAPGPGAATASAATSAASPGPERRPPPAQAPAPQPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPSAASRKAKVLLVVDEPHTDWAKCFRGKKILGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFIDAKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDACSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITDLVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKEPDSSKTPPQRPPPQGGPGQPQGMQPPGKVLPPRRLPSGPSLPSSSSSSSSSSSSSSAPQRPGGPTTTHGDASSSSNSLAEAQAPQAAPAQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFASLFSD
What is the function of this protein?
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release.  May play a role in noradrenaline secretion by sympathetic neurons.
What are the official names of this protein?
Synapsin-2, Synapsin II.
What is the protein family that this protein belongs to?
Belongs to the synapsin family.
What are the subcellular locations of this protein?
Synapse.
Protein: MNHC1_STAAN
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_SHESA
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEAEAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFTNEVQVIITVVSVDPQIEPDIISMIGTSAALAISGIPFSGPLGAARVGYINGEYVLNPTVTQLESSQLNLVVAGTESAVLMVESEAQALPEEVMLGSVVYGHDQQQVVIKAIAEFKAEAGKPAWNWTAPVANEALVAQVKELAEDGLAQAYQIQVKQDRYAQVAVVKAAAKEALLAANPDVDLREVDGLLGSLEKKVVRGRIIRGEPRIDGREPDMVRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPTAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGTRDGVTALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSHRDDISDHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASSNGDATREAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVTVKVMEVDRQGRVRLSIKEAQTKEAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLTT_LUPAL
Sequence: MAPQTQSLVFKVRRNPQELVTPAKPTPKEFKLLSDIDDQTSLRSLTPLVTIYRNNPSMEGKDPVEIIREALSKTLVFYYPFAGRLRNGPNGKLMVDCTGEGVIFIEADADVTLDQFGIDLHPPFPCFDQLLYDVPGSDGILDSPLLLIQVTRLKCGGFIFAVRLNHAMCDAIGMSQFMKGLAEIARGEPKPFILPVWHRELLCARNPPKVTFIHNEYQKPPHDNNNNNFILQHSSFFFGPNELDAIRRLLPYHHSKSTTSDILTAFLWRCRTLALQPENPNHEFRLLYILNARYGRCSFNPPLPEGFYGNAFVSPAAISTGEKLCNNPLEYALELMKEAKSKGTEEYVHSVADLMVIKGRPSYFYNDVGYLEVSDLTKARFRDVDFGWGKAVYGGATQGYFSSILYVSYTNSKGVEGIMALTSLPTKAMERFEKELDDLFKTKDKSQILRSHI
What is the function of this protein?
Acyl-CoA-dependent acyltransferase involved in the synthesis of lupanine alkaloids.  Can use both (-)-13alpha-hydroxymultiflorine and (+)-13alpha-hydroxylupanine as substrates.  Lower activity with (-)-3beta, 13alpha-dihydroxylupanine, but no activity with (+)-epilupinine and (-)-lupinine as substrates.  Tigloyl-CoA, benzoyl-CoA and, more slowly, acetyl-CoA, propionyl-CoA and 2-butenoyl-CoA can act as acyl donors.
What are the official names of this protein?
13-hydroxylupanine O-tigloyltransferase, (-)-13alpha-hydroxymultiflorine/(+)-13alpha-hydroxylupanine O-tigloyltransferase, HMT/HLTase, Quinolizidine alkaloid O-tigloyltransferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: CP1A1_MACFA
Sequence: MLFRISMSATEFLLASLIFCLVFWVIRASRPRVPKGLKNPPGPWGWPLIGHILTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVQQGDDFKGRPNLYSFTLISNGQSMSFGPDSGPVWAARRRLAQNGLKSFSIASDPASSSSCYLEEHVSKEAEVLISKLQEQMAGPGHFNPYRYVVISVANVICAICFGQRYDHNHQELLSLVNLSNNFGEVVGSGNPADFIPILRYLPNRSLNGFKDLNEKFHSFMQKMIKEHYKTFEKGYIRDITDSLIEHCQEKQLDENANIQLSDEKIVNVVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFITPDGAIDKVLSEKVILFGLGKRKCIGETIARWEVFLFLAILLQRVEFSVPPGVKVDMTPIYGLTMKHACCEHFQMQLRS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions.  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation.  Catalyzes the epoxidation of double bonds of certain PUFA.  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system.  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer.  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: Y807_PETMO
Sequence: MSGHNKWANIKHRKGAQDAKRSQMFTKLIRELTIAAREGGGDPESNPRLRTAVENAKAANMPKDKIESAIKKGTGELEGEELTEIMYEAYGPGGVALLISVVTDNKNRTAQEVRHVLSKWGGALAESGSVSWNFERKGLITIPKEEVEDIDELMLLAVEAGAEDLDENTDPLEIITAPENLTQVRNALKEAGYTVSEKLTFLPKTTVKLSDEDAEKLLKLLNALDDMDDVQEVFGNYEIDDEVMERLAANI
What are the official names of this protein?
Probable transcriptional regulatory protein Pmob_0807.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL14_CARMA
Sequence: YSFGL
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Carcinustatin-14.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_CAUVN
Sequence: MAEIILNVEVRDGAGTGNARATRRAGKVPGVLYGGGKAPVNIAVKANEFRKSLYTGKLLGHLVTLQYGEEKQSVIAKAVQFHPVTDEPVHFDLYRVDEHQLIKIEVPVHFKNHETSVGLKKGGTLEVIRHTVELACPADKIPEELVIDLAGHDIGDVIRISEVKLPEGVKPAMDRDFVIANVKASSAAQSDAGDTTA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ESXK_MYCTU
Sequence: MASRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMAQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxK.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: MIAB_GLUDA
Sequence: MVRRRAQEVSAVTDQPACPPAMDLAPASGSRGLHVITWGCQMNVYDSARMTDVLRPLGYHPVDTPDTADMVILNTCHIRDRAAEKVFSELGRLRLVKEARATEGQQTVLAVAGCVAQAEGKEILARAPFVDIVLGPQTYHRLPEMVARAARAAGAVIDTDFPAEQKFDFLPDAQAPQSPGGITSFLTIQEGCDKFCSFCVVPYTRGAEASRPVASVLREARRMVECGAREITLLGQNVNAYHGEGPDGRVWGLARLAEALAAIPGLARIRYTTSHPRDMDADLIAAHRDLPALMPFLHLPVQSGSDRILDAMNRGHTAADYRDLVLRLRDARPDIALSSDFIVGHPGETDADFEATLQLIRDVGFAQAFSFKYSPRPGTPAAGAPLQVAEDVKDARLQALQALLRTQQDAFNDGTVGHVVPVLFTGHGRKAGQLSGRSPYLQPVHVEGPDSLIGQIANVEIRERYTNSLSGTLVQERAFA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP3L_CAEBR
Sequence: MYHHDSGPHIEEVFDPPSRRTMMQEIETHPDVIAFGKKLRKIKNQPESTFLSSADRMEEIIDAFRDQIAKWEEEEELNEPCEYRQLKIEIFTQKKIEYQRKNNLAVDEFYKKRNLKNHSNRKPLEESRRREEPRDRVHESNIDITHRGDSTSLNHYSRHHYSQRQSQSSRFERERESDEEEENSQPIQRYRSRSPKPSYSYNQSTMQQSQRDDTNVYHRSHQSTSQPPQVRMRSGKSRVTKTHNRKFRPGQKALAEIRKYQKSTDMLIQKAPFVRLVHEIIREQTYKSQDYRIRADALMALQEAAEAFMVEMFEGSVLICNHAKRVTLMPTDIQLYRRLCLRNLS
What is the function of this protein?
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore.  Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May serve as an epigenetic mark that propagates centromere identity through replication and cell division.  Not required for chromosome segregation during meiosis.
What are the official names of this protein?
Histone H3-like centromeric protein cpar-1, CENP-A-related protein 1, Centromeric protein A related.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to chromosomes during meiotic prometaphase I and metaphase I. Upon cleavage at the onset of anaphase I, the C-terminus remains localized to chromosomes. The cleaved form transiently associates with chromosome but not centromeres during embryonic mitosis.
Protein: LCE2C_HUMAN
Sequence: MSCQQNQQQCQPPPKCPPKCTPKCPPKCPPKCPPQCPAPCFPAVSSCCGPSSGSCCGPSSGGCCSSGAGGCSLSHHRPRLFHRRRHQSPDCCESEPSGGSGCCHSSGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum.
What are the official names of this protein?
Late cornified envelope protein 2C, Late envelope protein 11.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: AATF_MOUSE
Sequence: MAAPQPLALQLEQLLNPRPREADPEADPEEATRARVIDRFDEGEEEKDDLAVSSIRKLAPVSLLDTDKRYSGKTTSRKAWKEDHWEQALPSSSDNEASDEGGSEDGDSEGLGLEEISEDVDEDLEDNKISDEGGSEDGDSEGLGLEEFSEDVEEDLEGEDEEDREEDRNSEDDGVVAAFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNGAKPNTESEEISSEDDELVGEKKKQRKAPPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHIMMDKERLLRRTQTKRSAYRVLGKPEPVPEPVAETLPGEPETLPQGPANAHLRDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTAMSDDARTELFRSLFGQLNPPDADRGK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  May function as a general inhibitor of the histone deacetylase HDAC1.  Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression.  Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression.  Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
What are the official names of this protein?
Protein AATF, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1, Traube protein.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASSY_POLNA
Sequence: MATILQNLPIGQKVGIAFSGGLDTSAALHWMKLKGAIPYAYTANLGQPDEPDYEDIPRKAMQYGAEQARLIDCRSQLAAEGLAALQAGAFHITTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPSLKIYKPWLDQLFIDELGGRAEMSEFMTQAGFGYKMSAEKAYSTDSNMLGATHEAKDLEHLSSGMKIVNPIMGVAFWKDEVEVKREEVTVRFEEGRPVALNGVEYPDLVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLFIAYERLVTGIHNEDTIEQYRDSGRRLGRLLYQGRWFDSQAIMLRETAQRWVASAITGEVTIELRRGNDYSILNTESANLTYQPERLSMEKVEGAFTPLDRIGQLTMRNLDIVDTRAKLGIYAKSGVLSLGTGGDLLNLTGKAAE
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_STRPI
Sequence: MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GRPE2_BUCAI
Sequence: MDNKENKLDEKKIFKNNKIEEKKENLIDAITVQNQKIENLKLKLLQNQKKINDIELRKLANIENIKKNTEEKIEKIKKTEIERFLKSIIPVIDSLEDILNLSTTVDIKDQPIIKGIELTLESLLNILNKLGVKIEGQKNKVFNPDIHELVSRELSKETLPNHVISVNKKGFTFNKIVLRKASVIVAEN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE 2, HSP-70 cofactor 2.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGLL5_HUMAN
Sequence: MRPKTGQVGCETPEELGPGPRQRWPLLLLGLAMVAHGLLRPMVAPQSGDPDPGASVGSSRSSLRSLWGRLLLQPSPQRADPRCWPRGFWSEPQSLCYVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
What are the official names of this protein?
Immunoglobulin lambda-like polypeptide 5, G lambda-1, Germline immunoglobulin lambda 1.
What are the subcellular locations of this protein?
Secreted.
Protein: PP12_TOBAC
Sequence: MAQNGQGIEPAVLDDIINRLLEFRNARTVRQVQLSEAEIRSLCTASKEIFLHQPNLLELEAPIKICGDIHGQYGDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNVRLWKTNTDCFNCLPVAALIDDKILCMHGGLSPDLTDLDEIRNLPRPTDIPDSGLLCDLLWSDPSREVKGWGMNDRGVSYTFGSDKVAEFLMQHDMDLVCRAHQVVEDGYEFFAERQLVTIFSAPNYCGEFDNAGAMMSVDENLMCSFQILKPTDRKPRFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1 isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: ASTD_BURM1
Sequence: MTELFIDGAWVAGSGPAFASRNPGTDDIAWQGASASAADVDRAIMSARRAFADWSALDFESRCAIAKRFAALLNERKEALAAAIGRETGKPLWEARTEVAAMAAKVGISIQAYQERTGEKRQDMADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPGVAQATVEVWKDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPEIVLALEMGGNNPLVIGEVEDIDAAVHHTIQSAFLSAGQRCTCARRIFVPQGAFGDRFLARFVDVTSKITADVFDADPQPFMGAVISARAAAKLVDAQSRLIEQGAQPIIAMKQRDPRLGFVNAAIVDVTNVANLPDEEHFGPLAQIVRYADFDEAIARANDTAFGLSAGLLADDARAWEHFRRTIRAGIVNWNRPTNGASSAAPFGGTGRSGNHRPSAYYAADYCAYPMASVESAQLTLPASLSPGLHF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: Y867_HAEIN
Sequence: MSLIKDSSIYLIGELSAKCVPFLLLPYLSRKLGVEGFGELSYYQTFLPLFVIFIGLSQDGAVARYFYVYGKRSLNLVVKTGYAYTLSIGGLGLLFCWLMQSEIMFYLVLSAIFQVFLSVQLSIRQCQKQAIPYTFIQVSSTITNAALTILMLEFYQTDLVEKRILAILISNVFVALLSYLIYRKRVNNKKFYFLQYKTAFFYIMSFGFLMIFHHGSFFIRQLDRIFIFHRFSEAELGLYAMGAQIAFILSVFILAINKALVPYLFEKLKQGSVKLKDLHRWSLLSLLIVPIPSLVTLIVPEQWLLFFLGKHFIGVKYYIIVFLLSTSLTIPYLFLVNYLFYHGKTKEISFCSVLSTMIYLGALGGLIFTDVVYIPYASVLGALGILPVLYKITKRVEENEYATH
What are the official names of this protein?
Uncharacterized membrane protein HI_0867.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family. HI_0867/HI_1700 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG11_KLULA
Sequence: MPPCKLICATSGVSHQLSNVYFPSFLDLKQFASDTFQIPLDDILLLLPYGMILKKAGWDSRKLQQEGLEEIYVFDRGIFNEEIEFSPKPRFQLFKPLPSPISDSLQLDKNVILRNLGWLKALQSDVEFFQDVIKETYQDVQRLLECGTVMLEYLKNYCYEVEVLYNGNVDFLNKLHEDGASNQWHSFYDNILGNIKVSNQLLSSFFNYSELTEIEDSIHRLDRELNAKLKELKKSIDECYQQRTQLISDLDDVKKNSVVSSDDMDNQMVERFKEMATEIELVSNQYKEEASKDASKEKFETFKSVHVPKLQTISQAMFNKASTNLDTKATVQQKLQQLYLSVAKSQMSVIMVKSVLTKDVKTNMKFLKNEELKLSQVLDLPMCYGLYLIELYREQLWTDRYSQLRQQHESSLQHLLDDEVRQRNSWYKDFQWITRFLDVDSLLPSSVYIPSISDHKQVTLSQIKDYINQLASLNLGEPTINLLKSKVSQAELTGLHLPTDYALSKDSELIIEGYKARIKKLEHLLLDAQFHQYDSWPAGILNKETAMVQMFRNSTVSTKLQQSSTFDLPSSKQQHESNKTFEEFQNLQKDISKYSELTKTLETELSTLKSQLSHMEVEKNAYRESMTNLNKELSTLLIERENFYSEMNSRSENFKKHLGSLFEQNEELVRESEESRRKSEDLNKMKEDLLVNMATQEVQAEQERASLQEEVESLKKDLNQLQISKSKTIDAEFINFNKQLEKTLYDVFQGSIFILASIGLLLSKDQDGNFQIVRVKGLRKDLDSSLADMNSSMAKSVIAQEIKSTFESIKDQIDYKPHENFITYIEKLFGNQLFETSVIRRFNDIESLAKKLRKENKNKKLLLQKSARDKITIYNFQPGDLALFLPINDQELLLNSSISSLNSSFSSIDLNSSTQSVMQRPNVVKSDIAASILNGSSASITENIPLSKANRNPALNANGRPDTFNVNTQDSAKKHVVWAIFTATNTDIKYVLRNSTSNYELLKDREWAMGRISALEKHVVGDDSKNPFKFPRNTVWYEVDAFFNLD
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for the Cvt vesicles completion (By similarity).
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: TAR1_YEAST
Sequence: MRDSPTHKEQRAQNTMSDQMPFPFNNFTYFFTLFSKFFSSFHHCTCSLSVSRQYLALDGIYHPLRAAFPNNSTLRRHFTKNRTPRHTGFSPSMTSCSKEHRQGTAPKLPSPNYNSGTEGTRFQI
What is the function of this protein?
May be involved in mtDNA stability or mitochondrial gene expression regulation at the post-transcriptional level.
What are the official names of this protein?
Protein TAR1, Transcript antisense to ribosomal RNA protein 1.
What are the subcellular locations of this protein?
Mitochondrion.