PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_SPHAL
Sequence: MTAHKPGDPTTLNRLYGRSKGKPLRAGQQDLVDTLLPQIAVPLDGEVTARRLFGFDRPLHFEIGFGGGEHMAARADMLPDHGFIGAEPFINGVAQALVHVAGDHGQHPPLGNVRIHHGDALEVLRRIPDGALAFVYLLHPDPWPKARHAKRRMMNDGPLDLIAAKLKPGGEFRFGTDHPIYLRHALMVMRRHRHQFEWLAKDARDFQVRPGGWPETRYEAKARAQGHEVWYFRWRRR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: YDZO_BACSU
Sequence: MSKKKSFNREYITSYYYIPFHRLEQGFYTSMEYRKVGVFKQQGKIDGHYVGVMAMEKILAM
What are the official names of this protein?
Uncharacterized protein YdzO.
Protein: LLDD_SALSV
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTLKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGRSLPAALAPMSKGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NAT8_RAT
Sequence: MASFHIRQFQERDYEQVVDMFSRGMKEHIPTAFRHLLLLPRTLLLLLGVPLALVLVSGSWLLAVVCIFFLLPFLWFLAGQPWKNYVSKCLHTDMADITKSYLSDRGSGFWVAESGGQIVGTVGALPVKDPPSGRKQLQLFRLSVSSQHRGQGIAKALVRTVLQFARDQGYTDVVLVTGLLQQGAVTLYYSMGFQKTGESFMDILTWLVDVSLIHFIYPLPSS
What is the function of this protein?
Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids.  This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates.  The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile.  Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins.  Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1.  May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (By similarity).
What are the official names of this protein?
N-acetyltransferase 8, Acetyltransferase 2, ATase2, Camello-like protein 4, Cysteinyl-conjugate N-acetyltransferase, CCNAT.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ASSY_SHESH
Sequence: MSNETKKTGVKKVVLAYSGGLDTSAIIPWLKETYDNCEIIAFCADVGQGDAELEGLHEKAISSGASECYIVDLKEELVADYIYPTIATGAIYEGTYLLGTSMARPIIAKAQVEVARKVGADAVCHGCTGKGNDQVRFEGCFAALAPDLKVIAPWREWEMVSREDLLDYLAERNIETTSSVTKIYSRDANAWHISHEGGELEDPWNEPTKGVWTMTVAPEDAPNEPEYVSLELEQGKITKVNGASLSPYGALTVLNEIAGAHGVGRIDITENRLVGMKSRGCYETPGGTVMFAALRAIEELVLDKSSREWREQIGAQMAHLVYDGRWFTPLCESLLAASIPLANLVSGEVVIKLYKGQAHAVKKRSENSLYSEEFATFGEDDVYNQKDAEGFIRLYSLASRIRALKAK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PROM9
Sequence: MTNSKNSSNNSTNGNELYAIAETSGQQFWFEVNRYYDIDRLNAKEKDKITLEKILLLKDKNSITIGKPYVKDAKIELEVVSHKRDKKILVYKMRPKKKTRRKMGHRQELTRVMVKSISLGKSAPKSSAKKETVKKETKPKSEKSTN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GNSA_ECOLI
Sequence: MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKMTGLESYDVKIKIM
What is the function of this protein?
Overexpression increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation.
What are the official names of this protein?
Protein GnsA.
What is the protein family that this protein belongs to?
Belongs to the gns family.
Protein: RSGA1_VIBVU
Sequence: MAKKKKLTQGQVRRVRDNQQKRLKKQADTIQWDEAMLGDSRRGLVITRFGQHADIEDAETGLIERCNLRRGIESLVSGDKVIWRKGLESMAGISGVVEAVEPRTSVLTRPDYYDGLKPVAANIDQMVIVSSVLPELSLNIIDRYLIAAETLGIEPLLVLNKIDLLQEAELATYREWLADYEKIGYKILYVSKRSGAGIAELEAQLQDRINIFVGQSGVGKSSLVNALIPELDIEEGEISELSGLGQHTTTAARLYHIPSGGNLIDSPGVREFGLWHLEPEEITKAYLEFRPYLGGCKFRDCKHADDPGCIIREAVENGEISEVRYDNYHRIIESMAENKANRQYSRNKKADL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_MESVI
Sequence: MQQNHMSLSNMIKEVKEVFFHVPALLIPTRYREIYREIDRAPKLLEQSFYTIFIKVWNITEKVTVTDVFYYSSVEDPLGLQSPRHSRWAQNTDEEQRKQARIIIQSVYKPNSFIRITSNKFTRVLITSLFVLTYFQSNGVFQSFPYFESQINGFLFKKMNNINQLEINSTNTCIIKITDLLTHQKSKELLGNSLPTNSILRWKMHSKISDIKTIFNMPEKWIYLPLGLGLENSEQIFSYRNFDICNLTKNSSNIMKIKNNRTILDPKIDKYPLVLKNKENILFFHKLPIQFFLFPYIVLRIWLAPVFVLWWSYQFNSEEKENIKNNLKNIHDIEISTIQKFVAKAITFRDIGGMESLKQELATVAFLLKQKNYSNSYPMGYLFAGPPGTGKTLMAKAMSYEAETPYLYVEGSQFRCREEGVANARVDDLFKQIQNISPCILYIDEIDSIAERREEANKQLEQLKTIGDSIEGSNINIDQKPSDTVLMQFLIYMDGYKKRNDLIIIGATNRIETLDDAIMRPGRFDRQIVFSPPFFEERKDILRIFLRNTKALVDDTTKTMMAERSIGLNGCDLRLLADNILLLSALESRNQQKTIPVINEDTFDRALERVSRIRHIISNYELAFGKYDFYRTAYHEAGIALIHTLLPECRPVYSVKLFPKPLNDRYLEIERENLKVPSSDIISTNNIDYFVQKIVGLLAGRAAESILFDFYPGQISTYLNKTYDPNIQGAYNIAHHIVEFGLLDSVTGVIHYLNSENENNIKDPFVTKINDLIQNKVTLKTNRELRKYSQAASILDFNEFWYEQDYPWQFDFIKKQYIYSNESSRNLDMEIVSILHTLFQYTYDFLKSNEQLLDHLASLVLKNKSISQKEIHLVVNSYGIKIPTKTWKAW
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2, RF2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y1242_ACTPJ
Sequence: MPSFDIVSEITMHEVRNAVENANRVLSTRYDFRGVEAVIELNEKNESIKLTTESDFQLEQLIEILIGSCVKRGIEHNSLDIPSDAEHHGKLYSKEIKLKQGIETEMAKKITKLIKDSKIKVQTQIQGEQVRVTGKSRDDLQAAIQLVKGAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein APJL_1242.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: MPIM1_PINBN
Sequence: MAMPLCSLTSYNPITTTLRGHHFLTINAYVKTQCIPCFFIKLHTRSSASKQRIIDLRSGSSNIVACVGEGATSLSSHSDIMKTGKREEIPPGVWKDDISDSIMSSHKPEADEKRVEILIAEIKSMFRGMGDGETTPSAYDTAWVAKIPALDGSDHPHFPQTLQWILQNQLQDGSWGEGTYFSAYDRLLATLACIITLTVWRTGQTQVRQGIEFFRKHAGTMEDEADNHQPIGFEFVFPAMINEAKSLCLDLPYDTPFIKQIIEKREAKLKMIPTDTLYTVPTTFLHYLEGLQEIIDCQKIIKLQSKDGSFLSSPASTAAVFMCTGNTKCLEFLNFVLIKFGNHVPCQYPLDLFERLWAVDIVERLGIDRHFKKEIKDALDYVYSHWDERGIGWARENPVAYIDVMATGIRILRLHRYNVSSDILKTFRDENGEFYRFPGQSERGVTDMLNLNRCSHVAFPGETVMEEAKLCTERYLWNALENVNPLDKWDLKENIRGEVEYALKYPWLRRLPRLETRNYIEHYGANDVWLGKMMHMMPYINDRKYLELAKLDFNNVQSIHQKELRELRRWWKSSGFAELNFLPDRVAEIFFSIASSMFEPELATCRAVYTKSTLCTVILDGFYDVHGSAEDIMLFNEAVKRWDHSLLDRMPEHIKTCFLALYNVVNEIAEEGRKRQGHDVLPYIRNLWEIQLESFTKEAEWSRAEHVPSFHEYIEAAAISSALPTLVLIGVIFTGEVLTDHILSQIDYRSKFAYLMSLTGRLANDTKTYQVERSRGEVASAIQCYMKENPELSEEEALEYIYRLMENALADFKREFLKTKDVPEYCRRLVFDNARSMQLIYMEGDGFKLSHETEIKEHVKKILFEPVA
What is the function of this protein?
Involved in defensive oleoresin formation in conifers in response to insect attack or other injury.  Involved in diterpene (C20) olefins biosynthesis.  Monofunctional enzyme lacking the DXDD motif in the class II active site relevant for the cyclization of geranylgeranyl diphosphate (GGPP).  Requires (+)-copalyl diphosphate ((+)-CPP) as substrate, but no activity with GGPP or ent-CPP.  Pimaradiene is the major products of the enzyme.
What are the official names of this protein?
Monofunctional pimaradiene synthase, PbmPIM1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
Protein: MYG_SEMEN
Sequence: MGLSDGEWQLVLNVWGKVEADIPSHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLELISESIIQVLQSKHPGDFGADAQGAMNKALELFRNDMAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1211_METMP
Sequence: MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLVVNEKSVPGPDEDTATIAVQSARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAADLEFACKAGTAGIQMCMGLVGSEMMEYAMAVGADTAQGAPGDALEYTAAAGGAAFIIGAKKEEFIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMEKMGTTSKDYDYCVFHQPNGKFYLTAAKKLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAKADDRIFVVSYGSGAGSDAFDITVTDRISEVVDKEITTEKLLEQKKYVDYAVYLKYRGKIRM
What are the official names of this protein?
UPF0219 protein MMP1211.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: RS15_THEMA
Sequence: MVSLDPEKKNEIIKEFQIHENDTGSVEVQIALLTARIKHLTEHLRKHPKDFHSRRGLMKMIGRRRKMLKYLRHKKPEVYRELIAKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SYL_LEUCK
Sequence: MPYEHQQIEQKWQKFWDDNQTFATSDTTDKPKYYAVDMFPYPSGQGLHVGHPEGYTATDIMSRFKRAKGFNVLHPMGWDAFGLPAEQYAMKTGHNPADFTSQNIDHFREQIKSLGLSYDWNREINTTDPSYYKWTQWIFEKLYEKGLAYESNMMVNWDPIDRVVLANEEVIDGKSERSGNKVERKALRQWVLKITAYADRLVDDLDDLDWPEAIKEQQRNWIGRSKGAAVFFNVDHADAKIEVYTTRPDTLFGATYMVLAPEHELVDSIVTAEQKQAVADYRAAIAAKSDLERTDLNKDKTGVFTGAYGINPINGEKLPIWIADYVLASYGTGAIMAVPAHDDRDFEFAKKFDLAIKPVIAGGENDDVAYTGDGVHINSDFLDGLDKATAIDQAIDWLEAHQAGHAQTNFRLRDWIFSRQRYWGEPIPVIHWEDGTTSLVPENELPLLLPHATELRPSGSGESPLANLTDWLEVTRDDGVKGRRETNTMPQWAGSSWYFLRYIDPHNDHQLADPEKLKYWMNVDLYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLVNQGMILGANHEKMSKSKGNVVNPDDIVREYGADTLRVYEMFMGPLTQSKPWSEEGITGSRRWLDRVWRLLIDDEGQLRDHVTTVNPGDLDKIYHQTVKKVTDDLENMRFNTAISQMMVFVNDAYKSDALPVTYMNGFIQLLAPFAPHLAEELWVRLGNRESISYVSWPTYDDTKLVDDTVEIIFQVNGKVRGKATVARDINQDDMITAAKADDNVQNFITGKTVRKVIAIPGKFVNIVVS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_BACAA
Sequence: MSIPSILRKETLKKKDKNIDLQENNINDLVVSASRVIAPLWPISTFAAHHPWMGLEKQSFEQVANWLKEARNVDIYPSASMIHSAKAKGEIEESFLQIALSRWLDSQSFHMPRETAERFCQEALKLERLPSSLLSSPELNKLAEEINYVNTGSMKDSSMQPISSLIENQNGDNLSDILNYHIIKWCKLYLDDAGASWAMPNREKGFYRAWQHLITFDPALSKTERKVLKDWPEDALIALTKALSELGISESNMQAYLEGHLLSLPGWAGMIRWRSQQSIEEQELLIEYLAVRLSMELAIVKPYLPLKNQKVEKKVSIVPLIASWIYWGDISIEKWLQMSATEQSELLAFAYRFDENTRKKLWLEAWEQTHAEQLREKIASKQRATHDKKRVVAQLAFCIDVRSEPFRRHLEKLGPFETFGIAGFFGLPIATTELGSNDSHPSLPVILKPKHQIKELTDENECKSYEQRKMVGSSVRYTFKTMKQNVLTSMLLPEVSGPLLGLQMVTRSFVPRRVGGFIRNLRKNMLQKPDTTFSLNHVHDTNCEIPIGFTKEEKVNYVRQTLKMVGLTEGFAPLVVMCGHSSQSTNNPYAAALECGACGGAAGGFNARVFATLCNLPEVREALSAEGIKIPDDTIFAAAEHKTTVDELEWIYVPELSETAQEAFDCIEAIMPNVSQHANRERLMQLPHFKTKIKNPSKEAHRFAEDWSEIRPEWGLARNASFIIGQRELTQECDLEGRAFLHNYDWKQDESGDILANIIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLPGLPWQSVMQSDRETYHSPLRLLIVIQAPTKYIERLLNNNFTFREKVQNGWVRLASVDPEGRWKNW
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BPT_PSEFS
Sequence: MTELARLKFYATQPHSCSYLPDEQATTLFLDPSQPMDVHVYADLSEMGFRRSGDHLYRPHCQNCNACVPARIPVAQFLPDRNQKRILKRNADLTVMPAKPRFTEEYFDLYQRYIEERHADGDMFPPSRDQFSTFLVRDLPFSRFYEFRADGRLVAVAVTDLLPNGLSAVYTFYEPAEERRSLGRFAILWQIGEALRQELEAVYLGYWIKNCKKMNYKTQYRPIELLINQRWVTLN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_HAEIN
Sequence: MLALLKQFSEKRFVWFLLAFSSLALESTALYFQYGMGLQPCVLCVYERLAMIGLFVAGTIALLQPRVFILRLIALALGLFSSIKGLLISFRHLDLQMNPAPWKQCEFIPNFPETLPFHQWFPFIFNPTGSCNESQWSLFGLTMVQWLVVIFSLYVVILTLLLIAQVIKTRKQRRLFN
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13A_DICDI
Sequence: MFQKKAIVIDGKGHLLGRLASVVAKSLLSGQKIVVVRCEELNISGPLSRNKLKWADFLNLTMNTNHARGHRHGRSPSKIFWRAVRGMLPHKTPRGQAALDNMKVFEGVPAPYDKVKRVVVPSALRVVKLNTTRKYTVLSRLSQEVGWKYRAVVAKLEVQRKQRSSTYYRKAALVKAYRTQALKKFSA
What are the official names of this protein?
60S ribosomal protein L13a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RUVC_BEII9
Sequence: MMPPRLRILGIDPGLRNMGWGIVELLGSNLTYVASGVVHSDGKGELAHRLKDLHVGLAGVIDAYTPHEAAIEETFVNRDPQSTLKLGQARGIALVVPALADLAVAEYAANLIKKTVTGNGHAEKQQVAMMVKILLPKSDAGSADAVDALAVAITHAQLRRNPAALKSQAMIGQGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MUTS_XANOR
Sequence: MQTTDFNTKASSPKSTAEHTPLMKQFFAAKSDYPDLLLFFRMGDFYELFYDDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLVALGESVAICEQIGDPALAKGLVERKVVRIVTPGTVTDEALLDERRDTLLMAISRSKQGYGLAWADLAGGRFLVNEVDTVDALEAEIARLEPAELLVPDEDHWPEFLRGRIGVRRRPPWLFDADSGRRQLLAFFKLHDLSGFGIDDKPSATAAAGALLGYVEETQKQRLPHLTSIATEVASEAISMNAATRRHLELDTRVDGDTRNTLLGVLDSTVTPMGGRLLRRWLHRPLRLRDVLVQRHHAVGNLIDAGADADLREAFRALGDLERILTRVALRSARPRDFSTLRDGLALLPKVRTILAPLDSPRLQTLHAELGEHDATAHLLISAVAETPPLKLSDGGVIASGYDAELDELRRLSTNADQFLIDLEQRERASSGIATLKVGYNRVHGYYIEISKGQAEKAPLHYSRRQTLTNAERYITEELKTFEDKVLSARERSLSREKLLYEGLLDTLGTELEGLKRCAGALSELDVLAGFAERAQALDWSQPELDSAPCLRIERGRHPVVEAVRDHPFEPNDLDLHSDRRMLVITGPNMGGKSTYMRQNALIVLLAHIGSYVPASRAVIGPIDRILTRIGAGDDLARGQSTFMVEMAETSYILHHATPQSLVLMDEIGRGTSTYDGLALADAVARHLAHTNRCYTLFATHYFELTALADESHDGGASGIANVHLDAVEHGERLVFMHAVKDGPANRSFGLQVAALAGLPKAAVTQARRRLVELEQRGGESHSAQMAPTALDAPQQFGLFTAPSSAAQEALQALDPDELTPKQALEALYRLKALL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TRUA_LACLS
Sequence: MTRYKATIAYDGTDFAGFQSQTNQRTVQEEIEKVLSKLNSFEPVILQGSGRTDSGVHAFGQVIHFDLNGKARDLERLRFGLDTQTPADIAVKKVELVPDDWHARYQKHEKTYEYYLENSVTRSPFHRHSKAYFRYPLNFELMQGAMAKLVGQHDFTGFTASGSSVDDKVRTIYQAEIIQLDKENFKFIFRGNGFLYKQVRNMVGTVIKIGNDRMPVSQIDKILTSKNRNFAGPTAAPEGLYLKEVKYEPINEI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DEOB_HALH5
Sequence: MDVKRFKRVFLIVMDSVGIGEAPDAKAFGDQGAHTLGHIAERMNGLHMPNMAALGLSHIRPIQGIEKVDKPKAHYGIMQEISSGKDTMTGHWEIMGLHIREPFRVFPNGFPEELLNEIRELTGREILGNKVASGTEIIKELGDEHVKTGALIVYTSADSVLQIAAHEEVVPLEELYDICKKVRALTLDPKYMVGRIIARPFIGADGNWERTSNRHDYALKPFGRTVMNELKDAGFDSIAIGKISDIYDGEGVTESIRTISNDDGMEKLVRSMDQSFTGLSFINLVDFDAKYGHRRDPIGYGQALEQFDQQLADVVEKIGEEDVLIITADHGNDPVHHGTDHTREFVPLLVYTRGIKEGKDLGLRKTFADVGATIADNFQVEAPSIGTSFLHEL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
Protein: RPOC_ACIET
Sequence: MKSLLDLFKQFTPDEHFDAIKIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDYDAKRKEYGDEFVAKMGAEGIKELLEGIDIEIEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMILEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVEAGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQLEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYHATREKINGKGEGLVFADTGEVQRALDAGEAELHAKISVRLTEWTKDKATGEFVPETKLVDTTVGRALLSEILPKGLPFSNLNKALKKKEISKLINASFRKCGLKDTVVFADKLLQNGFRLATHAGFSVAIDDMLVPPQKAEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVQKTIDRNGKEVNEESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTSNGSLMRAIVEGGEVIESLRDRILGRTAAEEVLHPETRAVLAQPGRMLDEDLIEELEAAGVDEVKVRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIIGFNATMRYVTNTKGELVVIARSGEIIIQDEHGRERERHKVPYGATLTVKADQTIKAGTILANWDPLTRPIITEYAGTVKFENVEEGLTVAKQVDEVTGLSTLVVIDPKRRGSAKVVRPQVKLVDADGKEVKIPGTDHSVTIGFQVGALIQVRDGQEVGPGEVLARIPMEGQKTRDITGGLPRVAELFEARSPKDKGMLAEMTGTISFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQVVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESTYIAGEQVERSEILNTNEALQAEGKLPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKDAMDEAERRAIADAEAAELASAGTDDAAAEIDGSADTAD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PSA2_HALVD
Sequence: MNRNDKQAYDRGTSLFSPDGRIYQVEYAREAVKRGAPVLGVRTADGVVLAALRSTPSELMEAESIEKLHKLDDALGAATAGHVADARKLVDFARTTAQREHLRYGEPIGVETLTKTITDNIQESTQSGGTRPYGASLLIGGVENGSGRLFATDPSGTPQEWKAVAIGGHREDVQAALEDGYAEDLSLEDGLALAVEALVAADEEIESDELNLVTVSEAGYEIVDEETIAELFADATADDESDETDEREE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The H. volcanii alpha1-beta-alpha2 proteasome is able to cleave oligopeptides after Tyr and thus displays chymotrypsin-like activity.
What are the official names of this protein?
Proteasome subunit alpha 2, 20S proteasome alpha subunit 2, Proteasome core protein PsmA 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPD1_HUMAN
Sequence: MPLFKLPAEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTSTEARRKKRFQGRKTVNLSIPLSETSSTKLSHIDEYISSSPTYQTVPDFQRVQITGDYASGVTVEDFEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGEDPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIAEGLKSTE
What is the function of this protein?
AMP deaminase plays a critical role in energy metabolism.
What are the official names of this protein?
AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: SYTC_BOVIN
Sequence: MSEEQASSPSAKMGDEEKPVGAGEEKQKEGSKKKNKEGSGDGGRAELNPWPEYINTRLEMYNKLKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNKAVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEEGGVSSNDFSSLETLCKKIIKEKQAFERLEVKKETLLEMFKYNKFKCRILNEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKTLKIHKNSSTYWEGKSDMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNTLIEFIRSEYRKRGFQEVVTPNIYNSRLWVTSGHWEHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRVADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSIFGFSFKLNLSTRPEKFLGDIEVWNQAEKQLENSLNDFGEKWELNPGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTFVSHDGDDKKKPVIIHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHNAKFMVDIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKTSGTVNIRTRDNKVHGERTISETIERLQQLKHSRSKQAEEEF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
What are the official names of this protein?
Threonine--tRNA ligase 1, cytoplasmic, Threonine--tRNA ligase, cytoplasmic, Threonyl-tRNA synthetase, ThrRS, Threonyl-tRNA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.