PharMolix/UniProtQA huggingface dataset:
Protein: LPQB_CORGL
Sequence: MSKISTKLKALTAVLSVTTLVAGCSTLPQNTDPQVLRSFSGSQSTQEIAGPTPNQDPDLLIRGFFSAGAYPTQQYEAAKAYLTEGTRSTWNPAASTRILDRIDLNTLPGSTNAERTIAIRGTQVGTLLSGGVYQPENAEFEAEITMRREDGEWRIDALPDGILLERNDLRNHYTPHDVYFFDPSGQVLVGDRRWLFNESQSMSTVLMALLVNGPSPAISPGVVNQLSTDASFVGFNDGEYQFTGLGNLDDDARLRFAAQAVWTLAHADVAGPYTLVADGAPLLSEFPTLTTDDLAEYNPEAYTNTVSTLFALQDGSLSRVSSGNVSPLQGIWSGGDIDSAAISSSANVVAAVRHENNEAVLTVGSMEGVTSDALRSETITRPTFEYASSGLWAVVDGETPVRVARSATTGELVQTEAEIVLPRDVTGPISEFQLSRTGVRAAMIIEGKVYVGVVTRPGPGERRVTNITEVAPSLGEAALSINWRPDGILLVGTSIPETPLWRVEQDGSAISSMPSGNLSAPVVAVASSATTVYVTDSHAMLQLPTADNDIWREVPGLLGTRAAPVVAY
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y064_SIFVH
Sequence: MSYYPVKDRIEKIIDRHNSKFSEAEIHIIDALIKWLRGNHVDITLLYMFEQLIGFDPNRIPDEDKLAIMKLILTAHPDYLLKYDKPEDIARVFKSIPGFEDILKTIFT
What are the official names of this protein?
Uncharacterized protein 64.
Protein: YQGF_SERP5
Sequence: MTNRTIIAFDFGTKSIGAAIGQELTGSARALAAFKAQDGSPDWQKIEKLLKEWQPDLVVVGLPLNMDGTEQLVTEQARKFANRLHGRFGVQIALHDERLSTVEARANLFDRGGFRALDKGSVDSASAVVILESWFERQLG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_VIBVU
Sequence: MKQILDFIPLIIFFALYKMYDIYVATGALIAATAIQIVVTYALYKKVEKMQLITFLMVAIFGGMTIFLHDDNFIKWKVTIVYAVFAIGLTVSHVMGKSAIKGMLGKEITLPESVWANINWAWVGFFTFCAGLNIYVAYQLPLDVWVNFKVFGLLAATLVFTVLTGGYIYKHLPKEQNGQSSDVPTDE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DJB11_CANLF
Sequence: MAPQNLGTLCLLLLYLLGAAIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPRAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTISLVESLVGFDMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLNQGSVQKVYNGLQGY
What is the function of this protein?
As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins.  Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed.  May help recruiting HSPA5 and other chaperones to the substrate.  Stimulates HSPA5 ATPase activity.  It is necessary for maturation and correct trafficking of PKD1.
What are the official names of this protein?
DnaJ homolog subfamily B member 11, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, Endoplasmic reticulum DNA J domain-containing protein 3, ER-resident protein ERdj3, ERdj3, ERj3p.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: VIEG_SHV21
Sequence: MALDLRNLKHLTANFSFRIMIWIMLCLALPTDSKPISTTEAPILNITQSPSLNISSPSTLEPSEPLKNCTTFLDLLWQRLGENASIKDLMLTLQREEVHGRMTTLPSPRPSSKVEEQQLQRPRNLLPTAVGPPHVKYRLYNRLWEAPKGADVNGKPIQFDDPPLPYTGAYNDDGVLMVNINGKHVRFDSLSYWERIKRSGTPWCIKTPSEKAAILKQLLKAEKKCRTTSKRITELEEQIKELEKTSTSP
What are the official names of this protein?
Immediate-early protein IE-G.
Protein: RL7_CAMC5
Sequence: MAITKEDVLEFISNLSVLELSELVKEFEEKFGVSAAPVMVAGGAVAGGAAEAAEEKTEFNLVLVDSGDKKINVIKVVRALTGLGLKEAKDAVEGTPSVLKEGISKDEAEAAKKELEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CILA_HAEIN
Sequence: MTTREQRIEKYHADRSVYQAVPKSESLSRTAKDRKLCTSLEEAIKRSGLKDGMTVSFHHAFRGGDFVVNMVMNKIAEMGFKNLTLASSSLIDSHFPIVEHIKNGVVTKIYSSGLRGELAEQISRGLLNEPVNIHSHGGRVHLVKSGELKIDVAFLGVPCCDTFGNANGFTGKSKCGSLGYARVDAEYADKVVLLTEEFVEYPHHPISIAQDQVDLIVQVEAVGDPKKIGGGATRMTTNPRELLIARKCAEVIFASGYFKDGFSLQTGSGGAALAVTRFLEEKMRRENITADFALGGITASMVALHEAGLIKKLLDVQSFDSVAAESLARNPNHIEVSANQYANYSSKGASVERLDMVILSALEIDTKFNVNVLTGSDGVIRGASGGHCDTAASAQVAIIVAPLVRGRIPTVVENVITCVTPGENVDILVTDHGVAVNPKRPDLIEALSKTDIPLFTIEQLCERAYSITGKPKEIEFTNKPVAVVRYRDGSVIDTVYQVKD
What is the function of this protein?
Represents a citrate:acetyl-ACP transferase.
What are the official names of this protein?
Citrate lyase alpha chain, Citrase alpha chain, Citrate (pro-3S)-lyase alpha chain, Citrate CoA-transferase subunit.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT2_SCHPO
Sequence: MSTKSYDYLIKLLLIGDSGVGKSCLLLRFSEDSFTPSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWFSNVEQHASENVYKILIGNKCDCEDQRQVSFEQGQALADELGVKFLEASAKTNVNVDEAFFTLAREIKKQKIDAENEFSNQANNVDLGNDRTVKRCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
GTP-binding protein ypt2, SEC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PEPE_SHEON
Sequence: MTVNALLLSSSRVGDTPYLSHAIPFIKPLTADAQKWIFIPYAGVSMNYDTYLASVVTGLSELKLDISGIHQHPDPRQALKDADGILIGGGNTFHLLHELYKYDLVQLIREEVLKGKPYIGWSAGSNVSGLSIRTTNDMPIIEPPSFAALNILPFQLNPHYSNYRAPGHNGETRAQRLLEFTRVDPITPVIGIVEGSALWRQGETLSLLGENPAYLFCGEQQEIPIPVGSDLSHLLK
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP_NEMVE
Sequence: MANVKVKIGIIGGTGVDNPNIMTDRQEKFVDTPFGKPSEPLITGNIQGVECVLIARHGRKHTVMPTDINYRANVWALKEEGCTHIVVTTACGSLTEAYRPGEIVFPDQIIDRTTKRPSTFYDGQTNSPVGVCHIPMHDPYCSVTKQILANEAQKLGIPHHASGVNVVIEGPRFSTRAESRMFRGLGGEIISMTAMPEVALANEAGLCYAAIAMVTDYDCWRDDHAPVTVESVIATFKVNVANAIKILIAAIPEIAAKDWTEIINERKSQVKPPILDSTWVMFIREYRKIGSDDASKLM
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPA_AGRFC
Sequence: MDIRAAEISAILKDQIKNFGNEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLEADNVGVVIFGSDRSIKEGDTVKRTGAIVDVPVGPELLGRVVDALGNPIDGKGPINAAKRSRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIILDTILNQKAIHDNGPDGDKLYCVYVAIGQKRSTVAQFVKVLEERGALQYSIIVAATASDPAPMQYLAPFAGCAMGEYFRDNGKHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDEMGAGSLTALPVIETQGNDVSAFIPTNVISITDGQIFLETDLFYQGIRPAVNVGLSVSRVGSAAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDASTQRLLNRGARLTELLKQPQFSPLKTEEQVAVIFAGVNGYLDKIPVAQVGKFEQGFLSYLRSEGKAILDTIRTEKAISDDTKGKLKGALDNFAKSFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GRIK3_MOUSE
Sequence: MTAPWRRLRSLVWEYWAGFLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQSLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPIDSDDSRPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWAMERLQAAPRAESGLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFIYKLRKTAEREQRSFCSTVADEIRFSLTCQRRLKHKPQPPMMVKTDAVINMHTFNDRRLPGKDSMSCSTSLAPVFP
What is the function of this protein?
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.  This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 3, GluK3, Glutamate receptor 7, GluR-7, GluR7.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein.
Protein: CHEB1_LEPIC
Sequence: MIPNPVRAVIIDDSLLVRNIISDQIQKDSKIHVVATGKTGMDCIDLAQKMNPDVIILDVEMPVMDGLTALHELQKKKLGIPVIMLSVLTQNGAEATFKALEYGAIDFVPKPSSVFQFDPEEIGNILKSKILAYFESKIQIPSQNLLKKAPAYSKVPAGSHLKKSPIQAICIGTSTGGPRALQEVFSRIPADISLPILVVQHMPAGFTKAFATRLNDHAKIKVKEAEDGEPIEPNTGYVAPGDAHLSIQSKGGRKWIALNREAPVNGHRPSIEVLLDSAIEEYKSGIIGVIMTGMGKDGSAAIVRVREIGGSTIAQDEQTSVIYGMNRQAVEMGGVEYIEPVTEIINRIQIILKERGI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COA2_TTV1K
Sequence: MKVLRLGFTDKYIEKQEPIDVVFDKYQPLGYVAVVELPSRIPWIIEIQRREWIERFITMPRDIFRELSFDIIILRRKLEPTPQYRMIRDIVSDLRQSRGYASGMVILPNGLTYDGDLLEGIEVMEGVDVIAYTLGLIDF
What are the official names of this protein?
Coat protein TP2.
What are the subcellular locations of this protein?
Virion.
Protein: PGA1_SCHPO
Sequence: MREFRLIFVLLFFLPSFAIANTEIINVETGDSNKLLTSNSVCDIELSNNSSIPLLLKPNPTIPQAAGAPQQSKYTFSVCGLKPLQKYQIRASWPAVYPSDIILNYNITHIIVEINASFYSHNESLMKRPPLVPLRLVVEPLLLGFLPKSVLPIVGFVFVIILIALICMTNLFIKHKRD
What is the function of this protein?
Essential component of the GPI mannosyltransferase 2 complex.  Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 2 subunit C167.09.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TPIS_MYCCT
Sequence: MRKKVIFGNWKMNGTNKSLEDFLYQVDNKVNNSKITAGLAVPYVMLQTGIKLAKNVKIAAQNVHFELKGAYTGEISVSMLKEIGVEYVIIGHSERREMFFETDLDINKKAKILLENNMIPIICCGESLETKEQGKTIEFVNNQINLIYQNISKQDAIKTIIAYEPIWAIGTGKTANSLDAEEVCKKIRENLAKIYDNLTAEKITIQYGGSVKPSNIQEYLKMPNIDGALVGGASLLANDYLGLVNYNE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP3_GEOSL
Sequence: MEHHKHDTFLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTIDNVYGILSLIFWTMTILVSAEYAWLAMSLGRKGQGGEIVLREIIMKLVKAGRLVAFAGFLSFVGVSLLLGDAVITPAISILSAVEGLLLIPGLEGLSTGALVAIAAAIAIGLFSVQHKGTDRVASAFGPIMALWFGTLAVTGAVSAFSMPQIVEAINPLHGIAFFRDNGLAGYFVLSEVILCATGGEALYADMGHLGKRPIVRAWHFVFVALYLNYLGQGVFAIAHPDAKNLLFGMVRSQAPALYIPFLILTIMATIIASQAIISGVFSIVYQGITTRLLPLMRVDYTSRQIKSQIYLGAVNWSLMVAVIFIMLVFRKSENLAAAYGMAVTGSMTITGIMMIIVFSHTTKKWRALVALVVTLIAAAYHVSTFSKLPHGAYWSIILASIPFVTIIIWTRGQRTLYRALKPLDLETFLISYEQIYAKGPIRGTGLFFTRETDVVPPYVVHCIIRSNIIYERNVFISLMISDEPLGVETELIRGIGPGLDAFRIEAGYMEMVDIERLLKENGIQEKVIFYGVEDISTRNPFWRFFSVLKKLTPNFVQFHKLPASRLQGVVTRVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 3.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HOA1_NOCSJ
Sequence: MNAHQIFVQDVTLRDGMHAVRHRIGLDDVRRIVAALDAAGVDAIEVAHGDGLAGSSVNYGPGSHTDWEWIEAAADVLERARLTTLLLPGVGTIHELKTAYDLGVRSVRVATHCTEADISAQHITAAREIGMDVSGFLMLSHMAPPAELAKQALLMESYGAHCVYVTDSGGRLTMNDVRDRVAAYRDVLDPATEIGIHAHENLSLSVANSVVAVETGAVRVDASLAGHGAGAGNCPIEAFVAVANLSGFEHGCDLFALQDAADDLVRPLQDRPVRVDRETLTLGYAGVYSSFLRHAERAADQYGVDVRELLMECGRRGLVGGQEDMIIDIALDQVGAVAS
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HIS4_ACTPJ
Sequence: MQKKSIIIPALDLIDGNVVRLHQGDYAKQTTYSDNPIEQFANYLAQGAEQLHLVDLTGAKDPAKRQTALIGKIIAETNCQIQVGGGIRTEQDVADLLAVGANRVVIGSTAVKDRAMVKGWFEKYGAEKFVLALDVNIDASGQKIIAISGWQEASGVSLEELIEDYQVVGLQHVLCTDISRDGTLAGSNVNLYREICAKYPKIHFQSSGGIGSLDDIKALKGTGVSGVIVGRALLEGKFNVAEAIECWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF_PORPU
Sequence: MQTTIQKEEAPNRETLLTPRFYTTDFEEMASMNISENEQDFFAILEEFRADYNSQHFIRGEEFNQSWSNLETKTKSLFIEFLERSCTAEFSGFLLYKELSRKLKDSNPIIAECFLLMSRDEARHAGFLNKAIGDFNLSLDLGFLTKTRKYTFFSPKFIFYATYLSEKIGYWRYITIYRHMEQYPEHRIYPIFKFFENWCQDENRHGDFFAALLKSQPHFLNDWKAKMWCRFFLLSVFATMYLNDFQRIDFYNAIGLDSRQYDMQVIRKTNESAARVFPVALDVDNPKFFKYLDSCACNNRALIDIDKKGSQPLVKTFMKAPLYMSLILNLIKIYLIKPIDSQAVWNTVR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UREF_AZOVD
Sequence: MNGMWALLRLASPQLPIGGYSYSQGLELAIERGLVCDPPTARRWLEDQLLLNLARFEAPLLLAQCRAAADGDWTALEALAERHRASRETRELHLESRQMGFSLRQLLEDLPELDEPSRAVFARLVEPGLAPAWALAARAWGIAPEDALAAWLWSWLENQLAVLMKSLPLGQQAAQRLTSALLPALGQAQRTACAHAPDDWGTVAFGLTLASMAHERQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_EXIS2
Sequence: MTLTAPRKHAIEQDQQDALAPYRNEFYLQEGSIYMDGNSLGLLSKRAEATLLESLADWRELGIDGWMKGRHPWFDLSEKLAALNAPLVGGRADEVMVTGSTTVNLHQLVATFFAPSGRRTKILADSLTFPSDIYALQSQLRLRGLDPAEHLVQVESRDGRFLDEADIIAAMTDDIALIVLPTVLYRSGQILDMERLTREAHARGILIGFDGCHSVGAIPHAFHDWGVDFAYWCNYKHLNGGPGTVGGLFVHERHFGTLPGLTGWFGSRKDKQFDMNHTMTPAENAAAFQIGTPHVLSLAPQIGALELFAEVGIDAVRAKSLALTDYMMTLVDQELTAYGFVIGNPRDAKRRGAHLSLEHPEAARICKALKAHQVIPDFRAPNIVRLAPVALYNSFEDVYEVVSILKTIMDEKQYEQFKNEREVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: GLMU_ACTP7
Sequence: MTQLSVVILAAGKGTRMYSDLPKVLHTVAGKPMVQHVIDTAKQIDAKQIHLIYGHGGELLQQRLSSEPVNWVLQAEQLGTGHAMQQAAPFFADDENILMLYGDAPLITKETLERLIAAKPENGIALLTVELENPTGYGRIIRENGSVVAIVEQKDANAEQLKIREVNTGVMVASGASFKKWLANLNNNNAQGEYYITDVIAMANQDGYKVQAVQASEFMEVEGANNRLQLAALERFYQKTQAEKLLLAGVRLIDQARFDIRGSLTHGKDVEIDVNVIIEGEVKLGNRVRIGAGCVLKNCEIGDDVEIKPYSVIEDAVVGKAAQIGPFSRLRPGANLAEETHVGNFVEIKNAQVGKGSKVNHLTYVGDAEVGSNCNIGAGVITCNYDGANKFKTIIGNNVFVGSDSQLVAPVTIADGATIGAGATVTKDVAENELVISRVPQRHIQGWQRPTKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPP_CERCE
Sequence: MVLISVLASLLVLQLSYAQKSSELVIGGAECNINEHRSLVLLYNSSRLFGGGTLINKEWVLSAAHCDGENMKIYLGLHHFRLPNKDRQIRVAKEKYFCRDRKSIVDKDIMLIKLNKPVNNSTHIAPLSLPSSPPSVGSDCRIMGWGTITSPNDTYPKVPHCANINILEHSLCERAYNDLSASSRTLCAGIEKGGIDTCKGDSGGPLICNGQIQGIVSWGDEVCGKPNKPGVYTKVFDYTDWIRNIIAGNTAATCPQ
What is the function of this protein?
Thrombin-like snake venom serine protease which potently induces platelet aggregation and has fibrinogenolytic activities.  Clots purified fibrinogen and hydrolyzes alpha-chains (FGA).  High concentrations of this enzyme also cleave prothrombin (F2) and factor X (F10).  Is also able to activate factor XIII (F8).
What are the official names of this protein?
Thrombin-like enzyme cerastocytin, SVTLE, C.cerastes platelet proaggregant protein, CC-PPP, Factor VIII activator, Fibrinogen-clotting enzyme, Proaggregant serine proteinase, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KIT_FELCA
Sequence: MRGARGAWDFLCVLLLLLRVQTGSSQPSASPGEWSLPSIHPATSELIVSAGDEIRLLCTDPGFVKWTFETLGQSSEITHNEWITEKAEATNTGNYTCTNGGGLSSSIYVFVRDPAKLFLVDLPLYGKEDHDTLVRCPLTDPEVTNYSLRGCEGKPLPKDLTFVTDPKAGITIRNVKREYHRLCLHCSADRKGKSVLSKKFTLKVRAAIRAVPVVSVSKASHLLREGEEFSVMCLIKDVSSSVDSMWIKENSPQTNAQPQSNSWHQGDFNFVRQERLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVAKGFINIFPMMNTTIFVNDGENVDLIVEYEAYPKPEHQRWVYMNRTLTDKWEDYPKSDNESNIRYVSELHLTRLKGNEGGTYTFQVSNSDVNSSVTLNVYVNTKPEILTHESLVSGILQCLVAGFPEPTVDWYFCPGAEQRCPVPVGPLDVQMQNSSVSPSGKLVVQSSIDYSAFKHNGTVECRASNNVGKTSAFFNFAFKGNSKEQMHPHTLFTPLLIGFVIAAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEVALYKNLLQSKESSCNDSTNEYMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANCSPNRERPTAVDHCVRINSVGSSTSSTQPLLVHEDA
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.  In response to KITLG/SCF binding, KIT can activate several signaling pathways.  Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL.  Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase.  Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1.  Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.  KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor.  Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.  Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1 (By similarity).
What are the official names of this protein?
Mast/stem cell growth factor receptor Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL6_PSEA7
Sequence: MSRVAKNPVKLPAGVEIKLAGQQLSIKGAKGALELKVHPSVEVIQDSGELRFAARNGDQQTRAMAGTTRALVNNMVVGVSQGFERKLQLVGVGYKAQAKGQVLSLSLGFSHPVDYELPAGIVAETPSQTDILIKGIDKQLVGQVAAEIRDFRPPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.