PharMolix/UniProtQA huggingface dataset:
Protein: PLSY_EHRRW
Sequence: MDFQVVIFILCYLIGSIPFGFILSYVIGIGDIRKTGSGNIGATNVFRKNKKLALLTLLLDALKSFICVAIAQKYNIDNTILFLAALFAIIGHMFPVYLFFKGGKGVAPLLGSLIFIDYRVAVCFLTFWIICFLLCKYASLSSIVSTLIALLFICTCYTIVQSVIFTITALLIITQHTDNIIRMLNKSENKINLKL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_DESAL
Sequence: MAKLRVHELARELNMTNKVLLDKLQAMDLPTPVRSHMSSLDDDVVALVKASLVRPKAKSVVEKRIGTTVIRRRKKVVKPAEGGPEETAKPEEGAEEGVQEMDAAQESVSAPEAEKAPEPVAEKAPEPQKAAPAAEEPKAEEGAPAPEKAAPVQAKEEPEEAPQAEAKPAPPKKVDVTPPGDKAKIIAKPEPPQPAEPEPPKEEPAPVELPEEKQAVSAKAADTPAEPQEEPEAKPEIKAEAKAEEGAPEKPAEEPKAKEEQKAAPEDSKEEPKAEEPAQPAEDEKAEEKAKAPEEKEPAKSQEPQAAKEPSKEAPKPKGKKKKKKETAAKIISLPTRPVEPVVPPASRQKPAPQSPAGPGGPGGPGVPPQPRAPQDLGGDPAAKKEKRKKKGRRDGGTTEETDSKFFKKKISFRKKAVVEGADLYDKTPGKLRKGKKGGKAQPVRQQKTQTTTPKAIKRRIKIDEAIAVADLAKRLGIKAAELIKNLMGMGIMATVNQMLDYDTAVLLAAEFGYEVEKANFEEETVLKAEEDAPETLSNRPPVVTIMGHVDHGKTSLLDAIRESNVTGGEAGGITQHIGAYLVDSPRGRIAFLDTPGHEAFTAMRARGAQVTDIVILVVAADDGVMPQTVEAVNHSKAAGVPIIVAVNKMDKEGADPDRVMRELSDHGLVPEDWGGDTIFVQVSAKQRQGLDDLLEMVLLQAEVLELQANPDKLARGHVVEAKVDPGRGPVATVLIQEGTLHAGDVVVCGIHYGKVRAMYNEKRQPLDAAGPACPAEILGLSGVPMAGDEIIAVDDEKVAKQVSSHRAQKQRATELAKSSKLSLDNLFDQMQAGNVKDLNLIIKADVQGSIEALRESLEKLSGDEVKIHVVHAATGTVLESDVALAAVSNAIIVAFNVRPSPKVSDMAAEEHVDIRFYDIIYNAINEIKDAIVGLMESTYKEHVSGRAEVRDTFTIPKVGTIAGCYVTDGKVERHNQVRLLRDGVVIFDGKLSSLRRFKDDVKEVATGYECGMGIENFNDIKIGDVLELYYLEEIKPVLK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_FRATT
Sequence: MQVTVEKKEGIHCSLLIEVPANEIDSVVSKEINRTAKTIKMDGFRPGKVPAGMVKKKYGEQIRMEVISDLIPQKYSKAIQDEKLAVAGIEVELKENKEGQPLKFVANLELFPEFEVTGFEKIEVQKPVVELTDKEVKQMIENLRKQFATFSEVDKVVEKDDKVTIDFVGKKDGEAFEGGTANDIDVIIGSGQMIPGFEDGIIGMKKGEQKTITVTFPQDYQNKDLAEAETTFDITVKKIQQAELPEVNDEFVKKFGVKGGVDTFENEIKENMQRELKFILQRKVKDQVFKGLREIAEFETPKSLIKREIDAAKQNLLKQMGGAKGFDVNQLSDNLFEANAKQKVETSLILDSIMNSQEFKAEEAEVESLLDELVQAYEEPEKTKEQIKKNDKEIANLKALVIENKLTDWVLEQAKVTEKTEDFFEVIKENMQAQQAGF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: IXTPA_BORPA
Sequence: MSAEILNPNLRRVVLASNNAGKLREFSALFAPLGIELVPQSELGVSEAAEPHATFVENALAKARHASRHTGLPALADDSGLCVVALGGAPGVHSARYAQQPGGARSDAANNALLVRELAAAGDRRAWYVALLALVRTENDPCPLIGEGLWHGEIVDAPAGEHGFGYDPHFYLPQQGCTAAQLAPEHKNRISHRAQALAQLLDKLRATGPVDRP
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: PTFLA_ECOLI
Sequence: MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQTLLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGVPQSGEEDQVKIIGTLCRKIIHKEFIHQLQQGDTDQVLALLNQTLSS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FrvAB PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-like EIIA component, Fructose-like phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_HAMD5
Sequence: MARLHDYYKDIVIKEMMCKFSYASVMQVPRVTKITLNMGVGEAVSDKKLLDSAMSDLAAISAQKPLVTKARKSVAGFSIRQGYPIGCKVTLRGKRMWEFLERLLSIAIPRIRDFRGLSKKSFDGRGNYNMGVSEQIIFPEINYDAIVKIFGLDISITTTAKSDDEGLALLAAFKFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ASIP_CEBPY
Sequence: MDVTRLVLATLLVFLCFFAAYSHLPPEEKLRDDRSLRSNSSVNLLDLPSVSIVALNKKSKKISRKEAEKRRSSKKEASKQKVARPRTPLSVPCVSTRGSCKPPAPACCHPCASCQCRFFRSACSCRVLNVNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: POLC3_SYRVU
Sequence: MAEEVAELERIFKRFDANGDGKISSSELGETLKTLGSVTPEEIQRMMAEIDTDGDGFISFEEFKDFARANSGLIKDVAKIF
What are the official names of this protein?
Polcalcin Syr v 3, Calcium-binding pollen allergen Syr v 3.
Protein: Y836_MYCTO
Sequence: MCSGPKQGLTLPASVDLEKETVITGRVVDGDGQAVGGAFVRLLDSSDEFTAEVVASATGDFRFFAAPGSWTLRALSAAGNGDAVVQPSGAGIHEVDVKIT
What are the official names of this protein?
Uncharacterized protein MT0836.
Protein: MMM1_NEUCR
Sequence: MADICPSRSEPTLSFTQGLILGQLSVVLLLAAFIKFFIFGDPPSPEVVASIRATDRRSRTLAHKKSILSLRETNALQLVQNPALNKKHVLRPGPPILTIGSILSKTYYKVDSHQPESLDWFNVLIAQTIAQFRSDAQHDDAILSSLSKALNGTARPDFLDEIKVTELSLGEDFPIFSNCRIIPVDEDGLSFGTGKAFDANMATREGARLQARMDVDLSDMITLAVETKLLLNYPKRLSAVLPVALAVSVVRFSGTLSISFIPSNPSNNEPAKMIFTFLDDYRLDFSIRSLLGSRSRLQDVPKIAQLVESRLHRWFDERCVEPRFQEIALPNMWPRKKNTRGGDETISDVERSMSKAKGVDIAKDVREEARKEIEAEAHGGADRVPDSLRYRHRPRADEEFPGAGSMPGSMPGSMP
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria (By similarity).  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria (PubMed:10982393).  The mdm12-mmm-1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm-1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm-1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids (By similarity).
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: LAMP2_CRIGR
Sequence: MMCFRLSPVSGSGLVLSCLLLGAVQSYAFELNLPDSKATCLFAKWKMNFTISYETTTNKTLKTVTISEPHNVTYNGSSCGDDQGVAKIAVQFGSTVSWNVTFTKEESHYVIGSIWLVYNTSDNTTFPGAIPKGSATVISSQSIEIPLDDIFRCNSLLTFKTGNVVQNYWDIHLQAFVQNGTVSKEEFVCEEDKSVTTVRPIIHTTVPPPTTTPTPLPPKVGNYSVSNGNATCLLATMGLQLNVTEEKVPFIFNINPSTTNFTGSCHPQTAQLRLNNSQIKYLDFIFAVKSESHFYLKEVNVSMYMANGSVFSVANNNLSFWDAPLGSSYMCNKEQVVSVSRTFQINTFNLKVQPFNVTKGKYATAQDCSADEDNFLVPIAVGAALAGVLALVLLAYFIGLKRHHTGYEQF
What is the function of this protein?
Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live.  Functions by binding target proteins, such as GAPDH, NLRP3 and MLLT11, and targeting them for lysosomal degradation.  In the chaperone-mediated autophagy, acts downstream of chaperones, such as HSPA8/HSC70, which recognize and bind substrate proteins and mediate their recruitment to lysosomes, where target proteins bind LAMP2 (By similarity).  Plays a role in lysosomal protein degradation in response to starvation (By similarity).  Required for the fusion of autophagosomes with lysosomes during autophagy.  Cells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes.  Required for normal degradation of the contents of autophagosomes.  Required for efficient MHCII-mediated presentation of exogenous antigens via its function in lysosomal protein degradation; antigenic peptides generated by proteases in the endosomal/lysosomal compartment are captured by nascent MHCII subunits.  Is not required for efficient MHCII-mediated presentation of endogenous antigens (By similarity).
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 2, LAMP-2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, Lysosomal membrane glycoprotein B, LGP-B.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, autophagosome membrane. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Protein: PRP18_XENLA
Sequence: MDILKAEIARKRKQLEEKALVGGEKKYFKRSELTAKEKEEYFERCGYKMQKEEEEEKPSSSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYETFQRLRKIEILAPEVNKGLRNDLKAALDKIDQQYFNELVAGQETTDEDTQNDLKVHEENTTIEELEVLGECLGQGDDNKDMDTINKVLKFLLGVWAKELNAREDYVKRSVHGKLASATQKQTESYLKPLFRKLRKKNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKYFSTDPSKCVEYNAL
What is the function of this protein?
Participates in the second step of pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor 18, PRP18 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRP18 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Protein: NUON_BACFR
Sequence: MDYSQFLYMKEELSLIAVILILFVVDLLTCPDQKGATPKVNVRSLTLPAVILMTLHTVINLFPGTPAEAFGGMYQYTPMQTIIKAVLNVGTIIVLLMAHEWLKREDTRIKQGEFYVLTLSTLLGMYFMISAGHFLMFFIGLEMASIPMAALVAFDKYRHHSAEAGAKYILTALFSSALLLFGLSMIYGTSGTLYFNDLPGHITGNMLQIMAFVFFFAGMGFKISLVPFHLWTADVYEGAPTAVTSYLSVISKGSAAFVLMTILMKVFAPMVAQWQEVLFWVTIASITIANLFAIRQQNLKRFMAFSAISQAGYIMLGVIGGSEMGMTALVYYVLVYLAANLGVFAVISIVEQRSNKVEIDDYNGLYKTNPKLAFIMTLALFSLAGIPPFAGFFSKFFIFMAAFNSGFHLLVFIALINTVVSLYYYLLIVKAMYINPNEEPIPTFRSDNYTKVSLVLCTLGIIALGIASCIYQGIDKFSFGMGM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO_HALSA
Sequence: MTRIEAVRYRPILDSRGNKTVEAEVTTDDGGFGRAAAPSGASTGEHEAVELPVGEAIAAGRERIAPRLEGREFAGDQRGVDAALHAADDTTDFSAVGANVAVATSMAAAKAAADVLGVHTYQHLGGALRGRNFPVPLGNVLGGGAHAADATAIQEFLVAATGAPSVRQAVFANAAVHQRVKDRLDDDGVPAAKGDEGAWAPSIDDATAFDVVAGAAAEVADEFGFDVRLGLDLAAAERYDGDEYVFGDDRRSTAAQIEYVAGLVSEYDLAYVEDPLDENDFEAFAELTDRVGDETLVCGDDLFVTNTERLQRGIDAGAANSILVKPNQIGTLTDAVDAIELATRNGYDAVVSHRSGETEDTTIAHLAVATDAPFIKTGAVGGERTAKLNELIRIADEA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPD_SORC5
Sequence: MSYESVARRYGRAIFEIGKETGTLAALAREIGDASAMYSASEELRLVLDNPLIPEASREELLRELGGRAAFSDVTKNTLLLLARRRRLAALPEIARQLALLVDQDQNVARAVVTSAGPLSDGYLDRLRAELEKATGRKISVTHRQDPSLIAGVVTQIDDQVIDGSLRTRLSSFRDNLLRT
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSAJ_TETOB
Sequence: MKNFTTYLSTAPVVATGWFIVTAALLIEINRFFPDPLVFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PGA59_CANAL
Sequence: MQFSSAIILSAVAGSALATYANSTVTDIATTVVTITSCEENKCHETEVTTGVTTVTEVETTYTTYCPLPTAKAPVASTSNSTTTPPVSTAEGAAAANAVPAVAAGLLALGAFM
What is the function of this protein?
Cell wall protein necessary for cell wall integrity.  Plays only a minor role in hyphal morphogenesis and is not critical to biofilm formation.
What are the official names of this protein?
Cell wall protein PGA59, GPI-anchored protein 59.
What is the protein family that this protein belongs to?
Belongs to the HWP1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: SAHH_PNECA
Sequence: SCRYFLAEWGRKEIELAENEMPGLISCRRNMRFKPLRVQIAGCLHMTIQTAVLIETLVELGAEVTWSSCNIFSTQDHAAAAIAASGISVFAWKGETEEEYLWCIETQLTSFKDGKHLNMILDDGGDVTSLVHNKYPDYLKNCKGISEETTTGVHQFYKMLKEGKLKVPAINVNDSVTKSKFDNLYGVSLVLIYKIISNIKLRCRESLIDGIKRATDIMIAAKVAIVAGFGDVGKGCAKALRGMGARVIITEIDPIVALQASMEGYQVAVMEEVADQADIFVTATGCKDIICERHFEAMKNDAIICNIGHFDVEIDVAWLIKKCSSISNIKPQVDRYLLGNGRNIILLAEGRLVNLGCATGHSSMVMSMSFTNQVLAQIALWTAQEGQYPLGVHFLPKKLDEEVARLHLSKLGKLTSLTPEQSAYLDIPIDGPYKSEHYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: CNG13_ARATH
Sequence: MAFGRNNRVRFRDWISEGTEYGYGRNKARPSLNTVLKNVRRGLKKPLSFGSHNKKRDSNSSTTTQKNIINPQGSFLQNWNKIFLFASVIALAIDPLFFYIPIVDGERHCLNLHRNLEIAASVLRTFIDAFYIIHIVFQFRTAYISPSSRVFGRGELVDDPKAIAIKYLSSYFIIDLLSILPLPQLVVLAVIPNVNKPVSLITKDYLITVIFTQYIPRILRIYPLYTEVTRTSGIVTETAWAGAAWNLSLYMLASHVFGALWYLISVEREDRCWREACEKIPEVCNFRFLYCDGNSSVRNDFLTTSCPFINPDDITNSTVFNFGIFTDALKSGIVESDDFWKKFFYCFWWGLRNLSALGQNLNTSKFVGEIIFAVSICISGLVLFALLIGNMQKYLESTTVREEEMRVRKRDAEQWMSHRMLPDDLRKRIRRYEQYKWQETRGVEEENLLRNLPKDLRRDIKRHFCLDLLKKVPLFEIMDEQLLDAVCDKLKPVLYTENSYAIREGDPVEEMLFVMRGKLMSATTNGGRTGFFNAVYLKPSDFCGEDLLTWALDPQSSSHFPISTRTVQALTEVEAFALAADDLKLVASQFRRLHSKQLQHTFRFYSVQWRTWGASFIQAAWRRHCRRKLARSLTEEEDRFRNAITKRERNAASSSSLVATLYASRFASNALRNLRTNNLPLLPPKPSEPDFSLRNP
What is the function of this protein?
Putative cyclic nucleotide-gated ion channel.
What are the official names of this protein?
Putative cyclic nucleotide-gated ion channel 13, Cyclic nucleotide- and calmodulin-regulated ion channel 13.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIG_PSEF5
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVGLAGKKVLDVGCGGGILSEAMAQRGATVTGIDMGEAPLAVAQLHQLESGVNVEYRQITAEALAEEMPEQFDVVTCLEMLEHVPDPSSVIRACFRMVKPGGQVFFSTINRNPKAYLFAIIGAEYIMKLLPRGTHDFKKFIRPSELGAWSRSAGLTVKDIIGLTYNPLTKHYKLAPDVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SEC31_ASPOR
Sequence: MVRLREIPRTATFAWSPGAASPLIATGTRAGAVDVDFSNETCLELWDLGLDRQSTGEELQPIAKFDTDSGFNDLAWTPSEDNTRGIIAGALESGSLDLWDADKLINGSSDDAVISRTSKHSGAIKALQFNPRHSNLLATGGAKGELYISDLNNVANPYRLGTAARADDIECLDWNKKVAHILVTGSSAGFVTVWDVKTKKESLTLNNMGRKAVSAVAWDPEKPTKLVTATPLESDPMIYVWDLRNSHAPERVLKGHESGVLSLSWCSHDPDLLLSSGKDNRTLCWNPQTGHAYGEFPVVTNWTFQTRWNPHNPNFFATASFDGKIAVQTVQNTSTDTAQAIADQNQALDGEDFFAKAQTQPQVSSFSLPKAPKWLERPCGATFGFGGRVVSVNLVEKGQRASKIKITPFEVDEAVGQSTETFENALKEGDLRSICETRAANAATEEEKADWKVIQALISENPRKGLAEYLGFQDQSADEAADKLANLGLGKEETNGESPKESRGPGAKKHKRLQSMFDASPEADNFLSDLAASKGAKTNNPFHIFNGSETEADKGITRALLLGDFEKALDVSLKEDRLSDAFMIAICGGQKCIAKAQEHYFSKQTESPNYVRLLASIVGKNLWDVVYNADLSNWKEVMAALCTFAEEKEFADLCDALGDRLEEQIRASDDKSLRKDASFCFLAGSKLEKVVAIWIEELRENEQKALETAANDTSFSIHVRALQGLIEKVTIFRQVTKFQDTERTKESDWKLSNLYDKYIEYADVVATHGRLQVAQKYLDLVPEKHPEAEVARNRIKLATRQPTAQKTQQTTTGRGTPLNKPLPTTNAYQPQRTFSPVATAAAPSPYAPPAPTTNAYAPPAAATNPYAPPAAATNPYAPPAPASNPYAPPGAAAPPQPTNPYAPASGGSYAPTGYQPTPAPSYGAKPLGGSVPPPPRASNQSPATVTTYTTATNLPAWNDLPEGFAKAPTPRRGTPAGAAAPISSPFPNQSPSIAQGPPPPGAPPTQRTPSVPPPPKGTAPPPRVTSPPSAIPPGPTPPPNPYASLPQSPPQLNPGTMGVPAPIPRGPSPYNAPPSMPPPTNRYAPSPAAQAANPQLQARGPVPPPPQAAASPYAPQPPAASQYAPSTPPLQQGPPPASTSRPGTASSQKVTPAPATPKYPPGDRSHIPEDAMPIYEILSADMQRIKGRAPTSFKQQVEDADRRLNLLFDHLNNGDLLKPNTVSDMADLARAIQARDYEAARAIHVDILTNRTDECGQWMVGVKRLISMSKATP
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL20_VIBC3
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRAKKRQFRQLWIARINAAARQNGLSYSRFINGLKKASIEIDRKILADIAVFDKAAFAVLVEKAKGAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CTR1_HUMAN
Sequence: MGCKVLLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMASTSDELDPADQNELASTNDSQLGFLPEAEMFSLKTILSPKNMEPSKISGLIVNISTSLIAVLIITFCIVTVLGREALTKGALWAVFLLAGSALLCAVVTGVIWRQPESKTKLSFKVPFLPVLPILSIFVNVYLMMQLDQGTWVRFAVWMLIGFIIYFGYGLWHSEEASLDADQARTPDGNLDQCK
What is the function of this protein?
High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.
What are the official names of this protein?
High affinity cationic amino acid transporter 1, CAT-1, CAT1, Ecotropic retroviral leukemia receptor homolog, Ecotropic retrovirus receptor homolog, Solute carrier family 7 member 1, System Y+ basic amino acid transporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.