PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_BORA1
Sequence: MDIRRTVLWMIFSFSLLLLWNNWQIHNGQPALFGGPSPEQNAPATANNQAATNPASNTPAVPNAPAATSAPSSVPGSTAPAPAQAQEVVITTDVLRLTFSSTGAQIIRAELLKYPATAGSDQPMVLLDRSAGLTYTAQTGVIGAGQNFPTHLTPFAVTTNERELTGDKLVVRFEAESGGLRVIKTFTLDRGSYDVHVRHDVTNVGTAAQHPSVYLQLERDGNDPAGTSSFYHTFTGVAVYSEQDKFQKVTFSDIAKNKASYIKQADNGWIGIVQHYFATAWVPKEGTPRTNDLLQLQPNLFAARAIEALGEVAPGATVSSDAQLWVGPQDQQAMAAVAPGLELVVDYGWLTIIAKPLFTLMTWLHSLLGNWGWTIVALTVIIKAVFYPLASASYRSMARMKQVAPRLQALKEKYGDDRQKLNQAMMEMYRTEKINPLGGCLPMVVQIPVFIALYWVLLASVEMRGAPWILWIHDLSVRDPYFILPAVMMATMFLQIKLNPTPPDPVQAKVMMVMPLVFGGMMFFFPAGLVLYWCVNNTLSILQQWSITRSITRQTAKRG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_PSECS
Sequence: MTNIRKTHPLMKIINNAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLAVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFTLHFILPFIITALTATHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALLLILTLLTLTLFTPDLLGDPDNYIPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLVFWTLIADLLTLTWIGGQPVEHPYIILGQLASILYFLLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IF3_SALTY
Sequence: MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3078_VIBC1
Sequence: MSTPFWQSKSLEHMTEEEWESLCDGCGKCCLHKLMDEDTDEIYYTNVACSWLNSKTCSCKDYPNRFTSGEECTKLTREDIDDFTWLPHTCAYRLLAENQPLPEWHPLITGSKSAMHAAGESVRNKVVYEIDVVDWEDHIQNLPDRLKPHN
What are the official names of this protein?
UPF0260 protein VIBHAR_03078.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: NDHL_PROMM
Sequence: MFLQAVTSPISINSLMVLAAYALLGGLYLIVVPLLLYSWMNRRWHCMGKFERLSAYGLVFLFFPGLILFAPFLNLRLNGQGEV
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: DDL_AERS4
Sequence: MKNMHVLLLCGGGGSEHEVSLRSANFLEQQLGLVPGVEVTRVEMFADRWFSADGRECKLGLDKLLSFDSVARPVDYVVPCIHGYPGETGDLQSFLELAGLPYLGCDAEASKICFNKISTKLWLSAIGIPNTPYLFLTEQNDAALTEAKAALAKWGKVFIKAASQGSSVGCYSASNETDLLQGIKDAFGYSEQVLIEKAVKPRELEVAVYQYGDELIATYPGEICVPQDKFYTYEEKYSSASHTATSLKAEGLTQAQADAIHEYALKAFRQLKLTHLSRIDFFLTEEGEILLNEINTFPGMTSISMFPKLLEHHGHSFAHYLEQILRKPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CL042_HUMAN
Sequence: MSTVICMKQREEEFLLTIRPFANRMQKSPCYIPIVSSATLWDRSTPSAKHIPCYERTSVPCSRFINHMKNFSESPKFRSLHFLNFPVFPERTQNSMACKRLLHTCQYIVPRCSVSTVSFDEESYEEFRSSPAPSSETDEAPLIFTARGETEERARGAPKQAWNSSFLEQLVKKPNWAHSVNPVHLEAQGIHISRHTRPKGQPLSSPKKNSGSAARPSTAIGLCRRSQTPGALQSTGPSNTELEPEERMAVPAGAQAHPDDIQSRLLGASGNPVGKGAVAMAPEMLPKHPHTPRDRRPQADTSLHGNLAGAPLPLLAGASTHFPSKRLIKVCSSAPPRPTRRFHTVCSQALSRPVVNAHLH
What are the official names of this protein?
Uncharacterized protein C12orf42.
Protein: PEPB_YERPE
Sequence: MTTEIMQISLSHNPADARWGEKALISTNDQGVTIHLTSHDQLGGIQRAARKIDGQGIKQVKLAGEGWGLEQSWAFWQGFRGPKGQRSVVWAELPANEKTELEQRLKIIDWVRDTINAPAEDLGPEQLAKNAIDLLCAVSCDAVSYRITKGEDLREQNYAGIYTVGRGSDRAPVLLALDYNPTGNPDAPVMACLVGKGITFDSGGYSLKQSAFMDSMKSDMGGAATLTGALALAAARGLKERVKLYLCCADNMVSGNAFKLGDIIRYRNGKTVEIMNTDAEGRLVLADGLIDASEQNAPLIIDAATLTGAAKTALGNDYHALFSFDDELAQALLNSAHSEHELFWRLPLAEFHRSQLPSNFAELNNVAGGAYSAGASTAAAFLSHFVKNYQQGWLHIDCSATYRKSAVDQWSAGATGLGVRTVANLLLAQAKQ
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISLR_MOUSE
Sequence: MRALCLLCWAVLLNLVRACPEPCDCGEKYGFQIADCAYRDLEGVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRSVAIGALAPLSHLKSLDLSHNLLSEFAWSDLHNLSALQLLKMDSNELAFIPRDAFSSLSALRSLQLNHNRLHALAEGTFAPLTALSHLQINDNPFDCTCGIVWFKTWALASAVSIPEQDNIACTTPHVLKGIPLGRLPPLPCSAPSVQLSYQPSQDGAELRPGFVLALHCDVDGQPVPQLHWHIHTPGGTVEIASPNVGTDGRALPGALATSGQPRFQAFANGSLLIPDFGKLEEGTYSCLATNELGSAESSVNVALATPGEGGEDAVGHKFHGKAVEGKGCYTVDNEVQPSGPEDNVVIIYLSRAGPPEAAIAADGRPAQQFSGILLLGQSLLVLSFFYF
What are the official names of this protein?
Immunoglobulin superfamily containing leucine-rich repeat protein.
What are the subcellular locations of this protein?
Secreted.
Protein: E3GL_ADE1A
Sequence: MGPILVLLVLLSLLEAGSANYDPCLDFDPENCTLTFAPDTSRICGVLIKCGWECRSVEITHNNKTWNNTLSTTWEPGVPQWYTVSVRGPDGSIRISNNTFIFSKMCDLAMFMSKQYSLWPPSKDNIVTFSIAYCLCACLLTALLCVCIHLLVTTRIKNANNKEKMP
What is the function of this protein?
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface.  Also delays the expression of class I alleles that it cannot affect by direct retention.  Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity).
What are the official names of this protein?
Early E3 18.5 kDa glycoprotein, E3-19K, E3gp 19 kDa, E19, GP19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E19 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: IDI2_SULIA
Sequence: MPDIVNRKVEHVEIAAFENVDGLSSSTFLNDVILVHQGFPGISFSEINTKTKFFRKEISVPIMVTGMTGGRNELGRINKIIAEVTEKFGIPMGVGSQRVAIEKAEARESFAIVRKVAPTIPIIANLGMPQLVKGYGLKEFQDAIQMIEADAIAVHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGISMETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLNWGVPTAASIMEVRYSVPDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSAIEGKESLEQFFRKIIFELKAAMMLTGSKDVNALKKTSIVILGKLKEWAEYRGINLSTYDKVRKRE
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCO4_SOLLC
Sequence: MENFPIINLENLNGDERAKTMEMIKDACENWGFFELVNHGIPHEVMDTVEKLTKGHYKKCMEQRFKELVASKGLEAVQAEVTDLDWESTFFLRHLPTSNISQVPDLDEEYREVMRDFAKRLEKLAEELLDLLCENLGLEKGYLKNAFYGSKGPNFGTKVSNYPPCPKPDLIKGLRAHTDAGGIILLFQDDKVSGLQLLKDEQWIDVPPMRHSIVVNLGDQLEVITNGKYKSVMHRVIAQTDGTRMSLASFYNPGNDAVIYPAPSLIEESKQVYPKFVFDDYMKLYAGLKFQPKEPRFEAMKAMEANVELVDQIASA
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase 4, ACC oxidase 4, Ethylene-forming enzyme, EFE, Protein pHTOM5.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PFA4_ASPFU
Sequence: MLCRSFNISQLAIPFVSVLISFLAYTSQLFFYYFEEAPLRSEEFWRLNIFAVCIWVCYYRACTVDPGRIPKDWTPPNLKQLEKDCAGGRQRWCRRCEAFKPPRAHHCKTCQRCIPKMDHHCPWTSNCVSHFTYPHFMRFLFYAVVGMGYLETLLFERASIVWASRHLPSYLGPGLGQLVHLFILLVVNSLTWLALFILLLRSIWSLALNTTTIESWEIERHETLLRRARHFGGYLSGPGGIQIRIKKQEFPYDIGIWSNIRAGMGGSANVLSWFWPFAATPDRSTGLEFEVNGFEDPNLSWPPPDPDRIPLPAKREDMSAAIAAADASYHRALQARNIQRSNDASHSGGHPIQRRKRFHDRFNENKAKERLSESESDFSDDEEVQDGEEGWKNSEGDRLRDFGVDEEAEFYDEEDIPLGILMQRRRQQ
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase pfa4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ASSY_NITEU
Sequence: MDKVKKAVLAFSGGLDTSVILKWLQDTYQCEVVTFTADIGQGEEIEPARAKAVQFGIREIFIEDLREEFVRDYVFPMFRANTIYEGEYLLGTSIARPLIAKRQVEIAQQTGADAVSHGATGKGNDQVRFELGYYALQPDIRVIAPWREWDLTSREKLLTYAEKQGIPIEMKQKAGSPYSMDANLLHISYEGRALEDPAAEPEESMWRWTVSPETAPSEPEYLDLEYERGDIVALNGERLSPAAILTRLNQLGGKHGIGRLDLVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDDLMPRYAALIYNGYWWSPERKLLQVLIDESQVNVNGRVRVKLYKGNVMVVGRDSRTDSLFDPDIATFEEDGGAYHQADAAGFIKLNALRMRIAKALRRC
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BORHD
Sequence: MPTINQLIKKPRKSQKEKTASPALQNCPQRRGICTRVMTVTPKKPNSALRKVARVRLSNGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGAKDTLGVNNRKQGRSKYGTKKPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: KDSB_SALTI
Sequence: MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFTDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA1_LACAC
Sequence: MSKNNAVEFRHVSFTYPDTEKPVLNDINFKIRSGSWTALIGHNGSGKSTISKLTNGLLLPDADANSKIIVSGITLNSKTVWNVREKVGIVFQNPDNQFVGATVGDDVAFGLENRGVPRNEMIRIVNRVLSDVGMLDYINAEPANLSGGQKQRVAIAGILAVEPDIIILDESTSMLDPNGRNQILKIIRQLMIDKNLTIISITHDIDEASLADDVIVLNDGKILAQSGPIDIFSKPELLQEIGLDIPFVEKVILKLKETGIKVPQSIKTQDELEQYLCQLNSKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DAAA_STAAS
Sequence: MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGVIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLRNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
What is the function of this protein?
Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine.  The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.  The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism.  This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components (By similarity).
What are the official names of this protein?
D-alanine aminotransferase, D-amino acid aminotransferase, D-amino acid transaminase, DAAT, D-aspartate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: RS17_ALKEH
Sequence: MTENEKVTRNVQGRVVSNKADKTITVLVERRVRHPLYGKYIRRSSKMQAHDEGNECQVGDVVTIEQCRPISKSKAWRLVKVLERAAQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ATPD_THEAB
Sequence: MRYSVIASKYVKALLIVGQKLNKIEKYGEFLSFVKNIYESFATFFNNPIVKPEQKTLVIKQAFEEVFKESPGEAFLNFINIVFENKREKFIPQMQALYKYAAIDIENKILVNVKTAVKLSDQEIKVINDFVEKYVGKTPVIEETIDESLIAGAVIEFAGKMIDVSIKGRMDKIAKEVFFLRKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR14_NANDO
Sequence: MARKSLIQREKKRQRLEQKYHLIRRSSKKEIKKVPSLSEKMEIHGKLQSPPRNSAPTRLHRRCFSTGRPRATYRDFGLSGHILREMLHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DHYS_METVS
Sequence: MSDPKNVIFKESECLEGIFIEGPDFDKDIDLKAVLTDYYEKIGFQATHLGKAVKIWKKIEKLKKEEEMVVFLGYTSNMVSSGLRELISYLVRHKKVDVLVTTAGGIEEDFIKCIKPFVLGDWNLNGAILREKGINRIGNVFVPNDRYIEFETYMTRFFDILSKKQNSENKILSASEFCFELGKFMDENLGNEKEKSIVYHAYKNKIPIFCPAITDGSIGDMLYFYKKNEKDGNLLIDVANDIVKLNDMAIDANKTACIVLGGSLPKHSIINANLFREGTDYAIYITTAIPWDGSLSGAPPEEGVSWGKIQEKADFVEIWADATIVFPMLVYGVFK
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: VIRD2_AGRFC
Sequence: MPDRAQVIIRIVPGGGTKTLQQIINQLEYLSRKGRLELQRSARHLDIPLPPDQIHELARSWVQETGTYDESQPDEERQQELTTHIIVSFPAGTSQVAAYAASREWAAEMFGSGAGGGRYNYLTAFHIDRDHPHLHVVVNRRELLGHGWLKISRRHPQLNYDALRIKMAEISLRHGIALDASRRAERGITERPITYAQYRRLEREQARQIRFEDADLEQSSPQGDHPEFSQPFDTSPFEASAGGPEDMPRPNNRQNESQVHLQEPAGVSNEAGVLVRVALETERLAQPFVSETILADDIGSGSSRVAEGRVESANRTPDIPRAATEAATHTTHDRQRRAKRPHDDDGGPSGAKRVTLEGIAVGPQANAGEQDGSSGPLVRQAGTSRPSPPTATTRASTATDSLSATAHLQQRRGVLSKRPREDDDGEPSERKRERDERSKDGRGGNRR
What is the function of this protein?
Tumor formation by A. tumefaciens involves the transfer and integration of a defined segment (T-DNA) of Ti plasmid DNA into the plant nuclear genome.  The virD operon encodes a site-specific endonuclease that cleaves at a unique site within both 24 bp direct repeats flanking the T-DNA.
What are the official names of this protein?
T-DNA border endonuclease VirD2.
Protein: NUOJ_RHOCA
Sequence: MTVFVFAFYLFAVVAVVAGLMVVLSKNPVHAVLWLILTFLSAAGLFVLMGAEFVAMLLIIVYVGAVAVLFLFVVMMLDIDFAALRGQLVRYAPVGGLIALVMLAQLATGLMVWNTADAANGLRAAPAPEGVENTAALGMILYDRYLYLFQGAGLVLLVAMIGAILLTLRHRTDIKRQNVLAQMHRDPAKALEMVDVKPGQGL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit J, NADH dehydrogenase I subunit J, NDH-1 subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: SUCC_RHOCS
Sequence: MNIHEYQAKSLLKKYGVAVPRGGVAYTLEEARAVAKELGGPVWVVKSQIHAGGRGAGRFKDDPNGKGGVRVVKSIDDVVASTDAMLGKVLVTKQTGPEGKEVKRIYVEEGADIKRELYLSMLLDRATSRITIVASTEGGMEIEEVAHTSPEKIVKVAIDPVQGLQGYHARKVAFALGLEGKQVGACTKFLLGMYKAFTDLDMSLVEVNPLVVTGSGEVLALDAKVNFDDNALYRHHEIEELRDESEEEASETEATRHGLNYVKLDGNIGCMVNGAGLAMATMDIIKLYGGEPANFLDVGGGATKERVTTAFKLILSDPHVEGILVNIFGGIMRCDVIADGVVAAAREVSLHVPLVVRLEGTNVDLGKKILAESGLPILSADNLADAAEKIVKAVKEAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HEMA_I75A1
Sequence: MERVVLLLAMISLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCSLNGVKPLILRDCSVAGWLLGNPMCDEFLTVPEWSYIVEKDNPINGLCYPG
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PCSK4_RAT
Sequence: MRPSQTALWLGLVLSLALLAVGWASARPPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLRLKKEPKVRWFEQQTLRRRVKRSLVVPTDPWFSKQWYMNKEIEQDLNILKVWNQGLTGRGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKPQKKCTIRVVHTPTPILPRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGTLYYCTLLLYGTAEDMTARPQTPQESHCPLSIVAELCLISSKQWWWLYSHTQQPVTKGQDSCHPPTTPARQLDQRLHCLFPAPHAGSASEPLQGLSPLAAILAISLGPWCCPC
What is the function of this protein?
Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.  In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida (By similarity).  Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2 (By similarity).  May also participate in folliculogenesis in the ovaries (By similarity).
What are the official names of this protein?
Proprotein convertase subtilisin/kexin type 4, PC4, KEX2-like endoprotease 3, Neuroendocrine convertase 3, NEC 3, Prohormone convertase 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome membrane.