PharMolix/UniProtQA huggingface dataset:
Protein: CASK_RAT
Sequence: MMRNFIVVMNILALTLPFLAAEVQNPDSNCREKNEVVYDVQRVLYTPVSSVLNRNHYEPIYYHYRTSVPVSPYAYFPVGLKLLLLRSPAQILKWQPMPNFPQPVGVPHPIPNPSFLAIPTNEKHDNTAIPASNTIAPIVSTPVSTTESVVNTVANTEASTVPISTPETATVPVTSPAA
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRI_VIBC3
Sequence: MSKETKLQVEAIKNGTVIDHIPAKVGIKVLKLFDMHNSTQRVTIGLNLPSSALGSKDLLKIENVFISEAQASKLALYAPHATVNQIENYEVVKKLALQLPERINNVFACPNSNCISHNEPVESSFKLSEKNNDIRLKCKYCEKVFARDVVTEIEA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: TRMHL_STAHJ
Sequence: MEDIVIVGRHAVKEAIVSGHTINKIWIQEGIRKQQINDILQNAKEQKLIVQTVPKSKLDNLANAPHQGVAALIAPYEYADFDQFIQSQKDKEGLSTVVILDGLEDPHNLGSILRTADASGVDGVIIPKRRSVALTQTVAKASTGAIQHVPVMRVTNLAKTIDELKEHGYWVAGAEADNATDYRDMAADMPLAIVIGSEGQGMSRLVKDKCDFYIKIPMVGHVNSLNASVAASLMMYEVYRKRHQVGDNA
What are the official names of this protein?
Putative TrmH family tRNA/rRNA methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: CHEV2_HELPY
Sequence: MVRDIDKTTSLHLNNEAQFLCFRLDAEKDAQLYGMNIFKIREIIHYDGEVTEILGGSDGVMLGFLSVRGESIPLVDVKRWLHYNANDPSRDLKECSVKDDHNLVIVCHFSNHSIALKVLKIERIIHKNWTEISAGDKQGINEEGKLSAITRFDEERVVQILDVEKMISDVFPSLKDLDDLTLRCIEAIQSQKLILIAEDSLSALKTLEKIVQTLELRYLAFPNGRELLDYLYEKEHYQQVGVVITDLEMPNISGFEVLKTIKADHRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILEIHEMLKKTLS
What is the function of this protein?
Plays a role in chemotaxis signal transduction system in order to colonize the host stomach.  May act as a phosphate sink to control the flow of phosphate to CheAY.
What are the official names of this protein?
Chemotaxis protein CheV2.
Protein: CA3A1_MOUSE
Sequence: MVPGLQVLLFLTLHLLQNTESSMVHLNSNGYEGVVIAINPSVPEDERLIPSIKEMVTQASTYLFEASQGRVYFRNISILVPMTWKSKPEYLMPKRESYDKADVIVADPHLQHGDDPYTLQYGQCGDRGQYIHFTPNFLLTDNLRIYGPRGRVFVHEWAHLRWGVFDEYNVDQPFYMSRKNTIEATRCSTRITGTNVVHNCERGNCVTRACRRDSKTRLYEPKCTFIPDKIQTAGASIMFMQNLNSVVEFCTEKNHNAEAPNLQNKMCNRRSTWDVIKTSADFQNAPPMRGTEAPPPPTFSLLKSRRRVVCLVLDKSGSMDKEDRLIRMNQAAELYLTQIVEKESMVGLVTFDSAAHIQNYLIKITSSSDYQKITANLPQQASGGTSICHGLQAGFQAITSSDQSTSGSEIVLLTDGEDNGIRSCFEAVSRSGAIIHTIALGPSAARELETLSDMTGGLRFYANKDLNSLIDAFSRISSTSGSVSQQALQLESKAFDVRAGAWINGTVPLDSTVGNDTFFVITWMVKKPEIILQDPKGKKYTTSDFQDDKLNIRSARLQIPGTAETGTWTYSITGTKSQLITMTVTTRARSPTMEPLLATAHMSQSTAQYPSRMIVYARVSQGFLPVLGANVTALIEAEHGHQVTLELWDNGAGADTVKNDGIYTRYFTDYHGNGRYSLKVRVQAQRNKTRLSLRQKNKSLYIPGYVENGKIVLNPPRPDVQEEAIEATVEDFNRVTSGGSFTVSGAPPDGDHARVFPPSKVTDLEAEFIGDYIHLTWTAPGKVLDNGRAHRYIIRMSQHPLDLQEDFNNATLVNASSLIPKEAGSKETFKFKPETFKIANGIQLYIAIQADNEASLTSEVSNIAQAVKLTSLEDSISALGDDISAISMTIWGLTVIFNSILN
What is the function of this protein?
Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner.
What are the official names of this protein?
Calcium-activated chloride channel regulator 3A-1.
What is the protein family that this protein belongs to?
Belongs to the CLCR family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEA_AZOPC
Sequence: MRLSKFKFHLPQELIALFPSVDRDESRLMVVYHKTGRVEHVIFKDIIQYFNEKDTFIFNDTSVIPARLNGNKEKTGARVEVFLLRELDPIQRIWDVLVDPARKIRIGNKLYFENEDSDTIVAEIIDNTTSRGRIIRFLYDGPYESFKKILYNLGNMPIPDYLDRKVTKEDRERYQTIYAKNEGAVVAPAAGLHFSHELMKRLELKGCELTFITVHSGMGNFRAIDVEDLFKYKSESERIVINTETATKINQAKQNRKQICAVGTSVLRTIEDRENVVTSQGYLNPFTGWTNKFIFPPYNFITSTSLITGFHLPLSSMLLQVAAFGGFDLIMDVYKQAIEAKYRFGVYGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_MYRV9
Sequence: MFDRQYPTVHDLYIPFPVFQSRLEQPFDTTVTSIRELRTISSQSTVYGYDLTVNDPLYYDLEPLLGNSISLTLDPKLTDSERLDAVYLDINNRLANCHGDLLRKFSATSYSIDTSVIPYVFLPMYRYLLHIMTGSAFNSLFRQMIVNVDANCANADESLLTSAQHLFALLNKINPSRQLPAPLRHILINATIADVPYDMQGKFVPYNVVFLPTSNESLRDATIARIREPAGYHPRPSIVVPHYFVFRSTTDALCRFMYLAKRTFLHVNDKTATHTSVRRCELLRLNFPLDQSFAQLSLLVQLQLPLSTLSIQRLPHLSTTVNQLITLASSSYSEQAIINLLRVNWNVIGYIELSTLGEPSLPAIRVYDFTSSMNTRSVTQGPNVQIRTRSNAIDVHVREFIRFGRYLPLEIPKCRVPRLVSLQVINYSLNHLLSVTPWPDQYDVTRHRPERIIENSVKRTIQYQEYDPSVGTWATSSDMTNYTHIPSDSYYHQFIVTCLRSFCGLRDLPRENSARYPYVVLLYGLALGHEIAPSRMGLTYAMTSHMISYVLSTITTGIDVAPSEIISRFKLFLIDVPFADTIIHDLRKVTPNVNVHSTSIFTSNERGDARILTGWVVIRIAVSRFEQQKRSFEYMSYFNDILRFCDGGIIHFDIPDATFLMHVVTSLQCTPNRRVKVLSYFASQSPFSLTLHFYRDTTDPLLPVANIGHWVTRHQMKRYAYTDRDSTIPLRHEVIPALSTVMSRMTAEYSFVCQKSDLPVCLSALSTISNYARVATWTDYRGIAHWSGSAVIDPLRLLDSSRTGVLATNVPIEPLIAPSHGVPRLERSTYRVVDAFHLCSLIGPIFIQREFNIWTASRTSERTRHVIDVGGRDGAFRGLFPHAMYTVIDPAPAPQHMISNYISEPWDFNDFQGSLDRIMDTLGIIDPQDVFLVFSHVFISALNRPAAHVNALEQLGALQCSSVVSTQTSGSSASTLYSSYVNHNPFLEIRMENAAYLTRTYPSPYPLPTRAEMNEAILNNARSRLHQTSAAEILDLAMRFGYAPSYEAIVTLPALCDQHVVYAIQ
What is the function of this protein?
Outer capsid protein involved in mRNA capping.  Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities (By similarity).
What are the official names of this protein?
Outer capsid protein VP3.
What are the subcellular locations of this protein?
Virion.
Protein: RL21_CLOD6
Sequence: MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKDGELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SYDND_RUEST
Sequence: MHAFRSHTCAELNKSHVGETVRLSGWVHRVRDHGGLLFIDLRDHYGVTQVMADPDSPVFAEIEKVRSEWCIRIDGEVKARDESLVNAKIPTGEIEVFIRDIEVLGKSEELPLMVFGEQEYPEETRLRYRYLDLRREKMQRNMVLRSNMIRSIRNRMWDQGFNEYQTPIITASSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLMMVSGFDKYFQIAPCFRDEDPRADRSPTDFYQLDMEMSFVTQQDVFDTIAPVIAGVFEEFGQGRKVDAPNEWPQISYKDAALWYGSDKPDLRNPIKMQVVSEHFRGSGFAIFAKLLEQEGTEIRAIPAPTGGSRKFCDRMNAFAQKEGLPGMGYIFWREGADGMEAAGPLAKNIGPERTEAIRQQLGLGVGDAAFFLGGKPKTFEAVAGRARNVIGEELNLTDKDRFAFAWIVDFPIYEKDEETGKIDFEHNPFSMPQGGMDALNGDPLDVRGNQYDLACNGYELVSGAIRNHKPEIMFKAFEIAGYGKEEVEKRFGGMVNAFQYGAPPHGGCAAGIDRMVMLLADEANIREVIMFPMNQRAEDLMMAAPSEPMSEQLMELGLRVIPQDD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_METM6
Sequence: MKIIGILGIQGDIEEHEDAVKKINCIPKRIRTVNDLEGIDALIIPGGESTTIGKLMVSYGFIDKIRNLKIPILGTCAGMVLLSKGTGKKQPLLEMLNVTIKRNAYGSQKDSFEKEIELGGKTIHAVFIRAPQVGEILSNDVEILSKDDGNIVGVKQGNIMAISFHPELSDDGIIAYEYFLKNFVEKD
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DENR_DROME
Sequence: MTNEDVGTNSVADRLQLGPREGVTYPIQMKYCGHCTMPIEYCEYYPEYEKCKEWLELHMPDDFERLKIEEEAAAADGTDDDKKRQKRGGKGLLRVKKKEDVPKRICVSRAARGKKKSVTVVTGLSTFDIDLKVAAKFFGTKFACGSSVTGDDEIVIQGDVKDDLFDVIPEKWAEIDEDVIEDLGDQKRT
What is the function of this protein?
Regulates translation as part of a complex with MCTS1.  Specifically required for translational re-initiation in mRNAs containing upstream open reading frames (uORFs).  Not required for standard translational initiation.  Regulates expression of a subset of gene products including mbc, InR and EcR.
What are the official names of this protein?
Density-regulated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: NAPA_LARHH
Sequence: MTLTRRDFIKANAAAAAATAAAVNLPLVPSMAQAATTDPATAGADIKWDKAACRFCGTGCSVLVGTKGGRVVATQGDPDAPVNRGLNCIKGYFLSKIMYGEDRLTKPLLRMKNGKFDKNGEFTPVTWKQAFDVMEEKFKTAMKAGGPEAVAMFGSGQWTIWEGYAAAKFMKAGLRSNNLDPNARHCMASAVVGFMRTFNMDEPMGCYDDIEKADAFVLWGSNMAEMHPILWSRITDRRLTHPDCQVHVLSTYEHRSFELADNKLVFGPQTDLAILNYIANHIIQTGAVNKDFIQKYCAFMKGDTDIGYGLRPTHPKQKAAKNPDSGKMDPITFEQFAAFVKPYTLEYTARTSCVPAERLKRLAELYADPKKKVVSFWTMGFNQHTRGTWANNLVYNIHLLTGKISTPGCGPFSLTGQPSACGTAREVGTFAHRLPADLVVMNPEHRKIAENIWKLPEGTIPPKMGLHAVAMQRALKDSKLKVYWQQCNNNMQAGPNINEEMYPGWRNPETFIIVSDPYPTVSAMAADLILPTAMWVEKEGAYGNAERRTQFWRQQVNAPGEAKSDLWQVVEFSKRFKVEEVWPAELVAKKPEYRGKTLYDVLFANGQVNKYKLDDMARQHGTAYHNEEARHVGFYLQKGLFEEYAAFGRGHGHDLALFDTYHKARGLRWPVVDGKETLWRYREGFDPYVKKGEGVRFYGQKDGRARIIALPFEPAAEVPDREYNMWLCTGRVLEHWHTGSMTRRVPELYRAVPDAQVFMHPADAELRGLKRGQQVKVISRRGEITLTLETRGRNKPPQGLVFIPFFDEGRLVNKLTLDATCPLSKETDYKKCAVKVVRA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL11_ALKEH
Sequence: MAKKVSAYIKLQVGAGKANPSPPVGPALGQHGVNIMEFCKAFNAQTQEMEAGLPVPVVITVYNDRSFTFITKTPPAAVLLRKAAGIQKGSGEPNTKKVGTVTREQLEEIAKTKEPDLNAADLDAAVRSIAGTARSMGLDVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SYP_VIBCM
Sequence: MRTSNYLLSTLKETPNDAEVVSHKLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAIETLMPVVQPFELWEETGRSEKMGPELLRFTDRHERPFVLSPTAEEVITALVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKAGLEKSYEAMHVAYCKAFDRMGLDYRPVLADTGAIGGNGSHEFHVLAESGEDLIAFSTESDYAANIEKAEAVAPAIERPAPTQAMTLVDTPNAKTIAELVEQHGLPIEKTVKTLFVKASDEIDAPIVALIIRGDHELNEIKAEKLAEVASPLEMASEEEIRALIGAGPGSLGPVGLKLPFIVDRTVAVMNDFGAGANIDGKHYFGINWGRDVELGKVEDLRNVVEGDPSPCGKGTLMLKRGIEVGHIFQLGTNYSEKMNCGVLDSNGKNVILEMGCYGIGVSRVVAAAIEQNHDDYGIIWPDAIAPFQVAIVPMNMHKSERVQQAAEKLYAELTAAGIEVLFDDRKERPGVMFSDMELIGVPHTIIIGDRSMDEGHFEYKNRRQGEKEAVAMESIIDFIQAKLA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXY_YERPS
Sequence: MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLDKALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: MURG_BRUSU
Sequence: MDNLANQGVIVLAAGGTGGHLFPAEALAHELRARGWDVHLATDARAQRFVGAFAQDHVHVIRSATIAGRNPVALLKTFWSLWQGNLDSRKLFRRLKPKLVVGFGGYPTLPPLYAASNMGIPTLIHEQNAVMGRANKGLAGRVKAIAGGFLPENSGAYAAKTVITGNPVRPPVLVAAATPYTPAGKDDRFRLLVFGGSQGAQFFSQAIPAAVALLPEHERARLLITQQARKEDEASARQAYEKLGVPADVAPFFNDMPARMADAHFVIARSGASTVSEITVIGRPAMLVPFPHALDHDQAANAAALAAAGGAEVVRQADLSPQRLAEMLQSAMNEPERLEQQAKAAKSVGKPDAARLLADLAEAIVSGKTVQEFKEGNRP
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CIN8_ASHGO
Sequence: MPDHEVQTRKSRMLDDAQEELNITVAVRCRGRNEREIKAKSSVVVTVPDVTGSNEVSINTTDEVGIAAKMNSRTYTVDKVFGPSADQSLIFKEIAEPLFDDFMKGYNCTVLVYGMTSTGKTYTMTGDEKLYDGQLSDSAGIIPRIMFKLFDALEATDSDFLVKCSYIELYNEELKDLLDESHDSSKRLRIFDSSSMNHSSRASSQSNSPREPEVAHNGFSRRRQRPPPVKANRMSATKQQLSESGSGIYVQNVQEFHIINAREGINVLQKGLKHRQVASTKMNDFSSRSHTIFTIMLYKNCDGELFRVSKMNLVDLAGSENISRSGAQNQRAKEAGSINQSLLTLGRVINSLADKSIHIPFRESKLTRLLQDSLGGNTKTALIATISPAKINADETSSTLEYAAKAKNIKNRPQLGALMMKDILVKNISSELAKIKSDFLSTKSKDGIYMSHEHYQEIVNDLENCQTEIQESKRQIESLTSQNNLLLKDKKASQEVTELQNSKIKKLQSTIEYLYDKIERQHHNETELATTIHKLKEALHTMQGSLKSYETHELRLQNDIKEVLYQGITSYRESMNQHLEKVKVSMLDKNLSIKENINNITTIFDDTLKSVEANGSDMCDTLVKLIKETPSMYLKEFNETVSSLKSELSSYSNALTNKLTEISEENNHLREYLDQHLFKNSTQEVLDLRMESVYQKVKNDSDQLLSKLVSMVGAHVEESRTLMVNSMKDTVNEIIDNERSLFQPIRDRWIASCDNINQCDASHQNFEAKSTSGLDKLKELSDASLKSSEDAVNKAKHRTDSFHDFVQKLCCDQSLKKQMHDISDKHRMLEDHFDDNVKYFKESSKGFEDMDCSIKKIIHEMSPEVGDIKSVETLMERINARTFSPVRPTGKTPSRQVLKNAITSKASSRSMSPIKTLDTNVRIISPVKRGTIEFGAEGPPTKKVR
What is the function of this protein?
Required for assembly of the mitotic spindle.  Interacts with spindle microtubules to produce an outwardly directed force acting upon the poles.  Following spindle assembly, CIN8 and KIP1 apparently act to oppose a force that draws separated poles back together.  This force seems to be mediated by KAR3 (By similarity).
What are the official names of this protein?
Kinesin-like protein CIN8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Note=Spindle microtubules that lie between the poles.
Protein: DPOD1_RAT
Sequence: MDGKRRQAPSSGVPPKRACKGLWDEDEPSQFEENLALLEEIEAENRLQEAEEELQLPPEGIVGGQFSTADIDPRWLRPTPLALDPSTEPLIFQQLEIDHYVGTSPPLPEGPPASRNSVPILRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGAEHLSELQRELNAAISRDQRGGKELSGPAVLAIELCSRESMFGYHGHGPSPFLRITLALPRLMAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKYVRRAEKKATLCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWATFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQMDMLQVLLREYKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLKDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMREGLLMPVVKTEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLGLKPDEFIKTPTGDEFVKASVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSPNSVYGFTGAQVGKLPCLEISQSVTGFGRQMIEKTKQLVETKYTLENGYDANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSRSDAHDRMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPNLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLEQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNSCIGCRSVIDHQGAVCKFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFGPPGPEAW
What is the function of this protein?
As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair.  Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities.  Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity.  Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity.  Most notably, expresses higher proofreading activity in the context of Pol-delta3 compared with that of Pol-delta4.  Although both Pol-delta3 and Pol-delta4 process Okazaki fragments in vitro, Pol-delta3 may be better suited to fulfill this task, exhibiting near-absence of strand displacement activity compared to Pol-delta4 and stalling on encounter with the 5'-blocking oligonucleotides.  Pol-delta3 idling process may avoid the formation of a gap, while maintaining a nick that can be readily ligated.  Along with DNA polymerase kappa, DNA polymerase delta carries out approximately half of nucleotide excision repair (NER) synthesis following UV irradiation.  Under conditions of DNA replication stress, in the presence of POLD3 and POLD4, may catalyze the repair of broken replication forks through break-induced replication (BIR).  Involved in the translesion synthesis (TLS) of templates carrying O6-methylguanine, 8oxoG or abasic sites.
What are the official names of this protein?
DNA polymerase delta catalytic subunit, 3'-5' exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PCNA and POLD3 at S phase replication sites. After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex.
Protein: PUR7_VIBPA
Sequence: MSLANQVLAVNDDLPIRTHKPVHSGKVRSVYWLTEEDSARLIKEKGYDVAPDAPLAIMVISDRISAFDCIWHGEGGLKGVPGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQKAKPVKIEAICRKYITGSMWRAYANGEREFCGIQLPEGLEKDKALPNLLMTPSTKGILKGIPGVPEADDVNITRQNIVDNYEAFNFSSAEDIAQYEKLLKEGFNVISQALEGIDQIFVDTKFEFGYVHDAAGNEKLIYMDEVGTPDSSRIWDAKEYQAGNIVENSKEGFRQFLLNHFPDPDILLNKERMPEREALARDNDLPVESLMDISRTYIGIAEKITGKPITLSENPKAEIIEILSKEYGLID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: YH1A_YEAST
Sequence: MPQVQSWFPVQKQPTLAVTFTPLPQLSHAHLPLPPSHLVTKTDAMFQHQLLPTQLQPFPPNHTPLLLLLTVTTMAVTPRLSLLNVLKKLQQPPFLQNHTLLLPLLTVTTTAVTPRLSLPRLPNKHHWPLAQSPSLLLQLLILLLPAPSLVLSFNPKVWLLV
What are the official names of this protein?
Putative uncharacterized protein YHR214W-A.
Protein: Y5785_FRAAA
Sequence: MAMRAKDALGRFGEEVASRHLAAGGAAILDRNWRCREGELDLVLRDGADLVFCEVKTRSGTRFGSAAEAVVGRKAARIRRLAARWLAEHPHAPSSVRFDVVLVSRPPVGPVRVEHLRGAF
What are the official names of this protein?
UPF0102 protein FRAAL5785.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NUP82_CHATD
Sequence: MPKIKSFAPAWLNEPAPGHKLFAPAADDGTATVPLAYGKKIKPGPRRTIARRGTEIFVACGKQIRWGDLAQLKESWESRPSRSSVGPTSTKKDSSDFDDGAATAGYRIIKTPVADDIRQLVMSPNQDFLAVLTSHTVHICILPDSSHLHIQDTTPFKPKFWTLGPTTHVTSRSAVVSAVWHPLGVNGHALVTVTEDAIVRVWELSTADRWTFDAPTLAIDLKKLADATYLDQDFGVSTSATNKGFSPDAFDMEVAAACFPTRDSGGWAPMTLWLAMTSGDVYALCPLLPQRWTPPPTLIPSLSASIVAKVAAAEDNPESTPEERLVAQQQLEWMSEIDNQEPKLVEEATGEATIEVYTRPSRPGLVPKLQGPFDFDLNPEDEQDDEVELKDIYVIGEKPRVADLMRGEEEELEMMKEDQHNGLSLNIICLLSTSGQVKICLDIDGVEAQWLPPRSKNKRLFAPPPEPPSLLTFQTFDTLKPAEVTPDGWPMFSEDATSPYSFYVTHPAGITYISLTPWVFRLESELQSDSEAGTEFRIDLLAKGQGSERDRIFTQTRTQSPLAAATSIDDPDLGYFILSATQTDPIALFFETPERPVVPKETSVVIPEHVEERPPSPYWEPRPLFHPAEALDKPSAVPAWIDNLRTGRRRPLLTQELRLSMATLEVFHDGHKVVSTEVSDINDAVAELFRKCEALQGELRDQIKKVNEVKNRIHTITGDDLSDDPPVSEDQLIKQRIRVARERQEELANRMERLRKKFGRTTTRELSDKEKAWIEEVQNMATSILGPEAGQGALATTPNLAKQPWKRLEEIKTLRNALMAEAEQLQKVGDDTEESTPASQMPSLKIPSEIRKAKMAQVMSLLERESALVDAVKARIERLSIG
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
What are the official names of this protein?
Nucleoporin NUP82, Nuclear pore protein NUP82.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYC2_RHOGL
Sequence: GSAPPGDPVEGKHLFHTICILCHTDIKGRNKVGPSLYGVVGRHSGIEPGYNYSEANIKSGIVWTPDVLFKYIEHPQKIVPGTKMGYPGQPDPQKRADIIAYLETLK
What are the official names of this protein?
Cytochrome c2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: FABH_STRA3
Sequence: MVFAKISQLAHYAPSQIIKNEDLSLIMDTSDDWISSRTGIKQRHISKNETTADLANKVAEQLIEKSGYSASQIDFIIVATMTPDSMMPSTAARVQAHIGASNAFAFDLSAACSGFVFALSTAEKLISSGSYQKGLVIGAETVSKVLDWTDRGTAVLFGDGAGGVLLEASKEKHFLAESLNTDGSRQGLQSSQVGLNSPFSDEVLDDKFLKMDGRAIFDFAIKEVSKSINHLIETSYLEKEDIDYLFLHQANRRILDKMSRKIDIARDKFPENMMDYGNTSAASIPILLSESYENGLLKLDGNQTILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_BORPE
Sequence: MANTSHSSQDQFANKAQAWSARFSEPVSDLVKRYTASVDFDKRMARHDIRGSLAHADMLAAQGIISAQDLADIQRGMQQILSEIDAGSFQWLLDLEDVHLNIEKRLVELVGDAGKRLHTGRSRNDQVATDIRLWLRDEIDTLVDLLRQLRHALATVALENAATIMPGFTHLQVAQPVTFGHHLLAYAEMFGRDAERLADCRRRVNRLPLGAAALAGTSYPIDRERVARTLGFDGVCRNSLDAVSDRDFGIEFCAAGALIMTHISRLSEELVLWMSPRVGFIDLADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLVALLTLMKGQPLAYNKDNQEDKEGLFDTADTLRDTLTIFADMAGGIKVKADNMRAAALQGFATATDLADYLVKRGLPFRDAHEIVAHAVRDCEQRGCDLADLSLADLQAYHPSIGEDIHQVLTLEGSVAARKHIGGTAPERVREEAQRVLAETAGA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.