PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_KOCRD
Sequence: MSNDSSLGLMQIGLATADQIRGWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRYKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITSVDEQARHDDLPNLQAAIDREKKQLEDTRDADINAIARDLENDLARVEEEGGKAAEKRKLRDSADRQMANVRKRADREIDYLEKVWDRFKNLKVNDLEGDEALYRQMVDRYGMYFEGSMGAESIKKRLETFDLAAEAEALRETIATGKGQRKTRALKRLKVVNAFLTTDNSPLGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDSLFDNGRRGRPVTGPGNRALKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKQMALELFKPFVMKRLVDLNHAQNIKSAKRMVERYRPQVWDVLEEVITEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCGAFNADFDGDQMAVHLPLSPEAQAEARVLMLSSNNILKPSDGKPIALPSQDMIIGLYHLTTVREGWAGEGNTYSSVAEAIMANDSGELHLNAKCKIRLEDFVPYAGWEAPEGWEPGQPAVVETTLGRVLFNETLPEDYPWDENVADKKHLSALVNDLAERYPMTRVAKTLDNLKDAGFHWASRSGVTVAISDIATPPEKPAIMEGYEAQAARIQGQYDKGLIDDDERRSELIDIWSKATDEVAQAMRDNLEPTNTINRMVSSGARGNWMQVRQIAGIRGLVANPKGEIMPRPIKSSYREGLSVLEYFIATHGARKGLADTALRTANSGYLTRRLVDVSQDVIVRESDCQTVRGLTLPLSDITDTGVRTLSEDVENTVHGRVLASAVADENGEVLAEAGADMSDAMIEKLYAAGVDQVRVRSVLTCESAVGVCAACYGRSLATNQLVDIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVASSDGDITQGLPRIQELFEARTPKGVAPISEVAGRIRIEDTDKSLKIVVVPDNGDEEFAYPVLRRAKLLVADGDHVDVGQQLVTGAVDPKEVLRIRGPREAQKHLVDEVQGVYRSQGVGIHDKHVEVIVRQMLRRVTIIESGDTSLLPGELVDNVRFLEANRGAVAEGKRPAAGRPELMGITKASLATDSWLSAASFQETTRVLTQAAMEGKSDPLLGLKENVIIGKLIPAGTGLDRYNSVDVEPTEEAKAQMFTDPSAFADFSYAEENAGGLGSEFQAIPLDDYDFGGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NUON_BUCAI
Sequence: MIINLQQLTALLPLLIIMLTVITVILSISYNRNHFFVAVFSILGLIFALCSLYFLIEIIPINVSILFHFNSNAILYIGMILISSICTCIFSYPWLLKYPFNKEEFYLLVIISTLGAISLTISHHMASFFINIELISLPMFGLIAYSRYQKYSLESSLKYIILSGVSSSFLLFGIAWVYSISGGLDFLSIHKSFNFASEKEILVVLFGISMILLSLFFKLSIVPFHLWTPDIYQGSPTSVLSFFSTAGKISVFSVLLNFLSYFSNSDNKVIYFILSLIIILSILVGNLMALFQKDIKRFLGYTSISQIGYLLIVLLVSHKNYSFSLEASAIYLCGYLFSNIACLGIVNLISTSHINNNASSINSYRGLFWSHPLLSSVLTLVLISSAGIPMTLGFIGKFYILSIVMIEHLWLIGFAFLIGSLLGLYCYLRIILNLYLHPSKLFKRDLNIPLNWVYTPSGIVICISGIILLALGIYPNPLIGLIKCTI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPB7_MOUSE
Sequence: MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element.  The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft.  The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.  Binds RNA (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB7, RNA polymerase II subunit B7, DNA-directed RNA polymerase II subunit G.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
Protein: SECB_ACISJ
Sequence: MAEETPVFQIQRVYLKDLSLEQPNSPAILLEQEQPSVDIQLGVEATPVVEGIFEVAVTATVQTKIKDKTVFLVEAKQAGIFEIRNVPEDQMGAIIGIACPQIIYPYLRGNVADTVTRAGFPPVHLAEINFQAMYEQQQAAAAEAATSTAQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL1B_LAMGL
Sequence: MATVPEPTSEMMAYYSDNDNDLLFEADGPKQRKCCVQPPDLGSLGDEGIQLQISHQLYNKSFRQVVSLIVAMEKLSKCTYSQYFQDDDLRNIFSLIFEEEPVTFETCADDFVCDAVVQSLYCKLQDKEQKSMVLASPYVLQALHLLAQDMSREVVFCMSFVQGDENNSKTPVVLGLKEKNLYLSCVMKGDKPTLQLEALDPKSYPRKNMEKRFVFYKTEIKDRVEFESALYPNWYISTSTAEQRPVFLGQSRGGQDITDFTMETLSP
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: YSV5_CAEEL
Sequence: MEKSVSGPNIFNMKLLLLLLILTISFCYAFNNETLKVRLNVPFFKFFSKNGHHVVDEEIPKITIPEIRLPFSSSIGHGVVRTDDLKIEKFSSPKIDFKLSKTGINWWTTGGAIKLSGRWHAKFTEVITIRDKGWLNAYATGIQMNISAAAYQLDGQPQVKIGDCTVQIQKLDVEIGGSVLSWLVNLFETPFSKLVKKVINAQACSAAKGILIEEANRFLHSLPSHVDVGANFYVDYFLTQNPHATSEFTEFDLAADIVYGKSLCHPINIGNWTDASSTPGMLTSWISVSIPNCLIHSAHQNQLVKLLVSKDIPVVEPYLRTSCGFLGLCIGKFFKKLRNEYPNNHVDLFFHTYSTPYFVMSEKEGVMLNMSLAVDLFINPYAKTKQNILARLVVDTFSTVEPFLNHTRIHGRLQNSTITARVDFSNIGDIPKAFLSAFSSILSMTAREAVRSVLGVGIPIPSYDNVTLADSSTIEVFDQFLRANIDFEYK
What are the official names of this protein?
Uncharacterized protein T19C3.5.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Protein: SIR1_YEAS7
Sequence: MLQINSRLAVIDGWLVDTVKRKPINFRSPEVRLLLPNDDDYKKLSQQNLVDWTRLKKDSNSVLVGVKSMELFKHIKLVLREFFLLEDGRIILKRIRSKLRYKVVKKLTCKCCRLNLPKWGTVYIHPMLKDKEKPLAGVCEFSLDVNPDREYPLIEINVSHQYIIIEGFLLYLNERRLYRWNDNNLRSQVGLTKWAHLRKTYNPVSLDILYSLNSNFYFVKDDLLFQLLGKRVFVKFCKVMENGKCGKAPLWYRVKRTTTAKATHIAYAISNSTAPDSFKSKNNDYRFIVREKPIVENTISNLDYSDIKKQQFTEAEVVKRKISADISQIENVHTQFNSQKEKNNIRVNKVSSEVLDQISKFPVSRVTLLLISAGQDKNYIELVEELARRLEKICIEKTTQSLEEIRDTFQANPEMQARFDKEYYQSIEEYKITLELIKEDLLITLIKQMENMWAAEKKFSTEEEYVSPRFLVADGFLIDLAEEKPINPKDPRLLTLLKDHQRAMIDQMNLVKWNDFKKYQDPIPLKAKTLFKFCKQIKKKFLRGADFKLHTLPTEANLKYEPERMTVSCSCVPILLDDQTVQYLYDDSIIPEFEATSSYATKQSKCGGKMSLQMEPDLLFQEAIRRMRHLTAYDVLRRNYIAAFEELYMGNCND
What is the function of this protein?
Involved in the establishment, but not the maintenance, of heterochromatic silencing at the cryptic mating-type loci HMR and HML.  Is recruited by interacting with the ORC1 subunit of the origin recognition complex (ORC), which binds to HML-I or HMR-E silencers, DNA elements that direct the formation of silent chromatin at the mating-type loci.  Establishes transcriptional silencing by recruiting the three other SIR proteins, SIR2, SIR3, and SIR4, that function directly in silenced chromatin and establish repression.  Also found in centromeric chromatin.  Binds to and helps retain CAC1, a subunit of chromatin assembly factor I (CAF-I) at centromeric loci independent on the other SIR proteins (By similarity).
What are the official names of this protein?
Regulatory protein SIR1, Heterochromatin protein SIR1, Silent information regulator 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associated primarily with the HMR-E silencer at the HMR locus.
Protein: MDTI_ECO55
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLX1_MALGO
Sequence: MRISSVVEHRTPRVYVCYCLRSLSRPNQTYIGSTPDPIRRLRQHNGLVKQGAFYTRMARPWTMDVVVYGFPSKLAALQFEWSWQKPHASRHLRVMHDDGTRPNKSSATAAVYAGRSSKPLFPATRSSAPSSAASHDSGLNLRKKNRRVRMRSSTVPEYKFLVLRALLASEPFCFWHLHVGFYSEYAYGVWQFMDRANPTRYSVSRITRRPLPPSYPPVACDFRGVQGTNTPLAPPQDATAHTLRTSYPVLPEATTLSAAQKKKRSTSASCAPENEHMWAEEIPHARDAETLGLTWEQLEHAPTIARMEVPDGLMQASSAARGRSRRLRSHTSFLEALDQDASALEAHLVHASRKDMSSSICGLCGGHINRHVPLSYTHCPHACDAVFHLTCLARYSLEQETRAHARTFCLPTSAWCPMCQRPPVPWPEIVRRVFRRAELKVSM
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1934_MACCJ
Sequence: MRGGGNMQQMMKQMQKMQKKMAEEQEKLKEERIEGTAGGGMVTVVVSGHKEVLDVIIKEEVVDPEDIEMLQDLVLAATNDALTKADDVTAQRLGQHTKGLNIPGMM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein MCCL_1934.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: S12A8_HUMAN
Sequence: MTQMSQVQELFHEAAQQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLREGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKSKKATKQTLQDSFLLDLKSPPSFPVEISDRLPAASWEGQESCWNKQTSKSEGTQPEGTYGEQLVPELCNQSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSCRSLRSPQEQIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLMPHY
What is the function of this protein?
Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation.
What are the official names of this protein?
Solute carrier family 12 member 8, Cation-chloride cotransporter 9.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SCD1_ARATH
Sequence: MGRIFEYFVVCGLGPEMRTVDGDLGFHGMQTFYLPALLDQFPPTDQSPYPAPPPQLPTCVLPAGVEFHSSGFVSSDPASFPRSYPIVLTEGDGSKIFVSCIAFRDRVCEDIIEAYRLPPNTYADKCICLVSHAPNFRVLRNSLEEIFVLCFSSEGSCKPLWDIIAYMVSNVPLPTPGKDRVLFAVENCLLSVEAPPEDSLPQADISLQPLVQCLDVDNLIKLFTSVLVERRILIRSNKYSLLTLVSESICHLIYPFRWLQVYIPLLFFSGVDYIDAPTPYMMGLHSDVDTSNLAMDGVVVVDLDINQITTSEEIPQIPEPEFSTLRNDILKLLHPNVVAIDQLKGFGNSVEQCPKSLSKPWGEDHDLQLRVIFLKCFASILGGYRNFIENKVFSTDAFLKRRSRSTNQPPEPMLVQFLGSFAFLDYLERRLSSDEKSTNLLEKLQDAVGRGQDAMSILPKSSMEPEIITIAEPEVEESATRYTYDRFPASVRSEEQEEKRKQILAAASGALESNGRHPPSSPPGKNTKEDNFSSMERAAERERMVLDIQVKLQGLWLRLLKLGSDEDPLSSFEYGTILALIESDAEGIGGSGFIECIREHLYSGWHGQLSEEQFIAVKELLKMAVGRAASRSDLSTVRDALEVSAEMFKKDANNVSDYVQRHLISIPIWEELRFWEGYFEYLMEQPANESVNYATLVTARLIIVASHMAGLGLPDTEAWNMIETIAEKQKLGYKLLIKLRGFLSHVQQLRVGYWGASSFKQQAISAGLPSPRPKDVSVSDETQQPSEASGRSWVQSMFSRDTASRANSFSRVRKWVSDNASSDITAAAQKKIQTNVRVLKGHGGAVTALHSVTRREVCDLVGDREDAGFFISGSTDCLVKIWDPSLRGSELRATLKGHTGTVRAISSDRGKIVSGSDDLSVIVWDKQTTQLLEELKGHDSQVSCVKMLSGERVLTAAHDGTVKMWDVRTDMCVATVGRCSSAILSLEYDDSTGILAAAGRDTVANIWDIRSGKQMHKLKGHTKWIRSIRMVEDTLITGSDDWTARVWSVSRGSCDAVLACHAGPVQSVEYSPFDKGIITGSADGLLRFWENDEGGIKCVKNITLHSSSILSINAGENWLGIGAADNSMSLFHRPSNAGTKVSGWQLYRVPQRTAAVVRCVASDLERKRICSGGRNGVLRLWDATINI
What is the function of this protein?
Involved in growth and development through its role in cytokinesis and polarized cell expansion (PubMed:12874123).  Required for plasma membrane internalization.  May function in clathrin-mediated membrane trafficking, including plasma membrane endocytosis, essential to both cytokinesis and cell expansion (PubMed:24179130).  Acts as a negative regulator of basal resistance against bacteria (PubMed:20472560).
What are the official names of this protein?
DENN domain and WD repeat-containing protein SCD1, Protein STOMATAL CYTOKINESIS DEFECTIVE 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin at the plasma membrane.
Protein: IL12A_MACMU
Sequence: MCPARSLLLVATLVLLDYLSLARNLSVATPGPEMFPCLHHSQNLLKAASNTLQKARQILEFYPCTSEEIDHEDITKDKTSTVEACLPLELIKNESCLNSRETSFITNGSCLASRKTSFMMALCLRSIYEDLKMYQVEFKTMNAKLLRDPKRQIFLDQNILGVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_CORK4
Sequence: MKKNIHPDYHPVVFKDASTGHQFLTRSTATSDRTVEWEDGNEYPLIVVDVTSESHPFWTGAQRVMDTAGRVEKFQRRYGNRLRRAKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PTH_METC4
Sequence: MRLIVGLGNPGARYARNRHNIGFMAVDEIARVHRAAPFRRRFQGEAAEVMLGSERAILLKPQTFMNESGRSVGEAQRFFKIPLADVIVLHDELDLAPAKLRVKLGGGNAGHNGLRSITALCGNEYRRVRLGIGHPGDKALVHAYVLNDFAKSEEPWVEDLCRATADHAPLLAAGEDASFQNKVHLAMAGRGWETVKTPAEAGKAKARDAN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_OENOB
Sequence: MPRKAYTKQQEVLPDPIYNSKLVSRLINKLMLDGKRGTASSILYKAFDRIQSETGNDPVEVFQQAMENVMPVLEVKARRVGGSNYQVPIEVRPERRTTLGLRWIVQYARLRSERTMEERLSKEIMDAANGTGASVKKRDDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RPO5_METTP
Sequence: MKRFAVQDHELVPEHILLTPEEAQQVLMQYGVEARHLPKIHVTDPVAKEIGAKVGDIIKIKRKSPTAKESIFYRLVID
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_OSTTA
Sequence: MALRFYKAYTPGTRNRSVADCSGLTKTRPEKSLTRSMHRAKGRNNRGVITCRHRGGGHKRLYRQIDFRRNKYDMAATVKTIEYDPNRNARIALVEYQDGEKRYILHPNGLEIGDSIIASETAVNAVGNSLPLMAMPLGVQVHNIEMHPKKGGQLVRSAGAVAQLVAKEGEYVTLRLPSGEVRLISNKCWATIGQVGNMEAMNLSLGKAGRSRWLGRRPTVRGSVMNAVDHPHGGGEGRCPVGHAQPRTPWGKPALGVKTRTRKKYSDTLILRRRKVS
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MUTL_BRUSU
Sequence: MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CYAY_VIBC3
Sequence: MNETEFHQLVDSQLERIEAAIDEAGADIDYETSGNVMTLEFDDGSQIIINRQEPMREIWLASKSGGYHFKSIDGEWICSKTGLELLTLLKQECDKHADEPIDWV
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: PURE_ECO57
Sequence: MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.
Protein: MIAB_SHISS
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGSTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.