PharMolix/UniProtQA huggingface dataset:
Protein: Y208_BORBU
Sequence: MKTIKKDSEFYDSLATLKKHINKYIEEKVLKYSISSQLYKLEKPEIIELIKISNDYEKEKNAFNTSLEECYYKNTQNEAIKKWILEIVRNKNFIQISKEANLNTKKLGTTYKLKSSNFLKLIEIQNSPYYSQEKKDIYKQIILNFSSNINIDSLEQTIDILVAVRNRNKIKILNILNKNLKYRPENQKVFKSSLTNKESRLIKLKRMLILTYWPVGCLSKNIFIKILIKXYKYLEEEILALKYNEILNYLRALKTLSLNEIFYKGSSKNISFNYFFSDFTQYAPKDFQDTLKCYLYVIEKTITKKYLTWFFKDKISNNWESFIDALEYIEKHKLINIKEKIKEIITAKFQTEDFFISFDKTNFNPYESSIFKERYIKSAFLEIIMHYVKKNSQNIETYGWIAFYIYADNKDKKIFCQRMKEFFKSKTFEIQNQIFVYFLSFYPNIEYKHFKFISDILLYLDENKITIPKKIIKIQKINPNQLDYQKSYLLIKSLKTRSRILKIIIKNIRFNLIEKLEDENEKKLLPAMCYLIYCENLVELKNNRKIKSNEKNSLLEFISFFKTKLKQKINFKKELMKSKGI
What are the official names of this protein?
Uncharacterized protein BB_0208.
Protein: RCAN1_BOVIN
Sequence: MHFRNFNYSFSSLIACVANSEIFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQENEEEDEMERMKRPKPKIIQTRRPEYTPIHLS
What is the function of this protein?
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A.  Could play a role during central nervous system development.
What are the official names of this protein?
Calcipressin-1, Down syndrome critical region protein 1, Regulator of calcineurin 1.
What is the protein family that this protein belongs to?
Belongs to the RCAN family.
Protein: SYD_VIBC3
Sequence: MRSHYCGHLNKSLVGQTVELCGWVNRRRDLGGLIFIDMRDREGIVQVVVDPDMADVFAVANQLRSEFCIKLTGEVRARPESQVNKEMATGEVELLARSLEIINRSDVLPLDFNQKNSEEQRLKYRYLDLRRPEMSDRIKLRAKASSFVRRFLDTHGFLDIETPVLTKATPEGARDYLVPSRVHKGSFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMTAEQVRAVTEKMIREMWLELLNVDLGDFPIMPYSEAMRRFGSDKPDLRNPMELVDVADLLKDVDFKVFSGPANDPKGRVAALCIPGGAALTRKQIDEYTAFVAIYGAKGLAWLKVNDLAAGMEGIQSPVAKFLTEEIIQAIIERTQAQTGDIILFGADSAKVVAEALGALRLKAGKELGITNESAWAPLWVVDFPMFESDDEGNVAAMHHPFTSPLNLSPEQLKANPEEALSNAYDMVLNGYEVGGGSVRIHNAEMQSAVFDILGITPEEQRLKFGFLLDALKFGTPPHAGLAFGLDRLVMLLCGTENIRDVIAFPKTTAAACLMTDAPSLANPAALEELAIAVKLATKDKA
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNC_BOVIN
Sequence: MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYKMNHVLECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).
What are the official names of this protein?
Cyclin-C.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: C19L1_HUMAN
Sequence: MAQKPLRLLACGDVEGKFDILFNRVQAIQKKSGNFDLLLCVGNFFGSTQDAEWEEYKTGIKKAPIQTYVLGANNQETVKYFQDADGCELAENITYLGRKGIFTGSSGLQIVYLSGTESLNEPVPGYSFSPKDVSSLRMMLCTTSQFKGVDILLTSPWPKCVGNFGNSSGEVDTKKCGSALVSSLATGLKPRYHFAALEKTYYERLPYRNHIILQENAQHATRFIALANVGNPEKKKYLYAFSIVPMKLMDAAELVKQPPDVTENPYRKSGQEASIGKQILAPVEESACQFFFDLNEKQGRKRSSTGRDSKSSPHPKQPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLRRFFKSRGKWCVVFERNYKSHHLQLQVIPVPISCSTTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNVPDKSDWRQCQISKEDEETLARRFRKDFEPYDFTLDD
What are the official names of this protein?
CWF19-like protein 1, C19L1.
What is the protein family that this protein belongs to?
Belongs to the CWF19 family.
Protein: PDX12_ORYSJ
Sequence: MASDGTDVVALYGGANGLSHKSGSFSVKVGLAQMLRGGVIMDVVTPEQARIAEEAGACAVMALERVPADIRAQGGVARMSDPGLIRDIKRSVTIPVMAKARIGHLVEAQILEAIGVDYVDESEVLTLADDAHHINKNNFRVPFVCGCRDLGEALRRIREGAAMIRTKGEAGTGNVVEAVRHVRSVMGDIRALRSMDDDEVFSYAKRIAAPYDLVMQTKQLGRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPALRARAIVQAVTHYSDPKILAEVSSGLGEAMVGINLSDPKIHVERFAARSD
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by PDX2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.  Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit PDX1.2, PLP synthase subunit PDX1.2.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: AUSX_EMENI
Sequence: MFIISQYREHRSLSILTQTCTIFRSMQVSSKHENLSVSFHLTPLQVLIITGTSSGIGLAAATMALEEGAKVLGVDISKPPDSLARHANYQFFQADLSHPEAPARVVEACSRTYGDRIDGLLNIAGVMDLNQSADSLSDNVWERCISINLTAPVKLMREVIPIMKLRGKGSIVNVASKAALSGAVSGVAYTASEHPWP
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster A that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Short chain dehydrogenase ausX, Austinoid biosynthesis cluster protein X.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HSP1_RHIFE
Sequence: MARYSCCRSHSRSRSRRRRQRCRRRRRRSCGRRRRACYRRYTVRYRRRRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HCYB_PANIN
Sequence: DALGTGNANKQQDINHLLDKIYEPTKYPDLKDIAENFNPLGDTSIYNDHGAAAEALMKELNDHRLLEQRHWFSLFNTRQREEALMLFAVLNQCKEWYCFRSNAAYFRERMNEGEFVYALYVSVIHSKLGDGIVLPPLYEITPHMFTNSEVIDKAYSAKMTQKPGTFNVSFTGTKKNREQRVAYFGEDIGMNIHHVTWHMDFPTWWQDSYGYHLDRKGELFFWVHHQLTARFDFERLSNWLDPVDELHWDRIIREGFAPLTSYKYGGEFPVRPDNIHFEDVDGVAHVHDLEITESRIHDAIDHGYITDSDGHTIDIRQPKGIELLGDIIESSMYSSNVQYYGSLHNTAHAMLGRQGDPHGKFNLPPGVMEHFETATRDPSFFRLHKYMDNIFKKHTDSFPPYTHDDLEFAGMVVDGIAIDGELITFFDEFQYSILNAVDSGENIEDVDINARVHRLNHNEFTYKITMSNNNDGERLATFRIFLCPIEDNNGITLTLDEARWFCIELDKFFQKVPSGPETIERSSKDSSVTVPDMPSFQSLKEQADNAVNGGHDLDLSAYERSCGIPDRMLLPKSKPEGMKFNLYVAVTDGDKDTEGHNGGHDYGGTHAQCGVHGEAFPDNRPLGYPLERRIPDERVIDGVSNIKHVVVKIVHHLEHHD
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin B chain.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SUCC_BURP0
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: BTUB_VIBC1
Sequence: MRKTFLAITCASLLSPTFYSQAQEVSADETVVVTANRFKQIDGAVLAQTVTVTKEDIKRLQANSLFDVFRTLPSVEVAQYGGRGQSASIYVRGGSSSQVLVLVDGVRMPRAIMGGIDFNQFPINSVERIDYIRGARASIYGSEAISGVINIITRAPINDDSGRVSAGYGSNNHKKGTFVVSKPVGEGKHFKGVLGYEKTDGFNVKPQPGLNDGDEHGFETLNLKLGYQQNFSDNLSGYVGVSAYNNEYDYDNSSIWSGHEKKTGEVEYVGTDLSLEYNKDVYSSELKLAYGQQDNYDHKSGQNKSTGDHVAIEQFNAIWLNSYSVNEELSIGGGLDYRTEKLAKGYIAPSDRGPAKDYDPEKNPRTNFGVSAIAQYAYDVWTLEASVRNDDNNQFGNNTTWQTAAGWSFYEGYELTLSHGTAFRAPSFVDLYYPGYEMPNLKPEESENTELSLSGAVSIVDWTVTGYYNEIENMLIWEGAGMQNVGEAEIKGVELEVKLDTDIVSHEFYLDYKDPVDKSGAEDTQLAYRSKRGAKWNAYATFDQWTLGSQYLYQGERFNGSTRLPSYSLWNFTASYAVNQNWDINAKLSNAFDKDYEMYVGYVTPGRQYFVSADYRF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: HGD_HUMAN
Sequence: MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN
What is the function of this protein?
Catalyzes the conversion of homogentisate to maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: IDI_ECOSM
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSPWMVMQAANSEARKLLSAFAQHN
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_LEPIN
Sequence: MKSIVIVAGGTGGHISPGVALAEVLTELKEKIGYENLYLYSLVRNKNNPDLEQAPCPVLWHNLPPLSSNFFLFPIRYTIQIIKTFFIFKKLNIDVVIGMGGYSTVSSILYGIFFRKKIYLCEQNTIPGNVNRLFFRFASKVAFSLPPKNSKIPCDYQVLGNPLRKKTIPKMSLKFFEKYDTKKKKQFNVLVMGGSQGARQINNIVIALMSHEEINKQFRFRVLTGSALYEEVSKKSKKDAELISYSDNMKEHYEWANFVIARSGSGVLSECAAFALPMILIPYPYAKDDHQMANAKYFELNGAAIVVDQKDEDESHLFRVLDQMANDVNLLNDMSISSLECSHVDASKDTAKYFFSLD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PGCA_RABIT
Sequence: STAPLTPRIKWSRISKDKEVVLLVANEGRVRINSAYQDKVSLPNYPAIPSDATLEIQSLRSNDSGIYRCEVMHGLEDSEATLEVVVKGVVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAASECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEXFMDIPENFFGVGGEEDITVQTVTWPDVELPVPRNITEGEARGSVVLTAKPVLDVSPTAPQPEETFAPGLGATAFPGVENGTEEATRPRGFADEAALGPSSATAFT
What is the function of this protein?
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues.  A major function of this protein is to resist compression in cartilage.  It binds avidly to hyaluronic acid via an N-terminal globular region.  May play a regulatory role in the matrix assembly of the cartilage.
What are the official names of this protein?
Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
Protein: CAH_RHIL3
Sequence: MPSLRAHVFRVPADGPDDVAGVEALFASGLQANNIVAVLGKTEGNGCVNDFTRGYATRSFETLFSRYGVDGVSIIMSGGTEGALSPHWTVFARETVETPGERALAIGVSRTPALSPEHLGRREQILLVAEGVKSAMRDAGIDDPADAHFVQIKCPLLTSRRIAEAEAAGRTVATHDTLKSMGLSRGASALGVAVALGEIDATSINDADICTRFDLFSRCASTSSGVELTDHEIIVLGMSAKWSGPLSIDHAVMRDAIDAHSVRKARERLPENSRLAAVLAKAEPDPSGEIDGRRHTMLDDSDIAGTRHARAFVGGVLAGIFGITDLYVSGGAEHQGPPGGGPVAIIVEKEQ
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: MIAA1_SYNAS
Sequence: MMKNLVVILGPTASGKTRLAVRLARDLKSEIVSADSRQVYRGMDIGTGKDLDEYRIDGEEIPCHLIDIVDPDYDFNVFEYQSRFYRCFEEILSRGIVPILVGGTGLYLSAVLENYRMVQVPENLDLRESLKAEPLERLQQILLEITPRIHNTTDLLDRGRLLRAIEIAQHSGRRGLRESPEHPRIEPLVFGVRWNRDLLRKRIALRLKERLSAGLIDEVKELHQSGISWDRLEFFGLEYRYVGLYLQSRMSYREMAEKLTIHICRFAKRQETWFRRMERHGIEIIWIEGDDYEALKEQLKGNLRS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS19_CHLTA
Sequence: MSRSLRKGPFVDHHLLKKVRDMNALEKKTPIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSETMVGHKLGEFSPTRMFKSHPVKKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NDK_LEGPC
Sequence: MAKELTLSIIKPDAVAKSVIGEIYTRFEKAGLDIVAAKMTQLSREQAENFYDIHRARPFFKDLVDFMISGPVMIQVLKGENAVAKNREIMGATNPKEAAPGTIRADFADSIDANAVHGSDSLENAAREIAFFFEPHELCNR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUN3B_RAT
Sequence: MASRSLGGLSGSRGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEEGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSEGSTPENVGPPLILDENSWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPGHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTEITSPGLTPS
What are the official names of this protein?
RUN domain-containing protein 3B.
What is the protein family that this protein belongs to?
Belongs to the RUNDC3 family.
Protein: SBNF_STAA8
Sequence: MIVVQTLFIHIYQIQFVITRRYRIVNQTILNRVKTRVMHQLVSSLIYENIVVYKASYQDGVGHFTIEGHDSEYRFTAEKTHSFDRIRITSPIERVVGDEADTTTDYTQLLREVVFTFPKNDEKLEQFIVELLQTELKDTQSMQYRESNPPATPETFNDYEFYAMEGHQYHPSYKSRLGFTLSDNLKFGPDFVPNVKLQWLAIDKDKVETTVSRNVVVNEMLRQQVGDKTYEHFVQQIEASGKHVNDVEMIPVHPWQFEHVIQVDLAEERLNGTVLWLGESDELYHPQQSIRTMSPIDTTKYYLKVPISITNTSTKRVLAPHTIENAAQITDWLKQIQQQDMYLKDELKTVFLGEVLGQSYLNTQLSPYKQTQVYGALGVIWRENIYHMLIDEEDAIPFNALYASDKDGVPFIENWIKQYGSEAWTKQFLAVAIRPMIHMLYYHGIAFESHAQNMMLIHENGWPTRIALKDFHDGVRFKREHLSEAASHLTLKPMPEAHKKVNSNSFIETDDERLVRDFLHDAFFFINIAEIILFIEKQYGIDEELQWQWVKGIIEAYQEAFPELNNYQHFDLFEPTIQVEKLTTRRLLSDSELRIHHVTNPLGVGGINDATTISET
What is the function of this protein?
Catalyzes the condensation of L-2,3-diaminopropionic acid (L-Dap) and citryl-diaminoethane to form L-2,3-diaminopropionyl-citryl-diaminoethane, the third step in staphyloferrin B biosynthesis.
What are the official names of this protein?
2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase, Staphyloferrin B biosynthesis protein SbnF.
What is the protein family that this protein belongs to?
Belongs to the IucA/IucC family.
Protein: DEF40_ARATH
Sequence: MAGIANGVGLLISFMLICGGMPKGHALGTSPYCEKVLSRFAPPGNCLKKNGNALCKESCANEQFREGVCLHLPKPQSKLNCYCSVLKCP
What are the official names of this protein?
Putative defensin-like protein 40.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGRM2_HUMAN
Sequence: MGTRDDVPEAKVLVPVAVYCGSIPRTSAGPRVLPPGSINSSLPHGEGSLQPEPRALLNNEEPSQLLRGLGQLGGLKLDTPSKGWQARNGHPRNLRALSLGDQPLVLLPSPESEANSVARDTIQIKDKLKKRRLSEGLAASSRASLDPGGGPQGVPLHSTIPRATSQRLLRVPRPMPLIQSIPTTPEASGVKEKGLDLPGSIPGPHELRPGAQEAQISWQYLHCNDEKMQKSLGAIVIPPIPKARTVAATPSRVPGSLPSPLPPGQGVLTGLRAPRTRLARGSGPREKTPASLEPKPLASPIRDRPAAAKKPALPFSQSAPTLTAFSFDCAREACPPLKEEDQKEIGTKIQVTISKSAREKMQLKQMKEMELLRRLEEPRTGQELTSQCLGSQRAFMKEGLLPLRGSGTLSVPTRLSGPCRNDVSIILRKWASRASLPSIPISRQEPRFARHASANSLPAVLTLGSPEWEEEEEMDLRACKELRPFSNPELGLRDALQCLNSSDWQMKEKGLVSIQRLAACHSEVLTGKLHDVCLVVTGEVTNLRSKVSHLAISTLGDLFQALKKNMDQEAEEIARCLLQKMADTNEFIQRAAGQSLRAMVENVTLARSLVVLTSAGVYHRNPLIRKYAAEHLSAVLEQIGAEKLLSGTRDSTDMLVHNLVRLAQDSNQDTRFYGRKMVNILMANTKFDAFLKQSLPSYDLQKVMAAIKQQGIEDNDELPSAKGRKVLRSLVVCENGLPIKEGLSCNGPRLVGLRSTLQGRGEMVEQLRELTRLLEAKDFRSRMEGVGQLLELCKAKTELVTAHLVQVFDAFTPRLQDSNKKVNQWALESFAKMIPLLRESLHPMLLSIIITVADNLNSKNSGIYAAAVAVLDAMVESLDNLCLLPALAGRVRFLSGRAVLDVTDRLAVLVASVYPRKPQAVERHVLPILWHFLNTATRNGTLPGPSGNIRGVVCRLSRSLQEHMGSRLLDFAASQPKHVLKTLQELLDSESLGGSRKATDRGVAPDSKTTGSSYPFQLD
What are the official names of this protein?
TOG array regulator of axonemal microtubules protein 2, Crescerin-2.
What is the protein family that this protein belongs to?
Belongs to the Crescerin family.
Protein: AIMP2_RAT
Sequence: MPMYQVKPYHGGSAPLRVELPTCMYRLPNVHSKTTSPATDAGHVQEPSEPSLRALESRQDDILKRLYELKAAVDGLSKMIHTPDADLDVTNILQADEPTTLTTNALDLNSVLGKDYGALKDIVINANPASPPLSLLVLHRLLCERYRVLSTVHTHSSVKNVPENLLKCFGEQARKQSRHEYQLGFTLIWKNVPKTQMKFSVQTMCPIEGEGNIARFLFSLFGQKHNAVHLTLIDSWVDIAMFQLREGSSKEKAAVFRSMNSALGKSPWLVGNELTVADVVLWSVLQQTGGSSGAAPTNVQRWLKSCENLAPFSTALQLLK
What is the function of this protein?
Required for assembly and stability of the aminoacyl-tRNA synthase complex.  Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation.  Blocks MDM2-mediated ubiquitination and degradation of p53/TP53.  Functions as a proapoptotic factor.
What are the official names of this protein?
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Multisynthase complex auxiliary component p38, Protein JTV-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus.
Protein: CATIN_SCHPO
Sequence: MAFRDSTRDFNRSRPEKRHASRSSSPRSFRPSNQNARANYNLPRVRDAMKEEERSRETKEMQEREFLRLQQLRRAIIRLKNDRSKPIDKLLVSVYLMPGPEWEENGEKNSIDFGTVDMFDPLSVIQSYKAEDLEEISRNIGDIQQLETNQCRLTYWKYVKMLVNSRMEHNKVGQFSRGLKVVAGEVQRILAPKSFEQLEQLEAQIQKKLKSNVPLDTDYWVDLLNSLKSYKAIAYLKKTFNEELQIRKNKLDNEEWDKAFSDAKKLSNMKDREEKLYIVPIDPKPILRAQAIPRRIQPEEQADYEKELNDHVNIVKSSTYIPISIPTQKQKPTLPKNSNLINEDEFSIANRARLEREYLQSDDAEEQEMLGDYVEGQTRVVNENGVTLKKPHYFNRVLLGFEWNSYNQAHFNEAHPPPKAVQGYRFNVFYPDLIGTGRAPTYRIERTRRKNKSDTTDLQDDVCIIRFIAGEPYQDIAFSIVDKDWDYSAKRDHGFKSSFDNGVLSLHFRFKKLHHRR
What is the function of this protein?
Plays a role in pre-mRNA splicing by facilitating excision of introns featuring long spacing between the branchpoint and 3'-splice site (ss) (PubMed:36095128, PubMed:28947618).  Recruited to the spliceosome by sde2, which may enable folding of the RNA between the BP and 3'-ss to guide the splice site towards the spliceosome's catalytic center (PubMed:36095128, PubMed:28947618).  Assists the splicing of several components involved in chromatin organization (PubMed:36095128, PubMed:28947618).
What are the official names of this protein?
Splicing factor cactin.
What is the protein family that this protein belongs to?
Belongs to the CACTIN family.