PharMolix/UniProtQA huggingface dataset:
Protein: FIXX_SALTY
Sequence: MTSPVNVDVKLGVNKFNVDEDSPHIILKTDPDKQALEVLIKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLDTALEKWEYPRGTFGVEFRYG
What is the function of this protein?
Could be part of an electron transfer system required for anaerobic carnitine reduction.  Could be a 3Fe-4S cluster-containing protein (By similarity).
What are the official names of this protein?
Ferredoxin-like protein FixX.
What is the protein family that this protein belongs to?
Belongs to the bacterial-type ferredoxin family. FixX subfamily.
Protein: RL7_LISMC
Sequence: MALNIEEIIASVKEASVLELNDLVKAIEEEFGVTAAAPVAVAAAGGAAAEQTEFTVELASAGDSKIKVIKVVREITGLGLKEAKELVDNAPKALKEGVAKEEAEEIKAKLEEVGANVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VCLA_PEA
Sequence: DNAEIEKILLEEHEKETHHRRGLRDKRQQSQEKNVIVKVSKKQIEELSKNAKSSSKKSVSSRSEPFNLKSSDPIYSNQYGKFFEITPKKNPQLQDLDIFVNYVEIKEGSLWLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQGLREEDDEEEEQREEETKNQVQSYKAKLTPGDVFVIPAGHPVAVRASSNLNLLGFGINAENNQRNFLAGEEDNVISQIQKQVKDLTFPGSAQEVDRLLENQKQSYFANAQPQQRETRSQEIKEHLYSILGAF
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Provicilin, Type A.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Protein: PER_ANTPE
Sequence: MNNMDGSENNAKVSDSAYSNSCSNSQSRRSHSSKSTHSGSNSSGSSGYGGQPSTSSSSNDLSDQKKEKELKKKKQVETLMPDTQIEVECRPEEDVINIPSEEGGAADDVLVPSPKQTLQTDNDIADIEVAIPDTNNDKEEAIVYNTSLINPGTACPFGRPALSNCNGFSCVISMHDGVVLYATASLTSTLGFPKDMWVGRSFIDFVHPRDRNTFASQITNELAIPKIVSLTEETDQTMENPGSTMVCRIRRYRGLSCGFSVKNTTTAYLPFLLKFKFKNVNEDKGNVIYLVIQAVPFFSAFKTSNEVLAKTVSFVIRHSADGNLEYIDAESVPYLGYLPQDITNRDALLLYHPGDLGYLQEIYGSLVKEGNVTRSKTYRMMTQNGHYMKVETEWSAFINPWSKKLEFVTGKHYIIEGPANPDVFQNPENVLKLTEEQKNQAKMYRDSIIRIMKDVLTKPAEIAKQQMSKRCQDLAHFMEMLIEEQPKPVDDLRLEIQDADHSYYERDSVILGGISPHHEYDSKSSTETPLSYNQLNYNDNLQRYFNSHQSNAFVDNNLLPSRNPLYLSAPHFSESIKNVPSAMEYSGDVIDLTGPGETSGVIVFNKSPTMGLKTGKPIRLTESSLTKHNAEMEKELMKIHREHRCYSKGDRVKVSNEARQKKKEHLARCNAGFQTISAANNTPSVYEKPHNLKRSSKQMESEPIANKHHCPSSRQFRRKQTTCSGGFAQPPSATNPVSTSSQWSSSPVNNVNPFILGVRMQPPMPILSPLPVVSGMFPMYYTPVTATVTTSEGRPSEPNYHRNNMNNNQFQQPLGNSRLPTTICVIQCGTSRIIHSFRGTRTTGGTRYT
What is the function of this protein?
Involved in the generation of biological rhythms.  The biological cycle depends on the rhythmic formation and nuclear localization of the tim-per complex.  Light induces the degradation of tim, which promotes elimination of per.  Nuclear activity of the heterodimer coordinatively regulates per and tim transcription negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).  Expression exhibits prominent circadian variation in adult heads and in particular in the photoreceptor nuclei.
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear at specific periods of the day. Interaction with TIM is required for nuclear localization (By similarity).
Protein: YVBE_VACCW
Sequence: MYNSSIHTPEYDVIIHVIEHLKHHKQCVQTVTSGMVFTSPVSSSICTKSDDGRNLSDGFLLIRYITTDDFCTIFDIIPRHIFYQLANVDEH
What are the official names of this protein?
Uncharacterized 10.5 kDa protein.
Protein: ZC3HF_CAEBR
Sequence: MPPKQAPSKKAENKRKEKVIEDKTFGLKNKKGNKNQKFVAQIENQVRNNNTRMDLVRQQEAAKKKEKDELLDIQNLLKPVEQKVAKDVDPKSLLCVFFKQGLCGKGAKCKFSHDLAVAQKTAKKNLYADSREVEKDETNENWDKEKLDEVVNKKNKGGHVIDIVCKYFLEAVENNKYGWFWECPNGGDKCQYRHCLPEGYVLKKDRKAMEAQKEDEISIEELVEKERAALNSKDLTKLTLQTFVAWKKKKLKERKEKEEADLKAKKEKIKSGKHNGMSGRDLFLFDANLINNDDDEAGDIEMEKEEVDENEKVFEIDANFFKFDGMDDELTNQMSNSTAAVSSVAGAVAKMDINEDLFDIDEDVGDLDSDSDED
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 15 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZC3H15/TMA46 family.
Protein: DAPB_SYNSC
Sequence: MTAPIPVVVAGALGRMGAEVIKAVVGAEDCSLVGAIDNTPGKEGADVGLELGLGELEVAVTADFEGCLCAVSQSVRDSGSGAVLVDFTHPSVVYEHTRAAIAYGVHPVIGTTGLSPEQLNDLTEFSAKASVGGAVIPNFSVGMVLLQQAAAAAARFYDHAELTELHHNRKADAPSGTCIKTAELMEELGKSFNPEEVDEHESLAGCRGGQRDSGLRLHSVRLPGLVAHQEVMFGAPGETYTLRHDTIDRSAYMPGVLLTVRKVGNLGSLVYGLERLI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_RHOPA
Sequence: MTASLKAIDGSAELTTLMTDLGRQARAAARTLALAPPEQKNRALEAMERAIRAGADKILAANAEDVADAKAAGTTSAFLDRLTLTPARVEAMAEGIAVVRGIADPVGTVTESWQRPNGMTIERVRVPLGVVAVIFESRPNVAADAGVLCLKSGNAVILRGGSESFRSCRAIHDRLVQGLREAGLPDAAITLVPTRDRAAVGLLLAGLDGSVDVIVPRGGKSLVARVESEARVPVFAHLEGVNHVYVDRSADLEMAKSIVLNAKMRRTGVCGAAETLLIDRAAATTHLAPLVTMLIDSGCEVRGDQTVQQVDPRVKPASDEDWDTEYLDAVIAAKLVDGVDGAIVHIHNHGSHHTDAIVAEDAQAAAKFLGEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGAEQLTTFKYRIHGSGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPC_ASPFN
Sequence: MSATVDNTEANASPPKEFTLRSTIALIGAFMALFCTLGFQNAFGVFQAFYHATILRDHSEFDIAWIGSLLTFMIFFFAAPAGVLVDRVGPTHSLTRHLQPLLTFGAIATILATFMISLCKELYQFLLAQGILLGIGNAFLLCPAMATVTRLFDHHRGAANGIMIAGSSIGGIIWPIMLDQLLNKDGVSFGWTFRIVGFVVLPLCLFMVATIRPAPKTPHDSDREGIELSHGESESDHKAQGAEGPAAIIKNPTFLILCAGLSVATFGLFSPLFFISTYATDQGLSVSLAFYLVSMLNGASMVGRVSTGFLADRYGNFNLCFLTIASSGLIAMCWTKATNTVGIIFFALAYGYTSGVSPSDLKKNPPGPNTAVAGHVQSPNPVCRPALDARVEGGCRRHSLCRASNSVSIVLFSRIARSCRLTHSYSGLVGTPISGRLLKHGYLALSMYSGAALLAGAGLVLIARLRQNTKLMAKV
What is the function of this protein?
Efflux pump that may be involved in the secretion of leporins (PubMed:20447271, PubMed:26051490).
What are the official names of this protein?
Leporins efflux protein lepC, Leporins biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_METCA
Sequence: MDKKQARLKRAAKTRHVIRAMGANRLTVHRTPRHIYAQVISPDGGTVLAAASTLESAIRETLPVTGNKDAAIAVGRRIAEKALAVGISSVAFDRSGFKYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ESXT_MYCTU
Sequence: MNADPVLSYNFDAIEYSVRQEIHTTAARFNAALQELRSQIAPLQQLWTREAAAAYHAEQLKWHQAASALNEILIDLGNAVRHGADDVAHADRRAAGAWAR
What is the function of this protein?
Induces apoptosis of host cells via activation of NF-kappa-B.
What are the official names of this protein?
ESAT-6-like protein EsxT.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-4 / type VII secretion system (T7SS).
Protein: RL20_STRS2
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHLLFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAAAFTALADAAKAKLAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DNPH1_MOUSE
Sequence: MAASGELVPCSVYFCGSIRGGREDQALYSRIVSRLRRYGKVLTEHVADAELEPRGEEAAGGDQFIHERDLAWLRQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEEEVETMLHRYFEAYLPQGTASSSNPSACLNPTVLEKI
What is the function of this protein?
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.  Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
What are the official names of this protein?
2'-deoxynucleoside 5'-phosphate N-hydrolase 1, c-Myc-responsive protein Rcl.
What is the protein family that this protein belongs to?
Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPP_XANC5
Sequence: MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L_TUPVT
Sequence: MESWPEDNVDSFESSPFWELEEDWVAPKNKGQLGSVKNTDYNLNNPLLSDGLTAFCRYLKGKSFDKIFHLHRWISTKALMEESKIRVEGNPEALHHWMGEYFLNQDIPLSRFKPLWDLVIKHSRLTHIVPELFVRSLGRYHLPYLERGERNWEKLYLTKFMEWHLLVIVMNHFEDDLSSIAPLINLKKKSSAHGICYSARVSGVGEVLVFDWILVLPNGLILNKNFVLMIKDTLLARFQTLITMYPRHDGKFTLEDVRTLLKVYSLGDRMLYTIGNEAYDLLKFVEPICNLRMTQLANKHRPLIPEFPNFRQYLEAELPELCKLSPIIMELWDTITSLDDPELVVQIFGCFRHWGHPFIDYGEGLQKLYEQVTMPKIIDDELAQALGSDLAYLVLRSQFKKTKKWFVDPSKLPMNHPLKKFVETSTWPTPKVIEDFGDKWHTLPLTQCFDIPDLVDPALIYSDKSHSVNRRSLIQHVSSGAYSKFPTKRVLTTFLTEPARDWKSFLQQINDRGLPDDALCIGLRPKERELKRAGRFFALMSWELREYFVFTEYLIKEHFIPLFKGLTMADDMTGVIKKLLECSNGHGETDYSNITISNHLDYSKWNNHQRYESNKYVFQVMGSFLGYPNLISRTHEFFQKSLIYFINRPDLMVVKGNTLEPKGQMRVCWNGQAGGLEGLRQKGWSIVNLLLIMRVGKLRNTEIKILAQGDNQVMNSHYKLPAYRTDFELLECISEIIRNNKYIMQEVDHWTQRLGLIINKDETMQSADFLIYGKVPIFRGNITIPESKKWSRVNCVTNDQLPTFGNVMSTVSSTALSVSHFSNSFLDPIEFYNLLGNFSRILLEMFNPVLNKSLLQFFTDWSQFEDVGYLISVLYLDPSLGGVCGMSLSRFLIRAFPDPVTEGLSFWRRLSTVTSDPNLRKLFLSFGNPPLGRFKMEDLTKLMEKPESLNIPSSLSAQILIRTEIREILRRNVRVIKNEIIVNAISYGMQAEEHLIRFLYSIKPLFPRFLAEFKSSTYLGLTESLVGLYENSKTIRNRFLGQREREIDDLVQRSEYVGIKYLVQVRKERTTPGPWNCSASHADRLRRLSWGQPVIGATIPHPFEMLGKVCYLFRGSGCECPDSSNYTTTFVNWDAESVMSRKGPFLPYLGSKTSESTSLINPWERETIIPLIKRAAKLRNAINWFVRSDSLLARSILNNLRALTGEDPGQGNPGFFRTGSALHRFACSRQSSGGFSALSPAYLSRFLTTTDTLQGIGDRNYDFMFQSLILYSQSSLCVQINRNVQGIVHHHISCNECLREITEPFLEGSFEYKPKDVSRHVRKWIPGGNQILTEKLRLEFQYGNWEAISDAEKTYHVGRAIGFVFSDYAFSSSAQLEESSLFPLSIRNSLTPELFYEGLIDGLIRGCSIQITHRRNVALLKKPRETLVGSVFFAITKITLNTPFLSLVRVGAIHDYIIRNSHRTPPSYPLSKWDLGGILRHYLKTRFLHLLRTGYSSRYTSVWIFADLAGIEVGGLLCLSSHLLEYSVSPNKTKLGAERLRKFKEIEINMRQKTQVDLSCLDLRRVYLCKSEVRHSVKSIDKKTVQSEAPLYKFEEEEVGYVVAWDVSYLSAPALSPKEELTVPRLQCPLISGLRTIQLATGAHYKVRSILNHFNIQFDDFLCGGDGSGGLTAMCLRWNRFSRGIFNSLLDLSGYDLRGSRPSEPSAIAALGADAARCVNRQTCWQHPSDLTDKSTWNYFVDLKAEFGLTIKLMIFDMENRDEQSFLIEDQIIDYLPRLLSRSGSLIFKTYCHRLISQQNPLLLKRLGRHFKRSCLVQTEFTSNFSSEVYVVLMDYVPGNSLAGIVDYTEMTRFLGKRFVFSNPVDEFKRALGIKRKAMEKGIPSELLPDPEVELATVLEICGLESGRAASVAEICCSKSISPKVKYLFVRSITFCSFFNLTSGFSERPHVPSDSKLLRFFSFFIGLEYWWSWVSEELPRFERMNQFLREDLFITHESKKGKDFWVRKVFLGAFDIGVVKRLRLQGSLAGIGSAIRSLRRAVPLNETGLTLSVSELIGRFDRGLTPSVLSSRSNLLTYIQDYRSNLDLPVSSEIINTGIRGDMATTE
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: VATE_PYRNV
Sequence: MSLFEDLINSKIRELEDLKRNLLVNIETNIRREADAALSKFSAQLANVESEATLERERIIYNAVVEARRKIAEVYDQMLKDLVNAVYEEVDKMRGAERYVKFLTSLLETAEKYVQTKDVVIYASPKDKGVVEAVARNLGLTGIVAEKDIRGGVVVTTRDGSITVDYSLESLIANKIEELKHLLYQMTYER
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: FMFX_BORPE
Sequence: MQAKTFLLGAALAGVALAAHAEDGTIVITGTITDQTCTIEDPSPGYIKVVHLPTISKSALKNAGDVAGRTRFDIKLKDCPTTVNTLKLYFEPGPTTDYGTKDLKAYKQAWYVDAATLLKSPPSVTEAKGVQIRLMNLNGKQIPMGETEPNQHAAAFSGTMQAGQAKKSFTLHYLAGYVKKASGEVEATMLTTYVGFSVVYP
What is the function of this protein?
Bordetella pertussis is the causative agent of whooping cough.  An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms.  It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B. pertussis are prime candidates for being involved in this process.
What are the official names of this protein?
Fimbrial protein FimX, Pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium. Note=Pili structure on the cell surface.
Protein: RS3_CHLAA
Sequence: MGRKVHPIGFRLGYIKDWQSKWFAEGEEYTRQLHEDIELRKLISKELQSAGVSRIEIERSANKIEISVYTAKPGIVIGKRGTNVDTLKSALERKTGKKIKLNIKEIHQPELDAQLVAESIGEQITRRVSYKRAMKQAVQRAMRLGAQGVKVRCSGRLGGAEMSRVHEEAEGRVPRHTLRADIDYAQVHAHTTYGRIGVKVWIYKGEVFPNQVAKSPAEPATTAPTPAPERRERQPRRNSNASA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL32_NANEQ
Sequence: MIFKLIIKPKGMGHYLKIRRKLKRKKPEFLRTNWYRKKAFRNDPKWRWGHGRDNKFRLKMKGKPRPPEPGYRSPRKVRGLLPNGLKPVIIHNVEELTKIKEGEIAVIHHAVGKRKRQQILEKAKELSIPIANPVL
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: EIF3A_VANPO
Sequence: MAPPVLRPDNAIKRADELISVGESQAALQSLYEYLTARKIRFAQPSTVEPIVFKFLELGVDLKRGRLIKDALHQYKKLVQGSQDGLSSVGAVARKFIDCVETKMAFEHLKAEESQTEEDDDLEGGVTPENLLKSVYIQDQSVAGFNDEVVTSWLKFTWESYRAVLDLVRNNSQLEITYAGVVNRTMQFCLKYNRKNEFKRLAEMLRQHLDAANYQQSKIGSNIVDLSDSETLQRYLDQRFLQLNVSVKLELWHEAFRSIEDVYHLMKMSKHTPKSSTLANYYENLAKVFLISNAQLLHTATWEKFYRLYQSNPNATEEDFKKYSSIILLSALSTPLDILPTVGYDPQMRLYRLLGLESRPTRNEMIELAKQEDIYKHIDEDIIKLYEIMEINYNADTIKTEIAALLPKLEAKPYFKQYINQLRNVLLRKNYVSLSETENAIPTDALYDKASLPGVLSLPHWDMEKTLLQAAVEDYVSISIDHDSNTVTFFKDPFEIISKAAGTVEEEEEEEEEEGEEVEGEEAETGEEIVEEGEEHENEENKEPEPVITRTTFIRNRLAELSNVLEEIDAFKNASYLEKVKLARETLITQTKDSIENLKQIAEDRAKRAQEQKKKYMASAAVRAEEDAEIRQRQILEEKAALEAKLEQDAHRRLVEKKKREFEDLKQREIQKFIDEFNKKDHAAKIASEEVQGLDIKEIKTLIFSKLSQDKSELEDRMTSSLQKLDHAERAYRKSELPLLRKEAESLKETDMNKFNDMKSKIVDTARAEFDAKMEDHNRLVGVYNDYVSLKDRLTTTVEEKFKLIRAENAAKFEAAKKARIEEVRKQRYEELVAERKAEIEAEEREERAKKQEETARKQKEMEEAAERKSKASSAAAAKSILTGGNDARSAKLDEIARRQREIEQAAERKAQGPSASTEAPDDEGRNLTYAEKMKLRRASKK
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_STRM5
Sequence: MTDVSAPVFDGKAFAAQLSTAPGVYRMYAADDTLLYVGKARALRNRVGSYFNGSPKNARIMSMISQITRMDVTVTRSEAEALLLENQLIKSLSPRYNVSLRDDKTYPHVLLTREDWPRIALHRGPRAIPGRYFGPYPGVTAVRETLNLMHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVELVPAPEYAESVRRAALFLEGKSDELTRELGEQMQAASEALEFEQAARLRDLISSLRSMQTRQYVDGRAADLDVLAVAMQGSQACVLLLAFRDGRNLGTRPFFPRTNGEESPEEVLAAFVSQYYIEFEPPREILLDREIPDADLLVAALSASAERKVQLKWNVRGERAGYVELASRNAQLTLATELNSRNAQHARSDALRDMLGLAEPVKRVECFDISHTLGEATVASCVVFDAAGPVRAQYRRFNISGIEPGDDYAAMRQAIDRRFRRAVEEQGVLPDVLLIDGGAGQLAQAQAALADLGVEGVLLVGVAKGVERRAGHEALVMPDGRELRPGAANPALQFIQQVRDEAHRFAITGHRGRRQKARMTSKLEDIPGIGPRRRASLLKHFGGLVGLKAAGEAEIAKVEGINDALAARIYANLHGLATPDAAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_STAAW
Sequence: MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNHEDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQVGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILSMIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHTQGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_HELPS
Sequence: MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTTLNQVGSVMSLDATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKIKKLEKDKEISEDESKKAQEQIQKITDEAIKTIDESVKNKEDAILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC1_ANTAG
Sequence: MIYQEENQHLRIGLASPEEIRGWAERTLPNGEVVGRITEPYTLHYKTHKPEKDGLFCERIFGPIKSGICACGKYRSIENQREYSKICEQCGVEFTESRVRRYRMGYIELACPVTHVWYLKRLPSYIANLLAKPLKELESLVYCDLFLARPIAKKPTLLKLRGLFKYEDQSWKEIFPRFFSPRGFEAFQDREVATGGNAIEKGLASLNLQIVMDRAYMEWRNLTEQKSTGNEWEDRKIQRRKDLLVRRMELAKNFLQTNMKPEWMVLSLLPVLPPELRPMIELGEGELITSDLNELYRRVIYRNNTLLDFLARGRSTPGGLVVCQKRLVQEAVDALIDNGIRGQPMRDSHNRAYKSFSDLIEGKEGRFRENLLGKRVDYSGRSVIVAGPYLPLHECGLPKEMAVELFQAFVIRGLIGRYLAPNLRAAKSMIQDKEPIIWKILKEVIQGHPVLLNRAPTLHRLGIQAFEPILVEGRAIRLHPLVCAGFNADFDGDQMAVHIPLSLEAQVEARLLMFSHTNLLSPVTGNPVSVPSQDMLLGIYVSTIRSNRGIYQNQYHPYDYRNKNFSYKMFYFHSYDDILKAEKQKQINLHSPLWLRWQVDLHIVTSIDREVPIEIQYESLGTSSQIYENYQFRKNRKEKILSMYICTTAGRILFNQQIEEAIQGFFEVSQHRSRPLPAIIA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UCPB_DICDI
Sequence: MTSQESIGIKFLFGGLSCMGAAVVSNPVDVLKTRFQIHGEGIDSKSLGLVNGTIKIIKNEGISAMYKGLTPSLLREATYSTLRMGGYDVIKNYFIDSNGKTNLLSKVTSGALSGALGACITSPTDLIKVRMQASSKGVKYDSISSAFKEIIAKEGIKGLWKGVGPTTQRAALLTASQIPSYDHIKHMILDHGIIQVDGLQVHIVSSIFAGLIASITTSPVDLVKTRIMNQPFDSNGVGLIYKSSYDCFKKTFQSEGISGLYKGFLPNWFRIGPHTIVTFILYEYLRKVSGIKPI
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial substrate carrier family protein ucpB, Solute carrier family 25 member 30 homolog, Uncoupler protein B.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIBL_GALME
Sequence: MLPFVLVLLVATSALAAPSVVISQDNINNIAPRVGNGRPISSALIDRAFEIVDGGDTNIYILTIQQILNDLADQPDGLSQSLAVTQAVAALGELATGVPGNSCEAAAVIDAYANSVRTGDNSALSIAVANYINRLSSNIGLISQLASNPDSLRYSSGPAGNCAGGGRSYQFEAAWDAVLNNANPYQIGLINEEYCAARRLYNAFNSRSNNVGAAITAGAVVAQTQAAQIILPSLVNVLSAVAAGGNVAGAAAQAGQALANAAANVQL
What is the function of this protein?
It is likely that the major role of L-chain is to prevent the retention of H-chain in ER by forming the disulfide linkage.
What are the official names of this protein?
Fibroin light chain, Fib-L, L-fibroin, PG-1.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_ECO45
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQVMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.