PharMolix/UniProtQA huggingface dataset:
Protein: UGPC_CUPNH
Sequence: MAKLSLRNVQKTYAGSVQVVHGIDMEIADGEFIVIVGPSGCGKSTLLRMVAGLETITGGEIHIGDKVVNNLEPAERDIAMVFQNYALYPHMSVYDNMAYGLKIRGMAKAEIAQRVNHAAGILELAPLLDRKPRQLSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLELKELHRRLGTTSLYVTHDQVEAMTLADRMMVLNAGRVEQIGTPLEVYSRPASTFVAGFIGSPPMNLIPVARNAGGDTGAQMRVVAKEGEAANATLGHLPMGLHLPEQALLGLRPEHIEPCAAHEAIAEVDVRVVEALGADSFAYGSLGGQAVVVRLDSHAHVRAGDRLPVTSSAEHLHFFAPDTGKRIEA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PPK1_NITWN
Sequence: MDSIQAIAPEEKKPELELDSAIRASPERFINRELSWLHFNRRVLEESVNPGHPALERVRFLSISANNLDEFFMVRVAGIKAQVREGITERSPDGLTPSEQLVLINETVSDLASDQQAIWRDLRNMLAGVGIVLIDGKDVTKAERSWIADHFLHNIFPLLTPLAIDPAHPFPFIPSLGFTIALQLARTSDGKPMNALIRMPGKIDRFLRIPAASKDDPVRLITIEGATSLFINRLFPGYTVKGQGAFRIIRDSELEIEEEAEDLVRLFETALKRRRRGSVIRLEIEAAMPAELRAFVQRALSAADDEVLLVDGVLAMNELSQLTRLDRPDLEFVPYVPRHPERVRDHGGDVFAAIRQKDLIVHHPYESFDVVVQFLQQAARDPDVVAIKQTLYRTSNNSPIVRALAEAAEAGKSVTALIELKARFDEEANIRWARDLERAGVQVVYGFLELKTHAKLSLVVRREGGSLATYVHTGTGNYHPVTARIYTDLSYFTSDPIIGRDAARVFNYITGYAEPSDIERMAVSPLTLRNRILDHIRGETTFARNGKPAAVWMKMNALVDPDIIDALYEASQAGVSVELIVRGICCLRPGVPGLSENIRVKSVIGRFLEHGRIYCFGMGQTMPGPKAAVYISSADMMPRNLDRRVEVLCPLQNATVHQQVLEQIMVANLKDTEQSWRLLPDGSSTRMKAAKGEEPFNLHNYFMTNPSLSGRGKSLKESSPRRLTRRSERQPPA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: LGT_RHORT
Sequence: MLFALPFPAIDPVLVEIGPFAIRWYALAYIVGLLGGWWYTRFLSRRSRPPVMSDADVDDLLVWATLGTILGGRLGYVVFYNAAHFLANPLEIPMLWHGGMSFHGGLVGVITATVLFCRSRRLSVARVGDLVALVAPLGLFFGRLANFINGELFGRPAPDVPWAMVFPHGGPLPRHPSQLYEATLEGLVLFCLLGLLWRFTALSRKPGQIIGLFLIGYGLSRITAEFFREPDAQIGFLALGVTMGQILSLPMILAGIVVFVVARRAKPLAVPGGR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CISY_MESAU
Sequence: GAIDSKLDWSHNFTNMLGYTEPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPNDPLFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSR
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RSMH_LEUMM
Sequence: MPFEHVTVLLHEAIALLDIKPEGTYVDATLGGGGHTGEILKQLTTGTLYSFDQDDTAIQYNAEQYADEIAAGKLVIIHKNFRTLTSALADYGVTAVDGIVYDLGVSSVQFDDGQRGFSYKYDAELDMRMDQRQALTAKTIVNEWPFNELMRVLSRYGEDRFPKQIARKIEQHRENAPINTTFELVDIIKEAIPAPARRKGGHPAKRSFQAFRIAVNDELGALEDSLTQALELLATDGKISVITFQSLEDRLVKQMFREKSSAPELPAGLPVLPGQFEADYELLTRKPISPSTEEMAINHRAESAKLRGIRRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_STRCL
Sequence: MTRKNNALPKARTLIEALPWLTRHHGKTIVVKFGGNAMVNEELKGAFARPSFLVHHAGLRPVVVHGGGPQISAELDRYGLVSEFKAGLRVTTDEAMDVVRMVLAGQVQRDVWGCSIVHGPLAVGITGEDAHPISATRHRPLIDGEPVDIGRVGEVTRIDTGAVLALLEDGRIPVVSSIARAEDDGHVYNVNADTAAAALAAALGAETLMVLTDVEGLYEDWPNSDEVISRLTASELETLLPDLSSGMVPKMEGCLHAVRNGVRTARVIDGRVPHSILLEIFTDDGVGTMVVPDEPSVSEGTS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT18B_PIG
Sequence: MAASILNVLLRRLPGVSPFRGAYGVQVLLQTLCTKAPPEDDSLPQVPISPYKDEPWKYLDSEEYQNRYGSRPVWADYRRNHKGGIPPQRTRKMCIRGNKVAGNPCPICRDQKLHVDFRNVKLLEQFVCAHTGIIFHAPYTGVCMKQHKKLTQAIQKARDHGLLRYHIPQVEPRDLDFSTTHGAVSSTPPAPTLVSGDPWYPWYSWKQPPERELSRLRRLYQGRLREESGPPPELMPEVPLTAPAEASSTEPGAPQSAL
What are the official names of this protein?
28S ribosomal protein S18b, mitochondrial, MRP-S18-b, Mrps18-b, S18mt-b, 28S ribosomal protein S18-2, mitochondrial, MRP-S18-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHS2_CAMSI
Sequence: MVTVEEVRRAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGSDPIPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFQPLNITDWNSLFWIAHPGGPAILDQVELKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKSSAKKGLKTTGEGLDWGVLFGFGPGLTVETVVLHSVST
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 2, Naringenin-chalcone synthase 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: IRAD_SHIF8
Sequence: MMRQSLQAVLPEISGNKTSLLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ACIF2
Sequence: MSRMVQCVKLGHEAEGLDRPPYPGALGARIYQEVSKEAWQGWLKHQTMLINEYRLSPIDPKSRTFLEKQMEAYFFGDGAQSPEGYVPPAPQDS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: MENG_ROSS1
Sequence: MSTTVLPPPDKKAEYVERMFSRIAPGYDTMNGIITLGLDREWRATTVALAAPPSCGRALDIGTGTGDFLVELTAWMPDGLAVGVDFTVPMMRAGLPKIRDRRAVFVAGDALKLPFADESFDAITTGFTLRNVTDIAAAFREMWRVARVGATVACLEVARPRHPLLRAGHWFYFQRIVPLMARALGADPEAYTYLPQSARIFPPPEELAQIMRAAGWSDVTYRLVGLGAAAIHTGIKRG
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ATPG_ALISL
Sequence: MAGAKEIRSKIGSVKSTQKITKAMEMVAASKMRRSQESMAASRPYADTMRKVIGHLALGNLEYRHPYLEEREAKRVGYIIISSDRGLCGGLNINLFKKVMAGMKTWSEDGVEIDLAVIGSKATAFFNSYGGNVIAQNSGLGDKPSLEELIGTVGVMLKKYDEGQLDRLYVVNNKFINTMVQEPTIDQLLPLPKSEDEAMKRTHAWDYIYEPEPKPLLDALLIRYVESQVYQGVVENLACEHVARMIAMKAATDNAGDIIDELQLVYNKARQSAITQELSEIVSGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YCF4_PROMT
Sequence: MSSESKLSQSEKELSGLVLEQKIKGSRKVSNYLVASMLSIGGVGFLLASFSSYFGRDFLPLGNPSTLIFVPQGLVMGLYGVAAFLLAIYFWRLINIDYGSGVNRFDKNKGVLSLSRRGLFKNIEIEIPIDEIKAVKLEVREGFNPLRRVSLRIKGRKDLPISRVGSPQPLLDLENEGAEIARFLEVNLEGI
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FLIT_YERPB
Sequence: MERHQHLLSEYQQILTLSEQMLMLATVENWDALVDLEMAYLKAVENTANITISSCSSPVLQELLRQKLRSILENEIEIKRLLQRRLDKLSELVGQSTRQQAVNRTYGQFPDQALLLGETQ
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS10_CLOBJ
Sequence: MAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRAPHKYKDAREQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ACY1_DICDI
Sequence: MNSIQENEHVTVFREFLKIRTDHPTPDYESSTKFLVEKAKEYNIPYEVYRETGTPIVLMKIEGLEPNLKTVLLNSHVDVVPAVHDSWKVDPFSAWKDESGNIFGRGTQDMKCVCMQFLEVARRIVQSGQKLKRTLHLSFVPDEEIGGSGKGMEKFVYTEKFRQLNIGLCLDEGLASPTNDFTVFYGERAPWWVHITAVGNAGHGSRFIEGTAIEKLMRTINKMLAFRQEQFESLHHGQHECGKKLGDVTSLNLTVLKAGIPIDHSNNFSYNVIPTQAEAGFDIRIPPTVNLDQFLDQIKEWTAEEGLSFKFASYIPKNEMTKLDSDNKWWENFKESCKKMDINLVTEIFPAATDSRFIRNLGIPAFGFSPINNTPILLHDHNEFLNEKVYLRGIDIFMGIIPNLVNME
What is the function of this protein?
Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
What are the official names of this protein?
Aminoacylase-1, ACY-1, N-acyl-L-amino-acid amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD123_BOVIN
Sequence: MKKEHVLHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPAHSQPDSDDEAEEIQWSDDENTATLTAPEFPEFTTKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCMEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWDELLSGTNLKGDFSEEALEQDAPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD
What is the function of this protein?
Required for S phase entry of the cell cycle.
What are the official names of this protein?
Cell division cycle protein 123 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y069_MYCBP
Sequence: MVAPHEDPEDHVAPAAQRVRAGTLLLANTDLLEPTFRRSVIYIVEHNDGGTLGVVLNRPSETAVYNVLPQWAKLAAKPKTMFIGGPVKRDAALCLAVLRVGADPEGVPGLRHVAGRLVMVDLDADPEVLAAAVEGVRIYAGYSGWTIGQLEGEIERDDWIVLSALPSDVLVGPRADLWGQVLRRQPLPLSLLATHPIDLSRN
What are the official names of this protein?
UPF0301 protein BCG_0069.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MFD4A_HUMAN
Sequence: MGCDGRVSGLLRRNLQPTLTYWSVFFSFGLCIAFLGPTLLDLRCQTHSSLPQISWVFFSQQLCLLLGSALGGVFKRTLAQSLWALFTSSLAISLVFAVIPFCRDVKVLASVMALAGLAMGCIDTVANMQLVRMYQKDSAVFLQVLHFFVGFGALLSPLIADPFLSEANCLPANSTANTTSRGHLFHVSRVLGQHHVDAKPWSNQTFPGLTPKDGAGTRVSYAFWIMALINLPVPMAVLMLLSKERLLTCCPQRRPLLLSADELALETQPPEKEDASSLPPKFQSHLGHEDLFSCCQRKNLRGAPYSFFAIHITGALVLFMTDGLTGAYSAFVYSYAVEKPLSVGHKVAGYLPSLFWGFITLGRLLSIPISSRMKPATMVFINVVGVVVTFLVLLIFSYNVVFLFVGTASLGLFLSSTFPSMLAYTEDSLQYKGCATTVLVTGAGVGEMVLQMLVGSIFQAQGSYSFLVCGVIFGCLAFTFYILLLFFHRMHPGLPSVPTQDRSIGMENSECYQR
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 4A, Major facilitator superfamily domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TES_PIG
Sequence: MDLEAKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNISINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMNAQGPNRMCIPGGDRSTTSAVGAMEDKSAEHKTTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNDKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: RSMG_FLAPJ
Sequence: MEEILKHFPDLTNLQITQFEKLEALYQDWNAKINVISRKDIDELYTKHVLHSLAIAKIQKFEAGTYVLDVGTGGGFPGIPLAILFPETRFYLIDVILKKIKVVQAVAEALELKNVKAEQIRAENVKGDFDFIVSRAVTNMPDFVCWIKDKIKKTNKHELKNGILYLKGGDLTEELQDFPKAKEYNISEFFADDFFETKKVVHVPLKFKL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LICA_MYCCT
Sequence: MKMKITKGGTNVSYRIDNTFLQIKNYNSFNHQINYELLKDFDFVPKLISNDQKEIVWEYVEGNEPVVDLNNIKAITNQIKQLHNSNLNFPKNNLKQRVQYYRQKMVELNSGIEIIDKYANLIDDILDKMDHSTPLHNDLFPFNMIETKNKIYFVDWEYATMGDKHFELAYLIETSNMNSECEKVFLDLYSDYDSYKLLLNKIFVNYIVILWIRTQTSAPYNTTFFEQKIINYVTKLTN
What are the official names of this protein?
Protein LicA homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
Protein: RNP1_METVS
Sequence: MKFSQNILRHELVGLNLEIVNSTDKRLISTKGRVINETRNMLVIEKNNGKEITVPKEISIFRFEFSDLDTPKKVDIDGRLLIGRPEDRLKRKIKQLYPY
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_CERS5
Sequence: MLDHPLNSLGFAKPPSATRVVVAMSGGVDSSVVAAELAADGYDVVGVTLQLYDHGAALAKKGACCAGRDIHDARRVAETMGFPHYVLDYENTFREAVIDEFADAYLAGATPVPCIRCNERVKFKDLLQTAKDLDADCMATGHYIQRKMGAAGPELHCAADAARDQSYFLFSTTREQLDYLRFPLGHLASKAETRALAARHGLPVADKPDSQDICFVPNGNYAAVIEKLRPGAADPGEIVDLAGNVLGAHRGVIHYTIGQRRGLGIGGLGDPLFVVRLDPERRQVIVGPREALSTRIVPVREINWLGDAPLTSQAEWQVMAKVRSTRAPREAVIRPISDTEAEVELIAPEDGVSPGQACVFHVPGDSRILGGGWIWRGR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SALG2
Sequence: MIALIQRVTRASVTVEDEVTGEIGPGLLVLLGVEKEDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRAQALYEYFVERCRQQAIDTQTGRFAADMQVELVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPF_ECOLI
Sequence: MKHIPFFFAFFFTFP
What is the function of this protein?
This protein is involved in control of the biosynthesis of phenylalanine.
What are the official names of this protein?
phe operon leader peptide, phe operon attenuator peptide.
Protein: NTM1_DICDI
Sequence: MTIKNEEQQQQTNKLKYPKNLLSSGLDGEGNTYINIEDLWKKELEGKDNKMEDKWYKSADEYWKGVEATVDGMLGGLAQVSPIDVVASKVFIQDFIKGTDSRPPINLNLALDCGAGIGRVAKEFLLPIGFKNVDLVEQNKLFLDKAKSDNFKDDNRVENYYAVGLQDFTFEKKYDCIWIQWVIGHLHDLDFIEFLKKCMDSLTPNGIICIKDNCAKKRFIMDKEDNSVSRTEDHLKYLFDQAGCKLLKSMVQPNFPKELFPVLMFALERK
What is the function of this protein?
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved.  Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif (By similarity).
What are the official names of this protein?
Alpha N-terminal protein methyltransferase 1, X-Pro-Lys N-terminal protein methyltransferase 1, NTM1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. NTM1 family.
Protein: GTAX_DICDI
Sequence: MISSKLNNNYYNNPFTFNNNSNTISVTQKEALKKTIKEAAVLTDIALVNLNNDGPSLEISALIESKCKQLYEYSTTNTITIYNLLNYNNNNNYNNINRYNNNNSPSNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNINNNNNSNNNNINNNNNNNSENNCNNNFNVNKNLDNDKYNNKSCKNNNINNNNNNNNNSENKEKNNINNNNEKENNEYNNNRSASTSPVIKRSKSLSPILQFDKIDLEEEYTSDYDYSDGSNESSSPTLSASTLSSEDSKPKVLKRGRGRPSKPKPVQCFSCFRSNTPEWRKGKDKDGNVIDLCNACGLSYMKYIKKAKESKDKLSINNLINK
What are the official names of this protein?
GATA zinc finger domain-containing protein 24.
Protein: FACE1_HUMAN
Sequence: MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMDSETFEKSRLYQLDKSTFSFWSGLYSETEGTLILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVLNKDIQEDSGMEPRNEEEGNSEEIKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRKELFAAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSMWHYSHPPLLERLQALKTMKQH
What is the function of this protein?
Transmembrane metalloprotease whose catalytic activity is critical for processing lamin A/LMNA on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum (PubMed:33315887, PubMed:33293369).  Proteolytically removes the C-terminal three residues of farnesylated proteins (PubMed:33315887, PubMed:33293369).  Plays also an antiviral role independently of its protease activity by restricting enveloped RNA and DNA viruses, including influenza A, Zika, Ebola, Sindbis, vesicular stomatitis, cowpox, and vaccinia (PubMed:28246125, PubMed:28169297).  Mechanistically, controls IFITM antiviral pathway to hinder viruses from breaching the endosomal barrier by modulating membrane fluidity (PubMed:35283811).
What are the official names of this protein?
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: TRXB1_ARATH
Sequence: MNCVSRLKCLISKARSFARLGGESTLSQPPSLASAAFSSSAVMNGLETHNTRLCIVGSGPAAHTAAIYAARAELKPLLFEGWMANDIAPGGQLTTTTDVENFPGFPEGILGVELTDKFRKQSERFGTTIFTETVTKVDFSSKPFKLFTDSKAILADAVILATGAVAKRLSFVGSGEASGGFWNRGISACAVCDGAAPIFRNKPLAVIGGGDSAMEEANFLTKYGSKVYIIHRRDAFRASKIMQQRALSNPKIDVIWNSSVVEAYGDGERDVLGGLKVKNVVTGDVSDLKVSGLFFAIGHEPATKFLDGGVELDSDGYVVTKPGTTQTSVPGVFAAGDVQDKKYRQAITAAGTGCMAALDAEHYLQEIGSQQGKSD
What is the function of this protein?
NADPH-dependent thioredoxin-disulfide reductase that reduces thioredoxins O1, O2 and F3.
What are the official names of this protein?
Thioredoxin reductase 1, mitochondrial, NADPH-dependent thioredoxin reductase 1, NTR1, NADPH-dependent thioredoxin reductase B, AtNTRB.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RBL_CERS4
Sequence: MDTKTTEIKGKERYKAGVLKYAQMGYWDGDYVPKDTDVLALFRITPQEGVDPVEAAAAVAGESSTATWTVVWTDRLTACDSYRAKAYRVEPVPGTPGQYFCYVAYDLILFEEGSIANLTASIIGNVFSFKPLKAARLEDMRFPVAYVKTYKGPPTGIVGERERLDKFGKPLLGATTKPKLGLSGKNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLYVMEAVNLASAQTGEVKGHYLNITAGTMEEMYRRAEFAKSLGSVIVMVDLIIGYTAIQSISEWCRQNDMILHMHRAGHGTYTRQKNHGISFRVIAKWLRLAGVDHLHCGTAVGKLEGDPLTVQGYYNVCREPFNTVDLPRGIFFEQDWADLRKVMPVASGGIHAGQMHQLLSLFGDDVVLQFGGGTIGHPMGIQAGATANRVALEAMVLARNEGRNIDVEGPEILRAAAKWCKPLEAALDTWGNITFNYTSTDTSDFVPTASVAM
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.