PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_FRAP2
Sequence: MLIYLFNWLSHYYKGLEVFSSYVSVRIIMISITSLLITLFLGRPMIRWLQKMQIGQVVRDDGPQSHFSKRNTPTMGGVLILSSVIISALLWGSLSSIYLWILILVVIFFGAIGFFDDYLKLVLKHPKGLRAKHKFALQSIFSIILAIVLFYLLSKNGQMNLSIPFTKNLHIPMGIFLFVVLTFFIINGSSNAVNLTDGLDGLAIVPVVLVAAGLGIYAYIQTNSVLANYLLFPYINNQGLAEVAVFCAALCGSGLAFLWFNSHPAEVFMGDVGSLTLGAVLGVIAVMIRQELIFFIMGLLFVVEALSVMLQVGSYKLRNGKRIFKMAPIHHHFELMGWPETKVVIRFWIVSLILFLIGLVAIKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL017_YEAST
Sequence: MSCTASYAGMTTPVKDKEGHGIPCLQPIDVVECTYQYFTKSRNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNSLILDRGWFPPSFYTVHSKRTTRGA
What are the official names of this protein?
Putative truncated guanine nucleotide exchange factor YLL017W.
Protein: RL27_LACLA
Sequence: MLELNLQLFAHKKGGGSTSNGRDSQAKRLGAKASDGELVSGGSILFRQRGTHIHPGTNVGRGGDHTLFAKIEGTVKFEMKRGKKHVSVYPVVAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y671_MYCUA
Sequence: MADSSFDIVSKVDHQEVDNALNQAAKELATRFDFRGTDTKIAWKGDEAVELTSSTEERVKAAVDVFKEKLIRRDISMKAFDAGEPQASGKTYKVTGDIKQGISGDDAKKITKLVRDEGPKGVKTQIQGEEIRVTSKKRDDLQTVIAMLKQADLDVALQFVNYR
What are the official names of this protein?
UPF0234 protein MUL_0671.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: EFGM_PENRW
Sequence: MRSPSLARLQTRAVFGLTRSARFQPQTLLRQRCASTAAFRSAAVAPAYQSKLGQWDQRRNASAAASAVLEAAKVNPDGLSQTAIIDNLDPVEAARLDKCRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGRDSVGAKMDSMDLEREKGITIQSAATFCDWVKKDKEGVEQKYHLNLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGANPFKAVDQINNKLKMPAAAVQVPIGAEDEFEGVVDLIRMKALYNVGGSGEEIMEKDEIPEKVKAIAEERRTMLIETLADVDDEIAEIFLEELTPSEDQIRAAIRRATIGLKFTPVFMGSALANKSVQPMLDGVIDYLPNPAEVENLALDQKREEASVKLVPYNSLPFVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNSKKVKVPRIVRMHSNDMEEVSEIGAGEICAVFGIECASGDTFTDGTLGYSMSSMFVPEPVVSLSIKPKQSKDGANFSKAMARFQREDPTFRVSYDSESDQTIISGMGELHLDIYVERMRREYRVDCETGQPQVAYRETIGNRVEFDHLLKKQSGGPGEFARVMGYMEPTGALEENKFEQQVIGGSISEKFLYACEKGFNLSCEKGPLIGHKVLGTRMVINDGATHMTDSSEMSFKNATQQAFRKAFAESQPSVLEPLMKTVVTAPTEFQGDVIGLLNKRNATINDTETGVDEFTVHADCSLNGMFGFSSNLRAATQGKGEYTMEFSHYEKAPPHMQKELIAKYVKAQADRHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YR500_MIMIV
Sequence: MLMEQFLDYIGKLLFKIFMTIFPHAYKFYLTMWKIIFSLINCIKIVYYVDHQGEIMNVTHLYYLGIMRKTQGVFFLKLYDINGCHYMGFRGNINLIDNIQPINYDSYSRKTILFSHGGNSVNFQMECLDNYYNNCKLFDDSVQELVLILKMFNVKCTHISFISLKPFSRNNVEINDVKLTDLYNL
What are the official names of this protein?
Uncharacterized protein R500.
Protein: LPXB_FRATN
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSVGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRTKYRDKLGLKGNSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKSEIIKELIQEDCTVDNLFSELKRLFDDKQRNDYIVEEFEKIHKEMVIDTESKIIQVLNTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: GATC_STRPI
Sequence: MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEVDTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ZNTA_SHISS
Sequence: MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSSPTLSENVSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVESAVQKAGYSLRDEQAADEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATTLVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRARQGVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGCPCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLAMVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR
What is the function of this protein?
Confers resistance to zinc, cadmium and lead.  Couples the hydrolysis of ATP with the export of zinc, cadmium or lead.
What are the official names of this protein?
Zinc/cadmium/lead-transporting P-type ATPase, Zn(2+)/Cd(2+)/Pb(2+) export ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ETFB_RAT
Sequence: MAELRALVAVKRVIDFAVKIRVKPDKSGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEIIAVSCGPPQCQETIRTALAMGADRGIHVEVPGAEAENLGPLQVARVLAKLAEKEKVDLLFLGKQAIDDDCNQTGQMTAGLLDWPQGTFASQVTLEGDKVKVEREIDGGLETIRLKLPAVVTADLRLNEPRYATLPNIMKAKKKKIEVIKAGDLGVDLTSKVSVISVEEPPQRLAGVKVETTEDLVAKLKEVGRI
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase (PubMed:7334008).  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase.  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.  ETFB binds an AMP molecule that probably has a purely structural role (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit beta, Beta-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PABC_VIBHA
Sequence: MFWVNGLPQTHVPLGDRSFQYGDGCFSTIKTKKGQLEHWQAHVERMEACLTTLQIPFPDWRTVLDWAMSATLKDESAGIKIHISRGCGGRGYSPSGVEGPVVTISNFSFPAHYLAWQERGVQLGVCETRLGIQPLLAGHKHNNRIEQVLAKAEIDGTEFADAVTLNVQNHVIETTMANLFWVKDEKVFTPGLCLSGVAGVMRRKVLEYLQSEGYSVQVADFTLTDLLDADEVWMCNSLLGVAPVSGISAPENKIDFPIGKLTRRLQGNLNT
What is the function of this protein?
Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate.  Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate (By similarity).
What are the official names of this protein?
Aminodeoxychorismate lyase, 4-amino-4-deoxychorismate lyase, ADC lyase, ADCL.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: GLYA_MARMS
Sequence: MANTEAFFSQTLAERDPELFATITEEQERQETGIELIASENITSKAVLEAQGSVLTNKYAEGYPHRRYYGGCEAVDVTEQLAIDRAKKLFNCEFVNVQPHSGAQANGAVMLALLQPGDTIMGMSLSSGGHLTHGAAPAQSGKWFNAVQYEVSPETLLIDYDAIEAQALECKPKMIIAGGSAIPRQIDFKRFREIADKVGAYLFVDMAHIAGLVATGVHPSPLPHAHVVTTTTHKTLRGPRGGMILSNDLDLGKKINSAVFPGYQGGPLMHVIAGKAVAFGEALKPEFTDYIKQVVANAKALAEVMVERGCDIVTGGTDTHLMLVDLRPKGLKGNAADAALERAGITCNKNGIPFDTEKPMVTSGIRLGTPAATSRGFGIEEFQKVGHLISDVLDGLVEMPEGNPEVEARVLAEVRELCKRFPLYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NET4_PONAB
Sequence: MGSCARLLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGRKLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAHPHLAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIMMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNDEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDQPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQHCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRHCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISSHTDIDWHHEFPDFRPVHNKSEAAWEWEDAQGFSALLHSGKCECKEQTLGNAKAFCGMKYSYVLKIKILSAHDKGTHVEVNVKIKKVLKSTKLKIFRGKRTLYPESWTDRGCTCPILNPGLEYLVAGHEDVRTGKLIVNMKSFVQHWKPSLGRKVMDILKRECK
What is the function of this protein?
May play an important role in neural, kidney and vascular development.
What are the official names of this protein?
Netrin-4.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GPR37_HUMAN
Sequence: MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
What is the function of this protein?
Receptor for the neuroprotective and glioprotective factor prosaposin.  Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
What are the official names of this protein?
Prosaposin receptor GPR37, Endothelin B receptor-like protein 1, ETBR-LP-1, G-protein coupled receptor 37, Parkin-associated endothelin receptor-like receptor, PAELR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IDI2_STAA8
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMAYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRNLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRL22_ARATH
Sequence: MAGVVRLTTTSVQAIRVSSSFSSFATALNPLQPCLPPNSNLNSDKRLRLLSSSPSCSSSHYHPSSGLGSHLPLRRPKSQVVRVKVDENVAETEPPKWWERNAPNMVDIHSTEEFLSALSGAGERLVIVEFYGTWCASCRALFPKLCKTAVEHPDIVFLKVNFDENKPMCKSLNVRVLPFFHFYRGADGQLESFSCSLAKVKKAISVSPFPQLELGITLQTKRTTSLFFFDRIYQIL
What is the function of this protein?
Thiol-disulfide oxidoreductase that may participate in various redox reactions.  Possesses insulin disulfide bonds reducing activity.
What are the official names of this protein?
Thioredoxin-like 2-2, chloroplastic, Atypical cysteine/histidine-rich thioredoxin 2, AtACHT2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: HGD_BRADU
Sequence: MNINTSPDQIIRSSAQVTPGYMSGFGNSFETEALPGALPIGRNSPQRCAYGLYAEQLSGSPFTAPRGTNERSWLYRIRPSVKHSGRFEKADAGLWRSAPCHEYDLPIAQMRWDPTPVPKEEVTFVQGVQTMTTAGDVNTQAGMAAHVYLITKSMVDQHFYNADGELMFVLQQGNLRLVTEFGRIDAEPGEIVVIPRGVKFRVEIPNGPARGYLCENYGGAFTLPERGPIGANCLANARDFLTPVANYEDKDTPTELFVKWGGSLFKTTLPHSPIDVVAWHGNYAPYKYDLRTFSPVGAIGFDHPDPSIFTVLTSPSETAGTANIDFVIFPERWMVADNTFRPPWYHMNIMSEFMGLIYGVYDAKPQGFVPGGMSLHNCMLPHGPDRDAFEHASNGELKPVKLTGTMAFMFETRYPQRVTAHAANASTLQDDYADCWKGLEKRFDPNRP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: TAL_THEYD
Sequence: MKFFIDTANVDEIKKAWEVGVIDGVTTNPSLLAKEGKEPVSLLKEICQIVDGPVSAEAVSLKYEDMLKESIELSKIHSNIVIKIPMTEDGLKTVRKLSQEGIKTNVTLVFSPTQALLAAKAGATYVSPFVGRLDDISHFGMELVRDIQIIFENYGFDTEVIVASIRNPLHVLEAARIGADIATIPYSVIKQLIKHPLTDIGIERFLKDWEKLKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_LISMO
Sequence: MGYRKLGRTSSQRKALLRDLATDLIVFERIETTEARAKEIRKVVEKLITSGKKGDLHARRQAAAFIRHEVVEVVQVDAKGKDGSTVKKNRPVYALQKLFDDVAPRYAERQGGYTRILKKGPRRGDGAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RRP42_THEKO
Sequence: MSEMEVMASIMRDHIIELLREGKRIDGRSFEDYRDLEIKVNVIEKAEGSAWVRLGDTQVLVGIKAELGEPFPDLPDRGVITTNVELVPLASPTFEPGPPDENAIELARVVDRGIRESQAVDLEKLVIVPGKLVRVIFIDVHVLDHGGNLLDASGIGAIAALLSTKLPKVNYNEETGEVEILDEYEPLPVNHVPIPVTFAKIGNSIVVDPSLDEERVMDGRLTITTDETGHISAAQKGEAGAFKMEEVMYALEVALKKGNEIREKVLKAVGRA
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Contributes to the structuring of the Rrp41 active site.
What are the official names of this protein?
Exosome complex component Rrp42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK3_NAMOO
Sequence: DPPFSPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-3, PK-3, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDIA1_CRIGR
Sequence: MLSRSLLCLALAWVARVGADAPEEEDNVLVLKKSNFAEALAAHNYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAETLIDSSEVAVIGFFKDVESDSAKQFLLAAEAVDDIPFGITSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLGNFKKAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPATADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDVDLEEALEPDMEEDDDQKAVKDEL
What is the function of this protein?
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds.  At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell.  May therefore cause structural modifications of exofacial proteins.  Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins.  At high concentrations and following phosphorylation by FAM20C, functions as a chaperone that inhibits aggregation of misfolded proteins.  At low concentrations, facilitates aggregation (anti-chaperone activity).  May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis.  Also acts as a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.  Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
What are the official names of this protein?
Protein disulfide-isomerase, PDI, Prolyl 4-hydroxylase subunit beta, p58.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein. Note=Highly abundant. In some cell types, seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources. Localizes near CD4-enriched regions on lymphoid cell surfaces. Colocalizes with MTTP in the endoplasmic reticulum.
Protein: ARP2_ORYSI
Sequence: MDSGNVVVCDNGTGYVKCGFAGENFPTSVFPCVVGRPLLRYEESLQEQELTDIVVGAACADLRHQLDVSYPVTNGIVQSWDDMGHIWDHAFYSELKVDPSECKILLTDPPLNPVKNREKMIETMFEKYNFAGVFIQVQAVLSLYAQGLLTGLVIDSGDGVTHVVPVVDGFSYPHITKRMNVAGRHITSYLVDLLSRRGYAMNKSADFETVREIKEKLCYLSYDYKREYQLGLETTILVKSYTLPDGRVIKVGTERFQAPEALFTPELIDVEGDGMADMAFRCIQEMDIDNRMTLYQHIVLSGGSTMYPGLPSRLEKEMLDRYLDVVLKGNKDGLKKLRLRIEDPPRRKHMVYLGGAVLAGIMKDAPEFWITRQEYQEEGLACLRKCGQA
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament.  Regulates the directionality of cell expansion by regulating the actin organization, and thus the microtubules distribution and the fusion of small vacuoles (By similarity).
What are the official names of this protein?
Actin-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CNPD1_HUMAN
Sequence: MDLTGLLLDEEGTFSLAGFQDFTFLPGHQKLSARIRRRLYYGWDWEADCSLEELSSPVADIAVELLQKAAPSPIRRLQKKYVAHVSREACISPCAMMLALVYIERLRHRNPDYLQHVSSSDLFLISMMVASKYLYDEGEEEEVFNDEWGAAGGVAVPTLNALERGFLSAMDWHLYTDPREIFEVLSWLESCVAEQQGRWRGWYTYTDLCVLLEQPTWQLALGSLCQRLVKLSCLLAVAYVSSVALAVASVAVIHQSLGLSCIPTPGPPDLGLTSRCLLEPCIPSVPQCLPSLANVSSCLEGSMGLRSLWGSLLASLTPPPLPPPDPPAPPTLLHNCHLCQKLQRDSPTCHACLHPNRTVPTALSSPWYHTYGLAPPWPWSPVLLSLPQPQQCSLFSVMELARLKSFVFPG
What are the official names of this protein?
Protein CNPPD1, Cyclin Pas1/PHO80 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CNPPD1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL18_LEIXX
Sequence: MALLGTRGKSKAAARGRRHTRLRKKIVGTELRPRLVVTRSARHVFVQVVDDAQGRTLASASTMEADLRGFDGDKTAKARKVGELVAERAKSAGVEAVVFDRGGSQYAGRVAAVAEGAREGGLNL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: AQP6_LACBS
Sequence: MDDKFDDDALPNSKTTPEDYGDKLAEYDYTNTFPNTWMRLREPFREYIAEFVGVAVLIIFGVGADCQVVLSANTGVAPSPKGDYLSLNCGWAIGTAMGVWISGGISGGHINPAVTLALMAWRGFPWWKVPGFIFAQLLGGIVGAGLVYVNYIHAIDIVEGGRHIRTLDTAGLFATYAADYMTNVSCFFSEFLATAVLIVVIHAMNDKRNAPPPAGLAPLVLFFLILGIGASLGMETGYAINPARDLGPRMLTAMVGYGRQVFAFRNQYWIWCPVIAPFLGAQVGTIFYDLFFYKGQDNVFGRLGSHIHISPA
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes (PubMed:21352231).  In addition to water, shows also strong glycerol and ammonium transport activities (PubMed:21352231).  May be involved in fungal nitrogen (ammonium) support of the plant host in symbiosis (PubMed:21352231).  Glycerol accumulation has never been observed in ectomycorrhizal (ECM) fungi, therefore, glycerol permeability of Lacbi1:391485 might be a relict of the affiliation of the protein to the group of aquaglyceroporins, and other osmotic active compounds (e. g.  trehalose or mannitol) may have taken over glycerol function in ECM fungi (Probable).
What are the official names of this protein?
Aquaporin Lacbi1:391485.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: RECF_SYNE7
Sequence: MFLHSLHLQHFRNYRDQTVQFQAPKTILLGENAQGKTNLLEAVELFSTLRSHRVSRDRDLVQTGAESALLTAVVERDSGEQQLQIQLQQQGRRRVQRDGEVLRRQLDLLGSLCSVQFSSLDLDLVRGGPQQRRDWLDRLLIQLQPIYAHLQQQYGRVLRQRNALLRRAESLDLALLAPLNWQLAQLGVHIMRRRSRAIQRLVPLAAHWHREISGQREQLIVAYQPSVLAPDDTDEAIAWQERMLAQIEARRAAELGQRTSLVGPHRDDLNLSINGTEARLQASQGQQRTLVLSLKLAELELIEAVLGEPPLLLLDDVLAELDLRRQQQLLEAIANRFQTLITTTHLSAFDQSWVETAQILTVQSGHLQSEAVPMAPSSASLHKSLDS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOC4_SAIBB
Sequence: MSLLRHSLQALPLLCLCVLVLACIGACQSEAYEGTPSPPPEQKKSHWNLVQSRMKEFLEPAVTRTRDRWQWLWSLSALRGFMQTYYDDHLRDLGPRTKTWLLESKDSLLNKTYSLCPRLLCADKK
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.