PharMolix/UniProtQA huggingface dataset:
Protein: SELO_SHEPA
Sequence: MRLKQDFFEQLPEFYSQVFPLGISNPHWLAWSQDAADLIEIKQPSDELLQGLSGNAHVDGASYYAQVYSGHQFGGYSPQLGDGRSIILGEALGPQGAWDVALKGAGPTPYSRHGDGRAVMRSAVREFLISEALHHLHIPTTRALAVIGSDLPVWRESQETAAITVRLAKSHIRFGHFEYFCHSERGAPAKLKQLLDFTIKQHYPDLSCDAVGYKAWFTRVVADTAKMIANWQAIGFAHGVMNTDNMSILGDTFDFGPFAFLDTFKEGFICNHSDPEGRYAFGQQPGIGLWNLQRLAQALSPIIASDDLIESLNQYQVELVKHYLLLMRGKLGLKTSAAEAEQDDHDLALIGAFTGLMERNQLDHTNTWRRFGQLDPNASHSSLRDDFVDLHGFDTWYQAYQVRLGSVDEVGLWQKERNQVNPKYILRNYLAQEAIIAVELGDLKPLHNLQRLLQNPFDEQLEFEDMAKRPPDWGQGLIMSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ATG5_KLUMD
Sequence: MEELRERVWNGTINVEVVVSDAIVVPNTTLADKSCHIVMLRDAYLGFYLPTVVRKLADTIKVPYESDYRNWWFEYNGEGVPWEYPCGVLFDLLNKKRKKQGNELDDTSLQMWELQLCHGDKYPRGILPLVDGHSQIKDYWRHQWKQACFILNGSAKRIMSLSIPDFENFWVSILSRNRSDFMAVRSKLFSMNKAKSLPVRVWTSNYAVLQPTVPVTDKELSVAELLDSIKLSSDGVKSVIIQGIDVSIEDNIFELYDIFASIDGFLYLVTK
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation (PubMed:26442587).  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) (By similarity).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production (By similarity).  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (PubMed:22682742).  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).  ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E2 activity (By similarity).
What are the official names of this protein?
Autophagy-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Note=Localizes to the isolation membrane (IM), a membrane sac which is generated from the pre- autophagosomal structure (PAS) (By similarity). Ultimately, the IM expands to become a mature autophagosome (By similarity). Localizes also to a dot at the junction between the IM and the vacuolar membrane, termed the vacuole-IM contact site (VICS) (By similarity). Correct localization to the PAS requires ATG21 (By similarity).
Protein: LTG27_ARATH
Sequence: MAYTNKVAVAVGAAVVFLAVVMNPRWTEAQTYPKLDRLCVMMIPDILEECFTHDRLKPTEDCCNDLKNATMTQVDCLCDNFLESLSFSDLSRTFSAGVLKKCDVSHKYMCQAAKNRGEAKGGRNSTTTCDNSITNTSVGGKNKVATSMSAFGLVAILLFVMF
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 27, AtLTPG-27, Protein LTP-GPI-ANCHORED 27.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CFA61_TETTS
Sequence: MYSNNQLDNPNHSRSQYRNGDQSGIYAGSDEEFQVLVRKSDLDDVDEVLKIIAQHEREANDLLYDYPNLLSLFEKNYLSVTILNQQQQIIGAAVFNDFPQGLTGQIDFQHENFWENWIFDAFNFDESICITPFNTLWMTFFFVAKDQYKFSQEEELIICQKVFQNVYATLPQLEGILFLKRGETMEDNGAQAQISSILENIFIEVPVKDRDIIKRVRGIHLNSEVFYSPKHACQEIIEIRMAREQDHDDLAEIFNRQSEVLTAQFGEFFIADLIATQNLTRRGTRKFLNNGKAIVGQVRDKAVGLMSISTDIDYKFLAQCFELETYDNLFKPDFMEAIQNKRDDIRRENQYREEDQYQEIVKKMNEERMKSHFIGQRMTLQQHCREKEQEIVMKIDEIINNDAIQKNLTKKQVEEFLDEWLRGYELHQPSDLFYQYPHIFPNTQSIILTPRQLLIETLEFFGLPQHYMNGAGHWKDWVQKKMEEKRIAQLKRPQKKVTKRPKRQKEEDKKEDEFKPPSYFDLTPFQSAFKKFLAVNPEGRTIFRQKIEASMKVIKMMFCNENGEMKEERHVDLNDLGNELNKQKMDIAPEVCENLASFLECFGEIKYEEEIIMVNPPKEDTNQNAKIAQTKKMFASEQTESKPIPKLLKKTSFQEFFDAVYKMKEFDIMMNRLDITKSTTLKAEVSQIVKEEAQQEKAKQEKRRIERSPNPYDDYVKNLKDLDSIPEVPIDAQNAIVINLFCIDENFESRSLDFVEYAFSIFGDRDYIILTQPFTVPETTLLQQFIKIPMKKNSTFDHVLYIYHKDCLLSNTLFIRKSKLEDMQYVAPLFSNLINKQQIYDDTLEAITQTASRKVAFSVFCDQSLIGIYVVSKNVNLDYYISHFCVQDHIILKEHPMTCHTKLIHTALNPLFTKNTRFILKEILRLMNKTCMYFEVQEKTLLPDVFNELVFVRARQFPHFLKRKWDFEHDKEHFERAGDLTEVQDGKRDAFDQEQAPFSLSVITKKMMSSVKVNNNTRIVVVGASDTGISFIESLLSVKDINFTHITLLAPGGIMTMHINLPGDQLKALSTNYTLEELKNLMLDARVNVLDAKMVELDKKGKKIKLDKNAELPYDYLVNTVGLIDTELQNRRLISTGLFSSPYYQQLLDKYGRDRAQIEEGAPPIFGQHPVYGNYVQGVYSIDDPYLYEEFKKTGKKDSNIDLLTRKKRPQSITIYGRTLHTIAFISGMVNRGVHPNRIHYVIPPKVFETQVQFKNNTERLIYEDKRINDPDPFDDPSVEQKIFEFMESKGIQVHKGYNLHQIDVDEETRICQGVVFRKKADNYEEIIQQIEIKKQQILERDANSENADKGFDDTQSRDGDEENQPITLEQEIEELERNKFDDIEITSRFLVTSGLVDIDKEIFYIIHENGLVYNGRLIVKSNFQTTEKDIFCCGKICEFSQRYKRLSIGRSLRLDKYNGRELGQKLAKCLLDSLDLGYLTDQIYSLGELPNLYMPIGIGAFLPGDLFYYHIKKNDYARPSKTMEAEDNRQDIVSDNIDQKQQIGHYIKFKFDNNGIIDQVTYLGTEPVSVQSLVSFVGLSEKCLNQLDVRFKNGLIPNISEFLSENWAIGLYHEWFSEFRHITKMEMLQSENIQQILDEAAKYAQGGGFLDPEFIEKIKAKISPEIISQIQQGTLDFIRENQNHLPMYYVPPKKVNVD
What is the function of this protein?
As component of a spoke-associated complex, regulates ciliary mobility by mediating a stable and functional assembly of the radial spoke 3 (RS3).
What are the official names of this protein?
Cilia- and flagella-associated protein 61, CFAP61, Flagellar-associated protein 61.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: FADA_PSESM
Sequence: MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNNKVDPAEVEDVIWGCVNQTLEQGWNIARMASLLTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTNNGDVFVIGGVEHMGHVSMMHGVDPNPHMSLHAAKASGMMGLTAEMLGKMHGITREQQDAFGLRSHQLAHKATLEGKFKDEIIPMQGYDENGFLRVFDYDETIRPDTTLESLAALKPAFNPKGGTVTAGTSSQITDGASCMIVMSAQRAQDLGIQPLAVIRSMAVAGVDPAIMGYGPVPATQKALKRAGLSISDIDFFELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARISGTLLNVMKQNGGTFGVSTMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_SALTY
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: TOPZ1_GORGO
Sequence: MRRPPPLGPTTASGPEGNVRNLQKRQAPGPGAAGGCGPEAGGRRENKQKRRMVARATPGRGEVESDKSVAASGAGKAARRRVEGRRGQVSPSDSSDPRGLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVECLQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAENFSKKENLRSLAEKSDTNSIPQLLQTEENVMEVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSPLNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETESTSEPLGYESMASKEDFKSMKSFIGKSPNEYHIERRSSREDLRSASEELNLSCQRTIPMTGKRTWPCYSCARISAWCWKKASLPESSYFFPGSQESYRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRSGSEVISNTTEDTQLTSETQSLTGNKKKARGNLMKLNLTATSKDGQEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKTEKRKEVNAKSSEREAYSPLELLDNLSGADIRQNRSKENVSMTMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRKITKNFSEVGFPDILKAYEDDILLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKHDPKDVNTSLGEVANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADIMVGECQFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNGTICFLNEILLAFGNIETRRFFYQKQKTIKVFQKSLGLMIPYKYCKFHFNTLRGCERPLCKFAHVPEQGDEKVCMDVFKKYININELCLLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLKILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLQMRQFKKNWKCDLHSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFCACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMCFYHKLLQWSKGRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWIINTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSPGTSTQILQIVLKRCEDNQSRSSDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENMKWAGKVWLFSNH
What is the function of this protein?
Important for normal spermatogenesis and male fertility.  Specifically required for progression to the post-meiotic stages of spermatocyte development.  Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.
What are the official names of this protein?
Protein TOPAZ1, Testis- and ovary-specific PAZ domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DTD_SHESR
Sequence: MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENGKMNLNLTQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQALGLYEEFVAFCRAQGVTTETGQFGADMKVELVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_THEVB
Sequence: MKGLEKIIPLDGRDIKVVLQKFAPQAAGSILISSGETAVLVTANRAAAREGIDFLPLVVDYEERLYAAGRIPGGFLRREGRPPEKAILIGRLIDRPLRPLFPQWLRDDLQVVATTVSLDENAPPDVLAVTGASIAVLLAQIPFNGPMAAVRVGLVGDEFVINPTYKEIERGGLDLVVAGSPDGVVMVEAGANELPEADMIEAIDFAYEVIRDLIQAQRDLLKELGIDIVRAEPPAIDPTLENFIYDRAAEPVKAILKRFEKDKNVRDAALDEVQGAIAQEIAALPEDDPVAVAAAENPKALPTLFKAVTKKLMRQQIIEEGVRVDGRRLDEVRPIWCEVGVLPERVHGSALFNRGLTQVMSVTTLGSPADAQALDDLHPEDSKRYLHHYNFPPYSVGEVKPLRSPGRREIGHGALAERALEPVLPPKEEFPYVIRVVSEVLSSDGSTSMGSVCGSTLSLMDAGVPIRKPVSGAAMGLIKEGNEVRILTDIQGIEDFLGDMDFKVAGTDSGITALQMDMKITGLPVAVIQQAIEQARPARLHILEKMLAVLDKPRPQLPPSAPRLLTLQIPPDMIGLVIGPGGKTVRGISEQYNVKVDISEEGLVTITAPNETNAKQARAAIEGLTRKLNAGDVYLGRVTRIIPIGAFVELLPGKEGMIHISQLAEYRVGKVEDEVKIGDEIVVKIREVDSKGRINLTRLGIHPDEAEAARSNSVV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTHL_ARATH
Sequence: MAMEIGEDEWKVCCGSSEFAKQMSTSGPLTSQEAIYTARDIWFNQVNVTDWLEAFSAHPQIGNTPSPSINSDFARRSVSEQSTAFATTSASALQELAEWNVLYKKKFGFIFIICASGRTHAEMLHALKERYENRPIVELEIAAMEQMKITELRMAKLFSDKAKVISETDSSSSPVSTKPQDRLRIIGGHLNVAAEAKAPKRSRPPITTHVLDVSRGAPAAGVEVHLEVWSGTTGPSFVHGGGGVWSSVGTSATDRDGRSGPLMDLVDALNPGTYRISFDTAKYSPGCFFPYVSIVFQVTESQKWEHFHVPLLLAPFSFSTYRGS
What is the function of this protein?
Involved in the last two steps of the degradation of uric acid, i. e.  the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) and its stereoselective decarboxylation to (S)-allantoin.  Might function as a negative regulator to modulate brassinosteroid-mediated plant growth.
What are the official names of this protein?
Uric acid degradation bifunctional protein TTL, Transthyretin-like protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Peroxisome.
Protein: Y899_MYCBO
Sequence: MKRGVATLPVILVILLSVAAGAGAWLLVRGHGPQQPEISAYSHGHLTRVGPYLYCNVVDLDDCQTPQAQGELPVSERYPVQLSVPEVISRAPWRLLQVYQDPANTTSTLFRPDTRLAVTIPTVDPQRGRLTGIVVQLLTLVVDHSGELRDVPHAEWSVRLIF
What are the official names of this protein?
Uncharacterized protein Mb0899c.
Protein: YPI1_KLULA
Sequence: MSEGPSALPEGTHTVTVTEVPQLLQLRAGQNEKNKTKKKDTKSKVRWDEKVIDNENMNKKKTKICCIFHPNTPLESDEEEEGECEHDHNHGHDSSSSSSSSSSDEDEGKSFDERRKARLERRRKKLEQKRPPSPNAYEVQPDYSAYRDKNRKDAQ
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXA_HAEDU
Sequence: MRLIDSTAKISPLAVIEDGAQIGAHVEIGPFCVIGKNVKIDAKTILHSHVVINGHTEIGEQNQIFQFASIGEINQDLKYQGEPTKVVIGDRNSIRESVTIHRGTVQGGGVTRIGNDNLFMINAHIAHDCNISNHCIIANNGTLAGHVRLDDFVIVGGMSAIHQFVIIGSHVMLGGGSMVSQDVPPYVMAQGNHAQPFGVNLEGLKRRGFDKPTMHAIRHVYKLIYRSGKTIEEVLPEIEHIALNEPAIKVYLDFFKHSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_BACCR
Sequence: MKVIFLKDVKGKGKKGEVKNVPDGYANNFLLKQGLAAEATNSSMKTLEAQKRKEEKDAAAELENAKELKETLEKLTVELKAKSGEGGRLFGSITSKQIVDAMQKSHKIKLDKRKFEMDDAIRALGYTNVTVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SYDND_BRUC2
Sequence: MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQYDLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCAS_MYCBO
Sequence: MESRVTPVAVIGMGCRLPGGINSPDKLWESLLRGDDLVTEIPPDRWDADDYYDPEPGVPGRSVSRWGGFLDDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSSTAVFTGLTHEDYLVLTTTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGMLSSTGRCHSFDADADGFVRSEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGRTETLTMPSEDAQVAVYRAALAAAGVQPETVGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRHGVVPPLLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGTNVHAIVEEAPAEASAPESSPGDAEVGPRLFMLSSTSSDALRQTARQLATWVEEHQDCVAASDLAYTLARGRAHRPVRTAVVAANLPELVEGLREVADGDALYDAAVGHGDRGPVWVFSGQGSQWAAMGTQLLASEPVFAATIAKLEPVIAAESGFSVTEAITAQQTVTGIDKVQPAVFAVQVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSKLMTRIAGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTSDTVRDLIARWEQRDVMAREVAVDVASHSPQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREQPVCDGAYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLPHGLRGLLTELHRAGAALDYSALYPAGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITVHPLLGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALAAAAEVFGEAAEVRDITFEQMLLLDEQTPIDAVASIDAPGVVNFTVETNRDGETTRHATAALRAAEDDCPPPGYDITALLQAHPHAVNGTAMRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVALPASIRFQQGAYRIHPALLDACFQSVGAGVQAGTATGGLLLPLGVRSLRAYGPTRNARYCYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDRLVSERLLTLGWQQRALPEVGDGEAGSWLLIDTSNAVDTPDMLASTLTDALKSHGPQGTECASLSWSVQDTPPNDQAGLEKLGSQLRGRDGVVIVYGPRVGDPDEHSLLAGREQVRHLVRITRELAEFEGELPRLFVVTRQAQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQVRRPGDLQTLEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIIDDREPQLGMDFVGVVTAVGEGVTGHQVGDRVGGFSEGGCWRTFLTCDANLAVTLPPGLTDEQAITAATAHATAWYGLNDLAQIKAGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSVEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFKLTADGVLTAPQCTHYPLAEAADAIRAMSNAEHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSYIITGGLGGLGLFFASKLAAAGCGRIVLTARSQPNPKARQTIEGLRAAGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSPKVFGSWNLHRATLGQPLDWFCLFSSGAALLGSPGQGAYAAANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPEEGAYAFETLVRHDRAYSGYIPILGAPWLADLVRRSPWGEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRRLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHVETETGIRLTPKVIATNNTARALAQYLADTLAEEQAAAPAAS
What is the function of this protein?
Catalyzes the elongation of long-chain fatty acyl-CoA with 3 or 4 methylmalonyl-CoA (not malonyl-CoA) as the elongating agent to form tri- or tetramethylated-branched fatty acids known as mycocerosyl lipids.
What are the official names of this protein?
Mycocerosic acid synthase.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL18_NEIMB
Sequence: MDKHTTRLRRARKTRARIADLKMVRLCVFRSNNHIYAQVISAEGDKVLAQASTLEAEVRGSLKSGSNVEAAAIVGKRIAEKAKAAGVEKVAFDRSGFQYHGRVKALAEAARENGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IL17_RAT
Sequence: MCLMLLLLLNLEATVKAAVLIPQSSVCPNAEANNFLQNVKVNLKVINSLSSKASSRRPSDYLNRSTSPWTLSRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPEKCPFTFRVEKMLVGVGCTCVSSIVRHAS
What is the function of this protein?
Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity.  Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter.  This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.  Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi.  As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites.  In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines.  In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells.  Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance.  Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation.  Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection.  Upon acute injury, has a direct role in epithelial barrier formation by regulating OCLN localization and tight junction biogenesis.  As part of the mucosal immune response induced by commensal bacteria, enhances host's ability to resist pathogenic bacterial and fungal infections by promoting neutrophil recruitment and antimicrobial peptides release.  In synergy with IL17F, mediates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers.  Involved in antiviral host defense through various mechanisms.
What are the official names of this protein?
Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN185_MOUSE
Sequence: MTTEDYKKLAPYNIRRSSISGTEEEEVPFTPDEQKRRSQAALGVLRKTAPREHSYVLSAAKKTTSSPTQELQSPFLAKRVDVVDEDVLPEKNQEPPALARPDSGLSSSTTEKIAHRQITPPTAELHLVAPDLEALSTPDSCEENNAAPKIIKEIPGTLQDGQSDPTVASQQLADLSILEPLGSPSGAEQQIKAEDCTNMLMSPSSCMVTVTVSDTSEQSQLCVPGVSSKVDSSSTIKGILFVKEYMNTSEVSSGKPVSSHCDSPSSIEDSLDLAKKPPHEGTPSERPTEGVCTYCSHEIQDCPKITLEHLGICCHEYCFKCGICNKPMGDLLDQIFIHRDTIHCGKCYEKLF
What is the function of this protein?
May be involved in the regulation of cellular proliferation and/or differentiation.
What are the official names of this protein?
Zinc finger protein 185, LIM domain protein Zfp185, P1-A.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion.
Protein: V162_FOWPN
Sequence: MVIYCNLHTVIMNIFYNNIHRCFKDTPLHKAVMLPDAVERIRMFVSKGADINVISDFKKTALHYAAKKLATPEVLKTLIYLGTNVNVTDMFESTPLHYAVQENGLEATKKLLDLGADPNTKYMNGQTPLHCAAMVIPDGPELVRILVEYGANVNALDNKHNTPLALAAELSNTNKTIETLIELGADVKIKNNDGITPLHLAAKSSSDSKTVETLILHGADVNATCSEGNTPLHDAATSYELSNTIEMLIEYGAEVNAANSVGDTPLHCAARSRNPVHKLKTLIAHGSNVNAVNGISVTPLHLATYSDNATEALKVLIEHGAEVNSVDIYGRTPMHYISRSYSSQSLKTAVELLVEHGADIEAKNVIGGTPLSSACNNIEYDLRLIECFIEYGADINTRDIRDETPLYSAIKYPEIVNLLMNYSASTNITNKSNITPLESAIANCIGSAEIIVTQIILDAFRFPDIKNDAIFIRNMKTIEECTMLIDVKESCEYDINKMRSIKFNNMYGLDIFIRSNNINLLSSLVSNVEDIYLEPGCFLVYGNKLRKSVYAARKRLSLLKNSISILSNITTDGYWNALPIELKYNILAMLGDNDLFNIVRNCS
What are the official names of this protein?
Putative ankyrin repeat protein FPV162.
Protein: AROK_BRUC2
Sequence: MSGTNKQTNLHRQTETIRQLLGSKVVVLVGLMGAGKSTIGRKVANMLNLPFKDADTEIETVSRMTVAELFEAYGEVEFRDLERRVILRLLDDGPMVLATGGGAYMNAETRAAIAEAGISIWINADLDVLMERVSRRQNRPLLRNSDPRGVMQRLMDERYPVYALAELHLMTRDEKKEVIAAELIEVLAAHLEKEQAASAG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUC1_RAT
Sequence: SASPGLPKGEKEQQEAIEHIDE
What is the function of this protein?
Has a role in the physiological regulation of fucosylation processes.
What are the official names of this protein?
Fuctinin-1, Fucosyltransferase inhibitor 1.
What is the protein family that this protein belongs to?
To human SET/PHAPII protein.
What are the subcellular locations of this protein?
Cytoplasm.