PharMolix/UniProtQA huggingface dataset:
Protein: ACT_CARMA
Sequence: KCDVDIRK
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HRCA_STAA1
Sequence: MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: COX1_DICCI
Sequence: MKLLEIYDKQLVEQEEGGFRAILTRYLNKWIFTVDHKLIGTMYITFSIFAGIIGTLLSLVIPMELSTGNMLEGDSQQYNVIVTAHGLIMIFFVVMYCSMPAMLGGFANWFLPIMVGAPDVAFPRLNNISLWLIVVSFGLLLTSSCVGIGAGTGWTVYPPLSMMEYHPGHAVDVGILSLHIAGASSLVGAINFLTTVFNMKIAGLSWPKVSLFVWSVVITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFHPEVYILILPGFGIISIIISRYSNKGIFGVKGMISAMSAIGFLGFLVWAYHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYAIMNSNRILGIVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFFVNIFTPYFKKKALISKKFQRGAMILMGLDFSRDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFAYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNSSNLVEFDSYMVYERDLNEGQLRLLEVDNSMIVPVKTHIRLIITSGDVLHSWAVPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVEAVKVQEYLGRLYK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1+2, Cytochrome c oxidase polypeptide I+II.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIS_SHEPC
Sequence: MFDQTTNTEVHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQLDGQEAQEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: ALR_AZOSB
Sequence: MRPATALIDLDALRHNYRLARSRHGGRALAVVKANAYGHGAVRCAQALAAEADGFAVAFLDEALELRAAGITQTIVLLEGVFDAAELEQVVAHGLWPVVHHAAQIEMIEQAALARPLDIWLKVNSGMNRAGFVGDAVGSAWQRLRASGKVGEITLMTHFARADEPQVIATAEQLADFDTATRGLPGPRSLANSAAVLGWPDAHADWARPGILLYGADPMPGEGNGLQPVMTLESGVIAVRDLAAGAPLGYGARYVAERPRRIGLVAMGYADGYPRSAPDGTPVVVDGQPSMLVGRVSMDMLTVDLTDLPQAGIGSRVELWGRQVPINQVAAGAGTIAYELLCNVKRVVFRYRG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: SPIKE_IBVB
Sequence: MLVTPLLLVTLLCALCSAVLYDSSSYVYYYQSAFRPPSGWHLQGGAYAVVNISSEFNNAGSSSGCTVGIIHGGRVVNASSIAMTAPSSGMAWSSSQFCTAHCNFSDTTVFVTHCYKHGGCPLTGMLQQNLIRVSAMKNGQLFYNLTVSVAKYPTFRSFQCVNNLTSVYLNGDLVYTSNETIDVTSAGVYFKAGGPITYKVMREVKALAYFVNGTAQDVILCDGSPRGLLACQYNTGNFSDGFYPFTNSSLVKQKFIVYRENSVNTTCTLHNFIFHNETGANPNPSGVQNIQTYQTKTAQSGYYNFNFSFLSSFVYKESNFMYGSYHPSCKFRLETINNGLWFNSLSVSIAYGPLQGGCKQSVFKGRATCCYAYSYGGPSLCKGVYSGELDHNFECGLLVYVTKSGGSRIQTATEPPVITQNNYNNITLNTCVDYNIYGRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQLLENQFYIKITNGTRRFRRSITENVANCPYVSYGKFCIKPDGSIATIVPKQLEQFVAPLFNVTENVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGSSLDCRKLFQQYGPVCDNILSVVNSVGQKEDMELLNFYSSTKPAGFNTPVLSNVSTGEFNISLLLTNPSSRRKRSLIEDLLFTSVESVGLPTNDAYKNCTAGPLGFFKDLACAREYNGLLVLPPIITAEMQALYTSSLVASMAFGGITAAGAIPFATQLQARINHLGITQSLLLKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVSKQSAILTETMASLNKNFGAISSVIQEIYQQFDAIQANAQVDRLITGRLSSLSVLASAKQAEYIRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFSYTPDSFVNVTAIVGFCVKPANASQYAIVPANGRGIFIQVNGSYYITARDMYMPRAITAGDVVTLTSCQANYVSVNKTVITTFVDNDDFDFNDELSKWWNDTKHELPDFDKFNYTVPILDIDSEIDRIQGVIQGLNDSLIDLEKLSILKTYIKWPWYVWLAIAFATIIFILILGWVFFMTGCCGCCCGCFGIMPLMSKCGKKSSYYTTFDNDVVTEQYRPKKSV
What is the function of this protein?
Acts as a viral fusion peptide after S2 cleavage occurring upon virus endocytosis.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses spike protein family.
What are the subcellular locations of this protein?
[Spike protein S2]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers may be transported to the plasma membrane, where they may mediate cell-cell fusion. SUBCELLULAR LOCATION: [Spike protein S1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers may be transported to the plasma membrane, where they may mediate cell-cell fusion. S1 is not anchored to the viral envelope, but associates with the extravirion surface through its binding to S2.
Protein: BSC2_ALTBR
Sequence: MESAQIHSTRDSLFILWLTTLLVSVLATAAYIKFQSRPRPYSGFPLVTLGGPSETDSSHAANWFRRGRALVNKGLSELSGAFQISNGSGYWIILPSKYMDELRNHPDMSLRDALREENFPNYRGFDGFRQAFKDSTFTQEVIRVKVTQSLGLITANLANECQHALQENLGESREWQQRFIIEDILNIVAQLTSRVFLGERLCRDKEWLQITKEYARNSFMGSEELRQCLPLTRPLMQFFMPACTQLRKFSAAARRLIDPEVQARKRRAEEAIKLGKKPPKVEDTIGWMVEVARGRQVDYVGGQLALSIAAIHSSTDNLSKAVVKLCEMPEIVAPLREEITTVLESTDGWSKPALYRMKLLDSFLKEVQRLAPFTIVGMHRRVMKGYVLSDGTHLPKNSRIMVMNDKLRDSSVYEDPDTFKYDRFARLREQPGQEDQHQLASTSSEFATFGHGEHACPGRFFAANQLKIIMACLLLKYDFCFQPGQAEKARVIPFEMVETIDPTLKIEVRRRSEELDVTKVAKETA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C (PubMed:19097780).  In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) that is further converted into fusicocca-2,10(14)-diene, the first precursor for brassicicene C (PubMed:19097780).  Fusicocca-2,10(14)-diene is then substrate of cytochrome P450 monooxygenase bsc1 for hydroxylation at the C-8 position (PubMed:19700326).  Oxidation at C-16 position to aldehyde is then catalyzed by the cytochrome P450 monooyxygenase bsc7, yielding fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:19700326).  Follows the isomerization of the double bond and reduction of aldehyde to alcohol catalyzed by the short-chain dehydrogenase/reductase bsc3 to yield the diol compound fusicocca-1,10(14)-diene-8 beta,16-diol (Probable).  The next step is the oxidation at the C-3 position of fusicocca-2,10(14)-diene-8-beta,16-diol catalyzed by the alpha-ketoglutarate dependent dioxygenase bsc9, to produce a triol compound (PubMed:21299202).  Methylation of the hydroxy group at position 16 is performed by the methyltransferase bsc6 (PubMed:19097780).  16-O-methylation is followed by oxidation at the C-13 position to ketone and an alkyl shift of the methyl group leads to brassicicene C (Probable).  Although the probable acetyltransferase bsc4 is included in the gene cluster, no acetylation reactions are necessary for brassicicene C biosynthesis.  However, the fact that brassicicene E, which is a structurally related compound having an acetoxy group at position 12, was previously isolated from another strain of A. brassicicola suggests that the ATCC 96836 strain might also produce a small amount of brassicicene E (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase bsc2, Brassicicene C biosynthetic gene cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL32_PSYA2
Sequence: MAVQKSRKSRSRRDMRRSHHRMEIAEISIDATTGEKHRRHHMTKDGFYRGRQLFKVSQDA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SYFB_METS5
Sequence: MPTINLNKWILQDMTGLNEQELVDYLFKLKSEVSPVSQDEYSIEVNADRLDMLSLGGIVRALKGITGKELGEPSYPVKDTDYVLEVEKVASRPYALACVIYNVKLSPDFYLKELIQFQEKLHDTIGRRRKKVAIGIHDLEKVEGKIIRYAPVSLSTTFIPLNQEREMSVRDVLQETPQGKQYGNISVWDSNSPAIMDERGILSVPPVINSDRTKITGNTKSLLIDVTGTNFESVMETMDLLATALAELGGIIGRVKVRGMSVDRSPVLRHTSVPFSLDDVNKRLGIHVSRDEAINLIRMMRMEVETNKDLAVIVPPYRVDIMNYTDVAEDIAMAYGYDRFTLESGRTASRGSLSEKSEIYRKLRTLLVGAGFQEVYTLVLTKSSYQRGEAVNIANPISVEYDSVRNSLLWNSLVFLSNNQHSRFPVRIFEIGDVVNRDDSKDTKYSNSTRLSMAIMDSRVSYEMLQAPLHEVLLNLLGVAPSYRRFESDIFMKGRSAEVVVKGETIGRLGEANPELLRSFGLLYPVLLAELDLDALRRVM
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_ANTSP
Sequence: MTATLERRESASLWARFCTWITMNENRLYIGWFGVVMIPTLLTATSVFIIACFAAPPVDIDGIREPVAGSLLYGNNIISGAIIPSSAAIGIHFYPIWEAASLDEWLYNGGPYQLIVLHFLLGVCCYIGREWEFSYRLGMRPWISVAFTAPVVAASAVFLVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPLHQLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANNGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGLWPVVGIWFTSMSVSTMAFNLNGFNFNQSVVDSQGRVINTWADILNRANLGMEVMHERNAHNFPLDLASNESLPLALVAPAING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RAB10_CANLF
Sequence: MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKVNINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane (By similarity).  Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane (By similarity).  In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response (By similarity).  Also plays a specific role in asymmetric protein transport to the plasma membrane (PubMed:17132146).  In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane (By similarity).  In epithelial cells, it regulates transport from the Golgi to the basolateral membrane (PubMed:17132146).  May play a role in the basolateral recycling pathway (PubMed:17132146).  May also play a role in phagosome maturation (PubMed:20028485).  May play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion (By similarity).  Together with LRRK2, RAB8A, and RILPL1, it regulates ciliogenesis (By similarity).  When phosphorylated by LRRK2 on Thr-73, it binds RILPL1 and inhibits ciliogenesis (By similarity).
What are the official names of this protein?
Ras-related protein Rab-10.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Recycling endosome membrane. Cytoplasmic vesicle, phagosome membrane. Cell projection, cilium. Endoplasmic reticulum membrane. Note=Associates with SLC2A4/GLUT4 storage vesicles (By similarity). Localizes to the base of the cilium (PubMed:20576682). Transiently associates with phagosomes (PubMed:20028485).
Protein: PROA_NEIMB
Sequence: MSNTQKQLALAKAAKKSVNTADTEEKNRALLAMADSLEAATADILAANRQDLEAAAGNIPESMTDRLLLDGKRICAMADGIRAVAALPNPVGEILETSTLPNGLEIVKKRVAMGVIGIIYESRPNVTSDAAALALKSGSAVVLRSGKDAFQSARAIVAALKTGLAQTRIDPDALQLIEDTGRESSYEMMRAKDYLDLLIPRGGAGLIRAVVENAVVPVIETGTGIVHIYIDKDADWDKALRIVYNAKTSRPSVCNSMEVLLVHEDIAADFLPKLERLLVRDRIEAGLPPIRFRLDPQAARHIGGEAAGADDFDTEFLDYILAVKTVASVEEAVWHIETHSTHHSDGIVTENRHAADYFTTHIDSAAVYVNASTRFTDGGEFGLGCEMGISTQKLHARGPMGLKELTSYKYIVQGTGQVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_SALPB
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: XLOA_VIBSX
Sequence: MTTTIQNPILKGFNPDPSIVRVGDDYYIATSTFEWFPGIQLHHSRDLINWRLVGHALTRTSQLNMMGMDNSEGVYAPALTYSDGTFWLCFSNVHSCRGGNWMATPSYVVTADSIEGPWSEPVPIGNYGFDPSLFHDDDGKKYMLNMIWGGRAKTNFFGGIIMQEFDADEGKLVGAPKTVFEGTELGCTEGPQLLKKDDYYYLITAEGGTERNHAVTVCRSKHIWGPYEVHPENPILTSRFQEHAELSRAGHGFLVETQTGEWYMSHLCGRRIPNPEGYQFMPKYDNGFSILGRESALQKAHWQDDWPYIATGKTPVVEVEAPNLPLHPWPESPARDEFIDPTLSLISTLREPVSEKWLSLSERPGFLRLKGRHYLYSRYEQSMVARRFQAHNATVETKLEFKPNTPYEMAGLCAYYARNGHYFLKMTANDLGERVLQVVGNINDVYGEYSNDVVIGDADTVYMRLELKTQWYQYSYSLDGVDWYEIGPALNSTPLSDEGGPDIFRFTGSFAALFVADITGQKRHADFDYFEYLEH
What is the function of this protein?
Beta-1,3-xylosidase that hydrolyzes beta-1,3-xylooligosaccharides to D-xylose.
What are the official names of this protein?
Xylan 1,3-beta-xylosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
Protein: ARAD_SACS2
Sequence: MIKDIRTYKLCYEGINDERDALAIKGLAEHPMEIVATEIETSDGYVGYGESLAYGCSDAVQVTIEKILKPLLLKEDEELIEYLWDKMYKATLRFGRRGIAIAGISGVDTALWDIMGKKAKKPIYKLLGGSKRKVRAYITGGYYSEKKDLEKLRDEEAYYVKMGFKGIKVKIGAKSMEEDIERLKAIREVVGEDVKIAVDANNVYTFEEALEMGRRLEKLGIWFFEEPIQTDYLDLSARLAEELEVPIAGYETAYTRWEFYEIMRKRAVDIVQTDVMWTGGISEMMKIGNMAKVMGYPLIPHYSAGGISLIGNLHVAAALNSPWIEMHLRKNDLRDKIFKESIEIDNGHLVVPDRPGLGYTIRDGVFEEYKCKS
What is the function of this protein?
Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy-D-arabinonate.  Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate.
What are the official names of this protein?
Arabinonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: DNAK_DESAP
Sequence: MSKIIGIDLGTTNSCMAVMEGGEAVVMPNAEGGRTTPSVVGFSKTGERLVGQVAKRQAISNPERTVTSIKRYMGTDHKVRIEGNEYTPQEISAMILQKMKTDAEAYLGSKVERAVITVPAYFSDAQRQATKDAGRIAGLKVERIINEPTAAALAYGLDKEEDQTILVFDLGGGTFDVSILELGDGVFEVKATSGNNRLGGDDFDQRIIDWIVAEFKKESGIDLSRDRMAMQRLREAAEKAKVELSSVVNTNINLPFITADAEGPKHLDLNLSRAKFEELTADLIEMTMGPTRQAMQDAGLEPKQIDKILLVGGATRMPSVQEAVRRFFGKEPHKGINPDECVAIGAAIQAGVLTGEVKDVVLLDVTPLSLGIETLGGVFTKIIERNTTIPTARSQIFTTAADNQPSVEIHVLQGERQMAAGNKTLGRFNLVGIPPAPRGIPQIEVTFDIDVNGIVNVSAKDLGTGKSQSITITGSTGLSDAEIERMVKEAEQYAEEDRKRREEVEIRNNADALVYQSEKTLKEHRDQADPNQVSELEQAVDRLKKALEGGDIERIKRETENLTGPLHAFTAAMYQKQAQQQQPGPGPDAGKDKDDKDKTVDADYEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NTF2_DEBHA
Sequence: MSVDFNTVASEFCNFYYQQFDSDRTQLGNLYREQSMLTFETSQLQGAKDIVEKLVSLPFQKVAHRISTLDAQPGSPNGDILVMVTGELIIDDEQNAQRYSQVFHLIPDGNSYYVFNDIFRLNYS
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_STRCO
Sequence: MAVRAAVAGASGYAGGELLRLLLTHPEVEIGALTGNSNAGQRLGALQPHLLPLADRVLEATTPEVLGGHDVVFLALPHGQSAAVAEQLGPDVLVVDMGADFRLKDAGDWERFYGSPHAGTWPYGLPELPGARAALEGSKRIAVPGCYPTAVSLALFPAYAASLAEPEAVIVAASGTSGAGKAAKPHLLGSEVMGSMSPYGVGGGHRHTPEMIQNLGAVAGEPVTVSFTPTLAPMPRGILATCTAKAKPGVTAESVRAAYEKALADEPFVHLLPEGQWPATASVYGSNAVQVQVAHDAAAGRIIAISAIDNLAKGTAGGAVQSMNLALGLDETTGLTTIGVAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICLN_ARATH
Sequence: MVAGLRDFTLRTEDGSGKPVLDESNGEELMHVQTSVAVALGNRPIESPGTLYITSRKLIWLSDVDMAKGYAVDFLSISLHAVSRDPEAYSSPCIYTQIEVEEDEDDESDSESTEVLDLSKIREMRLVPSDSTQLETLFDVFCECAELNPEPVQEEEEESGHNWVFSADQMDVRGGDDDAEWQISQSPTSVIGHSNGDEGLNQPMLELQINDQRFEDAEEMVHESETKDH
What is the function of this protein?
May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
What are the official names of this protein?
Chloride conductance regulatory protein ICln, I(Cln), Chloride ion current inducer protein, ClCI.
What is the protein family that this protein belongs to?
Belongs to the pICln (TC 1.A.47) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IDER_MYCTU
Sequence: MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMERDGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDANLVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETTPGGGVTIVIPGHENVTLPHEMAHAVKVEKV
What is the function of this protein?
Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism.  Acts as a repressor of siderophore biosynthesis and as a positive modulator of iron storage.  Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators.
What are the official names of this protein?
Iron-dependent repressor IdeR.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO10_HALSA
Sequence: MMVPVRCFSCGTVVGEHWEAFKARAETHDGDEDPADVLDDLGVDRHCCRRMLIAHQDLVDVVSPYQ
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_RHOPT
Sequence: MTASLKAIDGSAELTTLMTDLGRQARAAARILALAPPEQKNRALEAMERAIRAGADKILAANAEDVDDAKAAGTTSAFLDRLTLTPARVEAMAEGIAVVRGIADPVGTVTESWQRPNGMTIERVRVPLGVVAVIFESRPNVAADAGVLCLKSGNAVILRGGSESFRSCRAIHDCLVQGLREAGLPDAAITLVPTRDRAAVGLLLAGLDGSVDVIVPRGGKSLVARVESEARVPVFAHLEGVNHVYVDRSADLEMAKSIVLNAKMRRTGVCGAAETLLIDRAAATTHLAPLVTMLIDSGCEVRGDQTVQKVDPRVKPASDEDWDTEYLDAVIAAKLVDGVDGAIAHIHNHGSHHTDAIVAEDVQAAAKFLGEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGAEQLTTFKYRIHGSGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.