PharMolix/UniProtQA huggingface dataset:
Protein: UB2D4_HUMAN
Sequence: MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPEIAHTYKADREKYNRLAREWTQKYAM
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D4, E2 ubiquitin-conjugating enzyme D4, HBUCE1, Ubiquitin carrier protein D4, Ubiquitin-protein ligase D4.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL30_BACAH
Sequence: MAKKLEITLTRSVIGRPQDQRATVEALGLKKLNSTVVKEETPAILGMINKVSHLVTVKEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: XYLT1_CANLF
Sequence: MVAAPSARRLVRRSHSALLAALTVLLLQTLVGWNFSSLHSGAGERRGGAAAGCTEQPAPPPAPAPRRERRDLPPGPAAPLGACCGGGGRGPPARARARALAGCPEEPRPQQPAGQGALPTRALDGYFSHRPKEKVRTDSNNENSVPKDFENVDNSNFAPRTQKQKHQPELAKKPPSRQKELLKRRLEQEEKGKGQSFPGKGTHEALPPGGRAAVNGSHGKDAPRQPHTRKSGGGSPELRYDQPPKCDISGKEAISALSRAKSKHCRQEIGDTYCRHKLGMLMPKKVTRFCSLEGKANKNVQWDEDSVEYMLANPVRIAFVLVVHGRASRQLQRMFKAIYHKDHFYYIHVDKRSNYLHRQVLQFARQYGNVRVTPWRMATIWGGASLLSTYLQSMRDLLEMTDWPWDFFINLSAADYPIRTNDQLVAFLSRYRDMNFLKSHGRDNARFIRKQGLDRLFLECDAHMWRLGDRRIPEGIAVDGGSDWFLLNRKFVEYVTFSTDDLVTKMKQFYSYTLLPAESFFHTVLENSPHCDTMVDNNLRITNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFHRFQQTARPTFFARKFEAVVNQEIIGQLDYYLYGNYPAGTPGLRSYWENVYDEPDGIHSLSDVALTLYHSFARLGLRRAESSLHVETGNSCRYYPMGHPASVHLYFLADRFQGFLIKHHATNLAVSKLETLETWVMPKKVFKIASPPSDFGRLQFSEVRVGTDWDAKERLFRNFGGLLGPMDEPVGMQKWGKGPNVTVTVIWVDPVNIIAATYDILIESTAEFTHYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQPIKPEEVLKLHNGPLRSAYMEQSFQSLNPVLSLPISPAQVEQARRNAGSTGATLEHWLDSLVGGTWTAMDICATGPTACPVMQTCTHTAWSSFSPDPKSELGAVKPDGRLR
What is the function of this protein?
Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN.  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.  Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones.
What are the official names of this protein?
Xylosyltransferase 1, Peptide O-xylosyltransferase 1, Xylosyltransferase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ENGB_ROSDO
Sequence: MQLPFPVAQDPDQHSLEKGRLLFAGDTEFVKGVVAMSGLPDPDRLEVCFAGRSNVGKSSLINALTGRKGLARASNTPGRTQEINFFTAGESHYLVDLPGYGYANAPVPVVEKWQRLLKQYLSGRQTLRRAFVLIDARHGVKKVDEEILSLLDSAAVTFQVVLTKADKVKEKEREKVLDQVRTALSKHPAAFPELVITSSEKGWGIPTLRSIITDLT
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RSLA_MYCTU
Sequence: MTMPLRGLGPPDDTGVREVSTGDDHHYAMWDAAYVLGALSAADRREFEAHLAGCPECRGAVTELCGVPALLSQLDRDEVAAISESAPTVVASGLSPELLPSLLAAVHRRRRRTRLITWVASSAAAAVLAIGVLVGVQGHSAAPQRAAVSALPMAQVGTQLLASTVSISGEPWGTFINLRCVCLAPPYASHDTLAMVVVGRDGSQTRLATWLAEPGHTATPAGSISTPVDQIAAVQVVAADTGQVLLQRSL
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigL.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.
What are the official names of this protein?
Anti-sigma-L factor RslA, Regulator of SigL, Sigma-L anti-sigma factor RslA.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DNLJ_CHLSY
Sequence: MSHTTVADRINELRSLIRRYDYHYYVLDDPIVSDAEYDALMTELRALEAAHPELITPDSPTQRVSGTPASQFAKVQHPQPMLSLGNAFTKADLLAWRDRVLRLLGPDAIVAYVVEPKIDGLAVALTYRDGRLVQGATRGDGEVGEDVTANLRTIGSIPLTLQATSTPQDDDLPTTLPTTIEVRGEVYMRTADFETLNDRLAAAGEKIFANPRNAAAGSLRQKDPTITAARPLRFFAYGVGVVEGISLSSQWQTLRYLRALGFPVNQDVRRFTDFAEVLAYCEAWMAKRDDLPYEADGVVIKIDDFAQQRELGVVGRDPRWAIAFKFPAREAITRLLDITVNVGRTGVVTPNAELEPVQIGGVTVRNASLHNADYIAQRDIRIGDYVIVKRAGDVIPYVVGPVIARRDGSERPWQFPTHCPACGSPLEREEGEAAWRCNNFSICPAQLVRRVEHFVSRSALDIVGMGERQAELFVQRGLIRDVADIFFLKADQLAELEGFGPKRIANLLAAIDAARQRPLDRLLVGLGIRYVGTVAAQTLVAALGSLDAIMAARQEELEQIPGIGPVVAASIVDFFSRPANRALIEKLRAAGVQMGGVSGPTRQSDTLAGKTFVLTGTLPSLSREQASALIVAHGGKVTDSVSKKTSYVVAGANAGSKLAKALQLGIPVIDEAGLLALIGTTAEPPPSPPPPPPETNTDGNQLLLPLDGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: A1AT_CHILA
Sequence: EDAQVTDLPDHEQEHLAXHKIAPXLAEFAY
What are the official names of this protein?
Alpha-1-antiproteinase, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_ACHLI
Sequence: MSEEKSVLRDLNLKNDDELMLRPQTLNQYIGQDDIKEMLSIYIQAALKREESLDHVLLYGAPGLGKTTLAQIIANELGVDIKITSGPAIEKTGDLVALLSSLSPGDVLFIDEIHRIPRFVEEVLYSAMEDYTLDIVLDKERDSRSIRIELPPFTLIGATTRFGDLSHPLRERFGAVFRLSYYKLEEIKQIVRRTSKVYQNEIDEKAVDELSKRSRGTPRIANRLFRRVRDFAEIMTDAVITLDITQLALTKLGIDHKGLDASDYLYLRGIVERFNGGPVGLESLASTIGEEPGTIEDVYEPYLLQEGYIKRTPRGRVATELAYNLLGVKYYKGLLDN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GCSH1_SACS2
Sequence: MNEMKVGRYVVLTDRLYTETDEWVVLSNDNVAVIGITDYAQKKLRDIVGIELPQLQKEVKAGESVGVIESVKAAADIFSPLSGIIVEVNNKLLEHPEIINKDPYGEGWIFKLKASKLSEEKEKLLSPEKYIEKIKGG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein 1.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y05M_BPT4
Sequence: MKIEALNQEGNIYVIINGDFFVDMDEVTSEELVELLKKRYNMCDEVATHMACAIFSLSYVVE
What are the official names of this protein?
Uncharacterized 7.1 kDa protein in mobD-ri intergenic region.
Protein: VIAA_PECCP
Sequence: MITLESLEMLLSIDENELLDDLVVTLLATPQLAFFFEKYPSLKSALLNDLPHWKETLKQRLRTTQVPPDLEKEFSCYQRSQSIDNQAFQTRLPAIMDTLSNVESPFLTQASQLITAPERTLGQKVTSGLHALFLQRWRLSLTLQTVSLHQQLMEQEREILLDELQQRLTLSGKLEPILAENENAAGRLWDLSAAQRIQTDPRPLLDFGAFLQRQPALQKLAERLGRSRETKSILTQEAPKEAFRVSVREPATVPEQVSGVHQSDDILRLMPTELVTLGISELEYEFYRRLLEHRLLTYRLQGESWREKITERPVVHQQNEQQPRGPFIVCVDTSGSMGGFNERCAKAFCLALMRIALADNRRCYIMLFSTGVVKYELTSADGLEQAIRFLSQSFRGGTDMSACLSALLDKMDDALWHDADAVVISDFIAQRLPDEVVNKVKSRQTQLQHRFHAVAMSDHGKPGIMHIFDHIWRFDTGLKSRLMRRWQHGKAY
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: SELO_EXISA
Sequence: MTTDWNFEATYLELRDIFYDRGPIHPVDNPTLVLFNDALAASLGLDAQSLKQDIDLLAGNRQTETSFSQAYAGHQFGNLTMLGDGRALMLGEHVTPNGKRVDVQLKGSGPTEYSRGGDGRAALGPMVREFIISEAMHALGIPTNRALAVIQTGEAIMRQGPKHGAILTRVASSHLRVGTFQFAAGAGSIDDVIALTEVAIKRHDPDLIDAPNRYEQFLGRVVERQARLIANWQLVGFIHGVMNTDNMFISGEGLDYGPCAFMDTYHPETVFSSIDREGRYAYANQPYIGSWNLARLAETLLPLLGETKEEAVDVANKQLTRYTELYKEAYFTGLAHKIGLFVRKDGDDELTDELLRLMMETEADYTNTFRSLTLGEIESLPFATRKDGKVWLGAWRKRLNGQGLPDEDVSRIMRQYNPAVIPRNHHVEKAIQAAERGDFGPTEAILTILRDPYNYDQSSEYVSAGPPRTYPYQTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL36_STRM5
Sequence: MKVLSSLKSAKARHRDCKVVRRRGKIFVICKSNPRFKARQR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CD14_RABIT
Sequence: MEPVPCLLLLLLPLLRASTDTPEPCELDDDDIRCVCNFSDPQPDWSSALQCMPAVQVEMWGGGHSLEQFLRQADLYTDQRRYADVVKALRVRRLTVGAVQVPAPLLLGVLRVLGYSRLKELALEDIEVTGTAPPPPPLEATGPALSTLSLRNVSWPKGGAWLSELQQWLKPGLQVLNIAQAHTLAFSCEQVRTFSALTTLDLSENPGLGERGLVAALCPHKFPALQDLALRNAGMKTLQGVCAALAEAGVQPHHLDLSHNSLRADTQRCIWPSALNSLNLSFTGLQQVPKGLPAKLNVLDLSCNKLNRAPQPGELPKVVNLSLDGNPFLVPGASKLQEDLTNSGVFPACPPSPLAMGMSGTLALLQGARGFI
What is the function of this protein?
Coreceptor for bacterial lipopolysaccharide.  In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:1375269).  Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (By similarity).  Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).
What are the official names of this protein?
Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note=Soluble, secreted forms seem to exist. They may arise by cleavage of the GPI anchor.
Protein: Y3095_MYCTU
Sequence: MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSSDPERHEYRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Rv3095.
Protein: RL32_CHESB
Sequence: MAVPKRKTSPSKRGMRRSADALKAPTYVEDKNSGELRRPHHVDLKTGMYRGRQVLEPKEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CH60_AERHH
Sequence: MAAKEVKFGNEARSKMLEGVNILADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFMNMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVVAAVAELQALSQPCADNNAIAQVGTISANSDEKVGKLIAEAMDKVGRDGVITVEDGQGLDDELAVVEGMQFDRGYLSPYFVNKPETGAVELDDPFILLVDKKVSNIREMLPVLEGVAKAGKPLIIVAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGMELEKATLEDLGRAKRIVITKENTTIIDGVGDASLIESRVAQIRQQIEETSSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALVRVAAKLAGLRGDNEDQNVGIKVALRAMEAPLRQIVINAGEEASVIANAVKNGEGNFGYNAYTEQYGDMLAMGILDPTKVTRSALQFASSIAGLMITTECMISELPKKDAPAMPDMGGMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_DINSH
Sequence: MKFFVDTADVAAIAELNDLGMVDGVTTNPSLILKSGRDITEVTKEICELVDGPVSAEVVATQADAMIAEGRKLAEIAENITVKLPLTWDGLKACKTLTDEGKMVNVTLCFSANQALLAAKAGASFISPFIGRLDDLNVDGMELIEDIRTIYDNYGYETEILAASIRTVNHMKEAALIGADVATAPPGVIKQMANHVLTDKGLAAFLSDWEKTGQKIL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STRS2
Sequence: MSVSFEAKETNRGVLTFTIGQDAIKPELDRVFNKVKKDINLPGFRKGHLPRAVFNQKFGEEALYQDVVNALLPAAYEAAVAEAGLEVVAQPKIDVVSMEKGQDWTITAEVVTKPEVKLGDYKNLAVSVEATKEVTDEEVDAKIEAARNNLAELVIKEGPATEGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEAQLVGHAAGEEVNVEVTFPEDYQAADLAGKQALFVTKIHEVKAKEVPALDDELAKDIDEEVETLDELKAKYRKELEASKEVAFDDAVESAALELAVENAEIVELPEEMIHEEVHRAINEFLGGMQQQGISPDMYFQITGTTREDLHKQYEADAEKRTKTNLVVEAVAKAEGFEATEEEINKEIEDLAATYNMEVAQVRSLLSPEMLKHDIAVKKAVEVITSTATVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ML26B_DANRE
Sequence: MLLSPAAERSQGSLLSVIMEILKDQSHRELFGLELGSGTGQHVVHFAQEMPFVTWLPSDTKEESRNSIRAYIEATKAKTVLEPVHLDASEPWDKWAGLPQNSCDIILAINLLQYTPFSTAEGVFKGSGQILKQNGLLMTYGPYAINGTITPICNEQLDETLRQMNPEWGLPDIDVLRQLAFSNGMRMERMIEMPESNKCLVFRKL
What are the official names of this protein?
Methyltransferase-like 26 B.
What is the protein family that this protein belongs to?
Belongs to the UPF0585 family.
Protein: XNI_SALTY
Sequence: MAAHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIIHSQPTHAVAVFDDDARSSGWRHQRLPDYKAGRPPMPDDLHNEMPALRAAFEQRGVRCWASDGNEADDLAATLALKVTEAGHQATIVSTDKGYCQLLSPGLRIRDYFQKRWLDAPFIEKEFGVLPRQLPDYWGLAGISSSKVPGVAGIGPKSATQLLIQFQNLEGIYAHLDEVPEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLAR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: MT3_YARLI
Sequence: MEFTTAMLGASLISTTSTQSKHNLVNNCCCSSSTSESSMPASCACTKCGCKTCKC
What are the official names of this protein?
Metallothionein-3, MT-3, MTPIII, Metallothionein-III, MT-III.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 11 family.
Protein: MNMG_ACET2
Sequence: MEFLAGEYDVAVVGAGHAGCEAALAAARLGVKTVVFAINLDSIANMPCNPNIGGTAKGHLVREIDALGGEMGKNADKTFIQSKILNSAKGPAVYSLRAQVDRRSYQIEMKNTLEKQENLDVKQAEIVEILYDEVEGKKTVRGVKTHTGAIYKSKVVILATGTYLKGKIIIGDVSYSGGPDGLFPANKLSDSLREMGIELMRFKTGTPARVNRRSIDFSKMEEQPGDERIVPFSFENEEIKKEQVSCYLTYTNSETHRIIRENLHRSGLFGGLIEGIGPRYCPSIEDKVVRFSDKESHQVFVEPMGLNTQEMYLQGMSTSLPEDVQIEMLRTIPGLENVSIMRNAYAIEYDCINPTQLKLSLELRDVEGLFTAGQINGTSGYEEAAAQGIIAGINAARKIKGLEPLILDRSQAYIGVLIDDIVTKGTNEPYRMMTSRAEYRLLLRQDNADLRLTPIGYEVGLISEERYRKFEEKRRLIEQEIERVKKTNIAPTEKVNEFLKKHNSTPIKSGVKLADLLRRPELDYDTLAEIDENRPDLSFAVREQVSISIKYEGYIKRQMQQVEQFKKLEERKLDKDINYDEIKGLRLEARQKLNKIKPESVGQASRISGVSPADISVLLVYLEQRKRQKS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJFY_ECO57
Sequence: MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYINHNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR
What are the official names of this protein?
Uncharacterized protein YjfY.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRPA_ALKMQ
Sequence: MISRITNKLQALKEYDEKALITYVTAGDPDLETTFDLVLAMEKAGADIIELGIPYSDPLADGPVIQRASQRALNAGANMEAIFELVIKLREKTQIPLVFLVYYNCVFKYGLETFLNRCQEIGIDGLIIPDLPLEERRELQVMMQQYPMDLIPLVAPTSEDRMKEIVQDAEGFIYCVSSTGVTGKRNSLAGNLEGFMQQLRTYTEIPLVIGFGISNSEMMDKLKNICDGFIIGSAVIEKIEAGLEDRSSVERVSKFIEKLYEFKNLG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TRA0_MYCSM
Sequence: MSEVLPLLYLHGLSSNDFTPALEQFLGSGAGLSASTITRLTAQWQDEARAFGARDLSATDYVYLWVDGIHLKVRLDQEKLCLLVMLGVRADGRKELVAITDGYRESAESWADLLRDCKRRGMTAPVLAIGDGALGFWKAVREVFPATKEQRCWFHKQANVLAALPKSAHPSALAAIKEIYNAEDIDKAQIAVKAFEADFGAKYPKAVAKITDDLDVLLEFYKYPAEHWIHLRTTNPIESTFATVRLRTKVTKGPGSRAAGLAMAYKLIDAAAARWRAVNAPHLVALVRAGAVFHKGRLLERPTDITPPTSPSDGGQHAGTEVA
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Transposase for insertion sequence element IS6120.
What is the protein family that this protein belongs to?
Belongs to the transposase mutator family.
Protein: GLYA_SALA4
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIVPYGIDESGKIDYDEMAKLAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGDEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDNINDEATIERVKAKVLDICARFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ALIF1
Sequence: MAKKVEAYIKLQVAAGMANPSPPVGPALGQHGVNIMEFCKAFNAKTESIEKGLPIPVVISVYNDRSFTFVTKTPPAAVLLKKAAGVKSGSGRPNTEKVGTVTDAQLQEIAETKAADMTGADIEAMKRSIAGTARSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: APAH_RALSO
Sequence: MTVASIPPHAIGDLQGCCSPLQTLLTALPANAPLRFVGDLVNRGPDSLGTLRRVIMLCEGGRARAVLGNHDIHLLAVAAGVRKLGKRDTLDDILGAPDCDALIHWLRHQPLAIFENGFLMVHAGVLPQWTTGDVLELAGAVERELRSPHWKTFLTDAFGNQPAKWSSDLIGIDRLRLTINALTRLRFCTPDGAMEFETTDADGAPDGHVPWFDVPGRRTRGTPIAFGHWSTRGLVMRDDLLGLDTGCVWGGKLTAARMTLAPAGREVIQVACEQAQDPLAHKK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: G6PI_FRATW
Sequence: MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGVLIALYEHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_NOVAD
Sequence: MSDTADRVKKIVVEHLGVEADKVTEEASFIDDLGADSLDIVELVMAFEEEFGVEIPDDAAEKISTVSDAIKYIDENKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_SALTY
Sequence: MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHRENITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALREKVAEA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.