PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_PSEFS
Sequence: MSAQDFLVELGTEELPPKALNTLADAFLAGIEKGLHSAGLKFEAKKVYAAPRRLAVLLTALETQQPDRSINLDGPPRQAAFDAEGNPTQAALGFAKKCGVELSEIDQSGPKLRFSQVITGKPTASLLPTIVEDSLNDLPIPKRMRWGARKEEFVRPTQWLVMLLGDQVIDCTLLAQKAGRDSRGHRFHHPQAVRITSPANYAADLRAAYVLADANERRELISKRTEELARLQEGTAIVPPSLLDEVTALVEWPVPLVCSFEERFLDVPQEALITTMQDNQKYFCLLDVDGKLLPRFITVANIESKDPQQIIAGNEKVVRPRLTDAEFFFKQDKKQKLEDFNLRLQNVVFQEKLGSVYDKAVRVSKLAAYIAQRIGGDAAWAARAGLLSKCDLATEMVGEFPEMQGVAGYYYALNDGEPDDVALALNEQYMPRGAGAELPTTLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIDKKLDLDLTQAVVFAVGQFGAKVKQAGLAEQVLEFVFDRLRARYEDEGVDVSVYLSVRALQPGSALDFDQRVQAVQAFRKLPEADALASVNKRVSNLLSKAEGLGNADVDPGLFADAKEFSLNSAIAKAENAVKPLIAERNYAEALARLATLREPVDAFFEAVMINAEDAGVRKNRYAMLARLRGLFVNIADISTLS
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_HELHP
Sequence: MTIIAGNFKANLTRIQVATFAKELDSILTDMQTSSHLQVDIFPSHTALLTNNFKHFHIGAQNAYFAQNGGFTGEIGLSQLQEFNINRLIIGHSERRTLFGENQDFINKKFRFYAEAGFEIYYCIGEPLSMRQKGKNALKDFLGAQLDGIDITYPKLIIAYEPIWAIGTGESATLEQIESTHSMLATFTSAPLLYGGSVNPTNAREILCTPYVNGVLVGSASLNIQSFTDIIRASK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPA_DROME
Sequence: MSKPITFVTGNAKKLEELVAILGPSFPRTIVSKKIDLPELQGDIDEIAIKKCKEAARQVNGPVLVEDTSLCFNALEGLPGPYIKWFLEKLQPEGLHRLLHGWENKSAQAICTFGYCDGVDAEPLIFKGITEGVIVEPRGPRDFGWDPVFQPSGYDKTYAELPKSEKNTISHRYRALALLRQHFEKQDKLIN
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_ROSS1
Sequence: MNAPRLTDTTLRDGSHALAHTFTRQQVRDIVRALDRAGVPVIEVTHGDGLAGSSLQYGFSRVPDLDLIAEARETAERARIAALLLPGIGTRRELRAAVERGVQVLRIATQCTEADISEEHFKMAKDMGLETVGFLMMSHMRPPEFLAEQARLMESYGADCVYVVDSAGAMLPHDAAARVQALKAALTVQVGFHAHNNLGLGIGNTLAALEAGADQIDGCLRGLGAGAGNAATEVLAAVLDRLGINPGLDVLALMDAAEYVVAPIMPFQPFPDRDAITIGYAGVYSTFLLHARRIGEQLGVDPRAILIELGRRQTVAGQEDWILDVALELVRQQQTTPV
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PRMA_SALNS
Sequence: MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGILASQAESICDAYAELFTLDPVVEKEEWCRITGRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_PAPAN
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: PET18_YEAST
Sequence: MSCTTDKLIQKYDALVRKTTEHKFAKELCAGTLKDRSLYIYLSQDLQFFETSLRLICKTTSLAPTTHALITLAKKIGFFSNDENSYFHDCLELLAPSLTKEERDNFDNKAIPGVDAYINFLDELRKDASITWPSLVTSLWVAEELYWRWARDTPRAPGLHWKYQKWIDLHDGEHFQTWCEFLKAEVDKFPVEEVESIFVKVSQFEFEFFESCYNA
What are the official names of this protein?
Protein PET18.
What is the protein family that this protein belongs to?
Belongs to the thiaminase-2 family.
Protein: LPXH_SALA4
Sequence: MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREIAAAIKAVVNVGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLVHGHTHRPAVHELSVNDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1550_STAA2
Sequence: MSETLNQIKESFIEYLLFQYRFKSRIAVWVLNYIKVNEAKLANIHFVDTKINHHETLEIAEVGSHASAIQFTKRNIKLMNTNEIFDYIANHNCAFDIQIHFANVSKREQRLDDLIVAQLTESPSYQTYLHDLNSMAIDRHKHALLIDYLLHNIDLSLQMNEKQRFYQLTQILNTLKLVNKHNQFEDLADDD
What are the official names of this protein?
UPF0302 protein SaurJH1_1550.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: RS3A_ORYSJ
Sequence: MAVGKNKRISKGKKGSKKKTVDPFAKKDWYDIKAPSVFNVRNIGKTLVSRTQGTKIASEGLKHRVFEVSLADLQNDEDQAYRKIRLRAEDVQGKNVLTNFWGMSFTTDKLRSLVKKWQTLIEAHVDVKTTDGYMLRLFCIGFTKRRPNQVKRTCYAQASQIRQIRRKMVEIMANQASSCDLKELVSKFIPEVIGKEIEKATSSIFPLQNVFVRKVKILKAPKFDLGKLMEVHGDYAKEDIGTKLDRPAEDEAMAGQEVAAAE
What are the official names of this protein?
40S ribosomal protein S3a, CYC07 protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIS_MACLO
Sequence: CTTGPCCRQCKLKPAGTTCWKTSLTSHYCTGKSCDCPLYPG
What is the function of this protein?
Is a potent and selective inhibitor of alpha-1/beta-1 (ITGA1/ITGB1) integrin.  It blocks the adhesion of alpha-1/beta-1-expressing K562 cells to immobilized collagens IV and I with IC(50) of 2 and 0. 5 nM, respectively.  Potently inhibits angiogenesis in chicken and in mouse model and reduces tumor development by half.  Is 25-fold less potent than viperistatin.
What are the official names of this protein?
Disintegrin obtustatin.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Short disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MSCL_STAAS
Sequence: MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVVEENVVLLTEIRDLLREKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMA_I68A4
Sequence: MKTIIALSYIFCLALGQDLPGNDNSTATLCLGHHAVPNGTLVKTITDDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: MK01_XENLA
Sequence: MAAAGAASNPGGGPEMVRGQAFDVGPRYINLAYIGEGAYGMVCSAHDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFKHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADPKALDLLDKMLTFNPHKRIEVEAALAHPYLEQYYDPSDEPVAEAPFKFEMELDDLPKETLKELIFEETARFQPGY
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Plays an important role in the MAPK/ERK cascade.  Depending on the cellular context, this cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.  The MAPK/ERK cascade also plays a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.  Many of the substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation.  However, other substrates are found in the cytosol as well as in other cellular organelles, and those are responsible for processes such as translation, mitosis and apoptosis.  Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis.  Phosphorylates microtubule-associated protein 2 (MAP2), myelin basic protein (MBP) and Elk-1.  Phosphorylates dual specificity protein phosphatase 1 (DUSP1) during meiosis, increasing its stability.  Activated by M phase promoting factor (MPF).  Plays a role in the spindle assembly checkpoint.
What are the official names of this protein?
Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, M phase MAP kinase, Myelin basic protein kinase, MBP kinase, Myelin xP42 protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Associated with the spindle during prometaphase and metaphase in cultured XTC cells.
Protein: RS14Z_SULDN
Sequence: MAKKSMIVKAAREPKFKVRGYTRCQICGRPHSVIRDFGICRVCFRKMANEGLIPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: Y856_METJA
Sequence: MEMGNGMKDARNLDKQWVVLSELSAELVNRGIKVPEIVFEKLRLANALLSYYILDPHASINILANVERELNYVQSQLFSLCDTELTEKYLDRMIKAIRGEINAKFPVSKSNYNREVKKRGKVEAIRVKLQKEMQIERLSDLGEWHGVIFEYSDEKDKVIIEGNIDRVKRALKDFAFMWKED
What are the official names of this protein?
Uncharacterized protein MJ0856.
Protein: YYBF_BACSU
Sequence: MTYIRKGTPVFRKITFAFFAAGFNTFAILYCVQPLMEEFTREFHVTPTAASLSLSVTTMLLAVSMLVFGSLSEVWGRKPIMGISMLAASVLCLASAFSPSFHTLLVLRTIQGVALAGLPSIAMAYLGEEIEPGSLGSAMGLYISGNAIGAVFGRIVSGLLSEYLNWHMAMGTIGVISLIASVIFFINLPPSRHFTPRKLKLGKLGMSLIGHLRDRKLFSLFLIGFLLLGSNVALFNYIVYVLLGPPYSLNKAFSSWIFIVMIVGIFSSSFIGRMVDRYGYPKILVMNIFIVIAGALFTINNMLAVKILGIALFTFGFFGGHSVASSWVGRRALHNKAQASSLYLFFYYAGSSVFGTIGGLFWSGFHWLGVVGMITFMLLVALWLSGYLARSVKMPDKRNEKGLN
What are the official names of this protein?
Uncharacterized MFS-type transporter YybF.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: POLG_OMV
Sequence: EYTIVRYVDPLTGATQDENPLMAIDLVQEYFAKIRSQLVSEEKLETQNIIANPGIQAYYMKNRGDAALKVDLTPHNPLLVTKTGTIAGFPENEFILRQTGKAVNVKMSEVPVENELEEVEHEGKNLNRGLRDYNVVSNVVCRLTNESDGHSASLFGLGYGGYIITNRHLFKNNNGTLKVQSQHGDFIVKNTTQLKMVPVGKTDILIIRMPKDFPVLPQKLRFRAPANEDKVCLIASNFQERYVSSLVSETSSVYPVGNGEFWQHWISTKDGHCGLPLTSTKDGFIVGIHSLSTITNSKNFFASIPANFEEQYLAKLDQQDWTANWKYNPNEVSWNGLRLQENKPGRIFQAVKEVSALFSDAVYEQGQEVGWLFRELKDNLKAVAVLPNQLVTKHVVKGPCQCFIQYLNESPEASAFFKPLMGQYGKSILSKEAFVKDIMKYSKPIVLGEVDFIKFEEGYNNVLRMFHDIGFEKCEYVTDSMEVYKNLNLKAAVGAMYTGKKQQYFEGMSEDEIHQLVIASCFRLWSGKFGVWNGSLKAELRPLEKVQACKTRTFTAAPLDTLLGAKVCVDDFNAQFYDKHLTAPWTVGICKYYKGWDTFMNKLPEGWLYCDADGSQFDSSLTPFLINSVLRLRLEFMEDWDIGARMLSNLYTEIIYTPIATPDGTVVKKFRGNNSGQPSTVVDNTLMVVLAMNYALAKLSIPYEEMDSRIRYFANGDDLLVAVEPTKGGEILDSLQASFSELGLIYDFNDRTFDKTQLSFMSHQALWDGDMFIPKIKQERVVSILEWDRSTQPEHRIEAVCAAMIEAWGYPELLQEIRKFYAFMVTQEPYSAIHAQGKTRYISERALVTLYKDEKVVLSDIGPYIQKLAEMSLGCVDEVVMHQADSMDAGGSSRPPAPLVRQQDQDVNVGTFSVARVKALSDKMMLPKVRGKTVLNLQHLVQYNPEQTEISNTRATRTQFNNWYDRVRDSYGVTDDQMAVILNGLMVWCIENGTSPNLNGNWTMMDGDEQIEYPLQPVLENAQPTFRQIMAHFSNAAEAYIEKRNSEQRYMPRYGSQRNLNDYSLARYAFDFYEMTSRTANRAREAHIQMKAAALRNTKTKLFGLDGKVGTEEEDTERHVASDVNRNMHSLLGVNM
What is the function of this protein?
Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae genome polyprotein family.
What are the subcellular locations of this protein?
[Viral genome-linked protein]: Host nucleus. Note=Binds to host plant eIF4E proteins in the host nucleus. SUBCELLULAR LOCATION: [Capsid protein]: Virion.
Protein: RL35_RHOBA
Sequence: MGTKIKTHKGTKKRFRLSAKGKAMHRQSGTSHLAKGLSKKRRRNLRGTTAVAECMEPTIHAALNGHSY
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y1903_DEIRA
Sequence: MIAVTTESTADILPLQLGYSGIHLLPVPLGHQGQVYSERELPPDQLVNLIRTTGEPARTLAIDDEVVARTFEAALQGSKSGRLVHVASGSRFTPHFEVAARVAGQFGVRVQVIDGGTVSYALGVQALHAAHLADQGADFGQIARALAELRERTLLTFAVESLDFLRVNGRIGNVAAFIGNWLGLRPLLAVEAGEVVSKARVRGQAAAVRTLLSATHQFQHQTGETLRLYCGHTIGGEGAAEQLQGQLQAVYRDLPAPLHPLGSGLTANVGPGVVAVLAFPRRFGLGHA
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein DR_1903.
Protein: UPP_SHEPC
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALVVDPMLATGGSMIATVDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDIELYTAAIDRCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: LEUD_ACIAC
Sequence: MQKFTLHKGLVAPMDRENVDTDAIIPKQFLKSIKKTGFGPNLFDEWRYLDQPGQPGVPESARKPNPDFVLNQPRYAGASILLARKNFGCGSSREHAPWALDQYGFRAIIAPSFADIFFNNSFKNGLLPIVLPEATVSQLFDEVHAFPGYELTVDLERQVIVRAQGAEIPFEVNAFRKYCLLNGFDDIGLTLRQADKIRAFEAERLATKPWLAHTMPA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: XERC_METS4
Sequence: MLQTTPPDLLPGAADVREAVASWLTLLARERRFSPNTVEAYARDLRQFLAHRARAGTQPDIPSLVALKPRDLRAFMAARRAEGIGGRSLMRALASLRSFARHLEREGHGTVSALSAVRSPKVERRLPRPLPVAAAVALASPDIRAGEDRPDWVLARDAAVLALLYGAGLRIGEALGLRRKDAPVGGLDTLTIVGKGQKTRMVPVIAPVQAALAEYLAACPYALAPDGPLFVGQKGGPLSPRVVQLAVASLRGALGLPDSATPHALRHSFATHLLARQGDLRAIQDLLGHASLATTQIYTKVDSARLMSAFEAAHPRAGRM
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTPC
Sequence: MEFINQTFFSDYSEGKIDTIPYALGIVLALTNGSRILKFINLLISLLRKFIITSKTVIGKFKIENNTSHQNDDIHKEYEEVMKQMREMRVHVTALFDSIHKDNMEWRMSESIRREKKREMKASTAENEVKIHTNDVNICDTSGLETEVCL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: RL30_SHESW
Sequence: MATKTVKVTQTKSGIGRLPKHRATLTGLGLRRIGHTVELEDTPSVRGMINKVYYMVKVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UREG_CERSK
Sequence: MSHGPLRVGIGGPVGAGKTTLTEKLCAALAHRCSMAVITNDIYTREDAEALMRAQVLPAERIRGVETGGCPHTAIREDASINLAAVADLRRTFPDLDLILIESGGDNLAATFSPELADLTIYVIDTAAGQDIPRKRGPGLARSDLLVVNKIDLAPHVGVNLARLEADTQAARGQRPYVMARMRAGVGVEAIVAFLEREGGLLLLPQD
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_STRGC
Sequence: MPTINQLVRKPRKSKVEKSKSPALNVGYNSLKRVPTNESAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVTDRKQGRSKYGTKKPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.