PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_STAAS
Sequence: MEKYILSIDQGTTSSRAILFNQKGEIAGVAQREFKQYFPQSGWVEHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVWQSRQTQSICSELKQQGYEQTFRDKTGLLLDPYFAGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGKAAHITDYSNASRTLMFNIHDLEWDDELLELLTVPKNMLPEVKPSSEVYGKTIDYHFYGQEVPIAGVAGDQQAALFGQACFERGDVKNTYGTGGFMLMNTGDKAVKSESGLLTTIAYGIDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSESYATRVDSTEGVYVVPAFVGLGTPYWDSEARGAIFGLSRGTEKEHFIRATIESLCYQTRDVMEAMSKDSGIDVQSLRVDGGAVKNNFIMQFQADIVNTSVERPEIQETTALGAAFLAGLAVGFWESKDDIAKNWKLEEKFDPKMDEGEREKLYRGWKKAVEATQVFKTE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: DNAI2_RAT
Sequence: MEIVYVYVKKRSEFGKQCNFSDRQAELNIDISPNPELAALYVERNPVDTGIQCSASMSEHEANTERFEMENCGVNHVEGGWPKDVNPQELEQTIRFRKKVEKDENYINAVMQLGSIMEHCIKQNNAIDIYEEYFDDEEAVEVTEEAPSAKTINVFRDPQEIKRTATHLSWHPDGNKKLAVAYSCLQFQRSPMGMSHDSYIWDLENPNRPEIALKPSSPLITLEYNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIEFSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKISEPTEVVIMDITRKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTPAEKIVCTFSGHHGPIYALQRNPFYPKNFLTVGDWAARIWSEESRESSIMWTRYHMAYLSDGAWSPVRPAVFFTTKMDGTLDIWDLVFKQCDPALSLKVCDDPLFCLRVQDTGCLIACGSELGTTTLLEVSSSLSTLQRNERNIASSIFERETRREKILEARHREMRLKEKGKAEGRDDDQKEEETALDLDELVNKAEEEFFEVIFAELKRKEAEALKKKPKPKKASIEVEGEDELEDIAGEEEESGIIMGEDTGEDDMDEKNEGGAP
What is the function of this protein?
Part of the dynein complex of respiratory cilia.
What are the official names of this protein?
Dynein axonemal intermediate chain 2, Axonemal dynein intermediate chain 2.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Dynein axonemal particle. Note=Located in the proximal region of respiratory cilia.
Protein: ILEU_XENLA
Sequence: MENLSSACTHFCFDLFKKINENNSTGNLFFSPISLSTALAMVFLGTKGKTAEQMSKTLHFDAVKDLHSNFQTLNAEINKKDVSTYALNLANRLFGEKTFNFLPNFLSSVKKQYSADLGTVDFISALEDARKEINKWVSEQTKGKIPEVLSTGTVDRSTKLVLVNAIYFKGDWAKKFNAEHTTDMPFQLNKKEQKTVKMMYQKEKLPFNYIPDINCRILELPYVDYELSMIIILPDNINDDTTGLQQLEKELSLEKIHEWTENMMPTDVHIHLPKFKLEDSYKLKSQLAGMGMVDLFNSGSADLSGMSGSNNLFLSEVIHKSFVEVNEEGTEAAAASAGIAMMCMMREEEFNADHPFLFLIRHNATKSILFFGRYSSP
What is the function of this protein?
Regulates the activity of the neutrophil proteases.
What are the official names of this protein?
Leukocyte elastase inhibitor, Serpin B1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_STRM5
Sequence: MKADIHPNYRDVVFHDVTSDFKILTRSTMSTKETIKWEDGNDYPLVKVEISSASHPFYTGKHKVIDTSGRIDKFQKRYAR
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RNH2_DESVH
Sequence: MPPRPQRLAPVADLPPVFAGIDEAGRGCLAGPVVAAAVILPQEYALPGLTDSKKLTAARRESLAEGIRSCAVTWGIGVVWPRDIDRINILQATFRAMARAVRVLRQPPPAILIDGDKTLPPHVLTSLSCDGHLPTQRAIIGGDGCIPAISAASILAKTFRDRLMDTLDRRYHGYGFAKHKGYGTAEHLAAIAAHGPCAQHRLTFRGVRPNPAAEEQLTLW
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_BRASB
Sequence: MNIRSNPDTTLPAVTTGPLPSSRKIYAAPDSAPDLRVPLREIILSEAAGEPNLPVYDTSGPYTDPSVTIDVNAGLPRNRTAWVLERGGVEEYEGRDIKPEDNGNVGADKAAKAFIAHHKPLRGLDGHKITQLEFARAGIITKEMIYVAERENLGRKQQLERAEAALADGESFGAEVPAFITPEFVRSEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCNGDPVKLTWELYKDTLIEQCEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDIMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWTDQFNLGLDPDTAKSFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPTTVGVTISGTIEDGMAQMSAKFKEMGGSVYLDADKVKESNKALS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NHAB_KLEP3
Sequence: MEISYGRALWRNFLGQSPDWYKLALIIFLIVNPLVFAVAPFVAGWLLVVEFIFTLAMALKCYPLLPGGLLAIEALLIGMTSPAHVREEIAGNLEVLLLLIFMVAGIYFMKQLLLFVFTRLLLGIRSKMLLSLAFCLAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASARPDDNDLLDDSHIEQHYREVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGEFFIRMAPVTVPVMVCGLLTCLLVEKYRLFGYGEPLPPTVRKVLQDFDDRSRAQRSRQEQLRLLAQAVIGVWLIVALAFHLAEVGLIGLSVIILATTFSGVTDEHAIGKAFTEALPFTALLTVFFAIVAVIIDQQLFTPVIEFVLQASPHAQLSLFYLFNGLLSSISDNVFVGTVYINEAKTALEHGVISLPQFEMLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLMPVTNWLLAHGWVTTPTLP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_KLEP3
Sequence: MLQPKRTKFRKVHKGRNRGLAQGTDVSFGTFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFGLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PDXT_MYCBO
Sequence: MSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLDLDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQVDSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEMTGDRRIHQLFVDIVTSAA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RPO11_THEGJ
Sequence: MRIEVIKREGNTFEFYLEGEDHTFANLLVETLHEDKHVKFAAYSIDHPILMARKPRFKIVTDGKESPEEALEKAAQRVFDRARAVLEAWKSAIEG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFI44_MOUSE
Sequence: MAMRTRLTWQQEKCLQNYFGGKRFCLLYKASVQKFSHQNLLCTCENQGPTMIVVYSEKCVIGMYLKEGFQGKDVSITIFALQETGFSLCAKGPDSPYLLFHKRKTNDFSILLDEKAVIVSSAICKMLQLTARNNVIPIQECEAFRCEELLDERKTRGIAVLHSNLLQALRDYKPYGDLVQQTRVLLLGPIGAGKSSFVNSVKSVFKGSITHQILVGCDEDGISDKYRTYSIKAKDDSDPLPFILCDSLGLGENAGLHTDDVWHILKGHTPDRYQFDSMKPITSNHPNYTHDPLLKDRIHCVVFVFDINSFEMHSSELVAKIKKIRRDLIKHGILHLALLTHVDSLDLITKEDMTDIYNYSPVKSKLEAFHGVFGFALSDILVVSNYVSEWQLDPVKDMLILSALKEILYTANEFLEDLPLNK
What is the function of this protein?
This protein aggregates to form microtubular structures.
What are the official names of this protein?
Interferon-induced protein 44, Microtubule-associated protein 44.
What is the protein family that this protein belongs to?
Belongs to the IFI44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA11_ANTEL
Sequence: GIACLCDSDGPSVRGNTLSGTYWLAGCPSGWHNCKSSGQLIGACCKQ
What is the function of this protein?
Produces a positive inotropic effect in mammalian heart muscle.  Modifies current passing through the fast sodium channel (Nav) in neuroblastoma cells, leading to delayed and incomplete inactivation.  Paralyzes the shore crab (C. maenas) by tetanic contractions after intramuscular injection.
What are the official names of this protein?
Delta-actitoxin-Ael1b, Delta-AITX-Ael1b, Toxin APE 1-1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: AROA_PICTO
Sequence: MNVRISGEFRPGVINAPSSKSFSQRYILYSAFSNIPVTLKNVSFSDDERIALEIARACGADIEFNDSLTIKPDFRCPDEINAGESGTSLRLATGLLAARRCKTFIHEEASLLKRPLDDLIKTLSEKNVVFNNLDNGIMIDASNSIPSDSIIDGGRSSQFVSSMMMYHSLTSGSLKALNIVSNDYIKITIKTLNDFGISVYSSNGFFEFGKTLMKGNKICIEGDYSSAAFWIVLGLFKGDIEIKNLKSDSCQPDAAIINIINGISERKIDIYNNKIVVHKTRFLGDLYIDVDKNPDLAPPLSIIGIFSDVAVHILNYRRLEIKESNREENIISMARSFGALIEKNDNEMVIRRGKISLPERISFSDHRMIMSSIIAGLISSGDILYENIENINKSYPGFLNDLSNLGYYILK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HJC_SULIR
Sequence: MNAKKRKGSAVERNIVGKLRDKGFAVVRAPASGSKRKDPIPDIIALKSGVIILIEMKSRKDKEGKIYVRREQAEGIMEFARKSGGTLFLGVKKPGVLKFIPFDKLRRTETGNYVADSEIEGLDLEDLVRLVEAKVSKTLDNFL
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination.  Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
What are the official names of this protein?
Holliday junction resolvase Hjc, Hjc.
What is the protein family that this protein belongs to?
Belongs to the Holliday junction resolvase Hjc family.
Protein: POTA_SPICI
Sequence: METNILELRNISKQYDGKVVLKGINLNIKEGEFVTLLGPSGCGKTTTLRIIAGFEQPNSGELLFLGKDYLKTPVHKREVNTVFQNYALFPHLTVFDNIAYGLKVKRNKYDVIETEVKKFLQLVGLEGFEDKSVEQLSGGQRQRVALARALINKPRVLLLDEPMAALDVKLRKKMQAELKALQGEIGITFILVTHDQEEALTLSDRIIVMNDGAIQQVGTPAEIYNEPENLWTAQFIGDSNIISNAIFIKDNLVTIDGKKIVCVDRGFGENENQIDIIIRPEDIDIVPVGKGFFTGTVKRVNFKGVHWEIIVKCKERKYLIHSTDRVEEGDQVDISWNVEDIHVMWKEIDD
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ABEC4_RAT
Sequence: MEPLYEEYLTHSGTIVKPYYWLSVSLNCTNCPYHIRTGEEARVPYTEFHQTFGFPWSTYPQTKHLTFYELRSSSGNLIQKGLASNCTGSHTHPESMLFERDGYLDSLIFHDSNIRHIILYSNNSPCDEANHCCISKMYNFLMNYPEVTLSVFFSQLYHTENQFPTSAWNREALRGLASLWPQVTLSAISGGIWQSILETFVSGISEGLTAVRPFTAGRTLTDRYNAYEINCITEVKPYFTDALHSWQKENQDQKVWAASENQPLHNTTPAQWQPDMSQDCRTPAVFMLVPYRDLPPIHVNPSPQKPRTVVRHLNTLQLSASKVKALRKSPSGRPVKKEEARKGSTRSQEANETNKSKWKKQTLFIKSNICHLLEREQKKIGILSSWSV
What is the function of this protein?
Putative C to U editing enzyme whose physiological substrate is not yet known.
What are the official names of this protein?
Putative C->U-editing enzyme APOBEC-4, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: WTR22_ARATH
Sequence: MARTVSLWRREAVFLTAMLATETGVVGISTLFKVATSKGLNLYAFLGYSYLLASLLLLPSLFFTDRSRSLPPLSLSILSKIGLLGLLGSMYVITGYIGIEYSSPTLASAISNITPALTFILAIIFRMEKVSFKERSSVAKVMGTILSLIGALVVVLYHGPRVFVASSPPYINFRQLSPPLSSSNSDWLIGGALLTIRDIFVSVSFILQAKIMSTYPAAFTVSFLYIVSVSIVTSMIGLVVEKNNPSVWIIRFDITLITIVTMAIITSVYYVIHSWTVRHKGPLYLAIFKPLSILIAVVMSAVFLNDSLYLGCLIGGLLITLGFYAVMWGKANEEKDQLLLVSGKERTPLLLNG
What are the official names of this protein?
WAT1-related protein At3g28100.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPE_PSECP
Sequence: MNTPAVRFAARTVRVKAPGKINVSLDVGPRRPDGYHSVASVYLAVSLYEEVAATSTETPGITVSLSPDSTLDLDAVDIPLDASNLAYRAAAIMADVSEHATGVHLEITKRVPVAGGMGGGSADAAATLLACDALWNSGLSREELAHLAAELGADVPFSLLGGTAVGLGVGDQLSPALAKAKTHWVLVTADFGLSTPEVFRTLDRLREAEGVDADEPTGVDPNILAALRGGDADALSRILVNDLQRASIELAPSLRDTLGIGESHGAIAGIVSGSGPTVALLADDSVAAEALAEDLQHQGLSALAVHGPVPGARIISDTLL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ATPA_NEOSM
Sequence: MSLDVNASEVLRIIKEKIKDFDQQIFSEEIGEVISVKDGVVIACGLENAEFNEKVVFPNGEIGLIQSIEYDHVGIVILTNTQDIKEGDTVRRTKEALRIPVGKKLLGRVIDPLGNPLDGAGQIFADAYSPIEVKAPGILDRQSVKEPLQTGIKVIDLLIPIGRGQRELIIGDRQTGKTTIALDSIINQRDINKNLPDEKKLYCVYVAIGQKCSTVARIMKTLQEQGAMDYTTIVLAGASDSAQSQFLAPYAGCSIGEYFRDNGMHCLIVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDVFYIHSRLLERAAKMSDKHGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETELFNKGVKPAVNVGLSVSRVGSAAQIKAIKQVARSIKLELAQYREMEAFAQFGADLDETTQALLEKGKKLTELLKQNQHETLPVEEQVVLMFAANEGYFDNIDVTGISTAAKNLLGSFRLYHRDLLEDIKEKSIIGDLASLSSALQGCKTTNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR11_STIHE
Sequence: MSKQIRKNVKKPRKKIYRGVVYIQTTQNNTIVTITNIKGDAVCWSSAGSCDLKGRRKATAYAAKLAAANAAKKARREFVLKEAKVLITGPGAARDTAIHEIHKAGIKLTILREKSGVPHNGCRPPKRRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IL6_NEOVI
Sequence: AENNLKLPKLAEKDKCFQSQFNQETCMTRITTGLQEFQIHLKYLEANYEGNKNNAHSVYISTKHLLQKLRPMNQVEVTTPNPTTDSSLQALFKSQDKWLKHVTIHLILRSLEDFLQFSLRAIRIM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_ECO8A
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HEM3_ROSCS
Sequence: MRNSLTIGTRASKLALVQTHMIRDALQAAHPGLTVAVERITTRGDIILDRPLNAIGDKGLFVVEIEEAMRAGRVDLAVHSAKDLPSTLPPDMTLAVCPRRADPRDALVAQPGMTLASLPHGARVGTSSLRRACQLRALRPDLTLLDLRGNVDTRLRKLREGQYDAIVLAAAGLKRLGLEEVITELLEPDVLIPAVGQGIIGVEARAGDDEVLRLLAPLDDPAARAAITAERAFLARIGGGCRVPVGALALLEGDELLLYGMIGALDGRMVRGMRSGSASDPAGLGSALAEELLDAGGQALLAG
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PCXA_SYNE7
Sequence: MAFFAGISDWVAQRLQRNSETARLDLERAYEAALYITALETEYASGRSLRRLPSQLSARQQTSLQAELRQTLRSLRHYRQRYRRHQPVQLQAGLALGRPGMGMPTIAHEKLQLIEQVLARYGQPTVHSSNPDDSQLMTSKNNSKPVPDPESDDEYLISQTSFLPRSIFGAFADLRQQLDPKAEDQIVQNFRSRKGKTLIALRFVLLLVLVPLLTQQISKSFIVGPIVDRLRSQDPEAIFLNFQMEEEAFVKLNQYQQLLRFQHYLKEAPPLTEAEIDERVREKAEEIAVEYRQESSNAIKNIFADLISAAAFAILLISSQEEIQLLKSFIDEVVYGISDSAKAFIIILFTDIFVGFHSPHGWEVILESISRHFGIPENRSFIFLFIATFPVILDTIFKYWIFRYLNRISPSAVATYRNMNE
What is the function of this protein?
Involved in light-induced Na(+)-dependent proton extrusion.  Also seems to be involved in CO(2) transport.
What are the official names of this protein?
Proton extrusion protein PcxA.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BDBB_BACSU
Sequence: MNTRYVKSFFLLLFFLSFFGTMASLFYSEIMHFKPCVLCWYQRIFLYPIPIILLIGLLKKDLNSIFYVVFLSSIGLIIAFYHYIIQLTQSKSVVCEIGTNSCAKIEVEYLGFITLPLMSSVCFALIFGIGLKLIIKSKKLKQNQHVYN
What is the function of this protein?
Important but not absolutely essential for the production of the lantibiotic sublancin 168, it may also be required for the stability of other secreted proteins.  Not required for competence for DNA uptake.
What are the official names of this protein?
SPbeta prophage-derived disulfide bond formation protein B, Disulfide oxidoreductase B, Thiol-disulfide oxidoreductase B.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1164_METJA
Sequence: MMIMREILISECIELLRSHKFIVSKPLGRSCFDMVASKEDIRLILKILKNIDSLSRDQSKELKKISKILHGTPLIIGIRTRNAPMEHGVVYDRYNIKAVTFETFRDYLEGSPPMVYANRGGFFVKIDGKVLKEVREAMGISVGKLAEVAGVSRKAIYKYETQMANPSVDVALKIEEFLDVPLVKGIDLFEPVDDEDVENKLENLEDFKKEAINFLNELGFKSFVVEKAPFDAVAEKDMDNNLNILLTNIEEKDNEEVKRKALFVRELSRLLDGYSLLILEEKEKEYKNLPVVSIEELKKMDDALELIEHIKSMLRDIR
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein MJ1164.
Protein: STRAA_CHICK
Sequence: MSNFLPDSSCYELLTIIGRGFEDLMVVNLARYKPSGEYVTVRRVNLEACTNEMVTFLQGELHVSKLFNHPNIVPYKATFIADNELWVVTSFMAYGSAKDLICTHFMDGMSELAIAYILQGVLKALDYIHHMGYVHRSVKASHILISVDGKVYLSGLRSNLSMINHGQRLKVVHDFPKYSIKVLPWLSPEVLQQNLQGYDAKSDIYSIGITACELANGHVPFKDMPSTQMLLEKLNGTVPCLLDTTTIPADELTMKTSRSSANYGLGESTAVSNVRAANGESTLHPYLRTFSSCFHNFVGQCLQRNPDFRPSAGALLNHPFFKQIKRRASEALPELLRPVTPITNFEGTRPQDPSGILGWCQTWSSWMWMTGNSRKTKTALGSGGAFWTL
What is the function of this protein?
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1.  Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
What are the official names of this protein?
STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ATPFD_MYCSS
Sequence: MSTFIGQLIGFAVIVFLLVRFVVPPVRRMMTAQQETVRRQLEESSTAANKVAQADQQHAKAVEEAKADARRVVDEARSDAEKIAEQMRAQADAEVERIKVQGQAQVQLLRQQLIRELRSHLGTESVARARELVRDHVSDDDNRSATVDRFLDELDAMAPSDAALDDAVGSRMRSTSRESLKALVSRFDELTADVDADGLTSLGDELAAVAKLLKTEPVLGKHFGEPTEDGEGKANLAEAVLSGKISDTALEVVKAAVAQRWSDESDLDYAVRHTARLALLVRAERNDETSEVEDQLFRFSRILDSESRLSGVLSDYTTPVDGRIGLLDRLLGDQAGETTRALLAQTVELLRGERADEAVRELAELAVARRGEVVAHVNAAAELSDAQRTRLAEVLGRIYGRPASLQLHIDPDMLGGLTIAVGDEVIDGSLASRLASAETQLPD
What is the function of this protein?
This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta).  Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0) (By similarity).
What are the official names of this protein?
ATP synthase subunit b-delta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MES3_CAEEL
Sequence: MTPATAEVKVGGRKRKNDEPVFIKTKQSRSARREEEKENLLNKSLPSTPTSSEAGSSRESSNPVTSSSRRKNPPTKLENIQKTLPTCSDGLEIRNYVKKYGLPEDNKFLVRNVFDKQLLFGKKYVCRRRVIKSIDEFFPRLKTDAHRENGLYNFCTLQFMKISSWGSSMDEKIYVTSAAIVQSYVIIVDDNDSVTCIENGISVIPMANRTLPSISYNSSNVKNITLTGPELKKAKNVYLAVIVKRKTPKLGENRVGTRGKSTRASFETAASSENFQQLVRFGCTLMYDKDAEINCLNDGVQRIILLDREEKPAYLKIFGKADEPELENAWMNNVKHLEFISDTNYNKEDSHLARLIFSSNTHNYFDRPDISKFSPWQPRSRRTTLKSGISVEPGTSCDEDCGSQYEDTITLKQLLLGTKKLCGRRKRHLTRLTSRWPCFSVDPTKINSYFNETGVTLLENSCSYRPGTQRSIPIKPTRVIRVREETPVSVPIEVITIEDDSDDSPCFSARNRAPGGTRKYGLDFIQSSGHMPYIRYVYMNRANDLVPQLNGEENGKIEGLMEAYPMNNAHMYSDIEFLRKEKLNLPKNAQKYGEMTILDYPLTKTETDEYNKKMSVMNVKDFAVKPRKPIPTVGNTTLSLDLEGCPISTFSEIFFPSGKTELFNILCRHFYSEAGQRPGCFSAQWKSRVLTGFINKYHQYIFDMKLNSLFEKQINLIAMVSPDWKLEDFELPMVRYKQLKKEWKNRQRDIPSSN
What is the function of this protein?
Component of a Polycomb group (PcG) complex.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  In association with the nfya-1-NF-Y complex, may play a role in repressing the expression of the homeobox protein egl-5 in tissues such as the head (PubMed:17574230).  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  The mes-2/mes-3/mes-6 complex may participate in the global inactivation of the X chromosomes in germline cells.  The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility.  This complex is required to exclude mes-4 from the inactivated X-chromosomes in germline cells.
What are the official names of this protein?
Polycomb protein mes-3, Maternal-effect sterile protein 3.
What are the subcellular locations of this protein?
Nucleus.