PharMolix/UniProtQA huggingface dataset:
Protein: SCP2D_BOVIN
Sequence: MWKRIDHQLKIKAGDGPQAGQFKELGPGREPAVPHPLSLSEFQTVPVFEDISQHVKEVGSQLVKKVNAIFQLDITKDGKTVHQWTIDLKNGSGDTYRGPARLPADTVFTIPEPVFMELILGKMNPQKAFLAGKFKVSGKVLLGQKLERVFKDWAKW
What are the official names of this protein?
SCP2 sterol-binding domain-containing protein 1.
Protein: VATB_STRGC
Sequence: MSVIKEYRTVSEVVGPLMIVDQVAGVHFNELVEIQLHDGSKRQGQVLEVQEDKAMVQLFEGSSGINLEKAKVRFTGRPLELPVSEDMVGRIFNGMGKPIDGGPAILPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLANDPAIERIATPRIALTAAEYLAYEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYPGYLYTNLSTLYERAGRLVGKKGSVTQIPILSMPEDDITHPIPDLTGYITEGQIILSRDLYNSGYRPPINVLPSLSRLKDKGSGEGKTRGDHAATMNQLFAAYAQGKQAKELAVVLGESALSETDKLYVRFTDRFEQEYINQGFQTNRTIEESLDLGWELLSILPRTELKRIKDDMIDQYLPQTKEEER
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RL34_BORRA
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKSGRLILARRRAKGRSKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CYADH_CATRO
Sequence: MQIITCKAVVCWAAGEPPVVEEILVEPPRSGEVRIKILFASLCHTDVLACKGFPTPMFPRVLGHEGVGVVECVGEGVSELREGDVVIPTYLGECGECENCESGRTNLCRTYPLQAFTGLMPDGSSRMSSAKGGEMLYQFLSCSTWSEYTVIDANYAVKIDSRIPLPHASFLSCGFTTGFGATWKEAKLQEGSSTVAVLGLGAVGLGAVEGARVQGVTQIIGIDINDNKREKGEAFGMTHFINPKKDNNKSISELVKELTKGQGVDVCFECTGVPDLVNEALESTKIGTGNMIMLGAGTQKSMTINFVSLLGCRTFKYSVFGGVKVQSDLPLIIQKCLNKEIQKIEQLLTHQVQLEDINRAFELLKEPDCVKVLITL
What is the function of this protein?
May be a positive catalyzer of strictosidine production by assisting secologanin biosynthesis, thus being involved in monoterpene indole alkaloids accumulation.
What are the official names of this protein?
CYP enzymes assisting alcohol dehydrogenase, CrCYPADH, Alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein: RLMN_BACMK
Sequence: METTVKKQKKNLETKKPSIYSLQLHEMQDWLKEQGEPKFRAGQIFDWLYKKRVKNYEDMSNLAKGLRDKLSNSFDITTLNTLVKQTSSDGTIKFLFQLYDGYSIETVLMRHEYGNSICVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVAQVVEVQRALDETEERVSSLVVMGIGEPFDNYDNLMSFLRIVNHEKGIHIGARHMTVSTSGIVPKIYKFAEEDMQINFAISLHAANTEIRSKLMPINRAYKLPDLMEAVKYYVNRTGRRITFEYGLFGGENDQVEHAEELAALLKGVKCHVNLIPVNYVPERDYVRTPREQIFLFEKTLKDRGVNVTIRREQGHDIDAACGQLRAKERKEETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_GUNCH
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ARC_JONDD
Sequence: MTETHNDPEELARRVASLSAQNERLAQILVEARSKIVGLQQQIDDLAQPPSTYATFIRSYSDGTADVMVQGRKMRLTSLPAAMVSTARPGQQVRLNEAMAIVETMTYDHTGELVTVKELIGTHRAMVVGRGDDERVVNLAGSLIGRDGPTIRTGDSVLVDLKAGYALEKIDKSEVEELVLEEVPRVAYEDIGGLSRQIDTIKDAVELPFLHPDLYREHGLKAPKGILLYGPPGCGKTLIAKAVAHSLAQTVGQGNNTPTDDTRGYFLNIKGPELLNKYVGETERQIRLIFTRARDKAAQGHPVVVFFDEMESLFRTRGTGLSSDVETTIVPQLLAEIDGVERLDNVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAALDIFSKYLTPDLPIHPVDLAEHGGNAQDAVTAMGQRVVEHMYATTPDNQFLEVTYASGDKETLYFKDFSSGAMIQNIVDRAKKAAIKGYLSHGTRGLQVEHLLAACDDEFQENEDLPNTTNPDDWARISGKKGERIVFIRTIVQRKGEGKNPTPAKAIETPHNTGPYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: NRDI_STAA2
Sequence: MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: GHRB_ECOSE
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_STRR6
Sequence: MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGVLIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSSVAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDLEGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RSMA_CHLCV
Sequence: MSRSSPDQLTRFLAQVQGRPKKGLSQNFLIDGNILRKILAVSCVEAGDWVLEIGPGFGALTEVLVNQGAHVVALEKDPMFEETLKQLPIDLEITDACKYPLSQLEEKGWQGKGRVVANLPYHITTPLLTKLFLEVPNQWKTVTVMMQDEVARRITAQPGGKEYGSLTIFLQFFADVRYAFKVSPGCFFPKPQVSSAVVHMTVKETFPLETSLHQKFFSLTRAAFGQRRKLLANALKDLYPKELVFSALNQLNFSEKTRPETLSLNEYLQLFHLLSSNA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2683_LISMF
Sequence: MRGMGNMQGMMKQMQKMQKEMAKAQADLEAQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDPEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein LMOf2365_2683.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RTC5_DEBHA
Sequence: MGQVLSKDNEDEANLNVTQKQFTKDKVLEYFNIQNHLQFRPVEIRAITSKLGIKNIKEKSDVTLNDLIYLLKIIKDEDIEGIDHNIKHVLNILSNSFTVIGNFPFLQSETTPKLSIESLMKSALFHTGRYKRLLTAEYDYLKLVFISLSGINKTYLEEKTSSSPSSSDDKEDTLYNLDVMGFSSEDEDSILSRKIKWNTFNVIQSFDDIDLDSIYVGAYDLLKLLTFFLILSSVPEMSHTQMQDHLSKSIARWSEFETYCLSIIRYINLDINVKNIKSTKISYEEFKRGISNGFPLFFSNAWMKIFKNGILSSISTTDVANSNNAPGSHGDANDNEVPKVHKKTPNFVESKLINDASISVISMCLKNMKSNLSITTQNLIKLYAGSESGFSIRSLESKIFKWQAPTLLLVSGKRVKNKTMKHNNRYIQFNEMYPSYFRSSESPKKDWQDDNDKMTYAVIINSPWKNSNKNNFGDEDTVILNLSPRFDFYKSVHNPVLNGKSIYFNNLGMGLGFGNSQPINKNTVKKFLPGDISLTIEANLEFAIFRHISSPNSNGASFFQKSKQNEISVQDFEDRFMISDLEVWGIGSTKELEEQRKQWAWEEKQAEARQSVNLRGLGEERAFLEMVGLVGNHSANGGSM
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_CAMJ8
Sequence: MQIYVSGIHTDVGKTHFSAAFCANFNYDYFKLIQAGTPTDSEFIAKFSPKTKIFKEGIFLQTPASPHLGKIKEKLDYKALDIILPKSKNLLIELAGGLFSPMDENYTMIDFVNIFKHPTILVAKYYLGSINHILLSIEALKQRNINLLALVMMGKKDILQDDFIKNYAKIPIINLDFFDENSILNKDFKEQMQEILQLKIP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_MARBO
Sequence: XIMVEKDPVKTSFEKWAQPGHFSKALAKGPSTTTWIWNLHADAHDFDSHTNDLEDISRKIFSAHFGQLGIIFIWLSGMYFHGARFSNYEAWLNDPTHVKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQLWRASGITSELQLYCTAIGGLIFAGLMFFAGWFHYHKAAPKLAWFQNVESMLNHHLAGLLGLGSLAWAGHQIHVSLPINQLLDAGVDPKEIPLPHEFILNRELMAQTFPSFAKGLIPFFTLDWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAVLFLVAGHMYRTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAHHMYAMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTQYNNLLDRVIRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWVQNTHALAPGSTAPNAAASTSPTWGGSDLVAVGGKVALAPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGSISEEGVVNHITGGNFAQSSTTINGWLRDFLWAQASQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPVTQPRALSIIQGRAVGVAHY
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FLGH_GEOSL
Sequence: MKRLAMSIICLALAGCAVEKTEVRTPTFDEQLRPAPPSYANGSIWQASTTGLAVDHKARSRGDIITVLIVEQASASKEATTDTERKAEVSASVPYLMGLEKSSTLFSKLTNANPNNLLGASTNSKYEGSGATTRKENLLATMTAKITDVLPNGNFLIEGRRNVKVNNEDQILVLQGTIRPRDVSPDNTISSTMIADARISYTGNGVISDRQRPGWLMNILDYIWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ODO1_STAS1
Sequence: MSNESQVSEAPVNFGANLGYVLDLYDIYLDNPSAVPEDLQVLFSTIKNGEANIATNTEGQSNVTKGDSTIKRVMRLIDNIRQYGHLLADIYPVNRPQRENVPKLNMEDFNLDQETLESISAGIVSEHFKDIYDNAYEAIVRMEKRYKGPIAFEYTHINNNRERVWLKRRIETPYKATLNDNQKIELFKNLAHVEGFEKYLHKNFVGAKRFSIEGVDTLVPMLQQTLRIASDEGIQNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHIDPMKFLPEDGSLQLTSGWTGDVKYHLGGVKTTQSYGSEQRISLANNPSHLEIVAPVVLGKTRANQDTTDKPGAVTTEFKKSMPILIHGDAAYPGQGINFEAMNLGNLEGYSTGGSLHIITNNRIGFTTEPEDGRSTTYSSDVAKGYDVPIMHVNADNVEATIEAIEIAMAFRKEFNKDVVIDLVGYRRYGHNEMDEPSITNPLQYYEIRKHESVDILYGKQLVNENIISENQMNQIFDDVQNTLRAAHDKIDKNDKMDNPDMQKPDSLAEPIQTKDEEVSYEQLKEINDAMLSYPSDFNVLKKLNKVLEKRREPFESEDGLVDWAQAEQLAFATITQNGRPIRLTGQDSERGTFSHRHAVLHDPDTGAQYVPLHNVPDQKATFEVRNSPLSEAAVVGFEYGYNIQNKSCMTIWEAQYGDFSNMAQMIFDNFLFSSRAKWGERSGLTLFLPHSFEGQGPEHSSARLERFLQLAGENNSTIVNLSSSSNYFHLLRAQAANLGTQSMRPLVVMSPKSLLRNKTVADPISKFTSGKFEPILPEAHDKASVKKVILASGKMFIDLKEYLTKNPNKSILLVAVERLYPFPADEIDALLSELPNLEHVAWVQEEPKNQGAWSFVYPYLKELTTDKYDLSYHGRIQRSAPAEGDGEIHKLVQNMIIEQSTNIN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RPOC_LACP7
Sequence: MPTEMINESVKDITYDAIKIGLASPEKIREWSRGEVRKPETINYRTLKPEKDGLFCEKIFGPNKDWECHCGKYKKIRYKGVVCDRCGVEVTKASVRRERMGHIELAAPVSHIWYFKGIPSRMGLILDLSPRTLEKVLYFASYIVLDKGTTDLQYKQVLNEKEFREAYDKYGDRFRVGMGAEAIMELLEAIDLEKESKDLKRGLKESTGQKRARIIKRLEVVEAFRESGNKPEWMIMTVVPVIPPDLRPMVQLDGGRFATSDMNDLYRRIINRNNRLKRLLELGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKIYQCGLPKEMAIELFKPFVMKELVAKGTAHNIKSAKKMVERLQPEVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCTAFNADFDGDQMAVHLPLSVEAQAECRFLLLSPNNLLKPSDGGPVAVPSQDMVLGIYYLTLQKPGDIGEGKYFKSVNEAILAYENGVISLHAMIKVRRTGLNAEGVEESRTIESTVGRFIFNEIISQDLGFVDRSKPENFLALEIDFHTGKKQLKKILEKCINTRGATQTAETLDAIKSLGYKYSTRAAMTVSISDMTVPEAKKDIIERAEKQVEDIAKNHRRGLMTEEERYKAVIETWKEADDEITKELLSGLDKYNNIFMMADSGARGSDKQIKQLAGMRGLMADTSGKTIELPIKANFREGLDVLEYFISAHGARKGLSDTALRTADSGYLTRRLVDVSQDLIIREVDCGEGTDEIPGMEIKAFMDGKEVIEGLEDRIIGRYACETIYDDNGELIVKKNHIITPKRAARIVASKAFEDPNATIKIRTVLSCKSHIGVCAKCYGANMATGEAVQVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVEELFEARKPKGLAIIAEFGGTVTIKDTKKKREVIVTRTSNDTLESKAYLIPYGSRIKVMDEQVIEAGDELTEGSVNPHDILKIKGVRAVQDYMIQEVQRVYRLQGVEINDKHIEVIVRQMLKKVRVENNGDAEFLPGTMVDILEYNDVNESLAAKGLEQAEGKQVMLGITKASLATNSFLSAASFQETTKVLTEAAIKGKIDPLIGLKENVIIGKLIPAGTGMKHYRNVKLDTDQNQEITFSEDEFDNGNYEGNFSGNDFKQNFYENEDFNSDEEVSFTEDEYFEDEENDLSTENFDDLKFSEEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SIA8D_BOVIN
Sequence: MRSIRKRWTICTISLLLIFYKTKEMARTEEHQETQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHSVEGGKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISQDLHSLLPEVSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKLKVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKCIKQ
What is the function of this protein?
Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells.
What are the official names of this protein?
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8D, Polysialyltransferase-1, Sialyltransferase 8D, SIAT8-D, Sialyltransferase St8Sia IV, ST8SiaIV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CRCB_XANC5
Sequence: MNAPVWWQQLLLAMTGGALGSGLRFAIGASLIQRFGTGFPWGTLTVNLLGSFVAGVLLVWLDARGPSSWPLRALLIVGVIGGLTTFSSLMMECLVFARTDRSTMIGIYLAVTLLAGLALVVAGARTGQWLVAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_SOLM1
Sequence: MSVAADMEVMARKAKEASRAMAAASGAAKDAFLAGLAGLLETRREGVLAANAADLEKARAAGMDAPRLDRLTLTPAVMDGMAKACREIIALPDPVGAIESMRPRPNGLLVGCMRVPLGVICMIYESRPNVTIDAAILCLKAGNAVILKGGSEALASNLALAGLLREALEASGLPADAAQLVPTADRAAVAALCKLDELIDVMIPRGGEGLIRAVVSQATMPVLKHYKGVCHAYIDSGADEARAETIVVNAKAQRPGVCNALECLLVHVDAAPTFLPRIGDALRRVGVTMRACPRSLPLLGEGAVAAMPEDFGHEFHDLILAVKVVDSLDEALTHIHRHGSGHTEVICTENHDRAMDFLRRADASMVGVNCSTRFNDGGELGLGAEIGISTSKLHSYGPMGLVELTSAKFVVLGQGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGM2L_HUMAN
Sequence: MAENTEGDLNSNLLHAPYHTGDPQLDTAIGQWLRWDKNPKTKEQIENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERCFSDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFSRYVPTPFVPYAVQKLKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWNGSWNDNLVDTSPLKRDPLQDICRRYMEDLKKICFYRELNSKTTLKFVHTSFHGVGHDYVQLAFKVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARVVLATDPDADRLAAAELQENGCWKVFTGNELAALFGWWMFDCWKKNKSRNADVKNVYMLATTVSSKILKAIALKEGFHFEETLPGFKWIGSRIIDLLENGKEVLFAFEESIGFLCGTSVLDKDGVSAAVVVAEMASYLETMNITLKQQLVKVYEKYGYHISKTSYFLCYEPPTIKSIFERLRNFDSPKEYPKFCGTFAILHVRDVTTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVATLRTSGTEPKIKYYAEMCASPDQSDTALLEEELKKLIDALIENFLQPSKNGLIWRSV
What is the function of this protein?
Glucose 1,6-bisphosphate synthase using 1,3-bisphosphoglycerate as a phosphate donor and a series of 1-phosphate sugars, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1-phosphate, as acceptors (PubMed:17804405).  In vitro, also exhibits very low phosphopentomutase and phosphoglucomutase activity which are most probably not physiologically relevant (PubMed:17804405).
What are the official names of this protein?
Glucose 1,6-bisphosphate synthase, PMMLP, Phosphoglucomutase-2-like 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PGLR2_ASPTU
Sequence: MHSFASLLAYGLAASATLASASPIEARGSCTFKTAAAAKAGKAGCSTITLDNIEVPAGTTLDLTGLTSGTKVIFEGTTTFDYEEWAGPLISMSGKDITVTGASGHLINCDGARWWDGKGTSGKKKPKFFYAHGLDSSSITGLNIKNTPLMAFSVQADDITLTDITINNADGDTLGGHNTDAFDVGNSVGVNIIKPWVHNQDDCLAINSGENIWFTSGTCIGGHGLSIGSVGGRSNNVVKNVTIEHSTVSNSENAVRIKTVSGATGSVSEITYSNIVMSGISDYGVVIQQDYEDGKPTGKPTNGVTITDVKLESVTGTVDSKATDIYLLCGSGSCSDWTWDDVKVTGGKKSTACKNYPSVASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase II, EPG-II, Pectinase 2, Polygalacturonase II, PG-II, Polygalacturonase X2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIKR_RHOPT
Sequence: MHRVTITLDDDLMEKLDAIIAARGYQNRSEAIRDLARIGIQQTAAETTSGHCVGAMVYTYDHSKRDLPRKLTQSFHHHHDLSRATMHVHLDHDQCLEVTILDGNASELQHFADHIFAERGVRYGRLVTIPAEPPEAHEHHHEHDASS
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: PDXK_BOVIN
Sequence: MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYSHWKGQVLNSDELQELYDGLKLNSVNQYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVMGDQRDGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHTQEEALEVMDMLHSMGPDTVVITSSDLLSPRGSDYLMALGSQRTRAPDGSMVTQRIRMEMHKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDIESPEIVVQATVL
What is the function of this protein?
Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (By similarity).  PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions (By similarity).
What are the official names of this protein?
Pyridoxal kinase, Pyridoxine kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSN2_XENLA
Sequence: MIKLSDSEDEECNERTSLITSESPPLPSYQDGVQASEGLETSYHRERQPDSTQNNEDVPNGRTSGADAYNSETTVENEEEELTLKYGARHVIMLFVPVTLCMVVVVATIKSVSFYTEKDGQLIYTPFSEDTTSVGERLLNSVLNTLIMISVILVMTIFLVLLYKYRCYKFIHGWLILSSLMLLFMFTYIYLSEVFKTYNIAMDYPTLFMVIWNFGAVGMICIHWKGPLQLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLLAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMMWTVGMADSATADGRMNQQVQHIDRNTPEGANSTVEDAAETRIQTQSNLSSEDPDEERGVKLGLGDFIFYSVLVGKAAATASGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNIVRPFMDTLASHQMYI
What is the function of this protein?
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (By similarity).  May play a role in negative regulation of apoptotic cascades during oogenesis and embryogenesis, and in developmentally matured tissues such as brain tissue.
What are the official names of this protein?
Presenilin-2, PS-2, Presenilin beta, PS-beta.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ENO1_CANGA
Sequence: MSVTKVHARTVYDSRGNPTVEVEVYTKDGMFRAIVPSGASTGSHEALELRDGDKSKWEGKGVTKAVSNVNDIIGPKLIESKLDVKDQKAIDEFMIKLDGTKNKSKLGANAILGVSLAVARAGAAAKGVPLYQHIAELADMKKEPYVIPCPFFNVLNGGVHAGGNLALQEFLIAPVGAESFHEALRLGSEVYHKLKALAKKRIGSSAGNVGDEGGIAPSLSTPFEALDLIYDAIKEAGHEGKVKIAMDPASSEFFQGDKYDLDFKNPHPDAKNKLSGAQLGDYYKTILEKYPIVSLEDPFAEDDWEAWTNFFPKAGVQIIADDLTVTNPERIQTAIDKKTADCLLLKVNQIGSLTESINSAKLAYGAGWGVQVSHRSGETEDTFIADLVVGLRTGQIKSGSLARSERLAKWNQILRIEEELGASNTIFAGAKFHKGQLL
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2323_ALKCK
Sequence: MTIKLINIGFGNIVSANRIISIVSPESAPIKRIMQEARDRNMLIDATYGRRTRAVIVTDSDHVILSAVQPETVAQRLHTKEDGVEDA
What are the official names of this protein?
Putative regulatory protein ABC2323.
What is the protein family that this protein belongs to?
Belongs to the RemA family.