PharMolix/UniProtQA huggingface dataset:
Protein: ATG10_GIBZE
Sequence: MSIENFPSLNSEEFTEACHHLDRQYCQAPLGSERARWKLRLCNALCTDFSYGGGFTTYVQIRRPLEFDLDHGDLSLDLDGFSFSDEKGPHVSIAEDKDMLDAEEADEAALIRQRARPEIAMVEYEIHLHPTYRVPCLWFTLRNLPADEPAFDVDTVFRRLVPDEYKAGLRTLGNVGGISADHHPITGVPSFFVHPCLLGDAISKFECDRTNYLMIWLGLVGGCVGLWVPKEMAMQ
What is the function of this protein?
E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy (By similarity).  Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5 (By similarity).  ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS) (By similarity).  Likely serves as an ATG5-recognition molecule (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the ATG10 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RUVA_ECOLI
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
An in vitro resolvase system that forms and processes HJ has been reconstituted with DNA substrates, RuvA, RuvB and RuvC.  RuvA-RuvB increases the rate of strand exchange (branch migration), dissociates the RecA filament and allows RuvC to cleave in both orientations at the cruciform junction (PubMed:9160752, PubMed:10421637).  HJ-RuvA-RuvB-RuvC complexes resolve Holliday junctions and also undergo branch migration, providing evidence for a coupled branch migration/HJ resolution reaction (PubMed:10421637).
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In 15% of cell localizes to discrete nucleoid foci (probable DNA damage sites) upon treatment with mitomycin C (MMC) for 2 hours.
Protein: PURA_MYCLE
Sequence: MPAVVLIGAQWGDEGKGKVTDLLGGRAQWVVRYQGGNNAGHTVVLPTGENFTLHLIPSGVLTPGVTNVIGNGVVVDPGVLLSELQGLEDRGVDTSQLLISADAHLLMPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARMGIRVADVLEPGELTHKIEAALEFKNQVLVKIYNRKALDLAQVVETLLEQAQQFRHRITDTRLLLNDALEAGETVLLEGAQGTLLDVDHGTYPYVTSSNPTAGGAALGSGIGPTRIHTVLGILKAYTTRVGSGPFPTELFDENGEYLAKTGSEIGVTTGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYQIAGVRTHDMPITQSDLARAEPIYEELPGWWEDISGAREFEDLPAKARDYVLRLEELAGAQVACIGVGPGRDQTIVRCDVLRSRR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT35_PICGU
Sequence: MVANTSMRLNQVAPVPIQLEDHGPNQLEPTHISDVLVGEHHTIKGENGQSYVVWAIRIIVNDSIYSSIVLYKRYREMEAFRNKLLDEFGNEIPPLPPKDSMSLQKLTNPLAWLEERRKGLQWFMTNVLLNPRWQRSTVVREFVLG
What is the function of this protein?
Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
What are the official names of this protein?
Endosomal/vacuolar adapter protein YPT35, PX domain-containing protein YPT35.
What is the protein family that this protein belongs to?
Belongs to the YPT35 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: DER_PROM5
Sequence: MTLPSIAIIGRPNVGKSTLVNRLCQSNDAIVFDKPGVTRDRTYQNASWGGKEFQVVDTGGLVFEDDSEFLPEIRTQVFLALEEASIALFVVDGNQGVTTGDLSIAKWLRNSDCKTIVAVNKCESLSLGISMASEFWKLGLGEPYPVSAIHGSGTGDLLDLVIDELPKDFDVEDKEDKVMMSIIGRPNVGKSSLLNAICGEKRAIVSDISGTTTDSIDTLIKKNSHLWKIVDTAGIRRKKNVKYGTEFFGINRAFKSIDRSDVCVLVIDAIDGVTDQDQKLAGRIEEQGRACVIVVNKWDLVEKNNSTIYQVEKELRSKLYFLHWSKMIFISALTGQRVENIFEHALNAVTQHRMRVTTSVVNEVLKEALGWKSPPTKRSGKQGRLYYGTQVKNQPPTFTLFVNDPKLFGITYRRYIEKQIRLNLGFEGSPIILLWRGKQKRDLEKETSKKNINIIQKD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CDO1_CAEEL
Sequence: MISFVQLVVQIREIFQQKLIDVDEVMKLMASYKSNANEWRRFAIFDMNKYTRNLVDVGNGKYNLMILCWGPGMASSVHDHTDAHCFVKILDGELTETKYAWPRKRHVPLDISENKTYGMNGVSYMNDELGLHRMENLSHSNGAVSLHLYIPPYSTCNAFDERTGKKTQCTVTFYSKYGKKVDYRGSKNGN
What are the official names of this protein?
Cysteine dioxygenase 1, CDO.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
Protein: UHPA_SALTY
Sequence: MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIVLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLLEKLGVSNDVELAHRMFDGW
What is the function of this protein?
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT.  Activates the transcription of the uhpT gene.  Acts by binding specifically to the uhpT promoter region.
What are the official names of this protein?
Transcriptional regulatory protein UhpA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_VIBA3
Sequence: MSTQLQSVIAVVPAAGVGSRMKADRPKQYLKINGKTILEHTIEKLLSHPQVSQIVVAISDDDPYYPELALNQNPKVVRVSGGSERADSVLSALNCIAEQQLSDWVMVHDAARPCVQLSDIDKLISGAMSHDVGAILAAPVRDTMKRGAQGQIEHTVERADLWHALTPQMFRAKPLWNALSEALQQGVSITDEASAFEWKGLSPALVAGRSDNFKITQPEDLALAEFYLSQNKE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: UPPP_MYCBP
Sequence: MSWWQVIVLAAAQGLTEFLPVSSSGHLAIVSRIFFSGDAGASFTAVSQLGTEAAVVIYFARDIVRILSAWLHGLVVKAHRNTDYRLGWYVIIGTIPICILGLFFKDDIRSGVRNLWVVVTALVVFSGVIALAEYVGRQSRHIERLTWRDAVVVGIAQTLALVPGVSRSGSTISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFHPVTEGMSATGPQLLVATLIAFVLGLTAVAWLLRFLVRHNMYWFVGYRVLVGTGMLVLLATGTVAAT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMM_GEOSW
Sequence: MEKWFNVGKIVNTHGIRGEVRVISRTDFPEERYKKGNTLYIFMEKSKEPVAVTVKSHRVHKSFDLLAFEGYDNINLVEKFKGAMLKVPESQLGELDEGEYYFHEIIGCTVVTEEGETIGTVKEILTPGANDVWVVKRDNGKEVLIPYIEDVVKNVDVETKTITIRPMEGLLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANTR6_ARATH
Sequence: MARLTLRPHNHFFSSPIYAHKQPFLSVYTIFPHHHQNPLIKSRVKCSASGTERVRESKKLPPKDPIEDPKPQLPIPEVLSTETGFEQNWPPWKNIPQRYKLIGATSLAFVICNMDKVNLSIAIIPMSHQFGWSSSVAGLVQSSFFWGYALSQLPGGWLSKIFGGRKVLEIGVFTWSFATALVPLLAGFMPGLIFSRILVGIGEGVSPSAATDLIARTIPVKERSRAVGFVFGGLSLGSVMGLLLAPPIIETFNWESVFYLFGLLGVGWFVGFQFLNEEEVSYKGNEISTSHKSENATKEELGSSLKEIPWKSFFQSPAVWAMIYTHFCGSWGHYTCLSWLPTYFSEALSLNLTEAAWVSILPPLASIVVTSLASQFADYLITNGVDTTTVRKICQTIAFVAPAICMTLSSVDIGLPPWEIVGILTAGLALSSFALSGLYCTHQDISPEYASILLGITNTVGAVPGIVGVALTGFLLDSTHSWTMSLFVPSIFFYLTGTVVWLAFASSEPQTFRKEDS
What is the function of this protein?
Inorganic phosphate and probable anion transporter.
What are the official names of this protein?
Probable anion transporter 6, chloroplastic, Phosphate transporter PHT4;5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: CCMC_SHIFL
Sequence: MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFAPADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAVFTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAGILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTLMRMRNLILLMEKRRPWVSELILKRGRK
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein C, Cytochrome c-type biogenesis protein CcmC.
What is the protein family that this protein belongs to?
Belongs to the CcmC/CycZ/HelC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADDA_ENTFA
Sequence: MSKTIPLRPANEQFTDSQWQAVFDGDENILVSASAGSGKTTVLVRRVIEKVKSGVDIDRLLIVTYTEAAAREMKERIQVALQKAMNEEQDPERRRHFSRQIALLPTANISTLHAFCLTVIRRFYYLIDIDPVFRMLTDETETLLLKEDVWDALREQFYAENQEAFYQLTANFSNDRSDDGLTNLIFSFYEFAKANPDPEAWINGLTQAYEVGDQLGESKLFQTYLKPLAVETLQRTLQRYEEMVTLTEGEEKLQKIWYLAQNEKEQTKQFLQFLERNDLESAYNLTELLSFDRYPTVRAEELKPTAEQAKQLREQNKKALNDLKKQLFTLSPDAMKQVLKEATPIVQEMAHVGKQFMEAYGAEKRLKNLVDFNDLEHYTLAILAKNQADGWHASEASVYYREKFDEVLVDEYQDINQLQESILYWLRRPLSTEGNLFMVGDVKQSIYSFRLADPTLFIEKYNQYGQGKEGKRIILAENFRSRKDVLDFTNLVFSQLMDERVGQIAYDESAALVHGFDQFSEAADYSTELLIYEKKATESVEFPELQSPELLIEDKTEGELYVTALKIRELIDQNFLIYDKKLKTDRPITYQDIVLLTPTKKNNLTILDVFKSLEIPVQVNDAQNYFQATEIRTMIALLQLIDNPYQDIPLAAVLRSPIVGLKENELVLIRLANKETSYYEAFLTFNQKMEPTMEEAVVQEKTIRFAESLEKWREQARRNQISNLLWTIYRETAYLDYVGGLPVGKQRQANLYALVDRAAAYEKTTFRGLFQFVRFIEKMQEKDKDLAEPVVLSEENAVRVMTIHASKGLEFPVVFVLDMTKEFNVSDLNERYIFEENLGVGIRYLQPEERVMYDTLPFLAIKQVRLRKLLSEEMRKLYVALTRAEQKLFLVGSYKDQAAMWKEWLKVGDVETLVLPAENRLQSKSSLMNWVGMTLVRHQKADEYQQEVVVSNVPQVKKHPANFHIQWFNEEQLRAAIQQLQLPERQAEDLAEKAQLSADKINRGLARLSFNYPFEVATRTTSYQSVSEIKRVFDDPDNKEIGKIEVREDNTIQAQPLIVNRMIEGDLSKPKFLDTVQAPSAAEIGTATHYLLQLIDLSKQPSYEEVRAVQERLVENKLILPAIAEKMNLEQIVAFFDTALGKQLIQHHQTVRREQPFSMLIEAEELIQNYPETTQDDLLIHGIIDGYIELDNQCILYDYKTDHVKGTSPQAISEIVERYRGQMNLYRRALQEATHKEVSHVYLILLNGGVIIDMQTGNVVDFIK
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: FER2_CLOPA
Sequence: MVNPKHHIFVCTSCRLNGKQQGFCYSKNSVEIVETFMEELDSRDLSSEVMVNNTGCFGICSQGPIVVVYPEGVWYGNVTADDVEEIVESHIENGEVVKRLQI
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin, 2Fe-2S, 2FeCpFd.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S Shethna-type ferredoxin family.
Protein: PSRC1_HUMAN
Sequence: MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASEETRAAKLRVSGSGEFVGLTLKFLHPSPPGPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR
What is the function of this protein?
Required for normal progression through mitosis.  Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase.  Plays a role in the regulation of mitotic spindle dynamics.  Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores.  Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles.  May participate in p53/TP53-regulated growth suppression.
What are the official names of this protein?
Proline/serine-rich coiled-coil protein 1.
What is the protein family that this protein belongs to?
Belongs to the PSRC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase.
Protein: LAPA_HAEIN
Sequence: MIKYILGIVIFIAIVLVAITIGANNDQIITFNYIVAESQFQLSSLVAILFGLGLILGWLITAFFYIKLKLKNMALARQVKRQTLQINELTTTRDKVV
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).
What are the official names of this protein?
Probable lipopolysaccharide assembly protein A.
What is the protein family that this protein belongs to?
Belongs to the LapA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_METCA
Sequence: MRIVFAGTPEFAVPTLRALIASGHPPCAVYTQPDRPAGRGRKIAPSPVKQLAIEHGLPVFQPASLKGPEERERLVALEPDLMVVVAYGLILPTPVLTVPRFGCVNIHASLLPRWRGAAPIQRAILAGDRETGVTLMRIEPRLDAGPMLGKRSCSIGDDDTTASLHDRLAGLGAEMLIELLPGLAADRLTGEIQDESQVTYAEKIEKSEARLDWQKDATSLSRRVRAFNPWPVAETTLEGTVLRIWSAQVLDPAPDAPPGSIIACTKNLDVACGRGALRILEVQPPGKRRMSAKDFLNAHALAGKRLGT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RL31_HELPS
Sequence: MKKGIHPEYIPCKVTCVTSGKEIEVLSTKPEMRIDISSFCHPFYTGSDKIADTAGRVEKFKQRYNLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PPNP_POLSJ
Sequence: MITEKIDNISVTTKANVYFDGKCVSHGITFTDGTKKSVGVILPATLTFNTGAPEIMECVAGACEYRLAGSDSWVKSAAGEKFSVPGNAKFDIRVAEGFEAYHYICHFG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: RSMJ_ACIBC
Sequence: MEKNCGSGQNKLKALRMHIYFEVDFQEQAQHYQAVLYSRGVTVDLQPIEKLNARFLRLNPDLALCVDENGLWLSANGMKMQPDWKAEIPRLKRASLKSEMIARACQLGEKPVLVDATAGLGHDSLLMAYLGAQIQLVERHPILFTLLEDSKAQAQRDPFLSQFMDRIQLLFADSASYLQQLDQEAKTVDVVYLDPMFPQRDQNQQAIKKQAQVKKQMQLLHLLLPEDGEMDLGDHLLELAKKVVKRVIVKRPRHAIFLANQEPAHQWQGDACRFDAYFQ
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOB2_CANAL
Sequence: MSFLNTIRGLGRGSKKNKKDLEPSNNAIYSHSNLSGNGLRRTQSPTKFSPSKLSSKGAQGSAAYTSSPTKRSRTGQSLQHQDSQSSLQYQQQSGSVSPSKRSSIQTTKSTTVNADPPLFLCEPYVKTALVKGSFKTIVQLPKYVDYCEWLALNIFELFNHLNRFYGVIQEYATPEAYPTMNAGPNTNYLWVNSSGQAVNLPACQYIEYVITWVTNKLNDQSVFPTKNGGAFPPNFIKDCKNISRQMFRIFAHIYHNHFDKIIHLSLEAHWNSFFAHFISFVKEFNLIDRTEMEPLLPLIENFEQQGKITQASK
What is the function of this protein?
Functions as an activator subunit for the CBK1 protein kinase.  Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network.  The RAM network is critically required for hyphal growth as well as normal vegetative growth, and for polarization of lipid rafts and the actin cytoskeleton.  It play an essential role in biofilm formation.  The RAM network also plays a role in serum- and antifungal azoles-induced activation of ergosterol biosynthesis genes, especially those involved in the late steps of ergosterol biosynthesis.
What are the official names of this protein?
CBK1 kinase activator protein MOB2.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=localizes to sites of polarized growth in both yeast and hyphal cells.
Protein: PAT_ARATH
Sequence: MASQSSVAVISSAAARGESFPDSKKPIGSVRFQQPLRLSFSYCKSGNMSSRICAMAKPNDAETLSSSVDMSLSPRVQSLKPSKTMVITDLAATLVQSGVPVIRLAAGEPDFDTPKVVAEAGINAIREGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTKISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKHIVAACSKLQGQVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRERRDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGSEAEGFGLINDSSSLALYFLDKFQVAMVPGDAFGDDSCIRISYATSLDVLQAAVEKIRKALEPLRATVSV
What is the function of this protein?
Prokaryotic-type aspartate aminotransferase.  Has also a prenate transaminase activity.  Involved in the aromatic amino acids biosynthesis pathway via the arogenate route.  Required for the transamination of prephenate into arogenate.  Required for early development of the embryo.
What are the official names of this protein?
Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, AtAAT, AtPPA-AT, Protein MATERNAL EFFECT EMBRYO ARREST 17.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBP14_BOVIN
Sequence: MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKMKNGMTVLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWVQMMRVLQQKLEAIEDDTVKETDSSSASAVTPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKESQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDLEDKKVNQQPKTGDKDSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ
What is the function of this protein?
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.  Ensures the regeneration of ubiquitin at the proteasome.  Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell.  Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.  Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1 (By similarity).  Indispensable for synaptic development and function at neuromuscular junctions (NMJs) (By similarity).  Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: DAPF_ECO81
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNTDGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKVEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_BACC1
Sequence: MKSPTGVLNIDVMEKRDKTVPIKVYHKDALKVTQPIYLDKYGRAYYYIMNSGGGYLKGDFYSININVGKDAKTYITSQSATKVYKTPNSYALQELNFYIGQNAAMEYLPDPLIMYKDAAYKQKTNIYMQNNSTLILCDSVTPGWSPNMEKFTYQYFDSLTKIYMENKLVVYDHLLLNPFKESLDQMGILNQYSHYGTFIVINENVTNDLIAALKTSFSNTNNMKIGIASTTCKGFVIRILSHNTEDMESIFFQCHRFVRENCLHEELTSYRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRM_XENLA
Sequence: MSANVQVSGQLSSGPSLPACIVLSAVSLLCFVAGFGTGAEFVRFLSFGAIFRNISGGLDGEIPLTWSEAIRNTQFQCCIGIDIGLLFLFVLQHSLMAWTAVKKNVLHVFGVLQRSIYILCTALSLQVLMRFWQPCPHGPYLWNVSSDPWSAWLPLLCALVHTISWLLIFSVLLIFDYAELMGIKQVYYFCLGMGDPLSHKSPRVARLYAHLRHPIYLELLLILWAVPCLPPDRLILAIFFTLYLSLVHRLDVQDYAYLRSQLEKKFLLFSREEASAVGGQIRKNN
What are the official names of this protein?
Nurim, Nuclear envelope membrane protein, Nuclear rim protein.
What is the protein family that this protein belongs to?
Belongs to the nurim family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: RL35_STAAE
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.