PharMolix/UniProtQA huggingface dataset:
Protein: PFP_METCA
Sequence: MAARNAFYAQSGGVTAVINASACGVLETARQYPDRIGTVYAGRNGIVGALTEDLIDTGQESAEAIAALRHTPSGAFGSCRYKLKGLEENRAQYERLIEVFRAHDIGYFFYNGGGDSADTCLKVSQLSEKLGYPLQAVHIPKTVDNDLPITDCCPGFGSVAKYIAVSVREASFDVRSMAATSTCIFVLEVMGRHAGWIAAAGGLASDERHELALVILFPEQVFDPERFLRAVDEKVRSHGYCSVVVSEGIRGADGRFVAESGSRDVFGHARLGGVAPVIADLIKERLGYKYHWAVADYLQRAARHIASRTDVEQAYAVGKAGVEMALKGLSAVMPAIVRTSDSPYRWEITAASLAEVANVEKKMPLEFISADGFGITEACRRYLRPLIEGEDYPPYAGGLPDYVTLCNVAVPKKLAASFSV
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, 6-phosphofructokinase, pyrophosphate dependent, PPi-dependent phosphofructokinase, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_RHIEC
Sequence: MAKTSAVEKNKRRRTTVANQAAKRAALKAIIMNQALPIEERFKASIKLASLPRDGSKTRIRNRCEVSGRPRAYYRKLRMSRIALRELGNLGKVPGIVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL1_PSEA7
Sequence: MAKLTKRQKAIAEKVVAGKQYSFEEAAKLLAELSTIKFKESVDVAVNLGVDPRKSDQVVRGATVLPNGTGKSVRVAVFTQGPAAEAALAAGADKVGMDELAAEMKGGDLNYDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVRFRTDKNGIIHSSVGKVDFEPAKLQQNVEALLADLKRLKPSSSKGVYVKRVTLSTTMGPGLQIDLASLEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GLHA_NIPNI
Sequence: MGCYGKYAAVTLTILSVFLHLLHAFPDGEFLMQGCPECKLGENRFFSKPGAPIYQCTGCCFSRAYPTPMRSKKTMLVPKNITSEATCCVAKAFTKITLKDNVKIENHTDCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of heterodimeric glycoprotein hormones.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1423_STRZP
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SPP_1423.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: SAR1_CANAL
Sequence: MWIFDWFQDILSSLGLWNKHAKLLFLGLDNAGKTTLLHMLKNDRLATLQPTLHPTSEELAIGSVRFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAADTERFAESKAELESLFRIEELSQVPFVILGNKIDVPTAVGEMELKNALGLYNTTGKDTGKLPEGTRPIEVFMVSVVMRSGYGEAFKWLSQYI
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BKTB_CUPNH
Sequence: MTREVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSRAPYLAPAARWGARMGDAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGALITVKALHELNRVQGRYALVTMCIGGGQGIAAIFERI
What is the function of this protein?
Required for efficient production of poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).  Catalyzes the condensation of acetyl-CoA and propionyl-CoA to form beta-ketovaleryl-CoA, and the condensation of two acetyl-CoA molecules to form acetoacetyl-CoA.
What are the official names of this protein?
Beta-ketothiolase BktB, Acetyl-CoA acetyltransferase, Acetyl-CoA acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: SYE_METMP
Sequence: MKDTVMTYLLENSIKFKGKPNPKAAMGKILGENPDLRSKVKEVNQVISEVLKEIETMSLEEQQAKLDELAPEGLGQKTERKRKEIELKNVKGNVVMRFAPNPSGPLHIGHARASVLNDFFSKKYNGKLVLRLEDTDAKRVLPEAYEMIQEDLKWLGVKVDEVIVQSERLETYYEYGRKLIEMGHAYVCDCDADEFRTLREQGLPCKCRDTTPEENIALWEKMLAGELDNVAVRLKTDIAHKNPSIRDFPIFRIERTPHPKNGTKYHVYPLMNLSVTVDDHLLGMTHVLRGKDHIVNTEKQEYIYNYFGWEIPEYVHYGILKIEGPVLSTSKMHAGILSGEYSGWDDARLGTLRALRKRGIRPEALYKLMVEIGIKQADVRFAWENLYAANKDIIDKDARRFFFVESPKKLVISGAENRKIDLRMHPDRSELGNRELLFDGEIYVSDDLEAGKMYRLMELFNIVVEKVENDIIYAKYDSDDFKVAKTNKASIIHWIPVKDSIPVTVIDENAEKIEGFAEKDFAVVKEDDFVQFERFGFVRIDEKLDNKYTCYLTHK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEB_CALSA
Sequence: MLKLKKAIKRITLCVAVVFLLQILFLFSGYNNSDVKAATTFNYGEALQKAIMFYEFQMSGKLPSWI
What are the official names of this protein?
Uncharacterized protein in celB 3'region.
Protein: NUSB_BRADU
Sequence: MADNNKKPAGLTEKKANRRGAARLAAVQALYQMDIAGAGINDIFAEFESHWLGNEVEGDTYLPAEAAFFRDVVSGVVRDQKKLDPLIDEALSKGWPLKRIEAILRAVLRAGAYELQHRKDVPGRVVVSEYVDVANAFVDREETGMVNAVLDQIGRQFRGDEFGRG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PYRH_AQUAE
Sequence: MEEKPKYKRILLKLSGEAFAGEQGYGIDPAFLEYISHEIKNVYDLGVQVAIVIGGGNIFRGFQGKEIGVDRATADYMGMLATVINALALQSALENHVNIPTRVLSAIEMRQVAEPYIRRRAIRHLEKGRIVIFAGGTGNPFFSTDTAAALRAAEIGAEVLIKATKVGGIYDKDPEKYPDAVLIKEISYLEVINMGLKVMDHTALTLCKENEIPIIVLNVKEKGNLRRAVLGEEVGSVVRG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_SALA4
Sequence: MAKILVLYYSMYGHIETMAHAVAEGAKKVDGAEVIIKRVPETMPPEIFAKAGGKTQNAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLGSVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: KV3AD_MOUSE
Sequence: DIVLTQSPASLAVSLGQRATISCKASQSVDYDGDSYMNWYQQKPGQPPKLLIYAASNLESGIPARFSGSGSGTDFTLNIHPVEEEDAATYYCQQSNEDPFTFGSGTKLEIK
What are the official names of this protein?
Ig kappa chain V-III region PC 7043.
Protein: CYB_SCHOT
Sequence: MKFLKSNPFLALANNYMIDAPEPSNISYFWNFGSLLACVLVVQIVTGILLACFYVASMDLAFASVERIGRDVNYGFLLRALHANGASFFFIFLYLHIGRGLYYGSYRAPRTMTWNIGVIIFLLTIITAFLGYCLPANQMSFWGATVITNLLSAVPFIGDDLVQLLWGGFSVSNPTLNRFFSLHYLMPFVIAALSIMHLIALHTNGSSNPLGVTANMDRLPMNPYFLIKDLITIFIFLLAINYMVFYNPYGFMEPDCALPADPLKTPMSIVPEWYLLPYYAILRAIPNFQLGVVAMLLSILVLLLLPLLDFSAIRGNQFNPMGKFFFWCFVADFCILAWIGGSHPENVFITIGAYATAFYFIYFFILIPVYTILGNTLIDLGLPRSNK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISN1_YEAST
Sequence: MSSRYRVEYHLKSHRKDEFIDWVKGLLASPFVLHAVSHEGDYNDDLATTQRVRSQYADIFKDIEGLIKDKIEFDSRNMSQDEIEDGASSQSLNILGQSRLNLLVPSIGTFFTELPLEQAFLWEDSQRAISARRMVAPSFNDIRHILNTAQIFHFKKQENLHNGKVLRLVTFDGDVTLYEDGGSLVYTNPVIPYILKLLRCGINVGIVTAAGYDEAGTYENRLKGLIVALHDSTDIPVSQKQNLTIMGGESSYLFRYYEDPEEDNFGFRQIDKEEWLLPRMKAWSLEDVEKTLDFAERTLNRLRKRLNLPSEISIIRKVRAVGIVPGERYDEASKRQVPVKLDREQLEEIVLTLQNTLESFAPSRRIQFSCFDGGSDVWCDIGGKDLGVRSLQQFYNPESPIQPSETLHVGDQFAPVGSANDFKARLAGCTLWIASPQETVNYLHRLLETD
What is the function of this protein?
IMP-specific 5'-nucleotidase involved in IMP (inosine 5'-phosphate) degradation.
What are the official names of this protein?
IMP-specific 5'-nucleotidase 1.
What is the protein family that this protein belongs to?
Belongs to the ISN1 family.
Protein: NTPP_RICRS
Sequence: MKQNRKNLPIILASSSPARIELLNRIKIIPSQIIPADIDETPNLRELPAPLAIRLAYEKAIKIASQIEESAIIIAADTVAAVGRRILPKATTYEEVKNCIKMLSGRRHRVYTGLCIIKKENDQLTVRQKIVQTIVKFKKLSDEEINFYCSLDEGIDKAGGCKISGYAEAFISFISGSYSNVMGLPLFETVNALTSLGFRCSSIMPAKMNYCHSAT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CAMC1
Sequence: MNTFGKKLTLTSFGESHGVAIGGVIDGLPAGLKIDADFIQSELDKRRPGQSSFTTARDEADKIEIFSGVFDGMSTGAPIGFAIFNNNQKSNDYENLREIFRPGHADLTYFKKYGIRDHRGGGRASARETAVRVAGGAFAQLLLNELKIEVLSGVLGIGKVVSDKIDFDFAQNSQIYALGNEEAMKEAVNKARSEHDSVGAVVLSVARGVPAGLGEPLYDRLDSALAAALMGINGVKAVEIGAGVNVSSMLGSANNDEMDELGFLSNNAGGILGGISSGAEIVLKSHFKPTPSIFKEQKTLNLAGEAVDFELRGRHDPCIGIRGSVVATAMIRLVLADMLLLNASTKLENLKKIYG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GLUQ_PECAS
Sequence: MSVTDCFTQINSFTQINHFTETHRYVGRFAPSPSGDLHFGSLIAALGSYLQARSQQGRWLVRIEDIDPPREIPGAASRILAQLEHYGLYWDGDVVYQSQHHARYREILQQLQQQGMSYYCTCTRSRIQQLGGRYDGYCRTRNLSADNAAQRLRQTTPVFHFHDKLRGNLYADKTLAQEDFIIHRRDGLFAYNLAVVIDDNDQGITEIVRGADLIEPTVRQISLYQQLDYAIPTYVHLPLVLNTEGNKLSKQNHAPALPDSDPRPVLLAALQFLNQPLPENGQEMTLSALLAWSVAHWSLNIVPLQAAINTSTFTSAFSKGPW
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: RL36_MYCPN
Sequence: MKVRASVKPICKDCKIIKRHQIVRVICKTQKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PANC_PSEAE
Sequence: MNTVKTVRELRAAVARARSEGKRIGFVPTMGNLHAGHAALVKKAGERADFVVVSIFVNPLQFGPSEDLDTYPRTLAADQERLLEAGCHLLFTPTVEEMYPDGMDGQTRIHVPGVSEGLCGASRPGHFEGVATVVSKLLNMVQPDLALFGEKDFQQLAVIRKLVRDLNLPVQIFGEPTVRAADGLALSSRNGYLDEQQRAAAPAIYRTLRQLGERIRAGAEDFPALLADARQALEQAGLRPDYLEIREPISLRPGVPGDRQLVILAAAYLGSTRLIDNLSVHLD
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORA_ZOBGA
Sequence: MKKVLLFLIFLVSANLSAQLPSPTNGKKWEKVEQLSDEFNGNSIDTNKWYDYHPFWEGRAPSNFKKGNAFVSDGFLNLRSTLRKEPSSVQDPFKDIWVDAAAAVSKTKAQPGYYYEARFKASSLSMTSSFWFRVGQFSEIDVIEHIGNPSKENRQDDLPYQYHVNTHYYGKHAGLQPLGTEYKMPGRGRDNFYTYGFWWKSPNELLFYFNGKQVMRIVPRVPLDEELRMIFDTEVFPFATAGVANIGLPKPENLRDNSKNTMKVDWVRVYKLVDGTAAEDSSDAPIGSYISLKKTQGDGKFVTGEKDGSQLVARGSTVQSWEKFKVEKHPKGGITLKANSNGKYVQVQGSDINKPVRAAGDFQGDWEQFEWKSKGNGLVALKNVLTGKWLQAPWTENNAIIRPKGPVDNGWETFAWKKETSPTASTALSAQLETKTVDGIRVYPSPASETLTIEGVEGENGLRVFDSTGNPVLKKEGILGRKERLNVSGLIKGNYLLRTGSGEQTWFQKN
What is the function of this protein?
Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6-sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6-sulfate-(1->3)-beta-D-galactose.  Some longer oligosaccharides of even number of residues are also observed.  Inactive on the non-sulfated agarose portion of the porphyran backbone.  Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.
What are the official names of this protein?
Beta-porphyranase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PUR9_STRZP
Sequence: MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVDTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNLYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAANGETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHMNPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SYM_PSEPG
Sequence: MSEPRQILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKMRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSSDFADFLVDFDNFHSTHSEENRELSSLIYTRLREAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCAAEDQYGDNCEKCGATYAPTELKNPKSAISGATPVLRDSQHFFFKLPDFQAMLQQWTRSGTLQDAVANKLAEWLDSGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWNEGSKAELYHFIGKDIVNFHALFWPAMLEGAGFRKPTAVNVHGYLTVNGAKMSKSRGTFIKARTYLDHLQPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNEGVMVSGDAAPELTEAFLTAAPSIAEAYEARDFGRAMREIMALADRANAWIADKAPWSLAKQEGKQDEVQAICAQGINLFRQLVIFLKPVLPVLAADAEAFLNVAPLTWSDHLSRLENHKLNPFKALMSRIEPAKVEAMVAASKEDLLATQAKAPAGNGELTKDPLSAEIEFDTFAAVDLRVALIVKAEAVAGADKLLQLTLDIGDERRNVFSGIKSAYPDPSKLEGRLTMMVANLKPRKMRFGVSEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_LACPL
Sequence: MTKTVEMVITGAQVLNVYTREFEATSLWIDHGRIISNLRDEPYIAAQHVDATGQWIVPGMIDAHVHMESSMVAPSELGKVLLQHGVTTIATDPHELANVAGIAGIQYLIDDARQTPLDVCFMLPSSVPCVPFDDNGATLHAADLRPLYQQSEVRGLAEVMDYGAVARGDTDTLAKISDAYAYGYHADGHAAGLNAHQLNVMRNAGLDTDHECMTVAEAQDRVRAGMAVFLREGTVERDVLPTIGAVTEANASRFAFCTDDKMISDLLTEGSIDYNVRLAMQSGMRPELAYTLASLNGAMAHRLSDRGSLSAGQLADLVVLDDLEHVRIARTMKRGQWILPSTTKPLPFTATRVQHHAQLADFQLPLATGLANVIGVQPNHIETDHLTLPIDATQNFEADCQRDILKMVVIERHHNTGKVGVGLVHGFALKQGAIAGTVAHDAHNIVAVGTSDAAILRAVAQITQDNGGIAVVDNEQVLATMPLAIGGLLSAASYQKVAEQLAELKRAYEVISERPLSFDPFITLSFLTLPVIPTLKLTARGLFDYATFDFIPVAIQDNQRQTV
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: SPEE_THEP3
Sequence: MELWFTENQDENLRFSLKVKETLVVEKTPYQHLAILDTYQFGRVLTLDGILQTTEKDEFVYHEMIVHVPLFTHKNPKSVLIVGGGDGGSVREVLKHPSVERVVLAEIDEAVVRNSKKYLPTISQALDDPRVEIMIGDGIKYVNEHKNEFDVVIVDSTDPIGPAVGLFTSDFYKAVYECLKEDGIIVAQTESPFIYGKLINKLSKMFKEIYPITKAYIATIPTYPGSLWTFTMGSKKYDPEEVDINSIPRIDTKYYTPEIHKAAFVLPKFVKDIFDEV
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PYRCJ
Sequence: MVRRFKRATKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWSLVMKYGESGTGWPFYGKHGFKQPETISVEWRPINVGRLAELVKELRERGEVREEEGRLVVDLLKLGYNKLLGGGHMDVPLVVYTPVASKAAVEKIAKAGGEVRIVSLVHR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: AGO2_XENLA
Sequence: MYSGAGPVLVPPTTTPPLPMPAYTFKPPPRPDFGTSGRTIKLQANVFEMDIPKIEIYHYDIDIKPEKCPRRVNREIVEHMVQHFKAQIFGDRKPVFDGRKNLYTAMPLPIARDKQVELEVTLPGEGKDRIFKVAIKWMACVSLQALHDALSGRLPNVPFETVQALDVVMRHLPSMRYTPVGRSFFTASEGCANPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPFVREFGIMVKDDMTDVTGRVLQPPSILYGGRSKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKTFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLSAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDRNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQVHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC).  The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA).  These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing.  The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target.  Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2.  Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity.  The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
What are the official names of this protein?
Protein argonaute-2, Argonaute2, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2, Protein slicer.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: SKP1_SCHPO
Sequence: MSKIKLISSDNEEFVVDQLIAERSMLIKNMLEDVGEINVPIPLPNVSSNVLRKVLEWCEHHKNDLYSGTEEESDIRLKKSTDIDEWDRKFMAVDQEMLFEIVLASNYLDIKPLLDTGCKTVANMIRGKSPEDIRKTFNIPNDFTPEEEEQIRKENEWAEDR
What is the function of this protein?
Required for cig2 degradation in the G2 and M phases of the cell cycle.  Together with pof6, essential for septum processing and cell separation.  Involved in mitotic progression, essential for the execution of anaphase B; required for coordinated structural alterations of mitotic spindles and segregation of nuclear membrane structures at anaphase.  Involved in the DNA damage checkpoint pathway and maintenance of genome integrity.  Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.
What are the official names of this protein?
Suppressor of kinetochore protein 1, P19/Skp1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MHR1_ASHGO
Sequence: MSKTVGASRFRPAGWLQRAGYAPQVFVFRNLESGQVIYSQLPTFTERQINKNFYRPNWENRKPSTRPDIWKCMAVVDLASHEESVRLYQNLCRLRYLREVPQRKAAEQLRKRNEFGHIWYSAQYRPTYTQEAVADLRECLLRARGGATVHWEDPWRMGDRAKHWAALPAVQHQFLPRMANVAREESAILKQLGERAKRAFAAPAPPAPAPQSL
What is the function of this protein?
Transcription factor involved in regulation of RNA polymerase II-dependent transcription.  Also involved in regulation of mitochondrial DNA recombination, maintenance and repair, and generation of homoplasmic cells (By similarity).
What are the official names of this protein?
Mitochondrial homologous recombination protein 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL67 family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.