PharMolix/UniProtQA huggingface dataset:
Protein: SEC11_LEPMJ
Sequence: MLGVSGMQPRQLAAQILNFALVLSTAFMMWKGLSVVSDSSSPIVVVLSGSMEPAFQRGDLLFLWNRGLDTQVGEIVVYNVKGKDIPIVHRVVRRYGGGKTPLRLLTKGDNNIADDTELYATSQSFLTRKEDVVGSVVGFIPFVGYVTILLSENPWMKQVMLGLMGVMVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NDUB8_MOUSE
Sequence: MAAARAAALGVRWLQRTTRGVVPLEARRAFHMTKDMLPGSYPRTPEERAAAAKKYNMRVEDYEPYPDDGMGYGDYPMLPNRSQHERDPWYQWDHSELRMNWGEPIHWDLDMYIRNRVDTSPTPVSWDVMCKHLFGFVAFMVFMFWVGHVFPSYQPVGPKQYPYNNLYLERGGDPTKEPEPVVHYDI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Complex I-ASHI, CI-ASHI, NADH-ubiquinone oxidoreductase ASHI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: CXA1_CHLAE
Sequence: MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHTTSGALSPTKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
What is the function of this protein?
Gap junction protein that acts as a regulator of bladder capacity.  A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.  Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.  May play a role in cell growth inhibition through the regulation of NOV expression and localization.  Plays an essential role in gap junction communication in the ventricles (By similarity).
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.
Protein: MCM_SACS2
Sequence: MEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESGKIDIDTIMTGKPKSAREKMMKIIEIIDSLAVSSECAKVKDILKEAQQVGIEKSNIEKLLTDMRKSGIIYEAKPECYKKV
What is the function of this protein?
Presumptive replicative helicase.  Has ATPase and DNA helicase activities.  The latter preferentially melts 5'-tailed oligonucleotides and is stimulated by the SSB protein (single-stranded DNA binding protein).  The active ATPase sites in the MCM ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The helicase function is proposed to use a partially sequential mode of ATP hydrolysis; the complex appears to tolerate multiple catalytically inactive subunits.
What are the official names of this protein?
Minichromosome maintenance protein MCM.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
Protein: RS18_BACC7
Sequence: MAGRKGGRAKRRKVCFFTANGITRIDYKDVDLLKRFVSERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVGE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GGNB2_DROME
Sequence: MARLTKVYNTDDDDSGYVGRRNLPLVAGDKLMMLMDLNSKGLVIDSPLIRGRELEEFSRKFKLLTEAERRQSLEIDSASFMEVLNQCVQCVGCRRRVERLFHQLTETGHRTLDPLELRPTATLGIVEEKLKTPQALGTLLYRHHEVLNNLLDNKLRNKTRCVLHSLDAFRAKPFSETWREVWSAMKSNCRNELTIIETKELHDVLENYLKKHKFCSGCRTKIERAYKILIGEISSKEKGYAAQLYAHIRKCVPDQHIHVTTNKIEFLDALIKRAEPEVNGSYSKLRERHAKTLEIAQEEVLTCVGMIMYERLRRIYVSLREEERACQVLAAVGVHALCRSFDTFVEQKQGISNLELLYQEISRAERAKQIKREQKKLKKKKKKDEKKNLLHRQCDDTEANESDEEEEELRNEELDLEEESQMQHEELSDPGADDGIVIEAARSPEPEPELTSKPTKSKPKKQSKKKKQKKAAFTKMGNQKQMQATARVQPLDADHDQLDVASCISSSIAKTVGDKCEECLASMPNCPCEQDVRDSGYGSDPPSHAGSRTSSAISSPEGSEVSCSDGLCNHDVHDEDSDDLLFYSHQSQLDHKFSLLQMWDDFDEYDDKDEETYYIPQEVVMAFKCHREQVQRKREELRAKLRANFERLCVQHGVQTQVQKSKRTTSALVGQ
What are the official names of this protein?
Gametogenetin-binding protein 2-like.
Protein: EFP_BACSU
Sequence: MISVNDFRTGLTIEVDGGIWRVVDFQHVKPGKGAAFVRSKLRNLRTGAIQEKTFRAGEKVAKAQIETKTMQYLYANGDQHVFMDTSSYEQLELSATQIEEELKYLLENMSVHIMMYQDETLGIELPNTVELKVVETEPGIKGDTASGGTKPAKTETGLVVNVPFFVNEGDTLVVNTSDGSYVSRA
What is the function of this protein?
Plays a role in sporulation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAY_ECOUT
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: DPO4_SHEB9
Sequence: MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYKEVSLQIREIFSRYTPLIEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPDFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRERKSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVPEIPNAQTQLDLAL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK27_THAPS
Sequence: MAHKKGAGSTKNGRDSNAKRLGVKRFGGETVKAGSILIRQRGMKFKPGVNVGYGKDFTLFALIDGTVKFDYKDAQHKRVNIITQ
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YNDM_BACSU
Sequence: MTIMNGFELHYLSFVYAQEFSSKNNNLGGQMKHIIALASKIAFTLALLYVILDRVYHASFLSVMFIALFLGFVSYLSGDMLVLPRTNNITASLADFGLSFVILWVFVLTQTRNDFSPFGAALLSAACLTVFEYFFHRYLLKNVLDENFRNELSARDNTLQYQTEAADELFPETKEKHKE
What are the official names of this protein?
Uncharacterized membrane protein YndM.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMYM_BACLI
Sequence: MIELAAIHHQPFNSDAYSYNGRTLHIKIRTKKDDAEHVAWFGAILTNTPAHMESERAYVAKIGRNKQPMITGLPKCGLHSGSAIRIYLTALMIETLFTEAMVHVRFRYRQTHVLNFRLFMRQTRLMHRLGQINRLVSNFSGAFRAGGKICSGKPLPWGRKDPEAHDFFGGHLQGIMTSWTIWKTWGEAGIYLTPIFAAPSNHKYDTLDYCSIDPHFGDEELFRTVVSRIHERGMKIMLDAVFNHIGTSQEWQDVVKNGETSRYKDWFIFILSLLKKAAMIHLRLVPRCRSSIAGTRKFRLICLILRCTGSANLISTAGVWMWQMKLIMRFGRNSGKPSPEKPDIFILGEIWHQADPWLRGDEFHIGHELPVHRTDDSLFFRRIDFSSQIASRINSQKMSGMKQVKEVMLNLLDSHERILTRCGGDQRKGARLFWHSCLLRQGRIYYPRKSGFTAAMIHCAGSAWFGKRKNRIKRCLAFMKPLIALRKQENDVLTYGALEWKLVDDQNDFVSFSRTHEGKELIYFFHQGREVRRVRLRDLKIASDKRIYDAWTEEALHDDDVVDIQPGDFSFLGRSKFC
What is the function of this protein?
Converts starch into maltose.  In contrary to other maltogenic alpha-amylases BlmA cannot hydrolyze 1,4-alpha-glucosidic linkage next to 1,6-alpha-glucosidic linkages.
What are the official names of this protein?
Maltogenic alpha-amylase, Glucan 1,4-alpha-maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: CUTA_SALHS
Sequence: MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGI1_KOMPG
Sequence: MGRRKSQAAAERNLEPIKISTDSIKKRPRRDSNEPPFKKFDDLEMFETYLKGESWDNDFDFLHARLDYYPPFIRNEIHDDPEKIKPTMNNKSKKFVRNLHHHVDKHLLKQINDMVGIEYKFKREEEKLPDGRLIWRYKDESDHGFEGLDRKWTVEVDVECSPNDPTVVVDMRSIPID
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYY_STRP3
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIESQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRIQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRR3_MOUSE
Sequence: MPKRKKQDQPPPLPQQQQHLALSERDEPGDEEDERPMGPPSLLGPPPMANGKPGDPKSAFHRGPPGSRGRMIPPLLSLPPPPRGRGYIRGGLGPRSSPYGRGWWGINAEPPFPGPGHGGPSRESFYKEARNPRRLRSWSLVKNTYPPKDSPQMMEDKSDRPVCRHFSKKGHCRYEDHCAFYHPGVNGPPL
What are the official names of this protein?
Proline-rich protein 3, MHC class I region proline-rich protein CAT56.
Protein: RPOZ_LIMF3
Sequence: MILFPSVDKLLERVDSRYSLIMLASKRAHEIDKYRIDKWRAAHPDKAGETVSLEGDKPLLLDHYDSNKSVGMALEEIEAGLVTIDPDQHEDLQD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y755_CHLPN
Sequence: MLLVRKWLHTCFKYWIYFLPVVTLLLPLVCYPFLSISQKIYGYFVFTTISSLGWFFALRRRENQLKTAAVQLLQTKIRKLTENNEGLRQIRESLKEHQQESAQLQIQSQKLKNSLFHLQGLLVKTKGEGQKLETLLLHRTEENRCLKMQVDSLIQECGEKTEEVQTLNRELAETLAYQQALNDEYQATFSEQRNMLDKRQIYIGKLENKVQDLMYEIRNLLQLESDIAENIPSQESNAVTGNISLQLSSELKKIAFKAENIEAASSLTASRYLHTDTSVHNYSLECRQLFDSLREENLGMLFVYARQSQRAVFANALFKTWTGYCAEDFLKFGSDIVISGGKQWMEDLHSSREECSGRLVIKTKSRGHLPFRYCLMALNKGPLCYHVLGVLYPLHKEVLQS
What are the official names of this protein?
UPF0242 protein CPn_0755/CP_1117/CPj0755/CpB0783.
What is the protein family that this protein belongs to?
Belongs to the UPF0242 family.
Protein: VU9_HHV6Z
Sequence: MAVRKLWKTVVQLFSKSKSEECNTEAGTMEVSCLKYGVQGLNADCSYVKSQCIKLSECECLYTFASDVCKEDFHNSEEMKVFVVQHSQEIVGGTDFSVHAEESV
What are the official names of this protein?
Protein U9.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HYAS3_CHICK
Sequence: MPVSLSTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLFIQSLFAFLEHRRMRAERQPVRLGRSVALCIAAYQEDPDYLKKCLLSVKRIAFPDLKVVMVVDGNGPDDTYMLDIFHDVMGSERAGSYVWRSNFHARGEGETEAGLQEGLAHVQALVRSTTYSCILQKWGGKREVMYTAFRALGDSVDYIQVCDSDTVLDPACTAEMLRILEADPRVGGVGGDVQVWRRGGDGTHGGTALALVALTPSPPQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNALLQQFLEDWYHQTFLGTKCSFGDDRHLTNRVLSLGYQTKYTARSRCLTETPTRYLRWLNQQTRWSKSYFREWLYNALWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGSAEMIFVSLYALLYMSSLLPAKMFAIATINKSGWGTSGRRTIVVNFVGLLPVSVWAAVLLGGLAYTAYSQDLLSDTEVAFLISGAVLYACYWVALLTLYLAMVARRCGKRKEQCGLVFAEV
What is the function of this protein?
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer.  Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity).  This is one of three isoenzymes responsible for cellular hyaluronan synthesis.
What are the official names of this protein?
Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, CHAS3, HA synthase 3.
What is the protein family that this protein belongs to?
Belongs to the NodC/HAS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane. Golgi apparatus, trans-Golgi network membrane. Cytoplasmic vesicle. Note=Travels through endoplasmic reticulum (ER), Golgi, plasma membrane, and endocytic vesicles (By similarity). Actives only when present in plasma membrane (By similarity). O-GlcNAcylation controls its membrane localization. A rapid recycling of HAS3 between plasma membrane and endosomes is controlled by the cytosolic levels of UDP-GlcUA and UDP-GlcNAc (By similarity).
Protein: G6PD_THEMA
Sequence: MKCSLGLEKCPDDTLRCFPKIEQPFGIVIFGASGDLTKRKLIPALNRLFEAGILPERFFVLGAARTKMDDKKFRSRFDANPDFLEHCSYISVDYQDPESFKQLKNTIETLIKRIDSSNLVFYLAVPPDLYIPILENLSKTGLNEKPARVVIEKPFGKDLESARRLEDTLQKYFQEDQIFRIDHYLGKETVQNILVFRFANFIFEEIWNNKFVDHVQITMAEDIGVEHRAGYFENVGLLRDIFQNHMLQILALIAMEPPSSFNGENFRNERVKLLRSIRPFPVEELESWIVRGQYGRGVVNGKEVPAYREEPGVAKDSNVETFVAMKLFIDNWRWSGVPFYLRSGKRLPKKITEVAVVFKKIPHSIFAGVPSDELEPNTIVFTLQPNEGISLEFQVKRPCPGMFPQLLSMDFRYEDYFGVKLPDAYERLLLDVILGDPTLFMRRDDLEVSWELLDPVLKAWENDPVRFSPYVYPAGTWGPREADLLIERDGRKWRKL
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: DBP8_USTMA
Sequence: MPQVAASSSNVGPSSAAASSASHVQEVAKSASDPPKHTSFSSIGISPMLIRSLASLQIKVPTPIQSLTIPSVLEGRDLVGGAQTGSGKTLCFALPILNKLIKDMVGGFAVVLTPTRELGVQLHEQFVAVGEGARMGLRCALVLGGMDMMKQASELANLRPHVIVATPGRLVDHLRSGGGEEWGLRRCKFLVLDEADRLLTDTFKPELEYLYSVLPSAKTLQTLLFTATLTEQVVEFANAKRPEGKPAPMVCKIEMDTKTPETLEQRYVFVPSHVREPYLYHILRHPPIKPSSERVRKLNAKHQADRERKEENQRKSGKRRRTHHASDSDLDQDDDAALFLPATIIFTARCKTAATLSGMLAELGIPNVSLHSHLRQSERSENLQTFRAQRVPVLIATDVGSRGLDIPDVELVINWDLPSAWQDYVHRVGRTARNGKRGFAISFITERDIDVIHSIEDKINTKLTQLEGLEDEDKILEKLNAVATAKRVATMALHDSQFGERQQRNQHKQLARLKAEKRASKKAKSAGHDQQ
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PURO_METJA
Sequence: MYIGRFLVVGKTKEGKPFAAYRVSSRSFPNREAKKMDDNTVAIIPKDLNEMFKNPYITYNCIKVIDKTIVVSNGTHTDFIAEKLHFGKRDALAYVLAVMDYEKDDYKTPRIAAILDENECYMGYVAHDDIRVKKVELKDGKGYYLGVYNACKIDENQIIDIKGETAEEIADYILNYEEFEHPVACAVAVIDKDGIKIATKGK
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: THIM_ECO7I
Sequence: MQVDLLSSAQSAHALHLFHKHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMSAAVEQATRSQTPWTLDPVAVGALDYRRRFCVELLSHKPTAIRGNASEIMALAGVANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRIVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SODF_ACIAM
Sequence: MSSLTYLKKYELPPLPYNLDALEPYISKEIIDVHYNGHHRGYVNGANSFVDRVNKILKGEISSGQYDIQGLLRGLVFNINGHKLHSLYWQNMAPAGKGGGKPGGVIGDLIEKQYGSFEKFKALFTEAANSLPGTGWTVLYYEVENGNLQIMTFENHFQNHIAELPILLILDEFEHAYYLQYKNKRADYVNNWWNLVNWDFADKKLQQYMKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: UBP50_MACFA
Sequence: MTSQRSLPADDFGIYYVLAECTDYYDTLPVKEADGSQPCSQGVTGLRNLGNTCYMNAILQCLCSISPLVEYFLSGKYITALQNDCSEVATAFAYLMTDMWLGDSDCVSPEIFRSALGNLYPAFTKKTQQDAQEFLIYVLNELHEALKKYHYPRRRSHEKGSAQRCCRKWITTETSVITQLFEGQLNYSIVCLKCEKCTYKNEVFTVLSLPIPSEYECSLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRAGISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICPIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNSFTQAWYSFDDTRVSEIPDTSVQNATAYLLFYSCQPFSIPIQKH
What is the function of this protein?
May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Putative ubiquitin carboxyl-terminal hydrolase 50, Deubiquitinating enzyme 50, Ubiquitin thioesterase 50, Ubiquitin-specific-processing protease 50.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: SAT5_STACB
Sequence: MSTMAKSPEANNLHQDVIAQFPILNGYTHTVGAFSQPLNVSRLFIIDEIQTAYDELRVQIPWLAHQVVVVDAGPGKSGYITTAPWPSSAPPNDVTYEEKDDAFPSLNTLIKSGGSFLATKDLVGYPGLPEPHGLHPTPVATIRLVFITGGVLVVLSTHHNIVDGIGLMQMWDYLDILMGGGAISRQDARSANADRARVLPLIAPGEPVKDYSHLIRPNPWPLPPPPKTEWRLFKMHPWALAEIRSRARDGTDQRASARPASSDDALTAFCWQRVSAMRLASGRVTGDQVSKFGRAVNGRSAMGLDSSYLFHMMLHTETRLPIEQIARSTLAELSTQLRKDLDAARTEWSVRSYATFLAGVADKTRLLYGGITNPQTDLGGTSTMHWASRRPIRLGLLGDCHLIRKPEGMPLPGCLYFMPSGGTSGVVQLLLCLPKEELDALQEDAEWKHYTESGGRRVDGPRL
What is the function of this protein?
O-acetyltransferase; part of the satratoxin SC1 cluster involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings (PubMed:25015739).  Satratoxins are suggested to be made by products of multiple gene clusters (SC1, SC2 and SC3) that encode 21 proteins in all, including polyketide synthases, acetyltransferases, and other enzymes expected to modify the trichothecene skeleton (PubMed:25015739).  SC1 encodes 10 proteins, SAT1 to SAT10 (PubMed:25015739).  The largest are SAT8, which encodes a putative polyketide synthase (PKS) with a conventional non-reducing architecture, and SAT10, a putative protein containing four ankyrin repeats and thus may be involved in protein scaffolding (PubMed:25015739).  The putative short-chain reductase SAT3 may assist the PKS in some capacity (PubMed:25015739).  SAT6 contains a secretory lipase domain and acts probably as a trichothecene esterase (PubMed:25015739).  SAT5 encodes a putative acetyltransferase, and so, with SAT6, may affect endogenous protection from toxicity (PubMed:25015739).  The probable transcription factor SAT9 may regulate the expression of the SC1 cluster (PubMed:25015739).  SC2 encodes proteins SAT11 to SAT16, the largest of which encodes the putative reducing PKS SAT13 (PubMed:25015739).  SAT11 is a cytochrome P450 monooxygenase, while SAT14 and SAT16 are probable acetyltransferases (PubMed:25015739).  The SC2 cluster may be regulated by the transcription factor SAT15 (PubMed:25015739).  SC3 is a small cluster that encodes 5 proteins, SAT17 to SAT21 (PubMed:25015739).  SAT21 is a putative MFS-type transporter which may have a role in exporting secondary metabolites (PubMed:25015739).  The four other proteins putatively encoded in SC3 include the taurine hydroxylase-like protein SAT17, the O-methyltransferase SAT18, the acetyltransferase SAT19, and the Cys6-type zinc finger SAT20, the latter being probably involved in regulation of SC3 expression (PubMed:25015739).
What are the official names of this protein?
O-acetyltransferase SAT5, Satratoxin biosynthesis SC1 cluster protein 5.
What is the protein family that this protein belongs to?
Belongs to the trichothecene 3-O-acetyltransferase family.