PharMolix/UniProtQA huggingface dataset:
Protein: HTPG_ACIF5
Sequence: MAASKETMQFQTEINQLLQLMIHSLYSNKEIFLRELISNASDACDKLRFEALADPALLTGDSELKVEVDFDPEAGTITVRDNGIGMNRDEVIANIGTIAKSGTREFFERLSGDQTKDAKLIGQFGVGFYSAFIVADRVSLNTRRAGMEAEHGVRWESDGTGTYTLETLDLPARGTEIVLHLREEERQDLLSAWRLRSIINKYSDHIPLSIRMRKIGEGGKPGDEWETVNKASALWQRSKSEISDDEYKEFYRYVSHDYGDPLTWSHNHVEGRLEYTSLLFIPAKAPFDLWDHNHPHGIKLYVQRVFIMDDAEQLLPRYLRFVRGVIDSSDLPLNVSREILQGNRVIDQMRSGSVKRILGLLEEMAEKEPEKYQTFWNEFGRVLKEGPGEDYSNREQIARLLRFASTHTDTDTQNVSLADYLARMAEGQDKIYYITADSFLAAKNSPQLELLRKKGIEVLLLSDRVDEWLTSHLPEFEGKALTSVAKGALDLGAIETEEERKSQEETEKDAEGLVERIKNALGERVETVRVSHRLTSSPACIVLGERDMALYMQQLLKQAGHEISSTKPVLEINPTHPMLARIEGEKDDTRFAEWSALLLDQAILAEGGQLEDPAGFVARINQLMLALAG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESL1_MYCPN
Sequence: MRLEIENGLEFVCDPFLNERGKIFFLHAFTGNITNKLSFRTHFKDYSFYGINFPGHGNSVIHNQSELDFNFWIKLVQQFFNKYQLKNVVLFGHSIGGGLAIALTQVLTKEQIKGIILEAPLNPGIRATPPSIISALVPDTNEDFEAVQRALIYNIEQRFGANFKDFCAKQKQKMIQKYAPLKVMLQPEQAEQRLQLIDAAFKRLSYPTLWIHGQEDGIVRYLPSKAYLESLHNPLIELVGLSNTAHTTFFEQPQQFLQLVEQFLNKLNK
What are the official names of this protein?
Putative esterase/lipase 1.
What is the protein family that this protein belongs to?
Belongs to the lipase/esterase LIP3/BchO family.
Protein: RL20_NOCSJ
Sequence: MARVKRAVNAQKKRRVVLERASGYRGQRSRLYRKAKEQVTHSLVYSYNDRRKNKGNFRKLWIQRINAAARAQGMTYNRFIQGLNLAGVEVDRKILADLAVNDVTAFNALVETAKAALPADVNAPKAEASA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SPC2_SCHPO
Sequence: MPKYNVSDFKSKFDKELTNHFNKNGYKQSFVFEDIRLLIAIACIIPAGLAFGIEYVYGFGVLKSYLKYLLPLYFLASCLLTFWSSVVKGSTVYVATKKERHIKISADTFLPLKNKPLITTKFTVLKNRNAVQLEWSVPVAHIFEEDGQISSATFEAEISKYLSQIEN
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
Protein: CCG7_MOUSE
Sequence: MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC
What is the function of this protein?
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity).  Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (By similarity).  Shows specificity only for GRIA1 and GRIA2 (By similarity).
What are the official names of this protein?
Voltage-dependent calcium channel gamma-7 subunit, Neuronal voltage-gated calcium channel gamma-7 subunit, Transmembrane AMPAR regulatory protein gamma-7, TARP gamma-7.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_DESHY
Sequence: MPRIKICGIRTGEEARWAVEAGADALGFIFVPHSKRYIQPETAREIILNLPPLISKVGVFAQASPEHVGRIVHECSLDTIQLHGNEDPRLYRHLSVTKIKAFSFPSAPAPGNSSEAAPDFSLVETSPSSSLPTSFRELPPASLHGILLDSSAGGRTGGTGIPLPWHTPVFQDFLHQVGDLGYPLILAGGLNPDNILEAIRLTRPYGVDVSSGVERNGRKDREKIQHFISQARKESPL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: MALR_STRPN
Sequence: MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKELNYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIATGKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPLVDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNRIYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDSVNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK
What is the function of this protein?
Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP.
What are the official names of this protein?
HTH-type transcriptional regulator MalR, Maltose operon transcriptional repressor.
Protein: YOEB_ECOLI
Sequence: MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY
What is the function of this protein?
Also shown in vitro to be a translation initiation blocker.  Binds to the 70S ribosome and 50S ribosomal subunit; binding is inhibited by hygromycin A and tetracycline, both of which bind to the 30S subunit in the A site.  Thus YoeB is located at the interface between 50S and 30S ribosomes and interacts with the A site where it cleaves mRNA, blocking translation initiation.
What are the official names of this protein?
Toxin YoeB, Putative endoribonuclease YoeB, Putative mRNA interferase Yoeb.
What is the protein family that this protein belongs to?
Belongs to the YoeB family.
Protein: PETN_SOLTU
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: SCPB_STRP6
Sequence: MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQKYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQPITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHLDELIEVSAVEPADEEIALFRTQD
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: URE3_MICLC
Sequence: MHLQPKDLEKLLVVVAADLARRRQQRGLKLNHPEAIAIITYELMEGARDGRSVADLMSWGSTILTVDDVQEGVADMISMVQVEATFPDGTKLVTVHDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_RHIEC
Sequence: MAGSKCLALIAHDQKKDDMAAFARANQELLSRWKIVATGTTGGRVLDAAPDLDVTRLKSGPLGGDQQIGALISTGEVDALIFFVDPLTPMPHDVDVKALMRLAIVYDIPMALNHATAIKLLPTLEA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RNPH_SHEPW
Sequence: MRPSNRTPAQSRPVTITRQFTAHAEGSVLVEFGDTKVLCTASFEEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMNREAARGKQSGRTQEIQRLIGRSLRAAVDMKLLGENTIVIDCDVIQADGGTRTAAITGACVALVDALNWARGKGILKTNPLKFLIAAVSVGIYKGEPICDLEYIEDSAAETDMNVVMTETGKMIEIQGTAEGEPFTHEELLSLLDLAKHGIREIVDIQKASLS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GLPB_HAEIE
Sequence: MNFDVAIIGGGLAGLTCGIALQQRGKRCVIINNGQAAIDFASGSLDLLSRMPSTTYGENRAVENLKENITALRNELPAHPYSLLGAEKVLAKAQDFERLANELHLDLIGSTEKNHWRVTGLGSLRGAWLSPNSVPTVQGNELFPHKRIAVLGIEGYHDFQPQLLAANLVLNPQFEYCEVTSGFLNIPQLDELRKNAREFRSVNISQLLEHKLAFKDLVKEIIESSQGAEAVFLPACFGLENQEFMTALRDATKLALFELPTLPPSLLGMRQRIQLRHKFESLGGLMINGDSALNATFEGNKVRCINTRLLEDEEITADNFVLASGSFFSKGLISEFDKIYEPVFESDIIGVEGFNQKDRFTWTVHRFAHPQPYQSAGVAINAQCQVKKCGQFLTNLYAVGNVIGGFNALELGCGSGVAVVTALAVADEILAK
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: RL3_ECOLU
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TYSY_DROME
Sequence: MVLTPTKDGPDQESMPLPADNGESPSKQQAPVNRDEMHYLDLLRHIIANGEQRMDRTEVGTLSVFGSQMRFDMRNSFPLLTTKRVFFRAVAEELLWFVAGKTDAKLLQAKNVHIWDGNSSREFLDKMGFTGRAVGDLGPVYGFQWRHFGAQYGTCDDDYSGKGIDQLRQVIDTIRNNPSDRRIIMSAWNPLDIPKMALPPCHCLAQFYVSEKRGELSCQLYQRSADMGLGVPFNIASYALLTHMIAHVTGLKPGDFVHTMGDTHVYLNHVEPLKEQLERTPRPFPKLIIKRQVQDIEDFRFEDFQIVDYNPHPKIQMDMAV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: CK096_RAT
Sequence: MAFAVIRACSRVGRGGLYKRLGGLPRGTRRQRQRRQGASLSTTEQRSLAPRPPTGPPARYPSPAVPARASEARRHPAADLDPPPGEPQAVASRGTPEPRPPPESPGAQPPPGPAAADGAMAAAKPGELMGISSSYQAVMPHFVCLADEFPQPVRPAKLPKGKGRLRRPRQSRFKTQPVTFDEIQEVEEEGVSPMEEEKAKKSFLQSLECLRRSTQSLSLQREPLGSCKLRNSLDSSDSDSAL
What are the official names of this protein?
Uncharacterized protein C11orf96 homolog, Protein Ag2.
Protein: LEPA_YERPG
Sequence: MKHIRNFSIIAHIDHGKSTLSDRIIQICGGLSEREMAAQVLDSMDLERERGITIKAQSVTLDYHSKDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAIRCSAKTGVGVPDVLERLVRDIPAPEGDPNGPLQALIIDSWFDNYLGVVSLIRIKNGSLRKGDKVKVMSTGQSYNADRLGIFTPKRVDRDVLNCGEVGWLVCAIKDILGAPVGDTLTLTRNPAEKSLPGFKKVKPQVYAGLFPISSDDYESFRDALGKLSLNDASLFYEPESSTALGFGFRCGFLGLLHMEIIQERLEREYDLELITTAPTVVYEVITTNQETVYVDSPSKLPALNNIEELREPIAECHMLLPQEYLGNVITLCIEKRGTQTNMVYHGKQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQTSDMVRVDVLINNERVDALALITHRDNAQYRGRDLVEKMKELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKDGKKRMKQVGNVELPQEAFLAILHVGKDSK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAA_ECO57
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKSVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZTRF1_MOUSE
Sequence: MSGAEEAGGGGPAAGPAGAVPAGVGVGAGPGAAAGPAAAALGEAAGPGIPDEAALAGARQLQEAAGDPDAPPKKRLRAAEAAEAAAAAVAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEECQDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLLSFEKIGYTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLSFQLLLKSKVTAPLECSFLLLKGPYDDVRISPVIYHFVFTNESNETDYVPLPIIDSVECNKLLAAKNINLRLFLFQIQK
What are the official names of this protein?
Zinc finger TRAF-type-containing protein 1, Cysteine and histidine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZFTRAF1 family.
Protein: EFP_BURCH
Sequence: MKTAQELRVGNVVQIGSEAWVIAKAEYNKSGRNSAVVKMKMKNLLSNAGQESVYKADDKFEVVVLDRKEVTYSYFADPMYVFMDADYNQYEVEAEMMGEALNYLEDGMACEVVFYNEKAISVELPTVLVREITYTEPAVKGDTSSGKVLKNAKLATGFELQVPLFCNTGDKIEIDTRTNEYRSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPED_ALKMQ
Sequence: MDIKSFEKIQLYGFNNLTKTLSFNIYDICYAKAPEQSKAYIAYIDEQYNAERLTKILSNVADITGANILSISKQDYDPQGASVTMLVAEEMTVPTLTPESLTGESPGPLPGNKPSPGSIVTHLDKSHVTVHTYPETHPLDGISTFRADIDVSTCGHISPIKALNYLIHSFESDIVTIDYRVRGFTRDINGQKYFIDHDINSIQNYIAKDILNLYHAIDVNVYQENIFHTKMTLKDFKLNNYLFGVSEEELSDHESASIKDQLRDEMQEIFYGRNVTKV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: RS15_SYNSC
Sequence: MSLDTTEKQQLINTHQTHGTDTGSAEVQVAMLSERINRLSRHLQNNIHDFSSRQGLLKMIGRRKRLLSYMRSKSEQRYADTIAKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: UVRB_LACPL
Sequence: MIDRVDNNHFDLVSDYQPTGDQPQAIQQLTAGIESGEKEQILLGATGTGKTFTISNVIAKVNKPTLILSHNKTLAGQLYGEFKKFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSAINDEIDKLRHSATSSLLERNDVIVVASVSSIFGLGDPHEYQDHVVSLRVGMEIDRNDLLRKLVDIQFDRNDIDFQRGRFRVHGDVVEIFPASRDDHALRVEFFGDEIDRIREIDALTGEIVADREHVAIFPATHFMTNDAIMEHAIKGIEDELDGRLKELTADGKLLEAQRLKQRTTYDVEMLKEMGYTSGIENYSRFMDGRKPGEPPYTLLDFFPKDFLLVVDESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLKLEEVEQHINQVVYMSATPGPYEMDRTKHVVQQIIRPTGLLDPTIEVRPIMGQIDDLVGEINKRIEVNERVFITTLTKKMAEDLTDYFKDLGIKVRYLHSDIKTLERTQIIRDLRLGKFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERSLIQTIGRAARNEHGSVIMYADTTTDSMQAAMDETARRRAVQMKYNEDHHITPHTIKKAIPELIASTKTTEDAGKKDDFLETDFDDMTREQQLDMISKLEEQMKTAAKKLDFEQAATLRDTVMELKAQIS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_ACIAD
Sequence: MSNISDIILASSSQTRKALMDRLGLTYRIISPDIDESPQGETHADDLAQRLAFEKARVVSAQYPNSIVIGSDQVAWRIDLPKQFIGKPLTIENAMAQLKQNSGQTLCFSTGLSIQHLASGFEHTLIEHYQVKFRVLTDAEIERYVTTEQPLQCAGSFRCEGLGISLFESMQGSDQTTLMGLPLITLCKYLRQLNIQLP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN21_RAT
Sequence: MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELREITYFSLWYYNKQNQRRWVDLEKPLKKQLDKHALEPTVYFGVVFYVPSVSQLQQEITRYQYYLQLKKDVLEGNLPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALLPVGWLQDEKLLEEAAQKVALLHQKYRGLTAPEAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLDGIFVKHKNGRPPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYVWRLCVARHKFYRLNQCNLQTQAATLNSVRRGSSSRMSLPKPQPYAMPPPPQLHYNGHYTEPFASSQDNVFVPNKNGFYCHSQTSLDRTQIDLSGRIRNGSVYSAHSTNSLNTPQPYLQPSPMSSNPSIPGSDVMRPDYIPSHRHSALIPPSYRPTPDYESVMKRLNRGMVHADRHSHSLRNLNIGSSYAYSRPDALVYSQPEIREHPHLASPQSAHYPFNLNYSFHSQAPYPYPVERRPVVGAVSVPELTNVQLQAQDYPAPNIMRTQVYRPPPPYPYPRPANSTPDLSRHLYISSSNPDLITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAHLQKRNSIEIAGLTHGFEGLRLKEETMSASAADVAPRTFSAGSQSSVFSDKVKQEGTEEQGSGGYSHKKSLSDATMLIHSSEEDEDLEDDSSREHAVSEPRLTAAFSQEQQLNYPCASVTPVTGPLHIFEPKSHVTEPEKRAKDISPVHLVMETHQPRRHGLLTPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNTVEGLPPLGGMKKTRADAKKIGPLKLAALNGLSLSRLPLPDEGKEVSTRATNDERCKVLEQRLEQGTVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDARVELVPTKENNTGYINASHIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGVAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSEPRSPNPPLLVHCSAGVGRTGVVILSEIMVACLEHNEVLDIPRVLELLRQQRMMLVQTLSQYTFVYRVLIQFLKSSRLI
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 21, Protein-tyrosine phosphatase 2E.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PUR9_SERP5
Sequence: MQQPRPIRRALLSVSDKAGIVEFAEALSQRGVELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMGQHDIKPIDMVVVNLYPFAQTVARPNCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYAAIITEMDNNDGSLQYTTRFDLAIKAFEHTAAYDSMIANYFGALVPAYHGDTEQPAGRFPRTLNLNYIKKQDMRYGENSHQQAAFYIEENVQEASVATAEQLQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGDDILSAYERAYQTDPTSAFGGIIAFNRELDAATAQAIISRQFVEVIIAPSISQEARSLLAAKQNVRVLACGQWQQRIAALDFKRVNGGLLVQDRDLGMVSEGDLRVVSERQPTAQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGISCVIQPGGSIRDDEVIAAANEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RNFH_ACTSZ
Sequence: MEQINIEIAYAYPHNHYLKSFTLDAGTTVQSAILQSGILAQYTDIDLRKNKIGIFARPVKLTDVLKNGDRIEIYRPLLADPKEIRRKRAAQQAARQKGKI
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: LPLT_SHIF8
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILLAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASAIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAARPGQSWNLINMTRSFLNACTSLWCNGETRFSLVGASLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERD23_XENTR
Sequence: MNVFRISGDVSHLLAIIILLLKMWKSKSCAGISGKSQLLFALVFTTRYLDLFTVFISAYNTVMKIVFLVCAYVTVYLIYGKFRKAYDSENDTFRLEFLLVPVIGLSFLENYEFTPLEILWTFSIYLESVAILPQLFMISKTGEAESITTHYLFFLGLYRVLYLANWIWRYHTEKFYDQIAVVSGVVQTIFYFDFFYLYITKVLKGKKLSLPMPV
What is the function of this protein?
Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.
What are the official names of this protein?
ER lumen protein-retaining receptor 3, KDEL endoplasmic reticulum protein retention receptor 3, KDEL receptor 3.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.