PharMolix/UniProtQA huggingface dataset:
Protein: RN126_HUMAN
Sequence: MAEASPHPGRYFCHCCSVEIVPRLPDYICPRCESGFIEELPEETRSTENGSAPSTAPTDQSRPPLEHVDQHLFTLPQGYGQFAFGIFDDSFEIPTFPPGAQADDGRDPESRRERDHPSRHRYGARQPRARLTTRRATGRHEGVPTLEGIIQQLVNGIITPATIPSLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVSFSSSSSSSSSSSPSNENATSNS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins (PubMed:23277564, PubMed:24275455, PubMed:24981174).  Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates (By similarity).  Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome.  Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome (PubMed:24981174, PubMed:29042515).  May also play a role in the endosomal recycling of IGF2R, the cation-independent mannose-6-phosphate receptor (PubMed:24275455).  May play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, FLT3, MET and CXCR4, by mediating their ubiquitination (PubMed:23418353).  By ubiquitinating CDKN1A/p21 and targeting it for degradation, may also promote cell proliferation (PubMed:23026136).  May monoubiquitinate AICDA (PubMed:23277564).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF126, RING finger protein 126.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAND_MYCTO
Sequence: MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_AROAE
Sequence: MAMTRSLEVKGQLVAGGKEPLICAPLVGRDEAAVLRELEVIVAKRPDLLEWRVDFYSGISDVERVVELAKEIRRSSAGIPVIFTRRSTREGGEPIGLSEDEVLSMYRAVARSGAVDFLDYELSSQPEHFEQAVALARETDTKLIASFHDFGKTPPVDEIVAKLVAMEEAGADIAKVAVMPQGLEDVLTLLQATLEAQKKIRLPVISMSMGAYGSLSRLFGWVFGSSVSFAVGQQASAPGQVPIEDLRTVLEVLQRSLKGE
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PANB1_ALIF1
Sequence: MKKISIHDLMKWKQEGKKFATVTAYDASFAQLFEQQEVPVLLVGDSLGMVLQGKSDTLPVTTEEIAYHTRCVRAGSPNSLLMADMPFMSYATPEQACENAGKLMQAGANMVKIEGGEWIAETVRVLAERAVPVCAHLGLTPQSVNIFGGFRIQGRDEAKAEQMVKDALTLEAAGAQIILLECVPASLAERITKACTVPVIGIGAGNVTDGQILVMHDMFGISANYMPKFSKNFLAETGDMRKAVTKYIQDVEQGVFPVAEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP6_HUMAN
Sequence: MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSAPPEEQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACLLLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMFAPCGDGSTAGES
What is the function of this protein?
Has an essential role in spermatogenesis (PubMed:36150389).  It is required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (By similarity).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).  Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis (By similarity).  May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).
What are the official names of this protein?
Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, 36 kDa FKBP, FKBP-36, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36.
What is the protein family that this protein belongs to?
Belongs to the FKBP6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Chromosome. Note=Does not localize to pi- bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity).
Protein: COAA_SHEAM
Sequence: MINNQTQEALYLDFDRARWAELRNSVPLTLSEADLTRLRGINERISLSEVTDIYLPLSRLLNLIVGARQQRGLVLNQFLGNKQPDSPYVISIAGSVAVGKSTTARILQALLKQWPEHPKVDLVTTDGFLYPLTELKRKGLLQRKGFPESYDTKMLIDFVSAVKSGAERVEVPLYSHIIYDRLPYERQVIQKPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDADESLLKSWYIERFLQFRSSAFADENSYFRHYASLNDTQATETASQIWDGINGPNLRMNIQPTRERAHLILRKGADHLMNRVLLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_GRAFK
Sequence: MDFSSKLLEQAVDEMSQLPGIGKRTALRLVLHLLKQPEEQTTQLSKALLELRQNIKLCNNCYNISDTELCEICANPSRVSEIVCVVEDIRDVMAIENTGQYRGHYHVLGGKISPMDGIGPSQLTIKPLIEKVQAGKIDEIIFALSSTLEGDTTNFYIFKQLEGTAIKTSTIARGISVGDELEYADEVTLGRSITNRIPFENSMKS
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: LPXH_YERP3
Sequence: MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSEHIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CA074_XENLA
Sequence: MASSLHKHLLSAARHHLKETKRMSMMVALNLAAEILAVDCGLKPCFLYDYTTSGVQQICSYLKELQNLGLIVGHLHILNVEETILIINVTKAVSYLETLLHSQDLHLIDVSNYLSQPELVSSNQVPQIHAQLAELLGHIKPYQSGQPTSVSVGGIQSPEWNLCTMFGFLLQFPSTYWFDTQKGFENCLSFTPLRLFTVQANCSRIGHQSVQIYSFTVPECVYQATQVHLEDWSKSLKQAFNEQNYFTDLEIITNTAQVCCVY
What are the official names of this protein?
UPF0739 protein C1orf74 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0739 family.
Protein: MCLA_CHLAA
Sequence: MRKLAHNFYKPLAIGAPEPIRELPVRPERVVHFFPPHVEKIRARIPEVAKQVDVLCGNLEDAIPMDAKEAARNGFIEVVKATDFGDTALWVRVNALNSPWVLDDIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMVNLEEIAGASPRMHGFSLGPADLAASRGMKTTRVGGGHPFYGVLADPQEGQAERPFYQQDLWHYTIARMVDVAVAHGLRAFYGPFGDIKDEAACEAQFRNAFLLGCTGAWSLAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLARMIAKKDPDLAQAYGL
What is the function of this protein?
Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation, and in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis.  As a part of the 3-hydroxypropionate cycle, it catalyzes the cleavage of (S)-malyl-CoA to yield acetyl-CoA and glyoxylate.  As part of the glyoxylate assimilation cycle, it catalyzes the condensation of glyoxylate with propionyl-CoA to yield (2R,3S)-beta-methylmalyl-CoA, and catalyzes the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruvate (By similarity).
What are the official names of this protein?
Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase, (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase, (3S)-citramalyl-CoA pyruvate-lyase, (S)-citramalyl-CoA lyase, Erythro-beta-methylmalyl-CoA, L-malyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: RRP41_PYRAB
Sequence: MMEKPEGLKLIDENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGYLTKDEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEVEGSE
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails (Probable).
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_ELUMP
Sequence: MARYEKQEKKDFVRKNEQIRVPQVRLIDSDGTMLGVKSVTEALYLAKQQELDLVEISPTAEPPVCKILDYSKYLYEQGKKLKDAKKKTAKTAMKELRIKSRIASHDLEVKIKHIEDFLKRKDMVRLVVVFHGRENQHRDLGEQMLHDVAKRLEPIANVEGGLQVTGNRMSMIFVPKN
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_ECOBW
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: CED4_CAEEL
Sequence: MLCEIECRALSTAHTRLIHDFEPRDALTYLEGKNIFTEDHSELISKMSTRLERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLEDYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMCDLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDILLMLARVVSDTDDSHSITDFINRVLSRSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEETIRWAQELRLRCLVTTRDVEISNAASQTCEFIEVTSLEIDECYDFLEAYGMPMPVGEKEEDVLNKTIELSSGNPATLMMFFKSCEPKTFEKMAQLNNKLESRGLVGVECITPYSYKSLAMALQRCVEVLSDEDRSALAFAVVMPPGVDIPVKLWSCVIPVDICSNEEEQLDDEVADRLKRLSKRGALLSGKRMPVLTFKIDHIIHMFLKHVVDAQTIANGISILEQRLLEIGNNNVSVPERHIPSHFQKFRRSSASEMYPKTTEETVIRPEDFPKFMQLHQKFYDSLKNFACC
What is the function of this protein?
Prevents programmed cell death.
What are the official names of this protein?
Cell death protein 4.
Protein: NUSB_STRZT
Sequence: MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDTDVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFDTPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PCRB_GEOKA
Sequence: MEEIRAWRHVFKLDPNKPIDDERLERLCESGTDAVIVGGTDGVTIDNVLDLLARIRRFSVPCALEVTDVEALTPGFDVYLVPIVLNSRQAEWIIGRHHEAVKQYGDMMNWDEIAAEGYCILNPECKAAKLTRADTELDVDDIVAYARLAEHLYKLPIFYLEYSGVYGDPSVVEKVKQALDQTQLFYGGGITTPEQAEHMARYADTVVVGNAIYDAFEQALATVAAVKQMAGQRNGDDGK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.  To a much lesser extent, is also able to use geranylgeranyl diphosphate (GGPP; C20) as the prenyl donor.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: Y2110_YERPS
Sequence: MDLNNRLTEDETLEQAYDIFLELAGDNLDPADILLFNLQFEERGGAELFDPAEDWQEHVDFDINPDFFAEVVIGLADSDGEEINDIFARVLLCREKDHKLCHILWKE
What are the official names of this protein?
UPF0263 protein YPTB2110.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: RL3_TREPA
Sequence: MVGLIGQKVGMTQIFDARGCVTPVTVIRVEHNVVVGLKDVERFGYSAVILGTGCMKKSRISKPYAGQFAERIPPVRVMREFRGFTLDVSVGQVLDVRVLESVRYLDVCALSKGKGFQGVVKRWGFSGGRSSHGSKFHREAGSTGQCTSPGRTFKNVKMPGRMGAERVTVQNLRIERIDVGLGVVMVRGAVPGRNKATVFLRTAVKRER
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: XPP3_RAT
Sequence: MLSLLSTPRLVPVIARLRGLSGCMSCLQRRYSLQPVPVKEIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKATSKNKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDLGIIKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIEQICSRTS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala.  Also shows low activity towards peptides with Ala or Ser at the P1 position.  Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity.  May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.
What are the official names of this protein?
Xaa-Pro aminopeptidase 3, X-Pro aminopeptidase 3, Aminopeptidase P3, APP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Note=Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation.
Protein: CENPP_HUMAN
Sequence: MDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINIRNHSKQTEDLTSTEMTEKSIRKVLQRHRLSGNCHMVTFQLEFQILEIQNKERLSSAVTDLNIIMEPTECSELSEFVSRAEERKDLFMFFRSLHFFVEWFEYRKRTFKHLKEKYPDAVYLSEGPSSCSMGIRSASRPGFELVIVWRIQIDEDGKVFPKLDLLTKVPQRALELDKNRAIETAPLSFRTLVGLLGIEAALESLIKSLCAEENN
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
What are the official names of this protein?
Centromere protein P, CENP-P.
What is the protein family that this protein belongs to?
Belongs to the CENP-P/CTF19 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein: COXZ_SINMW
Sequence: MADTGQSDRKERSNGVIVGTCLAFVVGMVGMAYAAVPLYDMFCRVTGYNGTTQRVEQESDLILDEKVKVTFDANVAAGLPWEFAPVQRDIDVRIGETVQITYRARNLASTPTTGQATFNVTPMAAGAYFNKVQCFCFTETTLQPGEEMEMPVVFFVDPEIVKTVETKGIKTLTLSYTFYPREPSKPVAQVKSRTENKL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: MK67I_HUMAN
Sequence: MATFSGPAGPILSLNPQEDVEFQKEVAQVRKRITQRKKQEQLTPGVVYVRHLPNLLDETQIFSYFSQFGTVTRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMNNYLFGERLLECHFMPPEKVHKELFKDWNIPFKQPSYPSVKRYNRNRTLTQKLRMEERFKKKERLLRKKLAKKGIDYDFPSLILQKTESISKTNRQTSTKGQVLRKKKKKVSGTLDTPEKTVDSQGPTPVCTPTFLERRKSQVAELNDDDKDDEIVFKQPISCVKEEIQETQTPTHSRKKRRRSSNQ
What are the official names of this protein?
MKI67 FHA domain-interacting nucleolar phosphoprotein, Nucleolar phosphoprotein Nopp34, Nucleolar protein interacting with the FHA domain of pKI-67, hNIFK.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Localizes to mitotic chromosomes in conjunction with MKI67.
Protein: QUEF_STRT1
Sequence: MSQQEEMKNLTLLGSKETPYIFEYSPQVLESFDNRHADNDYFIKFNCPEFTSLCPITGQPDFASIYISYIPDQLCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVELLNPRYLEVWGKFTPRGGISIDPYYNYGRPKTKYENMAEQRLFNHDLYPENIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PROM9
Sequence: MPKSEIHPKWYPDAKVICNGEVVMTTGSTQPELHVDVWSGNHPFFTGTQKILDTEGRVDRFMKKYGMGSANSATSKEQKEEKDSNK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HIS2_SULIN
Sequence: MSNEIVDKLYKVILDRIEKRPTGSYTAEIVNKGKAYVARKVGEESVETIVASLAENKERFISEVADLIYHLLVLMALEGVTPDDIYRELERRRK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TT21A_MOUSE
Sequence: MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPALQFFRAYGILGEDHIHDAISELEGIQSHPDTSLCAVIALLSAHKSCDTIDIEAVQELESSLKEIRRSASSTALYYASLFLWFMGHHDKAREYVDHMLKVSSGSKEGYVLKGWVDLTSSKPHVVKKSIKYLEQGTQDTKDVLGLMGKATYFMTQQNFSGALEVANQVTLACSNFLPALVLKMKLFLARQDWDQTIETGQRILEKDENNIDAWQILAVHELVKEGNTDRAADRVRNLIKALETGEPHNPNLHLKKILVISRLCGRHQVVHRLVSGFLERIFMATPSCALVATELGYLFILHQQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQQSLGKSELLVFLQALVAAKKQRLEQEATALLKEAVEVHFSSMQGLALSPEYFEKLDPLFLVCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLYVTAQVKFLSGELENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVRDHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKSQSPSVRPSERASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALNMLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCYVELCEHLPGPHSSLLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKISGQDFLCCELAELLLKLKKYHKAEKVLKQALERDSGVKDIPSMINEVKCLLLLAKVYKSHKKEEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQIGEHHLAEKDYDSALKSYKDALAYSPTDSKVVLELAHLYLLLGQLDLCEQRCAPLLEMEQTHERAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLEEAPAFFELAKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPDNEIVGGEAFESLVGDSNSASRKESQQHGVRTAEKLLREFYPHSESGQTQLRLLQNLCLLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWTVDEAEDLEKSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKDAATNYELAWKYSHQANPAIGFKLAFNYLKDKKFVDAIEVCHSVLTEHPKYPKIREEILEKAQGSLRP
What is the function of this protein?
Intraflagellar transport (IFT)-associated protein required for spermatogenesis (PubMed:30929735).  Required for sperm flagellar formation and intraflagellar transport (PubMed:30929735).
What are the official names of this protein?
Tetratricopeptide repeat protein 21A, TPR repeat protein 21A, Tetratricopeptide repeat-containing hedgehog modulator 2.
What is the protein family that this protein belongs to?
Belongs to the TTC21 family.