PharMolix/UniProtQA huggingface dataset:
Protein: FADA_PSYWF
Sequence: MTTLSPKDVVIVDGVRTAMGKSKNGMFRNVRADSMSAELVRALVKRNDFDTNEVEDIIWGCVNQTLEQGMNIGRNIGLLADIPKTAGGQTVNRLCGSSMQALHTAAAQIMTNQGDVFIIGGVEHMGHVGMMHGIDINPEASKHYAKASNMMGLTAEMLGRMNGITREQQDEFGYESHRRAWAATQAGRFDNEIIGIEGHDAEGRLQLCTVDEVIRPDTSMESLAKLRPVFDPANGTVTAATSSALSDGASAMLVMSAQKAKDLGLKPRARIRSMAIAGCDAAIMGYGPVPATQKALKRAGLTVEDMQTIELNEAFAAQGLSVLKALNLLDKRDIINVNGGAIALGHPLGCSGARITVTLLNAMEQMDTEIGLATMCIGLGQGISTVIERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_ERWT9
Sequence: MAAGEISTPQEYIGHHLNNLQLDLRTFELVNPHDAPATFWVLNIDSMFFSVVLGLVFLVLFRQVAKSATSGVPGKLQAAIELVIGFVDNNVRDMYHGKSKVIAPLALTIFVWVFLMNFMDLLPIDLLPYIGEHFLGLPALRVVPSADVNITLSMALGVFVLILFYSIKMKGIGGFSKELTLQPFNHPIFIPINLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILSVPWAIFHILIISLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MLTG_STRP2
Sequence: MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANEPSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSSPAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIRDTSRRSRREGAKPAKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAFLAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEMLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN
What is the function of this protein?
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation (By similarity).  Involved in peripheral peptidoglycan (PG) synthesis (PubMed:26933838).
What are the official names of this protein?
Endolytic murein transglycosylase, Peptidoglycan polymerization terminase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase MltG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Localizes separately from FtsZ with the peripheral PG synthesis machine.
Protein: XYND_ASPFC
Sequence: MSVAKSIAAVLVALLPGALAQANTSYVDYNVEANPNLTPQSVATIDLSFPDCENGPLSKTLVCDTSARPHDRAAALVSMFTFEELVNNTGNTSPGVPRLGLPPYQVWSEALHGLDRANFTDEGEYSWATSFPMPILTMSALNRTLINQIATIIATQGRAFNNVGRYGLDVYAPNINAFRSAMWGRGQETPGEDAYCLASAYAYEYITGIQGGVDPEHLKLVATAKHYAGYDLENWDGHSRLGNDMNITQQELSEYYTPQFLVAARDAKVHSVMCSYNAVNGVPSCANSFFLQTLLRDTFGFVEDGYVSSDCDSAYNVWNPHEFAANITGAAADSIRAGTDIDCGTTYQYYFGEAFDEQEVTRAEIERGVIRLYSNLVRLGYFDGNGSVYRDLTWNDVVTTDAWNISYEAAVEGIVLLKNDGTLPLAKSVRSVALIGPWMNVTTQLQGNYFGPAPYLISPLNAFQNSDFDVNYAFGTNISSHSTDGFSEALSAAKKSDVIIFAGGIDNTLEAEAMDRMNITWPGNQLQLIDQLSQLGKPLIVLQMGGGQVDSSSLKSNKNVNSLIWGGYPGQSGGQALLDIITGKRAPAGRLVVTQYPAEYATQFPATDMSLRPHGNNPGQTYMWYTGTPVYEFGHGLFYTTFHASLPGTGKDKTSFNIQDLLTQPHPGFANVEQMPLLNFTVTITNTGKVASDYTAMLFANTTAGPAPYPNKWLVGFDRLASLEPHRSQTMTIPVTIDSVARTDEAGNRVLYPGKYELALNNERSVVLQFVLTGREAVIFKWPVEQQQISSA
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase xlnD, 1,4-beta-D-xylan xylohydrolase xlnD, Beta-xylosidase A, Beta-xylosidase xlnD, Xylobiase xlnD.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TATA_CAMC5
Sequence: MAIGVNQLLIILVIIVLLFGAKKIPELAKGLGKGIKSFKAEMEDDKPIEKVEKKGDDVVDAKVEETTKNA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RNC_PHOV8
Sequence: MFSNIKDRIRLLFRKDRESYLRFYKMLGFYPKDISIYEQALLHKSLSVKSEKGRLLNNERLEFLGDAILDAVVADIVYKRFEGKREGFLTNTRSKIVQRETLNRLAIEIGLDKLIKYTARQSSHNSYMCGNAFEALVGAIYLDRGYRACKYFMEHRIIGPYINLEKISRKEVNFKSKLIEWSQKNRFEVTFELITQSHDQGYNPTFESEVLVEGISGGKGTGYSKKESQQMAARVALGKIKNDSGFIECIFAAKTARELPQEEVTVSDSKPSDSGAVTPDLSLEEIKKTDVVEQIISEAEEKAFKENA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIFI_ARATH
Sequence: MAAAANTSAVFASPSQPLSSKRSFLYSSRIGPILRRFPRKKLDLQVKAVATTLAPLEEIKEYKLPSWAMFEMGTAPVYWKTMNGLPPTSGEKLKLFYNPAASKLTLNEDYGVAFNGGFNQPIMCGGEPRAMLKKDRGKADSPIYTMQICIPKHAVNLIFSFTNGVDWDGPYRLQFQVPKRWQNKPIEFFNEGLANELSQDGACERAIFPDSNVVPTRCTMIANLTVEGGDRCNLDLVPGCMDTNSEHFNPYANVDDGSCPLELSDSDE
What is the function of this protein?
Required during nonphotochemical quenching (PubMed:17573537).  Involved in NAD(P)H dehydrogenase complex-mediated chlororespiratory electron transport which mediates electron flow from stromal reductants to the plastoquinone (PQ) pool during chlorophyll fluorescence increase after turning off actinic light, in response to photoinhibition conditions (e. g.  high light intensities), and upon long-term mild heat stress (PubMed:17573537).
What are the official names of this protein?
Protein POST-ILLUMINATION CHLOROPHYLL FLUORESCENCE INCREASE, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PYRDB_BACCQ
Sequence: MNRLQVELPGLSLKNPIIPASGCFGFGREYAQFYDLSVLGSIMIKATTEQPRYGNPTPRVAETPGGMLNAIGLQNPGLEKVMNSELPWLEQFDLPIIANVAGSQAEDYVAVAKEISKAPNVHALELNISCPNVKTGGIAFGTNPEIAADLTKRVKEVSEVPVYVKLSPNVANIVEIAKAIENAGADGLTMINTLLGMRLDLKTAKPILANRTGGLSGPAIKPVAIRMVHEVSQAVNIPIIGMGGIETAEDVIEFFYAGASAVAVGTANFIDPFVCPTIIEELPALLDELGFDHISECQGRSWKQTCHSR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_THET8
Sequence: MTAAVWTLLLAYLFGSVPAGVLVARTYGVDLRKVGSGNIGATNVLRALGWGPALVVAFFDVFKGGIAVLVARAFGLSDWMLGGVALMAVLGHNYSVFLRFRGGKGVATSFGTLLFLDPVLALWTFPIGLSVILLTRYVSAGSMTGGVAAFVLSLALGRPLWEVATVFLMALLIFWTHRENLKRLREGTERRLGERVEAR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSX_BURP6
Sequence: MTVKLTIDCMGGDHGPSVTVPAAVKFVRSHPDAHLMLVGIESAIRAQLKKCKALGEPALSVVPATEVVAMDDPVEVALRKKKDSSMRVALNHVKEGAAQACISAGNTGALMAVSRYVLKTLPGIERPAIAFALPNPTGYTMMLDLGANVDCEPQHLLQFAEMGHALVAALEGKERPTIGLLNIGEEVIKGNETIKRAGELLRASTLNFRGNVEGNDIYKGTVDVIVCDGFVGNVALKTSEGLAQMLADIIKEEFSRSLLSKLMAILALPVLLRFKKRVDHRQYNGAALLGLRSLVIKSHGSADAYAFEWAIKRGYDAVKNGVLERLSRAMAENAAPLGESGRDANGAGQASPSAGQPAEPSAALSSKT
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: FATE1_PIG
Sequence: MAGGSTNTKKIEMSLAEELVPKSQEPSREQVLIAEMLEHGIRSLGASQSRQKLDSKISDSAAAWNLAANKSKKTGPQLPPKKASQEPNQEGGFQGMGFLYERNLGADVIAEIGLEELNGLEMEIMRRQLQVITGRLRALEDQGATWRHRETLFFTMLVSVCVANLWLWLRQ
What is the function of this protein?
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling.  Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis.  May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
What are the official names of this protein?
Fetal and adult testis-expressed transcript protein homolog.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane. Endoplasmic reticulum membrane; Single- pass membrane protein; Cytoplasmic side. Note=Localized to specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. Also associated with the outer surface of mitochondria at sites that are not in close contact with the ER.
Protein: PANB_NOSS1
Sequence: MPVTTQQLIQWKQQGRSIVALTAWDYTIAQILDGAGVDLILVGDSMAVMLGYKTTLPITLEEMLHHAKAVCRGVQRALVVVDLPFLTYQESIPQAINSAGRILKETGAQAVKLEGGYPAMVDTINRLVQAGIPVMGHVGLTPQSVHQLGLRQQGKTQETAQRILNEAIALEQAGVFSIVLEHIPADLAMQITQKVNIPTIGIGAGSHCDGQVLVTSDVLGLSERQPPFAKVYTNLRETITKAVQDYAAEVRDRQFPE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_SHIBS
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHGKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: KYNU_BURM7
Sequence: MKTREEALALDRDDPLAPLREQFALPAGVIYLDGNSLGAQPRAAAARAQQVIGAEWGEGLIRSWNTAGWFALPRRLGDRLAPLIGAADDEVAITDTISINLFKLLAAMLRHQARHAPKRRVIVSERSNFPTDLYIAQGLIAQLDRDYELRLIDDPADLPDALDDETAVAMITHVNYRTGYMHDMPSVTQTVRQAGALMLWDLAHSAGAVPVDLNGALADGAVGCTYKYLNGGPGSPAFVWVPKRHQRAFEQPLSGWWGHRAPFAMQPAFEPDPGIARFLCGTQPIVSMSMVECGLDVFAQTDMHAIRRKSLALTDAFVALVESRCAGQPLKLVTPRAHHQRGSQASFEHPHGYEVMQALIARGVIGDYREPRILRFGFTPLYTRFVDVWDAVETLRDILDTEAWRAPEFATRAAVT
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: Y377_BLOFL
Sequence: MQKKLLEIIVCPFCYTRLFMNDTETELICNIENISFPLKQGIPVLLKNQIRYLNCKIIDNQ
What are the official names of this protein?
UPF0434 protein Bfl377.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NSP_SCSVF
Sequence: MADWFHSALKTCTHVCDFSDIKASSQQDFFCCDSMRGKLSEPRKVLLVSCFVSFTGSFYGSNRNVRGQVQLGMQQDDGVVRPIGYIPIGGYLYHDDYGYYQGEKTFNLDIESDYLKPDEDFWKRFTINIVNDKGLDDRCDVKCYVVHTMRIKV
What is the function of this protein?
Putative nuclear shuttle protein.
What are the official names of this protein?
Putative nuclear shuttle protein.
What is the protein family that this protein belongs to?
Belongs to the nanoviridae nuclear shuttle protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: L_MUMPM
Sequence: MAGLNEILLPEVHLNSPIVRYKLFYYILHGQLPNDLEPDDLGPLANQNWKAIRAEESQVHARLKQIRVELIARIPSLRWTRSQREIAILIWPRILPILQAYDLRQSMQLPTVWEKLTQSTVNLISDGLERVVLHISNQLTGKPNLFTRSRAGQDVKDYSIPSTRELSQIWFNNEWSGSVKTWLMIKYRMRQLITNQKTGELTDLVTIVDTRSTLCIIAPELVALYSNEHKALTYLTFEMVLMVTDMLEGRLNVSSLCTASHYLSPLKKRIEILLTLVDDLALLMGDKVYGVVSSLESFVYAQLQYGDPVVDIKGTFYGFICNEILDLLTEDNIFTEEEANKVLLDLTSQFDNLSPDLTAELLCIMRLWGHPTLTASQAASKVRESMCAPKVLDFQTIMKTLAFFHAILINGYRRSHNGIWPPTTLHGNAPKSLIEMRHDNSELKYEYVLKNWKSISMLRIHKCFDASPDEDLSIFMKDKAISCPKQDWMGVFRRSLIKQRYRDANRPLPQPFNRRLLLNFLEDDRFDPIKELEYVTSGEYLRDPEFCASYSLKEKEIKATGRIFAKMTKRMRSCQVIAESLLANHAGKLMRENGVVLDQLKLTKSLLTMNQIGIISEHSRRSTADNMTLAHSGSNKHRINNSQFKKNKDSKHEMPDDGFEIAACFLTTDLTKYCLNWRYQVIIPFARTLNSMYGIPHLFEWIHLRLMRSTLYVGDPFNPPSDPTQLDLDTALNDDIFIVSPRGGIEGLCQKLWTMISISTIILSATEANTRVMSMVQGDNQAIAITTRVVRSLSHSEKKEQAYKASKLFFERLRANNHGIGHHLKEQETILSSDFFIYSKRVFYKGRILTQALKNVSKMCLTADILGDCSQASCSNLATTVMRLTENGVEKDLCYFLNAFMTIRQLCYDLVFPQTKSLSQDITNAYLNHPILISRLCLLPSQLGGLNFLSCSRLFNRNIGDPLVSAIADVKRLIKAGCLDIWVLYNILGRRPGKGKWSTLAADPYTLNIDYLVPSKTFLKKHAQYTLMERSVNPMLRGVFSENAAEEEEELAQYLLDREVVMPRVAHVILAQSSCGRRKQIQGYLDSTRTIIRYSLEVRPLSAKKLNTVIEYNLLYLSYNLEIIEKPNIVQPFLNAINVDTCSIDIARSLRKLSWATLLNGRPIEGLETPDPIELVHGCLIIGSDECEHCSSGDDKFTWFFLPKGIRLDNDPASNPPIRVPYIGSKTDERRVASMAYIKGASVSLKSALRLAGVYIWAFGDTEESWQDAYELASTRVNLTLEQLQSLTPLPTSANLVHRLDDGTTQLKFTPASSYAFSSFVHISNDCQVLEIDDQVTDSNLIYQQVMITGLALIETWNNPPINFSVYETTLHLHTGSSCCIRPVESCVVNPPLLPVPFINVPQMNKFVYDPEPLSLLEMEKIEDIAYQTRIGGLDQIPLLEKIPLLAHLTAKQMVNSITGLDEATSIVNDAVVQADYTSNWISECCYTYIDSVFVYSGWALLLELSYQMYYLRIQGIQGILDYVYMTLRRIPGMAITGISSTISHPRILRRCINLDVIAPINSPHIASLDYTKLSIDAVMWGTKQVLTNISQGIDYEIVVPSESQLTLSDRVLNLVARKLSLLAIIWANYNYPPKVKGMSPEDKCQALTTHLLQTVEYVEHIQIEKTNIRRMIIEPKLTAYPSNLFYLSRKLLNAIRDSEEGQFLIASYYNSFGYLEPILMESKIFNLSSSESASLTEFDFILNLELSEASLEKYSLPSLLMTAENMDNPFPQPPLHHVLRPLGLSSTSWYKTISVLNYISHMKISDGAHLYLAEGSGASMSLIETFLPGEIIWYNSLFNSGENPPQRNFAPLPTQFIESVPYRLIQAGIAAGSGVVQSFYPLWNGNSDITDLSTKTSVEYIIHKVGADTCALVHVDLEGVPGSMNSMLERAQVHALLITVTVLKPGGLLILKASWEPFNRFSFLLTILWQFSSTIRILRSSYSDPNNHEVYIIATLAVDPTTSSFTTALNRARTLNEQGFSLIPPELVSEYWRRRVEQGQIIQDCIDKVISECVRDQYLADNNIILQAGGTPSTRKWLDLPDYLSFNELQSEMARLITIHLKEVIEILKGQSSDHDTLLFTSYNVGPLGKINTILRLIVERILMYTVRNWCILPTQTRLTLRQSIELGEFRLRDVITPMEILKLSPNRKYLKSALNQSTFNHLMGETSDILLNRSYQKRIWKAIGCVIYCFGLLTPDVEDSERIDIDNDIPDYDIHGDII
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MTNA_SYNY3
Sequence: MTQSTNFDDVYPVQWRDDQVILIDQTRLPLEYKEVAIADYEAMGHAIKSMVVRGAPAIGVAAAYGMYLGARRIQTTELREFVVQLEFVADQLRQTRPTAVNLFWAIDQMLNVAYHSGENVEQIKANLLSQAQQIQLDDLRTCQAIGAAGLEVLPREPHQLTILTHCNAGALATAGYGTAIGVIRAAWSAGRLARVYADETRPRLQGAKLTVWECVQAGIPVTLITDNMAAHCMQQQRIDAVVVGADRIARNGDIANKIGTYGLAVLAKMHAIPFFVAAPLSTVDFALDDGSQIPIEERDPVEIYQPEGNRITPEGAEFYNPAFDVTPASLITAIITEQGAIAPEKLADLQA
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: SAMH1_DANRE
Sequence: MENRIKRPRVDGECVKSINNGEFDRWDVEDTVAYLRGEGLQEWAQIFKDNGITGAGLLCLTEAHLEKMGVSPLGARLHILHCLQKLSQISTEPMKVFNDPIHGHIELHPLLLHFIDTPQFQRLRHIKQLGGTYLVFPGASHNRFEHSIGVGYLAGCLVKALNERQPELFITKQDILCVQIAGLCHDLGHGPFSHMFDGMFIPKARPADKWKHEIASVQMFDHLVEVNGLEAVMLHHGMRLPEDLIFIKEQIAGPLESAVLDQSQWPYKGRPVEKSFLYEVVANKRNGIDVDKWDYFARDCYHLGIQNNFDYQRFLRFARVCEVKGRKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITEAFLKADPHIQIQGSSGRIFTISSAIEDMEAYSKLTDHIFEQILYSSGPELSEARAILQNIICRRLYKCVGQTTSETNVDVSQEKLLDWAKELARSKPTGTEGNLIAEDFVVSVIHMDYGMKEKNPINNVHFYCKNDPTKAIKIHKKQVSKLLPERFAEQLIRVYCKKTDDKSLEAAKKYFVQWCMDRNFTKPQDGDIIAPELTPLKQDWHAREDEDEEEEEKHRQNQTLPHHTPQRTGRNVKVDLFQARGETKL
What is the function of this protein?
Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.  Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells.  Functions during S phase at stalled DNA replication forks to promote the resection of gapped or reversed forks: acts by stimulating the exonuclease activity of MRE11, activating the ATR-CHK1 pathway and allowing the forks to restart replication.  Its ability to promote degradation of nascent DNA at stalled replication forks is required to prevent induction of type I interferons, thereby preventing chronic inflammation.  Ability to promote DNA end resection at stalled replication forks is independent of dNTPase activity.
What are the official names of this protein?
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, dNTPase.
What is the protein family that this protein belongs to?
Belongs to the SAMHD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA double-strand breaks in response to DNA damage.
Protein: OBP_BPT5
Sequence: MFSILQGHAGFSRDLATGIWREIKAEDYTFAKRFSKEHPEGKPASMPFKFDVIEEHDPQSLAEMLPLMRRLTSDPHIVAVRGRCLAPKNNVRRKKGNFNVSNPSNIIAMDVDGILDTGGYDKFNLVGMARHIIKMLNSISEDMFPLDAGFIAHASSSAGLKPGIRMHLMLESNVKVTQGQLKFLFTSINDSSKQKFGFDIADLAYYSSVQLHYFADPLFSDGIVDPFKAESKPRLVYVKGSKVNLPNNLVDYETTRGEFKEEFYSLLDQIKGKKIASDKVEETISELEEADDGVYLRIIPKLYHRALEDGVDFAWLEREIKPALSEYIATKDNSRNIQDYFNNGRKQALKAFVNNSKREIPLNLKGVPLKKLEVDSPPEVPYLKINIVPPKGHITFVKASLGTGKTTAVTKWLDAGVLPGNFLAVTNTRALVSSNAKKFSAGQYDKSVDMLNFKRGAIDRMSTTIHSLHKFKSFIGQIDTIFIDECDAVMNDLLFAPVVKQRRECIQVLRDILMTAKTVILSDGDISAETIEAYGSLIDFDKPVAFYNHHRKMLSKAHAYEFPDESSIWVALQTSLEMGEKSILVSDCGPDELNEKGMALRRNTGALVKEIHSNSTSDVDIRRILDYTTNELIDQQIDCLLCSPSVTSGVDFNYFDNVFVITRTSNQAPNMRFQAIRRDRGAQNIYYFIDKSTSGFSAGSEQYNIDEGWLELAQQLYARRRELESRNYTSTLRYYLLDQGATIDIFSESWGTIEGAGKEYTEERIKAILHSTPDYCAPRHADAYEAKLLLVRYYHLESIKDVTVEHVEQYIKDKPNDRAAFFHKMHEMFWEDIKKCSNVTIKPFIEALKGKKKDFFLKTGQSANPKYARMYLGMMGIGKDMNTENIVDWYRTYCKIECMPIPFKFMTEEERAMAEEVMSELGATNEDA
What is the function of this protein?
Displays bipolar ssDNA and dsDNA unwinding activities that require the same core catalytic residues for unwinding in either direction, the 3'-5' direction being more robust.
What are the official names of this protein?
Putative replication origin binding protein, D2 helicase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae oribp family.
Protein: RNY_PELTS
Sequence: MAFCAGYFLRKYLAEAKIASAEAQAKKILEEAEKEAEAKKREAILEAKEEVLKLRNDMERENRERRLELQRLERRLVQKEETLDRKVDAIEKKEDALNRKEAEIDAIKAQLNEIYKKQLSELERISGMTSEEAKQALLSDIEKEIQHEAAMLIKEIESKAREEGEKRARDIISLAIQRCAADHVAEATVSVIPLPSDEMKGRIIGREGRNIRAFETLTGIDLIIDDTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAQKEVNVQIRDAGEQAVFETGVHGLHPELVTLLGRLKFRTSYGQNVLKHSIEVAHLAGLMASEIGVDIQMAKRAGLLHDIGKAVDHEVEGPHVAIGIDLAKKYREAQEIIHAIAAHHGDEEPKSIIAVLVQAADAISAARPGARRETLEAYIKRLTKLEEIANSFDGVEKSYAIQAGREVRIMVKPEKIDDLGAIRLVREITKKIENELDYPGQIKVVIIRETRVVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
Protein: SEEP_RAPSA
Sequence: MASQQEKKQLDERAKKGETVVPGGTGGKSFEAQQHLAEGRSRGGNTRKEQLGSEGYQQMGRKGGSTPDKTDKEDAEDEPSTRT
What is the function of this protein?
This protein may play a role in equipping the seed for survival, maintaining a minimal level of hydration in the dry organism and preventing the denaturation of cytoplasmic components, or may play a role during imbibition by controlling water uptake.
What are the official names of this protein?
Late seed maturation protein P8B6.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ERWT9
Sequence: MQFSKMHGLGNDFMVVDAVTQNVYFSPELIRRLADRHLGIGFDQLLIVEPPYDPDLDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKNEIRVSTQSGRMVLSITQDELVCVNMGEPNFEPQQIPFRANKAENIYLMRAAEQTVMCGVVSMGNPHCVLQVDNVKTAAVETLGPVLESHERFPERVNVGFMEVVHREHIRLRVYERGAGETQACGSGACAAVAVGIQQASLAEKVRVDLPGGSLHIAWKGPGHPLYMTGPATHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.