PharMolix/UniProtQA huggingface dataset:
Protein: DXR_WOLPM
Sequence: MKKVSVLGSTGSVGKKTVDLLSKRKEEYQVEALSAHSNFALLAHQAKLLNAKYVAISDERLYKDLKESLLGTDVKIAIGATNIATIPVDLSVVAIVGIAGLGPVMEVIESGTKVIALANKESIVCGGKLLLKKAKEKNVQIIPIDSEHNAIFQILQNDDKCVEKIILTASGGPFLNYSLEQLRNVMVDKALSHPTWNMGKKISVDSATMMNKALEIIEAHNLFNISPDKIEAIVHPESIVHGIVTYKDGFNFAVLAETDMAIPISYALSGPERSALNRKLDLTKQGKLTFQEPDHKRFPALKLSMAVLNSSAPQTNSIVLNAANEIAVNEFLKSRIGFLKIVEVVESTMESFGSYTDINSLSDIINIDYESRIIAHKIVESKVVAYS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: X_HBVGB
Sequence: MAARMCCQLDPSQDVLCLRPVGAESRGRPFSGPLGPLSPPSPSLVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARCMATTVNAPRSLPTVLHKRTLGLPAMSTTGIETYFKDCVFKDWEESGEETRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: TOLB_SHESH
Sequence: MKTFGKWLVLGLVILSSPVRAALDIVITEGIDAARPIAVVPFVWQGQGPAPQQISDVVMSDLTRSGTFKTLDELSLPQRNISAISQFQAKDWANVGAEAVVMGAIKPYGEDKYLVSFDLVDLVKAQMQSGTGPQSKQEFLIDSRETVISSAQFRQYGHRISDIIYEKLTGIRGAFLTRIAYVVVKHGEKSPYQLMISDYDGHNEQMLLRSPEPLMSPSWSPDGRQLAYVSFENKKAEIFIQDIYTQSRSKITSFAGINGAPVFSPDGKKLALTLSKDGQPEIYVVDISTKALKRVTNHYAIDTEASWFPDGKSLIFTSERGGRPQIYKVTLASGKVQRMTFEGEWNLGGSILPDGRSMIFVNRTNGKYNIARMDLETRFMQVLTSTRLDESPSVAPNGTMVIYGTTYQGKQVLAAVSTDGRFKARLPTGQGEVKSPSWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ESBP6_YEAST
Sequence: MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV
What are the official names of this protein?
Uncharacterized transporter ESBP6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HISZ_STAA2
Sequence: MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNHEDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQVGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILSMIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHTQGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTF_ELLSS
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, EllSp-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_PHYAM
Sequence: MSPQTETKASVGFKAGVKDYKLNYYTPEYKPQDTDILAAFRVTPQPGVPSEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIDPVAGEDNQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPIAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRLLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGAPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHALIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDHTEIDDARGIYFTQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGRVANRVALEACVQARNEGRDLASEGNVIIREASKWSPELAAACEVWKEIKFEFPAVDVFHKGKKKN
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BGAL_CITK8
Sequence: MPQNADSLAVVLKCRDWENPGVTQLNRLEAHPPFCSWRNADDARVNRDSAQKRSLNGEWTFAWFSAPEAVPESWRTSDLQQADSVRVPSNWQMDGYDAPIYTNVTYPIPVNPPFVPADNPTGCYSLTFSIDADWLQAGQTRIIFDGVNSAFHLWCNSRWVGYGQDSRLPSEFDLTHFLLKGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPATQIRDLRINTRFNDDFSRAVLEAEVRTTGERRDDLRVTVQLWDSETFVGEKTAPLGSEIIDERGAYPDRTTLRLNVEHPALWSAETPHLYRAVVQLHAADGTLIEAEACDVGFRQVSIENGLLLLNGKPLLIRGANRHEHHPENGQVMDKETMIKDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLSDDPVWLPAMSQRVTRMVQRDRNHPSIIIWSLGNESGHGANHDALYRWIKSEDPSRPVQYEGGGANTAATDIICPMYARVDQDQPFPAVPKWSIKKWLSMPGEQRPLILCEYAHAMGNSLGGYAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDDDGRPWSAYGGDFGDAPNDRQFCMNGLVFADRTPHPSLYEAKHAQQFFQFALLPGAECQIEVTSEYLFRHSDNEVLHWSLALDGNPLTAGVVTLDIPPQGRQIIALPALPEAETAGQLWLTVRVEQPQATAWSQAGHISAWQQWKLGEKLATQWPQHAGNAPQLTSSGTAFRIVAGEKRWEFSRQQGVLTQFWIGEEAQLLTPLVDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAKAVLLQCDADTLASAVLITTAHAWQYQGETLFISRKTYRIDGNGEMQITVDVDVASGTPHPARIGLSCQLAQVAERVNWLGLGPHENYPDRLSAACFERWDLPLEEMYTPYVFPSENGLRCGTRELLYGAHQWRGDFQFNISRYGQKQLMETSHRHLLQPEAGTWLNIDGFHMGVGGDDSWSPSVSAEYQLSAGRYHYQISWR
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: RK36_AGRST
Sequence: MKIRASVRKICTKCRLIRRRGRIRVICSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASIP_MACNG
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKSPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_ROSDO
Sequence: MRQGFPKARAGEVIGLFGGSFDPAHQGHAHITREALKRFGLDRVWWLVSPGNPLKPQGPAPLDTRMARAKAIMQHPRVIITDVETRLGTRYTAATLDQLSALYPGVHFVWLMGADNLAQFHKWQRWRDIASTTPLGVLARPGDRIPARMSPAAAVFGRARIPGRASQLLGRAAAPAWCFVNVPMVEQSSSAIRSKGGWV
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GCSH_BEII9
Sequence: MSITRYTKDHEYIRVEGETGTVGITDYAQSQLGDVVFVELPAIGKALTKGGEAAVVESVKAASEIYAPVSGEVVAVNEALAEAPGTVNEDAAGKGWFLQIKLADAKELDGLMDEAGYQDFLKTL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RECF_BACAH
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGTKILQKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HESX1_PANPA
Sequence: MSPSLQEGAQLGESKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCLHVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFNTNLLE
What is the function of this protein?
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland.  Possible transcriptional repressor.  Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'.  HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity).
What are the official names of this protein?
Homeobox expressed in ES cells 1.
What is the protein family that this protein belongs to?
Belongs to the ANF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRONC_DROME
Sequence: MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPGFFNE
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  Effector of steroid-mediated apoptosis during insect metamorphosis.  Overexpression promotes programmed cell death.  Interaction with Diap1 is required to suppress Dronc-mediated cell death; via Diap1-mediated ubiquitination of Dronc.  Rate-limiting caspase in rpr and hid death pathway.
What are the official names of this protein?
Caspase Dronc, NEDD2-like caspase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYB2_BOALU
Sequence: FIGAILPAIAGLVGGLINR
What is the function of this protein?
Has hemolytic activity against human erythrocytes.  May have antimicrobial activity.
What are the official names of this protein?
Hylin-b2, Hy-b2.
What are the subcellular locations of this protein?
Secreted.
Protein: LAC14_ORYSJ
Sequence: MAPSLGSGSTRILLIVSLLLCLRQQAVVDAAIVEHTFHVGNLTVERLGQRQVITAVNGQFPGPKVEARNGDTLLVRVVNNSPYNITIHWHGVLQRLSAWADGPAMVTQCPILPGSGAGSSYTYRFNVTGQEGTLWWHAHVSFLRATVYGALLIRPRPGVPYPFPAPHAEHTLLLGEWWNASATLVDVERQAFLTGGQPANSVALTINGMPGLSHAHKEMHHLRVARGNTYLLRLVNAALNYQLFFKVAAHNFTVVAVDACYTDPYHTDVIVIAPGQTVDALMHAGAAPGRRYYVAAQVYQSIANATYSATARALLRYDDDAKDAAKTIIMSPRMPVLNDSATAQRFYGSLTGLLRDGKPTVPQRVDTRMVVTYGLAIAPCLPAQTLCNRTRGSLAASMNNVSFQLPATMSLLEASRSRSSGVYTRDFPDRPPVMFDFTNAAAVNRNMSLMVTSKGTRVKALRYNETVEVVLQNTAVLGTENHPLHLHGFNFYVLAQGTGNYYYLIRKKKIRKNLVNPQQRNTIAVPPGGWAVIRFTADNPGVWLMHCHLEAHLPFGLAMAFDVQDGPTPDAMLPPPPNDYPPC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-14, Benzenediol:oxygen oxidoreductase 14, Diphenol oxidase 14, Urishiol oxidase 14.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: OTOGL_MOUSE
Sequence: MVPWRALSLPILLVSLRGYVCASSVLSETSESEFYENEQRRALLAVQFEATSPRYFFHEAINWGESKIKGSCPHECLNGAFCSKTGTCDCQIFQALGTRCQIVPNMGSGRDGICKTWGQYHFETFDGIYYYFPGSCSYIFAKDCGNLEPQYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIRKNGISLSLPQTLGQVHLEKVADYILVKTTFGFSLAWDGISGIYLKLSEEHRGKSCGLCANYNGIQSDDFVILQEDYTEDIAMFANSWLVLTPDDTKCVPTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRAATEYARACSHAGFPIQDWRDDFPACTDKCDDSFVHRDCISCCPPSCTFEKQCLGSNLHCLDGCYCADGLIMDNGTCISLESCPCSFHGLAYSVGSKIEQECTECVCVGGVWNCTEHDCPVQCSVVGDSHFTTFDGRHYSFIGLCQYILVKGTGKDRFTITLQKAHCEQNLGLVCLQSITLILEDDFNKQVTLSRGGQIVTSPNQGFTLNGIVEIQTLSSLFILLRTTFGLKILFAIDGERIYIQLSSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHAHAWRVSSTCFAPVHVPMVDPCNINQQNIGYAAHCDVIHQELFAPCHVYVSPGLYYQLCRHDACKCGSPCLCNALAHYAYLCGQRGVPIDFRAHISFCAVVCQKGMLYHHCSSLCLRSCTSLSSPEQCKDDCAEGCNCPEGKFYEETLNFCVPIYHCRCHYRGSIYQPGELIPTPSGLCQCSNGTVKCDELATPSTVHACPEGKEYFDCRFPDPALPAGGINCETTCANLAMNFTCAPSSPCISGCVCAAGMAEHKGKCYVPESCPCIWKDWEYSSGEVISTPCYTCVCRRGMFNCTYYPCPAVCTVYGDRHYHSFDGLEYDYISDCQVFLIKSTDDSDISVISQNKKCFDNDIVCSKSVLISIGDTEIYLNDAPYKQKRSGFFLESRPEYQLWKAGFYIVIYFPEEDITILWDEKTTIHIKVGPQWKNKLAGLCGNFDKCTSNDMTTSNNIEVRNAQVFGDSWALGQCEDLMEALKPCEAHQNKFPYAKRECSILYSDVFAPCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSVAAYAYKCCQEGVPVHWRSPTVCALDCEYYNQGLGEGPYMLASYGQSGLVLGANMTSRSVFSLPRSNNRGNLFFIFMITPGLFKEKTSSLALVSLESAERPNYFLYVHDNDTLSLKLWRANSEFHQRATFFHHQGLWIPGYSAFELYSKKGYFIVFMGSSVKASKYDDSEEFKQSSSFSIEEIQAVVPYRRMCEWRYEPCATPCFKTCSDPEALACTFLPPVEGCLPYCPKNMILDETTLKCVHPEDCIPLFPTEPALPPDITPSDMTPTPGLECEPQQFDPVYNCSQYICLNMEWTFYNWSLNCPKDLEMPDCGFRGWPVQVNTDICCPEWECPCRCSMLSELSIITFDGNSAALSSMASYILVRVPGEIVVVHIDKCSMNQNGHALKKPASFGRISGLCFKKLNVTTSIHKILINRVVRKVDVDSIVVPLPFSSHELFIEDSGTMYVITTPAGLIIKWAHLTGIIDIHFGPQFNLSSYTEGLCGICNDNPDDDLRMQNGTIITNMEDIELFIGSWEIEKSFEVTMRRPVRNCTEYDCSHCIELLNREGFIPCHDKVSPRDFCEKMWINYTYFWSYECDAISAYVALCNKFDICIQWRTPDYCPLSCPEGKEYQPCVRPCEARTCLNKWFYGHSSCLNLREDCVCKNGTILHRPDKTLCIPEQECVCTDREEHPRSAGEIWNGGIDECTLYKCLEDGNIIPIEPVCEEEPSPICERTAEVVIGIVDKLTCCSKKVCGCDMSLCDRTIPPCTNSQKLIVGYSALSCCPQYECECDTVRCPDISTPVCRDDQFVLQVRQGEPCCFYPSCVCKTCTEPTPQCTDGEFLTVNINTTHLCCPQYYCVCEPDLCPPPSLECAKDMNLVKENVSGQCCPNWRCECNCETLVMPTCDVGEFAAIDQNFQTDCGCVQYLCEKDDVCVFQEVSVLNPGQSLIKYLEEEFCYIIECLDEKDNYTDFHTLNVTMVNCSKDCDAHQIYIPSSSDYDCCGTCKNISCKFIMENGTSVIYEEGSTWHYNCSTYECVNTEEGATILNYSMVCPPFNETECKLNEGIVKLYNEGCCKICKREERICQKVIIKSIIKKQDCVSQSSISVASCDGKCPSATIYNINVESHLRFCKCCRENGVRNVTVPLHCSGNGTEVMYTLQEPIDCTCQWN
What are the official names of this protein?
Otogelin-like protein.
What is the protein family that this protein belongs to?
Belongs to the otogelin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_RHORT
Sequence: MPLHRVEALGEPQDRTGKTFSGRTNGPISSPLTDTERRMSIPQNPAPVNLVGLSREEIAALLRDMGEKPFRAKQLWHWVYHRGETDFSAMTTLGTPLRAKLAETCVVARPHVVREQRSEDGTRKWLLRFPDGNEAETVYIPEDDRGALCVSSQVGCTLTCRFCHTGTQLLVRNLTAHEIVGQFMAARDAYGEWPSPTDESRQLSNIVLMGMGEPLYNYDNVAKAIGILLDNEGIAVSRRRITLSTSGVVPMIRRCGAELGVNLAVSLHAARDEIRDEIMPINRKYPLAELMAACREYPGASNARRITFEYVMLKGVNDSEADARALIKLVEGVPCKFNLIPFNPWPGSGFECPPIRHIERFANILFEAGYTAPIRMPRGRDILAACGQLRSDSLRERASLHKARLAAGVADDHAPAAAPLADTPGAVA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHA_SALCH
Sequence: MALPIIIDCDPGHDDAIALVLALASPELEVKAITSSAGNQTPEKTLRNVLRMLTLLKRPDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSGTAVELMAKTLRESAQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRDIGNPISTIVAELLDFFFEYHKDEKWGFVGAPLHAPCTIAWLLKPEIFTTVERWVGVETKGKYTQGMTVVDYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: RS12_PSEPK
Sequence: MATINQLVRQPRKRSVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKGRNQGRSKYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NINAB_GALME
Sequence: MAVHQEKLYPNCDSGVWLRSCEEEVTEPLEGTITGEIPSWLQGSLLRNGPGSLKVGSMRFEHLFDSSALLHRFAINDGSVTYQCRFLQSNTFKKNRAAERIVVTEFGTRAVPDPCHTIFDRVAALFKPGESLSDNAMISLYPFGDEIYAFTEGPVIHRIDPETLDTLERRNLMDSVSLVNHTSHPHVMPNGDVYNLGMSIVQGRLKHVIVKFPYTEKGDMFAKAHIVANMSPRWPLHPAYMHTFGITENYFVIVEQPLSVSLLTMVKSQPSNEPLASSLHWYPNHETHIVLLSRRDGKEVKRYRTEPLFYLHIINAYEHDGVLVVDLCAYKDAKAIDAMYINAIETMQSNADYAEWFRGRPKRLELPLNATNCSRIEPRLLAQLGCETPRIHYDLYNGRPYRYFYAISSDVDAANPGTIIKVDTKTGETKTWCDTNCYPSEPIFVPAPGATEEDDGVILSALVWGGAGAHCRRVALLVLEARGLRELARATFCAPSPVPKCLHGWFLPRRTQL
What is the function of this protein?
Catalyzes the oxidative cleavage at the 15,15'-double bond of carotenoids and the simultaneous all-trans to 11-cis isomerization of one cleavage product.  Carotenoids like 11-cis retinal can promote visual pigment biogenesis in the dark.  Essential for the biosynthesis of the 3-hydroxyretinal chromophore of rhodopsin from zeaxanthin and for proper photoreceptor development.
What are the official names of this protein?
Carotenoid isomerooxygenase, Beta-carotene 15,15'-monooxygenase and retinoid isomerase, Beta-carotene dioxygenase and retinoid isomerase, Neither inactivation nor afterpotential mutant B.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: DPOL_MUHVS
Sequence: MDTCVETFFNPYLRRKPRRDWRRCEDNNKNFLQVVPRGVLYDGATGLIKVQSGMEPRMFYAEKEYVLNPDKPWPTLRTRGWCRGPYSDDVRFHTYDQVVNLVLADSDEQISPRWNSHVVPAGNVIRMFGATDEGVSVCVNVFGQKAYFYCERMQSEDLKNTVYDIADKVPEPCSPFSVSISPVTKSSFYGYGLGHIPNLYRLSFNNWNMCRKIGKRMLEEGRKVYELGVDPLARFLIDRKIPSFGWCLARRYSVRAAGYVSRAQLEIDCDVADILPIEEQSNWPFYRCLSFDIECMSGTGAFPAAENVDDIIIQISCVCFGVGEMVHHAYDVHADLSTPAVPENHLFTIGPCAPIPDVKIYTFPSEYEMLRGFFIFLSWYSPEFITGYNINGFDIKYILTRAEKLYKMDVGQFTKLRRGGRMFVFSPEKGKAGFGTSNTVKVFWSGTVVLDMYPVCTAKASSPNYKLDTMAEIYLKKKKDDLSYKEIPVQFSAGDEGRAPGGKYCLQDAVLVRELFEMLAFHFEAAAIARLARIPLRKVIFDGQQIRIYTCLLEECSGRDMILPNMPSLGHGAAAAIEEAAAGGEGDETSEGENSNNSRTVGYQGATVLEPECGFHHVPVCVFDFASLYPSIIMSNNLCYSTLLVEGSPEVPEKDVLRVEIGDQCHRFVRENVHRSLLAELLVRWLTQRKLVREAMKQCTNEMQRMIMDKQQLALKVTCNAFYGFTGVAAGMLPCLPIAASITKIGRDMLLATAGHIEDRCNRPDFLRTVLGLPPEAIDPEALRVKIIYGDTDSVFAAFYGIDKEALLKAVGALAANVTNALFKEPVRLEFEKMFVSLMMICKKRYIGKVHGSQNLSMKGVDLVRRTACGFVKAVVSDVLHMVFNDETVSEGTMKLSRMTFDDLKKNGIPCEFGPVVSRLCRARDDLHLKKVPVPELTLSSVLSQELSCYKQKNLPHLAVIRRLAARKEELPAVGDRVEYVLTLPDGCKKNVPNYEIAEDPRHVVEAKLSINAEKYYEQVVKAVTNTLMPVFPRDMPKREKFFSLVVPQRIYIPDQFLHLCGNVNELARGGDDSDGGDSEKENMDTERSSSHEAMET
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: DMRT3_HORSE
Sequence: MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAAAAAPQPPPTSQPSQPPPPQRPAAELAAAAALRWATEPQPGALQAQLAKPDLTEERLGDGSSADNTETFSDKDTDQRSSPDVVKSKGCFTPESPEVVSVDEGGYAVQKNGGTSESRPDSPKYHGEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSASAADRTSAEPESLVLPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPNPLAVPLQHPFPQPPRYPLMLRNTLARNQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPGSSPSVFRSSPVLPTRAPEDPRISIPDDGCPIVSKQSLYTEDDYDERSDSSDSRILNTSS
What is the function of this protein?
Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates.  Involved in neuronal specification within a specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements.  May regulate transcription during sexual development.
What are the official names of this protein?
Doublesex and mab-3 related transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.