PharMolix/UniProtQA huggingface dataset:
Protein: ZN598_DANRE
Sequence: MHCAERLRTEERASPGLIACTAVHKPSKSTRIKPTKPHHTPSNSMESALKKDTESTCVLCCQDIDLFAVGKCDHPVCYRCSTKMRVLCEQKYCAVCREQLDKVVFLRKPEAFATLNIHHYQCEKKYDIYFGDGKVHAQFRKILLNECPHCPEPKVFSKFEELEQHMRKQHELFCCKLCLKHLKIFSYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCDDRYLDNDELLKHLRRDHYFCHFCDADGAQEYYSDYQYLSEHFRESHYLCEEGRCSTEQFTHAFRTEIDYKAHKAAAHSKNRAEARQNRQIDIQFNYAPRQQRRNDVGGDDYEEVDRFNRQGRPGRGRGPGGQQNLRSWRYNREEEDREMAAAMRASMASHQEERSHAQERSMLKPRREEKLEPDETRNNRSTARPTNDTQARSMKSNGSLAGQDFPVLGAGAPPAPVQSMIQKPSVSLKEDDFPSLSGSVVSSPMTPAYTNQPRKHSSFQEEDFPALVSKIKPLKPQSSAASAWSQAGSKPVVAPNKPVVLPTKMTPMSSSSILSSTDPLPSASVPQPLTASSSRRKKMLTLTESHKDPPKIRCPSSSDDEDPHSGKTAQEIRTVPTMLDISTLLTVKGSSPQANPKASKKKKQTTASSLGSPSHTPETVSKMAHKENVPEKKPPETGLNKAPTAPKTNSIVNGVAEKPAEALSCTSFPENITSSKQPVTDQAPPSKEEEFPALISKKPPPGFKSAFPLRNSQSALPPPPPPGLGPAVSKPPPGFTGVPLNSNVEDSSVSAVNRPTPAIGSYLIPDHFQQRNMDLIQSIKNFLQNDETKFNEFKNYSGQFRQGALPAVQYYKSCQELLGENFNRVFNELLVLLPDTRKQQELLTAHGDFKALEKQQQGSKPKKSKKKAWQTGTSSSSSLDLDCQVCPTCKQVLALKDFNTHKTLHIGDDDFPSLQAISKIIS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation.  Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of a subset of 40S ribosomal subunits.  Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNF598, Zinc finger protein 598.
What is the protein family that this protein belongs to?
Belongs to the ZNF598 family.
Protein: ATPD_BURCM
Sequence: MAELATIARPYAEALFRVAEGGDIAAWSTLVQELAQVARLPEVLSVASSPKVTRTQVVELLLAAVKSPVAAGAEAKNFVQMLVDNHRIALLPEIAEQFEALKNEREGAADAEIVSAFPLNGADLESLVSGLERKFKRKLKPTVEVDSSLIGGVRVTVGDEVLDTSVRARLASMQAALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLPX_RUMCH
Sequence: MTRYDEKKQLKCSFCGKSQEQVKRLVAGPGVYICDECIELCSEIIEEEFEDTKIDAEVSEIPKPKEIKEILDQYVVGQDAAKRSLSVAVYNHYKRINSDVKTTDIELQKSNIVMLGPTGSGKTFLAQTLAKILNVPFAIADATSLTEAGYVGEDVENILLRLIQAADYDIEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTLASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIDKIIQNRIGKKSLGFGAKIESSKDKDVGQLLKDILPQDLLKFGLIPEFVGRLPIVVTLQSLDKKALVQILTEPKNALVKQYQKLFEMDDVLLEIQDEALEHIAEKAIERNTGARGLRAILEEAMLGVMYDIPSMTNVEKCIIGKEVIAEHSEPELILNENRKSLKKAGAKRTRVKKESVS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: TX1A_PHOKE
Sequence: AELKSCFPVGHECDDDASNCNCCGDDVYCACGWGRWNCKCKVADQSYAYGICKDKVNCPNRHLWPAKECKMPCRRNCG
What is the function of this protein?
Lethal neurotoxin.  Causes spastic paralysis and death in mice in 4-6 min after intracerebroventricular injection at dose levels of 1. 5 ug per mouse.
What are the official names of this protein?
U5-ctenitoxin-Pk1a, U5-CNTX-Pk1a, Neurotoxin PKTx15C1, Neurotoxin PKTx1A.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 02 (Tx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TBPB2_NEIMI
Sequence: MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVETVQDMHSKPKYEDEKSQPESQQDVSENSGAAYGFAVKLPRRNAHFNPKYKEKHKPLGSMDWKKLQRGEPNSFSERDELEKKRGSSELIESKWEDGQSRVVGYTNFTYVRSGYVYLNKNNIDIKNNIVLFGPDGYLYYKGKEPSKELPSEKITYKGTWDYVTDAMEKQRFEGLGSAAGGDKSGALSALEEGVLRNQAEASSGHTDFGMTSEFEVDFSDKTIKGTLYRNNRITQNNSENKQIKTTRYTIQATLHGNRFKGKALAADKGATNGSHPFISDSDSLEGGFYGPKGEELAGKFLSNDNKVAAVFGAKQKDKKDGENAAGPATETVIDAYRITGEEFKKEQIDSFGDVKKLLVDGVELSLLPSEGNKAAFQHEIEQNGVKATVCCSNLDYMSFGKLSKENKDDMFLQGVRTPVSDVAARTEANAKYRGTWYGYIANGTSWSGEASNQEGGNRAEFDVDFSTKKISGTLTAKDRTSPAFTITAMIKDNGFSGVAKTGENGFALDPQNTGNSHYTHIEATVSGGFYGKNAIEMGGSFSFPGNAPEGKQEKASVVFGAKRQQLVQ
What is the function of this protein?
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host.  Acts as a TF receptor and is required for TF utilization.  Involved in the initial capture of TF.  Helps select only those TF molecules that can be used as an iron source and concentrates them on the cell surface, maintaining the iron-loaded status of the TF C-terminal lobe until its delivery to TbpA.
What are the official names of this protein?
Transferrin-binding protein B, TbpB, Surface lipoprotein TbpB, Transferrin-binding protein 2, TBP-2.
What is the protein family that this protein belongs to?
Belongs to the TbpB family. Isotype I subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Cell surface.
Protein: RL19_CHLPM
Sequence: MDQLIQLVEATQAGVETPDIYPGDSVRIQLRVIEGEKERLQAFDGVVISDRGAGTNKTITVRKISHGVGVERIIPINSPNVESVTVLKHGKARRSKLFYLRKRTGKAALKVKERKVAEKAS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SALL2_MOUSE
Sequence: MSRRKQRRPQQLISDCEGPSASENGDASEEDHPQVCAKCCAQFSDPTEFLAHQNSCCTDPPVMVIIGGQENPSNSSASSAPRPEGHSRSQVMDTEHSNPPDSGSSGAPDPTWGPERRGEESSGQFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPPPPPPPPPGVGSGHLNIPLILEELRVLQQRQIHQMQMTEQICRQVLLLGSLGQTVGAPASPSELPGTGAASSTKPLLPLFSPIKPAQTGKTLASSSSSSSSSGAEPPKQAFFHLYHPLGSQHPFSVGGVGRSHKPTPAPSPALPGSTDQLIASPHLAFPGTTGLLAAQCLGAARGLEAAASPGLLKPKNGSGELGYGEVISSLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVITSSGLPYGMSVPPEKAEEEAGTPGGGVERKPLVASTTALSATESLTLLSTGTSTAVAPGLPTFNKFVLMKAVEPKSKADENTPPGSEGSAIAGVADSGSATRMQLSKLVTSLPSWALLTNHLKSTGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVASTASGAPTTSAPAPSSSASGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKTSPAARAQNSCPICQKKFTNAVTLQQHVRMHLGGQIPNGGSALSEGGGAAQENSSEQSTASGPGSFPQPQSQQPSPEEEMSEEEEEDEEEEEDVTDEDSLAGRGSESGGEKAISVRGDSEEVSGAEEEVATSVAAPTTVKEMDSNEKAPQHTLPPPPPPPDNLDHPQPMEQGTSDVSGAMEEEAKLEGTSSPMAALTQEGEGTSTPLVEELNLPEAMKKDPGESSGRKACEVCGQSFPTQTALEEHQKTHPKDGPLFTCVFCRQGFLDRATLKKHMLLAHHQVPPFAPHGPQNIATLSLVPGCSSSIPSPGLSPFPRKDDPTMP
What is the function of this protein?
Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure.
What are the official names of this protein?
Sal-like protein 2, Spalt-like protein 2, Zinc finger protein Spalt-2, Sal-2, mSal-2.
What is the protein family that this protein belongs to?
Belongs to the sal C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_PARD8
Sequence: MSSTAENQRVNFASIKNQFPYPDFLEVQLKSFQDFLQLDTPPEKRKKEGLYKVFAENFPIADTRNNFVLEFLDYYIDPPRYCIDECIARGLTYSVPLKAKLKLYCTDPDHEDFDTVIQDVYLGPIPYMTDRGTFVINGAERVVVSQLHRSPGVFFGQSTHANGTKLYSARIIPFKGSWIEFATDINNVMYAYIDRKKKLPVTTLLRAIGFESDRDILEIFNLAEEVKVTKANLKKFIGRKLAARVLKTWVEDFVDEDTGEVVSIERNDVIIDRESVLDSDNIEAILDSGTQNILLHREDQNLSDYAIIYNTLQKDPSNSEKEAVLYIYRQLRNAEPADEASAREVITNLFFSEKRYDLGEVGRYRINKKLGLTTSADVKVLTKEDIIEIIKYLIELINSKAIVDDIDHLSNRRVRTVGEQLYNQFGIGLARMSRTVRERMNVRDNEVFTPIDLINAKTISSVVNSFFGTNALSQFMDQTNPLAEITHKRRLSALGPGGLSRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLCVYAKINDLGFISTPYRKVADGKVDFSEEGLQYYTAEEEEELTIAQGNAPLDDNGKFIRDKVKARFEADFPVVPPSEIDLMDVAPQQIASIAASLIPFLEHDDANRALMGSNMMRQAVPLLRTDAPIVGTGIEAQVARDSRTQIMAEREGEVVFVDATCIKIKYDRTEDEEFVSFEDAVKTYNIPKWRKTNQSTTVDLKPTCHRGQRVKAGDILTEGYSTQKGELALGRNVKVAYMPWKGYNYEDAIVLNERMVREDFFTSVHVDEYILEVRETKRGMEELTSDIPNVSEEATKDLDERGIVRVGARIEPGDILIGKITPKGESDPSPEEKLLRAIFGDKAGDVKDASLKATPSLRGVVIETALFSKAVKKRKSRLTDKAILPKLDEEYEEKMASLKTLLVDKLLVLTNGKVSQGVKDYMNTEIIAKGAKFTRKSLEELDYNSIQVSKWTADAQKNELIKQVILNYLKKYKELDAELRRKKFDLTIGDELPTGIVQMAKVYIAKKRKIQVGDKMAGRHGNKGIVSKIVRQEDMPFLEDGTPVDICLNPLGVPSRMNLGQIFEAVLGWAGRELDVKFATPIFDGATLDDLNEWTDKAGIPRYGKSYLYDGGTGERFDQPATVGVTYFLKLGHMVDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAFGAAHVLQEILTIKSDDVVGRSKAYEAIVKGDPMPQPGIPESLNVLLHELRGLGLSFTLD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: YKY5_YEAS7
Sequence: MLECLSALLVLFAGGGGSVLAAVQSKTVADPNLCPGYNSQLISPFLSSCKRNLSECVSRYFDEQYAFCRSCVTVNNETMEDLDNCKCLQCALSSLNNSCFHDYCTSKDEYDKLQIVVEQFQLTNGVLDDGEILKPRGNKFSSRKLSYFVGQNNTLFRNPLQFEKNQLISALLTSLTNNQKTISSVDMFEVVDANNEVQYLRKRTISGKTLSPATGYEEENDGDCSVKDKKWEGKIEYHENKKVSSENCSKDTDDKSGSKKERNTKAPLFHTATEIHMTRWSSWRPKKIFTRYLVNEYQSPKIITTVNRFYRTKTDTETGTTLITSTKAKRRWFPRTKIVTSTATSTFLSITTTTTTNAIATKSLVAVLNPDGLNKKAGINFGLFSANGELASPDEGGTPTVVRRDKISDPGAANEQATLFSTTFSQVPHLPELDSGEFISAASQLDKRIFIFTAITVSITTLMMLGFSYRSRVSFRDHSIDDSDDDNDWSDDEVEFDEEYFYSLPVSIPEKGISLDKMAQQLGVE
What are the official names of this protein?
Uncharacterized protein SCY_3380.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RECF_STRS2
Sequence: MWLERLELQHFRNYNQLDIEFHKGLNVFLGENAQGKTNILESIYVLALTRSHRTRTDKDLLQFQEKELSISGLLHRTSGKVPLDIHLTDKGRVTKVNHLKQAKLSNYIGHMNVVLFAPEDLQLIKGAPALRRKFIDVELGQIKPLYLSDLSNYNHVLKQRNTYLKSTDKIDENFLSVLDQQLAEYGSRVIQHRIDFLKKLEEFGNRKVQEISGNREELTIEYQTSIELTDDVNLIDKFLTELEKSRKRDLFKKNTGVGPHRDDVAFFINGMNAHYASQGQHRSLVLSLKLAEIELMKEVTREYPILLLDDVMSELDNNRQIKLLETITDTIQTFITTTSLDHLHKLPDSLKIFHIESGKVTESE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_LEGPC
Sequence: MSDLLGILKQQGQSEEFDAIKIALASPELIRSWSYGEVKKPETINYRTFKPERDGLFCAKTFGPVKDYECLCGKYKRLKHRGVICEKCGVELALAKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFEAFVVVDPGMTELERGQLLNDEAYLDAMEQYGDEFDARMGAEAIRDLLRQIDLEDEIRNLREELPTTNSETKIKKITKRLKLLEAFYESGNKPEWMIMDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFSKLEFRGLATTIKAAKKMVEREESVVWDILDDVIREHPILLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAYNADFDGDQMAVHVPLTLEAQLEARSLMMSTNNILSPASGEPIIVPSQDVVLGLYYLTREKVNALGEGKIYSSAQEAQNFYEAGHLDIHAKIKIRMPKEDGETGYHLVETTVGRAILAEILPKGMPFDYINRTMTKKVISKVIDSCYRKFGLKETVIFADQLMYTGFKYATRSGASIGIEDMEIPDDKASIIEHADNEVREIESQFRSGLVTNGERYNKVIDIWSRTNELVAKSMMSKIATEEVTDAKGNKVRQESFNPIFMMADSGARGSAAQIRQLAGMRGLMAAPDGSIIETPITANFREGLNVFQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITEDDCGTDTGILMQPLIEGGDIVEPLHERVLGRVVASDVYIPTQTEPVVKAGTLLDEEWVEKLEKHGVDQVMVRSPITCQTRFGLCAKCYGRDLARGHLVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGAASRATAANNIQIKTKGVIRLHNIKTVTHENKNLVAVSRSGEVTIVDEFGRERERYKVPYGAVISAQDNSPVEAGQVIATWDPHTHPVISEVSGRLKFVDLIDGITMNRQTDELTGLSNIVIIDAKQRSAAGRDLRPMVKLVTDEGDDIYLAGTNVPAQYYLPVDAIVNFEDGSLVGIGDVIARIPQERSKTRDITGGLPRVADLFEARKPKDSAVMAEVSGLVNFGKETKGKRRLIINVSEDQCHEELIPKWRHISVFEGEHVERGEIIAEGALNPHDILRLLGVGALANYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKRVITFAGDSKFLVGEQVEESAMLQENDKLLAEGKQIARGTPILLGITKASLATESFISAASFQETTRVLTEAAVSGKVDELRGLKENVMVGRLIPAGTGYTYHQSRKAKRARAAAGGDSSATHTVTASDVEHALSEALNADNHEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: APBE_HAEIN
Sequence: MKKLISGIIAVAMALSLAACQKETKVISLSGKTMGTTYHVKYLDDGSITATSEKTHEEIEAILKDVNAKMSTYKKDSELSRFNQNTQVNTPIEISADFAKVLAEAIRLNKVTEGALDVTVGPVVNLWGFGPEKRPEKQPTPEQLAERQAWVGIDKITLDTNKEKATLSKALPQVYVDLSSIAKGFGVDQVAEKLEQLNAQNYMVEIGGEIRAKGKNIEGKPWQIAIEKPTTTGERAVEAVIGLNNMGMASSGDYRIYFEENGKRFAHEIDPKTGYPIQHHLASITVLAPTSMTADGLSTGLFVLGEDKALEVAEKNNLAVYLIIRTDNGFVTKSSSAFKKLTETKE
What is the function of this protein?
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein such as NqrB and NqrC, two subunits of the NQR complex.
What are the official names of this protein?
FAD:protein FMN transferase, Flavin transferase.
What is the protein family that this protein belongs to?
Belongs to the ApbE family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side.
Protein: MENG_LEPIN
Sequence: MSGFQMPQANFKAGFVRENFNKIAKKYDRFNDWNSFLLHRVWKNHLVREIENNFSGHLHVLDLCCGTGDISLRLENSSFVDHVTCVDFSENMLEIAKTRLKKQAQKGRVHFELGDATKLIQFQNSQFDVVSIGFGLRNVDNLSKAIGEIFRVLKPGGMFLNLDVGKVKNPWIRWIADFYFFKIVPILGYILWGGKNEMFDYLPVSSLSYPDQETLQLILEKEGFQRVQYKNFVFGNVVLHVAKKPSEKT
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RBL_NITEC
Sequence: MAIKTYQAGVKEYRQTYWQPDYVPLDTDILACFKITPQSGVDREEAAAAVAAESSCGTWTTVWTDLLTDLDYYKGRAYRIEDVPGDDARFYAFVAYPIDLFEEGSVVNVFTSLVGNVFGFKAIRALRLEDVRFPIAYVKTCGGPPSGIQVERDKMNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGSLDFTKDDENINSQPFMRWRDRFEFVQEATLKAEAETGERKGHYLNVTAPTPEEMYKRAEFAKEIGAPIIMHDYLAGGLCANAGLANWCRNNGMLLHVHRAMHAVLDRNPHHGIHFRVLTKILRLSGGDHLHTGTVVGKLEGDRASTLGWIDLLRESFVPEDRSRGIFFDQDWGSMPGAFAVASGGIHVWHMPALVAIFGDDSVLQFGGGTLGHPWGNAAGAHANRVALEACVQARNEGRQIEKEGREILTAAAQHSPELKIAMETWKEIKFEFDTVDKLDIAHK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: Y388_ACTP7
Sequence: MSLQFNPISLFLVVLIFLGVVGNNNSITIAATVLLLVQQTFLSKYLPFLDKHGLSIGIIILTIGVLSPIVSGKISLPSFSEFLNWKMLLAVVAGIAVAWLGGRGVSLMGGQPLLVTGLLVGTIIGVALLGGVPVGPLIAAGILSLLIGKG
What are the official names of this protein?
UPF0756 membrane protein APP7_0388.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRAA_HUMAN
Sequence: MRNSYRFLASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV
What is the function of this protein?
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse (PubMed:3257574, PubMed:3262682, PubMed:3263427, PubMed:32299851, PubMed:12819770).  It cleaves after Lys or Arg (PubMed:32299851, PubMed:12819770).  Once delivered into the target cell, acts by catalyzing cleavage of gasdermin-B (GSDMB), releasing the pore-forming moiety of GSDMB, thereby triggering pyroptosis and target cell death (PubMed:32299851, PubMed:34022140, PubMed:36157507).  Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity (PubMed:12524539).  Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (PubMed:11555662, PubMed:12628186, PubMed:16818237).
What are the official names of this protein?
Granzyme A, CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor, H factor, HF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
[Isoform alpha]: Secreted. Cytoplasmic granule. Note=Delivered into the target cell by perforin.
Protein: GREA_XYLFA
Sequence: MRAPMTLKGVRRLRDELEHLKSVKRPEIINAIAEARAHGDLKENAEYHAAREQQSFIEGRIKQLEGELSHAEVIDVAKLNAGTKIVFGATVTLVDLETDEESRYQIVGDLEADIKQGLVAISSPVARALIGKQEGDTIVIEAPAGRREYEVVAVEYIS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MURA_SULNB
Sequence: MQYLEIKGGKKLSGSVTISGAKNAALPVIAATILSDKDVTLTNLPNVVDIRTLLKLLTMLGGVVEHEGTVAKINNGSITSTKAVYEIVSQMRASILVLGPLLTRFGECEVSLPGGCAIGQRPIDLHLKALEAMGAKITIESGYVHAVAPNGLHGAKIIFDKITVGGTENIIMAAALAKGTTIIINAAKEPEIVQLCEMIADAGVKIEGIGTNELTIEGTDGIPLAFKTVEIIPDRIEAGTYLCAGAITKSEITLNKVNAEHIRASIDKLESMGFTFDIAKDSITIHPTDIINPVNLITIEYPGFPTDMQAQFMAVAAMADGESLIEERLFENRFMHVSELNRLGADIWLKGSVAAVKGVKELHGADVMATDLRASSALVLAGLVAEGTTNVRRIYHLDRGYDNLEGKLAALGADIVRKEEEK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_POLSJ
Sequence: MKPVIALVGRPNVGKSTIFNRLTKTRDAIVADFAGLTRDRHYGNGKLGSHEYIVIDTGGFEPDAASGIYKEMAKQTRQAVAEADVVIFVVDARAGISAQDHDIANFLRKLGKPTVLTANKAEGMTEGVQFSEFFELGLGEVLPVSASHGQGMRSLVDLALAPLHLADPDEEAEPQDPSVIRLAVAGRPNVGKSTLINTWLGEERLVSFDLPGTTRDAISVPFERAGQKFELIDTAGLRRKGKVFEAIEKFSVVKTLQAIEGANVVLLLLDATQGVTDQDAHIAGYILESGRAVVLAINKWDAVDAYQRETLERSIETRLAFLKFASIHKISAIKRQGLAPVWKSIVQAHASANRKMSTPVLTRLLLEAVQFQQPQRSGMFRPKMRYAHQGGMNPPIIIIHGNSLEHVTEAYKRYLEGRFRKEFDLVGTPMRIQMKSSHNPFTDKDSA
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MLTC_KLEP7
Sequence: MKKYLALALIAPLLVSCSSSNKKGAEYNEAWVKDTNGFDILMGQFAHNIENIWGYNEVLLAGPKDYVKYTDQYQTRSHINFDEGTITVETIAGTDPRGRLRQAIVKTLLMGDDPNSIDLYSDVDDIQISKEPFLYGQVVDNTGASIRWEWRAARFADYLLQTRLKSRNNGLRVVYSITINLVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSHADAMGLMQVVQHSAGRDVFRSQGKSGLPSRSYLFDPANNIDTGTAYLAMLNNVYLAGIDNPTSRRYAVITAYNGGAGSVLRVFSSDKVQAANIINSMAPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRK
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CYF_OENEH
Sequence: MKNTFSWIKKEITRSISLSLMIYIITRTSISNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDRQVKQVLANGKKGGLNVGAVLILPEGFELAPPARISPEMKERIGNPSFQSYRPTKKNILVIGPVPGQKYSEITFPILSPDPATNKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAAGIVSKIIRKEKGGYEITITDASDGRQVVDIIPSGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEVVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DB132_MACFA
Sequence: MKFLLLVLAALGFLTQVIPASGGGSKCVSDTPGYCRTHCHRGETALFMCSPFRKCCISYSFLPQPDLPQLIGNHWPSRSRNTQRKNKKQQTTVTP
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 132, Defensin, beta 132.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYCH_CLITE
Sequence: GLPCGESCVFIPCITTVVGCSCKNKVCYND
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide cter-H.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RL17_PSYCK
Sequence: MRHRKSGVKLGRTGSHRKAMFQNMTNSLFEHELIKTTLPKAKELRRVAEPLITMAKEDSVANRRLAFSRMRSKAMVGKLFGTLGPRYQARPGGYLRIVKCGYRDGDNAPMAYVELVDRD
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.