PharMolix/UniProtQA huggingface dataset:
Protein: RHAT_KLEP7
Sequence: MNHAITMGIFWHLIGAASAACFYAPFKKVKHWSWETMWSVGGIVSWLILPWAISATLLPDFWAYYRSFSASTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGQFAVLMHTQGGQMTLLGVLVAVIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHDAAAALGVDPLYAALPSYVVIMGGGALVNLGFCFIRLAKVKNLSVKADFSLAKPLIISNLLLSALGGLMWYLQFFFYAWGHASIPAQYDYMSWMLHMSFYVLCGGVVGLVLKEWNNAGRRPVSVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13_NEIMB
Sequence: MKTFSAKPHEVKREWFVIDAQDKVLGRVAAEVASRLRGKHKPEYTPHVDTGDYIIVINADKLRVTGAKFEDKKYFRHSGFPGGIYERTFREMQEQFPGRALEQAVKGMLPKGPLGYAMIKKLKVYAGAEHAHAAQQPKVLELK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ADT3_BOVIN
Sequence: MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKSGSEREFRGLGDCLVKITKSDGIRGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYKGTVDCWRKILKDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (By similarity).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis.  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A6/ANT3 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (By similarity).  It is however unclear if SLC25A6/ANT3 constitutes a pore-forming component of mPTP or regulates it (By similarity).
What are the official names of this protein?
ADP/ATP translocase 3, ADP,ATP carrier protein 3, ADP,ATP carrier protein, isoform T2, ANT 2, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6/ANT3 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (By similarity).
Protein: RNH_RICBR
Sequence: MKEDISKVVIYTDGACSGNPGPGGWGALLQFNEVNKEIFGHELETTNNRMEITAALEALKILKKPCHVEIYTDSKYLQQGITVWIHNWIKNNWCKSNNEPVKNADLWQNLYEELSKHTIIWKWVKGHASNSGNIAADKLAVQGRQTAIEILKCRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_SMAMI
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: LON_SYNWW
Sequence: MPTEEHQTYRELPMLPLRGVLVFPYTVIHLDVGRKKSINAIEDAMLGSKEIFLATQKEAQTDEPDEEDIYEVGTVAEIRQILKMPGGTMRVLVEGLFRAEINAYLANDPYMKVRVEELRDKKIKSPELEALMRNLVGQFEQYVRMSKKIPPETVVSVVAIEEGGRLADVIASHLNLRINEKQRILELSDINKRLNYLCELLAKEMEVLELERKINIRVRKQMEKTQKEYYLREQIKAIQKELGEKDERSSEVEEFRERIKKANMPKDAEEKAFKELERLEKMPPMVAEAVVVRNYLDWILSLPWSLETRDRLDLKAAEAILDEDHYGLEKPKERILEYLAIRKLAKKMKGPILCLVGPPGVGKTSLGKSVGRSLGRKFIRMSLGGIRDEAEIRGHRRTYVGSMPGRILQGMKTAGSKNPVFLLDEIDKMTMDFRGDPASALLEVLDPEQNYIFSDHYLEIPFDLSKVMFITTANSVFNIPRPLLDRMEIIEITGYTEEDKVHIATDYLVPKQIKEHGLKESNITFSEGTLRRIIREYTREAGVRNLERQIASICRKVARQVVEDKDTFVHVASNSLNRFLGAGRYRYGVAESENQVGVATGLAWTESGGDILSIEVALLKGKGNLTLTGKLGEVMKESAQAALTYVRSKADELGINDEIRDKYDVHIHIPEGAIPKDGPSAGITLATALASAMSGLPVRSDVAMTGEITLRGRILPIGGVKEKILAAHRAGIAKVLLPVENKKDLAEIPAPVKRKIKLVLVSHMDEVLEETLLKLEAIQPGEDFPGVLLNPELVGENLNQDRVEPEANKDLC
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_SHEB5
Sequence: MNIRPLHDRVIVKRLEVESTSAGGIVLTGSAAEKSTRGEILAVGNGRILENGTVKPLDVKVGDVVIFNEGYGVKKEKIDGQEVLILSEADLMAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPGS_METS3
Sequence: MKSISKMLCLVDGEHYLPVTQESIDVLNNLEHIDIVAAVFIGGTEKLRDDSEESYSKVLGVPVQFAKNEDIPYDIIVEMINRYDVDTVMDLSDEPILDYPKRFKIACKTLAQGVSYQGPDFKFDPVTQYEIMEKPSIKIIGTGKRIGKTAVSGFVSRLIDKNGYEPCVIAMGRGGPQEPEIVHGEQLEITPEFLLEQSEKGVHAASDHWEDALMSRILTIGCRRCGGGMAGEVFLTNMKKGAKLANQVDSKFAIFEGSGAAIPPIKTNKNIVLIGANQPLNNIIDYFGPYRIGLGDLIILTMCEEPMCNEEKREYIEKFIKEINPKAKIISTVFRPKPLADISGKKVLFATTAPKSIEHELVDYLETNYNCEIVGTTPHLSNRPLLKKDIEKYMDEADIMLTELKAAAVDVATKDSIKAGLDVVYCDNIPVPINYKYPDLSKSVLEIVDEAIEDFNKD
What is the function of this protein?
Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
What are the official names of this protein?
Cyclic 2,3-diphosphoglycerate synthetase, cDPGS.
What is the protein family that this protein belongs to?
Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEU1_ONCMA
Sequence: MFGTSVSALCLLFLLSVCTACYISNCPIGGKRSALAFPSRKCMSCGPGDRGRCFGPNICCGEGMGCYVGSPEAAGCVEENYLPSPCEVGGRVCGSEEGRCAAPGICCDVEGCSIDQSCTEEDEAEYISQSVSSSHGHDLLMKLLNMISHTPPHRVHK
What is the function of this protein?
Isotocin causes contraction of smooth muscles.
What are the official names of this protein?
Isotocin-neurophysin IT 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEPE_ECO7I
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ALIB4
Sequence: MATRTQARESVIGLLYAYDLGNDGITKFVDEILEEKKIRNNQKDFALNLFNGTIKNLSQIDENIVSNLNQGTLSDIGSVEKSILRLAIYEILFESLPKAIIINEAIELSKRLASDGAPKFINGLLDKIVKA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NUON2_STRGG
Sequence: MTADLGTTADLSTAPATGGLLAADAPSVVQSIDWLAVAPPTLTALAALAVLVADLFLPAHRKRLLGYAALTALAAALALLIPLRAGDRATFCVTTGTRACSYTADHFTLVIQALVLGGALLTVLLSLDDTRKLPAGEYWFLLLASAAGAALLPASRDLATLVVALEVASLPAFALVGIKRGDRRSSEAALKFFLSSVVATAVMLLGVSFVYATTGTLHLTEIATRLDDVPPVLDTLARTGVALTLVGFAFKTAAAPFHFWVPDTYVGAPLPIAAYLSVVGKAVGFSGLILVTVVAFPSYADVWGPALAVLAALTMTAGNVAALRQNAARARSAVRLLAWSSVAQAGYLLVPIAAAAYSSDDQIGSTVAYALMYAVVNLGAFAVAAVVARTHPGNRLTDYRGLYATRPLAALALGFFLLCLAGLPPGIIGLFAKVTVFSAAVDAGLGWLAVVMAVNVVIALYYYLQWTAILFRAPEGAPETTGTATAPTASAPPRRFRAPTPLTTAIVLTATAGILLSGVPQTVLRFASVSLF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 2, NADH dehydrogenase I subunit N 2, NDH-1 subunit N 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LAMB2_AERS4
Sequence: MKMKAKWLPIAAAVTAALASQAAFAVDFHGYFRSGVGVSTDGSMQTGLSDNAKQKVGRLGNEADTYGEIQLGSEVFNKDGKTFYVDSMVAMTSNGSNDWESTESKFQCTSANGTALDGCENKEDATFALRQFNVQAKGLLGFAPEATLWAGKRYYQRHDVHISDFYYWNISGAGAGIEGIQAGPGKVSFAWVRNDRSGTNDGWTYNDEMNVNTLDLRYAGIPLWQDGSLEVGVDYAIANPSDAQKDSANAQYKNAKDGVMLTAELTQGILGGFNKTVLQYGTEGYSKTFAFWGDGSWYGAEAKDGADGFRIINHGVIPMGNSWEMGHQLVYGVGNDMWDTNDKWETMSVVARPMYKWDDFNKTIFEGGYFKDKNKSTNGTSEEDAGYKLTLAQAWSAGSSFWARPEIRVFASYLAQDKKEMKGNAFNNGTADDTWNFGVQAEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 2, Maltose-inducible porin 2.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RF3_DESPS
Sequence: MSKQLEQEIAKRRTFGIISHPDAGKTTLTEKLLLFGGAINMAGAVKSRKIERKATSDWMAIEQERGISVTTSVMKFTYREHEINLLDTPGHQDFSEDTYRVLTAVDSAIMVIDSAKGVEAQTEKLMEVCRMRNTPIITFINKLDREGMHPLDIMADIEDKLQIECAPLSWPIGMGKDFKGVYNIYQKRLHLFTPGTESIDGQGQMIEDLDDPLLDELLGRQAVELREDLELLAGAATPLEYDQYLSATQSPVFFGSAVNNFGVQEMLDAFIDMAPAPGPRMAVSREVLPSEENFSGFVFKIQANMDPAHRDRIAFFRICSGKFTRGMKVHHHRLGKDISLANATIFMAQERANVEEAWPGDIIGIHNHGTIKIGDTFSIKEPLKFTGIPNFAPEHFRRVILKNPLKMKQLQKGLIQLAEEGAIQVFRPIIGADYIMGAVGVLQFEVTMARLKNEYSVDAIYEPISYQAARWVSCEDKKALAEFEKKNQSTLARDSEGFLTHLAQSDWMLNFFMEKWPNIDFHKTRENI
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIPKQ_ARATH
Sequence: MNRPKVQRRVGKYEVGKTLGQGTFAKVRCAVNTETGERVALKILDKEKVLKHKMAEQIRREICTMKLINHPNVVRLYEVLASKTKIYIVLEFGTGGELFDKIVHDGRLKEENARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDAQGNLKVSDFGLSALSRQVRGDGLLHTACGTPNYAAPEVLNDQGYDGATADLWSCGVILFVLLAGYLPFEDSNLMTLYKKIIAGEYHCPPWLSPGAKNLIVRILDPNPMTRITIPEVLGDAWFKKNYKPAVFEEKEEANLDDVDAVFKDSEEHHVTEKKEEQPTSMNAFELISMSRALDLGNLFEEEEGFKRETRFAAKGAANDLVQKIEEASKPLGFDIQKKNYKMRLENVTAGRKGNLRVATEIFQVSPSLHMIEVRKTKGDTLEFHKFYKKLSTSLNDVVWKSGESSGLSK
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.  Involved in the calcium-dependent regulation of reactive oxygen species production by the NADPH oxidase RBOHF.
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 26, SNF1-related kinase 3.26, SOS2-like protein kinase PKS26.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: BIOF1_BACSU
Sequence: MTKEFEFLKAELNSMKENHTWQDIKQLESMQGPSVTVNHQKVIQLSSNNYLGFTSHPRLINAAQEAVQQYGAGTGSVRTIAGTFTMHQELEKKLAAFKKTEAALVFQSGFTTNQGVLSSILSKEDIVISDELNHASIIDGIRLTKADKKVYQHVNMSDLERVLRKSMNYRMRLIVTDGVFSMDGNIAPLPDIVELAEKYDAFVMVDDAHASGVLGENGRGTVNHFGLDGRVHIQVGTLSKAIGVLGGYAAGSKVLIDYLRHKGRPFLFSTSHPPAVTAACMEAIDVLLEEPEHMERLWENTAYFKAMLVKMGLTLTKSETPILPILIGDEGVAKQFSDQLLSRGVFAQSIVFPTVAKGKARIRTIITAEHTKDELDQALDVIEKTAKELQLL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase 1, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MNTR_BACC1
Sequence: MPTPSMEDYIEQIYLLIDEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLIYEKYRGLVLTSKGKKIGERLVYRHELLEQFMRIIGVDESKIYNDVEGIEHHLSWEAIDRIGDLVQYFEQDEVRVETLRGVQKANEEKSN
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_BURMA
Sequence: MSQAIPQVGVHSEVGKLRKVLVCSPGLAHQRLTPSNCDELLFDDVMWVNQAKRDHFDFVSKMRERGVEVLEMHNLLTETVQNPAALKWILDRKITPDNVGIGLVDEVRAWLEGLEPRALAEFLIGGVAASDIAGAERSKVLTLFRDYLGKSSFVLPPLPNMMFTRDTSCWIYGGVTLNPMHWPARRQETLLVAAVYKFHPAFTDAKFDVWYGDPDRDHGMATLEGGDVMPIGRGVVLVGMGERTSRQAVGQLAQALFAKGAAERVIVAGLPNSRASMHLDTVFSFCDRDLVTVFPEVVNRIVPFTLRPGGDARYGIDIEREDKPFVDVVAQALGLKSLRVVETGGNDFAAEREQWDDGNNMVCIEPGVVVGYDRNTYTNTLLRKAGVEVITIGSSELGRGRGGGHCMTCPVLRDPVDY
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRR_STAXY
Sequence: MKNIADIAKIAGVSKSTVSRYLNNGSVSLKTQQKLDEIIRENDYQPNQFAQSLRARRTNMIGAIIPRMNSFAVDETIKGVKTVCDQLNYSLLLNYTNLNIQLEIDALETFYRSKVDGIVFMATEITDQHLEVINKINVPVIIVGQAHDDLHCIIHNDYQAGYLVGDMLGQQGYNDIKFFGVTESDIAVGVQRKEGLIAGLEAHNIQPEISLTSFNYQEAMVDVVEALQAYPHYDAIVGATDSIALAIHKYNSEHKPHAHEKYIVGFGGDPVTDIVSPSIHTINYNFEYAGSVAMDKLNQMIQHQVIEQRIIIDVEQSFEN
What is the function of this protein?
Negative regulator of scrB expression.
What are the official names of this protein?
Sucrose operon repressor, Scr operon regulatory protein.
Protein: SECA_VIBA3
Sequence: MITKLLTKVIGSRNDRTLRRLRKIVKEINNFEPTFEALSDDELKAKTVEFRERLDKGESLDQLLPEAFATVREASKRVYGMRHFDVQMIGGMVLNAGQIAEMRTGEGKTLTATLPAYLNALPSKGVHVITVNDYLAKRDAETNRPLFEFLGMTVGVNVANMAPPEKKEAYQADILYGTNNEFGFDYLRDNMAFRAEDRVQRERFFAVVDEVDSILIDEARTPLIISGPAEDSSDLYTRINTLIPSLERQDKEDSEEYRGEGHYTMDEKSKQVHLTENGQEFVEELMVKNGLMEEGDTLYSPTNISLLHHVNAALRAHVLFEKNVDYIVTEEGEVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNFFRLYEKLSGMTGTADTEAFEFQSIYGLETVVIPTNKPMVRNDMPDVVYRTEEDKFNAIIEDIKDRVAAGQPSLVGTVSIEKSELLSNALKKSKIKHNVLNAKFHEMEAEIVAQAGMPGAVTIATNMAGRGTDIVLGGSWQAQLEKLDNPTKEQIEKIKADWRIIHDKVLESGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLLRIFTSDRMAGLIQSGMDEGEAIESKMLSRSIEKAQRKVEGRNFDIRKQLLEYDDVANDQRKVVYELRDELMSSDDISEMIEHNREDVLASVIDEYIAPQSLEDMWDIAGLQDRLKNDFDLDFDIQGWLDEDDKLYEEALRERILGMAVDSYKQKEEVVGAQVLRNFEKSVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEGLLDVLKTDVVTILSKVRVQQQEEVEKMEAQRQAQAEQAARRAQAQHATAENQLADDEAEAASPQTVVRDERKVGRNEPCPCGSGKKYKQCHGKID
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS5_RICPU
Sequence: MSKVKKNDEILSEVLVDVNRVTKVVKGGRSFAFSAYVVVGDKAGRVGAGHGKAKEVNEARGKAKQAAKKRMMKVPLYQNRTIHHDVVGKSGAAKVILRRAKAGTGVIAGGSMRAIFDSLGVHDIVAKSIGSTNVYAMISATFDALNKLASPKSIAMRRDKKVNEISVKSADIQVNE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KAT3_DANRE
Sequence: MHPIHLLRIVSSVRRLLQTNRCRSFSSCQHNMASIKHKNARRIEGLDKNVWVAFTSVAADPSIVNLGQGYPDIPPPSYVKEGLAQAAMVDRLNQYTRGFGHPTLVKALSKVYGKVYDRQLDPFKEILVTVGGYGSLFSTMQALVEEGDEVIIIEPFFDCYVPMVKMAGAKPVLIPLRLKSTATTGISSADWVLDQEELASKFNSKTKAIIVNTPNNPIGKIFSRSELQAIADLCIKHDTLCFSDEVYEWLIYKGHEHVKIATLPGMWDRTITVGSAGKTFSVTGWKLGWSIGPEHLIRHLQTVMQNSLYTCPTPLQEAVGRGLLRDFELMGQPDCYFSALALELEGKRDRMAAMLAQTGMTPVVPEGGYFMIVDVTALNQDLTHMGDDEPYDYKFVKWMIKEKKLAAIPVTAFVGEDSVKQFEKYIRLCFIKQESTLDAAEAILKNWNKG
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others.  May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
What are the official names of this protein?
Kynurenine--oxoglutarate transaminase 3, Cysteine-S-conjugate beta-lyase 2, Kynurenine aminotransferase 3, Kynurenine aminotransferase III, KATIII, Kynurenine--glyoxylate transaminase, Kynurenine--oxoglutarate transaminase III.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: UPPP_LACLS
Sequence: MDFIRAIILGIIEGITEWLPISSTGHLIIADEFIRLNQSAAFKEMFDVVIQLGAILSVVVLYFHKLNPFNKLNPADKQKTPREIQLTWRLWLKVLIAALPAAIIGLPLNDWLDKHFYHFVPVAFMLIIYGVAFIVIERRWVPNHEFSVMDIDRLPYRAALYIGLFQVLSLLPGTSRSGATIVGALLIGVSREVAAEFTFFLGIPVMFGASFIKILHFFKNGNSLNLEQFGVLLVACLVAFGVSMIAIKFLTDYVKKHDFTFFGKYRIVLGIVLLIYAAFKAFLG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCM10_YEAST
Sequence: MNDPREILAVDPYNNITSDEEDEQAIARELEFMERKRQALVERLKRKQEFKKPQDPNFEAIEVPQSPTKNRVKVGSHNATQQGTKFEGSNINEVRLSQLQQQPKPPASTTTYFMEKFQNAKKNEDKQIAKFESMMNARVHTFSTDEKKYVPIITNELESFSNLWVKKRYIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPVKFFMFTITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWRPSGRGNFIKSFNLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAKRIELNGGYALGAPTKVDSQPSLYKAKGENGFNIIKGTRKRLSEEEERLKKSSHNFTNSNSAKAFFDEKFQNPDMLANLDNKRRKIIETKKSTALSRELGKIMRRRESSGLEDKSVGERQKMKRTTESALQTGLIQRLGFDPTHGKISQVLKSSVSGSEPKNNLLGKKKTVINDLLHYKKEKVILAPSKNEWFKKRSHREEVWQKHFGSKETKETSDGSASDLEII
What is the function of this protein?
Required for DNA synthesis.  Required for entry into or completion of S phase.  Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation.  May play a role as a key coordinator in assembling the replication fork.  Proposed to function at replication origins following the binding of the MCM2-7 complex prior to the recruitment of CDC45.  Probably is required to stimulate phosphorylation of the MCM2-7 complex by the CDC7-DBF4 kinase complex.  May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of CDC45.  May also play a role in transcriptional silencing.
What are the official names of this protein?
Minichromosome maintenance protein 10, Protein DNA43.
What is the protein family that this protein belongs to?
Belongs to the MCM10 family.