PharMolix/UniProtQA huggingface dataset:
Protein: NUDI_SALNS
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: CBL_CORST
Sequence: MQFSNLDTLRTRGTRKWTQFDDDVIPMFVAESDFPTAPAIKEAIIDACEREMFGYTPAPHAHHLGEAVADFYDWRYGWRPDAAKIFPVADVVRGVLLAIQYFTDGDVIVPVPAYFPFLPIAEAAGRNRIDISSDKGLEGGLDMAEVEEAFKNGAGSIIVTNPFNPGGWMFTSEELDQICDIARRYKGRVLVDEIHAPLTYGKRHVCAAANNPDVCITVTATSKAWNVAGLKCAQMIFTNDEDVKTWNAINPVAKDGVGTLGIIAAEAAYESGREHLDWQVEQLKANRDWLVENLPSLIPGIRFEIPDATYLMFLDFKDTKLGVDKPAAYLLKHARVALSEGVDFGPGGEHRARMNFATSPEILKEATERIARAIEVV
What is the function of this protein?
Catalyzes the cleavage of the cysteine-S bond in various cysteine-S-conjugates (PubMed:17191898, PubMed:18515361).  Cleaves L-cystathionine, as well as S-substituted cysteine conjugates S-benzyl-L-cysteine and S-ethyl-L-cysteine (PubMed:17191898).  Releases four human body odoriferous sulfanylalkanols: 3-methyl-3-sulfanylhexan-1-ol (3M3SH), 3-sulfanylhexan-1-ol, 2-methyl-3-sulfanylbutan-1-ol and 3-sulfanylpentan-1-ol; the release is obtained after the sequential hydrolysis of the Cys-Gly bond of the odorless Cys-Gly-S-conjugate precursors by the dipeptidase TpdA, then the cleavage of the resulting Cys-S-conjugates by MetC (PubMed:17191898, PubMed:18515361).
What are the official names of this protein?
Cysteine-S-conjugate beta-lyase, C-S lyase, Cystathionine beta-lyase, CBL.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
Protein: CINA_CLOBL
Sequence: MKAEILCVGTELLLGDIVNTNAQYISKELANIGIEVYHHSVIGDNENRLLKELERAFNYCDLVITTGGLGPTKDDLTKESVAKFFQEDLVLHEKSLKQIEKRLLCFNKSMTESNKKQAYFPKNCEILENPNGTAPGFIIEKDNKIAIILPGPPYEMQPMFEKKVMPYLEKLTNCTIKSKVLRITGIGESDVADLISDILESQTNPTVAPYAKQGETTLRITAKANSEEKALNLIVPIEKKIRQILEDNIYGSGETSLEEVIANILVKRNLTIATAESCTGGLLAGKLINFPGISSVFLEGAITYSNESKINRLNVKKETLEKYTAVSKEVALEMAEGIAKSSGTNIGISTTGVAGPGGGTYDKPIGLVYIGLYINGKTFVKELNYSGNRQFIRNITVTRALDFLRRNLK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: CB24_SOLLC
Sequence: MATCAIQQSAFVGQAVGKSQNEFIRKVGNFGEGRITMRRTVKSAPQSIWYGEDRPKYLGPFSEQTPSYLTGEFPGDYGWDTAGLSADPETFARNRELEVIHCRWAMLGALGCVFPEILSKNGVKFGEAVWFKAGSQIFSEGGLDYLGNPNLVHAQSILAIWACQVVLMGFVEGYRVGGGPLGEGLDKIYPGGAFDPLGLADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPIENLSDHINDPVANNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 4, chloroplastic, LHCII type I CAB-4, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: SRA9_CAEEL
Sequence: MATIACASIIEQQRLRSSNFVIAQYIDLLCIVITFVTTYPAIQLVLNKSLFQWSTKMLILESLFFANLYQIFYGIEAITILYKHHFMTSDFCNIMQTESNCAPYLKVILGTTGGMIFAQTGLMIERTCATFLASYRKRKSEIIGFSITIIVFFCSSITGKLFIWDDPLDGMVLGCFILPKNSYKRYNTYFTVCTVLPLFNLGISILLKIYNTKLEYSSRFEVSARFQKREVIDSTGTVCFLAFSLFILLFIYSVGVGALRHLLHENIISQEDFNLCVVWLYTIPFIAMLLPLLLIYRIRRTRSNRIEMLIEFTKQKQSQENHISQMKNMWS
What are the official names of this protein?
Serpentine receptor class alpha-9, Protein sra-9.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAA_ACTSZ
Sequence: MNRNTSSLWADCLLQLQDQVPADKFQMWLRPLQADISSPNQLTIYVQNFFSRQWVENNYLADITKLARQLTGNPDFVVKLVEGVKPAPKQNNIVTTKQNAETAVDSEQHLQSVEFKTGLNSNHLFENFVEGKSNQLARAVGIKVANNPGDKTANPLFLYGGTGLGKTHLLHAVGNGILANNPKARVLYIHAERFVQEYVKATKLGAAENFKKFYRNLDALLIDDIQFFAGKELTQEEFFNTFNNLFEGEKQIILTSDRYPREIEKIEDRLKSRFSWGLSVAIEPPELETRVAILMKKAEERGVNLAEEVAFFIGQKLRTHVRELEGALNRVIANAEFTGKTITIDFVRDTLKDMLALQDKLVTIDNIQKVVAEYYRIKVSDLNSKNRSRSVARPRQLAMALAKELTNRSFPEIGKNFGGKDHTTVIYACDKIQELRETDSSIQEDWSNLIRTLSA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_XANCP
Sequence: MNQQPLPPQSERRALAIGRAVYEAFQDYHAQFSQITARARQRFETRDWSGAREDAVARIALYDHYISECMLRLRAVLLGQAHDRALWMRARTHYAELLTGLIDQELYKTFYNTLTRRYFRTQGVDAQIEFIALDIEPTDAITVPVARHTYAVSPGRLTEMLVRVLGDYPFEVPYAHRTRCAAAIAVRLLDDLAHWGEHPVRSVELLETVFYRERRAYLVGRLFGEHRFSPCVIALVNDDAGLRAEAVLTRRSDVAQLFSNSRSYFQADLTTVGDAVVFLRSLLTHKPIDELYTMLGRAKQGKTERYRTFFRHFQAHPAEQLVHADGTPGMVMVVFTLPSYPLVFKLIRDRFAYPKTMSRAQVEGKYELVFQLDRIGRLLDAQPYRFLRFPKARFSPALLQDLQSSCAMSLSEDGDDVLIALCYVQRRLRPLNLYLREQLPAAAHAAALDYGQAIKDMARNNIFPGDMLLKNFGITRHQRAVFYDYDELCLITECTFRDWPTPTSYEEQMAAEPWFHVGPRDVFPERFALFMGLPSSQLEAVKHMHPELFDPQWWRDLQARLREDDYPDTPPYADAQKLA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_ASPFU
Sequence: MSIDVNWRFATSGPDGEALAERIRSFIHDRFQQVALPRFIRSVQVHAFDFGTIPPELEIKDFCEPFADFYEEDDDDHTSDASEERGEEHSSRWNSTHPELNEPSYREDTAVNHSLRDPFPDGFPTSPLRSPLGEHLNPHFLPRASTPGIPGGTSTLGYHLMSLGGLSGTQTPLAAVAGGNPFASGWSDSGMGPGNRGRSETHAGMQHPRAEPEIDTSNSTSRPSTANTLPSHPSGSSKNSGQAATGRNDHPSLHAGEHLEDSVTQGQLPLPPRMRERRPEDFQVLCHVKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNVTGITFDGVAVIAYIRKRVHFCFLSAEDADALIGPEQQQQRESAGDDHRPQSRPDSSASASQKRHGGLLQEIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFEEELVYPSFWTFLI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RECA_BAUCH
Sequence: MAIDENKQKALAAALSLIEKQFGTGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIATAQKEGKICAFIDAEHALDPIYAKNLGVDIDNLLCSQPDTGEQALEICDVLTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHIGLAARMMSQAMRKLTSNLKNANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSVKEGDVVVGSETRVKVVKNKVAAPFKQADFQITYGKGINIHGELVDLGVKNNLIEKAGSWYSYNGNKIGQGKNNVCNFLKYHPQLAAELDKKLREMLLHNTTRTESNSLVRDDEGTFDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUFY3_RAT
Sequence: MSALTPPTDMPTPTTDKITQAAMETIYLCKFRVSMDGEWLCLRELDDISLTPDPEPTHEDPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLKAKKTFLGQNKSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEANALMMEEEGAIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGSEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELAVANNRIITLQEEMERVKEESSYLLESNRKGPKQDRTAEGQALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSLRQQLDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQSEKDLVKQAKTLNSAANKLIPKHH
What is the function of this protein?
Plays a role in the generation of neuronal polarity formation and axon growth (PubMed:17439943).  Implicated in the formation of a single axon by developing neurons (PubMed:17439943).  May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (PubMed:17439943).  Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (By similarity).  Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity).  Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (By similarity).
What are the official names of this protein?
Protein RUFY3, RUN and FYVE domain-containing protein 3, Rap2-interacting protein x, RIPx, Single axon-regulated protein, Singar.
What are the subcellular locations of this protein?
Cytoplasm. Endomembrane system. Cell projection, invadopodium. Perikaryon. Cell projection. Cell projection, growth cone. Cell projection, filopodium. Cell projection, lamellipodium. Note=Localized in F-actin-enriched filopodia and lamellipodia at axonal growth cones (PubMed:17439943). Colocalizes with PAK1, F-actin, myosins and integrins in invadopodia at the cell periphery (By similarity). Colocalized with Ras-related Rab-5 proteins in cytoplasmic vesicles (By similarity). Accumulates in axon growth cones in a F-actin-dependent manner (By similarity). Colocalized with FSCN1 and F-actin at filipodia and lamellipodia of axonal growth cones (By similarity). Colocalized with DBN1 and F-actin at transitional domain of the axonal growth cone (By similarity).
Protein: ACPH_SALNS
Sequence: MNFLAHLHLAHLADSSLSGNLLADFVRGNPATHYPPDVVEGIYMHRRIDVITDNLPEVREAREWFRHETRRVAPITLDVMWDHFLSRHWTQISPDFPLQAFVGYAHAQVATILPDSPPRFVNLNDYLWSEKWLERYRDMDFIQNVLNGMANRRPRLDALRDSWYDLDAHYDALEERFWHFYPRMMAQAARKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: MICA_HUMAN
Sequence: MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHRDATQLGFQPLMSDLGSTGSTEGA
What is the function of this protein?
Seems to have no role in antigen presentation.  Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells.  Ligand for the KLRK1/NKG2D receptor.  Binding to KLRK1 leads to cell lysis.
What are the official names of this protein?
MHC class I polypeptide-related sequence A, MIC-A.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family. MIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Infection with human adenovirus 5 suppresses cell surface expression due to the adenoviral E3-19K protein which causes retention in the endoplasmic reticulum.
Protein: SCP_SHV21
Sequence: MHRLRVTDPVVQGKLEESDSTHELVKRLEILPQNNMTPEEYTLMKRNYLVFLIAQYNFDQYIETTHGIKRKKHIEGLKANLKPSALSADSASLSGLLSTSLTTPSLSSTPTSLTSMPGLSISGPSTTDTIDSKKKPKAK
What is the function of this protein?
Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument.  Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.
What are the official names of this protein?
Small capsomere-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae small capsomere-interacting protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: UBIX_HELPY
Sequence: MKLVLGISGASGIPLALRFLEKLPKEIEVFVVASKNAHVVALEESNINLKNAMKDLRPSGTFFNEQDIHASIASGSYGIHKMAIIPASMDMVAKIAHGFGGDLISRSASVMLKEKRPLLIAPREMPLSAIMLENLLKLSHSNAIIAPPMMTYYTQSKTLEAMQDFLVGKWFDSLGIENDLYPRWGMN
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: TKT_SINMW
Sequence: MNVSQQIEPRAAASERNMADAIRFLSMDAVEKANSGHPGMPMGMADAVTVLFNRFIRIDPSLPDWPDRDRFVLSAGHGSMLLYSLHHLIGFADMPMAELSSFRQLGSKTAGHPEYGHALGIETTTGPLGQGISTAVGMAMAEQMMASRFGSALCNHFTYVVAGDGCLQEGISHEAIDLAGHLKLRKLVVLWDDNRISIDGSTDLSTSMNQLARFRAASWDAQAVDGHDPEAVAKALERARRTRKPSLIACRTRIGKGAASMEGSHKTHGAALGDKEIAATREKLGWPHPPFFVPPEIRAAWAKVAARGRTAREAWDIRLDASRSKKRYEQTIRRQFDGELGDLLAKFRSAHRTRATKVATRQASQMALEVINGATALTIGGSADLTGSNLTMTSQTQPISPGNFKGRYLHYGIREHGMAAAMNGIALHGGFIPYGGTFLVFSDYARGAMRLSALMGLPVIYVLTHDSIGLGEDGPTHQPVEHLAMLRATPNLNVFRPADIIETAECWEIALGEKNTPSVLALSRQALPMLRRTEGNENQSALGAYVLREARGNRDITILATGSEVEIAVAAAERLQAEEGIAAAVVSMPCWEKFEVQDLAYRRKVLGDAPRIAIEAAGRLGWDRWMGPDGAFVGMTGFGASAPAGDLYRHFGITADHVVAEALELLRRAYSETLPIGARIGPHPSAHTVRSSQEA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: SWP12_NOSB1
Sequence: MKDFKKKIIMKISRIEYKHTAFSAEYKDVEKVYKKLRDNMDKVATGINNLMTYEHGGSAMKKIYHGLSMVSSASRMNYFSDADIFEGFARINKDLTDSDLDEGVREVGRKTAEAYENISKAKEKFNEQCGREMEVLMSMKKRAETTDKERENAKIYRYDLEKAKQSNNPEDQEEVDRLSELFENSQTRTIEMMRDFIGADGLQGVLTRVRDLNIEFHQESVKALERTK
What are the official names of this protein?
Spore wall protein 12.
What is the protein family that this protein belongs to?
Belongs to the SWP12 family.
What are the subcellular locations of this protein?
Spore wall.
Protein: PMP22_MOUSE
Sequence: MLLLLLGILFLHIAVLVLLFVSTIVSQWLVGNGHTTDLWQNCTTSALGAVQHCYSSSVSEWLQSVQATMILSVIFSVLALFLFFCQLFTLTKGGRFYITGFFQILAGLCVMSAAAIYTVRHSEWHVNTDYSYGFAYILAWVAFPLALLSGIIYVILRKREL
What is the function of this protein?
Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
What are the official names of this protein?
Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UPP_PECCP
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLATEKVTIDGWCGPVEVDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGIYRDEETLEPVPYFQKLVSNIEERMALVVDPMLATGGSMIATIDLLKKAGCHSIKVLVLVAAPEGIAALEKAHPDIELYTASIDKGLNEQGYIMPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYE_CORU7
Sequence: MSEVRVRFCPSPTGTPHVGMVRTALFNWAYARHTGGKLIFRIEDTDAQRDTEESYQAIIDSLKWLGLDWDEGIETGGPHEPYRQSQRMDIYAEVLEKLKAAGEVYPAYSTPEEVEERHKAAGRDPKLGYDNYDRDLTEEQIAAFEAEGRKPVWRLKMDHDRRYTWTDLVRGEMDVDGKTMPDFVVARSNGQPLYTLVNPLDDALMGITHVLRGEDLLPSTPRQIALYEALIRIGVAKEVPTFAHLPFVTGEGNRKLSKRDPESNLFNHRDAGVIPEGMLNYLSLLGWSLSADEDIFTMAQLIENFDIADVKPNPARFDHKKMEAINADHIRMLDLADFTQRLRTYLEEFKGWPADYPADKFAFAAELVQTRIKVLGDADGLLRFLLTKDEDLELEPKAARKNLKEAAKEPLEAAIEELEAIAEEDFRTEPIEQALSTRLIEQMELKPRVAYGALRVAICGQAVSPPLFESMELLGKDSTLVRLRAGLEQTPFQAEQPAN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHHT_ECO57
Sequence: METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFAIVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELTRKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVFMLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELMGVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIGNILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKLAILLGPGRPKSRLPG
What are the official names of this protein?
Putative transport protein YhhT.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCS2_HALMA
Sequence: MDATGSAEHFTRMGTLGIEEEFYVVDEFGRPTSGTDELVYETEPPAVLDGRLDHELFKCVIETQTPRIDDPANAGDHLRSVRDALVDHAEANGFGIAAAGLHPLAKWRELEHAEKPRYKSQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWVANELRWHLPLMLALSANSPYWNGFDTGLQSARGKIFEALPNTGMPTTFDDYDAFETYEQRMLETGSIDDRGELWFDVRPHSGHGTVEVRAPDGQADPDRVLAFVEYVHELVVDLAERYEDGESGRRLRREFLDENKWRAIRHGQSAELLSRDLSTTRSVEELVEIESDRLGVDGLWELYHRESGAERQRRLRSEEGVMALADSLRLS
What is the function of this protein?
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-glutamylcysteine synthetase, GCS, Gamma-GCS.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: CKC_CONCB
Sequence: GYEEREIAETVRELEEA
What is the function of this protein?
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.
What are the official names of this protein?
Conantokin-Ca2, Con-Ca2.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_AZOSB
Sequence: MLDIQLLRGQLSQVAERLALRGVTLDSGAFTALEDERKQLQTRTQELQAKRNALSKQIGILKGKGEDASAVMAEVGQLGDELKACEQALPVVLEKLNAFLAGLPNLPQEGVPVGEDETGNVEVRRWGTPRSFDFEVKDHVDLGAALGLDFDTGAKLSGSRFTFMRGQIARLHRALAQFMLDTQTLEHGYTECYAPYIVNREVLVGTGQLPKFKEDMFWVLRGGDEEGGEQYLISTSEIPLTNTVREQILAADALPIKLTAHSPCFRSEAGSAGRDTRGMIRQHQFDKVEMVQIVHPDASNAALEEMVGHAEAILQKLELPYRVITLCTGDMGFSAAKTYDLEVWLPAQNTYREISSCSNCEAFQARRMQARFKTAQGKNELVHTLNGSGLAVGRTLVAVLENYQQADGSIVVPKALVPYMGGLEVLRPAS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT331_ASPTN
Sequence: MKAWLLVSSLCLSTFIAALEQTIISTAAESISRSLHTTELEFTWIGTAYLLPAAASTPPWGKLSDIFGRKPVLMISIVVFFIGSLIGALAINIDMLIAGRVIQGTGGGGILGLSATVIGDVFSPRERSKYYGVLGVTWGVACGLGPIVGGAFCQYVSWRWCFWINRTSLPQSSPNPLNLTTSVPVAGVAGALVLLFLEVHTPRTPIIEGLLAMDWLGTITIVGATVMFLLGLGYGGIAYPWNSATVVCLIVFGIGDNRRLRPDRMEGRQVLDHAAAPVQIPPPISPPSASAYIHGLRLHRPTLYYPPAVLSRSCSAPPRSLSGVYLLPVAVTLCVASTATGLYISHSGRYRPPIYFGLVMMILGHGLYINLQPYASWARIIIFQIIAGLGLGPLFQAPIIAIFSLTKPADTASAAATVFFARDIATAMSIVFGGVIFQNRIRAFKSDIEGVVSPELTELITSGGATTASDQIRALPAAARSLVRDRYNTALRSEWIFYTALSGAALLLSVFISKQVLSRDHKMNKTGLDVQEASRLEELEKEKKAAATDAV
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of isoflavipucine (PubMed:21236704).
What are the official names of this protein?
MFS-type transporter ATEG_00331, Isoflavipucine biosynthesis cluster protein ATEG_00331.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL2_PARL1
Sequence: MALKKYKPTSPAQRGLVLVDRSALYKGKPVKDLTEGLTKSGGRNNHGRITVRFRGGGHKRSYRTVDFKRRRYDVPATVERLEYDPNRTAFIALVKYEDGELAYILAPQRLQPGDVVISGSRVDVKPGNAMPLANIPVGTIVHNVEMKPGKGGQIARSAGTYVQLVGRDQGYALLRLSSGEQRMVPATCMASIGAVSNPDHSNITIAKAGRNRWLGKRPHVRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRANKATDKYIVRSRHQKKKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.