PharMolix/UniProtQA huggingface dataset:
Protein: AP2S1_RAT
Sequence: MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
What is the function of this protein?
Component of the adaptor protein complex 2 (AP-2).  Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways.  Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation.  AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.  The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components.  Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation.  AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis.  AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface.  AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules.  AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway.  The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.  May also play a role in extracellular calcium homeostasis (By similarity).
What are the official names of this protein?
AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, Plasma membrane adaptor AP-2 17 kDa protein, Sigma-adaptin 3b, Sigma2-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
Protein: KEFF_SALCH
Sequence: MILIIYAHPYPHHSHANKRMLEQAGTLENVEIRSLYHLYPDFNIDVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLWAVTTGGGENHFTIGSHPGFDVLSQPLQATALYCGLKWLPPFAMHCTFICDDDTLQAQARQYKQRLLAWQEVNHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS1_ZYMMO
Sequence: MTKPLVFAIPKGRILKEALPMLEAAGIIPEPAFLDKESRLLRFKTNRPDIEIIRVRAFDVATFVAHGAAQMGIVGSDVIEEFSYPELYAPVDLDIGHCRLSIAEPKRLAKDDDPREWSHVRVATKYPHLTHRHFEARGVQAECIKLNGAMEIAPALGLAGRIVDLVSSGRTLEENGLVEVEKIMPISARLIVNRAAFKMRAGDIAPLVENFRRLVGVADNVA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1477_BRUSU
Sequence: MTDKPFWQTKNLNQLTRSEWESLCDGCGQCCLHKLQDEDTDEIYWTSVACTLLNPETCQCRDYPNRKKTVPDCVFLTPEIVDEVDWLPVTCAYRLVAEGSDLYWWHPLVSGSPETVHEAGISVRGKVTAFDHDMQDDDDYLDHMVTPDKIAR
What are the official names of this protein?
UPF0260 protein BR1477/BS1330_I1471.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SCPB_BACP2
Sequence: MTLDIVNWKAIIEALLYAAGDEGLTKKQLMSVLEVEEVALLDMMSAVKEEYQKQERGIELIEYADSYMLLTKKEYSIYLKKLVETPSKGLSQAALEVLAIVSYKQPITRSEVEEIRGVKSERVLHSLVAKALLCEVGRADGPGRAILYGTTPTFLEQFGLKALDELPPLPENVEADGVQEEADLFFENFNQTFEEIK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: SULA_KLEP7
Sequence: MFTSAHANRSAQASAPAGHYAHRSGEQNTNGLISEIVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQSAGLPLSKVMQISQLSPSHTIDSMIRALRTGNYSVVICWLAEELTADEHERLVNAAQVGSAMGFIMRPVRNQGTLGRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: COXZ_EHRRU
Sequence: MTQKAKNTIYLLILIILSMLCLVYASVPLYSIFCKVTGYGGTVRTTTVTQSKLGKTTIKIRFNADINKELPWKFYPEIPYTTVKPGEQKLIFYRAENLTNEYVSGMAVYNVTPYKVGKYFNKVACFCFTKQTLSPYQKTIMPVSFFIDQVYIN
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: CAL_ARALL
Sequence: MGRGRVQLKRIENKINRQVTFSKRRAGLLKKAQEISVLCDAEVSLIVFSHKGKLFEYTSESCMEKVLERYERYSYAERQLIAPDSHINAQPNWSMEYSRLKAKIELLERNQRHYLGEDLEPMSLKDLQNLEQQLETALKHIRSRKNQLMYESLNHLQRKENEIQEENSMLTKQIKERENILRTQQTQCEQLNRNHDVPPPQPQPFQHPHPYMISHQTSPFLNLGGMYQGEDQTAMRRNNLDLTLEPIYNYLGCYAA
What is the function of this protein?
Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1, FRUITFULL and LEAFY.  Is required subsequently for the transition of an inflorescence meristem into a floral meristem.  Seems to be partially redundant to the function of APETALA1 (By similarity).
What are the official names of this protein?
Transcription factor CAULIFLOWER, AlCAL, Agamous-like MADS-box protein CAL.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGA_RHILW
Sequence: MKVLSVSSEVFPLIKTGGLADVSGALPIALKAFGVETKTLLPGYPAVMKVIRDPVVRLEFPDLLGEPAAVLEVQHEGLDLLILDAPAYYDRPGGPYVDPLGKDYPDNWRRFAALSLAASEIAAGLLPGWRPDLVHTHDWQAALTSVYMRYYPTPELPSVLTIHNIAFQGQFGPEIFPGLRLPAHAFATDSIEYYGTVGYLKGGLQTAHAITTVSPTYADEILTPEFGMGLEGVIASHIDNLHGIVNGIDTDIWNPATDPVVHTHYGPTTLKNREENRRSIAEFFHLDNDDAPIFCVISRLTWQKGMDIVANIADEIVAMGGKLVVLGSGEAALEGALLASASRHPGRIGVSIGYNEPMSHLMQAGCDAIIIPSRFEPCGLTQLYGLRYGCVPIVARTGGLNDTVIDANHAALAAKVATGIQFSPVTETGMLQAIRRAMHFYADRKLWTQLQKQGMKSDVSWEKSAERYAALYSSLVSKGM
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RS13_ACIBS
Sequence: MARIAGVNIPDNKHAVISLTYIFGIGRHTAKNILAAVGITETTKIRELDDAQLDAIRAEVAKVPTEGDLRREISMNIKRLMDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: AMPA_ACIF5
Sequence: MEIAVQCQNPTTDNSDCVVVGIYEGGILSPAATLVDLASGGALRALLDTGDFTGDCGDTQLLYQVPGMAAARVLVLGLGSHGKVKDSQFRKAALAAARALQGARVGRASLHLLDTPVIRRSAPACAKILVQAVADAEYHFDRHKKPADAPQRPISELQLSISENDTAALAELQGAVAEAQATARAVAWTRDMANEPGNICTPTWLAEQAEAMAGRLGIKSTILGPDAMEALGMHLLLGVAHGSRQPPRLIILEYRGGAENQAPIVLVGKGITFDAGGISLKPADKMDEMKYDMCGGASALAAIQAAAELQLPLNIVTVVPASENLPDGQATKPGDIHRSMNGLSVEVVNTDAEGRLILADTLTYVERFEPDVVIDMATLTGACIIALGHQTAAVMGNHEGLVHDLIAAGKESMDRVWELPLFEEYQEQLKSPVADLSNVGGRPAGTITAACFLSRFTENYRWAHLDIAGVAWKSGEHKGATGRPVPLLVEYLLRRARQVA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEN3D_PENVA
Sequence: MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGCPISCRGISFSQARSCCSRLGRCCHVGKGYSG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-3d, Pen-3d.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: FABZ_ANAPZ
Sequence: MQMDHKQVMRALPHSYPFLLVDKVTECIPGECIVAVKNVTFNEPFFVGHFPGNPIMPGVLIVEALAQASMLCVVCDADGESTGDTSVLFMSIDSARFRKVVVPGDVLVLKSSVCHRRGNSCRFDCRAYVEDVLVTEAQILAMMNK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_NOSS1
Sequence: MISGVSALPFVRVRQHVNPLAQKYLTPANPLEWEKAYSTPHQPLHLDIGCARGRFVLQMAQVEPNWNFLGLEIRESLVIEANQFRSQLGLTNLHYLYCNANNSLQPLLSSLPTGILQRVTIQFPDPWFKTRHAKRRVVQPELVQDIANYLAVGGVVFLQSDMEFVAVEMCDRFAANPAFKKVGTGEWLTENPLPVATERETTTQNRGEPVYRALFERSS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: 2A5Z_ARATH
Sequence: MIKQIFGKLPRKPSKSLQNDSNGEGGVNNSYYASNSSTTSISKPSSTSSKSSSASGSRVANGTLAPNSMSSNRNTNQGKKPLGGDAVVQAGPFPSSGGVYEALPSFRDVPISEKPNLFIGKLSMCCVVFDFSDPSKNLKEKEIKRQTLLELVDYVASVGFKFNDVSMQELTKMVAVNLFRTFPSANHESKILEIHDMDDEEPSLEPAWPHVQVVYEILLRFVASPMTDAKLAKRYIDHSFVLKLLDLFDSEDQREREYLKTILHRVYGKFMVHRPYIRKAINNIFYRFISETEKHNGIAELLEILGSIINGFALPLKEEHKLFLLRALIPLHKPKCSSVYHQQLSYCIVQFVEKDFKLADTVIRGLLKYWPVTNSSKEVMFLGELEEVLEATQAAEFQRCMVPLSRQIARCLNSSHFQVAERALFLWNNDHIRNLITQNHKVIMPIVFPALERNTRGHWNQAVQSLTINVRKVLCEIDQVLFDECLAKFQVEEVNKTEVKAKRERTWQRLEDLATSKTVVTNEAVLVPRFVSSVNLTTSSSESTGS
What is the function of this protein?
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).  The holoenzyme composed of PP2AA1, PP2A4 and B'ZETA acts as negative regulator of plant innate immunity by controlling BAK1 phosphorylation state and activation in surface-localized immune receptor complexes (PubMed:25085430).  Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signaling by dephosphorylating and inactivating BRI1 in the cytoplasm (PubMed:26517938).  Involved in growth regulation and stress signaling.  Involved in the regulation of reactive oxygen species (ROS) signaling (PubMed:26012558).
What are the official names of this protein?
Serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' zeta isoform, AtB' zeta, PP2A, B' subunit, zeta isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion.
Protein: RK2_PICAB
Sequence: MAIRSYRILTPDTRNRSVSGFDGRVQLDPQKKLTSGQHHCGSRNGRGIITARHRGGGHKRLYRQIDFRRDKEHISGKIVTIEYDPNRSAYICKVHYKNGDKMYILHPRGVMIGDTILSGPKAPISIGNALPLTNMPLGTAIHNIEITLGKGGQLARAAGAVAELIAKEDRSATLRLPSGEVRLISENCSATIGQVGNITANNRSFGKAGAKRWLGKRSEVRGVAMNPVDHPHGGGEGRTPIGRKKPVTPWGYSALGKKSRKRNRYSDASILRRRE
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HBB_ANSSE
Sequence: VHWSAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTERFFSSFGNLSSPTAIIGNPMVRAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPDCQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PRP6_HUMAN
Sequence: MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF
What is the function of this protein?
Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:28781166, PubMed:21549338).  Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
What are the official names of this protein?
Pre-mRNA-processing factor 6, Androgen receptor N-terminal domain-transactivating protein 1, ANT-1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles.
Protein: HTF_PRIVA
Sequence: QVNFSPGWGT
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, PriVa-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: F16P2_RABIT
Sequence: MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGIAGTVNVTGDEVKKLDVLSNALVINMLQSSYSTCVLVSEENKEAIITAKERRGKYVVCFDPLDGSSNIDCLASIGTIFAIYRKTTEDEPSDKDALQPGRNIVAAGYALYGSATLVALSTGQGVDLFMLDPALGEFVLVEKDVKIKKKGKIFSLNEGYAKYFDAATTEYVQKKKFPEDGSAPYGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGTQPVLDVKPESIHQRVPLILGSPDDVQEYLACVQKNQAGR
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase isozyme 2, FBPase 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase 2, Muscle FBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
Protein: IQCF5_MOUSE
Sequence: MGPEKSTAMTETSAAVRIQAWWRGTLLRRTLLHAALSAWIIQCWWRKIMIMLQGKKRRMALELYARKTWAIVKLQSWFRMWHIRHRYCRLLNAVRIIQVYWRWHSCHTRGFIQGNYEIKENRLNIQLEISLGSQACKVEQCITLPIKE
What are the official names of this protein?
IQ domain-containing protein F5.
Protein: HEMH_PASMU
Sequence: MNKAKTGVLLVNLGTPESPTPKAISRYLWQFLTDPRVVDLPRYKWFPLLKGIILPLRAKRVAKNYASIWTEQGSPLLTITREQQHALQTYFKQQEKNIVVEVAMTYGEPSIKSAMQRLSTQQVDNLIVFPLYPQYSSSTTGAVFDAFAQVLKTQRGVLPFDFIHSYHTNEDYIAALVTTIQEHFQPDEFLLFSFHGIPVRYENMGDYYREHCKQTVLAVIDRLGLTENQWGLSFQSRFGKEEWLQPYTDQFLAQAPSQNIQKMAVICPGFAADCLETLEEIEEENKEIFLANGGISYRYIPALNARPEHIQMMANLILNKLNQTSK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_SHEFN
Sequence: MLDPKFLRNELEITAERLATRGFILDVDNLTKLEEKRKSLQVATEDLQASRNAISKSIGQAKARGEDTSSIMAQVGDLGAQLDSKKAELAELLQQINSIAMSVPNLPDESAPVGADENDNVEVRRWGTPKVFDFEVKDHIDLGEALEGLDFKNAVKISGSRFIIMRGQIARLNRALGQFMLDLHTTEHGYTETYVPLLVNEESLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNYVRDMIVDETELPMKMTALTPCFRSEAGSYGRDTRGVIRLHQFDKVELVQIAHPDHSMQALEDITSHAEKVLQLLNLPYRTMVLCTGDMGFGSSKTFDIEVWLPAQNTYREISSCSNMKDFQARRMQARYRSKADNKPALLHTLNGSGLAVGRTLVAVIENYQNQDGTITVPEALRPYMGGLSLIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_HALVA
Sequence: MMSEPVRVGLNGFGRIGRNVFRASLHSDDVEIVGINDVMDDSEIDYFAQYDSVMGELEGASVDDGVLTVDGTDFEAGIFHETDPTQLPWDDLDVDVAFEATGIFRTKEDASQHLDAGADKVLISAPPKGDEPVKQLVYGVNHDEYDGEDVVSNASCTTNSITPVAKVLDEEFGINAGQLTTVHAYTGSQNLMDGPNGKPRRRRAAAENIIPTSTGAAQAATEVLPELEGKLDGMAIRVPVPNGSITEFVVDLDDDVTESDVNAAFEDAAAGELEGVLGVTSDDVVSSDILGDPYSTQVDLQSTNVVSGMTKILTWYDNEYGFSNRMLDVAEYITE
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA2_BRASB
Sequence: MIDREAPAAVLAPTPLLRHAIERACRRIAPVWPLKNFVAVNPFLGFSDRSFHATCAMLHRVARIDTLMPRAFYREAIRNGTIETADLAAALAAAPADWRLPTEAAELLKLADNDRIARKPPAVVATVAEVLNELAAGDRHVARTAFMTDEISRWCAAYFDEGQSVWRMPARGLRPYAAWRAWVRYDRNPEMMGIARFRALVADMPDDYVAAIATVIERLGIPARAVEDYLHQALLEIGGWAAYARYLMWNHELAGDRDDTLEQLLAIRVVWGYTLFAQRTDTAFREAWRRAMEQAALPPLDDQLGGDPDFCINMVLQEAYEIAFRRRLLDRLAGAPAARTAGARPAVQAAFCIDVRSEVYRRAMESVGDGVETVGFAGFFGFPIEFVPIGHVTGRAHCPVLLRPQFTVCEAVGGTSEEEDSEILVMRLLRRRVRKAWKSFKLSAVSSFIYVETAGLLFAGKILSDSLAVTRTVHDPNTDGLDDDLIGRLGPRIEPRPVGGRATGFDPAQRVAMAEAVLRAMSMTGPFARLVMLTGHGSTTVNNPHASGLDCGACGGHTGEANARVAAAILNDPDVRVALRQRGIDIPDDTVFLGCLHDTTTDVIRLFDIEQLPASHADDLRRLRALLAKATSLTRLERAALLGIARGAATEQQVVTRSRDWAQVRPEWGLAGNASFIAAPRARTRGIDLGGRSFLHDYDWQQDKDFGTLQLIMTAPMVVASWINLQYYGSTVNNAAFGAGNKVLHNVVGTLGVLEGNAGDLKVGLPWQSVHDGSRFVHEPLRLTVLIEAPLEAINGVIAKNDIVRELVDHHWLHLYAISPQGRVSHAYRGHLLWQQLEERSES
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 2.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOZ_TRIEI
Sequence: MQKQSNINSVELSRKSEELIKASSNRYRAVVQVANRAKRRRYEDFDNFDEQAVKPVIRAVLEMSDELMQPEIISEVGNNIDR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.