PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_SHEFN
Sequence: MTAQIIDGKAIAQSIRTTLKQKVTQRRQAGFRAPGLAVILVGSDAASQVYVGSKRKACEEVGFESQSFDLDTETTEAELLALIDECNANPSIDGILVQLPLPAHIDDSKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGIDTYGLDATVVGASNIVGRPMTLELLLAGCTTTTCHRFTKNLEQKVRQADLLVVAVGKPGFIPGDWIKPGAIVIDVGINRLENGSLVGDVEFNVAAEKAAFITPVPGGVGPMTIASLLENTLYACEQYHS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DER_BURL3
Sequence: MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEEADEDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDEHARDRAKADLTRKLKFLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIHGNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL362_SALCH
Sequence: MQVLNSLRNAKQRHPDCQIVKRKGRLYVICKTNPRFKAVQGRKKRR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CYSM_PSESY
Sequence: MTLQYQTIADCVGNTPLVRLQRMAGNTSNTLLLKLEGNNPAGSVKDRPALSMITRAELRGQIHPGDTLIEATSGNTGIALAMAAAIKGYRMILIMPDNSSAERKAAMTAYGAELISVSKDDGMEGARDLAERMQAEGRGKVLDQFANGDNPEAHYTSTGPEIWRQTGGT
What are the official names of this protein?
Cysteine synthase B, CSase B, O-acetylserine (thiol)-lyase B, OAS-TL B, O-acetylserine sulfhydrylase B.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: YBEY_SHEAM
Sequence: MALELALDLQFAVNPGNLPTEAEFETWVRVALGDTLDEAELTIRIVDATESQQLNRDYRGKDKPTNVLSFPFEAPPGMELPLLGDLVICASVVENEALEQHKALEAHWAHMVVHGCLHLLGYDHIDDAEAEEMEALETTLLTGLGYPDPYKEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAAT1_DROPS
Sequence: MELKGVHQQNGTSNGTGAAGTEGESPPPAPAPATAEAAASLETTTEKVDAEQQKTERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFATICIITYYSSLLALTLFYLFVSFQSVLPWSYCWEEWMNCVDSRPQEDTDALLLSSSNVTNVTALTDTVKLQSSSELYFLNVVIKEKMDISDGIGDPDWKLTLALFVSWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFILLVRAVTLEGARDGIIFFLEPQWGELLNPTVWKNAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTILCDQFKSWKYWKVALATSICGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWIYGMQNFCDDVEFMCNRRVSLYWRVCWSFFTPVMMIVIFIYSMVTIEPITYSEQFFPEAGNVAGWLLFGIGAAQFPLWWMWYISHHREGSLGQSFVASLRPSDKWGPANPETKRQWVIFKNEKAAQRATKKQSSKMGAFWQKLGHFCGSNT
What is the function of this protein?
Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids.  Neutral amino acids are the preferred substrates, especially methionine and phenylalanine (By similarity).
What are the official names of this protein?
Sodium-dependent nutrient amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PIGR_MOUSE
Sequence: MRLYLFTLLVTVFSGVSTKSPIFGPQEVSSIEGDSVSITCYYPDTSVNRHTRKYWCRQGASGMCTTLISSNGYLSKEYSGRANLINFPENNTFVINIEQLTQDDTGSYKCGLGTSNRGLSFDVSLEVSQVPELPSDTHVYTKDIGRNVTIECPFKRENAPSKKSLCKKTNQSCELVIDSTEKVNPSYIGRAKLFMKGTDLTVFYVNISHLTHNDAGLYICQAGEGPSADKKNVDLQVLAPEPELLYKDLRSSVTFECDLGREVANEAKYLCRMNKETCDVIINTLGKRDPDFEGRILITPKDDNGRFSVLITGLRKEDAGHYQCGAHSSGLPQEGWPIQTWQLFVNEESTIPNRRSVVKGVTGGSVAIACPYNPKESSSLKYWCRWEGDGNGHCPVLVGTQAQVQEEYEGRLALFDQPGNGTYTVILNQLTTEDAGFYWCLTNGDSRWRTTIELQVAEATREPNLEVTPQNATAVLGETFTVSCHYPCKFYSQEKYWCKWSNKGCHILPSHDEGARQSSVSCDQSSQLVSMTLNPVSKEDEGWYWCGVKQGQTYGETTAIYIAVEERTRGSSHVNPTDANARAKVALEEEVVDSSISEKENKAIPNPGPFANEREIQNVGDQAQENRASGDAGSADGQSRSSSSKVLFSTLVPLGLVLAVGAIAVWVARVRHRKNVDRMSISSYRTDISMADFKNSRDLGGNDNMGASPDTQQTVIEGKDEIVTTTECTAEPEESKKAKRSSKEEADMAYSAFLLQSSTIAAQVHDGPQEA
What is the function of this protein?
Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens.  On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
What are the official names of this protein?
Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor.
What are the subcellular locations of this protein?
[Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Secretory component]: Secreted.
Protein: HBA_RAT
Sequence: MVLSADDKTNIKNCWGKIGGHGGEYGEEALQRMFAAFPTTKTYFSHIDVSPGSAQVKAHGKKVADALAKAADHVEDLPGALSTLSDLHAHKLRVDPVNFKFLSHCLLVTLACHHPGDFTPAMHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed:18077343).  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed:18077343).
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: S35B4_DROME
Sequence: MALNLKALLGMLFVFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVRPKIALKDYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDTSYSDFFWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVINQVRDAYRARSSRKTHFDTAPLAKKVE
What is the function of this protein?
Sugar transporter that specifically mediates the transport of UDP-N-acetylglucosamine (UDP-GlcNAc), GDP-fucose and UDP-xylose.  Functions redundantly with nac in the O-fucosylation of Notch, positively regulating Notch signaling.  Involved in the biosynthesis of heparan sulfate-glycosaminoglycan (HS-GAG) and in Dpp signaling in the wing imaginal disk.
What are the official names of this protein?
UDP-xylose and UDP-N-acetylglucosamine transporter, ER GDP-fucose transporter, Solute carrier family 35 member B4 homolog.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DJC27_DANRE
Sequence: MDTNVQKRRENKKSLRVKVISLGNAEVGKSCIIKRYCEKRFVPKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFYEVRNEFYKDSQGVILVYDVGLRESFDALDSWLTEMKQEMGSQANMENIIFVVCANKVDLTKRRVVDESEGRLWAESRGFHYFETSAQSGEGINEMFQSFFSSITDMCENGGKRPTPEVSVGFTKEQADTIRRIRNSKDSWDMLGVKPGATREEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTSLLKNIK
What is the function of this protein?
GTPase possibly involved in regulation of the MEK/ERK pathway.
What are the official names of this protein?
DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Nucleus.
Protein: POTEF_HUMAN
Sequence: MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPCCRGSGKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQKESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEATLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTEHGYRFTTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIHETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLSTFQQMWISKQEYDESGPSIVHRKCL
What are the official names of this protein?
POTE ankyrin domain family member F, ANKRD26-like family C member 1B, Chimeric POTE-actin protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Colocalizes with actin filaments.
Protein: REM1_SCHPO
Sequence: MNSNNKRVALQEISNYVSKSLNVKGWVNAQVREISLQNGCSPSDKHFPSQSWHGISSIEESQIQKDYDSFLASPLEEEIVFTEKQLLVDLDVCSISNVQSPNCSVSEFGIAIEESNDNCAEEDEEEELQMRYSADESVSVEYAKEILSHMEKLEIRFMPDYRHMSAQPYYVTEMRASVINWIVGVHTCINLLPESLFLSINVLDRFLSLQNVPASKMKLCGATALFIACKYEEIHPPTVKDLEIVLEGEWIGEDICGMEKYMLMVLQYQLGWPGPVSFLRLLTIVNKWESQLRIMIKYFLEVSLVEQRFSSLRASQLVATCAYTGQSILQEENWSNTLPQITGYDYMSLVSYVHLLLKCLENPFDHHYAIYSKYATPYFHGISRQVHDWIATNTNLMAMDGS
What is the function of this protein?
Required for pre-meiotic DNA synthesis and S phase progression.  Regulates levels of meiotic intragenic recombination.
What are the official names of this protein?
Meiosis-specific cyclin rem1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RL31_METB6
Sequence: MAEEMKEHIYIIPLRDARRMPRWKRANGAIKDIRKYLAKHMKTEDVKLDKTINEKVWSRGAEKPPSKIRVRAMKMEDGQVQAELALES
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: NCZS_STRCZ
Sequence: MVPISIIRNRVAKVAVGSAAVLGLAVGFQTPAVAAAPTATVTPSSGLSDGTVVKVAGAGLQAGTAYDVGQCAWVDTGVLACNPADFSSVTADANGSASTSLTVRRSFEGFLFDGTRWGTVDCTTAACQVGLSDAAGNGPEGVAISFN
What is the function of this protein?
NCS has antibiotic activity (for Gram-positive bacteria) and antitumor activity (for certain mouse tumors).  NCS binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic.  The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
What are the official names of this protein?
Neocarzinostatin, NCS, Mitomalcin, MMC.
What is the protein family that this protein belongs to?
Belongs to the neocarzinostatin family.
Protein: SPIKE_ADECR
Sequence: MKRTRSALPANFDPVYPYDAPKPSTQPPFFNDRKGLTESSPGTLAVNISPPLTFSNLGAIKLSTGAGLILKEGKLEANIGPGLTTNQEGQITVEKDSDGLTFTSPLHKIENTVSLSIGEGLEDESGTLKVNFPSPPPPLLFSPPLAEAGGTVSLPLQESMQVTEGKLGVKPTTYSPPLQKTDQQVSLRVGPGLTVLNGQLQAVQPPATTYKEPLLETENSVSLKVGAGLAVQDGALVATPPNVTFSAPLEKNGNAVSVRVGAGLSIQGNALVATTSPTLTFAYPLIKNNNHITLSAGSGLRVSGGSLTVATGPGLSHINGTIAAVIGAGLKFENNAILAKLGNGLTIRDGAIEAVAPQPSFTPVTLWTGPDPNVNTSINGTPVIRSFISLTRDSNLVTVNASFTGEGSYQSVSPTQSQFSLILEFNQFGQLMSTGNLNSTTTWGEKPWGNNTVQVQPSHTWKLCMPNREVYSTPAATLTSCGLNSIAHDGAPNRSIDCMLIINKLAGAATYTLTFRFLNFNKLSSSTVFKTDVLTFTYVGENQ
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: IRC5_YEAST
Sequence: MSRCSNAALMTVVEDAVGARVAARTRNMSNGVNYREKEVNDLTADISDSDSDLDSEDNKHGKGDNDTAPIWLQDDVHSDEDIQLDSEDDSDTEAVQAQVVDKLAKDTKSEQKSLDDELSEMDTKTVSLKLKKLNEFVRQSQVYSSIIADTLLHRSNEVANANTKDNSNSDDEEHSSKKRKTKKKSITDFFKKQKKNEDTTTQNGAPDDAAIKQPRLLKNCILKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQMGKFNNLKKLALNEGSFLKANKAGVNVTNKDLVQELSMLLMSDESNIGFENGGQKENKATEGQLTDKEVEELTNRSLEAYKANRVVDLPHVKLFETTSGL
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Uncharacterized ATP-dependent helicase IRC5, Increased recombination centers protein 5.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCD4_MOUSE
Sequence: MTAHLPQEISSRCSTTNIMEPHSRRQQDGEEKMPLQAEDIRPEIKDDLYDPSYQDEEGPPPKLEYVWRNIIFMALLHVGALYGITLVPSCKVYTWLLGVFYNVVAGLGITAGAHRLWSHRTYKARLPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFLRYAVLLNFTWLVNSAAHLYGYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEYRWHINFTTFFIDCMAALGLAYDRKKVSKAVVLARIKRTGDGSHKSS
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:12815040, PubMed:16443825).  Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
What are the official names of this protein?
Stearoyl-CoA desaturase 4, Acyl-CoA desaturase 4, Delta(9)-desaturase 4, Delta-9 desaturase 4, Fatty acid desaturase 4.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Protein: GCSH_SACD2
Sequence: MSELRSELKYLESHEWARVEEDGTVTIGITDHAQEALGDVVFVEVPEVGSQVSIGEEAGVVESVKAASDIYSPVSGEVIAVNEALEDAPETVNSSPYDDGWFFKVKPDDLDELEKALSMEDYKAAIESDD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CFA74_MOUSE
Sequence: MEEPTVQFSDEDLVDNFPPMDDERVQLEDLEFEVERPSEGLEDEGSHSSAKKESKGAEKMRKSTTKDQVQAFHLRKSLNLLDKMHEEKDVFIQKTKGELHICRQRMDLLNKQQESLAAEIATEKEANNMAAIGRLQAASRRLQTELENEKDLQSKITAMLKDSENAMWHIEIQKGQFEDVRKHHEAEAEARQRGLEVHSARQLQREREAMEKSEKNRLLRARKSLHTQKELGLRHQKLVEDAQRNHRIAVKFLKASLGRVREREQKEEMESRTHMQRRMDAVLSLKNNITASRETLKKFQAWGQTRADLAKQKALTEKEVILSQGGDAFKYLFHQRRHQELEAQKRAFEEEQKLRKQEIVNRILKEEAEEEQRKRRQHPLSKPINRRTLRDKTWQYISDFCEGKSVLTSQQERERELLLYPKTVCVIKAISSESVQVDLGSISTEDEVLAEPDISGLWNKESYQVPKEDMERKPVGGSKMEKDILARTMEQLRSGVVQKQVVSGREFKGRPFNSKPEVIHFKDFDIGKVYKKKITLINATYTINYCKLVGVEENLKDFIHIDFEPPGPMSAGMSCEVLVTFKPMINKDLEGNVSFLAQTGSFSVPLKCSTKKCSLSLDKELIDFGTYVVGETTSRIITLTNVGGLGTKFKFLPDSEFYEMDESQPAMKISSLFTCEEKIIYEKIMTSLSEQQLEVNDSSLVDLQSLKESEKQLDDPEVTTAAVSAMTMIPSEEQAEITLGEVTEGEIGPFSSVKVPITFTPVIPGEVQTKFKVMFKNPQSPPLYFRATGTAIDVPVWVPKATVDLKICMYDRLYQDSITVHTRSKAALRLKFEVCKELRGHIELLPETGYIQAQSTYSVQLKFLPRQSLPEDARKYFDPASRVLEAPMTIRVADQIKPVRFTVQAIVTTSDLEINPSEINFGYCTIYEAIRTEICLSNLSLLPQEFGFVGLPKYVDIQPNDGFGTILPLETLHLDVIFQPIKAKEYKFELVCKSEINRCFKVSCQAVGVHPPLELSHYQIKFSATSLYDTSVSTLYVINSHLSMNKMIHSLPRIGSEEAAPVGPTSFEFLLPPNSPITISPSVGTVLPGKRCLIQVAFQPVLPKEIIYKEASQILNKEIETKPVSQKEIVQRKELWKQSFSVVRVHNRDRPTRVSTPQATELQRPVINSSSTEFQIAQATLSKAFQGKFNRFVIPCVVASGDIKDRKTAEPLSFSPHNTLYLELWCPAVAPFIVVTSHKGKTDFNFGDIAVGHRSVKKITLQNICNEDLTLEYSVLNPNGPFVRLNPFNKLRSGETQTLVLSFSPHENILAQETLDIITKRGTLSLTLFGMGVASMITCSIDGNILNMGYVLARESVSTNFKLQNESSLPIKFWVRLESLSRKKAEAHQQLPKFITSHEQRAEIVGTQNYNGQSVFSIVPVEGLMFPGKAQEFTVTFSPDHESLFFSDLLKVVLFEKKVSHQILLKGAAREHMMFVEGGDPLDVPVESLAVVTAFDTEHKEEAEELKPILVTLNYVQLDTDTTTSPATRELQVGCIRTTQPSPRRPDHPLMVSTLLQLRGDVKETYKVTFVAHVVTGL
What is the function of this protein?
As part of the central apparatus of the cilium axoneme may play a role in cilium movement.
What are the official names of this protein?
Cilia- and flagella-associated protein 74.
What is the protein family that this protein belongs to?
Belongs to the CFAP74 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RLMN_HAHCH
Sequence: MSGSSAKINLLGMNRSDLETFFESLGEKKFRATQLMKWMYHLGVSDFDLMTNMSKALREKLKEVAEVSVPEVIYEDISADGTRKWVMRLAGGNSIETVYIPDNGRGTLCVSSQIGCSLDCSFCSTGKQGFNRNLSSAEIIGQLWIAARSFGDYDLSKERYVTNIVFMGMGEPLLNFDNVVRACDVMMDDFGFGISKRRLTVSTSGLVPALDKLGDVTDVSLAISLHAPNNSLRDVLVPVNKKYPIEELLAACHRYLGKLSDKRRITVEYTLIAGVNDSETHAHELRDLLRDLPCKINLIPFNPFPNSGYERPSRNATLRFQKVLSDAGYVATVRTTRGDDIDAACGQLVGRVEDRTRRSQKYIPLQNINVSPDGRASV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_BRUA2
Sequence: MSNNTDLSPVHVIGGGLAGSEAAWQIAQAGVPVVLHEMRPVRGTDAHKTEQLAELVCSNSFRSDDAETNAVGVLHAEMRLAGSLIMACADAHQVPAGGALAVDREGFSQAVTARLEAHPLITIEREEITGLPPTEWGTTIIATGPLTAPSLAEAIAAETDADALAFFDAIAPIIHFDSINMDVCWFQSRYDKVGPGGTGKDYINCPMDKEQYEAFVAALIEGDKTDFKEWEGTPYFDGCLPIEVMAERGPETLRHGPMKPMGLTNAHNPTVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGSQTGIFKMIPGLENAEFARLGGLHRNTYLNSPVLLDNVLRLKSRQTLRFAGQVTGCEGYVESSAIGLLAGRFTAAEKLSQAAVPPPPTTAFGALLGHITGGHIVTNDEPGKRSFQPMNVNFGLFPPVDVPKPEGKRLRGKEKTIAKKRALSARALADCRNWLSLY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL4H_HUMAN
Sequence: MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A-like 4H, PPIase A-like 4H.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUNG_RUMCH
Sequence: MLKTKRKLTKAIGVALSISILSSLVSFIPQTNTYAAGTYNYGEALQKSIMFYEFQRSGDLPADKRDNWRDDSGMKDGSDVGVDLTGGWYDAGDHVKFNLPMSYTSAMLAWSLYEDKDAYDKSGQTKYIMDGIKWANDYFIKCNPTPGVYYYQVGDGGKDHSWWGPAEVMQMERPSFKVDASKPGSAVCASTAASLASAAVVFKSSDPTYAEKCISHAKNLFDMADKAKSDAGYTAASGYYSSSSFYDDLSWAAVWLYLATNDSTYLDKAESYVPNWGKEQQTDIIAYKWGQCWDDVHYGAELLLAKLTNKQLYKDSIEMNLDFWTTGVNGTRVSYTPKGLAWLFQWGSLRHATTQAFLAGVYAEWEGCTPSKVSVYKDFLKSQIDYALGSTGRSFVVGYGVNPPQHPHHRTAHGSWTDQMTSPTYHRHTIYGALVGGPDNADGYTDEINNYVNNEIACDYNAGFTGALAKMYKHSGGDPIPNFKAIEKITNDEVIIKAGLNSTGPNYTEIKAVVYNQTGWPARVTDKISFKYFMDLSEIVAAGIDPLSLVTSSNYSEGKNTKVSGVLPWDVSNNVYYVNVDLTGENIYPGGQSACRREVQFRIAAPQGTTYWNPKNDFSYDGLPTTSTVNTVTNIPVYDNGVKVFGNEPAGGSENPDPEILYGDVNSDKNVDALDFAALKKYLLGGTSSIDVKAADTYKDGNIDAIDMATLKKYLLGTITQLPQG
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Endoglucanase G, Cellulase G, EGCCG, Endo-1,4-beta-glucanase G.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
Protein: GTFD_STRMU
Sequence: METKRRYKMYKVKKHWVTIAVASGLITLGTTTLGSSVSAETEQQTSDKVVTQKSEDDKAASESSQTDAPKTKQAQTEQTQAQSQANVADTSTSITKETPSQNITTQANSDDKTVTNTKSEEAQTSEERTKQAEEAQATASSQALTQAKAELTKQRQTAAQENKNPVDLAAIPNVKQIDGKYYYIGSDGQPKKNFALTVNNKVLYFDKNTGALTDTSQYQFKQGLTKLNNDYTPHNQIVNFENTSLETIDNYVTADSWYRPKDILKNGKTWTASSESDLRPLLMSWWPDKQTQIAYLNYMNQQGLGTGENYTADSSQESLNLAAQTVQVKIETKISQTQQTQWLRDIINSFVKTQPNWNSQTESDTSAGEKDHLQGGALLYSNSDKTAYANSDYRLLNRTPTSQTGKPKYFEDNSSGGYDFLLANDIDNSNPVVQAEQLNWLHYLMNYGSIVANDPEANFDGVRVDAVDNVNADLLQIASDYLKAHYGVDKSEKNAINHLSILEAWSDNDPQYNKDTKGAQLPIDNKLRLSLLYALTRPLEKDASNKNEIRSGLEPVITNSLNNRSAEGKNSERMANYIFIRAHDSEVQTVIAKIIKAQINPKTDGLTFTLDELKQAFKIYNEDMRQAKKKYTQSNIPTAYALMLSNKDSITRLYYGDMYSDDGQYMATKSPYYDAIDTLLKARIKYAAGGQDMKITYVEGDKSHMDWDYTGVLTSVRYGTGANEATDQGSEATKTQGMAVITSNNPSLKLNQNDKVIVNMGTAHKNQEYRPLLLTTKDGLTSYTSDAAAKSLYRKTNDKGELVFDASDIQGYLNPQVSGYLAVWVPVGASDNQDVRVAASNKANATGQVYESSSALDSQLIYEGFSNFQDFVTKDSDYTNKKIAQNVQLFKSWGVTSFEMAPQYVSSEDGSFLDSIIQNGYAFEDRYDLAMSKNNKYGSQQDMINAVKALHKSGIQVIADWVPDQIYNLPGKEVVTATRVNDYGEYRKDSEIKNTLYAANTKSNGKDYQAKYGGAFLSELAAKYPSIFNRTQISNGKKIDPSEKITAWKAKYFNGTNILGRGVGYVLKDNASDKYFELKGNQTYLPKQMTNKEASTGFVNDGNGMTFYSTSGYQAKNSFVQDAKGNWYYFDNNGHMVYGLQHLNGEVQYFLSNGVQLRESFLENADGSKNYFGHLGNRYSNGYYSFDNDSKWRYFDASGVMAVGLKTINGNTQYFDQDGYQVKGAWITGSDGKKRYFDDGSGNMAVNRFANDKNGDWYYLNSDGIALVGVQTINGKTYYFGQDGKQIKGKIITDNGKLKYFLANSGELARNIFATDSQNNWYYFGSDGVAVTGSQTIAGKKLYFASDGKQVKGSFVTYNGKVHYYHADSGELQVNRFEADKDGNWYYLDSNGEALTGSQRINGQRVFFTREGKQVKGDVAYDERGLLRYYDKNSGNMVYNKVVTLANGRRIGIDRWGIARYY
What is the function of this protein?
Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.
What are the official names of this protein?
Glucosyltransferase-S, GTF-S, Dextransucrase, Sucrose 6-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 70 family.
What are the subcellular locations of this protein?
Secreted.