PharMolix/UniProtQA huggingface dataset:
Protein: GSA_SALRD
Sequence: MEVAPSDVDLRTSRRFYERAQHSIPGGVNSPARAFDSVGGTPLFIERAEGAYLEDADANEYLDYVGSWGPMIFGHAHPDVVEAVKDQAEASTSFGAPTEIEIEVADLVCDLVPSVEKVRMVNSGTEATMSAARLARGYTGRDKIIKFEGNYHGHGDFFLISAGSGAMTLGKPDSPGVTDGNAKDTLLAQYNDLSHVQRLVEANQGEVACIIVEPIAGNMGCIPPEPGFLEGLRELCDAHDIVLVFDEVMTGFRVAPGGAQERYGVIPDLTCLGKIIGGGLPVGAYGGKQEIMDYVAPTGPVYQAGTLSGNPLAMRAGHAILSKIAEEKDRIYDQLEDYAEALQKGTEHNLDALGLDYTTHQVGAMGSLFFTDAEVVDQDTAQTADTEAYAAYFHAMLEEGIYLPPSQFEAVFYGTCHGEDELETTLETQRRALKRVHS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_NOCSJ
Sequence: MAVPTFVDRVTLHVSAGRGGNGVASVHREKFKPLGGPDGGNGGPGGSVTLRVDPDVTTLLDYHHSPKRRAEHGGHGAGAHRNGAHGADLVLPVPDGTVVSDPQGHLLADLVGPGTELVVAQGGRGGLGNAALASAKRKAPGFALLGEPGDELEIVLELKVVADIGLVGFPSAGKSSLIAAISRARPKIADYPFTTLVPNLGVVSAGDTTFTVADVPGLIEGASEGRGLGHDFLRHIERCAAIVHVVDTASIEPGRNPVDDLDVIENELTRYGGLEDRPRLVALNKVDVPDGRDIAGFVVDELRQRGLRVFEVSAASGEGLRELTFAMAGIVEAARAAKPAVEATRIVLRPPSVDGSDAFTVTATPDGWRVRGEKPERWVRQTDFSNDEAVGFLADRLNRLGVETRLAEMGAEEGDAVLIGDPENAVVFDFKPGVDAAAEILSRRGEDQRFDESRPAARRRRAIEEAMADRAEGETRADVARRLDRPAREDGGAYGPQSYEIGGRDDPDWAEEDLGE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_STRT2
Sequence: MSSGKIAQVVGPVVDVAFATGDKLPEINNALVVYTDEEKSRRIVLEVALELGEGVVRTIAMESTDGLTRGLEVLDTGRPISVPVGKETLGRVFNVLGDTIDMEAPFADDAEREPIHKKAPTFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERSREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEDKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILEGKYDNLPEDAFRSVGPIEDVVAKAKAMGY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL21_PSET1
Sequence: MYAVFQSGGKQHRVTEGQTIRLEKLDVETGAAVEFDSVLLVADGEKIEIGVPFVNGGKITAEVVSHGRGEKIKVVKFRRRKHSRKQMGHRQWFTEVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RR19_CYAPA
Sequence: MARSLKKGPFIAHHLLKKVELLNTSGKTEVIKTWSRASTILPMMVGHTIAVHNGRQHLPVFITDQMVGHKLGEFAPTRTFKGHTKSDKKARR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
Cyanelle 30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: FUT5_PANTR
Sequence: MDPLGPAKPQWLWRRCLAGLLFQLLVAVCFFSYLRVSRDDATGSPRPGLMAVEPVTGAPNGSRCQDSMATPAHPTLLILLWTWPFNTPVALPRCSEMVPGAADCNITADSNVYPQADAVIVHHWDIMYNPSANLPPPTRPQGQRWIWFSMESPSNCRHLEALDGYFNLTMSYRSDSDIFTPYGWLQPWSGQPVHPPLNLSAKTELVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALDFCKACWKLQQESRYQTVRSIAAWFT
What is the function of this protein?
Catalyzes preferentially the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl-beta-D-glucosamine (GlcNAc) of an N-acetyllactosamine unit (type 2 chain) of an oligosaccharide, or a glycoprotein- and a glycolipid-linked N-acetyllactosamine unit via an alpha (1,3) linkage and participates in the surface expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.  Preferentially transfers fucose to the GlcNAc of an internal N-acetyllactosamine unit of a poly-N-acetyllactosamine chain acceptor substrate.  Also catalyzes to a lesser extend the transfer of L-fucose to the GlcNAc of a type 1 (beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl) or H-type 1 (alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc) chain oligosaccharide via an alpha (1,4) linkage.  Preferentially catalyzes sialylated type 2 oligosaccharide acceptors over neutral type 2 or H type 2 (alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-GlcNAc) oligosaccharide acceptors.  Lactose-based structures are also acceptor substrates.
What are the official names of this protein?
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5, 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5, Fucosyltransferase 5, Fucosyltransferase V, Fuc-TV, FucT-V, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RSAMI_BPPM6
Sequence: MDHAAWLNEETGEAAQEAYKYFMRPDPNQREFLGPIEEEDDPLTGMRAKFRMAKVGMVRNAKDEDKKEVKVYLGFNDVTYLPHIRIPNAKPLQGWYQDKHNDKRGSRARPCFSEAILTEPYGGYCTVGCAFCYVNSGFRGYRGTGLISVPVNYGEQVRNMLSKSRTSAAGYFSSFTDPFLPIEDVYHNTQQGAEAFVELGLPIFFLSRLSYPSWAIDLLKRNPYSYAQKSLNTGNDRDWHKLSPGAISLQDHIDEIAELRRQGIYTSIQVNPVVPGIVTHDDIRHLFERLAAVGNNHVIVKFVEAGYSWAPAMIERLHKRFGPERTKAFTDLFTENQAGAQKTIAEPYRVEAHQLYRKWATELGMTYATCYEYRRGKPGTGEPAWLSMGREMITADQCHGQRVPMFTRTDLDQPFQEVKECAPTGCLHCADDNEGKPRCGSELFGAAKALRSPDFKKIVEPTPPEEDGGERKIIPITQID
What is the function of this protein?
Isomerizes 5-N-alpha-glycinylthymidine (Nalpha-GlyT) into 5-Calpha-glycinylthymidine (Calpha-GlyT) as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-aminoethyl-2'-deoxyuridine (5-NedU) substitutes for about 30% of thymidines in the viral DNA (PubMed:34522950, PubMed:29555775).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
Radical SAM Nalpha-GlyT isomerase, gp53, rSAM glycinyl-thymine isomerase.
Protein: RS18_ANADF
Sequence: MARPDMGGPKSSGGFGGPRSGGGFGGGGYGGGGGGGGGYGGGGGGGFGGRGGDRGDRGDRDDRGGEEGGRRGFGRRKVCRFCADKTLKVDYKDQSQMKYFLTERGKIIPRRISGNCAKHQREVATAVKRGRMLAILPYTVGGM
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: BAME_PSEFL
Sequence: MQNTKLLLTSFTFVGLLALAGCSFPGVYKIDIQQGNVVTQDMIDQLRPGMTRRQVRFIMGNALLTDTFHADRWDYLYSLQPGGGERQQERVSVIFNGNDQLVSLSGDFMPGVSRDEALLGKDSGTNVTAPAQEAEKPKSEVPAKPGSLLDTIQKDIDNVETVPVPTPEPLDTSPQ
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity).  May have a structural role in maintaining the cell envelope integrity.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MRAZ_SHESH
Sequence: MFRGASAINLDTKGRIAIPKRYREPLHAEFNSQIVITVDFQSPCLLLYPFDEWSKIEAKLLLLSDTRATERAMKRLLLGYAHECELDGNGRILLPPPLRQYANLEKRAMLVGQLNKFELWDETAWQKQIEQSRETIQSEEFADNERLADFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYA_SYNS9
Sequence: MAAAASSSSAASLPQTGAEIRSAFLRFYEERGHKVMASASLIPEDPTVLLTIAGMLPFKPVFLGQQERPAPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWQLSTEVYGIDPKHLVVSVFREDDEAEQIWRDVVGVNPKRIIRMDEADNFWASGPTGPCGPCSEIYYDFKPELGDEGIDLEDDDRFIEFYNLVFMQYNRDAEGSLTPLANRNIDTGLGLERMAQILQKVPNNYETDLIFPLIQAAADCAGVDYHQLDDAGKTSLKVIGDHSRAVTQLICDGVTASNLGRGYILRRLLRRVVRHGRLLGINKPFLVMMGEASIALLKDAHPSVLERQEVILAELQREESRFLETLERGEKLLSEVLDSKPKQISGAQAFELYDTYGFPLELTQEIAEEQGLEVDLAGFEEAMEQQRQRAKAAAVSIDLTLQDAIDQVVATQKATAFQGYQRLEQPSCVQALVANGEPATSASAGDHVQIVLESTPFYGEGGGQVGDRGVLSGADVIVAIESVSRSRDVFVHAGRIERGQLTVGDAITAQVDRACRRRAQANHTATHLLQAALKQVVDPGIGQAGSLVDFDRLRFDFHAPQAVTTEQLGQIETLINGWIAEAHGLLVEEMAIDQAKAAGAVAMFGEKYADVVRVVDVPGVSMELCGGTHVANTAEIGLFKIVGESGVAAGIRRIEAVAGASVLGYLNERELVVKQLGDRFKAQPGEIVERVVALQDELKSTGKALIAAQAELAVAKSAALATKAVAIGSFQLLVERLDGVDGTGLQGAAQSLAAQLGDGAAVVLGGLPDPSDQGKVILVAAFGKDVIAAKQQAGKFIGTIAKLCGGGGGGRPNLAQAGGRDGAALAGALETARMELTAALQQQG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_GEOUR
Sequence: MKLIESIEEMQSTAINARQAGKTVALVPTMGYLHAGHASLMDEGRKRADILVASIFVNPTQFGAGEDFNTYPRDLEKDKLIAKAAGVDYIFAPKASDMYPTGYQTYVNVEKLTRPLCGASRPGHFRGVTTVVAKLFNIVMPHLALFGKKDFQQLTVIRRMAADLNMTVQIVGMPIVRESDGLAMSSRNAYLSQAERQSALCLSLALQSVRGAFRSGERSVEALRKLALDIINAEAFAVIDYVEFYHEATLTEVEQADDRTLVALAVKIGKTRLIDNCVLGED
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RU1C_PLAYO
Sequence: MPKYYCEYCDIYLTHSSPVGRRQHNQGRKHISAKIEYFQNLLREEGITPQNFLGFLGNQGYNNALANPMMNNFMPGNYNAYMKYNPMRNYHHSNRNPNYQHSIGMHNNKYSRAGYVPPGSNKYPNNHFHNNKRINNIQKPYNNFDNKNNNYNNKPITNSSYKNDKQDYRNNNENNDNMNSNHFSNYQMNKENANFVNKNNE
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IXTPA_BIFLO
Sequence: MQIVVATHNEGKLVEIRRILEEDLGADAENIELVSAGSLHLPDPVETGVTFQENALLKARAVAIRTGLPAVADDSGLIVDVMGNAPGILSARWAGAHGHDKANNALLLAQIEDIPDDKRTARFRCAAALVVPDTETGADVTGGVAADGITVHTTAADGSPAPVHARYAIKSETVELGDMPGRIIREARGVHGFGYDPLFVPDDQPAGRVSTEPDHEGEPLTSAEMTPAEKNAISHRGKALKALVPAIEALLH
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SYL_AROAE
Sequence: MQDKYTPAAVEATAQQHWESTQAFKVAEDAGKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLARYHRMRGFNVLQPMGWDAFGMPAENAAIQNNVPPAKWTYANIDYMKTQLKRLGFALDWSRELATCKPDYYRWEQWLFTRLYQKGLIYKKLGTVNWDPVDETVLANEQVIDGRGWRSGALIEKREIPMYYMKITAYADELLEALDTLTGWPEQVKLMQKNWIGRSEGVEVHFPYEVSTIGASGVLKVFTTRADTLMGATYVAVAAEHPLALQAAVNDPELAAFIEECRHGGVAEADLATMEKKGMPTGLRVVHPLTGEHLPVWIANYVLMGYGEGAVMAVPAHDERDFAFATKYRLPIRMVVRSTRDAYTDTVAPWQDAYAEQGRLVNSGKYDGLHFHDAIEAIAAELTAKGLGAKRTQYRLRDWGISRQRYWGCPIPMIHCADCGDVPVPDEQLPVVLPEDVAVTGRGSPLAKMPRFYECDCPKCGKPAKRETDTMDTFVESSWYFLRYASADNGQAMVDERVNYWAPVDQYIGGIEHAILHLLYSRFFTRAMRDEGLVNVSEPFTNLLTQGMVVAETYYRDADGGKKQWINPADVEVERDEKGRIVAAKLTADGAPVVIGGIEKMAKSKNNGVDPQALVDQYGADTARLFIIFAAPPDQQLEWSDSGVEGAYRFLRRVWSFGHAFVSEFRPQLPADRQLDAVQLPEALAAVRREIHVCLRQANYDFGKHQFNTVVSAAMKILNALEKAPRDVAAAHAQVAEEGLDILLRLLAPITPHVAHALWQDCGFTGDVLHASWPEPSEDALRQDEIDLVLQVNGKLRGSLRVAAGASNSAIEALALGSETAQKFMEGKPPRKVVVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_AGRRK
Sequence: MARNKIALIGSGMIGGTLAHLAGLKELGDIVLFDIADGIPQGKGLDIAQSSPVEGFDANLTGASDYSAIEGADVCIVTAGVARKPGMSRDDLLGINLKVMEQVGAGIKKYAPNAFVICITNPLDAMVWALQKFSGLPANKVVGMAGVLDSSRFRLFLAKEFNVSVEDVTAFVLGGHGDSMVPLARYSTVAGIPLTDLVTMGWLTAERLEEIIQRTRDGGAEIVGLLKTGSAYYAPAASAIAMAESYLKDKKRVLPCAAHLDGQYGVKDMYVGVPTVIGAGGIERIIEIDLNKAEKEAFDKSVASVAGLCEACITIAPSLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: PDXH_BURCH
Sequence: MTTLADLRINYSRASLDEADAAPDPFAQFDRWFKEALAAKLPEPNTMTLATVGADGRPSARIVLIKGVDERGFVFFTNYESRKGHDLAVHPQAALLFYWIELERQVRIEGRIEKTSAEESDRYFASRPLGSRIGAWASEQSAVIDSRATLEAREKAVSERYGDNPPRPPHWGGYRLVPDSIEFWQGRPSRLHDRLLYTRDAAAASGWTISRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL32_FUSNN
Sequence: MAVPKKKTSKAKKNMRRSHHALTAIGLVTCEKCGAPKRAHRVCLECGDYKGTQVLETAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NUOH_EHRCJ
Sequence: MSYYYNIFTDFISCISSGAVLLIKIMAVIISVMVSVAYLVYMERKVIGAIQLRQGPNVVGPFGLLQPFADAVKLIIKEHIIPFKSNKICFLIAPIITFTLALLGWAVIPFGADVIVNNGHEVIIPNVIANINIGVLYILAISSLGVYGIIIAGWSSNSNYAFLGAIRSASQMISYEVSIGLTIVTVLLATGSLKLGEIVVARHNMPYWIDLLLLPMACVFFISSLAETNRHPFDLPEAESELVSGYNVEYSSMPFALFFLGEYANMILINAMAVIFFFGGWYPPLNISFLYVIPGIIWFVLKIIVLLFCFIWIRATIPRYRYDQLMRLGWKVFLPISLLWVVLVSGVLLYTDSLPRNAYGIQYVHDLDQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TOP1_DROME
Sequence: MSGDVAAENSIHIQNGGSCEVVQSNGVTTNGHGHHHHHHSSSSSSSKHKSSSKDKHRDREREHKSSNSSSSSKEHKSSSRDKDRHKSSSSSSKHRDKDKERDGSSNSHRSGSSSSHKDKDGSSSSKHKSSSGHHKRSSKDKERRDKDKDRGSSSSSRHKSSSSSRDKERSSSSHKSSSSSSSSKSKHSSSRHSSSSSSKDHPSYDGVFVKPEPVSQQLMHSGSVDAFQMQQLGSYEAAAAGTNFNGNGNVAGANYKNGYEESIVDIKKEEESFNNLSQASSCDYSMSQFRADEPPFVVKHEQSYAEEDSTMNYNDHDDDADEMNDDEEDVPLAMRKRKQEATDRPDGGMDNDDDDDIPLLARKKVKKEKIKKESKEKSKKRVKEEPSDDYGNVKPKKKKMKKEPEPAVSPGKRQKAKAKVEEEEVWRWWEEEKRADGVKWSTLEHKGPVFAPRYERVPRNVRFYYDGKPLELSEETEEAATFYAKMLNHDYCTKEVFNNNFFKDFRKSMTPREREIIKDFRKCNFQEMFNYFQAESEKRKAASKEEKLIKKNENEALMKEFGFCMIDGHKEKIGNFRLEPPGLFRGRGEHPKMGMIKRRIQASDVSINCGKDSKVPSPPPGSRWKEVRHDNTVTWLASWIENVQGQVKYIMLNPSSKLKGEKDHIKYETARRLDKVIDKIRATYRDEWKSKEMRVRQRAVALYFIDKLALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRDEKKGKQLERLRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex (By similarity).  Introduces a single-strand break via transesterification at a target site in duplex DNA (By similarity).  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand (By similarity).  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils (By similarity).  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=During early cell divisions of developing embryos, it is detected in the nucleus at interphase then diffusely dispersed in the cytoplasm at metaphase.
Protein: RECF_XANOM
Sequence: MHVMRLSIHRLRRFQTVELHPASALNLLTGDNGAGKTSVLEALHLMAYGRSFRGRVRDGLIQQGANDLEVFVEWKEGGSAAGERTRRAGLRHSGQEWTGRLDGEDVAQLGSLCAALAVVTFEPGSHVLISGGGEPRRRFLDWGLFHVEPDFLALWRRYVRALKQRNALLKQGAQPRMLDAWDHELAESGETLTSRRMRYLERLQDRLIPVADVIAPSLGLSALTFAPGWKRHEVSLADALLLARDRDRQNGYTSQGPHRADWMPHFDVLPGKDALSRGQAKLTALACLLAQAEDFAFERSEWPVIALDDLGSELDRHHQARVLHRLVSAPAQMLITGTEIPPGLADAGALLHRFHVEHGQVD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_PSEPF
Sequence: MPLRSTFTRFFQLEAASGLLLIAAAILALIINNSPLSWLYNGLLDTPVVAQIGALKIAKPLLLWINDGLMALFFLLIGLEVKREVLDGQLSKPSQIVLPGAAAIGGMLVPALIYWFLNRDNPAALDGWAIPTATDIAFALGVLALLGKRVPVSLKLFLMTLAIIDDLGAIVIIAIFYSGELSTLSLGLAAACIAALVAMNRLGVVKLGPYMIIGLILWVCVLKSGVHATLAGVTLAFCIPLRTKNAEPSPLLTLEHALHPWVAYGILPLFAFANAGLSLSGVTVESFTHHVPMGIAVGLLLGKTLGVFGLTWLAVKTGIAALPQGANWGQVLGVAILCGIGFTMSLFVGSLAFVPGASEYAGMDRMGILTGSVFAALIGYAVTAAASRKNTALPS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMA_STAA1
Sequence: MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIIDASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVINEDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLVTVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGETLSIQDFAKLYEEKKKFPQLEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ACIET
Sequence: MALNQLSLSLQFARDAEATAHRATLPRHAVARWIRHALAVDAEITVRIVGAEEGQRLNREFRHKDYATNVLTFDYQQEPVAVADLVLCAPVVEREAREQNKTLEEHYAHLLVHGTLHAQGWDHETSEQDAQEMEVYETAILQELGFADPYAA
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_YERPS
Sequence: MTQDASPILTSLLDTDAYKLHMQQAVFHHYRHITVAAEFRCRSDELLGVYADEIRHQVTLMGQLALTSDEFIYLSSLPFFQDDYLHWLRDFRFKPEQVSVAVHDGKLDIRIAGLWCEVIMWEVPLLAVISEIVHRRRSTQVTTDQAVQQLRTKLEQFNALSADIDITHFKLMDFGTRRRFSREIQHTVVSTLKDEFPYLVGTSNYDLARTLALAPVGTQAHEWFQAHQQISPTLANSQRVALQVWLDEYPNQLGIALTDCITMDAFLRDFDLAFANRYQGLRHDSGDPIEWGEKAIAHYEKLGIDPMKKVLVFSDNLDLEKALFLYRHFYQRIKLVFGIGTRLTCDIPDVKPLNIVIKLVECNDKPVAKLSDSPGKTICQDPAFVDQLRKAFALPLVKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.