PharMolix/UniProtQA huggingface dataset:
Protein: ATRD_TAPPA
Sequence: MPVAVESAIPYPTPRKVDLAHHLSTEARIRQPNPIKSVWKAAQVRPGIINMGNGDPHHTLYPISSMNFIVPSLEGDHPVEAWRTGTSKTLVLSSHKDAPSTLSLRTAFAYGAGAGLPAVREALADLGARIHAPPNHTVCLSLGNADALTKCFRLFGDPDDSFLCEEFTFSAMTNAALALGIRWVPVRVDGGGLLPEDLERVMRCWDEKKQGKRPHVLYTVPCSQNPTGSTISLERRRRIYEVAHIYDIIIIEDDPYYFLQYDLQINQNTLKEHGYTRAMSEVLPRSFLSMDIDGRVVRLDSFSKVLAPGIRLGWITSSPFFADKLDMLTDSSTQHPHGLGQAYLAELLGPTGWGADGLMKWVHSLAREYERRRDLFVSVFDAKVAPTGCASAEVPQSGMFVWIQVHLETHPRFVVRTPDSGSDDEGDVLGAVMAAPGVLGEVARGGPITNTEQLMSELLRKLVESGVIMIPASTFAIVDRSGSTLSPIGDRANYLRATFVGTDETIRDGLTIFAQALEEFFNLK
What is the function of this protein?
The L-tyrosine:2-oxoglutarate aminotransferase atrD and the atromentin synthetase atrA catalyze consecutive steps to turn over L-tyrosine into atromentin, which represents the generic precursor molecule for the entire terphenylquinone and pulvinic acid family of pigments, which are widely distributed secondary metabolites in homobasidiomycetes (PubMed:18805498).  The first step is catalyzed by atrD which converts L-tyrosine in to 4-hydroxyphenylpyruvate (4-HPP) (PubMed:18805498).  Adenylation of two 4-HPP monomers by the atrA adenylation (A) domain, ester bond formation between monomers and atrA, and symmetric C-C-bond formation between two monomers by atrA leads to atromentin (PubMed:18805498).
What are the official names of this protein?
L-tyrosine:2-oxoglutarate aminotransferase atrD, Atromentin biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL5_CUPPJ
Sequence: MAARLQEFYKEKVVPKLIEQFGYKSVMEVPRITKITLNMGLGEAINDKKIIENAVGDLTKIAGQKPVVTKAKKAIAGFKIRQGYPIGAMVTLRGERMFEFLDRFVTVALPRVRDFRGVSGRSFDGRGNYNIGVKEQIIFPEIEYDKIDALRGLNISITTTAKNDEEAKALLGAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y1279_YERP3
Sequence: MQIWVDADACPNVIKEVLFRAADRTGMMVTLVANQPLKTPPSKFIRTVQVASGFDVADNEIVQRVEKNDLVITADIPLAAEVIEKGGIALNPRGERYTPDTIRERLNMRDFMDTMRASGIQTGGPNTLNQRDRQQFANELDKWLQQARNQAK
What are the official names of this protein?
UPF0178 protein YpsIP31758_1279.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: JIP5_BOTFB
Sequence: MFENLCTLPLSSELFTQALHPTEPILSVGLSSGHVQCFRLPAAEAAAEDEDGDPSVVSTGTSTIDTEWRTRRHKGSCRTLGYNHDGEVLYSAGTDSLLKAAASSTGQVTSKILIPNTNTDKLDPPTLLHALSPQTLLLTTDSCALHLYDLRDNSSFKSGKPAQTHYPHDDYISSLSPLPPTEMSTSGFSKQWITTGGTTLAVTDLRRGVLVKSEDQEEELLSSVFVGGLPARGKYGREKVCVGNGNGVITLWEKGVWDDQSERIIVDGGGKAGGESLDAMIAMPEELEGGYGGKCVVVGCGDGSVRIVRVGGTKGVVEDMKHDDIEAVVAVGFDVEGRLISGGGDTVKVWQEKVEEEEEEEEEEEQEDIEDNDDVMGGGGKHALERDSDDSDARADSSDEEDGGRKKRKKKKKGKKNQVGNGILKFKGME
What are the official names of this protein?
WD repeat-containing protein jip5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PANC_STAEQ
Sequence: MTKVITTINEMQSIVKQHQREGKTIGFVPTMGALHDGHLTMMKQSVSENDLTVISIFVNPLQFGPNEDFDAYPRQLDDDVAAVKKLQVDYVFHPSVDEMYPEELGIHLKVGHLAQVLEGAQRPGHFEGVVTVVNKLFNIVQPDYAYFGKKDAQQLAIVEKMVKDFNLPVHVIGIDIVREKDGLAKSSRNIYLTSEERKEAKHLYQSLRLAKNLYEAGERDSNEIIGQIAAYLNKNISGHIDDLGIYSYPNLIQQSKIHGRIFISLAVKFSKARLIDNIIIGDDYID
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPND_DROME
Sequence: MENGVEHGVDESGENQVLSSSDGEGDCDGDGEVEGEVLQPPPPPPLQITNDCVGEGVQAEEGERAPATTGAVDVTPDPGPPPTDGAAPVAILEDNMCDKDVDSDAGDEDNDDETKENYEGFNGTGRTVTLQTLMAANVLQPGLGLMTIEYLGQKFVGDLLADGKIKSHETETIFLTPSAWAMHCKRIINPDKKSGCGWASVKYKGKKLDAYKNTYLRKCALQKETPLDDCELDAERKTDTPEIVVKRTVFAHNTVSNRNVVHDANMLIESVPFTSVGKLQPFLITVNSSALLLADFHCHLTVREVCGYLGGTWDMNTHTLSITKTYPCRSTRFDRQRAGEVERDIQKMMIQDQLLLVGWYHSHPKFQAEPTLRDCDAQLDYQIKMRGASDLTYTPCVSLIISPYYDENPTLESVVKCIWIVPPNENRQSMEYGRPMLMQYSVLPDKEIPEEVRSEIQLCVDYYSQYRSEMVKFRNIYNNDVTYNEKLKNTLYPKFPSKQSDKALWNWICAVLDCEQEDDFIPPKTIKIIDNDDLEVKEEDKPVVLMDLSGDVKINPPKEEQFSEAMGGLEDSGRKAEEESNAQAEQKASELKVMSLQEQLCMPSGLNMNPVRMLSPLATPNPTSLPPVLPNLGAPVLPATPSQLLPPQVPAVTAPPAITPAVTTSALTSALNASPRDSPITIQSNSASPAKFEVPVRASPSPAKSDTSSHASTSRTRNSPAPSPGKFSVSDIARNSPSITPNKYEAAAAALVPPAAACLPTANDLMAASLAQLAGQLPPNFLQGDLAALFQQQRKDYGSSSLNQLAAAAAKVGGSKQSNASASSGLNDPNVAAAVAAYSNSFNMPLPTGVGIGGSGNSNAHSSSKSKSERSSKSSSSSSSSNSSSTSNSYKTKLMKELDELKNDPLKMSELIRSPEYAALLLQQAEALGATTLGTLGFGSDYSYLTGAGLGVPAANALTGGQSSNSSSSKSSKSSPAAAAAAALSADYNNLIQASKLLGYDSYMQQSKQSNDLNAFLQQQMAVAAASIPPPPQTASSGSSNSSSSKKQQQLQQQQHQQQQQQQQQQAAAQADYTALLQTYTKLFDPNNQFAAAMSSNKHMAGAHNELSALLSSGVGVGGGASGGGSKQKQKDIQSDMLNQLLQLEKQDSEIKALLYRQNKAAADLDALFATPSGAVVGAGSSANAMKSGSSAGNSGVSGMSSPSSLSNQAAYYNALAQEKMQDYAAFFQQQHGKYGIPDPLSKTTLAANNMFMTPSALFKIQQESLSAMMMKPPKSTTPSSARTRESSASPALERLTPTKSASSGGSGGGGSNSNSGGKYNFSAVDLAISSVPSNTPSPAPSDGSSGSSHRRPSPDIGRLYGELAPPGALLGSGGVPKKRMEFASVADLAAPPPAKMPKNNMGDDILNLSHD
What is the function of this protein?
Probable protease.
What are the official names of this protein?
MPN domain-containing protein CG4751.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67 family.
Protein: ALKB6_MOUSE
Sequence: MEEQDARVPALEPFRVEQAPPLIYYVPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTVLDFYEPRQPDDDVPMEQPRPPQRPITSLLVEPRSLLVLRGTAYTRLLHGISATRVDELDATSLPPNATACKSALPGAHLVRGTRVSLTIRRVPRVLRASLLLSK
What is the function of this protein?
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron.
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, Alkylated DNA repair protein alkB homolog 6.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRPA_XYLFA
Sequence: MHRIDETFRRLRAQSRKALIPFITAGDPSLEAAVPVMHALVRAGADVIELGVPFSDPMADGPVIQHSSERALQRGVGLAYVLQTVDVFRQSDAVTPVVLMGYLNPLEIYGIARFTQHAVACGVDGVLLVDLPPEEADEIRPIFSAAGLALIVLASPTTSASRLARLSGVAQGYLYYVSFSGVTGADRLDAQSAGDRLRGLRAQTQVPVVVGFGIRDAASAAVMAVDADGVVVGSALVTALSDAPDVDTACRRADAFLAPLRQALDAVK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: DAPD_BURVG
Sequence: MSQQLQQIIDTAWENRAELSPKAAPADVREAVAHAIEQLDKGALRVAEKIDGNWTVHQWLKKAVLLSFRLEDNAPMPAGGYSQFYDKVPSKFANYTAEDFAAGGFRVVPPAIARRGSFIAKNVVLMPSYTNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNLPSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CLOPE
Sequence: MNITVISVGKLKEKYLKQAIDEYSKRLSRYCKLEIIELPDEKTPDNASEKEELQIKEKEGKLILSKIKDNMHVIAMDLKGNEITSEKFSKYIENCGVMGNSNITFVIGGSLGLSQEVIKRADYKLCFSKMTFPHQLFRVMLLEQVYRAFRIMKNEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_ECO45
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVKDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTEMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_AZOVD
Sequence: MNLFDFFRERKKQSSASIAKERLQIIVAHERGQRSAPDYLPDLQKELIEVIRKYVNIDNDQVQVVLEDQGNCSILELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GCSPA_CHLL3
Sequence: MPFIVNTDADRESMLHATGVSSFDELIVDIPREVRLNKALELAPAADEMEVRSILESMAAANRSTADYVSFLGGGAYDHFLPSAIKAIVSRSEFYTAYTPYQAEVSQGTLQAIYEYQSLICRLYGMDVTNASMYDGATALAEAVLMAIGVNGRQKVVVAGKLHPWNSSVLKTYLEASDHSAVVQNVVEDGVGSIEVLKGLMDDTVAAVVVQQPNFYGCLEDVEAIGRLAHEHGALFIVSANPVSLGVLEAPGAYGADISVGEGQPLGSSQSFGGPYLGIFSVRQELVRKLPGRLVGMTKDSNGQDGFILTLQTREQHIRREKATSNICSNQALNALQAAVYLSLLGKQGLSEVAGQSLSRAHYLAGRIAAIPGFSIRYNAPFFNEFVVDTPIPPSEVVRKMLEKKVFAGCDLGEFGDEGLLVAVTEKRTKAQLDMFADALGELA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RBSD_ENTFA
Sequence: MKKTKVINSDISRVIAQMGHFDKLSIGDAGMPVPRTTEKIDLAVTNGVPSFMEVLNNVLEELAVQRIYLAEEIKTENPDMLAAIETRLPETPISFIPHTEMKQELNNCHAFIRTGEMTPYANILLESNVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_PSEMY
Sequence: MIAPRIALQFLTRLPVSLPGMPTPEQIGRSLLWYPAVGLLLGLLLWLAHLLLGQTPDVLQAAIILALWVGLSGGLHLDGLADTADAWVGGFGDPGRTLAIMKDPRSGPIAVVVLVLLLLLKFAALLSLLQAGQGIYLVLLPWLGRSLLPLLLATTPYVRAGGLGQALVDHLPRRQLPWVLGGHVAAMLLLGWGALIALATALALFVWLRRALMQRLGGTTGDTAGALLELAECAALLALALSL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OAR_PHOPY
Sequence: DDIKLSQQYDVLDLFKYMHQ
What is the function of this protein?
Putative receptor for octopamine.  Octopamine (OA) is a neurotransmitter, neurohormone, and neuromodulator in invertebrates.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Octopamine receptor, Octopamine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRF_MYCTO
Sequence: MTGFGLRLAEAKARRGPLCLGIDPHPELLRGWDLATTADGLAAFCDICVRAFADFAVVKPQVAFFESYGAAGFAVLERTIAELRAADVLVLADAKRGDIGATMSAYATAWVGDSPLAADAVTASPYLGFGSLRPLLEVAAAHGRGVFVLAATSNPEGAAVQNAAADGRSVAQLVVDQVGAANEAAGPGPGSIGVVVGATAPQAPDLSAFTGPVLVPGVGVQGGRPEALGGLGGAASSQLLPAVAREVLRAGPGVPELRAAGERMRDAVAYLAAV
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: DER_LIGS1
Sequence: MANPVVAIVGRPNVGKSTIFNRLAGERISIVEDTPGVTRDRIYARTEWLGHPFNLIDTGGIDIGDEPFLTQITEQAEIAIEEADVIIFVVSVKEGVTDADEKVARILYRTDKPVVLAVNKVDNPELRADIYDFYSLGFGEPIPVAGTHGIGTGDLLDKIIKEFPKDATNEEDDSIKFSFIGRPNVGKSSLVNAILGENRVIVSNIEGTTRDAIDTRFETEDGTKYTMIDTAGIRKKGKVYENTEKYSVLRAMRAIDRSDVVCVVLNAEEGIREQDKHVAGYAHEAGRAIVIVVNKWDTLKKDNKTMSDFENLIRQEFQYLSYAPIVFVSAKTKQRLDKLPELIKRVNDNHEQRISSAVLNDVVMDAIAHNPTPTDNGKRLRIYYATQVAIKPPTFVIFVNDPELMHFSYERFLENQIREAFDFEGTPIHIIERRRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RSMA_HERAR
Sequence: MKHIPRKRFGQNFLTDDGVLHNIILAIDPQPQDTMVEIGPGLAAMTRLLLDGVNQMHVVELDRDLVERLKKTFDPKKLIIHSADALQFDFSTIPVPAGSKLRVVGNLPYNISSPLLFHLAEMAPHVQDQHFMLQKEVVERMVAEPGSKTYGRLSVMLQWRYHMELMFIVPPTAFDPPPRVESAIVRMIPIEKPLPCDQTKLEQVVLKAFSQRRKVIRNCLAGMFSEADLIEAGINPQMRPETISLAQYVALANRL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_PSEA7
Sequence: MTIKSDKWIRRMAQEHGMIEPFVERQVRGADDSRVISYGVSSYGYDVRCAAEFKVFTNIHSAVVDPKNFDEKSFVDINSDVCIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLQSDEACEVSYKDRGGKYQGQRGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ZWILC_XENTR
Sequence: MWAERHRAAVELQQFLSSIYEQVKKGESLGPFQYKDDVQVHVVCDGHCKPLENFCSGSEVLYIMEKKPLTLEDNALDETENNEGISFYMSLQESPQPQAIPTMSARQFLTSYTLTHNPNMIQLNSGVPVKVLPPLWVRCDSSDAEGTCWLGAEPIKSNRNEITGMSFRTVTCAGPTADKSTFPSLDSLRQAHKERHYSSAMQTRGFAQYDLFGSNTVENSVIESQSSVTVDFVWNGVERILQLPPLTSAATLNIKVESGDLRSPVYSVYKELDFLLVLAEGLKTGVTEWPETSETKSAVDLVQHLLNDLKNKVDGLSTSVSKKDNEKIKSDTAAVDCSIQSFITERGDLDFAEMLWCKMRKSVSSYQDVVNCFSLVIQSLKHGEMHPWIHRGSSSTLSKLIQESYHGDMQSLSLTGLTPMRMLLEIGLDKMKKDYINCFIGQDLATFNYLDYFICTSVDLQEQVQRVKKLHHMLEVVVVCNAFLSLGHENLFPLTQSCLKYYKENPWNEQHVFQLPIRPSVISTFYQNSHPQTWRVEIISGHGQKEVKTTWQLTSRRPVDHVSFAVPDVPIDMTISGDNEELVYYPTQVSCSQVHFC
What is the function of this protein?
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.  Required for the assembly of the dynein-dynactin and mad1-mad2 complexes onto kinetochores (By similarity).
What are the official names of this protein?
Protein zwilch homolog.
What is the protein family that this protein belongs to?
Belongs to the ZWILCH family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: CAF1R_YERPE
Sequence: MLKQMTVNSIIQYIEENLESKFINIDCLVLYSGFSRRYLQISFKEYVGMPIGTYIRVRRASRAAALLRLTRLTIIEISAKLFYDSQQTFTREFKKIFGYTPRQYRMIPFWSFKGLLGRREINCEYLQPRICYLKERNIIGQCFNFRDLVFYSGIDSKCRLGKLYDSLKKNTAITVSNRIPFHDKTNDIIARTVVWDRNKHFSDSEIKVDKGLYAYFFFNDTYDQYVHHMYNIYYNSLPIYNLNKRDGYDVEVIKRRNDNTIDCHYFLPIYCDDMEFYNEMQVYHNNIVKPEMSVTLGLPKS
What is the function of this protein?
Positive regulator of F1 operon expression.
What are the official names of this protein?
F1 operon positive regulatory protein.
Protein: DEF_STRP7
Sequence: MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEIILGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEAYDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHRIKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ZUPT_CHLP8
Sequence: MSDSILFAFSLTLLAGLATGIGSIIGFLSKDVNPKMLTVSLGFSAGVMLYVSMIEIFVKAKDALSVELGDKAGYIWTVIAFFVGIFVIALIDKLVPAYENPHEMNTEKIIEESSAKDKAKLLRMGLFSALAIGIHNFPEGLATFMSGLSNPTLGISIAVAIAIHNIPEGLAVSAPIYFATKSRKKAFVLSFLSGLAEPIGAIAGFFLLRTLFTELTFGLVFASVAGIMVYISLDELLPTAEEYGEHHLAIGGLVGGMLVMAVSLLLFL
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSPL3_VITVI
Sequence: MSNLAETAPISSAHIPTLKLIDCSLRLCVIPLSVATIWLTVTNQQDNSIYGKLEFSNLTGLKYMVCISGISAGYALVAVVASWVRCLVNKAWLFFVSDQIMAYLMVTSGAAVLEILYLAYKGDRGVSWSEACSSYGRFCSRVNLALALHALALCCFLVLAVISAYRVFSMFEPPVSSKEVEEERAS
What are the official names of this protein?
CASP-like protein 2D1, VvCASPL2D1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MK_XENTR
Sequence: MELRAFCVILLITFLAVSSQAAKNKKEKGKKGASDCTEWTWGRCIPNSKDCGAGTREGTCKEETRKLKCKIPCNWKKAFGADCKYKFENWGECNATTGQKVRSGTLKKALYNADCQQTVEATKPCSLKTKSKSKGKKGKGKE
What is the function of this protein?
Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors.  Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups.  Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration (By similarity).  Inhibits mesoderm formation and promotes neural formation during development.  Plays a role in development of the neuromuscular junction (NMJ).  Has antibacterial activity against both Gram-positive and Gram-negative bacteria (By similarity).
What are the official names of this protein?
Midkine, MK.
What is the protein family that this protein belongs to?
Belongs to the pleiotrophin family.
What are the subcellular locations of this protein?
Secreted.
Protein: E2AB_ECOLX
Sequence: MSSKKIIGAFVLMTGILSGQVYAGVSEHFRNICNQTTADIVAGVQLKKYIADVNTNTRGIYVVSNTGGVWYIPGGRDYPDNFLSGEIRKTAMAAILSDTKVNLCAKTSSSPNHIWAMELDRES
What is the function of this protein?
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
What are the official names of this protein?
Heat-labile enterotoxin IIA, B chain, LT-IIA.
Protein: FH4_ARATH
Sequence: MAAMLMQPWPPFLPHLTLVFLTLILFFPNQSFSQSDSPRNIETFFPNDTITPPVQSPVLSPPQNPSSSSSDSDRGNILRAVLITAASTLLVAAVFFFLVHKCRRRRNRVGGVDNTLQPPVPPLAEAALAREGFTRFGGNVKGLILDENGLDVLYWRKLQQSQRDNKGGSFRKEIIHGDDEEKNVIYSKSKKKSGPVTETPLLRGRSSTSHSVIHNDNYRNATTTHPPHVKTDSFEFVKPDPTPPPPPPPPIPVKQSATPPPPPPPKLKNNGPSPPPPPPLKKTAALSSSASKKPPPAPRGSSSGESSNGQVKLKPLHWDKVNPDSDHSMVWDKIDRGSFSFDGDLMEALFGYVAVGKKSPDDGGDKKPSSASPAQIFILDPRKSQNTAIVLKSLGMTRDELVESLMEGHDFHPDTLERLSRIAPTKEEQSAILQFDGDTKMLADAESFLFHLLKAVPCAFTRLNALLFRANYYPEISNHNKNLQTLDLACTELRSRGLFVKLLEAILKSGNRMNAGTARGDAQAFNLTALLKLSDVKSVDGKTTLLNFVVEEVVRSEGKRCVLNRRTNRSFSRSSSSSISEVISKEEQEKEYLRLGLPVVGGLSSEFTNVKKAAAVDYDTVAATCLALTSRAKDARRVLAQSEGDNKEGVRFVKKMNEFLDSVEEEVKLAKEEEKKVLELVKRTTEYYQAGAVKGKNPLHLFVIVRDFLAMVDKVCVEIARNLQRRSSMGSTQQRNAVKFPVLPPNFMSDRSRSDSGGSDSDM
What is the function of this protein?
Might be involved in the organization and polarity of the actin cytoskeleton.
What are the official names of this protein?
Formin-like protein 4, AtFH4, AtFORMIN-4.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PURA_PROM3
Sequence: MSLANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDDKVLKLHLIPSGILYPETICLIGSGTVIDPKVMLKELDMLLENSIDISGLQLASTAHVTMPYHRLLDEAMEQQRGDQRIGTTGRGIGPTYADKSQRNGIRVLDLLDSQRLRERLRGPLQEKNRLLEQIYGVAPLDSEQVIEEYLGYGQRLAPHVVDCIQTIHQAARSRKNILFEGAQGTLLDLDHGTYPYVTSSNPISGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELEGSINEQLCDRGGEFGTTTGRRRRCGWFDGVIGRYAVAVNGLDCLAITKLDVLDELDEIRVCVAYELNGERIEHFPSSAEDFARCHPIFETLPGWQCTTADCRRLEDLPTTAMDYLRFLADLMEVPIAIVSLGANRDQTIVVEDPIHGPKRALLSA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.