PharMolix/UniProtQA huggingface dataset:
Protein: RBL_PICAB
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEESQFIAFVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHGGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEIWKEIKFEFEAVDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOC_POLNS
Sequence: MKALLDLFKQTQGDEQFDVIKIGLASPEKIRSWSFGEVRKPEAINYRTFKPERDGLFCAKIFGPTKDYECLCGKYKRLKFRGIICEKCGVEVTLAKVRRERMGHIELAAPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVVDPGMTPEGAMKRGQIMSEDEYIAKTEEYGDGVFTAIMGAEGIRDLLRSIDIDREVETIRADLKATGSDAKIKKYAKRLKVLEAFQTSGIKPDWMIMEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELRAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLAEMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLETLGIATTIKAAKKEVESQTPIVWDILEEVIREHPIMLNRAPTLHRLGIQAFEPMLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGEPSIVPSQDVVLGLYYATRDKINGKGEGMVFANITEVVRAYEAGQVELASRVAVRITEYEIVDKKAEGDARFAGKTKIYQTSVGRAILSEILPKGMSFEEINKPLKKKEISRLINTSFRKCGLRETVIFADRLLQSGFRLATNAGISVAIDDMLIPTSKERIITEASTKVKEYDKQFMSGLVTNQERYNNVVDIWGAAGDQVGKAMMDELSHVDVLDRNGKTVRQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLCDVTQDLVVIEEDCGATTGVTMKALVEGGEIIEALRDRILGRVCIGDIVHPDTQEVIVPNDTLLDEDHVDQIVALGIDEVKVRTVLSCLTRFGLCAKCYGRDLGRGGLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRALVASNIEAKSNGALKFSGTMRVVKNSRGEQIVISRSGEALIVDENGRERERHKVPYGATLLLKEDAAVKAGASLATWDPLTRPIISEYAGIARFDNVEEGVTVAKQVDEITGLSTLVVIDGKRRSAASKGVRPVINLIDDKGNDVMIAGTDHPVNIGLQVGALITVKDGQKVEVGEVLARIPIESQKTRDITGGLPRVAELFEARSPKDAAVLAKVTGTVSFGKETKGKQRLVITDMDGEANEFLIPKEKQVLVHDGQVVNKGEMIVEGPADPHDILTLKGIEELAIYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQVTDPGDTSFITGEQVERSKLYDENDRVIAEGKHPAQFDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKTDTLRGLKENVIIGRLIPAGTGLSYRRARKVREQFERDRAQMIAAEEEAMANMPVEIEAEVVALTGEADPS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TVP38_ASPCL
Sequence: MPAGYASTARALSLPMSPSGTPSPADDDIQSPPWGHLIPNRQNTPSPSIREATSFRDQITSQATRLLYRMKKTWRRLNFWQRVGAIGAVILAILLGLGFMIFTGQVFLWLEPVAETWEQSKLAFFVLWLCVFFVSFPPLVGWSTFGTVAGFIFGIWKGWLLYATATVLGSTCSFIVSRTVLSKFVNRMMERDKRFAALALTLKYDGLKLLCMIRLCPLPYSVCNGAVSTFPTVHPLMYGLATAIITPKLLVPAFIGSRIRILSEQKGEMSAGSKAVNICSIVLTISIGVFTGWYIYKRTLARAKELEAKERADIRRSLQADHAAHRPHGSFSEDPDVNTAASILARDEEERIGFNDFDDDNVDLVIDDESGSDNSSGQTRKHLQGSYRDEFTDNDSDVFRDGDGADSETYHLHTHVRPN
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein tvp38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: SRG3_CAEEL
Sequence: MSYEHCISGYTNFNENIHYFYQFAYLFTAICINYRILYVIWVSQRHFYRNQSFYNLYSVDCFTSVLAMSNELIFTRSFLYFPQLCVSFSEIVKNSPVFMRIYYCLLSYLIAIKPVIHIFIAVNRMSCVMFPVTYSQNWSQKLRIMLIVIFLAPFLVIWNVLISDNFIGYVNGGFGISYTRRVTWASLSLMQFTLIILTVLITMVTTTVTFYKMTTMKKRIKASERALCIAAALISVGFLLEAITQSFFAFFKEAPWLLDVMNYLRFATMDILFVGSPLVLLLVSDQFRGHVLGSRIGRTQRVSSINNTHSHIHHNTHHTMTRYSYFLWNVNK
What are the official names of this protein?
Serpentine receptor class gamma-3, Protein srg-3.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srg family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CASQ2_RAT
Sequence: MKRIYLLVVGLYLLSFSRAEEGLNFPTYDGKDRVVSLSEKNLKQVLKRYDLLCLYYHEPVSSDKVAQKQFQLKEIVLELVAQVLEHKNIGFVMVDSRKEAKLAKRLGFSEEGSLYVLKGGRTIEFDGEFAADVLVEFLLDLIEDPVEIVNNKLEVQAFERIEDQIKLLGFFKNEDSEYYKAFQEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVGFYEPFMDEPSVIPNKPYTEEELVEFVKEHQRPTLRPLRPEDMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFKPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDNEDEDDDGDNDNDDDDDDDDNSDEDNDDSDDDDDDDE
What is the function of this protein?
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle (PubMed:8042990).  Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits.  Can bind around 60 Ca(2+) ions.  Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction.  Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats (By similarity).
What are the official names of this protein?
Calsequestrin-2, Calsequestrin, cardiac muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the calsequestrin family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum lumen. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
Protein: ISCA_YERPN
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PSMG3_MOUSE
Sequence: MEDKPLVVSKQKTEVVCGVPTQVVCTAFSSHILVVVTQFGKMGTLVSLEPSNVANDISKPVLTTRVLLGQDEPLIHVFAKNLVAFVSQEAGNRAVLLAMAVKDKSMERLKALKEVIRLCQVW
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome.  May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes.
What are the official names of this protein?
Proteasome assembly chaperone 3, PAC-3, mPAC3.
What is the protein family that this protein belongs to?
Belongs to the PSMG3 family.
Protein: FLIW1_WOLSU
Sequence: MVYELKSPLLGFEEIKEFDLVEVDEMFAKIKAINNPSIEITLANPYALREYSFDIPAYIQALLDINAQSKVRVFCTVVIQNPIDESRVNFLAPLIFNDDNQTAAQIALSIKDYPDFSVADKIKNYVKE
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW 1.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VXIS_BPSF5
Sequence: MHGMGYDSRLDRLAATSWYPFFNNVTARGEIMEPYSLTLDEACDFLKISRPTAINWIRTGRLQATRKDPTKSKSPYLTTRQACIAALQSPLHTVQVSAGDGITEERKCHSSAEVKYGTPVSHCRTVKDLNSLLEQRTKGRRQNSMTS
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination.
What are the official names of this protein?
Excisionase.
Protein: URE1_YERPN
Sequence: MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRMADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDMIMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGNDNFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRPMFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPIATASMNQRYFFG
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SANBR_RAT
Sequence: MSRGCPENNNFLTNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMAAGEGPVETLATYIKSSLLDAQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGDSEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKDSKDCELPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINVNLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYFNPDSRNNAATLYRCCLCKKLLTRETERRISCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSAVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVLLHDQGENDDSLSCPTAKILDDLHKHKDVIAVPFLKDPVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEISKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDATRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVKASVPVTARQNSSDKNQSNIPQRHLFNYVHSNFIRNSQKLETSQMFIN
What is the function of this protein?
Negatively regulates class switch recombination or isotype switching in splenic B-cells.
What are the official names of this protein?
SANT and BTB domain regulator of class switch recombination, SANT and BTB domain regulator of CSR.
What is the protein family that this protein belongs to?
Belongs to the KIAA1841 family.
Protein: TX60B_PHYSE
Sequence: MSKPIIFLLTAFVVLTDLGATEDTEKVEVKAKPSKTSRGAIGQGFELHKIDLLSKELQGTGAQVFEELPVEECTTDNKLGTIQKDDTFYSNTESLYNSVASNSKIEPSLKGPFTLGTSVGAVTNNIVSEKSEIQGLSLNLKAYSMIHALKQDCINKKPLAKDLVSDFEALDREVKKPWLKPSWRKYKVFLEKFGTHIVRETMSGSSIYQYVFAKSSESFKQRDFKIKACLSLGGPTQVGKLGISACSDVSKKDVEESSGKEMVKKLVVRGGKSDTRVDLTGELSKNQINKFLKEATTDPSPIQYTFYPVWTILKARYIGKEHYAKATNLEQFYKGYLNFDCAYEKSEKGLELQKFELAEDSDPDAPTYVCKLGPEGCHSDDDCESDDLIYCACCGDSCIRYNNTVLLSTGDTKKVAFINDVDDEFRDHGCGRKGLKCKCKEENKKWGQSWSGDSDADAALRDINAMMLDQNRRDQAKRHHVKKGKSLH
What is the function of this protein?
Causes lethal toxicity to the shrimp Palaemon paucidence, and hemolytic activity toward sheep red blood cells.
What are the official names of this protein?
DELTA-alicitoxin-Pse2b, DELTA-ALTX-Pse2b, Toxin PsTX-60B, PTX60B.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: EIF3D_CHAGB
Sequence: MAEYTAGTSPLVDLINSLPDSDGTWGPPITNETTLNGVPYAPFSKSDKLGRMADWTDAKDGRDGRGRQQYNRNYRDQQVYGAGSASLFAPPAAEDEASFSVVSNVRDTGKTRFGRGAIFTRGRGQRGRGGQDTRGGGRQQFQRGGRGGQQYGGGGYSDRGGGRGGGARGRRFGWKDYDKPQRNRDASVNIRPDWKLLEEIDYNRLSKLNLDTDEGEDVDSYGFLYYYDRSYDKPPVKSAERKLAVVDRAVYNVTTSSDPIIQELAEKDEATIFATDSILSMLMCAPRSMYPWDIIIVRQGNKVFLDKRDNAALDMVTVNENAADAPLEASEGSKDVINQPGALAEEATYINHNFVNQVVLESSNQKVDMANENPFHSASEETEPPASKAYKYRRFDLSTSEETPTYLVVRTELDAVQKNPTSGEDQFVTVHALNEFDSKAQGSGGALDWRTKLVSQRGAVVATEMKNNSCKLARWTVQSILAKADVMKLGFVSRVTPKANDKHVILGCVGWKPKDFANQMNLQLSNGWGIVRTIADMCLQREEGKYVLVKDPNKNILRLYEVPANGLDDDDEGPEPEGVAEEED
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_MARN8
Sequence: MQQLNPSEISDIIKKRIEKLDISSEAKNEGTILSVSDGIVLIHGLADVMYGEMIEFANGTYGMALNLERDSVGAVVLGDYEGLAEGQKVRCTGRILEVPVGNELLGRVVDSLGNPIDGKGELGNSLTSPVEKVAPGVIARQSVDEPVQTGLKAIDTMVPIGRGQRELIIGDRQIGKTAVAIDAIINQKHTGIKCIYVAVGQKQSSIAAVVRKLEEHGAMDHTIVVAAGAADPAAMQFLAPYAGTSMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERASRVNADYVEQFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNSGIRPAMNAGISVSRVGGAAQTKIMKKLGGNIRLALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQNQYSPMTVAEMGTVLFAANEGFLDDVDVNKVVKFEAQLLDWMRSEQKELLDKIGPEGNFNDDITAGLKAALEKFKTTQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RUVC_KLEP7
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAATNQALPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAAQISETRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: YCX6_EUGLO
Sequence: MFFDLYEIILYILFFCVIFYGFLSFIELFYYLRDPRKRKKIIYIIIYIFCFLILMYILLIMDSYFIVNIIEFYQKYENGFKFFDNINRVILMHLEKGFNFFKSLF
What are the official names of this protein?
Uncharacterized 13.3 kDa protein in rpl23-rpl2 intergenic region, ORF105.
What are the subcellular locations of this protein?
Plastid.
Protein: RM53_DICDI
Sequence: MREKLNLLAKLKSVVYKFDPLNPNTRSIRSFIPLTTCKRSRQLAPECSISFDLGPQNTSPVIDIKFVNGTEKSIKTDTLELMSIVESIELLKKSIRIEEIEKMKTTETTLQDILQPVNKKKDTGAKANR
What are the official names of this protein?
Probable 39S ribosomal protein L53, mitochondrial, L53mt, MRP-L53.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VRPI_BPT3
Sequence: MEQREIKYLLTMEGNTESFEVPVFARSLEEATLQAEQYEDAGFVVTRIRPEVKA
What is the function of this protein?
Acts as an inhibitor of bacterial RNA polymerase.
What are the official names of this protein?
Bacterial RNA polymerase inhibitor, Gene product 2, Gp2.
Protein: DEOB_LIMRJ
Sequence: MSYKRVFVIVMDSVGTGAAHDAAKFDDVGSDTLGHVGEYYKGALKLPNLGKLGISNLRDTPIEGVPVADPAIGDYGKMEEISAGKDSMDGHWEMMGLPVMKPLSTFPNGFPQEIVDKLEKFSGRKVIVNKPYSGTEVIHDYGERQMETGELILYTSGDSVMQIAAHEDVIPVEELYKICEYARTLVNGPEYTVGRIIARPYVGPDKDHFTRTANRHDFSLKPIGETDMDRLRAAGYDVIGVGKINDIFSGEGIDKGYHNESNMDGMDHVDEVMKQDFTGFCFTNLVDFDAMYGHRRNPKGFGQALMDFDKRLGNVLDEMKPDDLLMITADHGNDPGFKGTDHTRENVPLLVYSPSMNKPNQSLGVRKTFSDLGATILENFNVEPVKGTSFYKEISND
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAR1_CAEEL
Sequence: MSSASVGKKPEHVNTPPGDNQQKSSKENQKSNKDKQSSNQPPGQIPHSTNSGTRKSSGSGLKTANLKHPARPSTESSTSSSHHRRPAQEMNGTSTATATGGGGTSGATTTASSGAPAASSGGSSARYSSSGRSHPTSGSSSSHARSTGQSGMSSRSAARRNDQDVHVGKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFSNTFSLGNKLDTFCGSPPYAAPELFSGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVINPQRRSSLDNIMKDRWMNVGYEDDELKPFIEPPKDQIDEQRIEKLIQIFQLGFNKAAILESVEKEKFEDIHATYLLLGERKSDMDASEITMAQSLLSHSSINVSSSLGQHPAGVITREHVTSSSASGSSASPSRYSRSSATATGASITAGSALASAANAQKHQQSSAAPSSGSSSSRRSSQNDAAATAAGGTVVMSGTRHGGVQMRAQPTSRQATISLLQPPSYKPSSNTTQIAQIPPLFNRNSTATSSAAQPSTGITGTRKIADPKGRIPLNSTAVQGHRTATGAVAANNGGIPSHRDHAQQQQYMNQLTSSTMMSKLINKTPAAGGTAATSSSSSSSATSTAPLQKSGSQISHAPTEPVIREDDDENNSENQNGNVPLIGGVGPQTSPAVQVPTEDATSSSDKEQQQQKASSETPKESKPSMIHQSPSMPPSQMMTAMESLKLSESGQTGGPTVATGGPPQRATSQQMSRSATTNSANMGASSGGAAAAASATNQLSGAPSSTGASSQQYHPKAPSSSSSSSTNPPHQHQLTHNASFSVTPSSYQIPTSTAVNVTSTGMPTSSSSSAFPRNTRNRQTFHGKTEKDKGGDDSSDEIGETPGNVSIGATGPSANNAEATIWSKLSKLTRRDHNRESMTQPVSGRAGTIGASQGQQTAAALAAIREQSGPIAPGAGQVAPSLPIHEGDVKPRSLRFTWSMKTTSSLAPDDMMREIRKVLDANGCDYEQRERYMILCVHGDPNTDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIGFKNIASKIAQELNL
What is the function of this protein?
Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis (PubMed:7758115).  Phosphorylates and restricts the asymmetry effector mex-5 (and possibly also mex-6) to the anterior cytoplasm of the zygote (PubMed:18842813).  Regulates mes-1 expression during early embryogenesis (PubMed:11003841).  Critical role in postembryonic vulval morphogenesis (PubMed:12490197).  Involved in the establishment of neuronal polarity (PubMed:20023164).
What are the official names of this protein?
Serine/threonine-protein kinase par-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Colocalizes with germ granules (P granules).
Protein: PSTS_ECOLI
Sequence: MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKWADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIGGVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRRADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGYVEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWPITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWKTNIKDSSGKPLY
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GSA_ESCF3
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYDVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPIGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_YERP3
Sequence: MSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQVNDGDMTIEKQGVELVVDPMSLQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: KLHL3_MOUSE
Sequence: MEGESVKPSPQPTAQAEDEEKNRRTVTVNAAHMGKAFKVMNELRSKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron (PubMed:25831548, PubMed:28052936).  The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation (By similarity).  The BCR(KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (PubMed:25831548).
What are the official names of this protein?
Kelch-like protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytosol.
Protein: FABZ_SALPK
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CHLAA
Sequence: MAVTFQHTPVLLTEVLTMLAPRPAGQYLDATVGGGGHALAVLQAAQPGGRLLGIDADPAALAATAARLQAAGLIEQAVLCHGSFADLATLAATAGFGAFDGILFDLGVSSYQLDTPERGFSFTADGPLDMRLDPTQGLTAADMVNRLSERELADIIFLYGEEHAARRIARAIVEHRRTQPFQRTAELAEVVARAVGGRHGRIHPATRTFQALRIAVNQELDRLRATLPQAVDLLAPGGRLAVISFHSLEDRIVKQFLRAEASGETPRLTIVTKKPIVPTAAEVANNPRARSAKLRVATRIG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.