PharMolix/UniProtQA huggingface dataset:
Protein: TOP1_LACLA
Sequence: MPTSTKSKTKTTTKKKTTRKRVTPGKNLVIVESPAKAKTIEKYLGRNYKVVASVGHIRDLKKSTMSVDIENDYEPQYINIRGKAPLINSLKKEAKAAKAVYLASDPDREGEAISWHLAHILNLPLEEKNRVVFNEITKDAVKNAFKEPRQIDVDLVDAQQARRVLDRLVGYSISPILWKKVKKGLSAGRVQSIALKLIVDRENEINAFIPEEYWSIDGEFKKGTKKFKASFWGIDGKKHPLKTNEDVIKVMERLDGPDFNVDKVEKKERRRNAPLPYTTSSMQQDAANKLNFRTRKTMMVAQQLYEGLTLGSQGHQGLITYMRTDSTRISPVAQSAAHNYIADQFGEKYSKHGSKVKNASGAQDAHEAIRPSNVFNTPDAIAKYLDKDQLKLYTLIWNRFVASQMVAAIFDTVKVNLSQNGVIFIANGSQVKFDGYLRIYNDSDKSNMLPEMEENETVKKANVKPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLETIQKRYYVRLSAKRFEPTELGEIVNKLIVEFFPNIVNTEFTAEMEKDLDEVEEGKRQWIEVVDQFYKPFAKELENAEEGMEKIQIKDEPAGFDCDVCGSPMVIKLGRFGKFYACSNFPDCRNTKAIVKEIGVKCPLCHEGNIIERKTKKNRIFYGCDRYPDCEFTSWDKPIGRDCPKSGHFLVEKKVRGGGKQVVCSNDECDYQEEKQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: URE1_MYCSK
Sequence: MTGLSRERYAALYGPTTGDRIRLADTDLVIEITEDRSGGTGLAGDEAVFGGGKVLRESMGQSRATRADGAPDTVITGAVILDHWGIIKADIGIRDGRIVAIGKAGNPDIMDGVHPDLVVGPSTEIIAGNGRILTAGAIDCHVHLICPQIMEEALGGGITTIVAGGTGPAEGSKATTVTPGAWHLARMLEALDTWPLNVVLLGKGNTVSAEAMWEQLRGGAAGFKLHEDWGTTPAAIDACLTVADAAGVQVNIHTDTLNEMAFVEDTLAAIKGRSIHAYHTEGAGGGHAPDIITVASHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPSVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVLRTWQTAHVMKRRRGALEGDGRADNNRARRYVAKYTICPAVAHGLDGEIGSVEVGKLADLVLWEPAFFGVRPHAVIKGGMIAWAAMGDANASIPTPQPVLPRPMFGAAPAAAAATSVHFVSPQAIEDGLADRIDVRRSLIAVADCRHVGKAQMPLNDAMPRIEVDPDTFTVRIDGDVWQEQPAAELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ECOUT
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PSBB_CARPA
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGLWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTRRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CCSA_AGRST
Sequence: MLFATLEHILTHISFSTISIVITIHLITLLVRELGGLRDSSEKGMIVTFFSITGFLVSRWASSGHFPLSNLYESLIFLSWALYILHTIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAAILIIRFRNNFHFFSKKKKNVLHKTFLFSDFYAKRSALKSTSVPSFPNYYKYQLTERLDSWSYRVISLGFTLLTIGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNQNWKGTNSALVASIGFLIIWICYFGINLLGIGLHSYGSFTLTPK
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL29_ACIF5
Sequence: MKAQAVQKLDLAGCQAQLLVLLEEQFRLRMQHATGQLAKTSRLRTVRRDIARVRTAITVKKEAHS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HSLV_BACC1
Sequence: MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLDIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_SHIDS
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EFG_AMOA5
Sequence: MAKDLKFLRNIGIMAHIDAGKTTTTERILYYTGLTHKIGEVHEGGAVMDWMEQEQERGITITAAATTTFWKYPTVQGQVTKDTQQYSINIIDTPGHVDFTVEVERSLRVLDGAVALFCAVSGVEPQSETVWRQADKYRVPRICFVNKMDRAGADFFNAVSEIKSKLGANPIPLQIPIGSEDTFKGVVDLIRNQAIIWNDEDLGMTYQVVPIPEDLKETVEEYRQKLMESVAEYDEVLLEKYFNDPNTITTEEIMVAIRKAVIDMSISPVLCGASFKNKGVQALLDAVCTYLPSPLDLPPVQGTNPDTEEKQIRKPDVNEPFAALAFKIATDPFVGRLAFMRVYSGKLDGSSYVYNNRTGKKERISRLMQMHANKQNPIDSIEAGDICAAVGFKDIRTGDTLTDEKNKIILESIVFPEPVIGYSIEPKKQADVDKLSMAISKLVEEDPTLHVETNEETGQTVMKGMGELHLEIIIDRLRREFKLEINQGAPQVAYKEALTSTIEHKEVYKKQTGGRGKFADIVFELGPREDGQMGLQFTNEIVGGAIPREFIPAIQKGFAAAMANGPLASYPVESMKVKLIHGSFHEVDSDSLSFELAARIGFKEAAKKASPVIMEPIMAVEVTTPDEFTGPVTGDLNKRRGIMRGMDAKGNTQVVKADVPLSELFGYVTDLRTITSGRAAATLTFSRYEQVPKQLADSIVEKVKGTANK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM04_CANAL
Sequence: MSLYSNIRTFSTRSIVLNRIKPLKFEDLTKIKLREPVVPRVANFEVSPDHPLWQFFPQGNKTKVAIRESEELDLDSREWSSAELRQKSFEDLHKIWYLTLKERNILSREVRLGESLGMGDFRQFNNVDRKLIKTQKRIKQVLLERQVAVERAQATMQDDIQKYLDDFKTRYVNCEADEVEDYHEKLVRLQYAIFGINPNLSLELLQDEETIDVNFVKGLSYIANLKVERHLKLNPQTEFELPLNGPVEELPFFLNDVEVAISQVKQLRDSGKSRMLHKIEVIPFLKQAIESHMQQEENIGGYEEEQNKN
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL27_RICTY
Sequence: MATKKAGGSSRNGRDSAGRRLGIKKSDGQYVIPGNIIVRQRGTKVHPGINVGLGKDHTIFSLIEGRVEFLTKQNHKIVNVKEIANV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PHNL_SOLFR
Sequence: MAESKPTPQSTFTGPIVVDPITRIEGHLRIMVEVENGKVKDAWSSSQLFRGLEIILKGRDPRDAQHFTQRACGVCTYVHALASSRCVDDAVKVSIPANARMMRNLVMASQYLHDHLVHFYHLHALDWVDVTAALKADPNKAAKLAASIAPARPGNSAKALKAVQDKLKAFVESGQLGIFTNAYFLGGHKAYYLPPEVDLIATAHYLEALHMQVKAASAMAILGGKNPHTQFTVVGGCSNYQGLTKDPLANYLALSKEVCQFVNECYIPDLLAVAGFYKDWGGIGGTSNYLAFGEFATDDSSPEKHLATSQFPSGVITGRDLGKVDNVDLGAIYEDVKYSWYAPGGDGKHPYDGVTDPKYTKLDDKDHYSWMKAPRYKGKAMEVGPLARTFIAYAKGQPDFKKVVDMVLGKLSVPATALHSTLGRTAARGIETAIVCANMEKWIKEMADSGAKDNTLCAKWEMPEESKGVGLADAPRGALSHWIRIKGKKIDNFQLVVPSTWNLGPRGAQGDKSPVEEALIGTPIADPKRPVEILRTVHAFDPCIACGVHVIEPETNEILKFKVC
What are the official names of this protein?
Periplasmic [NiFe] hydrogenase large subunit, NiFe hydrogenlyase large chain.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LUXS_CITK8
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDTITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVKEQNQIPELNVYQCGTYQMHSLSEAQDIARHILEHDVRINSNEELALPKDKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RS20_WOLSU
Sequence: MANHKSAEKRIRQTLKRTERNRYYRTRIKNITKAVKEAVASNDATKAEEALKVANKDLHKFVSKGILPKNTAARKVSRLHASVKKLSAQIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FDHD_WOLSU
Sequence: MRHTDRFVKKVVIERIGDQRVLAEEEDVVIKEERISLYLNGTKLMSMMSLPSDQDAHAVGFLMSEGVIEKIEDLKSVQISSDGSSVYVEALINHENITNLFKEKTLTSGCCVGVTGNLEGNVLRKFIATPMQISLERIWEGMEEFEMSSHLFHETGCVHKASLLLEDGSKITAEDIGRHNAIDKVMGKARLGRIDTEKAVLVVSGRLSMEMVVKAVMHNIPMIVSRAAATFLGIKTAQELGVTLVGFARGEKMNIYTHSGRVDLRACKRKRGVTLHAPNQSSSLLR
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG1_BACAH
Sequence: MNKKILFTGGGTAGHVMINMVLIPKFMGKGWGVEYIGSQNGIEKLLVQNVKYNSISTGKLRRYWDWENFKDPFKIIKGCIQSYKLMKRIKPDVIFSAGGFVSVPVVIGAWMNKVPVIIREPDSTLGLANKIALPFTTKLCTTFPQTGENVSNEKKVYVGPIVREEIERGNVLRGRSYCKFQQDKPVLLIMGGSQGAQWINDMVRGSLETLLLNFNIVHMCGKGKVDSSIGMEGYIQFEYIGEELPHILNMASVVVSRAGSTAIFELLFLKKPMLLIPLTNSSSRGDQVLNAEYFSRQGYAEVILQDRVSTNTFIHAVNKLNTNKERYIQNMNGYTKTNDEGIHQLIDIINEVVK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_ANOYA
Sequence: MTNIRKTHPLMKIINNSFIDLPTPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYLFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGALMLILILMMLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAFMPLLHTSKQRSMMFRPLSQCLFWILVADLIILTWIGGQPVEHPFIIIGQLASILYFMLILILMPLVSLFENNLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS4_FRASN
Sequence: MTLTLLPAVDVADGLAVRLVQGEAGTETSYGDPREAALAWQRDGAEWIHLVDLDAAFGRGSNRDLIAEVVRSVDVAVELSGGIRDDDSLDAALATGAARVNIGTAALEDPEWVRKAIDRVGDRIAVGLDVRGTTLAARGWTREGGELYEVLARLDADGCARYVLTDVRRDGTLTGPNVELLRAVTAATTRPVVASGGVSSLEDLRVIATVPGVEGAIVGKALYAGAFTLPEALAVAAEVPAAGAP
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFC2_DROME
Sequence: MPEEPEKTADDKRSHLPWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLGDSYKEAVLELNASNERGIDVVRNKIKMFAQQKVTLPRGRHKIVILDEADSMTEGAQQALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTEDGLEAIVFTAQGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKILAKLWKLGYSPEDIIANIFRVCKRINIDEHLKLDFIREIGITHMKIIDGINSLLQLTALLAKLCIAAEKH
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  Subunit 2 binds ATP.
What are the official names of this protein?
Replication factor C subunit 2, Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40, Replication factor C subunit 4, DmRfc4.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to all replicating nuclei, it is dispersed from chromatin in mitosis.
Protein: CDC16_ARATH
Sequence: MREEEIEKIRGVVRDCVSKHLYSSAIFFADKVAALTNDPSDIYMQAQALFLGRHYRRAFHLLNASKIVLRDLRFRYLAAKCLEELKEWDQCLLMLGDAKVDDDGIVYDAKDGNVIDFDKDGEDREINISSAICFLRGKAYGALQNRSQARQWYKAAIKADPLCYEALECLIESHMLTSEEESSLLSSLQFSPEDGWLSSFYSCLIKKYDKESTVELKFKKLENETSGSVSGSSMITLANNTDLLACKAEYYHQCCEYQKCFELTAALLEKDPFHLKCTLVHLAAAMELGNSNELYLMACNLVKDYPSKALSWFAVGCYYYCIKKYAEARRYFSKATGIDGSFSPARIGYGNSFAAQEEGDQAMSAYRTAARLFPGCHLPTLYIGMEYMRTHSYKLADQFFMQAKAICPSDPLVYNELGVVAYHMKEYGKAVRWFEKTLAHIPSALTESWEPTVVNLAHAYRKLRKDREAISYYERALTLSTKSLSTYSGLAYTYHLQGNFSAAISYYHKALWLKPDDQFCTEMLNVALMDECQNGVDSKVELC
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins.  The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation.  Involved in the control of endoreduplication.
What are the official names of this protein?
Anaphase-promoting complex subunit 6, Cell division cycle protein 16 homolog, CDC16 homolog, Cyclosome subunit 6, Protein NOMEGA.
What is the protein family that this protein belongs to?
Belongs to the APC6/CDC16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NTE1_ASHGO
Sequence: MVDGTYVNSSVEAISGEADTAAVAELANQMVMNFLYESSSWLAQSTGPFLWKGFRFLFLRLPSSLLVYLINGTVPFYLVVLGSVFTPIIVYLILRSRVLSAYSRLKGDNEDEVIDKKKQLVNDSEAMLMGGPDGKRRSGFSSYLDEFLSAIKIFGYLDKLVFHELTKSMRTQRLEQGEVMLLDDSVGFAIVVEGGLHIYHKIAHSQGSTRESMPLPEDRSFDSNEDDLTINGERFQLLNKVKAGNPVSSLVSILKLFTDNHTPTVVDSSKSSPKQSAQVPIRQLISPFLDGNVERNKATLNMKQVPTAEYEIPSAERAGSNVSSFTQQLYESMLPKDHAAEDVREPLPEIVAYAASDCAIAVIPASSFKRLMVKYPRSASQIIQVILTKLYRVTFQTAHSYLGLTKEIMHTEVVLNNSTNFELPYYLQEAILRKIKNGSKESSVQESIHRATLRSKNVHAHNSPTPNKISRHIALESRDQYNPGDLLSNVPLSRKGSKTASSSSVSIPRISSLRHQKEAASSPLATLRRLEGNDSQNFAPLSSSSPMSVSEKPSVVGGGAHDNISQISFSSALEETEESSWRMALVESMFGYLGITNESIMPPTEDLLFLNNRASSGSSVCSVSSYSHPQTINQDLFRCLSPELVRTKKKAPRQKYTEEMPINVDFNTAKEEFAEGLETLFIPSGATIVEQNGNNKGLYYIVSGELLVCWKNEEDNIEYVLYTVKPGGIAGYLASLIGFKSFVSLRAKTDLYVGFLPIEVLERLCDKYFMIYLKIAETLTKLLSPKILKLDYALEWIHLEASETLFNQNDPANAIYVVLNGRLRQLHQKSKNEERLSRPTTQRKKRKDDNQPNVQVVGEYSQGCSFGEVEVLTAMNRVSTVVAVRDTELARIPRTLFEVLALEHPSIMIRVSRLVAHKILQRSSDIREPTKIVNSANGYRYDFNLTIPPSAGTSSWGNNSDGGSISYKTITILPITYGLPVEEFANKLVSTFRQVGRSTIGLTQCTTLKHLGRHAFDKLANLKQSGYFAELEELYELVVYIADTPVKSSWTSTCISQGDCILLLADASSDPEIGEFERLLINNRTTARTELLLLHPERYVEPGLTHKWLRKRTWVHQHHHMQFVSSQNPSERVDSKAPPIPGAPPNLIGRLKKRERLNQLTKRTQENFARLLPDSIKLTVENISMKYIQKKQKYYTPVSAHKNDFLRLARILSGQAIGLVLGGGGARGISHLGILKAIEEHGIPIDMIGGTSIGSFVGGLYAKDYDLVPTYGRVKKFAGRIGSIWRMLSDLTWPVTSYTTGHEFNRGIWKAFGDIRIEDFWIQYYCNSTNITESMQEIHTFGYAWRYVRASMSLAGILPPITDNGNMLLDGGYLDNLPVLEMKARGCKTIFAVDVGSVDDRTPMDYGDSLNGFWIVLNRWNPFSKHPNVPSMAEIQMRLGYVASVNALEKAKTTQGVVYFRPPIEDYATLDFAKFEEIYQVGTAYGATFLHELEQNGKLPRIPGNEPANGPGIHLLHRRNSI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MNME_FRAP2
Sequence: MYTKDTIVAVATPQGNGGIGIVRISGSDALSIAEKLTKKRLKPRYATFCNIYNINEIIDHGIVIFFNSPNSYTGEDVVEIQAHGNPFILNLIIKATLEYGARMANAGEFTERAFLNNKLDLTQAEAVADIINASSETAAKSAAKSLQGDFSKEINNLLEKLIYLRMYVEASIDFPEEEINFLEDQKIHNSLQDIYKTILDVKNSCKQGAILVEGITLILVGKPNAGKSSLLNALAGKESAIVTSIAGTTRDIVKEHIQINGVPMHIIDTAGLRSSDDIIESEGIKRAIKKIQEADQILFVTDDYTNSQVKFSDIKDIIPEFYHQIPKDIDITYVHNKIDLLKEVPLNHDNHIYISAESNIGIDKLKDHILAKVGYTTQNESIYTARERHVTAIDNAFDHIKLAKEQLELGNGELLAEELLIVQEHLNSITGEFSSDDLLGEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOSB1_XENTR
Sequence: MTTETFVKDVKPGLKNLSVLFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDLGNFIQPGDIIRLTKGYASLFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYIAQQSQNKQAQAESGTGTNSHNSSSPAPPASDLENGNGSNSSGPPTHQSTAPTHSTSGRITRSQPNHSIPGAPNSVSNGKEPRRTGKR
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA.  The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOSS-B family. SOSS-B1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage.
Protein: DAPEL_BACC1
Sequence: MVVSKFVQIRRDLHKIPEIGFKEWKTQQYILDYIGTLSNEHVEVKVWRTGVIVKVKGRNPEKVIGYRADIDGLPITEETGYEFASVHEGMMHACGHDLHTTIGLGLLTAAVTERIDDDLVFLFQPAEEGPGGALPMLESEELKEWKPNIILGLHIAPEYPVGTIATKEGLLFANTSELYVDLKGKGGHAAYPHTANDMIVAASHLVTQLQSVISRNVNPLDSAVITIGKITGGTVQNIIAEKSRLEGTIRTLSVESMSRVKSRIEAIVAGIEASFQCEAVIDYGAMYHQVYNHEALTREFMQFVSEQTDMKVITCTEAMTGEDFGYMLQEIPGFMFWLGVNSEYGLHHAKLKPDEEAIEKAIVFLDQYVKWKGTRK
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: ISPG_MYCBP
Sequence: MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMGEQDPGATPSGSPIVTVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.