PharMolix/UniProtQA huggingface dataset:
Protein: UCP3_HUMAN
Sequence: MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRALMKVQMLRESPF
What is the function of this protein?
Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism (PubMed:21775425, PubMed:36114012).  Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis (PubMed:9305858, PubMed:11171965, PubMed:12670931, PubMed:12734183).  However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity (PubMed:11707458).
What are the official names of this protein?
Putative mitochondrial transporter UCP3, Solute carrier family 25 member 9, Uncoupling protein-3, UCP 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VATA_CLOBB
Sequence: MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVVTTGEPLSVELGPGLIESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDFKPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIKEIKAGSFTVTETIAIVETEKGDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTVTQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEPVSQSTLRIVKVFWGLDAQLAYQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGIDALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGVYLNDILAMEDLKDRIARSKYIHEDDLEKMDQIVVDLKNAIDNLINKGGVANA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PSAC_PARMW
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y3672_VIBC1
Sequence: MARKNQKAPWEPEEEIIWVSKSEMKRDMEELQKLGEELVGLKPAVLDKFPLSEDLREAVADAQRFKNEARRRQLQRIGKLMRYEDPEPIQAALDKIRNKHSQATAALHKLEALRDRVVEEGDKAIDDVMELYPEADRQRLRQLARQAAKEKKAGKPAKSYREIFQILKAFEEEM
What are the official names of this protein?
UPF0307 protein VIBHAR_03672.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: L14BA_XENLA
Sequence: MSSGTPYIGSKISLISKAQIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPAPPREEVYEYIIFRGSDIKDITVCEPPKASHALPQDPAIVQSSLGSAPAASYQPSVPYSPFRGMPTYSQLAATSLLSQQYAASLGLEKLGSPTASAGASSSCSSPSPQPVAPEPDVPAEPPQLSQNAGYPSIPVRKSPMVEQAVQTGPLENQAQKKVQQAKGAPVGQRGVRQSGPQSQPAPLNVPPPAAPVLGTINDENRRPPRRRSGNRRTRNRSRGQNRPTTVKENPIKFEGDFDFETANAQFNREELDKEFKDKLNFKEEKPEKEGEEKTDSGVETQNSDGNPEEDPLGPNTYYDRSKSFFDNISSEMKSRRTTWAEERKLNTETFGVSGRFLRGRSFRGGFRGGRGSAAPRRNQTTQRAGTGRV
What is the function of this protein?
May be involved in the storage of translationally inactive mRNAs and protect them from degradation (By similarity).  Plays a role in control of mRNA translation (PubMed:18631138).
What are the official names of this protein?
Protein LSM14 homolog B-A, RNA-associated protein 46, xRAP46, RNA-associated protein 55B-A, RAP55B-A, xRAP55B.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
Protein: LEUC_TRIV2
Sequence: MSKGTLFDKVWDLHTVGTLPSGLTQLFIGLHLVHEVTSPQAFAMLRERGLKVLFPERTVATVDHIVPTENQARPFVDRLAEEMIQALEQNCQENNITFYNIGSGNQGIVHVIAPELGLTQPGMTIACGDSHTSSHGAFGAIAFGIGTSQVRDVLASQTLSLSKLKVRKIEVNGTLNPGVYAKDVILHIIRTLGVKGGVGYAYEYAGTTFEQMNMEERMTVCNMAIEGGARCGYVNPDQVTYDYLQGRDFAPQGADWEKAVAWWESIKSDADAEYDDVIVFNAADIPPTVTWGITPGQGIGVNQLIPQPEELLEEDRFVAEEAYRYMDLYPGQPIKGTKIDVCFIGSCTNGRLSDLQEAAKIAKGRHVAEGVKAFVVPGSERVKKAAEAEGLDKIFEAAGFEWREPGCSMCLAMNPDKLEGRQISASSSNRNFKGRQGSASGRTLLMSPAMVATAAIQGEVADVRELL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CYB_VARVV
Sequence: MTNTRKNHPLMKIMNNSLIDLPAPSNISSWWNFGSLLGACLTLQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFLCLFIHIGRGLYYGSFTLLETWNVGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGINLVEWIWGGFSVDKATXTRFFAFHLILPFIIMAXVMVHLLFLHETGSNXPLGTPSDSDKIPFHPYYTIKDXLGLLLLXLLAMTLVLFSXDLLXDPNNYMPANPLNTPPHIKPEWYFLFAXAILRSIPNKLGGVLALFFSILILAIIPLLHTAKQQSMIFRPLSQYLFWILIANLFTLTWIGGQPVEHPYIVIGQTASILYFSLILIIMPLVNLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: P2C02_ARATH
Sequence: MSSSVAVCNSPVFSPSSSLFCNKPLNTSPAHETLTLSLSHLNPPVSSTSPSAASPTSPFCLRLLKPPAKLGFGSDSGPGSILKRKRPTTLDIPVAPVGIAAPISNADTPREESRAVEREGDGYSVYCKRGKREAMEDRFSAITNLQGDPKQAIFGVYDGHGGPTAAEFAAKNLCSNILGEIVGGRNESKIEEAVKRGYLATDSEFLKEKNVKGGSCCVTALISDGNLVVANAGDCRAVLSVGGFAEALTSDHRPSRDDERNRIESSGGYVDTFNSVWRIQGSLAVSRGIGDAHLKQWIISEPEINILRINPQHEFLILASDGLWDKVSNQEAVDIARPFCKGTDQKRKPLLACKKLVDLSVSRGSLDDISVMLIQLCHLF
What are the official names of this protein?
Probable protein phosphatase 2C 2, AtPP2C02, Protein phosphatase AP2C2.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: CHED_CLOTE
Sequence: MHTMEVKEYRVGIADLNVAKSPDRIITVGLGSCIGIALYDRINGVGGLLHIMLPDSTQFKNVSNPLKFPDLGIIIMTDKMKEKGANIRNIKAKISGGASMFNFSDKSMVMDIGRRNIEAVRKKLKELSIPIVAEEVGGNKGRTMTLDTSNGIVQIKTVGVGMKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: GLPK_KORVE
Sequence: MRLPYILALDQGTTSSRAIVFDQDGVVRSVAQREFTQIFPQAGWVEHDPEEIWASQISVAVEALSRAELRSRHVAAIAITNQRETAVVWDRETGRPVYNAIVWQDRRTAGFCDQLKAAGHEEFVQQRTGLLIDSYFSGSKVRWILDNVPQARSLAERGRLAFGTVDSWLIWKLTSGKLHITDVSNASRTMLFNIHTCQWDEELLRLLEIPASMLPEVRSSSEVYGTVQTSLGLESIPIAGIAGDQQASLFGQRCTSPGMAKNTYGTGCFMLQNTGERAVPTSNRLVTTVAWKIGDVVEYALEGSVFIGGAVVQWLRDGLRLVRSSGEFQELANSVKDNGGVYVVPAFVGLGAPHWDQYARGGIFGITRGTTDGHVARAALESIAYQVADLLDAMQRDTGVPLPELRVDGGAAANETLLQFQADIMGVPVVRPSVTETTALGAAFLAGIAVGLWSDPQVIAKMPVEQKRFEPRMGSAEALALRHQWEKALSRVKGWEEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TRPA_THENN
Sequence: MKGFIAYIPAGFPDLETTRKVLLALNDLRITGVEVGVPFSDPVADGPVIQLAHSVALRNGVTMKKILEMLREISVDYELYLMSYLNPIVNYPEGKDRLLDELRRLGVKGLIIPDLPLREVKNIEISFPIVPFVAPNTRDEDLEAINTIRAPFVYYISRYGVTGEREDLPFAEHIKKVKKKIALPLFVGFGISRHEQVRKVWEIADGVIVGSALVRIMEESKRQEIPQKVVARVKELIGEK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LARC_THESQ
Sequence: MRILYLDPFSGISGDMFLGLLVDLGVDPEKIKSRLEKLNVEFEFVVKKENKKGVTATKVDVVFPGKEHHEDHIVSDHDHHHHHGRHLSEIVEVLSRLEDPLKEKAIRMFETLAEAESKIHGLSKEKVHFHEVGAMDAVIEIAGAVAGLELLGVEKVFCGTVNTGSGFVMTEHGRYPVPAPATAELLKGIPIYVDQKVRTELVTPTGAVILKSLVDEFRTPILRVEKVGYGAGTMDLEIPNVLRGYLGYIEPSERTGDVLIETNVDDMSPQLFGHLMERLFEAGAKDVFFTPIYMKKNRPAVKVSVLCHESKKDEILKLLFKESTSIGARVFYPEKVEATRTVKTVKTEYGEIPVKIASFDSEIVNISPEYEACKKIAQEKGIPLKEVYRAVCKSVSEVRDDV
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: DNA2_MOUSE
Sequence: MEPLDELDLLLLEEDGGAEAVPRVELLRKKADALFPETVLSRGVDNRYLVLAVETSQNERGAEEKRLHVTASQDREHEVLCILRNGWSSVPVEPGDIVHLEGDCTSEPWIIDDDFGYFILYPDMMISGTSVASSIRCLRRAVLSETFRGSDPATRQMLIGTILHEVFQKAISESFAPERLQELALQTLREVRHLKEMYRLNLSQDEILCEVEEYLPSFSKWAEDFMRKGPSSEFPQMQLSLPSDGSNRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKMKYKVMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGWLLYLKTGQMYPVPANHLDKRELLKLRNWLAASLLHRVSRAAPGEEARLSALPQIIEEEKTCKYCSQIGNCALYSRAVEEQGDDASIPEAMLSKIQEETRHLQLAHLKYFSLWCLMLTLESQSKDNRKTHQSIWLTPASELEESGNCVGNLVRTEPVSRVCDGQYLHNFQRKNGPMPATNLMAGDRIILSGEERKLFALSKGYVKKMNKAAVTCLLDRNLSTLPATTVFRLDREERHGDISTPLGNLSKLMESTDPSKRLRELIIDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFKRLERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQLYADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILDLPSREHESLSHILGDCQRD
What is the function of this protein?
Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion.  Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1.  Also involved in 5'-end resection of DNA during double-strand break (DSB) repair: recruited by BLM and mediates the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by the presence of RPA.  Also involved in DNA replication checkpoint independently of Okazaki fragments processing.  Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities.  While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is subject to debate.  According to various reports, the helicase activity is weak and its function remains largely unclear.  Helicase activity may promote the motion of DNA2 on the flap, helping the nuclease function (By similarity).
What are the official names of this protein?
DNA replication ATP-dependent helicase/nuclease DNA2, DNA replication ATP-dependent helicase-like homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: HEMN_PSEAE
Sequence: MLDTIRWDADLIRRYDLSGPRYTSYPTAVQFHEGIGPFDQLHALRDSRKAGHPLSLYVHIPFCANICYYCACNKVITKDRGRSAPYLARLVREIEIVSRHLSREQVVEQLHFGGGTPTFLSPGQLRELMSQLRTHLNLLDDDSGDYGIEIDPREADWSTMGLLRELGFNRVSLGVQDFDMEVQKAVNRMQTPEETRTIVEAARTLQYRSINLDLIYGLPKQTPDSFARTVDEVIALQPDRLSVFNYAHLPERFMPQRRINADDLPSPGQKLEMLQRTTEQLAAAGYRYIGMDHFALPDDELASAQEDGTLQRNFQGYTTHGHCDLVGLGVSAISQIGDLYSQNSSDINDYQTSLDNGQLAIRRGLHCNSDDRVRRAVIQQLICHFELAFEDIETEFGIDFRSYFAELWPDLERFAADGLIRLDAKGIDITSSGRLLVRSICMLFDRYLPSLNRQRFSRVI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STREM
Sequence: MGSDYVLSILVDKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVGSYINVSLYRAIDKVKVFQGDLVAFDGDILTIDYLDKTRHKTVEIPYQAVAKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_HERAR
Sequence: MRASRFFISTLKEAPSDAEIVSHKLMMRAGMIKRLGSGIYTYMPIGLRVIRKVEAIVREEMNRAHAIELLMPLVQPAELWQETGRWDKMGPELMRVKDRHGREYAIQPTSEEVVTDVVRSEIKSYRQLPLNFYHIQTKFRDERRPRFGLMRGREFTMKDAYSFDRDAEGLKRSYQIMFDAYVKIFNRFGLQFRAVAADNGAIGGSGSHEFHVIADTGEDAIVYCPTSDYAANMEAAEAIAPAVPRAAATQTLTKTATPGKAKCEDVAALLNLPLAQTVKSIVLTVEKEDKGVVSKEIWLLLLRGDHELNEVKAAKIPGLTDYRFANEAEIVEWFGTPPGYLGPINTKKPVKVVVDRTVAAMSDFVCGANEVDFHFTGVNWGRDLPEAMVLDLRNVVEGDPSPDGKGVLAIQRGIEVGHVFQLGTAYSEKMKATYLDENGKPQLIQMGCYGIGVTRIVGAAIEQNFDDRGIIWPAALAPFEVVLCPMGYDRSESVKTETDKLYEALLAAGVDVILDDRGERPGAMFADWELIGAPHRIVIGERGLKEGALEYKGRRDADATAVALDDMLAFVQARLAA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_CLOPE
Sequence: MKFSKMHGNGNDFIVIEDLNNEYLGKEGEIAQKMCHRRFGIGADGILIVRKNENCDIEMVIINSDGSYAAMCGNGIRCFAKYVYEKGIVKKDVLDVLTGDGVKRIFLEIENDKVKTINVNMGFGDFKPKNIPALCDEEIIEKKVSVGNGNFEITSLLMGVPHTIIFEEEKYPIECGRDIEKYELFPQGTNVNFCKVIDRNTMEVRTWERGAGPTLACGTGNCASVIAANKLGLVDKEVKVIVPGGELKVNIEDDGVKMIGNASFICDGTYLF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOI_ARATH
Sequence: MAVQAHHMNIFSQFISPNRDCVKFQENMNHGEFEFTGGEVPLITGESFAVEPLAAKANFNKAESGLSYNFTVPPLSTKRQRDFQFSDSNAPVKRRSVAFDSSSPSLINVELVSQIQNQQQSEIDRFVAQQTEKLRIEIEARQQTQTRMLASAVQNVIAKKLKEKDDEIVRIRNLNWVLQERVKSLYVENQIWRDIAQTNEANANTLRTNLDQVLAQLETFPTASAVVEDDAESSCGSCCGDGGGEAVTAVGGGCKRCGEREASVLVLPCRHLCLCTVCGGSALLRTCPVCDMVMNASVHVNMSS
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the regulation of pathogen and abiotic stress responses by facilitating degradation of MYB108/BOI.  Attenuates cell death by preventing caspase activation.  Has no effect on the stability of the DELLA proteins.  Not regulated by MYB108/BOI.
What are the official names of this protein?
E3 ubiquitin-protein ligase BOI, Inhibitor of apoptosis (IAP)-like protein, AtILP, Protein BOTRYTIS SUSCEPTIBLE 1 INTERACTOR, AtBOI, RING-type E3 ubiquitin transferase BOI.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADD_BACVZ
Sequence: MKKIGIFGGTFDPPHNGHLLMANEVLHQAELDEIWFMPNKIPPHKQNEDFTDSRHRVEMLKLAISSNSGFKLELAEMDRKGPSYTYDTVRLLKERHPNDKLFFIIGADMIEYLPKWYKLDELLTLIQFIGVRRPGYHIETPYPLLFADVPEFDVSSTMLRERLKAKEPTQYLMPDKVRQYIEENDLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PYRB_PSYCK
Sequence: MSNSIDSQSLPTVSPTDYARFDPDTIHEKLDASLSRPQLNTDGSIRHFLGIEGLNKAQLQAIIAKAESFFDDKGQLINRPELEGYTVMNLFFEPSTRTRTTFEVAEKRLGANVLNIDIERSSTKKGESLRDTLWNLQAMTADIFVVRHSASGAAHFMATEVTPDIAIINGGDGWHAHPTQGMLDMLTIHREAPRPFEELSVAIVGDIKHSRVARSDISALQTLGVKDIRVCAPRTLLPKGIERFGVQVYENMNECVTDCDVIMGLRIQNERIGSPLLASSSEYYKHYGITPERVALAKPDALVMHPGPMNRGVEIASSVADGAQSVILKQVNNGIAIRMAVLSLAMEGQRAHQAAGH
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: YUAW_ECOLI
Sequence: MADLNLIPENCQRCEDEESITAKAVIPPHPASSYVETYVGRAVPTGQYRIDRPSGPLTSLYDKGGRLDIANYCTVSLF
What are the official names of this protein?
Uncharacterized protein YuaW.
Protein: SUCC_BACFN
Sequence: MKVHEYQAKEIFSTYGIPVERHALCHTADGAVAAYHRMGVNRVAIKAQVLTGGRGKAGGVKLANNDRDVYQYAQTILEMTIKGYPVTKILLSEAVNIAAEYYISFTIDRNTRSVTLIMSAAGGMDIEEVARQSPEKIIRCSIDPLIGVPDYLAHKFAFSLFEQAEQANRMATIIQDLYKAFIEKDASLAEINPLVLTPVGTLLAIDAKMVFDDNALYRHPDLQKLSEPTEDEKLEAIAKERGFSYVRMDGEIGCMVNGAGLAMTTMDMIKLYGGNPANFLDIGGSSNPVKVIEAMRLLLDDKKVKVVFINIFGGITRCDDVAIGLLQAFEQIQTDIPIIVRLTGTNGNMGRELLRKNNRFQVAQTMEEATKMAIESLKKESI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SYP_THET2
Sequence: MAKEKGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALQAKGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEQGQAVLASRLGGKETLPLAALPEALPGKLVAFHEELYRRALAFREAHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_LIMF3
Sequence: MSKQEAVSELTKQQAQAELTPLREQLKKWGAEYYEQDNPSVEDYVYDRAYQRLVEIEQRFPDLVVPDSPTQRVGGAAESQLNKVTHEIPMLSMGDVFSLAELADFNRRQQDNSDVKVDFDYNLELKIDGLSLSLVYENGRLVQGSTRGNGTIGEDVTENVKTIKSIPQVLPEPLSLEFRGECYMPKEAFVKLNERREAEGQPVFANPRNAAAGSLRQLDPKVTAARQLDTFMYYVPDYQALGVTTQAQALEKMRALGFAVNPNYRVVHSQAELTAYIEEYTKKRDQLPYGIDGIVEKVNDLATQVALGNTVKVPRWEIAYKFPPEEQATVVRDIEWTVGRTGNVTPTAVMDPVQLAGTTVSRASLHNPDYLVEKDIRLGDTVLLHKAGDIIPEISRVIIEKRPADSKPYEVPTTCPECGADLVHLDDEVALRCVNPMCPAQIKEGLAHFASRNAMNIDGLGPKIIEQLWDKGMVKDVADLYRLEAAQLLTLPKFGEKSISNLLTAIANSRHNSCERLLFGLGIRHVGAKVAQLLAAEFKSVDALMAADAATISAVDSIGPIIGDAVATYFQNEQVHQLIAELKEVGVNMDYLAPTTSATESAEWAGKRVVLTGKLTKMTRGQAQEWLSARGASVTGSVSKKTDLLIAGEKAGSKLEKAQTLGIEVWDEDRFDQAMKEEN
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PIMT2_PELPD
Sequence: MRYRCPMNCPSLRNQEYRREIMISEQLMGRGIRDPAVLAAMRQVPREAFVDQGMRELAYEDHPLPIDGGQTISQPYIVAYMTEALELSSSDRVLEIGTGSGYAAAVLSRIVHTVYSVERLEELARGARQRLESLGYNNVEVFEGDGTLGWPEHAPYDAIVVTAGAPAVPKPLLRQLVVGGRLVIPVGASSFLQNLIRVRRQGEDDYRSEELCGVRFVPLVGAEGW
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase 2, L-isoaspartyl protein carboxyl methyltransferase 2, Protein L-isoaspartyl methyltransferase 2, Protein-beta-aspartate methyltransferase 2, PIMT 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.