PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_VESOH
Sequence: MSQRDFYEILGIAKNTDVKQIKKAYKRLAMKHHPDRVKDNKELAEKKFKEIQKAYAILSDTQKRQAYDQFGHAGINGNAGATSGTSFSSSGFGDIFGDIFGGGSQQSNNRGSDLRYDLEIDLKEAAQGTTVKIRIPKNETCDTCSGTGAKPGTSVKTCLTCGGAGQIQIQQGFFAVQRPCNACSGTGQRIESTCNNCHGKGVVHKQKTLSVKIPAGVDTGNRIRLSGEGEAGIRGGLSGDLYVQIHVKKHAIFERQDSDLYCEVPIDFATAVLGGQVEVPTLDNKLNIKVPAGTQTGKLFRLRSKGITHLQHGGSGDVICKVKLETPINLSKKQQDLLQKFSNSCGKKHHPESNSFFGKMKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR0_ECOLX
Sequence: MSRVFAYCRVSTLEQTTENQRREIEAAGFAIRPQRLIEEHISGSVAASERPGFIRLLDRMENGDVLIVTKLDRLGRNAMDIRKTVEQLASSDIRVHCLALGGVDLTSAAGRMTMQVISAVAEFERDLLLERTHSGIARAKATGKRFGRPSALNEEQQLTVIARINAGISISAIAREFNTTRQTILRVKAGQQSS
What is the function of this protein?
Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.
What are the official names of this protein?
Transposon Tn2501 resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: MSHC_RHOJR
Sequence: MQSWSETAVPSVPGQGPPLRLFDTADRQVRPVTPGRTATMYVCGITPYDATHLGHAATYLTFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWVVLGMRETALFREDMEALRVLPPRDYIGAVESIGEVIEMVEKFVASGAAYVVDDPEFPDVYFRANATEQFGYESGYDRETMDKFFAERGGDPDRPGKEDPLDALVWRAVRPGEPSWPSPFGPGRPGWHIECSAIALNRIGSGFDVQGGGSDLIFPHHEYSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLVFVSKLRGEGVDPAAIRLGLLSGHYRQDRPWTEQLLADAHTRLQLWKDAAALESAPSATDTIARLRQHLADDLDTPKALDALDGWARRALDHGGSDTNAPSEFAAAVDALLGVRLRRP
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: PDXS_METM5
Sequence: MKKLGTDLLKRGFAKMVKHGVVMDVTNVEQAQIAEDAGAAAVMALERVPADIRVQGGVARMSDPEMILEIKDAVSIPVMAKARIGHYVEAQVLESIGVDMVDESEVLTPADEVNHIDKRAFTAPFVCGARNLGEALRRIDEGAAMIRTKGEAGTGNVVEAVKHMRAVNEGIARVVGYKEMGLEAELIQMARNELKVPMELISEVAELKRLPVVNFAAGGIATPADAALMMQMGCDGVFVGSGIFKSGNPEVRAKAIVEATYNFDKADVIGEVSKNLGEAMVGINIDEIPEEKLLAKRGI
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: PEM4_PHACH
Sequence: MAFGSLLAFVALAAITRAAPTAESAVCPDGTRVTNAACCAFIPLAQDLQETLFQGDCGEDAHEVIRLTFHDAIAISQSLGPQAGGGADGSMLHFPTIEPNFSANSGIDDSVNNLLPFMQKHDTISAADLVQFAGAVALSNCPGAPRLEFMAGRPNTTIPAVEGLIPEPQDSVTKILQRFEDAGNFSPFEVVSLLASHTVARADKVDETIDAAPFDSTPFTFDTQVFLEVLLKGTGFPGSNNNTGEVMSPLPLGSGSDTGEMRLQSDFALARDERTACFWQSFVNEQEFMAASFKAAMAKLAILGHSRSSLIDCSDVVPVPKPAVNKPATFPATKGPKDLDTLTCKALKFPTLTSDPGATETLIPHCSNGGMSCPGVQFDGPA
What is the function of this protein?
Catalyzes the oxidation of Mn(2+) to Mn(3+).  The latter, acting as a diffusible redox mediator, is capable of oxidizing a variety of lignin compounds.
What are the official names of this protein?
Manganese peroxidase H4, MP-I, Peroxidase manganese-dependent H4.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ligninase subfamily.
Protein: NDT2_ARATH
Sequence: MIEHGNSTFDYRSIREVAANAGAGATAGAIAATFVCPLDVIKTRLQVLGLPEAPASGQRGGVIITSLKNIIKEEGYRGMYRGLSPTIIALLPNWAVYFSVYGKLKDVLQSSDGKLSIGSNMIAAAGAGAATSIATNPLWVVKTRLMTQGIRPGVVPYKSVMSAFSRICHEEGVRGLYSGILPSLAGVSHVAIQFPAYEKIKQYMAKMDNTSVENLSPGNVAIASSIAKVIASILTYPHEVIRAKLQEQGQIRNAETKYSGVIDCITKVFRSEGIPGLYRGCATNLLRTTPSAVITFTTYEMMLRFFRQVVPPETNRSDDRRREEERKNLVSRRGEEEDKDLGLRESQTQSNKISTPHIPLGSK
What is the function of this protein?
Mediates the NAD(+) import into chloroplast.  Favors the NAD(+)(in)/ADP or AMP(out) antiport exchange, but is also able to catalyze a low unidirectional transport (uniport) of NAD(+).  Transports NAD(+), nicotinic acid adenine dinucleotide, nicotinamide mononucleotide, nicotinic acid mononucleotide, FAD, FMN, TTP, TDP, TMP, UTP, UDP, UMP, CTP, CDP, CMP, GTP, GDP, GMP, 3'-AMP, ATP, ADP and AMP, has low transport activity with cAMP, NADH and alpha-NAD(+), and has no activity with NADP(+), NADPH, nicotinamide, nicotinic acid, adenosine, thiamine mono- or diphosphate, inorganic phosphate, CoA, folate, NaCl, malate, malonate, citrate, fumarate, aspartate, glutamate, S-adenosylmethionine, lysine, arginine, and ornithine.
What are the official names of this protein?
Nicotinamide adenine dinucleotide transporter 2, mitochondrial, AtNDT2, NAD(+) transporter 2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CNCG_BOVIN
Sequence: MSDNTVLAPPTSNQGPTTPRKGPPKFKQRQTRQFKSKPPKKGVKGFGDDIPGMEGLGTDITVICPWEAFSHLELHELAQFGII
What is the function of this protein?
Participates in processes of transmission and amplification of the visual signal.  cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
What are the official names of this protein?
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma.
What is the protein family that this protein belongs to?
Belongs to the rod/cone cGMP-PDE gamma subunit family.
Protein: INSL3_ECOLI
Sequence: MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLLRLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAVTGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLDCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELAKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN
What is the function of this protein?
Involved in the transposition of the insertion sequence IS186.
What are the official names of this protein?
Putative transposase InsL for insertion sequence element IS186C.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: P53_TETMU
Sequence: MEEENISLPLSQDTFQDLWDNVSAPPISTIQTAALENEAWPAERQMNMMCNFMDSTFNEALFNLLPEPPSRDGANSSSPTVPVTTDYPGEYGFKLRFQKSGTAKSVTSTYSEILNKLYCQLAKTSLVEVLLGKDPPMGAVLRATAIYKKTEHVAEVVRRCPHHQNEDSAEHRSHLIRMEGSERAQYFEHPHTKRQSVTVPYEPPQLGSEFTTILLSFMCNSSCMGGMNRRPILTILTLETQEGIVLGRRCFEVRVCACPGRDRKTEETNSTKMQNDAKDAKKRKSVPTPDSTTIKKSKTASSAEEDNNEVYTLQIRGRKRYEMLKKINDGLDLLENKPKSKATHRPDGPIPPSGKRLLHRGEKSDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity).
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MOCOS_ASPTN
Sequence: MTEAIINEGSPLGYSQGYSEDIDAIRQREYPMLSDTTYLDHAGTTLYAKSLIDSFSRDLTTNLFGNPHSLSASSQRTTQRVDDIRLRALRFFNADPEHFDLVFVANATSAIKLVADALRDSAHGFWYGYHVDAHTSLVGARELAQAGSRCFTTDEEVEAWIAQLDADRTGAAQLFAFPAQSNMNGRRLPLRWCGRIRDRTKETATTYTLLDAASLVATSPLDLSDVSAASDFTVLSFYKIFGFPDLGALIVRKSAGHIFAQRRFFGGGTVDMVLTQDTQWHAKKRSVHEILEDGTLPFHNIIALDSALDTHARLYGSMGNVSTHTRFLARTLYDRLAALRHFNGERVVHFYMGRSPDFADASAQGPILAFNLRSSQGGWIGKSEVERLASVKSLQIRSGTLCNPGGTASQLGWSGADMLRHFSAGLRCGDDHDVMDGRPTGILRVSLGAMSNLRDVEAFVAFVEEFYVEKTPNVCSVVPSAADDSLQAGFYVESLAVYPIKSCGAFKVPDGQRWEIRREGLAWDREWCLVHQGTGAALNQKRYPRMALIRPHIDLARGVLRVVCGEASSEQKTLEISLRREDASLVTTSLCQNAAKPSTVCGDQVVVQVYSSTAVSSFFSTFLDVPCTLARFPPQSTTRYTRRSLHSRSSTAALRRQRPVEESSMPGSFPSDTPLSRTPEPPPILLANESPILLISRSSVNRLNETIKASAKKAVAADVFRANIVVAENLPHQLANTERPYIEDRWESFTVGPDRLQFDVLGSCQRCQMVCIDQCSGERRDEPFSTLAKTRKVGSQIVFGRHAAVADGVDGISRTVMVGDVVRPWYPE
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: RL39_METMP
Sequence: MAGNKPLGKKIRLAKALKQNRRVPMFAIARTKGSVKQHPKMRHWRRKNLKK
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: PTH_STRPN
Sequence: MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP3_HUMAN
Sequence: MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
What is the function of this protein?
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity).  Binds gangliosides and stimulates ganglioside GM2 degradation.  It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A.  It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3 (By similarity).  Has cholesterol transfer activity (PubMed:17552909).
What are the official names of this protein?
Ganglioside GM2 activator, Cerebroside sulfate activator protein, GM2-AP, Sphingolipid activator protein 3, SAP-3.
What are the subcellular locations of this protein?
Lysosome.
Protein: ISPG_RHIME
Sequence: MSSAFDFEPQPRRASVAVDVGGVIVGGGAPVVVQSMTNTDTADIDATVAQVAALHKAGSELVRITVDRDESAAAVPKIRERLLRLGIDVPLVGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFAEIIEMAIRYDKPVRIGVNWGSLDQELLTRLMDANQANGSPLTAQQVMRETIVQSALLSAELAEELGLPRSRIILSAKVSGVQDLIAVYAMLAARSVHALHLGLTEAGMGTKGIVASSASLGILMQQGIGDTIRISLTPEPGGDRTREVQVAQELLQVMGFRQFIPVVAACPGCGRTTSTVFQELAQKIQEDIRASMPVWREKYPGVEALKVAVMGCIVNGPGESKHADIGISLPGTGEMPAAPVFIDGQKALTLRGPKIAEDFQLLVADYIEKRFGHGQAAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FTSQ_HAEIN
Sequence: MNILKRKTPQNIRFGEQKPKYYFHIRAFAVLLGVFFLLGVYFNWQSILEKMDDKPISAFALVGQNTFTTADDIKESLLKMGELKGFWGQDVAPIQEQIEALPWVKGAIVRKMWPNRLSIWVSEYQPVAFWNQNQFVTLDGIVFQLPSVRLTAKNLPYLGGPDYQSLKVIETWNQIYINLKSNNIMAKGINIDDRGAWQVQLDNDIVLKLGRGDWKSKLERFVTIYPQIDVPENKKIDYIDLRYTAGAAVGMVDR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.  May control correct divisome assembly.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ARLY_HISS2
Sequence: MALWGGRFTQATDKRFKDFNDSLRFDYRLAEQDIEGSIGWSKALVTVNVLTQQEQQVLENALSELLIEVRSNPQKILQDDAEDIHSWVESKLIDKVGNLGKKLHTGRSRNDQVALDIKMWCKQRVTELQHSVRELQRKLVETAEHNQHVVMPGYTHLQRAQPITFAHWCMAYVEMLDRDYGRLQDAYQRMNTCPLGSGALAGTAYAIDRDLLAQDLNFAMATRNSLDSVSDRDHIIELLSTASLSMAHLSRFAEDMIIFNSGEADFVELSDRVTSGSSLMPQKKNPDACELIRGKVGRVVGALTGMLMTVKGLPLAYNKDMQEDKEGIFDALDTWQDCVDMATFVLEDIKVSVERTKEAALKGYSNSTELADYLVAKGVPFRDSHHIVGETVVYAIKVHKGLEDLSIKEFHQFSNAIEEDVYEILSLQSCLDKRCAKGGVSPLRVAEAIAEAKKRFK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STAAR
Sequence: MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVKGKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMAVDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLNIETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSAFEQAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQTKEEVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQKITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLVGGKQTYSFQDLPQFTPEIFMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKNEYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFEEKFPEIKLYSLL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLAH_ESCF3
Sequence: MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGVDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLEHYFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTAHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: UTP25_VANPO
Sequence: MARHSGTSEGPKKRGRTELRSIRRPNRSQHSKHDQQVVHESENEDSLESSSDDDEDIAQAEAENSDRKEKVYGALLTILNSEHPERKKHKSHSTDFVKEIDEQEEIEQGMASESEEEDEENDEEESNEGDEEEEEEPTDQLDTFESHFNDVSQDLVDDISAGFKDKQIKYKSMKYSLDKKESAIFGKPLLLTQQDETIDNPVLTSSYDSYFIKQRLKIQNDLLDSSKENLTPLKKKLLDPMFQYKDVLCEYTNYENDEKEYRELYSLHVLNHIYKTRDKILKDNQRLQENDDLECLDQGFTRPKVLIVVPTRDTAYQVVETIIEKSGLDQIDKKGKFKDQFFDDSLPPTSKPKSFRHVFKGNTNDFFVLGMKFTRKAIKLYSNFYQSDIIICSPLGIQMILENTDKKKRQDDFLSSIEVMIVDQLHSIEYQNISHVYTILEHINKIPQQQREADFSRIRMWYINDQAKFLRQTMLFTRYISPTANAIINGKCHNMAGRWKNNQIISSEDSSIGQLGIKIKQIFQRFDLVGGTVVDESDYRFKYFTSVVMQNIVKSTGYEDGILVYIPEYTDYMRLRNYMKEKTTILFSEINEYSTQKQLDSNRSMFQQGRTKVLLYTERLHHYRRYELKGIKSVIFYKPPTNPEFYNEVIRFTAKNAFLGKSDINISTIRTVYSKLDGLALQRIVGSKRAAILCHGQNESYDFK
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FKB1B_ASPFU
Sequence: MGLEKQTLRMGNGKDHPQPGDPVELNYTGYLYDESNPDHHKGKEFDSSKRRGPLKATIGAGDVIRGWDEGVRQMSLGEKAILTMSGEYAYGEKGFPGLIPPNASLVFEVELLKIKDHGLD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1B, FKBP, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
Protein: CP270_MOUSE
Sequence: MALFIFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKSMGMLAKKYGPVFTVYLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGIVFSNGETWKQTRRFSLMVLRSMGMGKKTIEDRIQEEILYMLDALRKTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQTFQDFMENFHRKIEILASPWSQLCSAYPILYYLPGIHNRFLKDVTQQKKFILEEINRHQKSLDLSNPQDFIDYFLIKMEKEKHNQKSEFTMDNLVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRRPTMQDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKKSDYFVAFSAGRRACIGEGLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVPPPFELCFIPV
What is the function of this protein?
A cytochrome P450 monooxygenase involved in muricholic acid (MCA) synthesis (PubMed:27638959).  Hydroxylates at the 6-beta position two major bile acids, chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) to form alpha-MCA and beta-MCA, respectively (PubMed:27638959).  May regulate NR1H4/farnesoid X receptor signaling, as taurine-conjugated MCAs are antagonists of NR1H4.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:27638959).
What are the official names of this protein?
Cytochrome P450 2C70, CYPIIC70.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: FAA10_MYCTU
Sequence: MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the phosphopantetheine arm of the acyl carrier protein (ACP) Rv0100 (PubMed:22451903, PubMed:23625916).  Can use octanoate (C8), decanoate (C10), dodecanoate (C12), tetradecanoate (C14) and hexadecanoate (C16), but not hexanoate (C6) (PubMed:22451903, PubMed:23625916).  Long chain saturated fatty acids are the preferred substrates (PubMed:23625916).  Cannot use coenzyme A to form acyl-CoA (PubMed:22451903, PubMed:23625916).
What are the official names of this protein?
Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase FadD10, FAAL10.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_KORVE
Sequence: MIIKEAKDAKRGRVHSRIRKKMEGTPERPRLNVYRSTNHLYVQVIDDSKGATLVAANTLEFGEAKEGKRPTGGNLSAAKQLGKAIAERAKQKGINKVVFDRGGYLYHGRIKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: WHIA_MYCPN
Sequence: MSFSVQIKHELATNPLIKTEWSSFLAGYFQNGLKLLATGQWSFKTSTATLKALFSNALQFSFQIHETSTHCEFSFRASQTEVDQLLAFDATQSDLPLQKAYVIGAFLSGGSVSDLLHSSNFHLQISTNNELQIKQLMKLFHPFKQTTKRHQLLVYVKSYQAICDFFKLVEAFDGYLAFEENQLQKNFALEQVRKSNLEIANLMRTLKTSTSTAEQLKILINSADFKKQSLNFQRFCLVKLDHPDWSLEQIAQFFERKYKVQITRSGIQHLNAKLKKLNQN
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: FLGJ_VIBPA
Sequence: MMKNPNDIGFIHDISSLDSLRQKAVKEGKDGEQEALHAAARQFESIFTSMMLKSMREANEGFESNIMNSQNEKFYRQMLDEQMASELSANGSMGLADMIVAQLTAGQGNDKSETAMRDAANSAVEYRRVDPKKAREIEKRLIESGELSRTSHTPAKFDSPESFVNSMKPYAEKAAKALGVEPSLLLAQAALETGWGQKVVQNARGSSNNLFNIKADRSWQGDKVTTQTLEFHDNTPVKETAAFRSYSNYQDSFNDYVRFLNDNPRYETALQQRGDSESFIRGIHRAGYATDPTYADKVLQVKQKIESM
What is the function of this protein?
Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
What are the official names of this protein?
Peptidoglycan hydrolase FlgJ, Muramidase FlgJ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPFD_MYCSK
Sequence: MSTFIGQLIGFAVIVFLLVRFVVPPVRRMMTAQQETVRRQLEESSTAANKVAQADQQHAKAVEEAKADARRVVDEARSDAEKIAEQMRAQADAEVERIKVQGQAQVQLLRQQLIRELRSHLGTESVARARELVRDHVSDDDNRSATVDRFLDELDAMAPSDAALDDAVGSRMRSTSRESLKALVSRFDELTADVDADGLTSLGDELAAVAKLLKTEPVLGKHFGEPTEDGEGKANLAEAVLSGKISDTALEVVKAAVAQRWSDESDLDYAVRHTARLALLVRAERNDETSEVEDQLFRFSRILDSESRLSGVLSDYTTPVDGRIGLLDRLLGDQAGETTRALLAQTVELLRGERADEAVRELAELAVARRGEVVAHVNAAAELSDAQRTRLAEVLGRIYGRPASLQLHIDPDMLGGLTIAVGDEVIDGSLASRLASAETQLPD
What is the function of this protein?
This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta).  Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0) (By similarity).
What are the official names of this protein?
ATP synthase subunit b-delta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.