PharMolix/UniProtQA huggingface dataset:
Protein: NADK_HYPNA
Sequence: MTPLRIAFYASKRPEAQQVLPQLRDKYGHYSEEEADVIVALGGDGAMLDTLRRRFDDGKPVYGMHLGTVGFLMNDFHADGLPERIEAAERATLSPLRMQATDLDGTVHRAMAINEISLLRQTAQSARLKIIVDGRVRMEELVCDGLMVATPAGSTAYNLSAHGPILPIGAKLLALTPVSAFRPRRWRGALLKAEARVDIEVVAPDRRPVSASADNEEVRNIAKVTVETDPARTLKVLFDPGHALDERILREQFAF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IREB2_MOUSE
Sequence: MDSPSAGYTFEYLIETLNGNSQKKFFNVPKLGGTKYDILPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQSKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSGAFKNVAVIPPGTGMAHQVNLEYLSRVVFEETDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSIDIVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTGFDKTKLESMEKYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEIGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFDIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGVLSGNKHFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKEIYLHDIWPSREEVHQMEEEHVILSMFKTLKEKVEMGNKRWNSLEAPDSVLFPWDVKSTYIRCPSFFDKLTKEPAASQPIENAHVLLYLGDSVTTDHISPAGSIARSSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLEFLPGENADSLGLSGREVFSLSFPEELFPGITLNIKTSTGKEFSVIASFANDVEITLYKHGGLLNFVARKFL
What is the function of this protein?
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA.  Binding to the IRE element in ferritin results in the repression of its mRNA translation.  Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
What are the official names of this protein?
Iron-responsive element-binding protein 2, IRE-BP 2, Iron regulatory protein 2, IRP2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_XYLF2
Sequence: MSMTAQKALQRIVEHREILQDEMVQLMRQIMNSEVSGIMVAAILAGLRVKKETVGEIAGAATVMREFSRKVNVQDRTHLVDIVGTGGDGWHTFNISTCAMFVAAAAGAKVAKHGNRSVSSKSGSADVLEALGASIELQPLEVAEAIGCIGVGFMFAPIHHPVMQVVSPVRREMGVRTIFNILGPLTNPADAPNILMGVFDPDLVGIQVHVLHKLGAERALVVCGRDGMDELSLGTTTLVGELRGGRVCEYEVSPEDYGMAVSPISNLRVESSAESREMLLNVLAGKPGPALDVVALNAGAALYVAGVAQDIGHGVALAREVIFNGRARNILNQYVAFTRRPRNV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SYR_MYCCT
Sequence: MNRTIIEMFYDDLKNICQKFNITKEPIIEINKNNTPGLLSSSICLISSKQVNKKPLDLANDFKEQLLLTNNYSSIQIANPGFLNVLVKPEILSNVISNVLTLKSKYGNLEKQNKIINIEYVSANPTGYLHVGHARNAVIGSVLVNLFKKAGYKVQTEYYVNDAGNQINVLAVTVFVHYLQALNIDAKKPENCYAGEMYDDLAKIIINKYNDQFKDIKYTDNKILDDNVHSLFKQISIDYFLKIIKQQLADFNVKIRHWSSEQEVYDTHQIEKVLKLYKSKDASYYKDGAEFLKTTQFGDDKDRVLVKSDKTYTYILPDLATHHLRIKRTKADKLINVWGGDHHGYIKRMQAGLALLGNDPDILEIQMVQMVRLIKDGSEYKMSKRKGTAVWLVDILELVGVDALRYMLASKSSNSHMDLDLDLITLKNSSNPIYYAQYATARCHSILNQAKIKKITPLVKETNLLNNPKEIELLLILDNFKEVIKNSANNRSTQQICDYIQNICKIFHSYYAEIKIIDENNLELTKLRLGFIKAILQVLKNAFFIIGIQPVVEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAA_SHIF8
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGESIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_ECOLI
Sequence: MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIPSSGDLSESDDWSEEPKQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RNP3_METM6
Sequence: MLEGIIDINHIFDEEGIKTLKRFGWDGSVAVQNHNEYSEEIINSTVEYGEKHDFKVFSGVKISTKNQNEMEKAIKKYRNKVDILLVEGGDIKINRRVLEMNDVDILSTPELNRMDNGLDHILARLGSTNRVAIELNFGNLLKSRNYDRSKILWAFQRNLKLAKKYDTPVVISSGASDIYGIKAPGDLRGFLNTITDPLYSKKIMETTSKIIDYRLYLKKDTVLTLGIEIVEE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y017_HVAVE
Sequence: MVATGRIIITLLAAALDEIILASKITQEAYDSDFSSPRYALTGSLAESVYGKQCYGDCVNYTCVVSRTGSLDPCLYTTKSIRIVHPAAKVLQKRETFCRSACITDDTVPWCIIDRYGTVDLCEPIKPNRKQPSLAVELSVDGKHPTGRTTTCSTRCKYRPSNEGSIGHRCVVRNGMNYAEWACSPNPVIMPPAIPTYNNAGSLDGLTECNLKTGLRIGLTIGDNEYSDSTNVSSGIAVLDYDGAVISIMTAYKQYITYVDAKEKPLTTLGILNTADDVGTKMVVYAMARVTAESVESLHKSLLNVLGDYSLPNGFGRFQRGLSGWLIGGHKYRNIEIKMLIHRRENNTEVEAISVDLKFRHGRYRLMNSCKGLIIL
What are the official names of this protein?
Uncharacterized protein ORF17.
What is the protein family that this protein belongs to?
Belongs to the ascovirus HvAV ORF17 family.
Protein: ALR_LACGA
Sequence: MVPGIHRPAVVKVNLGAIKRNIENEMQHLEPGQKMLAVVKANGYGHGAVEVAKVADQIGAAGFCVAILDEALELRRADITKTILVLGVVSPEYAPIAAANDISLTVPNLEWLKEAEKYLENSDLQLKIHLGIDSGMGRIGFNEDKDFIAANKFLENNDNFYIEGMFAHFASADSSDETYFKHQCEKFNHMKSLLTVKPKWIHVDNTAASIFHNGIKSDLVRFGIGIYGLNPSSNPNSPDLKSKIALDPALSFESELTHVKTIHQGDGVGYGSTFVADKDTIIGTVPVGYADGFIRKFQGFKVKVGNTYCPIVGRICMDQFMVEMPKEMPLGTKVVIISDNPDDLNNIKAAADYVDTIHYEVACLLNDRLPRVYYED
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PGLR_MALDO
Sequence: MALKTQLLWSFVVVFVVSFSTTSCSGSSFQEVNALHSYVDHVDDKESGYNSRAYPSYTDTIEGLKVMELIRPRTQLFSSRKLNTITGGIATSSAPAKTISVDDFGAKGNGADDTQAFVKAWKAACSSSGAMVLVVPQKNYLVRPIEFSGPCKSQLTLQIYGTIEASEDRSIYKDIDHWLIFDNVQNLLVVGPGTINGNGNIWWKNSCKIKPQPPCGTYAPTAVTFNRCNNLVVKNLNIQDAQQIHVIFQNCINVQASCLTVTAPEDSPNTDGIHVTNTQNITISSSVIGTGDDCISIVSGSQRVQATDITCGPGHGISIGSLGEDGSEDHVSGVFVNGAKLSGTSNGLRIKTWKGGSGSATNIVFQNVQMNDVTNPIIIDQNYCDHKTKDCKQQKSAVQVKNVLYQNIRGTSASGDAITLNCSQSVPCQGIVLQSVQLQNGRAECNNVQPAYKGVVSPRC
What is the function of this protein?
Acts in concert with the pectinesterase, in the ripening process.  Is involved in cell wall metabolism, specifically in polyuronide degradation.
What are the official names of this protein?
Polygalacturonase, PG, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: RIBL_ARCPA
Sequence: MVRVVATGTFDIIHPGHIRFLEEAKKLGDELIVIVAREKNVRHKPKPIIPEEQRVRVVSALKPVDKAILGDEHDIFKPIMELKPDIIALGYDQHFDEKKLEEELRKRGLNTRVVRIKAKEECEYCSSTKIIKRIVDVVKSRLQEYEEFFRSRGML
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: DNLJ_SHEB5
Sequence: MKEFKFNDEQLSTIQELEVDIDLKKLEIAISKESIDELSEDELLALLKVTNALYRSGFPVIEDILYDSFWNKFALNHPNHPFITSVETEVLNLGKTVALPQKMLSTDKAYSKEEIKKWLDRILKAAEELDIDTNEIEIRITPKLDGYAAFDDGERLYTRGDGVKGQDVSRAFERGLKVVRNSERGLGAGEIVINKAYFEKKLSQYFENSRNIQAAIIAEKNVDERVLEAIKEGACVFHPFAVLPNWTGNYQDLMTDFDGIIEQVWNSVEYDVDGVILEATDTRIKEHMGANRKFHRWQIAFKINDEVAEVEVISVTPQTSRTGRVTPVAELVPTRISGAMISRVTVHHYNMVKINGVGPGAIVQIVRSGLVIPKIEKVIKPVDPQMPELCPSCKSHLLWESDHLVCPNKSDCPAQTENTLVHFFKTLANNDGFGPKNIEKLANLGVKHIHQMYDLKPHQFAMYGFGEKTSKNLYDQLQASKNIEIEDWRFLSAFGVSRLGGGNCEKLLQHYSLRELFEATVEDIAELNGFARVSAEAIVKGLANIKEEFFKVYDLGFNLSITPKQSELESLASPLTGKIVVFTGKMLQGKRSDMEKHAKALGAKVGTSVTSNTTYLIAGLKVGETKINDAKEKGVKVLSEQEYLDLIS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: KN8A_ARATH
Sequence: MPVSTRSKVMKQERNEQENTNLNLPLRNPHQGLKEKMRALTLLYEQQKRASFSLRNPNHNQSPKPEDQRFKTQLLDSSKKGDRFHRLDGKDSTFVEEDTKENNVFEADRIFGVSSVPVKPSGVIRKLSMGNGARNVSEAEKLESLNASVSRILVFVRLRPMGKKERENGSRCCVKVLNKRDVYLTEFTNENDYLRLKRLRVRHFTFDSSFPETTTQQEVYSTTTGDLVEAVLEGRNGSVFCYGATGAGKTYTMLGTMENPGVMVLAIKDLFAKVRQRSLDGNHVVHLSYLEVYNETVRDLLSPGRPLILREDKQGIVAAGLTQYRAYSTDEVMALLQRGNQNRTTEPTRCNETSSRSHAILQVIVEYKTRDASMNIISRVGKLSLIDLAGSERALATDQRTLRSLEGANINRSLLALSSCINALVEGKKHIPYRNSKLTQLLKDSLGGSCNTVMIANISPSSQSFGETQNTLHWADRAKEIRVKECEVNEEVVQVGEEEGADQAKLLLELQKENSELRVQLAKQQQKLLTLQAENIAAANNNNNISLTPPSISSLMTPPSALTAQQKKKPRHSLLSGTCFTPESLKRTKAEEAVKELQLTVKALKMEMERMKREHGLQMKKQKDELMKDLCSRKSEKTPERCKETRRIVTRGSLRPKEKEKELKSPSHRFASPVAAAKKRSFWDITVANTSPALDRRKTRSHGLVHQEAPSKLLQPGFARPHMKH
What are the official names of this protein?
Kinesin-like protein KIN-8A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-8 subfamily.
Protein: ATPB_CHLRE
Sequence: MSDSIETKNMGRIVQIIGPVLDIVFAKGQVPNIYNALTIRAKNSAGTEMAVTCEVQQLLGDNCVRAVSMNPTEGLMRGMEVVDTGKPLSVPVGKVTLGRIFNVLGEPVDNMGNVKVEETLPIHRTAPAFVDLDTRLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFAGVGERTREGNDLYTEMKESGVIVEKNLSDSKVALVYGQMNEPPGARMRVALTALTMAEYFRDVNKQDVLFFIDNIFRFVQAGAEVSALLGRMPSAVGYQPTLATEMGGLQERITSTKDGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRNLAAKGIYPAVDPLESTSTMLQPWILGEKHYDSAQSVKKTLQRYKELQDIIAILGLDELSEEDRLIVARARKIERFLSQPFFVAEVFTGSPGKYVSLAETIEGFGKIFAGELDDLPEQAFYLVGNITEAISKAASLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HTM_MYCA9
Sequence: MTENLQDMFESSYRGEAPEQLAARPPWSIGQPQPEILKLIEQGKVHGDVLDAGCGEAATALYLAERGHTAVGLDAAPTAIQLAKGYAAERGLTNVTFDVADISNFTGYDGRFGTIIDSTLFHSMPVELREGYQQSIVRAAAPGANYIVLVFDKAAFPPDIDGPHPVSEPELREIVSKYWTVDDISPARLYANGDGFQDGGAQRFAEFREESNGWVSMAGWLLQAHRD
What is the function of this protein?
Involved in cellular response to chemical stress and may contribute to resistance toward antimicrobial natural compounds as well as drugs (Probable).  Catalyzes the methylation and detoxification of the P. aeruginosa toxin 2-heptyl-1-hydroxy-4(1H)-quinolinone (HQNO) to 2-heptyl-1-methoxy-4(1H)-quinolinone (HMOQ) (PubMed:33064871).  Can also methylate 3-bromo-2-heptyl-1-hydroxy-4(1H)-quinolinone, and shows much lower activity with 1-hydroxyquinolin-4(1H)-one, quercetin, 4-hydroxyquinolin-2(1H)-one (DHQ) and 4-hydroxyisoquinolin-1(2H)-one (PubMed:33064871).
What are the official names of this protein?
2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase, HQNO methyltransferase, HQNO-MTase, Heterocyclic toxin methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THG1_SCHPO
Sequence: MAKSRFEYVKQYERLDRLLPETYIVIRIDGKGFHKFTKKHDFEKPNDLRCLNLMNAAARVVMSEFTDIVLAYGDSDEYSFVWSKSTELYERRESKLVSHVCSLFTSAFVFNWPKHFDIPLLSLPSFDGRAVLYPNMKVLRDYLHWRQVDCHINNLYNTTFWMLILKGGFTNTQAEEYLKGTVSAEKHEILFSKFGINYNFEPEIYKKGSIWIREPIDQEWHQQDKKFSVKQKKKMVLSILHVSLIDDDFWTSRPFLEVLLQ
What is the function of this protein?
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
What are the official names of this protein?
tRNA(His) guanylyltransferase, tRNA-histidine guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(His) guanylyltransferase family.
Protein: ENGB_CAMJJ
Sequence: MIIGAKFITSLVKFDENLSSNFSEVAFLGRSNVGKSSLINSLCKQKNLAKSSATPGKTQLINFFEVTCKRNEEKFNINFIDLPGFGYAKVSKNLKEIWNQNLDEFLKLRTSIKLFIHLIDSRHTHLEIDVNLNDYLKRFLRPDQKILKVFTKCDKLNQSEKAKLKNEFKDSILVSNLNKFGLDSLEDIIINQTLGLDK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TATA_GLOVI
Sequence: MPFGLGLPEILVIGVIALLIFGPKKLPEMGSALGKAIRGFKSGVSDEPAPQQSASKETAPNPPQSLPSGKDS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ATPD_PSEAB
Sequence: MAELTTLARPYAKAAFEYAQAHQQLADWSAALGVLAAVSQDDTVRQLLKEPQLTSSAKAQSLIDVCGDKLNAPAQNFVRTVAENKRLELLPTIAEMYEQLKAEQEKSVEVEVTSAFTLSKEQQDKLAKALSARLSREVRLHASEDASLIGGVIIRAGDLVIDGSVRGKLAKLAEALKS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C93B2_GERHY
Sequence: MNTLQLIFLLFFFPTLLFLYCLPYKRNQNHRRLPPSPPSFPIIGHLHHLGPLIHQSFHALSTRYGSLIHLRLGSVPCVVVSTPDLAKDFLKTNELAFSSRKHSLAIDHITYGVAFAFAPYGTYWKFIKKLFTVELLGTQNLSHFLPIRTHEIRELLRTLMVKSRAKERVNLTEELLKLTNNVISQMMMSIRCSGTNSEADEAKNLVREVTKIFGQFNVSDFIWFCKNIDLQGFKKRYEGTHRRYDALLERIIMGREENRRRGKIKDGEGKDFLDMLLDVLEDGKAEIKITRDHIKALILDFLTAGTDTTAIAIEWALVELINNPNALEKARQEIDQVIGDERLVQESDTPNLPYIQAIIKEALRLHPPIPMLIRKSTENVIVQGYDIPAGTLLFVNIWSIGRNPQCWETPLEFKPHRFLDGGDLKSSLDIKGHNFQLLPFGTGRRGCPGVNLAMRELSVVIANLIQCFDWDVVGERLLNTDERAGLTAPRAVDFVCVPLERGNTLKILGSN
What is the function of this protein?
Functions as flavone synthase II (FNSII) that catalyzes the direct conversion of flavanones to flavones (PubMed:10652133).  In vitro, can convert liquiritigenin, naringenin and eriodictyol to 7,4'-dihydroxyflavone, apigenin and luteolin, respectively (PubMed:10652133).
What are the official names of this protein?
Cytochrome P450 93B2, Flavone synthase II, FNSII.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AROA_ALIFM
Sequence: MESLTLQPISKIDGQINLPGSKSVSNRALLLAALASGTTKLTNLLDSDDIRHMLNALKALGVEYKLSADKTECEVTGLGRAFEPNEALELFLGNAGTAMRPLAAALCLGQGEFVLTGEPRMKERPIGHLVTALKAAGADVEYLENENYPPLKIKGTGLHGGTVEIDGSISSQFLTAFLMAAPLSTQETTIKIVGDLVSKPYIDITLDIMATFGVKIENQNYQTFVVPANQTYVAPGDFLVEGDASSASYFLAAAAIKGGEVKVTGIGKKSIQGDVQFADALAAMGTEIEWGDDYVIARKGELNAIDMDFNHIPDAAMTIATAALFAKGTTSIRNVYNWRVKETDRLAAMATELRKVGAVVEEGEDYITITPPASLQHASIDTYDDHRMAMCFSLVALSDTPVTINDPGCTSKTFPDYFDKLKELSC
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E4PD_SHIF8
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_STRP1
Sequence: MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYIATGKNNPVKLEEVVSGVAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVGVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLKDVLLEPTRIYVKAALPLIKEELVKGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVLPIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKADASVVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOR4A_DANRE
Sequence: MGEQDPSDRLRGDQLKEPNQNGKGSFSQFSSSVRAMVRIRMKYQAIKKRRMEIASATPQIFTSPRSTSPKVFTFDNLHEPVNSNPASPRKRKKKRKGRVLYPTSSLRAVPTKESSRAKNCLYLLCIIVFLQVYNAIENLDDHVLKYDLEGLEKTLKREVFGQQEVAEGLLGHLQDYLSTYVHNKPLVLSFHGPTGVGKSHVGRLLAQHFRSVVGEELVMQYFVLHHCPTDDDIPVCTKSLESHISEMVSQGEEEEKIPVFIFDEVEHMPRQLMDTLRELIQPQNSNKYLNAIYILISNLGHEDITKFVLHNSSIAISGRLSLTQELTPWLRNYLQEHHGLFLDAEYLPFMLLEKSHVMDCFIDEMSREGFYPDRSHVERLAEELSYYIVGEREFSHTGCRQVVAKVNLL
What are the official names of this protein?
Torsin-4A, Torsin family 4 member A.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRDA_LACDA
Sequence: MVNTHVNLPGLDLKNPVMPASGTFGFGDVPAAQKFDLNDLGAMVIKTTTPHATTGNPQPQIAILEDGVLNSVGLTNPGVDQVISEKLTKLRHQYLDLPIMASVGGDSEDDYVEVAKKLSASGLVNALEINVSCPNVAQGGMSFGVHAGVVEELTKKIKMAVALPIYVKLTPNVTDIVEIAKAAESGGADGISMINTVLGMRIDVKTRKPLLGHNMGGLSGEAVKPIAIRMISQVRQVTQLPIIGMGGISTAQDVIEFILAGANAVAVGSAHFEDELAAKHIAENLPAELEKLGIEDINDLVGQVKFN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM59_MACFA
Sequence: MAAPKESLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYACQRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHLLFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQESTNLRESSLSKMSYLQMRNSQAHRNFLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSICGDLEFMNEQKLNKYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI
What is the function of this protein?
Acts as a regulator of autophagy in response to S. aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C).  Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy.  Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP.  Inhibits APP transport to the cell surface and further shedding.
What are the official names of this protein?
Transmembrane protein 59.
What is the protein family that this protein belongs to?
Belongs to the TMEM59 family.
What are the subcellular locations of this protein?
Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Mainly localizes to late endosomes/lysosomes. Probably first exported to the cell surface and then actively endocytosed to transiently localize in early endosomes on its way to the late endosomal/lysosomal compartment where it becomes quickly degraded.
Protein: APAH_YERPS
Sequence: MSTYLIGDIHGCLDELLALLAQVNFDPQQDTLWLTGDLVARGPASLDVLRYVRSLGPAVRMVLGNHDLHLLAVYAGISRNKPKDRITPLLDAPDADELINWLRRQPVLQVDDQLKLIMAHAGITPQWDIETAKMCAREVEAVLSSDSYPLFLDAMYGDMPNNWSPELTGLARLRFSTNALTRMRFCFPNGQLDMICKDTPENAPAPLKPWFDLPRLVDPEYSIIFGHWASLEGKGVPEGIYGLDTGCCWGGDLTLLRWEDKRYFTQRAFKAEAEINNNNGFAAGEEVQH
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y2012_DICDI
Sequence: METIQSVITEWSDSKSWDHLFQHNFKDSNWSELFDPVNFKFKFGTTPFSQFQILPSVISLYLVIIFSIKFLMRNRKPFSLKYVSILHNAILCIWSLVMCVGILYEVIKRITAEGPLFTVCETVSGFDKGPAYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCIVVWLCWYFMYSGWNLQLWVVFLNTFVHVFMYYFYFQTGRGKTVWWKKYITMIQIIQFICLGIAGLLHSAAINLNSSPCFTHYPAFISAYLINFSFLFLFSQFFVKSYSNKPTSSSSTTTPTKTKKID
What is the function of this protein?
Could be implicated in synthesis of very long chain fatty acids.
What are the official names of this protein?
Putative elongation of fatty acids protein DDB_G0272012, 3-keto acyl-CoA synthase DDB_G0272012, Very-long-chain 3-oxoacyl-CoA synthase DDB_G0272012.
What is the protein family that this protein belongs to?
Belongs to the ELO family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.