PharMolix/UniProtQA huggingface dataset:
Protein: KAP0_RAT
Sequence: MASGSMAASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEARQIQSLQKSGIRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
What are the official names of this protein?
cAMP-dependent protein kinase type I-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: METK_BDEBA
Sequence: MKNYLFTSESVSEGHPDKMADQISDGILDAILAQDPKGRVACETLLTTGLVVVAGEITTSAKVNFSEVARDVVKRIGYDHSDKGFDYKTCGVMIAVGQQSPDIAVGVKETLSDNQGAGDQGLMFGYAVNETPELMPLSIAMSHKLVKDLAALRKANKVDWLRPDAKSQVTVQYENGIAKRIDAVVISTQHADSVSNSTIQEFITEELIKKSIPGNWIDSKTKFFINPTGRFVTGGPMGDAGLTGRKIIVDTYGGHGAHGGGAFSGKDPSKVDRSAAYASRHIAKNIVGAGLAERCLVQVAYAIGVAEPVSITVNDYGTSKVGPEVLEKAVRQVFDLRPARITKDLDLLRPIYSPTAAYGHFGRNEESFTWERLNKVDQLKDAVKTLA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_PSEPW
Sequence: MALKSPAFRRKFPLLVTGGLLALQPFATSYVVAAEQFDCQVSASGGWDCKPKSPVNNLPPRPVHDGAALTSGTEAPSAEAESADKPVLVTESKGRGLKSRSEDYSHLDWVPREKLTAAQLAETGPYCGGAYIEPTRPGMADTTPKDESPTYINAKVSKYQQEQQIATLAGDVVMRQGSMQAEADEANLYQAENRGELKGNVRIRDNGSLVVGDEAQIQLDTGEAQVDNAEYVMHKSHIRGNALYAKRSENAIIRLKDGTYTTCEPGSNAWQLKGNNITLNPATGFGTATNVTLRVKDFPVFYTPYIYFPIDDRRQSGFLPPSFSSTSDTGFMLVTPYYFNLAPNYDATLYPRYMTKRGLLMEGEFRYLTKSSEGQLGGAYLNDKNDDRKEQTDYEDQRWMINWQHKGGLDERLMTEVDYTDISDPFYFQDLESDQIGVESNDVVNQQGALTWRGDTYTARLNAQAYEMATLSQITPYNKLPQITVDGMLPYHPGGFDFSYQTEAVRFDRDLKDDFVTDEDGNPDFTAGAAGRRLDENVSGIARANGNRLNFAPAISLPMQASYGYVTPKLKYVYTNYDLDLDGQGKQEALAQASQPGYGSYSSSISRDVPVFSVDSGLYFDRNTSMFGTNYRQTLEPRMFYLYVPYKDQTDIPLFDTSETLFNFDSLFRDNRFSGTDRIGDENKLSLGVTTRWIQDDGFERQNFSIGQALYFKDRKAQLPGINYRDRSDAQSDVSPYALVYNYYFNRDWRFNSDFNWDPDSRSTRSGSAMFHYQPEDNPNKVVNLGYRYRNDTIAYDSTTGTWKVGGGDYGNPGDPNYIKDYYKIQQHDFSVIWPIVPQWNVIARWQHDYNRNRTLEAMGGFEYDNCCWKLRLINRYWIDYDDFSQAAPQNEKGDHGIFLQIVLKGLGGVVGNKVESFLDQGIEGYREREDQAY
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ATPD_SALTY
Sequence: MSEFVTVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENNRLNALPDVLEQFIHLRAASEATSEVEVTSATALSEEQLSKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EIF3K_DROPE
Sequence: MSHLVKMENGQSQTIQEMLGCIERYNPDHLKTLEAYIQDQAKNNTYDLEANLAVLKLYQFNPHMLNFEITYTILLKSLTNLPHTDFVMAKCLLLPQQMKDENIQTIIDLADILERADFTLFWQRAEVNRTMFRHISGFHDSIRKFVSHVVSITFQTIKKDLLKELLGGIEDSTLESWIKRNGWKHQGQDLIVVAMQDDKIKTKNITEKIEFENVGALMAQCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_ECOK1
Sequence: MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALVWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRFPLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERLCGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFCN_SALSV
Sequence: MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPTRRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWQPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: RHG01_HUMAN
Sequence: MDPLSELQDDLTLDDTSEALNQLKLASIDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAPKPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL
What is the function of this protein?
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state.  Cdc42 seems to be the preferred substrate.
What are the official names of this protein?
Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_PROM1
Sequence: MAAINKTKGSADRIKMKIRKGDTVQVISGKDKGKTGEVLKTLPYENRVLVQGINQRTKHVKPSQEGETGRIETKEFPLHASNVMIYSTKEKVASKVEIFVDKDGSKKRRLKKTGELID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: THIC_GLUOX
Sequence: MNASIPAITTGPLPASSKVHVQGTLHDIKVPMRQIEISDECPLNVYDSSGPYTDTAISIDIAKGLADSRGIWLRSRGDVEEYDGRTITAVDNGFAEGERLTPAFPNQRRPLRAVGDRAVTQMAYARAGIITPEMEFVAIRENIGRTQALKEERDGEDFGASIPDFVTPEFVRQEIASGRAIIPANINHRELEPMIIGRNFLVKINANIGNSAVTSSMEEEVEKMVWSIRWGADTVMDLSTGRNIHNIRDWIIRNAPVPIGTVPLYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLHMIPLTARRVTGIVSRGGSIMAKWCLHHHRESFLYEHFEEICDICRRYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTKIAWAKDCQVMIEGPGHVPMHKIKTNMDKQLEHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKTGVITYKLAAHAADLAKGHPGAQMRDDALSRARFEFRWEDQFNLGLDPDTARAMHDETLPKQAHKVSHFCSMCGPKFCSMKISHDIRAAAEKQDGMEQMAEKFREGGQLYVPVTEPAE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RPOD_CAUVC
Sequence: MSNNSSAETEAPETTGGDGPLLDLTDAGVKKFIKQAKARGYVTMDELNKVLPSEEVSPDAIEDTLAMLSEMGVNVVEAEEDAENAEGGEVATRDENTTVIASDKPAAYDRTDDPVRMYLREMGSVELLSREGEIAIAKRIEAGRDTMIRGLCESALTFEAIMVWREELGTGRILLREVIDLEGTYAAINGVAAQPAAEDDEGPAEPVDDEAGEAKAEGAEGEDEDDFDDGAGPTVSAMEGELREGVMAILDAIASEFEAFRKLQDKLVGSRLKGEDLSDADRKAYEGLSATIIQHLKTLKLNNNRIEALVEQLYAINKRLIGLEGRLLRLADSYGISRGEFLKAYFGSELNPTWSEQVKAMGVRWTKFVENDSQSVTDIRSEIAALATETGVPIDDYRRIVQTVQKGEREARQAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKIVRTSRQMLHEIGREPTPEELAEKLAMPLEKVRKVLKIAKEPISLETPIGDEEDSHLGDFIEDKNAILPIDAAIQSNLRETTTRVLASLTPREERVLRMRFGIGMNTDHTLEEVGQQFSVTRERIRQIEAKALRKLKHPSRSRKLRSFLDS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-70.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL112_CAEEL
Sequence: MGDIEKQTEIREKKARNVMRELKIQKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRTFGIRRNEKIAVHCTVRGPKAEEILEKGLKVKEYELYKENFSDTGNFGFGVQEHIDLGIKYDPSIGIYGMDFYVVLDRAGRRIAKRRRAPGRVGPSHRVEREESIKWFQQKYDGIILPPKPKVKRTFHRRR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11-2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HDFR_ECOL5
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDVHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFCSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ASPX_PAPHA
Sequence: MNMFLLLMSLYLLGSARGTSGQSDESSGSIDHQTSVQQLSGEFFSLENPSDAEALYETASGLNTLSEHGSSEHGSREHTVAEHTPGEHAESEHASGEPAATGHAEGEHTVGEQPSGEQPSGEHLSGEQSLGEHASGEQPSDEQLSGEHASGEQPSGEHASGEQPSGEQPSGEHASGEQSLGEHALSEKPSGEQPSGAPISSISTGTILNCYTCAYMNDQGRCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
What are the official names of this protein?
Acrosomal protein SP-10, Acrosomal vesicle protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Nascent acrosomal vesicle of Golgi phase spermatids.
Protein: RL9_HERA2
Sequence: MKVLLIQDVEHLGTAGDIKEVSGGYGRNYLLPKKLAVFATPGLIKQAEERLAKQRKLEAKQREELRGLADSINGVTLKFVTKVGEQDRLYGSVTSSDIAEKLQAAIGQEVDRRKIQLDEPIKRTGVYSIGVRLLAGLEPHINVVVEGENGEGSVQPAAEAAEVASTEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RLMH_LYSSC
Sequence: MNITIVSVGKLKEKYLKMGIDEYVKRLGGYAKIDLIEVADEKAPEQLSDAEMEIVKKKEGERILAKISTDTYVIALAINGKMKTSEQMAADLESLMTYGKSKIAFVIGGSLGLHEDVLKRADEQQSFGKMTLPHQLMKLVLVEQVYRSFRIMKGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNS1_XENLA
Sequence: MTSRRSHGDVTPFLTQADNTEEEGVRDPESQSSDEEEEEGKDHGKETHLLTGISYKRSVIIVIILFYINLLNYMDRFTVAGVLPDIKKAFNISDSNSGLVQTVFICSYMFLAPVFGYLGDRYNRKLIMCVGISFWSLVTLLSSFVSNQYFWLFLITRGLVGVGEASYSTIAPTIIADLFLADQRTRMLSFFYFATPVGCGLGYIVGSEMTSAAGDWHWALRVTPGLGLLAVLLLIFVAEEPPRGALERKTDRPLTNTSWSSDMKALLKNPSFILSTFGFTTVAFVTGALALWGPTYLMRSRMVIYKSKPCEGGICNYDDSMIFGGITCITGILGVLTGVEISKRYRKTNPRADPLVCAVGMISSAPFLFLSLAFADTSLVATYVFIFIGETLLSLNWALVADILLYVVIPTRRSTAEALQIVVSHLLGDAGSPYLIGVISDQIQKGKPASFLIQMRSLEYALMICAFVGVIGGGFFLTTALFIEKDRKKAELFSQGLLPADETDAERIVVPKRGRSTKVPVSSVLI
What is the function of this protein?
Mediates the rate-limiting, proton-dependent, lysosomal efflux of lysophospholipids.  Selective for zwitterionic headgroups such as lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE) (By similarity).  Essential player in lysosomal homeostasis (By similarity).
What are the official names of this protein?
Protein spinster homolog 1, Spns1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: H7_FOWPN
Sequence: MDHKSRMLLDTIFKDMLNTKDVYALIKYIFKKDPVETIFSKKDDDIFIDFVYNDNVLASDYLGMKTTKVEDCCSCRKVVAVEYMNTSIIDNDLEGYIKQSDKLKRFIKLYNKNNAIKKARNIKSRQKMLKDAGIDDIGYEFIKDAIGLISRK
What is the function of this protein?
Contributes to the formation of crescents and immature virions (IV).
What are the official names of this protein?
Late protein H7 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae H7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Probably transitorily part of the membrane of crescents during immature virions formation. Not incorporated into virions. Probably synthesized, but not retained in viral factories (By similarity).
Protein: PVK2_MANRE
Sequence: GASGLIPFPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, Manre-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: S35B2_HUMAN
Sequence: MDARWWAVVVLAAFPSLGAGGETPEAPPESWTQLWFFRFVVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKACVFGNEPKASDEVPLAPRTEAAETTPMWQALKLLFCATGLQVSYLTWGVLQERVMTRSYGATATSPGERFTDSQFLVLMNRVLALIVAGLSCVLCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEPRSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGTRFMGRHSEFAAHALLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESPVQKV
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi.  May indirectly participate in activation of the NF-kappa-B and MAPK pathways.
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 1, PAPS transporter 1, Putative MAPK-activating protein PM15, Putative NF-kappa-B-activating protein 48, Solute carrier family 35 member B2.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RIR2_MYCGA
Sequence: MSNNNKYYDKSFSPLGYVANGQKGVMRSINWNVINDPKDLEVWTRVTQNFWLPEKIPVSNDLKSWNELTPEWKQLVTRTFTGLTLLDTIQCTLGDIAQIPNSLTDHEQFVYANFSFMVGVHARSYGTIFSTLNTSDEIEEAHEWVINNEKLQARAKFLVPYYTSDDPLKSKIAAALMPGFLLYGGFYLPFYLAARGKLPNTSDIIRLILRDKVIHNYYSGYKYRLKVQKLPKEKQEEYKKFVFEILYKLIELEKDFLRELYDGFGLADEAIAFSLYNAGKFLQNCGYESPFTPEETKISPEVFAQLSARADENHDFFSGNGSSYIMGVTEETQDDDWEF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: IXTPA_THEKO
Sequence: MRLAFVTSNPGKVEEARKYFEPLGVEVYQLKVSYPEIQADTLEEVAEYGAKWLAQRVDGPFFLDDSGLFVEALKGFPGVYSAYVYKTIGYQGILKLLQGEKNRKAHFKSVIAYWDGELHIFTGRVDGKIATEPRGSGGFGFDPIFIPEGFDRTFAEMTTEEKNRISHRGRALREFANWLKENLK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: AP2E_DANRE
Sequence: MLVHSYSSMERADGLSSSSPGGRLSQLNQAAYSSAPPLCHTPASDFQPPYFPPPYPQSSLSYSQSQDGGYPHLPEPYPSLNSLHQHQQAAWHSQRSRSEDAGLLSQPHRALSLDPRREYPGVPRLLTHGLGDGAAALGDGPLGMHAVHHGLDDIQGLEEASALGILDHSVIKKVPLPSKLNGSTISALSLSKEGLGLGGVSNPAEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLAPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTALVEGEAVHLARDFGYVCETEFPARATAEYLCRQTEPDQLPTRRSMLLATKEICKEFVDLMSQDRSPLGASRPTPCLEPGVQSSLTHFSLLTHGFGTPALCAALSAFQSYLLEALKLLDKGENGGKNHHDKELKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions.
What are the official names of this protein?
Transcription factor AP-2-epsilon, AP-2-epsilon.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AGLUS_THESQ
Sequence: MAKRKVPPEFVVERDDYKCIRCLACVRVCSYGANFYDENANRVYTENTKCVGCHFCEAICPTEAITVRKNDFDIRPLAHWTPEHLIGIMKQAETGGVLLTSMGNDRPYFSYFDRIVLNASQVTNPSIDPLREPMEIRTYIGRKEEKLEIEEDEDGTVKLKTEIAPQLKLEVPVMFTAMSYGSISLNAILSLARAARTVGTFFNTGEGGLPKELREFKDNMIVQVASGRFGVSADYLNAGSAVEIKIGQGAKPGIGGHLPGEKVTEPISETRMIPVGTDALSPAPHHDIYSIEDLRQLIYAIKEATRYEKPVGVKIAAVHNVAPIAAGAVRAGADYIVIDGIRGGTGAAPKITRDHVGIPIEFAVAVVDQRLREEGIRHMASIVVAGGIRNSADVIKAIALGADAVYIGTAALISLGCHLCQTCYLGKCNWGIATQDPKLTKRLNPEIGARRAANLLRAWAHEIKEILGGMGINAIESLRGNREVLRGVGLHEYELKLLGIKPAGEAW
What are the official names of this protein?
Archaeal-type glutamate synthase [NADPH], Archaeal-type NADPH-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
Protein: ST7_NEMVE
Sequence: MEHQGTGIFHLGAPFLLKVKQWVGWSWTYLWGFWFLLVIFLLYILRAPLRLKENMNLVILFLNTLTPKFYVALTGTSSFISGIILIFEWWYFRKYGTSFIEHISLAHLGPLIGGGDNTAPNSSQNVAECKVWRNPMNLFRGAEYSRYLWVTGREPLTYYDMNLSAQDHQTFFTCDADETSSNSADTIMLTAWRERDQEKRINAACRAYECDPTSPTALILLAEEKAQTITEAEWYLKQALKTSDDLIRNGASTNGDGKEDTIHRKNTNVCVYIRRRLAMCARKLGRTKEAIKMMRDLMKEFPLMSVLNIHENLIEALLEVQAYSEVQQVLAKYDDITLPKSATICYTAALLKARAVCDKFSPEVAAKRGLSPAEMAAVEAIHRAVEFNPHVPKYLLEQKSLILPPEHILKRGDSEAVAYAFYHLPHWKQVEGAINLLHCTWEGTFRLVPYPLEKGHLFHPYPGCTENADRELLPVHHQLSVYPKKELPFFILFTAGLCSFTALLALLTHQFPEPMAHLAKTSLGWISAPFSLLIQKVEDFFPAHILHQLTRI
What are the official names of this protein?
Protein ST7 homolog.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MMSA_CAEEL
Sequence: MLSRLARVQPKCQQLAHFSTSKSAAAAPTVKLWIDGQAVESKTTDFVELTNPATNEVIAMVPNATQAEMQAAVDSAKNAFNTWKNTSPLTRQQCMFKLQALIKRDMKKLAESITIEQGKTLPDAEGDVSRGLQVVEHACSVPSLMMGETLPNVSRDMDTHSYRIPLGVTAGICPFNFPAMIPLWMFPVALATGNTMVIKPSEQDPGAAQLLVELAKEAGVPDGCVNIIHGQHSAVNFICDNPDIKAISFVGGDAAGKHIYERGAKNGKRVQSNMGAKNHGVIMADANKEQTLNQLTAAAFGAAGQRCMALTTAVLVGEARAWLPELVEKAKNLKVNAGWKPDTDIGPLISKQSKARVLRLIESAKKEGAQVPLDGSNITVPGFENGNFVGPTILAGVKPNMTCYREEIFGPVLVVMEAENLNEAIEIINNNPYGNGTAIFTSNGATARKFTNEVDVGQIGINVPIPVPLPMFSFTGSRGSFLGDLNFYGKAGIQFYTQWKTVTQYWNESLTELKPQMSFPQLK
What is the function of this protein?
Plays a role in valine and pyrimidine metabolism.  Binds fatty acyl-CoA (By similarity).
What are the official names of this protein?
Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating].
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYFA_CERS4
Sequence: MTALDTLRGKYIEAISSAADEAALEEVRLAALGKKGEISLKMRELGQMSPEERQTTGAALNRLRDEIDASLRARKQGLADAALDARLKTEWLDVTLPGRPRRAGTIHPVSQVMAELTAIFADMGFAVAEGPQVESDWFNFDALNIPPEHPARQEHDTFFMARAEGDDRPPHVLRTHTSPVQIRAMQAQGAPIRVIAPGRVYRMDMDQTHTPMFHQVEGLAIDRDISMANLKWVLEEFCRAFFEVPSVELRFRASHFPFTEPSAEVDIRCSWEGGQLRIGEGDGWLEILGSGMVHPKVLAAAGVNPDEWQGFAFGMGIDRIAMLKYGIPDLRAFFESDLRWLRHYGFAALDMPDLAGGLSR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF2_MOUSE
Sequence: MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPVEIDMIVGKDREGFFTNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-2, Profilin II.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.