PharMolix/UniProtQA huggingface dataset:
Protein: Y298_MYCTU
Sequence: MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin Rv0299.
What are the official names of this protein?
Antitoxin Rv0298.
Protein: PDXT_STRPJ
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: TPIS_PSET1
Sequence: MAARKAMVAGNWKMNGSLELVKQMSDAINNVKSNEIDIVLFPPFPLVSAMIASGVSTGTQTVSENTPGAFTGEVDAQLIKELGAQYVLVGHSERRSIYKESNDVVAAKFARAQQVGLTPILCVGESESEQENGKTEQIVAAQIDAVIEKLGVAALKDSVIAYEPVWAIGTGKTASPEQAQSVHKFIRDKIASLNSDLAQGLTILYGGSVNEKNSELLFAQTDIDGGLIGGASLKADSFTAICNSAKGTV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SYNJA
Sequence: MDPKLEQRARELRALLQKASIAYYVHDAPILEDSVYDRLYRELQELERAYPELITPDSPTQRVGEKPAEQFPTVSHRIPLYSLENAFNLEELKEWQERLWRVLGRTPEEGELEYVCELKIDGAALALTYVDGLLQRGATRGDGQSGEDITPNIRAIPSIPLRLATAAPPPVLEVRGEAYLPIAEFERINRERCSAGDPPFANPRNCAAGTLRQLDSRVVAARKLSFFAYALHWPEGWPSGDPPQTQWECLQRLKDLGLPVNPLSQVCRGLEEVVQFYERWRQAQLPYACDGVVVKLNSLRLQEEAGFTQKFPRWAIALKYPAQEVPTRIRAIVASVGRTGAVTPVAELEPVLLAGTTVSRASLHNADRLEELDVHIGDTAIVRKAGEIIPEVVGILKELRPPDAVPYRLPSHCPECGTLLVRPAGEAITRCPNPACPAKIRGQLQHWASRDAMDIEGLGEKRVAQLVEKLGVRTVADLYRLTPEHLESLEGMGSRSSQKLVQAIQRSRQQPWERVLYGLGIPHVGVVTAQILAQHFPAPELLAQARAEDIAQIYGIGAEIAEAVVAWFADPAHQKLLQELRELGIPALPRQAAPAVSQVLAGKKFVITGTLPTLSRQQAKAWIESRGGKVTASVSRQTDYVVVGSDPGSKLKQAQALGIPLLSEAELLALDPK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TYPH_SHIB3
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RL9_BURMA
Sequence: MQIILLEKVANLGNLGDIVKVKDGYARNFLIPNRKARRATKDAIAEFEVRRAELEKVAAEKLAAAQAVGEKLNGQTFEITQKSGVDGRLFGSVTNGDVAELLKKAGYEIEKAQVRMPEGPLKMIGEHGVQVALHTDVVVDVTVNVIGDHA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GRLG_DICDI
Sequence: MKKIIFLVLFLIFIFKDIKSSYGVDLVNFKMITLLSNNFNDLGFNNMLNQGKVNVEKQLGITDTKVYIVDGYNDTKALLLPMVQNEDVDFVMCTSLGHVEACKEIAKMYEGSLTIKTQFMVRGSSNATSNLLQVTYNYASINYISGVFAGLYTKTNKIGFLSPGLLGGSADCFVYAYWLGAKQINPKIEFYYYNIGAFLNSDKTTRATAELLDMGCDVIGDTLDDFSAGNTVISRGFKALGTNGFPQREVYGENVVFSYSYNWTKIFLPIVKNALVKGKPKNNYADFNIDPTLNFYDISYGFDVPQDTKTKINDTISYLKSTPRAIHPTNCNDLMLKYAEKWNLTMSTTYDRTKCIAGSNFFFINEPFPGMTYFGYYNITNTQVKFSPSIQIGVSIVSGVLIAIVLLSMVGVYKYRASSSIRSASPIFLIFILFGALIVFGGIILWVSELNDHVCNGRLWMVTLGFSTLIGSLVVKNFRIWLIFDNPELKTVKITNYQLYPWVACCLVINIILMSILTSLGDLREVDATGIDSLGKYEFLKICKMNNSGASVLYTILAYFGALLLTGVFVSWKIRIVDIEEFNESRAIAHTLYAISFCLFVIVPLMISPLEKQSETIILSVAGLFITTAAVLIIFLPKFYRVYEYGEEGTNEMFKSKKSSNIATARAESHKSSNSGNHRTNRRGNLVSGDFTDDSESSVIEPNQEVADVTSGAVLADFTEESVSEIDENEKNHNDEIELPEINQSEQQNSEIEQPPPPPPPQQIEPDEKNQD
What are the official names of this protein?
Metabotropic glutamate receptor-like protein G.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRM1_SULIA
Sequence: MKLKEVTEGKVRIFVPDPKEYMIEGKFDPSWAPVFYNPKMTFNRDLSVIVVSLLKPKIILDALSATGIRGIRYYVESWKSEQLILNDKNSTAASLIQINVKNNGIENAKIFNKDANALLYEIKSEYIDIDPFGSPVPFILSSINATIRNGIAAFTATDLSPLEGSSRTSCRRKYDAINYKLSSSKELGLRILIGKIIREAATLEKTVHPLFSFYADYYYRLFVIVESGARKADENINKNLKYFGECPRCGFQTFVDENCKTKCPICGENFIIIGPLYIGPLHNMEFLKRMIDTYSDFNYLSSFNRIQKLLNVIEKEAKYKSVFYNISKLASKLKVSAIPPIDSILECLGDASKTHFAPTGIRTDKGYEEIIRCVKSLR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RL28_MESHJ
Sequence: MARKDQISHRGPLSGNNRSHALNATKRKFNLNLQQITLKTASGKKIRLKVSAKTKKTLRKWGHV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PXPC_BACSU
Sequence: MKVLKPGLLTTVQDIGRTGYQKYGVLASGAMDTVSLRIANLLIGNGENEAGLEITMMGPGPSFHFSKQTLIAVTGADFTLRINDEEAPLWKPVLIKENSTVSFGPCKLGSRAYLAAAGGIEVPAVMESKSTYVRGSIGGLHGRALQKEDELNIGEMSALSQTILSRLSSQLGKQGFAAPKWSVSRGRFLPLKKNPVIRVLEGKQFAFFTEESKTRFYEEAFRVTPQSDRMGYRLKGEPLELKAPLEMVSEAVSFGTVQVPPDGNPIILLADRQTTGGYPRIAHIISADLPIVSQIMPGEHVQFEPVSLQEAEALAVEREQHIKELKTRMKMEWLT
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate (PubMed:28830929).  In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A (PubMed:9334321).
What are the official names of this protein?
5-oxoprolinase subunit C, 5-OPase subunit C, 5-oxoprolinase (ATP-hydrolyzing) subunit C, KipI antagonist, Protein KipA.
What is the protein family that this protein belongs to?
Belongs to the PxpC family.
Protein: RIMM_STRT1
Sequence: MTYYNVGKIVNTQGLQGELRVLSVTDFADERFKKKSVLALFDDKDNYIMDVEVASHRKHKNFDIVKFKGLYHINDVEKYKGCSLKIAEENLTDLDDGEFYYHEIIGLDVYEGNTLIGQVKEILQPGANDVWVVKRKGKKDLLLPYIPPVVLDVDVAAGRIEVELMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDOR1_XENLA
Sequence: MPQQNLLILYGSQTGTAEDLAGRLSREAKRHHFNCRTEALDEYRVANLINEHLVIFVCATTGQGDPPDNMKNFWRFIFRRNLPHNALCQMDYAVLGLGDSSYPKFNFIAKKLHKRLNQLGACPLLPAALGDDQHELGPDAVVDPWLKDLWSKVLSMFPLRPGLEIISEDVLLPPKYSLRLLEEKVGQSELSGDAYERDFISNNTTPPSEIHPFLAPVLSNERVSAHDHFQDVRLIEFNITGSAIQFYPGDVVMVQPRNSLLHVEQFCSLLHLDPLNKVVVEPSDPESPVPMHLAALCSVQQLVERYLDICSIPRRSFFQLFCHFSPDEMEREKLKEFSCAAGQEELYSYCNRPRRTILEVLVDFPHTTRCIPATFLLELIPQIRPRAFSIASSMEALPNTIQILMAVVQYKTKLIEPRRGLCSTWLASLPPHGTERVPIWVKKGSMKFPCDPDTPVVMVGPGTGVAPFRAAIQERVANGRPGNCLFFGCRGKSKDFYFEKEWEDLGNRGYLTLFTAFSRDQEDKIYVQHRIKENSKLLWDLIGTKQGYVYIAGNAKLMPNEVTDALKWVLQLEGGMSAPDAEQYLASMEKSCRFQSETWS
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of ciapin1, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  It can also reduce the [2Fe-2S] cluster of cisd1 and activate this protein implicated in Fe/S cluster repair.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Concentrated in perinuclear structure.
Protein: MYOB2_ARATH
Sequence: MAANKFATLIHRKTNRITLILVYAFLEWSLIFFILLNSLFSYFILRFADYFGLKRPCLFCSRLDRFFDASGKSPSHRDLLCDDHALQLHSKPVEESNCGFGEFHNDLVHRGCCVEKISSSLCAPIESDFGNLDYPIGDEGQIYNGLKFPRSIFVFEEEKVGSVNLNDSQEETEEKKVPQSHEKLEDDDVDEEFSCYVSSFDCKNKEIATEKEEENRVDLPIEVETAESAPKNLEFYIDEEDCHLIPVEFYKPSEEVREISDINGDFILDFGVEHDFTAAAETEEISDFASPGESKPEDAETNLVASEMENDDEETDAEVSIGTEIPDHEQIGDIPSHQLIPHHDDDDHEEETLEFKTVTIETKMPVLNINEERILEAQGSMESSHSSLHNAMFHLEQRVSVDGIECPEGVLTVDKLKFELQEERKALHALYEELEVERNASAVAASETMAMINRLHEEKAAMQMEALQYQRMMEEQAEFDQEALQLLNELMVNREKENAELEKELEVYRKRMEEYEAKEKMGMLRRRLRDSSVDSYRNNGDSDENSNGELQFKNVEGVTDWKYRENEMENTPVDVVLRLDECLDDYDGERLSILGRLKFLEEKLTDLNNEEDDEEEAKTFESNGSINGNEHIHGKETNGKHRVIKSKRLLPLFDAVDGEMENGLSNGNHHENGFDDSEKGENVTIEEEVDELYERLEALEADREFLRHCVGSLKKGDKGVHLLHEILQHLRDLRNIDLTRVRENGDMSL
What is the function of this protein?
Membrane-anchored myosin receptors that define a distinct, plant-specific transport vesicle compartment.
What are the official names of this protein?
Myosin-binding protein 2.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass membrane protein.
Protein: ACCD_STRPC
Sequence: MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHMIYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKLQKAKETTGLHEAVLTGKAMVKEQKIALAIMDSHFIMASMGTVVGEKITRLFELAIEENLPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFAMEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDKIAHLVAFHGGGQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FARP_CHICK
Sequence: LPLRF
What is the function of this protein?
May function as a neurotransmitter or modulator.
What are the official names of this protein?
FMRFamide-like neuropeptide, LPLRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSH_NITOC
Sequence: MDNEKQASPPPAAPPLNWRYLLWIILLGIFLISWLGNAGRQAGDEITYTEFKQALHQGKIAKVTLEGQHISGTYHEAGGNIQPEGKDSKGFSTTRPPFDDPELMKLLEQKGVVVQAKSEEPSLWMQAIIGILPWFLILGLIFYVSYRMQQRMMGGGRGGPFGFGKAPVKRFREGSIGVTFEDVAGVENAKRDLREIVDYLKEPGQFKAVGAKIPKGILLVGRPGTGKTLLARAVAGEAGVPFYSISGSDFIEMFVGVGAARVRDMFKAAKEEAPSILFIDEIDSVGRARGTGLGGGHDEREQTLNQILGEMDGFAAHENVVVLAATNRPDVLDPALLRPGRFDRKVVLDLPDKKARQRVLEVHTKNVPLAADVDLERVARRTVGFSGADLANLVNEAALLTGRERKKEVDMDMFNLARDKIVLGAKRETILGEEEKKLVAYHESGHALTAWLLPEADPLHQVSIIPRGMALGVTEQAPEEERHSLSRAYLLDRLGVMLGGRISEKITFGDVTSGAESDLKQATQLARRMVCQWGMSDKIGAAAFSRSEEHVFLGRELSQPRDFSEQTAQIIDDEIRRILSEVERKTENLLQENRAKLDALAKALIEAETLNLVEVEKIFKNVKELPQEGHNEAVATGAG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: XK_PANTR
Sequence: MKFPASVLASVFLFVAETTAALSLSSTYRSGGDRMWQALTLLFSLLPCALVQLTLFFVHRDLSRDRPLVLLLHLLQLGPLFRCFEVFCIYFQSGNNEEPYVSITKKRQMPKNGLSEEIEKEVGQAEGKLITHRSAFSRASVIQAFLGSAPQLTLQLYISVMQQDVTVGRSLLMTISLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVVVLVLFTSVLKTWVVVIILINFFSFFLYPWILFWCSGSPFPENIEKALSRVGTTIVLCFLTLLYTGINMFCWSAVQLKIDSPDLISKSHNWYQLLVYYMIRFIENAILLLLWYLFKTDIYMYVCAPLLVLQLLIGYCTAILFMLVFYQFFHPCKKLFSSSVSEGFQRWLRCFCWACRQQKPCEPIGKEDLQSSRDRDETPSSSKTSPEPGQFLNAEDLCSA
What is the function of this protein?
Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane.
What are the official names of this protein?
Endoplasmic reticulum membrane adapter protein XK, Membrane transport protein XK, XK-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRPD_PECAS
Sequence: MQLSSTQPSSKTQEPSTAQDVITMQHILEKLYGANSISRQESQALFGAIIRGELEASQLAAALISMKVRGEHPDEIAGAATALLADAQPFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGLKIAKHGNRSVSSRSGSSDLLSAFGIKLDMSAQDSRQALDDLGVCFLFAPQYHLGFRHAMPVRQQLKTRTVFNVLGPLVNPARPPLALIGVYSPELVRPIAETLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNHGEIETYELTHRDFGLDTHPLSALQGGTPEENRDILASLLQGKGERAHAAAVAANVALLLRLFGQEDLRQNAQQALEVIHSGQAYQRVIALSARG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NUSB_MARMM
Sequence: MATASKESPSENRARLRRAARLSAVQALYQMEIGGLGASAVIREFREHRFGACGEAPEFVEADEDFFESLVAGVVERQADVDPAMDALLADKWRLERLDATVRAILRVGGFELLYRKDVPARVVIDEYIEVANAFFEGAEPKFINAAFDRCARGARPDEF
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: IOD3_SHEEP
Sequence: VVGEGRGALGGAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHLLGRRRRGQPEIEVELNSDGEEVPPDDPPVCVSDDNRLCTLASLRAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGFQNQHILDYARGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYSIPQHRSLEDRVSAARVLQQGAPECALVLDTMTNSSSSAYGAYFERLYIIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGPQPRRV
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine).  RT3 and T2 are inactive metabolites.  May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones.  Can regulate circulating fetal thyroid hormone concentrations throughout gestation.  Essential role for regulation of thyroid hormone inactivation during embryological development.
What are the official names of this protein?
Thyroxine 5-deiodinase, 5DIII, DIOIII, Type 3 DI, Type III iodothyronine deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: NBPFP_HUMAN
Sequence: MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDCNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
What are the official names of this protein?
Neuroblastoma breakpoint family member 26.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_CHLTR
Sequence: MTPSALFHKRLIEQFTIFLSVDRGISPLSVQAYCQDVLLFLQRASIEATDRINQESVFLFVEKCHKAKESETTLARRLIALKVFFHFLKDAKMLDQQPFIEHPKIWKRLPSILSTEEVNSLLDQPLNIPNLDTHIASRDAAILYTFYATGIRVSELCDLCIGDISDDFIRVTGKGRKTRLVPISIKAKQAIDAYLSSFRDELQKKNPSEEHVFLSIRGKKLDRSCVWKRITFYAKLVTTKRISPHSLRHAFATHLLNNHADLRIIQEMLGHSRISSTEIYTHVASESLIEKFHTYHPRDI
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_RUEPO
Sequence: MMRFLTSLVLGAALLAGAAQAQNQPLRITIDEGIIEPLPYAAPNFVPDSPAAAEYAAEIARVLAADLTGSGLFREIPSTAYISQVTSFDAPVQFADWKAINAQALITGAVSVSGNRLTVRFRLWDVFAGAELGSGLQFAGTTDGWRRMSHKVADAVYSRITGESGYFDSRVAFVSESGPKDQRRKRLAIMDYDGANVQYLTDSSSIVLAPRFSPTGDRVLYTSYQGGFPRIHILDVGQVQQRVLQSQDGTMSFAPRFSPDGQTVLFSLAQGGNTDLYAMNIASGQSTRLTSAPSIETAPSYAPDGSRIVFESDRSGTPQLYVMSAAGGEATRISFGQGRYGTPVWSPRGDLIAFTKQSKGRFHIGVMRADGSEERLLTASFLDEGPTWSPNGRVIMFTRETQGASGRAALYSVDISGRNLRPVRTPDGGSDPSWSPLQK
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RPOZ_XYLFM
Sequence: MARITVEDCLEVVNNRFELVMMASKRARQLANGVPPLIENNSEDKPTVLALREIAARKINSKMIDEIEKAERERTEREAMEWAAAEVVADEDISKSDD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RNC_TROWT
Sequence: MDGVDELLLRKFNLTLPPGLLRTAFVHKSFSFENGACQNNERLEFLGDAVLGLVVSHYLFETCPEYTEGQLSAARSYIVSGTSIAQIAKELNLGQFMLLGKGEKLAGGMDKTSLLADLLESLIGAVMVDQGFESARDFVLALVGEKLRQVGEFSVDDPKTKLQKLTRTQLVYEVVTEGPPHSRTFKASVIVNEKRFFGQGSSKKQAQVAAAMSALASLENKSS
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIAAT_XENLA
Sequence: MATLIRSKLSNVATSVSNKSQAKVSGMFARMGFQAATDEEALGFAHCDDLDTEHRQGLQMDILKTEVPTGDAPPEGDIHYQRDGTGLPPSASKDEGLCSELSSSEKPQITAWEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGETVRVRDSYVDIANACCAPRFPKLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPNLPISQKSWSIMATAVLLPCAFLKNLKAVSKFSLLCTVAHFVINILVIAYCLSRARDWAWDKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQSPREFHCMMNWTHIAACILKGLFALVAYLTWADETKEVITDNLPSTIRAVVNLFLVSKALLSYPLPFFAAVEVLEKSLFQEGARAFFPNCYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLKLMWRQLLWHQVFFDVSIFVIGSICSVSGFVHSLEGLIEAYAYNIED
What is the function of this protein?
Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals.  The transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity).  May also transport beta-alanine (By similarity).  Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (By similarity).
What are the official names of this protein?
Vesicular inhibitory amino acid transporter, GABA and glycine transporter, Solute carrier family 32 member 1, Vesicular GABA transporter, xVIAAT.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Presynapse. Note=Presents in glycine-, GABA- or GABA- and glycine-containing boutons.