PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_BORPD
Sequence: MPRMALGLAYDGSSWQGWQTQPHRQTVQDTLEAALARFAGIDGSLPTVCAGRTDTGVHAAMQVVHLDTRLERRAESWVRGVNAFLPPSIAVQWAQPVPDDFHARFSARSRTYLYLLWRGRVRPPLWAGRAGWCFQPLDVQAMRQAASALLGEHDFSSFRSSQCQARHPVRTLHRLDIDERGPFLVFTLRANAFLHHMVRNLMGALLQIGQGRQPVAWMPAVLAARDRRLAAPTFAADGLYLSAIEYPPEYKLNDTDGSGQLLSPFTFA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CLPS_CERS5
Sequence: MKLRPLQMSDKTGGTGDDTSILTKTRSKTQRPPLYKVLLLNDDYTPMEFVVHVLERFFGLSHAQAFEIMLTVHKKGLAVVGVFSFEVAETKVAQVMDFARRHQHPLQCTMEKE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PNP_BURCJ
Sequence: MFNKVVKEFQWGQHKVRLETGEVARQASGAVIVDVEDTVVLATVVGAKSAKPGQDFFPLTVDYLEKTYSAGKIPGGFFRREGRPSEHETLTSRLIDRPLRPLFPEGFYNEVQVVIHVLSVNPEIPADIPALIGASAALAVSGLPFNGPVGAARVAYIDNAYVLNPTRDQIKASSLDLVVAGTERAVLMVESEADQLSEDVMLGAVVFGHEQMQIAIDAIHELVRDGGKPEWDWQPAPKNEALIARVTELAQNDLLAAYQLRDKQARSAKLKEVYAATSAKLEEDALAAGTVAADKATVGNILFDIEAKIVRSQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQALVVATLGTKGDEQIIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALVKCLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTEQGVTALQMDIKIQGITKEIMQVALAQAKEGRMHILGKMTSAVSGANTQLSEFAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTSSDGMAEAKKRIEQITAEIEVGQVYEGTVLKLLDFGAIVNLLPGKDGLLHISEIVNERVKDINDYLKEGQQVKVKVIQTDEKGRVRLSAKALLNEAAAAAQSDTPPQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_ACIAC
Sequence: MSVAAPAHKRILLKLSGEALMGDDAFGINRATIVRMVEEIAEVTRMGVQVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATVMNALALADAMDKQGLIARVMSAIGIEQVVEPYVRPKALQYLEEGKVVVFAAGTGNPFFTTDTAAALRGAEIGAEVVLKATKVDGVYTADPKKDPTATRYTKLTFDEAMSRNLGILDATAFALCRDQKLPIRVFSIVKHGALKRVVMGEDEGTLVYA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_GEOSL
Sequence: MGEKLICNNKKAFHDFFIEERFEAGMVLKGTEVKSLRDGKANLNDSFALIRNGEIFLHNLHINPYAFGNRENHDPDRLRKLLMHKKEIEKLFGKIREKGYSVVPLRLYFKNGLAKVELGLAKGKKLYDKREDMKKKDQSREMAQALREKSKSH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AIG2A_ARATH
Sequence: MTSSDQSPSHDVFVYGSFQEPAVVNLILECAPVMVSAQLHGYHLYRLKGRLHPCISPSDNGLINGKILTGLTDSQLESLDMIEGTEYVRKTVEVVLTDTLEKKQVETIVWANKDDPNMYGEWDFEEWKRLHMEKFIEAATKFMEWKKNPNGRSREEFEKFVQDDSSPASA
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
Protein AIG2 A, Avirulence-induced gene 2 protein, Avirulence-induced gene 2 protein A, AvrRpt2-induced gene 2, Protein AIG2, Putative gamma-glutamylcyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: CTB10_CERBT
Sequence: MGSIGEPNRLLCWSIYVTKKPDQSEEDHHNHVSKVNAPMMIPFLKKYGIVRYTVKHNDAHSKPKQAALMAGQPEENVLAYDTVFEMIVKDIESIQTMQKDEEFLRTTIPDHFNFADMTRSKGSLTWIEEFTF
What is the function of this protein?
Dehydratase; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin (PubMed:29844193).  The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules (PubMed:11701851).  These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids (PubMed:11701851).  The first step of cercosporin biosynthesis is performed by the polyketide synthase CTB1 which catalyzes the formation of nor-toralactone (Probable).  The starter unit acyltransferase (SAT) domain of CTB1 initiates polyketide extension by the selective utilization of acetyl-CoA, which is elongated to the heptaketide in the beta-ketoacyl synthase (KS) domain by successive condensations with six malonyl units introduced by the malonyl acyltransferase (MAT) domain.  The product template (PT) domain catalyzes C4-C9 and C2-C11 aldol cyclizations and dehydrations to a trihydroxynaphthalene, which is thought to be delivered to the thioesterase (TE) domain for product release (Probable).  The bifunctional enzyme CTB3 then methylates nor-toralactone to toralactone before conducting an unusual oxidative aromatic ring opening (Probable).  The O-methyltransferase CTB2 further methylates the nascent OH-6 of the CBT3 product, blocking further oxidation at this site before the reductase CTB6 reduces the 2-oxopropyl ketone at position C7, giving naphthalene (Probable).  The FAD-dependent monooxygenase CTB5 in concert with the multicopper oxidase CTB12 are responsible for homodimerization of naphthalene with CTB7 installing the dioxepine moiety, finally producing cercosporin (Probable).  The fasciclin domain-containing protein CTB11 might act with CTB5 and CTB12 whereas the roles of CTB9 and CTB10 have still to be elucidated (By similarity).
What are the official names of this protein?
Dehydratase CTB10, Cercosporin toxin biosynthesis cluster protein 10.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: CCS1_PROMT
Sequence: MKKISQVLNWLSSLKIAILLLLVIAVSCAAGTLIPQQESNQFYYDNFNKNPFLGIINAKILLLFEFDHVYTSFWFLFLLIWLGLALSVCSFRRQLPILKSALNWIDYKSPSQIAKLSVAQTIVTNNCAKSLEKIKLNLKKQGWNVKETDGRIAARQGVIGRLGPILIHLGMILLMIGATYGSLNGKTIEKFLAPGRSIDLLNNNEEKGLTIELQKFQIERDPQGRAEQYKSIVNVIEPNGNNQSKEISVNYPLRYKGLTLYQADWSLAAITIKIDNSPKLQIPIKPISELGEQVWGTIIPTNKDGKNQILLTVDSELGPVNIYDNDGTLLTKLIINKEEKVKGALIKIINIIPSSGLLLKHDPGVPFVYLSFAIILIGGSLSIISTKKIWVLHENEKSMIYIGGLSNRNLSGLSKELPNLISFLET
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RISB_BORPE
Sequence: MNPYILTPDLNGEGLHIGIVRARFNEEIGQAQLQACLEELGKLGVDERDVMVVSVPGALELGVALARMAESYEFDALIALGAVIRGETYHFEVVSNESAAAISRIALETGIPVANGVLTVDTDEQAQARAAGKGADCAQVAVEMANLAAALEPEEDDEDDEDEDFDDEEDDGR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TRPF_HALS3
Sequence: MTRVKVCGLTTERDHAAAVAAGADAVGIIADVPVETPREVSVETATALRAATPPFVTSVLVTMPATPEHAVDLVRTVAPDAVQLHGDLPVGDAAYVAANTPCPVIKAVTAGDQSAARYADVVDALLVDSPPTDDAGAGGGTGRTHDWAATRAFADRVDTPVVLAGGLTPANVADAVDTVDPFAVDVASGVEARPGEKDHAAVSAFVARATATPDPTLT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: CARX_HALH5
Sequence: MKAYLVLATGETFAGEIANAKEDVYGEVVFFTGMTGYQEVLSDPSFKGQLVVFTYPLIGNYGINASDFESKEPQAAGLIVSEQSEEGHHYEATQSLQQFCDQHQLPLLTGIDTRAVVKRIREQGDMPAVITTDLSRVSFEEWVPLSERALVDEVSTKKVETFEGNGPHIVLIDYGFKQSILNSLLKRDCQVTIVPYDVSFEVVQELNPDGLLFSNGPGDPKQIEDRLPTIYRLASTYPSLGICLGHQLLALAFGADTEKLRFGHRGANQPVINLKSNRVYMTSQNHSYVVKEDSLQRTDWDATFKNINDGSIEGLTHKYLPIQTVQFHPEAHPGPSDSDEIFHSFIDDVAAKGREKTYA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: OPRL1_ARATH
Sequence: MKNFNLTHRIVMAPMARMRSYGNIPQPHVALYYCQRTTPGGLLISEATGVSETAMAYQNMPGIWRKEQIEAWKPIVDAVHSHGGIFFCQLWHAGRVSHQDCQPNGESPVSSTDKPFADDPSNEFTPPRRLRTDEIPTIINDFRLAARNATEAGFDGVEIHGAHGYLIDQFMKDSVNDRTDSYGGSLENRCRFALQVIEAVSKEIGPDRVGIRLSPFADYMESGDTDPKRLGLYMAKSLNRFEILYCHMIEPRMKTVSEIFECRESLTPMRNAFNGTFIVAGGYTREDGNKAVAEGRTDLVAYGRLFLANPDLPKRFELNAPLNK
What is the function of this protein?
Putative oxophytodienoate reductase that may be involved in the biosynthesis or metabolism of oxylipin signaling molecules.
What are the official names of this protein?
Putative 12-oxophytodienoate reductase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: PIP25_MAIZE
Sequence: MAKDIEAAAAHEGKDYSDPPPAPLVDAEELTKWSLYRAVIAEFVATLLFLYITVATVIGYKHQTDAAASGPDAACGGVGVLGIAWAFGGMIFILVYCTAGVSGGHINPAVTFGLFLARKVSLVRALLYIVAQCLGAICGVGLVKGFQSAFYVRYGGGANELSAGYSKGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSLGAAVIYNNDKAWDDHWIFWVGPFIGAAIAAAYHQYVLRASAAKLGSSASFSR
What is the function of this protein?
Water channel required to facilitate the transport of water across cell membrane.  Its function is impaired by Hg(2+).  May play a role in water uptake from the root surface.  Active as homomers.  Increased activity when heteromerization with PIP1-2.
What are the official names of this protein?
Aquaporin PIP2-5, Plasma membrane intrinsic protein 2-5, ZmPIP2-5, ZmPIP2;5, ZmPIP2a.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10A_PIG
Sequence: MSSKVSRDTLYEAVREVLHGNQRNXXKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCXLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNXDMVAKVDEVKSRVKFQMKEVLCL
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_LISIN
Sequence: MNNLKEAIKQAEHIVFLTGAGVSVPSGIPDYRSKNGLYAGMSSPEYMLSHTCLVREPEKFYQFVTENMYYPDAVPNTIHRKMAEIEADKNVTVITQNIDGLHEKAGSKKVVNFHGSLYHCYCQKCGRSVSASDYLQSDIHADCGGVVRPDVVLYEEAISESAIDQSLAAIREADLIVIVGTSFRVSPFCNLTDYRNKKARIFAVNKERISLPYPFEMIENDAVKVFAEI
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_LEPCP
Sequence: MSRSLKKGPFVDHHLLAKVEKAVAIKDKKPVKTWSRRSTILPEFIGVTIAVHNGKQHVPVYVTDQMVGHKLGEFALTRTFKGHPADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLNE_ECO45
Sequence: MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQPPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSDGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRALLPTLSAIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELTRARLAWAMDFADWPQLTGVLTAHMANVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDERKQVLMLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVSEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: SSP13_PHAJA
Sequence: KPEEDWGRES
What are the official names of this protein?
Skin secreted peptide P1-3, PjP1-3.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUB_HAMD5
Sequence: MKSKRRHSGRDVNGILLLDKPKNFSSNQVLQKVKSLFAARRAGHTGALDPLATGMLPICLGEATKFSPFLLNADKRYRVTAYLGHKTETSDAEGSVINKREITFTQPQLEEALEKFRGPILQIPSMYSALKHQGRPLYEYARQGVTLDREARRITVFDLQCLRWEGHELELEIHCSKGTYIRTIVDDLGEVLGCGAYVSDLRRLQVADYTHDSMVTLEKLEELTLKNNTLGSAIDLLLLPIESTALHLPEVNLESGAAACIKQGQPVSFFDNPTDTMVRLTEGGERHFIGIGIIDAHGRIAPKRLLRNVSDAL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: QUEE_NEIMB
Sequence: MKKINVAPENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLACGWCDTDYLTFGMMGLSDILGRLKTYAARNIIITGGEPTIQPHLDMLLDTLKAEGYFLCLETNGLNPAPPQIDYVATSPKACYAAKYENSCIETADEVRIVADGDVLAFCENMERKIRAHHYYLSPCEQDGAMNIYDTIRQIGILNSRPDASVHWQLSVQTHKWAGIE
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: RECX_STAS1
Sequence: MPKITKIEVQKKNKERFNLYLDEEFEMGIDMDTYVHFNLKKGQIVDAADMEKIQKYDQYRQAVNVAIQFLSYRKRTDHEVIQHLQKKEISESVIASVIDYCHEQRLIDHEDYANSLKNTMILTTDKGPGIFRQKLRDAGVEQTIIDVYAERYENEQPMEDIIKVANKILKQKKGPTVKRKEKLSQALMQKGYSFEIIKVVMDEMDFSQPEAELDGLLQQELEKVYNKYSRKFSGRKLINKTIEGLMRKGYKYDKIKAKLEESGIVDGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_LOTJA
Sequence: MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL21_RHIWR
Sequence: MFAIVRTGGKQYRVAAGDKIVVEKLPGEAGSTVSLGDVLLAGEGAELKDVKGLTVSAEIIAQAKGEKVIVFKKRRRHNYRRRNGHRQQHTILKILSIGGEAKAKKAPAKAKADAPAAAEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RK3_CYAPA
Sequence: MSIGILGTKLGMTQIFDEAGNAIPVTIIQAGPCPITQIKTTATDGYNAIQVGYRETKEKNLTKAQLGHLQKTNNSALRVLQEFSIESSDSIEVEKPITVELFNDNDIVNIQGYSIGRGFSGYQKRHNFARGPMSHGSKNHRLPGSIGAGSTPGRVYPGTRMAGRKGDSKITIRGLKIVKVDSERSLLIVKGSVPGKPGGLLTITQVKKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, cyanelle.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: MGST1_PIG
Sequence: MADLTELMKNEVFMAFASYATIVLSKMMFMSTATAFYRLTRKVFANPEDCSSFGKGENAKKYLRTDERVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTAILHFRLFVGARIYHTIAYLTPLPQPNRGLAFFLGYGVTLSMAYRLLKSRLYL
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Microsomal glutathione S-transferase 1, Microsomal GST-1, Microsomal GST-I.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Microsome. Mitochondrion outer membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CDN2A_MOUSE
Sequence: MESAADRLARAAAQGRVHDVRALLEAGVSPNAPNSFGRTPIQVMMMGNVHVAALLLNYGADSNCEDPTTFSRPVHDAAREGFLDTLVVLHGSGARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAGCSLCSAGWSLCTAGNVAQTDGHSFSSSTPRALELRGQSQEQS
What is the function of this protein?
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6.  This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p16-INK4a, p16-INK4.
What is the protein family that this protein belongs to?
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HDVD_CLOAM
Sequence: MLMTAEQYIESLRKLNTRVYMFGEKIENWVDHPMIRPSINCVAMTYELAQDPQYADLMTTKSNLIGKTINRFANLHQSTDDLRKKVKMQRLLGQKTASCFQRCVGMDAFNAVFSTTYEIDQKYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGDRGLAPSAQKDPDLFLRIVEKREDGIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDADGLFMIYGRQSCDTRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQSYGGCKVGVGDVVIGAAALAADYNGAQKASHVKDKLIEMTHLNETLYCCGIACSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVRLAEDIAGGLMVTMPSEADFKSETVVGRDGETIGDFCNKFFAAAPTCTTEERMRVLRFLENICLGASAVGYRTESMHGAGSPQAQRIMIARQGNINAKKELAKAIAGIK
What is the function of this protein?
Catalyzes the reversible conversion of 4-hydroxybutyryl-CoA to crotonyl-CoA.  The mechanism of the reaction seems to go through three steps: (1) the FAD-dependent oxidation of 4-hydroxybutyryl-CoA to 4-hydroxycrotonyl-CoA; (2) the hydroxyl group is substituted by a hydride derived from the now reduced FAD in an SN2' reaction leading to vinylacetyl-CoA; (3) isomerization to yield crotonyl-CoA.
What are the official names of this protein?
4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase, 4-BUDH, Gamma-aminobutyrate metabolism dehydratase/isomerase.
Protein: BICA_SYNY3
Sequence: MQITNKIHFRNLQGDLFGGVTAAVIALPMALAFGIASGAGATAGLWGAVIVGFFAALFGGTPTLISEPTGPMTVVQTAVIASLVAADPDNGLAMAFTVVMMAGLFQIAFGLLKLGKYVTMMPYTVISGFMSGIGIILVILQLAPFLGQASPKGGVIGTLQALPNLVSNVRPVETLLALMTVGIIWFMPSRWKKFAPPQLVALVLGTIISITLFGDLDIRRIGEIQAGLPALQLPVFQADQLQRMLIDAAVLGMLGCIDALLTSVVADSLTRTEHNSNKELVGQGIGNVMSGLFGGLGGAGATMGTVVNIQSGGRTALSGLIRAMVLLVVILGAAKLAATIPLAVLAGIAFKVGVDIIDWGFLKRAHHVSIKGALIMYAVIVLTVLVDLIAAVGIGVFIANILTIDRMSALQSKAVKSISDADDEILLSANEKRWLDEGNGRVLLFQLSGPMIFGVAKAIAREHNAIQECAAIVFDLSDVPHLGVTASLALENAIEEAAEKGRAVYIVGATGQTKRRLEKLQVFRFVPESNCYDDRSEALKDAVLALGPHESEDSPSSSSVQTTY
What is the function of this protein?
Low affinity, high-flux Na(+)-dependent bicarbonate transporter (PubMed:31712753).  Involved in carbone dioxide-concentrating mechanisms (CCMs) that accumulate CO(2) and improve photosynthetic carbon fixation (PubMed:31712753).
What are the official names of this protein?
Bicarbonate transporter BicA.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.