PharMolix/UniProtQA huggingface dataset:
Protein: 6PGD_ECOLI
Sequence: MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKEGVFHTEWLD
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: PAHO_ERIEU
Sequence: VPLEPVYPGDNATPEQMAHYAAELRRYINMLTRPRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_SINFN
Sequence: MSGKHVAVLMGGFSSERPVSLSSGAACADALEAEGYRVSRVDVGRDVAAVLADLRPDIVFNALHGPFGEDGTIQGILEYLEIPYTHSGVLASALAMDKAQAKHVAKAAGIPVADALIMDRREFGNAHPMKPPYVVKPVREGSSFGVVIVKEDQSHPPQVITSSEWRYGDRVMVERYIAGRELTCGVMGDVALGVTEIIPQGHAFYDYDSKYVKGGSAHVIPAQISPNIYQKIQSLAVKAHQAIGCRGVSRSDFRFDDRGEGELIWLEINTQPGMTPTSLVPEMAQHAGLQFGEFLRWMVEDASCLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_CUSPE
Sequence: MRLTPNYDYEVSSIDKKKRGYIVQIIGPVLDVPFSPGMXPSIYNALVVQGRHKQEPNVTCEVQQLLGNNRVRAVAMSDTDGLMRGMEVIDTGTPISVPVGGSTLGRIFNVLGEPVDQLGPVETNQLSPIHRSAPPFLKLDTRLSIFETGIKVVDLLAPYRRGGKVGLFGGAGVGKTVLIMELINNIAKAYGGVSVFGGVGERTREGNDLYMEMKESGVINQQKLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNRQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRSLAAKGIYPAVDPLDSTSMMLQPQIVGKQHYKTAQRVKQTLQRYKELQDIIAILGLDELSDDDRLTVARARKIERFLSQPFFVAEIFTGSPGKYVSLAETIRGCTLILSGEFDDLPEQAFYLVGTIDEVNAKAMLE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, plastid, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: XYLA_DINSH
Sequence: MSDFFAGIPAVTYEGPEARSDFAFRHYNPDEMVMGKRMEDQLRFAVAWWHSFAWEGGDPFGGPTFQRPWFGDTLDHARAKADAAFEMFRILNVPFYCFHDADIRPEGASFAETTANLEAMVDYLGQKQEASGKRLLWGTANLFSHRRYMAGAATNPDPDVFAYAAATIKTCMDATHKLGGANYVLWGGREGYETLLNTDLGREREQAGRMLQMVVDYKHKIGFEGTILLEPKPQEPTKHQYDYDVATVFSFLSEFGLQDEVKMNIEQGHAILAGHSFEHELALAREFGILGSIDMNRNDYQSGWDTDQFPNNIPEVALAYYEILRAGGFDTGGTNFDSKLRRQSLDPADLIAAHVAAMDVCAAGLKAAARMLEDGELEQRREDRYAGWRAPSAEAMLNGGKLEDCFAHVMETGLDPQPVSGGQERLEALVARYL
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FWCH2_HUMAN
Sequence: MPLPEPSEQEGESVKASQEPSPKPGTEVIPAAPRKPRKFSKLVLLTASKDSTKVAGAKRKGVHCVMSLGVPGPATLAKALLQTHPEAQRAIEAAPQEPEQKRSRQDPGTDRTEDSGLAAGPPEAAGENFAPCSVAPGKSL
What are the official names of this protein?
FLYWCH family member 2.
Protein: LUTC_BACP2
Sequence: MKGTISHRESFLTHIRQQLGKDSSSSASIQRPAWKHQVQWETNGLLSKEELVEQLKMQCQRIHTRVVETTPEEAPSALRSLMTEYGEGSVMTSGDHRFEQYGFYPMFDSLQHEGFAVTSWNAEASREENIRLAEQAAYSVVFSDYTLAESGTIVLSSHQGQGRALHFLPMMYIVCIEKSTVVPRMIQAVSTLNRLVEEGEQAKGAIHFISGPSNSADIEMNLVVGVHGPVRAVYLLIDDE
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: IF2_ECOSE
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_GEOTN
Sequence: MSAIIDVYAREVLDSRGNPTVEVEVYTEEGGFGRALVPSGASTGEYEAVELRDGDKNRYLGKGVLKAVENVNEVIAPEIIGLEVTDQVAIDRALIELDGTENKGKLGANAILGVSLAVARAAADELGLPLYQYLGGFNAKTLPVPMMNILNGGAHADNNVDIQEFMIMPVGAESFREALRMGAEIFHSLKAVLKAKGYNTAVGDEGGFAPNLKSNEEALQTIIEAIEKAGYKPGEQVMLAMDVASSELYNKEDGKYHLEGEGVVKTSEEMVAWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGHKVQLVGDDLFVTNTKKLAEGIEKGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELGHTAIYQGIRSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPD_GEOTN
Sequence: MNQEVIAKRYASALFQIALEQQQLDQIEEDIRAVRQALAENGEFLSLLSNPKLSLDKKKALVREAFAGVSAPVQHTLLLLLERHRFGIVPELAEQFIALANDARGIAEAVAYSARPLTDEELQALSDVFAKKVGKETLRIENIVDPELIGGVKLRIGNRIYDGSVSGQLERIQRQLIS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CRCB_OPITP
Sequence: MSLYLYIALGGALGSVGRFALSGLVAQHYGETFPWGTLVVNVVGSFIIGFFATLTAPEGRMLVGATGRHFVMTGVLGGFTTFSSFSLQTLNLLRDGDWGRAGGNVVGSLVLCLVAVWLGHIAAVGLNSLKGS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAT_SALA4
Sequence: MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHDARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: SYV_RHIWR
Sequence: MTIDKTFDPAAIEARWYAHWEDNGLFRPERPEAEPYTIVIPPPNVTGSLHIGHALDDTLQDVLIRHARLKGKDALWVVGTDHAGIATQMVVERQLDAKGQKRTDFTREQFIAKVWEWKEESGGTITRQLRRLGASCDWANERFTMDEGFSKAVLKVFVDLYNQGLLYRDKRLVNWDPGLKTAISDLEVETKEVQGSFWHFSYPLADGSGAISVATTRPETMLADMAVAVNPEDGRYRALIGKSVKLPITGRLIPIVADEHADPELGSGAVKITPGHDFNDFEVGKRAGFKPADMLNMLDAEAKVVQTADGLIPADYLGLDRFEARRKVVAAIEAEGRLEKVEDRVIQTPYGDRSNAVIEPWLTDQWYVDAETLAKPAIEAVRSGAIRVVPESWTKTYYNWLDNIQPWCVSRQLWWGHQIPAWYDADGQVYVAEDEAAASALAGGKALTRDSDVLDTWFSSALWPFGTIGWPDQAGQQPPEAYQAGAAGKASKLQRHYPNDVLISGFDILFFWDARMIMQGLHFMGEVPFRTLYLHGLVRAADGSKMSKSKGNTVDPLGLIDKYGADALRFTLTAMESQGRDIKLDEKRVEGYRNFATKLWNAARFAQGNGIGASTTIEPPAAELAVNRWIIAETVRTVQALDLAIADLRYDESANTIYQFVWASFCDWYLELIKPVLAEGADQGQAAETRAVAGWVLDQILVMLHPFMPFITEELWHALGRRDYDIIVAKWPMADARAIDPAAQQEIDWLIRMVGEVRAARTGLNVPPGARLPAYARGASEETRRRLAANAVAIARMARIDLAEGEAPAGGAAQVVVDEATYVLPLEGVIDLDAERARLAKGIAAAEKERDGLAARLGNPAFVEKAKPEAVEKARADHAEKSLEAEQLGAALARLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y149_PARXL
Sequence: MRAVAPIGAFATPDNFSAPVGSKLVGAAFEARAQEFLQRQRLRFVARNVACRGGEIDLVMRERDGALVFVEVRARAQRRYGGAAASIGWRKQQRIVRAAQHYLATRSSQLRDQPACRFDVIAFEAGRLVWLRDAFRADEV
What are the official names of this protein?
UPF0102 protein Bxeno_A0149.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FMT_RHIWR
Sequence: MRIAFMGTPDFAVPTLDALVAAGHELAAVYCQPPRPAGRGKALMPSPVQRRAEELGIPVRHPVTLRDADAQAVFAALALDVAVVAAYGLILPQPILDAPRHGCLNVHGSLLPRWRGAAPVQRAILAGDPTTGVTIMQMERGLDTGPMLATVETPVDGKTAGELTDELARSGAALMVEVLADLPAHPPVVQPEEGVTYAAKIDKAESRIDFAEAAGQIERQVRAFNPAPGAWFEHQGERIRILACEAVDRHGPEAPGAVIDDALTIACIDGAIRPTRVQRAGKAAMSAGELLRGFAIPAGTQLASPPRT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: COXX_THEAC
Sequence: MTSKAMLYFSYTKPKVWSLLVFVGAIGAVIAIPYFNLHYISLIVLATIAVMLGSMGAEATTNYIDKDIDAVMSRTMKRPLVTGQIKPINGLLFGLVLMFLSIAILAAFGKLYAALFMGIGLFDNVFIYSYLTKRRTPWNIILGGFSGGFPVVIGWYTVTSKFSILPWFLFLLVVVWIPIHVWSLAYRYRDDYNRAHVPMMTSIHNDRISAICISSAAIILFAFSIIPAFFRVMPMVYMILASAIAVPMIFYSIVFVRHPDRKNSLKLFIYSSPYLAIIFVLVLIFRFL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANC_CERS4
Sequence: MPPVLRTVAELRARVSDWKAAGETVGVVPTMGALHEGHLSLARRARAACDRVIVTIFVNPRQFNNPADLEKYPRTEAQDAALLASVGVDAVFAPGPEEVYPRGFATNVSVSGVSEPLEGAHRPGHFDGVATVVAKLFGMTRADRAFFGEKDWQQLMVVQRLVADLNIPVTIEGCATVREADGLALSSRNRRLSVEGRARAPALVRAMQAAAEAMRGGRAIPEALAEARAAVLAAGFETVDYLELRTADLLLPMERLQGEGRLLAAATLDGVRLIDNIPV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_TRIL1
Sequence: MKTAATIALFCAGGGLTRYYLSGWIYGLLGRAFPYGTLVVNIIGAYCIGLIMELGLRSTMLSDTLRIGLTVGFMGGLTTFSTFSYETFKLLEDGQFVMAFTNVLASVAVCLLCTWLGIITVRSLA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCSA_MICAN
Sequence: MNLVSLENFLDNTSFLVLFLTMLVYWAGAAFPSIPLLPGLGSTGVAIANLCIAALLGARWLEAGYFPISNLYESLFFLAWGVTAVHLIAEYTSRSRLVGVVTTPVAMGITAFATLSLPGEMQTSAPLVPALKSNWLMMHVSVMMLSYAALMVGSLMAIAFLIVTRGQNIELKGSSVGTGAYRLQNKLSTTLSAPIFMETANGGTTALLTPTLTAMATLSPQRLSLAETLDNISYRVIGLGFPLLTIGIIAGAVWANEAWGSYWSWDPKETWALITWLVFAAYLHARITRGWQGRKPAILAASGFVVVWVCYLGVNLLGKGLHSYGWFF
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SLMA_ECOSE
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y883_HAEIN
Sequence: MTIESILSAIDSFIWGAPLLILLSGTGLYLTLRLGFIQIRYLPRALGYLFKKDKGGKGDVSSFAALCTALAATIGTGNIVGVATAVQAGGPGAIFWMWLVALLGMATKYAECLLAVKYRVRDKNGFMAGGPMYYIERGLGIRWLAKLFALFGVMVAFFGIGTFPQVNAITHAMQDTFNIPVLVTAIIVTLLVGLIILGGVKRIATASSVIVPFMAILYVTTSLVIILLNIEKVPDAILLIIDSAFDPQAALGGAVGLTVMKAIQSGVARGIFSNESGLGSAPIAAAAAQTREPVRQGLISMTGTFLDTIIVCTMTGIVLVLTGAWNNPELAGATVTNYAFAQGLGTSIGATIVTVGLLFFAFTTILGWCYYGERCFVYLVGIRGVKLYRLAYIMLVGLGAFLHLNLIWIIADIVNGLMAFPNLIALIGLRKVIIEETKDYFQRLKINHYDQDEVIK
What are the official names of this protein?
Uncharacterized transporter HI_0883.
What is the protein family that this protein belongs to?
Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB_NITEC
Sequence: MIESDRIITASPFSSQEEVIERALRPVQLDDYVGQEKIREQLKIFIEAARQRQEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRHTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGVAARSVKIDLPSFTLVGATTRAGMLTNPLRDRFGIVSRLEFYTSDELSKIVTRSAGLLDVDITADGAREIACRSRGTPRIANRLLRRVRDFAEVRANGRIDRQVADAALQMLDVDAAGLDVLDRKLLLAVLEKFGGGPVGVDNLAAAINEERDTIEEVLEPYLIQQGFLQRTPRGRMATTMTYQHFDIIPLQQAATPGLFNPD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AERA_AERSO
Sequence: MMNRIITANLAFLASSLMLAQVQAAEPVYPDQVKWAGLGTGVCASGYRPLTRDEAMSIKGNLVSRMGQWQITGLADRWVIMGPGYNGEIKQGTAGETWCYPNSPVSGEIPTLSDWNIPAGDEVDVQWRLVHDNDYFIKPVSYLAHYLGYAWVGGNHSPYVGEDMDVTRVGDGWLIKGNNDGGCSGYRCGEKSSIKVSNFSYTLEPDSFSHGQVTESGKQLVKTITANATNYTDLPQQVVVTLKYDKATNWSKTDTYSLSEKVTTKNKFQWPLVGETELAIEIAASQSWASQKGGSTTETVSVEARPTVPPHSSLPVRVALYKSNISYPYEFKAEVNYDLTMKGFLRWGGNAWYTHPDNRPTWEHTLLLGPFRGQGEQHPLPVDKRYIPGEVKWWDWNWTISEYGLSTMQNNLGRVLRPIRSAVTGDFYAESQFAGDIEIGQPQTRSAKAAQLRSASAEEVALTSVDLDSEALANEGFGNVSLTIVPVQ
What is the function of this protein?
Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death.  The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter.
What are the official names of this protein?
Aerolysin, Hemolysin.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Secreted as a soluble precursor.
Protein: MNTP_DESVV
Sequence: MNTLECLAVAVALAMDAFAVAIATGIRLREVSPRQTFRLAFHFGLFQALMPVAGWTLGLTVRGYIEQWDHWLAFGLLLYIGVRMMREAFEETEENDDRCDPTRGLTLIMLAVATSIDALAVGLSLSVLGIDIVTPAIVIGVVCLLFTATGLHLGRMLSRAESLGRRAALAGGVVLIGIGLRILYEHGVFDTAATLARSVLG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASNA_BACCR
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTVEYLQKTVQTIYGIFKDLEDHLFEKYPFLGKYLPEEIVFVTSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRAADYDDWKLNGDILFWHPVLQSSFELSSMGIRVDSKSLDEQLTKTGEDFKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_LIMF3
Sequence: MTELDSLWEAIQNSFRKSKGDTTYKNLIAPAKPLDFANGRLRIQLPSQYHRDFWEQLTDQVVEIVYQRTGQEIRPDYVLATDPTPLAQTPPRPQSTFKEETPLNPEYTFQTFIEGRSNMMAYASAFAASESPGDQYNPLLIYGGVGLGKTHLMQAIANNMKFHNPSVRIKYVTSENFMNDFVNSIKSGTQEEFRREYRDLDALLVDDIQFFASKGETQTEFFNTFNVLYDNKKQIVLTSDKDPREIPNLTERLVSRFMWGVPVEITSPALETRIAILKSKAEEEHLDVPNDVLNFVAQRINTNVRELEGALMRIRVFSELHQQPITLKLATEALQGMVANTETTVTIDLIQKRVATYYNINQSDITGKKRTKNIVVPRQIAMYLSRELTDNSLPKIGKEFGGKDHTTVLHAIDKIERQVQEDARLQGDLVKLKNDLQA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_DICNV
Sequence: MNWAKRSAFFLISVACFLADYYSKYWALTELGARKIVVNTYMNFILAFNHGAAFSFLARAGGWQRWLFAGFAGIVALWLIMTLLTKSHHWLMSVSYACILGGAVGNLYDRVVYGYVIDFIQWHYRTFYWPVFNLADVAITLGVILMLIAELHRR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_MYCAP
Sequence: MNLFYNLSLKANTLLSAQSGGIKDELKDKFKTLFPTWPMFLATLIAFILVVLILWFLLHKPIKKAMKARQDYIQKNIDEAKLTNDISKQKLNEANKRLAEAYSEADELIKNAKIHGESVIDEYTHKAKNKSKRIIEKAHMEIESERQKMVDDSKSNIAKAAIEISKKIMQKEVTKESQDEVIKNFLKDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.