PharMolix/UniProtQA huggingface dataset:
Protein: GARL_SALG2
Sequence: MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALSHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: Y1287_RHOPT
Sequence: MAGHSQFKNIMHRKGRQDAQRSKLFSKLAREITVAAKLGTPDPAMNPRLRAAVLAARAENMPKDNIERAIKKAIGGDSENYDEIRYEGYGPGGVAVIVEALTDNRNRAASDIRSFFTKSGGNLGETGSVSFMFDRTGIIEYDADKASADDMLDAAIEAGADDVVSSEAGHEIYASQETFRDVAKALEAKFGEARKAAVIWKPQNTVAVDDETGEKLFKLMDALNDHDDVQNVYANFEVSDALMAKMAG
What are the official names of this protein?
Probable transcriptional regulatory protein Rpal_1287.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_HALS3
Sequence: MFKDRPDRSDEVVLVGRSNVGKSTLMRAVTGHQVPTGQKPGVTRQPNHFDWASEDFMLTDLPGFGYMQGVEDGHEEAIKTEVVRYVESHADNIMVGVLVLDGKAAVDIIDRHSGGDEIPHVVELYYLLEELGVQPVVAVNKMDKVDDRDERLNDIADRLGLYPPWEQWQDVIAPITAKKDRIAALEDAVNSHFDAAKRDDLKQFFS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NDHL_PROMP
Sequence: MESIFNNSFATLVAYVGIVSIYLLVIPLILFYWMNNRWNVMGKFERLIVYGLVFLFFPGLILFSPFLNLRLRGDSKG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FRDA_SHEFR
Sequence: ADNLAEFHVQNQECDSCHTPDGELSNDSLTYENTQCVSCHGTLEEVAETTKHEHYNAHASHFPGEVACTSCHSAHEKSMVYCDSCHSFDFNMPYAKKWQRDEPTIAELAKDKSERQAALASAPHDTVDVVVVGSGGAGFSAAISATDSGAKVILIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDTMKGGQNINDPALVKVLSSHSKDSVDWMTAMGADLTDVGMMGGASVNRAHRPTGGAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGYYWVKADAVILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAGGALKDMQYIQAHPTLSVKGGVMVTEAVRGNGAILVNREGKRFVNEITTRDKASAAILAQTGKSAYLIFDDSVRKSLSKIDKYIGLGVAPTADSLVKLGKMEGIDGKALTETVARYNSLVSSGKDTDFERPNLPRALNEGNYYAIEVTPGVHHTMGGVMIDTKAEVMNAKKQVIPGLYGAGEVTGGVHGANRLGGNAISDIITFGRLAGEEAAKYSKKN
What is the function of this protein?
Catalyzes fumarate reduction using artificial electron donors such as methyl viologen.  The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO).  This enzyme is essentially unidirectional.
What are the official names of this protein?
Fumarate reductase flavoprotein subunit, Flavocytochrome c, Flavocytochrome c3, Fcc3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: LPXD2_GLOVI
Sequence: MKLSDISAKLGCALEGDGQVDIVGIAGIEEAEAGHLTFLSNPKYKAKLRHTKASAAIVPADFEASAAWPLPLLRHANPYLTFAHAIELFYSPPPAPHGVHPTAVVAPTAVCGHNVRIGASSVIGEGVVLADGVTVYPNCTIYPGVRIGRNSTIHSNCVVREHVVIGEDCIVQNGAVIGADGFGYAKQADGTWYKIVQSGSVVLENRVEIGACTTVDRATIGETRIKSGSKLDNLVMIGHGSSVGENTLLCGQVGLAGSSTVGRNVMLAGQVGVAGHLHIGDNVVATVKSCIWKSVEANQVLYGNIPASDSHTWLKASAVFRQLPHMQKSVQQMQKRIAVLEEPFKTNGKSGQADAPPKVALECHGTTGDAPQG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYFB_SALTY
Sequence: MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVCGAPNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEISVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGPIIDVSNEATLPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEPIQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNRVRIFETGLRFVPDTQANLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKLADRIVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_MICAN
Sequence: MKKISILGSTGSIGTQTLDIVTDHPDKFQVVGLATGNNIQLLSEQIRQFRPQIVAINNESQLEDLKSLISDLDYTPIILAGKEGVIEVARYGDSESVVTGIVGCAGLLPTIAAITAGKDIALANKETLIAGGPVVLPLVEKHRVKLLPADSEHSAIFQCLQGVPTGGLKKIILTASGGAFRDLPVEKLPQVTVADALKHPNWSMGRKITIDSATLMNKGLEVIEAHYLFGVDYNAIDIVIHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSWPERIYTDWEPLNLVKAGSLTFKEPDHQKYPCMGLAYAAGRAGGAMPAVLNAANEQAVALFLEEKISFLDIPRVIEKVCDRFAIHNTSTPSLDDILAADNWARQEVSNCLIANPV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: AT2A1_RABIT
Sequence: MEAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFMYAEDGPGVTYHQLTHFMQCTEDHPHFEGLDCEIFEAPEPMTMALSVLVTIEMCNALNSLSENQSLMRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLKALDLTQWLMVLKISLPVIGLDEILKFIARNYLEDPEDERRK
What is the function of this protein?
Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum.  Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:10914677, PubMed:11438520, PubMed:15189864, PubMed:29081402, PubMed:18075584, PubMed:24270570, PubMed:23996003).  Contributes to calcium sequestration involved in muscular excitation/contraction.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SERCA1, SR Ca(2+)-ATPase 1, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ACBP1_ARATH
Sequence: MADWYQLAQSIIFGLIFAYLLAKLISILLAFKDENLSLTRNHTTQSEYENLRKVETLTGISGETDSLIAEQGSLRGDEDESDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSLVYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALVDKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESEWSWMREKKDSN
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with very high affinity.  Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA.  Confers tolerance and binds to lead ions Pb(2+), probably by promoting lead translocation from roots to shoots.  May function as an intracellular carrier of acyl-CoA esters (By similarity).  Modulates negatively sterol synthesis during embryogenesis and gametophytes development via interactions with SMO1-1 and SMO1-2; sterols serve as lipid modulators for gene expression of homeodomain-leucine zipper IV transcription factors (PubMed:28500265, PubMed:29288621).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 1, Acyl-CoA binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, cell wall. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Detected in the cell walls of the outer integument cells at the seed coat.
Protein: G6PD1_MYCTU
Sequence: MVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLYAGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSPWLPRGTDA
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase 1, G6PD 1.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: CYNS_BURA4
Sequence: MTQSQVTPNAREALTETIVDAKVRKNLTFEAINEGTGLSLAYTTAALLGQHALPEKAAKLVAERLGLDDDAVRLLQTIPVRGSIPGGVPTDPTVYRFYEMVQVYGSTLKALVHEKFGDGIISAINFKLDIQKVPDPEGGERAVITLNGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: NAT14_MACFA
Sequence: MAPSHLSVREVREDEKPLVLEMLKAGVKDTENRVALHALTRPPALLLLAAASSGLRFVLASFALALLLPVFLAVTAVKLGLRARWGSLPPPGGLGGPWVAVRGSGDVCGVLALAPGTNAGDGARVTRLSVSRWHRRRGVGRRLLAFAEARARAWAGGMGEPRARLVVPVAVAAWGVAGMLEGCGYQAEGGWGCLGYTLVREFSKDL
What is the function of this protein?
May act as a transcription factor regulating the expression of coproporphyrinogen oxidase by binding to a promoter regulatory element.
What are the official names of this protein?
Probable N-acetyltransferase 14.
What is the protein family that this protein belongs to?
Belongs to the camello family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MPC1_CAEEL
Sequence: MSRVISKVTTYFKQHSTAEWKHYFLSTHFWGPVANWGLPLAALGDLKKNPDMISGPMTSALLIYSSVFMRFAWHVQPRNLLLFACHFANFSAQGAQLGRFVNHNYLHYVEDPVHHKLMMKKEVLEHEHDAEVISKAH
What is the function of this protein?
May mediate the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Probable mitochondrial pyruvate carrier 1, MPC1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PLAO1_PLAOI
Sequence: MKLSFSLCIFFLISADIVQGTCKKVAQRSPNVNYDFCVKSLGADPKSHSADLQGLGVISANLAIQQGSKIQTFIGRILKSKVDPALKKYLNDCVGLYADAKSSVQEAIADFKSKDYASANVKMSAALDDSVTCEDGFKEKKGIASPVTKENKDYVQLTAISLAITKLLGA
What are the official names of this protein?
Putative invertase inhibitor, Pollen allergen Pla or 1, Pollen allergen Pla or 1.0101.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
Protein: PVK1_CYRPO
Sequence: GSTGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, CyrPo-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FUMC_STAES
Sequence: MSVRIEHDTFGEIEVPEDKYWGAQTERSKRNFPVGKEHMPIQVIYGFAQLKRGAALANHELGKLSDEKKNAIVYACDRILNGELDNHFPLVIWQTGSGTQSNMNVNEVVSYVANEYLKKHGSKETIHPNDDVNKSQSSNDTFPTAMHVALFHEVETKLEPALNHLRQTFKEKEDQYQSIIKIGRTHLQDATPIKLGQEISGWRYMLEKCEQLLSESKKHILNLAIGGTAVGTGINAHPEFGHKVAKYISQNTGYAFVSSENKFHALTSHDEIVQLHGTLKALATDLMKIANDIRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTTVGIASSQGNFELNVFKPVIMHNTLQSIYLLADGMNTFNKNCAIGIQPIEENINNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIESGYVTESQFEEWIKPEDMVDPH
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_SODGM
Sequence: MTKSELIERLAGQHAHIQAKVVEDAVKEMLEHMATTLASGERIEIRGFGSFSLHYRAPRIGRNPKTGDRVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MNMA_OCEIH
Sequence: MKNNKDTRVVVGMSGGVDSSVAALLLKQQGYDVVGIFMKNWDDTDEFGVCTATEDFDDVVRVCNQLEIPYYSVNFEKQYWDKVFTYFLDEYKAGRTPNPDVMCNKEIKFKAFLDHALALGADYLATGHYAQVRRDKNGRVEMLRGNDENKDQTYFLNQLSEDVLDKVMFPLGHLPKSEVRKIAKEHELVTAEKKDSTGICFIGERNFKEFLSEYLPAQPGEMQTLDGIVKGSHDGLMYYTLGQRQGLGIGGSGDPWFVVGKNLTDNILYVGQGYENDYLYSNALVATDINWIQPDKISDTFNCTAKFRYRQQDSEVNVTIKSENEVYVAFKEDQRAITPGQAVVFYDGEVCLGGGTIDTIIKNDHKLDYVG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ACTP2
Sequence: MATLEQKLEELVSDTIESMGFELVGIECQRAGRFLTVRLYIDKEGGVTIDDCSDVSRQVSAILDVEDPIADKYNLEVSSPGLDRPLFTLAHYQRFIGQEIVIHLRIPMFDRRKWQGKLESVEGDLITLTVDNETRQFAFGNIQKANLVPVFNF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_HAES1
Sequence: MYLSDFYFDLPDELIARYPKRERSSSRMLQLNGQNGELFHRTFSDVADLINEGDLLIFNNTRVIPARMFGRKASGGKIEVLVERVLNEHHFLAHIRSSKSPKENTVLFLGEDKLGEGKGVEMLMKARHENLFELELSDKSTALLDILQKIGHMPLPPYIDRPDEDADKERYQTVYNKVPGAVAAPTAGLHFDDELLTQLKNKGVNFAFVTLHVGAGTFQPVRVENIEDHKMHAEYVEVPQEVVDAVLATKAKGKRVIAVGTTSVRSIESAALFAEENNSTHLLEPYFSDTSIFIYPGKKFRVIDCLITNFHLPESTLIMLVSAFAGYQHTMNAYKSAVENRYRFFSYGDAMFITKA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STALP_PONAB
Sequence: MDQPFTVNSLKKLAAMPDHTDISLSPEERVRALSKLGCNVTISEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQEYLQSKNQYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVNRALTPAATLSAVQNLVVEGLRCVVLPKDLCHKFLQLAESNTVRGIETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDVENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLSEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVKDIKIIVLDLR
What is the function of this protein?
Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex.  Does not cleave 'Lys-48'-linked polyubiquitin chains.
What are the official names of this protein?
AMSH-like protease, AMSH-LP, STAM-binding protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67C family.
Protein: PPR3E_HUMAN
Sequence: MSRERPPGTDIPRNLSFIAALTERAYYRSQRPSLEEEPEEEPGEGGTRFGARSRAHAPSRGRRARSAPAGGGGARAPRSRSPDTRKRVRFADALGLELAVVRRFRPGELPRVPRHVQIQLQRDALRHFAPCQPRARGLQEARAALEPASEPGFAARLLTQRICLERAEAGPLGVAGSARVVDLAYEKRVSVRWSADGWRSQREAPAAYAGPAPPPPRADRFAFRLPAPPIGGALLFALRYRVTGHEFWDNNGGRDYALRGPEHPGSGGAPEPQGWIHFI
What is the function of this protein?
Acts as a glycogen-targeting subunit for PP1.  PP1 is involved in glycogen metabolism and contributes to the activation of glycogen synthase leading to an increase in glycogen synthesis.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3E.
Protein: HEY1_CANLF
Sequence: MKRAHPDYSSSDSELDETVEVEKESADENGNLSSALGSMSPTTSSQILARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHAGLGHLPWGSAFGHHPHVAHPLLLPQSGHGNTGTSASPTDPHHQGRLAAAHPEAPALRAPPSGGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFGSFHLLSPNALSPSAPTQAANLGKPYRPWGTEIGAF
What is the function of this protein?
Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'.  Downstream effector of Notch signaling required for cardiovascular development.  Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development.  May be required in conjunction with HEY2 to specify arterial cell fate or identity.  Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification.  Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3.
What are the official names of this protein?
Hairy/enhancer-of-split related with YRPW motif protein 1, Hairy and enhancer of split-related protein 1, HESR-1.
What is the protein family that this protein belongs to?
Belongs to the HEY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ODP2_SCHPO
Sequence: MLSANMLRRMHHGVAVTRMLLVSNGKVQVKKSALYPVMAKLARTYATKNYPAHTVINMPALSPTMTTGNIGAFQKKIGDKIEPGDVLCEIETDKAQIDFEQQDEGYLAKILIETGTKDVPVGKPLAVTVENEGDVAAMADFTIEDSSAKEPSAKSGEEKSAPSSEKQSKETSSPSNVSGEERGDRVFASPLARKLAEEKDLDLSQIRGSGPNGRIIKVDIENFKPVVAPKPSNEAAAKATTPAASAADAAAPGDYEDLPLSNMRKIIASRLAESKNMNPHYYVTVSVNMEKIIRLRAALNAMADGRYKLSVNDLVIKATTAALRQVPEVNAAWMGDFIRQYKNVDISMAVATPSGLITPVIRNTHALGLAEISTLAKDYGQRARNNKLKPEEYQGGTFTISNLGMFPVDQFTAIINPPQACILAVGTTVDTVVPDSTSEKGFKVAPIMKCTLSSDHRVVDGAMAARFTTALKKILENPLEIML
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DHSC_RICFE
Sequence: MTKTKQEIYNKRPTSPHLSIYKLQISSTLSILHRMTGVALFFAVSILAWWLILSKYDNNYLQFANCCIIKICLVAVSYAWFYHLCNGIRHLFWDIGYGFSIKAVNITGWCVVVCSILLTMLLWV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b556 subunit, Cytochrome b-556.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UNG_ECOUT
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIFO_VIBCH
Sequence: MKKIAWSLGILVTIGALCAIVWPSWYPSRPLVTTPSQADIQADQSSPRDLLEYFLSGLGETSLPVIQQQVQRYEQENQGLLIDSSLFAQYVQYKAALSELTLPQASGGLSTQEWWQLHQSLLDLQARYFSAEQQALFAEENRLRELAIEKRRIYEQYGQSEEAQRAWQALLLDQPDFIQRSEATAQLLPQLTQAGQGDTQQRYLARVALVGEQGAQRLAELDDSRATFEQQFQDYYQARAAILVRNELSASEQQTQIQQLREQHFAPEQWRRIDALERLKDNGE
What is the function of this protein?
May be involved in the folding of the extracellular lipase during its passage through the periplasm.
What are the official names of this protein?
Lipase chaperone, Lipase activator protein, Lipase foldase, Lipase helper protein, Lipase modulator.
What is the protein family that this protein belongs to?
Belongs to the lipase chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.