PharMolix/UniProtQA huggingface dataset:
Protein: FTSH_ACIC1
Sequence: MSREVTSGLPQDKPTGSAPPPPPPWRRWLLPIGLLVSLVLLFTFPMRPSSGKTLTYSEFLTALHHHDIKTITIHSDGEASGQFADGRPYSTTIPIGLAGSQLLNELENNGVQISARPPGPSLASQVLAGVLSFLPFLLLLGLFAYSGRRAGAGFLAGLPGIGRARAKIFTTERPQTRFSDVAGYDGVKAEIAEVVDFLRSPERYRRAGAAIPRGVLMVGPPGTGKTLMARAVAGEAGVPFLSVTGSSFVEMFVGVGASRVRDLFEEARKHAPCIVFVDEIDAIGQRRAGAGTIVANDEREQTLNQLLAEMDGFEPAQGVVVLAATNRPEVLDPALLRPGRFDRQVTVPLPSQADRAAILRVHCRNKRLAPDVDLDAVARATPGFSGAELANLVNEAAIAAARAGRRDLTAEDFRYARDRIILGRREDSNVLLPSERHAVAVHEAGHAVVAACSENADPVERVTILPAGRALGVTFQLPLAERHLYSESYLRDSLAVRLGGRAAELEILGEASTGAVNDLSSATELALRMVREYGLSPRLGPVSYPVGGSMYLPGGQELTPRPYAEATQQRIDQEVADLLRDAEERARDIIRRNRQAVDELASLLLEQESVDGAVVYQLVGRPVPTPEEHREAAARHVRRPGIAAATGASMAGGSEPRTAASSDDLL
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: 1433B_BOVIN
Sequence: MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLQLLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negative regulator of osteogenesis.  Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.  Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
What are the official names of this protein?
14-3-3 protein beta/alpha, Protein kinase C inhibitor protein 1, KCIP-1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: YG161_YEAST
Sequence: MSGYFNHLSSNAHFANIQADQGFIGDATGTSSDHGSSGMVDFALQLGELSLEEKILKEFTLFQSKNMDLLQETATACPSTNPSLRQSRIQGW
What are the official names of this protein?
Uncharacterized protein YGR161W-C.
Protein: XERDL_STRP1
Sequence: MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLLYQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINTDIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLSQILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFILKEKLAGKSIIELSDILGLKSPMTLEKYYKS
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_SULIA
Sequence: MEFKVIAEYFDKLEKISSRLQLTALLADLLSKSDKAIIDKVVYIIQGKLWPDFLGYPELGIGEKFLIKAISIATNTDENSVENLYKSIGDLGEVARRLKSKQQSTGILGFLGTSSKESLKVDEVYSTLSKVALTTGEGSRDLKIRLLAGLLKKADPLEAKFLVRFVEGRLRVGIGDATVLDAMAIAFGGGQSASEIVERAYNLRADLGNIAKIIVEKGIEALKTLKPEVGIPIRPMLAERLSNPEEILKKVGGSALVDYKYDGERAQIHKKDDKIFIFSRRLENITSQYPDVVEYISKYTEGKEFIIEGEIVAVDPESGEMRSFQELMHRKRKSDIYEAIKEYPVNVFLFDLMYYEDVDYTTKPLEVRRKLLESIVKPNDYVKIAHHIQVNNVEDLKSFFYRAISEGGEGVMVKAIGKDAIYQAGARGWLWIKLKRDYQSEMADTVDLVVVGGFYGKGKRGGKISSLLMAAYNPKTDTFESVCKVASGFSDEQLDELQKKLMEIKRDIKHPRVNSKMEPDIWVEPVYVAEIIGAEITISPLHTCCQDVVEKDAGLSIRFPRFIRWRDDKSPEDATTTDEILEMYNKQPKKKIESPPIDESV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: MNMG_METS4
Sequence: MQRIDRTRFDVIVVGGGHAGVEAAAAAARLGAATALVTHRRATLGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADRAGIQFRLLNRRKGPAVRGPRSQADRKLYARAMQEALAATPNLSLIEGEAHDLAVVEGRVTGIVLADGRALPCAAVVLTTGTFLRGLIHIGERTMPAGRVGEAPALGLAATLDRHGFGLGRLKTGTPARLDGRTIDWAGIEKQAADDEPVPFSSLTDRITTPQIECGVTRTTQAVHDLIRANLHRSPMYSGGITSRGPRYCPSIEDKVVRFGDRDGHQIFLEPEGLDDPTIYPNGISTALPEEVQRAVLRLIPGCERAAMLRPGYAIEYDYVDPRELDPTLQTRRVAGLFLAGQINGTTGYEEAAGQGILAGINAARLAAGSALAVLDRAESYIGVMIDDLVTHGVSEPYRMFTSRSEYRLSLRVDNADERLTGRGIALGCVGAARARHFAESQQALAAARARLDALAITPSEAARHGLALNRDGIRRSAFQLLSYPEIDWPRLAAIWPELAAVPPRVAERLRTDAAYAVYLDRQRSDIAAFRRDEAVRLPASLDYGRIAGLSNELRLKLDCVRPHTLGQAARIEGVTPAALTLLAAHARRADAAAPAEA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_BRUSI
Sequence: MTNSSDDFTQSAEPFKLFAEWLADAAKSEPNDPNAVALATVDPDGLPNVRMVLLKDFDETGFVFYTNYESKKGQEILSAEKAAMCFHWKSLRRQVRVRGPVEKVSDAEADAYYASRPRGSRIGAWASKQSRPLESRFALEKAVAEYTAKYAIGDIPRPPYWSGFRIRPVSIEFWHDRPFRLHDRVLFTRPTPEGDWNKDRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: REV_HV2D2
Sequence: MTAREGDLQKELRLLHLLHQTNPYPQGPGTASQRRNRRRRWKRRGLQILALADRIHSFSTAPAEEPLNLAIQRLQNLTVEDLPNPPPNLNQSPTTQAPGCVPPVWDQLVPRSAPSGSKGYGRNSCECRRDLMGGSQESGESNHRDPQENQTRT
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: RK14_OENEH
Sequence: MIQPQTRLNVADNSGARELMCIRIIGASNRRYAHIGDIIVAVIKEALPSTSLERSEVVRAVIVRTCKELKCDDGIIIRYDDNAAVVIDQEGNPKGTRVFGAIAHELRELSFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GSA_HELAH
Sequence: MELLHSINDFNEAKQVIVGGVNSPVRAFKSVKGTPPFILKGKGAYLYDVDNNHYIDFVQSWGPLIFGHADEEIEENIIKALKKGTSFGAPTELETTLAKEIISCYDGLDKVRLVNSGTEATMSAIRLARAYSQKDDLIKFEGCYHGHSDSLLVKAGSGCTTFGSPSSLGVPSDFSKHTLVARYNDLNSVQECFQKGNVGCVIIEPIAGNMGLVPAQKEFLVGLKALCEKYQAVLILDEVMSGFRASLSGSQEFYGVVPDLVTFGKVIGAGLPLACFGGRAEIMDLLSPIGGVYQAGTLSGNPLAVCAGLSTLYKIKRDKTLYSRLNALAIRLTQGLKKSAKSYNIALQTLNRGSMFGFFFNENAVCDFDDALKSNTEMFAKFHQKMLFKGVYLACSSFETGFICEPMTEEMIDLVIVKANESFDEIIKGV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_AGRVS
Sequence: MERAEKREFVTELNEVFKASGSVVVAHYAGVTVAQMNDFRSKMRAAGGTVKVAKNRLAKIALQGTESEGMTDLFKGQTLIAYSVDPITAPKVVMDFAKTNDKLVVLGGSMGTTTLSVDAVKSLATLPSLDELRAKLVGMIQTPATRIAGVVQAPAAQLARVFAAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AAEA_YERPS
Sequence: MSTFSLKIIRVGITVLVVVLAVIAIFNVWAFYTESPWTRDAKFTADVVAIAPDVSGLLTEVPVKDNQLVQKGQILFVIDQPRYQQALAEAEADVAYYQTLAAEKQRESSRRHRLGIQALSQEEIDQASNVLQTVQHQLAKAIAVRDLARLDLERTTVRAPAEGWVTNLNVHAGEFINRGATAVALVKKDTFYILAYLEETKLEGVKPGYRAEITPLGSNRILHGTVDSISAGVTNSSSSADSKGLATIDNNLEWVRLAQRVPVKIHLDSEDQQYLYPAGTTATVVITGPNDRDPHQASPMTKLMHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RDRP_I78A7
Sequence: MDVNPTLLFLKIPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDRLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEIEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKRMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFSEIMKICSTIEELRRQKQ
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: CB5D1_HUMAN
Sequence: MPRRGLVAGPDLEYFQRRYFTPAEVAQHNRPEDLWVSYLGRVYDLTSLAQEYKGNLLLKPIVEVAGQDISHWFDPKTRDIRKHIDPLTGCLRYCTPRGRFVHVPPQLPCSDWANDFGKPWWQGSYYEVGRLSAKTRSIRIINTLTSQEHTLEVGVLESIWEILHRYLPYNSHAASYTWKYEGKNLNMDFTLEENGIRDEEEEFDYLSMDGTLHTPAILLYFNDDLTEL
What is the function of this protein?
Radial spoke stalk protein that binds heme under oxidizing conditions.  Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway.
What are the official names of this protein?
Cytochrome b5 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
Protein: FTSA_STRP2
Sequence: MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKDGIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEITDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYTGPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVATIRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEVIGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMVELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSHQPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGLIGSMFDE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring (By similarity).  Increased expression restores growth to a PBP2b (penA) deletion strain as well as mreCD and rodA deletions, but not gpsB or rodZ deletions.  Does not restore wild-type cell morphology to the penA deletion (PubMed:28941257).
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphiphatic helix.
Protein: NTN2_PHYNA
Sequence: GLKDMIKNLAKEAAVKLAGAVINRFSPQPQ
What is the function of this protein?
Probably has antibacterial activity.
What are the official names of this protein?
Nattererin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_LEPIN
Sequence: MNDTIAAVSTSSGAGAIGIIRMSGPEALTISSSFLFSKNKFLSPSEILPRTAIQCVFQIGDRKIDQILFFYFKSPNSYTGEDLCEFHFHGNPILLREALDAIFRAGARPAKQGEFSRRAFLNEKLDLTEVEAIGRLISARSRFELELAQKNVFGEVTRFTSNLRSQLISLKAECEAEIDFSTEDLTYESLEERKTRIENVKSLCQTLISKSSSAEKLIQQFRIVLYGEPNTGKSSLMNVLLGKERSIISEIPGTTRDYISEEILLEGIPVRLVDTAGVRETTDHIEKLGIERSEKEFQSADIRLFLVDVSKKENWKEFINKSRERLEGSILIANKIDILNSSWDRNLFSDVKDLIVLEISCKTKEGISNLLDAIKERTGKLGHSEDYVLLEERQRYHFETIVRCLDKTLHLLKEGAPAEIYIQEINYALAEIGEVNGKVDTEEVLGRIFSKFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_HAHCH
Sequence: MNVAETYEPTPIIFTDNAAAKVKSLIEDEGNDELSLRVFVTGGGCSGFQYGFSFDEAVNEDDTIVEKDGVRLVVDSLSYQYLVGAEVDFREGLEGAQFVIKNPNASTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RS2_AGRFC
Sequence: MALPDFSMRQLLEAGVHFGHQTHRWNPKMKPYIFGDRNNIHIIDLAQTVPMLSRALQVVSDTVARGGRVLFVGTKRQASEIIADSAKRSAQYYVNSRWLGGMMTNWKTISNSIQRLRKVDEILNSEGSGYSKKERLTLEREREKLEKALGGIRDMGGVPDLMFIIDTNKEKIAIEEAKRLGIPVVAIIDSNCDPDHIDYPIPGNDDASRAISLYCDLIARAAIDGIARQQGASGRDIGASEEAPIEPALEDEAGA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RNPA_THEMA
Sequence: MTESFTRRERLRLRRDFLLIFKEGKSLQNEYFVVLFRKNGLDYSRLGIVVKRKFGKATRRNKLKRWVREIFRRNKGVIPKGFDIVVIPRKKLSEEFERVDFWTVREKLLNLLKRIEG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: WTR23_ARATH
Sequence: MASITLRRRDAVLLTAMLATETGNVAMNTLFKAATSKGLNSYTFLIYSYLIGSIVLLPSHIFSYRSRSLPSLSLSILCKIGVLGLLGSTYLITGFIGIEYSNPTLASAISNINPAITFILAIIFRMEKASFKEKSSVAKMVGTIVSLVGALVVVLYHGPRVFTPSSPPFPQLRQLLLPLSSSNSDWIIGGCLLAIKDTLVPVAFILQAHIMKLYPAPFTVSFFYFLIASILTSLIGIVAEKNNPSIWIIHFDITLVCIVVGGIFNPGYYAIHLWAVRNKGPVYLAIFRPLSILIAVIMGAIFLGDSFYLGSLVGGILISLGFYTVMWGKAKEGKTQFLSLSEETPLLDENIDDRI
What are the official names of this protein?
WAT1-related protein At3g28130.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SCP22_ARATH
Sequence: MARTHLLFLLFVLLSLATSSTSTKEQEEDRIKALPGQPKVGFSQFSGYVTVNESHGRSLFYWLTESSSHSPHTKPLLLWLNGGPGCSSIAYGASEEIGPFRISKTGCNLYLNNFSWNTEANLLFLESPVGVGFSYTNTSSDFEESGDERTAQENLIFLISWMSRFPQYRYRDFYIVGESYAGHYVPQLAQKIHEYNNAYKNPVINLKGFMVGNPEMDKNNDRLGTITYWWSHAMISDASYNRILKNCDFTADRFSKECDSAIYVAAADFGDIDQYSIYTPKCVPPQDQTNQTKFEQMMQMHTTKRFLEDQYDPCTENYAEIYYNRPEVQRAMHANHTAIPYKWTACSDSVFNNWNWRDSDNSMLPIYKELIAAGLRIWVYSGDTDSVIPVTATRYSLGKLNLRVKTRWYPWYSGNQVGGRTEVYEGLTFVTVRGAGHEVPFFQPQSALILLRSFLAGNELSRSY
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 22.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_HELPH
Sequence: MLYSLVKKYLFSLDAEDAHEKVCKILRMLSSSPFLCNLIDSQWGYKNPKLENEILGLHFPNPLGLAAGFDKNASMLRALTAFGFGYLEAGTLTNEAQMGNERPRLFRHIEEESLQNAMGFNNYGAVLGARSFKRFAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLSSPNTPNLRDLQNKAFVHELFCMAKEMTHKPLFLKIAPDLETDDMLEIVNSAIEAGAHGIIATNTTIDKSLVFAPKEMGGLSGKCLTKKSREIFKELAKAFFNKTILVSVGGISGAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSVKEAIGADLR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARI2_ARATH
Sequence: MDDNLSGEEEDYYYSSDQESLNGIDNDESVSIPVSSRSNTVKVITKESLLAAQREDLRRVMELLSVKEHHARTLLIHYRWDVEKLFAVLVEKGKDSLFSGAGVTLLENQSCDSSVSGSSSMMSCDICVEDVPGYQLTRMDCGHSFCNNCWTGHFTVKINEGQSKRIICMAHKCNAICDEDVVRALVSKSQPDLAEKFDRFLLESYIEDNKMVKWCPSTPHCGNAIRVEDDELCEVECSCGLQFCFSCSSQAHSPCSCVMWELWRKKCFDESETVNWITVHTKPCPKCHKPVEKNGGCNLVTCLCRQSFCWLCGEATGRDHTWARISGHSCGRFQEDKEKQMERAKRDLKRYMHYHNRYKAHIDSSKLEAKLSNNISKKVSISEKRELQLKDFSWATNGLHRLFRSRRVLSYSYPFAFYMFGDELFKDEMSSEEREIKQNLFEDQQQQLEANVEKLSKFLEEPFDQFADDKVMQIRIQVINLSVAVDTLCENMYECIENDLLGSLQLGIHNITPYRSNGIERASDFYSSQNSKEAVGQSSDCGWTSRLDQALESGKSEDTSCSSGKRARIDESYRNSQTTLLDLNLPAEAIERK
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ARI2, ARIADNE-like protein ARI2, Protein ariadne homolog 2, RING-type E3 ubiquitin transferase ARI2.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: ATG5_PIG
Sequence: MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASISALPWNITVHFKSFPEKDLLHCPSKDVIEAHFMSCVKEADALKHKSRVISDMQRKDHKQLWMGLQNDRFDQFWTINRKLIEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVCPSAVAPEDGEKKSQVMIHGIEPLLETPLQWLSEHLSYPDNFLHISIVPQPTD
What is the function of this protein?
May play an important role in the apoptotic process, possibly within the modified cytoskeleton.  Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.  Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Protein: RS9_HYDCU
Sequence: MATEQYYGTGRRKNSVARVFLRAGSGKMTVNGRDVTEYFARETDLMVINQPLEATENADKFDVTITVTGGGTTGQAGAVRHGISRALVVFNEDNRSTLRQRGLLTRDARKVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LDHC_FUNHE
Sequence: MASVLHKLITPLACSSPEPPRNKVTVVGVGQVGMACAVTILLRELADELALVDVVEDKVKGEMMDLQHGSLFLKTPKIVADKDYSVTSNSRIVVVTAGVRQQEGERRLNLDQRNVNIFKHIIPLIVRHSPDCIIIVVSNPVDVLTYVTWKLSGLPMHRVIGSGTNLDSARFRFLMADKLGIHSSSFNGWILGEHGDTSVPVWSGTNVAGVNLQTLNPNIGTDFDEENWKETHKMVVDSAYEVIKLKGYTNWAIGLSVADLTESLMRNMNRIHPVSTMAKGMYGIGDEVYLSLPCVLNSGGVGSVVNMTLTDEEVAQLQGSASTLWDIQKDLRDI
What are the official names of this protein?
L-lactate dehydrogenase C chain, LDH-C.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMP52_COCIM
Sequence: MATTAIVGGTGLVGSNIVNILLSSPNVAHIDFLARRPPSTPVTKDLIESHPSKFASYISTDPPSSWASHLRSTSPAPEIFFSTLATTRATAGSLAAQRALEHDANVDLARAAKEAGTKVYVLVSSAGADPSSKLPYMKLKGDIEKSILDLNFEKTIILRPGFLSGQREERRIIEGMVGVIGNAAGWLSKPWLKDWWSNDAVEVARASVSAGLAALKGTEPDGQQKVRILAGKDIVRLGRTERKEAS
What are the official names of this protein?
Protein FMP52, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.