PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_SPHAL
Sequence: MTTPLSRIRNFSIIAHIDHGKSTLADRLIQFTGGLTEREMSAQVLDNMDIEKERGITIKAQTVRLSYTAKDGETYQLNLMDTPGHVDFAYEVSRSLAACEGALLVVDAAQGVEAQTLANVYQSIEHDHEIVPVINKIDLPAADVDKVKAEIEDIIGLPADDAVLASAKAGIGIEETLEAIVARIPPPRGDAAAPLVAMLVDSWYDPYLGVVILVRVVDGVLKKGQQIKFMQAGTTHLIDRVGCFTPKRTDLVEIGPGEIGFITAQIKDVAQARVGDTVTDAKKPAAAPLPGFKEVQPVVFCGLFPTDANDFEKLRESIQKLRLNDASFSFEMESSAALGFGFRCGFLGLLHLEIIQERLTREYDLDLITTAPSVVYKLKLSHTKNEAAKEVELHNPADMPDPNRIDEIEEPWIEAVIYVPDEYLGPILKLCQDRRGVQKNLTYVGGRAQITYELPLNEVVFDFYDRLKSISRGYASFDYHQIGHRPGDLVKMSILVNNEPVDALSMIVHRGSAESRGRGMCERLKDLIPRHMFKIPIQAAIGGKVIARETIAALRKDVTAKCYGGDATRKKKLLEKQKEGKKRMREYGNVNIPQEAFIAALRMGDDG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARRA_CHRAT
Sequence: MRIKRREFLKASAAVGAVAVASPTLNAFAQTGTGASAMGEAEGKWIPSTCQGCTTWCPVEFLFRMAVRSKYAATQLSKANNGYCCVRGHLMLQQLYDPDRIKTPMKRTNPVKGRKEDPKICPYHMGMKQWDTIADKIMELRKNNETHKYLLMRGRYSDHNSIFYGDLTKMIGSPNNISHSAICAEVEKMGSMATEGFWGYRDYDLDNMKYLIAWACDPLSSNRQIPNAIRKIQGVMDRGKVVAVDPRMNNTASKAQEWLPIKPSEDGALALAMAHVIITKGLWSKEFVGDFKDGKNKFVAGKTVKEEDFEEKLTNGIVKWWNLEVKDRTPKWAAKVTGIDEATIIRVATEFAQAAPACAIWYGPNMQPRGSYAVMCIHALNGLVGASDSEGGLCTGMGSPSSSYPKIDAYQDDVAKAGAKNKKIDQRGTLKFPAMGSAKPGTGVVTNNVADALLAADPYDIKVAIGYFCNFNFSGTDGARWDKALAKVPFFVHCVPMFSEMTYFADIVLPAALHHTEDWAVIRSKANLHGHTSIQQPVVERMFDVKGVETEITWLLAEKLKAKGFENMYNWLYNEYKDPETGKNPTNSLEFALYATKIRSKKCWDPKENAEYKGDKLNGWADFMEKGIVNSPKFKFRQKWEKGFPTETKKFEFYSETLKKGLLAHAEKNKVTVDQVMEATNYEARGELAFIPHYESPKRHGDVKEFPFSLIDMKSRLNREGRSTNATWYHAFKKCDPGDVNQEDVLQINPADAKKLGINEGDMVKVTSVIGSLTVKARLWEGVRPGCVAKCYGQGHFAMGRVSAKDFGKAVARGANFNDIMPADYDRITGATARNGGFTGVKIEKA
What is the function of this protein?
Component of the arsenate respiratory reductase (Arr) complex, which catalyzes the reduction of arsenate (As(V)) to arsenite (As(III)) (PubMed:9738904).  Can use acetate as the electron donor (PubMed:9738904).  ArrA is the arsenate-binding subunit (By similarity).
What are the official names of this protein?
Arsenate respiratory reductase molybdopterin-containing subunit ArrA, Arsenate respiratory reductase large subunit, ARR large subunit.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FABA_SALTI
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLX2B_DANRE
Sequence: MTAVLDSLGSDMHTNHITSSSFSTVHKSQDSPTLPVSTVTDSSFFSSSQTGHCAGTAYAQLASYSYHPGTVGNVHYSPKAYDLGYASSYGAYGTYGASSSPTPTEPEKEESEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKLWKNGEIPADQQVASGDSPSSSPPPQAGWDFPPNPTQNDGDTVSEQPTGPPNTTAPSFLTNYSWYSSTNAVTHLQPSTLIQPHHSSAMSTGTIF
What are the official names of this protein?
Homeobox protein Dlx2b, DLX-5, Distal-less homeobox protein 2b.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PT1_LACLC
Sequence: MTTMLKGIAASSGVAVAKAYLLVQPDLSFETKTIADTANEEARLDAALATSQSELQLIKDKAVTTLGEEAASVFDAHMMVLADPDMTAQIKAVINDKKVNAESALKEVTDMFIGIFEGMTDNAYMQERAADIKDVTKRVLAHLLGVKLPSPALIDEEVIIVAEDLTPSDTAQLDKKFVKAFVTNIGGRTSHSAIMARTLEIPAVLGTNNITELVSEGQLLAVSGLTGEVILDPSTEQQSEFHKAGDAYAAQKAEWAALKDAETVTADGRHYELAANIGTPKDVEGVNDNGAEAIGLYRTEFLYMDAQDFPTEDDQYEAYKAVLEGMNGKPVVVRTMDIGGDKTLPYFDLPKEMNPFLGWRALRISLSTAGDGMFRTQLRALLRASVHGQLRIMFPMVALVTEFRAAKKIYDEEKSKLIAEGVPVAEGIEVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGEMAGDQTAVPLLMGMGLDEFSMSATSVLQTRSLMKRLDSKKMEELSSKALSECATMEEVIALVEEYTK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTB_ECOBW
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: IRAP_ECO5E
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_FRAT1
Sequence: MIQIKNLKKEYRTNNTSNLVLDNINLEIKQGEIFGIIGHSGAGKSSLLRCLNLLEQPTDGSIFIADENITKKNSKQLREFRKKVAMIFQHFNLLSSRNVFENIALPLEIQGIPKSEIKKRVFELLDLVELPNKANAYPQELSGGQKQKVAIARALALNPLVLLSDEATSALDPTSTKQILALLKILNKELGLTIVLITHEIDVVRKICDRVAIIDKGRIAEMGKTLDVFLNPQAPVTRSFVETSIHTKVPDFIAKKLQDNPYSYDNTYPVVQLTFYGDKGKMPIIAEISRQFNATASIIQANIETIQDQIVGIAICHITGERQGWENALRFLSNQDVNLKVLGYATADNI
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPH_CHLRE
Sequence: MNPIVAATSVVSAGLAVGLAAIGPGMGQGTAAGYAVEGIARQPEAEGKIRGALLLSFAFMESLTIYGLVVALALLFANPFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CAV3_MOUSE
Sequence: MMTEEHTDLEARIIKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPEGTYSFDGVWKVSFTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSNIKVVLRREG
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  May also regulate voltage-gated potassium channels.  Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (PubMed:19380584).  Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (By similarity).
What are the official names of this protein?
Caveolin-3, M-caveolin.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Cell membrane, sarcolemma. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: SSPH2_BACCR
Sequence: MNIQRAKELSVSAEQANVSFQGMPVMIQHVDESNETARIYEVKNPERELTVPVNSLEEI
What are the official names of this protein?
Small, acid-soluble spore protein H 2, SASP H 2.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: AR2BP_XENLA
Sequence: MEDLEEENFSLSVSSPKDAEFDNVVGHLEDIIMDDEFQLLQHGFMDKHYHEFEDTEENKLTYTTIFNEYIGLVEKYIEEQLLQRIPAFDMSAFTSSLQCHREEIAGDIFDILLTFTDFLAFKEMFLDYKAEKEGRTVDLGCGLVVTSLMSSSISSS
What is the function of this protein?
Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity).
Protein: RPN2_HUMAN
Sequence: MAPPGSSTVFLLALTIIASTWALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLSSLGAQVPDAKKACTYIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAVSEDSSVTQIYHAVAALSGFGLPLASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTPVGDVFELNFMNVKFSSGYYDFLVEVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRTAH
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit, RIBIIR, Ribophorin II, RPN-II, Ribophorin-2.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: GP_BUNL8
Sequence: MICILVLITVAAASPVYQRCFQDGAIVKQNPSKEAVTEVCLKDDVSMIKTEARYVRNATGVFSNNVAIRKWLVSDWHDCRPKKIVGGHINVIEVGDDLSLHTESYVCSADCTIGVDKETAQVRLQTDTTNHFEIAGTTVKSGWFKSTTYITLDQTCEHLKVSCGPKSVQFHACFNQHMSCVRFLHRTILPGSIANSICQNIEIIILVTLTLLIFILLSILSKTYICYLLMPIFIPIAYIYGIIYNKSCKKCKLCGLVYHPFTECGTHCVCGARYDTSDRMKLHRASGLCPGYKSLRAARVMCKSKGPASILSIITAVLVLTFVTPINSMVLGESKETFELEDLPDDMLEMASRINSYYLTCILNYAVSWGLVIIGLLIGLLFKKYQHRFLNVYAMYCEECDMYHDKSGLKRHGDFTNKCRQCTCGQYEDAAGLMAHRKTYNCLVQYKAKWMMNFLIIYIFLILIKDSAIVVQAAGTDFTTCLETESINWNCTGPFLNLGNCQKQQKKEPYTNIATQLKGLKAISVLDVPIITGIPDDIAGALRYIEEKEDFHVQLTIEYAMLSKYCDYYTQFSDNSGYSQTTWRVYLRSHDFEACILYPNQHFCRCVKNGEKCSSSNWDFANEMKDYYSGKQTKFDKDLNLALTALHHAFRGTSSAYIATMLSKKSNDDLIAYTNKIKTKFPGNALLKAIIDYIAYMKSLPGMANFKYDEFWDELLYKPNPAKASNLARGKESSYNFKLAISSKSIKTCKNVKDVACLSPRSGAIYASIIACGEPNGPSVYRKPSGGVFQSSTDRSIYCLLDSHCLEEFEAIGQEELDAVKKSKCWEIEYPDVKLIQEGDGTKSCRMKDSGNCNVATNRWPVIQCENDKFYYSELQKDYDKAQDIGHYCLSPGCTTVRYPINPKHISNCNWQVSRSSIAKIDVHNIEDIEQYKKAITQKLQTSLSLFKYAKTKNLPHIKPIYKYITIEGTETAEGIESAYIESEVPALAGTSIGFKINSKEGKHLLDVIAYVKSASYSSVYTKLYSTGPTSGINTKHDELCTGPCPANINHQVGWLTFARERTSSWGCEEFGCLAVSDGCVFGSCQDIIKEELSVYRKETEEVTDVELCLTFSDKTYCTNLNPVTPIITDLFEVQFKTVETYSLPRIVAVQNHEIKIGQINDLGVYSKGCGNVQKVNGTIYGNGVPRFDYLCHLASRKEVIVRKCFDNDYQACKFLQSPASYRLEEDSGTVTIIDYKKILGTIKMKAILGDVKYKTFADSVDITAEGSCTGCINCFENIHCELTLHTTIEASCPIKSSCTVFHDRILVTPNEHKYALKMVCTEKPGNTLTIKVCNTKVEASMALVDAKPIIELAPVDQTAYIREKDERCKTWMCRVRDEGLQVILEPFKNLFGSYIGIFYTFIISIVVLLVIIYVLLPICFKLRDTLRKHEDAYKREMKIR
What is the function of this protein?
Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion.  They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the orthobunyaviruses M polyprotein family.
What are the subcellular locations of this protein?
[Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Glycoprotein C alone is retained in the membrane of the endoplasmic reticulum, but not transported to the Golgi. Coexpression of Glycoprotein C and Glycoprotein N results in efficient transport of Glycoprotein C to the Golgi complex, indicating that their interaction is essential for proper targeting to this organelle, where virion budding occurs (By similarity). SUBCELLULAR LOCATION: [Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Glycoprotein N is retained in the Golgi complex through a Golgi retention signal, which resides in the Glycoprotein N transmembrane region. SUBCELLULAR LOCATION: [Non-structural protein M]: Host Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CSHA_BACAN
Sequence: MTTFRELGLSDSLLQSVESMGFEEATPIQAETIPHALQGKDIIGQAQTGTGKTAAFGLPLLDKVDTHKESVQGIVIAPTRELAIQVGEELYKIGKHKRVRILPIYGGQDINRQIRALKKHPHIIVGTPGRILDHINRKTLRLQNVETVVLDEADEMLNMGFIEDIEAILTDVPETHQTLLFSATMPDPIRRIAERFMTEPQHIKVKAKEVTMPNIQQFYLEVQEKKKFDVLTRLLDIQSPELAIVFGRTKRRVDELSEALNLRGYAAEGIHGDLTQAKRMSVLRKFKEGSIEVLVATDVAARGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKKGIAMLFVTPRESGQLKNIERTTKRKMDRMDAPTLDEALEGQQRLIAEKLQSTIENENLAYYKRIAEEMLEENDSVTVVAAALKMMTKEPDTTPIALTSEPPVVSRGGGSKKRGGNGGGYRDGNRNRSRDGRGGDGRNRDRNRDGRNRDGNRDRNREGSRDGNRGRRGEGQGRPGSSNGRGERKHHSRKPQA
What is the function of this protein?
DEAD-box RNA helicase possibly involved in RNA degradation.  Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT1_STRMU
Sequence: MTEMLKGIAASDGVAVAKAYLLVQPDLTFETVSVTDTQAEEARLDAALEASQNELSLIRQKAVDTLGEEAAAVFDAHLMVLADPEMIGQIKETIRTKEVNAESALKEVTDMFVTLFENMEDNPYMQERAADIRDVAKRVLAHLLGVELPNPATISEESIVIAHDLTPSDTAQLDANYVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITERVKNGDIVAVNGITGQVIINPTEDQIAEFKAAGETYAKQKAEWALLKDAETVTADGKHFELAANIGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNQMFRTQLRALLRASVHGQLRIMFPMVALLNEFRKAKGILEEEKANLKAEGVAVSDDIQVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLVDHVVKAAHAEGKWAGMCGEMAGDQTAVPLLVGIGLDEFSMSATSVLRTRSLMKKLDTDKMQELAQRALTECATMEEVLELEKEYIDFD
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y220B_HAEIN
Sequence: MIFHIFQIDFIYSFLISFIMLKNLDEITSSIIADPQNKDFTERGIFPLFSAPKTARINIVGQAPGLKAEQSRLYWNDKSGDRLREWLGVDYDYFYNSGIFAVLPMDFYYPGYGKSGDLPPRQGFAERWHPMILGNLPNIQLTILIGQYAQKYYLPENKDNVTNTVKNYRQFLPHFMPLVHPSPRNQLWVTKNPWFEEQVIPELQILVKQIINKD
What are the official names of this protein?
Uncharacterized protein HI_0220.2.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily.
Protein: HCAB_ECOHS
Sequence: MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL
What is the function of this protein?
Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively.
What are the official names of this protein?
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase, 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase, CI-dihydrodiol dehydrogenase, Cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, Cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, PP-dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: VPS45_HUMAN
Sequence: MNVVFAVKQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYIIQELRRPKYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSLNILGCCQGRNWDPAQLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVKQVITKEYELFEFRRTEVPPLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESIADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDHSSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLVSAVVEYGGKRVRGSDLFSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKGRLKENLYPYLGPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVTSRSASRR
What is the function of this protein?
May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 45, h-VPS45, hlVps45.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network.
Protein: RSMA_MYCCT
Sequence: MKAKKYYGQNFISDLNLINKIVDVLDQNKDQLIIEIGPGKGALTKELVKRFDKVVVIEIDQDMVEILKTKFNHSNLEIIQADVLEIDLKQLISKYDYKNISIISNTPYYITSEILFKTLQISDLLTKAVFMLQKEVALRICSNKNENNYNNLSIACQFYSQRNFEFVVNKKMFYPIPKVDSAIISLTFNNIYKKQINDDKKFIEFVRTLFNNKRKTILNNLNNIIQNKNKALEYLKMLNISSNLRPEQLDIDEYIKLFNLIYISNF
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K0087_HUMAN
Sequence: MEAWESSQPLLRCEIPCPLPGTDRDGSVSLPGEAASCDLDTLEPEHGNRRVSGNPISVCWAYKVTKVKCWSVRERGGRHIGGPRSTLKHPAHHGMGKNLATSLPTAASLGLGKGQLLVSIRFMDTTKKRGQSETFNIC
What are the official names of this protein?
Uncharacterized protein KIAA0087.
Protein: RF1_PELPB
Sequence: MLDKLQSIKEKHLDLEQLLSDPNAAADQVRFRKLNKEYSDLREIVQAYDLYAATKTELDESRQLLKSESDAEMKELVQAEISELQKKLPELEQQLKILLLPKEEADSRNVIIEIRAGTGGEEAALFAADLTRMYQRYAEHQGWQCETLHFNESSVPGGFREITLSVNGHDVYGTMKYESGVHRVQRVPDTETQGRIHTSAVSVAVLPEAEEVDVEIRREDLRFDTYRSGGKGGQNVNKVETAVRITHMPTGIVSACQEQRSQLQNKERAMQMLRTKLYDIQLAEQQQQRADLRRSMVTTGDRSAKIRTYNYPQSRVTDHRIAFTSHALPQILQGDLQDIINALKMHDQAARLQAELV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y499_GEOSW
Sequence: MGIKYSSKINKIRTFALSLIFVGFIVMYIGIFFRTSPFVMTLFMILGLLFIIASTVVYFWIGTLSTRAVKVVCPSCGKITKMLGKVDLCMFCNEPLTLDPELEGKEFDEKYNRKKRKS
What are the official names of this protein?
UPF0295 protein GWCH70_0499.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.