PharMolix/UniProtQA huggingface dataset:
Protein: GLMM_AFIC5
Sequence: MARKYFGTDGIRGRANGVITPELALKVGQAAGLVFQRGEYRHRVVIGKDTRLSGYMIETAMVAGFTSVGMDVLLLGPIPTPAVAMLTKSMRADLGVMISASHNPFADNGIKLFGPSGYKLSDEVELQIEELMDENIDRRLAQSTQLGRARRIDGVHDRYIEFAKRTLPRELSLEGLRVVVDCANGAAYKVVPEALWELGADVIAIGAEPDGMNINKECGSTSPDALAHKVREMRADIGIALDGDADRVLMIDERGHLIDGDQLLAVIAQSWKEDGRLAKPGIVTTVMSNLGLERFLAGEGLSMVRTPVGDRYVLEQMMAQGYNLGGEPSGHIIMSDFTTTGDGFVAALQVLAVVQKLGRPVSEVCHRFEPLPQILKNVRYRSGKPLENPKVQSTIADAEKKLNGCGRLLVRSSGTEPVIRVMGEGDDRDRVEEAVDMIVAALSIGVAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CYSG_HAHCH
Sequence: MSTQLQTWDFLPISMNLQGRECLVVGDTEQAVRKTDLLLRAGAKVRLLGDPHAKALKESADALNAITVIPDPFHPDLLQLCAVVVAASDSAMLNQQVAQAAQARGIPVNVVEQPELSSFIFPSIIDRHPVLVSVTSSGGAPVLTRLLRNRLESLIPHGFGRLADLAMEFRDKVRSRFGHINQRRRFWESVLEGVVSDLVFCGRTDKARAMLDDMLSGEQADAIKDTGEVYLVGAGPGDPDLLTFRALRLMRQADVVLYDRLVSPQILDLVRRDAKRINVGKARSNHTLPQQEINAMLVELAKEGKRVLRLKGGDPFIFGRGGEEIDQLADAGVPFQVVPGITAASGCAAYSGIPLTHRDHSQSVRFVTGHLKSDTCDLPWHEFVQDNQTLVFYMGLVGLPIISRELIAHGMKPSTPIALVSRGTLPDQQVLVGELGNIAKKVEEQQIPGPTIIIIGDVVTLRDRLRWMD
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: SYI_SHEB2
Sequence: MSDYKFTLNLPETEFPMRGNLANREPEMLERWTKDGLYQQIRDSRIGRTPFILHDGPPYANGSIHIGHSVNKILKDIIIKSKTMSGFDAPYVPGWDCHGLPIELKVEQKVGKPGQKISAAEFREECRKYAAEQVNGQREDFIRLGVLGDWQNPYLTMDFSTEANIVRSLSKVIESGHLHKGVKPVHWCTDCGSALAEAEVEYEDKTSPAIDVAFVAADSKAVAAKFGVSDYSHPVSMVIWTTTPWTLPANRALSLSPELDYSLVEFEKDGVTQALILAEVLVESCLTRYNVESHTVLGSAKGAAFELVRFNHPFLDFDVPAILGDHVTTDAGTGIVHTAPGHGQDDFVVGQKYGLEVANPVGDNGVYKPDTEYFAGQHVFKANDNVVALLREKSALLNHVAYRHSYPHCWRHKTPIIFRATPQWFISMDNHGLRTQALKEIEQTQWIPDWGQSRIEKMVENRPDWCISRQRTWGVPITLFVNRETEELHPDSVSLMERVASRIEQQGIQAWWDLDAAELLGDEAEQYRKVTDTLDVWFDSGSTFSSVVAARPEFHGHGVDLYLEGSDQHRGWFMSSLMISTAMNGKAPYKQVLTHGFTVDGKGRKMSKSIGNVIAPQTVTNKLGADILRLWVAATDYSGEMTVSDEILNRSADAYRRIRNTARFLLANLNGFEPAKDLVAVEDMVALDRWVVRRAAALQQEIIEAYEQYNFHIVTQKLMQFCSVELGSFYLDIIKDRQYTAKQEGHARRSCQSALYLISEAMVRWIAPILSFTADEVWQLLPGERDAYVFTQEWYQGLKSVTLATDLSDDYWQQLLTVRNEVNKVIEQARRDKRIGGSLEAEVTLFADAALTEQLTHIGDELRFVLLTSEAKVLPLADATSEAVETELASLKLLVASSTAEKCERCWHHREEVGTIEAHPTLCTRCVTNIEGDGEVRLFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SALPA
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MCC03_ARATH
Sequence: MGNHQAVKKLWVINNFSFLDSDRVYSDIFVVGGCKWCLLALPEGNNNYIYDYFSLYLCVPDSEYLPSGWRRRAKVSFTMVNQVTGELSQQQEGVYWFDEKNTTQGFGSMFRLLVFQSSYKGFLVNGEVDIVAEVDVVEVIGKLDVSEESESIDSNGFDVLASQVESVNSLFGKYPCFASKLCPKTPRLKKNVVQSLNEILCKSTKELSNGDLAEAYSALRFVTKAGFKLDWLEKKLKETGKSRLQEIEEDLKDLKVKCADMDALLEFLR
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At2g01790, RTM3-like protein At2g01790.
Protein: FUT6_ARATH
Sequence: MYHIFQISSEVFRAFGLKMKILLTLVFSGLLIWSVVLVSFSNDFNNQLLVATSNVSRESETPRDRLIGGLLTADFDEGSCLSRYQQSLLYRKASPYKPSEYLVSKLRSYEKLHKRCGPGTDAYKKATEILGHDDENYASKSVGECRYIVWVAVYGLGNRILTLASVFLYALLTERVVLVDQSKDISDLFCEPFPGTSWLLPLEFPLMKQIDGYNKGYSRCYGTMLNNQAINSTLIPPHLYLHILHDSRDNDKMFFCQKDQSLVDKVPWLIVKANVYFVPSLWLNPTFQTELMKLFPQKEAVFHHLARYLFHPTNQVWGLITRSYNAYLSRADETLGIQIRVFSDRAGYFQHVMDQVVACTRRENLLPEPAAQEEPKVNISRSQKLKAVLVTSLYPEYSETLKNMYWERPSSTGEIIEVYQPSGERVQQTDKKLHDQKALAEMYLLSLTDKIVTSARSTFGYVAHSLGGLKPWLLYQPTGPTAPDPPCIQSTSMDPCHLTPPSHGCEPEWGTNSGKVVPFVRHCEDRGNDGLKLFDEL
What is the function of this protein?
May be involved in cell wall biosynthesis.  May act as a fucosyltransferase.
What are the official names of this protein?
Fucosyltransferase 6, AtFUT6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 37 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: RS15_SHIDS
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SSRP_NEOSM
Sequence: MKVIAINKKARFDYSLIDEFEAGIVLLGTEVKALKYHSASLNEAFVAFRRFELWLNNMHVPPYKPASRFNHVPTRSRKLLVHKRQLNKISGAVRTKGLTLVPLSIYVNENGLIKVKFALAKGKKKHDKRQDIKDRDWARKQARQDFS
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SSRP_OCEIH
Sequence: MPKGNGKVIAQNKKASHDYFIEDTYEAGIVLHGTEIKSIRNGRVNIKDSHARIDRKGEVQLINLHIAEYEQGNRYNHDPTRSRKLLLHRKEIDKLIGLTQQQGYALVPLKIYLKNGFAKVLIGLGKGKKKYDKREDLKQKQMKRDVDRAIKDHMR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FETP_ALBFT
Sequence: MARTVNCIKLGKEAEGLDFPPYPGELGKRIWESVSKQAWADWLKHQTMLVNENRLNLADARARQYLARQMENHFFGGGADAAQGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: Y2235_MYCBO
Sequence: MYDSLDFDALEAAGIANPRERAGLLTYLDELGFTVEEMVQAERRGRLFGLAGDVLLWSGPPIYTLATAADELGLSADDVARAWSLLGLTVAGPDVPTLSQADVDALATWVALKALVGEDGAFGLLRVLGTAMARLAEAESTMIRAGSPNIQMTHTHDELATARAYRAAAEFVPRIGALIDTVHRHHLASARTYFEGVIGDTSASVTCGIGFADLSSFTALTQALTPAQLQDLLTEFDAAVTDVVHADGGRLVKFIGDAVMWVSSSPERLVRAAVDLVDHPGARAAELQVRAGLAYGTVLALNGDYFGNPVNLAARLVAAAAPGQILAAAQLRDMLPDWPALAHGPLTLKGFDAPVMAFELHDNPRARDADTPSPAASD
What are the official names of this protein?
Uncharacterized protein Mb2235.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein: SYA_BURO1
Sequence: MKAAEIREKFLKFFESKGHTIVRSSSLVPGNDPTLMFTNSGMVQFKDVFLGTDPRPYSRATTAQRSVRAGGKHNDLENVGYTARHHAFFEMLGNFSFGDYFKHDAIKFAWELLTTVYQLPKDKLWVTVYQEDDEAYDIWAKEVGVPTERIIRIGDNKGARYASDNFWTMGDTGPCGPCTEIFYDHGPDVWGGPPGSPEEDGDRYIEIWNLVFMQFNRDAQGNMTRLPKQSVDTGMGLERLAAVLQHVHSNYEIDLFQNLIKAAARVTEISDLTNNSLKVIADHIRACSFLIVDGVIPGNEGRGYVLRRIVRRAIRHGYKLGRKGAFFHKLVADLVAEMGTAYPELKEAEQRVTDVLRQEEERFFETIEHGMSILEAALAEVEAKGGKVLDGELAFKLHDTYGFPLDLTADVCRERGMTVDEPAFDDAMARQREQARAAGKFKATQGLEYSGAKTTFHGYEEIAFDDAKVVALYVDGSAVNEVKAGQDAVVVLDHTPFYAESGGQVGDQGVLANAATRFAVADTLKVQADVIGHHGTLEQGTLKVGDVLRAEIDAQRRARTQRNHSATHLMHKALREVLGAHVQQKGSLVDADKTRFDFAHNAPMTDDEIRRVEQIVNNEILANAPGIVRVMPYDEAVKGGAMALFGEKYGDEVRVLDLGFSRELCGGTHVHRTGDIGLFKIVVEGGVAAGIRRVEAITGDNAVRYVQELDARVNEAAAALKAQPSELTQRIAQVQEQVKSLEKELGALKSKLASSQGDELAQQAVEVAGVYVLAATLDGADAKTLRETVDKLKDKLKSAAIVLAAVEGGKVSLIAGVTPDASKKVKAGELVNFVAQQVGGKGGGRPDMAQAGGTEPANLPGALAGVKGWVEERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: RNS1G_RATRT
Sequence: MGLEKSFLLFSLLVLVLGWVQPSLGVESRETQTQKFQRQHMDEEGHFPSSPTYCNQMMKSRGMTSGSCKPMNTFVHEPLETVQAICSQGQVTCKNGKRNCHKSSSTLRITDCRLKGSSKYPKCDYTTTDSQKHIIIACDVVHLDATV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic gamma-type, RNase 1 gamma.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIFH_SYNJB
Sequence: MRQIAFYGKGGIGKSTTCQNTVAGMAELGQRIMIVGCDPKADSTRLMLHCKAQTTVLHLAAERGSVEDVELEEVVLTGYRGVRCVESGGPEPGVGCAGRGIITAINFLEENGAYEDLDFVCYDVLGDVVCGGFAMPIREGKAQEIYIVCSGEMMAMYAANNIARGVLKYAYSGGVRLGGLICNSRKVDREIELIEALAEKLNTKMLHFIPRDNVVQHAELRRMTVIEYSPDCNQADEYRALAKKIINNTDLRIPTPISMDELEQLLIEFGVLDDDQKIAHLIGKTEKELAPV
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ACTNB_DICDI
Sequence: MEHSTPLNEEIVHKKNDENWVIAQKKVFTNWCNIFLNQRSQKIEDLETDLYDGILLGSLLEILSGKNVILSKCKQLKTRLHYINNLNFSLKFIGDEGLRLVGVASEDITDGNLKLILGLVWTLILRYQIQSMQNSKSSQQNLHSSTKPSELMLNWVKSQISDYGHHIKDLTTSFQNGLLFCALVHKLVPEKLDYKSLSESDSLGNLTLAFEVANKELGIPSILDPHDIITTPDELSILTYISLFPKVYQQTLEPLNNNNNISPSLSSSSSSLLNTPNKRNSIQLSKSTSFEQQNQQQQQQNLLSPNSYRNSISFSKSPSFEGSQSTGSSRSISPISSPIKNSTTGNSNLSKSTSFEKIEASNTTNNNTIIIAEESRVIEKIVEKIIEVEKIVEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTNLQDQLTEQQQQYQEKSLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMNDLTDIPTQDIKEKDEIIANLKIESEKNLKCFQDDFNALQSRYSLTIEQTSQLQDRIKQLINELQERDDKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQDIKEKEFQFEKQQLLSQIDSITTNIQEYQDKFNNLQQEFNTQQTLNQQETHRLTQQLYQINTDYNEKQTQLQSEIKDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQDEKINNLLLEIKEKDCLIERINQQLLENIDLNSKYQQLLLEFENFKLNSSKEKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTIIELSELKEQKELNDSKLIEKEKQLQQLQQEFDQLNEKNQKDHQDQLELLEKQLKQLQQEYDQLNETNQSIENQLNQQNLINKENLNEKEQELLKLQNQLNQQIEKIQFDQQEFSKQNSINIELVNEKNEKLIQLQQDYDQLKQQNRSNDEKDENDLIEKENQLKSIQNELNQLIEKNESDHKEQQLKQQSIENDLIEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNQFDQKEQQLKQQSIENDLFEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQKEQQLKQQSIENDLIEKENQIQQLQLQLNEQRQLQSEVSIDNDKILELEKQLKQCQSDLLKLNDEKQQQDKQLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQNLNQLNDENQEKVKQFSEKDEKLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLNQLNDDQIKKNEKLKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQLNQQQQSNEIIQQLKDQLLKQQQQEQQENNNEKEIERLIQEIEQLKQQQEIDQSELSNKEIKIQTTQQEFDQLSHNRSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQSTLSNNQLDQLLKEKLKPLELDSNEKQKTIDDLLSNISNLQISLQNDKDLISERNNSIKTLESRITQQLSLLDEKDNLIKDLQQQKQQQQQPPTASSSPSSSPSLLSSTPTPKPQRPNQIEIDRLVNEIVNRNQDLIRKNKTKFYKLENGDYIVNSIIYRLSLDDDNDSDLIAQEYENGNSTTFEKSLRIFPSKNTRPIFDWRALFFIGAAVLAISTLFSSSRPIKYEKPT
What is the function of this protein?
May function as linker between cellular membranes and the actin cytoskeleton.  Required for normal development of fruiting bodies.
What are the official names of this protein?
Interaptin, Actin-binding protein D, Alpha-actinin B.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass type IV membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus, Golgi stack membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Note=The largest part of the protein is cytoplasmic, while its C-terminal part is associated either with the nuclear envelope, the Golgi membrane or the endoplasmic reticulum membrane.
Protein: SYP_STAAM
Sequence: MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLPLATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGRQFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGEDTIVYSKESDYAANIEKAEVVYEPNHKHSTVQPLEKIETPNVKTAQELADFLGRPVDEIVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLGPVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDEYGDFRFILEGEKLSDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQPLIMGCYGIGISRTLSAIVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQERAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLMTVITNKYDNLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT134_MOUSE
Sequence: MGDHLEKSQHALLNEGDENEMEIFGYRTQGCRKALCLIGSIFSLGMLPLVFYWRPAWRVWANCVPCSLQEADVVLLKTTDEFKIYSWKKVIWISLSALSSTSGLTPDHPLITDEGYIINRAIRKPDLKVRYIKVQKIRYVWNNLEGQFQKIGSLEDWLSSAKIHQKFGLGLTSEEQEIRRLICGPNAIDVEITPIWKLLIKEVLNPFYIFQLFSVCLWFSEDYKEYALAIILMSVISIALTVYDLRQQSVKLHHLVESHNSITVSVYERKAGAQDLESRLLVPGDLLILTGSRVQMPCDAILIDGSCVVDEGMLTGESIPVTKTPLSQTASSVPWKMQSEADPRRHVLFCGTEVIQAKAAGSGAVRAVVLQTGFNTAKGDLVRSILYPKPMNFKLYRDAIRFLLCLVGTATIGMVYTLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTGIIYAQRRLKKKGIFCISPQRINVCGQLNLVCFDKTGTLTRGGLDPWGVVPCDQNGFQAVHSFASGKALPQGPLCAAMASCHSLILLDGTIQGDPLDLKMFEATKWEMTASGDDLHIKEMLAHTIVVKPTDMVGQVPAEGLAIVHQFPFSSALQRMTVIVQEMGGGRLAFMKGAPERVASFCQPDTVPTSFISELQIYTTQGFRVIALAYKKLEMDCPTTALMREKVESDLVFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSEGQKVILVEANEATGSSSASISWKLVEEKKPGPFGSQDTYINIREEVPENGRDRSYHFALSGKSFHVISQYFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFCMFKYMALYSMIQYVGVLLLYWKTNSLSNYQFLFQDLAITTLIGVTMNLNGANPKLVPFRPAGRLISPPLLLSVVLNILLSLAMHIVGFILVQKQPWYIMDYHSVCPVRNESASALAASPSVPEKTRSNSTFASFENTTIWFLGTINCIFVALVFSKGKPFRQPTYTNYIFVLVLILQMGVCLFILFADIPEMHRRLDLLCTPVLWRVYILIMISSNFVVSLAVEKAIIENRALWIAVKRCFGYQSKSQYRIWQRNLANDSSWPPLNQTSYSDMQGVSYSNPVFESNEEQL
What are the official names of this protein?
Probable cation-transporting ATPase 13A4, P5-ATPase isoform 4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
Protein: LYSZ_SULIN
Sequence: MIVVKIGGRVVKNSLDKVILDIANINDKVILVHGGGDIVTDYTKRLGIEPVFVTSPEGIRSRYTTKEELEVYIMAMSLINKMITSKLCSLGKNAIGITGADGGLLLAERKKRIIVIDERGKKRIIEGGYTGKVKEVRSEVINHLMKLFDIIVVSPLALDVEESTPLNIDGDQAAFAISKAVKVNVLVILSDVEGVLVEGKVVDRLTPEEAKELSKKIGPGMNRKLLMAAESVENGVNKVIIGSGVKDRPVSSALELNGTVIVNG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
[LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA2_STRPM
Sequence: MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_SFV1
Sequence: MAAIEGDLDVQALANLFNDLGINRNPRHREVIALRMTGGWWGPATRYNLVSLLLQDDQGQPLPQPRWRAEGRAANPAVMFTLEAPWQDLRLAFDNIDVGEGTLRFGPLANGNYIPGDEFSLEFLPPAMQEITQMQRDELEEVLDVVGQITMQMNDLIGMQDAQIRGLEGQLRGLRGNLPVAGTPPPPPPSLDLQPAAASSPYVAPAPSAPAASAAAADLGWFAGGPGPGSLDPRLARVAYNPFLPGPSDGSGAAPAQPSAPPVASPLPSLLPAQPMQPVIQYVHPPPINPAQQVIPIQHIRAVTGNAPSNPREIPMWIGRNASAIEGVFPIPTSDIRSRVINALLGRQLGLNLDPQHCITWASAIATLYVRTHGSYPLHQLAEVLRRVSNSEGAAAAWQLGMMLTNQDYNLVWGMVRPLLPGQAVVTAMQHRLDQEVSDAARIVSFVNHLNAVYELLGLNARGQNLRVSTGGQTTARTSAGRGARGRRSQQGTPGRQSSGQAPPQGRRSSQGQQPRQSESGDQNNQRQLQGGNNRGGYNLRPRTYQPQRYGGGRGRRWNDQTARADNQQRSQSQQPQSEARGEQSRTSGAGREQGGRGNQNRNQRSAGENTDRSVNTVTATSASISASGQNGSSTTPPASGSGNQGN
What is the function of this protein?
Involved in capsid formation and genome binding.  Shortly after infection, interaction between incoming particle-associated Gag proteins and host dynein allows centrosomal targeting of the viral genome (associated to Gag), prior to nucleus translocation and integration into host genome (By similarity).
What are the official names of this protein?
Gag polyprotein, Pr71Gag.
What are the subcellular locations of this protein?
[Gag protein]: Virion. Host nucleus. Host cytoplasm. Note=Gag protein is nuclear at initial phase, cytoplasmic at assembly. Shortly after infection, Gag protein is targeted to centrosomes. It is then actively transported into the nucleus thanks to its nuclear localization signal. In the late phases of infection, Gag proteins assemble in the cytoplasm to form the virion's capsids (By similarity). SUBCELLULAR LOCATION: [p3]: Virion.
Protein: KAD_KOSOT
Sequence: MNIILLGPPGAGKGTQAKKIAMRYGIPHISTGDMLREAVAAGTELGKKVKEIIEKGLLVPDDLMVAIVEDRLKKPDSAKGFILDGFPRTVQQAESLSGILGNLGKELDAVILIDAPEEVVVERISSRRVCPSCGKVYNLLTIKPKNDMLCDDCNIGLIQREDDKPATVRERYRVYMEKTAPVINYYSEHGSLITIDGSLDIEAVTEEIFKNLENL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_NATTJ
Sequence: MHIDIMTLFPEMFHGVLESSIIGRALAREMITVNLIDIREFSTNKHRKVDDYPYGGGAGMVMKPEPIFYAMDELKKSPSFNVNQKTVFVTPQGNPYSQEKAKELSSLNRLTILCGHYEGVDERVRQHLVDEEISVGDYVLTGGELPAMVILDSVTRLVPGVLGDESSAKTDSFNNYLLEHPQYTRPAIFRGLEVPEILMSGDHKRIATWKTKESLKRTLSRRPDLLDKKSLTEEEYKLMREILKESPNKELDLDRL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.