PharMolix/UniProtQA huggingface dataset:
Protein: TU3A_UNEBI
Sequence: DCCPCPAGAVRCRFACC
What is the function of this protein?
Elicits excitatory activity in two subsets of the mouse dorsal root ganglion neurons; the medium diameter isolectin B4-expressing neurons and the small diameter CGRP-expressing neurons.  Displays low inhibition of the human alpha-9-alpha-10 nAChR (IC(50)=10. 2 uM).  In vivo, intracranial injection into mice causes strong tremors and impaired locomotion for around 3 hours after administration.
What are the official names of this protein?
Turripeptide ubi3a.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS2_TERTT
Sequence: MSDVLAELDKVLAQRKNAGDPESSYVAKLHHKGLNKILEKVGEECTETILAAKDAQHDSDTQHLIYETADLWFHSLVMLSHLGLSAEDVLNELARRFDLSGLEEKARRQS
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASF5_RAT
Sequence: MASPAIGQRPYPLLLDPEPPRYLQSLGGTEPPPPARPRRCIPTALISASGASEGRGSRRNARGDPEPTPRDCRHARPVRPGLQQRLRRRPGSHRPRDVRSIFEQPQDPRVLAERGEGHRFAELALRGGPGWCDLCGREVLRQALRCANCKFTCHPECRSLIQLDCRQKEGPALDRQSPESTLTPTFNKNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGDVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG
What is the function of this protein?
Potential tumor suppressor.  Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation.  Stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1.  Together with RAP1A may participate in regulation of microtubule growth.  The association with activated RAP1A is required for directional movement of endothelial cells during wound healing.  May be involved in regulation of Ras apoptotic function.  The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis (By similarity).
What are the official names of this protein?
Ras association domain-containing protein 5, Maxp1, New ras effector 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Mainly located in the perinuclear region of unstimulated primary T-cells; upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A (By similarity).
Protein: MARH5_XENLA
Sequence: MSESNSVSVQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPNLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVVLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRVPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSTVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILDSQEPEPEEV
What is the function of this protein?
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission.  May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF5, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, MARCH-V, RING-type E3 ubiquitin transferase MARCHF5.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CFA36_CAEEL
Sequence: MLRRFSKKNKNPEGGSDDASRKQKKLLSKFLEFITSSIWSIPIASFIESQSVVFDRQQMETDVYIMIHKEYSQLIDTLIECFCEDVGTTPTELVAAIQLFNQKDVSQQYKVALEPLLAAQNFNVFVPMMMRKNIELQLQALQMIEFMCGLIPSVLQLEDGETLRNMKKLSPEETERYVLISVLRHSKDEYDSMQKGSEELEMMAQNSRIQREALEQEIRKEEILLQQALDEGARAQNQNQNQGTSSTQTDGVNAPLRSVAAMMAATFAIDTATSTDDVTYKFLDQSTGTMTSSTGVSVGTLTNTGVSSGTMTSGVDTGTDADGTVGRPKSAKRVGSAVGKRSVSKGTPSEDAKKSSGSSSPDEAEKSKRERPGTSVKKAIGIVAANSEMSSNGTQMDVPVDEEGTKKRPGTTSKKSIATVTASPEMSSKTTQMEPEQDGEGKKRPETSKGANERKYSNAGLEDIVGPKSSPHEEKKSSHPSSRKGSKATDENAPATRPPSRKAAGGSHEPRAKTPNQKNKDERPTTRRSSVDKNAPKRNDSVPRERKSSVSHDESKPPKPIGPLRGNKYDGDVVLGRAESPGIDHGPRRKNLNDVNSHLVDTNRLNSSDVRVRAQYLREQRDKLLQMKNAERIKQMTDIQQNASLERPKTAARAREILDKDKKEAVAIRKEISDKLKTQILTLHH
What are the official names of this protein?
Cilia- and flagella-associated protein 36, Coiled-coil domain-containing protein 104.
What is the protein family that this protein belongs to?
Belongs to the CFAP36 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes to the base of the cilium.
Protein: NORV_ECOLC
Sequence: MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALKLCREHGREIARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFEELASEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_PSINU
Sequence: MKEIESFLVYSSSILPECILIFSSIGILSIDLLSLPNEGDTFWSYSISLAALAISIIILLLQWNKEPVLTFSETFQISRFNDIFRFFLLICSFLCIPLSVDYIRCTKMPVTEFLLFVLTATLGGMFLCGANDLISIFVASECLALSSYLLSGYTKRDVRSNEAMMKYLLMGGASSSILVYGFSLPYGLSGGEIQLRGMVNGLINMQMYNSAGVSIAMIFILVGIGFKLSLVPFHQWTPDVYEGSPTPVVAFFSVTSKVAALALATRLFHILFSSLSNEWHLPLEILAILSMILGNLIAVTQTSMKRMLAYSSISQIGYILIGIIAGDSDNGYASMITYMLIYIFMNLGTFACITSFGLRTGTDNIRDYAGLYRKDPILTLSLVLCLLSLGGIPPLAGFFGKLYLFWCGWKAGLYFLVSIALFTSVISIYYYSRIIKLLFTERNKRITIYMQDYKGSPYFLIPNNSIGITMILCTIASTVPGILINPIIAIAQNTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SELO_NOSS1
Sequence: MTLAETFNTENHGNPLITLNYEPALESLGNDYYDEVTAAEFPQLTLRWRNDAILPRLGLNPQIVTDEDFITAFGLFQGRKPLLALRYHGYQFGEYNPNLGDGRGFLYGQVRGTDGELYDFGTKGSGRTPYSRGGDGMLTLKGGVREVLAAEALHQLGVRTSRCLTMIETGLGLWRGDEPSPTRSSVMVRMNKSHIRFGTFERLHYFQRSDLIKKLLDHVIEHYYRHLAHESDKYALFYAELVKRVAELVAQWMAAGFCHAVLNTDNMSITGESFDYGPYAFIPTYNPYFTAAYFDYYGRYCYIQQPSICQWNLEMLQVPLRAVIDKADMEAGLAKFSEYCHAEYNSLMLKKLGFEELKTPEAEELLSLTLKFLQESQVGYHQFFYEMARTFSIKWRDEPGLVLSGSDIVPPSGTDANFDNWCVLYHKILNNFDYEQVKIIAQNLTHYNPKTSLLRPTIEEAWEPIVQEDNWQPFYDLVKSIQSRG
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: 102R_IIV3
Sequence: MTLEDECKQLMVCRDEIKKLKLKEKEAKNRILTYLKNHNQYGVIFKHNKKQISITVETTPVKKNPSLKEKQTKIQDILSGVGVANPDATTQEIIDGLKTTTITDTSNQKDVLKLKMGKRAG
What are the official names of this protein?
Uncharacterized protein 102R.
Protein: NU1C_BARVE
Sequence: MIIYATAVQTINSFVRLESLKEVYGLIWIFVPIFSLILGIITGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKENLRPSRGNPPLFSIGPSIAVISILLSYSVIPFSNHLVLADLNIGIFLWIAISSIAPIGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSLSTVDIVEAQSKYGFWGWNLWRQPIGFIIFLISSLAECERLPFDLPEAEEELIAGYQTEYSGIKFGLFYVASYLNLLISSLFVTVLYLGGWNISIPYISILELFQRDQIFGTTIGIFITLAKTYLFLFISIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSFQLFSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MOXD1_CHICK
Sequence: MRPLRPWALLLGALLGAAAAAARRYPHVAVLDGAAAYRLLWGRRGSALAFRLEVRTRGYVGFGLSAGGGMASADIVVGGVEGGRPYLQDYHTDENRVLKKDPQQDYHLEYAMENSTHTILAFSRELYTCDPNDKSITESTVRVIWAYHHKDLGEAGQNYHGSTRGTKSLRLLNPEKAEVSPASLSYFDLTNKDVPVPDKDTTYWCQMFKIPVQHEKHHVTKVEPLIQKDHENLVHHILLYQCSSNLNDSVLDYGHECYHPNMPDSFFTCETVIFAWAIGGEGFTYPPHVGLSIGTAADPQFVLMEVHYDNPTYTEGLIDNSGLRLFYTPVLRKYDAGVIEAGLWVSLFHNIPPGMPEFVSEGHCTLECLEEALGAERPSGIHVFAVLLHAHLAGRAIRMRHFRNGEEQKLLAYDEEFDFNFQEFQYLEEERTIMPGDNLITECHYSTTDRIRMTWGGLSTRNEMCLSYLLYYPRINLTRCASIPDIMEQLQFIGVKEIYRPVRTWPFIIKSPKQYKNLSFMDAMNKFKWSKSEGLSYNELVLKLPMNVRCSKTDNAEWSFQGMTAFPPEVERPYKTEPVICSSSSCLPCSLSLTLLFVVYVASSTIGNFGPVVQ
What are the official names of this protein?
DBH-like monooxygenase protein 1, DBH-related protein, Monooxygenase X.
What is the protein family that this protein belongs to?
Belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TX18A_MYRGU
Sequence: MKLSTLLVAFVLLVITVILSTPSTNAKALAESNALAVAVSEAEPWLGALFSFIRFIAPYVIRAVRVLIQVVSKVVKPAKVAMKYAKKIATNVAKDVAKDMATDIAIDTITGGDE
What is the function of this protein?
May have antimicrobial properties, like most ant linear peptides.
What are the official names of this protein?
U-myrmeciitoxin(01)-Mg8a, MIITX(01)-Mg8a, U-MIITX(01)-Mg8a.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_PSEPF
Sequence: MQTVAVIDYGMGNLHSVAKALEHVGAGKVLITSDAAVIREADRVVFPGVGAIRDCMAEIRRLGFDSLVREVSQDRPFLGICVGMQALLDSSEENDGVDCIGLFPGAVKFFGKDLHEDGEHLKVPHMGWNEVKQAVDHPLWHNIPDLARFYFVHSYYIAAGNPRQVVGSGHYGVDFAAALAEGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAST_HALS3
Sequence: MSDIDRGLFERVLPARIRGSYAAKFNVLLLVVVIIVAAAGGYIHLQTQSTVGENTERRVSGIAEQQAATLHDWLTQKESTTTFLASNIGGDAVRTSDVKPQLERQLATLQQDVRAIHVVSTSQDTVVASTDDARSGTTLQAGDAPWLSTIEDGTTDVSVSDPYEVDDSPVVAMTAPTDKPGWVLVMTMSLAQHSQSFNSPIATGDVKVVNGDGVITLDNRNRALLEQYTDTAGNVPAAVATARSGQTVYNTEPERTGMDDGRYATAYTPVAGTDWVLTYHVPRGQAYALQSEVTQNLAGLVVVALVGLLLVGLTVGRRTSSALDELAGVAAAIADGDLDTTIPDTDRTDELGQLVGAFGEMQTYLTTAASQADALADQNFDADVLDEDLPGAFGASLSQMHTRLEALITDLDEAREDAEQTRKDAEEARAASERLNERLERRAAEYSDEMAAAAAGDLTRRLDEDVDSEPMQDIAEAFNDMMGDVEATLAQVRSIADAVDAASTDVSTSAAEIRSASDQVSESVQDISADADQQRDRLGTVGDEVTSLSATVEEIAASADDVAETVNQAATESERGQELGEDAVAELERIEATADSAVERVTALEEAVDAIGDVTGVITDIAEQTNMLALNANIEAARADKSGDGFAVVADEVKDLADEVKESATEIETLVDDVQADVADTVADMSELGDRVDAGSETIEAALAALDDIGDQVEAANGSVQSISDATDEQAASTEEVVTMIDEVTDLSDRTATESQQVSAAAEEQAASVSEVAGRADDLDDQVSTLNDLLDQFDARAASADTDEN
What is the function of this protein?
Mediates chemotaxis towards five attractant amino acids (leucine, isoleucine, valine, methionine and cysteine).  Probably transduces the signal from the substrate-binding protein BasB to the histidine kinase CheA.
What are the official names of this protein?
Transducer protein BasT, Branched chain and sulfur-containing amino acids transducer protein.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXJ_STUS1
Sequence: MTEANRILLGVNVDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLMMKDALQTRMNFEMGVTEAMLAFAEQLRPEHVCLVPETRQELTTEGGLDVAGQEARIREAVERLRGCGAEVSLFIDADPRQIEAAARVGAPAIELHTGRYADAHSVAERACELARIRDGVEVGLSHGLIVNAGHGLHYHNAEAIAAIRGVNELNIGHAIVAHALFVGFKQAVKEMKHLILSAAARG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
Protein: CDPAS_HALWD
Sequence: MDMIIEVVATAVWTMLPAYVPNNVAVLTGGGAPIDGGRTLGGRRILGDGKTWRGTGFGTLAGVAVALGLNTILPILTRVGADLTPFSLEAAVGLAFGAMLGDIVASFFKRRSGRRRGVPFPVIDQLDFVVGGILCAVILAPRWVIATFTPPVVIAVFILTPILHLGTNAGAYVLGFKKEPY
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOH_BUCAP
Sequence: MTNKVQILSVTALGNLDAYIRIANLWPMLSIKEEKLLTKRLRYHDDLDAAKTLILSHLRFVIHISRNYSGYGLLQADLIQEGNIGLMKAVRRFNPDIGVRLVSFAVHWIKSEIHEYVLRNWRIVKVATTKSQRKLFFNLRKNKKRLGWFNQEEIEIVARELGVSSEDVREMESRMSAQDITFNPFPEEDLKDGKINGNMFYLQDKTSNFANGLEQDNWNKHTTSKLSNALLRLDERSRNIIRARWLDKKEKNTLQKIANNYGISAERVRQLEKNAMKKLKIAIEN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of expression of heat shock genes.
What are the official names of this protein?
RNA polymerase sigma factor RpoH, RNA polymerase sigma-32 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BP26_BRUA1
Sequence: MNTRASNFLAASFSTIMLVGAFSLPAFAQENQMTTQPARIAVTGEGMMTASPDMAILNLSVLRQAKTAREAMTANNEAMTKVLDAMKKAGIEDRDLQTGGIDIQPIYVYPDDKNNLKEPTITGYSVSTSLTVRVRELANVGKILDESVTLGVNQGGDLNLVNDNPSAVINEARKRAVANAIAKAKTLADAAGVGLGRVVEISELSRPPMPMPIARGQFRTMLAAAPDNSVPIAAGENSYNVSVNVVFEIK
What are the official names of this protein?
26 kDa periplasmic immunogenic protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS4_ACET2
Sequence: MIIYPAVDIKDGRCVRLVQGEFDKVTVYSDNPVEMGLKWERMGAQYLHVVDLDGARTGQIQNTPIISEMAVKLGIPVQLGGGIRTVETIETLLCKGIHRVILGTSAVKNPELVKQALKTFEDSVVIGIDAKDGMVAIEGWAKTSEFTAIGFAKKMEELGAKTIIYTDISRDGMLAGPNLKAMEEMVKAVNIEVIASGGVRNIDDIRNLKNVGVSGVIVGKALYTGDLDLKEAIEVAK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_NOSS1
Sequence: MKRKQESKGAGEKRQGAGGRGQGEKKQGKQGRQGRQGRQGEKSPVPSPQSPIPNPQFTTPNPDEWLQIGKIVSAQGLSGEVRVYPDSDFPERFEVPGTRWLLRPGQTEPQPIELLHGRYLENKNLYVLQLAGVENRSQSEELRGCMLFVPASDRPELGEDEYHVVDLIGMEVFLQASGDLVGAVVDVIPAGNDLLEVSLHEPVTSDKKPKTVLIPFVKAIAPVVDLQTRRIEITPPPGLLELGSGV
What is the function of this protein?
Essential for efficient processing of 16S rRNA.  Probably part of the 30S subunit prior to or during the final step in the processing of 16S free 30S ribosomal subunits.  It could be some accessory protein needed for efficient assembly of the 30S subunit.  It is needed in a step prior to RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity).
What are the official names of this protein?
Probable 16S rRNA-processing protein RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXLD_BACSU
Sequence: MTQTEIIITVAACLIVLAQGIFLFIDAKKRNHMAWVWGIVGLIQAPMPLICYYFFVIRPDRKKRGIKQ
What is the function of this protein?
Together with YxlE, is important for negative regulation of sigma Y activity, being the major negative regulator.
What are the official names of this protein?
Negative regulatory protein YxlD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_STAA1
Sequence: MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RIR1_MOUSE
Sequence: MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTPEHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGALEASCELAKEYGPYETYEGSPVSKGILQYDMWNVAPTDLWDWKPLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKALKEEEEKERNTAAMVCSLENREECLMCGS
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_THEFY
Sequence: MSTDVSTLIDRYVRDIPDYPQPGVVFKDITPLLSHPTALRTAIDALAEPLLGSEIDLVAGLEARGFIFAAPVAVRLGAGFVPLRKAGKLPAETLAESYDLEYGTATVEMHADAVPPGSRVLIVDDVLATGGTGRAAVDLIRRAGGTVVGLSVLLELGFLKGREKLADVELRALATV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_SULAC
Sequence: MNIDEKIKLITRNTDEVITIDELKKKLEENSKLKGYIGFEPSGLFHIGWLIWAQKLKDLIKAGVDMSILVATWHAMINDKLGGDLEKIKLAGKYALEVLEGFGVDMSKLKVVYAEDLVENIDYWSLVVKVAKNTSLARMKRALTIMGRRSEEAELDTSKLIYPAMQVSDIFFQDLDIALGGTDQRKAHMLARDVAEKLQRKKVIAIHTPLLVGLQGGQRMNTEGLEEDDYLATIKMSKSKPETAIFIHDSPELVESKLKNSYCPKGVVNDNPVLQINKYIIFGEQGVTLKIERDTKYGGDIEIKSYEELERIFIEGKLHPLDLKLATARKLNDILDPIRKRISSKSQFVDLISSIEKSITR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AXE2_GEOSE
Sequence: MKIGSGEKLLFIGDSITDCGRARPEGEGSFGALGTGYVAYVVGLLQAVYPELGIRVVNKGISGNTVRDLKARWEEDVIAQKPDWVSIMIGINDVWRQYDLPFMKEKHVYLDEYEATLRSLVLETKPLVKGIILMTPFYIEGNEQDPMRRTMDQYGRVVKQIAEETNSLFVDTQAAFNEVLKTLYPAALAWDRVHPSVAGHMILARAFLREIGFEWVRSR
What is the function of this protein?
Acetylxylan esterase involved in the degradation of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Cleaves acetyl side groups from the xylose backbone units of the hemicellulolytic polymer xylan and xylo-oligosaccharides.  Hydrolyzes about 20%-30% of the available acetyl groups on fully acetylated birch wood xylan.  Completely deacetylates xylobiose peracetate (fully acetylated), and is active on both the alpha- and beta-forms of the sugar.  Also hydrolyzes fully acetylated methyl-beta-D-xylopyranoside and methyl-beta-D-glucopyranoside, and the synthetic substrates 2-naphthyl acetate, 4-nitrophenyl acetate, 4-methylumbelliferyl acetate, and phenyl acetate.
What are the official names of this protein?
Acetylxylan esterase, Acetyl-xylooligosaccharide esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.