PharMolix/UniProtQA huggingface dataset:
Protein: CHI4_METAN
Sequence: GAKNGVHPPLGWIPIQDARIRQHGYNVISAAFPVILPDGTALWEDGMDANVKVATPAEMCQAKAAGATMVMSIGGAAAAIDLSSSSVADKFVSTIVPILKRYNFDGVDIDIEAGLSGSGTFGTLSASQANLVRIIDGILAQMPSNFGLTMAPETAYVTGGSVTYGSIWGAYLPIIKKYADNGRLWWLNMQYYNGAMYGCSGDSYEAGTVKGFVAQTDCLDKGLVIQGTTIRVPYDKQVPGLPAQSGAGGGYMSPSLVGQAWDHYNGSLKGLMTWSINWDGSK
What is the function of this protein?
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Participates in the infection process and directly acts in the penetration process of the host cuticle (By similarity).
What are the official names of this protein?
Endochitinase 4, Chitinase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2923_ARATH
Sequence: MGNFNFLPLVSFASFVVVLVLVCAQDQSGFVSIDCGIPEDSSYYDEKTDIKYISDAAFVESGTIHSIDSKFQKKNLEKQFQKVRSFPEGKKNCYDVQPPQGKGFKYLIRTRFMYGNYDNLGKAPDFDLYLGVNLWDSVTLENSTTIVTKEIIYTLRSDKVHVCLVDKERGTPFLSVLELRLLKNNIYETASDSLMLYRRWDLGATGDLPARYKDDIFDRFWMPLMFPNFLILNTSLMIDPTSSNGFLPPSVVMSTAVAPMNSSIEQIMVYWEPRDPNWKFYIYIHFAEVEKLPSNETREFSVFLNKEQIDTTSVFRPSYLYTDTLYVQNPVSGPFLEFVLRQGVKSTRPPIMNAIETYRTNEFLDLPTDQNDVDAIMKIKTKYKVKKNWLGDPCAPFGYPWQGINCSYTANNPPRIISVNLSFSGLTGQIDPVFITLTPLQKLDLSNNRLTGTVPDFLANLPDLTELNLEENKLTGILPEKLLERSKDGSLSLRVGGNPDLCVSDSCRNKKTERKEYIIPSVASVTGLFFLLLALISFWQFKKRQQSVKTGPLDTKRYYKYSEIVEITNNFERVLGQGGFGKVYYGVLRGEQVAIKMLSKSSAQGYKEFRAEVELLLRVHHKNLIALIGYCHEGDQMALIYEYIGNGTLGDYLSGKNSSILSWEERLQISLDAAQGLEYLHNGCKPPIVHRDVKPTNILINEKLQAKIADFGLSRSFTLEGDSQVSTEVAGTIGYLDPEHYSMQQFSEKSDVYSFGVVLLEVITGQPVISRSRTEENRHISDRVSLMLSKGDIKSIVDPKLGERFNAGLAWKITEVALACASESTKTRLTMSQVVAELKESLCRARTSGDSGDISFSEPTEMNVSMTVDPGVLPQPR
What are the official names of this protein?
Putative leucine-rich repeat receptor-like serine/threonine-protein kinase At2g19230.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RL31_ALIB4
Sequence: MKKDIHPDYKVCTVTCACGNSFETKSNVETLKIDICSSCHPFFTGEQKLVDAAGRVEKFKAKYNMAK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RK2_HELAN
Sequence: MAINLYKTSTPSTRNGTVDSQVKSNPRNNLIYGQHHCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYRDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKNLGRAGSKRWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGKRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ALG1_ARTBC
Sequence: MTLVLLLSIFAICFSSVAFIQLLPTRREKKSSEAHDAVSVQIDTIVCLLRPPRSSSNSPTLNRVADSTPNQELLDHPLISIVALPSPPALLQTKKKFLFPVAAILKVLQQAWHLWAALGYRTGPAHWILVQNPPAAPTLALALLACHLRHSRLIIDWHNFGYSILALKLGSGHPMVKLMEWYEKAFSCYATAHFCVSNAMARILREQFEIKKPLMVLHDRPSSAFSPIFDEKQRLAILSSIPETSQSAIDIIEGRCRLLVSSTSWTPDEDFSLLLDALCRYSTSAKSSGLPSVPLLVIITGKGPLKDMYLSQIDKLKAEGKLFNVFIKTAWLSFEDYAQLLACATLGVCLHTSSSGVDLPMKVVDMFGAGLPVVGWDQYEAWPELVTEGVTGLGFDSADRLSGLLKSVLGGDGSALKVLREGAVKESRNRWDQTWDPIAGTFLGLVT
What is the function of this protein?
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation.  Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: 1433_FUCVE
Sequence: MASRDDLVYMAKLAEQAERFDEMVDHMKAVAQQPKELSVEERNLLSVAYKNVIGSRRASWRVISSIEGKDTVSDQLPLIRDYKSKIETELTDICADILKIIEAELIPNSTSEEGKVFYYKMKGDYHRYLAEFQSADERKTSASDALDAYQLASDHANQDLPPTHPIRLGLALNFSVFYYEILNSPDRACGLAKAAFDDAIAELDTLSEESYKDSTLIIMQLLRDNLTLWTSDQGEAEEAPGNADGTVVEDL
What are the official names of this protein?
14-3-3-like protein.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: ACKA_CAMFF
Sequence: MKILVINSGSSSIKFKLYDMSDESVICKGLIEQIGAKNSYAKIVTKTGEIAEKREEIPDHGTGIDVMNELLFNSHALTSLDEIDGVGHRVVQGADLFNDAVLVDDDVLQKIEELIPLAPLHNPAHLAGMKETLKVRPDIPNVAVFDTVFHQTMPKSSYMYPLPIEFYEKYKIRRYGAHGTSHQFVAKAGAKILGVDFDHFSCITLHLGNGASIAAIKNGKCIDTSMGLTPLEGLMMGTRCGSIDPAIVPFLMKNANLSGEEIDTIMNKKSGLLAIGGSNDMREIEARMDAGDENAKLAFEMFVLRIKKYIGAYISILGEINAIIFTAGIGENDARIREAVCSGLEIFGIRMDKDKNAAKKDEPRRVGLPETKVRIIIVPTDEELAIAEDTLRIINQSKK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFH5_COCIM
Sequence: MEKVQEQPAQTLSETAEQPAERVVEQPQDSAATAAPPGDSKEAETEKPAEVAPKEDSKEAPAPPPAATTAATADDANSDIIEEVKDKAGANTQVADPKPQEPADTRPSYLVNNAALSQFFDRLAPIVEKAGHNEMWGVPLKDAQDAPTVNIMIKFLRANEGNVKLAEEQLVKALEWRKKMNPLALAESAAFPSSKFKGLGYITTYRDPTTEKNVVFTWNIYGSVKNVDLTFGNLEEFIKWRVALMELAIRELRLESATSVMDYNGEDPYQMIQVHDYQNVSFIRMNPNIRAASRETIEVFSTAYPELLKEKYFVNLPVVMGWVFTALKVFLSKNTIRKFHPITNGVNLAREFTTFGEEIPKTYGGKGDVLADSGRTVTLQDDKAPETKPEENGNASQAPEAEPASGNPAQTDATNGPAKDDAPKNDKPAVPTDTKTDAPADAPANTLADAPADSRPN
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein SFH5, PITP SFH5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DIAA_SHIF8
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISARGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: TIG_CALBD
Sequence: MEFKIEKKGTNKAIIEVEVEAEKFEEGLQKSYLKNAKYFKIPGFRPGKAPRSLIERAYGEEVFYDDAIDYVLNETYPKVIEESKLEVVSRPEVDIVQVGKGKSFIYKAEVYVKPEFELGQYKGVEITKIEYPVAEEEVEHELEHLREENARFVPVERPVENGDIVTIDFEGFVDGEPINGGSAKDYELTIGSNTFIPGFEEQLIGMNKGEEKEIEVTFPEDYQEPSLAGKKATFKVKVKDIKVKELPELDDEFAKDVSEFETLEELKANIRNRIREKNDKRAKDEMIDAILEKIAQNTSIDIPEPMIENQINYYVEDVARNLQYFGMTYERYLQAIGKTDKEFRSQFRERAEKAVRNNLILEKIAKVENIQATEEELQKELERLAKMYNLEVDKLKERLSEDDIEYIKEGIILNKAIDFIYENAKIISEDNQGENQEN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: S2536_HUMAN
Sequence: MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
What is the function of this protein?
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria.  Selectively transports cytosine, guanosine, inosine and uridine (deoxy)nucleoside mono-, di-, and triphosphates by antiport mechanism.  Catalyzes uniport at much lower rate (PubMed:25320081).  May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside mono- and diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism (PubMed:25320081).  Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration.
What are the official names of this protein?
Solute carrier family 25 member 36.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: MURI_SALG2
Sequence: MATKLQDENTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRRLLPDLHYIYAFDNVAFPYGEKSETFIVERVVEIATAVQQRYPLSLAVIACNTASTVSLPALREKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAMLGSAELVELAEAKLHGDSVSLEELRRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGAEQLLPILQRYGFETLEKLPV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: H2E01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFERSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1ab, U4-TRTX-Hhn1ab, Hainantoxin-II-5, HNTX-II-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HCP_YERPA
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLVAVLQGLSAWALQARELGIIDSQIDSFAPRAFFSTLTNVNFDSDRIVEYAKDAILLRHSLAVRCRLLDSTITVDHPLAELQLVADDIPSLLQQSQQFALNNDKADVGDDIHGLRMLCLYGLKGAAAYMEHAHVLGQSDEQIYAEYHAYMAWLGTQPRDVDTLLNNAMGIGKMNFNVMAILDQGETQAYGDPQPTSVNVRPVAGKAILISGHDLKDLHMLLEQTQGTGINIYTHGEMLPAHGYPELKRYPHLVGNYGSGWQNQQTEFAKFPGPILMTSNCIIDPNVGNYGDRIWTRSIVGWPGVNHLDGDNFAPVIEQALGMAGFPYSELEHLITVGFGRQTLLNAADTVIDLVASKKLRHVFLVGGCDGSRTERSYFTDFARSVPQDCIIMTLACGKYRFNKLDFGTLEGLPRLLDVGQCNDAYAAIMLAVKLSEKLGCTVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIYTGPTAPGFLTDNLMAILYEKFGMQPITTVEQDMQAILGH
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA1_STAAW
Sequence: MGIIAGIIKVIKSLIEQFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.  Stimulates the secretion of the chemotactic factor interleukin-8 (IL-8).  The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virulence.  Also possesses hemolytic activity, which may contribute to the development of disease.
What are the official names of this protein?
Phenol-soluble modulin alpha 1 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: RLMC_HAEIE
Sequence: MIDCQYYQQNECRSCQWLEIPYDQQIAEKQHHLKQQLISLDCSDVHWLAPFKSNEQGFRNKAKMLVSGSVERPILGILKNPNDPQSAIDLCDCPLYPAHFSIIFSILKDFIGRAGLVPYNIAKQKGELKYILLTESIATGKLMLRFVLRTENKLPLIRRELPKLLEKLPHLEVISINLQPQHAAILEGEQEIFLTEQQFLPENFNGIPLFIRPQGFFQTNPKVAAGLYATAQQWVAEFPIYNLWDLFCGVGGFGLHCAKALQEKWGKPIKLTGIEISSSAILAASHSAKILGLEHVNFQSLNAASVMENKNENKPDLVIVNPPRRGIGKQLSEFLNQIQPHFILYSSCNAMTMGKDLQHLTCYKPLKIQLFDMFPQTSHYEVLVLLERKKIN
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: ORP4B_ARATH
Sequence: MAEEEMRKHLVLAKPFSLEDEKDSEHTASNVIRKILSLFKTVRPGSDLTNFQLPPQLNLPRSQLQCYGEMVYSFVGQDLLGECSRRDLPIERLKSVVTWNISTLRPVVFGMSPYNSVLGETHHVSNGHINVIAEQVVHHPPVSALHATHEQENIDVTWCQYFTPKFRGTHVDVEVKGKRVMKLLNHIETYEMDQPRLIMRFLPAPGAYWAGKVKIKCPETDLEAELHLISDSFIERFRGNNNRSIKGKIFESSSGNQLYNIFGHWDRTVMAKNIKTGELEVIYNAKENITGLKPPTVKNLEEVTESESTMVWSEVSEGILKKDWERAREAKIVVEEKQRASLKQREASGESWVPKHFLVVKDGKDWDCSPLQPTVPPAPLVIT
What is the function of this protein?
May be involved in the transport of sterols.
What are the official names of this protein?
Oxysterol-binding protein-related protein 4B, OSBP-related protein 4B.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: NAGD_STAAM
Sequence: MKQYKAYLIDLDGTMYMGTDEIDGAKQFIDYLNVKGIPHLYVTNNSTKTPEQVTEKLREMHIDAKPEEVVTSALATADYISEQSPGASVYMLGGSGLNTALTEAGLVIKNDEHVDYVVIGLDEQVTYEKLAIATLGVRNGATFISTNPDVSIPKERGLLPGNGAITSVVSVSTGVSPQFIGKPEPIIMVKALEILGLDKSEVAMVGDLYDTDIMSGINVGMDTIHVQTGVSTLEDVQNKNVPPTYSFKDLNEAIAELEK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
What are the official names of this protein?
Acid sugar phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NagD family.
Protein: SYGB_LATSS
Sequence: MTKPFLLEIGLEEMPAHVVMPSIQQLEKRVRDFLEEQHLEFGQLKTYATPRRLAILIEDLADKQADIHEEAKGPAKKIALDAEGNWSKAAQGFVRGQGLTTDDITFKELKGVEYVYVEKSIIGKPVEAILPELKAVIMAMTFPTRMHWADYDFEYIRPIHWIIALLDDEVIDFSILNVTTGRTTQGHRFLGQEVTLAKATDYEAALEAQFVIADEAKRQNLIQTQIEKMAQENDWQVDLDANLLEEVTNLVEWPTAFYGQFDAKYLEIPEEVLITSMKDNQRYFYARSQAGDLLPVFIGVRNGNDAFMENVIAGNEKVLTARLEDADFFYHEDQKVTIAENVAKLQNVSFHDKIGSLAEKMTRVGLIAQFLGQKFGLSEAELVDLQRASDIYKFDLVTGMVGEFAELQGVMGEKYALLQGETPAVATAVREHYMPISAEGALPATKVGAVLAIADKFDSMADFFAVGMIPSGSNDPYALRRQAYGIVRILENQDWHFPMADFQAAMSHIVKQQADFDLDWSANAAAISDFLTDRVRQRFNGMRPKVRRDIVDAVLKNQGQDPVVMFEAAKVLSAHQDDADFKATIEAITRVLRLAEKVDFETTDLTVDPALFENDAEKALYTAVEDLRGATATNTLAENYAALQTLRPLIEAYFDATMVMAEDEAVRRNRLTQLMIIAQIALSLGDLNELIVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF_BACSU
Sequence: MPLVSMTEMLNTAKEKGYAVGQFNLNNLEFTQAILQAAEEEKSPVILGVSEGAGRYMGGFKTVVAMVKALMEEYKVTVPVAIHLDHGSSFESCAKAIHAGFTSVMIDASHHPFEENVATTAKVVELAHFHGVSVEAELGTVGGQEDDVIAEGVIYADPKECQELVERTGIDCLAPALGSVHGPYKGEPNLGFKEMEEIGKSTGLPLVLHGGTGIPTADIKKSISLGTAKINVNTENQISSAKAVRETLAAKPDEYDPRKYLGPAREAIKETVIGKMREFGSSNQA
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Probable fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: SODE_CAEEL
Sequence: MKTRVVLILALSVCIEAASEVIRARAYIFKAEAGKIPTELIGTIDFDQSGSFLKLNGSVSGLAAGKHGFHIHEKGDTGNGCLSAGGHYNPHKLSHGAPDDSNRHIGDLGNIESPASGDTLISVSDSLASLSGQYSIIGRSVVIHEKTDDLGRGTSDQSKTTGNAGSRLACGTIGTVEERILETTTASLPPVTQSQPIGSSSYYYSTFYLPIILYFLLSRIL
What is the function of this protein?
Protects cells against oxidative stress by converting superoxide radicals to hydrogen peroxide (PubMed:9628580).  Oxidative stress is involved in various biological dysfunctions and senescence (PubMed:9628580).
What are the official names of this protein?
Extracellular superoxide dismutase [Cu-Zn], EC-SOD.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Peripheral membrane protein.
Protein: HUTG_PARXL
Sequence: MRVPFNDKVWAGRSDDGEAGDTRRVFNQVTPFGSAVRVQHDAPVIVGFSSDEGVRRNQGRIGAAHAPMELRRVLAGLPAKTAMVALADAGDVVCDDGDLEAAQAELADVVSEVLAGGGRPLVLGGGHEVAWGTYSGLRLHQQREAENEATLLISRKLLIINFDAHFDLRQKRPANSGTPFDQIALDCAERGVPFNYACFGISDLSNTASLFAHAERLGVHYVFDVDMQETQLPQRLNELQKLLDAADDVYLTIDLDVLPAATAPGVSAPAALGVPLSVIEAMVLRVRASGKLRVADIAEYNPTLDQDRRTARVAARLAYRLL
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RK33_NANDO
Sequence: MAKGKDVRIRVILECNSCVRNDLNKESPGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EGC2_ARATH
Sequence: MIKMAVKFVVVMIVFAQILAPIAEAAQGKAVYYDPPYTRSACYGTQRETLVVGVKNNLWQNGRACGRRYRVRCIGATYNFDRACTGRTVDVKVVDFCREPCNGDLNLSRDAFRVIANTDAGNIRVVYTPI
What is the function of this protein?
Plays a systemic role in water and solute homeostasis.
What are the official names of this protein?
EG45-like domain containing protein 2, Plant natriuretic peptide A, AtEXPR3, AtPNP-A, Ath-ExpGamma-1.2.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMN_CERS5
Sequence: MTATAPITQDVMTLPRKLPEGGPLNIVGLTREELMAALVAAGTPERQARMRMGQVWQWVYHWGVRDFAQMTNLAKDYRALLAEHFAIVLPEVVTRQISADGTRKYLIRIAGGHEVETVYIPEEGRGTLCVSSQVGCTLTCSFCHTGTQKLVRNLTAGEIVGQVMLVRDDLGEWPERGAPKDETRLVSNLVLMGMGEPLYNFENVRNAMKVVMDGEGLSLSRRRITLSTSGVVPEIARTAEEIGCQLAISFHATTDEVRDILVPINKRWNIRTLLDSLRDYPRLSNSERITFEYVMLDGINDSDADARRLVKLISGIPSKINLIPFNEWPGAPYRRSTPERIAAFADIIYKAGYASPIRTPRGEDIMAACGQLKSATERARKSRAQIAAETGL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2729_NITWN
Sequence: MAGHSQFKNIMHRKGRQDAQKSKLFSKLAREITVAAKLGTPDPAMNPRLRAAVIAARAENMPKDNIERAIKKASGNDAESYDELRYEGYGPGGVAVIMEVLTDNRNRAASDIRSYFTKSGGNLGETGSVSFMFDRLGVIEYDADKASVDDMLEAAIEAGADDVVSDEGGHEIYASQDTFRDVAKALESTFGEARKVALIWKPQNTIAVDDNTGEKLLKLIDLLNEHDDVQNVYANFEVSDALIAKLGG
What are the official names of this protein?
Probable transcriptional regulatory protein Nwi_2729.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_CHLTB
Sequence: MKETIAYLGMGMWGFSLANLLANNGHRVVGWARNPALIEQLSVQRRHPAAPHISIPQNLSFTSHMEEALDGATMIVEGVTSAGMRPVLTQLKALTELRVPLVITSKGIEQNTGLLLSEIALEIFGRPAAQHLGYLSGPSIASEVLRGCPCSVVISAYNPDTLKQIHRAFLTPTFRVYPNSDLKGVALGGALKNVIAIACGISDGFRFGDNAKSGLVTRGLHEIRKFATIMGCRPDTLNGLAGLGDLCTTCFSAFSRNTLFGKLLAEGLTPEQAKTKIGMVVEGVYTALSAHQIATHHRIDMPITTSVYRVLYENLDIQEGIAQLLQRDTKEEYL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_HAMD5
Sequence: MEFKVNSECSEKQSSDCIVIGIFESGEFSPSAEKVNKISHGYLKGLPQNADLQGKAEQALLLHHVPHVAAERVLLIGCGKEEELDERRYKKLIKKMVNTLKETGAKNVFCYLPELKVKGKDIDWKIRSAIEVIQDALYCFDHYKSTKTLHALNQITFIVTATQTKAAQTAIQEGIALAVGINEAKNLANTPPNICNPAYLNASARKWAEKFKNVRVSVVNEDEMKKLGMNAYLAVGQGSKNESLMSIIEYKSGKIPAGTKPIVLVGKGMTFDSGGISIKPSQNMDEMKYDMCGAATVFGVMNVVAELNLPLYVIGVLAGAENMPGGNAYRPGDILTTLSGQTVEVLNTDAEGRLVLCDALTYVERFDPELVIDIATLTGACVVALGHHMSGLMSNHAPLAEDLLHASEQSGDLAWRLPLGEEYQEQLDSNFADMANIGGRTAGAITAGCFLSRFTHQYHWAHLDIAGTAWRTGKEKGATGRPVALLSQFLLNKALAQKQGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO4F2_RAT
Sequence: MMMMSLNSKQAFSMPHAGSLHVEPKYSALHSASPGSSAPAAPSASSPSSSSNAGSGGGGGGGGGGGGGGRSSSSSSSGSGGGGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDATYHTMNTIPCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGTVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAGI
What is the function of this protein?
Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells.  Functions either as activator or repressor modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner.  Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes.  Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation.  Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding.  Inhibits DLX1 and DLX2 transcriptional activities preventing DLX1- and DLX2-mediated ability to promote amacrine cell fate specification.  In cooperation with TP53 potentiates transcriptional activation of BAX promoter activity increasing neuronal cell apoptosis.  Negatively regulates BAX promoter activity in the absence of TP53.  Acts as a transcriptional coactivator via its interaction with the transcription factor ESR1 by enhancing its effect on estrogen response element (ERE)-containing promoter.  Antagonizes the transcriptional stimulatory activity of POU4F1 by preventing its binding to an octamer motif.  Involved in TNFSF11-mediated terminal osteoclast differentiation.
What are the official names of this protein?
POU domain, class 4, transcription factor 2, Brain-specific homeobox/POU domain protein 3B, Brain-3B, Brn-3B, Brn-3.2.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.