PharMolix/UniProtQA huggingface dataset:
Protein: MARC_SHISS
Sequence: MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNME_YERPS
Sequence: MSTTDTIVAQATPPGRGGVGILRVSGRAASEVAHAVLGKLPKPRYADYLPFKDVDGSTLDQGIALYFPGPNSFTGEDVLELQGHGGPVILDLLLKRILALPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSAVNSLQGAFSARIHQLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEGQLNGVMADLEQVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREANDEVERIGIERAWNEIEQADRVLFMVDGTTTDATEPAAIWPEFMARLPATLPITVVRNKADITGETLGLTKVNGHSLIRLSARTGEGIDLLRDHLKQSMGFTSNTEGGFLARRRHLQALETAARHLVQGHEQLVSAYAGELLAEELRLAQQSLSEITGEFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB202_ARATH
Sequence: MGSSLCVAVRKKEKQKQKKTVVFLPEIPEEMLIDILIRLPAKSLMRFKCVSKLWLSLITSRYFTNRFFKPSSPSCLFAYLVDRENQSKYLLLQSSSSSRHDHSDTSVSVIDQHSTIPIMGGYLVNAARGLLCYRTGRRVKVCNPSTRQIVELPIMRSKTNVWNWFGHDPFHDEYKVLSLFWEVTKEQTVVRSEHQVLVLGVGASWRNTKSHHTPHRPFHPYSRGMTIDGVLYYSARTDANRCVLMSFDLSSEEFNLIELPFENWSRTIHMNYQGKVATCQYMRLASDGFVDVCVLEDADKSQWSNKKTFVLPISQMNFVHGDRLVVGASRDSGKVLMRKANLLRNQHARFFLYDMERNEIARRIEIRPSLLGSFNKTNQFLKVCYTFQTK
What are the official names of this protein?
Putative F-box protein At3g52320.
Protein: COAD_CAMC5
Sequence: MKRSCIYPGTFDPITNGHLDVIKRAVKIFDRVIVAVAKSDSKNPMFGFDERVTMVERSVEGLKNVSVEGFDNLLVDFAKSHEINTVIRGLRAVSDFEYELQIGYANAALWSEFETVYLMPSLKNAFISSSIVRSVLRHDGDVSALVPSQIFSLLKG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAZF1_HUMAN
Sequence: MTGIAAASFFSNTCRFGGCGLHFPTLADLIEHIEDNHIDTDPRVLEKQELQQPTYVALSYINRFMTDAARREQESLKKKIQPKLSLTLSSSVSRGNVSTPPRHSSGSLTPPVTPPITPSSSFRSSTPTGSEYDEEEVDYEESDSDESWTTESAISSEAILSSMCMNGGEEKPFACPVPGCKKRYKNVNGIKYHAKNGHRTQIRVRKPFKCRCGKSYKTAQGLRHHTINFHPPVSAEIIRKMQQ
What is the function of this protein?
Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2 (PubMed:15302918).  Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity (By similarity).  Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD (By similarity).  Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue (By similarity).  Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity (By similarity).
What are the official names of this protein?
Juxtaposed with another zinc finger protein 1, TAK1-interacting protein 27, Zinc finger protein 802.
What are the subcellular locations of this protein?
Nucleus.
Protein: SMN_DROME
Sequence: MSDETNAAVWDDSLLVKTYDESVGLAREALARRLADSTNKREEENAAAAEEEAGEISATGGATSPEPVSFKVGDYARATYVDGVDYEGAVVSINEEKGTCVLRYLGYENEQEVLLVDLLPSWGKRVRREQFLIAKKDEDEQLSRPKASAGSHSKTPKSSRRSRISGGLVMPPMPPVPPMIVGQGDGAEQDFVAMLTAWYMSGYYTGLYQGKKEASTTSGKKKTPKK
What is the function of this protein?
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm, is required for pre-mRNA splicing in the nucleus and acts as a chaperone that discriminates target and non-target RNAs of Sm proteins.  Required for normal expression of spliceosomal snRNAs and for U12 intron splicing.  Required in cholinergic neurons, but not in motor neurons, to ensure correct splicing and proper levels of stas mRNA and normal neurotransmitter release by motor neurons (PubMed:23063130, PubMed:23063131).  However, Smn is required in motor neurons, but not in cholinergic neurons, for normal motor behavior but plays no role in synaptic transmission according to a report (PubMed:23103409).  In both muscle and neurons, required for the formation of a normal neuromuscular junction (NMJ) structure.  Plays a neuron-specific role in long-term homeostatic compensation at the larval NMJ.  In the thorax of adult flies, required for Act88F, an indirect flight muscle (IFM)-specific actin, expression and for proper IFM myofibril formation.  In nurse cells, oocytes and follicle cells, required to maintain normal organization of nuclear compartments including chromosomes, nucleoli, Cajal bodies, histone locus bodies and heterochromatin.  Required for the functional integrity of the cytoplasmic U snRNP body (U body) and P body.  Required in dividing postembryonic neuroblasts (pNBs) for the correct basal localization of mira.  The tight regulation of its expression is critical for stem cell division, proliferation and differentiation in male germline and developing central nervous system (CNS).  Required for tracheal terminal cell lumen formation.
What are the official names of this protein?
Survival motor neuron protein.
What is the protein family that this protein belongs to?
Belongs to the SMN family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, gem. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, Z line. Note=Component of U bodies. High expression detected in the cytoplasm of female germline stem cells and cystoblast which persists up to stage 10 egg chambers. Accumulates in the cytoplasm of dividing pNBs. Colocalizes with Actn at the Z-line of IFMs. Expression concentrates at the post-synaptic region of NMJs in larval brain.
Protein: HEM1_PARPJ
Sequence: MQLLTIGINHHTAPVALRERVAFPLEQIKPALETFKSIWLGPSARTAPEAAILSTCNRTELYCATDDQAAREAAIQWLSRYHNLPIDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQIVGQMKDAVRTASEAGALGTYLNQLFQRTFAVAKEVRSTTEIGAQSVSMAAAAVRLAQRIFDKVSNQRVLFIGAGEMIELCATHFAAQQPRELVVANRTAERGTRLAERFNGRAIPLSELPSRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGQLEDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADVLRRAEVERAQKMLARGDDPAAVLEALSQSLTNKLIHGPTHALNRASSENRDKLIELMSGFYKHSGSTER
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ISCX_ECO57
Sequence: MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDDDPQASNEKILEAILLVWLDEAE
What is the function of this protein?
May function as iron donor in the assembly of iron-sulfur clusters.
What are the official names of this protein?
Protein IscX.
What is the protein family that this protein belongs to?
Belongs to the IscX family.
Protein: PLSB_SHEWM
Sequence: MSKQDSLWFKSLRWLQKKLVHTIVVPQEPFKDLNLDPEKPLVYVMKTESLSDIAALSEITGELGLPSPYEPLEVEGRSTPRVVCLEGAKPLMGKRESNEFFLSSFMDLLKAHKESPDLDIQLVPVSLYWGRTPGKEDDTMKAAVLERENPTWLRKCLMILFLGRHNFVQFSNSVSIRYMADEHGTDKRIAHKLARVARVHFSRQRKVMTGPVLPKRQALFHALINSESLKRAIQEEATSKKISEVEARAKAMEYLDEIAADYSDSLVRIAERFLTWLWNKLYKGINIKGAEQIRQLHHDGHEIIYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPMFRRGGAFFIRRSFRGNKLYTAVFREYLDQLFTKGYSVEYFTEGGRSRTGRLLAPKTGMIAMTLNSVLRGMERPVTLVPVYLGYDHVMEVATYHKELSGKKKKKESVWQVFGALRKLGNFGQGYVNFGKPITLHSFLNEQVPDWREEIASDPEQKPTWLTPVVNTLANQVMTNINDAAAVSSVTLTSLVLLASEQNALERTQLEKQLDLYLKLLKDLPYTSYTSVVEGDGKQLVTQGLELKKLQLDSDPLGDIVSIDESISIAMTYYRNNIIHLMIIPSLVASCLTQHERITRDEIKAIIADFYPLLEAELFMGVEDTDKLVEQILDLFIEQQLIREDTGFSVVETSINQLLLLAGTVSETLQRYAIIFNLLADFPEMERSDLEAESHKLAKRLGALHGITAPEFYDKNLYRTLSVKLKDLGYLKDNGNKADVERVRASANGLLRSSVRQTIVDSVAAERSA
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS10_PECCP
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: COQ7_CHRVO
Sequence: MLDKLITELDKGLRTLCAPAHSGRAHPDQDIAEADLSAAEKKHALGLMRVNHCGEVCAQALYQGQALTARDASAREALRQAAQEEVEHLAWTERRIRELGGRPSLLNPLWYTGSLALGVAAGVLGDKWNLGFLQETERQVGAHLDSHLSALPPDDARSRAIVRQMRDDELQHAEMAHELGAAELPAPVKAAMKLSAKVMTGSSYRV
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CARB_STRTH
Sequence: MAALLKRILRRRMAEKRSGRGRMAAARTTGAQSRKTAQRSGRSEADRRRRVHGQNFLVDRETVQRFVRFADPDPGEVVLEVGAGNGAITRELARLCRRVVAYEIDRHFADRLREATAEDPRIEVVAGDFLKTSQPKVPFSVVGNIPFGNTADIVDWCLNARRLRTTTLVTQLEYARKRTGGYRRWSRLTVATWPEVEWRMGERISRRWFRPVPAVDSAVLRLERRPVPLIPPGLMHDFRDLVETGFTGKGGSLDASLRRRFPARRVAAGFRRARLEQGVVVAYVTPGQWITLFEELHGR
What is the function of this protein?
Probable RNA methylase.  Confers resistance to carbomycin and several other macrolides, lincomycin and vernamycin B, but not to all macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA methyltransferase, Carbomycin-resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: RL32_MICAN
Sequence: MACPKKKTSNAKRDQRRAHWRKQAAREAQKALSLGKSVLSGRSNSFVYPTKEEEEGEDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NAGB_YERPG
Sequence: MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIKTLTQETRIANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCDEPSTMELKVKTVKYFRELEAENVKDL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: TRY5_ANOGA
Sequence: MSIKFTTLLAVLFALLAYARAQAERRHKLTRPVHRFAPNRPYLAGKRIVGGFVINISDAPYQISLQYDDDHNCGGSILSSKWILTAAHCINDNAPSKPTVRVGSSKHASGGTVIRVARIVPHPMHGSKNNYDIALLELKNELTFSEKVQPIALPEQDEPIEEGTMGIVSGWGLTLSEADSNDVLRATNVPTVNQQECNKAYQSRYGGITDQMFCAGYKQGGQDTCRQDSGGPFVAKGKLIGVISWGHECALAGYPGVYARVASVRDWIRTTSGV
What is the function of this protein?
Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female.
What are the official names of this protein?
Trypsin-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: MGT4B_MOUSE
Sequence: MRLRNGTFLTLLLFCLCAFLSLSWYAALSGQKGDVVDIYQREFLALRDRLHAAEQESLKRSKELNLVLEEIKRAVSERQALRDGEGNRTWGRLTEDPRLKPWNVSHRHVLHLPTVFHHLPHLLAKESSLQPAVRVGQGRTGVSVVMGIPSVRREVHSYLTDTLHSLISELSPQEKEDSVIVVLIAETDPQYTSAVTENIKALFPTEIHSGLLEVISPSPHFYPDFSRLRESFGDPKERVRWRTKQNLDYCFLMMYAQSKGIYYVQLEDDIVAKPNYLSTMKNFALQQPSEDWMILEFSQLGFIGKMFKSLDLSLIVEFILMFYRDKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFKPSLFQHVGTHSSLAGKIQKLKDKDFGKHALRKEHVNPPAEVSTSLKTYQHFTLEKAYLREDFFWAFTPAAGDFIRFRFFQPLRLERFFFRSGNIEHPEDKLFNTSVEVLPFDNPQSEKEALQEGRSATLRYPRSPDGYLQIGSFYKGVAEGEVDPAFGPLEALRLSIQTDSPVWVILSEIFLKKAD
What is the function of this protein?
Glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains.  Prefers complex-type N-glycans over hybrid-types.  Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, GnT-IVb, N-acetylglucosaminyltransferase IVb, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Note=A processed soluble form also exists.
Protein: SPT16_CRYNJ
Sequence: MSDIRLDSATFFKRAAKIFDSWEKPSGDTQALEDINSIAIILGDPNDEVASYTKTTALQLWLLGYEFPSTLMVFEKSPRKVTFVCGSSKAKLIRQLQPSDGIEIDVKVRSKDATAAKETMEEVVASLNGKFGSLPKDRPIGKLVDEWNSAVESKGDLEVVDVAIPISAVLAEKDGEELKTIITSAKLTSTVMINYFKSKMESIIDRGTKMSHEALAQLVEEKIGNEEKGPDMKLWNKNPSLGEIDFASSEFVYSPVIQSGGKYDLKVTAASNNDNLKPGIILANMGIRYKNYCSNMGRTFLISPSKKQETQYTTLLEVRKEALALLKTGAVASDVYNSVHQSLETKNATLADSFLKNLGFATGMEYRDSSFLLNAKNNRELKENMVLVLTIGVADLPDAKNKGKTYSLLLSDTVKIGQNGAVVLTEGCTRLSDVVMDMEEEEEEDVKPQIDKKPKINNSPKKPRSSTVGGRVLNAKTRGANREQATQTTAEKIKTNQQRLHAQLNADGVKRWEADAGGKNGAQQKVVKRYESYRREEQLPRAVEDRRIYVDEQRQSVVLPINGYAVPYHISTIKNVTKTEESNHMVLRINFQSPGQIAGKKEDMPFEDPDANFIRSVSFRSQDQRHMLKVYEAITALKKAAVKRETERKELADVIEQEKLIEVKGRHPYVLKNVFPRPGPEGKKTDGNVEIHQNGIRFRPDGPASKIDILFSNIKHLFFQPSEKELIVIIHVHLKAPIMLGKKKTSDVQFYREVADMSFDETGGKKRRARYGDEDEIEQEQEDRKRRAELDKLFHDFARRIETAAQAQQFELEVDVPFRELGFNGVPHKSIVALLPTTNCLIHISELPFTVITLSEVEIVHLERVQFGLKNFDMVFVLQDLKKPPVHINSIPVAHLDNVKEWLDSCDVPISEGPVNLSWPAIMKTVNEDPHAFYAEGGWNFLTGSGSDDGSEESEEGSEFEGDSDVFDESSGSDEDSESAFEGDSDSASAESLSDEGEDWDELERKAKRADEKHRTDRGGDSDDDGKKKKKGSRR
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit SPT16, Facilitates chromatin transcription complex subunit SPT16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y1128_CLOBA
Sequence: MQKDVEYIELLDEQGEQTKFKVITYFQIDEINGEYVVVTPAENDDCDEAFVLKVISDEEGNETLVSIEDEKEFDLVEEAYNLVMSEQE
What are the official names of this protein?
UPF0473 protein CLH_1128.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: Y3114_SHEPA
Sequence: MPSMDIVSEVNEVELRNAVDNSVRELKGRFDFRGKEASIEYKDHVVTLTAEDDFQCRQLVDILRMQMSKRDVDPKSMDVDDKAVHSGKTFSLKVKFKEGIETLVAKKLVKLIKDSKLKVQVSIQGDSVRVTGKKRDDLQQVMALARESELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein Spea_3114.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: MNMG_OCEIH
Sequence: MTYNAGNYDVIVVGAGHAGVESAYAAARMGAKTLMLTLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGIMGKVIDKSYIQMRMLNTGKGPAVQALRAQADKPIYMKEMKHLMENEENLTIRQGMVNELIVEDGICKGVITETHAAYYADSVIVTTGTFMRGKVLMGDLEYESGPNNQRVSIKLSEDLEKHGFEITRFKTGTPPRVNSHTIDYSKTEIQPGDDNPKSFSYETTEQITDQIPCWLTYTNEFTHQVINDNLELSSMYSGMKRGTGPRYCPSIEDKIVRFNDKPRHQIFLEPEGRDTEEVYVQGLSTSLPESIQHEMIKSVPGLEKAEIMRAGYAIEYDAVVPTQLWPTLETKRLPGLFTAGQINGTSGYEEAAGQGLMAGMNAAAKSLNKEPIILDRSQAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDIGYDYGLITEERYQRFTEKKQQIEQEKKRLSKIIIKPTEDIQDIMEKAGASRLKEAIKAYDLMKRPELSYDIVDQMIESNLELSEEVKEQVAIQIKYEGYIKKAKEQVDRMLKMEDKKIPEDIDYDAINGIATEAVEKLKKVRPLSVGQASRISGVNPADVSILLVYIEQGSIAKVAND
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_STAA8
Sequence: MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPHR_MOUSE
Sequence: MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKLNLCVILLILVFMVPFYIGYFIVSNIQLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAVARRTMFQRGDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP
What is the function of this protein?
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (By similarity).  Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (PubMed:32220963).
What are the official names of this protein?
Golgi pH regulator, Protein GPR89.
What is the protein family that this protein belongs to?
Belongs to the Golgi pH regulator (TC 1.A.38) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PRS10_BOVIN
Sequence: MADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLGNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EFTS_YERPB
Sequence: MVAITAALVKELRERTAAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRIAAEGIILAKVSADGKYGVILELNCETDFVAKDAGFKAFGEEVINAALAEKIADIDVLKAKFEEQRANLVAKIGENINIRRVAVLEGDILGTYLHGARIGVMVAATGADEELVKHIAMHIAASKPEYVKPDDVPAEVVAREHQIQLDIAIESGKPREIAEKMVEGRMRKFTGEVSLTGQNFVMDPSKTVGDLLKENNADVVNFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_POPTR
Sequence: MRINPTTSGPGVSALEKKNLGHIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVSQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDDLGPVDTQITSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPQIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGELDSLPEQAFYLVGNIDEATAKATNLEMENNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: UVRC_LEGPC
Sequence: MNDLQLSAELALFLTKLPGEPGIYRMLDEEGTVLYVGKAANLKKRVNSYFSKQNTGVKTRALVSQIKSIEISVTRSETEALLLESNLIKALRPKYNVLLRDDKSYPYIHLSNHPDFPRIELYRSKKKPPSGNFFGPYPGVAAVRETIVTIQKIFKIRNCRDSYFKARSRPCLQYQIKRCTAPCVHYISPENYKLSVEDAIRFLQGKCQIILDELAERMKQAVSQLNFEEAAVLRDQIKNLRLIQEQQGVVQLRGDADVIAIEVRPGFACIQCVTIREGQVLNSQSFFPTVPYAVLDEELDANSLWQQTFEAFVGFYYLDTSERIPDLIITNQSITESRSLEYILSQRRGKSCKIQVNPRGVKSRWMDFAVNNLRISVAEYVSKHSTIKSRYQALKQLLALDKNIERMECFDISHTQGESTVASCVVFDTEGPRPSEYRRFNIEGITPGDDYAAMEQAVTRRFKRLIDAQLLPDVLIIDGGKGQVSIVKRVITSLGVEDITLLGVSKGPSRKAGWEKLILVNENREFVLPEDSKALHLLQHIRDEAHRFAITAHRKKRQKTRVESTLESIEGVGTKRRQALLQRFGGLRELAKAPLEEICKVQGINEQLAKRIYEHFHP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.