PharMolix/UniProtQA huggingface dataset:
Protein: SODM_NICPL
Sequence: MALRTLVSRRTLATGLGFRQQLRGLQTFSLPDLPYDYGALEPAISGDIMQLHHQNHHQTYVTNYNKALEQLHDAISKGDAPTVAKLHSAIKFNGGGHINHSIFWKNLAPVREGGGEPPKGSLGWAIDTNFGSLEALVQKMNAEGAALQGSGWVWLGVDKELKRLVIETTANQDPLVSKGANLVPLLGIDVWEHAYYLQYKNVRPDYLKNIWKVMNWKYANEVYEKECP
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GAGT1_ARATH
Sequence: MSLVRTVTIVLFIIAFLQNAAAQKRQQSIVKSRGAVATDDGRCSVIGMRVLREGGNAIDASVAAALCLGVVSPASSGIGGGAFTVVKIAGGKEIAYDSRETAPLRATENMYGGNVDLKKKGALSVGVPGEVAGLFTAWKQHGKLPWKRLVTPAEKLAEGFKISKYLYMQMNATRSDILADKGLSDLFVSNGELKKPGTICHNPKLALTLKLIGEYGPKAFYNGTVGVNLARDIKKSGGIITLKDLQSYRVKIKEPLSADILGYRVLGMPPPSSGGAAMMLVLNILSQYGIPSGVSGPLGVHRLIEALKHAFAVRMNLGDPDFTDVTKVVSDMLSPKFAKDLKSKINDQKTFDPKYYGGMWNQIDDHGTSHLSIIDRERNAVSMTSTINGYFGALMLSPSTGIVLNNEMDDFSIPMKSNGNLDVPPPAPANFIRPGKRPLSSMSPTIVLKDGKVKAAVGASGGANIIAGTTEVYLNHFFLKMDPLSSVLAPRIYHQLIPNRASYENWTTVFNDHFEIPKATRVVLEKKGHVLSPIAGGTIAQFIVQESGENSGGRSELVAVSDPRKGGFPSGY
What is the function of this protein?
May play a role in preventing oxidative stress by metabolizing extracellular oxidized glutathione (GSSG).
What are the official names of this protein?
Glutathione hydrolase 1, Gamma-glutamyltransferase 1, Gamma-glutamyltranspeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Note=Associated with the plasma membrane and cell wall.
Protein: LPXC_NEIG1
Sequence: MLQRTLAKSIGVTGVGLHSGERVALTLHPAPENSGISFRRTDLDGEMGEQIKLNPYLINDTRLSSTIVTDKGLRVGTIEHIMSALSAYGIDNALIELNAPEIPIMDGSSLPFIYLLQDAGVVDQKAQKRFLKILKPVEIKEAGKWVRFTPYDGFKVTLTIEFDHPVFNRSPPTFEIDFAGKSYIGEIARARTFGFMHEVEMMRAHNLGLGGNLNNAIVIGDTDVLNPEGLRYPDEFVRHKILDAIGDLYIVGHPIVGAFEGYKSGHAVNNALLRAVLADETAYEWVEFADSDDLPDAFHELNIRNCG
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: ATG3_PICAN
Sequence: MTGLYLRSTFSSLREYLTPISHKSTFTDTGEITPEEFVAAGDYLVYKFPTWQWSPAPESKKRDFLPNDKQFLVTRHVPSYVRAADYEHTEKEAEMMEEEDGWTSTNVDSVAPQRCNTEDERRHSIKYIEMTESGASSPEEGLAQHEGSGKHEINDIDELIDETAEESDLANDAGQGGIINDPKKRNYDLYITYSTSYRVPKMYLVGFNSNGVPLSPNEMFEDIASDYRQKTVTIEKAPFLSNTTSVSIHPCRHANVMRVLMKRAAHAAQAKKIRDKDLVTGVAKLGLADGKNADEEDDWENVEQGEEGIIRVDQYLVIFLKFIASVTPGIEYDYTMDAF
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_PROM1
Sequence: MIEIGKTIIKFPPLIEGILIKRYKRFLADIELDDGEVVTAHCANTGPMKGVLWPGGRVRLKYSPSPKRKLDWSWEQAEVPSHNEKKKCWVGINTSLPNKLIKHLIEANCLERQFGQISSIKPEVVYGLERKSRIDLLLYPSIQNEDSRKIFVEVKNTTWCDDSLALFPDTVTTRGQKHLKELMSVYPDSRAVLIPCISRSDMELFSPGEIADPEYGRLFREALTKGVEVIPCAFGFFIDHITWEGTRPLKSSR
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PRIO_NEOVI
Sequence: MVKSHIGSWLLVLFVATWSDIGFCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWGKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYKPVDQYSNQNNFVHDCVNITVKQHTVTTTTKGENFTETDMKIMERVVEQMCVTQYQRESEAYYQRGASAILFSPPPVILLISLLILLIVG
What is the function of this protein?
Its primary physiological function is unclear.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: ISPE_ACIBC
Sequence: MIRVPSPAKLNLFLHITGRRENGYHELQTIFQLIDLYDWMTFTPISEDEIQIEGLGEVQLEQNLIYRAAQILRPHAQNPCGLHIKIEKNIPMGAGLGGGSSNAATTLIVLNQLWQCGLTEEQLAQFGVKLGADVPIFIYGLNAWAEGIGEHLSFIDLDQKQFIVLKPDCFISTQLLFSQKTLTRDSKPTTFCAYQLEPSNFGNNFEPLARELYPEVEEAMQYLDQFGHAKLTGTGACVFAEVTDEMNVDDILKHAPCKAYLVHSLKESPLRHFKVAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TDCC_ECO7I
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y945_BACCN
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKAPFEAPEEQLETIVKELRTIANKTNPFTLHVGKVGSFAPVNNVIYFKVEKTPELTFLNEEMHKGFLTQEREYAFVPHLTIAQKLSDAEHADILGRLRMKDFYYEQTIDRFHLLYQLENETWNVHETFHLGKGSK
What are the official names of this protein?
Putative phosphoesterase Bcer98_0945.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: Y4DL_SINFN
Sequence: MAYKTEHITQQLRAAREAQKMSQRELSARSGLTQSHISQIERGTMEPGLGSLVDVARALDLEIVLAPKKLMPAIRNILDSASASSDVLTSDQRKLVGRLERWFAQHRGGFGSASEADTFKDSLALLRHLPLSAEEMDTFNEATARLDRSQADPPSRQELSRIAHAVRHLRNAAVHRDRDDAVPRSAYALDEEDDNA
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator y4dL.
Protein: M440_ARATH
Sequence: MPTILSSKPAFNSLFSYHLIGLISNKLVTLAPDYTGTKKTTWGARLHLQELRVQTKHRQIEPDIKNLPLQPIRYGSFRPVFHWIEKPCMLIGLCGLHSEVSFIANWPWGKPSEIGGCSIPCMLTGRGSELSYHIRASRRPLPGNRFHFQSFF
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00440/AtMg01140, ORF152a/ORF152b.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACLC_ASPOR
Sequence: MLPMAILPNGDRWCHGCRQRYLRSRFPIFSVDGSRTLPTCPYKWPNGQGDVAKFLQGIENRDLWEKEHGQIYRIWSGMKSEVVLTQPSHLQAVFRDSNKHSKAENNNSGYLMSELLGQCVGLVSRERWRTLRAVTEIPFQHDKMPSYLELIQRHTRHHFDRLLASGDLRQERIHPAQDLKMLPFWVVAEIFYGECDAEMKTELQQLCVLREDLFKRMIQGGIVRWQWSKYLPTATNRALAEFQRRWRAFNQRAYDRACQQQRILPIVLMIEAAREGSTSVEQIYQTIDEALFANLDVTTGGISWNLVFFAAHSDIQERVRQEVLSATDHDAYLLSSSTLLAACISESARLKPLAAFTVPQSAPTDRIIGGYNIPAGTNLVVDTYALNIRNGFWGADSQCYRPDRFLEHRATELRYQYWRFGFGPRQCMGRYVADLVIRTLLAHLVAHYELGWVEPDPGKNSTWQRDLESWITIPDLQLRCVQRRND
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Cytochrome P450 monooxygenase aclC, Aspirochlorine biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NU5M_LATCH
Sequence: MYTTLIFNSTLMTMFTILTAPILTTLNPIKPNKKWTELWVKTAVQLAFFTSLIPLFIYLDQGIETITTNWQWMNTNTFNINISFKFDQYSIVFIPIALYVTWSILEFANWYMHQDPKMNQFFKYLLLFLITMMILVTANNMFQLFIGWEGVGIMSFLLIGWWHGRANANTAALQAVIYNRVGDIGLTLSMVWFAINLNTWEMQQMFIMSYNTDMTIPLLGLTLAAAGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRLHPLMDNNKLILTTCLCLGALTTLFTAACALTQNDIKKIIAFSTSSQLGLMMVAIGLNQPQLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGLHNMLPTTSSCTMVSSMALTGMPFLAGFFSKDAIIESLNSSHLNAWALTTTLMATSFTAVYSLRIIYLVMMNYPRFQSLSPIDENYTKTRNPIKRLAWGSVIAGMMIFLNILPTKSQTMTMPTHMKTAAIMVTILGVLTAMELTKLTSTQLKITPNVNMHNSSNMLGYFPNIIHRLLPQTNLYLGQKMATHLTDQTWFEKIGPKGILALQIPTTKMINNSQQGLIKTYLTLFFLTTVLFTTMTMI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL32_HALOH
Sequence: MAVPKRRTSKARKRKRRTHWKLKSPNLVECPQCHELKLSHRVCPSCGYYKGREVVSK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ATPF_GRAFK
Sequence: MDLITPEIGLFFWQTIVFLILLFLMAKFAWKPILGSVRNREQSINDALASAEKARKEMQNLQSDNEQLLKEARAERDAILKEARELKEKVITDASDEAKVKADKIVADAKRSIELEKQSAMAELKNHVAELSVEIAEKIVRKELSGKNEQHQMIEKMIGDAKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PPK_CAMFO
Sequence: MIVTGNPVCAIALLLCLVFRASGEYELEMSSGGSNDGRSPSNDFGSCTDGKCTKRTTTTQESGISSGMWFGPRLGKRHKSNEKQQINPEIEMLVNALDQPGMRWTVITIPANEKRQPTQFTPRLGRGSEEKFIYSDATDRNEIDEDDPLFTPRLGRRVPWIPSPRLGRQSRSVSRKI
What is the function of this protein?
Pyrokinins mediate visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
PBAN-type neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMTC3_DROME
Sequence: MSTNPNPGIHQYAPSTLPREREREGATNSPQRNLLEFLCICVACIVCYYNSTQCGLVFDDISAIRDNKDLRPHTPLINVFLNDFWGTPMRKEQSHKSYRPLTVLTFRFNYLLHALEPFGYHLVNLLLHLSVCLLWRRVCRLLLRQCAASGSNAISAPSSSSVSQLNTCAFVASLLFAVHPVHTEAVTGVVGRAELLSSICFLAAFLSYAKSVGDSGCPRRTNWLTLFGCFGSCLLASMLCKEQGITIAGICVVYELFVVHQLRPLHLCHFVLRLFDERTEQQSPKLANPSGIRRWSSSTLWKRLSFLVGITLTLLVGRVYVMGSQLPIFTRFDNPASAADTPERQLTYGYLIYLNCWLLLCPSLLCCDWTMGTVPLLQGFTDSRNITTLLTFLALGAMVAKTCFTRNLALSRTLIMCLGWMVLPFLPASNLFFPVGFVVAERILYMPSMGYCLLVAYGFEQLQRRGSLSWQRFSQAALAILLLTHALKTHQRNLDWRTEYSLFMSGVHVNQRNAKLYNNVGHALENEGKFEEALLYFQQAVRIQTDDIGAHINVGRTFNNLKRYAEAEQAYVQAKALFPQAKPGVSYHARIAPNHLNVFINLANLIAKNQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVYEQALLYDNENADIYYNLGVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAILLQELGGEEARRVSRSRLYKVLENDDQNEKVYFNLGMLAMDESSFDEAEQFFKRAIHLKADFRSALFNLALLLADTKRPLDAVPFLNQLIRHHPSHVKGLILLGDIYINHMKDLDEAEKCYRSILHYDPHNTQGLHNLCVVFVERKRLAKAAACLQYAQRLAPAEDYIGRHLQIVLARLQKINKLPESAPERKLAYEDYDPLEFKLPQDRPTHKSRKRS
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.
What are the official names of this protein?
Protein O-mannosyl-transferase Tmtc3, Transmembrane and TPR repeat-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: CBIA_SYNC1
Sequence: MSCPRLVIAGTSSGAGKTSLTLGLTAALRRRGLKVQTFKVGPDFLDPTWLSLASERPCINLDGWMCGERYVRDRFATATADADIAIVEGVMGLFDGADPAAAAGSTAEIARWLDAPVLLVVNAHGMARSLAALVKGYAEFDPDLHLAGVIANRCGSTRHGDWLSEALCAAGMPPLTGTVIRDSLPPLPSRHLGLVTADRQHLTSEALNTLADAVERQLDMPRILDLAEKVPATPGVAATASSTEGRPVRIGMAFDEAFHFYYPDNLQALEDAGATLVRFSPMHDDTLPADLDALLLGGGYPEEYADTLETNQTMRQAVADFAAADRPIYAECGGLMYLSEGIELRDGSRHAMTGALPFATRMLATRKRLGYAEVRHLAHGPFGPAGTCLRGHEFHYSEAIAEPAAPGWQSAWQVSYRRSNKPVAEGYQRGRLFASYVHTHFASRPGAARAFVDFCRGES
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: M10L1_MOUSE
Sequence: MIDDLIYFSNDAVTSTVLLNVGQEVIAVVEENKVSNGLKAIRVEAVSDKWEDDSKNSSKGLSDSSPRVLIGCVTSMLEGAGYISQTTYFSLESVCEGFHPCKGDWVEAEYWIRPGTWSSEAISVKPLRYKRVDKVCISSLCGRNGVIEDSIFFSLDSLKLPEGYIPRRHDIVNAVVVESSQSCYIWRALCMTPVKRDATLGEAPQEPYGALLLKNKGDIEVTRMTSFGTLKEGESKSIVIWIENKGKFSRELVSCRLANWDKAHQFRFETQGRSKSCPGAAAGSVPEGENVNSLNHHREDKTDEIPESRLANSTEISPDGCACKEESREKGNTPEKQEPEPGGLIPPGEKTHIVVTCSAKNPGRCKELLLLCFSDFLIGRHLEVSVVSSEEALIAVREPFSWKKPKSSQTLVSAKTTVVVTTQKRNSRRQLPSFLPQYPIPDRLKKCVEQKIDILTFQPLLAELLNMSNYKEKFSTLLWLEEIHAEIELKEYNMSRVVLKRKGDLLVLEVPGLAESRPSLYAGDKLILKSQEYNGHVIEYIGYVMEIHEEDVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVIHLGVKVLFPEEIILQSPQVTGNWSLAQDTKNDGQSITNITRNDGQSMTKVTRNDSQSITNIIRNDGQSITNVTRNDGQPITKVTRNNSQSITNITRNDGQPITKNKKTVKDQTKHTTEERHVGTTDQPEKASSTAETMDEIQIPKARDKEFFNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVCLRLHESKVPKPAAMVRVNATCRFEETIIDAIKPYCRDGEDIWRASRFRIIITTCSSAGLFYQIGVRVGYFTHVFVDEAGQASEPECLIPLGLISDINGQIVLAGDPMQLGPVIKSRLAMAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLVTKLVKNYRSHSALLALPSRLFYHRELEVCADPKVVTSLLGWEKLPRKGFPLIFHGVRGNEAREGRSPSWFSPAEAVQVMRYCCLLARSVSSQVSSKDIGVITPYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIILGNPHVLVRDPCFGALLEYSVSNGVYTGCDLPPELQALQK
What is the function of this protein?
May act downstream of MEF2C during heart formation.  Acts as a cardiac-specific suppressor of cardiomyocyte hypertrophy and cell cycle progression, suggesting that it may suppress these processes through the regulation of CDKN1A.  Such results however require additional evidence.
What are the official names of this protein?
RNA helicase Mov10l1, Cardiac helicase activated by MEF2 protein, Cardiac-specific RNA helicase, Moloney leukemia virus 10-like protein 1 homolog, MOV10-like protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis (PubMed:20534472, PubMed:23166510). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: SUS1_CANAL
Sequence: MSTNNSTQQQDELDQIKSKIQDNLISSGNYDIINKQLKLQLYESGWYDKVSQIASRELMDHQQEVNSSNSNSSNSNKKNELTFDQLFAFVKPKAEELVPNEVKQDILNRITKYLDDIIQ
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: GL14_ARATH
Sequence: MEGLLQFLLAKIILLALASSFVYCYDPSPLQDYCVATNETNGVYVNGEFCKDPKRVTTNDFYTSGLNVPGNTIIGPGARNTVVDVERLPGLNTLGVDIARYDFAPGGLDPPHTHPRGSQIFLVMKGKLFVGFVSSNEYNYTLFTKVLYPGDVFVFPKGLIHFHANIGETNAVVISAGGSQDPGRIIIGDAVFGSKPLIDPKVLAKAFALDYNKVKYLQAVFS
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 1 member 4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: GSTK1_CAEEL
Sequence: MPKLPRIDFYFDVISPYSYIAFEVFQKLETQWKGVTIRYIPFFLGAVMKESGNRPPAMLPARSIMMMTDLKRTAKFWDIPLTPPPLFMEWIKKYRTTGAMKVLLVLQEQDKELMLRAAREMWVRLWSRSEKIFEDQDFVEVLKAVGVKNPEQIVEKSKDEKYIKILMENTNKGVDLMAYGAPWINVHTEDGSEHSFFGSDRFHLIADLLQQPQPLPDRLFGQKSKL
What are the official names of this protein?
Glutathione S-transferase kappa 1, GST class-kappa.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Kappa family.
Protein: SCA4_RICSM
Sequence: DTSEFDPLANKEYTEEQKQTEEQEQKEFLSQTTTPALEADDGFIVTSASFAQSTPSMSALSGNISPDSQTSDPITKAVRETIIQPQKDNLIEQILKDLAALTDRDLAEQKRKEIEEEKEKNKTLSTFFGNPANREFIDKALEKPELKKKLESIEIAGYNNVHNTFSAASGYPGGFKPVQWENHVSASDLRATVVKNDAGDELCTLNETTVKTKPFTLAKQDGTQVQISSYREIDFPIKLDKADGSMHLSMVALKADGTKPSKDKAVYFTAHYEEGPNGKPQLKEISSPKPLKFAGTGDDAIAYIEHGGEIYTLAVTRGKYKEMMKEVELNQGQSVDLSQAEDIIIGQGQSKEQPLITPQQTTSSSVEPPQYKQQVPPITPTNQPLQPETSQMPQSQQVNPNLLNTATALSGSMQDLLNYVNAGLTKEIDSNKQIDLIKEAATAILNNEKSDIAEKQANIIALAENTVNNKNLKPDAKVAGVNAVLETIKNDQNTPNLEKLKMLEATVAIILNSENLEPKQKQQMLEKAVDVGLSLKDDASRAVTIDGIKDVVIKTNLSTEDKGTMLIAVGDKVNVSELSNAEKQKSLGSVLKKGVEAQVLSPAQQQLIQQHLDKITAEQIKKDTIKKVNDILFDPLSNTELKTTNIQAITSNVLDGPATAKVKGEIIQEITNTVAGSSLEAQDKAAIIKGIGETIATHSDTSLSLPNKALIMASAEKGIAESQTNLPDRELMTKGLVDGIYEGKGGPEITKAVSSGIDNSNINDSEKEALKKAKDAASEAALDRDTQNLTEGLKGQNIEEHKPHDDIYNKAREVINAVNPVIEALEKSKEPVVSAEERIVQETSSILNNISKLAVEKVNNFRAMLSPNGNLKTLEEKKEESIKKVDELVKAFGTKSSTEEQQSFIKTNLIDDKTLSKEVRLQTIDKLLQEQKRAEAIENPSVKTEDVRVVSGKSKLKPISKDNPDIEKAKMVVGRDRVNIKGNIKIMGALMNARDIIQSENLNKSTPIKRE
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_ACHLI
Sequence: MRFKRVFLIVMDSLGVGASEDANQYFNEGVDDTKANTFGHIAESMDLRIPNLEKLGVGNIIPIKGTKSVELSSSYVTKIREKSLGKDTMTGHWEIMGLYVTTPFQTFTDTGFPKELLDELEERTGRKIIGNIAASGTEILKDLGEEHMRTGDLIVYTSADSVLQIAMHEEIIPIEEQYRISAIARDITMRPDWKVGRVITRPFLGTNKDNFKRTSNRKDYALKPSEETTLNFLSDANYDVIALGKINDIFDGYGINKYSKTVSNDDGMKQITEWAKKDFTGLCFLNLVDFDALYGHRRDPHGYGKAIMDMDSQLPELMANLNEDDLLILTADHGNDPTYVGTDHTREFVPMIAYSKSFKSGGSLPILNTFADLGSTISDNFKVKKTEHGDSFLSKLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAI2B_MOUSE
Sequence: MTTLNTGSARISIMNGSSVASTSPSVKCKEDQGLNGHEEKENPFAEYMWMENEEDFNRQVEEELQEQDFLDRCFQEMLDEEDQDWFIPARDLPQAVGHLQQQLNGLSVGDSHESEDILSKSNLNPDAKEFVPGVKY
What is the function of this protein?
Inhibits translation of capped and polyadenylated mRNAs by displacing PABPC1 from the poly(A) tail.
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 2B, PABP-interacting protein 2B, PAIP-2B, Poly(A)-binding protein-interacting protein 2B.
What is the protein family that this protein belongs to?
Belongs to the PAIP2 family.
Protein: BSDA_BACSU
Sequence: MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGVVLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAALMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDIPCVLVLSDEAGYPCGDTIKMVDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCECHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPKPAQQFLDLF
What is the function of this protein?
Could be a positive regulator of bsdBCD expression in response to salicylic acid.
What are the official names of this protein?
HTH-type transcriptional regulator BsdA, Bsd operon regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.