PharMolix/UniProtQA huggingface dataset:
Protein: ATPH_CUSRE
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit C, plastid, ATP synthase F0 sector subunit C, ATPase subunit III, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: RL21_ACIC1
Sequence: MYAIVRGGGRQHRVAVGDVIEINAAAKGATATVGATVELPAVLVVDGPSVTTGATALADITVTGEVVGHAKGPKIRILKYKNKTGYRRRVGHRQPLALVKVTHIGPRAAADRKTAPKRASAKAAADQTTAAQATAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: Y2757_MYCTA
Sequence: MTADEPRSDDSSGSAPQPAATPVPRPGPRPGPRPVPRPTSYPVGAHPPSDPHRFGRIDDDGTVWLVSASGERIVGSWQAGDPEAAFAHFGRRFDDLSTEIMLMDERLASGTGDARKIKAHAIALAETLPTACVLGDVDALADRLTSIRDRAEVIAAADRSRREEHRAAQTARKEALAAEAEELAANATQWKVAGDRLRAILDEWKTISGVDRKVDDALWKRYSTARDTFNRRRGSHFAELDRERSGVRQSKERLCERAEELSESTDWTATSAEFRKLLADWKAAGRASKDVDDALWRRFKAAQDSFFTARNAATAEKEAELRANADAKEALLAEAERLDTTNHEAARAALRSIAEKWDAIGKVSRERAAELERRLRAVEKKVREAGEADWSDPQARARAEQFRARAEQFEHQAEKAAAAGRTKEADEAKANAEQWRQWAEAAADALTRRP
What are the official names of this protein?
Uncharacterized protein MRA_2757.
Protein: DEOD_LACCB
Sequence: MSTHIDAPKGAIADVVLLPGDPLRAQYIAENFLDNAQRYNTVRNAFGFTGTFEGRRVSVQATGMGIPSISIYVNELIQDYGVKTLIRVGTAGGMGENVKVRDVVLAQGSSTDSSIILNTFGAGLYFAPLADFNLLREAANLADTSAIRYHVGNVLGEDRFYNDEMDRQKLIDYEVLATEMETPALYLLAAKYHVHALSILTVSNHLVTGEETSAQERQTSFNDMIGLALGVAKTVPDR
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: YQGF_PROMM
Sequence: MTATKPSPKSMLSLDLGKRRIGLAGCDPLGITVSPLPPLQRKSFERDLKVLQWHCTSRKVEGLVVGLPLDAKGLPTDQARHYERYGQRLARALKLPLALVNEHSSSWAAAERYNLQGDRSGQLDSAAAALLLEQWLREGPELKPVHVAAHPVSQVNSDSGS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1571_METJA
Sequence: MFKIYNIKSRIIRENMNNKLFDKTIEHVIKYLNENIFFEKYTRISGLLQNIESRIKIISLVIFLVGSVLSKHILTLIIFNSIALILAYLSNIPLLQYLKRVYVFIPIFAGIIAIPVMFNFMTPGKDVFVILNNPHISITYEGLIYAITFTLRVATCVSFAVLIPITTQWNKVTSAIHKLGVPEVVITITNLAYRYIFLLLNFVLDMMYSRKSRVVNKLGMVESWKEAGKAIGALFIKTYQMGEDXYYAMLSRGYNGEIKHIYREEIKIKDIAFLLFSIIITALLVLFDRGIL
What are the official names of this protein?
Uncharacterized protein MJ1571.
What is the protein family that this protein belongs to?
Belongs to the CbiQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CPFC1_BACAN
Sequence: MKKKIGLLVMAYGTPYKEEDIERYYTHIRRGRKPSPEMLEDLTERYRAIGGISPLATITLEQAKKLEKRLNEVQDEVEYHMYLGLKHIEPFIEDAVKEMHNDGIQDAIALVLAPHYSTFSVKSYVGRAQEEAEKLGNLTIHGIDSWYKEPKFIQYWVDAVKSIYSGMSDAEREKAVLIVSAHSLPEKIIAMGDPYPDQLNETADYIARGAEVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEKYGYTSFVYAPVGFVAEHLEVLYDNDFECKVVTDEIGAKYYRPEMPNASDAFIDCLTDVVVKKKESVM
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase 1.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFL12_YEAST
Sequence: MLLLVIPILQIALENLLLFRQNCLLVVGKYHELDRILSSPSLIRVSPLFSFRFYLVNHELFPIPYQHSLGVLYLLVPLPHSRVTCFSLYTICYRIVLIWAKKKKSLIISDTAKYILAWLRKVLL
What are the official names of this protein?
Putative uncharacterized protein YFL012W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIS7_PARP8
Sequence: MRLAEVVRNTSETQIRVKINLDGSGQQKLATGVPFLDHMLDQIARHGLIDLDIEAHGDTHIDDHHTVEDVGITLGQAIAKAVGDKKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGLNAHHQMETVFKAFGRALRMATELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_LEPIC
Sequence: MAETSNNKTSEEAKANEKKSQSETLEESKLENMNSEESTETTQTESMETAETETSLQTELESAKKEIESLKDSWARERAEFQNFKRRSAQEFVSIRKEAVKSLVSGFLNPIDNLERVGATQTNSEELKPFVDGVTMILKEFYSVLEKSNVIRFDPKGEPFDPMSMEALSSEEGDQYSEETVIDVYQPGYYYKENEDKFTLRPARVRIGKPKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OADB2_SALTY
Sequence: MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAGLALTALESLLAHHDAGQLAVIAAKLHCAPDVHAIKEALALALPSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTLNYFGLISFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPIMKALTSETERKIRMVQLRTVSKREKILFPVVLLMLVALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKFLQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSNKVGLESDAQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Oxaloacetate decarboxylase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_DEHMC
Sequence: MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANVMRAKSTRISTSTPVLDIVGIGGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSADVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKFVAPSRREIGIRTVFNILGPLTNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDKEIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALMVADKIDTIAEGISLAAEIIDNGLALNKLESLIKLSQSLASG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: DES_BACSU
Sequence: MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCHQSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFILGPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFEADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDEDNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA
What is the function of this protein?
Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids.  It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids.
What are the official names of this protein?
Fatty acid desaturase, Delta(5) acyl-lipid desaturase, Delta(5) desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECX_BACCZ
Sequence: MAVITKIEVQKRSKERFNIYIDKGQGEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIENALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQQEALHYHGNKYYEKYKKYDGWTFENKMKQALYRKGFSIDEIEIFLQMKREEG
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_VEREI
Sequence: MDRLLIRGGRRLHGEVPVSGAKNAALPQLCAALLSAEPVTLLNMPRLQDVSTMLRLLHHMGVGVERSDDGPLRIDAGALHTPEAPYELVKTMRASVLVLGPLLARRGAAKVSLPGGCAIGSRPVDQHIKGLTAMGADIVVEHGDMIARLSAGRRRLKGAHIATDMITVTGTENFLMAATLAEGETVLENAAQEPEIADLAEMLIAMGAQIEGHGSSRIRIQGVDRLHGCSHRVVADRIEAGTFLCAVAATGGDVLLRHGRADHLDAVIEKLRAAGADVQALADGIRVQSPGGAKLKAQGFRTTEYPGFPTDMQAQFMALDCIAQGTATVTETIFENRFMHVDELLRLGARIQVDGKVAVIEGQPRLSGATVMATDLRASACLVIAGLVAEGQTAVERIYHLDRGYDCMEAKLHGIGADIERVPA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STAAC
Sequence: MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKLSEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLGLARTRRQARQLVNHGHILVDGKRVDIPSYSVKPGQTISVREKSQKLNIIVESVEINNFVPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: LEXA_XANCI
Sequence: MDLTDTQQAILALIAERIDADGVPPSQTEIARAFGFKGIRAAQYHLEALEHAGAIRRVPGQARGIRLAGQGAQTRTAPVSEVARDDVLRLPVLGRVAAGLPIGADIGSDDFVVLDRVFFSPSPDYLLKVQGDSMRDEGIFNGDLIGVHRTRDARSGQIVVARIDEEITVKLLKIGKDRIRLLPRNPDYAPIEVLPDQDFAIEGLYCGLLRPNR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Has been shown to bind to the palindromic sequence 5'-CTG-N(8-12)-C-[TC]-G.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RHAB_LIGS1
Sequence: MKAYVAVDIGASSGRLMLGQLEDGKLKLQEMHRFKNGFEFKNNHDRWNIDYLIDEIFKGLEKIKESGYTEVSLGIDTWAVDYVLVGKDGKKLQDPISYRDKRTSNSINELTTEVSKEYIYKKTGIQFLNFNTLYQLFEEDKELLKKTDKIMMIPDYIGYILTGKAVTEITNASTTQMLSLREGLFDKNLLEKVNVSSDQFAKLVDAGTVLGNLKEDWYSKYELPKVNVVTVATHDTASAVIGTPCEGQHWAYLSSGTWSLIGTELNIPENGAKVFKENYTNEWGAYGTYRFLKNIMGLWMAQCVKKELNDQYSFSELAELAGEVEPFEQFINVNDQRFQNPGNMIQEIQTYCRETGQKVPETPGEIMMAIYSNLALFYANEISKLDDIMGYHIDTLNIVGGGSNVALMNQLTSTIANVDVYAGPSEATAIGNILVQMITAGDVLNVYLGRRIISNSFDIKHYTPEQGKYSKVLAEYQQFLNKERG
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: RSE1_NEUCR
Sequence: MATTSNMFLYSLTIQPPTAVTQALLGQFSGTKEQQILTASGSRLTLLQPDPRQGKVNTLLSHDIFGIVRAIASFRLAGSHKDYIILATDSGRITIIEYLPKTNKFQRIHLETFGKSGVRRVIPGQYLAADPKGRACLISALEKNKLVYVLNRNSQAELTISSPLEAHKPGVLVLSLVALDVGYANPVFAALELDYTDADQDPTGQAREEVETQLVYYELDLGLNHVVRKWSDTVDRTSSLLFQVPGGNDGPSGVLVCGEENVTYRHSNQEAFRVPIPRRSGATEDPQRKRVIVSGVMHKLKGSAGAFFFLLQTDDGDLFKVTIDMIEDSDGNPTGEVKRLKIKYFDTIPVATSLCILKSGFLFAASEFGNHHFYQFEKLGDDDEELEFSSDDFPTDPTASYNPVYFHPRPLENLVLVESIDSMNPQVDCKVANLTGEDAPQIYSVCGNGARSTFRMLKHGLEVSEIVASELPGTPSAVWTTKLTKYDQYDAYIVLSFTNGTLVLSIGETVEEVSDSGFLTTAPTLAVQQMGEDGLIQVHPKGIRHIVQGRVNEWPAPQHRSIVAATANENQVVIALSSGEIVYFEMDSDGSLAEYDEKKEMSGTVTSLSVGQVPEGLKRSSFLAVGCDDCTVRILSLDPDSTLEMKSIQALTAAPSALSIMSMEDSFGGSTLYLHIGLHSGVYLRTVLDEVTGELTDTRQKFLGPKPTRLFQVSVQDQPCVLALSSRPWLGYTDPLTKGFMMTPLSYTELEYGWNFSSEQCLEGMVGIHANYLRIFSIEKLGDNMIQKSIPLTYTPKHLVKHPEQPYFYTIESDNNTLPPELRAKLLEQQSNGDATVLPPEDFGYPRAKGRWASCISIIDPISEEPRVLQRIDLDNNEAAVSAAIVPFASQEGESFLVVGTGKDMVLDPRQFTEGYIHVYRFHEDGRDLEFIHKTRVEEPPLALIPFQGRLLAGVGKTLRIYDLGLKQLLRKAQADVTPTLIVSLQSQGNRIIVGDLQQGITYVVYKAEGNRLIPFADDTLNRWTTCTTMVDYESVAGGDKFGNIYIVRCPERVSQETDEPGSEIHLMHARNYLHGTPNRLSLQVHFYTQDLPTSICKTSLVVGGQDVLLWSGLQGTVGVFIPFVSREDVDFFQNLENHMRAEDPPLAGRDHLIYRGYYTPVKGVIDGDLCERFSLLPNDKKQMIAGELDRSVREIERKISDIRTRSAF
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor rse1, mRNA-splicing protein 5.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HLX_RAT
Sequence: MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFALDPAAVKKPSFCIADILHAGVGEPGPAAEGLVGASAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHQHLPQQPPTQQQQPQQQPPPPPRAGSLQPPTSGTRVVPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPTGVHLAGLQPSAGQFFASLDPISEASAILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGEREERSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSASGSSFSFSSSSSLGSSNGSAGSASSLGSNCSELLPSHQPSVTSGPQSPEIAQVPLAGL
What is the function of this protein?
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression.  Involved in embryogenesis and hematopoiesis (By similarity).
What are the official names of this protein?
H2.0-like homeobox protein, Homeobox protein HLX1.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHS5_SOYBN
Sequence: MVSVEEIRQAQRAEGPATVMAIGTATPPNCVDQSTYPDYYFRITNSEHMTELKEKFKRMCDKSMIKKRYMYLNEEILKENPSVCAYMAPSLDARQDMVVMEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPLPVEKPLFQLVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPEKMEATRHVLSEYGNMSSACVLFILDQMRKKSIENGLGTTGEGLDWGVLFGFGPGLTVETVVLRSVTV
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 5, Naringenin-chalcone synthase 5.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RDRP_ROTGI
Sequence: MDSFQFFEWLLRDIERNLLYTSLVYTNPKIAIVRYEPSENAKLWRSKELNTDSPNELLLTLKKTLDECSTLDEKIETLLRIRYFTVYVGDKSDKRNIIRSWLSTTINRLNVEEYASIQEIELQAKQWRAENAKSLRPYHYNIPINEYLRDNEIEVLDTGDNRWKSDTLQGLLPNFYHRTHTLIGAILFAVTSRLEIYSYEQKKALRYLLRTIEKCYNEGYLEMSRDRKWSHTLPELRTLTFRLYNSKVIHAACAMISLVHANPIDYEFLCQVVAVYQIIPANAAKLLSTPMTLYVGVATFSSNQVASTGNASECAPLQIENNIYVSEAQKKEWAESFKSDPLNKSRMLKLMNENLNTTLDKFSLIFNCFSSTFHVGHRIDNAQDAITDQVTATYTSNVNREMYDSYYYKLKQMLKEEIVQYVEDHVAKQYKDVTAESLSALANSSNGFSKEVKFIDRNIKTTKKILHLDNDLITNDYSDLSKALSHGIPMGTRNVPARQTRGIFILPWQVAAVQHTIAESLYKRAKKGAYQGSFAEAYTAKTASLTYGVLAEDTSKATKIILYTDVSQWDASQHNTEPYRSAWINAIREARAELKWRYDDEPKVLEMNVLDSMIKIQEYLLNSNLVVASPGSQRPTKIIRYHGVASGEKTTKIGNSFANVALIETVLDFAKTDIPDLEISHLRVDGDDNVVSINTSCTIDRLQRIIKEKYSSLNARVKALASYTGLEMAKRFIICGKIFERGAIPIFTAERPYGTDVSIQSMCGSSIYSSAVNAYRGFGDAYFSFMQDVLVPPSASTRITGRLRVLMSPVTLYATGPLSFEITPQGLGGRCRFFTQSAKLFTLFKMLTQTAAVSITPDEIKKYAETVQFKKRTEVMIASMQRKLLVPAKALARIIVDKEQQKTLGVPNVQSQKNRSQVSKAIEILGVPERNDIVAKGYYPEELYSLIISHSVVVYTSHSTPISIYRVNCEPVELLRSQLGIRIADSKPIAKPTNHLYDIVSGLSPIKISPSDLLTQAKKYDLSTYKGKRDYLSDLGLVGNTLKTYLASKMLFRDLLMSKYDDLYSTPGFGATQLTTIPLDVTSAEKVFSIRLGLPPHLYEVVMLLLLYEYIHYVFSCKRTFTAQMHAISQEQSAVITKNIILMLDNIQLDQVSFSDDAW
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsDNA formation.  To do so, the polymerase specifically recognizes conserved 3' sequence(s) in plus-strand RNA templates.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: G6PI_BEII9
Sequence: MNRDEVAKTFAALKAHREASQETIADLFRVDPNRFENFHIKLDDVLFDYSKHRVTRTTLDLLFALARAAGVEDRRSQLFDGAAVNITEHRPALHMALRKLDGAPVLAEGKDVMPEVLAERQKIFTFAEAIRKGTIKAANGERFTDIVNIGIGGSDLGPRMVVTALAPFVADHLTMHFVSNVDGADLGDTLKKLPLATTLFIVCSKTFTTLETMTNAQTAREAVAEKLGEAAVADHFCAVSTQLDKIAAFGIKSDRVFGFWDWVGGRYSVWSAIGLSVVIAIGAEKFEKFLLGGQDIDQHFQTAPLESNVPVIMALLEIWYRDLWDYATRAVIPYDERMHRFSAYLQQLEMESNGKSVQLSGAPVTESTSPVVWGEPGTNGQHAFFQMLHQGTEIVPIDFLVAAQPSGADAKHHQLLVANCLAQSQALMQGRSLEDVKTLLTAQGLDTAAVNTLAPHKVFPGNRPSSTFLYKRLSPRVLGQLIALYEHKVFVEGVIWNVDSFDQWGVELGKELANKLTPIIRDSEASLEGLDGSTAGLIGEIRKHKKG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_VIBC1
Sequence: MSRKKKSRNPGASGAPEFVVTRNRTESDVEGRLRKRAKKRKGLKTGSRNSDAEEQKRQAAAQKRDPRLGSKKKIPLIVEPVKKQTKQERRLSAEQELEMLENDAQLNVLLDRIEAGENLGTGLQKYVDEKLDRIEKLMDQLGLLEPEEDEDFTAPAVKGSRNDDDLLADFDDINFDDYKG
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: MCM6_CAEEL
Sequence: MDNIIGGQAQQVEDTDGTRVQNEFSKFLKSFKDQKNEFIYKSAMKELVQPEKNTIFINMQHLYKFSNNLATTIELQYYRVYPFMCEALHLATLDACDESERQQMFKKQLYVSLFNLDAKTKVRELSADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAVEETDYLDLWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKKSRDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRAISEHTERDSVYKIDDIKKYIAFARCFKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEHVEKAAELLNKSIVRVEQPDIALDDDDFDNNIMVVEADKENQRGDDSMDHDGEKENAPKIDIAKLKISFKEYKQLSDVLVLHMRSDEDNQGEDEYDGVKQSALVEWYLSTIEADLETEEDFNVQKTICERVIHRLIHQDHVLLEVEQGEDPTLCVHPNYVIADE
What is the function of this protein?
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity).
What are the official names of this protein?
DNA replication licensing factor mcm-6.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_SHEPA
Sequence: MANSKSAKKRALQSEKRRQHNASRSSMLRTYVKKVIAAINAGDHATATAAFAVAQPIVDRMATKGLIHKNKAARYKSRLNAKIKALVA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MERB_CLOBU
Sequence: MKTEIQEIVTRLDQQSNKGEGGESMKWLFRPLLQMLAGGESVTIEDMATTTGKPVEEVKKVLQSLPSVEIDEQGRVVGLGLTLIPTPHHFTVDGKQLYAWCALDTLIFPALIGRSVNIESPCHSTGEPIRLNVEPDHIVSVEPSTAVVSIVTPDDMSSIRTAFCNEVHFFSSPNAAEDWLDQHPGGKVLSVEDAFELGRLMGTRYEESRPANGSCCHI
What is the function of this protein?
Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate.  One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
What are the official names of this protein?
Alkylmercury lyase, Organomercurial lyase.
What is the protein family that this protein belongs to?
Belongs to the MerB family.
Protein: CALM1_ORYSJ
Sequence: MADQLTDDQIAEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-1, CaM-1.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.