PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_POPAL
Sequence: MRINPTTSGPGVSALEKKNLGHIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVSQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDDLGPVDTGTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPQIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGELDSLPEQAFYLVGNIDEATAKATNLEMENNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CPDA_ECOLI
Sequence: MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
What is the function of this protein?
Hydrolyzes cAMP to 5'-AMP.  Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.  Specific for cAMP.
What are the official names of this protein?
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, 3',5'-cyclic AMP phosphodiesterase, cAMP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: LEUD_SALPA
Sequence: MAEKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPEFVLNFPEYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDEQVDELFTLVKANPGIKFEVDLEAQVVKAGDKTYSFKIDDFRRHCMLNGLDSIGLTLQHEDAIAEYENKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SCXND_MESEU
Sequence: TGVESARDAYIAKPHNCVYECFDAFSSYCNDLCTENGAKSGYCQIAGKYGNGCWCIELPDNVPIRIPGKCHRR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Sodium channel neurotoxin MeuNaTxalpha-13.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHLL_SYNP6
Sequence: MKLSVYGKGGIGKSTTSCNISVALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQAKDYHYEDVWPEDVIYRGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYSDYCLIITDNGFDALFAANRIAASVREKARTHTLRLAGLIGNRTSKRDLIDKYIEAVPMPVLEVLPLIEDIRISRVKGKTVFEMAETEPSLLTVCDYYLNIADQILARPEGVVPKDAADRDLFSLLSDFYLNPPKQTTEAIAPEALLV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RL15_SULAC
Sequence: MVVRKEKKSRKYRGYRTHGWGTKGQHRDRGAQGGRQIGMHKEKWSWTVKFGEGWYGKHGFRNPTSKLVNAIGLRKLQEYIDNDKIKIEEENGKKVVDLAKYGYDKLLGGGNLRLPLVIKVAKATEKAKERVKEIGGEIILTSSE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PYRB_LATSS
Sequence: MTNQTAIVSVEQLTNSSVLNLIERAEAFKQGATCELTRPVYAMNLFFENSTRTKTSFEMAERKLGLSVMSFEAETSSVSKGETLSDTLKTVQAIGVDFVAVRHPQNYYYDDLLADPAFHLALANGGDGSGQHPSQCLLDMMTIHEEFGHFDGLKVVICGDLRHSRVAKSNMQLLKRLGAQLYFAGPEEWFTAEFNDYGQHVALDSILDQVDVVMLLRIQHERFDSAETMTDEAFHVKYGLTAQRAAQLKASTIWLHPAPVNRDVEIADELVEAPQSRIFKQMHNGVFMRMAMIEYLLKQKNLIKD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PROB_IDILO
Sequence: MKAPSWRRAVLKVGSALIAPDETGVSTKYLLPIARFINECRERGQEVVLVSSGSVAAGRKHFNFEHKKVPVAVRKAMSAVGQNEMMGYWSRFFDSPCAQLLMTHSDLRDRARYVSIKNTLNRLLEHDILPVVNENDALATDEMKVGDNDNLSAMIATLVDADALFICSDIDGLYDSDPNLNPDAKKIPVVEQIDESIYSLAGGSVSSVGTGGMRTKVEAAEKATSHGIDTYIVNGRKGETFESLLQGDIPGTLFRRQSDPISNKKHWLRHTLVAQGEILVDEGAEKALIENGASLLSSGIVDVQGDFDRGDAVLVRSANDTDAIAKGICQYSAHELMHIKGQQTEDIAEKFGYSPITEVIHRDDLMILEDS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_PSEP1
Sequence: MSEDLYEDDLDTQGSSGPRHPMAERFRGYLPVVVDVETGGFNSATDALLEIAAVTIGMDEKGFLFPEHTYFHRVEPFEGANIEPAALEFTGIKLDHPLRMAVSEESAMTDIFRGVRKALKANGCKRAILVGHNSSFDLGFLNAAVARNDLKRNPFHPFSSFDTATLAGLAYGQTVLARACQSADIDFDGREAHSARYDTEKTAELFCGIVNRWKEMGGWRDFND
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: CST1_CAEBR
Sequence: MPPSTDSSRRNSEEGFSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHKESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKNSDLWIVMEYCGAGSISDIMRARRKPLSEKEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRCCLIKKPEERKTALRLCEHTFIENAPGCDVLQAMILDAQEKVLLGQAPVAVAGADATLLSEGMSTMIDGGDATLVQYKDNYVTAQSLRSQMESLKIGGEIPKSAYGSSRNNGSPRVQPPGHTASACDPSNNPPFAEEGTGPNFQIGTSESSYKDASYNMMNTEAEYENRFQRAVCDGDFEFLRNITLDELIRRKESLDSEMEEEIRELQRRYKTKRQPILDVIEIKKRLN
What is the function of this protein?
Serine/threonine-protein kinase which extends lifespan and delays tissue aging, probably by activating daf-16.
What are the official names of this protein?
Serine/threonine-protein kinase cst-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: EX7S_CLOAB
Sequence: MPSKKESYESMIKELEKIVSSMENEELPLEEAMKNYEDGVKLCDKLYKILNKAEGKIKLLTENGEEEFKKAGDSYEQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_TOLAT
Sequence: MTKSDLIERLSSSQQHLAAKDVEAAVREILECMAATLESGNRIEIRGFGSFSLHYRAPRVGRNPKTGEKVELLAKSVPHFKPGKELRERVNSL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: IL1A_MOUSE
Sequence: MAKVPDLFEDLKNCYSENEDYSSAIDHLSLNQKSFYDASYGSLHETCTDQFVSLRTSETSKMSNFTFKESRVTVSATSSNGKILKKRRLSFSETFTEDDLQSITHDLEETIQPRSAPYTYQSDLRYKLMKLVRQKFVMNDSLNQTIYQDVDKHYLSTTWLNDLQQEVKFDMYAYSSGGDDSKYPVTLKISDSQLFVSAQGEDQPVLLKELPETPKLITGSETDLIFFWKSINSKNYFTSAAYPELFIATKEQSRVHLARGLPSMTDFQIS
What is the function of this protein?
Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems (PubMed:16256210).  After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex.  Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4.  In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways (PubMed:1386364).  Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage.  In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity (By similarity).
What are the official names of this protein?
Interleukin-1 alpha, IL-1 alpha.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. Recruited to DNA damage sites and secreted after genotoxic stress.
Protein: CLIC6_HUMAN
Sequence: MAEAAEPEGVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGASPGRGAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKVKLTALGCSRIAIKKYLRAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK
What is the function of this protein?
May insert into membranes and form chloride ion channels.  May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).
What are the official names of this protein?
Chloride intracellular channel protein 6, Parchorin.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity).
Protein: CYSH_BACHK
Sequence: MLTYETWEENDISFSEEDETKGALSVLSWAYKEYENEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQAKLHGNKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_NEIPH
Sequence: SIMKMDGSQQEENLDVISTGSLGVDLALGVGGLPRGRVVEIFGPESSGKTTLCLEAIAQCQKTGGICAFIDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGVDMVVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGHIKRTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGQIKKGDDVIGNETKVKVIKNKVAPPFRQAEFDILYGEGVSWEGELIDLGVKYDIVEKSGAWYSYNGSK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_NEIMU
Sequence: KTSTRTRCAFEVAARDQGAGVTYLEPSASQIRHKESIKDTARVLGRMYDGIEYRGFGQDVVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMANSLLVLGAKLGMDVRIGAPKTLWPSENIVARARAVAEETGGKILLTENAEEAVKGVDFIHTDVWVSMGEPKEAWQERIDLLKDYRVTPELMAVSGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTEEVFESSASIVFDQA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLNK_RAT
Sequence: MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMDKIKKLKVKGPPSVPRRDYALDNPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEETGDDSYEPPPAEQQTRVVHPALPFTRGEYVDNRSSQRHSPPFSKTLPSKPSWPSAKARLASTLPAPNSLQKPQVPPKPKDLLEDEADYVVPVEDNDENYIHPRESSPLPAEKAPTVNRSTKPNSSSKHVSPPGTVAGRNSGVWDSKSSLPAAPSPLPRAGKKTATPLKTTPVPSLQNASNVCEEKPVPAERHRGSSHRQDTVQSPVFPPTQKPVLQKPVPLPRFTEGGSPAADGPVPSFPFNSTFADQEAELHGKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVAFFNKRVYNIPVRFIEATKQYALGKKKNGEEYFGSVVEIIKNHQHNPLVLIDSQNNTKDSTRLKYAVKVS
What is the function of this protein?
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development.  Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK.  Modulates AP1 activation.  Important for the activation of NF-kappa-B and NFAT.  Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes.  However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling.  May be required for the RAC1-JNK pathway.  Plays a critical role in orchestrating the pro-B cell to pre-B cell transition.  May play an important role in BCR-induced B-cell apoptosis (By similarity).
What are the official names of this protein?
B-cell linker protein, Cytoplasmic adapter protein.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=BCR activation results in the translocation to membrane fraction.
Protein: GLPQ_TREPA
Sequence: MRGTYCVTLWGGVFAALVAGCASERMIVAYRGAAGYVPEHTFASKVLAFAQGADYLQQDVVLSKDNQLIVAQSHILDNMTDVAEKFPRRQRADGHFYVIDFTVEELSLLRATNSFYTRGKRHTPVYGQRFPLWKPGFRLHTFEEELQFIRGLEQTTGKKIGIYSEIKVPWFHHQEGKDIAALTLALLKKYGYQSRSDLVYVQTYDFNELKRIKRELLPKYEMNVKLIQRVAYTDQRETQEKDSRGKWINYNYNWMFEPGGMQKIAKYADGVGPDWRMLIENEWSKVGAVRLSPMVSAIQDAKLECHVHTVRKETLPSYARTMDEMFSILFKQTGANVVLTDFPDLGVKFLGKPARY
What is the function of this protein?
Binds human IgA, IgD and the Fc portion of IgG but not IgM, which may contribute to evasion of the human immune system.
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase, Glycerophosphoryl diester phosphodiesterase, Gpd.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side. Note=Has also been identified in cell outer membrane, but this may be incorrect (PubMed:9826352, PubMed:9317025).
Protein: DHTM_METME
Sequence: MARDPKHDILFEPIQIGPKTLRNRFYQVPHCIGAGSDKPGFQSAHRSVKAEGGWAALNTEYCSINPESDDTHRLSARIWDEGDVRNLKAMTDEVHKYGALAGVELWYGGAHAPNMESRATPRGPSQYASEFETLSYCKEMDLSDIAQVQQFYVDAAKRSRDAGFDIVYVYGAHSYLPLQFLNPYYNKRTDKYGGSLENRARFWLETLEKVKHAVGSDCAIATRFGVDTVYGPGQIEAEVDGQKFVEMADSLVDMWDITIGDIAEWGEDAGPSRFYQQGHTIPWVKLVKQVSKKPVLGVGRYTDPEKMIEIVTKGYADIIGCARPSIADPFLPQKVEQGRYDDIRVCIGCNVCISRWEIGGPPMICTQNATAGEEYRRGWHPEKFRQTKNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPGLGEWSYHRDYRETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGARWNTDGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKIGKRVVILNADTYFMAPSLAEKLATAGHEVTIVSGVHLANYMHFTLEYPNMMRRLHELHVEELGDHFCSRIEPGRMEIYNIWGDGSKRTYRGPGVSPRDANTSHRWIEFDSLVLVTGRHSECTLWNELKARESEWAENDIKGIYLIGDAEAPRLIADATFTGHRVAREIEEANPQIAIPYKRETIAWGTPHMPGGNFKIEYKV
What are the official names of this protein?
Trimethylamine dehydrogenase, TMADh.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: CRP1_YEAS2
Sequence: MSSELMFNYTFSWPAGPKDVILTGTFDDWRGTLPLVKTAKGNFEITMPVKLANKDDTFQFKFIVDGVWCVSDSYKKEHVSEGIENNFLQITDLVETQEVAGASRIPEAGGLLCGKPPRSAGPPSTSNRKKNKRNNKKRRSKLKKKSTKNNKNSNESLDDNEEEDGVTGTTTEDVTGTSREETPLAEPTNVSKEAPGNFHILPIDQSADTTQSNGIIGGPGPVLVPNPGEIKEFTEIRDVDARELNERLNKKEEVPEPVAGPIVESSVTEKSPALPQADDPIVETKEMAHNVQELTPQVEAVTPLINEPEPLPTPEAQISIPESSKVEPVEGSLQSKLVEKRESTEGVLDGSKKVENKAKKDEEVFTLDPIVNKAPKLPLTDEQTAEGRKSPAVSEEKEKKKKQEKGSKEVKRSETSKEKKPSAKEVKKQTVKASKKQTASPLSSSTEEPKKKKTGFFGKLKKLFK
What is the function of this protein?
Cruciform DNA-binding protein which exerts an enhancing effect on the cleavage of cruciform DNA (X-DNA) by endonuclease VII from bacteriophage T4.
What are the official names of this protein?
Cruciform DNA-recognizing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRP1/MDG1 family.
Protein: KAE1_CANAL
Sequence: MVVDLDKYLKPGKDHYLALGLEGSANKLGVGVIKHNKGPLSSTNRAEVLSNIRDTYITPPGEGFLPRDTARHHRNWVVRIIKQALATAKIAGKDIDVICFTQGPGMGAPLQSVVIAARTLAQLWNIPIVGVNHCVGHIEMGREITGAENPVVLYVSGGNTQVIAYSKQRYRIFGETLDIAIGNCLDRFARTLKIPNEPAPGYNIEQMAKKGKHLVPLPYTVKGMDLSMSGILAAIDSIAKEMFGKQQKKLIDEESGEPITAEDLCFSLQETLFSMLVEITERALAHVDSNQVLIVGGVGSNQRLQEMMKLMIQDRKNGQIYATDERFCIDNGIMIAHAGLLSYRTGQTNQLNNTVCTQRFRTDEVFVKWRDD
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SEPS_META3
Sequence: MFDTKKVLELANKDFEKAWITTKDLIKDAPINKKYPRIKPSFGKTNPVMDTIEQLRQAYLRMGFEEYINPVIVDEKDIYKQFGPEAMAVLDRCFYLAGLPRPDIGLSNDKIEQIEKLGIKIDSNEKKENLRKTLHLYKKGVLEGDDLVYEIANSLGLSNEMGLKILEEVFPEFKNLKAESLPLTLRSHMTSGWFITISEMMGKKPLPYALFSIDRCFRREQKEDKSHLMTYHSASCVLVGEDITLDDGKAIAEGLLSQFGFTDFQFRPDEKKSKYYTPETQTEVYAYHPKLKEWLEVATFGIYSPIALSKYNISVPVMNLGLGVERLAMINHNYEDVRKMVYPQFYEQTLSDRDIAYSIKVDKVPVLDELKDLTGELIELCVKNKDKQSPCEVFIEKKIKFYNTTKTIKITLFEKEEGKNLLGPSILNKIFVHNGNIFGVPESFDNVKEEFVKVLSEAKNKGAPTNLTYIDTICYKITSKIEEALISNTKKLKIRAPIVRSLSDVNLKIDELALKQIMGNNKVIDIRGPVFLNVKCEIND
What is the function of this protein?
Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
What are the official names of this protein?
O-phosphoserine--tRNA(Cys) ligase, O-phosphoserine--tRNA ligase, Non-canonical O-phosphoseryl-tRNA(Cys) synthetase, O-phosphoseryl-tRNA(Cys) synthetase, SepRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
Protein: LMOD2_RAT
Sequence: MSTFGYRRGLSKYESIDEDELLASLTAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKLAEEDKEESEEELIFTESNSEVSEEVCTEEEEESTEEEEEEEEEDSEEEEVTTEVTKHINGTVSHNGVNPDNSKPKTFKSQIENINLTNGNSGGTQRNTESPAAIHPCGNPTVIEDALEKIKNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIAEMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGATLRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPPHMLPPPPPPPAPPLPGKKLITRNIAEVIKQQESAQRALQNGQRKKKGKKVKKQPNNILKEIKNSLRSVQEKKMEESSRPSTPQRSAHENLMEAIRGSSIRQLRRVEVPEALR
What is the function of this protein?
Mediates nucleation of actin filaments and thereby promotes actin polymerization (PubMed:18403713).  Plays a role in the regulation of actin filament length (By similarity).  Required for normal sarcomere organization in the heart, and for normal heart function (PubMed:18403713).
What are the official names of this protein?
Leiomodin-2, Cardiac leiomodin, C-LMOD, Leiomodin.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton. Note=Colocalizes with actin filaments in sarcomeres. Detected close to the M line.
Protein: PIMT_STAMF
Sequence: MRSRFENERRRVIDYLRRIGIIRSDKVYRALLSVPREEFVPPQYREYAYIDEPLPIGFGQTISAIHMVAIMTEELDPEPGNIVLEIGTGSGYQAAVLAEIVAKQDPNRRGHVYTVERIPELAEFAKKNLERTGYIEYVTVIVGDGTKGYPEKAPYDRIIVTAAAPEVPKPLLKQLRVGGKLVIPVGDRFVQRLLSVKRVGEHEYVTKHGIECMFVPLIGEYGWKD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.