PharMolix/UniProtQA huggingface dataset:
Protein: AOX1_AERPE
Sequence: MVSRLRGFLAWVYRWITTTDHKDIGLLYLVTSIAFLLIAGSLALLFRVQLAIPKSNFLTGDAYYEAVTVHGLIMLLWFASPFAFGLANYIVPLQIGARDLAFPRLNALSYWLYLLSGLVLLASFFTESGAPNVGWTLYAPLTARIYTPGIGLDLAALAIFLFSLSVTLGTINFLVTIAAMRAPGIGWFKMPMFTWSILFTVILMLWAFPPLMVGGALLLLDRNLGTEFFLNPAGGALLWDHLFWFFGHPEVYILLFPALGAMADVISTFSGKPIYAKRYILTAFLIATIISFVVWMHHMFITGTNIYTRLFYSITTILISIPFEMAVMSFIFTLYKGRLVYTVPMLFAVGALLNFIIGGSTGVYLGSIAIDRGFRGTYWVVAHFHYILVGTVTLGLIAGLYYWWPKITGRTYSERLGKIHFALAMLGVALTFLPQFALMDMPRRYFTYDIPEWVPLNQLSTLGAFIFGGSMAIGLVNFLYSLVKGGSAAPNPWNSWTLEWFTNSPPPKHNFDGVPVVRKDNTVVFVSEEALSKYGKDAIVEGRVDVSNVPLSGGQSHSSHGLTHHGTTDPLVLAAGLTLALFGLFVSKPLSYLGAIVFLLSLARWLWKDVKNVFAEELPGYVEHWPFPKDKIRSAMWVFIASEVATFGSIFSAYFFIRFNPVGKFLTEAWPPGYLVHDVNVGLINTIILFTGTMLFTLAYLGVKRDNYLITLSGLLGTLFMAIYFLTVKYFEWKELLIAGLGLDAGMYMQAYYVTTGAHALHVILGVLATTYLLVKLFNGNLRGRQALSEVLAVGIYWGIVEIVWTLVFPLYYLV
What are the official names of this protein?
Heme-copper oxidase subunit I+III.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHEJ1_MOUSE
Sequence: MEELEQDLLLQPWAWLQLAENSLLAKVSITKHGYALLISDLQQVWHEQVDTSVVSQRAKELNKRLTAPPAALLCHLDEALRPLFKDSAHPSKATFSCDRGEEGLILRVQSELSGLPFSWHFHCIPASSSLVSQHLIHPLMGVSLALQSHVRELAALLRMKDLEIQAYQESGAVLSRSRLKTEPFEENSFLEQFMAEKLPEACAVGDGKPFAMSLQSLYVAVTKQQIQARQAHKDSGETQASSSTSPRGTDNQPEEPVSLSSTLSEPEYEPVAASGPMHRARLVKSKRKKPRGLFS
What is the function of this protein?
DNA repair protein involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination (PubMed:17360556, PubMed:27601299, PubMed:27798842, PubMed:27601633, PubMed:27830975, PubMed:28051062, PubMed:29077092, PubMed:30017584).  Plays a key role in NHEJ by promoting the ligation of various mismatched and non-cohesive ends (PubMed:17360556).  Interacts with POLL (DNA polymerase lambda); promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL (By similarity).  May act in concert with XRCC5-XRCC6 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are non-complementary or partially complementary (PubMed:17360556).  Associates with XRCC4 to form alternating helical filaments that bridge DNA and act like a bandage, holding together the broken DNA until it is repaired (By similarity).  The XRCC4-NHEJ1/XLF subcomplex binds to the DNA fragments of a DSB in a highly diffusive manner and robustly bridges two independent DNA molecules, holding the broken DNA fragments in close proximity to one other (By similarity).  The mobility of the bridges ensures that the ends remain accessible for further processing by other repair factors (By similarity).  Binds DNA in a length-dependent manner (By similarity).
What are the official names of this protein?
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XLF subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to site of double-strand breaks; recruitment is dependent on XRCC5-XRCC6 (Ku) heterodimer.
Protein: MTMC1_METMA
Sequence: MANQEIFDKLTNAIVTQDIAGCAKLTQEALDAGISPLDIITKGLSPGMKIIGDKFEAAEIFLPQIMMSGKAMSSAMEILTPELEKTKVEGEEGTGLAITFVAEGDIHDIGHRLVTTMLGANGFDILDLGVDVLNETVIEEAAKRKGQKIILVGSALMTTSMLGQKDLMDRLREENLRDSVKCMFGGAPVSDKWIDEIGADATAENAAEAAKVALNIMK
What is the function of this protein?
Acts as a methyl group carrier between MtmB and MtbA.
What are the official names of this protein?
Monomethylamine corrinoid protein 1, MMCP 1.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: MED6_ASPOR
Sequence: MASAQDGSMEEILWRSPAHVQMMGGFLHSNNILFYFAESPFFDATSNNASLAIQANYNETLRHFVETREAFEGRLKTMQGLEFVVAYDPLQAAAQTETSFAHEPSNIWVIRKQTRRKRAGLEDEVVVLSTYFVVGDCIYMAPSVASVVGNRLLSAVTSLTSLLKTASSLPSFTPSHGHTYLPPAPKPTDSSQPGAQSQQSKENTPMPDADSTKALLVGPQTANAGAILQDTRTFAESFSLLARYGEEFMDENPLVGEPGSFILSKSGDTDRGAASKQPSNVNRPGSIPGKVGTPQVKVDTPGKTPEKGATPSASDDSKIRKKKAKIGN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 6, Mediator complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SON1_ARATH
Sequence: MALPWELEEDILSRLPPISLVRFRTVSKHWNSLFNDKTFINNHLSRSRPEFIILTNSKIYSVDIIDHNNIDPTIRLHEIPTYDIHSRGTDLNRTIINTCDEFLFYNYRYWDNMTALWNPWLRQVRWIEYANQEFCVFGLGYDNSRPEKVYKILGHLFCHGKVLRDQKVVIYECASDSLRFIDRPEDDDWPITETAKRSNVSLNGNLYWFGCSNYENDEYYIRIFDFSTEDFKPFCLLPCQMSHSTDELVLAVYKGDRFSLLKQCSVTREIGVWVTKERISNDNGNGGEGVEWLKLMTLSKPNLPKLFGTVSYFIYGKTLYMCNGDDETALACIYIVREDVCKKFQIGSGNINCRHCVYTPNLLSLPLFIG
What is the function of this protein?
Regulates negatively a plant defense signaling pathway which is independent of salicylic acid (SA) and systemic acquired resistance (SAR).  Confers sensitivity to P. syringae and P. parasitica.
What are the official names of this protein?
Protein SUPPRESSOR OF NIM1 1.
Protein: KDKA_XANOR
Sequence: MVSFDATEALAPYREGRGYGAIVFDRERLRQADASLFSPQSWGDRARPVDKGGRGGAWFVDAPFGRSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLADHAQLAGRGAPWEATGQLIARFHRAGLDHPDLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSGEDVDKDYERLHRAYELAWGRGY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: XERD_HAEIN
Sequence: MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGERLEKGYKATSTARMLSAMRKLFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMSVQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADALSPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_BARBK
Sequence: MNSVNNIRSTFLDYFHRNGHEVLSSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEKHSYNRATTAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFSNYFKEEAIFYAWNLLTKEFCLSKDKLLVTVYHDDDVAAGLWRKISGLSEEKIIRIATNDNFWMMGDTGPCGPCSEIFYDHGDKIWGGPPGSADEDGDRFIEIWNLVFMQYEQLSKEKRIELPQPSIDTGMGLERIAAVLQGVHDNYDIDLFRTLIHASQEIIGVKATGDFFASHRVIADHLRSSAFLIADGIMPSNEGRGYVLRRIMRRAMRHAHLLGSKDLLMWRLVPVLISEMGQAYPELVRAESLISEILKLEETRFRKTLERGLGLLNEASTHLEEGDYFNGEVAFKLYDTYGFPLDLTQDALRRRGISVDVDAFDKAMKRQKAEARANWSGSGDCVTETVWFSIRDQVGATEFLGYETEKAEGIITALIRDGEVVDHIDLGQKAMIVVNQTPFYGESGGQVGDSGIISGANFIFEVHDTQKKGDNVFIHIGEIKTGQAKKHDCVELIVDSARRRKIRANHSATHLLHESLRQTLGSHVVQKGSFVSPDRLRFDFSHPKSISSEELKKIEDLANDIVLQNSKVTTRLMAIDDAIAEGAMALFGEKYGDEVRVISMGNNLEQTGSKKWWSIELCGGTHVQRTGDIGLIHIISETSVAAGVRRIEALTATAARLYLHGQDRRVYEIAGLLKTSPADVQERVQTLLDERRKLEKELNDSRKKIALNGGSVNSQGDIQTINGISFMGGVVSNILPKDLKALVDSGKKKIGSGVVAFISVSEDGKGSAVVGVTDDLTDTLNAVDLVRIISVTLGGQGGGGRRDMAQAGGSEGGKADEALVALKDSLKG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_PUFOP
Sequence: MAPNLRKSHPLLKMVNNSLIDLPAPSNISAWWNFGSLLGICLLTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYFTLKDILGFMLLLLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLAPFLHKAKQRAMTFRPISQLLFWILVANLFILTWVGSQPVEHPFIIIGQLASLTYFTILLILFPITGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PURL_METS5
Sequence: MILTLSKTEMEVVRRVLGREPKEAEWKLVDALWSEHCSYKSSKVFLRSLPSTGPNVIMSVEDWQDAGAVDVGDGLALVLKVESHNHPSAIDPFNGAATGVGGILRDIISKGAKPIALLDMIRVGKLDDKGKWLLKNIISGIGFYGNSVGVPVVGGELSFDETYNDNPLVDVACAGIVSKDSIVPSVVREPGLRLVLAGFTGLDGLGGASFASRKLSGMDEIGAVQIADPFAGKIIIDVTLEIAKEVEAIKDLGGGGLAVAVTEMANGLGAVVNLERVPLRFEYLSPEDIIISETQERMLFAVKPEKVESVCAKFREYNYPCEDIGEITAEPKVRFLYNGEPVAELPSDLLLSPPLNVWPAERKPRKREPEREVALGEALRAVLTHPDLVSKEWAYSQFDYEVGTSTVVKPGQGDSAVVELPNGKYLALKGDANQDLCAEDAYECGKAIVAEAYRNLATVGARGIALVDHLQFGDPRKPHVYQDFIDAVRGISEASKFFSIPVVGGKVSFHNEDKNGNPIKPTPLVVMAGLVEGKLARNRVEEGDLVLIGETRNELAGTLFSRIFGGGGEVAKTRLMEDLIASNLVIKGINEGKITWNKDVSKGGLAGALLPILAKGFSVRISSSQVIGTSNLLGKMFSESGGRFLVLTSDPQWFMYQAGRMGIQALAIGKVTKDGSKLVLDYETFPMDSIVENYYSFLEGSL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIVB2_BRUA2
Sequence: MKKSLFCGVCLCALVAMGGTSFADIMVGVGAPLTGSQAAFGEQIKRGVEAAVAEANAKGGMNGEQITLVYGDDAADPKQGISVANKFVGDGVKFVIGHFNSGVSIPTSDIYAENGVLMIAPGTTNPTFTERELWNTFRTCRRDDKQGIVPGKYMADNYKDGKVAILHDKTPYGQGLADETKKKLNELGTKETLYEGVNVGEKDFSALIAKLKQAGVNVVYWGGLHPEAGLIIRQMADQGLKAQFISGDGIVSNELASIAGPAVEGTLNTFGPDPRNNPDNAELVKKFRDAGFEPEAYTFYAYAGVQSLVNAANAAGSNDPMEVATAMKEKGPFKTVLGDISFDAKGDPSLSPYVMFEWRKGEDGKYNYFQK
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: NDHI_PEROV
Sequence: MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGHCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SYD_STRP2
Sequence: MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIVLNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEFIDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKDIEVTLPFPRMKYDDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDIDKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADTLEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQEETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTVALKQLEELSLQVEEDETSKTN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2891_MYCTO
Sequence: MAKSPARRCTAKVRRVLSRSVLILCWSLLGAAPAHADDSRLGWPLRPPPAVVRQFDAASPNWNPGHRGVDLAGRPGQPVYAAGSATVVFAGLLAGRPVVSLAHPGGLRTSYEPVVAQVRVGQPVSAPTVIGALAAGHPGCQAAACLHWGAMWGPASGANYVDPLGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKSPKQGVFRGAAQGGDIVARQPPGRWVCPSSAGGPIGWHRQ
What are the official names of this protein?
Uncharacterized protein MT2958.2.
Protein: ACP_BACAN
Sequence: MADVLERVTKIIVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_MARSD
Sequence: MLAILDYKAGNQTSVQRALNKLGIPNQITSDKEVLSKATGIIFPGVGAAGQAMDELTSGGLDELLKDLVQQKKPLLGICVGCQILLDYSEENDTQALSVIPGECRLFNPSWEDYEGVPIRVPHMGWNQIELKQDCILFKDIDPEAHFYFVHSYYPAPEEKYIIGETIYGRPFCSLHGREGLWAVQFHPEKSGRPGLKLLSNFYEYCKEVSDA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_PROMH
Sequence: MTLPINNNIFTVSRLNKTVRQLLEMEMGRIWISAEISNFTQPASGHWYFTLKDTHAQIRAAMFRGQNTKVTFRPQHGQQVLVRATITLYEPRGDYQLIVESMQPAGDGLLQQQFELLKQKLSAEGLFDALHKKPLPTPAKQIGVITSSTGAALHDILNILRRRDPSLPIIIYPTAVQGAEAPMQIVHAIELANRRKECDVLIVGRGGGSLEDLWAFNDERVARAIFASDIPIVSAVGHETDVTIADFIADLRAPTPSAAAELISRNKLELLRQLQSQQQRLEMAMDYYLAKKLRALTQLHHRLQQQHPHLRLARQQNVLATTKQRLVTSFQRLLQTKQNQHTQLQKRLNYQEPSPQIQALLRQQQQLIYRMRESISQQLARQREQFAISCSRLESVSPLATLSRGYSISEVASGDVLKNTKQVKKGDTLKTRVEDGWITSEVINTQKIPAKRKPAPKSKSSI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_SYNP2
Sequence: MPVVSLAELLESGVHFGHQTRRWNPRMAPYIYTSRNGVHIIDLVQTAQLVEQAYTYMKEASENGKHVLFVGTKRQAAGIIAQEAKRCGAFYINQRWLGGMLTNWETIKTRVERLKELEALEESGNLARRPKKEASMLRRELDKLQKYLGGIKNMRKIPDIVVIIDQRREHNAIQECQKLGIPIVSLLDTNCDPQTVDLPIPANDDAIRSIKLIVGKLADAIYAGRHGQPVDDNGDYGDFDEAIDEYADETDASESE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: UBA6_MOUSE
Sequence: MERSEPLAVLSCEEASCSSWGACGASKNLPTMTTESLEIDDGLYSRQRYVLGDTAMQKMAKSCVFLSGMGGLGVEIAKNLVLAGIKALTIHDTKKCQAWDLGTNFFLCEDDVVNERNRAEAVLHRIAELNPYVQVSSSSAPLDETTDLSFLEKYQCVVLTEIKLTLQKKINNFCHSHCPPIKFISADVHGIWSRLFCDFGDEFEVSDTTGEEPKEIFISNITQANPGIVTCLESHPHKLETGQFLTFREIHGMTGLNGSVQQITVISPFSFSIGDTTKLDPYLHGGIAVQVKTPKTFCFEPLESQIKHPRCLIADFSKPEAPLEIHLAMLALDQFQENYNRKPNIRCQQDSDELLKLTVSINETLEEKPEVNADIVHWLSWTAQGFLPPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADTVESLGNPGHEEFLPRGDRYDAIRACIGNTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKINPQLKIDAHLNKVCPATESIYSDEFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEIIVPQLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQAYPSAEDVLQKIQNGQSLEGCFQVIKLLSRRPRIWSQCVELARLKFEKYFNHKALQLLHCFPLETRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQSAAKLYATVYCIPFSEKDLSVNSLMDILSEVKIEEFKPSNKVVQTDETARKPDHVPVSSEDERNAVFQLEEALSSNKATKSDLQMTVLSFEKDDDRNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATSTAAVSGLVALEMIKVAGGYPFDAYKNCFLNLAIPIIVFTETSEVRKTEIRNGISFTIWDRWTVHGKEDFTLSDFINAVKENYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPSTEKKYVDLTVSFAPDADGDEDLPGPPVRYYFSHDTNE
What is the function of this protein?
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.  Specific for ubiquitin, does not activate ubiquitin-like peptides.  Differs from UBE1 in its specificity for substrate E2 charging.  Does not charge cell cycle E2s, such as CDC34 (By similarity).  Essential for embryonic development.  Required for UBD/FAT10 conjugation.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 6, Ubiquitin-activating enzyme 6, Ubiquitin-activating enzyme E1-like protein 2, E1-L2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: PLY3_ARATH
Sequence: MAAAFLNLGGYVFVFFSSFLAIVAPQVRGNVAVFDSYWTQRQSDALKQTIGSYDPHPLNVTNHFNYHVNIAVDASESRNDTRRELTQVRSGRKTHKSSGKCLAYNPIDNCWRCDRNWANNRKKLADCVLGFGRRTTGGKDGPIYVVKDASDNDLINPKPGTLRHAVTRDGPLWIIFARSMIIKLQQELMITSDKTIDGRGARVYIMEGAGLTLQFVNNVIIHNIYVKHIVPGNGGLIRDSEAHIGLRTKSDGDGISLFGATNIWIDHVSMTRCADGMIDAIDGSTAVTISNSHFTDHQEVMLFGARDEHVIDKKMQITVAFNHFGKRLEQRMPRCRYGTIHVVNNDYTHWEMYAIGGNMNPTIISQGNRFIAPPNEEAKQITKREYTPYGEWKSWNWQSEGDYFLNGAYFVQSGKANAWSSKPKTPLPNKFTIRPKPGTMVRKLTMDAGVLGCKLGEAC
What are the official names of this protein?
Probable pectate lyase 3, Pectate lyase A2.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: COF1_MACFA
Sequence: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPECAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
What is the function of this protein?
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (By similarity).  Important for normal progress through mitosis and normal cytokinesis (By similarity).  In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity).  Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity).  Required for neural tube morphogenesis and neural crest cell migration (By similarity).
What are the official names of this protein?
Cofilin-1, Cofilin, non-muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, growth cone. Cell projection, axon. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
Protein: HRCA_BACC0
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITYSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPNDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANMLSQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: TSP_BPBMU
Sequence: MAANYLHGVETIEKETGSRPVKVVKSAVIGLIGTAPIGPVNTPVQSLSDVDAAQFGPQLAGFTIPQALDAVYDYGSGTVIVINVLDPAVHKSNAANEPVTFDAATGRAKLAHPAAANLVLKNDSGGTTYAEGTDYAVDLINGVITRIKTGTIPPGATAAKATYDYADPTKVTAADIIGAVNAAGMRTGMKALKDTYNLYGYFSKILIAPAYCTQNSVSVELEAMAVQLGAIAYIDAPIGTTLAQALAGRGPAGTINFNTSSDRVRLCYPHVKVYDTATNAERLEPLSSRAAGLRARVDLDKGYWWSSSNQQLVGVTGVERPLSAMIDDPQSDVNMLNEQGITTVFSSYGSGLRLWGNRTAAWPTVTHMRNFENVRRTGDVINESLRYFSQQFVDAPIDQGLIDSLVESVNGFGRKLIGDGALLGFKAWFDPARNPKEELAAGHLLINYKYTVPPPLERLTYETEITSEYLLTLKGGN
What is the function of this protein?
Polymerizes as an extended structure around the baseplate-tail tube complex.  During ejection, the sheath shifts to a contracted form, thereby making the inner tail tube protrude through the host cell envelope.
What are the official names of this protein?
Tail sheath protein, TSP.
What is the protein family that this protein belongs to?
Belongs to the myoviridae tail sheath protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Tail.