PharMolix/UniProtQA huggingface dataset:
Protein: HELY_MYCTU
Sequence: MTELAELDRFTAELPFSLDDFQQRACSALERGHGVLVCAPTGAGKTVVGEFAVHLALAAGSKCFYTTPLKALSNQKHTDLTARYGRDQIGLLTGDLSVNGNAPVVVMTTEVLRNMLYADSPALQGLSYVVMDEVHFLADRMRGPVWEEVILQLPDDVRVVSLSATVSNAEEFGGWIQTVRGDTTVVVDEHRPVPLWQHVLVGKRMFDLFDYRIGEAEGQPQVNRELLRHIAHRREADRMADWQPRRRGSGRPGFYRPPGRPEVIAKLDAEGLLPAITFVFSRAGCDAAVTQCLRSPLRLTSEEERARIAEVIDHRCGDLADSDLAVLGYYEWREGLLRGLAAHHAGMLPAFRHTVEELFTAGLVKAVFATETLALGINMPARTVVLERLVKFNGEQHMPLTPGEYTQLTGRAGRRGIDVEGHAVVIWHPEIEPSEVAGLASTRTFPLRSSFAPSYNMTINLVHRMGPQQAHRLLEQSFAQYQADRSVVGLVRGIERGNRILGEIAAELGGSDAPILEYARLRARVSELERAQARASRLQRRQAATDALAALRRGDIITITHGRRGGLAVVLESARDRDDPRPLVLTEHRWAGRISSADYSGTTPVGSMTLPKRVEHRQPRVRRDLASALRSAAAGLVIPAARRVSEAGGFHDPELESSREQLRRHPVHTSPGLEDQIRQAERYLRIERDNAQLERKVAAATNSLARTFDRFVGLLTEREFIDGPATDPVVTDDGRLLARIYSESDLLVAECLRTGAWEGLKPAELAGVVSAVVYETRGGDGQGAPFGADVPTPRLRQALTQTSRLSTTLRADEQAHRITPSREPDDGFVRVIYRWSRTGDLAAALAAADVNGSGSPLLAGDFVRWCRQVLDLLDQVRNAAPNPELRATAKRAIGDIRRGVVAVDAG
What are the official names of this protein?
Probable helicase HelY.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
Protein: RS8_SYNC1
Sequence: MAMTDPIADMLTRIRNAGLAKHQKCDMPASNVKLAIVNVLKELGYIKNFKQISDDKQGILRIYLKFDNENKHIIHAIDRVSTPGCRVYVGKDEIPVVKNGLGNAILSTSKGVMHDAAAREAQLGGEVLCSVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PANB_BORPE
Sequence: MSVPTAAKRITTRQLRMRTPDEPIVALTAYTAPIAGLLDAHCDLLLVGDSLGMVIYGMETTLPVTVDMMIQHGRAVMRGSQRACVAVDMPFGSYQEDERQAYRNAARIMAETGASCVKLEGGAEMASTVAFLVERGIPVMGHVGLKPQSVHGHGGFRTVGRGAEAEQVMADAQAIAAAGAFTVVIEGTLEPVARAITEALPVPTIGIGASPACGGQILVSDDVLGLFSDFTPRFVKRYAQLGPIIEQAAAAYASEVRARTFPAPEHCTGMPAPDGRPA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMEDA_ASHGO
Sequence: MKYTTFGIISLFLSVTWALRFELAASFEPKPFCIRDFVEAGNQVVITMESDGRVGDGQVLSFYVIDSMGNEHRRKKNFAEKLNVAFTAPSSAVFDVCFENKAEAAGRSLMRNVEVNIESGSAARDWDKIRSAEKLRPAEVQLRQVEEMSDEIVERLNYLKLREERLRDTNESTNRRVRNFSMAVIVVFAALCAWQLNYLKNYFRAKHII
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: KCY_METM5
Sequence: MIITIGGLPGTGTTTTSKLLSEKYGLKHVCAGFIFRDMAKEMNMTLQEFSSYAETNTEVDNEIDRRQVEAAQSGDLILEGRLAGWILKKSDIKPDLSIWLKADPMVRCVRISERENENVDLALEKMISREASEKKRYKEIYNIEIDDLSIYDLVIESSKWDANGVFNIIEKAIDNLKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_PYRFU
Sequence: MPKQVVEVLVEGGKATPGPPLGPAIGPLGLNVKQVVDKINEATKDFAGMQVPVKIIVDPVTKQFEIEVGVPPTSQLIKKELGLEKGSGEPKHNIVGNLTMEQVIKIAKMKKDQMLALTLKAAAKEVIGTALSMGVTVEGKDPREVQKEIDEGVYDELFEKAEKE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11, Large ribosomal subunit protein uL11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HEM3_SHEON
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKSISELPLGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEGGCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAKSILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MSHD_MYCBP
Sequence: MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRTEHLLVAGSRPGGPIIGYLNLSPPRGAGGAMAELVVHPQSRRRGIGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPLRDIPEPTIPDGVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQLAERRGEAWFDPDGLILAFGDSPRERPGRLLGFHWTKVHPDHPGLGEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLYVESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: QUEC_PECCP
Sequence: MKRAVVVFSGGQDSTTCLIQALQHYDDVHCITFDYGQRHRAEIDIARELSLKLGATAHKVLDVGLLNELATSSLTRDSIPVPDYDANAQGIPNTFVPGRNILFLTLASIYAYQVGAEAVITGVCETDFSGYPDCRDEFVKALNQAIVLGIARDIRFETPLMWLNKAETWALADYYQQLDTVRYHTLTCYNGIKGDGCGQCAACHLRANGLAQYQNDSAAVMASLKQKAGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: EFG1_DESPS
Sequence: MSKDLSKVRNIGISAHIDSGKTTLTERILFYTDRIHAIHEVRGKDGVGAKMDSMELEKERGITIQSAATFCNWKGTDINIIDTPGHVDFTVEVERALRVLDGAVLVLCSVGGVQSQSITVNRQMTRYNVPRIAFINKCDRTGANPAKVTGQLQEKLQLNAHMMQMPIGLEGDLVGMVDLVTMKAVYYEGENGDEIRITDIPAEMLDEATEKRETLLEEISMFSEELMEALLEDSENVDIDLIYKAVRQGTIALEFTPVFMGSAYKNKGVQALLDAVETYLPCPTDVENIGLDLDNEETEFAVTNNDEDPLIMLAFKLEDGRYGQLTYVRTYQGQLTKGDTVYNRRTGRKVKIGRLCRMHSDEMEEIDGVGSGDIVALFGVDCASGDTFTNDAVNCSMTSMHVPEPVISLSIKPIDNKAQINMSKALNRFTKEDPTFRTFVDHETNETIISGMGELHLEVYVERMKREYAAEVEVGKPQVSYRETITQRAEFNYTHKKQTGGTGQFGRVAGYMEPLDEGDYEFVDKIVGGAIPREFISSCDKGFQKSLVKGHLCGAGITGVRCVINDGSFHAVDSSDVAFQIASVGAFKDGYMKAKPVIMEPIMKVSVEGPSEFQGAVMGSINQRRGMIIGSNEEGTYSVIEAEVPLSEMFGYSTTLRSLTQGKAEFTMEFANFKPVPKTVGDNLIKAHEEERKNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_RHOPB
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTSLTAAITKVLAETGGATFTAYDQIDKAPEEKARGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFLNKCDMVDDPELLELVEMEVRELLSKYDFPGDDIPIVKGSALAALENKDPKLGHDAILELMKAVDAYIPQPERPIDQPFLMPVEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGLRDTQKTIVTGVEMFRKLLDQGQAGDNIGALLRGTKREEVERGQVLCKPGSVKPHTKFKAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNIAMEVHLIVPIAMEEKLRFAIREGGRTVGAGVVASIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_STAA1
Sequence: MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL19_SHEON
Sequence: MNNIIKMLNDEQMKQDVPAFGAGDTVVVQVRVKEGDKERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPLIASIEVKRRGRVRRAKLYYLRDRSGKSARIREKLATK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: WHIA_FRAAA
Sequence: MTATVKDELSRLRVAKPCCRRAEMAALLRFGGGLHIVGGRIVVEAELDTGATARRLRREVAEVFGFPSTVAVLAAGGLRRSVRYIVRVERDGEQLARSTGLLDQRGRPVRGLPPQVVTGSACDAAAAWRGAFLAHGSLTEPGRSCSLEVTSPGPEAALALVGAARRLGVQAKSRDVRGVDRVVIRDGDAIGALLTKIGAHDSLMAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARVQAAMRILGDDAPEHLLAAGRLRLEHAQASLEELGALADPPLTKDAVAGRIRRLLALADKRANALGIPNTEASVSPDLLENA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: GPXC_DIRIM
Sequence: MFIQLLILSYAILLQLIATQVADKQLPNLTKQCEPTSQTIYDFHVPTLDGSEKSLAEYRGKVLLLVNVATYCAYTFQYNDFNPMLENNSNGTLKILAFPCNQFLLQEPAENHELLNGLKYVRPGNGWEPHGNMHIFGKVEVNGDDHHPLYKFLKEHCPQTVPIIGDRHQLMYNPIGTNDIIWNFEKFLIDKKGHPRYRFHPSAWVQGSVIAPFIDELEREI
What are the official names of this protein?
Glutathione peroxidase, Di29.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MATK_NICGL
Sequence: MEEIQRYLQPDRSQQHNFLYPLIFQEYIYALAHDHGLNRNRLILLENPGYNNKFSFLIVKRLITRMYQQNHFLISTNDSNKNAFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKIFKSHNLRSIHSTFPFLEDNFSHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEYWNLNSLITSKKPGYSFSKKNQRFFFFLYNSYVYECESTFVFLRNQSSHLRSTSFGALLERIYFYGKIERLVEVFAKDFQITLWLFKDPFMHYVRYQGKSILASKGTFLLMNKWKFYLVNFWQCHFSLCFHTGRIHINQLSNHSRNFMGYLSSVRLNPSMVRSQMLENSFLINNAIKKFDTLVPLIPLIGSLAKANFCTVLGHPISKPVWSDLSDSDIIDRFGRICRNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRTFFKRSGSELLEEFLTSEEQVLSLTFPRASSSLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HDAC8_XENTR
Sequence: MEESLLPVYIHSAEYVELCDNVQSKVPRRASMVHSLIEAYGLLKEMRVVKPKVASMEEMAAFHTDSYLQHLHKVSEEGDNDDPETLEYGLGYDCPITEGIYDYAAAVGGATLTAAEQLMAGKTRIAINWPGGWHHAKKDEASGFCYLNDAVLGILKLREKFDRVLYVDMDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDIGLGKGRYYSVNVPLQDGIQDEKYYQICEGVLKEVFTTFNPEAVVLQLGADTIAGDPMCSFNMTPQGIGKCLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPDYVLEVTPSCRPDRNDSQKVQEILQSIKGHLKQVV
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Also involved in the deacetylation of non-histone proteins.  In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
What are the official names of this protein?
Histone deacetylase 8, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Excluded from the nucleoli. Found in the cytoplasm of cells showing smooth muscle differentiation.
Protein: RS3_YEAST
Sequence: MVALISKKRKLVADGVFYAELNEFFTRELAEEGYSGVEVRVTPTKTEVIIRATRTQDVLGENGRRINELTLLVQKRFKYAPGTIVLYAERVQDRGLSAVAQAESMKFKLLNGLAIRRAAYGVVRYVMESGAKGCEVVVSGKLRAARAKAMKFADGFLIHSGQPVNDFIDTATRHVLMRQGVLGIKVKIMRDPAKSRTGPKALPDAVTIIEPKEEEPILAPSVKDYRPAEETEAQAEPVEA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S3, RP13, Small ribosomal subunit protein uS3, YS3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_CERSK
Sequence: MAGEIPDFQAEVRTGTGKGAARQARREGYVPGIVYGGGQEPLSINVPYNDLLNRLKKGRFLQTLFNLKVEGQEDVRVICRGVQRDVVKDLPTHVDFMRLRRTSRVNLFIHVTFENHDKAPGLKRGGTLTVVRPEVELEVTAGDIPDHLTVDLTDRQIGDVIHINDIKLPEGAVPTINRNFVIANISAPSGLRSSDNEEEAEEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: AMY1_DICT6
Sequence: MTKSIYFSLGIHNHQPVGNFDFVIERAYEMSYKPLINFFFKHPDFPINVHFSGFLLLWLEKNHPEYFEKLKIMAERGQIEFVSGGFYEPILPIIPDKDKVQQIKKLNKYIYDKFGQTPKGMWLAERVWEPHLVKYIAEAGIEYVVVDDAHFFSVGLKEEDLFGYYLMEEQGYKLAVFPISMKLRYLIPFADPEETITYLDKFASEDKSKIALLFDDGEKFGLWPDTYRTVYEEGWLETFVSKIKENFLLVTPVNLYTYMQRVKPKGRIYLPTASYREMMEWVLFPEAQKELEELVEKLKTENLWDKFSPYVKGGFWRNFLAKYDESNHMQKKMLYVWKKVQDSPNEEVKEKAMEEVFQGQANDAYWHGIFGGLYLPHLRTAIYEHLIKAENYLENSEIRFNIFDFDCDGNDEIIVESPFFNLYLSPNHGGSVLEWDFKTKAFNLTNVLTRRKEAYHSKLSYVTSEAQGKSIHERWTAKEEGLENILFYDNHRRVSFTEKIFESEPVLEDLWKDSSRLEVDSFYENYDYEINKDENKIRVLFSGVFRGFELCKSYILYKDKSFVDVVYEIKNVSETPISLNFGWEINLNFLAPNHPDYYFLIGDQKYPLSSFGIEKVNNWKIFSGIGIELECVLDVEASLYRYPIETVSLSEEGFERVYQGSALIHFYKVDLPVGSTWRTTIRFWVK
What is the function of this protein?
This amylase is a highly liquefying-type: oligomers appeared at the beginning of incubation, followed by a graded decrease in the amounts of maltotriose, maltose and glucose in prolonged incubation.
What are the official names of this protein?
Alpha-amylase 1, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 57 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y827_RICTY
Sequence: MNKFYIYNNFKNEALINIKVKPYSKQNLINNFVIINNIPYIKLSITAAPEQGKANEGIINYLAKEWKLSRSSIEIIKGHTHSLKTILIKNINEDYLNLIINSYIK
What are the official names of this protein?
UPF0235 protein RT0827.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: TIG_XANC5
Sequence: MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTKLSVVRATAEVTDADIDQMIENLRLQRRTWNPVERGAQVGDLVALETWSQAGDERLPAEGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLTVDFPAEWRVPQLAGKTVQVHVKAVEVSEPVLPAVDKEFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVENEARSMLAQQVEQVRRSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESKRVSETLRLIASTYEEPEQVIEMYRNDPQLMNGLQSRVMEEQVIDWIAERAQHTEQSLSFQDAIRV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS8_FRACC
Sequence: MTMTDPIADMLTRVRNASRAYHDRVVMPHSKIKTHIAEILQQEGYISGWHVEDATSAGGVGHTLVIDLKYGPNRERSIAGIKRISKPGLRVYAKATNLPKVLGGLGVAIISTSSGLLTDKQAGKRGVGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS15_MYCSS
Sequence: MALTAEQKKEILGQYGLHESDTGSPEAQVALLTKRISDLTEHLKQHKHDHHSRRGLLLLVGRRRRLLKYVAQVDVERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PFKB_ECOLI
Sequence: MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 2, ATP-PFK 2, Phosphofructokinase 2, 6-phosphofructokinase isozyme II, Phosphohexokinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: SL2_BITGA
Sequence: MGRFIFLSSGLLVVFLSLSGADFECPSEWRPFDQHCYRAFDEPKRSADAEKFCSEQGNSGHLVSIQSKEEADFVAQLISDNIKSSPDYVWMGLWNQRREQYCSRKWTDGSNVIYKNVAERFTKNCFGLEKETEYRTWLNILCGDDYPFVCKFPPRC
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 2, C-type lectin 2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGA_JANMA
Sequence: MLTFQQIILTLQKYWDAQGCALLQPYDMEVGAGTSHTATFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQVVLKPAPANILELYLGSLEALGFDLKANDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGINCKPITGEITYGLERLAMYLQGVDNVYDLRWTDKLSYGDVYKQNEIEQSTYNFEHSDADFLFTAFGAHEKQALNLIDNKLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLARSVARSYLDSRARLGFPMAKPEHAAEVLAQIEKEAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DX39B_PIG
Sequence: MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
What is the function of this protein?
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint.  Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity.  Even with the stimulation of RNA, the ATPase activity is weak.  Can only hydrolyze ATP but not other NTPs.  The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA.  However, ssRNA stimulates the ATPase activity much more strongly than dsRNA.  Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro.  The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly with [] reporting a stimulatory effect.
What are the official names of this protein?
Spliceosome RNA helicase DDX39B, 56 kDa U2AF65-associated protein, DEAD box protein UAP56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: PLSX_PARL1
Sequence: MTRGLTIALDGMGGDHGPETVIGGADIASVRHPDIRFLIYGDETKIRPFLEKHPRVLSVSEIIHTDVSVSMEDKPSQALRRGRKTSSMWLAIDAVKAGEAQAAVSAGNTGALMAMAKVILRMMPNVERPALAALWPTARGESVMLDLGATVGADGYQLVQFAAMGEAFARVVFNIEQPTVGLLNIGEEEVKGTEGVKLAAQMLREADLPIRFHGFVEGDDIAKGTVDVVVTDGYTGNIALKTAEGMVRLVVDYLRAAMRSSLLSRLGYLLAYGAFRALAKKLDPRASNGAVFLGLNGLVVKSHGGTDAIGFAAAIDVAVDVASADLLSKIVTDLDRLSGLTTSMAGRKQNSDIAESEAVLS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.