PharMolix/UniProtQA huggingface dataset:
Protein: IF4A_YEAS7
Sequence: MSEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Stimulator factor I 37 kDa component, Translation initiation factor 1/2, p37.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_ECOSE
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_BURM1
Sequence: MSFSRSAADPADTLPDLAATLAAPDTHAFLRLGDAFHTRLPAAPLAAPYVVGFSDEVARLLGLPASLAAQPGFAELFAGNPTRDWPAEALPYASVYSGHQFGVWAGQLGDGRALTIGELPGTDGRRYELQLKGSGRTPYSRMGDGRAVLRSSIREFLCSEAMHHLGIPTTRALTVIGSDQPVVREEIETAAVVTRVSESFVRFGHFEHFFSNNRPDLLRALADHVIDRFYPACRDADDPYLALLEAATRRTAELVAQWQAVGFCHGVMNTDNMSILGVTIDYGPFGFVDAFDANHICNHSDTGGRYAYRMQPRIAHWNCYCLAQALLPLIGLQHGIADDDARAERAVDDAQAVLATFPERFGPALERAMRAKLGLALERDGDAALANQLLETMHASRADFTLTFRRLAQLSKHDASRDAPVRDLFIDREAFDAWANLYRARLSEETRDDAARAAAMNRVNPKYVLRNHLAELAIRRAKEKDFSEVERLAQVLRRPFDEQPEHESYAALPPDWAGSLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PFLA_ECOL6
Sequence: MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWDTHGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHTCLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYKLDGVKPPKKETMERVKGILEQYGHKVMF
What is the function of this protein?
Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Pyruvate formate-lyase 1-activating enzyme, Formate-C-acetyltransferase-activating enzyme 1, PFL-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRM1_YEAS7
Sequence: MSIMKQRLPLGEFSSSKINKLAIANIADASEPRNHGENNVGTVCLPSIKSLMVSPEVYENTKSLPVPLMRSSGGGMACASKSSCQDGISTKTTSRDYSELSKKLQIRLQFAYYKYKTKQTDKNFTDLKSKHSITRPSKVATHSKSEPLTRRRKLVLSQGHYKTPARSKIKTPSSICSHDNTSSFTSFRGVSESSSTTADMNVADTTTPIRNNINTKHSNSHNRTLYQRQETPTSIKAAKSLIHLFTSNQ
What is the function of this protein?
Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription.
What are the official names of this protein?
Transcription factor NRM1, Negative regulator of MBF targets 1.
What is the protein family that this protein belongs to?
Belongs to the WHI5/NRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: WCWK1_STREE
Sequence: MKNMEQIDFVVTWVNNKDVDWCKRKSEFEKEYNIFQDLNSEERYREWGFMKYWFRAVEKYAPWVNKIYFITEGHVPNWLDVNHPKLVHVKHEDYIEKQFLPTFNSNVIEMNLIHLKDLSEKFVLFNDDTFINDFVKQSDFFENNLPKDTGIFSPLIPRENSLTPIVLNNMEIINKYFSKKKILEQNFSKFFNIKYGKHLLKNICLLPWSDLLGFYNSHIPVSYCKSNFLEVYEKEYDIFNLTFKNKFRNKNEINHWLIRYWQLSSGNFIPRNINFGKNYAISNDPTDIINELKFSKYKIICINDGESIDSFDEVKDLMIDAFEKKFPEKSSFEKK
What are the official names of this protein?
Capsular polysaccharide phosphotransferase WcwK, Stealth protein WcwK.
What is the protein family that this protein belongs to?
Belongs to the stealth family.
Protein: PURL_STAAM
Sequence: MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASF1_KLULA
Sequence: MSIVSLLGIKVLNNPAKFTDPYEFEITFECLEPLKHDLEWKLTYVGSSRSLDHDQELDSILVGPIPVGINKFKFVADAPSPDLIPASELVSVTVILLSCSYNGKEFVRVGYYVNNEYDLEELRENPPQKVPIDHVVRNILAEKPRVTRFNIVWDNEGEEEFYPPEQEEPEEEEEEEEDEDEDEEADEDAEEDLAEEDDVDDGEGEETAPEKKKLKRDPKKSTASDVKNDEGESQAESLGPEEDEEDEEEAEEIDLEKESDSENDADLPTPQDTTQHK
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: C2CD5_PONAB
Sequence: MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTAIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAAFLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSAGSVKLLDRIHNPDEPETRDAWWAEIRQEIKSLAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPTRCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPTDATVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFIEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEKEINQGTSTASPKNFDKKQALQTTKTPVEKSLQRASTDNEELLQFPLELCSDSFPSHPFPPAKAVTVERASPVGDGNFRNRSAPPCANSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESDLEVVSSQQPTTNCQSSCTESEVTT
What is the function of this protein?
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes.  Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
What are the official names of this protein?
C2 domain-containing protein 5, 138 kDa C2 domain-containing phosphoprotein.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.
Protein: MATK_PINPU
Sequence: MDEFHRYGKEDNSRQQCFLYPLFFQEDLYAISHDHYLDGSSSSEPMEHLSSNDQFSFLTVKRLIGQIRQQNHSIVLFVNCAPNPLADCKKSSYSESVLEGLTLVLEVPFSIRSKYSVEGMNEWKSFRSIHSIFPFLEDKFPHSNYISDARIPYSIHPEILVRTFRRLIRDAPSLHPLRSVLYEYRNSPENLQRSIIVVPRVNTRFFLFLWNYYVYECESILFSLLKRSSHSRSVAHRPFPQRTHFHRKIKHIIIFSRRNSLKSIWLLKDPKINYVRYGERSIIAIKGTHLLVKKCRYYLLLFRQCYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPLFVRTKMLDELFIADLITNEFDPIVPIVPILGLLAREKFCDVSGRPISKLSWTNLTDDDILNRFDQIWRNLFHYYSGSFGRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFQKSFSKEREFDSLPFSSKAAARSQRERIWHSDIPQINPLVNSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMA_BURMS
Sequence: MTKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAQTIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTRVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKTVGEHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAVKDIASNTLYVVQGHDHPWLRSRELVAGNVSWVAGEPPADGARCGAKTRYRQADAPCAFGRAAQAGDERFSLVFDEPQWAVTPGQSAVLYDGDVCLGGGIIESAATGRAGTAPAGRAPALVEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_CHLCV
Sequence: MAWENVRVRVAPSPTGDPHVGTAYMALFNEIFAKRFNGKMILRIEDTDQTRSRDDYEKNIFSALQWCGIQWDEGPDIGGPHGPYRQSERTEIYREYAELLLKTDYAYKCFATPKELEEMRAVATTLGYRGGYDRRYRYLSPEEIEARTQEGQPYTIRLKVPLTGECVLEDYCKGRVVFPWADVDDQVLMKSDGFPTYHFANVVDDHLMGITHVLRGEEWLSSTPKHLLLYEAFGWEPPIFLHMPLLLNPDGTKLSKRKNPTSIFYYRDAGYIKEAFMNFLTLMGYSMEGDEEVYSLEKLIANFDPKRIGKSGAVFDVRKLDWMNKHYLNHEGSPENLLARLKDWLVNDEFLLKILPLCQSRMATLAEFVGLSEFFFSVLPEYSKEELLPAAISQEKAAILFYSYVKYLEKTDLWVKDQFYLGSKWLSEAFQVHHKKVVIPLLYVAITGKKQGLPLFDSMELLGKPRTRMRMVHAQNLLGGVPKKIQTAIDKVLKEENFENKILEF
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2314_STAEQ
Sequence: MTKFNFDQVHSDIQFKIKHLMVSQVKGTFKQFDVQLDGDINDLTSLKATATIIPSSIDTQNEDRDNHLRSNDFFGTEDNDKMTFVTKEINENQVVGDLTIKGETHEETFDVEFNGVSKNPMNGQQVTGFIVSGTINREKYGINFNQALETGGVMLGKNVKFEASAEFSIDN
What are the official names of this protein?
UPF0312 protein SERP2314.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family.
Protein: FGF1_MOUSE
Sequence: MAEGEITTFAALTERFNLPLGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTEGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrin ITGAV:ITGB3.  Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling.  Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1.  Can induce angiogenesis.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1. Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59 (By similarity).
Protein: AGRB_STAHJ
Sequence: MKAIDNKIEQFALYLQRKNNLDHIQFLKVRLGLQVVVSNLAKTIVTYGVALIFHTFLYTLFTHVSYFLVRRYAHGAHAKSSLLCHVQNLALFVALPWLLVYFQVNLGIMYSVVAIGTVLIIYYAPSATKKQPIPSHLKMKKKLLSIIITMVLLIISFLAPEPFKQLILLGITLESITLLPIFFPREDN
What is the function of this protein?
Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP).  This quorum sensing system is responsible for the regulation of the expression of virulence factor genes.  Involved in the proteolytic processing of AgrD, the precursor of AIP.
What are the official names of this protein?
Accessory gene regulator protein B.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DRP3A_ARATH
Sequence: MTIEEVSGETPPSTPPSSSTPSPSSSTTNAAPLGSSVIPIVNKLQDIFAQLGSQSTIALPQVVVVGSQSSGKSSVLEALVGRDFLPRGNDICTRRPLVLQLLQTKSRANGGSDDEWGEFRHLPETRFYDFSEIRREIEAETNRLVGENKGVADTQIRLKISSPNVLNITLVDLPGITKVPVGDQPSDIEARIRTMILSYIKQDTCLILAVTPANTDLANSDALQIASIVDPDGHRTIGVITKLDIMDKGTDARKLLLGNVVPLRLGYVGVVNRCQEDILLNRTVKEALLAEEKFFRSHPVYHGLADRLGVPQLAKKLNQILVQHIKVLLPDLKSRISNALVATAKEHQSYGELTESRAGQGALLLNFLSKYCEAYSSLLEGKSEEMSTSELSGGARIHYIFQSIFVKSLEEVDPCEDLTDDDIRTAIQNATGPRSALFVPDVPFEVLVRRQISRLLDPSLQCARFIFEELIKISHRCMMNELQRFPVLRKRMDEVIGDFLREGLEPSEAMIGDIIDMEMDYINTSHPNFIGGTKAVEAAMHQVKSSRIPHPVARPKDTVEPDRTSSSTSQVKSRSFLGRQANGIVTDQGVVSADAEKAQPAANASDTRWGIPSIFRGGDTRAVTKDSLLNKPFSEAVEDMSHNLSMIYLKEPPAVLRPTETHSEQEAVEIQITKLLLRSYYDIVRKNIEDSVPKAIMHFLVNHTKRELHNVFIKKLYRENLFEEMLQEPDEIAVKRKRTQETLHVLQQAYRTLDELPLEADSVSAGMSKHQELLTSSKYSTSSSYSASPSTTRRSRRAGDQHQNGYGF
What is the function of this protein?
Involved in the control of mitochondrial and peroxisomal division and morphology.  In association with PEX11C, PEX11D, PEX11E and FIS1B, is involved in cell cycle-associated constitutive self-replication of preexisting peroxisomes.
What are the official names of this protein?
Dynamin-related protein 3A, Dynamin-like protein 2, Dynamin-like protein 2a.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Mitochondrion. Peroxisome.
Protein: LIPA_ACIAC
Sequence: MSTPEVVREAQSTVAYNPLAKQKAAAKLSRIPIKVEQGEVLKKPEWIRVKAGSPTTRFYEIKEILREHKLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDKDEPLNLARTIAALKLKYVVITSVDRDDLRDGGSGHFVECIQNIRALSPATQIEILVPDFRGRDDRALEILKAAPPDVMNHNLETAPRLYKEARPGSDYQFSLNLLKKFKALHPGVPTKSGIMVGLGETDEEILQVMRDMRAHDIDMLTIGQYLAPSNSHLPVRRYVHPDTFKMYEEEAYKMGFTHAAVGAMVRSSYHADQQAHAAGLQAGPQG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_HIS1I
Sequence: MVEIDDGVEMAVGIFVVIILAANLLPTAFDQIFNASTSSWNSDVTTLWELLPLLSVVGLLLMFVYWARKAGKM
What are the official names of this protein?
Major capsid protein, MCP, Major coat protein, VP21.
What are the subcellular locations of this protein?
Virion. Note=Capsid protein.
Protein: RL34_SULNB
Sequence: MKRTYQPHNTPRKRTHGFRTRMKTKNGRKVISARRAKGRKRLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RAS1_YEAST
Sequence: MQGNKSTIREYKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAKQAINVDEAFYSLIRLVRDDGGKYNSMNRQLDNTNEIRDSELTSSATADREKKNNGSYVLDNSLTNAGTGSSSKSAVNHNGETTKRTDEKNYVNQNNNNEGNTKYSSNGNGNRSDISRGNQNNALNSRSKQSAEPQKNSSANARKESSGGCCIIC
What is the function of this protein?
The S. cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: YO011_HUMAN
Sequence: MYVSISFLLGLSHLVLCCLLTFIVNFYLPPESIDFEFMAHNWSKGRSPSSTLGLSWFKAGFRFSDGWSMFYSSGLPGVALPGSPPRSHLLPGTQILIRSFQPCESAKHSARLSSLLTTTSYSVS
What are the official names of this protein?
Putative transmembrane protein ENSP00000320207.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MODC_RHIEC
Sequence: MTLIVEAKQRLGAFSLDAAFTSEGGVTAFFGRSGSGKTSLIRIIAGLARPDGGRVVLDGERLTETTAGIFVPKHRRRFGYVFQEARLFPHLSVRANLSYGRWFAPKAGRSESFDHIIDLLGIETLLERSPAKLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDEARKAEILPYLERLRDETEIPIVYVSHSIAEVARLANQVVVLSDGKVQATGPAVDILSRPSAAADRKEAGALLEGTVESFDARHRLSTVTLKSSQLHIPSAVLTPGRPVRIRIPSRDVMLATARPEGLSALNILEGRIEAISPGEDGTVEIRIDCAGDAILSRITALSCERLDLRPGKTVFAIIKTVALEG
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LRC33_MOUSE
Sequence: MEFPPLWLCLGFHFLIVEWRSGPGTATAASQGGCKVVDGVADCRGLNLASVPSSLPPHSRMLILDANPLKDLWNHSLQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLSENYKESAAALHTLLGLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLLFFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISLCPQMVPVDWEGPPSCVDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGVLNGSISPLWAVAPTLQVLSLRDVGLGSGAAEMDFSAFGNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPQRVVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQQHFKTVADLSMVTCNLSSKIVRVVELPEGLPQGCKWEQVDTGLFYLVLILPSCLTLLVACTVVFLTFKKPLLQVIKSRCHWSSIY
What is the function of this protein?
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system (PubMed:29909984).  Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1 (PubMed:29909984).  TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighboring microglia, suggesting the existence of localized and selective activation of TGF-beta-1 by LRRC33/NRROS (PubMed:29909984).  Indirectly plays a role in Toll-like receptor (TLR) signaling: ability to inhibit TLR-mediated NF-kappa-B activation and cytokine production is probably a consequence of its role in TGF-beta-1 signaling (Probable).
What are the official names of this protein?
Transforming growth factor beta activator LRRC33, Leucine-rich repeat-containing protein 33, Negative regulator of reactive oxygen species.
What is the protein family that this protein belongs to?
Belongs to the LRRC32/LRRC33 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RPOA_NANDO
Sequence: MLREEVAVSTRTLQWRCVESRTDSKRLYYGRFVLSPLMKGQADTIGIAMRRALLGEIEGTCITHAKSEKIPHEYSTIVGIEESVHEILMNLKEIVLRSNLYGTCDASICVKGPINITAKDIISPPSVEIVDTTQHIASLTEPFDLCIGLQIERNRGYRMKTPNKAQNGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEQDIILEDNQNRVTLPFFTFHDGLAKLKKKNEIALKFIFIDQSELPSRTYNCLKKSNINTLLDLLNKSQEDLLKIEHFRIEDVKRVLGILQKRFVIDLPKNKFSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FRIL_SHEEP
Sequence: MEAALLVEKNLNQALLDLHGLASARGDPHICDFLENHFLDEEV
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin light chain, Ferritin L subunit.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: MSHD_MYCA9
Sequence: MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFLNLVVPDEAASENATAMAELVVAPAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQDDSDLLRVNNAAFSWHPEQGGWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQGRGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.