PharMolix/UniProtQA huggingface dataset:
Protein: BIOD2_ECOLI
Sequence: MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 2, DTB synthetase 2, DTBS 2, Dethiobiotin synthase 2.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CLOBO
Sequence: MRIKPLGDRVVIKRLEAEEKTKSGIVLPGSAKEKPQEAEIVAVGPGGLVDGKEVNMEVKVGDRVLFSQYAGNEVKIDGEEYIILRQNDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_THEYD
Sequence: MDFHGTTVLCVKRNDSVIIASDGQVTMGNTVLKHNAKKIRKLYNGQVLTGFAGSTADAFTLFERFEGKLETYKGNLLRAAVELAKDWRTDKILRRLEALLIVADKEHILIISGNGDVIEPEDQVAAIGSGGPFAFAAAKALYDNTELPAKEIAIKAMEIASKICIYTNNIIITEELS
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECD_MYCTO
Sequence: MKLTDVDFAVEASGMVRAFNQAGVLDVSDVHVAQRLCALAGESDERVALAVAVAVRALRAGSVCVDLLSIARVAGHDDLPWPDPADWLAAVRASPLLADPPVLHLYDDRLLYLDRYWREEEQVCADLLALLTSRRPAGVPDLRRLFPTGFDEQRRAAEIALSQGVTVLTGGPGTGKTTTVARLLALVAEQAELAGEPRPRIALAAPTGKAAARLAEAVRREMAKLDATDRARLGDLHAVTLHRLLGAKPGARFRQDRQNRLPHNVIVVDETSMVSLTLMARLAEAVRPGARLILVGDADQLASVEAGAVLADLVDGFSVRDDALVAQLRTSHRFGKVIGTLAEAIRAGDGDAVLGLLRSGEERIEFVDDEDPAPRLRAVLVPHALRLREAALLGASDVALATLDEHRLLCAHRDGPTGVLHWNRRVQAWLAEETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTGLRAVISGASGPLDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVTRAKRKVRVVGSEASVRAAIARRAVRASGLRMRLQSTGCG
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity.  When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity.  Negatively regulates the RecA-loading ability of RecBCD.
What are the official names of this protein?
RecBCD enzyme subunit RecD, Exonuclease V subunit RecD, ExoV subunit RecD, Helicase/nuclease RecBCD subunit RecD.
What is the protein family that this protein belongs to?
Belongs to the RecD family.
Protein: HIS1_JANMA
Sequence: MTQETQQLTLALSKGRIFEETLPLLEAAGIKVTEDPETSRKLILQTNDANVRVIIVRASDVPTYVQYGAADFGVAGKDVLLEHGGEGLYQPIDLNIANCRMSVAVKDGFDYESAVQQGARLRVVTKYVQTAREHFAAKGVHVDLIKLYGSMELGPLVGLADAIVDLVSTGSTLRANHLVEVERIMDISSRLVVNKAALKLKRERLQPILEAFEKASKRSS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_STRR6
Sequence: MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIDRALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXVE1_GLOTS
Sequence: MAAYLLAVAILFCIQGWPSGTVQGQVMPFMEVFKRSVCQTRETLVPVLEEHPSEIADLFKPSCATVLRCGGCCSDESLACTAVGKRSVGREILRVDPRKGTSKIEVMQFTEHTDCECRPRSRSGVDSGKRKRNPEEGEPRAKFPFV
What is the function of this protein?
Snake venom VEGFs that may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces an increase in capillary permeability after intradermal injection, in a VEGFR-2 (KDR) dependent manner (PubMed:24857790).  In addition, it provokes a drastic hypotensive effect after intravenous injection (By similarity).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase.  Also induces angiogenesis in vitro (By similarity).  Unlike other crotalid VEGFs, this protein probably interacts with VEGF receptor-2 (KDR) (PubMed:24857790).
What are the official names of this protein?
Vascular endothelial growth factor isoform GtVF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
Protein: DXR_CUPTR
Sequence: MHRITILGATGSIGESTLDVIRRHPGRYAAHALSAHRQVRKLADQCIEFRPARAVVGTAEAARELETLLRDASVATEVSYGEAALESIAADAQTDAVMAAIVGAAGLRPTLAAARAGKRVLLANKEALVMSGRIFMDAVREHGATLLPIDSEHNAIFQCLPADDPRYGRGVAKVLLTASGGPFRTRDPATLHDISPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGAPAERIEVLIHPQSIVHSMVAYTDGSVLAQLGNPDMRTPIAYGLAYPERIDAGVTPLDLTLAGGLHFEKPDLARFPCLGLAFDALRAAGVAPAVLNAANEVGVEAFLAGQVRFTDIAGIVRQVLEEAPSGPADTLEAVLAADALAREAARAGVTARAAAR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MRAY_RHOPA
Sequence: MLYWLIDLSSSFPAFNVFRYITFRTGGAMVTGALFVFMFGPWIIDNLRLRQGKGQPIRTDGPQSHLMTKKGTPTMGGLMILSGLTVGTLLWANPLNPYVWIVLAVTLGFGFVGFYDDYMKVTKQTHAGISGRTRLLIEFTIAGAACFALVWLGRAPLSSSLVIPFFKEVMLNLGWAFVVFGAFVVVGAGNAVNLTDGLDGLAIVPVMIAAASFGLISYLAGNAVFAEYLQINYVAGTGELAVLCGALLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFKLTGKRVFKMAPIHHHFEQKGWTEPQIVIRFWIIAVMLALAGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_METRJ
Sequence: MSADPRHYDIVVSPVITEKATNLTEQNKVVFRVAPKATKPQIKEAVEKLFDVKVTAVNTLVTKGKKKIFRGLRGQRSDVKKAIVTLAEGHTIDVTTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FRSA_KLEP3
Sequence: MSQANLSETLFKPRFKHPETSTLVRRFSAGKPQAMQSALSGNHVDHWYRLINRLMWIWRGVTPQEILDVQARIVMSEAERTDPELFDTVIGYRGGNWIFEWAKEAMQWQQKAGQEADPLLSGRHWLHASNLYSIAAYPHIKGDELAEQAQALANRAYEEAAQRLPGSLRELEFTIPGGSPITGFLHMPKGDGPFPTVLMCGGLDSLQTDYYNLYENYFSPLGIAMLTIDMPSIGFSSKWTLNQDTSLLHQHALRHLENVPWVDHTRVAAFGFRFGANIAVRLGYLEPQRLKAVACLGPVVHGLLVDPLHQGRVPEMYLDVLASRLGMHDASDEALRVELNRYSLKTQGLLGRRCPTPMLSGFWKDDPFSPEEESRLITSSSADGKLLEIPFNPVYRNFDHALRQIARWINHRFG
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: DASC_STRCO
Sequence: MKRSLFGRVWPNVTAVVLFIGLVFPVYWMFATAFKPTGDIISENPVWFPTDITFEHFKTATEADHFWTYVSNSLIVTVCAVVFSLVIALAGSFALARMRFKGRRGFIVGFMLAQMAPWEVMVIAIYMIVRDASMLNSLVPLTLFYMMMILPFTILTLRGFVAAVPKELEESAMVDGCTRAQAFRRVILPLLAPGLMSTSMFGFITAWNELPLVLVVNKEAESQTLPLWLTSFQTVFGDNWGATMAASSLFAIPILILFVYLQRKAVSGLTAGAVKG
What is the function of this protein?
Part of the ABC transporter complex DasABC-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake.  Responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Diacetylchitobiose uptake system permease protein DasC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APMAP_DROME
Sequence: MGLLYALRVRIMNFMIFFLLIILMPGLPPRTTFPFKDYIVTPPKDLKGALESNFHLEGAERLLEGRVYGPECLIARNNEIYTGIHGGEVIKLTSNHVTHVTKIGQPCEDIYEESRCGRPLGLAFDTQGNNLIIADAYYGLWQVDLGTNKKTLLVSPAQELAGKSINRPAKIFNGVTVSKEGDVYWTDSSSDFTIEDLVFASFANPSGRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAMRLTKYHLKGAKAGQSEVFVDGLPGLPDNLTPDAEGIWVPLVQSADSEHPNGFTLFTRFPSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLHGFDKSAATVSHVLEFQDFLFLGSPTNQYLARVKSPKAKQPTLKVRNVRVEGEGLEASIGVPPSKATPKPKAAPSTTTPKPTTTTTTTTPKPTTKTTTTTTTPKPTTTTTTKKPTTTTTTTTTTPKPTTTKPPTAKPSTTTTTTTTPKPTTTTTPTTPTPEPSKPKVKRTVPEKPAPVEEDIPSDTQPPKKEKLKVINKQGVNVEL
What is the function of this protein?
Transmembrane mucin that may be involved in cellular adhesion and the innate immune response (PubMed:8662683, PubMed:12769978).  Membrane-tethered mucins are involved in many cell surface functions and form a physical barrier around cells to regulate cell-cell and/or cell-substrate interactions, and protect against pathogens or harmful extracellular conditions (PubMed:8662683, PubMed:12769978, PubMed:11164341).  This mucin likely acts in hemocyte adhesion as it is released from hemocytes during coagulation and is also able to bind lipophorin particles which form part of the hemocyte coagulogen (PubMed:12769978).  Able to induce expression of the antibacterial proteins in the presence of GalNAc-specific lectins and so probably also functions in the innate immune response (PubMed:8662683).
What are the official names of this protein?
Adipocyte plasma membrane-associated protein Hemomucin, Protein Hemomucin.
What is the protein family that this protein belongs to?
Belongs to the strictosidine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Detected on membrane of hemocytes.
Protein: EFNA5_RAT
Sequence: MLHVEMLTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVRDRVFDVNDKVENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL
What is the function of this protein?
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor.  This signaling event requires the activity of the Fyn tyrosine kinase.  Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization.  With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance.  May function actively to stimulate axon fasciculation.  The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.  Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion (By similarity).
What are the official names of this protein?
Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Membrane, caveola; Lipid-anchor, GPI-anchor. Note=Compartmentalized in discrete caveolae- like membrane microdomains.
Protein: CYF_PICAB
Sequence: MQNRNTYDLKKKMTRLISVLVMIHIITRTSISNAYPIFAQQGYENPREATGRIVCANCHLAKKPVDIEGPQSVLPNTVFEAVVKIPYDTQMKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEIRQKMGNLYFQNYRPNQKNIIVIGPVPGQKYSELVFPILSPDPATDKEAHFLKYPIYLGGNRGRGQIYPDGSKSNNTVYSASATGRVSKILRKEKGGYEITIDNTSDGGQVVDIVPPGPELLISEGELIKVDQPLTNNPNVGGFGQGDAEIVLQDPLRVKGLLLFLASVILAQIFLVLKKKQFEKVQLAEMNL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y2794_LISIN
Sequence: MINNYIDITIRLLENILDNEADYVKEAGAKVAESIENDGVIHLFGCGHSHILTEEVFYRAGGLAAIHPILHEPLMLHEGAAASSVLERKNDYAKTFMAEEDIRSGDVMIVLSTSGRNPVPIDVAEIAREKGAFVIVITSLQYSASQKSRHTSGKRLSDTGDIVIDNGAVKGDAVLKSANFDIAFAPTSTVTGAVILQSIFAEAIEKMVNDNFTPPVFISGNVENADEHNQALVDKYNERIPLLGMNL
What are the official names of this protein?
UPF0309 protein lin2794.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: RLR37_PLAVT
Sequence: MTYRLPFVAVILFVTAKHVVLALENANWIEASKTVPSDSTQTTRVAYRRITGGFNERFLRQLEKKPGVNDKRDEERANFFEAVFKNTLFNAFGYRSDAKAKLQDPNSNIFVNLLRRIFVWWAKNKPEFNKNADMHKEAMV
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 37.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: ZN775_MOUSE
Sequence: MESGLAGSISGDGLARIKQEKPEWLLQTVASQATEKDKENIFQQQSGLPPCQTMGRPRALGSQEETGGTRWAPLPEQDAPLAARVPGTAPGPLSPSLSAGGGHFVCVDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLVRHQRHHTGERPFCCPECTRRFSQKQHLLKHQKTHSRPATHTCPECERCFRHQVGLRIHQRAHARNRLGARVNLHEMFRYAAARRWSCRLRPGSPRGHPEWVWLGLCRSWWGQHGVRTTAHSRLGPSEQRQFICNDCGKSFTWWSSLNIHQRIHTGERPYACPECGRCFSQKPNLTRHLRNHTGERPHPCSHCGRSFRQKQHLLKHLRTHLPGAQAARCTSCGQSCPSRAALRAHQRVHTAAELLRSQSAVRDGVPGSESQAEIAQSVVVKPQGPQGAKEVLCGQECETLAVPSEQRQFICNECGKSFSWWSALTIHQRIHTGERPYACPDCGRCFSQKPNLTRHRRNHTGERPYLCTACGRGFRQKQHLLKHQRVHRGTQAPHPGPEEEL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 775.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK5_HUMAN
Sequence: MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
What is the function of this protein?
Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.  Does not seem to have NDK kinase activity.  Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5.  May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
What are the official names of this protein?
Nucleoside diphosphate kinase homolog 5, NDK-H 5, NDP kinase homolog 5, Inhibitor of p53-induced apoptosis-beta, IPIA-beta, Testis-specific nm23 homolog, nm23-H5.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: PHOP_SALTU
Sequence: MMRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINIPPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGYLFELR
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence, adaptation to acidic and low Mg(2+) environments and resistance to host defense antimicrobial peptides.  Essential for intramacrophage survival of S. typhimurium.  In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG).  In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG.  Essential for transcription of spiC inside macrophages by controlling the expression of the two-component regulatory system SsrB/SpiR (SsrA) and Pir at transcriptional and post-transcriptional levels respectively.  Promotes expression of the two-component regulatory system PmrA/PmrB via activation of pmrD gene.  Is required to attenuate bacterial growth within fibroblast cells and to enhance bacterial resistance to bile in intestinal cells.  Negatively regulates prgH, which is required for invasion of epithelial cells.  PhoP uses multiple mechanisms to promote transcription and activates promoters for PAG at low (uM range) Mg(2+) concentrations (Probable).  Involved in acid tolerance.
What are the official names of this protein?
Virulence transcriptional regulatory protein PhoP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O52K1_HUMAN
Sequence: MLPSNITSTHPAVFLLVGIPGLEHLHAWISIPFCFAYTLALLGNCTLLFIIQADAALHEPMYLFLAMLATIDLVLSSTTLPKMLAIFWFRDQEINFFACLVQMFFLHSFSIMESAVLLAMAFDRYVAICKPLHYTTVLTGSLITKIGMAAVARAVTLMTPLPFLLRRFHYCRGPVIAHCYCEHMAVVRLACGDTSFNNIYGIAVAMFIVVLDLLFVILSYVFILQAVLQLASQEARYKAFGTCVSHIGAILSTYTPVVISSVMHRVARHAAPRVHILLAIFYLLFPPMVNPIIYGVKTKQIREYVLSLFQRKNM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52K1, Olfactory receptor OR11-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS19_HELAH
Sequence: MSRSIKKGPFIDDHLMKKTLKAKESKDNRPIKTWSRRSTILPEMIGFTYNVHNGRVFIPVYITENHVGYKLGEFAPTRTFKGHKGSVQKKIGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PBL26_ARATH
Sequence: MNCFSCFYFHEKKKVPRDSDNSYRRNGEVTGRDNNKTHPENPKTVNEQNKNNDEDKEVTNNIAAQTFSFRELATATKNFRQECLIGEGGFGRVYKGKLEKTGMIVAVKQLDRNGLQGNKEFIVEVLMLSLLHHKHLVNLIGYCADGDQRLLVYEYMSRGSLEDHLLDLTPDQIPLDWDTRIRIALGAAMGLEYLHDKANPPVIYRDLKAANILLDGEFNAKLSDFGLAKLGPVGDKQHVSSRVMGTYGYCAPEYQRTGQLTTKSDVYSFGVVLLELITGRRVIDTTRPKDEQNLVTWAQPVFKEPSRFPELADPSLEGVFPEKALNQAVAVAAMCLQEEATVRPLMSDVVTALGFLGTAPDGSISVPHYDDPPQPSDETSVEDSVAAEERERAVAEAMEWGVASRAHSRNPSAS
What is the function of this protein?
May be involved in plant defense signaling.
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL26, PBS1-like protein 26.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLMM_CLOBH
Sequence: MGRMFGTDGVRGIANKELTADLAYKLGKAGAFILTEGTHRSKILVGMDTRISGDMLESALVAGILSVGAEAICVGVIPTPAIAYLTRKYNADAGVVISASHNPVEYNGIKFFNKNGYKLSDELEDSIQALIRDDFKDVPVLTGENIGRKIEEDGEAIRDYIDFAKSTIKGDLKGLKVALDCANGASYITSVEAFKELGAEVHVINNKPDGININRNSGSTHPEDLMEYVVKNNCHMGLAFDGDADRCLAIDEKGNLINGDFILAICGKELKKQGRLKKNTIVVTVMSNLGLDIAMKKEEINTIKTKVGDRYVLEEMLKNDYAIGGEQSGHIIFSDYNTTGDGLVTALQLAHIVKESGKTFSELCSIMKELPQVLVNAKVPNDQKDIYLKDEEIKSEIDTITKNLDGSGRVLIRPSGTEPLVRVMLEGENQKEIDKLAHGLAKLIENKVK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CTL2_RAT
Sequence: MGKDSQHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVLLFLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNADKPFLFYFNIVKCASPLVLLEFHCPTPQICVKQCPDRYLTFLSARNSRDFDYYKQFCVPGFKNNKGVAEVLRDGECPAVIIPSKPLAQRCFPAIHASKGVLMVGNETTYEDGHGTRKNVTDLVEGAKKANKVLEARQLAMQIFEDYTVSWYWIVIGLVIAMLLSLMFIVLLRFLAGVMVWVMIVMVILVLGYGIFHCYAEYSRLRGEAGSDVSLVDLGFQTDLRVYLHLRQTWMAFMIILSILEVVIILLLIFLRKRILIAIALIKEASRAVGHVMCSMLYPLVTFFLLCLCIAYWASTSVFLSTSNVAVYKIVDDTPCPLLGKTCNPETFPLNESRQCPNGRCQFAFYGGESTYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWAMRKPDDMPAFPLFSAFGRALRYHTGSLAFGSLILAIVQIIRVMLEYLDQRLKAAQNKFAKFLMVCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIIGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNKKVAES
What is the function of this protein?
Choline transporter.
What are the official names of this protein?
Choline transporter-like protein 2, Solute carrier family 44 member 2.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.