PharMolix/UniProtQA huggingface dataset:
Protein: AMT16_ALTAL
Sequence: MSFHVNNKAVGDPLNSEDWRIKGYNPLTPPNLLQSEIPQTAKSRDTVFKAREEVIAIFQNKDAQKRLLVVIGPCSIHDPLAALEYCDRLMKLKEKYQDDLLIVMRSYLEKPRTTIGWKGLINDPDIDNSFKINKGLRISRQLFADLTEKGMPLASEMLDTISPQFLADMFSVGVIGARTTESQLHRELASGLSFPVGFKNGTDGTLDVAIDAIDSAKYPHHFLSVTKPGVVAIVGTIGNHDCFIILRGGRKGTNYDAKSIKEAREKLESEGMNPRLMIDCSHGNSEKNHMNQPKVVHAVAEQIEAGETAVIGVMIESNLKAGTQKVPKEGKAGLEYGMSITDACIDWKTTETVLAELAGAVAKRRTLLGQNGTY
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (Probable).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase AMT16, AM-toxin biosynthesis protein 16.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: Y058_NPVAC
Sequence: MFSSRKRRVAKRAFNAKSKKFPIGEVVSTRKRLKQNTNTPPHYDTSEDEDEDNYYNY
What are the official names of this protein?
Uncharacterized 6.8 kDa protein in LEF8-FP intergenic region.
Protein: RS20_STRPC
Sequence: MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NIF3L_DROME
Sequence: MLRRMNTFSGQKLAAVVKELENFAPTSWAEKWDNVGLLIEPHREKQIKKILLTNDLTEPVVKEALEKEAELIISYHPPIFKPLTRITQSHWKERVVAACLANDIALYSPHTAWDKKSGGVNDWLSKAVNIISIRPLEPELGAPPGTGSGRYIETKMELSQVVESLQKRIRNSVHVALAVGHTPKTLIQSVGICAGSGASLLKGIQADLIITGEMSHHEVLEFTHNNTTVLLCNHSNSERGFLHEFCPILAKSLNEECLVFVSEVDKDPLVTVASDINKELSAFVDVYKSTSK
What are the official names of this protein?
NIF3-like protein 1, Protein anon-35F/36A.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: O3611_CONPE
Sequence: MSRLGIMVLTLLLLVFIVTSHQDAGEKQATQRDAINFRWRRSLIRRTATEECEEYCEDEEKTCCGLEDGEPVCATTCLG
What are the official names of this protein?
Conotoxin PnMSGL-03.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FRDC_ECOLU
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPESWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_HERAR
Sequence: MKKLLIMAAGTGGHIFPGLAIADTMQARGWEVTWLGTEHGMERDLVPKSGIAMDTISFAGLRGKGLRHTVTGVLRLLASFGTCFSILARRKPGVVLGMGGYVTVPGGWMAKLRGVPLVLLNADAALLLSNKALTPIAQRVLFGFPADFGNAADKALVTGNPVRAEISALMPPAQRYAQHSGALKILVVGGSLGAQALNAALPAALALIPAEQRPLVTHQSGKKNIDDLRARYAQAGVTAEVVDFIDDMPRRYADADLVICRAGAITVSELTAAGVASVLVPLLVSTTTHQRDNAHWMEQQQAAIHLPQSELTAQGLADLLQNMTREKCKQMAEAAYANGRRDANAAIADVLEKLVKNT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HMD_METWO
Sequence: MKLAILGAGCYRTDAASGI
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
5,10-methenyltetrahydromethanopterin hydrogenase, H(2)-dependent methylene-H(4)MPT dehydrogenase, H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase, N(5),N(10)-methenyltetrahydromethanopterin hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the HMD family.
Protein: NDHL_PROM2
Sequence: METFFNNSFATLIAYIGIISTYLLVIPLFLFYWMNNRWNVMGKFERLGIYGLVFLFFPGLILFSPFLNLRPKGSGKG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: MET17_HUMAN
Sequence: MAAALKCLLTLGRWCPGLGVAPQARALAALVPGVTQVDNKSGFLQKRPHRQHPGILKLPHVRLPQALANGAQLLLLGSAGPTMENQVQTLTSYLWSRHLPVEPEELQRRARHLEKKFLENPDLSQTEEKLRGAVLHALRKTTYHWQELSYTEGLSLVYMAARLDGGFAAVSRAFHEIRARNPAFQPQTLMDFGSGTGSVTWAAHSIWGQSLREYMCVDRSAAMLVLAEKLLKGGSESGEPYIPGVFFRQFLPVSPKVQFDVVVSAFSLSELPSKADRTEVVQTLWRKTGHFLVLVENGTKAGHSLLMDARDLVLKGKEKSPLDPRPGFVFAPCPHELPCPQLTNLACSFSQAYHPIPFSWNKKPKEEKFSMVILARGSPEEAHRWPRITQPVLKRPRHVHCHLCCPDGHMQHAVLTARRHGRDLYRCARVSSWGDLLPVLTPSAFPPSTAQDPSES
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent RNA methyltransferase required to stabilize the mitochondrial small ribosomal subunit (mt-SSU).  Required for protein translation in mitochondria.
What are the official names of this protein?
Methyltransferase-like protein 17, mitochondrial, False p73 target gene protein, Methyltransferase 11 domain-containing protein 1, Protein RSM22 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Rsm22 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: COAX_BACC1
Sequence: MIFVLDVGNTNAVLGVFEEGELRQHWRMETDRHKTEDEYGMLVKQLLEHEGLSFEDVKGIIVSSVVPPIMFALERMCEKYFKIKPLVVGPGIKTGLNIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITKPSSVVGKNTVSAMQSGILYGYVGQVEGIVKRMKEEAKQEPKVIATGGLAKLISEESNVIDVVDPFLTLKGLYMLYERNANLQHEKGE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPAA_STRGD
Sequence: MLDGVVARPQEXAARYYAAGY
What is the function of this protein?
Involved in etamycin biosynthesis.
What are the official names of this protein?
Hydroxypicolinic acid-activating enzyme.
Protein: CVC1_HHV11
Sequence: MNAHLANEVQTISATARVGPRSLVHVIISSECLAAAGIPLAALMRGRPGLGTAANFQVEIQTRAHATGDCTPWCTAFAAYVPADAVGELLAPVVPAHPGLLPRASSAGGLFVSLPVVCDAQGVYDPYAVAALRLAWGSGASCARVILFSYDELVPPNTRYAADSTRIMRVCRHLCRYVALLGAAAPPAAKEAAAHLSMGLGESASPRPQPLARPHAGAPADPPIVGASDPPISPEEQLTAPGGDTTAAQDVSIAQENEEILALVQRAVQDVTRRHPVRARTGRAACGVASGLRQGALVHQAVSGGAMGAADADAVLAGLEPPGGGRFVAPAPHGPGGEDILNDVLTLTPGTAKPRSLVEWLDRGWEALAGGDRPDWLWSRRSISVVLRHHYGTKQRFVVVSYENSVAWGGRRARPPLLSSALATALTEACAAERVVRPHQLSPAGQAELLLRFPALEVPLRHPRPVLPPFDIAAEVAFTARIHLACLRALGQAIRAALQGGPRISQRLRYDFGPDQRAWLGEVTRRFPILLENLMRAVEGTAPDAFFHTAYALAVLAHLGGRGGRGRRVVPLGDDLPARFADSDGHYVFDYYSTSGDTLRLNNRPIAVAMDGDVSKREQSKCRFMEAVPSTAPRRVCEQYLPGESYAYLCLGFNRRLCGIVVFPGGFAFTINIAAYLSLSDPVARAAVLRFCRKVSSGNGRSR
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: OR85B_DROME
Sequence: MEKLMKYASFFYTAVGIRPYTNGEESKMNKLIFHIVFWSNVINLSFVGLFESIYVYSAFMDNKFLEAVTALSYIGFVTVGMSKMFFIRWKKTAITELINELKEIYPNGLIREERYNLPMYLGTCSRISLIYSLLYSVLIWTFNLFCVMEYWVYDKWLNIRVVGKQLPYLMYIPWKWQDNWSYYPLLFSQNFAGYTSAAGQISTDVLLCAVATQLVMHFDFLSNSMERHELSGDWKKDSRFLVDIVRYHERILRLSDAVNDIFGIPLLLNFMVSSFVICFVGFQMTVGVPPDIVVKLFLFLVSSMSQVYLICHYGQLVADASYGFSVATYNQKWYKADVRYKRALVIIIARSQKVTFLKATIFLDITRSTMTDLLQISYKFFALLRTMYTQ
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  Forms a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to 2-heptanone, amyl acetate, and butyl acetate.
What are the official names of this protein?
Odorant receptor 85b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or49a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGJ_THEVB
Sequence: MSHWQQITGGVTAAKGYRAAGITAGLKASGAPDLALIVSDVPAIAAGVFTTNHMCAAPVRYCRQRLQTKGTAQAILCNSGQANAATGEQGWQAVLAQADMVATALGFSPEMVLVASTGVIGQPIPLEKMRQALPTLTANLSDGGGEAAARAIMTTDLVPKQIALEAEWEGQTIRIGGMAKGSGMIHPKMATMLAFITCDAAVSPHLWQEMLQRACDRSFNQITVDGDTSTNDSVIALANGQSRTPAIAEPGAAATRLEEMLTAVCVHLAKAIARDGEGATCLIEVQVSGASDDTAARQVARTIASSMLVKSAIYGRDPNWGRIAAAAGRAGVPFDASNLAIALGGIPMMRHGQPLPFDPAAAHAYLVQQAAASTDASGQQSIDHPVVIEVSIGSGSGRGVAWGCDLSYDYVKINAEYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH4_SPHTD
Sequence: MREPTNRQGSPGPGEPRPPAQGRPRFPTWILWVALLALALWNVYTFFWPSSGARLNIPYSAFIQQVEGENVSSVTIRGQRVSGTFTEEVRVAGDQVLSPGDPVPPGTSPNEIRTGTQFQTTIPENSQTELVPLLQSHGVTVKIDQAGGSVWPSLLATIVPLFLFIGLMVYLGRSMSRGQQNVFSFGRSKARVYDAERPRVTFADVAGEEEAKAELSEVVDFLRNPMKYHAIGARLPRGILLVGPPGTGKTLLARAVAGEAGVPFFSVSASEFVEMFVGVGASRVRDLFERAKASAPSIMFVDELDAVGRQRFAGLGGGNDEREQTLNQLLVEMDGFEPHQDVIVIAATNRPDVLDPALLRPGRFDRQVTVGLPDRRGREAILRIHTRGIPVADDLDLEELAAATPGFSGADLANLVNEAALMAARKNKKIVERIDFDEALDKIVLGTERAMIMSEHDKRVVAYHEAGHAVAAHFSPGTDPLRKVSIVPRGQSLGVTIQAPEEDRFNYSRAYLLARLTVMMGGRAAEKLVFNEMTTGAQNDLKEATLLARRMVGLWGMSDEVGPVYLGMGEQHVFLGREIMQDRDVAEATLERADEAVQRLLREAMERAEQLLRKYRDKLDALAEALIAEETIGQEKITEILGAPPVPSAAPAAAADSV
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: CIAO1_LODEL
Sequence: MKLLHSIKAHDDKVWSLSSHPTLPLLATASTDKCSNIYRLSCSNASSSSSSSSPPSPPSPPSSSSPRRNFPQIAHLEDTHRRSVRSVSFKPPMGGIDHQDSNILDLPALASGSFDSTISIWGIDEPDDDNTYEIEEIIANQKEFLASPGNEWNLMAVIEGHENEIKAVDWNFSGRYLASCSRDKTVWIWETDPETLEEFECVAVLTDHTQDVKHVTWHPTRNLLASSSYDDTIRVYKQEFDDDEWSCVGMIDGHEGTVWCSKFESPKSPKAKDGTTRLVSVSDDLSARVWASKDNTGFNGGSEQLQSQSQTHLPSSIRHNAEEMVWEQESTLPQIHTHAIYSVAWSSSSGKIATAGSDGRIVVYKETNAGWEVENIQESAHGVYEINCVIWAKLDLDQEVLISGGDDGNVNIWEV
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: GATC_THEMA
Sequence: MIKVTKDLVLHLENLARLELSEDQRESLMKDFQEILDYVELLNEVDVEGVEPMYTPVEDSAKLRKGDPRFFEMRDLIKKNFPEEKDGHIKVPGIHR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PETL_PHATC
Sequence: MTVAIDYFLLVGFCFAVTSGLWIGLKSIKLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RLMN_PROA2
Sequence: MTTKQNIKRYSRKELEELMQSIGEPRFRAAQLHRWLYSDRASDFHEMTTISKSLRETLDRKYFLPQCSMSSTQCVEDSSADSTTRKFLVQLHDQEAVETVLIPAEGRNTVCVSTQVGCPLHCSFCATGYMGFTRNLNAAEIAEQVFLVQDYLDAIGCGAVTNIVYMGMGEPLLALEEVIESVGILSDTTYRLHISQKKITLSTVGLLPEIGMLARSGLTTNLAISLHSADQETRASLMPSARDYPLKELRKTLIQYTSETGQPVTLVYMLLKEINDTQEDALKLVRLARSFLCKINLIDYNPIVNIKFDSAGEQRKNIFIRTLVDAGLNVTVRKSHGSSINAACGQLAINKKLPESSTL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1109L_ASFWA
Sequence: MKVIVLLLVLAVMQPVIQSQPFPGTEELPMTRRPPKKELEYWCTYAKSCDFCWNCRHGVCKNKVFEKHPLIKKNDYIQICRVSRYNDRCSYFTDSRIRRFHIMSCTNPTYYDWFDELMQVKEDRVIDVENIKHTCLCMIATIALIGYIRKQYSRMQLQAATRLLIFLGLYVLLGILMTNIIMNLPLSTDNPMQMRRPPERDLKFWCTYAKHCDFCWTCKDGMCKNKVFSDHPIITQNDYIVNCTVSRWHDRCMYEAHFRIHYQHNMNCSQPKDLEWFIELKRHLINQDDL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-9L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: UPP_LISIN
Sequence: MANVHVINHPLVQHKLTIIRDKNTGTKAFRELVDEVATLMAYEITRDMELEDIQVETPLQTTTAKTLTGKKLGVVPILRAGLGMQDGILKLIPAAKVGHVGLYRDHDTLEPVEYFVKLPSDVEERLFIVVDPMLATGGSAIMAIDCLKKRGARNMKFMCLVAAPEGVKALQEAHPDVEIYVAGLDEKLDENGYIRPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CLCN5_MOUSE
Sequence: MAMWQGAMDNRGFHQGSFSSFQSSSSDEDLMDIPGTAMDFSMRDDVPPLDREIEGNKSYNGGGIGSSNRVMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLVKAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENHFNTSKGGELPDRPAGVGIYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWGIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons.  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RL7_HAEDU
Sequence: MSLTNEQIIEAIASKSVSEIVELITAMEEKFGVSAAAAVAAAPAAAAAEEKTEFDVVLANAGANKVAVIKAVRGATGLGLKEAKDLVESAPATLKEGISKPEAEALKKELEDAGAQVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: AEP1_LACTC
Sequence: MGSRIFSPRRLYSALSELKTETVIPKNPNKRTRDGSFRKFKRVAPAIGDSMHPFYSPNIMERAILCASEIKPELLDGQPIVPAVIKQLKTLEPALVNTRWQPQSTQGLNDWLEPFRKMRRKSSPLKLIENHEIDNVIRPSRIDSGRIPELRKFALMFEKEDAGILSASTIGSLIDRLAADQEKAVFSEEVFLYILQHYCKSSQGIASVVDSITEFLHKDIDDLKTAETLLAHVLMALRRNSIPLTPRATSAILKLIDSVSTRFHRPFCVVDFSPAVVQMTTEFYVDSGFLKESKVLFTDMVNKERCPSAQLVEKYLGLIESVCGISTSDNDFLKKFVYISNFRPIFQTTMTPRITEFLVSYCRHFDEILSLLVLVDHSKVKKQIWDLVLPQMIRRVSLLTKDSAKNCCHLTVLYQKASRFYGMPLSTKVNKAFIIQYAVNGNFAMVARLLSIIDSNAFPSFYASVLAAYDQSSAFSMEVPSSGAALKNKHQFMTSMIIPHYTEISFVGRQLALKHADTEELLEQVLKAEIAIKGRGGKSLLPQVSLKAQDCKSNYIITEAEKCLQH
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.
What are the official names of this protein?
ATPase expression protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AEP1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SCOA_XANCB
Sequence: MNQVARGAGAKRYADAKAALAGVVADGQTLAVGGFGLCGIPEALITALRDSAVSGLTVISNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVADGKETREFDGKHYVLETALQADVALIKAWRADTAGNLVFRKTARNFNPACAMAGRICIAEVEEIVELGAIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRQGDK
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit A, Succinyl-CoA:3-oxoacid CoA-transferase, OXCT A.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: HIS7_STAAS
Sequence: MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FACR5_ARATH
Sequence: MELNCVQFLRNKTILVTGATGFLAKVFVEKILRVQPNVKKLYLLVRASDNEAATKRLRTEVFEKELFKVLRQNLGDEKLNTLLYEKVVSVPGDIATDQLGINDSHLRERMQKEIDIVVNVAATTNFDERYDVGLGINTFGALNVLNFAKKCVKVQLLLHVSTAYVCGEKPGLIPEKPFIMEEIRNENGLQLDINLERELMKQRLKELNEQDCSEEDITLSMKELGMERAKLHGWPNTYVFTKSMGEMLLGKHKENLPLVIIRPTMITSTLSEPFPGWIEGLRTVDSVIIAYGKGVLKCFLVDVNSVCDMIPVDMVANAMITAAAKHAGGSGVHMVYHVGSSHQNPVTFGEIHEIAVRYFTKNPLRSRNGSLITVSKVRFIPTMALFSLYMTLRYKLPLQLLKLVDIIYPWRNGDKYGDKNRKIELVMRLVELYEPYVLFKGIFDDRNTKSLCANQKEEEIKNTEKLMFDFDPKGINWGDYLTNIHISGLVTHVLKK
What is the function of this protein?
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols (PubMed:20571114, PubMed:24005667).  Catalyzes specifically the formation of C18:0 fatty alcohol (PubMed:20571114, PubMed:24005667).  Provides the fatty alcohols required for synthesis of suberin in roots, seed coat and wound-induced leaf tissue (PubMed:20571114).  Provides the fatty alcohols required for synthesis of alkyl hydroxycinnamates in root waxes (PubMed:22797656).
What are the official names of this protein?
Probable fatty acyl-CoA reductase 5.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.