PharMolix/UniProtQA huggingface dataset:
Protein: COQ4_DROAN
Sequence: MMQRCVWRLQMPLALRRGLASGEAKNQGVSPEAEPLDSFERQYLKDRIEISPFQRVILGAGSSIAALLDPRRHDMIACLGETTGEGALENILDTMQASEEGQRIMAEKPRIHTSTIDFKLLESLPADSFGAAYVKFLKDNQVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLGMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLRPKQRRAYLKHYLPWALENGKRSKPLMPVYWEKRWEQKLQDLRAELGITVLNKV
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: FZD9_MOUSE
Sequence: MAVPPLLRGALLLWQLLATGGAALEIGRFDPERGRGPAPCQAMEIPMCRGIGYNLTRMPNLLGHTSQGEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSGGTCDNPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQEAGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVASMDPAALTGFVLVPLSCYLVLGTSFLLTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAATVPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQSLCYRKMAAGRARAKACRTPGGYGRGTHCHYKAPTVVLHMTKTDPSLENPTHL
What is the function of this protein?
Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (PubMed:24860427).  May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (By similarity).  During hippocampal development, regulates neuroblast proliferation and apoptotic cell death (PubMed:15930120).  Controls bone formation through non canonical Wnt signaling mediated via ISG15 (PubMed:21402791).  Positively regulates bone regeneration through non canonical Wnt signaling (PubMed:24391920).
What are the official names of this protein?
Frizzled-9, Fz-9, mFz3, mFz9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Relocalizes DVL1 to the cell membrane leading to phosphorylation of DVL1 and AXIN1 relocalization to the cell membrane.
Protein: FADA_COLP3
Sequence: MNEVVIVDCIRTPMGRSKAGVFRNVRAEALSAHLMKQILVRNPALNPEDIEDVIWGCVKQTKEQGFNIARNASLLAGLPKSIGGVTVNRLCGSSMEALHQASTSIMSGQGDVFLIGGVEHMGHVPMMYDVDFDPALNKNIALASGNMGLTAELLGKQHGITREMQDAFGARSHQKAHEAHLAGRWDNEIVATQGHDATGALTLVEHDEVIRPETTAESLSALRPVFDPVNGTVTAGTSSALSDGASAMLVMSAAKAKELGLTPRVKIRGMAVAGCDPATMGFGPVPATKKALKRAGLSIADIELFEFNEAFAAQALSCVRSLKVEDKMDQINLNGGAIALGHPLGCSGSRISGTLINLMEGQDVNIGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2308_BORPE
Sequence: MAGHSKWANIQHRKGRQDAKRGKLWTKIIREITVAARAGGADPDSNPRLRMAWDKATDANMPKDNIQRAIQRGAGGADGESYEEVRYEGYGIGGAAVIVDCMTDNRTRTVAEVRHAFAKHGGNLGQEGSVAFMFKHCGQFVFAPGTSEETVMEAALEAGAEDVATDEEGVIEVVCAPADFTAVRQAFEAAGLKAEVDGVVMKALNETELTGEDAVKMQKLLDVLESLDDVQEVYTNVVFDEAQ
What are the official names of this protein?
Probable transcriptional regulatory protein BP2308.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_STRC1
Sequence: MTSAQRKDDHVRLAIEQHNAHSGRNQFDDVSFVHHALAGIDRPDVSLATSFAGISWQVPIYINAMTGGSEKTGLINRDLATAARETGVPIASGSMNAYIKDPSCADTFRVLRDENPNGFVIANINATTTVDNAQRAIDLIEANALQIHINTAQETPMPEGDRSFASWVPQIEKIAAAVDIPVIVKEVGNGLSRQTILLLADLGVQAADVSGRGGTDFARIENGRRELGDYAFLHGWGQSTAACLLDAQDISLPVLASGGVRHPLDVVRALALGARAVGSSAGFLRTLMDDGVDALITKLTTWLDQLAALQTMLGARTPADLTRCDVLLHGELRDFCADRGIDTRRLAQRSSSIEALQTTGSTR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_WOLPM
Sequence: MNDQYVQKTSKDGYRSRSAYKLVEMDNKFKLFQEGQKIIDLGASPGGWSQVASQKGANVVALDIKPMNAINGVEFIQCDIINEFEILREKFKDQKFDVILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLSHGGTFVVKIFQGESDKDFCNELKKMFKTVKYFKPKSSRSESTEMYLVSLGFIGSKPSI
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_KLEP7
Sequence: MNQTLLSSFGTAFERVEHALDALREGRGVMVLDDEDRENEGDMIFAAETMTVEQMALTIRHGSGIVCLCLTEERRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIADGAKPSDLNRPGHVFPLRAQPGGVLTRGGHTEATIDLVTLAGFKPAGVLCELTNDDGTMARAPECIKFAQQHNMAVVTIEDLVAYRREHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: VE7_HPV04
Sequence: MRGAAPTVADLNLELNDLVLPANLLSEEVLQSSDDEYEITEEESVVPFRIDTCCYRCEVAVRITLYAAELGLRTLEQLLVEGKLTFCCTACARSLNRNGR
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: CITG_SHIB3
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQSLTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLALTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTLADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: GMS1_SCHPO
Sequence: MAVKGDDVKWKGIPMKYIALVLLTVQNSALILTLNYSRIMPGYDDKRYFTSTAVLLNELIKLVVCFSVGYHQFRKNVGKEAKLRAFLPQIFGGDSWKLAIPAFLYTCQNNLQYVAAGNLTAASFQVTYQLKILTTAIFSILLLHRRLGPMKWFSLFLLTGGIAIVQLQNLNSDDQMSAGPMNPVTGFSAVLVACLISGLAGVYFEKVLKDTNPSLWVRNVQLSFFSLFPCLFTILMKDYHNIAENGFFFGYNSIVWLAILLQAGGGIIVALCVAFADNIMKNFSTSISIIISSLASVYLMDFKISLTFLIGVMLVIAATFLYTKPESKPSPSRGTYIPMTTQDAAAKDVDHKH
What is the function of this protein?
Essential for the transport of UDP-galactose into the lumen of Golgi apparatus.
What are the official names of this protein?
UDP-galactose transporter, Golgi UDP-Gal transporter.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TATB_NEIMA
Sequence: MFDFGLGELVFVGIIALIVLGPERLPEAARTAGRLIGRLQRFVGSVKQEFDTQIELEELRKAKQEFEAAAAQVRDSLKETGTDMEGNLHDISDGLKPWEKLPEQRTPADFGVDENGNPFPDAANTLLDGISDVMPSERSYASAETLGDSGQTGSTAEPAETDQDRAWREYLTASAAAPVVQTVEVSYIDTAVETPVPHTTSLRKQAISRKRDLRPKSRAKPKLRVRKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SEC15_SCHPO
Sequence: MDIDVLEFVDKIASIESAGDTLDRLPQLISLACEKGQETQVYERLNELASKSAIRVEQLSAENNQDFSKSVNQLSVVRSELRSLQSLMADLNTDIQASGRDLQNMKQQLNSLSTSERFLTKYHNLVRSCMQVLHQVQYSQELLSKKQYLPTLRICSEISEVHLKRLDGLGMYSTIQQYIVTTKEAICSAVMEDLHEWLFSIRQKLPLVGKSCSQQIDEARRRWAREYKEDLVNLSSKTSISLELYLLEMMDFSPLDNEIVKISFEPLYICLQVHSYLGLLSSFRSSFERDRRRQQEFLAPKSLTTLDMAVVSEWLNSIAGFMIVEYYILQCIPNFRSYEEVQNIWTIICEKLVETILSVAFTEQSTTTIIKLKNQIVLLMHTMERFGFSVESLRNLCVELIDAFGGALILKHSVFFEEAFEKDVYAPMIVETQEEYDHYIAPYWNFPSEPFPRTMSFSKMCPLCCTTLSKFVRHFFMFLNDSVILATEVNEKAPRFYRRFILRSLVDRLKSLYPKLALSQMSQLVKNFYAFEDPLLQIEKSLVLNKPIHQIGAEASSSNNVKSTELLEGLANARKSALHEIFVKINLKIDDFLGLAEYDWTTTQVRKDVSGYLQEMVTYLQTMYLESLAGLPKHDKSYVYLETLDHLCTAMVDLLSDPSIRKVTTAAAEGFKLDVEYLESFAAQVPDQSIVNADSFIELRQCANLLLGDNMEEYLDTDKFMRDFNRLQPAVAIKFLERHINNYSANPLSNDRPKRRAIEILIATLKKR
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component sec15.
What is the protein family that this protein belongs to?
Belongs to the SEC15 family.
Protein: HIS8_CAMC5
Sequence: MKFNENLAGLVNYEAGKPIELVVREFGIEAKDVIKLASNENPFGTSPHVVEAIKSAASNAFLYPDDSYFELKEALGAKFGVGTKNIIIGSGSDQIIEFCLHAKANPQSAVLMAGVTFAMYEIYAKQVGAKIYRTRSQEHDLAEFLEIYEAHKDEISVIFLCLPNNPLGECLDTKEVYEFLKRIDEDVLVVLDCAYNEFAKFKDARKGIESSEILKFKNVIYLGTFSKAYGLGGMRVGYGIAKESIISELCKLRAPFNITTLSLKAAIEALKDEEFVTKTLENNLKQMARYEAFAREADIEFIPSYTNFITFKFDKQSASEISQNMLKKGIILRDLKSYKLNAFRITIGQSWQNDRVFEELKQNLK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TRI40_RAT
Sequence: MVPLDKDNQDICPICLDPLKEAVSTDCRHLFCRMCLIRHMDKASVSGVLSCPVCRKPCSETVLGDNYICHTHQKRVCRFCESSRHLLCEECLQSPEHRAHTELSIENAISHYKERLNRRSRKLRKDLGDLQRLKAQEEKMLQALQVDWGSHRPRTEQQNQDQTELQQKALPRHWLDQREDPPEEVAKVFNFSEAVTQLSILVSSLERMAKELDASTLKDASDLLDRSSQQKLEGLLSHVPPANSKLS
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response.  Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation.  Promotes also the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation.
What are the official names of this protein?
E3 ubiquitin ligase TRIM40, Probable E3 NEDD8-protein ligase, RING finger protein 35.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: ENO_LACCB
Sequence: MSIITDVLAREVLDSRGNPTVEVELYTEDGGFGRALVPSGASTGEHEAVELRDGDKDRFGGKGVLKAVGHVNNEIAKAVIGHDVTEQRLIDQTMIDLDGTPNKGKFGANAILGVSLAAARAAADEVGLPLYQYLGGPNAHVLPTPMMNVLNGGAHSTNTVDFQEFMIMPVGAKSVREAVRMGSETFHALQALLKSKGDITAVGDEGGFAPNLKDNEEAFELLVEAIKKAGYKPGDDIALAFDVAASEMYDAESKTYTTKWSNPDKKYTTEEWTDMIDGYINKYPIVSVEDPIDENDWEGWQTFTKKMGDKVQIVGDDLFVTNTDYLKKGIDMGVANSILIKLNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEDQLGAQSLYKGRKSFYNVKAID
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GPA3_CAEEL
Sequence: MGLCQSAEDKELTLKSKAIDKEMMQNHMSQQKVVKLLLLGAGECGKSTVLKQMRILHDHGFTAEEAEQQKSVVFNNTLQAMTAILKGMEALRMTFDKPIRENDAKFVMESHKMLQEAKVFPEELANAIQALWNDKAVQQVIAKGNEFQMPESAPHFLSSLDRIKLPDYNPTEQDILLSRIKTTGIVEVKFQMKSVDFRVFDVGGQRSERKKWIHCFEDVNAIIFIAAISEYDQVLFEDETTNRMIESMRLFESICNSRWFINTSMILFLNKKDLFAEKIKRTSIKSAFPDYKGAQTYDESCRYIEEKFDGLNANPEKTIYMHQTCATDTDQVQMILDSVIDMIIQANLQGCGL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Promotes transcription of 3',5'-cyclic phosphodiesterases pde-1 and pde-5, leading to reduced cGMP levels in sensory neurons.  This causes suppression of insulin production and signaling which leads to increased daf-16 activity and contributes to increased adult lifespan and resistance to oxidative stress.  In addition, by reducing cGMP levels, inhibits TGF-beta signaling pathways (PubMed:19489741).  Involved in behavioral response to P. aeruginosa by controlling the expression of daf-7, a member of the TGF-beta family, in ASJ sensory neurons (PubMed:25303524).  Plays a role in the avoidance response to the noxious chemical quinine in ASH sensory neurons (PubMed:14988722).
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-3 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: YCF15_HELAN
Sequence: MRVQLHCIARIHVVYLKEVDLLASLTVQSSSRRAPFLLGPQRQNVGLPPTVHH
What are the official names of this protein?
Putative uncharacterized protein ycf15.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VIRB2_BARQU
Sequence: MTETISRNIIFIVIVLLLTALVVSNPSYAANSASSLGNVDSVLQNIVTMMTGTTAKLIAIICVAAVGIGWMSGFIDLRKAAYCILGIGIVFGAPTLVSTLMGSS
What is the function of this protein?
Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB2 seems to constitute the major pilus component.
What are the official names of this protein?
Type IV secretion system protein virB2.
What is the protein family that this protein belongs to?
Belongs to the virB2 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CCR4_ASPTN
Sequence: MYSQTHQGQHVLMNGGQAHQRFGMQIPKFQSQGHHHPAQQPHHHAHHNQATHNITHQHNFSSGALAAATPHFTPSHMQNGAHANVDEDIDESMNEHWQQQLQLAAESRQASSPHYYARAVAQQTKGIQIAPSQPDGQENGTDNRNGTVKTKSKPRQGWHALDFGGQGLRALSTSLFNYVFLEKLYLNHNKLKALPQTIGQLRKLEHLDLSGNDLTELPEEIGMLTSLKKLYLFDNNIRTLPYEMGYLYRLDTLGIEGNPLNDILKSQIMKEGTKALIRYLREEMPVHLPPPDRDWVILDDTSSSTEKVTVLSHNALCDSSATSSHFGYTPSRALSWEFRRELILSELRSHDSDIVCLQEVDQGSYNGFFREQLAYNDYKGVYWPRGRAMGMQEEEAKNVDGCATFFKGSKFILLDKQMINFGQTAVRRPDAKGQDDIYNRLWQKDHIAVVVFLENRLTGSRFIVVNAHLYWDPAFKDVKLIQTAILMEEITKLSDGYAKWPPCTDKTAFRFSEAEGGGESENQPEPAPSMEYASGDQIPLFMCGDFNSSPGSAAYNLIANGRLTEEHPDLEKRLYGNLSRVGMTHPFKLKSAYGSIGELSFTNYTPDFKDILDYIWYTSNTLHVSALLGEVDKDYLQKVPGFPNFHFPSDHIALFAEFSVKGKKGKVVEADFGPQRS
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACCD_COXBR
Sequence: MNWFTKLLPKISTANKKGVPEGVWHKCPSCTAVLYRVELERNLEVCPKCYYHIRLDPRKRLAQFLDEGEQEELAEDILPVDRLKFRDSKKYKDRLSAAQKATEEKEALVVYKGNIYGNPIVAAAFNFFFVGGSMGAAVGERFAAGVEAAISERLPFVCFSTSGGARMQEGLFSLFQMAKTSAVLARLAEYKLPYISVLTDPTMGGVSASLAMLGDVIIAEPNALIGFSGPRVIEQTIRQTLPEGFQRSEFLLEHGAIDMVVDRRELKSTIASLITKLTHQPPPDLPVEESV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S11_HYDOR
Sequence: MTCCNQQSSQPKTTTNCAGNSCYKKTWSDHRGTIIERGCGCPQVKSGIKLECCHTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Toxin A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SARZ_STAAC
Sequence: MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDKK
What is the function of this protein?
Activates transcription of virulence factors alpha- and beta hemolysin genes (hla and hlb).  Also, activates RNAIII expression, a central regulator transcribed from the agr locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_ALIB4
Sequence: MATYLEFEEKIKKIEEDIIVAKTKADEPAVDILEKKLEKEVEKTFKNLNDYQKLQLARHPDRPYALDYISGLLKNAYEVHGDRHYVDDHAIVCYFGFIDNQKVLVIGEQKGRGTKEKLQRNFGMPSPEGYRKALRAAKMADKFQIPILMLVDTPGAYPGIGAEERNQSEAIAKNLFEFADLTTPTISVVIGEGGSGGALAISVADKLAMMRYSVYAVISPEGCSAILWNDPTKVETAANALKITAENLKELNLIDDVINEPLIGAHRQKEQAIFALKEYFIKSLAELKKLTPQERLDKKYQKLMNLGSFTK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_ECO8A
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_SPAEH
Sequence: MGLSDGEWQLVLNVWGKVEGDLAGHGQEVLIKLFKNHPETLEKFDKFKHLKSEDEMKGSEDLKKHGNTVLTALGGILKKKGQHAAEIQPLAQSHATKHKIPIKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TPIS_MYCUA
Sequence: MSRKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYYDKVDVTVIPPFTDLRSVQTLVDGDKLRLTYGGQDLSQHDSGAYTGDISGAFLAKLGCSFVVVGHSERRTYHNEDDALVAAKAAAALKHDLTPIVCIGEHLDVREAGNHVAHNVEQLRGSLSGLSAEQISKVVIAYEPVWAIGTGRVAGAADAQEVCAAIRSELGSLASPQIADAVRVLYGGSVNAKNIGELIAQADVDGGLVGGASLDGEQFATLAAIAAGGPLP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_CUPNH
Sequence: MSYLLDPSRKTITIPKLQAMRDAGEKIAMLTAYDSSFAALLDYCGVEMILVGDSLGNVMQGQQTTLPVTLEQMAYHTECAARGNQTSLLLTDLPFGTYPTPEAAFASAVTLMKAGAQMVKLEGGDWLAPIVKFLVERSIPVCAHIGLTPQSVHALGGFKVQGKTNAGAAQLKRDALALQAAGAQVVLMEAVPAALAGEITQSLTVPTIGIGAGADCSGQVLVLQDMLNVYPGRKAKFVRNFMDGQTSIEAAVRAYVAAVKDGSFPAAEHTFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.