PharMolix/UniProtQA huggingface dataset:
Protein: XK_RAT
Sequence: MKFPASVLASVFLFVAETMAALYLSSTYRSAGDRMWQALTLFFSLMPCTLVQLTLLFVHRDLSRDRPLVLLMHLLQLGPLYRCCEVFCIYCQSDQNEEPYVSITKKRQMPKDGLSEEVEKEVGQSEGKLFTHRSAFSRASVIQAFLGSAPQLTLQLYITVLEQNITTGRFIMVLSLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVIVLVLFTSVLKIWVVVVILVNFFSFFLYPWILFWNSGSPFPENIEKALTRVGTTIVLGFLTLLYAGINMFCWSAVQLKIDNPELISKSQNWYRLLIYYMMRFVENSVLLLLWFFFKTDIYMYVCAPLLILQLLIGYCTSILFMLVFYQFFHPCKKLFSSSVSESFSACLRCVCWSSARRKSTEPVGRIDTDLKACTDQGAQPSTSKLTPEATEIWTAVDLCST
What is the function of this protein?
Recruits the lipid transfer protein VPS13A from lipid droplets to the endoplasmic reticulum (ER) membrane.
What are the official names of this protein?
Endoplasmic reticulum membrane adapter protein XK, Membrane transport protein XK, XK homolog, XK-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DNAK_BACAN
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDYTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEELSAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQAITIQSSSGLSDEEVERMVQEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRAKKDALQEIVQQLTVKLYEQAQAAAGQAEGAEGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ATPD_YEAST
Sequence: MLRSIIGKSASRSLNFVAKRSYAEAAAASSGLKLQFALPHETLYSGSEVTQVNLPAKSGRIGVLANHVPTVEQLLPGVVEVMEGSNSKKFFISGGFATVQPDSQLCVTAIEAFPLESFSQENIKNLLAEAKKNVSSSDAREAAEAAIQVEVLENLQSVLK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit delta, mitochondrial, F-ATPase delta subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: SYN_GEOMG
Sequence: MSARIRIRNALAGEGLGNEIMVKGWVRTIRTGKEVAFLALNDGSCFANLQVVAEPGLATFADVCAIGTGAAVAVRGRLVDSPASGQCYELHADEVAVIGLADESYPLQKKRHSFEYLRSIAHLRPRSNTFGAVFRVRSSVAQAVHRFFAERGFLYVHTPIITTSDCEGAGEMFRVTTLDPAAPPLLEGEVDFSRDFFAAQAGLTVSGQLEGELFAQAFSDIYTFGPTFRAENSNTPRHAAEFWMIEPEMAFADLMADAALAEEFFRYLCRHVLDACGEDMAFFNDHIDKGLIARVEQVANSSFAIMEYGEAIERLKKATVTFEYPVEWGLDLQTEHERYLTEQVVGGPVFVINYPKHIKAFYMRVNDDNKTVAAMDLLVPKVGEIIGGSQREERLPVLEGRMAEVGVNPEGLWWYLDSRRWGSTPHAGFGLGFERLIMYLTGMENIRDVIPFPRTPRHAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK2_NOSS1
Sequence: MAKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAFAKNGDTLVGQIAKRQAVMNPENTFYSVKRFIGRRYDEVTNEATEVSYKVLSSGGNVKVDSPGAGKQFAPEEISAKVLRKLVEDASKYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGIEVMRIINEPTAASLAYGFDKKSNETILVFDLGGGTFDVSVLEVGDGVFEVLATSGDTHLGGDDFDKKIVDFLAEQFRKDEGIDLRKDKQALQRLTEAAEKAKIELSSVTQAEINLPFITATQDGPKHLDMTLTRAKFEELCADLIDRCRIPVEQALRDAKLKKENIDEVVLVGGSTRIPAVQQLVKNLLGREPNQTVNPDEVVAVGAAIQAGVLGGEVTGILLLDVTPLSLGVETLGGVMTKIIPRNTTIPTKKSEVFSTAVDGQTNVEIHVLQGEREFANDNKSLGTFRLDGIPPAPRGVPQIEVVFDIDANGILNVTAKDKGTGKEQSISITGASTLDKTDIDRMVREAEQNASSDKERREKIERKNQADSLAYQAEKQLQELGDKVPEADKTKVEGLVKDLREAVAKEDDEQIKKLTPELQQALFAVGSNIYQQAGGGAAPGAAPQDGGTTSSDGGDDVIDADFTETK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK2, HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SHCAF_HUMAN
Sequence: MFGFHKPKMYRSIEGCCICRAKSSSSRFTDSKRYEKDFQSCFGLHETRSGDICNACVLLVKRWKKLPAGSKKNWNHVVDARAGPSLKTTLKPKKVKTLSGNRIKSNQISKLQKEFKRHNSDAHSTTSSASPAQSPCYSNQSDDGSDTEMASGSNRTPVFSFLDLTYWKRQKICCGIIYKGRFGEVLIDTHLFKPCCSNKKAAAEKPEEQGPEPLPISTQEW
What is the function of this protein?
Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288).  Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells.  Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).
What are the official names of this protein?
SIN3-HDAC complex-associated factor, Protein FAM60A, Tera protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SINHCAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14_ALCBS
Sequence: MAKESMKNREAKRTKLVQRFAAKRSALKAIIQDPNAEPEAKWDAQLQLQKLPRDSSPVRQRNRCRLTGRPHGYYRKFGLSRIKLREAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CNKR3_MOUSE
Sequence: MEPVTKWSPKQVVDWTRGLDDCLQPYVHKFEREKIDGEQLLKISHQDLEELGVTRIGHQELVLEAVDLLCALNYGLETDTMKNLVLKLRASSHNLQNYISSRRKSPAYDGNTSRKPPNEFLTSVVELIGAAKALLAWLDRAPFTGITDLSVTKNKIIQLCLDLTTAVQKDCLIAEMEDKVLNVVKVLNGICDKTMRSTTDPVMSQCACLEEVHLPNVRPGEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNRQTVVGWQLKNLVRKLRENPTGVVLLLKKRPTGSFSFTPAPLKNLRWKPPLVQTSPPPTTTQSPESTMDASLKKEKPAILDLYIPPPPAVPYSPRDENVSFGYRGHSKSKQPLPVRKGSESPNSFLDQESQRRRFTIADSDQLPGYSVETNVLPTKMRGKTPSYGKPRPLSMPADGNWMGIVDPFAKPRGNGRKGEDALCRYFSNERITPITEESASPMYRFSRPLTERHLVRGADYIRGSRCYINSDLHSSATIPFQEEGSKKKSASSSAKASSGEPSLLVSWLTRLKLLTH
What is the function of this protein?
Involved in transepithelial sodium transport.  Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression.  Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
What are the official names of this protein?
Connector enhancer of kinase suppressor of ras 3, Connector enhancer of KSR 3, CNK homolog protein 3, CNK3, CNKSR family member 3, Maguin-like protein.
What is the protein family that this protein belongs to?
Belongs to the CNKSR family.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane; Peripheral membrane protein.
Protein: YCF48_GLOVI
Sequence: MGKWSGLGLGLLLLVLAGCGAPPLERDEWKVIPTGLSDKADLLDIAFVDDKNGWAVGSRSTLLRTADGGESWTAVPVKLDSDSRFLSVSFDGKNGWIGGEPKRLLRTVNGGASWTSITLDQRLPGSPLKVYALGADTAEVVLNSGLVIKTVNGGKNWQVVTPASAGGIRSAERVADGSYWVVSTRGGSYLQWKPGDPQWTNYERTSSRRIQAMGFSSGKAGWMINQGGEMQFTANQGETWTPGRSVILNGLSLLDADYTAADKKIWAAGGGGTLIVSADDGQNWKAEEVPGIKGSLLNVEFIGNKGFVLGQNGVLLKYRGAAD
What is the function of this protein?
A factor required for optimal assembly of photosystem II (PSII), acting in the early stages of PSII assembly.  Also plays a role in replacement of photodamaged D1 (psbA).  Assists YidC in synthesis of chlorophyll-binding proteins.
What are the official names of this protein?
Photosystem II assembly lipoprotein Ycf48.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side. Note=Associated with a PSII precusor complex on the periplasmic side of the membrane.
Protein: GAL1_SALAR
Sequence: MNLKEKTRALFAEVFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRTVRVIAADYDNQVDEFSLDAPIVTHDSQQWSNYVRGVVKHLQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVACELDPVVAKRVRHVLSENARTVEAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVEIVKATIGDKGGVRMTGGGFGGCIVALIPEDLVPAVQQAVAQQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CLOBA
Sequence: MNEIIRAIEAEQLRTDLPNFKIGDNVKVYVKVTEGTRERVQMFEGTVIKKQNGGLRETFTVRRVAYGCGVERTFPMHAPIIEKIEISRRGKVRRAKLYYLRDRVGKAAKVKELLTR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: VU10_HHV7J
Sequence: MAIAESGAFEINVNLGKSIASIQKNPIIYMRRHLSFYVELLKFIIHQYEQCFLPPKGTILYHNGLIELNTLIIDLNQQITSKQQIYSWTSITLPKIFSTKELYFIVASPESENITLNPAVTKGGWLSGSFSFPLSLSCAYALTGVSSTIYMLPFIPYKFPMTYVDFSTLRTYEVTSEYGSIQIIKQRNFLFLGIIRDLSWKSQRDNKNFILKAMFVGNWLGIQIPEAFALRLFNNTRFSIQDFEFSINIQNINLTRDNKILGSLSTVSCDQMPPNLSPENLPNYLVIQFELVSTLANPDHLLFSCNPKLFFTGDILNSAINLQHSPNHYELTVYAPHNLHFYPSCFHIVTLPIQFSSRNDRQMLVSSYPNEGYFEVQMCPWVQNSPLQIVIKSFSKNLVLPQGTPIAILLYMEKMTTGKNSLRDQELKINKDITRIGNVNLPKENFLHYNS
What are the official names of this protein?
U10 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U10 family.
Protein: DXS_MARMS
Sequence: MFEEIPTARPDTPLLDEVNSPADLRAFKKEQLPALVRELREFMLYSVGQTGGHFGAGLGVVELTVALHYLYNTPEDRIVWDVGHQAYPHKILTGRREALLNIRQENGISGFPKRDESEYDTFGVGHSSTSIGAALGMSLAARQLKTGRKAVAIIGDGAMSAGMSFEALNHAGDVKADMLVILNDNEMSISKPVGALSSYFARIWASKTYDNIREGGRKVFSGLPSALELARKAEEHMKGMVSPGMMFEELGFNYIGPIDGHDMDHLLTTIANLKDRKGPQFLHVITKKGKGFEPAEGDPIGYHAINKIEPDPKPNVDKSKLPKYCNVFGKWVCDAAEQDDKLVAITPAMKEGSDLIEFADRFPERYFDVAIAEQHAVTLAAGMACDGIKPVVAIYSTFLQRAYDQLIHDVALQNLDVLFAIDRAGLVGEDGPTHAGVYDLSYLRCIPNMVVMAPSDEDECRKMLQTGYEYKGPAAVRYPRGTGQGVDIESTLSTLKIGKSRTLRTGQSGIVICGFGRPTYDALKAANTLDATLLDMRFVKPIDEETLLTHRDAKLIVTVEENAIMGGAGSAVSELLIANNINIPTLHLGLPDQYEEHASHASMLKRVGLDADGIQKSIELKLTHL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MMPS2_MYCTO
Sequence: MISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPKRVTYEVFGPAKTAKIAYLDPDARVHRLDSVSLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRALTSCQVSSG
What are the official names of this protein?
Probable transport accessory protein MmpS2.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YFBV_SALHS
Sequence: MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMTRYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFB_BURPS
Sequence: MQFPESWLRTFVDPQLTTDELSHALTMAGLEVESLRPAAPPTEKIVVGRVLEVVKHPDADKLNVCQVDAGTGATLQIVCGAPNVAPGIKVPVALVGAKLPPAEEGGAPFAIKLSKLRGVESQGMLCSARELKLSEDHSGLMILPEGTPVGQDIREALNLDDTVFEIKLTPNKADCLSVFGIARETAAITGAPLAAPDIRPVLAELTETLPVKISAPDLCGRFSGRVIRGVNARAKTPHWMVERLERAGQRSVSALVDISNYVMFELGRPSHVFDLDKIHGGIDVRWGKRGESLKLLNGNTIELDETVGVISDGAQVESLAGIMGGDSTAVTLDTTNIYLEAAFWWPDSIRGRARKYNFSTDAAHRFERGVDYSTTVEHVERITQLILDICGGQAGPVDDQIVSLPQRAPVSMRASRANRIIGVEIGEDEIAQIFTRLGLAFERDGDVFRVTPPPHRFDIEIEEDLIEEVARIYGFEKIPARPPVAKSEMRATDETRRSVHAIRHALAARDYAETVNFSFVDAEWERDFAGNDNPVRLLNPIASQLSVMRTTLFGSLVGVLRHNLNRRAERVRVFEAGRVFVADPSVKAGELAVEGYAQPKRIGALAYGPVVEEQWGTATRQVDYFDVKGDLEALLAPVPARFVKAEHPALHPGRSARIEVDGHAVGWIGELHPRLMQKYELPHAPVMFEIDTDALVARALPAPSEVSKFPPVRRDIAVVVDQKVEVQALFDEMKKALADDACKFVQRVALFDEFRAKSNTSGGLSAHEKSLAFRVTLQDAAGTLQDETVDQAIQTLVDRMARVYGARLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_SALHS
Sequence: MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLIPHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHREKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLNTDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDGEKRALREKVAAA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: SECA1_COREF
Sequence: MFGLSKMLRVGEGRAVKRLQKIADQVIALEDQYANLTDEELKAKTEEFKDRLAQGETLDDIFLDAFATAREASWRVLGQKHYKVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLSVGVILSELRPAERKVAYDCDITYGTNNELGFDYLRDNMARSLNDLVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYNVFAQIVPQLTRDIHYEVDHRKKTVGIKEEGVEKVEDLLGIENLYAPEHSQLVSYLNNAIKAEELFERDKDYIVRNGEVMIVDGFTGRVLAGRRYNEGMHQAIEAKEKVEIKNENQTLATVTLQNYFRLYEKLSGMTGTAETEAAELHQIYKLDVIQIPTNRENQRDDLTDLVYKTQEAKFAAVVDDIAERIANGQPVLVGTVSVERSEYLSQLLTRRGIKHNVLNAKHHEQEAQIVAQAGLPGAVTVATNMAGRGTDIVLGGNPDILLDIKLRERGLDPFEDEEAYQVAWEEELPKMKQRCEERAEKVREAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGATRFYLSMRDDLMVRFVGPTMENMMNRLNVPDDVPIESKTVTNSIKGAQAQVENQNFEMRKNVLKYDEVMNEQRKVIYSERREILESSDISHYIKNMVDETISAYVAAATANGYVEDWDLDKLWNALEALYGPTFTWQSLVDGSEYGAPGELSAEDLRTALLEDARAEYAKLEEAVTALGGEAQMRNIERMVLMPVIDQKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNAMKEAIKEETVRQLFLMRKQFVKQDEEANA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: UBIA_VIBVY
Sequence: MSVEKAKAYWQLMRMDRPIGTLLLLWPTLWALIIAAEGTPDWHVLLVFVLGVVLMRSAGCVINDFADRKVDGHVKRTQQRPLPSGRVTAKEAVILFLLLGISSFLLVLTMNPLTIQLSFAGIVLAFIYPFMKRYTHLPQLFLGLAFSWAIPMAWAAQANELPWVVWFVFAINALWTIAYDTQYAMVDRDDDIQIGVKSTAILFGRHDKLIIGLLQLLTLVMLVWLGLHYQLGQSFYWSVLAAGALFVYQQHLIRHRQRELCFQAFLNNNYVGMVLALGLFVAFW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSTT_HAEIE
Sequence: MNTSRLFSLLFQGSLVKRIAAGLVLGIVVALISAPLQETIGFNLAEKVGVLGTIFVKALRAVAPILIFFLVMAALANRKIGTKSNMKEIIVLYLLGTFLAAFVAVIAGFAFPTEVVLAAKEDSSSAPQAVGQVLLTLILNVVDNPLNAIFKANFIGVLAWSIGLGLALRHASDATKNVLSDFAEGVSKIVHVIISFAPFGVFGLVAETLSDKGLVALGGYVQLLAVLIGTMLFTAFVVNPILVYWKIRRNPYPLVWTCVRESGVTAFFTRSSAANIPVNIELAKRLNLDEETYSVSIPLGANINMAGAAITITILTLAAVHTLGLEVSFVSALLLSIVAALCACGASGVAGGSLLLIPLACSLFGISDDVAAQMIGVGFIIGILQDSTETALNSSTDVLFTAAVCMEEERKNAA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_CLOD6
Sequence: MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAASIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSHIEVVVKEKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Z_TACVF
Sequence: MGNCNRTQKPSSSSNNLEKPPQAAEFRRTAEPSLYGRYNCKCCWFADKNLITCSDHYLCLRCHQIMLRNSELCNICWKPLPTSIRVPLEASAPDL
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: ATPG_MYCSJ
Sequence: MAATLRELRGRIRSAGSIKKITKAQEMIATSRIAKAQARVEAARPYDREITNMLTELATASALDHPLLVQRENPRRAGVLVVSSDRGLAGAYNANVFRRSEELFSLLREEGKEPVLYVVGRKALSYYSFRNWDVTESWSGFSERPEYEHAQEIGETLVKAFMAGVDDEGDDAGADGILGLDELHIVFTEFRSMLSQSAIARRIAPMVVEYSEEDTNEPHTLFSFEPSAETLFDALLPRYVSTRIFAAMLEAAASESASRRRAMKSASDNADDLIKDLTLMANRERQSQITQEISEIVGGANALADAAKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QUEC_SALPK
Sequence: MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEIDVARALALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNILFLTLVAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPLMWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKSAVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MCRZ_METJA
Sequence: MAYKPQFYPGNTLIAENRRKHMNPEVELKKLRDIPDDEIVKILGHRNPGESYKTVHPPLEEMDFEEDPIKDIVEPIQGAKEGVRVRYIQFADSMYNAPAQPYDRARTYMWRFRGIDTGTLSGRQVIEMRELDLEKISKNFLIDTEFFDPATCGIRGATVHGHSLRLDENGLMFDGLQRYIYDEKTGHVLYVKDQVGRPLDEPVDVGEPLPHDYLAKITTIYRKDNIGMREDKEALEVVQIIHEARTKGGFGLEVFKKDLKKRLGEE
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit gamma, MCR II gamma, Coenzyme-B sulfoethylthiotransferase gamma.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase gamma subunit family.
Protein: ILVD_SHEB9
Sequence: MPKLRSATSTEGRNMAGARALWRATGVKDNDFGKPIIAISNSFTQFVPGHVHLKDMGSLVASAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDKLIKLDLVDAMVAGADSNVSDEDSAKIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRRELFLEAGRRVMALAKRYYHQDDESALPRNIANFKAFENAMTLDIAMGGSSNTVLHLLAAAQEADVDFTMADIDRMSRLVPHLCKVAPSTPKYHMEDVHRAGGVMGILGELDRAGLLHTDVFHVAADNDGTPGSGTLKSVLAQYDVMQTQDEKVKHFFMAGPAGIPTTKAFSQDCRWPSLDNDRQEGCIRSREFAFSQEGGLAVLSGNVAENGCIVKTAGVDESNLTFVGSARVYESQDDAVAGILGGEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSRGLGKACALITDGRFSGGTSGLSIGHVSPEAAAGGTIALIENGDRIEIDIPKRSIKLAVSDVELNARREKMHSLGPMAWKPIGRQRYVSLALKAYAMLATSADKGAVRDRSKLED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.