PharMolix/UniProtQA huggingface dataset:
Protein: VPS10_YEAS7
Sequence: MILLHFVYSLWALLLIPLINAEEFTPKVTKTIAQDSFEILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRGCYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGEFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQFIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSSFKMAYMPTQLRHSMQGEIYEDAMGRIILLMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINLYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYFNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLSSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDALPEGNEENIDRPDSTAPSNENQ
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.  Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein PEP1, Carboxypeptidase Y receptor, CPY receptor, Carboxypeptidase Y-deficient protein 1, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10, Vacuolar protein sorting-associated protein 10, Vacuolar protein-targeting protein 1.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: EXO5_DEBHA
Sequence: MIRPGKVLVLNFLKRSLSNLATFKGSEINTKKYDLKLPNNSDSNKQYFTLDEKLKVIQYTDANEESIIDEFILPLSSGAKASDTYQKTNLSKMRNLLTTFHIDEGESLPLSKPGYIKETPFEYHSKYNSDTSYVSIPRLSVTKLLTFQWCELREFYTIFSGSPVKKETKEMKLGTEAHLKLELETHNLIDVEDIERITDEFVEKKIDSSKRHINTLADPDDILLAKDDLSKLTELLHGAIPESSMANEWMSKIISRLFTLINTSEAREVLVHGYLDFQTSHFTSNLHDFQLNQSNLVLVSGVVDYLKLFNPHDKTDYSMFEDIQDHVEFTYSSQRKHQWIDLSQFLKDIDPIIKEYSDTYKIAITDVKTRSWNKLPQQESVLQAAKLQVEYYRNMFGILAGEFDDIEIGYEMLLENAKRRNLDVDKPISIKSALALLKANHTIILKDYVKLANGEAIGFESFDRFSQERYLNQGSEYDFTKVLEGTNREDYISQIKASDKDGFDFDEILTSDILKAWKIPLTLRYFAARSSQLFHLCKPFLSDSLSIEYHNVKKNDQCFHTNYYNYNANEIDEVTAKASAFWNGTRPPIPVQDLSKCNYCDFSSRCVIPNPHKNVPGSYGSVGSKMKHFI
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MUTS2_BACVZ
Sequence: MQQKVLSSLEFHKVKEQITAHAASSLGREKLLQLKPLTDLSDIQKQLDEVEEASAVMRLRGHAPFGGLTDIRSALRRAEIGSVLTPAEFTELSGLLYAVKQMKHFISQMTEDGVGIPLIQAHAEELITLGDLEREINSCIDDHGEVLDHASPALRGIRTQLRTLESRVRDRLESMLRSSSASKMLSDTIVTIRNDRFVIPVKQEYRSSYGGIVHDTSSSGATLFIEPQAIVDMNNSLQQAKVKEKQEIERILRMLTEHTAEHTQEIAQDVEVLQTLDFIFAKARYAKAMKATKPLMNGDGFIRLKKARHPLLPQDQVVANDIELGGDYSTIVITGPNTGGKTVTLKTLGLLTIMAQAGLHIPADEGSEAAVFDNVFADIGDEQSIEQSLSTFSSHMVNIVNILKDVSENSLVLFDELGAGTDPQEGAALAMSILDEVHRTNARVLATTHYPELKAYGYNRQGVMNASVEFDIETLSPTYKLLIGVPGRSNAFEISRRLGLPEHIIGQAKSEMTAEHNEVDLMIASLEKSKKRADEELSETESIRKEAEKLHKDLQQQIIELNAQKDKMMEEAEQKAAEKLEAAANEAEQIIRELRSIKQEHRSFKEHELIDAKKRLGDAMPAFEKSKQPERKTEKKRELKPGDEVKVLTFGQKGALLEKTGEKEWNVQIGILKMKVKEKDLEFLKSAPEPKKEKAITAVKGKDYHVSLELDLRGERYENALSRVEKYLDDAVLAGHPRVSIIHGKGTGALRKGVQDLLKNHRSVKSSRFGEAGEGGSGVTIVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RCBT1_HUMAN
Sequence: MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN
What is the function of this protein?
May be involved in cell cycle regulation by chromatin remodeling.
What are the official names of this protein?
RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1.
Protein: RS20_ECO81
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: 1A1L2_HUMAN
Sequence: MSHRSDTLPVPSGQRRGRVPRDHSIYTQLLEITLHLQQAMTEHFVQLTSRQGLSLEERRHTEAICEHEALLSRLICRMINLLQSGAASGLELQVPLPSEDSRGDVRYGQRAQLSGQPDPVPQLSDCEAAFVNRDLSIRGIDISVFYQSSFQDYNAYQKDKYHKDKNTLGFINLGTSENKLCMDLMTERLQESDMNCIEDTLLQYPDWRGQPFLREEVARFLTYYCRAPTRLDPENVVVLNGCCSVFCALAMVLCDPGEAFLVPAPFYGGFAFSSRLYAKVELIPVHLESEVTVTNTHPFQLTVDKLEEALLEARLEGKKVRGLVLINPQNPLGDIYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDESITFHSILSMKSLPDSNRTHVIWGTSKDFGISGFRFGALYTHNKEVASAVSAFGYLHSISGITQHKLCQLLQNTEWIDKVYLPTNCYRLREAHKYITAELKALEIPFHNRSSGLYVWINLKKYLDPCTFEEERLLYCRFLDNKLLLSRGKTYMCKEPGWFCLIFADELPRLKLAMRRFCDVLQEQKEALIVKQLEDAMRE
What are the official names of this protein?
Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2, ACC synthase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: ANGR_VIBA7
Sequence: MNQNEHPFAFPETKLPLTSNQNWQLSTQRQRTEKKSITNFTYQEFDYENISRDTLERCLTTIIKHHPIFGAKLSDDFYLHFPSKTHIETFAVNDLSNALKQDIDKQLADTRSAVTKSRSQAIISIMFSILPKNIIRLHVRFNSVVVDNPSVTLFFEQLTQLLSGSPLSFLNQEQTISAYNHKVNNELLSVDLESARWNEYILTLPSSANLPTICEPEKLDETDITRRCITLSQRKWQQLVTVSKKHNVTPEITLASIFSTVLSLWGHQKYLMMRFDITKINDYTGIIGQFTEPLLVGMSGFEQSFLSLVKNNQKKFEEAYHYDVKVPVFQCVNKLSNISDSHRYPANITFSSELLNTNHSKKAVWGCRQSANTWLSLHAVIEQEQLVLQWDSQDAIFPKDMIKDMLHSYTDLLDLLSQKDVNWAQPLPTLLPKHQESIRNKINQQGDLELTKELLHQRFFKNVESTPNALAIIHGQESLDYITLASYAKSCAGALTEAGVKSGDRVAVTMNKGIGQIVAVLGILYAGAIYVPVSLDQPQERRESIYQGAGINVILINESDSKNSPSNDLFFFLDWQTAIKSEPMRSPQDVAPSQPAYIIYTSGSTGTPKGVVISHQGALNTCIAINRRYQIGKNDRVLALSALHFDLSVYDIFGLLSAGGTIVLVSELERRDPIAWCQAIEEHNVTMWNSVPALFDMLLTYATCFNSIAPSKLRLTMLSGDWIGLDLPQRYRNYRVDGQFIAMGGATEASIWSNVFDVEKVPMEWRSIPYGYPLPRQQYRVVDDLGRDCPDWVAGELWIGGDGIALGYFDDELKTQAQFLHIDGHAWYRTGDMGCYWPDGTLEFLGRRDKQVKVGGYRIELGEIEVALNNIPGVQRAVAIAVGNKDKTLAAFIVMDSEQAPIVTAPLDAEEVQLLLNKQLPNYMVPKRIIFLETFPLTANGKVDHKALTRMTNREKKTSQSINKPIITASEDRVAKIWNDVLGPTELYKSSDFFLSGGDAYNAIEVVKRCHKAGYLIKLSMLYRYSTIEAFAIIMDRCRLAPQEEAEL
What is the function of this protein?
Bifunctional protein that plays an essential role in virulence.  Plays a role in both production of the siderophore anguibactin and regulation of iron transport genes.
What are the official names of this protein?
Anguibactin system regulator.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CYB5_NEUCR
Sequence: MSAEFTYQDVAEHNTKKDLYVVIHDKVYDITKFVDEHPGGEEVLLDVAGQDSTEAFEDVGHSDEAREALEPLLVGTLKRQAGDPKPKAPLPSSLAPAAQTGTATGLGIGLYAVLVLGGLAGFAAYQYLQAQQGATAPSA
What is the function of this protein?
Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
What are the official names of this protein?
Probable cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: EABF_STRCO
Sequence: MHRGSLSRGHTSAVLAAVVAALAALAALLVATTPAQAAGSGALRGAGSNRCLDVLGGSQDDGALLQLYDCWGGTNQQWTSTDTGRLTVYGDKCLDVPGHATAPGTRVQIWSCSGGANQQWRVNSDGTVVGVESGLCLEAAGAGTANGTAVQLWTCNGGGNQKWTGLTGTPPTDGTCALPSTYRWSSTGVLAQPKSGWVALKDFTTVTHNGRHLVYGSTSSGSSYGSMVFSPFTNWSDMASAGQNAMNQAAVAPTLFYFAPKNIWVLAYQWGSWPFIYRTSSDPTDPNGWSAPQPLFTGSISGSDTGPIDQTLIADGQNMYLFFAGDNGKIYRASMPIGNFPGNFGSSYTTIMSDTKANLFEGVQVYKVQGQNQYLMIVEAMGANGRYFRSFTASSLSGSWTPQAASEGNPFAGKANSGATWTNDISHGDLVRDNPDQTMTVDPCNLQFLYQGKSPNAGGDYNSLPWRPGVLTLRR
What is the function of this protein?
Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall.  It has a specific arabinofuranose-debranching activity on xylan from gramineae.  Acts synergistically with the xylanases and binds specifically to xylan.  From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well (By similarity).
What are the official names of this protein?
Extracellular exo-alpha-L-arabinofuranosidase, ABF, Arabinosidase, Arabinoxylan arabinofuranohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydr olase 62 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPP_PYRAE
Sequence: MPVRIIDHVYAQYLLTKLRDKNTGSIEFRKGLVRLGRIIGYELAKTFPVKYVEIETPLGKAVGVDIIGLDKVVIVQVLRAAMPLVEGLVKAFPQARLGVVAAKRREEGGVVDVDIFYSKVPKIAEDDVVIVADPMLATGITMSRVIEEVYRAGNPGRLIVVSVIATPMGIERVLSRWPSAEIYAVAVDPTLNDKAFIVPGLGDAGDRAFAT
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PFKA_ECOSE
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 1, ATP-PFK 1, Phosphofructokinase 1, 6-phosphofructokinase isozyme I, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF_STRGB
Sequence: MPIATPEVYNEMLDRAKAGKFAYPAINVTSSQTLNAALRGFAEAESDGIVQISTGGAEFLGGQYSKDMVTGAVALAEFAHIIAEKYPVNIALHTDHCPKDKLDGYVRPLLALSKKRVEAGLGPLFQSHMWDGSAEPLADNLAIAQELLETARAAQIILEVEITPTGGEEDGVSHEINDSLYTTVDDAIRTAEALGLGEKGRYLLAASFGNVHGVYKPGNVVLRPELLKELNEGVAARFGKESPFDFVFHGGSGSSEEEIRTALENGVVKMNLDTDTQYAFTRPVAGHMFANYDGVLKVDGEVGNKKAYDPRTWGKLAEASMAARVVEATQHLRSAGNKIK
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: PFKA_MESHJ
Sequence: MSKKIGILTSGGDAPGMNSAISFLAKSALSLGFEPYLIFDGYSGIIARKILPAKNFPYNGISSFGGTAIGSSRFPEFKKEEVQNKAVEILSEIGISSLVVVGGDGTYNGGYKLHLKGIKVIALPGTIDNDIQFTDYTIGFDTALNTIVETIDKLRDTANSHRRCFVVEVMGRHCQDLALYSAMATGSEILITNTNILTPEEVSQKVLEQFAKGKPSVIVTITENILPNLKEFAAKIEELTKISTRSLEVGHTQRGGRPSAFDRILAAKMAMKAMELINQDKSGLAISYLDGKIQTFDIAKVVSKPVRKTNDLVLEINKINQN
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_METM5
Sequence: MKVVHTVGKRRTAIARATAKEGSGKIRINKKPLELMEPKYIKMKLMEPVILAGEALSDIDVDIDVKGGGIVSQMDATRTALGKAIVEFTGKMELKEKFLSYDRTLLVSDARRTEPHKPSKSSKGPRAKRQKSYR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HIS1_ACET2
Sequence: MRYLTIALSKGRLTDMSVELFEAIGIDCTELKNSSRKLILTDEKNKIKFFLAKPSDVPTYVEYGAADIGIVGKDTLMEEGRHLYEVLNLGFAACKMVVAGPAELMGKLDRLTNKRVATKYPRIAREYFEHKRKESIEVIKLNGSVELAPLVGLSEVIVDLVESGRTLKENGLVVLDTIADISARLVVNRVSMKMKSERINPIIDAIRKELEKR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRBL2_RAT
Sequence: MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIRALLTGEEQNKSQQNSSRHPKAGKTDANTNSLVGN
What is the function of this protein?
Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation.  May also play a regulatory role in the cell cycle (By similarity).
What are the official names of this protein?
cAMP-responsive element-binding protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIC_BURM7
Sequence: MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLSGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: IGF1_RABIT
Sequence: MITPTVKMRILSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKAARSVRAQRHTDMPKTQKYQPPSTNKKMKSQRRRKGSTFEEHK
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts.  Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  May play a role in synapse maturation.  Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.  Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor I, IGF-I, Somatomedin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YOCE_SCHPO
Sequence: MNSNSTLFVRNLAFQTKQDDLTNFFSDVGPIKHAVVVTNPETGENRGYGFVTFSMLEDAQRAAKELKNKKLHGRILRLDFATPRKRSEVDTDQNKAVKKTIRQDNRPRLIIRNLPWSIKKPQHLEPHFSKFGKVREIKIPTKGGGRMCGFAFVWMKDRKAAEEAMNSLNGTEIDGRPIAVDWAVSKDAFEATTLKDASSEEENKEFVSDEGHSIVTEDASADSESEEEVDGHSEGKELAGESEEEGSNVDDVEDSGDSSSDKNSINHEIRDNEGLEDTVFVRNLLFECTEQELYNHFRQFGPLAYAKLVKDPATDRSLGRGFIKFRYEKDCQNCLEMASQLPTQEPTEAEKRFLPSVLVDEGIDTDSVSSRFLLHGRLLKVTSAVTRKEASDINQKSLQERKQKMGKGVDRRHLFLLNEGKIAADHPLFNSLSETDKTLRSQSIAQRKKLLEKNPTLHLSLNRLSIRNISRHIDPKILAMLGRQAIRGFMDDVSKGLRANITEEEENLDKGHRLKRGKSGGVLKQAKVETEKAGAGRSKGFGFMQFISHKYALMALRWLNGREITVKKIIDAEIEWARKHKIPEPQLPNIDYNDRPRRLIVEFAIENIQVVKRRQEKEKSFRQKAKQLKQQEDEDNLKRKRSESDVEDNEAKEKQAKVARIIQRKRMKRRSRKN
What are the official names of this protein?
Uncharacterized RNA-binding protein C4F6.14.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HAT1_ASPOR
Sequence: MASEGDWTCDANDAVQITLVQPGEQKPKTLSSFHPQFTYPIFGDDETIFGYKGLIIRLRFAAHDLRPHIHISYDEKFKTVGDTSAVDLIKTLSPFIPEEAFSTLPDYENAVQEDKDAKDFVPPGKLVHNYVTRGRTYEIWAASLADPQVRRLLDRAQVFVSLFIEAGTPLETEDPEWTLERWTVYFVYEKVKPPTPTASQYSIVGYATTYRWWFYQRDSPEKGTVTNDPFPGPEIRPAQLPARLRIAQFLILPPHQGSGHGTHLYTTIHTACFNDSTIVELTVEDPNEAFDALRDTADFHILRPEFLKHNVNINPDPYAELSKKQRPRRVPTSALIPTKLLHDIRSTYKIASTQFAHVLEMFLLGEIPTKNRHAGGANMSRLLVKKYNATDPNERRYYWWRMLVKQRLFKRSRDILIQLEMSDRIEKLEETVTNVEEGYEALIKVFTAREEALMAKQEESGESPETAVLEDSVASSSDSSTRDQRTKRKFTVEDEDEEEEGESEVSKRPKV
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NFUA_SALPB
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: HEM3_PSEP1
Sequence: MSTREIRIATRKSALALWQAEYVKARLEQAHTGLQVTLVPMVSRGDKLLDAPLAKIGGKGLFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLETLPAGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFEDRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHVDTADRVIAERALNKRLNGGCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRAAAEALGVQVAEDLLGQGAEAILKEVYGEAGHP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ZAPB_SALAR
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLAQEVQSAQHQREELERENNSLKEQQSGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: FMT_CAMC5
Sequence: MNIIFMGTPAYARTILDALVRAGIGVAGVFTQPDKPVGRKQILTPSEVKIYAQQNLPHAKIFQPKTLKEGTVAAEILALKPDFIVVAAYGKILPKSVLDIAPCINLHASILPKYRGASPIQAALLNGEKNTGVTAMLMDEGLDTGDMLGFTHVSCEGKRSAEMFEILGELAGELAVKTLFDFKNLTPQKQDDALATHCKKIQKSDGLVNLSEDAEQIYNKFRAFHEWPGVFLESGLKFLELNLAEGSGAAGEILRIEKDGFVVACGTGALKILALQEAGKKALDAKAYINGKRLVAGNKIS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.