PharMolix/UniProtQA huggingface dataset:
Protein: HSLU_FRATF
Sequence: MTQIMTPKTIVHELERHIIGQNDAKKAVAIALRNRWRRMQLDNEMRQEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKDVESIIRDLVETAVKMKREEAKEKVTEKAARLAEDRILDVLIPPARTSESKVGFANEPAEDAASKKEKENKTREIFRKKIQNGELDDKEIEIEVAVAPKTIGVMGPPGMEDMTSQLQDLFSSLSTDKKKNKKMRIKDAIKLAQDEEAAKLVNEEDIKARALEAVEQNGIVFLDEIDKVCRKSSNSGADVSREGVQRDLLPLVEGSTVSTKYGVIKTDHILFIASGAFHVAKPSDLIPELQGRLPIRVELKSLEIEDFVRILREPDCSILKQYIALMKTEGIDLSFEEDAIRKIAEIAYKVNEEVENIGARRLHTVMERLLEKISFDAPELVEKNINITTDYVNEKLGNLVKNKDLSQYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_CHLPM
Sequence: MLKVKIVRLNKQAFLPVYATAHAAGMDVSACLEEPVVVEPFSTALIPAGFAIELPIGYEMQLRPRSGLALRSMITLANSPATIDADYRGEVKVILINHGPQPFTVNNGDRIAQMVVARVEEVSFEEVSELGETVRGDGGFGHTGTVRS
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: F16PA_NEIMA
Sequence: MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMAGTGNIQGEDQKKLDVIANNIMIDTLKANPAVAGLASEEEDSFVSAGENGRYLVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAEIHRILMRGGVFMYPQDKRDPSKPGKLRLMYEANPMALILEQAGASASNARQDILGIRPESLHQRVAVIMGSSEEVDYLNRLHSK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_LAWIP
Sequence: MFSFFIRKIFGSKNDRYLKSLSPILDQINALESTMKALSDKEIPVQLATFKQQLQEGKRTIDELLPEVFALVRETSFRVLGMRHFDVQLIGGISLHRGKIAEMKTGEGKTLMATLPVVLNALEGKGVHVVTVNDYLAQRDAEWMGALYSALGLTTGVLTSGLSDDARKEAYAADITYGTNNEFGFDFLRDNMKFYPNQLVQRGHFFAIIDEVDSILIDEARTPLIISGGSEQSTTMYTQIDKIIRNLKPQQDFSIDEKGKVVILSDEGAVQVEKALGIDNMYDPSNIAIQHHVLQALKAHYIFRRDVDYIVKDDQVVIVDEFTGRLMPGRRFSDGLHQALEAKEMVTVAAENQTLASITFQNYFRMYNKLAGMTGTADTEAVEFAQIYGLEVVVIPSNKPMIRKDHSDVIYRTRKEKFDAIVKAIIELHKKGQPVLVGTISIETSELISSMLRKKNISHNVLNAKHHAQEAEIIAQAGQVGKVTIATNMAGRGTDIVLGDSVVELGGLHILGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDDLMRLFGSDKLSGLMQRLGMEEGEPIENIMVSRAIESAQKRVEGHHFEIRKSLLDYDNVMNQQRTVIYTLRHNIMNDPEPMDIILEYLDELLSDIYIELEDNDNNELNKSIHTQLYDIMNLSQVMSIDNTLPTKEQAKTLILSMFEKLKSKAGEAYNDLLRYVLLEELDRCWKDHLRNMDFLREGIGLRGYGQRDPKLEYKKEGFVLFQELLANIREGVFRTFTRLHLEKKEDNFFQHEPINDLWYPASHEKETKFQVKKTDRVGRNDLCPCGSGKKYKKCCGVH
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RNAM_PLEOS
Sequence: VRPYLVAFYESH
What is the function of this protein?
Has ribonuclease activity towards yeast tRNA, polyadenine, polycytosine and polyguanine, but lacks ribonuclease activity against polyuracil.  Has antiproliferative activity towards L1210 tumor cell line with an IC(50) of 41 uM.  Lacks mitogenic activity towards murine splenocytes and does not inhibit HIV-1 reverse transcriptase.
What are the official names of this protein?
Ribonuclease.
Protein: TRMB_TRIV2
Sequence: MSALPFVRVRQHVNPLAQKYLTPANPLEWEKVYSSPHQPLHLDIGCARGRFVLQMAQVEPRWNFLGLEIREPLVIEANQFRSQLGLSNLHYLYCNANNSLQPLLSSLPTGILQRVTIQFPDPWFKTRHAKRRVVQPELVQDIANYLAVGGVVFLQSDMEFVAVEMCDRFAANPAFKKVGSGEWLSENPLPVATERETTTQNRGEPVYRALFERIS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RUVA_FINM2
Sequence: MYSYIIGVITEVHENYIVLENNNIGYKIFITDFFRDNVSAFDEYKVYTEFVEREDASILYGFSSQKERELFNLLTDVTSIGPKYAMNILSTMTVDECKTAIITDDIKLLTQAPGVGKKTASRIILELKEKIEKDFVPSEKPVNKEVKRSNDSEFAREALLQLGYFKNDVDAFIENTDISGLSIEDIMKKAMKSLDSSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: IXPDE_UNKP
Sequence: MTTYDTQPSTLIRNAAAIMTGGRGTADDPSRVPGPDIRIVGDTIDAIGALAPRPGETIVDATDCVIYPAWVNTHHHLFQSLLKGEPAGLDATLTPWLAATPYRFRALFDERRFRLAARIGLIELARSGCATVADHNYVYYPGMPFDSSAILFEEAEKLGLRFVLLRGGATQTRQLEADLPTALRPETLDAYVADIERLAARYHDASPRAMRRVVMAPTTVLYSISPREMRETAAVARRLGLRMHSHLSETVGYQDSAYSMYGKSPVAFCGEHDWLGSDVWYAHLVKVDADEIALLAQTGTGVAHCPQSNGRLGSGICPVREMADAGVPVSIGVDGAASNEAADMISEVHMTWLAQRARLGMLAQPAYRGGSFEGGAGAASIAEVIHWGTAGGARVMGLDEVGKVAVGYAADIAVYRLDDPRYFGLHDPAIGPVASGGRPSVMALFSAGKRVVVDDLIEGVDIKELGGEARRVVRELLREVVV
What are the official names of this protein?
Isoxanthopterin deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
Protein: PPE40_MYCTU
Sequence: MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASAAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGSGNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNTGFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR
What are the official names of this protein?
Uncharacterized PPE family protein PPE40.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: METE_PHOPR
Sequence: MTITTENKTVTHILGYPRVGSQRELKFAQEKYWRGEIEQNELKEVGSLLRHRHWGDQVGAGLDYVSVGDFAWYDHVLNTSMLLGHIPKRHDNGFPDLDTLFRIARGKAPTGCSCAASDMTKWFNTNYHYIVPEFTEDDQFNVSWQQLFGEVAEAKKAGHKVKPVLLGPVSYLWLGKEKEEGFDRLSLLPRLLAAYQKILSKLEALGVEWVQIDEPVLALELPKPWAESFKLAYQVLNGNTKLLLTTYFDNITHHLDKIVELNIDGLHVDLSAAPEQLNAVVDALPENWVLSAGVVNGRNVWRADLSHVLDVLQPVKAKLGQRLWVGSSCSLLHSPIDLDLETDLSPEVRQWLSFAKQKCREFLVAQALDGNAIAIQECAKYSAPIKARATSALVNNPDVRQRTNAITAALAERTAPYAERTRQQRAALNLPLLPTTTIGSFPQTNEIRTQRRDFKAGYLTEADYNTALKGHIADAIQRQEDLDLDVFVHGEAERNDMVEYFAELLEGFAVTRFGWVQSYGSRCVKPAVIVSDIYRAKPMTVEWTTYAQSLTDKLVKGMLTGPVTILGWTFPREDLPRQGIANQIALALRDEVSDLQAAGIKIIQIDEPAIREGLPLKESQWQAYLDWAVNAFKISAASAEPQTQIHTHMCYSEFNHIIKSVAALDADVITIETSRSDMELLKAFEEFDYPNEIGPGVYDIHSPNIPSIEQIVHLVEKAETLIPIERLWINPDCGLKTRNWEETEAALRSMVEATKKLREQWQEKAV
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RUVA_MAGMM
Sequence: MIAQLKGSLAAKHPDHVVMDVHGVGYRVFISLATYNELPTVGEACLLYTVTHVREDAFLLYGFHSESQRKVFNLLTSVNGIGTKLALAALSSHTPEALLTALSREDLTLLCTIPGVGKKTAQRMAMELKDKLGALPMAAPTTAIGAATMAANPAGLREEVASALLNLGYKPPQVDAALAKLFSAGEITDISVALKGALKLLAPA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ARNA_SALPB
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYDIAAIFTHADNPAENTFFGSVSRLAAGLGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSVDVAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: RL9_NOCFA
Sequence: MKLILTADVDNLGAPGDTVEVKDGYGRNYLLPRGLAIVASRGAQKQVEGIRRAQEARRVRDLDHANELKQAIEGLSAVSLSVKTAGTGKLFGSVTQSDVAAAIKAAGGPVIDKRSIELPKSHIKSTGKHTIAVHLHPDVTAKFDLQVDAAAS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ZDH23_ARATH
Sequence: MYVVTPPQRSGFGSDCDLRVYQTWKGSNIFCLQGRFIFGPDVRSLGLTISLIVAPVTIFCIFVASKLMDDFSDSWGVSIILVAVVFTIYDLILLMLTSGRDPGIIPRNSHPPEPEVVDGNTGSGTSQTPRLPRVKEVEVNGKVFKVKYCDTCMLYRPPRCSHCSICNNCVERFDHHCPWVGQCIAQRNYRFFFMFVFSTTLLCVYVFAFCCVYIKKIKESEDISILKAMLKTPASIALILYTFISTFFVGGLTCFHLYLISTNQTTYENFRYSYDRHSNPHNKGVVDNFKEIFFSPIPPSKNNFRAMVPRENPMPSRSVVGGFMSPNMGKANDDIEMGRKGVWAMAEHGDGKDGNNNERFHVNDNELNELSPDMGNIVNGDEQINRPNNHPRNANWEMSPEVMALSARRA
What is the function of this protein?
Palmitoyl acyltransferase.
What are the official names of this protein?
Probable protein S-acyltransferase 6, Probable palmitoyltransferase At5g41060, Zinc finger DHHC domain-containing protein At5g41060.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SLX1_TALSN
Sequence: MTTTVSEEAVLTKPIPAFYCCYLLRSAKRPSALYIGSTPDPARRLEQHNGFAKGGAKRTERNTLRPWEMVAIVEGFPSRTGALQFEWSWQHVHTTRHIGAVETDQLNRKRKNPPTDKGSGIWTSTPKVLGNLHQLLRSTYFGTWPLTVRFLSSEAHNHWQRWIERADGLLPDTIRVKLDFRAEGASVLDSNLPANDMTHIDATYGGIQEHLAKSTSLLGDNTNSLSCEVCQQQLSTQTEIIVVCSHRRCHAVFHVNCISQLFLEDEGSSGLVPILGECPACRQEVTWVELMKELSMRLHGGKNATKLLKGERKDKANTQGTKSSKGGKKPAKTGDYTLDGDYEDLDEDWMNAVNVEPSSEDGDRNAANVKGSTGRVEIVIDDSEEDGFD
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB_THEFY
Sequence: MSEHDRELVSPEAALDDHAVESALRPRTLDEFVGQDRVREQLSLVLRSAQQRGTAPDHILMSGGPGLGKTTLAMIIAAELGAPLRITSGPAIERSGDLAAVLSTLREGEVLFLDEIHRMARPAEEMLYVAMEDFRVDVMVGKGPGATAIPLEIAPFTLVGATTRAGMLPAPLRDRFGFVAHMDFYSPEELELILHRSARLLGIELLDDAAAEIARRSRGTPRIANRLLRRVRDYAQVRGDGRLTLECARAALSLYEVDDEGLDRLDRAVLDALLRRFRGGPVGLSTLAVSVGEEPETVEIVAEPFLVRAGFIARTPRGRVATPQAWAHMGLTPPPDAAFGAAALFDPDEEP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: C71AE_ARATH
Sequence: MEMIIISLCLATILALLLLKQFLNRTYTAKVNLPPSPWRVPVIGNLHQLSLHPHRSLRSLSHRYGPLMLLHFGRVPVLVVSSSDVAHDLMKTHDLKVANRPQLKVVEKIFNGGREMVFSPYGEYWRQIKSVCIVNLLNKKKVQSFEKVREEEISEMMERVEKASSDSSPLNLSELLLTLTSDVTSRVSLGRKYSKEESMSDFKIQMRKITELVGGFPVGEYIPCLAWIDKLRGVDEKAEEVSKAFGDLMEKVLQEHLDATDKPTLDFVDVLLSLERHERNGVQIRRSDIKFLILDMFLAGTETTYALLEWIMTELIRHPECMKKLQDEIRAKATKLILYISEEDVEDMKYLKAVVKEVLRLHPPLPLLVPRELSEDIKLKGYDIAAGTQVIINAWAIQRDTMTWGIDAEEFRPERHLDSLVDFRGTNFEFIPFGSGRRICPGIGFAMALVEVTLANLVNRFNWRMEVQHSGDEYDLAESTGLDVCRKFPLIVFPSPA
What are the official names of this protein?
Cytochrome P450 71A14.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1749_CLOPE
Sequence: MSIKLINIGFGNIVSANRLVAIVSPESAPIKRIIQEARDRGMLIDATYGRRTRAVIITDSDHVILSAVQPETVAHRLSTKEEVVVEDDE
What are the official names of this protein?
Putative regulatory protein CPE1749.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: LOLA_ALIF1
Sequence: MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDGNTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDNYSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVVEQDGQRSDFDFTKFEAKKPAKDNFTFAIPDGVDIDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TOLL6_DROME
Sequence: MIYYMLLILPVVLAQDQQHTTESLSTKHHQQQQLSHSNAIMGEAGVSNSQLMQPSTPARTLRPLTAGAGGDPSLYDAPDDCHFMPAAGLDQPEIALTCNLRTVNSEFDTTNFSVIPAEHTIALHILCNDEIMAKSRLEAQSFAHLVRLQQLSIQYCKLGRLGRQVLDGLEQLRNLTLRTHNILWPALNFEIEADAFSVTRRLERLDLSSNNIWSLPDNIFCTLSELSALNMSENRLQDVNELGFRDRSKEPTNGSTESTSTTESAKKSSSSSTSCSLDLEYLDVSHNDFVVLPANGFGTLRRLRVLSVNNNGISMIADKALSGLKNLQILNLSSNKIVALPTELFAEQAKIIQEVYLQNNSISVLNPQLFSNLDQLQALDLSMNQITSTWIDKNTFVGLIRLVLLNLSHNKLTKLEPEIFSDLYTLQILNLRHNQLENIAADTFAPMNNLHTLLLSHNKLKYLDAYALNGLYVLSLLSLDNNALIGVHPDAFRNCSALQDLNLNGNQLKTVPLALRNMRHLRTVDLGENMITVMEDSAFKGLGNLYGLRLIGNYLENITMHTFRDLPNLQILNLARNRIAVVEPGAFEMTSSIQAVRLDGNELNDINGLFSNMPSLLWLNISDNRLESFDYGHVPSTLQWLDLHKNRLSSLSNRFGLDSELKLQTLDVSFNQLQRIGPSSIPNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYANQITTLDIKSLRILPVWEHRALPEFYIGGNPFTCDCNIDWLQKINHITSRQYPRIMDLETIYCKLLNNRERAYIPLIEAEPKHFLCTYKTHCFAVCHCCEFDACDCEMTCPTNCTCFHDQTWSTNIVECSGAAYSEMPRRVPMDTSELYIDGNNFVELAGHSFLGRKNLAVLYANNSNVAHIYNTTFSGLKRLLILHLEDNHIISLEGNEFHNLENLRELYLQSNKIASIANGSFQMLRKLEVLRLDGNRLMHFEVWQLSANPYLVEISLADNQWSCECGYLARFRNYLGQSSEKIIDASRVSCIYNNATSVLREKNGTKCTLRDGVAHYMHTNEIEGLLPLLLVATCAFVAFFGLIFGLFCYRHELKIWAHSTNCLMNFCYKSPRFVDQLDKERPNDAYFAYSLQDEHFVNQILAQTLENDIGYRLCLHYRDVNINAYITDALIEAAESAKQFVLVLSKNFLYNEWSRFEYKSALHELVKRRKRVVFILYGDLPQRDIDMDMRHYLRTSTCIEWDDKKFWQKLRLALPLPNGRGNNNKRVVSGCLSGRTPSVNMYATSHEYQAGNGGVIPPPSARYADCGSNNYATINECAAAGGGRGYKPIPTSASAAAAACKFNTMNQLSKKQQRDLSVAGMAKTLEHQHHHNHQANRRSQHEYAVPSYLPSAAPAYDSVDYAKQQIRNNANCECVNLGTAKRAAGKNPASGLPSSFSSNFVPPGGASYNCKKSCSCIGDDELLCSCGGGGGIGVNLLESGTQSSVTMSSSSNNSRQPELTHYESNLSLNDDEDEDHDQQKNLWA
What is the function of this protein?
Toll-related receptor which binds to the neurotrophin spz5 (PubMed:10973475, PubMed:23892553).  Functions in olfactory circuit assembly by promoting synaptic partner matching between olfactory receptor neurons (ORN) axons and projection neurons (PN) dendrites partners in the antennal lobe (PubMed:25741726).  Involved in the targeting of specific classes of PN dendrites (Va1d, Va1v, DC3 and DA1) (PubMed:25741726).  Functions with Toll-7 to regulate motor axon targeting and neuronal survival in the central nervous system (CNS) (PubMed:23892553).  Possibly functions with 18w and Toll-8 during convergent extension, to help direct proper planar cell polarity, cell intercalation and axis elongation (PubMed:25363762).  Promotes heterophilic cell adhesion with 18w in vitro (PubMed:25363762).  May be an upstream component of the NF-kappa-B (rel) regulatory cascade (PubMed:23892553).
What are the official names of this protein?
Toll-like receptor 6.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PPIL2_MOUSE
Sequence: MGKRQHQKDKMYITCAEYTHFYGGRKPDISQTSFRRLPFDHCSLSLQPFVYPVCTPEGVVFDLLNIVPWLKKYGTNPSTGEKLDGKSLIKLNFAKNSEGQYHCPVLYSVFTDNTHIVAIRTTGNVYTYEAVEQLNIKAKNLRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFFHVKNNMRIIDPDEEKAKQDPSYYLKNTNSETRETLQELYKEFKGDEILAATMRPPEKKKVDQLNAAHYSTGKVSASFTSTAMVPETTHEAAVIDEDVLRYQFVKKKGYVRLHTNKGDLNLELHCDLTPKTCENFIKLCKKQYYDGTIFHRSIRNFVIQGGDPTGTGTGGESFWGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAYLDKKHTIFGRVVGGFDTLTAMENVESDPKTDRPKEEVLICTTTVFVDPYEEADAQIAQERKKTQHQVDPEAKVKMSQPQPGNQGPQTYRQGVGKYIHPAATKRSAEEEPSTSTATPTAKKRPSRGFGDFSSW
What is the function of this protein?
Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates.  By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation.  May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance.  Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
RING-type E3 ubiquitin-protein ligase PPIL2, CYC4, Probable inactive peptidyl-prolyl cis-trans isomerase-like 2, PPIase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL9_BURM9
Sequence: MQIILLEKVANLGNLGDIVKVKDGYARNFLIPNRKARRATKDAIAEFEVRRAELEKVAAEKLAAAQAVGEKLNGQTFEITQKSGVDGRLFGSVTNGDVAELLKKAGYEIEKAQVRMPEGPLKMIGEHGVQVALHTDVVVDVTVNVIGDHA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NIKR_SHIFL
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel (By similarity).
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: HTPX_SHEFN
Sequence: MKRIFLLIATNFAILLVASIVMSILGVNTSTMGGLLVFAAIFGFGGSFISLAISKWMAKKTMGCEVITQPRDSMERWLVETVARQAEKSGIKMPEVAIYQSPEMNAFATGPSKNNALVAVSSGLLYGMTQDEIEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASMIVAYFSRIREFKADEGAARLAGKNKMIAALERLRQGPESGAMPAQMSAFGINGKRSIAELMMSHPPLEKRIAALKNS
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHS_RHOPS
Sequence: MVERLAAAERHKALQGVPGWREVDGREAIARIFTFKDFNEAFGFMTRAALVAEKNDHHPEWRNVYKTVEVVLTTHDAGGITRRDIDLASAMDAIARQFGVA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.