PharMolix/UniProtQA huggingface dataset:
Protein: PAF1_YEAST
Sequence: MSKKQEYIAPIKYQNSLPVPQLPPKLLVYPESPETNADSSQLINSLYIKTNVTNLIQQDEDLGMPVDLMKFPGLLNKLDSKLLYGFDNVKLDKDDRILLRDPRIDRLTKTDISKVTFLRRTEYVSNTIAAHDNTSLKRKRRLDDGDSDDENLDVNHIISRVEGTFNKTDKWQHPVKKGVKMVKKWDLLPDTASMDQVYFILKFMGSASLDTKEKKSLNTGIFRPVELEEDEWISMYATDHKDSAILENELEKGMDEMDDDSHEGKIYKFKRIRDYDMKQVAEKPMTELAIRLNDKDGIAYYKPLRSKIELRRRRVNDIIKPLVKEHDIDQLNVTLRNPSTKEANIRDKLRMKFDPINFATVDEEDDEDEEQPEDVKKESEGDSKTEGSEQEGENEKDEEIKQEKENEQDEENKQDENRAADTPETSDAVHTEQKPEEEKETLQEE
What is the function of this protein?
The PAF1 complex is a multifunctional complex.  Involved in transcription initiation via genetic interactions with TATA-binding proteins.  Involved in elongation.  It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II.  Also has a role in transcription-coupled histone modification.  Required for activation of the RAD6/UBC2-BRE1 ubiquitin ligase complex, which ubiquitinates histone H2B to form H2BK123ub1.  Also required for the methylation of histone H3 by the COMPASS complex to form H3K4me, by SET2 to form H3K36me, and by DOT1 to form H3K79me.  RNA polymerase II associated protein important for transcription of a subset of genes.  Required for both positive and negative regulation.  Negatively regulates MAK16 expression.  Also required for efficient CLN2 transcription in late G1 and may be involved in transcription of galactose-inducible genes.
What are the official names of this protein?
RNA polymerase II-associated protein 1, Protein PAF1.
What is the protein family that this protein belongs to?
Belongs to the PAF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: PPID_BUCAP
Sequence: MIKYLKSRLNIIIVKCILGIIILSLVFGTINNYFNRDTTRYIAKVNGEEISFITLQKMYIDERKKQEKILGQDFEKIKKNKKFKEETYNYILSQLINNILLEQYTKRMNFNIQDNEIKKIIFNIPIFQENNEFNKKKYLNYLSSKNLTHYEYVSLIRKKLNTTYLINAISETDFILDNEQKKIIKLLSEKRIIKKAIIKINPIINNQKVTEKEINNYFDQHKNEFYTPEKFKISYIQLKPNKFKIQCSNEEIKNWYKKNIDKYSNQERRQYSIIQTKTKNEALSILSELKKGEDFSKIAKEKSIDPFSSEQGGNIGWITKNFVPNEIKIANLEKIDQISNIIKFNNNFLIIKLNKILPKKYKKISEVSDLIENEIKYQKSLNTYKKLKDKIAIIAKKNINRFDLILKKTNILPKETNWFDKDSVPKELQNPILKKIIFKKGLLDRQKKLKSHSGLIVLNDHQSFLLSIKNFQKKRIKKLKDIKRNIVNKLKYIKAVEKTKNKLKKILFQLKIGNEHILKKENIIFEEYETVSRYDKNPNISVIFAMPHPKEEKNVYTMYQNKNKNFVIALLDKVYNEKFSNEEEKIIIKYLEKNNIDVTFQCFLQNLHRKATILYNKTDNF
What is the function of this protein?
Chaperone that functions as a gatekeeper on the periplasmic side of the SecYEG translocon.  Facilitates the translocation of precursor proteins across SecYEG by interacting with the translocating substrate.  Also plays a role in the release of newly synthesized secreted proteins at the periplasmic exit site of the Sec translocon.
What are the official names of this protein?
Periplasmic chaperone PpiD, Periplasmic folding chaperone.
What is the protein family that this protein belongs to?
Belongs to the PpiD chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Located at the lateral gate of SecY.
Protein: THIG_BACAC
Sequence: MLNIGPFSFHSRLLLGTGKFPDFDVQQKAIDVSEAEVLTFAVRRMDIFDAKQPNLLEKLDVKKYKLLPNTAGAKNAEEAVRIAKLAKASGLCDMIKVEVIGDDRTLLPDPVETLRASEMLLEEGFIVLPYTSDDVVLARKLQELGVHAIMPGASPIGSGLGIVNPLNLSFIIEQATVPVIVDAGIGSPADAAFAMELGADGVLLNTAVSGAKDPIKMAQAMKLSIEAGRLGFEAGRIARKRCATASSPLEGMSVVE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF1_CHLPN
Sequence: MLNIHDILGNDDENLLSYQCKHITKDKLTLPSHDFVDKVFGLSDRNNRVLRSLQTMFSHGRLANSGYLSILPVDQGIEHSAGASFAINPIYFDPENIVKLAIESGCSAVASTYGTLSLLSRKYAHKIPFMLKLNHNELLSYPTKYHQIFFTQVEAAYSMGAVAVGATVYFGSETSNEEIVAVSNAFAKARSLGLATVLWCYLRNPAFVANGVDYHTAADLTGQADHLGATLGADIVKQKLPTCQGGFKAINFGKTDERVYSELSSNHPIDLCRYQVLNSYCGKVGLINSGGPSGKNDFTEAARTAVINKRAGGMGLILGRKAFQRPLSEGIQLLNLVQDIYLDPNITIA
What are the official names of this protein?
Probable fructose-bisphosphate aldolase class 1, Probable fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PSEA6
Sequence: MGQKVHPTGIRLGISKPWTSTWYANTADYADNLFNDHQVRQYLTKALKTASLSKIVIERPAKSIRVTIHTARPGVVIGKKGEDVEKLRKHVSKLAGVPAQINIAEVRKPELDGQLVADSIASQLERRVMFRRAMKRAVQNAMRIGAKGIKVQVSGRLGGAEIARAEWYREGRVPLHTFRADIDYATSEANTTYGIIGVKVWIFKGEVLGGLPLTQEQPAQPKKKGRSPKREG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DDL_SYNE7
Sequence: MAAQKVGLLFGGRSGEHEVSIRSAAAIASALADPSNRDRYQVLPFYIDKEGGWHSGETAAQVLANQKPLFVEEPSDRWQFPADCRDVEVWFPILHGPNGEDGTIQGLLTLMQRPFVGSGVLGSALGMDKIAMKQAFAQASLPQVAYVAVNRSQVFSDPCRYTSLLEQIETELGYPCFVKPANLGSSVGIAKVRDRAELEAALDQAAALDRRLIIEAAIDNPREVECAVLGNDYPQASILGEITYDSDFYDYETKYTDGKAQLLIPAQLSAELQQKLQELAIAAFQAVDASGLSRLDFFLDSQGQIFINEINTLPGFTALSMYPQLWAASGVAFPDLVHRLIQLALER
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHF_RHOCB
Sequence: MPNSPQNPSRKALYTEEERARRDATPWTLVQAILAPLQFLAFGVSLVLVVRFLFTGEGYEAATISILIKTLLLYTIMVTGAIWEKVVFGQYLFAPAFFWEDVFSFGVIALHTAYLWALFTGQPDNMQMFIALAAYATYVINAGQFLWKLRQARLQAASEDAGTLVMERGTR
What are the official names of this protein?
2-vinyl bacteriochlorophyllide hydratase.
Protein: UREG_PROMP
Sequence: MSSKLRVGVAGPVGSGKTALVETLCIALKKRYKIAVVTNDIYTKEDANFLIKKKILEEGRIVGVETGGCPHTAIREDCSLNKNAVMDLENKYDPLDFIFVESGGDNLAASFSPELVDLSIYVIDVSAGDKIPRKGGPGITRSDLLLINKIDLADMVGANLNIMQNDTNMMRDGKPWFFTNLSSGSGVDNVIKYLVAQIPNI
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLA18_ARATH
Sequence: MDRCIYGCSVITIFFSFFFLLNASALESGHHNITGSGQINSNSVLVALLDSRYTELAELVEKALLLQTLEDAVGRHNITIFAPRNEALERDLDPDFKRFLLQPGNLKSLQTLLLSHIIPKRVGSNQWPEENSGRVKHVTLGHDQVLHLSKLKGTNGKRLVNSAVITRPDDLTRPDGLIHGIERLLIPRSVQEDFNRRRNLRSISAVLPEGAPEIDPRTNRLKKSATAVSVPAGSPPVLPIESAMAPGPSLAPAPAPGPGGAHKHFNGDAQVKDFIHTLLHYGGYNEMADILVNLTSLATEMGRLVSEGYVLTVLAPNDEAMGKLTTDQLSEPGAPEQIMYYHIIPEYQTEESMYNSVRRFGKVKYETLRFPHKVGAKEADGSVKFGSGDRSAYLFDPDIYTDGRISVQGIDGVLFPEEKEEETVKKPTGPVKKVVQPRRGKLLEVACSMLGAIGKDSYLSRC
What is the function of this protein?
May be a cell surface adhesion protein.
What are the official names of this protein?
Fasciclin-like arabinogalactan protein 18.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_ACIBC
Sequence: MENFEVIKALFLGFVEGLTEFLPISSTGHLILFGHIIDFHSDGGRVFEVVIQLGAILAVCWLYRQKIINLIKGFFSGDVESRHFAISVLIAFFPAVIIGVLAVDFIKSVLFSPIVVAIALIVGALIIFWVESKQFEHKTDDATKITFKQALLVGLAQCVAMIPGTSRSGATIVGGMFAGLSRKAATEFSFFLAMPTMLGAATFDLIKNADVLTSDNMVNIGVGFVAAFIAALLVVKALVLFVERHTLRVFAWYRIVLGVIILIAAMFFNLSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_LISMH
Sequence: MEIKDLQDYVAIVNDWPKKGIVFKDITPLMNDGEAYRFATDKIVEYAKELKIDIIVGPEARGFIIGCPVAYALGIGFAPVRKPGKLPRETIEMEYDLEYGTNKLSMHSDAIKPGQRVLITDDLLATGGTIEATIKLVEELGGIVAGCAFLIELKELEGHKKLNGYDRLILMQL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_BACSU
Sequence: MYAIIKTGGKQIKVEEGQTVYIEKLAAEAGETVTFEDVLFVGGDNVKVGNPTVEGATVTAKVEKQGRAKKITVFRYKPKKNVHKKQGHRQPYTKVTIEKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21, BL20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: APCB_AGLNE
Sequence: MQDAITSVINTADVQGKYLDDSSLNKLKGYFATGELRVRAAATIAANAANIIKESVAKALLYSDITRPGGNMYTTRRFAACIRDLDYYLRLATYGMLAGDPSILDERVLDGLKETYNSLGVPIGATIQAIQAMKEVTSGLLGVDAGQEMALYFDYICSGLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the core of the phycobilisome.
Protein: KC1A_CAEEL
Sequence: MAGVMSVKDFIVATKYKLIRKIGSGSFGDIYVSINVTNGEEVAIKLESNRARHPQLLYESKVYRILQGGVGIPHIRWYGTEREYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMIGRIEYVHVKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRTHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRGTLPWQGLKAATKKQKYEKISEKKMTTSVEHLCKGFPAEFPMYLSYTRGLRFDESPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAQQSQSSGVPGTNTTTQGATVPSAGVPAGVAPGGTTPQ
What are the official names of this protein?
Casein kinase I isoform alpha, CKI-alpha, CK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: NQO13_THET8
Sequence: MVVLAVLLPVVFGALLLLGLPRALGVLGAGLSFLLNLYLFLTHPGGVAHAFQAPLLPGAGVYWAFGLDGLSALFFLTIALTVFLGALVARVEGRFLGLALLMEGLLLGLFAARDLLVFYVFFEAALIPALLMLYLYGGEGRTRALYTFVLFTLVGSLPMLAAVLGARLLSGSPTFLLEDLLAHPLQEEAAFWVFLGFALAFAIKTPLFPLHAWLPPFHQENHPSGLADALGTLYKVGVFAFFRFAIPLAPEGFAQAQGLLLFLAALSALYGAWVAFAAKDFKTLLAYAGLSHMGVAALGVFSGTPEGAMGGLYLLAASGVYTGGLFLLAGRLYERTGTLEIGRYRGLAQSAPGLAALALILFLAMVGLPGLSGFPGEFLTLLGAYKASPWLAALAFLSVIASAAYALTAFQKTFWEEGGSGVKDLAGAEWGFALLSVLALLLMGVFPGYFARGLHPLAEAFAKLLGGGA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 13, NADH dehydrogenase I chain 13, NDH-1 subunit 13.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIR2_TOBAC
Sequence: MPLIPEEPLLASSPDRFCMFPIQYPQIWEMYKKALASFWTAEEVDLSSDTRHWETLTPGERHFITHVLAFFAASDGIVLENLAGRFMKEVQVAEARAFYGFQIAIENIHSEMYSLLLESYIKDSDEKSRLFRAVETNPCVEKKAKWALRWIDGSETFAERLVAFACVEGIFFSGSFCAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLLYSLLRTKLTEERVKGIVADAVEIEREFVCDALPCALVGMNGDLMSKYIEFVADRLLDALGYDKLYNAQNPFDWMELISLQGKTNFFEKRVGEYQKASVMSSLNGNGATHEFKLDEDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleoside-diphosphate reductase R2 subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGHF_ECOLI
Sequence: MARVVFRDARIYLIQWLTKIRHTLNQRQSLNTDKEHLRKIARGMFWLMLLIISAKMAHSLWRYISFSAEYTAVSQPVNKPSRVDAKTFDKNDVQLISQQNWFGKYQPVAAQVKQPEPVPVAETRLNVVLRGIAFGARPGAVIEEGGKQQVYLQGETLGSHNAVIEEINRDHVMLRYQGKIERLSLAEEERSTVAVTNKKAVSDEAKQAVAEPAVSVPVEIPAAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAAKPGADRSLFDASGFKEGDIAIALNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIALRYRLFCPPYWKKS
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
What are the official names of this protein?
Putative type II secretion system C-type protein YghF, Putative general secretion pathway C-type protein YghF.
What is the protein family that this protein belongs to?
Belongs to the GSP C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: OLFM4_MOUSE
Sequence: MSYSLLFLLALQFCLGSASRTTLTSAHSRELTTPPTSPQATAAWLPPGGTSWAEGGTVSQPLSNFTGSVDSHGTCQCSVSLPDTAFPADRVERLEYTAHILSQKFEREFSKVKEYVQLISVYEKRLLNLTVRVEVMEKDSISYTELDFELIKLEVKEMQKLVLQLKKNFVGSTHIIDMLEVEIRNMTLLVEKLESLDQNNVLSIRRQILALKTKLKECEASKSDLVPATPPPPAPGSCSHGGVVNISAPSVIQLNWLGFSYKYGAWGRDYSPQHPERTLYWVAPLNTDARALEYYRLYDSLDNLLIYSHFRDYRIRYGQGGGTVAFNNNLYVNWYNGGNIAKINLTTNVVDVNRPLPLAAYNNRFSYANVNWQDIDLAVDEQALWAIYATEASTGNIVISKLNDTTLEVISTWVTKQYKPSVSNAFMVCGVLYATRTLNTKTEEIFYYYDTNTEREGNLGITMRKMQERIQSINYHPFDQKLYVYNDGYLLNYDLVFLQTPRQPV
What is the function of this protein?
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase.  In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis.  May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation.  Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin (By similarity).
What are the official names of this protein?
Olfactomedin-4, OLM4.
What are the subcellular locations of this protein?
Secreted, extracellular space. Mitochondrion.
Protein: MRAY_NEIG2
Sequence: MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAVIAGLALFYLAANSANNILIVPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLAAFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVAIFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEK9_XENLA
Sequence: MSALGRYDRHCDSINSDFGDSVRSCGPEQEELHYIPIRVLGHGAYGEATLYRRTEDDSLVVWKEVGLARLSEKERRDALNEIVILSLLQHDNIIAYYNHFLDSNTLLIELEYCNGGNLFDKIVHQKAQLFQEETVLWYLFQIVSAVSCIHKAGILHRDIKTLNIFLTKANLIKLGDYGLAKQLSSEYSMAETCVGTLYYMSPEICQGVKYSFKSDIWAVGCVLYELLTLTRTFDATNPLNLCVKIVQGNWAVGLDNTVYTQELIEVVHACLEQDPEKRPTADEILERPILSWRRRDMEEKVSMLNRSNKKPRTGTVTEAPIAVVTSRSSEVYVWGGGKTTPQKLDVFKGGWRARQVCAGDAHFAVVTVEKELYTWVNMQGGSKLHGQLGHGDRASYRQPKHVEKLQGKSVQKVSCGSDFTVCITDEGQLYSFGSDYYGCLGVNQSAGSEVLEPLLVDFFLNEPVDQVSCGDSHIMALTRSKSVYSWGCGEYGRLGLDSEDDVYSPQKVEVQRGLCIVNVCCGSDGSFLLTLTGKVLACGLNEHNKLGLNQYTAGIINHEAFQEVPYTTSLTLAKQLSFYKIRSISPGRTHTAAIDERGRLLTFGSNKCGQLGVGDYRKHLGINLLGGPLGGKQVIRVSCGDEFTTAATADNHIFAWGNGGNGRLAMTPNERPQGSDICTSWPRPIFGSLHHVTDLSCRGWHTILIVEKVLNSKTIRSNSSGLSIGTLAQSCSSGGSGSREEDSDRESLTSDPSRGFRGTIEAEPETGPFNTTENMESSSCPSWLRQELEEAEFIPMPDTPNFVSAESSQNGTTSMQDVRETPPDALEKPSFQACTCSTLQEEVRKLQDLVSTYRHEQELLCRENSRLALEVQELNGKLQSAMQMNQVVNKHGEAIHQIQKQLSLHWKSSPPSSGNPEMSREDSDAESWCFLGTEACRSSSGTPM
What is the function of this protein?
Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation.  Important for G1/S transition and S phase progression.  Phosphorylates nek6 and nek7 and stimulates their activity.
What are the official names of this protein?
Serine/threonine-protein kinase Nek9, xNek9, Nercc1 kinase, Never in mitosis A-related kinase 9, NimA-related protein kinase 9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM4_ORYSJ
Sequence: MASRGGGGGGDGNSPPPSVSSPDVRPSSPLPATNSSPPQSGRRGGGRRRRGSASPYPSSPSLGGFETPPHPGRRTPSGGAAARQQRQNWTGGRFPPTPSTPMSTDDVPLSSEAGDEDTPETDGGGGGGAGADATPVFVWGTNISVQDVNAAILRFLRHFRDPRDAGRVDPVMDEGKYMRAIHRILELEGGESLDVNAHDVFDHDPDLYGKMVRYPLEVLAIFDIVLMDLVARIEPLFEKHIQTRIYNLKSSVCLRNLNPSDIEKMVSIKGMIIRCSSVIPELKEAVFRCLVCGFYSEPVMVDRGRVTEPHICQKEQCKATNSMTLVHNRCRFADKQIIKLQETPDEIPEGGTPHTVSVLMHDKLVDAGKPGDRVEITGIYRAMSIRVGPTQRTVKSIFKTYIDCLHIKKTDKSRLHVEDSMETDNPNANKTTEDDFLRDKVEKLKELSKLPDIYDRLTRSLAPNIWELDDVKRGLLCQLFGGNALRLPSGASFRGDINILLVGDPGTSKSQLLQYMHKLSPRGIYTSGRGSSAVGLTAYVTKDPETGETVLESGALVLSDKGVCCIDEFDKMSDNARSMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPTESRYNPRLSVIDNIHLPPTLLSRFDLIYLILDKADEQTDRRLAKHIVSLHFENPNIEELEVLDLPTLVAYISYARKHIQPQLSDEAAEELTRGYVEMRKRGNSPGSRKKVITATARQIESLIRLSEALARMRFSEMVEVQDVVEAFRLLEVAMQQSATDHATGTIDMDLIMTGISASERQRRDNLVAATRNLVMEKMQLGGPSVRMIELLEEIRKQSSMEVHLHDLRGALGTLMTEGAVVIHGDSVKRV
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM4, Minichromosome maintenance protein 4, OsMCM4.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: REX_STRPD
Sequence: MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIHAQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_ANADF
Sequence: MAKPYDPKDFYYRKAKKEGLRARSAFKIDEILRRHRLLRKGQAVLDLGAAPGGFLQILADEVGETGVAVGVDLEPVRRLGKPWVKTAIVDLLSPGALDQIRTLHAGPFQLVTSDMAPKTIGVKITDEARSLELVRMALDVAEKTLAPGGAFVAKVFMGGEFPVLKKELQARFDEVHVIRPEAVRESSYEVYVLGKGLRRAAARAAPTANATPTPTSTSTSTPTSTSTPTSTSTSTPAPTLTQTQTQTPKKPARRAPAKASTAGKAKAKTGASRRTR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHOC_SCHPO
Sequence: MERRKATVHVGNLAPSVTESLLYNAFIPFGEIISVALHRKEKAVDRSYAFVEFDEPEDAKEAMENMNYSILCDRCIRVSPANFALSAEETAVPDIAMLHPESADFQTFKSTSTPTS
What are the official names of this protein?
Uncharacterized RNA-binding protein C428.12c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LSM1_HUMAN
Sequence: MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLDEY
What is the function of this protein?
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165).  Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm1, Cancer-associated Sm-like, Small nuclear ribonuclear CaSm.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: RL31_DROME
Sequence: MTKTKGEKINKSAINEVVTRECTIHLAKRVHNIGFKKRAPRAIKEIRKFAEREMGTTDVRIDTRLNKHIWSKGIRSTPFRIRVRLARRRNDDEDSPNKLYTYVTYVPVSTFKNLQTENVESSDD
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: VATF_METM5
Sequence: MRIGVVGDPDVVVGFRLAGLTDVYEVKSPEQAAKAIEELNSNSEIGLIITTERIGEQVRDTISAVKKVVVEVPDKNGPIVRENDPVKVLVRNAVGVDIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RD50_PHYIT
Sequence: MRLSFILAVTCTGLLACATASDSEKAAKISNDQVLSGRQLIDTVAKDNKKRLLRAYKDAEDDSEDSKNVKPTADSKHADESEDSEDSQEERFSLIQTSNQPRYYWWFQHHMTPLDVRRDLELTADTINPIKRSVYTGYVDYYEDHCSYYENRKEEFCKAEDF
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PexRD50.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: PFKA_COXBU
Sequence: MTEIKKLIVLTSGGDAPGMNAAIRAVVRTALHYQFEVYGATAGFAGLVNGQVVPLNSRAVANCIQRGGTILKTGRFENFRFKAVRDKAREFLKKLQIDAMIVLGGNGSFAGASKLYQEGGPQMIGIPCTIDNDIQGTDYCIGFDTACNTALQAIDKIRDTAFSHERNFLIEVMGRSSGFIAVNVGIAGGAEIIALPEFHVDIDTLTQKIKKQHGKKSASIIVAAEANQPGHSFEVAKQIKEKTGIEYRVCVLGHTQRGGTPTVKDRVLASLMGAQAIEALKKGLTEKMIAYQNGKIAVAPLPDPDNGTRYFADEALLRVNNIICAM
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.