PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_RUEST
Sequence: MKTRDMNRDWIATAETLSSALPYLQRYDDAIVVIKLGGHAMGSDEGMESFARDVVLLRQVGVNPVIVHGGGPMINALLDKLQIKSEFVNGKRVTDAATMEVVEMVLSGMVNKRIVQAINAQGGKGIGLSGKDANLITCEATDPALGFVGTPSEVNADMLKNLFEKEFIPVIAPIGSGTAGETFNINGDTAAGAVAAALKADRLLLLTDVAGVKNAEGVVVTELKAADVEEMTAAGVIAGGMIPKTETALAAVRGGVRACTIVDGRVPNAVLLELFTDHGAGSMIRS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL1_ASPAC
Sequence: MKLSWLEAAALTAASVVSADELAFSPPFYPSPWANGQGEWAEAYQRAVAIVSQMTLDEKVNLTTGTGWELEKCVGQTGGVPRLNIGGMCLQDSPLGIRDSDYNSAFPAGVNVAATWDKNLAYLRGQAMGQEFSDKGIDVQLGPAAGPLGRSPDGGRNWEGFSPDPALTGVLFAETIKGIQDAGVVATAKHYILNEQEHFRQVAEAAGYGFNISDTISSNVDDKTIHEMYLWPFADAVRAGVGAIMCSYNQINNSYGCQNSYTLNKLLKAELGFQGFVMSDWGAHHSGVGSALAGLDMSMPGDITFDSATSFWGTNLTIAVLNGTVPQWRVDDMAVRIMAAYYKVGRDRLYQPPNFSSWTRDEYGFKYFYPQEGPYEKVNHFVNVQRNHSEVIRKLGADSTVLLKNNNALPLTGKERKVAILGEDAGSNSYGANGCSDRGCDNGTLAMAWGSGTAEFPYLVTPEQAIQAEVLKHKGSVYAITDNWALSQVETLAKQASVSLVFVNSDAGEGYISVDGNEGDRNNLTLWKNGDNLIKAAANNCNNTIVVIHSVGPVLVDEWYDHPNVTAILWAGLPGQESGNSLADVLYGRVNPGAKSPFTWGKTREAYGDYLVRELNNGNGAPQDDFSEGVFIDYRGFDKRNETPIYEFGHGLSYTTFNYSGLHIQVLNASSNAQVATETGAAPTFGQVGNASDYVYPEGLTRISKFIYPWLNSTDLKASSGDPYYGVDTAEHVPEGATDGSPQPVLPAGGGSGGNPRLYDELIRVSVTVKNTGRVAGDAVPQLYVSLGGPNEPKVVLRKFDRLTLKPSEETVWTTTLTRRDLSNWDVAAQDWVITSYPKKVHVGSSSRQLPLHAALPKVQ
What are the official names of this protein?
Beta-glucosidase 1, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: PSME1_RAT
Sequence: MATLRVHPEAQAKVDVFREDLCSKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEEKDEKKKGDEDDKGPPCGPVNCNEKIVVLLQRLKPEIKDVIEQLNLVTTWLQLQIPRIEDGNNFGVAVQAKVFELMTSLHTKLEGFQTQISKYFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
What are the official names of this protein?
Proteasome activator complex subunit 1, 11S regulator complex subunit alpha, REG-alpha, Activator of multicatalytic protease subunit 1, Proteasome activator 28 subunit alpha, PA28a, PA28alpha.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: NDHI_ENCCL
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPERKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YCIB_YERPP
Sequence: MKQLLDFLPLVVFFIFYKMYDIFVASGALIVATLVALAFTWLKYRKVEKMTLVTAAMVLVFGTLTLAFHSDLFIKWKVTVLYVLFALALLVSQWVMKKPLIQRMLGKELTLPDKVWSTLNLSWAIFFLVCGLLNIYVAFWLPQDIWVNFKVFGLTALTLIFTLISGVYIYRHMPEEQKKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADHA_MYCTO
Sequence: MVSPATTATMSAWQVRRPGPMDTGPLERVTTRVPRPAPSELLVAVHACGVCRTDLHVTEGDLPVHRERVIPGHEVVGEVIEVGSAVGAAAGGEFDRGDRVGIAWLRHTCGVCKYCRRGSENLCPQSRYTGWDADGGYAEFTTVPAAFAHHLPSGYSDSELAPLLCAGIIGYRSLLRTELPPGGRLGLYGFGGSAHITAQVALAQGAEIHVMTRGARARKLALQLGAASAQDAADRPPVPLDAAILFAPVGDLVLPALEALDRGGILAIAGIHLTDIPDLNYQQHLFQERQIRSVTSNTRADARAFFDFAAQHHIEVTTPEYPLGQADRALGDLSAGRIAGAAVLLI
What are the official names of this protein?
Probable alcohol dehydrogenase AdhA.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: THIG_LEGPA
Sequence: MWNLAGKELSSRLLLGTACYPSLEHMQQAILNSGTEVITISIKRQTSAGLDGESFWQAVKKLDCHFLPNTAGCRNAEAAINTAEIARELFDTHWIKLEVIGDDYNLQPEPFELIKATRILIDRGFEVFPYCTDDLVLCQKLVDAGCKILMPWGAPIGSGKGLINPYALETLRYRFPDITLIIDAGIGKPSHAVQAMEFGFDGVLLNTAVALANHPALMATAFRHAVIAGHQAFTGGMMSERNVAHPSTPLIDTPFWHQVNNL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMY3A_ORYSJ
Sequence: MGKQMAALCGFLLVALLWLTPDVAHAQTQILFQGFNWDSWKKQGGWYNMLKDQVGDIASAGVTHVWLPPPTHSVSPQGYMPGRLYDLNASKYGTKAELKSLIAAFHAKGIKCVADIVVNHRCADDKDGRGVYCIFKGGGPRGCLDWGPSMICCDDTQYSDGTGHRDTGADFAAAPDIDHLNPLVQRELSDWLRWLRRDVGFDGWRLDFAKGYSAAVARTYVQNARPSFVVAEIWNSLSYDGDGKPAANQDGQRQELVNWVKQVGGPATAFDFTTKGILQSAVQGELWRMRDKDGKAPGMIGWYPEKAVTFVDNHDTGSTQRMWPFPSDKVILGYAYILTHPGVPCIFYDHVFDWNLKQEINALAATRKRNGINAGSKLRVLAAESDMYVAMVDERVITKIGPRIDVGNIIPSDFHIVAHGNDYCVWEKSGLRVPEPEGRR
What is the function of this protein?
Important for breakdown of endosperm starch during germination.
What are the official names of this protein?
Alpha-amylase isozyme 3A, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SSUD_PARP8
Sequence: MNVFWFIPTHGDSRYLGTSQGARAADYDYFRQIAVAADTLGYEGVLLPTGRSCEDAWVVASSLIPATQRLKFLVAIRPGIASPGLSARMAATFDRLSGGRLLINVVTGGDAAELEGDGLFVDHDTRYEITDEFLRIWRGLLTSAHHGESVEFIGRHLKSKGGKLLYPPVQSPHPPLWFGGSSPAAHEMAGEHIDTYLTWGEPPEAVAEKIADIRARAAQHGRTIRFGIRLHVIVRETEDEAWAAADKLISKLDDDTVARAQEAFAKMDSEGQRRMAALHGGKRGSRKELEIYPNLWAGVGLVRGGAGTALVGNAEQVAARMREYAELGIETFILSGYPHLEESYRFAELVFPLLPGRQRANANGPLSGPFGEIVGNHYAPKASQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: DMPP_ACICP
Sequence: MSYQVTIEPIGTTIEVEEDQTILDAALRQGVWLPFACGHGTCGTCKVQVTDGFYDVGEASPFALMDIERDENKVLACCCKPQSDMVIEADVDEDPDFLGHLVQDYQATVIEIKDLSPTIKGIRLQLDRPIEFQAGQYINVQFPNIEGTRAFSIANSPSEVGIVELHIRKVEGGAATTYVHEQLATGDQLDISGPYGQFFVRKSDDQNAIFIAGGSGLSSPQSMILDLLESGDSRTIYLFQGARDLAELYNRELFEQLVKDYPNFRYIPALNAPKPEDQWTGFTGFVHEAVADYFENRCGGHKAYLCGPPIMIDSAISTLMQSRLFERDIHTERFLSAADGAAGQSRSALFKHI
What is the function of this protein?
Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme.
What are the official names of this protein?
Phenol hydroxylase P5 protein, Phenol 2-monooxygenase P5 component.
Protein: RTD1B_MACMU
Sequence: MRTFALLTAMLLLVALHAQAEARQARADEAAAQQQPGADDQGMAHSFTRPENAALPLSESARGLRCLCRRGVCQLL
What is the function of this protein?
RTD-1 and RTD-2 have similar antimicrobial activities against the Gram-positive bacteria S. aureus 502A and L. monocytogenes, the Gram-negative bacterium S. typhimurium, and the fungi C. albicans 16820 and C. neoformans 271A.  RTD-2 is 2-3-fold less active than RTD-1 against E. coli ML35.
What are the official names of this protein?
Rhesus theta defensin-1/2 subunit B, RTD-1 subunit B, RTD-1b, Demidefensin-1, RTD-2.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family. Theta subfamily.
Protein: DXR_PSESM
Sequence: MSGPQHITILGATGSIGLSTLDVVARHPTLYQVFALTGFSRLDELLALCIKHTPQYAVVPEQVAARKLQDDLAAAGLDTRVLVGEGGLCEVAAHPMVDAVMAAIVGAAGLRPTLAAVEAGKKVLLANKEALVMSGALFMQAVRQSGAVLLPIDSEHNAIFQCLPGDFARGLGAVGVRRIMLTASGGPFRETPLEQLQDVTPEQACAHPVWSMGRKISVDSATMMNKGLELIEACWLFDARPDQVEVVIHPQSVIHSLVDYVDGSVLAQLGNPDMRTPIANALAWPARVDSGVAPLDLFRIGQLDFQEPDEERFPCLRLARQAAEAGGSAPAMLNAANEVAVAAFLDGRIRYLEIAGIIEEVLNREPVTAVVGLDAVFAADAKARLLAGQWLERNER
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GRCR1_MOUSE
Sequence: MLRRETKPESDRPRKVRFRIASSHSGRVLKEVYEDGQAPGSLDSECASICAIDGLSDSEGQQNGHIGSEDNEQEKDQDNLLVLARTASEKAFGTRRVNILSKNGTVRGVKYKVSAGQALFNNLTKVLQQPSADLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEKNIALNGDYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDLLTKIERVQHPHECPSCGGFGFLPCSVCHGSKMSVFRNCFTDAFKALKCTACNENGLQRCKNCTC
What is the function of this protein?
May play a role in actin filament architecture in developing stereocilia of sensory cells.
What are the official names of this protein?
Glutaredoxin domain-containing cysteine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the GRXCR1 family.
What are the subcellular locations of this protein?
Cell projection, stereocilium. Cell projection, microvillus. Cell projection, kinocilium. Note=In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia.
Protein: T132C_MOUSE
Sequence: MRSEGAAPRRAARYGALSLVLATLLGQVTESRGVMDNIQRFSSLPPYLPVSFHVLRAETAFFLKEANPDPLRNASLQSRVESFFIYKAQQPPVLNVSYGPYSAEKVIPLDLMLNPNFLGPTSKFPFDWRLKAYILQEKVYLSHPKVQVLFHIVGRDWDDHRDEKLPCLRVFAFRDSREVRGSCRLGGPLGLCVAQLEMLPGWFSPPAVVSGRRRPAERPEGSPVELYYAVQPGDERGDCTGGDTRKDNAIRPGKDGQEGRTSHLQKIGTISLYRAQDSNQLSELRLDGNVVIWLPSQPVKQGDIVTASVTIANNSTVDHFILRAKVKKGVNILTVQTSEPRQWDVRQEVGNGGKHTTTSVACQRLGPGARNRSSNLFSEVMQMNFEIASFSSLSGTQPITWQVEYPRKGATDIAVSEIFISQKDLVAIVPLAMDTELLNTAILTGKTVAMPVRVVSVEENSTLRDISELVECKATDENVIKVSDHCDYVFVNGKEIKGKMDSVVNFTYQHLSAPLHVTVWVPRLPLQIEVSDTELSQVKGWRVPIVASKRPTRDSEEEEEEEQKGRGCTLQFQHATVRVLTQFVSEGAGPWGQLSHLLSPDWQFDITHLVADFMKLESPHIATLQDSRVLVGREVGMTTIQVLSPLSDSILAEKTVTVLDDKVSVTDLAVQVVAGLSVTLHPISENNKATSAVAMAEELLRAPKKEAIISTWLQFSDGSVTPLDIYDSKDFSLTAISLDEAVVSIPQPLSPWWPTVVAEGEGQGPLLRVDMSIAEACQKSKRKSVLAVGIGHVGVKFGWDDADSSQTGEKDEEEIKNHASDRRQKIQDLERPGQDELYHGNFPGDREEGALSATTTTKSLLDNNVGKSGRRDGARLHSIPIDFTNFPAHVDLPKAKTRGTLEENGLMQTAHGLSDLEIGMYALLGVFCLAILVFLINCATFAFKYRHKQVPLEGQASMTHSHDWVWLGNEAELLENIGDLSPPQDEHTTIIDRGLGGCEENNHLLLNGGSQKPTQSQVHRPPGSGGRQTREPRQEPANSPTSKMKKVKFATFTIPPEESCPTVNSILSGEDDIKWVCQDLDVGAPKELRTYLEKFQDSV
What are the official names of this protein?
Transmembrane protein 132C.
What is the protein family that this protein belongs to?
Belongs to the TMEM132 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HV43D_HUMAN
Sequence: MEFGLSWVFLVAILKGVQCEVQLVESGGVVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISWDGGSTYYADSVKGRFTISRDNSKNSLYLQMNSLRAEDTALYYCAKD
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-43D.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: TOLB_BRUA2
Sequence: MKIGIINTKIRTVFSAFACMIAASLVCTMPARAVVEININKGVIEPLPIAITDFLSADQLGSNITSVIAADLERSGLFAPIDKGAFIEKISNPDAAPRFEDWKVINAQALVTGRITKQPDGRLKAEFRLWDTFGGQQMIGQQFFTTPDNWRRVAHIIADAIYERLTGDKGYFDTRVVFVDESGPAQKRVKRLAIMDQDGANVRFISDGRALSLTPRFSPNRQEVTYMSFEGGSPKVYLLQLETGQRELVGNFPGMTIAPRFSPDGQKVVMSLLQDDGSANIYTMDLRNRTTTRLTSSQAIDTGASYSPDGSQIVFTSDRGGRPQLYVMGADGSNPRRISMGDGSYSTPVWSPRGDLIAFTKQSQGQFSIGVMKTDGSGERLLTSGFHNEGPTWAPNGRVLMFFRKAAGAGGPKLFTIDLTGRNERQIQTPNFASDPAWSPLLE
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HLDD_ALKEH
Sequence: MIIVTGGAGFIGSNLVHELNRRGRTDVIVVDNLTRGEKALNLADCVIADYYDKDDFITLIEADEGLGPVEAVFHLGACSATTEWDGRYMMRNNFEYSRALFHWCQDRRIPFIYASSAAVYGGNSVFTEHPEHERPLNVYGYSKLAFDQYLRRYLDDLSAQVVGLRYFNVYGPREQHKGGMASVVHHFSRQLRESGQVRLFEGSDGYADGEQRRDFVDVSDCVRLKLWLLDHPEVSGIYNCGTGRARTFNAMAHAVIDWFGHGEIEYIPFPEHLKGRYQSYTQADLSQLRAAGCDLAFNDIETGVRNYLDAVADAPAVMPS
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: ZHX3_HUMAN
Sequence: MASKRKSTTPCMIPVKTVVLQDASMEAQPAETLPEGPQQDLPPEASAASSEAAQNPSSTDGSTLANGHRSTLDGYLYSCKYCDFRSHDMTQFVGHMNSEHTDFNKDPTFVCSGCSFLAKTPEGLSLHNATCHSGEASFVWNVAKPDNHVVVEQSIPESTSTPDLAGEPSAEGADGQAEIIITKTPIMKIMKGKAEAKKIHTLKENVPSQPVGEALPKLSTGEMEVREGDHSFINGAVPVSQASASSAKNPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHVHQPLPTAKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASAGNVQHLIQAALPGHVVGQPEGTGGGLLVTQPLMANGLQATSSPLPLTVTSVPKQPGVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDASIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRAMIPGDHSSIIIDSVPEVSFSPSSKVPEVTCIPTTATLATHPSAKRQSWHQTPDFTPTKYKERAPEQLRALESSFAQNPLPLDEELDRLRSETKMTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDEGGEEDLASELRVSGENGSLEMPSSHILAERKVSPIKINLKNLRVTEANGRNEIPGLGACDPEDDESNKLAEQLPGKVSCKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLYEEDLQNLCDKTQMSSQQVKQWFAEKMGEETRAVADTGSEDQGPGTGELTAVHKGMGDTYSEVSENSESWEPRVPEASSEPFDTSSPQAGRQLETD
What is the function of this protein?
Acts as a transcriptional repressor.  Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation.  Is a regulator of podocyte gene expression during primary glomerula disease.  Binds to promoter DNA.
What are the official names of this protein?
Zinc fingers and homeoboxes protein 3, Triple homeobox protein 1, Zinc finger and homeodomain protein 3.
What is the protein family that this protein belongs to?
Belongs to the ZHX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSRR_YERPN
Sequence: MQLTSFTDYGLRALIYMASLPDGQMTSISQVTEVYGVSRNHMVKIINQLSRVGLVTAVRGKNGGIRLGKPADQILIGDVVRQMEPLTLVNCSSDFCHITPACRLKQVLNQAVQSFLKELDNYTLADMVKDNSPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: CTR3_RAT
Sequence: MLWQALRRFGQKLVRRRLLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKEKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISQTLKGTILLNMPHVLAEYPDFFALALVLLLTGLLVLGANESGLVTKVFTGMNLLVLGFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLMMPYYKLQPESPLPEAFTYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAFLFELTDLVDLMSIGTLLAYSLVSICVLILRYQPDQEMKNGEEEVELQEERTLEAEKLTVQALFCQVDSIPTLLSGRIVYVCSSLLAVLLTVLCLVLTWWTTPLHSGDPVWVTVVVLILGLILGISGVIWRQPQNRTPLHFKVPVVPLLPLVSIFVNVYLMMQMTADTWARFGVWMLIGFAIYFGYGIQHSVEEVKNHQTLPKTRPQTIDLDLTTSCVHSI
What is the function of this protein?
Uniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:9079705).  The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:9079705).
What are the official names of this protein?
Cationic amino acid transporter 3, CAT-3, CAT3, Cationic amino acid transporter y+, Solute carrier family 7 member 3.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECR_BDEBA
Sequence: MLHISALEKLVHELSRLPGIGPKTAQRLAYYILRTGNEYPERLSEALLRVKAEVHDCPTCFNYTDTDICRYCEDSHRSDESICVVEEPSDIMRIESSGAFRGRYHVLHGAISPLEGIGPKELKIKELIDRVEDGLSGTGPAIKEIILALDADLEGDTTILYLAKQLQGKGLKLSRIAHGVPIGSDIDFVDDRTMGRALQNRVEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RLMH_CALBD
Sequence: MIKIISVGTIKEKYFLQACEEYKKRLSRWVKVEEIEIKEEDENKYFNIETLLEKEADKILKHVKEGEFIIVCDINGIELSSEEFSEILRKNINSSKNITFIIGSSNGLSNEVKRRADLLLSFSKLTFPHQLFRVLLYEQIYRGLSIIYGTKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_CLOBM
Sequence: MAKYRAGRINEEVKKEVSSIIHNDIKDPRLSAMVSVTDVDVTKDLKYAKVYVSIFGNEKAKEESLQALKSSVGFIRKEIGRRVKLRNTPEVIIEVDNSIERGMHIDELLHSIKENKSNDN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THN_DENCL
Sequence: KSCCPTTAARNQYNICRLPGTPRPVCAALSGCKIISGTGCPPGYRH
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Denclatoxin-B.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_POLNS
Sequence: MRLTIVSVGHKMPDWVATATIEIKEIKPDLTLAKEAVKIAAAIPKGSRVIALDERGKDQTTQNLATQLASWRQEGFDITFLIGGADGLDPSLKTTAQAIWRLSSLTLPHAMARVLLVEQLYRAWTILQGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSHA_MYCS2
Sequence: MSETEREDERWTPPIGPIDPEHPECAAVIAEVWTLLDGECTPETRDKLKQHLEECPTCLRHYGIEERVKRLIAAKCSGEKAPDSLRERLRIQISRTTIIRG
What is the function of this protein?
A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH.  ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable).  Overexpression leads to increased susceptibility to diamide.
What are the official names of this protein?
Anti-sigma factor RshA, Regulator of SigH, Sigma-H anti-sigma factor RshA.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.
Protein: CNIH5_ARATH
Sequence: MGDLLDWIISFLFLATLIIIVIYQLTCLADLEFDRINPYDVSSRINRMVLPEFGLQGLLCLYYILTGHWFMAVLSLPHLFYNIRLYMKREHLADVTELYNTNKWEQKKRVYKIGHIALSIFITTYWLIHSALGDI
What are the official names of this protein?
Protein cornichon homolog 5.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: 2A5K_ARATH
Sequence: MFKQFLSKLPRKSSKSDSGELNRSSSGPVSSPVQRSGTSGGGSGPVRSNSGKRMSSAVFPASVVAGIEPLVPFKDVPSSEKLNLFVSKVSLCCVTFDFSDPGKNSIEKDVKRQTLLELLDFVASGSVKFTEPAILAMCRMCAVNLFRVFPPNYRSSSGGENDDDEPMFDPAWPHLQIVYDLLLKFITSPCLDAKVAKKYLDHAFIVRLLDLFDSEDPRERECLKTILHRVYGKFMVHRPFVRKSMSNIFYRFVFETEKHSGIAELLEIFGSIVSGFALPLKEEHKIFLWRVLIPLHKPKSVGNYFQQLSYCITQFIDKEPKLGSVVIKGLLKFWPITNSQKEVMFLGEVEEIVEAMSVMEFQKIMVPLFLRIACCVTSSHFQVSERALFLWNNDQIVNLIGHNRQAILPIMFTALEKNAQNHWNQSVLNLTLNVRKMFCEMDEALFMSCHARFKEDEAKQCSAAEKRKEVWARLENAASMKPITGKTAVLVTPRATSIAC
What is the function of this protein?
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform, AtB' kappa, PP2A, B' subunit, kappa isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIP_PIG
Sequence: YAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKSDWKHNITQ
What is the function of this protein?
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
What are the official names of this protein?
Gastric inhibitory polypeptide, GIP, Glucose-dependent insulinotropic polypeptide.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.