PharMolix/UniProtQA huggingface dataset:
Protein: DED1_SCHPO
Sequence: MSDNVQQQVDSVGSVTEKLQKTNISRPRKYIPPFARDKPSAGAAPAVGDDESVSSRGSSRSQTPSEFSSNYGGRREYNRGGHYGGGEGRQNNYRGGREGGYSNGGGYRNNRGFGQWRDGQHVIGARNTLLERQLFGAVADGTKVSTGINFEKYDDIPVEVSGGDIEPVNEFTSPPLNSHLLQNIKLSGYTQPTPVQKNSIPIVTSGRDLMACAQTGSGKTAGFLFPILSLAFDKGPAAVPVDQDAGMGYRPRKAYPTTLILAPTRELVCQIHEESRKFCYRSWVRPCAVYGGADIRAQIRQIDQGCDLLSATPGRLVDLIDRGRISLANIKFLVLDEADRMLDMGFEPQIRHIVEGADMTSVEERQTLMFSATFPRDIQLLARDFLKDYVFLSVGRVGSTSENITQKVVHVEDSEKRSYLLDILHTLPPEGLTLIFVETKRMADTLTDYLLNSNFPATSIHGDRTQRERERALELFRSGRTSIMVATAVASRGLDIPNVTHVINYDLPTDIDDYVHRIGRTGRAGNTGQAVAFFNRNNKGIAKELIELLQEANQECPSFLIAMARESSFGGNGRGGRYSGRGGRGGNAYGARDFRRPTNSSSGYSSGPSYSGYGGFESRTPHHGNTYNSGSAQSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).  Inactivation of ded1 blocks mitotic cell cycle progression at G1 and G2/M.  Induces sexual development and ascus formation.
What are the official names of this protein?
ATP-dependent RNA helicase ded1, Multicopy suppressor of overexpressed cyr1 protein 2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_BPPF1
Sequence: MSIKTLISVLRVTLLTACLLPSLFFVRSAIAGPYIWEVVMYSSSGSSTPAEACEKARVVADRSPDWNYTSATPKMNGLDNSYCSVVYVSRRDPSVVNTCDDCASWKLFRKGDQCANADDTYNASTGICEPPPKECKEGELFPAKGPDSPVVTSGGRNYVGDGGAPTACYQSCEYGGNPSPASCYLVKGSTTTGFCNYILKGTGQSCGADSYTFSQTGDSLNPPDTPNTDPSDPNDPGCPPGWSWSGTTCVKTPTDPTDPTDPTTPGGDGGGDGNGGGNNNGGGNDGGTGNGDGSGGGDGNGAGDGSGDGDGSGTGGDGNGTCDPAKENCSTGPEGPGGELKEPTPGTWDDAIATWEKKVEEAKKELKTKVKANVDQMKGAFDLNLAEGGGQLPCESMTIWGKSYSLCISDYAGQLSSLRVALLLMAALIAALILLKD
What is the function of this protein?
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process.  During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host type IV PAK pilus.  Subsequent interaction with the host entry receptor induces penetration of the viral DNA into the host cytoplasm.  In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal domain.
What are the official names of this protein?
Attachment protein G3P, Gene 3 protein, G3P, Minor coat protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G3P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass type I membrane protein. Note=Prior to assembly, G3P is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the head side of the filamentous virion.
Protein: FADA_ECOUT
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTTEMLARMHGISREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ALKOO
Sequence: MFGKLGTSELVLILGIALIIFGPGKLPELGKSLGKAISEFKSFSKEVKEDISLDDKKANNTLND
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LAMB_AERSA
Sequence: MKMKAKWLPIAAGVTAALASQAAFAVDFHGYFRSGVGVSTDGSMQTGLSDNAKQKVGRLGNEADTYGEIQLGSEVFNKDGKTFYVDSMVAMTSNGSNDWESTESKFQCTSANGTALDGCENKEDATFALRQFNVQAKGLLGFAPEATLWAGKRYYQRHDVHISDFYYWNISGRGAGIEGIQAGPGKVSFAWVRNDRSGTNVDGTYNDEMNVNTLDLRYAGIPLWQDGSLEVGVDYAIANPSDAQKDSANAQYKNAKDGVMLTAELTQGILGGFNKTVLQYGTEGYSKTFAFWGDRSWYGAEAKDGADGFRIINHGVIPMGNSWEMGHQLVYGVGNDMWDTNDKWETMSVVARPMYKWDDFNKTIFEGGYFKDKNKSTNGTSEEDAGYKLTLAQAWSAGSSFWARPEIRVFASYLAQDKKEMKGNAFNNGTADDTWNFGVQAEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: DEOB_STRPG
Sequence: MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISETAGLSVPNMVKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQLPEFTKGFSFTNLVDFDANFGHRRDSEGYRDCLHEFDNRLPEIIANMKEDDLLLITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFLGHLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZSWM2_MOUSE
Sequence: MLRGGCKASEKRRHLSESLSWQQDQALSSSIYLLRQIGPTGFLLKEEEPEKGDFRVLLGNPHECSCPTFLKRGELCKHICWVLLKKFKLPRNHESAFQLGLTEGEINDLLRGIHQVQAPQLRASDETAQVEEDGYLKQKDINAGDICPICQEVLLEKKLPVTFCRFGCGNNVHIKCMRILANYQDTGSDSSVLRCPLCREEFAPLKVILEEFKNSNKLITISEKERLDKHLGIPCNNCNQLPIEGRCYKCTECVEYHLCQECFDSCCHSSHAFASREKRNQRWRSVEKRSEVMKYLNTENEGEAKPGCFQEKQGQFYTPKHVVKSLPLLMITKKSKLLAPGYQCRLCLKSFSFGQYTRLLPCTHKFHRKCIDNWLLHKCNSCPIDRQVIYNPLIWKGIATDGQAHQLASSKDIACLSKQQEPKLFIPGTGLVLKGKRMGVLPSIPQYNSKVLTTLQNPSDNYQNITMDDLCSVKLDNSNSRKLVFGYKISKQFPTYLKNPTTGQTPSQTFLPSLPHKNIICLTGRESPHIYEKDHIGQSQKTSRGYEHINYNTRKSLGSRLRQHKRSSALSSEDLNLTINLGTTKLSLSKRQNNSMGKVRQKLGHPPRRPAYPPLQTQNAALSLIMQGIQL
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis.  Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.
What are the official names of this protein?
E3 ubiquitin-protein ligase Zswim2, MEKK1-related protein X, MEX, RING-type E3 ubiquitin transferase Zswim2, ZZ-type zinc finger-containing protein 2, Zinc finger SWIM domain-containing protein 2.
Protein: MURG_LACDB
Sequence: MRVIFSGGGTGGHIYPIMALIERLKEEGICQDDEILFVGTKKGLESKIVPAAGVNFKTIDIQGFDRKHLLNNVKTIQLFLKATKRAKEILADFQPDVVLGTGGYVSGAIVYEASKMKIPTMIHESNSVVGVANKFLGHYVDKICYTFDDAAKEFPEKKKLVKTGNPRSQQVLSLNAKPVDLAGDLGLNPKIPTVLVFGGSRGALAINRVMLKSLMELKKKPYQVIWATGTYYYDAIEKKLADVDYDDSIKVVPYIDNMPGLLPEMTCVVSRSGATSLAEFTALGVPVILIPSPNVTHNHQMKNAMDLEKAGAALVIAEDDLNENTFVSSIDHLLLDQSYDEKMRQASKALGVPDASDQVIKVMKEIAKKN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYSY_BRUC2
Sequence: MRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKENGVTIWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANLLKMLHTNPQSRSLIVSAWNPALVDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_ALBFT
Sequence: MLQPARRKYRKEQKGRNTGIATRGSSVAFGDFGLKCIDRGRLTARQIEAARRAISRHVKRGGRIWIRVFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKIVFEIVGVPEELAREAFRLAAAKLPLRTTFVARMIGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL20_FUSNN
Sequence: MRVKTGIIRRKRHKRVLKAAKGFRGASGDAFKQAKQATRRAMAFATRDRKVNKRRMRQLWITRINSAARMNGVSYSVLMNGLKKAGILLDRKVLADIALNNATEFTKLVEAAKSAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MTB_PARCR
Sequence: MDPCECSKSGTCNCGGSCTCTNCSCTSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein B, MT-B, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: ATSE_BACSU
Sequence: MNVKKITSEQDLHTAFEIRKAVFVEEQGCPISDEFDEFDTLHGDCQHILAYHQNVPVGTARVRIVGHTGKLERICILKSYRKFGLGKVIVDALERIVKEQGISAFKLHGQTQAAGFYEKLGYRTASEEFMLDGIPHVLMTKQDDSAL
What is the function of this protein?
Could catalyze the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product.
What are the official names of this protein?
Putative acetyltransferase BSU40680, GCN5-related N-acetyltransferase, GNAT.
What is the protein family that this protein belongs to?
Belongs to the UPF0039 (ElaA) family.
Protein: RL11_CHLTA
Sequence: MSNKKIIKIIKLQIPGGKANPAPPIGPALGAAGVNIMGFCKEFNAATQDRPGDLLPVVITVYSDKTFSFVMKQSPVSSLIKKALGLESGSKIPNRNKVGKLTRAQITVIAEQKMKDMDVVLLESAERMVEGTARSMGVDVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y210_GLAP5
Sequence: MATKSKYQDKQIEALLNDLIVTLEKHKAPVDLSLMALGNMITNILVTNVQSPQQREVLAEAFSSALKNSLKSAK
What are the official names of this protein?
UPF0352 protein HAPS_0210.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: ETCP_ENTFC
Sequence: MRKKLFSLALIGIFGLVVTNFGTKVDAATRSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGMGH
What is the function of this protein?
Bacteriocin that inhibits the growth of wide range of Gram-positive bacterial species.  Does not inhibit the growth of several strains of Gram-negative bacteria.
What are the official names of this protein?
Bacteriocin enterocin-P.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIA/YGNGV family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_METMP
Sequence: MSQKWGLVHIYASYNNTILHVTDLTGAETIAKVSGGMIVRNQRDESSPYAAMQAAFKIADLMRDKGIDQVHVKVRATGGQKSKNPGPGAQAAIRALSRAGIRIGRIEDATPIPHDGTTPKRKNR
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EFTS_BURM7
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMAKAEELLRVKLGNKASKAASRVTAEGVVASFVGANAGALVELNCETDFVAKNDDFNAFAKTVAELVATQNPADVAALSALPLDGKTVDEVRLALVGKIGENISIRRFVRFETSNKLATYLHGSRIGVIVEYTGAQEQVGKDVAMHVAAMKPVSLSADEVPADLIEKERRVAEQKAAESGKPAEIVAKMVDGSVQKFLKEVSLLNQPFVKNDKQTIEQMLKAADAAVQKFALFVVGEGIEKRQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_METC4
Sequence: MANTVSAKKMTRKIAKRTAINRSRRSRMRTFVRKVEEAIASGDQGQALTALRAAEPEIMRAAQNGIVHKNNASRKVSRLAARVKAIAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RF3_LACDB
Sequence: MNKELLDKVNKRRTFAIISHPDAGKTTITEQMLLLGGVIRSAGTVKARKTGNYATSDWMEIEKKRGISVTSSVMQFEYQGKRINILDTPGHQDFSEDTYRTLMAVDAAVMVIDSARGIEPQTKKLFKVVRQRGIPVFTFMNKLDRDGREPLDLVAELEEVLGIEGVAMNWPIGMGQSLLGLYDLANQRVELYHPEEGQDRFIALADGKAPAGSPLADDPQFEETLGEIELLEGAGASFDRAKVLAGQQTPVFFGSALTNFGVETFLEQFVDLAPAPGEHEVNGDEELKPDDDEFSGFIFKIQANMNPQHRDRIAFVRVCSGEFSKGLDVTLARTGKQVRLNNAVEFESSARVQVSEAVAGDIVGLYDTGNFQIGDSVYAGKRKLEFPPLPEFTPELFMRVSPKNVMKQKSFHKGMNQLVQEGAVQLYRNYQTDDYILGAVGQLQFEVFQYRMKNEYNSEVEMTSIGHRVARWINPDQLDPKMSSSRNLLVKDRFGNPLFLFENAFAERWFHDKYPDVELTEKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_BUCA5
Sequence: MKTPIYLDYAATTPVEFEVAKKMMNYLTIDGVFGNSASRSHKFGWKAEEVVDIARNQISELIGADSREIVFTSGATESNNLAIKGIASFHQNKGKHIVTSKTEHKSVLDTCRYLENKGFTVTYLTPKNNGIIDLNNLKKNIKKDTILVSIMHVNNEIGIIQDINSISQICRNHGVFFHVDATQSVGKIPIDLKKIPIDLMSFSAHKIYGPKGIGGLYVRRKPRVRLLSLIHGGGHERGMRSGTLPVHQIVGMGESFVLAKRKIHDDFIHLTKLKNILWNGIKNIEEVYLNSDLQQGAPHILNVSFNYVEGESLIMALKDLAISSGSACTSASLEPSYVLKSLGIRDELAHSSIRFSIGRFTTEKEIIHAIKLVHKSIHRLRELSPLWEMFKSGVDLNSIEWDHV
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTOP1_DANRE
Sequence: MVEHGGTDSMWLNKYNPAAASSASSSSSSDAENKLFSRLKVSLTKKYPQKNAELLSAQYGTNLLLLGVSVMLALAAQSGPVKEEHLLSFITVLMLVQLVWMLCYMIRRERERSPVPERDAHAGASWIRGGLTMLALLSLIMDAFRIGYFVGYHSCISAALGVYPIVHALHTISQVHFLWFHIKDVIKKYETFERFGVIHAVFTNLLLWCNGVMSETEHFMHNHRRRLIEMGYANLSTVDVQPHCNCTTSVCSMFSTSLYYLYPFNIEYHIFVSAMLFVMWKNIGRTLDRHSNRKRRSTGSTGLLLGPLGGLVALASSVSVLVVYLIHLEKTEEMHEAAVSMFYYYGVAMMACMCVGSGTGLLVYRMENRPMDTGSNPARTLDTELLLASSLGSWLMSWCSVVASVAEAGQKSPSFSWTSLTYSLLLVLEKCIQNLFIVESLYRRHSEEEEDAAAPQVFSVAVPPYDGILNHGYEAHDKHREAEPAAGSHALSRKQPDAPLPAGQRLDVTPGRKRQILKNICMFLFMCNISLWILPAFGCRPQYDNPLENETFGTSVWTTVLNVAIPLNLFYRMHSVASLFEVFRKV
What is the function of this protein?
Proton-selective channel that specifically transports protons into cells (By similarity).  Proton channel activity is only weakly-sensitive to voltage (By similarity).  Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes (By similarity).  In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration (PubMed:15480759, PubMed:15581873).  Probably acts by maintaining the pH appropriate for formation of otoconia (By similarity).  May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol (By similarity).
What are the official names of this protein?
Proton channel OTOP1, Otopetrin-1.
What is the protein family that this protein belongs to?
Belongs to the otopetrin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Detected in the gelatinous membrane overlying the inner ear macular epithelium.
Protein: TRM5_YARLI
Sequence: MKFNFWKGLWKPKSLTPTLSHRLYRRMYTPQPPLNREMTVLDRSKFTVSLNLALAKFPDPKYIAQFAKECKADILQLRSINHVQKTDDNGRAVLLRHDLDLEGGEDVASKVMSQLSPRGKELLTEAQADITKIVKDLDYDFWRADEIFYSVLPVTEKDEIPSGFSMVGHVAHLNLRSEWKDYDRLIGQVILDKNPRVKTVVNKVDSIDTKFRTFKMDVLAGEDNTEVEQHESGCRFQFDFAKVYWNSRLHTEHDRLVSLFRGEASSRERKQQERAKRENHEKSTETAVEPDNTPATAVCDVFAGVGPFAVPSGRTSLFVMANDLNPYSYEALEHNVKLNKVSEYVKCFNLDGAEYVQQSMKLLDEHRRTQPTINPVQVRKRKAGQPVVKQDIPNHYSHYVMNLPDSAIEFLWSFKGLYTTVDGLSQDTPLPHVHVHCFHKWEAGEEEPSKEETKAALLERVYKQIDVRLDPNEVGMHWVRKVSPKKDMFCISFELPKEVAWAPQVNKE
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: MDCG_PSESM
Sequence: MIDSAFVVLPHDLLWGMPLSALPDDAPQWAVDTLLAGQPVVVRRQAMPAGQVAVGLRGRGREQRYAASMWLTNVYRRVTPEQLIDCPSEHIQDWPALRALRQVRPVMDALERVWGVGGSAGFELASGIAALNQDSDLDLILRTPAPFSRRCAAELVEALAASVCRVDVQLQLDQGAVALREWARPAGRVLLKTASGARLVSDPWHLAEVCA
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: RL36_STAA8
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DPOE_EMENI
Sequence: MPSRKPSKYGNKFRSGAASFNPKRTKTVEFSSLRSSEATSQDEKFEAIRLANSIDESLGFPRFEAGEKRVGWLINMHSTSIEDPNVPGGRAGVDYYFLDDDGGSFKATVEYDPYFLIAVKTGHEAEVEEWCRRMFEGLIKKIKRVVKEDLKLPNHLLGHRRTFLQLDFANVSHLLEVRKTLLPLAEKNRKNARPNGTTNASDFIIDIREYDVPYHVRVAIDKDIRIGKWYTVEATHGIISLTCLEERLTRADPVVLAFDIETTKLPLKFPDSVIDQIMMISYMIDGQGFLITNREIVSEDIDDFEYTPKPEYSGPFMIFNEPNERAVIERFFEHIKEAKPTVIATYNGDFFDWPFVEARASVLGIDMYKEIGFRKNSEDIYQSDHCAHMDCFAWVNRDSYLPQGSRGLKAVTVAKLGYDPDELDPELMTPYASERPQTLAEYSVSDAVATYYLYMKYIHPFIFSLCTILPLNPDDTLRKGTGTLCEMLLMVQAYKGNIVLPNKHKDPPEAFYEGHLLESETYVGGHVESIEAGVFRSDIPVPFNIDPTAVDELLRDLDAALKFSIEVEEKKSLDDVTNYEEVKGQIAKLLTDLRENPHRNEVPFIYHLDVASMYPNIMITNRLQPDSLIQESNCAACDFNRPGKTCDRRLPWAWRGEFLPAKRDEYNMIRQAVQNERFPGRTKKSPMRAFTELSAEEQAAIVKKRLQDYSKKIYHKIHDSKTMVREAIICQRENPFYVDTVRSFRDRRYDFKGKQKVWKGKTESLKSSGAPAAEIEEAKKMIVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGVTCLTGARIIQMARELVERIGRPLELDTDGIWCMLPGTFPENFSFTLKNGKKLGISYPCVMLNHLVHGSYTNHQYQSLANPATFRYETHSENSIFFEVDGPYRAMILPTSKEEDKNLKKRYAVFNDDGSLAELKGFEVKRRGELKLIKIFQTQIFKFFLEGTTLAETYAAVARVADRWLDVLYEHGATLADEELIELISENRSMTKTLEEYGNQKSTSITTARRLAEFLGEQMVKDKGLNCKYIISARPRNTPVTERAIPVTIFSAEDSIKRHFLRKWLKDDPGDMDPRSVIDWDYYLERLGSVVQKLITIPAALQKIRNPVPRVAHPEWLQRRINKQDDRFKQVKMTDMFGKSEKNPLSDISTNIIDHRVQHADNLDEAMADSMEKLKSSSPQKASGKRKHPENQTKTSLDPFASLPAKMPSIDDDYVGFLKYQKQKWKIQKQARLRRRQLFGERANTGGDSLSHLFRNQAELLYISTWQVLQLAETSRPGIVRAFVLIDRKIHALTIKVPRCVYINLKQDSLPDVEVPECEVEKVNHTLPNGHPSVHLFKLTLSEETFLREADKIHVLLQHPSVEGVYERNIPLNLRAVLKLGSICTFDEAQRGVLGDGLERGFDLSTLCRTSSEQQYLQDSPLAYHFLYHVSSGEKQIFAIFSSTKNEAHIVILNRARDVQGLPNVDKIYSELLARKLQGQGDQAEGAFQYQEKIHFRTTQITTRRKAYLEVSDLIKKLRNDESLPAIMIIQSQQRSRLCHDIPILKEYPILSVKPEVSDMNLPPLGWQSFIAKRLVTHYLYLSSWVQHLTMLARYGDVPLCNLESDDPRFLIDISYARRLQQNNVVLWWSSTAKPDHAGYEKDDITGPLERVGMPCVNVPGSYTTVCVELEVRNLAINTILTSSIINEAEGADSLLAPSDPSAESSGSGVLYSEKAFASAGAVVLREMVKHWWSEACQGNNMADIMVQHLIRWVESPASCLYDRSLHQYVRMLSRKSFQQLMAEFRRVGSNVVFASPTRLLLQTSKTEVGNAYAYSQYVLKSIRANPSFHFIDLDIKEYWDYLVWYDEYNYGGKGCQEVAETEEQPLETVMHWQLSRFLPTPMQTIFHDWVVEYIELMHSFKRPESDDSSTPRLTQIPIGQPEPGQENEELSAALSDRFSKPLKKQISGLIRRQREELLHPELASDYVFPILPGVLTDPNEEKRNPVLELVKLLMQVLSLSKTTALETRLLRRELLALFEVREFSKEGRFENPGSSLKIPELTCSACCLIRDLDLCRDEDVLPERGSGSGPDSATSSRPWCCPFCQTEYDRLAQEEMLIGQVWGMVVAWQTQDLKCSKCGTLKISEFMEHCSCSGQWTETMNRADIEKRLKVLESVAKFHELKLLQVVVEEVLSQT
What is the function of this protein?
DNA polymerase II participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCIU_ECO24
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.