PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_CHESB
Sequence: MTGYILAIDQGTTSSRAVIFDGAMKIVAVGQKEFPQHYPASGWVEHDPEDIWKSVVATVKTALRKAKLEASRITAIGITNQRETAVIWDRATGMPIHNAIVWQDRRTAPLCAKLKKAGLEPKFTRKTGLLLDPYFSGTKFAWLLDNVKGARRRAEKGELLAGTIDTYLIWRLTGGRMHATDATNASRTLLYNISKNAWDADLLKILRIPTALLPEVKDCAAEFGVTEKKIFGAEIPILGVAGDQQAATIGQACFEPGMLKSTYGTGCFAVLNTGERLIRSKNRLLSTIAYRLDGKTTYALEGSIFIAGAAVQWLRDGIKVIGKAAESGALAERSDETQQIYLVPAFVGLGAPHWDADARGAIFGLTRNSGPAEFARAALESVAYQTHDLLVAMKRDCGNTFGKTVLRVDGGMVASSWTMQCLADILDAPVDSPTITETTALGAAWLAGSKAGIWPDRATFAKSWALERRFEPQMDGRQRKAKLAGWADAVSRTLTARAPC
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: CRTB_THET2
Sequence: MKMPASMEPDWKALLRVLRAHSATFYLGSLLFPKEARKGAWAVYAACRLGDEAVDGEGGGPEALEAWWAGVERAYRGRPLAEWEKGLAWALERWDIPFEAFLHMREGFLTDLGPVRLGTEAELLRYCYQVAGTVGRMMAPIAGGGKEAEARAVKLGQAMQLTNILRDVGEDLERDRVYLPLDLLRAHGVEVEDLRAGRVTPGYRALMAHLEGKARALYREGLAGLGHLKVGRAAIALAALQYRGILDKLRLSGYDNLGRRAHLKAWERALLLPKAFLAARFPPRPEGSP
What is the function of this protein?
Involved in the biosynthesis of carotenoids.  Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable).
What are the official names of this protein?
Phytoene synthase, PSase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
Protein: RSMH_STAAE
Sequence: MFHHISVMLNETIDYLNVKENGVYIDCTLGGAGHALYLLNQLNDDGRLIAIDQDQTAIDNAKEVLKDHLHRVTFVHSNFRELTQILKDLNIEKVDGIYYDLGVSSPQLDIPERGFSYHHDATLDMRMDQTQELTAYEIVNNWSYEALVKIFYRYGEEKFSKQIARRIEAHREQQPITTTLELVDIIKEGIPAKARRKGGHPAKRVFQALRIAVNDELSAFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVFQEYEKGPEVPRGLPVIPEAYTPKLKRVNRKPITATEEDLDDNNRARSAKLRVAEILK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX5_PICPA
Sequence: MSLIGGGSDCAAGSNPLAQFTKHTQHDTSLQQSMRNGEFQQGNQRMMRNESTMSPMERQQMDQFMQQQNNPAFNFQPMQHELNVMQQNMNAPQQVANNSWNQEFRMKDPMVANAPSAQVQTPVQSTNWAQDFQQAGPEVQHHAQQHQHPILSVPGVRAGIYGGGRLMGGSMMNRAAQMQQQNPAQAQTSEQSQTQWEDQFKDIESMLNSKTQEPKTKQQEQNTFEQVWDDIQVSYADVELTNDQFQAQWEKDFAQYAEGRLNYGEYKYEEKNQFRNDPDAYEIGMRLMESGAKLSEAGLAFEAAVQQDPKHVDAWLKLGEVQTQNEKESDGIAALEKCLELDPTNLAALMTLAISYINDGYDNAAYATLERWIETKYPDIASRARSSNPDLDGGDRIEQNKRVTELFMKAAQLSPDVASMDADVQTGLGVLFYSMEEFDKTIDCFKAAIEVEPDKALNWNRLGAALANYNKPEEAVEAYSRALQLNPNFVRARYNLGVSFINMGRYKEAVEHLLTGISLHEVEGVDASEMSSNQGLQNNALVETLKRAFLGMNRRDLVDKVYPGMGLAQFRKMFDF
What is the function of this protein?
Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) (By similarity).  Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins (By similarity).  PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle (By similarity).  Required for PEX7 ubiquitination (PubMed:25009284).
What are the official names of this protein?
Peroxisomal targeting signal receptor, PTS1 receptor, PTS1R, Peroxin-5, Peroxisomal protein PAS8.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).
Protein: Y2328_HALVD
Sequence: MTAADLPDDAVLVCIDMQVGFDDPAWGDRNNPEMEARVADLLAAWRAADRPVVHVRHDSAEPDSPLRSDGEGFAWKPEAEPVDGEPVFTKRVNSGFIGTDLEAWLRERDHSTLVVCGLTTDHCVSTTTRMAENLGFDVYLPADATATFDREGHDGERFSADEMHRTALAHLNREFATVVESADLSATR
What are the official names of this protein?
Uncharacterized isochorismatase family protein HVO_2328.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: RSMA_CUPPJ
Sequence: MRSNMHQGHVARKRFGQNFLVDDSIIHGIVNAINPLADDVLVEIGPGLGALTDPLLERVPQMQVVELDRDLVERLRRRYGDRLQVHAGDALAFDFGRLAVPGRPLRIVGNLPYNISSPLLFHLMDYADHVHDQHFMLQKEVVDRMVAEPGSKAFGRLSIMLQVRYHMEHVLDVPPGSFNPPPKVDSAVVRMIPWPRTESGRLRSPHADCDITVLGDLVTAAFSQRRKVLRNTLSFLRDQIDFEAIGFDLGRRAEEVPVGEYVELARRLGGDASDRSAA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALR_BERST
Sequence: MAIAERRSRSHLALRVRDRVSAEVFFEERFEDGWESKWVKSDWKRDENMAGEWNFTSGKWNGDANDKGIQTSEDYRFYAISAAFPEFSNKGKTLVFQFSVKHEQKLDCGGGYMKLLSGDVDQKKFGGDTPYSIMFGPDICGYSTKKVHAILTKGETNHLIKKDVPCETDQLTHVYTFILRPDASYSILIDNVEKQSGSVYTDWDILPPKQIKDPEAKKPEDWEDKEYIPDPEDKKPEGYDDIPKEITDPEAKKPEDWDDEEDGEWTAPTIPNPDYKGEWKPKKIKNPNFKGKWKAPMIDNPDFKDDPDIYVFPKLKYVGIELWQVKSGTMFDNVLICDDPDYAKKLAEETWGKNKDAEKAAFDEAEKKKEEEEAKDDPTESDDEKPDEEGESDGEGDDESKDIDNEEDDEDVHDEL
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle.  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS174_ARATH
Sequence: MGRVRTKTVKKSSRQVIEKYYSRMTLDFHTNKKILEEVAIIPSKRLRNKIAGFSTHLMKRIQKGPVRGISLKLQEEERERRMDFVPDESAIKTDEIKVDKETLEMLASLGMSDTPGISAVEPQQAMAPIAAFGGGRAPRRY
What are the official names of this protein?
40S ribosomal protein S17-4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: AZOR2_BURL3
Sequence: MRLLNIVSSPRGARSASIAVARAFVDAYRQTGATIDVDTLNVWEEDLPDFDSGAIGAKYKGVANAPMDEAEQSIWRRIQSLVKRFQDADRIVVGVPMWNFGYPYKLKQLIDLVSQRNMLFTFDGNAYAPLLEIPRALVIHVRGQSREPGAGADNPGFRHQADYIEFWLRFIGVSEVRSLTVEHTWGARASDSIERAQARAVEMAAEF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 2, Azo-dye reductase 2, FMN-dependent NADH-azo compound oxidoreductase 2, FMN-dependent NADH-azoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: SYM_HAMD5
Sequence: MTESIKKILVTCALPYANGPIHLGHMLEHIQADIWVRYQRMRGHEVYFICADDAHGTAIMLKAEKSGINPEKMIEEINQQHQNDFSGFLISYDHYYSTHSDENRELSVAIYQRLKAKGHIKKRAISQLYDPEKKLFLPDRFVKGTCPKCQAPNQYGDNCEACGSTYSSTELIAPKSEVSGATPVIRESEHFFFDLPAFTGMLTQWIHSGALQEQVANKMQTWLTSGLRQWDITRDTPYFGFEIPDAPDKYFYVWLDAPIGYMGSFKNFCDKKENVSFDEFWQTDTKTELYHFIGKDIVYFHSLFWPAVLEGSDFRKPTNLFVHGYITVNGAKMSKSRGTFIEASDYLKHLDPDCLRYYYAAKLSSHIDDIDLNLEDFVQRVNADLVNKVVNLAARNASFINKKFAGILSKELADSELYFTFVQAGLRIANAYHARETSKAIREIMALADLANRYVDEQAPWVLAKKEVDEAKLQSVCSMGIHLFRILMTYLKPVLPALSERSEAFLNTELTWDSINEPLLNHEIKPFKALFNRIDNDKIVAMLKC
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_SHEHH
Sequence: MPELPEVEVTRQGVSPYLIDNQVTDLIVRNPSLRWPVPEIAKQIIGQTIRNVRRRGKYLLIDTDAGTTIVHLGMSGSLRILPASTPVEKHDHIDLVLASGKALRFNDPRRFGAWLWCELPEQAHPLLSKLGPEPLTDAFNAPYLLAALANKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPQAEAGKVDAERIEILVSEVKQILASAIKQGGTTLKDFTNADGKPGYFAQKLHVYGRGGETCTQCGHLLSEIKLGQRATVFCSLCQKL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RUVA_BRUA2
Sequence: MIGKLKGVIDEIAEDHAVIDVHGVGYVAFCSARTLGNLGGAGEAAILFIETYVREDMIRLYGFATQLEREWFRLLQNVQGVGAKVALAVLGTLSPSELANAIALRDIAMVSRAPGVGKKVAERIVTELKNKAPAFAGEASGTIGLKQELGAGAAPAPVADAVSALSNLGYSRDQAANAVAAALKETGEGADSAKLIRLGLKELSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RUTD_ECO45
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLVQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: LEXA_RHORT
Sequence: MLTRKQYLLLSFIDQRLKLSGVSPSFDEMKDALGLKSKSGIHRLIKGLEERGFLKRLPHRARALEVLRLPCNLTFDGDGEALDDGQPAPLFGGPLPETGFSPQVIRGNFTPTLPSTQVPQVLFTESISLPLLGKIAAGTPIAALIDPTSSIDVPASMVRGGEHFALRIEGDSMIEAGILSGDLAVVRRCDEAENGTVIVALVDNEEATLKRLRRKGASIALEPANRAFKTQIYGPDRVRIQGRLVGLIRSY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: YQGF_CLOAB
Sequence: MRILGIDVGNKTIGVALSDPLGFTAQGITTIRRKNEEEDIKELKELCEKYEVDTIVCGLPKNMNGTIGFQSEKVLGFCEVIKQNINVPIKMWDERLTTVTANRAMLEADLSRKKRKKLVDKVAATYILQGYLNSI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3_STRPG
Sequence: MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYENDKLIIAAPRFVNNDHFRKNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKAPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGVATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSDGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB36_ARATH
Sequence: MGRAPCCDKANVKKGPWSPEEDVKLKDYIDKYGTGGNWIALPQKIGLKRCGKSCRLRWLNYLRPNIKHGGFSEEEDRIILSLYISIGSRWSIIAAQLPGRTDNDIKNYWNTKLKKKLLGRQKQMNRQDSITDSTENNLSNNNNNKSPQNLSNSALERLQLHMQLQNLQSPFSSFYNNPILWPKLHPLLQSTTTNQNPKLASQESFHPLGVNVDHQHNNTKLAQINNGASSLYSENVEQSQNPAHEFQPNFGFSQDLRLDNHNMDFMNRGVSKELFQVGNEFELTNGSSWWSEEVELERKTTSSSSWGSASVLDQTTEGMVMLQDYAQMSYHSV
What is the function of this protein?
Transcription factors that activates genes required for endodermal differentiation but represses genes involved in proliferative divisions, thus regulating the transition from proliferation to differentiation in root endodermis (PubMed:26371322).  Required for Casparian strip formation by positively regulating the expression of the Casparian strip genes CASP1, PER64 and ESB1 and other endodermis-specific genes, thus triggering correct localized lignin biosynthesis in root endodermis and subsequently regulating global ion homeostasis (PubMed:26124109, PubMed:26371322).
What are the official names of this protein?
Transcription factor MYB36, Myb-related protein 36, AtMYB36.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_BACC2
Sequence: MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFVVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGRKSEDLIVKVPPGTIVKDEKTGQILADLVTHEQTAVIARGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVIVHVIDMSGLEGREPYEDYVTINNELKEYNMRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDLLFEVANLLETTPEFPMYDVVEESEASVMYKFDAESLKFEITRESDGTFVISGYDIEKTFKMTDFSRDESIRRFARQMRGMGIDEALRARGAKDGDIVKILEYEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCA_SCHPO
Sequence: MFKTQTTLLTSLRRFSSSSQLKNSKSLYEQTIPNLMINSDTKVIFQGFTGKQGTFHAQHAMDYGTKVVGGTNPKKAGTTHLGKPVFGTIEEAMKETKADASAVFVPPPLAAGAIEEAIAAEVPLIVAITEGIPQHDMLRVSDILKTQSKSRLVGPNCPGIIRPGQCKIGIMPSHIHKPGCIGIVSRSGTLTYEAVNQTTQTDLGQSLVIGIGGDPFPGTNFIDALKLFLDDPNTQGIILIGEIGGSAEEDAAEFIRAANASRSTPKPVVSFIAGATAPKGRRMGHAGAIVAGGKGTAAAKFEALEAAGVRISRSPATLGSLIVEELNKLKH
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2286_MYCTO
Sequence: MTTVDFHFDPLCPFAYQTSVWIRDVRAQLGITINWRFFSLEEINLVAGKKHPWERDWSYGWSLMRIGALLRRTNMSLLDRWYAAIGHELHTLGGKPHDPAVARRLLCDVGVNAAILDAALDDPTTHDDVRADHQRVVAAGGYGVPTLFLDGQCLFGPVLVDPPAGPAALNLWSVVTGMAGLPHVYELQRPKSPADVELIAQQLRPYLDGRDWVSINRGEIVDIDRLAGRS
What are the official names of this protein?
Uncharacterized protein MT2344.
Protein: TYRDC_ENTFC
Sequence: MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDMPAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALLAYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMADGWGHIAADGSIANLEGLWYARCIKSIPLAVKEVLPEKVKNMSEWALLNLSVEEILEMTESFTDEEMDEVKAASSRSGKNIQKLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELADQKIPILGVVAVVGTTEEGQVDSVDKIIQLREKLKDEGIYFYLHVDAAYGGYARSLFLNEAGEFVPYASLAEFFEEHHVFHHYVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYAAGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLPLNVTGYGQLIGASIEAAQRFREFLEQLHFTVKGKTIEVYPLNHPDFNMVNWVFKVQDCTDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFIERMGLSKEEWQKEQQITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIK
What is the function of this protein?
Also involved in drug metabolism, being able to catalyze decarboxylation of levodopa (L-dopa) to dopamine.  In gut microbiota this enzyme is in fact exclusively responsible for the decarboxylation of levodopa, and thus reduces in situ levels of levodopa in the treatment of Parkinson's disease.  It was shown that abundance of bacterial tyrosine decarboxylase in the proximal small intestine - the primary site of levodopa absorption - contributes to interindividual variation in drug efficacy and can explain the requirement for an increased dosage regimen of levodopa treatment in Parkinson's disease patients.
What are the official names of this protein?
L-tyrosine decarboxylase, TDC, Levodopa decarboxylase, L-dopa decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Tyrosine decarboxylase subfamily.
Protein: FTSH_HELAN
Sequence: NSALWPVAGEAEVPFISCSASEFVELYVGMGASRVRDLFARAKKEAPSIIFIDEIDAVAKSRDGRFRIVSNDEREQTLNQLLTEMDGFDSNSAVIVLGATNRADVLDPALRRPGRFDRVVMVETPDRVGRQAILNVHVSKKELPLGDDVDLASIASMTTGFTGADLANLVNEAALLAGRQNKVVVEKIDFIHAVERSIAGIEKKTAKLQGSEKAVVARHEAGHAVVGTAVSKLLAGQPRVEKLSILPRSGRALGFTYTPS
What is the function of this protein?
Probable ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH, chloroplastic.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Protein: THSB_THEK1
Sequence: MAQLAGQPVVILPEGTQRYVGRDAQRLNILAARIIAETVRTTLGPKGMDKMLVDSLGDIVITNDGATILDEMDIQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLRKAEELLDQNIHPSIIIKGYALAAEKAQEILDEIAKDVDVEDREILKKAAVTSITGKAAEEEREYLAEIAVEAVKQVAEKVGETYKVDLDNIKFEKKEGGSVKDTQLIKGVVIDKEVVHPGMPKRVEGAKIALINEALEVKETETDAEIRITSPEQLQAFLEQEEKMLREMVDKIKEVGANVVFVQKGIDDLAQHYLAKYGIMAVRRVKKSDMEKLAKATGAKIVTNVRDLTPEDLGEAELVEQRKVAGENMIFVEGCKNPKAVTILIRGGTEHVVDEVERALEDAVKVVKDIVEDGKIVAAGGAPEIELSIRLDEYAKEVGGKEQLAIEAFAEALKVIPRTLAENAGLDPIETLVKVIAAHKEKGPTIGVDVFEGEPADMLERGVIAPVRVPKQAIKSASEAAIMILRIDDVIAASKLEKDKEGGKGGSEDFGSDLD
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit beta, Chaperonin subunit beta, Thermosome subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: UGT2_DACCO
Sequence: MEFRLLILALFSVLMSTSNGAEILALFPIHGISNYNVAEALLKTLANRGHNVTVVTSFPQKKPVPNLYEIDVSGAKGLATNSIHFERLQTIIQDVKSNFKNMVRLSRTYCEIMFSDPRVLNIRDKKFDLVINAVFGSDCDAGFAWKSQAPLISILNARHTPWALHRMGNPSNPAYMPVIHSRFPVKMNFFQRMINTGWHLYFLYMYFYYGNGEDANKMARKFFGNDMPDINEMVFNTSLLFVNTHFSVDMPYPLVPNCIEIGGIHVKEPQPLPLEIQKFMDEAEHGVIFFTLGSMVRTSTFPNQTIQAFKEAFAELPQRVLWKFENENEDMPSNVLIRKWFPQNDIFGHKNIKAFISHGGNSGALEAVHFGVPIIGIPLFYDQYRNILSFVKEGVAVLLDVNDLTKDNILSSVRTVVNDKSYSERMKALSQLFRDRPMSPLDTAVYWTEYVIRHRGAHHLKTAGAFLHWYQYLLLDVITFLLVTFCAFCFIVKYICKALIHHYWSSSKSEKLKKN
What is the function of this protein?
Membrane-bound UDP-glucosyltransferase (UGT) which catalyzes the C-glucosylation of kermesate and flavokermesate to produce carminate and flavokermesate 7-C-beta-D-glucoside (dcll) respectively (PubMed:29215010).  Carminate is used as a deterrent against insect predators (PubMed:29215010).
What are the official names of this protein?
UDP-glucosyltransferase 2, DcUGT2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Localization to the endoplasmic reticulum membrane is critical for its activity.
Protein: YEY4_SCHPO
Sequence: MTGATLTVRVIRNFEYRTLKNVVFHDIDLATTTVDQFKKIIDERIQTDPSLKIYRTTHFDTLKIYVKAQQHKTQNLAINLDHDDWILNDGAKTLSLCGIENETELSYFELAAYKAYQANPVQKWL
What are the official names of this protein?
UPF0538 protein C2C4.04c.
What is the protein family that this protein belongs to?
Belongs to the UPF0538 family.
Protein: Y2490_SHESR
Sequence: MAFDKKLLDIVACPVCKGKLEYDKTTQQLICKADKLAYPITDGIPVLLENRAVPLNEAV
What are the official names of this protein?
UPF0434 protein Shewmr7_2490.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: KTHY_BACAH
Sequence: MKGLFVTIEGPEGSGKTTLIQSLLPYFEQKEQKVMATREPGGIAISEDIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALNDDYLVLCDRFIDSSLAYQGYARGLGMDKVFEINRFATEDCMPSLTIYLDIEPEVGLARIAKDAGREVNRLDMEDISFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVIQVIEDKLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.