PharMolix/UniProtQA huggingface dataset:
Protein: RS14_PORGI
Sequence: MAKESMKAREVKRAKLVAKYAAKRAALKAEGNYEALQLLPKNASPVRLHNRCSMTGRPKGYMRQFGISRIQFREMASAGLIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RSGA_BACFN
Sequence: MKGLVIKNTGSWYQVKTDDGQLVECKIKGNFRLKGIRSTNPVAVGDRVQIILNQEGTAFISEIEDRKNYIIRRSSNLSKQSHILAANLDQCMLVVTVNYPETSTTFIDRFLASAEAYRVPVKILFNKVDAYDEDELHYLDSLITLYTQIGYPCFKISALTGEGVDAIREELKGRVTLFSGHSGVGKSTLINALVPGLEVKTAEISAYHNKGMHTTTFSEMFPVPGDGYIIDTPGIKGFGTFDMEEEEIGHYFPEIFKTSANCKYGNCTHRQEPGCAVRKAVEEHYISESRYTSYLSMLEDKEEGKYRAAY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BREBN
Sequence: MSKDQILEAIKGMSVLELNDLVKAIEEEFGVTAAAPVAVVAGGGAEAAAEQTEFTVNLVSGGASKINVIKVVRELTGLGLKEAKDLVDNAPKTLKEGVSKDEAEALKAKLEEAGAQVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HLDE_SALNS
Sequence: MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSVQTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVASARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANGGEVMVLNFEDGCSTTNIIKKIQTESEK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CBP4_CANGA
Sequence: MDTPVWRRWLKIYIYGGSIILGGVLLFKYTTPTDEKLIASLSPELRLQYEKERKLRQEEQRELMRIVQETAKSNEPIWKTGPIDSPWEKKKGGEVVKNENFFDKIQKTRAEEAQKDELQRIREELDSLRAQSMKKTSDIVNERKSKDWWKIW
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NUSB_AQUAE
Sequence: MRYRKGARDTAFLVLYRWDLRGENPGELFKEVVEEKNIKNKDAYEYAKKLVDTAVRHIEEIDSIIEKHLKGWSIDRLGYVERNALRLGVAELIFLKSKEPGRVFIDIVDLVKKYADEKAGKFVNGVLSAIYKAYITSSKEEKPSLKSE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: THIE_PROMP
Sequence: MKNPNIIQPEDLRISQIIDANLDRAREGLRVLEDWARFGLGNEDFVIRIKNFRQILGKNHLEIYKLSRNHIEDQCKGLSHVEQINRNSSSKIISSNSARVQEALRVIEEFSRIHNSKLSKIASEIRYEIYTLEIEILNFNTRKRAQSIISKNNLYSITDPRENLLEIIEKILLGGVKIIQHRFKEGNDKDHLKEAIEINKLCKKYNSLFIVNNRLDIALASKADGVHLGQDDLDIKTVRKLLGASKIIGVSANNSTDINKAVKDGCDYIGVGPVFPTLTKKNKEPLGEEKIKALTKELNIPCFAIGGINKLNISSLKNHGISKVAIVSGLLNSEDPKDEAMIIIKELSHEN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: COX3_USTMA
Sequence: MNTQLSRTQFQFQPFHLVTPSPWPLLTSFALLILTSAAVMYFNGYANPLGGSGALLVGIGLATTVAAMALWFRDVVAEGTFLGDHTILVQKGITMGVALFIISEVFFFISVFWAFFHSSLSPTVELGAQWPPVGIATINPFELPLLNTILLLSSGATVTYAHHSVIEGNRRGAILGTLMTLIFAVLFTICQGIEYLNAGFTIADGVFGSTFFFSTGFHGVHVIIGTLFIAVAFFRMLSYHLTDHHHLGFEASILYWHFVDVVWLFLFISVYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PUR5_ACIB5
Sequence: MSNSTSTPNTGLSYKDAGVDIEAGDALVDRIKSVAKRTTRPEVMGGLGGFGALCKIPKGYEEPVLVSGTDGVGTKLRLALNLNRHDTIGQDLVAMCVNDLLVCGAEPLFFLDYYATGHLNVDVAANVVTGIGKGCELAGCALVGGETAEMPGMYEGEDYDLAGFAVGVVEQSKIIDGSKVKSGDVLIGVASSGAHSNGYSLLRKILDVKNVDLTQVIDGRPLADVAMEPTRIYVKPVLELCKQVDVHAMAHITGGGLPGNLPRVLPNGAQAVINEASWEWPELFKLLQREGNVERFEMYRTFNCGVGMVIAVDANDAEKAIEVLNAQGEKAWKIGHIQENAESVEGADEKIRVIFE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_ABIHO
Sequence: MSTIISYFGFLLASIIFTLILFISLSKIQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PSYC_OIKKI
Sequence: INNWVRVPPCDQVCSRTNPEKDECCRAHGHAFHATCSGGMQCYRR
What is the function of this protein?
Has antimicrobial activity.  Is particularly active against fungi, and to a lesser extent against Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Psychimicin.
What is the protein family that this protein belongs to?
Belongs to the diapausin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_CHLL3
Sequence: MRNIRLRVEYDGTPYAGWQRQPGGIVTVQGELEACLSRILQERVNLAAAGRTDRGVHALGQVVNFQTASSLELQRIAHSLNCLLPDTIRVDCPQEVDMEFHARFSAAERQYRYFLMEEPSAVFGRFAGCSSRPLDLPLMHSLAVTLKGIHDFSAFSREDRDGTGSLCSVRMAGWYRHRGFLVFHIAANRFLRSMVRGLVGAMMDIGAGRLDPCSFKAMLDADAHARRVRPAAASGLFLSRVVYPDDYGCRKLR
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NADD_CLOBL
Sequence: MINKAILGGTFDPIHNAHINVAYEALERFNLEEVIFIPAGNPPHKINLKKTPAHIRYEMVKLAIEKETRFSISDFEIKSKGLSYTYRTLKHFKEKEPETNWYFITGEDCLSYLEHWKYIDEIFNICNFVIFSREGFKEKEEIIKKKKSILLKYRKEILFMDASILDISSTKIRNRIKEGKEVSFYMPDKVYKFILQNNLYK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y1496_METJA
Sequence: MQNKKIKKVKVGNLEFEVVLADNFIKRAFGLMLRDIGDKAMLFLYKRRKIAMHTFFMLYPIDIIFIDKNRVVEAVRLKPWKTYKCKNYSTAMLEFKCSDIDLNEIIGEKVEFMR
What are the official names of this protein?
UPF0127 protein MJ1496.
What is the protein family that this protein belongs to?
Belongs to the UPF0127 family.
Protein: ARNA_SALSV
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNDGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLDWEPSIAMRDTVEETLDFFLRSVDIAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: PAL1_RUBID
Sequence: MEFYKNGNGAVESFCEGHDPLNWNMAAESLKGSHVDELKRMVSDYRKPVVKLGGETLTIGQVAAIASHDGGVRVELSEEKRAGVKASSDWVMDSMGKGTDSYGVTTGFGATSHRRTKNGGALQRELIRFLNAGIFGSSLDSTHKLPHTATRAAMLVRFNTLLQGYSGIRFEILEAITKFLNGNITPCLPLRGTITASGDLVPLSYIAGLLIGRPNSKSVGPKGETLSPAEGFKLAGIDGGFFELQPKEGLALVNGTAVGSGMASMVLFDANTLAVLSEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILEGSSYVKEAKKVHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKALHGGNFQELPIGVAMDNTRLAIASIGKLIFAQFSELVNDYYNNGLPSILTGSSNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVDILKLMSSTFLVALCQAIDLRHLEENLKIVVKTTVSNVAKRTLTVSPNGELHPSRFSEKDLLTVVDREYLFSYIDDPCLATYPLMQKLRAELVEHALKNGERERSANTSIFHKIAAFEEELKTILPKEVDNARIEIENGKSEIPNRIKECRSYPLYRFVREELGTSLLTGEKIKSPGEECYKVFNAICAGKLVDPLLECLKEWNGAPLPIS
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase 1, RiPAL1.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN761_HUMAN
Sequence: MAFSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCTMKEFLSTAQGNREVFHAGTLQIHESHHNGDFCYQDVDKDIHDYEFQWQEDERNGHEAPMTKIKKLTGITERYDQSHARNKPIKDQLGSSFHSHLPEMHIFQTEEKIDNQVVKSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEKQV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 761.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_MYCGE
Sequence: MLNNQQIHQSVLINEVIHNLNINPCGNYLDLTAGFAGHSQKILEKLTTGTLTINDVDKESINFCQKLFFKNNNVVIIHDNFANFPVHLKQLSITKFDGILMDLGVSSHQLNQPNRGFSFKNDGPIDMRMDQSNQKNTALTVLKNLTEQKLSLILKKYGDIKHPKPIAIGLKKAVQTEKNLTTTQLAKVVKECATGFEKYQSRNYLAKVFQAIRIYLNDEITNLKTALTFIPNLLKNNSRFLVIVFHSIEEKIVRNFIAKLTSFIQPEALPIKLTPAYQLITKKPILPSQKELELNPRSRSAKLFVIQKN
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_ECO8A
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: FOLD_AFIC5
Sequence: MPATRIDGKAIAAKLREDVAAEVARLKRDHDLTPGLAVVLIGNDPASEVYVGSKTKQTVAAGMASFEHKLAADTPQAQVLALIARLNRDPAVHGILVQLPLPKGLDATIIVNAIDPAKDVDGLHPVNAGRLASGLPALTPCTPLGCIILAKTVHASLEGMNAIVLGRSNLVGRPLVQLLLNENATVTIAHSRTRNLPALCRQADLVFAAVGRPEMVKGDWIKPGATVIDVGINRLPGEGGKSRLVGDVAYAEAMEVAGAVTPVPGGVGQMTVACLLVNTVRAACAIKGLSAPSV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL3_METB6
Sequence: MPKINRPRRGSLAFSPRKRAQSPIPKYKSWPEHSGAPALLGFAGYKVGMTHVLMVDDHKDSPTEGKEIMVPVTIIEIPTMKVAALRVYTKDTYGKHALTEIWAEPLDSQLSRRVTSPKNYDSTAAKKKYSDALAAGLVAEIYALAYTQPATMSGVPKKVPDLMEIKVAGGDIAKQYEYAFGLLGKEIRLSNVIETGAYADITAITIGKGTQGPVKRWGVTLRKRKHSVGGKERHVGTLGPWNPHHVRWEVPQSGQMGYQQRTEFNKRILKIGENGAEITPAGGFLNYGVIRNAYVVIKGSIPGPAKRLIRIRPAIRQGEHVVRSPAIQFVSVQSKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: O165_CONLI
Sequence: MKLTCALIVAMLFLTACQLTTTDDSRGRQKYPTERLRVKMRNPKLSKLTKTCDPPGDSCSRWYNHCCSKLCTSRNSGPTCSRP
What are the official names of this protein?
Conotoxin LiCr95.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_SHIDS
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACMALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: VDAC1_BOVIN
Sequence: MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDVDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane and also the plasma membrane.  The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis.  It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective.  Binds various signaling molecules, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol.  In depolarized mitochondria, acts downstream of PRKN and PINK1 to promote mitophagy or prevent apoptosis; polyubiquitination by PRKN promotes mitophagy, while monoubiquitination by PRKN decreases mitochondrial calcium influx which ultimately inhibits apoptosis.  May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.  May mediate ATP export from cells.
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 1, VDAC-1, Brain-derived voltage-dependent anion channel 1, BR1-VDAC, Plasmalemmal porin.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: RISB_CLOBJ
Sequence: MKIYEGRLTAEGLKVGIIVSRFNEFITSKLLAGSIDCLKRHGAKEDNIEVCWVPGAFEIPVIAKKMASKGKYDAVICLGAVIRGATPHFDYVSSEVSKGVAHVSLDKEVPVIFGVLTTDTIEQAIERAGTKAGNKGYDAAMSAIEMSNLMKVLD
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DCUP_AERS4
Sequence: MKELKNDRYLRALLRQDVDMTPVWMMRQAGRYLPEYKATRAVAGDFMSLCRNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEQGEGPRFERPIKSMADVQALPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKIKQMMYAEPQTLHLLLDKLADSVIGYLNAQIKAGAQSVMVFDTWGGVLTPRDYRDFSLQYMHKIVDGLIRENEGRRVPVTLFTKNGGQWLEQIAATGCDALGLDWTIDIADAKRRVGDKVALQGNMDPSMLYAAPARIREEVATILAGFGSGNGHVFNLGHGIHQDVDPEHAGVFVNAVHELSAQYHGR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_VIBCH
Sequence: MSEVITQEYTEDGKVLRRIRSFVRREGRLTKGQEAAMKECWPTMGIDYQPELLDWQQVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHDAVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLMIGSGVFHMATDWENYAEHMVEVMNQAPGFANLATDGDYVPRPDERPLTKFEQRGHRLGHGVWDIKYQRTA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MLTC_CITK8
Sequence: MKKFFALALVAPLLISCSSSTKKGDTYNEAWVKDTNGFDILMGQFAHNIENLWGFKEVLIAGPKDYVKYTDQYQTRSHINFDDGTITVETIAGTEPAAHLRRAIIKTLLMGDDPGSVDLYSDVDDIQISREPFLYGQVVDNTGQPIRWEGRATNFADYLLKTRLKSRSNGLRIIYSVTINLVPNHLDKRAHKYVGMVRQAARKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPGRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKVQAANIINSMSPGDVYQTLTTRHPSAESRRYLYKVNATQKSYRRK
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.