PharMolix/UniProtQA huggingface dataset:
Protein: MECR_HUMAN
Sequence: MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II).  Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro.  Displays a preference for medium-chain over short- and long-chain substrates (PubMed:18479707, PubMed:12654921, PubMed:27817865).  May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase, mitochondrial, 2-enoyl thioester reductase, Nuclear receptor-binding factor 1, HsNrbf-1, NRBF-1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: ATS7_MOUSE
Sequence: MHRGPSLLLILCALASRVLGPASGLVTEGRAGLDIVHPVRVDAGGSFLSYELWPRVLRKRDVSTTQASSAFYQLQYQGRELLFNLTTNPYLMAPGFVSEIRRHSTLGHAHIQTSVPTCHLLGDVQDPELEGGFAAISACDGLRGVFQLSNEDYFIEPLDGVSAQPGHAQPHVVYKHQGSRKQAQQGDSRPSGTCGMQVPPDLEQQREHWEQQQQKRRQQRSVSKEKWVETLVVADSKMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHISIVRLIILEDEEKDLKITHHAEETLKNFCRWQKNINIKGDDHPQHHDTAILLTRKDLCASMNQPCETLGLSHVSGLCHPQLSCSVSEDTGMPLAFTVAHELGHSFGIQHDGTGNDCESIGKRPFIMSPQLLYDRGIPLTWSRCSREYITRFLDRGWGLCLDDRPSKDVIALPSVLPGVLYDVNHQCRLQYGSHSAYCEDMDDVCHTLWCSVGTTCHSKLDAAVDGTSCGKNKWCLKGECVPEGFQPEAVDGGWSGWSAWSDCSRSCGVGVRSSERQCTQPVPKNRGKYCVGERKRSQLCNLPACPPDRPSFRHTQCSQFDGMLYKGKLHKWVPVPNDDNPCELHCRPSNSSNTEKLRDAVVDGTPCYQSRISRDICLNGICKNVGCDFVIDSGAEEDRCGVCRGDGSTCQTVSRTFKETEGQGYVDIGLIPAGAREILIEEVAEAANFLALRSEDPDKYFLNGGWTIQWNGDYRVAGTTFTYARKGNWENLTSPGPTSEPVWIQLLFQEKNPGVHYQYTIQRDSHDQVRPPEFSWHYGPWSKCTVTCGTGVQRQSLYCMERQAGVVAEEYCNTLNRPDERQRKCSEEPCPPRWWAGEWQPCSRSCGPEGLSRRAVFCIRSMGLDEQRALELSACEHLPRPLAETPCNRHVICPSTWGVGNWSQCSVTCGAGIRQRSVLCINNTDVPCDEAERPITETFCFLQPCQYPMYIVDTGASGSGSSSPELFNEVDFIPNQLAPRPSPASSPKPVSISNAIDEEELDPPGPVFVDDFYYDYNFINFHEDLSYGSFEEPHPDLVDNGGWTAPPHIRPTESPSDTPVPTAGALGAEAEDIQGSWSPSPLLSEASYSPPGLEQTSINPLANFLTEEDTPMGAPELGFPSLPWPPASVDDMMTPVGPGNPDELLVKEDEQSPPSTPWSDRNKLSTDGNPLGHTSPALPQSPIPTQPSPPSISPTQASPSPDVVEVSTGWNAAWDPVLEADLKPGHGELPSTVEVASPPLLPMATVPGIWGRDSPLEPGTPTFSSPELSSQHLKTLTMPGTLLLTVPTDLRSPGPSGQPQTPNLEGTQSPGLLPTPARETQTNSSKDPEVQPLQPSLEEDGDPADPLPARNASWQVGNWSQCSTTCGLGAIWRLVSCSSGNDEDCTLASRPQPARHCHLRPCAAWRTGNWSKCSRNCGGGSSTRDVQCVDTRDLRPLRPFHCQPGPTKPPNRQLCGTQPCLPWYTSSWRECSEACGGGEQQRLVTCPEPGLCEESLRPNNSRPCNTHPCTQWVVGPWGQCSAPCGGGVQRRLVRCVNTQTGLAEEDSDLCSHEAWPESSRPCATEDCELVEPPRCERDRLSFNFCETLRLLGRCQLPTIRAQCCRSCPPLSRGVPSRGHQRVARR
What is the function of this protein?
Metalloprotease that may play a role in the degradation of COMP.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAM-TS 7, ADAM-TS7, ADAMTS-7, COMPase.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Also found associated with the external cell surface.
Protein: THIM_HELPG
Sequence: MVLKELRQKRPLVHNITNYVVAQFVANGLLALGASPLMSDAIDEMQDLAKISDALAINIGTLNERTILCAKEAIKHYKALNKPIVLDPVGCSASALRHDTSLELLESEGISALRGNAAELGSLVGISCESKGLDSHDATTPVEIIKRAAQKYSVIAVMTGKTDYVSDGKKVLSITGGSEYLALITGAGCLHAAACASFLGLKKDPLDSMVQLCALYKQAAFSAQKKVLENNGSNGSFLFYFLDALSLPIKLENSLIKEEW
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PURA_DROGR
Sequence: MSTTTIASNAVNGNHYEQLHQGRTKMYKSKVDVVLGAQWGDEGKGKVVDMLASEVDIVCRCQGGNNAGHTVVANGTEFDFHLLPSGVVNEKCISVIGNGVVIHLPSLFDEVLKNEAKGLIHLENRLIISDRAHLVFDFHQHVDGMQEAEKGGKSLGTTKKGIGPAYSSKATRNGIRVGELLGEFNLFSEKFKSIVNTHLRLFPSIKVDIDAELVRYKDYAEKIRPYVKDTICFLHTALRNGKTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNEIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLQYTSLVNGYTCICITKLDILDTLAEIKVGVSYRRSNGDKLDHFPGTISELGGIEVEYAILPGWQTSTEHVRNFKELPENAQSYVRFLESHLSVPVRWVGVGKGRESIINVH
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1884_GEOSL
Sequence: MRVLVITGLSGSGKSTAVRVLEDEGFFCVDNLPVLLFPTIIDLVCRSGENVAGVALVMDIRGRDFIKGFEKVFQQISEAGHTVEVIFFDATDEVLVRRFSETRRRHPALESGSVPEGIRYEREQLAGLRRLATHVIDTSELNVHQLKELVHSRIKGESGTRPLTIHLQSFGYRFGIPLESDIVMDVRFLPNPHFVPELKAGTGLDENVRTYVLEKPETRQFLERFMDLLEFLVPSYQREGKSYLTVSVGCTGGRHRSVAIVEELRAFFAGLGLVVKVSHRDKEKG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein GSU1884.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: Y1776_PSEMY
Sequence: MAANSEPFWKRKTLAQLDRDEWESLCDGCGLCCLQKLEDEDDGAVYYTRIACKLLDLQTCRCSDYANRIKHVPDCIQLTPAQADQFQWLPPTCAYRLVSEGRDLPHWHHLVSGDPDAVHAERISQSGRMLSENSVAEEDWEEHLIFRAG
What are the official names of this protein?
UPF0260 protein Pmen_1776.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: CWP18_PHAVU
Sequence: MGQGAVEGQLFYNVQ
What are the official names of this protein?
30 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HTPX_TROWT
Sequence: MMYSFIARNKINTFLILFVFILACGGFGLLAGRFLGMSFFLFILLLAAGYACVQYFFSGRLAVLMSGARKISRNDNPRLWNTVENLSITTGLPMPEVYIVDDPAPNAFATGRDPKHAKVAATSGLLEILDDSELEGVMAHEMGHVKNYDIRVSTIVFGLVSAVGLISDMVLRALIWGDNRREGNSAFSFVIVLFFSLLAPIAAMLVQLAVSREREYLADATGALTTRYPAALASALAKLEGNARPLQRQSSSMAHLWISNPMPRGFFRKLFSTHPPTEERIRRLKEMGNQF
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL1_MYCBP
Sequence: MSKTSKAYRAAAAKVDRTNLYTPLQAAKLAKETSSTKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADAAVAAGADVVGSDDLIERIQGGWLEFDAAIAAPDQMAKVGRIARVLGPRGLMPNPKTGTVTADVAKAVADIKGGKINFRVDKQANLHFVIGKASFDEKLLAENYGAAIDEVLRLKPSSSKGRYLKKITVSTTTGPGIPVDPSITRNFAGE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CCME_ALBFT
Sequence: MKPRHKRAAIIAGGLAALGIAAYLVLNAFQSNLVFFFSPTQVFAGEAPKNRAFRIGGLVKEGTVKRDNLTVAFVVTDTAKEVPVSYTGILPDLFKEGKGVVAQGKLDENGHFTATEVLAKHDENYMPPEAKAALDQAQIQKTIKSLK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: NDK_SULIN
Sequence: MVMQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDIAEKLYDEHKGKSFFEELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABEC1_MONDO
Sequence: MNSKTGPSVGDATLRRRIKPWEFVAFFNPQELRKETCLLYEIKWGNQNIWRHSNQNTSQHAEINFMEKFTAERHFNSSVRCSITWFLSWSPCWECSKAIRKFLDHYPNVTLAIFISRLYWHMDQQHRQGLKELVHSGVTIQIMSYSEYHYCWRNFVDYPQGEEDYWPKYPYLWIMLYVLELHCIILGLPPCLKISGSHSNQLALFSLDLQDCHYQKIPYNVLVATGLVQPFVTWR
What is the function of this protein?
Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs (PubMed:10373583).  Form complexes with cofactors that confer differential editing activity and selectivity.  Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA.  Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA (By similarity).  May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (By similarity).
What are the official names of this protein?
C->U-editing enzyme APOBEC-1, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1, APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, mRNA(cytosine(6666)) deaminase 1.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_ALBFT
Sequence: MSLTSTDIARIANLARLELKAAESERMLTQINGFFALVEKMRAVDTTGIEPLAHPVATVQDITLRLREDRVSEPNQREANQRNAPALEHGLFLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HSK1_SCHPO
Sequence: MAEAHITLSPKVTHEQQTDIDSECEITEVDDENVNENKSQEMIQDIPARDREEIENITRTFVELQENYRLIEKIGEGTFSSVYKAEDLHYGRYINDWDIQSEVLKESSFGKEKIPVNEDSRKPKYVAIKKIYATSSPARIYNELEILYLLRGSSVIAPLITALRNEDQVLVVLPYYEHTDFRQYYSTFSYRDMSIYFRCLFQAMQQTQTLGIIHRDIKPSNFLFDVRTKHGVLVDFGLAERYDGRQQSHSCRCTNSNAAELAHDFSIAQETSLGYIKNDTRPSKRANRAGTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFLTKRFPMFNSKDDVDALMEIACIFGKSEMRQCAALHGCTFETNVSTLTEKRVNFRKLILWASCGSASIYKEKLRHKPSQEERLCLDFLEKCLELDCNKRISAEEALDHDFLYLDNLAYEKKDDDTAFDNSFGETSFEKDEDLTAKHLSHILDFKEQEETDEPTSLSKRKRSIDEILPNDALQDGA
What is the function of this protein?
Required for G1/S transition.  Plays a role in DNA replication checkpoint signaling through regulating rad3 and cds1.  Involved in the maintenance of mitotic chromosome structures during S phase through regulating the function of rad21.  Required for initiation of mitotic DNA replication through phosphorylating mcm2/cdc19.  Required for genome integrity.
What are the official names of this protein?
Cell cycle serine/threonine-protein kinase hsk1, Cdc7-related kinase, Minichromosome maintenance protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
Protein: MUTH_SHEB5
Sequence: MNRIIPPENLPELLERAHMMAGVSLAQIAAQRGLSVPKDLKRDKGWVGQLIEMELGATAGSKPEQDFLHLGVELKTIPIDSQGRPLETTYVCVAPLSNIQGLTWQNSLVSHKLQRVLWVPVEGERHIPVGERRIGTPILWEPDPQELQLLQQDWEEIMELIALGKVEKLTARHGEVLQLRPKAANSKALTQSIAEDGSLKMTNPRGFYLKTSFTAMILNKVFG
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDA_METVS
Sequence: MNEELQNQFMALDVYNQQVQKLQEELSNIDLMIMELVRAIESMESLKTSGEIMLPLGAGSFVKADVKNPEKIILSVGVDVLLEKDVEEVILDFKNSLDELEKTKELITTQIQKTSKEVTRIRGELEKRAAAIEKQSQTKRGHSGSN
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_DEIGD
Sequence: MIDKQKTIQTYAKSANDTGSTAVQVALLTERINNLSRHLTENKKDKHGQRGLQLLNGQRRRLLKYLERTNYDEYIALTDRLGIRRGQRIVR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: IF2_CORGB
Sequence: MPGKLRVHELAKQLGITSKELLATLKDKGEFVKTASSTIEPPVVKRMQEHYGSSGSDKSDTAAKPAAAKPAAPKPAASAAPKPGAPAKPAAPAAKPAPAAASAAKPGAAPKPGVQAKPAAAAKPGAPAKPAAPSAAKPGSAPKPAAAAKPAFSGPTPGDAAKKAEPAAKPGAEAPRPDGMPRPMGKPAPKPGARAPRVANNPFSTGGGERPAPRPGGGPRPGGGPRPGGGPRPQGQGRPGGQRDGQRDGQRDGQGNRGGQRQGAGAGGPRPQGGPRPQGGSRPQGGSAQGGSAKGAQGAPSQERQGGGRRPSPAMMPPTPGQMPAKAPGKGGRGGQAGGGAGGGFNRGGGTGGGAGRGGRRGGTAGAFGRPGGAPRRGRKSKRQKRNEYESMQAPNVIGGVRLPDGKGATIRLARGASLADFADKIGADAAALVQALFNLGEMVTATASVSDETLQLLGEEMNYKVQVVSPEDEDRELLESFDLQFGEDEGGEADLAKRPPVVTVMGHVDHGKTRLLDTIRKANVGSDEAGGITQGIGAYQVKVNVEDTERTITFLDTPGHEAFTAMRARGAKSTDIAVLVVAADDGVMPQTVEAINHAKAADVPIVVAVNKIDKPEASPEKIRGQLTEYGLIPEEYGGDTIFVDISAKQGLNIDELLASVCLTADAELDLVANPEMDAQGVAIEAHLDRGRGPVATVIVQRGTLRVGDSIVAGDTYGRVRRMVDEYGRDVEEAGPSRPVQVQGLNGVPGAGDNLLVVEDDRIARQIANQRNARKRNALAARSRKRVSLEDLDSVLKEHSTLNLILKGDNAGSVEALEEALLKIEMDDEVQLNIIDRGVGAVTQTNVTLAAASDAVIIAFNVRAEGKATEEANAEGVDVRYYTIIYRAIEEVEAALKGMLKPIYEERVIGHAEIRAIFKASSVGLIAGCMVEDGKVRRNATVRITRDGNVIAENAKIVSLRREKDDATEVSAGYECGMVLSYPDISVDDKIEVYEMVEVPREA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFH47_SCHPO
Sequence: MNENQKSFDSDKSESEDEQKNGRVKVRSRKTDDNEGYTWEGEYQRSWDIVQEDAEGSLVGVIAGLIQSGKRKRLLRDTTPLQRGIIRHMVLVLDLSNSMEERDFHHKRFDLQIKYASEFVLEFFEQNPISQLSIIGVMDGIAHRITDLHGNPQSHIQKLKSLRDCSGNFSLQNALEMARASLSHIASHGTREVLIIFGSILSSDPGDIFKTIDALVHDSIRVRIVGLAAEVAICKEICNKTNSSTKNAYGVVISEQHFRELLLESTIPPATDSAKTTDASLVMMGFPSKVVEQLPSLCACHSIPSRGGFHCPRCKAKVCTLPIECPSCSLVLILSTHLARSYHHLFPLKNWSEIPWSANPKSTHCFACQLPFPKPPVSPFDESTSSMRYACPSCKNHFCLDCDVFAHEQLHECYGCQCSGN
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit ssl1, TFIIH subunit ssl1, RNA polymerase II transcription factor B subunit ssl1, TFB subunit ssl1, Suppressor of stem-loop protein 1 homolog, SSL1 homolog, TFIIH basal transcription factor complex p47 subunit.
What is the protein family that this protein belongs to?
Belongs to the GTF2H2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XKR2_MOUSE
Sequence: MDRVYEIPEEPNVVPISSLEEDVIRGPNPRFTFPFSILFSTFLYCGEAASALYMVRIYRKNNETFWMTYTFSFFMFSSIMVQLTLIFVHRDLAKDRPLSLFMHLILLGPVIRCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIAGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVSLISAEVPLGRAVLMAFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITVWRTLEITSRLVILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVIMVLVFKYFGVKVLLNYCHSLIAVQLIIAYLISIGVMLLFFQYLHPLRSLFTNNVVDYLHCICCRRPRPERVENSETSCEADTTQSIV
What are the official names of this protein?
XK-related protein 2, X Kell blood group-related, X-linked.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NSP3_ROTRH
Sequence: MLKMESTQQMASSIINSSFEAAVVAATSTLELMGIQYDYNEVYTRVKSKFDLVMDDSGVKNNLIGKAITIDQALNGKFSSAIRNRNWMTDSRTVAKLDEDVNKLRIMLSSKGIDQKMRVLNACFSVKRIPGKSSSIVKCTRLMKDKLERGEVEVDDSFVEEKMEVDTIDWKSRYEQLEKRFESLKHRVNEKYNHWVLKARKVNENMNSLQNVISQQQAHINELQMYNNKLERDLQSKIGSVVSSIEWYLRSMELSDDVKSDIEQQLNSIDQLNPVNAIDDFESILRNLISDYDRLFIMFKGLLQQCNYTYTYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: Y2558_SYNAS
Sequence: MEKSFVKRVFAFFLILAAFAFLSLPQAFAEPKGTVVMFHAGSLTMPFEAMEKEFEARYPGVDLQREASGSQAAARKVTDLNKPCDIMASADFKVIDKLLIPKHADWNIRFATNELVLCYTDKSKFAKEVNAKNWYNILQRKGVVWGHSDPNLDPCGYRALMVLQLAEKYYKKPGLYEKILANRPVENIRPKSVELVSLLQTGNMDYAWEYRSVAVQHNLKYVSLPDKINLGNYKEDPYYSQAVVKVTGKKPGEYMEMKGASTTYGITLIKNAPNQEAAVAFLEYMLNPKGGLKILKDQGQPPFIPCRVPTQKMKSTLPEKLQKLVEVKD
What are the official names of this protein?
Uncharacterized solute-binding protein SYNAS_25580.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.
Protein: CYP5F_ARATH
Sequence: MIAVIGLLLGFLVSALFLIQGKRRRTNDNQEKKRSSSEPVEDVVRPKSYSKSEVAVHNKRNDCWIIIKDKVYDITSYVEEHPGGDAILDHAGDDSTDGFFGPQHATRVFDMIEDFYIGELH
What are the official names of this protein?
Cytochrome B5-like protein, AtCb5LP, Cytochrome b5 isoform F, AtCb5-F.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SERPH_HUMAN
Sequence: MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
What is the function of this protein?
Binds specifically to collagen.  Could be involved as a chaperone in the biosynthetic pathway of collagen.
What are the official names of this protein?
Serpin H1, 47 kDa heat shock protein, Arsenic-transactivated protein 3, AsTP3, Cell proliferation-inducing gene 14 protein, Collagen-binding protein, Colligin, Rheumatoid arthritis-related antigen RA-A47.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: SYR_BACVZ
Sequence: MNIAEQMKDVLKEEIKAAVLKAGLADESQIPSVLLETPKEKTHGDYSTNMAMQLARIAKKAPRQIAEEIVASFDKGKASIEKMDIAGPGFINFYMNNSYLTKLIPSVLEAGEHYGETNIGQGEKIQVEFVSANPTGDLHLGHARGAAVGDALCSVLSKAGYDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKKLAEDFGDRFVHEEESERQAFFREYGLKYELDKLRSDLENFRVPFDVWYSETSLYENGKIDQALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGSYTYLLPDIAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYKKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEVGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENKEKSRARLALMKATQITLNNALQLIGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1869_PASMU
Sequence: MMELQDHFLIAMPQMEDDYFAHSVVYICEHNDQGTMGLVLNQPTDLSIAELCAKMNFMMKTDRTYGNDLVLAGGPVNIERGFILHTKTAQTFKHSYKVTDQLSLTTSADIIDTFGTAQAPEKYLVALGCASWTVNQLESEIANNDWLVVPANNRILFDVPYEDRWLEANLLLGIQHHNFAHQAGHC
What are the official names of this protein?
UPF0301 protein PM1869.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: TNFL4_HUMAN
Sequence: MERVQPLEENVGNAARPRFERNKLLLVASVIQGLGLLLCFTYICLHFSALQVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL
What is the function of this protein?
Cytokine that binds to TNFRSF4.  Co-stimulates T-cell proliferation and cytokine production.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: K1B27_MOUSE
Sequence: MRFLILFLALSLGGIDAAPPVQSRIIGGFKCKKNSQPWHVAVLRSNKYICGGVLLDPNWVLTAAHCYGNDTSQHNVWLGKNKLFQREPSAQHRWVSKSFPHPDYNMSLLNDHIPHPEDKSNDLMLLRLSKPADITDAVKPIDLPTEEPKLGSTCLASGWGSITPTKYQIPNDLQCVFIKLLPNENCAKAYVHKVTDVMLCVGETGGGKGTCKGDSGGPLICDGVLHGITSWGSIPCAKPNAPGVFTKLIKFTSWIKDTMAKNP
What is the function of this protein?
Serine protease with chymotrypsin-like cleavage specificity.  Shows activity towards casein, gelatin, IGFBP3 and fibronectin but not towards laminin or collagens I and IV.  Does not hydrolyze kininogin to release Lys-bradykinin.
What are the official names of this protein?
Kallikrein 1-related peptidase b27, Glandular kallikrein K27, mGK-27, Tissue kallikrein 27, mKlk27.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.