PharMolix/UniProtQA huggingface dataset:
Protein: SECA_SORC5
Sequence: MFTWAMKKIFGTSHERAIRRMRPRVEAIGRMEPELQKLSDAQLRAKTAEFKEKLANGATLDDILVPAFAVCREASKRALKMRHYDVQLIGGMVLHNGCIAEMRTGEGKTLVATLPCYLNALEGKGVHVVTVNDYLARRDAEWMGKLYGFLGLSTGVVVNQQGDAEKRHAYRCDITYGQNNEFGFDYLRDNMKFSALEYAQRPLHYAIVDEVDSILIDEARTPLIISGQGERSSDKYRTINEVIPQLRNEEHYALDEKAHSVTLTDEGVETAERLLASLQVLKGTNLYDPVNLETLHILNQCLRAHTLYKRDVNYMVRDGKVLIIDEFTGRVLAGRRWSDGLHQAVEAKENVRIQEESRTMATITFQNLFRLYKKLSGMTGTADTEAAEFHSTYKLDCVIIPTNKPVVRKDYEDLVYKTEKEKFTAVINEILEKHELGQPILVGTTSVEKSTAISRILAKRGVKHNVLNAKHHENEAYVVAQAGRKGAITVSTNMAGRGTDIILGGNAEMLAKLKFKEQNRQPEAEPEAFEALVEEIKKECTAEGDEIREIGGLYILGTERHESRRIDNQLRGRAGRQGDPGTSKFYLSLEDDLMRIFAGDRVKNLMERMGMPDDEPIEHPWVTKSVENAQKKVEERNFDIRKNLLEYDDVMSAQRKTIYDMRQSLLVGRYSPEILDEEGKPTGEKRTIKPLASIVELVRPDVGYLLGMFANDPVMPLDADGNRREIVRKDFEKTERFVELENMQREIYTRWGVKIELETRADKVLEIYDECSELMPLALTEQRERLLDLMDRIIGAMVEESCPARKPPEDWDWGGIFQGFREHFSVELPDDIAHIGDQETLARELYERAEKAYEKREEEIGVELSLRIFRHLYLEELDKAWVDHLTDMDHLRDGIGLRGYGQKDPKQEYKKEGYNMFVNMVARVSSNVVTKLFSVNVRRAEQEEAQIEAADRERHAAALLDAVAQHDESLPLGANPAPARPQPAVMQEQECPCGSGKPFNKCHGGEDEATA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RLME_SHEFN
Sequence: MTTKKRTASSTRWMQEHFDDHYVKLAQKRGLRSRAAFKLEEIQEKDHLIKQGMTVVDLGAAPGGWSQVAAKLTGDKGKVIACDILPMDPIVGVDFLQGDFREDKVLQALLERVGQDKVDVVLSDMAPNMSGSGAVDQPRAMYLVELALDMCHQVLTPNGCFAVKVFQGEGFDDYIKTVKQAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFC_METLZ
Sequence: MYFHALIPFKPVNPKTRLSSVLSQEEREEFARIMLEDVILAVRRTGCSATLLCTSKYECRDALVAIRKEGLNEAINWALPQFHCPALIIMSDLPMVTPGSLQRVISTKADMAIVPGLGGGTNVIFVKKPEKFHVEYYGFSFRRHLQIAEELELTVEIIDSMRMSTDVDEPADLVELMIHGHGNAREWLYEHGFSLSVEDGRVKVHRDGKEVV
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: DHH_PUNTE
Sequence: VMNMWPKVKLRVTEGWDEDGNHFEDSLHYEGRAVDITTSDRDRNKYGMLARLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Desert hedgehog protein, DHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Desert hedgehog protein N- product: Cell membrane; Lipid-anchor; Extracellular side. The N- terminal peptide remains associated with the cell surface. Desert hedgehog protein C-product: Secreted, extracellular space. The C- terminal peptide diffuses from the cell.
Protein: SRP_CHLCV
Sequence: MLTGVENSESGVIDLIKPGLDDVMKNETVQVTLVNSVLGWCKAHIVDPIKTSKIVQSRAFQITMVVLGVILLIAGLALTFVLQGQLGKNAFLFLIPAVIGLVKLLTTSVFMEKPCTPEKWRLCKRLLATTEDILDDGQINQSNTIFTTESSDVTNTATQS
What are the official names of this protein?
Sulfur-rich protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YJL8_YEAST
Sequence: MASCFSVSLLARVAVVEPIRVQLWLNVVNCMIESSMHQCPPRDRHFFSSSRPILLIRRSVSTVYRFVASRTTQVLRAAKTVVKWFIIVDPLINSILINYLIDRLCTLGHAVLRVKKRKTEERQPCSPIIQHTHVKRRKRPRLRIVAIKRKRRRRRPHRIERPLSNMYPIMEIQMVAVPLALPSPTALVHYQQQQQQLPQHHPWYDLSLSEEALSTCCCS
What are the official names of this protein?
Uncharacterized protein YJL118W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EDNRB_RABIT
Sequence: MQPPPSLCGLALLALVLACGMAEVWGEEREMPSAPATPPLLGASEILTPSTKTSWPRDSNASLPRSSAPAEIPKEGRTAGAPRRTPPPCQRPTEIKDTFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVILAVPEAIGFNLVTIDYKGSYLRICLLNPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFGLCWLALHLSRILKLTLYDQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
What is the function of this protein?
Non-specific receptor for endothelin 1, 2, and 3.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Endothelin receptor type B, ET-B, ET-BR, Endothelin receptor non-selective type.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins.
Protein: PROA_THEPX
Sequence: MEVEVKAKQAKAAARRMAVLDENTKNLALNHMADALIKDMGKILEANKKDVVEAEKRNIKASLIDRLKLDEKRVEAMAKGLREISALPDPVGSIEKMWKRPNGLQIGKMRVPIGVIGIIYESRPNVTADAAGLCLKSGNAVILRGGSDAINSNIAISSILAKAAYETGIPEGAIQLIENTDREEVNRMMKLNGLIDLIIPRGGASLIKNVIENSTVPVIETGVGNCHIFVDETAKFNIAKDIIVNAKVQRPGVCNAVETVLVHKSIAKEFLPLMVEELTSLGVEIRGCQITKEICPQVKEATDKDWETEYLDLILAVKVVDGIEEALDHISKYSTGHSESIITENYENAMMFLKSVDSAAVYVNASTRFTDGGEFGFGAEIGISTQKMHARGPMGLEELTTYKYVILGSGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBT3A_ARATH
Sequence: MSKTIILLAFFLSIVLNVQISFVVAESKVYVVYLGEKEHDNPESVTESHHQMLWSLLGSKEAVLDSIVYSYRHGFSGFAAKLTESQAQQISELPEVVQVIPNTLYEMTTTRTWDYLGVSPGNSDSLLQKANMGYNVIVGVIDTGVWPESEMFNDKGYGPIPSRWKGGCESGELFNGSIHCNRKLIGAKYFIDANNAQFGVLNKTENPDYLSPRDFNGHGTHVASTIGGSFLPNVSYLGLGRGTARGGAPGVHIAVYKACWVQRGCSGADVLKAMDEAIHDGVDILSLSLQTSVPLFPETDARELTSVGAFHAVAKGIPVVAAASNAGPTAQTLSNVAPWVLTVAATTQDRSFPTAITLGNNITILGQAIFGGSELGFVGLTYPESPLSGDCEKLSANPKSAMEGKVVLCFAASTPSNAAITAVINAGGLGLIMARNPTHLLRPLRNFPYVSVDFELGTDILFYIRSTRSPIVNIQASRTLFGQSVSTKVATFSSRGPNSVSPAILKPDIAAPGVNILAAISPNSINDGGFAMMSGTSMATPVVSGVVVLLKSLHPDWSPSAIKSAIVTTAWRTDPSGEPIFADGSSRKLADPFDYGGGLINPEKAVKPGLIYDMTTDDYVMYMCSVDYSDISISRVLGKITVCPNPKPSVLDLNLPSITIPNLRGEVTLTRTVTNVGPVNSVYKVVIDPPTGVNVAVTPTELVFDSTTTKRSFTVRVSTTHKVNTGYYFGSLTWTDTLHNVAIPVSVRTQILQRYYDEN
What are the official names of this protein?
Subtilisin-like protease SBT3.10, Subtilase subfamily 3 member 10, AtSBT3.10.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GNTR_BACLI
Sequence: MSQSKNLLYPEKWLSRASTGVRVACELRMRIISGLIESGTILSENKLAAEFSVSRSPIREALKILASEKIIRLERMGAVVIGLTEKEIGEIYDVRLVMETFVFERLGRANVDELVTDLSKILEMMKVSIKYKDADEFSFQDVLFHETIVRSINHSYILMIWNNLKPVMESFILLSMRARLKEKYEDFERILDNHELYIKAIKTKDRDLMLKSLHQNFDDVQGKVEDLWLSQQMLAKGAEQEND
What is the function of this protein?
Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization.  Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone.
What are the official names of this protein?
Gluconate operon transcriptional repressor, P28 protein.
Protein: NORM_BRADU
Sequence: MTMLDTVQHHSQPQSGVPQNHLADEFVETLRLAVPMMLTQLGQIAMITTDLALIGRLGEDAVAAAALAHTVYFVSFTFGLGLMAAVSPLVAQAFGAGDVRRIRRALRVGLWVALLISLPMMASPLYGEHILIALGQVPQSAALAQRYLNGLAWGIAPALGFIALRGMMSAVNRPQPPLWITVAAIPVNAALVYVLIHGLFGLPELGLFGAGLATTLVNLGTFLAVLAIAAWRKPFSDYRPLAHLWRIDWPLVRQLIALGAPISSSLLLEYGLFSSAALLMGLISTTALAAHQIALQVTAVLFMVPLGIGMAATVRVGHAFGRNDPAAVRRAGLVAAVLGVALVSALTVAIILGRYELGRLFFGGSEASAATVELTATLLLVGATFFIADGLQTIMGGALRGINDTRMTLAFAAIGYWCVAFPVAWVLAFHTGLGAVGVWIGFSIGTFVYAGLLVLRFRMLARRLVG
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EMC1_MOUSE
Sequence: MAVAVASGFWIWAAVLLVPAAAVYEDQVGKFDWRQQYVGKIKFASLEFSPGSKKLVVATEKNVIAALNSRTGEILWRHVDKGTAEGAVDAMLVHGQDAITVSNGGRLMRSWETNIGGLNWEITLDTGSFQALGLVGLQESVRYIAVLKKTTLTLHHLSSGHLKWVEHLPESDSILYQMVYSYGSGVVWALGIVPFSHVNIVKFNVEDGEIVQQVRVWTPWLQHLTGACGVVDEAVLVCPDPSSHSLHTLALETEWELRQIPLQSPDLEFGSGFQPQVLPTQPSPVAPSRAQFFLQLSPSHYALLHYHHGAVTLLKNFPQATLVSFATTGEKTVAAVMTCRTEVQKPVSAGDGSVASFPETSGAQDSLACFNQTYTINLYLVETGRRLLDTSISFSLEQKGTRPEQLYIQVFLKKDDSVGYRALVQTQDHLQLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKAAIQDGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVTVTASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKETGMSSLFVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLVDDEYKVTAFPATRNVLRQLHELAPSIFFYLVDAEQGRLSGYQLRKDLTTELSWELTIPPEVQRVVKVKGKRSSEHVHSQGRVMGDRSVLYKSLNPNLLAVVTESTDVHHERTFIGIFLIDGVTGRIIHSSVQKKARGPVHLVHSENWVVYQYWNSKARRNELTALELYEGTEQYNATAFSSLDRPQLPQVLQQSYIFPSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSPDVQVHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDYDYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the EMC1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL15_SALCH
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y624_MYCPU
Sequence: MAGHSKWANIKHRKGAQDAARAKIFQKFAKEIYVAAVAGGPDVDSNPALRLAVNKAKSKSMPKVNIEKAIAKASGNSKSSSTYSEYIYSGTVSKGVQILVICLSDNFNRLSSNIKSYFNKAGGQLSKQGSIPYVYQQKGLIEIDKKLISEDKITEIALEAGAEDIQAEDNYYSITCEPSSFNQVSEFIEKATGFSEFLTREVSYIASDYVELDDESSEKVMAFIEKLENDEDVQAVYHNLG
What are the official names of this protein?
Probable transcriptional regulatory protein MYPU_6240.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_CLOBK
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVKKVEEAYNFLRSVAEEGKDVLFVGTKKQAQEAIEEEAKRSEMHFVNNRWLGGMLTNFTTITARINKLEELDKMEEDGTFEVLPKKEVIKLKNEREKLEKNLGGIRKLDANNVGAMFIVDPRKEKNAILEAKRLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVRLIAAKMADAVLEGRQGEQLAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PA_I59A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYRENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINLNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVGDLKQYDSDEPEPRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNYVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYMRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RIMP_DESOH
Sequence: MGGGNPVVAQMWKLVEPVCSAEGMELVFVEFNKESQGRVLRLYLASGVPDRGVTLEDCAGISRQVNGLLDVYLPELDNYTLEVSSAGLERPLAKEIDFERFAGSRVKIRTAAPVSDRKNFTGILLGVSDGNVRLMVDDKTFVIPYGEITRAKLVNEDGVSQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASB1_ORYSJ
Sequence: MACSHLAAAAAAASPAAARSPAASSAATASAFARLSATPRVASGGLAVRGQRGVAAVVAAAAGAAAATPVADIEERRATEKQPIIVIDNYDSFTYNLCQYMGELGLNFEVYRNDELTIEDVKRKNPRGILISPGPGEPQDSGISLQTVLELGPTIPIFGVCMGLQCIGEAFGGKIIRAPSGVMHGKSSPVRYDEELGKALFNGLPNPFTAARYHSLVIEQETFPHDALEATAWTEDGLIMAARHKKYRHIQGVQFHPESIITPEGKRIILNFVRFIEELEKQRAGEKN
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate.
What are the official names of this protein?
Anthranilate synthase beta subunit 1, chloroplastic, OsASB1, Anthranilate synthase, glutamine amidotransferase component 2-1.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SZRD1_HUMAN
Sequence: MEDEEVAESWEEAADSGEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSLPAGPPPQIRILKRPTSNGVVSSPNSTSRPTLPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDSRQPNNVIRQPLGPDGSQGFKQRR
What are the official names of this protein?
SUZ domain-containing protein 1, Putative MAPK-activating protein PM18/PM20/PM22.
What is the protein family that this protein belongs to?
Belongs to the SZRD1 family.
Protein: MOKE_MONPI
Sequence: MTITFTLPPHQTALTVDEHDKVTIWDVAPCPSLPPDQVCVRVEAVALNPSDTKMRGQFATPYAFLGTDYAGTVVAVGSQVTHIQVGDRVYGAQNEMCPRTPDQGAFSQYTVTRGRIWATVPEGWSFEQAASLPAGISTAGLAMKLLGLPLPDPNATTAPALPKPVYVLVYGGSTATATIVMQMLRLSGYIPIATCSPHNFDLAKKHGAEDVFDYRDAGLAQTIRTYTKNNLRYALDCITNVESTTLCFAAIGRAGGRYVSLNPFPEHAATRKMVTADWTLGPTIFGEGSTWPAPYGRPGSEKDRAFGEELWRVAARLVEDGKIVHHPLRVIPGGFEAIKQGMELVRTGQLSGEKVVVKLG
What is the function of this protein?
Dehydrogenase; part of the gene cluster that mediates the biosynthesis of monakolin K, also known as lovastatin, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:18578535).  Monakolin K biosynthesis is performed in two stages (PubMed:19693441).  The first stage is catalyzed by the nonaketide synthase mokA, which belongs to type I polyketide synthases and catalyzes the iterative nine-step formation of the polyketide (PubMed:18578535, PubMed:19693441).  This PKS stage is completed by the action of dehydrogenase mokE, which catalyzes the NADPH-dependent reduction of the unsaturated tetra-, penta- and heptaketide intermediates that arise during the mokA-mediated biosynthesis of the nonaketide chain and leads to dihydromonacolin L (PubMed:19693441).  Covalently bound dihydromonacolin L is released from mokA by the mokD esterase (By similarity).  Conversion of dihydromonacolin L into monacolin L and then monacolin J is subsequently performed with the participation of molecular oxygen and P450 monoogygenase mokC (PubMed:19693441).  Finally, mokF performs the conversion of monacoline J to monacoline K through the addition of the side-chain diketide moiety (2R)-2-methylbutanoate produced by the diketide synthase mokB (PubMed:19693441).
What are the official names of this protein?
Dehydrogenase mokE, Enoyl reductase, Monacolin K biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: LEXA_SERP5
Sequence: MKALTTRQQEVYDLIRDHISSTGMPPTRAEIAMRLGFRSPNAAEEHLKALARKGVIEIISGASRGIRLLMEDEEGLPLIGRVAAGEPLLAQQHIEGHYKVDPSLFKPSADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIEDEVTVKRLKKHGNVVELLPENSEFQPIVVDLRQQNFTIEGLAVGVIRNGDWV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: WTR42_ARATH
Sequence: MREAGEEKVAWKYFTRDVVPFAAMFAVECATVGSNTLFKAATLRGLSFYVFVFYSYIVSTLLLLPLSVIFGRSRRLPAAKSPLFFKIFLLGLVGFMSQIAGCKGIAYSSPTLASAISNLTPAFTFTLAVIFRMEQVRLRSSATQAKIIGAILSISGALVVVLYKGPQVLASASFTTVLPTVTLHQQLTSIESSWIIGGLLLASQYFLISVWYILQTRVMEVYPEEITVVFFYNLFATLISVPVCLFAESNLTSWVLKPDISLAAIIYSGVFVSLFSALTHTWGLHLKGPVYISLFRPLSIAIAVAMGAIFLGDALHLGSVIGSMILCIGFYTVIWGKAREDTIKTVAGSEQSPLLLTHIIEDGAFPLS
What are the official names of this protein?
WAT1-related protein At5g40240.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFKA_LIGS1
Sequence: MKRIGILTSGGDAAGMNAAVRAIARSAMNAGLEAYGINYGYKGLVEGNIFKMESTKLDEIINRGGTILYSARFPEFAETETQLKGIEQLKKFGIEALVVIGGDGSYHGAEKLTMHGYNSIGVPGTIDNDIPGTDFTIGFDTAANVAMEALDRINDTATSHQRVFVVEVMGRGAGDIALWSGIATGADAIVIPEREYDIEAIANKISENRKNGKDHGLIVLAEGVMGAAEFKEKLDQYGDFDSRAITLGHIQRGGNPTVKDRVLATRLGDYAIRLLLEGKGGLAIGIHDNQLVATDIIDTLENHKHQTDVSLQDLNDRVRF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRM2_MOUSE
Sequence: MVRYRMRSPSEGPHQGPGQDHEREEQGQGQGLSPERVEDYGRTHRGHHHHRHRRCSRKRLHRIHKRRRSCRRRRRHSCRHRRRHRRGCRRSRRRRRCRCRKCRRHHH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-2, Sperm histone P2, Sperm protamine P2.
What is the protein family that this protein belongs to?
Belongs to the protamine P2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS3A1_YEAS2
Sequence: MAVGKNKRLSKGKKGQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVTGFKDEVLETV
What are the official names of this protein?
40S ribosomal protein S1-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: RL30_CORDI
Sequence: MALKITQHKGLVGANPKQRKNMAALGLKHINHSVVHQDTPVVRGMVNVVRHMVSVEEVAGE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CARB_LIGS1
Sequence: MPKRTDVHKIMVIGSGPIIIGQAAEFDYSGTQACLALREEGYEVVLVNSNPATIMTDTEIADKVYIEPLTVESVSRIIRQEFPDAILPTLGGQIGLNLAIALAKTGILEELGIKLLGTQLDAIDQAEDRQRFKDLMQELNEPVPDSKTVETVQEALDFAAEIGYPVIVRPAFTMGGTGGGLCDNPEQLKEIVANGLELSPATQCLIEKSIMGYKEIEFEVMRDADNNAMVVCSMENFDPVGIHTGDSIVFAPTQTLSDREYQMLRNCSLKLIRALKIEGGCNVQLALDPNSYRYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIKNPVTGTTFAEFEPALDYVVAKIPRWPFDKFTRANRRLGTQMKATGEVMAIGRSAQEALQKAVRSLEIDEKDLISAKAQSATDDEVEEKLFHAQDDRLFYIAEAFRRGYTIEEVHELTKINLYYLDIVKQIVELESELSQNKEDLDVLKRAKRYGYSDYTIAKLWGTTEDEVRNLRKEHKLLPVYKMVDTCAAEFDSSTPYFYSSYDLENESKKSDKKSVLVIGSGPIRIGQGVEFDYATVHSVKAIQKLGYEAIVMNSNPETVSTDFSISDKLYFEPLTLEDVLNVIDLEQPMGVIVQFGGQTAINLAAGLEAHSVKILGTTVEDLDRAEDRELFDQTIKNLGLKQPIGKTATTQEQVIACAEEIGYPVLVRPSYVLGGRAMEIVNNEQELLDYLAQNAPAEIDHPILVDAYLSGLECEVDAICDGKDVLLPGIMEHIEHAGVHSGDSMAVYPPQSFDENIKQQIVDATEKLAVALKCVGIMNIQFIIHNNEAYVLEVNPRASRTVPFLSKITGIEMAQVATRVILGESLAEQGYQSGLYRESDMVHVKAPVFSFSKLADVDSFLGPEMKSTGEVMGSDYTFEKALYKAFTGAKMELPDNGNVLLTIEDKDKDAVLPLAKRFSKIGYRMFATEGTSQFLRENGLFVQTVDKLGKDTGNETSLHDLIVNDGVDLVINTMSHDQEVASDGFVIRQLAIEHNIALLTSLNTADALLKALENRSFATNSL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.