PharMolix/UniProtQA huggingface dataset:
Protein: RAN_SALSA
Sequence: MAEGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGAIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEILMDPSLAAQYEHDLKVASETALPDEDDDL
What is the function of this protein?
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs.  Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis.  Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way.  Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport.  Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins.  RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.  Required for normal progress through mitosis.
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Cytoplasm, cytosol. Cytoplasm. Note=Predominantly nuclear during interphase. Becomes dispersed throughout the cytoplasm during mitosis (By similarity).
Protein: SECA_THEM4
Sequence: MKLFDKNERVLKRYWKRVKKINEINLSNVPFSELILNMEKIKNNITGENIDDYLVDVFAIVREIAKRTIGLRPFDVQLIGGMVLHEGKVAEMKTGEGKTLVATMPIVLNALLKKGVHLVTVNDYLAKRDAMWMGPIYLALGLRVAVINTQNKSYEVVWKNKELFEKAIRENLSVWPEGFAEEFLPDDKKVNTDCFDVELKEITRKEAYECDITYGTNTEFGFDYLRDNLVINLDSRVQRGHFFAIVDEVDSILIDEARTPLVISGPSKTKASDYRRFNQVAKRLKKDVHFTVDEKKKTVVLTDEGIEYVEKLLNIENLYDPEHVNKMYFLLNALKAHHLFKKDVDYIVNNGEVIIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPIKEESLTYATITYQNYFRMYKKLAGMTGTAKTEEEEFKQIYGMEVVVIPTHKPMIRKDRDDLIYRTEEEKFQAVVSEIKKRHEKGQPVLVGTTSIEKSERLSQMLKKENIPHNVLNAKYHEKEAEIVARAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLLIIGTERHESRRIDNQLRGRAGRQGDPGESIFFLSLEDDIIRIFGGEKLEKIMNLVKIEKGEPIYHPMLTKLIERVQKKVESINFAIRKNLLQMDTVLDAQRKAIYSYREYLLSGNLDEHFYDAMEDFIERILEEFCEKEVCDTQKINESLKILNIDEKLPDTREETKKYLKDIILKRYNKKKEELGEDFSKIGKYIALRVLDENWRQYLEEVEHVKEAVSLRAYGQKDPIIEFKKETFRMFDEMMARIYEQSIVYTLNIRKITDEAEKESKKELEKLYVQHDEFSLVNRKERRTAEKKGKKRLKVKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: YPEA_ECOLI
Sequence: MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSLFLVAEVNGDVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY
What are the official names of this protein?
Acetyltransferase YpeA.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: RS11_CENSY
Sequence: MSGTEAGAGEPAAEEPTKEAAQPEAGAPDAGTPEASAPEAGAAQPEAGTQPEAGTAQPEAPPEGTPETTPADEKLGIAHIYSSYNNTIIHMTDLTGAETVSISSGGVHVNADRYESSPFAAMKAANKVIESARAKGFTGFHIRVRAVGGVGSRVPGPGAQAAIRALARGGFRIGRIDDVTPIPHDTTRKKGGKRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MRAY_BORT9
Sequence: MFCLLGLRLLKYITFRTAYATIFAFLLALIFGPFIILRLKKLKLDQILRKDGPKRHLSEKIGIPTMGGILIFFCVLVSLFFWIDFWNIYFLIILFVMVSFACLGFMDDLLKIKRKNSDGLNPRFKIYGQILFSCISVTMLYYFGDEHVSIIYFPFFKSLKLDLGVLYIPFGMFILISASNSFNLTDGLDGLAIGLSIVVTGALVIIAYLASRVDFAFYLNIPNIKGAEELVVFLGALLGGSFGFLWFNAYPAKIMMGDTGSLSIGAVLGMTALILKSEILFAILAGVFVVETLSVIIQVVVYKHTKKRVFKMAPLHHHFEELGWSEMQVVIRFWIIGLIFAIIALSTLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL4_ALIFM
Sequence: MELMVKGADALTVSETTFGREFNEALVHQVVVAYAAGARQGTRAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIWRTGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVDNFSVEAPKTKELVAKLKELELNDVLIVTGEVDENLFLAARNLYKVDARDVAGIDPVSLVAFDKVLMTAAAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: URE3_KLEAE
Sequence: MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_PROM0
Sequence: MNLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELNSASIIAKHFDIEEFKIIKLDLSLWGGSSLTDSQKNIPIEGVQANKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLAFDNHVPFDKTWSCYSGNSKPCGKCDSCRIRNAAYEKWLNNKNKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RPOC_UREP2
Sequence: MSQKGIKSLTISIASPEQILNWSKGEITKPETINYKSLKPEPNGLFDESIFGPSKDYECYCGKYRKVKHKGKICERCHVEITESIVRRERMGHIELAAPVAHIWFTKELPSPSKISLLLDITYKEVDQVVYFVNYIVLDEGNNVYDGKSIFNKKEVLDLTSPKNSIRSRNKLRRTLRNIQERIEDELNHEREALIQDFDYRLAVTYDQMLKDSNIPFSVKDVMAFIEKHTGVRFGIGAEAIRELLEKLNLEEEHEKIKQAIQNSPNAYDQKTKRLLRRLECVRWIKDSGSKPEWMVMTRIPVTPSETRPIISLDGGRFTTSDTNNFYRKIIIRNERLKQMQATDAPEILLDNEKRLLQEAVDSLFDNNSRKKPVVGKDKRPLKSLSNHLKGKQGLFRQNLLGKRVDYSGRSVIVVGPELKMYEVGIPALMILKLFRPYIISELIRKRDELGNEIQPICANIKLAEQKILAQDNEIWPVVEKVIKQRPVILNRAPTLHRLGIQAFEPKMVDGKAIRLHPLVTTAFNADFDGDQMAVHIPLSKEAVAEARSILLASWHILGPKDGKPIITPTQDMILGIYYLTKEKFPQVIEEMMAKDPTQARVEFINNFHIFSTQDEAIRAYKLKTIRINDVIGITTKAFNNKTFSKEGILVTTVGKIIFNQAFPVNFPYINDVKNLYGENQFEIIGMHESILDYLKAYNLKEPLTKKTLSTVIDYLYKVSEIEVVPQTMDKIKALGFKYSMISATSISAFDIPSYDQKYEYFKETDELVSKLREFYLDGKLTDDERYTKVVQAWSQTKDKVTHDIEKLINSNEYKDNPIVIMAKSGARGNTSNFTQLAGMRGLMSKSYNYDQKNNNGVIKDTIEIPIKHSFIEGLSVSEYFNSSFGARKGMTDTAMKTAKSGYMTRKLVDSTQAVVIKDHDCGTKEGIIVREIRNTKDNTSIESLKDRIVGRYSINTIYDTKNKLIIESDKLITSEIANIIQNSGIREVEVRSPLHCASLYGVCQKCFGLDLSTNKLIETGTAIGVIAAQSIGEPGTQLTMRTFHTGGVAGDTNITQGFERIKQLFDCIQPQENEKAVISQVKGTVERIEKDSNTNGYNVVIKYNKDNYVNYPTRSNAVLRVKTGDEIIAGQKITEGSIDVNDLLKYAGIENVRHYIIKEVQKVYRMQGIEISDKYIEVIISQLTNKITITNPGDSGLFVGETISINEFTEVAQNMLVNKKKPPSAINQVFGLDHAPSKSGSFLSAASFQDTKKILTDAAARSQKDMLIGLKENVILGNLIPAGTGLKDVEEVIAYGEEMYKKQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CSPLO_MAIZE
Sequence: MFASRPVVHPLEVAAPAHPVQQPAPGVLMKDLPGMPGTPGGLGLRVLQLLFAAISLAVMSSTADFASVSAFCYLITTTVLQCVWSLTVAIVDIYALLVKRCLQNRRAVTLFSIGDGITWLVSFSGACAAAGIPVLIDADLIMCSENPCASFQTAVAMGFMCCFSLLPSFLLNFYSIASSHG
What are the official names of this protein?
CASP-like protein 5A1, ZmCASPL5A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M2_I00A1
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGIVHLILWIIDRLFSKSIYRIFKHGLKRGPSTEGVPESMREEYREEQQNAVDADDGHFVSIEL
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: ARI2_HUMAN
Sequence: MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAEQRRRTLLKDFHDT
What is the function of this protein?
E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655).  Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity).  The initial ubiquitin is then elongated (By similarity).  E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655).  Mediates 'Lys-6', 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006).  May play a role in myelopoiesis (PubMed:19340006).
What are the official names of this protein?
E3 ubiquitin-protein ligase ARIH2, ARI-2, Protein ariadne-2 homolog, RING-type E3 ubiquitin transferase ARIH2, Triad1 protein.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: OST48_RAT
Sequence: MKMVPRLAVRAWPLCGLLLAALGCVCASGPRTLVLLDNLNVRDTHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGRNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGAQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIEQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMAGLFLFSVVFLHMKEKEKSD
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ZN750_HUMAN
Sequence: MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCPKSNSLDPKQTNQPDATAKPASSKSVANGLSAFDSKLQHSSAREDIKENLELQARGTHRCLGQKPALHRASPCKSPAPEAALGAQPALEGAARPSAFVPVGEHRLKGPDNAEAPETLALHNPTAKAVSFHTKSAFHTPGYPWKAGSPFLPPEFPHKISSTKGLGAISPYMHPTIPEYPPHFYTEHGLATIYSPYLLAGSSPECDAPLLSVYGTQDPRHFLPHPGPIPKHLAPSPATYDHYRFFQQYPSNLPIPYGFYRPESAFSSYGLRLPPVTGLTRDQSSHLLEEATLVYPASSPSRLNPSDPNRKHVEFESPIPEAKDSSKAGQRDTEGSKMSPRAGSAATGSPGRPSPTDFMQTSQTCEGLYDLSNKAASSALGRLYPPEQSLTAFRPVKKSTECLPAQAAETTAESPVSLNVVNGDPPAPTGSASLVSEAAPSSPDDSSGMGPLNLSKKSEINLAATHEPTYQGSPQAETASFSELQDLPLNLSVKDPCNTQAPRPAFPGRPRAAEPAAAVPQKTGTEGSEDGPSHPETKPGSLDGDGAPPTGPGEEAPDACAVDSSEEQKQTAAVALCQLAAYSPRNIRVGDGDAAAPEPACRQDTPTLSSMESQEAQCDLRPKGQKRTSLRDAGKSQQGAKKAKLQDTARVFTLRRRARVS
What is the function of this protein?
Transcription factor involved in epidermis differentiation.  Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes.  Specifically binds to the promoter of KLF4 and promotes its expression.
What are the official names of this protein?
Zinc finger protein 750.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSB2_PYRHO
Sequence: MLQLTEKFKGTTTVGIVCKDGVVLAADRRASLGNIIYARNVTKIHKIDEHLAIAGAGDVGDILNLVRLLRAEAKLYYSQSGKRMSVKALATLLANIMNGAKYFPYLAWFLVGGYDEKPKLYSVDMVGGITEDKYATAGSGMEFAYSILDSEYKDNLTLEEGIKLAVKAINTAIKRDVFSGDGILVVTITKEGYKELSDSELEATLKQ
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_CAVPO
Sequence: GIVEGLMTTVHAITATQKTVDGPSGKLWRDGRAAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGSLKGILGYTEDQVVSCDFNSDTH
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Modulates the organization and assembly of the cytoskeleton.  Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks.
Protein: RPOC_XANCB
Sequence: MKDLLNLFNQQRQTLDFDAIKIALASPDLIRSWSYGEVKKPETINYRTFKPERDGLFCAAIFGPIKDYECLCGKYKRMKHRGVVCEKCGTEVTLAKVRRERMGHIDLASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFEAYVVTEPGLTPLERRQLLTEEQYLTARQEYNDDFDAAMGAEAVYELLRTIDLQSEMTRLREEIASTGSETKLKRLTKRIKLIEAFLESGNRPEWMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLRRLLELNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLKLHQCGLPKKMALELFKPFVFAKLQRRGLATTIKAAKKLVEREEAEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMSRALENKKGEGMVFANTSEVKRAYDNRVVELHAKVKVRITQVDVDTVDGKRTSGTSIVDTTVGRALLSEILPEGLPFQLANTEMTKKNISRLINSSYRLLGLKDTVVFADKLMYTGYAYATRAGVSIGIDDMLIPDEKKGILTEAEAEVLEIQEQYQSGLVTAGERYNKVVDIWSRTSGRIAKAMMDTIGTEKVENAKGETIDQKSMNSLYIMADSGARGSQAQIRQLAGMRGLMARPDGSIIETPIKANFREGLNVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITEVDCGTTEGLIMTPIVEGGDVVEPLKERVLGRVVAEDVYLPGNDEEPIVTRNTLLDEAWVAKLEDASVQSVKVRSTISCESSFGVCARCYGRDLARGHQVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAVDNITVKTTGSVKFNNLKSVAHASGALVAVSRSGELSVLDGHGRERERYKLPYGATITAKDGDAVKAGQAVANWDPHNHPIVSEVAGFIRFIDFVDGVTVIEKTDELTGLASREITDPKRRGAQAKELRPIVRIVDAKGNDLTIPNTDLPAQYLLPPRSIVNLQDGAAVGVGDVVAKIPQEASKTRDITGGLPRVADLFEARKPKDPAILAERSGIISFGKDTKGKQRLIIKDTDGSEHEELIPKYRQIIVFEGEHVTKGETVVDGEPSPQDILRLLGVEPLAAYLVKEIQDVYRLQGVKINDKHIEVITRQMLRKVEITDQGNSKFLNGEQVERQRVIEENARLVTRNELPAKYDPVLLGITKASLATESFISAASFQETTRVLTEAAVRGTRDNLRGLKENVIVGRLIPAGTGLAYHAGRRKASGLTDSEMETLSGKPAVAEPVATVADAGADEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: LEXA_RALPJ
Sequence: MATLTPRQQQIYDLIRQTIQRTGFPPTRAEIAAEFGFSSPNAAEEHLRALARKGVIELTPGASRGIRLRAAGDTAQHQFSLPSMGLMQLTLPLVGRVAAGSPILAAEHIDRQYQVDPSLFSAQPDFLLKVRGMSMRDAGILDGDLLAVQRASEATNGKIVVARLGDDVTVKRFQRKGRHVELIAENPDFEPIHVDLDRDEFHLEGLAVGLIRPAAP
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GLPK_OCEIH
Sequence: MSEKFILSIDQGTTSSRAILFNHKGEIVESAQKEFEQFFPKPGWVEHDANEIWTSVLACIADVLRKADIEANQIEGIGITNQRETTVVWDKNTGRPIYKAIVWQSRQTEGICKELKEQGHEDTIRHKTGLLIDPYFSGTKVKWILDNVDGAREKAEAGELSFGTIDSWLIYRLSGGKTHVTDYSNASRTLMFNIYDLKWDDELLEILDVPKSMLPEVKPSSEVYANTVSYHFFGEEVPIAGVAGDQQAALFGQACFDQGMAKNTYGTGCFLLMNTGEEPVRSKHGLLTTIAWGVDGKVEYALEGSIFVAGSAIQWLRDGLRLIESSPQSEALASQVETTDGVYLVPAFVGLGTPYWDSDARGAVFGLTRGTTKEHFVRATLESLAYQTKDVMDAMLADSDIDLKKLRVDGGAVKNNLLMQFQSDILGVTVERPVVQETTALGSAYLAGLAVGFWKDKEEIAKQWLNEKTFENEMSEEESSYLYKGWQKAVEATRSFKFES
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MTAD_DESVM
Sequence: MTRPCDILIQAACIVTQDAMRTVVEDGALAVADGTVLAVGPREAVTAAHAPARLLDLGNALVMPGLVNAHTHAAMTFLRGVADDLPLMDWLTQHIFPVEKHLTPDIVEAGALLGCAEMLRTGTTAFNDMYLIQDATYRAVDTAGLRCLGGEGIFGFPSPAYPDADAGLDLVRRLHETWRHNPRIRQCVTPHAVYTTSPELLQRCQALAEELDLPLHIHLAETTTETAQCQQMFGQRPVPYCHGLGLLTPRATVAHAVDLTDDEMDLLASTGAAVAHNPESNMKLASGAAPVPQMLARGIAVGIGTDGAASNNSLNMFTEMTSCAMLHKLRCMDPTCAPAQTVLDMATLGGAAALHWPGLGQLAPGCPADLTVLDLSAPNLQPMYNPASHLVYAATGHEVRLTMVAGEVLYQDGRFTRFDYPALMAQMRDVRRWVLDKLGR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: SURE_BURM9
Sequence: MRILLSNDDGYLAPGLAALYEALRPLAEILVMAPEQNCSGASNSLTLSRPLSVSRSAATGFYYVNGTPTDSVHVALTGMLDTKPDLVVSGINNGQNMGDDTLYSGTVAAATEGIMFGVPAIAFSLVHKEWAHLGDAARVAAEIVRHYLDHPLPGQPLLNVNIPNLPYEELKGWRVTRLGKRHPSQPVIRQTNPRGEPIYWIGAAGDALDASEGTDFHATASGYVSITPLQLDLTHTQMLGATRDWARAGSGAS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_GEOSL
Sequence: MDIFSEKRILTVSQLTSLIRGVLEENFEHVWVEGEVSNLATPASGHLYFTLKDGAAQIRCVMFRASSRALKFRPRDGMGLIVRGRVTVYDQRGEYQLLVEYLEPRGIGALQLAFIQLKEQLAREGLFADEHKKPIPPLPQKIGVVTSATGAAIHDILTVLNRRFANVEILIRPVKVQGEGAAEEIAAAIDDFNRYGVIDVMIVGRGGGSLEDLWAFNEEMVARAIHRSRIPVISAVGHEVDFTIADFVADLRAPTPSAAAELVVKSKEELAARLEFLRHRLVQGGRQVLAERRGELDSLNRSLRDPSMLVGHLSQRVDDLSARLERGTANSVRRHRGSLDLLTTNLRLTNPAVRLERARERVIALAGRNETLLRRFLDHLREKTLVAAARLDTLSPLATMARGYSIVLKLPERCLVTDSARLAPGDRVELCLRRGRAGCCVESSSDT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.