PharMolix/UniProtQA huggingface dataset:
Protein: MOB2_DICDI
Sequence: MTLFSSLLSRVSKDGKESIRGNYKPKKHPRGSSRHTMRKSLKKNLAGGTVLKESVKCPDGEDENEWIAVNTIEIFNTMNMCYSFIQGFCTEASCPQMTGAKATYLWTDGKGKPQELSAPQYIDNLVNWISEQIDNPEIFPVDDSDFPKNYRPAVIKIISRVLRVYAHIYHAHWDHIQKLDCYQHTNTSLKHLQYFAEHFSLIGEKDLAVMKHVFDTL
What are the official names of this protein?
MOB kinase activator-like 2, Mob2 homolog, Mps one binder kinase activator-like 2.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
Protein: SSRP_PSESM
Sequence: MAKLKKHPTGTIAQNKKARHDYFIEHKFEAGLVLSGWEVKSLRATKVQLVDSYVLLKDGEAWLMGCHITPLKTASTHVIADPTRTRKLLLNQRELEKLTSSVQQKGYACVALSIYWKQHLIKCEIALGKGKKEYDKRHTERERDSDRELQRAVRTKGKDD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AFTR1_ALTAL
Sequence: MMLQCAPKKNERLRGSCDFCTQSKLRCNKNKPSCRRCTLQQQPCVYSVARRTGRPPKHPRKANDCQEANGQHGDQDPVTSTPGGSYQQQSNHLLDVEGDGANFTLADASTTAQGRETAASPALDNALLVGETFGFSSLLDDPLIQSDDFFSFSLCMPPGEKEGHMASPRTLNGSTGPCSPTVLSSIDVPHLPGRFGFLESSVESGLHGRTRPHLVEQPDKTVPSSFSEIEKIYDEGLTFSGLDSAINAVTNNGKGEPNISGTMAAHPHSKRQCFCSTSMSKLQMLVLHPTLCQKNSRARFDMALFLEEVVFSIYRDVLQCLVCQSKSLHSLASLCICTDWVIEALRDVAQDLSSGQDNLGGFRAGLYPPKDKFSICVGRFVLDDQLRESCTRSLVRYRLRKLIPIMDTMMKLNHRGAGGALSQAIRTMVEDVHHKIESALGMMEL
What is the function of this protein?
Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (Probable).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).
What are the official names of this protein?
Transcription activator AFTR-1, ACT-toxin biosynthesis regulator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: P2RX4_MOUSE
Sequence: MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ
What is the function of this protein?
Receptor for extracellularly released ATP acting as a ligand-gated ion channel that plays multiple role in immunity and central nervous system physiology (PubMed:26456657, PubMed:35119925).  Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation (PubMed:35119925).  Participates also in basal T-cell activity without TCR/CD3 stimulation (PubMed:35119925).  Promotes the differentiation and activation of Th17 cells via expression of retinoic acid-related orphan receptor C/RORC (By similarity).  Upon activation, drives microglia motility via the PI3K/Akt pathway (PubMed:17299767).
What are the official names of this protein?
P2X purinoceptor 4, P2X4, ATP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: SVKA_DICDI
Sequence: MASKKGDPEELYVRQEKIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGSFLKGSKLWIIMEYLAGGSVLDLMKPGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLSASGDVKLADFGVSGQLTDQMTKRNTFVGTPFWMAPEVIKQTGYDSKADIWSMGITALEMAKGEPPRADLHPMRALFLIPKDPPPTLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKFIKAAKKTSSLTDLIERRQKWLQLNGNNADDENDDLDRDAKSNEEDFGWEFPTIKQKSPVAVQEQQQTPQKPTVVSTPIKEQQQQQQPTPVTTPQQPVTTTTTTPTTETKVRSLSNSSQTTPVKTTVAATTAPATTPASNAPTSTTPNGAAVTQQQAPRASALTSVIYPVLSKLLKNTSDENVINALAQLKMAFDNAEKAKPGITHSLIAQIIETLKR
What is the function of this protein?
Involved in regulation of actin cytoskeleton organization during cell motility; F-actin fragmenting and capping protein allowing dynamic rearrangements of the actin cytoskeleton.  Also part of a regulatory pathway from the centrosome to the midzone, thus regulating the completion of cell division.
What are the official names of this protein?
Serine/threonine-protein kinase svkA, Severin kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Note=Shows overall localization in the cytosol and, to a lesser extent, in the nucleus. Enriched around the centrosome. In dividing cells, forms a cloud around the spindle and nuclei. Enriched in the cleavage furrow during late cytokinesis.
Protein: P19_HARV
Sequence: MEGAIQGSDAREQANSERWDGGCGGTITPFKLPDESPGLHEWRLHNSEESEDKDHPLGFKESWGFGKVVFKRYLRYDGTEASLHRALGSWERGSVNDAASRFLGLGQVGCTYSIRFRGSCLTLSGGSRTLQRLIEMAIRTKRTMLQLTPSEVEGNVSRGRPEGAKAFEKESE
What is the function of this protein?
Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs).  Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
What are the official names of this protein?
RNA silencing suppressor p19, 19 kDa symptom severity modulator.
What is the protein family that this protein belongs to?
Belongs to the tombusvirus protein p19 family.
Protein: GCSH_XYLFA
Sequence: MSDIPGDLKFLKSHEWVRIEDNNRAIVGISDHAQNLLGDLVYVELPNIGDHLDAGTTAAVIESVKAASDIYSPVTGKVIEVNTTLSDKPETINEDPYGEGWIMVIEMQAPEEISDLLSPDDYTKVLESDEH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CMR1_ASPOR
Sequence: MGNEEISDFEKQRLANIAERDALLKQLSLNAQSVFTPTLPNRATGSQAKTKKKPAPKKVKKEEESPAPRRMSSRLRGIAADSEVAKRKAEEQHQAYQEAERAKRVRKSDSFSLNDIFVSGQKLSGDGLLGVDVVTKGVAVPYQRTFGDDDIKKTTDKELKALRKEMSELQLWEAWEPNRIKLTPERVYTMTFHPSETKPLIFAGDKMGHLGILDASQEKPTSVKQEDEDEEDDDPDPVLTTLKPHTRTISSMVIHPSKPTHLYTASYDSSIREMDLDKTTSVERYAPDSTSDDVPLSGLDMAADDPNTLYWTTLEGEFGRYDMRTPKQGSVAVWSLSEKKIGGFSLFPTHSHYFATASLDRTMRLWDIRKLSRREPVPVGEHQSRLSVSHAAFNSAGQVATSSYDDSLKLYDFGAKGIASWKPGHTLSDAEMKPDTVVRHNCQTGRWVTILRPQWQINPQSHIQRFCIGNMNRFVDVYSSSGDQLAQLGGDGITAVPAVAVFHRSKNWIAGGTASGKICLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein cmr1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: PYRF_MYCUA
Sequence: MTGFGARLAEAKAHRGPLCLGIDPHPELLRAWDLPATADGLAAFCDICVAAFAGFAVVKPQVAFFEAYGAAGFAVLEGTMAALRANGVLVLADAKRGDIGSTMAAYAAAWAGDSPLAADAVTVSPFLGFGSLRPLLEVATANDRGVFVLAATSNPEGATIQRADADGRTVAQLIVDQVGLFNSEVGEVTGSEPGSVGVVVGATVLNPPDVSGLGGPVLVPGVGVQGGRPEALGGLGGAAPQQLLPAVSREVLRAGPSISEVRAAAERMLDSVAYLSAV
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: PURA_LISMH
Sequence: MSSVVVVGTQWGDEGKGKITDFLSENAEAIARYQGGNNAGHTIKFDGVTYKLHLIPSGIFYKEKISVIGNGMVVDPKALVEELKYLHDKGVDTSNLRISNRAHIILPYHIRIDEADEERKGANKIGTTKKGIGPAYMDKAARVGIRIIDLLDKETFKEKLEHNLGEKNRLLERFYELEGFKLEDILEEYYDYGQQFKEYVCDTSVVLNDALDDGKRVLFEGAQGVMLDIDQGTYPFVTSSNPIAGGVTIGSGVGPSKINHVVGVAKAYTTRVGDGPFPTELFDSIGDTIREVGHEYGTTTGRPRRVGWFDSVVVRHARRVSGLTDLSLTLLDVLTGIETLKICVAYKLDGKTITEFPASLKDLARCEPVYEELPGWTEDITGVTSLDDLPVNCRHYMERIAQLTGVQVSMFSVGPDRAQTHVIKSVWRLA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSL_DANRE
Sequence: MAAAQISAEEMEELREAFTKVDVDGNGHISTDELNALFKAANLPLPGYRVREIIQEISRTMDLNQDGKITFDEFAKVVHDLKSSEVAKTFRKAINKKEGICSVAGTSEQSGTQHSYSEEEKVAFVNWVNKALEKDPDCQHVLPMDPSTDDLFTAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGRQHLVLGLLWQVIKIGLFADIEISRNEALIALLRDGESLEDLVKLSPEELLLRWANYHLEEAGCPKINNFSSDIKDSKAYYNILNQVAPKRDEEGIPAIPIDISGIREKDDLKRAECMLEQADRLGCRQFVTATDVVRGNPKLNLAYVANLFNKYPALKKPENQDIDWSSIEGETREERTFRNWMNSLGVNPRVNHLYVDLADALVIFQLYEKIKVPVDWDKVNKPPYPKLGSNMKKLENCNYAVELGKKEAKFSLVGIAGQDLNEGNRTLTLALLWQLMRRYTLNILEDLGDGQKIIDETIVQWVNETLTQAGKGTISGFKDGSISSSMPVLDLIDAIQPGSIRYDLLKAEDLTDEKKLNNAKYAISMARKIGARVYALPEDLVEVKPKMVMTVFACLMARGMRRI
What is the function of this protein?
Actin-binding protein.  Plays a role in the activation of T-cells (By similarity).
What are the official names of this protein?
Plastin-2, L-plastin, Lymphocyte cytosolic plastin 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SURA_BURL3
Sequence: MKKTLRFAAVVSSLAAASALLAAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRAGLIARRLQQQNAPVPPTDQLRAQVLNQMVLERIQVQKAKDDGIRIDDATVQSTLQRLAQANGMTLEQYRGRLEAQGVPWSVFTSDARTELMLSKLREREVDGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFEKLAKNNSEANDAKKGGDLGFKAPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGATAAAPKIVQTHVRHILLRVGEGKSEGQARQQLADIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLSRREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: PHS_YEAST
Sequence: MHNKIVRIASSALTGGKLLEKLKPLTRWEVQWDPNKTKCLGITREVTFKDYETTWAFLTRVSMRSHLWGHHPLIHTSYTWVKLELHTHDIDPKDGAHSQLSDIDVRMAKRIDSYIDEMTT
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: GCSPB_THEAB
Sequence: MTIFEISKEGRIGFQLPDNNIKDYEINLPEHLLRKSLPRLPQVSEVDVVRHYTNLSAKNYSVDVGFYPLGSCTMKYNPKVNEKVASFEEFSMIHPFQPHETVQGALKLMYDLKEMLCEITGMDDMTLIPSAGAHGELTGILISRAYHLSRGDTKRTKVIVPDSAHGTNPASARMAGFDVIEIKSGPDGRVDLNELEKVLDETVAVIMLTNPNTLGLFEKDILKIAQMAHDKGALLYYDGANLNAILGRTRPGDMGFDIVHLNLHKTFSTPHGMGGPGSGPVGVKKHLAKFLPVPEIVKIEDKYTLNYNKPESIGFIRSYFGNFSVMVRAYTYIKTMGKDGLKKAGEMAVLNANYLRVKVSKIMDIAYPGICMHEFVSTCEKLTKETGVKALDIAKRLLDYGIHAPTMYFPLIVHEDFMIEPTETESKDTLDKFAQILEKIFNEARENPELVKGAPYNTPVRRLDDVSASRKPVFKYNFEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: SP3AB_BACSU
Sequence: MLKLLGAVFIVVATTWTGFEMAKIYTERPRQIRQLRAALQSLEAEIMYGHTPLHTASQQIAKQLAQPVSTLFSAFSDQLDKGSDSAKTAWEQSLKKVWDTLSLKKSEYEVLKQFGETLGIHDRISQQKHIKLALTHLEASEADAEQAQAKNEKMIKSLGFLAGLLLILLLM
What are the official names of this protein?
Stage III sporulation protein AB.
Protein: ANGR_VIBAN
Sequence: MNQNEHPFAFPETKLPLTSNQNWQLSTQRQRTEKKSITNFTYQEFDYENISRDTLERCLTTIIKHHPIFGAKLSDDFYLHFPSKTHIETFAVNDLSNALKQDIDKQLADTRSAVTKSRSQAIISIMFSILPKNIIRLHVRFNSVVVDNPSVTLFFEQLTQLLSGSPLSFLNQEQTISAYNHKVNNELLSVDLESARWNEYILTLPSSANLPTICEPEKLDETDITRRCITLSQRKWQQLVTVSKKHNVTPEITLASIFSTVLSLWGNQKYLMMRFDITKINDYTGIIGQFTEPLLVGMSGFEQSFLSLVKNNQKKFEEAYHYDVKVPVFQCVNKLSNISDSHRYPANITFSSELLNTNHSKKAVWGCRQSANTWLSLHAVIEQEQLVLQWDSQDAIFPKDMIKDMLHSYTDLLDLLSQKDVNWAQPLPTLLPKHQESIRNKINQQGDLELTKELLHQRFFKNVESTPNALAIIHGQESLDYITLASYAKSCAGALTEAGVKSGDRVAVTMNKGIGQIVAVLGILYAGAIYVPVSLDQPQERRESIYQGAGINVILINESDSKNSPSNDLFFFLDWQTAIKSEPMRSPQDVAPSQPAYIIYTSGSTGTPKGVVISHQGALNTCIAINRRYQIGKNDRVLALSALHFDLSVYDIFGLLSAGGTIVLVSELERRDPIAWCQAIEEHNVTMWNSVPALFDMLLTYATCFNSIAPSKLRLTMLSGDWIGLDLPQRYRNYRVDGQFIAMGGATEASIWSNVFDVEKVPMEWRSIPYGYPLPRQQYRVVDDLGRDCPDWVAGELWIGGDGIALGYFDDELKTQAQFLHIDGHAWYRTGDMGCYWPDGTLEFLGRRDKQVKVGGYRIELGEIEVALNNIPGVQRAVAIAVGNKDKTLAAFIVMDSEQAPIVTAPLDAEEVQLLLNKQLPNYMVPKRIIFLETFPLTANGKVDHKALTRMTNREKKTSQSINKPIITASEDRVAKIWNDVLGPTELYKSSDFFLSGGDAYNAIEVVKRCHKAGYLIKLSMLYRYSTIEAFAIIMDRCRLAPQEEAEL
What is the function of this protein?
Bifunctional protein that plays an essential role in virulence.  Plays a role in both the production of the siderophore anguibactin and the regulation of iron transport genes (By similarity).
What are the official names of this protein?
Anguibactin system regulator.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DEF1_PINSY
Sequence: MAGKGVGSRLSTLFLLVLLVITIGMMQVQVAEGRMCKTPSGKFKGYCVNNTNCKNVCRTEGFPTGSCDFHVAGRKCYCYKPCP
What is the function of this protein?
Plant defense peptide.  Has antifungal activity against B. cinera, F. oxysporum, F. solani and H. annosum with IC(50) values of 0. 4 ug/ml, 2. 9 ug/ml, 0. 9 ug/ml and 1. 4 ug/ml, respectively.  Has modest antifungal activity against C. albicans and T. reesei.  Causes thickening of F. oxysporum hyphae and an increase in their branching.  Lacks antibacterial activity against the Gram-negative bacteria E. coli and E. carotovora.
What are the official names of this protein?
Defensin-1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: NOL12_RAT
Sequence: MGRNKKKKRDGDDRRPRLILNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTVSDLDLSGARLLGLPLPEQGDQDGSQEEEVSSMEKPTKALPKKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE
What is the function of this protein?
May bind to 28S rRNA.
What are the official names of this protein?
Nucleolar protein 12, 25 kDa nucleolar protein.
What is the protein family that this protein belongs to?
Belongs to the RRP17 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IF3_CERS4
Sequence: MARRPHNAPPQRETGPRVNERIRCPEVRLIGANGENIGVVTPSRAMMMAEEAGLDLVEISPNAEPPVCKIMDFGKFKYEQQKREAEARKKQHIIEIKEIKFRPGTDTHDYDVKMRSVLKFLSEGDKVKVTLRFRGREMAHQELGLELLNRVAAHVSEAEAGKVEAMPKLEGRQMVMMIAPK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX606_LYCSI
Sequence: MKLLLFTALVLVVISLVEVEAENERACIPLEKECTKTPGNCCSGLRCDCYRRFEQGVAKGTQCWCIEKDVTYKGV
What are the official names of this protein?
U6-lycotoxin-Ls1f, Toxin-like structure LSTX-F6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 06 (U6-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GNGF_YERPE
Sequence: MRNRTLADLERVVALGGGHGLGRVMSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDTRNCLNQLITEPSVASAMFEYRFTGNGELAGHNLGNLMLKALDHLSIRPIEAINLVRSLLKVDALLIPMSEQPVDLMAIDHEGHPIYGEVNIDQLAQMPQEMLLSPPVHATREAVEAINQADVILIGPGSFLTSLMPLLLLDELTQALRRSSASMIYIGNLGRELSPAAAALSLQDKLTIMESKIGRKIIDAVIVSPTIDISGVKDRIIVQQPLEAKDIPHRHDRELLRQALENTLQQLNGADSV
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_MACCJ
Sequence: MEQKYDVIVVGAGHAGVEAGLASARKGAKTLMLTINLDSVAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKSVIEAQDNLDIMQGMVERLIIEDGKVLGVETVIGTTYLADAVVLTTGTFLRGEIILGNIKYSSGPNHQMPSIKLADHLREIGFDIVRFKTGTPPRVNSDSIDYSKTEIQPGDDLPRAFSYETTEFIMDQLPCWLTYTNGETHQVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQIFLEPEGRNTKEVYVQGLSTSLPEHVQLQMLKTIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKKIQGLYTAGQINGTSGYEEAAGQGLMAGINAAAKVLGHDELILGRHEAYIGVLIDDLVTKGTNEPYRLLTSRAEHRLLLRHDNADLRLTEIGYNAGLIDEFRYSRFNNKKAAISEEINRLSQIRIKPNEKTQSMIESRGGTPLKDGILAIDLLRRPEMDYASVVALIEEQGMIDESVQEQVEIQTKYEGYIQKSLQQVEKVKRMENKKIPENIDYDDIHSLATEAREKLKEVKPLSIAQASRISGVNPADISILLIYIEQGKIKRVN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_ALTMD
Sequence: MAKTLYDKVWQAHIIDQIGEDSLIYIDRHLIHEVTSPQAFAGLNEKGRKVRRPDRTVGTMDHSISTRSLAIDACGPANALQLQTLAKNCEEHNIQLFPVGHQKQGIVHVMGPELGLIQPGMTVVCGDSHTATHGAFGALAFGIGTSQVEHVLATQTLKQSRAKSMLINVNGKLPVGITAKDIILAIIGKIGHAGATGHVIEYAGEAIRGLSMEERMTVCNMSIEAGAKAGLVAPDEKTFAYLEGREYAPKGQDWEDAVAYWKTLYTEEGAKFDTVVELEAADIAPQVTWGTNPGQVIGVNTPVPAPEDFSDPIEKESAVKALEYMGLKPGEKLADIPVNHVFIGSCTNGRIEDMRAAAQVAKRGKVADSVTAIVVPGSGAVKRQAEAEGLDKIFTDAGFEWRLPGCSMCLGMNDDKLVAGDRCASTSNRNFEGRQGRGARTHLVSPAMAAAAAITGRFADVRDYQE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: AQPZ_VIBVU
Sequence: MNKYLAELFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVTIGLWAGGRFEAKEIVPYILAQVIGGVIAGGVLYTIASGQMGFDATSSGFASNGYGEHSPGGYSLTSALVTEVVMTMMFLLVILGATDQRAPQGFAPIAIGLCLTLIHLISIPVTNTSVNPARSTGVALYVGDWATAQLWLFWVAPILGALLGAVAYKLISGSNKD
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KMO_HUMAN
Sequence: MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:29429898, PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702).  Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.  Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: RL29_DEIDV
Sequence: MKPSDMRQLKAEDFQKEIDSRKKELMELRFQAAMGNLAQPHRVTQLRREVAQLNTIRGEQRAGEQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: KAD8_MOUSE
Sequence: MDATTAPHRIPPEMPQYGEDYYIFEMMQNMLEQLLIHQPEDPISFMITHLRRNNDNVPKVVILGPPASGKTTIAMWLCKHLNSNLITKESLLEREFSRLSVEAKSYYQVYKKIPNSILVSLVQERLNEDDCLRKGWILDGIPERREQALMIQTLGLAPKHVIVLNAPDTVLIERNVGKRIDPVTGEIYHTTFDWPPEPEIQNRLRQPEGISEIETAKKLLEYHRHIIRILPSYPKILKTISSDQPCVDVFYQALTYVQSGHRCNAPFTPKVLLCGPLGSGKRLQATLLAQKYGLVNISCGQLLKEAVAAKSSFGELIQPFFEKRMTVPDSIITKVLADRMEQQDCIQKGWVLHGFPRDLDQARMLNSMGYNPNRVFFLSVPLDSILERLTLRRTDPVTGERFHLMYKPPPTIEVQVRLLQNPKDSEEYIKLQTDLFYRNSGDLEQYYDRAIIVNGDQDPYTVFEYIESGIINPLPRKVT
What is the function of this protein?
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
Adenylate kinase 8, AK 8, ATP-AMP transphosphorylase 8.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, cilium axoneme. Note=Located in the proximal region of respiratory cilia.