PharMolix/UniProtQA huggingface dataset:
Protein: CBCO1_MOUSE
Sequence: MNFSIEQYSKFMTLLDMLLHNLQTLHMSLEDSIKWLGEVMAEIGPNHSQKSEDFHVFEVKEANAIIDYLKISLFQHYRLYEFLFYSTREEIVIGTEQTIEVVKPADYPFPAPLEEGISLDTYSTFIEPLPTPDMEQKVLDQEQGTQEALLESEMREEDPLGGFTIDDVKSALERVTDEVLISMQKEISEKLQVQEEAFNARIEKLKKA
What is the function of this protein?
Calcium-binding protein (PubMed:26990073).  May be involved in the control of sperm flagellar movement (PubMed:26990073).
What are the official names of this protein?
Ciliary-associated calcium-binding coiled-coil protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium, flagellum. Note=Colocalized with pericentrin at centrosome of spermatocytes and round spermatids (PubMed:26990073).
Protein: RNFA_TOLAT
Sequence: MLEYLLLLISTVLVNNFVLVKFLGLCPFMGVSKKIEPAVGMGLATTFVLTLTSAFAYLVQHYLLVPLAAESLSTLAFILVIAVVVQFTEMVIHKSAPDLYRILGIYLPLITTNCIVLGLALLNITMQHNFMQSVVYGFGGGLGFMLVLILFASLRERLAAADVPAPFQGIAIGMVTAGLMSLAFLGFTGLIKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y209_SIRV1
Sequence: MSYCLEIIMKIFTFVGFTKHLDELDFDYVVVDKTFNDMSDDQIKKYQEKIIWIMTNTEIRWLRIAKQLLTIVNFAKNIEDDIIAIIDSDLIIPNLREIIPNERIFTPCYWLYYDWANEIRPFCSGTNYIFRKSLLPYLEYTINTYIENEYYKEIPVDIFIHNFIPHMNILKLGTIHYVKTPIGEIKMEFRYEDIQQIFKHIPEFVLLIG
What are the official names of this protein?
Uncharacterized protein 209.
Protein: PO3F2_MOUSE
Sequence: MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQWITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRGDELHGPGALQQQHQQQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGTLPGAEDVYGGSRDTPPHHGVQTPVQ
What is the function of this protein?
Transcription factor that plays a key role in neuronal differentiation (PubMed:24243019).  Binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a non-conserved spacer region of 0, 2, or 3 nucleotides (By similarity).  Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (PubMed:18505825, PubMed:18403418).  The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro (PubMed:20107439, PubMed:24243019, PubMed:27281220).  Acts downstream of ASCL1, accessing chromatin that has been opened by ASCL1, and promotes transcription of neuronal genes (PubMed:24243019).
What are the official names of this protein?
POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RT28_HUMAN
Sequence: MAALCRTRAVAAESHFLRVFLFFRPFRGVGTESGSESGSSNAKEPKTRAGGFASALERHSELLQKVEPLQKGSPKNVESFASMLRHSPLTQMGPAKDKLVIGRIFHIVENDLYIDFGGKFHCVCRRPEVDGEKYQKGTRVRLRLLDLELTSRFLGATTDTTVLEANAVLLGIQESKDSRSKEEHHEK
What are the official names of this protein?
28S ribosomal protein S28, mitochondrial, MRP-S28, S28mt, 28S ribosomal protein S35, mitochondrial, MRP-S35, S35mt, Mitochondrial small ribosomal subunit protein bS1m.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TSAC_XYLF2
Sequence: MATTLTLSEAVTALQQGDVIAYPTEAVWGLGCDPRQETAVHTLLNIKQRASGKGLILVTAELNTLQDWLDLDTLSPERLHEVQASWPGPHTWVLPASTRAPHWITGHHNGLAVRISAHPLVSALCRAWNMALISTSANVAGQPPARRREDLDPSLLPHLAGIVDGPTGGLAQPTSIRDARSGHILRL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4051_SINMW
Sequence: MLKWALIFFVISLIAGFLGFSGISAATAGIAKILFYIAVIIFLVFLVLALAVGGAVT
What are the official names of this protein?
UPF0391 membrane protein Smed_4051.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LHB2_HALHL
Sequence: ADEMRNVSDEEAKEFHAMFSQAFTVYVGVAVVAHILAWAWRPWIPGDEGFG
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B800/850/890 beta-2 chain, Antenna pigment protein beta-2 chain, EHA-beta-2.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: RS8_ECOL6
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MPC54_YEAST
Sequence: MPEDTSYSNSFEDYYNNSHAISPYKDSFYKEMTPSKPNVRFGDDDVNIFDQRKKVNEINKNNTVKRSIPSSISTTITPNKSSLKSPRGKRASKNSFDNETKLESKNETLKEVNDAVNRCYALCNIPTKHVSINSISDLAQTFETLAVGITHETNRKAECERSKNAIDSLYYHEQLEKKELNEKSLQMAIDHLLKVTKQNLRQADDGNKLKETEALKSFIEEIEEVDDNKISINSLQQQLLEEKTANNILRRDYYKLQERGRRLCHEFQELQDDYSKQMKQKEYEVQKLKNEIKVLLNMNDNLKAEKAHYSQKEKQYFQKYTYIEKYMNHVKEEYNRKEDECKKLNFIIDKSMKKIEHLERSLQTQFTAQNSFSTAMIQEEGPKDAHLKDRYHKVKEFMEQKLQTSKINDPSCSEAEALDNVLCLIESSMKTLDKNSKCYPIATKKCIKYVTDSPRLKENEHVTN
What is the function of this protein?
Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation.
What are the official names of this protein?
Meiotic plaque component protein 54.
What are the subcellular locations of this protein?
Prospore membrane. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the ends of spindle microtubules in cells in meiosis. Localizes to all four spindle pole bodies during meiosis, ADY1 is required for this localization.
Protein: RL39_HUMAN
Sequence: MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
What is the function of this protein?
RNA-binding component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L39, Large ribosomal subunit protein eL39.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_NITEC
Sequence: MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLADARTIGVIPWDKKAFSAIEKAIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTEAETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDIQKLTDRYIAEVDKLLQAKEAELMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCGR8_HUMAN
Sequence: MGCCGCGGCGGGCGGCSGGCGGGCGGGCGGGGCGGGCGSCTTCRCYRVGCCSSCCPCCRGCCGGCCSTPVICCCRRTCSSCGCGYGKGCCQQKGCCQQKCCCQKQCCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Small cysteine and glycine repeat-containing protein 8, Keratin-associated protein 28-8.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 28 family.
Protein: Y2205_ANOFW
Sequence: MTHAHITTWVVALILFVVAIALQAKGHEKTKMLHMLLRLFYILIIATGAWILHSMSSFPFLYIVKVIVGLWVIGTMEMILVRTAKGKNTNVLWLQFIVAFVVVLYLGFKLPFGFSFFS
What are the official names of this protein?
UPF0344 protein Aflv_2205.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARMET_DROPS
Sequence: MKTTHLVLVLCFLAGVAQTTLALKEEDCEVCIKTVRRFAASLDDAIKGDYKQIETEFKKFCKTQKNKEHRFCYYLGGLEESATGILNEMSKPLSWSMPAEKVCEKLKKKDAQICDLRYEKQIDLNSVDLKKLKVRDLKKILNDWDESCDGCLEKSDFIKRIEELKPKYARSEL
What is the function of this protein?
Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity.  Essential for maintenance of dopaminergic neurons and dopamine levels (By similarity).
What are the official names of this protein?
Mesencephalic astrocyte-derived neurotrophic factor homolog, MANF/CDNF-like protein.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMLH_MOUSE
Sequence: MWYHKLLHQQSRLRNLMKRGNIAQGLHLSNFKSLFSSSIHWCHTTSKSVNCTWHQHEDHLELQYAGTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDLCIKPKTVHLDETMLFFTWPDGHVTRYDLDWLVKNSYEGQKQKVIQPRILWNSKLYQQAQVPSVDFQCFLETNEGLKKFLQNFLLYGIAFVENVPPTEEHTEKLAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAQQVLQKAPEEFELLSKVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIRYNNYDRAVINTVPYDVVHRWYTAHRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARLLGLHA
What is the function of this protein?
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
What are the official names of this protein?
Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD.
What is the protein family that this protein belongs to?
Belongs to the gamma-BBH/TMLD family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FIBB_BISBO
Sequence: EFPTDYDEGEDDRPKVGLGAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: CRYAB_LITCT
Sequence: MDITIQHPWFRRQFYSFFGPNKMFEQCFGEHIQEADLFPSSVLSPFYFKYPFLRLPSWIESGLSEMRLEKDKFSINLDVKHFSPEELKVKVSGDFIEIHGKHEERQDEHGYVSRDFQRRYKIPVDVDPLSITSSLSPDGVLTVCGPRKQGDVPERSIPITREEKAALGAAPKK
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: DNAG_RICPR
Sequence: MRVTQEFYEFLRNRINISDVVRQKLALTRKSSNYVGLCPFHQEKTPSFTVSDSKRFFYCFGCKASGDVIKFTSNISGLSYNESAIKLANDYGIEIPKLTVKQKEFYEESDNILNILELANKFFRTQLTPEILNYLYKRNITETTIKEFSIGFAPRNNKFEKFFLDKKIDITKLGQAGLIGKCKNGKIYNLFSNRITIPIRNIYNKIVGFGGRVLGNELPKYLNSFETIVFQKSDILYGEHKAISSSYKKNRSILVEGYFDVIALHQAGFNEVVASLGTSVTESHLHKLWRAGDEIILCLDGDNAGIKASIRTINLALPLVNSEKKISFIRLPSGLDPDDAVNKNGADFFAKLIDKRISLSEMIWHIEYSGKNFRTAEEKANLEKNLKDYCNKISDSNLKASYYRFFKDQIWQNLVTKQKKIITPSSNSVLIASSHCYSELEMLEHAFCALLIKFPIMFAEKDIRDFILNLNFNNKSLEEFRNWYLNEIIDNKVKENEITAIVEKTSFFDIFLLLSKADNLFLDISFNKNNIRLDLLWQWLYKKYYLINLQQEYAISINSNHDFEKVLLYKKEIIKIVNELQVLNESFINQTIT
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: PSMA3_STAA3
Sequence: MEFVAKLFKFFKDLLGKFLGNN
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.  Stimulates the secretion of the chemotactic factor interleukin-8 (IL-8).  The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virulence.  Also possesses hemolytic activity, which may contribute to the development of disease.
What are the official names of this protein?
Phenol-soluble modulin alpha 3 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: YNS5_SCHPO
Sequence: MRVLVAETGREDNVSVHSREVSVNGSDSGTGNDAYKLETDDEHPPATPVRGLSTRSQKRPFRPLTIQQDEDVENDTGMNTEYNDDNSSLVNTPRDSTTYAETNSPNTEKLAGRDDDRSLLNLIDRGEIDSKRQRHYVPVHCKRMPKKEITLNQKLYVSQVIGPADAPKSKTIFGKRIMQWEPSQFKESVWASEISKSGKYLATAGKDAIIRVWKVIETPERRETLLKEGPQSCGRFFTPSSIFEPEPVLECVGHNAEVLSISWSKNDFLLTSSADRTVRLWHPKSTKSLAVFRHNEIVTCVAFHPIDDRYFVSGSLDCKIQLWSILRHKILHWTELEYVVSTICFYPDGESIVVGMFYGLCAIYETKNLQYVSSWLIHHSPSRNKKCRVTGLQCASIIPNDSKSDNVVLVSTNDNAIRLYNTVTHALVLKLSDAHRVNGRVLSRLSEDNSYIISGSDTNEVVLWHIPNKVLINASRKRSVILHLPTETFKVCSERLTSTIIAPARTAVEAKESEHDRSLIAEGYNLVKPHSHRSYGTPPVHPIDIIIATNMAGMTIVLCVDYDLGNSHHGFRNSKFGHFVKRLLRT
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C18H10.05.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the cell tip and the barrier septum.
Protein: E3RDB_ADE02
Sequence: MKRSVIFVLLIFCALPVLCSQTSAPPKRHISCRFTQIWNIPSCYNKQSDLSEAWLYAIISVMVFCSTIFALAIYPYLDIGWNAIDAMNHPTFPVPAVIPLQQVIAPINQPRPPSPTPTEISYFNLTGGDD
What is the function of this protein?
Prevents infected cell apoptosis induced by the host immune system.  Acts by down-regulating a number of cell surface receptors in the tumor necrosis factor (TNF) receptor superfamily, namely FAS, TNFRSF10A/TRAIL receptor 1, and TNFRSF10B/TRAIL receptor 2.  Down-regulation of these death receptors protects adenovirus-infected cells from apoptosis induced by the death receptor ligands Fas ligand and TRAIL.  RID complex also down-regulates certain tyrosine kinase cell surface receptors, especially the epidermal growth factor receptor (EGFR).  RID-mediated Fas and EGFR down-regulation occurs via endocytosis of the receptors into endosomes followed by transport to and degradation within lysosomes.
What are the official names of this protein?
Early 3 receptor internalization and degradation beta protein, E3 RID-beta protein, Early E3B 14.5 kDa protein, E3-14.5k.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3_RID-beta family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: UBP4_PONAB
Sequence: MAEGGGCRERPDAETQKSELGALMRTTLQRGAQWYLIDSRWFKQWKKYVGFGSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAEREARLWNKYMSNTYEQLSKLDNTVQDAGLYLGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSPKSSASPYSSVSDSLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDVVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGSDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRSLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKSDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRPSSSQQGLGDDEACSMDTN
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins.  Deubiquitinates PDPK1.  Deubiquitinates TRIM21.  Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface.  Deubiquitinates HAS2.  May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3.  This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6. U5 snRNP.  May also play a role in the regulation of quality control in the ER.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
Protein: TTDR_ECOL6
Sequence: MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDAIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM
What is the function of this protein?
Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol.  Induces expression of the ttdA-ttdB-ygjE operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional activator TtdR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: MSRB_CAUVC
Sequence: MTDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYGCRLCGLPLFKHETKFESGTGWPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHVFPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: SYDND_DESRM
Sequence: MSAESMNGLHRTLYCGELHKQHEGQEVTLMGWVQRRRDHGGLIFVDLRDRSGIVQVVFSPEVDQEAFKKAEGVRNEYVLAVVGRVNGRPEGTINPNMATGEVEVYAHTLRLLNRAKTPPFYIEDNIEVDENLRLRYRYLDLRRPEMHKAMMLRHRASKSIRDFLDQHGFLEIETPMLTKSTPEGARDYLVPSRVNPGKFYALPQSPQLFKQILMLAGMERYFQIVRCFRDEDLRADRQPEFTQIDLEMSFVEAEDVMGLMEQMIAEVCSDTIGVKISTPIPRLSYQEAMDRFGSDKPDTRFGLELKDITPIAAQCGFKVFNSTVAGGGQIKGINAKGCASFSRKEIDDLTAFVAVYKAKGLAYFIINEDGSVKSAIAKFFTEEEIAAIKDKMEAQPGDLLLFVADKPAVVAASLGALRVHLAERLELIPQGMWNFLWVTDFPLLEYDSEAGRFFAMHHPFTSPAEEDLPLLESNPGKVRARAYDMVLNGVEIGGGSIRIHRRDIQELMFKALGMSQEEAKEKFGFMLEAFEYGAPPHGGLAFGLDRLVMLLAGKDSIRDVIAFPKTASATCLMTQAPDVVDPAQLAELHIRSTAPVKKSN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCS1_SYNP2
Sequence: MTVSDSSPNSPWHSFPRKVWRTGLKWIADLRVAIALLLLISVFSILGTVIEQGSTIQFYQENYPEDPALLGFLSWKVLLGLGLDHVYTTWWYLVLLLAFGVSLIACTFRRQLPALKTARNWNYYSQARQFNKLALSTELDHGSLQSLKPQLEKKRYKIFQDGEKLYARKGIVGRIGPIIVHIGMIVTLVGSIWGAFGGFMAQEMIPSGVNFKVNNVFKAGIFSESDRPWSVNVNRFWIDYTPTGDIDQFYSDLSVVDGEGQELERKTISVNHPLRYDGITFYQTSWSIGGVQVQLNNSPIFQLPAAQIPTENGAKLWGSWVPIKPDMSAGVSILMQDLQGSAIVYNEQGELVGAVRVGDRLDVGDISLKLVDLVGSTGLQIKADPGVPVVYTGFLLVMLGVVMSYVSYSQVWALAAGDRFYLGGKTNRAQVAFERELLEIINTLETSHSQATPENTLTSIEQ
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ATPG_RHILO
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSERMGSVLANITQAIGGGGDAPALMTGTGKDNVHLLVVCTAERGLCGGFNSQIARLARDHIRRLLADGKQVKIICVGKKGFDILRRDYASMILDRVDLREVKTLGFVNADAIAKKVIHLFNEGAFDICTLFYSQFKSVISQVPTAQQIIPAGVASAPAAAVDGGNAVYEYEPEPGEILSDLIPRNISVQVFRALLENAAGEMGAKMSAMDNATRNAGEMINKLSITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.