Protein: R1AB_BRV1
Sequence: MSKTSRELTNETELHLCSSTLDLISKSQLLAQCLGTPQNLVSLSKMVPSILESPTLEPRYTSTHSSSLQSLQLLALNTSSTLYKWTTGSISKLRGHLERELCRGLVPLNDFIPKGNYVELSLMIPSVLTGQGTSTTTTLQEMCSDMVQSCIKSMETDLLKGVLALKDQTSCQEYFLSANYQSLIPPQPLVNAMRMSSVVDLSPLILENTRLLLKLSPFHGGTSVSYTSMIREFVDCSRRDEKCLKRRLTKKQKRQEEGSFDANKVITLGGKMYRYRVVILKCSDEVDDLIGFDGKVGEFDYNFENVPHCWRDLVKRRCLIRAKATWNLAGGVDENLDHVYIDESQXDFRCADGSSDSPSACVEDPHLEERIFSRVWLKQTSRFFGTKIQQVSELFKSIGLPELETTYCGVNPVKVGNKWLSFRDQGRSRVFFVYTDSNVYLATTRQKVCCDYILTKFKSVKWIGNKPDQCRVVKVLAWLISVNKVKNCTRVITPMLTVQGKISHRRVDYLDISVLDSYVSDTAGLNCVQKVKKFLSMYYNCGADLGLLDNFLTPIECGTKQLVFERCNCPNHQFYVAQFDNHVVLGLGRPTGVVYPEEIPSCANIYAVGFATQKRVVEVHYYSEMDRHQLPQDYYYFAYDQEFQHVGGDDYVNHHLDDVEDQPFPPVLFDDVYDSGDSLDDGGSDLDCFDVGYDFFWPEAPIPVPSPYGYYQGQRLRDLCVAGGDFGCDCPRCDGTFIYHPFRPRHYHSFDEVGPFIQMCEFTLTYSGQNYNLFYGLEPKVCLQDLVEASDKLLQLLVRGQLENISLPNDILACLSSLKLGANIHPFLWPAPFFNANGEWVDIFGGGDFTVFGEDFCLKAKSMVESVYFLVENFFSVDCPIGNLYCNLHLDGDVKKMLWSTIHMKYIYLALIHSEKVFNIILNSRQLSHQELVKLVIIGTFDVSIVAPCACSGDCNHGKVYNWTNLLSSVYRFVTLDQLVGLSYCEKRSLVLRKVQQYLEVEEGYQRPVQLLMAPFYGFNDNAEPDEQPLTGVFHQQVMQMFDTCVMLDVICGLKRPRASVYNLFGVLADYFRRPFTFRYYQVAEFSGSESTQVFTDVTSALTSKDPCSNRPYIYHDYAVCRVVEPRTAAVTTRGAIYPPEVIEMIRSYLPIEFDVGVMNYVDGNCDFKYCNLEFCLSGRGLVKLDTGELLDYKTNLFVVRYKTLPLLYVTSNPIYLSDFSLDNAVCLTGDFKLSFDVEPGSTLFGLYFTNGRCYRDVWETLPRFGLGTLSPPKCHSKCEPFENLAEVFFFKRRVQLVPLVNNYTPVFRHRPDIPKVLTVELMPYYSSIGYQGFVAPKCVLPGCVATQYCKLRHQLDRCVQVTKLAVAYAFYFKPLNIGSLYHLDPMRGTSYGKPAVVQFEPVGLIKEVNILVYQFGKHVAIHYFPECPTYVAYGHYPSHSVGVWLGYLPSVEECVIAQRNYRVYVPTCFRLSRTGCYHIQQDEDFERTHITVSYHYARDFDTKSLTPMFQMFSKIFGKSKQDLICALNSLSEESQSVLTLFCEEFDSAYTLQTISDEVSFETSTSPELVACVLAYAIGYELCLTVKTDGECESLDVGSSLEQVYVDYDVSKNVWDLSTHLQDDSSDDLELPFNQYYEFKVGRASVVLVQDDFKSVYDFLKSEQGVDYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFGCSVTDSATTLLSNLVDLDKDVVVFVVTNVSDQYIEALGVVESFQSAHGLPNFGNTCWFNALYQLLKSFAVKEQIVQDLVNCFDDFYECPTRQCVEWVCDQLGVVFGEQYDAVEMLVKIFDVFKCNVRVGYDCLARLQQVALGSCREVPADAVLMFFGQDKSGHWVAARKVCGVWYTFDDKVVVKKDPDWSKVVLVLRERGLFKATDFETPRPRRRRVAYRVPRDTISQDAIMFLEERQFSSGTMLAHSCVESVESFHVEGVQPSPLQSVDGLDDVADLSCDNHVCDNSDLQEPQVVVSQPSEVLTTSMSIECPVLENSECSVETDLNPVCEENEQVGESGIKEQDGVTTSDSQQVFSKSLDPIIKQHEVESVEPQDLPVFSQQPQVMLSMTWRDVLFQQYLGFKSDLLSLTHVNKFKIVVYLMVLWFVLLYCFSDFSLLSRFCLYVFLLWLSHVVLVVKKLDLGLVNSGGESYVLRILSSVKVPNCIAFNCDGVHWLILKLLFYSFHFYDFFVKTLVVVFQMPQLRCFTWPLLKLGFADTFLSHHILAFPTKQVSQSCLPVFGDERKYIYVPYWCKESFRTLVARAKQLTATGRTKTLDNWHYQCCSKTVKPSSCFNVRDFVFDDACNNHKHYGFFSALWFYVVFYSGFVSFWLPLMFCYCALFMCTFKNLPVNITRPIRWTVLQQVVDDLLSIITKPLFGRPACPPLSAYLTATTADEAVRASRSLLGRFCTPVGFQQPIMNVENGVAVSSLGFINPLMWPLFIVVLLDNRFVWFFNVLSYIMLPVFVIILFYFYLRKICGCVNVKGVVKNCTRHFQNFSKPLVAAGVHGNRTNFTYQPMQENWCDRHSWYCPKEEHYMTPEMAMFIKNYYNLATSPMADTIWCDYVKSVPNMTWANFKFSLFKSNETVMCGPSSHADSMLLSWYAFLHGIRFAVNPSVIDIPSQTQPIYVSSDSDDSLDKGCDVSLRPTKNKGKFKKQSVAYFSAGPVDLWYYVMLIIALGAIFVFMYSCFMVGQYVVMPRDKFFGVNPTGYSYVNAQPYLHASPPVLRNSDGMVLATPLKVPSISYSVYRLLSGHLYFTKLIVAENECTPPFGAXRLSHEFTCNDFTYILPAHLRIFGRYIMLIHPDQLHMLPFEVEHSTHTRLCYVTGTNIVECLPTFEIISPYVFVVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFKLLFVNTVMVLFVVCLPPLVPGVVFVLALWLCDSVVFLLYLAVLSLFILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLTPDGLTFNGTFEQVSKCVFPLNPLIVNRLLLDCRMSHSDLVEKSKLKTTEGKLATEMMKVFMTGETAYYQPSNFSFQSVFSKVVSPFTLHARPPMPMFRLYVYFNGQCVGTTCTGTGFAIDDSTIVTAKHLFECDDLKPTHLSVELSCRSYWCTWKEPNVLSWKFEGENAYISVENLRDFYGIDFKYLPFQQIECEFYKRMEAVTIYSIKYGSEFATQAWQTVNGHFVCCNTEGGDSGAPLVWRDSVIGVHQGLCDSFKTTLASDSKGVMMTEVKGYHVDPPVYYKPIIMSAAYNKFVADSDVSVGECTNYHNFVNEDFFSMHDELEKVSFGDKMFRYCQSLPRYLEPLHYFHVPSFWQPFKKQSVSSNVSWVVENLHFIFSVYFLVCDFVAYWWLDDPFSVVLPLFFVVQLLSTVVLKNVLFWNTSYLVTLAVTFYVHSEVAESMYLLGLFSDQIVNRVGLILVVSVMCLFVVVRVVVNVKRAIFVVVVSVLLIVVNVVLGVVQFNSLVAVCMFDIYAVFAALLTPQPVVAIMMLILFDTKCLMSFAFVVIVLSFRVFKNYKFVRVLHNLCNFDFVLTQLSLFRYRHHNQGNNPSHYEALWLFLKELYYGVQDVKYEVFSPQAGTYNVRFLTDMTEQDQLEAVEQVQRRLQRFSIVQDKNSQRLVLYSKNVDFLRSQIQHQRVLGANPFIITTLTPKDIAIDNVEVHNPSQFKPEDLQAHMWFYSKSPIFVGQVPIPTNVQTAAVLDTTYNCQDLTADEKNNVAANLQIQNAALTLSLFEECNRFLESELGDVPTLMWQSEDVVDVKQLEVQIEKLRVVLDGMQLGTSEYKATRKQINILQSQLDKALAFERKLAKFLEKVDQQQAITNETAKQLSAFKNLVKQVYESYMSSLKVRVVESNDASCLLTSTDLPRKLVLMRPITGLDNIKIVEKANGCEITAFGDTFTTGLGSNLAGLAYSSTQPLSAYPFIFNLEGIFKQQANIGYKTVECNMSSDNGSVLYKGKIVAVPSEDNPDFVVCGKGYKLDCGINVLMIPSIVRYITLNLTDHLQRQSLKPRRRLQYKQQGVRLGGVNLGEHQAFSNELISSVGYTTWVSSTVCTDKSHKHPWFVQIPSSEKDPEWFMHNTQVKNNQWVVDAKPTHWLVDADTNEQLFALALTDEEYLKAESILAKWSPITQDVECWFKDLRGYYTVSGLQPLWPVCPKKICSLKIVPIFQSQSVAYADEPTHFLSLPVVNKNFLEAFYELQEGFPGEKQVAPHISLTMLKLTEEDVAKVEDILDEMVLPNTYATITNPHMMGQYYVFEVEGLQALHDEVVSVLRQHGIACDQTRMWKPHLTIGEIKDGSVFNKFKDFGITCKLEDCDFVKLGAPKANARYEFIATLPVGDFKLLRDVWCACRHLCFQNGAYQSSRSKHYIDLATEYNAGIVKVNKSNTHSVEYKGQRFMIKRVKDQHEFALARTAFLPSIIPHHMVHQNGEWFLVRGPTTQWSLGDLVYAIWLGDQAYLDECGFVFNPSRDEFLDDANQRSYLANLLEPAILSFCEIFHCVKGCQVPYKITLDNLDLKGQLYDFGDYPCPNKVDNQSALFVLAEVWSMTRKPFPTKFAQVLAKEMNVPADFQMYFQHTLLSGKYFDKAMCLNNVRPLLRDPANLTTTPFFSQHSGVWTHFYNPIYGLVECDLEEFSNLPEVLQQLITVQGPITSAMTPAISIGEGVYAANVPPVAAAKQKIPLYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCFYDYQGTGFYSPKLLAGVYDFMKRVTTCYKTDERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENITKLFEYAQKAPLPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSQGFCLIGVSKYGLKFSKFLKDKYGAIEQFDVFGSDYTKCDRTFPLSFRALTAALLYELGGWEEDSWLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDLSDCNKVMRIAAHNAYTTGDYGVFNTLLEEQFQTNYFLNFLSDDSFIFSKPGALKIFTCENFSNKLQTILHTKVDLTKSWATTGHIEEFCSAHIIKTDGEYHFLPSRGRLLASLLILDKLSDVDIYYMRFVAILCESAVYSRYQPEFFNGLFQVFLDKVQQFRKDYCCDPCPTQLLDRQFYENLVFTSNTEVGLVDCYLENFKLQCEFKQQAGFDRVCFCCPNPAVSVCEECYVPLPLCAYCYYVHVVISSHCKIEDKFKCPCGQDDIRELFIVLNNSICIYQCRSCVESDRLRISLLSDVDQVVRLPGFKANSASIAKNGVAQLLTPVDNVDVSLDWNHQETVQQNVARIVYHSANMTQMSIEVVYVNFSLVRNDGSSAILDIPNFKCPDTSYCLFYKPGKTGVLKFTGKGTLTSCYDSNNLTWFKVTCPDFNQPWRLATCFVIQQHDAVYPPIKSTQYENVTFVMGPPGTGKTTFVYNTYLSKASPSNRFVYCAPTHRLVGDMDEKVDGAVVVSAYNDRTYRNPVWKKDDSYDVLLCTHNTLPFIKSAVLIVDEVSLIPPHVMIKILSMGFKKVVLLGDPFQLSPVYKNHKVHFKYDTFYLLQLATQKRYLTACYRCPPQILSAFSKPYCDVGVDLVSFNNKPGKFDIIVSKQLANMQDFSVLSVLSKEYPGYVILVNYRAAVDYAMQNGLGDVTTIDSSQGTTAANHLLVLFGASNFSKTINRVIVGCSRSTTHLVVVCCPELYKHFQPILNWPEPVYRYFGMEKQSDFNIIPEVASLVFCDIEFWHYKADPNSKTRTVYPGQIAVVTSQTLQLYLGVFDDAGYKSALRGLPKDVFVPPNWVWMRKHYPSFEQHAYNMQRLFKFIIDTTCGQPWFILYSCSNDLKSLKFYVEFGTNYFCSCGELAICLMRDGLYKCRNCYGNMSISKLVNCKYLDVQKERIKLQDAHDAICQQFHGDSHEALCDAVMTKCLYLASYDAAFKDTIHVKYKDLCLEIQYKITSPYVRYDGVNKRYLYRDHGAMHYFKTPKSPMQNVYRYEVGAHTEYSINICNSYEGCQSFGKTCTKCIHIHCIVEQFMADDRYRDFILVSVVKSDFVEQALSPAAKALMLTVTRVEGKSFYTSNGQRYDLYDYDLSKSVMRVVGASVKPLPLYSVVVGLGINCTVGCVLPNVPMKLKDELLSTDVPLSTLRLDLPTWYYVTWPTLSNRTSRWKLAGAQVYDCSVHIYVEATGEQPLYYLQLGNGESLRELPETLFSTGRLYNLEHDPSKNFNVQQLAIETIPKNHHVFAGDFTDVGTDIGGVHHVVALNGYKGSIIPNYVKPIATGLINVGRSVKRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGEDDIQTFYPQKEFIRSYYEWPTILPELESHYDLKNYGQDPQFMPQPVNFAKYTQICTFIQEHVKVARNSLIWHVGAAGIDGCSPGDIVLSSFFKECLVYSWDVKDYDTLLEKHNYDCNFRPNLIVSDVYNVSSNVSEVLEDCVHRLALGGTIIFKTTESSRPDIQLSKVTKYFAAVHFFTAGVNTSSSEVFVVLKYKLHSEPIGEELCSPNILRRIAAYRNKLCIVPNFKVFSTSLSYRFSSVKFVQKCFYVSVPRQFCASGLIQEVPLLCQMKH
What is the function of this protein?
NendoU is a Mn(2+)-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond.
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
What are the subcellular locations of this protein?
[Non-structural protein 1]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 2]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 4]: Host membrane; Multi-pass membrane protein.