PharMolix/UniProtQA huggingface dataset:
Protein: TRE12_DROSE
Sequence: MKILMRADTHVSYSVPAEGTKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSILAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKDLMQSQAEADSQATRNTCLELFKRINLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLCTIIVGIVNFFATFMGIILIDRLGRKILLYVSDIAMILTLSILGGFFYCKAHGPDVSHLGWLPLSCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGPHGAFWLFGVVCIVGLFFVIIYVPETRGKSLEEIERKMMGRVPISAVVNIKPFSFNM
What is the function of this protein?
Fails to transport trehalose.
What are the official names of this protein?
Facilitated trehalose transporter Tret1-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPZE_METRR
Sequence: MLSIIHVGWLELVWFVALYPFACWTLFAVLKSVYRITLHPLAKFPGPKLAGASYCYEFWYEIVCGIQYTQKIIKLHEQYGPIVRINPDELHFNDIDFVDVVYTAGARKRDKSRHYLAGFEGSIIRFVSSDFHSFLIDTRVKKPERLKRVVLGAERHHDAKDCPMFLELLNSNLPAQEKSKQRLMYEANGATLAGSGSTAIALSNIVYNLVANPRIGHKLRSELMRKVSASKNLPTWSTLEELPYLTAVIHEGLRSMYDPSKERLPYDPSQERLPRVATEEELIYEGGSALGKSKYVIPRGYAISTSAHVVHSDESIFPNASQFDPERWLDRDGQRNKELERHLLSFSKGSRHCLGMHCRRATCLAIPASARNGTSGYQFTSGQLEYKVQERQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pyrrolopyrazines, secondary metabolites showing insecticidal activity (PubMed:30452111).  The single multifunctional NRPS ppzA is responsible for the biosynthesis of peramine (PubMed:30452111).  The condensation domain of ppzA is proposed to catalyze formation of a peptide bond between 1-pyrroline-5-carboxylate and arginine (By similarity).  The methylation domain of ppzA would catalyze the N-methylation of the alpha-amino group of arginine (By similarity).  The reductase domain is proposed to be responsible for reduction of the thioester and the cyclization to form an iminium ion resulting in release from the peptide synthetase (By similarity).  Deprotonation of this intermediate and oxidation of the pyrroline ring would give rise to peramine (By similarity).  This final oxidation to give the pyrrole functionality may be spontaneous (By similarity).  In Epichloe species that produce only peramine, the peramine synthetase gene is not localized in a gene cluster, in contrast to Metarhizium rileyi that contains additionnal pyrrolopyrazine biosynthesis genes (Probable).  The 2-oxoglutarate-Fe(II) type oxidoreductases ppzC and ppzD could be candidates for conversion of proline into an oxidized derivative to be used by the ppzA A1-domain as substrate (Probable).  The other ppz genes encode proteins predicted to derivatize peramine into more complex pyrrolopyrazine metabolites (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase ppzE, Pyrrolopyrazine biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IMQI_ASPFN
Sequence: MSSGEPTTMTPSPSERTPLLSNGSGGAADDGGTTVTISKPNDGVRRIADSLPLSVWLISTIELCERFAYFGTIAPMQNYIQNPRNDPLRPGGIGKTASTMIYPAV
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of imizoquins A to D, tripeptide-derived alkaloids that serve a protective role against oxidative stress that are essential for normal germination (PubMed:29182847).  ImqB is a canonical three-module NRPS that assembles the tripeptide backbone of the imizoquins via condensation of Trp, Tyr, and Leu-derived precursors (PubMed:29182847).  N-methylation by imqF and phenol oxidation by imqC, followed by cyclization via the FAD-dependent oxidase imqH carry out the three-step transformation of L-tyrosine into tetrahydroisoquinoline (PubMed:29182847).  Importantly, this sequence requires the presence of a free amine in the tyrosine moiety, indicating that isoquinoline formation occurs prior to peptide bond formation (PubMed:29182847).  The imidazolidin-4-one ring of imizoquins could form following additional oxidation of the methyl-derived bridgehead carbon by imqH (PubMed:29182847).  Lastly, O-methylation by imqG and leucine hydroxylation by imqE complete biosynthesis of the imizoquins (PubMed:29182847).
What are the official names of this protein?
Imizoquin biosynthesis cluster protein I.
Protein: RL22_CAMHC
Sequence: MSKSTIKFVRLSPTKTRLIAKEIQGMNAEFALATLEFTPNRGAKYIANAILSAVANGGFEPNEVIVKSCRVDAGPVLKRFRPRARGTASRIRKPTSHIMVEVSKPSKEA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YL8B_SCHPO
Sequence: MSNLILTPSNNGTERPYRSRKTRPCDNCRLRKSRCVVESIGNPCLLCTQLKIPCTYHLPPIKRNKQKKQQDSVSDDTPSEATTTTNDDRDPKYNALGNNLDAVRGKVISPTQGSDARGPDGRQVPLNLAGITEMYHTSDDKFDKLGLDDSLNYPYVLGPTCDSDIDLIREYFSFENGVCSFDNMTVKYVSTSSKSPVMYILDPAYENDRHSDFSRYDHALHDLLSTYIDEATGRTLVNLYFSHVHPSYPILHGPRFLLSYKNGSRNVPSILLAALYSVALTYWPSDSRSFGAPPLDQRKMWTIVEEGLNFHFTQPRLSTIQAALLYLISRPLHNMYSLSSILSRTTVLSQLLGFNHDCTEWKIPNEEKTIRKRIWWAIFIADKWYSMYFGLATNIHEDDFVVPKIESDESLPLEITSSHSFKTFLKMIELSSLLQDILQDLFTVRALTRHSKNNRSISYQIIGFFTRLNSIRPVEFTEPALGVASLKIQFDAVEILLWKTALRFNLPDFQSADDLFVCVEKSVSNFVQITANSSGDFFWPYAGFHFSTLVSLLIRLHLDFHTNNTYGARAFSLLDAFVRHCITLHEAGFDFVEMAIRRSSSLLKELGKDHPHLLALRDDIFNSNDSRGEEAYNHVPEQLFDPWNPHSWTFPKSD
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C25B8.11.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARGC_XYLF2
Sequence: MSTATFTLGIVGARGYTGAALITLLTAHPAIELIFVSSREYHGQPVAAHNPTYCGDLRFETLDPAAVAAKRADVVILALPNGNAAPYVHAIDATAPPTLIIDLSADTRFDPDWYYGLPELTRHTYTGQKRISNPGCYATAMQLAIAPLRDQLAGPPQCFGVSGYSGAGTTPSDKNNQALLRDNLMPYALTDHLHEREVSAQLGIPVEFMPHVAPHFRGITLTANLWLQRPLTREHIKTLYATRYANDPLIDIIDPPPWVNQIAARHTVQIGAFTMAPGNKRVVIVATLDNLLKGAATQALQNLNRALGLDELTAIPYQPNPVPSPIP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_GEOKA
Sequence: MMHHLIQEITKEQLRTDLPDFRPGDTVRVHVKVVEGNRERIQVFEGVVIKRRGAGISENVHGPQSVLWRPALSAHSRVHTPKIAKLEVIRRGKVRRAKLYYLRELRGKAARIKENTNAAQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HIS1_ANADE
Sequence: MPGTSELITVAVPKGRLLQESSALFERALGVSPRKLLEGTRKLAADAPEAGLRFISIRAGDVASYVEHGAAEVGIVGLDVLREEPRDLYEPLDLGIGRCTVIVARPKGARPLPRGVAPRVATKYLSLAARHFAAKGVPAEIIPLHGSIEVAPSLGLADTIVDITETGETLRANGLVIEEKVLEVSARLVVNRVALKLHPERLRLLIEALRAAVAAADAEAR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_ANAMF
Sequence: MHPVDKKSLALKIYEATGYQFRDLDLLLEALTHPSLSYKSAANYERLEFLGDAVLSMTVSEMLYRLFPDDDEGCLTRKRTALVRGSEVVEIARSIGLGELILMSGGERTCGGSDNPGTLENALEALIGAMYMDGGPEAYRSFIHKHWLARAQHMSYTPPQDPKTALQEWVQGRGWAMPLYKLVSKSGPEHKPVFAVEVSIQEHGNVLGTGSSKKLAEQEAAKLMLKKITELP
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_PROM5
Sequence: MSSLFFTHFALKTIGTLGGGLSDFPWLSISILFPIASAFLIPFFPDKGEGKEVRWFALSVALITFLVTVGAYINGFDINNENVQLKESISWLPKLGLTWSVGADGISMPLILLTSFITALAVLAAWPVKFKPKLFFFLILIMDGGQIAVFAVQDMLLFFLTWELELLPVYLLLAIWGGKNRQYAATKFIIYTAGSSIFILLAALAMGFYGTEVPNFEFAHLANQNFSQNFQILCYIGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPVAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGATYDRTKTLKLDEMGGVGQKMRIMFALWTACSLASLALPGMSGFVSELMVFTGFVTDEVYTLPFRVVMASLAAVGVILTPIYLLSMLREIFFGKENPKLTEDRNLIDAEPREVYIIACLLLPIIGIGLYPRLVTESYLATISNLVDRDLNAVKSVPKTNIFAGNKKSQILKAPTI
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: LEPA_EHRCJ
Sequence: MDESNIRNFAIIAHIDHGKSTLADRLIEECNGLDKREMKDQVLDSMDIERERGITIKAQTVRLVYKAKDGQTYYLNLMDTPGHVDFSYEVSRSLAACEGSLLVVDSSQGVEAQTLANVYKAIDSDHEIIPVLNKIDLASSDPEKVKLQIEDMIGIDASESLLVSAKSGVGIQDVLEAIVSKLPSPCGKSDSPLKAILVDTWYDTYLGIVILLRIKDGVIKKGMKIVMMSNNAVYQVDNVGIFTPHKKIVDQLSVGEIGFITASIKELSDCKIGDTITEEQRRCDAPLPGFRTSHPVVFCSIFPNEAGEFDRLREALKKLQLNDASFTFEIEVSNALGYGFRCGFLGMLHLEVIQERLEREFNLDLTATAPGVIYKVTTKSGEIREVHNPHDFGETQDIANIKEPWICATIMVPDQYLGVIMSLCNNKRGEKLDLSYSGNTALLKYRLPLSEVVFDFYDRIKSLSKGYASLDWEMDEYLDSEIAKLSILINSEPVDALACIIHKSKVEQRGREICLRLKDLIPRQQYKIAIQAAIGGRIIARETISPYRKDVTAKLYGGDVTRRMKLLEKQKKGKKKLRSIGNVNVPHNAFIQALKIID
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ASSY_RHORT
Sequence: MKKGDVKKVVLAYSGGLDTSIILRWLQDEYDCEVVTFTADIGQGEELEPARQKAEMMGIKEIYIEDLREEFVRDYVFPMFRANTLYEGVYLLGTSIARPLIGKRLVEIAEATGADAVSHGATGKGNDQVRFELTAYALKPDIKIIAPWRTWDLHSRTKLIEYAMRHQIPVPKDKHGEAPYSMDANLLHISYEGKALENPWTEPSEDMFRLTVSPEAAPDKAQYIEVDFERGDAVAIDGEKLTPAALLAKLNEIGGRHGVGRLDLVENRYVGMKSRGVYETPGGTILQVAHRAVESLTLDREVMHLRDELMPRYAKLIYNGFWFAPERLMLQAAIDQTQQTVTGTARLKLYKGNVSVVGRKAAKSLYRMDYVTFEEDTVYDQHDAEGFIKLNALRLRLGKMARDS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_DINSH
Sequence: MARSRFDTGSGPSQRQLRVGELIRRTLSSVLNQGDIHDPDLNRMSITVGEVRTSPDLKVATAYVLPLGGHGAQDALDALRRNRHELRRAVSKELTLKFSPELRFQIDETFDRMDETRRLLSQDHVRQDLDKPDED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPSBF_MENPI
Sequence: MATNGVVISCLREVRPPMTKHAPSMWTDTFSNFSLDDKEQQKCSETIEALKQEARGMLMAATTPLQQMTLIDTLERLGLSFHFETEIEYKIELINAAEDDGFDLFATALRFRLLRQHQRHVSCDVFDKFIDKDGKFEESLSNNVEGLLSLYEAAHVGFREERILQEAVNFTRHHLEGAELDQSPLLIREKVKRALEHPLHRDFPIVYARLFISIYEKDDSRDELLLKLSKVNFKFMQNLYKEELSQLSRWWNTWNLKSKLPYARDRVVEAYVWGVGYHYEPQYSYVRMGLAKGVLICGIMDDTYDNYATLNEAQLFTQVLDKWDRDEAERLPEYMKIVYRFILSIYENYERDAAKLGKSFAAPYFKETVKQLARAFNEEQKWVMERQLPSFQDYVKNSEKTSCIYTMFASIIPGLKSVTQETIDWIKSEPTLATSTAMIGRYWNDTSSQLRESKGGEMLTALDFHMKEYGLTKEEAASKFEGLVEETWKDINKEFIATTNYNVGREIAITFLNYARICEASYSKTDGDAYSDPNVAKANVVALFVDAIVF
What is the function of this protein?
Involved in the production of (E)-beta-farnesene, an aphid alarm pheromone.  Can use both farnesyl diphosphate and geranyl diphosphate as substrate, but not geranylgeranyl diphosphate.  Produces mainly (E)-beta-farnesene, but also smaller amounts of (Z)-beta-farnesene and gamma-cadinene when used with farnesyl diphosphate as substrate.  In the presence of geranyl diphosphate, produces limonene, terpinolene and the acyclic monoterpene myrcene along with minor amounts of gamma-terpinene, (Z)-ocimene, (E)-ocimene and sabinene.
What are the official names of this protein?
Beta-farnesene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC78C_DROME
Sequence: MDVELEEEEERICLRTAEEGQLANMDDDKLVSDEVHLRQLSATPSSAFSLQHSRGSDTKEEAPPEGGTMGGKSAAPREEGEPDERVVLRRAVDKGAIALAQIDDLKLEGDDDDEAVVNGEEVDGLGLSNPAAQTTDDEQITVNGTGAAATSSVAADAASSEQDAASTAMATPDMSKIPRLPGDGAQMEDNGSGDLPPSLRASTTSILSNLRKKQQGGPLRGGVAKQTPLRVQSVRIVEAKRAYGPKRRTESCSIFGNSNFEHDLESGNSLASIPGQSQRPLNNEMYSAFKSGNVVKGILCPSLTNSFKQSSLERSYLTYTHRQRQKSLIIVNVVDFVLKIVLAFVWIMRRSELGPIESDDGTSMATAITWSVCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQGVGFADREYLVWYILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQHGEATINPECVLFQIFANFILYTAINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKLLDSILPNIVNNQIRSEMYKGTDPTVETQFNKLYVYPMDNVSILFADIKGFTELASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQFESDNWKTRPDHAVCSVETGLHMIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGRVHISEATLKCLNDAYEVEPGNGGCRDNHLKMLNVKTYLIKRTEPLRPKRRFGTRSSAHLAGSVATAAPPCATPTALPKSISASGSGSIGGVTATGNDGASIDGRSLEYAATIAVPAQQPTQLLQQQQKKNISLNSLPNVVEGVAMDSRRIRNGCGVMGGAGGTGGGGTGPCGMSTVSSPTAMMSAPLEVQLRPRNGACSIQNLAEAIDGKGLIIEDESTTDWIPEIPFKNLNSPEDGLNRADSILVDTKEDHRVSVAVLDEEIDEFIEQNIQINSNKEIRREYLNPWTLKFKDKSQEQKFCQLREDMFRSNMLCVFVIWIFMVLCQVIIIPRCTRLIICLSVGTVILTFCCVLVMAEEFPGLPRCLKTNSAKLVHQRQRRTLFICGVIVSMCMLSAIGLVLCPSSTYIGTADEHSRFLRMVSPYSNISMTEKEFKLNVYLSATIHHNITISTPASGGPTPLVDITSSGPSDEFVRSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSSDVEGQCAHPEYLVFTWVLCLVSLATALKLYYLVKALMALAMVAFYTTLIMMKFGSGDSFSLVELSRLGMPLGVQMLILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLSDEHTDELYSKMHNLCGVMFASIPNFQDFYSEDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGLNHEHLRLRGETSEDSVCDLVEFAFAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTTFYVHPKGISESQLISPVRMPAGIPLAQTPNLQRQTSHHGSFSAVVFGMLQASKRSTAIAGTPTGTPSPQIRRGHRGSTFSSVRLSQKSTTVNPVRRNTTRVRGRSYRQKKSSSNNSIVTQASSSYMPSFRRIDQIETTISKSHNDAL
What is the function of this protein?
Does not have adenylyl cyclase activity and it is not involved in taste perception.
What are the official names of this protein?
Adenylyl cyclase 78C.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCR3_YEAST
Sequence: MARQKLTFKEQMDGFPWVQLVVVSLVRFSEPIAFSSLFPYVYFMVRDFNIAPNDAQVSKYSGYLSSSFALCQVISAYHWGRFSEKHGRKITLTCGLIGTSVSLLILGFSRNFYQALVARSLMGLLNGNVGVIRTIIGEIATERKHQALAFSTMPLLFQFGAVVGPMIGGFLVFRDGTMNEVPLWFPHFAKRIIRSYPYALPNVVVCMFLMFGLTNATLFLEETHPAFKDRRDYGLEVGDFIKKNIFGIQPKRRPWQKRIQDDSENIHHRNENVNSIRGQDSEEDENSPLVNTTNDDDTESIQSIDPILTRRQSVGLIRTYSLHEPTDAVHANIDTAPDGCKESSIFHHVFHTKVFYPISVNFIMALHLIVYNEFLPVFLAYDLAVDPENPKKLASKFPWKISGGIGYEPEQTGTLLSTTGIFGCFVVIFIFPIVDRNFDCLTIFRTLVKLYPIMYVMVPYVVFLQNERIPSWYTVVYLYIITGIKTFCGALTSPQIMLLIHNSSPLSCRSVINGATISISASARFIGPLVWGYIMSWSQQNDVAWVSWWSLSLFCMVALYQSYKIAPIDDNENELHGQGSEDAYNSQSQSSDLRMAHRSSLSSLSNQRCTT
What are the official names of this protein?
Uncharacterized membrane protein YCR023C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAN_YEAST
Sequence: MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK
What is the function of this protein?
Catalyzes the reversible hydration of CO(2) to H(2)CO(3).  The main role may be to provide inorganic carbon for the bicarbonate-dependent carboxylation reactions catalyzed by pyruvate carboxylase, acetyl-CoA carboxylase and carbamoyl-phosphate synthetase.  Involved in protection against oxidative damage.  Encodes a substrate for the non-classical protein export pathway for proteins that lack a cleavable signal sequence.
What are the official names of this protein?
Carbonic anhydrase, Carbonate dehydratase, Non-classical export protein 3.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion intermembrane space.
Protein: PKRI1_MOUSE
Sequence: MASPAAASVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMNEWAPRAPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQKEEPSQCQEQHASSSDEASETEEEEEEPSVVIMGR
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (By similarity).  Binds double-stranded RNA.  Inhibits EIF2AK2 kinase activity.
What are the official names of this protein?
PRKR-interacting protein 1, Protein C114.
What is the protein family that this protein belongs to?
Belongs to the PRKRIP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: TKN3_PSEGU
Sequence: QPHPNEFVGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Kassinin-like peptide K-III, PG-KIII.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GNAS3_RAT
Sequence: MDRRSRAHQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQRAAQRRSFLNAHHRSAAAAAAAQVLPESSESESDHEHEEAEPELARPECLEYDQDDYETETDSETEPESDIQSETEFETEPETEPETAPTTEPETEPEDERGPRGATFNQSLTQRLHALKLQSADASPRRAQPTTQEPESASEGEEPQREPLDEDPRDPEESEERREANRQPRRCKTRRPARRRDQSPESPPRKGPIPIRRH
What are the official names of this protein?
Neuroendocrine secretory protein 55, NESP55.
What is the protein family that this protein belongs to?
Belongs to the NESP55 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Secreted. Note=Neuroendocrine secretory granules.
Protein: DDL_ACIAC
Sequence: MAAGLPETEIDVRALGKVAVLMGGDSAEREVSLMSGGGVLQALRARGVDAHAFDPSQSDLSELKSHGYARCFIALHGRHGEDGTVQGALELLGIPYTGPGVMASAIAMDKIMTKRIWRFEGLPTPDWRLVSSAAETAQALEDLGSPMIVKPSREGSTIGLTKVTSPGQCEQAYRLASRYDPEVLCEQFIEGEETTCPVLGQGAGAHALPVIRIVAPEGNYDYQNKYFTDVTQYHCPCGLPEQEEREIQRLVVEAFRTLQCRGWARADIMIRASDRKPFLLEINTSPGMTGHSLVPMSARAMGVSYEELCLRILAGASLDARQGQVDAAGHPGAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_SERP5
Sequence: MRLTPTHIKGIKVAIYLAAFLPFLWLVLSVDQGWFSADPAKDIQHFTGRMTLKLLLATLMIAPLARYTRQPLLIRCRRLVGLWCFAWGTLHLISYSTLELGLSNIGLLGRELVTRPYLTLGIISWLILLALAATSTLWAMRKLGAKWQTLHNLVYLVAILAPIHYLWSVKTFSPQPFIYALLAVVLLALRYKKFRNWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU2M_DEBHA
Sequence: MTFTAFTMFLVFSTFSQSMMVNRTGTITIMFTTMLFFLSMDIVAMSPGMTLFNNWFNLTPYNLPLSFLMLSLIVMLLMYSTSNHRYDLKSPFYLLLLLTNMMGLLLFPLVNDLIALYVVMELQSYSLYLLTGLHSRSYNSSRASLLYFLMGGVASTIMLLASYFVYALTGTTNLSDMAMFYSYSNAFDYFDILLVALLFKMGMAPLHRWSIAVYNYAPTYITAYISMVAKMSMVSWIFANANLFHHHVTILFFYISLAMAAYKPLFQVNIKTMLAYSGMLNFSYILLSMMSYDPAFYIYMIQYVLTHLILFLGMLGASQYVNSPISIWSPLTFMHQLKLPNLTLAFSLILALFSLIGMPPTPGFYAKLFVLSAALQDNYVLETCAIVVCSVVATYYYANMIKVLFNSSTQKVTNFINPSLAFTMASATSLLFSFFMFMPSLSEGLYLITL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.