PharMolix/UniProtQA huggingface dataset:
Protein: THIC_IGNH4
Sequence: MTIYKDARNGRITEEMKKIAEVEGVDPEFVRRGLAAGRIVLLRNLKRADRVKTVAVGEGMLTKVNANIGTSNTLIDVNMEVEKAKIAKKYGADTVMDLSTGGNLDVIRRKIMEAAEPLPLGTVPIYQAFMDVATRKGAGLYMTEDDILNTIEKHLKDGVDFMTLHAALTRDLAAKAVKSDRAEPIVSRGGSILAAWMLEHGKENPLLSNFDYILEMFKEYDAVISLGDSLRPGALEDAHDEYHLSELMVNARLVKRAREAGVQVMLEGPGHVPLDRVVADVKLAKRLTEGAPYYILGPLVTDIAAGYDHIAGAIGGAIAAAHGADFLCYVTPAEHLNLPNPEQVREGVIAFRIAAHAADIVKYPDRAMKVDIEMGRCRGRLDWECMIRLSLDPDKAREIRNQYGPTSIKSCNMCGSLCVFLLLDKWRRKKDEELHAPLA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MNMG_ALIB4
Sequence: MNYDVIVVGGGHAGIEASLASARMGKKTLLITMLVEQIGAASCNPAIGGLAKGHLVRELDAIGGEMGLCTDNTGIQFRILNASKGAAVQGSRAQIDMDKYREYMRKVCHNTPNLEVYQDEVTALLVKNDNEVCGVKTKLTEEFIAKKVVLTTGTFMRGLVHIGENKYEAGRAWELPSTTLSTQLKELGLRVGRLKTGTPSRLDANSIDFSVMDMHGGDVNPAPFSFRTNKSDFAPTQFPCYITYTNEKTHEIISSNFYRAPLFTGQIEGLGPRYCPSIEDKVNRFAERDRHQLFLEPQTAMCTEYYINGMSSSLPIDVQKAMIHSVKGLENAKIIRYGYAIEYDYVDPTELKHTLETKKIKNLYHAGQINATTGYEEAAAQGLIAGINACLSIDEKEPFILRRDEAYIGVLIDDLVTKGTNEPYRMFTSRAEYRLLLREENADLRLSQYGHKFGLIDDETIKKVENKRKTIEEAIEFMANEWMTSKKETLELLESIGEEKINDRVLLVDLIGRNSIDIFKFEKLVPSFAHLDNYLKEQIIIEAKYYRYIQKQQKQIEKMKKMLKATIPESFSYKGLPGLSNEVVEKLEKHRPPTIFNASLISGVTPAALDIIHLNLNIFVTNTKK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS2_SAGLB
Sequence: MVPKLFTSQICLLLLLGLSSLEVSLHAKPQQFSWAQWFRIQHIQTTPLHCTYAMRAINRYQPRCKNRNTFLHTTFADVVNVCGNTNMTCPGNASLNNCHHSGVRVPLTYCNLTGPQTISNCVYSSTQANMFYVVACDNRDPRDPPQYPVVPVHLDTII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: GIPR_MESAU
Sequence: MPLRPRLLLLCLWGLLLQQAETDSEGQTTGELYQRWERYARECEETLTAADPPSGMVCNGSFDMYVCWDYTAANTTAQASCPWYLPWYRHVAAGYVFRQCGSDGQWGPWRDHTQCENPEKNGAFQDQRLILERLQVVYTVGYSLSLGTLLLALLILSLFRRLHCTRNYIHMNVFLSFMLRAVAILTRDRLLPTLGPYPGDRTLTLRNQALAACRTAQIVTQYCVGANYTWLLVEGVYLHHLLVIVGGSEKGHFRCYLLLGWGAPALFVIPWVIVRYLLENTQCWERNEVKAIWWIIRTPILITILINFFIFIRILGILVSKLRTRQMRCPDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQAEGTLRFAKLAFEIFLSSFQGFLVSVLYCFINKEVQSEIRRSWRHRVLHLSLRDERPCPHAELGPQALPSRSAPREVPITGSTLPSGPLHGPGEEVLESYC
What is the function of this protein?
This is a receptor for GIP.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBRG1_XENTR
Sequence: MNHSPATTFSPHSRYQELKVRNKKSTKKSHKEKYRLKCLRLRRVAKDMVFENAALCDEIARTEDKFIRAKEERRFLLKRLLQLQALSEEEPGTSHNSNVSAGYSVPDMAAMNEGNLDMCYSSVLDDGGSCKKVKKDKREKGKENKSEAMKKPSKKKRVTEGTTRKWVQPIALDPCGRPVFPIVLEGLTVYSLGEIISDRAGFHEKVAIYPVGFCSTRVYVGMKNPDQKCLYTCQIKDGGTGPQFEIVPDDDPQNSIVASSADECHSILLQKISTPLGKRFSTPDLAGAYFFGFTHPTIQNLIQSCPGARKCTGYQWVKFEVCRAGEEQVPRDICESSASVNFEAFQRQSFATINNSTALAGTLDLPEIHASHDYISTYQEIFLSHSQLASGMQHLKSPSNQYSPSRSSE
What is the function of this protein?
May act as a growth inhibitor.  May be involved in maintaining chromosomal stability.
What are the official names of this protein?
Transforming growth factor beta regulator 1.
What is the protein family that this protein belongs to?
Belongs to the TBRG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_XANCB
Sequence: MRHQKSGRKFNRTSAHREAMFRNMAASLFKHELIKTTLPKAKELRRVAEPLITIGKVDGVANRRLAFARLRDKEAVGKLFVELGPRYATRPGGYLRILKAGFRAGDNAPMAYVELVDRPVVAEEVSE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL23_STACT
Sequence: MEARDVLKRPVITEKSSEAMAENKYTFDVDTRANKTQVKIAVEEIFDVKVDKVNIINYKPKKKRMGRYQGYTNKRRKAVVTLKEGSIDLFN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UGPA3_ARATH
Sequence: MANPQASPILHHPQNHLSLFHFRTTTSPRSFSSLHFRKPLLFLSSSSSFSSKLQQSEQQCNNHQVRHVSTVPVEYSTPTPPESDDFLSEIDRLKSLLSKLDVSKDLRRKDAVIDADSRVRRFFSENRGGLSKVFGYLGLNSNEMFLVKCVIAAGQEHALCMNYEEAFGEEEEEYTVRSSVKNALYALVEMIERFDVNSSGYKGRREMGTVLDSEEIAHFRKFLTFLEEIEQFYDCIGGIIGYQVMVLELLHQSSKRRNTNRSQLVEESLGCQYLEMHTPSVLDLTQEEDYASQAALWGIEGLPDLGEIYPLGGAADRLGLIDSETGECLPAAMLAHCGRTLLEGLIRDLQAREFLYFKLYGKQCVTPVAIMTSAAKNNHEHVSSLCERLKWFGRGQSNFRLFEQPLVPAVSAEDGQWIVSKPFVPVSKPGGHGVIWKLAYDKGVFNWFYDHGRKGATVRQVSNVVAATDVTLLALAGIGLRYNKKLGFASCKRNAGATEGINVLMEKKNFDGKWEYGISCIEYTEFDKFDISNRSPSSNGLQADFPANTNILYVDLHSAELIGSSSNAKSLPNMVLNTKKRIEYLDQYGDYHSVMGGRLECTMQNIADNFFNKFPSRCHGSLEDKLDTYIVYNERRKVTSSAKKKKPHASAALHQTPDGALLDILRNGYDLLTECDIKLPMIEANDKYVDSPPPYLILLHPALGPLWEVSRQKFKGGSISSCSELQLEIAEFSWNNVQVDGSLIVTAENAMGSTTPNDNGEPILQYGLRCGKCKLHNVNVVNRGIDWNSKSNVYWRNDVNRLETCKIILHGNAEFEASNVTIEGHHVFEVPDGHKLKITSGNAGLSINLEALKEEVMETGSWYWNYQLNGSHIHLQQVEVSQS
What is the function of this protein?
Involved in the biosynthesis of sulfolipids in the chloroplast.  Catalyzes the first committed step in sulfolipid biosynthesis.  Converts glucose 1-phosphate to UDP-glucose, the precursor of the polar head of sulfolipid.  In addition to glucose 1-phosphate, can use galactose 1-phosphate, but with much lower activity.  No uridyltransferase activity with other hexose monophosphates.  Specific for UTP and cannot use ATP, CTP, and GTP.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase 3, chloroplastic, UDP-glucose pyrophosphorylase 3.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LRC55_RAT
Sequence: MGDTWAQLPWPGPPHSALLLVFFLLAAGVMHSDAGASCPVLCTCRNQVVDCSNQRLFSVPPDLPMDTRNLSLAHNRIAAVPPGYLTCYMELRVLDLRNNSLMELPPGLFLHAKRLAHLDLSYNNLSHVPADMFREAHGLVHIDLSHNPWLRRVHPQAFQGLVHLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLGITANCCHRWSKANEEEEI
What is the function of this protein?
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha).  Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 55, BK channel auxiliary gamma subunit LRRC55.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TGS3_MYCTU
Sequence: MVTRLSASDASFYQLENTATPMYVGLLLILRRPRAGLSYEALLETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSALPSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQALINGVTALAIGHVIADRTRRPPAFPEDIWVPERDPGTTRLLLRAVGDWLVRPGAQLQAVGSAVAGLVTNSGQLVETGRKVLDIARTVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYDCDSTTWC
What is the function of this protein?
Upon expression in E. coli functions as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA.  Has no wax synthase activity to produce wax esters.
What are the official names of this protein?
Probable diacyglycerol O-acyltransferase tgs3, TGS3, Probable triacylglycerol synthase tgs3.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: GPH_HAEIN
Sequence: MNTQFKLIGFDLDGTLVNSLPDLALSVNSALAEFNLPQAPEELVLTWIGNGAPVLIARALDWAKKQTGKVLTETEVKQVTERFNFYYGENLCNVSRLYPNVKETLEILKEKGYVLAVVTNKPTRHVQPVLAAFGIDHLFSEMLGGQSLPAIKPHPAPLYYLCGKFGFEPRQVLFVGDSKNDIIAGHAAGCAVVGLTYGYNYNIPIRESNPDWVFDDFAQLLSIL
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: HSP83_LEIIN
Sequence: MTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRLCIRVVPDKENKTLTVEDNGIGMTKADLVNNLGTIARSGTKAFMEALEAGGDMSMIGQFGVGFYSAYLVADRVTVTSKNNSDESYVWESSACGTFTITSTPESDMKRGTRITLHLKEDQMEYLEPRRLKELIKKHSEFIGYDIELMVEKTTEKEVTDEDEEDTKKADEDEEPKVEEVREGDEGEKKKTKKVKEVTKEYEVQNKHKPLWTRDPKDVTKEEYAAFYKAISNDWEDPRATKHFSVEGQLEFRSIMFVPKRAPFDMFEPNKKRNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIRKNIVKKCLEMFDEVAENKEDYKQFYEQFGKNIKLGIHQDTANRKKLMEFVRFYSSESGEEMTTLKDYVTRMKAGQKSIYYITGDSKKKLESSPFIEQAKRRGLEVLFMTEPIDEYVMQQVKDFEDKKFACLTKEGVHFEESEEEKQQREEEKAACEKLCKTMKEVLGDKVEKVIVSECLSTSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRRVDADENDKAVKDLVFLLFDTSLLTSGFQLEDPTGYAERINRMIKLGLSLDEEEEVVAAEATVAETAPAEVTAGTSSMEQVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 83-1, HSP 83.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ALISL
Sequence: MSLNAETKAAIVAEYAQCENDTGSPEVQVALLTASINHLQGHFANHKHDHHSRRGLLRMVSSRRKLLDYLKGKNSTRYQDLIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PAT_SHIFL
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGVFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: DEF75_ARATH
Sequence: MAKIKSLDVITVAIILLLVIADQATAITVQADCIGPCNDDCQQLCKSKGYTDWTCASFRTKSSCCCKPPRHQIFEQNAQLNN
What are the official names of this protein?
Defensin-like protein 75, Low-molecular-weight cysteine-rich protein 45, Protein LCR45.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRB_IDILO
Sequence: MAKKFELVSKYKPAGDQPKAIESLLDNLDAGLAHQVLLGVTGSGKTFTMANVIERSQRPTLILAHNKTLAAQLYGEMKEYFPNNAVEYFVSYYDYYQPEAYVPTTDTFIEKDASINDHIEQMRLSATKALMERRDVVLVASVSAIYGLGDPESYMKMMLHLRRGDIIDQRDVLRRLAQLQYKRNDAAFERGTYRVRGDVIDIFPAESEEIAVRLELFDSEVDRISFFEPLTGQITEKDVARATIYPKTHYVTPREVLVKAIEKIKDELKDRRDILLKQNKLIEEQRINQRTQFDIEMMLELGYCSGIENYSRYLSGRAPGEPPPTLMDYLPDNALLIIDESHVTVSQIGAMYKGDRSRKENLVEYGFRLPSALDNRPLKFDEFEAIAPQTLYVSATPGKYELERSGNEVVEQVVRPTGLIDPQIEVRPVATQVDDLMSEIRLRTEVGERVLATTLTKKMSEDLADYLDEHGIKVRYLHSDIDTVERMEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSDRSLIQTIGRAARNVNGRAILYADRITGSMQRAMDETDRRREKQIAYNKEHGITPQGLNKDITDVMDLGQGSAKARKSKAEKALAEVASGYDARTVVVKDAKAVMKEIDAKEKEMYKAAQNLEFEQAGKLRDEVAELREQLKRAV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMD4_CAEEL
Sequence: MKLIRKYHMIPYENGSEYESAKRFLENILSASDVDPTTKCRFYQDVLYRIRNHPELPIVTEELFDVVQENLQQQNDNQKRNVKLERRNLKYEVIPEKRESYQEKDYTNPPVYKAENEQLFDDVPYRNDGINHLKPRKNVYIKEEPEDEDYHMEYEKIPEINMEQNVNELFTEPQKHAAGKIKKSKNQKKDGTLSRPLGKKENKSVVKVKIEEPDQDMQAAPPRKPEEKNEETAPVSIKKRSFQQDATSNKRQKFDLKRGKSMNNVKPRKLYKMQLDEEDEDEEPMVDETPQNTEISIKKRPFQQDSTKNLNKRQKFDLKRRKNMSRVRPNKIYKMQNLKRNISSTIPDNGTNIPAAKRRVLRGSGSAPPPGSRVYCRLWKF
What are the official names of this protein?
Uncharacterized protein F54H12.4.
Protein: MOBA_ACISJ
Sequence: MIDTHDITGLILAGGRGSRMGGVDKGLQNFRGLPLALHTLMRLQPQVGDVMINANRNLAAYESFGVPVWPDGLADYAGPLAGFLTGLERCETPWLLTVPCDTPLFPPDLAARLAQAAMREGADIAMAAAPEADERDGTVRVRTQPVFCLLRVTLLESLVRFTQGGGRKIDRWTEQHACAVVPFDQPGDDPHAFYNANTLAELHALEGLGLR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGT10_PANGI
Sequence: MKSELIFLPVPAFGHLVGMVEMAKLFISRHENLSVTVLISKFFIDTGIDNYNKSLLAKPTPRLTIINLPEIDPQKYLLKPRCAIFPSLIENQKTHVRDVMSRMTQSESTRVVGLLADILFVDIFDIADEFNVPTYVYSPAGAGFLGLAFHLQTLNDDKKQDVTEFRNSDTELLVPSFANPVPAEFLPSIFLEKDGRHDVLLSLYWRCREAKGIIVNTFEELEPYAINSLRMDSMIPPIYPVGPILNLNGEGQNSDEAAVILGWLDDQPPSSVVFLCFGSFGSFPENQVKEIAMGLERSGHRFLWSLRPCISEGETTLQLKYSNLELPAGFLDRTSCVGKVIGWAPQMAILAHEAVGGFVSHCGWNSVLESVWYGMPVATWPMYGEQQLNAFEMVKELGLAVEIEVDYRNEYNKSDFIVKADEIETKIKKLMMDGKNSKIRKKVKEMKEKSRVAMSENGSSYTSLAKLFEEIM
What is the function of this protein?
Component of the dammarane-type triterpene saponins (e. g.  PPT-type ginsenosides or panaxosides) biosynthetic pathway (PubMed:26032089, PubMed:27746309, PubMed:29378087).  Glycosyltransferase that catalyzes the biosynthesis of ginsenoside Rh1 from protopanaxatriol (PPT) and the conversion of ginsenoside F1 to ginsenoside Rg1 (PubMed:26032089, PubMed:27746309).
What are the official names of this protein?
UDP-glycosyltransferase 100, UGTPg100.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: LIPA_SHEPW
Sequence: MNRPERLQPGVKLRDADKVSRIPVKVVPSERDTMLRKPDWLRVKLPASNQRITEIKQALRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPKKLAQTIKDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRLLNPEIKIETLVPDFRGRIDKALDILAIEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKKFKERHPDIPTKSGLMMGLGESNEEIAQVLHDLRAHDVEMLTLGQYLQPSKFHLPVERYVSPAEFDELKDLAESIGFTHAACGPLVRSSYHADLQAQGKEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_AGRFC
Sequence: MMTDARTTAEGGMETSYGFHKVDEGKKQGLVNEVFHKVAKRYDIMNDVMSAGLHRLWKDAMVSALSPRKDPSYKILDVAGGTGDVAFRIIEASNRLAHATVLDINGSMLAVGEERAAKKKLSDNLTFVEANAEELPFEANTFDAYTVAFGIRNVPRIDVALKEAYRVLKRGGRLLVLEFSEVDMPLLDRVYDAWSFNAIPQFGKMITGDAEPYQYLVESIRKFPNQEDFATMIRTAGFSRVTYTNYTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: YN11B_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYQQQCMMTQNQANPSGWSFYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPTWVKDILSADYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLRYARHRYIHMTVADLFSDIHSMYEEQQESKRNKSTYRRNPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTSNNSSGPDNDLIRGSTTEPIQLKNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPGINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISKSNILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQYNTHESSHTSKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTKLSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDRYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIEKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-NL1 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VPS5_YEAST
Sequence: MDYEDNLEAPVWDELNHEGDKTQSLVSNSIESIGQISTNEERKDNELLETTASFADKIDLDSAPEWKDPGLSVAGNPQLEEHDNSKADDLINSLAPEQDPIADLKNSTTQFIATRESGGALFTGNANSPLVFDDTIYDANTSPNTSKSISGRRSGKPRILFDSARAQRNSKRNHSLKAKRTTASDDTIKTPFTDPLKKAEKENEFVEEPLDDRNERRENNEGKFTASVEKNILEQVDRPLYNLPQTGANISSPAEVEENSEKFGKTKIGSKVPPTEKAVAFKVEVKDPVKVGELTSIHVEYTVISESSLLELKYAQVSRRYRDFRWLYRQLQNNHWGKVIPPPPEKQSVGSFKENFIENRRFQMESMLKKICQDPVLQKDKDFLLFLTSDDFSSESKKRAFLTGSGAINDSNDLSEVRISEIQLLGAEDAAEVLKNGGIDAESHKGFMSISFSSLPKYNEADEFFIEKKQKIDELEDNLKKLSKSLEMVDTSRNTLAASTEEFSSMVETLASLNVSEPNSELLNNFADVHKSIKSSLERSSLQETLTMGVMLDDYIRSLASVKAIFNQRSKLGYFLVVIENDMNKKHSQLGKLGQNIHSEKFREMRKEFQTLERRYNLTKKQWQAVGDKIKDEFQGFSTDKIREFRNGMEISLEAAIESQKECIELWETFYQTNL
What is the function of this protein?
Plays a role in vesicular protein sorting.  Required for retention of late Golgi membrane proteins and vacuolar biogenesis.  Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.  The VPS5-VPS17 subcomplex may assemble onto the membrane to promote vesicle formation.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 5, Carboxypeptidase Y-deficient protein 10, Vacuolar protein-targeting protein 5.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LDH_STRPC
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.