PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_BACSU
Sequence: MNTLTVKDIKDRLQEVKDAQDPFIAQCENDPRKSVQTLVEQWLKKQAKEKALKEQWVNMTSYERLARNKGFRLIAGVDEVGRGPLAGPVVASAVILPEECEILGLTDSKKLSEKKREEYYELIMKEALAVGIGIVEATVIDEINIYEASKMAMVKAIQDLSDTPDYLLVDAMTLPLDTAQASIIKGDAKSVSIAAGACIAKVTRDRMMSAYAETYPMYGFEKNKGYGTKEHLEALAAYGPTELHRKTFAPVQSFR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC_BOVIN
Sequence: MVGYDPKADDRDISNVEVAVAGSVSGLVTRVLISPLDVIKIRFQLQIERLSRSDPNAKYHGILQAGRQILQEEGPTAFWKGHIPAQLLSIGYGAVQFLSFEALTELVHRASVRDARDFSVHFLCGGLSACVATLAVHPVDVLRTRFAAQGEPRVYKTLRDAVVTMYRTEGPLVFYKGLNPTLIAIFPYAGFQFSIYSSLKRAYEWALPAEGKKNGNFKNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEQARASFGQVRSYKGLLDCAGQVLREEGAQGCFKGLSPSLLKAALSTGLVFFWYELFCNFFHHMRKADS
What is the function of this protein?
Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria.  It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier, Solute carrier family 25 member 19.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL3_ACAM1
Sequence: MSVGILGTKLGMTQVFDEAGRAIPVTVVQAGPCPVTQIKTAQTDGYTAIQIGYGSTTEKALTRPELGHLKKSGSTPVRHLQEYRLADVSEYELGQSISADLFSEGQLVDISGTSIGRGFAGYQKRHNFRRGPMGHGSKNHRAPGSTGAGTTPGRIYPGKRMAGQMGNVKKTIRKLTVVRVDAERNVLLIKGSVPGKPGALLNIQPATIVGES
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CYB_NYCVZ
Sequence: MTNIRKTHPLFKIINDSLIDLPAPSSISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTTTAFQSVTHICRDVNYGWILRYLHANGASMFFICLFLHVGRGLYYGSYTYKETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDMLGALAMILILLTLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPYIIIGQLASILYFLLILVLMPLVSIAENHFLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS17E_METAC
Sequence: MGNIRETNIKRTAFSLLENYGDVFTKDFETNKALVTKYTTIESKIIRNRVAGYVTRKVARMKVY
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: PUR7_XANCB
Sequence: MPVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAERGILLADTKFEFGTDADGRLYIMDEMLTPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPRLPADVIERTRAKYAEALQRLAGISVD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SPP3A_ARATH
Sequence: MDRLEGPPRLILVADLDCTLVDHDDPENNDLLRFNALWEAHYRHDSLLVYCTGRSFSSYSSLRKKRPLLTPDIAVTSVGSEIVYGGGESTVSDVVWTARLDYKWNRDIVVEETLKFPKLEPQPDKSQEEHKVSFFVGREDAVEIMKVLPGILEERGVDVKLVYSNGYAFDVLPRGAGKQGALTYLLDKLDIEGKQPSNTLVCGDSGNDAELFNISDVYGVMVSNSHEELLQWYEENAKDNPKIFHASERCGAGMIEAIQRFNLGPNVSPRDVMDTENFHGESLNPAHEVVQFYLFYERWRCGEVEKSDKYLQNLKSLSSPLGIFVHPSGVEKPIHEWIDEMENLYGDGKEKKFRIWLDNVTSSHISSDTWLAKFVKHELSEGKVRSCSTKVLLSYKEEKQRLTWMHIHQSWLDESSSDDQEKWIF
What is the function of this protein?
Catalyzes the final step of sucrose synthesis.
What are the official names of this protein?
Probable sucrose-phosphatase 3a, AtSPP3a.
What is the protein family that this protein belongs to?
Belongs to the sucrose phosphatase family.
Protein: GLNA_CANLF
Sequence: MATSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKGVEELPEWNFDGSSTFQSEGSNSDMYLVPAAMFRDPFRKDPNKLVFCEVFKYNRKPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKIAGTNAEVMPAQWEFQIGPCEGIDMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEESIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity).  Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity).  Essential for proliferation of fetal skin fibroblasts.  Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation.  May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity).  Plays a role in ribosomal 40S subunit biogenesis (By similarity).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane.
Protein: MATK_CARAN
Sequence: MEKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFLENADYDKKYSSLIVKRLILRMYEQNRLIIPTKDLNQNNFLGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFEGNLFKKSYNLQSIHSIFPFLEDKLSHFNYVLDVVIPYPIHLEILVQTLRYRVKDASSLHFLRFCVYEYFNCKNFYIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSTSYEVLFERIFFYGKIQHFFKVFVNNFPAILGLLKDPFIHYVRYHGRSILATKDTPLLMNKWKYYFVNLWQCYFSVWFQSQKVHIKQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKVIWTHSSDSDILNRFVRICRNISHYYSGSSKKKFLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPISYYASKRLYRVRIWYLDILYLNDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GRAA_MOUSE
Sequence: MRNASGPRGPSLATLLFLLLIPEGGCERIIGGDTVVPHSRPYMALLKLSSNTICAGALIEKNWVLTAAHCNVGKRSKFILGAHSINKEPEQQILTVKKAFPYPCYDEYTREGDLQLVRLKKKATVNRNVAILHLPKKGDDVKPGTRCRVAGWGRFGNKSAPSETLREVNITVIDRKICNDEKHYNFHPVIGLNMICAGDLRGGKDSCNGDSGSPLLCDGILRGITSFGGEKCGDRRWPGVYTFLSDKHLNWIKKIMKGSV
What is the function of this protein?
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse.  It cleaves after Lys or Arg.  Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity.  Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
What are the official names of this protein?
Granzyme A, Autocrine thymic lymphoma granzyme-like serine protease, CTLA-3, Fragmentin-1, T cell-specific serine protease 1, TSP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Delivered into the target cell by perforin.
Protein: MUTL_GEOTN
Sequence: MGRIHKLDDQLANKIAAGEVVERPASVVKELVENAIDAHSTAVEIELEEAGMTKIRVIDNGDGMEEEDCLLAFERHATSKIQDEHDLFRIRTLGFRGEALPSIASVSEVELVTSTGSGPGTKLVLKGGALVARERAAGRKGTDITVSNLFFNTPARLKYMKTIHTELGHAADVVNRLALAHPDVSFRLRHHGKTLLATNGSGDVRHVLAAIYGMETAKQMIPIEAESLDFTVRGYISLPEVTRASRNYMSLIVNGRYVRNIPLMKAIEAGYHTLLPIGRYPIVFLAIEMDPVLVDVNVHPAKLEVRFSKEAELNELITATIRQAFRQRTLIPSVSADSKTVKAKAEQASWTFAHRVHEPPAQPDGKAEGTSDVTAAASLASEGSLSPLPAAAQADAPAVSEEAEASVFSERRTGVVNDLPAAELKRDAEVEEEPTEACLPADEQAEEKRAVDRLPPLYPIGQLHGTYILAENEHGLYMIDQHAAQERINYEYFREKLGEVTNEVQELLVPLTFEYPADEYERIAACRDELARCGVFLEPFGPRAFLVRSHPVWFPKGKEKEIIEEMIEHVLTAKTVDIKQLREQAAIVMSCKRAIKANQHLRTDEIFALLETLRQTTDPFTCPHGRPIIVHFSTYEIEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DCVR_ORYSJ
Sequence: MAALLLSSHLTAASSSSTTSPTARPAPSFVSFRAANAAPKGARRGWPFLASSVEPPPAASAAQPFRSLAPSETTVLVTGATGYIGRYVVRELLRRGHPVVAVARPRSGLRGRNGPDEVVADLAPARVVFSDVTDAGALRADLSPHGPIHAAVCCLASRGGGVRDSWRVDYRATLHTLQAARGLGAAHFVLLSAVCVQKPLLEFQRAKLRFEGELAAEASRDPSFTYSIVRPTAFFKSLGGQVETVKNGQPYVMFGDGKLCACKPISEEDLAAFIADCISDEGKANKILPIGGPGKALTPLEQGEMLFRLLGREPRFIKVPIQVMDAAIWVLDALAKVFPGVEDAAEFGKIGRYYASESMLVLDPDTGEYSDEMTPSYGSDTLEQFFERVIREGMAGQELGEQTIF
What is the function of this protein?
Catalyzes the conversion of divinyl chlorophyllide to monovinyl chlorophyllide.  Reduces the 8-vinyl group of the tetrapyrrole to an ethyl group using NADPH as the reductant.  Can use (3,8-divinyl)-chlorophyllide a (DV-Chlidea) > (3,8-divinyl)-chlorophyll a (DV-Chla) > (3,8-divinyl)-protochlorophyllide a (DV-Pchlidea) > (3,8-divinyl)-magnesium-protoporphyrin IX monomethyl ester (DV-MPE) > (3,8-divinyl)-magnesium-protoporphyrin IX (DV-Mg-Proto) as substrates.
What are the official names of this protein?
Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRT1B_ONCMY
Sequence: MPRRRRASRRIRRRRRPRVSRRRRRGGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-1B.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BTR_BACSU
Sequence: MQNAVIYQPVQIEYLKKTSDLFSEQQLADSFVLIFHLKGNGYISIGTNTNPLQKKTLYVCPPNETFGFTPAADGHIDACIIRLLSYIKETGQDIFTPCTESELAKLKLMNVSHIENLAVRLQELAALWNESSQLSQLKCVIEVQSLIYDLFTASLSDQTDTHSAIEKTKHYIETHADTKITLAQLSQMAGISAKHYSESFKKWTGQSVTEFITKTRITKAKRLMAKSNCKLKEIAHQTGYQDEFYFSRIFKKYTGCSPTSYMKKRRKKIAAYGRGTMGHLIPLHHIPFAAALHPKWTSYYYQHYSTDIPVQLSAYRFNEKWEENLYTLSQAEPDVIVSMDSISPEEQDRLNRIAEVMYLPSEESWRTHFLQTASFLKEESEAEKWLADYDQQTTAAKKTLQHVQGLRFLFLRLHKQNFYLAHNRSVREVFFGDLGFSSATTADTPSEQAISLENIANYQADCMMLFLFKEPETIAYYQQLQQTEAWQNLSAVRDNRVYLLSLDPWNEYSACGHERIVQQTVSLLSGDCP
What is the function of this protein?
In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system.  Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter.  Activity is increased in the presence of bacillibactin.
What are the official names of this protein?
HTH-type transcriptional activator Btr, Bacillibactin transport regulator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_BRUMB
Sequence: MSNPRHNEREVRSPRGDELNAKSWLTEAPLRMLMNNLDPDVAERPHELVVYGGIGRAARTWDDFDRIVATLKTLNDDETLLVQSGKPVGVFRTHKDAPRVLIANSNLVPHWANWDHFNELDKKGLAMYGQMTAGSWIYIGAQGIVQGTYETFVEAGRQHYGGNLKGRWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHSLDEALAKIDAWTKAGEAKSIALIGNAAEIFPELVKRGVKPDIVTDQTSAHDPVHGYLPLGWTVAEWRAKQENDPKAVEKAARASMKVQVQAMLDFWNAGIPTVDYGNNIRQMALEEGLENAFAFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIAKTDAKVKELLPDNKHLHNWLDMAKERIAFQGLPARICWVGLGDRHRLGLAFNEMVRNGELKAPIVIGRDHLDSGSVASPNRKTEAMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVICCDGTEDADRRLERVLWNDPATGVMRHADAGYDIALDWARKQGLRLPAILGN
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP2_COCP7
Sequence: MAGSNTLSSSEHGDDPRGHSYSIHIQTRGTTLDKYPAKQHARNVARQLGLTDGLIYLMSQSTRTLEDSDQPQPFRQRRYFFYLSGVDEPDCHLTFDIKSDILTLYVPHYDLRKAIWVGPTLRPSEAMMRYDLNAAKTYDELSKNIRTWASKRMSPVIYILHEGQKPNINAHFLAFNHEDLLPAMDACREIKDEHEIDLIRRANEISASAHIEVLLGIRNMQNEAEIHGKFLDTCVSQGARNQSYEIIAASGENAAILHYTKNNEPLDDRQLVCLDAGAEWNCYASDVTRTFPRRPYWPSCESANIYSVVQRMQEECINGLKEGVRYLDLHILAHRIAIEELLSLGILKGGSTEEILQSGASLVFFPHGLGHHVGLEVHDVSPTPLMAFSLDKYKGLPLLSCRPPCTLSAPYLKAGMVVTVEPGIYFSRPALKDARRKPLSKYIDMDVVQKYIPVGGVRIEDDILVTRDGFENLTKAPKGREMLKTIR
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase CPC735_009100, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: CDK1_ORYJA
Sequence: MEDYVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKHPNVVRLLDVLMQESRLYLIFEFLSMDLKKYLDSIPSGQYMDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLWYRAPEVLLGSPRYSTPVDVWSTGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNDVWPDVESLPDYKNTFPKWMEGSLSSMVKNLDKNGLDLLAKMLIYNPPKRISAREAMTHPYFDDLDKSTLPAACINGV
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins.  Required in higher cells for entry into S-phase and mitosis.  May play a role in regulating the amplitude of the cyclic expression of circadian clock genes.
What are the official names of this protein?
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GRPE_PROMP
Sequence: MIEKQSDNVENLEDNVSQEVNKNEDSSVIENQTSEDKQTLEVDDENIYAEDLKNTITNNDARLEQLEKEHETLKSQYVRIAADFDNFRKRQSRDQDDLKVQLVSKALTAILPIVDNFERARQQLKPESEEAQTLHRSYQGLYKQLVEVLKQQGVSPMRVVAQQFDPKLHEAVLREPSQEFNEDIIIEELQRGYHLEGKVLRHALVKVSMGPGQQNSQEPEEKDKVEEDIDSENPISEEN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS27_HORVU
Sequence: MVLQNDIDLLNPPAELEKLKHKKKRLVQSPNSFFMDVKCQGCFNITTVFSHSQTVVVCPGCQTVLCQPTGGKARLTEGCSFRRKGD
What are the official names of this protein?
40S ribosomal protein S27, Manganese efficiency-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: TGT_BUCAI
Sequence: MNFKVLYQDNNARCGVFNFNQEIIETPVFMPVGTYGAVKSISTEEIKNTGSRIILSNAFHLYFRPGLEIIKLHGNLHNFMNWSGPILTDSGGFQVFSLSRFCKVNEEGVIFQNHIDGKKTFLTPKISMKIQSDLGSNIVMIFDQCIEYNQNWEKTKNAMERSLYWAKKSRIYFDSYKNKNSLFGIIHGGIYPSLRDISLQELIKIDFDGYALGGLAVGEPKIEMYKLLDHICPQIPKNKPRYLMGVGKPEDLIEGVRRGVDMFDCVIPTRNARNGHLFVTNGVIKIRNKKYKKDLSCLDNTCVCYTCRYYSRSYLHHLDACNEILGARLNTIHNLHYYQTLMSNIRNSIKNNTFEQFSVNFYKQKNKIDF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: HSDD2_ARATH
Sequence: MSPAATETERWCVVTGGRGFAARHLVEMLVRYEMFCVRIADLAPAIMLDPQEGNGVLDEGLRSGRVQYISADLRDKSQVVKAFQGAEVVFHMAAPDSSINNHQLQYSVNVQGTQNVIDACVDVGVKRLIYTSSPSVVFDGVHGILNGTESMAYPIKHNDSYSATKAEGEELIMKANGRNGLLTCCIRPSSIFGPGDRLLVPSLVAAARAGKSKFIIGDGNNLYDFTYVENVAHAHVCAERALASGGDVSTKAAGQAYFITNMEPIKFWEFMSQLLDGLGYERPSIKIPAFIMMPIAHLVELTYKVLGPYGMTVPQLTPSRVRLLSCSRTFDSTKAKDRLGYAPVVPLQEGIRRTIDSFSHLTAGSQSKREGPSKASRILGGGKVADTLLWKDLKQTLIAIFILISIYYNFVATGSTVVTALSKALLVASVFLFLHGILPEKIFGYTVEKIPASQFHLSKDSSHDLSLSVISSWNTTVKALRSLCQGNDWSFFFKVVFVLLALSLAGAISLHSIFVIGLPIAFLAFLVYEKKEQEIDSIVVSFKSFACKHKSDVYEKLFGSKKHD
What is the function of this protein?
3beta-hydroxysteroid-dehydrogenase/decarboxylase involved in sterol synthesis (PubMed:16835224).  Catalyzes the formation of 3-oxosteroids from 3beta-hydroxysteroids-4alpha-carboxylate (PubMed:16835224).  Involved in the regulation of inflorescence internodes and leaves growth, probably by affecting auxin transporter activity possibly by altering sterol composition in the membranes (PubMed:22673766).
What are the official names of this protein?
3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2, At3BETAHSD/D2, 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase isoform 1-2, Reticulon-like protein B19, AtRTNLB19, Sterol-4-alpha-carboxylate 3-dehydrogenase 2, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SWP7_ENCCU
Sequence: MFLMTSTPLLLVIGLVREGLALASEYNFGGFEADPACTKDDKIYLVSMYAHFDRGTIDAIFSAFSDCKDEREAVEHYLKSRVIGPYNDYLSKFKVKIGFDAKDYDVNELVPTKRFDSSCELVEPVGTRTSAVHNHLLNTYKDRKIGIHLFLWSCPTHNENIMDKIVIGEPKECARSIGVLWRGTEETIDFIKSGISEAISGAKDLFLNQGFPSPRDEDKLSYVCQHVDTCIASKPSVNGAIIFGIDETSDDAISTHIDVDTHPSDVYIPPQRGARAQRVIYVNEPSDSVDDECKY
What are the official names of this protein?
Spore wall protein 7.
What is the protein family that this protein belongs to?
Belongs to the SWP7 family.
What are the subcellular locations of this protein?
Spore wall.
Protein: SYV_LACLA
Sequence: MTNELTPKFNPTEVEAGRYEKWLEADVFKPSGNPDAEPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVAARLAEDGILPQDLGREKFLDKVWEWKDEYATTIKEQWGKMGISVDYSRERFTLDEGLSQAVRKVFVQLYNKGWIYRGEKLINWDPKAMTALSDIEVIHKEIDGAFYHITYQIEGSDEFVEIATTRPETFLGDTAVIVNEKDERYKHLVGKNVILPIINRVIPILTDDHADMEKGTGVVKITPAHDPNDFEVAMRHDLPMINMMNNDGTINENGGKYEGLDRFEARKQIVADLKELGQLVDIKPVRHEVGHSERTGVVVEPRLSTQWFVKMDELAKNAIANQTTEDAVEFYPPRFNDTFMQWMENVHDWVISRQLWWGHQIPAWYNEAGEMYVGEEAPEGEGWTQDEDVLDTWFSSALWPFSTMGWPDENSADFIRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGKSPFHNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYDKMDAAWNFINKIWNVSRYILMNAEDISADAVSSALTKVANKTAGNVTDRWILTRLNDTVERVTEQMDKFEFGVAGHILYNFIWDEFANWYLELTKEVMFGEDEAEKDITRAVLLHVLDQVLRLLHPIMPFFTEEIFEKLPNTSGSIVVAEYPKVRPEFNDDKASEGVAMLIELITAVRNIRAEVNTPLSKAVPMLIKSEHADFLNAVSPYISRFTNPSELTIAKDLAVPEQAMSAVITGAELYLPLAGLINIEEEIARLEKELAKWQKELDLVNKKLGNERFVANAKAEVVQKEKDKLADYQEKFDTVKARIAELKEN
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB_BURMA
Sequence: MTGTTLAATYGPISGADLEAELAQPRIADGDAQDAAVYERDGGARALPFASGGAPPDGDRADVRRAAGAGDASVRLTRVSKRYGERAVLADVDLSIGRGSFVSIVGRSGCGKSTLLRLVAELETPSAGTLVKRGDGGGALDTRIMYQEARLLPWKTVLQNVMLGLGRRAKDDARAVLDEVGLLARANDWPAQLSGGQRQRVALARALVHRPQLLLLDEPLGALDALTRIEMHALIERLWREHRFTALLVTHDVQEAVALADRVLLIEAGRIAFDQRVPLDRPRARASAAFAALEDRVLQRVLTGSDAAPAAPNAAGPEGASRGRAAPASGLRWAV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOE_PEDPA
Sequence: MELENFKGQNKNELSMIEVAHAILAKSGEPMAFVDLANAVQSYLDKTDEEFRNRLSQFYTDLNVDGSFISLGENTWGLRTWYPFESIDEALIHAEDEDEDRPVRKKRKKVNAFLADAADDDDVIDYDSDDPEDEEVEAEDTTSDDAPAFEDLSNDDDTDVLPDGIEGQLSELNEDDEN
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.