PharMolix/UniProtQA huggingface dataset:
Protein: NDH2_SCHPO
Sequence: MSVSKARLQSVVRLSRTVPYSKTMVRSFHVSCAVKNSGNVPTPRNKSFFSRALEMAEVTSSLSMLGAVALFQSLRRLNNSSPKGKSGVPKKNIVVLGSGWGAVAAIKNLDPSLYNITLVSPRDHFLFTPMLPSCTVGTLRLPSITEPIVALFKGKIDPSNIHQAECTAIDTSAKKVTIRGTTEANEGKEAVIPYDTLVFAIGAGNQTFGIQGVRDHGCFLKEAGDAKKVFNRIFEILEQVRFNKDLSPEERARLLHITVVGGGPTGMEFAAEMQDFIDNDVKDMFPELQKDIHVTLIEAAPGVLPMFTKSLITYTENLFKNLNIKIMTKTVVKDVNEKNLIVQKTNPDGSKAMQEIPYGMLVWAAGITARPLTRTLMSSIPEQSGARKGLIVDEFFRVKGVPEMYAVGDCAFSGLPATAQVANQQGAWLAKNLNVEGKKFALHERIQALEKQLGEKEAPSQVAGLKQQVEQLKLEPFKYHHQGALAYVGDEKAIADLKLPFMKKMLPLQGIVGHTFWRLAYLNELISARSQFMVLIDWLKTRLFGRYDAKV
What is the function of this protein?
Catalyzes the oxidation of NADH.
What are the official names of this protein?
Probable NADH-ubiquinone oxidoreductase C947.15c, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: IF2_COREF
Sequence: MPGKLRVHELAKKLGITSKELLATLKEQGEFVKTASSTIEPPVVKKMQEHYQATGGAKPDTDNKPTPAKPAAKPGAPAPKPGTAQKPTAPTPGAVAAPKPGTAAAKPTPAKPAAPKPTAAKPAPAKPTAPKPATPAFSGPTPGDAAKKAAEDKATPKPGGEAPRPNAMPRPMAKPGPKPGARAPRVANNPFSTGAADRPGPRPGGGGPRPGGGPRPGGAPRPQGGQRSGAPRDGQGGPRGQRPGPGSGGPRPQGGNAAGAASQERQGGGRRPSPAMMPPTPGQMPAKAPGKGGRGGGQGGPGGGSGGFNRGGGGGAGRGGRRGGTAGAFGRPGGAPRRGRKSKRQKRNEYESMQAPNVIGGVRLPDGRGQTLRLARGASLSDFADKIGADAAALVQALFNLGEMVTATASVSDETLMLLGDEMNFKVEVVSPEDEDRELLESFDLQFGEDIGDEQDLAKRPPVVTVMGHVDHGKTRLLDTIRKANVGSGEAGGITQGIGAYQVKVEVEDDLRTITFLDTPGHEAFTAMRARGAKSTDIAVLVVAADDGVMPQTIEAINHAKAADVPIVVAVNKIDKPDASPEKIRGQLTEYGLVPEEYGGDTIFVDISAKQGTNIDELLASVCLTADAELDLVANPDMDAQGVAIEAHLDRGRGPVATVIVQRGTLRVGDSIVVGDTYGRVRRMVDEYGRDVDEAGPSRPVQVQGLNGVPGAGDNLLVVEDDRIARQIANQRNARKRNALAARSRKRVSLEDLDSVLKETSVLNLILKGDNAGSVEALEEALLKIEMDDEVELNIIDRGVGAVTQTNVTLAAASNAVIIAFNVRAEGKATEEANAEGVDIRYYTIIYRAIEEVEAALKGMLKPIYEEREVGKAEIRAIFKASAIGLIAGCMVEEGKVRRNATARIIRDGNVIASNAKIESLRREKDDVTEVSAGYECGMVLSYPDIAVGDKIEVFEMVEVPRDS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_MONPV
Sequence: MIFFMFNMNINSPVRFVKETNRAKSPTRQSPGAAGYDLYSAYDYTIPPGERQLIKTDISMSMPKFCYGRIAPRSGLSLKGIDIGGGVIDEDYRGSIGVILINNGKCTFNVNTGDRIAQLIYQRIYYPELEEVQSLDSTDRGDQGFGSTGLR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: COX3_CANLF
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHYNSMALLTLGFTTNLLTMYQWWRDVIREGTFQGHHTPIVQKGLRYGMVLFIVSEVFFFAGFFWAFYHSSLAPTPELGGCWPPTGIIPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRKHMLQALFITISLGVYFTLLQASEYYETSFTISDGVYGSTFFMATGFHGLHVIIGSTFLIVCFLRQLYYHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBZ_ADICA
Sequence: MTTAFQFALFALIATSFLLVVGVPVAFASPGGWSDNKNIVFSGASLWIGLVFLVGIPNSFIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: TAGH_ALKCK
Sequence: MNPKMILTGVSKKYTLYRNNTEKLKAMFFPKTREQHRDFYALKDINLEVYEGETIGVIGINGSGKSTISNILASVIPPTEGEMTVNGETSLIAINVGLNKNLNGYENIEQKCLMHGFSKKEIEELMPAIEEFADIGDFIDQPVKSYSSGMKSRLGFAISAHTNPDILIVDEALSVGDKTFYQKCKDKIDEFKAQNKTIVFISHNIKEIKNLSDRVLWLHNGEVREFGDKNEVIKQYEDYINWFNKLSKEEKEAHKQELKEMRSLAPSLYEEQENGKAGSGGDGTQPIVQPKRDKQAVKSAVWFFSQLVVFAVIFLTAAYFLVVPQLTDGSGSEELEQVAVGAEVQAGTSMGDIDNSDVSL
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RIBB_HELPY
Sequence: MILKRVTEALEAYKNGEMLIVMDDEDRENEGDLVLAGIFSTPEKINFMATHARGLICVSLTKDLAKKFELPPMVSVNDSNHETAFTVSIDAKEARTGISAFERHLTIELLCKDTTKPSDFVRPGHIFPLIAKDGGVLARTGHTEASVDLCKLAGLKPVSVICEIMKEDGSMARRGDKFLSDFALKHNLKTLYVSDLISYRLENESLLKMFCQEEREFLKHQTQCYTFLDHQQKNHYAFKFKGAKTHDLAPLVRFHPIKEDFDFLTTDAFEVFFKALEYLKHEGGYLIFMNTHSKENNVVKDFGIGALVLKNLGIKDFRLLSSCEDRQYKALSGFGLKLVETISL
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: TRO_ARATH
Sequence: MESLQSNSKIEEAEQNPKIEEAQVSVSLPEEPTGVLLPSELVDDSAPPESSDAVEESIETASEAEVSISLLEGTTTGTALLPSEENDLAPLESSGIIEEPIDTDLEKLDVVAMDVDQPGSDLKIESDSFSEEAPTTSSSDNPKSPKLDSVANQNGSAMEEDEGDEEQDDPPHKKLKQLDCLTSVAVKEEEEPEQVLPSEAMVVEEAATLVASAAKKSKSKKKNNNVWVTKSTRKGKKKSKANTPNPAAVEDKVLITPVPRFPDKGDDTPDLEICLSKVYKAEKVEISEDRLTAGSSKGYRMVRATRGVVEGAWYFEIKVLSLGETGHTRLGWSTDKGDLQAPVGYDGNSFGFRDIDGCKIHKALRETYAEEGYKEGDVIGFYINLPDGESFAPKPPHYVFYKGQRYICAPDAKEEPPKVVPGSEISFFKNGVCQGAAFTDIVGGRYYPAASMYTLPDQSNCLVKFNFGPSFEFFPEDFGGRATPRPMWEVPYHGFNGRLETNGSEDMKS
What is the function of this protein?
Trithorax-group gene homolog required for early embryogenesis (PubMed:20118203, PubMed:21423667).  Required for the expression of FLC and FLC homologs and represses flowering (PubMed:21423667).  Required for proper leaf growth and development (PubMed:21423667).  Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 'Lys-4' (PubMed:21423667).  Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed:21423667).  Involved in the transition from transcription initiation to transcription elongation (PubMed:23284292).
What are the official names of this protein?
Protein TRAUCO, Protein ASH2 RELATIVE, AtASH2, AtASH2R.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_CUPNH
Sequence: MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYTRAKLKDSMRLALRKRPVSAEAIDEAITRIEEKLLALGEKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVSEFRDVLDEFAASTPRKG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL17_NEIMA
Sequence: MRHRNGNRKLNRTSSHRAAMLRNMANSLLTHETIVTTLPKAKELRRVVEPLITLGKKPSLANRRLAFDRTRDRDVVVKLFGDLGPRFTARNGGYVRVLKYGFRKGDNAPLALVELVDKPAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: VKT3_VIPAA
Sequence: MSSGGLLLLLGLLTLWAELTPVSTRDRPKFCYLPADPGRCLAYMPSFYYDSASNKCKKFIYGGCRGNANNFKTWDECRHTCVASGIQPRIASN
What is the function of this protein?
Serine protease inhibitor that principally inhibits alpha-chymotrypsin (Ki=4. 3 nM).  Shows weak inhibition on trypsin (Ki=5100 nM), and plasma kallikrein.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 3, Venom basic protease inhibitor 3, Venom chymotrypsin inhibitor, cVamChi.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPS_YERE8
Sequence: MSTAKLVKAKSSELIYTRNDVDEHTKTLTIKLLNELVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTTINDHLDTFAERAVQLGGIALGTAQLVTEKTPLESYPTRIHSVQDHLKELADRYGVVANFVRKAITEVKDEDSADMFTAASRDLDKFLWFLEANLENQ
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECHA8_MYCTU
Sequence: MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRAPQFTHR
What is the function of this protein?
Could possibly oxidize fatty acids using specific components.
What are the official names of this protein?
Probable enoyl-CoA hydratase EchA8.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: EIF3B_BOTFB
Sequence: MAPSFDHLPDPEEDEYDEEELDISDLRERFEVQLEQGLDTFVVIDGLPEVNEDTKPKLIKFLLRKLDSVGQTKKDSIHMPIGPDGKSHKFAFVEYSSPVEAIAACKALDGVPLDKKHTLRVNKLTDIDRYGREGRIDENYTPPKIEEFTEKEHLRSWLADPAGRGRDQFVMYKDDRVQVLWNNEKDAPESIVDRQHWTESFVQWSPQGTFLTSMHQQGVQLWGGPSWTRQKRFAHPFVNLVDFSPGEKYLTTWSNRPITIGEEGHPALSIDDDGKNYVIWDIETGLPLRSFANLDLPSNSVDADGNPIKRKIQWPAFKWSSDDKYVARLTQGSSISVYELPKMNLLDKTSIKIDGVMDFDWAPATPHREGVKTYEQLFCYWTPEIGSNPAKVGLMSIPSKEVVRTLNLFSVTDAKLHWQSDASYLCVKVDRHSKSKKSLATSLEIFRVKEKGVPVEVVDSIKDTVINFAWEPKGDRFVIITTAEVVAATAVPPKTSVSFYCPEKVKGNGVGNFKHIRTYDKKNSNAIYWSPKGRFVIVATVHSQQSFDMEFYDMDFEGEKPESDKDLTANLQLMNTADHYGVTDIDWDPTGRFVATSASIWKHTMENGYHLYDFKGEQLREEPVEKFKQWLWRPRPPTLLSKEEQKQIRKNLREYSKVFDQEDADRGASADLAVVEHRRRLLDEWLAWRANMEEDVKADREDAGLPLDPLEPLKSKMASGDEGQAIEIEEIVEEIVEETEEIIS
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3, p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_ALIF1
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVEGLFMKNWEEDDNEEYCTAAEDLADAQAVCDKLGIHLHTINFAAEYWDNVFEYFLEEYKAGRTPNPDILCNKEIKFKAFLEFADEVLDADFIAMGHYVRRTFPTAEEIANGIKPQMLRGLDSNKDQSYFLYTLSSEQVARSLFPVGELEKPEVRRIAEEQGLITAKKKDSTGICFIGERKFTEFLGKYLPAQPGNIETPEGKVIGQHQGLMYHTLGQRKGLHIGGTKGGGGNEDPWFVGEKDLKRNVLIAVQGKDHPLLKSQGLLASQLHWVDRTPIKAPLSCTVKTRYRQTDIPCTIIPVDDENIKVIFDEPQIAVTPGQSAVFYLDEVCLGGGIIEERI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_BARBK
Sequence: MSMSDPLGDMLTRIRNAISRKKSKVVTPASKLRARVLDVLKLEGYICGYNQIDSGNGKFEFEIELKYFENSSVIRTISRISKPGRRVYVSTKSILQVANGLGISILSTPKGVMTDHEAREQNVGGELLCRVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PSBF_BOWSE
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MGMT_MOUSE
Sequence: MAETCKMKYSVLDSPLGKMELSGCERGLHGIRLLSGKTPNTDPTEAPATPEVLGGPEGVPEPLVQCTAWLEAYFREPAATEGLPLPALHHPVFQQDSFTRQVLWKLLKVVKFGETVSYQQLAALAGNPKAARAVGGAMRSNPVPILIPCHRVVRSDGAIGHYSGGGQAVKEWLLAHEGIPTGQPASKGLGLTGTWLKSSFESTSSEPSGRN
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FPR1_RABIT
Sequence: MDSNASLPLNVSGGTQATPAGLVVLDVFSYLILVVTFVLGVLGNGLVIWVTGFRMTHTVTTISYLNLALADFSFTSTLPFFIVTKALGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCICVLHPVWAQNHRNVSLAKKVIVGPWICALLLTLPVIIRVTTLSHPRAPGKMACTFDWSPWTEDPAEKLKVAISMFMVRGIIRFIIGFSTPMSIVAVCYGLIATKIHRQGLIKSSRPLRVLSFVVASFLLCWSPYQIAALIATVRIRELLLGMGKDLRIVLDVTSFVAFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALSEDSAQTSDTGTNSTSAPAEAELQAI
What is the function of this protein?
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors.  Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.  Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity).  Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis (By similarity).
What are the official names of this protein?
fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: FMT_RICAM
Sequence: YFSYNDKIIKILEAEYLNADHHFTAGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTVLK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y058_ATV
Sequence: MGLLESRVLALKTAVLNAIQDATRLFTGPSTGSRKIRKNLICCCRAGRLAGKVFLILH
What are the official names of this protein?
Uncharacterized protein ORF58.
Protein: TXIP1_MOUSE
Sequence: MANLQERKSFSKPRISIQASGGTPEAKGIEKRKLSQKRRTLPLQLSLGGHLSPWPTYTSGQTVLHNRKPCSDDSRNRANSCQQQSMSISKPKYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQKERIRSLEPLKAKIVTMNEDCSERVLAMRAEERYEISVLKKEKMNLLKLIDKKNEEKISLQSEVAKLRRSLAEEYLRYLTERDARKILIGDLNELRYQQEDMSLAQTPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANSGDVVPRRDLEMQEKTNMELQEQLESLKADYEEVQKEHELLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESIIAGGPERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDAIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERIAEEQKEPFPDFFFNFLERRFGVNDAMAWAYTIFENIKLFRSSEIMNQFYAVLMGKNLESVYINQKKTLSHLLKELLSVDTQNEGSITMEQFSTILKTTFPLKKEEQIQELMEAVGWGPDSSNTDMLNYRSLFNEDEEGQSEPFVQRLWEQYESDKEAYLEELKQELDLDPLEDVTLLKMRGTLMNIDPTMDKQTLSAYLSQAYQIPAIDVPLEDEEKQGIISIKVETALDRLRMADTKRVGPREPDPAS
What is the function of this protein?
Possible role in spermatogenesis.
What are the official names of this protein?
Translin-associated factor X-interacting protein 1, Trax-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: ATG1_DEBHA
Sequence: MSTTSIESNNDIGRSVKTIGVYSIGPEIGKGSFATVYKCFNTKTNESVAIKSVVRSKLKSKKLVENLEIEISILKTMKHPHIVGLLDYKQTTSHFHLVMDYCSMGDLSYFIRKRNQLIKTHPVISSLLERYPSPEGSHGLNEVLVIHFLKQLVSALEFLRNKSLVHRDIKPQNLLLCPPLHSKQEFKDGGFVGLWELPLLKIADFGFARFLPSTSMAETLCGSPLYMAPEILRYEKYNAKADLWSVGAVLYEMTVGKPPFRADNHVQLLKNIEKSNDRIKFPSAAQVPESLKRLIRSLLKYNPTERVSFNEFFNDPLIVNDLEGNDEPLETSEMDENLFISEYISPIKSSQKSQYIEPITTEVAVKEKSKQDLPAREVSTHASESQTKAVDTRPSSRDEEIKEIINKNSPGPETSRSIQPHNLKEKSLVLKNKDNDIILERDYVVVEKRAVEVNAIADELAHAGSGAVAINPRRTSSGSDNSYNGPNNMQLYRRPSLRSNSSGSQRRPSFTDRRISISISPTNALTKAIGLASNRLFGVNASGSPTNRLIEETDERLAINENNSSMNATNNTFSTILSNPNFANNLLIQKLNLPTSATVANNSQTNTSPQLSPQSKTDESVLNRLESLATKAHAINLFADVKFSQLIPSPPSSDALDDDLLHQNDMLPPKIVKSISEEGVVLYVKTLSLLAKGMVIASDWWYSQFEIDDPSNKNSNENPLKQSSNNNSDDLSLAVRINELVQWIREKFNECLEKAEFIRLTLQEANTLLSNEDSSEYMGNSNSVADKTRVVAEKLIFDRALEMSRNAAVNELVKEDLKGCELAYSTAIWMLEALLDEDSSNDEDRLDDEDKAMVEKFIVSIGNRLSVLKRKLEVV
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: ERPA_BURM7
Sequence: MNAVTESAATTEMPAPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVLNKNGVVLLVDAMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RS8_CITK8
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: APAG_SALG2
Sequence: MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQLLGRYWLITNGHGRETEVQGEGVVGVQPRIAPGEEYQYTSGAVIETPLGTMQGHYEMIDENGDAFTIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: GCST_SYNS3
Sequence: MDQNCTPLHDLCIAAGGRMVSFAGWEMPVQFSGLMAEHKAVRSDSGMFDISHMGVLRIEGANPKDALQQLVPSDLHRIGPGQACYSVLLNEQGGIIDDLIIYDLGPSLLDESHETLLVVINAACAETDTAWIRQHLERADLQVLDEKKDGVLLALQGPKAIGLLERLSGSDLSELPRFGHCSLNIHGLQAPVFTARTGYTGEDGVELLLKADDGRQLWQLLLEEGVTPCGLGARDTLRLEAAMHLYGQDMDAATTPFEAGLGWLVHLEMPALFIGRQALEQAAEQGPSKRLVGLKLQGRSIARHDYPVIHNGATVGVVTSGSWSPTLQEPIALASLPPALAKLGTELSVEIRGQLQPATVVKRPFYRRS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.