PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_METMJ
Sequence: MNLAFRFSYFGDRFFGSQMQPDLCTVEGEFIGACRLLRLFDDWREANFATAGRTDRGVHARSQVCSFLTDKPERAIEALNRVLPADIWCTGWAEAPDGFHPRYSAVSRTYRYYFSAPGDAAAMHEAAQEFLGRHDFSAFARAGDRNPERRILASRVFIDGEFAVFEVTGESFLWNMVRCMATMLGRVGRGEAEAGEIARLLTGPVERRVAAAPPEGLILWDIDYGIPFTPLPIDAGSSRHLGDRHRYHVLMAKISAHLAQDHRQPDTPGI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PAND_ACIC1
Sequence: MLRTMLHAKIHRATVTRADLHYVGSITLDLDLMEAADILPGELVAVADINNGNRLETYVIAGERGSGVVGINGAAARLVHPGDLVIIMSYVQLPDAEARRHHPRVVFVDAENRIIGTGTDPAEPLPGSGLLSGHHT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL402_YEAST
Sequence: MHSLKGDFVSNNVTISHCHLPLSPATAIAIIICFRIVTDLKLSRLTYAFYLPGPISFLPVIPI
What are the official names of this protein?
Putative uncharacterized protein YLR402W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RFNG_DANRE
Sequence: MHLSHVASNKTCFLLSLAFCALLVLLIPSLQPPQRQADLPQPRPHAKPAKHPLKNSLYRPNEDTRGGGFTQTPPPDNLEKMDDLNSHYRDFLDLRDIFIAVKTTRKYHKSRLQLLSQTWVSRAKEQTFIFTDGEDKELRLKAGLNIINTNCSAAHTRQALCCKMSVEYDKFIESQKKWFCHVDDDNYVILPSLLELLSSYSHTQDVYLGRPSLDHPIEAAERVKSDGSVSVKFWFATGGAGFCISRGLALKMSPWASLGNFITTAEKIRLPDDCTIGYIIEALLEVPLTHTGLFHSHLENLQRLPAENILRQVTLSYGGFENRRNVVSVGGAFSLAEDPTRFKTVHCKLYPDTEWCPRKTRH
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (By similarity).  Regulates neurogenesis in the hindbrain; involved in boundary cell specification via Notch-mediated activation of wnt1 expression (PubMed:15068793, PubMed:15659486).
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase radical fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RS15_CYTH3
Sequence: MYLTSEIKKEIFKTNGTAKSATDTGSPESQIALFSHRIAHLTEHLKVNKKDYSTQLGLMKLVGKRRRLLNYLQKTEISRYRAIIAQLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TXE1A_ETHRU
Sequence: MRPSFPLLLIMLLVCTAHHMVSGENAQSCTPEQQKTCKQYSCINPCCENNQCRCGCGILEGESK
What are the official names of this protein?
U-scoloptoxin(14)-Er1a, U-SLPTX(14)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_BACAH
Sequence: MARYTGPAWKLSRRLGISLSGTGKELEKRPYAPGPHGPNQRKKLSEYGLQLQEKQKLRHMYGMTERQFRRTFDQAGKMPGKHGENFMILLEARLDNLVYRMGLARTRRAARQLVNHGHIMVDGARVDIPSYRVKPGQTISVREKSNNLVVVKEAIEVNNFVPEYLTFDADKLEATYTRHAERAELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NU5C_ATRBE
Sequence: MEQTYEYAWIIPFIPLPVPMLIGAGLILFPTATKSFRRMWAFQSVLLLSIVMIFSIYLSIQQINSSSFYQYVWSWIINNDFSLDFGYLIDPLTSIMSILITTVGIMVLIYSDNYMAHDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGLCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFEIFNNLSSNNEVNFLFVTLCAVLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFRVIPYIMYLISVIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMETIVGYSPAKSQNMGLMGGLRKHVPITQITFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWATAGLTAFYMFRIYLLTFEGHLNVHFQNYGGKQKTPFYSISLWGKKGVKKNSYLLTMNNNESTYFFSKTKYPIDKNGRKMTRPFMTIAHFEHKTVYSYPYESDNTMLFPIFVLGLFTLFVGSIGIPFNQEGVNLDILSKWLAPSINLLHQKSNNSMDWNEFLKDAVLSVSIAYFGIFLASFLYKPIYSSLKNFELINSFVKKGPKRILWDKIINGIYDWSYNRAYIDAFYTRFFVGGIRGLAEFIHFFDRRVIDGMTNGVGVISFIVGEGIKYIGGGRISSYLFLYLAYVSVFLLVYYLFFLTF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1500_CLOTE
Sequence: MILSNLSYIDNKELETINIVEGVCVFSKNVGKDIMASFKNVVGGEIKSYSEMVRDVKDTAVKKMVEEAKNLGADAVINIRYAMTSMSQGSTLAVIVSGTAVKVKGE
What are the official names of this protein?
UPF0145 protein CTC_01500.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: MIC19_BOVIN
Sequence: MGGTASTRRVTFEADENENITVVKGIRLSENVIDRMKETSPSGPKSQRYSGTYGASVSDEELKRRVAEELALEQAKKESENQKRLKQSKELDAEKAFANEQLTRAILRERISNEEERAKAKHLAKQLEEKDRVIKKQDAFYKEQLARLEERSSEFYKVTTEQYQKAAEEVEAKFKRYEYHPVCADLQAQILQCYRQNTQQTLSCSALASQYMRCVNQAKQSTLEKGG
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.  Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
What are the official names of this protein?
MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Lipid-anchor; Intermembrane side. Cytoplasm. Nucleus. Mitochondrion.
Protein: SEPF_STRT2
Sequence: MAIKDAIEKIVSYFDADEVTDHEDVAKERPVKVQKTEQTPSQQQRKPERPQETVPPRRQHIKSDVQETQVLRSLSLSRSQVNQGSQQMNTTKTTIAIKYPKKYEDAQEIVELLIENECVLIDFQYMLEAQARRCLDFIDGASKVLTGNLQKVGSSMYLLTPINVVVDIEEIGLSHGNQESTFDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RL19_PAEAT
Sequence: MHILDSVDAASLRNDVPEFRAGDTLKVHVNIIEGKNSRVQVFQGFVLGRQGDGVRETFTVRKVSFGVGVERTFPVHSPIIDKIEVVTKGDVRRAKLYYMRALRGKAAKIKEKRDFAK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: EKIA_DICDI
Sequence: MMAKTKGSYEVFHYTVTKDKVNKGLCDIARYFVPEYRNSKDEDLTIQKLNGGITNVLYLVEDKNIEQKYRYLPVVIRLYGYKSEEIIDRKNELIIQTEADQNGLGAKFYGLFDNGCIYGFIKGEPLAYEDISKPTMQTCIAKEIAQWHSIEMPTRKNPSLWPTIKKWAALAPDVYPVPEKNEYYQSINVKKMIEEGKMLEQRLAQLNSPIVFCHNDLLSGNIIYDPSQNCASFIDFEYANYNFRGLELGNHFNEYAGFGPDYSLYPNKESQIHFLTDYHRSLFKTEPTQDELEKLYIESNQFSLASHLYWGFWAIVQAMNSQIDFDYLEYGKARFDRYYETRDQFLNLN
What is the function of this protein?
Highly specific for ethanolamine phosphorylation.  May be a rate-controlling step in phosphatidylethanolamine biosynthesis (By similarity).
What are the official names of this protein?
Probable ethanolamine kinase A.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPA2_MOUSE
Sequence: MKPSSEEEGELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK
What is the function of this protein?
Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.  Has been implicated as the pharmacological target for lithium Li(+) action in brain (By similarity).
What are the official names of this protein?
Inositol monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX1_MAGSA
Sequence: MTFRQYIELLKPRIALMIALTAITGYGAVATKVDPVALLLLTLAMILGSAASAVFNHVWDRDIDRLMRRTSRRPMATGAGTPALGFALAVVLMVAGMALANAAFNWVVALHLFLGGFVYVAIYTVWLKRRHWTNIIIGGAAGSFAVLAGAAAVDQTQWLLPMVLALVLFLWTPSHFWSLAILLADDYRQAGVPMLPVVVGAKRTAWCILANTVILVGASLLPWGLGLLGNVYGFVAAVSGAVLLGFNVVLVRDTSRRWAGWNFAASMPYLLLLFIAVFADKHW
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSI_SALG2
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPLMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: PITM1_HUMAN
Sequence: MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGSGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYHSVKTGRGPLSDDWARTAAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWTELSMADIRALEEETARMLAQRMAKCNTGSEGSEAQPPGKPSTEARSAASNTGTPDGPEAPPGPDASPDASFGKQWSSSSRSSYSSQHGGAVSPQSLSEWRMQNIARDSENSSEEEFFDAHEGFSDSEEVFPKEMTKWNSNDFIDAFASPVEAEGTPEPGAEAAKGIEDGAQAPRDSEGLDGAGELGAEACAVHALFLILHSGNILDSGPGDANSKQADVQTLSSAFEAVTRIHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYSAFLRSPEGAGFCGQVALIGDGVGGILGFDALCHSANAGTGSRGSSRRGSMNNELLSPEFGPVRDPLADGVEGLGRGSPEPSALPPQRIPSDMASPEPEGSQNSLQAAPATTSSWEPRRASTAFCPPAASSEAPDGPSSTARLDFKVSGFFLFGSPLGLVLALRKTVMPALEAAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLTVPRYQKFPLGDGSSLLLADTLQTHSSLFLEELEMLVPSTPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKILERWWGTKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKERPQLAECEEPSIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLSGRFMYGPLDVVTLTGEKVDVYIMTQPLSGKWIHFGTEVTNSSGRLTFPVPPERALGIGVYPVRMVVRGDHTYAECCLTVVARGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHASSGPPRAALGKSSYGVAAPVDFLRKQSQLLRSRGPSQAEREGPGTPPTTLARGKARSISLKLDSEE
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) between membranes (PubMed:22822086, PubMed:10531358).  Binds PI, phosphatidylcholine (PC) and phosphatidic acid (PA) with the binding affinity order of PI > PA > PC (PubMed:22822086).  Regulates RHOA activity, and plays a role in cytoskeleton remodeling (PubMed:11909959).  Necessary for normal completion of cytokinesis (PubMed:15125835).  Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus (PubMed:15723057).  Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus (PubMed:15545272).  Required for protein export from the endoplasmic reticulum and the Golgi (PubMed:15723057).  Binds calcium ions (PubMed:10022914).
What are the official names of this protein?
Membrane-associated phosphatidylinositol transfer protein 1, Drosophila retinal degeneration B homolog, Phosphatidylinositol transfer protein, membrane-associated 1, PITPnm 1, Pyk2 N-terminal domain-interacting receptor 2, NIR-2.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets (PubMed:12225667). Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis (PubMed:15125835).
Protein: SECE_BUCAI
Sequence: MNKHHYNRNKHKIPEKVKWISISIFFILSFFINMCFYETQLFIRIFIISCLMLCAIGTMIYTKKGKDILLYIVMSKKEMQKIIWPKYKETLYTTFIVISVTIFISFILWSIDSVIFRLIAFIISLRF
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOA_ACIBT
Sequence: MTRTANEFLTPQAIKVEAVSGTSAKVILEPLERGFGHTLGNALRRILLSSLPGAAVVEVEIEGVEHEYSTLEGLQQDIVELLLNLKGLSIKLFDQNEAYLTLEKQGPGDITAADLRLPHNVEVVNPEHLIGTLSATGSLKMRLKVSQGRGYETSDSRFPEGETRPVGRLQLDASYSPIKRVSYTVENARVEQRTDLDKLVIDLETNGTVDPEEAIRKAATILQQQIAIFVDLQKDQTPVAQEPREEVDPILLRPVDDLELTVRSANCLKAENIYYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASKGLQLGMRLENWPPASLRMDDRFAYRSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LEU1_MYCTU
Sequence: MTTSESPDAYTESFGAHTIVKPAGPPRVGQPSWNPQRASSMPVNRYRPFAEEVEPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARKRRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLTQCRPELIERTFQACSGAPRAIVHFYNSTSILQRRVVFRANRAEVQAIATDGARKCVEQAAKYPGTQWRFEYSPESYTGTELEYAKQVCDAVGEVIAPTPERPIIFNLPATVEMTTPNVYADSIEWMSRNLANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSRGVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDADAADCDVDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQIEFSQVIQKIAEGTAGEGGEVSPKEMWDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSITATVKINGVETEISGSGNGPLAAFVHALADVGFDVAVLDYYEHAMSAGDDAQAAAYVEASVTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTSKTVWGVGIAPSITTASLRAVVSAVNRAAR
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (alpha-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (PubMed:11914056, PubMed:16846242).  Active on small alpha-keto acids such as 3-methyl-2-oxobutanoate, pyruvate, alpha-ketovalerate, and alpha-ketobutyrate; only uses acetyl-CoA (PubMed:16846242).  Complements an E. coli deletion (PubMed:22352945).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: RK2_PLAOC
Sequence: MAIHLYKTSTPSTRNGAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNKKNIEGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDSIVSGTEVSIKMGNALRLGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATFGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKNPTTPWGYPALGRRSRKRNKYSDSLILRRRTK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_METSB
Sequence: MALKTFNPVTPSLRQLVIVDRSDLYKGKPLKQLTEGKSSSGGRNNNGRITVRFRGGGHKQTYRIIDFKRRKLDVAAKVERIEYDPNRTSFIALIRYADGEQSYIIAPQRLSVGDEVVSSQQADVKPGNAMPLASMPVGTIVHNIEMKIGKGGAMVRSAGTFAQVVGRDQGYVIIRLNSGEQRLIHGQCFATVGAVSNPDHMNASIGKAGRSRWLGRRPHNRGVTMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKSTTKFIVTSRHKSKKKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DCOR_BOVIN
Sequence: MNSFSNEEFDCHFLDEGFTAKDILDQKINEVSYSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRTIVKTLAAIGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELDIDVIGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFNMYLLDIGGGFPGSEDVKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKLVLKEQTGSDDEEESTDRTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPTWQLMQQIRTQDFPPGVEEPDVGPLPVSCAWESGMKRHSAACASTRINV
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: GOG8B_HUMAN
Sequence: MAEETGQSKLAAAKKKFKEYWQRNRPGVPAAAKRNTKANGSSPETAASGGCHSSEASSSASSSLHARQSPCQEQAAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKKLNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMDLLEEKADLREHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGDGVAACGSYSEGHGKFLAAARNPAAEPSPGAPAPQELGAADKHGDLCEASLTNSVEPAQGEAREGSSQDNPTAQPVLQLLGEMQDHQEHPGLGSNCCVPCFCWAWLPRRRR
What is the function of this protein?
May be involved in maintaining Golgi structure.
What are the official names of this protein?
Golgin subfamily A member 8B, Golgin-67.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
Protein: CYSX_ECOLI
Sequence: MRRHRLQHHGTCANLRAAPNFNIAEDFRARANHHTFTNFRVTVTTRFTRTAKRHRLQNRYVVFNHRRFTNDDACRVVKHDTATNFCCRVNIDLERHRNLVLQKDCQCATPLIPQPVTDAIGLQGMKTLQV
What are the official names of this protein?
Putative uncharacterized protein CysX.
Protein: RECF_RICB8
Sequence: MKNIFLHSLIVENYRNFKNLELKTDNIPITIIGENGSGKTNILEAISLFYPGRGLRSARLADICRESEDHCSVRALLQSKLGLAEFSTQIKRISNRRTTEYNNSKIANNELSKFTSMVWLTPQMEGIFMSGTSDRRKFFDRIVYNFDPKHAELVSKYEHYMQERNKILAEDMWDNNWLKTIEEKMADTSIYIANNRLKTLEFMQQAIDDLENEFPKAELSIDGMVEQKILNGEEDVVGFIAAELHKTRDKDKLLGRTSFGVHKSDFLVKHKHKNILAKFCSTGEQKAILIAIILAEMNYAIKLTKTAPILLLDEVFVHLDDRRRNYLTEFFISINLQLWVTATDLKGIEEFGNKSQLIKL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH10_ORYSJ
Sequence: MAMKRVVFLLLLVAASALVKSSRGGGGGEEKLGKFYGWRRHLSSGPAASSLVLSGDLVDKIWSVCLQDIVSPEDTFGFGESFAWDELSSHSTEDELKATLFMELMALLPPEKSSFTYDCIRANCFSLGVPQIFSVALSNYLESQKSLVGSNFYPRRRLVDKLIGDAPSMAPAFAPSMSSGGEVHSPLSVAEAPLTPSNSLNMEPPSPYYPSKSAHKHQGVAPPVSPSEEYHDYMKVVLIAVLPTAALSFLAAFLCFYCCGCNKSKVSVGEQRDDHPLLHLQFSNLPGSSPDVHVPASPLHKDDHGVRPSNAGVSMSKCFPCCFKTSSDATTPTLVTGGTQENNATSDAPKLMPPPPPPPPPPPPPPPPPPPRPPPPPPPIKKGAPPPAPPKATMARFPKLSPTESSRSEESSASELASESSETEVNAPRAKLRPFYWDKVLANPDQSMAWHDIKFGSFHVNEEMIEELFGYGAGNQNNVKDKEISIADPSPQHVSLLDVKKSCNLAVVFKAMNVRAEEIHDALVEGNELPRLLLETILRMKPTDEEEQKLRLYNGDCSQLGLAEQVMKALIDIPFAFERIRALLFMSSLQEDASSLRESFLQLEAACGELKHRLFLKLLEAILKTGNRLNDGTFRGGANAFKLDTLLKLSDVKGADGKTTLLHFVVQEIIRSEGVREARLAMENGRSPPFPSTSDDNSNESLQEDGNYYSNLGLKIVSGLSNELDNVKRVAALDADALSTSVANLRHELLRAKEFLNSDMASLEENSGFHRSLESFIEHAETETNFLLKEDKRLRMLVKRTIRYFHGNDEKDDGFRLFVIVRDFLVMLDKACKEVGASQKKATNKSQANGNSNNPSSQSNPQEQQFPAVLDHHFDSSDSND
What are the official names of this protein?
Formin-like protein 10, OsFH10.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.