PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_SHESR
Sequence: MVKKNSKKAAPATIARNKRATFEYRFEEKMEAGLSLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPIRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ARCH_METMA
Sequence: MPSQGKKYEYLEHTADIKFLAYGETVEEVFENAALAMFNVIIDTEKVSGETEREVLLTSPDLESLLVDWLSELLYLFEVDEVVFWKFQVEEIREEEGEYSIKALASGEKYYPESHPFETEIKAVTYNQLELEKTAGGWKAQVVVDI
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: RAS1_CANAL
Sequence: MLREYKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRVKDSDNVPVLVVGNKCDLEMERQVSYEDGLALANSFNCPFLETSAKQRINVEEAFYGLVRNINQYNAKIAEAEKQQQQQQQQQNANQQGQDQYGQQKDNQQSQFNNQINNNNNTSAVNGGVSSDGIIDQNGNGGVSSGQANLPNQSQSQSQRQQQQQQQEPQQQSENQFSGQKQSSSKSKNGCCVIV
What is the function of this protein?
Required for the regulation of both a MAP kinase signaling pathway and a cAMP signaling pathway.  The activation of these pathways contributes to the pathogenicity of the cells through the induction of the morphological transition from the yeast to the polarized filamentous form (By similarity).
What are the official names of this protein?
Ras-like protein 1, Ras homolog type B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RCLC_ECOLI
Sequence: MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSITPFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIALLVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLVLKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY
What is the function of this protein?
Probably involved in reactive chlorine species (RCS) stress resistance.
What are the official names of this protein?
Inner membrane protein RclC, Reactive chlorine resistance protein C.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAX_DINSH
Sequence: MLLAIDCGNTNTVFAIHDGTDFVAVWRTATEHQRTADQYYVWLQSLMQMQKIEVEITEVIISSTVPRVVFNLRVLCDRYFNCRPLVVGKPGCALPVDVRVDAGTQVGPDRLVNTVAGFTQFGGDLIVVDFGTATTFDVVDVDGAYVGGVIAPGVNLSLEALHNAAAALPHVDISMPDTVVGTNTVACMQSGVFWGYVGLVREICAQIKAERARPMRVIATGGLAPLFSQGAELFDAWVDDLTMQGLVTINSYNREA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1349_SULTO
Sequence: MSSGIVGWGAYVPRYRLNVLEIAKLWGYDEGVVKSLGLMEKAVPSHDEDSTTMAWEAARNALMRAKIDPSEIKAVLFGSESKVYAVKPTSTIIIDSLGISHETLSADLEFACRAASVGLRLLSGMVEANRIKYGLVIGSDVAQSNPGDVLELSSAAASVAYIVGPADESSAIIEYATSYTTDMPDFWRRDGMPYPLHGEAFTGEPAYFAHIISAVQLLLKEGGYSISDFDYFVFHQPNGKFPLQVAKKLGVPLEKVKEGLVSPYIGNPYNASALLGLAKVLDIAKPGQRILVAPFGSGAGSDAFSILVTDKIEERQKLAPRVEDYINNKKVISYSVYAKTTNKYKVYE
What are the official names of this protein?
UPF0219 protein STK_13490.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: YEJL_ECOUT
Sequence: MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: PYRB_BAUCH
Sequence: MINPLYRKHIISINDMSSNELELVLNIAAHLKFKPQPELLKNKVIASCFFEASTRTRLSFETAIHRLGASVVGFSDAHSTSLSKKGETLADTISVISTYVDAIIIRHPHEGAARLATEFSGTVPILNAGDGANQHPTQTLLDLFNIYETQGKLNNLRIAMVGDLKYGRTVHSLTQALIKFDSNHFYFIAPDTLGMPSYILHTLIDHDIKYSMHLNLAEVIPELDILYMTRVQKERLDPTEYINVKAQFVLQIHHLLHARANMRILHPLPRVDEIAYEVDQTPYAYYFQQAGNGVFTRQALLALVLNKYLTE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PROA_THEP1
Sequence: MDELLEKAKKVREAWDVLRNATTREKNKAIKKIAEKLDEKRKEILEANKIDVEKARERGVKESLVDRLALNDKRIDEMIKACETVIGLKDPVGEVIDSWVREDGLRIARVRVPIGPIGIIYESRPNVTVETTILALKSGNTILLRGGSDALNSNKAIVLAIKEALRETEVPESSVEFIENTDRSLVLEMIRLREYLSLVIPRGGYGLISFVRDNATVPVLETGVGNCHIFVDESADLKKAVPVIINAKTQRPGTCNAAEKLLVHEKIAKEFLPVIVEELRKHGVEVRGCEKTREIVPDVVPATEEDWPTEYLDLIIAIKVVRDVDEAIEHIKKYSTGHSESILTENYSNAKKFVSEIDAAAVYVNASTRFTDGGQFGFGAEIGISTQRFHARGPVGLRELTTYKFVVLGNYHVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y169_PASMU
Sequence: MEIIIISGHSGAGKSVALRCLEDIGYYCVDNLPLDLLPQLASILSTNQQSVAISLDIRNLPHSSKTLENLLTEVQQQHQIKLIFLDADRGTLIRRYSDSRRLHPLSTQDLSLEAAIDAERKYLDPLTQHADLIIDTTRLSTHELAERLRDFLCEKSDKALKIIFQSFGFKYGLPLDADYVFDVRFLPNPHWIPELRPLTGLDAPVAEFLNKQNEVNHFIYLTRNYIETWLPMLEQNNRSYLTIAIGCTGGKHRSVYITEQLGEYFQAKGKNVQIQHKSLAKHKKANTQ
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein PM0169.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: UPPS_ECOLI
Sequence: MMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA
What is the function of this protein?
Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: YACG_NEIM0
Sequence: MAESRQTRLQVKCPTCQTAVVWKPENAFRPFCSQRCKLIDLGGWADEEYTVTAQEEGLLEISEPDGAYR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RHLB_SHESR
Sequence: MSQTHLSNQKFADLPLHPEVKQALAENGFEFCTPIQALSLPVLLQSKDIAGQAQTGTGKTMAFLVATFNHLLSTPIPENRQLNQPRAIIMAPTRELAIQIAKDAILLAKHTHLKVGIVYGGESYDVQRKVLDQGVDILIGTTGRIIDYVRQGIISLNAIQAVVLDEADRMFDLGFIKDIRFLFRRMPNADQRLNMLFSATLSMKVQELAYDHMNDPVKVEIAPEEKTSKNIKEEIFYPSQEDKIRLLLTLIEEDWPEKAIVFSNTKHSCENLWSWLEGDGHRVGLLTGDVPQKKRIRILEQFTQGQLDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGNKGVSVSFACEEYALNLPAIESYINHSIPVSNYDRDALLDDIPPPVKIHRKHPAGARNLRERSGAGRPQGAHRSGGRPPRHDRTRRQP
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLCZ1_RAT
Sequence: MESHYELAEARWFMSKIQDYFRGGKISAGITHKLLEKLDFPCHFAHVKRIFKENDRHNQGRITTEDFRTIYRCIVHREEIVEIFNTYTENRKILPEDSLIEFLTQEQYEMEMDESSSVEIIQKYEPIAEVKNERQMSIEGFARYMFSSECLLFKETCNTVYQDMNKPLNDYYISSSHNTYLISDQILGPSDIWGYISALVKGCRCLEIDCWDGAQNEPIVYHGYTLTSKLLFKTVIQAINKYAFVTSDYPVVLSLENHCSPGQQEVMTDILQSTFGDFLLSDILDEFPDSLPSPEALKFKILVKNKKVGTLSETRERLGTDKRGIALDLEEEIYENEDEDSGKEPETWDDFLSRVKEEQEADPSTLSGIADAKKKIRKLRVALALSDLVIYTKAEKFRNFQYSRVYQQFNETTSMGESRARKLSKLRAHEFIFHTAAFITRVYPKFTRADSSNFNPQEFWNVGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYVLKPDFLRDTTLGFNPNEPEGDGHPVTLTIRLISGIQLPVNVPSNTSDIIVIIEVYGVPNDHMKQQSRAVKNNAFSPRWNETFTFLIQVPELALIRFVVETQGFLSGNELLGQYTLPVLCMNKGYRRVPLFSKSGANLEPSSLFIYVWYYRE
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner.  Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage.  Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.  May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, PLC-zeta-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Exhibits alternative cytoplasmic/nuclear localization during development. Translocates from the pronucleus into cytoplasm upon nuclear envelope breakdown for mitosis and localizes again to the pronucleus at interphase following meiosis and mitosis (By similarity).
Protein: ULA1_MOUSE
Sequence: MAQPGKILKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNLVSGEDAGNNFFLQKSSIGKNRAQAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTIVVATQLLESTLLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHLQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYNETNGRIPKSYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPTFWILARALKEFVAKEGQGNLPVRGTIPDMIADSNKYIKLQNVYREKAKKDAAAVGNHVAKLLQSVGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTVNKDEIISSMDNPDNEIVLYLMLRAVDRFHKQHGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
What is the function of this protein?
Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme.  E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.  Necessary for cell cycle progression through the S-M checkpoint.  Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation (By similarity).
What are the official names of this protein?
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane. Note=Colocalizes with APP in lipid rafts.
Protein: FETP_SHEB8
Sequence: MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNISKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKEVEIEGFVPEKDQD
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: UPPP2_MAGSA
Sequence: MLEALLLGVVEGLTEFLPISSTAHLMLIGDMLGFEGPPGKTYEIVVQLGAILAVCVVFRQRLWGVATTITQPRSFAFARNVMVAFLPAAVIGATLYKYIKQMLESPLVAAIALVVGGVAILVIERLVKRARIHDIEDMSPALALGVGFCQVLAMVPGVSRAGATIMGSMLLGLDRRAAAEFSFFLAIPTMCGASAYSLYKNWATLSFDGAGLIALGFVAAFLSALVVVKGFIGFVGRHGFAPFAWYRIAFGSLMAVLILMR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HLDE_SALAR
Sequence: MKVNLPAFERAGVMIVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEFNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPEPLHERINQALGSIGALVLSDYAKGALTSVQTMIALARQADVAVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIANYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPVELENAVRGRAATGFGVMTEEELKQAVASARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANGGEVMVLNFEDGCSTTNIIKKIQTESEK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: SYR_SHEON
Sequence: MKSHIQSLLEQTIESFKQQGILPADFEARIQVDRTKDKSHGDLATNVAMMLTKAAGKNPRELAQLIIDNLPASAYVAKVEIAGPGFINFFIDDSALANQLQAAIGDEHLGIKLPAPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRTLEFLGHKVIRQNHVGDWGTQFGMLLAYMEELRAANGEQAQLELSDLETFYRAAKLRFDESAEFATRARQLVVALQSGDEYCNKLWREFNDISLSHCHEVYERLGVSLTRADVHGESAYNADLEQVVNDLAAKGLLTESNGAKVVFQEEFRTKEGEPLPVIIQKADGGYLYATTDLAAMRYRSNVLKADRVLYFVDLRQALHFQQVFSLAKLAKFVREDMSLEHLGFGTMNGEDGRPFKTRTGGVVKLVDLLDEANTRALELVRSKNPDMDEATLAEIARVVGISAVKYADLSKNRTSDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRATDVDLSQAKIVLEHEKEKDLGNKLAQFGEILSRVVDKGQPHVLCGYLYELAGAFSSFYEACPVLAADNDEQKHSRLLLSQLTASTLQKGLNLLGIETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BRUME
Sequence: MTTRIDTKFAELKAEGRPALVTYFMGGDPDLETALKVMKALPKAGADVIELGMPFSDPMADGPAIQAAGLRALNAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNLIYIYGVERFLTDAKASGVDGLIVVDLPSEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAKVGEAVRHIKKSTDLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKAKGDPVAAATRLVHALAESVRATRLEAAQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RS27A_DROME
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKNYSTPKKIKHKRKKVKLAVLKYYKVDENGKIHRLRRECPGENCGAGVFMAAHEDRHYCGKCNLTFVFSKPEEK
What is the function of this protein?
Component of the 40S subunit of the ribosome.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: ATPB_CAMJJ
Sequence: MQGFISQVLGPVVDVDFNDYLPQINEAIVVNFESEGKKHKLVLEVAAHLGDNRVRTIAMDMTDGLVRGLKAEALGAPISVPVGEKVLGRIFNVTGDLIDEGEEISFDKKWAIHRDPPAFEDQSTKSEIFETGIKVVDLLAPYAKGGKVGLFGGAGVGKTVIIMELIHNVAFKHSGYSVFAGVGERTREGNDLYNEMKESNVLDKVALCYGQMNEPPGARNRIALTGLTMAEYFRDEMGLDVLMFIDNIFRFSQSGSEMSALLGRIPSAVGYQPTLASEMGKFQERITSTKKGSITSVQAVYVPADDLTDPAPATVFAHLDATTVLNRAIAEKGIYPAVDPLDSTSRMLDPNIIGEEHYKVARGVQSVLQKYKDLQDIIAILGMDELSEEDKLVVERARKIEKFLSQPFFVAEVFTGSPGKYISLEDTIAGFKGILEGKYDHLPENAFYMVGNIDEAIAKADKLKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GRPE_BACLD
Sequence: MAEEKQNEELNEQEELNETEAETAEAEQTAAEADAPAEETQTEMLEKQLKELQERLEEKENKLLRVQADFENYKRRARLDLEAAEKYRSQRIISDLLPALDNFERALQIDPDNEQTKSLLQGMEMVHRQILEALKNEGVEQIPSVGEQFDPNMHQAVMQVEDEAYESNAVVEELQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP7X_PIG
Sequence: RRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQNFHYLLQNNQPGVLIQVYEGERAMTRDNNLLGRFELSRIPPTPRGVPQIEVTFDIDANGILSVTATDRSTGRANKMTLTSDKGRLSKEEVERMVREAASHKVEDEAQRDRVAAKNSLEAYVFHVKGSLHEESLRDKIPEEDRCKVQDKCQEVPYLWLEHNQLAEKEEYEHQKRELEQIASISQLLGPCTWGSSCGAQAPKGGPSTGPVIEEVD
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GLGB_MYCTU
Sequence: MSRSEKLTGEHLAPEPAEMARLVAGTHHNPHGILGAHEYDDHTVIRAFRPHAVEVVALVGKDRFSLQHLDSGLFAVALPFVDLIDYRLQVTYEGCEPHTVADAYRFLPTLGEVDLHLFAEGRHERLWEVLGAHPRSFTTADGVVSGVSFAVWAPNAKGVSLIGEFNGWNGHEAPMRVLGPSGVWELFWPDFPCDGLYKFRVHGADGVVTDRADPFAFGTEVPPQTASRVTSSDYTWGDDDWMAGRALRNPVNEAMSTYEVHLGSWRPGLSYRQLARELTDYIVDQGFTHVELLPVAEHPFAGSWGYQVTSYYAPTSRFGTPDDFRALVDALHQAGIGVIVDWVPAHFPKDAWALGRFDGTPLYEHSDPKRGEQLDWGTYVFDFGRPEVRNFLVANALYWLQEFHIDGLRVDAVASMLYLDYSRPEGGWTPNVHGGRENLEAVQFLQEMNATAHKVAPGIVTIAEESTPWSGVTRPTNIGGLGFSMKWNMGWMHDTLDYVSRDPVYRSYHHHEMTFSMLYAFSENYVLPLSHDEVVHGKGTLWGRMPGNNHVKAAGLRSLLAYQWAHPGKQLLFMGQEFGQRAEWSEQRGLDWFQLDENGFSNGIQRLVRDINDIYRCHPALWSLDTTPEGYSWIDANDSANNVLSFMRYGSDGSVLACVFNFAGAEHRDYRLGLPRAGRWREVLNTDATIYHGSGIGNLGGVDATDDPWHGRPASAVLVLPPTSALWLTPA
What is the function of this protein?
Essential enzyme that catalyzes the formation of the alpha-1,6-glucosidic linkages in glucan chains by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.  Is involved in the biosynthesis of both glycogen and capsular alpha-D-glucan.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen-branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: UXAB_YERPE
Sequence: MQTLNRRDFPGRSHPDKIIQFGEGNFLRAFVDWQIDLLNEHTDLNAGIVVIRPIDTDFPPSLSTQDGLYTAVIRGLNEQGEAVRESRLIRSVNREINIYRQFDDYLALARDANIRFMFSNTTEAGIAWNEADQFSDAPPSSFPAKLTRLLFERFEHFDGAADKGWVLLPCELIDYNGEALRELVLRYASHWQLPAAFTHWLTENNTFCSTLVDRIVTGYPRDEVAALQTELGYQDSFLDTAEYFYLFVIQGPQGLAQELRLDQLDLNVRIVDDIKPYKERKVAILNGAHTALVPVAYLSGLDTVGQTMDDAQISRFVEKTITEEIVPVLDLPEDELLSFSQAVLSRFRNPFIQHQLLSIALNGMTKFRTRILPQLLTYQQQKGQLPPRLTFALAALIAFYRGEREGQTYPLQDDAHWLERYSTLWNGVKHGDIALAELVNRVLSDANHWGQDLTAVPQLANQVTEQLQTILSRGMRAAVAAYS
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: RSMH_LEGPL
Sequence: MAKHQSVLLHESIKGLAIKADGIYFDGTFGRGGHSREILNHLSDKGRLFAIDKDLDAVQYAKDYFGLDKRFQIFHGSFAQIKEFASQAGVIGAVDGILLDLGVSSPQLDNPERGFSFMLQGPLDMRMDLTQSINAANFVNEAEVNELAHVFRAYGEERFAGRIAKAIVDARKLKPITTTLELAEIVKEANPKWEKHKHPATRVFQAIRIHVNQELTDLSNCLEQCLDVLGPGGRLAVISFHSLEDRIVKQFMRDKEQGNRPPVEVPIKYEELKTNFKKVGKAVKPQSSEIKENVRSRSAVLRIGEKLA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.