PharMolix/UniProtQA huggingface dataset:
Protein: DRC7_CHLRE
Sequence: MAEGIGTFGTLSRDVLEERLMEARRTYRLNMGYAGLKQLPPGFVELVKKYNPHITELELSSNDLTDLPDELEEFRYLRILRLKYNQLKRIPAVVYRLPQLMVFDASGNRIQKVDDAIGHLSLLKELDVSGNEITTLPESLSTLPKLEVLQVENNRLELLPESLGELPGVIKMDLSTNNLRYLPASMGQLKKVQRIDVGNNLLTKVPPSMGHLKTLKEFNLRYNHLDDRYKAKVEEGLSKFLAFLREEEERERLEEIERLKPIGTPVGAYLEYRCKAEVGQVVKTDMGETTVDNRCWIRTGHTLTQVGSMLLIFGGQLQKDGSTTNDLFWMTMDRMEWHNQPCKGEKPPPRYNHAACYDEENNRLVVFGGRTAERKRLNDIYFLDLDSWTWFKPSTEGTAPTPREQAVATFWAGSMVLFGGHAIGGRTNDLFLLDLGAWQWSQPAFSGTAPSPRQACALCIGHGNLLFVHGGRNNFVLEDLHVMDFVSKNWTEIPCEGRVPPPRHSHRITVHRDQLYLLGGLDELGAQSVAMYRVALPAGQQDTYATSKPKWVEWDSELPYNKNRTATLWNGTISIYQLGSNTLGRVNDDDAEKGLDELRPKNAKRMRVQHTINTAGKMPRSFTQHSAHEARVLQYVQDFQRIFEELYPYRRPLYLTPRNECGVPKFVCTSLRPSQLVYTELYDLDGASQFVADFLSYEPLEDPLHPPDTLPSPMSALEWRAGDSFDMATVLASMLLGVGYNAFVVLGYAPGPVVQNDQRNTDLAATRTGAGAEEEEESGPCKFVHAWVMVLPGKREVTEAMFIEPSAGRKDVSYDLSDPTKWEPVFEDRGMRSRADGNADESETEGGGGLDDGEGVEAEVVPDIPPSWVPKLTIPRDAFDMRCPRHEIFARFGDCSRWDGMVERLVLYADEERTVVTEIRETFTRRRDKLRERRVYPQKDTTIEHFNRGSVFALKDILTVKNDRRGRKVIQYYTGRDDRLIYISATYAVDPLAPRPQPSALLEEYSSLLVAEKDCLQWVRDGEWEISEIIRTRTNQEQNITLETPYYDIVRIKAEESEEVREKALKALKDRLIERANIIQARLDEESAALAKRQQTFHRDRDQMSAAEEEDYERQTEESMFRIHILERRLRRHEEQALHKYYELDAKLRADGRLAALLN
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337).  Involved in the regulation of flagellar motility (PubMed:21289096).
What are the official names of this protein?
Dynein regulatory complex subunit 7, Coiled-coil domain-containing protein lobo homolog, Flagellar-associated protein 50.
What is the protein family that this protein belongs to?
Belongs to the DRC7 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Associated with the outer doublet microtubules (OD).
Protein: RBS_XANFL
Sequence: MRITQGTFSFLPDLTAAQVKAQIQYALDQNWAVSVEYTDDPHPRNTYWEMWGLPMFDLRDAAGVYGEVEACRTAHPGKYVRVNAFDSNRGWETVRLSFIVQRPEKEDGFRLDRTEGPGRTQRYALQHRSYAAG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
Protein: LPXD1_FRATH
Sequence: MQYTLKQISEHLNAKVINEPSGEVIITGLNYAEQAKENDLTLIDKQEHIKLWQNSKAAAAIVSKKISKELAQVNDKPLIVVNNADLAMAKILELFSVPYPEQNGIHEKAVIDPTAKIGKNVSIGPGAYIGKNVEIGDNTIIYANVCIYNDAKVGTNCIIWPSVTIRDRTIIDHFCRLYSNCSIGSDGFGYRPSEDGRTIVRIPHIGNVVIGSFVDIGSNTCINNAKYGSTIIGDYTKIDNLVQIGHNVIIGKGCMICGQAGISGSVTIGDGVIIAGNAGIKDHTNIGSDARIGGKAGVMWDVPAGESHMGYPAYKDSELAKQWIAIRKLPETMKKLKAIAKSLNIDL
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: XYNB_DICB4
Sequence: AKKTILDLKD
What are the official names of this protein?
Endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: EFP_BIFLS
Sequence: MAQTTNDIKNGSVLNLDGQLWTVMKFQHVKPGKGPAFVRTTIKNVLSGKIVDKTFNAGMKMEFETVDNRTLQYSYEDGDNFVFMDMTTYDQIMVPKTLLGDKAKFLLEGTDCLVSFHDGTPLSVDLPGSVVLTITHTEPGLQGNRSNAGTKPATVETGAEIQVPLFINEGDRVKINTEDGSYTGRENN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAP_NEUCR
Sequence: MNGRPSVFTSQDYLSDHLWRALNA
What is the function of this protein?
Arginine attenuator peptide (AAP) that has a regulatory role in the production of arginine-specific carbamoyl phosphate synthetase.  Encoded by an upstream open reading frame (uORF) within the 5'-leader region of arginine-specific carbamoyl phosphate synthetase small chain (arg-2) mRNA, it attenuates the translation of the downstream arg-2 ORF.  In the presence of high concentrations of arginine, ribosomes translating the uORF encoding AAP stall at the termination codon, resulting in reduced translation from the downstream arg-2 initiation codon.
What are the official names of this protein?
Arginine attenuator peptide, AAP, Arg-2 leader peptide.
What is the protein family that this protein belongs to?
Belongs to the arginine attenuator peptide family.
Protein: IHFB_ECOUT
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PET1_PETCR
Sequence: GVQKTVVEAPSTVSAEKMYGFLLDMDTVFPKVLPQLIGKSVEILEGDGSVGTVKLVHLGEATEYTTMKQRVDVIDKAGLAYTYTTIGGDILVEVLESVVNEFVVVPTDGGCIVKNTTIYNTKGDAVLPEDKVKEATEKSALAFKAVEAYLLAN
What are the official names of this protein?
Allergen Pet c 1.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: MATK_BANCU
Sequence: MEELQEYLKIEKSWQQDFLYPLFFQEYIYTLAHDHGLNRSILYESAENLGYDNKSSSLIVKRFIDRMYQQNHFIISSNSNSSNQKKFLGHNKNLDLKIISEGFAVIVEIPFSLRLVSSLEGKELVKSCNLRSIHSIFSFLEDKFSHLNYVSDILIPHPIHPEILVQAFRVWVQDVPSLHLLRFFLYEYRNWNSLITPKKSIYTFSKENQRFFLFLYNFYVYKYESMFVFLRKQSSHLRSTSFGALLERTHFYGKREHLVVLFRNDFQSTLCLVKDPFIHYVRYQAKSFLAARGTPLMMNKWKYYLVNFWQSYFYFWSQPGRIHINQLSNYSLDFLGYLSSVRLTFSVVRSQMLENSFLIDIAIKKFDTIVPIIPLLGSLAKAKFCNALGHPISKPVRTASSDFDIIDRFGRICKNLFHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSELFEEFFTEEEEVLSLIFPRASSPLRRLYRERVWYLDIIRISDLVNHD
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SNURF_MOUSE
Sequence: MERGRDRLHLRRTTEQHVPEVEVQVKRRRTASLSNQECHLYPRRSQQQQVPVVDFQAELRQAFLAETPRGG
What are the official names of this protein?
SNRPN upstream reading frame protein.
What is the protein family that this protein belongs to?
Belongs to the SNURF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TY51_PITHY
Sequence: FPPWL
What are the official names of this protein?
Tryptophyllin-5.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KRP7_ARATH
Sequence: MSETKPKRDSEYEGSNIKRMRLDDDDDVLRSPTRTLSSSSSSSLAYSVSDSGGFCSVALSEEEDDHLSSSISSGCSSSETNEIATRLPFSDLEAHEISETEISTLLTNNFRKQGISSSENLGETAEMDSATTEMRDQRKTEKKKKMEKSPTQAELDDFFSAAERYEQKRFTEKYNYDIVNDTPLEGRYQWVSLKP
What is the function of this protein?
Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity.  May target specifically CDKA-1.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 7, Inhibitor/interactor of CDK protein 5, KIP-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the CDI family. ICK/KRP subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Homogeneously distributed. Accumulates strongly in vegetative cell nuclei immediately after asymmetric division and disappears later.
Protein: NU6M_CEPCO
Sequence: MTYFVVFLGLCFVLGGLAVASNPSPYYGVVGLVLASVVGCGWLLSLGVSFVSLVLFMVYLGGMLVVFVYSVSLAADPFPEAWGDWGVVGYGASFVVVLMVGGVIGGFVGGWDFGVVTVDSVGVFSARLDFSGVAMFYSCGVGMFLVAGWGLVLTLFVVLELVRGLSRGAIRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: Y040_CALS4
Sequence: MAKGGFPGGFNINNMIKQAQQMQEEIKKMQEELMQKTVEGTSGGGMVKAVANGRKELVSININPEVVDKDDVETLEDLVLAAVNQALRNAEEMIASEMAKITGGFNIPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein TTE0040.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SCTG_SALTY
Sequence: MKKFYSCLPVFLLIGCAQVPLPSSVSKPVQQPGAQKEQLANANSIDECQSLPYVPSDLAKNKSLSNHNADNSASKNSAISSSIFCEKYKQTKEQALTFFQEHPQYMRSKEDEEQLMTEFKKVLLEPGSKNLSIYQTLLAAHERLQAL
What is the function of this protein?
Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:9680224, PubMed:9786184).  Pilot protein that is required for the proper localization of the secretin InvG/SctC in the outer membrane (PubMed:9680224, PubMed:9786184).  Required for the secretion of the Sip virulence factors (PubMed:9680224, PubMed:23159244).
What are the official names of this protein?
SPI-1 type 3 secretion system pilotin, Invasion lipoprotein invH.
What is the protein family that this protein belongs to?
Belongs to the InvH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MURJ_THEMA
Sequence: MSSIKKTLAFSLGTFFSRITGLVRDIILAKTFGASSTLDAYYVSIVFPFFLRRTFAEGAMSSAFMAIYKKLKNKEEKAQFTSAVLTSLGLVTLLIVFLSEVFPYFMASIFATGADEEVKSLAADLIRLTAPFITIVFVWAVFYSVHNASHRYFLPALTPMFSNVGVIVGCLFGDVRWAAAGFTIGGLAALLVLLPFGKFRYRPTFKGLGEFYRLFFGTFMTMAVSQVTTLIDVNVASFLDPGSLSLIQLSSRLYQLPLGIFGVAVSTVALSTLSESEGDFHENLKDFISKSLFLTLPSSIGLMALSERIISLLFGYGAFTHEDVKKSAQILFMYAIGLCFVSLFNLLSRAYHASKEVKTPFFATLLVSAVNISLDVILGFTMGASGIALATSVSYIAGFVFLTLRMKPSFDKKIFKISLASAVMGTVILLLRGSFKGNLGTIFLVLIGVFVYVLFSKLLKIEELEEILRRGSH
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPN14_YEAST
Sequence: MTKTITVAHIQYDFKAVLEENDENDDEFYINVDKNLNEIKEHKIVVLGNSRGVDAGKGNTFEKVGSHLYKARLDGHDFLFNTIIRDGSKMLKRADYTAVDTAKLQMRRFILGTTEGDIKVLDSNFNLQREIDQAHVSEITKLKFFPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLDGTIRLWECGTGTTIHTFNRKENPHDGVNSIALFVGTDRQLHEISTSKKNNLEFGTYGKYVIAGHVSGVITVHNVFSKEQTIQLPSKFTCSCNSLTVDGNNANYIYAGYENGMLAQWDLRSPECPVGEFLINEGTPINNVYFAAGALFVSSGFDTSIKLDIISDPESERPAIEFETPTFLVSNDDEVSQFCYVSDDESNGEVLEVGKNNFCALYNLSNP
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.  Is not a genuine component of the 26S proteasome, but an auxiliary factor that interacts with the proteasomal ATPase of 19S regulatory particle (RP).  Acts as a chaperone which regulates the highly structured assembly of the 19S regulatory particle.  Involved in the substrate specificity of the 26S proteasome and is especially involved in the degradation of ubiquitinated GCN4.  May contribute to the stability of the 26S proteasome in some stress conditions.
What are the official names of this protein?
26S proteasome regulatory subunit RPN14, Proteasome non-ATPase subunit 14.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PAAF1/RPN14 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PP914_SOYBN
Sequence: MVKCFDFFLSLNFGKMTKLLVWRTDKPQDDMPQTPNSQVTIVSRDHPRGGNY
What is the function of this protein?
Produces a rapid alkalinization of the cellular media and the induction of defense-related genes, including chitinase 1b, chalcone synthase and CYP93A1.  Not active in tobacco or Arabidopsis.  The receptor for GmPep914 is probably different from the receptor for GmSubPep.
What are the official names of this protein?
Protein PROPEP914, GmPROPEP914.
Protein: MAB6B_HUMAN
Sequence: MPRGQKSKLRARGKRRETHDQPQGLTGPQATAEKQEESRSSSSSSAVCQGARRRSSGSSVPQESQGASPTGYPDAGASCSKYDVAAMGQDEKSPSTSRDASVSQESQGASPIGPPDAGISCSKSDEAAKGQNEKSPSTSRDASVPQESQGASPTGSPDADVSGSKSDVAAKGQDEESLSSSKRAAFFTTTDGDPIKRKANKMVQFLQKKFEKKEPILKADMLKRLRRQYKPCFPEILKRTSEHLTVFFGVELKETDSSGESYTLVSKLGLSNEGSLSGDNALPKSGLLMSILGLIFMRGNRATEEEVWKFLGLLGIYDGILHSIYGDARKIITEDLVQDKYVVYRQVCNSDPPCYEFLWGPRAYAETTKMRVLRVLAEINNTSPGLYPHLYEDALTDEVERALRLRA
What are the official names of this protein?
Melanoma-associated antigen B6B.
Protein: LIPA_RICTY
Sequence: MTNVNRRPDWIKVKAPNSAEYYNTKDLIKNLRLNTVCEEAACPNIGECWSRKHATVMILGSVCTRACRFCNVKTGRPDLLDPHEPRRLAEAVQKLNLNHVVITSVDRDDLEDGGASHFAECINEIRRSSPNTTIEILTPDFLRKAGAVEVIANSKPDVFNHNVETVPSLYKTIRPGARYYNSLSLLHNIKKLSPEIFTKSGMMVGLGEEINEVVQVMDDLREANVDFLTIGQYLQPTKSHAEVIKYVTPEEFKYLERIAKTKGFLMVSATPLTRSSYHADKDFQKLKENYNIRLASM
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_BACCZ
Sequence: MMVKVASITKLEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDTPASCAAVYTTNQIQAAPLQVTKDSIATEGKLQAIIVNSGNANACTGMKGLQDAYEMRALGAEHFGVKENYVAVASTGVIGVPLPMEIIRKGIVTLIPAKEENEAHSFSEAILTTDLITKETCYEMIIDGKKVTIAGVAKGSGMIHPNMATMLSFITTDAHIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIAMASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGAQTNEEAKKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIDITLQSIVVLKNSEPQMFSEEEMKMRLQEHEIMIDVYLHLGEETGSAWGCDLSYEYVKINACYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALR_RAT
Sequence: MLLSVPLLLGLLGLAAADPAIYFKEQFLDGDAWTNRWVESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDEDDRDEDEDEEDEKEEDEEDATGQAKDEL
What is the function of this protein?
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle.  This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER.  Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity).  Involved in maternal gene expression regulation.  May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity).  Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
What are the official names of this protein?
Calreticulin, CALBP, CRP55, Calcium-binding protein 3, CABP3, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface. Sarcoplasmic reticulum lumen. Cytoplasmic vesicle, secretory vesicle, Cortical granule. Cytolytic granule. Note=Also found in cell surface (T cells), cytosol and extracellular matrix. During oocyte maturation and after parthenogenetic activation accumulates in cortical granules. In pronuclear and early cleaved embryos localizes weakly to cytoplasm around nucleus and more strongly in the region near the cortex (By similarity). In cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation (By similarity).
Protein: PYRD_ACIBY
Sequence: MLYSLARPMLFSLAPERAHELTLSMLDKAHKLGMMRQTVEAKPTTCMGIEFPNPVGLAAGLDKNGAHIDALAGLGFGFIEIGTITPRPQSGNPKPRLFRIPEAKAIINRMGFNNDGVDKLIENVKASKFRGILGINIGKNADTPVEKAVDDYLICLEKVYNYASYITVNISSPNTKNLRSLQSGDALTELLQTLKARQLELAEQYNHYVPLVLKVAPDLTAEDVEFISAQLLDFKIDGLIVTNTTLSREGVENLPYGNESGGLSGAPVFEKSTECLRLFAQTLKGQIPLIGVGGILSGEQAAAKQQAGATLVQIYSGLIYTGPTLVKQCVEAMT
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPB_CALFG
Sequence: MRINPTTSGPGVSTLEEKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVHGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYEIAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TBP1_ENTH1
Sequence: MSTPGDFSLSPFILGGAVDPRSMSQLGNICHADYMSTSTESQERSLNNPNDTHPEIVNVVSTFQLGVKLELRKIVQKARNAEYNPKRFAGAIMRISSPKSTALIFQTGKIVCTGTRSIEESKIASKKYAKIIKKIGYPIHYSNFNVQNIVGSCDVKFQIALRTLVDSYLAFCQYEPEVFPGLVYRMASPKVTLLVFSTGKVVLTGAKDEESLNLAYKNIYPILLANRKEDISNQ
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein 1, EhTBP, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: ACHB3_RAT
Sequence: MTGFLRVFLVLSATLSGSWVTLTATAGLSSVAEHEDALLRHLFQGYQKWVRPVLNSSDIIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDQKLRWNPEEYGGINSIKVPSESLWLPDIVLFENADGRFEGSLMTKAIVKSSGTVSWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRREGFYSYPFVTYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSSTYHPMAPWVKRLFLQRLPRWLCMKDPMDRFSFPDGKESDTAVRGKVSGKRKQTPASDGERVLVAFLEKASESIRYISRHVKKEHFISQVVQDWKFVAQVLDRIFLWLFLIASVLGSILIFIPALKMWIHRFH
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-3/CHRNB3 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: UPPP_METM5
Sequence: MEELILGIVQGLTEFLPISSSGHLAIFTAIFNSTPDVGYFAFLHLATFLAVLIFVKSEVFEIVNGISKKDNEYINLASKLVLSTIPAVIVGLCFGDFIESVFSSTFLIGVFLSITGILMLLSDKLNQNLKTIKSIPYLDAMIVGIFQAFSVLPGISRSGTTLFAALFLGMKKEDAVKYSFLMGLPVTFGAGILELQKVSFSAEQLFGFVISFLTGLLGLYLVKKMVIGGKLKIFGYYCFLASFFVLMFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
What are the official names of this protein?
Undecaprenyl-diphosphatase, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS17_HALHL
Sequence: MSEEKNTRTVNGRVVSSKMDKTLTVLVERRVKHPLYGKFIRRSTKLHAHDEGNEGREGDWVSIQECRPLSKNKTWRLVKVLERAAS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: KCY_BURM1
Sequence: MKSTRPFHPTPVITIDGPTASGKGTVAALVAAHLGFHLLDSGALYRLAALASMRYDIAAEDVDALVKLIDDLHITFREGCAQLDGVDVSNDIRAEAVGNRASAIAVHGPVRTALVARQRAFRKTPGLVADGRDMGTVIFPDAMLKVFLTASAEARAARRHKQLMQKGFSANIDDLLRDLRERDARDSNRAAAPLKPAADAKLLDTSALSVDEAVDQVLQWYRALGQPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.