PharMolix/UniProtQA huggingface dataset:
Protein: AROD_ECO8A
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADHSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: RL3_METFK
Sequence: MSLGLIGRKVGMTRIFTDEGESVPVTVLEVVPNRVTQIKTAASDGYTSLQVAYGERRASRIGKALAGHYAKAGVSAGAGIKEFPVSDDVLANYSVGGQITVELFQPGQLVDVTGTSLGKGFSGAIKRHNFSSNRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMPGHLGAVKTTVQNLEIVRVDAERNLLLIKGAVPGSKGGDVVVRPSVKVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PCTM_STAAU
Sequence: MKKDEYIKLHQSYLNEYIKFADAKALAIISINGFILNFNFSKRNIKFHNTEDIFNFTAFILLIITIILAAFAVYPRTNNRSEKGIIFWDNINSMGEKEFIEKVKFEKEEELLEKTIQQNYFLAKTASMKYSIIRKVFIISALGYSCLLFSSIFQIICS
What is the function of this protein?
The effector gene of a two-gene Pycsar system.  Expression of this and adjacent SaPycC cytidylate cyclase (AC P0DV38) probably confers resistance to bacteriophage.  The genes are probably only expressed in response to bacteriophage infection.  Probably only responds to cCMP (produced by its cognate NTP cyclase), acts by impairing membrane integrity.
What are the official names of this protein?
Pycsar effector protein SaPycTM, SaPycTM.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLGH_XANC5
Sequence: MSRLPSLSRLCLAIACSALLGGCVAAGDVRPFAELAPIVPVVAPVAQPTAGAIYAAGPSLNLYGDRRARDVGDLLTVNLVESTTASSTANTSISKKDATTMGAPTLLGAPLTVGGLNVLENSTSGDRSFAGKGNTAQSNRMQGSVTVTVMQRLPNGNLVIQGQKNLRLTQGDELVQVQGIVRAADIAPDNTVPSSKVADARIAYGGRGAIAQSNAMGWLSRFFNSRLSPY
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: THII_METTH
Sequence: MILDYDVILARYGEVAIKGPSVRRRFEGKLLHNIKSAFSCRAELRHGRIFIFPEDMDEALDRLSKIFGIVSFSPAVTAETGFDSIEDSLREYIHELRSEGLLTSRTPFAIRCRRVGEHDFTSQEMAAFAGSVVVGEIGAPVDLGNPDLEIHLEIREDETYIYHRVIPGPGGLPAGTQGKVVALLSGGIDSPVATYLMMKRGCQVVAVHMDNAPFTGEEAEEKVEKIAAKLAEYSAGVEFKLRTFSYGRYLESCRRGAPEKMTCVLCKFGMYHLAEMVAEEEGALAIVDGSSLGQVASQTLPNILATRMGVNIPILSPLIGMDKVEIENLAKRIGTYDISVIPDGGCSAVPAHPSTASPPEAVMEASEKINVKEEVAEIFRKGSKTRIFS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DKF2_CAEEL
Sequence: MDANDYPRLYYTSMPSSSTSMVTTTRFSTSFSPSIPCHRQENFRRHSTSALAKRNGSESEKSAEIRENPDEIEVSRVSGRDSSLAFYTTAHETSSMLSRDSRDETLTPNEHIHQASSRRVSANDSVFEDGYVDFVDEPREHGSRRKSFEKFTDRNGEEKEGRVFELSTPQPTREAAPGAHQFQLPTLLVTSTPTTVFDHSDDEVWTPYRPPPNREYSSSSEPMMGDLTFRLQSGIHKKSIAVEGTEIALRDLRNEALQFIKEIYPEKGCSSLEDYILLYKHDLRSINILQLITTSSDVTDGTLVEVVIGSCPQNERIVVHPHTLFVHSYKVPTFCDFCGELLFGLVKQGLKCFGCGLNYHKRCASKIPNNCNGSKQRRPSAIPLSPSNSNILNLNERRHSRRESCLEALDAARPSSTLGGAATPNIFITSDDCGDAVGGNYLQMPRKDRSCSWSGRPLWMEIAEATRVKLQVPHTFQVHSYKLPTVCQHCKKLLKGLIRQGMQCRDCKYNCHKKCSEHVAKDCSGNTKASQFFLGSQADDGASEDRDDDLSLRSGSGAHKKAQNTPSAPLQGSEGSGSPGPVVSFAANALSNMPDDDVISSESANIPLMRVVMSKKQTKRKNNKLLKEGWIVHYTDQQNMRKKHYWRLDTKGITMYQDENTTRYYKEIPLNEILNVSMSPPDKTADYLFEIRTGVCVYFISGSPSDEKGSSLDAQSWTTAIQSALMPVTPQSSVVGGKRIDKLKVPTEGETGHLGAKIQTEHEFSQLYQIFAEEVLGSGQFGTVYGGIHRRNGQHVAVKLIDKLKFPPNKEDLLRAEVQILEKVDHPGVVHFMQMLETTDRIFVVMEKLKGDMLEMILSSEKGRLSERTTQFLVAQILEALRYLHHLNIVHCDLKPENILLNSNSDFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGFNRSLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAEFMYPPTPWKEISENAIEFINGLLQVKMSKRYTVTKAQSQIWMQNYTLWSDLRVLEKAVGQRFVTHESDDVRWQAYEKEHNVTPVYV
What is the function of this protein?
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC.  Acts in the intestine to regulate both innate immunity by promoting activation of PMK-1 and also stress response and life span by acting as an upstream, negative regulator of the daf-16 transcription factor.
What are the official names of this protein?
Serine/threonine-protein kinase dkf-2, D kinase family-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Translocation to the cell membrane is required for kinase activation.
Protein: DCHM_BPT4
Sequence: MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHISKKDYVGKYA
What are the official names of this protein?
Deoxycytidylate 5-hydroxymethyltransferase, Deoxycytidylate hydroxymethylase, dCMP hydroxymethylase, dCMP HMase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: PHS_NATPD
Sequence: MSDRLTDDEIQAQLPAAWDRDGDEIVRTFEFESYLEGVGFASAAGGLAEEAFHHPEMTIGWREVEVRLTTHDAGGITQKDIDLAERFDELAE
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: NUSB_CAMFF
Sequence: MATRHQVRQSVVSLLYANEMGSEMEEFSNEFLEEKKIRNDQKSFTLTLYNGVLDNLNLIDEALDAHLGKWKLGEIGAVERAILRLGAYEIKFTNTQSAIVINEAILLANELGSDSSTRFINGVLDAISKVN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: DCD_PSEPF
Sequence: MSIKSDKWIRRMAQEHGMIEPFVERQVRGSDDSRVISYGVSSYGYDVRCTNHFKVFTNINSAIVDPKNFDAGSFVDVHSDVCIIPPNSFALATTVEYFRIPRNVLTICLGKSTYARCGIIVNVTPLEPEWEGQVTLEFSNTTNLPAKIYANEGVAQMLFLESDEECEVSYKDRAGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TMCO3_HUMAN
Sequence: MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTLLMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGMLVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKYLIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVVTEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLWRAAITRCVPRPERRSSL
What is the function of this protein?
Probable Na(+)/H(+) antiporter.
What are the official names of this protein?
Transmembrane and coiled-coil domain-containing protein 3, Putative LAG1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAJ_XANCB
Sequence: MSKRDYYEVLGVARGASDEELKKAYRRCAMKYHPDRNPGDAAAEATFKECKEAYEVLSDGNKRRAYDAHGHAAFEHGMGGGGGGPGGPDMGDIFGDIFGNIFGGGAAGPRAARRGADVGYVLELDLEEAVAGIERRIEIPTLIECEPCHGSGSEDGKVEVCATCHGRGQVRIQRGIFAMQQSCPHCDGRGTLIQNPCKTCHGAGRVEEDKVLSIKVPAGVDTGDRIRLAGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTADQRELLKQFEATFTGEDARKHSPKSATFIDGVKGFWDRMTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BREBN
Sequence: MAISAQAVKELRERTGAGMMDCKRALEETAGDMEKAIDLLRERGVAKAAKKSGRIAAEGLTATAVAGNVAAVVEVNCETDFVGKNPEFQTLVKDIAEHVVSQRPASVEEALEQPFKGAGETLGHVINEKIATIGENISFRRFALSEKTDNGVFGAYLHMGGRIGVLVTLEGTQDETLARDLGMHAAASNPRFANREEVSADEIEREREVLKNQALAEGKPANIVEKMVEGRLSKFFEEYVLVEQPFVKDTDKKVAVLLKEAGATLKGFARFQVGEGIEKKQEDFAAEVMAQVNKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_SOLUE
Sequence: MPIVIRNGRVIDPASNTDRVADVFIVDGRIAGVAPNLSSPKAEVFDATGMIVAPGFIDMHVHLREPGFEHAETIESGSRAAAAGGFTSICCMPNTKPVNDSAMVTSYIVEQARSKAAVNVFPIGAITKGSAGEELAAIGAMKAAGAVAISDDGLPVMNARVMRRAMEFARSYDLPIIQHCEDLNLSAGGDMHEGANSVRWGLRGIPAASEDVMVARDLVLAQLTGARYHVAHISTRNAVAMVEYGRSHGLPVTCETTPHHFGLADADMAPYDSNYKMKPPLRSCGHRDAIIEGLIAGTISAIATDHAPHPGSEKMQEFERCPFGIIGLETALALALEELVAPGKITLARLIELFTTGPESVMRLGRGTLTPGAPGDVTVFSPTVEWTYDVNQSASRSRNSPFHARTFHGGPMATIVNGGLKWSRQSSHIT
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: SYD_ECOL5
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILERTGAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADM_PYRAR
Sequence: MVRGLFPGRFQPPHWGHIYAVKEILKEVDEVIIAMGSAQFNYLLKDPFTAGERIWMLREGLREGGVDLSRVVIIPIPNVENNLEWLGRVKSYTPPFDVIYTGNPFVALLFREAGYEVRQQPMFQRERYSSTRVRELLLRGDPSWEELVPKSVAEIIKKLRGAERIKTAASGEAEPHKW
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_CAUSK
Sequence: MLIRHAPDLTDNDVTGHGLYLRRRDFIGGAAGLGLMAAAGSASARGLTYGPGFSTTEAPTPKKDITSYNNFYEFGVNKEDPSENAGSLKTRPWTVRVDGECEKPATFAIDDLIKGNKLEERIYRMRCVEGWSMVIPWVGFPLKDLIAQVKPTSKAKFVAFETLMRPSEMPGQRWDTLQWPYREGLRIDEAVHPLAILAVGLYGDVLPNQNGAPLRLVVPWKYGFKGIKSIVRISLVETMPATAWNVLAPREYGFYSNVNPAVDHPRWSQATERRIGEFRRRETLPFNGYGQYVADLYRGMDLKRNF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: Y661_METTH
Sequence: MMLNSGDTAWMLISTALVILMTVPGVAMFYSGLTKRENVLNTIFLSFVSLGIVSLLWFLFGYGLIFGGDVSGIIGSHQVGISLINLGSASKYAPTIPEGLFAIFQMTFAAITVALISGAVVERIKFSSWILFIPLWFALVYVPVAHWVWGGGFLQNLGVHDFAGGIVVHITSGIAALALALVTGPRYDQKLMPHHLGYSVIGTGLLWFGWFGFNAGSALSAGSLAANAMIVTNTSAAAGMIGWILMDRLKTGKPTLLGALSGAVAGLASITPAAGFVDIGASIVTGLVAAVICYLAVSWLKPAAGYDDALDVFGIHGVSGIIGTLGVGLFAVPALNPSLTSGGLLTGSTSLLVSQLIGVVTVTVYTFVVTYILAMLLMKFKGLRVEREEEIQGLDINLHEETGYRLT
What are the official names of this protein?
Putative ammonium transporter MTH_661.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: XYNA_PENCH
Sequence: MIPNITQLKTAALVMLFAGQALSGPVESRQASESIDAKFKAHGKKYLGNIADQGTLNGNPKTPAIIKANFGQLSPENSMKWDATEPSQGQFSFAGSDYFVEFAETNGKLIRGHTLVWHSQLPSWVSSITDKTTLTDVMKNHITTVMKQYKGKLYAWDVVNEIFEEDGTLRDSVFSRVLGEDFVRIAFETAREADPEAKLYINDYNLDSATSAKLQGMVSHVKKWIAAGVPIDGIGSQTHLGAGAGAAASGALNALASAGTEEVAVTELDIAGATSTDYVDVVNACLDQPKCVGITVWGVADPDSWRADESPLLFDASYNPKEAYNVSQLLSRQHAFDLYLKLGNLLLSRLHSD
What is the function of this protein?
Hydrolyzes oat spelt and birchwood xylan randomly, yielding xylose and xylobiose as major end products.
What are the official names of this protein?
Endo-1,4-beta-xylanase, Xylanase, 1,4-beta-D-xylan xylanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_STRPB
Sequence: MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOA_CYCTA
Sequence: MIRDEISVSTQTPRWRCIGSGADSKRLHYGRFALSPLRKGQASTIGIAMRRALLGEIEGTCITHAKLEKVTHEYSAIIGIEESVHDILINLKEIVLRSDPYGTREASICIVGPRNVTAQDIILPPSVRIIDATQHIASLTKSITFDIRLWIEKDRGYRIQSPKNYQDGIFPIDAVFMPVRNANYSIHSYGNGNDIQEILFLEIWTNGSLAPREALYRASRNLIDLFIPFLRAEEQNIDGMDNQNGSNMPSFSFSNISADMERMEEEVAFKHIFIDQSELPPRVYNCLGRVNIHTLSDLLNYSQEDLMRIGHFGKKSVEQVSEVLQKHFAVDLPKNKFQIH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BCN92_DROME
Sequence: MSTRRQAITLYRNLLRESEKLPSYNFRMYAARKIRDTFRANRSTRDFAEIDRQMAEGQQNLELIRRQVIIGHLYSADKLVIENKKTLKPSDD
What are the official names of this protein?
Protein bcn92.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FLIW_THEP1
Sequence: MVYKTKLGEMEISDESIFTFEKGIPGFEHLRKFALVFPQETFPIGWLLSLEDPEVGLPVVDPKLVRADYDPVVLSEDLEEIEAENQEALLFFCVLTIPPGKPEKTTINLRAPIILNQKKKKGIQTILENEDYQLRHLLSEEMERSKTVV
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LEGPA
Sequence: MFDESYSIKNFDDVLFKAISDEKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEFVDVAEELAISRAKLLFGAHYVNVQPHSGSQANAAVMMALLSPGDTFMGMALPHGGHLTHGSKVNFSGKLYHSVEYGVDSNTGLIDYDALEKLALQHKPKLIIAGFSAYSRILDWARFREIADKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGGLILCKENEEIEKKLNSSVFPGMQGGPLMHVIAAKAVAFAEALLPEFKTYQQQVLANARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAAVGRANITVNKNSVPNDPRSPFVTSGLRLGTPAATTRGFKEREITLLSNWVADVLDNVHDETNISRVKTQVLLLCREFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC23_CAEEL
Sequence: MNVSFSTPVQNSTASRLALIQQAAARSGALPPAGQYRGSKLSPFDVSQMSGVSISMVERAKINGPEFVEELEWLRQQTTSRCFLDAEMWTNEILAHLPDKWCAPNTLNLYNQVSELVLDNTRSPMASPASNSLYAPGEDQMPTVKRNHTSRFAQSLIKNKEFRRAAFFLEKTMNGNKLDHFLHFRCLFLAYYQEHLENDAEGIERKTSFAEERSPFSLLYQRMEDKKLRENEDVWFEYLMGLLEVELGLKDLAEKSFRNVVIREPRIWPAWEALSRLIADIEDADKFVTSAEVKSLWMGDWFMTLVLQRFHQHSMAIQKAEQLVTRGMTGLPMIITKIAACSNARHDHDQAISNFEDVRKADPYRLGDLHLLSDSLYIRNDQKKLSTLAIEVYKVHKFRWETCCIVANYHAIRRDSEHAIKFFQRALRLNPGLAALWVLIGHEFMEMKNNAAACVSYRRAIEIDPADHRGWYGLGQMYDIMKMPAYALFYYQEAQKCKPHDSRLLVALGDIYSKLNRIEDAEKCFTGAYLFGDVEGNALWSLAKLHERYSDDNKAAQAFEVFLVVYELVTSAEEKIIYAIAFLANHFFKIEDFDKASEYATKCLAFETLCQEGNRLFREIAKIQARESRLPVEEAPGPSNASAAGGQEAMDTEEAPQEGGEEEMSEGEDDFSF
What is the function of this protein?
Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:11861581, PubMed:15238519).  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (PubMed:11861581).  Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in germ cells (PubMed:11134076, PubMed:11861581, PubMed:15238519).  Required for embryonic anterior-posterior axis formation (PubMed:11832245).  Plays a role in regulating the abundance of glr-1 receptors in postmitotic neurons, which may in turn control animal locomotion (PubMed:15556870).  Involved in regulating GABA neurotransmitter release at neuromuscular junctions in GABA motor neurons (PubMed:24321454).
What are the official names of this protein?
Cell division cycle protein 23 homolog, Anaphase-promoting complex subunit 8, APC8, Metaphase-to-anaphase transition defect protein 3.
What is the protein family that this protein belongs to?
Belongs to the APC8/CDC23 family.
Protein: THIC_CAMJD
Sequence: MKTQMNYAKEGVFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQIGAKDFLDVVYHHAKSGVDFMTIHAGINSRATHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGVQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DGOT_ECOL6
Sequence: MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG
What is the function of this protein?
Involved in D-galactonate metabolism (By similarity).  Catalyzes the proton-dependent uptake of galactonate into the cell (By similarity).
What are the official names of this protein?
D-galactonate transporter, D-galactonate/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.