PharMolix/UniProtQA huggingface dataset:
Protein: TOP6B_METMA
Sequence: METPIAEELAKKQKSISVAEFFEKNRQILGFDSAPRSLITTVKEAVDNALDACEEAGILPDILVQVERTGPDYVTVIIEDNGPGIVREQIPKVFAKLLYGSRFHALKQSRGQQGIGISAAVLYAQMTAGRHTKILSKTSPTAPAHYYELMINTSTNEPDILVDEVRDWFRPHGTQIELEMRAAYVKGRRQSIYEYLKATAIVNPHARITLIDPDGNEEVFERATDKMPEPAEEILPHPEGIELGTLMKMLHYTERQKLAPFLRYSFCKIGLLTAEEICKAAGLDPEIDPHALGRHEARKLIEAFEKVKIMAPPTDCLSPIGEDLIYRGLEKETTVDFIATSTRKPAVYSGNPFVVEVGMAYGGNLPKEEKISIMRFANRVPLLYQQGGCVTTHAVEDIKWKQYGLNQPGGGIPVGPVILLIHVASINVPFTSESKDAIADIPVIKEEIDLAIKEVARKLKHYLSKQSNLKKRREKEIIITKVLPKLAAKVAHVLEKDVPDINPVVAKIMGNLLVHRVIKNNGDGTVDVAIKVKNFGTSAYSFRVHEMLPCKVSGAKPEPKVVTMGNDYDYVWDISASAGSSKVLSYKIESASEEELQKLPQLIVEGIEEELVTGAKAFKGV
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: TCPD_PONAB
Sequence: MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVASQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein: HISZ_MOOTA
Sequence: MASNLPLQLPAGVSDLLPPEAAALRQLEQRLLNCFRSWGYQEVMTPTFEFATTFQAGSPAGEEGALYKFIDRQGRVLALRPEMTAPIARLVATSLRRRELPLRLGYSARVFRYEEPQAGRRREFHQAGVELIGAGGVAGDVEIIALAVESLAQAGLEDFRLGLGQVAVTKGVLQDLALPPEAVAGIKSALASKDLVALERIYDEYHLEGERRRRLELLATIHGGREALEEARACFGRTAAAASLAELSRVWEALGAAGLEKWLFIDLGILRDFDYYTGIVFEGYVPGLGAPVCGGGRYDGLLAQFGYPCPATGFALGLERLLLARGETAPASLAGGYLVAGRDLAALLKRARELRSKGTAVVLDGESRSRQEAAARAAARGLNLEWIGE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_WIGBR
Sequence: MTNNKNYMKFLKFYNKKNKIKKIKNCSYKKLFCMNHYLRTGSNKRKKFLKKQYISTISVKKRLKCAWPKLINCSNFIIKDKKNIPLIKSYPKINRTSIAPTPWVIDSIFSFLKKFFFKKQNSKILSKNKKKKYLEKWEIVGIIRRYVFLILILSQTSIATYKLNSILPYKDISWSYTIYLFNKNIFLIIKYFSPYILQIFVLILFYILFFWVSASFWTAFMGFYQLITKKDEYNISNKSIVKEIKKNHRTAILMPICNEDVERVFAGLRATYESILSTGKIKFFDIYILSDSYNTDICMSEQKSWIDLCSETGFIGNIFYRRRNRRVKQKSGNIDDFCRRWGKNYSYMVILDADSIMSGKCLVKLVSLMESNPRAGIIQSIPKASGMNTLYARYHQFSTRVYGPLFTAGMHFWQLGESHYWGHNAIIRIKPFIKYCVLSPLPGNGIFSGSILSHDFVEAALMRRAGWSVWIAYDIPGSYEEPPPNLLDELKRDRRWCHGNLMNFRLFFMNGLHPVHRVVFLTGVMSYLSAPLWFAFLILSTILQIIYNIEFMCCFKINSYFYIIPYLHLEASIGLFFITLLLLLLPKFFSVILIISKNSIQYGGTRCFILSIILEIFLSMMFSPIKMMFHTFFIFRAFFGFSLSWKSPKRRDFSTSWKESIKSHIVQVVIGLIWSFLIIFFMTIKSLFIFFPIIFSLIISPLISVYSSYVKIGLIFKNFGLLLIPEEKYPPKEIINTKKYFKINKNKSLKNGFFQAILHPVYNALAVAMASSRHNSSILIDLNRKKFLDLILIKGLNKLNMIEKLTVLNDPIILTKLHFIYLLNNQ
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASNA_SALHS
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPFLPEQIQFVHSQELLSRYPDLDAKGRERAIAKELGAVFLVGIGGKLSDGHRHDVRAPDYDDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAG72_BISBI
Sequence: RGSNLTSLPLQNVIDLFYVGNITIG
What are the official names of this protein?
Pregnancy-associated glycoprotein 72, AmbPAG 72 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RK3_EMIHU
Sequence: MTAGIFGRKIGMTQIFDKDGSAIPVTLVKADPCQVCQIKTTKTDGYDAIQVGYLEEKLSKISKPIQGHLQKCGSTGYRKFGEFRVEDPETYNLGDQITTSAFSVGQKVRVTGTSIGKGFAGNQKRHNFSRGPMTHGSKNHRLPGSIGAGSTPGRVYPGKKMAGHLGNTKTTIKNSEILFVSEKENILILKGSLPGKAKNILRIAAKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL28_KOCRD
Sequence: MAAHCQVTGAQPGFGHSISHSHRRTKRRWNPNIQKKRYWVPSLRRNVTLNLSAKGIKVIDARGIDAVVNELIARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DDL_NOSP7
Sequence: MTKLRVGLLFGGRSGEHEVSIKSARAIAKALSVDENASKYEILPFYIQKDGRWLAGEAPQKVLETGSPLLEAEQSTSEGNLTSNPQVQTLSKWESPSQVAQVDIWFPVLHGPNGEDGTIQGLLTLMQVPFVGSGVLGSAMGMDKIAMKMTFEQAGLAQVKYKAITRAQVWSNPCVFPKLCDEIEAALGYPAFVKPANLGSSVGIAKVRSRQELEAALDNAASYDRRLVVEAGVVAREVECAVLGNDQPQASVVGEISYDSDFYDYETKYTEDRADLLIPAPIPDAIARQIQDMALQAFAAVDAAGLARVDFFYVEATQEVLINEINTLPGFTATSMYPQLWAHSGVSFPELVDRLIQLALERYSPS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL7_DERFA
Sequence: MMKFLLIAAVAFVAVSADPIHYDKITEEINKAIDDAIAAIEQSETIDPMKVPDHADKFERHVGIVDFKGELAMRNIEARGLKQMKRQGDANVKGEEGIVKAHLLIGVHDDIVSMEYDLAYKLGDLHPTTHVISDIQDFVVALSLEISDEGNITMTSFEVRQFANVVNHIGGLSILDPIFGVLSDVLTAIFQDTVRKEMTKVLAPAFKRELEKN
What are the official names of this protein?
Mite allergen Der f 7, Allergen Der f VII.
What is the protein family that this protein belongs to?
Belongs to the mite group 7 allergen family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1403_BACP2
Sequence: MAQVKRLLINYKTLEEFKQFKEYGIQELSMLEDLESNMIENDSNSPFYGIYFGDKLVARMSLYQVDGSTTTYFNHNHDYLELWKLEVLPGYQRKGYGEALVEFAKSFGLPIRTNPRVKSAGFWDKMGFESVKYDMERDKGENPLIWEPAHIQKNTGESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BPUM_1403.
Protein: PERM_ECOLI
Sequence: MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLVAIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLLTIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVLEMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPLATLIKAVIHAWPDGQIAQE
What are the official names of this protein?
Putative permease PerM.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: REP2_KLULC
Sequence: MPDNCHFVRSVDLLSVILLRLSTEVGLTLTTLPRHSKELILYHCTYEEHAVELSKPGLRKAGGKCSLFVDPEERENSPSPPIPPYQISEMPLHELLESGNAKLVPNPEFDLTDPDDFHKCFSVTYSALSLMVPYLPRAALKAARVFCKDHSILTTDMLDLNYLEELIEFSKETVNKIPARIPIEDMLLERGYVLPWVHGGTVKGGKLLTPND
What is the function of this protein?
Plasmid partition require REP1, REP2, and a cis-acting DNA sequence (known as STB).
What are the official names of this protein?
Trans-acting factor C, REP2.
Protein: BXB1_BOMMO
Sequence: MKTSVMFMLVIVISLMCSGEAQEVARTYCGRHLADTLADLCFGVEKRGGAQYAPYFWTRQYLGSRGKRGVVDECCFRPCTLDVLLSYCG
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin B-1, BBX-B1, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_BACCR
Sequence: MKMAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDTDYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFKTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: IL12A_SIGHI
Sequence: MCSSRCLLFLATLAFLIHLSLARATPVSTPAQCLAHSQNLLRTTNHMLEKAIQTLKHYPCTAEDIDHEDITEDKTSTLNACLPPELAKNESCWASGKTSSVTRGSCLPPQKTSSMMTLCLSSIYEDLKMYQTEFKAINAELLDHNRKQIILDENMLTAIDELMQALNLNGETRPQKPSLEEADPYKVKIKLCILLHAFSIRAITINRVMSYLNSA
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4761_BACC2
Sequence: MGRKWNNIKDKKASKDANTSRIYAKFGREIYVAAKQGEPDPESNQALRVVLERAKTYNVPRTIIDRAVEKAKGGSEENYDELRYEGFGPNGAMVIVDTLTNNVNRTAADVRAAFSKNSGNMGVNGSVAYMFDATAVIGLEGKTSDEVLEILMEADVDARDILEEEDSVIVYAEPDQFHSVQSALKGAGVEEFTVAELTMLAQSDVTLPEDAQVQFEKMVDALEDLEDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BCG9842_B4761.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAL1_ORYSJ
Sequence: MKPSDDKAQLSGLAQSEESSLDVDHQSFPCSPSIQPVASGCTHTENSAAYFLWPTSNLQHCAAEGRANYFGNLQKGLLPRHPGRLPKGQQANSLLDLMTIRAFHSKILRRFSLGTAVGFRIRKGDLTDIPAILVFVARKVHKKWLNPAQCLPAILEGPGGVWCDVDVVEFSYYGAPAQTPKEQMFSELVDKLCGSDECIGSGSQVASHETFGTLGAIVKRRTGNKQVGFLTNHHVAVDLDYPNQKMFHPLPPNLGPGVYLGAVERATSFITDDVWYGIYAGTNPETFVRADGAFIPFADDFDISTVTTVVRGVGDIGDVKVIDLQCPLNSLIGRQVCKVGRSSGHTTGTVMAYALEYNDEKGICFFTDILVVGENRQTFDLEGDSGSLIILTSQDGEKPRPIGIIWGGTANRGRLKLTSDHGPENWTSGVDLGRLLDRLELDIIITNESLQDAVQQQRFALVAAVTSAVGESSGVPVAIPEEKIEEIFEPLGIQIQQLPRHDVAASGTEGEEASNTVVNVEEHQFISNFVGMSPVRDDQDAPRSITNLNNPSEEELAMSLHLGDREPKRLRSDSGSSLDLEK
What is the function of this protein?
Involved in the regulation of lateral leaf growth (PubMed:18562767, PubMed:22179305, PubMed:23985993).  May be involved in the regulation of basipetal polar auxin transport (PAT) and vascular patterning in leaves (PubMed:18562767).  Controls photosynthesis rate by regulating carboxylation efficiency and consequently photosynthesis rate (PubMed:23985993).  Controls panicle and spikelet numbers, and grain yield (PubMed:23985993, PubMed:24297875, PubMed:24795339).
What are the official names of this protein?
Protein NARROW LEAF 1, Protein GREEN FOR PHOTOSYNTHESIS, Protein QUANTITATIVE TRAIT LOCUS FOR FLAG LEAF WIDTH 4, qFLW4, Protein SPIKELET NUMBER.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Expressed in discrete structures which appeared similar to nuclear protein bodies.
Protein: HEMH_CHESB
Sequence: MTLERTGRDEEKALTQPPSGHSSVQAGKVGVLLVNLGTPDGTDYWPMRRYLGEFLSDRRVIEWPRAVWYPILYGIILARRPKKSGALYAKIWNREQNESPLRTFTRAQGQKLATALADKENVIVDWAMRYGSPSIETVTKSLIERGCDRIVMFPLYPQYSATTTATVNDKFFEALIEMRHQPAVRTVPAYPEEPVYIDALVRSIERHLATLDFEPEVVVASYHGIPQSYARRGDPYYEQCLATTARVRERLGWDEKKLITTFQSRFGPEEWLQPYTDKTVEQLARDGVRSIAVINPGFVSDCLETLEEIAVEADRTFREAGGKNFTHIPCLNDSDEGMAVIESLIRREMSGWA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_THEVB
Sequence: METITYVFIFACIIALFFFAIFFREPPRITKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.  PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T, PSII-Tc.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MTK2_ORYSJ
Sequence: MAAAAAEQQQQGFRPLDEASLVAYIKATPALAARLGGRLDALTIKEVGDGNLNFVYIVLSDAGSLVIKQALPYIRLVGDSWPMSRERAYFEASALQKHRALCPDHVPEVYHFDRAMSLIGMRYIEPPHIILRKGLVAGVEYPLLAEHMADYMAKTLFFTSLLYNSTTDHKKGVAQYCDNVEMSRLTEQVVFSDPYRVAKYNRCTSPFLDNDAAAVREDAELKLEIAELKSMFIERAQAFLHGDLHTSSIMVTPDSTQVIDPEFAFYGPMGYDIGAFLGNLILAYFSQDGHADQANDRKAYKKWILKTIEDSWNFFHKKFVELWNKHKDGNGEAYLPPIYNSSELLSLVQKKYMTSLFHDSLGFGSAKMIRRIVGIAHVEDFESIEDASKRASCERRALNCAKAILKGRRQFESIEQVIVHVQSFDRD
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase 2, MTR kinase 2, OsMTK2.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: RS16_CHLPD
Sequence: MVKIRLKRTGRKKLPIYQIVAADARSPRDGKFLEVIGHYQPTAKPHAVTIKKDRVAYWMQTGAQPTDTVRSLIRSTGLLYEMRLKKMGRSEEEIVSEMEKWQARQTERRQKRLVVKSRRRQAKKEAEGKAAGAEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y254_STRP7
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SP70585_0254.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: CYB_CAPSI
Sequence: MTNIRKTHPLMKIVNNTFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHIGRGLYYGSYTFLETWNIGVLLLFTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALAMVHLLFLHETGSNNPTGIPSNTDKIPFHPYYTIKDILGATLLILALMLLVLFMPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALALSILILVLVPFLHTSKQRSMMFRPISQCMFWVLVADLLTLTWIGGQPVEHPYVIIGQLASIMYFLIILVIMPTASIIENNLLKWK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURA_HELPS
Sequence: MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGASLEWLDPNTLQISAKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKGITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAGTYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTKEYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVARLKEK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX20_HUMAN
Sequence: MASPEHPGSPGCMGPITQCTARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTRELQQYWQNQKCRWKHVKLLFEIASARIEERKVSKFVVYQIIVIQTGSFDNNKAVLERRYSDFAKLQKALLKTFREEIEDVEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHRDLDRPAEAFAAGERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLEESQLRRPTPRGITLKELTVREYLH
What is the function of this protein?
May play a role in cellular vesicle trafficking.  Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion.
What are the official names of this protein?
Sorting nexin-20, Selectin ligand-interactor cytoplasmic 1, SLIC-1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane. Cytoplasm. Nucleus.
Protein: S2551_HUMAN
Sequence: MMDSEAHEKRPPILTSSKQDISPHITNVGEMKHYLCGCCAAFNNVAITFPIQKVLFRQQLYGIKTRDAILQLRRDGFRNLYRGILPPLMQKTTTLALMFGLYEDLSCLLHKHVSAPEFATSGVAAVLAGTTEAIFTPLERVQTLLQDHKHHDKFTNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFGLRGPIKEHLPTATTHSAHLVNDFICGGLLGAMLGFLFFPINVVKTRIQSQIGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEFLLKVI
What is the function of this protein?
Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria (PubMed:32906142, PubMed:33262325).  Mitochondrial NAD(+) is required for glycolysis and mitochondrial respiration (PubMed:32906142, PubMed:33262325).  Compared to SLC25A52, SLC25A51-mediated transport is essential for the import of NAD(+) in mitochondria (PubMed:32906142).
What are the official names of this protein?
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51, Mitochondrial NAD(+) transporter SLC25A51, Mitochondrial carrier triple repeat protein 1, Solute carrier family 25 member 51.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: CYB_PERFS
Sequence: MTILRKSHPIMKMINHAFIDLPAPSNISGWWNFGSLLGVCLIIQISTGLFLSMHYTSDTMTAFSSVSHICRDVNYGWLIRYMHANGASLFFICLYFHIGRGIYYGSYLYKETWNIGIILLFLVMATAFMGYVLPWGQMSFWGATVITNLLSAVPYIGPDLVEWIWGGFSVDKATLSRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDADKIPFHPYYSYKDLLGALMLLAFYLTIVLFFPDCMGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALILSILVLALFPLLHTSSQRSLMFRPISQVLFWLLVSDLFILTWIGGQPVEPPFIIIGQLASILYFSIILVLFPIAGLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS4_RHIE6
Sequence: MILFPAIDLKGGQCVRLKLGDMQQATVYNTDPAAQAKSFEEQGFEWLHVVDLDGAFAGHSANGDAVEAILKATKNPVQLGGGIRTLDHIEAWLARGLRRVILGTVAVRNPDLVIEACRKFPGHVAVGIDAKGGKVAVEGWAEASELGVIELAQKFEGAGVSAIIYTDIDRDGILAGINWASTLALAGAVSIPVIASGGLASLDDVRRMLEPDARKLEGAISGRALYDGRIDPRQALALIKASRAKETA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_KLEP3
Sequence: MSTTKLTRREQREHAQRFIDTLAGTAFPNSRRIYVHGSQADIRVPMREIELSPTLVGGDKDNPRYEANEPIPVYDTSGPYGDPDIGIDVRQGLAKLRQPWIDARNDCAPLSERSSAYTKARLADDGLDELRFSGLLTPKRAVAGKCVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRQQHAGEGFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAENLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKITQEVRDYAAKQNIEAGMADMSHHFRARGGEIYLKQEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.