PharMolix/UniProtQA huggingface dataset:
Protein: PEPM_STRVT
Sequence: MNATERPGSDGTGSPESVGSRLKNLLHGPGTCQLMGVHDGLSARIAVAEGFEALWASGLCMSTARGVRDSDEASWTELLTLVGTMTEAAPGAPVLVDGDTGYGNFNTARPSPPAPSCLGAAGVCFEDKVFPKMNSFFGDGHQLAPIGEFSGKIKACKDTQRDPGFVVVARTEALISNLPMEEALTRAHAYVEAVADGLFIHSRMSTPQQIAEFMRQWDGSAPILIAPTTYHRPSLDDFAALGIAGCIWANHSMRAAFSAMRDVCQQIRADRGIFGVEERVAPLKEIFGLLDYESLEQDENRYTQAPDLAPVQG
What is the function of this protein?
Formation of a carbon-phosphorus bond by converting phosphoenolpyruvate (PEP) to phosphonopyruvate (P-Pyr).
What are the official names of this protein?
Phosphoenolpyruvate phosphomutase, PEP mutase, PEP phosphomutase, Phosphoenolpyruvate mutase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. PEP mutase family.
Protein: C87DR_SIRGR
Sequence: MWTVVLGLATLFVAYYIHWINKWRDSKFNGVLPPGTMGLPLIGETIQLSRPSDSLDVHPFIQKKVERYGPIFKTCLAGRPVVVSADAEFNNYIMLQEGRAVEMWYLDTLSKFFGLDTEWLKALGLIHKYIRSITLNHFGAEALRERFLPFIEASSMEALHSWSTQPSVEVKNASALMVFRTSVNKMFGEDAKKLSGNIPGKFTKLLGGFLSLPLNFPGTTYHKCLKDMKEIQKKLREVVDDRLANVGPDVEDFLGQALKDKESEKFISEEFIIQLLFSISFASFESISTTLTLILKLLDEHPEVVKELEAEHEAIRKARADPDGPITWEEYKSMTFTLQVINETLRLGSVTPALLRKTVKDLQVKGYIIPEGWTIMLVTASRHRDPKVYKDPHIFNPWRWKDLDSITIQKNFMPFGGGLRHCAGAEYSKVYLCTFLHILCTKYRWTKLGGGTIARAHILSFEDGLHVKFTPKE
What is the function of this protein?
Catalyzes the oxidation of cucurbitadienol at the C-11 position to produce 11-oxo cucurbitadienol, a possible biosynthetic intermediate from cucurbitadienol to mogrol.
What are the official names of this protein?
Cucurbitadienol 11-hydroxylase, Cytochrome P450 87D18.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RTPR_LEVBA
Sequence: MNTATQASVSLTPEFIAATEKEITPHWGELGWVTYKRTYARWLPEQQRNEEWPETVKRVVEGNINLDPRLQADTVTPEVLTELTTEAQNLFRLIYGLAATPSGRNLWISGTDYQHRNGDALNNCWFIAVRPQAYGDSHILPSYLTQDQVAVSMPFSFMFDQLMKGGGVGFSVTPNNVHQMPVVDQTVDLTIVIDPESASYADSVALGAVNRSEWMHDNSLADVRFYRLPDTREGWVLANANMMDAHFNSTNPEKKTKVVLDISDIRPKNAPIHGFGGTASGPMPLVEMLFDINQILNNAVGRQLTAVDCTDMGNMIGKTVVAGNVRRSAELALGGAEDDAFITMKQDKDQLYHHRWASNNSVAVDSDFTDYAPIADSIQHNGEPGIVNLGLSRNYGRLIDGRQEGIDEAVEGTNPCGEISLSNGEPCNLFEVFPSVAEEQGWQLEDAFGLGARYTKRVTFSHYDWEVSRKAIQKNRRIGVSMSGIQDWILKTFKQRVVTGFEAKHDAETGKTFMQPIYNQAAVNRFNALYQAVVKADQDYSDTLGCQPSIKHTTVKPSGTVAKLAGVSEGMHFHYARYLIQRIRFQDSDPLLPALKASGYKVEPDVYSQNTMCVEFPVKAAHADEPAFASAGEVSMAEQFATQAFLQTYWSDNAVSCTVTFQPEEGQDISDLLLQYRHTIKSTSLLPYSGADFKQAPKEPIDAATYDAKCQEITADVAEKFAAMTGNHDQKDIELVDQSDCESGACPIR
What are the official names of this protein?
Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, RTPR.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: CHIP_ARATH
Sequence: MVTGVASAMAERLKEDGNNCFKKERFGAAIDAYTEAIALSPNVPAYWTNRALCHMKRKDWTKVEEDCRKAIQLVHNSVKAHYMLGLALLQKKEFTNGVKELQRALDLGRCSNPTGYMVEEIWEELSKAKYMEWELVSAMRSWELNSLKETCEAALNQQRALDMSRTEESSDEAYTAHTERLKALERVFKKAAEEDKPTEVPDYLCCNITLEIFRDPVISPSGVTYERAAILEHLKKVGKFDPITREKIDPANLVPNLAIKEAVAAYLEKHVWAYKMGC
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity and may target misfolded substrates towards proteasomal degradation.  Regulates the activity of some serine/threonine-protein phosphatases by E3 ubiquitin-protein ligase activity.  Required for responses to biotic and abiotic stresses such as auxin, abscisic acid (ABA), low and high temperature and darkness, probably through the activation of serine/threonine-protein phosphatase and the subsequent modification of the plasma membrane composition.  Regulates the chloroplastic Clp proteolytic activity in response to stresses.  Ubiquitylates FtsH1, a component of the chloroplast FtsH protease, and affects protein degradation in chloroplasts.  Mediates plastid precursor degradation to prevent cytosolic precursor accumulation, together with the molecular chaperone HSC70-4.  Mediates ubiquitination of transit peptides and thereby led to their degradation through the ubiquitin-proteasome system.
What are the official names of this protein?
E3 ubiquitin-protein ligase CHIP, Carboxyl terminus of HSC70-interacting protein, AtCHIP, Plant U-box protein 61, RING-type E3 ubiquitin transferase CHIP, U-box domain-containing protein 61.
Protein: SIAA_NEIMB
Sequence: MKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTYKEVTRENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRLEALAGAAVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMGEKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNIISIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLGKFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL
What is the function of this protein?
Catalyzes the conversion of UDP-N-acetylglucosamine (UDP-GlcNAc) to UDP and N-acetyl-D-mannosamine (ManNAc).
What are the official names of this protein?
UDP-N-acetylglucosamine 2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
Protein: ILVC_CLOBA
Sequence: MTKMYYEKDTDLNLLKGKTIAVIGYGSQGHAHALNAKESGCNVIIGLYEGSKSWGKAEAQGFEVFSTAEAAKKADIIMILINDELQAAMYKKDIEPNLESGNMLMFAHGFNIHFDQITAPKDVDVTMIAPKGPGHTVRSEYQLGKGVPCLVAVHQDATGRALETALAYANAIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETLVEAGYDERNAYFECIHEMKLIVDLIYQSGFAGMRYSVSNTAEYGDYITGSKIITEETKKTMKKILKDIQDGTFAKDFLLDMSEAGGQAHFKAMRKLAAEHKSEAVGSEIRKLYCWNNEDKLINN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HEM3_MYXXD
Sequence: MMTHVRIATRQSPLALWQARHVGALLTSRHPGLEVTLVEMTTEGDRFLSAPLSAVGGKGLFVKEIEQALLDGRADIAVHSLKDMTSVFPEGLILAAVPEREDPRDVFCGLGGLTLDTLPQGARVGTSSLRRSCILRSRRPDVDIVSVRGNVQTRLARTREQGLAGALLAYAGLKRLGLEDVITQVLPPEVSLPAVGQGVLAIQCRTDDARVRALLVPLEHATTRIAVTAERALLAKLEGGCTVPLAGYATVSGDTVFLRGLVGRPDGTHVVRGEVRGPVSQAHALGESLADDLLSRGAADILRDFARRFEARES
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PC11X_HUMAN
Sequence: MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHPL
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.
What are the official names of this protein?
Protocadherin-11 X-linked, Protocadherin-11, Protocadherin on the X chromosome, PCDH-X, Protocadherin-S.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SKP1_HUMAN
Sequence: MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.  In the SCF complex, serves as an adapter that links the F-box protein to CUL1.  The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.  SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.  SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.  SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2 (PubMed:25704143).  SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.  SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1.  SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.  SCF(FBXW2) directs ubiquitination of GCM1.  SCF(FBXO32) directs ubiquitination of MYOD1.  SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5.  SCF(FBXO33) directs ubiquitination of YBX1.  SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53.  SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription.  SCF(CCNF) directs ubiquitination of CCP110.  SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2.  SCF(FBXO9) directs ubiquitination of TTI1 and TELO2.  SCF(FBXO10) directs ubiquitination of BCL2.
What are the official names of this protein?
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, p19A, Organ of Corti protein 2, OCP-2, Organ of Corti protein II, OCP-II, RNA polymerase II elongation factor-like protein, SIII, Transcription elongation factor B polypeptide 1-like, p19skp1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: RL24_RICRS
Sequence: MIKLKVKKGDEVVVITGKHKGKKGKILKVFPEDSKVIVSGVNVVKKHTKPNQMSEGGIITKELPIHISNIAHIDPKTGNPTKVAFKFLEDGSKVRVAKKSGEIIGKEGK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PETN_SOLBU
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: THD1_CICAR
Sequence: MLSTSTTNSSILPFRSRASSSTFIARPPANFNSIFTTSVRVFPISMSRYCVFPHTWERDHNVPGVPGVLRKVVPAAPIKNKPTCADSDELPEYLRDVLRSPVYDVVVESPVELTERLSDRLGVNFYVKREDRQRVFSFKLRGPYNMMSSLSHEEIDKGVITASAGNHAQGVPFPFPGRRLKCVAKIVMPTTTPNIKLDGVRALGADVVLWGHTFDEAKTHAVELCEKDGLRTIPPFEDPAVIKGQGTIGSEINRQIKRIDAVFVPVGGGGLIAGVAAFFKQIAPQTKIIVVEPYDAASMALSVHAEHRAKLSNVDTFADGATVAVIGEYTFARCQDVVDAMVLVANDGIGAAIKDVFDEGRNIVETSGAAGIAGMYCEMYRIKNDNMVGIVSGANMNFRKLHKVSELAVLGSGHEALLGTYMPGQKGCFKTMAGLVHGSLSFTEITYRFTSHRRSILVLMLKLEPWRYIEKMIEMMKYSGVTVLNISHNELAVIHGKHLVGGSAKVSDEVFVEFIIPEKADLKKFLEVLSPHWNLTLYRYRNQGDLKATILMVIASFLCEIVIRKNQIDDLGYPYEIDQYNDAFNLAVTE
What are the official names of this protein?
Threonine dehydratase biosynthetic, chloroplastic, Threonine deaminase, TD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: H2B_ACRFO
Sequence: MAPKVRAAKKGEKRVGKAKSGTAETAKRRRGKRKESYAIYIYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAVESSRLSLYNKKATISSREIQTAIRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PDXA_SHEFN
Sequence: MTKRIAITPGEPASIGPDLVIKLAQQAWPVELVVCADPNLLMTRAKMLGLPLQLRPYQPSQPPKPQTAGTLTIAPFTLAEEVECGVLNEANSAYVVETLRYAGEKNMSNEFDAVVTGPVHKGIINQAGIPFSGHTEFFALQANCADVVMMLAAPGLQVALMTTHIPLAYVAKAITRDRLHHIITILHRELVSKFGLGSPKIYVCGLNPHAGEDGHLGREEIDTIIPALNELREQGMDIVGPLPADTLFQPKYLEQADVVLAMYHDQGLPVLKSLGFGKSVNITLGLPYIRTSVDHGTALELAGSGKADCGSFTCALNKAIELASKSK
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIP12_MUSAC
Sequence: MEGKEEDVRLGANKFTERQPIGTAAQSQDKDYKEPPPAPLFEPGELSSWSFYRAGIAEFVATFLFLYITILTVMGVVKSSTKCSTVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALFYMVMQCLGAICGAGVVKGFQKGLYENNGGGANVVAPGYTKGDGLGAEIVGTFILVYTVFSATDAKRSARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKGHAWDDHWI
What is the function of this protein?
Water channel required to facilitate the transport of water across cell membrane; mercury-insensitive (By similarity).  Contributes to the tolerance to multiple abiotic stresses including salt (NaCl), cold and water deprivation, by modulating cytosolic K(+)/Na(+) ratio, maintaining osmotic balance, and reducing membrane injury (e. g.  oxidative injury) (PubMed:23745761).
What are the official names of this protein?
Aquaporin PIP1-2, Plasma membrane intrinsic protein 1-2, MusaPIP1-2, MusaPIP1;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAB_BEII9
Sequence: MSGFNDSPVPESAEKADGLLSQERGTQDPLVNTRKLFVKSYGCQMNVYDAERMADLLAPEGYAETSAPEDADLVILNTCHIREHAAEKVFSELGKLRLLKAEQQAAGRPVKIVVAGCVAQAEGEEILRRQKAVDLVVGPQSYHRLPDLLRRVAHTPGLVDTEFPAEDKFDHLVAPQPEKIAERGVGAFVTVQEGCDKFCSFCVVPYTRGAETSRPVEAILAEVETLIASGVREVTLIGQNVNAYHGFDAMTGAPASLASLMARVAAMPGLLRIRYTTSHPNDMGEDLIAAHRDIPALMPFLHLPVQSGSDKILAAMNRRHKAGDYLELIASIRAARPDIALSSDFIVGFPGETEADFEATLALIEQVGFASAFSFKYSQRPGTPGADRPDQIDEDVKAQRLARLQALLEEQRQAFNKAMIGRVLPVLFEKPGRHPGQIAGKTPYLQALYAEGDKALIGTVQPVEILEAGPNSFHGRLLARETGQESAQGQESAQGMERMEQNARAWEVPV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VINT_SSV1
Sequence: MTKDKTRYKYGDYILRERKGRYYVYKLEYENGEVKERYVGPLADVVESYLKMKLGVVGDTPLQADPPGFEPGTSGSGGGKEGTERRKIALVANLRQYATDGNIKAFYDYLMNERGISEKTAKDYINAISKPYKETRDAQKAYRLFARFLASRNIIHDEFADKILKAVKVKKANADIYIPTLEEIKRTLQLAKDYSENVYFIYRIALESGVRLSEILKVLKEPERDICGNDVCYYPLSWTRGYKGVFYVFHITPLKRVEVTKWAIADFERRHKDAIAIKYFRKFVASKMAELSVPLDIIDFIQGRKPTRVLTQHYVSLFGIAKEQYKKYAEWLKGV
What is the function of this protein?
This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome.  Essential for virus infection.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: QUEC_SHISS
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: GERPC_BACSU
Sequence: MYDQSVSSYLQNLNSFVQQQAIHIQQLERQLKEIQTEMNTMKQRPATTIERVEYKFDQLKIERLDGTLNIGLNPTDPNSVQNFDVSQSTPQIGMMQQEESAQLMQQIRQNVDMYLTEEIPDILEQLENQYDSRLDDTNRHHVIEDIRKQMDSRIHYYMSHIKKEENTPPAQYAEHIAEHVKRDVIRAVEHFLEHIPSEMKGDEQA
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPC.
Protein: TSPY1_RAT
Sequence: MENSEEESVGVAPQEFRELVLLESSLLEGEPSVQAPEQSPGAPAGDNQMVKPLVICGPVEDWVPLAEVLHHPDTCEEGDEATMAELKVTEVVDVKNEGEEVKDQKQEGEQDQQPELEKNPEQACDSKDQQGIQRLPLSGGGPAERRSKMEELELLQLELSFVNARCSGAFARIKAKVAKMRRPHFDRRKTIIQGIPGFWAKAMMNHPQMSSIISNQDEDLLSYMLSLEVEEYNPGLRMCRMMFFFSENPYFRNDIVTKDYQLSIIGYKESDSSTIEWIGQAEHGYANCMQDTTRLTFFNWLCAHKFPGSNRIAEIIMDDLWPNPLYYYPKEDHS
What is the function of this protein?
May be involved in sperm differentiation and proliferation.
What are the official names of this protein?
Testis-specific Y-encoded protein 1, rTSPY.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.
Protein: HSLV_RICCK
Sequence: MSDNLALHGTTILCLKKNEDIIIAADGQVSHGNTILKSSARKLRTIANNKIIAGFAGSTADGLALFEKLEAKIEKYSYNLLRSAVELAKDWRSDKYLRRLEAMMIVADRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSCENNLTAEEIALKSMNIAADLCVFSNRNIIMEKVV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_XYLF2
Sequence: MNQDHPECDSEELTQNSPETDPLKVEVETLRGEIASIKADVLRERAELENQRKRLIRDVEQARKFANEKLLGELLPVFDSLDAGLTASGSEPSPLRDGLELTYKQLLKVAIDNGLMLLDPVGQLFNPEHHQAISQTEVTDVEPGHVIQVFQKGYLLNERLLRPALVVVAKQD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP321_ARATH
Sequence: MVEKDIYMCAEIIIRPQAYNLRLLQKENLKKMSVCSSTPVPILSFTERAKSLTEIQQAHAFMLKTGLFHDTFSASKLVAFAATNPEPKTVSYAHSILNRIGSPNGFTHNSVIRAYANSSTPEVALTVFREMLLGPVFPDKYSFTFVLKACAAFCGFEEGRQIHGLFIKSGLVTDVFVENTLVNVYGRSGYFEIARKVLDRMPVRDAVSWNSLLSAYLEKGLVDEARALFDEMEERNVESWNFMISGYAAAGLVKEAKEVFDSMPVRDVVSWNAMVTAYAHVGCYNEVLEVFNKMLDDSTEKPDGFTLVSVLSACASLGSLSQGEWVHVYIDKHGIEIEGFLATALVDMYSKCGKIDKALEVFRATSKRDVSTWNSIISDLSVHGLGKDALEIFSEMVYEGFKPNGITFIGVLSACNHVGMLDQARKLFEMMSSVYRVEPTIEHYGCMVDLLGRMGKIEEAEELVNEIPADEASILLESLLGACKRFGQLEQAERIANRLLELNLRDSSGYAQMSNLYASDGRWEKVIDGRRNMRAERVNRSLDVA
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g18840.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: HSLO_BACLD
Sequence: MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGEDKLTVKIEGGGPIGAIVADGNAKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVKDLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVGVLVNPDNTILAAGGFILQLLPGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKERFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4HA2_MOUSE
Sequence: MKLQVLVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDDEDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-2, 4-PH alpha-2, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.