PharMolix/UniProtQA huggingface dataset:
Protein: RS12_ECO55
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: YNGD_CLOPF
Sequence: MENIINYIKWGIVSLGTLFTWIFGAWDIPLITLLVFIFLDYLTGVIKGCKSKELCSNIGLRGITKKGLILVVLLVAVMLDRLLDNGTWMFRTLIAYFYIMNEGISILENCAALGVPIPEKLKQALKQLNNKK
What are the official names of this protein?
Uncharacterized 14.9 kDa protein in nagH 3'region, ORFD.
What is the protein family that this protein belongs to?
Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUC_PHOLL
Sequence: MAKTLYQKLYDAHIVREVPNETPLLYIDRHLVHEVTSPQAFDGLRTKGRPVHQPGKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCAEFGITLYDLNHPYQGIVHVIGPEQGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLASQTLKQARAKTMKIEVMGDVGDAITAKDIVLAIIGKTGSAGGTGYVVEFCGKAIEALSMEGRMTLCNMAIEMGAKAGLVAPDETTFTYMKGRQFSPKGELWEQAVAYWKTLKSDPDAQYDTIVTINAEEISPQVTWGTNPGQVIAIDQTIPAPESFSDPVERASAEKALAYMDLKPGIKLTDVKIDKVFIGSCTNSRIEDLRAAAAIAQGHKVAPGVQAIVVPGSGPVQAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLQPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAINGHFIDIRHPAQKS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SUCC_RICRS
Sequence: MNIHEYQAKEILRKYGVPTSTGLVVTKTEKINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNRLYIESGCEILKEYYFSIVFDRSASCITFIASTEGGVDIEEVAEKTPEKIIKFSVDPATGLQDFHMRGIAYELGFKDNQAKQMKEIVKSVYNAFIETDAAQIEINPLIVNSDGNLLALDAKITFDDNGLLRHPNITAMRDHDEEDPLETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGASPANFLDVGGGADRERVKEALKIILSDKAVQGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGKEILSNSGLEIIPAHDLADAANKIVEAIR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YDJ1_CAEEL
Sequence: MSEDNLQMVVVQAQNCGVLHVYVQGNLEERGGKTIILTVHDIGTNHKSFVRFVNHPSMATVKEKAIFLHVCVPGQEDNSADFFGDFPTLDGIGDDLSAVLDKFEVKSAIAFGEGVGANIICRFAMGHPNRIMGIVLVHCTSTTAGIIEYCKEKVMNMRLENSIMSDGAWDYLLAHKFGGESKSRQEYLEELKATLNPKNLSKYLVAFTKRTDLSSTIGTKLETVDALLVTGSKASHLHTVYTTHKSMNKKKTTLLVVDNVADVMQEAPDKLARSLILLCKGCGVLSGVAIPGMERQRTLSSSMEEADRPRRMSVTQPHLPPVPSA
What are the official names of this protein?
Uncharacterized protein ZK1073.1.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
Protein: FENR1_LISMO
Sequence: MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKQQAETFHPTIVCSERVVDVTKLADGTFQLTSHNGSIHFSKTIVIATGSGTFEVNKLEALHAEDFPFAIHYDVKNIEQFRDKVVVVSGGGNSAIDWAQTLEPIAKKVHLIYRGEDFKAHEESVRELKNSRVEIHIHHEISELIGTNNQLTEITVCCNQTQTTKTIETEALFINHGVKVDLGTMAEWGFKQADFGIVVDDEMKTTVPGIFACGDSATYPRKIRIIAAGLHEGPIAINSAKKYLEPTAADEAMISTHHESFIG
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: V55_BPT3
Sequence: MAITKKFKVSFDVTLKLDSETEELMREKILDLAHRAGAGEEITPMDRELLVQALTRGPDGAAAFAVRQGIRNAVKEMFEETSDKSLLKLSPATVREVF
What are the official names of this protein?
Gene 5.5 protein.
Protein: RN181_BOVIN
Sequence: MASYFDEHDCEPLDRERDPRTNMLLELARSLFNRMDFEDLGLVVDWDHHLPPPAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTNSCPLCRHELPTDDDTYEEHKRDKARKQQQKHRLENLHGAMYT
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Catalyzes monoubiquitination of 26S proteasome subunit PSMC2/RPT1.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF181, RING finger protein 181.
What is the protein family that this protein belongs to?
Belongs to the RNF181 family.
Protein: CWP21_ARATH
Sequence: KDLXHRDDKT
What are the official names of this protein?
36 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CND3_HUMAN
Sequence: MGAERRLLSIKEAFRLAQQPHQNQAKLVVALSRTYRTMDDKTVFHEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFHQSDMEDDEEEEDGGLLNYLFTFLLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPKDDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMSIAQRVMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSEVAVSVLNALFSITPLSELVGLCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIRAPIVTVGVNNDPADVRKKELKMAEIKVKLIEAKEALENCITLQDFNRASELKEEIKALEDARINLLKETEQLEIKEVHIEKNDAETLQKCLILCYELLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHFVLLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTEINSDDEQESKEVEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLILLWYNPVTEEDVQLRHCLGVFFPVFAYASRTNQECFEEAFLPTLQTLANAPASSPLAEIDITNVAELLVDLTRPSGLNPQAKTSQDYQALTVHDNLAMKICNEILTSPCSPEIRVYTKALSSLELSSHLAKDLLVLLNEILEQVKDRTCLRALEKIKIQLEKGNKEFGDQAEAAQDATLTTTTFQNEDEKNKEVYMTPLRGVKATQASKSTQLKTNRGQRKVTVSARTNRRCQTAEADSESDHEVPEPESEMKMRLPRRAKTAALEKSKLNLAQFLNEDLS
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
What are the official names of this protein?
Condensin complex subunit 3, Chromosome-associated protein G, Condensin subunit CAP-G, hCAP-G, Melanoma antigen NY-MEL-3, Non-SMC condensin I complex subunit G, XCAP-G homolog.
What is the protein family that this protein belongs to?
Belongs to the CND3 (condensin subunit 3) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: NADD_STAAT
Sequence: MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHHDFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SNAT_BOVIN
Sequence: MSTPSIHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPKDAAGVFEIEREAFISVSGNCPLNLDEVRHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLTLHRPGGRTAHLHALAVHHSFRQQGKGSVLLWRYLQHAGGQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAVVVGSLTFTEMHCSLRGHAALRRNSDR
What is the function of this protein?
Controls the night/day rhythm of melatonin production in the pineal gland.  Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
What are the official names of this protein?
Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. AANAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAMA_BACC4
Sequence: MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEATAVLAEGRISNKDLGIWDDNLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPSAIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDVIELHGAHGYLINEFLSPLTNKRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKEQGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNEADLIFIGRELLRNPYFPRIAANELGFELQEPYQYKRAPGKIHTNK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: RPOC_MESH2
Sequence: MNTKVSRQYAKISENSIQKISLALATPEDVLEWSRGEVHRPETINYKTFKPERGGLFDELIFGPLVDYKCSVCGRKYRKSNENQLCIATKECKIRGSRILSKMARRYSMGHIALNAPILHFWFFKIDHSIIAKLLGLKVFEGNSKVPTTITKTAIENLIYYKSHIVLETGGLKSLEQNKIIDISEAGLIYKNALIEIIEFYPPGSEEHNALAESISELADVTSSKIGREYGVDYYELNEIIEEFSSARIATGALAIEYLLDKIDLRAEKAAVEAELAGVQKQIYKNKKIILKNQKRDKLYKRLQVINAFINSGQDPKMMIIRNLPVIPADLRPLVQLDGSRHSTSDCNELYRRIIIRNNRLKRWKAAHAPVIIIQNEMRMLQEAVDALIDNQKKSTNQVTTKEGRPLKSISDALTGKKGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQAGLPRKMAAVLFEPWIIRNLIQEKKVGSIKMARKMIEEENPIIWPHVAKVIQNKPIILNRAPTLHRLSIQAFEPVLVRAKAIQLHPLVTAGFNADFDGDQMAVHIPISPEAIRETQELMFADKNILGPKDGEPIVNPSQDMVLGLYYLSQEKAGAKGEGSFFSTYEAMLKAYEFRSVELHARVVLPFEQVKPFIAKTMRGHLISTVGKFILNNIFPANFPFIFDDNVDELELNYPSQIKKYVLPYGTNFREYIQNLKVNEPLNKKAIAKIVRQIFDTYDGLLAKEDIATVIDQLDFGNYQNRVLLYEKLRDYKKQKLPVPHLSKLSEFTIFEYSQLYKQLQQNGPVESYRVLEDHEKAELLEKIWFKYNNMVCSILDKIKDLGFHYSTLSGTSIAISDIKMAPKKHEFIKDGENYINKLNTFYAKGLITDDERYVLAIAKWTQIKNDIQEDLNQSIKDDNQNSLVMMMKSGARGNISNFVQLAGMRGLMANNVKALKVDAENERVVRSIVEVPVKSSFLEGLTSFEFYSSTHGARKGLTDTALNTAKSGYLTRRLVDVAQNIVVVAEDCFSDFGFVVKDIIDTKTNTIIVPLLERIEGRFLNKDVYDSRGIKLASAGSMVDLQTAKKIVAAGIKKVEIRSILSCHIKNSVCKKCYGKDLATNRLVSIGEAVGIIAAQSIGEPGTQLTMRTFHTGGVANVEDITGGFTRLIELIDSHEHPWGKPAKISPYYGIITKISDLAEKNAANKGFLITIEYKTSKNEKAEHIIRIEQSQKLRVKVGDKVIPGQKLVEGPIILKELLAVSDARTLQNYLLKEIQRIYRMQGISISDKYIEIIIRQMLSKVQIIENGDSNFFIGSIVDISDYQEVNGQLISQNKNPAFGNVIVKGAKQIPLLSNSFLAAASYQETSKILVHSVISSQIDKLEGLKENIIVGHKIPAGTNSNYEPKSKFDIRNPLSFFMKNNR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SEC9_CANGA
Sequence: MGIKKFFKIKPPKEDTVEQNRENLMDIGIATKSTTKKPQSKFAAYGQFAKDRATSKIYAPPGYEDFARPPEELEKKEGEEDDLNKSELDEKETKKDKKKKKKKHQQEDEPAAVQDPYARTEKSYRYNPDPYGAGAAGEKAFSSSGVYNEFNNYENGPSYGNEYGRRDRSEDLNAYNGTPGQPMKPVNRATPVLDRRDSAREDPAYGYNNQNRSNPYAGAGVGALAGGAAGGAVGAMGSVVSGSNPYGGASYGSGYGSSATTSAPVSKPISRTNTSASNPYGNASYGSTPGVNDRPAGSNPYAAISGDSYLNGTRSGNISRSGTNPYLRRNASNSVPPQAGYITPDSNNVALAEEENQQNQDELDLNDAPEDANEFVFEDKYMGRESKYAENSAALDELDLNATINDRGEDLNATGYGNMYEQQQQPQWQREEEEYGYGTQDDMNRGYKTFDEIQREEEERQKEEEDQAVDEIKEQIRFTKQSSVASTRNTLKMAQEAEMAGMNTLGMLGHQSEKLNNVERNLDLIKIQNTAADEKVAELKKLNRNILAVHVSNPFNSKRRRREREDMIKGRKMEDKMRAEHMSQELHQSTQRIEGALGGGNETSAVREKYQREKVLAAAKKYQFENDEEDDEMEVEIDRNLDKIQQISGRLKKLALATGEELDSQQRRIRDIEENTDEMDIKIHMNTTRLADIR
What are the official names of this protein?
Protein transport protein SEC9.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
Protein: TEG7_ELHVK
Sequence: MGAICGKCLRPYMADTQYETLQNEMDIQDLQTVMSYNLGLSSGDIAQLIDNEENKIKLMDILPTYMAYKTKLMRCEEAKDTCAEHLKDIVETERHKLQFIIKSLEIIMFKIAMGNLQVSDTQIEALAMKYATDQTTLSDLEKSLRVINEDRKCSFTLMKTSGDAMVEKNTDDEEILSGIECGTPQRCNVQQTSSRRHSHRASVDINQVIVVSDSIKEGHVSRETNISNEDCVNNTLMGSNGINLGGGKVLSSSKIVASSAISNTTINKQVTFKPDPADKEITLPDVPATDPAVLDVGEIGAAAGGAKQKVPRRERSLVASC
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: ARGC_GLOC7
Sequence: MGDTEQIPVGIIGASGYGGVQLVRLLIEHPNVEIVYLGGDSSAGKPYSDIYPHLFHCVNQPVEAIDIDEIASRCQVVFLGLPNGIACDLAPKLLEKGCKVLDLSADYRFRNLETYSTWYKKDRTDQAIAVRSVYGLPELYQQQIKESQLIGCPGCYPTASLLALAPLLKQGLIVPETAIIDAKSGTSGAGRQAKINALLAEADGSLGAYGVAKHRHTPEIEEVCSDLAGHEVTVQFTPHLIPMIRGILATVYATLRDPGLVREDLITIYNAFYRSSPFVKILPNGIYPQTKWACGTNLCYLGIEVDPRTDRVIVMSAIDNLIKGQAGQAVQCLNLMMGWEETLGLPQLCFYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDB_METKA
Sequence: MTSLADLPVDVSPRHEGERIRSGDMYVELAGPKSFGAELFKVVDPDEIEPDKVEVIGPDIDEMEEGGRYPFAIYVKAAGEELEEDVEGVLERRIHEFCNYVEGFMHLNQRDQIWCRVSKNVTEKGFRLEHLGIALRELYKEEFGNVIDSVEVTIMTDEEKVEEFLEYARRVYKKRDERAKGLSEEDVNEFYVCLMCQSFAPTHVCVITPDRPSLCGSITWHDAKAAYKIDPEGPIFPIEKGECLDPEAGEYEGVNEAVKEHSQGTVERVYLHSCLEYPHTSCGCFQAVVFYIPEVDGFGIVDREYPGETPIGLPFSTMAGEASGGEQQPGFVGVSYGYMESDKFLQYDGGWERVVWMPKALKERMKHAIPDELYDKIATEEDATTVEELREFLEKVEHPVVERWAEEEEEEEEKAPEEEAPAEEPTMEVKELPIAPGGGLNVKIVLKNAKIYAEKVIIKRADREDKS
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA.  The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit beta, ACDS complex subunit beta, ACDS complex acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CdhC family.
Protein: RISB2_BRUA2
Sequence: MNQSCPNKTSFKIAFIQARWHADIVDEARKSFVAELAAKTGGSVEVEIFDVPGAYEIPLHAKTLARTGRYAAIVGAAFVIDGGIYRHDFVATAVINGMMQVQLETEVPVLSVVLTPHHFHESKEHHDFFHAHFKVKGVEAAHAALQIVSERSRIAALV
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate (PubMed:10482294, PubMed:16165152, PubMed:20195542).  This is the penultimate step in the biosynthesis of riboflavin.  The isozyme RibH2 but not RibH1 is essential for Brucella intracellular survival and replication inside macrophages or in mice (PubMed:20195542).  Displays low catalytic activity in comparison with the isozyme RibH1 (PubMed:16165152).  Is a highly immunogenic protein (PubMed:14500496).  Activates dendritic cells (DCs) in vitro, increasing the levels of costimulatory molecules and the secretion of pro-inflammatory cytokines, and recruits DCs, B cells and CD8+ T cells in vivo, both effects in a TLR4-dependent manner (PubMed:16455994).  Induces the cross presentation of covalently attached peptides and generates a strong and long-lasting humoral immune response without adjuvants; TLR4 signaling is necessary for the induction of the cytotoxic response but not for antigen cross presentation (PubMed:23029192).  Elicits a TLR4-mediated protective response against B16 melanoma in mice, slowing tumor growth and prolonging mice survival (PubMed:25973756).
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2, BLS, Type II lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UN50B_XENLA
Sequence: MLPTTSVSPRSPDNGILSPRDATRHTAGAKRYKYLRRLFHFKQMDFEFALWQMLYLFTSPQKVYRNFHYRKQTKDQWARDDPAFLVLLGIWLCVSTVGFGFVLDMSFFETFTLLLWVVFIDCVGVGLLIATSMWFVSNKYMVNRQGKDYDVEWGYTFDVHLNAFYPLLVILHFIQLFFINHVILTGWFIGCFVGNTLWLIAIGYYIYITFLGYSALPFLKNTVVLLYPFAALALLYILSLALGWNFTAKLCLFYKYRVR
What is the function of this protein?
Involved in the cell surface expression of neuronal nicotinic receptors (By similarity).  Binds RNA (By similarity).
What are the official names of this protein?
Protein unc-50 homolog B.
What is the protein family that this protein belongs to?
Belongs to the unc-50 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y382_STRP3
Sequence: MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYSLYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLFKIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKANDTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVRNDLEYSIRINFPLISKFFNNDIESQLYVDKHVEKIKKYIEQKYKNISFSIDYHYYLTTTGSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFIPKTNVYDG
What are the official names of this protein?
Uncharacterized protein SpyM3_0382.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthetase 2 family.
Protein: A85C_MYCLE
Sequence: MKFLQQMRKLFGLAAKFPARLTIAVIGTALLAGLVGVVGDTAIAVAFSKPGLPVEYLQVPSPSMGHDIKIQFQGGGQHAVYLLDGLRAQEDYNGWDINTPAFEEYYHSGLSVIMPVGGQSSFYSNWYQPSQGNGQHYTYKWETFLTQEMPSWLQANKNVLPTGNAAVGLSMSGSSALILASYYPQQFPYAASLSGFLNPSEGWWPTMIGLAMNDSGGYNANSMWGPSTDPAWKRNDPMVQIPRLVANNTRIWVYCGNGAPNELGGDNIPAKFLESLTLSTNEIFQNTYAASGGRNGVFNFPPNGTHSWPYWNQQLVAMKPDIQQILNGSNNNA
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85C, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex C, 85C, Ag85C, Fibronectin-binding protein C, Fbps C.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: CARA_STAS1
Sequence: MLKKRYLVLEDGSYYEGYPIGSDQLTLGEIVFNTAMTGYQETISDPSYTGQIITFTYPLIGNYGINRDDFEALVPTLNGVVVKEASRQPSNFRKQKTFHEVLQEYDIPGISGVDTRSITRKIRNNGVLKAGFTDEKSEIDSMIAKLQSVELPRNEVTTVSTKSPYVSTGYGLSVVLVDFGKKQNIVRELNARGCNVTVVPYDTSAEAIIRMSPDGVMLSNGPGDPEEVHVAVEMIKGILGKIPFFGICLGHQLFALSQGATSFKMKFGHRGANHPVKDLKTGKIALTSQNHGYAIDKASLKNTDLEVTHIAINDDTVEGLRHKSLPAFSVQYHPEACPGPSDSNYLFDEFIDMINEYKTKELTNNA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: PRMA_CAMJ8
Sequence: MQKKYYELFFIVEERYKNLFLDFAFDLGIEAIEEKDNGVYIRSHESLEELSWALEIFAQKLTTTFNLNHKIISNLSLVEKENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNFINIKINPALAFGSGHHESTYSCVKFLQKFSKSKLRALDLGCGSGILGIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILILSGILDKYSTRIKEKFQDLELIDEMQINEWCSFVYKNNKKG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_COXBN
Sequence: MSTLRVLHEKSELGKTTVYPKEYAPHLLLPIPRDLNRKTLNVNVSEPPPFYGYDLWNAYELSWLNEKGKPFAARGEFIIPATSSHLIESKSFKLYLNSFNNERFADAAAVSQTMKRDLSKRVNESVTVNFILHETEIPVAYSPKGSLLDVLDIAIDTYSPDPNLLSTSQETVTETLYSHLLKSNCPVTGQPDWGSIEIHYTGPKIDHAQLLKYIISYRNHEEFHEACVERFFMDILRHCRPQELTVQARYTRRGGLDINPYRSTNPTFSVQNHRSFRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T120B_XENTR
Sequence: MSLQKCQEEWGELEKEFQQLQETHKVYKQKLEELNGLQNLCSSYINKHKRRLTELKGNLHGYKHTSNVEEKELVQQINSTIKERHNAFFDMEAYLPKKNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAITCRFVLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPDGLMYQIFRNQFLAFSIYQSCVQFLQYYYQSGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLYNAITLFGLSRHEECKEWQVFVLALTFLLLFLGNFLTTLKVVHTKFQKNKLKKP
What is the function of this protein?
Necessary for efficient adipogenesis.  Does not show ion channel activity.
What are the official names of this protein?
Transmembrane protein 120B.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: CINA_LACP3
Sequence: MQAEIIAVGTEILMGQITNTNGAYMAKQLTALGIDSYHQQVVGDNGPRLEEAIKLAESRSNLVILIGGLGPTPDDLTKQTLAAHLNRKLVEDPDAMAKLQARVKQQQRPMTPNNQLQAMYPEGADILVNRVGLAVGAWIVNGQHTYVLLPGPPKEFVPMVDHELLPRLAKWSGHAEVMVSRVLRFFGIGESQLVTDLDDLIANQTDPTIATYIKDHEVTVRVTASGATEKDADAKLEPMVGAIMDRDGQYFYGYGDDNSLAKELVKTLAANDMQITAAESLTAGAFQAALGDVPGVSTYFKGGFVTYSLATKAAFLAIDARELAAHGVVSAFTAKAMAEHARRKAAADISVSFTGVAGPDTLEGQPAGTVWIGLARRGQLPEAHVYHFPGGRNDVRQRAVMTGMMLALRALQA
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.