PharMolix/UniProtQA huggingface dataset:
Protein: GATC_KINRD
Sequence: MSAISRSEVEHLARLARIDMTDEELDRMAGQLDAVLDAVAQVASVVTDDVPATSHPVPLTNVTRPDVVRPGLTAEEALAGAPASEDGRFRVPQILGEEA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MNMG_LACP3
Sequence: MPDVKKFEAGTYDVIVVGAGHAGCEAALAAARMGQKTLLLTISLEMLAFMPCNPSLGGPAKGIVVREIDALGGEMGKNIDRTYIQMRMLNTGKGPAVRALRAQADKAAYHRSMKHVIENTPNLDLRQGLATEVLVENGQAVGIVAATGAMYRAKSVVLTAGTSSRGKIIIGELMYSSGPNNSLPSIKLSENLEQLGFKLRRFKTGTPPRVNGNTIDFDKTEEQPGDKTPNHFSFTTPDSVYLKDQLSCWMTYTNATTHQIIRDNLDRAPMFSGVIKGVGPRYCPSIEDKIVRFADKPRHQLFLEPEGRDTSEYYVGDFSTSMPEEIQLKMLHSVAGLEHAELMRAGYAIEYDVIEPWQLKATLETKVVDNLFTAGQMNGTSGYEEAAGQGIMAGINAALRAQGKGPFTLKRSDAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLKPMGHELGLISDERYAEFLAKRQAIETELNRLNTTRLKPKDVNPWLEAHHYAPLKDGVLASDFLKRPEIDYQTMAQFLPDNPTLDHRVIEQVEIQIKYAGYIAKEEASVAKLKRLEGKKIPLRINYAAINGLATEARQKLVKIQPETIAQASRISGVNPADVAILSVYIEQGRISKVAQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HELI_VZVO
Sequence: MKRSISVDSSSPKNVFNPETPNGFDDSVYLNFTSMHSIQPILSRIRELAAITIPKERVPRLCWFKQLLELQAPPEMQRNELPFSVYLISGNAGSGKSTCIQTLNEAIDCIITGSTRVAAQNVHAKLSTAYASRPINTIFHEFGFRGNHIQAQLGRYAYNWTTTPPSIEDLQKRDIVYYWEVLIDITKRVFQMGDDGRGGTSTFKTLWAIERLLNKPTGSMSGTAFIACGSLPAFTRSNVIVIDEAGLLGRHILTAVVYCWWLLNAIYQSPQYINGRKPVIVCVGSPTQTDSLESHFQHDMQRSHVTPSENILTYIICNQTLRQYTNISHNWAIFINNKRCQEDDFGNLLKTLEYGLPITEAHARLVDTFVVPASYINNPANLPGWTRLYSSHKEVSAYMSKLHAHLKLSKNDHFSVFALPTYTFIRLTAFDEYRKLTGQPGLSVEHWIRANSGRLHNYSQSRDHDMGTVKYETHSNRDLIVARTDITYVLNTLVVVTTRLRKLVIGFSGTFQSFAKVLRDDSFVKARGETSIEYAYRFLSNLIFGGLINFYNFLLNKNLHPDKVSLAYKRLAALTLELLSGTNKTPLHEAAVNGAGAGIDCDGAATSADKAFCFTKAPESKVTASIPEDPDDVIFTALNDEVIDLVYCQYEFSYPKSSNEVHAQFLLMKAIYDGRYAILAELFESSFTTAPFSAYVDNVNFNGSELLIGNVRGGLLSLALQTDTYTLLGYTFAPVPVFVEELTRKKLYRETTEMLYALHVPLMVLQDQHGFVSIVNANVCEFTESIEDAELAMATTVDYGLSSKLAMTIARSQGLSLEKVAICFTADKLRLNSVYVAMSRTVSSRFLKMNLNPLRERYEKSAEISDHILAALRDPNVHVVY
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs.  Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
What are the official names of this protein?
DNA replication helicase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae helicase family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CRP2_GADMO
Sequence: GRSLVFPEETANSFVELFPAKELSL
What is the function of this protein?
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.
What are the official names of this protein?
C-reactive protein P2 subunit 4, C-reactive protein PII subunit 4.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAB_PSEPK
Sequence: MSRPLTGALAHGFLGKSPIWYKVVICLFLVLNPLLLVTIGPVATGWALVLEFIFTLAMALKCYPLMPGGLLLIEALLLQMTTPQALYEELQHNFPVILLLMFMVAGIHFMKELLLFLFSRILLGVRSKAILALLFCVLSAFLSAFLDALTVTAVIISAAVGFYAVYHRVASGANPREDSALESDQQVAHLHREDLDQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFVDFFLKVAPVSLPVLGAGLVTCVLLEKVRLFGYGTLMPEPVRRVLTAYAAEDDAARTQAQRIALWVQGLAALILIICLGLHVAEVGLIGLMVIVLITAFTGITDEHRLGRAFQDAMPFTSLLVVFFAVVAVIHQQQLFSPLINWVLALPAEQQPGMLYLANGLLSAISDNVFVATIYITEVKQAFLDGSMSREHFETLAVAINTGTNLPSVATPNGQAAFLFLLTSAIAPLIRLSYGRMVWMALPYTVVMGGLGWWAVTYWL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TGT_BACCQ
Sequence: MTAIRYEFIKTCKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEELKAMDSGIILSNTYHLWLRPGHEIVREAGGLHKFMNWDRAILTDSGGFQVFSLSDFRRIEEEGVHFRNHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLKAHERPQDQGLFGIVQGGEFEELRRQSAKDLVSMDFPGYAVGGLSVGEPKDIMNRVLEFTTPLLPDNKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFARDFGPLDPNCDCYTCKNYSRAYIRHLMKCDETFGIRLTSYHNLHFLLNLMEQVRQAIREDRLGDFREEFFEQYGFNKPNAKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: FABH_STRS7
Sequence: MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRHISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATNAFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDGAGGVLLEASEQQHFLAEALHTDGARGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIFDFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMHYGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCM1_MESMA
Sequence: MNYLVMISFALLLMTGVESVRDAYIAKPHNCVYECARNEYCNDLCTKNGAKSGYCQWVGKYGNGCWCIELPDNVPIRVPGKCHR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels thereby blocking neuronal transmission.  This toxin is active against both mammals and insects, and is classified as an alpha-like toxin.  It is active on Nav1. 2/SCN2A (EC(50)=139-252 nM), Nav1. 3/SCN3A (EC(50)=565 nM), Nav1. 4/SCN4A and Nav1. 5/SCN5A (EC(50)=195-500 nM), Nav1. 6/SCN8A (EC(50)=214 nM), and drosophila DmNav1 (EC(50)=30 nM) (PubMed:11322948, PubMed:12705833, PubMed:15677695, PubMed:19162162, PubMed:20678086).  In mNav1. 6/SCN8A, the toxin induces a large increase in both transient and persistent currents, which correlates with a prominent reduction in the fast component of inactivating current (PubMed:20678086).  In rNav1. 2/SCN2A and rNav1. 3/SCN3A, toxin-increased currents is much smaller (PubMed:19162162, PubMed:20678086).  Moreover, the toxin only accelerates the slow inactivation development and delay recovery of mNav1. 6/SCN8A through binding to the channel in the open state (PubMed:20678086).  Is 6-fold more toxic than BmK-M2.  In vivo, intrahippocampal injection into rat induces epileptiform responses (PubMed:16229835).  In addition, intraplantar injection into rat induces spontaneous nociception and hyperalgesia (PubMed:14554105).
What are the official names of this protein?
Alpha-like toxin BmK M1, BmK-M1, BmKM1, BmK-I, BmK I, BmKI, BmK1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLAT3_HUMAN
Sequence: MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
What is the function of this protein?
(Microbial infection) Acts as a host factor for picornaviruses: required during early infection to promote viral genome release into the cytoplasm (PubMed:28077878).  May act as a cellular sensor of membrane damage at sites of virus entry, which relocalizes to sites of membrane rupture upon virus unfection (PubMed:28077878).  Facilitates safe passage of the RNA away from LGALS8, enabling viral genome translation by host ribosome (PubMed:28077878).  May also be involved in initiating pore formation, increasing pore size or in maintaining pores for genome delivery (PubMed:28077878).  The lipid-modifying enzyme activity is required for this process (PubMed:28077878).
What are the official names of this protein?
Phospholipase A and acyltransferase 3, Adipose-specific phospholipase A2, AdPLA, Group XVI phospholipase A1/A2, H-rev 107 protein homolog, H-REV107, HREV107-1, HRAS-like suppressor 1, HRAS-like suppressor 3, HRSL3, HREV107-3, Renal carcinoma antigen NY-REN-65.
What is the protein family that this protein belongs to?
Belongs to the H-rev107 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Peroxisome membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Nucleus envelope. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=During eye lens differentiation, recruited from the cytosol to various organelles, including mitochondria, endoplasmic reticulum, nuclear envelope and lysosomes, immediately before organelle degradation. This translocation is triggered by organelle membrane damage and requires the C-terminal transmembrane domain.
Protein: MGSA_COXBR
Sequence: MTVKKIALVAHDRMKKELIEWIKKHQNLLKHHELYATGSTGQAIEKTLNVTVTKMESGPLGGDLQLGVKIVNKEIDILIFFWDPLEAQPHDPDVRALLRIAVVWNLPVACNASTADYLLTSPLFDSDYHPETPDYEAYRNRII
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RS4_ACIB3
Sequence: MARYIGPKCKLSRREGTDLQLKSGVKPFDVKTKKANKAPGQHGQARGGKQSEYSLQLREKQKVRRIYGVLERQFSNYYKEAARVKGATGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHRSITLNGRRVNIASIQVKAGDVIAVHEGAKQQLRIKNAIELAAQRGIPAWIEVDHSKLEGTFKAAPDRSDLPAEINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GABD_DEIRA
Sequence: MTATPQASARPERPFATVNPYTGETVKTFPFLESAEIPALIERADQAYREWGQRPVTERAAIMRRAAELMLERTDELASLITLEMGKLLREAKGEVALAASILNYYGEQGPSFLEPKTIPVPQGEAAVLHAPLGVLLGIEPWNYPLYQVVRFAAPNLVVGNTVLLKHSELCPQSALALEQLFHDAGVPQGAYTNLFLRIADIEQVIAHPAVQGVSLTGSERAGASVAELAGRHLKKCVLELGGSDPFIVLDAEDLDTTVKAAATGRLSNTGQACIAAKRLMVVDDLYDEFVSRLGQTFSAFVPGDPADPSTRLGPLSSEQAARDLQAQVQDAIDKGATVVAGGQRPEHPGAFVQPTVLTDVTPDMRAYHEELFGPVAVVYRVRDEDEAVALANASTYGLGGAVFSSDLDRAQRVAERLDTGMVWINHPTSSAADLPFGGVKRSGFGRELSSMGMLEFTNQKLVRAFPTKQKPAQVAG
What is the function of this protein?
Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)], SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: URE1_PSEPF
Sequence: MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLLAAEVVDTVITNALIIDHWGIVKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTCTSGPWHLARMLQAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAKRYIAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYGGSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTYQVKADGVLLWCEPAETLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHA4_RAT
Sequence: MEQGRPRSSLSLTSSASTVSSLSSLSAKKPTRVVHKVHAFGKRNNALRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYSVRPDGPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGKASRAEGEDCGLPRSPARPRPGEGPGGPGGPPEVNRREEGRTSESPEVAPLSRGPGRHEMHAPGSSADLQPDTWSRRTRSPEPFSPLSRPPSPLSLPRPRSAPVRRPPLSAGDISFPARPHTPLSRIDVRPPLDWGPQRQTLSRPPIPRRGPFSEAGGGRPPRSPQLRTPEHRTQSTQVSSGSSTYLQLPPRPPGTQASMILLPGPPVDSTLHQSLETDTLLTKLCGQDRLLRQLQEDLDKRQEEKEQLEAALELTRQQLGQATREAAASGKAWGRQRLLQDRLVNVRAALCHLTQERERVWDTYSGLEQDLGTLRETLEYLLHLGSPQDRASAQQQLWMVEDTLAGLGGPQKQPPHTEPKSPSPAPQREESSERESLSESLELSSPQSPEVDWGQPPGGDRALSSSQSGVGSPRVSRASSPECRQQSSPLLRTKAPLARPRMSAQEQLERMRRNQACGLSLPRPTSPRLLTLGRTLSPVPRQPDMEQRPIVGAAKWLRSSGSWSSPRHSTTYSPVSGGHRERVLSLSQALATEASQWHRLMTASPERNLDTRGDCLQPSPQPPSEELPQVTSSPTSHKANSATTGFSCQGSGRGLAPWEPRWDPGKAPPALAQEEGAWPLRVTLLQSSF
What is the function of this protein?
Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 4, PH domain-containing family A member 4, Phosphoinositol 3-phosphate-binding protein 1, PEPP-1.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: TRPF_SYNJA
Sequence: MGRLFVKICGITRQDQAEAIAALGVSALGFIAVPNTPRYLPLSQARWLASLPRHVEKVGVFVDPDPRTIATWVEVGGLTAVQLHGRESPEECRQLGEWLPGIRRIKALRIRHLADLEAAHLYGDCVEALLLDAYHPQRAGGTGQTLNWPELAHRSLPLPWLLAGGLTPDNVLQALSHLQPSGIDLSSGVERQPGDKDLHKVWRLLQQLESQGWQIASALPQPNQGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: AMP11_ENCCU
Sequence: MRWIKVMAGLLPMIGSKGADEKDSSQQRRLSRVVVPEHYDLHVKILDAGFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYSNGLVGLYKSGGPKEVYSTHFEPTDARRAFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETCKMSTYLVAFVVGELSYIEDWSKDGVRLRVYGDSSEVEWGRYGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVPGKSNVEDMKNVAGTVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQDCGSSLVLSQSRYSMLGKSDDSLWTIPVVVSWEGKGQERIELRGRETTVRKRSSVYKVNAEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYYSDSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIGTSVESVSMNKYVLSVGVEVGIREAVEKVQELWRRHVEAGEELGELRWIVYKAVVDENLGYMMDKYKNGDTPGMRREVMNGFSGIKREENFLDVVGNLSQFSVEDIGVVIGSISRGGAFRDAMVEYVVSHGEELYLMVHKNAMLYNMIIMSLRHVSGDLIVEKVERFLSGIKHSGSNLSIEKVRNEIQWRRRMRGIREEVLRGLLPEAEK
What are the official names of this protein?
Probable M1 family aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
Protein: RS11_SHIBS
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: URE3_PSEF5
Sequence: MDLTPREKDKLLIFTAGLVAERRLARGLKLNYPETMAYISAALLEGARDGQTVAELMHYGTTLLSREQVMEGIPEMIPDIQVEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_FELCA
Sequence: APLEPVYPGDNATPEQMAQYAAELRRYINMLTRPRYGKRDRGETLDILEWGSPHAAAPRELSPMDV
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide prohormone.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXT_METBF
Sequence: MKIGVIAIQGAVSEHIDALRRALKERGMSAEVVAVKHKGVIPECGGIVIPGGESTTLCRLLAREGIAEEIKDASARGVPILGTCAGLIVLSKEGDEQVEKTSQELLGIMDTKVNRNAFGRQRDSFEAELEVEILDSPFTGVFIRAPGIVSCGPEVRVLSRLDDLIIAAEQGNVLALAFHPELTEDLRIHQYFLDKIFKNA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SCS7_SCHPO
Sequence: MASVTSEKCVILSDGTEYDVTNYLVANKDAADLLRRYHRQEVADILNATSKSKHSEAVVEILKSAKVPLKNKEFSDLVDQNIGVGYGNEFIVKPTDLDKDFEKNHFLDLKKPLLPQILFGNIKKDVYLDQVHRPRHYRGSGSAPLFGNFLEPLTKTPWYMIPLIWVPCVTYGFLYACTGIPFSVAITFFIIGLFTWTLVEYTMHRFLFHLDEYTPDHPIFLTMHFAFHGCHHFLPADKYRLVMPPALFLIFATPWYHFIQLVLPHYIGVAGFSGAILGYVFYDLTHYFLHHRRMPNAYLTDLKTWHLDHHYKDYKSAYGITSWFWDRVFGTEGPLFNEQGKISTKAK
What is the function of this protein?
Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids.  Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
What are the official names of this protein?
Ceramide very long chain fatty acid hydroxylase scs7, Ceramide VLCFA hydroxylase scs7.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family. SCS7 subfamily.
Protein: IRX1_XENTR
Sequence: MSFPQLGYPQYLSAGQAAVYGGERPGVLAAAAAAAAAAAAAGSGRPTGADLGSSSTAAVTSVLGMYASPYSAPNYSAFLPYTTDLTLFSQMGSQYELKDNPGVHPATFAAHTTPGYYPYGQFQYGDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKEDDNIFGSDTEGDHEKNEDDEEIDLESIDIDKIDDNDGEQSNEEEDEKLEHLRQGEKESFKKESEVMIPSSDGLKSKDSLSLGKESSDTSNTRIVSPGGQGNIQVPPHNKPKIWSLAETATSPDGALKSSPPPSQANHTSPPIQHPAFLPSHGLYTCQIGKFHNWTNGAFLTQSSLINMRSLLGVNPHHVAHHNHHHLQAHQQAPLLATNLSSLSSDKTPERTSPKHSDRENLPRTESPPQLKPSFQAVRENTLSQQEGTSRILTALPSA
What is the function of this protein?
Acts partially redundantly with other irx members in neural patterning.  Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord.  Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state.  Also up-regulates repressors that prevent neuronal differentiation.  Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes.  Acts primarily as a transcriptional repressor during neural development, and binds to the bmp4 promoter to repress gene expression and thus mediate down-regulation of bmp4 by wnt signaling.  Controls multiple processes through bmp4-repression including neural plate development, neural crest specification and Spemann organizer development.  Involved in the specification of the preplacodal field at the anterior border of the neural plate.  Regulates the genetic cascade of interactions that are necessary for positioning the isthmus organizer and the formation of the midbrain-hindbrain boundary.  Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling.  Subsequently required for proper formation of the intermediate tubule segment of the pronephros.  Acts principally as a transcriptional activator during pronephros development.
What are the official names of this protein?
Iroquois-class homeodomain protein irx-1, Iroquois homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTBC_MAIZE
Sequence: MACSGCSCEAAVGAMASEAYLEGAPVREARELVAELCRHFYAQGWVTGTGGSITVKVNDPTVPLADRLIVMSPSGVQKERMVAEDMYVMAADGKVLSAPVAKPWPNKPPKCTDCAPLFMKAYLMRGAGAVIHSHGIETCIATMLIPGAKEFRVTHMEMIKGIKGHGYHDELVIPIIENTPYEYELTDSLSEAIAAYPKATAVLVRNHGIYVWGESWINAKTQAECYHYLLDACIKLYQLGIDWTTPEHGSINNPRRPHSILSPEICNGCHAADSSKCVVLDIEGTTTPISFVTDVMFPYARDNVRKHLTSTFDFEETKEDIKLLRIQIEDDLQNGVAGAVPVPPDEGGKEEVINSLVANVESMIKADRKITSLKQLQGHIWRIGFQKKELQGVVFEDVPVALKNWHASGIKVYIYSSGSREAQRLLFGNTTYGDLRKFLCGYFDTTTGNKRETRSYFEISQSLGVDSPSQILFITDVFQEAIAAKNAGFEVIISIRPGNAPLPDNHGFRTIKSFSEI
What are the official names of this protein?
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.