PharMolix/UniProtQA huggingface dataset:
Protein: ENTP1_RAT
Sequence: MEDIKDSKVKRFCSKNILIILGFSSVLAVIALIAVGLTHNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQLLEECQVKGPGISKYAQKTDEIAAYLAECMKMSTERIPASKQHQTPVYLGATAGMRLLRMESKQSADEVLAAVSRSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLNFISDSQKQATFGALDLGGSSTQVTFVPLNQTLEAPETSLQFRLYGTDYTVYTHSFLCYGKDQALWQKLAQDIQVSSGGILKDPCFYPGYKKVVNVSELYGTPCTKRFEKKLPFNQFQVQGTGDYEQCHQSILKFFNNSHCPYSQCAFNGVFLPPLQGSFGAFSAFYFVMDFFKKMANDSVSSQEKMTEITKNFCSKPWEEVKASYPTVKEKYLSEYCFSGTYILSLLLQGYNFTGTSWDQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYISLMVLFSLVLVAMVITGLFIFSKPSYFWKEAV
What is the function of this protein?
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.  Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.  Hydrolyzes ATP and ADP equally well.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TIG_SYNSC
Sequence: MSAAALKVTTEARPSSRLAVTVTVPGERCKTSYEDAITSLSRSINLPGFRKGKVPRTVLVQQLGGVRIKATALEKLIDNAWRDAIQQESLEPISQPDLSSGFDGLLESFEPGKELTFTLEADVAPTPKLKTTKGLKAEFETVAYDASRVDAMIEDSRKQMATVVPVEGRAAQNGDIAVLGFKGTYTDDGSEIEGGSADSMDVDLENGRMIPGFIEGVIGMKVGETKTVDCQFPDDYPKEDARGRKASFEIELKDLKTRELPELDDEFAKQASEQETLADLRKDLEQRLKDDAERRQTSNRRDALVAALVEQLEVELPEALIQQESRNLLEQTAAQFAQQGMDVKSLFTPDLVRNLMQNSRPEAEERLRRSFALTALAEAEDIKLDDKAVDAKIKEVKKELSADAKIDPERLRQAVMDDLIQDRLMGWLEENSTITEKAPAADDSKAEAKKKPAAKKAEAKSKSKADAKD
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HMUS_YERPE
Sequence: MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALESVGEVKAITRNTYAVHEQVGRYENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRHGVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIPENPALQLEPLSTPEAVEPTADDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQNEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGFVTSLELFAADGTQLAQLYGQRTEGQPEQNQWREQIARLINKDIAA
What is the function of this protein?
Part of the binding-protein-dependent transport system for hemin.
What are the official names of this protein?
Hemin transport protein HmuS.
What is the protein family that this protein belongs to?
To Y.enterocolitica HemS.
Protein: PYRG_METSB
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYTVRLRKLDPYLNIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPALRDDNITTGRIYQEIIAKERRGDYLGATVQVIPHVTNAIKDFVLSGTDGVDFVLVEIGGTVGDIEGLPFFEAIRQLGNDLPRSHAIYIHLTLLPFIPSAGELKTKPTQHSVKELRSIGIQPHILLCRTDRTIPREERRKLGLFCNVRESAVIEARDVQSIYDVPRAYHAAGLDQEVLAAFGIEPAPKPDMSRWNAVMERVHNPEGEVTIAIVGKYTGLKDAYKSLIEALAHGGMANRINVRIDWIESEVFESDDPAVYLDHVHGILVPGGFGQRGAEGKILAARFARERKVPYFGICFGMQMAVIEAARSLAGVKDANSTEFGPTKEPVVGLMTEWMRGNELQIRAAESDLGGTMRLGAYRASLAPHSKIAAIYGATEISERHRHRYEVNTAYRERLAENGVIFAGLSPDGLLPETIELLDHPWFIGVQFHPELKSRPFEPHPLFASFIAAALEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YFEW_SALSV
Sequence: MKFTLVATVLLTFSLSAFAVEYPVLTTASPDQVGFDSQKLHRLDGWIQNQIDAGYPSINLLVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLASNTKMYATNFALQKLVYEGKIDVNDLVSKYIPGFKDMPGDKIKGKDKLRIIDILHHVAGFPADPQYPNKNVAGKLFSQSKSTTLEMIKKTPLEYQPGSKHIYSDVDYMILGFIVESITAMPLDRYVETTIYKPLGLKHTVFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTNTLWGQVHDEKAWYSMGGVSGHAGLFSDTHDMAVLMQVMLNGGGYGNVKLFDDKTVAQFTRRSPEDATFGLGWRVNGNASMTPTFGVLASPQTYGHTGWTGTLTSIDPVNHMAIVILGNRPHSPVANPKVNPNVFVSGLLPAATYGWIVDRIYGSLK
What are the official names of this protein?
Putative D-alanyl-D-alanine carboxypeptidase, DD-carboxypeptidase, DD-CPase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family. YfeW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRM56_THEPD
Sequence: MSTGRRVFVLRIGHRPVRDHRVTTHVGLVARAFGADGIFLEESVEESVIRTLRNVVENWGGDFKVLTTRDPRETVANWKKNGGIVVHLTMYGENISEELINLISGQGKDILVVVGGEKVPRWLFEEADFNVAIGNQPHSEVAALAVFLDRLFKGEELRREFPGAKLSIIPSKRGKIVVRRE
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STRP7
Sequence: MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: EBRB_BACAT
Sequence: MKGLLYLALAIVSEVFGSTMLKLSEGFTQAWPIGGVIAGFLSAFTFLSFSLKTIDLSSAYATWSGVGTALTAIVGFLLFGETISLKGVFGLTLVIAGVVVLNQSKAPAKEKKQTVCE
What is the function of this protein?
Part of a multidrug efflux pump.  Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O.  The efflux is probably coupled to an influx of protons.
What are the official names of this protein?
Multidrug resistance protein EbrB.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. EbrA/EbrB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPIN1_MOUSE
Sequence: MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNSSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTHPQSASYPSSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLGSRKTPDKMNFQAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSSHLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA
What is the function of this protein?
Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
What are the official names of this protein?
Phosphatidate phosphatase LPIN1, Fatty liver dystrophy protein, Lipin-1.
What is the protein family that this protein belongs to?
Belongs to the lipin family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion outer membrane. Cytoplasm. Nucleus membrane. Note=Recruited at the mitochondrion outer membrane following phosphatidic acid formation mediated by PLD6. In neuronals cells, isoform 1 is exclusively cytoplasmic (PubMed:21397848). In 3T3-L1 pre-adipocytes, it primarily located in the cytoplasm (PubMed:16049017). SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm. Endoplasmic reticulum membrane. Note=Nuclear localization requires both CNEP1R1 and CTDNEP1 (PubMed:22134922). In neuronals cells, localized in both the cytoplasm and the nucleus (PubMed:19753306). In 3T3-L1 pre-adipocytes, it is predominantly nuclear (PubMed:16049017). Translocates from the cytosol to the endoplasmic reticulum following acetylation by KAT5 (By similarity).
Protein: DCD_LEGPA
Sequence: MSIKSDRWIEKMALEHGMISPFQAGQVRENQNGRIISYGVSSYGYDVRCSNEFKIFTNINSAIVDPKAFDENSFVDVQSDVCIIPPNSFALARTVEYFRIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYAYEGVAQMLFLEANEVCAVSYRDRNGKYQGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: HEM6_SCHPO
Sequence: MSDITVEPIGKQMEKLILDVQQEIVAGLEAVDGQKFFQDKWTKGEGGYGISCVIQDGNVFEKGGVNTSIVQGKLNQDAVQRMRANHEGIDRTAKELPFFAAGISMVIHPRNPMAPTTHLNYRYFELVNSDGKKIWWFGGGADLTPSILFEEDGKHFHKLHKEACDRHDPTFYPRFKKWADEYFLIKHRKETRGIGGIFFDDLSEKDPQELFAFVKDCAHTFLPAYVPIMEKRKNMEFTEDDKEFQLIRRGYYAEFNVMYDRGTWFGLQAPEPRVESILMTLPLHASWRYKYEPKQERHKALLKVTHTPIEWC
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).
What are the official names of this protein?
Probable oxygen-dependent coproporphyrinogen-III oxidase, COX, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_NEPAB
Sequence: MSPIYINLMMAFIFSLLGTLLFRSHLMSTLLCLEGMMLSLFIMVTSSALNTQSMITYVIPITMLVFGACEAAIGLALLVMISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IND11_ECOLI
Sequence: MWTGKKVDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI
What is the function of this protein?
Involved in the transposition of the insertion sequence IS2.
What are the official names of this protein?
Transposase InsD for insertion element IS2-11.
Protein: RPIA_METM7
Sequence: MARTKKANDEVPTDSDSLKLKVAKQAAKLVKDEMVVGLGSGSTANLFIQELGKRIVEEELYIYGVPTSFDSRMVASTAGIPLISLDQCGEIDLAIDGADEVCKSTLALIKGGGGCHTMEKIVDYYAKEFIVLADEGKLVDSLGDKTPVPLEVIPFAYSTVLNKLLKLNTAPAIRSGSGKMGPVITDSGNMIIDVFMSIEDAEETEIMLNNIPGVLENGVFSKCDKVLVGTSKKVEILKK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: ALLB_SALCH
Sequence: MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLEEAKNVLDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKAAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQPDSSYVLKNEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: FCHO2_PONAB
Sequence: MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSTTQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEVIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELRVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNERGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVMNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC
What is the function of this protein?
Functions in an early step of clathrin-mediated endocytosis.  Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits.  Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane.  Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles.  Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor (By similarity).
What are the official names of this protein?
F-BAR domain only protein 2.
What is the protein family that this protein belongs to?
Belongs to the FCHO family.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Associated with forming but not mature clathrin- coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2 (By similarity).
Protein: RNC_SPHAL
Sequence: MSDPLNTEALADIIGCIPDDLTLYDLALTHGSTGRADYQRLEFLGDRVLGLVLASELYTRFPAASEGEMSSRLHVLASGATCAAIAQRLDLPALIRFGAQARSDGGRHSDNIAADAIEALIGALFLERGIEAARTFILAQWGALIDGQQAAPKHPKAALQEWALARGRRPPEYEIVSREGPDHAPRFRIAVSIGKLARAEAQGASKQAAEKAAAAALLAELEGQEK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS42_HUMAN
Sequence: MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
What is the function of this protein?
Plays a role in spermatogenesis.  Involved in germ cell survival during meiosis.
What are the official names of this protein?
Putative serine protease 42, Serine protease 42, pseudogene, Testis serine protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RIBA_ACIBC
Sequence: MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFNEQYLKTKRERMDHLYQKDDF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: ARGB_DESRM
Sequence: MISPLEKAGILVEALPYIKKFSGKTIVIKYGGHAMLNADLKKAVMTDLVLMKFVGINPVVVHGGGPEITGMLHRLGIESQFVSGLRVTDAPTMEVVEMVLGKLNKEIVALINGLGGRSVGLSGKDANLIMANKKYSNDCQDIGFVGEVTGVNPQLLQTVIQEGYIPVVSPVGISTEGETYNINADTVASAIATALKADKLIILTDVEGILEDRQDKGTLISTVKMEDIPRLIERGVIQGGMIPKVECCMQAIQTGVATTHILDGRVPHSILLEVFTDKGIGTMVVSD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_RHIWR
Sequence: MPKILVLYYSTYGHIETMAEAIAEGARSAGAEVDVKRVPETVPLDIAEKNHFKLDQKAPVATVAELEDYDAIIVGTGTRFGRMSSQMAAFLDGAGGLWARGALNGKVGAAFASTATQHGGQETTLFSIITNLLHFGMTIVGLPYAYQGQMGVDEVKGGAPYGATTIADGDGSRQPSATDLDGARFQGRHVAEITAKLVG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: UBIE_YERPN
Sequence: MVDQEKETTHFGFRTVAKEQKEGMVAEVFHSVAAKYDLMNDLMSFGVHRIWKRFTVDCSGVRRGQRVLDLAGGTGDLTAKFSRLVGEQGEVILADINESMLRMGREKLRDKGIVGNVSYVQANAEALPFPDNYFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPLLEPLSKAYDAYSFHILPKIGELVAQDAESYRYLAESIRMHPDQETLKGMMADAGFENVTYSNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RL7_CLOBH
Sequence: MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAGAGAAEEKTEFDVVLADAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DXS_BACAC
Sequence: MDLTQIQNPSFLKDMSISELEGLSEDIRKFLIEELSQTGGHIAPNLGVVELTIALHKLFDSPKDKFLWDVGHQSYVHKILTGRAKEFGTLRQYQGLCGFPKRCESEHDVWETGHSSTSLSAAMGMALARDLKKTKEYVIPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNVLGRLRTAGKYHWVKDELEYILKKIPAVGGKVAATAEKIKDSLKYLLVSGVFFEELGFTYLGPVDGHDYEKLFETLQYAKKTKGPVLVHVITKKGKGYKPAESDVIGTWHGTGPYKIESGDFVKPKEVAPAWSAVVSETVLKLARTDERIVAITPAMPVGSKLEKFQKEFPDRMIDVGIAEQHATTMAAGMATQGMKPFLAIYSTFLQRAYDQVVHDICRQNLNVFIGIDRSGLVGADGETHQGVFDISFLRHLPNMVIMMPKDENEGQHLVYTAMQYEDGPIALRYARGNGLGVHMDEELKAIPIGSWETLKEGTQAAILTFGTTIPMAMEAAERLEKAGVSVKVVNARFIKPMDEAYLHDLLGKNIPILTIEEACLIGGFGTGVVEFASENGYHSALVERMGIPDRFIEHGSVTKLLEEIGLTTDAVVDRIHTMIPSKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: FIEF_SALDC
Sequence: MNQTYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLFLTSIQNLIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILQRFPGSDVIIHQDPCSVVPREGRKFELV
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FHP_CANNO
Sequence: MSAAKQLFKIVPLTPTEINFLQSLAPVVKEHGVTVTSTMYKYMFQTYPEVRSYFNMTNQKTGRQPKVLAFSLYQYILHLNDLTPISGFVNQIVLKHCGLGIKPDQYPVVGESLVQAFKMVLGEAADEHFVEVFKKAYGNLAQTLIDAEASVYKTLAWEEFKDFRVTKLVKEAEDVTSVYLTPVDGFKLKPIIPGEYISFRWDIHNPDITDIQPREYSISQDVKENEYRISVRDIGIVSDYINKKLQVGDIVPVHAPVGTMKYDSISKKGKVAVLAGGIGITPMIPIIEHALKDGKDVELYYSNRSYQSEPFREFFSNLEKENNGKFKLNNYISAENQKLQVKDLEHINPDEYDVYLLGPVAYMHEFKTYLVGKGVSDLKMEFFGPTDPDC
What is the function of this protein?
In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2).  Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities.  However, all these reactions are much lower than NOD activity (By similarity).
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GKN2_RAT
Sequence: MKSLVAFLVVLSILRIQSQAKEVFNIFVPGNNGGNVQETVTIDNQENTATINIHSGSCSSTTIFDYKHGYIASRVLSRRACYIIKMDHKAIPALDKLQRFLYEKQTMNAMASTEYTWVKYNPLKSLITKVDWFLFGSPIEQLCKHIPLYEGEVATKPREVGTGGCAKVGILGILGISICGGIHL
What are the official names of this protein?
Gastrokine-2, Blottin.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOB_LIMRD
Sequence: MSYKRVFVIVMDSVGTGAAHDAAKFDDVGSDTLGHVGEYYKGALKLPNLGKLGISNLRDTPIEGVPVADPAIGDYGKMEEISAGKDSMDGHWEMMGLPVMKPLSTFPNGFPQEIVDKLEKFSGRKVIVNKPYSGTEVIHDYGERQMETGELILYTSGDSVMQIAAHEDVIPVEELYKICEYARTLVNGPEYTVGRIIARPYVGPDKDHFTRTANRHDFSLKPIGETDMDRLRAAGYDVIGVGKINDIFSGEGIDKGYHNESNMDGMDHVDEVMKQDFTGFCFTNLVDFDAMYGHRRNPKGFGQALMDFDKRLGNVLDEMKPDDLLMITADHGNDPGFKGTDHTRENVPLLVYSPSMNKPNQSLGVRKTFSDLGATILENFNVEPVKGTSFYKEISND
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.