PharMolix/UniProtQA huggingface dataset:
Protein: TX701_LYCSI
Sequence: MKLIIFTGLALLLIVSLIDVEAQNEGACLPRGSVCTTNHAGCCSKLSCDCYRRFEKGVEKGQKCWCIPTGLRYSKEKE
What are the official names of this protein?
U7-lycotoxin-Ls1a, Toxin-like structure LSTX-G1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 07 (U7-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FRK_MOUSE
Sequence: MGSVCVRLWAYLQPFLPCWSQEADKSVVIENPGAFCPPEAPRSQEPERSHGQYFVALFDYQARTAEDLSFRAGDKLQVLDTSHEGWWLARHLEKKGTGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETLHWKLEDYFETDCSYSDTNNFIN
What is the function of this protein?
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation.  Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4.  May function as a tumor suppressor (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Protein: PROB_SALA4
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAGEITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_UREP2
Sequence: MAVSKQQKHDLTVKFGGSASNTGKTEVQVAILSAEIDSLTTHMIENKKDKASKRGLYKKVAQRKKLLSYLQRVDIERYRALIKELNLRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MIAB_PSESM
Sequence: MAKKLYIETHGCQMNEYDSSRMVDLLGEHQALEVTARAEDADVILLNTCSIRERAQDRVYSQLGRWRELKLANPEMVIAVGGCVASQEGAAIRDRAPYVDVVFGPQTLHRLPEMIDAARITRLPQVDVSFPEIEKFDHLPEPRVDGPSAYVSVMEGCSKYCTFCVVPYTRGEEVSRPFDDVLTEVTHLAEHGVREVTLLGQNVNGYRGTTHDGRVADLADLIRAVAVVDGIDRIRYTTSHPLEFSDSLIQAHADVPELVKHLHLPVQSGSDRILAAMKRNHTTLEYKSRLRKLRAAVPGISISSDFIVGFPGETEKDFDNTMKLIEDAGFDFSFSFIYSPRPGTPAADLKDDTPEALKKERLAALQHRLNQQGFEISRQMVGSIQRILVTDYSKKDPGELQGRTENNRIVNFRCDNPRLIGQFADVHIDDAQPHSLRGSLLQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHCO_ECOL6
Sequence: MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMNDVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH
What are the official names of this protein?
Uncharacterized protein YhcO.
What is the protein family that this protein belongs to?
Belongs to the barstar family.
Protein: Y1327_CLOK5
Sequence: MENDVSSLMLEDEKGDKVKFQVVTKFDIEDREYIIVVPEENEDSKEAIVLKIVEGEDGREAFITVEDDEEFNQVSEVYEALFND
What are the official names of this protein?
UPF0473 protein CKL_1327.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: DGTL1_RHIL3
Sequence: MTIDTRALGFGSSERAVYAADPWTTRGRLYQEDGSPTRSDFQRDRDRIVHTTAFRRLKHKTQVFIAQDGDHYRTRLTHTIEVAQIARALARALKLDEDLAEGVALVHDFGHTPFGHTGEDALHEVLLPYGGFDHNAQSLRIVTKLERRYAEFDGINLTWESLEGLVKHNGPLLTADGVGTRGPVPQPILDYCELHDLELATYASLEAQVAAIADDIAYNTHDIDDGLRSGYLTFDMLEEIPFLAGLMAEVRARYPHLEPSRFTHEIMRRQITRMVEDVIGVAQQRLSLLRPESAADIRAADRVIATFSEGMAETDRQIKAMLFKRIYRNPDIMRIRAGAAQIVTDLFAAYMANPKEMQSHYWVDHIAGLSDAPKARHVGDYLAGMTDTYAISAHRRLFDHTPDLR
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: CH602_STRAW
Sequence: MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPMALKRGIEKAVEAVSGALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIANSKISSVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGEVISEEVGLKLENASIDLLGRARKVVITKDETTIVDGAGSADQVAGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALIQASSVFEKLELTGDEATGANAVRLALEAPLKQIAVNGGLEGGVIVEKVRNLPVGHGLNAATGEYVDMIAEGIIDPAKVTRSALQNAASIAALFLTTEAVIADKPEKAAAGGAPGGMPGGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJT_ECOLI
Sequence: MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQLANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVPVKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMRDMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQFEHFMAVSGKRRWLIPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTALRALIPQRLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKTSASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVDSWKVIVVEPEKQLTLLFGMKAPGLGRLCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWLLMIPAHLFIFRGMAKQIARLAEQSTD
What are the official names of this protein?
Putative NAD(P)-binding protein YbjT.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UPP_BURP6
Sequence: MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRANDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERLMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ACP_PROM5
Sequence: MSQEEILQKVCSIVSEQLSVESGEVKSDSNFQNDLGADSLDTVELVMALEEAFDIEIPDEAAEGIATVGDAVKFIEAKKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPT_SERMA
Sequence: MRNISLTTTIITTTDTTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: IMDH_TRIFO
Sequence: MAKYYNEPCHTFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIALAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNTVAVTDDGTPHGVLLGLVTQRDYPIDLTQTETKVSDMMTPFSKLVTAHQDTKLSEANKIIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTRDFRERVPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSRARNWQRYDLGGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGALTIPQLQSKAKITLVSSVSIVEGGAHDVIVKDRINDYHPK
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.  Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP143_MYCBO
Sequence: MTTPGEDHAGSFYLPRLEYSTLPMAVDRGVGWKTLRDAGPVVFMNGWYYLTRREDVLAALRNPKVFSSRKALQPPGNPLPVVPLAFDPPEHTRYRRILQPYFSPAALSKALPSLRRHTVAMIDAIAGRGECEAMADLANLFPFQLFLVLYGLPLEDRDRLIGWKDAVIAMSDRPHPTEADVAAARELLEYLTAMVAERRRNPGPDVLSQVQIGEDPLSEIEVLGLSHLLILAGLDTVTAAVGFSLLELARRPQLRAMLRDNPKQIRVFIEEIVRLEPSAPVAPRVTTEPVTVGGMTLPAGSPVRLCMAAVNRDGSDAMSTDELVMDGKVHRHWGFGGGPHRCLGSHLARLELTLLVGEWLNQIPDFELAPDYAPEIRFPSKSFALKNLPLRWS
What are the official names of this protein?
Putative cytochrome P450 143.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: NHAA_NITHX
Sequence: MRVRFGQYPNCGKRMVLEPGRLRPYSILRSFLDSEASAGLTLMFVAALALLLANSPFAPVYFDVLHRQVLGLTVLHWINDALMAVFFLLVGLEIKREFLDGQLATWSRRALPGIAALGGMVVPAVIFIAVNGGEPANLRGWAIPSATDIAFALGVLSLLGPRVPVSLKIFLTALAILDDLGAVLIIALFYTAELTPLMLILAAATLLGLAALNRFGVKPLAPYLVLGVVLWFFVLQSGIHATLAGVALALAIPLQASTGGGPTSPLHRLEHALNPWVAFLIVPVFGFANAGVSFAGLGLSALLDPVPLGVALGLFFGKQVGVFGFAWLAIWLKIADMPRYASWAHLYGVAVLCGIGFTMSLFIGLLAYPESAVLQDETKIGVLLGSTLAGLIGWLILRVTKAGFPERT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EF2_AERPE
Sequence: MGARVKVVSEIEKIMRNIDQIRNIGIIAHVDHGKTTTSDSLLAAAGIISERIAGEALVLDYLNVEKQRGITVKSANVSLYHEYEGKPYVINLIDTPGHVDFSGKVTRSLRVLDGAIVVVDAVEGVMTQTETVIRQALEERVRPILFINKVDRLIKELKLPPEKIQQRFVEIIKEVNNLIDLYAEPEFRKKWKLDPNAGMVAFGSAKDKWGISVPQVKKKGITFREIIQAYEKGKEAVAELSKKMPLHETLLDMVIKFVPNPREAQRYRIPKIWKGDINSEIGQAMLNADPDGPLVFFINDVRIEKAGLVATGRVFSGTLRSGEEVYLLNAGKKSRLLQVSIYMGPFREVTKEIPAGNIGAVMGFEDVRAGETVVSLGYEENAAPFESLRYVSEPVVTIAVEPVKIQDLPKMIEALRKLTIEDPNLVVKINEETGEYLLSGMGPLHLEIALTMLREKFGVEVKASPPIVVYRETVRQQSRVFEGKSPNKHNKLYISVEPLNEETITLIQNGAVTEDQDPKDRARILADKAGWDYNEARKIWAIDENINVFVDKTAGVQYLREVKDTIIAGFRLALKEGPLAAEPVRGVKVVLHDAVIHEDPVHRGPGQLYPAVRNAIWAGILDGRPTLLEPLQKLDIRAPMEYLSNITAVLTRKRGRIINVETTGVMARIIAAIPVAESFDLAGELRSATAGRAFWGVEFYGWAPVPDQMLQDLIAKIRQRKGLPPSPPKIDDLIGP
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NXPE2_MOUSE
Sequence: MRRMLSPRILLSSLPNASARKLFLIVLIIFVFWVVFMTSKDHTEFMVHLNNRIILRRWSIFKEFLHSEELKNTPASVEAELAVTAILEKLNQQIPPRPFQTHSSTTSAKQSTATIHNPQRTYCVGDQLNVLLVAKDYFGNRKEYGGDFLRARIFSPAMKAGTSGKVTDFNNGTYLVSFTLFWEGPVSLSILLMHPSEGVSALWRARNRGYGKIIFTGQFLNGTSPVLTECGLTLNTSAELCQYLDARDHEAFYCLKLPGVPCEALTHMTSKNSNISYLSLEEKLLFRRFNIGVEVVKNLSIVVSLCNNKTNKKKKKCQIGMETPSPGGYTLKGRWITAHCEQNEFRAIKDINNCLTRKLIYLMGDSTLRQWIYYLPKVVKTLKYFDRHGAGPFKTHILLDTERHIFVQWKKHSHPFVTNKLFSMKDDNYIPREIDQVAGDSGTAIVISFGQHFRPFPINVFIRRAINVKNAIERLFLRSPETKVIIKTENIREINEHVEIFSDFHGSIQNLIIRDIFRDLNVGIIDAWDMTVAYRSEDVHPPESVIESQIGMFLNYIC
What are the official names of this protein?
NXPE family member 2, Protein FAM55B.
What is the protein family that this protein belongs to?
Belongs to the NXPE family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THIC_MYCA1
Sequence: MTAIVEPSVTTGPIAGSSKVYRELDGVPGARVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLTAGLPARPGRVRDRGTQLQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTLGELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMADKSREFAEHGNRVYLPLAQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: GON2_CHICK
Sequence: QHWSHGWYPG
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH-II, Luliberin II, Luteinizing hormone-releasing hormone II, LH-RH II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL4_THEAC
Sequence: MNTKVPIYSVSGEMKGEIDLPEVFDTEVREDIIRRAFRAISLSMRQPYGSSPLAGMRRVGHTTRPGLGISRMPRIAGGSRVVGIASAVGGKSAHSPRTTKNLYVKINDRERKMAKYSAIALTASVEAVKKRGHRFKEGLKLPIVVEDGVEGINKTKDAIALLKNLGVYEDIERSREGKHIRAGRGKMRGRRYKQPKSVLIVARNSSAMKAFRSLPGVDIASPNSLSIRKLAPGGVGGRLTIFTEGAIESLKEVDQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS19_THEVB
Sequence: MGRSLKKGPFVADHLLRKIEALNERNAKEVIKTWSRASTIVPEMIGHTIAVHNGKQHVPVYITEQMVGHKLGEFAPTRNFRSHVKGDKKARH
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PA2A_OPHHA
Sequence: MNPAHLLVLSAVCVSLLGASSIPPQPLNLLQFNYMIQCTIPGSRPFLDYMDYGCYCGTGVAGHPVDELDRCCQTHDLCYSKAEEQPKCSSLLNSPLMKKYSYTCSGGTLTCNDDNDECGAFICNCDRAARICFAGAPYNKENKELDIATRCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRMA_AGRFC
Sequence: MSEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFRERVSTLLAPAFPGLVIEKEIIPDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAIEIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGTGSGVLAIAVRKMRPIPVLATDIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQLVTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM32_YEAS8
Sequence: MLRITVKTLQQRASFHHSFKHISVPDLHTRAQNDQTNCYCQEINARLPSKTDPLDPHIKLPHRTPNYNKHVLLLSPGDRFAQPWKVAWNHNLDTNTNRPYNAISKLRSHLGGSPGILINAVHLQNEFIPRPKQHDEWLYFFVIPDMKLYVIKETDIEEFASFLDEGAIQAPKLSFQDYLSGKAKASQQVHEVHHRKLTRFQGETFLRDWNLVCGHYKRDAKCGEMGPDIIAAFQDEKLFPENNLALISHIGGHIFAGNVIFYKLFGREKMQNKLDSLWFGKVYPHNLKLLCENLENGKIIDEMYRGGISMN
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: RL7_ACAM1
Sequence: MSATEEILEKLKSLTLLEAADLVKQIEETFGVSAAPAAGVMMAAPGAGGAAGGEEAEEKTEFDVVLEEVPSDKKIAVLKVVRTLTGLGLKEAKEMVESTPKSIKEGVSKEDAEEAKKSLEDAGGKASLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SFTPA_HORSE
Sequence: MLLCSLTLTLILLAVSGTKCDVKEFCAACSGVPGIPGSPGLPGRDGRDGVKGDPGPPGPIGPPGGMPGSPGHDGLIGPPGPPGERGDKGEPGERGPPGPPAYPDEELQTTLHDIRHQILQLMGALSLQGSMLAVGEKVFSTNGQVVDFDAIRESCARAGGRIAVPKSLEENAAIASLVTKHNTYAYLGLEEGPTAGDFYYLDGAPVNYTNWYPGEPRGRGKEKCVEMYTDGQWNDRSCLQYRLAICEF
What is the function of this protein?
In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
What are the official names of this protein?
Pulmonary surfactant-associated protein A, PSAP, PSP-A, SP-A.
What is the protein family that this protein belongs to?
Belongs to the SFTPA family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: IHFA_YERPE
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PEPT_STRA5
Sequence: MSYEKLLERFLTYVKINTRSNPNSTQTPTTQSQVDFALTVLKPEMEAIGLKDVHYLPSNGYLVGTLPATSDRLRHKIGFISHMDTADFNAENITPQIVDYKGGDIELGDSGYILSPKDFPNLNNYHGQTLITTDGKTLLGADDKSGIAEIMTAMEYLASHPEIEHCEIRVGFGPDEEIGIGADKFDVKDFDVDFAYTVDGGPLGELQYETFSAAGLELTFEGRNVHPGTAKNQMINALQLAMDFHSQLPENERPEQTDGYQGFYHLYDLSGTVDQAKSSYIIRDFEEVDFLKRKHLAQDIADNMNEALQSERVKVKLYDQYYNMKKVIEKDMTPINIAKEVMEELDIKPIIEPIRGGTDGSKISFMGIPTPNLFAGGENMHGRFEFVSLQTMEKAVDVILGIVAKD
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I73A5
Sequence: MEQEQDTPWTQSTEHINIQKKGSGQQTQRLGRPNLTQLMDHYLRIMSQVDMHKQTVSWKQWLSLKNPTQGSLKTRVLKRWKSFNKQGWTD
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: MOAC_BACC0
Sequence: MSSFTHFNDQGRAKMVDISDKKATVRTAIACSSIVVTKEIYDKISHNEIGKGDVLAVAQIAGIMAAKRTSDIIPMCHPLLLKGVDVSFDWKQSDEQYRLLIEVKVKTEGSTGVEMEALTAASATALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYTRKS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: MTRB_METM7
Sequence: MDIVKVCPELHIVMDVDSGLIAEMRKDILVVDLHPVEDEINKLAQYAKALENSLDPRNSPMKAYNGREGTYKLAGMFQGMFFGFWVTMAILVLVTILAVKMNLSLIGL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit B, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B.
What is the protein family that this protein belongs to?
Belongs to the MtrB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.