PharMolix/UniProtQA huggingface dataset:
Protein: RNY_LATSS
Sequence: MNLDLLLILTAVIMLIVGFAVGAILQKKAHEREIDGANKTAKGIIELAEKEAATRKKEILLEAKDENHQYRSEIENELKDRRGEVQKQENRLIQREETMDRKDATLDKKERTLEEHESRLAEQAQQLKEKQAEVETLVEQQRTKLQEIAELSHDDAQKIILDETKRNLDHERAVLIKESEESAKEHADRTAKTLVAEAIQRSAADMVAETTVTVVTLPNDDMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVDKSRKEMDEQIRQIGEQAIFDVGIHTMHPDLIKILGRLHFRTSYGQNVLNHSIEVAKLTGILAAELGEDVTLAKRAGLLHDIGKALDHEVDGSHVEIGVELATRYKEPATVINAIGSHHGDIEATSIISVLVAASDAISAARPGARSESLENYIHRLEKLESITNSFKGVDHSFAIQAGREVRVIVKPEQVTDDQATVLARDVKNQIEDQLEYPGHIKVTVIRETRTVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GREA_BRADU
Sequence: MEKVPMTSAGFAALGEELKKRQSEDRPRIIEHIAEARSHGDLSENAEYHAAKEEQSHNEGRIAELEDKLARADIIDISKLSGDTIKFGATVTLVDEDTEKKAVWQIVGEVEADAKKGRISITSPLARALIGKKKGSTVEVNAPGGAKAYEITKVEWR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: FLIE_YERE8
Sequence: MSVQGIEGVLQQLQVTALQASGSAKTLPAEAGFASELKAAIGKISENQQTARTLAQNFELGVPGVGINDVMVNMQKSSVSLQLGIQVRNKLVAAYQDVMNMGV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: ISPDF_BRUO2
Sequence: MQAQSLAEVTVISKAAAVIVAAGRGERAGQSAEGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEKHENVILVTGGPTRQESTRLGLLALKDEAPQYVLIHDGVRPFIGQDLLERIIANLTPDNGVLPALAVSDTLKRAAADGMVETTISRTGLFAAQTPQAFPYAPILDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDHAVFPDIRTGNGYDVHSFEPGDHVTLCGVKIPHEAKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIANVDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATATVIYPGEVPE
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: BPP_VIPAS
Sequence: QGWPGPKVPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent.
What are the official names of this protein?
Bradykinin-potentiating peptide, BPP, Angiotensin-converting enzyme inhibitor.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL5_THETH
Sequence: MPLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDARILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWIFLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDALRGMDIAVVTTAETDEEARALLELLGFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (forming bridge B1b) connecting the head of the 30S subunit to the top of the 50S subunit.  The bridge itself contacts the P site tRNA and is implicated in movement during ribosome translocation.  Also contacts the P site tRNA independently of the intersubunit bridge; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (By similarity).
What are the official names of this protein?
50S ribosomal protein L5, TL4, TthL5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MATK_ARPGI
Sequence: RIFRLKKDIFRQQNFVYPLLLQEYIYSLAHYHSFNSLIFYEPVEIIGYDNKFSLVLVKRLITRMYQQKSLISSVNDSNQNEFWGHKNSFSSHFSSQMVSEGFGVILEIPFSSRLVSSLEEKRIPKSQNLRSIHSIFPFLEDKLLHLNYVSDLLIPHPIHLEILVQILQCWIKDVPSLHLLRLFFHEYHNLNSLITSKKSIYVFSKRKKRFFWFLHNSYVYECEYIFLFLRKQSSYLRSISSGVFLERTHFYGKIEYLTVVCCNSFQRILWFLKDTFIHYVRYQGKAILASKGTLILIKKWKFHLVNFWQSYFHFWFQPYRIHIKQLPNYSFSFLGYFSSVLKNPLIVRNQMLENSFLINTLTTKLDTIAPVISIIGSLSKAQFCTVLGHPISKPIWTNLSDSDILDQFCRICRNLCRYHSGSSNKQVLYRIKYILRLSCARTLARKHKSTVRTFMRRLGSGFLEEFFLEEEQSLSLIFLQKIPFPLHGLHRERIWYLDIIRINDLVDHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SP5G_EXISA
Sequence: MQITDVKIRKVATEGRMKALASITLDHEFVVHDLRIIEGSSGLFVAMPSKRTPEGIFRDIAHPINGEMRQKVEAAVLETYSNMDVEILDPQHVSYGTHE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: SCED1_STAS1
Sequence: MKKTVVASTLAVGLGVTGFAAGNSADASEQGVDKAQLAQQAQSNPESLNAAPVQDGAYDINFNYNNTDYSFQSDGQYWTWSYGQGSTNAPAQETAEQPQLVEQPQQTEQASTEQPAQEAAPQTEETQQPQQEATTQTTSSSNESTSNESSSSEASEGSSVNVNSHLQAIAQRESGGDLKAVNPSSGAAGKYQFLQSTWDSVAPSEYQGVSPTEAPEAVQDAAAVKLYNTAGASQWVTA
What is the function of this protein?
Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells.
What are the official names of this protein?
Probable transglycosylase SceD 1.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. SceD subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSZ_BACSU
Sequence: MLEFETNIDGLASIKVIGVGGGGNNAVNRMIENEVQGVEYIAVNTDAQALNLSKAEVKMQIGAKLTRGLGAGANPEVGKKAAEESKEQIEEALKGADMVFVTAGMGGGTGTGAAPVIAQIAKDLGALTVGVVTRPFTFEGRKRQLQAAGGISAMKEAVDTLIVIPNDRILEIVDKNTPMLEAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIMSNKGSALMGIGIATGENRAAEAAKKAISSPLLEAAIDGAQGVLMNITGGTNLSLYEVQEAADIVASASDQDVNMIFGSVINENLKDEIVVTVIATGFIEQEKDVTKPQRPSLNQSIKTHNQSVPKREPKREEPQQQNTVSRHTSQPADDTLDIPTFLRNRNKRG
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: NQO2_THET8
Sequence: MGFFDDKQDFLEETFAKYPPEGRRAAIMPLLRRVQQEEGWIRPERIEEIARLVGTTPTEVMGVASFYSYYQFVPTGKYHLQVCATLSCKLAGAEELWDYLTETLGIGPGEVTPDGLFSVQKVECLGSCHTAPVIQVNDEPYVECVTRARLEALLAGLRAGKRLEEIELPGKCGHHVHEVEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 2, NADH dehydrogenase I chain 2, NDH-1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPF_NICSY
Sequence: MKNVTDSFVSLGHWPSAGSFGFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILNTIRNSEELRGGAIEQLEKARSRLRKVESEAEQFRVNGYSEIEREKLNLINSTYKTLEQLENYKNETIQFEQQRAINQVRQRVFQQALRGALGTLNSCLNNELHLRTISANIGMLGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KAD1_ORYSJ
Sequence: MAAVQRLLRASASGGAAAAAAAARRRMSTAVAPEQTPAAAAFPFAAAAGRARQRVAEERNVQWVFLGCPGVGKGTYASRLSRLLGVPHIATGDLVRDELASSGPLSVQLAEIVNQGKLVSDEIIINLLSKRLKKGEEQGESGFILDGFPRTVKQAEILDGVTDIDMVVNLKLREDVLVEKCLGRRICGQCGKNFNLACIDVKGENGLPPIYMAPLLPPNNCMSKLITRADDTEEVVRNRLQIYNDMSQPVEGFYRQQGKLLEFDLPGGIPESWPKLLHVLNLEDQEEMKLATA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Probable adenylate kinase 1, chloroplastic, Adenylate monophosphate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_LAMGT
Sequence: MASLRKIHPLMKITNDMVIDLPAPSNISVWWNFGSLLGLCLFSQILTGLFLAMHYTSDISTAFSSVVHTCRDVNYGWFIRSLHANGASFFFICIYLHIARGLYYGSYLYKETWTIGVVLLGLVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGGTLVQWIWGGFSVDNATLTRFFTFHFLLPFIIAAATLVHLLFLHETGSNNPTGLNSDADKVSFHPYFSYKDLLGFLALLSALTSLALFSPNLLGDPDNFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLVLVPILHTSKQRGLMFRPLTQTLFWTLVADMLILTWIGGMPVEYPFVIIGQVASTLYFLLFLVLAPTAGWLENKSLKWL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSGB_FRACC
Sequence: MTIRHDSITAELALRLVVPGGAPVPVAATVRYEPADPYAISIGFRTGADEVVEWTFARQLLSDGVRRPAGDGDVQVWPAAQSGGRIVCLSLSSPSGHALFEMPRSEVLAFLRRTYSAVPLGGESDIIDLDAELALLIWGGPER
What is the function of this protein?
Involved in sporulation-specific cell division (PubMed:19567872).  Required for early stages of sporulation.  Important in the process of growth cessation prior to sporulation-specific cell division.  Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation.  Stimulates polymerization and filament length of FtsZ in vitro (By similarity).
What are the official names of this protein?
Sporulation-specific cell division protein SsgB, Sporulation of Streptomyces griseus-like protein B, SsgA-like protein B, SALP B.
What is the protein family that this protein belongs to?
Belongs to the SsgA family.
What are the subcellular locations of this protein?
Cell septum. Note=Localizes to the divisome in sporogenic aerial hyphae in a ladder- like manner. Temporospatial localization is controlled by SsgA and it colocalizes with SsgA in presporulation foci. Localizes to the septum sites prior to FtsZ and after that colocalizes with FtsZ at the divisome throughout cell division.
Protein: PGDAE_HELPG
Sequence: MAKEILVAYGVDIDAVAGWLGSYGGEDSPDDISRGLFAGEVGIPRLLKLFKKYHLPATWFVPGHSIETFPEQMKMIVDAGHEVGAHGYSHENPIAMSTKQEEDVLLKSVELIKDLTGKAPTGYVAPWWEFSNITNELLLKHGFKYDHSLMHNDFTPYYVRVGDSWSKIDYSLEAKDWMKPLIRGVETNLVEIPANWYLDDLPPMMFIKKSPNSFGFVSPRDIGQMWIDQFDWVYREMDYAVFSMTIHPDVSARPQVLLMHEKIIEHINKHEGVRWVTFNEIADDFLKRNPRKK
What is the function of this protein?
Catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection; this likely contributes to pathogen persistence in the host.  The exact nature of the residue in PG that is deacetylated has not been determined.  Is also able to catalyze the deacetylation of acetylated xylan, and, to a lesser extent, that of chitin and chitosan.  Therefore, this enzyme might play a role during infection, considering that xylan-containing carbohydrate structures are among those commonly consumed by humans (By similarity).  In vitro, does not show activity on N-acetylglucosamine (GlcNAc), chitotriose (GlcNAc3), some N-acetyl-dipeptides and allantoinase.
What are the official names of this protein?
Peptidoglycan deacetylase, PG deacetylase, Acetylxylan esterase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
Protein: SYE_SALSV
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_MYCGE
Sequence: MKYILAIDFGLKKIGTAIANTLDKYPSAFHVFEVKNNFKTAVNNLFLRIKNDGYELEKIVIGFPKFHYYSDIQKAIKSFKQLLEKRFNLPIILVDESNTTSAVKDKLITMDLKHKDFKKAKDTLAAVLILERFFQNYH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROS1_CAEEL
Sequence: MSSGLPSIAATAQPSANGFSFNNGFPPFGIYYSQLPPVNSNGSTPNSSNRFKVKRHRQRVDAGEPRNTYQGASTSVSSNSSSSSSTSNTNSTPSSSSTSSKKSTEGMTETETMTASIEQEKVIQNEESEAGKDGMEEHDDGMNDFEIIDDTNDEVEESEERESPESNSSSASKRKSFQPQKIGEELGIEFGDETEQINVTVGGTEEAEETTDEAEGRELSALQAQLQNGHIAEQQRRFYAAFLDQQRKQVAAAQILHNGKINIERLVSSVKGDLVTNFMKDLEKVIRDWAADEVLKQEAAAPPQIPQPPPQFHPIFPANPLFHMAPPHHPVAGGGIFPPNFNAFNAFNALRRNLQDVDTSSEMKKKRTKVEIKKEDAMSSRASPLSASASPPLSRFFPAPTMVGHYGGMNFGDREDSPTNSDELSECGYEGGGSSSMLTPMHLRKAKLMFFYTRYPNSNLLKSYFPDIRFNKNNTAQLVKWFSNFREFYYNQMEKFARQALAEGITDRNDIFVSKDSELFKVLNTHYNRNNHIKAPDRLVFVVQETLREFHDAIKQGKDIEPSWKKTIYKVINRLEDQIPDFFKEPNFLERLET
What is the function of this protein?
Transcription factor involved in developmental processes (By similarity).  Controls the transcription of genes required for excretory canal formation (PubMed:23334499).
What are the official names of this protein?
Homeobox protein prospero homolog 1, Homeobox protein ceh-26.
What is the protein family that this protein belongs to?
Belongs to the Prospero homeodomain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLNE_SHEON
Sequence: MAVQKDSNKSLSPLITQASERHWARLTEVWSEGLANLTAAQQQELKTVLGLSDYIANQLTRSPEWINALFADDLQQVERKLFDAQLREQLASATTEDMAKRLLRRFRNYQMVRFAWRDFLDYASLEESLLDLSALAEALVIGARDWLYKEMCVQYGTPMDKAGNPQPLLILGMGKLGGRELNFSSDIDLIFTFPEHGETVGGRRSLDNQQFFIRMGQRLVNLLDQITVDGFVFRVDMRLRPYGESGPLVVSFSGLEDYYQEQGRDWERYAMVKARSLGPWNHFSDELHSLLRPFVYRRYIDFSAIESLRKMKQLIAQEVRRRQLTDNIKLGAGGIREVEFVVQSFQLIRGGREPSLRQQSLFGAMDTLYSLGQFEYLAVDELKHSYLLLRRVENLLQAIDDKQTQTLPNNALDWARLCYVLDMTNEIDLRTHIEAAMAKIHRHFKATVGGEEGEEKAEHWTAQLWNVQQDDHAINLLAEQQIDDDKLWPLLSRWRETVTKRSIGPRGRETLDKLMPRLLDELLNQPSPSAAFEPVSKVLEQILTRTTYLELLCENPGARQQLVSLCCASPWIAVQLAKFPMLLDELIDPAHLYDTTSLDDYPSELRQYLLRVPEDDMEQQMEALRQFKLSQQLKIAAADVTGVLPVMQVSDHLTFLAEAIIEQVVMQAWQQVAVRHGVPSYLAESSDTGFAVIGYGKLGGIELGYGSDLDLVFLYEAPENMANSLTNGDRPIEVGHFYLKLAQRILHLFSTRTTSGELYEVDMRLRPSGASGLMVSEIARFGEYQAQEAWTWEHQALVRSRFVFGDNSLAVKFSQIRACVLEQSRDKDELKKAVREMRQKMRDHLLKVSEGEFDLKQSPGGITDIEFIAQYLVLANAHEYPELSIWSDNVRIFGVLAELELLPLMSAQHLTQSYCWLRDENHRLTLQQKSGKLAYADVAAHAERILAIYQAILE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: NUSB_NITWN
Sequence: MADIKASIDRKANRRGAARLAAVQALYQMEIGGAGINDVFAEFDSHWLGNEVEGDRYLPAEAAFFRDVVAGVVRDQVRIDPLIDDALSKSWPLKRVAAILRAVLRAGSYELEHRKDVPARVVVSEYVDVAHAFVEKDEAGMVNAVLDQIARRFRTGEFARG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PG044_VACCC
Sequence: MATKLDYEDAVFYFVDDDKICSRDSIIDLIDEYITWRNHVIVFNKDITSCGRLYKELMKFDDVAIRYYGIDKINEIVEAMSEGDHYINFTKVHDQESLFATIGICAKITEHWGYKKISESRFQSLGNITDLMTDDNINILILFLEKKLN
What is the function of this protein?
Virulence factor that affects the acute immune response to infection.  Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation.  Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.
What are the official names of this protein?
Protein K7.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG044 family.
Protein: EXGD_NEOFI
Sequence: MPSHSRSRDRYGGRDSDREARYDYDYARRRYATDDNDDDYDDDELEHGLNERRYRRDGYLPPRESRTRGYYERDAEGAADEELLGDERNPGPRASRSYGHDYDARRGERSRAREAPRRSERHRDRDREGQSRRRAYEDDGRHRTRDGRRERGRESDAEARRSRRREAGRETAARKHQSSDSTNSASHLLSADALARLGAQYEKEERRKRENAKDAAKAERKRQKKRAVVGEESRALRDPPGESHRDRTKARVASGAYLEEGRSPEMQVRHRGGGGPAMEARWRKEGSWGGTMDDAGGGRPFWKRKKWIGLGALILILVIVIPVAVVVSKKHDNKSDPADPQGTSPGKSNLDGLSHDSIPAYAQGTYLDPWTWYDTTDFNVTFTNETVGGLSIMGLNSTWDDSARPNDNVPPLNEPFPYGSQPIRGVNLGGWLSIEPFIVPSLFDSYSSVAGIIDEWTLSKRLGSSAARTLEKHYATFITEQDFADIRDAGLDHVRIQYSYWAVATYDDDPYVAKISWRYLLRAIEYCRKYGLRVKLDPHGIPGSQNGWNHSGREGVIGWLNGTDGELNRNRSLAVHDSVSKFFAQDRYKNIVTIYGLVNEPLMLSLSVEDVLDWTTEATKLVQKNGITAYVALHDGFLNLSKWKSMLKNRPDKMLLDTHQYTIFNTGQIGLNHTAKVNLICNDWYNMIKEINSTSTGWGPTICGEWSQADTDCAKYLNNVGRGTRWEGTFSLTDSTQYCPTADTGPPCSCANANADVSEYSADYKKFLQTYAEAQMSAFETGQGWFYWTWRTESAAQWSYRTAWKNGFMPAKAYAPSFKCGDAVPDFGNLPEYY
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Active on lichenan (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase D, Exo-1,3-beta-glucanase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: LCYE_ARATH
Sequence: MECVGARNFAAMAVSTFPSWSCRRKFPVVKRYSYRNIRFGLCSVRASGGGSSGSESCVAVREDFADEEDFVKAGGSEILFVQMQQNKDMDEQSKLVDKLPPISIGDGALDLVVIGCGPAGLALAAESAKLGLKVGLIGPDLPFTNNYGVWEDEFNDLGLQKCIEHVWRETIVYLDDDKPITIGRAYGRVSRRLLHEELLRRCVESGVSYLSSKVDSITEASDGLRLVACDDNNVIPCRLATVASGAASGKLLQYEVGGPRVCVQTAYGVEVEVENSPYDPDQMVFMDYRDYTNEKVRSLEAEYPTFLYAMPMTKSRLFFEETCLASKDVMPFDLLKTKLMLRLDTLGIRILKTYEEEWSYIPVGGSLPNTEQKNLAFGAAASMVHPATGYSVVRSLSEAPKYASVIAEILREETTKQINSNISRQAWDTLWPPERKRQRAFFLFGLALIVQFDTEGIRSFFRTFFRLPKWMWQGFLGSTLTSGDLVLFALYMFVISPNNLRKGLINHLISDPTGATMIKTYLKV
What is the function of this protein?
Involved in carotenoid biosynthesis.  Catalyzes the single epsilon-cyclization reaction which converts lycopene to delta-carotene and neurosporene to alpha-zeacarotene (PubMed:8837512, PubMed:11226339).  Required for lutein biosynthesis (PubMed:9789087).
What are the official names of this protein?
Lycopene epsilon cyclase, chloroplastic, Protein LUTEIN DEFICIENT 2.
What is the protein family that this protein belongs to?
Belongs to the lycopene cyclase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RS9_PSEPW
Sequence: MSATQNYGTGRRKTATARVFLRPGTGNISINNRPLDTFFGRETARMVVRQPLELTESTEKFDIYVTVAGGGVSGQAGAIRHGITRALMEYDETLRGALRRAGYVTRDAREVERKKVGLRKARKRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HIS5_THEMA
Sequence: MRIGIISVGPGNIMNLYRGVKRASENFEDVSIELVESPRNDLYDLLFIPGVGHFGEGMRRLRENDLIDFVRKHVEDERYVVGVCLGMQLLFEESEEAPGVKGLSLIEGNVVKLRSRRLPHMGWNEVIFKDTFPNGYYYFVHTYRAVCEEEHVLGTTEYDGEIFPSAVRKGRILGFQFHPEKSSKIGRKLLEKVIECSLSRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH, TmHisH.
What are the subcellular locations of this protein?
Cytoplasm.