PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_CLOB8
Sequence: MNIKTLTVSEVTNYIKRMLDNDFILSNLSVKGEISNLKYHSSGHIYFTLKDSSGRINCVMFKSNAVLLDFPLEEGMEVIIKGRASIYPATGSFQLYCDEIRKEGLGDLFIKFEKLKEKLSKEGYFDEAYKKELPKYPQRIGIVTSPTGAAIRDIINVSTRRSSLVDVVLYPAKVQGSGAYKDIISGINYFNRKKSVDIIIVGRGGGSIEELWNFNEEELAKAIFNSKIPIISAVGHEIDFTICDFVADVRAATPSQGAEIAVPLSDNIKDRLLDISKNLDKYISDRLDTCRNNLSGAQRILKVHSPMAKISNSYLEVDRLQDRLNFAMRTKIKGEKNKVENLNNLLFAHNPIKVISKGYAIIKDNENNIITSKEQLNEDKNIEVILKDGNIEGKFIPSK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX1_ASPNC
Sequence: MDDAEVDHTKPIPAYYCCYLLRSTKQRTSLYIGSTPHPARRLAQHNGESKGGARKTAKDDKRPWEMVLLVEGFTSRVGALQFEWAWQNPRMSSQHPANRHQFDLETGDVAGTSGVQPSTEAGKAKHRGRGSRRSLKAHLEDLHLFLRSTYFSKWPLRLRFFNRDVYQLWTTWCDRVDALLPEHVRTILDGDCPKDHLSWADEPRVGSVEHIKVDYSDIYDYVEKSHFLLDDPSDLRCKICQAKIALSEELALVCPRASCYCISHLLCLSSRFLDHAEEPEQLVPIDGICPLCNKVIQWSTMMQELSLRTRGHNEFRAILRKAKRGRAKAHGSVHEASAPDGVASAVENPGSRAACVESASVGVSDSLDVDNHDDASLDENWTESLDLDPNPDELLNRPKDHKMESSRVEIIIDDSDCEEMEDLG
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_SHEFN
Sequence: MHAIQTEMDQLTHTINQHNIRYYVDDAPSIPDAEYDRLIKRLTELEGDYPQFKSVDSPTQRVGGIALQKFAQITHLKPMLSLDNAFEQADFAAFNKRITDKVDNVDYVCEPKLDGLAVSITYRFGVLERAATRGDGSVGEDITANVRTIRSIPLKLRGEGFPDLVEVRGEVFMPKAAFEVLNQRQISKGDKVFVNPRNAAAGSLRQLDSKITASRALGFYAYALGVVEGESQPMQTSHYGQLTQLQQWGVPVSSEVKVTDSLEKVYAYYADIMARRSALEYEIDGVVIKVNDIAKQQTLGFVAKAPRWAIAYKFPAQEEMTLLESVDFQVGRTGAVTPVARLKPIFVGGVTVSNATLHNADEIARLGVKIGDTVIIRRAGDVIPQIVAIVPEKRPDDAQDIIFPQHCPVCQSIVERLEGEAVARCSGGLFCEAQRKEAIKHFASRKALNIDGMGDKIVEQLIDKELVKTPADLFSLTASSVTMLDRMAMKSATNIVAAIKQAKTTTLARFLYSLGIREVGEATAANLAQHFTEFERIRTASVEQLLEVADVGDIVAKHIRQFFSQPHNIEVIDQLLEAGITWPVIEQADESQLSLKGQTWVLTGTLTQLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGEAAGSKLAKAEELGVKVIDEQALMDLLNAAN
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DCUP_CUPNH
Sequence: MTALQNDTFLRALRRQPTEYTPLWLMRQAGRYLPEYNATRARAGSFLGLAKNPAYATEVTLQPLDRYPLDAAILFSDILTVPDAMGLGLSFAQGEGPRFAHPLRTEADVQKLAVPDMASLQYVFDAVSEIRRALVQDGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKAMMYGRPDLMHRILEINAQAVTEYLNAQIEAGAQAVMIFDTWGGALADGMYQAFSLAYMRRVLAGLKREHDGQQVPAIVFTKGGGLWLEALADTGADAIGLDWTVNLAEARRRTGGRVALQGNIDPTVLFAPEAAIREQVRGVLDSYAAAGGSDGHVFNLGHGISQFTPPDNVSVLVDEVHRHSRKLRAGQK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_NITMU
Sequence: MAEGKKYEIAVKVHTTYLPEQSDEALDRYVFAYTIVLSNTGTVTAQLISRHWVIADGSGGVQEVRGLGVVGEQPLLKPGDTYEYTSGTAISTPVGSMKGSYQMVAEDGLRFDAPIPEFILSVPRILH
What are the official names of this protein?
Protein ApaG.
Protein: USPB_ECOLI
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HTPX_BRUA4
Sequence: MNMTKTAMLIALMTVMFMSIGYLLGGGGGMMIALVIAVTMNLFGYWNSDKMVLRMYNAQEVDERSAPDYYRMVSGLAANAGLPMPKVYIIHEDQPNAFATGRNPENAAVAATTGLLNRLTPEEVAGVMAHELAHVQNRDTLTMTIVATLAGAISMLGNFAFFLGGNRENGNGIMGVVGTILAMIVAPFAAMIVQMAVSRTREYAADKRGAEICGNPLWLSSALGKIARGAKAIPNEEAEHNPATAHMFIINPLSGRGADNLFSTHPDTDNRIAALEQMAAEMGIRSAGMAPRAAAPSQSSGPWGNAGGNSNGGSGYRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURC_AGRFC
Sequence: MKMPKAIGLVHFIGIGGIGMSGIAEVLHNLGHRVQGSDQADSANVQRLRDKGIEVFVGHTADNLGDAEVVVVSTAIKKNNPELIAAREKHLPIVRRAEMLAELMRFRNAIAIGGTHGKTTTTSMVATLLEAGNLDPTVINGGIINAYGTNARMGEGEWMVVEADESDGTFLKLPADVAVITNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQALVGRIEDRKVITYGENPQADVRFSNVRIDGTRSIFDVEIRRRRTGKIFSFKDLVLPMPGRHNVSNATAAIAVANRLGISEADIKKGLASFAGVKRRFTLTGEANGVQVFDDYGHHPVEIKAVLAAAREACKGRIIAVHQPHRYSRLSSLFDDFAHCFNDADTILLAPVYAAGEDPIEGASSEALVSAIKAAGHRDARFLEKREDLASQVAAIANPGDFVVLLGAGNITQWAAALPSELKSISGKSE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB195_ARATH
Sequence: MSGMLGLSAVMGKRPKQQVTARPRKCPIEKPEEIPDDLLIDVFSRLSIEDVARCRCLSRFWSSILRRRYFTELFHKMSSTRPRILFTFLYYGKRLFYSMPQDLDPSNHYSPLPYFSISYSPISAHYQMHFPKVLGASAKVCPPILGLICCKSSKTMIFNPSTRESKFISTTKRVGVKSTSFGYDPIDKLFKVLSMSDDFVCRVSTLGTEVVTWRTVECSVPHHPLHSEICMDGVLYYLARRVGDETPKPYMVAAFEVRLERFKFLPMDLRCKHIGCSAVIDYKGKLAVVWLNVDRDNQRHIESFELRVLNDVDEVKWSQIIYELPNYWNNLPADIDVSIVGMTSAGEIVLATSHIRHPFYIFYYSTVTLAIVQLRIDFGIEAPEANHCSTMSTFVNHVENVELACGLGLSSIAM
What are the official names of this protein?
F-box protein At3g47030.
Protein: RS7_XENLA
Sequence: MFSTSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGAGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVYPSEIVGRRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVVFEFPEFQL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for rRNA maturation.
What are the official names of this protein?
40S ribosomal protein S7, 40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: ROCA_BACC2
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEELVGRVSKASRELAEKAMQVADETFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYGRQMLKLKDGIPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFVPGNGSEVGDYLVDHPRTRFVSFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEDVYDHVLNRAVELTKELTVANPAVLGTNMGPVNDQAAFDKVMSYVAIGKEEGRILAGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVITNNRDHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSETL
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: DEF4_ANDAU
Sequence: GFGCPFNQGACHRHCRSIRRRGGYCAGLFKQTCTCYR
What is the function of this protein?
Dual-function peptide with antimicrobial and potassium channel-blocking activities.  Shows inhibitory activity against Gram-positive bacteria.  Does not act on bacteria by disrupting membranes.  Also moderately inhibits Kv1. 1/KCNA1, Kv1. 2/KCNA2, and Kv1. 3/KCNA3 potassium channels.  Inhibits potassium channels by interacting with the pore region.  Does not show hemolytic activity.
What are the official names of this protein?
4 kDa defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_HAHCH
Sequence: MATINQLVRKPRSRKVAKSDVPALQGCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGYEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGTLDTAGVNDRRQGRSKYGAKRGKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TPIS_DICNV
Sequence: MRKPIAAANWKMNGDFSLLDDFAQANITSDKCETIFALPSVLLDRAQKLGLNALAGQDVSAQVKGAFTGEISASMLKMLGCQYCIIGHSERRQYHHEDEALLIEKWRRLKEAEITPIYCIGELQAEYDAHATQQALERQLRPILEENLVDHKTIIAYEPVWAIGTGKAATPDYAQHVHQMIRQIVAQNYASIAPAMRLLYGGSVKPDNAGLLICQADIDGFLIGGASLDVGLFTKIIETMK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_STAES
Sequence: MIEIEKPRIETIEVSEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKKLALKIYSEEDKTLEIDVKDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKVRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVSLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SYR_TROWT
Sequence: MNVEDLKKSVTNIVHSMYNFDCSEIVSLTRPPKPEYGDWALSLPLKLASLLKSPAIDIAQSIASALLELDGVQDVYVAKPGFINLKLSREHTTGIISEVLEQGSSFGRNTTQSSKKINLEFVSGNPTGPLHLAHTRWAAVGDSIARILINCGADVTREYYINNVGNQIHLFSESVYARALSKSLPKDGYPGEYVKDIARRIQCEFPNIIDLSYEDAIKIFRKRSWQIQIEEIKKSCIAFRVNFDVWFSEESLHEPDRFGKSQIDKALARCKQNGYLFQKNGAFFIRTTEFGDDKDRAVLRSDTSYTYYAADCAYYLNKINRGFSDLVILVGADHHGYVKRFQAMSNIFHVDSENNRKNVQVLLGQMVLLKNKRQSKREGNVIGLSEIIQSVGVDPLRFWFCRYPIDTPIDLDEQHLKKRSNDNPVYYVQYAYARTRSLIRSANLLQMEKFGFFPELLVHETETALVSLLYDYKTVVIDAARFLQPHRVVRYLESLAGAYHKWYDKCRIIPRKGILDKSEAELVNTRLELNRAVGQVLYNALDLIGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHYB_ORYSJ
Sequence: MASGSRATPTRSPSSARPAAPRHQHHHSQSSGGSTSRAGGGGGGGGGGGGGAAAAESVSKAVAQYTLDARLHAVFEQSGASGRSFDYTQSLRASPTPSSEQQIAAYLSRIQRGGHIQPFGCTLAVADDSSFRLLAYSENTADLLDLSPHHSVPSLDSSAVPPPVSLGADARLLFAPSSAVLLERAFAAREISLLNPLWIHSRVSSKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVRAISRLQALPGGDVKLLCDTVVEYVRELTGYDRVMVYRFHEDEHGEVVAESRRNNLEPYIGLHYPATDIPQASRFLFRQNRVRMIADCHAAPVRVIQDPALTQPLCLVGSTLRSPHGCHAQYMANMGSIASLVMAVIISSGGDDDHNISRGSIPSAMKLWGLVVCHHTSPRCIPFPLRYACEFLMQAFGLQLNMELQLAHQLSEKHILRTQTLLCDMLLRDSPTGIVTQSPSIMDLVKCDGAALYYHGKYYPLGVTPTEVQIKDIIEWLTMCHGDSTGLSTDSLADAGYPGAAALGDAVSGMAVAYITPSDYLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFKAFLEVVKSRSLPWENAEMDAIHSLQLILRDSFRDSAEGTSNSKAIVNGQVQLGELELRGIDELSSVAREMVRLIETATVPIFAVDTDGCINGWNAKVAELTGLSVEEAMGKSLVNDLIFKESEETVNKLLSRALRGDEDKNVEIKLKTFGPEQSKGPIFVIVNACSSRDYTKNIVGVCFVGQDVTGQKVVMDKFINIQGDYKAIVHNPNPLIPPIFASDENTCCSEWNTAMEKLTGWSRGEVVGKLLVGEVFGNCCRLKGPDALTKFMIVLHNAIGGQDCEKFPFSFFDKNGKYVQALLTANTRSRMDGEAIGAFCFLQIASPELQQAFEIQRHHEKKCYARMKELAYIYQEIKNPLNGIRFTNSLLEMTDLKDDQRQFLETSTACEKQMSKIVKDASLQSIEDGSLVLEKGEFSLGSVMNAVVSQVMIQLRERDLQLIRDIPDEIKEASAYGDQYRIQQVLCDFLLSMVRFAPAENGWVEIQVRPNIKQNSDGTDTMLFLFRFACPGEGLPPEIVQDMFSNSRWTTQEGIGLSICRKILKLMGGEVQYIRESERSFFHIVLELPQPQQAASRGTS
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome B.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: NRDR_BRUA4
Sequence: MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDNDRVERAISGIVRQLESSGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVAETEDDLDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PRD15_HUMAN
Sequence: MPRRRPPASGAAQFPERIATRSPDPIPLCTFQRQPRAAPVQPPCRLFFVTFAGCGHRWRSESKPGWISRSRSGIALRAARPPGSSPPRPAAPRPPPPGGVVAEAPGDVVIPRPRVQPMRVARGGPWTPNPAFREAESWSQIGNQRVSEQLLETSLGNEVSDTEPLSPASAGLRRNPALPPGPFAQNFSWGNQENLPPALGKIANGGGTGAGKAECGYETESHLLEPHEIPLNVNTHKFSDCEFPYEFCTVCFSPFKLLGMSGVEGVWNQHSRSASMHTFLNHSATGIREAGCRKDMPVSEMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSWPASGHVHTQAGQGMRGYEDRDRADPQQLPEAVPAGLVRRLSGQQLPCRSTLTWGRLCHLVAQGRSSLPPNLEIRRLEDGAEGVFAITQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQDTPRGEPPAVPESENVATKEQKKKPRRGRKPKVSKAEQPLVIVEDKEPTEQVAEIITEVPPDEPVSATPDERIMELVLGKLATTTTDTSSVPKFTHHQNNTITLKRSLILSSRHGIRRKLIKQLGEHKRVYQCNICSKIFQNSSNLSRHVRSHGDKLFKCEECAKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGTCEKTFRIESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTAAATQFTNLQPVAVGHLTTPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQLSDQHPLTWRAVPQTDVLPPSQPQAPPQQAAQPQVQAEQQQQQMYSY
What is the function of this protein?
Sequence-specific DNA-binding transcriptional regulator.  Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision.  Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs).  Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions.  Involved in early embryo development (By similarity).  Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming (PubMed:28740264).
What are the official names of this protein?
PR domain zinc finger protein 15, PR domain-containing protein 15, Zinc finger protein 298.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_SALNS
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: G6PI_BURMA
Sequence: MTLNSLPVWPALQAHYEEIRDAHLRDWFAPANDRAPTRAERFTFEGGGLAADFSKNRLTDATLALLVRLAREAGVEARRDAMFAGETVNPTEGRAALHTALRANAPDAPFQAQVAAERAKMARFADAVRSGAWTGYTGKRIRHVVNIGIGGSDLGPKMVVHALHHVATPDIATHFVSNVDGADLARVLERIDPEETLAIIVSKTFTTLETMTNARSLRDWFVANGCPEGALAKHFVGVSANPAEVVKFGIAEANVFEMWDWVGGRYSLWSAVGLSIMIAIGPERFDELLAGARDMDEHFRTAPLERNLPVLQGLVGIWYRNFFGAQSYLVAPYSEALHYLPSYLQQLEMESNGKSARIDGAFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTLVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLDEARKIAGPAKPELAPHLTFPGNRPTTTLLVDALTPRTLGALIALYEHKVLVQAAVWNINPFDQWGVELGKILGKVVEADLTAAQVDPAKHDSSTSALIARARKALGE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCTP_DROME
Sequence: MKIYKDIITGDEMFADTYKMKLVDDVIYEVYGKLITRQGDDIKLEGANASAEEADEGTDITSESGVDVVLNHRLTECFAFGDKKSYTLYLKDYMKKVLAKLEEKSPDQVDIFKTNMNKAMKDILGRFKELQFFTGESMDCDGMVALVEYREINGDSVPVLMFFKHGLEEEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO1_RHILE
Sequence: MPNSIWTSSDARAIHARMKKGDHLFLVDGSGFIFRAFHALPPLTRKTDGLPIGAVSGFCNMLWKLLRDARNTDVGVTPTHLAVIFDYSAKTFRKDLYDAYKANRSAPPEELIPQFGLIREATRAFNLPCIETEGFEADDIIATYARQAEATGADVTIVSSDKDLMQLVSPNVHMYDSMKDKQIGIPDVIEKWGVPPEKMIDLQAMTGDSVDNVPGIPGIGPKTAAQLLEEYGDLDTLLERATEIKQVKRRETILANIDMARLSRDLVRLRTDVPLDLDLDALVLEPQNGPKLIGFLKTMEFTTLTRRVAEACDCDASAIEPAIVRIEWGETARGPDLDAAEPEPVAGGIPEVSGESVPMPPRAKAKSAVEGAFSPADLAKARAEAFATLPFDHSAYVTIRDLVTLDRWIADARATGLVAFDTETTSLDAMQAELVGFSLAIADNTADPTGTKIRAAYVPLVHKNGVGDLLGGGLADNQIPMRDALPRLKALLEDESVLKVAQNLKYDYLLLKRYGIETRSFDDTMLISYVLDAGTGAHGMDPLSEKFLGHTPIPYKDVAGSGKANVTFDLVDIDRATHYAAEDADVTLRLWLVLKPRLAAAGLTSVYERLERPLLPVLARMEARGITVDRQILSRLSGELAQGAARLEDEIYVLAGERFNIGSPKQLGDILFGKMGLSGGSKTKTGQWSTSAQVLEDLAAAGFELPRKIVDWRQVTKLKSTYTDALPGYVHPETKRVHTSYSLASTTTGRLSSSEPNLQNIPVRTAEGRKIRTAFISTPGHKLISADYSQIELRVLAHVAEIPQLTKAFEDGVDIHAMTASEMFGVPVEGMPGEVRRRAKAINFGIIYGISAFGLANQLSIERSEAGDYIKKYFERFPGIRDYMESRKAMARDKGYVETIFGRRINYPEIRSSNPSVRAFNERAAINAPIQGSAADVIRRAMIKIEPALVEVGLADRVRMLLQVHDELIFEVEDQDVEKAMPVIVSVMENATMPALEMRVPLRVDARAATNWDEAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: YX13_CAEEL
Sequence: MASRSCICQVSAGIIFLIGAALLVAGLVIVLNVFPNIVNNQINDSKVLGLNADGTLNSFTDSWVNSKYISTMQYWVYDYTNTIGIMNRAIYPDVREKGPYAFDEILTMDKLNFSENGEFMEFRQIQTFVFNPNKSCAGCDPYKDKVLIPDMGFQVGIDQIDTVIEGILKNPLAATICHAIMKGKPNANQTCSNLGALIEGELGTLISLFNVSPFTTVTVDQLLFSGYKTPFVEKFLDEALGMLHFLFGTAPKPLDDPPIQLNPLNGTSDIINTVLTGKTDPLKAGYMTEFRSISNNSLFNSIGNTLPPMWWPYANKTYCKDPNSALVLTGTNGDYFKNFVKKTDILPAFVSDVCRTIHFVFDREVTVKGFKGYRFVMPPTQFDYSLDENCGYCIPLKYGSYEYPAQSACLPSGLLDISQCTGGPIIMSKPHFYQASKVVSKFVPRFKPTYDNDETMLDIEPNTGTVLQAQKRLQINMLVNQFKHIRSYSVMRPGAYPLAWVNESFYMDQNTIDQLNSQLFTPVSTVNTICWIAVGLGAGLIALSIVMVIVSFCCFRDEHHKTS
What are the official names of this protein?
Uncharacterized protein C03F11.3.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FIBG_BOVIN
Sequence: MSWSSHPPSVIFYILSLLSSACLAYVATRDNCCILDERFGSYCPTTCGIADFLNNYQTSVDKDLRTLEGILYQVENKTSEARELVKAIQISYNPDQPSKPNNIESATKNSKSMMEEIMKYETLISTHESTIRFLQEVYNSNSQKIVNLRDKVVQLEANCQEPCQDTVKIHDVTGRDCQDVANKGAKESGLYFIRPLKAKQFLVYCEIDGSGNGWTVFQKRLDGSLDFKKNWIQYKEGFGHLSPTGTGNTEFWLGNEKIHLISTQSSIPYVLRIQLEDWNGRTSTADYASFKVTGENDKYRLTYAYFIGGDAGDAFDGYDFGDDSSDKFFTSHNGMQFSTWDSDNDKYDGNCAEQVGIGWWMNKCHAGHLNGVYYQGGTYSKTSTPNGYDNGIIWATWKSRWYSMKKTTMKIIPLNRLAIGEGQQHQLGGAKQVGVEHHVEIEYD
What is the function of this protein?
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix.  Has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen gamma-B chain, Gamma'.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_THESQ
Sequence: MDHLVKIIEKKYEKKEIPDFRPGDTVRVHVKVIEGDRERTQVFEGIVIAKRGSGINKTFTVRRIGSHGVGVERIFPVHSPVVEKIEVVRKGKVRRAKLYYLRNVRGKIRIKERRD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.