PharMolix/UniProtQA huggingface dataset:
Protein: RECF_CLOB6
Sequence: MYIKNVHLINFRNYDDMYLELSPNTNIFVGNNAQGKTNILESIYYSSIGKSHRTNKDKDLIKWDKNNTYLRTYVSRERLDKTIDINIFKNGKKAITVNKIKIKKISELMGNLNVVMFSPEDLRIIKDSPGNRRKFLDIELCKINNVYYHDLVQYNKILSERNTALKNWNNKINDIIDIYDEQLSKYGAFIIKERNKYLDKLNIIGKNIHKKITNDLEDINFRYLTNIKDFDNAEKELLMFFKKNRKKDFERNSTSIGPHRDDFEVSINNIDTRIFGSQGQQRTAVLTLKFASLEIIKNIIGEYPVLLLDDVLSELDSNRQKFVLNSIDKIQTIITCTGIEEIDKYLDKKQSQLYLVNNGKIKRV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_LISMF
Sequence: MELVFLGTGAGVPSRGRNVTSIALSMLNERNTIWLFDCGEATQHQIMRSQIKLSKLEKIFITHMHGDHIFGLPGLLSSRSFQGGDSNLTIYGPAGIAEYVETSLRLSGTRLTYKINFEEIEPGLIFEDEMFLVTADDLDHGVRSFGYRIVEKDKQGALNAEKLKADGVEAGPVFQKLKNGEIVTLADGRVIDGKNYIGEPQKGKIISIFGDTKETANELELALNADILVHEATFEGDKAKMAGEYMHSTTLQAANLAKTANVKKLILTHISSRYDRDASKELLIEAKTIFENTEIAYDLAVFPIGE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: MURB_ANADF
Sequence: MAGALRGPGDADWRAEIERRVRGEVLRDAPLAPRTAVRVGGPADLLVRPADPGALAALLRAVRELSVPLTILGGGANTLVADAGVRGVVLRLPQGFGEEARDGERLVLGAGAPTSRLWVRAHAAGLVGIEFVAGIPGTLGGAVAMNAGTKIGEMKDVVSAVELATADGAGFVPAASLGFAYRTCRLPAGAVITRVQLTLRPGDVAESERIMQADRDGRRRTQPLDRPTFGSTFTNPPGDFAGRLVEAVGLKGHRVGGATWSDVHANFVSNLGGATARDVLALMRLARTRVKQRFGISLETEVRLVGEFHAEDLEGLRA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2240_MYCTO
Sequence: MLIGWRAVPRRHGGELPRRGALALGCIALLLMGIVGCTTVTDGTAMPDTNVAPAYRSSVSASVSASAATSSIRESQRQQSLTTKAIRTSCDALAATSKDAIDKVNAYVAAFNQGRNTGPTEGPAIDALNNSASTVSGSLSAALSAQLGDALNAYVDAARAVANAIGAHASTAEFNRRVDRLNDTKTKALTMCVAAF
What are the official names of this protein?
Uncharacterized protein MT2300.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YUAU_ECOLI
Sequence: MNADTWTRLQAFRHALELTSCEASLTAGYDHLKDFPAGCSELASQTLTDYLTEDGSNLYSCIVGMQWDNGPGRYGHVIAAPARDYIDLTLDQFPGYHNRIVAEPVESGGQLAADLNREPAISTADGIVASASDKVNYITEQKNRQPMVIITECYKLIRMTARFIPMCQSSQLFQHQIFPRLFIISDVGSCSLSRNTLDRLATDWKVTLSVLSL
What are the official names of this protein?
Uncharacterized protein YuaU.
Protein: HISZ_ACIBY
Sequence: MTISETWLLPDGVADVLPEQAQVIEKLRREAIDFLAVRGYQLVYTPFIEYIESLSSLSESNQDLDLVTFKVIDQLSGRLLGIRADMTPQVARIDAHVRPVEGVARYCYAGTVLHTKPQNFNATRAPLQLGAELYGHDSIEADVEMVDVMLGLIENAYTLQGAHLDLGHVGLFRSLVKYAGLSKNEEHELSDLYQRKALPELAEFTQNLNMGSDFYALGRYASDLDALQAHLSADILKDAEFDAALNALKTTLEQIKNRWPALNVGIDVVELRSYHYHTGLMYAVYAPNRAAPLAQGGRYDGIGEHFGRARPATGFSCDLYALGANQFAEIETVVAPKGTEADLLKAIANARSEGLRVVQLLGNDDLSSIPYATHQLVLQNGQWNIEKI
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_SHESH
Sequence: MTSENSIHNALYLGFNRSQWAELRESVPLTLNEPELADLRGINEKLSLTEVTDIYLPLSRLLNLIVGAKQKRGLVLNEFLGRKPPKRPYIISIAGSVAVGKSTTARILQALLSQWPEHPRVDLVTTDGFLYPLAELKRRGLLQRKGFPESYDMKMLVEFISNVKAGNEHVKSPLYSHISYDRIKSDYQAIEQPDILIIEGLNVLQSGQDSAVGIQQPFVSDFVDFSIYVDAEEQLLKKWYIDRFLQFRGGAFSDEKSYFHHYSNLADNEAKTIAANIWDSINGPNLKLNIEPTRDRAHLILQKGYDHLMSQVLLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_PELUB
Sequence: MEAFAAESGGMPQLNPEFWVSQIFWLIITFGILYVVLSKLILPKISANLENRKSQILENIEAAEKQREESEQKIEEYEKIVQSSKNEAKNYFKQAREKVLKDIGVKREILEKELDEEVNKAEIEIKTFRDNAPEKIKKIAVETSSDLLQELIGAEVNSSSISAIVEDLSRKKMDEYYGN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CHS4_MAGO7
Sequence: MSLPERPGAKASYEQRNSYRKSPSRRNRPNDIEASGYYPVTGGQHQRGPSVNSFAETIRSPNSNIESAPLSPSAEQIEHGSDQPFQRKRSLIRPERNRIDRDHPNYHYRKHAAKMNTLPSSTGNDPVLEDVSGATESGPPSGSNSASGSGVREENIPRKSRKASGRETVAEKSDNTRRRVSTRNSKIVKEGKRKEKIPEQLRPPSAWNVYCAVITFWSPDFIMKCCGMPAKAQRRAWREKIGLISLILIIMGVVGFLTFGFNQAVCGGPVLRLHINSVDRSYMIFHGTAYNLDGSHHPVAEGIPKRLDGTGANVVYDLPEGYGGTDGSFMFQNVNGKCKGLITKAPNSDVPSEGDNLAWYFPCHARNQDGSSQPNMTYPYYFGYACHTTPLARSTFYTQLDKSADVYFTWADIRNNSRNLFVYSGNVLDLDLLFWFNRDQVNIPRRFEELRDKNNAANRAIRGRDATRTFMASGDRQIAECFEDIIKVGTVDTDTVGCIAAKVVLYVSLALILSVVGARFTLALIFQWFISKNYAADKTSQTSDKRKRNKQIEDWSEDIYRAPPRMPGDVGSSVAGASSSDHTSKRSSFLPTTSRFSTVYGAERSARNKSMPTTMASQASGGYMGPSSTAYRETNESRTSFLKSDPYATNTAPIEGPGPSGFIHDSVVPQPPSDWMPFGFPLAHTICLVTAYSEGELGLRTTLDSVAMTDYPNSHKVILVICDGIIKGKGESKSTPEYVLDMMKDHTIPVEDVEAFSYVAVASGSKRHNMAKIYAGFYDYGTQSNIPLDKQQRVPMMVVVKCGTPDEMVKSKPGNRGKRDSQIILMSFLQKVMFDERMTELEYEMFNGLWKVTGISPDFYEIVLMVDADTKVFPDSLTHMISAMVKDPEIMGLCGETKIANKRDSWVSAIQVFEYFISHHLAKSFESVFGGVTCLPGCFCMYRIKAPKGAQNYWVPILANPDVVEHYSENVVDTLHKKNLLLLGEDRYLTTLMLRTFPKRKQVFVPQAVCKTTVPDSFMVLLSQRRRWINSTIHNLMELVLVRDLCGTFCFSMQFVIFIELIGTLVLPAAIAFTFYVVIISIINQPPQIIPLVLLGLILGLPAILIIITAHSWSYVLWMLIYLLSLPVWNFVLPAYAFWKFDDFSWGDTRKTAGEKTKKAGIEYEGEFDSSKITMKRWAEFERDRRARQSQYWGSRENVTGGVRTASGVWASAPPHHHQQQYDEYYSDA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 4, Chitin-UDP acetyl-glucosaminyl transferase 4, Class-IV chitin synthase 4.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS19_LACPL
Sequence: MGRSLKKGPFADAHLLKKIDAQSDSDKKSVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQDDMVGHKLGEFVPTRTFHGHGTDDKKTK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CLPX_VIBA3
Sequence: MTDKSKEGGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESESLPTPREIREHLDDYVIGQEYAKKVLAVAVYNHYKRLRNGDTTAEGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKAENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRVETGSGIGFGAEVRSKDETKTIGELFTQVEPEDLVKYGLIPEFIGRLPVTTTLTELDEEALIQILCEPKNALTKQYAALFELEDTELEFREDALRAIAKKAMNRKTGARGLRSILEGVLLETMYELPSSTDVSKVVIDESVINGESEPLLIYSNSDNQAAVAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CYSP_BLOTA
Sequence: MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHNGIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDSSYQCNGCGSGYSTEAFKYMIRTGLVEEENYPYNMRTQWCNPDVEGQRYHVSGYQQLRYQSSDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNGGYGYVERGHNSLGINNFVTYATL
What is the function of this protein?
Cysteine protease.
What are the official names of this protein?
Cysteine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: RL2_GEOUR
Sequence: MAIKSYKPTSAGRRHQTCSTFEEITTDKPEKSLLVKLKKTGGRNNFGRVTSRHIGGGHKQKYRIIDFRRDKRDIPAKVSSVEYDPYRSARIALLNYADGEKRYIIAPLDLKVGDTVISGPSADIKPGNALPIRSIPLGTIIHNIELKIGKGAQLARSAGTFAQLMAKEDKYAQVKLPSGEVRMVLLDCIATVGQVGNIDHENVSIGKAGRSRWLGKRPKVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRTNKTSTRFIVKRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NDHJ_ZYGCR
Sequence: MTNLAFQSSSQIQGRLSAWLVTHKLPHRPLGFDYQGVETIEVRPEDWPSVAVALYVYGFNYLRCQCAYDVAPGGALASVYHLTKVEDVADQPEELCVKLFVSRNNPSVPSSFWIWKSADFQERECYDMFGIVYKNHPHLKRILMPESWLGWPLRKDYITPDFYELQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL11_LACLM
Sequence: MAKQVEKLVKLQIPAGKATPAPPVGPALGQAGVNIMGFTKEFNARTADQAGMIIPVVISVYDDKSFTFITKTPPAAVLLKKAAGVQKGSGEPNKTKVASVTKAQIKEIAELKMPDLNAASVETAMSMIEGTAKSMGFTVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CC42M_XENTR
Sequence: MEFDLGEYFRAAFEDKLLVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQMRLKTEISVEDTEAQLEKIQICFEDLSAIYKDLKKAGTTPQTPAVPTTN
What are the official names of this protein?
Coiled-coil domain-containing protein 42 like-2.
What is the protein family that this protein belongs to?
Belongs to the CFAP73 family.
Protein: PURQ_GEOSW
Sequence: MKFAVIVFPGSNCDVDMYHAIADELGEEVEYVWHDAENLDRFDAILLPGGFSYGDYLRSGAIARFSNVMKAVKKAADEGKPVLGVCNGFQILLEAGLLPGAMRRNNSLKFICRPVSLRVENNETMFTSAYKQGEVITIPIAHGEGNYYCDEQTLKRLIENRQIVFRYHGENPNGSLDDIAGIVNEKGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKYWRETHVVTA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_USTMA
Sequence: MNTITLFFLFIPILAVILLFANLLLAVHRPDSEKVTPYECGFSPVYGQTRNPFSIQFYLVGILFLVFDIEILLTYPYAMNLYQTSTYGFWIFVIFFLVLTVGFVYEFGTGALYFTDKRSSIQNTKISDSKHSPFFWSKSEKRL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL14_DESAH
Sequence: MIQTETRLTVADNSGAKELYCIKVLGGSKRRYAGIGDVIVVSVKEAIPNAKVKKGDVVKAVIVRTKKEVSRPDGSMIRFDDNSAVIINASNEPIGTRIFGPVARELRAKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TIM9_CAEBR
Sequence: MASEQNIQTFRDFLTQYNLVAEQCFTSCVNEFGSRTVNAKEESCANNCLDKFLKMTQRVSQRFQEHQILNAQANGAAM
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: LUXS_PSYIN
Sequence: MPLLDSFTVDHTIMNAPAVRIAKTMQTPSKDTITVFDLRFTVPNEDLLSEKGIHTLEHLYAGFMRNHLNSPDVEIIDISPMGCRTGFYMSLIGSPSETEVANAWLAAMRDVLAVEHQEEIPELNKYQCGTYAMHSLAEAKTIAQAVIDAGVGTNKNADITLSDEQLKQL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: OPHN1_PANTR
Sequence: MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTMTPMEQKPGAKQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLWMEAMDGKEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEESAAPPVPPPRVTARRHKPITISKRLLRERTVFYTSSLDESEDEIQHQTPNGTITSSIEPPKPPQHPKLPIQRSGETDPGRKSPSRPISDGKLEPCPEVDVGKLVSRLQDGGTKITPKATNGPMPGSGPTKTPSFHIKRPAPRPLAHHKEGDADSFSKVRPPGEKPTIIRPPVRPPDPPCRAATPQKPEPKPDIVAGNAGEITSSVVASRTRFFETASRKTGSSQGRLPGDES
What is the function of this protein?
Stimulates GTP hydrolysis of members of the Rho family.  Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function.  Critical for the stabilization of AMPA receptors at postsynaptic sites.  Critical for the regulation of synaptic vesicle endocytosis at pre-synaptic terminals.  Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).
What are the official names of this protein?
Oligophrenin-1.
What are the subcellular locations of this protein?
Postsynapse. Presynapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cytoplasm.
Protein: DFA11_MOUSE
Sequence: ALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLLYMLCCR
What is the function of this protein?
Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
What are the official names of this protein?
Alpha-defensin 11, Defensin-related cryptdin-11.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPG_ECO57
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RIBD_CHLTR
Sequence: MEVLSEQQLFFMRKAVALGEKGRIFAPPNPWVGCVIVKNGCVIGEGWHQGIGSPHAEVCAVQDQKCSLEGAEVFVTLEPCCHFGRTPPCVDLLIKSKVAAVYVGLLDPDPRVCKKGVARLQAAGIPVYVGVGSQEAKTSLQPYLYQRERGLPWVVMKTAASLDGQTADRGGSSQWISGELARADVGKLRAESQAIIVGARTVCLDNPRLSARFPHGDLYERQPLRVVVDSRGTVPLESRVFDLSSGSTLFATTQQCPKEYIQKLKDLGVEVWESSSHQVDLKGLLRYLAERGCLQVLVEGGAQLHSAFWQQKLVNAGVIYWGPKFLGDQGQPMLRDLQLSLVTAEHVRITETSLVRDSVKTCFECLEQESVDKKG
What is the function of this protein?
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HTP reductase family.
Protein: CMOA_ACTP7
Sequence: MNKDTIFSAPIEKLGDFTFDESVAEVFPDMIQRSVPGYSNIITAIGMLAQRFVTEGSQVYDLGCSRGAGILSIRRNLQTNQVKIIGVDNSQPMVERCRSHINAYHSDVPVEILCDDIRHIEIKNASMVVLNFTLQFLPRADRLELLTKIYQGLNPNGILVLSEKFTFTNQAMSELLIDLHHTFKRANGYSELEVSQKRTALENVMLTDSIETHKDRLKQAGFSQIELWFQCFNFGSMIAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: IGDB2_CAEEL
Sequence: MMRWRLAVLFLTLLASTTGDDTTTKASVSTTTKKGTDGPHLTTDDEGFLTVIQGFATQLQCVLNTCSKDVIWYKDGSQISKGSQFLNTTSEKAYKIQHSIEVDYEKGCSGECDDSKPCGDGFSCVDNQCCSCRREEFTLVLRNLTFDESGRYRCQLGNKSELLEFQVEVLESGLKGGFHENISYDHSECCQEKGISPLCRGMCKPSEMDQHHFDPTSCKTDDYKHFLSCATEDGTRSHVHCCKTQLVPSFCYDFCSGDFQMLRRSHRLCLYYLPEIFSCLDRAYLPYPDPPTAIEVNAVEHDKLSVCWKEPEKHESNKMFPILDYAVYFKEIPNFPLLGGDMGLPLLTGDYSDIGDIQEDDYQQEEDDAEEVVKDSTIAPRGKRDVDFESDGVKVQIREKRSTMVIVTRDDVTNSTTIREFAFQNVNTTERCVTLSDLRSSTRYIVYVTARNEYGTSVPSVRNIASTNVHMVKNNASLPDSMKCCTDANVTSFCSSKMCNVAEDPSSFSTITIATTCRAEWPKVSPCIADGRNHTDCCLKKGVQHDCLEICSGSTKELGVHSVLCLNLDLQAIYQCIRQGYETHPSAPGNVTISELTAHSVTVQWTEPNSNAHLVENYTLFIRKNEHGEAVRTVKNVISPHVELGLDPDSEYVLTLQSHSANGTSLPSTAKLFSTLPTTRPPLCTIGEPIYMNDGRVMICDAVNPCPNGFRCTGAGSDLSYCCPHDGTHSSEEFTSCCKEQKMPESCMSSCQYNMTLPESCKENLNTWVQCASEGHDHLRCCLQEEVSKPCQTACMHPFTVPADECFSEVSKYRTCFSAAHQALPAAVRNVEVSSISKDSATISWEDLEANIIVFRVQLFEKGGNLIKTENSSADIFRFIDLEPNKDYSVRVTAINFLGEGPPSWNATFTTKPAQIYEGDRPVAPEKLRISWNSGPRVNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQSSTWTTLRTNQTWVVMRDLRKDALYYVYVTAKEDNRTSRSSSIITILAQKDSPGLPEPTIVIEPDHKDGVFSPGEKISINCSLPNIKKHLNIDLTVGSHVVQNDHGALWVILETEADEAMDTATCAVSDTDGRQHVAMKHLVLERKASVTMKKDKIRVLDDQSVEIECIYRGGGLDPKISFEKDGKKASRGFLNLKKTEAGYVAKWHIRKVKQEDAGFYKCVVTSSDGSRVEASSEVIFSTETLPVNPKLILQCCEDEGITGDCLQACNIGRTSLSIKNQNCTRFAVSLLKCASDIRDHSDCCIASGVTSKCLPLCSGDSFSPDIDCSEHAVSIMTCSVKSHEHAPSEVSNVRIKASEGKVNIEWDYPLTKDYKYFAVYYRKAHDDHEDWHKLKTIQQNIELDVDPSEDYEVGILAANALGHSRLMYSAIPKDSEPRRSASKGSSSAFWIVVILVVFGVLIAGLAVLSKRRELPYPIGKFIGRRNDPNQPTVAFENPAYGEPWGGAEVEIRGLGGSATTGTAAATQSEWQSANLEANSTTDNSHEYRNGMRYAKLET
What are the official names of this protein?
Ig-like and fibronectin type-III domain-containing protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GCSPB_STAS1
Sequence: MVVSKSSPLIFERSKKGRYAYSLPKKEIDNGAVEKLLDDKFIRKNKAELPEVAELDLVRHYTELSNKNFGVDSGFYPLGSCTMKYNPKINEKIARIPGFAESHPLQDESQVQGSLEIIHSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAFHQKNGEGHRDEVIVPDSAHGTNPASAAFAGFKAVTVKSNERGEVDIDDLKRVVNENTAAIMLTNPNTLGIFEKNIMDIRNIVHEAGGLLYYDGANLNAIMDKVRPGDMGFDAVHLNLHKTFTGPHGGGGPGSGPVGVKKELASFLPKPMVVKEDDVYKYDNDIENSIGRVKPFYGNFGIYLRAYTYIRTMGNKGLEEVSEAAVLNANYIKARLKDHFEIPYPQYCKHEFVLSGSKQKEHGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFCDKMIEIANEAKEDPDKVLEAPHTTIIDRLDETKAARQPVLKFENLRSEKE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.