PharMolix/UniProtQA huggingface dataset:
Protein: NUOK_HERA2
Sequence: MISTNAYVLLSAILFTIGVVGVLVRRNVIVMFMSVELMLNSANLALIAFSRARAESDGQIITFFVIAVAAAEVAVGLALLVSIFRAKKTTNIDDVNTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RGS17_MOUSE
Sequence: MRKRQQSQNEGTQAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGDSSGRSPHTTKMESIQVLEECQNPTADEVLSWSQNFDKMMKTPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKAVEEKARMIYEDYISILSPKEVSLDSRVREVINRSLLDPSPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKAFVESTTSCTSES
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity).  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.  Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities.  Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.
What are the official names of this protein?
Regulator of G-protein signaling 17, RGS17, Regulator of Gz-selective protein signaling 2.
What are the subcellular locations of this protein?
Membrane. Synapse, synaptosome. Nucleus. Cytoplasm.
Protein: RHES_HUMAN
Sequence: MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ
What is the function of this protein?
GTPase signaling protein that binds to and hydrolyzes GTP.  Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3.  May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
What are the official names of this protein?
GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RasD family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PO152_YEAST
Sequence: MEHRYNVFNDTPRGNHWMGSSVSGSPRPSYSSRPNVNTTRRFQYSDDEPAEKIRPLRSRSFKSTESNISDEKSRISERDSKDRYINGDKKVDIYSLPLISTDVLEISKQRTFAVILFLIIQCYKIYDLVILKSGLPLSGLLFKNYRFNFISKYFIIDSFFLYVLPSFNIPRLTFKPWVVYLQILAMLLLNIFISSDHEFVLISLIMTTWRKLYTKELSVTGSAINHHRIFDSSAHFKGALTIKILPENTAMFNPLHESYCLPMDTNLFKINSIDVPIRINSTEEIEYIELEYRDLYTNSVELRSLSKKDFKIIDNPKSFLKKDQSVLKSHSNDFEEGSTIRYLAVTLQDIGFYQIKKIVDSKKLNLKIHQSHLVVPYCPIASITGTGSNDRCIGDSDNVSFEIQGVPPMKLAYSKIVNGQTFSYVDSSLQPEYFESPLQSSKSKQSFTQGELNDLKWGRNQPVNINLDSSITQDGKFAYKIDKITDGLGNVVDFTSLPEELKKRYDLSYNFNVHEVPRAALEERFDPKSPTKRSIAIVFEEIKNWISDIPYVISLSYTDAQDKSKKIMNVTTDSLTKVLQADLPGSYNLEYIESKFCPGEIVGKSNVLVTMPVAPTMEVKSFPILDQCVGQVGLNFELSFTGAPPYYYNTKIYKLENGERKLYDAKRYTSEGTRNRFSYSPPKEGNYEIVFDTVSNKLFTEPIKLEPVKEYTFKTSMRVKPSASLKLHHDLKLCLGDHSSVPVALKGQGPFTLTYDIIETFSSKRKTFEIKEIKTNEYVIKTPVFTTGGDYILSLVSIKDSTGCVVGLSQPDAKIQVRRDIPSAAFNFFEPIKEAKIKHGSVTEIPLKLSGEGPFTVKFKHMDYDGNIVKEFENKFQNSYKPALKVSKEGLYQLVDIRDSSCQGNVIYRNSLYKVSFLEKPKFAIQDNHHITKVTENLFSKEEVCQGMEGTVDLALFGSPPFILEYDLMAPNGHISTKKIQVATKYASLKLPNQIPGEYITTIKAIFDGNYGESDIHFREHQSELIIKQTVHPIPDVAFADGGKTLRACAANVDQISFLEPINLKFLQGESPFSITFSVYHESTSRTDQYTIDNIDSENFSFEKLYEGMKLGNHAITIDSVVDANGCVNSLISGPRNQILVSITDAPKIHILDPSTEYCVGDYVAYQLNGVAPFMIKYEFNGIPLKSKERSSQFVRLASEPGIISITSLQDSSSQCIVDFTNPKLKSEFDDLSLNIHPIPSVTVSQGNYVTEDIREGDQAEVIFSFEGTPPFSLTYVRTEETDGKHGKRRSQVVETHKVTDIYSHEYKVITSLQGTYEAIEITDAYCFAKNDLFFNN
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  POM152 is important for the de novo assembly of NPCs.
What are the official names of this protein?
Nucleoporin POM152, Nuclear pore protein POM152, P150, Pore membrane protein POM152.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
Protein: HSLU_BURM7
Sequence: MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVAEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTRETEMRKVRSKATDLAEDRILDVLLPQPRAVGFGASAEHANDDNNATRQTFRKRLREGQLDDKEIELDIEQPAVGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIREALKLLTDEEAAKMLNDEEVKTKAVQNVEQNGIVFLDEIDKITSRNHEGGGGEVSRQGVQRDLLPLVEGTTINTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVKDFEAILVATDASLVKQYQALLATEDVKLEFADDGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFAAGNHAGQSVTIDSAYVDRALGEVSKDEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10E_NATPD
Sequence: MSDKPASMYRDIDKPAYTRREYITGIPGSKVAQYKMGNFEADPEDYEVQISLIVDEEVQIRHGSLEASRLSANRRMLKELGEDGDYKMILRKFPHQVIRENKQATGAGADRVSDGMRQAFGKIVGTAARINKGERVFTIWCHPEDADAAKDAFRRAYNKISPPCTIKVERGEELLIA
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NR1H3_HUMAN
Sequence: MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
What is the function of this protein?
Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920).  Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity).  LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity).  Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530).  Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).  Induces LPCAT3-dependent phospholipid remodeling in endoplasmic reticulum (ER) membranes of hepatocytes, driving SREBF1 processing and lipogenesis (By similarity).  Via LPCAT3, triggers the incorporation of arachidonate into phosphatidylcholines of ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL) particles.  Via LPCAT3 also counteracts lipid-induced ER stress response and inflammation, likely by modulating SRC kinase membrane compartmentalization and limiting the synthesis of lipid inflammatory mediators (By similarity).
What are the official names of this protein?
Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear receptor subfamily 1 group H member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: YCIB_NITHX
Sequence: MDKKQPHPLFKLATELGPLLVFFAANAKFNLFVATAAFMVAIVAAMIASYVVTRHIPLMALVTGIVVIVFGTLTLVLHDETFIKVKPTIIYSLFAGVLGGGLLFGRSFIAIMFDQVFNLTPRGWQVLTLRWALFFFGMAILNELIWRTQSTDFWVNFKVFGAVPLTMIFAMMQMPLTKRYHLEPATLEASDASEGDVRK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABH_STRPJ
Sequence: MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRHISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVFDFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMMEYGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_SODGM
Sequence: MALSRLMIRDFRNISVADLSLAADFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQSGRVIRHEQPEFVLHGRIEAGNVDARATSVGLSRNRLGDSTVRIDGSDGHKVAELAQLLPMQLITPEGFTLLNGGPKYRRAFMDWGCFHNEPAFFTAWSNLRRLLKQRNAALRQVSRYQQLRVWDQELIPLANRISEWRADYSAAIAADITATCAQFLPEFRLDFSFQRGWDKESDFGELLERQFERDRALTYTASGPHKADFRIRAEGVPVEDILSRGQLKLLMCALRLAQGEFLTHRNGRRCLYLIDDFASELDTGRRRLLAERLKATHAQVFVSAVSADQIRDIPDEKGKMFKVEQGKISLQSEV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_ECOSM
Sequence: MKPDAHQVKQFLLNLQDTICQQLSAVDGAEFVEDSWLREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEVMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCQPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTNAYLPIVERRKTMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALNEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOSC_BACSU
Sequence: MISRASAVYDKLKQAERNIRGDESMQTLDAPIYEVKQESDWYKSEKKRKEDINSFFDKFEEKYGVKEGFSFYHSEYFGVYEGTEAYEIFKNDIVKNQVDGFYAFKKRSKYFKEIKAMIEQIEEVYPFRSHDELGLNNMTGRQWIGDRWFFGVKTEQLVNGDSVVATDYKDYLKIVMEHLD
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YosC.
Protein: BDS5_ANEVI
Sequence: MNKALFLCLVVLCAAVVFAAEDLQKAKHAPFKRAAPCFCSGKPGRGDLWIFRGTCPGGYGYTSNCYKWPNICCYPH
What is the function of this protein?
Is member of a fraction that shows antiangiogenic activity, since it inhibits human microvascular endothelial cells (HMEC) tubulogenesis (PubMed:29671760).  This protein could be a kunitz-type inhibitor with a RGD motif that could block angiogenesis in binding on integrins (Probable).  Blocks Kv3 voltage-gated potassium channels (By similarity).  Reduces blood pressure (By similarity).
What are the official names of this protein?
Kappa-actitoxin-Avd4e, Kappa-AITX-Avd4e, Antihypertensive protein BDS-5, Blood depressing substance 5, BDS-5.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: GLO2_LEGPA
Sequence: MTILPISAFSDNYIWTFIDKIAGVLDCVDPGEAGPIIRFAQSNQLTLRTILLTHHHYDHIGGVDLLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYYEPQQGWLFCGDTLFSAGCGRVFDGTIEELHESLLLFKKLPRNTKVFCAHEYTLQNLKFAHTVEPCNSSVINYMQQILKQPSPCTLPSNIDLELSINPFLRTDKEQVKQYALSHGANSSDSLDVFKVLRNQKNSFK
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: LOLD_BDEBA
Sequence: MRAVDIHKSYSQGVGELEILRGVSLDIREGEAFAILGASGAGKSTLLQIMGTLDRPNKGELYCEGRDLLAMSDDELSRFRNSEMGFVFQFHHLLSEFNALENVMIPCRVGGESIKVAKEKALHLLEFMGLADRRDHHPNQLSGGELQRVAIARALVRHPKILFADEPTGNLDSHTSGKIQELFFRLKEEMKLALVIVTHDLTFATRFPKVYRMKDGQWQS
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TY33_PHAJA
Sequence: QDKPFWDPPIYPV
What are the official names of this protein?
Tryptophyllin-T3-3, Pj-T3-3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPC_PAEAT
Sequence: MTVLDDIIVGVKEDMEVRRGLVSLAELKERAANAAPARDAWAALGGPSSIRNDLKVIAEIKRRSPSKGDLASIADPASLAVQYADGGASVISVLTEQRRFGGSLADFDAVRAAVETPLLRKDFTVDEYQIWEARAHGADLILLIVAALSDAELADFSALSHELGMNVLVETHTEEEIERAVAAQAKIIGINVRNLKTLDVDRSVFGSLAGLIPAESVIVAESGVRGPEDVSHYAAGGANAILVGEALVSDSTPRERITEFKAAGAAAIAVRN
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: KUP_HERAR
Sequence: MASPDKKSSLAALTLAAVGIVYGDIGTSPLYTMKEVFSKEHGLDLTPENLLGVVSLIVWGLIIIVSLKYVTLVLRANNRGEGGIMALMALALSSVTKNSRWYFPLMVMGLFGATLFYGDSVITPAISVLSAVEGLGVATSAFDPYVVPVTVAILVGLYSLQARGTAGIGKWFGPVMLIWFITLAVMGVVNIIDAPYILHALNPWHALHFLSGNGFLAFIALGAVVLAFTGAEALYADMGHFGAKPIRMAWFLIAFPALSLNYLGQGALLLLNPEAVTNPFYQQLGAWSIYPLVALSTMAAIIASQATISGTFSMTKQAIALGFLPRMKIEFTSASQIGQIYIPAVNWLQMIVVVLAVIGFGSSSNLAAAYGIAVTATMMVTTVLTFFVIRYRWKYNLILCVAATGFFLVIDLSLFSANMLKLFHGGWFPLLLGVVLFTLMLTWKRGRELVFENLQKHAIPLEDFLASLFISPPTRVPGTAIFLRGESDGVPHAMLHNLSHNKVLHERVVFLTVRMMEVPYVPKADQVRIEHLGDDCYQMNVTYGFKNVPDIPAALDLAKEQGLEFEMMETSFFIARQTVVANPVRGMALWREHIFVAMSRHARGAADYYQIPSNRVIELGTKVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTNC_XANP2
Sequence: MTIKAILTDIEGAAGPASFLKDILLPYAREHLGAFIAAHAEDDGIEEALEEAGRLMGGFSLKPDEAEALLQRWMKQGRNPTPLKIIQGRIWQQGYEAGAFTAEIFPDVAPSLGAWKNAGIRLFTYSSSSELAQRLWLGSAGAEVFEGFFDTRVGQKLEEESYKAIAEQLALPAAEILVLSGNEDELDAAKAAGLATALIAREGGGGGNHPVAADFASVTIG
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: HOX27_ORYSI
Sequence: MELGLSLGDAVTVADGGRLELVLGLGVGVGAGVRRGEEEERGRREDVVGAGRWAAMAAASPEPSVRLSLVSSLGLHWPSETGRSEAAARGFDVNRAPSVAAGAPGMEDDEEGPGAAPALSSSPNDSGGSFPLDLSGHGLRGHAEAAAQGGGGGGGGERSSSRASDDDEGASARKKLRLSKEQSAFLEESFKEHSTLNPKQKVALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCETLTEENRRLHKELAELRALKTARPFYMHLPATTLSMCPSCERVASNPATASTSAPAAATSPAAAPTAAARTAVASPEPHRPSSFAALFAAPLGFPLTAAQPRPPPPASNCL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX27, HD-ZIP protein HOX27, Homeodomain transcription factor HOX27, OsHox27.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPSA_PYRHO
Sequence: MDKMAYKFIKWFEELRKDDVPLVGGKGANLGEMTNAGIPVPPGFCVTAEAYKYFVENVKVSKEDVKKILGEKANKGTIAEVLASAPDEPRTLQEWIMDIINRTNVDDSKQLQENTAIIRELIESLEMPNEIADEIKQAYKELSQRFGKDEIYVAVRSSATAEDLPEASFAGQQETYLDVLGADDVIDKVKKCWASLWTARATFYRAKQGFDHSKVYLSAVVQKMVNSEKSGVMFTANPVTNNRNEIMINASWGLGEAVVSGAVTPDEYIVEKGTWKIKEKVIAKKEVMVIRNPETGKGTVQVKVAEYLGPEWVEKQVLTDEQIIEVAKMGQKIEEHYGWPQDIEWAYDKDDGKLYIVQSRPITTLKETTTEEVEEVEEAEVILKGLGASPGIGAGRVVVIFDASEIDKVKEGDVLVTTMTNPDMVPAMKRASAIITDEGGRTSHAAIVSRELGIPAVVGTKEATKKLKTGDYVTVDGTRGLVYKGIVKSLVEKKKKEEAAAAPGAAVAAAPLVTGTLVKVNVSMPEVAERAAATGADGVGLLRAEHMILSIGQHPVKFIKEGKEDELVERLAEGIEKVAAAFYPRPVWYRTLDAPTNEFREMPGGEDEPEERNPMLGWRGIRRGLDQPELLRAEFKAIKKVVEKGYNNIGVMLPLVSHPEQIRKAKEIAREVGLEPHKDVAWGIMIEVPAAAIIIEDLIKEGIDFVSFGTNDLTQYTLAIDRDNERVAKLYDETHPAVLKLIKHVIKVCKKYGVETSICGQAGSDPKMARILVRLGIDSISANPDAVQLIRQVVAQEERKLMLEAARKKLLEEEEEEEDLF
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Probable phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: SECY_STRSC
Sequence: MLTAFARAFKTPDLRKKLLFTLGIIVIYRIGTHIPIPGVDYSAVQFCIDQTKSNSGLFGLVNMFSGGALLQITIFALGIMPYITASIILQLLTVVIPRLEALKKEGQSGTAKITQYTRYLTVALAVLQGTGLVATARSGALFSQCPQANNIVPDDSIFTTLTMVVTMTAGTAVVMWLGELITDRGIGNGMSILMFISIAATFPSALWSIKEQGDLAGGWIEFGIVIAVGLVMVALVVFVEQAQRRIPVQYAKRMIGRRSYGGTSTYIPLKVNQAGIIPVIFASSLLYIPALVVQFSGSTAGWAAWIQKNLADTAAPAHITVYFFLIIFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNRITWPGSLYLGLIALVPTMALAPLGANQNFPFGGTSILIIVGVGLETVKQIESQLQQRNYEGFLR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYAY_RALPJ
Sequence: MPPLSESEFLALAEAELTRIENIVETAADEADADIEVNRTGNVLTLEFDDGSKIIINSQAPMQELWVAARAGGFHFRRGDDGRWVDTRSKEELYVALSRYISQQSDVDVTLAAG
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: GLYCO_NCMV
Sequence: MQKLSLVWIITLSVSVITGDGLSILSCNKTDEVPTVTQCFKSCSDTILGEQVKVSILSQEDPTSIVVGRCIWRIMKQSFTETWTFSRLISAKEITWEPATTQECNGAFHNLCKNKAGCVSEDLEIEPEFSWARTEIREVKHLSIETLTMSAYLHQGAGKVLIDGVAVPISKKTHNNGDFTYVWDDVPISEVCPWKHPISHLSCYKDKEDLDDIYCPSQGISLVNYTKVDTSCPEQIYTDVGGLVFKLGKVDFNDWYPYVIESSDVAVKETISSINMALKMRESVHCHQDCLEIRRRVTYVDGFYYDPLPPAKCRLIGNCSVDSGSVTCNNGTLVWATCGGRRVWIDLKSGRDVKNAVCEKGGRSRISKNQFEGVLNEFHLNNSKFGNILRANEIHSVILKDNEVMDFARVVKSASERSGNFSEGTLINVRQLFRPMINFLRGIEHEIKVVAFSVLALIVGYIIIRIRTVTVAKAKSLESIAMI
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the cytorhabdovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: ALGD_PSESM
Sequence: MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGLATGKLRGTTDFAEAIRATDLSMICVGTPSKKNGDLELDYIESVCREIGYVLRDKNTRHTIVVRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDLPPMTVIGEFDKASGDVLQSLYEELDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGREVMDVVCQDKALNLSQYYMRPGFAFGGSCLPKDVRALTYRAGSLDVDAPLLNSLMRSNTSQVQNAFDMVASYDTRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGANKDYIESKIPHVSSLLNSDFDQVINDSDVIILGNRDERFRSLANKTPEGKRVIDLVGFMTNATTEDGRAEGICW
What is the function of this protein?
Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization.  The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
What are the official names of this protein?
GDP-mannose 6-dehydrogenase, GMD.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.