PharMolix/UniProtQA huggingface dataset:
Protein: NFIB_MOUSE
Sequence: MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHSDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSTSPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQPNSSGQVVGKVPGHFTPVLAPSPHPSAVRPVTLTMTDTKPITTSTEGEAASPTATTYTASGTSQANRYVGLSPRDPSFLHQQQLRICDWTMNQNGRHLYPSTSEDTLGITWQSPGTWASLVPFQVSNRTPILPANVQNYGLNIIGEPFLQAETSN
What is the function of this protein?
Transcriptional activator of GFAP, essential for proper brain development (PubMed:15632069, PubMed:30388402).  Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2.  These proteins are individually capable of activating transcription and replication (PubMed:30388402).
What are the official names of this protein?
Nuclear factor 1 B-type, NF1-B, Nuclear factor 1/B, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/B, NF-I/B, NFI-B, TGGCA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CTF/NF-I family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HDFR_ECOLU
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIATLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: FMT_HERAR
Sequence: MKIIFAGTPEFAAVALAALHAAGFEIPLVLTQPDRPAGRGMQLQASAVKQFALAHKIPVAQPISLRLDGKYPDVAQEAHDLLRATPHDVMVVAAYGLILPQSVLDIPPLGCLNIHASLLPRWRGAAPIHRAIEVGDEKTGITIMQMELGLDTGPMLLMESLPIAADDTTASLHDKLARLGGEMIVEALLKLEKGELTATPQPEAGANYAAKIAKEEATLDLRQSAQELARKIRAFNPFPGAMGICNGTPVKFWQAQALECSNQWPAGQVISANAQDGVVIACGDGALRVTELQKPGGKRLPAAEFIKGFALEAQRFQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: REX_STRP7
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THYF_PIG
Sequence: QAKSQGGSN
What are the official names of this protein?
Thymic factor.
Protein: THIC_SYNSC
Sequence: MIHGQTSTPGLSVAPQIMRASWVESRKGQANVSQMHYARQGVVTEEMAHVAKRENLPESLVMEEVARGRMIIPANINHTNLEPMAIGIASKCKVNANIGASPNASDAAEEVKKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIGASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHHRQNPLYTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELHTLGELTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNADDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKVLEANTGAAELTPVKLDKAD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TLR13_MOUSE
Sequence: MSGLYRILVQLEQSPYVKTVPLNMRRDFFFLVVTWMPKTVKMNGSSFVPSLQLLLMLVGFSLPPVAETYGFNKCTQYEFDIHHVLCIRKKITNLTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENLTLLNLVENKIQSVNNSFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISDFSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLVSLTHLSFEGNKLRELNFSALSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLRAMDLSNWELRHGHLDMKTVCHLLGNLPKLETLVFQKNVTNAEGIKQLAKCTRLLFLDLGQNSDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSSLQNLTSLDLSHNKFKSFPDFAFSPLKHLEFLSLSRNPITELNNLAFSGLFALKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLNHGTFRPLKKLQSLILSHNCLKILEPNSFSGLTNLRSLDLMYNSLSYFHEHLFSGLEKLLILKLGFNKITYETTRTLQYPPFIKLKSLKQLNLEGQRHGIQVVPSNFFQGLGSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNASLFQNLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNLKSLMFFDVYGNKLQCTCDNLWFKNWSMNTEEVHIPFLRSYPCQQPGSQSLLIDFDDAMCNFDLGKVYFLCSFSMVLSTMVFSWFSTKMIASLWYGLYICRAWYLTKWHKTEKKFLYDAFVSFSATDEAWVYKELVPALEQGSQTTFKLCLHQRDFEPGIDIFENIQNAINTSRKTLCVVSNHYLHSEWCRLEVQLASMKMFYEHKDVIILIFLEEIPNYKLSSYHRLRKLINKQTFITWPDSVHQQPLFWARIRNALGKETVEKENTHLIVVE
What is the function of this protein?
Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria.  TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin).  May also recognize vesicular stomatitis virus; however, these data require additional evidences.
What are the official names of this protein?
Toll-like receptor 13.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type I membrane protein.
Protein: TSYL2_MOUSE
Sequence: MDRPDEGPPAKTPRLSSSEPRQRDLPPPPPPPLQRLPLPPPQQRPRPQEETEAAQVLADMRGVGPTLPPPLPYVILEEGGIRAYFTLSAESPGWDHAMESGFGEAPSTGIMETLPSSEISGGSLAIDFQVAEPSSLGEKALETCSLGGWGPQMLVGPKRKEEAIIIVEDEDEDDKESVRRRQRRRRRRRKQRKAKESRERSAQRMESILQALESIQMDLEAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINQRDRDIFRYLTNLQVQDLRHISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHRGQEPQAYNRRSHDTRESFFNWFSNHSLPEADRIAEIIKNDLWVNPVRYYMRRGGYRSSRKKQHGKERAKNQYEMVIMEDAHDHYAIEDILSDISEIDEITDNETIHDIKISDFMETTDYFETTDNEVTDANENLCDSENPDHSEGYNTKITDNKGSVAANPDDNSDDPEEKNTYDSEDSNSEKADGDNTTLRDNQQVTNIQDSSDSDNGDEGSDDEDDDGNEGDNEGSDDDDDDNEGSDDDDRDIRYYKNGPEVFDKALDNRTNQNDYEEEVELISEDSVEEEEETSEEASQLSEDSYEDERIYGEERSEVNSEDSDIQEVLPVPKAWASLGKKGKIG
What is the function of this protein?
Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly.  May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
What are the official names of this protein?
Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, CASK-interacting nucleosome assembly protein, Differentially-expressed nucleolar TGF-beta1 target protein.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons.
Protein: DNAE2_BORBR
Sequence: MSAILPGYAELHCQSNFSFLQGASHPEELVTRAGELGYAALALTDECSLAGVVRAHVEAREQKLPLIIGSSFTLQAGADAPPLDLTLLAQNREGYGNLAELITLGRGRAAKGQYLLTPADIEAPAGDNAHLRGMPDCLAILAPPPGLAAERLAEQARWLAAQCPGRAWIGLTLLHHCRDDLHRAAVEHAAHASGLPIVALGQAQMHRRSRKPLHDTLAAIRTGRSVGQCGYDLAANAERHLRSRLRLASLYPAQALAQTLAIARRCTFSLDELQYEYPDEIVPAGHTPASYLRQQTYLGARQRFPEGMTPAVAAQVEKELALINELRYEAYFLTVYDIVGYARSQGILCQGRGSAANSAVCYCLGITAVDPARGNTLFERFISKERNEPPDIDVDFEHQRREEVIQYIYEKYGRQRAALTAVVISYRPRSVLRDTGRALGVDNGIIDAVARAHQWWDGKKEMLRSLAACGLDPASRVARQWAELAETLMGFPRHLSQHPGGFVISRGKLSRLVPIENAAMPGRSVVQWDKDDLDALRLLKVDVLALGMLSVLRRALALAGQRRGRPLALHEIPPDDDATYDMICAADTIGVFQIESRAQMSMLPRLRPRQYYDLVVQVAIVRPGPIQGGMVHPYLRRRQGREDITYPGPAVRKALARTLGVPIFQEQVMQIAVDAAGFTPGEADALRRSMAAWRRKGGVDKFRAQLVGGLLARNYTADFAQALFRQIEGFGEYGFPESHAASFALLAYASSWLKCHEPEAFLAALLNSQPMGFYAPAQLVQDARRHGVRVLPADVLYSGWEASLQDAPGAARPAVRLGLNLVKGLREDSARAIEQARVRRPFADTADMARRAGLPRQALDALAAADALRTLAGHRRLASWQAAASAQSRDLLREAVIVETETPALPAPSEGQTVAADYRSVGLTLGRHPLALLRPQLAARNFQTAAVLNTYPNRRLARACGIVTVRQRPQTAKGTIFVTLEDETGPINAVVRPELIERQRRELLDATLLGIYGTWQSVDGVRHLVAQRLVDLSSLLGQLSQDGLAAASRNFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_LISMF
Sequence: MSKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVPEARMLLITPYDKTILGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDSITKDKEAEILEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM79_BOVIN
Sequence: MTEPETLALLEVKGPETLEKSPPQALVPNGRKLEGEDEVESLGAESSRVGSSAESPTAREGTEDGLDSTVSEAATLPWGTGPQPSAPFPDPPGWRNIEPEPPESEPPTKLEELPEDEASLLPEKAARAFVPIDLQCIERRPQEDLVVCCEASEGEHRRTFLPPRATHPEPPECKWAEAVVKPPGHSCGGCGGCGGREALRAVASVGAALILFPCLLYGAYAFLPFDAPRLPTMSSRLIYTLRCGVFATFPIVLGILVYGLSLLCFAALRPFGEPRREVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDALKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLSMLLWNFYYMFVVEPERMLTASESRLDYPDHARSASDYRPRSRG
What is the function of this protein?
Contributes to the epidermal integrity and skin barrier function.  Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity).
What are the official names of this protein?
Transmembrane protein 79, Mattrin.
What are the subcellular locations of this protein?
Lysosome. Golgi apparatus, trans- Golgi network. Membrane; Multi-pass membrane protein. Note=Colocalized with TGOLN2 in the trans-Golgi network. Colocalized with LAMP1 in the lysosome (By similarity).
Protein: FBX31_HUMAN
Sequence: MAVCARLCGVGPSRGCRRRQQRRGPAETAAADSEPDTDPEEERIEASAGVGGGLCAGPSPPPPRCSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCREEYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKGPHHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSHGLEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRNFNELSRIVLEVRERVRQEQQEGGHEAGEGRGRQGPRESQPSPAQPRAEAPSKGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQPFVLPVGVSSRNEDYPRTCRMCFYGTGLIAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAPSPQAFDEMLKNIQSLTS
What is the function of this protein?
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage.  Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest.  May act as a tumor suppressor.
What are the official names of this protein?
F-box only protein 31.
What is the protein family that this protein belongs to?
Belongs to the FBXO31 family.
Protein: PSF3_MOUSE
Sequence: MSEAYFPVESGALGPEENFLSLDDILMSQEKLPVRVETPMPRLGAFFLERGAGSEPDHPLPQGTKLELPLWLAKGLFDHKRRILSVELPKMYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLKTFIGRFRRIMDSSQNSYNEDTSALVARLDETERGLFQIGQRSLNDFQSWEKGQASQITASSLVQNYKKRKFTNMED
What is the function of this protein?
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks.  GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
DNA replication complex GINS protein PSF3, GINS complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the GINS3/PSF3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin.
Protein: TATA_LEIXX
Sequence: MLGGLTGWHLLIILAVILLLFGAPKLPALAKSVGQSMRIFKGEVNEMKKDGDKDKGEGGSTAPATDTGASSEQNSK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DEF1_DEBHA
Sequence: MSTQRKAYKNHSKRFSNNSSSSSNNNSSSTELTSLLEMFPDWESDDLSSLLAEHNNILEVVIDLIVNNKVSKWEPIKKEAKNKKKEKENDEFVNVPNTNVTSNNTTHTSSADHGHKLNKYHKEAHPSNSKSKFSSKGPHNKKPNPKFNGKDSSPTAPTTSTSTSTSGATSVPSSNSWAAALSKDGVKVNNKSHKESDSQPETELEPEPEPEPVAQAGEEHEIIIEQTTTVIESTETPTSTTKPVLKEATVPQPKQGSWASAITPKPKSKPRTKQALSGSQEESFESKGQFEQAQEEPVEAIIIEETTTTIPAESISSEETIEQPAQVVLPTSSQPLSSVGVSFGSLSLGDEEKESQPEQTTEEISAPVGEQSQQQQQQRYGLYNNQNQNQNQNRYNQQIYQQQQQHAQQQHAQQQQQQQPQQSQQSQQPQQPQQPQQPQQPQQPQQPQQPQQQPQQPQQPQQQYNQSKQQQQQQQQQYDYYNQFQQSQYPQQGSQTLPGAQFGVYPGMDYSAYNQQAAAAVVSSPAASPAATANYAQYAQAASQPPSSGAQEGNVAAQSPITSQINPNTLQQQVPAAPFGYPYYNYYYNTPFYGNGAGLGAQGGFGNVAAAQGTPTSNSNVTPNSGVNSGFMGVGNTGASQYYGQPNQFGNRYPGYNSYPQPGQAQSAQSGNPSNNQSGSVPASQGEANDSSSASNQAGNPQSQIPQQSQQPQQPGIPQYGGYQQYPQYGGYQDNNQYRGWY
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II.  Also involved in telomere length regulation.  Binds DNA.
What are the official names of this protein?
RNA polymerase II degradation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEF1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: YG21B_YEAST
Sequence: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDLKNQHSEIPQAKTKVGNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDDELSLGQQQKESKPTHTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKKRKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQNKQTKLDQFDYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQNRPGSTNEMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty2-GR1 Gag-Pol polyprotein, TY2A-TY2B, Transposon Ty2 TYA-TYB polyprotein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PROA_DICTD
Sequence: MENLIEKLKKAKVSSYTLALLNTNEKNEALRAIANNIEKNIDKIIKENEKDLKRGEEKGLSKAVLDRILLNEKRLRDIIKSIDDVIKLPDPVGEIVSMQKRPNGILVGQMRVPIGVIAIIYEARPNVTVDATILALKSGNAIVLRGSSDALNSNIIITEIMKEALSNTKVPPDTVQIIESPEHSVVEELLQMVDYIDVAIPRGSAKFIKHVMNISKVPVIETGAGNNHIYVEEDADFEMARKIIINAKVQRPSVCNAIEKLLIHKNIAEEFLPIIAKDLREYNVEIRGCKRTLKILTDAIPATEEDWYTEYLDYIIAIKIVESIDEAIEHINKYNTKHSEAIITKDYYKALKFLRMVDAAAVYVNASTRFTDGGEFGLGAEIGISTQKLHARGPMGLKELTTTKYVILGEGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPPED_HUMAN
Sequence: MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDEWEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIPLVLVSGNHDIGNTPTAETVEEFCRTWGDDYFSFWVGGVLFLVLNSQFYENPSKCPSLKQAQDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSKSTRKKLADKFIHAGVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSEKGIEDDLMDLIKKK
What is the function of this protein?
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis.  May play an inhibitory role in glucose uptake by adipocytes.
What are the official names of this protein?
Serine/threonine-protein phosphatase CPPED1, Calcineurin-like phosphoesterase domain-containing protein 1, Complete S-transactivated protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. CPPED1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_CITSI
Sequence: MAKGKEVRVRVILECTSCVRNGVNKESRGISRYITQKNRHNTPSRLELRKFCPYCYKHTLHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMA_SHEB9
Sequence: MNLAAMDPQTYDTQLEHKRIKLEQAFAQFETPSVEVFASEPANYRMRAEFRMWHDGDDLYYYMFDKVLNEKVRCDQYLPASVLINQMMSALIAELKPNPSLRHKLFQVDFLSTLSGEILVSLLYHRQLDDQWRADATALKAKLSSQFNVNIIGRARKQKIDLDKDFVVESLQVNDKTFLYKQIENSFTQPNAKVSVKMLEWAIDATQNSQGDLLELYCGNGNFSIALAQNFNRVLATELAKPSVDAAQYNIEVNGIENLQIIRMSAEDFSDAMAKKRSFRRLEGIDLDSYVCNTIFVDPPRAGIDPDTLALVQGYERILYISCNPETLKDNLQQLNETHKVTRFALFDQFPYTDHMETGVLLERR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: YKA4_CAEEL
Sequence: MNALIVKSALEYLELSTVVAILIIIACALLSYQISARRPLYYNLFVVEMHTWTTRRMVQVLHLGQEFTPPVTWERLVQRMRARAPRIQGEQRVAISDTNIVIQSPNTVIDSPAPARSPDVDLITLWDIEMPPPSAGHVPDATRDSQYAAAAAIAILARGDDASLMSRTYRPQLRPPTERSGNTRVDESRPSENSSRHDYVTTDVTYTTPSINPDMQHHLSTRTSNVTQTQPPTNQVFADTPELTEDIVIDQQEEDDEEDDDDDSSDDAIIEDHEEEEGQDDDEETEIEIDRGGPIEEIEQVEVEQNEDPPLDDQEVEAQPEQVLQETKESEFPVIEGPSEGKILIKLKFMNDTEKNTYASLEDTVAKFKVDHFTNLANQVIRLIYQGQLLREDHRTLEEYGLQPGSIVHCHISTTPYTRPGIATLPPIVNNGFRRRPRRSVRAPRDTTPMPSESVPVVDENVTTARRRAAQDRNVGQIYLLLSTMVPILSGIGLAFFRPDRIRDLLRPATLLTISQWVCNLLVDNGLLEQDDDDQETHLQTSTLFWIFGGQMVAVSIFLYYFPDVFDRVGFSIFIIVFLYFVFVVYSRQRRRQPDPVEVQNEMMENQIVQETIRLL
What are the official names of this protein?
Uncharacterized protein B0303.4.
Protein: YR257_MIMIV
Sequence: MMGINSVYSKPISEIEFASAMNSVKNRFGVDENEWYIYLESEDYIYDQRLIEKGMEPKHSDTHRKFPKIIKNGQIDIDNIGDDFMLPDPIALIKEWQSSPNSWEKKVVSVMKTLGDFKNVIKILDIGSSNDCINPVSSGLTRPLEGREKIVSDIVQNLISRMSTIDTTDKNKSRQYQQEINTIVATYNSFHPVWSFVKLSKLNYWSKEIEVPFIRKGNRAINDINVNLRPSEDLKVSPTDKQFSQGYIPYLINKMVLGDIPNEIAAIVFNNTIVIDGLNLSEGQRLRAVLLSGNSRDSFDNRCIFKCKHFLENFFRENTIKEYNYTRYVKISIPK
What are the official names of this protein?
Uncharacterized protein R257.
Protein: CIPKL_ORYSJ
Sequence: MQKTSMNPVTDPVAAATGRVAIRQLPIKTQPNSQSLTPFLQLPPKPPPNLLFSSPLASVELRHRARARRRRRPSHPRRAPAMRMGKYEMGRALGEGHFGKVKLARHADTGAAFAIKILDRQRILAMKIDEQIKREIATLKLLKHPNVVRLHEVSASKTKIYMVLEYVNGGELFDKIALKGKLSEKEGRKLFQQLMDAVSYCHEKGVYHRDLKPENVLVDAKGNIKVSDFGLSALPQNQRKDGLLHTTCGSPNYIAPEVLLNRGYDGSLSDIWSCGVILYVMLTGNLPFDDQNTVVLYQKILKGDARIPKWLSPGAQDILRKILDPNPITRLDITGIRAHEWFRQDYTPAMPFDDDDDNNISDGNLHMTENQDIETSPAISQINAFQLIGMSSCLDLSGFFEKEDVSERKIRFVSNYSPTSLFEKIESTVTEKGFQVQKNSGKLKVIQVCKEPANPRGHGNLLISAEVFEINESLYVVELKRSSGDCSLYRQLCASLSEDLGICKRQQLLKKDSMRQDLCRYNSSF
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 21, OsCIPK21.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: GPDA_WOLSU
Sequence: MDVAIIGGGAWGSALYKALLEKSSVALVSRSGREGIHQCSLQEALEARFLVLAIASSALRGWLNEANLPPKTKILVACKGIEEGSGALVSEILEEFLPRENLAYLAGPSFAKEVREGLPCALVIHSHHLELAQEMSQFFPSWIRLYVENDVVGGEVCGAYKNVIAIAGGICDGLGLGYNAKASLVARGLVEMARFGQYFGAKIETFLGLSGAGDLFLTSGSTLSRNYRVGLGLAQGKSLEEILIELGEVAEGIKTARAITQIAQREGIHAPIAHEVNAILQGKNPKESLKDLLSHGR
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.