PharMolix/UniProtQA huggingface dataset:
Protein: EFTU1_CAUSK
Sequence: MAKEKFERNKPHCNIGTIGHVDHGKTTLTAAITIILAKSGGATAKNYADIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVYMNKVDLVDDEELLELVEMEVRELLSSYDFPGDDIPITKGSAKVAIDGGDPVIGEQSILALMKTVDDYIPQPDRPIDLPFLMPVEDVFSISGRGTVVTGRIEKGVVKVGEEVEIVGIRAVQKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVERGQVLCKPGSITPHTKFVAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIIKLREGVEMIMPGDNAELDVELITPIAMDQGLRFAIREGGRTVGAGVVAKIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SYNP2
Sequence: MTKRTLGGTVRKQKRTSGFRARMRSHTGQNVIRARRKKGRHRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PR1_ASPOF
Sequence: MSSGSWSHEVAVNVAAGRMFKAAMLDWHNLGPKIVPDFIAGGSVVSGDGSVGTIREIKINNPAIPFSYVKERLDFVDHDKFEVKQTLVEGGGLGKMFECATTHFKFEPSSNGGCLVKVTASYKILPGVADESAKAKEGITNHMKATEAYLLANPTAYV
What are the official names of this protein?
Pathogenesis-related protein 1, AOPR1.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOA1_ENCCU
Sequence: MLKIYEDIINEVISRLEQVEDEVSIGKSAIHELRNEWRERLIEYTQSEWDGERMRRRDGEQGYHGYERLSEGPAHAFGGKPTTAKDPGMFEDYGSSDVSSGDSEIIGTKGSTGNCMVCLYVKVNMSKGKWKCTFKQGFISIGNIDFVFNSAQGELEW
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.
What are the official names of this protein?
Transcription initiation factor IIA large subunit, TFIIA large subunit.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_STRSV
Sequence: MKLNEVKEFVKELRGLSQEELAKRENELKKELFDLRFQAAAGQLEQTARLKEVKKQIARIKTVQSEVK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: EFTU_STAAB
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECR_CANLF
Sequence: HSDGTFTSELSRLRESARLQRLLQGLV
What is the function of this protein?
Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis (By similarity).  Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells (By similarity).  Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content (By similarity).  Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (PubMed:3626755, PubMed:13879310).  Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid (PubMed:13879310).  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation (By similarity).  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation.  Also able to stimulate lipolysis in white adipocytes (By similarity).  Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (By similarity).  Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (By similarity).
What are the official names of this protein?
Secretin.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_ALBFT
Sequence: MLSVKIELLEALHQALEKLSPGAGSKAVFESPKVAAHGDLATTAAMQLAKPLKLNPRQLAENLRAELLVRAPFERWVEAIDIAGPGFINIKLKPEAKQQTVREVLSQGQQFGSQPGTGKRMLVEFVSANPTGPLHVGHGRQAALGDAICNLYQTQGWAVYREFYYNDAGVQIGTLASSTQLRARGFKPGDPEWPSGENAAAYNGDYIADIAADYLAKKTVHSDDRAFTASGDVEALDDIRLFAVAYLRHEQDLDLKAFAVHFDNYYLESSLYLSGKVDDVVKRLHDAGKTYEHDGALWLKSTEYGDDKDRVMRKGDGSYTYFVPDVAYHISKWERGFEKVVNIQGTDHHGTIARVRAGLQAANVGIPKGYPDYVLHTMVRVVRGGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAKNNDNPVYYVQYAHARICSVLAAWREKEGGDVASLGQADLSPLQSPQALALLLLLAKYPEMLTAAAAGFAPHDVTFYLRELAACYHSYYDAERILVDDDLIKRARLALVAATAQVLHNGLAVLGVSAPQKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_SACD2
Sequence: MPRRRVVAKREVLPDPKFGSSTLAKFMNHVMISGKKSTAEKIVYGALDIVSEKLNKDPLETFSEALENISPLVEVKSRRVGGATYQVPVEVRPARRTALAMRWLVEYSRNRGEKSMAQRLAGELIDAAQSKGGAVKKREDVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ZDH14_HUMAN
Sequence: MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLVLILVTSGLFFAFDCPYLAVKITPAIPAVAGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQTGFLNALKDSPASVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRGYIQPDTPQPAAPSNGITMYGATQSQSDMCDQDQCIQSTKFVLQAAATPLLQSEPSLTSDELHLPGKPGLGTPCASLTLGPPTPPASMPNLAEATLADVMPRKDEHMGHQFLTPDEAPSPPRLLAAGSPLAHSRTMHVLGLASQDSLHEDSVRGLVKLSSV
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.  May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and thereby regulate G protein-coupled receptor signaling (PubMed:27481942).  May play a role in cell differentiation and apoptosis (PubMed:21151021, PubMed:24407904).
What are the official names of this protein?
Palmitoyltransferase ZDHHC14, DHHC domain-containing cysteine-rich protein 14, DHHC-14, NEW1 domain-containing protein, NEW1CP, Zinc finger DHHC domain-containing protein 14.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Protein: CBPYB_ARTBC
Sequence: MELYLNMLSFWYILLATSFFGPSQAVYQAPLSVDESQKVTIEEGFQIFTSKHSPQHSIRIKKQDGSICDAHSAQYTGWLDIGPKHLFFWYFESQNDPENDPLTLWMTGGPGYSSMLGMLEEVGPCLVNEYGNGTKYNPWGWSKKSSMLFVDQPVGVGFSYGDEGHDIPNDSYLAAVDMHRFLQLFISEVFPNKLNSPFHISGESYGGHYIPYLGAQIVRQNKLYPNEPQVQLKSCLIGNGCMSHMHTTFGYWETLCTTNPGVEKPIFNETRCDIMAKNMPRCMKVAEVCRRNPDPAICLSAQSVCDEGITGLYNKESDVKGGRNRFDITTPCQADDICYVQGLHLQNYLNTKLVWDALSPPKEVKEYKFASKNVEHAFGLTSDSMVPSTEEVEFLLSNQIHIMSYQGNLDLACNTAGNLKWMHDIPWKGQAELSSKALVPWKSVLASTGKNETVGRMKEVKIRVTDSATFATRYAFVTVDNAGHMVPQDRPDVAFDLMNRWISGETFV
What is the function of this protein?
Involved in degradation of small peptides.
What are the official names of this protein?
Carboxypeptidase Y homolog ARB_05721.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL36_HAEIE
Sequence: MKVRASVKKMCRNCKIVKREGVVRVLCSDPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: P2C06_ORYSJ
Sequence: MEDVAVAAALAPAPATAPVFSPAAAGLTLIAAAAADPIAAVVAGAMDGVVTVPPVRTASAVEDDAVAPGRGEEGGEASAVGSPCSVTSDCSSVASADFEGVGLGFFGAAADGGAAMVFEDSAASAATVEAEARVAAGARSVFAVECVPLWGHKSICGRRPEMEDAVVAVSRFFDIPLWMLTGNSVVDGLDPMSFRLPAHFFGVYDGHGGAQVANYCRERLHAALVEELSRIEGSVSGANLGSVEFKKKWEQAFVDCFSRVDEEVGGNASRGEAVAPETVGSTAVVAVICSSHIIVANCGDSRAVLCRGKQPVPLSVDHKPNREDEYARIEAEGGKVIQWNGYRVFGVLAMSRSIGDRYLKPWIIPVPEITIVPRAKDDECLVLASDGLWDVMSNEEVCDVARKRILLWHKKNGTNPASAPRSGDSSDPAAEAAAECLSKLALQKGSKDNISVIVVDLKAHRKFKSKS
What is the function of this protein?
Probable protein phosphatase that may function in abscisic acid (ABA) signaling.
What are the official names of this protein?
Probable protein phosphatase 2C 6, OsPP2C06, ABI1-like protein 1, OsABI-LIKE1, OsABIL1.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Localizes predominantly in nucleus.
Protein: LUPS_BRUGY
Sequence: MWRLKIAEGGNNPYIYSTNNFVGRQTWEFDPEAGTPEERAQVEEARENFWRDRFLIKPSSDLLWRFQFLSEKKFKQRIPQVKVQDGEEITREIATTALRRSVHLVSALQASDGHWCAENSGPMFFVPPMVFSLYITGHLNAVFSAEHCKEILRYIYCHPNEDGGWGLHIEGHSAMFSTVLNYNWLGKLGEGRDGGKDNACERARRRILDHGSATAISSWGKTWLAILGVYEWDGCNPMPPEFWAFPTFFPIHPARMLCYCRLTYMAMSYLYGKKFVGPITPLILQLREEIYNEPYDQINWSRMRHLCAKEDNYYAHTLTQIILWDAIYMLGEPLLKRWPFNKLREKALKITMDHIHYEDENSQYITIGSVEKPLLMLACWHEDPNGDAFKKHLARIPDYVWLGEDGIKIQSFGSQVWDTSFVLQALIASNLPSETGPTLEKGHNFIKNSQVTQNPSGDFRRMFRHISKGSWTFSDKDHGWQVSDCTAESLKCCLLFSMMPPELVGEKMGPQRMYDAVNVIISLQSKNGGCSAWEPAGAGSWMEWLNPVEFLADLVIEHEYVECTSSSLQALVLFKKLYPEHRRKEIEIFILNAVRFTEEIQQPDGSWYGNWGICFLSGTWFGLKGLAAAGKTYYNCTAVRKGVEFLLQTQRDDGGWGESYLSCPKKIYVPLEGNRSNLVQTALAMMGLILGGQGERDPTPLHRAAKLLINSQTELGDFPQQELSGCFMRNCMLHYSEYRDIFPTWALAEYCKLFPLPSKND
What is the function of this protein?
Oxidosqualene cyclase involved in the biosynthesis of lupeol.
What are the official names of this protein?
Lupeol synthase, BgLUS.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: UVRC_MYCCT
Sequence: MNLKEQVDLLTNKPGCYLFLNKDNEVIYVGKAKNLKKRVSTYFNKAYNIKTTRLIREITHLKYFIVDNEKESLLLEKNLIKKYRPKYNVLLNDDKTYPYIIITNQKDPMYKYVRKYEKKALRNYGPLPIGSNARSILLTLQRLFPLRMCKGDLKKPCLYYHLNQCSGACFKTVDSSYYEYQIKQVDKFFKGEINQVKQTLVKQMQKASDNLQFEQAKRIKDQITSLDFITAKQNVDIVTNKNIDVVNYEINEEKICFVMLFYRLGQLTYKDEYIQNYEGQDLDELLNSYLQQIYQKNLYPDVLLIPNEIDLLDLDENLLEFSSYSFNNQDDIFIKLAKQNAVDSLNKSILSNNVNSGDELEILDQLQQISNINKYPKRIEIFDISNIYNQFITGACIVYINAKPVRNEFRKYNIDSQYTSDYARMKFMLEKRFLKRIKEKEQLPDLIIVDGGIIQIHAAKEVLNKLNLKINVIGLSKDNNHKTRYLIDIFEQTIDIKNFKKLYNFLTSLQIRVDEYAKSGFRKKYHNQLNDQILLIKGVGKKTNLKLYKHFKTIDNIKNASFDELNKIINNKKITNLIISNFKK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_BACLD
Sequence: MLQIKEQLKQLTPYQPGKPIEEVKKEFNLDRVVKLASNENPYGCSEAAKEALQIEVQQMALYPDGYSAALRTKLASHLGVNETNIILGNGTDEVIQIISRSLLDPASNTVMANPTFSQYKHNAVIEGAEVREVGLLENGCHDLDAMLKAIDEQTKVVWVCSPNNPTGTYESGRNLIRFLEKVPEHVLAVVDEAYYEYVTAEDYPETIPLLERFPNLMILRTFSKAYGLASLRVGYGIASEQLIQAIEPARQPFNTNRLGQAAALAALGDQAFIHDCVRKNNEGLKQYYDFCDEHGLNYYPSQTNFVLIDFKRDADELFSELLKKGYIVRSGNALGFPTFLRISVGTKEQNEGFLKTLAGML
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: 6PGL_RHIME
Sequence: MSANMHIFENPSALAEALADDVGARLAAAIAARGTASLAVSGGSTPKAFFRSLSRRELDWSKVTVTLVDERFVPPENDRSNHRLVADNLLKDGAAEARFVPLYQAAETAEAAAAIASGRTASLGAPLDVVVLGMGTDGHTASFFPGGTRLEEALDPTTPRGVITMEAEGAGEPRLTFTFSSLQDAGYLVLHIEGSGKKEVLAQAEASGDEAEMPIRAMLRRAASPLQIYWAP
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: S27A4_PONAB
Sequence: MLLGASLVGVLLFSKLVLKLPWTQVGFSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLRERRTVPILFASTVRRHPDKTALIFEGTDTLWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDAQLHCLTTSRARALVFGSEMASAICEIHASLDPSLSLFCSGSWEPNAVPTSTEHLDPLLKDAPKHLPICPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGICIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANDKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDLERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDARKGRYVPLDQEAYSRIQAGEEKL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes.  Appears to be the principal fatty acid transporter in small intestinal enterocytes.  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (By similarity).  Plays a role in the formation of the epidermal barrier.  Required for fat absorption in early embryogenesis (By similarity).  Probably involved in fatty acid transport across the blood barrier (By similarity).  Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA.  Prevents light-induced degeneration of rods and cones (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 4, FATP-4, Fatty acid transport protein 4, Arachidonate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 4, Very long-chain acyl-CoA synthetase 4, ACSVL4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MALK_ECOL6
Sequence: MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMNFLPVKVTSTAIDQVQVELPMPNRQQVWLPVESRDVQVGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Maltose/maltodextrin import ATP-binding protein MalK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MUKB_PECCP
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFITALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVVNSRHQRVLVGVRLQQVAGRDRKVDIKPFTIQGLPTAIQPTQILTQVVGDRQARVLSLQELKDRVEEMEGVQFKQFNSITDYHSLMFDLGVVPRRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDGALELRRDLFSSRKQLSSEQYRHVEMARELAEQSGAEGDLETDYQAASDHLNLVQTAMRQQEKIERYNADLEELSYRLEEQNEVVEEAREQQAENEERADAAELEVDELKSQLADYQQALDVQQTRAIQYQQAQQALERARTLCQLPDLTADNADEWLDSYQAKEQEATEILLMLEQKLSVADAAHGQFEQAYQLVSKIAGAVNRNEAWQVARDLLRDSSSQRYQAERVQPLRMRLSELEQRLREQQDAERLLQDFSKRNGQDYQPEELESLQQELDARIETLSSLVAEAGERRMALRQELEQIQLRIQKLTTRAPVWLAAQEMLTQLSEQSGETFEDSRQVTEFMQQLLERERETTVERDDIASRKRQIEAQIERLSQPGGSEDPRLNALAERFGGVLLSEIYDDVTLDDAPYFSALYGPSRHAIVVADLSLVREQLAGLEDCPEDLYLIEGDPQSFDDSVFAVEELERAVVVKVAERQWRYSRFPEVPLFGRAAREMRLESLRDEREALAEQYATLSFDVQKTQRLHQSFSRFIGTHLAVVFDEDPEAEIRTLSSRRGELDRAIASFDGENQQQRQQYEQAKEASVQLNKLIPRISLLCDETLQDRVEEIRAELDETEESARFIQQHGATLVKLEPLVSVLQSDPQQHEQLQEDYAQAQNAQRQAKQQAFALTEVVQRRAHFSYADSAGMLGENAGLNDKLRHRLELAEAERTKAREQLRQHQAQLTQYSQVQASLKSSYDAKQDMLKELTQELQDIGVRADADAEERARQRRDELHAALSTNRSRRNQLEKQITFCEAEMDSLQKKLRKLERDYHQMREQVVTAKAGWCAVMRLVKDNGVERRLHRRELAYMEGDELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELNRLTEELTAREQMLAISSRSVANIIRKTIQREQNRIRMLNQGLQAVAFGQVKSVRLNVNVRETHTTLLNVLSEQQEMHQDLFNSNRLTFSEALAKLYQRLNPEIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGADGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESKRLRGKDIIPCRLLFLDEAARLDAKSIATLFELCDRLEMQLVIAAPENISPEKGTTYKLVRKVYQNNEHVHVVGLRGFGAEAPDTQEQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FK125_ARATH
Sequence: MPLPIFPSRLQCSSSSSSSSSRSSFFRPKLRIDPSLTLIPGLSNDVGRLILSFVPYPHISRIKSTCKSWYAFLSSKTLISLRHSRDNSNTNNLSHLLCIFPQDPSISPPFLFDPVTLSWRSLPLMPCNPHVYGLCNFVAVALGPYVYVLGGSAFDTRSYPLDVPLPTSSVFRYSFVKSVWERLSPMMSPRGSFACAAMPGSCGRIIVAGGGSRHTLFGAAGSRMSSVEMYDVEKDEWRVMNELPRFRAGCVGFLVENEKEKEKEEEGREFWVMGGYGGSRTVSGILPVDEYYKDAVVMDLRVDGGEKWRVVGDMWGEEERPKLGKIVAVDCGKPVFFMLDKDWILRYEMGLNRWRKESSVPKKAHYDKPVGFVALNGELHVMILLDGYNLMDTRHTRQQRKAGSLMIHMYDPKKKTWRSVVSKPPFNHQLDFRTTVMCTIRL
What are the official names of this protein?
F-box/kelch-repeat protein OR23.
Protein: PROA_DEIGD
Sequence: MTTETLTVRDLGLRARAAARVLRSLPTARKAAALHAIARELQAREGVILAANARDVAAAEAARLPAHMVARLRLDAASLAAIADDVAAVAQLPDPVGETTPERILPSGIRVSQRRVPLGVLGVIYESRPNVTVDVAALALMSGNAVILRGGKETVNSNAALEGAIRAALASENIPEDAVQVIRDPARERMLELLRLDDLVDAIIPRGGAGLHRFCVENATVPVIVGGIGVVHIYLDESFTRDPADVARAVNLIRNAKVQKPSACNALDTLLIHVRALPVLPAIARDLTAHGVTLRADPPALAALQTAGLEAQAATDADYGTEFLALTASIRTVSGLEEALDFIAAHGNHTDVILTRDPTQAERFVQDVDSAAVMVNASPRFNDGGQLGLGAEVAISTQKLHARGPMGLRELTTTKWVVVGDGQVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF2_ACACA
Sequence: MSWQTYVDTNLVGTGAVTQAAIIGHDGNTWATSAGFAVSPANGAALANAFKDATAIRSNGFELAGTRYVTIRADDRSVYGKKGSAGVITVKTSKAILIGVYNEKIQPGTAANVVEKLADYLIGQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-2, Basic profilin, Profilin II.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL2_DICNV
Sequence: MAIINHKPTSPGRRGRVDVTRPELHKGKPFAALVEKKTRGSGRNNAGRITVRHKGGGHAQKYRLIDFCRNKDGIDAVVERLEYDPNRTSFIALLRYSDGERRYVIAARDMKAGDIVRNGEDAPIKDGNCLPMRNIPVGSTIYCVELKPGKGAQLARSAGASAQMVAREGKYVTVRLKSGERRLVLADCRAVLGEVSNHEHSLRSYGKAGAKRWLGIRPTVRGVVMNPVDHPHGGGEGRTASGRHPVSPWGLPTKGYKTRNNKRTDSLIVQRRKKRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL34_STRSV
Sequence: MKRTYQPSKIRRARKHGFRHRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS2_CARRP
Sequence: MKIIHLINSDIFIGNNKKFLNFSMKKYIIFTINNLNIFDLKKIIISVLLLKKYIKFIYKKKMKILFIGTKNFFRELIYKFSRSIRQPFVCNKWISGSLTNLQNYKKMINKLKIIRKKIKFKSYTKKEKISFLKKEKKIEILFGGFRNLKKTPKLIIISDINKDKIIVNEAKRLKIKIASFLDSSDNCSKIDFILPCNNNSINSIKIILNILFKNLC
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RNH2_THIDA
Sequence: MTGRRTVSLHVGPVGLCGVDEAGRGPLAGPVVAAAVMLDPKRPIKGLRDSKKLTPAARERLADEIRARALAWCVAEASVAEIDRLNILHATMLAMQRAVAGMSHAPDDVWVDGDRCPEWTWRSQAVVQGDDKVAAIAAASILAKTVRDELMRGLHEAYPLYGFAQHMGYATAAHLAALKANGACPHHRRSFAPVRLLLDQTSLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_CALBD
Sequence: MNIALIAHDKKKELMVQFAIAYKFILSKHTLYATGTTGRLIQEATGLEVHRFLPGPLGGDQQIGSLIAYNQIDMVIFLRDPLTAQPHEPDVNALLRLCDVHNIPLATNIATAELLIKALDRGDLSWREIVNPKLQKNKSDK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.