PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_ANAD2
Sequence: MTTHNRPARVAEEFRHELSAILARGLKDPRITGFVTVTGSKMSPDLKEATVYVSIHGDERVRKDTFAGLQAAAGFLQREVSRALRLRNTPHLRFVYDESVARGDRIERLLREARTQGQAAPAPDVEPAPGAAPDDEAEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YF54_SCHPO
Sequence: MSHEFSPENTAVLFEAMKQEQHNRRRRVPMERRRRVVLACFNCKARKVRCDGANPCKACASNNLECTYPVKDEKEMDYSKDYFIDLSKRYKCLEYIVERLCSTKVSTYTTPSLIEVCNRISNQKSLLSSDVFSLNSESTNSQRDVDTLTQGALVCSQIQQDPTVVAEDTNNGINADASDQSVDEIMKLIGKIKVDSNGESRYIGASAGEAFVDSVQSELLVDPSFSELSAYSHTHHSYPPNEHDVNAVQKALSLLPPPEVSDFLIKSFYGHVQANFFFFHETLLRYRLNLIMSFQNPSVDPGFLCLLMMIFALGSMFAHMEIRSASNPFDNPGKQFFDTARLLLPQVIQQCKPSLVQASILMGLYLQSTLSQKSSYTYFGLSLSAAVANGLHRSCENPNIDPKTKELRNRLWWSVYTMDRLISIATGRPLSIADSECDAALPTVVPELEIEGSASNVHNIISMSKIAKIMGKTMEQLYGTVNYKKNPINIIESLRADLEEWKRSLPPFQILENLDAEDPLFRANVHLHMTYDQAIIIMSRPVLLHKMKNAKNSPRVDRINEDCILAARHLISLVHLLQNHSQLSCYSFFDYNYTFSSALVVLLHCVTEPCEEDDIAMQYAYSALDYMAEGNEAAKNCARVIRLFDAHLKGARSDGNGNTSQSGFMAWQRWIAEVSAKDEPEKLMSPYNKSIGGGRNSNSLTPNANLGADVSFFPTDDTSFLLDHSKLDDDLEKFASTLDPIKTTPDLANDSSLLNWANTDQGMDIEGSWLGNMHPTWLDYVCP
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C3C7.04.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPZ1B_WHEAT
Sequence: MATTLATDVRLSIAHQTRFALRLASTISSNPKSAASNAAFSPVSLHSALSLLAAGAGSATRDQLVATLGTGEVEGGHALAEQVVQFVLADASSAGGPRVAFANGVFVDASLLLKPSFQELAVCKYKAETQSVDFQTKAAEVTTQVNSWVEKVTSGRIKNILPSGSVDNTTKLVLANALYFKGAWTDQFDSYGTKNDYFYLLDGSSVQTPFMSSMDDDQYISSSDGLKVLKLPYKQGGDNRQFSMYILLPEAPGGLSSLAEKLSAEPDFLERHIPRQRVAIRQFKLPKFKISFGMEASDLLKCLGLQLPFSDEADFSEMVDSPMPQGLRVSSVFHQAFVEVNEQGTEAAASTAIKMVPQQARPPSVMDFIADHPFLFLLREDISGVVLFMGHVVNPLLSS
What is the function of this protein?
Inhibits chymotrypsin and cathepsin G in vitro.
What are the official names of this protein?
Serpin-Z1B, TriaeZ1b, WSZ1b, WZS2.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: MNN5_YEAS7
Sequence: MLIRLKKRKILQVIVSAVVLILFFCSVHNDVSSSWLYGKKLRLPVLTRSNLKNNFYTTLVQAIVENKPTDSSPDLSKLHGAEGCSFANNVAAHDSGHDSDLSYESLSKCYNLNKTVQESLREVHSKFTDTLSGKLNFSIPQREALFSGSEGIVTIGGGKYSVLAYTMIKKLRDTGTTLPIEVIIPPQDEGEDDFCKNWLPKFNGKCIYFSDIVPSKPLSDLKLTHFQLKVFGLIISSFKRIIFLDADNYAVKNLDLAFNTTSFNDTGLILWPDFWRRVTPPAFYNIIGSSIDIGKRVRFVSDDISPVSRYDPFVSNSNDYTPKERQEHFLKHVPLHDLDGTMPDLSSESGQMVIDKIRHFNTLLLALYYNVYGPTWYYKMISQGTAGEGDKDTFVAAAHALNMPYYQVRTKFEFDGFFYQKDDYKGLALLQHDFEQDYKQYQKAQQEVKANIEEFSKLDPDYTLDNGFLKTLMVNDDGSDLDIMFIHASFYKADPWTLYHENRFIGPNGEQVRGFRKPHRYGMDFELFLFNDMSKSFCTTPKSQVIKFKYFTDKVNTPEWDAMCEYLTNHVNYLESTHKEAMGEKN
What is the function of this protein?
Responsible for addition of first and second mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose.  Implicated in late Golgi modifications (By similarity).
What are the official names of this protein?
Alpha-1,2-mannosyltransferase MNN5.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network.
Protein: ERG26_SCHPO
Sequence: MPMNSVLVIGSGFLGGHIIRQLCERENLRIAAFDLFENEKLLHELHGQFTMYTGDLTKQGDIERVFEEFHPRVVIHTASPVHNLARDIYFEVNVDGTANIIKACQKFNVDALVYTSSAGVVFNGADLINVDESQPIPEVHMDAYNESKALAEKQVLEASSESLKTAALRVAGLFGPGDRQLVPGMLSVLKNGQTKFQLGDNLNLFDFTYIENAAYAHLLAMDNLLSSNPTANGQVFFITNGQVIYFWDFARAIWAHAGHVPPYIIKFPRPVGMLLATAAEWVCYFLKKEPGFTRFRVQFSCANRYFNIQKAEDVLKYHPIVDLEEGIRRTLAWMDTEKKH
What is the function of this protein?
Sterol-4-alpha-carboxylate 3-dehydrogenase; part of the third module of ergosterol biosynthesis pathway that includes by the late steps of the pathway (By similarity).  Erg26 is a catalytic component of the C-4 demethylation complex that catalyzes the oxidative decarboxylation that results in a reduction of the 3-beta-hydroxy group at the C-3 carbon to an oxo group (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane.  Firstly, the squalene synthase erg9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids.  Secondly, squalene is converted into lanosterol by the consecutive action of the squalene epoxidase erg1 and the lanosterol synthase erg7.  The lanosterol 14-alpha-demethylase erg11/cyp1 catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.  In the next steps, a complex process involving various demethylation, reduction and desaturation reactions catalyzed by the C-14 reductase erg24 and the C-4 demethylation complex erg25-erg26-erg27 leads to the production of zymosterol.  Erg28 likely functions in the C-4 demethylation complex reaction by tethering erg26 and Erg27 to the endoplasmic reticulum or to facilitate interaction between these proteins.  Then, the sterol 24-C-methyltransferase erg6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.  The C-8 sterol isomerase erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol.  The sterol-C5-desaturases erg31 and erg32 then catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol.  The C-22 sterol desaturase erg5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain.  Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase erg4 to produce ergosterol (PubMed:18310029) (Probable).  In the genus Schizosaccharomyces, a second route exists between lanosterol and fecosterol, via the methylation of lanosterol to eburicol by erg6, followed by C14-demethylation by erg11/cyp1 and C4-demethylation by the demethylation complex erg25-erg26-erg27 (PubMed:8586261) (Probable).
What are the official names of this protein?
Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating, C-3 sterol dehydrogenase erg26, C-4 decarboxylase erg26, Ergosterol biosynthetic protein 26.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
Protein: ATG9_PICPA
Sequence: MHKNNTTFLSRVFGINSRNIDVHNPLFADDSVIPLYDQNQSAYYDNAYSDYSSDEEDSKPRTSRQTDSNLHMTDHSGDGNDPFNQMDNSSRFSNSSSFHYNNTDQEDDNPELLLLQDEDSSLNRKNLDNSDFQSFAKKTFNQIPKIKFQLPKKEDYPTSHRQPPDIENQNGTLKSSVKKQIHFLDPMDKALWMWSNVSNLDTFLHQVYDYYTGNGFNCIMMNKFTELFTVVFIVWLFSFMGNCIDYDKLMNDRNVYQFSQVKIDKCYSKIGFFPQKLIYWLFFIGLCLKLYQIFLDYLVLKDMKLFFNLLLGLSDDELQTISWGLVVKRIMILRDKNINAIVSQNTDLTSRKRMNAHDIANRILRKENYMIAMYNKSILDLDIELPLIGKVQLLTNTLQWNLNIAILDYFFDSETGQINLPALKERNRHTISTELKKRLIFCGIINIVLAPILSIYFIMYYFLKFFYDFKTNPADISSREYSPYARWKLREFNELPHIFNRRLNISTESSNKYINQFPKETTTALLKFIMFISGSIVGVLVIVTILDPEFFLNFELTPGRTVLFYVSTLGAIFTICKNSIPDDTLVFDPEVSLRYLSQFTHYLPQEWEGKYHTEEVKNDFCKLYTLKLYLVGKEILSWLFLPYILCYKLPECADTISDFFREFSVHVDGLGYVCTFAMFQFNNQHNENGNANVHQNGNGNGGVPSAKSKSKKVPNPNRFTTKPSMRDMENDDKMIKSYMYFLESYGNDEIVQHQQALNRSLIYSTEISPTSGDDLNDSNILGLRQRNVATTGKRQNSIGNGLIYNGQNKRLSIGEAKTNVYSNPIASTVLDKDLQYKLANSYILNGMPGLNEANQPADRKNERKYSNDSPGVMKLVDKISQQHKA
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity).  Essential for the formation of the sequestering membranes and assembly of the micropexophagy-specific membrane apparatus (MIPA) which mediates the fusion of the sequestering membranes and incorporation of the peroxisomes into the vacuole during micropexophagy (PubMed:11533052, PubMed:16079180).
What are the official names of this protein?
Autophagy-related protein 9, Glucose-induced selective autophagy protein 14.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=The peripheral pool of ATG9 partially colocalizes with mitochondria and it has been speculated that ATG9 resides either in the mitochondria or within vesicles in very close to the mitochondria. During methanol growth, localizes to multiple structures situated near the plasma membrane referred as the peripheral compartment (Atg9-PC). During glucose-induced micropexophagy, traffics from the Atg9-PC to unique perivacuolar structures (PVS) that contain ATG11, but lack ATG2 and ATG8.
Protein: IRLC_DICDI
Sequence: MKSNYSTYLYKMSELERIVNGGDVSSIFIEQDDVLGEIKNFNYDLYTKYDSLVLKDPQTQNNSPKPPSLEIFILVNLIALCGRINDKFPNLDKFLTHYKYATNIFNLLSENIINSIEKFKETLSKDLPSFQLSVIANSSIVKKDNSIIKFLSCFGSFMKLESIEYFGSVFNSLIGEEDQFSLDLLQVLIDSSNEYKKFLQILEFNQLQKYYDDGHLCLFHSIKFDNLNEFKLLFNDSTWCQQQQQQQQINPQIFWFILCKYNSSKIAHYLLNDYQINKKSLKQKNPLEISPVTLLEIAFLCFSDKIAIVLFSQFNYHELLPKKSKMKHLIKSTSTLINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSKNIGLTQYTVLEGYFLINIRTRSRIAPFIEVLTMNGIHLTNDIIHTRIKSMSSDSIFRIFTEQYQQQQQNPLNNNQKQIQFNENFTRQQKIDFDNCPNEIDTFILDKTQCNLITLSQEFSIKVRAFTFYLSFGEIFTCSCEDYKREFSCKHMFFILLNYYHVPRNSYLIYQRQFTEIERYSIIMNIDLSKINSRIYGTPNFNTFFKIKSSPSSTTSPFQSINNNNNNNLNNNNNNNLNNNNNNENENKFKEDGDDEILQNLNRLNYILLRDFEFGPNDITTKLRETHINLFDRLLLIEDNLEALDKILKNFTQKGCTLSRDLVGDRNLLVLVAILDSTSKEKLSLLNKYWPLPEKTKKFAIPLIFFAISEECLKMFIQISPNLVKSTLNLHDWISILTEFALINETFLDHYPLLSAWYSDARSVETSLFRLFTCMDKIDCINYLIQTYLLPIPTFKNTLNNFETCYFFETYFLENSSIKAEQYLLEQELLEKKKQKEKKKQKQKQSKSKIINNPLSSSSSSSSSPSTSNTTITSTTPTTTTTTTTTTTPTTTTTTTTTSSPKQKPITPIKKEIEKEFEKIELTTPPPPLATTKQQQINENYDISIGKFKFNRKEENVLGRGSNGTLVFKGIWNNRIPVAIKQMQKMFNPLISKEIEVLITLTNKNCYNIVRYIDQEEDESCVYLGLTLCDGSLQNLVEKGDNNLTLTQFLGYDINSSSKNNSRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQHPFGDKFYRIVNILTDKPILEPLKHNLVACDLISQMISKNESDRPTIEKILLHPFFWNHEKKVKFIDASLNLFKDSNGLFTSKLNKLINYQEINLKNNIDSSSSNNNNNINSNVINNNNNNNNGMATNIPFLSKPWNQLIDQTLIEHIINKQNQLNGVGNNKKVIIYSFDQVKDLVRCIRNTIQHHKEIQRLVRQSPSSNGDNKQEVLDCLESQELVLSYFEEKVPDLLLFLYQKFKKHLDSKSLIYFNDLIIK
What are the official names of this protein?
Probable serine/threonine-protein kinase irlC, Inositol-requiring protein-like protein kinase C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NFAC3_HUMAN
Sequence: MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL
What is the function of this protein?
Acts as a regulator of transcriptional activation.  Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 (PubMed:18815128).  Along with NFATC4, involved in embryonic heart development (By similarity).
What are the official names of this protein?
Nuclear factor of activated T-cells, cytoplasmic 3, NF-ATc3, NFATc3, NFATx, T-cell transcription factor NFAT4, NF-AT4, NF-AT4c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin- mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Protein: CK5P3_DROME
Sequence: MNESEIPIDIHTLKLQDWLISRRIVPKNVQQELREIHRKISNALQDMPSNEQLIKLLARTNINYYHVKEIIEILKQTEKDTKSVFGTYGSQRMKDWQEISRLYEKNATYLAETAQIFVRNVNYEIPGVRKQMARLEQQADETQKRAHDLNKPESQILADHSALLEQLGVKGDNLHAEFVQVLSGLPELYDKSLVGIANIQPGIDLYAEVSGNKQVLPILNHLVEFGNTTVYQYIHKEAPLAVEEPPIRLNLSEGNASKDDNAVAEIDFGTDDNGGTSSTVSAEIIDYGDFGSGDLPESDGGNIDWGIESAPTDAVEINFDIPVEEYGIVVEGTGMDGGTAKGDQAYTLLDSPNYRDRFLDEIYELESFLRMRIYELKQLESSSDIMFSLMDNIATHDGESIWKILVSVEKIIQQTSDKQTQHLFQLKHSPKYANMLATKLQQMTKAVEKLRATREALKQLTIELREQRQDLNPVLEELIAQTRTLQSHIEKDISKRYKNRVVNLMGGVN
What is the function of this protein?
Probable regulator of cell proliferation.  May regulate CDK5, NF-kappa-B-mediated gene transcription and p53/TP53 activation.
What are the official names of this protein?
CDK5RAP3-like protein.
What is the protein family that this protein belongs to?
Belongs to the CDK5RAP3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RR3_AETGR
Sequence: MGQKINPLGFRLGTTQSHHSLWFAQPKKYCEGLEEDKKIRDCIKNYVQKNIRISSGMEGIARIEIQKRIDLIQVIIYMGFPKLLIEDKPRRVEELQMNVQKELNCVNRKLNIAITRISTPYGHPNILAEFIAGQLKNRVSFRKAMKKAIELTEQANTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIEAKIDYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: F16PC_STRSV
Sequence: MEQYKRILLKEFDSRQKVITELTNLEAILNLPKGTELYISDIHGEFAAFDYILRSCAGILNEKIKDCFGDSLSEVHKDRLSALVSYPELVLGEETKGQDWYQETIPQLLNLLAFAGAKYSRSKVRKALPPQYAYIIEELLYSDTALADKKSYFENILTYVIELREAVPFILGLSRSIRQLLIDHLHVVGDIFDRGVGSAQVIDELQHFHSLDIQWGNHDIIWMGAFFGSKACLLNVLRIAARYGYLWDIEKDYGLNLRSLTLFADKTYQSNPKFRPILGGREQEFSEEEILQLEKVHQALSIIQFKLENQLIKRRPEFQMQDHVMLDKIDYWEESITIDDTKHALVNTCFQTINPENPSALTPEENQAVDSMLASFQSSLKMAEHMSLLMNKGSMYKIYNKHLLFHGCIPLEPSGEFQPFILNQAHYAGKELLDFFEYHIRQAAKDKEVGDDLSTDLIWYCWKGKLSPLFGKEKMTTLERYFIEDKETHKEVENSYFSYRNSEKVCQLILEEFGLFSQESRMVNGHTPVKTGKGESPIRGGGLLFVIDGGLCKAYQKKTGTAGYSLLNNSYGFQLVTHQPFQNAQKVVESPFAQTSLKKVIENVEERTLIKSTTIGQSLLAQQQELFGLLHEFYDR
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: BH007_ARATH
Sequence: MANNNNIPHDSISDPSPTDDFFEQILGLSNFSGSSGSGLSGIGGVGPPPMMLQLGSGNEGNHNHMGAIGGGGPVGFHNQMFPLGLSLDQGKGHGFLKPDETGKRFQDDVLDNRCSSMKPIFHGQPMSQPAPPMPHQQSTIRPRVRARRGQATDPHSIAERLRRERIAERIRSLQELVPTVNKTDRAAMIDEIVDYVKFLRLQVKVLSMSRLGGAGAVAPLVTEMPLSSSVEDETQAVWEKWSNDGTERQVAKLMEENVGAAMQLLQSKALCIMPISLAMAIYHSQPPDTSSSIVKPEMNPPP
What are the official names of this protein?
Transcription factor bHLH7, Basic helix-loop-helix protein 7, AtbHLH7, bHLH 7, Transcription factor EN 92, bHLH transcription factor bHLH007.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_STRPQ
Sequence: MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCFRELAYKGQIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: THYX_TREPA
Sequence: MTLRTLQAGVAVSIALDRVCFFCYNGAVAHCVVEAAEDILDRRFSVLDKGFVRLIDYLGGDARIVQAARVSYGAGTRTARDDAALIDFLLRNKHTSPFEQVVLTFHVRAPIFVARQWMRHRTARISEVSSRYSLLSHDCYVPQETSVAVQSTRNKQGRASEGISPEQQQEVRAAFEAQQKAACAAYDALIQKNIARELARINVPLSLYTEWYWQIDLHNLFHFLRLRASAHAQAEIRAYAEVIIEITRAVAPCATASFENHEKDGVQFSGREFAALKALLAGEGLSLEGKERARFEEKLRSGLQQ
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: TNFL6_CERAT
Sequence: MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQKHTASSLEKQIGHPSPPPEKKEQRKVAHLTGKPNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCTNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWAHSSYLGAVFNLTSTDHLYVNVSELSLVNFEESQTFFGLYKL
What is the function of this protein?
Cytoplasmic form induces gene transcription inhibition.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 6, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Note=Colocalizes with the SPPL2A protease at the cell membrane. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted. Note=May be released into the extracellular fluid by cleavage from the cell surface. SUBCELLULAR LOCATION: [FasL intracellular domain]: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Protein: BAR1_CAEBR
Sequence: MDLDPNLVINHDDTNLSEISYTMEQDSSSYSLEMGGTPSSAGHRKVDMWQNHNFDSGFQTMNHSEAPSIISSLHPSSHLSGMSSMAEYEPIPNLSEQQKQKFDGITKNPTDGQYNTVRAIPELTMLMKDQDNEVVQKAVMIMQNIAKMECDAMRRQNETKIVDPCVIFTLRNLLRDKVDHPNIIRFTLGTLFNICNRQEGIDLVTRAISEQPDIIPNLIRHIGTFANSIYKYAILTMHSILSDKQRGGQSVTIARQQDAIIHVTPWLEAEKSEKLLPVIVDLIRVLCEKNTDQKVKFVKMGGPQKLLHILQQRGYENLLWRSTQLLKTFSNFDAPCLVAFGGRQILAGMLSHGSPRLVLSTLETLRNISDVPSKMKEELLLKSLLELVNSRNAVIRLYSAQTMSNLVANNRPNKEYMCSNNGVVNLCRALAIATKDWQNFQDKEAQQMEDYAESLICTLRHLCVGHPLAEKVQAYVFREPSIFLHKLMTMRPVLLKHTLNLLLKVVSQNALLAPFLLCRIGEIGFVEQLIHILRVACTQLNVQDVIEGVRVKDIVHLCIQILRLITRNPDILNEVDFFLRSPENSRMGDGHTLPIFVLQKANVEENTKSSTLELIYNLMHHEKMADHLERDEILCKMLHSVQMQAANHPELANLAANILKLMSEKRERNRIHYGRHGSFESQFGHLSVAAQRTEVLNSHGETYEGAGEQWSQPMSDDSMMESYCNSSGRDSSKTYNSPMYHSPPSMYPEYPNGPPSGPYYDPHAFTSTRPTPPHYANYDSPPVYNNIPSNQGPSSHLSDQYPYRQGRF
What is the function of this protein?
Participates in the Wnt signaling pathway which affects cell fate and may regulate the stem cell divisions of seam cells during larval development.  Functions as a transcriptional activator but is dependent on the interaction with pop-1.  Involved in maintaining lin-39 Hox expression and regulating glr-1 abundance at the synapses.  Required for mab-5 expression during Q neuroblast migration and for oxidative stress-induced daf-16 signaling.  Has roles in egg laying, vulva precursor cell fate determination, Q neuroblast migration, posterior ectodermal cell P12 specification, movement, body length, male tail development and dauer induction.  Functionally redundant to wrm-1 and hmp-2 (By similarity).
What are the official names of this protein?
Beta-catenin/armadillo-related protein 1, Protruding vulva protein 1, Suppressor of polyray 1.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cell junction. Note=Mostly cytoplasmic.
Protein: ZIPA_ECO5E
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPRPAQPVQQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: ISCR_ECOHS
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRIQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: Y557_STRPF
Sequence: MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFSEGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein MGAS10750_Spy0557.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CYB_COTJA
Sequence: MAPNIRKSHPLLKMINNSLIDLPTPPNISAWWNFGSLLAMCLITQILTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAVPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGITIIHLTFLHESGSNNPLGISSDSDKIPFHPYYSIKDILGLTLMLTPFLTLALFSPNFLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLILTWIGSQPVEHPFIIIGQMASLSYFTILLILFPMIGMLENKMLNH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.