PharMolix/UniProtQA huggingface dataset:
Protein: RL9_ECOL6
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NPY6R_RABIT
Sequence: MEVSLNDPASNKTSAKSNSSAFFYFESCQSPSLALLLLLIAYTVVLIMGICGNLSLITIIFKKQREAQNVTNILIANLSLSDILVCVMCIPFTAIYTLMDRWIFGNTMCKLTSYVQSVSISVSIFSLVLIAIERYQLIVNPRGWKPSASHAYWGIMLIWLFSLLLSIPLLLSYHLTDEPFRNLSLPTDLYSHHVVCVEHWPSKTNQLLYSTSLIMLQYFVPLGFMFICYLKIVICLHKRNSKIDRRRENESRLTENKRINTMLISIVVTFAACWLPLNTFNVIFDWYHEVLMSCHHDLVFAICHLVAMVSTCINPLFYGFLNRNFQKDLVVLIHHCLCFALRERYENIAISTLHTDESKGSLRVAHIPAGI
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.  The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
What are the official names of this protein?
Neuropeptide Y receptor type 6, NPY6-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_MAGMM
Sequence: MFNQHFDVVVVGAGHAGCEAAHAAATLGCRTLLSTQVIDSIGQMSCNPAIGGIGKGHLVKELDALGGVMGIVADQSGIQFKKLNQRKGPAVHGSRAQIDKMAYRKNMKKILDACANLEIKQAEVVELIIKNSCVVGVKTDWNEVYSCGAIVIATGTFLDGLIHIGERKFPSGRLGDKESHPLAVNIKSLGLKISRFKTGTPPRLDGRTVNIEKLNRQDGDAIPSPFSFMHDKIERPEMPCWIAQTSKETKQIIEKNIHRSAMYSGQIEGVGPRYCPSIEDKIKKFKEREVHQVFLEPEGENTNEMYVNGVSTSMPIDVQWQMIRSIVGLENAQIVKPGYAIEYDMVMPTELDHTLKTKKYDGLYLAGQINGTTGYEEAAAQGMIAGLNAARFAKKESSYRFERYDGYFGVMVDDLVTRGVDEPYRMFTSRSELRIVHREDNADMRLTPLGHELGLVGHKRWEKYLSKKKQYDLLEDLSQKFKINGQPVSEILKRTDCDLEKVCEAMQLDALSKNVLEIYKNDLIYSGYEKKIIAENSRVEKYRSHVLPKEIDWSKVASLSSEVRLRLEKSDCRTVADVIATKGVTPASVVNILIYLGLK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HA33D_CBDP
Sequence: MSQTNANDLRNNEVFFISPSNNTNKVLDKISQSEVKLWNKLSGANQKWRLIYDTNKQAYKIKVMDNTSLILTWNAPLSSVSVKTDTNGDNQYWYLLQNYISRNVIIRNYMNPNLVLQYNIDDTLMVSTQTSSSNQFFKFSNCIYEALNNRNCKLQTQLNSDRFLSKNLNSQIIVLWQWFDSSRQKWIIEYNETKSAYTLKCQENNRYLTWIQNSNNYVETYQSTDSLIQYWNINYLDNDASKYILYNLQDTNRVLDVYNSQIANGTHVIVDSYHGNTNQQWIINLI
What is the function of this protein?
The hemagglutinin (HA) component of the progenitor toxin protects the structural integrity of the neurotoxin; may increase internalization of the neurotoxin into the bloodstream of the host.  Involved in binding to the small intestine through interactions with glycolipids and glycoproteins containing sialic acid moieties (By similarity).  Erythrocyte agglutination only occurs when the entire complex is assembled (PubMed:17581814).  Binds eukaryotic host mucins as well as N-acetyl-beta-neuraminic acid, N-acetyl-D-galactosamine and galactose (but not glucose) via 2 sites (By similarity).
What are the official names of this protein?
Main hemagglutinin component type D, HA 33 kDa subunit, HA1.
What are the subcellular locations of this protein?
Secreted.
Protein: LAMA4_MOUSE
Sequence: MGWSTAWCSVLALWLLWCAVCSNAASGDGNAFPFDIEGSAVVGRQDPSETSDSGVTLGRLPPAAERCDAGFFRTLSGECAPCDCNGNSHECLDGSGFCLHCQRNTTGEHCEKCLDGYIGDSIRGTPRFCQPCPCPLPHLANFAESCYRKNGAVRCICKENYVGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEITGQCRNCLRNTTGFKCERCAPGYYGDARTAKNCAVCNCGGGPCDSVTGECLEEGFEVPTGCDKCVWDLTDDLRLAALSIEESKSGLLSVSSGAAAHRHVTDMNSTIHLLRTRLSERENQYTLRKIQINNSENTLRSLLPDVEGLHEKGSQASRKGMLVEKESMDTIDQATHLVEQAHNMRDKIQEINSKMLYYGENQELGPEEIAEKLVLAQKMLEEIRSRQPFLTHRELVDEEADEAQELLSQAENWQRLHNDTRSLFPVVLEQLDDYNAKLSDLQESINQALDHVRDAEDMNRAITFKQRDHEKQHERVKEQMEVVGASLSMSADSLTIPQLTLEELDEIIKNASGIYAEIDGAKNELQGKLSNLSNLSHDLVQEATDHAYNLQQEADELSRNLHSSDMNGLVQKALDASNVYENIANYVSEANETAELALNITDRIYDAVSGIDTQIIYHKDESDNLLNQARELQAKADSSNDEAVADTSRRVGGALWRKGALRDRLNDAVKQLQAAERGDAHQRLGQSKLFIEEANKTTAAVQQVTTPMANNLSNWSQNLQTFDSSAYNTAVDSARDAVRNLTEVVPQLLDQLRTVEQKRPASNISASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHPKVSVDDLKAFTSISLYMKPPPKPAEPTGAWVADQFVLYLGSKNAKKEYMGLAIKNDNLVYVYNLGMKDVEILLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFAGDDSLLDLTPEDTVFYVGGVPANFKLPASLNLPSYSGCLELATLNNDVISLYNFKHIYNMDPSKSVPCARDKLAFTQSRAASYFFDGSSYAVVRDITRRGKFGQVTRFDIEIRTPADNGLVLLMVNGSMFFSLEMRNGYLHVFYDFGFSNGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSTDNEKKKIPFTDIYIGGAPQEVLQSRTLRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYTSGSDVFSISLDNGTVVMDVKGIKVMSTDKQYHDGLPHFVVTSISDTRYELVVDKSRLRGKNPTKGKAEQTQTTEKKFYFGGSPISPQYANFTGCISNAYFTRLDRDVEVEDFQRYSEKVHTSLYECPIESSPLFLLHKKGKNSSKPKTNKQGEKSKDAPSWDPIGLKFLEQKAPRDSHCHLSSSPRAIEHAYQYGGTANSRQEFEHEQGDFGEKSQFAIRLKTRSSHGMIFYVSDQEENDFMTLFLAHGRLVFMFNVGHKKLKIRSQEKYNDGLWHDVIFIREKSSGRLVIDGLRVLEERLPPSGAAWKIKGPIYLGGVAPGRAVKNVQITSVYSFSGCLGNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMRNGQVIVKVNNGVRDFSTSVTPKQNLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPVDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDSRPVSFSKAALVSGAVSINSCPTA
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
What are the official names of this protein?
Laminin subunit alpha-4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: PYRB_METM5
Sequence: MRHLISMRDIGREEILNILDESERMEAILNEKGHCDFLNGRILATLFYEPSTRTRLSFETAMKRLGGNVIGFTDISNTSVTKGESLADTIKVISGYSDLIAIRHPSEGAARLSGENSKVPVINAGDGSNQHPTQTLLDLYTIKREVGHIENLKIAFIGDLKYGRTVHSLCQALSLFKGVEIKLISPEELKMPREVIEDIDGKIKLSEMTDVEIEDVDVVYMTRIQKERFVDVNEYYKVKGIYRLSKEHIGDKDVVIMHPLPRVDEIDSEVDNLPQARYFKQSFYGVPVRMAILKLLFEDSVK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TSGA_ECOLC
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSTAMFILGVVSGITMSIGTFLITQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSIEWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IPYR_ASHGO
Sequence: MSYTTRQIGAKNTLDYRVFIEKAGKVVSPFHDIPLYADEENQIFNMVVEIPRWTNAKLEITKEEAMNPIIQDTKKGKLRYVRNCFPHHGYIHNYGAFPQTWEDPNVAHPETKAYGDNDPLDVLEIGETIAYTGQVKQVKVLGVMALLDEGETDWKIIVIDVHDPLAPKLNDIEDVEKHLPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNRKYALDVIRECHEAWCQLVAGKAADDKKVSLANSTLQESVAYAPEVAAAVPAANPLPDAPIDKSIDKWFFISGSA
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO12_SULIK
Sequence: MAVYRCGKCWKTFTDEQLKVLPGVRCPYCGYKIIFMVRKPTIKIVKAI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 061R_IIV6
Sequence: MNDRGIIICVGIAFLIFIFLWAYFKNKKVKTGNYGNYSYYDKLTDRLDAKLGHDSSFMIQHYLDPENCPLYGDLPTLSQLVNLKQNNPSKYEELVNDGTVKRAVNIKALKTWLLLGSSNVDKFKHFMNQVNQLNIDKVDMLNLENALKYQLSKTQ
What are the official names of this protein?
Uncharacterized protein 061R.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SECA_ECOSM
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: LAT2_RABIT
Sequence: MEKGARHRHNTDKNHAGGSESEDFPEASSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLAVIVWIVTGLITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPDSGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGVVQICKGEYFWLEPKNAFDNFQEPDIGLIALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYITAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCLSTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLIFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFNDFIELLTLVSQKMCVVVYPEVDGGSGTEGTREDMEEQQQPICQPSPGKDKDSLEQSQP
What is the function of this protein?
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc.  Acts as an amino acid exchanger.  Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine.  L-alanine is transported at physiological concentrations.  Plays a role in basolateral (re)absorption of neutral amino acids.  Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity.  Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane.  Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
What are the official names of this protein?
Large neutral amino acids transporter small subunit 2, 4F2-LC5, L-type amino acid transporter 2, Solute carrier family 7 member 8.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Cytoplasm. Basolateral cell membrane; Multi-pass membrane protein. Note=Localized to the cytoplasm when expressed alone. When coexpressed with SLC3A2/4F2hc, is localized to the plasma membrane. Colocalized with SLC3A2/4F2hc at the basolateral membrane of kidney cortex proximal tubules and small intestine epithelia of the villi.
Protein: EBP_DICDI
Sequence: MEIFAFVPLAVLTALCVVISLFVKREKLVVFWLLWSGLIHIILEGSYGFFAHEVTKASTVSFTEKMLELVPLENAWNPHWYAQLYSQYAKYDLRYAIQDPMVVFFCFLELVQGAACFLLVICVIKQARIRHALQIFLCSIQGLGTVFYFITPYIYGLWEQQISSDPFELWVYVVGLNGLWLLVPIILTIQSFIAINKQFSIVESTTKDAKFISRKPKTA
What is the function of this protein?
Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.
What are the official names of this protein?
Probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, Cholestenol Delta-isomerase, Delta(8)-Delta(7) sterol isomerase, D8-D7 sterol isomerase, Emopamil-binding protein homolog.
What is the protein family that this protein belongs to?
Belongs to the EBP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THIO_STAAM
Sequence: MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: ENCP2_SYNE7
Sequence: MTDNAPQLALRDVAARQLANATKTVPQLRTITPRWLVRLLHWTPVEAGIYRVNQVKDASQITVACSERDESELPETFVDYIDNPREYLLSAVNTVVDVHTRISDLYSNPHDQIREQLRLTIEIMKERQESELINSREYGLLNNVAPGQLVHTRNGAPTPDDLDELLIRVWKEPAFFLAHPQAIAAFGRECTRRGVPPATVSLFGSSFITWRGVPLIPSDKVPLENGKTKILLLRVGESRQGVVGLYQPNLPGEQGMGLSVRFMGINRKALASYLVSLYCSLAVLTDDALAVLDNVDVTQYHTYRYN
What is the function of this protein?
Shell component of a type 2A encapsulin nanocompartment.  Expression in E. coli generates nanocompartments with an average diameter of 25 nm.  They can be disassembled by treatment with 6M guanidine hydrochloride and reassembled with cargo.  The nanocompartment is probably involved in sulfur metabolism (PubMed:33821786).  Probably allows passage of cysteine into its interior; during growth in light the physiological pH is 8-8. 4, about 30-54% of free cysteine (charge -1) would be able to pass through the shell (Probable).
What are the official names of this protein?
Type 2A encapsulin shell protein SrpI.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 2A subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment. Note=Unlike type 1 subfamily encapsulins, the nanocompartment has a raised protuberance around the 5-fold pores.
Protein: NNRE_DROVI
Sequence: MLKYLNQSEAINVDLELFNEYKFSVDQLMELAGLSCAHAVAKCFPAKDFARVLVCCGPGNNGGDGLVCARHLALMGYTPAIYYPKPTPKPLYENLAHQCQRMEICSITECPRVEEAADSYDLIVDALFGFSFKPPVRADFVSVVELLQQTKLPIASVDIPSGWDVEQGKLNDCDLEPTLLISLTAPKLCAKHFKGKHHFLGGRFVPPALQRKYELNLPAYPGNELCLEL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: Y818_DROME
Sequence: MFCEKPTEKREKSPCRCKNCVLRHSDFLPWPEPIGFTSDRKTDKDNNNHISTLQSVESVVTISDVNERHTTNHYKNHQSNPDEIAYTPNRSGVSSPVNDGASSPTQRGGTTPAPQGGKGGNSPSRVTAQPQAQPTILLIVVNKNDPPPYGQGQSWEYPGQQYSVPGPRGYPGPGPRGYPGPGPRGYPGRGPRGYPGPGPRGYPGQGPRRYSCPGPRGYPGPGSSGRPDPGGGLQGYYYPPSGPGNGTGPSGRPRPQNENEYAYYDRRRYSEAYQNNRNDWRGQPRGYYDGAYAEEHNLNRQPETRRNCQCPEKQQTPPPEETQNAQENDDQQTTKRKSFKRLVGMGVGNTCSCQGPSLMGSNLRSLGNEMDNQEVGRSGNMGTPPNTMEYLSERGSPPEIREVTVTDAKNKTYKCIQVPICISTGKANTCRCCKCAPSPDAENDESFDEDAECICNHEGKCTCVAGNEFPTEFGCECDLTNLEQTLRELIPNAECICYLKKKKRRRKRKKWAPKVYYDRFAGPPFVLNPKPRCLDYGRSPFCNPCYNPCSCAPFAKSCYTCDYNCEGCGRF
What are the official names of this protein?
Uncharacterized protein CG42266.
Protein: RUVC_SHEB8
Sequence: MAIILGVDPGSRITGYGVIQCQGRHQIYLGSGCIRTSSEELPGRLKQIFDGITEIIRQYQPDEFAIERVFMAKNADSALKLGQARGAAIVAATVANLPVAEYSATQIKSAVVGTGRAQKAQVQHMIQQLLKLPAAPQADAADALGVAVCHYHTSQSLIALSGRATARTYGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SHDAG_HDVAM
Sequence: MSRSERRKDRGGREDILEQWVSGRKKLEELERDLRKLKKKIKKLEEDNPWLGNIKGIIGKKDKDGEGAPPAKKLRMDQMEIDAGPRKRPLRGGFTDKERQDHRRRKALENKRKQLSSGGKSLSREEEEELKRLTEEDEKRERRIAGPSVGGVNPLEGGSRGAPGGGFVPSMQGVPESPFARTGEGLDIRGSQGFP
What is the function of this protein?
Promotes both transcription and replication of genomic RNA.  Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA.  RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome (By similarity).
What are the official names of this protein?
Small delta antigen, S-HDAg, p24.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RSSA_ASPFC
Sequence: MAPSQLPPIFNPTPQDIEMLLAAQCHLGSKNLQVHMEPYLWKTRPDGVNVINIGKTWEKILLAARIIAAIENPADICVISARPYGQRAVLKFASHTGATAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDAQAIKEASYVNIPVIALCDTDSPTEFVDVAIPTNNKGRHAIGLIWWLLAREVLRLRGTLATRETEWDVVVDLYFYRDPEAEENKEIADEAKVPGAEEIGAGAVESGFAGENWDTQAPGAGVPGTAFSAATAAPTSWEADGGDWAASSAAPAGESWAETQPAEAKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR771_MIMIV
Sequence: MSKYMGGKEASSVLGVHQRTLYQWDKKGWIKTIRTKGGKRLYDVGSYLADKDEESKEDHKLSICYVRVSSNNQKDDLERQIKFMKKKYPNHTIIKDISSGINMNRKGLNKIIDLAIEGRVKEVVVAYKDRLARFGFSLIERLIEKYSDGKIVVVRKKENQEPQEELMEDMMDVMNVFIARRNGLKKYSNK
What is the function of this protein?
Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.
What are the official names of this protein?
Putative resolvase R771.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: SEC11_ASPCL
Sequence: MLSFLSSNLSSTRQSLAQVLNFALVLSTAFMLWKGLSVFTASSSPIVVVLSGSMEPAFQRGDLLFLWNRSPRAELGEIVVYNVRGKDIPIVHRVVRTFPEVEGKAKKVKEITGTSSIPPNMLLTKGDNNVADDTELYAKNQDFLHREEDIVGSVRGYMPMVGYVTIMLSEHPWLKTVLLGIMGLMVILQREQ
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit sec11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: MAFB_HUMAN
Sequence: MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPLSTPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQPLQSFDSFRGAHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSDSPSSPEFFL
What is the function of this protein?
Acts as a transcriptional activator or repressor (PubMed:27181683).  Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells.  Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation.  Involved in renal tubule survival and F4/80 maturation.  Activates the insulin and glucagon promoters.  Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element.  SUMO modification controls its transcriptional activity and ability to specify macrophage fate.  Binds element G1 on the glucagon promoter (By similarity).  Involved either as an oncogene or as a tumor suppressor, depending on the cell context.  Required for the transcriptional activation of HOXB3 in the rhombomere r5 in the hindbrain (By similarity).
What are the official names of this protein?
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.