PharMolix/UniProtQA huggingface dataset:
Protein: GLPB_ECOLC
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: RS3_PSEMY
Sequence: MGQKVHPVGIRLGIVKDHTSVWYADGRNYADYLNADLKVRAYLQDKLKSASVSRIDIARPAQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMGVPVHINIEEIRKPELDGMLVAQSVAQQLERRVMFRRAMKRAVQNAMRIGAKGIKIQVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATYEAHTTYGVIGVKVWIFKGEVIGGRTEELKPQAPAPRKAAKK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ACCA_DICNV
Sequence: MNPEYLDFEQPIAELEYKLNELKQFSEQSKVDISDEVERLKTKLERLTGDIYSDLSDWQIAQVARHPKRPYTLDYIPHIFTDFRELHGDRHYADDMAIVGGLARLGQRSVMVIGHEKGRDTKAKVSRNFGMPRPEGYRKALRLMKLAEKFKIPVITFIDTPGAYPGVGAEKRGQSEAIARNLYEMAVLNTPIIACVIGEGGSGGALALGVADTVMMLQYGMYSVISPEGCASILWRDAAMAEEAVTILQVTSTRLKKLNLIDTIITEPSGGAHRDVAEMSRTLHDAFLSELDRLEAMDDATRIHQRLQKLRAYGNFLGE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNX_BACAC
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQLIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTPFETFHDVKTELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: END3_YEAST
Sequence: MPKLEQFEIKKYWQIFSGLKPIENKVNHDQVLPILYNSKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKNISSVPDELPDWLIPGSKVNLIKERKKRKQIENADLPPKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLSTKFFNISKTDLNKVWSLINPQNLPSIDRDPTFYFIHCLRQRNDLGAEIPASLPNSLAEVCNKKQLSYDLRSSQPPTKRKEEANEVDNLRDNGQNSSSDSSGSNVLSNEDSIKQKYASLTDDQVANMREQLEGLLNYKKSEKTQGGSKLSKRINIRSITDDLDNIEQQVEVLENYLNNKRHELQALQAEIN
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.  END3 regulates PAN1 function by preventing phosphorylation of PAN1 by PKR1 and is also involved in the correct localization of SLA1 to the cell cortex, in the bipolar budding of diploid cells and the correct distribution of chitin at the cell surface.
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: DEOC_CLOBM
Sequence: MKLSKYIDHTLLKPQATEKDILKLIEEAKTYDFASVCVNPSWVKLAYENLKDTNVKVCTVVGFPLGATSIASKVYETKVAIEDGADEIDMVIAVGQLKSGNDEYVKEEIKKIVEASKDKLVKVIIETCLLTEEEKVKACTLSKEAGADYVKTSTGFSTGGAKPEDIKLMREAVGKDMGVKASGGIHTREEMEVMIENGATRIGASCGVELVK
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_SINFN
Sequence: MPAYRSRTTTHGRNMAGARGLWRATGMKDSDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPAVFVSGGPMEAGKVVLHGKKHALDLVDAMVAAADDSVSDEDVKVIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLVVDLARRYYEQEDERILPRSVASKKAFENAMALDIAMGGSTNTVLHILAAAYEGEVDFTMDDIDRLSRKVPCLSKVAPAKSDVHMEDVHRAGGIMSILGELEKGGLINRDCPTVHSETIGDAIDRWDITRTSSETVRNFFRAAPGGIPTQVAFSQEARWDDLDTDREKGVIRSVEHPFSKDGGLAVLKGNIALDGCIVKTAGVDESILKFSGPARVFESQDASVKAILGNEIKAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHVSPEAANGGTIGLVREGDIIDIDIPNRTISLRVDEAELATRRAEQDAKGWQPAEQRKRRVTTALKAYAAFATSADRGAVRDLGDR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HIS6_PROM5
Sequence: MVALRLIPCLDVANGRVVKGVNFVNLRDSGDPVELACRYSEAGADELVFLDIRASVENRKTLVDLVSRTAKSVKIPFTVGGGINSIVTINDLLRAGADKVSLNSSAVKNPKIISQSSKKFGTQCIVIAIDARKKHNVSNEWEVYVKGGRENTGLDVVNWAKKVEELGAGEILLTSMDGDGTQNGYDLLLTKTVAKAVNIPVIASGGAGSLEDIFDVFTEGEASAALLASLLHDKKLTIEEIKSFLINKKLIIRPNEK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCSB_GEOSW
Sequence: MSFEKFFNTAVSSWMSQEGPDSDIVLSSRIRLARNIVDFQFPTVFNNEEAQQIVSLFEQTFAHRFYPSVGRFELLKMSELQPIEKRVLVEKHLISPHLAEDSPFGACLLSENEEISIMINEEDHIRIQCLFPGLQLTEALKVANELDDWIEEHVNYAFDEKLGYLTSCPTNVGTGMRASVMMHLPALVLTQQINRIIPAINQLGLVVRGTYGEGSEALGNIFQISNQITLGKSEEDIVEDLKSVVQQLIAQERMARETLVKTLNIQLEDRVFRSYGILANSRVIESKEAAQCLSDVRLGIDLGYIKNISRNILNELMILTQPGFLQQYAGGVLRPEERDVRRAALIRERLKMEERKAMEGDE
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: NOVL_STRNV
Sequence: MANKDHAPEHYVTRILAEATLDGARPVVRWRDTVITGTQLDRSVRRVVTALREAGVARDHAVAVLTQVNSPWMLIVRYAAHLVGASVVYITGANHGIVTHELPVATRVRMLREAGASVLVFDESNAQLAETVDETVRDKLVLCGLGHPASGTVSVDGRPVDDVSVDFTPEAPELAMVLYTSGTTGQPKGVCRSFGSWNAAALRGAAYPRPVFLTMTAVSQTVAMIVDTVLAAGGSVLLRERFDPADFLRDVGEHRVTETFMGVAQLYAILGHPDARTADLSSLRHVLYLGCPASPERLREAAALLPGVLAQSYGSTEAGRITVLRAADHERPELLATVGRAVPGVTIAIRDPETGHDLPVGEIGEVVVHGPEVMAGYVADPEHTARVIRDGWVHTGDFGSVDERGYVRLFGRMREVVKVQDTRVSPTEVEKVLVGCPGVVDACVYGHRGPDLIEELHAAVVLGTEGAPSFDTLRDHVARAMTPTHAPIRFVRWRRFPINNTGKVNRLRVREVSAEARGDSPDVLVDR
What is the function of this protein?
Catalyzes the formation of an amide bond between 3-dimethylallyl-4-hydroxybenzoate (ring A of novobiocin) and 3-amino-4,7-dihydroxycoumarin (ring B of novobiocin) in an ATP-dependent reaction in the novobiocin biosynthesis pathway.  Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
What are the official names of this protein?
8-demethylnovobiocic acid synthase, 8-demethylnovobiocic acid synthetase, Novobiocic acid synthetase, Novobiocin biosynthesis protein L, Novobiocin ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: METK2_RHORT
Sequence: MAQSEYLFTSESVSEGHPDKVCDRISDAIVDAFLAEDPHSRVALETMATTNFVVLAGEVRGPDSLTHDRLKEIAREAIKDIGYEQRGFHWKDAEIVSHVHSQSADIAVGVDAAGNKDEGAGDQGIMFGYACTETEELMPAPIALSHAILKSLAEFRHGGDTSFGPDSKSQVTLRYVDGKPVGAASVVVSTQHAGNLSQDEVRELVRPHVLKVLPEGWMCPEEEFYVNPTGRFVIGGPDGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLAEKCVIQVSYAIGVSKPLSVYVNTQGTGQVDEQRLAVVLQQLMDLSPRGIRQHLQLSRPIYARTAAYGHFGRKPEKDGGFSWERTDLVAGLKTAFGA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, MAT 2, Methionine adenosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BRASO
Sequence: MTARIIDGKIIAADLRAQVAREVERVKHDLGLTPGLAVVLVGNDPASEVYVRSKHTQTQAAGMASFEHKLPADVAQAELLALISKLNQDPSVHGILVQLPLPKGLDTEAVINAIDPAKDVDGLHPHNAGRLAGGQPALAPCTPLGCIILSKTVHASLEGMNAIVIGRSNLVGRPLVQLLLNENATVTIAHSRSRDLPALTARADLVYAAVGRPEMVKRDWIKPGATVIDVGINRIPTPEGKTRLVGDVAYAEVAEVAGAITPVPGGVGQMTVACLLVNTLRAACAIAGLPKPSV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GLMM_BACCQ
Sequence: MGKYFGTDGVRGVANKELTPELAFKIGRFGGYVLTKDTDRPKVIIGRDTRISGHMLEGALVAGLLSTGAEVMRLGVISTPGVAYLTKALDAQAGVMISASHNPVQDNGIKFFGSDGFKLTDEQEAEIEALLDKEVDELPRPTGTNLGQVSDYFEGGQKYLQYIKQTVEEDFSGLHIALDCAHGATSSLAPYLFADLEADISTMGTSPNGMNINDGVGSTHPEVLAELVKEKGADIGLAFDGDGDRLIAVDEKGNIVDGDQIMFICAKYMKETGQLKHNTVVSTVMSNLGFYKALEANGITSDKTAVGDRYVMEEMKRGGYNLGGEQSGHIILLDYITTGDGMLSALQLVNIMKMTKKPLSELAGEMTKFPQLLVNVRVTDKKLALENEKIKEIIRVVEEEMNGDGRILVRPSGTEPLIRVMAEAPTQEVCDAYVHRIVEVVKAEVGAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RIP2_MOMBA
Sequence: MVKCLLLSFLIIAIFIGVPTAKGDVNFDLSTATAKTYTKFIEDFRATLPFSHKVYDIPLLYSTISDSRRFILLDLTSYAYETISVAIDVTNVYVVAYRTRDVSYFFKESPPEAYNILFKGTRKITLPYTGNYENLQTAAHKIRENIDLGLPALSSAITTLFYYNAQSAPSALLVLIQTTAEAARFKYIERHVAKYVATNFKPNLAIISLENQWSALSKQIFLAQNQGGKFRNPVDLIKPTGERFQVTNVDSDVVKGNIKLLLNSRASTADENFITTMTLLGESVVN
What are the official names of this protein?
Ribosome-inactivating protein momordin II, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RS12_BURP6
Sequence: MPTINQLVRKGRASETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DTD_SHEPC
Sequence: MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTTETGQFGADMQVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAVR1_HUMAN
Sequence: MHPQVVILSLILHLADSVAGSVKVGGEAGPSVTLPCHYSGAVTSMCWNRGSCSLFTCQNGIVWTNGTHVTYRKDTRYKLLGDLSRRDVSLTIENTAVSDSGVYCCRVEHRGWFNDMKITVSLEIVPPKVTTTPIVTTVPTVTTVRTSTTVPTTTTVPMTTVPTTTVPTTMSIPTTTTVLTTMTVSTTTSVPTTTSIPTTTSVPVTTTVSTFVPPMPLPRQNHEPVATSPSSPQPAETHPTTLQGAIRREPTSSPLYSYTTDGNDTVTESSDGLWNNNQTQLFLEHSLLTANTTKGIYAGVCISVLVLLALLGVIIAKKYFFKKEVQQLSVSFSSLQIKALQNAVEKEVQAEDNIYIENSLYATD
What is the function of this protein?
(Microbial infection) Plays a positive role in Chikungunya virus cell entry.
What are the official names of this protein?
Hepatitis A virus cellular receptor 1, HAVcr-1, Kidney injury molecule 1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T-cell immunoglobulin mucin receptor 1, TIM, TIM-1, T-cell membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. TIM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HSPQ_SERP5
Sequence: MIASKFGIGQQVRHKLLGYLGVVIDIDPEYSMEQPKADEIAANTDLRFAPWYHVVMEDEEGQPVHTYLAEAQLDGEAQEAHPEQPSLDELAESIRHQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_BACAH
Sequence: MTFEQLIPLIIMAFALGMDAFSVSLGMGMMALKIRQILYIGVTIGIFHIIMPFIGMVLGRFLSEQYGDIAHFAGAILLIGLGFYIVYSSILENEETRTAPIGISLFVFAFGVSIDSFSVGLSLGIYGAQTIITILLFGFVSMLLAWIGLLIGRHAKGMLGTYGEIVGGIILVGFGLYLLFPI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_MYXXD
Sequence: MDDFQKAAARARELHRELAHHNYRYYVLDSPEVSDAQYDKLMRELQDLEAKHPSLQTPDSPTQRVGGAAAEEFGEVVHRAPMISLANIFEDQGLTEFDERIRKLVGLPGIAYVCEPKLDGLAIALRYEKGAFVQGATRGDGTTGEDVTSNLRTIRSLPMSLFPQDDVKVPDVLEVRGEVFIRKKDFQKLNEKREEEGEPLFANPRNAAAGSLRQLDPRMTAARPLSVFLYECVPGEGVPVFKTHIEKLEYLKTLGLPINQYRRAEGLEGVRQAYDASLKGRHELPFEVDGMVVKVDDEDQRKRLGQVSKSPRWAVAYKFPPEEESTEVMDIGIQVGRTGALTPVAHLKPVKVGGVTVARATLHNEDELRRKDVRKGDTVFVRRAGDVIPEIVSVVLSKRPADSAPFEFPKHCPVCDAVATKDEDGAIIRCTGASCPAQLVEKIRHFASRLAMDIEGLGDKLAAQLVSTGRVKAFADLYALTKEDLLTLERMGDKSADNLIASLERSKQTTQRRFLYSLGIRHVGDATAKALAEAFPRSEMLFEASLEDISRVKDVGPIMAQVIHTFFQEPQNQEAIRALLAAGVQPAAPQVATGGPFVGKSVVLTGAMTGMTREQAKEEVERRGGKVAGSVSRKTDFVVAGEDAGSKLKKAQELGVRILDEQAFLQMLQTNA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: BLAI_MYCTO
Sequence: MAKLTRLGDLERAVMDHLWSRTEPQTVRQVHEALSARRDLAYTTVMTVLQRLAKKNLVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVERVGADEADALRRALAELEAGHGNRPPAGAATET
What is the function of this protein?
Transcription regulator that regulates genes involved in antibiotic transport, detoxification and cell wall function.  Also regulates its own transcription.  Binds DNA as a dimer (By similarity).
What are the official names of this protein?
Transcriptional regulator BlaI.
What is the protein family that this protein belongs to?
Belongs to the BlaI transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2534_DEIRA
Sequence: MGRGGRGVGGGRPEGHGASVEGGRTRQTEGMDLISPDPGRWAARFDRHRWRIRLALPQARTEHIGSTAIGTICAKDVVDILVGEVDVTAAAQALVSAGYVIEGERPNHIWLCWPDPQQREAVVHVVIAGGDIWHQRLLFRDFLKRSPAEARAYEALKQRLAAQTDDWGEYTAQKAAFVARILQRAAES
What are the official names of this protein?
UPF0157 protein DR_2534.
What is the protein family that this protein belongs to?
Belongs to the UPF0157 (GrpB) family.
Protein: PUR5_CLOBJ
Sequence: MVSYKEAGVNIEEGYKSVDLIKKHASKTFTKGVLNNLGSFAGMFELPKYKNPVLVSGTDGVGTKLDIAFRMKKYNTVGIDCVAMCINDILCHGAKPLFFLDYIACGKLEAEVAAQLVEGVSNGCIQSECALIGGETAEMPGFYRDGEYDIAGFAVGIAEKDEIIDGSKIEDGDILIGIASSGPHSNGYSLIRKLVEDLHKDFEGNKIGNTLLTPTKIYVKPVMKLLEKYNIKGMAHVTGGGFYENIPRMFKEDFTAVINKKSYPLPNIFSHLISLGIEEDHMYNTFNMGIGFVLCVNEKDGENIIKDLIEMGEKGYKIGYVKKGDKSVELI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_BURCM
Sequence: MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPSKPSRKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RIBBA_BACC7
Sequence: MFHRIEEALEDLKQGKVVIVCDDENRENEGDFIALAEYITPETINFMITHGRGLVCVPITEGYAERLQLEPMVAHNTDSHHTAFTVSIDHVSTTTGISAHERATTIREMLNPASKGADFNRPGHIFPLIAKEGGVLRRAGHTEAAVDLAQLCGAEPAGVICEIINEDGTMARVPDLLQCAKQFDIKMITIEDLIAYRRHHETLVTREVEITLPTDFGTFHAIGYSNSLDSKEHIALVKGDISTGDPVLVRVHSECLTGDVFGSCRCDCGPQLHAALAQIEREGKGVLLYMRQEGRGIGLLNKLRAYKLQEEGFDTVEANEKLGFPADLRDYGIGAQILKDLGLQHLRLLTNNPRKIAGLQGYDLEVIERVPLQMPAKEENKTYLQTKVNKLGHLLNL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: EPMA_SERP5
Sequence: MSETASWQPSAPIANLLKRAAILTEIRRFFADRGVLEVETPTMSQATVTDIHLFPFQTRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQMGRSFRNEEAGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCDSAETLSYQQAFLRHLDIDPLSAEKAQLREAAAKLDLSNIADTEEDRDTLLQLLFTVGVEPHIGRDKPAFVYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDSREQGQRFAQDNRKRAERGLPQHPIDNNLLDALQHGMPECSGVALGVDRLVMLALGAESLSEVLAFPVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RDGC_SHESR
Sequence: MWFKNLTLYRFNKPFSIETEALETALADFTFSPCGSQDVSKFGFSNALGKQGSTLVHSANNRHLICVTKEEKILPGQVIKESLEEKVALIEDEENRKLAKKEKDALKDEIITSLLPRAFSRRSQTRALILPELEMILVDSSSATKAEELLALLRKALGSLPVIPLSFKAPVESNLTQWLKDGSAPLPFEMQDEAELKSAADEGGIVRFKQQDLKEDEVLAHLETGKEVHKLALHFGQSIALLLQSDASVKRLKFSEEFRAGNDELGNEDPMARLDADFALMGSELVALMHALVSALGGLEETQA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.