PharMolix/UniProtQA huggingface dataset:
Protein: ERA_BACSU
Sequence: MTNESFKSGFVSIIGRPNVGKSTFLNRVIGQKIAIMSDKPQTTRNKVQGVLTTGTSQTIFIDTPGIHKPKHKLGDFMMKVAQNTLKEVDLILFMINAEEGYGKGDEFIIEKLQTMSTPVFLIVNKIDKIHPDQLLLLIDEYRKRYPFKEIVPISALEGNNIETLLAQIEAYLPEGPQFYPSDQVTDHPERFIISELIREKVLHLTREEIPHSIAVAIESIKGQDNGSVHVAATIVVERDSQKGIVIGKKGSLLKEVGKRARADIEALLGSRVYLELWVKVQKDWRNKMSQLRDFGFKEDEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity).  Binds both GDP and GTP.  Complements an E. coli era disruption mutant.
What are the official names of this protein?
GTPase Era, Bex protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: GNAS3_MOUSE
Sequence: MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQRAAQRRSFLNAHHRSAAAAAAAQVLPESSESESDHEHEEVEPELARPECLEYDQDDYETETDSETEPESDIESETEIETEPETEPETAPTTEPETEPEDERGPRGATFNQSLTQRLHALKLQSADASPRRAQPTTQEPESASEGEEPQRGPLDQDPRDPEEEPEERKEENRQPRRCKTRRPARRRDQSPESPPRKGPIPIRRH
What are the official names of this protein?
Neuroendocrine secretory protein 55, NESP55.
What is the protein family that this protein belongs to?
Belongs to the NESP55 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Neuroendocrine secretory granules.
Protein: DNAJ_CAMJD
Sequence: MEISYYEILEITQNADKETIKKAYRKMALKYHPDRNQGDKEAEDKFKLVNEAYEVLSNDEKRAIYDRYGKDALKGGGFGSNSSGFGGFEDLGDIFSSFFGESFGSSSRRRKSSNDEKIPSDFIFNLKLSFKEAVFGCKKNIDFTYKCSCKTCNGTGAKDGKLQTCPKCQGRGQVGVSQGFITFAQTCPDCQGSGEKASEKCNDCKGLGYNESKDSVELNIPEGVDTGMKLRVNAKGNILKNNTRGDMYVKIIAAEDDTFIRDDDDIYIEFPVFFTQAILGQSIKVPTIRGEVTLNLPKGAKDGQRFVLEKEGVKDVHSSRIGNQIVQISIKFPTSLNDEQKELLEKLSESFGIKDGMHQEQKGLFEKIANWFKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF32_HUMAN
Sequence: MLKNKGHSSKKDNLAVNAVALQDHILHDLQLRNLSVADHSKTQVQKKENKSLKRDTKAIIDTGLKKTTQCPKLEDSEKEYVLDPKPPPLTLAQKLGLIGPPPPPLSSDEWEKVKQRSLLQGDSVQPCPICKEEFELRPQVLLSCSHVFHKACLQAFEKFTNKKTCPLCRKNQYQTRVIHDGARLFRIKCVTRIQAYWRGCVVRKWYRNLRKTVPPTDAKLRKKFFEKKFTEISHRILCSYNTNIEELFAEIDQCLAINRSVLQQLEEKCGHEITEEEWEKIQVQALRRETHECSICLAPLSAAGGQRVGAGRRSREMALLSCSHVFHHACLLALEEFSVGDRPPFHACPLCRSCYQKKILEC
What is the function of this protein?
May play a role in sperm formation.
What are the official names of this protein?
RING finger protein 32.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_ECOL6
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLQNFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKITPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: RS13_GEMAT
Sequence: MARIAGVDLPREKKVEIGLTYIFGIGRKTAQKILEASGVSSAQRVRDLNDNDLNKLRQEIERNHRVEGALRTEVAMNIKRLMDIGSYRGTRHRRGLPVRGQRTHTNARTKKGPRRAIAGKKKVTK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SCX7_TITPA
Sequence: MKGMILLISCLMLIEVVVECKEGYPLDTLNGCKVGCFFGTNSWCNDKCKSKTAAKGYCAWPSCYCYGFTDDSKIWDLKKNKC
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Tpa7, T-beta* NaTx1.3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZCPW2_MOUSE
Sequence: MGPAPESSEFVHRTWVQCENESCLKWRLLSPAAAAAVNPSEPWYCFMNTDPSYSSCSVSEEDFPEESQFLENGYKFVYSQLPLGSLVLVKLRNWPSWPGILCPDPFKGKYVTYDQDGNVEKYYVEFLGDPHSTAWMSAAFVGHFSLTLEAADCTKKKRWYRSALEEAYQLYRCSAEQRLEVCCLSKPNRAKTDTKAAVVTKKGMQVSKINTEKKRPRVRKRKRDAALKCSVEIFCSDEALSKENMVVSETEGLLKELEKMLQQIQEPTAREDESQGEQLSQCSPESPTGSPFQSYHEEDYIVPDGAGLKAGEYIEIITNNLKKIDALISEF
What is the function of this protein?
Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3 (By similarity).  The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0 (By similarity).
What are the official names of this protein?
Zinc finger CW-type PWWP domain protein 2 homolog.
Protein: HIF1N_MOUSE
Sequence: MAATAAEVAASGSGEAREEAEAPGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMGNFQNFKPRSNREEIKFHEFVEKLQAIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGHKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFRNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
What is the function of this protein?
Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD).  Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator.  Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.  Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins.  Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively.  Negatively regulates NOTCH1 activity, accelerating myogenic differentiation (By similarity).  Positively regulates ASB4 activity, promoting vascular differentiation.
What are the official names of this protein?
Hypoxia-inducible factor 1-alpha inhibitor, Hypoxia-inducible factor asparagine hydroxylase.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
Protein: AGDC_ASPTN
Sequence: MLGSLLLLAPLAGAAVIGSRSNNTEPCPGYKVSNVREGVNSLTADLSLAGKPCNTYGTDLKDLKLLVEYQTERPDERLHVMIYDANEQVYQVPESVVPRVEGRKGARPHSALKFTYEEEPFSFTVTRDDEVLFDTSASNLIFQSQYLNLRTWLPEDPYLYGLGEHTDSLRLPTTNYTRTIWNRDSYGVPQNSNLYGAHPVYYDHRGESGTHGVFLLNSNGMDIRIDKTEDGQQYLEYNTLGGVFDFYFFTGSTPKETSMEYSKIVGLPAMQSYWSFGLHQCRYGYRDVYQVAEVVYNYSKAGIPLETMWTDIDYMNARKVFTLDPERFPLPKMRELVDYLHKHDQKYIVMVDPAVSAVDNEAYEHGVDQGIFLQQQNGSLYKGAVWPGVTVYPDWFHPDIQEYWNSEFSAFFSADDGVDIDGLWIDMNEAANFCTWPCADPEQYAIDNDLPPAPPAVRPSNPRPLPGFPDSFQPSSSKRAVKRAGGSKGAKVGLPGRNLVDPPYKIQNAAGSISNKTINTDIIHAGEGYAEYDTHNLYGTMMSSASRGAMLNRRPDVRPLIITRSTFAGAGSHVGHWLGDNLSQWDQYRISISQIVAFASMFQVPMVGADVCGFGGNTTEELCARWAALGAFYTFYRNHNEIGSTSQEFYQWPTVADSARKAIEIRYKLLDYIYTAFHKQTETGEPFLQPMFYLYPEDENTFANDVQFFYGDALLVSPVLTEGSTSVDAYFPDDIFYDWYTGAPVRGHGAKKTLENIDVTHIPLHVRGGNIIPVRSSGAMTTKELRNKSFELIIAPGLDGTASGSLYLDDGDSLEQKGTAEIKFEYRRGKLSVKGSFGRSAAGVKVQAVKVLGQKAESRMSAFRSTEFELTRPMEISLQ
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Has both alpha- and beta-glucosidase activity (By similarity).
What are the official names of this protein?
Probable alpha/beta-glucosidase agdC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 4OT_PSEUF
Sequence: MPIAQLYIIEGRTDEQKETLIRQVSEAMANSLDAPLERVRVLITEMPKNHFGIGGEPASKVRR
What is the function of this protein?
Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
What are the official names of this protein?
2-hydroxymuconate tautomerase, 4-oxalocrotonate tautomerase, 4-OT.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: RS12_ECOK1
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: APAH_SHESM
Sequence: MAHYFVGDVQGCFAELKRLLAEVDFNPSRDELWAVGDLVARGPDSLATLRYFQSLGDAGKTVLGNHDLHLLALHGKLKRDKPSDNLAPLLNAPDIASLIYWLRQQPLMRELPEHKVIMTHAGVPPQWSLDVLRQESQLVSQALKQGDYLDALISQMYSDTAERWDPSAIGLNRLRFCINALTRMRYLYVDGHLDFDCKQPPEDCNNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDPKLKALDTGCCWGEYLTLWHLEKDQKITQKKLKKG
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: ACEA_KOMXY
Sequence: MGIISHSIVQCGKWQAGPARRQVVFRVHRRCFKMSEALRHLKNGETDLSSLPSGLDSIPRRIHTARGVDDSFSYRHPVLPQVVVLSDAFCVCLAVVACIAWQRIYDTPDELSGALLLANIMAAGAFFLFPKNVPLLDIPDITKVSVQIRYLLPPVAFGEVVFCTVLVMLSWPFGVTVRMGMEWLTFVVAILFVERCVGTYILHTPTMTRRLARKVAIIGSGSEATQMATRINTRMQRMFRLVGTFDDQGGDSDGTVEELVLRAREDHIDAVIICFPPACGQQHVMDVLWRLRGVLADVYVVPSLMTEDCHGWPVERFGPFSLTVLQRRPLSEWDMLEKRAFDLTASVLLLLALAPLLTLVALAIKLDSRGPVLFCQPRQGFNNRYFNVFKFRSMYTDMSDLDAARQTSRTDPRVTRIGRWIRRLSIDELPQLFNVLRGEMSLVGPRPHAPQTRAGGQLLHEAMEEYVARHRVQPGITGWAQINGSRGELVTRDDLCRRVVLDLEYIRAWSIWLDIKIIFLTIKREIFSRNAF
What is the function of this protein?
Involved in the biosynthesis of the exopolysaccharide acetan, a water-soluble polysaccharide involved in production of bacterial cellulose (BC).
What are the official names of this protein?
Undecaprenyl-phosphate glucose phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PP2C1_SCHPO
Sequence: MKGSHPNAGSLLEPLHKLNPFSENSTSGHRKNASDHSADGETRPIAIEMKDSKGNTVPVGNSRPSKASNWLAGLMEDKNQRWRRSMEDTHICLYDFGGNQDDGFVAVYDGHAGIQASDYCQKNLHKVLLEKVRNEPDRLVTDLMDETFVEVNSKIAKATHNDICGCTAAVAFFRYEKNRTRRVLYTANAGDARIVLCRDGKAIRLSYDHKGSDANESRRVTQLGGLMVQNRINGVLAVTRALGDTYLKELVSAHPFTTETRIWNGHDEFFIIACDGLWDVVSDQEAVDFVRNFVSPREAAVRLVEFALKRLSTDNITCIVVNLTRNPGDLDDSGLTADNDSYSNDYY
What is the function of this protein?
It has a serine and threonine phosphatase activity.  Has a specialized role in the heat shock response.  May be responsible for the dephosphorylation of hsp90.  Also has a role in maintaining osmotic stability.
What are the official names of this protein?
Protein phosphatase 2C homolog 1, PP2C-1.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: HPCH_SALPA
Sequence: MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHLANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKNLSGASGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: ASPAT_CORGL
Sequence: MRRYAVMSSVSLQDFDAERIGLFHEDIKRKFDELKSKNLKLDLTRGKPSSEQLDFADELLALPGKGDFKAADGTDVRNYGGLDGIVDIRQIWADLLGVPVEQVLAGDASSLNIMFDVISWSYIFGNNDSVQPWSKEETVKWICPVPGYDRHFSITERFGFEMISVPMNEDGPDMDAVEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTDEFPEVIDIVGLGEAAGNPNRFWAFTSTSKITLAGAGVSFFLTSAENRKWYTGHAGIRGIGPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLEILDSRLAEYGVAQWTVPAGGYFISLDVVPGTASRVAELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEELEVAMDGVATCVLLAAAEHYAN
What are the official names of this protein?
Aspartate aminotransferase, AspAT.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: KATG_GLOVI
Sequence: MDVEAKCPMGGGKVEGRAVLFEMTNRLWWPNHLDLSVLHQNPPAGNPMGEGFNYAAEFESLDLAAVKQDIFALMTESQDWWPADYGHYGPLFIRMAWHAAGTYRIGDGRGGAGAGTQRFAPLNSWPDNANLDKARLLLWPIKEKYGRKLSWGDLLILAGNCALESMGFKTAGFAGGRVDIWEPENDIFWGPEREWLGDERYSSDRDLAHPLAAVQMGLIYVNPEGPNGKPDPMAAAHDIRETFGRMAMNDEETVALIAGGHTFGKCHGAAEPSQYVGAEPEGAGIERQGLGWDNSFGSGRGVHTITSGLEGAWTKNPIQWDNGYFENLFEYEWELTKSPAGAHQWTPKNPEAASTVPDAHDPHKRHAPMMATTDLAMRADPAYEKISRRFYDNPDQLAHAFAEAWYKLTHRDMGPYARLLGPEVPSEPRIWQDPVPASDHPLIDDADIAELKAQILAAGLSIARLVTTAWASASTFRGTDKRGGANGARIRLVPQKDWAVNEPTELATALAKLEAIQQDFNAGQTGGKQVSLADLIVLGGCAAVEQAAKKAGHDITVPFTPGRTDASPDQTDVESFAPLEPKIDGFRNYVGEKSVYSAEEMLVDRAHLLTLSAPEMTVLVGGLRVLGANYGGSKLGVFTERPETLTNDFFVNLLKTSTSMKWEASPDADVFEASDRATGEKKWAGTRVDLIFGSNSQLRALSEAYATADAQQTFVDAFVAAWTKVMNLDRFDLPR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PANB1_PSEF5
Sequence: MSSHTRTQRLSVPQLVAMKGRQKIVSLTAYTSHMARLMDPFVDFILIGDSTAMVGYGRTSTLDMSLAEIIAHTRAVVAGSRLACVIADMPFGSYQESPQQAYRNCAEVMARTGCAALKLEGGRALAPTVEFLVQRGIPVMAHIGLMPQFVNQMGGFKAQGLDSEAARKIEEDARAHLEAGAFSLLLEGVAEPLARRISDFSPMPTIGIGASPACDGQVLVTEDLLGLGGPQVPRFVKQYADAGALISQACERFAAEVREQAFPQLQHCYGVVQEA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRK2C_ARATH
Sequence: MERYEIVKDIGSGNFGVAKLVRDKFSKELFAVKFIERGQKIDEHVQREIMNHRSLIHPNIIRFKEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLENTLLDGSEAPRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYDGKIADVWSCGVTLYVMLVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHSWFLKNLPVEMYEGSLMMNGPSTQTVEEIVWIIEEARKPITVATGLAGAGGSGGSSNGAIGSSSMDLDDLDTDFDDIDTADLLSPL
What is the function of this protein?
Involved in gene regulation and confers tolerance to drought and osmotic stress.
What are the official names of this protein?
Serine/threonine-protein kinase SRK2C, OST1-kinase-like 4, SNF1-related kinase 2.8, SnRK2.8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: TILS_STRP1
Sequence: MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQDKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYAFFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPFLTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLLFQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTAKQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBD_RALSO
Sequence: MTLSAFLPLRRLLQLGLLLVAMATLALPARAADDFLPPEQAFRFSAVQIDGQTVEVKFAIADGYYMYRERLAVAADPATVTFAPLELPPGKVKFDDTFNKDVETYRHALVFRVKAREAASPFSLIVTSQGCADQGVCYPPMKSRFRVEPAAASPAPPAAPLEAAGSSDALGGRIASTLGGGNLGAIAVLFLGLGLLLTFTPCVLPMLPILSAIVVGEHATRMRAAAVSVAYVLGMAVVYTAVGVAAGLAGQGLQAALQNAWVLGAFAALMVVLSLAMFGLYELQLPAAWRHRLTQASNRLSGGQVAGAAVMGALSALIVSPCVTPALAGALAYIAQTGNAMVGGAALFSMSIGMGVPLVLVGVGAGNLLPRAGYWLVVTKAIFGFILLGVALWIVQPVLPAWLAMVAWAVLLIAAAVFLRTFDSLPADAGPLPRLGKVVGVVLALAGAVQLVGVAAGGRDPLQPLAGVMRASAGAQPDARGVVFQRVKSVSEVDEAVRAATATGRPVMLDFYADWCVSCKEMERLTFTDARVRAALADVVLLQADVTADGADDRALLKRFSLFGPPATIFFDAQGNQAPVRVVGFERAETFLASLRRALGTAQAKPST
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DUS3L_RAT
Sequence: MAEVAEVAAESGGGGDSGVGACERGVAPIKAQYRTTKERFHEYLDADKQEGACQETPTEGPAEPEAKRIRLEDGQENGKTEVAVESHERQVPKRARGQNKSRPHMKPAHYDKERLCPSLLQESATPCAFGDRCRFLHDVGRYLETKPADLGPHCVLFNTFGRCPYSMTCRFAGAHLGPEGQNLVQEEVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAEQALSHLTQGPMPTIAPESTVATLTPKHSSCHVQLDNVGGDGARQGSPVPTCGPLTDEDVVRLRPCEKKRLDISGKLYLAPLTTCGNLPFRRICKRFGADVTCGEMAMCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGMNEVLDVPLTVKMRTGVQERVSLAHRLLPELRNWGVALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFGNGDILSFEDANCAMQTGVAGIMVARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWGSDTQGVERTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQQAADWIRISEMLLGPVPPGFVFLPKHKANAYK
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base, in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs).  Mainly modifies the uridine in position 47 (U47) in the D-loop of most cytoplasmic tRNAs.  Also able to mediate the formation of dihydrouridine in some mRNAs, thereby regulating their translation.
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like, mRNA-dihydrouridine synthase DUS3L, tRNA-dihydrouridine synthase 3-like.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
Protein: CASP1_RAPSA
Sequence: MANESTTIEIGESSTMTKRTSHVVVDEKKKGFVAATAGGGYKRGLAIFDFLLRLAAIVTTITASSVMYTAEETLPFFTQFLQFQAGYDDFATFQFFVISIAMVASYLVLSLPFSIVSIIRPLAAAPRLILLISDTVVVTLTTAAAAAAAAIVYLAHNGNPNTNWLPICQQFGDFCQAVSSAVVAASIAVVFFIILIVISAISLKALILYFSSG
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, RsCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: GLMS_LACPL
Sequence: MCGIVGVTGKDSAVSILLNGLEKLEYRGYDSAGIYVNDQDGHDYLVKEKGRIDDLRKEVGEAVHGSTGIGHTRWATHGEPSVANAHPQVSADGRFYLVHNGVIENFEDLKQTYLSDVTFKSQTDTEVIVQLVDRFVTKEGLSTLAAFRKTLGLLGHSSYGFLLMDKEDPDTLYVAKNKSPLLIGVGEGFNVVCSDSLAMLDQTKDFLELHDGEIVVVKPDEIKITNQAGEPVERKPFHVDIDAAQADKGTYPFYMLKEIDEQPNVMRKLSQVYLNDAGDPIINDDLLTALKAADRLYIVAAGTSYHAGLVGAKLFESLANVPTEVHVSSEFAYNQPLLSAHPFFIFLTQSGETADSREVLLNVNDQHFPSLTITNVPNSTLSREATYTLLLHAGPEIAVASTKAYTAQIALQAILAKALGVAVDQPAATAFDVKQQLALVANGMQSLVDEKATFEKIAKSALLNTPNAFYIGRGLDYAVSLETALKLKEISYVQAEGFASGELKHGTIALIEKDTPVIGIITQKNTAGLTRSNLQEVAARGAKTVTIVTDSLAKDGDTVILPTVDERLTALLSVVPGQLLAYYTSLNKGLDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_BACC1
Sequence: MARIAGVDIPRDKRVVISLTYVFGIGRTTAEKILAEAGVSEETRVRDLTEDELGRIRDIIDRIKVEGDLRREVSLNIKRLMEIGSYRGLRHRRGLPVRGQNSKNNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.