PharMolix/UniProtQA huggingface dataset:
Protein: RGSL1_ARATH
Sequence: MEEDDLNPAGKPLYRLYFKGLVTEEKEMLLAGFGVAICGDKDDLLFDLKVSIHDPTITLLEVELIALKSGLNQAVSLGINHISICCDHEYIFELVMGISTPKQESIALLLRDVQGIRKYLTSSIPVMLTQNQSNLAYDFAIEAISSEIIIDIPAQKETCNICLNDDINADQMFSVDKSGHMCCSECVKRHIEVRLLEGSLITCPHYRCNSLLTSVRCGNLLTPKLNKMWEQKTKDELIPVMDRVYCPNPRCSTLMSETELSGLNIGVRRCCVKCGEPFCVKCKVSWHNNLSCDEYKTLHPNPTENDGRLRDLANEKSWRQCSKCKHMIELSSGCISVVCRCGHTFCYQCGADAGDCFHGLGRDDLDLTQCCGSCCCFVFFLVIIAIVVTIILLVRRFS
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (PubMed:24388521).  Negative regulator of the abscisic acid (ABA) signaling pathway which targets PYL4 and PYR1 ABA receptors in plasma membrane to promote their FREE1/FYVE1-dependent trafficking and degradation upon ubiquitynation; this process involves clathrin-mediated endocytosis and trafficking through the ESCRT pathway (PubMed:25330042, PubMed:27495812).  Involved in the maintenance of seed longevity (PubMed:24388521).  May enhance gibberellins responses (PubMed:24388521).
What are the official names of this protein?
E3 ubiquitin-protein ligase RSL1, Protein RING FINGER OF SEED LONGEVITY 1, RING-type E3 ubiquitin transferase RSL1.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Note=Localized transiently in the vacuole when in complex with PYL4 and PYR1.
Protein: NADD_BACFR
Sequence: MAKTKTGIFSGSFNPIHIGHLALANYLCEFEGLDEVWFMVTPHNPFKNQADLWPDELRLQLVQLAIEGYPRFRVSDFEFHLPRPSYTIHTLNRLKQEYPEREFQLIIGSDNWMVFDRWFESERIVSENKILVYPRPGFSVDKSQLPPNVHVADSPIFEISSTFIREALATGKDIRYFLHPAVYKRIIQQTDSIDSSHSCHT
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: UVR8_ARATH
Sequence: MAEDMAADEVTAPPRKVLIISAGASHSVALLSGDIVCSWGRGEDGQLGHGDAEDRPSPTQLSALDGHQIVSVTCGADHTVAYSQSGMEVYSWGWGDFGRLGHGNSSDLFTPLPIKALHGIRIKQIACGDSHCLAVTMEGEVQSWGRNQNGQLGLGDTEDSLVPQKIQAFEGIRIKMVAAGAEHTAAVTEDGDLYGWGWGRYGNLGLGDRTDRLVPERVTSTGGEKMSMVACGWRHTISVSYSGALYTYGWSKYGQLGHGDLEDHLIPHKLEALSNSFISQISGGWRHTMALTSDGKLYGWGWNKFGQVGVGNNLDQCSPVQVRFPDDQKVVQVSCGWRHTLAVTERNNVFAWGRGTNGQLGIGESVDRNFPKIIEALSVDGASGQHIESSNIDPSSGKSWVSPAERYAVVPDETGLTDGSSKGNGGDISVPQTDVKRVRI
What is the function of this protein?
UV-B specific signaling component that acts as UV-B photoreceptor and plays a key role in establishing UV-protective responses in plants.  Upon UV-B irradiation, UVR8 undergoes an immediate switch from homodimer to monomer, accumulates in the nucleus, interacts with the photomorphogenic repressor COP1 and regulates the expression of the transcription factor HY5 by associating with chromatin (through histone H2B binding) in the HY5 promoter region.  UVR8 is involved in controlling aspects of leaf growth and morphogenesis in response to UV-B, is required for normal progression of endocycle and has a regulatory role in stomatal differentiation.  Is required for plant circadian clock response to photomorphogenic UV-B light, partly through the transcriptional activation of responsive clock genes.  Promotes photosynthetic efficiency at elevated levels of UV-B.  Plays a role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway.  The two tryptophans, Trp-285 and Trp-233, serve collectively as the UV-B chromophore.
What are the official names of this protein?
Ultraviolet-B receptor UVR8, Protein UV-B RESISTANCE 8, RCC1 domain-containing protein UVR8.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=UV-B promotes rapid accumulation of UVR8 in the nucleus.
Protein: SELA_ALKMQ
Sequence: MNKGRILSQLPSVDELIKNLEHDKLEKMIPRSVVVEQTRITVDTYRKAILTMDEGSLRDYQIDITSMHDEIKQACESFCSMNLREVINGTGVILHTNLGRSLLSEEIKGQIWEVASGYSTLEIDVTTGKRGSRYNHVVDVLKHLTGAEDALVVNNNAAAVMLVLGTIAKGKEVIVSRGELVEIGGSFRVPDVMEQSGGKLREVGTTNKTHLWDYEGAISDETAALLKVHTSNYRIMGFTESVGLEEIVELGNRYHIPTIEDIGSGVLIDLQKYGLAHEPTVQESVKAGVDIVTFSGDKLLGGPQAGIIVGKRKWIEKMKKNPLTRAIRVDKLTMAALEATLKLYLDEDTAIKHIPTLKMLTENLDTISERASDLFRKLQALDEHLLVRIEEDFSQVGGGSMPLEKLPTKVITLEHTILSAAQMETKLRNFKRPIFTRIRDEKVMMDLRTIREKDFVFIVEALKTVAK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAGAR_ALTAG
Sequence: MFKTKRSLLNSSIAISFAVLGVQAQAETLELQAESFANSGGTYSDGQPNPVTIYNVNGQGAINFVNAGDYVDYNINALGGEYDIEYFVGTGVTSGPNIEVLVDVNGTWQSQGSVAVPYGSWDDFQSLTPSHTVTLPVGTSTVRLLAVGSTWQWNLESFRLTQVSPVEPVGDADNDGVNDNQDLCPNSPSGVTVDNNGCQITGGTDPGGESFVIQMEAFDSTGSDDSRAKGVIIGERGYPQDKHTVVDSVQTTDWVDYSINFPSSANYSVSMLASGQTDHATAVLYLDGTEINEVPVHTGSQADFANFQLAGSVYIASGTHTIRVQAQSSTGEFSWLWFGDALTFTNLDSDGGNGGEATQDADNDGVLDSSDSCPNTPTGEPADVTGCSASQLDDDNDGVSNNVDQCPNTVAGTEVDADGCEVIFADADNDGIEDSQDFCPNTPAGEAVNNSGCGASQLDADNDGVTNNIDQCPNTPAGTQVDASGCETDNGGEPGDSYYHNGQGLLFGRVDGATNFLGEEGYVANPDNYDVTTDLLETDDAIRANSTEVFRGEIYDADGHIAFYEHIDDSVRLYIDGQLVLSNDSWENSSQTTDLNLTPGWHNFELRLGNADGGSGAVSGIGFGIDVDGGTNFVHPSNLSPSMFRASGQVVVDPILPPSGGIYIQLEDFDETGTVGRVASDPNDGFVKGDSNVGWVTNGDWGKYHNVFLEAGTYRAFITVSTPAGGSYGARVDIDGEPFAWGYFDSTGGWDIAAEYELYGGHLVVESTGNHTLHVEAVGGSDWQWSGDLVRLAKVSDSAVKQPRVYNPNEHIVAEIQGPATGLQYLKTPVEIPLANKVLKSDVWYTYPQNRNLVVDGDTPYADFGATGAFWGHPPEHDFYDDTVIMDWAVNVVDDFQSEGFEYTARGEFDWGYGWFTEFTTNPQPHYVQTLDGRNVRMTFMGYLSHDGYNNNWLSNHSPAFVPFMKSQVDQILKANPDKLMFDTQTNSTRSTDMRTFGGDFSPYAMENFRVWLLKKYSNAQLVSMGINDITSFDYGAYLRAQGITHTDWSNAGDTISGNIPMMEDFIYFNRDVWNQKFAEVLEYIRQQRPNIEIGASTHLFESRGYIFNENITFLSGELNLGARTSISELPTNILVHLKGAQAVDKTLAYFPYPWEFDELRIQNAPRFGRGWVAQAYAYGGLFSIPANVWVGGEVFTWSPGADNYRDIYQFVRAQANLLDGYTSYAKAGYVHAMFSSMKAGFIDGGNQVQSSVKILTEDNINFDMLVFGDAGYPVVPRQADFDKFEYIFYDGDLNYLTAEQQAVLDAQGSKVKHIGQRGTIAGLQINVSINGSVSNETVSAVSRIHETDSTAPYVVHLINRPFAGGVTPILNNVEVAIPASYFPQGVTSAKLHLPDGSSSTVAVSTNANGDTVVSVSNLEVWGILELAH
What is the function of this protein?
Alpha-agarase.  Does not hydrolyze agarotetraose, agarohexaose, kappa-carrageenan, iota-carrageenan or lambda-carrageenan.
What are the official names of this protein?
Alpha-agarase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 96 family.
Protein: SLX1_ASPTN
Sequence: MDNVDSDQTKPIPAYYCCYLLRSTVNKRAGLYVGSTPNPPRRLPQHNGLSKGGAKKTATKNRPWEMVLLVEGFMSRTAALQFEWAWQHEDSRHMSKGEPGNTKRRQRPRRSLTANLEKLHSLLQSPCFSRWPLNIRIFASDVYQLWRVWCDRANGTIPEHIRTIPDGNCPHNSPEPETDHPRVGSIDGIQTDYSKIQDYLEKAVFLLDDPNELHCKVCEAQAKPEKELVIVCPQASCFGISHLLCLSARFLKSSNDPNQLVPRSGTCPACSKLVQWPLMMQELSFRTRGGKEVQVILRKKARSDKRKAAAARPAEIDANTASNEPLESTAQAFDRLNENVHQDVLDEDWAEELDCASEDDTNERLKTGSKDQQRVEIVIEDSDEDDLEFL
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANR23_MOUSE
Sequence: MDFISIEQLVSGERVDRKALEFGRGVPDPGGWPSGWTLGPQEAVAREKLKLEEEKRKKLERFNSSRLTLDNLTDLENLVQRRRKKRQRHKVPPREPESGAEPQPQVPLEPVGLEMFLKAAAENQEALIDKYLADGGDPNAHDKLHRTALHWACLKGHRQLVNKLLAAGAAIEVRDLLDRTPVFWACRGGHLDILKRLLNQGAQVNAQDKIWSTPLHVAVRMGHSDCLEHLIECGAHINAQDKEGDTALHEAVRYGHHKATKLLLLYGAKLGVKNVASQTPVQLARDWQRGIRDALQAHVGHPRTRC
What is the function of this protein?
May be involved in the energy metabolism.  Could be a molecular link between myofibrillar stretch-induced signaling pathways and muscle gene expression.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 23, Diabetes-related ankyrin repeat protein.
What are the subcellular locations of this protein?
Nucleus. Note=Sarcomeric I-band and some intercalated disks.
Protein: YIDC_ECO8A
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXC_BLOPB
Sequence: MIKQRTLKRVVQTTGVGLHTGKKVTLTLRPTSANTGIIYRRTDLYPPVDLQVNVKSVGNTVLCTCLINEYGVQIFTVEHLSAAQAGLGIDNIIIELNAPEVPIMDGSASPFVCLLLDAGIEELNSAKKFLRLKQTVRVEDGEKWAELRPFNGFTLDFTIDFNHPAINVDTQHCFFNFSSASFVHNISRARTFGFMRDIKDLQSRGFALGGSFNSAIIIDDYRVLNEDGLRFDDEFVRHKMLDAIGDLFMCGHNLIGSFIAFKSGHTLNNKLLKTVLSCQEAWELATFSNASDLPLVF
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: CYB_SUSBA
Sequence: MTNIRKSHPLMKIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGLYYGSYMFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFVITALAAVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALFMMLILLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAIVRSIPNKLGGVLAVVASILILILMPMLHTSKQRSMMFRPLSQCLFWMLVADLITLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPITSIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PKNG_MYCLE
Sequence: MKREHMDHDTEDVGQAAQRADPPSGTTEGRLQSTQAIFRPNFDDDDDLLHISVPSVDTEPQDRITPATRVLPPIRQLGGGLVEIRRVRDIDPLEALMTNPVVPESKRFCWNCGRPVGRSELEGQEADGAQGAKEGWCPYCGSPYSFLPQLSPGDIVAGQYEVKGCIAHGGLGWVYLAFDHNVNDRPVVLKGLVHSGDAEAQASAVAERQFLAEVVHPQIVQIFNFVEHKDTSGDPVGYIVMEYIGGRSLKRGSKKGNVEKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGCIYGTPGYQAPEIVRTGPTVATDIYTVGRTLAALTLNLRTRNGRYMDGLPEDDPVLTTYDSFARLLHRAINPDPRRRFSSAEEMSAQLMGVLREVVAQDTGVPRAGLSTIFSPSRSTFGVDLLVAHTDVYLDGRLHSEKLTAKDIVTALQVPLVDPTDVAAPVLQATVLSQPVQTLDSLRAARHGMLDAQGIDLAESVELPLMEVRALLDLGDVVKANRKLDDLADRVSCQWRLVWYRAVADLLTGDYASATKHFTEVLNTFPGELAPKLALAATAELAGESDEHKFYRTVWHTNDGVVSAAFGLARFQSAEGDRTGAVCTLDEVPPTSRHFTTARLTSAVTLLSGRSTNEITEQQIRDAARRVETLPPTEPRVLQIRALVLGCAMDWLADNQASANHILGFPFTKHGLRLGVEASLRSLARVAPTQRHRYTLVDMANKVRPTSTL
What are the official names of this protein?
Serine/threonine-protein kinase PknG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NAGS_HUMAN
Sequence: MATALMAVVLRAAAVAPRLRGRGGTGGARRLSCGARRRAARGTSPGRRLSTAWSQPQPPPEEYAGADDVSQSPVAEEPSWVPSPRPPVPHESPEPPSGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCHHSADKPFAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQLAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGGIVSVETDLLQWCLESGSIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLRDSSHKVLSNVNLPADLDLVCNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGTLFKNAERMLRVRSLDKLDQGRLVDLVNASFGKKLRDDYLASLRPRLHSIYVSEGYNAAAILTMEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWYFKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFHKPASDPGS
What is the function of this protein?
Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity.
What are the official names of this protein?
N-acetylglutamate synthase, mitochondrial, Amino-acid acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RHBL1_TOXGO
Sequence: MARVRTLADLRTEDEADEHTPLYNAETGSRDSDSTSSGGAAPRSMPIRFLELLFPHFSLKSVVLAISIVDWIFYIVTVCLDTELPLIPAANILVHFGANYPPLIKQGQVWRLLLPVFLHANFFHVFFNVFFQLRMGFTIERRYGLLKFTGLYFASAIYGNLLSATAFFCNSLKVGASTAGFGLIGIQICEMALTWHRMRHRDRMLTNMVSFVLLMVLLMFTLNGGSIDQMGHLGGLLCGFSIGMLYNKELNDKPVWYPWASAAAIGILLALPAACFPILYAVDRHCHRDLSYI
What is the function of this protein?
Serine protease involved in intramembrane proteolysis and the subsequent release of polypeptides from their membrane anchors.  Has no detectable activity towards MIC2.
What are the official names of this protein?
Rhomboid-like protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, microneme membrane; Multi-pass membrane protein. Note=Detected in micronemes in intracellular and extracellular tachyzoites, together with MIC2.
Protein: ACP_METSB
Sequence: MSDVAERVKKIVIEHLGVDADKVVDNANFIEDLGADSLDTVELVMAFEEEFSVEIPDDAAETIVTVGDAVNFLEKATAA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_CUPPJ
Sequence: MIKQALLSVSDKTGIVEFARELNALGVTLLSTGGTAKLLADSGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMAALAEHDIPTIDLLVVNLYPFQQTVAKDDCTLPDAIENIDIGGPTMLRSAAKNHRDVTVIVDPVDYAVVLDEMRANGNKVGYDTNFRLATKVFAHTAQYDGAITNYLTSLGADKSHQARSAYPQTLNLAFEKVQEMRYGENPHQSAAFYRDLKAVDGALANYVQLQGKELSYNNIADADAAWECVKSFAVTTPACVIIKHANPCGVAVGANALEAYDKAFKTDSTSAFGGIIAFNVELDETAAQAVAKQFVEVLIAPSFSAAARAVFASKQNVRLLEIPLGKGINQYDLKRVGGGLLVQSPDAKNVQPTELRVVTRRHPTPKEMDDLMFAWRVAKFVKSNAIVFCGGGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVDAGATCVIQPGGSMRDDEVIAAADDRGIAMVLTGTRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: OMP2A_BRUC2
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYTGSDRKGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVAAGSYRTGKIAYTFTGGNGFSAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGAVAYDPVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIATEKATFNLQAAHDDWGKTAVTANVAYQLVPGFTITPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2a.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SYH_ECOBW
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_STAAS
Sequence: MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEMNPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIENTVNRFKDFFNN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL35_FRAP2
Sequence: MPKLKTKSGAAKRFKKTGKGGFKHRCANRAHINTKMTTKRKRHLRGMNQVAKVDTASLVQQMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MNMC_MANSM
Sequence: MLKVTTAHIHFNRDNTPVSEQFDDIYFSTADGLEESRYVFQEGNNLWRRWLQFGENHFVIAETGFGTGLNFLAVTALFREFRTQYPDSPLKRLFFISFEKYPMSCADLRSAHQAYPQFNSLAEQLRQNWLQPIVGCYRFHFEETVLDLWFGDIADNLPQLGDYMVNKIDAWFLDGFAPSKNPEMWNENLYKQMFRYTKPAGTFATFTAASAVKKGLESAGFSLQKRKGFGKKRECLQGFKPLNAEQNPAVHTPWLLSRSATLSENTDIAIIGGGISSLFSAISLLQRGANVTLYCEDEQPALNASGNKQGAFYPQLSDDDIHNIRFYIHAFAYGQQQLRWAIQQGIEFEHEFCGVALCAYDEKSAVKLAKISDYDWDTSLYQPLNQQELSEKAGLPLPCGGGFIPQGAWLAPRQFVQNGFAFAQKCGLKLKTFEKITALSQSEKGWILHNDKNEQFHHETVIIANGHKLKQFTQTARIPVYSVRGQVSQIPTSSQLLKLKSVLCYDGYLTPADQAKQFHCIGASHVRDCEDRDFSLQEQQENQAKIQLNIAEDWTKEVNTADNLARTGIRCAVRDRIPLVGNVPDFERQADEYRNIFNLRRRKQFIPQAAVFENLYLVGALGSRGLTSAPLLGEILASMIYGEPIPLSEDILHCLNPNRSWMRKLLKGTPVK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_RUEST
Sequence: MTHNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCKIDEIDFAQIDLCFCALPHKTSQEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAALEQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRPLIAAGVIDLDEIILDMKCAVSGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNRGILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAGRAIVIVALDNLTKGSSGQALQNANLMLGEDETAGLMMAPLFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAT_TRIEI
Sequence: MNQHLNGIPAHGGHLINRIATPAERQEFIEKAESLPKIQLDKRALSDLEMIAIGGFSPLNGFMDKDDYESVVVDMRLKNGLPWSIPVTLSVSEEVADSIKEGSWVGLSSPEGEFAGVLELTQKFHYNKAHEAINVYSTQEIKHPGVKVLYDAGPVNLAGPVWLLERHPHPLFPKYQIDPAESRKLFQEKNWKTIVGFQTRNPIHRAHEYIQKCALEVVDGLFLHPLVGATKSDDIPADVRMRCYEIMLEKYFPENRVMMAINPSAMRYAGPREAIFHALVRKNYGCTHFIVGRDHAGVGDYYGTYDAQYIFDEFEPRELDIVPMKFEHAFYCTRTQGMATSKTSPSTGEERIHLSGTKVREMLRRGELPPPEFSRPEVAAELAKAMKI
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: Y1092_BRUSU
Sequence: MTALILKRVAQAIPVMLIVAILTFLLMKLLPGDPAILIAGDGASPETVERIRVELGLDQPTVVQLGQWLWNLFHFDLGRSFLLSQPVSQAIAERLPVTISLALLAFAITIPVGIIMGVVAAYLRDSWFDMGVMSLALLGVSVPSFWLAILAVILFSVTLGWFPSAGYVPFLDSPLGWLRSLILPASILALFQIGYLARMTRSEMLEVMDQDYIRTARSKGVSEYSVLSTHAFRNALVSVLTVSGYIFSLLIGGSVVIEQIFALPGLGRLLVQAILARDLPVVQGTMLFLGFLFVAINVLVDILYTIADPRVHYD
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative peptide transport system permease protein BRA1092/BS1330_II1084.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIG_COREF
Sequence: MKSSVEQLSDTRVKITVEVPFEELKPELDQAYAALAQQVQIPGFRKGKAPRQLIDARFGRGPVLEQVVNDMLPTRYGQAIEENDIKAIGQPDVEITKIEDNEVVEFTAEVDVRPEITLPDFSAINVEVPAVTVDDAAVDEELESLRARFSTLKDHNHKLKKGEFVTLNLSASVDGEKVEEATTEGLSYEIGSGDLIDGLDEALLGQKKDDTVEFTTELANGDYQGKEAVVTAEITATKQRELPALDDEFAQLASEFDTMEELRESTKTQVETRLKNEQAANIRDEVLKAALESSDFALPNSIVEEQAHSQLHQLLGELAHDDAALNSVLESQGTTREEFEKQNREDAEKAVRTQLFLDVLAETEEPEVSQQELTDHILFTAQSYGMDPNQFIGQLQQSGQIANLFADVRRGKALAQAICRVNVKDSEGNEIDPKDYFGEEEVAEDSNDEAADQE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.