PharMolix/UniProtQA huggingface dataset:
Protein: Y3518_ARATH
Sequence: MTSMYYNHDHLTASGKNMWSNFYVLVDTAVMLYEEEKQRRKIVSEEEEETQKRIFCLFPRKTRSSLVKRQQKLSGFLTSASSSLIDLNQFPSDSEIEDPLNHHQLLSSSCFIAADFETLQNPSSEPCSSLVLFDCKTAGSEKTETKDPPNPNFPCPLSLCLTENKNRKRRAVEQRKRTGGVKKAKVAPFSQTARETPEWLVNVMRDMKEAKDAKLIFEKTLFVTDVNPTQNRLSMPFNNLLRNDFLTSVESRIIDKDIKNDKKIGVGAILVDQRCKKWGVMLKRWEMKKESGKGSWNYNLICGWNDIVEANGLKEGDNISLWSFRSCGILCFAMEQRSPSLALCLC
What are the official names of this protein?
B3 domain-containing protein At3g25182.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_SHEFN
Sequence: MHNAPESVLNALVPMVVEQTAKGERSYDIYSRLLKERVIFLVGQVEEHMANLIVAQLLFLESESPDKDIYLYINSPGGSVTAGMAIYDTMQFIKPNVSTVCMGQAASMGAFLLAGGAKGKRHCLPNSRVMIHQPLGGFQGQASDIAIHAKEILGIKNKLNQMLAEHTGQPLDIIERDTDRDNFMSATQAVEYGIVDSLLTSRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_STRPI
Sequence: MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQMLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVAHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVTGDGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_MIMIV
Sequence: MQSNINICTLSIFIIESMTTRIGRHINISKGFVSAPEYAKNIGCSVFQIFLGAPQQILSKARQKDELIEFGKQLIKHDLIMVVHGSYTINLCHPPGSKKFETSIKSLVKDLNATNLIGDRCLGVIIHMGKNISENKLTVDQAIDNYVTGIKTALSQTPDNTTIVLETGASQGSEVASHIDGLAQIYWCLNDAERERVYFCIDTCHIWATGYDISSPTGVKKFFKEFDKKIGVEKISCIHFNDSKTGLESKVDRHADLCYGEIGSNGLKAIAKFAKEYKIHLIMETPLDAINPETNQEISYNEEYNKVKSWLK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues (By similarity).
What are the official names of this protein?
Putative endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RDH16_RAT
Sequence: MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTSDRLETVILDVTKTESIVAATQWVKERVGNTGLWGLVNNAGISGHLGPNEWMNKQNIASVLDVNLLGMIEVTLSTVPLVRKARGRVVNVASIAGRLSFCGGGYCISKYGVEAFSDSLRRELSYFGVKVAIVEPGFFRTDVTNGVTLSSNFQMLWDQTSSEVREVYGENYLASYLKMLNGLDQRCNKDLSLVTDCMEHALTSCHPRTRYSAGWDAKFFYLPMSYLPTFLVDALFYWTSPKPEKAL
What is the function of this protein?
Oxidoreductase with a preference for NAD.  Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes (PubMed:7499345).  Has higher activity towards CRBP-bound retinol than with free retinol (By similarity).  Oxidizes 3-alpha-hydroxysteroids.  Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione.  Can also catalyze the reverse reaction (By similarity).
What are the official names of this protein?
Retinol dehydrogenase 16, 29 kDa protein, Retinol dehydrogenase 2, Retinol dehydrogenase type 1, Retinol dehydrogenase type II, RODH II.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane. Endoplasmic reticulum membrane; Single- pass membrane protein.
Protein: ACCA_STRPZ
Sequence: MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METC4
Sequence: MSNRMWGGRFASGPAEIMEEINASIGFDRRLASQDIRGSLAHVAMLGSQGILPAEDVAAIEAGLKSVEAEIARGEFVFRRELEDIHMAVESRLTEIVGPAAGRLHTARSRNDQVATDMRLWVRDTLDALDAQVADLQRALAETAVKHAGTVMPGFTHLQSAQPVTFGHHCLAYVEMLARDRGRFRDARARLNECPLGAAALAGTSFPIDRHATAAALGFDRPTANSLDSVADRDFALESLSAASICAVHLSRFAEELVVWTSAQFGFVRLSDGFTTGSSIMPQKRNPDAAELVRAKAGRIIGALTGLLIVMKGLPLAYSKDMQEDKEGTFDALQSLSLCLAAMAGMVRDLEPVAETLKRAAGSGYATATDLADWLVRELNMPFRQAHHVTGRVVAAASERGIGLEELSLQDMQAVEAGITDAVFAVLGVENSVASRTSYGGTAPDNVRRQAEGWLEKLGPVEK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3794_SERP5
Sequence: MYDNLKSLGINQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVADNAGQGYKEIHEINPNLRYVIDELDQLCQRDQVEVDLKRKILDDLRHLEGVVSHKIAEIESDLEKLTRGK
What are the official names of this protein?
UPF0325 protein Spro_3794.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: RECA_SYNP2
Sequence: MSAISNNPDKEKALNLVLNQIERNFGKGAIMRLGDAAQMKVATIPSGALTLDQAMGGGFPRGRIVEIYGPESSGKTTVALHAIAEVQKAGGVAAFIDAEHALDPTYSAALGVDIENLLVAQPDNGESALEIADQLVRSAAVDLIVIDSVAALVPRAEIEGEMGDVQVGLQARLMSKALRKIAGNMGRSGCTVIFLNQLRQKIGISYGNPEVTTGGTALKFYASVRLDIRRIQTLKKGSEGEFGIRAKVKVAKNKVAPPFRIAEFDIIFGKGISRVGCMLDLAEQTGVITRKGAWYSYEGDNIAQGRDNAVKYLEENPDVAAIVTQKVRENLDMSSMGFGDEHHTTEEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_HELPY
Sequence: MKLKSFGVFGNPIKHSKSPLIHNACFLTFQKELRFLGHYHPILLPLESHIKSEFLHLGLSGANVTLPFKERAFQVCDKIKGIALECGAVNTLVLENDELVGYNTDALGFYLSLKQKNYQNALILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFFQRLGCDCFMEPPKSAFDLIINATSASLHNELPLNKEVLKGYFKEGKLAYDLAYGFLTPFLSLAKELKTPFQDGKDMLIYQAALSFEKFSASQIPYSKAFEVMRSVF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SAK_STAAU
Sequence: MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
What is the function of this protein?
Potent plasminogen activator that converts plasminogen into plasmin.  It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules.
What are the official names of this protein?
Staphylokinase, Neutral proteinase, Protease III, SakSTAR.
What is the protein family that this protein belongs to?
Belongs to the staphylokinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFJP_ECOLI
Sequence: MKNFEVLQPLQNSLSGLPLWVSERILQQINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSPVSDVAACTRDPLRFRLQIGEHFMTIVDLPGVGESGVRDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQVIGEAYRHKMLFVISQSDKAEPTSGGNILSTEQKQNISRKICLLHELFQPVHPVCAVSVRLQWGLRVMAERMIKCLPREASSPVVALLQHPFRTTVAREQARDDFGETVGAILDTVSTFPLIPAPVRTIIQAVRSSVVSVARAVWDFFF
What are the official names of this protein?
Uncharacterized protein YfjP.
What is the protein family that this protein belongs to?
To E.coli YkfA and YeeP.
Protein: UPPP_ACIBS
Sequence: MENFEVIKALFLGFVEGLTEFLPISSTGHLILFGHIIDFHSDGGRVFEVVIQLGAILAVCWLYRQKIINLIKGFFSGDVESRHFAISVLIAFFPAVIIGVLAVDFIKSVLFSPIVVAIALIVGALIIFWVESKQFEHKTDDATKITFKQALLVGLAQCVAMIPGTSRSGATIVGGMFAGLSRKAATEFSFFLAMPTMLGAATFDLIKNADVLTSDNMVNIGVGFVAAFIAALLVVKALVLFVERHTLRVFAWYRIVLGVIILIAAMFFNLSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHDF2_HUMAN
Sequence: MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPEGFQNRRLKKSQPRTWAAHTTACPPSFLPKRKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRRKRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH
What is the function of this protein?
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation.  Does not exhibit any protease activity on its own.
What are the official names of this protein?
Inactive rhomboid protein 2, iRhom2, Rhomboid 5 homolog 2, Rhomboid family member 2, Rhomboid veinlet-like protein 5, Rhomboid veinlet-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
Protein: HEMW_SYNY3
Sequence: MNTGTYLMPTAAYIHIPFCRQRCFYCDFPIAVTGFQSLTLDGWVGEYVEAVCREIAGQQHQGQPLQTVFFGGGTPSLLPITGLEKILLAVDQYLGIAPDAEISIEIDPGTFDQVQLQGYKNLGINRFSLGVQAFQDNLLALCGRHHRRRDIDQALTAIAKENIENWSLDLITGLPEQTAADWHSSLTLALAAGPKHISCYDLVLEPQTVFDKWEQRGKLAVPPPERSADFYRHGQEVLTQAGFHHYEISNYGRPGHQCRHNQIYWRNLPYYGLGMGATSYIDGKRFGRPRTRNGYYQWLESWLNQGCPIPGERVSPLENLLESLMLGLRLTAGVTWAQLPSVNQTEKAKILATLTSFGDRRWLEFYGEDNQMLAPNQTTTETVQRFCFTDPEGILYSNQILSALFAALEEDF
What is the function of this protein?
Probably acts as a heme chaperone, transferring heme to an unknown acceptor.  Binds one molecule of heme per monomer, possibly covalently (By similarity).  Binds 1 [2Fe-2S] cluster.  Although this protein has sequence motifs typically found in proteins binding the [4Fe-4S]-AdoMet radical-SAM cluster and S-adenosylmethionine, spectroscopic evidence suggests that a [2Fe-2S] cluster is present; S-adenosylmethionine was not detected.  Has no detectable coproporphyrinogen-III oxidase activity (PubMed:20194361).
What are the official names of this protein?
Heme chaperone HemW, Oxygen-independent coproporphyrinogen-III oxidase-like protein sll1917.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C6A18_DROME
Sequence: MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 6a18, CYPVIA18.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: PANC_SULSY
Sequence: MEVITNPGQMQTLMLSLKKQGKKIGFVPTMGYLHEGHLSLIRCSKKENDITVVSIFVNPIQFGANEDFGRYPRDFERDKSLCEKENVDYIFYPSYEEMYPDGFQTYVEVAELSKGLCGDFRPGHFKGVATVVAKLFNIVCPDNVYFGKKDFQQLKVIQRMVKDLNFPVNVVGCPVVREPDGLAMSSRNKYLSDEERESALNISKALFEAKRMFEDGITDPNLIKERVRQIISQAKHLKEIQYVEIVDSNTLKPVDKVKKSDVLAVAVYIGNTRLIDNIEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_YERPY
Sequence: MSWFTPELIEILISVLKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWVPRFSDRAIFTLAPVIAFTSLLLSFAIVPVSPTWAVADLNIGILFFLMMAGLAVYAVLFAGWASNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQVGSFNMQDIVNSQEHVWNVIPQFFGFLTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALIVTLFFGGWQGPFLPPFIWFALKTAFFMVMFILIRASLPRPRYDQVMSFGWKVCLPLTLLNLLATAAVILYNAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_AERHH
Sequence: MDTQTLNFNKVHFVTSAPDIRHLPNDGGVEIAFAGRSNAGKSSALNTLTKHKNLARTSKTPGRTQLINLFELEPGKRLVDLPGYGYAQVPLEMKLKWQKSLAEYLQRRESLKGLVILMDIRHPLKDTDMNMLEWSSHRKLPVMLLLTKADKLSPGPRNNQVIKVRQAVAELGPQIQVEAFSSLTQIGVEKLAQTLTGWYLAGADDMTDGEQAPLEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS7_ARTPT
Sequence: MSRRRVVQKRPVPPDSRYNSRLVSMMVRRIMRHGKKSVAHNIVYDALATIEERTGSDPLELFEKAVRNATPLVEVKARRVGGATYQVPMEVRSERGTTLALRWLIHFSRTRSGRSMASRLASELMDAANETGSAVRKREETHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CINAL_CHLL2
Sequence: MIAEIVSIGDELLKGGKVNTNASFIAAALGGIGVPVIRIVACSDDEDQIITVLSESLSRTDLVLVTGGLGPTRDDRTKKAVMRLLQRSVVESEEAFHMLASWFTARGRMLPDTLRDQATIIEGSVLVPNSVGTAAGMIISCGERFGNSSLVLMPGVPSEMQEMMRKTVIPFFAGQSTTAILHTPVKTVGIGESALADLIAAEEDALPEGTTLAYLPHTAGVDLVVSTVGSITEVVERDNRRVVDAILSRAGRFIYATGDTTLEETVGRMLAENSLSIAVAESCTGGLLASRLTDVPGSSAYFQQGIISYSNDAKVQLLGVDRMTLEAFGAVSEPVAKEMARGVLERSGADIAVSTTGIAGPSGGSGDKPVGTLCIGIAGKKSDGSIAFRTGTFRMAGTRAQNKQRFSEAALREAWTYLQEVVGPVRVAG
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RL30_STAEQ
Sequence: MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLLTIEEEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: C5I3_DERAN
Sequence: MAALNGLVLLLLTISAMFISECYSSGESQSIQRKGQCEEVICHRKLNHLGERVTSGCPTGCLCVIREPDNVDNANGTCYALMSSTTTTTTTPDGTTTSEEEE
What is the function of this protein?
Complement inhibitor (PubMed:27018802).  Prevents complement-mediated C5 activation by binding to C5 (PubMed:27018802).  Binds C5 at a different binding site than the other tick complement inbibitors OmCI and CirpT1, and the drug eculizumab (PubMed:27018802, PubMed:31871188).  Inhibits complement in human and guinea pig but not in other species tested (rabbit, rat, mouse, and pig) (PubMed:27018802).
What are the official names of this protein?
Complement inhibitor RaCI3.
What is the protein family that this protein belongs to?
Belongs to the RaCI family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEXA_GEOTN
Sequence: MTKLSKRQQQILEFIKQEVKTKGYPPSVREIGEAVGLASSSTVHGHLARLESKGYIRRDPTKPRAIEILDSDLTKEREKEEVISVPMIGKVTAGQPITAVENIEDYFPLPKRLAAGEKQLFMLEVMGDSMIEAGILDGDYVIVRQQSSANNGDIVVAMTEENEATVKRFFKEKDHIRLQPENVHLEPIIVRDCTILGKVIGVYRLIN
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RS20_BURVG
Sequence: MANSAQARKRARQAAKANSHNSALRSKFRTAIKSVRKAVEAGDQAKAAELFKAAVKTIDTIADKKIVHKNKAARSKSRLAAAVKGLQAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CILA_ECOLI
Sequence: MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDRKLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSDCHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNIDVAFLGVPSCDEFGNANGYTGKACCGSLGYAIVDADNAKQVVMLTEELLPYPHNPASIEQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQTGTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAAQSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRGASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPARPELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQVKE
What is the function of this protein?
Represents a citrate:acetyl-ACP transferase.
What are the official names of this protein?
Citrate lyase alpha chain, Citrase alpha chain, Citrate (pro-3S)-lyase alpha chain, Citrate CoA-transferase subunit.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_BRAHW
Sequence: MEKNYMTIPYVIEQTSRGERSYDIYSRLLKDRIIFLGGEINDDVANVVIAQLLFLESADPEKDISLYINSPGGVVTAALGMYDTMQYVKPDVATLCVGQAASAGALLLAGGAKGKRFATANSRIMIHQPSGGSRGMVTDMEIQLKETIRLKSILNNIMANHTGQDIKKLEADMDRDYFMSAEEAKDYGIIDKVFSSRE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFE_KLEP3
Sequence: MSEVKDVIVQGLWKNNSALVQLLGMCPLLAVTSTATNALGLGLATTLVLTLTNLTISSLRRWTPAEIRIPIYVMIIASVVSVVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREILGNGTLFDGADSLLGSWAKVLRIEVFHTDTPFLLAMLPPGAFIGLGMMLAVKYLIDERSKQRKARAARAVSVAPADVTGKA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DDL_SACD2
Sequence: MTTTYVKKFDGNTAALGRTLVLFGGTSSEREVSLRSGAAVLQALQAGGVDAHGLDVQADAIAKIEAFAPDRVFIALHGPGGEDGKMQAVLDWLAIPYTGSDHAASALAMDKLKTKQVWQSVGLVTPEYASLVENSDWQAVLDSLGGQGFVKPAHEGSSIGMSVVSTAQELKAAYEKAAHYDAKVLVERRIVGREFTVAVLNGVALPAIGLKTDHVFYDYDAKYVSNTTQYLCPCGLTQEKEAELQSIAQQAFAAVGCKGWGRVDFMQDEAGNFYLLEVNTVPGMTDHSLVPMAARQSGIEFNELVLEILAQTLV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_THEP1
Sequence: MRVGIKVLGCPKNEADCEVLAGVLREGGHEIVFDVKDADVVVLDTCAFIEDAKRESIDEIFSFVDAKDQYGYKLVVKGCLVQRYYEELKKEVPEVDQWIGVADPEEIANAIENGTDLVPDQPETVYRYRKRIDLEERPYAYVKISDGCDRGCTFCSIPSFKGSLRSRSIEDITREVEDLLKEGKKEIILVAQDTTSYGIDLYRKQALPDLLRRLNSLNGEFWIRVMYLHPDHLTEEIISAMLELDKVVKYFDVPVQHGSDKILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSIIVGFPGETEEDFEELKQFVEEIQFDKLGAFVYSDEEGTVAFNLKEKVDPEMAKRRQEELLLLQAEISNSRLDRFVGKKLKFLVEGKEGKFLVGRTWTEAPEVDGVVFVRGKGKIGDFLEVVIKEHDEYDMWGSVI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.