PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_PSYCK
Sequence: MTDPIAPLTSKDINTAKSAANEDAIVAQMRTFIDALKKHNYAYYVLDNPILEDSEYDQLRRSLLELEEEYPDLIQPDSPINQVGDMPLSAFTQVTHDIPMLSLGNVFEYDDLRDFMRRVNDRLSVAQQSPEYEMELKLDGLAVSLKYAYGKFVQAVTRGDGQTGEDITQNAKTIRNLPLWIPAASDIELLEVRGEVLMPKAGFERLNRLAEEKGDKTFANPRNAAAGSLRQLDPAIAASRPLAFYCYSVNQGLPEHIKTQSAALAWLKTIGFTVSAVEVVQNPREAQAYYESVKETRGDLPFEIDGMVIKVNSLALQQQLGFLSREPRWATAYKFPAETVMTRLHAIEWQVGRTGAITPVGKLEPVKVGGVTVSNVTLHNFGEIQRLDVRAGDMVSVHRAGDVIPKVTRVWTDQRPENSEPVKLPSTCPVCDSPVVLPKDEALARCTGGLFCPAQQVEALIHFVSRRAMDIDGLGASWLISFFEHGLVKTVADIYQLHNHQEELITLEKLGEKSVQNILSAIEASKQTTLARFIYALGIRGVGETTAQNLAQQFGDLDALMSASIEKLLLTPDVGAITAELTYKFFRAPHNIEVINALREAGVHWDKVEQVASEGLPLDGQTWVITGALDSMARDEAKAKLQALGAKVSGSISAKTTALLAGDKAGSKMAKAEKLGVKVVGEEEFLVLVGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DBP10_ASPFU
Sequence: MPHRAASPAVSENEFDITGALFQNDSDSDNEQPSAKSKRQPPKKAFIAEQQTSANRKASNLKGRTVKKGGGFQAMGLSANLLKAIARKGFSVPTPIQRKTIPVIMDDQDVVGMARTGSGKTAAFVIPMIEKLKSHSTKVGARGLVLSPSRELALQTLKVVKELGRGTDLKSVLLVGGDSLEEQFAMIAGNPDIIIATPGRFLHLKVEMNLDLSSIRYVVFDEADRLFEMGFAAQLTEILHGLPANRQTLLFSATLPKSLVEFARAGLQEPTLVRLDTESKISPDLQNAFFSVKSSEKEGALLYILHEVIKMPTGPTEVSQQRKEEDASAKNLKNKKRKRAEMEKAVNTRESPTKHSTIVFAATKHHVDYLYSLLCEAGFAVSYVYGSLDQTARKIQVQNFRTGMTNILVVTDVAARGIDIPILANVINYDFPSQPKIFVHRVGRTARAGRKGWSYSLVRDADAPYLLDLQLFLGRRLVVGREFGDQVNFAEDVVTGSLPRDGLSQSCEWVTKVLDDNADLAAQRTVAAKGEKLYMRTRNAASLESAKRSKQVVSSDNWTSVHPLFQDETSNLEAEREKMLARIGGYRPPETIFEVNNRRMGKHENVDALDTIKRVRSTLESKKKPFSDEDDDVPTGVADNMSMASDSELEVTFSSYSKSKDNKAKKASAASFQNPEYFMSYTPNNTSLAEDRAYGVHSGTNSNFAQASRSATMDLAGDDGGRGFGEARTLMRWDKRHKKYVARQNDEDGSKGTRLVRGESGAKIAASFRSGRFDAWKRENRLGRLPRVAISGKRFRHRKEQAPKKADPLRGDYEKMKKKAELAKERAMSKAGGAAPRGKSELKSTDDIRIARKLKQKRREKNARPSRKK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AROC_RHILO
Sequence: MSHNTFGHLFRVTTWGESHGAALGCVVDGCPPGIRFTRDEIQAELDKRRPGQSRFVTQRREPDEVKVLSGFVLDEDGETMITTGTPVSMLIENVDQRSKDYGEIARQYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGALARKVVPGMVVRGALVSMGEKSIDRANWNWNFIGDAENPFFTPDPASVPVFTQYLDGIRKAGSSVGAVIEIVADGVPPGLGAPIYAKLDQDIASGLMSINAVKGVEIGNGFEAARITGEQNADEMRIGNDGKPVFLSNNAGGILGGISTGQAIVARFAVKPTSSILTPRKSIDKDGNDVEVMTKGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGKGIGSRE
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ILVX_MYCTU
Sequence: MNGAQALINTLVDGGVDVCFANPGTSEMHFVAALDAVPRMRGMLTLFEGVATGAADGYARIAGRPAAVLLHLGPGLGNGLANLHNARRARVPMVVVVGDHATYHKKYDAPLESDIDAVAGTVSGWVRRTEAAADVGADAEAAIAASRSGSQIATLILPADVCWSDGAHAAAGVPAQAAAAPVDVGPVAGVLRSGEPAMMLIGGDATRGPGLTAAARIVQATGARWLCETFPTCLERGAGIPAVERLAYFAEGAAAQLDGVKHLVLAGARSPVSFFAYPGMPSDLVPAGCEVHVLAEPGGAADALAALADEVAPGTVAPVAGASRPQLPTGDLTSVSAADVVGALLPERAIVVDESNTCGVLLPQATAGAPAHDWLTLTGGAIGYGIPAAVGAAVAAPDRPVLCLESDGSAMYTISGLWSQARENLDVTTVIYNNGAYDILRIELQRVGAGSDPGPKALDLLDISRPTMDFVKIAEGMGVPARRVTTCEEFADALRAAFAEPGPHLIDVVVPSLVG
What is the function of this protein?
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
What are the official names of this protein?
Putative acetolactate synthase large subunit IlvX, ALS, Acetohydroxy-acid synthase large subunit, AHAS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: ATF7_MOUSE
Sequence: MGDDRPFVCSAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKASDDDEKKGAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTTKPVVISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQIGSPTGSLPLVMHLANGQTMPMLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNNSGSISPSGHPMPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQNQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLGK
What is the function of this protein?
Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation (PubMed:29490055).  In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as Htr5b, STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes (PubMed:19893493, PubMed:31294895, PubMed:30826729).  Phosphorylation of ATF7 disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation (PubMed:19893493).  In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening (PubMed:29490055).  Also plays a role in maintaining epithelial regenerative capacity and protecting against cell death during intestinal epithelial damage and repair (PubMed:31958521).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-7, cAMP-dependent transcription factor ATF-7, Activating transcription factor 7, Transcription factor ATF-A.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Chromosome, telomere. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear peiphery.
Protein: KDPA_YERPY
Sequence: MVASGFLLIASFMLVLFVLSRPLGGFLARLIEGEPFSALQKVEAGLWRCSGVKNAEMNGWQYALAILCFNLLGIVLLFVLLMTQGSLPLNPEHLPGMSWHLALNTAVSFVTNTNWQAYSGENTLSYLSQMAGLTVQNFLSAATGIAVAFALIRAFARHSATTLGNAWVDLVRITLYVLLPIALIIALIFVSQGVLQNLDGYLHITTLEGVQQTLPMGPVASQEAIKVLGTNGGGFFGANSAHPFENPTAFSNFVQMLAIFLIPCALCFAFGQVVGDNRQGHALIWAMSLIFIVAVVVVMYAELAGNPHLSPLGADSNSNMEGKESRFGILATSLYAVVTTAASCGAVNAMHDSFTALGGMIPLWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVFDMKMTALAILVTPTIVLLGTALALCTEAGRAGILNPGAHGFSEVLYALSSAANNNGSAFAGLSVNTPFYNLLLAAAMFIGRFGVILPVLAIASSLVAKKRQPAGNGTLPTGGPLFIGLLIGTVLLVGALTFIPALALGPVAEHLQVWLAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF2M_LODEL
Sequence: MIVRNLLGKNRLCCLQPKLLLSTLSQRPQLQLSLQLLCRATRLYATVNDIALPKTRNIGIIAHIDAGKTTTTERMIYYSGKSKRIGNVDEGDTVTDYLQAERERGITIQLAAITIPWNNHKINIIDTPGHADFTFEVIRSLRVLDGAVTILDAVAGVEAQTEKVWKQASALKLPRMIYVNKMDRPGAGFSRTVKEVIQKLETRVVLCNTPFFENQELNPEFRGVIDVIHGKLLKWKEADEFGKEIDVEDIDETKPELYDVYCKAREYMVETLGEYDESIIDAFLENDENYLKISPELLNRAIRKATIDNYLVPVFCGASFRNIGVQPLMDGITNYLPSPLETPVPDIKSKKKQEISAKMANNGLIINNDPKLTVGLVFKVMNHATRGPMAFVRIYSGKLVANSMVVNSRTGAKHSVRKLLIMHGDQPEEVKFIGAGNIGVISGFEDEFHTGDTVISHATSKKAVGTMESTIKLMPIDIPPPLFNSSIEPFTAGDEAHMKKCIDILIREDPSLKVHTEEDMGQTILSGMGELHLEIVRDRLINDMKVKANLRDIAVAYKESYIGKTPTNGLFETESIQVKLSIEHVDDCKSFEDVDGAIIFEDQNNVIIVPESLASETVQSATEGRRWKCPSSYEELHEAVVNGCSMALQTGGPHLGLSLHSTLVKVEFWNAPVEVNEELIPPLMNAAREAVQSVKASENKFGFLEPLMNVRVFVDSADMGEVSHDLSQRCQALIHSVEDESLLNLETANWAKDEAERAYLPPDYTMSKTALADNYKTRKVIHAETPLKEMIGYLSKLRSLTGGKATFDMSFLGMRRVTQSRLNQIF
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HTPX_ECO81
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SAMN1_MOUSE
Sequence: MLKRKPSNASDKEKHQKPKRSSSFGNFDRFRNNSVSKSDDSIEVHDRELTNGSEEQSKTSSSGGSLGKKVRAISWTMKKKVGKKYIKALSEEKEEESGEEALPYRNSDPMIGTHTEKISLKASDSMDSLYSGQSSSSGITSCSDGTSNRDSFRLDDDSPYSGPFCGRAKVHTDFTPSPYDTDSLKIKKGDIIDIICKTPMGMWTGMLNNKVGNFKFIYVDVILEEEAAPKKIKVPRSRRRENHQTIQEFLERIHLQEYTSTLLLNGYETLDDLKDIKESHLIELNIADPEDRARLLSAAESLLDEETTVEHEKESVPLSSNPDILSASQLEDCPRDSGCYISSENSDNGKEDLESENLSDMVQKIAITESSD
What is the function of this protein?
Negative regulator of B-cell activation.  Down-regulates cell proliferation (in vitro).  Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton.  Regulates cell spreading and cell polarization.  Stimulates HDAC1 activity.  Regulates LYN activity by modulating its tyrosine phosphorylation.
What are the official names of this protein?
SAM domain-containing protein SAMSN-1, SAM domain, SH3 domain and nuclear localization signals protein 1, SH3 protein expressed in lymphocytes 2, SH3-lymphocyte protein 2, SLy2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, ruffle. Note=Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
Protein: SUCC_MYCTA
Sequence: MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDIKGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGHLPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGITSCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ATG1_BEAB2
Sequence: MTSRQEGASSHGSRRSSRHVGSFIIDREIGKGSFAQVYMGWHKESKAAVAIKSVELERLNKKLKENLYGEIQILKTLRHPHIVALHDCVESSTHINLIMEYCELGDLSLFIKKRDKLITHPATHDMARKYPSAPNSGLHEVVIRHFLKQLSSALEFLRAKNYVHRDVKPQNLLLLPSQAFREERALPIMEASQDSLIPISGLASLPMLKLADFGFARVLPSTSLADTLCGSPLYMAPEILRYERYDAKADLWSVGTVLYEMITGRPPFRARNHVELLRKIEAAEDVIKFPREVSVTPDLKALVRSLLKRSPVERLSFENFFAHHVVTGDILGLVEDDIPKPPKRELETIRQGEALPSSPRVQMARQLSSDPRDTRSSPKSPRSSPRSSTVNSSADAAPRRQSQNAERRLSISSHNSGQGLGIQRPAPPIQSHTAPNHPRAADRSGREPQPSSLRVARQPSDVSLTEEEKAAQDVMFERDYVVVERRHVEVNALADELAANEKLGQNNSSAKSSPLQRRYTQQGSATSTTGAIPTPASRTALVAQGRAGQDRRSSYEKALSASPGSASSAISKAIQDASLRLFGYKVNTMRQKGSSPPLYQPFPAYPTPTSAGLLSDGKGSQVSDEDAKAAQAIEEFATRSDCVYGFAEVKYKQLLPMAPSMDYGLGGVSPDKGTSEEDGLTVDATVALSEEALVLYVKSLTLLARAMDIASLWWSKKTRAESSVVSQTLVQRINAVVQWVRQRFNEVLEKSEVVRLKLTEAQKLLPEDHPSNPAHQGEDSIASSAVGAKQVYLTPGISAEKLMYDRALEMSRAAAIDEVTNENLPGCEISYLTAIRMLEAVLDSDDEATARNISSGKEIAKDATQEGSDLDTEEAAHVRKMITMITGRLNMVRKKQQMIAEANNQAKHVSAMRRLSGDVTPRSVPSYGST
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes (PubMed:27197558).  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates (By similarity).  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8 (By similarity).  Contributes to conidiation by regulating the conidial levels of the conidiation-related protein CP15 and mediates fungal oxidation resistance by controlling total superoxide dismutase (SOD) activity (PubMed:27197558).
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: U17_HHV6U
Sequence: MADERTSDSVKTRYDIALMKLNDIKIAVFRDSLSTYVEQKTGLTIQFNWPKSRCLVISTLCKIPFPTKSAAELQEMCKYQCFVSVLWCVILVFVVKIKLFFLLNKVRYYFAARKDCNYLDMFLSGERRLVMCA
What are the official names of this protein?
Protein U17.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CNMD_MOUSE
Sequence: MTENSDKVPITMVGPEDVEFCSPPAYTTVTVKPSGSPTRLLKVGAVVLISGAVLLLFGAIGAFYFWKGNDNHIYNVHYSMSINGKLQDGSMEIDAVNNLETFKMGSGAEEAIEVNDFKNGITGIRFAGGEKCYIKAQVKARIPEVGTVTKQSISELEGKIMPANYEENSLIWVAVDQPVKDSSFLSSKILELCGDLPIFWLKPMYPKEIQRERREVVRNSAPSTTRRPHSEPRGNAGPGRLSNGTRPNVQDDAEPFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVVMPCSWWVARILGMV
What is the function of this protein?
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells.  May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development (By similarity).  Inhibits in vitro tube formation and mobilization of endothelial cells (By similarity).  Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
What are the official names of this protein?
Leukocyte cell-derived chemotaxin 1, Chondromodulin.
What is the protein family that this protein belongs to?
Belongs to the chondromodulin-1 family.
What are the subcellular locations of this protein?
[Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Note=Accumulated in the inter-territorial matrix of cartilage. SUBCELLULAR LOCATION: [Chondrosurfactant protein]: Endomembrane system; Single-pass membrane protein.
Protein: CITT_BACSU
Sequence: MIHIAIAEDDFRVAQIHERLIKQLDGFKIIGKAANAKETLALLKEHKADLLLLDIYMPDELGTALIPDIRSRFPEVDIMIITAATETRHLQEALRAGIAHYLIKPVTADKFRQVLLQYKEKRKLLMSQPEVSQSMIDHIFGNGVKTALPAEDLPTGINSITLRKIKEALQTASEGLTAEELGEKMGASRTTARRYAEYLVSKEEARAELEYGIIGRPERKYYLAAD
What is the function of this protein?
Member of the two-component regulatory system CitT/CitS.  Regulates the expression of the citM-yflN operon.  Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon.
What are the official names of this protein?
Transcriptional regulatory protein CitT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_YERPB
Sequence: MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRT_ORYLA
Sequence: MRRQASLPARRRRRVRRTRVVRRRRRVGRRRH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: COXX_PROMM
Sequence: MVSSTPEMLQGGVTREQIVPSRKRIKLPAWLEIAKPRLIPLLLATTLGGMALSEGWPLPSLRLACTLGGGALAAAAAGVLNCIWEQDLDGRMQRTSGRALPSGRLSPTAAFIGAISCTLAAAALLVSGVNCLAAGLSLLGLCSYVLLYTAILKPRTPQNIVIGGVAGAIPPLVGAAAASGHVGLSGWWLFSLVMLWTPAHFWALALLLRDDYRAVGIPMLPVIQGPVVTVRAISRYGWATVLLSGFGVWALPEGGLLYGLLLIPFNARLLQMVHQLGAAPENVDRAKGLFRWSIFYMFGICLLLVVSRLPMAANFDLQAWSLLQQMASSGQFI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PER2_MAIZE
Sequence: MAAATAPKTMPSSVFAAALLLLAAAACQASPYYPLELGYYRYTCPQAEAIVKASMEKAIAQNPGNGAAVIRMLFHDCFVEGCDASVLLDPTPFSPTPEKLAAPNNPSLRGFELIDAIKDALEAACPGVVSCADIIAFAARDASCFLSQGKVSFDMPSGRLDGTFSNASESVKFLVPPTSNLSDLASSFAVKGMSLEDLVVLSGAHTVGRSHCSSFVSDRLDVPSDINPALAAFLRTRCPPNTTTSDDPTVMQDVVTPNAMDIQYYKNVLSHTVLFTSDAALLTSPETAKLVLDNAKIPGWWEDKFEKAMVKMASLEVKTGHQGQVRKNCRAINHY
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 2, Plasma membrane-bound peroxidase 2, pmPOX2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXC_LEGPL
Sequence: MIKQRTPKKVIQATGVGLHSGEKVLLTLRPAPVNTGIVFRRVDLSPVVEIPASYEYVGDTMLCTTLHHGKVKIATVEHLLSALAGLGIDNAYIDVNAPEIPIMDGSAAPFVFLIQSAGIREQNAAKRYIRILKPIRVEENGKYVQFLPHKGYKITFTIGFEHPVFNDRPQTVSFDFSGTSYVKEVCRARTFGFLSDYEKLRECDLAKGGSLDNAIVVDDYRVLNEDGLRFESEFVTHKVLDAIGDLYLLGSSLIGAFEGYKSGHELNNRLLRELMIRQDAWEYTYFDTENYLPAVHPEYYPVEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: C42ES_DROME
Sequence: MASTGEIWLQWFSCCFQQQRSPSRRPHQRLRIDRSMIGNPTNFVHTGHIGSADVELSANRLNAISTQMQSKGGYETNSIHSLHAC
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.
What are the official names of this protein?
CDC42 small effector protein homolog, Dspec.
What is the protein family that this protein belongs to?
Belongs to the CDC42SE/SPEC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor.
Protein: MIAA_WOLPP
Sequence: MKDNIVIITGITASGKSELCDNLIKKHKNISIINCDSKQVYKEIPVITAQPPKQKEFYRLYGYVSARENYSVGLWLEDLKREVNNALKNSRIPIITGGSGLYISSLIKGLSSIPQISQEVRENVNELRKNLSKEEFYKLVLSKDPRIQGKIFINDSHRLSRALEVITETGKTIFVWQENRQPPLFNNFKVYTILPKREDIYRKINSRFIEMVENGAIDEVKNLLSMNPSPHLPAMKAHGVPEIIRYLKGEITLDEAIQIAQTNTRHYAKRQYTWFKNQFPNSQVIDCANKLTEFGIF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AGR3_HUMAN
Sequence: MMLHSALGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIMFVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL
What is the function of this protein?
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway.  Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
What are the official names of this protein?
Anterior gradient protein 3, AG-3, AG3, hAG-3, Anterior gradient 3 homolog, Breast cancer membrane protein 11, Protein disulfide isomerase family A, member 18.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Found in the cytoplasm, which could include the endoplasmic reticulum.
Protein: YBIX_ECO57
Sequence: MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFIWIQSMIRDDKKRAMLFELDKNIQNIQSLKSRYGENEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.