PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_PEDPA
Sequence: MNLVPTVIEQSSRGERAYDIYSRLLKDRIIMLSGPIDDDLANSIISQLLFLDAQDSEKDIYLYINSPGGVVTAGLAIYDTMNFIKSDVQTIVMGMAASMASVLASSGTKGKRFALPHSEVMIHQPSGGAQGQQTEIEIAAEQILKTRKELNTILAENSGQPLEKINIDTERDNYLSAQDAVEYGLIDGIMEKNANLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PRIM1
Sequence: MASLRDIQTRITSTKKTSQITKAMEMVSAAKLNRAEQNAKSFVPYMEKIQEVVSSVALGSRGASHPMLTARSVKKTGYIVITSDRGLAGAYNSNILRKVSQAIEERHQSPDEYGVIAIGRVGRDFFVKRGIPVLLEITGLADQPAFADIQGIASQTVQMFADGTFDELYLYYNHFINTISQEVTEKKLLPLTDLQPSGKLVGYEFEPSQEEILEVLLPQYAESLIYGGLLDGKASEHAARMTAMKSATDNAKDLINNLTLSYNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBB_CALJA
Sequence: MVHLTGEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMNNPKVKAHGKKVLGAFSDGLTHLDNLKGTFAHLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPVVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SFSA_BRUA2
Sequence: MLFPTPLISGRLERRYKRFLADVTLDDGRFITASVPNTGSMLGLTAPGSRVWLSFSDAPHRKYAHTLQIVEADNTLVGVNTGLPNRIAEEAILKGLIPDLDGYATLKREQKYGRNSRIDLLLDDGPRPRAYVEVKNVHFIRTPGLAEFPDTVTARGAKHLDELVDVVAAGHRGIMLFIIQRADCSRFGISGDLDPFYARAFERAIASGVEAWAVRCHITENGIDATELVPIEDMRRIE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: COAA_ECO7I
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_XYLF2
Sequence: MGVIQAIDRLMTNPIPDGQVDDILRPQGESPLLQKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGAARLDLDRYGIVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGILQLQKKIWRTKTIAG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPON1_XENLA
Sequence: MGLIFQPLFWQYVATSYALMVLGFLDETVEKAIKSEGYCSRILRAQGGTRKEGYNEFSMRVEGDPEFYKPGNTYRVTILAVSPAYFRGFTLIALKEGKEGEKEEDHAGSFQIIDEEDTQFMSNCPVAVTESTPRRRTRIQVFWTAPSIGTGCVILKASIVQKKIIYFQDEGSLTKRMCELDLTLEGGNEKTIPDCCACGTAKYRLTFYGNWSEKAHPKDYPRRANHWSAIIGGSHSGEYVLWEYGQASDGVKQVAELGSPVKMEEEIRQKGDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRSRHLMSFLAMMGPSPDWNVGLTSEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQDKIRPLTSLDHPQSPSMTRGGPIIPIARVVIERIARKGEQCNIIPDNVDDIVADLVTEEKDEDDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSVPCPDTQDFEPCMGPGCSDDEASTCMMSEWITWSPCSASCGMGIEVRERYVKQFPEDGSLCKVPTEETEKCIVNEECEPSSCIVTEWAEWEECSATCRMGMKKRHRMIKMTPADGSMCKADTTEVEKCMMPECHTIPCVLSPWSEWSDCSVTCGKGTRTRQRMLKSPSELGDCNEELELKQVEKCMLPECPISCELTEWSYWSECNKSCGKGHMIRTRMITMEPQFGGAVCPETVQRKKCRLRKCQKSSGNERRHLKDAREKRRSEKIKEDSDGEQYPVCKMKPWTAWTECTKFCGGGIQERFMTVKKRFKSSQFTSCKDKKEIRACNVHPC
What is the function of this protein?
Promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro.  May contribute to the growth and guidance of axons in both the spinal cord and the PNS.
What are the official names of this protein?
Spondin-1, F-spondin.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL14_BURO1
Sequence: MIQTESRLEVADNTGAREVLCIKVLGGSKRRYAGIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FIS1_YARLI
Sequence: MKKEDYLPNLVDIESPLSDEELYVLSQQYNNEGDFVSVQTRFNYAWGLIKSRKVEDQQLGVQILAQVYKDTPSRRRECLYYLAIGSYKLGEYTDARKYCDLLLQIEPDDPQSAKLRQIIEDKLAKEGMIGIAIVGGVIAVGAAVLGAVLSQKKR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: PFP_GIAIC
Sequence: MSAFEVYRRKFKPALPRAIQGASYHLHTEEKTHPVADEQDIAALFPKTTHLPLLDIQPDTGAPKLLEPKRVGVIFSGGQAPGGHNVLCGLYDKLQQIAPKSVLLGFQNGPKGLMTNKYVELTEKFLEPFRNMGGFHAIGSGRDKIAKPEDFDAAAKTAKDNNLDIICIIGGDDSNTNACLLAEDFLKRGLKTAVIGVPKTIDRDLYSTKGIECSFGFDSSTKVYAELIGNICYDCLSAKKYWHFIRLMGRSASHITLECGLQTHANICLVGEEILSKKMTSRQLFEYLADCVTKRADSGKNYGVCLVPEGLIEFIPENNELFAYLNNTLLPHWTGELTADAVAAKLPDPLRTTFMAIPASIRTQLLLDRDPHGNIAISQIETEKFLGAGVQQVLRERGSKTKFTPLYHFFGYEGRCAAPSDFDCSLCYSLGAVAAILGCNGKTGYMASLRNLVRPPADWSPIGLPLTCLMNMEMRHGHKTPVIMKQMTDLNGNPYKLLARNRDTWLMNDDYQNPGPIQQIATESAEGTAVCARPTITLIEEARK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, 6-phosphofructokinase, pyrophosphate dependent, PPi-dependent phosphofructokinase, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_NITOC
Sequence: MMNTRVWCKIIGMLALLVWLVSSPSVFAVLTIEITGGTEAALPIAIVPFQNEGSTPPENVAAVIAADLARSGRFAPLPEEDLISRPRNASDIQFQDWRRLGSEGLVIGKVISLGADRYEVRFQLFDIYKEEQLVGRRYQVPAAGLRHLAHQIADLIYETLTGEKGIFTTHIAFVTVSRAAHGAKQYSLQVADVDGHNPHTILRSKEPILSPAWSPDGTQLAYVSFERRRSEVFVQELRTGQRQSVASFSGINSAPDWSPDGGKLALVLSKEGNPEIYIRDLATGRLTRLTHNTAIDTEPAWAPDGGSIVFTSDRGGRPQLYQIPVSGGRAQRLTFDGAYNASASFAPDGRRLALIHGDKGQFHIAVLNLQSKELQVLTETRMDESPSFAPNGRMILYATSSPQGGVLAAVSTDGRVRQRLAQQGDEVREPAWSP
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYP_ACAM1
Sequence: MRLSQMLFVTLREDPAEAEIPSHKLLLRAGYIRRVGSGIYAYLPLMWRVLQKVSQIVREEMDAAGAQECLLPQIQPAELWQESGRWDTYTQAEGIMFALQDRQDRELGLGPTHEEVITAVARDMIRSYRQLPLNLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFSTDEADLKIIYSKMHDAYCNILQRSGLAYRAVDADSGAIGGSGSQEFMVLAEAGEDEVLYTDDGKYAANVEKAVSRPADAQPSSFKSVEKKETPKTDTIAKLCDCLQCSPTQVVKTVLYEAVYDNGQTLLALVSLRGDQSVNEVKLQNELVQLGDVVKGKALIALTVAEGGTKWASQPLPLGYIAPDLADSYIQKSKQVHGKFVRLVDQTAVDLKNFVTGANEVGIHQVGVNWKTDIPLPKHVVDIRTAQVGDRAVHDPKQTLQTARGIEIGHIFQLGTKYSQALGATYTNEAGKEQPLVMGCYGVGVSRLAQAAVEQSYDKDGIVWPVAIAPYHAIIIIPNGKDSDQVEAAEKLYSELNAAGIETLLDDRTERAGVKFKDADLIGIPYRIVTGRSLKEGNVEMVERATHDAHQIALDQVLPTLKEYLAKAIST
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIT1_SPIOL
Sequence: MASMALSLTSSPTYSLSFRSLPSLKPLSKSQPSISLPSLRSNASKSPSLSHKHFLSPPSLLLPHKLKPISASSPTNPPPPPAPVPSPAPVSAPAQVQPWQGASIKPLLASILTGVIIWFIPTPEGVSRNAWQLLAIFLSTIVGIITQPLPLGAVALMGLGASVLTKTLTFSAAFSAFGDPIPWLIALAFFFARGFIKTGLGNRIAYQFVKLFGSSSLGLGYSLVFSEALLAPAIPSVSARAGGIFLPLVKSLCIACGSNVGDGTERKLGAWLMLTCFQTSVISSSMFLTAMAANPLSATLTFNTIGKAIGWMDWAKAAFVPGLVSLIVVPLLLYVVYPPEIKSSPDAPRLAKEKLDKMGPMTKNESIMAVTLLLTVGLWVFGGKLGVDAVTAAILGLSVLLITGVVTWKECLAESVAWDTLTWFAALIAMAGYLNKYGLITWFSENVVKVVGGLGLSWQMSFGVLVLLYFYSHYFFASGAAHIGAMFTAFLSVASALGTPPFLAAIVLSFLSNLMGGLTHYGIGSAPVFYGANYVPLPQWWGYGFLISIVNLIIWLGVGGLWWKAIGLW
What is the function of this protein?
2-oxoglutarate/malate translocator that transports carbon skeletons into chloroplasts for net glutamate synthesis.  This translocator exchanges malate for internal succinate, fumarate and 2-oxoglutarate but not for aspartate and glutamate.  Involved with DIT2 in primary ammonia assimilation and in the re-assimilation of ammonia generated by the photorespiratory pathway.  Imports 2-oxoglutarate into plastids as precursor for ammonia assimilation.  2-oxoglutarate is converted to glutamate, the end product of ammonia assimilation, which is exported to the cytosol by DIT2.
What are the official names of this protein?
Dicarboxylate transporter 1, chloroplastic, SODIT1, 2-oxoglutarate/malate translocator.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: MIAB_RHORT
Sequence: MANRKLFIKSYGCQMNVYDAGRMADVMAPLGYDLVSEADGADLVILNTCHIREKAAEKVFSDLGRLRPFKEAMAAEGRRMLVAVAGCVAQAEGAELMARAKIVDMVVGPQAYHRLPEMVAKVERGAGRVLDTDFPIEPKFDFLPAPQAHGPSAFLSVQEGCDKFCTFCVVPYTRGAEYSRPVADVLREAALLAEGGVREITLLGQNVNAYHGEAPDGRTWGLGRLARALAEIPGVARLRYTTSHPRDVDDDLIAAHREVAALTPFIHLPVQSGSDRILAAMNRGHDVEGYRRIIDRLRAARDDMAFSSDFIVGFPGESERDFQATLALIDEVRFIQAYSFKYSPRPGTPAAALSAQLPEAEKSARLIALQARLVEIQQAFNQACVGRPMDVLLDRPGRHAGQLVGRSPWMQPVHLEAPAALLGTLAPVVVETATSNSLAARLVEGNSSMSSDRVLAEEAPPPARIRA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTK7_DROER
Sequence: MTARMISIYGLVLASMMASVWASSSRFQRLPQSQSVVENESVKFECESTDSYSELHYDWLHNGHRIAYDKRVHQIGSNLHIEAARRTEDVGSYVCIATNLASGAREASPPAKLSVIYLESASVQLLGSNRNELLLKCHVEGASGDSEPLEIEWYRNSEKLSTWKNVQLDQHRLIIRQPGSDDDGLYRCTASNAAGRVMSKQGYAYQSSVKCLPRLARRKNQKMMESWDKQTFLCRGKRGGAAGLEALPAAPEDLRIVQGPVGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQVELGGSAPITGHSFDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEGHLPISSTPGVLEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENSTLPDQVEVDANGTLIFRNVNSEHRGNYTCLASNTQGQINATVAINVVVTPKFSVPPVGPIETSEQGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGNSAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPDAAGNGKGSEQEPCLSKQHNGHSKSRSKSSGDAQKSDDTACSQQSRASKKSAHIYEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPTDKDADTEKQHSNSENGSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQEQHNQSALEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRARFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHEELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCWVSNPKERPSFSQLGAALSKAMQSVEK
What is the function of this protein?
Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system.  Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage.  Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase-like otk, Tyrosine-protein kinase-like 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FTIP1_ARATH
Sequence: MAAKDGAKSQEDYKLKDMKPELGERWPHGGQRGGTGWIGSERAASTYDLVEQMFYLYVRVVKAKDLPPNPVTSNCDPYVEVKIGNYKGKTKHFEKRTNPEWNQVFAFSKDKVQSSTVEVFVRDKEMVTRDEYIGKVVFDMREVPTRVPPDSPLAPQWYRLEDRRGESKKRGEVMVAVWLGTQADEAFPDAWHSDASSVQGEGVQSVRSKVYVSPKLWYLRVNVIEAQDVEPSDRSQPPQAFVKVQVGNQILKTKLCPNKTTNPMWNEDLVFVAAEPFEEQFFLTVENKVTPAKDEVMGRLISPLSVFEKRLDHRAVHSKWYNLEKFGFGALEGDKRHELKFSSRIHLRVCLEGGYHVMDESTLYISDVKPTARQLWKSPIGILEVGILSAQGLSPMKTKDGKATTDPYCVAKYGQKWVRTRTIIDSSSPKWNEQYTWEVYDPCTVITLGVFDNCHLGGSEKSNSGAKVDSRIGKVRIRLSTLEADRIYTHSYPLLVLQTKGLKKMGEVQLAVRFTCLSLAHMIYLYGHPLLPKMHYLHPFTVNQLDSLRYQAMSIVAARLSRAEPPLRKENVEYMLDVDSHMWSMRRSKANFFRIVSVFAGLIAMSKWLGDVCYWKNPLTTILFHVLFFILICYPELILPTTFLYMFLIGLWNFRFRPRHPAHMDTKVSWAEAASPDELDEEFDTFPTSKGQDVVKMRYDRLRSVAGRIQMVVGDIATQGERFQALLSWRDPRATCLFVIFCLVAAMILYVTPFKIIALAGGMFWMRHPKFRSKMPSAPSNFFRKLPSKADCML
What is the function of this protein?
Involved in the export of FT from the phloem companion cells to the sieve elements through the plasmodesmata (PubMed:22529749).  Regulates flowering time under long days (PubMed:22529749, PubMed:29259105).  May function as a signaling molecule by regulating the trafficking of other regulators (PubMed:29259105).
What are the official names of this protein?
FT-interacting protein 1, Multiple C2 domain and transmembrane region protein 1.
What is the protein family that this protein belongs to?
Belongs to the MCTP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, plasmodesma. Note=Localized in plasmodesmata between companion cells and sieve elements.
Protein: LYS3O_CATAD
Sequence: MKNLSAYEVYESPKTSGESRTEAVSEAAFESDPEVSAILVLTSSEASTLERVADLVTAHALYAAHDFCAQAQLAAAELPSRVVARLQEFAWGDMNEGHLLIKGLPQVRSLPPTPTSNVHAVAATTPMSRYQALINECVGRMIAYEAEGHGHTFQDMVPSAMSAHSQTSLGSAVELELHTEQAFSPLRPDFVSLACLRGDPRALTYLFSARQLVATLTTQEIAMLREPMWTTTVDESFLAEGRTFLLGFERGPIPILSGADDDPFIVFDQDLMRGISAPAQELQQTVIRAYYAERVSHCLAPGEMLLIDNRRAVHGRSIFAPRFDGADRFLSRSFIVADGSRSRHARSSFGRVVSARFS
What is the function of this protein?
Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (3S)-3-hydroxy-L-lysine.  Can also use (5R)-5-hydroxy-L-lysine as substrate, but neither D-lysine nor L-ornithine.
What are the official names of this protein?
L-lysine 3-hydroxylase, Alpha-ketoglutarate-dependent dioxygenase, KDO1, L-lysine hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the clavaminate synthase family.
Protein: RS20_AERSO
Sequence: KRALQSEKRRQHNASRRSMTRTYLKKVIAAIASGDKAAATAAFAVAQPIMDRMATKGLIHKNKAARHKSRLS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ERH_CAEEL
Sequence: MSHTILLLQPTDNIESRSWSDYENTTECLEGICRVYEEYLKKKVPAQNEITYDISHLFEFIDDLKDLSMLVLDNTTYTYVPHNKQYVKESIYKLMNNRLNNQH
What is the function of this protein?
May have a role in the cell cycle.
What are the official names of this protein?
Enhancer of rudimentary homolog.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
Protein: Y4333_HERA2
Sequence: MANTTITWLGHASFLFVTPEGKRIVLDPWYEGNPSFPESAKAELEHVDAILLTHGHMDHTGNAITLAQQTKAPVAGIVELIGWVQGQGVDATQCIGFNKGGCIELAGIKATLTTAHHSSSISSGSISLYLGDPCGFILEFSDGCVVYHTGDTCVHGDMALMGEIYQPNVTILPIGDFYTMGPRQAAHALKLIGSKFAIPEHYGTFPALHGNPEALQSELNKLQLNTAIVALQPGEAWTYPA
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Haur_4333.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: OMA1_DANRE
Sequence: MQQTCIRLVKLDMLSTLTRFRTHSAIRCCAQRLFHCRPSLFISARTYFIKIDSSSLPKLKGSVSFSASCVSLGSSRLGLCSSSFKTGAPAALRAPVVFQRTRGFHTSGRRRALPALPLLWMVLKPLQKIMAIILGRSIRKWWVALPANKKQLFREWSWRRRWHFLGAGTGLLFIASLFFFTHLDESPITGRTRLLVFSRKNFRELAQFNADAFMEEFKDSLIASSDPRHKVVEQVVQILAQRNQDIAEISAVPWTVHVVDSPTMNAFVLPNGEIFVFTGMLNAVTDIHQLTFILGHEMAHALIGHAAEQASLSHVVELLSLVLLTAIWAVCPRDSLAALGHWIQGKLVQFLFDRPFSRKLEAEADQVGLQMAAKACADVRAGPVFWEQMEIFDQLSGQPTMPEWLSTHPSHQNRVRQLDRLIPEALELRARCNCPELPKTDPRVVFNEAVRLVLEGKKEQMLEKEEKNGKTQTGDMFP
What is the function of this protein?
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria.  Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as opa1 and dele1.  Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of opa1 at S1 position, leading to opa1 inactivation and negative regulation of mitochondrial fusion (By similarity).  Also acts as an activator of the integrated stress response (ISR): in response to mitochondrial stress, mediates cleavage of dele1 to generate the processed form of dele1 (S-DELE1), which translocates to the cytosol and activates eif2ak1/hri to trigger the ISR (By similarity).  Required for the stability of the respiratory supercomplexes (PubMed:26365306).
What are the official names of this protein?
Metalloendopeptidase OMA1, mitochondrial, zfoma1, Overlapping with the m-AAA protease 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PTSO_KLEOX
Sequence: MTVKQTVEISNKLGMHARPAMKLFELMQNYDAEVLLRNDEGTVAEANSVIALLMLDSAKGRQIEIEANGPQEVEALAAVIALFNAGFDED
What is the function of this protein?
Component of the phosphoenolpyruvate-dependent nitrogen-metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein NPr by enzyme I-Ntr.  Phospho-NPr then transfers it to EIIA-Ntr.  Could function in the transcriptional regulation of sigma-54 dependent operons in conjunction with the NPr (PtsO) and EIIA-Ntr (PtsN) proteins.
What are the official names of this protein?
Phosphocarrier protein NPr, Nitrogen-related HPr.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDBJ_ECOLI
Sequence: MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEANCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY
What are the official names of this protein?
Uncharacterized protein YdbJ.
Protein: RR16_TRICV
Sequence: MLKLRLKRSGRKKQPSYRLVVMENTTRRDGRPVEQVGYYNTITKESYFDVIKIKKWLNYGAKPTQTVLNLLKKAKIIDQ
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATM1_GIBZE
Sequence: MIPQLLQRSSRACPRYNPALYRLSTTSQQRPGLTQTFWTSAPRREQPRTPTDSKPTTTKPSAVFPANKKATKQNDPLVTVEKSAPEQRKADWAIMKEMTRYLWPKDDWGTKLRVSLAVSLLIGAKVLNVQVPFYFKSIVDSMNIDVAAVGGTATTVAGAMILAYGASRIGATVFQELRNAVFASVAQNAIRKVACNVFDHLLRLDLTFHLSKQTGGLTRALDRGTKGISFILSSMVFHVLPTALEISMVCGILTYNYGAKFAALTVLTMVSYTAFTIWTTAWRTKFRRQANAADNKASTVAVDSLINYEAVKYFNNEKFEVARYDKALGQYEKNSIKVATSLALLNSGQNIIFSSALTGMMYLAANGVAEGTLTVGDLVMVNQLVFQLSVPLNFLGSVYRELRQSLLDMETLFNLQKVNANIKEKAGAKPLVLSKGGEIKFENVNFAYHPNRPILRDLSLTIPAGKKVAVVGPSGCGKSTLLRLLFRSYDVQGGRVLIDDQDIRDVDLESLRRSIGVVPQDTPLFNDTVEHNIRYGSINATHEEVVAVAKRAHVHNTIQSFPDGYETKVGERGLMISGGEKQRLAVSRILLKDPPLLFFDEATSALDTHTEQALMMNINSILRERGRTSVFVAHRLRTIFDSDLIIVLKEGHVAEMGTHRELIDRDGVYAELWSAQETMFGEDGKEKSEEENDEQKKN
What is the function of this protein?
Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (By similarity).  Hydrolyzes ATP (By similarity).  Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).
What are the official names of this protein?
Iron-sulfur clusters transporter ATM1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL9_AFIC5
Sequence: MEVILLERVAKLGQMGDIVTVKNGYARNFLLKRHKALRATADNRAKYEGMKADLEAKNIAAKGEAAKVAEKIEGRNVVIIRQASEGGQLYGSVSVRDIMAALAADGVSLSRHQVLLEHPIKEIGQHKITIAVHPEVEIHVTATVARSEAEAERINRGEDINSRQEDQDAAAEAIAAAGEFFDPEAQDETPETEAASEQQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.