PharMolix/UniProtQA huggingface dataset:
Protein: RAI3_HUMAN
Sequence: MATTVPDGCRNGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKMLPTQFLFLLGVLGIFGLTFAFIIGLDGSTGPTRFFLFGILFSICFSCLLAHAVSLTKLVRGRKPLSLLVILGLAVGFSLVQDVIAIEYIVLTMNRTNVNVFSELSAPRRNEDFVLLLTYVLFLMALTFLMSSFTFCGSFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLPDFDRRWDDTILSSALAANGWVFLLAYVSPEFWLLTKQRNPMDYPVEDAFCKPQLVKKSYGVENRAYSQEEITQGFEETGDTLYAPYSTHFQLQNQPPQKEFSIPRAHAWPSPYKDYEVKKEGS
What is the function of this protein?
Orphan receptor.  Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.  This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.  Functions as a negative modulator of EGFR signaling (By similarity).  May act as a lung tumor suppressor (PubMed:18000218).
What are the official names of this protein?
Retinoic acid-induced protein 3, G-protein coupled receptor family C group 5 member A, Phorbol ester induced gene 1, PEIG-1, Retinoic acid-induced gene 1 protein, RAIG-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in perinuclear vesicles, probably Golgi- associated vesicles.
Protein: XPF_ARATH
Sequence: MALKYHQQIISDLLEDSNGGLLILSSGLSLAKLIASLLILHSPSQGTLLLLLSPAAQSLKSRIIHYISSLDSPTPTEITADLPANQRYSLYTSGSPFFITPRILIVDLLTQRIPVSSLAGIFILNAHSISETSTEAFIIRIVKSLNSSAYIRAFSDRPQAMVSGFAKTERTMRALFLRKIHLWPRFQLDVSQELEREPPEVVDIRVSMSNYMVGIQKAIIEVMDACLKEMKKTNKVDVDDLTVESGLFKSFDEIVRRQLDPIWHTLGKRTKQLVSDLKTLRKLLDYLVRYDAVSFLKFLDTLRVSESYRSVWLFAESSYKIFDFAKKRVYRLVKASDVKSKEHVKNKSGKKRNSKGETDSVEAVGGETATNVATGVVVEEVLEEAPKWKVLREILEETQEERLKQAFSEEDNSDNNGIVLVACKDERSCMQLEDCITNNPQKVMREEWEMYLLSKIELRSMQTPQKKKQKTPKGFGILDGVVPVTTIQNSEGSSVGRQEHEALMAAASSIRKLGKTTDMASGNNNPEPHVDKASCTKGKAKKDPTSLRRSLRSCNKKTTNSKPEILPGPENEEKANEASTSAPQEANAVRPSGAKKLPPVHFYALESDQPILDILKPSVIIVYHPDMGFVRELEVYKAENPLRKLKVYFIFYDESTEVQKFEASIRRENEAFESLIRQKSSMIIPVDQDGLCMGSNSSTEFPASSTQNSLTRKAGGRKELEKETQVIVDMREFMSSLPNVLHQKGMKIIPVTLEVGDYILSPSICVERKSIQDLFQSFTSGRLFHQVEMMSRYYRIPVLLIEFSQDKSFSFQSSSDISDDVTPYNIISKLSLLVLHFPRLRLLWSRSLHATAEIFTTLKSNQDEPDETRAIRVGVPSEEGIIENDIRAENYNTSAVEFLRRLPGVSDANYRSIMEKCKSLAELASLPVETLAELMGGHKVAKSLREFLDAKYPTLL
What is the function of this protein?
Seems to be involved in nucleotide excision repair (NER) of damaged DNA (dark repair mechanism).  Involved in repair of UV light, and probably oxidative damage.  The UVH1/RAD1-ERCC1/RAD10 complex may act as an endonuclease making DNA incision 5' to the lesion site.  In vitro, is implicated in double strand breaks (DSBs) repair and is required for homologous recombination in the presence of non-homologous overhangs.  May mediate the induction of a DNA-damage sensitive cell-cycle checkpoint during the G2 phase.
What are the official names of this protein?
DNA repair endonuclease UVH1, DNA excision repair protein XP-F homolog, Ultraviolet hypersensitive 1, AtRAD1.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_THESQ
Sequence: MEISMDLIKKLREMTGAGILDCKKALEEANGDMEKAVEILRKKGAATAEKKAGRTTKEGIIVAYVHFNGRIGVLLEMNCETDFVARTDEFKELAYNLAKQVAAMKPLYVRREDVPAEVIEKEKEIYRAQIKDKPENIVEKIVEGKLEKFFEQACLYEQTYIFDDTKKVKDLINELIAKTGENIRVSRFTRYEIGEGYED
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC25_DROLT
Sequence: MAKAVDESTYEQRVRALYDKQIRMEAREAGVIKKISKFNSNLLDLKEAVVRHHQKVGKVRKVKMLRCGELEKRANFMEELTQELEATKQRNLVMRDQIKQLNVLARQHRNEVMESIHTLSKTTGTYLNHEALPARVKGVTVLRNDNSDQLIPFDLKATDVEGLESLCQHLQGFNIDAFQWRQLVSLATEMSMDSHTTPTTPPKEAAEGKSIIEIDLTSPTSHI
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: UBIA_RALSO
Sequence: MQSSTAHPSRLALYARLVRIDKPIGTLLLLWPTLWAMWMAADGHPPPALVAIFVVGTVLMRSAGCAINDWADRDFDKHVKRTRERPLTAGLIAPWEALAVAAVLALVAFTLILPLNALTKWLSVAAVLIAGTYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPAPAWLMLAANVLWAIAYDTAYAMVDRDDDLLIGIQTSAITFGRFDVAAIMLCYAGFFGIMAWVGHALALGAAYWIGLAAAAALAGYYYTLLRTRDRMQCFFVFRHNNWFGACVFVGAALAYALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PORB_PSEAE
Sequence: MYKNKKTRPAARTVGCLFALGALGLGSAAHAAEAFSPNSKWMLGDWGGKRTELLEKGYDFKLEYVGEAAANLDGGYDDDKTGRYTDQFALGVHMDLEKILGWKATEFQFTVTERNGKNLSNDRIGDPRAGHISSVQEVWGRGQTWRLTQLWLKQQYFDGALDVKFGRFGEGEDFNSFPCDFQNLAFCGSQVGNWAGSIWYNWPVSQWALRVKYNFAPDWYVQVGAYEQNPSNLETGNGFKMSGSGTKGALLPVELIWQPKVGAEQLPGEYRLGYYYSTAKADDVYDDVDGQPQGLTGNDFKSRGSKHGWWVVAQQQVTSHNGDASRGLSLFANLTVHDKATNVVDNYQQLGVVYKGPFDARPKDDIGLGIARIHVNDDVKKRQRLVNQVNGIDDYDNPLYQPLQDTEYNAELYYGVHVTDWLTVRPNLQYIKQPGGVDEVDNALVAGIKIQTVF
What is the function of this protein?
Substrate-selective channel for a variety of different sugars.  Could potentially facilitate the diffusion of diverse compounds, dependent on the presence of a hydroxyl group, but is presumably restricted to carbohydrates.  Involved in the transport of glucose, mannitol, fructose and glycerol (sugars able to support the growth of P. aeruginosa).  Facilitates glucose diffusion across the outer membrane.
What are the official names of this protein?
Porin B, Glucose porin, Outer membrane protein D1.
What is the protein family that this protein belongs to?
Belongs to the OprB family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: EPSH_BACSU
Sequence: METPAVSLLVAVYNTETYIRTCLESLRNQTMDNIEIIIVNDGSADASPDIAEEYAKMDNRFKVIHQENQGLGAVRNKGIEAARGEFIAFIDSDDWIEPDYCEQMLRTAGDETDLVICNYAAEFEDTGKTMDSDIAQTYQDQPKEHYIKALFEGKVRGFSWNKLYRRSMIEAHRLSFPLRGELEHVEDQFFSFRAHFFARSVSYVKTPLYHYRIHLSSIVQRYQKKLFESGLALYETNAAFLQENNKLEEYRKELDTFIVLHSSICMLNEWKTSGSRRLFEKLRNVGVICADPVFQESLSKTGTAPFDAKRSCLLLMAKYRMIPFVAMASAVYQRVIEYKMRNRG
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.  Required for biofilm maintenance.
What are the official names of this protein?
Putative glycosyltransferase EpsH.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: MNTP1_WOLSU
Sequence: MIELLLLSLALSMDAFAVSLGLGARFGYNKRESLRPALSFGIFQGIMPLLGFFVGVTFIAFISAFDHYLAFGILALIGAKMIYEGLSQSEEERLDELSHRTLLILSIATSIDALAAGVSLHLIDVNVFLSCTIIAFTTFLLSYLGVLWGKRAGEQCKRGAEILGGVILIGIGSKILLEHLFF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP 1.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RGF1C_MACFA
Sequence: MPQTLSASDMVTPGSLSPPTTEPTDGEQAGQPLLDGAPSSASLETLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGPKLLQLLAEWTETFPRDFQEESTIGQLKDVVGRIAPCDETYRKRMHQLLQALHQKLAALRQGPEGLVSADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLASTKPCFSDKTSHLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDPSITHYLSTAPIFSEDGLYLASYESESPENQTEKERWKSLRSSILGKT
What is the function of this protein?
Guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Ras-GEF domain-containing family member 1C.
Protein: PLSX_NITEC
Sequence: MSITVAIDCMGGDHGPHVTVPSAVEYLRHDRDTNIILVGRPEILTKELNALNISPDSRLRLYPASEIVGMDEHPAIALRNKKDSSMRVALNLVKNGEAQACISAGNTGALLATSRFVLKTIPGIDRPALAVVLPTISGHTYVLDLGANVNCTAEHLFQFGVMGATLVSSVENKPNPSIGLLNIGEEDIKGNDVVKQAAGLFRSSGLNFYGNIEGDDIYRGTTNVVVCDGFVGNVALKTSEGLAQMLASYLREEFRRSLFSKLAGLVALPVINAFRRRVDHRQYNGASLLGLRGTVIKSHGSADSFAFRCAIKRAVDEIRGGTLRRIVEHIETLRYNIEQNITQPASVE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PUR2_THEKO
Sequence: MRVLLVGAGGRENAIAEVLARDAELYVVAGHKNPGIARLAKDYALAKETDVPRVLDFALKWGVDMAFIGPEAPLEKGIVNVLEENGVPTVGPTREAAMLETNKAFARWLMEEYKIPGRKLFKVFDDVSEMKSWIDDFGRPVVVKPLGLTGGKGVKVVGYQLKDNEEAKAYAEELIKRDGKVLIEERTDGVEFTFQVFTDGKRVVPMPLAQDYPHAYEGDVGPITGGMGSYSCEDHRLPFITKEDYEKALETLKATVEAMRKNGTPYKGILYGQFMLAKDEPKIIEFNARFGDPEAMNVLPILKRSLVEIGEEIVDGNLKGAEFERKATVVKYIAPKGYPTNPVRGIKLHVDEAKIREEGARVYYASLDENFRMLGSRALAVVGIADSLEEAERIASAGIRHVRGEIFYRKDVGTRESIARRIELVRAMRGE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: MDH_ECO7I
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEKNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: Y9423_DICDI
Sequence: MGYQKVVLVAACNILNENISKNDNVLNQNNNINNINNNNYNSNDDNEKIIGNNNISTNNSNLILFNQNNNNNNNCHEERLECQVPFEYIDVYGNADFSFLKYTKRSEFRKYLKKAYNIESLFDKSFRFNSITSFPTIKYYYSLIEDDENIKKKIKEDSYLLLV
What are the official names of this protein?
Uncharacterized protein DDB_G0276289.
Protein: EX7S_HAEIE
Sequence: MARKPASSQDFETTLAKLENIVAHLENGDLPLEEALKEFEQGVQLAKLGQERLQQAEQRIQILLQKTEDAPLNDYKGNDYEGNA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UD11_MOUSE
Sequence: MTVVCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile (By similarity).  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds (By similarity).  Catalyzes the glucuronidation of endogenous estrogen hormones such as estradiol, estrone and estriol (By similarity).  Involved in the glucuronidation of bilirubin, a degradation product occurring in the normal catabolic pathway that breaks down heme in vertebrates (By similarity).  Also catalyzes the glucuronidation the isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin, which are phytoestrogens with anticancer and cardiovascular properties (By similarity).  Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist losartan, a drug which can inhibit the effect of angiotensin II (By similarity).  Involved in the biotransformation of 7-ethyl-10-hydroxycamptothecin (SN-38), the pharmacologically active metabolite of the anticancer drug irinotecan (By similarity).
What are the official names of this protein?
UDP-glucuronosyltransferase 1A1, UGT1A1, UDP-glucuronosyltransferase 1-1, UDPGT 1-1, UGT1*1, UGT1-01, UGT1.1, UGTBR1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PSUG_THENN
Sequence: MVVENRLEKEKPAVGMETTVFVHGLPRKEAIELFRKAKKISEEMGFQLAVVGVLKGKIILGMNEDELTIMMNEGSEKIGTREIPIALAKGMNAATTVSATIFLCKRFGIDVVVTGGTGGVHPGGVDISQDLTEMASSRIILVSSGIKSILDVDATFEMLETLEIPVVGFMTDEFPLFFSRKSGKKVKRVENVEEILRIYRTMEELKLEKTLMVLNPVPEEHEVPREEIEHLLENIELKVEGKDVTPYLLRKLVEITGGRTLKANLSLLEENVKLAGKIALALGR
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: CMOB_ESCF3
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIASWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLIIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLSDFLDPHDPGKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RSMC_PSEPW
Sequence: MDPRSEVLLRQADLFQGPLLIAGAPADDLLGQLPKANAWTWHAGDQAMLDARFAGRSHYGVDVPPVAFEAAVLFLPKSRELAAYLLNALASRLGGGELYLVGEKRGGIEGAAKHLQALGKPRKLDSARHCQLWQVTVDNAPEAKPLESLAERFALELEDGPLQVVSLPGVFSHGRLDRGTALLLKHLDNLPVGHVLDFGCGAGVLGATVKRRYPQSRVTMLDVDAFAVAASRLTLAANKLEGEVISGDGIDAAPGDLSLILSNPPFHTGVHTNYQASENLLKKSGQHLRKGGEMRLVANSFLRYQPLIEGALGNCRTCAEADGFRIYQATR
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_ACIBT
Sequence: MNILIANDDGVFAPGIQALADALKPLGRVVVVAPESERSGFSSALTLDRPLRPIQIAEDVWAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGPDVRSYDHKDDYAQAAKWVHDFIAKGLPALPPRHIFNINIPDVPQLKGTQITYQGRRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPQRIASQIQSDFFAVANSFVSVTPIQMDATNYAVLEDLQASLG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN_HALS3
Sequence: MGNADLRQLAAIEETPFADLEGSVVAVDAHNWLYKYLTTTVQWTGADVYTTSDGTEVANLVGAVQGLPKFFEHGLTPVFVWDGGVTELKDDEIADRREQRERYEEQLDDAREAGDAAEAARLDARTQRLTPTIHETTRELFDLLDIPQVEAPAEGEAQAAYMTRTDDAVDYAGSDDYDCLLLGSPVTLRQLTSSGHPELMDFDATLAEHDLTWEQLVDVGILCGTDFNPGIDGFGPTTALDAIGEHGDLWDVLAAEGEHVAHGDRIRELFLNPDVTDDYVIDPDVSPAIDAARAFVTDEWEVDADAVARGFERIDAAAAQTGLDRWT
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: FKB18_ARATH
Sequence: MASISSLHRWASNQHSRLPRITSISEADQSRPINQVVAFSVPISRRDASIILLSSIPLTSFFVLTPSSSEARERRSRKVIPLEEYSTGPEGLKFYDIEEGKGPVATEGSTAQVHFDCRYRSITAISTRESKLLAGNRSIAQPYEFKVGSTPGKERKREFVDNPNGLFSAQAAPKPPPAMYFITEGMKVGGKRTVIVPPEAGYGQKGMNEIPPGATFELNIELLRVTPPPEEK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP18, chloroplastic, PPIase FKBP18, FK506-binding protein 18, AtFKBP18, Immunophilin FKBP18, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: RAB14_DICDI
Sequence: MSFPYEYIFKYIIIGDMGVGKSCLLHQFTENKFVPDSPHTIGVEFGTRIVDVNNKKIKLQIWDTAGQERFRAVTRSYYRGAAGALLVYDITRRITYNHLTTWLTDARNLTNPNTVIMLIGNKKDLEGQRDVTYEEASAFAKQNGLIFVESSAKTGENVEEAFLRTAKLIFQSVQEGNVDLIPDGGITKNPPQTITDKPQDASKCSC
What is the function of this protein?
Regulates the fusion of phagosomes and lysosomes.
What are the official names of this protein?
Ras-related protein Rab-14, Rab4-like GTPase.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endosome. Contractile vacuole. Membrane; Lipid-anchor. Note=Endosomal pathway and the contractile vacuole membrane system.
Protein: MURB_CERSK
Sequence: MMPPVRGTLTEGRILADLTWLRVGGPADWLFQPADEADLEQFLAALDPAVPVFPMGVGSNLIVRDGGLRAVVIRLGRGFNAIRIEGDRVIAGAAALDAHVARRAADAGRDLTFLRTIPGSIGGAVRMNAGCYGSYVADHLIEVRAVTREGRAVILPAAELGLAYRQSALPEGCVLTEATFRAEAGDPAELARRMEEQIARRDSSQPTRERSAGSTFRNPAGFSSTGRADDTHELKAWKLIDEAGMRGARRGGAQMSEMHSNFLINTGGATAADLEGLGEEVIKRVFQSSGIRLEWEIMRVGELPVNKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR1_CUPTR
Sequence: MPTATPATAPVTTTDVLIVGAGPVGLFAAFQAGVLGLKCELIDVLDRAGGQCTELYPEKPIYDIPAVPGCLAQDLVDRLLEQCAPFDFPMHFGQRAESVAEIPAPAASAGHAGHERLLVTTDGGKRFDVAAVLICAGAGAFAPQRVSLPEAAALEGRHVHYAVRDVSHFAGKRVIVAGGGDSALDWALALRKVAARVTLLHRREGFRAADGTVAEMRRAVAEGEMDFVVGMLGALRTEGADGGLSEVEVRTRDGSTVLPAEELVALYGLVSEPGPIAQWDLDMRAGRILVDTTTYESSRRGIFAAGDIAFYPNKQKLILSGFHEAALALRKAYHYAFPEKALVHVHTSNNAALKEKLTHA
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RBFA_CERS5
Sequence: MGRMAHRSHTGTGPSQRQLRVGELIRRTLADVLNRGEIHDPDLNRMSITVGEVRCSPDLKVATVHVMPLGGKDVEEAIALLSKHRGELRHHITRQMTLKYAPDLRFRPDETFDRLDETRRLFSDETVQRDIRGSGDGDED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKH3_LOCMI
Sequence: MQVRAVLVLAVVALVAVATSRAQLNFTPWWGKRALGAPAAGDCVSASPQALLSILNAAQAEVQKLIDCSRFTSEANS
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic prohormone type 3.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_CAUVC
Sequence: MSKIIGIDLGTTNSCVAIMDGKTPKVIENAEGARTTPSVVAFLEDGERLIGQPAKRQAVTNPTNTLFAIKRLIGRTASDPVVEKDKGMVPYEIVKGPTGDAWVKAHGKDYSPQEVSAFILQKMKEAAEAHLGEPVTKAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKNDGKKIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDLRIVDYLADEFKKEQGVDLRKDKLALQRLREEAEKAKKELSSTAQYEVNLPFISMNASGPLHLNIKLSRAKLEALVDDLIARTIGPCEQALKDAGLKKSDIDEVILVGGMSRMPKVQQAVQDFFGREPHKGVNPDEVVALGAAVQAGVLQGDVKDVLLLDVTPLTLGIETLGGVFTPLIERNTTIPTKRSQTFSTADDNQSAVTIRVFQGERPMAQDNKMLGQFDLVGIPPAPRGVPQIEVTFDIDANGIVQVHAKDKATNKEQSIRIQANGGLSDSDIERMVKEAEANKAADEKKKQLVEAKNQGEAILHSTEKALAEHGDKVGAAEKTAIETGITELKTALEGEDVEAIQAKTQALIQASMKLGEAMYAAQQGSAEGGDAKADDGVVDAEFEEVDDNKPAA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.