PharMolix/UniProtQA huggingface dataset:
Protein: RL5_SYNJA
Sequence: MPQRLQILYNTVIVPKLQKELGYTNIHQVPRLEKIVINRGLGDASQNAKALESSIAEISAITGQRPVITRAKKAIASFKIRKGMPVGLMVTLRRERMYAFLDRLINIALPRIRDFRGVSPKSFDGRGNYTLGIREQLIFPEINYDSVDQIRGMDISIVTTAETDEEGRALLKEFGMPFAS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SPH1_HALS3
Sequence: MWNVDVTCIGGIRSGEATLRPGPNIVQASNFQGKSSFLAAIQTAIGTTGLLTEDHPLMENEDDGKVTLETDEETYTVSLTRATDSDEPAISRSGTPYLTRDQDQIAARLFAVLGEDNPIRAAVREENQERLTELLKKPLETENIDLRIEALQREIKELEDEVAAAEAASADLPAAQQKVTRLQGELRDLNETRDELERKVDEETDQRALRDELTAKQSDLEREEARLERLENQVDRRKAQLDDKEAALESLDIPDSPTAEADIAEKQTRIDELAVKIDLLDDLHRSTKAIIDEGEIDLITDVERTLSGDTFSCFVCGAETTAEAVTERLNEISDRQESLREQRATLTEEVTQMQQRTREIESKRQQKAELEDEIKRLRVDIQEDQHEVRSIEATIEELQAEIEQREAEYEAAEKAGESHSAELKTIQQKIGSTETKLDRAQAELERIEAELQKRNDRQEQLETKRDELETLRQRRKQKYNELVNQFDAAMADIIGRFAPGFDGAYLDQKTDANDTVGFEINLARDGHTTDLDTLSEGERELVGIVTALAGYRTFSVGDRVPCILLDGIGQLAAEHIRHMIEYLENTAEILVTTAYPEAGSFDGETVSPEHWDVISHETAQSRDHPQITN
What is the function of this protein?
May play a role in a late step of replication.
What are the official names of this protein?
Smc-like protein Sph1.
What is the protein family that this protein belongs to?
Belongs to the Sph1/Sph2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_AVECA
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTXXXTSLDRYKGRCYHIEPVAGEENQYIAYVAXXLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPDYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGXVANRVALEACVQARNEGRDLAREGNEIIRKACKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DER_LACCB
Sequence: MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGTSEWLGKEFAVIDTGGIDLGDEPFLAQIKDQAEIAIDEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNKVDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVLAAFPSEDKSVEDDSIKFSLIGRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYENTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEKDNHTMKDFENLIRQEFQYLDYAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLNDVLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVNDPDLLHFSYERFLINQLRQAFDFSGTPIHIIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NTF2_SCHPO
Sequence: MADYNALATQFTQFYYQTFDSDRSQLSSLYREESMLSFEGAQLQGTKAIVEKLVSLPFQRVQHRISTLDAQPTGTTGSVIVMVTGELLLDEEQMAQRYSQVFHLVNNNGNYYVLNDLFRLNYG
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_LACLA
Sequence: MSSGKITQIIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKAVSVPVGEATLGRVFNVLGDVIDGGEEFAADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLEKAKSMGY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GFCE_SHIFL
Sequence: MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQYDLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPELTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQVDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADADWRNVVLTQNGVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGMTLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQLEPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN
What is the function of this protein?
May be involved in polysaccharide transport.
What are the official names of this protein?
Putative polysaccharide export protein GfcE, Group 4 capsule protein E homolog.
What is the protein family that this protein belongs to?
Belongs to the BexD/CtrA/VexA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PURA_RUMCH
Sequence: MAVRVVVGTQWGDEGKGKYIDMLAEQSDIIVRFSGGNNAGHTIVANGVKYALHLIPSGILHTDKTCIIGNGVVVDPAVLLQEMKGLNERGVTTDHLLISDRAHLVMPYHKELDVLQEKFRGSDSIGTTKRGIGPCYVDKIERSGIRMCDLIDENEFIRKVKANLKLKNLIIERVYGGEPFEAEPIIKEYLGYAEQLKKYITDTTCILADAVDEGKNILFEGAQANFLDVDFGTYPYVTSSNPIAGGVCTGSGLGPVYVDEVYGVLKAYTSRVGAGPFPTEQNNEIGDTIRELGLEYGTTTGRPRRCGWLDTVMIKYTAKINSLTALAINHVDTIGKLKEIKLCVGYKKDGQIIRTFPASLNELAKCEPVYEVFEPWNEDISNVKLFSDLPQNAQKYLNRIEELVGVKIGLIGVGKDREQIIKVF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTLL8_HUMAN
Sequence: MEPERKGLSLASSSDGDGREENKLKQGISQDLASSSRLDRYKIARQLTEKAIKEKKIFSIYGHYPVVRAALRRKGWVEKKFHFLPKVIPDVEDEGARVNDDTCAKVKENQEMALEKTDNIHDVMSRLVKNEMPYLLWTIKRDIIDYHSLTYDQMLNHYAKTASFTTKIGLCVNMRSLPWYVPANPDSFFPRCYSLCTESEQQEFLEDFRRTMASSILKWVVSHQSCSRSSRSKPRDQREEAGSSDLSSRQDAENAEAKLRGLPGQLVDIACKVCQAYLGQLEHEDIDTSADAVEDLTEAEWEDLTQQYYSLVHGDAFISNSRNYFSQCQALLNRITSVNPQTDIDGLRNIWIIKPAAKSRGRDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKLDSAIHLCNNAVQKYLKNDVGRSPLLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVAVDRSCDIGNFELLWRQPVVEPPPFSGSDLCVAGVSVRRARRQVLPVCNLKASASLLDAQPLKARGPSAMPDPAQGPPSPALQRDLGLKEEKGLPLALLAPLRGAAESGGAAQPTRTKAAGKVELPACPCRHVDSQAPNTGVPVAQPAKSWDPNQLNAHPLEPVLRGLKTAEGALRPPPGGKGEGTVCSRLPHHGHHVAACQTTGTTWDGGPGVCFLRQLLASELPMGPGLPRDPRAPPCLVCRGLLPPAGPCKRCRSFCAAVLQGASFVRLGGRSCSPRTP
What is the function of this protein?
Monoglycylase which modifies both tubulin and non-tubulin proteins, adding a single glycine to the gamma-carboxyl groups of specific glutamate residues to generate monoglycine side chains within the C-terminal tail of target proteins.  Not involved in elongation step of the polyglycylation reaction.  Preferentially monoglycylates alpha-tubulin over beta-tubulin.  Together with TTLL3, mediates microtubule glycylation of primary and motile cilia, which is essential for their stability and maintenance.  Together with TTLL3, glycylates sperm flagella which regulates axonemal dynein motor activity, thereby controlling flagellar beat, directional sperm swimming and male fertility.  Monoglycylates non-tubulin proteins such as ANP32A, ANP32B, SET, NCL and NAP1.
What are the official names of this protein?
Protein monoglycylase TTLL8, Tubulin--tyrosine ligase-like protein 8.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: CLU_NEOFI
Sequence: MAQTNGDMEHSKGWSGHFADFSTAQFRRPRSVCSSDETNGSFFLLQRLPKPNQSNSPPMVNRLKDSRKRRAAVVCRIRDTRDGWFSALVLSSLTSSVIGLFQISVKLPHEPYKIQVMVSSQEQVQDVRQSIVELPGTFQYTCFHLEFNGKRINDFVELSEVEGLKADSEIVLVEDPYTEKEARMHMVRIRDLVGAAGDRSDNLHGLNAGLSLHDAVTAEAAADDVKEHSLSKYDITASPSLETILPRVEAPLPKTVKSISLSAWNPPPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFYVNKCSNHKFDPLPRTTPKKVSAHSLLTLISKLSPSFNSAFEALQESNNKKDLLTTFPFQNAIPNSPWLVTPPSSNPNSHQADITRSQESYLVSGVDNAETLRDWNEEFQTTRELPRETVQDRVFRERLTSKLFADYNEAAARGAVLVARGEVAPLNPTEDRDAQIFVYNNIFYSFGADGVGTFVSEGGDEAARVAVGKDVLGIKAVNQLDINGLFTPGTVVVDYLGKRIVGQSIVPGIFKQREPGEHQIDYGGVEGKDVVATHPDFVSVFEKMSKALRIKKHPVWDKEGKRHELEGSVETKGLLGTDGRKYVLDLYRVTPLDVTWQEEPGSEDYPHRMSVLRLELVEAYWRSKMSQYVKAEVERRRAAKAQEEAANKEQSSEVTESKEQESEEKAEEALDQERVDISGFQLALNPDVCSGQVPQTEEEKKQWAEDEKEVRDACEFLRSKVIPELIQDLHDGDVGFPMDGQSLSQLLHKRGINIRYLGKLAQLSKEKGSRLEALTTLLVQEMIARAFKHIANRYLRNVPAPFVASCVAHLLNCLLGADVNPNPSAEIDASLREIYPEGDFSFEKVTPETLRAEVEKQVTVRYRYTLEAEWFASLRHLQVLRDIAIKLGLQLGARDYAFTKAQLPAKVPVANGVNGASHDEGKKKKKKGGDSKSPSRAVVEEKPVISIVPDDIVNVVPLVKDASPRSSLAEEALEAGRISLMQNQKQLGQELILESLSLHEQIYGILHPEVAKLYHQLSMLYYQTDEKEAAVELARKAVIVTERTLGVDSADTILAYLNLSLFEHASGNTKAALVYIKHAMDLWKIIYGSNHPDSITTMNNAAVMLQHLKQYSDSRKWFEASLAVCESLFGKQSINTATILFQLAQALALDQDSKGAVGKMRDAYNIFLNQLGPNDRNTKEAETWLEQLTQNAVSIAKHAKDIQARRLRRINMNPRVTTLGTKVQPQVGQTAPEASGAKGAANASMDSRSIDELLKFIEGGDATSSRSKQKKRAAASNPKLRGSKKSSA
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNE_SALNS
Sequence: MIGVILVLASLLSVGGQLCQKQATRPLTAGGRRRHLMLWLGLALICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVPPRHWLGVALIISGIIILGSAA
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF1_MYCCT
Sequence: MAKETEMEFEGTVVEVLPNAQFKVKLENGVVINAHVSGKIRMHYIRILPGDKVTIVISPYDMTRGRITYRKIGK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1A2_METBF
Sequence: MANYRSTIRHRNSGSRKSVSGDTHEVTRVRTPQKDRNEVLATVLNLLGSKRVTLQCMDGVVRMGRIPGSKKKRMWIREGDIVIANPWEIQDSKADVTWKYTRPQVEWLERKGYLN
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A 2, aIF-1A 2.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: T2SM_SERMA
Sequence: MSRDDQLFTLWGKLNDRQKDNFLKWMKAFDVEKTYQKTSGDIFNDDFFDIFGDRLITHHFSSTQALTKTLFEHAFNDSLNESGVISSLAESRTNPGHDITIDSIKVALKTEAAKNISKSYIHVSKWMELGKGEWILELLLERFLEHLENYERIFTLRYFKISEYKFSYQLVEIPKSLLLEAKNAKLEIMSGSKQSPKPGYGYVLDENENKKFSLYFDGGAERKLQIKHLNLEHCIVHGVWDFILPPP
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CCCGGG-3' and cleaves after C-3.
What are the official names of this protein?
Type II restriction enzyme SmaI, R.SmaI, Endonuclease SmaI, Type-2 restriction enzyme SmaI.
Protein: RL24_XYLFM
Sequence: MASRIKKGDQVIVIAGKDKGKQGEIIRIDGHRVVVSNVNIVKRHTKPNPQRGISGGLIDREAPIHVSNIQILNPMTGKGDRVGFKILDDGCKLRIFRSTGEVIGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RNF13_CHICK
Sequence: MLLSIGMLMLSATQIYTIVTVQLFAFLNLLPVEADILAYNFENGTQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIAPPPLRDNSSTAFIVLIRRLECNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEILKKIDIPSVFIGEASANSLKEEFTYEKGGHVVLIPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSETDSSQEENEVSENTPLLRPLASVSTQSFGALSESHSHQNMTESSEYEEDDNDNIDSSDAESGVNEESVVVQLQPNDERDYRVTNTV
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates cell proliferation (PubMed:20015074).  Involved in apoptosis regulation.  Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF13, C-RZF, RING finger protein 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Nucleus inner membrane; Single-pass type I membrane protein. Note=Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.
Protein: SUFS_ECOK1
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_SYNS9
Sequence: MTIGVVVFPGSNCDRDVQWATEGCLNLPTRRLWHEETDLSGLDAVVLPGGFSYGDYLRCGAIARFAPVLQSLMDFASKGGRVLGICNGFQVLTELGLLPGALTRNQNLHFICEDAPLHVSSTRTDWLKAYGNAASLVLPIAHGEGRYQCSNDTLKQLQDQDCIALRYGSNPNGSVDDIAGITNPSGNVLGLMPHPERACDPATGGTDGRSMLKALLN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_TRIL1
Sequence: MIEINFDKMGGLIPAVIQDYENGEVLMVAFMDKKTLDLTLRDGKTWFFSRTRNKYWMKGEESGNTQDVMEVLTDCDADTVVIKVRQNGPAACHTGNRSCFYVKWEDGQWVEHSNPLFNPEEVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_STAA8
Sequence: MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FOSL_DROER
Sequence: MTLDNYNIFNDEYLFNMPLSPLPKVLGSFEAQSVLTLTTPTLTPTTTRNIEDTIGHLLSDTQADRGAGCAGFAVPKVLPNAMGAIEALGMGIPSGVTTIPIQTSYDMSLAQASESEDSNASYNDMQMNEEQDTTDTSSAHTDSTSYQTGHIMAGSVNGGGANNFTNVLAAVNSSRGVASAGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGDAMRKEIEALTNSKSELEYLLIAHRSTCQKIRSDMLSVNTCNGLIAPTGLLSAGSNGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPSANIESLMLHIKDEPLDSTIDSGSSLDQNGPPPSKRVTLPPMSTMPHMSTLMTPTGASSGSLQTPITSTAPVAFGSAFPVTTNGSSINCITINSISNNNMNSPTLNALNKVPKERPNTLAFQRPMAQMHLTLPNNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL
What is the function of this protein?
Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'.  May play a role in the function or determination of a particular subset of cells in the developing embryo.  It is able to carry out its function either independently of or in conjunction with Jra (By similarity).
What are the official names of this protein?
Transcription factor kayak.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_WOLPM
Sequence: MKKVKTVSKSKKEFITGVVHIRATFNNTFVNVTDVHGNTLCQTSVGACGFSGSRKSTPYAAGKAAESAAKNAMERFGMKVVSVIIRGPGFGTEAAVKAFQSCGLTVTSIADKTAIPHNGCRLRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RK20_LEMMI
Sequence: MTRVKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKMRALVSAYRDRGRQKRDFRRLWITRINAVTRENEVSYSYIRLIHNLYKRQLLLNRKILAQIAILNKNCLHIISKKIIK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EPB1B_XENLA
Sequence: HRVYVEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSNIDNKISTFWNESPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRSGFYLAFQDYGACMSLLSVRVFFKKCPSVVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGKCTCKAGYEPENHVVCKACPAAMFKANQGMGICAQCPANSRSTSEASPICICRNGYYRADFDTPEAPCTSVPSGPRNVISIVNETAITLEWHPPRETGGRDDVNYNIICKKCQSDRRGCSHCDDNVDFVPRQLGLTDTRVFISNLWVHTPYTFEIQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIMHQVKATMKSITLSWPQPEQPNGIILDYEIRYYEKDHHEFNSSLARSQTNTASIEGLRPGVVYVVQVRARTVAGYGKFSSKMCFQTLTEEDYKSELREQLPLIAGSAAAGVVFIVSLVAISIVCSRKRTYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIRYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFGEIVNTLDKMIRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSGFTSLHVVAQMTSEDLLRIGITLAGHQKKILNSIQSMRVQISQSPTSIA
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  May play a role in axon guidance during nervous system development.  May also play an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation.  More generally, may play a role in targeted cell migration and adhesion.  Upon activation by ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 1-B, Tyrosine-protein kinase receptor XELK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: YCIB_CHRSD
Sequence: MKMLVDFLPIALFFAVYHLSDDILLATLVLIPATLAQVAFVWWRYRRVEKMQLITLALVVVMGGATVIFHDAAFIQWKPTVVNWLFAFAFLVAPLFGGKTLIERMMGKAIALPAATWRRLNLAWVAFFIALGAINVYVFKTYDEATWVNFKLFGMLGLTLLFVLGQGVYLARHMPRDTLSQNDHQKDDV
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.