PharMolix/UniProtQA huggingface dataset:
Protein: NDUB8_BOVIN
Sequence: MAAARAGVLGVRWLQKAARNVVPLGARTASHITKDMLPGPYPKTPEERAAAAKKYNMRVEDYEPYPDDGTGYGDYPKLPDRSQQERDPWYDWDHPDLRLNWGEPMHWDLDMYIRNRVDTSPTPVNWNLMCKHLFGFVAFMLFMFWVGETYPAYQPVGPKQYPYNNLYLERGGDPNKEPEPVVHYEI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Complex I-ASHI, CI-ASHI, NADH-ubiquinone oxidoreductase ASHI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: RED2_COCH4
Sequence: MWKIESFLLSKLFLCIALCTAYVAFSSAMMEPGLWLLSRPIVPLNRTSTVFGLTIVAIGLSALSSWLSKLTLNNFTSDDSWDWSQEIVVVTGASSGIGAEIVRLLAELSIKTFILDPVPPDNSVLKNGSVHYYKVDITKPKEVSAAAREIQVKFSSPTVLINNAGVGLAKNLLDENETERRHLMNVNLLSQFTTVQEFLPAMIEKNHGHIVTMASSASYISSPQIVSYAASKAALVGFHEGLGIELVKRYNAKKIRTTLVFAPLL
What is the function of this protein?
Dehydrogenase; part of the Tox1B locus, one of the 2 loci that mediate the biosynthesis of T-toxin, a family of linear polyketides 37 to 45 carbons in length, of which the major component is 41 carbons, and which leads to high virulence to maize (PubMed:8953776, PubMed:20192833).  One of the PKSs (PKS1 or PKS2) could synthesize a precursor, used subsequently by the other PKS as starter unit, to add additional carbons (PubMed:16529376).  Variability in the length of the final carbon backbone C35-47 could be achieved by varying the number of condensation cycles, or use of different starter or extender units or might be due to decarboxylation of the penultimate product, catalyzed by DEC1 (PubMed:12236595).  Additional proteins are required for the biosynthesis of T-toxin, including oxidoreductases RED1, RED2, RED3, LAM1 and OXI1, as well as esterase TOX9 (PubMed:20192833).
What are the official names of this protein?
Dehydrogenase RED2, T-toxin biosynthesis protein RED2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NOC4_YEAST
Sequence: MVLLISEIKDIAKRLTAAGDRKQYNSIIKLINELVIPENVTQLEEDETEKNLRFLVMSLFQIFRKLFSRGDLTLPSSKKSTLEKEQFVNWCRKVYEAFKTKLLAIISDIPFETSLGLDSLDVYLQLAELESTHFASEKGAPFFPNKTFRKLIIALWSSNMGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQDLLLKNVGKWLALVNHDKHCSSVDADLEIFVPNPPQAIENESKFKSNFEKNWLSLLNGQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSNKNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNPAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHALDSSLWELASLMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNAESSRKLKTLPTLEFEAFTNVFDNEDGDSEASSQGNVYLPGVAW
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.  Its subcellular location and association with pre-40S subunit are unaffected by RPS19 disruptions, suggesting it acts before the ribosomal protein.
What are the official names of this protein?
Nucleolar complex protein 4, U three protein 19, U3 small nucleolar RNA-associated protein 19, U3 snoRNA-associated protein 19.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NSP2_ROTHT
Sequence: MAELACFCYPHLENDSYKFIPFNNLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETVMFNKVAVLICEALNSLKVTQSDVANVLSRVVSVRHLENLVLRKENHQDVLFHSKELLLKSVLIAIGQSKEIETTATAEGGEIVFQNAAFTMWKLTYLDHKLMPILDQNFIEYKITLNEDKPISDVCVKELVAELRWQYNRFAVITHGKGHYRVVKYSSVANHADRVFATYKNSAKSGNVIDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKKLLFQNMKQEKKPFKGLSTNRKMDEVSHVGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RL22_SALPA
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HMGA1_CANLF
Sequence: MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ
What is the function of this protein?
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA.  It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts.  They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (By similarity).
What are the official names of this protein?
High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1.
What is the protein family that this protein belongs to?
Belongs to the HMGA family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TSAD_NOSP7
Sequence: MTTVLAIETSCDETAVAIVNNRKVCSSIVTSQIPVHQQYGGVVPEVASRQHLETINVAIAQALEQAQLDWGQIDAIAATCAPGLLGALLVGLTAAKTLAMVHNKPFLGVHHLEGHIYATYLSESSLNPPFLSLLVSGGHTSLIFVKDCGNYETLGQTRDDAAGEAFDKVARLLKLGYPGGPVIDKLAQQGNPQAFALPEGKVSLPGGGFHRYDASFSGLKTAVLRLVQQLEKDGEQVPVADVAASFQETVARSLTKRAIACALDYGLDTIAIGGGVAANSGLRKNLQAAAVKHNLRVLFPPLKFCTDNAAMIGCAAADHLSHGHTSPLTLGVESRLALTQVMKLYHPLE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BURO1
Sequence: MKVAVLGAGAWGTALAGHLAARHDTLLWARDAALIAGLQARHENSRYLDGIALPDALRYDADLGAALAHGAADDALCVIAAPVAGLRTLCHAMRDAGCVPAHVVWVCKGFEADTHLLPHQVIAAELPEQQSNGVLSGPSFAREVGQSLPVALTVASVSAECRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGISDGLGLGLNARAALITRGLAEMSRLGVVLGGRAETFTGLTGLGDLILTATGDLSRNRTVGLQLAAGRTLNDILGALGHVAEGVRCAQAVLALARAQSIDMPITQAVCGVLFDGIAPRDAVSGLLRRDARAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Protein: DDL_PETMO
Sequence: MYIPIITGGKSKEREISLTSAKNVFNSISNLGYKPVILDLIDDDFINKIQNYKFAFNVVHGDYGEDGRLPSLLEILGIDYTCSNPETCIATYDKFIFYSLFKNYIQMPQTTLTNKLILPPFEYPFIIKPRKSGSSKGVYIIHNENEYKFYLEKDLKEFQEVLVQEYIKGREITISYIQKNEEFILLPILEIIPKKEFYDYEAKYTNGLTELKPQLNSPEKIIQKINEIGNHVMQTLTFKDMFRIDAILKDDEVYVLEINTVPGLTELSDLPTSALAAGISFDELINIIIKNHVARVAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXO1_HUMAN
Sequence: MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ
What is the function of this protein?
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity.  Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch.  Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes.  Essential for male and female meiosis.
What are the official names of this protein?
Exonuclease 1, hExo1, Exonuclease I, hExoI.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
Protein: CKAP2_HUMAN
Sequence: MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRETDAFVCRPNAALCRVYYEADTT
What is the function of this protein?
Possesses microtubule stabilizing properties.  Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner (By similarity).
What are the official names of this protein?
Cytoskeleton-associated protein 2, CTCL tumor antigen se20-10, Tumor- and microtubule-associated protein.
What is the protein family that this protein belongs to?
Belongs to the CKAP2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules.
Protein: YURN_BACSU
Sequence: MVNQNKIIPYLFLVPALVFLLFVYIPIFENVFLSLFQWSSFSPEKTFIGLKNYVELFHDPVFYQALTNNVLYAVISIVCQVFGGLILAAVLEDKLVRKWSPFFRTVFFLPVVISMTVIALLFDFIYNPETGLLNQLLQAIGLDQLTRAWLGDDSTAMLSVIFVSQWQSVGYIAMLYIVSIQKIPDELYEAARLDGAGKIQQFFHITVPQTKEMSFVAVVMTLTGAFTVFNEPYILTGGGPGKASEVLSTFLYKSAFTKDMMGYASAIATVVLIITLALSLMQMKFFKTGKEE
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YurMNO.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein YurN.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YBEY_CUPNH
Sequence: MVALLAEHTDTNQQAGLLVRPDNHDSLSVAVTATPVVTTTGTPATPPGLELEIQNGDGVGKRAGLPPRRKIETWVKSALYADAALTIRFVDEEEGRTLNRTYRGKDYATNVLTFAYAENEEDPVTGDIVLCCPVVETEAREQRKPLEAHYAHLIVHGVLHAQGYEHEEDAEAEEMEAIETETLQALGYADPYQGDRTV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFB_VIBPA
Sequence: MSTILIAIIALAVLAAIFGAILGFASIRFKVEADPIVDQIDAILPQTQCGQCGYPGCRPYAEAIANGDNINKCPPGGQATIEKLADLMGVEPEESAHDLDSKVPTVAFIHEDMCIGCTKCIQACPVDAIVGGTKAVHTVIKDECTGCDLCVAPCPTDCIEMIPVETTTDSWKWQLNAIPVVNITDAASDAANVKDSIK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: GLPK_KLEP3
Sequence: MTDKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEALAKADINSDQIAAIGITNQRETVVVWERETGKPIYNAIVWQCRRTAEICEQLKRDGMEEYIRKATGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHELDWDDKMLDALDIPRAMLPEVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVTSTHGLLTTIACGPRGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRALAWEEHDEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: FLIW_LYSSC
Sequence: MKIATKFLGEVEIANQDILTFEHGLLGLEEERKFVLLPIDADLPLALLQSVQHVEIGFVVAYPFAFKKDYSFDISEEDREQLQIEKQEDVLAYAIVTMKETFQDSTINLLAPVILNIAKKRGKQIVLQDNKAFPLRYPMQPLEGSAK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_LEIXX
Sequence: MPRIPSPPQAGLRARAARAFRLELTHPFRHDLLGVDQVADGFEFFTDRSVVAMRVNGELKDLATIVTTTDVVEPVTIYSPDGLAILRHSTAHVLAQAVQTVNPEAKLGIGPPIADGFYYDFDVAEPFTPEDLKALDKEMSRIQRAGQRFVRRVVTDEEARAELAGEPYKLELIGLKGSDAESAEVGGEESVEVGSGELTIYDNVDPKTGETIWKDLCRGPHLPNTRMIGNGWALTRVAAAYWRGSEKNPQLQRIYGTAWPSKDELRAYQTRMEEAAKRDHRKLGVELDLFSFPDEIGSGLAVFHPKGGIIRKEIEDYMRDRLIANGYEMVNTPHITKGHLFETSQHLNWYREGMFPPMHLDEERDAEGNVTRQGQDYYLKPMNCPMHNLIFRSRGRSYRELPLRLSEFGTVYRYEKSGTLSGLTRVRGLTQDDAHIYVTEEQIRDEFARQLQFVLETLRGYGLTDFYLELSTKDPEKYVGSDESWETATETLREVAVESGLELVDDPGGAAFYGPKISVQARDAIGRTWQLSTVQLDFNQPELFELEYNAADGTRKQPAMIHRALLGSIERFFAILLEHHAGAFPVWLAPTQVVGIPVADAYGPFLDDVIAQLRARGVRAEVDHSDDRMQKKIRTHTKAKVPFQLIVGEEDASAGTVSFRFRDGTQLNGVAVDEAIERIVASIQTHELVDTAWPA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACAP_RAT
Sequence: MVLDSGTQVYEQAPPSPPASSPSQHHKLKPSNRNGPPLYPWPQSLAMPLALAVPSALQHQTMWQTFSKLHLEQRSHMKRSESTYSVNSTGRRGRGKAPLGRGCDPGGGTLRPAASLPHIAKIRKDVVSGSNKSPCMLVALRPTNMDQEREKFFQSHYAYNPQFEYQEPMPMSVLEKYQEASGQFMHQAVGIIKAVLEKFGTYENFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLEQYVQDEDVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFQLLTSLGKVSYEDVEQLRPHGVLDKTRVPHFMKDLDRYRQQLEHIMTTNRLDEAELGRLLPD
What is the function of this protein?
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function.  Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8.  Recognizes adjacent tubulin dimers along the same protofilament.
What are the official names of this protein?
Microtubule-associated tyrosine carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase MATCAP family.
Protein: LHB_ROSDO
Sequence: MADNTDLSFTGLTDEQAQELHSVYMSGLFLFAAVAVVAHLATYIWRPWFG
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-870 beta chain, Antenna pigment protein beta chain.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: EFPL_ECO55
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: H2BFM_HUMAN
Sequence: MAAASAMAEASSETTSEEGQSIQEPKEANSTKAQKQKRRGCRGSRRRHANRRGDSFGDSFTPYFPRVLKQVHQGLSLSQEAVSVMDSMIHDILDRIATEAGQLAHYTKRVTITSRDIQMAVRLLLPGKMGKLAEAQGTNAALRTSLCAIWQQRK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type F-M, Histone H2B.s, H2B/s.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y604_METJA
Sequence: MNEEKAIKEFVNALKSKYRGRIKKIILFGSYARGDYTEESDIDILIVGDVDFDYVIDLCTKLLLKYGVVINAIVESEELFNKKINWSFHRNVLEEGRVLY
What is the function of this protein?
Putative antitoxin component of a putative type VII toxin-antitoxin (TA) system.  Its cognate toxin might be MJ0605, which it might AMPylate.
What are the official names of this protein?
Putative protein adenylyltransferase MJ0604, Putative antitoxin MJ0604.
What is the protein family that this protein belongs to?
Belongs to the MntA antitoxin family.
Protein: UPP_CLOBL
Sequence: MSKVTQIAHPLILHKLALIRDKNTGSKDFRELVEEVAMLMAYEVTRDLQLKEVEIETPICKTKCKMLSGKKVAIVPILRAGLGMVGGMTSLIPAAKVGHIGLYRDEETLKPVEYFCKLPQDIGDRDVIVTDPMLATGGSAKDAITLLKQKGAKHIRLMCLVAAPEGIKEVMDEHPDVDIYVASVDEKLNEKGYVVPGLGDAGDRLYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NOG1_KLULA
Sequence: MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFNITRIRAFYMRKVKFTGEGFVEKFDDILKGFPNINDVHPFHRDLMDTLYEKNHFKVSLAAVSRAKTLVEQVERDYTRLLKFGQSLFQCKQLKRAALGRMATIVKKLKDPLVYLEQVRQHLGRMPSIDPNTRTLLICGYPNVGKSSFLRCITKADVEVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTDEMNNVEMQSIYAIAHLRSTVMYFMDLSEQCGFSIEAQVKLFHSIKPLFANKSVMVVINKTDIIKPEDLDEERKKLLDTVLEVPGVEIMTTSCHEEDNVMAVRNKACEKLLASRIENKLKSQARITNVLNKIHVAQPQKRDDGIDRTPYIPEAIAKMKKYDPEDPNRRKLAKEIEIENGGAGVYNVNLKDKYLLEDDEWKNDVMPEILDGKNVYDFLDPEIAIKLQALEEEEERLESEGFYESDEEETYEGFDADEISEIREKAEWIRDRQKKMINASRNRKALKNRGTMPRSKLAKTYGDMEKHMSSLGHDMTALQDKQRVAAEKNRYEQTGADVVYGDQEDSAPAGKLRQTDRLTDGVADGSMRSKAERMAKLERRERNRMARAGESDRHATASLPKHLFSGKRGVGKTDFR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RCF1_YEAS7
Sequence: MSRMPSSFDVTERDLDDMTFGERIIYHCKKQPLVPIGCLLTTGAVILAAQNVRLGNKWKAQYYFRWRVGLQAATLVALVAGSFIYGTSGKELKAKEEQLKEKAKMREKLWIQELERREEETEARRKRAELARMKTLENEEEIKNLEKELSDLENKLGKK
What is the function of this protein?
Cytochrome c oxidase subunit required for growth under hypoxic conditions.  Involved in the assembly of the Complex III-Complex IV supercomplex, as well as in the recruitment of COX13 and RCF2 into cytochrome c oxidase.  May also be required for late-stage assembly of the COX12 and COX13 subunits and for cytochrome c oxidase activity (By similarity).
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial, Altered inheritance of mitochondria protein 31.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.