PharMolix/UniProtQA huggingface dataset:
Protein: PB2_I78A3
Sequence: MERIKELRDLMSQPRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVEILRQNPREEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTILYNKMEFEPFQSLVPKAARAQYSGFVRTLFQQMRDVLGTFDTVQIINLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGIPILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DPCKG_NITMS
Sequence: MKIPLGILLSENQADKENILKHLEENSYIITVGDRTTEKMIDFDLIPSLQIVDGIEKREKREPPKLVNTTEITVDNPPAEITSQSIDVIKKAFSMESPVRILVTGEEDLLVLPVCIHAPENSVVMYGQPNEGLVIVKITSEIRNKVQSLLDLME
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: LEXA_CLONN
Sequence: MSRSSEDKQIEIYEFIKEQIIEKGYPPSVREICKGVGLSSTSSVHGHLSKLEKKGLIRRDSTKPRTIEILKEPIVPKEMVNIPILGKVTAGTPILAVENIEDTFPISLNFIPSNKDLFMLKISGESMIDAGILDGDLAIIEKTNTAKNGEIVVALIDNEVTLKRFFKEDKHIRLQPENKNMDPIILEDDSVSIVGKLAGIFRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: WSL17_SCHMA
Sequence: MYSTKCIQKQAHKEGIWCCTWGENRNRNKQYIITGSLDNGLIAWEWTNSQLKCLYQFEGHRLGVISVDINSTGTLAASSSLDSQILLWDLETGRLTKTYDGDPADTWTIAFSPDSRFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVSICDLETGSVQFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSVDFASDNRHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSPQGNNIISVGDDRSIMIYQCA
What are the official names of this protein?
WD repeat-containing protein SL1-17.
Protein: DLDH_ECO57
Sequence: MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes, Glycine cleavage system L protein.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_STRSV
Sequence: MGIRVYKPTTNGRRNMTSLDFAEFTTSTPEKSLLVSLKSKAGRNNNGRITVRHQGGGHKRHYRLIDFKRNKDAVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLVHNIELKPGRGGELVRAAGASAQVLGQEGKYTLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: AMA2_ALLMI
Sequence: MALENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRAMHMKEYPNYKYRP
What are the official names of this protein?
SRY-related protein AMA2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPH1_VANPO
Sequence: MQAGNNGGAKLKNDEFDNLYQKNINRRETETVIRRSIPVQRDLTGKILPNQVAYYEEIEREVTFGATHHILDKDNFDSYIYPTNFEVREYQFNIVQKSLYQNTLCAIPTGMGKTFIASTVMLNFFRWSKNGKIIFTAPTRPLVAQQIKACLGITGIPHDQAAILLDKSRKNREDIWTQKRVFFTTPQVIENDLKRGVLNPKDIICLVFDEAHRATGSYAYTNVVKFIDRFNSSYRILALTATPGTDIASVQEVVNNLNISNIEIRTEESMDIIRYMKKRYKEKIEIGLTTEIEMIIEQLGIAVKPVLQQAVELGIYDECHPSQINSFVAMQKSQQIIANPTIAEGIKWRNFFILQLLNHVGQMLKRIKIYGIRSFYGYFRNKFSEFTTKYNMGKSTNKIAASFYYHPILKILMKNCDVYTSNSSFIGHDKLQKIINELSDFFLNSRLDSRVIIFTELRESALEIVKTIDNMGSSSIRPHIFIGQARGKENFDDEGFIRKNKPKGRKKADRLKRLEEDKQKQLSKAKQKEQEKVERSSRRTGSSEEAQISGMNQKQQKEVISKFKNGDYNVLVCTSIGEEGLDIGEVDMIICFDTTGSPIKNIQRMGRTGRKRDGKILLLFSGNESRKFEKAMEDYYDLQRLIGQNFVEYKKSDRILPSNITPECRKEFIHISAENNELNNMEDSDEVIRYATQCMLGKVPKSKKSKAKAAKEPKGKSKTFFMPDNVETGIVSAIALVNKKKSNSNESETVIKTECFPNLDDIEKDMLASLSSPVKPEVDDYKDGTFQKTDRFEEKITGSNLKDMLMSFSKRDEESKVTSFSSDGNYVNEPFGNISLGEKLDINDDFASTPIVKADMNIGQYDRSLIENNSRGGVLFKNAFEKEEGLLKKSEKVYFRDHYSIDNTVVIEPIPNFKRYNKSCLINHNPQVENILNLFKGINENKTQITIEMNRSRCIARGIEKGSIQLTGSDFSLANVMVAQKNNEADIVWDTSKTNKNSHENLNELLDSDSDF
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase MPH1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUCM_HISS2
Sequence: MLKGIHPAISPDLLKILAEMGHGDELVLSDAHFPAHQLHHKVVRADGISINSLLTGITPLFEFDTYTEAPLIMMQAVEGDSLDPAVEQSYLQTIKSAVGNVPKLARMDRFAFYERAKQAYAVVITGETAKYGNIIIKKGVTPVK
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP7_ROTEL
Sequence: MYGIEYTTILTFFVSFIILDYTIKTLTRAMDFIIYRFLLVVVILSPLLTAQNYGINLPITGSMDTAYANSTQEENFLVSTLCLYYPNEVVSELNDDSWKNTLSQLFLTKGWPTGSVYFNEYSDIASFSINPQLYCDYNIVVVKYSTELQLDISELANLILNEWLCNPMDITLYYYQQTDETNKWISTGTSCTVKVCPLNTQTLGIGCLTTDTETFEEVATLEKLVITDVVDGVNHKINLTTATCTIRNCKKLGPRENVAIIQVGRSSTIDITADPTTMPQTERMMRINWKKWWQVFYTIVDYVNQIIQVMSKRSRSLDAAEFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: MTA_BACSU
Sequence: MKYQVKQVAEISGVSIRTLHHYDNIELLNPSALTDAGYRLYSDADLERLQQILFFKEIGFRLDEIKEMLDHPNFDRKAALQSQKEILMKKKQRMDEMIQTIDRTLLSVDGGETMNKRDLFAGLSMKDIEEHQQTYADEVRKLYGKEIAEETEKRTSAYSADDWRTIMAEFDSIYRRIAARMKHGPDDAEIQAAVGAFRDHICQYHYDCTLDIFRGLGEVYITDERFTDSINQYGEGLAAFLREAIIIYCDHQENPRP
What is the function of this protein?
Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter.  Stimulates also the expression of the mta gene itself, ydfK and ymfE.
What are the official names of this protein?
HTH-type transcriptional activator mta, Multidrug transporter activation protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_SYNY3
Sequence: MTITFQAVIAKLNEFWAQQGCLIAQPFDTEKGAGTMNPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRVQHYFQYQVLIKPSPDNIQEVYLDSLRALGIQPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGIDCRPVSIEITYGLERLAMYLQNVEAIDQIQWNEKLSYGDIFWQGEVEQCTYNFEASNPDLLFQLFALYEQEAGQLIERGLALPSLEYVLKCSHAFNLLDARGVIAVTERTRYIGRIRNLAREVAHIYLQQREALGFPLDKKVDKPISLV
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_SHESH
Sequence: MISMNNDTLAVIKQSIKTIPDYPKPGILFRDVTSLLEDHTAYKATMDILVEKYKDQGFTKVVGTEARGFLFGAPLALELGLGFVPVRKPGKLPRETISESYELEYGHDVLEIHVDAINENDKVLVIDDLLATGGTIEATVKLIRNLGGKVNHAAFVISLPDLGGEKRLQAMDLELVKLCEFDGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2986_ALIFM
Sequence: MGRSFEVRKASMAKTQGAKIKVYSKYGKEIYMCAKNGGADPDMNLSLKHLISKAKKDQVPAHVIDKALDKATGGGGEDYQHARYEGFAPGGASVIVDCLTDNGNRTFQDVRQCFVKTGAKIGSPGTSAHMFDHQAVFQFKGDDEEAVLEALMMQDADVTDIELEDGVITVFAPNTEFFKVKTALAAEYPDLVLDVEEITFVPQNHTPVTGEDAEKFQKFLDMLDDCDDVQQVYHNAELED
What are the official names of this protein?
Probable transcriptional regulatory protein VFMJ11_A0186.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10AC_HUMAN
Sequence: MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE
What is the function of this protein?
S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.  Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration.  Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER).  Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of pro-inflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1.  Acts as a monocyte and mast cell chemoattractant.  Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation.  Can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn(2+) from their active sites.  Possesses filariacidal and filariastatic activity.  Calcitermin possesses antifungal activity against C. albicans and is also active against E. coli and P. aeruginosa but not L. monocytogenes and S. aureus.
What are the official names of this protein?
Protein S100-A12, CGRP, Calcium-binding protein in amniotic fluid 1, CAAF1, Calgranulin-C, CAGC, Extracellular newly identified RAGE-binding protein, EN-RAGE, Migration inhibitory factor-related protein 6, MRP-6, p6, Neutrophil S100 protein, S100 calcium-binding protein A12.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Note=Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation is secreted via a microtubule- mediated, alternative pathway.
Protein: RL30_SHEB2
Sequence: MATKTVKVTQTKSGIGRLPKHRATLTGLGLRRIGHTVELEDTPSVRGMINKVYYMVKVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: KAD_METAC
Sequence: MNIILFGPPGAGKGTQAKKLVDFYGIPQISTGDILRANVREGTELGLAAKAYMDKGELVPDQVLIGIIKNRLNEADCEKGFILDGYPRTVPQADALEAILDEIEKPIDVVLNLEVPDEVLVGRISGRLMCKCGASYHIISNPPKKDNVCDICGGEVFQRADDTAEAVQNRLDVYKKQTQPLINYYKEKGILVTLDGTKEIDVVFEDLKAILAKFA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_PROMA
Sequence: MATKFPSFNQGLAQDPTTRRIWYGIATAHDFESHDGMTEEQLYQKLFATHFGHLAIIGLWVAGNLFHIAWQGNFEQWVTDPLHIRPIAHAIWDPHFGQGITDALTQAGATSPVNIAYSGLYHWWYTIGMRTNAQLFQGAIFLNILVCWLLFAGWLHLQPKFRPSLAWFKNAEAQLNHHLAVLFGFSSIAWTGHLVHVAIPESRGQHVGWDNWLSVLPHPQGLAPFFSLNWGAYAQNPDSLDAVFGTSQGAGTAIFTFLGGLHPQSESLWLTDIAHHHLAIGVMFIIAGHMYRNTFGIGHTLKEITEAHNTDNPNDPHTTAKDGRHFGVNHNGIFETVNNSLHFQLGLALASLGAACSLVAQHMGALPSYAFIARDYTTQSALYTHHQYIAMFLMVGAFSHGAIFFVRDYDPELNKGNVLARVLETKEALISHLSWVTMLLGFHTLGIYVHNDVVVAFGNPEKQILVEPVFAQAIQAFSGKVMYGINALLANANSSATLAANSMPGNHYWMDMINRQDALTNFLPIGPADFLVHHAIALGLHTTALILIKGALDARGSKLIPDKKDFGYAFPCDGPGRGGTCDSSAWDATYLAMFWALNTIAWITFYWHWKHLAIWQGNVAQFNESGTYLMGWFRDYLWLNSSQLINGYNPFGVNALSPWAWMFLFGHLIWATGFMFLISWRGYWQELIETLVWAHQRTPIANLVGWRDKPVALSIVQARLVGLTHFTVGNFVTFGAFVIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RANB9_DANRE
Sequence: MSGPSSGCGFLMSVVVHGDLALNEQEKELNQRLRRLYPAVNEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAACGVYYFEVKIISKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQSQIDRFPIGEREGEWQAMIQKMVASYLVHHSYCATAEAFAKSTDQAVHEELASIKNRQKIQKLVLSGRMGEAIETTQQLYPSLLERNPDLLFMLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPGSPRLFNSPVHKPSSSQAYQTGFDSNYCNGVSSSKGHTSAHSHKSCPPTLSSPELGVLNGSRGQQTIVSSEVEMEVDHFSNGVSESSSNGFLNGSSTHGTEQEDCDADMEVDSTQSKRQLCGGSQAAIERMIQFGRELQSMSEHLRRERGKNSANKKMLKDAFSLLAYSDPWNSPVGYQLDSIQREPVCSTLNSAILETHNLPKQPPLALAMGQAAQCLSLMARTGSGSCAFASVDDYLH
What is the function of this protein?
May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways.  Acts as a mediator of cell spreading and actin cytoskeleton rearrangement.  Core component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ran-binding protein 9, RanBP9.
What is the protein family that this protein belongs to?
Belongs to the RANBP9/10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Predominantly cytoplasmic.
Protein: LGB1_MEDTR
Sequence: MSFTDKQEALVNSSYEAFKQNLSGYSVFFYTVILEKAPAAKGLFSFLKDSAGVQDSPQLQAHAEKVFGLVRDSASQLRATGGVVLGDAALGAIHIQKGVVDPHFVVVKEALLKTIKEAAGDKWSEELSTAWEVAYDALATEIKKAMS
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin 1.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: FTSZ_PSEAE
Sequence: MFELVDNIAQTAVIKVIGVGGGGGNAVNHMAKNNVEGVEFICANTDAQALKNIAARTVLQLGPGVTKGLGAGANPEVGRQAALEDRERISEVLEGADMVFITTGMGGGTGTGAAPIIAEVAKEMGILTVAVVTRPFPFEGRKRMQIADEGIRALAESVDSLITIPNEKLLTILGKDASLLAAFAKADDVLAGAVRGISDIIKRPGMINVDFADVKTVMSEMGMAMMGTGCASGPNRAREATEAAIRNPLLEDVNLQGARGILVNITAGPDLSLGEYSDVGNIIEQFASEHATVKVGTVIDADMRDELHVTVVATGLGARLEKPVKVVDNTVQGSAAQAAAPAQREQQSVNYRDLDRPTVMRNQSHGSAATAAKLNPQDDLDYLDIPAFLRRQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: TFEC_RAT
Sequence: MTLDHRLFSQTLKRAQPLAASCMPLAEHGPRSPDSDAGCAGNPFTNPLALGKEDGVVEWRLSGSILDVYSGEQGISPVNTGLMNASCPSILPMKKEIAETDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDIRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLMLRIQELEIQARAHGLPILASLGTADFGTHITKQQTHSEKNSVGCCQQLTPSQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL
What is the function of this protein?
Transcriptional regulator that acts as a repressor or an activator.  Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence.  Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer.  Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity).  Collaborates with MITF in target gene activation (By similarity).  Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity).  Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity).  Binds DNA in a homo- or heterodimeric form.
What are the official names of this protein?
Transcription factor EC, TFE-C, rTFEC.
What is the protein family that this protein belongs to?
Belongs to the MiT/TFE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAPSD_HBVC0
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHVSCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PURT_BURMS
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVIAVDRYPNAPGHQVAHRAHVIDMTDPDALRALVDAERPHLVVPEIEAIATDALAAIEAAGVCEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFAQSFDEFAAAVARIGFPCVVKPVMSSSGKGQSVLRSEADIEPAWRYAMAGGRVNHGRVIVEGFIRFDYEITQLTVRAIDPASGQTRTSFCAPIGHLQVAGDYVESWQPQPMSAKALERSRDIAHRVTSALGGRGIFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVEPALATPAASAVIYGGLDEAGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALATGANVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.