PharMolix/UniProtQA huggingface dataset:
Protein: HELS_METTH
Sequence: MKSLPPEMRQILGDCYPHIRELNPAQRSAIEAGYLESEDNYIIAIPTASGKTLLGIIAALKTVMEGGRVIYTVPLLSIQNEKIKEFRKLEEHGIRVGKDPRTSDIAVMVFESFDSLTRFSWNILREVDLLIVDEFHMIGEYTRGPVIESAITRARTLNPSVRIVALSATLSNMDEIAGWLDARVVEHDYRPVPLHREVLDTEMFGVREKNDVVLKVLERSLEDGSQTLAFVSTRRFTESLASHLADKISGKIPDDMVESFREVAGKVLEVPKSRGSPPTSTCLKLAECLEAGIAFHHAGLFNRQREIIEDEFRDGNILMITATPSLMYGVNLPSRTVVIRDYTRWTSQGPRRIPVFDYEQMSGRAGRPQYDDAGYSYLIARSHDEAMDLEEYYIRGEVERTTSRIIENRDALYRQIIAQVASGLSGTTEELADFFRNTFYGYQMVEGPFSDSFGMDSIQYEVENATEYLMRNRILYPGPEGFSATEFGLLIAKSNYSVETAIKLHQFASEMDEMDIYRLIYEITRTPDMPLISFKGRKSRDPVRDKLMEHGLFLMDVGNEEATAAALIEWINERTEYEIENAFHVYAASTRRSAYEASKIVKFFGKICEIMGVYRHSSQLEILSARLYYGVKEDAIPLVVGVRGLGRVRARKIIKTFGEDLRHVREDELKRIDGIGPKMAGAIRRYCERF
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.  Helicase with 3'-to 5'- polarity; able to unwind over 100 bp of DNA at 50 degrees Celsius.  Unwinds forked DNA, preferentially on lagging strand forks; has weaker activity on Holliday junctions.  Displaces the invading strand in DNA D-loops.  Unwinds short oligonucleotides from dsDNA with 3'- but not blunt ends or 5'-ssDNA tails in an ATP-dependent manner.  ATPase activity is stimulated by ssDNA but not dsDNA, protein binds ssDNA, dsDNA with 5'- or 3'-overhangs but not blunt ended dsDNA and replication forks.  Replication forks bind both this protein and RPA.  RPA does not stimulate the helicase activity of this protein.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: DCAM_PEA
Sequence: MAVSAIGFEGFEKRLEISFSDPGLFSDPQGRGLRSLTKSQLDEILAPAECTIVSSLANEDVDSYVLSESSLFVYAYKLIIKTCGTTKLLLSIPPILKLADSISLNVRSVRYTRGSFIFPGAQSFPHRHFSEEVAVLDGFFGKLGSGSMAYILGGSDEAQNWHIYCASSDSVSPEGSVYTLEMCMTGLDREKASVFFKEQTGSAAEMTVNSGIRKILRNSEICDFDFEPCGYSMNSVEGSAVSTIHITPEDGFSYASFETAGYDLKAINLNEMVMRVLACFQPTEFSVAVHVDNASKSFEQGCLLDVKGYCCEEKSHQGLGMSGSVVYQKFLKTSYCGSPRSTLKCWKDEDEEE
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: GP_PUUMU
Sequence: CQFDGNTISGYKRMIATKDSFQSFNVTEPHISASALEWIDPDSSLRDHINVIVSRDLSFQDLSETPCQIDLSTASIDGAWGSGVGFNLVCTVSLTECSAFLTSIKACDAAMCYGSTTANLVRGQNTIHIVGKGGHSGSKFMCCHDTKCSTTGLVAAAPHLDRVTGYNQADSDKIFDDGAPECGMSCWFKKSGEWILGVLNGNWMVVAVLIALLILSILLFTLCCPRRPSYRKEHKP
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion.  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.
What are the official names of this protein?
Envelope glycoprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein.
Protein: FPG_TRIV2
Sequence: MPELPEVETVRRGLNQLTLNRKITGGDVLLHRTIAHPFSVGDFLNGITGDSISAWHRRGKYLLASTTSAAWLGVHLRMTGQLLWLNQDEPLHKHTRVRIFFEDQQELRFVDQRTFGQMWWVSSGMAVESVITGLAKLAVDPFSPEFTVEYLANKLHNRRRPIKTALLDQSVVAGLGNIYADEALFKSGVLPETLCTEVQLKQIELLRTAIIQVLETSIEAGGTTFSNFLNVKGVNGNYGGVAWVYNRAGEPCKVCGDVIQRIKLGGRSSHFCRQCQV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DAPD_BLOFL
Sequence: MNENNIQKLQKIIEHYFIKQQNISKNNIDLNLRNTVQEVIDNLNNGILRVSEKINNKWITHQWIKKAIILFFTITNNKLMTWGNARFFDKCPTKFENKSEEYFKNRKIRIIPPATVRYGAYIANNTVIMPSYVNIGAYIDTGTMIDTWATIGSCAHIGKNTHISGGVGIGGVLEPIQANPTIIEDNCFIGARSEIAEGVIIEENSVLAMGVFISQSTKIYNRSTGHVHYGYVPSGSVVIPGSLPSEDGKSSTYCAIIVKTVDSRTKNKIQINNLLREYCN
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_ASPOR
Sequence: MGLSQSTELGQASSPEELSHMLAERFATKCFTPLELTHFKDNFFTRAAGQGDVKYWNEKILSDFLAIPDSSDAECPLDAGPVIFRMVSYLGAFPFQNTLAPSVLTFEAMVKVVVLLTERYGKVLRRARKDRIRLLFGSLADVGRKDIDQPANDGNSKEDKVDSSATKSHAPGFSVDEPTNDDYEDDDDDLALAALESLDAIEVFRHDSRIDKAVYEARISIATFRRLLMLLLVISPLRPLEPVKAYTSDLNEGRMRTVRQQADNILAAFPQEESGGISYRAFAKTIETSLPYLFDPLTPLFEHLLFSRNLNLSQKRDRSDSTDPTDQTSETPLPLSASIMLPGSFESAILNPSIVSHLSFFLPSTNGSKNLLRDNLRLHPIFSTAAHGSSLTSFSHNVLTWQSGTLLLLEGAVAEPSGEQMVTLGAYLPQPWKTGSSAQSSRLSETSALPCLFQLSPKHLLLPGNPSSSIQNPDTPAAYFSNHSGISLGCRIPPASRSQRLVPSPLGAGSLTIDTSLETAEFHVAPFGHNGVFLPAGTSSTSDNATKTHIDIYNLELWGFVPDPGVSSSEKSAIELQKAKWDFEAREAERRRSLNIKAGAGDSAMEGARWLLETAGIIGDSHGRGGGSV
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_SALPA
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWTDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEFDENFKPLKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: NRDR_MYCA1
Sequence: MHCPFCRHPDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSREKVISGVRRACQGRQVDDDALNLLAQQVEDTVRAAGSPEVPSHEVGLAILGPLRDLDEVAYLRFASVYRSFESADDFEREIQALREHRGVATPG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PANC_BACCQ
Sequence: MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDENVAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVTIVPVDIVREEDGLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVDYADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIL_HEVBR
Sequence: EQCGRQAGGALCPGGLCCSQYGWCANTPEYCGSGCQSQCDGGVGGEGGCVDLGSIISRSTFEEMLKHRNNAACPAKGFYTYDAFISAAKAFPAFGTTGDVDTCKREIAAFFGQTSHATTGGWPTAPDGPYAWGYCHKEELNQASSYCSPSPAYPCAPGKKYYGRGPIQLSWNYNYGQCGQALGLDLLNNPDLVATDRVISFKAAIWFWMTPQFPKPSCHDVITGQWSPTGHDISAGRAPGYGVITNIINGGLECGSGWDARVEDRIGFYKRYCDMFGVGYGSNLDCYNQTPFGLG
What is the function of this protein?
Probable inactive chitinase-like protein that does not exhibit hydrolytic activity toward chitin (By similarity).  May bind chitin and be involved in plant defense against fungal pathogens (By similarity).
What are the official names of this protein?
Probable inactive chitinase-like protein LaCIC, Leaf class I chitinase, LaCIC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: SUB3_ARTBE
Sequence: MGCIKVISVFLAAIAAVDARAFFHNRGGNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGWRAYNGHFDEATIESILKDDKVNYVEHDRVVKLAALTTQPNAPTWGLGRVSHKAPGNKDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDNTDGNGHGTHTAGTFAGTTYGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNALGKAALNLSLGGSFSQASNDAVTRAQEAGIFVAVAAGNDNRDAKNSSPASAPAVCTAASSTIDDQKSSFSNWGTIVDIYAPGSNILSAAPGGGTRTLSGTSMASPHVCGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_HAEDU
Sequence: MKAQELRTKNVEELKAELINLLGEQFKLRMQAATGQLQQTHQLKQVRRSIAQVKTVLNQKAGE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: MORN4_HUMAN
Sequence: MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKLLRREKCSAIVQRAQSASKSARNLTA
What is the function of this protein?
Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma.
What are the official names of this protein?
MORN repeat-containing protein 4, Protein 44050, Retinophilin.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Note=Found in the cytoplasm in the absence of MYO3A and localizes at filopodial tips in the presence of MYO3A.
Protein: ENO_THEM4
Sequence: MYIEIIDIYAREVLDSRGNPTVEVEVMLEDGSVGRAIVPSGASTGKFEALELRDKDSKRYGGKGVLKAIENVNEKIAPKLLGLNAYEQVSIDKTLLEIDGTENKSNIGANAILGVSMAVSRAVANSLQLPLYKYLGGVNAKVLPVPLMNVINGGAHADNNLDIQEFMIVPAGAPSFREALRYGAETFHALKRILKEAGHVTAVGDEGGFAPNLQNNEEAIQVLIRAIEKAGYVPGKDIYIALDVAASEFYNGETGKYFIDGTEKTSDELIEYYESLINKYPIISIEDPFDQEDWDSYRKFNEKVGKKVQIVGDDLYVTNVKRLEKGIELKATNSILIKLNQIGSVTETLNAIELAKTNNMTNVISHRSGETEDTFIADLAVATNAGQIKTGSLSRSERIAKYNQLLRIEEELGDAAEYKGIKAFYSIDR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: UBIE_BURM7
Sequence: MSKTHFGFETVEENEKAKKVAGVFHSVASNYDLMNDLMSAGLHRAWKAFTIAQANVRPGGKVLDIAAGTGDLTKAFAKAAGPTGEVWHTDINESMLRVGRDRLLDKGVVTPSLLCDAEKLPFPDNYFDVVTVAFGLRNMTHKDSALAEMRRVAKPGGRVMVLEFSKVWEPLKKAYDVYSFKVLPWLGDKFAKDADSYRYLAESIRMHPDQETLKTMMEQAGLDAVKYYNLSGGVVALHVGTKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: GPC6A_BOVIN
Sequence: MALLMTCFVIVFAASQPCQTPDDLVAAASPGHIMIGGLFAIHEKILSSEEPRKPEIQKCASFEIPTFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTDITVAMAAALRCVSKFNSSREIVEFKCDYSNYVPRVKAVIGAGYSEISMAVSRTLSLQLMPQVSYESTAETLSDKIQFPSFLRSVSSDFYQTKAMAHLIQKSGWIIGILTTDDDYGLNTLAVQTAANNVCIAFREALPAFRSDITIEVRINQTLERTIAEAKVNVIVVFLSQFHVFNLFSKAIERNINKIWIVSSWSTSTIATIPDVKRIGKVVGFTFRRGNVSSFQSFLQNLCVFPSDNNKPLNEHAMLSACAHAKDSDLSQCVSNCSQGTLATKDSERNFFLRTDFLWDYTELGLVHSIQLAVLALSYAIQDLQADFQPWELLAVLKNVTFMEGWSSFHFYAHGAMNTGYNIVLWREINGHMSIKMAQYDLKNDVFIVTNQETKNEHRNLKKIQSKFFKECSSGQMKKTTKSQHTCCYECVTCPENHYSNQTDTDHYLLYNNETHWAPVGSTMCFEKEMEYLDSLAILLLALSLLGILFVLAIGIIFTRNLNTPVVKSSGELMVRYVILFCHFLNFAGTGFFIREPQSFTCKTRQTLICMSFTLCISYILMKSLKILLAFSSKLQNFLKCFYKPIPIIFTCTGIVVVCTLLIFAAPAVGQNVSLPRVIIFECEEGSILAFGSMLGYAAILAFMCFICAFKGRKFPENYNEAKFITFGMLIYFIAWITFIPIYTFGKYMLVVEIIIILISNYGICCMFFPKCYVILSKQETNTKSVFLKMIYSYSPHSAGSLAMSHSNITITNRTSAGGSAVQQKSRDLQLQGFAHICRENAMCRTKALPPKRISSI
What is the function of this protein?
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids.  The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+).  Activated by extracellular calcium and osteocalcin.  Seems to act through a G(q)/G(11) and G(i)-coupled pathway.  Mediates the non-genomic effects of androgens in multiple tissue.  May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids (By similarity).
What are the official names of this protein?
G-protein coupled receptor family C group 6 member A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPX_GLAP5
Sequence: MMRIALFLATNFAVMIVLGIILSVTGIAGNSTGGILIMSVLFGFAGSLISLFMSKTMALKSVGAEIITEPRNNAERWLVETVKRQSQQAGIPMPDVAIYHSADVNAFATGATKSNSLVAVSTGLLNTMTEDEAEAVVAHEVAHIANGDMVTMTLLQGVLNTFVIFLSRMIATAVSSSRNDDGEETQSSGTYFLVSMVLEILFGVLATIIAMWFSRYREFRADAGSAQLVGKEKMIAALQRLQRVHDPEELPGSLNAMMINGKAKEFFMSHPPLEKRIEALRNL
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM1_MYCVP
Sequence: MSVLLFGVSHRSAPVSVLEQLSVDDSDQAKLIDQVLQSSLVTEAMVLSTCNRVEIYAVVEAFHGGLSVIGQVLSEHSGMSLQDLTKHAYVRYAEAAVEHLFSVAGGLDSAVIGEQQVLGQVRRAYASAEANHTVGRTLHELSQRALAVGKRVHSETGIDAAGASVVSVALDTAEKKVGSLAGRSAVLVGAGSMGALAAKQLMRAGVERIHVVNRTLPRAAKLAENVRSYGITAEAFPFDHLPPLLTDADIVVTCTGAVRPVVSLADVHRGLAHVREPKELVICDLGMPRDVDPAVAGLPGVFVVDMERILREPTARAAATDADAARTIVAAEVAKYLAGQRMAEVTPTVTALRQRAADVVEAELLRLDNRLPGLDAAHRDEVANTVRRVVDKLLHAPTVRVKQLAGAPGGDSYAEALRELFELDQHAVDAVAGTELGPLAGGDELGSLAIDLDMTE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RL22_METS4
Sequence: MGKAAAPRALPENEAKAVARMLRVSPQKLNLVAQLIRGKKVANALADLQFSRKRIAVEVRKCLESAIANAENNHDLDVDDLVVKEAYVGKALVLKRFHARARGRGARILKPFANLTIVVREVRAEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: OPGC_ECOLI
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAESSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_STRS7
Sequence: MTRLIFMGTPQFSATVLQGLLENPAYDILAVVTQPDRAVGRKKDITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVTFAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTDNVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPAREVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGALSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MZM1_YEAST
Sequence: MSTRTKALNAYRHGLRATRIAFRNDAEVLLAARAKMRSGMLCPPDPKLTTEDQIQHLEDVAVFLRRNLVQGKKVDGSSTKEPRYHLNIHKDTELGDNETIADPTARVKTNLKARPFKCSDKKQ
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool.
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial, Altered inheritance of mitochondria protein 8, Found in mitochondrial proteome protein 36.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: APTH1_ASHGO
Sequence: MSATAPIRIAARAQPAKYAFIIFHGLGDSGAGWTFLAEYLQRDPALASAQFVFPTAPVRPITANNFAPATAWLDVRSWLSHESVDLEGFNESMKLVPKLIEEQVAQGIPYERIWIGGFSQGAALTMGTALSFPHRLGGFLSFSGPPSYRWLEHTVSDANTGAPVFQSHGTMDEVFPSSGAEAVHRSFTSQYGFKNHRLKIYDGLGHSISPQLLDDALAFIKANLDAEKPAPRPAL
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.  Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins.  Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.
What are the official names of this protein?
Acyl-protein thioesterase 1, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: APT_YERPE
Sequence: MTVSASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIKLLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_ANACO
Sequence: MSWQAYVDDHLMCEIDGQHLSSAAILGHDSTVWAQSPNFPQFKPEEISAILNDFENPGSLAPTGLYLGGTKYMVIQGEPGVVIRGKKGTGGITVKKTNLALIIGVYDEPMTPGQCNMVVERLGDYLLEQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Minor food allergen Ana c 1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TLE1_XENLA
Sequence: MFPQNRPPTHLQASVATGAASGPPQSLKLTYPETLDRIKEEFQFLQSQYHSLKLECEKLATEKTEIQRHYVMYYEMSYGLNIEMHKQTEIAKRLNVICAQLVPFLSQEHQQQVVQAVERAKQVTMAELNAAIGVRFIPPQLTVHQLQAQHLSHHAPPIPLTPHPSSLQHPGLAAATSASSLLGYLVFLAFRHNLLQKRAADAEHRERDPGPSCLTLPNGERVPTLSDYLNSNTKRKTEEKDFGTDYGSDADRSEDNLVVDEDPASPHSVHSYSSRENGVDKPTLQRKDPPPASPNSMTSSSSVSPSRSKDIPSQQVEKAGTPGLKSSTPNSQSDLNTPGPSGTSASQFRSIATKPAIDSLALGLRTPLGGQGGYPAAFSIAHPSVNADGAGAYAGLHLMSPQINGATAAGTYGRSPLVSYDPHAHMRGLGSAIPGSASGKPAYSFHVSADGQMQPVPFPPDALIGSGIPRHARQLHVLNHGEVVCAVTISNSTRHVYTGGKGCVKVWDVGQPGTKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIVVWDLQNQTLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRCWDLREGRQLQQHDFNSQIFSLGYCPTGEWLAVGMESSNIEVLHVSKPDKYQLHLHESCVLSLQFASCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDVSTDDQFIVTGSGDKKATVYEVIY
What is the function of this protein?
Nuclear effector molecule.
What are the official names of this protein?
Transducin-like enhancer protein 1, Enhancer of split groucho-like protein 1, ESG1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: S10AA_RABIT
Sequence: MPSQMEHAMETMMFTFHKFAGDKGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFFSLIAGLTIACNDYFVVHMKQKGKK
What is the function of this protein?
Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
What are the official names of this protein?
Protein S100-A10, Calpactin I light chain, Calpactin-1 light chain, S100 calcium-binding protein A10, p10 protein.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.