PharMolix/UniProtQA huggingface dataset:
Protein: RL22_DEIDV
Sequence: MTAPTPEFRNKKQRKQQVKLRTPGKAIAKYVRMSPRKVRLVVDVIRGKSVSDAEAILRFLPKSASEPVAKVLNSAKHNALHNDEMLEDRLVITAAYVDAGPTLKRLIPRARGSANILKKRTSHITIIVGERNDTRGGKR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CTAA_METC4
Sequence: MRLSTNPTLDRFDAVPAASYRPGHGAVRAWLYLLAVLVVAMVAVGGATRLTGSGLSITEWRPVTGVVPPLDAADWAVEFDKYRDTPQYRILNQGIGLDGFKTLYWWEWGHRLLGRIVGLVFFLPFAWFWARGMLGRRLLTGLLGLGLLGGLQGAIGWIMVASGLQPGMTAVAPLKLALHLTTASLILAGLVWLAAGTRPRALAPAPESVRVVACLLPALVLVQIWLGGLVAGSKAGLLYNTWPDMDGVLVPPARVLFDKVPFIENFIDNLALVQFNHRLFAYLVVAVAIAHAIQAARTASGSAAAGRAMGVAALATAQMGLGIATLLLHVPLWAGLAHQVFAMAVLIMATVHARLARGVPAAAAPTGAEVPIGLEALAGRGA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMB_SODGM
Sequence: MKTHYNLRVIAARAVAQVLDQGQSLGALLPPLQAPLSEKDRALLQELCFGIMRVLPQLEWLLRQLMAKPLTGKQRPVHYLLMVGLYQLTYTRIPPHAALAETVEGAVAMKRPQFKGLINGVLRQFQRQQPALLADAERQDIRHLHPSWLQKRILAAWPAQYAQIIDANNQRPPMWLRVNRLHHSRDAYLALLAGTDIAAVAHSQLPDAIRLEMPCNVGRLPGFDRGWVTVQDASAQGCALLLAPQNSETILDLCAAPGGKTTHILEIAPAARVMAVDVDGQRAARIHDNLQRLGMQAEVVIGDGRTPDAWRSGMLFDRILLDAPCSATGVIRRHPDIKWLRRDGDIAELAELQRQILCAAWRVLKLGGTLLYATCSILPEENRGQIAAFLADHPDALLQETGDAAAPGLQCLPVPTSGDGFFYAKMIKETQAC
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_PSEAE
Sequence: MSLELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTRDVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCM_DANRE
Sequence: MVILKGIPSVLTPELLYVLAQMGHGDELVLADANFPTSSVCKCGPVEIRADGVRIPELLKAILKLFPLDTYDESAAVMDLVPSDLLKGLKVPIWDQYSELLKQAGSDGNMKPVERFAFYERAKKAFAVVATGETALYGNLIIKKGVIPPEEQC
What is the function of this protein?
Involved in the interconversion between alpha- and beta-L-fucoses.
What are the official names of this protein?
Fucose mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family.
Protein: RIMP_TREDE
Sequence: MEFIQKKDIPYFSECEPLVEGLGFKLVDLNVLHKKDVWQVKAVIKSEKGVGIKDCTSVHRTLQPRIEALIGSQDVTMEVSSPGINRLVKRAVEFYAFVGEEAQIWDNSITDWRHGIIKEVNSEGLVLNSDNQDIQIPYQDIKKARCNL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_PSEA8
Sequence: MSAVTQHHADELARGADELGVALDADKQRQLLAYLALLIKWNKAYNLTAVRDPDEMVSRHLLDSLSIVPYAEAGDNWLDVGSGGGMPGVPLAILFPEKRLTLLDSNGKKTRFLTQVKLELKLANLEVVHSRVEAFRPESPFDGIVSRAFSSLEDFANWTRHLGGQETRWLAMKGVHPNEELAALPEDFRVEAEHALAVPGCQGQRHLLILRRTA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAT1_CURKU
Sequence: MNLTRDPTGAEIARFIATRTGAQMVELMRCISEPAAQAAFTANLLAAPPVVDARPAASERARKALNAFVRFRCYYVAIPMFKQWPMKKLSNLIGLLWEADPNKSLWSLMTKAWSTIRDQIGKEQAPLDQFFSIICPHLRLPDPALYLEIHGWTLTVDQEGDPTISRSLNSRSSSIGTGNIDIALSVEDIIAYVQSFGYAASFTPTTNVSSPTFLGQSTNLPLENNNPTTAATQAASKIAQARLLARNKRRAKRQTAKETGYRVNLDQDILNAHQISPPPMNRYMPDPYSTFAPTPNHSPNPFYDGLTGFLSEQASIEQVNAATLHNTHSLSDSGLSGDMSYMTMDNFATNMPNLIDYDAFRLGANEDVTLPLFDDIAHA
What is the function of this protein?
Required for mating.
What are the official names of this protein?
Mating-type protein MAT-1.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYY_STRPD
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX1_CAEEL
Sequence: MNRNFSIDAILARKPVEKRKQIITKDNCKFIRVFLQSSNLWRRFHNLGTEMIVTKSGRRMFPTLSVIIAGLDPVKSYVVMVDLECIEMKRFRYSFHQSKWISTGPGESELPSRMFVHTDSPARGAHWMRAPVSFDKMKLTNNQLDNNGHIIVNSMHKYRPRVHIIEQDDSQKRHTFSFEETEFIAVTAYQNHRITSLKIESNPFAKGFRECEVQGIEMNSVGGMTGGPAFQSVFPLIFPYFANLASNMNVNK
What is the function of this protein?
Probable transcription factor required for the cell fate specification of non-striated uterine muscle precursor cells (PubMed:11799068, PubMed:21852953).  Furthermore, may function with the transcriptional corepressor unc-37 (PubMed:21852953).
What are the official names of this protein?
T-box transcription factor mls-1, Mesodermal lineage specification protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_ACAM1
Sequence: MPKLKTRRSAAKRFKRSGSGKFMRRKAYKNHLLEHKGPDRKSRLSKKCVVSEQDAENVRAMMPYS
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HUTU_BACC0
Sequence: MEKVKQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALAVANEYKEKKEPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLAMQEKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDAVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVETAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_TRYCC
Sequence: MGDIIRIKRHHYVHILDNNTNVTRCMVGPLVYTRKENERCLFNPKPCIVVPPRFYCIVQNPCVRDASGNPVIGENSSVMLRMGEEEICFEQEPFPLQPGEVLKREEEEWLFKLKLIPVNTGYHVRCLCDFTDKNSVLRRAGTEWLVEGPQTYVPRVEVEVLREVHAHIISPNTALHIRALVKFTDRTGVPREAGDLWTVRTVGAYLPAVEEDVIGTFQGITLTDTEAVHLEALSNFTDVYGKRRRAGERWLVTKEDASIHIPDVHEKVSGKVRAIVLNEKEYCVVQNPLGADGLNEFGRKEVRKGECRFFLHPQEELLGGMQPINVVSKDQALLLQAVDFFDDNGKIRRPGEKWMLHGPAEYIPDVNVRILEQRNLIALDKNEGIYVMNTTTGVVRVVIGKPYMLNENEVLWEKDLSPKVEELLAFANGCMSEGERNPSFKSTRVRHRVVRFNVQHNAAVQIYDYKQKKLRVVLGPNLVILSPDEEFTVVSLSGGKPKVPNLLHCLQLFLGPRFSSDRIVVETSDHARLELDLSYNWYFDVNREEPDAKIFSVPDFIGDCCKTIASRIRGAVAAEDFDSFHRNSAKIIRVAVFGRGENGEINTSLRFSANNLVVTNIDIQSVEPTDAKTRDSLQKSVQLAIEITTKSQEAAARHGKERKDQEARGKLERQKLLDKIEVERTKTKWLQLQAQSEAVQASGQSVAEAKAKAESLLIEVDSELKQAEMRAKAYRITAESELKKQKQKLELELEFTKRQNELDIMKARQIAETEAERVQRMVNAIGRETIVAVAQAGPEMQAKLLGGLGLKGYLITDGKSPVNLFNTAQGLIDAGSSAQEHS
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
What are the official names of this protein?
Major vault protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CSRA_HAEDU
Sequence: MLVLTRKVGESLLIGDDIEITVLSVRGNQVKLGVNAPKNIVVHREEIYHQIKALADNIPESV
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P5CR1_PONAB
Sequence: MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
What is the function of this protein?
Housekeeping enzyme that catalyzes the last step in proline biosynthesis.  Can utilize both NAD and NADP, but has higher affinity for NAD.  Involved in the cellular response to oxidative stress.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THIE_MYCBP
Sequence: MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RUVC_ACIC5
Sequence: MRIFGIDCGSEITGYGIVECPDGTPRSGQPDLRLIAFGGIRPAKKLTLAERLAFVHRELLTQLAAHQPDLVAVEEVFYSVNAKSALKLGHVRGVALLAAATAGLPIAEYAPLTIKSTVTGYGLAQKEQVQFMVARLLHMPEPPEPADAADALAIAICHIHHAQTIQAQQSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PYRC_RALPJ
Sequence: MTDTLTIVRPDDWHLHLRDGDALADVVGDTARQFGRAIIMPNLKPPVTTTAQARAYRERILAALPAGTQFEPLMTLYLTDNTSPEVIREARASGFIHGVKLYPAGATTNSDAGVTDLRRCAKTLEAMQEVGMPLLVHGEVTDPTVDIFDREAVFIDTVMLPLRRDFPALKVVFEHITTKHAAEYVRDAEGPVGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRLALVAAATSGHPRFFLGTDSAPHAKGVKEHACGCAGCYTALHAMELYAEAFEDANALDKLEGFASLHGPDFYGLPRNAGTLTLTRSQWQLPAEVPFGEQTLVPLRGGEMLRWKSV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: KV2A1_MOUSE
Sequence: DIVITQDELSNPVTSGESVSISCRSSKSLLYKDGKTYLNWFLQRPGQSPQLLISLMSTRASGVSDRFSGSGSRTDFTLEISRVKAEDVGVYYCQQLVEYPLTFGAGTKLELK
What are the official names of this protein?
Ig kappa chain V-II region MOPC 167.
Protein: SYE1_RICM5
Sequence: MTKVITRFAPSPTGMLHVGNIRAALLNWLYAKKHNGQFILRFDDTDLERSKQEYKDAIEEDLKFLNINWDQTFNQLSRLSRYDEIKNLLLDKKRLYACYETPEELELKRKFQLSKGLPPIYDRASLNLTEEQAKKYIEQGRKPHYRFLVNHELINWHDMIKGEVKYDGKALSDPIVIRADGSMTYMLCSVIDDIDYDITHIIRGEDHVSNTAIQIQMFEALNTTPPTFGHLSLIINKDEKISKRVGGFEIATLRKEVGIEAMAIASFFSLLGSSAQILPYKSMEKLANQFEISSFSKSPTIYQPEDLERLNHKLLISLDFDTVKERLKEINAEYIDENFWLSVSPNLQKLRDVKDWWEICHQTPNVENLNLDKEYLKQAAELLPKGEITKDSWSIWTKEITNITGRKGKELFLPLRLALTARESGPEITGVLPLIDREEIIKRLTSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1002_CHLCV
Sequence: MSFVKKKFHPISRYYNYLFPIAAFLLPLICLPFLSASQKNYSYFIFSIISAVGWFFSIGLREKQLKMAAGQLLQTKIRKIVEKDEGLRKICESVEERQYESQQLRSQNQKLLNQLLHVRSVFMKTKADTQRMEGAIAHLREENQCLQLQLDALSQECREKEEEAQQLNRELADALAYQQVLNEEYQATFTEQHNMLDVRQVYIGKLESKVQDLMCEIRNLLQLESNMVDSFPRQATVNSQEQPKQLLSELKKIAFKVENAEAASSLTASRYIRSESSVHNYSLECRQLFDNLREESLGMLFVYAPQSQRAVFANSLFKTWTGYGVEDFLNAGGDIVISGLPQWETDLRLLDRKERSGKIIIKTKNHGQIPFYYCLTILNKGPLHNHVLGVLYPVRIDAFRG
What are the official names of this protein?
UPF0242 protein CCA_01002.
What is the protein family that this protein belongs to?
Belongs to the UPF0242 family.
Protein: PCKA_SALPK
Sequence: MRVNNLTPQDLKAYGINDVQDIVYNPSYDTLYQEELNPGLEGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTLWWSDKGKGKNDNKPLSQETWQHLKGLVTHQLSGKRLFIVDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELVGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSVMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYHAIRRDALLENVTVREDGTVDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFRLPLFDLAIPTELPGVDTHILDPRNTYASPEQWQEKATALAKLFIENFEKYTDTPAGEALVSAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BUCMH
Sequence: MIHNNRLRIVMQKNWKLSSDSKDLLVRCGIKINLCKQKLIAFSENMPIDVMCVRDDDIPGLIMDGIVDIGIIGENVLEEEVLSRKLRLDSVDYIKLKRLDFGVCRLSLAVPIDKEYTDIYCLNNSRIATSYPHLLKKYFDKKNIIFKSCMLNGSVEVAPRAGLSDAICDLVSTGATLEANGLREVQIIFRSKACLICKTGNISVEKQNVINTLMTRIQGVIKARESKYIMLHAPIKKLEEVIDLLHGAERPTILKLAGDDSRVAMHMVSSETLFWETMEKLKLLGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2006_GEOSM
Sequence: MKIWIDADACPRVVKEIVSRASERLKVPVCLVANTDLSRAHTSLVTSVRVKAGFDVADDYIAENAEACDLVITADIPLAARVVEKGGVALDPRGELYTEENVGERLSYRNLMAELRTDGMLLGGPAQLGLTDRNRFASALDRLLTKMVREHRPQ
What are the official names of this protein?
UPF0178 protein GM21_2006.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: OXLD1_MOUSE
Sequence: MGSPLQTLSRGGRVRAALWCWTQARGLSGRQCPNRVARSLSCSRGFPVRGGRPALGGTMVSVLTESFLQGTQHFSSWDCCQSLHRHRAPVQVTDSRRNLGMDHREEGFQVGTEDDREPKASLPRGNPTGPPCSLPPELEPPTNCCMSGCPNCVWVDYAEALLRLYQDGGEKALAILEEHVTDENLKAFLRMEIRLRMQSGA
What are the official names of this protein?
Oxidoreductase-like domain-containing protein 1.
Protein: SYE1_METCA
Sequence: MSAIKTRFAPSPTGLIHLGNARTALFSALGGDVFVLRIEDTDLERSRAEFVAELMNDLRWLGLDWQEGPRGAEPDPDWYQSRRGEIYATYYRLLEEKGLAYPCFCTPLELEVSRKVQLGSGRPPRYSGRCAHLPADEVRRRHEEGLAATLRFRVPKDRVVEFEDEVRGPQRFAGEDIGDFIIRRADGSPAFFFCNAIDDALMGITRVLRGEDHLANTPRQLMILAALDLPRPRYAHISLIVGDDGAPLSKRNGSRSIKQLREEGYFPEAVVNMLARLGHHYDSAELLGLPALRAGFDIRRLGRSPARFDVSHLDHWQGLAVRGAADDTLWHWLHTETRAVVPDAHRAGFLDLVRSNCLFPKEADAWARILFTDELELAADIAAVAQAAGEAFYLAAIDAATESPDDFAAFLAGLKRRSGAKGKHLFLPLRAALTGSLDGPELAKIYQMLDKPRLHRRLAEFTYESE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP3_YARLI
Sequence: MGKRDRTEDDEVVTKKVKLDKKDKKEKKEKKDKKDKKDKKDKKDKKDKKEKKEKKEKKEKKEEVSDEEEVAEEKPKMTYTASANTIKSSGEYTQCDDLTNVSQSTIDNYFKEHTITIEGEQMRPTMEFSHVTLDPRITKVLTKFPRPTPIQAVSWPYLLAGKDMVGVAETGSGKTFTFAVPALEHVLSTSGGKGVRVLVVSPTRELAMQIYDNIKELCDVVGLHAVCVYGGVPKEQQRSDLKRASFVIATPGRLCDLIDEGSCDLSKVSYLVLDEADRMLEKGFEEDIKKIIGSTRPTGRQTVMFSATWPPEVRKLAEGFMKTPTKVMIGERDELAANKRITQSVEVLDPRAKEGRLLDLLRQYANDDFKILIFALYKKEATRVENTLTRRGYGVAAIHGDLSQQQRTKALDEFKKGEKNILLATDVAARGLDIPNVKLVINLTFPLTVEDYVHRIGRTGRAGKTGQAITLFTEHEKHLSGALINVLRGADQPVPDELLKFGGHTKKKEHGAYGAFFKDVDMTKKAKKITFD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATPD_COXB2
Sequence: MALHLTLARPYAKAAFADGQKANQLEAWLAVFTAFSKIIKNKEVARQIINPKFSDKEIKTLLFDLIQTIEPESTKQLKDKIDHFLQLLIDEKRLMILPDIALVYQQLLNKYQGIIEASVTYVFPLNDEHRQQIQKQLEKRFNAEVKLKMIKDESLLGGVIIRAGNWVMDGSIKGKLTRLAENLKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSCL_DELAS
Sequence: MGMMQEFREFAVKGNVVDLAVGVIIGGAFGKIVDSVVNDLIMPVVGLVFGKLDFSNLFVVLGSVPPGTAMTLDALKKAGVPVFAYGNFITVAVNFIILAFIIFMMVKQINRLRREAPAAPAPAPVTPEDIVLLREIRDSLKR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSX_SALSV
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNANSQLTLLLVGNPDIITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGTSMRVALELVKEGRAEACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAVMGAVLAEEVVGIKNPRVALLNIGEEETKGLDSIREASLMLKTVPTINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFEPLDDGKGVNLRAHR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.