PharMolix/UniProtQA huggingface dataset:
Protein: MNME_EHRRG
Sequence: MSTIFALCTPWGKSGVAVIRVSGQDAVKTFMHFKISNAIKPRVATFTPLYNAAHEVIDEVIVVYFSAPNSFTGEDVVELHTHGSIAVIRMILCELGKIFIPAGPGEFSLRAFLNNKVDLTRAEAIVDLINAETEMQAKQAIRQMSGSLEKLYQSWRQQLIDVLSNMEAYIDFPEEVTSFAVENISFLLDKIKESLENHLNDGRKGEILRQGIYVAILGEPNSGKSTLFNHLAKRDIAIVSEYAGTTRDVLETHIDIAGYPIVIIDTAGIRDSNDPVEQEGIRRAKLKAESADFKIIMLPYEKKDALNNEIIDLIDDRSICVLSKSDSIITQNLININDINFIPVSVCCNLGIEHLLSAIQKKVEADFKFCSTSPFITSDRQRVHIQNAVNILKNISFELPMELISEDLRLSVRELEKVVGVISNEEILDNVFGKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_VEREI
Sequence: MGAVIDDSMPGPGADATGTGPSDARTERETRKLEKRLCRAVGKAIDDFHMIEAGDKVMVCMSGGKDSYTLLDILLKLRARAPIAFDLVAVNLDQKQPGFPAHVLPGYLASAGVPYHIETEDTYGIVKRLIPEGKTTCSLCSRLRRGILYRVASELGCTKIALGHHRDDILQTLLLNMFFGGKMKSMPPKLVSDDGQHVVIRPLAYVAEKDTARWAAQRNFPIIACNLCGSQQNLQRQQVGQMLREWEKKLPGRVENMFNALQNIVPSHLLDARLYDFKNARATGLASADGDKAFDPQELATPAEQVVQIVPTRRSS
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREA_MOUSE
Sequence: MTWELHLLLLLGLGLRSQEALPPPCESQIYCHGELLHQVQMAQLYQDDKQFVDMSLATSPDEVLQKFSELATVHNHSIPKEQLQEFVQSHFQPVGQELQSWTPEDWKDSPQFLQKISDANLRVWAEELHKIWKKLGKKMKAEVLSYPERSSLIYSKHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRIYYLQRSQPPLLTLMMDRYVAHTKDVAFLQENIGTLASELDFWTVNRTVSVVSGGQSYVLNRYYVPYGGPRPESYRKDAELANSVPEGDRETLWAELKAGAESGWDFSSRWLVGGPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTEATKYRNLRAQRLAAMEAVLWDEQKGAWFDYDLEKGKKNLEFYPSNLSPLWAGCFSDPSVADKALKYLEDSKILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKSAMFEKYDISNGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSGTQLASLGPHCLVAALLLSLLLQ
What is the function of this protein?
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: PLSY_SHESA
Sequence: MSQLTLTLLMIVAAYLAGSVSSAVLVCRMRGLPDPRLQGSGNPGATNVLRIGGASSAAMVLFFDMLKGALPTYLAYLMGIDAISLGLIAIAACLGHIYPIFFGFKGGKGVATAFGAMAPIGDDLAICLMASWVVLVLISRYSSLAAIITALLAPLYTWWLDDRFTIPVAMLSTLIIIRHKENIQRLLKGEESKVSRKKRPKAP
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLSA_SHESW
Sequence: MPELALLEEVVEKVRPLLGQGKVANYIPALASVDAGKLGIAVTTVDGETLGAGDYLEPFSIQSISKVFSLTLALTLYEEAEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRQLSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTVDGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSICVWSPELDENGNSLAGTAMLEHLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RL31_PELTS
Sequence: MKKNIHPNYGKARVSCVCGETFETGSTKKELRVEICSKCHPFYTGSQRMIETGGRAERFRKKYGLAK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RBL_SYNP6
Sequence: MPKTQSAAGYKAGVKDYKLTYYTPDYTPKDTDLLAAFRFSPQPGVPADEAGAAIAAESSTGTWTTVWTDLLTDMDRYKGKCYHIEPVQGEENSYFAFIAYPLDLFEEGSVTNILTSIVGNVFGFKAIRSLRLEDIRFPVALVKTFQGPPHGIQVERDLLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKSQAETGEIKGHYLNVTAPTCEEMMKRAEFAKELGMPIIMHDFLTAGFTANTTLAKWCRDNGVLLHIHRAMHAVIDRQRNHGIHFRVLAKCLRLSGGDHLHSGTVVGKLEGDKASTLGFVDLMREDHIEADRSRGVFFTQDWASMPGVLPVASGGIHVWHMPALVEIFGDDSVLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRDLYREGGDILREAGKWSPELAAALDLWKEIKFEFETMDKL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=In the carboxysome RuBisCO is organized into a paracrystalline array (By similarity). This cyanobacterium makes beta-type carboxysomes (Probable).
Protein: MDH_SALDC
Sequence: MKVAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARRPGMDRSDLFNVNAGIVKNLVQQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQHSLDAMLDTLKKDIQLGEDFINK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: T2G3A_AGEOR
Sequence: MKAVIFFCLLSVMVFTVIEAVKEEGTKPAEAARECAAKNKRCADWAGPWCCEGLYCSCRSYPGCMCRPNSG
What is the function of this protein?
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with both the activation and inactivation processes being affected.  The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action).  Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV.  Compared to beta/delta-agatoxin-1 to -3, this toxin appears to affect the insect sodium channel only weakly.
What are the official names of this protein?
U3-agatoxin-Ao1a, U3-AGTX-Ao1a, Beta/delta-agatoxin-7, Mu-2Aga_01.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 01 (aga-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_ACIC5
Sequence: MLVSEFDFHLPEDLIAQEPLADRAASRMLALDRSTGAWQDRMFADLPGFLRPGDLLVLNNTRVIPARLFGRRAGLRTQPGHEATGQVEVMLTEQISEWEWRALVRPGRKVPVGESIHFGNEGLQAEIIAHGEFGERTLRFTPIPDFFHVLERVGHIPLPPYIHREDRPEDRERYQTVYNQQPGSVAAPTAGLHFTPQMLAKLQELGVQTAYITLHVGLGTFQPVRVDKVEDIRLHRERYTLSPETAAAVNAALHENRRVIAVGTTTVRTLEHCATVADGKPLVPHAGETEIFISPGYKFRIVQGLLTNFHLPQSTLLMLVSAFAGREAVLAAYRHAVEQRYRFFSYGDCMFLA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABTB2_RAT
Sequence: MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAPQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQPSSPGPDGVNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSNSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGSSEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQMPSGSSSMAEAAKSRAWTHCRICRAP
What is the function of this protein?
May be involved in the initiation of hepatocyte growth.
What are the official names of this protein?
Ankyrin repeat and BTB/POZ domain-containing protein 2, CCA3, Confluent 3Y1 cell-associated protein.
Protein: AL10_ANELE
Sequence: MDLTSMAMQETTAAAEEDRLPCSEVPVKEKTKKITWVRKWNSTDVFHILFIGGLHVLCLFAPSTFSWKSFWVCFALYAICGVFGTTLSFHRNLTHRSFKLPKYLEYFFAYVGLHALQGDPVWWVSTHRYHHKYTDTYLDPHSPIEGFWFCHIFWLFDSKYIIEKCGRYENAGDLMKQSYYRFLERTFVYHVYLQAALLYLFGGFPFIVWGMAVRTILGFHLSWLVNSVCHRWGNRPWNTGDLSTNNWFIAMLTSGEGWHNNHHAFEYSARHGIEWWQIDTTWYIIKLLEYLGLATDIKVPSEIHKRKMSFKN
What is the function of this protein?
Catalyzes the desaturation of 20:2Delta(11,14) and 20:3Delta(11,14,17) to generate sciadonic acid (20:3Delta(5,11,14)) and juniperonic acid (20:4Delta(5,11,14,17)).
What are the official names of this protein?
Acyl-CoA C20 Delta5-desaturase, Acyl-CoA 5-desaturase (non-methylene-interrupted), Acyl-CoA 5-desaturase AL10.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS16_HELHP
Sequence: MATVIRLTKMGRKKKPFYRIVVTDSRKKRDGGWIESLGYYNPLVEPALVKYDAQRLEYWKNVGAKMSERVAKLTSKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HSLV_ERWT9
Sequence: MTTIVSVRRNGQVVIGGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADENASLIITGNGDVIQPENDLIAIGSGGPYAQAAARALLENTDIGARDIVEKALGIAGDICIYTNHNLTIEELSSKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ECO7I
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CID2_SCHPO
Sequence: MNEEKRGLCMNIRYLKNVLRKARKIDDTIQLSLNSAKWEYPEGKVHETQEERCQNVKKKLFEGWLSRDQFLKECQTIVRSQLDQDRNTSKSPLKSQQQLPSSSTTQVSERLDPYAKEVQVQLSPPEEVQIVLQSELSVEQIIRDQTWEVLTNACPGMFKDWRDTYKD
What are the official names of this protein?
Protein MIX23, Caffeine-induced death protein 2.
What is the protein family that this protein belongs to?
Belongs to the MIX23 family.
Protein: GSM1_PICGU
Sequence: MTKKLSPLEKQARRPASRACSFCHSKHLQCSNNRPCKNCVKRNIADQCRDVERKRANYMTLAAKNKQGSPNTVSLESSSSPFSPLHKGHINSQSSQPLDPSSGRVNTDFFSQSETTVPSPWPMDLESKERTNAILNTTDDVLNKILYDEQASKVPSAQASEMTPSNSSIDGVFNSNYLNQEYLMLGDIILNSKPASPTPSSTSEYQTIPPNEMMGTVDYNEVYRDTKSKKLKESRPFISLGFSNPPDLDNRKLPGEINIANEIMDPSKRAQVTTTNDYVSPLVTRHIYQSVQDIYANKIINYEYPTSYHALTFFLKKRFSGTSLPPEQKQQKRNNLLIILKLIASYRPTFISAHKSLLKPYDLMFLEMTFQRSLIDYEKLSHLNSSPTIIWRRTGEIVSISDEILSLLGYSLNSILSKRTFIMELMYDDESIINYFKLFKSVAVGNLHSSIITRCKLMKNPDRDRSTRASTTGTEQQLTEADYIEFCAVWTVKRDLFDLPMLIMGQFLPVLPAGDGVRRY
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.
What are the official names of this protein?
Glucose starvation modulator protein 1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1978_KLEP3
Sequence: MSEQPFWQQKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRNYERRFEYEPDCIKLTRENLPTFEWLPPTCAYRLLAEGKSLPAWHPLLTGSKAAMHGERISVRHIAVPESTVVDWQDHILNLPDRAR
What are the official names of this protein?
UPF0260 protein KPK_1978.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: PHF24_PONAB
Sequence: MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSIRRTGELPGSRRGTVEGSVQEVQEEKEAEAGTSVVQEESSAGRAAWERLRDGRGVEPEEFDRTGRFTPPAFIRPTRKLDDDKPPEICLEPREPVVNDEMCDVCEVWTAESLFPCRVCTRVFHDGCLRRMGYIQGDSAAEVMEMAHTETGWSCHYCDNINLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFLRYRHQAAKRGDRDRALSEEQEEQAARQFAALDPEHRGYIEWSDFLSHESLLLLQQLRPQNSLLRLLTVKERERARATFLARGSGSTISEAECRRAQHSWFCKRFPEAPSCSVSISHVGPIADSSPASSSSKSQDKTLLPTEQESRFVDWPTFLQENVLYILAARPNSAAIHLKPPG
What are the official names of this protein?
PHD finger protein 24.
Protein: IF4G1_ORYSJ
Sequence: MEKDHQPVISLRPGGGGGGPRPGRLFSPAFAAAASGSGDLLRSHVGGASKIGDPNFEVRERVRYTRDQLLELREIVDIPEAILRINQEIDIELHGEDQIWGRPESDVQVQTQTQAQPHNRYGETDNRDWRARTVQPPAANEEKSWDNIREAKAAHASSGRQQEQVNRQDQLNHQFASKAQVGPTPALIKAEVPWSARRGNLSEKDRVLKTVKGILNKLTPEKFDLLKGQLMESGITTADILKDVISLIFEKAVFEPTFCPMYAQLCSDLNEKLPSFPSEEPGGKEITFKRVLLNNCQEAFEGAESLRAEIAKLTGPDQEMERRDKERIVKLRTLGNIRLIGELLKQKMVPEKIVHHIVQELLGSGPDKKACPEEENVEAICQFFNTIGKQLDENPKSRRINDTYFIQMKELTTNLQLAPRLRFMVRDVVDLRSNNWVPRREEIKAKTISEIHDEAMKTLGLRPGATGLTRNGRNAPGGPLSPGGFPMNRPGTGGMMPGMPGTPGMPGSRKMPGMPGLDNDNWEVPRSKSMPRGDSLRNQGPLLNKPSSINKPSSINSRLLPHGSGALIGKSALLGSGGPPSRPSSLMASLTHTPAQTAPSPKPVSAAPAVVPVTDKAAGSSHEMPAAVQKKTVSLLEEYFGIRILDEAQQCIEELQCPEYYSEIVKEAINLALDKGPNFIDPLVRLLEHLHAKKIFKTEDLKTGCLLYAALLEDIGIDLPLAPALFGEVVARLSLSCGLSFEVVEEILKAVEDTYFRKGIFDAVMKTMGGNSSGQAILSSHAVVIDACNKLLK
What is the function of this protein?
Plays a role in the accumulation of a sobemovirus (RYMV) during viral infection.
What are the official names of this protein?
Eukaryotic translation initiation factor isoform 4G-1, eIF(iso)-4G-1, eIF(iso)4G-1, Eukaryotic initiation factor iso-4F subunit p82, eIF-(iso)4F p82 subunit.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: RA212_ARATH
Sequence: MCGGAIISDFIPPPRSRRVTSEFIWPDLKKNLKGSKKSSKNRSNFFDFDAEFEADFQGFKDDSSIDCDDDFDVGDVFADVKPFVFTSTPKPAVSAAAEGSVFGKKVTGLDGDAEKSANRKRKNQYRGIRQRPWGKWAAEIRDPREGARIWLGTFKTAEEAARAYDAAARRIRGSKAKVNFPEENMKANSQKRSVKANLQKPVAKPNPNPSPALVQNSNISFENMCFMEEKHQVSNNNNNQFGMTNSVDAGCNGYQYFSSDQGSNSFDCSEFGWSDQAPITPDISSAVINNNNSALFFEEANPAKKLKSMDFETPYNNTEWDASLDFLNEDAVTTQDNGANPMDLWSIDEIHSMIGGVF
What is the function of this protein?
Transcription factor involved in the activation of hypoxic gene expression and in ethylene response.  Partially redundant with RAP2-2.  Acts as a downstream regulator in the ethylene signaling pathway.
What are the official names of this protein?
Ethylene-responsive transcription factor RAP2-12, Protein RELATED TO APETALA2 12.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=Localizes to the plasma membrane under aerobic conditions, but accumulates in the nucleus upon hypoxia.
Protein: LEXA_BACP2
Sequence: MTKLSKRQLDILTFIKEEVKSKGYPPSVREIGEAVGLASSSTVHGHLARLETKGLIRRDPTKPRAIEVLDEEELNIPKSAVMNVPVIGKVTAGLPITAVENVEEYFPLPETFAAPDEQVFMLEIMGESMIDAGILDKDYVIVRQQSTANNGDIVVAMTEEDEATVKRFYKEDTHFRLQPENPSMEPIILQNVSILGKVIGVFRNIH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL14_PAEAT
Sequence: MIQQESRLKVADNTGAKEILTIRVLGGSGRRYAGIGDVIVATVKDAIPGGNVKKGDVVKAVIVRTKKERRRADGSYIKFDENAAVILKNDGDPRGTRIFGPVGRELRDKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GCP4_DROME
Sequence: MIHDLLLACRSHNPEQLGIKAFNETTVIDQFIHPCEREIFMDIIKIIKVYQEVEQFTHSSGRKSDTHGELPDSLHGYYLLNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNALYAKFPLLVFMRNLITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAFFSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPEDYIWQYEVNMSQLPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDIYQLWSGRESEFFKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLLGRGEFYLEFCSQMVGTMETYREERFKNVTRSFELAATVTGITDDLDKFSLICQRSTSEPDDTSDFNFLQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTYQYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQFGILMNVIKSRSDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQTKDPSDDLEDEVDQLNESFGVQIASLIQLLVDVKSASCLGPLSQLLLRLDFNCWFSASHNTSA
What is the function of this protein?
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
What are the official names of this protein?
Gamma-tubulin complex component 4 homolog, Gamma-ring complex protein 75 kDa, d75p, dGrip75.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: OPSD_CARAU
Sequence: MNGTEGDMFYVPMSNATGIVRSPYDYPQYYLVAPWAYACLAAYMFFLIITGFPVNFLTLYVTIEHKKLRTPLNYILLNLAISDLFMVFGGFTTTMYTSLHGYFVFGRVGCNPEGFFATLGGEMGLWSLVVLAFERWMVVCKPVSNFRFGENHAIMGVVFTWFMACTCAVPPLVGWSRYIPEGMQCSCGVDYYTRPQAYNNESFVIYMFIVHFIIPLIVIFFCYGRLVCTVKEAAAQHEESETTQRAEREVTRMVVIMVIGFLICWIPYASVAWYIFTHQGSEFGPVFMTLPAFFAKTAAVYNPCIYICMNKQFRHCMITTLCCGKNPFEEEEGASTTASKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (PubMed:18422881).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: MIAB_CLOPS
Sequence: MTLENNMDKKLFCISTYGCQMNEEDSEKLSGMLKSQGYERTENKEEASIIIFNTCCVRENAENKVFGNLGQLKQLKKKNPNLVIAICGCMMQQVGMADKVLKTFPYVDIIFGTHNAHKFPEYLHRVLQEGVQVKEILNKEEGIVEGLPIDRKSDVKAFVTIMYGCNNFCTYCIVPYVRGRERSRKSEDIIKEIEELVSKGYKEITLLGQNVNSYGKGLEEDIDFAGLLRKVNEVKGLERVRFMTSHPKDLSDDVIMAIKECDKLCEQVHLPVQSGSSRILKEMNRHYDREYYLDLVKKIKSEIPDVTLTTDIIIGFPGETEEDFLDTLSLCEEVGYDSAFTFIYSRRNHTPADKMENQIPDDIKHDRFNRLVEAINKKVVIKNKEYEGKVVEVLVEGPSKNDETKLTGRTRNGKLVNFAGDEKLVGELVNLKIVRAQPFSLIGEIVE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_SACEN
Sequence: MARQPLIAGNWKMNLNHLEAIALVQKIAFSLPEKYFAKVEVAVIPPFTDIRSVQTLIDGDKLLLKHGAQDVSEHESGAYTGEVSGPMLAKLGCSYVVVGHSERREHHAETDEVVNRKVRAVLKHGMSPILCVGEPLEVREAGGHVEHSTTQLINALKGLKTEQIRQVVVAYEPVWAIGTGKVATAADAQEVCAALRTALADKYGKEIADEVRVLYGGSVKSSNIGELIGQNDVDGALVGGASLNGDEFTKLSAMAAGGPLP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INH14_ECOLI
Sequence: MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
What is the function of this protein?
Involved in the transposition of the insertion sequence IS5.
What are the official names of this protein?
Transposase InsH for insertion sequence element IS5-14.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: Y2716_MYCTU
Sequence: MAIEVSVLRVFTDSDGNFGNPLGVINASKVEHRDRQQLAAQSGYSETIFVDLPSPGSTTAHATIHTPRTEIPFAGHPTVGASWWLRERGTPINTLQVPAGIVQVSYHGDLTAISARSEWAPEFAIHDLDSLDALAAADPADFPDDIAHYLWTWTDRSAGSLRARMFAANLGVTEDEATGAAAIRITDYLSRDLTITQGKGSLIHTTWSPEGWVRVAGRVVSDGVAQLD
What are the official names of this protein?
Uncharacterized protein Rv2716.
Protein: CLPX_CHLT3
Sequence: MAKGKQSGSSNSRDELMVNCSFCGRSSDEVNSMIAGPNAFICDRCIQSAVDIIKHDLSAITTKRRSNKTAKLVKPTEIRDELNKYVVGQERAKKALAVAVYNHYKRIESQEWLLEEDDVVIEKSNILLIGPTGTGKTLLAQTLANILDVPFTIVDATSLTEAGYVGDDVESILARLLQAADYNLERAEKGIIYIDEIDKIARKSANVSITRDVSGEGVQQALLKILEGTVAGVPPKGGRKHPEQHLINVNTKNILFICGGAFEGLEKVISRRLAQNAMGFGTAITAASEKESIELISKVTPEDLYQFGLIPEFIGRMPFIATLDPLNKEALKNILIEPKNAITKQYKKLFEMENVELIFDTDALDLVVDTAVKRGTGARALRSVLEEVMLNIMFDLPNMNEVKTCIITKECIEKKAEPMYLYGESERKKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.