PharMolix/UniProtQA huggingface dataset:
Protein: PROF_SUBDO
Sequence: MSWDSYLDNLVAQSKDASGTAHVDRCCIIGLDGGAAWTTAGHACALKLQGQEGPNIAKCFKSKDFTAFMSGGVRAEGEKYQFLREEEGKTVLAKKKGNGAITLQASKTAIVLGHCPEGGQQGNTNKAVGVIADYLESLGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
Protein: YCP2_YEAST
Sequence: MLYLLKKLKHIDSYGESNLSMFYLKFYCPWKLCPLLPILYGRNKSVQNAWSCHKLHRFIDFPTPSANMNFFFFIRVCYGTVSLFISTFLKKISFFIYVNFTVYF
What are the official names of this protein?
Uncharacterized protein YCR001W.
Protein: LCN3_LACLL
Sequence: MKIVLQNNEQDCLLACYSMILGYFGRDVAIHELYSGEMIPPDGLSVSYLKNINMKHQVSMHVYKTDKKNSPNKIFYPKMLPVIIQWNDNHFVVVTKIYRKNVTLIDPAIGKVKYNYNDFMKKFSGYIITLSPNSSFTKKKRISEIIFPLKKIFKNRNTFLYIFSLFISQIVALWFSIILRDILNKSHDITYSFIMMISLVLFQTLSLLMKLGAQKNTNLLYESKISRQIFKGIFSRPLLYFRNNSVGTIIEKINLRTGIRDGILLKIFPSLLNFFTVFIVIIYLGTISFTLTLFLVIMNLLYMIFSFSLISIKRQANIQYTQQTIDFTSVVQEDLNQIEQIKAQANEKECVKRWTKKSAQTIFSYNKILNIDGITSAFNQGFNYICVILMMIFGIYLNQGNLVSIPDLIIFQSGISLFVSAVNQIQDVMFEISRLSIYGNKISDLLIENPQRIDNIEKHSNNAIILKDISYSYELNNYIFNNINFSIKKGEKIAIVGKSGSGKSTLFNILLGLISYEGEVTYGYENLRQIIGVVSQNMNLRKGSLIENIVSNNNSEELDIQKINDVLKDVNMLELVDSLPQKIFSQLFENGKNLSGGQIQRLLIAKSLLNNNKFIFWDEPFSSLDNQNRIHIYKNVLENPDYKSQTIIMISHHLDVLKYVDRVIYIDDKKIMIDKHNNLLLNDSYNSFVNE
What is the function of this protein?
Probably implicated in the export process of the lantibiotic lacticin-481/lactococcin-DR.
What are the official names of this protein?
Lacticin-481/lactococcin-DR transport/processing ATP-binding protein lcnDR3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1050_YERP3
Sequence: MPKRTYAMRYVAGQPVEQIFPGAAKQLDKGLPLGEPLPTAELLRVVVWNIFKQQRAGWLPVLKELGRDTQLMLLQEAQTTPELVRFATASYQAADQVPAFSLPQHPSGVMTLAAAHPVYCCPLREREPLLRLSKSALVTVYPIHDGRLLMVVNIHAVNFSLGVDVYSKQLDPIGDQIASHRGPVILAGDFNAWSRQRINALQHFAQDAGLQEVEFRVDHRSRAFGRPLDFIFYRGLTVIDASVLVTRASDHNPLIVEFQP
What are the official names of this protein?
UPF0294 protein YpsIP31758_1050.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV58
Sequence: MRGNNPTLREYILDLHPEPTDLFCYEQLCDSSDEDEIGLDGPDGQAQPATANYYIVTCCYTCGTTVRLCINSTTTDVRTLQQLLMGTCTIVCPSCAQQ
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: DSBD2_PSEAE
Sequence: MRVLILLLMLLLPGLSQAQPGDDLFAPRGATQTDFLPVEKAFRFTWERLDDGQVQLRWQIAPGYYLYQKRLRFDGLDPALQPQLPPGESHSDEFFGESQVYRQSLELTLPAAAAGQLRLGWQGCADAGLCYPPQSQALDLGGTGPAAAGTSGEVAEDQGLAGSLQAGNLAWSLLLFFGLGLLLAFAPCSLPMLPILAGLVVGSGAGPRRGLLLAGSYVLSMALVYAGLGVVAALLGGNLQAWLQQPWLLGSFAALFVFLALPMFGFFELQLPAALRDRLDGLSRGRKGGSLAGAAALGALSGLLVGPCMTAPLAGALLYIAQTGNALHGGLVLFSLGLGIGMPLLLLVTVGSRFLPKPGPWMNLVKGVFGFLFLGTAWILLRPLLGEALWIGLGGALLLVLAYAALHTARGLARHAVLFGAAGCIFGLWGAAMLLGAAAGADDPWRPLQVYAAANRGATPTASAHEAFLTVSQPAELDRQLAAAKAEGQWVLLDYYADWCVSCRIMEKQVFAKPDVLAALQGVRLLRLDVTADNAASRELLHRYQVPGPPSLIWIGPEGEERRARRLTGEVDAGGFLAHWQATRERG
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD 2, Protein-disulfide reductase 2, Disulfide reductase 2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DABA2_RHOBA
Sequence: MSSGNTSSQNHSPVNNQPTRLKSPLPALHKDTQPNTSHQATNVLQAIEHARHFLPAQGPISVFVHHNTLHAFEDLPFEKAVIEGGRRFGCEPYLSEERYHQELLRGRISREDLREVLMADLQDDADKLVATFGTRYTLRLSMLQTELQPMPESGLSWVLAESELLKRFREEVPAPYREKTITQTRGWVMRHLEPITTDTTSSNPASPLPAPLQDRLKAAGESQIHRWNDQQWESFTLHALWETCQQGVEKAEVQTPNTASNDSLHRLMRGELGIDLKTKIDDVLIRFCGCFLDQGFADWKLPERENGFAKAFADLYLGRWAIRADWMKHVDASLREVQSPDWDAIQSIEQSLERMGISNNECEGFLSECLLSLRGWAGMIWQMETNGPFLANPIPEGSLNEYLAIRLILLAHAIEHFGKAKFNVGTASEILRLALKSADVRSASSVRSRTHTVFQLAQLGGWTPEQMLNMSSAQWRCLITEIESFASLDRRRLLHAAYERHYANQALDAISIHSRRRRELATNSRRRPAYAAIFCIDDREESFRRHLEEVAPDCRTASAAGFFAVAMYYQGADHASFRPLCPAIVKPQHYVREEPLFSSMAAGERRAVRRRRLGWFAHQVHQNSRTLIGGWVTGLFGAIATVPMVARILAPRLTSQIRESMGSLVRPPATELHLERLADAPGSDPASMGYSLDEMSQIVVRILQDIGMVDAFPPIIVFFGHGSGSLNNPHESAYNCGACSGGRGGPNARAFAVMANDPRVRRRVAEQGIELPDEVRFVGAYHNTCNDDVDYYDLDLLPRSLRELFRRIESDVIETRARNAHERARRFESAPLDLTPQEALEHVEERAEDLSQARPEYNHATNALVTVGRRDWSRGLFMDRRAFVTEYDPTVDDENGHILTRILQAAIPVCGGISLEYYFSTVDVEGYGCGSKLPHNVASMVGVMTGAASDLRPGLSQQMVEIHEPMRILFVIETTPEMLKKIISENEGIRRMVEGNWVQLAILDPSTYTIQRYIDGHFEPHVVTDREIPTVQSSMHWYRGQRDHLGFATIQESEIKTPVSSSESDANTSEVLV
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA 2.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHYDA_ECOL5
Sequence: MRVLIKNGIVVNADGQAKQDLLIESGIVRQLGTDISPQLPCEEIDASGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: PDXH_MYCSK
Sequence: MKKADNEHLARMRVEYGSVEKDGSADLDVDWLADGWVALLRRWLADAEAAGIAEPNAIVLGTVDAGGRPVTRTVLCKSVDDTGITFFTNYGSAKGEDLASTPYASATFPWFALGRQVHVRGPVTKVSAEETADYWSKRPRGSQLGAWASQQSRPIASRAELLDQLAEVTERFADHDTVPVPPDWGGYRITAEVVEFWQGRESRVHNRIRVHDGRIERLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: DDL_SHESW
Sequence: MSRINLLLLCGGGSAEHDISLMSANYFESSLAKSDQFSVLRVELDKLGQYRTAAGDECELTNNREIRFRDETKAPWPVDYVIPCIHGYPGETGDIQSYFNLIQLPYFGCESEASSNCFNKITAKMWFSALGIPNTPYIFLHQYDDEAISQAQTALANWGSIFIKAASQGSSVGCYKVDDSSKVAQVLKDAFGYAPYVVVEKTIKARELEVAVYEYNGEIVATLPGEIICDTNTFYTFDEKYAKSSKARTDVVAKDVSVELSEQIRAYAIKAFKGMKLRHLSRIDFFLTAENEILLNEINTFPGSTPISMFPKMLQNHGHDFTEYLSLVINNQLSAKD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPX_COREF
Sequence: MATTHFDGTDTPTSGELPAVGDTLPDFTVVDTNLGEVSLSDLKGKKLVLNIFPSVDTGLCAESVRRFNAEAAGLDNTTVLCVSKDLPFALGRFCGAEGLDNVTAASAFRSTFGEDYGVVLEGSPLKGLLARSVIVADEDGKVIYTQLVDEIKTEPDYASAIKALG
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: HCAD_SHISS
Sequence: MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIAIGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKVELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLIDENIALKSL
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: YDH3_PLAFS
Sequence: PQYQFVGAKLFRWWCWRRRGWRRRWWLVIKLMLIETSFALDCEALCFSGVRQV
What are the official names of this protein?
Uncharacterized protein 3' to Asp-rich and His-rich proteins.
Protein: DCTA_KLEP7
Sequence: MKTSIFKSLYVQVLTAIAIGILLGHFYPELGAQMKPFGDAFVKLIKMVIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEVVSTIALIIGLIIVNVVQPGAGMNVDPSTLDAKAVAVYAEQAKDQGVVAFLLDVIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVVVLGSIARATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDAKQMDDVLNNRVPANKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIVB4_BRUSU
Sequence: MSLKVFLQAGVACAALSLAGAAGASAEPLKIALVETLSGPQASTGLLYRAAVLYQLGKINEAGGFNGEKIQILEYDNQGGPVGAADRVKAAIADGAQIIVQGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGAEALELTGSKCHFYHFRFSPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTVVANAKEIGYEVVDKTLHEVNKIQDFSPYVAKIQAANVDTVFTGNWSNDLLLLMKAASGAGLKAKFATSFLDQPGNIGNAGAIAEGHIVSTPFNPEANGEASMAFAEDYKKVTGHYPSYVEPAAVFGLQLFGEALKNVKPGEGKINTTDIALAIENASVKTPMGDYSMRSDDHQAKFPMVVQEVSKKARIKADGTEYGFLPFKTFTGDESIDPVQESCSMKRPG
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 4.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: CANB_KLULA
Sequence: MGAAPSRIVDNLLDDTNFDRAEIERLKKRFMKLDKDSSGSIDKTEFMSIPGVSANPLAKRIIEVFDEDNSGDVDFQEFITSLSIFSGRGETDAKLRFAFRIYDIDKDGYISNGELFIVLKIMVGTNLEDEQLQQIVDRTIMENDVDGDGKLSFEEFKKAAETTEVIQSLTLQHNI
What is the function of this protein?
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase.  Confers calcium sensitivity (By similarity).
What are the official names of this protein?
Calcineurin subunit B, Calcineurin regulatory subunit, Protein phosphatase 2B regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: RL24_METTP
Sequence: MVSKQPRKQRKARFNAPLHMRQRFMHAMLSPELRKEYKKRSAQVKKGDTVKVMRGDNAGVEGEVLSVDLKRCVITVAGVSNFRADGTEVPRPIHPSNVMITKLDLDDDEREKIFSR
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RX_RAT
Sequence: MHLPGCPPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKEDGILDTFPAERSSRGSKERDPRLGARSACPKAPAGGSESSPPAAPGLVPEFEATRPCYPKEQGEARPSPGLPVGPAAGDSKLSEEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSSALAPLGGPGSGSGPPGSALPLEPWLGPPLPGGGATALQSLPGFGPPGQGLPASYTPPPPFLNSAPLGPGLQQLGPPPAYPCAPAFGDKFSLEEAYPRNSSIAALRLKAKEHIQAIGKPWQAL
What is the function of this protein?
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.  Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter (By similarity).
What are the official names of this protein?
Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMI_FLAPJ
Sequence: MNKKVILMILDGWGKSPDPKVSAIDNANIPFINSLYKNYPSAQLRTDGLNVGLPEGQMGNSEVGHMNLGAGRIVYQDLAKINLAVQNKTLSQEKALKEAFQYAKENNKPIHFLGLLSDGGVHSHTSHLRGLLDAAQNFGLKKTFIHAFTDGRDVDPKSAIATIENLNKYIHNTPAKLASVIGRYYAMDRDKRWERIKLAYDLLVNGKGKPSQDAVLSISNSYQNNITDEFIEPIIMTDDNNNPIATIQEDDVVIFFNFRTDRGRELTEALSQQDFHEQNMHKLNLYYVTLTNYDETYKNVKVIYNKDNITQTLGEVLEKAGKKQIRIAETEKYPHVTFFFSGGREQPFLGESRILKNSPKVATYDLQPEMSAYELTEALIPEIEKTEADFICLNFANGDMVGHTGIMSAAIKACQAVNKCVEKVITAALAHNYTTIVIADHGNCETMINPDGTPNTAHTTNPVPIILVDKELKTIHDGVLGDIAPTILDLMGIKKPEVMTRNSLL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: NCAP_MABVM
Sequence: MDLHSLLELGTKPTAPHVRNKKVILFDTNHQVSICNQIIDAINSGIDLGDLLEGGLLTLCVEHYYNSDKDKFNTSPVAKYLRDAGYEFDVIKNADATRFLDVSPNEPHYSPLILALKTLESTESQRGRIGLFLSFCSLFLPKLVVGDRASIEKALRQVTVHQEQGIVTYPNHWLTTGHMKVIFGILRSSFILKFVLIHQGVNLVTGHDAYDSIISNSVGQTRFSGLLIVKTVLEFILQKTDSGVTLHPLVRTSKVKNEVASFKQALSNLARHGEYAPFARVLNLSGINNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAAHDAEVKLQRRHEHQEIQAIAEDDEERKILEQFHLQKTEITHSQTLAVLSQKREKLARLAAEIENNIVEDQGFKQSQNRVSQSFLNDPTPVEVTVQARPMNRPTALPPPVDDKIEHESTEDSSSSSSFVDLNDPFALLNEDEDTLDDSVMIPGTTSREFQGIPEPPRQSQDLNNSQGKQEDESTNRIKKQFLRYQELPPVQEDDESEYTTDSQESIDQPGSDNEQGVDLPPPPLYAQEKRQDPIQHPAANPQDPFGSIGDVNGDILEPIRSPSSPSAPQEDTRMREAYELSPDFTNDEDNQQNWPQRVVTKKGRTFLYPNDLLQTNPPESLITALVEEYQNPVSAKELQADWPDMSFDERRHVAMNL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication.  During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the filoviruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RS12_CLOBM
Sequence: MPTISQLVRKGRKTIASASDSPALKECPQKRGVCTVVKTTTPKKPNSALRKVARIRLTNGYEVTAYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDAAGVANRMQSRSKYGAKKPKQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IHFB_YERPP
Sequence: MTKSELIERLAGQQSHVPAKVVEDAVKEMLEHMAGTLAEGERIEIRGFGSFSLHYRAPRVGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MEP6_COCP7
Sequence: MRLSSSLIALVALAGQALALPFNELAERDTGLDVKLIPIGNTRVKAIITNNADHEMSFVKYNTLFDSSPVRKVQISKDGSIIPFKGIHLYYDIDNLPKEAYKTLAPGASAEAEFDIAETSDLSAGGSFKISAEGSIPVIDGQGTKPTSSIRFKANTLTMDIDGEMASRVASAIPELNKRTRVDNQTCTGQYAQLLQGGLRTCATYAQRAAQAASGGNAQKFQEYFKTTNQQTRQNVARRFQAIAQECSSANQGRTIYFCQDVYGYCQGAIAYTVPDRSHVVNCPAYWSLPPVLNRGLGPDHGYVIVHEFTHAPSVFSPGTVDHAYGYEQCRRLNAQQSLNNADSYSLFAADVSRN
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine.  May be involved in virulence (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog MEP6, Deuterolysin MEP6, Metalloproteinase 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_RICCO
Sequence: MALYRTARRPLQMMLFSRLGNPEQNYSSWARKDASQSAFGMFVRLFSAHAPAAAEQMSLIKQLRERTSAPIKDVKASLVDCNWDIEAAQKDLRKRGKVLASKKSGRAATEGLLALAQNEGKAALIELNCETDFVARNDIFQCLALSLAKQALLTENTAQQASGIHPVGPECLEDLMINLEHPKISGETTVQNAITEVAAMMGENVKLRRGFVMSTSLPGVLSTYLHTSPQPGLGRIAGLLSLEIEDGNSQLDVLHHVGSELAMHVVAAKPLFLTKELVSSDALESEREILKSQAESTGKSQMAIEKMVEGRLRKYYEEVVLMEQKFIINDAVNVKTVLNNLSKEVGSPVKIGSFFRMEVGEGIQRLEATSADEPVAQAA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SOTB_SHIB3
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMLIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ABP2_SCHPO
Sequence: MNFYSLLPSRHDVSADNITEKFCQFCLCCNPWYAGADTRQLANAFNMIPKSEGQKFEIWVLFLLVRQYHQKIINSWSKLVGFLGVERKDEQSTQKIQQYVVRLKRWMSQTHVDAFFDYLLNKPNPYYLEIPETQPQVRCNVNVTDDLVIKSLRAGLMSHPDVNSSSISTMRTSTSPSNWIHSASASLDDNTHNLGSFVTNPHADSQECPTPQSLLMRASHHMSERGSQQAHQTTPQNHSLPHPPNMFEPPDEDHQLPSAANNSHNHDHAFQTAEAVGVADSIDPDWHQWPDDLRDVSSPKESDGLNDSWSRQTNQVETENVENEAGVPRKRGRPPGARNKIKRLRSEPSVSLTLSISWYERFEKLMHAQNTMLRSAFSHVARLPMETVSQLLSHYTETISQYLPPSETSPIPKTPNFKFISSTLLALVSSHSEILEASTDRLIWTVHQGPLTATICHAFNLEKAPSMHSLAEAQMIPDVPISHSNSMEPLDTVSSLKLEIAKLNAALKEKNLELENLKRKIMNAVFD
What is the function of this protein?
Binds, preferentially, to the Maundrell ARS consensus sequence within ARS3002.
What are the official names of this protein?
ARS-binding protein 2.
Protein: NDK_THEVO
Sequence: MDRTLVLLKPDAVKRRLVGKIIERFEEKGLKIVAMKFMQMTKDQAKTHYSVHQNKPFFNDLVNYITSGPIVAMILEGAHAIEIVRLMSGATDGSKAQPGTIRGDYSMGIEKNIIHASDSLEAYNHEMPIFFSDNEIIEWAYGDEVIY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_SYNJB
Sequence: MIHPEEVERLRGVNVYLIGMMGSGKSTVGSELAAQLRFQFFDTDGLVEQVGGSSIAQIFAEHGEAYFRDLETQVLAQLSSYTRLVIATGGGIVLRPKNWSYLHHGLTVWLDVAPELIWQRLKRDPGQRPLLQTPDPQAALYKLMQEREPFYAQADVRVPIRSETSPPQLVEQIWQAIRARLRDGIPS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_ACIBS
Sequence: MKVQQYRLDELAHLVKGELIGEGSLQFSNLASLENAEVNHLTFVNGEKHLDQAKVSRAGAYIVTAALKEHLPEKDNFIIVDNPYLAFAILTHVFDKKISSTGIESTARIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSYVTITGSSKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQIAHNVHIGSNTAIAAKCGIAGSTKIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISEAGTYSSGTGLFENNHWKKTIVRLRQLADVPLTQITKRLDHIQAQIESLESTFNLRK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.