PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_PSEF5
Sequence: MSDLSHIRNFSIIAHIDHGKSTLADRFIQMCGGLAEREMEAQVLDSMDLERERGITIKAHSVTLYYKARDGITYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKIDLPQADPERVKEEIEKIIGIDATDAVTCSAKTGLGVDEVLERLVTTIPAPTGNIEDPLQALIIDSWFDNYLGVVSLVRVRHGRVKKGDKILVKSTGKIHLVDSVGVFNPKHTATTDLKAGEVGFIIAGIKDIHGAPVGDTLTLSSTPDVEVLPGFKRIQPQVYAGLFPVSSDDFEDFREALQKLTLNDSSLQYTPESSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVIFELQLKNGETIYVDNPSKLPDLSAIEDMREPIVRANILVPQEHLGNVITLCIEKRGVQHDMLFLGSQVQVTYDLPMNEVVLDFFDRLKSTSRGYASLDYHFDRYQSANLVKLDVLINGEKVDALALIVHRDNAHYKGRALTEKMKELIPRQMFDVAIQAAIGGQIVARTTVKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKQVGNVEIPQEAFLAVLRLDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y5437_BACAC
Sequence: MTENNDIKMVIITGMSGAGKTVALQSFEDLGYFCVDNLPPMLLPKFIELMADSKGKMNKVALGVDLRGREFFEHLWGALDDLSERTWIIPHILFLDAKDSTLVTRYKETRRSHPLAPTGLPLKGIEIERSLLTDMKARANIVLDTSDLKPKELREKIVHLFSTETEQAFRVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIPHMKPLTGLDEEVSSYVLKFNETHKFLEKLTDLITFMLPHYKREGKSQLVIAIGCTGGQHRSVTLTEYLGKHLKPEYSVHVSHRDVEKRKGH
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BAMEG_5437.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: HSLV_AMOA5
Sequence: MLKIKSTTVIAVMHNNEVAIGADGQATMGSTVVKGNVNKIRKLLDGKVLTGFAGSTADAFTLLDRFDEKLQRYFGHMKRSAIELAKDWRTDRYLRRLEAMLIAVNKEELLLISGTGDVIEPDNGIVTIGSGSLYAESAAIALKKHAPHLTAEEIVRESLTIAADICIYTNDNLTIEKIS
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_RICAE
Sequence: MSDNLSLHGTTILCLKKNEEIIIAADGQVSHGNTVLKSTARKLRTIANNKIIAGFAGSTADGLALFEKLAVKIEQHKHNLLRSAVELAKDWRSDKYLRRLEAMMIVADRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSYENNLTAEEIALKSMNIAADLCVFSNHNIIMEKVV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEU2_STRCA
Sequence: ALADAALRQCMPCGPGDRGNCFGPSICCGAELGCYVGTAETLRCAEENYLPSPCRAGGQPCGAGGRCAAPGICCSDETCSLEPACLEEAGERGGEPAQKNLTGLDASAGDFLLKLMHLAANRQQQGGKGPLL
What is the function of this protein?
Neurophysin 2 specifically binds vasopressin.
What are the official names of this protein?
Neurophysin 2, MSEL-neurophysin.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHMA_ECO45
Sequence: MNALLTNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASHPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRVKGSY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.
What are the official names of this protein?
2-keto-3-deoxy-L-rhamnonate aldolase, KDR aldolase, 2-dehydro-3-deoxyrhamnonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
Protein: RS13_THET2
Sequence: MARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEAEVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQRTRTNARTRKGPRKTVAGKKKAPRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites (By similarity).
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: AMP1_PITHY
Sequence: LRPAVIVRTKAL
What is the function of this protein?
Has antimicrobial activity against the Gram-positive bacterium M. luteus.
What are the official names of this protein?
Antimicrobial peptide 1.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_VIBCM
Sequence: MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTIKDEIKGAVSSSIASTAKLEALGIRVYDCNDVSELDIYVDGADEINPERDMIKGGGAALTREKIVAAIAKKFVCIVDGTKAVDVLGNFPLPVEVIPMARSYVARELVKLGGDPVYREGVITDNGNVILDVYNMKITHPKDLESKINGIAGVVTVGLFAHRGADVVITGTPQGAKIEE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PDXA_SODGM
Sequence: MGSNQRIVITPGEPAGIGPDLVAALAQQAWPVELVICADPALLTARAQQLGLPLRLHSYRPEQPATPRPAGELTVLAIDTPAPVAAGELNVANSHYVVETLARACDSCLNGEFAALLTGPVHKGVINDGGLPFSGHTEYFAQRSGRERVVMMLATESLRVALATTHLPLLAVPGAVTRQSLDEVITILVHDLQQQFGIAQPCIYVCGLNPHAGEGGHMGREEIEVITPALDTLRAKGYNLVGPLPADTLFQPKYLQQADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAGSGQAEAGSIKTALNIAIDMIKHRNE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_STRU0
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMAQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDAQSGVEPQTETVWRQATEYRVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGSEDDFTGIIDLIKMKAEIYTNDLGTDIREEDIPAEYVDQANEYREKLVEAVAETDEELMMKYLEGEEITNEELMAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGVNPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLQSGSYVMNTSKGKRERIGRILQMHANTRQEIETVYSGDIAAAVGLKNTTTGDSLTDEKAQVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPLVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPSILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEARGNIQVVRAYVPLAEMFGYATILRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNHGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_BACHK
Sequence: MALTQERKNEIIAQFRTHETDTGSPEVQIAVLTEQINTLNEHLRTHKKDHHSRRGLLKMVGKRRNLLTYLRNSDITRYRELITKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PUR5_LACDB
Sequence: MIVNRYKDAGVDVNAGYELVRRIKGAVASTKRPGYVGNIGGFGGLFDLDSLGYDHPVLVSGTDGVGTKLIIAQKMDKNDTVGIDVVAMCVNDVLAQGAEPLFFLDYIACGHNDPALLASVVQGVAEGCKQAGASLIGGETAEMPDMYAPDEYDLAGFTVGVAEKDRLLSVDTPQAGDVLLGLASSGVHSNGFSLVRKILFKDHDVKLTDKPAELKGKSVGESLLAPTRIYIKSVLPLIKQGLVHGVAHITGGGLIENVPRMFNDGLRAEIAAGSWEVPDIFNYLKQVGNLSDDDCWQTFNMGLGMILAVPADKKEEAKQLLLASGEKVFEVGHLSERTDGEKIFIKLVE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHHB_XENLA
Sequence: MSDKLSYKVADISLADWGRKAIEIAENEMPGLMKMREMYSESKPLKGARIAGCLHMTLQTAVLIETLTAIGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGETDEEYIWCIEQTIYFKDGKPLNMILDDGGDLTNLVHTKYPQLLKGIKGISEETTTGVHNLYKMKSSGTLQVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRAFGARVLITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENMKDDSIVCNIGHFDVELDVKWLNDNAAKKINIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLGLDKEGPFKPDHYRY
What is the function of this protein?
Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (By similarity).  Binds copper ions (By similarity).
What are the official names of this protein?
Adenosylhomocysteinase B, AdoHcyase B, S-adenosyl-L-homocysteine hydrolase B.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSMC_ECOLI
Sequence: MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEKGTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKSEVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS
What is the function of this protein?
Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide.
What are the official names of this protein?
Peroxiredoxin OsmC, Osmotically-inducible protein C.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_I88A7
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGKWTINTETGAPQLNPIDGPLPEDNEPTGYAQTDCVLEAMAFLEKSHPGIFENSCLETMEVVQQTRVDKLTQGRQTFDWTLNRNQPAATALANTIEVFRLNGLTTSESGRLIDFLKDVMESMEKEEMEIVTHFQRKRRVRDNMTKKMVTQRTIGKKKQKLNRRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSVAPIMFSNKMARLGKGYMFESKNMKLRTQIPAEMLSSIDLRYFNDSTRRKIEKIRPLLIEGAASLSPGMMMGMFNMLSTVLGVSILNLGQKEYTKTSYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLLGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWDQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDKDYQGRLCNPLNPFVSHKEIESVNNAVVMPSHGPAKTMEYDAVATTHSWVPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEDFAEIMKICSTIEDLRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: HSLO_STRSY
Sequence: MDKIIKTLSKSGHFRAFVLDSTETVKTAQEKHDTMASSTVALGRTLIANQILAVNEKGDTKITLKILASGAVGAIISVANTKGQVKGYIQNPDLDYKRTATGEVIVGPLVGNGQFLVITDYGTGHPYNSMTPLISGEIGEDFAYFLTDSQQTPSAVGLNVLLDEEDKVKVAGGFLLQVLPGATEVEIARFEKRIQEMPAISSLLASENHIEALLSAIYGDDDFKRLSEEEIGFVCDCSKDRFLDALASLPKADLQEMKEEDKGVDITCQFCQTHYHFDENDLEELING
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BURTA
Sequence: MIGRIAGTLLEKNPPRILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPQERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHAADILNALLALGYSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: T2R38_MOUSE
Sequence: MLSLTPVLTVSYEAKISFLFLSAMEFAVGILANAFIVLVNVWDVVKKQPLNNCDIALLCLSITRLFLQGLLLLDAIQLACFQQMKDPLSHNYQAILTLWMIANQVSLWLAACLSLLYCSKIVRFSHTFPLHVASWVSRRFLQMLLVVLLLSCICTALCLWDFFCRSHSTVTSLLHLNSTEFSLQIAKLNFFYSFIFCNVGSVPPSLAFLVSSGVLVISLGSHMRTMKSQTSSSGDPSLEAHIRAIIFLISFFCFYVVSFCAALISIPLLMLWHNKGGVMICIGMMAACPSGHAAILISGNAKLRRAIETMLFWFQSRQKVRPVHKVPPRTL
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 38, T2R38, T2R138, mT2R31.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNMG_GEOTN
Sequence: MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGEMGKNIDKTYIQIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLTLLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFLRGEIIIGDIKYSSGPNNQQPSIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQLPCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPEGRETEEVYVQGLSTSLPEHIQRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETKLVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREEIILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRLQTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQVEIQIKYEGYIQKSLQEVERLKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQASRISGVNPADISILLVYLEQGRIARVSNE
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_XANOM
Sequence: MSKRDYYEVLGVARGASDEELKKAYRRCAMKHHPDRNPGDAAAEAAFKECKEAYEVLSDGNKRRAYDAHGHAAFEHGMGGGGGGPGSPDMGDIFGDIFGNIFGGGAAGPRAARRGADVGYVLELDLEEAVAGIERRIEIPTLIECVSCHGSGSEDGKVQTCGTCHGRGQVRIQRGIFAMQQSCPHCDGRGTLIQNPCKTCHGAGRVEENKVLSIKVPAGVDTGDRIRLAGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTADQRELLQQFEATFTGEDARKHSPKSATFIDGVKGFWDRMTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPA_CRIGR
Sequence: MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYISENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDLRGQPRYPVNSVNILKAHGRSQVESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIEKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLINGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPETKDDKHGSYENAVHSGALDD
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit alpha, TCP-1-alpha, 65 kDa antigen, CCT-alpha.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: DING_MYCTU
Sequence: MSESVSMSVPELLAIAVAALGGTRRRGQQEMAAAVAHAFETGEHLVVQAGTGTGKSLAYLVPAIIRALCDDAPVVVSTATIALQRQLVDRDLPQLVDSLTNALPRRPKFALLKGRRNYLCLNKIHNSVTASDHDDERPQEELFDPVAVTALGRDVQRLTAWASTTVSGDRDDLKPGVGDRSWSQVSVSARECLGVARCPFGSECFSERARGAAGLADVVVTNHALLAIDAVAESAVLPEHRLLVVDEAHELADRVTSVAAAELTSATLGMAARRITRLVDPKVTQRLQAASATFSSAIHDARPGRIDCLDDEMATYLSALRDAASAARSAIDTGSDTTTASVRAEAGAVLTEISDTASRILASFAPAIPDRSDVVWLEHEDNHESARAVLRVAPLSVAELLATQVFARATTVLTSATLTIGGSFDAMATAWGLTADTPWRGLDVGSPFQHAKSGILYVAAHLPPPGRDGSGSAEQLTEIAELITAAGGRTLGLFSSMRAARAATEAMRERLSTPVLCQGDDSTSTLVEKFTADAATSLFGTLSLWQGVDVPGPSLSLVLIDRIPFPRPDDPLLSARQRAVAARGGNGFMTVAASHAALLLAQGSGRLLRRVTDRGVVAVLDSRMATARYGEFLRASLPPFWQTTNATQVRAALRRLARADAKAH
What is the function of this protein?
Probable helicase involved in DNA repair and perhaps also replication.
What are the official names of this protein?
Probable ATP-dependent helicase DinG homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DinG subfamily.
Protein: IF2_ALTMD
Sequence: MADVSIEKLASDIGTTVDRLVGQFKDAGISKSAGEQVNEDEKQKLLDHLSKQHGSAAEPTRMTLKRKTTSTLSVGKSKEVKVEVRKKRTYVKRSDIEEQQRQAEEEAKRLEEEARLKREAEEKAAAEAKKAAEEKARKAQEAKKAAEEERVRRAEQAKKEAEARKKDEPELTEAEKAEAEAARQEEERLRKAQEEEAQKKLEEDAKKAADEARKLAEENERRWKEEEERRKKAEAEEVHLHSNRYAQEAEDEEDMQVERSSRRRRKSKKNAGEHLKQGFNKPAAPVERVVKLGATITVGELASKLAIKSNEVIKTMMKMGEMATINQVLDQDTAVLVIEEMGHKYELVNDNALEDELLADGTDGEKTSRAPVVTIMGHVDHGKTSLLDYIRRAKVADGEAGGITQHIGAYKVQTDNGEITFLDTPGHAAFTAMRARGATATDIVILVVAADDGVMPQTKEAVQHARAAGVPLIVAVNKMDKETADPDRVKTELSQLEVISEEWGGEHQFCNVSAKTGMGVDELLEAIVLQSELLDLQAVAEGPGRGIVIESRLDKGRGPVASVLVQEGQLRAGDILLCGEEYGRVRAMRDENGKDMKLAGPSTPVEVLGLSGVPVAGEDAAVVKDERKAREVAAKRHQKKRELKLARQQKAKLENMFANMESGDVSELNIVLKADVQGSVEAISESLIKLSTSEVKVNIVGSGVGGITETDATLAAASGAIVLGFNVRADATARRVLEAEEIDLRYYSVIYNLIDEVKAAMSGMLAPEFKQEIIGLAEVRDVFKSPKLGAIAGCMVTEGNVKRSNPIRVLRDNVVIYEGELESLRRFKDDVQDVRNGMECGIGVKNYNDVKVGDQIEVFEIVEVKREI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_CLOAB
Sequence: MKSKKSKFITKDILKEAIIESFKKLNPKYMMKNPVMFVVEVGFFVTILLTIFPSIFGDKGHNLRVYNLIVTIILFITVLFANFAESVAEGRGKAQADALKKTRKDTIAKLIGKDGSIKTINANELKKGDVVLVENGDVIPNDGEVVDGVASVDESAITGESAPVMKEPGGDFASVTGGTKVVSDWLKVEITATPGESFLDKMINLVEGASRQKTPNEIALNTILVSLTLIFLIVLVALYPMATYTGVKIPMSTLIALLVCLIPTTIGGLLSAIGIAGMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLAADFITVGGADKQKLIDYSVMCSLKDDTPEGKSIVELGKQLGITIDTKKYESIEFEEFTAQTRMSGIKLENGTAVKKGAYDAIKKRVQELKGVIPKDLDEAVNKVAKLGGTPLVVCVDNKIYGVIYLKDTVKPGLVERFERLREIGIKTIMCTGDNPLTAATIAKEAGVDGFIAECKPEDKIEAIKKEQDEGKLVAMTGDGTNDAPALAQADVGLAMNSGTTAAKEAANMVDLDSDPTKVLEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAIFTIAIPKMQLMNIMHLSTPYSAILSALIFNAIIIPALIPIAMKGVKYRPMKSEALLLRNMIVFGFGGIIVPFVGIKIIDMIITPMVRILNLG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_MARPO
Sequence: MDLVKYLTFSMILFLLGIWGIFLNRKNILIMLMSIELMLLAVNLNFLVFSVYLDDMMGQLFALFVLTVAAAESAIGLAILVITFRIRGTIAVEFINCMKG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.