PharMolix/UniProtQA huggingface dataset:
Protein: PSAC_PSEPI
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: GGPPS_DICDI
Sequence: MENSKIHFSYPLDKSDFKLIEPYTYICESSGKGFRNALIKSFDYWLKVGDEKVQDISKVIQGLHGASLLIDDIEDNSKLRRGKPVAHSIYGIPQTINSANFVYFLIMDQCNKLGDPKATTIFIEELIRLHRGQGYDIFWRDTNTSPSEQEYMNMVNEKTGGLFRLGLRLLQAFSDNNTNYIDLVEDLGMYYQIRDDLINLVSVDYQQNKSFCEDISEGKFSFPIIHAINADSNDNRLLRILKQKTEDRSVKEHALEYIKSKGSLEYTEKKLNVLKEKIIKQINDLGGNPILMKLMESLENSSI
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP11_MOUSE
Sequence: MSAAFRKAAKTRQREHRERSQPGFRKRLGLLEKKKDYKLRANDYHKKQDFLRALRKKALEKNPDEFYYKMTRAKLQDGVHIFKENKEEVTAEQLKLMRTQDIKYIEMKRVAEAKKIERLKSELHLLDFQGKQQKKHVFFFDTKKEVERFDVATHLQTAPELVDRVYNRPRIETLQKERVKGATPQTGLKRIAKERQKQYDCLTQRIEREKQLFVVAQKIQTRKDLMDKTQKVKVKKETVNSPAIYRFQTRRKR
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
Probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11, UTP11-like protein.
What is the protein family that this protein belongs to?
Belongs to the UTP11 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LPXD_BLOPB
Sequence: MIEMRLSDLAQQLNAKLHGDENIIITGVASINNAQVGHITFLKDQRFLSQLSSCRASAVILSKNNLIFCKIAALVVEDPYIAYVKIARLMDTTPKPSKNIASGAIIASDAILGQRVGIGANAVIESEVILGDDVIIGPGSFVGKKTRIGTGTRLWANVTIYHEVEIGECCLIQSGAIIGSDGFGYINDHGVWIKIPHLGTVKIGNNVEIGACTTIDRGTLDDTKIENGVIIDNQCQIAHNVIIGARTAIAGGVIMAGSLTIGRDCMIGGASVINGHINICDKVTITGMGMVIKAITQPGIYSSGIPVQLNTVWWKTAALIMRISNMNKRIKTIEEKLKKLLFL
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DHE3_THELN
Sequence: MVEQDPFEIAVKQLERAAQYMDISEEALEFLKRPQRIVEVSIPVEMDDGSVKVFTGFRVQYNWARGPTKGGIRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGVICNPKEMSDREKERLARGYVRAIYDVISPYTDIPAPDVYTNPQIMAWMMDEYETISRRKDPSFGVITGKPPSVGGIVARMDATARGASYTVREAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVSDSKGGIYNPDGLNADEVLAWKKKTGSVKDFPGATNITNEELLELEVDVLAPSAIEEVITKKNADNIKAKIVAELANGPTTPEADEILYEKGILIIPDFLCNAGGVTVSYFEWVQNITGDYWTVEETRAKLDKKMTKAFWDVYNTHKEKNINMRDAAYVVAVSRVYQAMKDRGWIKK
What are the official names of this protein?
Glutamate dehydrogenase, GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y139_UREPA
Sequence: MDEQIFIQLLENNLTNSKSYVTQPIILEFKTDVFLIINQILKQYKKGKIIKNNTNEIILEIDNKLISITNLDINKFHSYQIVNINENKNIYNERNSLILFDLVNYIIEKNQNSIRHINFWTIQMSVVNWIYFITYNFNNSYLIDPNWKKYVFKIKKDESKGVISTNLLHNYGFVDFVVQSKSQNFLKAYRVQDEILKSVLNLGDNLNNEFLEEIMRKYDTYKIIDRDHKYLVINIE
What are the official names of this protein?
Uncharacterized protein UU139.
Protein: RBFA_LACP3
Sequence: MKHRIGRVETQIQREVDDILLKDVNDPRVKGVTITGVKLTGDLQHATIFYSILDDAPDKVEAAQTGLDKASGLIRREVGQRIRLFKVPEIEFAQDKSVQYGARIDQLINEVRRKNLE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STT7_CHLRE
Sequence: MALAQRQVSCRIERSTGASTSQPVGSCLLVQRRPGQRRGVPARATPEFIDALSALVPNLPLEQIAAPCQVMKCGDIVYRSTLDPSLYNEAGFDEKTVALLAPVLAYLFLPPGVLPGAIDYYIRAPLKRKQTKAIDKNDIVLGKRLGTGGFGTVFKGELKEEGGVKTSIIIKKAKEFGEAEVWMNERMSRVAGHHVAEFVTAFDESLNVPLPAAAGKRAAPVQPTSPLDANSIWLVWVYEGDNTLSSLMERREWPYNLEPLLFGRELRAPRGPVRELVTIKEAFRQLVQAVAACHSVGIVHRDIKPANCIVSERDKKIKLIDLGAAADLRIGINYVPNEYLLDPRYAPPQQYIMSTQTPKPPPKPVAAFLSPILWTMEKPDRFDMYSCGITLLQMVFGHLRNDNALIAFNKRLQELKWDLPAWRREEEAKLPSAKGALAESLEAGFEALDADGGAGWDLLMRLLAYKPTDRPSAAAVLAHPWLTSAPGRTASLQHSLSGSFEATVSTAAAATSTALTAAGKSLGQAAKDAGLASMEEAILKVNQGALTEAQLMEELGLQEPAPVAPREGSQTIAWWQERQNELKARLVERREAMSESDPYGAAPSAMQVGSAINNARGGKGAKPTTPVKPTGPMAAAGAAAAAAAAAARVEAKVKVPNILGVKKPASGGGSNGRANGNGNGKAAPAKAANGNGSGNGNTNGNGNGAKQQLFGGLLGRKQQPVEEVQEEPEEEVEPEQETASKKERAFNLLGVFRR
What is the function of this protein?
Serine/threonine protein kinase required for state transition by phosphorylating light-harvesting complex II outer antennae (LCHII).  State transition plays a central role in response to environmental changes and allows to adjust to changing light conditions via the redistribution of light excitation energy between photosystem II (PSII) and photosystem I (PSI).
What are the official names of this protein?
Serine/threonine-protein kinase stt7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: DNLJ_CARHZ
Sequence: MDKEAVKKRIEELRALLHYHNYRYYVLDQPEISDAEYDRMLRELISLEQQYPEFITPDSPSQRVGGEVAKEFREVAHLKPMYSLDNAFGPEDLKEFDRRVRSLLPGQEVEYEVELKIDGLAISLVYENGVLVRGATRGNGTTGEDITANVKTIKAIPLKLRNPIPLLEVRGEAYMPKESFARLNEQREERGEPLFANPRNAAAGSLRQLDPKVTAERDLSAFMYAIGEVQGYEPKTQAELMEWLSELGFKVNPYREVFNNIDDVINYCQSWHEKRFSLPYVIDGLVIKVNSLAQQEALGFTAKSPRWAIAYKFPAEIAETRLKDIIVRVGRTGVLTPTAIFEPVSLAGTTVTRASLHNEDYIREKDIRIGDIIRVQKAGEIIPEVVEVVKEKRTGAEKEFVMPDTCPVCQGKAVRLPGEAAWRCTNASCPAQLKEGIVHFASRGAMNIEGLGPAVAELLLEAGLIHNYADLYYLSAEEVARLPRMGKKSAENLINAIEKSKQNSLERLIYGLGIRLVGEKAARDLAVHFKELDKLIAAGEEEIMAIPSVGPKMAASIKAFFAQKENLELIEKLKAAGVNTKYLAEVRDNRLEGLTFVLTGTLSSFTRKEAEQLILSLGGKVSSSVSKKTSYVVVGEDPGSKLTKAKELGIPILTEEEFRQMVMS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: COAE_ALIF1
Sequence: MSYVVAITGGIGSGKTTVADRFQALYNINIVDADIIAREVVNPGTEGLIQIEQHFGPQILLDDGHLNRAKLRECIFSEPSEKQWLNDLLHPLIRSEMQRQIALSTSEYTLLVVPLLVENKLQYLANRVLVVDVLEQTQINRTVNRDKVNHQQVKAILASQASREERLAAADDIINNDHKIMT
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBP1_CASGL
Sequence: MALTEKQEALLKQSWEVLKQNIPAHSLRLFALIIEAAPESKYVFSFLKDSNEIPENNPKLKAHAAVIFKTICESATELRQKGHAVWDNNTLKRLGSIHLKNKITDPHFEVMKGALLGTIKEAIKENWSDEMGQAWTEAYNQLVATIKAEMKE
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Hemoglobin-1, Hemoglobin I.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: PBP7_SHIFL
Sequence: MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND
What is the function of this protein?
Cell wall formation.  May play a specialized role in remodeling the cell wall.  Specifically hydrolyzes the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi (By similarity).
What are the official names of this protein?
D-alanyl-D-alanine endopeptidase, DD-endopeptidase, Penicillin-binding protein 7, PBP-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S11 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NCEH1_HUMAN
Sequence: MRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL
What is the function of this protein?
Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (PubMed:17052608).  May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (By similarity).  Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity).  May contribute to cancer pathogenesis by promoting tumor cell migration (PubMed:17052608).
What are the official names of this protein?
Neutral cholesterol ester hydrolase 1, NCEH, Acetylalkylglycerol acetylhydrolase, 2-acetyl MAGE hydrolase, Arylacetamide deacetylase-like 1.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Microsome.
Protein: YA57_NATPD
Sequence: MVEIQTGLRENTVGAVEQFAEIASIDPLVASMILSGAIIITVAVVAFGALTLGAIGASIKRGLSGSEEPNQPA
What are the official names of this protein?
Uncharacterized protein NP_1057A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL34_NEIG2
Sequence: MKRTYQPSVTKRKRTHGFLVRSKTRGGRAVLAARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NU5M_ONCMY
Sequence: MHPTTLILSSSLLMIFTLLIYPLITTLTPTPQHKNWALTHVKTAIKMAFLVSLLPLFVFLDQGTETIVTNWQWMNTTTFDINLSFKFDHYSIIFTPIALYVTWSILEFASWYMHADPNMNRFFKYLLLFLIAMIILVTANNMFQLFIGWEGVGIMSFLLIGWWHGRADANTAAMQAVIYNRVGDIGLILSMAWFATNLNSWEIQQMFASSKGLDLTLPLMGLILAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRLHPLMEDNQTALTVCLCLGALTTLFTATCALTQNDIKKIVAFSTSSQLGLMMVTIGLNQPQLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGMHNLTPSTSSCLTIGSLALTGTPFLAGFFSKDAIIEALNTSHLNAWALTLTLLATSFTAIYSLRVIFFVSMGHPRFTATAPVNENNPSVINPIKRLAWGSIIAGLLITSNFLPTNTPVMTMPTHLKLAALLVTISGLLIALELASLTNKQFKLHPTLTLHNFSNMLGFFPAIIHRLTPKLNLTLGQTIASQMVDHTWFEKVGPKELFQLTCLMVTTTSNIQQGMIKTYLTLFFLSTTLAVLLTLT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SURE_SYNAS
Sequence: MRYLLTNDDGIYARGLSALYSELSKDADCLIVAPEVERSAVGHAITLNRPLMVRRTKKDGNFLGYAVSGTPADCVKIGIKELSEKPVDLVVSGINIGANVGINVIYSGTVSAATEGAILGVPSMAISLGTLRNADYTFAAHFARTMARFIMKYFEKKSVALNINVPALPVQDIKGYAVTRQGKARLIESFDRRVDPRERLYYWLAGETQLSEQEEPDSDGSALSRGMISITPIYHDMTRYDALDGLKALLSKETSLLPVAKCDFQD
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAPN_SACS2
Sequence: MEKTSVLIKSKELMEIYELKDGVPYFKTYLSGQWISGDEWQDVISPIDLNIIGKIPKLNWNQIDDTLEHIYRKGRWSIRDTPGEKRLDIYKKMASLLDKFKEDFVNVLMINNGKTKSAAEGEVKAAIERLLRADLDVKETRGDYVPGDWSSETLETEAVVRKEPVGVVLSIVPFNYPLFDTVNKIVYTTVIGNAIIIKPPSSTPLPILMLAKVMELASFPKDSFAIITIPGRDMNKVVGDKRIQAISLTGSTETGEEVVRNAGIKQFIMELGGGDPAIVLSDADLAWAAQRIAAGIISYTGQRCDSVKLVLVEEEVYDTLKDLLIKELTKSVKVGDPRDPLTTVGPVIDVKTVDEWEKAIKDAVEKGGKILFGGKRLGPTYIEPVLIEAPKETLKDMYFYNKEVFASAALLIKVKNIDEALEISNSRKYGLDAAIFGKDINKIRKLQRFLEVGAIYINDYPRHGIGYFPFGGRKDSGIGREGIGYTIQYVTAYKSIVYNYKGKGIWEYL
What is the function of this protein?
Catalyzes the irreversible NAD(P)-dependent non-phosphorylating oxidation of glyceraldehyde-3-phosphate (GAP) to 3-phosphoglycerate (3PG).  It is highly specific for D-GAP.
What are the official names of this protein?
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde phosphate dehydrogenase (NAD(P)), GAPN.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: OSPG_SHISS
Sequence: MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
What are the official names of this protein?
Protein kinase OspG, Effector protein OspG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cell.
Protein: TRPC_ACIBT
Sequence: MINIQNTILGKIVDRKHEELAARLKQRNLQDVEELAKAATPVRGFANALQHKRPGVIAEIKKASPSKGIIRADFNPAEIAQQYEQAGAACLSVLTDVDFFQGADENIAIARNHCALPALRKDFLVDPYNVVEARALHADCILLIVACLSDQQLEEMSKTAFEHQLDVLVEVHDEEELERALKLSEQCLLGVNNRNLKTFDVDLNTTIRLKKLLPASRLLITESGIATPDDVRMMQEHDIHSFLVGESFMKQPRPDQAFTALFGQPQTV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TRUB_THEP1
Sequence: MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNATEEEIREAIFSFVGEYDQVPPAYSAKKHKGERLYKLAREGKIINLPPKRVKIFKIWDVNVEGRDVSFRAEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGSYTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKTILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKHERNERVLTLRKVFNTR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SBP1B_XENLA
Sequence: MAKCGSCGPGYKSPLDAMKGPREEIVYLPCIYRSTGINKPDYLATVDVDPKSPTYSQVIHRLPMPNVNDELHHSGWNTCSSCYGDSSKVRNKLILPCLISSRVYVVDVGTDPRAPRLHKTVEPHEVYWKCGLANLHTSHCLGCGEIMISALGDPCGNGKGGFVLLDGETFEVKGNWEAEGETAQFGYDFWYQPRHNVMISTEWGAPKAFALGFKMEDVLAGQYGHSLNVWDWTEHRLVQTIDLGKDGLIPLEIRFLHNPDADQGLVGCALSSSIFRFYKEKDGKWAAEKVIQVPSKKVEGWALPEMPGLITDILISLDDRFLYFSNWLHGDIRQYDITNIRNPKLVGQIFLGGSIQKGGPVAVQEDKELECQPDPVTVKGKIIPGGPQMIQLSLDGKRIYVTSSIYSIWDKQFYPDMLKEGAVMLQIDVDTEKGGLKLNPNFLVDFGKEPDGPVLAHELRYPGGDCSSDIWI
What is the function of this protein?
Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (By similarity).  Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm.  May be involved in intra-Golgi protein transport (By similarity).
What are the official names of this protein?
Methanethiol oxidase, MTO, Selenium-binding protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the selenium-binding protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: LPR1_ORYSJ
Sequence: MRAKVELAVLLLVLVGVAAGTRPPSAPPPVTEDTLQKVAGSLEMYVDELPQMPKIYGFSMRHGHPSPIRLTIGMYQKKWKFHRDLPASTVFVFGTSAATATFPGPTIEAAQGVPLSVTWQNYLPARHILPWDPTVPTAIPRRGGVPTVVHLHGGAHPPQSDGSAFAWFTAGFGETGPAWSTPTYTYPNAQSPGVLWYHDHALGLTRANLLAGLLGAYVIRNPAVEAPLGLPCGDEFDRVLMLADRSFYADGSIYMNYTGIIPNIHPQWQPEYFGEAITVNGKAWPFLAVARRRYRFRIINTSNARYFNLSLTNGLPFTVVGSDTNYLSKPVTAASLLVSVAETFDVVVDFSQSTSSEAELVNTAPYPYPDGQAPNDLNGKVMKFVISPAKAKDTSRVPAKLLDYVAVAEEEAVQRRYIVMYEYEDAATGNPTHLYINGKRLEDPATETPRPGTTEVWEVINLTPDNHPLHLHLATFQATRVRGLVDEDAFKGCMAKLNDAVRCNVSRHAVGEEVAVPEHEKGWKNVVKIAPGYMTTIVVKFFMVDSGKPYPFDATAEPGYVYHCHILDHEDNAMIRPLKLIK
What is the function of this protein?
Multicopper oxidase that may play a role in the maintenance of inorganic phosphate homeostasis.
What are the official names of this protein?
Multicopper oxidase LPR1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CAPZB_CAEEL
Sequence: MGEQQLDCALDLMRRLPPQHCDKNLTDLIDLCPHLVDDLLSTIDQPLKIAADRETGKQYLLCDYNRDGDSYRSPWSNTYDPPLEDGQLPSEKRRKMEIEANAAFESYRDLYFEGGVSSVYFWDLDNGGFAGIVLIKKEGDGAKNITGCWDSIHVIEITERARQAHYKLTSTIMLWLQTNKSSSGVMNLGGSLTRQHEMDAPINDQNTHLANMGRMIEDQESKMRLTINEIYFGKTKKVMSDLRSTEKQSELEKQDEIVRELNNAMANRGN
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
What are the official names of this protein?
F-actin-capping protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SYY_ERWT9
Sequence: MASSNLIKQLQERGLVAQVTDENALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQDAGHKPVALVGGATGLIGDPSFKAAERKLNTSETVNQWVEKIRQQVAPFLSFNCGDNSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNERYGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKSDGTKFGKTEGGAVWLDAAKTSPYKFYQFWINTADADVYRFLKFFTFMSLEEINQLEEEDKSSGKAPRAQGVLAELVTRLVHGEEGLIAAQRITRSLFAGNVTELTANDLSQLAQDGMPGIELKIGQDLQQALVNAELAPSRGQARKLIEAKSVSINGSLQTDAEYTFGEDDRLFGQYTLLRRGKKNYSLISWQS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_STRTD
Sequence: MEIKGLRKIEPYVAGSQPAEKNIIKLNTNENAYGPSPAVHQALASFDAHQLRKYSTLDQTALRQALSDQLGVPTDQFIIGNGSDDILSMAFLAFFNSEEKIIFPDLTYGFYKVWADLYRIPFREVPLTSSFEIDTQDYLVENGGIILTNPNAPTGIYKPLDQVEEIVKANQSVVVIIDESYINFGGETALPLLEKYDNVFITRTFSKDASLAGLRVGYGIGSPKLMAVINAVKNSVNPYNVDSIAEALGTAAVRSWDYYEDICAKIMATRDWFSQELQAIGFDVLPSKTNFVLVKPYGVTAGQLFAYLQSKKIYVRYFPKVERISDRLRISIGTQDEMERVLMTIQELQA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: COX3_MOUSE
Sequence: MTHQTHAYHMVNPSPWPLTGAFSALLLTSGLVMWFHYNSITLLTLGLLTNILTMYQWWRDVIREGTYQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGISPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGKRNHMNQALLITIMLGLYFTILQASEYFETSFSISDGIYGSTFFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.