PharMolix/UniProtQA huggingface dataset:
Protein: HSP82_TOBAC
Sequence: EFISYPIYLWTEKTTEKEISDDEDDEPKKDEEGAVEEVDEDKEKEKGKKKKIKEVSHEWQLINKQKPIWLRKPEEITKDEYASFYKSLTNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTRKKMNNIKLYVRRVFIMDNCEELIPEYLGFVKGVVDSDDLPLNISREMLQQNKILKVIRKNLVKKCIEMFNEIAENKEDYNKFYEAFSKNLKLGIHEDSQNRAKLADLLRYHSTKSGDEMTSLKDYVTRMKEGQKDIYYITGESKKAVENSPFLERLKKKGYEVLYMVDAIDEYAVGQLKEYDGKKLVSATKEGLKLDDDSEEEKKKKEEKKKSFENLCKIIKDILGDKVEKVVVSDRIVDSPCCLVTGEYGWTANMERIMKAQALRDSSMSSYMSSKKTMEINPDNGIMEELRKRAEADKNDKSVKDLVLLLFETALLTSGFSLDDPNTFAARIHRMLKLGLSIDEEEEAVEDADMPALEETGEESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_BRUO2
Sequence: MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTWPLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COX7R_BOVIN
Sequence: MYYKFSGFTQKLAGAWASDAYSPQGLRPVVSTEAPPIIFATPTKLSSGPTAYDYAGKNTVPELQKFFQKSDGVPIHLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASQPRNK
What is the function of this protein?
Involved in the regulation of oxidative phosphorylation and energy metabolism (By similarity).  Necessary for the assembly of mitochondrial respiratory supercomplex (By similarity).
What are the official names of this protein?
Cytochrome c oxidase subunit 7A-related protein, mitochondrial, Cytochrome c oxidase subunit VIIa-related protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: INT6B_XENLA
Sequence: MPILLFLLDTSASMNQRSHLGTTYLDIAKGAVETFMKLRSRDPASRGDRYMLVTLEELPYGIKAGWKENHATFMNELKNLQAVGLTTLGQSLRTAFDLLNLNRLVTGIDNYGQGRNPFFLEPSIIVAITDGSKLTTANGVQDELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGATAVEQEQPTAVQFDESPITAMCDVTGGRSYSVTSQRILNQCLESLVQKIQSGVVINFEKSGPDPPILEDGLTDPVRSVGSQPWHSCHKLIYVRPNPKTGVPIGHWPIPESFWPDQNSPTLPPRTSHPVVKFSCTDSEPLVIDKLPFDKYELEPSPLTQFILERKSPHTCWPVFVPNSAKYCELGHPFGYLKASTALNCVNLFVLPYNYPVLLPLLDDLFKMHKNKPPLKWRQPFENYLKTMPPYYIGPLKKALRMMGTPNLMPDSMEYGLSYSVVSYLKKLSQQAKVESDRVIGSIGKKYPQETSIKVRSGSNALSLALRKDFKQLLQEITGEVPQRPMDLNMKEFAGFQIALLNKDIKPQTFRNAYDIPRTNLLDHLTRMRANLLKSTRQFLKGQDEDQAHSIPIVQMGNYQEYLKHIPSPLRELDYDQPRRLHTFGNPFKLDKKGMMIDEADEFVSGNQNKLKRTGEPNMQGVPKRRRCMSPLLHSRPQSPSVINNHISGKDSPVSVNQVLCDLPKPVAVHKNTDMSNNVAINEATENHVADHLCDDLLITKSESFGTLPNAALEASESYAAGGDSNFSPNDTSDVLLDKTRESGDTESCLLNNNTAFVHRKRRLHQCRSYEEANIELKAQILKEIRKPGRKYGIIFTLLKDVQGDLQTRLLFLQHVIKEATRFKKRMLIEQLEGFLEEIHRRTNQVNHLSSC
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 6-B, Int6-B.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MMAD_HUMAN
Sequence: MANVLCNRARLVSYLPGFCSLVKRVVNPKAFSTAGSSGSDESHVAAAPPDICSRTVWPDETMGPFGPQDQRFQLPGNIGFDCHLNGTASQKKSLVHKTLPDVLAEPLSSERHEFVMAQYVNEFQGNDAPVEQEINSAETYFESARVECAIQTCPELLRKDFESLFPEVANGKLMILTVTQKTKNDMTVWSEEVEIEREVLLEKFINGAKEICYALRAEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHLGFSVDDLGCCKVIRHSLWGTHVVVGSIFTNATPDSHIMKKLSGN
What is the function of this protein?
Involved in cobalamin metabolism and trafficking (PubMed:18385497, PubMed:23415655, PubMed:24722857, PubMed:26364851).  Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl) (PubMed:18385497, PubMed:23415655, PubMed:24722857).  Promotes oxidation of cob(II)alamin bound to MMACHC (PubMed:26364851).  The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine (PubMed:27771510).
What are the official names of this protein?
Cobalamin trafficking protein CblD, CblD, Methylmalonic aciduria and homocystinuria type D protein, mitochondrial.
Protein: GAG_FIVSD
Sequence: MGNGQGRDWKMAIKRCSNVAVGVGGKSKKFGEGNFRWAIRMANVSTGREPGDIPETLDQLRLVICDLQERREKFGSSKEIDMAITTLKVFAVVGLLNMTVSTAAAAENMYTQMGLDTRPSTKEAGGKEEGPPQAYPIQTVNGAPQYVALDPKMVSIFMEKAREGLGGEEVQLWFTAFSANLTPTDMATLIMAAPGCAADKEILDESLKQLTAEYDRTNPPDGPRPLPYFTAAEIMGIGLTQEQQAEARFAPARMQCRAWYLEALGKLAAIKAKSPRAVQLRQGAKEDYSSFIDRLFAQIDQEQNTAEVKLYLKQSLSIANANAECKKAMSHLKPESTLEEKLRACQEIGSPGYKMQLLAEALTKVQVVQSKGSGPVCFNCKKPGHLARQCRDVKKCNKCGKPGHLAAKCWQGGKRNSGNWKAGRAAAPVNQVQQTVMPSAPPMEEKLLDL
What is the function of this protein?
Nucleocapsid protein p13 encapsulates and protects viral dimeric unspliced (genomic) RNA.  Binds these RNAs through its zinc fingers (By similarity).
What are the official names of this protein?
Gag polyprotein.
What is the protein family that this protein belongs to?
Belongs to the feline lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p13]: Virion.
Protein: ISPH_ECOLC
Sequence: MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEKLSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGKSAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DXR_CHRVO
Sequence: MTKPQGIAVLGATGSVGCNTLDVVARHPERYRVVALTAHRQLDKLFEQARRFCPDYLVVADADAAARLRARLAEAGLRSEVLHGADALVQVAALPEVDAVMASIVGAAGLPSALAAARAGKRILLANKESLVVAGRLFMDAVRASGSALLPVDSEHSAIFQSLPADYAGNPDGAGVRKIILTASGGPFRNRPAADLAHVTPDEACRHPNWSMGRKISVDSATLMNKGLEVIEARWLFNVPPSRIEVAVHPQSVIHSMVQYRDGSVMAQLGSPDMRTPIACALAWPERIDAGVEPMDFFSLSDLTFEKPDLERFPCLQLAFDALEMGGDAPAVLNAANEVAVAAFLAGRLRFVDIPRVVAASLSGVSCAASDSLEGLLARDEEARRFAEGGVAAC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RIMP_ACIBS
Sequence: MKLSNKSQALYDMIAPAVEACGVDLWGIEFLPQGKRSLLRIYIDRTVDENAEPVINEDGEVEQGRGIGVEDCVRVTQQVGAMLDVHDPISGEYALEVSSPGWDRPFFQLEQLQGYIGQQVALRLIAAVENRRKFQAKLLAVDLENEEIQVEVEGKHVLDIDSNNIDKANLIYQD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BRUME
Sequence: MTVGLFGGSFNPPHGGHALVAEIAIRRLKLDQLWWMVTPGNPLKDSRELAPLSERLRLSEEVAEDPRIKVTALEAAFHVRYTADTLALIRNANPDVYFVWVMGADNLASFHRWQRWREIAQNFPIAIIDRPGSTLSYLSSRMAQTFSDSRLDERYAPVLARRMPPAWTFIHGPRSSLSSTALRKVQLKKAPSKK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MOAC_NATTJ
Sequence: MVDEFTHLDNQGKARMVEINQKPDTSRRAVARGSIYMKANTLQKVKTNEMEKGDVLGVARVAAIMGTKRTGDLIPMCHPLMLTGIEVNFNFDEENCKIDIEVIVKTTGKTGVEMEALTGVSLAALTIYDMCKSIDKTMKIEHIRLAKKSGGQSGEIENE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RYK_HUMAN
Sequence: MRGAARLGRPGRSCLPGARGLRAPPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSASAGPSVSLYLSEDEVRRLIGLDAELYYVRNDLISHYALSFSLLVPSETNFLHFTWHAKSKVEYKLGFQVDNVLAMDMPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMCYKKLEEVKTSALDKNTSRTIYDPVHAAPTTSTRVFYISVGVCCAVIFLVAIILAVLHLHSMKRIELDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSYPTLRIEKNDLRSVTLLEAKGKVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV
What is the function of this protein?
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A.  Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth.  In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
What are the official names of this protein?
Tyrosine-protein kinase RYK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus.
Protein: CMS1_YEAST
Sequence: MSNPDDLDDGLAYDFDAEHEVIFDAKDGSPPTKKVQKRSIEQDDDDVDDIDGKKEERNSEDDSNRPISKRQKKLQKKSKLIEKKKEESQYIVSQRKALPASSPEKIIEYLTTLIREKNPDLSVLELEELYFKRNDFLSTEKFDAERRLSNFPAFIQKFSVAPKKIVFSMSNIRVADVYRSLNGGKNCVKLFSKSKLKDDIATVERLLTDSSKKSNKNKDSLYFIATPTRMQKIIEATDLLFQGKEKLDIILDASYLDPKDNTILSFENAAVLCQVLKTFLNKKSSVKILLY
What is the function of this protein?
May play a role in the regulation of DNA replication and cell cycle control.
What are the official names of this protein?
Protein CMS1, Complementation of MCM10 suppressor protein 1.
What is the protein family that this protein belongs to?
Belongs to the CMS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RT17_MOUSE
Sequence: MSIVRSSVHAKWVVGKVIGTAMIKTAKVRATRLVLDPYLLKYFNKRKTYFAHDALQQCSVGDIVLLRALPVPRSKHVKHELAEIIFKVGRVIDPVTGKPCAGTAYLESPLSEPREELKVS
What are the official names of this protein?
28S ribosomal protein S17, mitochondrial, MRP-S17, S17mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ECOT_SALG2
Sequence: MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKRQVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSPVSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQNAVAR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DEOD_ESCF3
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: BI1_DICDI
Sequence: MASTSNRNFFSSNMTQIPMDEKIRIALQFNNLSQSTKQTLTKVYCALAIGILTATVGVLFSMFIYRPGFLMTLLLVIGSAILFATTPRTQDYKTQVKRFTLFNLVTFVTGMSSSGLIELYMDINSSIVLNAFMATCGIFISFTLFSLLTNKRLYIFIGSSLASLSIGIFVLALTRLFGGYSEPLDQLFILAILASSVLFIIFDTQIMVHRIENLGEKDVLFHAFILFYDFVDLFRVILKILAKKENKNNNKSRR
What are the official names of this protein?
Bax inhibitor 1 homolog, BI-1.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MSBA_SHESM
Sequence: MTASPKDEMWTVFKRLLGYLKPMKGMFLLSVCGLIVYGLVDAAFISFIGPFIDKGFSSSTPAISNGIALPTSQGFHADNQVLLMAPIVVILMFSLRGFANFVSTYGISYMSARLIMDMRQQVFEHYLSLPVSYMDKENTGNLISKVTFDTEQIARASGSALISIVRDGVTVIGMLGLMFYNSWKLSLCILVIGPIMGLVITIVSRRFRKVSKQIQTAMGDVSAATEQMIKGHKNVLAFGGQETETARFAKINDRNRHQNMKLAVAQAVSQPLIMVIGSFALAFVLYAASLDSMKADLTAGTFATILGAMMAMLQPIKNLTRVNAEFQRGIAACTTVFELLDTLPESDTGTYTVKRAKGNLRFDNVSFSYEGQERRALDKIDFEVTQGQTLALVGRSGSGKSTIASLVTRFYTGLESGDIKLDDVSIYDYSLKSLRSQVALVSQQVTLFNDTIANNIAYAYPGEATREQIIQAATLAHAMEFIEQLPEGLDTQVGENGVLLSGGQRQRIAIARAMLRDAPVLILDEATSALDTESEKAIQQGLDNLRQNRTSVVIAHRLSTIESADQILVVDQGRIVERGTHKSLLELGGMYAKLYQMQFGS
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DDB1_DICDI
Sequence: MYNFVSTVQKPTSVTHSVTGNFTGPNDKNLIISKCTKIEIFLMDQDGLKPMFDVNIYGRISVLKLFSVAGSKQDYLFISTESFKFCILAYDYEKKEIITKASGNAEDTIGRPTEAGQLGIIDPDGRIVALHLYEGLLKLITLDNNNTPNKINNNNNNNNNNNNNNNNNNNNNINNNNFNINNNNNNSPIQKNVNNVRLEELQVLDMTFLYGCKVPTIAVLFKDTKDEKHISTYEISSKDTELVVGPWSQSNVGVYSSLLVPVPLGGVLVVADNGITYLNGKVTRSVAVSYTKFLAFTRVDKDGSRFLFGDHFGRLSVLVLIHQQQKVMELKFEQLGRISIPSSISYLDSGVVYIGSSSGDSQLIRLNTEKDQTTDSYVTYLEAFTNIGPVVDFCVVDAEKQGQAQIVTCSGTYRDGSLRIIRNGIGIAEQASIELEGIKGIFPINNNNNNNNNNNNNNNNNNNNNSNGITDSKDRYLITSFIECTKVLSFQGEEIEETEFEGLESNCSTLYCGTIDKLNLLIQITNVSINLIDSNTFKRVSQWNVEPSRRINLVSTNQDQIVLSIDKSLLYFQINSSNKSIQLVKEIELPHEISCIDISPFDSFMDTKSQLVSVGLWNDITLRIFKLPTLEEIWKEPLGGEILPRSILMISFDSIDYIFCSLGDGHLFKFQFDFSSFKLFDKRKLTLGTQPIILKKFKLKNTINIFAISDRPTVIYSHNKKLFYSVVNLKDVTNVTSFNSDGFPNSMAIATTNSLTIGTIDEIQKLHIKTIPLNEEMGRRIVHLEDHSCYAVITVKNNEGLLGGAQDLCEEDEEVSYIRIYNDQTFELISSYKLDPYEMGWSITPCKFAGDDVNTYLAVGTSINTPIKSSGRVLLFSLSSSSSSNDKDSLDNNNNNNNNSGANGKLTLLEEIKFRSSVYFLLSFNGRLIAAVHKRLFSIRYTHSKEKNCKVISSESVHKGHTMILKLASRGHFILVGDMMKSMSLLVEQSDGSLEQIARNPQPIWIRSVAMINDDYFIGAEASNNFIVVKKNNDSTNELERELLDSVGHYHIGESINSMRHGSLVRLPDSDQPIIPTILYASVNGSIGVVASISEEDFIFFSKLQKGLNQVVRGVGGFSHETWRAFSNDHHTIDSKNFIDGDLIETFLDLKYESQLKAVADLGITPDDAFRRIESLMQYIR
What is the function of this protein?
Plays a role in DNA repair.  May be a component of an E3 ubiquitin-protein ligase which promotes histone ubiquitination in response to UV irradiation.  Histone ubiquitination may be important for subsequent DNA repair (By similarity).
What are the official names of this protein?
DNA damage-binding protein 1, DNA repair protein E, UV-damaged DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RH20_ARATH
Sequence: MSRYDSRTGDSTSYRDRRSDSGFGGTSSYGSSGSHTSSKKDNDGNESPRKLDLDGLTPFEKNFYVESPAVAAMTDTEVEEYRKLREITVEGKDIPKPVKSFRDVGFPDYVLEEVKKAGFTEPTPIQSQGWPMAMKGRDLIGIAETGSGKTLSYLLPAIVHVNAQPMLAHGDGPIVLVLAPTRELAVQIQQEASKFGSSSKIKTTCIYGGVPKGPQVRDLQKGVEIVIATPGRLIDMMESNNTNLRRVTYLVLDEADRMLDMGFDPQIRKIVSHIRPDRQTLYWSATWPKEVEQLSKKFLYNPYKVIIGSSDLKANRAIRQIVDVISESQKYNKLVKLLEDIMDGSRILVFLDTKKGCDQITRQLRMDGWPALSIHGDKSQAERDWVLSEFRSGKSPIMTATDVAARGLDVKDVKYVINYDFPGSLEDYVHRIGRTGRAGAKGTAYTFFTVANARFAKELTNILQEAGQKVSPELASMGRSTAPPPPGLGGFRDRGSRRGWS
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 20.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAU1_PYRAB
Sequence: MSTESEISVRIRGIYSTALTKLFLDKGFKIVQPSDVIAERLGIEKSYEDFDVDIYDRNHGITIVGTKVEEVRKALEEELVDVFFRKLPYKLYGVYKGIVVKRDDRYVYVDIGNAIGTVLVEELPDAVEGDEVVVQVKKHNVLPHLSIMITIPGDYAVLIPKPIGVQRHVKISRKIRDPEERERLRILGLSVNLGEWGILWRTAAAYKEWSLLRDELVRLSKIADKLKEADKYSAPAEIIEGRSIYEVEFGGGAKKKLDEIRNRVVPTIEGHHQYKSYDPEFTLAVEVAEGILAKMPSQRQKISEGFVEAITNSKGPRVGWIFTLNHVKPDGQVIKIGPGEVIEVSSRPLRVKIRRNLRPGRVYDGLEVPIEPGDYAITEIEAGKWWFVHRYYDRNGNLKGEFYNINTPVEIYPDKARYVDLEVDIVKWPDGKKEIIDKEKLKEHYEDGIISEKLYKAVLRIVQEVYERV
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: MPGP_PYRAB
Sequence: MIKVIFLDIDKTLIPSYDPEPAEPVIKELKRKGFEIVFNSSKTRAEQEFYREKLDVKTPFISENGSAIYIPKNYFPFEIKGRETKDYIVIELGVKVEEIRRELRKLEDAYGIKYYANSTKEEIMEFTGMPEELVPLAMEREYSETIFKWSRESWKRTLSERGFTVTMGSRFYSVHGNCDKGKAAKILLELYRRLGPVRSYAVGDGYNDFPMFDVVDRAFLIGNLTHEKAQNVSSIMEVLEVIE
What is the function of this protein?
Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG).
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEFE_STRCL
Sequence: MDTTVPTFSLAELQQGLHQDEFRRCLRDKGLFYLTDCGLTDTELKSAKDLVIDFFEHGSEAEKRAVTSPVPTMRRGFTGLESESTAQITNTGSYSDYSMCYSMGTADNLFPSGDFERIWTQYFDRQYTASRAVAREVLRATGTEPDGGVEAFLDCEPLLRFRYFPQVPEHRSAEEQPLRMAPHYDLSMVTLIQQTPCANGFVSLQAEVGGAFTDLPYRPDAVLVFCGAIATLVTGGQVKAPRHHVAAPRRDQIAGSSRTSSVFFLRPNADFTFSVPLARECGFDVSLDGETATFQDWIGGNYVNIRRTSKA
What is the function of this protein?
Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
What are the official names of this protein?
Deacetoxycephalosporin C synthase, DAOCS, Expandase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: IF2_ACIBY
Sequence: MTDKSIKELALSVGRPVEKLLEQAREAGLPQRTADDIITTEQQDTLVNYLKKVHGQESGNTGKIALKRKTTSTAKVASTSGKAKTINVEVRKKQVFAKPNPEQIAAEAKARAEAEAKARAEQQAREAAEQKARLQTEQKAKATLDAMRAAHQQDSAAQSAPKAAVVVKKRGGGTVKPAPKPAETLEQKKAREAQTAQLKATEEAARRKAAEEAQQRTLEQMRKMASKYSNDDATATIRVIDDSPLASGLVGQAYEDSFNQEDREIKRGGATTNPRAGKKGGRRGQEEQSFVNHNKRGLKSSQANKHGFEKPVKKQVYDVEIGSSIVVADLAQKMAIKVREVIKTLMKMGELVNQNQTIDQDTAALVVEEMGHNPVLVSDTQAEDNLLEAAEEARGEQTTRPPVVTIMGHVDHGKTSLLDRIRRSKVAAGEAGGITQHIGAYHVETDKGIITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTAEAIDHARAAGTPIIVAINKMDKESADPDRVLNELTTKEIVPEEWGGDVPVAKVSAHTGQGIDELLDLILIQSELMELKASAEGAAQGVVIEARVDKGRGAVTSILVQNGTLNIGDLVLAGSSYGRVRAMSDENGKPIKSAGPSIPVEILGLPEAPMAGDEVLVVNDEKKAREVADARADREREKRIERQSAMRLENIMASMGKKDVPTVNVVLRTDVRGTLEALNAALHELSTDEVKVRVISSGVGAITESDVILAESSEAVLLGFNVRADTAARQKSDQDGIDIRYYSIIYELIDDVKDAMSGKLAPEHRETILGVAQVREVFRSSKFGAAAGCMVMEGVIHRNKPIRVLRDDVVIFQGELESLRRYKDVVDEVRAGMECGLAVKGYNDIKPLDKIEVYDVQMVKRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SYNE7
Sequence: MSRFRIGNGYDIHRLVEGRPLILGGIQLEHSLGLDGHSDADVLTHAIMDALLGALSLGDIGHYFPPTDPQWKGADSLKLLAQVNQLIRDRGWTIGNLDSVVVAEQPKLKPHIAAMRDRLAKVLELEPDQIGIKATTNEKLGPTGREEGICAYAVALLVRD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: OTC_PHOLL
Sequence: MNPFHQRHFLRLLDFSSAEIHALLKLAAELKSTKKSGTEKALLTGKNIVLIFEKDSTRTRCSFEVAAYDQGANITYLGPSGNQIGHKESIKDTARILGRMYDGIQYRGYAQTIVESLAKYAGVPVWNGLTDEFHPTQLLADLLTIQEHQPEKPLSEIKFAYLGDARNNMGNTMLEAAALTGMDVRLIAPEKYWPNAALVTECQKLAEKTGGKITLTENITEGVKNTDFLYTDVWVSMGEPKDVWQQRVHLLKPYQVNMDVVSMTGNPQVKFLHCLPAFHDEETALGKQLAAEFNMYGGLEVTNEVFESEHSIVFDQGENRLHTIKAVMVATLANDLKI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.