PharMolix/UniProtQA huggingface dataset:
Protein: KXCA_DICDI
Sequence: MVGGLPNSSLWNIEYDDLVFKDIIGKGNFGCVYRGNYLGVEVAIKQIPSFDDPDYCKYTEREVKALRYIRHPFVVHFFGACKHESGFYLITEFIEGLDLRRYLKSVPKPPKWLSRVNIALGVAKTFLFLHSKNLLHRDLKSKNILLDISRNQIKLCDFGFARVGSQYSNGSDSSSSEDESDSECVNGAAGGGGDDVYKNNGNGKPANYRLRRMSICGTPSFMPPEILLQQKYDWSVDVFSFGILCTELITLKRPGKDYWVRSQNNGFDINIEELNVNIPSPNDCPIQFYDLALKCCSYKHTNRPMFSTIVTILESIKLQLELFENQQQQQQLQQQQQLQQQQQQQQQQQQQQQQQLQLQQQQSSESSSSSSSQPLVNNNNNNSNCNNNNFNNSSNNNNSIANNDSISNVSTTTTSIPTTTTTTTTTTTTTNNITAINGTSNKYLQPLSKHQQQQQRNQNSSIIDNNSLIGSSNTESMITSFSISTFKERKKQSLNKLIRANTINILIGQQQQQQQQQQQQQQQQQDNQSSSQNQLIEREGVIKLDTTKYPNGWKEFGIDNSTNKIWIIYQSNIIKIGSNNNNNLIEMTCGTIIKLKKHSITLSIVDSNLISGANIINVKSYLKDYPYVNKPIKVNQQQQQQQQIITNNYELNLIIKLQSRIRGWLVRRRYKIFLSNWKLNNSNTSQSNKNQWIRLFNQLISSELEYKKQLDQVIKSYLLPIQSKFRINKPLLNYKEIGSIFSNIESLSEIHNELLKIVNQISKSPFFIMNFENEKDDRSNQNNTSATTDIFGDSSIQFTNISINTKDSSNQINSITQFIVKNISQIKNQYGIYAFNFKYSTNIYNWCRLNPDFSIFCDTIRSQLNQQFPDQENDLASLLSLPINKIQKYLLVFEKLAQITPITHSEYKDIKSAFTLIRETSNYIQSQLEMSFEHSHIMSIDIMLQKKDNQSLMQSGRWFIRQGQFTELSSNKQYYLFLLSDICLITKPIKSKSSKYNNNNNINTNNNNNNLTSSATQTNSNKDLSTSINQSTSNANSDNSGNNNNNLINSKYYYRLKTIINLKEEVSMRINPDISNGVLFIGPNKTYKWLLPNDEEAKDWVNDFERTTILIYRNNPNGGGSNNNSIGGGGGGRGGSGNNSNNGSIDLTEINQIHHINNQAIPLSSSNNNITNNNSINNNIIMNNNNNNNKDTEGKGFIKRFRLSFSAGTSTPERKTSLVNMSPSTTSSLNNIDSNYNNNNNNVTNTPIKSVTSSPSIHYTPVNDNNQQPQLPSQPNEEFQFTVPTTPSDKKKKRGSFSSKLKRLSITFSKD
What are the official names of this protein?
Kinase and exchange factor for Rac A, Serine/threonine-protein kinase kxcA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: RUVC_MYCLE
Sequence: MRVMGVDPGLTRCGLSVVENGRGSQVVALDVDVVRTPSDAPVSKRLLAVSDVVEHWLDAHHPDVMAIERVFSQQNVSTVMGTAQAGGVIALAAARRGIDVHFHTPSEVKAAVTGNGAANKAQVTAMVTRILALQAKPTPADAADALALAICHCWRAPMIARMAEAEALGARHRQAYRAKVAGEVKATR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: H32_TETBO
Sequence: MARAKQTARKSTGAEAPRKQLASKAARKSAPATGGIKKPHR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: STHC_PHANO
Sequence: MAPAETTGNVQRPEAGKQSMGSFWTQMFPPKPTYTEEQVPDLTGKIFIVTGSSSGVGKEAARMLYAKNAKVYMAARPGPKLPAAINSVQEAVPKSGGALIPLELDLADLAVVKKAVEKFTSLETKLHGLINNAAVQALKDTDGDARTAQGHEIHMGVNVLAPFLFTRLLTGVLTATARQEPPGTVRVVWVSSMGTETIGEKRRGLSPDYVDYWPLMSPLERYGLSKAGNWLHGVEFARRYAADGIASFPINPGHLKSDLYREGGALFKFALKPVLYPPTYGAYVELFAALSPTLTLKDSGAWSKYVEMVYFPDC
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the phytotoxin stemphyloxin II (PubMed:31553484).  The first step of the pathway is the synthesis of dehydroprobetaenone I by the polyketide synthase sthA and the enoyl reductase sthE via condensation of one acetyl-CoA starter unit with 7 malonyl-CoA units and 5 methylations (PubMed:31553484).  The C-terminal reductase (R) domain of sthA catalyzes the reductive release of the polyketide chain (PubMed:31553484).  Because sthA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase sthE (PubMed:31553484).  The short-chain dehydrogenase/reductase sthC then catalyzes reduction of dehydroprobetaenone I to probetaenone I (PubMed:31553484).  The cytochrome P450 monooxygenase sthF catalyzes successive epoxidation, oxidation (resulting from epoxide opening) and hydroxylation to install a tertiary alcohol in the decaline ring to yield betaenone C from dehydroprobetaenone I and betaenone B from probetaenone I (PubMed:31553484).  The FAD-linked oxidoreductase sthB is responsible for the conversion of betaenone C to betaenone A via an intramolecular aldol reaction between C-1 and C-17 to form the bridged tricyclic system in betaenone A (PubMed:31553484).  Finally, the cytochrome P450 monooxygenase sthD catalyzes the hydroxylation of C-15 to afford the final metabolite stemphyloxin II (PubMed:31553484).
What are the official names of this protein?
Short-chain dehydrogenase/reductase sthC, Stemphyloxin II biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: YCCC_SCHPO
Sequence: MYRPTTTSYSPVYTGNPLYDISASQSDPRQRIRKNVRFQTEVDEFPDFDDSDSDELQFENRDPRKRIDPIKHMLLVQRLKRVSTSSRRLFIFTLSMFLIAFILLIAFVSFRD
What are the official names of this protein?
Uncharacterized protein C1795.12c.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PVK1_PERSS
Sequence: GSTGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PerSc-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2190_RALSO
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEITVAARLGGGDVDSNPRLRLAIDKGTDANMPKDNIQRAIQRGVGGLEGAHYEEIRYEGYGISGAAIIVDCMTDNRTRTVAEVRHAFDKHGGNMGTQGSVAFMFDHVGQFIFAPGTPEDKLMDAALEAGAEDVVTNDDGSIEVLCPPNDFAKVKAALEGAGFKAELAEVIMKPQTEVEFTGDDAAKMQKLLDALENLDDVQEVYTNAVIGE
What are the official names of this protein?
Probable transcriptional regulatory protein RSc2190.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH1_MYCUA
Sequence: MSLGAADVGAGAGPPGQHAGAVDNWPVAIIGSGVVGTDLMSRIGNGDGRLRVSAMVGTNPHCDGLARAAAAGISTSPGGVDGLLSMPEFANIRLVFDTTNPGAHQSNWARLADTGVRMLDLTASAIGPCCVPAVNLDAQLDAPNLSMATCSAQAAVPIVAAVRRHGVVRYAEVVSAIASQALGPAERVTLDEFAELTTTAVQELGGARRAKTLTIVNPADPPMPMRTTVFCLVDQADEVARNEADVLAVVDGVQALLPGYRLKHRVQFERLGSGNTLYIPGTGEFGGTRITVLLEITAAGGYLPACAGNVAIVTSAAKATAEAIVERHAQTLKAKI
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: AC4CH_ECOSM
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAGQENMTLPELKKVIADIYPGQIQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: Y266_MYCPN
Sequence: MLKKKVNNDAGKTFILISSSCSSCQKAIEYFKENNLSYTIENFYKKPISDKRFRDILSLSEDGTESLFSKRADQIRSNTNQSVEDLTIPELIKLIRERPSILRRPIIIQYNSSGIPKRMRIGYNAAEIKVFERSLMEPKVRTVKK
What are the official names of this protein?
Uncharacterized protein MG127 homolog.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.
Protein: PXR1_KLULA
Sequence: MGLAAARNKQRFGLDPRNTTWSNNTSRFGHKHLEKLGWKPGSGLGLVPDSTTSHIKVSIKDDNLGLGAKLKKKEKQDEFDSGECTGLDVFQRLLGRLNGNEQTISDELDKQRTDNIINGKWGIHFVKGEVLASTWDAENKQLISYSMGKKRPVEGSSDSEVSDRKKTKKVKKEKKVKKVKKEKKEKKEKKDKKEKKVKKEKKEKKEKKLKDKHSKDTNEITRDQMLKPRDSAAVVPDAVSTRLSVRAKWIRQKRAAVMDAKALNEIFMVTD
What is the function of this protein?
Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
What are the official names of this protein?
Protein PXR1, PinX1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the PINX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KAX83_LEIHE
Sequence: VSCEDCPDHCSTQKARAKCDNDKCVCEPI
What is the function of this protein?
Specific and potent inhibitor of ClC-2/CLCN2 chloride channel.  It slows ClC-2/CLCN2 activation by increasing the latency to first opening by nearly 8-fold but is unable to inhibit open channels, suggesting that this toxin inhibits channel activation gating.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 8.3, Gating modifier of anion channels 2, Toxin GaTx2, Leiuropeptide II, LpII, Leiuropeptide-2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MINC_YERPE
Sequence: MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: OBG_VIBCH
Sequence: MKFVDEAVIKVQAGDGGNGVVSFWREKFVTNGGPDGGDGGDGGDVYMVADENLNTLIDYRFQRFYEAERGKNGGGGNCTGKSGKDKELRVPVGTRAVDIHTNEIIGEVAEHGKKVMIAKGGWHGLGNARFKSSVNRSPRQKTLGTKGELRDIRLELLLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVSVLPEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHMIDIMPADQSDPAHNALTIIDELEQYSEKLAKKPRWLVFNKVDLMSEEEADEIIQNIIDALAWEGDYFKISAANRQGTKELCMKLAEFMDTLPREAEEKTEAEKVDFTWDYNHKDGLAGREVITEDDDDWDDWDDEEDDGHVIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control (By similarity).  GTPase activity is stimulated by 50S ribosomal subunits (PubMed:25912137).
What are the official names of this protein?
GTPase Obg/CgtA, CgtA, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_VIBVU
Sequence: MDKKASRIRRATRARRKIAELGATRLVVHRTPRHVYAQVIAANGSEVIAAASTVEKAIREQVKYTGNIEAAKAVGKAVAERALEKGVSTVAFDRSGFQYHGRVAALADSAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PPR3B_XENTR
Sequence: MPWISSHMNSSSVLDFFPHKTMAVDIAMKFYLRSPPLRRDRVECRIARKSNEPLRPCIQTTNKTLLSELSNQENKVKKRVSFADSRGLALTMVKVYSDFDDELEIPFNISELIDNIVNLTTVEKERFFLDFVQPSADYLDFRNRLQAESVCLENCMLKDKALVGTVKVKNLAFQKSVKIRMTCDSWQTYKDYDCLYVKDTYAGSDKDTFSFDVSLPEGIQSSASIEFAVCFECEGRIFWDSNKGLNYRIVRQDHRIPSDFESRHYDPVCLSVDQYGSPRCSYGIFPELQTYSGFDKLGPYY
What is the function of this protein?
Acts as a glycogen-targeting subunit for phosphatase PP1.  Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity.  Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3B.
Protein: IAN8_ARATH
Sequence: MANDQKNSESFPAKEDHKKDDAAAPAEVDHKDEFSASQPHPVENIVLVGRTGNGKSATGNSIVRSKVFKSKTKSSGVTMECHAVKAVTPEGPILNVIDTPGLFDLSVSAEFIGKEIVKCLTLADGGLHAVLLVLSVRTRISQEEEMVLSTLQVLFGSKIVDYLIVVFTGGDVLEDDGMTLEDYLGDNMPDFLKRVLILCGQRMILFDNKTKDDEKKTKQVHELLKLIDLVRKQNNNIPYTDEMYHMIKEENERHKKEQEELESKGHSEEQLAALMKELQIMNERNLKAMAEMMEKNMKIAMEAQEKLFEQREKAQEMSYQQKMEMQEKLKQMEGRMRAEMEAQMLSRQQCSIL
What are the official names of this protein?
Immune-associated nucleotide-binding protein 8, AtIAN8, Protein AIG1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Protein: LSPA_CLOD6
Sequence: MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVENRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDRVRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SQMT2_BOTBR
Sequence: MAVDLLSIYGPGLFESLLTVKGATGLIAALILGYIIITRLPGQKTKPKLLDLTAGGIPFEKVGEVFNDYDKSYGKGTHGELHVQDTNKVFQLANTFYDFVTDGYEWAWGSSFHFSQRMPGLSHAASQMLHESRMASYLRLKPGMTCLDVGCGVGNPGRTVAACSGAVVTGITINKYQIQRAEYHNRRTGLVGFFKPTVGNFCNMPFDAKSFDAAFAMDATCHAPKLEDVYGEVFRVLKPGGFFATYEWVSTKNYDPTNTRHVKVMNSIIFGNGLPNIRSWKQAEEAGENVGFKLLTSFDLATAPPVGKPWYYVPELMVKYGLLKIQKALVRGACSLGLLPDQSWKVCNMVADMVPNLVEGGATDIFTPMHLLIFQKPE
What is the function of this protein?
Converts squalene to mono- and dimethyl derivatives, but not to tri- and tetramethylated products.  Unable to methylate cycloartenol, zymosterol or lanosterol.  Methylates both C-3 and C22 positions, but only C-3 position in monomethylated products.  Produces mainly monomethylated squalene and only 20% of dimethylated squalene.
What are the official names of this protein?
Squalene methyltransferase 2, Triterpene methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: CBID_LISMF
Sequence: MEDFIYYNGKKYRKGYTTGTCAAAAAKACVEMILTQEEVSAVQVTTTGGTILEIPVAYQKFSKDKATAAVQKDGGDDIDATHGMWIFVDVDLTDNAEVVLDGGVGIGRATQKGISVAVGEAAINPAPRKNILATVRESLGENRGAKILVYAPEGEERAKRTMNSNLGIIGGISILGTTGIVTPMSDEGWKKSLSMELEMKRNQGLDQIILVPGNYGDDFVQNTLGFSSGNIVSMSNFVGYMLKETQRLAFKKVLMVGHFGKLVKVSAGIFTTYSKDADARAEILVANLALLGAPLSLLQAVEKCNTTEAAGELIEEAGFTQVYDVIVQKIKARSERFLKFTKPSVEVDVVTFSTERGLLAATKDIDVLREEWR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: TTYH3_HUMAN
Sequence: MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSH
What is the function of this protein?
Probable large-conductance Ca(2+)-activated chloride channel.  May play a role in Ca(2+) signal transduction.
What are the official names of this protein?
Protein tweety homolog 3, hTTY3.
What is the protein family that this protein belongs to?
Belongs to the tweety family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_VIBPA
Sequence: MEVRHNWTHAEVRDLMEKPFMDLLFEAQLVHRQYQQTNHVQVSTLLSIKTGACPEDCKYCPQSARYTTDIEKERLMEVERVLDAAQKAKNAGSTRFCMGAAWKNPKERDMPHLTDMIKGVKDMGLETCMTLGMLTPEQAKQLANAGLDYYNHNLDTSPEFYGNIITTRTYQDRLDTLSHVRDAGMKICSGGIIGMGESANDRAGLLVELANLPTHPESVPINMLVKVKGTPLETVDDVDPFDFIRLIAIARIMMPQSAVRLSAGRENMNEQMQALCFMAGANSVFYGCKLLTTPNPSEDKDMMLFKKLGINSQEVSQKPDEIEENELLDRVVERVAARPTKDDLFYDASV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KA11N_SCOPC
Sequence: MNKVHFALFLLVLTVLAVSGFPSENAPTGGCPLSDNVCSSYCKKNKFGNEGKCHGTICKCSIK
What is the function of this protein?
This recombinant toxin selectively inhibits mouse voltage-gated potassium channel Kv1. 3/KCNA3 (IC(50)=24. 73 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTX 11 Sp4, KTX-Sp4.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 11 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_EDWI9
Sequence: MTLERTFSIVKPNAVAKNAIGAIYARFESAGLKIVAAKMVHLTREQAEGFYAEHRERPFFDGLVTFMTSGPIMVQVLEGNDAVRRNREIMGATNPESALAGTLRADYADSLTENAVHGSDSPASAEREIAYFFSADDICPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH35_MOUSE
Sequence: MRETPEREEEPGTEAPCAASCHAQRILQTLNAYRRSGTLTDVVLRAGGRDFPCHRAALSAASAHFRGLFAAGRPERAAAVVPVGPETPGTAAALAVVLDYVYGAGVRLRAEDEAAAVLALAERLGVAGLREACARFLEGRLRAANSLALRRVAAAFSLASLAERCGRVLRQAFVEVTRHADFLELAPDEVAALLADPALRVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADELLQACGDCRPLLLEARACFILGREAGALRARPRRFMDLAEVIVVIGGCDRKGLLKLPFADAYHPESQRWTPLPSLPGYTRSEFASCALRNDIYVSGGHINSRDVWMFSSHLNTWIKVASMHKGRWRHKMVALQGQLFAVGGFDGLRRLRSVERYDPFSNTWAAIAPLPEAVSSAAVAPCAGQLYVIGGAGQDGVNTDKVQCFDPKEDQWSLRSPAPFLQRCLEAVSLEDTIYVVGGLMSKIFTYDPGSDVWREAADLPSPVESCGVTVCDGKVHILGGRDEHGESTSSVFTFDPGTGQVEAQPSLQRCTSSHGCVTIVQSLSR
What are the official names of this protein?
Kelch-like protein 35.
Protein: ENGB_MESH2
Sequence: MVKCKLFFWLISWFLKVKNGEKVWKFLKSCPENCYSEPQFAFIGRSNVGKSTLINALANKKIAKTSTKPGRTQLLNFYKNESEKLFVDLPGYGYAAVSKTKKHQIDRIIAGYFQKDQPISAVFLILDARVGFTNLDYIMIEYIIQQGFKLHILANKIDKTNQSTRAILLNQCKKLKLNCLLISAKNKNNLSKLQELLE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: LGT_MANSM
Sequence: MENQFLAFPQFDPIIFSLGPISLRWYGLMYLIGFIFARWLAVKRANRPDSGWTVEQVDNLLFNGFAGVFLGGRIGYVLFYQWDLFVQEPSYLFRVWEGGMSFHGGLIGVIVAMLVTAKLQKRNFWVVADFVAPLIPFGLGMGRIGNFINDELWGRVTDVPWAVLFPSGGYLPRHPSQLYEFVLEGIVLFCILNWFIRKPRPAGSVAGLFLLFYGLFRFIVEFFREPDAQLGLYFGQQISMGQILSTPMILLGALFIVLAYRRRSAVKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GTR5_PONAB
Sequence: MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVAKSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLVLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPKEHVQFVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLVACCVLTAALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEKEELKELPPVTLEQ
What is the function of this protein?
Functions as a fructose transporter that has only low activity with other monosaccharides.  Can mediate the uptake of deoxyglucose, but with low efficiency.  Essential for fructose uptake in the small intestine.  Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose.  Required for the development of high blood pressure in response to high dietary fructose intake.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 5, Fructose transporter, Glucose transporter type 5, small intestine, GLUT-5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Note=Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A.
Protein: RL32_JANSC
Sequence: MAVPKSKITRSKRGMRRAHDALVAANPNECPNCGELKRPHHVCPSCGYYNEREVIAQDEVDLDEDAA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: EMTA_SALTY
Sequence: MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL21_AMOA5
Sequence: MYAIVEIAGKQFKVTKDLYIYTPKMDQEAGSSVSFDKILLLQNDQDIQVGDPTVAGAKIEGKVIEHVKGDKIIVFKRKRRKGYKTKQGHRQGYTKVLIQNILR
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.