PharMolix/UniProtQA huggingface dataset:
Protein: RSGA_FLAJ1
Sequence: MTGTVYKSTGSWYTVKSEKGDFVECRMKGKFRIKGIKSTNPIAVGDIVDYELDETSDAVTGTIHTIHERKNYIVRKSVNLSKQIHIIASNIDQVFLLVTIDNPPTTTSFIDRFLVTAEAYGIEAILIFNKIDTLNEQTLDDQLYLQHIYTEIGYKCLRISSTENKGVDKLKEMMVGKVSMFSGHSGVGKSTLVNAMEPSLHLKTSVISEQSKQGQHTTTFAEMYDLSFDARIIDTPGIKGFGIVDMEPTEISGYFPEFFKLKDQCKFNNCLHKEEPHCAIKAALEKDEIAWSRYNSYLKILEGDEEHYRTDIYGEDRAASDETRK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_STAAE
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNEVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LIPA_ECOLU
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPFD_MYCTO
Sequence: MTPGLLTTAGAGRPRDRCARIVCTVFIETAVVATMFVALLGLSTISSKADDIDWDAIAQCESGGNWAANTGNGLYGGLQISQATWDSNGGVGSPAAASPQQQIEVADNIMKTQGPGAWPKCSSCSQGDAPLGSLTHILTFLAAETGGCSGSRDD
What is the function of this protein?
Factor that stimulates resuscitation of dormant cells.  Has peptidoglycan (PG) hydrolytic activity.  PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity (By similarity).
What are the official names of this protein?
Resuscitation-promoting factor RpfD.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. Rpf subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS15_VIBVU
Sequence: MSLNAETKAAIVADYARGEGDTGSPEVQVALLTASINHLQGHFQAHKGDHHSRRGLLRMVSRRRKLLDYLKGKDLARYQDLIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PYRD_AGRRK
Sequence: MIGSFRDLGRRGLFLLDPETAHGMSIAALKSGLVPTCRVSNDPRLRQIVAGLDFANPLGMAAGYDKNAEVPEALLKLGFGFTEIGTVTPKPQPGNPRPRIFRLVEDEGVINRLGFNNEGHEAALRRLQPIRGNGIIGVNIGANKDSADRIADYVAGIRRFYSVARYFTANISSPNTPGLRDLQARESLSALLSAVLAARDDEAAKAGKKIPVFLKIAPDLTEEGMDDIAAEVLAHALDGLIVSNTTLSRDGLKDQVQAKEAGGLSGKPVFERSTVVLAKMRRRVGAALPIIGVGGVSSAETALEKIRAGADLVQLYSCMVYEGPGLPGRVVAGLSKLLDRERVASIRELRDSRLDYWADRKV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEM1_FRATT
Sequence: MNMALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLRVVDDILVWWQGYVRNPNYKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGHCPVSVAFSAITLAKRQLDNISSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSAFRNASAHYLSELPQLIKKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVKSLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKIRNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDCLVCMKRMFGLNVEK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DAPA_VIBVY
Sequence: MLSGSIVALLTPFKADGEVDFDGLQKLVEYHIAAGTNGIVAVGTTGESSTLTVEEHVKVVNKTVEFVNGRIPVIAGTGANATHESVTFSRLLNDSGIDACLSVTPYYNKPTQEGLFQHYKAIAEVSNVPQILYNVPGRTAVDLLPETVARLAELENIVALKDATGDLNRVAIHRELCGEDFILLSGDDATGLDFVKLGGQGVISVTNNIAAKDMADMFRLALEGRFEEAEVINQRLMPLHKNLFIESSPIPVKWAATQLGLIECGHLRLPLTELSEKCHPIVAQAMTDAGIY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPDB_STRP6
Sequence: MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLXGRTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVYDEAGFNECGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALIAKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDFNDKENTIASEDVEKVAKKAKSYIEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDSKVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVKGYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAYQEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEIKGLEKTWIAEQDKTTKEISDLVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVKEKPKNKKGLNRS
What are the official names of this protein?
Probable dipeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family.
Protein: AMPA_ECOBW
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI1_CERS4
Sequence: MARTSAIDYGRAAKYFLLLDFIKGFGLGMKYFFAPKHTVNYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIDAEPREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETREELFYNKDRLLENGARWEAEIARNLELDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DED1_ASPFU
Sequence: MADSLKMGNLSLNESQHAPAAPPSNGRAAYIPPHLRQRTMGANVDGAAASPPGPAPGAGAWNGPRNAPRGGNWANANASDFSPRGPNVPNGNISWTPTETQRRPFNPHAYGHPGHGGSYGGSHGSAKGSGDGQWRDGKHIPGPANARLERELFGVPNDPTKQSTGINFANYDDIPVEASGHDVPEPVNAFTNPPLDDHLISNIKLARYQTPTPVQKYSIPIVMNGRDLMACAQTGSGKTGGFLFPILSQAFQTGPSPVPAQASGQFGYGRQRKAYPTSLILAPTRELVSQIFDEARKFAYRSWVRPCVVYGGADIGSQLRQIERGCDLLVATPGRLVDLIERGRISLVNIKYLVLDEADRMLDMGFEPQIRRIVEGEDMPNVNERQTLMFSATFPRDIQMLARDFLKDYVFLSVGRVGSTSENITQKVEYVEDHDKRSVLLDILHTHGTSGLTLIFVETKRMADALSDFLLNQRFPATAIHGDRTQRERERALEMFRSGRCPILVATAVAARGLDIPNVTHVINYDLPTDIDDYVHRIGRTGRAGNTGIATAFFNRSNRGVVRELIDLLKEAHQEVPSFLESIAREGSGYGGRGGRGGRGRGGNATRDMRRMGGNVGGGGPSFGGGYGAPSGSSYGGGAGGYGAPPAYGGGYGGGYGGGSYGNPSGPTGPSSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase ded1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_FRATM
Sequence: MKILLANPRGFCAGVSRAVETVEKVLEVEKSPVYVRHEVVHNKVVVDSLKKKGVVFVKEVDEVPDDAVCIFSAHGVSLKVEEAAAKKNLVLYDATCPLVTKVHRGVRLASNNDAECILIGHKGHPEVQGTMGQYRSKKGAIYLIESEEDLNKLTIKDPDNLYYATQTTLSVDETQGIIQALKDKYPNIKGPKKEDICYATQNRQTAIKAMLKHIDVLVVVGSQNSSNSNRLKELATLEGIDAYLVDNPKDVDKLWFDNKKVCGVSAGASAPEYLVQQIISQISKVCSTEVEEFEGIKEEVYFPLPRLLKQKIGTGKVE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RR4_GOSHI
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRAGSDLRNQSRPGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPQARQLVNHRHILVNGRTVDIPSYRCKPRDIISARDEQKSRTLIQNYLDSSTNEELPKHLTFHTLQYKGLVNQIIDRKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DXS_BRUSI
Sequence: MSRPSTPLLDKAPTPDRLRALPEQDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYDRIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAAKQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANAPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGTGLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGSVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGATGLSTTVADARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFGSHVLQFLATDGLLDRGLKVRALTLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRDELGHEALPTPFRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PAX_I36A0
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGENLKIETNKFAAICTHLEVCFMYSDFHFINEQGESTIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKTDYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREEKRQLKKGLKSQEQCASLPTKVSRRTSPALKILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: Y1350_BURO1
Sequence: MLRYAIIFFIIAIIAAVFGFGGIAAGAAEIAKILFYIFVVIFLVTLLLGVVRR
What are the official names of this protein?
UPF0391 membrane protein Bcen_1350.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
Protein: CH601_BURVG
Sequence: MAAKDVVFGDSARSKMVEGVNILANAVKVTLGPKGRNVVLERSFGGPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDNAGDGTTTATVLAQSIVREGMKYVASGMNPMDLKRGIDKAVAAAVEELKKISKPCTTNKEIAQVGSISANSDSSIGDRIAEAMDKVGKEGVITVEDGKSLADELDVVEGMQFDRGYLSPYFINNPDKQVAVLDNPFVLLHDKKVSNIRDLLPVLEQVAKAGRPLLIIAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKAMLEDIAILTGGQVIAEETGLTLEKATLAELGQAKRIEVGKENTTIIDGAGEAASIEARVKQVRTQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALIRARTAIAGLTGANADQNAGIKIVLRAMEEPLRQIVTNGGEEASVVVAAVAAGKGNYGYNAATGEYVDMVEAGVVDPTKVTRTALQNAASVAGLLLTTDAAVAELPKEDAPMPGGMPGGMGGMGMDM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGB1_VIGUN
Sequence: MVAFSDKQEALVNGAYEAFKANIPKYSVVFYTTILEKAPAAKNLFSFLANGVDATNPKLTGHAEKLFGLVRDSAAQLRASGGVVADAALGAVHSQKAVNDAQFVVVKEALVKTLKEAVGDKWSDELGTAVELAYDELAAAIKKAY
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation (By similarity).
What are the official names of this protein?
Leghemoglobin-1, Leghemoglobin I, LbI.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: AMPO_MOUSE
Sequence: MDIKLDPSRDDLPLMANTSHMLVKHYILDLDVDFGNQVIEGNIVLFFGDGNRFKNQSRSTQETFQMESEEADIFRTAEPCHVPEMDSSTFSPKMGHRECAVCGKGDQDAFDNDGNHDNQERDSEISSSKYCCDTGNHGKRDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTKAPKLLATPEKLRCEIVRDLVALPADAWREQLDCYTRCSQAPGCGELLIDSDNWSLRIRKTGTSTPADFPRAIRIWYKTKPEGQSVAWTTDQNGRPCVYTMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTPLREGYMSWHYYVTMPMPASTFAIAVGCWTEMKPKASPPDDLMTEHSLPLSPSEADLRYDNTCNHMEYPCRFQSASAASQDIIPYRVFAPVCLEGACQEALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFPSLGMASPHIIFLSQSTLTGTSHLCGTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELRNSPEGMQVLRPNKEETGHVSASGASVVKHGLNPEKGFMQVHYLKGYFLLRFLTRTLGEKIYFPFLRKFVHLFHGQLILSQDFLQMLLENIPENKRLGLSVENIVRDWLECSGIPKALQEERKAEDCSPSRLARQVGSEVAKWIRVNRRPRKRKRGKREVAFEKLSPDQIVLLLEWLLEQKTLSPQTLHCLQQTYHLPEQDAEVRHRWCELVIKHKYTKAYNQVERFLLEDQAMGIYLYGELMVSEDARLQQLAHRCFELVKEHMDRASAQVVTEMLF
What is the function of this protein?
Aminopeptidase which catalyzes the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates.
What are the official names of this protein?
Aminopeptidase O, AP-O.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: DMRT1_DANRE
Sequence: MSEEEQTNGSLSIRKPSRMPKCSRCRNHGFVSPLKGHKRFCNWRDCQCQKCRLIAERQRVMAAQVALRRQQAQEEEMGICSPINLSGSDTLVKNEAVGENVFTLSSGPPSPASSSATASPTNLGSRSMLSLSPAMSSRGHTDCTSDLMVDASYYNLYQPTPYSSYYSNLYNYQQYQMPSGNGRLSSHNVSPQYRTHSYYSSYLSQGLGAACVQPSTCPEPKAAAFSDGAQDSVSISSMINAENKLECESSSESGSFSVDSIIEGATK
What is the function of this protein?
Transcription factor that plays a key role in sex determination and differentiation by controlling gonad development and germ cell proliferation.  Acts both as a transcription repressor and activator (By similarity).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COABC_VIBVY
Sequence: MQTLAGKKILLGISGGIAAYKCADLTRRLKERGAEVQVVMTKAAKEFITPLTMQAVSGRPVSDSLLDPAAEASMGHIELAKWADLILLAPATADLIARMAAGMGNDLLTTLVLATDAPVAVSPAMNQQMYRNVATQENIATLSRRGMEIWGPAAGEQACGDVGPGRMLEPMQLVALCEQFFQPKPLQDKSILITAGPTREAIDPVRYITNHSSGKMGYALAQAAMQLGANVTLVSGPVSLPTPVNVNRINVDSAQEMYDAVMAQASDHDIFISCAAVADYRPATIAEQKLKKTDDSDEMTITMVKNPDIVASVSAMTENRPFTVGFAAETNDVEVYARRKLEKKKLDLLCANDVSVEGQGFNSSDNAITLYWPQGEKALPLNSKAALSMEILKQIQTLMGH
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: HEM6_RICRS
Sequence: MNIENKEITSSWFTNLRDLLCKEFEKIEEEYAQTKGLKPAKFVRSSWQRNGGGGGVMSLMKGAVFEKVGVNISTVFGKISPEFRNEIPGAELDGKFFATGISLVAHLKSPLIPAMHFNTRYIETSKSWFGGGGDLTPFYPEKNETVKFHAAFKEVCDKYDSSYYPKFKKQCDEYFYLKHRKEPRGVGGIFYDYLNNGNFEQDFAFTQDVGKTLLSVYPEIVRSKLFLPWTAEQKEYQLIRRGRYVEFNLLYDRGTKFGLMTDGNVEAILMSLPPEVKFN
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDH1_HUMAN
Sequence: MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQVGQPFQLSTPQPLPHPYHGAIWTEVWE
What is the function of this protein?
May be involved in cell-cell interaction processes and in cell adhesion.
What are the official names of this protein?
Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42.
What are the subcellular locations of this protein?
Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell- cell boundaries and probably at cell-matrix boundaries.
Protein: THMS2_HUMAN
Sequence: MEPVPLQDFVRALDPASLPRVLRVCSGVYFEGSIYEISGNECCLSTGDLIKVTQVRLQKVVCENPKTSQTMELAPNFQGYFTPLNTPQSYETLEELVSATTQSSKQLPTCFMSTHRIVTEGRVVTEDQLLMLEAVVMHLGIRSARCVLGMEGQQVILHLPLSQKGPFWTWEPSAPRTLLQVLQDPALKDLVLTCPTLPWHSLILRPQYEIQAIMHMRRTIVKIPSTLEVDVEDVTASSRHVHFIKPLLLSEVLAWEGPFPLSMEILEVPEGRPIFLSPWVGSLQKGQRLCVYGLASPPWRVLASSKGRKVPRHFLVSGGYQGKLRRRPREFPTAYDLLGAFQPGRPLRVVATKDCEGEREENPEFTSLAVGDRLEVLGPGQAHGAQGSDVDVLVCQRLSDQAGEDEEEECKEEAESPERVLLPFHFPGSFVEEMSDSRRYSLADLTAQFSLPCEVKVVAKDTSHPTDPLTSFLGLRLEEKITEPFLVVSLDSEPGMCFEIPPRWLDLTVVKAKGQPDLPEGSLPIATVEELTDTFYYRLRKLPACEIQAPPPRPPKNQGLSKQRRHSSEGGVKSSQVLGLQQHARLPKPKAKTLPEFIKDGSSTYSKIPAHRKGHRPAKPQRQDLDDDEHDYEEILEQFQKTI
What is the function of this protein?
May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production (PubMed:20644716).  Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity).
What are the official names of this protein?
Protein THEMIS2, Induced by contact to basement membrane 1 protein, Protein ICB-1, Thymocyte-expressed molecule involved in selection protein 2.
What is the protein family that this protein belongs to?
Belongs to the themis family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LPTD_XANOR
Sequence: MRRALRLLPLPLSIAICLPAMAADKPFNWGLCPTVDPLPGFDGAPAADPKAAEMRQQLPTDIEGDQLSGTSTTPQYQGNVALKRGDQFLGADNLRMDTETGNYIAEGNVRYQDTSFRMVADRAEGNQDTDTHKVTNIRYQLVERRGNGDAESVDLQGQVGQMHRSTYTTCDPSQPIWRVRAPEIDVDNGEGFGTARNAVLQIGNVPVLYFPWFKFPIDDRRQTGLLFPQFGLSRRNGFDYLQPIYLNLAPNYDATLLPRYMSKRGFMFGTEFRYLYEGGRGEVTGNYLPNDKLRDKDRGSVFYSGYHNVNSNWQARSSISWVSDTRYVEDFTSRLNGMGSASSLQSTVGIYGTGETWTAGLMAERWQLTDYTLDERSLPYNRQPRAYFNWEKPFGIFEAGVYAEAVRFTHDDSYFVQPPSPSVPGEANNRDNNDKYVRTNIRNQEYGSGSRLDLKPYVSMPLSGAAWFFTPTLAWRYTAYQLDSTLAKTGPLTGDRSPSRSLPIASVDAGLYFDRETSLLGTNYLNTLEPRMYYLYVPYRDQDDLPVFDTRPFTFSYGQLFRDTRYTGADRQNDANQLTLAVTSRWLRQDDGREKLSLSAGQILYFSDSRVTINNSTNAVAGSEQTIDQGKSAWVVDANYMINDRWSMGATYQWNPNSRKEDLASLRTRYLLDNDGIINLAYRYRRNLIDNSDQLKQADFSFLYPINPSWSAVGRYYYSLQDRKPLEIIGGVQWDSCCLAVRGLVRRFVRNRDGQMDNSIQIEFVLKGLSSFGQNTDRTLRRAILGYYRDDLYLVPPSNTTTNPDDYDPNLIP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.