PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_PSYIN
Sequence: MLAKRIIPCLDVKDGQVVKGVQFRNHEIVGDIVPLAKRYAEEGADELVFYDITASSDARVVDKSWVSRVAEVIDIPFCVAGGIKTIDDARRILEFGADKVSINSPALADPSLINRLSEKFGVQCIVIGIDSYFDKETGLYQVKQFTGNEKATLTTKWNTFDWIKEVQSRGAGEIVLNVMNQDGVRCGYDIDQLTQARAVCNVPLIASGGAGEMVHFAEVFKQADVDGALAASVFHKQIINIGELKAYLKTQQVEIRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_DELAS
Sequence: MALQQIVEQTVTGLGYDLVEIERSAGGLLRVTIDLPWQPPVEGGPVVPEQFVTVEDCEKITRQLQFALEVDGADYTRLEVSSPGIDRPLRHEQDFTRFVGEVIDLTLKEPIGAAAEGQVSANRKKFRGTLERAEDGGWQIVWSDEPPVKPGQKVSKKRVPAPLQALGFTLEELREARLAPIVDFKGRSAKPV
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_PSEA7
Sequence: MTADSALYIPPYKADDQDIVVELNSRFGAETFTVQPTRTGMPVLWVPRERLIEVLTFLRQVPKPYVMLYDLHGVDERLRTHRRGLPNADFSVFYHLMSLERNSDVMIKVALSERDLNLPTATRIWPNANWYEREVWDMYGITFTGHPHLTRMLMPPTWQGHPLRKDYPARATEFDPYSLSAAKQDLEQEALRFKPEDWGMKRHGENEDYMFLNLGPNHPSAHGAFRIILQLDGEEIIDCVPEIGYHHRGAEKMAERQSWHSFIPYTDRIDYLGGVMNNLPYVLSVEKLAGIKVPQRVDVIRIMMAEFFRILNHLLYLGTYIQDVGAMTPVFFTFTDRQRAYKVVEAITGFRLHPAWYRIGGVAHDLPRGWDKLVREFLDWMPKRLDEYETAALKNSILRGRTIGVAQYNTKEALEWGTTGAGLRATGCDFDLRKARPYSGYENFEFEVPLAHNGDAYDRCMVKMGEMRQSLRIIEQCLKNMPEGPYKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANEAFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSFAHLQQIPSVINGSMIADLIAYLGSIDFVMADVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NU1M_BRAVA
Sequence: MLLTNILCLMMPILLAVAFLTLTERKILGHMQLRKGPNTVGPHGLLQPVADAVKLFTKEPLHPLTSSKLMFIIAPTLAFTLALSLWAPLPMPHPLINLNLSILFILAMSSLAVHSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMLINGSFTLSTLTITQEQMWLILPTWPLAMMWFISTLAETNRTPFDLSEGESELVSGFNVEYAAGPFALFFMAEYTNIILMNALTATLFFGAFHNPLFPELHTINLTTKTLILVFLFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCTWHMTMPISLAGIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PDXH_LEGPC
Sequence: MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYTNYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPLKSQFSAIVSPQSQEILDRISLEDALNQLIEEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: Y1733_ARCFU
Sequence: MEDVVRIVVEGEKVKMWDILGDYREVRGRVVEMDLVGHKIILEGE
What are the official names of this protein?
Uncharacterized protein AF_1733.
Protein: FB121_ARATH
Sequence: MLLYFLITCLSFFFFTKSLSLPPWASETKTLLSFYFIKNPFMNTLHQTKHDPASPVIDQMSVLDLPELALDCILDLLPPSGLCSMARVCSSLRERCVSDHLWEKHLKTKWGKILGPAAHREWQCYISSSTYHLDSPHHQTGNLGFAKIISLIRSLSSVFREDKQRRGYASSLPLDSSMSCYLSLETGRFWFPAQVYNRENGHVGFMLSCYDAELSYDTHTDTFQARYPPHGRRASAIEKGVTWDRIRAAPIDASPHLLHVSDSLKELKPGDHIEIQWRRNKEFPYGWWYGLVRHLESCDGDHNHCHCHLSETVVLEFNQYTVGSRWRRTMIMRDHKEEGNEEDGFYGGIRKLNCKEEIAMWKRHWPCSILE
What are the official names of this protein?
F-box protein At2g32560.
Protein: RNY1_KLULA
Sequence: MLLNKGLLASLLAYTTTAFDLQHIFYKEQYSCPISLPASCSNNTEIKDSCCFEFPGGIMLQTQFWDYIPPKGVSDPDELVRHLGPLDSFTNHGLWPDNCDGTYAQFCNRESNIDDVWHLLNDDQFNGRDDLPINGTDLLETMDMYWKSNTGDDESLWVHEYNKHGTCIRTLYPDCYKKWGVAGNSKKQAVYDYFRIAMKLFHDKDTYQTLKSAGIEPSVEKSYTKLEISNALKEGHSGEVVHFLCDRHGSLNQIWYFHSLKGSLLGEKFVPISALPKGSNCPDDNIKWYPKGHVPSSYRPPNGNHPGTRGVVRIGNGKGFLIKNGHWYLKGTPANFFLIEAPFGNYYLKTRMGYCGIDNSNKVLACNKNVAQAAQFEYDAKKGYIGYNGAYDWYATKYPRGNQQAPVYAGSNDDGYNFQLKFVKA
What is the function of this protein?
Rnase which modulates cell survival under stress conditions.  Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death.  Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
What are the official names of this protein?
Ribonuclease T2-like, RNase T2-like.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Vacuole lumen. Cytoplasm. Note=Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress.
Protein: UVRC_CLOPE
Sequence: MFDFQHQLKILPDKPGVYIMKNSLGEVIYVGKAKVLKNRVRQYFQNSKNHSEKVRAMVKNIAEFEYIVTDSEMEALILECNLIKKYSPRYNIALKDDKFYPFIKITTNEDFPRVYVTRNFAKDGNRYFGPYTNGTAVYEVMGLIKKLFPLRTCKKAIVEGGEPTRACLNYHINLCKAPCAGYISKAEYWEMIDEIINILNGTDTSIIKKLKLEMEKAAEELEFEKAAKIRDRILAIELISEKQKMFTVKEGDEDFIDLYTDEKDGCAQVFFVREGKVTGREHFMIENIGDDPVKEVISSFIASFYGGTAQIPKTIYVPEEIEDQELIEKFLTEKRGSKVWIKVPKKGDKKNLLDMVRNNAKIMLDQFKEKMVEEKELNKSALTELADVLGLDSLPVRIEAYDISNIQGVDSVGTMVVFENGKAKNSDYRRFKIKSVKGPNDYESMREILSRRFSHGLEEVNKIKERNLEYSNGKFCIFPDLIMMDGGKGQVNIALEVLKGFGIEIPVCGLVKDHKHRTRGIILNNEEILIRRGSGLMNLITRVQDEVHRYAITYHRSLRDKRTLHSILEDIPRIGEKRRRNLLMKFGSIDNIKKASMEELLDTPGIDKRAAESIKQYFSS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_ALIF1
Sequence: MFEDIKLIAFDLDGTLLDSVPDLARAVDLAMQDMGYPRVTLEQASHWIGNGADVLVSRALSQNYIVKDDLDAELIKQARARLDQHYHDGGHQLSHLYPDVKDTLERLHQQGYTLALVTNKPSQFVPELLEQHQLTHLFSEVIGGDTFAEKKPNPFALNWLLDKHGLTAPQMLMVGDSKNDIQAAQAAGCHSFALTYGYNHGEPISDSQPDVVSDEFKYLLAVLSMAR
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: LLDD_HAEI8
Sequence: MIISSASDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFGEKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIKRPMWFQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHSGMSGPYKEIRRVLQGFTHPFWAYDVGIKGKPHTLGNVSTYMGRQIGLDDYIGWLTENFDPSISWKDLEWIREFWEGPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVLSSARALPPIADAVKGDIKIIADSGIRNGLDIVRMLALGADATMLGRAFVYALGAAGRQGVENMLDIFKKEMRVAMTLTSNRTIVDIKPEALVDLSKL
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUSB_HYDCU
Sequence: MNLSDFKPGEGTEVPEEEKSVSVRTQTRRVALQALYQWQVNHSETVDIIKQFSEEGRLVDTDVALFQEIVNEVANHAADLDELYAPFLDRAVARIDPVEKNIMRMGVFELQNKLEIPYRVVINESVELAKRFGAEDSHKYINGILDKAAEGLRSLEKTQTD
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NORR_ECO55
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMMPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYRFPGNVRELEHAIHRAVVLSRATRNGDEVILEAQHFAFPEVTLPPPEAAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGMKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: GCP1_ARTBC
Sequence: MIVKSLSLLALAAATVEGCVRERDVGSVDILSVLSKRGHGHPHLPHLSKYESMLINSFDNTTVDSWAYYYTHGIHIAGTNQSMAQWTADKWTEFGIPSSLVSYDVYLNYPVSHSLSLTHPDGTTWEASLVEDVLKEDDTTSYPDRIPTFHGYSASGEATAEYVYVGRGQKVDFERLIQLGVDLKGKIAIARYGGPFRGLKVKNAQDQGMIGCIIFTDPADDGNVTVANGLKAYPNGPARNPSAVQRGSVQFLSMFPGDPTTPGYPSRPDSPRKDKSPVVPKIPSIPISQLDAQPILAALDGHGTPGKEVNRTRWVGALNATYATGPAPGAKLSMSNVMRDTYTPIWNSIGIINGTEQDEVVIIGNHRDAWIIGGAGDPNSGSSIMVELAKAFGKLQKAGWKPKRTIVMCSWDAEEYGLVGSTEWVEEYLPWLKASAVAYLNIDVAVSGPVPDLSATPELHKLALESMKKVIWPYKGRQDTTMYDVWNTASGGEVGVLGSGSDYTAFVHNGIASLDTGAGGDGNTDPVYHYHSNYDSYHWMATYGDPGFHTHVAMGQFLGLLGYHLATDDIIPFDVTNYGVQMTKYLDVLKKYIAASKFPDLDVSKIESAICSFNVSANAVAKLQKKAEHNVHDQQLRKHLNTIYRDFGRGFVSQGGLPDREFYRHMLYAPGLDTGYAPTTFPGVTESLDAGNRTRAVEYIERASNAIYVAAGILSSCHDCNQFVAQE
What is the function of this protein?
Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity (By similarity).  Also exhibits a dipeptidyl-peptidase IV type activity (By similarity).
What are the official names of this protein?
Probable glutamate carboxypeptidase ARB_02390.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IRS1_DROSE
Sequence: MASISDDGMALSGNLKKLKTMKKKFFVLYEETSTSSARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVLQRNIANSNGTAHSPYDQVWQVVIQKKGISEKVGITGTYHCCLTSKSLTFVCIGPEKTPNGEDRVASIEILLTTIRRCGHASPQCIFYVELGRQSVLGSGDLWMETDNAAVATNMHNMILSAMSAKTESNTNLINVYQNRPDLSHEPMRKRSSSANEASKPINVNVIQNSQNSLELRSCSSPHNYGFSRERCDSLPTRNGTLSESSNQTYFGSNHGLRFNTISGIRPHSTNKHSNSPTFTMPLRCSESEDSSISVDESDDNGSFSHYRLNTRTSETAIPEENIDDFASAEFSKVTEPNESDENYIPMNPVNPTDAIHEKEKADLQRLEDASLHFNFPEHASEKLAKDFDLDSDNQCCRPIRAYSIGNKVEHLKFNKRLGHLNDTGQNPNRVRAYSVGSKSKIPRCDLQRVVLVEDNKHEFASNRSQSSIGKEGSSYGSSANRQKKSTSAPLLSLKNQINSDRMSDLMEIDFSQATNLEKQKFIKNNEIPKYIENVFPKAPRTDSSSLTLHATSQKDIFNGSKLNNTAITSEDGYLEMKPVGNGYTPSSNCLPIKVEKLKLSDYQTTAPPLLTATAAPVQDLNKISTYNISAEKWREQPSRSEEKKSNSPLNDNPFSLKPTNVESKSKSHDVHSANQIDCEKVCVQSDKLNNLTDKIVENNNLDIGGHEEKKLVHSISSEDYTQIKDKANDFTKFNEAGYKILQIKSDSSLISSKLYQKGMHKDNLERTHRLTESVNTIPDNATATVGSSSLTKFNINSVKPAADSRSTGTDPSTAQNILQIKDLNFPSRSSSRISQPELHYASLDLPHCSGQNPAKYLKRGSRESPPVSACPEDGNTYARIDFDQSDSSSSSSNIFNT
What is the function of this protein?
Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.  May mediate the control of various cellular processes by insulin-like peptides.  When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains.  Involved in control of cell proliferation, cell size, and body and organ growth throughout development.  Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions.  Insulin/insulin-like growth factor (IGF) signaling pathway has a role in regulating aging and is necessary in the ovary for vitellogenic maturation (By similarity).
What are the official names of this protein?
Insulin receptor substrate 1, Protein chico.
Protein: RL35_AYWBP
Sequence: MIKVIKKKSHSGLKKRIKITKKKKLLRGHAYKNHLAASKTTKQNRQLRGVTCVKLCDYNRIKTLIRGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RS7_HYPNA
Sequence: MSRRHSAEKREVLPDPKFKDIIVTKFMNQIMRDGKKSVAERIVYGAFDLVETRAKKNPVEVFHNALEAVAPAVEVRSRRVGGATYQVPVEVRTERRQALAIRWLAAAAAGRNENTMRERLAGELMDASQGRGNAVKKREDTHRMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS8_CAMJ8
Sequence: MINDIISDSLTRIRNAGMRKLETTKLLHSKVVEALVGIFQAKGYIESFNVIEEDKKKFINVVLKYDEKGKSVINELKRISKPGRRVYKGKDEIKRFKNGYGTIVVSTSHGVLANDEAYKAGVGGEILCTIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PAP_ENTH1
Sequence: MACELKEFLVKNDMYPMGDQVEKKRKAISKMTEYIQQWGKKIYIESAGVADDTDVKAATIYVYGSYRLNVYGNNSDIDACIVSNSTITRDDFYDGLYAELLNNPDVKELKQIPSKRSPHLSMIYLNIEFDLNFSRTAYTSLPDNLDILNENILKNMDELDTRAINGVRNTDIIDAFVPNHSEEAFRVMVRTIKLWTKKRGIYGYVYCFLNGISIEILVAQVISENYQLDNVRLLEKFFQVYSSWDWLRTPVMLGTNDDFNDKKKEGVIQILTPASPSENAAFSITKFSLEMIKRELKRGQEIVHEFSSEGVNDWAKLFKPRHLFCGYYIFIEFIVTSSSLEGLTTTIGKFESGLVNLMKGLSEIEEIIEANVIPNGFLDEENEKYFYYVGMNVKRDCPVDISTPLNSFLSIVNSGKDLIVDASIKKRSEIPTKFAHSVKRSITKSQEIKETSSQVPSSAITETFDIPTKPSIEQQLKAKEENSIPNEEKKEQLKKEMKQEANTIVKNSSTDDDFMKRFTRKN
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.  May acquire specificity through interaction with a cleavage and polyadenylation factor.
What are the official names of this protein?
Poly(A) polymerase, PAP, EhPAP, Polynucleotide adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
Protein: MURI_STRPG
Sequence: MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NAG1_YEAST
Sequence: MNSAGRVHRSRAGSRGHAAISPLTMASFSVARGIRSSNVYDDTDDELSILTFFSAVRRNRLTSSLPPILSARCSSACFSVRIVLPLSLTISISALMYSTNSALGRKLTGAFSIQTNIEQSCGFFRTSIMATLPPIECPIIIGPPLVFNSCFVIKCFTSSDMTS
What is the function of this protein?
Involved in yeast cell wall biogenesis.
What are the official names of this protein?
Protein NAG1, Nested antisense gene 1 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Localizes to the cell periphery under conditions of vegetative growth.
Protein: Y293_HAEIN
Sequence: MNISEAAKLVGLSTKQIRDYEKMGLIKPAVRSLSGYRNYGESDLERLHFIRHSRNVGFSLHQIAQLLALQDNPKRSCREVKVLTAQHIATLNQQIEQLQKMVQKLQHWHDSCQGNDNPECLILNGLNG
What is the function of this protein?
Could be a copper-dependent transcriptional activator of the ATPase HI_0290.
What are the official names of this protein?
Probable heavy metal-dependent transcriptional regulator HI_0293.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G5P_BPFD
Sequence: MIKVEIKPSQAQFTTRSGVSRQGKPYSLNEQLCYVDLGNEYPVLVKITLDEGQPAYAPGLYTVHLSSFKVGQFGSLMIDRLRLVPAK
What is the function of this protein?
Binds to DNA in a highly cooperative manner without pronounced sequence specificity.  During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form.  G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane (By similarity).
What are the official names of this protein?
DNA-Binding protein G5P, G5P, GPV, Single-stranded DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G5P protein family.
Protein: ISPD_SALPB
Sequence: MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAEAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGESGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: SMAD5_DANRE
Sequence: MTSMSSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEDLEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEVCEYPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPLNATFPESFQQHSGGSSFPISPNSPYPPSPASSGTYPNSPASSGPSSPFQLPADTPPPAYMPPDEQMGQDGSQSMETGSSLAPQNMPRGDVQPVEYQEPSHWCSIVYYELNNRVGEAYHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDTSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEVHLHGPLQWLDKVLTQMGSPLNPISSVS
What is the function of this protein?
Involved in ventralization.  May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation.  Required for initiation of Smad1 expression during gastrulation.
What are the official names of this protein?
Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, Protein somitabun, SMAD family member 5, SMAD 5, Smad5.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity).
Protein: RS8_ECO57
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SSRP_ALTMD
Sequence: MKKNKANKNTSGNIAQNKKARHDYFLEDKFEAGLELQGWEIKSIRAGKVNITDAYIIIQNAEAYLVGCRISPLNQASTHVVAAPERARKLLLKKREIDRLMGARDRQGYSIVATSMYWKKCWVKLEIHLAKGKHAHDKRDTLKDKDWQRQKERMMKHSV
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y1364_MYCA1
Sequence: MDGTDAEAPGQTAPSRAESLVAHAEASISEDALLAAARERAVDIGAGAVTPAVGALLSLLTKLSGGKAIAEVGTGAGVSGLWLLSGMSDDGVLTTIDIEPEYLRLAKQAFAEAGIGPSRTRLIGGRAQEVLTRLADESYDLVFIDADPIDQPDYVVEGVRLLRPGGVIVVHRAALGGRAGDPAARDAEVVAVREAARLIAEDERLTPALVPLGDGILAAVRD
What are the official names of this protein?
Putative O-methyltransferase MAV_1364.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: BICOA_NEIMB
Sequence: MTVLKLSHWRVLAELADGLPQHVSQLARMADMKPQQLNGFWQQMPAHIRGLLRQHDGYWRLVRPLAVFDAEGLRELGERSGFQTALKHECASSNDEILELARIAPDKAHKTICVTHLQSKGRGRQGRKWSHRLGECLMFSFGWVFDRPQYELGSLSPVAAVACRRALSRLGLDVQIKWPNDLVVGRDKLGGILIETVRTGGKTVAVVGIGINFVLPKEVENAASVQSLFQTASRRGNADAAVLLETLLVELDAVLLQYARDGFAPFVAEYQAANRDHGKAVLLLRDGETVFEGTVKGVDGQGVLHLETAEGKQTVVSGEISLRSDDRPVSVPKRRDSERFLLLDGGNSRLKWAWVENGTFATVGSAPYRDLSPLGAEWAEKADGNVRIVGCAVCGEFKKAQVQEQLARKIEWLPSSAQALGIRNHYRHPEEHGSDRWFNALGSRRFSRNACVVVSCGTAVTVDALTDDGHYLGGTIMPGFHLMKESLAVRTANLNRHAGKRYPFPTTTGNAVASGMMDAVCGSVMMMHGRLKEKTGAGKPVDVIITGGGAAKVAEALPPAFLAENTVRVADNLVIYGLLNMIAAEGREYEHI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Bifunctional enzyme BirA/CoaX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.