PharMolix/UniProtQA huggingface dataset:
Protein: Y468_MYCGE
Sequence: MFSFFKQIFKSLKKFFFLLFGIIFVLFSIIFLETSIVQLSNNLVSTYTTLVSKTNSSDIVAPAILKEANPVYIASLTNDSGYFSKIKIDDKKINYLFPYQENDFGSDSGQSNGSGDNQNKTIPRKGDVNEKDKLFLARKRGILKAYGEANIAEKRIYKGLAVSFNNTDSFNGSDISDSITNRHIISDPQNLIYDASGNLLGYFADGLIKETISLRAGIARFPGDKGKSTGTQVKITQKQQTNNDPQKDSTVNSLYKTNNKDKVWFKSDETKADNTDISANYLFTGGNEAANWFPNLYANIPIDLEIDPGSQFWKDVNPFKEIVEEFQTQKESKDNQSFTLTFNLDISKLNKLDNEQLKWLETNAKTIANNSSFGDWDLENKLKQLKKFELKINKDWLKKKVESEKDTILNSLPGFSDSDKDTIFKTQNGMMVRNNNLSFQPSSNNLQLVQNQNSQASNGIADPNFSNVQTAYNKIHQSNNTPEKTLDAVYAAVLDQWRSIFQEDLVKKTVDLLEKYRDHFLKATAFNNIDYSKQNIAIANNVSSAESASFLVSNKDEQRYNDLSLIDGVDLKSWLFKPEQNESNPLDTIYGGQDANNGFLQKIDYEFKPSTSSGGMTASLKNTQALSPKSTKFPIYPKLANIIAQAQLPEATNIPTTALDALKQWTNLDANGFNNLKEEDKRKAANNYLALLSYFTPAFQDPNELIETNRQMLEIPITVKNGVNPLILPTDQQNLVVQTPEAHGAVVSQQWLFRHNKEILPQEGEYAWKTALQTPNNFPNWLNDLPDRYKFSINGLTFAILGIGESVETGYPVLSLQSPLPNTQDEALIFVNDQAYRSILFAVPAANQENYYAFKSTDLKQHTDQDPVQFIANRLEGYLDVPRSDLAFNVKDISKFNYLTTARNYFPDLVQSYLAIVSTVIAIFLIILALYLIILLIKSFIKKNQTEFSIIRAGGFSTTKFIVGMSVFAGIVAIVSSFLGVLFAFLLEGQVKGIINRYWFIALPENSFNWLSFFGSFFITFFVFEFISWIAFKQLFSKPVNVLIDQGNETKFSVLLHLLKHKSHTMSPLTKFRVSLIVSRFSRLFTYVGLSSVALLLIGIAGTIPQKFSAAQTSTSLNRNFNYKLNLQTPTEQSGWYAIQPYSHFGVTDNNNGIKTLYNESVQANSQNEHPYKPSNLKLKNRQDQPIKAADGTELELGNLLLPSYGGAQQLNTDENFFRHASLSKWIIDFPIRVGGSNINPWEIVEKSIPKQITQLLSASSDQFLISVLTDDFFNNLNANGFLIRNPRTNQIQLDASRVLTTIDVFNPGGVKFNDSFLSFMLKVYGDFELAKQDSKLNFGIVPVDPAIEETYTYVEGPFGFQEDNLDENSPYTLTGINPESSFVNLIDGSGNSLRNLISSDQEMNVIVNAGFQYANNINIGDYVYIKPKNTATRYSEKFLKAPLNNSTVAFKVVGVSTDAFGQELYINQHIANNLLKLSGNQGRGIIRDVIKKTNGQSQSSDEYEIDYVKPNGYVPFNGVFSKELKPSLLNKALVLNSIIGVWGNFTDFGNNFQNLVRNKLDKVITSILPTDPEIINKLAQEKQIINTTSMNYESLRKELVNKYKTEWNSVNLLSQNASSIFGNNIIAPVLNIDAAGTSAQIIRNNAEVLFNTVNQVDAFLLGTIIPFIFITCVVLGISMLEEMKRIFISLKAIGYRDVQNLISLLTFFIPAFVLALLISIGVLAGVLIGIQAVVFNVAQVFLTNVFEFLPYMVGIVLFGVTIFVIGSYFWIKLRSAELKEGF
What are the official names of this protein?
Uncharacterized ABC transporter permease MG468.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRPH2_CHICK
Sequence: MALLKVKFNQKKRVKLAQGLWLMNWFSVFAGIIVFSMGLFLKIELRKRSEVMDNSESHFVPNSLILMGILSCAFNGFAGKICYDSLDPAKFAKWKPLLKPYLALCFFFNILLFFVALICFLMRGSLESTLAQGLKNSMKFYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFKDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQVTNNSAHYSYDYQTEELNLWGRGCREALLHYYSSMMSSMGAVVLLVWLFEMSVMVGLRLLHTSLESIANPEDPECESEGWILENSLKDTLKSALESLKKIGKFNQVEAGAEGAEGEEAGKTPAITTVS
What is the function of this protein?
May be involved in the morphogenesis of retina outer segment disks and the development and maintenance of the retina ultrastructure.
What are the official names of this protein?
Peripherin-2, CRDS1, Photoreceptor outer segment membrane glycoprotein 1, Retinal degeneration slow protein.
What is the protein family that this protein belongs to?
Belongs to the PRPH2/ROM1 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: MURG_BIFLS
Sequence: MDQGTPHIVLAGGGTAGHVNPLLAVAGAIRDIEPTAQVTVIGTAVGLEKDLVPEAGYELDTIEKVPFPRRPDLYMLRFPAKWKRETAKVRSILETRHADVVAGFGGYASAPVYATAHKMGIPIAIHEQNARAGMANKLGARWADFIGTVYEGTGLKPRAGADVERVGLPLRPAIASLTKRIGDDRAAVRRESAAQLGVDPNRPLVLVTGGSLGAQSLNRAIASSAADLLAHAQIIHLTGRGKISEVRELVTASAGADVLTGIGPESAGQGDYHTAEYLERIDMAFACADLVICRAGAGSVSELAALGLPAIYVPLPIGNGEQRFNAEPVVNAGGGLLVADKDLTPQWVHEHVPDLLADHERLAEFGRKAWEYGIRNAAEIMARHVLQLAEPSK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BGLS_SCHPO
Sequence: MMEHDVEDLINQLDISEKAMLLSGTDLWHTAAIPRLNIPSIRLSDGPNGIRGTSFFNSSPSACFPCGTALGATFDKKLLFEVGEYLAEEAKAKGVSVVLGPTVNIHRGPLNGRGFESFSEDSTLSGLAASYVILGLQSKNVQACIKHFVCNDMEDERNSVSIDVSQRALREVYLMPFQLACKYSNFKSLMTSYNKVNGEHVSQSRILLDNILRKEWEWKGTIISDWFGTYSLKKAIDAGLDLEMPGKPRFRNVNTIQHLVGSKELSESILDERAKNVLKLVKHSWQNTEAENHCELNNDSSCLREALKKFASQSIVLLKNKKKLLPLSRKGTFAVIGPNAKVCNYSGGGSANLKPYYTVSMYDGIAAKIDGVPEYALGCHNYLNLPNIANLLVNPRTGKHGYVAKFYLEPATSENRTLIDDYDLEDGVVRFYDYCNDKMKDGYFYIDIEGYLIPDEDAVYEFGISVFGTALLFIDDVLLIDNKTKQTPTNHTFEFGTIEERNSIYLKKGRKYNVRVEYGSAATYTLSTNLSPSTGGRYSIGCVKVIDPETEIDYAVRVAKSVDCVILCVGLTAEWETEGEDRKTMTLPSLSDKLVYSILQSNPNTVVVTQSGTPIEMPWISEAHTLLHIWYNGNELGNALANIIFGEQNPCGKLPITFPKKLKDNPAYLSFRSSRGHCVYGEDVFVGYKYYEAVEREVLFPFGYGLSYTTFELSNLYLKNCGERLRIDLEISNTGPMSGAEIIQVYISQIVRSVNRPVKELKEFSKVVLCPKETKLIRIELDIKYATSFYDELNEKWCSEEGEYNVLVGTSSKDIALTGKFTLPKTIHWTGL
What are the official names of this protein?
Putative beta-glucosidase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX1_ANDAU
Sequence: MNYLVMISLALLLMIGVESKRDGYIVYPNNCVYHCVPPCDGLCKKNGGSSGSCSFLVPSGLACWCKDLPDNVPIKDTSRKCTR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  Is active against mammals and binds with high affinity rat brain synaptosomes.
What are the official names of this protein?
Neurotoxin-1'', AaH I'', AaHI'', Neurotoxin I''.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_RHORT
Sequence: MADWYRLAWPLICGLDPERAHHLAIRALALGLAGHDRAADDPVLACSLWGRRFANPLGLAAGFDKNGEVADALFDLGFGFVEVGTVTPRPQAGNPRPRLFRLTQDRAVINRMGFNNQGMEAMAARFVRARPRGVLGINLGKNKTTEDAAGDYEAGIAKLAPLADYLVINVSSPNTPGLRALQGREPLSLLIARARAALDAACPGLRPPLLLKVAPDLTDEDMADIAEVALGGGLDGLICTNTTIARPKSLVSDHAGETGGLSGLPLRYRARQVIARLYGLTKGALPLIGVGGIGDGAEAYARIRAGASLIQIYSALVYEGPGLVGRIKRDLAQRLRADGFASVAEAVGADHRDPKGASGKLAPRSPL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYRM_PONAB
Sequence: MACGFRRAIACQLSRVLNLPPENLITSISAVPISQKEEVADFQLSVDSLLEKDNDHSRPDIQVQAKRLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVIRINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADDKSVAKAAQEFFQRLELGDVQALSLWQKFRDLSIEEYIRVYKRLGVYFDEYSGESFYREKSQEVLKLLESKGLLLRTIKGTAVVDLSGNGDPSSICTVMRSDGTSLYATRDLAAAIDRMDKYNFDTMIYVTDKGQKKHFQQVFQMLKIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIQLRMLQNMASIKTTKELKNPQETAERVGLAALIIQDFKGLLLSDYKFSWDRVFQSRGDTGVFLQYTHARLHSLEETFGCGYLNDFNTACLQEPQSVSILQHLLRFDEVLYKSSQDFQPRHIVSYLLTLSHLAAVAHKTLQIKDSPPEVAGARLHLFKAVRSVLANGMKLLGITPVCRM
What are the official names of this protein?
Probable arginine--tRNA ligase, mitochondrial, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYV_CHLMU
Sequence: MNEDQFPKAYDPKSSESGVYSFWERSGMFIADANSKKPAYSIVMPPPNVTGILHMGHALVNTLQDMLIRYKRMKGFEVCWVPGTDHAGIATQTVVERHLRSSLGKRRTDFSREEFLKHVWEWKEKSQNVILSQLRQLGCSCDWSRQRFTMDPEANRAVKKAFKVLFDKGVIYRGYYLVNWDPILQTALADDEVEYEEREGWLYYIRYPVVNSEEFITVATTRPETLLGDTAIAVSPEDERYSHLIGAKVIVPFVDREIPIIGDFSVDASFGTGAVKITPAHDKDDYRTGMNHRLPMINILTPTGEINENGGIFTGLAKESARENIITSLEALGLFVRKEAYSSRVGVSYRSGAIIEPYLSKQWFVSVDSFRESLREFVNSKEINLFPPEFIRNYLTWVNNLKDWCISRQLWWGHRIPVWHNKHDEEYVICFDGDGVPEEVAQDPESWYQDPDVLDTWFSSGLWPLTCFGWPEESADLRKFYPTSVLVTGHDILFFWVTRMVLMCSAMVDTKPFADVFLHGLIFGKSYKQYDDNGEWTYVSGDQKREYDKGKALPKNVVAKWEKLSKSKGNVIDPIEMIDMYGADAVRFTLCSCANRGEQIDLDYRLFEEYKNFVNKLWNGARFIFGHISELTSRDLEEGVNKDLLGLEDFYILDRFNELLALIDSHYNCYSFDKIAALAYDFFKNDLCSTYLEIIKPTLFGKQGNDEQRATKRKLLATLLVNILGVLHPIVPYITETLFQKIKTTLGVVGDGLGDAVTGHAVSMLRSEACMIAGYPQPIELSFPQGLRESFAIAEKLVYTIRNIRGEMQLDPRDLLQAFIISSEKKELLDACIPIMCALGGIKTIEQLSEAPKDCIFSLGVVEGIQVGVILPAEHLAKEHARLEKEKIRLENSIESLSKLLASEDFRTRANPNLVQAKEDALRNSRQELQSILDKIASL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_PSET1
Sequence: MVIKCAFKECRPYLNELETRFGLAHWADQSSGFSLHYDDTGLSLYKTDEPKLGAISVDFVTGAAAHRRKFGGGKGQAIAKAVGLNKGATPIVLDATAGLGRDGFVLASLGCKVILHERHPVVAALLYDGLQRAYNDIEIGPWMQQNMSLIFGSSHTLLAQCESMPDVVYLDPMFPHREKSALVKKEMRVFQDLVGADTDADDLLEFAYPLASKRVVVKRPDYAPFLNDKTPSMQIKTKKNRFDVYVKAAMKK
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M4A8_HUMAN
Sequence: MNSMTSAVPVANSVLVVAPHNGYPVTPGIMSHVPLYPNSQPQVHLVPGNPPSLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATVLVGEYLSISFYGGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHPYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNIYAANPVITPEPVTSPPSYSSEIQANK
What is the function of this protein?
May be involved in signal transduction as a component of a multimeric receptor complex.
What are the official names of this protein?
Membrane-spanning 4-domains subfamily A member 8, Four-span transmembrane protein 4, Membrane-spanning 4-domains subfamily A member 8B.
What is the protein family that this protein belongs to?
Belongs to the MS4A family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TAL_MYCLB
Sequence: MTSKIQNPNLAALSAAGVSVWLDDLSRDRLQSGNLQKLIDTKSVVGVTTNPSIFQKAFANGHAYDAQIAELAKRGANVDVTVRTVTTDDVRHACDVLACEWEASHGKDGRVSIEVDPRLAHDTDKTIAQAVELWRIVDHPNLFIKIPATKAGLPAITAVLAEGISVNVTLIFSVQRHREVIDAYLAGIEKAAEAGRDLSKIVSVASFFVSRVDTEIDKRLEKLGSEQALALRGQAGVANARLAYAAYQKAFEGGQRYQTLMARGAQVQRPLWASTGVKNPDYADTLYVTELVAPNTVNTMPETTIDAVADHGVIRGDTISGTTLSSQKVFDSLVAVGVDLIDVFAVLEHEGVQKFVKSWNELLKETQEQLDSVAK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_VIBVU
Sequence: MQELRFVLIVVGALAIMALLFHGLWTSKKEGKAKFGDKPLSKLDLGESEPKESEMYVAPEDDYEIIRKERKEPAFEDEKPFSTSGVIGDPLIDDLHSGQDKENKFSQPKFDDDITVAEAEAAASIEQDAPAWVEQPQEIDEPLTHHPDEIDAFSGEETIVELDEPMSQTVEPELQVIVLNVHCAGDSPFVGTKLFDSMQQNGLVYGEMDIFHRHLDMSGTGKVLFSVANMMHPGTLKHDDPAEFSTKGISFFMTLPCYGEADQNFNLMLKTAQKIADDLGGNVLDDKRNLMTPDRLAGYRRQIVEFKAANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: GPDA_CORU7
Sequence: MVQVAVMGAGSWGTTVAKVFADSGNPVTLWARRDEVADDVNDNHRNSAYLGDVDLPEGLSATTDPAAALHGAEIVVLGVPSQTLRSNLSSWREHIEPNATIISLAKGIEYETGMRMSQVIADVAGVGSDRVAVLTGPNLAKEVAQGQPAATLIACEDDERARFVQSAVAAPYFRPYTSQDVLGAEVAGTSKNVIALAAGIAAGCGFGANTNATVITRGLAETTRLALQLGADARTMAGLAGMGDLVATCTSPLSRNRSFGQRLGEGAGLEAAAEATKGQVAEGVVSCRSVQALARKAGVEMPITDAVVQVCYEDASPKEIINQLLGRTRKPE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_NITMU
Sequence: MVKAATRVRKKVKKNVAEGIAHVHASFNNTIVTITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAEQAGRAAQEYGVKNLEVRIKGPGPGRESAVRALNAAGFKITSISDVTPVPHNGCRPPKKRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: IRS4_MOUSE
Sequence: MASCSFSGHQALRRLRASAAAAASAALAAVATTPLLSSGTRTALIGTGSSCPGAMWLSTATGSRSDSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYRNARKFRHSVRAAAAAAEAAASGAAVPALIPPRRVIILYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGALPDGEPAALAAAAAAEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSTRRHLGLLPLEPGGWLRRYGLEQFCRLRAIREREEMLFTRRFISPREPPPPFRRGRGHLPRARRSRRAASVPPSLFRRSAPSPGRIPQPEDVPNDRAREASGSSSGNTEEKDKEGEEGNRGDCIPMNNWGSGNGRGSGGGRGSSGQGSSSQGSGGRQGSGGGQGSGGQGAGGNQCSGNGQGTAGGHGSGGGGHGSGGGQRPGDGHGSGGGKNSGSGKNSDDGDRGKSVKKRSYFGKFTQSKQQQTLPPPPPPPPAAGATGGKGKSGGRFRLYFCADRGTKERKEAKEVRDMETSGGATRGPYRARAFDEDEDDPYVPMRPGVAAPLACSSDYMPMAPQNSSASTKRHSRSPFEDSRGYMMMFPRVSPPPPVPSAPKAPDTNKGDDSKDNDSDSDYMFMAPGAGAIPKNPPNAQGGSSSKSWSSYFSLPSPFQSSPLGQSDHSEYVPMLPGKFLGSGLHKEASFSQGTKNVSSKPSTEASFSKPEDKGSSAKPSDDVPPMNKAKEPNHLSFIAKGTQVKPKPLNPTQERREAAGSRDYINIDFIKRERLVLPSSAQGLPDMRGVVTDPAPTAFSGYLNVEFGVPFPNPTIRLSDLLRVLPGANSIPLAGTRWPFPGSAIGSIVEAGEYIEVIFNPAMTPAMSFADSAICYDAQTGQIYVVDPFSECCMDVSLSPGRCSEPPPVARLRREEAQERRRPQSRSQSLFASTRAAVSAFPTDSLDRDFPAASAVIAAPAEAPLLAVSRALAVVSALAAAPSIGDVFAGFRAAAGVDSASARGFQPVAGAQAVREFQDLAAGWNPGALNHRARGEDLAAGAAAPPPPPRQIWVLRPQERADSEDDDDDDDDIYVRMDFARRDYRK
What is the function of this protein?
Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains.  Involved in the IGF1R mitogenic signaling pathway.  Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis.  Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity.  May be involved in nonreceptor tyrosine kinase signaling in myoblasts.  Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation.  May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis.  Plays a role in growth, reproduction and glucose homeostasis.  May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2.
What are the official names of this protein?
Insulin receptor substrate 4, IRS-4, Phosphoprotein of 160 kDa, pp160.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COG8_DROME
Sequence: MDFPDKMDLENERVLKLIFPDGVPDNLRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAISNYRTFITTAENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLNSITLQKNAQLLEVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVEALWHNMLVQLVAQLRTDLQLPKCLQIVGYLRRMQAFGDNELRLKFLQARDAWLTSCLEAIPTADAQQHLSKTIEITRINLFNIITQYRAIFPEDEGTLKTQSSLRPLQGVSCNGDRLFQAWLHNKISDFLQTLERDLQLGVGSVETVLGQCMYFGLSFSRVGADFRALMAPIFVGVIRRRFESSVEQVDEQFERELERFTLINKVALHSHARKQVDPEQESYAPPEALLDFYPLAALCNGYLSALNELRLCAPLALATDVTRCLQHSLQQAAQRVLAFYRQEQQAFAGSEREAFVRLCSCLAYDLVPYIQRCIHGVFPPQSLTVHLGISLLQLEQQQLTYLQQTRILEPLKHLLPTKALVQPQDKVMEAKPSAGVPVTAEG
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 8, COG complex subunit 8, Component of oligomeric Golgi complex 8.
What is the protein family that this protein belongs to?
Belongs to the COG8 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: PLSY_HELPJ
Sequence: MEGVLNFLTNINVIFTLLGYLIGGIPFGYALMKIFYGMDITKIGSGGIGATNVLRALQSKGVSNAKQMALLVLILDLFKGMFAVFLSKLFGLDYSLQWMVAIASILGHCYSPFLNFNGGKGVSTIMGSVVLLIPIESLIGLTVWFFVGKVLKISSLASILGVGTATVLIFFVPYMHIPDSVNILKEVGTQTPMVLIFIFTLIKHAGNIFNLLTGKEKKVL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSRP_BORPA
Sequence: MTSTPIERAVYIVSDSTGITAETFSHSVLSQFDEVNFKPVRLPFIDTLDKAREVVARINRNALEAGVPPIVFSTLVNPEILALVRQSNGVFLDLFGTFVSHIEQALGLKSSHSIGRSHMAANSEKYRNRIDAINFSLAHDDGQFVNQLDQADVILVGVSRCGKTPTSLYLAMQYAVKAANFPLTPDDFERGALPKTIAPYRGKLFGLSIQPERLAEVRNERRPNSHYARLEQCRYEVAEAERMMRREGISWLSTTTKSIEEIATTVLQEVGLERV
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: ETIF1_ANOGA
Sequence: MSIQNLNTFDPFADAIKGADYDVQDGLVHIRIQQRNGRKTLTTVQGLSAEYDLKKIVRACKKEFACNGTVIEHPEYGEVLQLQGDQRENICQWLTKSGLAKPEQLKVHGF
What is the function of this protein?
Probably involved in translation.
What are the official names of this protein?
Eukaryotic translation initiation factor eIF1, Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: MUTL_STRPB
Sequence: MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKYMKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLVISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAVDNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RL21_XANOR
Sequence: MYAVLVTGGKQYRVAQGETLRVEKLEVEAGNEIKFDTVLMLGDSDGIKLGDALKGASVTAKVVAHGRADKVRIIKFRRRKHHMKRQGHRQHYTEIEITGIAGGDKK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NUDC_PECCP
Sequence: MEQTLKGDETGWWVVSDAVQIWLPQGELPCGTATKWSLQGKTARQIGEWQEQPVWLVCQGRDTDMASVRQLLDQDVGLFQLAGRGVQLAEFYRSHRFCGYCGHEMVRSKTELACLCHHCKERYYPQIAPCIIVAIRRGEEILLAQHNRHRGNMYTVLAGFVEVGETLEQTVVREVMEESQVQIKNLRYVSSQPWPFPHSLMMAFMAEYAGGEIKHDPKELRDAGWFRYDQLPQLPPPGTVARRLIEDTVVLCRAYHENEG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: S20AB_DANRE
Sequence: MVSTTLATITIMSTLVGYTTGPLTDYMWLLIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETLGSVLLGAKVSETIRKGIIDVTMYKDIEHVLMAGSVSAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSLVAKGQQGVKWLELLRIVASWFLSPLLSGVMSAVLFYFVRMFILQKKDPVPNGLRALPFFYAVTMGINLFSIMFTGAPMLGFDKLPWWGVLLISIGFGIITALIVWFAVCPRLKKKIECEVKSSSPSESPLMEKRELHEAHSPILKPVPEESSVLSSSTPTTPPLPPPEERRVTFDIGDSDDADQKDCKESDLGGAPKTAHVHFTNGPAHIPSNGYSQYHTVHKDSGLYKDLLHKLHLAKVGDCMGEGGDRPIRRNNSYTSYTMAIIGMHGDFKPKESEFRASEDGDKEKAGAQERKRIRMDSYTSYCNAVAENGTPEDLGEGEVTLEMVDEDAGSSRSSLEEDRTDADKPEVSMLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLVYESGSVISSAPTPIWLLLYGGVGICVGLWVWGRRVIQTMGRDLTPITPSSGFSIELASAVTVVVASNIGLPVSTTHCKVGSVVAVGWLRSRKAVDWRLFRNIFMAWFVTVPISGLISAAIMALFNYVIL
What is the function of this protein?
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.
What are the official names of this protein?
Sodium-dependent phosphate transporter 1-B, Solute carrier family 20 member 1-B.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KDSA_KLEP3
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFIEGGNDKVILCDRGANFGYDNLVVDMLGFGVMKKASNNSPVIFDVTHALQCRDPFGAASGGRRAQVSELARAGMAVGIAGLFIEAHPDPDHAKCDGPSALPLDKLEPFLKQMKAIDDLVKSFDELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.