PharMolix/UniProtQA huggingface dataset:
Protein: MSCL_RALSO
Sequence: MALMQDFKKFAMRGNVIDLAVGVIIGAAFGKIVDSLVNDLIMPLVARIVGKLDFSNLFIQLADAPAGVPQTLADLKKAGVPVFAYGNFITVAVNFLILAFIVFLMVRAITRVIDTNPPPADTPENTLLLRDIRDSLKSKNQ
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_VIBVU
Sequence: MKAQDLREKSVEELNSELLNLLREQFNLRMQAATGQLQQTHTLKAVRRDIARVKTVLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYGA_RICFE
Sequence: MKKLSFQQIILALQNYWQDYGCAILQPYDAHVGAGTFHPATVLRCLGSKPWSVAYVQPSRRPGDSRYGMHPNRMQHYYQFQVILKPSPDNIQELYLKSLECLGIDLKKHDIRFVEDDWESPTLGAAGLGWEVWCNGMEVSQFTYMQQIGGIECRPVAGEITYGLERLALYIQGVDEVKELDWNGQIGEKALKYGEVDFEAERQFSKYNLELANSKMLLRHFKDSEEECKRLVDGDVPLAAYDECLKASHTFNQLNALGVISVTERASYILRVRHLAKICCMKWLELSGE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BACC7
Sequence: MQKVTIQEAEHLLQEIMSEEDDRFQILMKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVVLPKDFYIPGLNDSKKLSEAKRERFYDEIKAQAIAIGVGIVSPQVIDEINIYQATKQAMLDAVANLSCTPQYLLIDAMKLPTPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGILEEHRKSFAPIKDMIQK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_VIBPA
Sequence: MSITNEQILDAVAEMSVMQVVELIEAMEEKFGVSAAAAVVAGGAAAGAAVEEQTEFDVILESAGGNKVAVIKAVRGATGLGLKEAKALVDGAPAPLKEGVDKAEADALKAQLEEAGATVAVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RPOB_BARHE
Sequence: MAQTLAMTSQFNGRKRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMIEEPKGGRPDEGLQAVFKSVFPISDFSGTAMLEFVGYQFDSPKFDVEECRQRDLTYAAPLKVILRLIVFDVDEDTGSKDIKDIKEQGVYMGDMPLMTTNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKFLFAARVIPYRGSWLDIEFDAKDIIYARIDRRRKIPVTSLLMALGMDASDILSTFYNKVTYERDGDGWRIPYSVDRFKGMKLVSDLIDADSGEVVAEAGKKLTVRAAKALAEKGLKAVKVSEDDLLGSYLAEDIVNYQTGEIYLEAGDEIDEKTLRVLFDVNADQIDILDIDHMNIGAYIRNTLKVDKNESRQDALFDIYRVMRPGEPPTMDTAEAMFHSLFFDPERYDLSAVGRVKMNLRMDLDCPDTVRVLRQEDILAVVKMLVELRDGRGEIDDIDNLGNRRVRSVGELMENQYRIGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIIDGKVTTEVIYLSAMEESKHYVAQANSSLDAEGRLSEEFVVCRHAGEVLMAPRDHVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMESIVARDSGAAVAARRSGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQSTCINQRPLVHVGDRVEKGNIIADGPSTDLGDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVAEEALRNLDEAGIIYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGAFGTVVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQSILDRNVYARLTDMLVGKVAVEGPKGFSKNKKLDTTIMGHYPRSQWWQFTVEDEKLQNEIEALRNQYDESKEALQRRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRILPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWACAGMGKKIGDLVDLYQETGDILPLRQRIENLMPDDDHNEPVRQYDNESLYKLALQMRKGVSIATPVFDGAHEADINMMLEDAGLDSSGQVTLYDGRTGEPFDRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLALNVELDDARELIAQRALSDTTEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL13_SPICI
Sequence: MRQTTILNSTKVEKKWYVIDAQGLVLGRLASKVAMILRGKNKPSYTPHVDCGDNVIILNADKINLSGNKLKGKMYYHHSQHPGGLKRTTAKNMLVKKPIYPVEHAIKGMLPKNKLGSKLFRNLFVYAGNEHPHEAQQPIKLELTNK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y1273_CAUVN
Sequence: MVATLFIDADACPVKDEAYKVAARHGYKTFVVSNSWIRVPATPVIEQIVVDAGPDVADDWIAERCGPGDVVVTNDIPLADRVLKAGGAAVAPNGRVFSHDMIGSALASRSIGEHLRSMGEVTKGPAAFANADRSRFLQALDQLVVKAKRAAPR
What are the official names of this protein?
UPF0178 protein CCNA_01273.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: Y2262_ARATH
Sequence: MVLETPVCSPIDKESSSDDVQLNKPPKKKRKLDVVYPPRDNTSSSSDVKPKVPGYCGVKAIGCNRSDELLAEVALHSYNSQTGTNLELMTVTQVMLQSVAHINYHMILDAFDPANNSLSSIEICLWDAAVKNNEKLRLVTTFCSLEGSGDKGSQWDPNGVDVLYTGVMPKWLDDGALSGSEKLHYYEVNDSDLQENKWLHLYAQVGAYSKWDLGMVKHFPLEIKKVVVQTMEDDIESNLKLKSSNAIFYITFTTSGGVECACIIRQTRNGRPQHMCLEINNVEMDK
What are the official names of this protein?
UPF0725 protein At2g20620.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: QCR7_YEAST
Sequence: MPQSFTSIARIGDYILKSPVLSKLCVPVANQFINLAGYKKLGLKFDDLIAEENPIMQTALRRLPEDESYARAYRIIRAHQTELTHHLLPRNEWIKAQEDVPYLLPYILEAEAAAKEKDELDNIEVSK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 7, mitochondrial, Complex III subunit 7, Complex III subunit VII, Ubiquinol-cytochrome c oxidoreductase subunit 7, Ubiquinol-cytochrome c reductase 14 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRB/QCR7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYR_RIPO1
Sequence: MTSINEQLTNYFIQALVKAFGAEFSDIDPIVVPASNPKFGDYQANIALSLAKKLGEQPRAIAQKIIDNLSLEDLGELPTIAGPGFINIKIKPTYLATQLKVQQNSSSLGVTKADPIEKIIVDFSSPNIAKEMHVGHLRSTIIGDCIARILEVRGHQVLRLNHVGDWGTQFGMLIAYLAEVYPDALTTADALDIGDLVTFYKQAKKRFDEDEKFQETARNQVVKLQAGDSQTRHAWQLLCEQSRREFQVIYDILDINITERGESFYNPLLEDIIKELDHQGLLKKDAGAQCVFLDGFTNKSGDPLPLIVQKSDGGYNYATTDLAALKYRITQDQAERIIYVTDAGQANHFAQVFQVAKKAHIIPKNVEIIHVPFGLVKGEDGKKLKTRSGTTIKLRDLLDEAVIYARQDLEKRLAEEGRQESEDFIANVSQVVGISAVKYADLSQNRTSDYIFSYDKMLALQGNTAPYMLYAYARIQSISREGNIDFESLQQEAKIILQEETEIELGKYLLQLSEVIEEVEKTLLPNRLCDYLYELSKKFNRFYENCPVLKSEEPLRTSRLLLCDLTARTLKLGLSLLGIPVLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLD4_MOUSE
Sequence: MASMGLQVLGISLAVLGWLGIILSCALPMWRVTAFIGSNIVTAQTSWEGLWMNCVVQSTGQMQCKMYDSMLALPQDLQAARALMVISIIVGALGMLLSVVGGKCTNCMEDETVKAKIMITAGAVFIVASMLIMVPVSWTAHNVIRDFYNPMVASGQKREMGASLYVGWAASGLLLLGGGLLCCSCPPRSNDKPYSAKYSAARSVPASNYV
What is the function of this protein?
Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney (PubMed:20921420).  Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts (PubMed:20921420).  Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-4, Clostridium perfringens enterotoxin receptor, CPE-R, CPE-receptor.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=CLDN4 is required for tight junction localization in the kidney (PubMed:20921420, PubMed:25831548).
Protein: RN185_CHICK
Sequence: MASKGPTTSASTKSSSTGGTSGSSSSNGAGDNTNQDNTFECNICLDTAKDAVISLCGHLFCWPCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENRGGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAVPGTPQYVDEQFLSRLFLFVALVIMFWLLIA
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination.  Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation.  Protects cells from ER stress-induced apoptosis.  Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway.  Also acts as a regulator of the innate antiviral response by catalyzing 'Lys-27'-linked polyubiquitination of CGAS, thereby promoting CGAS cyclic GMP-AMP synthase activity.  Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF185, RING finger protein 185.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ARGB_PSEU2
Sequence: MTLERDAASNVAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKTGFARDIVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFIDGMRVTDAQTMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRAKKLTVTRQTPEMTKPEIIDIGQVGEVVGVNTGLLNMLVKGDFIPVIAPIGVGPDGESYNINADLVAGKVAEALKAEKLILLTNIAGLMNKQGEVLTGLTTEQVDGLIADGTIYGGMLPKIRCALEAVQGGVNSSHIIDGRVPNAVLLEIFTDSGVGTQITNRKRH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7A_STAMF
Sequence: MSKPFYVKFEVPPELAEKVYEAVKKARETGGKIKKGTNETTKAVERGIAKLVIIAEDVDPPEIVAHLPLLCDEKKIPYVYVPSKKRLGEAAGIEVAAASAAIIDPGGAKDLVEEIIKQVQELRAKAGA
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_ACIBT
Sequence: MKSYHPKSLLNDLQYYITPPHDCSYLENKSARMVFLDPIHRIDVVTLSELSRLGFRRSGDFVYRPECHLCRQCLSCRVPVADFQMNSMQKKAWKRNQDLTMTVLPTRQASQIHYDLYERYINERHADGDMFPPSLDQFEKFLVHSCTDSFFLELWKDNRLISVSTCDLMDDGLSAVYTFFDPDEHRRSLGVYSILNQIEYVKTLGLEYVYLGYWVPHSAKMNYKSQYTPLELLLDGQWRRLNRSLSPEEINQLGNSLMTTLPSEWNNLIIK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEQA_SHEHH
Sequence: MKYIEVDEELYRHIASKTEHIGESASDILRRILGLQVESVVQDAPEEISHPSLERVSPKPVKVAKVITKMTSTAVSDFTSLIDADVLAAQKGAVGRFLFILDTVHRASPVQFEQVLQIQGRDRLYFATSKDALLKASKSANPKEIGQSGFWVTTNNNTAKKRTILSEVLLQFGTDEAQVTDIIEKI
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPVL_STAAM
Sequence: MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
What are the official names of this protein?
Putative dipeptidase SAV1751.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: MENG_BACFR
Sequence: MNYPQEKIKPYSNDGKKSEQVEQMFDNIAPAYDQLNHTLSLGIDRSWRRKAINWLKPFRPQQIMDVATGTGDFAILACHELQPEQLIGTDISEGMMNVGREKVKKEGLSEKISFAREDCTSLSFADNRFDAITVAFGIRNFEDLDKGLSEMYRVLKTGGHLVILELTTPDRFPMKQMFTIYSKIVIPTLGKLLSKDNSAYSYLPQTIKAFPQGEVMKNVISRVGFSQVQFRRLTFGICTLYTATK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: IF1_CLAMS
Sequence: MAKKDGVIEIEGGVVEALPNAMFRVELSNGHKVLAHISGKMRQHYIRILPEDRVIVELSPYDLTRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_PHOPR
Sequence: MTNAFFLTGTDTEVGKTVASRAILHAAASANIKMAGYKPVASDSTPTDEGMRNSDALYIQDASVVELDYQEVNPYAFEAAISPHLAAEQEGQVIDFDVLSAGLEHLKSKSEAVLIEGAGGWRVPISHTDFLSSWVKREKLPVILVVGVKLGCLSHAILTAEAIKNDGLELVGWVANRINPGTENYADIIKMLEKNLPGKKMGEIPYMPALKNVTYQSILI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MREB_HAEIN
Sequence: MLFKKIRGLFSNDLSIDLGTANTLIYVKRQGIVLDEPSVVAIRQDRVGTLKSIAAVGKEAKLMLGRTPKSIVAIRPMKDGVIADFFVTEKMLQYFIKQVHSGNFMRPSPRVLVCVPAGATQVERRAIKESAIGAGAREVYLIEEPMAAAIGAKLPVSTAVGSMVIDIGGGTTEVAVISLNGIVYSSSVRIGGDRFDEAIISYVRRTFGSVIGEPTAERIKQEIGSAYIQEGDEIKEMEVHGHNLAEGAPRSFTLTSRDVLEAIQQPLNGIVAAVRTALEECQPEHAADIFERGMVLTGGGALLRNIDILLSKESGVPVIIAEDPLTCVARGGGEALEMIDMHGGDIFSDEI
What is the function of this protein?
Forms membrane-associated dynamic filaments that are essential for cell shape determination.  Acts by regulating cell wall synthesis and cell elongation, and thus cell shape.  A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
What are the official names of this protein?
Cell shape-determining protein MreB.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane-associated.
Protein: RL10_PHYAS
Sequence: MIKPQLAKKIETVSFLQEKISQAKTVIVFEYSNLPVSEFMKLRRQLKKIDCEVKVYPKNIMQRAFMNTNYQDLVSLLKGIKALIISQQELLEPIKVIYNFAKQNKVVKIVSGVVEQKIVSPQEINSLATLPSKEQMLALLSVAMLSPLRQLAFALKLLSEKQATNN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CAPSD_HCYV5
Sequence: MPFSRRRRVVRRRKPVRRLRRRRRRFFKRAGRGSFRVKLTRFVSITQDISKTTQFSFEITPSDFTEFATLADAFEAVRFTRAKVTVLPQQNVSNNSTSLIPAYCMFPWHKELPTVATFNGFLSIDRAKCFRGTQVGIQHYVPSTLDSIQTKGAAGYEVQSVQTKYKPTIQISGGASTVVLYTGALGMQALSDAPENAQAHYNIKIDMWCTFINQTSFNK
What is the function of this protein?
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry.  This very small capsid (17-22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents.  Essential for the initial attachment to heparan sulfate moieties and chondroitin sulfate B of the host cell surface proteoglycans.  After attachment, the virus is endocytosed and traffics to the nucleus.  The capsid protein binds and transports the viral genome and Rep across the nuclear envelope.
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the circoviridae capsid protein family.
What are the subcellular locations of this protein?
Host nucleus. Virion.
Protein: EX7S_ACIC1
Sequence: MTEPPLPHESADDGRARLSYEDARDELIQIVQRLELGGLPLEEALRLWERGEELARVCQAWLDGARARLEAYRAPEQSAANDVSAPGSAEEHDHGR
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7195_ESCCA
Sequence: MEESLWVVTATVVVVFAIAKLLKKSSSISTMEWPKGPKKLPIIGNLHQLGGEAFHVVLANLAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNISCSDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKPLDYLKEETIRLLSRLIFGQSFNDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVNERVVNLVKPYLVKNPPTNTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTASTAVWALTFLVREPRVQEKLYKEIIDLTGGERSVKVEDVSKLPYLQAVMKETMRMKPIAPMAIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQGQESKYGDIKEMEQSLLPFSAGMRICAGMELGKLQYGFSLASLVEAFKWTCAVDGKLPDLSEDHCFILLMKNPLEARITPRTQL
What is the function of this protein?
Methylenedioxy bridge-forming cytochrome P450 involved in the biosynthesis of isoquinoline alkaloids.  Converts (S)-scoulerine into (R,S)-cheilanthifoline.  Catalyzes an oxidative reaction that does not incorporate oxygen into the product.
What are the official names of this protein?
Cheilanthifoline synthase, CHS, Cytochrome P450 719A5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ANFC_ANGJA
Sequence: MMCKALVFAVLLLAVPLERADSRALRTPVDAIQFVEQFLEHYNDLLNIDDLENQTGDQLESPQPLSSGLKVAEYPKWVDVPSQNDNTWFRLLRGALANRKRALPDRAKRGWNRGCFGLKLDRIGSLSGLGC
What is the function of this protein?
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation.  May also be vasoactive and natriuretic.  May be important for freshwater adaptation.
What are the official names of this protein?
C-type natriuretic peptide, BNP-like peptide CNP-22.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: CADH1_XENLA
Sequence: MGLKRPWLLGAVVLLTLIQVQGGLAEWTQCRMGFSKEKYSFLVPKNLETDKALGRVIFNSCEGPVRIQFASKDPNFEIHKDGTVYIKNPAKMKDNRKTFRVLAWETKGHVYSTNITLKREGHRHRQDLFSGKHSHHPKSETGLKRQKRDWVIPPIIVSENEKGPFPKRIVQIKSSYAKEVKVYYSITGQGADTPPEGVFAIGREDGWLNVTRPLDREAIDNYVLFSHAVSSNGANVEDPMEIIIKVQDQNDNDPVFTQSVFEGSVPEGSKPGTAVMTVSATDADDSVDMYNGVITYSILNQEPKEPTNKMFTIHSESGLISVLTTGLDREKNPVYTLTIQAADGEFGKDRTTTATALIVVMDTNDNPPVFDPTQYTAKVPENEVGYEVARLTVTDEDIEGTDAWNAVYKIIKGNEANYFSIQTDTGNIGLLKTVKGLDYELKKQYILSVIVTNKANFSVPLQTSTATVTVSVEDVNEAPIFLPPVKEVSVSEDLPSGQVVATYTAQDPDKEQNQKITYVIGNDPAGWVSVNKDNGIVTGNGNLDRESKFVLNNTYKVIILAADSGSPSATGTGTLVLNLLDVNDNGPFLEPQQESFCQKDPGFRVFTIIDRDLSPNTYPYKAELTGESNENWTAIVTGQSILELRPKKELEIGQYDVMITLLDSFGLSNVTKLHITICQCDGDKMQCEEKAAIAGGLGISAIVGILGGILALLLLLLLLLLFVRRKKVVKEPLLPPEDETRDNVFSYDEEGGGEEDQDFDLSQLHRGLDARPDVIRNDVAPVLAAPQYRPRPANPDEIGNFIDENLNAADNDPTAPPYDSLLVFDYEGSGSEAASLSSLNSPNSDLDQDYSALNDWGPRFTKLADMYGGDED
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  E-cadherin is a ligand for integrin alpha-E/beta-7.
What are the official names of this protein?
Cadherin-1, Epithelial cadherin, E-cadherin, Uvomorulin, xTCAD-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PGSA_TREPA
Sequence: MRLSDFYTALRLALVLPFFALYHMSRWVVMYFPAANVGRVVSIASVLLFLFIACTDFLDGYYARKSGKYSSFGKVFDPFADVIANVTVMLCLVADNFMPVFLFLCILYREFGMMFLRMLACGEGHVVGAQRMGKLKTASYMGAVLFSLLLKALYAFELAGADWYERMRAVGRLVYVVPVVLALASFFSYLKTFFPILKRVCGRTRYPVCKTCREWD
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.