PharMolix/UniProtQA huggingface dataset:
Protein: EFG_ROSCS
Sequence: MPREVPLERIRNIGIIAHIDAGKTTTTERILFYTGRTYKLGEVHEGTAVMDWMEQERERGITITAAATTAEWTVEGTPYRINIIDTPGHVDFTAEVERSLRVLDGGVVVFDAVAGVEPQSETVWRQADKYHVPRICFVNKMDRIGANFMRTVDMIRERLGAKPVPVQFPIGAEDRFRGIVDLITNKAVIYVDDQGKREELEAIPADVADEVERLRNEMIEAIAETDDELTLLYLEGEELSVEELRRALRKATIQGKLVPVLCGAALRNKGVQRLLDAVVYYLPSPVDIPPVRGTRPGQIAGDDGVEMITRPTSEDAPFTGLVFKIVSDPFVGKLAYFRVYSGKLETGSYVLNSTRNQRERIGRLLQMHANHREEIKEVYAGDIAAMVGPKQSYTGDTICDPNDPIVLESIRFPEPVIQLAIEPKTKADQDKLAVALGKLAEEDPTFRVFTDPETGQTIIAGMGELHLEVIVDRMRREYKVEANQGKPQVAYRESITVPADVDSKFVRQSGGKGQYGHVKLQVEPLERGKGFEFVNGIVGGVIPREYIPAVEAGVKEAMASGVIAGYPVVDIKVTLYDGSYHEVDSSEMAFKIAASMGLKEAVRKGRPILLEPVMKVEIVTPEDFLGAVLGDINSRRGHVEGMEARGNAQVIRAYVPLASMFGYTTDLRSATQGRATSSMEFAYYQPLPDALAKEIIEKRRG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UQCC2_HUMAN
Sequence: MAASRYRRFLKLCEEWPVDETKRGRDLGAYLRQRVAQAFREGENTQVAEPEACDQMYESLARLHSNYYKHKYPRPRDTSFSGLSLEEYKLILSTDTLEELKEIDKGMWKKLQEKFAPKGPEEDHKA
What is the function of this protein?
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).  Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells.  Involved in cytochrome b translation and/or stability.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 2, Breast cancer-associated protein SGA-81M, Mitochondrial nucleoid factor 1, Mitochondrial protein M19.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion inner membrane. Note=Predominantly expressed in the mitochondrial inner membrane.
Protein: UVRB_CAMJE
Sequence: MLELTSEFKPSPDQQEAIKGIVKSIKKGNKYQTLLGVTGSGKTFTMANVIKELNIPTLIMSHNKSLCAQLYSEFKGFFSKNHVEYFISYYDYYQPEAYIPRTDVFIEKDSSTNEDLERLRLSATASLLSYEDVVCIASVSANYGLGNPNEYIGMVLIFELGMQISQKELLKKLVDMGYKRNDNFFDRADFRVQGDIIDIYPAYYEDEVVRLEFFGDELDAMYHYNVLENKKGKDLKRFILYPTSQFSVGETRLKQAIKDIKAELNERLAYFEHENKLVEYQRLKQRVEFDLEMLTSTGMCKGVENYARHLTGLKEGDTPYTLFDYFAIKDRKFLVIVDESHVSLPQFRGMFAGDRSRKQTLVDYGFRLPSALDNRPLMFDEFIHKNCQFLFVSATPAPLELELSKENIFHQIMRPTGLLDPLIELKDSDNQVEILFDEAKKVIQRNERVLVTVLTKKLAEELTRYYLELGIKVKYMHSDIDAIERNEIIRGLRSGAFDMLIGINLLREGLDLPEVSLIAIMDADKEGFLRSTTSLIQTMGRAARNVNGKVLLFCKKITKSMQEAMDTTNERRKLQMAYNKKYNITPTSVKRHIEESLKNEEDLGEIYRKGKKLEKMPASERAKLVKELRKQMLEAAKALEFEKAAAIRDEINKLRDL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_ALIF1
Sequence: MQVSDFHFELPDELIARYPQPERTASRLLQLNGNSGELNDGQFTDILDLVQAGDLLVFNNTRVIPARMFGMKASGGKLEVLVERVLDEHSVLAHVRCSKSPKPGTMLLLGENQEHEAEMVARHDTLFEIRFTSDKKVLDILDEIGHMPLPPYIDRPDEDADKERYQTVYNKKPGAVAAPTAGLHFDTEILEKMKAKGVEFAYVTLHVGAGTFQPVRVDNILEHHMHSEYAEVSQEVIDAINATKARGGRVVSVGTTSVRSLESAAQHALKQGTELAPFFDDTEIFIYPGYEFQVVDALVTNFHLPESTLIMLVSAFAGYENTMKAYEQAVNNKYRFFSYGDAMFITKKTA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCO1_HUMAN
Sequence: MAMLVLVPGRVMRPLGGQLWRFLPRGLEFWGPAEGTARVLLRQFCARQAEAWRASGRPGYCLGTRPLSTARPPPPWSQKGPGDSTRPSKPGPVSWKSLAITFAIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLGGPFSLTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKKS
What is the function of this protein?
Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2).  Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation.  Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (PubMed:15659396, PubMed:16735468, PubMed:17189203, PubMed:19336478, PubMed:15229189).  Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity).
What are the official names of this protein?
Protein SCO1 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LLP_BPT5
Sequence: MKKLFLAMAVVLLSACSTFGPKDIKCEAYYMQDHVKYKANVFDRKGDMFLVSPIMAYGSFWAPVSYFTEGNTCEGVF
What is the function of this protein?
Inhibits of the adsorption of T5 to its FhuA receptor.  By this means, T5 within cells excludes superinfection by T5 and other phages using FhuA receptor as a ligand.
What are the official names of this protein?
Lytic conversion lipoprotein.
What are the subcellular locations of this protein?
Host cell outer membrane; Lipid-anchor. Note=Attached to the host membrane by a lipid anchor.
Protein: EFP_BORA1
Sequence: MKTAQELRVGNVVMVGKDPLVVQKTEYNKSGRNAAVVKLKFKNLLTGSASESVYKADEKFDIVMLERKECTYSYFGDPMYVFMDADYNQYEIEADSMGDALNYLEEAMPVEVVFYDGRAISVELPTILVREITYTEPAVRGDTSGKVLKPAKINTGYELQVPLFCAIGDKIEIDTRTNEYRSRVN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_TRIEI
Sequence: MSSHQKLYEGKAKILYTTDDPEILLTYFKDDATAFNAQKKGTITGKGKINCTISSHIFKLLETNEIPTHFIDCPASDKMRVRRVKILPIEVIVRNIAAGSLCRQTLLTEGTILKFPLVEYCYKNDTLQDPLLTRDRLLILELATPEQLEQIRTFAVKINDILINFFNQCQITLVDFKIEFGLDKHENLILADEISPDSCRLWDQYQTDPNQRVMDKDRFRRDLGKVETGYQQVLERILAHQG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: KDSA_POLSJ
Sequence: MKLCGFDIGLNQPFFLIAGPCVVESEQLQMDTAGTLKEITSSLGIPFIFKSSYDKANRSSGTSFRGPGMVKGLEILAKVKRELNLPLLTDVHSEADIATVASVVDVLQTPAFLCRQTDFIHAVAQSGKPVNIKKGQFLAPGDMKNVIDKARAAAREKGLNEDNFMACERGASFGYNNLVSDMRSLAIMRETNAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETHPDPAKALSDGPNAVPLKHMKALLETLLELDRVTKKNGYLENSFGA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DP13A_MOUSE
Sequence: MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPISQFKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNGQLEEFLANIGTSVQNVRREMDGDVETMQQTIEDLEVASDPLYLPDPDPTKFPINRNLTRKAGYLNARNKTGLVSSTWDRQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESKKDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPGGQSRPPTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCEDQPGQAKAFGQGGRRTNPFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIFRMTESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSGGRSESNLSSVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELSKQKQIEKDLEEQSRLIAASSRPNQAGSEGQLVLSSSQSEESDLGEEGKKRESEA
What is the function of this protein?
Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism (By similarity) (PubMed:25328665, PubMed:25568335, PubMed:27219021).  Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex (By similarity).  Functions as a positive regulator of innate immune response via activation of AKT1 signaling pathway by forming a complex with APPL1 and PIK3R1 (PubMed:25328665).  Inhibits Fc-gamma receptor-mediated phagocytosis through PI3K/Akt signaling in macrophages (PubMed:25568335).  Regulates TLR4 signaling in activated macrophages (PubMed:27219021).  Involved in trafficking of the TGFBR1 from the endosomes to the nucleus via microtubules in a TRAF6-dependent manner.  Plays a role in cell metabolism by regulating adiponecting and insulin signaling pathways (By similarity).  Required for fibroblast migration through HGF cell signaling (PubMed:26445298).  Positive regulator of beta-catenin/TCF-dependent transcription through direct interaction with RUVBL2/reptin resulting in the relief of RUVBL2-mediated repression of beta-catenin/TCF target genes by modulating the interactions within the beta-catenin-reptin-HDAC complex (By similarity).
What are the official names of this protein?
DCC-interacting protein 13-alpha, Dip13-alpha, Adapter protein containing PH domain, PTB domain and leucine zipper motif 1.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Nucleus. Cytoplasm. Endosome. Cell projection, ruffle. Cytoplasmic vesicle, phagosome. Note=Early endosomal membrane- bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
Protein: BRLA_ASPOR
Sequence: MRTQNNLTVEVDCHSLGSNECPSMTSSFSPMDSPTPTPTSIYSQGSLASPGWQDAGSYPGHAYERHTGATPMRSAFRLAGMTSNENMGMSYGAMEAQERMPMPDFLSAYDDNVEHFWLPSDGPKTYETGTHSLPYPHTLPQCPPMVRSNYRPHAAYLPEAATNPCLSRSIFHHAERVPQSMSMGNMMPWIPQATESIAPQTIAPSQVGPVTPPPSYSEFPTSIQTFKTHSPTTPLRSCSIGTASGPDTPISRLSGGAADYLEDFQQSPPFRDGLNRLQRQPSRKMIRKQSSRQNMSLENLPSIIKQVQFKCKEPGCKGRFKRQEHLKRHMKSHSKEKPHVCWVPGCERAFSRSDNLNAHYTKTHSKRGGRNRYVATLDESSPDYDPDFRGQLTPDGLPIRGSTLDDPMPNSREYSVDGLDD
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity).  Required for conidiophores formation (PubMed:17213655).  Controls expression of abaA (PubMed:19850144).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development brlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_MAGSA
Sequence: MPKRILQGVVVSDKMEKTVVVSVERRVMHPIYKKFIRRSKKYHAHDENNVFKTGETIRIRECAPISKTKCWEVIVEPQA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RF1_RHIWR
Sequence: MAGITSARIAQIEARRDELQALMARGDLPSDQFVQLSKDYAEIEPVAQAAGEVRRLRAELDVLKGMAEDEAGDAELRAMAIEEAEEIRARLPEAERALALKLLPRDAADERSAMLEIRAGTGGDEAALFAGDLFRMYQRYAEDRGWRVELISASAADLGGYKEVVASVTGAGVFARLKFESGVHRVQRVPVTESGGRIHTSAATVAVLPEAEEVDVHIDDKDLRIDVYRSSGPGGQSVNTTDSAVRITHLPTGLVVIQQDEKSQHKNKAKALKVLRTRLYEMERERLASERAGARKSMVGSGDRSERIRTYNFPQGRVTDHRINLTLHRLSEILEGPGLDDLVGALIAEDEAERLAQLDG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTSO_DAUCA
Sequence: MSTSIFETPLPRSDLFLCSNSLLSQNYKLFDNSRSFGLKSLRPRCQKDGLLYPKPLNFGFCRVSRRKRKPNFVLNSVLSVDKELESDETVGLGRSREYDAIVIGSGIGGLVAATQLAVKGAKVLVLEKYLIPGGSSGYYERDGFTFDVGSSVMFGFSDKGNLNLITQALAAVGCKMEVIPDPSTVHFHLPSNLSVLVHREYNEFFSELTSKFPHEKEGIFKFYGECWKIFNALNSLELKSLEEPIYLFGQFFKKPMECLTLAYYLPQNAGDIARKFIKDPEVLSFIDAECFIVSTVNALKTPMINASMVLCDRHYGGINYPVGGVGGIAKSLAKGLVDQGSEIQYKANVKSIIVENGKAVGVRLANGNEIFAKNIISNATRWDTFGKLLKQDELPKEEENFQKLYIKAPSFLSIHLGVKSDVLPPDTDCHHFVLEDDWSNLEVPYGSIFLSIPTVLDSSLAPEGNHILHIFTTSSIEDWQGMSQKDYEKKKELVADEIISRLEKKLFPGLQSSIVLKEVGTPKTHRRYLARDSGTYGPMPQGTPKGLLGMPFNTTAIDGLYCVGDSCFPGQGVIAVAFSGVMCAHRVAADLGLEQKSPILDAALLRLLGWFRTLA
What is the function of this protein?
Carotene cis-trans-isomerase that converts 7,9,9'-tri-cis-neurosporene to 9'-cis-neurosporene and 7,9,9',7'-tetra-cis-lycopene (also known as prolycopene) into all-trans-lycopene.  Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds.  Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis-double bonds at C9 and C9' (By similarity).
What are the official names of this protein?
Prolycopene isomerase, chloroplastic, CrtISO, Carotenoid isomerase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein.
Protein: THIC_PELTS
Sequence: MNYATQMEAARKGIITREMETVARKEMVDPAKLRELIAEGRVVIPANKNHASLDPCGIGQGLRTKINVNLGVSRDCCNIGMELEKARLAIELKADAIMDLSCYGRTEEFRRRLIEMSPAAVGTVPVYDAVGFYGKELKEISAEEFLGVVEKHAQDGVDFMTIHAGINRETAARFKKNPRLTNIVSRGGSLLFAWMELNGRENPFYEYFDELLEICRKYDVTISLGDACRPGSVKDATDASQIQELIVLGELTKRAWEKDVQVMIEGPGHMPLNEIIPNMLLEKKLCHGAPFYVLGPLVTDVAPGYDHITSAIGGAIAAASGADFLCYVTPAEHLRLPTLEDMKEGIIASRIAAHAADIAKGVPGARQWDDKMSEARRNLDWQKMFELALDPEKARRYRAESQPESEDTCTMCGKMCAVRNMNRVLSGAGPDG
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: IDD14_ARATH
Sequence: MIDYERSNTTKNINTHHHNPPPSSSSSDLLPDGNGTAVTQKRKRRPAGTPDPEAEVVSLSPRTLLESDRYVCEICNQGFQRDQNLQMHRRRHKVPWKLLKRETNEEVRKRVYVCPEPTCLHHNPCHALGDLVGIKKHFRRKHSNHKQWICERCSKGYAVQSDYKAHLKTCGTRGHSCDCGRVFSRVESFIEHQDTCTVRRSQPSNHRLHEQQQHTTNATQTASTAENNENGDLSIGPILPGHPLQRRQSPPSEQQPSTLLYPFVTNGSIELQLLPSRNCADETSLSLSIGTMDQKTMSEVEKKSYEKGETSLEREEARRETKRQIEIAELEFAEAKRIRQHARAELHKAHLFREEASRRISATMMQITCHNCKQHFQAPAALVPPPPQTHCTDESTSLAVSYMSSATTEGEKASDRASS
What is the function of this protein?
Transcription factor regulating starch metabolism by binding directly to the promoter of QQS (PubMed:21556057).  The IDD14beta isoform attenuates the transcription factor activity by competitively forming heterodimers with reduced DNA-binding capacity(PubMed:21556057).  Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602).  Has a redundant role with IDD16 in directing leaf and floral organ morphogenesis (PubMed:24039602).  Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602).
What are the official names of this protein?
Protein indeterminate-domain 14, AtIDD14, Transcriptional regulator of starch metabolism IDD14.
Protein: RETM_ANOGA
Sequence: MVQKYESPVRIYKYPFELVVAGFRNFCRQKSVLRRGKVCEMGSIFGEAKTTTNTWCIRRWSFAVVCKKIIIEEFLFLFVKHQLYQYLCNHIVNIEYAYHKPYNSFATRVEIFEKCRYYAHPENPDWTCFDQTATLDIKNFFGIEHSMEKMGMKQYTQTTLKGKEIIEFFVNELKQEGITHVDRWVDDATVTSTTAGAATNTTPPEKPPLCRDNSILDADYIAKYLGQLTPLQESKLVQLRKRFEHGTSEHPEPDYQTLLRFLRARDFSIDKATGMLQESLQWRKEQRIDSILGEYKTPAVVEKYFPGGWHHHDKDGRPLYILRLGTMDVKGLLKSVGEDELLKLTLHICEEGLRLMKEATKLFGKPVWNWCLLVDLDGLSMRHLWRPGVKALLRIIETVETNYPETMGRVLIVRAPRVFPVLWTIVSTFIDENTRSKFLFFGGPDCMHAEDGIEQYIDTDKIPSFLGGSCNVIDCPIVALPNSVCVNRPVSSSSFDSSIVKLSPPPALSPHAFCSVATAIAYSLHFATLNGGIAHDHHGLYKAVDLKPGQLFELLIRNTDPKSVLTWDFEVLKNDTLFAVFHTEKEIEQSGNDDFSSVFDGPDFKEGTNYKKIEQSVKCRPKEGVQGSHEMASTGTYVLQWMCPPSCDGPAQLMYFHEILSSANYKGSMTSLQSGFSSNSLQSR
What are the official names of this protein?
Protein real-time.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CC122_HUMAN
Sequence: MSDNKERKSQGFPKEDNQDTSSLADAVEKVAKQQQSQASEIEKNKKVLFNLKNELHELEKEIAAISAETKETERQIYQQDSAIENTKLHCDSLETQIKSLHSENVKLKFDIETAQEDFEEHMIKYNAYYAKIKAHKNSLGEVESKWSFMTELHEKRDFVKKLKTMKEELMQDLQNPGGNRITQVQEDITNLKDKIITVKESIIEKTCFLEEEKKTHEKLRKEIEVQHKRYDAILKRLHCQVNKLQSNRRQWQWNIQQLEKTAAELRKCIGMQE
What are the official names of this protein?
Coiled-coil domain-containing protein 122.
Protein: NADA1_METAC
Sequence: MQQADLIKRIQELKVKRNAVILSHYYSRPEVQDIADFVGDSLALSQEAVRQDADVIVFCGVHFMGESAAILSPKKTVLLPEIDSTCPMADMVDVEGLKRLKEKHPEAPVVSYVNSSAAIKAESYICCTSANAVEVVNSLDVDEVIFVPDKNLAAYVASRTDKKIIPWEGHCPTHHQILREDVLKMKEKHPLAKFIAHPECRPDVLELADHVASTRGMIMYAKNSPAREFIIGTECGLIHGLHKAAPEKTYYCISEFACCPSMKMVNLEKLLASLEKMQHVVTVPEEVRVRAKEALDRMLAVKVK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_STAAW
Sequence: MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SYY_AGRFC
Sequence: MSRFKSDFLRTLDERGFIHQISDEAGLDELFAKETVTAYIGYDPTASSLHVGHLTQIMMLHWMQKTGHQPISLMGGGTGMVGDPSFKEEARKLMTIDMIEDNITSLKHVFANYLDYDRAENPALMINNADWLRGLNYLEFLRDVGRHFSVNRMLSFDSVKTRLDREQSLSFLEFNYMILQAYDFVELNQRTGCRLQMGGSDQWGNIINGIDLGHRMGTPQLYALTSPLLTTSSGAKMGKSASGAVWLNKDLLPVYDFWQYWRNTEDADVVRFAKLFTTLPMDEIARIATLGGSEINEAKKILATEVTAILHGRAAAEEAAETARKTFEEGALAENLPSIEVPTSELDAGVGVLSLIVRAGLASSNGEARRHVQGGAVKINEQGVSDERQIIGTGEVTGDGVIKLSVGKKKHVLVRPA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDM2_HUMAN
Sequence: MNQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFVGDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINRAIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRKGKKKSQENKNKGNKIQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDCSEVTPAMQIPRTKEEANGDVFETFMFPCQHCERKFTTKQGLERHMHIHISTVNHAFKCKYCGKAFGTQINRRRHERRHEAGLKRKPSQTLQPSEDLADGKASGENVASKDDSSPPSLGPDCLIMNSEKASQDTINSSVVEENGEVKELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGGLEEPQPPAEQAQATQNVYVPSTEPEEEGEADDVYIMDISSNISENLNYYIDGKIQTNNNTSNCDVIEMESASADLYGINCLLTPVTVEITQNIKTTQVPVTEDLPKEPLGSTNSEAKKRRTASPPALPKIKAETDSDPMVPSCSLSLPLSISTTEAVSFHKEKSVYLSSKLKQLLQTQDKLTPAGISATEIAKLGPVCVSAPASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGKPSDGKAAWTDAGLTSKKSKLESHSDSPAWSLSGRDERETVSPPCFDEYKMSKEWTASSAFSSVCNQQPLDLSSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQETFNKNFVCNVCESPFLSIKDLTKHLSIHAEEWPFKCEFCVQLFKDKTDLSEHRFLLHGVGNIFVCSVCKKEFAFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKAHVEHMQSLPEDPLETSKEEEELNDSSEELYTTIKIMASGIKTKDPDVRLGLNQHYPSFKPPPFQYHHRNPMGIGVTATNFTTHNIPQTFTTAIRCTKCGKGVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPKNGVVVLDNSGKNAFRRMGQPKRLNFSVELSKMSSNKLKLNALKKKNQLVQKAILQKNKSAKQKADLKNACESSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHSSPASSDKNSNSNHRRRTADAEIKMQSMQTPLGKTRARSSGPTQVPLPSSSFRSKQNVKFAASVKSKKPSSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKAVLQSKSTLASKKRTDRFNIKSRERSGGPVTRSLQLAAAADLSENKREDGSAKQELKDFSYSLRLASRCSPPAAPYITRQYRKVKAPAAAQFQGPFFKE
What is the function of this protein?
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3.  May function as a DNA-binding transcription factor.  Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
What are the official names of this protein?
PR domain zinc finger protein 2, GATA-3-binding protein G3B, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain-containing protein 2, Retinoblastoma protein-interacting zinc finger protein, Zinc finger protein RIZ.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.