PharMolix/UniProtQA huggingface dataset:
Protein: FOG2_MOUSE
Sequence: MSRRKQSKPRQIKRPLEDAIDDEEEECPVEEAEVISKGDFPLEGSFPAGFEPENLSCEDVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGELEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNSLKTKAQVPMVLTAGPKWLLDVTWQGVEDSKNNCIVYSKGGQLWCTTTKAISEGEELVAFVVDFDSRLQAASHMTLTEGMYPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREAAPVSEENEDNSHQVSSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKCTVCSYTADSVINFHQHLFSHLTQAAFRCNHCHFGFQTQRELLQHQELHVPSGKLPRESDMEHSPSGTEDSLQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLTNQRPEIQPAANKQNFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFAFPQDITMVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPLMPKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSEKMPEAVSPNTGQTSINLLNPAAHSSDPENPLLQTSCINSSTVLDLIGPNGKGHEKDFSTQVKKLPTSNSSDDKINGKPVDVKNPSGPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLAMNKCVPVPKCDTTHSNVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHECTVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERSSPEVSFERNMIKCEKNGNPKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAIKKTKGADQLSPYYGIKPSDYIASSLVIHNTDVEQSTNTENESPKGQASSNGCAVPKKDSLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNTQHEDGHKSPSWISENPLAANENVSPGIPCAEEQLSSIAKGVNGASQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK
What is the function of this protein?
Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis.  Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6.  Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context.  Also required in gonadal differentiation, possibly be regulating expression of SRY.  Probably acts a corepressor of NR2F2.
What are the official names of this protein?
Zinc finger protein ZFPM2, Friend of GATA protein 2, FOG-2, Friend of GATA 2, mFOG-2, Zinc finger protein multitype 2.
What is the protein family that this protein belongs to?
Belongs to the FOG (Friend of GATA) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_RHOP5
Sequence: MRCPSCSSLDTQVKDSRPTEDSSVIRRRRVCLACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVDPERLEEMVSAVVRELESGGESEISSEAIGEIVMEHLRKLDDVAYVRFASVYRNFREAKDFEAVLGELSSDELARAALLRK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DEFI6_MOUSE
Sequence: MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLNIPHDPVALEEHFRDDDDGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADGIGSSPLSNQDAFRLWCLFNFLSEDKYPLIMVPDEVEYLLKKLLGSLSLEMGLGELEELLAQDAQSAQTAVGLSVWQFLELFNSGRCLRGVGRDSLSMAIQEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSSLCYFGSEECKEKRGTIPLDAHCCVEVLPDREGKRCMFCVKTASRTYEMSASDTRQRQEWTAAIQTAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHKELQQALEGQLREAEQARASMQAEMELKKEEAARQRQRIAELEEMQERLQEALQLEVKARRDEEAVRLAQTRLLEEEEEKLKQLMHLKEEQERYIERAQQEKQELQQEMALQSRSLQHAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPTTSSSFTGFQPPPLARRDSSLKRLTRWGSQGNRTLSVNSSEQKSLNGGDETPILALASQEEKLDPAPGN
What is the function of this protein?
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42 (PubMed:12648457, PubMed:12923183).  Can regulate cell morphology in cooperation with activated RAC1 (PubMed:12648457, PubMed:12923183).  Involved in immune homeostasis by ensuring proper trafficking and availability of T-cell regulator CTLA-4 at T-cell surface (By similarity).  Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling.  Required for optimal T-cell effector function, lymphocyte homeostasis and the prevention of systemic autoimmunity (By similarity).
What are the official names of this protein?
Differentially expressed in FDCP 6, DEF-6, IRF4-binding protein, SWAP-70-like adapter of T-cells.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, filopodium. Note=Recruited to the plasma membrane upon binding phosphatidylinositol 3,4,5-trisphosphate. Binds to actin filaments.
Protein: ISCU_BUCBP
Sequence: MAYSKKVIDHYENPRNVGSFKTIDANVGSGLVGAPACGDVMKLQIKVNKNGIIQDACFKTYGCGSAIASSSLVTEWIKGKSLIEAENIKNTNIAEELDLPPVKIHCSILAEDAIKAAITDYKNKNK
What is the function of this protein?
A scaffold on which IscS assembles Fe-S clusters.  Subsequently gives the nascent cluster to other proteins.  It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly scaffold protein IscU, Sulfur acceptor protein IscU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: TOP3A_DROME
Sequence: MKAVLTCFRPVVASHRRYCANPGQAMKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFDFEAPVRGQNAKMVMTSVSGHMMQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGYEIIDVCRAIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITRFQTMRLQRLFPEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKIKVLHTIDDLTVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVEMEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQTGHRDWGAFAQRVIEWGPNPRNGNKSDQAHPPIHPTKLAENLQGNEARVYELVVRHFLACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKWSAKQIHHYENGQRFEPTEVSLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYIGVLDKGFLVPGVIGMGLYEGYDAMELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQQITDKITAMDAKISARINETPAANSAVQEGADGSAPSHGIIQSIFQCPKCNEAPLALKPKKNQQGWYIGCNNFPDCKNAVWLPTECKDASVLDECCPTCGDGYRMLKFRLSTPYYRGVFGTPSGWYKTCLPCDNLFRTTFNINLDSVKKVGGIVGEVRGGGGGPGPGPGGGGSGRGAGSGGWSSGPGGGGSGGGGGSGGWGSGTGGGGSGGWGSGTGGGGLGGGKGKKPGGESKKSATKKPPNEPKPKKTKEPKAAPNKKTSSKSSGSIRSFFTSAAPTNSASNGLDEFFDSNDGFEDAMLAAAESVESSSQPKTISMVPLDDDIAAAFAADDDAEFEALVNGGTMPTESNGDQQLDKSLSEWIKEQDKADERPMLWGTRERASLGTAAPTPPPKPAAKRPRWDSVERDSTPPSSVPESETVLCTGCQQPARQNTVRKNGPNLGRLYYKCPKPDECNFFQWADEPPSSAKSKNSTGSAPQSTTSWGSNRVVTLPSIQQSNSQRGQSSMRSNSSSTVTITQTKTKQQERNTATPGDGEEVMCNCGQLASQLTVRKDGPNQGRPFYACPTREKSCGFFKWGDEDQNQGASSTSWGSANRNPPGRSQPTAITSDGPKTRRCGLCRKEGHTRNKCPRKDEFDM
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).  Weakly relaxes negative supercoils and displays a distinct preference for binding single-stranded DNA.
What are the official names of this protein?
DNA topoisomerase 3-alpha, DNA topoisomerase III alpha.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: RL11_COXBR
Sequence: MAKKITGYIRLQIKAGEANPSPPVGPALGQHGVNIREFCESFNTATKNIEKGLPTPVIITVYADRTFSFITKTPPASVLLKKFVLKGKSGSARPNTEKVGKATRQQLEEIAKMKTPDLTAADLEAAIRTIAGTARSMGIDVEGVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HIS7_METAC
Sequence: MRTGRISRKTKETDIQLELNLDGKGVADISTGLGFFDHMLASFSRHSEFDLKVRAEGDLYVDEHHLVEDVGIVLGRALAEVLGDMSGIARFGEARIPMDEALAEVALDVGGRNYLVLKAEFASPQVGQFSTQLVRHFFETLASNAKITMHASVYGDNDHHKIEALFKAFAYAMKRAVKIEGKEVKSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRL37_ARATH
Sequence: MNCCWQVVEPCYKSALSYLCVKVGNICMLKENLVLLKSAFDELKAEKEDVVNRVNAGELKGGQRLAIVATWLSQVEIIEENTKQLMDVASARDASSQNASAVRRRLSTSGCWFSTCNLGEKVFKKLTEVKSLSGKDFQEVTEQPPPPVVEVRLCQQTVGLDTTLEKTWESLRKDENRMLGIFGMGGVGKTTLLTLINNKFVEVSDDYDVVIWVESSKDADVGKIQDAIGERLHICDNNWSTYSRGKKASEISRVLRDMKPRFVLLLDDLWEDVSLTAIGIPVLGKKYKVVFTTRSKDVCSVMRANEDIEVQCLSENDAWDLFDMKVHCDGLNEISDIAKKIVAKCCGLPLALEVIRKTMASKSTVIQWRRALDTLESYRSEMKGTEKGIFQVLKLSYDYLKTKNAKCFLYCALFPKAYYIKQDELVEYWIGEGFIDEKDGRERAKDRGYEIIDNLVGAGLLLESNKKVYMHDMIRDMALWIVSEFRDGERYVVKTDAGLSQLPDVTDWTTVTKMSLFNNEIKNIPDDPEFPDQTNLVTLFLQNNRLVDIVGKFFLVMSTLVVLDLSWNFQITELPKGISALVSLRLLNLSGTSIKHLPEGLGVLSKLIHLNLESTSNLRSVGLISELQKLQVLRFYGSAAALDCCLLKILEQLKGLQLLTVTVNNDSVLEEFLGSTRLAGMTQGIYLEGLKVSFAAIGTLSSLHKLEMVNCDITESGTEWEGKRRDQYSPSTSSSEITPSNPWFKDLSAVVINSCIHLKDLTWLMYAANLESLSVESSPKMTELINKEKAQGVGVDPFQELQVLRLHYLKELGSIYGSQVSFPKLKLNKVDIENCPNLHQRPL
What is the function of this protein?
Probable disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At5g47250.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: CALR_ONCVO
Sequence: MQLSLLVGLVCFSAINAKIYFKEDFSDDDWEKRWIKSKHKDDFGKWEISHGKFYGDAVKDKGLKTTQDAKFYSIGAKFDKSFSNKGKSLVIQFSVKHEQDIDCGGGYVKLMASDVNLEDSHGETPYHIMFGPDICGPGTKKVHVIFHYKDRNHMIKKDIRCKDDVFTHLYTLIVNSDNTYEVQIDGEKAESGELEADWDFLPPKKIKDPDAKKPEDWDEREFIDDEDDKKPEDWDKPEHIPDPDAKKPEDWDDEMDGEWEPPMVDNPEYKGEWKPKQKKNPAYKGKWIHPEIEIPDYTPDDNLYVYDDIGAIGFDLWQVKSGTIFDDVIVTDSVEEAKKFGEKTLKITREGEKKKGKKTKKQKKKEKNEKIKKEKMKKRKRANRKKKK
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle.  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
What are the official names of this protein?
Calreticulin, 41 kDa larval antigen, Protein ral-1, RAL1 antigen.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: UFM1_CAEBR
Sequence: MSGEASAPAAKVTFKITLTSDPKLPFKVLSVPEAAPFTSVLRYAAEEFKVPAATSAIITNDGVGINPAQSAGNIFLKHGSELRLIPRDRVGGF
What is the function of this protein?
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (By similarity).  The so-called ufmylation requires the ufm-1-activating E1 enzyme uba-5, the ufm-1-conjugating E2 enzyme ufc-1, and probably the ufm-1-ligase E3 enzyme ufl-1 (By similarity).
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
Protein: PLPL_LODEL
Sequence: MMVGSSSEKKIPLYDEQNDYINEDHISEFAKALVWQDYDDVSTTAPTTPLNGPLDMGDLSLLGGELGNGSDDVVVGDDDDDDDDDDDDDDDDDDDKTKYSSPQLKAAQEINDEATEIGAVPATTKPDLISSKNDWFPINSENLNPNSKRTKFAKSSKSSKSKSTSPIRALQNEFRNSASFTLLRWPILTFVVIWVTILGFLYLAVRVYVALLEYFFTWTGERKRLRDKLRQSTTYKEWIENAKELDKYLGLDKWATNPKFSYYDSQTVQLTINKLKKARLNNSMPELLILLQGCLKRNFAGIENRQLYSHMYYGTKNLVQDYYKEVVICINKVIESNEINSETKYKFFKTVLQNFGKSALCLSGGACFAYTHFGIAKALLDQDLLPNIISGTSGGGLIAALLCTRTNEELKKLLVPQLARKITACEDPWYVWIPRLLKTGARFDSVAWARKSNFFTKGSTTFEEAMAMTGRKLNISTVPADPHSPVILCNDITSPHCIIWSTLLASSAVPGILNPVVLMMKNPVNGAVVPFSLGSKWRDGSLRTDIPIDALNTYYHVNFTIVSQVNPHISLFFFAPKGTVGRPVSMSKRKTAKEKFASFRGGFIATALEQLFRLEIKKWLQIVKSLDLLPHVLQQDWSNVWLQNFTGTITIWPRNRLIDFWYILSDPNEKQMEEIITKGERSMYPKILFIKNRLSIEKAIEKGRKTSTAELRETQMNVALASDDDEDYVPSDYSLAKFKDRIGVTSKDFDMLGSTLRDDDADADVDEDDNEDEDEEDEDENDYEEYDVEDLDDPYESDAFDPHIVLTKERRHTVY
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein LELG_00944.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL6_LISMF
Sequence: MSRIGKKTIVIPAGVTVTLNGSTATVKGPKGELVKEFNPEITINIEGNEINVSRPTDNKNHRALHGTTRAILNNMVVGVSEGYEKKLELIGVGYRAQKQGDKLVLNVGYSHPVEFVAPKGVDIEVPANTQVIVKGYNKEHVGELAANIRAVRPPEPYKGKGIRYEGEHVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: KLHL5_HUMAN
Sequence: MNVIYFPLHIFVVYSRAYTSLVLVGCTNLCAVLFARCLDDHLVSLRMSGSRKEFDVKQILKIRWRWFGHQASSPNSTVDSQQGEFWNRGQTGANGGRKFLDPCSLQLPLASIGYRRSSQLDFQNSPSWPMASTSEVPAFEFTAEDCGGAHWLDRPEVDDGTSEEENESDSSSCRTSNSSQTLSSCHTMEPCTSDEFFQALNHAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSKLLAYIRLPLLAPQFLADMENNVLFRDDIECQKLIMEAMKYHLLPERRPMLQSPRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLKSVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLSDCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVTVKL
What are the official names of this protein?
Kelch-like protein 5.
Protein: YQGE_SHIFL
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: NU6M_BALMU
Sequence: MVTYIVFVLSIIFVISFVGVSSKPSPIYGGLGLIVGGGAGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLGAFILGLVVESLIVIYALKSGEVKIVFEFDGLGDWVIYDTGGSGVFSEEATGIAALYSYGVWLVIVTGWSLFVSVVIIMEITRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL17_POLAQ
Sequence: MRHGNGLRKLNRTSSHRLAMLRNMSNSLLEHEVIKTTLPKAKELRMVVEPLITLGKKDNLANRRLAFNRTRDRDIVTKLFTELGPRYATRPGGYLRILKFGFRHGDNAPMALVELVDRPEVEETAVVAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PDXD1_DANRE
Sequence: MGNHLSDAMKILESGKLETEQGQEGRKMSWKEIPGPLQGDGQDVVSILQLVQNLMHGDDEEQGHRMQFVGEQGHMALLGHSLAAYISVLERERLRKLTTRILSDTTLWLCRLFRYENGSAYFHEDDREGLLKVCRLVMNTHYEDFTTEGFTALSSKHPVIYQSAACRPGLGQHLCSQLGLPLSCLCVVPCNTMFGSLHQMDVALLDKLVKDDRDSGKLPLLLIANAGTPGAGHTDKLSRLKELCVQYNMWLHVEGVNLATLVLGQVSSTVTAATKCDSMTLTPGPWLGLPAVPAVTLYRHEDPALSLAAGLTSSQPVEKLRALPLWLSLQYLGHDGIVERIKHASQLSQQLLEHLKTLASIKTSVEDELNSPVVVFRFSHENSAPSSGGSVEGSYAGERDILDAFNRWLGDQLAEQVPLSGVDVVELEDEGTCVRFSPLMTAAALGTQENDVAALVEKLAEMIPLLCCTLRLRQDFRDEVLQQASLSYIEDLNWPGLGVVRFEPRTTDLDEDKRQDRVEKINSDLLKKLMELDTDLNFSGGPEFSEEKNCIFIGIATEDLDVAELVETIMSLGRDIEESGKLFENMTEVVRKGIQEAELQLQKANEEKLMEEGVLRQIPLVSSVLNWFSPVQASVKGRTFNLAEGCLDSTEPVYSIKAQMRKEDSPDSPKANTRRFPGQKLFRRPGAGSDSISETSSVSQLEESFRETLHSQAADEAEVPQERPAHILEETAIADQRVPEGQEAESVETIR
What are the official names of this protein?
Pyridoxal-dependent decarboxylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: PURA_PODAN
Sequence: MPTTIILGSQWGDEGKGKLSDILCQKAQICARAAGGHNAGHSVVANGVSYDFHLLPSGLINPNCENLIGSGVVVNVEAFFKELNALEEKGLKHVREKILISDRAHVNLTLHAAVDRAEEAQLEGNKKIGTTGRGIGPSYATKASRKGIRVHEIFKEAVFEKKLRTLAEGYKKQFGELFEYDVEEEIARFREYRKLLPNFVCDGPNFIDQAQKSGRDLLIEGANALMLDIDYGTYPYVTSSNTGFGGAVTGLALDYKQIKEVIGVVKAYTTRVGGGPFKTEDLGDAGTKLQEIGREWGVSTGRRRRCGWLDLVVLKYSQLINNYTSWNLTKLDILDTFPTIKVAVAYKDKETGEVIEHFPADLDYLDTLEVVYKEFEGWQTPITSVKTFDALPAQAQAYVKFIEEFTGIPVKWIGTGPARDDMIYL
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUD2_SCHGR
Sequence: QFGNYYQPQPTYSPPARQQVPILQYSNEVNPDGSYAYSYQTGNGIAAQEQGYLKNPGQRDLEAENVQGTFSYTAPDGTPISLRYVADENGFRAEGAHLPTPPPIPEAIARSLEVIARTPQQPFQPQPQYNPFRRF
What is the function of this protein?
Component of the abdominal endocuticle.
What are the official names of this protein?
Endocuticle structural glycoprotein SgAbd-2.
Protein: IM23_SCHJA
Sequence: MATLGTGMRCLKSCVFILNIICLLCSLVLIGAGAYVEVKFSQYEANLHKVWQAAPIAIIVVGVVILIVSFLGCCGAIKENVCMLYMYAFFLIVLLIAELVAAIVAVVYKDKIDDEINTLMTGALENPNEEITATMDKIQTSFHCCGVKGPDDYKGNVPASCKEGQEVYVQGCLSVFSAFLKRNLIIVACVAFGVCFFQLLSIVIACCLGQRIHDYQNV
What are the official names of this protein?
23 kDa integral membrane protein, Sj23.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NTAQ1_DROPS
Sequence: MTTDFLFPKIADCSYVSCYCEENVWKLCEQVKRTRPEELGTCYAVFVSNEGRTVPLWRQKAGRGDDQVVIWDYHVFFMHNPSPNRCLVFDLDTTLPFPTYFHKYVTETFRSDLALRPEHHRFFRVIPADTYLIEFSSDRRHMRRPDGSWIKPPPSYPPILSNTNMHCLGDFICMSAGKGPGAVYSLSEFVHNFYKSPNMVAQHNK
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, Protein tungus.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: STHA_PSEPW
Sequence: MAVYNYDVVVLGSGPAGEGAAMNAAKAGRKVAMVDSRRQVGGNCTHLGTIPSKALRHSVRQIMQFNTNPMFRAIGEPRWFSFPDVLKSAEKVISKQVASRTGYYARNRVDLFFGTGSFADEQTVEVVCPNGVVEKLNAKHIIIATGSRPYRPADIDFHHPRVYDSDTILSLSHTPRKLIVYGAGVIGCEYASIFSGLGVLVELVDNRGQLLSFLDSEISQALSYHFSNNNITVRHNEDYERVEGLDNGVILHLKSGKKIKADALLWCNGRTGNTDKLGLENIGIKVNSRGQIEVDEAYRTSVPNIYGAGDVIGWPSLASAAHDQGRSAAGSIVDNGSWRFVNDVPTGIYTIPEISSIGKNEQELTQAKVPYEVGKAFFKSMARAQIAGEPQGMLKILFHRETLEILGVHCFGYQASEIVHIGQAVMNQPGELNNLKYFVNTTFNYPTMAEAYRVAAYDGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_AMIAM
Sequence: MRNAEVSRNTLETKIAVAINLDGTGVSKLNSGVGFFDHMLDQIARHGMMDISVECQGDLHIDAHHTVEDVGIALGQAFSRALGDKKGIRRYAHAYVPLDEALSRVVLDISGRPGLEFNVEFTRARIGEFDVDLVREFFQGFVNHAALTLHVDNLRGKNAHHQAETIFKAFGRALRAAVELDPRMVGIMPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFMM3_STRLA
Sequence: MRRMLYAQLPSRALVVVAQLGIADILAEGPADISTLAERTSTDAVALARLLRGLAVFGVFEEGAEQVYSLTPLGEALTSGHPASALPSATLVAGQFGAAWGDLLETVRTGQSPFERSRGVSLFTHMEQDEELRAVFDDSQGRGLALELDEILRAIDFSAYPTVVDVGGSDGTFLRRILSAHPDISGIVFDLPGSTSLQAERPTADPLEGRYSVATGDFFDSLPEGGDLYLLSHILHDWDDDRAVQILRTCRAAMSDDATLMVVDLIAANRGQRDERLHTAALMDLYMLSLFGGNGGQERTAAQVEVLLSKAGFRITRVDSLPSGMNVIRAVRAA
What is the function of this protein?
O-methyltransferase that mediates the methylation of 3-hydroxy-5-methyl-L-tyrosine (3-OH-5-Me-Tyr) into 3-hydroxy-5-methyl-O-methyltyrosine (3-OH-5-Me-OMe-Tyr), a core structure of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family.
What are the official names of this protein?
O-methyltransferase SfmM3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: KBAY_ECODH
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: ZAPB_SHEWM
Sequence: MSLELLSKLETKIQTALETIELLKMELEEEKQKSIGLAEQNQQLSQDLNSWNEKVTGLVGLLNEEVN
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: PTH_RICFE
Sequence: MILVIGLGNPGKEYQYTRHNIGFIAIEKIANQYNSSFSIKKKFNCEIAETISDGQKIIFIKPTTYMNLSGKSVISVKTYYNIQSAKIFVIHDDIDLETGRIKFKTGGGNGGHNGLKSIDGVIGNNYNRIRVGVGRPQNNQDVADYVLNNFLKSEYETALQAIDRIANNFDLILENKLEEFKNKIV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.