PharMolix/UniProtQA huggingface dataset:
Protein: HNRPK_PONAB
Sequence: METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF
What is the function of this protein?
One of the major pre-mRNA-binding proteins.  Binds tenaciously to poly(C) sequences.  Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences.  Can also bind poly(C) single-stranded DNA.  Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression.  When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction.  As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53.  This interaction is necessary for the induction of apoptosis, but not cell cycle arrest (By similarity).  As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein K, hnRNP K.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Cell projection, podosome.
Protein: RL10_CHLPB
Sequence: MKREKKEQIVKDVAEKLQKAQGIYLTEFQGLDVEKMAELRNEFRKAGVEYQVAKNTLIKKALENVNGGDRLADGLVNTTGMAIGYDDPIAPAKIIEKFGKKNEMLKFKMATIDGSVFEADKLQVLSKMLSKTENIGRFAGMLNNVISSVPMVINAVMSDLVSVIDQVAKQKQD
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ATPL_CYAP4
Sequence: MDPQIASASVLAAALAIGLAAIGPGIGQGNASGQAVEGIARQPEAEGKIRGTLLLTLAFMESLTIYGLVIALVLLFANPFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PDXT_STRP7
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PAND_STAEQ
Sequence: MIRTFMNSKIHRARVTESNLNYVGSITIDANILDAVDILPNEKVAIVNNNNGARFETYVIAGERGSGKMCLNGAASRLVEVGDVIIIMTYAQLNEDEMVDHSPKVAVLNENNEIIEMINEKENTISNV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALSA_ARATH
Sequence: MARVYSNWDRLVRATLRREQLRNTGQGHERVSSGLAGAVPPSLGRATNIDAILQAADEIQSEDPSVARILCEQAYSMAQNLDPNSDGRGVLQFKTGLMSVIKQKLAKRDGASIDRDRDIERLWEFYKLYKRRHRVDDIQKEEQKWRESGTTFSSNVGEILKMRKVFATLRALIEVLEVLSRDADPNGVGRSIRDELGRIKKADATLSAELTPYNIVPLEAQSMTNAIGVFPEVRGAVQAIRYTEHFPRLPVDFEISGQRDADMFDLLEYIFGFQRDNVRNQREHLVLTLSNAQSQLSIPGQNDPKIDENAVNEVFLKVLDNYIKWCKYLRIRVVYNKLEAIDRDRKLFLVSLYFLIWGEAANVRFLPECICYIFHNMAKELDAKLDHGEAVRADSCLTGTDTGSVSFLERIICPIYETISAETVRNNGGKAAHSEWRNYDDFNEYFWTPACFELSWPMKTESRFLSKPKGRKRTAKSSFVEHRTYLHLFRSFIRLWIFMFIMFQSLTIIAFRNEHLNIETFKILLSAGPTYAIMNFIECLLDVVLMYGAYSMARGMAISRLVIRFLWWGLGSAFVVYYYVKVLDERNKPNQNEFFFHLYILVLGCYAAVRLIFGLLVKLPACHALSEMSDQSFFQFFKWIYQERYFVGRGLFENLSDYCRYVAFWLVVLASKFTFAYFLQIKPLVKPTNTIIHLPPFQYSWHDIVSKSNDHALTIVSLWAPVLAIYLMDIHIWYTLLSAIIGGVMGAKARLGEIRTIEMVHKRFESFPEAFAQNLVSPVVKRVPLGQHASQDGQDMNKAYAAMFSPFWNEIIKSLREEDYLSNREMDLLSIPSNTGSLRLVQWPLFLLCSKILVAIDLAMECKETQEVLWRQICDDEYMAYAVQECYYSVEKILNSMVNDEGRRWVERIFLEISNSIEQGSLAITLNLKKLQLVVSRFTALTGLLIRNETPDLAKGAAKAMFDFYEVVTHDLLSHDLREQLDTWNILARARNEGRLFSRIAWPRDPEIIEQVKRLHLLLTVKDAAANVPKNLEARRRLEFFTNSLFMDMPQARPVAEMVPFSVFTPYYSETVLYSSSELRSENEDGISILFYLQKIFPDEWENFLERIGRSESTGDADLQASSTDALELRFWVSYRGQTLARTVRGMMYYRRALMLQSFLERRGLGVDDASLTNMPRGFESSIEARAQADLKFTYVVSCQIYGQQKQQKKPEATDIGLLLQRYEALRVAFIHSEDVGNGDGGSGGKKEFYSKLVKADIHGKDEEIYSIKLPGDPKLGEGKPENQNHAIVFTRGEAIQTIDMNQDNYLEEAIKMRNLLEEFHGKHGIRRPTILGVREHVFTGSVSSLAWFMSNQETSFVTLGQRVLAYPLKVRMHYGHPDVFDRIFHITRGGISKASRVINISEDIYAGFNSTLRQGNITHHEYIQVGKGRDVGLNQIALFEGKVAGGNGEQVLSRDVYRIGQLFDFFRMMSFYFTTVGFYVCTMMTVLTVYVFLYGRVYLAFSGADRAISRVAKLSGNTALDAALNAQFLVQIGIFTAVPMVMGFILELGLLKAIFSFITMQFQLCSVFFTFSLGTRTHYFGRTILHGGAKYRATGRGFVVQHIKFADNYRLYSRSHFVKAFEVALLLIIYIAYGYTDGGASSFVLLTISSWFLVISWLFAPYIFNPSGFEWQKTVEDFEDWVSWLMYKGGVGVKGELSWESWWEEEQAHIQTLRGRILETILSLRFFMFQYGIVYKLDLTRKNTSLALYGYSWVVLVVIVFLFKLFWYSPRKSSNILLALRFLQGVASITFIALIVVAIAMTDLSIPDMFACVLGFIPTGWALLSLAITWKQVLRVLGLWETVREFGRIYDAAMGMLIFSPIALLSWFPFISTFQSRLLFNQAFSRGLEISIILAGNRANVET
What is the function of this protein?
Involved in sporophytic and gametophytic development.  Required for normal plant development and for the proper accumulation of callose at cell plates, cll walls and plasmodesmata.  During pollen formation, required for the entry of microspores into mitosis.  During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals.  Required for proper cell division and tissue patterning throughout plant organs, including stomatal patterning.
What are the official names of this protein?
Callose synthase 10, 1,3-beta-glucan synthase, Protein CHORUS, Protein GLUCAN SYNTHASE-LIKE 8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 48 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIME_MOUSE
Sequence: METVHSTFLLLLFVPLTQQAPQSQLDSHVNYEYATGNSEETKFSQDYEDKYLDGKSIKEKETMIIPDEKSLQLQKDEVIPSLPTKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKHNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSLTDDTFCKANDTRYIRERIEEIRLEGNPIALGKHPNSFICLKRLPIGSYF
What is the function of this protein?
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
What are the official names of this protein?
Mimecan, Osteoglycin.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HSLU_BACMK
Sequence: MHLHFTPRQIVEKLDQYIIGQKDAKKAVAVALRNRYRRSKLVENLRDEIAPKNILMIGPTGVGKTEVARRMAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRIVKEEMVVKVQDKAEEQANQRLVEILVPSPEKQSGFKNPLEMLFGGNQNSNQTSDAQEDDEIEKKRQDVERKLAAGLLEDEVISIEVTEQQSSMFDMLQGTGMEQMGMNFQDALGSIMPKKTKKRKLSVKEARKLLTNEEAQRLIDMDEVTQEAVYRAEQLGIIFIDEIDKIAGKQSNSVDVSREGVQRDILPIVEGSNVATKYGSVKTDYILFVAAGAFHMSKPSDLIPELQGRFPIRVELTKLSADDFVKILIEPDNALIKQYTALLATEGIEIEFSDEAIRKIAEIAYQVNQDTDNIGARRLHTVMEKLLEDLSFEASEITLEKITITPQYVEEKLATIAKNKDVSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_RHOOB
Sequence: MFLGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKGQDHSLAVYPREEFTALARKAAAASRSDPEARAFVRGLAAGTDEQHADAQGRITLSADHRRYAGLSKDCVVIGSVDFLEIWDAQAWQTYVEANEENYSQATGIALGEIV
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PROF6_CORAV
Sequence: MSWQAYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVAAAKYMVIQGEPGVVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCDMVVGRLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-6, Allergen Cor a 2, Pollen allergen Cor a 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ABCA_ASPFU
Sequence: MNESHEAGKNSSTNVEEREEEVLRLARQFTEQSSYSTAGQTPFAAEAGSALDPNGERFNARAWCKAMLQMHIGDKEAHPLRTLGVAFSNLNVHGFGSDTDYQKSVGNVWLKTLSLARIAFGQKQRKVDILQNLEGLVEAGEMLVVLGPPGSGCSTFLKTIAGETYGFHVDKNSNINFQGIAKQMAHEFRGEAIYTAEVDVHFPKLTVGDTLYFAARARTPRHIPGGVNATQYAGHMRDVIMAMFGISHTKNTIVGNDFIRGVSGGERKRVSIAEACLSNAPLQCWDNSTRGLDSANAIEFCKTLRMQADINGTTACVSLYQAPQAAYDYFDKVLVLYEGREIYFGPTSMAKHYFLQMGFVCPDRQTDADFLTSMTSHLERVVQPGYEDRVPRTPDEFAARWKASPQRAQLMQHIKSYNAKFALDGEYLDKFKQSRRAQQAKAQRVSSPYTLSYVQQVKLCLWRGYQRLKADPSVTISSLFGNTIISLVIASIFYNLKADTSTFFQRGALLFFAVLMNALGCGLEMLTLYAQRGIIEKHSRYALYHPSAEAFSSMIMDLPYKILNAITSNIVLYFMTNLRREPGAFFFFVFTSFILTLTMSMFFRSMASLSRSLVQVLPFSAVLLLGLSMYTGFAIPTGYMLGWARWIAYINPISYGFESLMINEFHNRDFPCMDYVPSGPGYTDVGLNNRVCSTVRSVPGQAFVNGNAYIESAYSYTASHKWRNIGVIFAYMFLLGAVYLVATDFITEKKPKGEILVFPRGHKALKKGKSDEDLEGGGGRSATVEKIGSDGLAMIERQTAIFQWKDVCFDIKIGKENCRILDHVDGWVKPGILTALMGVSGAGKTTLLDVLATRTTMGIISGEMLVDGQPRDESFQRKTGYAQQQDLHLSTATVREALEFSALLRQSAHVPRQEKIDYVTEVIKLLDMTEYADAVIGVPGEGLNVEQRKRLTIGVELAARPQLLLFLDEPTSGLDSQTSWAILDLLDKLKKNGQAILCTIHQPSAMLFQRFDRLLFLQAGGRTVYFGEIGQNSQILIDYFVRNGAPPCPPDANPAEWMLDVIGAAPGSHTSINWFETWRRSPEYARVQEHLAELKHERRHQTNLFRTTSGQKREDKDSYREFAAPFWAQLYQVQVRVFQQIWRSPTYIYSKTALCVLSALFVGFSLFHTPNTIQGLQNQMFGIFMLLTLFGQLIQQIMPHFVAQRALYEVRDRPAKTYSWKAFLIANIVVELPWNSLMSVLMFLCWYYPIGLYRNAEPTDAVHLRGTQMWLMIWTFLLFSSTFAHFMIAAFDAAENAGNLGNLLFLLCLLFCGVLATPDQLPRFWIFMYRVSPFTYLVSGMLSVGISNTNVTCADNEYLRFDPVNGTCGEYMGSYMSNLGGYLADEMATANCSFCPIKETNVFLGRVSSSYSDIWRNFGLMWVFIVFNIFAACSLYWWVRVPRDKKPVAKAE
What is the function of this protein?
ABC transporter that seems not to be involved in the efflux of toxic substances, at least not the classical compounds such as itraconazole, amphotericin B, voriconazole, posaconazole, ravuconazole, or echinocandins.
What are the official names of this protein?
ABC multidrug transporter A-1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABPL_GINCI
Sequence: VEAFLGSWKLQKSHNFDEYMKNLDVSLAQRKVATTVKPKTIISLDGDVITIKTESTFKSTNIQFKLAEEFDETTADNRTTKTTVKLENGKLVQTQRWDGKETTLVRELQDGKLILTCTMGDVVCTREYVREQ
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, liver, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOLA_MYCTU
Sequence: MSEAKPLHLVLGDEELLVERAVADVLRSARQRAGTADVPVSRMRAGDVGAYELAELLSPSLFAEERIVVLGAAAEAGKDAAAVIESAAADLPAGTVLVVVHSGGGRAKSLANQLRSMGAQVHPCARITKVSERADFIRSEFASLRVKVDDETVTALLDAVGSDVRELASACSQLVADTGGAVDAAAVRRYHSGKAEVRGFDIADKAVAGDVAGAAEALRWAMMRGEPLVVLADALAEAVHTIGRVGPQSGDPYRLAAQLGMPPWRVQKAQKQARRWSRDTVATAMRLVAELNANVKGAVADADYALESAVRQVAELVADRGR
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  Pol III also exhibits 3'-5' exonuclease activity.  The delta subunit interacts with the gamma/tau subunit to load the beta sliding clamp (dnaN) onto the DNA (By similarity).
What are the official names of this protein?
Probable DNA polymerase III subunit delta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase HolA subunit family.
Protein: DNLI3_DICDI
Sequence: MSEDKSGSFYSMYKLCGQLEKESSHSGKTQLIKSFCNVFKGDLYLLAKLMLCKEDKRVFRIKDKAMLKICSHIWDCDLDDMIEDLDNGDFTETCKKFYIEYGKYPEKSTLTLKEVDQVLDSLTVSGKFEDQVKIINKLLKRCTPFDFRLVCRIIDSDLKINTGAKFFLDAFHPQAYDAFKKANNLKGVIEKIQQHDFDNDNGDGDDGDGDDNDDDDGDGDSDSDKKKKKSSGGSGSDSGSKKKSKSFEVAIKLMTPIKPMLPKAVKTVEGVVKSSECFYAEIKYDGERIQIHKDGNQFSCYSRNLKPLMPWKVDEVKPYIPKSTKAQQMILDGEILLMDTKTSQPLPFGTLSAHKKNGFKDATVCVFLFDILYLNGKSLIHLPLKERREILEKNVMVVKNRIEFSEVTIVNGASEKSKLTALLNRVFKEKLEGLVIKDAMSEYEPGCRHWIKIKKDYIHGMADSADLIAVGGYYGSGSMGGLVTVFLMVCYDKQNKIYKTVVKASGGLDDNMIAKLQPKVTSTMTKISKEVSKIPYWLDCPKQYAPDFIVKDIKQAMIFEIESAEFTKSDHHTTGYSMRFPRILKIRHDKDYKTATTLEELVEIGKDIKIVPVGKGDNNSPTTTTTTTTTTTTTTSSKLIKKQQLSDDDDDNDKDSKQQQQEPSKLKFVSDDLLDPFNDKSDDESNKIFILNYVDNSGIWNEKGLSGAIGKKWPSIPKSFSQGDSNIIKSGEIRVEKVKDDSISTNKKVFICNLSCIIPPKSKKESYTFSLKEFKSAIKEAKGAINQKKASVHLAKPQFTSPSWSELDEVLTKELYNSGIKVFVHSISKSSPTTTSPTTTSPTTTSPKITSPSSSSSPSNKLSPLKRGRDEKLEHEIIKDIEPSLPIFEDVNAVIDSKTIDQVDVKRLINSIKTMGGRVSDKWQQVGIGKTTHLICNGMSDLYLHVDRLGGTIVLPNWVDQCFGSDKLLPLHEDYIYFNKKDHPDYSQSSSSSSMSIEEEKIVVTTTSDDPSEGNQQQQDKKVIKESKIIQSKDHSSTTTIDTKITITSTNNNNNGNDNNKTRKKQHLLSIFQECIIFLHDNVNDRETLKRYIIAYGGDISDSVNDKTTHLVASLPNNFSNVKPKDLFKSIINNNSKNNNNNNNNNNNGIIVNSLWLWDSINMSDLLDVKNYKLF
What is the function of this protein?
The alpha isoform interacts with DNA-repair protein XRCC1 and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.  The beta isoform does not interact with XRCC1 and may be specifically involved in the completion of homologous recombination events that occur during meiotic prophase.
What are the official names of this protein?
DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_UREPA
Sequence: MSKLTIEQFIAAIKEMSMLELNDLVKAIETEFGVSAAAPVAAAAAPVAAEAPTEVTIKLVEAGTNKVGVIKLIREITGLGLMEAKTAAETAGSVIKEDVKTEEANEIKKKFDELGAKVQLV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: QCR6_NEUCR
Sequence: MGFWDAVTDLIDAATPWATVEAEAPADTPAETAPASESTEETTAETKAEESAPAAEEPEEEAEEEEEEEEDEDEIVDPKETLEEECRNSKECAPAKHHYDECAARVTGAGADNKEDCVEEFFHLVHCATQCAAPKLWNTLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 6, mitochondrial, Complex III subunit 6, Complex III subunit VI, Ubiquinol-cytochrome c oxidoreductase subunit 6, Ubiquinol-cytochrome c reductase complex 14 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRH/QCR6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: CH602_STRCO
Sequence: MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIANSKIGNVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGEVISEEVGLKLENATLDLLGSARKVVITKDETTIVDGAGSADQVQGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQASQVFEKLELTGDEATGANAVKLALEAPLKQIAVNGGLEGGVVVEKVRNLTVGHGLNAATGEYVDMIAEGIIDPAKVTRSALQNAASIAALFLTTEAVIADKPEKAAPAGAPGGMPGGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BRUMB
Sequence: MFNTHKVEIEWGGRPLTLETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAEEHFFPEGVEETEMSAEQFATIFKHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_RHOPT
Sequence: MTDSNQPTPLQARKSGALHGTARVPGDKSISHRALILGALAVGETRISGLLEGEDVINTAKAMRALGAKVERTGDCEWRVHGVGVAGFATPEAPLDFGNSGTGCRLAMGAVAGSPIVATFDGDASLRSRPMRRIVDPLELMGAKVVSSSEGGRLPLALQGARDPLPILYRTPVPSAQIKSAVLLAGLSAPGVTTVIEAEASRDHTELMLQHFGATIVTEAEGAHGRKISLTGQPELRGAPVVVPADPSSAAFPMVAALVVPGSDIELTDVMTNPLRTGLITTLREMGALIEDSDVRGDAGEPMARFRVRGSKLKGVEVPPERAPSMIDEYLVLAVAAAFAEGTTVMRGLHELRVKESDRLEATAAMLRVNGVAVEIAGDDLIVEGKGHVPGGGVVATHMDHRIAMSALAMGLASDKPVTVDDTAFIATSFPDFVPMMQRLGAEFG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPCS2_CANLF
Sequence: MAAASAQGGRTGGGGGSSGPGGGPTCGSGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLATERKIK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:3511473).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GMHA_NITSB
Sequence: MLEHIEKELLEHQKTFEKVWEELRFHIYTASIICIEALKNQKKIMLCGNGGSAADAQHIAAELVGRFKKERRSLPAIALSVDTSALTAIGNDYGFELVFARQVEGLAQKGDVLIGISTSGESENVLRAMEEAKKRGCKTIGLLGKDGGRIKDLCDAAIVVPSSQTPRIQEMHIMIGHILCSLIDESF
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H1_ARATH
Sequence: MSDSGEPKPSQQEEPLPQPAAQETQSQQVCTFFKKPTKSKNIRKRTIDADEEDGDSKSESSILQNLKKVAKPDSKLYFSSGPSKSSTTTSGAPERSVFHYDSSKEIQVQNDSGATATLETETDFNQDARAIRERVLKKADEALKGNKKKASDEKLYKGIHGYTDHKAGFRREQTISSEKAGGSHGPLRASAHIRVSARFDYQPDICKDYKETGYCGYGDSCKFLHDRGDYKPGWQIEKEWEEAEKVRKRNKAMGVEDEDDEADKDSDEDENALPFACFICREPFVDPVVTKCKHYFCEHCALKHHTKNKKCFVCNQPTMGIFNAAHEIKKRMAEERSKAEQGL
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 1, AtC3H1.
Protein: Y1004_METJA
Sequence: MKVRDLMDKNFAKIYVDETVEDAINLLKKKKRFSAPIVDKEDRLVGWVTTLELLGISEKDFKKPITEFMRPVEEVITVYEDDEARNVVLKFVKYKVVSIPVLTRDGRVIGMVRNCDVVKTLAKLYEIPVYKIFKELHNHIGDISWEELMEAAAVVTKRMTGEDITPQEYEERIKKTTFGKAIWACGGLEKFFVGLIEIGMVALARKLAKRRKGG
What are the official names of this protein?
Uncharacterized protein MJ1004.