PharMolix/UniProtQA huggingface dataset:
Protein: ATG4_ASHGO
Sequence: MGFLIAYVFNLSPCSGDEMFETIGLAIIHFEGLNTNRVSKCNQNWHQESKQVAMELIQKVSQGLWELENCDTVNSVVVLGKEYPPVPEQRQEERHENGVNMFQHIFTRQGRWNEEFLADVHTRLHFTYRTRFVPIPRHPNGPSPMSISVMLRDNPLNVIENVLNNPDCFQTDIGWGCMIRTGQSLLANALQRACLGRDFRIDDNAANEHELRIIKWFEDDPKYPFSLHKFVQEGFSLSGKKPGEWFGPSATSRSIQALVAKFPACGIAHCVISTDSGDVYMDEVEPLFRADPSAAVLLLLCVRLGVDVVNEVYWEHIRHILSSEHSVGIAGGRPSSSLYFFGYQDEHLFYLDPHKPQLNLASYQQDLDLFRSVHTQRFNKVHMSDIDPSMLIGILLNGKDDWQLWQQHIASSQIIHLSDSKPVDLMLDHQLESAILGDRYLSEDGQGPSSKVDTGDYIDVGSFVPCTDSSCKINESEDEYQDVKCKNQRIVVVGETTTNGSPEVEVEKVLVEKETIPVRSK
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: UVRC_YERPA
Sequence: MTDLFDYKEFLKTVTSQPGVYRMYDTAGTVIYVGKAKDLKKRLTSYFRAQVANRKTETLVKNIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPLIFLSADEHPRLAVHRGAKHEKGEYFGPFPNSYAVRETLALLQKLFPVRQCENSVYRNRSRPCLQYQIGRCSGPCVEGLVSEEEYQRQVDYVRLFLSGKDQQVLTQLITRMEEASQQLHFEDAARIRDQIQAVRRVTEQQFVSGDSEDLDVIGVAFDAGLACVHVLFIRLGKVLGSRSYFPKVPAGTELSEVVQTFVGQFYLQGSQGRTLPGEILLDFTLTEKDLLASSLSELAGRKIQIQSRPRGDRARYLKLARTNASTALITRLSQQSTIHQRMKELAKVLKLDEINRMECFDISHTMGEQTVASCVVFDANGPVRSEYRRYNISGITPGDDYAAMAQVLKRRYGKALDDQKIPDVIFIDGGKGQLSQAFDVFASLNVPWDKQKPLLVGVAKGSDRKAGLETLFLASEGEGFSLPPDSPALHLIQHIRDDSHNHAITGHRQRRSKVKNTSALEMIEGVGPKRRQVLLKYMGGLQPLFNASVEEIAKVPGISQALAEKIHNALKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_ECOHS
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SUCD_RICPR
Sequence: MAILINKKTKVICQGFTGSQGTFHSEQAIAYGTNMVGGVTPGKGGHTHLNLPVYNTVHEAKAKTGANASVIYVPPGFAADSILEAIDAKIEVVVCITEGIPVLDMIKVKRALIGSKTRLIGPNCPGVITPGECKIGIMPGHIHKIGDIGIVSRSGTLTYEAVAQTTAAGLGQSTCVGIGGDPVNGTSFVDCIEMFLQDDETKAIIMIGEIGGSAEEDAADFIKQSKIKKPIVSFIAGITAPADKRMGHAGAIISGGKGSAEDKVEVLQSAGVIITRSPADIGKTMLDLLNKI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
Protein: RS8_THIDA
Sequence: MSMSDPIADMLTRIRNAQQVEKMAVSMPSSKVKVAIAKVLKDEGYIEDFAVRGEAGKPELELQLKYYAGRPVIEHIERVSKPGLRIYKGAGDLPRVKNGLGVAIVSTSSGVMTDRHARAKGVGGEVLCFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GALAB_RHIME
Sequence: MTDLVPFSGRTLSEAASELGEGPTFDPGTGTAWWFNITGRELHELHLESGRKAIHPLPFLGSVLAVIDPLRQLIASDQGLFVRDTESSKLGHFATLEEKPGNRSNDGRIHPCGALWIGTMGRSAEKHAGAIYHVAGSRVTKLYSNITIPNAICFSPDGATAYFTDTDVNQLMRVDIDPATALPTGDPVLLSDESTSPGGVDGAVCDADGLIWNARWGASAVEVYKPDGQKVARYAVPATQPSCPAFVGAKAERLLVTSAWQGMDDAARAADPHAGKTFELGIEVKGRFEPAFRL
What is the function of this protein?
Involved in the degradation of galactose via the DeLey-Doudoroff pathway.
What are the official names of this protein?
Putative sugar lactone lactonase.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
Protein: ATPA_SCHPO
Sequence: MLRQAGTRLLKVPVCGLRPSITLKRGYAEKAAPTEVPSILEERIRGAYNQAQMMESGRVLSIGDGIARISGLSNVQAEELVEFSSGIKGMALNLEADTVGCVLFGNDRLVREGEVVKRTRHIVDVPVGEALLGRVVDALGNPIDGKGPIKTTERRRVQLKAPGILPRTSVCEPMQTGLKAIDSMVPIGRGQRELIIGDRQTGKTAIALDTILNHKRWNNSSDESKKLYCVYVAVGQKRSTVAQLVQKLEENDSLKYSIIVAATASESAPLQYLAPFSGCAMGEWFRDNGKHGLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSPKHGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLESELFFKGIRPAINVGLSVSRVGSAAQVKAMKQVAGQIKLFLAQYREVASFAQFGSDLDAGTRATLDRGLRLTELLKQPQYSPLAVEEQVPLIYCGVKGYLDKIPVDRVVEFEHKFIPYLRSSGAEIMEAIRKEGVLSKTTEDSLKAVIKEFLSSF
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: PLD5_MOUSE
Sequence: MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSEDAPFHLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPAACQGQRLFEKLLQLTSQNIEVKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSSKRTYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRDNRSIIKQLKDVFERDWYSPYAKSIQPTKQPNCSSLSKLKSPSKQPAMANATGREPLSV
What are the official names of this protein?
Inactive phospholipase D5, Inactive PLD 5, Inactive choline phosphatase 5, Inactive phosphatidylcholine-hydrolyzing phospholipase D5.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYB_TAMTE
Sequence: MTHIRKTHPLFKIINQSFIDLPTPSNISAWWNFGSLLGVCLVIQTLTGLFLAMHYTSDTITAFSSVTHICRDVNYGWLIRYIHANGASMFFMCLYLHVGRGLYYGSYLYLETWNIGVILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAMTHLLFLHETGSNNPLGLSSDMDKIPFHPYYTIKDILGLLIMIATLVTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVCSILVLMIMPLLHTAKQRSMMFRPLSQLLFRLLVANLLILTWIGGQPVEHPFIIIGQVASISYFSIILILMPLAGILENHLMKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPB_PROMT
Sequence: MAASATATVGTKGVVRQVIGPVLDVEFPAGKLPSILNALRIEGKNPAGQDVALTAEVQQLLGDHRVRAVAMSGTDGLVRGMEALDTGAPISVPVGEATLGRIFNVLGEPVDEQGDLKNVTTSPIHRSAPSLTDLETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINSEDLTKSKLALCFGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGELQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLARALAAKGIYPAVDPLDSTSTMLQPSVVGDEHYRTARAVQSTLQRYKELQDIIAILGLDELSEEDRKTVDRARKIEKFLSQPFFVAEIFTGMSGKYVKLEDTIKGFNMILSGELDQLPEQAFYLVGSIDEVKAKAEKIASEAKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: DAPA_LACH4
Sequence: MATLIDADLLTAIVTPFDENKKIDFDSLKKLTNYLIDQGCNGFVIGGTTGETPTLTHDEKIELYKQFGQIVNGRAVVIAGTGSNNTAETIKFTNEVAEIDGIDYALVVVPPYNKPNQRSMVAHFTAVNDNVKMPFLIYNIPGRTGVRMEKETVVQLSQLDNIKGIKQCASLEEMEYIIDHKAAGFQVFTGEDTQALTARLLGANGVVSVASHIYTKEMRRMYDALYEGKYPEAAKIQRWLTLRMQALFMYPSPSPVKAVLNAQGFETGDCRLPLVALNDEEKVTLAQHLGLEDNALLQKLPLDLGKDLEND
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EID2B_HUMAN
Sequence: MAEPTGLLEMSELPGDSSVPQVGTASGVSDVLRGAVGGGVRVQEAREGPVAEAARSMARMPGPVPGPIPSSVPGLASAPDPHQQLAFLEINRQLLFREYLDGSSMIPVRLLRDFEERRRLFVEGCKAREAAFDADPPQMDFAAVAFTVALTASEALSPLAD
What is the function of this protein?
Acts as a repressor of MYOD-dependent transcription, glucocorticoid receptor-dependent transcription, and muscle differentiation.
What are the official names of this protein?
EP300-interacting inhibitor of differentiation 2B, EID-2B, EID-2-like inhibitor of differentiation 3, EID-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_HELPH
Sequence: MPNRGVVLLDGQALAYDIEKDLKNKIQTITAQTHKRPKLAVILVGKDPASITYVNMKIKACQRVGMDFDLKTLQEDITEAKLLSLIKDYNTDQNISGVLVQLPLPRHIDSKMVLEAIDPSKDVDGFHPLNIGKLCTQKESFLPATPMGVMRLLKHYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHILTKDISFYTQNADIVCVGVGKPDLIKASMLKKGAVVVDIGINHLNDGRIVGDVDFNNAQKVAGFITPVPKGVGPMTIVSLLENTLIAFEKQQRKGF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ECHI_DICCH
Sequence: MLEIFDVSFSLMSNNKLDEVFTLRKDTFKDRLDWAVNCINGMEFDEYDNEHTTYLLGVKEGKVICSVRFIEIKYPNMITGTFYSYFDNLKIPEGNYIESSRFFVDRDRVRNLIGTRNPACVTLFLAMINYARKYHYDGILTIVSHPMLTLLKRSGWRISIIQQGLSEKQERIYLLHLPTDDDSRHALIERITQMTQAESEQLKTLPLLVPLA
What is the function of this protein?
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to the EchR transcriptional regulator.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein EchI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: FABH_BURL3
Sequence: MAQSTLYSRVLGTGSYLPPDRVTNQQLTDRLAKEGIETSDEWIVARTGIHARHFAAPDVTTSDLALEASRRAIEAAGIDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIKNGGAAFDVQAVCSGFAYAMATADSFIRSGQHRTALVIGAETFSRILDFKDRTTCVLFGDGAGAVILSASEEPGVLGSALHADGSYSHILCTPGNVNRGVIEGSAFLYMDGQAVFKLAVNVLEKVAIEALAKANLAPEQIDWLIPHQANIRIMTSTCRKLGLPQERMVVTVDQHGNTSAASIPLAFDTAVRDGRIQRGQHVLIEGVGGGFTWGASVFRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ4_PICGU
Sequence: MFSIVSSRPKSLVRPNSRSIVLPALVALTSIIFSKDNRLADKMESGKLHYKDVNSTFNVDKPYKSRSKPNYPGHVPLNAFEKLLMMAGSSIGSYLHPERNEFIVGLGESTAFTPVLRRLQRQMLSDPVGRQILRERPRITSESLDLDYLRSLPKNTIGSAYIQWLDREGVSPDTRVPVRYIDDEELAYIYQRYRECHDFYHAITGLPIIIEGEIAVKVLEFTNIGIPMSGLGGLFAPLRLRPKQRERLYGIYYPWAFKSGLNSKPLINVYWEKILEQDINEFRRDMGIEQPPDLRELRRKQKKLPEPERENAN
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MIAA_EHRRW
Sequence: MNNVLIITGPTASGKSKISIKIAQDNNGVIINCDSKQIYKEIPIITDQPKLNETFIPHKLYGYVSAVKQYSVAEWVNDLKREIYQTFTENKLPIITGGSGMYISSIIYGLSQIPAIEENIRYQTKQLFNTLGNKEFYSLLIEKDPIAKRLHYNNSYQLLRAYEVIEQTGTSIFRLQEELKRKPLFDNFTLCILVPQRQEVYKKINDRFISMINSSVIEEVKNLISLNIPNHFPAMKAHGIPEIIQYLTNKISIEKAIEIAQRNTRHYAKRQYTWFKNQFPNALFYESQDQLLKFISKKFK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NUOB2_SORC5
Sequence: MTSNLNLMAPPRGWEAKYESDGGGVITTSVDQTVNWLLNWGRSNSVWYMLFGLACCAIELMQTGGPRGDLERFGAAPRPSPRSSDLFIIAGTLTYKMATRVKRLYDQMSEPRFVISMGSCSNCGGLFQYAYSVCKGVDQIIPVDVYVPGCPPRPEALLEGLLKIQEKIKSERALGRRGATGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COAD_XANOM
Sequence: MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHANVEVRGFDTLLAHFVRQMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPSEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRESRAQA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y662_BACC2
Sequence: MNGIRDVVREEQPRERLLLEGAGSLSNRELLAVLLRTGSKEETVLKLSDKILHQFDGLRMLKDATLEELISIHGIGISKASQLMAAFELGRRMVRLEYQNRYSIRSPEDCAKYMMEEMRFLQQEHFVCLYLNTKNQVLHRQTIFIGSLNTSIVHPREVFKEAFRRAAASIICLHNHPSGDPTPSREDIEVTKRLVECGQIIGIEVLDHIIIGDHKFVSLKEKGHI
What are the official names of this protein?
UPF0758 protein BCG9842_B0662.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RL16_CHLL2
Sequence: MLMPKRVKYRKSQRGRMKGNSGRGTSVSFGSFGLKAMEPAWITSRQIEAARVAMNRYMKRDGKIWIRIFPDKPVSKKAAETRMGSGKGSPEFWVAVVKPGRIMFEAEGVSREVATEAFRLAAQKLPIKTKFIVRPDYEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: THIG_MYCTA
Sequence: MAESKLVIGDRSFASRLIMGTGGATNLAVLEQALIASGTELTTVAIRRVDADGGTGLLDLLNRLGITPLPNTAGSRSAAEAVLTAQLAREALNTNWVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPVVLDAGIGTASDAALAMELGCDAVLLASAVTRAADPPAMAAAMAAAVTAGYLARCAGRIPKRFWAQASSPAR
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXE12_ARATH
Sequence: MDSEIAVDCSPLLKIYKSGRIERLMGEATVPPSSEPQNGVVSKDVVYSADNNLSVRIYLPEKAAAETDSKLPLLVYFHGGGFIIETAFSPTYHTFLTTSVSASNCVAVSVDYRRAPEHPISVPFDDSWTALKWVFTHITGSGQEDWLNKHADFSRVFLSGDSAGANIVHHMAMRAAKEKLSPGLNDTGISGIILLHPYFWSKTPIDEKDTKDETLRMKIEAFWMMASPNSKDGTDDPLLNVVQSESVDLSGLGCGKVLVMVAEKDALVRQGWGYAAKLEKSGWKGEVEVVESEGEDHVFHLLKPECDNAIEVMHKFSGFIKGGN
What is the function of this protein?
Carboxylesterase acting on esters with varying acyl chain length.
What are the official names of this protein?
Probable carboxylesterase 12, AtCXE12.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: RPB9_ASFK5
Sequence: MKICKACSSCMVRTYVDGNIIFRCSCGESVQGDSQNLLVSSKVYHTGEMEDKYKIFIKNAPFDPTNCQIKKDCPNCHLDYLTQICIGSQKIIILVCRCGYTSNRG
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB9 homolog, RPB9 homolog.
What is the protein family that this protein belongs to?
Belongs to the Asfivirus DNA-directed RNA polymerase RPB9 homolog family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: DER_DEIDV
Sequence: MHKVAIVGRPNVGKSSLFNRLIGRREAVVADFPGVTRDAKEGLMLYHNHRITLVDTGGLWSGDEWEAAIREKAEWAMEGAQAVVFVLDPREGLSAADYEVADWLRRVGKPVIVVANKIDSPKHEVYLAELWGLGFGDPVAISAEHARGLDELLDRVMTHLPADDEDVPEVAPIRISLIGRPNVGKSSLLNAITNTDRAIVADQPGTTRDSLDVEWDFGGQRFVLVDTAGIRKKPDTAIEDYAIQRSQAAIQRSDLIWLVVNATDMGDHELKLANLAYESGKPVIVVVNKWDLVPDEELKRTEKDLNQKLHHISFAPRVYTSAINDYGIHEMLAEAMKLHDKWQSRIPTSELNRWLEVWQMRQAVPNFHGKKLKMYFMTQVETAPPTFAIFCNRADFVTRAYEGYLQNRIREDLQLAGVPVRLKWNEKGPYKRGKKDEDSED
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TX261_DICDI
Sequence: MFLSLLILLSYALGFVFCVVCLACGLYYFSELVEEHATVAKRWIKYTMWFVMGIIFLLGIFEDLDFTSLLFSFIGHCCYYTLLTEFPFVTLTGYKFILSVLSFIISHISWFIYFRNTENWYPFGEIIAIFTFCVWLIPLIFFISLAANDNSLPMANSYSSHSNSNIIGVDSEFTKKKSRISVLKSMFAWAKEKTSDITGQKSMKHYY
What are the official names of this protein?
Protein TEX261 homolog.
What is the protein family that this protein belongs to?
Belongs to the SVP26 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.