PharMolix/UniProtQA huggingface dataset:
Protein: TRHO_COREF
Sequence: MSIGKILLYYAFTPLSDPKAVQLWQRDLCESLNLRGRILISEHGINGTVGGDINDCKAYIRKTREYPGFAKMEFKWSEGGAEDFPKLSVKVRDEIVAFGAPNEIKVDENGIIGGGVHLKPEEVNQLVEERGDEVVFFDGRNAMEAQIGKFRDAVVPDVNTTHDFIKEIESGKYDDLKDKPVVTYCTGGIRCEILSSLMINRGFQEVYQIDGGIVRYGEKFGNQGLWEGSLYVFDKRMHMEFGEDYKRLGHCIHCDTPTNKFEHCVNEDECRQLVLMCPDCYANVETRHCGQDDCVEIAADLAARGVDPLVTQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ATP6_NITEU
Sequence: MSSEAELNPTTYIQHHLTNHTISVGDGAFWVLHTDTLFMSVLLGVVSLGLIWMVVRKATSGVPSKTQAFVELLIEFIDDQVKTTFHGNRHAFVAPAALTIFVWVLLLNAMDFLPIDIMAWIYEHIFGLHNWRSVPTADVNTTFALALSIWILTIYFAIKVKGFGGWVTELVCTPFGKNPLLWPFNLLLNVIEYISKPLSHSLRLFGNMYAGEIIFMLLGMWAATGVTGTFFGAILGAGWAIFHILIVVLQAFIFMMLAVVYLSMAHESH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEXA_EXISA
Sequence: MKKMSARQQQILDFIKDEVRAKGYPPSVREIGEAVGLASSSTVHGHLDRLEKRGLIRRDKTKPRAIEILTDDMPTMEEQESVMYVPVIGKVTAGTPITAIENVEEHFPLPAHIVGSDNVYMLSVSGDSMINAGILDGDRVLVRQQSTADNGEIVVAMTEEGEATVKRIYKEASKVRLQPENDELEAMYFDNVSILGKVIGVYRTIH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: FB171_ARATH
Sequence: MMKKRNTVYLSEDLIVEILSRVSAVSLARLRTTSKRWNALVKDERLAKKHSAYAPRQSLVITLIDSRVYLMNVSLQYGIEKVDLSAKLTGQFSLKDPLSNSLEEVDIRNVFHCDGLLLCSTKDNRLVVWNPCSGETRWIQPRSSYKVSDIYALGYDNTSSCHKILRMDRSEDRIPIQTEYQVYDFTSKSWLVDGVAGGLFIPSIGTRRRGLSVKGNTYWLALTEDGPPFDMFLLCFDFSTDGFRRLSLPTDTPCTYYDVSLSVTREEQQLCMFKSHGSELWIATKMESTGAISWSKSHRFHFRIDEMTVLADQEKPVFVYRFKPKSNMLHIVGEHIYIIQVDQHSADSKCPYLLTYVPSLVQIQQSI
What are the official names of this protein?
Putative F-box protein At3g21130.
Protein: PEX1_ARTOA
Sequence: MASSQRRGPTTKTPAVVGLTALRNCLVNLPSGLVSVLVSSNTPAQNVVVELSWRVKAPPQAGPLTGPATITRQAFAGWTGMPSKRQPLQPQGAGSFPGSQRSNSLEGCVEIDSAFARNVGLTEGSKVNILLHVDPPTTHTIHIEPLTASDWEIIELHATFLELNLLSQIRAITFAHPLTVYLSPTSTASIKVARIEPEDAASAFGFAKIAPNAEVIVAPKTRQRRMSHQGKSVKAKSLASTRHGKRRDDGSGPSGGGPVFFRAISLPHESFDAAEEQKGAYCVYLDPEVLAIPALRGCAFVGVVVVRPPGLAPPPDANQANNDVGGSTSPDAPEVIKPSLKIVAKLLPWKNAPDLKHIAISNLLADALDIKNVVGCVIRIEAAHQQLPKGSTTKVIIRPYSAGTLSSSAASEQSSLRWSGKDWKSDLAVRRVKEVLSQKTVWGEDILGGPLSDRLVLPAIPDSPLFAGGILLLDGSEVKHGWILGGDRKYILELGSEITTSRPHVPLSISETALPVLPPGRIVGVDKAINTASNILTRSASVLLTGARGSGKTSLVSVITSILKKKHFFHVLPISCAKFADERLQTIKDTFSRAIAEAKWFSPTVIVFDDLDRLIPAEVEHADSTRSRYIAEAFGKAIRDLKSSVLGPGNVVILATVQAKESVNSLIVGGHIFREIITLKAPNKAGRRQVLEQAVGGLSDEKSSPDTSSIRVKNPAALTNGPEPTLKIEKGLELLDIAGMTDGYMPADLQLLVGRARHEAIVRAVESGSDDAEADLVLGKKDFDKAIKGFVPAGLRGVKLQTSGAAWKDIGGLTETRKILLETLEWPTRYAPIFANCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSLLCDLPNLEDRVDILRALSLKLKIEESIGLEDIANLTEGYSGADLQAVLYNAHLEAIHDVIASQDEEVERFGNGGKGKGKVDAGSGNDSIDYISFSMGNKDSTGEPSTQPLTNGTQAARTKFAERAAVMAKLDKLKKIVQGDAAKQVQQQQSQTNQAQEEEKGDDEPVINWKHLQSSLKSTRPSIAPDERKRLFRIYNEFIVGRSGEMPSGQSSTEIGGRSSLM
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (By similarity).  Regulates autophagy and biogenesis of peroxisomes and Woronin bodies (PubMed:35323036).  Plays important roles in mycelial growth and development and stress response (PubMed:35323036).  Is also essential for conidiation and fatty acid utilization (PubMed:35323036).  Required for nematode predation via trap formation (PubMed:35323036).
What are the official names of this protein?
Peroxisomal ATPase PEX1, Peroxin-1, Peroxisomal biogenesis factor 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Shuttles between the cytoplasm and the peroxisomal membrane.
Protein: COAT_BMDV
Sequence: MDSSEVVKVKQASIPAPGSILSQPNTEQSPAIVLPFQFEATTFGTAETAAQVSLQTADPITKLTAPYRHAQIVECKAILTPTDLAVSNPLTVYLAWVPANSPATPTQILKLRVYGGQSFVLGGAISAAKTIEVPLNLDSVNRMLKDSVTYTDTPKLLAYSRAPTNPSKIPTASIQISGRIRLSKPMLIAN
What are the official names of this protein?
Coat protein, Virion protein.
What is the protein family that this protein belongs to?
Belongs to the tymoviruses coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: BXL2_ARATH
Sequence: MILHKMAFLAVILFFLISSSSVCVHSRETFACDTKDAATATLRFCQLSVPIPERVRDLIGRLTLAEKVSLLGNTAAAIPRLGIKGYEWWSEALHGVSNVGPGTKFGGVYPAATSFPQVITTVASFNASLWESIGRVVSNEARAMYNGGVGGLTYWSPNVNILRDPRWGRGQETPGEDPVVAGKYAASYVRGLQGNDRSRLKVAACCKHFTAYDLDNWNGVDRFHFNAKVSKQDIEDTFDVPFRMCVKEGNVASIMCSYNQVNGVPTCADPNLLKKTIRNQWGLNGYIVSDCDSVGVLYDTQHYTGTPEEAAADSIKAGLDLDCGPFLGAHTIDAVKKNLLRESDVDNALINTLTVQMRLGMFDGDIAAQPYGHLGPAHVCTPVHKGLALEAAQQGIVLLKNHGSSLPLSSQRHRTVAVIGPNSDATVTMIGNYAGVACGYTSPVQGITGYARTIHQKGCVDVHCMDDRLFDAAVEAARGADATVLVMGLDQSIEAEFKDRNSLLLPGKQQELVSRVAKAAKGPVILVLMSGGPIDISFAEKDRKIPAIVWAGYPGQEGGTAIADILFGSANPGGKLPMTWYPQDYLTNLPMTEMSMRPVHSKRIPGRTYRFYDGPVVYPFGHGLSYTRFTHNIADAPKVIPIAVRGRNGTVSGKSIRVTHARCDRLSLGVHVEVTNVGSRDGTHTMLVFSAPPGGEWAPKKQLVAFERVHVAVGEKKRVQVNIHVCKYLSVVDRAGNRRIPIGDHGIHIGDESHTVSLQASTLGVIKS
What is the function of this protein?
May be involved in remodeling of xylans during vascular development.
What are the official names of this protein?
Probable beta-D-xylosidase 2, AtBXL2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: KCNH2_PIG
Sequence: LLKETEEGSQAPDCGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTAR
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel.  Channel properties are modulated by cAMP and subunit assembly.  Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 2, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, Voltage-gated potassium channel subunit Kv11.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL30_NATTJ
Sequence: MADKKLKVTLKRGLIGVSDGKIRTIKALGLKKRSHSVIKNDTPEIRGMIDKVSNLVEVEELEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RS17_YERPA
Sequence: MTDQIRTLQGRVVSDKMEKSMVVAIERVVKHPIYGKFIRRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAIL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: IF2_CORU7
Sequence: MAGKLRVHELAKKLGVTSKELLATLKEQGEFVKTASSTVEPPVVKKMKQFYGVAQESKPTTPPSPLAQAGSVPDSTQRGPKPGAKPAAKPEAAPKPGTAAAKPSAKPSPAAAAKAAPAAKATPTPAEAAPKPGQAAAKPAAKPGQKPARAAGKPGPKPGPKPGARPQRVANNPFSSTTERPPRPRGGATPGDMPRPGGTRGGAGRGQAPRPGARPAQGQGRGQGTAKPGAARQGGGRRPSPAMMPATPSPGQMPAKSAAGFGGGRGRGGRPGGPGGPGGPGGPGPRGGRGGRRGGTAGAFGRPGGPPRRGRKSKRQKRNEYEAMQAPKVVGGVKLPSGNGEKIRLARGASLADFADKINADAAALVQALFNLGEMVTATQSVSDETLQLLGDEMDYKVEVVSPEDEDRELLESFDLQFGEDEGDDEDLAQRPPVVTVMGHVDHGKTRLLDTIRKENVGSGEAGGITQHIGAYQVSVNMEGVERPVTFLDTPGHEAFTAMRARGAKSTDIAILVVAADDGVMPQTVEAINHAKAAEVPVVVAVNKIDKPTAQPDKIRGQLTEYGLVPEEYGGDTMFVDISAKQGQNIDQLLEAVLLTADASLDLRANPDMDAQGIAIEAHLDRGRGPVATIIVQRGTLRVGDSIVVGDAYGRVRRMIDEHGNDVQEAGPSRPVQVLGLTSVSGAGDNLLVVDEDRTARQIADRRDARRRNALAARSRKRVSLEDLDEVLKETSTLNLILKGDNAGTVEALEDALLKIEVDDEVALNIIDRGVGAVTETNVHLAAASDAVIIGFNVRSEGKATEAANAEGVDIRYYSIIYKAIEEIEAALKGMLKPIYEEKEIGTAEIRQIFKASAVGLIAGCMVETGKVRRNAKVRLVRDGKVISEDATIDSLRREKDDVTEVSHGYECGMVLSYPNIEVGDRIEAYEMVEVPRD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THRB_PIG
Sequence: MAHVGGLWLHGCLALAVLVSLVHSQHVFMAPQQALSLLQRARRANSGFFEEMRKGNLERECVEEQCSREEAYEALESPSETDAFWAKYTACESVRKSREKLVECLEGNCAEGLGMNYRGNISVTRSGIECQLWRSRYPHKPEVNSTMYPGADLRENFCRNPDGSITGPWCYTTSPTVRREACSIPVCGQGRVTAELIPRSGGSTVNVSPPLETCVPERGRQYQGRLAVTSHGSPCLAWGSSQAKALSKDQDFNPAVPLVENFCRNPDGDQEGAWCYVAGQPGDFEYCDLDYCEEPVDEEVGDALGENADAAIEGRTTADDFQPFFNEKTFGAGEADCGLRPLFEKSSLEDKTEKELFESYIEGRIVEGSDAEIGLAPWQVMIFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALLKLRKPITFSDYIHPVCLPDKETATKLLRAGYKGRVTGWGNLKETWTTSASEVQPSVLQVVNLPIVERLVCKASTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWMQKVIDRFGG
What is the function of this protein?
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.  Functions in blood homeostasis, inflammation and wound healing (By similarity).
What are the official names of this protein?
Prothrombin, Coagulation factor II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: LIPB_RUBXD
Sequence: MELEERRAALDVRRLPGLTPYAEAWELQRELVRKRRSGEIPDTLLLLEHPPVYTVGRAARDASNLGAGEEYLRSLGAEVFWSDRGGDATFHGPGQLVGYPIIRLKVRDTHRYLRDLEEVVIRALAGYGLEGRRHPRYTGVWVNGSKICAIGVKFSSGWIASHGFALNVNTDLSWFDRITPCGIREYGVTSLERELGREIPLAGVEREIVSGFREVLGDPGS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKB70_PINPS
Sequence: XGESWETPETGDEVE
What is the function of this protein?
PPIases accelerate the folding of proteins during protein synthesis.
What are the official names of this protein?
70 kDa peptidyl-prolyl isomerase, Cyclophilin, PPIase, Peptidyl-prolyl cis-trans isomerase, S1205-06.
Protein: TRUD_GEOSL
Sequence: MARDEHDSRYLTAELPGTGGLFKETPEDFLVEEISLYLPCGEGEHTYAVIEKRGITTLEAIRRLCRATGAPERDTGYAGMKDARGITRQTVSLPRVTPAEVMGLNIPGIRILSADRHRNKLRLGHLAGNRFRLRLRETVPDAADRARAILDVLARRGVPNRFGEQRYGIQGNSHLVGRAMLAGDWRGAVDLLMGDPAKVEGERWRAAIEAYRQGDLAGSLSLFPGHCRTERDVLQRLAKRPDDFERAVHGVHPRLKKLYLSACQSALFDRVLETRLQTIDHVMEGDLAWKHDNGACFLVTDAKAEAPRAERFEISPTGPLFGCRMTSPEGEPAALEKSILDAAGLTPAAFNLAGGLRMEGERRPLRVPLEGPELSCEEEDLVLRFSLPRGSYATAVLREVMKRPGNGA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: UBIG_CERS5
Sequence: MSATSTIDPAEVAKFEAMAAEWWNPHGKFKPLHQMNPCRLDYITEQIAAEFDRDLSAPLPFQGLRLLDIGCGGGLLSEPMARLGADVVGADAAPRNIPVARLHAEQSGLTIDYRNTTAEDLAAAGERFDVVLNMEVVEHVADPLAYLTACRELLKPGGLMVCSTLNRNPKSFAMAIVGAEWIMRWLPKGTHDWSKFITPDELYDLIRKAGLDPVDRKGMVFNPVSWSWSLSDRDLSVNYVTASVRPR
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: YCF43_PORPU
Sequence: MSLEPQNNLLANINTNSENLPENDVPMSITEHLEELRQRTVFVFIFFLLAATISFTQIKIIVEIFQAPAIGIKFLQLAPGEYFFSSIKIAIYCGIVATTPFGVYQVILYILPGLTNKERKVILPILIGSIVLFIVGGIFAYFVLAPAALNFLISYGADIVEPLWSFEQYFDFILLLLFSTGLAFEIPIIQLLLGISGTVSASQMLLAWRYIIIISTIIGAVLTPSTDPVTQIIMSSAVLALYFSGVIILFLLRK
What are the official names of this protein?
Uncharacterized tatC-like protein ycf43.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: NAC_METVS
Sequence: MFPGGKMNPRMMKQMQKMMKDFGMDSEDLKAVKVTIELEDKIMVFDKPKVQVMDMMGTKTYTISGRSKNTSKTAEKIEDTEVKVEVTEEDIEMVATQCNVSKEEAKTALEDVNGDLAEAILKLGN
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: ICAM5_HUMAN
Sequence: MPGPSPGLRRALLGLWAALGLGLFGLSAVSQEPFWADLQPRVAFVERGGSLWLNCSTNCPRPERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDRVELMPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGAQELIRRSFAGEPPRARGAVLTATVLARREDHGANFSCRAELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPRLLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASAEQEGARQLVCNVTLGGENRETRENVTIYSFPAPLLTLSEPSVSEGQMVTVTCAAGAQALVTLEGVPAAVPGQPAQLQLNATENDDRRSFFCDATLDVDGETLIKNRSAELRVLYAPRLDDSDCPRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGGAVLALGLLGPVTRALSGTYRCKAANDQGEAVKDVTLTVEYAPALDSVGCPERITWLEGTEASLSCVAHGVPPPDVICVRSGELGAVIEGLLRVAREHAGTYRCEATNPRGSAAKNVAVTVEYGPRFEEPSCPSNWTWVEGSGRLFSCEVDGKPQPSVKCVGSGGATEGVLLPLAPPDPSPRAPRIPRVLAPGIYVCNATNRHGSVAKTVVVSAESPPEMDESTCPSHQTWLEGAEASALACAARGRPSPGVRCSREGIPWPEQQRVSREDAGTYHCVATNAHGTDSRTVTVGVEYRPVVAELAASPPGGVRPGGNFTLTCRAEAWPPAQISWRAPPGALNIGLSSNNSTLSVAGAMGSHGGEYECAATNAHGRHARRITVRVAGPWLWVAVGGAAGGAALLAAGAGLAFYVQSTACKKGEYNVQEAESSGEAVCLNGAGGGAGGAAGAEGGPEAAGGAAESPAEGEVFAIQLTSA
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
What are the official names of this protein?
Intercellular adhesion molecule 5, ICAM-5, Telencephalin.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UNG_BACC2
Sequence: MENVLRNDWGPLLAPEFEKEYYLTLSSFLTEEYSTHVVYPKVEDIFNALQYTSYENTKVVILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYEIPNNGYLVKWAEQGVLLLNTVLTVRQSEANSHKGKGWEHFTDRVIQLLNEREKPVIFILWGRHAQAKKKLITNPNHHIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEREIDWEIPNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAXB1_XENTR
Sequence: MSALQEIPSPISNMQTSNFAHVIFQNVAKSYLPNAPLECHYTLTQYIHPHPKDWVGIFKVGWSTPRDYFTFLWSLMPEKYVAESTCNCVLTFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRASSPVDELLTMEDEGHSDMLVVTTKTGLLELKIEKTMKEKEELVKITTVLEKEVLQLREHVEGLESEFLREQKRSEQLSSEREELFNASEILRNESDEAKRKCKEMSAKIIQLEEDIMLVTQKAIAKETELDSLKDKLKKVVLEKDQLECQLKYEKDEKDLYKVHLKNTEIENTKLLTEVQTLKNLDTNKENLISHYKEELGKLQICLADKEKMNKELLQNSSNKEDIAFLKQQLRKLEDQHQASRQEVSLMSRELSEAVNKRDKTMADLHSARLDTDSVRMQLADALAQLSMRDEQQQKSNPFAKKDQGADNNRVEQELRKEVEDLKLRLQMAADHYKDKFKECQKLQKQVVKLTEQLKATENQQKERELFCATEAAAVTVMKQCTPPVSPFTSDSLPEFDIREQVREMSLEMAEKTEKYRKCKQMLAEEKARCSAYADDVAKMELKWKEQLKVNDSIKRQLIALDDQYKVQSAEKDREICDLSYSIETLRNEKAKMERFINDLEKKLEKQAGWAASNTQGLQFFNPYCDEHRLAPAIPAQQPLLQFGNPYASQETRDGADGAFNPDEVQGPPVRATSWGLEDKVVCSQPARNLSRPDGLEDPDENNAGLITKDEDDDDDDDNVNFEQTPDPTRIAMHDQSGFCFEAGYTMNKKCPLCPVSFPPNYDQGQFEAHVESHWKVCPMCNEQFPPDCDQQIFERHVQTHFDGSVLNFD
What is the function of this protein?
May have an anti-apoptotic activity.
What are the official names of this protein?
Tax1-binding protein 1 homolog.
Protein: RL27_ACIB3
Sequence: MATKKAGGSTKNGRDSNPKMLGVKVYGGQTVTAGNIIVRQRGTEFHAGANVGMGRDHTLFATADGVVKFEVKGQFGRRYVKVETV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GPMA_STRPZ
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAMPYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GREA_CHLAD
Sequence: MTEKPTYLTREGRARLEAELEHLMTVERKQIAERIAAAKELGDISESGEYEDAKKAQALLEGRIRELKHLLSRAEIIDEDQASTGEVRIGSSVTVRFEDDGSEETWTIVGSAEANPRQGRISNESPIGAALLGKRVRNKVTVHTPSGVMKLTILKVR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TBB4A_MACFA
Sequence: MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-4A chain, Tubulin beta-4 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL22_MESHJ
Sequence: MKVENHNLAVASLKTQRISAFKARLVAVLLKGKKVSDALAILSHTKKKASPIFTKLINSAVANAINNHGFEHSNLIIKAAIVNEGPTLKRFRPRAKGAASQILKRTSHFKVILASQNGGESQNQEYQETEKNLVSKSPENTQSGALSQQSQAEQPQNDPENGVDSQLSAKTNSITTAKKTDLADNNTKNDATNTVLAQEKEVK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RUVC_SALPB
Sequence: MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRMR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CLPX_XANOR
Sequence: MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFDMEGVELEFRADALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPAPAKAASGD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.