PharMolix/UniProtQA huggingface dataset:
Protein: RBSKI_FRUSL
Sequence: MKKIIVVGSTNVDKVLNVEKYALPGETLAINTYQQSHGGGKGANQAIAAARSGADTTFITKLGNDEDAKMMVKGFKADGMNIDDVITTTDQETGKAYITVDKSGQNSIYVYGGANMAMTPTDVDAHKSAIINADRVIAQLEIPVPAVIEAFKIAKEHGVQTILNPAPAKELPEELLKLTDIITPNESEAATLTGIEVKDETSMLANAKFFFERGIKMVIITVGGRGSFFATPDDHALIPPFPAKVVDTTAAGDTFIGSLASQLEIDLSNIRKAMLYASHASSLTIQVAGAQNSIPTREAILNVINQDQMTKTEIEKQKAQAAAYAAKLVPDHIVLGLGSGTTAAYFVKAINQRINDEHLDIQCVATSVGTEKLAEKLGMRMLDVNTIDQVDLTVDGADVVDHQLNGIKGGGAALLFEKLVADMSKQNIWIVDQSKYTDSLAGHILTIEVIPFGGMGVFRYLKENGYQPEFRFKDNGDILETDSGNYLINIIIPKDADLEKLSIDLKKQTGVVEHGLFLNVCDELIIGGDQIKTIKRSDLS
What is the function of this protein?
Bifunctional enzyme that catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium, and the reversible conversion of ribose 5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Bifunctional ribokinase/ribose-5-phosphate isomerase A.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ribose 5-phosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPA_DEBHA
Sequence: MSENTITFVTGNANKLKEVIAILSTSESQDGMSKVGKYSITNKSLDLDEIQGTIEEVTINKAKAAANILKGPVLVEDTCLGFEAFNNLPGPYIKWFVKSIGLSGLVDMLYKFENKGANAICTFGYCEGPNAEVKLFQGVTKGNIVDSRGPTDFGWDSVFEPEGFDQTYAEMDKKNKNTISHRFRALDKLRDFLTNQ
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL11_ANADF
Sequence: MKKVTGQIKLQLPAGKANPAPPVGPALGQHGVNIMEFCKQFNAATQAQAKEALIIPVIITVYQDRSFTFQLKTPPAAILLKKAAGLHTEKKKGSGAHKPGKEKVGQVTRKQVEQIAKTKMQDMTAGSLEAAMRTVEGTALSMGIDVVG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CARB_SULIL
Sequence: MKETPKKVLVIGSGPIKIAEAAEFDYSGSQALKALKEEGIETVLVNSNVATVQTSKKFADKLYMLPVVWWAVEKVIEKERPDGIMIGFGGQTALNVGVDLHKKGVLQKYGVKVLGTQIDGIEKALSREKFRETMIENNLPVPPSLSARSEEEAIKNAKIVGYPVMVRVSFNLGGRGSMVAWTEEDLKKNIRRALSQSYIGEVLIEKYLYHWIELEYEVMRDKKGNSSVIACIENLDPMGVHTGESTVVAPCQTLDNLEYQNMRTYTIEVARSINLIGECNVQFALNPRGYEYYIIETNPRMSRSSALASKATGYPLAYVSAKLALGYELHEVINKVSGRTCACFEPSLDYIVTKIPRWDLSKFENVDQSLATEMMSVGEVMSIGRSFEESLQKAVRMLDIGEPGVVGGKIYEAKMSKVEALKYLKERRPYWFLYVAKAFKEGATIDEVYEVTGISKFFLNKIKGLVDFYETLKILKEIDEETLKLAKKLGFSDEQISKALNKSTQYVRKIRDQSNIIPVVKLIDTLAGEWPSVTNYMYLTYNGTEDDLEFSQGNKLLIVGAGGFRIGVSVEFDWSVVSLMEAASKYFDEVAVLNYNPETVSTDWDIARKLYFDEINVERVLDLIKKEKFRYVATFSGGQIGNSIAKELEENGVRLLGTSGSSVDIAENREKFSKLLDKLGISQPNWVSATSLEEIKKFVNEVGFPVLVRPSYVLSGSSMKIAYSEEELYEYVRRATEISPKYPVVISKYIENAIEAEVDGVSDGNRVLGITLEHVEEAGVHSGDATMSIPFRKLSENSVNKMRENVLSLARELNIKGPFNVQFVVKDNTPHIIELNLRASRSMPFSSKAKGINLINEAMKAIFNGLDFSEDYYEPPSKYWAVKSPQFSWSQLRGTYPFLGPEMKSTGEAASFGVTFYDALLKSWLSSIPNRIPNKNGIALVYGDKNLDYLKDTAVNLVKFGLTVYSISELPLQGIETIDKTKAEELVRAKKVEIVVTDGYLKKFDYNIRRTAVDYNIPVILNGRLGYEVSKAFLDYDSLTFFEISEYGGGI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MF127_ASPFN
Sequence: MKKIYNVYFLCGFATLGGGLFGFDISSMSGVLGTAAYTNYFQVGSGQYKQGSITCAMPFGSLVGALCSSFIADRYSRVRAIQFSSILWIIGSIFMCASNGIPLLVVGRVIAGGCVGIASAMVPVYQAEIAPKEIRGRVISLQQWAITWGILIQYFIQYGASNIDGGPNNPTQSTAAFRIPWGIQIVPGVILFFGMFLFPKSPRWLASKDRWEEALQVLSKLHGQGDVNHPKVLAEYKEIQEALALEREQSATGFQELIKPRIFKRVILGMSLQMWSQLCGMNVMMYYIVYIMQSTGAGSPLLTASIQYILNTALTLPAIIYLDKFGRRPAILIGFFLQAIFLYLEGGLQGGFGAPNPHTDPKLDAISWTVADHPAVGKAIIALSYLFVCSFATTIGPTSWTYPAEIYPAKVRAKAVSLATASNWIWNCLLALFVPPLLWSINWKMYMIFAAFNTAAFIHMFLTAPETKGYTLEEMDDVFDSGLPAWRKLERKSRMEELEKEIIEGNLKITPAHEATGVSATHVTPEKQV
What is the function of this protein?
Probable MFS glucose transporter; part of the gene cluster 27 that mediates the biosynthesis of asparasone A, a sclerotium-specific anthraquinone pigment important for sclerotial survival (PubMed:24412484).
What are the official names of this protein?
MFS glucose transporter mfs1, Asparasone A synthesis protein mfs1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACYP_DEHMB
Sequence: MHCLRAIVKGKVQGVYFRDFTRTQATRLGLCGYAKNLANGAEVEVVAEGDKDALLEFLNLLRSGPPRAEVKDVETGWETATANYSDFRIKH
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: PBO6_CAEEL
Sequence: MQCSFLTIFIFITTVTVGVAEFSEQYQGSSSRLTRHLLEKHNKCSPPDGRVDISHNIELVHIIGINELNQNMQVLVYIVQQWTDASLSWKVEEFRGIKHTWLPEHSIWIPDIIVFNTLEHKMLLEAVRSPIKVSYTGEVTYAYPAIYTVLCQIGIATFPFDDQVCKIRFASWAYDEDKILLNASHKPLLKNYSPNEEWALQDVDMARKEYEHEETVVSEIIYYIKVARKPFYYLISLVVPSYIICVLSIAGLFARFSTKHERQERFTLGVTAILSMAVLSLVVTEKVPHSSENVPLLIVYMHFIIVMVTIATILTSTVMRVHAKGFRTHFLSPPNWIRKVLLIARKHANFFQQHGKVYMDIHTTAEQWGEVSRRMDYLLASVFIIIISTPTLYLFYMCFQMDHATAERVLLENAKRRDQLYY
What is the function of this protein?
Forms a proton-gated ion channel with pbo-5 that is activated by acidification of the posterior coelomic space, leading to posterior body wall muscle contraction (pBoc) during the defecation cycle.  Not necessary for stimulation of posterior body contraction (pBoc).  Does not bind neurotransmitters such as acetylcholine, gamma-aminobutyric acid, glycine, serotonin, glutamate or choline.
What are the official names of this protein?
Proton-gated ion channel subunit pbo-6, PBoc defective protein pbo-6.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: SUMO1_ARATH
Sequence: MSANQEEDKKPGDGGAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVDMNSIAFLFDGRRLRAEQTPDELDMEDGDEIDAMLHQTGGSGGGATA
What is the function of this protein?
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer.  Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process.  Required for the massive protein sumoylation in the nucleus induced by heat shock and controlled by SIZ1.  Involved in the regulation of the heat stress transcription factor HSFA2 in acquired thermotolerance.
What are the official names of this protein?
Small ubiquitin-related modifier 1, AtSUMO1, Ubiquitin-like protein SMT3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RPOC_BARBK
Sequence: MNHEVMNLFNPQALAQIFDSIRISIASPENILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPGRISTLLDLTLKDIERILYFESYIVTEPGLTSLKLHQLLSEEEYMLAIDKFGEDQFTAMIGAEAIYDLLAGMELDKIANDLHAELAETTSELKQKKLIKRLKIVENFLESGNKPEWMIMKTIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIVRNEKRMVQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEHPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVSEKEPGEGMAFADMGELHHALENKVVTLHTKIKGRFKNIDKDGKEVAQLYDTTPGRLIIGELLPKNPNISFDIVNQEMTKKNLSKMIDQVYRHCGQKETVVFCDRIMQLGFSHACRAGISFGKDDMVIPESKSRLVAETEALVKEYEQQYDDGLITQGEKYNKVVDAWGKCTDRIADEMMKGIQAVKFDPKTGRQQRMNSIYMMSHSGARGSANQMRQLAGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISAVDCGTIKGLTMQPIIDAGQIVASLGQRILGRTALLDILHPVSGEVIIEGGTMIEEADVLKIEEARIQSVQIRSALTCETRLGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYFESSYEGIVELRNRNVVRNSEGHLVVMGRNMAVLIKDENGKERAVHRISYGARLFVDDGDIIKRGQRIAEWDPYTRPILTEVDGYVGFEDMVDGLSVTETTDESTGITKRQVIDWRVNPRGADLKPAMIIHSDKQGKNIAKLHKGGEARYVMSVETILSVEPGSHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAIIAEISGTVRFGRGYKNKRRIIIEPNDETLEPVEYLIPKGKLFHLQEGDKIEKGDYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDSDYIPGDNVDRIELDEINDHLIAEGKKPASGTPILLGITKASLQTPSFISAASFQETTRVLTEAAVSGKIDTLQGLKENVIVGRLIPAGTGGTIAQIRRIATVRDDLIVDEQRKSSNDGISKAMLTDMTANAAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: FLGA_AQUAE
Sequence: MSSTPREYRRRMKCSLKRLIYAVNFLFFLFTFSLDLESLIKNELRKEFGEEVRLKNYKVLTGIPDNFSKVELKVYKNSPRGFLHLKNTKVGTIALELEWKCRVLVAKRDIYPGERLNFSNVEEREIYLERCPQNFKENFVNFVALKEIKKGTIVRRSYLKKEFLVKRGEIVNAVYENGNVVIRFRTKALENGYYGEVIRVLSPFSRKVIRGKIIGEGTVKILR
What is the function of this protein?
Involved in the assembly process of the P-ring formation.  It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly (By similarity).
What are the official names of this protein?
Flagella basal body P-ring formation protein FlgA.
What is the protein family that this protein belongs to?
Belongs to the FlgA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RSMJ_DECAR
Sequence: MGPAFASAALALSEALNLPSSGEADFVLQVGTEGLQLQELGPHAPGPLSVDFVRGPLAHRRLQGGGSGQMIAKAVGIQPGVRPDVLDATAGLGRDAFVLAQLGCNVRLIERHPVIAALLADGLQRARLDPDVRPIIERMHLQTGDAIQLMNAWEGDPPQVIYVDPMFPHREKSSLVKKEMSMLRPLVGDDLDASSLLEAALKLATHRVVVKRPRKAPSVLGPKVGYVLEGKSSRFDIYPKRSLKP
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH1_BACHK
Sequence: MEMRNVKGTKDYLPEEQVLRNKIKRACEDTFERYGCKPLETPTLNMYELMSYKYGGGDEILKEIYTLQDQGKRDLALRYDLTIPFAKVVAMNPNIRLPFKRYEIGKVFRDGPIKQGRFREFIQCDVDIVGVESVMAEAELMSMAFELFQTLNLEVTIQYNNRKLLNGILQAIHIPTELTSDVILSLDKIEKIGIDGVRKDVLERGISEEMADTICNTVLSCLQLSIADFEEAFNNPLVADGVNELQQLQQYLIALGINENTIFNPFLARGLTMYTGTVYEIFLKDGSITSSIGSGGRYDNIIGAFRGDNMNYPTVGISFGLDVIYTALSQKETVSSTADVFIIPLGTELQCLQIAQQLRSTTSLKIELELAGRKLKRALNYANKENIPYVLIIGEEEICTETVMLRNMKEGSEVKVPLSSLSNYL
What are the official names of this protein?
Histidine--tRNA ligase 1, Histidyl-tRNA synthetase 1, HisRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_BUCAT
Sequence: MSYNYFGKKILILGMGLTGISCINFFLKKGIKPKIIDESKHPSNFIKIPQNIEYSLGSLDHQWILESDLIVISPGISSFKPILIKARLLGIEIISDIELFSREVTCPIISITGTNGKSTVATMIEKIAKKSGYKAFLGGNIGVPVLEILDKEADLYIIELSSFQLENTFNLKSKIAVILNISEDHINRYPNGFQQYKNTKLSVYNQAEICIINSNDKIEKSLIHSKNKKWISFGTNRSDYRICSKSNDPILFFKNKKILNTSEILLYGYHNYNNILVSLAISDAMQFPRNDAINVLKSFSNLPHRFQIIKNEKGVRWINDSKSTNVNSTQVALNSIKTTGTIRLLLGGDSKSANFNILKNIFRTLKIKIYCFGRDGIKLSKICEKKSIYVENLKKAVILISKQVKSGDTVLLSPGCSSLDQFSNFEERGNLFIKLIKEIT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATGT_METBF
Sequence: MSAIFEILDKDAGGRIGRLRTPHGTVETPTVMPVINPNIQLIPPKEMRNFGAEILITNSYIIYRKEELKSVALEKGLHGLLGFDGPIMTDSGSFQLSVYGSVEVTNEEILGFQQKIGSDIIVPLDIPTPPDVHYRRAEEELAITAERLEAARKFIQSEQLLAGPVQGSTYPELREKAASHLKDLNFEVYPLGAVVPLMEAYRYAELVDVIAASKKGLSPASPVHLFGAGHPMMFALAVAMGCDLFDSAAYALYAKDGRYITVNGTYHVEKLNYLPCSCPVCSKYTAEELKKADNREELLGKHNLYATFAEIRLIKQCIKDGKLLELVEQRCRAHPKLLDGLKKLYTHSSWLEQLDPATKGTFFYCGPESSSRPEILRFGKRLDRFSLQGSVIIRTGSVKGEKDYDQILTFKAPFGAFPVEMEEVYPFNAEVPKFPDYESLNTALSNTLKLIDLNPEAEFTFICEEEFKHPLIEEIRKRAKLVYRKDWKKE
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: ATPG_HELMI
Sequence: MPGMRDIKRRIRSIKSTQQITKAMKMVAAAKLRKAQEKVIQARPYAKRIQGVLSRLVAAASDVNHPLLTTREVKRVGYVVITADRGLCGGYNANIIRKVNNEIKGRDDVSLVCVGRKSRDFFKRMGKRIEADYVGLGEDISFGMAKEIAAKVMELYEQGTVDQVQLVFTEFYSALTQKPVQMQLLPIPAQAGESANSAKDSKGPQPLYAFEPSPEAVLDELLPKYVENQIYRALLESKASEQGARMTAMGSATDNAKEMINKLTLSFNRARQAAITKEISEVVGGAAALG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EME1_HUMAN
Sequence: MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVKSVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
What is the function of this protein?
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication forks.
What are the official names of this protein?
Crossover junction endonuclease EME1, MMS4 homolog, hMMS4.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
Protein: ISPE_CARHZ
Sequence: MLIFAPAKINLTLDILGKRPDGYHELWSVMQAITLGDLVEIEPAEGINLRVVGADLPVDSTNIAFKAVQALRAATGKAIGASITIRKKIPLEAGLAGGSADGAAVLYGLNKLYNLNLSQEELLEIGAKISADIPFCLTGGTALVQGIGEKVKKLPPLKKGYFVIYKPPFGISTKEAYLRLAGKDLTKEHPDREKILKALGKENLEDLGKFLKNLLEISALEINPEIYKYKNELLNLKPLGVLMSGSGSALFALTENLKKAKEIYYQLTLPGQKFIVRPYAAGPTCLKL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: COX7C_MOUSE
Sequence: MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWRLLAMMTVYFGSGFAAPFFIVRHQLLKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SECA_PROM2
Sequence: MLKLLFGDPNTRKLKRYQPIVEEINFLEEEISQLTDDDLRKETQNLKSKISSELDFKKQKELLEEFLPKAFAIVREASKRVLDMRHFDVQLIGGMVLHECQIAEMKTGEGKTLVATLPCYLNALTGKGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQDMNPVERKKNYDCDITYATNSELGFDYLRDNMATDVNEVVQRKFNYCVIDEVDSILIDEARTPLIISGQVERPQEKYQKAAQLSLKLVKAKELSKDGIDPEGDYEVDEKQRSCILTDQGFAKCEEYLGVNDLYNPKDPWAHYITNALKAKELFIKDVNYIIKNNEAVIVDEFTGRVMPGRRWSDGQHQAIEAKESLQIQPETQTLASITYQNFFLLYPGLAGMTGTAKTEEVEFEKTYKLESTVIPTNQLRKRKDWSDQVFKTEIGKWKAVAKETANIHRDGRPVLVGTTSVEKSELLSSLLSEEKIPHNLLNAKPENVEREAEIVAQAGRAGAVTIATNMAGRGTDIILGGNSDYMARLKLKEILIPLLVKPDNEHKPPIPKQRNSKSKGGFSKKASSKLKKNISNSSTSLFPCKLDEAIEKQLSLLSDELVKNWGDRQLSVLELDDRIATAAEKAPTDDDLIKLLRESLSAVKKEYEKVLTHEEEKVRKAGGLHVIGTERHESRRVDNQLRGRAGRQGDLGSTRFFLSLEDNLLRIFGGDRVANLMNAFRVDEDMPIESGMLTRSLESAQKKVETYYYDIRKQVFEYDEVMNNQRKAVYGERLRVLKGNDLKRQVIGYGERTMSEIVDAYINPDLPPEEWNIDQLISKVKEFIYLLDDLKSEDINLLSIEELKNYLQEQLRIAYDLKESQIEKIRPGLMREAERFFILQQIDNLWREHLQSMDSLRESVGLRGYGQKDPLIEYKNEGYDMFLEMMTNMRRNVIYSMFMFQPKTEVNEKK
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: FWDC_METWO
Sequence: MSEIILTPKEQPEVPLEAPNIKPDVFAGKSIDEIKNIQIMHGNEVVKLGDFFEVSGEPADAPEDIKIIIDGDVYNTKRIGQEMTAGEIIVRGNVNMYVGAGMKGGKITVEGNAGSWAGQDMRGGEIEILGDADDYVGSSYRGDWRGMSGGTITVHGNADNEIGEYMNGGKIIIKGDVNIMPGIHMNNGLIIIEGNVVARAGGEMAGGTIVVKGMMQEFLAGFKYLGVEKDIELMVKNSPGAFYKFEGDHAIKGAKGIVYAAVGCNGHIAP
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  This enzyme is oxygen-labile.
What are the official names of this protein?
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C, Tungsten-containing formylmethanofuran dehydrogenase II subunit C.
What is the protein family that this protein belongs to?
Belongs to the FwdC/FmdC family.
Protein: DUSTY_PANTR
Sequence: MEGDGVPWGSEPVSGPGPGGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHNHTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQDCNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAHQGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDLVNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTKRMESERSLLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAKALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMDRLCKSNSEQPNRGLDDST
What is the function of this protein?
Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation.  Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death.  In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
What are the official names of this protein?
Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, Receptor-interacting serine/threonine-protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction. Note=Detected in basolateral and apical membranes of all tubular epithelia. Detected at apical cell-cell junctions. Colocalized with FGF receptors to the cell membrane.
Protein: RL23_AERS4
Sequence: MIREERLLKVLKAPHISEKSTMVAEKQNTIVFKIAVDATKAEVKAAVAKLFEVEVETVRTLNMKGKTKRSGARVGRRSDWKKAYVTLKAGQDIDFMGAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ECFA2_LACPL
Sequence: MAITFKQVDFTYQPGTPFETKALTDINVTIPTGSYTALIGHTGSGKSTLLQHLNALLKPTSGTVTIGERVITPTTSNKDLKRLRQHVGIVFQFPESQLFEETVAKDIAFGPQNFGASEADALKTAAEMLALVGLDESLLTRSPFDLSGGQMRRVAIAGVLAMQPQVLVLDEPTAGLDPQGRLDMMEMFARLRHERDLTVVLVTHQMDDVANYADNVIVMDRGQIVKTGTPREIFKDPAWLTAHQLGLPKTTAFAHTLQKQGWQFNEWPLTEDELAAAIVQQLPPNAMGEVAAHDE
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.