PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_NEIG1
Sequence: MSSSVSSKTRYWVLALAAIVLDQWSKWAVLSSFQYRERVNVIPSFFDLTLVYNPGAAFSFLADQGGWQKYFFLVLAVAVSAYLVRAILRDEFAALGKIGAAMIIGGASGNVIDRLIHGHVVDFLLFYWQNWFYPAFNIADSFICVGAVLAVLDNIVHRKDSKKT
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISAA_STAES
Sequence: MKKTVIASTLAVSLGIAGYGLSGHEAHASETTNVDKAHLVDLAQHNPEELNAKPVQAGAYDIHFVDNGYQYNFTSNGSEWSWSYAVAGSDADYTESSSNQEVSANTQSSNTNVQAVSAPTSSESRSYSTSTTSYSAPSHNYSSHSSSVRLSNGNTAGSVGSYAAAQMAARTGVSASTWEHIIARESNGQLHARNASGAAGLFQTMPGWGSTGSVNDQINAAYKAYKAQGLSAWGM
What is the function of this protein?
Is able to cleave peptidoglycan.
What are the official names of this protein?
Probable transglycosylase IsaA, Immunodominant staphylococcal antigen A.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. IsaA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_STAA1
Sequence: MLRIAIAKGRLMDSLINYLDVIEYTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPETTNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2513_MOUSE
Sequence: MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVKQIFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNAKTGKVSAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTRSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGNRKDVEVTKEEFALAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGMLPFNLAEAQRQQKASGDAARPFLLQLAESAYRFGLGSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYNGVTDCFRKILREEGPKALWKGVAARVFRSSPQFGVTLLTYELLQRWFYVDFGGVKPVGSEPVPKSRITLPAPNPDHVGGYKLAVATFAGIENKFGLYLPLFKPSASTSKVTAGDS
What is the function of this protein?
Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (By similarity).  Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton.  Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (By similarity).
What are the official names of this protein?
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial, Citrin, Solute carrier family 25 member 13.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PUR5_VIBC1
Sequence: MSGNNSSLSYKDAGVDIDAGNALVDRIKGAVKRTRRPEVMGGIGGFGALCELPTKYKQPVLVSGTDGVGTKLRLALDMNKHDTIGVDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAADVVSGIADGCVQAGCALIGGETAEMPGMYEGEDYDVAGFCVGVVEKEDVIDGTKVAAGDALIAVGSSGPHSNGYSLIRKILEVSGADKNEELAGRTIGEHLLEPTKIYIKSALKMIEKHDIHAISHITGGGFWENIPRVLLEGTKAVIDGNSWEWPIIFKWLQEKGNVETHEMYRTFNCGVGLVVALPKDQADAAVALLKEEGENAWVIGEIAQAEANEEQVEIQ
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSB_ECOBW
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OPSD_GLOME
Sequence: MNGTEGLNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSVLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYIPLNLAVANLFMVFGGFTTTLYTSLHAYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWVMAMACAAPPLVGWSRYIPEGMQCSCGIDYYTSRQEVNNESFVIYMFVVHFTIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWVPYASVAFYIFTHQGSDFGPIFMTIPSFFAKSSSIYNPVIYIMMNKQLRNCMLTTLCCGRNPLGDDEASTTASKTETSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Required for photoreceptor cell viability after birth (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: Y163_BARBK
Sequence: MAGHSQFKNIMHRKGRQDAVRSKVFSKLAREITVAAKQGSPDPAMNPRLRLAVQNAKSQSMPKDNIERAIKKASGGDVENYDEVRYEGYGPGGVAIIVEALTDNRNRTASNVRAAFTKAGGALGETGSVGFMFNRIGEIIYKPEAGTAESVMEAAIEAGAEDVQSEETGHHITCAFEDIGEVSKMLEATLGEAESIKTIWKPTTLAPVDEEKAMSILRLISTLEEDDDVQNVYANFDVSDEVLAALSA
What are the official names of this protein?
Probable transcriptional regulatory protein BARBAKC583_0163.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPC_YARLI
Sequence: MISAIRPAVRSSVRVAPMANTAFRAYSTQDGLKERFAELIPENVEKIKKLRKEKGNTVIGEVILDQAYGGMRGIKGLVWEGSVLDPEEGIRFRGLTIPDLQKQLPHAPGGKEPLPEGLFWLLLTGEIPTDAQVKGLSADWASRAEIPKHVEELIDRCPPTLHPMAQLGIAVNALESESQFTKAYEKGVNKKEYWQYTYEDSMNLIAKLPVIASRIYRNLFKDGKIVGSIDNSLDYSANFASLLGFGDNKEFIELLRLYLTIHADHEGGNVSAHTTKLVGSALSSPFLSLSAGLNGLAGPLHGRANQEVLEWILEMKSKIGSDVTKEDIEKYLWDTLKAGRVVPGYGHAVLRKTDPRYTAQREFALEHMPDYDLFHLVSTIYEVAPKVLTEHGKTKNPWPNVDSHSGVLLQYYGLTEQSYYTVLFGVSRAIGVLPQLIMDRAYGAPIERPKSFSTEKYAELVGLKL
What is the function of this protein?
Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate.  Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism.  Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.
What are the official names of this protein?
2-methylcitrate synthase, mitochondrial, Methylcitrate synthase, (2S,3S)-2-methylcitrate synthase, Citrate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NIFW_POLNA
Sequence: MENFLQQLKTLSSAEDFMQYFGVPFDQKVMNISRLHILKRFFQYLRQETPLAQTDELQMFTAYRALLTKAYGDFVTSTPAQEKVFKVFQDTDGKQHVTLDSLRASMPQRAAAA
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: HIS6_LEIXX
Sequence: MGVAVRVIPCLDVAAGRVVKGVNFQNLRDQGDPVEFARRYAEQGADELTFLDVTATVDDRSTTYDVVRATAGQVFIPLTVGGGVRSTEDVARLLGSGADKVGVNSAAIARPGLVAEIADRFGAQVLVLSLDVKRSASTDSGFAVTTHGGRTETGLDALEWAARAIELGAGELLVNSIDADGTKEGFDLELIREMRALSAVPVIASGGAGKTADFAPALRAGADAVLAASVFHSGELTIGDVKTALAAAGMEVRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAS1_THISK
Sequence: MMHLLRRGAFAILLIVLLPSAALADLRLASWNIQHLGWNVGKDYPAVARIAAQFDFLAIQEVMNAEGIYRLRDTLEDATGAEWSVLYSDALGRNTYREKYAFLWREAAVEYVGGALTYIDEADRFAREPFSAVFRSRGTDQHFLAATVHITYGDRVADRVEEIEALRRYWDWLADVMPEYAGERILFGDFNLPPHHDGWASMRAVAEPLVTEGATTLSTHDRRYANLYDNLWVPKDHTLPLGDAGILPFPVVLSEVTGVYWDHEKARDRVSDHAPVYVLFEGNTLHDAVVAEIADQEAGCIDLNRASVSELTALPHIGEARAEAIKDGRPWNAVRDLKEIRGIGAGRLEEIKARGEACIEP
What is the function of this protein?
DNA nuclease able to digest short and long DNA substrate.  Is resistant to ionic strength and thus active at high salt concentration.
What are the official names of this protein?
Deoxyribonuclease, DNase.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRBE1_SINFN
Sequence: MVALKRFRATGPSFADLVPYAGLVDNGVLLLKDGSLMAGWYFAGPDSDSATDFERNELSRQINAILSRLGTGWMIQVEAARIPTYDYPSEDRCHFPDAVTRAIDAERRAHFARERGHFESKHALILTYRPSEAKKTAAQQIHLLGRGEP
What are the official names of this protein?
Probable conjugal transfer protein TrbE part 1.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
Protein: SND1_YEAST
Sequence: MDTVGTDAAAASINERRFAQSTSPKVSVKSQDSLFLITYSNMQQTVVQASLADRYPSLKKLNILLYIDIPTIDYYNDEMTHNKLSRLNKRFKLHRLRNSIAQSFSNTSTAEDNDKFWEELKSLISSRSTPENKFDLNVLVSSSGSLRYVETIRFLVEKLFNSFKDLYVQKKLNLCFQINVSPTSLKWFSTFLNAELLNLKIINWQNIGSFTKTIQNSKSLPFKEYYTKLNEKFTGSNQSNGSMQDQTVLDSIVIVTNSTGVKALLTLLSDHPLTSLISQESIKALHEYSDAVNEDKGDDQSNTSLKRNSSSLLNFQNSVLTSNKDKSVRIRSLSINRKSNRAHMFKTNESITTIPSTSINNLIGQESNLRKQPSGTALHLQSHLHPHSRSQSYSSSNMSRSPSPFPYGKTPSNDELVYDELNNQINEVQDRAKNEEIVLYNNNNYDDYTKERGEQEQDRTSYADEYGFNYDDEEGGNEDNYDDDEDDDDDDDDDDESDDEGLSFYAPSILSRSGSSTDVLSSGIDSMAKNSKETRGRFRSLSLMDPALQKPFNQKFPNSQQPDSAGASSPKRSTSSNHFTNVYVHDGDFDGTDTINNKKNLSSATLIKRKSLMNRNLAPSISNGLIPPEFISRISTPSTSASSSNSSLNDMSTVSNAFSKLLNDTSKKQKFLNSPIPQHTQQASPLLMRNNSNSNLLFEKNLINKSFEELRRQPSVNLFSTLMNGNMEKNGLALNFKSRTPTDALMANSIKNSNNSSHRLLNLEEEDQIMSGSLPKEREDDNDSTNSTIVPNHPDNDNYNDNDNDNNTGINSNNFNLNLYDDNDSAGFTDVTTEGVKYSNSNSTVTKPVYKKAVTLDLYGEDDMDNMGGWVLGGNAR
What is the function of this protein?
Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum.  SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs.
What are the official names of this protein?
SRP-independent targeting protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_NOVAD
Sequence: MTHQVHIIGGGMAGTEAAWQLARRGIRVRLSEMRGGGDTTPAHNGDGLAELVCSNSFRSDDDEKNAVGLLHYEMRQCDSLLMAAAAKARVPAGSALAVDRDVFSAEVEAALRAQPTLEIVRERVDVLPSDGLTIVATGPLTAPSLANSIGSATGADSLAFFDAIAPIVYRDSIDMGVAWMASRWDKGAEASLAMGGDGRDYINCPMTRDQYLAFREELLAGEKTEFKEWEANTPYFDGCMPIEVMAARGEETLRFGPMKPVGLDNPHWATAEHPNGRWPYAVVQLRQDNKLGTLWNMVGFQTKLKHAEQVRVFRTIPGLENAEFARLGGLHRNTFLNSPTLLDRQLRLKSAPNVRFAGQITGCEGYVESGSVGMLAGLMVAAQIAGLDWSPPPRTTALGALLAHITGDAEAESFQPMNVNFGLFSPVDASVKKKVRKEAYTARAKADLSDWIATLA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_SHISS
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_SALSV
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPLADHLLEPTRIYVKSVLELIENVDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQWPAIFTWLQTAGNVSRHEMYRTFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFE_ALISL
Sequence: MATHKELIKNGLWDNNPALVQLLGLCPLLAVSATVTNALGLGIATTLVLIGSNLIVSLVRQWIPQEVRIPVFVMIIASLVTCVQLLMNAYAYGLYLSLGIFIPLIVTNCIIIGRAEAFASKNDPLPAALDGLWMGLGMTSVLVLLGAIREILGNGTLFDGADLLLGDWATTLRIELFHVDSHFLLAMLPPGAFLGVGFLIAIKNIIDKKLADRQPKQEKTEIERARVS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3SOBB_DENAN
Sequence: MICYSHKTPQPSATIGCEEKTCYKKSVRKL
What is the function of this protein?
Blocks voltage-gated potassium channels (Kv).  This is the slowly inactivating phase of potassium efflux which is blocked by this toxin.
What are the official names of this protein?
Dendrotoxin B, DTX-B.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XI sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TLL2_MOUSE
Sequence: MPLATTLGTLVLLLLLPLPRGAEVTGDHSNVALDYGALEGEEGTEQQLHYHDPCKAAVFWGDIALDEDDLKLFHIDKAEDWTKPSIDKPGHDTGGLEETSARWPNDTASNASIQAPRKDGKDATTFLPNPGTSNTTAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEESFIVFSYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIILNFTSMDLFKSRLCWYDYVEIRDGYWRKAPLLGRFCGDKIPESLVSSDSRLWVEFRSSSSSLGKGFFAVYEAMCGGDITKDAGQIQSPNYPDDYRPSKECVWRITVPDGFHVGLTFQSFEIERHDSCAYDYLEIRDGPTEDSTLIGHFCGYEKPEAVKSSANRLWVKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEQRCVNTLGSYTCACDPGYELAADKKTCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPVQYRISLQFEAFELEGNDVCKYDFVEVRSGLSPDAKLHGKFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQQECVNTFGSYLCRCRNGYRLHENGHDCKEAGCAYKISSAEGTLMSPNWPDKYPSRKECTWNISSTAGHRVKITFSEFEIEQHQECAYDHLELYDGTDSLAPILGRFCGSKKPDPVVATGSSLFLRFYSDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSQARCDWVIVAEDGYGVELIFRTFEVEEEADCGYDFMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFHTDDTINKKGFHARYTSTKFQDALHMRK
What is the function of this protein?
Protease which specifically processes pro-lysyl oxidase.  Required for the embryonic development.  Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
What are the official names of this protein?
Tolloid-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: YIEE_ECOL6
Sequence: MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRGLLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLDMELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLNDDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWKSLPDIHSRANNPTSRMMRFAQLSTVKAFSPN
What are the official names of this protein?
Uncharacterized protein YieE.
Protein: Y2273_MYCTU
Sequence: MNRHSTAASDRGLQAERTTLAWTRTAFALLVNGVLLTLKDTQGADGPAGLIPAGLAGAAASCCYVIALQRQRALSHRPLPARITPRGQVHILATAVLVLMVVTAFAQLL
What are the official names of this protein?
Uncharacterized protein Rv2273.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGA_SALDC
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAF5_HUMAN
Sequence: MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDLTDLEDL
What is the function of this protein?
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.  Mediates activation of NF-kappa-B and probably JNK.  Seems to be involved in apoptosis.  Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
What are the official names of this protein?
TNF receptor-associated factor 5, RING finger protein 84.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
Protein: XYLA_SALNS
Sequence: MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHDVDVSPEGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELDKRVAKRYAGWNGELGQQILKGQLSLGELAQYAEQHNLAPVHQSGHQELLENLVNRYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INS2_BATSP
Sequence: MAPPQHLCGSHLVDALYLVCGDRGFFYNSGIVEQCCHRPCDKFDLQSYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin 2.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERCC3_DICDI
Sequence: MSSGDSNLKRRRGGNTGQSSKSYNTWTDYEEDLEESGEFNQSIKKTTNTSSATLTSSEEKGSLLDYSKRCILKQDNKSRPIWVCPDGHIFLETFSAIYKQASDFLVAIAEPVCRPQNIHEYQLTPYSLYAAVSVGLETNDIITVLGRLSKLALPKEVEQFVRQCTQSYGKVKLVLQKNKYFVESAYPEVLEFLLKDSSIATARIKPTLEESVVDPKTGFIINKEVVTGAQISGGLQANQSLDPVLKNDALSNLLEEEEEDTVNNSDQHFHSFEIDPQQVEEVKKRCIQLDYPVLEEYDFRNDTVNPNLNIDLKPTTMIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKSLSGITAACTVKKSILVLCTSAVSVEQWKYQFKLWSNIEERQISKFTSDNKEKISNVAGVTITTYTMVAFGGRRSAESLKIMNEITNREWGLVLLDEVHVVPAAMFRKVLTVTKAHCKLGLTATLLREDEKIQDLNFLIGPKLYEANWLDLQKAGFLANVSCSEVWCPMTAEFYKEYLINDSQGKKKLLYTMNPNKFRACEYLIRFHEQRGDKIIVFSDNVYALQKYAKGLGRYFIYGPTSGHERMSILSKFQHDPTVRTIFISKVGDTSIDIPEATVIIQVSSHYGSRRQEAQRLGRILRPKPKSDGLYNAFFYSLVSKDTQEMYYSTKRQQFLIDQGYSFKVISELPGIDQEVNLKYSSKQDQLDLLAQVLGEGEDSGKNEILEEDFDDITRGAKKSKSSAPTVSRTTGGSTRALSGGNDMNYMEYQAPAIYKSIPTQHALFKQRAKNKQ
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB/repB, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB/repB is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, DNA excision repair cross-complementing protein-3 homolog, DNA repair helicase repB, DNA repair protein B.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATA_CAMJD
Sequence: MGGWSSPSHWLIILLIVVLLFGAKKIPELAKGLGKGIKTFKDEMNNDDEVAKNTQKIEENKNTTNNTNADASIDETKKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.