PharMolix/UniProtQA huggingface dataset:
Protein: MLO10_ARATH
Sequence: MATRCFWCWTTLLFCSQLLTGFARASSAGGAKEKGLSQTPTWAVALVCTFFILVSVLLEKALHRVATWLWEKHKNSLLEALEKIKAELMILGFISLLLTFGEQYILKICIPEKAAASMLPCPAPSTHDQDKTHRRRLAAATTSSRCDEGHEPLIPATGLHQLHILLFFMAAFHILYSFITMMLGRLKIRGWKKWEQETCSHDYEFSIDPSRFRLTHETSFVRQHSSFWTKIPFFFYAGCFLQQFFRSVGRTDYLTLRHGFIAAHLAPGRKFDFQKYIKRSLEDDFKVVVGISPLLWASFVIFLLLNVNGWEALFWASILPVLIILAVSTKLQAILTRMALGITERHAVVQGIPLVHGSDKYFWFNRPQLLLHLLHFALFQNAFQLTYFFWVWYSFGLKSCFHTDFKLVIVKLSLGVGALILCSYITLPLYALVTQMGSNMKKAVFDEQMAKALKKWHMTVKKKKGKARKPPTETLGVSDTVSTSTSSFHASGATLLRSKTTGHSTASYMSNFEDQSMSDLEAEPLSPEPIEGHTLVRVGDQNTEIEYTGDISPGNQFSFVKNVPANDID
What is the function of this protein?
May be involved in modulation of pathogen defense and leaf cell death.  Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).
What are the official names of this protein?
MLO-like protein 10, AtMlo10.
What is the protein family that this protein belongs to?
Belongs to the MLO family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SSRP_STRPD
Sequence: MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSGMTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ERF69_ARATH
Sequence: MKRIVRISFTDMEATDSSSSEDESPPSSRRRGKKLVKEIVIDHSDPPEVGKTRFKIRIPASLLAARNTTANKKKFRGVRQRPWGKWAAEIRCGRVKGRPERIWLGTFETAEEAALAYDNAAIQLIGPDAPTNFGRPDVDSAVVKKQDSDASGGASEEVV
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF069.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELA_ECOLU
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDIPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATVRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS4_HUMAN
Sequence: MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDEWVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLVSNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
What are the official names of this protein?
Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7.
Protein: AMPP2_TALSN
Sequence: MSPSPALHAAAFQGIGAPDIQRFHINLSVGSNVNRYPAKQHARKVASKLGISRGLIYLVGKPTVFLDDSDQTIPFRQRRYFYYLSGANEPDCHLTYDIAKDHLTLYVPDFDLRQTVWMGPTISIGEALDRYDIDNARYAGSLQTDISGWLRLRGDDSQIILLHPDHRPPIEYEQDLFETKNLVPAMNAARGVKDSYEIEMIRKANIVSGLAHTAVLEKIGQMTNESDIAGLFLETCMTHGAPDQAYGIIAASGENGATLHYMKNNEDFGNRLSVCLDAGAEYECYASDVTRTFPISRTGEWPTPEVRDIYLAVERMQEECIRLIKPGVRFRDVHLHASRVAVEELLKLGVFQKDNSVDAIMASGAVSVFFPHGLGHHVGLEVHDVAEQSVMAATDDSSPRTRVRGFLMQPASAMSAALLEESMIVTVEPGIYFNRLALKNARTLPIARFIDFDVVERYYPIGGVRIEDDILVTATGYENLTTAPKGEEALDIIRRSSVKSSRA
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase TSTA_094700, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: HIS7_ERYLH
Sequence: MRTGRIERNTAETRILIEVNLDGRGNYDVSTGIGFLDHMVEQFSKHSLIDVTMKVDGDLHVDQHHTTEDSAIALGQALGEALGDKAGIGRYGQAYSPMDETLSRVALDISGRPYTVFRAGFSQEKLGEWDTELIEHWFQSVAQAAGITLHIELLYGTNNHHICESIYKGFARAMRQAVELDGRKGGAIPSTKGQLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB7_HUMAN
Sequence: MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Within the 20S core complex, PSMB7 displays a trypsin-like activity.
What are the official names of this protein?
Proteasome subunit beta type-7, Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome subunit Z.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: MUTS_CLOB1
Sequence: MGLTPMMRQYLEVKESCKDCILFFRLGDFYEMFFEDAKVASKELELVLTGRDCGLEERAPMCGIPYHAANTYIGRLVSAGYKIAICEQLEDPSASKGIVKRGIIKIITPGTYTDSSFLEENKNNYIMSFYLDDNMCAMSFADISTGEFNSTHSNFKEAVVLDEISKFAPREIVLEENIKESFIHTIKERFPNISISKIKQENFDYNIDNNLKEQFNNFNENEYETIVKKSANGLLYYIFHTQKNILSNINKIDYYSIVDYLTIDVNSRRNLEITENLREKTKKGSLLWALDKTNTAMGGRQLRRWIEQPLINKNPIENRLNAVEELLNNISLQEDLKEDLKSIYDIERIVGKVASKSVNAKELISLKCSIGKVPYIKEYLSNFKSDLFLNMEQCIDTLEDIHKLLDKALLDNPSLSVKEGNIIKEGFNEEVDSLREAKSNGKKWIASLEQKEKEETGIKSLKVSYNKVFGYFIEITKANLNLVPEGRYIRKQTLSNAERYITPELKEMEEKILGAEEKLIDIEYKLFTEIRDFIEENIDRMQKTARIISDIDCLCSLATVALENNYIKPNINAKDEILIEEGRHPVVEKVIPKGEFISNDSLIDTKENQLILITGPNMAGKSTYMRQVALITIMAQIGSFVPAKKANISICDKIFTRIGASDDLAAGKSTFMVEMWEVSNILKNATSKSLVLLDEVGRGTSTYDGLSIAWSVIEYICNNKNLRCKTLFATHYHELTKLEDNIEGVKNYSVSVSELENEIVFLRKIIKGGADQSYGIEVAKLAGLPSPVINRAKEILQHIEGDKEENSLNIAPSKEYKSKDYIEVSKDTSNTKNNLGSEIKHDTLSETNTDTIIEDESTKEHLSSNKKQINCRINDEKSIKKEVAVDSFQINFEYIKRDKIIEEIKNIDILNMTPMEGFNKLYDIINKTKDID
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y2042_RICFE
Sequence: MHHLIDQLKSKNNIFYIRALVPMIVLCVLLISKTVYGYDTKLEHLCKAISNNNIDLVKQAQQKSQYNQRCIQERETPLILAISNNNIKVVQMLLDFGVDIEQEGRYGGAALYNAICHDTNIVKLLIKHGANINKRLSEGSRETPLIKATKCFENGSIANTEHIKILLKYGADINAKDVNGITALKMAEMQNDQSAINLLRSSGKK
What are the official names of this protein?
Putative ankyrin repeat protein RF_p42/RF_pd42.
Protein: RBFA_LACAC
Sequence: MKHRVGRVEGEILRELTKILRKDIRDPRLSEVTITAVECTNDLSYATIYYSLLTEDAEKEKEVQEGLDKAKGMMRHLLGQTLTVYKVPELIFKRDNSVKYGSKIDRLIAEVKKQDAERASK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_ECOLU
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMALLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIRDGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL252_SYMTH
Sequence: MQLEATPRGTGSRASRRLRQAGFVPGIIYGPGVEPLAVSVRSTQLERLVERQGRGHLIHVQVEGEANPRQVVIKQLQRDILTQQVTHVDFLQVDMNRTITLTVPIVVVGEEQARRRGLLITHELDEVEVECRPTEIPEAVTLDVSGLTEPGPVTAASLSAPPGVRVLEDPDTVVVSCTVIGGGEEEEASTGPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25 2, General stress protein CTC 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: MIAB_COXB2
Sequence: MKKLYLKTHGCQMNEYDSAKMADVLKFSHGLELTEDPAVADVFLLNTCSVREKAQTKVFSELGRWRPFKEKRPHVVIGVGGCVASQEGETILKQAPFVDIVFGPQTLHRLPDLLDSVIQKRKSVVDITFPEIEKFDRLPQPRAEGPSAFVSIMEGCSKYCTFCVVPYTRGEEISRPFDDVIAEVASLCEQGVREITLLGQNVNDYRGLMHDGQVADLALLIHYLAAMDNIERIRFTTSHPSAFSENLIDAYAEEPKLANHLHLPVQSGSDRILAAMKRNYTVLEYKSKIRKLRAVRPDISLSSDFIIGFPGETDADFEATMNLIHDMGFDHSFSFIYSPRPGTPAAQLPDDVPMAVKKERLAILQNRINAKAAEISQSMVGTQQRILVTGPSKKYPDQLSGRTENNRVVNFNGDTPLIGQMVTIKIKEARPYSLWGEIC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFCA_ECOLI
Sequence: MKHKLSAILMAFMLTTPAAFAAPEATNGTEATTGTTGTTTTTTGATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR
What are the official names of this protein?
Threonine-rich inner membrane protein GfcA, Group 4 capsule protein A homolog.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=When the protein is overexpressed.
Protein: SECA_FRAT1
Sequence: MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMRTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDRSEMYNLFNRLVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNAKQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQRMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVPAGSMHELWDLEGLEKALKSDFMIELDLQKLYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVKQVRREGPKVKRNDPCPCGSGKKYKQCHSKVE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ISCS1_BACSU
Sequence: MERIYLDHAATSPMDERVLEQMIPHFSGSFGNPSSIHSFGRESRKWVDEARAQIAAEIGAAEQEIIFTSGGTEADNLAIMGTALARKDLGRHIITTKIEHHAVLHTCEKLEGDGFDITYLDVDQNGRVSAKQVKEALRDDTILVTVMYGNNEVGTVQPIEEIGELLKEHKAYFHTDAVQAFGLLPIDVKNSHIDLLSVSGHKLNGPKGTGFLYASKDVKLSPLLFGGEQERKRRAGTENVPGIVGLKEAIKLSSEERDEKNEKYQSFKAIFADTLRDAGVAFEVNGDKEHSLPHVLNLYFPGVSVEALLVNLDMAGVAVSSGSACTAGSVLPSHVLTAMFGEESDRLTSSIRISFGLGNTAEQVKTAAKHVADVVKRLT
What is the function of this protein?
Catalyzes the removal of elemental sulfur from cysteine to produce alanine.
What are the official names of this protein?
Putative cysteine desulfurase IscS 1.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
Protein: TPIS_THET8
Sequence: MRRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQSEAAVLPAFPILPVAKEVLAETQVGYGAQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEGITPILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATPEDAEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLELESFLALLRIAG
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_HCMVM
Sequence: MRPGLPSYLIILAVCLFSHLLSSRYGAEAVSEPLDKAFHLLLNTYGRPIRFLRENTTQCTYNSSLRNSTVVRENAISFNFFQSYNQYYVFHMPRCLFAGPLAEQFLNQVDLTETLERYQQRLNTYALVSKDLASYRSFSQQLKAQDSLGEQPTTVPPPIDLSIPHVWMPPQTTPHGWTESHTTSGLHRPHFNQTCILFDGHDLLFSTVTPCLHQGFYLIDELRYVKITLTEDFFVVTVSIDDDTPMLLIFGHLPRVLFKAPYQRDNFILRQTEKHELLVLVKKDQLNRHSYLKDPDFLDAALDFNYLDLSALLRNSFHRYAVDVLKSGRCQMLDRRTVEMAFAYALALFAAARQEEAGAQVSVPRALDRQAALLQIQEFMITCLSQTPPRTTLLLYPTAVDLAKRALWTPNQITDITSLVRLVYILSKQNQQHLIPQWALRQIADFALKLHKTHLASFLSAFARQELYLMGSLVHSMLVHTTERREIFIVETGLCSLAELSHFTQLLAHPHHEYLSDLYTPCSSSGRRDHSLERLTRLFPDATVPATVPAALSILSTMQPSTLETFPDLFCLPLGESFSALTVSEHVSYIVTNQYLIKGISYPVSTTVVGQSLIITQTDSQTKCELTRNMHTTHSITVALNISLENCAFCQSALLEYDDTQGVINIMYMHDSDDVLFALDPYNEVVVSSPRTHYLMLLKNGTVLEVTDVVVDATDSRLLMMSVYALSAIIGIYLLYRMLKTC
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA (PubMed:28403202).  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (PubMed:17942555, PubMed:23853586, PubMed:30057110, PubMed:28783665).
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans- Golgi network (TGN).
Protein: CYB6_TRIEI
Sequence: MFSKQVTDSPAYKWFDERLEVQALADDISSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVTEALASVQYIMTEVNFGWLIRSIHRWSASMMVLMMILHTFRVYLTGGFKKPRELTWVTGVVMAVITVSFGVTGYSLPWDQIGYWAVKIVSGVPDAIPFVGPFIVELMRGSTSVGQATLTRFYSLHTFVLPWFIAVFMLLHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ATPD_TRICV
Sequence: MSINPLASKIAAPYARALFDFSVDQNLMHQITADFQNLEVFLNKTPDLTEYLSNPLISAKSKEEVLNKTLKSQINKETFKFLIVLVNRSRINLLEPIIASYLNLVYNAASVKMIEVSTAYAFTNLQKNTLIKKLKELTNAREIRLVITVDSSLIGGFLIKTNSKVLDFTIKNQLQKLAKHLDSVLEI
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, chloroplastic, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RNH_GEOMG
Sequence: MSTRVELFCDGACSGNPGVGGWGGILRCGATEKELSGAEWETTNNRMEMTAAIRGLEALTRPCEVVVTTDSQYLVKGMTEWLSGWIRRGWVNSKKEPVLNRDLWERLLELSKTHRIQWTWIRGHNGHAENERCDALARGAIDELRKKGQGRR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_LEPBL
Sequence: MNENTFEKTKIKICGIRDLEIAKICREEGADYIGLNFVPSSPRKISLKDAQKIVEFYRDTKNSPEIVLLFYQNSPEEIRTVTSSLYHDLIQWVWDDPKLTFVDRKNFLGKRQICSYRVNSPIYNEDLKNIPSELLILDSYSKDAGGGTGETFNWNFISRIERKFLLAGGLNSSNVSNAIRTVKPYGVDVASGVESSPGIKDSQKVIQFIRNVRLGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: DEF1_HORVU
Sequence: RICRRRSAGFKGPCVSNKNCAQVCMQEGWGGGNCDGPLRRCKCMRRC
What is the function of this protein?
Inhibits protein translation in cell-free systems.
What are the official names of this protein?
Defensin-like protein 1, Gamma-hordothionin.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: RL5_MESFL
Sequence: MKSRLETRYTEQIAPELFKELGYKSVMQVPKLTKIVINMGVGEATTDPKKLDAAVVELEQLTGQKPLVTKAKKSLAVFKLREGMPIGTKVTLRGKKMYDFLDRLTNVALPRVRDFRGVPKTSFDGFGNYTMGIKEQIIFPEIDYDKVQKLRGMDITIVTTAKTNEEAYKLLEKFGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.