PharMolix/UniProtQA huggingface dataset:
Protein: LON_XANOR
Sequence: MQHLADGPITGPSAFLFPQIPIPAERPMAQSQPEVLDLPVLPLRDVVVFPHMVIPLFVGRDKSMRALEKAMEADKRILLVAQKSAETDDPAAVDLHTVGTLAQVLQLLKLPDGTIKVLVEGLSRVTVDKVVEQDGALQGQGTEVEASDAREPREVEAIARSLMSLFEQYVKTNRKLPPELLQTLAGIDEPGRLADTIAPHIGVRLADKQRLLEITDIGERLELLVGLVDGEIDVQQLEKRIRGRVKSQMEKSQREYYLNEQMKAIQKELGDLDDVPGELEELARKIAEAGMPKPVETKAKAELNKLKQMSPMSAEAAVVRNYLDWLLGVPWKKRTKVRKDLKVAEDTLDADHYGLDKVKERILEYLAVQSRVKQMKGPILCLVGPPGVGKTSLGQSIAKATNRKFVRMSLGGIRDEAEIRGHRRTYVGSMPGRLVQNLNKVGSKNPLFLLDEIDKMSMDFRGDPSSALLEVLDPEQNNSFNDHYLEVDLDLSEVMFVATSNSLNIPGPLLDRMEVIRIPGYTEDEKLNIAMRYLVPKQIKANGLKPEEIEIGGDAIQDIVRYYTRESGVRNLEREVAKICRKVVKEIALAGPQPAAKKAVAKKGKPKALVTVNAKNLDKYLGVRRFDFGRAEEENEIGLVTGLAWTEVGGELLQVESTLVPGKGNLILTGQLGNVMKESASAALSVVRSRAERLGIDVDFLQKQDVHVHVPDGATPKDGPSAGIAMVTSLVSVLTKVPIRADVAMTGEITLRGRVSAIGGLKEKLLAALRGGIRTVLIPGENRKDLADIPANVTRDLKIVPVKWIDEVLDLALERPLTPKKAGKEKARKTAPRVAVRGKSRSTPGTRVKH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_XYLFT
Sequence: MKVLSSLKSAKTRHRDCKVILRRGKIFVICKSNPRFKARQR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RS6_SHEB8
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGVITEANGTIHRLEDWGRRQLAYPILDLHKAHYVLMNVEAKAETIEELETAFRFNDAVLRNMVMRTKVAVTEASPMAKARDERDSRRGPAGERSYDEAHAEEIAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MOT11_MOUSE
Sequence: MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAGGTGSIRDTTC
What is the function of this protein?
Proton-linked monocarboxylate transporter.  It catalyzes the transport of pyruvate across the plasma membrane.  Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids.
What are the official names of this protein?
Monocarboxylate transporter 11, MCT 11, Solute carrier family 16 member 11.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RIBB_VIBVU
Sequence: MNQSSLLAEFGDPITRVENALLALKEGRGVLLLDDEDRENEGDIIYSVEHLTNAQMALMIRECSGIVCLCLTDEHANKLELPPMVVNNNSANQTAFTVSIEAKQGVTTGVSAQDRVTTIKTAANPSAKADDLARPGHVFPLRARPGGVLARRGHTEGTVDLMQMAGLQPAGVLCELTNPDGTMAKTPEIIAFGKQHNMPVLTIEDMVMYRNQYDLKLA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: COA3_KLULA
Sequence: MLEPSPYQDHKTWKMTPAMIRARQPFFKKNLMGLVILLGVTGTIYTYTYKMLNKDSDFADVPIPPIDEKELEQLKKEYELEKIRRAQK
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PSBY_TRICV
Sequence: MDSRLLVIAAPLLVAASWALFNIGRLAIQQIQRLSA
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CYB_VAMCA
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLVMLTALSALVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILAIIPILHTSKQRSMMFRPLSQYLFWLLVATLFTLTWIGGQPVEHPYIIIGQTASILYFLIILVFMPTISIMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CH60_LISMF
Sequence: MAKDIKFSEDARRAMLRGVDQLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDPFENMGAKLVSEVASKTNDVAGDGTTTATVLAQAMIQEGLKNVTAGANPVGVRRGIEKAVATAIEELKAISKPIESKESIAQVAAISSGDEEVGKLIAEAMERVGNDGVITIEESKGFATELDVVEGMQFDRGYTSPYMVTDSDKMEAVLEKPYILITDKKINNIQEILPVLEQVVQQGRPMLIIAEDVEGEAQATLVLNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGQVITEDLGLELKTATVDQLGTANKVVVTKDDTTIVEGAGDSTQISARVNQIRAQMEETTSEFDREKLQERLAKLAGGVAVVKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVSIYNKVAALEAEGDVETGINIVLRSLEEPVRQIAHNAGLEGSVIVERLKHEAVGVGFNAANGEWVNMIDAGIVDPTKVTRSALQNASSVAALLLTTEAVVADKPDENGPAAVPDMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCE1D_HUMAN
Sequence: MSCQQSQQQCQPPPKCTPKCTPKCPAPKCPPKCPPVSSCCSVSSGGCCGSSSGGGCGSNSGGCCSSGGGGCCLSHHRRHRSHRRRPQSSDCCSQPSGGSSCCGGGSSQHSGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 1D, Late envelope protein 4.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: HIP26_ARATH
Sequence: MGVLDHVSEMFDCSHGHKIKKRKQLQTVEIKVKMDCEGCERKVRRSVEGMKGVSSVTLEPKAHKVTVVGYVDPNKVVARMSHRTGKKVELWPYVPYDVVAHPYAAGVYDKKAPSGYVRRVDDPGVSQLARASSTEVRYTTAFSDENPAACVVM
What is the function of this protein?
Heavy-metal-binding protein.  Binds lead, cadmium and copper.  May be involved in heavy-metal transport (PubMed:18823312).  May be involved in cadmium transport and play a role in cadmium detoxification (PubMed:21072340).
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 26, AtHIP26, AtHIPP26, Farnesylated protein 6, AtFP6.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
What are the subcellular locations of this protein?
Nucleus membrane. Cell membrane. Note=PubMed:18974936 shows that isopernylation may be important for a speckle-like nuclear localization in a heterologous system, while PubMed:18823312 shows a plasma membrane localization.
Protein: HAT1_ORYSJ
Sequence: MALKQKGTDAAADPKKRRRVGFSGIDAGVEANECMKVFIARNPDEAGSANSTSLQPFDLNHFFGEDGKIYGYKNLKINVWISAISFHAYADISFEETSDGGKGITDLKPVLQNIFGENLVEKDEFLKTFSKECEYLSNVVTDGNVIKHDASIDEDSAVEIVRVELQGAAAFLYCRLVPLILLLVEGSTPIDITEHGWEMLLVVKKSAQASSSSNFLVLGFAAVHHFYHYPESTRLRISQILVLPPYQGEGHGLRLLETINSISESENIYDVTIEDPSDYLQYIRSSIDCLRLLTFDPIKPALCSMVSSLKDTNLSKRTSSLKMVPPSDLAETVRQKLKINKKQFLRCWEILIYLNLDAEDRKSMDNFRACIYDRIKGEILGTSTGPNGKRLVQMPSNFDEETCFAVYWTQDGGDADDQTVEQQPEDLKTQEQQLNEVVDSQMEEIVEIAKNVTSRGKDKLSVSCSV
What is the function of this protein?
Acetylates soluble but not nucleosomal H4.
What are the official names of this protein?
Probable histone acetyltransferase type B catalytic subunit, HAT B.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PQQB_RHIME
Sequence: MNKTSDLRIIVLGAAAGGGLPQWNCGCRNCAMARDPASGLRPQTQSSLAVSLDGESWTVFNASPDIRQQVQDNCPLQPRRLRHSPIESVVLTNGDIDHLAGLLVLREKQAFTLFSTGAVGRIVSDNPVFQVLDPELVSRKTIEIDEAFSPLSGLDARLFAVPGKVPLFLEDGEPDLGIEGEHTVGLELEATGRRVYYVPGCAMMTDSLAARLRDADAVFFDGTLFSDDEMILTGTGRKTGRRMGHMPIDGEGGSLDALDLLNIRRKIYVHINNTNPIWRAGSERERVEARGFEIGYDGMEVRL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: HS905_ARATH
Sequence: MAPALSRSLYTSPLTSVPITPVSSRLSHLRSSFLPHGGALRTGVSCSWNLEKRCNRFAVKCDAAVAEKETTEEGSGEKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIGMTKEELIDCLGTIAQSGTSKFLKALKENKDLGADNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQYVWESVADSSSYLIREETDPDNILRRGTQITLYLREDDKYEFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEVEEDEPVKEGEEGEPKKKKTTKTEKYWDWELANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPLNNEDVTNPKTKNIRLYVKRVFISDDFDGELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENKEDYKKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKNEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLIQKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGDEDEVKDREAKQEFNLLCDWIKQQLGDKVAKVQVSNRLSSSPCVLVSGKFGWSANMERLMKAQALGDTSSLEFMRGRRILEINPDHPIIKDLNAACKNAPESTEATRVVDLLYDTAIISSGFTPDSPAELGNKIYEMMAMAVGGRWGRVEEEEESSTVNEGDDKSGETEVVEPSEVRAESDPWQD
What is the function of this protein?
Molecular chaperone required for chloroplast biogenesis (PubMed:12943545, PubMed:25216779).  Essential for chloroplast biogenesis and maintenance, and thus for embryogenesis (PubMed:23875936, PubMed:23382192).  May be involved in the disassembly of VIPP1 for thylakoid membrane formation and/or maintenance (PubMed:23875936).  Cooperates with TIC components and other molecular chaperones to drive transport of preproteins into chloroplasts and functions in the chloroplast stroma to facilitate membrane translocation during protein import into the organelle (PubMed:23382192).
What are the official names of this protein?
Heat shock protein 90-5, chloroplastic, AtHSP90.5, AtHsp90-5, Heat shock protein 88-1, Hsp88-1, Hsp90C, Protein EMBRYO DEFECTIVE 1956, Protein chlorate-resistance 88.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NSRR_SALG2
Sequence: MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYGVSRNHMVKIINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: MVP_CMVAS
Sequence: MAFQGTSRTLTQQSSAATSDELQKILFSPEAIKKMAAECDLGRHHWMRADNAISVRPLVPEVTHGRIASFFKSGYDAGELCSKGCVSVPQVLCAVTRTVSTDAEGSLRIYLPDLGDKELSPIDKQCVTLHNHHLPALVSFQPTYDCPMETVGNRKRCFAVVIERHGYIGYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNMGSSQYVLTDSKINQNARSESEELNVESPPAAIGSSVASRFESFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: URED_PHOLL
Sequence: MTSTRLPQNIGEACQQANNLGVNAPELARFQDEPPQMASGDVGKSGYLRLGFARRGDRSILAQMKRRVPYLVQRALYWDEALPQMPCVFMISTSGCILQGDRLALDIHVAPEAFGHVTTQSATKIHSMENNYAAQVQTIQIEQGGYLEMMPDPVIPHSGSRFITDTQITIHPTATLIYSEIIMSGRKYHLADQGFKFDVYSSRITATDFDGKILFTERYVLEPKKQSLNSVGVMGPFHVFGNVILLTPQLHHDRILARMAPQYDAETGIASGTSRLPHQCGLIFKVLGKETYQVKAGIRLFWRIAREEILGVTLPEPFIWR
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_CUPNH
Sequence: MTQRVRTRFAPSPTGFIHLGNIRSALYPWAFARRMKGDFILRIEDTDVERSSQEAVDVILESMAWLEMDIDEGPFYQMQRMDRYREVVAQMVESGLAYRCYMSTEELDALREAQRERGEKPRYNGFWRPEPGKVLPEPPAGVDPVIRFKNPIGGSVVWDDAVKGRIEISNDELDDLVIARPDGTPTYNFCVVVDDLDMKITHVIRGDDHVNNTPRQINIIRALGGTPPVYAHLPTVLNEQGEKMSKRHGAMAVTGYRDEGYLPEAVLNYLARLGWAHGDAEIFSREQFVEWFDLEHLGKSPAQYNPEKLAWLNNHYIKVGDNQRLATLTQPFIEALGGKVEGADLAGVVALVKDRANTLKEVAQAALLFYRGEPQADAALKAEHLTPEIQPALAALANQLAALPEWKREAISATFKAVLAEFGLKMPKLAMPVRLLVAGQLQTPGIDAVLELFGRDTVLRRLAAAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_EXISA
Sequence: MSKITEVVESIALPIVERENMELVDVEFVKEGPDWFLRVYIDKPGGVDLDDCVNINEQLSEKLNETDPIEQAYYLDVSSPGAERPLKKPSDFERAVGKNVYMKTFAPIDGAKEFEGILTAYDGETVVIETRIKTRKKAVSLPVDKIAQARLAVTFS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP1_ORFN2
Sequence: MAPPVIEEYLGSRPSMERCVLLRAQRRNMTRVLNFDRKLFLSLVVKSRRRFFKKLGGSEKEIAARIEEYFSRQRRLEKLGQILTVLELQSVIVSEFTRTLGSLTTPTPAINAAVRRVDAPRARALASRALNSYAVLPPPEEAAPMARHKHSDLVEVVKRLVKEHLRRHNKRCVCYGSYALHLLNPEIEYGDIDMVQTNARPFLINLAFLIYFVTGRQTVLLRVPYLKNYVVLQDEEGGHILDSFNVRQATLRALPTLLVDNIYVLHPFVQLMAMLKMFSQTDRIRDLADNFDKARARMETLLAFALEELGEAPADGRTPLPCAFLPPEGGASRVLEADARALDCGFARAVVFLDEPALVQTLLDMGVQDDEIVDFESVSNSAFLVRDNTLFTYFSNTVLMDGDAVHDLSRRGVSAHIVMFLLLTRHPAAEGAVRSMLGSLVSDARPVTSVVERERKTGTHGVIDIAKNVITH
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: COX5A_CANLF
Sequence: SHGSHETDEEF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DCTA_ECO57
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDALNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the aerobic transport of the dicarboxylates fumarate and malate and to a lesser extent succinate, from the periplasm across the inner membrane.
What are the official names of this protein?
Aerobic C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SH21C_MOUSE
Sequence: MDLPYYHGCLTKRECEALLLKGGVDGNFLIRDSESVPGALCLCVSFKKLVYNYRIFREKNGYYRIETEPSTPKTIFPNLEELISKFKTPGQGMVVHLSNPIMRSGFCPGARRLNLEANVYENTDEEYVDVLP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family.  In SLAM signaling may cooperate with Sh2d1a/SAP.  Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through Cd244/2b4.  However, conflicting results are reported which may reflect the use of different strain backgrounds.  Proposed to act as an inhibitor of Cd244-mediated NK cell function including cytotoxicity and IFN-gamma production, the latter found also by triggering Klra4 and Klrk1 next to Cd244 (PubMed:16127454).  Seems to positively regulate Cd244- and Cd84-dependent NK cell functions implicating Cd244-mediated phosphorylation of Vav1 (PubMed:20962259).
What are the official names of this protein?
SH2 domain-containing protein 1B2, EAT-2-related transducer, ERT, EAT-2B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_HYDCU
Sequence: MKIVGLPTLSDNYTWVIQSENADDKRAWIVDPGESQKVIHYFEENQLQLDGILLTHHHYDHTDGIMGVMDALGEVAIVSNAQGPFKPVTHPVKEGDQVQVLNETFQVIETPGHTDEHICFYHPEALFSGDTLFTGGCGKIWQNPPEQMAESLLKLRALNDDCMVYCGHEYTYANLNFAKIAEPNTPAILDRLAEVKTNTQRNIPCVPARLGLEKQTNPFLRFDHPPLMQTLMERQAQPNESVSTLFATLRAWKDELDQTNILEAGLND
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DPO4_LISMO
Sequence: MDTSRKIIHIDMDAFYASVEQRDHPEFRGKPLIIGGDPNKRGVVATCSYEARKFGVHSAMPTRQAAKLCPNGIFIHGNMAHYVEVSNQIREIFSRYTDIIEPLSLDEAYLDVTENKKGMKSATMVAREIQQTIYQELGLTASAGVSFNKFIAKIASDFKKPAGITVVTPEEAEAFLEQIPVTKFYGVGKVTAEKLHRLGIETGADLKKWSEWDLIRELHKHGYHLYRHVRGRSNNIVNPHRDRKSVGKETTFEFNVLDSRVLEQSLMQFAKKVEERLIKLQKHGKTVVLKLRYSDFTTITKRLTLNEYTNDASQIYQAAALLLIESYTGQDSIRLIGLTVTNLKPVYFENLRLEGL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_HELPJ
Sequence: MIKEGFLIKTPKKLIALLGPSGSGKSALSIELAQELDAEIFSLDSLSIYEDINIASAKPSLKERKNIKHYALDYLNIDEKNNASLFKTLLEDAMRVSSKEILLIVGGSSFYLKSILEGLSGMPKLSDEEVVKIEREIATLSNPYIFLKSIDPNMAFKIHPNDTYRIHKALEIFYATHTPPSEYFKANPKKPFEHAISLFALSVEKNALANNIKQRTKSMLDCGLIEEIKALYIKYPKDSQPFKAIGVKESVLYLEKRLTLKELEEAIISNTMKLAKRQNTFNKTQFNNLYMGSVGEIRHAILKHSKSDTRER
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YCF3_NOSP7
Sequence: MPRTQKNDNFVDKSFTVMADIILKILPTNKKAKEAFVYYRDGMSAQAEGEYAEALEYYEEALTLEEDTNDRGYILYNMGLIYASNGDHNKALELYHQAIELNPRLPQALNNIAVIYHYQGEKEKEAGDNEAGEALFDQAADYWIRAIRMAPNNYIEAQNWLKTTGRSQIDVFF
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RL18_RICRO
Sequence: MRSAKLKFEKRRSRIRHKISKTSNRVRLSIFKSGRHIYAQIIDDSKSITIAAASTLDEKRKKSHCNIEHAIKVGEEIAKKAYAAGIKDVVFDRGGYKYHGVVKALADAAREKIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.