PharMolix/UniProtQA huggingface dataset:
Protein: YKG6_CAEEL
Sequence: MGRRHGWADEFRTFFPTLWLILAPLILSPLLFFGQEGKCAFVILTMSCYWVAEVVPLAVTSFIPMIALPFLGIVSIKEVAPKYFADTNIVFFNSLMLSLAVEECQLHKRIALKMLTYVGTRPHWLMAGFMIITSFISLWISDTACCALMAPIAYALLEEIMIPKMRPEEKENEIEVMKIFDKEDPEEKEKKKLDTSRLSVRDRGICKCMMLLVAHASLIGGTGTINSTGPNLIFRDNIEKNFPNEDHGISYLSWMAFAIPPMIFYMFSSWFIVQLQFLGPRHLMGMFREPTETEKQEEEVAKRAVWKSYDQLGPMTWAEKSTLVIFVLAVLSWVSSDPKVIPGWSDLFRKGYVTDSCSGLVAVFLLFIWPKKKPDFRIFRKDKSRPSVRQEPLIDWDCVRRRFPWSIILLLGAGFAISDAVRVSGLSSLIACSLNSTISKMPFFVMQIILSIVVVVMTEFSTNSATASIFIPISFKMAEAVGAHPLYFSIPTAIGPSFSFMLPMATPANAIVYETKTIRMIDMVSCGVFLNIFCIAITAINMNTWAFWLFNMGTYPDYALRHATNMTGNSSQCF
What are the official names of this protein?
Uncharacterized transporter B0285.6.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ILVC_PSE14
Sequence: MKVFYDKDCDLSIIQGKKVAIIGYGSQGHAQACNLKDSGVDVTVGLRKGSATVAKAEAHGLKVTDVASAVAAADLVMILTPDEFQSQLYKNEVEPNLKKGATLAFSHGFAIHYNQVVPRADLDVIMIAPKAPGHTVRTEFVKGGGIPDLIAVYQDASGNAKNVALSYASGVGGGRTGIIETTFKDETETDLFGEQAVLCGGTVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAESRQAMRNALKRIQDGEYAKMFISEGATGYPSMTAKRRNNAAHGIEIIGEKLRSMMPWIAANKIVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GRIR_STRM4
Sequence: MRFQVEREVLAEGIGWVARGLAVRPSVPILSGVVVNAEGDTLTLSGFDYEVSTRVELKANVEESGTVLIPGRRLADIAKVLPDVPIEFNVDQTKVYVQCDSNSFVLNALPLDEYPTLPKLPTVCGSVEGDQFARAVSQVAVVASRDDALPVLTGIGVNFDGEIMKLNATDRYRFAIRELAWKPEGTPSSSSVLVPARTLLDFAKSLNKGDLVKIALSDEGNLLGLHAGTRQMTCRLLEGTLPDYEKLFPKEFTSFGAVEVSRLVEALKRVSLVLERNSSVALDFTDGELVLQAGGADDDRATSRMAASLEGESIDIAFNPSFLLDGLTNLDASWAQFSFTSSNGKAVIMGKSSVDAEADTSARYLVMPVRFHR
What is the function of this protein?
A homolog of the beta sliding clamp protein encoded within the biosynthetic cluster for griselimycin synthesis (PubMed:26045430).  Upon expression in S. coelicolor A3(2), which is susceptible to this antibiotic, confers resistance to griselimycin (PubMed:26045430).  The beta sliding clamp confers DNA tethering and processivity to DNA polymerases and other proteins (By similarity).  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA (By similarity).  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity (By similarity).  The beta chain is required for initiation of replication as well as for processivity of DNA replication (By similarity).
What are the official names of this protein?
Beta sliding clamp homolog GriR, Beta clamp GriR, Sliding clamp GriR.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_CHLTA
Sequence: MAENRRMKKVNAMLREAIAKVILKDVKHPKISNRWITITRVSLSRDLQSACVYVSIMPHENSQEETLAALKASAGFIAFQASKDLVLKYFPDLNFYLEDIFSPQDHIESLLLKIAEQDKKTNP
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_AROAE
Sequence: MTEDKDAPLREDIRLLGRVLGDTVRDQHGEAAFALIERIRQTSVRFRRDDDNAARLELEGILDALSREQTIEVVRAFSYFSHLSNIAEDQHHIRRSRAHLIAGSAPREGSVAHALVRALASGLPPARLAAFFDTALISPVLTAHPTEVQRKSILNCETDIAHLLDARDRMTLTPEERQESDEALRRTVLTLWQTRMLRPAKLSVVDEVANGLSYFDATFLRELPHLYANLEDQLVSRDPALAGLELPAFLQVGSWIGGDRDGNPFVTADVLERTLAMQAGAVLGFYLDELHALGARLSLALGLVTASDALLALAARSPDHSPHRNDEPYRRAISGIYARLAATHHALLGTEPPRHPVAVAEPYAAVAELADDLDVIHRSLVANGSAALARGQLRRLRRAVRVFGFHLAPIDLRQNSEVHERVVAELLATARTGTDYATLDEAARVELLIEELATPRPLASPHVRYSDETEGELAIFRTARAAHRRYGGPAIPNCIISKTDDVSDLLELALLLKEAGLLRPHERALDVNIVPLFETIEDLANAPSVMDRLFALPGYMNLLAASRDRTHEVMLGYSDSNKDGGFLTSGWALYKAEIGLIEVFARHGIRLRLFHGRGGSVGRGGGPSYEAILAQPGGAVQGQIRLTEQGEVIAAKYGNPEVGRRNLEVIVAATLEASLLADRAPAPRVEFLDTMQALSDVAFAAYRGLVYDTEGFERYFWESTVISEIAELNIGSRPASRKKGTRIEDLRAIPWVFSWSQCRLMLPGWFGFGSAVKTWLAAHADDGIARLQAMHREWSFFAALLSNMDMVLAKTDLAIASRYAGLVKDVNLRDAIFERIRNEWHDTVDALLAITGQRELLDGNPLLKRSIRNRFPYLDPLNHVQVELLRRHRETHDDARIRLGIHISINGIAAGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: OBG_ECO7I
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVKNARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_BACLD
Sequence: MKSYVAVFIGGAIGSLLRYAVNLLGGTAVFPWPTFIENTSGSLLLGLLTGFFAARAKKPLVQLCLGTGFCGGYTTMSAFSKETVLLLQSAAHIGVLYLMASLACGVCFAFLGIVIGKKVSGAAGKEKERYQS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_SCHPO
Sequence: MDLVNHLEDRLLFAVPKKGRLYESCVNVLKGSDIKFRRNPRLDIALVQNLPIALVFLPAADIPRFVGTGRVHLGITGQDQIAEARLRIGDKLKIEELVDLQFGGCKLQVQVPESGDITSVDQLVGRRIVTSFEYLVAEYFDKVEKKAKSEGKVDSGIKTEISFVSGSVEASCALGIADAVVDLVESGETMRASGLKPIETVMSTSAVLVRSSNCSSELEPLLQTIITRIRGYIIAQQYVLVNYNVNREHLPVVLKITPGKRAPTITTLDEPGWVAVSSMVVKKEVAQVMDKLSQNHAHDILVLSIDNSRP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_SYMTH
Sequence: MIKPSLDQLMHLVDSKYTLVILAARRARDLQDGKHQMVESKSNKPVTIALEELAAGKLFFERGKPTPLG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: B2MG_CALAU
Sequence: MASSVVVALLVLLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPSEKDEYACRVSHVTFSTPKTVKWDRNI
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPE_PSE14
Sequence: MTAPTDLSPTLQLACDLIRRPSVTPVDADCQAVMMQRLGNAGFKLEPMRIEDVDNFWATHGTTDGPVLCFAGHTDVVPTGPVENWQNDPFDALIDEHGMLCGRGAADMKGSLAAMLVAAERFVADHPNHKGSVAFLITSDEEGPAHHGTKAVVERLAARKERLDWCIVGEPSSTTLVGDVVKNGRRGSLGATLTVRGKQGHVAYPHLAKNPIHLAVPALAELAAEHWDHGNDFFPPTSFQISNLNAGTGATNVIPGDLVAVFNFRFSTESTVEGLQQRVAAILDKHELDWHVNWALSGLPFLTEPGALLDAVSSSIKSVTGRDTKASTSGGTSDGRFIATLGTQVVELGPVNATIHQVNERILASDLDVLTEIYYQTLVKLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TRMA_STUS1
Sequence: MPLPQLDPAQYAAQLAEKAARLEELLAPFDAPAAEVFDSPREHYRLRAEFRLWREGGQRHYAMFEQGDKHKAILIDDFPIASRRINELMPQLKAAWQASEVLSFKLFQVEFLTTLSGDALITLAYHRPLDEAWQAEAEQLAADLGVSLVGRSKGKRIVIGRDYVEEQLVVAGRSFRYRQPEGAFTQPNGEVCQKMLNWAHEALGERDDDLLELYCGNGNFTLPLATRVRRVLATEISKTSVNAALANIEDNGLDNIELVRLSAEELTQALNEVRPFRRLAGIDLKSYSFGSVFVDPPRAGMDPDTCELTRRFERILYISCNPETLAQNIAQLADTHRIERCALFDQFPYTHHMEAGVLLVRR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: UPPP_ECOUT
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_STRPM
Sequence: MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQLDIGTAKATQEEQEAAVHHLTDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIRALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEHYPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAITAPDYPQVVHDRVRDFLGQKEKS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: Y1494_BURP0
Sequence: MLSLAKIAALFVLTAVAEIVGCYLPWLVLKAGKPAWLLAPAALSLALFAWLLTLHPAAAARTYAAYGGVYIAVALAWLRIVDGVPLSRWDVAGAALALAGMSVIALQPRG
What are the official names of this protein?
UPF0060 membrane protein BURPS1106A_1494.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC1_ORYSI
Sequence: MIDQYKHQQLQIGLVSPQQIKAWANKTLPNGEVVGEVTRPSTFHYKTDKPEKDGLFCERIFGPIKSRICACGNSRASGAENEDERFCQKCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKGLPSYIANLLDKPLKKLEGLVYGDFSFARPSAKKPTFLRLRGLFEDEISSCNHSISPFFSTPGFTTFRNREIATGAGAIREQLADLDLRIILENSSVEWKELEDEGYSGDEWEDRKRRIRKVFLIRRMQLAKHFIQTNVEPEWMVLCLLPVLPPELRPIVYRSGDKVVTSDINELYKRVIRRNNNLAYLLKRSELAPADLVMCQEKLVQEAVDTLLDSGSRGQPTRDGHNKVYKSLSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPLEIAIKLFQLFVIRDLITKRATSNVRIAKRKIWEKEPIVWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPTLVEGRTICLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEARLLMFSHMNLLSPAIGDPICVPTQDMLIGLYVLTIGNRRGICANRYNSCGNYPNQKVNYNNNNPKYTKDKESLFSSSYDALGAYRQKQICLDSPLWLRWKLDQRVIGLREVPIEVQYESLGTYREIYAHYLVVGNRKKEIRSIYIRTTLGHISFYREIEEAIQGFSQAYSYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SCYL1_RAT
Sequence: MWFFARDPVRDFPFELNPEPPEGGPPGPWVLHRGRKKATGSAVSIFVYDVKPGAEEQTQVAKAAFKRLKTLRHPNILAYIDGLETEKCLHIVTEAVTPLGTYLKARAEAGGLKEQELSWGLHQIVKALSFLVNDCNLIHNNVCMAAVFVDKAGEWKLGGLDYMYSAQGNGGGPPNKGIPELEQYDPPELADSSSRAVKEKWSADMWRLGCLIWEVFNGSLPRATALRNPGKIPKSLVTHYCELVGANPKVRPNPARFLQNCRAPGGFMSNRFVETNLFLEEIQIKEPAEKQKFFQELSKSLDSFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFKVGKFLSAEEYQQKIIPVVVKMFSSTDRAMRVRLLQQMEQFIQYLDEPTVNTQIFPHVTHGFLDTNPAIREQTVKSMLLLAPKLSETNLNVELLKHFARLQAKDDQGPIRCNTTVCLGKIGSYLSASTRHRVLTSAFSRATKDPFAPSRVAGVLGFAATHNLYSMDDCAHKILPVLCGLTVDPEKSVRDQAFKTIRSFLSKLESVSEDPTQLAEIEKDVHAASSPGTGGAAASWAGWAVTGVSSLTSKLIRTHPTPVPSEAAVPQRPVPEGDPAPAPAPASATPATSGHRETQEEDKDAAEDSATADRWDDEDWGSLEQEAESVLAQQDDWSTKGQGNRAGQVSHSDHKSLDSHWSSWEVEGSWDQGWQEPSSVEPPPEGTRLASEYNWGGAEPSDKGDPFAALSVRPSTQPRPDPDSWGEDNWEGLEAESRQVKAELARKKREERRREMEAKRAEKKATKGPMKLGARKLD
What is the function of this protein?
Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum.  Involved in the maintenance of the Golgi apparatus morphology.  Has no detectable kinase activity in vitro.
What are the official names of this protein?
N-terminal kinase-like protein, SCY1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Localized to the Endoplasmic reticulum-Golgi intermediate and cis-Golgi in an ARF1- independent manner.
Protein: TRPA_MYCTA
Sequence: MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVESGCDIIEVGVPYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASEEHRLDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAPELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEGLPRLRALTGELAAGVRLGMSA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL22_COXB1
Sequence: MEVAAKLKYARISAQKARLVADQVRGLGAEQAVNLLRFSNKKAAALMKKVLNSAIANAEHNEGADIDELKVSTVMVDEGPSARRFHARARGRANQILKRTCHITVKVSDSQVEND
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: UBIG_XYLFM
Sequence: MPSSYDRVSKNYRQSELDKFAAFTSGWWDPHGPQKPLHALNPVRLDYISKRVSLSGARVLDVGCGGGLLSEALARQGAHVTAIDLAPELIKAARLHGLESGIQVDYRIQAIEDLLAEQPAPFDAIACMEMLEHVPDPAAIVDACAHLLKPGGRLFVSTINRTLAAFMLAVVGAEYVVRLLPKGTHQYKDFIRPAELAAWLRHAGLHLEDVSGMRYEPWRNRARLTARTDINYLACAISPEASHATE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: THII_ALKCK
Sequence: MKMDHILVRYGELALKGKNRGHFEKLLLANIRHVLKPFPKVQAKRTFGRIVVELNSTDHEPVAAALANVFGIQSYSLALRVENELEAMQKGALFMLTQHPDAKTFKVSARRAYKLFPIDSQSLNHKIGSYVLKAFTGELAVDVHHPDVNVVVDVRESGTYITAGVYAGAKGLPVGSSGKVLHLLSGGIDSPVAAHMLMGRGAEVEMLHFHSPPYTNERAKQKVIDLTRELTKFGRTITLHFVPFTDIQTHIHKEVPSSYEMTIMRRMMLRIADRIARERGILAISNGESLGQVASQTLASMNTINEMTNLPVLRPLLAMDKETTIAYAKRIGTYETSILPYEDCCTIFLPTDSKTKPKRDRSAHFEQYVQVEEKCREAIAGIESLEVTGAHTSPTLDQLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_RHIE6
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVIAGNIIVRQRGTQWHPGSNVGLGKDHTIFALTAGNVDYRTKANGRVYVSVMPKAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS3_ACHLA
Sequence: MGQKTNPNGLRLGIIRTWESKRYADQKDVPALIKEDALIREFLNENFSKAGVSQIEIERVKAKSKERVTIKLYVSKPGIALGKEASVKNKAVSNLEYLTKKEVILNIIEVRRPEKVAVLVAQSIAEQLENRASFRRAQKMAIQRALKSGAKGIRTLVSGRLGGAEMARSEGYSEGRVPLHTLRADVDYATAEASTTYGILGIKVWIYHGEVLPGQSILDTRKPFEAGNQRRGQKRRPRNDQPVKDLNKEKEIARRTNYYVNAKKN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: BXA3_SAMCY
Sequence: MRTQVLFLVLEVAAMASGDDTPHVYCGRRLAIMLSYLCDNQYLMKRTPYTSSESEGYGWRWLAPQRARQLAGARGKRQGIAEECCNKPCTEDELLGYC
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin A-3 homolog.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMN6_EDWI9
Sequence: MPHPPSAALSLPRNGFTLKRFFVAHDRCEMKVGTDSIMLGAWLPLRGDERHILDIGSGSGVLALMMAQRSTAQVDGVEIEPGAATQGQENFLASPWPTRLTMHTLSLQAFSAGCGRRYDLIVSNPPYFAPGVACRTAARATARYTDSLDHAALLRHAAELSCEDGRLALVLPVEAAESVVSKGMTHGWHLLRRTAVRDRADKPVRRTLLLFGRIPAAVQSNTLDIRDDSSEYSCIFRNMTKDFYLFF
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_ANADE
Sequence: MADRNDPLLRTPAWRALETHLAEVRPLHLRELFARDPGRGDRLAAEGAGLYLDYSKQRVTEETVRLLVALAEARGLPGRRAAMFRGEKVNATEGRAALHVALRAPRGERIEVDGKDVVPEVHAVLDRMAAFAEQVRSGAWTGFTGRRIRTVVNVGIGGSDLGPAMAYRALRAYTTREIAFRFVSNVDGTDLAEAVRDLDPAETLFLVASKTFTTLETMTNAASARAWLLAALGDERAVARHFVAISTNEAEVRRFGIDPANMFGFWDWVGGRYSMDSAIGLSTMIAVGPGGFRELLAGFRAMDEHFRDAPLERNLPALVGLIGVWNASLLGAETVAVLPYDQYLDRFPAYLQQLTMESNGKRVTASGAPVEGHGTGAIYWGEPGTNGQHSFYQLLHQGTHLVACDFIGFCRTLNPLGRHHDLLMANLFAQGEALAFGKTAEEARAEGTPEALVPHRTFPGNRPSSTILADRLGPGTLGALVALYEHAVFTQGVIWDVDSFDQWGVELGKVLANRIVKELEAPADPALAHDGSTNALIRRYRARRGGSASS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_NOCSJ
Sequence: MCPEQPHDTRAERDEMSEQTQQAAQPAETAAYDVRAIQDKWLPVWERLDPFRADDSSPREKKYALTMFPYPSGDLHMGHAEVTALHDVVARYWWQRGYEVLNPMGWDSFGLPAENAAIRNDEHPATYTYANIETQYESFKRYAVSFDWSRRLHTSDPEYYRWTQWLFLKFRERGLAYRKSSPVNWCPNDQTVLANEQVVDGRCERCGAEVTKRELTQWYFKITDYAQELLDRLDDLEPTWPARVVTAQRNWIGRSEGAHVDFVVDGRDEPITVYTTRPDTIFGTTFMVVAVDSPLAAELVTDAQRPAFEAYREEIRKETEIERLSTDRPKTGVDLGVTATNPVTGTQIPVWATDYVLADYGTGAVMGVPGGDQRDWEFATEMGLDIVRTTQTPEGFDGEAYHGEGPAINSPAPGADAPLDINGLPVDEAKRATIEFLEQQGTGAGAVNFRLRDWLLSRQRYWGVPIPIIHCDACGEVAVPYDQLPLELPELRGADLKPKGVSPLAAAEEWVNVACPECGGAATRDSDTMDTFVDSSWYFLRYCSPDYTEGPFDVEKAKAWMPADIYVGGVEHAVLHLLYARFFTKVLRDMGMLEVDEPFAAQLNQGIVINQGKKMSKSLGNGVSLGDQLAEFGVDAVRVTLVFAGPPEDDIDWADVSPAGALRFLQRAWRLSGDVTSEAGTPAAGGDVALRRVTARTVHDAAELIESYRFNVMVARVMELVNATRKAIDGAPGPADPAVREATETVAILLSLVAPYVAEEMWERLGHEPTVARVGWPEVDPALLVEEQVTAVVQIQGKVRARLEVAPDISEADLEQLAMADPAVVRAIDGRPVRKVIVRAPKLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.