PharMolix/UniProtQA huggingface dataset:
Protein: ZKSC4_HUMAN
Sequence: MAREPRKNAALDAQSAEDQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFKHESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLTPGWTQLDSSQVNLYRDEKQENHSSLVSLGGEIQTKSRDLPPVKKLPEKEHGKICHLREDIAQIPTHAEAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHGDKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSHVGKKTLSQ
What is the function of this protein?
May be involved in the transcriptional activation of MDM2 and EP300 genes.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 4, P373c6.1, Zinc finger protein 307, Zinc finger protein 427.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: KS1_ISOER
Sequence: MSLLLSNSVLVGPKFRSSRISHASASLDIGLQRATSPQNASVPTCFEETKGRIAKLFHKNELSVSTYDTAWVAMVPSPTSSEEPCFPACLNWLLENQCHDGSWARPHHHHMLKKDVLSSTLACILALKKWGVGEEQINRGLHFVELNFASATEKGQITPMGFDIIFPAMLDNARGLSLNLQLEPTMLNDLIYKRDLELKRCNQSNSAEKEVYWAHIAEGMGKLHDWESVMKYQRKNGSLFNCPSTTAAAFTALRNSDCLNYLCLALEKFGSAVPAVYPLDIYSQLCTVGNLERLGISRYFLTEIQSVLDETYRSWLQGDEEIFMDASTCALAFRTLRMNGYNVTSDPITKILQECFSSSFRGNMTDNNTTLEIYRASELILYPEERDLVQHNLRLKTFLEQELSSNGFIQSCQLGRNINAEVNQAIEYPFYAIMDRMAKRKNIENYNIDNTRILKTSYRSPNFGNKDFLSLSVEDFNRCQVIHREELRELERWVIENRLDELKFARSKAAYCYFSAAATIFSPELSDARMSWAKNGVLTTVVDDFFDVGGSVEELKNLIQLVELWDVDVSTQCCSPNVQIIFSALKHTICEIADKGFKLQGRSITDHIISIWLDLLYSMMKETELGIDKSFPTMDEYMSNAYVSFALGPIVLPALYLVGPKLSEEMVNHSEYHTLFKLMSTCGRLLNDIRGYERELKDGKISAVSLYIMNNGGEITTEAAISEMRSWIERDRRELLRLVLEENKSVLPKACKKLFWHMCTVVHVFYSKDDGFTSLNLHGVVNAIINEPIVLNQF
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities, and in the production of gibberellins phytohormones (PubMed:30496917).  Catalyzes the conversion of ent-copalyl diphosphate (ent-CPP) to ent-kaurene (PubMed:30496917).
What are the official names of this protein?
Ent-kaurene synthase 1, chloroplastic, IeKS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FTSH1_ARATH
Sequence: MASNSLLRSSSNFFLGSHIIISSPTPKTTRKPSFPFSFVSRAKYQITRSSQDENSPNGKPNSPFSSQVALAAILLSSISSSPLALAVVDEPASPSVVIESQAVKPSTPSPLFIQNEILKAPSPKSSDLPEGSQWRYSEFLNAVKKGKVERVRFSKDGSVVQLTAVDNRRASVIVPNDPDLIDILAMNGVDISVSEGESSGNDLFTVIGNLIFPLLAFGGLFLLFRRAQGGPGGGPGGLGGPMDFGRSKSKFQEVPETGVSFADVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARAVAGEAGVPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGAGMGGGNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVKILQVHSRGKALGKDVDFDKVARRTPGFTGADLQNLMNEAAILAARRELKEISKDEISDALERIIAGPEKKNAVVSEEKKRLVAYHEAGHALVGALMPEYDPVAKISIIPRGQAGGLTFFAPSEERLESGLYSRSYLENQMAVALGGRVAEEVIFGDENVTTGASNDFMQVSRVARQMIERFGFSKKIGQVAVGGPGGNPFMGQQMSSQKDYSMATADIVDAEVRELVEKAYKRATEIITTHIDILHKLAQLLIEKETVDGEEFMSLFIDGQAELYIS
What is the function of this protein?
Part of a complex that function as an ATP-dependent zinc metallopeptidase.  Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH 1, chloroplastic, AtFTSH1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Protein: KLF9_MOUSE
Sequence: MSAAAYMDFVAAQCLVSISNRAAVPEHGGAPEAERLRLPEREVTKEHGDPGDTWKDYCTLVTIAKSLLDLNKYRPIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGSAPSPLSLLHSGVASKGKHASEKRHKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTVFHPSMIKRSKKALACPL
What is the function of this protein?
Transcription factor that binds to GC box promoter elements.  Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box.  Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation.
What are the official names of this protein?
Krueppel-like factor 9, Basic transcription element-binding protein 1, BTE-binding protein 1, GC-box-binding protein 1, Transcription factor BTEB1.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB_COLP3
Sequence: MIEADRLIEPIASVEDERVDRAIRPKMLQDYTGQQHVKAQMEIFIPAAKNRGEPLDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDILFIDEIHRLSAVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGALTSPLRDRFGIVQRLEFYNVADLSTIVSRSAHFLNLTIDEEGAFEVARRSRGTPRIANRLLRRVRDYADIKSHGVVNQQTAAAALDMLEVDSEGFDIMDRKLLHAIIDKFMGGPVGLDNVAAAIGEERETIEDVIEPFLIQQGFLQRTPRGRIATDRAYQHFGITKDQTKD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ANMK_ECO5E
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVKALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ATPE_RHILO
Sequence: MAEAFKFELVSPERLLVSEQVESVVIPGAEGEMTVMAHHAPVMTTIKPGVVTVKTASGGEERYVVFGGFADIVPAGCTLLAESAVAVKDVDRADLARRIQEAKEDAADAKDDQARSKAEQFLSQLTTLEGAILPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MATN1_MOUSE
Sequence: MKVTSGPAFALCSLLLLLLLLLQVPDSLSLVPQPRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGLVNYASTVKPEFPLRAHGSKASLLQAVRRIQPLSTGTMTGLALQFAITKALSDAEGGRARSPDISKVVIVVTDGRPQDSVRDVSERARASGIELFAIGVGRVDKATLRQIASEPQDEHVDYVESYNVIEKLAKKFQEAFCVVSDLCATGDHDCEQLCVSSPGSYTCACHEGFTLNSDGKTCNVCRGGGSGSATDLVFLIDGSKSVRPENFELVKKFINQIVDTLDVSDRLAQVGLVQYSSSIRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAARKAKDLGFKMFAVGVGNAVEEELREIASEPVADHYFYTADFKTINQIGKKLQKQICVEEDPCACESILKFEAKVEGLLQALTRKLEAVSGRLAVLENRII
What is the function of this protein?
Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage.  It binds to collagen.
What are the official names of this protein?
Cartilage matrix protein, Matrilin-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SULA_ECOSE
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: SURE_METPB
Sequence: MRILVTNDDGIHAPGLETLQGIARELSDDVWVVAPEYDQSGVSHSLSLNDPLRLRQVSEKRFAVKGTPSDCVIMGVSHILKDHRPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIRAIALSQAYGAGGRANLKWSCAAAHGAAVIRKILEIGIEPGILVNVNFPDCEPEEVQGVAVSAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRIAVTPLRLDLTDEPELTRFAAAFRA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O17H_CONCN
Sequence: CKGKGAPCTRLMYDCCHGSCSSSKGRCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This toxin blocks N-type calcium channels (Cav2. 2/CACNA1B) with high potency.  Unexpectedly, it does not show any blocking activity at amphibian neuromuscular junction.  In vivo, when intracerebroventricularly injected into mice causes shaking activity, and, at higher doses, causes mild tremors.  When injected intramuscularly into fish, it causes paralysis, and, at higher doses, causes death.
What are the official names of this protein?
Omega-conotoxin-like CnVIIH.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEA29_ARATH
Sequence: MASNQQSYKAGETRGKAQEKTGQAMGTMRDKAEEGRDKTSQTAQTAQQKAHETAQSAKDKTSQTAQAAQQKAHETAQSAKEKTSQTAQTAQQKAHETTQAAKEKTSQAGDKAREAKDKAGSYLSETGEAIKNKAQDAAQYTKETAQGAAQYTKETAEAGRDKTGGFLSQTGEHVKQMAMGAADAVKHTFGMATEEEDKEHYPGSTTTTTATTRTTDPTHQTYQRK
What is the function of this protein?
Involved dehydration tolerance.
What are the official names of this protein?
Late embryogenesis abundant protein 29, LEA 76 homolog.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y044_PSEPF
Sequence: MLSWAITFLIIAIIAAVLGFGGIAGTATGIAKILFVVFLVMFIASFFFGRRGRG
What are the official names of this protein?
UPF0391 membrane protein Pfl01_0044.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_DELAS
Sequence: MAQKKGGGSTRNGRDSKPKMLGVKAFGGELITAGSIIVRQRGTKFHPGDNVGVGKDHTLYALVDGHVSFAVKGALSKHTVNVTAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RCNR_ECOL6
Sequence: MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_TOLAT
Sequence: MDRYAVFGNPINHSKSPFIHTLFARQTQQLLTYEKIEAPVDDFVGSIRRFFAEGGKGANVTVPFKEQAFQLVDQLSPRAKLAGAVNTLKLTDDGLLLGDNTDGAGLVQDLKYHLEELAGKKILLLGAGGACRGVIGPLLEQRPSEIVIANRTVAKAEQLAQEFAAMGKVRVSQFAELNESFDLIINGTSASLAGAMPDIPDAVIGSATVTYDMMYGSKETVFNLWAKEHGAIKTIDGLGMLVCQAAESFAVWRGIRPGTRQVIRELRRNITGA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ARLY_CAMC1
Sequence: MKKNENAHKKMWEGRFSEASSKLLEEFNASINFDKNLFEEDIAGSKAHAKMLGICGILKKDESEAIIKGLDEVLAEIRAGKFAFKIEDEDIHMAVEKRLSQIIGAELGGRLHTARSRNDQVALDFKFYVLKKNLEISSLIKELIATLTNLAKNHKDTLMPGYTHFQHAQPVSLSYHLLAYAFMFKRDFERFVSSYERNNLSPLGSAALAGTPHKIDRSIVASELGFADCTQNAMDSVSDRDYALEILFNISVFMTHASRLCEELILWSSQEFGFVSISDAYSTGSSIMPQKKNPDVAELIRGKTGRVNGNLVALLTTMKGLPLAYNKDMQEDKEGVFDSVATILSSATILNEMIKTAKFNEKNMLKATKTGHLSATDLADYLVREKNIPFRTAHFITGKAVAKAESLGLDLSELNKEQLKSVDENLDENAIKFLDLHASKEARTSKGGTANKSVEEQIQILDDWLK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGP1_ARATH
Sequence: MVEQKRYALFLATLDSEFVKKTYGGYHNVFVTTFGDEGEHWDSFRVVSGEFPDEKDLEKYDGFVISGSSHDAFENDDWILKLCDIVKKIDEMKKKILGICFGHQIIARVRGGTVGRAKKGPELKLGDITIVKDAITPGSYFGNEIPDSIAIIKCHQDEVLVLPETAKVLAYSKNYEVEMYSIEDHLFCIQGHPEYNKEILFEIVDRVLALGYVKQEFADAAKATMENRGADRKLWETICKNFLKGRVPTN
What is the function of this protein?
Involved in glucosinolate biosynthesis.  Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates.  The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis (PubMed:19483696, PubMed:21712415).  Converts phenylacetohydroximoyl-GSH to benzylglucosinolate (PubMed:19483696).  Can use the GSH conjugate of the camalexin intermediate IAN (GS-IAN) as substrate.  Required for the biosynthesis of camalexin, a pathogen-inducible phytoalexin with antibacterial and antifungal properties (PubMed:21712415).
What are the official names of this protein?
Gamma-glutamyl peptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y520_MYCBO
Sequence: MSRPQVELLTRAGCAICVRVAEQLAELSSELGFDMMTIDVDVAASTGNPGLRAEFGDRLPVVLLDGREHSYWEVDEHRLRADIARSTFGSPPDKRLP
What are the official names of this protein?
Uncharacterized protein Mb0520.
Protein: CNBL3_ORYSJ
Sequence: MLQCLEGVKQLCGVLLKCCDLDLKQPKGLEDPEILARETVFSVSEVEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPLDEKIDFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLSDEVIESIIDKTFEEADTKHDGKIDKEEWRNLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVDDT
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Calcineurin B-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: ACTMP_DROME
Sequence: MSNISSVAPPPPPPPMIVTPSTPATTKERPVGDNITTDECTWACEYPEVQKGCYLSRVCQYTPPKHCQYYSVNSIVQVGPTCGLVALSMLLGGSPTADDLLKDAIDQEYTLNGELFSAQYLFELTRKHMPGPAACQLHVGPLDCKKVKELLKAGGCLLVPYDADVNHAPCVKNGHRAHWALIVGYLVDTQDRFYVLARHGKSRNLAVWPLDTLSQSNENLKEFAQPKGYPDDEFLLPPGGIGGSLGLNERCILVNGLPKQVIHVRWS
What is the function of this protein?
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation.
What are the official names of this protein?
Actin maturation protease, Actin aminopeptidase ACTMAP.
What is the protein family that this protein belongs to?
Belongs to the ACTMAP family.
Protein: RSMG_HELAH
Sequence: MNPLLQDYARILLEWNQTHNLSGAKHLSELEPQITDALKPLEFIKDFKSCLDIGSGAGLPAIPLALEKPEVKFILLEPRMKRAAFLNYLKSVLPLKNIEIVKKRLEEYQNPLQVDLITSRAVANSSFLIEKSQRFLNDKGYFLFYKGEQLKDEIAYKDTECFICKKRIYFYKPKESLC
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFA_ECOBW
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQGA2_MOUSE
Sequence: MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHLEEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKKSGLHFRHTDNTVQWLRAMEAIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLGIAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQKELWEAKKKKEESAKLKNSCISEEERDAYEELLTQAEIQSNISTVNRMAAVDHINAVLQEGDPENTLLALKKPEAQLPAVYPFAAVMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQALESSDLVAVQNQLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSWNEIQNCIDMINNQIQEENDRMVVLGYINEAIDAGNPLKTLDTLLLPTANIRDVDPDCAQHYQDVLFYTKSQKLGDPKNVSKVLWLDEIQQAINEANVDENRAKQWVTLVVDVNECLDRKQSDHILTALKSSPSNIHNILPECANKYYDTLVKAKESKTDNESSEGSWVTLNVQEKYNYYYNTDSKEGSWVPPELCLSKESWLTGEEIEDIVEEVTSDYIREKLWSASEDLLVRFEATTLGPALREEFEARKAFLYEQTESVVKIQAFWKGFKQRQEYLHRQQVFAGNVDSVVKIQSWFRMVTARKSYLSRLRYFEDHKNEIVKIQSLLRASKARDDYKALVGSENPPLTVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHRKKLNKKKGGEIEILNNTDNKGIKSLSKERRKTLETYQQLFYLLQTKPSYLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIEDKALVINTNPVEVYKAWVNQLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRKVTDKVLGSIISSLDLLPYGLRYIAKVLKNSIREKFPDATEEELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSNQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFQEACDVPEPEEKFNMDKYTDLVTVSKPVIYISIEEIINTHLLLLEHQDAIATEKSDLLNELLESLGEVPTVESFLGEGAVDPNDPNKENTLNQLSKTEISLSLTSKYDVKDGEAVDGRSLMIKTKKLIIDVTRNQPGSTLTEILETPATGQQELEHAKDMESRAVVDSRTPEEGKQSQAVIEDARLPLEQKKRKIQRNLRTLEQTGHVSSKNKYQDILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYEDQINYYDTYIKTCVDNLKRKNSRRSIKLDGKAEPKGTKRVKPVRYTAAKLHDKGVLLGIDDLQTNQFKNVMFDIIATEDMGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK
What is the function of this protein?
Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity.  Associates with calmodulin.
What are the official names of this protein?
Ras GTPase-activating-like protein IQGAP2.
Protein: PB2_I03A1
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIIEMVPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSAVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVSGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVNICKAAMGLRISSSFSFGGFTFKRTSGSSFTKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGVLPDMTPSTEVSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTILGKDAGALTEDPNEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RR8_ORYSA
Sequence: MGKDTIADLLTSIRNADMNKKGTVRVVSTNITENIVKILLREGFIESVRKHQESNRYFLVSTLRHQKRKTRKGIYRTRTFLKRISRPGLRIYANYQGIPKVLGGMGIAILSTSRGIMTDREARLNRIGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYH_SACEN
Sequence: MSTFNAPKGIPEYFPPESAAFLAVRETLADAARRAGYGYIELPLFEDTTLFARGVGESTDVVSKEMYTFADRGGRSVTLRPEGTAGVTRSVIENGLDRGQLPVKLYYSGAFFRYERPQAGRYRQLQQLGVEAIGVDDPALDAEVIAIADEGYRRLGLTGYRIELTSLGDETCRPSYRAKLQEFLRGLPLDEDTRKRAELNPLRVLDDKRPEVRELLADAPLMVDHLSVEAKEHYEQVKTHLSDLGVAFTENPRLVRGLDYYTKTTFEFVHDGLGAQSGIGGGGRYDGLMAELGGQELSGVGFGLGVDRTLLACQAEGLAVGDQARCDVYCVPLGEAAKRRLVTIAGGLRGAGVRADVAYGGKSLKGAMKGADRSGARFALVLGERDLEAGSAQLKDLASGEQRPVPLDDAVAAVREALQP
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2550_NITMU
Sequence: MQQFPRLARVGLGFRRELIPALKSGVPATIDFFEIAPENWIDLGGGAARDLLFFTERYPFVCHGLSLSIGGPAPLDEILLQKIRQFLDQHRVLLYTEHLSYCSDDGHLYDLLPIPFTEEAVKYVAERVRRTQDILERRIALENASFYVASPISDMSELDFIRAVLLEADCDLHLDVNNVYVNSINHDYDPVDFIRALPSDRIVYMHMAGHHKEAENLIIDTHGADVIDPVWSLLDQTYGMHGVAPTLLERDFNIPPLEQLMREVLHIALIQAQHADSGDASAT
What are the official names of this protein?
UPF0276 protein Nmul_A2550.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.