PharMolix/UniProtQA huggingface dataset:
Protein: TSAE_MYCLE
Sequence: MAEYSLRSGAVICERVEDTVALGSRLGEQLRAGDVVVLSGPLGAGKTVLAKGIAVAMDVDGPVISPTYVLARVHLPRRLGTPAMIHVDVYRLLDHRDADLVGELDSLDLDTDLAEAVVVMEWGAGLAECLAARHLDIRLERVRYSDVRIATWQWVCSRDRP
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ACTP2
Sequence: MSRTKKTRRITDIMPARKADKKPEQPKLSGGKNRKSTRYELDAKAREEKKKRKHKGLPTGSRNVDPAEQKKAAVKEVKDPRIGSRKKIPLMVEFVNKPEKGQIIKPVAMEEYKPHLSPELELEQLENNEILNQLLDEIEAGKTLSAKDQKFVDECLDRIDELMTELGIQDEDEDNGDALLRQFETMDINQFR
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: XANC_ASPFU
Sequence: MHSQTTKDEQSKDDSSNEKQDAIERRRLQNRLSQRNHRRKIRDRIAKLQERVIASELRAVATLNGWDQASPPAASMMESKPQGDFDSNPLASVSEDPAISNPPQRNVSSNLCRSCCSLLNQMPSSSSLPSPTSPLPFDLGLTNGVDSTNSSPSTLLNSSPSSSQLSPFSLDTSLSMTGLQSQNEFSFPPYPDPPGSQQYPHCPQYYVATEASLPHIMQRLGSATSHPKAIILIPHGHGYAPAPFTGANAADSTGLRSALNGNLNLQNPGRHCLRPDRSAKSSDLGTSGDWMTAPSSTPFCPLHPSQSSSLDNYQSMML
What is the function of this protein?
Transcription regulator that specifically up-regulates the gene cluster that mediates the biosynthesis of the isocyanide xanthocillin and its derivatives.
What are the official names of this protein?
Xanthocillin biosynthesis cluster transcription factor xanC, Xanthocillin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMTA_ECO57
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YESF_BACSU
Sequence: MMKQNPILITGGTGTVGSRIASRLIKLGYRVRIASRKKGALADAEYVYFNWKYASSFTPALEQVKQIYLVAPVGVFDPAPYVLPFLKEAKRLGAKRVVMQSASVVSENGPVFGALHQAVREFPEWTVLRPSYFMQNFINVQHRMSIQTEGRITTASGEGKLGFIDADDIAETAVRALIDDVPHQTHHILTGPEALSYAEAAEIIGAAAGRRVEHVSISRSELQHKMEAGGLPADYAHFMAKLDEAISHGAEHRVTDTVKRVTGKEPRSLSEFAAAHAAYWTSFWTE
What are the official names of this protein?
Uncharacterized oxidoreductase YesF.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: K1143_BOVIN
Sequence: MSKRNQVSYVRPAEPAFLARFKERVGYKEGPTVETKRIQPQLPEEDGDHSDKEDEQPQVVVLKKGDLSAEEVMKIKAEIKAARADEEPPSADGRIMYRKPVKRSSDEKHSGLSASSKKKKTKEEDEINKQDSVKKNSQKQIKNSSLLSFDNEDENE
What are the official names of this protein?
Uncharacterized protein KIAA1143 homolog.
Protein: PSAJ_CRUWA
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL10_METM7
Sequence: MIDAKSEHKIAPWKIEEVNALKELLKSTSIIALIDMMEVPAVQLQEIRDKIRDQMTLKMSRNTLMKRAIEEVAEETGNPEFAKLADYLDKGAAIIATEMNPFKLFKTLDESKSPAPVKGGATAPCDIEVKAGSTGMPPGPFLSELKAVGIPAAIDKGKIGIKEDKVVVKEGEVVSQKLAVVLSALGIKPVTVGLNVLGVYEDGVIYTESDLKIDEEEFIGKIQKAYTSAFNLSVNAVIPTSATIETIVQKAFNDAKAVSVESAFVTDKTADAILGKAYAQMIAVAGLAGDDALDEELIEKMSSGAAAPVEEAPVEEKKEEKKEEAAPAAGLGMLF
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ZFYV9_HUMAN
Sequence: MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESAVSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGDLMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASGALSSPPPTVMVPVGVLKHPGAEVAQPREQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLIPEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV
What is the function of this protein?
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor.  Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex.  Possibly associated with TGF-beta receptor internalization.
What are the official names of this protein?
Zinc finger FYVE domain-containing protein 9, Mothers against decapentaplegic homolog-interacting protein, Madh-interacting protein, Novel serine protease, NSP, Receptor activation anchor, hSARA, Smad anchor for receptor activation.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane.
Protein: CAHM2_HUMAN
Sequence: MAALIAENFRFLSLFFKSKDVMIFNGLVALGTVGSQELFSVVAFHCPCSPARNYLYGLAAIGVPALVLFIIGIILNNHTWNLVAECQHRRTKNCSAAPTFLLLSSILGRAAVAPVTWSVISLLRGEAYVCALSEFVDPSSLTAREEHFPSAHATEILARFPCKENPDNLSDFREEVSRRLRYESQLFGWLLIGVVAILVFLTKCLKHYCSPLSYRQEAYWAQYRANEDQLFQRTAEVHSRVLAANNVRRFFGFVALNKDDEELIANFPVEGTQPRPQWNAITGVYLYRENQGLPLYSRLHKWAQGLAGNGAAPDNVEMALLPS
What is the function of this protein?
Pore-forming subunit of a voltage-gated ion channel.
What are the official names of this protein?
Calcium homeostasis modulator protein 2, Protein FAM26B.
What is the protein family that this protein belongs to?
Belongs to the CALHM family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABZ_DESPS
Sequence: MSDVITPGEIDIVGILDLLPHRYPFVMVDRILSIDPGKEIVGLKNVTFNEQYFQGHFPGEPVMPGVLMLEGLAQVGCVHAFYTEPDAVGKKLAFFAGVDKARFRKPVRPGDQLIYKVQLVKEKRSIIFMSAKGYVDDQVVVQAELMASFS
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WIT1_HUMAN
Sequence: MQRRGQPLENHVALIHWQSAGIPASKVHNYCNMKKSRLGRSRAVRISQPLLSPRRCPLHLTERGAGLLQPQPQGPVRTPGPPSGSHPAAADN
What are the official names of this protein?
Putative Wilms tumor upstream neighbor 1 gene protein, WIT-1, Wilms tumor-associated antisense RNA.
Protein: LIPS_RAT
Sequence: MKPRRPISFTREITAMEPSSTSVSRPEWRPEAQQTLTDYPGSRELQEFGIPQKQSLPNEATAQQGAEFQQEQGVQQSTLLQKLLTPLAFPVPQQSFPSHKVHSDQQEATSQNGPGAGKVHTTQKELEHRDEHVGTAESGPAEPPPATEVEATSIAQAVSGPDKKLPTQTDLVSQERAEQSDPTAQQTPLVQGVKSDQGSLIESGILARLQKLAIQQPSQEWKTFLDCVTESDMEKYLNSSSKSNPPEPSGGTVIPGTLPSKQKPDCGKMSGYGGKLPHGKKGILQKHKHYWDTASAFSHSMDLRTMTQSLVALAEDNMAFFSSQGPGETARRLSNVFAGVREQALGLEPTLGQLLGVAHHFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLRALAYYAQRLLTINRPGVLFFEGDEGLSADFLQDYVTLHKGCFYGRCLGFQFTPAIRPFLQTLSIGLVSFGEHYKRNETGLSVTASSLFTGGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIEVLSSLANMASTTVRVSRLLSLPPEAFEMPLTSDPKLTVTISPPLAHTGPGPVLARLISYDLREGQDSKMLNSLAKSEGPRLELRPRPQQAPRSRALVVHIHGGGFVAQTSKSHEPYLKNWAQELGVPIISIDYSLAPEAPFPRALEECFFAYCWAVKHCELLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTTLQSSASPSRLLSLMDPLLPLSVLSKCVSAYSGTETEDHFDSDQKALGVMGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPHKTPLPATETLRPTDSGRLTESMRRSVSEAALAQPEGLLGTDSLKKLTIKDLSFKGNSEPSDSPEMSQSMETLGPSTPSDVNFFLRSGNSQEEAETRDDISPMDGIPRVRAAFPDGFHPRRSSQGVLHMPLYSSPIVKNPFMSPLLAPDVMLKTLPPVHLVACALDPMLDDSVMFARRLKDLGQPVTLKVVEDLPHGFLSLAALCRETRQAAELCVQRIRLILTPPAAPLT
What is the function of this protein?
Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters (PubMed:6643478, PubMed:9162045, PubMed:10694408).  Shows a preferential hydrolysis of DAGs over TAGs and MAGs and preferentially hydrolyzes the fatty acid (FA) esters at the sn-3 position of DAGs (By similarity).  Preferentially hydrolyzes fatty acids at the sn-1 and sn-2 positions of TAGs (PubMed:6643478).  Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity).  In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production (PubMed:1770312).
What are the official names of this protein?
Hormone-sensitive lipase, HSL, Monoacylglycerol lipase LIPE, Retinyl ester hydrolase, REH.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Lipid droplet. Note=Found in the high-density caveolae (By similarity). Translocates to the cytoplasm from the caveolae upon insulin stimulation (By similarity). Phosphorylation by AMPK reduces its translocation towards the lipid droplets.
Protein: CAPSD_BPLSK
Sequence: MNKPDLIEKQNRLAELKENNVSLKSQISGFEVKNAIEDLPKVQELEKTLSENSIEIIKIENELNAQEEKPKGKDKMTNFIESQNAVTEFFDVLKKNSGKSEIKNAWSAKLAENGVTITDTTFQLPRKLVESINTALLNTNPVFKVFHVTNVGALLVSRSFDSANEAQVHKDGQTKTEQAATLTIDTLEPVMVYKLQSLAERVKRLQMSYSELYNLIVAELTQAIVNKIVDLALVEGDGTNGFKSIDKEADVKKIKKITTKAKSAGKTPFADAIEEAVDFVRPTAGRRYLIVKTEDRKALLDELRQATANANVRIKNDDTEIASEVGVDEIIVYTGSKALKPTVLVDQKYHIDMQDLTKVDAFEWKTNSNMILVETLTSGHVETYNAGAVITVS
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=7 symmetry, about 69 nm in diameter, and consisting of 60 capsid proteins hexamers and 11 pentamers.  The capsid encapsulates the genomic DNA.
What are the official names of this protein?
Capsid protein, Gene product 6, gp6.
What is the protein family that this protein belongs to?
Belongs to the Skunalikevirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Main component of the capsid.
Protein: APBC_HAEIN
Sequence: MATYFSDNLTADQQNQVQQIIQQFQHPTLQKDLIVLNTLKKVEKGGDTLRIELQLPFAWNSGAEQLKQAVSDALLKATDCKLIKWAVAYQIATLKRANNQPAVKGVKNIIAVSSGKGGVGKSSVSVNLALALQAQGARVGILDADIYGPSIPHMLGAADQRPTSPDNQHITPIKAHGLSANSIGFLMNEDSATIWRGPMASSALSQLLNETLWDSLDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDIALLDAVKGISMFERVSVPVLGIVENMSMHICSECGHHEAIFGTGGAEKMAEKYNVKVLAQLPLHIRIREDLDAGNPTVVRVPENEISQAFLQLAEKVSTELYWQGSVIPSEILFKEVK
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: RIR2C_ARATH
Sequence: MPSMPEEPLLTPTPDRFCMFPIHYPQIWEMYKKAEASFWTAEEVDLSQDNRDWENSLNDGERHFIKHVLAFFAASDGIVLENLASRFMSDVQVSEARAFYGFQIAIENIHSEMYSLLLDTYIKDNKERDHLFRAIETIPCVAKKAQWAMKWIDGSQTFAERIIAFACVEGIFFSGSFCSIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLLYTLLKTKLSEERVKSIVCDAVEIEREFVCDALPCALVGMNRDLMSQYIEFVADRLLGALGYGKVYGVTNPFDWMELISLQGKTNFFEKRVGDYQKASVMSSVNGNGAFDNHVFSLDEDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  Involved in DNA damage repair and programmed cell death inhibition.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain C, Ribonucleoside-diphosphate reductase TSO2 subunit, Ribonucleotide reductase small subunit C.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic in adult cells, and nuclear in meristematic regions and in all tissues following DNA damage. The nuclear exclusion is dependent on CSN7.
Protein: DER_CROS8
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGSEEGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSRQKPTFLVANKTDGLDPDQAVSDFYSLGLGEIHPIAASHGRGVTSLLEHVLVPWMDDVDPPEEVDEEAEYWAQFEAEQNGELVEEEEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVFDMPGTTRDSIYIPMERDGREFVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEEVKETLDYRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTALLTRIMKMAEEDHQPPMVRGRRVKLKYAHAGGYNPPIVVIHGTQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGANPFANKRNTLTPNQLRKRKRLIKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYT_SALG2
Sequence: MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDATLAIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHDARETFVKRGETYKVAILDENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMGRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQIRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDVIEKLQQEIRSRSLQQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_RHDVA
Sequence: MAFLMSEFIGLGLAGASVLSNALLRRQELQLQRQALENGLVLKADQLGRLGFNPNEVKNVIVGNSFSSNVRLSNMHNDASVVNAYNVYNPASNGIRKKIKSLNNSVKIYNTTGESSV
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the lagovirus VP2 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TRMB_PSYCK
Sequence: MSQHPDINTNVDATSLTDDQKSLDTNATSGNEVAPDGNKHIRIVNTFMKRRTHMNKNAELALTAPEFAHYLVNNSFGDGNLEGIDDLRALFAELPNGSEAPLTLEIGFGLGDSFIEMAAAEPSRNFVGIEVHEPGIGKCAYMAGTQNLSNVRIINGDAIQLLKQLPENHIDRIQLYFPDPWQKKRHHKRRFVSPERMAIVTRSLKQGGWFHTATDWEHYAFWMVEVLDGFVGLSNQAGAGNFTSRPDFRPMTKFERRGLASGHGVWDLIYLKD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NUOB_KLEP7
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKSVYMGKLEHALHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL24_DECAR
Sequence: MMEKIRKGDEIVVITGKDKGKRGTVLRRVDDEHVLVEGVNRAKKHVKPNPVKGVAGGIVDKDMPIHISNVALFNPATKKADRVGFKALDDGRKVRVFKSNGELVNA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: 3SA2_NAJNI
Sequence: LKCHQLIPPFWKTCPEGKNLCYKMYMVATPMIPVKRGCIDVCPKNSALVKYMCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 2, Toxin V(II)2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: CIGA_DICDI
Sequence: MNKFYSLPLIIILIISCGAFFIHGEEAYFEYRIHNEKFIFKLSDDIKIQHARRVLSGDEISLTNVVGKIINKPIEYNINWDFHLDPDSVTFFESETEFCNQKFQYVNGYIDKLCESDNCYFCPWDGSLVRELYFGDIKQDLLLRNNENQQVKQVYEGDIKQDLIRRKNKIHPEKQMHEEDIKQQVFFRIKNIHEKPVYEGDIKQDLLRRKNKNNPEKQVYEGDIKQDLLRRKYYDKSQSTQVYQGDVIQDILRSINRQEKEIYEGDIKQDLLRRNNQNNQEKQVYESDIKQDILRRKYYEKSQSTQVYQGDMTQDILRSLNRQEKGVYEGDIKQDLLRRKYYDKSQSNQVYQGDVIQDILRSINRDKKPVYEGDIKQDLLLRNNQNPQEKSIYEGDIKQDILRRKNLDKSQSIQFYPGDIIQDILRVLNREEKEVYDGDIKQDLLSRKNLAKYQSTEVYPGDVIQDVLRVLNHDEKEVYEVDIKQDLLRRNNKNPQEKPVYEGDIKQDILRRNNLDKSQPKQVYPGDTIQDILRIINRDEKVYEGDIKQDLSGRKNHQEKTVYEGDIKQDLLRRKNLDKPDSKQVYPGDVIQDILRVINRDEKEVYEGDIKQDLLHRNNKNRQEKPVYEGDIKQDLLRRNNKNHQEEQVYQGDIIQDILRVLNHEEKEVYEGDIKQNLLRRKNHDHPEKEIYEGDIKQDLLRRNNKNHQEKLVYEGDIKQDLLRRNNKNHKEEQVYQGDIIQDILRVLNHGEKEVNEDEIEKDLMQRKNHHQEEEASEDLEEEIGKLWNKQSQAFVEQHPNQHNNQKTIHLSRQ
What are the official names of this protein?
Cyclic AMP-inducible protein BP74.
Protein: DAPB_XANC5
Sequence: MTTSAVKVLIHGASGRMGKALLRLAAEDQTLQVVGAVVGRSPSQRVVDGVPFFAASELGGAPAFDVAIDFSLPQGFAPILALCAQRGKPLVSGTTGLDEAQRAALRDAAQQIALVWASNFSLGVAVLTELVERAAGTLPGWDCDILEAHHVHKQDAPSGTALTLGEAATGSGAQPRYVSLRAGDIVGEHTVQFTGLGERVELVHRATNRDIFARGALHAAKLLIGKPAGSYRVRDLVL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALS5_CANAL
Sequence: MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
What is the function of this protein?
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Plays an important role in the pathogenesis of C. albicans infections.  Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
What are the official names of this protein?
Agglutinin-like protein 5, Adhesin 5.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.