PharMolix/UniProtQA huggingface dataset:
Protein: MLH1_YEAST
Sequence: MSLRIKALDASVVNKIAAGEIIISPVNALKEMMENSIDANATMIDILVKEGGIKVLQITDNGSGINKADLPILCERFTTSKLQKFEDLSQIQTYGFRGEALASISHVARVTVTTKVKEDRCAWRVSYAEGKMLESPKPVAGKDGTTILVEDLFFNIPSRLRALRSHNDEYSKILDVVGRYAIHSKDIGFSCKKFGDSNYSLSVKPSYTVQDRIRTVFNKSVASNLITFHISKVEDLNLESVDGKVCNLNFISKKSISPIFFINNRLVTCDLLRRALNSVYSNYLPKGNRPFIYLGIVIDPAAVDVNVHPTKREVRFLSQDEIIEKIANQLHAELSAIDTSRTFKASSISTNKPESLIPFNDTIESDRNRKSLRQAQVVENSYTTANSQLRKAKRQENKLVRIDASQAKITSFLSSSQQFNFEGSSTKRQLSEPKVTNVSHSQEAEKLTLNESEQPRDANTINDNDLKDQPKKKQKLGDYKVPSIADDEKNALPISKDGYIRVPKERVNVNLTSIKKLREKVDDSIHRELTDIFANLNYVGVVDEERRLAAIQHDLKLFLIDYGSVCYELFYQIGLTDFANFGKINLQSTNVSDDIVLYNLLSEFDELNDDASKEKIISKIWDMSSMLNEYYSIELVNDGLDNDLKSVKLKSLPLLLKGYIPSLVKLPFFIYRLGKEVDWEDEQECLDGILREIALLYIPDMVPKVDTSDASLSEDEKAQFINRKEHISSLLEHVLFPCIKRRFLAPRHILKDVVEIANLPDLYKVFERC
What is the function of this protein?
Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis.  Component of different MutL heterodimers that form a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches.  This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  Plays a major role in maintaining the genetic stability of simple sequence repeats, the repair of heteroduplex sites present in meiotic recombination intermediates, and the promotion of meiotic crossing-over.
What are the official names of this protein?
DNA mismatch repair protein MLH1, MutL protein homolog 1, Post meiotic segregation protein 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSY_SULAC
Sequence: MICFDRLKKAFSNFLDKISGEENKKEPETRQTDQLESKKEETIQQQQNVQQPQAENKIEQKQEKISVQTGQENKQENKRSFFDFLKYKTIKEDDLNDVIEELRFQLLDSDVSYEVTEKILEDLKNNLIGKKVSRREEVEEIVINTLKKSITEILTKNQKTDLIEKIRSSGKKPFVIIFFGVNGVGKTTTIAKVVNMLKKNNLSTIIAASDTFRAAAQEQLAYHASKLEVQLIRGKYGADPASVAFDAISFAKSRNIDVVLIDTAGRMHIDSDLVEELKRVLRIAKPDFRILILDSLAGSDALEQARHFENNVGYDAVILTKVDADAKGGIALSLAYELKKPVVYMGVGQNYDDLIPFSPDWFVERIFSS
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor, Docking protein, P41.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: MIAB_CAMC5
Sequence: MSKKLFIQTLGCAMNVRDSEHIIAELSQKEDYTLTQNLEEADLILINTCSVREKPVHKLFSEVGAFEKAKKNGAKIGVCGCTASHLGDEIFKRAPYVDFVLGARNVSKISTAVKTPKFISTDINHDESEYAFGEFRGSPYKSHINISIGCDKKCTYCIVPHTRGDEISIPANLILREVEKAATNGAKEIFLLGQNVNNYGKRFSGAHEKIDFSDLLVRISEVAGVERIRFTSPHPLHMDDKFLEIFSQNPKICKSMHMPLQSGNTKVLREMKRGYTKEWFLDRAAKLREMCPDVSISTDIIVAFPGESDAEFEDTMDVLERVKFEQIFSFKYSPRPMTKAAEFTNQIDEATASARLTRLQSRHNEILDEIVAAQEGKILDVYFEELRANGGVAGRSFNNFLVQVNGSEELLGRTLKVKITDTKRMVLYGELAN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFB20_MOUSE
Sequence: MKLLQVLLVLLFVALADGAQPKRCFSNVEGYCRKKCRLVEISEMGCLHGKYCCVNELENKKHKKHSVVEETVKLQDKSKVQDYMILPTVTYYTISI
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 20, BD-20, mBD-20, Defensin, beta 20.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TJB25_HUMAN
Sequence: QETQYFGPGTRLLVL
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta joining 2-5.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RR4_NAROD
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRSGSDLKNPLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLRYVHIARKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKQRSKALIQNSIASAPREELPNHLTIDSFQYKGLVNQIIDSKWIGLKINELLVVEY
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAA_XANAC
Sequence: MAVDQRPLAIAVMGPTASGKTALALEAAERWNGEIVSVDSALVYRGLEIGAAKPDAAMRAAVPHHLLDLRDPWQVYSAAEFAADARQAIAQIVARGRLPILAGGTGLYFRALLEGLSQLPEADQAVRASIAAEAQQIGWAGLHAQLARVDPVAAARIHATDPQRIQRALEVYRISGRPISAWQALPPGPRLPVRVLKVVLAPRERAVLHARIAHRLDAMLAQDFLTEVRRLRALPQLQAVAAPLDLPAVRAVGYRQAWQYLDGAGSLAEFRDKAIQATRQLAKRQLTWLRGELDARWFDPERDRHQLEDAIVGFLADRPAVRQASGV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MNME_MESHJ
Sequence: MLSDTICAIASGQINQAISIIRISGPNAFKIMEKIFLGKVGRSMEITFGWIHDDNQKIDQVLVLWFAGNKNFVGEDTVEINAHGGVLNTNLILELILKTKLARLANPGEFSLRAFLNGKIDLVKAQAINDLIHAEVKVQHQAALNQFLGKSSNFIKNLIEKIEEIIGIIEVNIDYPEYDDVEILTSDVLLPRINQLLADFDQLIKIANNSRLIYQGIKTCLVGAPNSGKSSLLNILINENKAIISEIPGTTRDVVEGNFVLDGLLFKLFDTAGIRKTTEKIEQIGIEKSYESIKKADLILHIIDASEKNRQNLDLKAKTRPDQIYLKIYNKSDLLENQEEFKDEILISAKYQKIENLLEKIKSIFAFLGKNKEFVANSFQISQIELGKLAILDAKTSLESGFGPEIAIVDLRIAWKELKTIFGRVDDENLLDSIFSKFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMDA1_DROER
Sequence: MAVAEFVFCWPLFELAIVLLVAPIHAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLKLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNSTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGDAADVLRIRRPYELGKPGQSPKVMSANQPGMPMPMLGKTRPQQSVLPPRYSPGYTSDVSHLVV
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Mediated by glycine.  This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning.  It mediates neuronal functions in glutamate neurotransmission.  Is involved in the cell surface targeting of NMDA receptors.  Plays a role in associative learning and in long-term memory consolidation (By similarity).
What are the official names of this protein?
Glutamate [NMDA] receptor subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density.
Protein: SP6_HUMAN
Sequence: MLTAVCGSLGSQHTEAPHASPPRLDLQPLQTYQGHTSPEAGDYPSPLQPGELQSLPLGPEVDFSQGYELPGASSRVTCEDLESDSPLAPGPFSKLLQPDMSHHYESWFRPTHPGAEDGSWWDLHPGTSWMDLPHTQGALTSPGHPGALQAGLGGYVGDHQLCAPPPHPHAHHLLPAAGGQHLLGPPDGAKALEVAAPESQGLDSSLDGAARPKGSRRSVPRSSGQTVCRCPNCLEAERLGAPCGPDGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTGTKKFPCAVCSRVFMRSDHLAKHMKTHEGAKEEAAGAASGEGKAGGAVEPPGGKGKREAEGSVAPSN
What is the function of this protein?
Promotes cell proliferation (By similarity).  Plays a role in tooth germ growth (By similarity).  Plays a role in the control of enamel mineralization.  Binds the AMBN promoter (PubMed:32167558).
What are the official names of this protein?
Transcription factor Sp6, Krueppel-like factor 14.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR7_ECOSM
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYK_SYNS9
Sequence: MSELRDTRLEKANTLEQLGQGPYALTFDPSHRMAELQADHADLPNGEERELSVAVAGRVMTRRVMGKLAFFTLADETGTIQLFLEKAGLEAQQEGWFKQITSLVDAGDWLGVSGTLRRTDRGELSVKVRDWRMLSKSLQPLPDKWHGLADVEKRYRQRYLDLIVSPQSRETFRRRALLVSGIRRWLDERQFLEIETPVLQSEAGGADARPFITHHNTLDLPLYLRIATELHLKRLVVGGFERVYELGRIFRNEGMSTRHNPEFTSVEVYQAYSDYIGMMELTEAMIAEVCQQVCGGTRIHYQGTDIDLTPPWRRATMHELVEEATGLNFEAFTTRAQAAEAMEAAGLEVPGAADSVGRLLNEAFEQRVEASLIQPTFVTDYPIEISPLARKHRSKPGLVERFELFIVGRETANAFSELIDPVDQRQRLEAQQARKAAGDLEAQGLDEDFVHALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFPLMRPESRPDEAPSVG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO2A1_BOVIN
Sequence: MIRLGAPQTLVLLTLLVAAVLRCHGQDVQKAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDMKDCLSPETPFGECCPICSADLPTASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQMGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKSGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAAGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGAGPAGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGSQGLQGARGLPGTPGTDGPKGAAGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGTAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGDPGLQGPAGPPGEKGEPGDDGPSGPDGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPIGKQGDRGEAGAQGPMGPAGPAGARGMPGPQGPRGDKGETGEAGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGQREKGPDPLQYMRADEAAGNLRQHDAEVDATLKSLNNQIESLRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMETGETCVYPNPASVPKKNWWSSKSKDKKHIWFGETINGGFHFSYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTVLKDGCTKHTGKWGKTMIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL
What is the function of this protein?
Type II collagen is specific for cartilaginous tissues.  It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
What are the official names of this protein?
Collagen alpha-1(II) chain, Alpha-1 type II collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PYRB_THEPD
Sequence: MVSGLGSRGNPFYGRDVLSILDFSRSDLEYLFAEADRVRRDPSAFSGELRGYVLATAFFEPSTRTRLSFQAAMLRLGGSCIDLGELEKSSIAKGENFADTVRMLDAYADVIVVRHRLEGAARFAAEVAEKPVINAGDGKRHHPTQAMLDLYSVKTLKGSVDGLVYGVLGDLKYGRAAASFILGLSLFKPRKVYLISPGLLKAREDVKEALRERGVGFEEVESPSEVIGELDVLYVTRIQRERFPDPSEYEKVRGSYVVDSKLLRNAKEGLIVLHPLPRVDEISFDVDGTPHAKYFEQARLGIPLRMALLKLVLKG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GDL48_ARATH
Sequence: MATHYLSPSILCIILTTLVSIAGAKIPAIIVFGDSSVDSGNNNFISTMARANFEPYGRDFPGGRATGRFCNGRLSSDFTSEAYGLKPTVPAYLDPSYNISDFATGVCFASAGTGYDNSTADVLGVIPLWKEVEYFKEYQSNLSAYLGHRRAAKIIRESLYIVSIGTNDFLENYYTLPDRRSQFSISQYQDFLVEIAEVFLKDIYRLGARKMSFTGISPMGCLPLERVTNLDDPFSCARSYNDLAVDFNGRLRRLVTKLNRELTGIKIYFANPYDIMWDIVTKPNLYGLEISSSACCGTGLFEMGFLCGQDNPLTCSDANKFVFWDAFHPTERTNQIVSDHFFKHLKNLFH
What are the official names of this protein?
GDSL esterase/lipase At2g42990, Extracellular lipase At2g42990.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_CLOAB
Sequence: MYNILDNYEDVDDIKNMSSDELKEFASEIRKFLIDKISKTGGHLASNLGVVELTLSLHKVFNLKKDKIIWDVGHQAYVHKILTGRKDKFDSLKQFNGLSGFPKRNESIYDAFETGHSSTSISAASGIARARDLSKDNYDVIAVIGDGALTGGMALEALNDIGYKKTNVIIILNDNQMSIAKNVGSISKYLNKIRLDPKYNKLKKDVKTKLQRTNIGSEVANSIERIKGGIKQMVVSGMFFEDIGIKYLGPIDGHNIEELTSVISKAKEIKGPVILHVKTQKGKGYSYAEENPNKFHSIGKFNSKTGEALSKPKDTYSKAFGKAMVQMAENNDKIVAITAAMTDGTGLCEFSKKFPQRFFDVGISEQHAVTMAAGLAATGYKPVFAVYSTFLQRAYDQVLHDVCIQKLPVVFAIDRAGIVGEDGETHQGVFDISYLSSIPNMTIMAPKCVEELNYIMNWAVKQNYPIAVRYPKGGNDISDVLAPLKEFRHGKWEILKDGKDVAIVAVGKMVQRAMVVRDELLKYGIDCAIINATFIKPIDKDTLNRFARDNYKFVVIEDNVLHGGIGSLILEHLNDMKFKNDVLNLGFKDEFITHGNIEILYKLYDLDIEGICKRIISFK
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y4869_RHOBA
Sequence: MNPILVLLCVIALGLLVGRVSFRGISLGTSAILFVALLAGHYGWTIPTGFGTLGLALFVYCVGISAGPTFFRGLASHGRAMAITGSVIVLTGVAVTWTSARLLGLPAELAGGLMAGAMTSTPALGAITQSSSDPAAVAVGFGVAYPIGIIAVVLFVQIAIKLFAKPGDSDGTDSASETSGQSSAEIAESNSIGRRVVRIANPVVSGKRPSDIVAFADSPCQMSRVQREGRWRPTPPDYQFEIGDDVMLVGGASEIRRVSETLGELQDTAEPVVDADRERRYVVVTSPEIYGRTLKELRLRSKYGVTIVRVQRHDVEFVPSARTRIEFGDGLVAVGEPDALAKIANAVGHRPRTVNETDLLSLVAGIVLGIFVGNLSLQIGEFSMSLGIAGGPLMVGLILGHFRRLGPIRGSYPPAAMLLMTEGGLALFLADAGLNAGANVVEVLMERGAMLCVAAAAIAIIPLLVGFAGSRYFGGRTLWQSLGATCGGMTSTPGLAVLTGATDSSQPATSYVAAYPVALVLITVAAPWLVELIG
What are the official names of this protein?
Uncharacterized transporter RB4869.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_GEOUR
Sequence: MDELKNIIRDIPDFPKKGIIFKDITTLLADAASYQRMVDLLSHRYIGKKIDKVVGVEARGFIIGAALAYKLGAGIVLVRKPGKLPSETFKKSYELEYGTDTLEIHTDAIEKGERVLIADDLLATGGTMAAVVDMVSSMGAELVECCFMAELEFLNGKNKLPADKVFSLLKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SHESM
Sequence: MSKRTFQPSNLKRKRSHGFRARMATVGGRKVLARRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SYH_DEIDV
Sequence: MAIKRPKGTQDHLPDGSPKLSLDTRAAAFTFVRETARRVLERAGAQFTDTPLFEEAELVQRGVGGSTDIVRKEMFTVYYFGDHGGFILRPEGTAGLVRSYLQNGLKQLPAPLKLWTHGPMFRAENVQKGRLRQFHQVDYEVLGSADALVDAEAIALMTEVVRALGVQKVKVKLGSIGDPEDREAYNTYLRELFTPHLEALSDDSKDRLNRNPMRILDSKSESDQTLIAQLGVRPMLDFLGEGARTHFEQVQAYLNAWDVSYEVDPSIVRGLDYYRRTAWELHHEGVGAKSALGGGGRYDGLAQELGSKEVVPGIGWAFGIERLLLAMDAEGVALPETSGPLLYVAAMDDENVTYAATVALTTRRTARAEFAYRAMKPAAAFRDAERRGARFIALIGSDEVAQDTLSIKNLQTGQQSKVQTRDLQAFLAGQADQHSPAIPHDPTPQEKA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_YERPS
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGSIENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHDALANTIVVVATASESAALQYLAPYSGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDVELAKVGSFEAALLAFADREHAELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MCP_PBCV1
Sequence: MAGGLSQLVAYGAQDVYLTGNPQITFFKTVYRRYTNFAIESIQQTINGSVGFGNKVSTQISRNGDLITDIVVEFVLTKGGNGGTTYYPAEELLQDVELEIGGQRIDKHYNDWFRTYDALFRMNDDRYNYRRMTDWVNNELVGAQKRFYVPLIFFFNQTPGLALPLIALQYHEVKLYFTLASQVQGVNYNGSSAIAGAAQPTMSVWVDYIFLDTQERTRFAQLPHEYLIEQLQFTGSETATPSATTQASQNIRLNFNHPTKYLAWNFNNPTNYGQYTALANIPGACSGAGTAAATVTTPDYGNTGTYNEQLAVLDSAKIQLNGQDRFATRKGSYFNKVQPYQSIGGVTPAGVYLYSFALKPAGRQPSGTCNFSRIDNATLSLTYKTCSIDATSPAAVLGNTETVTANTATLLTALNIYAKNYNVLRIMSGMGGLAYAN
What are the official names of this protein?
Major capsid protein, MCP, VP54.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RS21_BORBZ
Sequence: MVTVTVDKNENLEKALKRFKRMIEKEAIIREWKRREYYEKPSTIRVKKEKAFKRKQAKKVRKLKQKTNR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DCA13_XENLA
Sequence: MKVKVLCRNPDDYVRETKRDLQRVPRNYDPALHPFEVSREYTRALNATKLERVFAKPFIASLDGHRDGVNCIAKHPKSLSTVLSGACDGEVKIWNLTKRECSRTIQAHDGFVRGLCVRFCGTSFFTVGDDKTVKQWAMESPGYGEKVEPMRTILGKTVFTGIDHHVKDAVFATCGQQVDIWDEQRSAPMRSYAWGVDSISSVRFNPVETHILSSCGTDRSIVLYDKRKPTPLKKIILEMRTNALCWNPMEAFIFTAANENFNLYTYDMRYMDSPVKVHMDHVSAVLDVDYSPTGKELVSASFDKSIRIFPVQSGHSREVYHTKRMQHVTCVRWSADNKYVLCGSDEMNIRIWKANASEKLGVLSPRERAAQNYNQKLKEKFQHHPQIKRIARHRHLPRSIYSQIKEQQIMREARRKKDVNRRKHSKPGSVPIPSEKKKHVLAVVE
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 13, WD repeat and SOF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF13/WDSOF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component.
Protein: RL16_RICRS
Sequence: MLAPKKQKFRKAHKGRVASTAKAGTTLAFGSFGLKSIDGWRVTARQIEAGRKAATRCMKRQGRLWIRIFPDVPVSQKPAEVRMGKGKGSPEFFAVRVSPGRIMFEIEGVEENVALRALELASAKLPVRTRIVRRYE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AMY1_DROAN
Sequence: MFLAKSIVCLALLAVANAQFNTNYASGRSGMVHLFEWKWDDIAAECENFLGPYGYAGVQVSPVNENAVKDSRPWWERYQPISYKLVTRSGNEEQFASMVRRCNNVGVRIYVDVVFNHMAANGGTYGTGGSTASPSSKSYPGVPFSSLDFNPTCAISNYNDANQVRNCELVGLRDLNQGNSYVQEKIVEFLNHLIDLGVAGFRVDAAKHMWPADLGVIYGSLKNLNTDHGFESGAKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKAFRGKNQLQYLVNWGVSWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDGQNIASPSFNSDNSCSGGWVCEHRWKQIYNMVGFRNAVGSDAIQNWWDNGSNQIAFSRGSKGFVAFNNDNYDLNSSVQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRANISIGSSEDDGVLAIHVNAKL
What are the official names of this protein?
Alpha-amylase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.