PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_NEIMA
Sequence: MLSNIIPLSIGAALGATARWLLNLAVPASLSPATGNLFANWTGAFLIGIFAETVNHPQWKLLLITGFLGSLTTLSGFSLETVTLLQSNRPASALANIFLHTAGSLLLTWLGLKIGTAVK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_DESAP
Sequence: MARYTDARCRLCRREGTKLYLKGDRCYSPRCAVDRRPAPPGQHTPSRRKVTEFGIQLREKQKVRRIYGVLESQFRNYFHKAERQPGVTGENLLRLLELRLDNVIYRLGLGASRAEARQLVRHGHFKVNGRKVDIPSYQVRVGDVIAVRERSKGLTRIQELLDRASENNPPAWLEYDGERAVARVVALPTRENIDIPVREQLVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MNMA_ROSDO
Sequence: MPLDPSPTLNSLGFAKPPAETRVVVAMSGGVDSSVVAAMLAEEGYDVVGVTLQLYDHGAALAKKGACCAGLDIHDARRVSEKMGFPHYVLDYENIFKDAVIDEFAESYLGGATPVPCIRCNERVKFKDLLETAKDLDADCMATGHYIQRKSGPYGAELHSAADANRDQSYFLFSTTPEQLAFLRFPLGHLPSKEDTRALAEKYGLSVANKPDSQDICFVPDGDYASVIRKLRPEAAAPGDIVDTDGRVLARHDGVVNYTIGQRRGLGIGGLATPLYVIKLDAEARQVVVGPKSMLSTRTVPVREINWLGDEPFQSRDAWHLAVKVRSTRPPTDAIIRPISDTEATVELTSPEEGISPGQACVFYDTDSSRIYGGGWIHKG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAEA_BOTFB
Sequence: MVVAMAMANNGSLSPAPPAAFQEPPPDYTENGRLYHGLHKGKYMFPCDEDEKDRMDIFHKFFEVAMGGVLHSRNTTFTNNYDGPRILDLGTGTGIWAIDMADKYGSDMGTGEVLGLDLARIQPPTIPENLQFLQRDIESPWWGLEVESWDMVHIRMLSGSINSWPALYQKVRRYLKPQVGRFEQVEIDFTPRSDFGDIPADSALATWARNLFEATRRNFRPLAYNTEIRAMLQKEEFLDIQEEVIRIPLNPWPDDPQEKDVARWYNLALTQGLEAMTLGPMHRIYGWTKDDVTRLITEVRRDICNRKIRAYNNLHVWTARAPVKPPS
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:25625818).  Controls the expression of the oxalic acid gene cluster (PubMed:25625818).  Controls also the expression of proteases and carbohydrate-active enzymes (PubMed:25625818).  Regulates sclerotia formation and plays a role in virulence (PubMed:25625818).
What are the official names of this protein?
Secondary metabolism regulator LAE1, Methyltransferase LAE1, Velvet complex subunit LAE1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_PSEPF
Sequence: MAMTVHCDIVSAEGEIFSGLVEMVIAHGALGDLGIALGHAPLITNLKPGPIRLIKQGGEAEVFYISGGFLEVQPNMVKVLADTVQRAADLDEAQAQAALKAAEAALHEKSADFDYGAASARLAEAAAQLRTVQQIRKKFGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SUCC_SALTI
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RT23_BOVIN
Sequence: MAGSRLETVGSIFTRTRDLIRAGVLKEKPLWFDVYNAFPPLREPVFRRPRLRYGKAKSPTQDIYYHEDQIRAKFYAAYGSGPKAFDLFNPNFKSTCQRFVEKYIELQKLGETDEEKLFVEAGKALLAEGVILRRVEKARTQQEGSQVSRKSESMGVESQTALEENPPLKEVPQAQHLESPGEESKGLSPP
What are the official names of this protein?
28S ribosomal protein S23, mitochondrial, MRP-S23, S23mt.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IOLG_SERP5
Sequence: MTLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHDLVKAADVQAVLVTSWGPSHEEFVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRLVQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTVGEAYTTDMAITDTLIHEIDVLRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCEVVGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPSAWDGYAAAVTADACVAAQLSGEIVPVTLPPRPAFYNK
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: Y5975_DICDI
Sequence: MLQSLKNVFFSDTTTTTTPTTPTTPTTPTTTPTTTTTPTTTPTTTTTSTTPISNLSIKRDIGNINDYKNANYFNYYRILENKYNYLRYNTGLKNISNNETFKLIDFTIDSEMNNTCITSNWNQKYSNNSSTPVEGVYKIPLAPYSVVSGFTVEYQDKVFIGKIKSKEKAQNQYSDSIASGGQAFLAEKTQDGQFSFRIGNLPPNENVTIHLTIISEVCPHLSSLQNCFHRFLFPNYSFNFQFNLNIKLTLPIKTIELLYYPNKDIKFKENSNNKEATLTFSSNNGIDDDIVCIVEPENDIERPQSIIEHSKLNNTYAVSVNFTPSFSHLTSDDVNQKSEFIFLIDCSGSMSGEPIKKAKRALEIIIRSLNENCKFNIYCFGSRFTKAFDNSKMYNDETLKEISGYVEKIDADLGGTELLPPIRDILSTESDFEYPRQLFILTDGEVSERDSLINYVATESNNTRIFTYGIGNSVDTELVIGLSKACKGYYEMIKDNSNFEEQVMKLVSIAFEPTLSNIKVDWGTELQIEQGPTKIRPLYSGETLIVYALLKDNKIPQSTVQVSLIGDGPTGSKLEFPITLDFSKTIDYENNSVHTLAAFNIIKDLEEVERKGNHSNNRDRIEELGKNYGLISKYTSYIVTAASEQVTEETMKTLNIIQIPTTTTTSHTNFETEEDSDDLFSSENRNQTLANISNDMEKIKDIFDDISRLISEQSCMLNEIGDANIEASTLGINSIPQKSNIFSKITSFFSSPSEVSTSKSNFDSDIGSEERRNNNNNNNNNNININNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSDNSDSLLKLIRLQKANGSWSSPFSEFKIDLSKKPSNIDNDDIWITLIVINKILNDYPTQQSQYDLVIQKASKWVKQQLTRLNIPNQYGSLLATSKLYI
What are the official names of this protein?
von Willebrand factor A domain-containing protein DDB_G0285975.
Protein: MHU_BOMMX
Sequence: ILGPVLSLVGNALGGLLKNE
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Maximin-Hu, Maximin-8.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_SINFN
Sequence: MNQPLKPNSFRAGPDEDGRFGIFGGRFVAETLMPLILDLQDEWNKAKNDPVFKAELEKLGAHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGHGTLKDAMNEALRDWVTNVDSTYYLIGTAAGPHPYPEMVRDFQAVIGQEAKEQLLAAEGRLPDLVVAAVGGGSNAIGIFHPFLDDDGVRIVGVEAGGKGLDGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHAWLNDIGRVEYVPIMDHEALEAFQTLTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDIFTVGKILGMGQ
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: EFG_SULDN
Sequence: MARSHKLEDVRNIGIAAHIDAGKTTTTERILFYTGREHKIGEVHDGAATMDWMEQEQERGITITSAATTCEWAGKQINIIDTPGHVDFTIEVERSMRVLDGAVSVFCAVGGVQPQSETVWRQRNRYGVPSIVFVNKMDRTGANFYAVEEQIRTRLKGNPVPIQIPIGEEDNFLGVIDLVKMKAIVWDVDAAMGSNYHVEEIPANLLQKAQEYREKMIESISEVDGNEHLAEKYLEGEELSEDEIIAGIKAATIGMHIVPMTAGTSFKNKGVQTLLDAVVAYLPAPTECAPIKGTMMDDEDEEVIVPSTDSGEFASLAFKIMTDPFVGTLTFIRVYRGSLEAGSFVHNSTKDKKERIGRIVKMHAVKREDIKEIYAGEIGAVVGLKYTTTGDTLCSEADKVILERMTFPEPVISVAVEPKTKADQEKMGLALAKLAAEDPSFKVHTDEETGQTIISGMGELHLEILVDRMKREFKVEAEVGAPQVSYRETIRDTVNQEYKYAKQSGGRGAFGHVYLTIKPGDAGTGFVFHNEIKGGVIPKEYIPAVEKGCAETMSNGVLAGYPMEDIDITLYDGSYHEVDSNEMAFKLAASMGFKEGCRKARPAILEPLMKVEVEVPEDYMGDVIGDLNRRRGQVTNMGDRSGNKIVDAFVPLAEMFGYSTDLRSATQGRATYSMEFDHYEEVPKNVSEEIIKKRNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YT001_HUMAN
Sequence: MESPKCLYSRITVNTAFGTKFSHISFIILFKVFLFPRITISKKTKLVTLSNYLNK
What are the official names of this protein?
Putative uncharacterized protein PRO0628.
Protein: RL3_STRM5
Sequence: MTKKYSLGFVGRKAGMSRVFTEDGRSIPVTLIEATPNRIAQIKTVETDGYSAVQVTVGARRAALVNKPEAGHFAKAKVEAGRGLWEFRVEDAQLGDFAVGGEVKADIFEVGQIVDVQGVTKGKGFQGTIKRHNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVQQSTQNLEVVKVDVERGLIAVRGAVPGAAGGDVIVRPASKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: BACD2_PONAB
Sequence: MSGDTCLCPASGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSCSQASPSEDEETFELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure.  The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.  Its interaction with RHOB may regulate apoptosis.  May enhance the PCNA-dependent DNA polymerase delta activity (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2, BTB/POZ domain-containing protein TNFAIP1.
What is the protein family that this protein belongs to?
Belongs to the BACURD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.
Protein: HSF8_SOLPE
Sequence: MEPNSSGSGKAAVGDGGGGGAPMLQPAPAPAPMPSANAPPPFLVKTYDMVDDPSTDKIVSWSPTNNSFVVWDPPEFAKDLLPKYFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEGFLRGQKHLLKSISRRKPAHGHAQQQQQPHGHAQQQMQPPGHSASVGACVEVGKFGLEEEVERLKRDKNVLMQELVRLRQQQQSTDNQLQGMVQRLQGMELRQQQMMSFLAKAVNSPGFLAQFVQQQNESNKRIAEGSKKRRIKQDIESQDPSVTPADGQIVKYQPGINEAAKAMLRELSKLDSSPRLENFSNSPESFLIGDGSPQSNASSGRVSGVTLQEVPPTSGKPLLNTASAIAGQSLLPATSEMQSSHLGTCSEIINNQLSNIIPLVGGEDLHPGSLSASDMIMPELSQLQGILPENNTDVIGCDSFMDTIAVEGKMGLDIGSLSPGADIDWQSGLLDEIQEFPSVGDPFWEKFLQSPSSPDAAMDDDISNTSETKPQINGWDKTQNMEHLTEQMGATNIKQQKHMI
What is the function of this protein?
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.
What are the official names of this protein?
Heat shock factor protein HSF8, Heat shock transcription factor 8, HSTF 8, Heat stress transcription factor.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_PSYA2
Sequence: MNIRPLHDRIVVRRIEEETKTAGGILLPGSAQEKPSQGEVLATGNGQIRDNGETRALDVKTGDKVLFGQYAGQTVKVDGEELLIMKESDVLGVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTHP_LATSK
Sequence: MEKRDFHVVADTGIHARPATLLVQTASKFNSDVNLEYKGKSVNLKSIMGVMSLGVGQGADVTISAEGADEADAINAIEETMKKEGLSE
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER35_ARATH
Sequence: MARFDIVLLIGLCLIISVFPDTTTAQLSRGFYSKTCPNVEQIVRNAVQKKIKKTFVAVPATLRLFFHDCFVNGCDASVMIQSTPKNKAEKDHPDNISLAGDGFDVVIQAKKALDSNPSCRNKVSCADILTLATRDVVVAAGGPSYEVELGRFDGLVSTASSVEGNLPGPSDNVDKLNALFTKNKLTQEDMIALSAAHTLGFAHCGKVFKRIHKFNGINSVDPTLNKAYAIELQKACPKNVDPRIAINMDPVTPKTFDNTYFKNLQQGKGLFTSDQVLFTDGRSRPTVNAWASNSTAFNRAFVIAMTKLGRVGVKNSSNGNIRRDCGAFN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 35, Atperox P35, ATP21a.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHI_PROM3
Sequence: MFGFLKKVADYTRDAADAANYLIQGLAVTFDHLRRRPITVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPVVDWVMNKETKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELAAYDRHSLNYDNVALGRLPTSVTTDPSVQPLRELAYLPKGVMDPHDVPANQPRAGQLPAEVLKSLSLQQDSLQGDEGESLQDAPDQDQPKG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RL33_YERP3
Sequence: MAKGVREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LIPA_BRUA2
Sequence: MVTVLNTVNQSGRLRHPEKAHRPDNEVLKKPDWIRVKAPVSRGYGETREIVRSNKLVTVCEEAGCPNIGECWEKKHATFMIMGEICTRACAFCNISTGIPNALDPNEPENIAKAVKQMGLTHVVITSVDRDDLADGGAHHFAEVIKAVREAAPATTIEILTPDFLRKEGALEIVVKARPDVFNHNLETVPSKYLKVRPGARYFHSIRLLQRVKELDPTIFTKSGIMVGLGEERNEILQLMDDLRSADVDFMTIGQYLQPTRKHHPVIRFVKPDEFKSFETIGKTKGFLLVASSPLTRSSHHAGEDFAKLKAAREALYASRAS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_CAMC1
Sequence: MSEEVKEQNLPEVEPVQEAASDSVNLDALGDISKVEKLEKELGEITDKYYRANAEFENIKKRYEKEKADVASYANEKFARDLLPVIDALEIAANFDPEDDEFAKKIKEGILITINQFKKCFEKHGVSEIATDADFDPNVHNAVLRVDSEEKQSGQIVQALQKGYMINGRVLRPAMVSVAN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAM4_XENLA
Sequence: MLKRLDKIRFRGQKRDDFLDLVESPNASDTECGDEIPMKIPPTSLKDTEELKDPAGSGTIIMASGVAEYNRTESDRLNEVKGHLEIALLEKHFLQEELRKLREETNIDTLKQELEKERQRRTELEQKITDIAKTRTDESATQQLSKGPSQTNGADKQRSKTMCYRVQKWFYDKFGEYIEDFRFQPEECTVETEEPLSARRLTENMRRLKRGAKPVTNFVKNLSALSDWHSVYTSAIAFIIYMNAVWHGWAIPMFLFLAILRLSLNYLIARGWRIQWSIVPQVSETLELPKEDLTVSEKFQLVLDVAQKAQNLFGKMADILEKIKNLFMWVQPEMTQKLYIGLWAAFVASCFFHYKTIGLCMGLYAGIKFFLIDFIFKRCPRLRAKYDTPYIIWTSLPTDPQLKERTNATSSRRIQTVYSRGNLASSAPQGVSRDEETGRFHSTKKSSFHEIFSLLETERPLPACETGWRCCLINRDRKMPTDYIRNGILYVTENFLCFESSRSGSSKRNKVIKLTDITDIQKYKVLSVLPGSGMGIAVSTPSTQKPLVFGAMVHRDEAFETIFSQYVKITSAVTNSDT
What is the function of this protein?
Plays a role as a mediator of e2f1-induced apoptosis in the absence of p53/TP53.
What are the official names of this protein?
GRAM domain-containing protein 4.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GRAE_MOUSE
Sequence: MPPVLILLTLLLPLGAGAEEIIGGHVVKPHSRPYMAFVKSVDIEGNRRYCGGFLVQDDFVLTAAHCRNRTMTVTLGAHNIKAKEETQQIIPVAKAIPHPDYNATAFFSDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGDVCSVAGWGSRSINDTKASARLREAQLVIQEDEECKKRFRHYTETTEICAGDLKKIKTPFKGDSGGPLVCDNKAYGLLAYAKNRTISSGVFTKIVHFLPWISRNMKLL
What is the function of this protein?
This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
What are the official names of this protein?
Granzyme E, CTL serine protease 2, Cytotoxic cell protease 3, CCP3, Cytotoxic serine protease 2, D12, MCSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Cytolytic granule.
Protein: MURD_SALPA
Sequence: MADYQDKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRVTPPGLDKLPQEVERHVGGLNDEWLLAADLIVASPGIALAHPSLSAAASAGVEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDADRELYVLELSSFQLETTSSLQAAAATVLNVTEDHMDRYPFGLQQYRAAKLRVYEKAKVCVVNADDALTMPVRGADERCVSFGVNMGDYHLNRQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAVGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLTGDRIRLYCFGRDGAQLAALRPEIAQQTETMEEAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGDVFTRLAKELG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPTR_PANTR
Sequence: DLGAVIYLLLWGRQLFALYSSNDVTDISDDRFPKPPEIANGYVEHLFRYQRKNYYRLRTEGDGVYTLNDKKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSRHNLTTGATLINEQWLLTTAKNLFLSHSENATAKDSAPTLTLYVGKKQLVEIEKVVLHPNYHQVDIGLIKLKQKVLVNERVMPICLPSKNYAEVGRVGYVSGWGQSNNFKLTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYAAGILSFDKSCAVAEYGVYVKVTSIHVWVQKTIAEN
What is the function of this protein?
Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL).  Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.
What are the official names of this protein?
Haptoglobin-related protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma and associated with subtypes of high density lipoproteins (HDL).
Protein: SAP4_ORYSJ
Sequence: MEHKEAGCQQPEGPILCINNCGFFGSAATMNMCSKCHKEMIMKEEQAKLAASSIDSIVNGCDGGKEHIVAASGSTAVAVAQVEAKTLVVQPTDVAGTSEEVAVVPKVKEGPNRCATCRKRVGLTGFNCRCGNMYCALHRYSDKHECQFDYRTAARDAIAKANPVVKAEKLDKI
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 4, OsSAP4.
Protein: RBL_SYNS9
Sequence: MSKKYDAGVKEYRDTYWTPDYVPLDTDLLACFKCTGQEGVPKEEVAAAVAAESSTGTWSTVWSELLTDLDFYKGRCYRIEDVPGDKEAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKCCAGPPNGIAVERDRMNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDFTKDDENINSQPFQRWQNRFEFVAEAIKLAEQETGERKGHYLNVTANTPEEMYERAEFAKELNQPIIMHDFITGGFTANTGLSKWCRANGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDQLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALVAIFGDDSVLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAGKHSPELAIALETWKEIKFEFDTVDKLDVQ
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.