PharMolix/UniProtQA huggingface dataset:
Protein: EIF3I_YEAS7
Sequence: MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERDSATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKSYFDFKYDVEKAAEAKEHMQEAN
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y066_SACS2
Sequence: MRRLPAVAGSFYESDPKKLKMQIEWSFRHNIGPRDIPKQSYEKKKRDNLFFIVPHAGYIYSGPVAAHSYYYLASEGKPDVVIILGPNHTGLGSYVSAWPKGEWETPLGSVKVDEEVLMQLVMESEVIDLEEKSHLYEHSIEVQLPFLQYFFDDNFKIVPIVIMMQTPEIAEFLADAIYKVIQKYSDKDIVVLASSDMNHYDPHEITMKKDEEAIEKIQQLDYRGLYEVVEGKDVTLCGYGPIMVSLILAKKLGKKAYILKHATSGDTSGPKDSVVGYLAARFGS
What are the official names of this protein?
MEMO1 family protein SSO0066.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: RS12_SHEB8
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTIRGALDCAGVTSRRQSRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: EX7S_CALS4
Sequence: MEKEFNFEEDLKRLEEIVDTLEKGNLMLEESFNLFKEGVEISKRLEKMLKEVEGKITMLISEDEEIEFKEEENNV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRGB_BACC4
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MFD_STAAS
Sequence: MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKYAQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERIRTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGYKRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTKIDSIRDFDVETQRSKDNVEEVDITTASDYIITEEVISHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDHQILRRLVAFMYETPSTIIEYFQKDAIIAVDEFNRIKETEESLTVESDSFISNIIESGNGFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMRSEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLSEGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGVGRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGSEWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQAKSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKDLGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIAVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTEYIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHSGITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQWLDSLKFLVKCIEESMRISDEA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1574_METJA
Sequence: MEDVFKGIEKEIIKIYKIPERKGRFSNFKFKNKEINELIDALGFKLYLHQVKALKYLYNKKDVVVTTSTASGKSEIFRLAIFDNFLSNPDDRYLLIYPTRALINNQYEKFSMENELFYKITNKRVKAEILTGDVGLEKRREILKDKPNVLFTTPDMLHYQILKNHNNYLWLLKNLKLLVVDELHVYRGVFGTNMVYVFKRLLKLLKRLNNNLQILCLSATLKNPKEFVKLLFNRDFEVVDKSYNPSSRKYLAILEPKNLDNKQLLRRLIENLVDNNIKTLVFFDTRKETEKLMRFLLNSKVFYKLSTYKGTLPKYVREEIEEKFKNGEILALLTTNALELGIDIGDLDAVINYGIPPDGIFSLIQRFGRAGRRDKEALNIIVLRKDGLDYYYKEHLNELYERIRKGIIEYMPVNIKNRFVTKKHLHYLISELKIVDFDELNDFEKEIVKELEREGKIKIYKNPITNKTEIRNVKQPIYSSIRTASDESYYLILDKPWIKSKLLNKTQSEILSFINWLKIKGYVIEEVDKDEYYRSLITGMPYFSRGKLFIAKDKIGIRKFHFIFADELDMFWDVEALQKKEEEIDILDIYDKKSYKDIDIYYGRLRVRKIYEGFIVRGVDVDKYYQELLALKDNGILDAEIDLFKDFFGLNFISVKFNKKIIRDFETDGIWLCYFQIILGMLTK
What are the official names of this protein?
Uncharacterized ATP-dependent helicase MJ1574.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: MLTF_SHEB9
Sequence: MTRFLFALILGFLLTACQQVTVDETEFVPKKLTELRVGTLYGPQIYMTSGQGDSGFDYDMAVLFAEYLDVPLKMVPYTNRTELYEALKKNEIDLIAAGMTETPARREQFRLGPPLYRVNQVLVYREGMPAPKDISDLKGKITVIADSSFVETLTQLQKHYPTLVWDQITDKDSEELLAMIANKEIDYTIADSSSVQINRRYLPDLRSGPVLEEKLDVVWLLPPTRSDELMSQLLAFWHQEKLAGTLDHLNEKYFGHVKRFDYVDTRAFIRAIETVLPRYRQLFETHAGNLDWRKLAATSYQESHWNPHARSATGVRGMMMLTQPTAKEIGITNRLDAEESIRGGAAYLNDMINRLPESIPESQRMWFALASYNIGYAHVEDARKLAESMELNPNAWRDLKKVLPLLQKRKYYQKTRYGYARGSEAVHYVDSIRRYYDTLVWVDNQSKQQNPEEEPSDLASEEPAIPAGTLSPEQPK
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: PUR8_MACFA
Sequence: MAAVGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLDNIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTDKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQADAYFSPIHSQLDRLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL
What is the function of this protein?
Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ADSL, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: RL17_RICBR
Sequence: MRHKIKGRKLNVTSSHRKAMLANMAVSLVTHEQIKTTLPKAKELRPYIEVLVTKAKDNNLAARRNILSKIKDKKAIEKLIDVLGVRYKDRPGGYTRIVKAGFRYGDLAPIAYIEFVDRDINAKGNIPQDNSKEDIKSNKGTK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: IQG1_CANAL
Sequence: MAIGNIAARYLSSLEETDTTATTTTTTTSNVLQPSNRLNSPTKFNRKSLDNNSQDLDALARALNITPSKPETPTSISKGSATSLLRTKFESPSATVSSFKSTSSSNGVSPTKKNHFVEITSDETPSWANKNYKDILNKSPTKFNTQSNVHTPLKQLNQPIGTPSSSSLSPAKNASKSSPGYEYLCRIEAIKQWLESVLQEQITQSASQLISYIRNGIHLAKLANVVLPTSKPVFLNDSKLQFKHTENINRFFQLLDFFNMPDLFRFELTDLYDAKNVPKVWFCLHALSYILHKQDPSYPAMNNLVGKVDFSADDIRTANRALVNSPLPNFSSADTGEGKSDTSNNNSSTTSATAAFMDKVTSPVKKTPSPLKRPQQLQKKQLELVEDNKPELTQDSSGLSKISRDDPFTDRVDLAPPSTSNAKLELHTPPSKSLEFKIKSPIIDLSHRDSDYYTPELESHLPNIIKFQSLARGAVFRYLMFVDRILLKSYQDEFTNLFAIIRGNKARRKTVHKHRDELRLYSFEIIELQSIIRKNFVINKKPNFTSITNDVETVELQSLIRGKLTRDWKKYVTNGLEKFTPQIIDFQSLVRMKSIYSKSNKVISYKDEILPSLIELQSIARSQLYHRFSRSNAIDETEIIKIQSIIRRNAVIEDLYTKLSKVRSNKRRLIELQSIARGGVARTKLCNSVLVTLIYEDGILNQLFAKIRGDNYRKKFNSQKSELLKYEKSSIIPVQTLFRGVLSRYTKEVTLSDIFDQIDSVITLQSVARGKLMRGSIYEFSDYYQKHIKQVVKAQAILQRVFAQNAYKQLITSKNPPLKVIRRFAPLLSNNDRDFQDEMTLSDLKDLIIEKCKANEEYENQIEQLDMKLGLLDKNKISIEEFLKPTKGKTFKPIVENVKNLERLNKSLKKKIELWQTLFYFIQTNPIYLTKLFNSIPYTKNQTKSGQDLFQSVIQLFPVRDSSITYHSREEYFLVKLMIQLMQNDTANSNNLGDITKLHLTNWIDFFTNFNNHTFQRQHLKALLGKFVIRIVDNEQVDFESDPIRIYNQIIDHEMKVYGRSEKSRDISPQAAIQLPEVSNKFVGNLMSLRETCSDLLSMLQKNASGNKALLQIPDHVKLICRQGYLCAQRKFPDKSDQQHLAVAGVIFVKHYLGSILQVPENYGILTGNNDTQKAKSKDNLRYLYRVMLQLFSMKPFNDNFLKPLNEYIMASTDTVKSIISQAIINVGEIETVYELHDYDDLVTHQRPKLTISVNSLIQLEKSILQNVDIITTGNDDQLYKTCVEVEKLLISPQDMLTLTDLSSVTLNLNPTTQEESIVDSKTKTLFTQAKRCLLYIIRVQEEDDSDDLLELLISGIKPSHEQRFKEIVQYEKAEQDISLNNSKSVTANTVNKKKSTRPYSGTSLGDLSNLTYHELKKMCLEIILKLESMGELTRKNSFQTLLNQIAMDIKTKDSQRQCRWQQLQVSQKTIKKLSEKENYLKTQLHNYKKHVESVLLELQSKSKSNDKNWKRRLFNIMVIPVFSKQYFYHRELRKHNRLPKFGSYKYSAKKLIDQKVLIDFSTANNVATASKLDFMFSCHQVGKFTIEVASGTVNIPGATNTITLDELLALQYENKTKFELFDGMATFDSNNFMGLIFRKFYDLKKE
What is the function of this protein?
Required for the assembly and the contraction of the actomyosin ring at the bud neck during cytokinesis.
What are the official names of this protein?
Ras GTPase-activating-like protein IQG1, Cytokinesis protein 1, IQGAP-related protein 1.
What are the subcellular locations of this protein?
Bud neck. Note=Forms a ring at the bud neck in a MLC1-dependent manner, which contracts at the end of cytokinesis.
Protein: PURT_POLSJ
Sequence: MTTFGTPLSPHATKVMLLGSGELGKEVLIALQRLGVETIATDRYDNAPGQQVAHHARTITMSDPAQLKSLIEKERPHLVVPEIEAIATAMLEELEAAGTVRVIPTARAARLTMDREGIRRLAAETLGLPTSPYVFCDSLQELQAAIDTNIGYPCIVKPVMSSSGKGQSKIAGPADVKTAWDYAMAGGRVSHGRVIVEGFIDFDYEITQLTVRALGADGQVETHFCEPIGHIQVSGDYVESWQPHPMREAALQKSRAIAKAVTDDLGGQGLFGVELFVKGDEVWFSEVSPRPHDTGMVTMCTQWQNEFELHARAILGLPVNTALKSSGASAVIYGGVDAKGIVFDGVADALRVPNTDIRLFGKPESFVKRRMGVALAFDADVEVARANAKLAASRVKPRVAKG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: GLGC_LACPL
Sequence: MQDEMLGIILAGGQGTRLGKLTKDTAKPAVPFGGRYRIIDFTLSNCANSGVNTVGVITQYQPLELNAHIGSGASWGFDSLNGGVTVLQPYSSSEGEKFFQGTAHAIYQNIEYIDQQDPKYLLVLSGDHIYKMDYDAMLKYHQEKKASLTVGVIHVTNEEAKRFGMMNTDATDRIIEFEEKPEHPKSDKASMGIYIFNWPTLRDYLVKSYATDKSLEDFGKNVIPSYLANNESVYAYAFKGYWRDVGTIKSLWQANMEFLSPHNRLNIGDRYWRIYSKAEVLPPMFLTETSQVNNAMVVDSCYVAGEIDHSILSQRVSVGMGSRVVDSMIMPGATIGKNVVIDHALIGEDAVIGDDAQIIGTTDKIAVVGYHETMGVEQP
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PYRH_SYNPW
Sequence: MAYARALLKLSGEALMGDQGYGIDPAIVQAIAKDVAGVVASGTQLAIVVGGGNIFRGLKGSAAGMDRATADYVGMLATVMNAITLQDGLERAGIPTRVQTAIEMQEVAEPYIRRRAIRHLEKGRVVVFGAGCGNPFFTTDTTAALRAAEISADVVFKATKVDGVYDKDPHKYADAVRYDTLTFQQVLSGELAVMDSTAIALCKDNNIPIVVFNLFEAGNIGRAVAGEPIGSRISN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HJA1_METJA
Sequence: MAELPVAPFERILKKAGAERVSRAAAEYLAEAVEEIALEIAKEAVELAKHAKRKTVKVEDIKLALKK
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.  Increases the resistance of DNA to thermal denaturation (in vitro).
What are the official names of this protein?
Probable archaeal histone 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: YTOI_BACSU
Sequence: MATKHEQILTYIDSLPVGEKISVRRIAKEMKVSEGTAYRAIKEAENKGFVSTIERVGTIRIEQKKKENIEKLTYAEVVNVIDGQVLGGRAGLHKTLNKFVIGAMELDAMMRYTAAGNLLIVGNRINAHRQALEAGAAVLVTGGFNTDDSIVQLADELELPILSTSYDTFTVAAMINRAIYDQLIKKEIVLVEDILTPADRTVYLSPKDKLEKWYEKNFETGHGRFPVVDDQMKIHGILTSKDIAGHDRNASIEKVMTKNPVTVIGKTSVASAAQMMVWEGIEVLPVTDGHQKLIGMISRQDVLKALQMIQKQPQVGEKLDDIVSRGFKDEGDDKEDQTVYEYEVTPQMTNQLGTISYGVFTTILTQAANRFLRSKKRGELVIESITIFFLKPVQMESVIEVKPRILEAGRKFGKMEVEVHSQGHIVSKAMLMVQLMERS
What are the official names of this protein?
Uncharacterized protein YtoI.
Protein: OBG_MYCSS
Sequence: MPRFVDRVVIHARAGNGGNGCASVHREKFKPLGGPDGGNGGRGGSIVLVVDPQVHTLLDFHFHPHVVAPSGKQGAGSNRDGAAGADLEVRVPDGTVVLDEEGRVLADLVGAGTRFEAAAGGRGGLGNAALASRSRRAPGFALLGEKGQVRELTLELKTVADVGLIGFPSAGKSSLVSTISAAKPKIADYPFTTLVPNLGVVSAGDHTFTVADVPGLIPGASEGRGLGLEFLRHIERCAVLVHVVDCATMEPGRDPISDIEALEAELAAYRPTLQGDSTLGDLAERPRAVVLNKIDVPDARELADFVRDEVAERFGWPVFEVSTVAREGLRPFIFALWDMVRTYREAQPPVVPRRPIIRPIAVDETGFSVHPDGQGGFVVRGTRPERWINQTDFDNDEAVGYLGDRLARLGVEEELLRLGARPGCAVTIGDMTFDWEPQTPAGVDVQMSGRGTDTRLEQTDRVSAAERKIARRERRQSTDEPGGEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPPA_CHLAA
Sequence: MQDLNAVQSLAVWAVLVISLLGIGYAFFIRSQILAQDTGTPKMREVWGFIKTGANAYLSQQFRTISILIVILTFVLAASVFIIPPTTEAVERFGSKEAATIWVAIGRAVAFLMGSLFSYAVGFVGMNVAVEGNVRVAAAARKGYNPALQVAYKSGSVTGMLTVGLGLLGGTLIFMVFGIAAPDALLGFGFGGSLIALFMRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNAAVIADLVGDNVGDCAGMAADVFESFEVTLVSALILGLVLGDAVVGTIGDGAYDLRFIIFPLVLRAIGVVASVIGNLFVTTDERKRNAMAAMNRGFYIAAGLAIAASAAATPVFMVNEATGEVDWRPFFATLSGVVLAIVLDKLTEYFTSTHFSPVKETSKASQTGSATNILSGLALGMESSVWAILVISASIFTSVLIYAGEPAATQFTAILYGVSLTGIGMLLLTGNTISMDSFGPISDNANGIGEMAGLDKNARNVMDDLDAVGNTTKAVTKGIAIGSAVIAAVALYGSYFTDVNKVLQQMINEGRQGIELLASINVAAPPVFIGLLIGGAVPFLFSALTIRAVSRAAAQIVNEVRRQFRIPGLMEGKVQPDYARAVQISTTAAQKELISLGLIAVMVPIIVGFTLGVEALGGFLAGIILTGQLMAVFQANAGGAWDNAKKYIEEGNFGGKHSEPHKAAVVGDTVGDPLKDTAGPALNPMIKVINLVALIIAPIVVTIEPGSPGVIIAMIICGAALVWAIWQSKRESEALKEIAQAPASAD
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force.
What are the official names of this protein?
K(+)-insensitive pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIA8A_PANTR
Sequence: MSPCGRARRQTSRGAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQGVLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYSLFPQATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLERCEDTSLQPTS
What is the function of this protein?
Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid (By similarity).  Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (By similarity).  Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (By similarity).
What are the official names of this protein?
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase 8A, SIAT8-A, Sialyltransferase St8Sia I, ST8SiaI.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: UXAC_BRUME
Sequence: MALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPDHYITRMLYSQGHSLESLGIASRDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMETVFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNIEAISTTDAATDPLIYHDEVIASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRGATSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVMQIHPGSFRNHNPTVFERFGLDKGADIPRQTGFVDQLKPLLDAFGNDPRLTVILFTLDETALSRELAPLAGHYPALKLGPAWWFFDSPEGILRYRKLTTETAGFYNTVGFNDDTRAYLSIPARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: SAMC_DANRE
Sequence: MDRREFTASLVAGGCAGMCVDLTLFPLDTIKTRLQSQQGFYKAGGFRGIYAGVPSAAIGSFPNAAAFFVTYESTKSVFSGYTTTNLAPITHMLAASLGEIVACLIRVPTEVVKQRTQANPSISTYRVLLNSLQEEGFRGLYRGYGSTVLREIPFSLVQFPLWEYLKAVWWRRQGGRLDSWQAAVCGALAGGVAAFVTTPLDVAKTWIMLAKAGTSTASGNIPMVLCEVWRSRGIPGLFAGSIPRVMFISMGGFIFLGAYEKVRRTLL
What is the function of this protein?
Mitochondrial S-adenosyl-L-methionine/S-adenosyl-L-homocysteine antiporter.  Mediates the exchange of cytosolic S-adenosyl-L-methionine, the predominant methyl-group donor for macromolecule methylation processes, for mitochondrial S-adenosylhomocysteine(SAH), a by-product of methylation reactions.
What are the official names of this protein?
Mitochondrial S-adenosylmethionine carrier protein, SAM carrier, Solute carrier family 25 member 26.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL6_ESCF3
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RTL1_ORYSJ
Sequence: MQQQQHPAPGAEFVADRDAARAEVERALGGYSFRDGGALLLEDALTHSVHPRDEAGGRARHQRLEFLGDAALGLAFATIFYRDDPGLDQGDLTVLRSANVSTQKLARVAVRRRLYPLLRRYNCAPQDHEVSRFTKSVEGPYSGDPIEGPRVLADIVEAIVGAVYLDSKLDLEVLQKVAKLLCEPIITKKALLEDPESMLNELGGEHREDLEIKILAWRKVANVVDDGREQAITTSGLGNGSEDEVGKLRTIRIEEA
What is the function of this protein?
Cleaves double-stranded RNA (dsRNA).
What are the official names of this protein?
Ribonuclease 3-like protein 1, Ribonuclease III-like protein 1, RNase III-like protein 1.
Protein: FETP_METCA
Sequence: MARRIICAKLGIEADGLDAPPFPGPQGQRIFEHVSKEAWQDWLKLQTMLINEHRLTPFEASARKFLEQEREKFLFGGGTSTPQGYVPPRS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RS2_FRAP2
Sequence: MSLMKEMLSAGVHFGHKKAFWNPQMKEYIFGINHGVHIINLEKTVPLFQDAVNFVGKTVANGGKVLFVGTKRQAQDIIEAEAKRCGMPFVSHRWLGGMLTNYKTVRQSIKRLAQLEKMKEDGTFESLTKKEMLQNIRTIEKLEKVLGGIKEMGGLPDAIVVIDSNKEHIAIQEAQKLGIKVVSIVDTNSNPEGIDYIIPGNDDAVKSISFYMKKFADAVIDAQGLDRAVEAKAEETTEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CUTA_YERPN
Sequence: MSDSDAMTDPNAVSYSNAIVVLCTAPDEASAQNLAAQVLGEKLAACVTLLPGATSLYYWEGKLEQEYEVQLLFKSNTDHQQALLTYIKQHHPYQTPELLVLPVRDGDKDYLSWLNASLL
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCAL2_RHEAM
Sequence: DEQEGCASGWVPFDGRCFGFFPQELSWRRAEGFCQRLGARTHLASIHSEEEHQAIMSMLASSQPYSESEEEVADEEVWIGLHRPMGRRHWEWSDGTKMDYSSWYREGFPRRRACAALEDSTDFASWDTELCSDRKPFICEYHV
What are the official names of this protein?
Rheacalcin-2, RCA-2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Eggshell matrix.