PharMolix/UniProtQA huggingface dataset:
Protein: CBID_BURTA
Sequence: MRDETPEQPAPLRFGYTTGSCATATSLAAARLLLTGHASDMVDIVLPKGQHVAMRLAFCRATDGGAEAGTIKDAGDDPDVTHGALVFARVRLVHEPGVRFRAGPGVGTVTRAGLTIGVGEPAINPVPRRMMTEHLAALAAEHGYAGGFEVAIGVENGEALARKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGVTHIAACTGNASEDAVRARYGLPDIALIEMGDFAGAVLKYLRRASVERLTLCGGFGKLSKLAAGHLDLHSRHSSIDLPRLAQWAGEAGASAVLQHEIRAANTSQQALSLALAHHVPLGDVVCAHARRVARDIVPDEVDVETLAIDREGRIVGVAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PYRE_ROSDO
Sequence: MIPSAYPDAKEMARLTARMLLEIHAVHFNAKDPFTLSSGLPSPTYIDCRKLISFPRIRATLMDFLTVTVMRDVGFEAFDNIAGGETAGIPFAALVAERMALPMTYVRKKPKGYGRNARIEGAMGEGERVLLVEDLTTDGGSKLSFVDAIRETGATCGHTAVIFYYDIFPETTKTLGDHGVALHSLCTWWDVLAEAKQQGVFDEATLSEVEKFLHNPRKWQEANKK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: GLYA_THEFY
Sequence: MTAQSTSLTQSLAQLDPEVAAAVDAELARQRDTLEMIASENFAPRAVLEAQGTVLTNKYAEGYPGRRYYGGCEHVDVIEQLAIDRAKALFGAEHANVQPHSGAQANTAVYFALLQPGDTILGLDLAHGGHLTHGMRINYSGKILNAVAYHVRESDGLIDYDEVEALAKEHQPKLIIAGWSAYPRQLDFARFREIADQTGALLMVDMAHFAGLVAAGLHPNPVPYADVVTTTTHKTLGGPRGGLILAKEELGKKINSAVFPGMQGGPLQHVIAAKAVALKVAASEEFAERQRRTLSGAKILAERLTQPDAAEAGIRVLTGGTDVHLVLVDLVNSELNGKEAEDRLHEIGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDADFAEVADIIAEALKPGFDAATLRSRVQALAAKHPLYPGL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOC7_HUMAN
Sequence: MIPPQEASARRREIEDKLKQEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKEALESEFRSLMTRHSKVVSPVLILDLISGDDDLEAQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFHKSSSSSGVPYSPAIPNKRKDTPTKKPVKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGLLPCTPRGGLPGPWINAACVCAADISPGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYQLLADIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIVRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQIIKERFKGFNDGLEELCKIQKAWAIPDTEQRDRIRQAQKTIVKETYGAFLQKFGSVPFTKNPEKYIKYGVEQVGDMIDRLFDTSA
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.  In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion (By similarity).  It is required for neuron survival and plays an essential role in cortical development (By similarity).
What are the official names of this protein?
Exocyst complex component 7, Exocyst complex component Exo70.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
Protein: UPPP_GEOMG
Sequence: MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFRRDIAELVVNALSGLTGGAHSSATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAAFLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLALLPGVSRSGITITAALFLGFSRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLLKLVQRYSLYPFVWYRLLAGAGVLLFIFNQ
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCP_YERPS
Sequence: MRRVLITGFEPFGGERINPSWEVVKQMNDLMMGGVRIVARQLPCAFGEALTALNTAIDDVQPVLVLAIGQAGGRADITIERVAINVDDARIPDNLGNQPVDQPIIQEGPAAYFTRLPIKAMVQGIREAGIPASVSQTAGTYVCNHVMYGLLHRLNQFNNEVKGGFIHIPYLPEQAVDHPGAPSMSAQSVLVALELAISIALQIEHDLHITGGAVH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYW3_MOUSE
Sequence: MDRSAEFGRWKAQSLSKADLSRKGSVDEDAVEVVELLNSREEFFTTSSCAGRILLLDGSTEGSGVQKQHCCWLLVTHKPCARDDVMAALKGATSEAVLKFEPFILHVQCRTLQDAQTLHSVAIDSGFRNSGITVGKRGKTMLAVRGTHGLEVPLTHKGKLMVTEEYIEFLLTIANQKMEENKRRIGRFYNYLQHALKRETISNSHSKIKERNNPLCTHKNRRSQGKAQGPSTTEDNGRELEDGDGLEISAALFLGDD
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3, tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: PNP_CLOBM
Sequence: MIHTLETTVAGRKMKVDFGKTGMLSNAAIFMSYGDTVVMINANASKEPREGIDFFPLSVEYEERLYSVGKIPGGFIKREGKPSDKSILHARSIDRPLRPLFPKGYRNDVQIVNTVLSVEQDNLPEILAINGSSLALCLSSIPFTTPVAAVSVGLVDGEFIINPTVAQRENTILDLTVCATKERVMMVEAGGQEIDEETMYSAIMFGFEECKNIVAFQEEAVAKFGKTKNEPVLYKADEEVEKEVKSFAFDMIKEAMYIMDKDERNAQLDKVKEKISEEFSEKYEDKVADIAEVIYKTQKEIVRNMLLNEDRRPDGRAFDEVRPISCEVGILPRTHGTGLFTRGLTQVMTVATLGALGDVQILDGIAEEESKRYMHHYNFPSYSVGEVRPLRGPGRREIGHGALAERALEPLIPSESEFPYTIRLVSEVLSSNGSTSQASVCGSTLALLDAGVPIKRPAAGIAMGLITSEDLEKEKVITDIQGIEDFFGDMDFKVAGTEKGITSIQFDTKIKGLSNSCVKDALEGAKKARLHILGKIKECIPEPRKELSKYAPRTEIICIDPEKIRDVIGAGGKVINKIIADTNVKIEIKEDGKIFVTSNNEPEGVKKAISIIEGLTKEVVQGEIYLGKVTKTTNFGAFVEILPGKEGLVHISKLDFARVEKVEDVVSVGDEILVKVTDIDNQGRINLSRKDAIAKKEEEKDK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSPO_CERSP
Sequence: MNMDWALFLTFLAACGAPATTGALLKPDEWYDNLNKPWWNPPRWVFPLAWTSLYFLMSLAAMRVAQLEGSGQALAFYAAQLAFNTLWTPVFFGMKRMATALAVVMVMWLFVAATMWAFFQLDTWAGVLFVPYLIWATAATGLNFEAMRLNWNRPEARA
What is the function of this protein?
May play a role in the transmembrane transport of tetrapyrroles and similar compounds, and thereby contribute to the regulation of tetrapyrrole biosynthesis (PubMed:10409680).  Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX (PubMed:23651039).  Binds protoporphyrin IX, hemin, and coproporphyrin III, but does not bind delta-aminolevulinic acid (PubMed:23952237, PubMed:20541505, PubMed:25635101).  Can bind bilirubin, curcumin, gossypol, retinoic acid, cholesterol and the benzodiazepine receptor agonist PK-11195 (in vitro) (PubMed:23952237, PubMed:25635101).  Plays a role in the response to low oxygen levels and in the regulation of the biosynthesis of photosynthetic pigments (PubMed:7673149, PubMed:10409680, PubMed:10681549).
What are the official names of this protein?
Tryptophan-rich sensory protein, TSPO, Translocator protein TspO, TspO regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell inner membrane; Multi-pass membrane protein. Note=Outer membrane proteins generally mediate transport processes by forming beta-barrel structures, and unlike TspO, their transmembrane domains do not contain any helices. Detected in the cell inner membrane when expressed in E.coli (PubMed:20541505). This suggest that TspO is in the inner membrane, even if experiments shown in PubMed:7673149 suggest location in the outer membrane.
Protein: CXP3_PARCG
Sequence: GWPAYPGSNGIRSSVCQKKLGCGSKNLASLGVCKAFCPGRKRFWQKCGKNGSSGKGSRICNPVPAHAVEKAGKGLIKVTDMAVAAIAKYAGKK
What is the function of this protein?
Cytolysin that shows hemolytic activity (on bovine erythrocytes, HC(50)=5. 75 mg/ml).  This hemolytic activity is completely inhibited by small unilamelar vesicles composed of PC/PG, PC/PI and PC/PS in 1:1 molar ratios (with at least 100 mg/ml concentration).
What are the official names of this protein?
Parbolysin P3, Parbolysin 3.
What is the protein family that this protein belongs to?
Belongs to the worm cytolysin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_CORDI
Sequence: MINGTVRIRLDLAYDGTDFHGWARQGDSDLRTVQKIIEDTLTLVLQRPIDLTVAGRTDAGVHATGQVAHFDVDPAALETRSIAGDPARLIRRLARLMPDDVRIHNMSFVPAEFDARFSALRRHYVYRVTTHPRGALPTRARDTAHWPRSVDISAMQAAADALIGMHDFAAFCKYREGASTIRDLQEFTWHDVSTPQEPQLYEAHVTADAFCWSMVRSLVGACLVVGEGKRADGFTEHLLGETKRSSSIPVAAACGLSLVGVDYPSDDQLGARAEQARAYRTHDELPSL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PASM1_LACPN
Sequence: MSKLVKTLTVDEISKIQTNGGKPAWCWYTLAMCGAGYDSGTCDYMYSHCFGVKHSSGGGGSYHC
What is the function of this protein?
Bacteriocin with a narrow antibacterial spectrum.  Antibacterial activity against the Gram-positive bacteria L. plantarun, L. pentosus, L. curvatus, L. lindneri, L. mesenteroides and E. faecilis.  Lacks antibacterial activity against the Gram-positive bacteria L. brevis, L. sakei, L. lactis, P. acidilactici, B. subtilis, B. cereus, L. monocytogenes and S. aureus, and against the Gram-negative bacteria E. coli and S. typhimurium.
What are the official names of this protein?
Bacteriocin plantaricin ASM1.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_AGRFC
Sequence: MRVAIIDYGSGNLRSATKAFERAAREAGIDATIDLTDKPDHVASADRIVLPGVGAYADCSAGLNAMPGMHEALIEAVEKKAHPFLGICVGMQLMSSRGLEKTVSTGLGWIEGDVVEMTPSDPTLKIPQIGWNTLEIRHAHPLFDGIKTGADGLHAYFVHSYHLAAKHSTDVIATTNYGGAMTAFVGRDNMAGAQFHPEKSQTLGLALISNFLRWKP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_HELHP
Sequence: MAKGSTIKIGLKCSECGDINYSTTKNAKTNTEKLELKKFSPRLNKHTIHKEVKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ADCK_DROME
Sequence: MLLRRVLGYGVVGAGLASAGWSLHTNDYDPNSLGIVRLSRSAAAVVDVALTYKRELYYKEWDKETPEYKAEKSRVHKIAAEKLLQLICINKGVYIKVGQHIGALEYLLPKEFVQTMKVLHSDAPQNPIEDLYKVIRQDLHCNPEEIFDSFEREPLGTASLAQVHKARLKTGELVAVKVQHPYVKGNSRVDMKTMELAVNVLARIFPDFKIHWLVEESKKNLPIELDFLNEGRNAEKVAKQFKKYSWLRVPKIYWKYSSSRVLVMEYLEGGHVTDLDYIRRNKIDSFAVANRIGQLYSEMIFRTGFVHSDPHPGNILVRRTPENSLEIVLLDHGLYANLTDKFRYDYSNLWLSILKVDRKAMRQHSEQLGIKGDLYGLFACMVTGRPWETVMQGLTKVKYSKEEKNTLQNNTSLVLPHISDVLEQVDRQMLLILKTNDLIRGIESTLRTQNRMTAFWVMSKCCVQSSYAEQRAKQSDSGSSRILWLRVRERWELFKLNCYYLYLGLINFGFLEALKQVI
What is the function of this protein?
Essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L to regulate the mitochondrial structural proteins Opa1 and Mitofilin (PubMed:31125351).  This function is likely to be kinase-independent (By similarity).  Functions in tracheal development and larval molting probably by acting in sterol modification and/or intracellular lipid trafficking (PubMed:31175694).  The action of this enzyme is not yet clear (Probable).  It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).
What are the official names of this protein?
AarF domain-containing kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAT9_HUMAN
Sequence: MRLNQNTLLLGKKVVLVPYTSEHVPSRYHEWMKSEELQRLTASEPLTLEQEYAMQCSWQEDADKCTFIVLDAEKWQAQPGATEESCMVGDVNLFLTDLEDLTLGEIEVMIAEPSCRGKGLGTEAVLAMLSYGVTTLGLTKFEAKIGQGNEPSIRMFQKLHFEQVATSSVFQEVTLRLTVSESEHQWLLEQTSHVEEKPYRDGSAEPC
What is the function of this protein?
N-acetyltransferase that mediates the acetylation of the N-terminal residues of alpha- and beta-tubulin.
What are the official names of this protein?
Alpha/beta-tubulin-N-acetyltransferase 9, Embryo brain-specific protein.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: RL34_HERAR
Sequence: MKRTYQPSVVRRKRTHGFRVRMATRGGRAVLNARRAKGRKRLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GAGXE_DROME
Sequence: MNTLNETAAADESLDTAFLSSPQCAAPQRFQKIKRKSRASPETERKKPKSTIGKQGENPSATEPRYGGNSNRFGLLAHLTADKQVGNEIGDLYDQPSTSHQAAIAAAKRDAASAGTTSSAKRAQSKPPPIVMEGVDDVYLMMQSIENIVDLEKIEARASMSGVLRLYAADANTFRTIVNWLEIEEYEFHCYQLKEDRPYRVCVKGLHHSTLHHQIKDELEKIGHKVLDIHTPLRRNEPGTSKASPVNMFFLNIAAAANNKEILAVKALCHMRVVIEPLRKRNAIVQCHRCQQIGHTAKYCRKAHICVKCAGEHPAKDCTRPRIELCTCYNCGGQHPANYKGCSKLQAFLQRSRPRSGVAGRTEVSDRPTPRGLAGGKEIPSSRGGISYADVARGSIHHKQPMSLTHQQQKQKQQPYDGSPSRQRSRSRTRASRGTLQRSTDASSSIEAILQTLNENINSLRSIQEKQMELMMMMMKQQQQQSHQQGQIINLLTALQARQAP
What is the function of this protein?
Strongly basic protein that binds directly to retroviral RNA and may be involved in its packaging and in the reverse transcription process.
What are the official names of this protein?
Nucleic-acid-binding protein from transposon X-element.
What are the subcellular locations of this protein?
Virion.
Protein: TI8AB_MOUSE
Sequence: MESAWSSRGTSLGSSDPQLQRFMEAEVQKQRVQLLIHHMTELCWEKCMDKPGPRLDGRAELCLVNCVERFIDTSQFILNRLEQTQKARPLFSERLSD
What is the function of this protein?
Putative mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Putative mitochondrial import inner membrane translocase subunit Tim8 A-B.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: NHRF1_RAT
Sequence: MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLKKLGVPIREELLRAQEKSEHTEPPAAADTKKAGDQNEAEKSHLERCELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKAGGDEAKLLVVDKETDEFFKKCRVTPSQEHLDGPLPEPFSNGEIQKENSREALVEPASESPRPALARSASSDTSEELNAQDSPKRHDSTEPSSTSSSSDPILDFNISLAVAKERAHQKRSSKRAPQMDWSKKNELFSNL
What is the function of this protein?
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.  Necessary for recycling of internalized ADRB2.  Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3.  Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3.  Involved in sperm capacitation.  May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.  May enhance Wnt signaling.  May participate in HTR4 targeting to microvilli (By similarity).  Involved in the regulation of phosphate reabsorption in the renal proximal tubules (By similarity).
What are the official names of this protein?
Na(+)/H(+) exchange regulatory cofactor NHE-RF1, NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus. Endomembrane system; Peripheral membrane protein. Note=Colocalizes with actin in microvilli-rich apical regions of the syncytiotrophoblast. Present in lipid rafts of T- cells. Translocates from the cytoplasm to the apical cell membrane in a PODXL-dependent manner. Colocalizes with CFTR at the midpiece of sperm tail (By similarity).
Protein: TILS_VIBCM
Sequence: MDDLYLHFVQQLARYPFRKILLALSGGVDSQVLLALLARGRDEFGWDVTAVHVHHGLSPNADQWAQHCQRCCREVGMACQIEYVQLDVASGESIEKLAREARYRVLAPHVNAQTLLLLGQHADDQLETFLLALKRGSGPKGLAAMAAYAPFAEGHLLRPLLTVSRQHIEAYAKQHKLTWVIDESNADIRYERNFLRHQVTPVLTERWPSIRQAVQRSAELCAEQEALLQEFLAEALKKAITAEGGLSIAVLAEGSEGMRRQLIRAWFAHHRLPMPSRQHTERIWCEVALASEDANPKLKLNHIEVRRFQHCLYLVPPEKDLSGWRSALVPEQRLPLPQGLGHLQLTSKAGGNIKLPDDPSQLWVSFEPQGLEACPVGRVGSRKLKKLFQEYGVPSWRRRQTPILMYQNRVVCVADLFVDRDWSGQDCELVWFKSHDSVPK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PITX1_HUMAN
Sequence: MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQYNS
What is the function of this protein?
Sequence-specific transcription factor that binds gene promoters and activates their transcription.  May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
What are the official names of this protein?
Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOAC_CHLSY
Sequence: MSEAHNELTHLDAAGHARMVDVGDKAVTAREAVARGRVVMQPETLALIMDGKLPKGDVLAVARVAGIMAAKRTAELIPLCHLLNLSHASVQFTPDPASNALEIEATVRCQGQTGVEMEALTAVSIAALTIYDMCKAVDKTMQIDQIRLIAKRGGRSGDWQRPR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: XERD_AGRFC
Sequence: MSGQPMAGRDGARLESFLEMMSAERGAAANTLSSYEHDLADLREFLGRRGQSLTEAQTPDLSAYLTHLAAQGFAATSQARRLSSMRQFYRFLYSEGLRGDDPTGIIDAPRKGLALPKTMSVADVNRLLGLAAQEAATEGPGQLARIRMHLLLELLYATGMRVSELVSLPVKVLRQEGRFLMIRGKGNKDRMVLLSRAAIEAMEKYEAGRKALSQEKSKAAASQKKTDTAESPWLFPSNSKEGHLPRQVFARDLKDIAIRAGLTASAVSPHVLRHAFASHLLQNGADLRAVQELLGHSDISTTQIYTHVLEERLQELVQTHHPLAKQGKNLD
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPSD1_ECOLX
Sequence: MKLFKSILLIAACHAAQASAAIDINADPNLTGAAPLTGILNGQQSDTQNMSGFDNTPPPSPPVVMSRMFGAQLFNGTSADSGATVGFNPDYILNPGDSIQVRLWGAFTFDGALQVDPKGNIFLPNVGPVKVAGVSNSQLNALVTSKVKEVYQSNVNVYASLLQAQPVKVYVTGFVRNPGLYGGVTSDSLLNYLIKAGGVDPERGSYVDIVVKRGNRVRSNVNLYDFLLNGKLGLSQFADGDTIIVGPRQHTFSVQGDVFNSYDFEFRESSIPVTEALSWARPKPGATHITIMRKQGLQKRSEYYPISSAPGRMLQNGDTLIVSTDRYAGTIQVRVEGAHSGEHAMVLPYGSTMRAVLEKVRPNSMSQMNAVQLYRPSVAQRQKEMLNLSLQKLEEASLSAQSSTKEEASLRMQEAQLISRFVAKARTVVPKGEVILNESNIDSVLLEDGDVINIPEKTSLVMVHGEVLFPNAVSWQKGMTTEDYIEKCGGLTQKSGNARIIVIRQNGAAVNAEDVDSLKPGDEIMVLPKYESKNIEVTRGISTILYQLAVGAKVILSL
What is the function of this protein?
Involved in the translocation of the polysialic acid capsule across the outer membrane to the cell surface.  May function as the periplasmic binding element of the PSA transport system, in which it transiently interacts with the membrane component of the transporter, binds polysaccharide and transports the polymer to a component in the outer membrane.
What are the official names of this protein?
Polysialic acid transport protein KpsD.
What is the protein family that this protein belongs to?
To E.coli K5 KpsD.
What are the subcellular locations of this protein?
Periplasm.