PharMolix/UniProtQA huggingface dataset:
Protein: V_MEASA
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAIEEAMAAWSEISDNPGQERATCREEKAGSSGLSKPCLSAIGSTEGGAPRIRGQGPGESDDDAETLGIPPRNLQASSTGLQCYYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDNESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSGTPIKKGHRREISLIWNGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation.  Moderately affects the type II interferon signaling (By similarity).
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: CXB3_HUMAN
Sequence: MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction beta-3 protein, Connexin-31, Cx31.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: COFI_USTMA
Sequence: MSSGVKVSQECLDKFQELKLGKKIKYIIYSLNDKNTEIVVQNTSTSTSYDDFLAELPPTECRYAIYDFEYEKGDAGKRNKICFFSWSPDDAKIKPKMVFASSKDALRKALVGISTEIQGTDFSEVSYDTVLDKVSRSTF
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  Binding to F-actin is regulated by tropomyosin.  It is the major component of intranuclear and cytoplasmic actin rods.  Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends.  In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments.  Involved in the maintenance of the contractile ring once formed.  In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton (By similarity).
What are the official names of this protein?
Cofilin, Actin-depolymerizing factor 1.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Note=Throughout the cytoplasm (but not on the cytoplasmic cables) and major component of the cortical actin cytoskeleton.
Protein: GSH1_LEPIN
Sequence: MKTKELTQSKIEEVSLEILLRHAVKAKHGLEKESMRVNPDGTLSGTTHPIHLGSSLTNHYIKTDFAEPQLEYATHPRPKVEANIRELQDLHIFTIRKLENELIWPFSMPPVLPEEENEIPLGQYGTSHSGRWKTIYRHGLGLRYGRRMQTISGVHYNFSFSKVFLRQFLGKEISNFTKEEISSLYLHVIRNFLRRVHFLTYLTGSSPVFDFTFLPNPGSLKFEKHKNFTLYSTYATSLRMSEIGYTSKVQDTLGIHYNSLEEYVDRMCYAVHTPYPKYVSFSENKDAQLNPNYLQIENEFYSPIRPKQVPKGDERPLDALLQRGIEYIEIRSLDIDPYSPVGVCRSNLAFTQLILLDSLLKVSPSISEEENFSLKENLNSVIWEGRNPELKINVNGSKRNFQEAGAEYSESLRHYAKILDLHTGRRTYQEAIDFQIKKWKNPDKTPSGKLLSEILKRNIEFREKGIELAQENKRMFSYLEYSPGTLMKMEKETIRSFQEKEELEKQEIQTQYPTVKLCNH
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: UBIE_CHRVO
Sequence: MDKTTHFGYKTVAESEKAGKVAEVFHSVASKYDVMNDLMSGGLHRVWKHFTLTTSGVRAGDKVLDIAGGTGDLSRGWAKRVGKTGEVWLTDINSSMLTVGRDRLLDEGVILPVSLADAEKLPFPDNYFDAVSVAFGLRNMTHKDAALKEMCRVLKPGGKLFVLEFSKVWKPLSPFYDFYSFKALPIMGKLVANDADSYQYLAESIRMHPDQETLKQMMLDAGFGKVDYHNLTGGVVALHKGVKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EFP_BRUME
Sequence: MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFIASGERVIVDTNELTYISRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH3L1_MOUSE
Sequence: MHTSTEARMGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIKDALA
What is the function of this protein?
Carbohydrate-binding lectin with a preference for chitin.  Has no chitinase activity.  May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.  Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation.  Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs.  Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells.  Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance.  Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
What are the official names of this protein?
Chitinase-3-like protein 1, BRP39 protein, Breast regression protein 39, Cartilage glycoprotein 39, CGP-39, GP-39.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Endoplasmic reticulum. Note=Detected in bronchoalveolar lavage (BAL) fluids. Localizes mainly to endoplasmic reticulum when overexpressed in cells, with some protein also detected throughout the cytoplasm.
Protein: MINJ_BACSU
Sequence: MSVQWGIELLKSAGLFFLHPLFWFFIIITLAFGYVRIKRERKTFHTRIADIYDDLKFTYTKGLIPGLLLSVILGGLGISIPLGLLAIIAVITAAAAFTLRANWMSAAYIVSVSMLIGFGLQIYQAEPFLERFPQGFAVVWPAVAVFLGLLIITEGAVAYRSAHVRTSPALVVSSRGLPIGQQLANRVWLLPLFLLVPGNGLESHLSWWPVFTVPGGSFHFLWIPYFVGFGQRVQGSLPETSIRITAKRVCILGLAVAVLGAASLLWTPLAGAAVCTALLGRIFLSIKQRVNDNAAPFYFSKRDQGLMVLGIIPNTPAEDLELKIGEIITKVNGIPVKNVSDFYEALQHNRAYVKLEIIGLNGEIRFDQRASYEGEHHELGILFVKDDREDEAVASGS
What is the function of this protein?
The main function of the Min system is to promote the disassembly of the cytokinetic ring after cell division, thereby ensuring that division occurs only once per cell cycle.  MinJ acts as a bridge between DivIVA and MinD.  May modulate activity and localization of MinD and MinC through direct interaction with MinD.
What are the official names of this protein?
Cell division topological determinant MinJ.
What is the protein family that this protein belongs to?
Belongs to the MinJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localization depends on DivIVA and on the state of the cell cycle. Present at both cell poles in non-dividing cells. As cells prepare to divide, moves from poles to mid-cell. Then, after division is completed, stays associated with new poles, but also moves back to old poles.
Protein: PYRB_VIBVY
Sequence: MTNSLYKKHIISIPELSRAELELIVKTAGQLKAEPNPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGDVIGFDDGGNTSLAKKGETLSDSVQVISNYVDAFVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTLLDLFTISETQDRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFFFVAPDALAMPDYILEDLDEAGISYSLHTDMETVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLEGARENLKVLHPLPRVDEITTDVDKTPHAYYFQQAGNGVYAREALLALVLNESL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y2289_ALKMQ
Sequence: MGKSQYVTGIKKMPINERPREKLLNYGPESLSNPELLAIILSTGTKEMSAIDLATHVLSYSEEGLRHLKNCEIEELQQIKGVGIAKASQILAAVELGKRISLTSRVNHYRIKSPDDVSNLLMEEMRYLKKEYFNIALLNTKHEVIAIENISIGSLNASIVHPREVFVVAIKRSSSAIILVHNHPSGDPSPSGEDIRITKRLVEAGKLLGIEVLDHIIIGDNVYYSLKEKSMM
What are the official names of this protein?
UPF0758 protein Amet_2289.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: CHVI_SINFN
Sequence: MQTIALVDDDRNILTSVSIALEAEGYKVETYTDGASALEGLLARPPHLAIFDIKMPRMDGMELLRRLRQKSDLPVIFLTSKDEEIDELFGLKMGADDFITKPFSQRLLVERVKAILRRAPARDAAAAGVAGAAKSADAPSRSLERGQLVMDQERHTCTWKSEPVTLTVTEFLILHSLAQRPGVVKSRDALMDAAYDEQVYVDDRTIDSHIKRLRKKFKMVDVDFDMIETLYGVGYRFRESA
What is the function of this protein?
Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan.
What are the official names of this protein?
Transcriptional regulatory protein ChvI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_XANAC
Sequence: MSFNFRIGQGYDVHAFGPGDHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDARWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIADLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAAPHQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RUVA_DEHM1
Sequence: MISSLSGILEASGKDWAVINVSGVGFRTYMPASSPALIGELGQRVRVFTHLHVREDALNLFGFGTAEELSLFETLIDVSGIGPKLGLAMLSAMNAEALASAIISGNTELLSTIPGVGKKTASRIVLELKDKITKSWEAGVLIQVTEANSDILATLTALGYSAGEAAKAIASLEDITGMPLEERIKLALNYFNNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RS15_ECOHS
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: OBG_LEPBJ
Sequence: MESFVDEVAIEVFAGHGGAGSVHFRREKYVEFGGPDGGDGGTGGNVIIRPNLSMYTLDKYLSKRKFKAEAGFPGVGDNCSGKKGEDLILFVPLGTQIYDEETGDLLFDFVTDTQEFVVARGGRGGKGNTHFKSSTNQTPRFAQPGEEGEYKFLRLSLKLLADVGIVGLPNAGKSTLISKITDAHPKIAGYAFTTLSPNLGVVKRRGDIFRFTIADIPGIIEGASMGIGLGLSFLRHIERVKGILYLFDASSLDIEEDLKMLRNELFTYNPELLNRPYLIVLNKIDIWDDPEFTKDIISKIIHLGKVIAISADKETNLEKLLEAMDEAFFKDEIEKVLKSTKELKSVSLNESDILGSFENSREIKE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_CORJK
Sequence: MGRRGVTKKRNRIDRVKTRVVVLGSTGSIGTQALEVMADNPERFELVGISAHGSKPDVLAQQVRDFGLDLGRVAVASEHTAEWLDGEFGAHCIRGKDSARELVEAVGPELGECDVILNALVGSLGLDATLATLGTKAKLALANKESLVAGGQLVLKAADEGQLIPVDSEHSAMAQCLRSGRVDEVDSLVLTASGGPFRGYTRAQLEDVTPLQAANHPTWSMGQMNTLNSATMVNKGLELIEASLLFGIPAEKIDVTVHPQSIVHSMVTFIDGATIAQASPPSMKLPISLALGWPDRIADAQPKLDFTEATDWHFEPLDDEVFPAVILARQAVTAGGTMPAVYNAANEEAAVEFLNGRLSFPRIVDTVAATMEACQHLSAEPNDLEDVLAAEREARAKAHERMATWLSD
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ISN1_SCHPO
Sequence: MASRYRVEYALKQHRKDDFIEWIKGLLSVPFVLQAGTPSQKLVTREKEQETLERYAVILRDVEKLIEAHIQIVSEGGSYSQLKMLVPSITIFWTPLPLVKAMYALEPKLCLAKRSFVAPSFNDVRAILGGAQLNYLADNGLDMVSFDGDVTLYEDGQPLLPDNPVISRLIQLLSRGIYVIILTAAGYPSRTGQEYTDRFSGLLQAIEDSDLKDGQKRKLHVLGGESNYLFAYDPLHGLQWVDADSWMLPVMKTWPHDEILEILDTAEETLRSCIQGLNIDAKIVRKERSVGFVPSLGQKLRREQLEEAVLETQATLQIRNFSVPFTAFNGGNDIWCDIGDKKLGVLCLQHFFNISHPSRCLHVGDQFLSAGNNDYKARAAATTVWVSSPHETIEFLDYYFSFLKK
What is the function of this protein?
IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.
What are the official names of this protein?
IMP-specific 5'-nucleotidase 1.
What is the protein family that this protein belongs to?
Belongs to the ISN1 family.
Protein: GUAC_YERPY
Sequence: MRIEEGLKLGFKDVLIRPKRSTLKSRSEVALERQFTFKHSGWNWSGVPIIAANMDTVGTFRMAEVLASFDILTAVHKHYTLEQWAEFVKRSPESVLRHVMVSTGTSSADFDKMKQILALSPSLKFICIDVANGYSEHFVSFLQRAREACPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCSVPGDVAKAFGGGADFVMLGGMLAGHDECEGRVVEENGEKFMLFYGMSSESAMKRHVGGVAQYRAAEGKTVKLPLRGSVDNTVRDIMGGLRSACTYVGASHLKELTKRTTFIRVAEQENRVFGTD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: SSH4_NEOFI
Sequence: MRGSEASGPGAIFGAPSTLTTSVIRNPTSFLSSSTPLPSTDADVVAQNVEHVLLSLTSHNDGGLVGVSGNSSGSTGKGILIGVLSAFGSATVAVLVLAIFFFFKYTRRGRIFLDRIGRPGEFDDEQAFAREEAEALEVMDDMSRSEYMRAKSFVEANPPESMQTDISLSQFLAIQEKGVSAWEFQPELEIANCFVEGRTEIEFYDSECSVQTNLPVPKQNDVYYWEAKIYEKPESTHISIGMTTKPYPLFRLPGFHKTSVAYLSTGHRRYNQPFSATPYGPPLAQGDVVGVGYRPRSGTIFFTRNGKKLEDVVHGAKTQNFFPTVGANGPCTVHVNFGQMGFVFIEANVKKWGLAPMTGSLAPPPPYGSEQGSILLESGRESAAQISQRVYQDARTNSTVRIPPSRSPGPVRSPTDISLAPLAHIPSHEDVGEGSSHANTIADEQTPLLNTSDLDQVPPPEYSSPDGSRRGSDITGDLPNQNSPPIPSYDAAVGNQADNTSTPDGDH
What is the function of this protein?
Components of the endosome-vacuole trafficking pathway that regulates nutrient transport.  May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).
What are the official names of this protein?
Protein ssh4.
What is the protein family that this protein belongs to?
Belongs to the SSH4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: H1C2_TRYCR
Sequence: MFCVLKFLSCTLSRINIVQKLSDAAVPPKKAAPKKAVAKKTPAKKTAKKPAVKKPAAKKRAAPKKKPAAAKKAVTKSAKKHAAKKAPKKAVKKAPKK
What are the official names of this protein?
Histone H1.C2.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SPART_DROME
Sequence: MAEEESEFLEAYAGIRTAYKAAMTQVDLAVSHEEQESPGQAIVAYELALRMIEDTFGIPVGLPNKIDTVQAEWNDACALIQKLKSAETELRYRLKVLRSQKQSIDDSAVEATEESRAEMDTKRPPLLAENPSTQYGIANASGAPKTYRELAAGLRELLAVRDAKVLLDELFRAQVKMYRIEASGSVTTISGSSTMSLVMCTVGGKWKYLSGIYFIQCSMPNEGTAGIWLYPLVPSITNCYQTEYGAFIFPDMECQQPGNAFGLMLTKEGQTSRTEDELEDLQQFFLDLLEAVLAGTVVQLKSPTSQRAGLASDTVSGSEQVSRHIVSAADFIASNLVRGAEKTGGFMLRSTPYIISKMTPASMDAQVPSSVQTSVEVAQKVTHAAAGMTGWIAGKVGTASMAVGRYLAPHIQEQGSKLLQKGFGYDTSEANSTMEGAMTIAAGAVEGVSTVFDGLETSAKILGSSLSENSVKIIEHKYGQQTGNLASGTFDTVGNVFVVSQNVNYITPKGIAKKMVKRTGEAVVSDYKRDLRKSESHYINAGSLYPDLRALKE
What is the function of this protein?
During postembryonic development, functions with endocytic adapter Eps-15 in neurons to restrain synaptic growth, by inhibiting BMP signaling, and to control synaptic endocytosis.  Required presynaptically for neuromuscular junction (NMJ) neurotransmission.  Inhibits neuronal BMP signaling by promoting endocytic internalization and subsequent endosomal trafficking of the BMP receptor wit.  In this way, regulates the Fmr1 translational regulator controlling Futsch expression to modulate neuronal microtubule stability, which controls both synaptogenesis and neuronal survival.
What are the official names of this protein?
Protein spartin.
What are the subcellular locations of this protein?
Presynaptic cell membrane. Early endosome. Lipid droplet. Note=Colocalizes with Eps-15 at presynaptic cell membrane.
Protein: GSXL1_ARATH
Sequence: MTSVITSRARHVAVIGLGAAGLVAVRELRREGHTVIGFEREKHVGGLWVYTDRVDSDSVSVDPDRTIVHSSIYQSLRTNLPRECMGYSDFPFVTRSSDGDPRRYPDHREVLMYLQDFAKEFKIEDMIRFETEVLCVEPSPENNRKWRVQFKSSNGVSGEEIFDAVVVCNGHFTEPRLAHIPGIESWPGKQIHSHNYRIPDPFKDEVVIVIGSQASGNDISTDIATIAKEVHISSKMVASDSYGCYDNLRIHPTIYRAREDGSVVFRNGKVVFADAIVHCTGYKYHFPFLKTSGYVTVEDNRVGPLYKHVFPPALAPGISFIGLPFMGLQFFMFEIQSKWVASVLSGRVKLPAEDKMMEEAVAFYSKLEDLGIPKRYTHFLTDPRGNPMLGTFKPEDAVVISQSDYFNWIAKQCGCTSIERWRERLYNVAIKKVFFGGDSYRDRWDDDQLIEEVYREFAKLKPNQDCSS
What is the function of this protein?
Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
What are the official names of this protein?
Flavin-containing monooxygenase FMO GS-OX-like 1, Flavin-monooxygenase glucosinolate S-oxygenase-like 1.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: RNP2_METMA
Sequence: MKRLLPSLRAKKRYLAFELISEEPASRSDIVKEVMSSASSLLGDVTTSDCDIRVLGFENGKGIIQCSHTKVKQTRASLAALTRINGKRATLHVLGVSGTVKRATEKFLQDEGVFSS
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_GLOVI
Sequence: MNAQEIIRSIEAEQMKTQLPVLHIGDTVKVNVRIREGGKERIQAFEGTIISMARAGINRTVTVRRIFQGIGVERVFLVHSPRIESMTVTRLGKVRRAKLYYLRDRIGKATRVKQKITRKAN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HEMO_DANRE
Sequence: MRLIQALSLCLALSLSLAAPPQHKEDHSHKGKPGGEGHKHELHHGAQLDRCKGIEFDAVAVNEEGVPYFFKGDHLFKGFHGKAELSNKTFPELDDHHHLGHVDAAFRMHSEDSPDHHDHQFFFLDNMVFSYFKHKLEKDYPKLISAVFPGIPDHLDAAVECPKPDCPNDTVIFFKGDEIYHFNMHTKKVDEKEFKSMPNCTGAFRYMGHYYCFHGHQFSKFDPMTGEVHGKYPKEARDYFMRCPHFGSKTTDDHIEREQCSRVHLDAITSDDAGNIYAFRGHHFLSITGDKFHSDTIESEFKELHSEVDSVFSYDGHFYMIKDNDVFVYKVGKPHTHLEGYPKPLKDVLGIEGPVDAAFVCEDHHVVHIIKGQSIYDVDLKATPRKLVKEGTITQFKRIDAAMCGPKGVTVVIGNHFYNYDSVQVMLMAKIMPEQQKVSQQLFGCDH
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HMUI_BPSP1
Sequence: MEWKDIKGYEGHYQVSNTGEVYSIKSGKTLKHQIPKDGYHRIGLFKGGKGKTFQVHRLVAIHFCEGYEEGLVVDHKDGNKDNNLSTNLRWVTQKINVENQMSRGTLNVSKAQQIAKIKNQKPIIVISPDGIEKEYPSTKCACEELGLTRGKVTDVLKGHRIHHKGYTFRYKLNG
What are the official names of this protein?
DNA endonuclease I-HmuI, HNH homing endonuclease I-HmuI.
Protein: CMTA5_ARATH
Sequence: MAGVDSGKLIGSEIHGFHTLQDLDIQTMLDEAYSRWLRPNEIHALLCNHKFFTINVKPVNLPKSGTIVLFDRKMLRNFRKDGHNWKKKKDGKTIKEAHEHLKVGNEERIHVYYAHGEDTPTFVRRCYWLLDKSQEHIVLVHYRETHEVHAAPATPGNSYSSSITDHLSPKIVAEDTSSGVHNTCNTGFEVRSNSLGSRNHEIRLHEINTLDWDELLVPADISNQSHPTEEDMLYFTEQLQTAPRGSVKQGNHLAGYNGSVDIPSFPGLEDPVYQNNNSCGAGEFSSQHSHCGVDPNLQRRDFSATVTDQPGDALLNNGYGSQDSFGRWVNNFISDSPGSVDDPSLEAVYTPGQDSSTPPTVFHSHSDIPEQVFNITDVSPAWAYSTEKTKILVTGFFHDSFQHLGRSNLICICGELRVPAEFLQMGVYRCFLPPQSPGVVNLYLSVDGNKPISQLFSFEHRSVQFIEKAIPQDDQLYKWEEFEFQVRLAHLLFTSSNKISVLTSKISPENLLEAKKLASRTSHLLNSWAYLMKSIQANEVPFDQARDHLFELTLKNRLKEWLLEKVIENRNTKEYDSKGLGVIHLCAVLGYTWSILLFSWANISLDFRDKQGWTALHWAAYYGREKMVAALLSAGARPNLVTDPTKEFLGGCTAADLAQQKGYDGLAAFLAEKCLVAQFKDMQTAGNISGNLETIKAEKSSNPGNANEEEQSLKDTLAAYRTAAEAAARIQGAFREHELKVRSSAVRFASKEEEAKNIIAAMKIQHAFRNFEVRRKIAAAARIQYRFQTWKMRREFLNMRKKAIRIQAAFRGFQVRRQYQKITWSVGVLEKAILRWRLKRKGFRGLQVSQPDEKEGSEAVEDFYKTSQKQAEERLERSVVKVQAMFRSKKAQQDYRRMKLAHEEAQLEYDGMQELDQMATEES
What is the function of this protein?
Transcription activator (PubMed:14581622).  Binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity).  Regulates transcriptional activity in response to calcium signals (Probable).  Binds calmodulin in a calcium-dependent manner (By similarity).  Involved in response to cold.  Contributes together with CAMTA3 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986).
What are the official names of this protein?
Calmodulin-binding transcription activator 5, AtCAMTA5, Ethylene-induced calmodulin-binding protein f, EICBP.f, Signal-responsive protein 6, AtSR6.
What is the protein family that this protein belongs to?
Belongs to the CAMTA family.