PharMolix/UniProtQA huggingface dataset:
Protein: PSBI_ILLOL
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREEEE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CYB_SORVA
Sequence: MTNLRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGVCLIVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVIPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NANE_CLOD6
Sequence: MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRAQGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRVRPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEGPDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVKAIEIN
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: SYA_FRACC
Sequence: MDTAEIRSRFLNHFARRGHTVVPSASLVAQDPTLLLVNAGMVPFKPYFLGDLPAPWPRAASVQKCVRTVDIENVGHTARHASFFQMCGNFSFGDYFKAEAIPFAFELLTEGFGFKADDLWATVYLDDDEAEGIWRKLLPAERIQRRGKEDNFWSMGVPGPCGPCSEIYFDRGCAYGREGGPIADEERYLEVWNLVFMQYERGEGAGYDYPIERELPARNIDTGMGLERMATILQGVDNLYEIDISRPVLDAAGRLTGRRYGADPADDVRLRVIADHTRTAAMLISDGVVPSNEGRGYVLRRMLRRAIRNARLLGAHEPVMSELFAVVGSAMGTIYPELLDNAETITGVAVAEEQAFAETLRTGTTIFDTAARQARSLGSTTLGGEAAFKLHDTYGFPIDLTLEMAAEAGLSVDEAGFRRLMDRQRQAAKADRAARRIGNVDLSAFRPILARSGPTTFTGYEELSRTSGVVGLVGIADGAGLAAAGEDTEVGVVLDATPFYAESGGQEPDLGRLRFDGGEVEVLDVQRPVPDLVLHRVRVLGGELRLGVEVFAEVDADRRRAVSRSHTATHLVHTAFRRALGEGATQAGSLNSPGRLRFDFHALGAVPPSVLADVEDEINEVALRDLPVRAFVTTQEEARRLGAMALFGEKYGDAVRVVDVGDYARELCGGTHVASSAQLGAVKLLSEASISAGTRRVEGLVGLDAFRYLAREHLLVSQLSTALKARPDELVDRVTDIVGRLRDAERELERLRAAAVLAGAGALAEGAEEVAGVAVVTAEVPAGTAPDDVRLLALDVRGRLAGRPAVVAVAKADGSSIVVVTDDAARGRGLRAGDLVRQSWASLGGKGGGKPDVAQGGGGNPQLVPAVFARLRGLVAEHASR
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_LEGPC
Sequence: MRTRVIVNGANGKMGILACETLENHEQFEVVAKLSRQDNLGQSILDTKAQIVVDLTRADCVYENSLTIINHGARPVIGTSGLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMMLATKASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKPKNKLPLKELTPGARGGSHHDINIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRHCFMPGIVLACQKVLNLTNLVYGLEHLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_STRPQ
Sequence: METWQEVTVHVHRDAQEAVSNLLIETGSQGVAIADSADYIGQKDRFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQGTDNIHVAAGDLLKEVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_PSEA8
Sequence: MAVYAVGDLQGCLDPLKCLLERVAFDPAKDRLWLVGDLVNRGPQSLETLRFLYAMRESVVSVLGNHDLHLLAVAHKSERLKKSDTLREILEAPDREPLLDWLRRLPLLHYDEQRKVALVHAGIPPQWSLEKARLRAAEVEQALRDDQRLPLFLDGMYGNEPAKWDKKLHGIDRLRVITNYFTRMRFCTEDGKLDLKSKEGLDTAPPGYAPWFSFPSRKTRGEKIIFGHWAALEGHCDEPGLFALDTGCVWGARMTLLNVDSGERLSCDCAEQRAPARPAATPA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: FTHS_AGARV
Sequence: MKTDIQIAQEATMLPIKDVAASIGIEEDDLELYGKYKAKISDELINRTKKNPDGKLILVTAINPTPAGEGKTTTSVGLGEAFGRLGKKALIALREPSLGPCFGIKGGAAGGGYAQVVPMEDLNLHFTGDFHAITSANNLLAALLDNHIQQGNELGIDPRQIVWKRCMDMNDRVLRNIVVGLGSKMDGMVREDHFVITVASEIMAILCLADDMADLKKRLGRIIVAYTFDGKPVTADDLQATGSMAALLKDALKPNLIQTLEHTPAIVHGGPFANIAHGCNSVRATKTALKLADYVITEAGFGADLGAEKFFDIKCRMAGLKPDAVVLVATIRALKYNGGVPKDELSSENLDALKAGIVNLEKHIENLHKFGVPVVVTLNSFVTDTKAETDFVEQFCKERGCEFALSEVWEKGGEGGIDLANKVLETIEHKESNFKVLYDDSLSLKEKIETVAKEIYGADGVTYSPAAERELKRITDLGMGDFPVCMAKTQYSLSDDAKKLGRPSGFKINVREVYASAGAGFVVAVNGSIMTMPGLSKKPAAYGIDVDDNGVITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RF1_UREU1
Sequence: MEYNKKLYEAIERVAVKNKTLKQELETITSDFKKIKEINIQLKKTTKIAEAFAKYKQKIDAGIVAEELLNTEKDLELVELAQMDLDDAKASIPVIENELKIMLLPTDPNDDKNVIVEMRPAAGGDESSIFVGNLFDTYRAYTESNNWKMKIIEMTPNAVGFSFISFMISGEEVYSRMKFESGVHRVQRVPATESKGRVHTSTITVAVLPEQDEVDVVINPSDLRIDTYRASGAGGQHVNRTESAVRITHIPTGVVAACQEGKSQIENRETAMKMLRAKLWEAAQEQQNAEFANLRKNQVGTGDRSEKIRTYNYPQNRVTDHRISLTLNKLDQIMMGELDEIIDALITDEQTNLMANLGI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H13I1_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWPIAYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1g, U7-TRTX-Hhn1g, Hainantoxin-XIII-9, HNTX-XIII-9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RISB_BACCZ
Sequence: MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RUVB_SHEHH
Sequence: MIEADRLIHPQIIDREEAEAVDRAMRPKMLDEYTGQDDTRAQLKIFIEAAQKRGEALDHMLIYGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLEPNDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIPLRLEFYNVKDLSSIVARSAKVMALEIDDEGAVEIARRSRGTPRIANRLLRRVRDFAEVKHSGDVTKVIAEAALDMLDVDAEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIATPRAYNHFNIIKPDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ULAG_ECO45
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGANVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGTLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLP24_CAEEL
Sequence: MRIEKCYFCSSPIYPGHGIQFVRNDSTVFKFCRSRCNKLFKKKKNPRKLRFTKAARRARGKELINDATQLLEQRRDEPVKYERAMFQKTIEAAKTISALKTKRYGNLIRKRLQPGKIVQKKGLLAKVDKKMHLIRAPVANRDGVKTRAAAKEKKTAESMETN
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  Ensures the docking of NOG1 to pre-60S particles (By similarity).
What are the official names of this protein?
Probable ribosome biogenesis protein RLP24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MQO_ECOUT
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: ASP1_ANISI
Sequence: MMFTPLIVLTLLVLATAEHQCGPNEQWSDCPGCELQCGESDKPCPAMCGDPKCYCSPDQYRRIPDGRCIRKIQCPQH
What is the function of this protein?
Defends the organism against the host's proteinases.
What are the official names of this protein?
Serine protease inhibitor 1, ASPI-1.
What are the subcellular locations of this protein?
Secreted.
Protein: P9_WTV
Sequence: MSGKIQDGVAIRRMSDAILFFTNYTSRNLIDQRDITLSTLHTIRRNLGTCWSIALLNCWNETSSHAGVMRFILDIAFSLRFGDFTMLGACGNVDPFDDAGQIFLKSCKATGRNDSCFLTPSDNFGYYLVSFLNKEQLKCVVDMNVGIHNIEDIYVTRMESIMEFIYYYYTESGRDVVNWLEKLESADAGLAAHAKSKRLMRAEIDLIRREILERTRLFINNNRNSFHDHHRELVRRYRTIWADVISDGDVVEETSTEATTSAQHSTALSAELDEVDEYDHPNDGLLTFRREEDAASNLDSLLGSLSGEDAFQG
What is the function of this protein?
Minor outer capsid protein.
What are the official names of this protein?
Minor outer capsid protein P9, Non-structural protein 11, Pns11.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus minor outer capsid protein P9 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Found in the peripheral regions of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: BCHG_CERS4
Sequence: MSVNLSLHPRSVPEPRALLELIQPITWFPPIWAYLCGTVSVGIWPGEKWPLVLLGMVLAGPLVCGMSQAANNWCDRHVDAVNEPDRPIPSGRIPGRWGLYIALLMTVLSLAVGWMLGPWGFGATVFGVLAAWAYSVEPIRLKRSGWWGPGLVALCYEGLPWFTGAAVLSAGAPSFFIVTVALLYAFGAHGIMTLNDFKALEGDRQHGVRSLPVMLGPEVAAKLACTVMAMAQILVITLLVIWGKPIHAGIITALLVAQLFAMRVLLRDPAGKCPWYNGTGVTLYVLGMMVAAFAIRGLEVLP
What is the function of this protein?
Catalyzes the esterification of bacteriochlorophyllide a by geranylgeraniol-PPi.
What are the official names of this protein?
Bacteriochlorophyll synthase 33 kDa chain, Geranylgeranyl bacteriochlorophyll synthase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: B2MG_CHISA
Sequence: MARLVVVALLVLLCLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNDKDEYACRVSDVTFTAPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGC_BUCAP
Sequence: MLNVLIVGASGYSGAELVNYINRHMFSKIKKIFVSENSSHIGKLFSELHQEFKNIIDLPFEAINYDTLIEKDIDAVFLATDHHVSYSLVPFFLSLNCVVFDLSGAYRVKNTDTYLKYYGFSHQHQDILKRSVYGLAEWNKQEIKKAELIAVPGCYATCIQLALKPLIKENFLNDEFIPIINAISGVSGAGRKANITNSFCEVSLHPYNVFTHRHTPEIIEHLGIPVIFIPHLGSFSRGILASITCKLKCNFTFQDIYNLYNTVYKEKPLIRVYEKNFPSIKAVVKLPFCDIGFIIQDKYIVIIAAEDNLLKGAAAQAIQCFNIRFGFSEIESII
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_XYLFM
Sequence: MELILLQKVANLGALGDKVTVKPGYGRNFLLPNGVAVPATEANLAAFQAKRAEYEAKAKSELDQAQARAAKFEGASVTVSAHASTEGKLYGSVGARDIAEAFTAVGLPLEKKEVILGEGAFRLIGEYDVLLHLHADVESTVKVIVQGVP
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SYE_MAGMM
Sequence: MRTRFAPSPTGFLHVGGARTALFCHLQARHVGGTTVLRIEDTDRERSNQALVDAILDGLHWLGLDPDEGPLFQSDHTQRHTDMALKLLEEGKAYKCYCTKQELDDMRAAQQARKEKPRYDGRCRHRSEPPSDQPYVIRFKTPLEGEVVWPDMVQGTIHIANKELDDLILLRSDGSPTYNLAVVVDDHDMEITHVIRGEDHTSNTPRQIHLFQALGWDVPSYAHIPLLHGEDGSKLSKRHGAVSVLQFREEGFLASALNNYLVRMGWSHGEKEEFTMDEMVALFDVNNVGRSAAIFNTSKLLWLNGVHIRQSGPEQLRGELMWHLQRLGVDNPNPNFIDQIIPGMQERVKTMLEMAQMAMFYFKAPTEYAETAVAKHLHADILPAYAALLEKLHTVTADEWDNGGLERAFKVVMAETGAKMGKIGQPVRIAISGSDIAPGIYDILQLVGRHESLRRLEVLLSFFQQRVHGANG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSPA_ECOLI
Sequence: MSTRREVILSWLCEKRQTWRLCYLLGEAGSGKTWLAQQLQKDKHRRVITLSLVVSWQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLIIIENAHLNHRRILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSIGRLTEHELKASILEGQNIDQPDLLLTARVLKRIALLCRGDRRKLALAGETIRLLQQAEQTSVFTAKQWRMIYRILGDNRPRKMQLAVVMSGTIIALTCGWLLLSSFTATLPVPAWLIPVTPVVKQDMTKDIAHVVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLACKSGNASLQTLVDQNLPWIASLKVGDKKLPVVVVRVGEASVDVLVGQQTWTLTHKWFESVWTGDYLLLWKMSPEGESTITRDSSEEEILWLETMLNRALHISTEPSAEWRPLLVEKIKQFQKSHHLKTDGVVGFSTLVHLWQVAGESAYLYRDEANISPETTVKGK
What is the function of this protein?
May play a regulatory role under conditions of derepressed gsp gene expression.
What are the official names of this protein?
Putative general secretion pathway protein A.
What is the protein family that this protein belongs to?
Belongs to the ExeA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TGT_MOOTA
Sequence: MPAVTFTVLKRDRSTGARLGRLTTPHGTIETPVFMPVGTQATVKTMTPEEVAGLGAEIILANTYHLYLRPGADIIREAGGLHRFMHWERPILTDSGGFQVFSLADLREISDEGVTFRSHLDGSIHFLGPAESMAVQEALGSDIAMAFDECVAYPASPEEVAAGVERTSRWAEACLRAHRREDQAVFGIIQGGTIPELRRRSAREITALDFPGYGIGGLSVGEPKELMYSILEELQGYLPENKPRYLMGVGSPDCLIEGVKRGVDMFDCVLPTRIARNGTVMTTYGKLVVRNAAYARDFRPLDPECDCYTCRNYTRAYIRHLLKAEEILGLRLTTIHNLHFLIKLMQRLRQAIAEGRLEEVAADFYERYNSGKI
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: LMRA_BACSU
Sequence: MSYGDSREKILSAATRLFQLQGYYGTGLNQIIKESGAPKGSLYYHFPGGKEQLAIEAVNEMKEYIRQKIADCMEACTDPAEGIQAFLKELSCQFSCTEDIEGLPVGLLAAETSLKSEPLREACHEAYKEWASVYEEKLRQTGCSESRAKEASTVVNAMIEGGILLSLTAKNSTPLLHISSCIPDLLKR
What is the function of this protein?
Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons.
What are the official names of this protein?
HTH-type transcriptional regulator LmrA.
Protein: SYV_CLOTE
Sequence: MNDNINIAKTYDPKEFEERIYKMWEEGEYFTPKVDKDKKPYTIVMPPPNITGKLHLGHALDNSMQDFLIRVKRMQGYSTLWLPGQDHASIATEVKVENELLKTGLKKKEMGREAFLERVWEWSEEYRGRIRDQLKKLGSSADFTRESFTMDDNLDKAVRAVFVKLYEEGLIYKGNRIVNWCPKCMTALSDAEIEYEENYGNFWHVKYPLVDSEEYLEIATTRPETMLGDTAVAVNPNDERYKHLIGKKLMLPLVNREIPIVADDYVDVEFGTGAVKITPAHDPNDYEVGKRHDLEEIIIMNENGTINELGGKYSGMDRYEARKAIVEDLKKEGFLVKVKEHIHNVSCHDRCNTIIEPMISKQWYVKMKELAKPAIEVVKSGEIKFVPERFDKTYFNWMENIQDWCISRQLWWGHRIPVWYCKDCGETIVSLEEAKKCSKCSSENLIQDEDVLDTWFSSALWPFSTLGWPDKTEDLEYFYPTDVLATGYDIIFFWVARMIFSGLHNMKEIPFKTVLIHGIVRDSEGKKMSKSLGNGVDPLEVIDKYGADALRFMLITGNAPGNDIRFYEERVESARNFANKIWNASRYVMMNLDKNLMEKYKDCKDYNIADTWILSRLNEVIKEVTDNIEKFELGMASQKVYDFMWNEFCDWYIELSKPVLYGEDEKAKGVTFNVLFNVLTSGLKLLHPIMPFITEEIFINIQEEEKTITTSKWPEFKEELKNEEVEKKMSHVIEAIKAIRNVRIEMDVPPSRKAKIMIYALDGIDAFKDGKIYFEKLASASEVEFLNSKEEAPENAVSAVTKGAEIYIPLFDLVDLEKEMERLNKEREKLEKEIERVDKKLSNENFVKKAPEAVVNEEKAKGEKYKEMLEAVLERIKSLK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDKA_PASMU
Sequence: MLEFKHKNTFFLFNFKQPKAQQACFFRSSFWKKQARILGSAQGRGVTWFLQTKDLFGVNAALKHYYRGGLWGKINRDYYRFSTLSNARSFAEFSLLKQLHEAGLAVPKPLGACVEKVAFGFYRADLLTEKIEHAQDLTVYLQQGKLTEQDWHKVGQLIHQLHSLQVCHTDLNAHNILVQQRDDGRKFWLIDFDKCAHQLGERWKSENLNRLHRSFMKEVTRMKIQFSEQDWQALLAGYQA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLPP_PHOLL
Sequence: MSYSDKRDQYAPHMALVPMVVEQTTRGERSYDIYSRLLKERIIFLTGQVEDHMANLVAAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRICLPNSRVMIHQPLGGFQGQATDIEIHAQEILKVKSRMNELMAKHTGRPIEEIAKDTERDRFLSADEAVEYGLVDKIFTHRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.