PharMolix/UniProtQA huggingface dataset:
Protein: LEU3_WICAN
Sequence: MSEKTIVVLPGDHVGTEITNEAIKVLKAIEEVRPNVKFNFQHHLIGGAAIDATGVPLPDEALEAAKKADAVLLGAVGGPKWGTGAVRPEQGLLKIRKELNLYANLRPCNFASESLLELSPIKAEFAKGTDFTVVRELVGGIYFGERKEDDGSGVASDTETYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVTETIEKEFPQLTVQHQLIDSAAMILIKSPTTLNGIVITSNMFGDIISDEASVIPGSLGLLPSASLASLPDTNKAFGLYEPCHGSAPDLPANKVNPIATILSAAMMLKLSLDLFEEGVALEKAVKEVLDAGVRTGDLRGSNSTKEVGDAAVEAAKRILKN
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_AERHH
Sequence: MTPKEFKRLYRIISILLEQGIDELVPARYQPWPGRLARRSLFWLKNKRQGLNRGARIRLAFEALGPIFIKFGQMLSTRRDLLPPDIAEELALLQDRVPPFCGQAARRQIEASLGCTIETLFDDFDETPLASASIAQVHTARLKENGREIVIKVIRPDIEPVIEADLRLMQALARLVARFVPQSGRLRPIEVVEEYRKTILDELNLMREAANAIQLRRNFTGSEALYVPEVFTEHCREQVLVMERIYGIPVSDIAALEANGTNMKLLAERGVEVFFTQVFRDSFFHADMHPGNIFVSYEHPENPLWIGIDCGIVGTLNREDKRYLAENFLAFFNRDYRRVAELHVESGWVPPDTKVDEFEFAIRTVLEPIFEKPLSEISFGHVLLNLFNTARRFNMQVQPQLVLLQKTLLYVEGLGRQLYPQLDLWQTAKPYLENWMYQQVGPKAVWNAIKEKAPFWAEKLPELPELVYETLRQTRHQQRHFDQMFADFRRHSRRQGQARYLLGVGASLLLAGVFLLTQKQHIEWGQISLAGAGLCWLLGWLRTRSH
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIDI_ECOLI
Sequence: MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTFESIVADKTAEIKRGLLAGIKGEKITTVEKKEDVDVDKILNQSGIALAIAALLCAFIGGMRKENRWGIRGALVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV
What are the official names of this protein?
Inner membrane protein YidI.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_SYNJA
Sequence: MVKLRLKRYGKRRQPTYRIVAIESKARREGRPLEELGYYNPRTKETVLETAGLLKWLRCGAQPTDTVDSLLRKAGIYEMLKAGEGGVVAAIRIPAIAKPEAGIPDPAPSTEEPAAVCEASAEMAGQPGEVEPAGAAAEPNSQEPEPEEEKPQVEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NADE_BURP0
Sequence: MSRPDQAARRRAIAAELHVSPTFDARDEAERRIGFVADYLRTAGLRACVLGISGGIDSSTAGRLAQLAVERLRASGYDARFVAMRLPYGAQHDEADARRALAFVRADETLTVDVKPAADAMLAALAAGGLAYLDHAQQDFVLGNIKARERMIAQYAVAGARNGVVIGTDHAAESVMGFFTKFGDGGADVLPLAGLTKRRVRALARMLGADEPLVLKTPTADLETLRPQRPDEHAYGITYEQIDDFLEGKPMDDAVAETVLRFYDATRHKRALPYTMFDWPGHPA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PYRR_MYCBT
Sequence: MGAAGDAAIGRESRELMSAADVGRTISRIAHQIIEKTALDDPVGPDAPRVVLLGIPTRGVTLANRLAGNITEYSGIHVGHGALDITLYRDDLMIKPPRPLASTSIPAGGIDDALVILVDDVLYSGRSVRSALDALRDVGRPRAVQLAVLVDRGHRELPLRADYVGKNVPTSRSESVHVRLREHDGRDGVVISR
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: SCUB1_HUMAN
Sequence: MGAAAVRWHLCVLLALGTRGRLAGGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAGGVESCFLSCPAHTLFVPDSENSYVLSCGVPGPQGKALQKRNGTSSGLGPSCSDAPTTPIKQKARFKIRDAKCHLRPHSQARAKETARQPLLDHCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEIETKMEEASDTCEADCLRKRAEQSLQAAIKTLRKSIGRQQFYVQVSGTEYEVAQRPAKALEGQGACGAGQVLQDSKCVACGPGTHFGGELGQCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSECGGQCSPGFFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHEGTTSFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCITCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK
What is the function of this protein?
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
What are the official names of this protein?
Signal peptide, CUB and EGF-like domain-containing protein 1.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein.
Protein: RS9_STAES
Sequence: MAQVEYKGTGRRKNSVARVRLVPGEGNITVNERDVRDYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: IL1RA_HUMAN
Sequence: MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm.
Protein: Y2098_MYCMM
Sequence: MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGAMADPGSVSYLFSRKGVVTLEKNGLTEDDVLAAVLEAGAEDVNDLGDSFEVISEPGELVAVRSALQDAGIDYESAEAGFQSSVTVPVDVDGARKVFKLVDALEESDDVQNVWTNVDVSDEVLAELDEE
What are the official names of this protein?
Probable transcriptional regulatory protein MMAR_2098.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEF1_ASPFU
Sequence: MPVVKGGVWTNIEDEVLRAAVSKYGLNQWARVSSLLARKTPKQCKARWVEWLDPGIRKVEWSREEDEKLLHLAKLMPTQWRTIAPIVGRTATQCLERYQKLLDEAEARENDELGLGGPSGGEAAAPSADDVRRLRPGELDPDPESKPARPDTIDLDEDEKEMLSEARARLANTQGKKAKRKARERQLEESRRLAVLQKRRELKNAGINIKVVTRKKGEMDYNADIPFEKPAAPGFYDTTEEEARNERQREMFDPRKQQLANKRKGDQEEDADRKKRKNDKNGSSAFAAAARAGQMQKIREAEQSSKRRALVLPAPQVSESEMEDIIKMGMAGDRASKMSGDDETTRGLIGNYTSIVGGTPIRTPRAPPEEDHIANEIRNIRALTETQSSLLGGENTPLHEGGSSTGFDGIAPRRQQIVTPNPMATPFRQANGLGATPLHGGIGPGATPLRTPRDQFALNQMEGGQLIGTTPRDIRLHQKAVSQAIRSKLASLPKPKETEWELEELPSESAEPTVAAEISEEDAAERDRREREARERAAQAELKRQTQVYQRGLPRPSVLDIDALMARASQVTDPINGMIAKEAALLIANDAQKFRLPNGKVEGKARKLERLNDELIEAARAAIVAEVASSNQQQEWLQGFDDRWSSTHSNALPGLANYGDDDEDENMYRQEQRMIDAFENVQASLLATAERGNKLEKKLALHYGGYQNRAKTLRTKIVEASSALENSKYELNAFQTLQISEESAISRRLEKLRDDVAFVLKREREAQETYRIRKEELDELVAGTEAVVNGWH
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor cef1.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: REG5_PYRHO
Sequence: MKKRKLSKKDWEIIKLLKKDARMSDAEIGRRIGLSKSAVRWRRINLQKRGYLLISAYLRFDKLGYTYAFVLVKIKPDTPRNEILKFKKALMENEHTFEIYEVLGDYNVLIGVFGEDVSELKRNIQELIIGQKCVQEYKVLLGAKSLKGLEVPFWDALED
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PH1055.
Protein: HSLO_GEOSW
Sequence: MSDYLVKALAYDGQVRAYAARTTDTVSEAQRRHQTWPTASAALGRAITAGVMMGAMLKGDDKLTIKIDGGGPIGTILVDSNAKGEVRGYVTNPHVHFDLNEHGKLDVAKAVGKNGMLTVVKDLGLRDFFTGQVPIISGELGEDFTYYFASSEQVPSSVGVGVLVNPDNTILAAGGFIIQLMPGTEEKTIEQIEQRLQTIPPVSKMVESGLTPEEILEELLGKGNVKVLETLPVSFVCRCSRERIADAIISLGPQEIQDIMEKEGYAEASCHFCNETYHFTKEELEQLKQLAEAKN
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORB_STAAN
Sequence: MEKPSREAFEGNNKLLIGIVLSVITFWLFAQSLVNVVPILEDSFNTDIGTVNIAVSITALFSGMFVVGAGGLADKYGRIKLTNIGIILNILGSLLIIISNIPLLLIIGRLIQGLSAACIMPATLSIIKSYYIGKDRQRALSYWSIGSWGGSGVCSFFGGAVATLLGWRWIFILSIIISLIALFLIKGTPETKSKSISLNKFDIKGLVLLVIMLLTLNILITKGSELGVTSLLFITLLAIAIGSFSLFIVLEKRATNPLIDFKLFKNKAYTGATASNFLLNGVAGTLIVANTFVQRGLGYSSLQAGSLSITYLVMVLIMIRVGEKLLQTLGCKKPMLIGTGVLIVGECLISLTFLPEILYVICCIIGYLFFGLGLGIYATPSTDTAIANAPLEKVGVAAGIYKMASALGGAFGVALSGAVYAIVSNMTNIYTGAMIALWLNAGMGILSFVIILLLVPKQNDTQL
What is the function of this protein?
Multidrug efflux pump that acts independently of NorA and is one of the factors that confers resistance against diverse quinolones and chemical compounds.
What are the official names of this protein?
Quinolone resistance protein NorB.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_HELHP
Sequence: MILSIESSCDDSSLALMSINDASLLYHIKLSQDEEHSTYGGIVPEIASRLHAQRLPEILKKLKAFLNNDLSPIKAVAVTTRPGLSVTLIEGLMMAKALCLGLQVPLICVNHLKGHIYSLLIHKATSDMQAILPKNTSLPQPLGILLVSGGHTQILHMRDFNAISLIAQSLDDSFGESFDKVAKYLGLGYPGGPVIESYATTFMRDFPHIAPHSFPVPLLHNQKLQFSFSGLKNAVRLAIQALPQPLSLKDRGSICAGFQQSACEHIVRKVRLYFQSAQAQDLEHFAIVGGASANTYLRTTLNELCEEYNKQLHLADLAFCADNAAMIGVCAIEHYKRGDFTPIDEAQISPKSLLNDFL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F50AB_XENLA
Sequence: MAQYKGAASEAGRAMQLMKKREKQREQLEQMKLKIAEENVVKANINKKFSAHYDAVEAELKSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQFKDLQLKLEKQRERERKKEQKRKIASLSFNLEEDEECEDEESEEEEEEYVADKEDLPKKKKKKKQQLGKNPDVDTSFLPDRDREEEENRLREELRQEWERKQEKIKSEEIEITFSYWDGSGHRRTVKMKKGNSIQQFLQKALEILRKDFSELRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHEDVRLLSDASVEKDESHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR
What is the function of this protein?
Probably involved in the regulation of pre-mRNA splicing.
What are the official names of this protein?
Protein FAM50A-B.
What is the protein family that this protein belongs to?
Belongs to the FAM50 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_PARPJ
Sequence: MANVVENLGKLERRVTISLPKDAVQKEVDSRIRQLAKNVRMPGFRPGKVPLKMVTQQYSGQVEAEVLSDKVGKEFFDISRSENLRVAGQPSFAPKSDATEGDYAFDATFEVYPEVKLGDVATAEIERTTTTISEAEIDRTLDILRKQRVHFHARGEAGEHGDGGGDTAAKEGDRVTVDFVGKIEGEVFQGGSADDFAFVLGEGRMLPEFEKAATGLKVGESKEFDLAFPEDYHGKDVAGKTAQFTITMKKIEWPHLPEIDAEFAKSLGIEDGDLTKMRAEIKDNLEREAKRRTQAIVKNQVMDALLKISELDVPNALIEQDQERLVAMARQDLEQRGVPNAKDAPIPAAMFKEQAERRVKLGLVLAELVKANELQAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAYVVEANVVDFVLSKAKVTDKEVSFEELASATAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LKHA4_KLULA
Sequence: MLFNFYNKTSAACKSLPAKALSNVRYFQTSPISRKMPLPPVLESRRPKESPEFDYSTLSNYKSFKVKHSQLDVSVDFKKKTISGSVSYEIEKVKKDENTIKLDTSYLKISKVKVDDEDDVKFKLLERKHPLGAQLIVSPSSLPEIFHLCLQFSTTADCTALQWLDEHQTSGKPYVFSQLEAIHARSLFTCFDTPSVKSTYLANIKSELPVVFSGIQTGYDDSTKVYSFKQEVPIPAYLIGIASGDLASADIGPRSKVYVEPYRLKDAQWEFDGDVEKFITTAEDIIFKYEWGTYDILVNPNSYPYGGMESPNMTFATPTLIAHDKSNIDVIAHELAHSWSGNLVTNCSWDHFWLNEGWTVYLERRITGAIHGEATRHFSSLIGWNDLEGSISAMQNPERFSCLVQNLKDGTDPDNAFSTVPYEKGSNLLFYLENLLGGKEVFDPFIKHYFTKFARQSLDTWQFLDALFEFFHDKREILESVDWQTWLFTPGMPPKPKLITDLADDVYALANKWIASAQKFTEREQFEKEFSIKDISEFSSNQIVLLLDTLVQGGMPEKDTFKWSNYPEASEIFTDIYEDKISKSQNAEVIFRNYRLQVKSHITSSYPELAEWLGTVGRMKFVRPGYRLLNEVDRELAIKTFHRFRDSYHPICKSLVKQDLGI
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ALR_HUMAN
Sequence: MAAPGERGRFHGGNLFFLPGGARSEMMDDLATDARGRGAGRRDAAASASTPAQAPTSDSPVAEDASRRRPCRACVDFKTWMRTQQKRDTKFREDCPPDREELGRHSWAVLHTLAAYYPDLPTPEQQQDMAQFIHLFSKFYPCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRKLGKPDFDCSKVDERWRDGWKDGSCD
What is the function of this protein?
May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
What are the official names of this protein?
FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion intermembrane space. Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Secreted.
Protein: COQ1_YEAST
Sequence: MFQRSGAAHHIKLISSRRCRFKSSFAVALNAASKLVTPKILWNNPISLVSKEMNTLAKNIVALIGSGHPVLNKVTSYYFETEGKKVRPLLVLLLSRALSEIPMTERNHLKIDKSDVPEDPIYSKPSQNQLFQRPASSISPLHILHGIKPLNPLTKGPEPLPEETFDKQRGILPKQRRLAEIVEMIHTASLLHDDVIDHSDTRRGRPSGNAAFTNKMAVLAGDFLLGRATVSISRLHNPEVVELMSNSIANLVEGEFMQLKNTSIDADIDTIENGHKLLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRCAAILSGASPAVIDECYDFGRNLGICFQLVDDMLDFTVSGKDLGKPSGADLKLGIATAPVLFAWKEDPSLGPLISRNFSERGDVEKTIDSVRLHNGIAKTKILAEEYRDKALQNLRDSLPESDARSALEFLTNSILTRRK
What is the function of this protein?
Assembly of polyisoprenoid side chains.  The polyprenyl synthase of coenzyme Q biosynthesis catalyzes the formation from isopentenyl diphosphate of all trans-polyprenyl pyrophosphates generally ranging in length of between 6 and 10 isoprene units depending on the species.
What are the official names of this protein?
Hexaprenyl pyrophosphate synthase, mitochondrial, HPS.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RIMP_ANADF
Sequence: MPGIAEESIAERTRRVLEPVLARDGYELVEVEWLRQGSRWTLRLFVDKPGGVGIEDCQAVSRLVDPILDVEDFIEPAYDLEVSSPGLDRPLRKPADFDRYAGQRAHVKAYGPVAGTAPGSPARKNWTGVLVGYRDGAVEIDVDGVVHRVPHDQIAKAHLEYDFEADLRRKD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_PSESM
Sequence: MSVPFDPASYDRQLEEKTARLRELLAPFDAPEPQVFDSPREHYRLRAEFRLWREDQKRYYAMFAPGDNKTPILLEGLPIASQRINALMPVLRERWEASPTLNHKLFQVDFLTTLAGDAMITMCYHRPLDDEWLAAAEQLAVELDVSLIGRSKGQKLIIGHDYVTEKLDVAGRTFSYRQPEGAFTQPNGTVNGKMLNWAFDALGERQDDLLELYCGNGNFTLPLATRVRKVLATEISKTSVNAALSNLDDNGVDNVTLVRLSAEELTEALNEVRPFRRLQGIDLKSYDFGSVFVDPPRAGMDPDTCELTRRFERILYISCNPETLAANIAQLYDTHRIERCALFDQFPYTHHMESGVLLVRR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: LIVB3_BRUME
Sequence: MNLKLLSSVAFAATIGFASAAYADITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDGQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGLE
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: SUFS_KLEP3
Sequence: MTFSVERVRADFPVLNREVNGQPLAYLDSAASAQKPEAVIGAEAEFYRHGYAAVHRGIHTLSAEATARMEAVRQQAANFLNAGSAEEVVFVRGTTEGINLVANSWGNANVGAGDNIIISEMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLDVVPGLFDPRTRLLAITEVSNVLGTENPLAALIALAHQHGAKVLVDGAQAVMHHPVDVQALGCDFYVFSGHKLYGPTGIGVLYGRSELLQAMAPWEGGGSMIATVSLTEGTTWNRAPWRFEAGTPNTGGIIGLGAALTYVSQLGLTQIAEYEQTLMRYALEALRAVPDLILYGPAQRKGVIAFNLGQHHAYDVGSFLDNYGIAVRTGHHCAMPLMARYQVPAMCRASLAMYNTTEEVDRLVAGLQRIHKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYE_ASPOR
Sequence: MYQKLLLVPLLLTSALASPHDASSHQKFHQLNERAAFPIPASKGSQTFKEPYYVKGTYDGGMKTFGRGVKCTGQKEGGDKDAVFIVADGGILRNAIIGADQIEGVHCEGSCTIENVWWQEVCEDALTFKGTGTGVHKVIGGGAQGADDKVIQHNSGGSAIIQDFTVQNFGKLYRSCGNCKKQFKRTVQISGVKASNGKTLVGINPNLGDSATIDGCASSVKEICVEYEGTDNNGKEPKKAHSGPSNTCKFKEPLASC
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase E.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VIF_SIVEK
Sequence: MENRWQVMVVWQVDRMRVRTWNSLVKHHMYVSKKARGWFYRHHYETDNPKISSEIHIPLGEAKLVIVTYWGLMPGERPWHLGHGVSIEWRQGIYRTQIDPELADKLIHLYYFDCFTASAIRQAVLGRPVIPKCEYPAGHKQVGSLQYLALIAWVGVQKRRPPLPSVTKLTEDRWNRHQKIKDHRGSHTTNGL
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: RNPA_CHLCV
Sequence: MHRSTLPKYARVLKRKQFLYISRAGSHCQGSQVIFHVAPSRYSGCCKLGITVSKKFGKAHKRNYFKRIVREAFRKKRHSLPACQIVVMPKNKQQPKFEDLLQDFAQQIPEALSSKLAKNKPTTGVEYSPKNEKCESVLP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PL3_LUPLU
Sequence: GIFTFEDESTTTVAPAKLYK
What are the official names of this protein?
Protein PR-L3.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: Y1496_PYRFU
Sequence: MKELDQILEKCAEEIDPLSHEIAERIRKLKNLPKDEMFLEYLRIIDFTSTTKIPWRKKNYILIILWKYGEKIERLLYSRLEHFGRANVPKRYFRLVDGKILSMLFLVFILFPAFTSHIWSFRLGYEEIQVGKEITFNENLCEYRTAWLYDFKASMVCTIKYGYGKVNIRLNSTNPMEAGVEVQRFISQIPYDYARLESGFSYIQTPRETIGRRIGVCSDFAILTAQVLLDNNVSPVYIIHTLFKGDITGGHATAALFINGTLWIFDWGSAPVTFSEYLDTIDRLWEVREVRVYRLTESSIVLDRVYKGEPESDAWRYVYTLTMLIGIFIIKRREWLWI
What are the official names of this protein?
UPF0252 protein PF1496.
What is the protein family that this protein belongs to?
Belongs to the UPF0252 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.