PharMolix/UniProtQA huggingface dataset:
Protein: Y1614_ARATH
Sequence: MDFLFLLLERKNKHMGKKRVVLLWLSIFISFSSAEITEESPLSIGQTLSSSNGVYELGFFSFNNSQNQYVGISFKGIIPRVVVWVANREKPVTDSAANLVISSNGSLQLFNGKHGVVWSSGKALASNGSRVELLDSGNLVVIEKVSGRTLWESFEHLGDTLLPHSTIMYNVHTGEKRGLTSWKSYTDPSPGDFVVLITPQVPSQGFLMRGSTPYFRSGPWAKTKFTGLPQMDESYTSPFSLTQDVNGSGYYSYFDRDNKRSRIRLTPDGSMKALRYNGMDWDTTYEGPANSCDIYGVCGPFGFCVISVPPKCKCFKGFIPKSIEEWKTGNWTSGCVRRSELHCQGNSTGKDANVFHTVPNIKPPDFYEYADSVDAEECQQNCLNNCSCLAFAYIPGIGCLMWSKDLMDTVQFAAGGELLSIRLARSELDVNKRKKTIIAITVSLTLFVILGFTAFGFWRRRVEQNALISEDAWRNDLQTQDVPGLEYFEMNTIQTATNNFSLSNKLGHGGFGSVYKGKLQDGREIAVKRLSSSSEQGKQEFMNEIVLISKLQHRNLVRVLGCCVEGTEKLLIYEFMKNKSLDTFVFDSKKRLEIDWPKRFDIIQGIARGLLYLHRDSRLRIIHRDLKVSNILLDEKMNPKISDFGLARMFHGTEYQDKTRRVVGTLGYMSPEYAWAGVFSEKSDIYSFGVLLLEIISGEKISRFSYGEEGKTLLAYAWECWCGARGVNLLDQALGDSCHPYEVGRCVQIGLLCVQYQPADRPNTLELLSMLTTTSDLPLPKQPTFVVHTRDGKSPSNDSMITVNEMTESVIHGR
What are the official names of this protein?
G-type lectin S-receptor-like serine/threonine-protein kinase At1g61400.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MUTS_SALPB
Sequence: MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLDRLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWTLNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1457_METJA
Sequence: MMVMTALTLLILFFGLAFILVGFGLILGYLIFSRKNKTVNGTANRTVVVERDSSNLLGTAAAVAGGVIAGELITDAIEDVINNNENNEADGYNSEGIETTIEDTIEEIDKGVDNVIEDITDEIDNITNDIGDSFF
What are the official names of this protein?
Uncharacterized protein MJ1457.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASSY_IDILO
Sequence: MSNVKKVVLAYSGGLDTSAIVPWLKENYGCEVVAFVADVGQGAEELEGVEEKAKASGASECHVVDLKDEFVKNYVYPTLKTGAIYEGTYLLGTAMARPIIAKAQVEVARKVGADALSHGCTGKGNDQVRFESCYAALAPDLQVIAPWREWELSSRESLLGYLAERNIPCSASATKIYSRDANAWHISHEGGELEDPWCEPTEKVWTMTASPEQAPDKPEYLCVTVENGEIVAVNNQALSPFECLSVLNDVAAKHGVGRVDIVENRLVGMKSRGCYETPGGTVMMAALQAIDELVLDKVSRSWKTQLSEQFAQLLYDGRWFTPLQQSVMAAAQSLCATASGEVVLKLYKGSVTAVQKRSPHSLYSEDFATFGADEVYNQAHAEGFIRLFSLPSRIAALQKQQKG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_RHIME
Sequence: MKITDLAGSNFPELSAQLKGDAATIEIGGITADSRQVKPGDLFVAVAGSKADGAAYIADALSRGASAVVAGTGTPAEAGAPVFAISDPRRFLAKAASSFYGRQPETMVAVTGTAGKTSVASFTRQIWAHSGFSAAMIGTTGVVAPGRTEYGSLTTPDPVSLHKLLAELADEGVTHAAMEASSHGLDQRRLDGVELAAAAFTNLGRDHMDYHPTVEHYMASKMRLFGALLPKGSPAVIFADDQWSAEAIAAARKAGHDVRTVGRNGDFIALKRVEHFRHKQSAEVHVGDDIYEIHVPLAGDFQIANALVAAGLAMSTGITAKAAFSALERLQGASGRLELVGQTKDGALAYVDYAHKPDALANVLESVRPFTTGRVVVVFGCGGDRDKGKRPIMGEIASRLADVVIVTDDNPRSEVPEVIRAEIMAAAKGATEIGDRAEAIRAAVGMLKTGDTLIVAGKGHEEGQTVGSVTLPFSDHAEVRKALGGL
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF4_SHVX
Sequence: MVIVTTFHIDAARDRIINCVKDVRNIVTNQVVPATRKLGSIETTLENFRTETIGGFTTISDCVSLLRNLRSETTRNFNTLLSRTAEPTGQAQTQLRQGFDEPDGHKSEQRTFFSNLDTALNATQALLNHVPPARYTLPPAPLPVNESFGQLHALHLNTLEWLTHINHNLDSMLNMLNPANLMSQGTPLSRLKDAVRTLTQNMNTIQSDQQKILASTSATNHSDILRKLESLDTGLKQLGIRLDVVVSSLNNMSERPPTPSHDTASSSTSTDPNPLPPYQAVHPSLFCRTYGNILYNGIDSRIPMDVTGRPASTSLKLTITVECSEQNTRVNFTLLDDGYILLSDSIETKHKLQHIPSDCLSLIHARCPKFVYKFRGEGLC
What are the official names of this protein?
Uncharacterized ORF4 protein, 42 kDa protein.
Protein: PVK2_PARSA
Sequence: GSSGLIAFPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TNR6_MACFA
Sequence: MLGIWTLLPLVLTSVVRLLSKCVNAQVTDISSKGFELRKIVTTIETQNLEGLHHEGQFCRNPCPPGERKARDCTVNEDEPDCVPCQEGKEYTDKGHFSSKCRRCRLCDEGHGLEVEINCTRTQNTKCRCKPNFFCNSAVCEHCDPCTKCEHGIIEECTLTSNTKCKEEDSRSDLPWLCLLLLLIPPIVYVVIKKACRKHRKENQGPHESTTLNPETAINLSDVDLSKYITTIAGAMTLSQVKDFVRKNGVSEAKIDEIKNDNVQDTAEQKVQLLRNWYQLHGKKDACDTLIKGLKTADLCTLAEKIHAVILKDITSDTENSNFRNEIQSLV
What is the function of this protein?
Receptor for TNFSF6/FASLG.  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.  FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Protein: DAP2_YEAST
Sequence: MEGGEEEVERIPDELFDTKKKHLLDKLIRVGIILVLLIWGTVLLLKSIPHHSNTPDYQEPNSNYTNDGKLKVSFSVVRNNTFQPKYHELQWISDNKIESNDLGLYVTFMNDSYVVKSVYDDSYNSVLLEGKTFIHNGQNLTVESITASPDLKRLLIRTNSVQNWRHSTFGSYFVYDKSSSSFEEIGNEVALAIWSPNSNDIAYVQDNNIYIYSAISKKTIRAVTNDGSSFLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIPYYVQDEKDIYPEMRSIKYPKSGTPNPHAELWVYSMKDGTSFHPRISGNKKDGSLLITEVTWVGNGNVLVKTTDRSSDILTVFLIDTIAKTSNVVRNESSNGGWWEITHNTLFIPANETFDRPHNGYVDILPIGGYNHLAYFENSNSSHYKTLTEGKWEVVNGPLAFDSMENRLYFISTRKSSTERHVYYIDLRSPNEIIEVTDTSEDGVYDVSFSSGRRFGLLTYKGPKVPYQKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKDEFGKDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLVRDRLGDYEARDQISAASLYGSLTFVDPQKISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQENFDGYVESSVHNVTALAQANRFLLMHGTGDDNVHFQNSLKFLDLLDLNGVENYDVHVFPDSDHSIRYHNANVIVFDKLLDWAKRAFDGQFVK
What are the official names of this protein?
Dipeptidyl aminopeptidase B, DPAP B, YSCV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: PDXJ_CAMJJ
Sequence: MLLGVNIDHIAVLRQARMVNDPDLLEAAFIAAKHGDQITLHVREDRRHAQDFDLENIIKFCKSPINLECALNDEILNLALKLKPHRVTLVPEKREELTTEGGLCLNHAKLKQSIEKLQNANIEVSLFINPSLEDIEKSKILKAQFIELHTGHYANLHNALFSNISHTAFALKELGQDKKTLQTQFEKELQNLELCAKKGTELGLKVAAGHGLNYKNVKLIVKIKEICELNIGQSIVARSVFTGLKNAILEMKELIKDEKTSH
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUL6_CAEEL
Sequence: MSIEAVWGTLQDGLNLLYRREHMSKKYYMMLYDAVYNICTTTTLANSNNNSPEFASEFLYKQLENYIRTYVIAIRDRISACSGDELLGKCTIEWDNFKFSTRICNCIFQYLNRNFVSKKVEDKNGEIVEIYKLALDIWKAEFFDNFKVKTIDAILELILLERCGSTINSTHISSVVECLTELDIYKVSFEPQFLDATKLFYKQEVLNSKETVIEYMITVENRLFQEEYRSRRYLGPSTNDLLIDSCESILISDRLKFLHSEFERLLEARKDEHLTRMYSLCRRVTHGLEDLRVYLEKRILKEGHETLQRLAKDSGLKTTPKEYITKLLEVHEIYFNLINKAFDRNALFMQSLDKASKDFIEANAVTMLAPEKHRSTRSADYLARYCDQLLKKNSKVQDETALDKALTVLKYISEKDVFQLYYQNWFSERIINNSSASDDAEEKFITNLTATEGLEYTRNLVKMVEDAKISKDLTTEFKDIKTEKSIDFNVILQTTGAWPSLDQIKIILPRELSTILKEFDTFYNASHNGRRLNWAYSQCRGEVNSKAFEKKYVFIVTASQLCTLYLFNEQDSFTIEQISKAIEMTAKSTSAIVGSLNPVIDPVLVVDKGNEKDGYPPDAVVSLNTKYANKKVRVDLTTAIKKATADRETDAVQNTVESDRKYEIKACIVRIMKTRKSLTHTLLINEIISQLKSRFTPNVQMIKICIEILIEQLYIRRSENEHNVYEYLA
What is the function of this protein?
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Cullin-6.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: CALM_OREMO
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRYVMTNLGEKLTDEXVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: TRPV1_RABIT
Sequence: MKRWVSLDSGESEDPLPEDTCPDLLDGDSNAKPPPAKPHIFSTAKSRSRLFGKGDSEETSPMDCSYEEGELAPCPAITVSSVIIVQRSGDGPTCARQLSQDSVAAAGAEKPLKLYDRRRIFEAVAQNNCQELESLLCFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHSGQNDTIPLLLEIARQTDSLKEFVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTPDNTKFVTSMYNEILILGAKLHPTLKLEELINKKGLTPLALAAGSGKIGVLAYILQREILEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCERNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRVVKRIFYFNFFVYCLYMIIFTTAAYYRPVDGLPPYKLRNLPGDYFRVTGEILSVAGGVYFFFRGIQYFLQRRPSMKALFVDSYSEMLFFVQALFMLATVVLYFSHCKEYVATMVFSLALGWINMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKNSSTSAESTSHRWRGFGCRSSDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKSIWKLQRAITILDTEKGFLKCMRKAFRSGKLLQVGYTPDGKDDCRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSGRVSGRNWKNFALVPLLRDASTRDRHPXPPEDVHLRPFVGSLKPGDAELFKDSVAAAEK
What is the function of this protein?
Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli (PubMed:14996838, PubMed:11035011).  Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons.  Involved in mediation of inflammatory pain and hyperalgesia.  Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL.  Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin.  Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects.  Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity).  Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state.  Mild extracellular acidic pH (6. 5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel (By similarity).
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 1, TrpV1, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mostly, but not exclusively expressed in postsynaptic dendritic spines.
Protein: FPG_MARN8
Sequence: MPELPEVETTRQGIAPHCEGQTIQRVIVRNPSLRWPVPADLAEHLEGKTIRAVERRAKYLFLHLETGSVIVHLGMSGSLRVITDDSPAMTHDHVELVLGNHRRLRFNDPRRFGCWLWTTDWNRHPLISALGPEPLSEDFNGAWLFRLSRQKQTPVKSFIMDNHVVVGVGNIYANEALFKAGIHPKRKAGRISLDRYHKLAEAIRETLSAAILMGGTTLRDFVNSDGKPGYFAQSLLVYGKAGAPCTECNTPLKEIRMNNRSTVYCPRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: FLGH_ECOBW
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: DCTA_ECO5E
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDALNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEPA_SALG2
Sequence: MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGCIIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDIASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGNDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: COX2_SOYBN
Sequence: MKFEWLFLTIAPCDAAEPWQLGFQDAATPMMQGIIDLHHDIFFFLILILVFVSRILVRALWHFHYKKNPIPQRIVHGTTIEILRTIFPSIIPMFIAIPSFALLYSMDEVVVDPAITIKAIGHQWYRTYEYSDYNSSDEQSLTFDSYTIPEDDLELGQSRLLEVDNRVVVPAKTHLRIIVTPADVPHSWAVPSLGVKCDAVPGRLNQISISVQREGVYYGQCSEICGTNHAFTPIVVEAVPSKDYGSRVFNQLIPQTTGEA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RR4_BUCRO
Sequence: MSRYRGPRVKIIRRLGALPGLTNKIPQLKSGYTNQSVSNKKISQYRIRLEEKQKLRFHYGITERQLLKYVRIARGAKGSTGQISLQSSEMRLDNIIFRLGIAPTIPGARQLVNHRHILVNNNIVNIPSYRCKPQDFITIKNSQKSQTIITKNIELSQKYQIPNHLTFNSLEKKGLVNQILDRESIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y547_ALISL
Sequence: MDLKNHFLVAMPSMNDPVFTRSVIYICEHDSDGTMGLRINQPVQISLKGMLDQIKLDNPSPIIFPQTLSQPVLNGGPVSDDRGFVLHYPKDNYSSSIEVTEELSVTTSKDILATLGTEDQPYKYLVALGYSGWDAGQLEQELSENTWLILEADSSVIFDTPIPDRWRRAIEILGISPVNISSEVGHA
What are the official names of this protein?
UPF0301 protein VSAL_I0547.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: TX1C_CHEPU
Sequence: MKFSLFFSVFFLAVLHACLSESEIDLEDEEHFMSSDSFLSEIQDESRGKTCIERNKECTNDRHGCCRGKIFKDKCTCVKSGKTEKCVCTQKKWAKIIESYIGDIPALPKPVDDKCVPKHADCSKRKDDCCKGGIFKYQCKCYDMYDDDGEKTDLCGCVSPVEHQAIEGALRIAKKLIGDRWGR
What is the function of this protein?
Spider venom toxin that exhibits cytolytic activity by forming an alpha-helix across the membrane (PubMed:20657014).  Lethal to insect larvae (PubMed:20657014, PubMed:24717175).  Causes instant paralysis and death in the larvae of the flesh fly (S. carnaria) at doses of 20 ug/g, at doses of less than 10 ug/g causes reversible paralysis (PubMed:20657014).  Has cytolytic activity against insect Sf9 cells (PubMed:20657014).  Causes stable and irreversible depolarization of fly muscle fibers, leading to contracture at higher toxin concentrations (PubMed:20657014).  Destabilizes membranes (PubMed:20657014).
What are the official names of this protein?
DELTA-miturgitoxin-Cp1c, DELTA-MGTX-Cp1c, Toxin CpTx1, Toxin CpTx1c.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. Double-CSTX subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Probably forms a transmembrane alpha-helix in the target cell membrane.
Protein: YCJF_SALCH
Sequence: MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESRTFAPAAIDERPEDEGVAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGLQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARELLHSHSVGKGRAFCEKLAQQAGIDQSHPALQRWYAAIHETQNDREVVGLYAHLVQPVLDAQARREISRFAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDNDKPRLGDFRRQLIGQLKETLQKSKSSPEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AMO_KLEOK
Sequence: MAILSPRKTALALAVALSCAWQSPAFAHGGEAHMVPMDKTLQDFGADVQWDDYAQMFTLIKDGAYVKVKPGAKTAIVNGKTLELQVPVVMKDGKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNSLSAAEISAAVAIVKAAADFKPNTRFTEISLREPDKKAVWDFALNGTPVNAPRAADVIMLDGKHVIEAVVDLQNKKVLSWTPIKDAHGMVLLDDFASVQNIINASSEFAEVLKKHGIDDPSKVITTPLTVGYFDGKDGLKQDARLLKVVSYLDVGDGNYWAHPIENLVAVVDLEQKKIIKIEEGPTIPVPMAARPYDGRDRVAPKIKPLDIIEPEGKNYTITGDMIHWQNWDFHLRMNSRVGPILSTVTYNDNGKKRQVMYEGSLGGMIVPYGDPDVGWYFKAYLDSGDYGMGTLTSPIVRGKDAPSNAVLLDETIADYTGTPTTIPRAIAIFERYAGPEYKHQEMGKPNVSTERRELVVRWISTVGNYDYIFDWVFHENGTIGIDAGATGIEAVKGVQAKTMHDPSAKEDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNTLVAMDPEVKPNTAGGPRTSTMQINQYTIDSEQKAAQKFDPGTIRLLSNITKENRMGNPVSYQIIPYAGGTHPVATGAKFAPDEWIYHRLSFMDKQLWVTRYHPTERFPEGKYPNRSIHDTGLGQYAKDDESLDNHDDVVWITTGTTHVARAEEWPIMPTEWAHALLKPWNFFDETPTLGEKKE
What is the function of this protein?
Active on tyramine, tryptamine, beta-phenethylamine and dopamine.
What are the official names of this protein?
Primary amine oxidase, Monamine oxidase, Tyramine oxidase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GSA_SALDC
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_PLETE
Sequence: MNAEIVVNNSNFSSNTPPFLKKQPEIRRYIIQGSRRFSNYWWAFIVCLGSIGFLLTGISSYFEFQNLLHLQNYFSFANEAQSSLNKVELPIILFFPQGLVMCFYGILGLFLSFYLWFSIFLNIGAGFNEIYIYTGETLKTENQYSKSINSNNLKANNWNSSKIKSNLKKFTKMKDTQTIDYSSENELKNQLTNPNSAVCKFAKGGSEVGCWEQSALTPLPPTPLSHIRIFRWGFPGKNRKINLQYSIDQISAIKLEFLQGFNSKRTICLKLSDQREILLTGSPQGDWETFEQLEKQASELAKFLKVNLEFSS
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.