PharMolix/UniProtQA huggingface dataset:
Protein: UBQL2_HUMAN
Sequence: MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNAAGTNTTSASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPEMMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSSSGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAAANYVASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANPQLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGVGVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSSAAPSETTSPTSESGPNQQFIQQMVQALAGANAPQLPNPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGSQPS
What is the function of this protein?
Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and the endoplasmic reticulum-associated protein degradation (ERAD) pathway.  Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (PubMed:10983987).  Plays a role in the ERAD pathway via its interaction with ER-localized proteins FAF2/UBXD8 and HERPUD1 and may form a link between the polyubiquitinated ERAD substrates and the proteasome (PubMed:24215460, PubMed:18307982).  Involved in the regulation of macroautophagy and autophagosome formation; required for maturation of autophagy-related protein LC3 from the cytosolic form LC3-I to the membrane-bound form LC3-II and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:19148225, PubMed:20529957).  Negatively regulates the endocytosis of GPCR receptors: AVPR2 and ADRB2, by specifically reducing the rate at which receptor-arrestin complexes concentrate in clathrin-coated pits (CCPs) (PubMed:18199683).
What are the official names of this protein?
Ubiquilin-2, Chap1, DSK2 homolog, Protein linking IAP with cytoskeleton 2, PLIC-2, hPLIC-2, Ubiquitin-like product Chap1/Dsk2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cytoplasmic vesicle, autophagosome. Note=Colocalizes with a subset of proteasomes, namely those that are cytoskeleton associated or free in the cytosol. Associated with fibers in mitotic cells.
Protein: SEPF_ACET2
Sequence: MSTILNKVLNFVGWETEDEEEDVETVEESEDVEEEESKKPQFIQPLSSRRTQNKVVNIHSASQFKVIVMQPESFNDAKDVCDHLKSKKPVVVNLGSVQKEVAQRIVDFLSGSVYALDGSIQKVSNDIFIVAPHNVDIMGDFKGDITGKAVFPWLK
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: MUTS_SYMTH
Sequence: MDPAKATPMFAQYLQIKEQYPDCILFYRLGDFYETFMDDAELVARELELVLTGRDAGKDMGRVPMAGIPYHAAEAYIARLIEKGYKVAICDQLEDPKKAKGLVKRDVTRVVTPGTLVEPRLLPEKANNFLAAIAWSRTGFGLAVVDLSTGEFAAAQMNGADSLRLLLEEIGRLEPREVILEPGLAAEPSVTGPLKASGIAVSVFEGRHFNHANAYRKLTEHFGTANLSGFGCEDLELATSAAGAALAYLEEMHKASLGHVSGLAVYYPGDYMVLDPATRRNLELTRSLRDGGRRGTLLWVMDRTVTAMGARLLKSWLERPLLDLRQIHARHEAVGELVHRPVLRADLRALLQEVHDLERLAGRVAVGSANARDLVALKQSLVALPSIRVALEDVRAERLVELRDQLDMLDDVRDLIEHAIADEPPVALTEGGILKDGFHPEVDELRRIARDGKAWIAQVEARERERTGIKSLKIGYNKVFGYYLAVTKPNLPLVPPDYIRKQTLANEERFITPELKELEEKVLHAAERVMDLEYELFVEIRQRVAAEVTRIQRSARAVAELDALASFAEVASLYGYCRPLVDGSTVLELKGSRHPVLERVMEEGAFVPNDLLVDTGENRVLLITGPNMGGKSTVMRQAALAVILAQAGSFVPAESAHIGLVDRVFTRVGASDDLATGRSTFMVEMTEVANILHSATERSLVVLDEVGRGTATFDGLSIAWAITEHIHQAIGCRTLFATHYHELCELEGILPGVKNYSVAVMEKGEDIIFLRKLVRGGADRSYGIQVGRLAGLPASVVERAREILATLEEQEGERKSRREAAAQRLRRQPAVQLTFFEPKKDPVVEELLGLNVMALTPIEALNTLYQLQAKAKENR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1250_STAAW
Sequence: MPIVNVKLLEGRSDEQLKNLVSEVTDAVEKTTGANRQAIHVVIEEMKPNHYGVAGVRKSDQ
What are the official names of this protein?
Probable tautomerase MW1250.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: PFKA_SHISS
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 1, ATP-PFK 1, Phosphofructokinase 1, 6-phosphofructokinase isozyme I, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ALISL
Sequence: MTGLERQLTEMLEAPVGALGYELVGLEFIRAGEHSTLRVFIDHENGIFVEDCAEASRQISAVMDVEDPITVAYNLEVSSPGLERPLFKAAHYQQFVGHEVSLVLKMPMNNRRKWKGDILDINGEIVTVTVDGNNEEFALSNISKANLVPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ECOLI
Sequence: MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVKISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
The C-terminal tail plays a role in the affinity of the 30S P site for different tRNAs.
What are the official names of this protein?
30S ribosomal protein S13, Small ribosomal subunit protein uS13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CDON_RAT
Sequence: MHPDLGPLWKLLYVLVILCSSVSSDLATYFISEPLSAVQKLGRPVVLHCSAKPVTARISWLHNGKRLDRNTEQIKIHRGTLTILSLNPSLSGCYQCVANNSVGAVVSGPATVSADALADFDSSTMHVITAEKKNTGFIGCRVPESNPKAEVRYKIRGKWLMYSTGNYIILPSGNLQILNVSSKDKGSYKCAAYNPVTSELKVEPAGRKLLVSRPSSDGFHILHPALSQALAVLPHSPVTLECVVSGVPASQVYWLKDGQDCLSGSNWRRLYSHLATASIDPADSGNYSCVVGNNSSGDVKHVTYTVNVLEHASISKGLHDQKVSLGATVRFTCEVHGNPAPNRTWFHNAQPIRPSSRHLTEGSVLKITGVIMEDSGLYQCMADNGIGFMQSTGRLQIEQDSGQRPVIVTAPANVEVTDGDFVTLSCNATGEPVPVIHWYGRHGLITSHPSQVLRSKSRKSHLFRPGDLDPEPVYLIMSQAGSSSLSIQAVTREHAGKYTCEAVNKHGSTQSEAFLTVVPFETNTKAEPVTPSEASQNDERDPRDGSESGLLNLFPVKVHSGGVELPAEKNASVPDAPNILSPPQTHMPDTYTLVWRTGRDGGMPINAYFVKYRKLDDGSGAVGSWHTVRVPGSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQASFPPVGIPKRPVTSEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTWIPRANGGSPITAFKVEYKRMKSSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIVINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPMKELSTPPSSSGNGGNVGPATSPARSSDMLYLIVGCVLGVMVLILLVFIALCLWKSRQQSAIQKYDPPGYLYQGSEINGQMVEYTTLSGTARINGSVHGGFLSKGSLSNGCSHLHHKGPNGVNGILNGTINGGLYSAHTSSLTRTCVEFEHPHHLVNGGAVYTAVPQMDPLECINCRNCRNNNRCFTKTNSPLPVVPVVASYPQDGLEMKPLGVMKFPVCPVSTVPDGGQIPEECLKDSVAPAPTQRTCRQDNTSDINSDSTEDTAEFNRGDSSGHSEAEDKVFSWSPLILSPVLEDCSEKTAWSPPGPPLDGLSVVLQQAQET
What is the function of this protein?
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells.  Promotes differentiation of myogenic cells (By similarity).
What are the official names of this protein?
Cell adhesion molecule-related/down-regulated by oncogenes.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: KR163_MOUSE
Sequence: MSYYSGYSGGLGYGYGGFGGLGCGCNSIRRLGCGCGSGSYGYGSGFGGFGYGSGFGGYGYGSGYGGYGYGCGRPSCCGGYGFSSFY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 16-3, Keratin-associated protein 16-10, Keratin-associated protein 16.3.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 16 family.
Protein: CYB_CYACA
Sequence: MVQFFKRPLLDIVHNHLIEYPTPVNIHYFWNFGFLAFICLAVQIITGIFLAIHYTPHVDLAFYSVEHIIRDVNYGWLLRYAHANGASIFFIIIYIHISRGLYYGSYVAPRHFTWVVGVFILLLIMATAFMGYVLPWGQISLWGATVITNLVSAVPLVGNSIVTWLWGGFSVDNATLNRFFSFHYLFPFIIVAIAFVHMAFLHQKGSGNPLGLIQPVDKISMYPYFIIKDAFGLVLFLLFFSLFVYFLPNLLGHPDNYIEANPIVTPNHIVPEWYFLPFYAILRSIPHKLGGVIAIIISILILAFLPWITNINVRSSLFRPLYKKLFWILFSIVLILGWIGGKPVEMPYVVIGQLITFLYFVYFLIFIPFLGRLEKFLVNYKTVY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PTH4_DANRE
Sequence: MLKMQRSQQRVALMMLMVVAAVHCQESESRRAVTEHQLMHDRGRSIQSLKRLIWLSSAIEGLHTAQARTLEPDSRWRSRGAQLYSQPGREESSGGQKRALETLLSDLYRAHLTFGLGEPEK
What is the function of this protein?
Neuroendocrine peptide which is produced by a subset of neurons in the hypothalamus.  Activates the G-protein coupled receptors pth1ra, pth1rb and pth2r with similar affinity.  Receptor binding stimulates intracellular cAMP production.  Plays a role in bone mineralization by regulating expression of factors involved in phosphate homeostasis.  Important for embryonic bone development.
What are the official names of this protein?
Parathyroid hormone 4.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: YL86_CAEEL
Sequence: MSGRYEVQNRYSAYIEARRNYLEQSESEEDIEVRTILRRPQIYSRRTVSTSSEEQPTTPAMVLVPTVTIQEAPKVVEIPTNGLPEPTPSSSVVQEIEILAPNEDEVKEEKPSDCTTCKKIENFVMPYYESLKAKYQQFVVRISDPALHATIRSEFAEYFPSVLLGFAIFFFGITFISFIKLLRGVSTQPSFFCRYFSGPFSPLFDALCEPDPYVLSEELPKVMSGLLDEMFITISEFFQTISKGFTVFGTLFTAIWHGLSENVFFGFHELGENLGENINHLLHFVVQFFHQIIHLILSSIATIAGAIAGVFTSVHDYLEPPQNVW
What are the official names of this protein?
Uncharacterized protein F54C8.6.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYL_ECO7I
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNNLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVIRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_PROA2
Sequence: MIITVLGAGSWGTTLAVLLANKGYAVSLWAHRPDFAQELARTRENVKYLPGVTFPDGLEIAQDINAAATDADVIVAAVPSQAVRETMELLAGINLDGKLMVNVAKGIELGSGKRLSEVILETLSGVDPSMVSVLYGPSHAEEVSGLQPTTVVAASSNLDTAKRVQEIFHTRMFRVYVNTDIVGVEIAGSVKNIIAIAAGIADGIGFGDNAKAAIITRGLAEISRLSAAMGGDPMTVSGLSGIGDLVVTCLSKHSRNRYVGEQIGKGRSLDDVISHMNMVAEGVLTTKAVVELSNRLGVDMPITRTVYAMLFEHKPVEDAILDLMTRDPKPEL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_METPP
Sequence: MSLQALYDVPAPAKLNLFLHVTGRRDDGYHLLQSVFALIDWADTLHFERRLDGRLVRHDLAAALPEDDLCLRAARLLQRESACPLGADISIDKDVPWGAGLGGGSSDAASTLLALNRLWGLHWSRERLLALGLQLGADVPFFVGGHNAWVEGIGERLTPIELAPRWWAVLKPAVAVPTVAIFGSPLLVRNTAAATISDFSANAVEFGHNDLQTPAMAYSDEVVQALALLQSRYGASRMSGSGSAVFAEAGTGESPTVAMMEAASLPPSWVGRMCRGLTVHPLALWAG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PYRI_SHIF8
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEEQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: YN8B_YEAST
Sequence: MSSSIFGPLTGFLERVNSLNAPYQALSYDEQKAMTIWQRVKFYNWTFELCALGVLFLVYAFYKFGNSVNLKRGNQIFQSLHSFLANDLKFSRVGFNINDSKIFTVEHQNTWFSSFATGRSAIKSINLNLHLVARSNPFSMCLEYLLGFFFASLKSKQLEEFMEIVIRPNGILVTSESAHPNKNAHEILTKFRFVTSIVNKEFMNQARTENYFLSIAHTSENDKLPNNFVYMSDVNQLSGFMFHYSKPYEVLSQAGNLLKYISFTDLPVNPPRDDKEWESSIEPKAIIRCAVPQNENELKLLNQIISLVVEIYDGFTQDLVQQSPNLFITNDILKRTTNLRQQELNKIKKFMKETELELAKEKKLELEKAKRRQLKASGQQEKVDQKMKEKRERRLKNKQRTRFQ
What are the official names of this protein?
UPF0674 endoplasmic reticulum membrane protein YNR021W.
What is the protein family that this protein belongs to?
Belongs to the UPF0674 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TRM56_HALWD
Sequence: MKRSCENDVSVLRYGHRPGRDDRMTTHVGLTARALGADQVIFPDNATQSAETVSDIVSRFGGPFDVERTDGLNATIREWSGTVIHLTMYGERVQDVTEVIRETCLHHQPLLIIIGGEKVPSDVYEWADWNIAVTNQPHSEVAGLAVFLDRLFMGQELEQEWAGAEHVVVPQACGKRVVDAELTTEADEMNAEK
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS1_LISMO
Sequence: MRKPIIAGNWKMNKTAAKAGQFAEDVKNNVPSSDAVESVVAAPALFLQELVRLTEGTDLRVSAQNCYFEDEGAFTGEISPFALADLGVSYVIIGHSERREYFHETDEDINKKAHAIFKHGMTPIICCGETLDQREAGQTDTWVRGQIRAALAGLTEEQVIKSVIAYEPIWAIGTGKSSTSADANETCAVIRAEVADAVSQKAADAVRIQYGGSVKPENIADYLAESDIDGALVGGASLEPASFLALLEAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase 1, TIM 1, TPI 1, Triose-phosphate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_SYNAS
Sequence: MKWGLLGGTFDPIHMGHLRCAEEIREIFDLNRIIFIPASHPPHKLDAAVTSFYHREQMVRLAIEGNPSFSFSDVENLRAGKSYSIETVEYFLNKYLKSIEIYFILGQDAFQAIQTWKDWQKLLLLCNFSVLTRPGYESMGLSGILPEEFARQFIYDEAADGYRGPSGHLIYFRQVTFLDISSSDIRARVKNGKSITYLTPDSVRHYIKKNKLYSTE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ABCX_STRMU
Sequence: MALISMKNVTLKKQGKILLNNLNWKVKKGENWVILGLNGSGKTTLLKLIMAEYWSTQGQVEILNTRFGQGDIPNMRTKIGVVGSFIAERLPANMLAEKIVLTGKYKSSILYKEYDETELNEARQMLTVIGGKHLLGRIYSSLSQGEKQLLLIARSLMEDPEIIILDEATSGLDLFAREKLLTQVEKITELPHAPTILYVTHHAEEITDKMSHILLLRRGKIVAQGPKKDIITPQVLENFYESPVNIISIDDKRFFIKPQV
What are the official names of this protein?
Putative ABC transporter ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: PCY2_HUMAN
Sequence: MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHFKVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARNQKKEAKELAFLEAARQQAAQPLGERDGDF
What is the function of this protein?
Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway (PubMed:9083101, PubMed:31637422).  Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis (PubMed:9083101).
What are the official names of this protein?
Ethanolamine-phosphate cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase, Phosphorylethanolamine transferase.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
Protein: RSMH_HAES1
Sequence: MQDTFSSPEHFTVLLREAVGGLALKENGIYIDGTFGRGGHSRFILSQLSKKGQLIAIDRDPQAIQVAQNIQDSRFRIVHDSFSAIPDICEKLGLTGKIDGILLDLGVSSPQLDNAERGFSFMKDGPLDMRMDTTQGLSATEWLRLVSEQDLAWVLKTFGEERFAKRIAQAIVGYNKSAVQSGAEPLNRTLQLAELIAQSVPFKDKYKHPATRSFQAIRIFINSELDELEKVLNGALNVLAPQGRLSIISFHSLEDRMVKHFIRKQSKGDDLPKGLPLREEQIQHNQKLKPVGKAIMPTEQEMAANVRSRSAVLRIAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_THEON
Sequence: MKVKVFNLEGEPVEEIELPNVFATPFRPDLIRRAVIASWTHRIQPQGRDPLAGKRRVTENIGKGHGMARVERIKTSPRFAAFVPFARGGRRTHPPKVEKIIWEDINKKERRLAIMSAIAATANYDLVRARGHIVDNVPQVPLVVVNDLEKVFKTAQTREIFKKLGVWDDIERAKKNTKIRAGKGKMRGRRYKKAKGPLIVVAKNEGIVQGARNHPGVDVVTVENLGVELLAPGTHPGRLTIWTKGAIERLREIYG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS20_STRZT
Sequence: MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELFRAASSAIDKAETKGLIHKNKASRDKARLSTKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YCF12_SYNJB
Sequence: MFGQYEVFVQLALLALIVLAGPAVILLLYLRGADM
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: Y2609_MYCBO
Sequence: MRWARQAVAVNGMPVDDGALPGLQRIGLVRSVRAPQFDGITFHEVLCKSALNKVPNAAALPFRYTVNGYRGCSHACRYCFARPTHEYLDFNPGTDFDTQVVVKTNVAAVLRHELRRPSWRRETVALGTNTDPYQRAEGRYALMPGIIGALAASGTPLSILTKGTLLRRDLPLIAEAAQQVPVSVAVSLAVGDPELHRDVESGTPTPQARLALITAIRAAGLDCHVMVAPVLPQLTDSGEHLDQLLGQIAAAGATGVTVFGLHLRGSTRGWFMCWLARAHPELVSRYRELYRRGPYLPPSYREMLRERVAPLIAKYRLAGDHRPAPPETEAALVPVQATLF
What are the official names of this protein?
Uncharacterized protein Mb2609c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVSE_BACC3
Sequence: MIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISSSTLQW
What is the function of this protein?
Component in a DNA repair pathway.  Removal of UV LIGHT damaged nucleotides.  Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion (By similarity).
What are the official names of this protein?
UV DNA damage endonuclease, UV-endonuclease, UVED.
What is the protein family that this protein belongs to?
Belongs to the uve1/UvsE family.
Protein: RL17_BURO0
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMSNSLIEHEVIKTTLPKAKELRKVVEPLITLGKKPSLANRRLAFNRLRDRDSVAKLFDVLGPRFANRPGGYLRVLKFGFRVGDNAPMALVELLDRPEVDETENVQEAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DDT4L_ONCMY
Sequence: MVYTPALVLGHGIPIVSEEDNIVELMRKFLCQITSSDNKYVRRGSIESSEFIKEINSSLDSETAPDCEERILHQDMTRQIVRCLSEAKESSLRCRILLLPRTLTANVALDVVRSSAGEPCGLRGAFIQVYLETQLGQQLQMLGTITPDPTVTPTFELSVVFKLDKDCWPLLKHIFVTDKVLKLRPQYRLVKKKLYSSASPVIHEFC
What is the function of this protein?
Inhibits cell growth by regulating the TOR signaling pathway upstream of the tsc1-tsc2 complex and downstream of akt1.
What are the official names of this protein?
DNA damage-inducible transcript 4-like protein.
What is the protein family that this protein belongs to?
Belongs to the DDIT4 family.
What are the subcellular locations of this protein?
Cytoplasm.