PharMolix/UniProtQA huggingface dataset:
Protein: PXPA_SALAR
Sequence: MKIDLNADLGEGFASDSELLTLVSSANIACGFHAGDAQTMLTCVREALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRHVKPHGMLYNQAAKDPRLAQAIAKAVHDYDSSLILVGLAGSELIRAGERYRLATRQEVFADRGYQADGSLVPRTQPGALILDEGQALAQTLGMVQAGRVKSVTGVWTNVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVSF
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SPRY3_PONAB
Sequence: MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFEPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAARNVRNVMYLHQEGEEEEEEEEEEEDGEEIEPEHEGRKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG
What are the official names of this protein?
SPRY domain-containing protein 3.
Protein: ISPG_BRADU
Sequence: MNKLENTIDSDIAGPAPRHRTTQVKVGDVAVGGGAPIVVQSMTNTDTADIDGTIAQVAALARAGSEMVRITVDREEAAAAVPHIRDGLAKRGITTPLIGDFHYIGHKLLAAYPACAEALAKYRINPGNVGFKDKRDTQFADIIEIANKNSKPVRIGANWGSLDQELLTKLMDENAASANPRDVRAVTREAMVQSALLSAARAEELGMPKDRIILSAKVSAVQDLIAVYQDLASRSDYAIHLGLTEAGMGSKGIVASSAALGILLQQGIGDTIRISLTPEPGGDRTREVQVGQELLQTMGFRTFVPLVAACPGCGRTTSTTFQELARSIQDFIRDEMPAWKTKYPGVEELNVAVMGCIVNGPGESKHANIGISLPGTGEAPAAPVFVDGKKFRTLRGPTISDDFKALVIDYIDQRYGQGAKVPVTAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GCSH_MYCBO
Sequence: MSDIPSDLHYTAEHEWIRRSGDDTVRVGITDYAQSALGDVVFVQLPVIGTAVTAGETFGEVESTKSVSDLYAPISGKVSAVNSDLDGTPQLVNSDPYGAGWLLDIQVDSSDVAALESALTTLLDAEAYRGTLTE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PUR1_MOUSE
Sequence: MELEELGIREECGVFGCIASGDWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSAVPKFRVHKGMGLVNHVFTEDNLKKLYDSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRQGIGLSTSSDSEMITQLLAYTPPQEKDDAPDWVARIKNLMKEAPAAYSLVIMHRDFIYAVRDPYGNRPLCIGRLMPVSDVNDKEKKSSETEGWVVSSESCSFLSIGARYCHEVKPGEIVEISRHGIRTLDIIPRSNGDPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVEADLVSTVPESATPAALGYATKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLIDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDCLAEYLGANSVVYLSVEGLVSSVQQEIKFKKQKVKKHDIAIQENGNGLEYFEKTGHCTACLTGQYPVELEW
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: PPI_LOTGI
Sequence: MNSLVLPLCLLALFGFSQGELLVTKKVYFDIKIGNEPIGRIVMGLFGNVVPRTTENFYQLCTGQNGYGYTGSKFHRVIPKFMIQGGDFTKGDGTGGKSIYGAKFADENFQLEHYGAGWLSMANAGQDANESQFFVTTVKCPWLDGRHVVFGKVLEGMDIVKHIEQMPTDSTDRPIEDVVISESGAIELDTPFAVDKTGVGADEEEE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase, PPIase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEF_RICAH
Sequence: MPLSTSLLGKTSTYKDSYDATLLFKIPRINNRNALGINSNNLPFYGVDIWNTYELSCINKKGKPWVGVGTFYIPTDSENIVESKSFKLYLNSFNNFVVESVEELERIILQDLSNVTHAKVTGRIFPINTKIAFGVPSGKNIDALDIVCNNYGPPDNSLVEYEEVLVEEEINSNLLKSNCLVTGQPDWGSIVIKYKGKKLKHDSFLKYLISFRNYHEFAEQCAERIFTDIKNAIKPDFLSLYIVYTRRGGIDICPYRSTDKSYSLPSDKRLIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_PSEAE
Sequence: MYEWLNALPKAELHLHLEGTLEPELLFALAERNRIALPWNDVETLRKAYAFNNLQEFLDLYYAGADVLRTEQDFYDLTWAYLQKCKAQNVVHVEPFFDPQTHTDRGIPFEVVLAGIRAALRDGEKLLGIRHGLILSFLRHLSEEQAQKTLDQALPFRDAFIAVGLDSSEVGHPPSKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLLKVERIDHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCVFDDMSQHTILDMLERGVKVTVNSDDPAYFGGYVTENFHALQQSLGMTEEQARRLAQNSLDARLVK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: RL18E_HALSA
Sequence: MSKTSPRLSSLIAELKSVARDSGADVWHDVADRLEKPRSTHAEVNLSRIERYASEDETVIVPGKVLGSGALRKSVTVAAVDFSSSAATKIEHADGEAVHLEQAVEQNPDGTDVRVIR
What are the official names of this protein?
50S ribosomal protein L18e, HeL18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: DEOC_ENTFA
Sequence: MELNRMIDHTILKPEATEAAVQKIIDEAKEYNFFSVCINPCWVAFASEQLADTDVAVCTVIGFPLGANTPEVKAYEAADAIKNGANEVDMVINIGALKSQQYDYVRQDIQGVVDAAKGKALVKVIIETALLTDEEKVKACELAKEAGADFVKTSTGFSTGGAKVADIRLMRETVGPDMGVKASGGVHNAEEALAMIEAGATRIGASTGVAIVSGATGEGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT2_ARATH
Sequence: MFAVENGLQGDPRLKAISDAIRVIPHFPKTGIMFQDITTLLLDPVAFKHVVDIFVDRYKHMNISLVAGVEARGFIFGPPIALAIGAKFVPLRKPGKLPGRVISEEYELEYGRDCLEMSVEAVKSEERALIIDDLVATGGTLSASINLLERAGAEVVECACVVGLPKFKGQCKLKGKPLYVLVEPNQFDELTL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.  May contribute to the recycling of adenine into adenylate nucleotides and the inactivation of cytokinins by phosphoribosylation.  Possesses low activity toward adenine and cytokinins.
What are the official names of this protein?
Adenine phosphoribosyltransferase 2, APRT 2, AtAPT2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP78_YEAST
Sequence: MLRQATKAPIQKYLQRTQLLRRSTPRIYTIVQCKRSICSFNARPRVANKLLSDIKTNALNEVAISTCALKSSYGLPNFKRTYVQMRMDPNQQPEKPALEQFGTNLTKLARDGKLDPVIGRDEEIARAIQILSRRTKNNPCLIGRAGVGKTALIDGLAQRIVAGEVPDSLKDKDLVALDLGSLIAGAKYRGEFEERLKKVLEEIDKANGKVIVFIDEVHMLLGLGKTDGSMDASNILKPKLARGLRCISATTLDEFKIIEKDPALSRRFQPILLNEPSVSDTISILRGLKERYEVHHGVRITDTALVSAAVLSNRYITDRFLPDKAIDLVDEACAVLRLQHESKPDEIQKLDRAIMKIQIELESLKKETDPVSVERREALEKDLEMKNDELNRLTKIWDAERAEIESIKNAKANLEQARIELEKCQREGDYTKASELRYSRIPDLEKKVALSEKSKDGDKVNLLHDSVTSDDISKVVAKMTGIPTETVMKGDKDRLLYMENSLKERVVGQDEAIAAISDAVRLQRAGLTSEKRPIASFMFLGPTGTGKTELTKALAEFLFDDESNVIRFDMSEFQEKHTVSRLIGAPPGYVLSESGGQLTEAVRRKPYAVVLFDEFEKAHPDVSKLLLQVLDEGKLTDSLGHHVDFRNTIIVMTSNIGQDILLNDTKLGDDGKIDTATKNKVIEAMKRSYPPEFINRIDDILVFNRLSKKVLRSIVDIRIAEIQDRLAEKRMKIDLTDEAKDWLTDKGYDQLYGARPLNRLIHRQILNSMATFLLKGQIRNGETVRVVVKDTKLVVLPNHEEGEVVEEEAEK
What is the function of this protein?
Required, in concert with mitochondrial Hsp70 (SSC1), for the dissociation, resolubilization and refolding of aggregates of damaged proteins in the mitochondrial matrix after heat stress.  May extract proteins from aggregates by unfolding and threading them in an ATP-dependent process through the axial channel of the protein hexamer, after which they can be refolded by the Hsp70 chaperone system.  Required for resumption of mitochondrial respiratory function, DNA synthesis and morphology after heat stress.  Its main role may be maintaining the molecular chaperone SSC1 in a soluble and functional state.  Also required for the efficient degradation of proteins by matrix protease PIM1, independent on its protein remodeling activity.
What are the official names of this protein?
Heat shock protein 78, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NSRR_ECOBW
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: YMDB_ECOL6
Sequence: MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQQGDE
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate.  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: YR554_MIMIV
Sequence: MGNTTSEIQTQNVEAQPLISTEEQLSVDNPSIQSDQSVDTVENTVNDTVNDTVENTVNDTVQSIINKKYVHPVIDLINSNQSENEIIEVLKSFVGTNVVGTNENGQTIYDCVDQVELFGPAMQVFCHCACYGKKDVTDWILKNYVPLQVSYGDNFTFFETQKYKHFDISDMLVKHESFVPSYEVMQNLLSRSKYDLLEHCLNNPNLEKSHIDHYNLFIQYLSNKQYSNINELLVSLKKDSNTPIVSGNESETQPLQVTEIVNVNDNVTLDEISYSEIVTDTLPQNVESGIQLESTTEVKPESTTEVKPESTSEVQPESTTEFQPESTTVVEPESTTKVEPESTTEFQPESTTEVEPESTTEPQVESTTEFQPESSTEPQVESTVEVQAESMNESSYFQYNKPTYDI
What are the official names of this protein?
Uncharacterized protein R554.
Protein: TAAR8_HUMAN
Sequence: MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 8, TaR-8, Trace amine receptor 8, G-protein coupled receptor 102, Trace amine receptor 5, TaR-5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRDA_STRPQ
Sequence: MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVTKTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVVGLSPTETETILKVIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTKPLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGIGGDYIKPTALANVHAFYKRLKPSIHIIGTGGIKTGRDAFEHILCGASMVQIGTALHQEGPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEMO_STAAS
Sequence: MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQATKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDLDPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKADTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANIEGAQKIYDLFKPILEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPLSKMAVITE
What are the official names of this protein?
Efem/EfeO family lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PPIA_SAGOE
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFICTVKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: PGKA_TRYBB
Sequence: MSTAPNAKNNISLKKSVGDVWPLTAKRVLMRVDFNVPMQNGHITNDYRIRAAIPTIRRVIDQGGICILLSHLGRPRGVSMVAGVRDIRRRYHEAQFHDNKGKTAFFSVLPGEEKVKILAKSSAREEATHISPEVKSGKTMLFARLPEDEKKSLLMQYLNENKDSALPQMSVSAGYEEQYSLRPVAVRLAELLGQHVYFAHDCLDARVEVSRLKRGNVMLLENVRFYSEENGENAEEREAMAKILASYGDVYISDAFGAAHRDSATMTGIPKILGHGAAGYLMEKEISYFAKVLGNPPRPLEAIVGGAKVSEKIQLLDNMKQRIDYLLIGGAMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTQKRGLMSIIGGGESAGAAEAARISHVSTGGGASLELLEGKTLPGVAVLDDKE
What are the official names of this protein?
Phosphoglycerate kinase A, PGK A allele 2.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
Protein: HIS2_RHOJR
Sequence: MKQWVLVKTFESLFAELTERAATRPEGSGTVAALDAGVHSQGKKILEEAGEVWIAAEHESDEALAEEISQLLYWTQVLMVGKGLKLEDVYRHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y896_STAAW
Sequence: MILGLALIPSKSFQEAVDSYRKRYDKQYSRIKPHVTIKAPFEIEDGDLDSVIEQVRARINGIPAVEVHATKASSFKPTNNVIYFKVAKTDDLEELFNRFNGEDFYGEAEHVFVPHFTIAQGLSSQEFEDIFGQVALAGVDHKEIIDELTLLRFDDDEDKWKVIETFKLA
What are the official names of this protein?
Putative phosphoesterase MW0896.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: ICP27_SUHVK
Sequence: MEDSGNSSGSEASRSGSEERRPVRERLGSRPPERRPVRARLGAIRRRRGGRGGRAARQALRQRRRQQQQQQRQQQHQRRRQEADRPDGGPDAPPDRLSESARAAVSATHARVGATRVNELFASARHDLSRPVFNDGFRAAGSSPWAAVLEFGAEQFTPDGRRVTWETLMFHGADLHRLFEVRPHATEAARVLREMVLLNEGLTESLASADETLTWVKLILTKGLTLRTLDPIVATAGAVLQNLRLKLGPFLRCYLRDTPVDELVRRRRLRDVRCIVTYTLVMLARIARVVERGSSCVLPEDLGDSPVPLEEYVPGACLGGIMDALDSHKTGCDAPTCRLTCSYTLVPVYMHGKYFYCNHLF
What is the function of this protein?
Multifunctional regulator of the expression of viral genes that mediates nuclear export of viral intronless mRNAs.  This immediate early (EI) protein promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP (By similarity).
What are the official names of this protein?
mRNA export factor ICP27 homolog, Protein UL54.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: LPXB_ACIAD
Sequence: MYGTCHLSTHKLKIGIVVGEVSGDTLGVQLMRSFREQGIDAEFEGIGGPQMIAEGFNSFYPMETLSVMGIVEVLKDIKKLFAVRDGLVQRWREHPVDVFVGIDAPDFNLRLSKSLKEKNLPIRTVQYVSPSVWAWRQGRVKGIKATIDLVLCLFPFEKNFYEQHSVRAAFVGHPLAKLLPLNNSLVEAKQALGLNPEKTYIALLPGSRKGEVERLLPMLLGSAEILLKKYPDVEYLIPAISDVRKKQIQDGIQSIAPQYAQKLHVLENQDQESKIGRQVMNASDIVALASGTATLEAMLLHRPMVSFYKLNTLTYIIAKLLVKIQYYSLPNIIAGKKVIEELIQKDANPERLAHEIEKLMNNETAKIQMMQHFSMHKQLISGNTEDPVQAIMTLIQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RS10_HAEI8
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RBSA_VIBPA
Sequence: MTQAILQLSEIEKAFPGVKALDKASLNVYPGRVMALMGENGAGKSTLMKVLTGIYHMDAGSIQYQGQPAAFKGPRDSQEAGISIIHQELNLIPELTIAENIFLGREFTGSMGRIQWSKMYAEADRLLQRLNVKHSSKTLLGDLSLGEQQMVEIAKALSFESKVIIMDEPTDALTDTETESLFKVINELREQGCGIVYISHRLKEIFEICDDITVLRDGKFIGECRVADTDEDGLIEMMVGRKLEEQYPRIDVKHGETCLEVVGLTGSGVHDVSFTLKRGEILGISGLMGAGRTELMKVIYGALPSEHGVINLDNKTINPVSPQDGLANGIAYISEDRKGDGLVLGLSVKENMSLCALDKLTKGVQIQHGEEVIAVEDFIKLFNIKTPTRDQIIGNLSGGNQQKVAIAKGLMTKPKVLILDEPTRGVDVGAKKEIYQLINKFKADGMSIILVSSEMPEVLGMSDRILVMHEGRITGEFDAKDADQEKLLACAVGKKINEEAA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZSC10_HUMAN
Sequence: MGPRASLSRLRELCGHWLRPALHTKKQILELLVLEQFLSVLPPHLLGRLQGQPLRDGEEVVLLLEGIHREPSHAGPLDFSCNAGKSCPRADVTLEEKGCASQVPSHSPKKELPAEEPSVLGPSDEPPRPQPRAAQPAEPGQWRLPPSSKQPLSPGPQKTFQALQESSPQGPSPWPEESSRDQELAAVLECLTFEDVPENKAWPAHPLGFGSRTPDKEEFKQEEPKGAAWPTPILAESQADSPGVPGEPCAQSLGRGAAASGPGEDGSLLGSSEILEVKVAEGVPEPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGRSFLCLCCGKSFGRSSILKLHMRTHTDERPHACHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPPCAPESKAEAPPLTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEGSGSRRRDSDRRPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQLVSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFGQTQDLARHQRSHTGEKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRRHLATHAEPGQEQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRHLRTHARETLY
What is the function of this protein?
Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency.  Can both activate and /or repress expression of target genes, depending on the context.  Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence.  Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 10, Zinc finger protein 206.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPL_STAAC
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGVGLVEALPIIGVVIAFMTFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_LISMH
Sequence: MSKIPVIVIVGPTAVGKTSLSIELAKRLDGEIISGDSMQVYRGLDIGTAKITPEEMGGIKHYLIDVTDPSVPFTAAKFQSETRKAIETIHQAGKLPIIVGGTGLYIQSVFYDYDFGNASEDKAYRAKLEQLDKVILWQMLEQQDPESARQIHENNKRRVIRALEVMHLTGKPFSEYQVHNVLNDTYKPLFLGLDLDRELLYERINQRVNLMFEQGLITEAKKLYEQHLVDVPAVRGIGYKELFPYFERKSSLEEAKELIQKNSRHFAKRQLTWFRNRMDIDWIQAGVSSTESEALNKATTFLTAK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.