PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_HAES1
Sequence: MNLHEYQSKKLFADYGLPVTKGYVCENVEQALSAIEKLSGSQWIAKCQIHAGGRGKAGGVKVVKSAQEVRSFFTKFLGQRLVTVQTNEQGQPIHQIYLEPCAEIQKELYLSAIIDRSSQRIVFMASSEGGMDIEEVAEKTPHLLHRVTIDPLVGAMPYQGRELAFKLGLSGKQIQQFSQIFCQLAKLFVEKDLSLLEINPLVILKNDELFCLDAKVVVDDNALYRHPDLFSMRDLTQEDPREAEAEKWNLNYVALDGNIGCMVNGAGLAMGTMDIIKLHGGRPANFLDVGGGATKERVMEAFKIILTDSAVKAVLVNIFGGIVRCDLIAKGIVSAINEIGVSVPVIVRLEGTNADLGCEILAQSNLNLIAVNSLTEAAEQAVNAAKESE
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DHAS_NEIMB
Sequence: MKVGFVGWRGMVGSVLMQRMKEENDFAHIPEAFFFTTSNVGGAAPDFGQAAKTLLDANNVAELAKMDIIVTCQGGDYTKSVFQALRDSGWNGYWIDAASSLRMKDDAIIVLDPVNRDVLDNGLKNGVKNYIGGNCTVSLMLMALGGLFQNDLVEWATSMTYQAASGAGAKNMRELISGMGAVHAQVADALADPAGSILDIDRKVSDFLRSEDYPKANFGVPLAGSLIPWIDVDLGNGQSKEEWKGGVETNKILGRSDNPTVIDGLCVRVGAMRCHSQAITLKLKKDLPVSEIETILAGANDWVKVIPNEKEASIHELTPAKVTGTLSVPVGRIRKLGMGGEYISAFTVGDQLLWGAAEPLRRVLRIVLGSL
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: RPOC2_MESVI
Sequence: MGRMKKIFFNQKSDLNSMKLFFCNRIMNKGEIRRIIAWFLFNHGTSRTAHMVDRLKILGFYHATKAGISLSIDDLSIPPTKKWLLEDAEQEIAKTQKNYSIGKITAVERFQKVIDTWHSTSETLKNEVVQYFEQTNPLNPVYMMAFSGARGNLSQVSQLVGMRGLMSDPQGQIIDLPIRSNFREGLTVTEYVISCYGARKGLVDTALRTADSGYLTRRLVDVAQDMIIRETDCGTKSGILLGPVKDEQKVVFSLQERLIGRVLAENIYSPKQKQYIAKKNQDISASLSDKICEIKRTNILVRSPLTCKSIRSVCQLCYGWSLAHGNLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGNIAKQIRSSIDGKIIYSLTNTIPMRTRHGEIALITQSNINICIQGKNKEFNIEVPINTILLVNNGSMVRAKQLIAEVSAPVNAQSVEIASKYVASDFSGEIHFENLLLQEKKSAYGHKMNRAGQYGGLLWILSGQVYKFSLDVPLMFDTADYIHNGSCMAEHNIISQYGGILQTSENNLTIDNSNSYLYVLNSSMTIINAYLSHIKNARSEAYILTDDLNQKFFMQVESNNVIKNNQIIAKFVTKTYLTNTGGILKYSSEIEVDEYDIVTQSYPVRKGGIIMWIPEETHLINKDASLLMVRDCEYVEAGTQIIKDLICHSSGLAQVSQTNDILREVVIKPGKIYRPIDFSQVLDKHQTLIQAGEEICDGIIAEELVYLENVNLSSGSALLIRPVVQFLIPNSTELKKLEAQYQLKQNISIQPSIHICYKDGQRIHAWQSMEIAKIFLRLEIDSHLHKLNVTLNLIENKLLQIKMFEYLMIDLNQIIDFQSYQNVTRLVRKFNNYIIPGTILAKTEIIAKDHGEVRQSNKNFEEQKSFLIMNEHDQMTLFVKNAYEFFQLGDLVHKGKEIVPGILAPQSGQVIQLQANRVTLRLARPYLVSSEAVLYVDDGDFVKSGDTLVMLIFEQSKTGDIVQGLPRIEELLEARRTKGLKPLPNNLHDLLQSFFDEATEKYGIQKAAKKSFEKLQLFLVNEVQSVYKAQGVHISDKHIEVIVRQMTSKVMIEEGGDTTLLPGELIELHRIENMNRNVSVHAKYKPIVLGITKASLNTESFISAASFQETTRVLTKAAIEGKTDWLRGLKENVIIGRLIPAGTGFNVHDKMYSRDLSLSNSYNLAYSSNSQHKRIEQKNAEYNFEDIIFD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS15_MAGMM
Sequence: MSITAERKQELIAEYATKENDTGSPEVQVAILTERINNLTDHLRGHNKDHHSRRGLLKMVGLRRRLLSYVQKEDRSRYQDLIKRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SLX1_ASPFC
Sequence: MDDTQIEHPRPIPIFYCCYLLRSTVRHASLYIGSTPNPARRLIQHNGVVKGGARRTAAEKLRPWEMVLVVEGFMSRLAALQFEWAWQNPWYSRHLRSEESSALAEVKHRRMRKAKSEDPEFLDSNCDSAKSRVKGTPKKSKRRHRPPRSLDTYFSDLHRLLRSTYFSHWPLKIRFFSGDIYQSWKAWYDRVDVRLRSPVKVILDGSCPEISAHAGGNDTRFGGVENAKITYAAIRDYIEKAIFLLDDPKDVRCHVCQGQIVPTEELTTVCPQAECHCTCHLLCLSRKFVDAALEPNQIVPKHGICPACEATIEWPLMMKELSFRSRAKQELLEILKRKRRVDRKQGAVTGEVESSSRRTVSVDLDDRFGQHAEDEFLLDEDWWEGLAAESDSDTDLRLKPLSKAAPKLETVIEDSECDDADIL
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCHO_ECOLI
Sequence: MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLPDLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDNGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQTATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDRVDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVEPFDALSNDELRWEP
What are the official names of this protein?
Uncharacterized protein YchO.
What is the protein family that this protein belongs to?
Belongs to the intimin/invasin family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RECG_ARATH
Sequence: MAAVTLSPCSMCCGSRRLRSVIVIQAQRGNWNRIRLSNFFFSKVWNISYRSKHKYSDNLLEQVEKYASARLENQSKLITKVAALMECDNVDDFIDKKSDEQVKKDLVLACKRFPSIILGDSRPVELYSNSKSYGESSSILKTPTDNSFLPTPMHGGWFDPDNLSRTLSSFCPELLQNDDSSDPREDILDDGSSFTSKTATSEVEATSDDVFAAQRFLATSIDSMPGLSKRHSNQLDSCGFHTMKKLLHHFPRTYADLQNAQVDIEDGQYLIFVGKVLSSKGVRASSSFSFLEVIVSCEVSGRDRTPEDLSHNAEDKAGKSIFLHLKKFFRGTRFTWQPFLNSIQEKHKVGDLVCISGKVKSLRAEDHFEMREYNIDVLKDEEESSHRAQGRPYPIYPSKGGLNPKFLSDVISRALRVLPANMDPIPKEITKVFGLPSLNDAYVGIHEPKTLDEADLARKRLIFDEFFYLQLARLYQMLQSLGTKIEKDVLLEKFRKPVLNSVYIEEWSTLTKSFLKALPYSLTPSQLSAVSEIIWDLKRPVPMNRLLQGDVGCGKTVVAFLACMEVIGSGYQAAFMAPTELLAIQHYEQCRDLLENMEGVSSKPTIGLLTGSTPAKQSRMIRQDLQSGAISFIIGTHSLIAEKIEYSALRIAVVDEQQRFGVIQRGKFNSKLYGTSMISKSGSSDSDDTSKADLSMAPHVLAMSATPIPRSLALALYGDISLTQITGMPLGRIPVETHIFEGNETGIKEVYSMMLEDLKSGGRVYVVYPVIDQSEQLPQLRAASAELEIVTKKFPKYNCGLLHGRMKSDDKEEALNKFRSGETQILLSTQVIEIGVDVPDASMMVVMNAERFGIAQLHQLRGRVGRGTRKSKCLLVGSSTNSLKRLNMLGKSSDGFYLANIDLLLRGPGDLLGKKQSGHLPEFPVARLEIDGNMLQEAHIAALNVLGDSHDLEKFPALKAELSMRQPLCLLGD
What is the function of this protein?
Critical role in recombination and DNA repair.
What are the official names of this protein?
ATP-dependent DNA helicase homolog RECG, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CPSF2_MOUSE
Sequence: MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPTEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSAMAQQKAMKSLFGEDEKELGEETEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  Involved in the histone 3' end pre-mRNA processing (By similarity).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EUTJ_ECOLI
Sequence: MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSMVVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPPGTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVTYSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGEEIWPAVKPVYEKMADIVARHIEGQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLYAK
What is the function of this protein?
May protect ethanolamine ammonia-lyase (EAL, eutB-eutC) from inhibition, may function in assembling the bacterial microcompartment and/or in refolding EAL, suggesting it may have chaperone activity.
What are the official names of this protein?
Ethanolamine utilization protein EutJ.
What is the protein family that this protein belongs to?
Belongs to the EutJ family.
Protein: GLYA_RHOP2
Sequence: MSTSAKHTSAPDSFFSASLEQADPEIAAAIKGELGRQRHEVELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGGCEFVDVAENLAIERAKKLFGAGFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAAGGHLTHGATVNMSGKWFKPVHYTVRREDGIIDMDAVAKLAEETRPKLIIAGGSAYSRAWDFKRFREIADSVGAYFMVDMAHFAGLVAGGAHASPVPHAHVCTTTTHKSLRGPRGGLILTNDEALAKKFNSAIFPGLQGGPLMHVIAAKAVAFKEALQPDFKVYAKNVVENAKALAETLRAAGFDLVSGGTDNHLMLVDLRPKGLKGNVSEKALVRAAITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQVGNLIAEVLNAIAQSPDGAAPLVEASVKQRVKELTDRFPIYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM1_STRPJ
Sequence: MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPADLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPVVLDPVACGAGEYRKKVADDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVTGEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVYNIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 1, 4-methyl-5-beta-hydroxyethylthiazole kinase 1, TH kinase 1, Thz kinase 1.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PLSY_CHLL3
Sequence: MMTLLAILAVSYIIGSIPTSIMAGKMLKRIDIRQFGSGNAGGTNAFRVLGWKTGLSVTLIDIAKGVIAAVSVVAFFRMHPIGAYPDINEVALRLLAGMAAVIGHVFTVFAGFKGGKGVSTAAGMLIGIAPVSMLIVIGIFLLTVWLSRYVSVASILAAIAFPLIIAIRKYVFELGGGLDYYIRLFGESFSFHDSLDYHLMIFGLIVALAILYTHRANIRRLISGTENRITFGKSA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNH2_BURP0
Sequence: MATTRKPRGGAGGATQPALDFDAPGEIVCGVDEAGRGPLAGPVVAAAVVLDPARPIVGLDDSKALSAKKRERLFDEIVAYALAYSVASASVEEIDSLNILHATMLAMKRAVEGLSVLPTLAKIDGNRCPMLAIRSEAIVGGDALVPSISAASILAKVTRDRMLVELHQQFPMYGFDAHAGYGTPQHLAALREHGPCEHHRRSFAPVREAFDLIR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_SHIBS
Sequence: MSKSRLTVFSFVRRFLLRLMVVLAVFWAGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHRGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RLMN_STAA2
Sequence: MITAEKKKKNKFLPNFDKQSIYSLRFDEMQNWLVEQGQQKFRAKQIFEWLYQKRVDSIDEMTNLSKDLRQLLKDNFTVTTLTTVVKQESKDGTIKFLFELQDGYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKALDATEERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIYDFADEDIQINFAVSLHAAKDEVRSRLMPINRAYNVEKLIEAIQYYQEKTNRRVTFEYGLFGGVNDQLEHARELAHLIKGLNCHVNLIPVNHVPERNYVKTAKNDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  Confers resistance to some classes of antibiotics.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HVM22_MOUSE
Sequence: EVKLVESGGGLVQPGGSLRLSCATSGFTFSDFYMEWVRQPPGKRLEWIAASRNKANDYTTEYSASVKGRFIVSRDTSQSILYLQMNALRAEDTAIYYCARDYYDYPHWYFDVWGAGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region HPCM6.
Protein: GBRT_HUMAN
Sequence: MGIRGMLRAAVILLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANEAVVQKILDRVLSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTLNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRRVIARYRYQQVVVGNVQDGLINVEDGVSSLPITPAQAPLASPESLGSLTSTSEQAQLATSESLSPLTSLSGQAPLATGESLSDLPSTSEQARHSYGVRFNGFQADDSIIPTEIRNRVEAHGHGVTHDHEDSNESLSSDERHGHGPSGKPMLHHGEKGVQEAGWDLDDNNDKSDCLAIKEQFKCDTNSTWGLNDDELMAHGQEKDSSSESEDSCPPSPGCSFTEGFSFDLFNPDYVPKVDKWSRFLFPLAFGLFNIVYWVYHMY
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit theta, GABA(A) receptor subunit theta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRQ sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: MEP1_VERA1
Sequence: MLFKSLFVAAATAVGVSGHVAREAPRTFGCGTHEPSAEHVGMSKVLAAQEARVLESGNLTARATINVNVYFHVVAASQTVANGYLTDKMVTDQIAVLNRDFAPHDVAFRLAGTDRTVNTGWARDSNEIAMKRALRKGTYKDLNLYTQVSLTDNALGYAYFPTSGATSGSTTFIRDGVSIKAQTVPGGSQAGFNLGKTGTHEVGHWLGLYHTFQGGCTGSGDQVSDTPAQASFSSGCPIGRDSCPGQAGLDPIHNYMDYSDDSCYEEFTPGQDARIHSFWTTYRA
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloprotease VDBG_01143.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSPA_CHLFF
Sequence: MSNRSRSTLLTISFFVLIDWVTKLAVLLYRGNLPNANPILYQYSWGKLFFCICPTFNEGAAFGLFSKYKYFLLLIRIVIILGILAFLFLRKKKTSATTRFSLILLCSGAIGNVGDIFFYNHVIDFISIGYNRWSFPTFNFADIFISLGTLIFVYKLYFPTKQKIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYTS_ENTFA
Sequence: MVELFILMMERVGLIILLAFLLVNVPYFKRVLLSREKMSSKVQLILIFGLFAIISNFTGIEIAKNQIVPNNLLTYLSSNASIANTRTLVIGVSGLVGGPIVGSAVGLIAGFHRVIQGGGHSFFYVPASLIVGLIAGFLGSRMAKQTVFPSAGFSAIVGACMEMIQMIFIFFFSGDLSDGATLVRFIALPMILLNSVGTFIFMSILTTTLKQEEQAKAVQTHDVLELAAETLPYFREGLNKNSSKKVAEIIKHYTKVSAISMTNSHQILAHVGAGSDHHIPELEVITELSREVLRTGRMTIAHAKEEVGCSDPNCPLQAAIVIPLFSHQQIVGTLKMYFTDPAQLTHVEEQLAEGLGTIFSSQIELGEAEVQSKLLKEAEIKSLQAQVNPHFFFNAINTISALMRKDSEKARKLLLQLSKYFRGNLQGAVQTTIPVSQELEQVKAYLSLEQARFPNRYQVTFDVEEAVASEKVPPYAIQVLVENTIKHAFGSRKENNQVRVVVKAKQHKLHVDVYDNGQGIPEERRLLLGKTTVTSEKGTGTALENLSRRMANLYGSEGCFLIENLETGGSHVHLEIPMEQEELDARINR
What is the function of this protein?
Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensor protein LytS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSRP_BURO0
Sequence: MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFVDSLDKAYATVEKINEAAVHDGRRAIVFTTLVDSESNDIVKRSNALVLDMFQRFVEPLEQELELKSSHAMGRGHQNADTEEYKTRIEAINFSLAHDDGQSNRNLSEADVILVGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPSALAPYSEKLFGLSIDPQRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGIKWLSSTHKSIEEIATTILQEIRLDRQSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RL34_AERHH
Sequence: MKRTFQPSNLKRKRSHGFRARMATANGRKVLAARRAKGRARLVV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: OPGH_PSEA8
Sequence: MNNPSTTKAPLADYLAHLPLAEEERERLGESASFSELHARLAGAEGAAADAGGDPALASVRARLQLGTPELDDAEMFGVDAQGRTFLKISPPIRRTKVIPEPWRTNILVRGWRRLTGRSNPPKPKRALPRARWQRVGSLRRFILLLLMLAQTSVATYYMKGILPYQGWAFVDLEELAQQSLLDTVQQVLPYVIQFGILALFAILFCWVSAGFWTALMGFWELLTGRDRYRISGSSAGSEPIAADARTAIVMPICNEDVPRVFAGLRATVESMAATGEMERFDFFVLSDTNDPDIAVAEQQAWLELCRETKGFGKIFYRRRRRRVKRKSGNIDDFCRRWGGDYRYMVVMDADSVMSGDCLAKLVRLMEANPEAGIIQTAPKASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMQPFIDHCALAPLPGKGSFAGAILSHDFVEAALMRRAGWGVWIAYDLDGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVHQLMEPQYFLEPRQLFPIWPQWHPEKAIALFSTTLTLLFLPKLLSVMLIWAKGAKGFGGVIRVTLSMLLEMFFSVLLAPVRMLFHTRFVLAAFLGWSVQWNSPQRDDDATPWSEAIRRHGMQTLLGIAWTLLVAWLNPRFLWWLSPIVGSLILSIPVSVISSRVKLGLRARDEKLFLIPEEYDTPRELRATDEYTYENRWHALKDGFLKAAVDPLLNALACAMGTARHNRAQAIETVRGERIGKAIDKGPEQLDGATRLALLSDPVALSRLHTRVWEEDRDDWLGRWRKAEADDPHAASVPLAQVVPGDAGLLPAAQS
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS21_CHLAB
Sequence: MPSVKVRVGEPVDRALRILKKKVDKEGILKAAKAHRFYDKPSVKKRAKSKAAAKYRSR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL4A_YEAST
Sequence: MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLKHD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uL4 participates in the regulation of the accumulation of its own mRNA (PubMed:2065661).
What are the official names of this protein?
60S ribosomal protein L4-A, L2, Large ribosomal subunit protein uL4-A, RP2, YL2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.