PharMolix/UniProtQA huggingface dataset:
Protein: MSD9_AMABI
Sequence: MSDINAIRAPILMLAILPCVGDDIEVLR
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:18025465).
What are the official names of this protein?
MSDIN-like toxin proprotein 8.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: PSBT_ANACO
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AEP1_YEAS7
Sequence: MITTVQEISKWRNLWFIRMQSRKWYPVLKKTPLVADGRKIIKHADKVPHPEEIIHPFYQPTAIEQFTACATEYNPSLLDGKKIAPSLIKHPVSLKTILVDSKLKFDDIRGVNRWLMEFVARRQHQRNIVLTPASKSVRSFHVLHLSSTDIAKLRALENVLSEIENTNDLQSRVESVNNELQNIFDRDSKQTRLFCEDILAYLIKNYGNSTEKLILLINVTEMQLYSRLDQMKAMNIILYHILCKVEANENPPYSPTLVTALENLLAAINNRFFPGRCENSLHPIVIEQLLSYFIKTGNLNESKNFLGHLIKKGILPEATIINRYLEAIDVHFDKSTKIFDIRSKFAFIADLAPIIENYGTIDLFKFLIPMCRHFDELCSLLNIIRKSNNAKRAVDSTLPIFIKKVLTFTKDPMINSGNLSTVFNMVSPIYGQNVPSEFVEKFILSFALQGNYTMMAHMIDTYKIKLSHKYQLQIIRALKNSERNHALKNTGAVGYNKEFKKYFIEKYLNCTEREALRP
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.
What are the official names of this protein?
ATPase expression protein 1, mitochondrial, Nuclear control of ATPase messenger RNA expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the AEP1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: REPA1_BUCBP
Sequence: MLKRKNYVNNISPLFTPPKGDKRRPAFINYALEQAKKIDVARSELNYILKLRDPKTGSIIPRHRQLNEHRAAAMRVIVPAMIYHFNITSDLVQASIEQLADECGLSTVSKSGNKSITRASRLISQFMEPMGFIKCKKKWDKILGCYMPKIIMLTPLFFELIGISKEKLNNAKKQQLGWLNTKLIERGLKPLSFSDAKLVSREKQINKILELRNNFHLLQRKKRYAKKLFKLDEKDIRQKIIKYLVSKYSSSELAQISLQEFKKQVNIEYFYLRNLANEPYLISRR
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.
What are the official names of this protein?
Probable replication-associated protein repA1.
What is the protein family that this protein belongs to?
Belongs to the IncFII RepA family.
Protein: RECX_TREPS
Sequence: MGTRPTDEQYGAVCFACRCYEAECVAVRLLARSETSAQQLGFKLLKRGFEKRVVESVFPVLKRYSWLDDTRFARAWLRNRVDSRPASRAQLLGELKRRGVSHADAEGALDLLFQEQDEETLCLRLLEKLRRRGYGPHTLQRALQRRQFSPSLVRRCLAVETEGA
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_HAHCH
Sequence: MQQRELNYLFLKRIGINTHQEPVVYMRQDCHVCRSEGFNAHSRVRVTTNKRSIIATVHQVTDGWLSHQEAGLSDAAWRLLEAEDGEVAYFSHTKAVDSMSHVRGKLYGASLTQESADEVVKDVAGGLYSDVQLAAFVTACAGSRLNQDEVAALTSAMVKVGQRIDWGTSPIMDKHCVGGLPGNRTTPIVVAIVTACGLRMPKTSSRAITSPAGTADTMETMAPVNLTLAQMKKVVEQEGGCIAWGGSVSLSPADDVLIRIERALDLDSEGQLVASVISKKVAAGSTHVLIDIPIGMTAKVRSPEYAERLASHMRYTGVKLGIQVEAMFTDGAQPVGRGIGPALEARDILAVLRNQAEAPADLRVRALTLAGRLLEIGGVASHGAGVARARETLESGAALHKFMAICEAQGGFREPALAPHCYEATADRVGVVSFVNNRFVAKLAKLAGAPSNSSAGVDFHVKLGQKVRVGEPLFSIYAEAPGELAYALDFLRDHPNEIRIEEESL
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: PEPQ_PECCP
Sequence: MEKLASLYHHHLATLQARAQTVLARHQLDALLIHSGELLTVFLDDHDYPFKVNPQFKAWVPVTQVPNCWLWVDGVNPPKLWFYSPVDYWHNVAPVPESFWTEEIDITVLRNADDIGQLLPSQRERVAYIGYAPQRAQDLGIRADNINPQSVLDYLHYHRAYKTDYELACMREAQKTAVIGHRAAHEAFLSGMSEFDINLAYLTATGHRDIDVPYGNIVALNEHAAVLHYTQLDHHAPSDVRSFLIDAGAEYNGYAADLTRTYSAQSDGAFALLIKDLNQEMLALIDTVQAGVRYTDYHIQMHQRIAKLLKSHQLVRDISEEAMVEQGLTSPFLPHGLGHPLGLQVHDVAGFMQDDRGTHLAAPSQYPYLRCTRVLEPGMVMTIEPGIYFIESLLAPWREGELCQHFDWQKVDALKPFGGIRIEDNIVIHDGRVENMTRDLNLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: MYB64_ARATH
Sequence: MEEQKIQEKSLAHGAAPPLTAVERFLNGQKNEALCFKKQERSIDRPIVKTTRAIEIRNENKENMMFGPRKEKNLAVIGEIVVKGAAKDYTCKDITKKQPYKNIIKGQWTADEDRKLIKLVMQHGERKWAVISEKLEGRAGKQCRERWHNHLRPDIKKDSWSEEEERLLVEAHTRIGNKWAEIAKLIQGRTENSIKNHWNATKRRQNSKRKHKRSKNADSNSDIDDLSPSAKRPRILEDYIKNIENNDKNNGENIMTTSGNNVLSTSNYDQFNSEDSTSSLLDDPYDEELVFLKNIFENHSLENINLSQGTEITQSSSSGFMIENPKPKPNLYNNTFGTHLGAMVTEPANSSHLASDIYLSDLLNGTASSSSSLTFLSSNNNEHAGENELLLPQANSTSERREMDLIEMLSGSTQGSNIWFPLF
What is the function of this protein?
Transcription factor required for female gametophyte fertility (PubMed:23057675, PubMed:24068955).  Acts redundantly with MYB119 to initiate the FG5 transition during female gametophyte development.  The FG5 transition represents the switch between free nuclear divisions and cellularization-differentiation in female gametophyte, and occurs during developmental stage FG5 (PubMed:24068955).
What are the official names of this protein?
Transcription factor MYB64, Myb-related protein 64, AtMYB64, Protein UAS-TAGGED ROOT PATTERNING 10.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCST_ECO57
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHEVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEGGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPKGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PEMK_ECOLX
Sequence: MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQGTRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRTIDMKARGGKRLERVPETIMNEVLGRLSTILT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Probably functions as an endoribonuclease.  Responsible for the stable maintenance of the plasmid during cell division by postsegregational killing of plasmid-less daughter cells.  Neutralized by coexpression with cognate antitoxin PemI.  Both PemI and PemK proteins bind to the promoter region of the pem operon to autoregulate their synthesis.
What are the official names of this protein?
Endoribonuclease PemK, Kid toxin protein, mRNA interferase PemK.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: ODO1_BACCQ
Sequence: MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFEIFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAANGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKEVYTQTLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNQKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEIETITQFTQEQLKSDYAQVPPADTSDATIHVKVPDVVAKGIQSIDTGVELDSLRAINEGLLSWPEGFNVYPKVKKILERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTNETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQALFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGMKPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEIHIVRIEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQELIVSHALDVKYNFRQDKLEIEVFSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: ISPG_MICAN
Sequence: MQTLESTLNPPATASEFDTTIHRRKTRPVQVGSVTIGGGHPVVVQSMINEDTLDIDGSVAGIRRLHEIGCEIVRVTVPSLVHATALAKIREKLLATYQPVPLVADVHHNGMKIALEVAKHVDKVRINPGLYVFEKPKADRSEYSQAEFDEIGEKIAETLKPLVVSLRDQDKAMRIGVNHGSLAERMLFTYGDTPEGMVQSALEFIRICESLDFRNLVVSLKASRVPVMVAAYRLMVKRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEDVLQQVRAATQHLTGLDIAVMGCIVNGPGEMADADYGYVGKQAGYISLYRGREEIKRVPESEGVSELINLIKADGRWVEP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: WSDU1_RAT
Sequence: MVKLIHTLADHGDDVSCCAFSSTLLATCSLDKTIRLYSLSDFAELPHSPLKFHTYAVHCCSFSPSGHVLASCSTDGTTVLWSAHSGHTLTVLEQPGGSPVRVCCFSPDSTYLASGAADGSVVLWNAHSYKLYRCGSVKDSSLVACAFSPDGGLLVTGSSGGDLTVWDDRMRCLHSEKAHDLGITCCSFSSQPLSGGEHGLQLYRLASCGQDCEIKLWVVSFTRVLGFELKYRSTLSGHCAPVLACAFSHDGQMLASGSVDKSVIIYDIGTQSVLHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETPCQAGSVSDQLKHFIEDWSEEDVSKWLRAQGLEDLVDIFRTNNIDGKELLHLTKESLAGDMKIESLGLRSKVLRSIDELRTRMESLSSGIPDEFICPITRELMKDPVIASDGYSYEREAMESWIHKKKRTSPMTNLALPSLVLTPNRTLKMAINRWLETHQK
What are the official names of this protein?
WD repeat, SAM and U-box domain-containing protein 1.
Protein: RS21_BACC4
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLAEARKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: LOG_ORYSJ
Sequence: MAMEAAAERSAGAGAAATAAPESGGGGAGERRSRFRRICVYCGSAKGRKASYQDAAVELGKELVERGIDLVYGGGSIGLMGLVSHAVHDGGRHVIGVIPKSLMPREVTGEPVGEVRAVSGMHERKAEMARFADAFIALPGGYGTLEELLEVITWAQLGIHKKPVGLLNVDGFYDPFLSFIDMAVSEGFIAEDARRIIISAPTARELVLKLEEYVPEYEVGLVWDDQMPHSFAPDLETRITSS
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Controls the shoot meristem activity.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.  Reacts specifically with cytokinin nucleoside 5'-monophosphates, but not with di- or triphosphate.
What are the official names of this protein?
Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG, Protein LONELY GUY.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_AZOVD
Sequence: MSDLSHIRNFSIIAHIDHGKSTLADRFIQICGGLSEREMEAQVLDSMDLERERGITIKAHSVTLHYKAQDGKTYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKMDLPQAEPERVKDEIEHIIGIDAGDAVLCSAKSGMGVPDVLEHLVRVIPPPQGEIEAPLQALIIDSWFDNYLGVVSLVRVKHGRVKKGDKILVKSTGKVHQVDSVGVFTPKHTEMPDLKAGEVGFIIAGIKDIHGAPVGDTLTLSSTPNVDMLPGFQRIKPQVYAGLFPVSSDDFEDFREALQKLTLNDAALQYEPESSDALGFGFRIGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVLLKNGDTICVDNPSKLPDLASIAEMREPIVRANILVPQEHLGNVINLCIEKRGVQRDMQFLSSQVQISYDLPMNEVVLDFFDRLKSVSRGYASLDYSFDRFQVANLVKLDVLINGDKVDALALIVHRDKAHQKGRALTEKMKELIPRQMFDVAIQAAIGGQVVARTTVKALRKNVLAKCYGGDVTRKRKLLEKQKAGKKRMKQVGSVEIPQEAFLAVLKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLYL1_HUMAN
Sequence: MILLNNSHKLLALYKSLARSIPESLKVYGSVYHINHGNPFNMEVLVDSWPEYQMVIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQIQGLQESLGEGIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSKLGSWAETGHPDDEFESETPNFKYAQLDVSYSGLVNDNWKRGKNERSLHYIKRCIEDLPAACMLGPEGVPVSWVTMDPSCEVGMAYSMEKYRRTGNMARVMVRYMKYLRQKNIPFYISVLEENEDSRRFVGQFGFFEASCEWHQWTCYPQNLVPF
What is the function of this protein?
Acyltransferase which transfers an acyl group to the N-terminus of glutamine.  Can use phenylacetyl-CoA as an acyl donor.
What are the official names of this protein?
Glycine N-acyltransferase-like protein 1, Acyl-CoA:glycine N-acyltransferase-like protein 1, Glutamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycine N-acyltransferase family.
Protein: LMOD3_MOUSE
Sequence: MSGHSRNSEQEDTLSEELDEDELLANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFNHKSLVDYMYLQKASRRMLEDERVPVSFVQSEKNTQNQREVGDKGIKNMPQFLKEKLNSEILAKKRESNGSNNVQEAEDDDEDEEEEEEDDEDEEEEEEDEEDDEGEEDEDGEQANREKNDAKEQIHNNPGTYQQLATKTAHEQKDTSETKEKGEKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLRENRSVTTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANTTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQPASGRPLDAQEVPFGSRKEMIKNPPQPPQCKTDPDSFRVVKLKRIQRKSRMPEAREAQEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELE
What is the function of this protein?
Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25774500, PubMed:26035871).  Increases the rate of actin polymerization (By similarity).
What are the official names of this protein?
Leiomodin-3.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton. Note=Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end.
Protein: PSBI_ZYGCR
Sequence: MLTLKLFVYTVIIFFVSLFVFGFLSNDPSRNPGRKE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL30_METJA
Sequence: MAYAVIRIRGRVGVRRDIADTLKMLRLHKVNHCVIIPETETFKGMLQKVKDYVTWGEIDKDTLVKLILKRGRLPGNKKVNPEIIKELTGMDVEELAEKIINGEIKLKETPLKPVFRLHPPRKGFERGGIKKPFSVGGALGYRGEKINELLEKMM
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: THLA_STAAM
Sequence: MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLVEQYGISREEQDTFAVNSQHKAVRAQQNGEFDSEIVPVSIPQRKGEPILVTKDEGVRENVSVEKLSRLRPAFKKDGTVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFAAQLLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
What are the official names of this protein?
Probable acetyl-CoA acyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDC80_MOUSE
Sequence: MKRSSVSTCGAGRLSMQELRTLDLNKPGLYTPQTKERSTFGKLSTHKPTSERKVSIFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTENGYVYSVSMKSLQAPSTKEFLKIFAFLYGFLCPSYELPGTKCEEEVPRIFKALGYPFTLSKSSMYTVGAPHTWPHIVAALVWLIDCIKIDTAMKESSPLFDDGQLWGEETEDGIKHNKLFLEYTKKCYEKFMTGADSFEEEDAELQAKLKDLYKVDASKLESLEAENKALNEQIARLEEEREREPNRLMSLKKLKASLQADVQNYKAYMSNLESHLAVLKQKSNSLDEEIGRVEQECETVKQENTRLQSIVDNQKYSVADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRTQVYAPLKELLNESEEEINKALNKKRHLEDTLEQLNTMKTESKNTVRMLKEEIQKLDDLHQQAVKEAEEKDKKSASELESLEKHKHLLESGVNDGLSEAMDELDAVQREYQLTVKTTTEERRKVENNLQRLLEMVATHVGSLEKHLEEENAKADREYEEFMSEDLLENIREMAEKYKRNAAQLKAPDK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.  Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.
What are the official names of this protein?
Kinetochore protein NDC80 homolog, Kinetochore protein Hec1, Kinetochore-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.
Protein: RSMH_YERPG
Sequence: MVDNNKTVDNNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVGKMMPGDAEIAENPRARSSVLRFAERIGE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_ECOK1
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_LISMH
Sequence: MRVDGRESNALRNIEVTPDYLMHPEGSVLIASGNTKVICSASVETKVPPFMRGEGRGWISAEYSMLPRATNTRNIRESSKGKVTGRTMEIQRLIGRALRAVVDLDALGERTIWLDCDVIQADGGTRTASITGAFIAMVMAIAKLDEAVPFAKFPVKDFLAATSVGVLEEGGTVLDLNYVEDSAAQVDMNIIMTGSGAFVELQGTGEEATFSETELAELIALGKKGISELIEIQKETLGDKVTARIKGE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: HXA5_LEMCA
Sequence: MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAAGATTAPAEPRYSQPATSTHSPPPDPLPCSAVAPSPGSDSHHGGKNSLGNSSGASANAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Also binds to its own promoter.  Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' (By similarity).
What are the official names of this protein?
Homeobox protein Hox-A5.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KIF2B_MACFA
Sequence: MAGQFCLPVSPRLSPLKPLKPHFGDIQVGIYVAIQRSDKRMHLAVVTEINRENSWVTVEWVEKAVKKGKKIDLETILLLNPSLDSAEDPMPVSPLAPAPSSAIGDQSTTTKRVVMIPQKNKTASGDSLDVRVPSKPCLMKQKKSPCLQEIEKVQKQREKRRRLQQEIRARRALDVNTRNPNYEIMHMIEEYRRHLDSSKISVLEPRQEHRICVCVRKRPLNQRETTLKDLDIITVPSDNVVMVHESKQKVDLTRYLENQTFCFDHAFDDKASNELVYQFTAQPLVESIFRKGMATCFAYGQTGSGKTYTMGGDFAGRAQDHSKGIYALVAQDVFLLLRNSIYEKLDLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQEQEVCCVEEVLNLVELGNSCRTSRQTSVNAHSSRSHAVFQIILKSGGKLHGKFSLVDLAGNERGADTTKASRKRQLEGAEINKSLLALKECILALGQNKPHTPFRASKLTQVLRDSFIGRNSSTCMIATISPGMTSCENTLNTLRYANRVKELNADGRPYHRGLYPNGHEASRMLKSHIGNSEMSLQRDEFIKIPCVQSEEQQKEIEDVERATLLGKDTTTSRKGSSQWLENIQERTGGVNHDVDFCIAQSLSILEQKIGVLTEIQKKLKLLRADLHVKSKVE
What is the function of this protein?
Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement during mitosis.  Has microtubule depolymerization activity.  Plays a role in chromosome congression.
What are the official names of this protein?
Kinesin-like protein KIF2B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.