PharMolix/UniProtQA huggingface dataset:
Protein: MTTA_THEAQ
Sequence: MGLPPLLSLPSNSAPRSLGRVETPPEVVDFMVSLAEAPRGGRVLEPACAHGPFLRAFREAHGTAYRFVGVEIDPKALDLPPWAEGILADFLLWEPGEAFDLILGNPPYGIVGEASKYPIHVFKAVKDLYKKAFSTWKGKYNLYGAFLEKAVRLLKPGGVLVFVVPATWLVLEDFALLREFLAREGKTSVYYLGEVFPQKKVSAVVIRFQKSGKGLSLWDTQESESGFTPILWAEYPHWEGEIIRFETEETRKLEISGMPLGDLFHIRFAARSPEFKKHPAVRKEPGPGLVPVLTGRNLKPGWVDYEKNHSGLWMPKERAKELRDFYATPHLVVAHTKGTRVVAAWDERAYPWREEFHLLPKEGVRLDPSSLVQWLNSEAMQKHVRTLYRDFVPHLTLRMLERLPVRREYGFHTSPESARNF
What is the function of this protein?
A gamma subtype methylase that recognizes the double-stranded sequence 5'-TCGA-3', methylates A-4 on both strands and protects the DNA from cleavage by the TaqI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.TaqI, M.TaqI, Adenine-specific methyltransferase TaqI, Modification methylase TaqI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: CUTI1_NEOFI
Sequence: MKFALLSLAAMAVASPVAIDVRQTAIAGDELRTGPCEPITFIFARGSTEPGLLGITTGPGVCNALKLSRPGQVACQGVGPAYIADLASNFLPQGTNQIAIDEAAGLFKLAASKCPNTKIVAGGYSQGAAVMHGAIRNLPSDVQNMIKGVVLFGDTRNKQDGGRIPNFPTDRTKIYCAFGDLVCDGTLIITAAHLSYGDDVPNATSFLLSKV
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).
What are the official names of this protein?
Probable cutinase 1, Cutin hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: UB2SC_XENLA
Sequence: MNSNVENLPPHIIRRVYKEVSTLTSDPPEGIKIIPNEEDITDVQVHIEGPEGTPYAAGIFRMKLILGKDFPAAPPKGYFLTKIFHPNVSNNGEICVNVLKKDWKAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYASRAKLMTEIHAQGSTLRGKDPTDPCSSASATVVSGDGPMAKKHAGDRDKKLAAKKKTDKKRALRRL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme ube2c/ubch10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 S-C, E2 ubiquitin-conjugating enzyme S-C, Ubiquitin carrier protein S-C, Ubiquitin-protein ligase S-C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: LSRA_YERPP
Sequence: MPHTVATPPPLLQVRGISKQFSGVVVLKSIDFTLQPGQVHALLGGNGAGKSTLMKIIAGILPPDTGVIEMNGQPCFNLTPAKAHQLGIYLVPQEPMLFANLSVQENILFRLPKHQADKKKMAQLLKNLGCHLDLSVSAGSLEVADQQLVEIMRGLIRDSHILILDEPTASLTPAETHRLFSQIRMLLQQGVGVVFISHKLPEIRQLADWVSVMRDGGIALSGATADFSTEDMIQAMTPEAQKGALTDSQKLWLELPGNRRAQSHAQSQQPVIHVHDLSGEGFAHISFHVQAGEILGLAGVVGAGRTELAETLYGLRPASTGNVILEEVNITAMKTANRLAAGLVYLPEDRQASGLYLDAPLSWNVCALAHDRQGLWTQPAQEAAVLERYRRALNIKFSHLEQPVRTLSGGNQQKLLIAKCLEANPLLLIIDEPTRGVDVSARSDIYQLIRSIAEQQVAIIFISSDLEEVVQMADRVLVMHQGEINGALSGAAMNVDTIMHMAFGEHRSASEPQGGTASSAENKGASC
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Autoinducer 2 import ATP-binding protein LsrA, AI-2 import ATP-binding protein LsrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL21_JANMA
Sequence: MYAVIKTGGKQYKVVAGEKFKVEQIPADIGSEITLDQVLALGAGETIKFGAPLVAGATVLATVVSHGRHDKVKIFKMRRRKHYQKHQGHRQNYTELQIVSING
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CLPP_WOLPP
Sequence: MTLIPIVVEQTSRGERAYDIYSRLVKERIIFVTGPIEDNMASVIVAQLLFLESENPDKDICMYINSPGGVVTAGLSIYDTMQYINPDVSTLCIGQAASMGSLLLTAGAEGKRYSLPHSRIMIHQPSGGYHGQATDIEIHANEILRVKKKLNQIYEKHTGNSLKKIEEMMERDKFMDPEEAMKTGLIDRVIAERKDMKIENIKVKQKVV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y175_ATV
Sequence: MLQTWAKLAYEANLGIVYGSTLIILLLPLIGSFMPPNLVSSISKLNAFTLLESYLLPVLSNFGIFGGLALGVGSAIAFSVLNSIASSFLNLSFNQQQALTIVVALLVSQFIFGGWATFALFLTSMLGSVPPVPGLAVIMSFITPFIDGLIATLGGLMVVLSILYELSEIGLVTLP
What are the official names of this protein?
Putative transmembrane protein ORF175.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: HIS4_PSET1
Sequence: MIIPALDVLQNQIVRLYQGKYETVQFYPFELGARLKEYADSGAGKLHLVDLEGARDPSKKQWQHIQAATKALNVPYQVGGGIRCEQDVSDWLKAGANQVVIGSMAVEKREQVKAWIEQFGAEHFVIALDVNKTATGWAPATHGWLTESEFGLLELVDFYANLGVIDFLCTDISKDGTMTGPSFALYEDLIKHNSTIKVQASGGVSSLDDIKKLKELGIGGIILGKSLLDGAFSVEEALAVTR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP113_ARATH
Sequence: MLRCWSVTVERSCEGMLLRRRILSLSASSFRNFTSGNNGDAIPFSTFTKPSSSIAPGDFLVREWKDWFKHRDVKQSHQLIDRIFDILRAPSNDGDDRAFYLHLSNLRLRLTEKFVLDVLSHTRYDILCCLKFFDWAARQPGFHHTRATFHAIFKILRGAKLVTLMIDFLDRSVGFESCRHSLRLCDALVVGYAVAGRTDIALQHFGNMRFRGLDLDSFGYHVLLNALVEEKCFDSFDVIFDQISVRGFVCAVTHSILVKKFCKQGKLDEAEDYLRALLPNDPAGCGSGLGILVDALCSKRKFQEATKLLDEIKLVGTVNMDRAYNIWIRALIKAGFLNNPADFLQKISPLEGCELEVFRYNSMVFQLLKENNLDGVYDILTEMMVRGVSPNKKTMNAALCFFCKAGFVDEALELYRSRSEIGFAPTAMSYNYLIHTLCANESVEQAYDVLKGAIDRGHFLGGKTFSTLTNALCWKGKPDMARELVIAAAERDLLPKRIAGCKIISALCDVGKVEDALMINELFNKSGVDTSFKMFTSLIYGSITLMRGDIAAKLIIRMQEKGYTPTRSLYRNVIQCVCEMESGEKNFFTTLLKFQLSLWEHKVQAYNLFIEGAGFAGKPKLARLVYDMMDRDGITPTVASNILMLQSYLKNEKIADALHFFHDLREQGKTKKRLYQVMIVGLCKANKLDDAMHFLEEMKGEGLQPSIECYEVNIQKLCNEEKYDEAVGLVNEFRKSGRRITAFIGNVLLHNAMKSKGVYEAWTRMRNIEDKIPEMKSLGELIGLFSGRIDMEVELKRLDEVIEKCYPLDMYTYNMLLRMIVMNQAEDAYEMVERIARRGYVPNERTDMILERANRILEERNSRSNLGRNGWNSRQRQLE
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g71210, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TAL_LEPBP
Sequence: MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLATDAPTMIKEGLELSKIAENVVVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAKAGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQILAASVRHPIHFKEVALRGADCVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POC1_TETTS
Sequence: MKKTTIASSAVASQKQTQSKLGNTSSKITEQQTTHDPALSRSFRGHEDIITCADFDPKMRQVASCSKDSIVYVWNFKPQQRPFKFVGHKGAVYCVKYSPDGETIASCGQDRQIRLWQNTVQSKCSIIKAHCGAIRSMSFSADGGYLLSSSDDKTLKLWRLQDKKFMCSFAGHKNWVRSGVISPDMRLVASGSDDKTVMLWDLNFQKIVSKYSTLDDNVKISQINSYSDHMDTVSQVLFHPDGTCLISSSFDHKIKITDIRSNKLIQHYNAHDAQVNSISIHPTGYFLASAGSDSKIKIWDLRQGRQIYTLYSNDKDITTVQFNQSGDYFATGGSQNLCMVWKTNFDQNIQNIEQVQRSTVRQNDVEYSSGGLYAQTLFKTNKTASLSPSKKTISIIPPQQLQDTFNNRGDDELNNGRVHENKQSNSPTFSQQQQQQQLNLSENQYPGLEIVGNQFNLQQSTLSNNNNQNNLIKSQNDSIVSNKNAIPFHPSSEFQQSAVQQQFSQQPKLVVNNGTATYPSNFVPKVEEENIMTEAIAASMQQIYSRLDTMFQYMTNLENRVVQSEQLQKSFVSQNHQNTLDPKQQTMNFGYSNIQDHSLSASLNDRNVVNIFQAGALANTGSIEASLINKQQEE
What is the function of this protein?
Required for structural maintenance of centrioles, ciliogenesis, and cilia-based motility.
What are the official names of this protein?
POC1 centriolar protein homolog.
What is the protein family that this protein belongs to?
Belongs to the POC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: NNJA5_MAIZE
Sequence: MASRDFLGGFGRDGGQAPVGGAGAAPGPGGESDEIELSLGLSLGGCFGAEPSQEGRSADPRLQRSSSVASICSLPAATTGTSCGAQDAGPGPAAAPPPDLLRTSSLPAEYMEDRLRRRAMQSQRRLEAKRKRLERRNSMSSGRPVPAAGGRDDGLEHTVPSGFQLRRSVALTTAGSPTPSRPQQGPADRRAAEATGPDGAACHDEPQPLPLRLRTLRSLTMRTASTGDLRSAMAEDMPMVSYKAEGPGGRKTDGFLYKYRKGEEVRIVCVCHGSFLTPAEFVEHAGGGEVPNPLRHIVVNPQQSVFL
What are the official names of this protein?
Ninja-family protein 5.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4QJ_SINFN
Sequence: MARSGPEVADIFRRYGEAYRAQHTSLSTAQRRVMTAIELCRTAALGGHVEACDQCGHRRIAFNSCRDRHCPRCQSLARAQWLEDRRAELLETQYFHVVFTLPEAIAAIAYQNKALVYGLLFRATAETLRTIAADPRHLGAEIGFFAVLHTWGQNLLHHPHLHCVVPGGGFSPDGTQWIACKPGFFLPVRVLSRLFRRLFLEHLEKAFDGGKLQFFSDLRALNERNAFRRYLAPLRKAEWVVFAKPPFAGPEQVLDYVGRYTHRVAISNNRLVDIEDGAVRFRWKDYRHGDRQKVMTVSTDEFIRRFLLHVLPEGFHRIRYYGFLGNRYREQKLAQCRDLLGMSVPAPSETQAPKEYRDRYEELTGRSLRQCPACHQGQMITIEIFDGVTGPPRCWDTS
What are the official names of this protein?
Putative transposase y4qJ.
What is the protein family that this protein belongs to?
Belongs to the transposase 32 family.
Protein: HIS3_NITEU
Sequence: MTDKWLDTINWSADGLIPAIAQDKNNGKILMVAWMNREALKRTVESGEAVYWSRSRKKLWHKGEESGHTQKISAIHLDCDEDILLLSVEQKGGIACHTGRQSCFFRQLKNGEWVVTEPVIKDPSQIYTK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_BBMV
Sequence: MSKFVAADEYIVPSFQWLLGPTSSQVESFDSSVAGWIKRYEDESKRPESTVDGSCESFVLAVKPVMIGGQCEPAYDQAKWAETCLNVTNLASGLTGVRLIPLPEMARMIYLDEEDSFVDESEVDDWYPEDTSDGFEYLSADGSDYHQNSEPEEEVLDKSNGTLESEEARHETDVKSICSFRDIPVETTMGHRYLALSEEFASIEVDYQVSSIVTPLNKGSIYMTLDVHEETHPKSGIQDKASIERLEAAGHNALKTHAYFDDSYYEGFEESADFSSDFQRLKIKQSHVDWYKDPDKFFEPVLNFGASSRRVGSQKTVLTALKKRNADVPELSDVVDATEVPICLRQSYLNIYGADCLFESFNIMAKGLDYHKRWKSHKELQGVTLLCETNLQRYQHMIKSDVKPTVTDTLHVERDVPATITFHGKGVTSCFSPFFTACFEKFSLALRESIYVPIGKISSLELKSKALNNKFFLEADLSKFDKSQGELHLEFQRLILINLGFPVPLTNWWCDFHRSILSRWTLRPGVSIPLLSKTNRGCFHLLWEHFSDNAMMAYCFDMSTAELAMFSGDDSLVICGSKPEFDPGVFQSLFNMEVKVMDPSLPYICSKFLLESEFGDVFSVPDPMREIQRLQKRKIPKDVQVLRADFDSFCDRMKFLDRLSELSLSVLCRLTALKYCKPGIEGDVRAWLSGFAYYRENFLRYSECYVTDGIHCYRRVDPMSRFKPIDKFQRSDKEWFHDWRNNEFPKKPIDKMARMFGAYKGPVNNDRVERKAKYKVNAAMHDPFALAYERRYVQELELKNDKGNCSVLRE
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: RL27_CHLT3
Sequence: MAHKKGGGSTKNGRDSNPQYLGVKAFGGQEVSAGSIIVRQRGTAFKPGKLVGIGRDHTIFALQSGKVFFRSGRNNKKFVDIIPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL16_VARPS
Sequence: MLQPARRKFRKEQKGRNTGVATRGNSVAFGDFGLKCTDRGRLTARQIEAARRAISRHVKRGGRIWIRVFPDKPISTKPAEVRMGNGKGNPEYYVAEIQPGKIVFEIVGVPEELAREAFRLAAAKLPLRTTFVARQLGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DEF_CHLCV
Sequence: MIRELEYYGSHILRRKADIIPEITDATRQLVQDMYETMVAHKGVGLAAPQVGESLSLFVMCVEGETEEGDLIFCDFPKVYINPVLSNPSEDLVIGREGCLSIPGLRADVYRPQSITVTAVNLDGQEFTEHLEGFPARIIMHENDHLHGVLYIDKMEEPKDIKKFKASLEKIRRRYHAHVKPEDRAS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: MOAC_ECO7I
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: BLE3_ORYSI
Sequence: MAKVHRLMNAVLRLAAAAAAATAAVVMVTSRETTSFFGIQMEAKYSYTPSFIFFVVAYAVAAAYSLLVLAVPAGSALSRLALTTDVVLGMVLAGAVASAGAISDIAKNGNSHAGWLPVCGQIHAYCNHVMAALIAGFVALAVHFVVVMYSLHIVTDVICPCH
What is the function of this protein?
Involved in cell elongation in rice through dual regulation by brassinolide and auxin.
What are the official names of this protein?
CASP-like protein BLE3, CASP-like protein 1C2, OsCASPL1C2, Protein brassinolide-enhanced BLE3, OsBLE3, Protein BL-enhanced 3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACKR2_MOUSE
Sequence: MPTVASPLPLTTVGSENSSSIYDYDYLDDMTILVCRKDEVLSFGRVFLPVVYSLIFVLGLAGNLLLLVVLLHSAPRRRTMELYLLNLAVSNLLFVVTMPFWAISVAWHWVFGSFLCKVISTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKAQFRNLLLIVMVWITSLAISVPEMVFVQIHQTLDGVWHCYADFGGHATIWKLYLRFQLNLLGFLLPLLAMIFFYSRIGCVLVRLRPPGQGRALRMAAALVIVFFMLWFPYNLTLFLHSLLDLHVFGNCEISHRLDYTLQVTESLAFSHCCFTPVLYAFCSHRFRRYLKAFLSVMLRWHQAPGTPSSNHSESSRVTAQEDVVSMNDLGERQSEDSLNKGEMGNT
What is the function of this protein?
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis.  Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.  Acts as a receptor for chemokines including CCL2, CCL3, CCL3L1, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL17, CCL22, CCL23, CCL24, SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.  Upon active ligand stimulation, activates a beta-arrestin 1 (ARRB1)-dependent, G protein-independent signaling pathway that results in the phosphorylation of the actin-binding protein cofilin (CFL1) through a RAC1-PAK1-LIMK1 signaling pathway.  Activation of this pathway results in up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.  By scavenging chemokines in tissues, on the surfaces of lymphatic vessels, and in placenta, plays an essential role in the resolution (termination) of the inflammatory response and in the regulation of adaptive immune responses.  Plays a major role in the immune silencing of macrophages during the resolution of inflammation.  Acts as a regulator of inflammatory leukocyte interactions with lymphatic endothelial cells (LECs) and is required for immature/mature dendritic cells discrimination by LECs.
What are the official names of this protein?
Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine-binding protein 2, Chemokine-binding protein D6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Cell membrane; Multi-pass membrane protein. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via clathrin-coated pits. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane (By similarity).
Protein: ATPE_WELMI
Sequence: MNLNLRVLTPNRVVWDSPVNEIILSTNSGKIGILPNHASLVTAVDIAVMQIRINSQWSTIVLMGGFAKIDNNELLLLVYDAEKGVDIDPQEAQETFNKAKTNLNKAEGKRQKIEADLAVKKARTRLEAINVLTPTSISN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MTGA_AZOSB
Sequence: MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARLRHTWVPYEQISIHLKRAVVAAEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQLAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYLNVVEWGNGIFGAEAAARRYYGLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MURC_TREPA
Sequence: MKRGTLPKDVSGIKIHMIGIKGTGMSALAELLCARGARVSGSDVADVFYTDRILARLGVPVRTPFSCQNLADAPDVVIHSAAYVPEENDELAEAYRRGIPTLTYPEALGDISCARFSCGIAGVHGKTTTTAMIAQMVKELRLDASVLVGSAVSGNNDSCVVLNGDTFFIAETCEYRRHFLHFHPQKIVLTSVEHDHQDYYSSYEDILAAYFHYIDRLPQFGELFYCVDDQGVREVVQLAFFSRPDLVYVPYGERAWGDYGVSIHGVQDRKISFSLRGFAGEFYVALPGEHSVLNATGALALALSLVKKQYGEVTVEHLTALRKVLALFQGCRRRSEVLGEVRGILFMDDYGHHPTAIKKTLRGLKTFFPERRIVVDFMSHTYSRTAALLTEFAESFQDADVVILHEIYASAREVYQGEVNGEHLFELTKRKHRRVYYYEAVMQAVPFLQAELKEGDLFVTLGAGDNCKLGEVLFNYFKEEV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_ECO7I
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLIHDKILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPAIKDGNILEIAQRENEATCFGRRTPEDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHSHAPAAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPKIDMQETIDETLDFFLRTVDLTDKQS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: NU1C_AMBTC
Sequence: MIIDTTEVQAINSFSRLESSKEVYGLIWLFIPIFTPVSGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQAIADGTKLLFKEDLLPSRGDIRLFSIGPSVVVISILLSHLVIPFGYRLVLADLSIGVSLWIAISSIAPIGLLMSGYASNNKYSFSGGLRAAAQSISYEIPLTLCVLSISLLSNSSSTVDIVEAQYKYGFWGWNLWRQPIGFLAFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYLASYLNLLVSSLFVTVLYLGGWNLSIPYIAIPELFRINRIGGVFGTTISIFFTLAKAYLFLFIPITTRWTLPRMRMDQLLNLGWKFLLPIALGNLLLTTSSQLFSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TPIS_CHLTA
Sequence: MFTDKETHRKPFPTWAHLLHSEPSKQFVFGNWKMNKTLTEAQTFLKSFISSDILSNPQIITGIIPPFTLLSACQQAVSDSPIFLGAQTTHEADSGAFTGEISAPMLKDIGVDFVLIGHSERRHIFHEQNPVLAEKAAAAIHSGMIPVLCIGETLEEQESGATQDILLNQLTIGLSKLPEQASFILAYEPVWAIGTGKVAHPDLVQETHAFCRKTIASLFSKDIAERTPILYGGSVKADDARSLSLCPDVNGLLVGGASLSSENFLSIIQQVDIP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM336_CONVE
Sequence: MLKMGVVLFIFLVLFTLATLQLDADQPVERYAENKQLLSPDERRDIILHALGQRRCCDPDWCDAGCYDGCC
What are the official names of this protein?
Conotoxin VnMLKM-02.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MMS2_YEAST
Sequence: MSKVPRNFRLLEELEKGEKGFGPESCSYGLADSDDITMTKWNGTILGPPHSNHENRIYSLSIDCGPNYPDSPPKVTFISKINLPCVNPTTGEVQTDFHTLRDWKRAYTMETLLLDLRKEMATPANKKLRQPKEGETF
What is the function of this protein?
Has a role in the DNA error-free postreplication repair (PRR) pathway.  Lacks catalytic activity by itself.  The UBC13/MMS2 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.
What are the official names of this protein?
Ubiquitin-conjugating enzyme variant MMS2, UEV MMS2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: HSLV_SHEDO
Sequence: MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNARKVRRLYHNKVLAGFAGGTADAFTLFERFEAKLEMHQGHLLKSAVELAKDWRTDKMLRKLEAMLVVADTEASLIITGNGDVVQPEHDLIAIGSGGNYAQAAALALLQNTELSAQEIADKSLTIAGDICVFTNQFKTIEQLDY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.