PharMolix/UniProtQA huggingface dataset:
Protein: VP7_ROTBV
Sequence: MYGIEYTTILISLTSITLLNYILKSITRMMDYIIYRFLLIAVILATMINAQNYGVNLPITGSMDTAYANSTQNEPFWTSTLCLYYPVEASNEMADTEWKDTLSQLFLTKGWPTGSVYFKEYTDIAAFSVEPQLYCDYNLVLMKYDSTQELDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTVQVCPLNTQTLGIGCLITNPDTFETVATPEKLVITDVVDGVNHKLNVTTATCTIRNCEKLGPRENVAVIQVGGANILDITADPTTTPQTERMMRINWKKWWQVFYTVVDYVNQIIQTMSKRSRSLNSSAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: TRMD_HAEIG
Sequence: MWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGKQASAEEDSFADGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_ENDTX
Sequence: MTLSFHYNRNDTKIMDIIVISGPTASGKTKKAVEFCKEKNGEIISCDSRQIYKYLDTGTNKEGVFLQNGLRRIDGVLQHLTDILNPDQNYSAAKFVKDADLKISEILKKGKVPVVTGGTGLYIKALLYGLDEMPKADKTLRKELKTKSQDELYSVLLKSDPEAAEKNKKNPQRLLRALEVNILSGRTMQEHFKSKSPRYNFGHYSISVDNKILYKKTNERCKYMIESGMIEETQKVLNMGFDKNCSALSGIGYRHIIQYLEKKISKEDLILEFSKDTRHYAKRQNTWFKAQPDVDFMFY
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MRO2A_MOUSE
Sequence: MKEATELNEDMLEEAEHLALLEPEDDGTFFQVTNLLNIMDSESAKTDTTGPGLDMRKTLASVIITEKATTDPCVVMNALIRCLQMPEISTQRKMNIYNIMQEIIQQEGEMEEHCIQRLVAIASKQMRDITEAEDFETAEVASETLVALSRNHFSLVMYELQHHLKPLNLTDEFVIVTLAKLANGNVFEFMPYMGITLATIFTMLRLANEAKMRQVICSAMETFCETVQFYLRHLEDSLYPVMTEDQFAVKLFPMYRYFVTVWLRHQDLEVKLGVIKSLRPMLSLLLPNDDLREQVYDYIPLLLAEFQGTGHWPLFPSLLQVLRQILEASVTTNTPIPPMLLHPIFTELHVQVCSKAPAQQQFSSQNLMEIVHCFIALARSYPKELMKFFFSQVEMSKEAVRVGTLALIRAVVSADDPKINIKTIYLAIRVVKNTLSDTRSKVRMAILRIIGQLVLSGFQEKIKGWGLKYVSVQLTLSTYKLTNRRECFYQRDLEEKMVHKVTMDTVKIITSSISGMTNEFWVRLLCYIMETDYTEALTPICISLTNLAENQIHGKDTEAGIAGKSKHVDLPAPQKLLARLLVLMSSPYKGEGRGIAMLNLLRTLSQSIAPSMADMWEQEIPLLVQYLEEHTEFTWNQKTWEDMLIQFLRNSLKKTRGTSWSLRLSKELNNQIETFDSPSLEKGFLYRALGFTLGMGLEADRVEVLLLELLYKTDYSNDFDREGVILCFGLCARGQVKTVLNVLQDFEERIQESEQSWQIGAWRKDHPWRRETVKSALMVMYSCVSSYCHPQMLLTHVDSPITSKIIHHYSSSCQDISLKMAFMKSVVQVTNAIKSIQDPEDFQFAHKSALTGLIVVIIKAEPPDHLVSPVRSMAMDALSQLSTMKPFYSPEESTELMDISIHTVISLQPPGEDNESVKTLYANTMSSLKQLMEGLLQRQLDPKGLQDTVHLLEKWILSEKEWEREKAMALHLHLMQIYVQSIGVCIPLKLGQFGVLVGLIAPCTCDAHRRTRLASINVLSSLLDLHVSQTCSLWGTSKEQELQKCKEDLQDTDMNKISSASSRVAKVVCPEFNCDEVVSLIQKLCENIGAMDLQHDRAAVTWIGIFLQMRVKELEDKVAEILGAILVHLPVVDHPEVRRHLIEGILLLAHYHQETVLTSLLRQPLPMESHLTEVWLAVAENVPFARTMLHGLLGRLQSRFTAKINATSKADIWRLAAVDPLMTLCTIQLLMEKMDQDDKFPDLFPDLLYTFLLQLGSSHGPEAASPVLKTWRLVHTGPLPQEMTLQRCSRSRITIKSMQLLVKRINREPLEQALEEQSVWSLLENGGTFLEGVSLMARLCMQNMENYMQRLAELVLTGMGSEILSCCISSTAICVEFMSDPVLHQEKLLRPVVLMLEKGAGQDKDETLQVLSLRALGNMALGAPRKVKQYRKLLLEKCLGSLQGQVSSSAMAEGMEALTKVLAELREGDIGSSFEAISKQCRAFFDNESELLRLKAFVLFGKLTKVVGISKKHFFKGEVKRGWVSLLLHCQDPCPSVAQACVATMFQCVHFWGWKSLESSFGHSNDSINEQMTVFQTNMCSVLAQKKPAVLCGFLLETTVFMKNNLSRIRIAACNLAGIIMKQLSAHYLKKMDLVGLRNSLQDLQLDSDAGVRRAALETLKVLDSCNQHWLLASPRGLP
What are the official names of this protein?
Maestro heat-like repeat-containing protein family member 2A, HEAT repeat-containing protein 7B1.
Protein: YHCE_BACSU
Sequence: MNSFLGLLKKDIKLSRMWLLVWICGIIFLLGTGHIIASRTKEPLVIFGFFVAVAFFLLFLSPVFVFYHLRKEGKSQLWLYNPNGGLWLFSSKLAASLLYQFVIQLALTAYGIWMYHMLSVKNLLEHQVDITSTVALLNMYGLISSLDMSVTVIVFWTVFHSLRNWRGMRWAAMVLLVAMWLFFDEYIISPLVESQKHFWPVTVYCNFDFHFHNVWRLELKPIHLSVLGFPIAIVITFLLLIMASKLLDRKVEV
What are the official names of this protein?
Uncharacterized protein YhcE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURR_ALIFM
Sequence: MATIKDVAKLAAVSTTTVSHVINKTRFVAEATQKRVWEAVEELNYAPSAVARSLKCNTTRTIGMLVTQSFNPFFAEVMHGVENYCYKQGYTLFMCNTEGDLEKQKHYLRMLAEKRVDGLLVMCSDLNEQLLTLLEKNTELPMVIMDWGPDSPRTDKIIDNSEEGGYLATKHLIENGHTHIACITGQADKVTCKERVRGFERAHADANLSFNPEWILEGDFECASASKAVDKILSIEESKRPTALFCFNDIMALAAISKIQQSGLRVPEDISVIGYDNIELSAYFSPPLTTIHQPKRRVGKTAVEILLERIKDKDHERRVFEMQPEVVTRSSVLNRLK
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: CSPLG_ARALL
Sequence: MAKLALAATSGKSCKILLGLRLLAFSATLSAAIVMGLNKETETFVVGKVGNTPIKATFTAKFDHTPAFVFFVVANAMVSFHNLLMIALQIFGGKMEFTGFRLLSVAILDMLNVTLISAAANAAAFMAEVGKNGNKHARWDKICDRFATYCDHGAGALIAAFAGVILMLIISAASISRLAQQNKCCSTTASPSVVP
What are the official names of this protein?
CASP-like protein 1B1, AlCASPL1B1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPEE_BIFLO
Sequence: MVEPAIGRNHIRAGRHHGRARIVFARTKNHAYLSHDAYCSRYPPIGRENADRLRIRTVVDRRTGRGAERWHRSPRQANGRFSNQRYSSTSPNSSPACPLIYFISIKAKRIACVVSAVIFVATSCVSPLTGFAFWETNLAYEGESIYNYLQVKNLSDRTILSTNVLFGVQSVTMKDKGLTGMYYDTALAAPALADNANSALILGMGTGTYARQLKQYYPKMNITGVEIDQKITDLAGEYFDEPADIPVTTYDGRAWLAASHDKYDVIMVDAYQDITIPFQMSSTEFFTMVREHLNPGGVMVVNMNMISDGQGSINEALSDTIASVFGNGNTLTADVPNTTNRELFAKKPGSGSEENSMQQASKALNLRETTYERTGSEDLEWYMEEVASRFRKVNEPDSASTILTDDKAPVEVLGMHAIDQIIADEAGPYRQILKDEGFGGLLRAVQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Probable polyamine aminopropyl transferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_ECOSE
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSTB1_VIBVY
Sequence: MYSFNDTLGYHAPLDVNNLPDDKTAITIENLDLHYGQSQALYDISMRIPKGRVTAFIGPSGCGKSTLLRCINRMNDLVEGCKVTGSVKLYGSNVYDPSVDVATLRRRVGMVFQRPNPFPKSIYENVVYGLRLQGVKNSRTLDDAVERSLRSAALWDEVKDRLHENAFGLSGGQQQRLVIARAVAIEPEVLLLDEPTSALDPISTLTIEELINDLKTQYTVVIVTHNMQQAARVSDYTAFIHMGKLIEYSDADTIFTSPMKKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL36_LEUMM
Sequence: MKVRPSVKKMCDACRVIKRNGRTMIICSANPKHKQRAGK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: VM3V3_AGKPL
Sequence: MIQVLLVTLCLAAFPYQGSSIILDSGNVNDYEVVYPRKVTALPKGAVQPKYEDTMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSIEDHCYYRGRIQNDADSTASISACNGLKGHFKLQGEMYLIEPLKLPDSEAHAVYKYENIEKEDEAPKMCGVTQTNWKSDEPIKKASQLVVTPEEQRYLNTKKYIELVIVADNVMVKKYTSNSTAIRTRIYACVNTLNLIYRAFNIYIALIGLEIWSNRDLINVQSASSVTLDLFGTWRETVLLRHKRHDNAQLLTGINFDGDTVGLAYVGSMCDPKRSAGIIQDHNKLDVMVAIAMAHELGHDLGINHDGNQCNCGGNPCIMSATLNFEPVYRFSDCSRDEHWRYLIDNRPPCILNKPSITDIVSPPVCGNYFVEVGEECDCGLPAHCQNPCCDAATCKLRPETQCEDGECCEQCQFTRAGTECRAARSECDIAESCTGQSAECPTDDFQRNGQPCLNNNGYCYNGTCPILTNQCISFFGSSATVAPDVCFDFNLQGQGNFYCRRERARIFPCAPQDKKCGRLFCVKGPIGNTISCQSTSSQSDLDIGMVDLGTKCGDGRVCNSNRQCVDVNTAY
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like VMP-III, AplVMP-III, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS7_ENDTX
Sequence: MKQRKAKITRKTKETNIVVEINLDNILLPSVSTTIGFLDHMLELFAVHSGIGFKIKASGDTHIDDHHLVEDAGITIGQALKEAVGDKKGIVRYGHFLLPMDETLSYVALDLAGRFYLSYEADIKFQKNGFNYDLIQEFFYALASNAGITLHIKMIKGRNNHHIAESIFKAFGRALRQAVSYSKSKKTVPSTKGIL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSZ_ECOLI
Sequence: MPLLNDLLDFSDHPLMPPPSAQLFAEHLPTEWIQHCLTLSAHATVRRRRLPGDMVIWMVVQNEPITDVVRRLNLSADGEAGMNLLARSAVTQARQRVGAAPVEWLFRQTAQDRGAERYLKDDWHGLQLFAIDGAQFRTPDKPELREYYGSANTSTKRQNAYPVMRLVALMNLGSHILLNAVTAPYRQSETVLAHSMLATIPDNSITLFDKLFYSEDLLLTLNQKGCNRHWLLPAWKNIASEMIELGNTASPGTIPKRLEHLRGALEVVFITKRPRPSRPRSVKISKTRYPVKHSAAPLK
What are the official names of this protein?
Putative transposase InsZ.
Protein: S2538_AJECN
Sequence: MLATADMSDGYTNGARLKISTSSKPKFHFIAGLASGLSSAILLQPADLLKTRIQQAHQTSALLFTIRKILASPQPIRGLWRGTLPSALRTGFGSALYFSSLNALRQCIANQGALVPLHGDRDDKRTRTSALPKLSHTANLLTGAMARTAAGFIMMPVTVIKVRYESDYYAYRSIWGAGRDIVRSEGFRGLFSGFGATAIRDAPYAGLYVVFYEQSKKNLNALNFGGLTTARPLSDEPAREDNSEKQLVTSSISVNFVSGALAAGLATSITNPFDVVKTRLQLMPNKYRNMAHAVRLVLREDGVRSLFGGLGLRMGRKAISSALAWTVYEELILKAEKRWPDQDNIEQLTP
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_ORCBR
Sequence: MTNIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGIPSNMDMIPFHPYHTFKDILGALLLILVLLTLTLFTPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGSQPVEHPYIIVGQLASILYFLLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYL_PELPD
Sequence: MEQKYNPAAVEQKWQQQWETGASFAVNEQSDRPKYYLLEMFPYPSGRIHMGHVRNYSIGDVIGRFKRMRGFNVLHPMGWDAFGMPAENAAIQNKSHPAKWTYENIDYMRGQLKKMGLSYDWGRELATCDLEYYRWEQKIFLEMFAKGLAYKKTSYVNWCPTCETVLANEQVEDGACWRCDSPVQQKELDQWFFRITQYAEELLSYTEKLPGWPERVLVMQKNWIGKSHGCEVDFPLEGGTGSVRVFTTRPDTLFGATFMSLAPEHPQARELTTPDRRDEVERFIEKVRNTDRSKRTADDYEKEGVFTGSYCINPLTQVRMPIYLANFVLTDYGTGAVMAVPTHDQRDFEFAKKYGLDLKVVIQPEGTTLDPATMEAAYTEPGIMVNSGTFDGMGSEEAKQAIADHLQEMGGGTKTVTYRLRDWGISRQRYWGNPIPVIYCDCCGVVPVPEKDLPVRLPMDVEFTGEGGSPLARLESFINVPCPTCGKPARRETDTMDTFVQSSWYFLRYCCPDFHDAPLDRTRVDYWMSVDQYIGGIEHAVLHLLYARFFTKVLRDLGYVECSEPFTNLLTQGMVIKDGAKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWNDQGVDGSFRFLNRVWKLVNDRLELISGAAPLDVPGLTGEERTLRRAVHKTIRKVTEDIEGRFHFNTAIAAVMELLNVLQSADLSTPQAGAVMKEALESLVLLLAPFVPHMAEELWQRMGQPGALSTTPWPEYDREAAVDDEVLMVVQVNGKLRSKITVAAGSDEESLKALALADDKVQPFLQGVQVRKVICVKGKLVNIVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XNI_ECO24
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: PCRB_BACSU
Sequence: MYDVTEWKHVFKLDPNKDLPDEQLEILCESGTDAVIIGGSDGVTEDNVLRMMSKVRRFLVPCVLEVSAIEAIVPGFDLYFIPSVLNSKNADWIVGMHQKAMKEYGELMSMEEIVAEGYCIANPDCKAAALTEADADLNMDDIVAYARVSELLQLPIFYLEYSGVLGDIEAVKKTKAVLETSTLFYGGGIKDAETAKQYAEHADVIVVGNAVYEDFDRALKTVAAVKGE
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.  To a much lesser extent, is also able to use geranyl diphosphate (GPP; C10) and geranylgeranyl diphosphate (GGPP; C20) as the prenyl donors, but not farnesyl pyrophosphate (FPP; C15).  Cannot use glycerol-3-phosphate (G3P) or 3-phosphoglycerate (3PG) as an acceptor.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: RHAL_RHIME
Sequence: MTLMISTSVLDAENASRRDALTRDYESLGDRLARRGIDIDAVKAKVAAYGVAVPSWGVGTGGTRFARFPGPGEPRNIFDKLEDCAVIQQLTRATPAVSLHIPWDKVSDLGALKEKGSALGLSFDAMNSNTFSDAPGQAHSYKFGSLSHTDSATRRQAIEHNLECVEIGKALGSKALTVWVGDGSNFPGQSNFTRAFERYLDSMKAVYAALPDDWRIFTEHKMFEPAFYSTVVQDWGTNYLIAQELGPKAFCLVDLGHHAPNVNIEMIVARLIQFKKLGGFHFNDSKYGDDDLDTGSIDPYRLFLVFNELVDAETRAANGFDPAHMLDQSHNVTDPIESLMTSAMEVGRAYAQALIVDRKALAGYQEENDALMASETLKTAFRTDVEPILATARLENDGAIAPVAAYRASGYRARVAAERPAVAGGGGGIV
What are the official names of this protein?
Probable sugar isomerase R00627.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
Protein: OR7AA_HUMAN
Sequence: MKSWNNTIILEFLLLGISEEPELQAFLFGLFLSMYLVTVLGNLLIILATISDSHLHTPMYFFLSNLSFVDICFVSTTVPKMLVNIQTHNKVITYAGCITQMCFFLLFVGLDNFLLTVMAYDRFVAICHPLHYMVIMNPQLCGLLVLASWIMSVLNSMLQSLMVLPLPFCTHMEIPHFFCEINQVVHLACSDTFLNDIVMYFAVALLGGGPLTGILYSYSKIVSSIRAISSAQGKYKAFSTCASHLSVVSLFYGTCLGVYLSSAATHNSHTGAAASVMYTVVTPMLNPFIYSLRNKHIKGAMKTFFRGKQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 7A10, OST027, Olfactory receptor OR19-18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSD_BACFR
Sequence: MKEEYKLSHLKELEAESIHIIREVAAEFENPVMLYSIGKDSSVMVRLAEKAFYPGKVPFPLMHIDSKWKFKEMIQFRDEYAKKYGWNLIVESNMEAFHAGVGPFTHGSKVHTDLMKTQALLRALDKYKFDAAFGGARRDEEKSRAKERIFSFRDKFHQWDPKNQRPELWDIYNARVHKGESIRVFPLSNWTELDIWQYIRLENIPIVPLYYAKERPVVQMDGNLIMADDERLPEKYRDQIEMKMVRFRTLGCWPLTGAVESEADTIEKIVEEMMTTTKSERTTRVIDFDQEGSMEQKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: GATA_DESAP
Sequence: MRLYDLTAHRLRELLLGREVSAAELCRSVLNRIDEVEGRVKAYVTLDREGALRQAAAVDRELQNGRELPPLAGIPFAIKDNICLRGLPATCSSKILHNWVPPYDATVVEKLKDQQTVILGKTNMDEFAMGSSTEHSAFFTTRNPWDPKRVPGGSSGGSAAAVAAGSAICALGSDTGGSIRQPASFCGVVGMKPTYGLVSRYGLVAFASSLDQIGPLTRDVTDCALVMNAICGHDHRDSTSVPKEVPDFTSFLVDDVKGMRIGLPREYFPAELDDGVRRIVMEAVSVFEERGAYVEETSLPHTEYALPVYYLIAPAEASSNLARYDGVRYGYRAPECEDVLDMFRVSRSRGFGAEVKRRIMLGTYALSAGYYDAYYLKALKVRTLIRRDFEEAFEKFDVLLSPTAPETAFIIGAKTEDPIRMYLSDIFTLAVNLAGLPGMSVPAGFVAGLPVGIQFIGKPFAEGTLLRMGYAFQQSTDHHRQRPPETPGGEIS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ST65G_HUMAN
Sequence: MNLQRYWGEIPISSSQTNRSSFDLLPREFRLVEVHDPPLHQPSANKPKPPTMLDIPSEPCSLTIHTIQLIQHNRRLRNLIATAQAQNQQQTEGVKTEESEPLPSCPGSPPLPDDLLPLDCKNPNAPFQIRHSDPESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHAGFDCANESVLETLTDVAHEYCLKFTKLLRFAVDREARLGQTPFPDVMEQVFHEVGIGSVLSLQKFWQHRIKDYHSYMLQISKQLSEEYERIVNPEKATEDAKPVKIKEEPVSDITFPVSEELEADLASGDQSLPMGVLGAQSERFPSNLEVEASPQASSAEVNASPLWNLAHVKMEPQESEEGNVSGHGVLGSDVFEEPMSGMSEAGIPQSPDDSDSSYGSHSTDSLMGSSPVFNQRCKKRMRKI
What are the official names of this protein?
STAGA complex 65 subunit gamma, Adenocarcinoma antigen ART1, SPTF-associated factor 65 gamma, STAF65gamma, Suppressor of Ty 7-like.
What are the subcellular locations of this protein?
Nucleus.
Protein: BETB2_RHIME
Sequence: MATPLCQPAASHFIDGTFIEDRTGPEILSVNPVDGEIIAKLHGATSCIIEKAIASAKRAQKEWARKEPAERGRVLSRAADIMRARNRELSVLETRDTGKPISETLVADAASGADCLEYFGAIAATLSGDSIQFGEDWVYTRREPLGVCLGIGAWNYPIQIAAWKAAPALACGNAMIFKPSEVTPLSALKLAEILTEAGLPPGVFNIVQGAGDVGAELATHPAIAKVSLTGSVKTGARVASAAMAGIRPVTMELGGKSALIVFDDADVEAAVSGAILGNFYSAGQICSNGTRVFLQRGIREAFLARLLARVAALKIGDPMDEETDIGPLVSAAHRNRVATYVARAEVEGAYQMAPPRKLPPGDAWHEPVVFTNVTDWMTLAREEVFGPVMAVLDFDDEQDVVARANATDFGLAAGIFTRDLVRAHRLAAELEAGTVWINAYNLTPAGMAFGGIKRSGIGRENGRVAIDHYTQLKSVFVSMQT
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase 2, BADH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: HBB_CARAU
Sequence: VEWTDAERSAIIGLWGKLNPDELGPQALARCLIVYPWTQRYFATFGNLSSPAAIMGNPKVAAHGRTVMGGLERAIKNMDNIKATYAPLSVMHSEKLHVDPDNFRLLADCITVCAAMKFGPSGFNADVQEAWQKFLSVVVSALCRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SMD1_BOVIN
Sequence: MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D1, Sm-D1, snRNP core protein D1.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.