PharMolix/UniProtQA huggingface dataset:
Protein: RL31B_PSEAB
Sequence: MKPGIHPEYRPVLFHDTSADVYFLIGSTAETDKTHTHTDGKTYPYVTLDVSSASHPVYTGEQRKTKSEGRVAGFNKRFAGFVGGKGA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: CAGE_HELPJ
Sequence: MFVASKQADEQKKLVIEQEVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQAYEPVLIVAIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAANSYLANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTVKKKIVIDETNRDYGLIFSNDFMRAYNEKQKRESFYDISFYLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLSKYHPTRLKEYTKDGIIYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSAIEISEYAPKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTSRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSLVLFADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGKEDNNAWGNSVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFAYNFPANISKDKQKLTMVYMDKDYGAYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKTNATMEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSNTLAAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNKATDRLDFSKTIIGVDGSSFLDNNDVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIREQCPTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKIIQNHSIIDKYQALRQMYQQIKEY
What is the function of this protein?
ATPase component of the type IV secretion system Cag (Cag-T4SS).  Acts as a molecular motor to provide the energy that is required for the export of proteins.  Required for CagA translocation and induction of IL-8 in host gastric epithelial cells.  Plays a key role in Cag-T4SS pilus biogenesis, especially in the localization and stabilization of the pilus-associated components CagI, CagL and the surface protein CagH.  Is also critical for assembly of the entire cytoplasmic portion of the Cag inner membrane complex (IMC).
What are the official names of this protein?
Type IV secretion system protein CagE, CAG pathogenicity island protein 23, Protein PicB.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YNEE_ECOLI
Sequence: MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTEDLQRVLASNSPANRILLIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKILPDRHYQLT
What are the official names of this protein?
Voltage-dependent anion channel-forming protein YneE.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGJ2_NOSS1
Sequence: MSLTASSTPQGFSTFITNLGIRDTTEDFVFLRSDVPCVADGVFTQSLFAGPSVTISRQNLQDGQAQGIIIISKNANVANGAVGIADAQEIIQLVAQETGIAAENLAIASTGVIGRRYPIEKIRAGLVGMGQKLTAADFDLAARGIMTTDTVSKIAARQVGNAKLVGIAKGVGMIEPNMATMLAFFFTDAAISANTLRQIFRSTIDKTFNCLSIDTDTSTSDSAVILANGLAGEVPEAEFASALQEIAHDLVLKIARDGEGATKVIEVTVDSAANYAQAKRVAKAIVNSPLVKTAVYGADPNWGRVAMAIGKCEDERDINPDQVVIRFDEVQVYPNTFQAENLEKLKEIMSKEKVNIHVSLNIGTDVATVWGCDLTEGYVEINGKYST
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ 2.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT4_EPTST
Sequence: SGSCEVKTCWRAMPPFRKVGNVIKEKFDGATEVEMQRIGTRKQLVPKNPQFKPHTDEDLVYISPSPDFCIRDMKAGVPGTAGRHCNRTSKALGGCELLCCGRGFHTAEAELVERCSCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Plays an important role in embryonic development (By similarity).
What are the official names of this protein?
Protein Wnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FABV_XANC8
Sequence: MIIHPKVRGFICTTTHPLGCERNVLDQIAATRARGVRNDGPKKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGSDKKAGTAGWYNSAAFDTHAKAAGLYSKSINGDAFSDEARAKVIELIKTDMGGQVDLVVYSLASPVRKLPSTGEVKRSALKPIGNTYTATAIDTNKDTIIQASIEPATEQEIEDTITVMGGQDWELWIDALDSAGVLAKGARSVAFSYIGTEITWPIYWHGALGKAKVDLDHTAQRLDARLQASGGGANVAVLKSVVTQASAAIPVMPLYISMVYKIMKEKGLHEGTIEQLDRLFRERLYREDGQPAEVDEQNRLRLDDWELRDDVQDACKALWPQVTTENLFALTDYAGYKHEFLKLFGFERKDVDYDADVDPDVKFDCIELG
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: NIFW_SYNJA
Sequence: MSWNHNRRWKDFQALVNAEDYFAFFELPYDPRVVNVNRLHILRKFAQYLAPLEHFQGSEEERLEQARQALEKAYQTFLTSTPQQEKLFRVFQDYGCPDPVGGCAGCSSLGERGECSPGIPA
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: CCQ1_SCHPO
Sequence: MSEINDFTNSIIINESDTKYEVYSEVNSSNRWIAKEDCPSPLEDVWLLKLAGHKRKLEEPLSCMRNEEPASKQREIEKFLRTDLDHSENDFLTQEVDEFPSTQQLFPIPLQNDTAFDSSEESITKSSKSSFSVLDIGLPMSALQRKMMHRLVQYFAFCIDHFCTGPSDSRIQEKIRLFIQSAHNIAKHPSLYDTEVRNPSAAESTNSHVSLDASNFSSYAENSSKFLFLQELFKNLSPSYSKTFFLFISNQFLANTLTQWLKSQNIDAELWAEEDAKTSQHPAIWICVSKKAPSASHFLQSCPDLSATIFYDIEAYMSVTSSLPSIQSLVLRLIHLGSIEHAIKCFQSSYNASFLVNIVGVVATLSSSSEENSEASNLSTLFEKSGNFEEILGSESHSSITEKTRDIAKNVATWLKNGENFSSWPLPPLMDLASLSVAEPRDSQPSVSQVNDTFVKSSDSTFPSSQSMQSPSKLHSLTSNATDLLSSSSLKKNFFSQQEADEVELSNNYDLQGAAVQYLQRRLRMVEDELHEAINSKNVQQSRSEELEQQISKLTDNLQEYRNTVRELKLDLEKSKKKNEDLSKLEVEKVEEIANLKKELTHLAKQQEFGFKYVQEFSNEDLQGKLIEANEKNYKLTQLLKTQKEDADFITNQYQNASTFAAEQSKEVAKLQAECKRLQAINSKVMEEVKVYNDSRVEALLAKVSSLEETLKILEQKSLPKFTPHNQSPRIIDSN
What is the function of this protein?
Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome.  Links telomeres to the meiotic centrosome component pcp1.  Essential for the formation of normal telomere clusters during meiotic prophase.  Required for telomere length regulation and chromosome segregation.  Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).
What are the official names of this protein?
Coiled-coil quantitatively-enriched protein 1, Structural maintenance of chromosomes protein ccq1, SMC protein ccq1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Chromosome, telomere. Note=Associates with major heterochromatin, sub-telomeres, rDNA and the mat locus.
Protein: SCPA_THEPX
Sequence: MYNVKLEVFEGPFDLLFHLIEKNEIDLMDIPISVILDQYMEYIKTLQEMDLNVASEFIVMAATLLEIKSKMLLPKQKFEGQQLEMEEVDPREELVTKLIEYKKYKIIAQTFKEMCKIGSRFFREEPEVKYIDKKIAFNYSSEDIYKAYLKVISKNNAKEDEIEIKKDEYTVESKIKELLVKLVKKTVLWFSEFIKKSRAKGEIIVSFIAVLELVRLNKIIAEQKTTYGDILIKSFGRGEKNEQ
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: G6PI_XYLFA
Sequence: MHNGFDALQLHANRLRGVTIPDLLAAELKRPEQYARQVGPLYFNFARQKYDCVALEALFALARNHNVAGAFQRMFCGEQVNVTEGRAVLHTALRGDLSGTSVAVAAYTAAAKVRERMYALIAGLDASEVTDIISVGIGGSDLGPRLVVDALRPISQGRFRVHFVSNVDGAAMRRTLDMLDPSRTAGILISKTFGTQETLLNGRILYDWLGGSERLYAVSANPERAAHAFDIVPTQVLPIWDWVGGRYSLWSAVGFPIALAIGSQRFEELLAGAAEFDAYALRVPLEENVAVLHGLTAVWNRNFLGCATYAVMAYDQRLALLPAYLQQLVMESLGKRVKCDGTPVDRDTVPVWWGGVGTDVQHSFFQALHQGTNIVPADFIGTIRNDDPYTENHFALNANLLAQIEVLANGQLSDDPHRVYPGGNPSTLILLDALTPQALGGLIAMYEHSVYVQSVIWGINAFDQFGVELGKHLAVQLLPALKGESVEVVDPVTRAVLVRLRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC130_CAEEL
Sequence: MGERKGQNFYYPPDFNYKTHKSLNGYHGTHALRERAKKIDQGILVIRFEMPFNIWCLGCHNHVGMGVRYNAEKKKIGMYYTTPLHEFRMKCHLCDNYYVIRTDPKNFDYELVEGCSRQELRFDPTDIAQIGAVDRGFTQKLAADAMFKKEHEAEDKDKAATEEGRVDKLEWIQERMRDDFTANSFLRAQFRNEKKSLNETRARDANLRDKLSIGTTQLLPETEEDRRIASMMTRYRDTKTHDDHLESSRDRIESRRIFRRPEETDTPSTSSGSSGGAVPSASERLKATMKAERDKRINASFSTAGTSSATQKLLGIKRKSASSLGVQIKKAAPENSSLQDEEPAVEKPNISNPISLIAQEYGNSSDDSD
What are the official names of this protein?
Coiled-coil domain-containing protein 130 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family.
Protein: TRMHL_STAAE
Sequence: MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVGEI
What are the official names of this protein?
Putative TrmH family tRNA/rRNA methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: RUVB_MOOTA
Sequence: MATERLVAGNLHNEDQELELSLRPRCLAEYIGQEHVKETLGIFIQAARERGEALDHVLLYGPPGLGKTTLAGIIANELGVQLRVTSGPALERAGDLAAILTNLQPRDVLFIDEIHRLPRQVEEILYPAMEDFVLDIILGKGPGARSIRLDLPPFTLVGATTRAGLLSSPLRDRFGINSRLEFYQVAELEEIIRRAATILQVAIEPEGAREIARRARGTPRVANRLLKRVRDYAEIRAGGVITREVAREALELLQVDAAGLDSSDRRLLLTLIRKFNGGPVGLETLAAAISEEPDTIEDVYEPFLLQMGYLQRTPRGRVATPGAYAHLGIKPEDRLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS15_SHELP
Sequence: MSLSKEVKAQILADFGRGENDTGSTEVQVALLTAQINHLQGHFKEHIHDHHSRRGLLRMVNSRRKLLAYLKRTENERYQELIKKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RPIA_STRP4
Sequence: MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREKDGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: TRUD_PSET1
Sequence: MSDLNYLYGAPLSKADFKTTAEDFMVDEDLGIEFTGSGEHVCLQVVKKGENTQYVAKLIAQRAGVSPRDVSYAGMKDRHGVCSQWFSVKVPIKKPIDFSDLNSESVFVVSQQRHERKLRTGCHKGNKFTITLRNVTDPLDILCRINAVRSGVPNYFGEQRFGRDGHNLVMAEKMFAGERIRDKKLRGIIISAARSHVFNQLVSLRVKEHGLAKTMHREVFMLSGSNAFFEDAISDENIARLASGDIMMSAPMVGKSEKGLTEQEKVWLGPYQSWCDGLGELGLKNERRMLRLIPQDFSVETIDESTLKLSFGLPKGCFATALLRELVDYTDASPRERKEKDSKDEDPIK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CCS1_CANGA
Sequence: MTANADFYEATYAVPMHCTDCTDDIKKCLNGITGIKDLQFDISQQMMSVNSCVAPSVIINALRDCGRDAIIRGAGKPNSSAVAILETFEDVDLKKDTAVRGLARIVQVSDQKTLFDVTVNGVPFSGKYQAKIHSNGNISEGVKSTGDVYYKFEEPIECSDASDLDKSLYSGQNFVSAPLPIWDLIGRSFVIFREGEPAYDIAGVIARSAGVWENDKQVCACTGKTVWEERKDALKNNIK
What is the function of this protein?
Copper chaperone for superoxide dismutase 1 (SOD1).  Binds copper ions and delivers them specifically to SOD1 (By similarity).
What are the official names of this protein?
Superoxide dismutase 1 copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the CCS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_XANOP
Sequence: MSALRLIVGLGNPGQEHAQTRHNAGFRFVDSLIERSGARWALDSKLFGETAKVDIAGQPVWLLKPATFMNLSGKSITAALRFWKIEPEHLLVAHDELDLAPGTARLKFDGGHGGQNGLRDTIGLLGHGKFHRLRVGIGHPGHKDRVVPWVLGRAGREDDAAIGTAIDAAIDVLPLAMEGHFSEAMKRLHTSRDA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_SHEB8
Sequence: MAEVANNEQQAPQFNIQRVYTKDVSFETPNSPAVFQKEWNPEVKLDLDTRSAKLADDVYEVVLSLTVTAQNGGDTAFLCEVQQAGIFSITGLTEPQLAHSLGAYCPNILFPYARETVGSLVGRGTFPQLNLAPVNFDALFAQYVQQRQAAATAPAAEEANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_ACTSZ
Sequence: MNIQQLLSEKIRHAMIAAGAQQPAEPAVRQSGKPQFGDYQANGIMGAAKKLGLNPREFAQKVLDNLNLDGIAEKLEIAGPGFINIFLSKNWLVCHADEMLSAVNFGIKTAKPQTIVVDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNHVIRANHVGDWGTQFGMLIAYLEKMENENASAMQLSDLEAFYRAAKEHYDNDEAFAEKARNYVVKLQSGDEYCRIMWKKLVDITMRHNQENYDRLNVTLTEKDVMGESLYNPMLPEIVADLKKQGLAVEDDGALVVYLDEFKNKDGDPMGVIVQKKDGGYLYTTTDIAAAKYRCHKLHADRVLVFSDSRQSQHMQQAWLITRKAGYVPDSFSLEHPFFGMMLGKDGKPFKTRTGGTVKLKDLLDEAVERADKLIAERNPDLTAEEKAAVVEAVAIGSVKYSDLSKNRTTDYVFDWDNMLTFEGNTAPYMQYAYTRIRSIFARAGIEPNSLNDDIVLTDDKERVLVIKLLQFEEALNGVAKDGMPHILCQYLYELAGMFSAFYEACPILNAERPIKNSRLKLAALAAKTLKQGLDLLGIKTVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_RUMCH
Sequence: MDTLLFVLKSIVLGIVEGVTEFLPISSTGHLIIFENIMGFKSASPNYVKMYTYVIQLGAIMAVVLLYWKKIKETVINFFPGKVGYEKSGFKFWFMIFIACIPGAAVKLLLDAPVEKYLMTPVSVAIVLILGGLWMIYAEKKFRNNNLGKQKLSVTPKQALIIGAFQCLAIIPGMSRSASTIIGGWVAGLSTVVAAEFSFFLAIPVMFGYSLLEIIRIGGLTSLPAAELISLVVGFIVAFIVAVAVISQFISYLKRKPLKSFAIYRMIFAVIVLIAGFMGFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LFTR_MARMM
Sequence: MRGFGAEELLNCYARGVFPMAEGRDDPRIYLLDPDERGIIPLDQFHASRSLRKTVRQDVYQVTINQDFEAVVAGCAQSAPGREETWINESIIRLYSQLHDAGYAHSVECWSGADLVGGLYGVSLGAAFFGESMFSLRRDASKVALVHLIARLRAGGYSLLDTQFTTEHLESFGARTISRSDYRERLAEALIFEADFSALPDEITGAQALQSITQTS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_BRUAB
Sequence: MRLEAENLAGERGGETIFSHLSFTIGTGQALVVTGPNGSGKSTLLRIICGLLAPEAGEVKLTEGTQIVPVRAACHYLGHQNAMKPALSVRENLLFWQKFNGGEALDIGAALEAVDLAGVEHLPFGYLSTGQKRRVSIAKLLVSHRPLWIVDEPTAGLDKASEARFAELMREHMRQDGMIIAATHIPLGLDGAISTTGNALVRSLDMAAFSVEDIA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MDTI_ECO27
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LN28A_XENTR
Sequence: MGSVSNQEITGGLPKSLDETADIHKSDESLIFQGSGVCKWFNVRMGFGFLTMTKKEGTDLETPVDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESTRVTGPGGAPCIGSERRPKVKGQQKRRQKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSPNHMVAQCPAKASQAANLEEQPISEEQELIPETME
What is the function of this protein?
RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism.  Seems to recognize a common structural G-quartet (G4) feature in its miRNA and mRNA targets (By similarity).  'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis.  Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization.  Suppressor of microRNA (miRNA) biogenesis, including that of let-7.  Binds specific target miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in their terminal loop, and recruits uridylyltransferase.  This results in the terminal uridylation of target pre-miRNAs.  Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation (By similarity).  Localized to the periendoplasmic reticulum area, binds to a large number of spliced mRNAs and inhibits the translation of mRNAs destined for the ER, reducing the synthesis of transmembrane proteins, ER or Golgi lumen proteins, and secretory proteins.  Binds to and enhances the translation of mRNAs for several metabolic enzymes, increasing glycolysis and oxidative phosphorylation.  Which, with the let-7 repression may enhance tissue repair in adult tissue (By similarity).
What are the official names of this protein?
Protein lin-28 homolog A, Lin-28A.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Cytoplasm. Rough endoplasmic reticulum. Cytoplasm, P-body. Cytoplasm, Stress granule. Nucleus, nucleolus. Note=Predominantly cytoplasmic. In the cytoplasm, localizes to peri-endoplasmic reticulum regions and may be bound to the cytosolic surface of rough endoplasmic reticulum (ER) on which ER-associated mRNAs are translated. Shuttle from the nucleus to the cytoplasm requires RNA-binding.
Protein: RL7_THET2
Sequence: MALDIERIKEELSQATVLELKQLIDALKEAWGVTAAAPVAVAAAPAAGAAAAPAEEKTEFDVILKEAGAKKLEVIKELRAITGLGLKEAKDLAEKGGPVKEGVSKQEAEEIKKKLEAVGAVVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: IBP2_HUMAN
Sequence: MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ
What is the function of this protein?
Inhibits IGF-mediated growth and developmental rates.  IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 2, IBP-2, IGF-binding protein 2, IGFBP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: F221B_MOUSE
Sequence: MEANKTTEGPQDTQDAKEQPSLEDTNAEDLYEATTHETPLQPSSSQKHFQPPEIHLETPASLNPDTKGAEGLQDSSVSGTPPVKSSSSGLLSLPPQLSPQSVTSLEKAIAEIPLEEFGYDSPISKVKEEPLQLSPTANIPEYGSPISEVQKESLEVSPTANIPEYGSPISEVQKEPLEVSSTANIPKYESPVSEVQKEPLEVSPTASIPESSHELTSDKVPQTQVPESEHFPKHSFSESPTQAKEDESTKEGEAGEDELAVGTSKIPAAKPGLRAKKKKEKRAGGVTSRPVVPAKRAELVEMAKAVHREQFDDQVNNLFQWEKDSTLKAIQTGIYIGWRCPHYLWDCFRIGDESKCFCGHLLREHQIISDLSVPCSVSQCRCLMFCFIPSRPEEVGEFWLKKRATFDPKAWRAQCRCKHTHEEHAATGAHPCRHRGCFCPSFESNFLCVACDRRWEEHETFFETGDTRRKGKRPYGANNIKNWHRTY
What are the official names of this protein?
Protein FAM221B.
What is the protein family that this protein belongs to?
Belongs to the FAM221 family.