PharMolix/UniProtQA huggingface dataset:
Protein: HLS1_ARATH
Sequence: MTVVREYDPTRDLVGVEDVERRCEVGPSGKLSLFTDLLGDPICRIRHSPSYLMLVAEMGTEKKEIVGMIRGCIKTVTCGQKLDLNHKSQNDVVKPLYTKLAYVLGLRVSPFHRRQGIGFKLVKMMEEWFRQNGAEYSYIATENDNQASVNLFTGKCGYSEFRTPSILVNPVYAHRVNVSRRVTVIKLEPVDAETLYRIRFSTTEFFPRDIDSVLNNKLSLGTFVAVPRGSCYGSGSGSWPGSAKFLEYPPESWAVLSVWNCKDSFLLEVRGASRLRRVVAKTTRVVDKTLPFLKLPSIPSVFEPFGLHFMYGIGGEGPRAVKMVKSLCAHAHNLAKAGGCGVVAAEVAGEDPLRRGIPHWKVLSCDEDLWCIKRLGDDYSDGVVGDWTKSPPGVSIFVDPREF
What is the function of this protein?
Ethylene-responsive N-acetyltransferase required for differential cell elongation in the hypocotyl.  Regulates apical hook formation of dark-grown seedlings.  May control differential cell growth by regulating auxin activity.  May be involved in negative feedback regulation of auxin homeostasis through the control of GH3-like genes.  Modulates de novo shoot organogenesis.
What are the official names of this protein?
Probable N-acetyltransferase HLS1, Protein CONSTITUTIVE PHOTOMORPHOGENIC 3, Protein HOOKLESS 1, Protein UNUSUAL SUGAR RESPONSE 2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: MURB_RICAH
Sequence: MLILPTVKGEYQKDYNLKHLTWFKVGGDAEIFFKPLDSEDLASFLIQNRQKLPITTFGAGSNIIIRDGGIEGVVIKLGQNFSNIEFIDNHLIVGSSCLNYNLAKFCQANDISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIIVRIEAIDFAGNFRTFTNAESGFKYRGNNLPKDLIILKAVFKVNKGDSENILLRMNEINNTRSLTQPIKERTGGSTFANPEGLKSWELIDKAGLRGYRIGGASMSELHCNFMINNGDATSKDLEDLGDFVRQKVFEDSGVELKWEIKIIGKYV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPB_SALHS
Sequence: MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAENMEVSGATFTNGLLHIDLTRNEPETIAPQRIAINERSALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP1_PHONI
Sequence: QKKDKKD
What are the official names of this protein?
Tachykinin-like peptide-I, P.nigriventer tachykinin peptides I, PnTkP-I, U29-ctenitoxin-Pn1a, U29-CNTX-Pn1a.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_STAAW
Sequence: MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: Y1520_METJA
Sequence: MNRNDYDVVIIGGGPVGCITGEYIKNGRVLIVEEHQSIGVPLQCAGLISKNGVKELGNPKGVVNKVRGAYIYSKNSMVKIGNEGIRAYIFERKVMDKDIAIRAAKKCDFLLKAYGKIEKDKNGYKVEITHLGEKITLNPKIIVGADGAKTITGKKLGLVNNKNREILSSCQFEMVNAEVDDDFVYIFLDRKYSERFFTWIIPMGKDRVRVGLIDRGNCYNKLIRFINENKIAKEILKNATITEFSTGSLPIGYLDKTFKDNVLLVGDAACHVKPLSGGGLYFGAMGGKIAGEVISKYLNEDIENLELYDKRWKETFGSEIKNGLRVRKLFLKLGNDTLDKIIEKLSKSDLIDYINKHGDMDRQASLSIKVLKSLDIGLGFRILRDLL
What are the official names of this protein?
Uncharacterized protein MJ1520.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. ChlP subfamily.
Protein: RL5_DESVM
Sequence: MTRLEQIYREKVVPVLQKEFNYTSSMQVPGIEKVSLNIGLGAASQNNKLMEEAIKELTAIAGQKAVVTRAKKSIASFKLREGMPIGCRVTLRKERMWDFLDKLMNFALPRVRDFRGIPDRGFDGRGNFTLGIKEHTIFPELEVDRVDNPKGMNITIVTTAQTDKEGKLLLDQLGMPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PDRP_SINMW
Sequence: MENRKNYFHLHLISDSTGETLIAAGRAAAAQFQSSHALEHVYPLIRNRKQLMQVMEAVDGAPGIVLYTIVDRELAGLIDQRCREIGVPCVSVLDPIIELFQSYLGSPSRRRSGAQHVMDAEYFARIEALNFTMDHDDGQIPADFDEADVVLVGVSRTSKTPTSIYLANRGIKTANIPIVPGVSLPEGLLTATKPLIVGLIASAERLSQVRQHRVLGTTQSFHGEDYTDRAAIAEELKYARSLCARNNWPLIDVTRRSIEETAAAIVALRPRLR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: MURA_DEIDV
Sequence: MQLTPLHIQGGRELRGEIAVQGSKNAALPIIVASLLSSEKVTLHGIPRLSDVYTILDLVHHIGTQHQWVGPNSLELHTPSIVNTDAPYALVNKMRASFVVLGAILARAGQARVSMPGGCAWGPRPVDQHVKALRALGAEISEEGGNFHARRQGSLNGTFVFELLTVGGTHNAVLAAVLGDGVVTLENASIDTDVVDLIEFLNSLGADIQGAGTNTLVIRGVQQLRGGEYTVIPDRIEAGTFMMLAAATRSQLTVRNVRPDHLRAVSAKLQEMGVDILEAGNSLIVDARQRELRPVNVTTQSYPGFPTDVQPQMSALLATVPGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGSALHAAPVKAADLRAGAALFIAGLTCTGETVIDGVQYLNRGYENLAERLCGIGATAQQTELAVAMD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BACAC
Sequence: MPTINQLVRNGRTDKVWKSKSPALNKGFNSLKKKSTDISAPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDKRMQGRSKYGTKKPKAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ATPL_CERS4
Sequence: MEGDIAEMGKFIGAGLATIGLGGAGIGVGHVAGNFLAGALRNPSAAPGQMANLFVGIAFAEALGIFSFLIALLLMFAV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESPD_MYCTU
Sequence: MDLPGNDFDSNDFDAVDLWGADGAEGWTADPIIGVGSAATPDTGPDLDNAHGQAETDTEQEIALFTVTNPPRTVSVSTLMDGRIDHVELSARVAWMSESQLASEILVIADLARQKAQSAQYAFILDRMSQQVDADEHRVALLRKTVGETWGLPSPEEAAAAEAEVFATRYSDDCPAPDDESDPW
What is the function of this protein?
Required for ESX-1 function (PubMed:16135231, PubMed:22155774).  Required for the maintenance of adequate cellular levels of both EspA and EspC (PubMed:22155774).  Facilitates EsxA secretion (PubMed:22155774).
What are the official names of this protein?
ESX-1 secretion-associated protein EspD.
What are the subcellular locations of this protein?
Secreted. Note=Export does not exclusively require ESX-1. May require one (or more) of the other ESX / type VII secretion systems (T7SS).
Protein: PSB_STRRD
Sequence: MGSHRDLPAGMVNHIFTNSGISSFTEFVGSYAPDLLPGRNETLAAPVGDRIPHATTIVAATCAGGVVMAGDRRATSGNIISQRDMEKVFRTDDYSCMGIAGTASTGIEMARLYRVELEHYEKMEGRTLSVAGKANRLATMIRGNLGMAMQGLVVVPLFAAYDPEIDGGRIFGYDVGGGPYEQQQYHSIGSGSIFARGSLKKLYRENASPEEVVLTLIHALYDAADDDSATGGPDVTRKIWPVVAQITADGFHRLSDEEVGGHVQTVLQERMSSPDGPVAPLR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FHBP_NEIMH
Sequence: MNRTAFCCLSLTTALILTACSSGGGGVAADIGAGLADALTAPLDHKDKGLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIEVDGQLITLESGEFQVYKQSHSALTAFQTEQIQDSEHSGKMVAKRQFRIGDIAGEHTSFDKLPEGGRATYRGTAFGSDDAGGKLTYTIDFAAKQGNGKIEHLKSPELNVDLAAADIKPDGKRHAVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVNGIRHIGLAAKQ
What is the function of this protein?
A bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH) (PubMed:16785547).  Binding contributes to the avoidance of complement-mediated lysis by N. meningitidis (Probable).
What are the official names of this protein?
Factor H binding protein, fHbp, Genome-derived Neisseria antigen 1870, GNA1870, Lipoprotein 2086, LP2086.
What is the protein family that this protein belongs to?
Belongs to the factor H binding-protein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Surface exposed.
Protein: FES1_PHANO
Sequence: MNDPQLNNLLKWGIQNSDASRNDPSTAPQPLSEVDKEALQQLIAGVRGPSDADLMQDSFQVIENNEATAEAKHQAFENFEQLIQGIDNANNMEALGLWTKLIKQLESEDPVIRKWAAWCCSTAVQNNVRSQERLLVLKNAIPTLVRLATSDPDKTARKKATSALSSAVRNFQPGLDAVLEHMPAEHKPKEALDANDMASVDILINKLRESI
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBX_PROM0
Sequence: MLQISNLLLAADFSAEVANNSAVGMIGSFIAAALLIVIPATAFLIFVSQKDSLDRTSTGRR
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: NTF2_ARATH
Sequence: MAQQEASPSPGAEVVGRAFVEQYYHILHQSPGLVHRFYQDSSFLTRPDVTGAVTTVTTMQAINDKILSLKYEDYTAEIETADAQESHERGVIVLVTGRLTGNDNVRKKFSQSFFLAPQDKGYFVLNDVFRFLEEKEVTAQARSVPINGTTRDVQAPIEPERVVVSHEPEVEPEPVASIEEEDLDNVAEVYDPSDKDEGVVVDVEPIEPPTQISHNEILSVPQGDAPKHSYASILKQMKSSPAPTTHVARNKPRPAPVNQKLTAPPAEPAARPEASAHENVPNSSHVDVEDDGHSIYVRNLPFDSTPTQLEEVFKNFGAIKHEGIQVRSNKQQGFCFGFVEFETSSGKQSALEASPVTIGDRQAVVEEKKTNSRGGGNNGGSRGRYFSGRGSFRNESFKGGRGGGGRGGYGRGGGEFSGRPKSSNPRNGGEGYQRVPQNGGGGRGGRGEGGRGGARGGGSS
What is the function of this protein?
Involved in RNA-directed DNA methylation (RdDM).
What are the official names of this protein?
Nuclear transport factor 2, AtNTF2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GATC_RALSO
Sequence: MALELSDVKRIAHLARIEVSDGEAAQTLTQLNQFFTLVEQMQAVDTTGIEPMAHPIEQVQAPAQRLREDAVTEPDRRADYQQCAPSTEAGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CA198_DANRE
Sequence: MAAAAMAGAADPPHLTEAKKLEYFSSINSMARKIMQEREKIKETYGSAWSQMSPVEQDTAIDNGMMDPRIRARYAMHRVDRDEVICYPKLLIQTGQKIVHFGEEDLTWQDEHSAPFSWETKSQMDFSISNMTELFVPPSVNEPKPKTSQTTKPPSNDESSFWKISAERSRLDNEKAEFPSLTPSQIKSLEKGEKPLPSYLRLESGSRDMEEVPVSRPAKQRAPKPPAPPPPPPVPISMTPAAISVTPTPPAPVPSLEEGWERAQSTLPSVSSTTDEVFSPGLVTRSSSQSNSTVKDVEKAEASPASSPTFSQFNTSSSILKTGFDFLDNW
What are the official names of this protein?
Uncharacterized protein C1orf198 homolog.
Protein: PTGCB_ECOLI
Sequence: MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLHLPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLAAIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPFQMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPENRAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDGTSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATEDAKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDEYIRNH
What is the function of this protein?
(Microbial infection) Probably transports the toxic C-terminal region of CdiA from E. coli strains NC101 and 3006 across the inner membrane to the cytoplasm, where CdiA degrades specific tRNAs.  Toxin transport is strain-specific, mutations in this gene do not confer resistance to several other tested CdiA toxins (PubMed:26305955).  Probably also serves as the inner membrane receptor for CdiA-STECO31 from E. coli strain STEC_O31 (Probable).
What are the official names of this protein?
PTS system glucose-specific EIICB component, EIICB-Glc, EII-Glc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GASP3_RAT
Sequence: MTGSKNKARAQAKLEKRASAQAKAAAEREAANAGRGAGKNRDKGKGKAGSKTDAVAEAKAGSKSKVVAETKEGARPESKAVAKGTSDFNHKAENKYARSARKDKPSSDSWFWAGEDSGINSWFWKGEEVSNNSVAKCENKPSTSIQARVEEHTPRTSHKSRSGAEEEEEENVIGNWFWEGDDTGFDSDPKPVFKIVKPQPVDEINEKDRPKDWSEVTIWPKAPAVTPAVLGYRSQDSSEGRPSSYIVLASNEEETSTTCTKNTRSSLQPIPEYPFGSDPCIQTLDEIRQQIKIREENGIKPFACPCKMECYLDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIKKAVITLNSSGDDRQQMVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKAARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGSIVVVDHLSYNTLTAIFREVKGIIERM
What is the function of this protein?
Survival and differentiation promoting protein that plays a role in the regulation of neurosynaptogenesis.  Induces phosphatase PP2A activity which results in APP dephosphorylation and inhibits BACE1-mediated processing of APP.
What are the official names of this protein?
G protein-coupled receptor associated sorting protein 3, Protein BHLHb9, bHLHb9, Transcription regulator of 60 kDa, p60TRP.
What is the protein family that this protein belongs to?
Belongs to the GPRASP family.
Protein: RL19_PETMO
Sequence: MDKIINAVETNYKKEDIPEIRPGDTVRVNVKVVEGEGEKKRERIQPFEGIVIKIRGAGLGRSFTVRKMGADRVGVERIFPFHSPSISSIEVLKKGKTRRAKLYYLRDVKGKIRIKERKD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PPAT_STAAC
Sequence: MVQSLHEFLEENINYLKENGLYNEIDTIEGANGPEIKINGKSYINLSSNNYLGLATNEDLKSAAKAAIDTHGVGAGAVRTINGTLDLHDELEETLAKFKGTEAAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDGCRLSKAKIIRVNHSDMDDLRAKAKEAVESGQYNKVMYITDGVFSMDGDVAKLPEIVEIAEEFGLLTYVDDAHGSGVMGKGAGTVKHFGLQDKIDFQIGTLSKAIGVVGGYVAGTKELIDWLKAQSRPFLFSTSLAPGDTKAITEAVKKLMDSTELHDKLWNNAQYLKNGLSKLGYDTGESETPITPVIIGDEKTTQEFSKRLKDEGVYVKSIVFPTVPRGTGRVRNMPTAAHTKDMLDEAIAAYEKVGKEMKLI
What are the official names of this protein?
Putative pyridoxal phosphate-dependent acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: BOK_RAT
Sequence: MEVLRRSSVFAAEIMDAFDRSPTDKELVAQAKALGREYVHARLLRAGLSWSAPERASPAPGGRLAEVCTVLLRLGDELEQIRPSVYRNVARQLHIPLQSEPVVTDAFLAVAGHIFSAGITWGKVVSLYSVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRGGWTDVLKCVVSTDPGFRSHWLVATLCSFGRFLKAAFFLLLPER
What is the function of this protein?
Positively regulates apoptotic process in an heterodimerization-independent manner with antiapoptotic Bcl-2 proteins.
What are the official names of this protein?
Bcl-2-related ovarian killer protein.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion inner membrane. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane. Early endosome membrane. Recycling endosome membrane. Nucleus outer membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Membrane. Note=Nuclear and cytoplasmic compartments in the early stages of apoptosis and during apoptosis it associates with mitochondria. In healthy cells, associates loosely with the membrane in a hit-and-run mode. The insertion and accumulation on membranes is enhanced through the activity of death signals, resulting in the integration of the membrane-bound protein into the membrane (By similarity). The transmembrane domain controls subcellular localization; constitutes a tail-anchor. Localizes in early and late endosome upon blocking of apoptosis. Must localize to the mitochondria to induce mitochondrial outer membrane permeabilization and apoptosis (By similarity).
Protein: UBE2A_HUMAN
Sequence: MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.  In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination.  Required for postreplication repair of UV-damaged DNA.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 A, E2 ubiquitin-conjugating enzyme A, RAD6 homolog A, HR6A, hHR6A, Ubiquitin carrier protein A, Ubiquitin-protein ligase A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: MP35_DICDI
Sequence: MQNKKIAHIVRIEMFEEKIDRLDLIFTKYVEYKFPLYLLGKLWLYKFIRRKFNLIGPLNEQILSPYLQFNLYFDKSKARKETFKVYLGKIGFVLLHVFYLSCIAYYDSFLYAKVMNDWLEEVMRTRY
What are the official names of this protein?
Uncharacterized mitochondrial protein 35, ORF127, Ribosomal protein S11.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RCII_BPP4
Sequence: MAELLREQEVKIALIEWLYKKGMLSDATIINEMVVANWSRRADLAIANGSLQAFEIKSDFDSLKRLDGQLKIFKSSFEKVTIVCAPKFTSEVSKRVSSDVGVVEFQSNNSSVRFKIIQKGRVCSRLNKFVYLGFLLKSELKDLLNQYGITFSNELHRDCLEVLASKLSLNKIREFVITSIKNRYHATSNDFLSRLHGNQEISINDLALLSKAKRRNNSLVKFEFKACSEKSLNEYHKVDVDSIVRKYGDDVSYIPEKVLKRVVG
What is the function of this protein?
Mutations in this gene cause a clear-plaque phenotype as a result of efficient killing of infected cells by P4.  How this comes about is not understood.
What are the official names of this protein?
Protein cII.
Protein: MSCL_GEOTN
Sequence: MWNEFKKFAIRGNVIDLAVGVIIGGAFGKIVSSLVNDIIMPLVGLLLGGIDFSNLSWKVGKAVVKYGAFIQTVVDFLIIAFSIFLFVKLINKLYERVKKQEEMEETEPTLTKEEELLTEIRDLLKQQRETM
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UN45B_XENLA
Sequence: MEDPVQLKEEGNKYFQSNDYGNAIECYSKALKLITDKKMKAVLYRNRSACYLKQENYIQAAADASKAIDVDASDIKALFRRCQALEKLGKLDQAYKDVQRCATLEPKNRTFLEMLHRLGSNIQEKLHVQFSTDSRVQKMFEILLDENSDKEKREKAANNLIVLGREDAGAERIFQNNGVNLLMQLIETKDPELILSAVRTLSGMCTGHRARATAIVHLVGINKICSIMAVDHEEIALAACNLLQNIVDSLTGEDKKVHGKEEALVLDTKKDLKVITTHLLDMLVSKKVSGHGRDQALNLLNKNIPRYDLKNKDNSKTLFVVDVGLKKILKVLGQVPELPNCLPLTPNTRLNASVLINKLYDDLRCDPERDDFRKICEEYITGSFDPKDMEKNLHAIQTVSGILQGPFDLGNILLGMQGVMEMMVALTGSEKEVDQLVAVEALIHASTKLSRASFIITNGVSLLKDIYKKTKNEKIKIRALVGLCKLGSAGGTDYALRQFAEGSTDKLAKQCRKWLCNTSLDIQTRKWAVEGLAYLTLDADVKDEFVEDEQSLKAMFELCKTSDKTILYSVATTLVNCTNSYDVKEVIPEMVQLAKFSKQHVPEQHPKDKKDFVLKRVKKLLQADVISALSCMVKADNSILTDQTKEQIARVFLALCDEPKDRGIIVAQGGGKAMIPLALEGTDVGKTKASHGLAKIAAVSNPDIAFPGERVYEVVRPLVSLLNTERDGVQNFEALLALTNLSGKSDKLRQKIVKEKALPEIENYMFENHEQIRQAATECMCNLAVNKEVKERFTAEGNDRLKLIVLLCGEDEEVKLQRAAAGTLAILTAAEKKLCHKMTEVTSQWLEILQRLCLNEDLQVQHRGVVITYNLISAEKELAKKLVESEMLEILTVIGKQADVPNKQHIINVAREALVKCLDYGFIKTVS
What is the function of this protein?
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain.  Plays a role in sarcomere formation during muscle cell assembly (By similarity).  Is necessary for normal early lens development.
What are the official names of this protein?
Protein unc-45 homolog B, Unc-45B.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, perinuclear region. Cytoplasm, cytosol. Note=Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage.
Protein: ENOPH_DROPE
Sequence: MPSTERVAKVVLVDIEGTTTSISFVHDVLFPYAKNNVQKFLEESWESSSEVKQIVRELQQVPQYAEYTATLRVPPKEVDVQVITGFVRYLIDKDLKVTPLKTLQGLIWQQGYETGELMGHVFNDVPGAFEAWREAGLRIAVYSSGSVAAQKLIFRYSIVGDLLTHLSAHFDTHVGHKQESQSYANIAQSLGEDPSHILFLTDIPGEAAAARSAGLQTIILQRPGNTPLTDDQKYSNELIADFSSLHTLQLPE
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.