PharMolix/UniProtQA huggingface dataset:
Protein: RS3_RHOOB
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRKLLATGMERAGIAKVEIERTRDRVRVDIHTARPGIVIGRRGAEADRIRSELEKLTGKQVQLNILEVKNAEAEAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAANVAAPAGDRPRRERPSRPRRSGATGTTATSTEAGRAATATADAPATTEQKEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SARAF_BOVIN
Sequence: MAAAGGPAAAGRCALSSLLLLLLVVGTAQCWDERDRILLRDIKALTLYYDRYTTSRRLEPIPQLKCVGGTAGCDSYTPKVIQCQNRGWDGYDVQWECKTDLDVAYKFGKTVVSCEGYESSEDQYVLRGSCGLEYQLDYTELGLKKLRESGKEHGFNSFSNYYSKLYSPESSSLGGVVTIVVLLAIAFGVYKFFLSDGHESPPPYSEDPPYSHRYQRFSSSAGPPPAGFKSEFTGPHGATAGFGSAFTGQQGHEHSGPGFWTGLGTGGILGYLFGSNRAATPFSDSWYPSYPPSYTSTWNSRAYSPLRGGPGSSSACSGSEPRTRTASGYGGTRRR
What is the function of this protein?
Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling.  In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions (By similarity).
What are the official names of this protein?
Store-operated calcium entry-associated regulatory factor, SARAF, SOCE-associated regulatory factor, Transmembrane protein 66.
What is the protein family that this protein belongs to?
Belongs to the SARAF family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Translocates to the endoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1- dependent manner following cytosolic Ca(2+) elevation.
Protein: UPP_ACIB5
Sequence: MAIQEIRHPLIRHKLGLLRRADISTKNFRELAQEVTMLLTYEATKDLPVVDCEIEGWAGNVTTQRIAGKKITIVPILRAGIGMLDGVLNLIPSAKVSVLGLERDEATLEVRTYYKKLVPDVANRIAMIIDPMLATGNSLVAAIDVLKASGCKDIRVMVLVAAPEGIAKVEAAHPDIQLYTASIDNGLNEHGYIVPGLGDAGDKIFGSVQKD
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PP411_ARATH
Sequence: MIKANVYSCSKFRFLYRRRFLSQSSFVHSLDANVSSLIAAVKSCVSIELCRLLHCKVVKSVSYRHGFIGDQLVGCYLRLGHDVCAEKLFDEMPERDLVSWNSLISGYSGRGYLGKCFEVLSRMMISEVGFRPNEVTFLSMISACVYGGSKEEGRCIHGLVMKFGVLEEVKVVNAFINWYGKTGDLTSSCKLFEDLSIKNLVSWNTMIVIHLQNGLAEKGLAYFNMSRRVGHEPDQATFLAVLRSCEDMGVVRLAQGIHGLIMFGGFSGNKCITTALLDLYSKLGRLEDSSTVFHEITSPDSMAWTAMLAAYATHGFGRDAIKHFELMVHYGISPDHVTFTHLLNACSHSGLVEEGKHYFETMSKRYRIDPRLDHYSCMVDLLGRSGLLQDAYGLIKEMPMEPSSGVWGALLGACRVYKDTQLGTKAAERLFELEPRDGRNYVMLSNIYSASGLWKDASRIRNLMKQKGLVRASGCSYIEHGNKIHKFVVGDWSHPESEKIQKKLKEIRKKMKSEMGYKSKTEFVLHDVGEDVKEEMINQHSEKIAMAFGLLVVSPMEPIIIRKNLRICGDCHETAKAISLIEKRRIIIRDSKRFHHFLDGSCSCSDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g40410, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CPG1_PORG3
Sequence: MNKFVSIALCSSLLGGMAFAQQTELGRNPNVRLLESTQQSVTKVQFRMDNLKFTEVQTPKGMAQVPTYTEGVNLSEKGMPTLPILSRSLAVSDTREMKVEVVSSKFIEKKNVLIAPSKGMIMRNEDPKKIPYVYGKSYSQNKFFPGEIATLDDPFILRDVRGQVVNFAPLQYNPVTKTLRIYTEITVAVSETSEQGKNILNKKGTFAGFEDTYKRMFMNYEPGRYTPVEEKQNGRMIVIVAKKYEGDIKDFVDWKNQRGLRTEVKVAEDIASPVTANAIQQFVKQEYEKEGNDLTYVLLVGDHKDIPAKITPGIKSDQVYGQIVGNDHYNEVFIGRFSCESKEDLKTQIDRTIHYERNITTEDKWLGQALCIASAEGGPSADNGESDIQHENVIANLLTQYGYTKIIKCYDPGVTPKNIIDAFNGGISLVNYTGHGSETAWGTSHFGTTHVKQLTNSNQLPFIFDVACVNGDFLFSMPCFAEALMRAQKDGKPTGTVAIIASTINQSWASPMRGQDEMNEILCEKHPNNIKRTFGGVTMNGMFAMVEKYKKDGEKMLDTWTVFGDPSLLVRTLVPTKMQVTAPAQINLTDASVNVSCDYNGAIATISANGKMFGSAVVENGTATINLTGLTNESTLTLTVVGYNKETVIKTINTNGEPNPYQPVSNLTATTQGQKVTLKWDAPSTKTNATTNTARSVDGIRELVLLSVSDAPELLRSGQAEIVLEAHDVWNDGSGYQILLDADHDQYGQVIPSDTHTLWPNCSVPANLFAPFEYTVPENADPSCSPTNMIMDGTASVNIPAGTYDFAIAAPQANAKIWIAGQGPTKEDDYVFEAGKKYHFLMKKMGSGDGTELTISEGGGSDYTYTVYRDGTKIKEGLTATTFEEDGVATGNHEYCVEVKYTAGVSPKVCKDVTVEGSNEFAPVQNLTGSAVGQKVTLKWDAPNGTPNPNPNPNPNPNPGTTTLSESFENGIPASWKTIDADGDGHGWKPGNAPGIAGYNSNGCVYSESFGLGGIGVLTPDNYLITPALDLPNGGKLTFWVCAQDANYASEHYAVYASSTGNDASNFTNALLEETITAKGVRSPEAIRGRIQGTWRQKTVDLPAGTKYVAFRHFQSTDMFYIDLDEVEIKANGKRADFTETFESSTHGEAPAEWTTIDADGDGQGWLCLSSGQLDWLTAHGGTNVVASFSWNGMALNPDNYLISKDVTGATKVKYYYAVNDGFPGDHYAVMISKTGTNAGDFTVVFEETPNGINKGGARFGLSTEANGAKPQSVWIERTVDLPAGTKYVAFRHYNCSDLNYILLDDIQFTMGGSPTPTDYTYTVYRDGTKIKEGLTETTFEEDGVATGNHEYCVEVKYTAGVSPKECVNVTINPTQFNPVKNLKAQPDGGDVVLKWEAPSAKKTEGSREVKRIGDGLFVTIEPANDVRANEAKVVLAADNVWGDNTGYQFLLDADHNTFGSVIPATGPLFTGTASSNLYSANFEYLIPANADPVVTTQNIIVTGQGEVVIPGGVYDYCITNPEPASGKMWIAGDGGNQPARYDDFTFEAGKKYTFTMRRAGMGDGTDMEVEDDSPASYTYTVYRDGTKIKEGLTETTYRDAGMSAQSHEYCVEVKYAAGVSPKVCVDYIPDGVADVTAQKPYTLTVVGKTITVTCQGEAMIYDMNGRRLAAGRNTVVYTAQGGYYAVMVVVDGKSYVEKLAVK
What is the function of this protein?
Thiol protease.  Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA (PubMed:9786913).  Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).
What are the official names of this protein?
Gingipain R1, Arg-gingipain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C25 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CATA_PSEAE
Sequence: MEEKTRLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSAAYGTFTVTHDITPYTRAKIFSQVGKKTDMFLRFSTVAGERGAADAERDIRGFSMRFYTEQGNWDLVGNNTPVFYLRDPLKFPDLNHVVKRDPRTNLRNATFKWDFFSHLPESLHQLTIDFSDRGLPKSYRHIHGFGSHTFSFINANNERFWVKFHFKTQQGIENLTNAEAAEVIAQDRESSQRDLYESIEKGDFPRWKMYVQIMPEKEAATYRYNPFDLTKVWPHGDYPLIEVGFFELNRNPDNYFAEVEQAAFTPANVVPGIGFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAARCPHQVYHRDGGMRVDGNNAHQRVTYEPNSFNQWQEQPDFSEPPLSLEGAADHWNHRVDDDYYSQPAALFHLFTDEQKQRLFANIAEDIRDVPEQIQRRQIGLFLKVDPAYGKGVADALGLKLD
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: RSGA_NITMU
Sequence: MRSPGRPSVTSPPLRGEIVAAFGRHFLVKTADESTLTCVLRGKKSGAACGDWVEIYQTASEQGVIERILPRSALLYRSDLSREKLIAANATQVIIVVAPVPSFSEELINRCLVAAESQQLSVLIVLNKTDLLGPSKVALNGLSLYRELDYTLLPISARNDVKPLLPYLEDNLSVLVGQSGMGKSTIINALVPDAERATGDISPTLDAGRHTTTHARLYHLDRNARIIDSPGIQQFGLQHLSIEAIAWGFREFRPYIGKCKFNNCRHSGEPGCALANAMRESEVSVRRIDLYHKLIASLNTNRIPSSSSRTKIQ
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LITD1_MOUSE
Sequence: MSGVQSKAARLQKERKEKLSADRERKTATSLCLKHSEVPASMMKQFNALMEMQEVMFAEMRETYKNDIKEMLLKRTAPWVKHLEERIGQQEGDAISERPKPGEKVEELSSGTDEDTENLTVRSKKGKQDKAKPLNSSHVLKSSLERGGEALRGEHGRCGESSSLVDWKNANEKPAREASCQSEENRLKAPKESPPEGGAGATLRLAADFSAATLDVGRQWSQVFRLLKEKELEPELQCSVKLAFKCDGEANVFSDLHSLRQFTSRKPFLRELLKDVFPQNEGGRRNELRERLGKTLGDTKHEARRIASDSLSFLFIKEVEVASPEVKTYKEETLDRKNKGTLKKQEGEEEEISETQGEETSEGETSELGEEEGSESEEEEESSESEEEEESSESAEEIGFISLVVDSESEEEVNRKTASQTKKKETFHGLKELAFSYLVWDSKKKKLVRCQEGGAAAASTQRIGMPCLTLYLTSPSESLGAGSDGPKSHSCTKLSALSQVTPLLTNIEKGRYKVPQTEEPTAKEADLILETEENFKRGVISVIRQMQREVDKIKNIYVSDVLNMKSSLDDLNSLACTIEARVSEQEDAVEGLTKDTMQLAREIVDKERLREREDRFRSSNIRVIGIPEKENRENGAVDIIKEVIEENFAELEDQSLEIVSAHRVPNSVDEHRLTPRHILVKFGSASDKQRVLKASRAKQEITYRGSKIRLTADLSPGTIDARSQWCGIIKILQDEGFQPRILYPAKLAFDFKGKTKIFFDIEEFKKFISDIPYLKDLLNNIH
What are the official names of this protein?
LINE-1 type transposase domain-containing protein 1, ES cell-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the transposase 22 family.
Protein: MOAA_SULAC
Sequence: MKDVYGRELEDLRITLTHACNFTCFFCHMEGENDGDSLLSADQISLVAQIGMEFGIRTVKLTGGEPTLRRDLPEIISKLKEVGIKEVSMTTNGYLLKELAGKLKDAGLDRVNISLHSIDPVIFKEVTGVNVLSKVVEGIEEAKKVGLRPLKLNYVVTRKNAKGIFEFINFASSSNIDEIHLIELHPVGLGKEAFYTHVDMSDIEGRLNEDCTLVEIRNKHKRPRYKCGNLVVEVVKPYANPIFCSGCNRIRLTVDGKLKTCLYRDDKIIDISDIIKSSYSTEEKEELLREAYRLAILIREPNFRFRYETSKTG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: FLIE_HELPY
Sequence: MQAIHNDKSLLSPFSELNTDNRTKREESGSTFKEQKGGEFSKLLKQSINELNNTQEQSDKALADMATGQIKDLHQAAIAIGKAETSMKLMLEVRNKAISAYKELLRTQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: YIDZ_ECOL6
Sequence: MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSRELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHEAWNLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSRNPKIVWLRETIKNLYASMA
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: LEXA_CELJU
Sequence: MYNLTSRQEQVLQLIKQYTEETGYPPTRAEIARILGFKSANAAEEHIKALARKGAIEIMPGASRGIRLTESQSGIPIVGRVAAGNPILAQEHIEDYCNIPNSFFSPSADYFLRVHGMSMKDAGILDGDLLAVHRTDQVRNGQIVVARIGEEVTVKRFKRQGNQAQVELWPENPDFKVIHVDMRDQEFSIEGLSVGVIRRD
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CHIT5_LOTJA
Sequence: MIIKLLVALIHYLHETMAVQSIITTPLLVILMSLRSYAFTEPSLHRQQPPSKGGVRAAYWPAWSDFSTSSIDTNYFTHIYYAFVQPAPESFNLEITESYKKWAPKYDGIHNIRPRVTTLLSIGGGGNNATLFSEMASSKQNRASFINSTIHVARKHEFNGLDLDWEWPGDEKDMSNLALLLKEWYKALVVEANTSRKSRLLLTSAVYFNSTISLIGNGPRSYPVRAIRKYLDWASPMCFDYNGAWANETGFNAALYDPNSNISTKYGIGSWIGSGVPAEKLVMGLPLYGRAWELKDPNDHGVGAKAVGPAVDTDGSMDYDEILVFNKDTGAKVVYDEVAVSFYSYSGTTWIGYDDGPSITKKVQFARSMGLKGYFFWAIGKDKDWTISKQASNAWGY
What is the function of this protein?
Possesses chitinase activity in vitro toward glycol chitin, carboxymethyl-chitin, colloidal chitin, and the chitin oligosaccharides (N-acetylglucosamine) (GlcNAc)6 and (GlcNAc)5 (PubMed:27383628).  Hydrolyzes (GlcNAc)6 into (GlcNAc)4 and (GlcNAc)2, or two (GlcNAc)3 molecules (PubMed:27383628).  Has the capacity to inhibit hyphal growth of the fungus Trichoderma viride in an agar-plate bioassay (PubMed:27383628).  Involved in symbiotic signaling (PubMed:30284535).  Required for root hair infection threads (ITs) elongation and nodule development (PubMed:30284535).  Possesses Nod factor (NF) hydrolase activity (PubMed:30284535).  NFs are lipo-chitooligosaccharide signaling molecules produced by nitrogen-fixing rhizobia to initiate nodulation (symbiosis) on the roots of legumes (PubMed:30284535).  Modulates NF levels and signaling to complete transition of infected nodules to functional nitrogen-fixing organs (PubMed:30284535).
What are the official names of this protein?
Class V chitinase CHIT5, LjCHIT5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
Protein: RLMB_CHRVO
Sequence: MSNKRLIHGFHAINARLWQNPKSLIEIWLAGGRHDARAKAVLDKAGAENVKLHIVDKERLDSMSGNARHQGVVAMIDASMNYVDLDDVLENLSEPPLLLILDGVTDPHNLGACLRVADAMGAHAVIAPKDRSATLNATVSKVACGAAEVVPYITVTNLARTLRDLKDAGVWIAGTTMEADTDLYHFDASGPLAWVMGAEGEGMRRLTREHCDVLVSIPMFGTVESLNVSVSSGMVLSESRRQRVLKAG
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC4_CULQU
Sequence: MIRIPFHLRQTPGRTLHSLVRSFASTKPADLSGTQEKSTRQKINFHELKHPSKVPQRPHKSTIDGQSTPTRIPVDAQKGQLLERLSLVDLDSAEAHRTLEDAIEFASQILSVDTDDVEPLYTVLERERLTLREDRVSDGNIQQDVLRNARVTEEENFVAPPENIPLEQEPRK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C-4, mitochondrial, Glu-AdT subunit C-4.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DYS5_LIMSA
Sequence: GLISNLGI
What are the official names of this protein?
Dynastin-5.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_MOOTA
Sequence: MALVLMVVGLGNPGPRYATTRHNAGFMVVDLLADDLGITLDRTREQALTGQGLVGNNRVLLVKPQTYMNNSGQAVAPLARWYGIAPEAILVIHDDLDLAPGRLRLRRGGSSGGHRGLQSIITHLGTTAVPRLKIGIGRPPLGQNVIDYVLKPFSEGDWELIRPVLLEAARAARFLLEGGSMDEAMNRFNH
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE2_STRR6
Sequence: MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNLTTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGPEKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPVVAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLKKLHNILS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase 2, TP synthase 2, TPS 2, Thiamine-phosphate pyrophosphorylase 2, TMP pyrophosphorylase 2, TMP-PPase 2.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL7_ECOL5
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: F16PA_CAMC1
Sequence: MQELNQIFNTIKDIAKEISEVIKYADLGYTTHENATGDTQLKLDVKSDEIITAKFKQLSCVKALISEEKEDELEINKNAKFIIAYDPLDGSSLVDVNFAVGSIFGIYEDEVKPENLIAAAYSIYGPRLELVIAEKKGALPKFYRLGKDGEFKFVKELELKEKGKLNATGATQKGWSQTHRNFINELFNEGYRLRYSGAMVSDLHQILLKGGGLFSYPATSDHPNGKLRVVFEVLPFAFIYENAKGATTDGKNQTLFDIKIEKIHQTTPCFFGSRDEISLLHKFYEQK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP5_ROTGA
Sequence: MAEASEFNFTIKRKQRTMSDRRTREDTKQKKIEEKSDIDLVDSASVYSQESSRSNYSDAYDKLKREPMVEESNDAKYRNFEFSEDEEVHRPSSKASDKSYREMKRKHDDINTSDSILEKLSELNLEIEKIKQMNQPITIDAAFNMILRNVDNLTIRQKQALINAIVNSMN
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: DCE1_PONAB
Sequence: MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
What are the official names of this protein?
Glutamate decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: UPPP_SYNWW
Sequence: MTLFQAFILGAVQGLTEFLPVSSSGHLVIFQHIFAIEEPPLTFDVLVHLGTLIAVFVAFWDDIWGILKKPFCRLTYLLIVGCIPAGLAGFLLAPYFEKAFESLLVVGIALIFTGILLSLSENLSKKHFGLKEADETGFSDAIFIGILQALAIIPGLSRSGSTIAAGLIAGLDREFAARFSFLLSIPVIIGAAIFELSDVFVTGIAANNILPYILGPLTAAIFGFFAIKVVLGLVRRGKLSYFSYYCWIVAAITLFWYNLG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYC35_DESAC
Sequence: IGAGVGRDGTIAATKGKAKTLAELIXMYDS
What is the function of this protein?
Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin.
What are the official names of this protein?
Cytochrome c3, 50 kDa.
What are the subcellular locations of this protein?
Periplasm.
Protein: PLXB3_RAT
Sequence: MLTDFLQAPVMAPWSPFSLHLLLLFLLLLPLTRAHRFSVPNASFNHLVLAPDQGKLYVGAVNHLFQLSPELEMESVAITGPVIDSPDCVPFRDLAECPQAQLTDNANQLLLVSSRAQELVACGQVRQGVCEKRRLGDVTQVLYQAEDPGDGQFVAANTLGVTTVGLVVPLPGRDLLLVARGLAGKLSAGVPPLTVRQLAGPQPFSSEGLGRLVVGDFSDYNNSYVGAFSDAHSAYFVFRRRGARAQTEYRSYVARVCLGDVNLYSYVEVPLTCHGQGLIQAAFLAPDTLLGAFSAGTSQAQAALCAFPLADLDGSMEQARRLCYTTGGQGPNGMEEATVEYGVTSRCVTLPPDSPESYPCGDEHTPSPIAGRQPLEAQPLLQLGQPISAVAALQTDGHTIAFLGDTEGQLHKVFLNSSHGQVYHSQQVGPPGSAISPDLLVDNSGDYLYVLTAQQVDRILVAACPQFPNCTTCLQARDPLCGWCILQGRCTRRAECGRAVQPNQWLWSYEDNHCLHIQSLLPAQHPRQEHGQITLSVPGLPNLAMDEYFYCAFGDYNSLAQVEEHHVVCATPPQDRMPPNPPGSDHVTLPLALMFEDVVLAATTFSFYDCSAIQALEVAAPCRTCVSSLWRCHWCPQSSHCVYGERCPEGEKAVYSAQEVDILVRGPEACPQVKGLASPQLVPVGWESHVTLHIENLHYFRGLPALYYCWLELPGKLRKLPAFLEETSRNSGLIHCQAQQFHPSMSQWELPVPIYVTRGEIQRLDNTGDLHVTLYDCAMGHPDCSHCQAANGSLSCLWCGDGQPACRYGPLCPPGAVEQLCPIPSIDVIEPLTGPPEGGLAITILGSNLGQAFNDVRNAVTVAGQPCNPDPSLYRISARIVCVTSPAPNGTSGPVQVAIKSRPPGISAQHFTYQDPVLLSLNPQWGPQAGGTQLTIHGQYLQTGGNVSAFVGDQPCPIQEPVCPEAIICHTMPQMEPGEAVVFVVFGHVERKLLTTPFRYTANPQLVEAEPSVSFRGGGRVIRVRGTGLDVVWQPLLSVWLEDEFQVKALGVQAQDVNPRRSCGAPAADPQACIHLESGLLQCSTLCSVNSSSLLLCHSPAVPDGALPKRVFFALDNMQVDFASASGGQGFLYQPNPRLAPLSHEGITHPYRLKPGHVLDVEGEGLNLGISKEEVQVHIGDGKCLVKTLTLTHLYCEPPQQAPQPTNGSGTLPQFVVQMGNVRLALGPVQYEAEPMISTFPVEAQVGLGMGAAMLIAAVLLLTLMYRHKSKQALRDYQKVLVQLENLETGVGDQCRKEFTDLMTEMTDLTSDLEASGIPFLDYRTYAERAFFPGHVGCPLQPGLEGPGEEGRRVTVCQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHSKLEYLTDIMRTLLGDLAAHYVHKNPKLMLRRTETMVEKLLTNWLSICLYAFLKEVAGEPLYMLFRAIKYQVDKGPVDAVTGKAKRTLNDSHLLREDVEFRPLTLMALVGPGAGGAAGNSEVHRVPARVLDTDTITQVKEKVLDQIYKGTPFSQRPSVHSLDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVVLIPQLHNGGTVSQSLEQTGCHSGENTPMLEDGEEGGVRLWHLVKATEETEGAKVRRSSLRERERERARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSMNRPVPIAVKYLFDFLDELAEKHGIEDPETLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNEDAILAVIAQTFIDSCMVSEHKVGRDSPVNKLLYAREIPRYKQMVEKYYADIRQSSPASYQEMNSALAELSGNYTSAPNCLEALRELYNHIHRYYDQIISALEEDPVAQKMQLACRLQQVAALVEYKVTDL
What is the function of this protein?
Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration.  Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation.  In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.
What are the official names of this protein?
Plexin-B3, Protein Plxnb3.
What is the protein family that this protein belongs to?
Belongs to the plexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with RIT2/RIN at the plasma membrane.
Protein: RLME_ACTP2
Sequence: MGRKRSASSSRWLAEHFKDQFVQKAHKQKLRSRAYFKLDEIQQTDRLFKPGMTVVDLGAAPGGWSQYAVTQIGSKGRIIACDILDMNPIVGVDFLQGDFREESVLNALLERVGDDMVDVVMSDMAPNFSGMPSVDIPRAMYLVELALDMCRQVLAPKGSFVVKVFQGEGFDDYLRDIRAMFTTVKVRKPEASRDRSREVYIVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.