PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_PECAS
Sequence: MTLLALGINHKTAPVSLRERVVFSQDKLGVALDSLLQQPLVQGGVVLSTCNRTELYLSVDEQENQREQLIRWLCEYHQLRPEEVNSSLYWHQGNAAVSHLMRVASGLDSLVLGEPQILGQVKKAFAESQRGHSLSSELERLFQKSFTVAKRVRTETDIGASAVSVAFAACTLARQIFESLADVTVLLVGAGETIELVARYLRDHNVQKMVIANRTRERAQALATEVGAEVITLAELDEQLVHADIVISSTASTLPIIGKGMMERTLKARRNQPMLMVDIAVPRDIEPEVGKLPNVYLYSVDDLHAIIQHNLAQRKAAAVQAESIVQQESSDFMAWLRAQSAVETIRDYRAQADELRAEMTAKALAAIQQGNDVEAVIQELTHRLTNRLIHAPTKSLQQAARDGDQNRLQILRDSLGLD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: FUR_BORPA
Sequence: MSDQSELKNMGLKATFPRLKILDIFRKSDLRHLSAEDVYRALIAENVEIGLATVYRVLTQFEQAGILTRSQFDTGKAVFELNDGDHHDHLICTNCGTVFEFSDPDIEKRQYKVAKDNGFVLESHAMVLYGICGNCQKGR
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_ORITB
Sequence: MARFPITIKGFHKLEQELKHLKYVERLKITTDISTAREFGDLSENAEYKAAKERQLLNDKKIYDLENKLANAEVIEITKINSNSVKFGARVVLLDLDTEKEVVYQIVGEYEADITQNLISIASPIAQALIGKKAGDIIEVITPKGGRFYELLKVQYVDF
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: GLYA_SYNR3
Sequence: MRSPQALLQGDPEIAGLINKELERQQSHLELIASENFASPAVMAAQGSVLTNKYAEGLPNRRYYGGCEHVDAIEELAIERAKQLFGAAWANVQPHSGAQANFAVFLALLKPGDTILGMDLSHGGHLTHGSPVNVSGKWFKAVHYGVDPETQQLNLESIRQLALEHKPKLIVCGYSAYPRSIDFAGFRAIADEVGAYLLADMAHIAGLVAAGVHPSPVPHCHVVTTTTHKTLRGPRGGLILCNDADFAKQFDKAVFPGTQGGPLEHVVAAKAVAFGEALQPSFKQYSQQVVANAQALAERLQERGIAVVSGGTDNHVVLLDLRGIGMTGKVADLLVSEVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDEAAFSEVADVIADRLLNPEDAAIEQRCRDRVASLCQRHPLYGPASPVLAA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_PETMA
Sequence: MASTKGKLIHEMVPSKERDPPHSKVTIVGVGQVGMAAAISVLLRDLADELALVDVVEDRLKGEMMDLLHGSLFLKTAKIVADKDYSVTAGSRLVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILLVVSNPVDILTYVAWKLSGLPKHRVIGSGCNLDSARFRYLMSERLGVNSASCHGWIIGEHGDSSVPVWSGVNVAGVGLQSLNPDIGTPKDGEDWKSVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAETILKNLRRVHPVSTHCKGQHGVHDDVFLSLPCVLGSEGITDIINQTLKKEEEAQVQKSAETLWNVQKELTF
What are the official names of this protein?
L-lactate dehydrogenase, LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_XANAC
Sequence: MTTINQLVRKPRQATTYKSASPALDKCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNQEEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDAAGVAKRRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NUOK_RHOP5
Sequence: MTGAELTGFMILAAGLFAAGVFGVLARRGILFQLIALEVALSGPALAFIAAGAYHGDAEGQGMFVLTLTLAAAEVAVGLALFLRIRRAKGSDDSDAVSGLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL17_FRAT1
Sequence: MRHRKQGRKFGRTSSHRKAMFKNMSASLINHELIKTTLPKAKELRAIVEPLVTLAKREHKLRQELDTNSNEFKAQSVALRRQAFDFLRNKAAVTKLFEEFGARYAERAGGYTRILKCGYRFGDKAPMAFIELVDRPQVEEAADEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: VDAC1_WHEAT
Sequence: MGGPGLYSGIGKKAKDLLYRDYQTDHKFTLTTYTANGPAITATSTKKADLTVGEIQSQIKNKNITVDVKANSASNVITTITADDLAAPGLKTILSFAVPDQKSGKVELQYLHDYAGINASIGLTANPVVNLSGAFGTSALAVGADVSLDTATKNFAKYNAALSYTNQDLIASLNLNNKGDSLTASYYHIVEKSGTAVGAELTHSFSSNENSLTFGTQHTLDPLTLVKARINNSGKASALIQHEFMPKSLCTISAEVDTKAIEKSSKVGIAIALKP
What is the function of this protein?
Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).
What are the official names of this protein?
Mitochondrial outer membrane porin, Voltage-dependent anion-selective channel protein, VDAC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL6_DECAR
Sequence: MSRIGKNPVVLPAGVEVTVGEQIVVKGPLGSLKTAAHSAVNVAVEGQNVTVSKVAGAANAAAMWGTMRANLNNMVTGVSKGFERKLQLVGVGYRAQAQGDTLNLSLGFSHPVAHKMPAGVKVECPTQTEILIKGSDKQQVGQVAAEIRAYRKPEPYKGKGVRYADEVVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MURD_BACC4
Sequence: MKTVTEFQNKNILVLGIAKSGYAAATLLQKLGANVIVNDGKPLAENVLAAELQAKGMDVVCGGHPLELLERNISLVVKNPGIPYSNPILVAAKEKQIPIVTEVELAYRISEAPFVGITGSNGKTTTTMLTFEMLKEGQKHPVIAGNIGTVACEVAQDAKENEVVVTELSSFQLMGVELFQPKIAAFLNLFEAHLDYHGTKKEYGLAKANIFKNQTENDYSVINADDADVMALSAYSKGQKILFSTTKEIEDGACIKDNALYFKGEKVVEVSDIVLPGQHNLENILAAMSIAKLLGTSNEAITVVLKRFTGVKHRLEYVTTINNRKFYNDSKATNMLATEKALSAFTQPIVLLAGGLDRGNEFDDLIPYFKNVKAIVTFGQTAPKLVRAAEKAGLDIIESVDTLDEAVVKAYAHSKDGDVVLLSPACASWDQFKTFEERGDIFIQAVHKLI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE3_ARATH
Sequence: MNDADASIQIQQMVRFIRQEAEEKANEISISSEEEFNIEKLQLVEAEKKKIRQEYEKKEKQVDVRKKIDYSMQLNASRIKVLQAQDDIVNAMKEEAAKQLLKVSQHGFFNHHHHQYKHLLKDLIVQCLLRLKEPAVLLRCREEDLDIVESMLDDASEEYCKKAKVHAPEIIVDKDIFLPPAPSDDDPHALSCAGGVVLASRDGKIVCENTLDARLEVAFRNKLPEIRKSLFGKVGAA
What is the function of this protein?
Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit E3, V-ATPase subunit E3, Vacuolar H(+)-ATPase subunit E isoform 3, Vacuolar proton pump subunit E3.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: STHA_YERPA
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTIKSSFADILNHADRVINQQTRMRQGFYDRNHCHMFSGDASFIDANTVNVRYADGTSDTLQADNIVIATGSRPYRPVNVDFNHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTTDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLENIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANVHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_GLUDA
Sequence: MSKPKHPRTLAETEAQALTRNIRVSPRKLNLVAGLIRNKPASQAVAILTFSKRRIAQDVRKTLESAIANAENNHQLDVDQLVVVRAEVGKSIVMRRFHARGRGRSSRIEKFFSHLKIVVAERAAEAETTEQKAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MA658_ARATH
Sequence: MGSLQTPIEMRSSSLLDTSCGYLLRELQMIWDEVGEDKFEREKVLLDIEQECVEAYRRKVDHANVSRSRLHQELAESEAELTHFLLCLGERSVPGRPEKKGGTLREQLDSIAPALREMRLRKDERVKQFRSVKGEIQKISAEIAGRSTYEDSTRKITIDDNDLSNKKLEEYQNELHRLHDEKNERLQKVDIYICAIRDLSATLGTEASMIITKIHPSLNDLYGISKNISDDILKKLNGTVVSLEEEKHKRLEKLHHLGRALSNLWNLMDASYEDRQKFFHVIDLLSSAPSDVCAPGSITLDIIQQAEAEVKRLDQLKASRIKELFIKKQKELEDTCNMSHMETPSTEMGNITNLVDSGEVDHVDLLAAMDEKIARAKEEAASRKGIIEKVDRWMLASDEERWLEEYDQDENRYSVSRNAHRNLRRAERARITVSKISGLVESILVKAKSWEVERQKVFLYNEVPLVAMLQEYNKLRQEKEMEKQRLREMKKMSIPQPVAEGDNFYMARPASSNRRISNRSMNGGFGSGSPINRKYSGGFNNTNNNYTALGTSIRRESRKSEA
What are the official names of this protein?
65-kDa microtubule-associated protein 8, AtMAP65-8.
What is the protein family that this protein belongs to?
Belongs to the MAP65/ASE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=Present in MT cortical arrays. Concentrated in dots surrounding the nuclei.
Protein: ENO_THET8
Sequence: MTTIVGVRAREVLDSRGFPTVEAEVELEGGARGRAMVPSGASTGTHEALELRDGGKRYLGKGVRRAVENVNERIAPELVGMDALDQEGVDRAMLELDGTPNKANLGANAVLAVSLAVARAAAEALGLPLYRYLGGVQGVTLPVPLMNVINGGKHADNRVDFQEFMLVPAGAGSFAEALRIGAEVFHTLKAVLKEKGYSTNVGDEGGFAPDLRSNEEAVELLLLAIERAGYTPGQEVSLALDPATSELYRDGKYHLEGEGKVLSSEEMVAFWEAWVEKYPIRSIEDGLAEDDWEGWRLLTERLGGKVQLVGDDLFVTNPERLRAGIERGVANAILVKVNQIGTLSETLEAIRLAQRSGYRAVISHRSGETEDSFIADLAVAVNAGQIKTGSLSRSDRLAKYNQLLRIEEELGRAARFLGYAAF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRPD_NEIG1
Sequence: MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILTGLRIKVETVSEITAAAAVMCEFASKVPLEDADGLVDIVGTGGDGAKTFNISTTSMFVAAAAGAKVAKHGGRSVSSSSGAADVMEQMGANLNLTPEQIAQSIRQTGIGFMFAPNHHSAMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHVLVVCGEGGLDEITLTGKTRVAELKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESLLKMNEVLDGKEGAARDIVLLNTAAALYAGNIAASLSDGISAAREGIDSGRAKAKKEEFVGFTRQFA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NORA_STAAR
Sequence: MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIADVSPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFYFAGALGILAFIMSVVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPAILTLVLAFGLSAFETLYSLYTSYKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLIYSVIVLVLLVIADGYWTIMVISFAVFIGFDMIRPAITNYFSNIAGDRQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKQQDL
What is the function of this protein?
Involved in quinolone resistance.  May constitute a membrane-associated active efflux pump of hydrophilic quinolones (By similarity).
What are the official names of this protein?
Quinolone resistance protein NorA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_BACSU
Sequence: MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYPVEESKERDVTYSAPLRVKVRLINKETGEVKDQDVFMGDFPIMTDTGTFIINGAERVIVSQLVRSPSVYFSGKVDKNGKKGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEILDLIGENEYLRNTLDKDNTENSDKALLEIYERLRPGEPPTVENAKSLLDSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAEKGQILDRRTLDKVLPYLENGIGFRKLYPNGGVVEDEVTLQSIKIFAPTDQEGEQVINVIGNAYIEEEIKNITPADIISSISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNTITPQQLINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNRFGFIETPYRRVDPETGKVTGRIDYLTADEEDNYVVAQANARLDDEGAFIDDSIVARFRGENTVVSRNRVDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMQPEAPFVGTGMEYVSGKDSGAAVICKHPGIVERVEAKNVWVRRYEEVDGQKVKGNLDKYSLLKFVRSNQGTCYNQRPIVSVGDEVVKGEILADGPSMELGELALGRNVMVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDDRGIIRIGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIIHDVKVFNREDGDELPPGVNQLVRVYIVQKRKISEGDKMAGRHGNKGVISKILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHMGMAARYLGIHIASPVFDGAREEDVWETLEEAGMSRDAKTVLYDGRTGEPFDNRVSVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGDNVPEPGVPESFKVLIKELQSLGMDVKILSGDEEEIEMRDLEDEEDAKQADGLALSGDEEPEETASADVERDVVTKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DER_BRADU
Sequence: MSFTIAIIGRPNVGKSTLFNRLVGQKLALVDDLPGVTRDRREGEARLGDLEFTIIDTAGLDEGAKGSLTARMQEQTEAAIAQADALFFVVDARIGLTPTDRAFADFARRANKPVLLVANKSEGKHGDAGAMEAFALGLGDPIQISAEHGEGMGELYDALAKLMPEPVEEDEDEDDAPLSEEEAATRPIRVAIVGRPNAGKSTLINHLLGEERLLTSPEAGTTRDSIAVEINWKGREFRVFDTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDTQNRFEEQDLRIADLVEREGRALVLAANKWDLMETKGGGAISGLRRDADHWLPQVKGVPIVAVSGLMGEGIDRLMQAIQDAYAVWNRRVSTSALNRWFEQAVQANPPPAVSGRRLKLNYITQTKARPPSFVLFCSRADAVPQSYLRYLTNSMREAFDLPGTPVRITLREKANPFAHKRKRPS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SPRC_PIG
Sequence: MRAWIFFLLCLAGKALAAPQQEALPDETEVVEETVAEVPVGANPVQVEVGEFDDGAEEAEEEVVAENPCQNHHCKHGKVCELDENNSPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDENNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFQTCDLDNDKYIALDEWAGCFGIKEQDIDKDLVI
What is the function of this protein?
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines.  Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes.  There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity).
What are the official names of this protein?
SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine.
What is the protein family that this protein belongs to?
Belongs to the SPARC family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Protein: PFMAF_PESFW
Sequence: MSPPHSEHSNVPSDVAAGGGPKKSPPAGTQKLRAPRMRASCDGCFLAKVKCSKGKPMCQRCMTTGLACKYSPSSRSGKPKASDNGNILNGAPRHAKREGLQFSSPVFEGSQDLMAGPAQFMQNNWGSNQQAMWDLPTHQDPGTNFGSGPLNESLGQDIGIMDGISHDGGVMPFSENLADTNPWQSQNPSSSFSQMLPGSSGSMIHGRSQSTDMMISLVAANFQDTNAQAGPSHGPPLGQMAGPSHGPLGQMAVPLHGPPLGQMAGLSHGPLGQMTSPPNPAHARHHSDPAIGTGHVLSCNFDCTHQSLQRLNFMLATSSWPSDMLMTANENLCDAWRVIMRCPNCMGSGARRYMALAFLATSMQIQSRRLQAFLDTVKPNHDGVFPTVSNPAEKLNRLGTAITQIDQAYALLLRSFNNEMIEHPGVAQALANGVHKSLDAAVSLLLRKRTELAGTN
What is the function of this protein?
Transcription factor that positively regulates the expression of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations (PubMed:28517364).  PfmaF assists PfmaH in promoting melanin synthesis.  PfmaF may function as a broad regulator promoting also other secondary metabolism as well as fungal development (PubMed:31116900).
What are the official names of this protein?
Transcription factor PfmaF, Conidial pigment biosynthesis cluster protein F.
What are the subcellular locations of this protein?
Nucleus.
Protein: UNG_PORG3
Sequence: MKEVQIEAGWKKVLQEEFDKFYFEKLTDFVREEYRQSPIYPPARFIFRAFDTCPFDRVKVVILGQDPYHEPGQAEGLAFSVPTGIPIPPSLRNICEEIRTDTGQPAHIDGGSLLPWVEQGVLLLNATLTVRASQAGSHQGHGWETFTDAAIEALAKRREHLVFLLWGSYARRKSAMIDPRRHLILEAPHPSPLSAHRGFFGCKHFSRTNAYLRQHGIAPIVW
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_ALIFM
Sequence: MDKKASRIRRATRARRKIAELCATRLVVHRTPRHTYAQVIAPNGSEVIAAASTVEKAIREQLGNTSNKAAAEAIGKLIAERAIEKGITNVAFDRSGFQYHGRVAALAESAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL21_UREPA
Sequence: MFAIFQTGGKQYKVQQGEKIYVEKLDLEVGSKISFDQVIMVEGSVGTPFVKNAVVNATVIKQGKQKKINIIKFKSKKHHLKRQGHRQPYTQLVIDSISVK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RFA1B_ORYSJ
Sequence: MDSDAAPSVTPGAVAFVLENASPDAATGVPVPEIVLQVVDLKPIGTRFTFLASDGKDKIKTMLLTQLAPEVRSGNIQNLGVIRVLDYTCNTIGEKQEKVLIITKLEVVFKALDSEIKCEAEKQEEKPAILLSPKEESVVLSKPTNAPPLPPVVLKPKQEVKSASQIVNEQRGNAAPAARLAMTRRVHPLISLNPYQGNWIIKVRVTSKGNLRTYKNARGEGCVFNVELTDVDGTQIQATMFNEAAKKFYPMFELGKVYYISKGSLRVANKQFKTVHNDYEMTLNENAVVEEAEGETFIPQIQYNFVKIDQLGPYVGGRELVDVIGVVQSVSPTLSVRRKIDNETIPKRDIVVADDSSKTVTISLWNDLATTTGQELLDMVDSAPIIAIKSLKVSDFQGLSLSTVGRSTIVVNPDLPEAEQLRAWYDSEGKGTSMASIGSDMGASRVGGARSMYSDRVFLSHITSDPNLGQDKPVFFSLNAYISLIKPDQTMWYRACKTCNKKVTEAIGSGYWCEGCQKNDAECSLRYIMVIKVSDPTGEAWLSLFNDQAERIVGCSADELDRIRKEEGDDSYLLKLKEATWVPHLFRVSVTQNEYMNEKRQRITVRSEAPVDHAAEAKYMLEEIAKLTGC
What is the function of this protein?
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication.  The activity of RPA is mediated by single-stranded DNA binding and protein interactions.  Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity).
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit B, OsRPA70b, Replication factor A protein 1B, Replication protein A 1B.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SERC_SHEB8
Sequence: MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTQQAESDLRELMQIPTNYHVLFMHGGGRGQFSAVVNNFLGNHGRALYLVSGQWSSAALAEAQKLVGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFNTPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDGEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.