PharMolix/UniProtQA huggingface dataset:
Protein: FEMA_STAA8
Sequence: MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVGIKNNNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRCLYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSVLDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRFLSEEELPIFRSFMEDTSESKAFADRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPENKKAHNKRDNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSNAFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIEYVGDFIKPINKPVYAAYTALKKVKDRIF
What is the function of this protein?
Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  Adds glycines 2 and 3 of the pentaglycine bridge, using glycyl-tRNA(Gly) as donor.  Involved in resistance to methicillin.
What are the official names of this protein?
Aminoacyltransferase FemA, Factor essential for expression of methicillin resistance A, N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA21B_RABIT
Sequence: MKFLVLAALLTAGTAASGVSPTALWQFRGMIQCTIPGSSPYLEFNGYGCYCGLGGSGTPVDELDRCCQTHDQCYTQAKKLSSCSFLVDNPYTNSYSYSCSGTTVTCSSKNKECEAFICDCDRKAAICFSKRPYNKEYKPISKYC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines.  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity).  May act in an autocrine and paracrine manner (By similarity).  Has anti-helminth activity in a process regulated by gut microbiota.  Upon helminth infection of intestinal epithelia, directly affects phosphatidylethanolamine contents in the membrane of helminth larvae, likely controlling an array of phospholipid-mediated cellular processes such as membrane fusion and cell division while providing for better immune recognition, ultimately reducing larvae integrity and infectivity (By similarity).
What are the official names of this protein?
Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted from pancreatic acinar cells in its inactive form.
Protein: AROA_MYCUA
Sequence: MSSIEPWPAPFAPTPVHATVTVPGSKSQTNRTLVLAALAAAQGQGSSTITGALRSRDTDLMIEALQTLGLRVDGTGSELTVSGRIRPCPEARVDCGLAGTVLRFAPPLAALSAAPITFDGDEQARARPIAPLLDALRGLGVPVDGAGLPFRVQGTGSVAGGTVAIDASASSQFVSGLLLSGASFTDGLTVQHTGSELPSAPHIAMTVQMLRQAGVDVDDSIPNRWLVRPGALRPRHWDAEPDLTNAVAFLAAAVVTGGTVTITGWPADSVQPAKNILDILQTLNSTVRHIDSCLQVQGPQSYRGFDVDLRDVGELTPSVAALAALASPGSVSRLAGIAHLRGHETDRLAALSTEINRLGGNCEQTSDGLVITATPLRPGSWRAYADHRMAMAGAIVGLRVAGVEVDDIGATSKTLPEFPQLWTEMVEGSSG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C1_XENLA
Sequence: MTSYRSSSASYYSGSSSKGGFGSRSLAGSNSYGGSSFGAGFSSGVGSGFSSSGGNFAMAEAASSSFGGNEKHAMQNLNDRLASYLEKVRALEATNSDLEGKIRNWYDKQSDAGIGAGSKDYSKYFEIIAELRNKIRAATIDNATVTLQIDNARLAADDFRLKFENELALRQSVEGDSNGLRRVLDELILARGDFELQIESLTEELAYLKKNHEEEMSHAKSQSAGKVSVEMDAALGVDLTSILNNMRADYEILAEKNRRDAELWFNQKSGELKKEISVGVEQVQASKSEITELKRSLQSLEIELQSQLAMKQSVEGNLNELQGFYSSQLQQIQNTIGSLEEQLLQIRSDMEHQNTEYKLLLDIKTRLEMEIQTYRRLLEGELGQVTTVANTSSVESKTESSSTSTTRTRMVKTIVEEVVDGKVVSSRVE
What are the official names of this protein?
Keratin, type I cytoskeletal 47 kDa.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RD18_PHYIT
Sequence: MSHQRILLLLMAAFFAWVSAQTPPGQADKSKLIAHDVLMKTTSLSETTIATSSKRFLRLYDAEVRDTVRGDNDVDREERGTTPLLSKVDDLIHKVFKSNPEQAQIKAWMKSRVHPQAIFDTLRLAKSTTKLNDDPNLLLWLKLVAAFRAKNGNQAFSDLDLYYLLLKRSSGEELKILIESFRKTGALKELGKSMQKSLSGSWVSKTLQHETDPKIVYDTLRLQEAGTKLVDSPIFHQWLAYAQQYRAQKGNHWFGDDDMLDLFRKTMPEKDVVTLLHLLRNVPGMKDHGDTMQRFLFLSSKTSRKMMHDVWLNYDVTPEQVFKILRLVKVNMDAVDTNAMFIHWLRYVNLYRSHTKKNVLSSVQMVHFLADTKPLRSEWQFATFFESLKDVPDLKRLAENMQTYLFQNWLHTEWDPKAVSSMLAIPFPTSAVYLPKNDPIYKTWVAYTLYYTERKGGVSLLNKVKTLLDNDNPIGALTAAMKAQ
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PexRD18.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: MED25_DROME
Sequence: MEVDQIPLADVVFVIEGSAINGAYINELKTNYILPTLEHFTTGSIDEREYLIAERFATLYGIVVYRTAANLLEPVCSTYGPFLQPQKVMETIERLPLVGGGMESCAHMAEGFAAAHGCFDDISERRQLLDQTSVQRHCILICNSPPYQMPTTESWKYPGKSCEQLAALFNERKINLSIIAPRKMPVLFKLFMKADGDQPITSKNYAKNIRHLVLLKGYSLKERAPSPNSMAAQMAAPNAAQATVQQQQQQQQNQAGQQQQGQGMPMDTTPAQQQQQQQQQQQQQQQQGNPQQQVMNMNTMQQQQPGPNPPAGLLNPQQQQQLLQQQQQNQFVSNQMQNQNFQQNVGPGQNRWMYPNQPGQARPPFMQGAGNVGGVGQGGGMQQNPNSALISRINAPPPNQTVTSLQQQQQQQAQQQQQQQQQAQQQQQQRMQMLSQQQMLNHQQLQQQQQLAQQQQQQQQGQQQQQVNPNAGNNMMPASNAGNMSNPQQQQQQVGQQSNPQQQGNPQQQQQGNSQQEQASLREKIWTGVLEWSEKPKSDQQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTSGYAGCVHFSSIPNSPACDLKVLILLYTPDRNAFLGFIPNNQAMFVERLRKVIQQKQHGNMQQQQQQQQMMQQQGKSPMELQQQQQQQQQQQQMQQDNSQQQHYNQFQLNMQMGGGGPGGGPGPGPGGMPMQQNQMQMNMMQQQRMPLGVGVGVGVGPGGVPNPNLQQQLQQVAPNVAAMQQQQAQQQQQRMVRPMMSNNNPGLRQLLQHQTTPGNQFRPQMGGQNPNQMGAGGPMVGNRNFDDGNYEFM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).  Required for activated transcription of the MtnA, MtnB and MtnD genes.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 25, Mediator complex subunit 25, dmPTOV2.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEXA_VIBA3
Sequence: MKPLTPRQQQVFDLIKSKIEDCGMPPTRAEIARELGFRSANAAEEHLKALARKEAIEIIPGASRGIRILLEDAANEEQGLPLIGQVAAGEPILAQEHVEMHYQVDPGMFKPQADFLLRVNGESMKDIGIMDGDLLAVHKTQDVRDGQVVVARVDDDVTVKRLERKGSTVLLHAENEEFSPIHVDLESQHLSIEGLAVGIIRNTDWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: YL764_MIMIV
Sequence: MYFHITYSDLDINETHDDDLKDFLIIPEEDIFGQFVTHILDPNENDLYEIEPDKICKNPFSSSIYTNNITIKNKYSLLDANIYEILLSKGISKYIDGLLVWAINFNLLWLLELIYNYKPPINLKDREIYLNSNCDDINLIKFIVTRNDYFQINLESLLEYVDNKEIIIYLMDFIDTDKIVKYVIGNCSSEFFIDCIKGNTILTQEHIKLAVQNRKIPVLEHLINLGIEYDLNEIINDIKDFDILKYMLEIGNSLNEDNVNIIIFNIHTTQLIEYLMNLGYTINSKLVISMFSHMLIVSENTDIVEFLKSINAKDSDLTVDFIEYLLEDNFEKAKQIMEYFPGANTVIDCNLFLKYAIISQDIPNIEYSINKGADLKKYYKNILLTNNVTILDLCLNHCEINDVNNFILKIIENDCIETLKYLVDNNYNIDLLDMFQIMVKKNYYNPIRKYICEQIKNNNLLIPNLVEIIMNLFFDDGDVNWILKYNFEYQYKDNLDEIIMTIIIGDCDGAKNMIMNYNYTSDLKVLYAFILKEFPEECSSEKMDTIKFLLDFNADNNEYVQSAFLLSVFYTPLLKYFVEDKQIDLTVNGQNIVEYLISDGDHEIFRYLYYNGFDVKNNGFEIINAHNSNNECAITKLIESIKNNTYQ
What are the official names of this protein?
Putative ankyrin repeat protein L764.
Protein: DRC7_MOUSE
Sequence: MEVLREKVEEEEEAEREEAAERAERTEKLERVTKSAEVSREGTILSQDELRDLEGKLMAIEIPTQADHSVISQAPVDVTKLPPSYTTNSLKEEHLLLVADNFSRQYSHLCPDRVPLFLHPLNECNVPKFVSTTLRPTLMPYPELYNWDSCAQFVSDFLTMVPLVDPLKPPTHLYSSTTVLKCQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCLMDLTREVCPLTVKAKEIVKKKEKTVPKKYSIKPPRDLTSKFEQEQEEKRIQEIKDLEQRRLKEEEDRILEAEKAKPDPLHGLRVHSWVLVLAGKREVPESFFIDPLTARSYSTKDEHFLGIESLWNHKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKPHLSLTEEDEEGLDDDDDDVEDLGKEEEDKSFDMPSSWVSQIEITPEEFETRCPSGKKVIQYKKAQLEKWSPYLNNNGLVCRLTTYEDQQCTKVLEIKEWYQNREDMLELKHINKTTGLHVDYFKPGHPQALCVHSYKSMLPEMDRVMEFYKKIRVDGLVKREETPMTMTEYYEGRSDFLAYRHVNFGPRVKKLSQSSVESNPRPMVKITERFSRNPEKPADEDVAERLFLIVEERIQLRYHCRDDYITASKREFLRRMEVDSKGNKIIMTPEMCISYEVEPMEHTKKLLYQYETMNQLKNEEKLSRHQAWESELEVLEILKLREEEEEAHTLTISIYDTKRNEKSKEYREAMERVLHEEHLRQVEAQLDYLAPFLAQLPPGEKLTRWQAVRLKDECLSDFKQRLIDKANLIQARFEKETQELQKKQQWYQENQVTLTPEDENLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRLIDFVKVFV
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity).  Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (PubMed:31961863).  Not required for ciliogenesis in the brain and trachea (PubMed:31961863).
What are the official names of this protein?
Dynein regulatory complex subunit 7, Coiled-coil domain-containing protein 135, Coiled-coil domain-containing protein lobo homolog, Spermatogenesis-related gene in late stages of spermatogenesis cells protein.
What is the protein family that this protein belongs to?
Belongs to the DRC7 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Associated with the outer doublet microtubules (OD).
Protein: ISTB_BACTB
Sequence: MKNSYQQLTTNLEYLKLKQMAQHLGDVVDFSINNELSFVETLVKLTNYEIDVREQNMIHSMVKMGAFPHRKEVDEFDFEFQPSINKQQILDFISLRFLEQQENIVFLGPSGVGKTHLATSIGIAAAKKRTSTYFIKCHDLLQNLKRAKIENRLESRLKHYTKYKLLIIDEIGYLPIDPEDAKLFFQLIDMRYEKRSTILTTNINFKSWDEVFQDPKLANAILDRVLHHATVVSIVGQSYRIKDHFSKEND
What are the official names of this protein?
Insertion sequence IS232 putative ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the IS21/IS1162 putative ATP-binding protein family.
Protein: RL333_STAAC
Sequence: MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHKESK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: FAD12_PUNGR
Sequence: MGAGGRMTVPNKWEGEGDEKSQKPVQRVPSAKPPFTLSEIKKAIPPHCFKRSLLKSFSYVLYDLTLVAIFYYVATTYIDALPGPLRYAAWPVYWALQGCVLTGVWVIAHECGHHAFSDYQWVDDCVGLVLHSALLVPYFSWKYSHRRHHSNTGSLERDEVFVPKPKSKMPWFSKYLNNPPGRVMTLIVTLTLGWPLYLALNVSGWPYDRFACHFDPYGPIYTDRERLQIYISDVGIMAATYTLYKIAAARGLAWLVCVYGVPLLIVNAFLVTITYLQHTHPALPHYDSSEWDWLRGALATADRDYGILNKVFHNITDTHVAHHLFSTMPHYHAMEATKAIKPILGDYYQFDGTPVYKAMWREARECLYVEPDDGANSKGVFWYKKNL
What is the function of this protein?
Delta(12)-fatty acid desaturase producing in a heterologous system linoleic acid (18:2(9Z,12Z)) and to a lower extent hexadecadienoic acid (16:2(9Z,12Z)).
What are the official names of this protein?
Delta(12)-acyl-lipid-desaturase, Delta(12)-oleate desaturase, PgFAD2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: APBC_SALTY
Sequence: MNEQSQAKSPDTLRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWNSAFEVLKEQCSADLLRITGAKAIDWKLSYNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGVLDADIYGPSIPTMLGAEDQRPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGTGGAQKLAEKYHTQLLGQMPLHISLREDLDRGTPTVVSRPESEFTAIYRELADRVAAQLYWQGEVIPGEIAFRAV
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins (PubMed:18616280, PubMed:19001370).  Can hydrolyze ATP (PubMed:12486045, PubMed:19001370).  Both activities are required for function in vivo, but the ability to hydrolyze ATP is not necessary for Fe-S cluster transfer (PubMed:19001370).
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: RIMO_XANP2
Sequence: MADTVLNSAPSKAAPRISFVSLGCPKALVDSERIVTRLRAEGYELTKTHQGADLVVVNTCGFLDSAKAESLNAIGEALAENGKVVVTGCMGAEPEQIREVHPSVLAITGPQQYESVLAAVHEAVPPAHDPFLDLVPAEGVKLTPRHYAYLKISEGCSNRCTFCIIPKLRGDLVSRPAGDVLREAERLVKAGVKELLVISQDTSAYGVDLRYATSPWGDKEVAARFLDLAGALGDLGAWVRLHYVYPYPHVDAVMELMAAGKVLPYLDIPFQHASPTVLKRMKRPASQEKTLARIQAWRAAVPDLTLRSTFIVGFPGETEAEFEELLGFLEEAEIDRAGCFKFEPVRGADANALENPVPDAVKAERYDRFMRTQQKVSARRLKRKVGTRQSVIIDTVTPDGGIGRTKGDAPEIDGTVKVFARRPLRVGEIATVKIEAAGPYDLSGTAVGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_WIGBR
Sequence: MAKSDYYDILGISKNASDREIKTAYKRLAVKFHPDRNPGNLEAESKFKEIKEAYEVLLDPKKRAAYNQYGHTAFDQGSSNTEFTSNADFSDIFGDVFGDIFGNNRRKRSNRGSDLQYNINLSLEEAVKGISKEITIPKLERCNICSGKGMQPGTSAQNCSTCNGQGQIQMRQGFFSVQQTCPSCRGKCKIIRFPCRNCSGQGRVERSKNISIRIPAGVDNGDKIRLSGEGEAGKLGGSSGDLYVKISVKEHPIFKREEHNLYCEVPINFAMAALGGDIEVPALDGRVKLRIPAETQTGRLFRMRGKGVKSIRSGHQGDLLCRVVVETPVRLSEKQKSLLKELGISFVGRTGMYNSPRSKSFFDGVKKFFDGLTN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_LEGPA
Sequence: MKQKFKRAILYARQHRANQEVNESLHRLVDFLSTQDIEIFQDSDTAASFELKAPVLPREKMGAKHDLIIVVGGDGSLLSASRMAIKVNTPVIGINRGRLGFLTDILPQDIESHLGPVLNGQYNEEERFLLHTKIYDKENSYFEGDALNDVVLGRGSETHLIEFDVYINQQLVSHYRSDGMILSTPTGSTAYALSAGGPIMHPQLNAIVLVPMFSHSLSSRPLVIDGEAEIELYISKSNETDLRISCDGHESRVVKPGQKVAVKKNGNRLRLLHPLDYHYYDTLRSKLGWESKHQG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BURVG
Sequence: MSAPLTLALSKGRIFEETLPLLAAAGVQVAEDPETSRKLILPTTDPNLRVIIVRASDVPTYVEYGAADFGVAGKDVLVEHGGSGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMSISSRLVVNQAALKLKRTALKPFLDAFERASQNGN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SHEAM
Sequence: MSITKDQILEAFAAMSVMEVVELIEAMEEKFGVSAAAAVVAGGAADAGAAAEEKTEFDVVLTSHGDNKVGVIKAIRGATGLGLKEAKAMAEAAPVAVKEAVSKEEAEALKKELEEAGAQVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y165_RICAH
Sequence: MGDKIFHNLSSKTLVATPHVITKGIYHKSLIYMLSHTEEGAIGLIFNRLVNHIDLKSFFKIKNDDITTPVMVPIYLGGPVEHEKGFFLHSSDYNKNLLLDFQNDLAVSSNLEISEDIAFGKGPKNSLFIVGYTAWKPGQLEEELERNLWLVMDCNKEFIFADNPEDKWHSALKHLGIDEIYFSAQIGNA
What are the official names of this protein?
UPF0301 protein A1C_00165.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GALP_ECOLI
Sequence: MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIADEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAAPNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLSDTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTSAEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPKIFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVLGTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTATNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERNLMKGRKLREIGAHD
What is the function of this protein?
Uptake of galactose across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
Galactose-proton symporter, Galactose transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RCBT2_HUMAN
Sequence: MEEELPLFSGDSGKPVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFRSSLEDNEDDIVEMSEFSYPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLKKLCQQTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLLKNFISKASRVGAFKN
What are the official names of this protein?
RCC1 and BTB domain-containing protein 2, Chromosome condensation 1-like, CHC1-L, RCC1-like G exchanging factor, Regulator of chromosome condensation and BTB domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly found in the acrosomal cap region.
Protein: CCDB2_ECOLX
Sequence: MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTQMVSVPVSVIGEEVADLSHRENDIKNAINLMFWGI
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system, functioning in plasmid maintainence.  Responsible for the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system.  Half-life of over 2 hours.  Interferes with the activity of DNA gyrase, inducing it to form a covalent GyrA-DNA complex that cannot be resolved, thus promoting breakage of plasmid and chromosomal DNA.  Toxicity is inhibited by labile antitoxin CcdA, which blocks the activity of CcdB; CcdA also removes bound CcdB protein from the CcdB-GyrA complex by forming a CcdA-CcdB complex, a process termed rejuvenation.  Functions as a transcriptional corepressor for the ccdAB operon, repression also requires CcdA (By similarity).
What are the official names of this protein?
Toxin CcdB, Cytotoxic protein CcdB, Protein LetD.
What is the protein family that this protein belongs to?
Belongs to the CcdB toxin family.
Protein: MNME_STAS1
Sequence: MDLDTITSISTPMGEGAIGIVRLSGVDAVDIADKLYKGKERLEDVTSHTINYGHIIDPESNEVVEEVMVSVLRAPKTFTREDIVEINCHGGILTINRILELTMTYGARMADPGEYTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDMIKRQRQSILEILAQVEVNIDYPEYDDVEDATTEVLLGKSNEIKTEINKLLDTGTQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVPGTTRDTLEEYVNVRGVPLRLVDTAGIRDTEDIVERIGVERSRKALGEADLILFVLNYNERLTDEDRKLYEVIKNEDAIVIVNKMDLDKHLDLDEVKDMIGDMPLIQTSMLKQEGIDQLEIQIRDLFFGGDVQNQDMTYVSNSRHISLLKQARNTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGESASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_HUPLU
Sequence: MPIGVPKVPFRLPGDEDAVWIDVYNRLFRERLLFLGQQVDDELANQLICIMIYPNGEDDSRDMYLYVNSPGGAVFAGISIYDAMQFVVPDVQTICIGLAASMGSFVLAGGEITKRIALPHARVMIHQPASSYYEGQVGECIMEAEEVLKIRDCITKVYAQRTGKPLWVVSEDTERDVFTSAEEAKVYGVIDPVAVETSSNSPISKLTKS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ASSY_METBA
Sequence: MAKKVALAYSGGLDTSVCIPILKEKYGYDEVVTISVDVGQPEEEIKRADAKAEKISNKHYTIDAKEEFVKDYVFPLIKANGSYEGYVMGTSIARPLIAKKVVEAARKEGAVALAHGCTGKGNDQLRFEAVFRQTDMDVIAPMREMNLTREWEIDYAKEHGIPVEVTKSKPWSVDENIWSRSIEGGRLEDPSFVPPEEIFEWTTSPEKAPEQPRVVDIGFEAGVPVSLDGEKMSGYAFVKKMNEIAGENGVGRTDMIEDRVLGLKARENYEHPAATVLRQPNSRPLRNSSLTRSELKFKKIVDDQWSELAYYGLVDEPLYADLNAFIDKSQERVTGIVKVRLYKGALTILARSSPNALYSEDLVSFDSQTIDQKGSEGFAKYHGFQARMYRKVMDKQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.