PharMolix/UniProtQA huggingface dataset:
Protein: PRP46_CANAL
Sequence: MSVTATSHDILKSIDDSILPPEDTLSEAMYNNVKLDHYFNKLPKSSEENNINDQTNQLIVSAAPESEDSPAAEWKLLRTLAGAHQGWIRAIALDEITNKWYVTGSADSTIKIWDFENNSLKAVLTGHVLGIRSLCISKRHPYLFSGGEDKSLRCWDLERSNSDAGCQIRSYHGHLGGVYSIGLHPELDVLFSGGKDCVVRVWDIRSRVEAMTLLGHTNDITSIETDYNDPQVITSSMDGTIRLWDLRKSKTELLITNHSKSIRSMKSHPKEATFVSGDSNGEIKQWLLPKGELLNEFGTSQLSPNQRDNSRIINTLAINPVTNTLFSGYDDGKLEFYNYTTGNLQQSGQSPSLAGPEQSAIYASTFDMSGLRLLTCHGDKSIRIWGTSY
What is the function of this protein?
Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
What are the official names of this protein?
Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 46.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_LACH4
Sequence: MLKYFGTDGVRGVANQGLTPEMAFKLGRDGGYVLTKNKKDGEQAKVLVSRDTRISGQMLEYALISGLLSVGIEVLEVGVITTPGLSYLVRAQGADAGVQISASHNPVEDNGIKFFGSDGLKLSDEMEEEIEKLIDAKGDNLPRPSAEGLGTVTDFHEGSAKYLQFIENTIPEDLDGIKVVIDGANGASSALISRLFADCGVDFTTIYTHPNGLNINDHCGATHTENLQKEVVKQGAQLGLAFDGDADRCIAVDENGNEVDGDHIMYVIGSYLAEHGRLKKDTIVTTVMSNLGFTKALEKEGLKNVRTQVGDRYVSEEMRAHGYNLGGEQSGHVIMSDYHNTGDGMLTGLHLMLVMKKTGKSLSELLKDFKDYPQGLVNVPVKDKKSWKEHQPILDVIAEVEKDMNGNGRVLVRPSGTQDLLRVMAEGPTQEETDAYVDRIVKVVEKEMGK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TSGA_BUCAI
Sequence: MTNINRIGLTWISFLSYAFTGALVVVTGMIMGNISNYFHLSISQMSNIFTFLNAGILVSIFINSWLIEIISLKKQLIFSFILTIIAVIGIVLCNSIFLFSINMFILGLVSGITMSIGTFIITHLYSGSKRGSLLLLTDSFFSMSGMIFPIVTAYLLEKKIIWYWSYICIGAIYLLIFLLTINSSFEKFKTNTKNSKETKEKWNFNVFLLSISALLYILGQLGFISWVPQYATEIMNIDIKKTGSLVSGFWMSYMLGMWFFSFIIKFFNLYRMFIFLTSMSTILMYCFIKSENFLNQQYIIISLGFFSSAIYTIIITLASLQTKHPSPKLINLILLFGTIGTFLTFIITSPIVEAKGLYVTLISSNILYGIVFFLSILIYFNKKYERVI
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TCAA_STAAW
Sequence: MKSCSKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKTVIAEANKVTPIGNFIPGTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKDKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYT_SULSY
Sequence: MIEIFIEDLNQKFTFNEGITLKDILKNLNGKFKDVVGGKLNGEIIDIHTPINQSGNLKFLKKEDKESLEILRHSLAHIMAQALKEIYGDENVHLGIGPTTEHGFYYDVEIEGKSLTDEDLPQIEEKMKEIIKKGYQIERFELPREEAIKFFENKKEIYKIDIIKHNIPEGEPISLYKQGDFVDLCRGPHLPSTDKAGAFKLISVSGAYWRGKETNPMLQRIYGVAFWSEKELKDYLNMLEEAKKRDHRKIGKDLELFLIDEEIGGGLAIWLPKGAIIRKEIEDAWKKEHLKRGYQLVYTPHVGKEQLWQTSGHLSFYQENMYPRMQIEEEGYYVKPMNCPFHVEIYKSKQRSYKEFPIRLAELGTVYRYERSGALHGLMRVRGFTQDDAHIICREDQVEDEIREVLNLALNTLKSYGFDEFEVYLSTKPEKYVGDDKMWEVAENSLRKAIESTGLDYKIDDGGGAFYGPKIDVKIKDAIGRLWQCSTIQFDFNLPERFDMYYIGEDNQKHRPYMIHRAIFGSIERFIGVLLEHYAGFLPVWLSPVQVKIIPIADKHLEYAETVKQKLLENDIRVELDDRNERMNKKIRDAELQKIPFMLVVGDKEAETGTVAVREKGKQGSQTLSIDEFVSKIKEIISNKHVL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLS_CHIK3
Sequence: MEFIPTQTFYNRRYQPRPWAPRPTIQVIRPRPRPQRQAGQLAQLISAVNKLTMRAVPQQKPRRNRKNKKQRQKKQAPQNDPKQKKQPPQKKPAQKKKKPGRRERMCMKIENDCIFEVKHEGKVMGYACLVGDKVMKPAHVKGTIDNADLAKLAFKRSSKYDLECAQIPVHMKSDASKFTHEKPEGYYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGARTALSVVTWNKDIVTKITPEGAEEWSLALPVLCLLANTTFPCSQPPCTPCCYEKEPESTLRMLEDNVMRPGYYQLLKASLTCSPHRQRRSTKDNFNVYKATRPYLAHCPDCGEGHSCHSPIALERIRNEATDGTLKIQVSLQIGIKTDDSHDWTKLRYMDSHTPADAERAGLLVRTSAPCTITGTMGHFILARCPKGETLTVGFTDSRKISHTCTHPFHHEPPVIGRERFHSRPQHGKELPCSTYVQSTAATAEEIEVHMPPDTPDRTLMTQQSGNVKITVNGQTVRYKCNCGGSNEGLTTTDKVINNCKIDQCHAAVTNHKNWQYNSPLVPRNAELGDRKGKIHIPFPLANVTCRVPKARNPTVTYGKNQVTMLLYPDHPTLLSYRNMGQEPNYHEEWVTHKKEVTLTVPTEGLEVTWGNNEPYKYWPQMSTNGTAHGHPHEIILYYYELYPTMTVVIVSVASFVLLSMVGTAVGMCVCARRRCITPYELTPGATVPFLLSLLCCVRTTKAATYYEAAAYLWNEQQPLFWLQALIPLAALIVLCNCLKLLPCCCKTLAFLAVMSIGAHTVSAYEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELQSVTLEPTLSLDYITCEYKTVIPSPYVKCCGTAECKDKSLPDYSCKVFTGVYPFMWGGAYCFCDAENTQLSEAHVEKSESCKTEFASAYRAHTASASAKLRVLYQGNNITVAAYANGDHAVTVKDAKFVVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAGRPGQFGDIQSRTPESKDVYANTQLVLQRPAAGTVHVPYSQAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAVNCAVGNIPISIDIPDAAFTRVVDAPSVTDMSCEVPACTHSSDFGGVAIIKYTASKKGKCAVHSMTNAVTIREADVEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAACHPPKDHIVNYPASHTTLGVQDISTTAMSWVQKITGGVGLIVAVAALILIVVLCVSFSRH
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. Note=Shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: ALR_LACDB
Sequence: MITAVNRPAALHINLAAIKENTRQAKAHLKPGQKLFCVVKANAYGHGAARLAPVMEEAGADGFCVAMLDEGLELRRAQIVKPILVLGLQPAEESALAAANDISLPVSSLDWLKKAEKVLRKEGLQLKIHLAIDSGMGRIGFSEDEDFKAVNEYLQGNDAFFVEGMFTHFASADSADASYFDYQVKRFKHMESLLTVKPKWIHVDNTAAILFDKDVASDIVRFGIGLYGLNPSSAPGSRDLEPAFALEPAMSFVSELTYVKQIHKGYGVGYGSTHIAEEDEWIGTVPVGYADGWIRKFQGFKVKVGDTYCPIVGRVCMDQFMVLLPKEVPAGTPVELISADPAAPNSLRRAADWLDTIHYEVACQFNDRLDRIYDNE
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ORN_PSEAE
Sequence: MQNPQNLIWIDLEMTGLDPDRDVIIEMATIVTDSDLNTLAEGPVIAIHQPEEILAGMDEWNTRQHGQSGLTQRVRESTVSMAEAEAQTLAFLEQWVPKRSSPICGNSICQDRRFLYRHMPRLEGYFHYRNLDVSTLKELAARWAPQVRESFKKGNTHLALDDIRESIAELRHYRDHFIKL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKF_SALPB
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYTNADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: CCA_BACCQ
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGKMVDLFAGQEAIQKREIMTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKALKELVETKLFSHLPYLQMSEEKLLKATQYKWDSFEADIEAWAFFLYCIGEEHPAVFLRQWKFSNKKIKDIVAVLLTIRKRKEKDWDTVLLYKTGIHIAEMAERVYEAMIESYDHTAVNRVQTLFQALPIKNRQEMNVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: LV1B2_LYCMC
Sequence: MKILAVVLISVIVLNTANGENYYPQKYTNDYYGCQQQTDAFCDKVCKLHLAESGFCDQSWGLAKACKCVNVSYDNSFYFNALESQCPLLNKSAA
What is the function of this protein?
The monomer edited version, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Lipolysis-activating peptide 1-beta chain, LVP1-beta.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BCL2_ORYSJ
Sequence: MAQCGGGDVSRHRKGHLDTVESLCQGLLDDVMLDDDKCRAMFGYLQEWQDLASMCYGSLGGEPPLAPEASNGSGSSGGGGSFRKRRPDDAKGESNSICKRQRGKQQQQQQPCHPDQMAAAVGKGRPERARPGAKKKAEVASPKDSPATSASTVTAGQKTDYIHVRARRGQATDSHSLAERVRRERISERMRYLQELVPGCNKVTGKAGMLDEIINYVQSLQKQVEFLSMKIAASNPVVNFNIVEDLFGRQLSQAACNPAALPAMALPMAQVEPSCLQMSPLQQMQTSAGSSGYGLEMVVSNQYSPPGGPMSVPAGASVEPCLNVNGAAGWDIGSHGLFSGFDAPFQSVQSDCLLDNLKMEM
What is the function of this protein?
Together with BCL1, positive regulator of cell elongation at least partially through increased gibberellic acid (GA) biosynthesis.
What are the official names of this protein?
Basic helix-loop-helix protein 79, OsbHLH079, Protein BC-like 2, OsBC1-like2, OsBCL2.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
Protein: PDP1_YEAST
Sequence: MSPLTRTVAIKKTVKVLSKCQSGREYTQKFLQRAYSTSHANSTYYSRTKLFISSHSKALNIALLSGSLLLTYSYYSPKKILSLDTINGIKDYSTNTSGNINMPSPNPKGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTGIFRYDVAQLPSNHPIEDDHVEQIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALSAGGRKEYVSALVSIPSPMSRRYRDDLTVTVAFFGDSGTPSIVSNATSIVMNPEATTKPKPRL
What is the function of this protein?
Catalyzes the dephosphorylation and concomitant reactivation of the E1 alpha subunit (PDA1) of the pyruvate dehydrogenase complex.
What are the official names of this protein?
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial, PDP 1, Phosphatase two C protein 5, Protein phosphatase 2C homolog 5, PP2C-5, Protein phosphatase of PDH protein 1, Pyruvate dehydrogenase complex phosphatase 1, PDC phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: MQO_MYCSS
Sequence: MSDAQVAKTDVVLVGAGIMSATLSALIKLLEPNWSITLIERLDGAAAESSDPWNNAGTGHSALCELNYTPEGPGGSIDITKAVHVNEQFQVSRQFWTYAVENGVLPDVRNFINPIPHVSFVSGARNVEYLRARYDALVPNPLFATMEYIDDRDEFARRLPFMADKRDFREPVALNWSQDGTDIDFGSLSRQLIGYTAQRGMTTLFGHEVRDLDKQSDGSWSVKVVNRRTGAKRKLNAKFVFVGAGGGALPLLQKAGIEEAKGFGGFPVGGQWLRTGNPELTARHQAKVYGMPPLGAPPMSVPHLDTRVINGKSWLLFGPFAGWSPKFLKQGKVTDLPFSVKPNNLASMLGVGLTEMGLLKYLIGQLLLSEADRVETLRNFAPSARDSDWELDIAGQRVQVIRRKGKGGVLEFGTTVLAAKDGSIAGLLGASPGASTAVPAMLDVMERCFGDRYTAWLPKLKEIVPSLGTKLSDEPKLFQEIWAHGTKVLKLDHPAAGLPVAGTDTEHREPATTVTA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: SYGA_PROM2
Sequence: MFFQDIIKNLNNFWSEEGCLIMQPYDTEKGAGTMNPHTFLRAIGPEPWSVAYTEPCRRPADGRFGDNPNRAQHYFQYQVIIKPSPEGIQEKYLTSLDSLGINPRNHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGIDCKPIPIEITYGLERIAMFLQDKESIWDLNWNRDLKYSDIWLQFEKSQCSYNFKESSADNLRKLFEIYQSEAISLIEKKLTYPALDFVLKCSHNFNLLDARGVISVTDRAQYIEKIRKLAREVASSWIDERESLHFPLMKNSKEIFL
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTJ_CITK8
Sequence: MFYWILLALAIAAEITGTLSMKWASVSNGNTGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDEALSAMKIAGLVTLVFGIALIKSGTRKPVNAAKEATHAAV
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TECR_ARATH
Sequence: MKVTVVSRSGREVLKAPLDLPDSATVADLQEAFHKRAKKFYPSRQRLTLPVTPGSKDKPVVLNSKKSLKEYCDGNNNSLTVVFKDLGAQVSYRTLFFFEYLGPLLIYPVFYYFPVYKFLGYGEDCVIHPVQTYAMYYWCFHYFKRILETFFVHRFSHATSPIGNVFRNCAYYWSFGAYIAYYVNHPLYTPVSDLQMKIGFGFGLVCQVANFYCHILLKNLRDPSGAGGYQIPRGFLFNIVTCANYTTEIYQWLGFNIATQTIAGYVFLAVAALIMTNWALGKHSRLRKIFDGKDGKPKYPRRWVILPPFL
What is the function of this protein?
Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  Required for the elongation of fatty acids precursors of sphingolipids, storage lipids and cuticular waxes.
What are the official names of this protein?
Very-long-chain enoyl-CoA reductase, Enoyl-CoA reductase, AtECR, Protein ECERIFERUM 10, Synaptic glycoprotein SC2-like protein.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: JAGN1_MOUSE
Sequence: MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLLSHDQVAMPYQWEYPYLLSIVPSVLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYRFLFGFSAVSVMYLVLVLAVQVHAWQLYYSKKLLDSWFTSTQEKKRK
What is the function of this protein?
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function.  Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport.  Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
What are the official names of this protein?
Protein jagunal homolog 1.
What is the protein family that this protein belongs to?
Belongs to the jagunal family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL30_AGRVS
Sequence: MAKNTEAQKTITVEQIGSPIRRPAVQRQTLIGLGLNKMHRVRTLEDTPSVRGMIRAVQHLVRVVDEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UBIB_EDWI9
Sequence: MTPSELRRLCLIIRVFLAYGLDELIPLMRITLPLRIGRRCLFWMRNRHGDKPLGERLRLALQTLGPVWIKFGQMLSTRRDLFAPAIADQLALLQDRVAPFDGALARRQIEASLGGPLEQWFDDFDSQALASASIAQVHTATLRENGREVVLKVIRPDIQPIIRADVRLMYRLAGWVPKLLPDGRRLRPREVVREYEKTLLDELNLLREAANAIQLRRNFDASPMLYIPEVFSDYCRESVLVMERIYGVPVSDIAALRAQNTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPQDPQYIGIDCGIVGSLNKADKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNIEEFEFAIRTVCEPIFEKPLDQISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWTTAKPFLENWLHDQVGLPALMRALKAKAPYWSEKLPELPELLYDSLQQQRRLQHSMDSMTHRLGQQGSRQGRARYLFGIGATLLLSGTILTMVNIALWPIGLYVAGGVIWLAGWRYTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PURL_MYCPA
Sequence: MTVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIGGVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACATSELASAGDGGMEVRLEAVPLRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWDVLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQRPLARPDTQDALNADSSARLPRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRGIAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFAQAVRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREKLLAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCEARGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUC15_BOVIN
Sequence: MLTSAKILLISILSSLLLFGSHGEEGQKTNTTESTAEDLKTMENQSVPLESKANLTSDKENRETSNPKASNFSFEDPSNKTHETGFYSNLSTDNSSRSPSLMPTLSPRSPSTHSFVSKLPWNSSIADNSLLPASAPPNTTVPVSSENFTLSSINDTMKAPDNSSITVSNLPSGPNTTSVTPMVTEGWPTTTRESMEGFTVYQETTLHPTLKFTNNSKIFPNTSDPQEENRNTGVVFGAILGAILGASLLSLVGYLLCGKRKTDSFSHRRLYDDRNEPVLRLDNAPEPYDMSFGNSSYYNPTANDSSTSAGGENAHDSIPMDDIPPLRTSV
What are the official names of this protein?
Mucin-15, MUC-15, Component II, Glycoprotein 4, Glycoprotein C, PAS3, PASIII.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: Y2552_PSEAB
Sequence: MDPKLLDILACPLTKGPLVLSEDKTELISKQAGLAYPIRDGIPVMLESEARSLNVDERLDK
What are the official names of this protein?
UPF0434 protein PA14_25520.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: AROB_PYRCJ
Sequence: MRRFYYRHSRGVTEVAVGKRLDYATYAPSPLVLIEEGLPSPLEGPSLRLRGGEEVKSFDSLLRVYQFLAEQGADRSSTLVAVGGGALLDLATFAAGTYMRGIGLVLVPTTLLAMVDAALGGKGAVDVGPVKNLVGVFYQPRAILCDLEWLQSLPDRVYRSALAEVVKYGVALDADFYQWLAENVDEVLRRGERAVEEVVYRSLKIKASIVEVDEFEERGIRQVLNVGHTVGHAVERVFGLLHGEAVSVGIVAELKMAEELGYLTRGTSEEVATLLTRIGLPTCIRASAEELEKAKSLVKFDKKRRGEYVLMPVVVRLGKWVLEKVHVGEVERAVDFVKCSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_VIBCH
Sequence: MENTEKLKNSKEVIAYIAECFPNCFTLEGEAKPLKIGIFQDLADRLNDDPKVSKTQLRAALRQYTSSWRYLHGVKPGATRVDLDGNPCGELEEQHVEHAQAALAESKARVEARRKEQVKKVREEAKANKPKAKKPQQARRPQNAPKVEKKPVETRALAASELNVGNQVNVNMGKGNMAATIVEVNKEDVRVQLANGLQMVVKAEHLRA
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_HAMD5
Sequence: MISAKEIRSKIASVKSTQKITKAMEMVAASKMRKSQESMSATRPYAEMIRKVIGHLALGNLEYKHPYLQERKVKRVGYLVVSTDRGLCGGLNVNLFKKILTDMHDQSEKNVASELSLIGSKGVAFFNSIGAKIVAQVTGISDKPSLPDIIGPVQAMLKAYDEGRLDKLYIANNRFINTMSQQPQITQLLPLLPMDEGQIGVTKKSWDYLYEPEPKVLLDTLLRRYIESQVYQGVVENISSEQAARMVAMKAATDNGGNLIDELQLIYNKARQASITQELTEIVGGASAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.