PharMolix/UniProtQA huggingface dataset:
Protein: SYDND_BORPA
Sequence: MRTCYTGQVCRDHLGQTVTLYGWVNRRRDHGGVIFIDLRDRTGLAQIVFDPDNAEAFGTAERLRNEFCISITGLVRLRPEGTANAELASGEVEVLCQQVEILNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLMLRYRVSIEVRKYLDQLGFIDIETPMLTKSTPEGARDYLVPSRVNAGYFFALPQSPQLFKQMLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLNEVEIREIFEGMIRHVFKVVQDVDLPTPFPIMSWTEAMQRYGSDKPDLRVNLEFTDMTDVMRDVDFKVFASAATTAGSRVVALRVQGGGEMSRSEIDAYTQFVGIYGAKGLAYIKVNDVAKGREGLQSPIVKNLHDAALAELVKRTGAQNGDIIFFGADRAKVVNDAIGALRVKIGHSEFGKKAGLFSGGWKPLWVVDFPMFEYDEEENRYTAAHHPFTSPKDGHEDFLESDPGKAVAKAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIDAEEAREKFGFLLDALQYGAPPHGGIAFGLDRIITMMAGAESIRDVIAFPKTQRAQCLLTGAPSEVDEKQLRELHIRLRNVEVK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_SHESM
Sequence: MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAKGTTTLTNLLDSDDIRHMLASLKQLGVEYRLSQNNTVCELIGLGGAISADTAQTLFLGNAGTAMRPLCAALTLGRGEFTLTGEPRMEERPIGDLVDALKQLGANIVYLKNEGFPPLAINATGLNGGDVEIAGDLSSQFLTALLMVAPLAKDSVNIHVKGELVSKPYIDITLALMAQFGVQVINHDYARFEIPAGQQYVSPGKVLVEGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGAPLTAVDLDMNHIPDAAMTIATAALFAKGTTTIRNIYNWRIKETDRLAAMATELRKVGALVEEGHDYIQITPPAVLNTAEIDTYNDHRMAMCFSMMAFANCGITINDPDCTSKTFPDYFAQFASLKV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1QT1_MOUSE
Sequence: MGSCAQGFMLGCCLLLAITWGPILSLVPRVQEEQQEWEETEELPSPLDPVTRPEETREKYSPRQGEDLPTSRCYRCCDPSTPVYQTIPPPQINITILKGEKGDRGDRGLQGKYGKIGSTGPRGHVGPKGQKGSIGAPGNHCKSQYAAFSVGRKKALHSNDYFQPVVFDTEFVNLYKHFNMFTGKFYCYVPGIYFFSLNVHTWNQKETYLHIMKNEEEVVILYAQVSDRSIMQSQSLMMELREEDEVWVRLFKGERENAIFSDEFDTYITFSGYLVKPASEP
What are the official names of this protein?
Complement C1q tumor necrosis factor-related protein 1, Putative secreted protein ZSIG37.
What are the subcellular locations of this protein?
Secreted.
Protein: XDH_DICDI
Sequence: MIDDENLNGKEPFLKKENQLLFFLNGEKVLINEPNPELSTLDYIRSIGLTGLKRGCSEGACGSCTFMLSNVVKDDNDTFRIVHRAVNGCLYPLCALDGMAVTTIEGLGNIDKGLHSIQERISENSGSQCGFCTPGIIMALYAFLRSNPNSTQKDIEQNFDGNLCRCTGYRPILDAAKSFANQPSDEQLVELPLPPMATIDDKKDDTQMICPGTGKPCNCKTKTSHIPNKPMELNSEPIFPPFLMEYKKESLKFTGSRVTWYTPTTLEELLKIKKEKTNAKIVVGNTEIGIETRFRSIVYPTIICPTRVEELIQIQKEDNGVRVGASVTLTEMKSYLNGIIKSSENDEIANKKNGTFKAIISQLKWFAGNQVRNAASIGGNLCTASPISDLNPVLLAAGAVLTMVSLDDNGAKVRRQVPINQFFLRYRVVDIKPEEILESVFIPYTRPLEFIQAYKQSRRREDDIAIVSCCFRVLLEPIAESASNTVDSNFKIKDCVLAYGGMNVKAVTCEKTEKQLIGSVWSRELLNDACLNLESDLPLAAGAPGGMIEYRRSLTTGFFFKYFLTVSKQLYQISNGNPLYLVSDKEKSATDAYSRPLSFGEQNYQTQPDKHPITQPIKHQSADKQVTGEALYVDDVKMKSLYAVMVPSLKAHANIKSVDASKALKAPGVKAFFSAKDIPGINDCGPVIHDEEVFVTKTALFHGAPIGCIVAETHIQALEASKLVAIEYEELPAITSIEDAISKQSFFPFTHLLKDGDMEKGWSESDHIIDGEFKVGAQEHFYLEPNGTLVIPGEGKELTVISSTQNPTKTQAIVASVLGIGQNQVVCKLKRLGGGFGGKETRSIFSSCVAAIASYHMKEPVRIILDRDTDMSTTGTRHPFIARYRVGFTKEGLIKALDLELYADAGFSYDISVGVLDRAIFHSENSYKIPNVNILGRLCKTNLPSNTAFRGYGGPQAMIICENWVEKISKTLGMDSYKIRELNFYKEAEVTAYRQSVVNNMMKRVWDELMVKSNYHQRLIAVEKFNKENRYKKRGISIIPTKFGMSFTVKTLNQAGALVHVYTDGTILVTHGGTEMGQGLNTKMIQIAARAFNVPVSDVFISETSTDKVPNTAPTAASVSSDLNGMAVLDACQQILLRMEPIREKNPNVPFKQLCTLCFVERVNLSANGFYATPNVGYMFKDSGVGEGTPFNYFNFGAACSEVEIDTLTGDHTTLRSDVILDVGDSLNPTIDIGQVEGAFVQGMGWSTLEEVVTFPSGYMFTRGPSTYKIPGFNDVPIEFNVSLLGDAPNPKAIHSSKGVGEPPLFLGSSVYFAIRQAITAARLENNLTNWFDLQSPATCERIRTSCLDNFVLQFRKQ
What is the function of this protein?
Key enzyme in purine degradation.  Catalyzes the oxidation of hypoxanthine to xanthine.  Catalyzes the oxidation of xanthine to uric acid (By similarity).
What are the official names of this protein?
Xanthine dehydrogenase, XD.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: DNAK_RHORT
Sequence: MSKVIGIDLGTTNSCVAVMDGKDVRVIENAEGARTTPSQVAFTESGERLVGQPAKRQAVTNPENTLFAIKRLIGRRYSDPTVEKDKGLVPYRIVKGDNGDAWVQTRDEKYAPSQLSAFILQKMKETAEAHLGEPVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGMDKKNTGTIAVFDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDARIIDYLASEFKKEQGIDLRTDRLALQRLKEAAEKAKIELSSSMQTEVNLPFITADQAGPKHLNIKLTRAKLEALVDDLVQRTVEPCRKALADAGIKASEIDEVILVGGMTRMPKVQQVVKDFFGREPHKGVNPDEVVAMGAAIQGGVLKGDVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTRKSQTFSTAEDSQTAVTIRVFQGEREMAADNKMLGQFDLVGLPSAPRGVPQIEVTFDIDANGIVNVSAKDKATGKEQAIRIQASGGLSDNDIERMVKEAELNAEADRKRKEAVEARNHADGLIHATEKNLKEYGDKIPAEDKAKVEGDLTALKAVLDSEDAESIKAKTDALMQSAMKLGEAAYSAGQSAEGAPHAAGAEASAQSRTDDGVVDADFEEVDEKKGH
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: VM1AC_CROAT
Sequence: MIEVVLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKELFSKDYSETHYSPDGRKITTNPSVEDHCYYRGRIENDADSTASISACNGLKGHFKLQGELYLIEPLELSDSEAHAVFKLENVEKEDEAPKMCGVTQNWESYEPIKKASDLNLNPDQQNLPQRYIELVVVADHRVFMKYNSDLNTIRTRVHEIVNFINGFYRSLNIHVSLTDLEIWSNEDQINIQSASSDTLNAFAEWRETDLLNRKSHDNAQLLTAIELDEETLGLAPLGTMCDPKLSIGIVQDHSPINLLMGVTMAHELGHNLGMEHDGKDCLRGASLCIMRPGLTKGRSYEFSADSMHYYERFLKQYKPQCILNKPLRIDPVSTPVSGNELLEAGEE
What is the function of this protein?
Snake venom zinc metalloproteinase that causes hemorrhage by provoking the degradation of the sub-endothelial matrix proteins (fibronectin, laminin, type IV collagen, nidogen, and gelatins).
What are the official names of this protein?
Snake venom metalloproteinase atrolysin-C, SVMP, Hemorrhagic metalloproteinase atrolysin C, Hemorrhagic toxin C, HT-C.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y122_HELPY
Sequence: MYRRLLLNLFCMVFLQACLKPMSDPKAEKVDSQVQCGFGSKDC
What are the official names of this protein?
Uncharacterized protein HP_0122.
Protein: RL17_MESM1
Sequence: MANPVQLFRRNSSWQKGVIRSLATDIIIHGRITTTEARAKILRSYVDKLITQAKTDTLASRRRAASFLRNIQLKDGKTSLQYLFASVGPKYKDRNGGYTRIIKLPNRQGDNSKMSIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ILVC_SHEON
Sequence: MANYFNSLNLRQQLAQLGQCRFMDRSEFSDGCNYIKDWNIVILGCGAQGLNQGLNMRDSGLNIAYALRPEAIAQKRASWQKATDNGFKVGTFEELIPSADLVLNLTPDKQHSNVVSAVMPLMKQGATLSYSHGFNIVEEGMQIRPDITVIMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPNGDGLDIAKAYASATGGDRAGVLQSSFIAEVKSDLMGEQTILCGMLQTGAILGYEKMVADGVEPGYAAKLIQQGWETVTEALKHGGITNMMDRLSNPAKIKAFEIAEDLKDILQPLFEKHMDDIISGEFSRTMMQDWANDDANLLRWRAETGETGFENAPVSSEHIDEQTYFDKGIFLVAMIKAGVELAFDTMVSAGIVEESAYYESLHETPLIANTIARKRLYEMNVVISDTAEYGCYLFNHAAVPLLRDYVNAMSPEYLGAGLKDSSNSVDNLQLIAINDAIRHTAVEYVGAELRGYMTDMKSIVGA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GPMA_NOVAD
Sequence: MPRLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAFAAGKLLKDKGVLPTLAFTSLQTRAIKTLHLALEAAGRLWVQEDKDWRLNERHYGGLTGLDKAETAAKHGDEQVKVWRRSFDVPPPPLEAGSEFDLASDPRYDGIAVPATESLKDTIARVLPCWEEKIAPALRAGETVIVSAHGNSLRALVKHLSGISDEDITGLEIPTGQPIVYELDNDLAQVERYYLSER
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: NDK_ECOUT
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEJG_ECOL6
Sequence: MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVALKLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGVAIAEPFSNYNPF
What are the official names of this protein?
Uncharacterized protein YejG.
Protein: FPG_STRMK
Sequence: MPELPEVETTRRGLAPHLQGRRVHGVILRRADLRWPIPPEVAELLPGQRIEDIRRRAKYLLLDTAIGSAVLHLGMSGSLRVLPGDTPLRAHDHVDISLDNGRLLRFNDPRRFGSLLWQPAGEVHPLLQGLGPEPLDDAFDGDYLFARSRGRSAPVKTFLMDQAVVVGVGNIYAAESLFKAGISPLREAGKISRERYQRLADAVKEILGYAITRGGTTLRDFISPDGAPGYFEQELLVYGRDGLPCPNCGRALKHATIGQRASVWCSHCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LEPA_SYNR3
Sequence: MTDAPVSRLRNFCIIAHIDHGKSTLADRLLQDTGTVADRDMQAQFLDNMDLERERGITIKLQAARMQFKAADGELYTLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALGNDLEIIPVLNKIDLPGADAERISTEIEEIIGLDTSNAIHCSAKTGLGVPEILQAIVDRVPAPPDTTEEPLKALIFDSYYDPYRGVIVYFRVVSGRLRKKDKVLLMASKKTYELDEIGVMSPDQKQVDELHAGEVGYLAASIKAVADARVGDTITLASAPAEEPLPGYTEAKPMVFCGLFPTDADQYPDLRDALDKLKLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYKVNMADGSTVMVDNPATLPEPQARESIEEPYVKMEIYAPNSFNGTLMELCQERRGTFIDMKYITTDRVTLQYELPLAEVVTDFFDQMKSRTKGYASMEYSLIGYRQNVLVRLDVLINGDKADPLTTIVHRDKAYGVGKGLVEKLKELIPRQQFKIPLQASIGSRIIASESISAMRKDVLAKCYGGDISRKKKLLKKQAKGKKRMKAMGKVDVPQEAFMAVLKLNENK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RR4_ISOTA
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLRYVHIAGKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKQRSKALIQNYIASSPHEELPNHLTIDPFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: N3009_COPC7
Sequence: MASSDLLSHLSATDRALFWKYGVGAEVSVPFQCVHHAFEFHAKSNPQLTAVDELGTTLSYGELDRRANCLASRLRSVGVVQGSRVCMLVERAVTLPVAVLGILKAGAAYIPLDGNIVSDSTLKHALVDSGSTVALTLRKFEHRLEGAPVPVVFLDDAICPSYNPSHCVKPRDTTTSKDSVYIIYTSGTTGTPKGVHVTHGNVTNLICIEPGQLGMKPGVRVSQMLNISFDFAAWEILGSLANGATLCPRGKTSKDWKAVMRSVDILFSTPSMLAPHNPVDYPNVKTVVVAGEACPKALADTWGARVKFWNACGPTEVTIANTMQLHIPGDIVTIGGPTPNNTAYVLDENMRPVPIGQTGVMWGGGAGITKGYLNLPDKTSERYVRDPFANDGSMMFNTGDLGKWVSNGTLQHLGRIDNQVKIKGFRVELDGVATAMETCAGVTGATALLIDGELWGFVKPSNISPEDIKAAAHKVQPYYAVPSKILTMDHFPETANGKTDKRVLQQMAIESKEEEAKLKEEKAAIPENVAWISLPPTVVTAPKTELTIPHRPSDHSLGSTNTKISAQVKEADSSASSTSELEKQEYIWSGYQDDDHPEKTQGRLVRNLRHQIFSLYRRLFSVVFIVNAAILIWICVKKEYDANRIGGIVIANVFIGVLMRQELVINTFFLIFTSIPSSWPLFIRRTAARVYHIGGIHSGAGVSSLLWLCLFTAQATKEMINGGKTSVRTVAITYVILAELLGIVIFAYPALRKRLHDTFENTHRFLGWSALALVWVQFMFLTIDYLPEGQMLGQTLVKTPQFWLVIILTCSVIWPWFRLRKVDVKPEVLSNHAVRLWFDYVTPPAGTFMRVSDAPLKEWHGFAAIPIPGRTGYSLVVSRAGDWTSKHIANPPTKLWVKGVPTYGVLKLVPMFRRMVIVATGSGIGPCAPAIFEKRIPMRVLWTAPNVRETFGDKLVDSILEANPEAVIYDTRKHGKPDMVKLTLRLVKEFNAEAVAIISNQPLTEKVVYGMMSRGIPAFGAIWDS
What is the function of this protein?
Adenylate-forming reductase, a natural product biosynthesis enzyme that resembles non-ribosomal peptide synthetases, yet serves to modify one substrate, rather than to condense two or more building blocks.  The A-domain preferentially accepts L-serine, L-alanine and L-valine as substrates.  The natural product of the enzyme is not yet known.
What are the official names of this protein?
Adenylate-forming reductase 03009, Alanine/valine/serine reductase, Nonribosomal peptide synthase 12-like enzyme, NRPS-like.
What is the protein family that this protein belongs to?
Belongs to the adenylate-forming reductase family.
Protein: SBCD_ECO57
Sequence: MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLHTLAGEHEA
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: DNLJ_DEHM1
Sequence: MFSPRTEIENLRREINRHNQLYYVQDNPEISDSEYDALLRRLKELEEAHPELVTADSPTQRVGAEPLKAFGIVNHPYPLLSLANAFSDTELEAWYLRVKKLLGNAAFQIDCEPKMDGLAVALTYRNGKFTTGATRGDGFQGENITRNLRTIHSIPLNTEEDAPPVFEIRGEVYLPKEGFAKLNRERADKGLSLFANPRNAAAGSLRQLDPSVTAERPLDIFIYALGYAEDSLLPDSHWQILEYFSRLGFKINPRNRLVNTLEEAKEYYREMAENRDSLPYEADGVVFKVDSVSLQQKLGDAGREPRWAIAYKFPAEQVTTLLRKIGISVGRTGTLNPYAILEPVNVGGVVVKQASLHNEDDILRKDIREGDTVVIQRAGEVIPEVVAPVLAKRSPESKPFSMEETLFNPKLSRPACPVCGGEIYRPAGEAMHYCANVSCPAQFERQLEHFVSRGTMDIRGIGESLSVILAQEGLVKNVSDLYYLTAADLLKLPRMGEKSADNIIKAIADSKSRPLDRVIFGLGIRHVGNETAALLSSRYGDIWALAGAGLDELQTIPDIGAKIASSIKAYFSEEKNIAVIRRLETAGVKLASDQKPSYKPLPLSGVEFVVTGKLDSLSREEAQQKIRSLGGTAKDNVTKATRYLVVGADAGSKLAKARSMGVKELSEQEFINMLEQS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GLMU_ACIBC
Sequence: MSTTVIILAAGKGTRMRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNAKLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPARFDLRGTVKVGHDVRIDVNVIIEGDCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGAVVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNGATVGAGSVITKDVAEQSLSFERAQQISKANYQRPQKLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_SULMU
Sequence: MNAILSDQKTFQAIIRVNQAIEDIRQGKMVVMVDDEDRENEGDLVYAASFSTPQKVNFMASHAKGLICVAISKKIANRLQLEPMVKKNDSSYETAFTITVDARTAATGISAGERDMTIKILADGGSHESELVRPGHIFPLIAKEGGALVRIGHTEGSVDLCRLAGQGDSAVICEIMKEDGTMARRPDLDIFCAKHELNIVYISDIVEYRMMNESLIRVIAESTTQFLGKDARRYDFVDHNDNHHIAYAFGNIKNRSAVKFHSIMPDNELLADTKKYNSLIQAIHYLQKSGGVLIFMDNGTQDMSKIREYGIGAQIIKHLGIENIELLSDSKNKEFVGISGFGLSVIKSTNVNETVA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: VPR_BPP2
Sequence: MLKPDSLRRALTDAVTVLKTNPDMLRIFVDNGSIASTLAASLSFEKRYTLNVIVTDFTGDFDLLIVPVLAWLRENQPDIMTTDEGQKKGFTFYADINNDSSFDISISLMLTERTLVSEVDGALHVKNISEPPPPEPVTRPMELYINGELVSKWDE
What is the function of this protein?
It is proposed that R and S are tail completion proteins that are essential for stable head joining.
What are the official names of this protein?
Tail completion protein R, GpR.
What is the protein family that this protein belongs to?
To phage T4 tail protein GP15.
Protein: GLYA_PORGI
Sequence: MKKDSVIFDLIEKEHQRQLKGIELIASENFVSEQVMQAMGSCMTNKYAEGYPGKRYYGGCEVVDQSEQIAIDRIKQLYGAEWANVQPHSGAQANMAVLLACLEAGDTFMGLNLEHGGHLSHGSLVNSSGILYRPIGYNLSEETGMVDYDHMEKMAIEHKPKLIIGGGSAYSREWDYKRMREIADKVGALLMIDMAHPAGLIAAGLLENPVKYAHIVTSTTHKTLRGPRGGIILMGKDFDNPWGKKTPKGEIKKMSALLDSAVFPGVQGGPLEHVIAAKAVAFGEALDPSFKEYQTQVKKNAAVLAQAFMDKGYKVISGGTDNHSMLIDLRPKFPELTGKVAEKALVAADITVNKNMVPFDSRSAFQTSGFRVGTPAITTRGVKEDKMGYIVELIDRVLSAPEDEAVIASVRTEVNRMMADYPLFAW
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN449_HUMAN
Sequence: MAVALGCAIQASLNQGSVFQEYDTDCEVFRQRFRQFQYREAAGPHEAFNKLWELCCQWLKPKMRSKEQILELLVLEQFLTILPTEIETWVREHCPENRERVVSLIEDLQRELEIPEQQVDMHDMLLEELAPVGTAHIPPTMHLESPALQVMGPAQEAPVAEAWIPQAGPPELNYGATGECQNFLDPGYPLPKLDMNFSLENREEPWVKELQDSKEMKQLLDSKIGFEIGIENEEDTSKQKKMETMYPFIVTLEGNALQGPILQKDYVQLENQWETPPEDLQTDLAKLVDQQNPTLGETPENSNLEEPLNPKPHKKKSPGEKPHRCPQCGKCFARKSQLTGHQRIHSGEEPHKCPECGKRFLRSSDLYRHQRLHTGERPYECTVCKKRFTRRSHLIGHQRTHSEEETYKCLECGKSFCHGSSLKRHLKTHTGEKPHRCHNCGKSFSRLTALTLHQRTHTEERPFKCNYCGKSFRQRPSLVIHLRIHTGEKPYKCTHCSKSFRQRAGLIMHQVTHFRGLI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 449, Zinc finger and SCAN domain-containing protein 19.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA_BEUC1
Sequence: MAELTIKPEEIRAALDSFVNSYEPSASAREEVGRVTLAADGIAEVEGLPGAMANELLQFEDGTLGLALNLDVRHIGVVVLGEFTGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGNPIDGLGDVETEGRRALELQAPGVMARKSVHEPLQTGIKAIDSMIPIGRGQRQLIIGDRQTGKTAIAIDTILNQKANWDSGDPSKQVRCVYVAIGQKGSTIASVRGALEDAGALEYTTIVAAPASDPAGFKYLAPYTGSAIGQHWMYQGKHVLIVFDDLSKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGDAQVKGMKKVSGTLKLELAQYRSLEAFAMFASDLDAASRAQLKRGAALTELLKQPQYSPFAVEDQVAMIWSGTNGYLDDVETADIHRFESELLDHLRRHTSVLDDIASSGLLTDETEEALRNGVESFRRTFAGSDGQIIGGGEPESDGEDVDVEQEQIVRQKRG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VG59_ALHV1
Sequence: METCASFRLSPALLTSSTKIYDHVKSHLKSAMIQFSDLNTTPVMSIISNMGSAGIVTFQLTGAVSDTETLAEITEPLAFRNHSFGGTYLHSREFFGKEIEDILVRFYKRASTASKLPEFVETKITYNNSITETRHTSTVDSHVSPVEKYLQKCFVKAKLILSIKTCTMLQKWLRQNKNKSPVARLHINETLTVLVVTVGDECTTIEFKSFVLEPADAFLTLDKPGNFGAVLVDCTAVVNLECLIQAIGICKVPSVCVPAFKFYSGGIVEVSSAHLKQSKSPSATVSTVLLDASESLKQPAEQEQPTTSQPSDPQSSNSVDKPSPPRPSISQPVRRRAPPRAIISDSEEDSDSDSDQDCSTETQPETSYREEPKKFTPKPTAPPNKRKQFEPLKCPVEKKKKSNSNSFVSII
What is the function of this protein?
Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template.
What are the official names of this protein?
DNA polymerase processivity factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase accessory subunit family.