PharMolix/UniProtQA huggingface dataset:
Protein: DRG2_MOUSE
Sequence: MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGRGRGRQVIAVARTADVVVMMLDATKGDVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDDFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK
What is the function of this protein?
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP.  When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
What are the official names of this protein?
Developmentally-regulated GTP-binding protein 2, DRG-2, Translation factor GTPase DRG2, TRAFAC GTPase DRG2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RPOC_STRPM
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSAEAVFTAEAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NSP5_ROTJ1
Sequence: MSEVPRFELRSKRKIGKKQKVDIFGDKDDESMLQIDCETDSLISESVSSTHSYEDYSKAYKELTLETPADVNDSASTIVDSVCEESWYDKTIKDEQTKEDKKTDKKLKRIEKVKENNQNDSMSLQIAQLSLRIQRIESETKLKTLDSAYNTIITQADNLTTPQKKSLISAILATMR
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HSP70_THEPA
Sequence: MTGPAIGIDLGTTYSCVAVYKDNNVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQEARNPENTIFDAKRLIGRKFDDRTVQEDMKHWPFKVTNGPNGKPNIEVTFQGEKKTFHAEEISSMVLTKMKEIAEAFLGKSVKDVVITVPAYFNDSQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKGGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNLLVEHCVRDFMRLNNGKNISSNKRALRRLRTHCERAKRVLSSSTQATIELDSLYEGIDYNTTISRARFEELCNEKFRSTLVPVEKALESSGLDKRSIHEVVLVGGSTRIPKIQTLIKNFFNGKEPCRSINPDEAVAYGAAVQAAILSGNQSEKIQELLLLDVAPLSLGLETAGGVMTVLIKRNTTIPTKKNQIFTTNEDRQEGVLIQVFEGERAMTKDNNLLGKFHLTGIAPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKSEHVTITNDKGRLSQEEIDRMVEEAEKYKEEDEKRRKCVESKHKLENYCYSMKNTLSEDQVKQKLGADEVDNALNTITEALKWVETNQLAEHDEFEDKLKHVEGVCNPLVTKLYQSGGAPGAGPDMGAGFPGGAPPPSSSSGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein, 70 kDa heat shock protein, HSP 70.1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y386_LIMRD
Sequence: MVDKKLKVVIITGMSGAGKTVAVHSLEDLGYFVIDNMLPGLAERFVDVIEDSREFDKIAMVMDMRSRGFYDEVLPNFEKLKKRADLDVKLLFLDANDVTLISRYKETRRSHPLSPQGRILDGVELERKLSTDLKSQADIVIDTTNVTPRNLKLRLNKLFGHGEGNDFYVEVMSFGFKYGLPLDADIVMDVRFLPNPFYIPELKHLTGNDPAVQNYVMQSPLAKEFYQHLRSLLEIALPGYIKEGKSSLTIAIGCTGGQHRSVTIANKLSADLKEKGYKVNTYHRDIEKAK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Lreu_0386.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CDNF_RAT
Sequence: MRCTSPAALVTFCAGLWISNHVLAQGLEAGVRSRADCEVCKEFLNRFYNSLLTRGIDFSVDTIEEELISFCADTKGKENRLCYYLGATKDSATKILGEVTRPMSVHMPTVKICEKLKKMDSQICELKYEKKLDLESVDLWKMRVAELKQILHSWGEECRACAEKHDYVNLIKELAPKYVETRPQTEL
What is the function of this protein?
Trophic factor for dopamine neurons.  Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons.  When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
What are the official names of this protein?
Cerebral dopamine neurotrophic factor, ARMET-like protein 1, Arginine-rich protein mutated in early stage tumors-like 1, Conserved dopamine neurotrophic factor.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPAB_ASPUT
Sequence: MAVAPNVSDLQSGVVKASQMARAALEHTLQHHQLQDFILAAILASIILLIIRNSMLSPLRGIPGPRLAGLTSLYEFYYDVIKNGTYAHQHPKMHQQYDSTIIRISPNHVHIADPELFAIGPAGSRFRKARYYYNSIGMSTAIGSHYDVEAHHRHRSTMAVGFSTKSLQAFDPIIVNYAREIMDIIASRGLKGTPVVLSHHTQAYTIDVVAKISFGQPVGAMHEVGDHPPTVQAMDCFSNHFNFTKHFPYWQLILPFMPTSAVKRIMPGVHYIKEVGTRLITNLIEQRRIEGRLDEEYQEGKGAIFETLLKPNPKKQYPAPDLNGLVEDACAFLVGGSDTTGLTLQAVTLFVLRNPDVLCALRAELDSASEFIRDSFDIHQVSKLPWLTAVIRETMRLLPPTPGPLPREVPPEGIRVGKYFLPGGNANKGPGRQPGDAEFRPLSPAVCSLYITIPASTQTQKGSSRSVGWEKAVRAWWSGGTHSVVDHARVSDASTSCAYFVFSSSIICGREQHTDERFLACRVAWHELLAFLALLFLRFDLELYESDETNLEWTEHMFTRIRAPVQVRIMKDRWA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of oxepinamides, derivatives of anthranilyl-containing tripeptides that share an oxepin ring and a fused pyrimidinone moiety (PubMed:33004788).  The nonribosomal peptide synthetase (NRPS) opaA assembles the quinazolinone core with D-Phe incorporation (PubMed:33004788).  The first adenylation domain (A1) of opaA loads and activates anthranilic acid whereas the second A domain (A2) is for activating of L-Phe, which is then converted to D-form by the E domain (PubMed:33004788).  The third A domain (A3) is responsible for L-Ile activation and the terminal condensation domain C3 for cyclization and releasing the NRPS product protuboxepin K (PubMed:33004788).  The cytochrome P450 monooxygenase opaB then catalyzes alone the oxepin ring formation to convert protuboxepin K into protuboxepin A (PubMed:33004788).  The flavoenzyme opaC installs subsequently one hydroxyl group at the oxepin ring, accompanied by double bond migration, to form 15-epi-oxepinamide E (PubMed:33004788).  The epimerase opaE changes the D-Phe residue back to L-form, leading to oxepinamide E, which is further methylated at the hydroxyl group at C-12 by the O-methyltransferase OpaF to yield oxepinamide F (PubMed:33004788).
What are the official names of this protein?
Cytochrome P450 monooxygenase opaB, Oxepinamide F biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KCY_XANCB
Sequence: MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDEAGEAGLRVLVNGVDATGELRLETTGALASAIAAIPEVRSALKERQRAFRQPPGLVADGRDMGTVIFPDAAFKVFLTASAEERAGRRHKQLMEKGVSVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGIGIEDVVQRVVGLLDSRTP
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_CAMJE
Sequence: MLNTLLVVGFGGFIGAILRMLSINLVNKFFPYSISFGTLFVNVLGSFIIGLLFSYAQNKGLSPLLKSFISTGFLGAFTTFSTFSYQNLLLLQSGNYLHFALNIILNVFLCLFAAWLGFLIFK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YE034_YEAST
Sequence: MEGASEFFFLFSFISHAMMLTGLIGSSSFLEGDGGFFTHSGDDGNHQVLTFIKSSLQTVTQFTFWSLDIILSVTVHVHQRQETVINVQQLVFVSLDNWNFHVVSRWRQIFQLLTSEDINGNQMDFSVTVLTSLRSGHVDNLTWSTLDDNETVLSQGRTLHWVGGGGTSVSSFKGMFFVRHCIYELVFVCVWESMSNWLQK
What are the official names of this protein?
Putative uncharacterized protein YEL034C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ASSY_HAHCH
Sequence: MSKVNKVVLAYSGGLDTSVIVKWLQENYDCEVVTFTADIGQGEEVEPARAKAEKLGVKQIFIEDLREEFARDFVFPMFRANTIYEGEYLLGTSIARPLIAKRLVEIANETGADAISHGATGKGNDQVRFELGAYALKPGIKVIAPWREWDLTSREKLLTYCDTHDIAVEKKKGKSPYSMDANLLHISYEGGILEDPWEEAEEDMWRWSVSPEAAPDQATYLELTYQNGDIVAIDGEALAPHEVIERLNKVGGVNGVGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDKELAHLKDSLMPKYAELIYNGYWWSPERLALQKLIDESQQHVNGVVRVKLYKGNVIVAGRKSEDSLFDDRIATFEDDGGVYNQRDAEGFIKLNALRMRIAADKGRSMK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK2A_DICDI
Sequence: MNHSSKKNKNRILRNKARIYCDVNLHKPKEYWNYEALNVKWETQDDYEIIRKIGRGKYSEVFEGANIKNNEKCVIKVLKPVKKKKIKREIKILQNLCGGPNIITLYDVVRDPQSKTPSLIFEYINNTDFKHLSPTLTDFDVRYYIRELLHALDFCHSNGIMHRDVKPSNVMIDHQKRKLYLIDWGLAEFYHPNQDYNVRVASRPYKGPELLVDMEDYDYSLDMWSLGCMFAGMLFQKDPFFHGHDNIDQLVKIVKILGTEEFYAYLDKYGIVVDHTILSIIGKHPKKPWSRFITKENQHLAVPEAIDFLEKLLRYDPAERLTTREAMEHPYFKPLSH
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  The alpha chain contains the catalytic site.
What are the official names of this protein?
Casein kinase II subunit alpha, CK II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CK2 subfamily.
Protein: FMT_PSEA6
Sequence: MKSGLKIVFAGTPEFAANHLSALIESEHQVIAAYTQPDRPAGRGKKLHASAVKQLAQQHDIPVYQPASLKSEEAQQQLAALNADVMVVVAYGLILPQIILDTPKYGCLNVHGSLLPKWRGAAPIQRAIWAGDAETGVTIMQMDKGLDTGAVLSELRLAITPIDTSATLYTKLAELGPKGLLETLASLGDLTPQAQDNTLATYAEKLSKQEAKIDWTMTAAQLERNVRAFDPWPVAYFEANGAAIKVRSAEVQQTPICDNAKPGQIIQADKHAIGVQTGDGVLLIKTLQLPGKKPLATQDILNGHSDWFSVGTILS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YR073_MIMIV
Sequence: MQSTDISTNKIKFTVDKFNYVVKLSVLKNTHKITIKCTHNEEFYCWTFMTCEIIKSDYSSNSFYYDSSNSSINENINDENSNFLSINICPEMLFNILTAFKNNMLDKIYQINFPQDFDSVKSNLSILLTITLPLMNNFPDIKTIILEPKNINEPKRCSLKLMRQSFIIQQKNNEKFEKLSEKIEKMGKELTELQTVHNGLVKYIKEKYVRLDDLVDFVNKRDIDVITQVKKN
What are the official names of this protein?
Uncharacterized protein R73.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R73/L269/L862 family.
Protein: GPMA_HAES1
Sequence: MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKAAGKKLLEAGYEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVKHWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDVSPPDLDPQDPNSAHNDRRYALLPKDVVPNAENLKITLERVLPFWEDQIAPALLSGKRVLVTAHGNSLRALAKHIIGISDEEIMAFEIPTGQPLVLKLDEQLNFVEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: TRKA_MYCTO
Sequence: MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAHWRLGDACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVVARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEFRTGQANLVEITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIVPEADEPLEGGDELLFVAVTEAEEELSRLLLPSM
What is the function of this protein?
Part of a potassium transport system.
What are the official names of this protein?
Trk system potassium uptake protein TrkA, K(+)-uptake protein TrkA.
Protein: RL36_THEP1
Sequence: MKVQASVKKRCEHCKIIRRKKRVYVICKVNPKHNQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RPC9_MOUSE
Sequence: MEVKDANAALLSNYEVFQLLTDLKEQRKESGKNKHSAGQQNLNAITYETLKYISKTPCRNQSPAIVQEFLTAMKSHKLTKAEKLQLLNHRPMTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAGPEDEQSKSTSNDVAMEEEEPA
What is the function of this protein?
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor.  It modulates CGRP responsiveness in a variety of tissues.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC9, RNA polymerase III subunit C9, Calcitonin gene-related peptide-receptor component protein, CGRP-RCP, CGRP-receptor component protein, CGRPRCP.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BIOF_SYNY3
Sequence: MATGSTAYTWLDDALETIQRAHWHRHPQIITQGPGPEIKLEGQRLVNFASNDYLGLASHPHLKTAAIKAIAEWGTGSTGSRLLSGHRQLHQDLEQAIARWKGTEAALVFSSGYLANLGTITALVGKRDLILADEYNHSSLKRGAQLSGAKVINYDHGCPEVLTDLLMKHRDNHRRCLILSDGVFSMDGDLCPLPQLVAIAEEFQSMLLVDDAHGTGTMGKMGTGCREHFQLPVGDWIQVGTLSKALGSLGGYVAGSASLIDFLRNRAATWIYTTGLSPADTAAALAAIQLIQREPERIVQLQLNVDYLATGLESLTKLNFRRSPINSPILWVGAANPAMALEMAKHLREQGIFAPAIRPPTVPHSRIRFSVMATHSPGHIDQLLEVLDHYYPN
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: HIS6_ALIB4
Sequence: MSSFAKRIIPCLDVDNGRVVKGVNFVGLRDAGDPVEVAKRYNSEGADEITFLDITASHENRGTIVDIVKKVAQEVFIPLTVGGGIRKLEDIYSLLNVGCDKVSINSSAVTNPNLINESSKRFGSQCIVVAIDVKRVADGSYHVFVKGGREDTGLDALSWAKEVYDRGAGEILLTSMDTDGAKTGFELNITRQVSNLVDIPVIASGGAGSMEHIKEAFENGASAALAASIFHFKEIDIMDLKKYLRANNIPVRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZP06_ORYSJ
Sequence: MAQLPPKIPVAAPGHHQHWASAGGAGDAAWADEFAEFAASRRGAHRRSLSDSVAFVEVAPAGCGAGGEFDRLDDDQLMSMFPDEGGSSAPGSDNGGSDSDGGGDKHAAAQSDDGQHAAGEPTQEQAAATSPTELIRDPKRVKRILANRQSAQRSRVRKLQYISELERSVTTLQNEVSVLSPRVAFLDQQRTILTVGNSHLKQRIAALAQDKIFKDAHQEALRKEIERLRQVYQQQNTKLSGGLAADHAHVHGGPPPVRAEKELMS
What is the function of this protein?
Transcription regulator.
What are the official names of this protein?
Basic leucine zipper 6, OsbZIP06, bZIP protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_BORHD
Sequence: MSYVPELKRHYKDNVIKELVSEFQYKSIMQAPKIEKIVVSMGVGDAVKNKKLLDSAISELSQITGQRAVKTKAKKAIAGFKIRQGQDIGAKVTLRGNIMYEFLYKLINLALPRVKDFRGVDGNAFDGNGNYSFGIAEQIIFSEIDYDKIERISGLNVTIVTTALNDKEGKALLSKFGMPFSN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CARB1_AQUAE
Sequence: MPKRTDIKKILIIGSGPIVIGQAAEFDYSGTQACKALKQEGYEVILVNSNPATIMTDPEMADKTYIEPLTADILEEIIKKERPDALLPTLGGQTGLNLAVELYENGVLERYGVELIGANYEAIKKGEDRELFKETMESIGLKVPESAVVRSVEEGLKAVEKIGFPVILRPAFTLGGTGSSVAYNVEEFKEKLKVALETSPIHEVLLDKSLIGWKEIEFEVVRDKADNVIIVCAIENFDPMGVHTGDSITVAPTQTLTDKEYQMLRDAAIAVIRAIGVDTGGSNIQFALSPESGDFYVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELKNDITKFTPASFEPSIDYVVVKIPRFDFAKFPEADRTLTTMMKSVGEVMAIGRTFKEALLKAVRSLELDRYGLAFPKLTNVDKVELERNLINPNDQRLWYIAEAFRRGYSVDEVYELTKIDRWFLYNIEEIVKFEEVLRKEELTPEILRQAKEMGYSDWEIAKIKGITEEEVRKLRKEEGIVPTFKGVDTCAGEFVAYTPYYYSSYERPYYTVDGQEILDED
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, N-terminal section, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MMM1_SCHJY
Sequence: MVQLFHLTFTQGFFIGQLSVIVIVYIFLRFFLFCTKEELKNVQEESYPLSPSNEKSTTEFNDATHKVTPSLSEIYDVKTHEEESLDWFNVLVAQALSQIRQDAVSDDAALKKLQTLFNGKRKPSFLGPIHIKSISLGQRYPVFSNCRIQAQPDDTNGLRATMDLSLEDDIHFVVNTSAVLNVPRPAFAMLPVSLSVRIVHIRGKLSIYFSQSSKSAKRAYLNFTFDPDFDMGIEIQSLVGSRSKLQDIPKIAHIIETRIRKWFITRCVSPQFQQISIPNIWPSSAREGHRQKSTE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: TRPR_SALPK
Sequence: MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLEQILLKSA
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_CUPNH
Sequence: MLNALYPLVRPALFSMDAEDAHHFTLNNLLRAHRMGLAGCIGNRIADDPRTVMGVRFPNPVGLAAGLDKDGAYIDGLAAFGFGFIEVGTVTPRAQPGNPRPRMFRLPQADALINRMGFNNGGVDAFVANVRASRWKAEGGVLGLNIGKNADTPIERANDDYLYCLERVYPHASYVTVNISSPNTKNLRQLQGASELDSLLSTLKDAQQRLADQHKRYVPLALKIAPDLDADQIGNIGDALVRHKIDGVIATNTTISREAVKGLPHAEEAGGLSGRPVFEASTRVVRALHGVVGDAVPIIGVGGIFGGADARAKIDAGAKLVQVYSGLIYRGPALVRECAAALRG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPH_PROMA
Sequence: MDTQAFKRSLHHSDRYNRRGFESPAKRAQALEKAYQSNLIASIRDNGYLLEHGRLRVKLAEAFGFCWGVERAVAMAYETRRHYPTESIWITNEIIHNPSVNDHLRNMNVRFISAEKGIKDFSSVEEGDVVILPAFGATVHEMKLLHERGCHIIDTTCPWVSKVWHTVEKHKKHEFSSIIHGKVKHEETLATSSFAGTYLVVLDLKEAQYVSDYILGKGNRDDFLRRFSRASSQGFDPDRDLKRLGVANQTTMLKSETEEIGRLFEKTMLRKYGPAELNEHFLAFNTICDATEERQDAMFSLVDEPLDLLVVIGGFNSSNTTHLQEIALAKGIRSFHIDTPERIGEIENTITHKPLGDDLRVESNFLPEGKINVGITSGASTPDRIVEHVIQKLINLSERKLMTEN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RS7_UREP2
Sequence: MRKLKPQKRQVLADPVYNSRLVTKLINAIMYDGKKGLAQSIIYSAFEIVEQKTGKPALEVFNKAIDNVMPIIELKVRRVGGSNFQVPTEVTPERRQTLGLRWITLYARLRHEHTMIEKLAHEIIDASNNVGAAIKKKEDTHKMAEANKAFAHLRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.