PharMolix/UniProtQA huggingface dataset:
Protein: SPEE_PROM9
Sequence: MTHISTWIDEYHKGSRFGLNGEILIKQNSKYQEIIVIENEYYGRALMLDGCWMTSLKDEKYYHECLVHPALSSIDEKSNVLIIGGGDGGTARECVKYPQISKIDLVEIDEEVIKISKKFLKEIGGEAWSDKRLKIHIDDGVQWVKKTRDNFYDVIFIDCSDPSELSNLLFSDSFYRECKRILTKNGILATQSESPESFKNIHISILKTLKKFFRVSETMYSFVPIYPSGIWSWTFASEEVLHLSKRNCNEALRIEKSCEIWNLNFQNAAFKMMPNKIVKELNS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLEB2_ECOLR
Sequence: MLSPIRTTFHNSVNIVQSSPCQTVSFAGKEYELKVIDEKTPILFQWFEPNPERYKKDEVPIVNTKQHPYLDNVTNAARIESDRMIGIFVDGDFSVNQKTAFSKLERDFENVMIIYREDVDFSMYDRKLSDIYHDIICEQRLRTEDKRDEYLLNLLEKELREISKAQDSLISMYAKKRNHAWFDFFRNLALLKAGEIFRCTYNTKNHGISFGEGGIYLDMDMILTGKLGTIYAPDGISMHVDRRNDSVNIENSAIIVNRSNHPALLEGLSFMHSKVDAHPYYDGLGKGVKKYFNFTPLHNYNHFCDFIEFNHPNIIMNTSQYTCSSW
What is the function of this protein?
Protein-arginine N-acetylglucosaminyltransferase effector that catalyzes the transfer of a single N-acetylglucosamine (GlcNAc) to a conserved arginine residue of host target proteins.  In contrast to NleB1, not able to disrupt TNF signaling in infected cells.  Shows a lower enzymatic activity than NleB1.
What are the official names of this protein?
Protein-arginine N-acetylglucosaminyltransferase NleB2, Arginine GlcNAcyltransferase NleB2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase NleB family.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via the type III secretion system (TTSS).
Protein: RRG8_YEAS6
Sequence: MGLPKSAYKKLLIDCPTRVINKNCAQRVKDVSPLITNFEKWSDKRKKLYFKDEEEMVGHFHLENFNLKNNLYGRLLASPMRAEKISKLKSCRELLIPLKVVPSTGKDQHADKDKLKLVPTLDYSKSYKSSYVLNSASIVQDNLAAATSWFPISVLQTSTPKSLEVDSSTFITEYNANLHAFIKARLSVIPNVGPSSINRVLLICDKRKTPPIEIQVVSHGKGLPITQSVFNLGYLHEPTLEAIVSKDAVTKGIYLDADNDKDLIKHLYSTLLFQSVN
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG8 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DUT_BRADU
Sequence: MSTKVTVELQRLPHAEGLPLPAYQTAEAAGLDLMAAVPEDAPLTLASGRYALVPTGLAIALPPGHEAQVRPRSGLAAKHGVTVLNSPGTIDADYRGEIKVILINHGAAAFVIKRGERIAQMVIAPVVQAALVPVATLSATDRGAGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL9_ECO24
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TRPB2_AQUAE
Sequence: MRKFLLSEGEIPKKWLNILPLLPEPLEPPLDPETMEPVKPEKLLAIFPEPLVEQEVSDKEWIDIPEEVLDIYSLWRPTPLHRAKNLEEFLGTPAKIFYKNESVSPPGSHKPNTAVAQAYYNKISGVKRLTTETGAGQWGSALSFATQFFDLQCRVYMVRVSYNQKPYRRILMETWKGEVIPSPSPYTNAGRKYYEENPEHPGSLGIAISEAIEEAASREDTKYSLGSVLNHVLLHQTVIGLEAKKQMEEAGYYPDVIIGAVGGGSNFAGLSFPFLADVLRGDKRKEDLKVLAVEPEACPTLTKGEYKYDFGDSVGLTPLIKMYTLGHDFVPSPIHAGGLRYHGDAPLVCKLYNLGYIDAVAYKQTEVFEAAVTFARTEGIVPAPESAHAIKAAIDEALKCKETGEEKVILFNLSGHGYFDLSAYDKYLHGELTD
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RS8_SINFN
Sequence: MAMTDPLGDMLTRIRNGAARRKSSVSTPASKLRARVLDVLQAEGYIRGYSEVEFGNGKAELNIELKYYEGASVIREIARVSKPGRRVYVSVKSIPQVANGLGITILSTPKGVMADHQAREQNVGGELLCSVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PDS5B_MOUSE
Sequence: MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYSLQSAAGKDAAKQISWVKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEALVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDTKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTANVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKREDPDLSELEKPRSRKKAPVTDPEEKLGMDDLTKLVQEQKPKGSQRGRKRGRTASDSDEQQWPEEKRHKEELLENEDEQNSPPKKGKRGRPPKPLGGGTSKEEPTMKTSKKGNKKKLVPPVVDDDEEEERQIGNTEHKSKSKQHRTSKRAQQRAESPETSAVESTQSTPQKGRGRPSKAPSPSQPPKKIRVGRSKQVATKENDSSEEMDVLQASSPVSDDTTQEGAEEEDISVGNVRRRSSKRERR
What is the function of this protein?
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin.  May couple sister chromatid cohesion during mitosis to DNA replication.  Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.  Plays a role in androgen-induced proliferative arrest in prostate cells (By similarity).
What are the official names of this protein?
Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3.
What is the protein family that this protein belongs to?
Belongs to the PDS5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPLD_THESW
Sequence: MRYTDGKVHDITIAYIGGGSRGWAWNLMTDLAKEESISGTVKLYDIDYDAAHDNEIIGNALSMRQDVKGKWLYKACETLEESLKGADFVIISILPGTFDEMESDVHAPEKYGIYQSVGDTVGPGGIVRALRTIPMFVDIANAIKEHCPDAWVINYTNPMTLCVRTLYEIFPQIKAFGCCHEVFGTQKLLSRALQDIEGIENVPREEIKINVLGINHFTWIDNARYKDIDLMYVYKQFVNKYYESGFVSDANNNWMNNSFVSAERVKFDLFLRYGVIAAAGDRHLAEFVPGYWYLKDPETVREWMFGLTTVSWRKEDLKRRLERSKRLKTGEEKFELKETGEEGVRQIKALLGLGDLVTNVNMPNHGQIEGIPYGAVVETNALFSGNKLKPVLSGKLPDNVNSLVLRQVYNQETTLKAALKRDFDLAFSAFVNDPLVTISLKDAKKLFKEMLENTKKYLDGWKIKA
What is the function of this protein?
Alpha-galacturonidase able to catalyze the hydrolysis of the chromogenic substrate p-nitrophenyl-alpha-D-galacturonic acid (pNPalphaGalUA).  It is probable that alpha-1,4-di-galacturonate (GalUA(2)) is the naturally occurring substrate.
What are the official names of this protein?
Alpha-galacturonidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: MAO1_ENT38
Sequence: MDKKTKKHRSLYIPYAGPVLLEFPLLNKGSAFSAEERSSFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVQNHLEEMMPVIYTPTVGAACERFSEIYRRSRGVFISYENRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLTDPLYMGWRHPRVTDDEYYQFVDDFIQAVKHRWPDVLLQFEDFAQKNAMPLLNRYRDEICSFNDDIQGTAAVTAGTLIAASRAAGSQLSYQKIVFLGAGSAGCGIAEQIIAQTQREGLSEELARSRVFMVDRFGLLTDAMPNLLPFQTKLVQKRENLKNWDTDNEVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCERPIVMPLSNPTSRVEATPQDIIVWTEGNALVATGSPFDPVIWKDKVYPIAQCNNSYIFPGIGLGVIASGASRITDEMLMSASETLAQHSPLVKNGEGLVLPELKDIHIVSRAIAFAVGKMAQQQGVAVKTSADALQQAIDENFWMPEYRSYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RS16_PROM9
Sequence: MIKLRLKRFGKKKEASFRIVACNSTSRRDGRPLQELGFYNPRTKETRLNTEALRIRLTQGAQPTDVVRNLLEKGGLLEKKERPSIAIGKAKLEKEKVAKAKIKNEENDSSKAESDSNEAES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS3_GEMAT
Sequence: MGQKTNPIGFRLGVTKNWRSTWYAKKEMPALLKEDALLRKYLKARLDNAAIADVTIERKPGKVVVTVHTGRPGVVIGKKGAEVDKLRDELAQLTGKEVGINVEEIKRPEVEAQLVADNIAAQLSQRISFRRAMKRAVQSAMRMGALGIKVKAGGRLGGAEIARVEGYMEGRVPLHTLRADINYATSTAKTTYGTIGVKVWIFKGEIVEDRRGKTYSTGN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DNLJ_STRPI
Sequence: MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELETAYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHPTYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDITVRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVVIKVNDLVSQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIPTNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFAANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGSKASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFAAEGSEILLRELKETGVNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVVVGADAGSKLQKAQELGIQVRDEAWLESL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ACP_EXIS2
Sequence: MTKEQILVDVQEAIAEKLGKEQSEITLDKSFKDDLGADSLEVMELVMDLEDKFEITIEDDQAENLKTVGDVVSYIETQV
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_RUBXD
Sequence: MPFRVEVLNETSGGARLTPERATELCRRAFVERGLDPERMGELSVALVEPEVIHDLNLKFRNKDAPTDVLSFEVDGPYGEMVGEIVICPGCAEMDLEELVVHGALHLSGMDHGENFEASEMARVQKRVMEAVRGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYBA2_ORYSJ
Sequence: MVTVREEIRKGPWTEQEDLQLVCTVRLFGERRWDFIAKVSGLNRTGKSCRLRWVNYLHPGLKRGRMSPHEERLILELHARWGNRWSRIARRLPGRTDNEIKNYWRTHMRKKAQERKSNMSPSSSSSSLTYQSCHPETPSMIIGIEEQELHGGSGCITSIMKSTPVDMDGYPMDQIWMEIEAPNVLPGPCFDEAKDSASNSLSGPLLPYPMWDYYCPETCLRMDDEIKVAPQFGYGKGVGPCY
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
Myb-related protein MYBAS2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENO_CAUVN
Sequence: MTEIVDIIAREILDSRGNPTVEVDVILEDGAFGRAAVPSGASTGAHEANEKRDGDKARYLGKGVQQAVDAVNGEIFDALSGVDAEDQRRVDNLMIELDGTPNKARLGANAILGVSLATAKAAAESAGLPLYKYVGGVNARVLPTPMMNIINGGAHADNPIDIQEFMILPTGAKDFREGLRMGAEIFHALKKALKDAGHNTNVGDEGGFAPNLASAEAALDFIVKAGEKAGYKAGDDFVLGLDVASTEFFKNGKYELEGEGKSLDPAAMVDYLAGLVAKFPILTIEDGMAEDDFDGWKLLTDTLGKKVQLVGDDLFVTNPKRLQMGLDKGLANSILVKVNQIGTLSETIDAVELAHRHGYTSVMSHRSGETEDSTIADLAVALNCGQIKTGSLARSDRTAKYNQLLRIQEMLDDQGVYAGRAALKGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: XGPT_DESVH
Sequence: MSTADRYRKVFPVTWEQLHRDAKALSWRLLEKGPYKGIIAIARGGLVPAAVIARELDIHLVETICISSYQWQEQTSSHKVLKTVEGRGEGWLIIDDLADTGGTARLVREMLPEAHFATVYAKPAGRPLVDTFITEVSQDTWILFPWDSEVQYVVPLVNQPQQS
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KAX63_HETSP
Sequence: ASCRTPKDCADPCRKETGCPYGKCMNRKCKCNRC
What is the function of this protein?
Potently blocks voltage-gated potassium channels Kv1. 1/KCNA1 (IC(50)=7-11 nM) and Kv1. 3/KCNA3 (IC(50)=11-29 pM) (PubMed:9359871, PubMed:24676092, PubMed:15498765).  Also mildly blocks intermediate (IK) conductance calcium-activated potassium channels (KCa3. 1/KCNN4) and ERG1/Kv11. 1/KCNH2 (PubMed:18687312, PubMed:15498765).  Shows ability to suppress proliferation of lymphocytes, which are known to be sensitive to Kv1. 3/KCNA3 homotetrameric channel block (PubMed:24676092).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.3, Neurotoxin HsTX1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y116_ADE02
Sequence: MERRVWFLSRSARSLAAMFSCTYSRATHRHSGKTVVRSSGTRCTRQPRLCRVTRSTLVATSPRRRSLVQQRRPPLREQNGGSGSSCVSSGGSASTVKTPGSRRASK
What are the official names of this protein?
Uncharacterized 11.6 kDa early protein.
Protein: INO1_YEAST
Sequence: MTEDNIAPITSVKVVTDKCTYKDNELLTKYSYENAVVTKTASGRFDVTPTVQDYVFKLDLKKPEKLGIMLIGLGGNNGSTLVASVLANKHNVEFQTKEGVKQPNYFGSMTQCSTLKLGIDAEGNDVYAPFNSLLPMVSPNDFVVSGWDINNADLYEAMQRSQVLEYDLQQRLKAKMSLVKPLPSIYYPDFIAANQDERANNCINLDEKGNVTTRGKWTHLQRIRRDIQNFKEENALDKVIVLWTANTERYVEVSPGVNDTMENLLQSIKNDHEEIAPSTIFAAASILEGVPYINGSPQNTFVPGLVQLAEHEGTFIAGDDLKSGQTKLKSVLAQFLVDAGIKPVSIASYNHLGNNDGYNLSAPKQFRSKEISKSSVIDDIIASNDILYNDKLGKKVDHCIVIKYMKPVGDSKVAMDEYYSELMLGGHNRISIHNVCEDSLLATPLIIDLLVMTEFCTRVSYKKVDPVKEDAGKFENFYPVLTFLSYWLKAPLTRPGFHPVNGLNKQRTALENFLRLLIGLPSQNELRFEERLL
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (Ref. 6, Ref. 8, PubMed:23902760, PubMed:14684747).  Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).
What are the official names of this protein?
Inositol-3-phosphate synthase, MIP synthase, Myo-inositol 1-phosphate synthase, IPS, MI-1-P synthase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MYCGE
Sequence: MLNSRFPVSVKKSHSLRERKVFTTILQSKTRFFGTFINAYFIKNNHSTWRVAISIAKTKYKLAVQRNLIKRQIRSIFQQISNNLEPWDILVIVNKGFIELTFKEKQKLFLQLLKRIKEVDAYQTSANK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ALMT7_ARATH
Sequence: MEKVREIVREGRRVAKEDPRRVVHSFKVGLVLALVSSFYYYQPLYDSFGVNAMWAVMTVVVVFEFSVGATLGKGLNRVAATLFAGGLGIGAHHLASMSGPTGEPILLAVFVFVQAALSTFVRFFPRVKARYDYSLLIFILTFALISVSGFREEQVVKLTHKRISTVIIGGLSCVIISIFVCPVWAGQDLHSLIASNFEKLSFFLLGNSFHYVSSDLNSITLLRKIKSWRLADFGDKYCEVVENDGAKEVDKRKKDFDNYKSVLNSKSNEESLANFAKWEPGHGQFRFRHPWKQYLAVGELIRQCAYRIHALNSYLNADNQVSVDIKKKLGEPLRRMSLESGKAMKEMSISLKKMTKPSSSDLHVQNAKSACKSLTNLLNSGILKEVEPLELVSLLTAISLLIDIINLTEKILESLHELATAAKFKNKIEHPLFSEKPKAKSFVSVRSIKCHDDHVVIIIEDDGNNDDTSKNDNGSKEVSIHEKHEDDDTHVDARCVSCGHTSVCVK
What is the function of this protein?
Malate transporter.
What are the official names of this protein?
Aluminum-activated malate transporter 7, AtALMT7.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter (TC 2.A.85) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARGP_SHIBS
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: KCRB_RAT
Sequence: MPFSNSHNTQKLRFPAEDEFPDLSSHNNHMAKVLTPELYAELRAKCTPSGFTLDDAIQTGVDNPGHPYIMTVGAVAGDEESYDVFKDLFDPIIEDRHGGYQPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLSGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWINEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKNYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPHLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQPIDDLMPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.  Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.  During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work.
What are the official names of this protein?
Creatine kinase B-type, B-CK, Creatine kinase B chain, Creatine phosphokinase M-type, CPK-B.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Note=Localizes to the mitochondria of thermogenic fat cells via the internal MTS-like signal (iMTS-L) region.
Protein: H2A1_ORYSJ
Sequence: MAGRGKAIGAGAAKKATSRSSKAGLQFPVGRIARFLKAGKYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELTKLLGGATIASGGVMPNIHQHLLPKKAGSSKASTVDDDDN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYM_ALCBS
Sequence: MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADDAHGTAIMLKAEENGVTPEQQIAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQRNKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSEDQYGDNCEVCGATYTPAELIEPYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISREAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGKDIINFHGLFWPAMLDGAGLRKPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYLRYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASRTGNFVKKFGGTLSTELDNMMLVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAICSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVDMAQVESMLEDSKESTPAPAAAKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAHVDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLVVLVANLAPRKMKFGISEGMVLAAGPGGDDIHILSPDSGAEPGMEVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_FRATT
Sequence: MSFIPHKLEQIKKMLDTIGASSVDQLFDEIPRHLRADTLKIKDGINEIQLANLMRKRANKNHHNINYIGAGAYSHHIPAAIWDIVARGEFYTAYTPYQAEASQGGLQVIYEFQTMMAGLTGMDASNASMYDGATALAESVLMAIRSNKKAKSQKVLIAEALHPTYLRVLETITKHQGIEFDIVNLDSKNGKTDVTKLEDFANTNYAAVVIQSPNFLGQLADVDGITNWAHKHGALVIAVTNPMSLAILKSPAEWGDNGADIVCGEGQPMGVPLASGGPYFGFMTCKMAHVRQMPGRIVGRTVDLDGNEGFCLTLQAREQHIRRAKATSNICTNQGLMVTAATIYMSLLGAEGLERVASISHENTQTLATELAKINGVSIRFNSAFFNEVVIDLPVNAETFVTEMEKEAIDAGYFLGEYHSDLANSIMVCATEIHTSEDIKEYIEATKKVLARIGG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.