PharMolix/UniProtQA huggingface dataset:
Protein: NDHH_CARPA
Sequence: MNIPATGKDFMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELVYDLFEAATGMRMMHNYFRIGGIAADLPHGWIDKCLDFCDYFLTGVAEYQKLITRNPIFLERVEGVGIIGGEEAINWGLSGPMLRASGIEWDLRKVDHYECYDEFDWEVQWQKEGDSLARYLVRISEMTESIKIIQQALEGIPGGPYENLEIRCFDRKKDPEWNDFDYRFISKKPSPTFELPKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y24K_STRGR
Sequence: MPCTHCRTPNGTSSSATWRTARPAPRRCGSCRPPPPGSASPSPRPRRASCATGCCGRSRPYARRLRRPADGHGPAGGGRTGRWYAYALAACVAAAAAFGGVAVWQNQVAQDARQQANQAQRQNERLAQVLSAPDAKTASSELTGGAHGTVVVSQSQNRAVFLASGMAPPPSGKVYQIWFNDEGTMRSAGLMDPKASDDAVLLNGPVDRASGMGITVEPAGGSAEPTSDPVALMNFPTA
What are the official names of this protein?
Uncharacterized protein in phr 5'region.
Protein: UBC2_KLULA
Sequence: MSTPARRRLMRDFKRMKEDSPPGVSASPLPDNVMIWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVYANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFQDHKSQYVKRVKETVEKSWEDDMEDMADEDEDEE
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.  Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 2, E2 ubiquitin-conjugating enzyme 2, Ubiquitin carrier protein UBC2, Ubiquitin-protein ligase UBC2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MEND_BACCR
Sequence: MNNHIEALSYYLGAFVDELTRLDVCDVVISPGSRSTPIALLMEQHEGMNTYLHVDERSAGFFALGIAKAKKRPVALLCTSGTAAANYYPAVCEAFHSRVPLIVLTADRPHELRDVGAPQAMNQFNLYGTFVKQFTEMALPEASEAMYHYARMTTQRIVANACLAPQGPVHLNFPVREPLIPDFSLESLWDKGRSEYTGVVQQGNAVMPSEYVDSLVGRLSHMEKGLIICGDDSHAEIAMFATQLAEKTGYPILADPLSNIRSGHHDKTMVIDCYDTFLRNEKLKETWNGDVLIRFGGMPVSKSLTQFIKKQTKAVHIVVDESGQWRDPALVATEVVQASDIEFCKAAIEKMPVMKKNDWSLMWQHINEKTKETLREMETYETAFEGKVITDIVRVLPEDATLFASNSMPIRDTDSFFFTSDKNIHVMANRGVNGIDGIISTALGASVICDPLVLVIGDLSFYHDLNGLLAAKLHELNITIVVVNNDGGGIFSFLPQYEKKEHFESLFGTPIGLDYEHVVKMYGGSFSRVNGWEQFREEVRKGTTTEGLHVVEICTNRDENLTLHRTLWAKTMDVITTSLQGESK
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: LPRM_ENTFL
Sequence: MLVFQMRNVDKTSTVLKQTKNSDYADK
What is the function of this protein?
This peptide is involved in the control mechanism of the synthesis of the erythromycin resistance protein.
What are the official names of this protein?
23S rRNA methylase leader peptide, Erythromycin resistance leader peptide.
Protein: NUSG_ECOL6
Sequence: MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVSVSIFGRATPVELDFSQVEKA
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.  In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing.  In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho.  May be required to overcome a kinetic limitation of Rho to function at certain terminators.  Also involved in ribosomal RNA transcriptional antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: CH60_STRMU
Sequence: MAKDIKFSADARSSMVRGVDILADTVKVTLGPKGRNVVLEKSFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIETAVATAVDELKAIAQPVSGKEAIAQVAAVSSRSEKVGEYVSEAMEKVGNDGVITIEESRGMETELDVVEGMQFDRGYLSQYMVTDNEKMVADLENPYLLITDKKISNIQDVLPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDTTIDALGQAARVTVDKDSTVIVEGSGGKEAVANRVNLIKSQIETATSDFDREKLQERLAKLSGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALINVIEKVAALDLTDDAATGRNLVLRALEEPVRQIAKNAGYEGSVIIDKLKNSSAGTGFNAANGEWVDMIDAGIIDPVKVTRSALQNAASVASLILTTEAVVADHPAPEAPAAAPAMDPSMMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_GRAFK
Sequence: MRHGKKINHLGRQTAHRKAMLANMACSLIEHKRINTTVAKAKALKVFVEPLVTKCKNDTTHNRRLVFSKLRSKEAVSELFREVAPKVGDRPGGYTRVIKLGSRLGDAAEMALVELVDFNETYNVGEKPKKKKSTRRAGKKKTEDTASTAEPKEASAKETKKEEPKAKEPKAEEKKDDKKEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RNH2_STRZJ
Sequence: MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAIQAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKGLNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSPQPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDFATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBY4_YEAST
Sequence: MIKAWFDTNKYVAMHMQTEPFVYIKIICIKEEERPHNSTHTHTHTLSHTQFEIAPIGLGNRITSHSKYTIFSITHTHCIKPFVSKKYKNTAQRAVSGSICDCLFFFWFSSVQNEGSKNFQIKQYSSPEICFRV
What are the official names of this protein?
Putative uncharacterized protein YBR134W.
Protein: SYH_BACFN
Sequence: MAAKPGIPKGTRDFSPVEMAKRNYIFNTIRDVYHLYGFQQIETPSMEMLSTLMGKYGEEGDKLLFKIQNSGNYFSGITDEELLSRNAAKLASKFCEKGLRYDLTVPFARYVVMHRDEITFPFKRYQIQPVWRADRPQKGRYREFYQCDADVVGSDSLLNEVELMQIVDTVFTRFGIRVCIKINNRKILTGIAEIIGEADKIVDITVAIDKLDKIGLDNVNKELAEKGISGEAIAKLQPIILLSGTNAEKLATLKTVLSDSETGLKGVEESEFILNTLQTMGLKNEIELDLTLARGLNYYTGAIFEVKALDVQIGSITGGGRYDNLTGVFGMAGVSGVGISFGADRIFDVLNQLELYPKEAVNGTQLLFINFGEKEAAFSMGILSKARAAGIRAEIFPDAAKMKKQMSYANVKNIPFVAIVGENEMNEGKAMLKNMESGEQQLVTAEELIGALTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANF_DICDI
Sequence: MKNFYYFILILLFFNEVCYSLKDGEIKLHLIPHSHCDSGWTSTMNEYYMGQVKSIISSMVQSLNVESNPPRKFVWSEIGFLEQWWDDMPIEIKNDFIKHVKNDRIEFVNGGWVMNDEACASLESVIRQLSNGHKFIREKFGKQPESGWQIDPFGHSSLTPTLQAQFGYKHVVLNRIHYELKKKFKEEKNLQFKWRGSPEGVGPKSDILAHVFDDFYTSPPHMSFDGYNFLAYGLPRLTMEMIELARNRSVFYKSPHVLIPMGGDFAFKNAYKSFEQMDQLVASINGQHANGESNVICQYSTLADFFSDTINWHNENKVSFNYYDSDFFPYADDSNTYWTGYYTSRPLLKGYERHVSSKLRSAEILSALQNDEKYYPNQLLNASKQVSILQHHDAISGTSKKHVVQDYFSRLQKADILVSEQSEKLLASALSQHSPTKLDIIDIGGSLNFPKNNDAISFILFNQLSWSKEELISIKVQSVGDHGESLNSPTNNACPYVLAQEDFLNEIEIDCSPRSDFKSDQSDDHKEFIQIDFPAKLKPFSSKLYYLKRKSNPNKSNWVLPKTNHFNSIENSIYTANLDENYLIKSLKSKSSRHGGGANQITEINQQLLTYSDIGGAYIFRTNKQVFQPPRQVYSTFTYIGKFYQEAQSILQDTHQISNRNGYYYYYGNNQQQQQQQQTISTFNYNSIKLINTGNEMIDKKINFNFHIRGINGTTTINRFTTDIDNNRELYSDNGLEMMHRKSISSQSVEVGRETQSYYPTINSVYIESQSTGKRFVCNNDRSRGVSSQGQGCLEMALHRSLTYEDGKGLEIPAIDESSINARFECYLDEVPSNSQQSNGGGGGDDIRKQSINYQHKFQIYQGQDSSYMSSKSFMLKPLPEFIHILSMERSGPRSIKLRIHNIENNNQSPITFDLNGLFSFIKSIKSIKEYNLSLINRFVDNNIDNIISSHRSIVGKNLFPIKDTPTRFNPINTKQTKITLYPSEIKAIEITYH
What are the official names of this protein?
Alpha-mannosidase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_EHRRG
Sequence: MSRRRRANKRVITPDSKYNSVLLARFINVIMRSGERSIAEKIVYGALSKAENRIGESAMSVFSSALNNVMPQMEVRSRRIGGVTYQVPVEVKEDRSVSLALRWISRAAATARKRSNKMYMDCLCNELLEAYNKRGGAYKIREEKYKMAEANKAFSHFRFN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ALR_STRP4
Sequence: MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVEGIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: KPTA_ECO8A
Sequence: MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLILCAQKAGKRLTRALLDTVVATSDKKRFSHSSDGRCIRAVQGHSTSQVAISFAEKTPPQFLYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKRGIPFWQAENGVWLTSTVAVEFLEW
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: Y1721_LISMC
Sequence: MNLETPSQENLNFMLTEITTKLKMVNVGVFENLELDSVDYNALIDIYQLIKRKSNFSPREMQLFAEELRRIRK
What are the official names of this protein?
UPF0435 protein Lm4b_01721.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: COBT_CERSK
Sequence: MKAPFTSLAGFRAVFETLPQVDAEAVEAATARNETLTKPKGALGRLEDLAIWYAGWIGDGRPALERPQVAIFAGNHGIAARGVSAFPPEVTVQMVANYRAGGAAVNQLCHVAGASMTVTELELDRPTLDFTVSPAMTEDELVAALAAGWEAVDDESDLLVVGEMGIGNTTAAAAIAAALFGGTAAEWTGRGSGVAGSALEAKTRVVAEGLERHGDALSDPLEVLRCLGGREIAAMAGAIARARVGRTPVILDGFICTSAAAVLHALTPSALDHAIAGHVSAEGAHPAALARIGKEPLLDLGMRLGEGTGAIVAINILRSAVACLSGMATFAEAGVSGG
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL10_SHEPA
Sequence: MALGLEDKKAIVAEVNEAAKGALSAVVADSRGVTVANMTGLRKAAREAGVYIRVVRNTLVKRAVAGTDFECLSDTFTGPTLIAFSSEHPGAAARLLKDFAKAQEKFEIKAAAFEGELIPAENIDRLAKLPTYEEALAQFMMTLKEASAGKFVRTLAALRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL1_OENOB
Sequence: MVKKHSKKYLAAAEKIDHSKKYSLADAATLVKDISFTNFDSNVEVVFDLNVDTTKADQQLRGAIVLPNGSGNPKTVVVFADGEKAKDATQAGADFVGTDDLIQKVQSGWTDFDVAIATPDQMAKVGRVGRALGPKGLMPNPKEGTVTMDVTKAVSDAKGGQVTYRTDKNGNVAVPVGKVSFDSDKLAENIKSVSSTILGARPSTVKGTYVLSAHLASTMGPGVELDVSSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PDXA_YERPG
Sequence: MHNHNNRLVITPGEPAGVGPDLAITLAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTILPVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATEELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQGINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFITALNLAIKMINNSNE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1B_AERPE
Sequence: MARVAVVVKVYPDDVSIDPKTLAERIKSKLPSGYEVLAEGEEPIAFGLKALKLVIAMNEDTEGGTEEVEQLLKNIEGVQEVEVENVSRMQ
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: GATA_METMA
Sequence: MMAKWMSVAQVKEKIKESSAEEVTSRYLEVIKKSKINGYLTISDKALEQAKKIDKEGHEGPLAGVPIAIKDNISVVGLPNSCGSKILEGYVPPFNAHVIEKLLSAGAVILGKTNMDEFAMGSSTETSHFGPTANPWDLERVPGGSSGGSAAVVAAGEAPFALGSDTGGSVRCPASFCGVVGLKPTYGAVSRYGVVAYANSLEQVGPLANNVEDIAVLMDVIAGYDRRDSTSIDSKTEYQKALVDDVKGLKIGVPKEFFGEGIHPDVEKAVWDAIHKCESLGATWEEVSMPHIKYALASYYIIAMSEASSNLARFDGTRYGFRAGGENWHAMVSKTRAEGFGTEVKRRILLGTYALSAGYHDKYYLKALKVRTLVKQDFDKALSKVDLLMAPTMPNPAFKIGEKIEDPLTLYLSDINTCPINLAGVPSISVPCGFTDGLPIGLQIMGKPFDEETVLRAAYTFEKNTDYHTKRPPEVA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RGYR_SACSH
Sequence: MINVMYKNSCPNCGGDISADRLLNGLPCETCLPYINGIDGIDHISKVKALYNILLDNDKIKNYWNLYYNITTFETVFKYFKDKTGYEPWSLQKLWLRRLVSNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKVDQRKVSVITISYLNKNADSITSYKPNFVAIDDADAVIKSGKTTDRLVSLLGIPNDVYESAIQLIRLRNKYYFSNEFTEEIKEKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDTYTDNLDLSIIKELGSGGLILVSKEYGRSRLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIKAKLFDALSNPFTLLRVGKMIGVNFSELQNKILVLSPSEAQLLKFSIIKGETINYQKLEQLRQELLYYISLVKDKLKEIGEETLISDNFVIAKQNTNYYIIYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDKHIFEILKKKMQKLFPNTNFTSLSNINLSEIKTKLEESRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRVINKVPVYETIIVDGNQIYVLDVVASKGHIVDLTLEDIGYYGIKIEYSGIIKPYYDLIKKCLDCNKTFSIASDKCPYCGSTNVQTAQTTINLLRELALSVDKVFIASDPDTEGEKIAYDLASFLSPYNSNIYRITYHEITKKAILEALRNPMKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQTPVLGWIVDKTIKYKSAMGYVVYIDIAGYPIKMHFSERKKMEEYINNLQVVKIEKIFEEKILLSPLPPFTTDTLLIEANMKYKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQGLIKDFVPRSWESSEEGAHEAIRPTRAIDVNELIQEIEENPYKYSIRFSKLHFLIYDLIFRRFMASQMSHAVGTKSRYLIKLNKNDNINAELLSNAEGGFIKVYPVKVYNLPLGEVKPKVNTGKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLVRHGYIVSSKRKSYLIATNRGISAYQFLSSKFYDLVSEGTTAKLMSKLDDIALSKLSASTVLLEIFSEISTLVNPLKSEQNV
What is the function of this protein?
Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process.  It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue.  May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
What are the official names of this protein?
Reverse gyrase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
Protein: DAPA_BRUSU
Sequence: MLKGSITALVTPFDREGAFDEKAFRAFVNWQIEEGTKGLVPVGTTGETPTLSHDEHKRVIEVCIEVAAGRVPVIAGAGSNNTVEAIELAQHAEKAGADAVLVVTPYYNKPNQRGLYEHFSRVVRSISIPLVIYNIPGRSIIDMTPETMGALVRDCKNIVGVKDATGKIERVSEQRAICGKEFIQLSGEDATALGFNAHGGVGCISVTSNIAPRLCAEFQEACQAGNFAKALELQDRLMPLHKALFLEPNPSGPKYALSRLGRIENVLRSPMVTIEAATAEKIDHAMKHAGLIN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_GALGR
Sequence: MTNIRKQHPLAKMINHSFIDLPAPSNISSWWNFGSLLGLCLMIQIITGLFLAMHYTSDTTTAFSSVTHICRDVNHGWIIRYLHANGASMFFICLFMHIGRGLYYGSFTFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYMGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPSGISSDSDKIPFHPYYTIKDLLGVILLLLSLFSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLIPLPHTAKQASMMFRPLSQCLYWMLVADLLILTWIGGQPVENPFIIIGQTASIIYFFIILILMPLTNLLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRMN6_ECOLC
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_SALAI
Sequence: MLLRMSTLLLRTLREDPADAEVPSHRLLLRAGYLRRAAPGGYTWLPLGKLVLDRVAEVIRTEMLAIGDQEVHFPALLPAEPYRTSGRWTEYGDDLITLVDRRGAEHLLAPTHEEPAALLVKELFTSYRDFPVGIFQIQTKFRDEARPRAGLLRGREFLMKDAYSFDLDEAGLQAAYDRHRSAYQKIFARLGLDYAVVHAVSGAMGGSASEEFLATSKIGEDVYVGCTACDHTANTEAVTTLAPPASNPEERPATQVHDTPDTPTIASLVGLANARALAGRDDWAAGDTLKNVVLTIRPPGAAKSELLVIGLPGDREVDLKRVAATLAPATVTVFDGWADHPELVRGYLGPQVMAKLGVRYLVDPRVVPGTAWLTGANEPGRHATNVVCGRDFLPDGTIEAAEVRPGDPCPACRTGQLTLRRGIEIGHIFQLGRRYTDAFTVDVLGPEGQSVRPTMGCYGIGVSRAVAVIAEQHHDERGLVWPTEVAPCDVHLVAAGRGPQVETALGLGNRLAEAGLRVLVDDRGHVSAGVKFTDAELVGIPRTVVVGRRLADGYAEVRDRPSGKRADVRVDALVEHLVNEVHSG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_MICLU
Sequence: MLTDLHKVRNIGIMAHIDAGKTTTTERHLFYTGVNHKLGETHDGGATTDWMEQEKERGITITSAAVTCFWNDHQINIIDNPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSETVWRQADKYDVPRICFVNKMDKLGADFYFTVDTIVKRLGARPLVMQLPIGAENDFVGVVDLISMKAFVWPGDANGIVTMGASYEIEIRQLQEKAEEEYRNELVEAVAETSEELMEKYLEGEELTVEEIQAGVRQLTVNAEAYPVFCGSAFKNRGVQPMLDAVVAYLPNPLDAGPVKGHAVNDEEVVLEREVSKEAPFSALAFKIATHPFFGTLTFIRVYSGRLESGAQVLNATKGKKERIGKLFQMHANKENPVDEVVAGHIYAVIGLKDTTTGDTLCDPANPIILESMTFPEPVISVAIEPKTKGDQEKLSTAIQKLVAEDPTFRVNLNEETGQTEIGGMGELHLDVFVDRMKREFKVEANVGKPQVAYRETIKRKVDKVDYTHKKQTGGSGQFAKVQLSFEPLDTPRGTVYEFENAITGGRVPREYIPSVDAGIQDAMKFGVLAGYPMVRVKATSLDGAYHDVDSSEMAFRIAGSQAFKEGVRKATPIILEPLMAVEVRTPEEFMGDVIGDLNSRRGQIQIQSMEDATGVKVVNALVPLSEMFGYIGDLRSKTQGRAVYSMTFHSYAEVPKAVADEIVQKSQGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.