PharMolix/UniProtQA huggingface dataset:
Protein: GLYA2_MYCTU
Sequence: MNTLNDSLTAFDPDIAALIDGELRRQESGLEMIASENYAPLAVMQAQGSVLTNKYAEGYPGRRYYGGCEFVDGVEQLAIDRVKALFGAEYANVQPHSGATANAATMHALLNPGDTILGLSLAHGGHLTHGMRINFSGKLYHATAYEVSKEDYLVDMDAVAEAARTHRPKMIIAGWSAYPRQLDFARFRAIADEVDAVLMVDMAHFAGLVAAGVHPSPVPHAHVVTSTTHKTLGGPRGGIILCNDPAIAKKINSAVFPGQQGGPLEHVIAAKATAFKMAAQPEFAQRQQRCLDGARILAGRLTQPDVAERGIAVLTGGTDVHLVLVDLRDAELDGQQAEDRLAAVDITVNRNAVPFDPRPPMITSGLRIGTPALAARGFSHNDFRAVADLIAAALTATNDDQLGPLRAQVQRLAARYPLYPELHRT
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.  Thus, is able to catalyze the cleavage of L-allo-threonine.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHM2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1002_GLAP5
Sequence: MANLSPDEAIELAYDIFLEMASDNLEPADILLFNLQFEERGAVEMVETSENWEQEIGVLIDPDAFAEVWIGLINQNDEMDDIFARFLISNDAENREYHVIWKS
What are the official names of this protein?
UPF0263 protein HAPS_1002.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: PAND_MYCUA
Sequence: MLRTMLKSKIHRATVTQADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYGTMQDAEARAYQPRIVFVDADNKQIDVGHDPAFVPAFDIPGAEELLNPRIGAR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF91_ARATH
Sequence: METKKISYFLLPSLMIVALIFQPMCSAFTIAEPYIHPCMKGFCSFKSECANKCIFMGHHKGGDCIGGLDGIYCCCLA
What are the official names of this protein?
Defensin-like protein 91, Low-molecular-weight cysteine-rich protein 47, Protein LCR47.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: VAPB1_HAEIN
Sequence: MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the effect of toxin VapC1 (By similarity).
What are the official names of this protein?
Antitoxin VapB1.
What is the protein family that this protein belongs to?
Belongs to the VapB family.
Protein: TP8L2_PAPAN
Sequence: MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAVKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLTECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKLLDEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits JUN/AP1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: DDL_HELAH
Sequence: MVEFCVLFGGASFEHEISIVSAIALKEVLKDQIKYFIFLDENHHFYLIEASNMHSKYFAQIKEKKLPPLMLTHNGLLKNSFLGAKTIELPLMINLVHGGDGEDGKLASLLEFYRIAFIGSRVEASVLSYNKHLTKLYAKNLGVKTLDCILLNEKNRANALDLIKPSFNFPFIVKPNNAGSSLGVSVVKEEKELAYALDGAFEYSKEVLIEPFIQRVKEYNLAGCKIKEDFCFSYVEEPNKQEFLDFKQKYLDFSRTKAPKANIPNALEEQLRENFKKLYNDLFDGAIIRCDFFVIDNEVYLNEINPIPGSLANYLFDDFKTTLENLAQSLPKTPKIQVKNSYLLQIQKNK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFB_SHESH
Sequence: MSGIFIAIILLTILALLFGILLGFAAEKFKVEGDPLVDQLEALLPQTQCGQCGYPGCRPYAEAIANGEKINLCPPGGSATMEKLAEMAGVEPEPLSATEEVQVKKVAYIREEECIGCTKCIQACPVDAILGSGKLMHTVITDYCTGCDLCVAPCPVDCIDMLPVEQTVKNWDWKLNAIPVKTLDEDCQC
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: ILVC_STAA1
Sequence: MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PPNP_ACIBS
Sequence: MSSTQFDHVTVIKKSNVYFGGACISHTVQFEDGTKKTLGVILPTEQPLTFETHVPERMEIISGECRVKIADSNESELFRAGQSFYVPGNSVFKIETDEVLDYVCHLEG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: SYE2_THEPX
Sequence: MSEVRVRFAPSPTGSLHIGGARTALFNWLFARHNGGKFILRVDDTDLQRSTEESMKGILEGLKWLGIDWDEGPIYQSQRLEEYRKFANKLLKEGKAYYCFCTKEELEEMRKQAEKEGRPPMYTGKCRNLTKEQIEEYLRQGKKPVIRLKVPQQGKTVVHDIIRGDVEFDNSTFDDFIIMKSDNMPTYNFATVVDDYQMGITHVIRAEEHLSNTPKQILIFEALGLEIPQFAHVSMVLAPDRSKLSKRHGATSVQEFRDQGYLPEAIVNYITLLGWIPKDGEEIFDVSKSIKEFTLERVSKNPAIYDVQKLTWINGHYIRNYDLDKLTEVVIPFLKAKNFIGEDFDYDYIKKIVSVVREREKTLVDVADAMSYYFTEVNEYEEKGVKKYFTKEKVVDILKKAVVTLKEVEPFNKFTTEETYRKLVEELQISSGELFHPTRLAISGRTFGPGLFDIMELLGKERTIKRIEKAIDFIQKMRK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDIR1_BOVIN
Sequence: MAEQEPTAEQLAQIAAENEEDEHSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVAVSADPNVPNVVVTRLTLVCSTAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYNIKSRFTDDDRTDHLSWEWNLTIKKEWKD
What is the function of this protein?
Controls Rho proteins homeostasis.  Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.  Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation.  Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms.  Through the modulation of Rho proteins, may play a role in cell motility regulation.  In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
What are the official names of this protein?
Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI alpha.
What is the protein family that this protein belongs to?
Belongs to the Rho GDI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_HAHCH
Sequence: MARRKKGAPLNGVMVVDKPQDWTSNAVLQKVKYALNAQKAGHTGALDPLATGVLPLCFGEATKFSQLLLDSDKEYVTCAYLGRTTTTSDADGDIIAESPVPGLSVSDLESVLGKFRGNLKQIPSMYSALKHKGTPLYKLARQGIEVEREARDIIIHELELLDYTPPFLRLRVLCSKGTYIRNLVEDIGQVLGCGAHVMELRRTRCGPFSLADSVEFVSFADESGRQAAAEKYKERLLPIDSSVQQFSEIILDEANTGSIIQGQTVKISPLSSEGKVRLYTNRRHFIGLGEVMSDGTVKPVRLLNVSALSAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: VWC2L_DANRE
Sequence: MGPFLPAICVVLLALNAAVSPASVGPEDYPAADEAERTANNDIIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYRGKTYKILEEFKPSPCEWCRCEPNNEVHCVVADCAVPECVNPVYEPEQCCPICKNGPNCFAGTTIIPAGIEVKVDDCTICRCHSGDWWKPAQCLRRECLNGQATS
What is the function of this protein?
May play a role in bone differentiation and matrix mineralization (By similarity).  May play a role in neural development.
What are the official names of this protein?
von Willebrand factor C domain-containing protein 2-like.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: RL4_BACHK
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: OSTA_HUMAN
Sequence: MEPGRTQIKLDPRYTADLLEVLKTNYGIPSACFSQPPTAAQLLRALGPVELALTSILTLLALGSIAIFLEDAVYLYKNTLCPIKRRTLLWKSSAPTVVSVLCCFGLWIPRSLVLVEMTITSFYAVCFYLLMLVMVEGFGGKEAVLRTLRDTPMMVHTGPCCCCCPCCPRLLLTRKKLQLLMLGPFQYAFLKITLTLVGLFLVPDGIYDPADISEGSTALWINTFLGVSTLLALWTLGIISRQARLHLGEQNMGAKFALFQVLLILTALQPSIFSVLANGGQIACSPPYSSKTRSQVMNCHLLILETFLMTVLTRMYYRRKDHKVGYETFSSPDLDLNLKA
What is the function of this protein?
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:16317684).  Efficiently transports the major species of bile acids (taurocholate) (PubMed:16317684).  Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity).  Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (PubMed:16317684).  Able to transport eicosanoids such as prostaglandin E2 (By similarity).
What are the official names of this protein?
Organic solute transporter subunit alpha, OST-alpha, Solute carrier family 51 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the OST-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B (By similarity). Mainly restricted to the lateral and basal membranes of ileal enterocytes.
Protein: WHB2A_MYCTU
Sequence: MVPEAPAPFEEPLPPEATDQWQDRALCAQTDPEAFFPEKGGSTREAKKICMGCEVRHECLEYALAHDERFGIWGGLSERERRRLKRGII
What is the function of this protein?
The apo-form functions as a chaperone, preventing aggregation or helping in correct refolding of a number of substrates; this activity does not require ATP or the ability to bind a Fe-S cluster.  Chaperone activity is insensitive to the redox state of its cysteine residues.  The apo-form has no protein disulfide reductase activity.  The apo-form binds to its own promoter.
What are the official names of this protein?
Transcriptional regulator WhiB2, Probable chaperone WhiB2.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAL1_CHLRE
Sequence: MAKATTIKDAIRIFEERKSVVATEAEKVELHGMIPPIEKMDATLSTLKACKHLALSTNNIEKISSLSGMENLRILSLGRNLIKKIENLDAVADTLEELWISYNQIASLSGIEKLVNLRVLYMSNNKITNWGEIDKLAALDKLEDLLLAGNPLYNDYKENNATSEYRIEVVKRLPNLKKLDGMPVDVDEREQANVARGG
What is the function of this protein?
Part of the multisubunit axonemal ATPase complexes that generate the force for flagellar motility and govern beat frequency (PubMed:19620633).  Component of the outer arm dynein (ODA) (PubMed:19620633).  May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (ODA2) to the A-tubule of the outer doublet microtubules within the axoneme (PubMed:22157010, PubMed:10353837, PubMed:19620633).
What are the official names of this protein?
Dynein axonemal light chain 1, DNAL1, Flagellar outer arm dynein light chain 1, ODA-LC protein LC1.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain LC1-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: ETAA1_MOUSE
Sequence: MQLKDGGTGMSRRRKHADSPARRSTPHRAAAKNCRPAAEPWLRESRAACSSQLRRAGTRSARRAQRQAAADGGRSPRGKETPVQIVKMDLLSCTFSSPNDPDGQTDIFWDQNSPMTKQLGKGRKKQISSAYSDEISHIVNRIAPQDEKPVTNSMLGVWIGETAIPCTPGVAKEKSRVKASCTKLKTKNREKELMKLAQQFDKNMEELDVIQEQDGKNHDFIQMTSKMGHLDNHKDSVQKPSGDVVPEITCTPVKKQMKGDSRISLAKAQDSSQKPFDQNVEAAFNAIFDGSTQMCSGQLSQDLLDAFLNNSKTSLRKKNALLQEEIITTETLLTENLLNKTPISLSPQIDTTVILNSCVTPCPKTPAAPDTQLDELTANDFEDDWESLLGSEPFLMENAEMLEFVPSTTAQDTCQKAICTSVGENDTITSRTNMNLGGRLRDSKVTLDLPSKTRNGELRNAGEHRFSSHPGDESRKVPFTGNKVSFEKSVTSIVSKDEDYVAVSNLEKVKEDSRNKCILNKHSSNKSSSYTRYPSKQSSELGVNLPLQVPTTDPFDSVFLGKENIVCSTNQSHGSKLNSSFDDWNDPLLASEMVEACHRLEATWDAGEVDDDLFCQACDDIERLTQQENKGSEESESVSYTSTRGSRSSSTASKQASQSAPSKHWNVVSSAVPLSLANKSQMSKPVTVQKRGRCGDGPNILDATNLSVCSKNSSDNKRGPVQVNSSKFVLGGSSNLNVNLGLMSTKIATNMKLSTQQLSHNSLADTAQNDNKILKLPKFTFKKKNPQLNQNHLVGSVPVGKISEDLGKRETVNSLLEANQQQSSINYSESLKPSSPDEEERNRKYSPEEIQRKRQEALVRRKAKALHTVQSAPISLP
What is the function of this protein?
Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity.  Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1.  Probably only regulates a subset of ATR targets.
What are the official names of this protein?
Ewing's tumor-associated antigen 1 homolog.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage following replication stress. Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex.
Protein: TATB_SHEPW
Sequence: MFDGIGFMELLLIGVLGLVVLGPERLPVAVRSISGWIRAMKKMANSVKDELEQELKIEQLHTDLKKAENQGLKNLAPELQDSIDQLKQAAESVNRPYQVEDAPSAKETPAKETATTETTSTENAKSDKPNG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLCD_ECOL6
Sequence: MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPYECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGVLLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLGVTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAEDFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFWAGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNMHPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEITTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF
What is the function of this protein?
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.  Is required for E. coli to grow on glycolate as a sole source of carbon.  Is also able to oxidize D-lactate ((R)-lactate) with a similar rate.  Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown.
What are the official names of this protein?
Glycolate oxidase subunit GlcD, Glycolate dehydrogenase subunit GlcD.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Glycolate oxidoreductase activity was shown to be firmly associated with the cytoplasmic membranes.
Protein: COX3_ORNAN
Sequence: MTHQTHAYHMVNPSPWPLTGAMSALLLTSGLIMWFHFNSYTLLLLGLLTNLISSYQWWRDIVREGTYQGHHTKIVQKGLRYGMILFIISEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGISPLNPLEVPLLNTSILLASGVSITWAHHSLMEGNRKQMLQALTITIALGLYFTALQAMEYYEASFTISDGVYGSTFFVATGFHGLHVIIGTTFLITCLVRQTLYHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1166_GEOKA
Sequence: MMMKFINIGYGNMVSAARIITIVSPDSAPIKRIIQDARESGKLVDATHGRRTRAVIIMDSDHVILSSVQPETVANRLYGSDDFSEEG
What are the official names of this protein?
Putative regulatory protein GK1166.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: Y1099_STRP8
Sequence: MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFINDMPEGTYYPQGEMKQKS
What are the official names of this protein?
Probable tautomerase spyM18_1099.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: GACFF_DICDI
Sequence: MNGSPYSSSSWVKSSLSTNSLGSLSNSYAAGSAGGSGNRSTVRGDSNKDQKLLGYLQKQSKSQLPNSNVKIFKKKWFWFESDSGTLFYSATSTGALSTPLTPSSLSENIKSIKITSQTTIEQSISFRLELIIKDKVPNDEFTVLNWVNTLNQWKKLNCNLDFTNDTTTTTNNSNNSNSNNNNKQYNSIENPDYLGKFGEVEGLLNAMSVSTSLNTMKTVKPLINKIQNDSEQLKLVLSQVEQQIEFLKSCQLELISHLSNDNNNNNNNNNNNNNILQILQQQQPISSKRTVSNDNLVGSNNSNNQLSLSIGLPINLNTSNTTTTTITNNTIEGENDDDEEEDEINQTSDIFSLLPTHLTLYVFSYLEPKELLILAQVSSQWQKLAGDNLLWVRFVTHFITPASIFDKSHNWKSVYLANTVTSLGYCSNYYYLKNQQKGGICTNKEKYMNRAISMYGVTPLTSLSSSKEGWLYKRGDDLLRIWKKRYFVLRDSSLFYFKHQNDNFPCGVILLNHGTKLKRASASTRKNCFKILQSKNSTITMVHKKRMPYYLSTDKEDDCNDWMILLNSIIKSNTQHQNNYGVITISGTSNNNNNNVYINNNNNNNNNNNNNNNNNNNNNNNNGSQSYNLPPLLSKSPSFSNALTSSTGISGGGGGSTKSRKSHKKSFSSGGGGSGGNNNFEQMQQQIQSVHLTPIYPMFGVALSKILENQSLITTQTHLKIPFILYICLNYIISKGIKEEGIFRVSGSLREVQELQEHFEQGREIDLDQHDIHAICGLVKTFFRKLPHTLVAADLDEYSTSVQLAASQTEDEKIQEFKFIFESISENSFHIFELLLYCLRLIVRNESFNKMTIENLLIVIMPTLKCSPVLITNGIKYYDEIFIKK
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacFF, GTPase activating factor for raC protein FF.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_SYNSC
Sequence: MLNTPFELVTSLGFAGFVLLLLAMPLAFWAVSSQSRAGLVRLLVAVANLLFTAQLILRWWQSGHFPISNLYESLCFLAWACTLTQLLVERAWPSPIVAAAATPMGLGCIAFASFALPDQLQSAAPLVPALRSSWLVMHVSVIMVSYAALLVGSLLSLAVLVTDRDQSLELRSSSIGSGGFRQAASIANGGSVQLQSVQLSTNEQLDSLSYRTITVGFLMLTVGIVSGAVWANEAWGSYWSWDPKETWALICWLVYAAYLHTRLSRGWQGRRPALVAVVGLVVIAVCYIGVNLLGIGLHSYGWFF
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.