PharMolix/UniProtQA huggingface dataset:
Protein: NADK_METPE
Sequence: MKLLLMSRIDSEETLAYTRTLGIDLENVGFQIIYDTATASALEVNGVPLSSADPDAVVAIGGDGTILLCIQQMNIQRPIIGINRGEVGFLADLEPEEAFSFLKELKPGFPVERRMRIDLSVDGKPLGTALNEAVIVTSRPAKMLRFSVLVDGVRAEQFRGDGLLISTPTGSTAYAMSAGGPIIDPRIEGFLLVPLAPYMLSSRPHLICATRTLAVRLEASKPAHLVLDGQRTIDLGDQATIEMTRSPEPAQFIDVNRNFFSKVEQKLRNL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFBV_ECOSE
Sequence: MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TUPA_PEPAC
Sequence: MKRLLSIITAVMMLALALTGCAAKQSPEGEVEKTQAKGSIILATTTSTSDSGLLDYLLPEFTKDTGIEAKVVAVGTGQALQMGKDGEADVLLVHSKAAEEEFVAAGDGLERKDVMYNDFILVGPANDPLKLKQELPNDIVGALKKISEQKFKFISRGDDSGTHKKELALWTEVGITPEGDYYVSAGRGMGDVLKMADEMQAYTIADRGTYLSMKADLGLDIIVEKDTNLFNQYGVIPVNPDKNENINAEGAKAFEEWILSEKAQSLIGEYGKEKYGAPLFTPNAAK
What is the function of this protein?
Part of an ABC transporter complex involved in tungstate uptake.  Specifically binds tungstate.
What are the official names of this protein?
Tungstate-binding protein TupA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACCA_CHLTB
Sequence: MELLPHEKQVVEYEKTIAEFKEKNKENSLLSSSEIQKLDKRLDRLKEKIYSDLTPWERVQICRHPSRPRTVNYIEGMCEEFVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTKSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPGAFPGLTAEERGQGWAIATNLFELARLATPIIVIVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNSDAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPAATYRSVQEYVLQEWVKLKDLPVEELLEKRYQKFRTIGLYETSSESDSEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_STRMK
Sequence: MSTHNEYDYIIIGAGSAGNVLATRLTEDADVSVLLLEAGGPDYRLDFRTQMPAALAFPLQGKRYNWAYKTDPEPFMNNRRMDCGRGKGLGGSSLINGMCYIRGNAMDYDNWASMPGLEDWTYLDCLPYFRKAETRDIGPNDYHGGDGPLRVTTPKAGNNELFAAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRSSTARGYLDLAKPRPNLTIVTHALTDRILFSGKRAVGVQWLRNDQPQRATARREVLLCGGAIASPQILQRSGVGPADLLRSLDIDLVHHLPGVGANLQDHLEMYLQYECKKPVSLAPALKLYNQPAIGAEWLFLGTGIGASNQFEAGGFIRSDAEFDWPNLQYHFLPVAINYNGSNPIKAHSFQMHVGSMRSPSRGRIHVRSKDPREHPSILFNYMSHEQDWREFRAAIRITREIFAQPALAPYSGREISPGSALQTDAQIDAFVREHAETAYHPSCSNKMGHADDPMAVVDGQGRVHGLEGLRIVDASIMPQVVTGNLNAPTIMMAEKLADVIRGRTPLARSTAPYYKANGAPVRKQD
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: ACP_CERSK
Sequence: MSDIADRVKKIVVEHLGVEEEKVTENASFIDDLGADSLDTVELVMAFEEEFGIEIPDDAAETIQTFGDAVKFISEAA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP2_AJECN
Sequence: MSYGGGYGSSRDHYGGGGGGGYSRGGGYGNGYGNSNGYSHGHSSGGYGSYGGAGGYGGGTGGDRMSNLGAGLKTQNWDLSTMPKFEKSFYKEHPNVSQRSTHEVDAFRKEHEITVQGKNVPRPVETFDEAGFPQYVMSEVKAQGFARPTAIQAQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTEITKFGKSSRIRNTCVYGGVPKGPQIRDLTRGVEVCIATPGRLIDMLEAGKTNLRRVTYLVLDEADRMLDMGFEPQIRKIVSQIRPDRQTCMWSATWPKDVRQLAQDFLHDYIQVNIGSMDLSANHRITQIVEIVSEFEKRDRMAKHLDRIMEANKHSKVLIFTGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLNEFKTGKSPIMVATDVASRGIDVRDITHVLNYDYPNNSEDYVHRIGRTGRAGAKGTAITLFTTDNAKQARDLVAILSESKQQIDPRLAEMARYGSGGGGNRWGGRGRGRGGFTASNAAPLGNNRRW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
ATP-dependent RNA helicase DBP2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNME_CHLL3
Sequence: MPASVVLQQPDIPIAAIATPVGVGALAIVRMSGKGVFGIADRAFRKKSGKAFSFEAAEGFTAHVGTLFDGEGMVDEVVALVFRAPSSFTMEDMVEFTCHGGPVVVRRVLAALLDGGCRLAEPGEFTRRAFLNGRIDLLQAEAIGEMIHARTDGAFRTAVTQMQGGLSRRLLEMREGLLQSCALLELELDFSEEDVEFQSREELRGEVIRLQTELSGLVDSYQHGRLLSEGVSTVIAGRPNAGKSTLLNKLLGEERSIVSHMPGTTRDYIEECFVYDKTMFRLTDTAGLRESEEDVEHEGIERSYRKISEADLILYMLDVSGEGFREEAVSAAALCAGHPEARMILLANKTDLVKDSALRIAALETAAGSPVVPMAARSGEGIEELKLLMASMVEGLDKLHEASVLVTSLRHYEALRNASDALHNALGLIEGGEATELIAFELRSALDYVGEITGKVVSEELLNTIFGQFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECF_HELPJ
Sequence: MELFKQVRILSFMRYSNYGVIVSAILVLLALGLLFFKGFSLGIDFAGGSLVQVRYTQNAPIKEVRDLFEKEARFKGVQVSEFGSKEEILIKFPFVETAENEDLNAIVANILKPSGDFEIRKFDTVGPRVGSELKEKGILSLILALIAIMVYVSFRYEWRFALASVVALVHDVILVASSVIVFKIDMNLEVIAALLTLIGYSINDTIIIFDRIREEMLSQKTKNATQAIDEAISSTLTRTLLTSLTVFFVVLILCVFGSKIIIGFSLPMLIGTIVGTYSSIFIAPKVALLLGFDMGKYYENEARKIKKAQEKEKMRRLYEGGQV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRIO_CHLAE
Sequence: MANLGCWMLVVFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: CED7_CAEEL
Sequence: MNRLRQFSLLLWKDWVLLRRNKVWTLFELIIPCLLLGPLVYLVVKNADHTSSPENIYDNFQVKGTVEDVFLESNFIKPIYKRWCLRSDVVVGYTSKDAAAKRTVDDLMKKFAERFQSAKLKLSVKNESSEEQLLTVLRNDLPMLNETFCAINSYAAGVVFDEVDVTNKKLNYRILLGKTPEETWHLTETSYNPYGPSSGRYSRIPSSPPYWTSAFLTFQHAIESSFLSSVQSGAPDLPITLRGLPEPRYKTSSVSAFIDFFPFIWAFVTFINVIHITREIAAENHAVKPYLTAMGLSTFMFYAAHVVMAFLKFFVIFLCSIIPLTFVMEFVSPAALIVTVLMYGLGAVIFGAFVASFFNNTNSAIKAILVAWGAMIGISYKLRPELDQISSCFLYGLNINGAFALAVEAISDYMRRERELNLTNMFNDSSLHFSLGWALVMMIVDILWMSIGALVVDHIRTSADFSLRTLFDFEAPEDDENQTDGVTAQNTRINEQVRNRVRRSDMEIQMNPMASTSLNPPNADSDSLLEGSTEADGARDTARADIIVRNLVKIWSTTGERAVDGLSLRAVRGQCSILLGHNGAGKSTTFSSIAGIIRPTNGRITICGYDVGNEPGETRRHIGMCPQYNPLYDQLTVSEHLKLVYGLKGAREKDFKQDMKRLLSDVKLDFKENEKAVNLSGGMKRKLCVCMALIGDSEVVLLDEPTAGMDPGARQDVQKLVEREKANRTILLTTHYMDEAERLGDWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRNASEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEKSGVAKMVAQFISIMRKKFLYSRRNWAQLFTQVLIPIILLGLVGSLTTLKSNNTDQFSVRSLTPSGIEPSKVVWRFENGTIPEEAANFEKILRKSGGFEVLNYNTKNPLPNITKSLIGEMPPATIGMTMNSDNLEALFNMRYYHVLPTLISMINRARLTGTVDAEISSGVFLYSKSTSNSNLLPSQLIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWMYDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLKSILVNIFMFLLPSYAFGSAIITINTYGMILPSEELMNWDHCGKNAWLMGTFGVCSFALFVLLQFKFVRRFLSQVWTVRRSSHNNVQPMMGDLPVCESVSEERERVHRVNSQNSALVIKDLTKTFGRFTAVNELCLAVDQKECFGLLGVNGAGKTTTFNILTGQSFASSGEAMIGGRDVTELISIGYCPQFDALMLDLTGRESLEILAQMHGFENYKAKAELILECVGMIAHADKLVRFYSGGQKRKISVGVALLAPTQMIILDEPTAGIDPKARREVWELLLWCREHSNSALMLTSHSMDECEALCSRIAVLNRGSLIAIGSSQELKSLYGNNYTMTLSLYEPNQRDMVVQLVQTRLPNSVLKTTSTNKTLNLKWQIPKEKEDCWSAKFEMVQALAKDLGVKDFILAQSSLEETFLRLAGLDEDQLDTHSTVEISHSTHV
What is the function of this protein?
Functions in the engulfment of cell corpses during embryonic programmed cell death to translocate molecules that mediate homotypic adhesion between cell surfaces of the dying and engulfing cells.
What are the official names of this protein?
ABC transporter ced-7, Cell death protein 7.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TAF4_ARATH
Sequence: MDLSIVKLLEEDEEVDSKHSEDDLQMFQDSLIRDIEGSNLKSINNTTGNESEKPQPRYMKLQKMSSKETPWVEKTVDPVNHNLRLARVTDLLRTVVDHQPGKKTHCLNLHYKLKRKELTMEEFMRQLRDLVGDQIIRSVISQLPQLKPGNMGIKVPGRSNHDKVSKSAEFTAQESDPREVHVNQLSSTTSGTLNSSTTVQGLNKHPEQHMQLPSSSFHMDTKSGSLNPYPGTNVTSPGSSSRAKLPDFQHRENNQNVGIASVGGPTKSTINMTTVPKFERPTFVNGPSRVQDGPISDFPKNSSFPLYSAPWQGSVTKDHTVGPSSSVIHVEHKLIDQSFEQAHKPRYLVQQGVTNVPLKQKNAIPISSNDDLEKQSSKMGLFTSTTSASSVFPSMTTQLDSSTMVNMPAPSETIPKIANVTVTPKMPSVGQKKPLEALGSSLPPSRKKQKICGTSSDESIEKFNDVTAVSGINLREEEKQLLDSGPKKNDRVSKAYRRLVHGEEERTLLQKIPLQRKLTEIMGKSGLKHIDHDVERCLSLCVEERMRGLLFNIIRISKQRTDAEKCRNRTFITSDIRKEINEMNQKVKEEWEKKHSGEEKNKENDTEKEDQRSNEVKANKKDEDKERAKAANVAVRAAVGGDDRFSKWKLMAEARQRSSPGPGRNSKKLSGGTQFGKNQGLPKVVRSISVKDVIAVVEKEPQMSRSTLLYRVYNRICSDV
What is the function of this protein?
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 4, TBP-associated factor 4, AtTAF4.
What is the protein family that this protein belongs to?
Belongs to the TAF4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TINA1_DROME
Sequence: MGQAKKVSSALSKLFVYGALKYGQPSNSILASSGNGFAKFWCKATTTQKLPLVIATRYNIPFLLNKPGVGYYVTGEIYEVDDRMLNSLDNLEDCEEIYTREMHDMNIGVGEGTVPCWVYLLQKYPENLLSLRYLSSYENSTTHPYIMRHRRTHKHPAQDDLTYEAQN
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
Troponin C-akin-1 protein, Putative gamma-glutamylcyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: CR1AB_BACTK
Sequence: MDNNPNINECIPYNCLSNPEVEVLGGERIETGYTPIDISLSLTQFLLSEFVPGAGFVLGLVDIIWGIFGPSQWDAFLVQIEQLINQRIEEFARNQAISRLEGLSNLYQIYAESFREWEADPTNPALREEMRIQFNDMNSALTTAIPLFAVQNYQVPLLSVYVQAANLHLSVLRDVSVFGQRWGFDAATINSRYNDLTRLIGNYTDHAVRWYNTGLERVWGPDSRDWIRYNQFRRELTLTVLDIVSLFPNYDSRTYPIRTVSQLTREIYTNPVLENFDGSFRGSAQGIEGSIRSPHLMDILNSITIYTDAHRGEYYWSGHQIMASPVGFSGPEFTFPLYGTMGNAAPQQRIVAQLGQGVYRTLSSTLYRRPFNIGINNQQLSVLDGTEFAYGTSSNLPSAVYRKSGTVDSLDEIPPQNNNVPPRQGFSHRLSHVSMFRSGFSNSSVSIIRAPMFSWIHRSAEFNNIIPSSQITQIPLTKSTNLGSGTSVVKGPGFTGGDILRRTSPGQISTLRVNITAPLSQRYRVRIRYASTTNLQFHTSIDGRPINQGNFSATMSSGSNLQSGSFRTVGFTTPFNFSNGSSVFTLSAHVFNSGNEVYIDRIEFVPAEVTFEAEYDLERAQKAVNELFTSSNQIGLKTDVTDYHIDQVSNLVECLSDEFCLDEKKELSEKVKHAKRLSDERNLLQDPNFRGINRQLDRGWRGSTDITIQGGDDVFKENYVTLLGTFDECYPTYLYQKIDESKLKAYTRYQLRGYIEDSQDLEIYLIRYNAKHETVNVPGTGSLWPLSAPSPIGKCAHHSHHFSLDIDVGCTDLNEDLGVWVIFKIKTQDGHARLGNLEFLEEKPLVGEALARVKRAEKKWRDKREKLEWETNIVYKEAKESVDALFVNSQYDRLQADTNIAMIHAADKRVHSIREAYLPELSVIPGVNAAIFEELEGRIFTAFSLYDARNVIKNGDFNNGLSCWNVKGHVDVEEQNNHRSVLVVPEWEAEVSQEVRVCPGRGYILRVTAYKEGYGEGCVTIHEIENNTDELKFSNCVEEEVYPNNTVTCNDYTATQEEYEGTYTSRNRGYDGAYESNSSVPADYASAYEEKAYTDGRRDNPCESNRGYGDYTPLPAGYVTKELEYFPETDKVWIEIGETEGTFIVDSVELLLMEE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae.
What are the official names of this protein?
Pesticidal crystal protein Cry1Ab, 130 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIA(b).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: SECA_CLAM3
Sequence: MASVLEKVLRVGEGRTLRKLQNYAKAVNQLEEDFTHLTDEELKNETVELRERHANGESLDDLLPEAFAAVREASRRTLGLRHFDVQIMGGAALHLGNIAEMKTGEGKTLVATLPAYLNAIASRGVHVITVNDYLASYQSELMGRVFRALGMTTGVILAGQTPQQRREQYAADITYGTNNEFGFDYLRDNMAWQASDMVQRGHFFAVVDEVDSILIDEARTPLIISGPSAGDANRWFTEFATVAKRLVPEVDYEVDEKKRTVGVLEAGIEKVEDHLGIDNLYESANTPLISFLNNSIKAKALFKKDKDYVVMNGEVLIVDEHTGRILMGRRYNEGIHQAIEAKEGVAVKAENQTLATVTLQNYFRLYKKLSGMTGTAETEAAEFMSTYKLGVVPIPTNRPMQRKDQSDLIYKNEKAKFEQVVEDIAERHAAGQPVLVGTTSVEKSEYLSKLLAKKGVRHEVLNAKNHAREAAIVAQAGRLGSVTVATNMAGRGTDIMLGGNAEFLAVAAMNARGLSPVETPEQYETEWDDVFADVKAEVDEEAAKVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLTDDLMRLFNNGAAASLMGRDSVPDDVAIESKVVSRAIRSAQGQVEARNAEIRKNVLKYDDVLNRQREAIYGDRRHILEGDDLQERSQRFLEAVIDDVLDSHIGEGNGDDWDFDALWTELKTLYPISITIDEVITEAGSKGRVNRDFVRREILSDAKLAYSKREEQLGGAAMRELERRVVLSVIDRRWREHLYEMDYLKDGIGLRAMAQRDPLVEYQREGFALFQQMMGAIREETVGFLFNLEVEVQAPADAESVGPRIQAKGLAANQATADKLRYTAPTDDGGVEVRNQRGQIEKAATAKAQKDQQAEDAVLVGEDEPETPQGPPARGAFGQPTGASSSAPQNREERRKADRRK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: DNAK1_STRAW
Sequence: MARAVGIDLGTTNSVVSVLEGGEPTVITNAEGARTTPSVVAFAKNGEVLVGEVAKRQAVTNVDRTVRSVKRHMGTDWKINLDGKDFNPQQMSAFILQKLKRDAEAYLGEKVTDAVITVPAYFNDSERQATKEAGEIAGLNVLRIVNEPTAAALAYGLDKDDQTILVFDLGGGTFDVSLLEIGDGVVEVKATNGDNHLGGDDWDQRVVDYLVQQFKAGHGVDLAKDKMALQRLREAAEKAKIELSSSTETSINLPYITASAEGPLHLDEKLTRAQFQQLTADLLERCKTPFHNVIKDAGINLSEIDHVVLVGGSTRMPAVAELVKELTGGQDANKGVNPDEVVAIGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGIMTKLIERNTTIPTKRSEIFTTAEDNQPSVQIQVYQGEREIAAYNKKLGMFELTGLPPAPRGVPQIEVAFDIDANGIMHVTAKDLGTGKEQKMTVTGGSSLPKDEVDRMRQEAEQYADEDHRRREAAETRNQGEQLVYQTEKFLKDNEDKVPGEVKTEVEASIEELKAALKGESAEGDNTAEIRTATEKVAAVSQKLGQAMYADAQAAQAAGGAEGAAGGEHAKAADDDVVDAEIVDEDRKDGAA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK1, HSP70-1, Heat shock 70 kDa protein 1, Heat shock protein 70-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: KGUA_WOLTR
Sequence: MAVENEGVLLVLSSPSGAGKTTILERLLERSTNLVRSVSMTTRKPRPGEINGKDYFFVTKKEFHELCEAGQMLEYARVFENFYGIPKSFIEQNLSSGISVLLSIDWQGAFHLFELMREKVISVFILPPSMEELRLRLQKRNSDSASEIEHRLAEAQKEMSKRDKYDYVVINDDIDKSVEEISSILDKERLKRSGV
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_PSEPK
Sequence: MHALQAKILDPRLGSEFPLPAYATPGSAGLDLRALLKEDTILEPGQTVLIPTGLSIYIGDPGLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSCWNRGNTPFTIAVGERIAQLVLVPVVQAHFEIVEAFDESQRGAGGFGHSGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: UREF_PSEMY
Sequence: MKPAWALLRLASPQLPIGGYSYSQGLEWAIDSGLIQDADAAERWLADQLTLNLARFEAPLLLAHCRAAHEGNWPHLQELAERHRASRETRELALESRQMGYSLRQLLEGLPELDEAARELLASHHEPGLALAWALAARAWQITPDDALAAWLWGWLENQLAVLMKVLPLGQQAAQRLTSRLLPTLEAAQQQAASLSPEHWGSAAFGLALASMAHERQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_DROSI
Sequence: MENDAGENVDLYVPRKCSASNRIIHAKDHASVQLTIVDVDPETGRQTDGSKTYAICGEIRRMGESDDCIVRLAKKDGIITKNF
What is the function of this protein?
May be an associated component of the ribosome rather than a core structural subunit.  May act as a translation initiation factor.  Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity).
What are the official names of this protein?
40S ribosomal protein S21, Overgrown hematopoietic organs at 23B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: Y1542_HAEIN
Sequence: MDALTLLTTRKSNKKLTAPAPNAEQLERIFEAAMRAPDHGKLHPYHFIVMENESLNKLETLLKAAVVEFDLGEEKLMKAENLAHRAPMVIGVVAKIDPTIAKVPGWEQMLSAGCATYGLQLAAQAQGFDNVWISGKWVNGTALREAFGCREQDRVIALVMIGTGMEKAERECRVIDTKDFVTYL
What are the official names of this protein?
Putative NAD(P)H nitroreductase HI_1542.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: ACCA_BURP1
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLTPWQVSQIARHPQRPYTLDYVSELFTDFHELHGDRAFADDQSIVGGLARFNGHACMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRVAEKFGLPIFTFVDTPGAYPGVGAEERGQSEAIGHNLYVMAELKTPIIATVIGEGGSGGALAIAVADTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIVNEPLGGAHRDPKGMAALLRRALGDSLRQFQGMSVDALRERRFERLMAYGKFKETTPRA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDLI1_MOUSE
Sequence: MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE
What is the function of this protein?
Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (By similarity).  Involved in assembly, disassembly and directioning of stress fibers in fibroblasts.  Required for the localization of ACTN1 and PALLD to stress fibers.  Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 1, C-terminal LIM domain protein 1, Elfin, LIM domain protein CLP-36.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Note=Associates with the actin stress fibers (PubMed:11596114).
Protein: SPRE_RAT
Sequence: MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVEEPSVRVLSYAPGPLDTNMQQLARETSMDPELRSRLQKLNSEGELVDCGTSAQKLLSLLQRDTFQSGAHVDFYDI
What is the function of this protein?
Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
What are the official names of this protein?
Sepiapterin reductase, SPR.
What is the protein family that this protein belongs to?
Belongs to the sepiapterin reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_DEHMC
Sequence: MNLYEVLRRPLISEKNSVHATQNKYAFEIAKGANKRMVKLAVEQAFNVTVEDVNMLHIPGKQKRMGRNLIQTAGLRKAIITLKEGDKITLFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: O3610_CONPE
Sequence: MSGLGIMVLTLLLLVFMETSHQDAGEKQAMQRDAINVRRRRSITRRVSEACEESCEDEEKHCCHENNGVYTCLRYCWG
What are the official names of this protein?
Conotoxin PnMSGL-01.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.