PharMolix/UniProtQA huggingface dataset:
Protein: DXS_SHEDO
Sequence: MSFDISKFPVLAKANTPEDLRKLPQNMLSQVSTELRQFLLQSVGNSSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKIMTGRRDEMHTIRQKNGLHPFPWREESEYDTFSVGHSGTSVSAALGMAIAADKEAAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHKDMLVVLNDNEMSISENVGALNNHLAQLMSGRLYTTIREGSKKVLQGMPVIKEMAKRTEEHLKGMVVPGTLFEELGFNYIGPIDGHDVDALVETMRNMRSLKGPQILHIMTKKGRGYEPAEKDPIGWHAVPKFDPDQFKKPATKPGLPTFSQVFGKWLCDVAAQDDKLLAITPAMREGSGMVEFSQRFPEQYFDAAIAEQHAVTLAAGFACEGFKSVVAIYSTFLQRGYDQLIHDVALQRLPVLFAIDRGGIVGADGATHQGAFDLSFMRCIPNLVIMAPADENECRQMLYTGYRYQDGPTAVRYPRGFATGAEQIEQMTALPIGKGRVCRQGKKIAILNFGTTLASALEVAEQLDASVADMRFIKPLDVDLLHTLALEHDVIVTIEENAIMGGAGSGVIEALHKLKICKPVLQIGLPDEFIKHGAPDEIIAELRLDSKGILAQIQEYLSE
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RNAS8_MIOTA
Sequence: MAPARAGCCPLLLLLLGLRVAQIPVSAKPKDMTSSQWFKTQHVQPSPEACYSAMSNISKYIEWCKDLNTFLHEPFSSVATTCQTPNIACKNRHKNCHQSSGPMSLTMCELTSGKYPNCRYKEKHLNAPYIVACDPPQQGDPGYPLVPVHLDKVV
What is the function of this protein?
Has a low ribonuclease activity.
What are the official names of this protein?
Ribonuclease 8, RNase 8.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADEC_BDEBA
Sequence: MSLSNKKTQKIASDLLPARLSQARGDGTLDLLITNVQMLDVITGDIYPTCIAIGGEHIVGVGMEYQTQSARRTWNALGAFVTPGFIDGHLHIESSMMSPFEFEKATLPLGTTTAICDPHEITNVLGGRGFSWFLRSSELMHQNLFVQMSSCVPALPGFETTGSDFPLEEMKSFKDHPSVLGLAEMMNFPGVIHADEEVLAKIEAFDDLNMDGHAPLLRGKALNAYLLAGIQNCHETVTLEEGREKLQKGMGLIIREGSVAKNLRTLAPLVNEFSSPQCLLCTDDRNPFEIAHEGHINYLIKELINKHGVAVHVAYRLATYSAARHFGLKRLGLVAPGKKADLVFLKDLKAVDIQEVMIGGKFVSELKLQDSLQEKLQTSQPPLENTMKRSPLTEKELTVNLLPGVYNVIEIVPHEIITQHLTVAFDGQKFAESDVLYMANIERYGKGLPPALGLVKGMGLKSGALASSVAHDSHNIMVIGTNPADMVLAVNTLIKSGGGFAVADQGEIKALVELPIAGLLSLKSAEEIKDGIADLKTAFRSLGVHLDEPFIQMAFLALPVIPTLKLTDRGLVNVTNFSFIPLQVEA
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: Y341_STRPN
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYASPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMNDLGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKSADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEELGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK
What are the official names of this protein?
UPF0371 protein SP_0341.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: UBP16_ARATH
Sequence: MLLVLDLGISSLVLVVSLVLPLIGLFVRHKWRVAAQRREEIRRLLIHASEEAARAELEASVEFSSVAVSNVFHCPVCYCLATTRCSRCKAVRYCSGKCQIIHWRQGHKDECHPASIVYDSEDESDSDLRLGEENGQNTPEETLLVGPEPVTIPIGESLLSNRARSPEDGNGDIADNKDDLIDKEEAVSVAETSGSSFSGFSSSPRNDSGDEISRCESFSSSESERSESLLDAHVSVEPEDTCFSTIEDAPSKLLSPKFVHLVESVDNLANLPKLSVHKPEDDAGQNQSQSRSLHSLVTDRHPVSADPSLKSSDFWGTALGSAERVSDSCVKSKSGRPGNSSLHFSFGSGSSRDTSAAKVSEQRSSILKEAPRGTGYISDGVNLRERNAKRFDEAEIALPISSSTDALSPLDSSNLSHVTLPKSKSASSENGSMLAPLKVGEVQLLASKASNTKKCADLMKHSPLGAKSVRVLDHQKQNGAVVQHINSLHGRSGLKASVLKVVDQWTRPKSENEMAGRHGHKGLFPYEVFAKLYTYKIEFQPCGLINVGNSCFANVVFQCLMFTPPLTTYFLQQFHSRACTKKEQCFTCGFEKLVVKAKEEKSPLSPNGLLSQLQNIGIFLGNGKEEDAHEFLRFVVDTMQSVCIKASEYDMTKSSKLEDTTLIGLTFGGYLRSKIKCMKCQVKSELREKMMDLTVEIDGDISTLDDALRRFTRTEILDGENKYRCGSCKSYERAKKKLKITEPPNVLTIALKRFQAGKFGKLNKLIRFPETLDLAPYVSGGSEKSHDYKLYGVIVHLDVMNAAFSGHYVCYIRNQNKWYKADDSTVVTSDVERILTKGAYMLFYARCTPTPPRLAVCTKTEASNKKSRVPLPKANEKSTISRSVSTSSPELSSNTPGGGRSGNIQSFYSSFQRLQKILEEDSASDSSSLFDSNSDECSCSTDSTSMDDFADFIFGDHQGRAHGQSETPSPTSSSSSSSPPFTRRSPLSRSSPETYGTSRHQLPLGGER
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.  Involved in salt tolerance by modulating sodium transport activity and repressing cell death at least partially through modulating SHM1 stability and activity (PubMed:23232097).  Involved in cadmium tolerance by interacting with HIPP27 and probably modulating its stability (PubMed:23857362).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, AtUBP16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRMB_DROME
Sequence: MVATGGQAQDQGQNQEPDVLNPTSAVTGLPQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPGIQQGQQVSFADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNIACLRTNAMKYLPNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKGGLLYTMTDVEDLHKWIVTHMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_SYNPW
Sequence: MPLLNTLATPYAEALLQVTDGRSESDDVAAQCKELLAVWDSSTALRDAMTSPVLEPAAKKQALAQLLAEQIKPSLMNLLKVLADRQRLTALDAVLRRYLELYRESRNISLAHVRCAQALSDDQTKALTAKVQSMVGTGSVEIDLTIDASLIGGFVINIGSQVIDASLSGQVRRLGLSLAKAS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: SPO4_SCHPO
Sequence: MLSMLLPFGNSGVYASDVDREDRPEIAKLVQAFPTIEEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRIYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKYSLPEIGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQWQEADAPTENCCVDKLRKLKQEGKYYDYFPFEKTIADPPEGYLLHDPRPTKRADRAGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNGMSNCALLHGQIWSDNIPTLLDQKHNWLDLIASITKNDENLILETSSDYQVALAIDLLDKLLELHPSKRVKAKTALQHEFFNACGVTRSGFEAENPFRSDFPSTVEQ
What is the function of this protein?
Required for the initiation of meiosis II and progression through anaphase II.
What are the official names of this protein?
Cell cycle protein kinase spo4, Sporulation-specific protein 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
Protein: TRUD_HELPS
Sequence: MNLNFMPLLHAYNHASIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVRIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQEKNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTEQVLEQIARFGMPNYFGPQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNALLSKRLEISKIISAFSVKENLEFFKQKNLNINPNTLKALKNQAHPFKILEGDVMRHYPYGKFFDALELEKESERFLKKEAAPTGLLDGKKALYAKNLSLEIEKEFQHNLLSSHAKTLGSRRFFWVFAENVTSQYVKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RUVB_MYCPU
Sequence: MAKKQEIRPKNFSDFVGQNKLKKLLKVMISSAQVQNRPLDHILFYGNPGTGKTSLASIISNSLNSRIKYAQGNLLDKKTDILTLFASVEENDIIFVDEIHAINKNIEELLYSILEDFVVDIVIGVESNSKIMRLNLKPFTFIGATTQINRISKPLRDRFGLIGQISNYQVEDIEKIIKNNSKKLNIQIDEKATNLIALYSQNIPRLAINLLKRTKDFCIYEECQIIDYKLVNKTLKQLGIYENGLNESQVKYLRSLSETFYKKAVSLDLIVGFLSLQKETIISEIEPLLISNNLIVKTPRGRKITQKGISYLERI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PTS3B_PEDPE
Sequence: MNHQEVADRVLNAIGKNNIQAAAHCATRLRLVIKDESKIDQQALDDDADVKGTFETNGQYQIIIGPGDVDKVYDALIVKTGLKEVTPDDIKAVAAAGQNKNPLMDFLKVLSDIFIPIVPALVAGGLLMALNNVLTAEHLFMAKSVVEVYPGLKGIAEMINAMASAPFTFLPILLGFSATKRFGGNPYLGATMGMIMVLPSLVNGYSVATTMAAGKMVYWNVFGLHVAQAGYQGQVLPVLGVAFILATLEKFFHKHIKGAFDFTFTPMFAIVITGFLTFTIVGPVLRTVSDALTNGLVGLYNSTGWIGMGIFGLLYSAIVITGLHQTFPAIETQLLANVAKTGGSFIFPVASMANIGQGAATLAIFFATKSQKQKALTSSAGVSALLGITEPAIFGVNLKMKFPFVFAAIASGIASAFLGLFHVLSVAMGPASVIGFISIASKSIPAFMLSAVISFVVAFIPTFIYAKRTLGDDRDQVKSPAPTSTVINVNDEIISAPVTGASESLKQVNDQVFSAEIMGKGAAIVPSSDQVVAPADGVITVTYDSHHAYGIKTTAGAEILIHLGLDTVNLNGEHFTTNVQKGDTVHQGDLLGTFDIAALKAANYDPTVMLIVTNTANYANVERLKVTNVQAGEQLVALTAPAASSVAATTV
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in sucrose transport.
What are the official names of this protein?
PTS system sucrose-specific EIIBCA component, EIIBCA-Scr, EII-Scr.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABH_PSEAB
Sequence: MPRAAVVCGLGSYLPEAVLSNDMLAAELDTSDAWISSRTGVRQRHIAGDLGSGDLALRAASAALASAGLERVDAVVLATSTGDFCCPATAPRVAARLGLVGALAFDLSAACTGFVYGLASVGSLISAGLADSALLVGVDTFSHTLDPADRSTRALFGDGAGAVVLRAGDAEEEGALLAFDLGSDGHQFDLLMTPAVSRAERSSGQASNYFRMDGKAVFGQAVTQMSDSVRRVLDRVGWQASDLHHLVPHQANTRILAAVADQLDLPVERVVSNIAEVGNTVAASIPLALAHGLRQGILRDGGNMVLTGFGAGLTWGSVALRWPKIVPTMD
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_RALPJ
Sequence: MNVKTVKCPSCGKPVPWVPESRYRPFCSERCKQIDLGAWAAEQYTIPVVEEDDLPDAPGNDTSGKLN
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: UPPP_SHEB2
Sequence: MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLFAVVIYFRHELWTMFNAWIASIFRGQQSEDSKLAWWIILATLPAVFFGFLAKDFIATHLRNAEVIAVTTVVFGLLLWWADKMSRRDLTVYQTGWRKALLIGFAQALALIPGTSRSGATMTAALMLGLSRDAAARFSFLMSVPVSLGAAILVGKDLAKSELPIDYQALILGTLISFVAAYACIHYFLKIISRMGMTPFVIYRLALGAVLCGFIFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TO1C_ATRRO
Sequence: MNTATGVIALLVLATVIGCIEAEDTRADLQGGEAAEKVFRRSPTCIPSGQPCPYNENYCSQSCTFKENENANTVKRCD
What is the function of this protein?
Insecticidal toxin that reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels (Cav) in cockroach DUM neurons.  Also causes a modest block of insect sodium channel currents (Nav).  Induces potent excitatory symptoms, followed by flaccid paralysis leading to death in house crickets (By similarity).
What are the official names of this protein?
Omega-hexatoxin-Ar1c, Omega-HXTX-Ar1c, Omega-atracotoxin-Ar1c, Omega-ACTX-Ar1c.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBU_NEOYE
Sequence: MDSTAFVGAAAPLRVAAAARSTICMAAADDKPVVSRRAALTGAAAAALAAVAGSLPALAETEYANVPFLGGSVIIDINNANVRAYAKYPGMYPTVAGLIATNGPFETVSDLYKIPGLTDLQIATLKKYEDKLVALTPTPEYELDKVNNGLYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation (By similarity).
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, chloroplastic, PS II complex 12 kDa extrinsic protein, Protein PYP2.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: EF1A3_SCHPO
Sequence: MGKEKGHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEATELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYNVTVIDAPGHRDFIKNMITGTSQADCAILIIGGGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDTTGWSQARFEEIVKETSNFIKKVGFNPKTVPFVPVSGFQGDNMIEPTTNMPWYQGWQKETKAGVVKGKTLLEAIDSIEPPARPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMIVTFAPAGVTTEVKSVEMHHESLDAGLPGDNVGFNVKNVSVKDIRRGNVCGDSKNDPPMGCASFTAQVIILNHPGQISAGYSPVLDCHTAHIACKFAELIEKIDRRSGKKIEESPKFVKSGDACIAKMVPSKPMCVEAFTDYAPLGRFAVRDMRQTVAVGVIKAVEKVAPGAAKVTKAAVKAGAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha-B/C, EF-1-alpha-B/C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BACCR
Sequence: MDLTQIQNPSFLKDMSISELEGLSEDIRKFLIEELSQTGGHIAPNLGVVELTIALHKLFDSPQDKFLWDVGHQSYVHKILTGRAKEFGTLRQYQGLCGFPKRCESEHDVWETGHSSTSLSAAMGMALARDLKKTKEYVIPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNVLGRLRTAGKYHWVKDELEYILKKIPAVGGKVAATAEKIKDSLKYLLVSGVFFEELGFTYLGPVDGHDYEKLFETLQYAKKTKGPVLVHVITKKGKGYKPAESDVIGTWHGTGPYKIESGDFVKPKEVAPAWSAVVSETVLKLARADERIVAITPAMPVGSKLEKFQKEFPDRMIDVGIAEQHATTMAAGMATQGMKPFLAIYSTFLQRAYDQVVHDICRQNLNVFIGIDRSGLVGADGETHQGVFDISFLRHLPNMVLMMPKDENEGQHLVYTAMQYEDGPIALRYARGNGLGVHMDEELKAIPIGTWETLKEGTQAAILTFGTTIPMAMEAAERLEKAGVSVKVVNARFIKPMDEAYLHDLLGKNIPILTIEEACLIGGFGTGVVEFASENGYHSALVERMGIPDRFIEHGSVTKLLEEIGLTTDAVVDRIHTMIPSKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: EVI5_DROME
Sequence: MTLTTTTTASSAESQAKMDVKGGALPGEENLPTSEMDLLAKLEAANKLIESDAKSLNSLHSTHSRKNSDTSQISLTSSGNSVAEEDIWTTWATILNDWEGALKRKNPCVSELVRRGIPHHFRAIVWQQLSGASDGDKKQYAEYIKATSACEKVIRRDIARTYPEVEFFKEKDGPGQEALFNVIKAYSLHDREVGYCQGSGFIVGLLLMQMPEEEAFAVLVQIMQQHRMRHMFKPSMSELGLCMYQLENLVQEQIPDMHIHFQQQGFQTTMYASSWFLTLYTTTLNVNLSCRIMDVFLSEGMEFIFKVALALLLTGKDTLLCLDMEAMLKFFQKELPGRVEADVEGFFNLAYSIKLNTKRMKKMEKEYQDLKKKEQEEMAELRRLRRENCLLKQRNELLEAESAELADRLVRGQVSRAEEEETSYAIQTELMQLRRSYLEVSHQLENANEEVRGLSLRLQENNVSIDSNNSRQSSIDELCMKEEALKQRDEMVSCLLEELVKVRQGLAESEDQIRNLKAKVEELEEDKKTLRETTPDNSVAHLQDELIASKLREAEASLSLKDLKQRVQELSSQWQRQLAENQRSESERTTNAVDSTPKKLLTNFFDSSKSSEHTQKLEEELMTTRIREMETLTELKELRLKVMELETQVQVSTNQLRRQDEEHKKLKEELEMAVTREKDMSNKAREQQHRYSDLESRMKDELMNVKIKFTEQSQTVAELKQEISRLETKNSEMLAEGELRANLDDSDKVRDLQDRLADMKAELTALKSRGKFPGAKLRSSSIQSIESTEIDFNDLNMVRRGSTELST
What is the function of this protein?
Functions as a GTPase-activating protein (GAP).  During border cell migration in the ovary, acts as a GAP for Rab11 and is necessary for the maintenance of active receptor tyrosine kinases at the leading edge.
What are the official names of this protein?
Ecotropic viral integration site 5 ortholog.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: APTX_TAKRU
Sequence: MPLCWLISVEGNHKPILLPHLQAVVLGRGPETTIKDKKCSREQVELQAECNKGYVKVKQLGLNPTSIDSLVVGKGSVSKMKPGQQLYIVNQLYPYTVQFKEDLSGSTKRSREAVSETRHNDKEEPCRKSSKQGEVSVSVSQKEAPKMSVRSNVHFSLLSILLSGLLSEGVGKMLQGSVGHWNLGLKASMQDPEMQVYKDDKVVVIKDKYPKARYHWLVLPWQSISSLKALRKEHCDLVKHMQQVAEQMIRQCPDASTPRFRSGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFTTDYFIESQAVIQMLETDGSISIKEGATELLKLPLRCHVCRKEFSNIPALKQHLNSHFPS
What is the function of this protein?
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair.  Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species.  Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined.  Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity).  Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
What are the official names of this protein?
Aprataxin, Forkhead-associated domain histidine triad-like protein, FHA-HIT.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: Y852_CLONN
Sequence: MRKNKVLIGLFFCIALTVIFLKKIVNVIINIKWFREVGYLSVYLKRFTSVISLFILVFLICFVAIKTYCRSIKKNLSKNESFIDVDIESKSKGKKIINALTLIISLFIALNFSLGYWDKILEFMNSSKFNVKDPIFNMDISFFIFKLPLIESIYNSLLSLLILLAVITVIVYMFLNIKDRVTLGHKIDRNFININNFKSGITKFAGKQLAILGALLLLCISVGYLIKAWNLSYSPRGVAFGASYTDTKITLKFYIAISIVSIISSIIVAFSILKSKVKPIISCVILIAVLVISERVVSGAWQMLVVKSNERRLETPFIEYNMKYTKKAFGIANVKEQLYPLTNVLNKKSLENNKETINNIKINSVGQALEFYNQVESKKNYYIFNDIDIDRYKINGKYNQVFIAPREIDYEKLQEKANTWQNKHLTYTHGYGVVMSKVNSVTAEGKPDFVIKDMPLVNTSGVEIKDPRIYYGEKTNEYAIVNTKLNEMDYLKDSGENATKNYDGDSGIKMSFINRILFAINKGDMKFLLSSDITSDSRILMNRNIVNRVKKIAPFLKYDNNPYIVINNGKLYWVIDAYTVSNAYPFSEPIGDINYMRNSVKVIIDAVNGTTNFYIIDKNDPIISTYSKIFPGLFKNESEIKEGFREHFKYPQDYFAIQCKAMERYHVKNSGTFFSGQNVWDVAKTQKDIDGKKSVNEASYLIMKLPGEKNEEMILLQYFNQYQRENMIALFGARMDNSNYGNLVLYKFPTTKSETVNSPILFKQKIKQDTTISKELSLWDAKGSQVQFGDTMIIPIDNSLLYVEPLYLRADSERSIPEMKRVIVAYGDKLILAENIEKALSQLFDYDKKNDAKEEVILNKKESVPDELKDAKELYEKAIEAQKQGNWAEYGENIKRLGDILNKLNHPK
What are the official names of this protein?
UPF0182 protein NT01CX_0852.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_SERP5
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLAEVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSPVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGFLNDVEVAKVVSFEAALVAYADREHAELLNHINQTGNFNDEIEGKLKGILETFKKTQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYY_CLOPE
Sequence: MANVLDTLMERGYIKQFTHEAETRELLEKEKVTFYIGFDPTADSLHVGHFIAMMFMAHMQKAGHRPIALIGGGTATIGDPSGKTDMRKMMTNETIAHNVACIKKQMEKFIDFSDDKAILVNNADWLLNQNYVEFLREVGVHFSVNRMLSAECFKQRLERGLSFLEFNYMLMQGYDFYVLNKKYNCKMELGGDDQWSNMIAGVELVRKKSQESAYAMTCTLLTNSEGQKMGKTVNGALWLDPEKTSPYEFYQYWRNVNDADVEKCLKLLTFIPMDEVRRLSSLEGSQINEAKKVLAFEVTKLVHGEEEATKAQQAAEALFGKGGDMSNVPTYEMGKDKLGAELLDILVEAEIVPSKAEGKRLVKQGGLSLNGEKVADFKKTLEEADFENGEVLIKRGKKNYNKIVLA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_RHORT
Sequence: MRHGMSGRKLNRTSSHRKAMFANMAASLLKHEQIKTTLPKAKDLRPIAEKLITLGKGGTLHDRRQAHAILRDDAVVAKLFAVLGPRYKDRQGGYSRILKAGFRYGDAAPMAVIELVDRDPAAKGLDSGPTAEANDDDSEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.