PharMolix/UniProtQA huggingface dataset:
Protein: FSL5_GIBZE
Sequence: MTNLPSHHTAIVGSEDGSLKVAEQVPLPRLENDMILVRNTAVALNPIDGKMVGNLASVGAVAGMDYVGTVVGIGPKVKTASEIQLGDRVCGAVQGMHSLTPSVGAFAQFVGATDIVTLKVPPSMTVEDAATLGSGVGTIGLALFRSLDVPGYPEAPATERIPVLVYGGSTATGTLAIQLLKLSGLIPITTCSPHNFDLVKSFGAEAVFDYRRPETPDEIRKFTRNSLKYVLDCISEPETMQFCYKCIGRTGGKYTALEPFPQFLHTRPTIQPDWVLGPTLLGKPIGWGPPFERVGDPDVREFAIKWFATAQRLLDQGKLQTHPVKLMEGGFEGILCGLEMLKKKQVSGQKLVYMIPQVA
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of fusarielins F, G and H, decaketide compounds with 5 methylations and a decaline core that act as mycoestrogens as they stimulate growth of MCF-7 breast cancer cells (PubMed:22252016, PubMed:27983606).  The initial compound in the pathway is produced by the reducing polyketide synthase FSL1.  FSL1 lacks an active enoyl reductase (ER) domain and biosynthesis of fusarielins relies on the trans-acting enoyl reductase FSL5, before it is released through hydrolysis catalyzed by the thioesterase FSL2 (PubMed:22252016, PubMed:27983606).  Fusarielins F, G, and H have a C11=C12 cis double bond and is fully reduced between C10 and C11 and between C12 and C13.  FSL3 can be involved in the formation of the C11=C12 cis double bond by moving a hypothetical C10=C11 or C12=C13 trans double bond to form prefusarielin (PubMed:27983606).  Prefusarielin is oxygenated at C15 and C16 by the cytochrome P450 monooxygenase FSL4, resulting in fusarielin F, which subsequently is epoxidized into fusarielin G by the same enzyme (PubMed:27983606).  The final step in the pathway is a reduction of the carboxylic acid moiety to yield fusarielin H via a still undetermined mechanism (PubMed:27983606).
What are the official names of this protein?
Trans-enoyl reductase FSL5, Fusarielin biosynthesis cluster protein 5.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: MSHD_GEOOG
Sequence: MSAAPLVRDVDRLDPAGVAAVLALLRAATAADGVRPLSEEAELRLQHGGPAGGRDVLATAADGALTGYARFEGGEGTGDAEAELVVAPGSRRRGVGRALLTRLEELAGDRPLRVWAHGDLPGSAELAQRHGYERARVLLQMRRELAGVDPEPRLRLPEGVQVRTFRSGTDEQAWLRTNARAFASHPEQGSWTAEDLRLREAEPWFDPAGFFLAWDGDRLLGSHWTKVHPPGDEGPEAVGEVYVLGIDPDAQGLGLGRALTDVGLAHLRRLGLRQVLLYVEEDNTAAVTLYERSGFTRHAVDVSWRRAR
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: RS5_NITEU
Sequence: MTKTTKSANTKTPDEVKTDGLKEKMVSVNRVTKVVKGGRILGFAALTVVGDGKGSVGMGKGKSREVPLAVQKAMDEARQRMVRVNLINGTLHHSVIGRHGAARVYMQPASEGTGIIAGGPMRAIFEVMGVHNILAKCLGSTNPYNIVRATLDGLSKVQTPAMIAAKRGKSIDEITGA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HBA_ODOVI
Sequence: VLSAABKSBVKAAWGKVGGNAAPYGAZALZRMFLSFPTTKTYFPHFBLSHGSAZVKAHGZKVABALTKAVGHLBBLPGTLSBLSBLHAHKLRVBPVBFKLLSHSLLVTLATHLPBBFTPAVHASLBKFLABVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CP121_MYCTU
Sequence: MTATVLLEVPFSARGDRIPDAVAELRTREPIRKVRTITGAEAWLVSSYALCTQVLEDRRFSMKETAAAGAPRLNALTVPPEVVNNMGNIADAGLRKAVMKAITPKAPGLEQFLRDTANSLLDNLITEGAPADLRNDFADPLATALHCKVLGIPQEDGPKLFRSLSIAFMSSADPIPAAKINWDRDIEYMAGILENPNITTGLMGELSRLRKDPAYSHVSDELFATIGVTFFGAGVISTGSFLTTALISLIQRPQLRNLLHEKPELIPAGVEELLRINLSFADGLPRLATADIQVGDVLVRKGELVLVLLEGANFDPEHFPNPGSIELDRPNPTSHLAFGRGQHFCPGSALGRRHAQIGIEALLKKMPGVDLAVPIDQLVWRTRFQRRIPERLPVLW
What is the function of this protein?
Catalyzes C-C bond formation between the carbons ortho to the phenolic hydroxyl of cyclo(L-tyr-L-tyr) (cYY) producing mycocyclosin.  Can also use cyclo(L-Tyr-L-Phe) (cYF), cyclo(L-Tyr-L-Trp) (cYW) and cyclo(L-Tyr-L-3,4-dihydroxyphenylalanine) (cY-DOPA) as substrate.
What are the official names of this protein?
Mycocyclosin synthase, Cytochrome P450 121, Cytochrome P450 MT2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAEHP_METBU
Sequence: MMLIGEALIGEAPELAHVDLMIGDKEGPVGQAFATGMTQLSAGHTPVLSVIRPNLPTKPSTLIVPKVTVKGMDQASQIFGPAQAAVSKAVADAVEEGLIPKEKAEDLVIIASVFIHPQAVDYNRIYRYNYGATKLALKRALDGFPDIDTVLHEKDRAAHAVMGFKISKLWDAPYLQVALDNPNLPVILNIIKQLPKSDHLILEAGTPLIKRYGVDVISKIREVRPDAFIVADLKTLDTGNLEARMVADATADAIVVSALAPIATLNKVIEEAHKTGIYAVMDTLNTPDPVAVLEQLDVLPDVVELHRAIDIEGTAHAWGSIEGIKALAVKRSSKVLVAVAGGVRVDTISDALGAGADILVVGRAITNSKDVRQAADRFIEGLNKPEIDQFRIMTDF
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: TRPR_ENTCL
Sequence: MTQHSPYSSAMAEQRHQEWLRFVELLRQSYDKDLHLPLLQLMLTPDEREALGTRVRIIEELLRGEMSQRELKNELGAGIATITRGSNSLKSAPVELRQWLEQILLGAQR
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_BACSU
Sequence: MKLFKNLTVQVITAVIIGVIVGLVWPDVGKEMKPLGDTFINAVKMVIAPIIFFTIVLGIAKMGDMKKVGKVGGKAFIYFEVVTTLALIIGLFVVNIMKPGAGLDYSKLEKGDVSQYTQNGGQGIDWIEFITHIVPSNMVDAFAKGDILQVLFFSILFGVGLAALGEKGKSVIDFFDKVSHVFFKIIGYIMRAAPIGAFGAMAYTIGHFGLDSIKPLASLMMSVYITMFLFVFVALNIICKLYGFSLWNYLRFIKDELLIVLGTSSSESVLPRMMDKMERYGCSKSVVGLVIPTGYSFNLDGTSIYLSMATVFLAQVFGVDLSIGQQITIILVLMLTSKGAAGVTGSGFIVLASTLSALQVIPLEGLALLLGVDRFMSEGRAIVNLIGNGIATIIVAKSENEFDEAKSIEAVEGMKKMKTAV
What is the function of this protein?
Responsible for the transport of succinate and fumarate, but not malate, across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein, C4-dicarboxylate permease.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDRP_BYDVP
Sequence: MFFEILIGASAKAVKDFISHCYSRLKSIYYSFKRWLMEISGQFKAHDAFVNMCFGHMADIEDFEAELAEEFAEREDEVEEARSLLKLLVAQKSKSGVTEAWTDFFTKSRGGVYAPLSCEPTRQELEVKSEKLERLLEEQHQFEVRAAKKYIKEKGRGFINCWNDLRSRLRLVKDVKDEAKDNARAAAKIGAEMFAPVDVQDLYSFTEVKKVETGLMKEVVKEKNGEEEKHLEPIMEEVRSIKDTAEARDAASTWITETVKLKNATLNADELSLATIARYVENVGDKFKLDIASKTYLKQVASMSVPIPTNKDIKLKMVLQSPEARARRERMDVLDSVGFLEGLCTASGFESPFPILGLPEIAVTDGARLRKVSSNIRYLSQTHLGLVYKAPNASLHNALVAVERRVFTVGKGDKAIYPPRPEHDIFTDTMDYFQKSIIEEVGYCKTYPAQLLANSYSAGKRAMYHKAIASLKTVPYHQKDANVQAFLKKEKHWMTKDIAPRLICPRSKRYNIILGTRLKFNEKKIMHAIDSVFGSPTVLSGYDNFKQGRIIAKKWQKFACPVAIGVDASRFDQHVSEQALKWEHGIYNGIFGDSEMALALEHQITNNIKMFVEDKMLRFKVRGHRMSGDINTSMGNKLIMCGMMHAYLKKLGVEAELCNNGDDCVIITDRANEKLFDGMYDHFLQYGFNMVTEKPVYELEQLEFCQSKPVSINGKYRMVRRPDSIGKDSTTLLSMLNQSDVKSYMSAVAQCGLVLNAGVPILESFYKCLYRSSGYKKVSEEFIKNVISYGTDERLQGRRTYNETPITNHSRMSYWESFGVDPKIQQIVERYYDGLTVSAQLQSVKVTTPHLQSILLSIPENHSQNEY
What is the function of this protein?
Probable polymerase.
What are the official names of this protein?
Putative RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the luteoviruses RNA polymerase family.
Protein: RL34_POLNA
Sequence: MKRTYQPSKVKRARTHGFLTRMKTRGGRAVIAARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ATG22_YARLI
Sequence: MDIVATTQKELYGWYAYAWAAEPFMVVAVATYIPQLLQSYARQNAVLADDHSQPCDSPPVPFPGDPGVPTDPGIPPNNSLSSSVPWFLRANEIQLLESPDTVHTMKDHKAKPTQPTCVIKFFGIYIDTASFPLYTFSLSVLLQVVVVISMSGAADRGRFRKQLLLFFGIAGALTTGLFVFITPKRYYLGSFLAIVSNAAFGAATVCGNAYLPVLAAGMKDGTTSEEPSEPSTPSDTSKPASRSENTPLLSASGVDYETGESSNTAEIVKIDHRANVSARISGTGVALGYLAGFIVQIISIYLVITTGSTTWSLRLALLIVGVWWLIFQIPVLMWLKPRPGPPLPIKTDPQNHPWTATLDRVTNGGWSYVTYGWKTLLVTFKEARQMKDVALFLVGWFLVSDGITTINSTAVLFAQGELRMSPANLAVMGMLVVISGISGAKLTPLIGGTRASPIKSIVVVVSLAAAVPAYGILGFFFTNIGLKNPWELYVLAVWYGFALGGLNTVCRSTFSMLIPRGKEAVFFSLFSVTDKGSSVLGPLLVGLIVDKTHNLRHAFYLLLVLLITPIGLFLMIDMERGRKEAEYLETVEE
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: PSRP_BURM1
Sequence: MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFVDSLEKAYATVEKINEAAVHDGRRSIVFTTLVDSESNEIVKRSNALVLDMFQRFVEPLEQELQLKSSHAMGRGHQNADTEEYKTRIEAINFSLAHDDGQSNRNLSEADVILVGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPSALAPHRDKLFGLSIDPQRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGIKWLSSTHKSIEEIATTILQEIRLERQSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RL18_FRATW
Sequence: MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIADRCKEKGISQVAFDRSGYKYHGRVKALVEAAREHGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SECA2_STRA3
Sequence: MTAFNSLFSLDKKRLKKLQRTLNTINSLKGQMATLSNEELQAKTTEFRKRLVNGETLDDICAEAFAVVREADKRVLGLFPYDVQVIGGLVLHQGNTAEMKTGEGKTLTATMPLYLNALEGKGAMLLTNNSYLAIRDAEEMGKVYRFLGLSVGVGVSDNEEEDRDAATKRAVYSSDIVYSTSSALGFDYLIDNLASSKSQKYMPKLHYAIVDEADAVLLDMAQTPLVISGSPRVQSNLYKIADELILSFEEQVDYYFDKERQEVWIKNQGVREAERYFRIPHFYKQSNRELVRHLNLSLKAHKLFERGKDYVVDDGEIKLLDATNGRVLEGTKLQGGVHQAIEQKEHLNVTPESRAMASITYQNLFRMFTKLAGMTGTGKTAEKEFIEVYDMEVVRIPTNSPVRRIDYPDKIYTTLPEKIHATIEFVKQVHDTGQPILLVAGSVRMSELFSELLLLSGIPHSLLNAQSAVKEAQMIAEAGQKGAVTVATNMAGRGTDIKLGKGVSELGGLAVIGTERMKSQRMDLQLRGRSGRQGDIGFSQFFVSFEDDLMIESGPKWAQDYFRKNRDKVNPEKPKALGQRRFQKLFQQTQEASDGKGESARSQTIEFDSSVQLQREYVYRERNALINGESGHFSPRQIIDTVISSFIAYLDGEVEKEELIFEVNRFIFDNMSYNLQGISKEMSLEEIKNYLFKIADEILREKHNLLGDSFGDFERTAALKAIDEAWIEEVDYLQQLRTVATARQTAQRNPVFEYHKEAYKSYNIMKKEIREQTFRNLLLSEVSFNENGDLQIYFI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: AP1S2_MOUSE
Sequence: MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes.  The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).
What are the official names of this protein?
AP-1 complex subunit sigma-2, Adaptor protein complex AP-1 subunit sigma-1B, Adaptor-related protein complex 1 subunit sigma-1B, Clathrin assembly protein complex 1 sigma-1B small chain, Golgi adaptor HA1/AP1 adaptin sigma-1B subunit, Sigma 1B subunit of AP-1 clathrin, Sigma-adaptin 1B, Sigma1B-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: FTHS_THEPX
Sequence: MKSDIEIAQEAKMLHIREVAKKLDIEEDYLEYYGKYKAKISPALSEKIKDRKDGKLILVTAITPTPAGEGKTTLTVGLGQALAKIGKKAMIALREPSLGPCMGIKGGAAGGGYSQVVPMEDINLHFTGDLHAITAAHNLLAAMIDNHIHHGNELNIDIRAITWKRAMDMNDRALREIIVGLGGKANGFPRQDGFIITVASEVMAILCLAQDLMDLKRRIGDIIVAYDKDGNPVTARDLKADGAMTVLLKDAIKPNLVQTIENVPAFVHGGPFANIAHGCNSLIATKYGLKLADYLVTEAGFGADLGAEKFFDIKSRFGGLTPNAAVIVATVRALKMHGGVKKEDLQKEDVEAVRRGIENLEKQVENVRKFGVPVVVALNRFVFDTEREIEEVRKACEEMGVDMAVAEVWEKGGEGGIELAEKVVKACETPSNFHVLYDETLPIKDKLHIIATEIYGADGVEYTASALKDIANLERLGFDKMPIVVAKTQYSLSDDPKLLGRPRGFKITVRELRVSMGAGFVVVFTGDIMTMPGLPKHPAAENIDIDENGRITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: KI21A_HUMAN
Sequence: MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN
What is the function of this protein?
Microtubule-binding motor protein probably involved in neuronal axonal transport.  In vitro, has a plus-end directed motor activity.
What are the official names of this protein?
Kinesin-like protein KIF21A, Kinesin-like protein KIF2, Renal carcinoma antigen NY-REN-62.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, axon. Note=In neurons, localized to axons and dendrites.
Protein: PEN7_ARATH
Sequence: MWKLRIGAKAGDDPHLCTTNNYLGRQIWEFDTNACSPEELFEVEKARRNFSDNRSQYKASADLLWRMQFLREKKFKQNIPRVKIEDAEKITYEEANMTLRRGIHYMAALQSDDGHWPAENSGCMFFNAPFVICLYITGHLDTIFSQEHRKEMLRYIPIIKNDDGGWGLDVESHSSMFCTVLNYICLRIMEVDPDHDRKKSACARARKWIIDRGGATYTPLFGKACLSVLGVYEWSGCKPIPPEFWLFPSYFPINGGTVWIYFRDTFMALSYLYGKKFVATPTPLILQLRQELYPQTYADIVWSQARNRCAKEDLYYPQTFVQDLFWKSVHMFSENILNRWPFKKLIRERAIRRALELIHYHDEATQYITGGGVPKVFHMLACWAEGPESGYFKKHLARVSGFIWISEDGLKIQSFGSQIWDTVLLLKVMLAADIDDEIRSMLIKGYSFLRKSQLIENPPGYYIKMFRDISKGGWGFSDKDQGWPASDCTSESLECCLIFESMPSNFIDEKMDVERLYDAVNMLLYLQSENGGKAVWERASGKKWLEWLSPIEFMEETILEHEYVECTGSAVVVLTRFMKQFPRHRTKEIETFIAKAVKYIESLQMADGSWYGNWGVCFIYATFFAVRGLVAAGKTYQSYEPIRRAVQFLLKIQNDEGGWGESFLSCPGKKYISLEGNKTNVVNTGQAMMVLIMSGQMERDPLPVHRAAKVLINSQMENGDFPQQELRGVYKMNVLLHYPTYRNIFSLWALTYYTKALRLLL
What are the official names of this protein?
Putative pentacyclic triterpene synthase 7, AtPEN7.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: HIS7_CHLTE
Sequence: MTQRIASHSRKTAETDISATVNLDGSGTSAIETGVVFLDHMLTNFSRHSGIDVQLRCSGDLEVDDHHTVEDVALVLGKAIVDALGDKKGIGRYGWAIIPMDEALAQCSIDLGGRSYCVFRAEFQRPVIQGLSTEMVEHFFVSLSRTMNANLHLAVLEGRNTHHMIEALFKSLAYAMKQAVKVESTEIKSTKGAI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRFC_CHICK
Sequence: MSCFDLCRPCGPTPLANSCNEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAAGSSTSAAVGSILSEEGVPISSGGFGISGLGSRFSGRRCLPC
What are the official names of this protein?
Feather keratin 1, F-ker, Keratin gene C protein.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: RS15_BRUSU
Sequence: MSITAERKQALIKEYATKEGDTGSPEVQVAVLSERIANLTEHFKGHKNDNHSRRGLLKLVSQRRRLLDYVKGVDHARYQALITRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FDX2_DANRE
Sequence: MAAAAAVRAGVNFTQRLNRISPVCRVCPLLRLNRCTGAAVRRAVDGFSAPSRRLRTSIGVCQSEDSSAPEEDAHAQEHIVNVVYIDRSGRRIPVQARVGDNVLYLAHKHGIDLEGACEASLACSTCHVYVSSGHYDRLPEPEEREDDMLDMAPLLQENSRLGCQIILTPELDGMELTLPKVTRNFYVDGHVPKPH
What is the function of this protein?
Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU (By similarity).  The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis.  This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner.  Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly.  Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5 (By similarity).
What are the official names of this protein?
Ferredoxin-2, mitochondrial, Adrenodoxin-like protein, Ferredoxin-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LEU1_HALOH
Sequence: MGEVKIFDTTLRDGEQSPGVSLIPEEKLAIAKQLARMKVDVIEAGFPISSPGDFEAVQIISENIRDVEVAALARSRKKDIDRAWEALRNGGDPRIHVFIATSPIHMKYKLKLSEEQVIEKAVEAVKYASKYTSNIEFSAEDASRSQPVFLYRLFERVINAGAKVINIPDTVGYAIPEEFGKLIRDIKENVSNIDKVDISVHCHNDLGLAVANSLAAVENGANQIEVAVNGIGERAGNTALEEIIMALYTRKDFYNIGINQDTTQIARLSKLVSNLTGMTIQPNKAIVGANAFAHESGIHQDGVIKERTTYEIMDARTIGLKDNKLVLGKHSGRHAFREFIQKLGYDIDDETFEEIFIEFKKLADKKKNITHVEIEALIDNHYHTFDKVYELDYLSVNTGNKVLPTATIKLKKENNIIEKAACSGDGPVDAIFQAINEIVGIDDIKLISYHINAVTEGKDALGEVIVKTKIEDNTYTGHSAMTDITEASALAYLETINKFLTSEQTRQTTSAQEGI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RS3A_EIMTE
Sequence: MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMFSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTGEFQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGGAGKPSGDEAGAKVERADGYEPPVQESV
What are the official names of this protein?
40S ribosomal protein S3a, EtS3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_GEOTN
Sequence: MEQEKRVFSIDVAGRPLVIETGELAKQANGAALVRYGDTVVLSTATASREAKDVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFAEGFRNEVQVVSMVMSVDQDCSPEVAALIGSSVALTISDIPFEGPIAGVIVGRIDGQFVINPTVEQMEKSDMHLIVAGTKDAINMVEAGADEVPEEVMLEAIMFGHEEVKRLIAFQEEIAAQVGKEKMEVVLYEPDPELEAEIRQLAEADIKKAVQVPEKLARDAAIEDVKAGVIAKYEAEEADEEKLKQVQEILHKLVKEEVRRLITVEKIRPDGRKVDEIRPLSSAVGILPRTHGSGLFTRGQTQVLSVCTLGALGDVQILDGLDLEESKRFMHHYNFPPFSVGETGPMRGPGRREIGHGALGERALEPVVPSEREFPYTIRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKNEDHYTILTDIQGIEDHLGDMDFKVAGTRKGVTALQMDIKIKGLTRDILEEALQQARKGRLEILDHMMQTLSEPRKELSKYAPKILIMHINPDKIREVIGPSGKQINKIIDETGVKIDIEQDGTIFISSVDEEANQKAKQIIEDIVREVEVGQVYLGKVKRIEKFGAFVELFNGKDGLVHISELAEERIGKVEDIVSIGDEILVKVTEIDKQGRVNLSRKAVLREQRGAGELPKETREKRGRRPERHRMKP
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_STACT
Sequence: MQHKSPVVTWDLFGLDIKFNLASILMVIITSLIVLVIAIACTRNLQKRPTGKQNFIEWVFDFVRGIIESNLAWKKGGQFHFLTVTLILFIFVGNMLGLPFAIVIDHTLWWKSPTADATVTLTLATMVILLTHYYGIKMRGTKNYFKNYGQPFLALTPVNIFEEFTNTLTLGLRLYGNIYAGEILIGLLSSLIIGHAAWGWIIGVPGLIAWQAFSIFIGTIQAYIFIMLSMVYMSHKIADDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.