PharMolix/UniProtQA huggingface dataset:
Protein: MNME_MAGSA
Sequence: MSETIYALASAAGRAGIAVWRLSGEGSGTALSALTGKPLPEPRRARRVRLRDGAGEVLDDGLVLWFPAPHSFTGEDVAELHLHGGRAVAAALTARLGELGLRPAEPGEFSRRAFLNGKLDLTRAEAIADLVDAETAAQRRQALRQLDGGLAGLVEGWRSALVRAMAHLEAVIDFADEDIPDTLLEQSVGEVRSLRREMEVHLDERRNGERLRDGIHITILGAPNAGKSSLLNRLAGREAAIVSAQAGTTRDVIEVHLDLGGWPVIVADTAGLRDSACEIESEGVRRAADRAAKADLRLCVFDGTLYPNLDAATLEMIDDATLVVLNKRDLMTGETPASINGRPVLTLSAKAGEGVDDLVAELARVVESRFAMGSAPVLTRERHRVAVAEAVAALSRFDPGLGIEMAAEDLRLAARSLGRITGRVDVEEILDVIFHEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN2_PSEU2
Sequence: MTATAQRQRPIDTTGAGQRAQQAELHPELNRAHVRFINLGKTYHGKQGPVEALGNIDLAVQHGEIFGIIGRSGAGKSSLIRTINRLEQPSNGRVLIDQVDIGEFDEDKLVELRRRIGMIFQHFNLMSAKNVWQNVELPLKVAGVPREQRARKVAQLLELVGLQDKHKAYPAQLSGGQKQRVGIARALVHDPAILLCDEATSALDPETTQSILGLLREINQRLGLTIVLITHEMAVIRDICHRVVVLEQGRIVEQGPVWQVFGDPQHEVSKTLLAPLQTGLPKEWAERLSDQPQRPDAALLLDVHFTGVSAEGPDLAALFTALGGKVELLQGGVERIQDRAIGHLILSVAGSPHSRDELLARARTLAPRAEVLGYVG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1008_CALMQ
Sequence: MVTVTLISKPQARVGGNFRVIKIPEECYRCKLYGICMGRLRPGRAYRITEVRPLKYPSPYKCLLNGDEMVPVVVEEENLILPIKLPYIIEGSITSFDKSWCICHPCPSEEALPSRVKIIKVIDRRQCGSGWFFLVEAKPLD
What are the official names of this protein?
UPF0179 protein Cmaq_1008.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: SECB_ECO24
Sequence: MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_STAAB
Sequence: MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_LACH4
Sequence: MSVKWKKTGKTTGELTFDISKDEIKLGLDQAFRRVKKNLHVPGFRKGHVSRVIFDQYYGEEALYEDALNIVLPNAYSAAVKEAGIAAVGQPQIVPVSMDKDKDWTMKATVTVEPEVKLGDYKGIEVPKQNTRVYQKDVDAELDKRREQNAELVLKKGKSAKGDTVTIDYKGTIDGKEFEGGSAENYSLELGSGAFIPGFEDQLIGHEAGDDVDVVVTFPKDYGAKDLAGKEAHFATKIHEVKSKQLPKLDDEFAKDVDDSVDTLDELKDKIKKQLKDQKEQAANDAIQEAAIEGAVKNATVDEIPDAMIQDDVDTQLNQYLGNMQRQGIDPQTYYKLTNTNEQQLRSQFAKNAAERVKTNLVLEAIVEKEGLKATKEEIDKEIKDLAAEYNMDEKTIRNTLSDDMLSHDITVRKAMDLVTDNAKQVAKAKLEAKEAEEAEDKEEAEDKKENK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CH601_MYCTU
Sequence: MSKLIEYDETARRAMEVGMDKLADTVRVTLGPRGRHVVLAKAFGGPTVTNDGVTVAREIELEDPFEDLGAQLVKSVATKTNDVAGDGTTTATILAQALIKGGLRLVAAGVNPIALGVGIGKAADAVSEALLASATPVSGKTGIAQVATVSSRDEQIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGIGFDKGFLSAYFVTDFDNQQAVLEDALILLHQDKISSLPDLLPLLEKVAGTGKPLLIVAEDVEGEALATLVVNAIRKTLKAVAVKGPYFGDRRKAFLEDLAVVTGGQVVNPDAGMVLREVGLEVLGSARRVVVSKDDTVIVDGGGTAEAVANRAKHLRAEIDKSDSDWDREKLGERLAKLAGGVAVIKVGAATETALKERKESVEDAVAAAKAAVEEGIVPGGGASLIHQARKALTELRASLTGDEVLGVDVFSEALAAPLFWIAANAGLDGSVVVNKVSELPAGHGLNVNTLSYGDLAADGVIDPVKVTRSAVLNASSVARMVLTTETVVVDKPAKAEDHDHHHGHAH
What is the function of this protein?
Involved in copper homeostasis (PubMed:32808291, PubMed:32812602).  Binds copper and may help maintaining copper homeostasis when copper is present in excess, notably in the macrophage phagosome, by acting as a metal storage protein (PubMed:32808291, PubMed:32812602).  Could be involved in copper resistance during mycobacterial biofilm formation (PubMed:32812602).  Protects from copper stress in vitro (PubMed:32808291).  Can also bind other metals, but binds copper with relatively higher affinity compared to nickel and cobalt (PubMed:32808291).  May play an important role in survival under low aeration by affecting the expression of genes known for hypoxia response (PubMed:26822628).
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OHRL2_STAS1
Sequence: MVKPLYETKVISNGGRDGKVFSEDNTFYQDLAVPKEMGGNGVTESNPEQLFAAGYSACFNNALMHILKSDSKGTIEPEVSVTAYLLPDKNDGGVKLAAELDVTLTDMTQEEAETYVEKAHNYCPYSKALKESIDIEIQVSVN
What are the official names of this protein?
Organic hydroperoxide resistance protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: SYL_SALSV
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGSVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_STRP3
Sequence: MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGGVAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDSSVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLDLETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLTLLLA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RFX2_XENLA
Sequence: MQNSDSGSDSATSVALRTSTSAQAPVVQPVPASQQVQTVQHVYPAQVQYVEGDTVYTNGAIRTAYSYNAETQIYAPSSGSSYFDSQGGGAQVTTVVSSPTAIPSHSMVGITMDVSGSQIISSSGAYLIHGGLENSRHTPSHTSRTFPATLEMAIENLQKNEGITSHKSSLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQDHKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRIQEDAQYMAIRQQPIHQKQRYRPAQKIDGMGENPANSSQHASPEQSVAAQSQHHQQFIDTSHVFPDFPAPDLGSLLLPEGITMTDIKNLQLMYRRHCEATIDVVMNLQFQYIEKLWQAFWNSKPSSPDGSNPMSSEDEQEPIIPNEKLMVLCKYEPIMRWMRNCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTNAMCDFPQQIVHAKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCDEGMVQKLEQDFKLTLQQQSSLDQWANWLDNVVTQVLKPHEGSTSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFSDFASMSPVQMDKDDVSELGSDTEGDPHISGQPPVKRERVELNHSMQEM
What is the function of this protein?
Transcription factor that acts as a key regulator of ciliogenesis.  Specifically regulates expression of genes required for cilium assembly and function.  Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PubMed:22227339, PubMed:24424412).  Required for neural tube closure and neural ciliogenesis (PubMed:22227339).
What are the official names of this protein?
DNA-binding protein RFX2, Regulatory factor X 2.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly expressed in the nucleus and at lower level in cytoplasm.
Protein: PTH_STRZP
Sequence: MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_ARAHI
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLLAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTNRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGVTAPGETASTSLTWGGGELVTVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: INO1B_XENLA
Sequence: MAEMFKVESPHVRYLKDVIEADYSYDTTQVYEEKGVTKVKPCSTKFTFHTERKVPKLGVMLVGWGGNNGTTVTAAVLANRLGLSWMTKTGKKVANYYGSLFQSSTVCLGRGSSGEVFVPFRDLLPMVNPNDLVFDGWDISSLNLADAMFRAEVLDWQLQEQLRPYMEKMKPRPSIYIPEFIAANQEDRADHTIHGTKAEQVQKIREDIQDFKRTSGVDKVIVLWTANTERFCDIIPGVNDTADNLLKAIENGLEVSPSTMFAVASILEGCAFINGSPQNTFVPGAIELAIRHNVFIGGDDFKSGQTKIKSVLMDFLVSAGLKPVSIVSYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVQSNPILYGPNEKPDHCVVIKYVPYVGDSKRAMDEYTSEIMMGGANTIVLHNTCEDSLLASPIFLDLVLLTELCQRITFRTETDQEFQTFHSVLSILSFLCKAPLVPAGTPVVNAFFRQRNCIENILRACLGLSPQNHMMLEHKMQRSFVSLKRPSVDCNAYPISSKKGNGVNGFHPPGISNGLSHSNGLGKTVISSDIEIEN
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.  Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).
What are the official names of this protein?
Inositol-3-phosphate synthase 1-B, IPS 1-B, Myo-inositol 1-phosphate synthase B, MI-1-P synthase B, MIP synthase B.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1751_STRPZ
Sequence: MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK
What are the official names of this protein?
UPF0297 protein Spy49_1751c.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: DNAJ_SALCH
Sequence: MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI5_FUSPS
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPYPAMLNYFGDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTMDFFEGCWIEQYNFGGFPGSDDYPQFLRRMNGLGHCVGASLWPKDLFDERKHFLEITSAVAQMENWMVWVNDLMSFYKEFDDERDQISLVKNFVTCHEITLDEALEKLTQETLHSSKQMVAVFSNKDPQVMDTIECFMHGYVTWHLCDARYRLHEIYEKVKDQDTEDAKKFCKFFEQAANVGAVAPSEWAYPPVAQLANVRAKGDVKEAQKPFLSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: KITH_PSHV1
Sequence: MGRIVVLYVDGAFGIGKTTVLRQIQKSAAYRFRRIYLEEPMRAWRSWFVDDHDAIREIYTTQELKDAGEIDLREASRRVCYAQVSLSAPFHIMNAVIYGIISGESEATSAHLGEGDYFVGVDRHPLASCLCFPVARFVTGYLEYTDLIALVATLPDYPRGASIAILDLSVEEQARRITERSRSGEHVNKTFLRILRNVFIIMYNTVAYLRNVSIDKACADREALEDFRGSQLESDMHKIDIQPRDDPNASETLFAVMASDATWRKNRKQSALFVYTMAKLDALLRSLNMHIVDINGLSQEQCAEKVVAISSKVPAVTARGNAPDLLFDAVEAYNADMGV
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: CHIN_RAT
Sequence: MPSKESWSGRKTNRATVHKSKQEGRQQDLLIAALGMKLGSQKSSVTIWQPLKLFAYSQLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF
What is the function of this protein?
GTPase-activating protein for p21-rac and a phorbol ester receptor.  Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
What are the official names of this protein?
N-chimaerin, A-chimaerin, Alpha-chimerin, N-chimerin, NC, Rho GTPase-activating protein 2.
Protein: PYRB_NEIM0
Sequence: MPNPLYRQHIISISDLSREQLECLLQTALKLKAHPRGDLLEGKLIGSCFFEPSTRTRLSFETAVQCLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAIIQRHPKDGAARVAAEFSRVPVINAGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAGDLKYGRTVHSLCQALKRWGCEFAFVSPPSLAMPDYITEELDEAGCRYRILGSLEEAAEWADILYMTRVQRERFDEQEFAKIQGKFNLEASMLARAKPNLRVLHPLPRVDEIHPDVDATPHAYYFEQATNGVYARMAILSLVLNEEV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GREA_BLOPB
Sequence: MKRIPMTLRGAEKLREELDYLRNVLRPEIIKNISEAREHGDLKENAEYHAAREQQGFCEGRIQEIESKLFNAHIIDITKLTTDDKVVFGATVGVENLDTTYRQTYSIVGDDEANLKEHMISINSPIARGLIGHKEGDIVRINTPKGKVRYKILQVKYC
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RS17_STRZT
Sequence: MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LPXC_SHELP
Sequence: MIFQRTVKEMVKTTGVGLHSGNKVTLTIKPAPVNTGIVLVRTDLTPSVAIAAKADQVRETTMCTALVNDEGVRISTIEHLFAALAGLGIDNATIEVDAPEIPIMDGSASPWVFLLQSVGIQEQSAAKKYLRIKRPVRVEDGDKWAELRPFKGFRVDFAIDFNHPEIARSQQHMVMDFSSSAFVRDISRARTFGFMRDIEYLRANNLALGGSMENAVVLDEYRVLNPDGLRYEDEFVKHKILDAFGDLYVAGHAIVGEFRAFKTGHALNNQLVRALLAEQDAWELVSFEKEEEVPVSFAVPAGAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: METK_PELTS
Sequence: MARRLFTSESVTEGHPDKIADQISDAVLDAIFEKDPLARVACETLVTTGLVLVAGEITTDCYVDIPRVARETIREIGYTRAKYGFDCDTCAVITSIDEQSSDIAQGVDRALEVRERYGNEDELEATGAGDQGMMFGYATTETPELMPLPISLAHRLARRLAEVRKSRLLPYLRPDGKTQVTVEYENGRPVRVDTIVISTQHHPRVTLDEIRSGVLEHVVKPVVPPEFLDGSTRFFVNPTGRFVIGGPQGDTGLTGRKIIVDTYGGMARHGGGSFSGKDPTKVDRSASYAARYVAKNIVAAGLAEKCEFQVAYAIGVAHPVSMMVDTFGTGRVDEQTLVKLVKEHFDLRPAAIIKELDLRRPIYRQVSVYGHFGRNDLDLPWERTDKAEALRRGAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y069_CHLTR
Sequence: MLSCIFQDTIFLSSFLAVSLICMTTALWGTILLVERQPLLSESLSHACYPGLLIGALLSYKVPAFSDSLWVIIFFGCLASVLGCLGISFLEKKLAMHKDSALCLVLVSFFGVGVILVSYVKDCCPLLYNKINAYLYGQAATLGYTEAKLALIIFCLSAVVLWWWYRQISVAIFDREFAYSCGLRTRTAELVVLVFISLVIVSGVRSVGILLISAMFVAPPLSARQLSDRLSTILILSSIFGGICGALGCYFSVAFTCQTVVEGKPISIILPTGPLVVFFAGVLVFLCLIFSWKTGWITRYFRRKWFLFSRDEEHLLKIFWYLREQNTYQVGMRDFVRSRKYQEYFGDKVFPRFRMFLLCKKGLVSCSEHQWSLTDKGLARAAKLVRAHRLWESYLVSQLDFNKNEVHHFAEEMEHVLTDELDSTLSQMLQDPDYDPHQREIPKRTRKSDGC
What is the function of this protein?
Part of an ATP-driven transport system CT_067/CT_068/CT_069/CT_070 for a metal.
What are the official names of this protein?
Probable metal transport system membrane protein CT_069.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TX332_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMFDDFDQADEDELLSLIEKEEARAEECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAAGKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1p, Toxin-like structure LSTX-B32.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_DESHD
Sequence: MNSNTIKTGIDRAPHRSLLKALGLTDRELSKPFIGVVNSFTELVPGHMHLRQVTEAVKAGIRENGGTPFEFSTIAVCDGIAMGHEGMHYSLASREIVADAIEVMAKGHQLDALVLIPSCDKVVPGMLMAAMRLNIPAIVVSGGPMLPGRFEGNPVTLSTVFEGVGQVHAGKKDEAWLHELEAKACPTCGSCAGMFTANSMNCLTEALGMALPGNGTIPAVYSERLVLAKETGYQVMELYRQDLKPRDIVTQSTLKNGVAVDMALGCSTNTILHLPAIANEGDIDWDLGKVNEVSEKTPQICKLAPASETPLAALHEAGGVSAVLKQLLDAGLIDGSTMTVSGVTMAERLKDAKVVDTEIIRPQSNPFSQRGGLRILFGNLAPEGAVIKQGALSSQDFVFEGSAKVFNGEVPAAEAIRNLEIKAGDVVVIRYEGPKGGPGMREMLGPTATLAGMGLDSDVALLTDGRFSGASRGLSIGHVSPEAALGGDIALLKDGDKIRIDIGKGRLEWIVSEEEREQRRQEFAAMAVKPDHLKPELRQGYLGRYAYFVQSASKGAALRRVKE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.