PharMolix/UniProtQA huggingface dataset:
Protein: LEU3_SHEON
Sequence: MSYQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLRSDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREISRIARIAFEAARGRRKKVTSVDKANVLACSVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQILSAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIADAVKAGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL7_CRYNB
Sequence: MTATHTHSNGSNDFTPVSINDHVHRRFNPLLGKHVLVSPHRSLRPWNGQKETPAIPVETPHDSKCYLCPGNKRTTGQHNPDYKGIYVFENDFPALLPDPLAVGTNKISDDPLFQSEPVRGRCKVICFHPRHDLTMAAMRISEINHVLDGWKDVYAEEGKIMQEESSDGCVQIFENRGAMMGCSAPHPHGQVWTTSFVPDEPATEIENFVRYASGRSGSHMLLDYALREVKARERVVTLHESGWVAVVPYWAAWPFEILLMPYKRHIPSILQLTAEEQTGLATILKDVLSRYDNLFSCPFPYSMGLHQSPLPPTDPTSNSAQVHFHFYPPLLRSATVRKFMVGFELLGEAQRDIVPEQAAVRLRESLPHKRATLSNDKPYNP
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: RS3A_NOSCE
Sequence: MAIQPPGSNTKANKKGAKKNLKIDTFSKKEWYNLKAPAIFPNNVCGKTMVTKSSNKQNLALLLIGRKFDINQADLTGNLEEHARKFSFRVNEVRGKDCIGVFDGMHMTSDKVKGIIRKWHTLIEAEKDIVAKDGTILRVFVNAVTKKTPTCTSKRVYCKTSEEKKIRKVMFDVIEEELKGEDLNKIMKKLAAEVIGKSVEKKGSLIYPLQNCCVIKVKTVKRGKDTSNAMEIEAN
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_BURCJ
Sequence: MFQGASALTLDAKGRMSVPARYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYNAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y2001_MYCTU
Sequence: MHHNRDVDLALVERPSSGYVYTTGWRLATTDIDEHQQLRLDGVARYIQEVGAEHLADAQLAEVHPHWIVLRTVIDVINPIELPSDITFHRWCAALSTRWCSMRVQLQGSAGGRIETEGFWICVNKDTLTPSRLTDDCIARFGSTTENHRLKWRPWLTGPNIDGTETPFPLRRTDIDPFEHVNNTIYWHGVHEILCQIPTLTAPYRAVLEYRSPIKSGEPLTIRYEQHDDVVRMHFVVGDDVRAAALLRRL
What are the official names of this protein?
Uncharacterized protein Rv2001.
Protein: Y023_METJA
Sequence: MKSIRISSDYRAKRDNASCFDETFLKSFAEELYNAIIEIIKENKTIIKNEVRDELRNELATKEDILLVEERLGKKIELLNQKIEREIKLVRRDMIIINLVIILAMYAPEIIGKLLIFR
What are the official names of this protein?
Uncharacterized protein MJ0023.
What is the protein family that this protein belongs to?
Belongs to the M.jannaschii MJ0023/MJ0349/MJ1072/MJ1074/MJ1107/MJECL16 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y444_DEHM1
Sequence: MSGHSKWATIKHAKGAADAKRGQLFTKLSREIIFAAKQGGPSPEGNARLRLAIQKAKDNRMPSDNIERAIKKGSGELEGATVIEIILEGYGPGGVAVLVNGMSDNRNRTVSDVRHMFSKSGGSLAESGAVSWIFETKGVIGVETVGLDTDELSLKAIDMGAEDVNIEEDYMEIYTAMPDMEKVRQQLEAQGVTVDSAEINMIPKNTVKLDEETSLQVLKLLDKLEELDDVQTVSSNADFDPEVVEKYHSQA
What are the official names of this protein?
Probable transcriptional regulatory protein DET0444.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BURP6
Sequence: MDHIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMESQVLDSMDLERERGITIKAQTAALTYRARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPAANPENAIAEIEDVIGIDAMDAVRCSAKTGLGVEDVLESLIAKVPPPKGDPDAPLQALIIDSWFDNYVGVVMLVRIVNGTLRPKERIKLMATDAQYAVEHVGVFTPKSRNLESLSAGQVGFIISGIKELTAAKVGDTVTHATKPAPEPLPGFKEVKPQVFAGLYPVEANQYDALRESLEKLKLNDASLQYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVVYEVVQSDGTTIMVENPAKMPEPARIAEIREPIVTVNLYMPQDYVGSVITLCEQKRGTQINMQYHGRQVQLTYEIPMAEIVLDFFDRLKSVSRGYASMDYEFKEYRTSDVVKVDMLINGDKVDALSIIVHRSQSQYRGREVAAKMREIIPRQMYDVAIQAAIGAHIIARENIKALRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKQVGSVEIPQEAFLAILRVEDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SURE_DEIGD
Sequence: MTALPSPDRPRILVANDDGIFSPGIKALALALADVGDVVVVAPDVEQSAVGHGITIRRPLRFKHTASAGFGTLPAYRVDGTPADCVVLGVHLLGRPDLVVSGINLGSNLGDDLTHSGTVAAAIEGLALGLPSIAFSQQGNGGGEYSFTAGAAYAARLARAVLAKGLPPRVLLNVNFPAGLPRGVRITKVGEHRWEDSIITRHDPEGREYHWVAGQSRAADAHDPDTDYGAVQAGYVSVTPVRLDLTARDLLGELAGYVPEI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_VIBVY
Sequence: MNDQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDVIEAGFPVSSPGDFESVQTIARNIKNSRVCALSRAVEKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVEMGVRAVKHARKYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAVQAGARQVEGTINGIGERAGNCSLEEIAMIIKTRQELLGVRTGINHEEIHRTSKLVSQLCNMPIQANKAIVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDAMGYKEDEYNLDALYQDFLKLADRKGQVFDYDLEALMHFSNLREEDDYYKLNYLSVQSGSVMATTSIKLLCGDEEKCEAAVGNGPVDALYQCIYRLTGYDIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGISTDIVEASGQALLHVINSIHRADEIAEMKQKKIATV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: DAPF_THEMA
Sequence: MCYSANGNTFLIVDNTQKRIPEEKKPDFVRENVGDLDGVIFVELVDGKYFMDYYNRDGSMAAFCGNGARAFSQYLIDRGWIKEKEFTFLSRAGEIKVIVDDSIWVRMPGVSEKKEMKVDGYEGYFVVVGVPHFVMEVKGIDELDVEKLGRDLRYKTGANVDFYEVLPDRLKVRTYERGVERETKACGTGVTSVFVVYRDKTGAKEVKIQVPGGTLFLKEENGEIFLRGDVKRCSEE
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (PubMed:30548096).  Also catalyzes the racemization of certain amino acids, including Lys, with low efficiency (PubMed:30548096).
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, Dpm epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_THEMA
Sequence: MKEWRRNILGRELVVQYGKVAKQSSGSALVRFGDTVVLATANISDKAVEGIDFVPLTVEFQERFYAAGKIPGGFIKREGKPSESAILSARLIDRPIRPLFPKKLRNEVQVIVTVLSVDPNVPPDVVGIFAASLALNVSKIPFEGIVAGIRVGYRDGQFIALPSEEDIEKGLMDITVAGTKDAVTMVEGEAKEVTEEDMVKALRFAHSVIKELVDFQEEILSEFNVEKIPVVEPTPPEGLVEAFKDLLNKEELERRILVKVKKEREVALKEYEEQLLNQIAEKLSVTDLEGIKPFVSELYEDAVKKTMRRLIVEKGIRADGRKPTEIRPISCEVGLFPRTHGSALFTRGETQSLGIVTLGAPMDVQIIDTLLEEGVKRFMLHYNFPPFCTGEVKPLRGPSRREIGHGHLAERALKNMLPPEEEFPYTIRVVSEILESNGSSSMATVCSGSLALMDAGVPIKKHVAGIAMGLILEEDAEIILTDIIGMEDHYGDMDFKVAGTRDGITAFQMDCKVSGVSDELLMKALMQAREARMYILDRMYETISAPRPHLSKYAPIIKVTKVDPEKVADVIGPGGRVIKKIIKDFDVKVEIDDETGLVKVVGSSEENVDKAIELIREIAKEIEVGEVLEGKVTRIEPYGLFIEVRPGKIGLLHQSKVGEDMRQFLKKVKVGDTIKVQVINIDDLGRLQFKRVTEGENTQHGKTHSKRN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_MANSM
Sequence: MEIFMPKLRSATSTQGRNMAGARSLWRATGMKEGDFGKPIIAVVNSFTQFVPGHVHLHDIGQMVVKQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPTIFVSGGPMEAGKTKLSDQLIKLDLIDAMIQSADKNVSDSDVDAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSCLATHADRKQLFLDAATQIVELCKRHYEQDDYSVLPRSIATKAAFENAMSLDIAMGGSTNTVLHLLAVAQEAEVDFTMADIDRLSRIVPCLSKVAPNTNKYHMEDVHRAGGVMAILGELDRANLLHHDTKTVLGLTFAEQLAKYDIKLTRDEAVKTFYRSGPAGIRTTEAFSQDCRWETLDDDRENGCIRDKAHAYSQDGGLAMLSGNIALDGCIVKTAGVDESILKFTGEAIVFESQEDAVDGILGGKVKAGHVVVIRYEGPKGGPGMQEMLYPTSYLKSMGLGKACALLTDGRFSGGTSGLSIGHCSPEAASGGTIGLVRNGDIIAIDIPNRSIQLQVSDEELATRRAEQDVKGWKPANRAREVSFALKVFGHFATSADKGAVRDKTKL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SPB4_YEAST
Sequence: MSKSLEWDNLGFSLLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEKVVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVLDFLQMPAVKTSACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSKNQAPSSLKLNYCVVNPAEKLQLLVSILNNYKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTDSLSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELDLEVKGITTNFYEDFRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLATEKQEGIFPGNWLVDPPVNMDEYKYKDKKREKERQETLKNISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLKRKAIEEELKAEELDENAEEERIKEDWKEIVLQNKRKKVSSKAIQGNFDDL
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits (PubMed:2408148, PubMed:25579579).  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA (PubMed:21825077).  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2 (PubMed:9769101).  Also required for recruitment of NOG2 to pre-ribosomes (PubMed:22735702).
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4, Suppressor of PAB1 protein 4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IF1_MYCGE
Sequence: MKNDKLFLTGKILEIIHGDKYRVMLENNVEVDAHLAGKMKMKRTKILPGDVVEVEFSPYDLKLGRITQRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_GEOMG
Sequence: MYAVVRTGGKQYKVSEGDFLKVEKLEGAVGDTIELKDILMVGGETVKIGTPLVPSASVVGKIVEQGKDKKILVFKSKKRKDSKKLRGHRQPRTVLKIEKING
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: THIK_SALTI
Sequence: MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTHRIVLRRHHDPDAPPAHFLRHHRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: ANF_PIG
Sequence: MSSFTITVSFLLVLVFQFPGQTRANPVYGSVSNADLMDFKNLLDHLEDKMPLEDEAMPPQVLSEQNEEVGAPLSPLLEVPPWTGEVNPAQRDGGALGRGPWDASDRSALLKSKLRALLAAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY
What is the function of this protein?
May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation.  In vivo promotes natriuresis.  In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
What are the official names of this protein?
Natriuretic peptides A, Atrial natriuretic factor prohormone, preproANF, proANF, Atrial natriuretic peptide prohormone, preproANP, proANP, Atriopeptigen, Cardiodilatin, CDD, preproCDD-ANF.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
[Long-acting natriuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Vessel dilator]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Kaliuretic peptide]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Urodilatin]: Secreted. Note=Detected in urine. Not detected in blood. Increased electrolytes, osmolality and intracellular cAMP levels increase peptide secretion/excretion. SUBCELLULAR LOCATION: [Atrial natriuretic peptide]: Secreted. Perikaryon. Cell projection. Note=Detected in blood. Detected in urine in one study. However, in another study, was not detected in urine. Detected in cytoplasmic bodies and neuronal processes of pyramidal neurons (layers II-VI) (By similarity). Increased secretion in response to the vasopressin AVP (By similarity). Likely to be secreted in response to an increase in atrial pressure or atrial stretch. In kidney cells, secretion increases in response to activated guanylyl cyclases and increased intracellular cAMP levels. Plasma levels increase 15 minutes after a high-salt meal, and decrease back to normal plasma levels 1 hr later (By similarity). SUBCELLULAR LOCATION: [Atriopeptin-3]: Secreted. Note=Detected in blood. Slight increase in secretion in response to the vasopressin AVP.
Protein: PHNX_BACC2
Sequence: MKIEAVIFDWAGTTVDYGCFAPLEVFMKIFHKRGVEITVEEARKPMGLLKIDHVRALTEMPRIADEWKRVFGQLPTEVDIHEMYEEFEEILFSILPSYATPIEGVKEVIASLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELDVYPMNHMIKVGDTVSDMKEGRNAGMWTVGVILGSSELGLTEEEVESMDSVELREKIEVVRNRFVENGAHFTIETMQELENIIEHIEKQELIIS
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: APAH_XANAC
Sequence: MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEEQRKVNPDLLRIVMAEDRDALLDWLRMQKLAHVDRELGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQPGWSPGLSGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGVHAIDTGAVWGGKLTALQLDTDELRVVQVPGNPITHPPKTAQRPRQPRRRQRQRGGDQAQTGPAPTPASTGPAGG
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: FXYD6_MOUSE
Sequence: METVLVLCSLLAPVVLASAAEKEKEKDPFYYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITTNAAEPQKAEN
What are the official names of this protein?
FXYD domain-containing ion transport regulator 6, PLM-like protein, Phosphohippolin.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y1727_BACLD
Sequence: MVKVERLLINYKTLEEFKKFREYGIQELSMLEDLESNMIENDSNSPFYGIYYGNRLVARMSLYKVDGKSNQYFEEGQDYLELWKLEVLPGYQRNGYGTMLVEFAKSFGLPIRTSPRVKSSDFWNKMGFTPVKYDMARDKGENPLVWHPASEPSQSSESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BLi01727/BL05157.
Protein: CLPP1_PROMA
Sequence: MIPIVVEETGRGERAFDIYSRLLRERIVFLGEQVTNDSANRIVAQLLFLEAEDPEKDIFLYINSPGGSVYDGFGIFDTIQHIKPDVHTVCVGLAASMGAFLLCAGAKGKRSSLQHSRIMIHQPLGGARGQATDIRIQADEILFLKQKLNTELSNRTGQPLSKIAEDTDRDFYMSPSEAISYGIIDNVLNKKPVSVL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCL1_YEAST
Sequence: MARRKNFKKGNKKTFGARDDSRAQKNWSELVKENEKWEKYYKTLALFPEDQWEEFKKTCQAPLPLTFRITGSRKHAGEVLNLFKERHLPNLTNVEFEGEKIKAPVELPWYPDHLAWQLDVPKTVIRKNEQFAKTQRFLVVENAVGNISRQEAVSMIPPIVLEVKPHHTVLDMCAAPGSKTAQLIEALHKDTDEPSGFVVANDADARRSHMLVHQLKRLNSANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDWNTQAGLGLHAVQLNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRLVNCDDKLPGLIRSKGVSKWPVYDRNLTEKTKGDEGTLDSFFSPSEEEASKFNLQNCMRVYPHQQNTGGFFITVFEKVEDSTEAATEKLSSETPALESEGPQTKKIKVEEVQKKERLPRDANEEPFVFVDPQHEALKVCWDFYGIDNIFDRNTCLVRNATGEPTRVVYTVCPALKDVIQANDDRLKIIYSGVKLFVSQRSDIECSWRIQSESLPIMKHHMKSNRIVEANLEMLKHLLIESFPNFDDIRSKNIDNDFVEKMTKLSSGCAFIDVSRNDPAKENLFLPVWKGNKCINLMVCKEDTHELLYRIFGIDANAKATPSAEEKEKEKETTESPAETTTGTSTEAPSAAN
What is the function of this protein?
Methylates cytosine to m5C at several positions in different tRNAs and pre-tRNAs containing intron.  Able to modify tRNAs at all four positions (34, 40, 48 and 49) at which m5C has been found in tRNAs.  May be involved in ribosome biogenesis as its disruption leads to increased sensitivity to the antibiotic paromomycin.
What are the official names of this protein?
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase, Multisite-specific tRNA:m5C-methyltransferase, tRNA (cytosine-5-)-methyltransferase NCL1, tRNA methyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSBP_SOLLC
Sequence: MAASTQCFLHQYHALRSSPARTSSVSSPKPNQLICRAQKQDDASNAAVSRRLALTLLIGTAAIGSKVSPADAAYGEAANVFGKPKENTDFLPYNGDGFKLQVPAKWNPSKEVEYPGQVLRYEDNFDSTSNLIVAVTPTDKKSITDYGSPEEFLSKVDYLLGKQAYFGKTDSEGGFESGAVATRNLLEASSATVGGKEYYYLSVLTRTADGDEGGKHQLITATVNDGKLYICKAQAGDKRWFKGAKKFVENAATSFSIA
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: RUVC_SALNS
Sequence: MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PDAC_BACSU
Sequence: MLAKRIKWFHVLIAVVCVVGLIGFFHNHSLKKETVMNKVRTDSQYGNVEIATLVNDGKTFNYAVNYPVFKNEKMDSALKRFAEKEVRQFQKETKDVDQEHTTKRNELNVDYKIVHYAKQTVAIVFNEYKYIGGAHGQTVKKTFNYDFSKQAFLSIDDIFKEDADYLHKLSLIAYHELKKNKDIAADDALLKEGTAPKKENFSRFAIKEDYIELYFDTYQVAAGYLGEQSIAIKKSLLKDILKEQYIDKAKNKNKIKEQKPKHEVISLPKEETVDPNQKVIALTFDDGPNPATTNQILDSLKKYKGHATFFVLGSRVQYYPETLIRMLKEGNEVGNHSWSHPLLTRLSVKEALKQINDTQDIIEKISGYRPTLVRPPYGGINDELRSQMKMDVALWDVDPEDWKDRNKKTIVDRVMNQAGDGRTILIHDIYRTSADAADEIIKKLTDQGYQLVTVSQLEEVKKQREAK
What is the function of this protein?
Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan, a modification that confers resistance to lysosyme.  Is not able to deacetylate N-acetylglucosamine (GlcNAc) residues in peptidoglycan, but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5.  Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer).  Does not deacetylate GlcNAc.
What are the official names of this protein?
Peptidoglycan-N-acetylmuramic acid deacetylase PdaC, Peptidoglycan MurNAc deacetylase, Polysaccharide deacetylase PdaC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.