PharMolix/UniProtQA huggingface dataset:
Protein: SIL1_DEBHA
Sequence: MKLSKGVLSSILLTLLIKPIESSIVNTDGELICAPNNPTDCYPKIFEPTTEWQTIREGQDIPAGLHVRLNMENLAREAKILDPSEETEGSSELMVNAEQNNDNGDNSHQMTNEDQANEIQQKIKEFKQTQGKSKVSTVDLNDFQSSVDEVQHYREGGDANRLSTALDTLIDLSHDIEFGVKLTQDSSVFRSLVDVSKSVQDEDLQEKVYRIMGSSLRNNPDAVNHVLKNQDATFVECLFDKLDTDASDVIKKRILGIIHALTQNSHFNAKYFNSNNANSAVDSLISVFPSLESQSQTRLMNILEDLKLLGGANSNEKRAIEESADPKSQYSHFLQHSLADSGVASEDQFKLYFNKLSEVHSQDKSLKPSKAFMEWLSKEAELRSKGNKERDSSYTEEDRQFDQDLLRARHVVFGNPMGLRKALADEL
What is the function of this protein?
Required for protein translocation and folding in the endoplasmic reticulum (ER).  Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).
What are the official names of this protein?
Nucleotide exchange factor SIL1.
What is the protein family that this protein belongs to?
Belongs to the SIL1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PTH_STRPD
Sequence: MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNFKAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKLRLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAISLTLDRVVNAVKFYLQENDFEKTMQKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_STRZJ
Sequence: MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TNF12_HUMAN
Sequence: MAARRSQRRRGRRGEPGTALLVPLALGLGLALACLGLLLAVVSLGSRASLSAQEPAQEELVAEEDQDPSELNPQTEESQDPAPFLNRLVRPRRSAPKGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH
What is the function of this protein?
Binds to FN14 and possibly also to TNRFSF12/APO3.  Weak inducer of apoptosis in some cell types.  Mediates NF-kappa-B activation.  Promotes angiogenesis and the proliferation of endothelial cells.  Also involved in induction of inflammatory cytokines.  Promotes IL8 secretion.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 12, APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted. SUBCELLULAR LOCATION: [Isoform TWE-PRIL]: Cell membrane; Single-pass membrane protein.
Protein: PSOE_ASPFU
Sequence: MVFGTLYTFPGDQCRTIAIKAVAKANGLDLDIRETPRTPDHLSISKLGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVVEEYLQDRTFLVGDQLSLADLFCAGNISLGFQFFYGKAWRQQNPNVSRWYEMVCHQPIYAAVTDKFQLLDEPKLTNNPPEKKPETVPKNGAAVAIEATQA
What is the function of this protein?
Glutathione S-transferase; part of the gene cluster that mediates the biosynthesis of pseurotin A, a competitive inhibitor of chitin synthase and an inducer of nerve-cell proliferation (PubMed:24082142, PubMed:24939566).  The PKS-NRPS hybrid synthetase psoA is responsible for the biosynthesis of azaspirene, one of the first intermediates having the 1-oxa-7-azaspiro[4,4]-non-2-ene-4,6-dione core of pseurotin, via condensation of one acetyl-CoA, 4 malonyl-CoA, and a L-phenylalanine molecule (PubMed:24082142, PubMed:24939566).  The dual-functional monooxygenase/methyltransferase psoF seems to be involved in the addition of the C3 methyl group onto the pseurotin scaffold (PubMed:24939566).  Azaspirene is then converted to synerazol through 4 steps including oxidation of C17 by the cytochrome P450 monooxygenase psoD, O-methylation of the hydroxy group of C8 by the methyltransferase psoC, and the trans-to-cis isomerization of the C13 olefin by the glutathione S-transferase psoE (PubMed:24939566, PubMed:27072782).  The fourth step of synerazol production is performed by the dual-functional monooxygenase/methyltransferase psoF which seems to catalyze the epoxidation of the intermediate deepoxy-synerazol (PubMed:24939566).  Synerazol can be attacked by a water molecule nonenzymatically at two different positions to yield two diol products, pseurotin A and pseurotin D (PubMed:24939566).
What are the official names of this protein?
Glutathione S-transferase psoE, Pseurotin biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: RL35_CORK4
Sequence: MKQKTHSGIKKRIKKTGSGKLRREQANRRHLLEGKPSTRTRRLKGDTSVSRNDTKRVNRLLGEG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PUP_CORK4
Sequence: MEKSSQIHGSKPGDDNADEPENAAGQSQIRKQGADDLLDEIDGLLESNAEEFVRSYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: KAX85_ODODO
Sequence: MSRLYAIILIALVLNVIMTIMPDSKVEAVSCEDCPEHCSTQKARAKCDNDKCVCESV
What is the function of this protein?
Selectively inhibits voltage-gated potassium channels Kv1. 2/KCNA2 (IC(50)=183 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 8.5, OdK1, Potassium channel toxin KTx7, ODKTx7.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YR458_MIMIV
Sequence: MNSDQENINSYNFESIKIGDYKCNVNRIPGDNLYLLSNFNDAEPKYDDKNGVHLEFNYKKIGESKTMRLNDGATSTVLIEGARNMNANEYFPKFVEKKKSFAEHLIRKTFAKGYESPSEIQALVVPELIQRKDTLIQFKSGTGKTHAFLFGCLWGFDPDDDVLQYIFITSSHEVATQIYEQAVFLLPETAKIALCIGQKKSPNSFGNSGFKTPIGTSSLNHKPKSIKEEREEIRQAQIIICTMGRFYDILCNKGWITTTRYLKAICVDEFDNIVASKTKQRSSTVMNTEDQMAEIIQKIESEAPKNSENGAQRVFFSATVSPYAIKIANSYFRKYSPIIGEPFIVLLDSEDYTLEGIRQYYVQCSNYFEKKEIILDLLKQCRIAQAIIFANRIETANEIKKLLDEQEVPISSAVFHGDLPAVTRKNIHKDFVENKIRLLISTDLTSRGLDVQGINVVFNFDMPDTLETYIHRVGRSGRYGRKGVSISLILVNQNKNEMEKVEQIDNCSKQSKMSQLPGDLSTLL
What is the function of this protein?
Putative ATP-dependent RNA helicase.
What are the official names of this protein?
Putative ATP-dependent RNA helicase R458.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: LSPA_BURA4
Sequence: MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFSLVLVYNRGAAFGFLSTASGWQRWAFTALGIGATLVICFLLRRHGQQRLFSLSLALILGGALGNVIDRLVYGHVIDFLDFHVGGWHFPAFNLADSAITVGAVLLVYDELRRVRGSR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_CUPTR
Sequence: MNKIRKGDEVIVLTGKDKGKRGTVQAVLGDKVAVQGVNIAKKHARPNPMLGTTGGVVDKVMPLHISNVALVDANGKPSRVGIKVEDGKRVRVLKTTGAVVAA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: COBT_ACET2
Sequence: MLFQTLKSIGELYKEPMDMVQRRLDSLSKPLGSLGRLEDIIKKLAGITGEVFPCVDKKAVIIMCADNGVVEEGISSCPKDVTSKVTRNFLKGITAINAFAKHTGSDIVVVDIGVDDDMDCEGIVKRKVRKGTWNIAKGPAMTRKEAIEAIEVGISIVEELGRKGVNLLGTGEMGIGNTTTSSAVSTVLTDSKAENMVGRGAGLSDEALKRKISIVKKAIDLNRPDANDPIDVVSKVGGFDIAGLAGCFIGAAACRIPILIDGFISATAALAAVRMEPKVKNFIFPSHGSAEPGSKKVMEALGFEPILNLEMRVGEGTGAALAFHIFDCAVSVYRNMGTFEDACIEQYQPQV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: MNME_PSEMY
Sequence: MNHARDTIAAVATAQGRGGVGIVRVSGPLSGQLAQAICRRELKPRFAHHGPFYGEQELPLDEGLAIYFPGPNSFTGEDVLELQGHGGPVVLDLLLRRCLELGARLARPGEFSERAFLNDKLDLAQAEAIADLIEASSEQAARNALRSLQGEFSKRVHALTESLIQLRIYVEAAIDFPEEEIDFLADGHVLSQLDGVRADLSTVLREAGQGALLRDGMTVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHVVDTAGLRDTDDQVERIGVERALKAIGEADRVLLVVDSTAPEAADPFALWPEFLEQRPDPARVTLIRNKADLSGEAVTLQTSADGHVTLSLSAKSADGLELLREHLKACMGYQQTAESGFSARRRHLEALHQAEQYLEHGRNQLTLMGAGELLAEDLRMAQQALGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_NOSP7
Sequence: MGQKIHPVGFRLGITHEHQSRWFAVPDRYPELLQEDYKLRQYIEQKLGRLAQNNAGISEVRIERKADQIDLEVRTARPGVVVGRGGQGIESLRTGLQGLLGSNRQIRINVVEVQRVDADAYLIAEYIAQQLERRVSFRRVVRQSIQRAQRAGVQGIKIQVSGRLNGAEIARTEWTREGRVPLHTLRADIDYSYCTAKTVYGILGIKVWVFKGEIIPGQEPDPLPPASRDRERDPRDRDREPRRRQQQRRRQQFEDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y065_METJA
Sequence: MRIGVVIHGPEIIDSGYALKIINLLKKFGEVKAKLGGTMGRVAVIDNNLQDIIDISEKLMPSQSLKKLANNDILILMNYGKSKITGHTFGKIVVERANLNKPIIQIERPGEEDGTIIIWNDDNSKIVKEIANYLSKELNLKIEKCISNGLEVWEKEGRVFRKVHGVDVGEAILVNGIVVGKAKSNEVILIAENGKLVDIIGGELKEGGIEKLKNVDLKKAVIKTGILRRHPTNPKIESKEIDEGYTIIINHAGEDVIEMIKNKGVVAVITIGDDTTTICGDILARFGIKIIGITDGDRDEILKNPVILKGSVIFLIKNMRDDDVGRILEKNLNLNKKYCYQELLDEVKKIFNDNNICYEEFVY
What are the official names of this protein?
Uncharacterized protein MJ0065.
Protein: FRMA_ECOL6
Sequence: MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTEXCGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFELARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
What is the function of this protein?
Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent.
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_PYRNV
Sequence: MRVLYLHTERFSWEVKEPALDIRDEPVSGGASNALVVFTTVERGDVPEEGFLRQIARDIVEVAEKVKASSIVIYPYAHLSNELARPYAAREIVNKLYEVVKSEFRGEVYKAPFGYYKAFELKCLGHPLSELSRSFKPGDSRAEKKAEERRDLYIVITPSGEEHDPAKFNYDGYEDLKILVEKEVFKRELGGGSEPRYLEYMRKFGFEWEPMSDVGHMRYAPEATLMMELVEDYAYAVAKSLGIPVFKIRGTNMFKLSERAIESHARLFGERLYIVESDTDLILRYAACFQQFAMVKDWVISYRQLPFGMLEVADSYRLEQPGETVLLFRLRRFYMPDLHIFTKDLAEAMEVTFRLHEAIFREIGKLGRTYVSLYNVTEDFYKAHRQYLVELARREGKPILVRVLPGQKYYWVLNVEFHIIDELGRPREIATFQIDVGNAQRFGIKYVDENNQTRYPVIIHTAILGSVERYLYAVFDTLARAEKEGKAPRLPTWLSPVQVRIIPITRDNLKYAVEVADKFEAEGIRVDVDDRDETLSKRIRDAEVAWVPYICVVGSKEEAEGVVSVRERGGGQYRVKPEDLIKKIREDVRGYPNRPLYMPRFLSQRPTRS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAB2_ARATH
Sequence: MSVDFSSERVCYVHCSFCTTILAVSVPYASLFTLVTVRCGHCTNLLSLNIGVSLHQTSAPPIHQDLQPHRQHTTSLVTRKDCASSSRSTNNLSENIDREAPRMPPIRPPEKRQRVPSAYNRFIKEEIQRIKACNPEISHREAFSTAAKNWAHFPHIHFGLKLDGNKKGKQLDQSVAGQKSNGYY
What is the function of this protein?
Involved in the abaxial cell fate determination during embryogenesis and organogenesis.
What are the official names of this protein?
Putative axial regulator YABBY 2.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUT_MYCGI
Sequence: MSTSLAVVRLDPDLPLPSRAHDGDAGVDLYSAQDVELGPGERALVPTGVAVAIPHGMVGLIHPRSGLAARVGLSIVNTPGTVDAGYRGEIKVCLINLDTSTPITIGRGDRIAQLLVQRVELPELVEVTSFDEAGLADTTRGDGGYGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SYGA_SALPA
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPENIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_RHOOB
Sequence: MTDLPAQLERVHMVGIGGAGMSGIARILLARGGQVSGSDAKESRGVLALRARGAQVRIGHDAGALDLLPGGPTVVVTTHAAIPKDNPELVEAARRGIPVILRPAVLASLMQGHRTLLVSGTHGKTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYDPNVVVVTNVEADHLDYFGSPEAYIQVFDDFAARLSHGGLLVACLDDPGSAALAQRVAARGLPGVRVLGYGSAEDADGAFAPIDGVEVGARLLSFEARDVGGVLQFQLAGEQAPRTIRMNVPGRHMALNALAALLAAREAGADVDEILEGIAGFGGVHRRFQFTGREHGVRVFDDYAHHPTEVRAVLGAAADLVSQPHEADRRESEEPVRSGKVIVVFQPHLYSRTATFAEEFGHALDLADEVMVLDVYGAREEPLPGVSGALVALSVSKPVHYQPDLSQAPRQVAALASPGDVVITMGAGDVTMLGNQILDALRAAPHHHPSR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ZYMMO
Sequence: MAHKKAGGSSRNGRDSAGRRLGVKKFGGESVIGGNIIIRQRGTKVYAGRNVGMGKDHTLFATAEGRVVFHKGKLGRSYVSVDALPLAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: TERD_ALCSP
Sequence: MSVSLSKGGNVSLSKTAPSMKNVLVGLGWDARSTDGQDFDLDASAFLLAANGKVRGDADFIFYNNLKSADGSVTHTGDNRTGEGDGDDESLKIKLDAVPGDVDKIIFVVTIHDAQARRQSFGQVSGAFIRLVNDDNQTEVARYDLTEDASTETAMLFGELYRHNGAWKFRAVGLGYAGGLASVCAQYGINAS
What is the function of this protein?
Not known; seems to contribute to the tellurium resistance (Ter) mechanism.
What are the official names of this protein?
Tellurium resistance protein TerD.
What is the protein family that this protein belongs to?
Belongs to the CAPAB/TerDEXZ family.
Protein: TM117_MOUSE
Sequence: MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYLITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPQTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRENTQVSVEDPLNDPALVCIRSDFNEIVYKSSHLTSENLSLHLKESTSEVEAEQEPAASQRMRTN
What is the function of this protein?
Involved in endoplasmic reticulum (ER) stress-induced cell death pathway.
What are the official names of this protein?
Transmembrane protein 117.
What is the protein family that this protein belongs to?
Belongs to the TMEM117 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNC_THEMA
Sequence: MNESERKIVEEFQKETGINFKNEELLFRALCHSSYANEQNQAGRKDVESNEKLEFLGDAVLELFVCEILYKKYPEAEVGDLARVKSAAASEEVLAMVSRKMNLGKFLFLGKGEEKTGGRDRDSILADAFEALLAAIYLDQGYEKIKELFEQEFEFYIEKIMKGEMLFDYKTALQEIVQSEHKVPPEYILVRTEKNDGDRIFVVEVRVNGKTIATGKGRTKKEAEKEAARIAYEKLLKERS
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_MYCA1
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLGARTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKREAIELAWTLLTGSVEQGGYGLDPERIWTTVYFDDDEAVRLWQEIAGLPAERIQRRGMEDNYWSMGIPGPCGPSSEIYYDRGEEFGVGGGPIANEDRYVELWNLVFMQSERGEGTSKTDFEILGPLPRKNIDTGMGVERVAFVLQGVHNVYETDLLRPVIDAVAARAPRPYDAGNHDDDVRYRIIADHSRTAAILIGDGVTPGNDGRGYVLRRLLRRVIRSARLLDIEGPIVGDLMATVRDAMGPSYPELVTDFDRIARIAVAEETAFNRTLAAGSKLFDEVASTTKATGAKSISGSDAFTLHDTYGFPIELTLEMASEAGLQVDEVGFRELMAEQRRRAKADAAARKHAHADLTAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVTHGGDGADRVELVLDRTPLYAESGGQIADEGTISGTGAGESARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPQWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRTQIEEVTNQAVQADFEVHTFTEQLEKAKAMGAIALFGESYPEQVRVVEIGGPFSLELCGGTHVHNSAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERMRLASARAAAGNAAAGAERIGNVRVVAQRMSGGMTAADLRSLVGDIRGKLGSDPAVVALIAEGEGGSVPYAVAANPAAQDLGIRANDLVKQLAAPVDGRGGGKADLAQGSGKDPAGIDAALDAVRSEIAAIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL1A1_CHICK
Sequence: MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEVAEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGGKLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFPLVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAAISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAAEFAHIGLFYHQGQCCIAGSRIFVEEPIYDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQKILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKTIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMSGNGRELGEYGLQEYTEVKTVTIKIPQKNS
What is the function of this protein?
Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid (By similarity).  Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid.  This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (By similarity).  Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic.  By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification.  Functions also downstream of fructosamine-3-kinase in the fructosamine degradation pathway by catalyzing the oxidation of 3-deoxyglucosone, the carbohydrate product of fructosamine 3-phosphate decomposition, which is itself a potent glycating agent that may react with lysine and arginine side-chains of proteins (By similarity).  Has also an aminobutyraldehyde dehydrogenase activity and is probably part of an alternative pathway for the biosynthesis of GABA/4-aminobutanoate in midbrain, thereby playing a role in GABAergic synaptic transmission (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase 1A1, 3-deoxyglucosone dehydrogenase, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, Retinal dehydrogenase 1, RALDH 1, RalDH1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, axon.
Protein: PQQD_GLUOX
Sequence: MTEAPHVVAEGTVLSFARGHRLQHDRVRDVWIVQAPEKAFVVEGAAPHILRLLDGKRSVGEIIQQLAIEFSAPREVIAKDVLALLSELTEKNVLHT
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.