PharMolix/UniProtQA huggingface dataset:
Protein: TRMFO_BARHE
Sequence: MFNKLSTPIHIIGGGLAGCEASWQIAQSGIPVILHEMRPQKKSEAHKTGQLAELVCSNSFRSDDSSTNAVGLLHTEMRLAKSLIMKAADANKVPAGSALAVDRDGFSKTVTAALENHPLITIKREEIQEIPENWPHIIIATGPLTSPKLAKAIQTITGTEALSFFDAIAPIIYTDSINMDICWYQSRYDKIGPEGTGKDYLNCPLNKEQYEAFVQALKNAEKTEFRDFEKTPYFDGCLPIEVMAERGLETLRHGPMKPMGLTNAHNPTVKAYAVVQLRQDNKLGTLYNMVGFQTKLKYGEQVRIFRMIPGLENAEFARLGGLHRNTYLNSPIILDQTLRLKQRPGLRFAGQITGCEGYVESSAIGLLAGRFAAAEYHYNCPCLPPLTTALGALLNHITGGHIVDEKTGRKSFQPMNINFGLFPPIASASYSGKRLPSKEKKLAKKQAITARALNTCIQWLINEEKNKL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_RHITR
Sequence: SAFRKLAMQFHPDKNPDDSNAERKFKEINEAYETLKDPQKRAAYDRYGHAAFEHGGMGGGGGFGAGFGGGGFSDIFEDIFGEMMGGGRARGRSSGGRERGADLRYNMEISLEEAFSGKTAQIRVPTSITCDVCSGSGAKPGTQPKTCGTCQGSGRVRAAQGFFSVERTCPTCHGRGQIIPDPCTKCHGQGRVTEERSLSVNIPAGIEDGTRIRLQGEGEAGLRGGPSGDLYIFLSVKPHEFFQRDGADLYCAVPISMTTAALGGTFDVATLDGTKSRVSVPEGTQVGKQFRLKGKGMPVLRSSQVGDLYIQIQIETPQKLTKRQRELLQEF
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT55_CONLT
Sequence: MRCLQVFIIFLLLIPSPPSVDAQRKTKDDVPLASFHDNAKRTLKRLWNKRSCCPREFLCCLR
What are the official names of this protein?
Conotoxin Lt5.5, Lt5e.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_CHLTR
Sequence: MFKCPERVSIKKKEDILDLPNLVEVQIKSYKQFLQIGKLAEERENIGLEEVFREIFPIKSYNEATILEYLSYNLGVPKYSPEECIRRGITYSVTLKVRFRLTDETGIKEEEVYMGTIPIMTDKGTFIINGAERVVVSQVHRSPGINFEQEKHSKGNVLFSFRIIPYRGSWLEAVFDINDLIYIHIDRKKRRRKILAMTFIRALGYSTDADIIEEFFSVEERSLRLEKDFVALVGKVLADNVVDADSSLVYGKAGEKLSTAMLKRILDAGVQSLKIAVGADENHPIIKMLAKDPTDSYEAALKDFYRRLRPGEPATLVNARSTIMRLFFDAKRYNLGRVGRYKLNKKLGFPLDDETLSQVTLRKEDVIGALKYLIRLRMGDEKTSIDDIDHLANRRVRSVGELIQNHCRSGLARMEKIVRERMNLFDFSSDTLTPGKIISAKGLVSVLKDFFSRSQLSQFMDQTNPVAELTHKRRLSALGPGGLNRERAGFEVRDVHASHYGRICPIETPEGPNIGLITSLSSFAKINEFGFIETPYRVVRDGIVTDEIEYMTADVEEECVIAQASAELDEYDMFKTPVCWARYKGEAFEADTSTVTHMDVSPKQLVSVVTGLIPFLEHDDANRALMGSNMQRQAVPLLKTEAAIVGTGLEGRAAKDSGAIIVAQEDGVVEYVDSYEIVVAKKNNPTLKDRYQLKKFLRSNSGTCINQTPLCSVGDVVTHGDVLADGPATDKGELALGKNVLVAFMPWYGYNFEDAIIISERLIKQDAYTSIYIEEFELTARDTKLGKEEITRDIPNVSEEVLANLGEDGVVRIGAEVKPGDILVGKITPKSETELAPEERLLRAIFGEKAADVKDASLTVPPGTEGVVMDVKVFSRKDRLSKSDDELVEEAVHLKDLQKEYKSQLAQLKVEHREKLGALLLNEKAPAAIIHRRSADILVQEGAIFDQETIELLERESLVDLLMAPCDMYDVLKDILSSYETAVQRLEVNYKTEAEHIKEGDADLDHGVIRQVKVYVASKRKLQVGDKMAGRHGNKGVVSKIVPEADMPFLANGETVQMILNPLGVPSRMNLGQVLETHLGYAAKTAGIYVKTPVFEGFPESRIWDMMIEQGLPEDGKSYLFDGKTGERFDSKVVVGYIYMLKLSHLIADKIHARSIGPYSLVTQQPLGGKAQMGGQRFGEMEVWALEAYGVAHMLQEILTVKSDDVSGRTRIYESIVKGENLLRSGTPESFNVLIKEMQGLGLDVRPMVVDA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: AROA_YERP3
Sequence: MLESLTLQPIALVNGTVNLPGSKSVSNRALLLAALAEGTTQLNNVLDSDDIRHMLNALQALGVNFRLSADRTCCEVDGLGGKLVAEQPLSLFLGNAGTAMRPLAAVLCLGNSDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFRGGELTVDGRVSSQFLTALLMTAPLAEQDTTIRIMGDLVSKPYIDITLHLMKAFGIDVGHENYQIFHIKGGQTYRSPGTYLVEGDASSASYFLAAAAIKGGTVRVTGIGKKSVQGDTKFADVLEKMGAKVTWGDDYIECSRGELQGIDMDMNHIPDAAMTIATTALFATGPTTIRNIYNWRVKETDRLTAMATELRKVGAEVEEGEDYIRVVPPVQLTAADIGTYDDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQFARLSQLA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_PSEPF
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNGCGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS2_SALAI
Sequence: MAVVTMRQLLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLRQTLDYIEKAYDFVRGTVAEGGSILFVGTKKQAQEAIAEQATRVGQPYVNHRWLGGMLTNFQTVYKRLQRMKELEALGDLSGTAAGYTKKETLQLSREKEKLSRTLGGLRDMQKLPAAIWVVDTKKEHIAVDEARKLGIPVIAVLDTNCDPDEVDYPIPGNDDAIRSAELLTKVVAAAVADGLIARSGRRRGTDEKPEAGVASDEPLAEWERELLEEPKKSDEPKSDEQPAAAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RNH2_STAES
Sequence: MSLTIKEIKEKLSRIETLEELHKHEANNDSRKGVINAIKSREKNILKQQALEEHYLSMNQYENNIMSSNRDALICGIDEVGRGPLAGPVVACAVILEKNHHYIGLDDSKKVSPKNRARLNQNLKENVYQYAYGIASSVEIDELNIYRATQLAMLRAINQLDVTPTHLLIDAMTLDIDIPQTSIIKGDAKSVSIAAASIMAKEYRDQYMRQLSKQFPEYGFDKNAGYGTKQHLKAIDQVGIINEHRQSFEPIKSMMK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1651_HAEIN
Sequence: MDGILRKLISIKDLHHCLQKFFVDERESIIEMNDNKLSEQFDLALIETHGKSKILKNLSLFKQTMSNYLTQLSKDNMKETENTVHKIKRVAA
What are the official names of this protein?
Uncharacterized protein HI_1651.
Protein: MACA_ECOLI
Sequence: MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTKAVSQQDLDTAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSAMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacA stimulates the ATPase activity of MacB by promoting the closed ATP-bound state of MacB, increases the capacity of MacB to bind macrolides such as erythromycin, and provides a physical link between MacB and TolC.  When overexpressed, the system confers resistance against macrolides composed of 14- and 15-membered lactones but no or weak resistance against 16-membered ones.  In addition, MacA binds tightly rough-core lipopolysaccharide (R-LPS), suggesting that the system could also transport R-LPS or a similar glycolipid.
What are the official names of this protein?
Macrolide export protein MacA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: IMB5_YEAST
Sequence: MDINELIIGAQSADKHTREVAETQLLQWCDSDASQVFKALANVALQHEASLESRQFALLSLRKLITMYWSPGFESYRSTSNVEIDVKDFIREVLLKLCLNDNENTKIKNGASYCIVQISAVDFPDQWPQLLTVIYDAISHQHSLNAMSLLNEIYDDVVSEEMFFEGGIGLATMEIVFKVLNTETSTLIAKIAALKLLKACLLQMSSHNEYDEASRKSFVSQCLATSLQILGQLLTLNFGNVDVISQLKFKSIIYENLVFIKNDFSRKHFSSELQKQFKIMAIQDLENVTHINANVETTESEPLLETVHDCSIYIVEFLTSVCTLQFSVEEMNKIITSLTILCQLSSETREIWTSDFNTFVSKETGLAASYNVRDQANEFFTSLPNPQLSLIFKVVSNDIEHSTCNYSTLESLLYLLQCILLNDDEITGENIDQSLQILIKTLENILVSQEIPELILARAILTIPRVLDKFIDALPDIKPLTSAFLAKSLNLALKSDKELIKSATLIAFTYYCYFAELDSVLGPEVCSETQEKVIRIINQVSSDAEEDTNGALMEVLSQVISYNPKEPHSRKEILQAEFHLVFTISSEDPANVQVVVQSQECLEKLLDNINMDNYKNYIELCLPSFINVLDSNNANNYRYSPLLSLVLEFITVFLKKKPNDGFLPDEINQYLFEPLAKVLAFSTEDETLQLATEAFSYLIFNTDTRAMEPRLMDIMKVLERLLSLEVSDSAAMNVGPLVVAIFTRFSKEIQPLIGRILEAVVVRLIKTQNISTEQNLLSVLCFLTCNDPKQTVDFLSSFQIDNTDALTLVMRKWIEAFEVIRGEKRIKENIVALSNLFFLNDKRLQKVVVNGNLIPYEGDLIITRSMAKKMPDRYVQVPLYTKIIKLFVSELSFQSKQPNPEQLITSDIKQEVVNANKDDDNDDWEDVDDVLDYDKLKEYIDDDVDEEADDDSDDITGLMDVKESVVQLLVRFFKEVASKDVSGFHCIYETLSDSERKVLSEALL
What is the function of this protein?
Required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.  Serves a receptor for nuclear localization signals.  Mediates the nuclear import of TATA-binding protein (TBP) and of histones H2A and H2B.
What are the official names of this protein?
Importin subunit beta-5, 114 kDa karyopherin, Karyopherin subunit beta-5, Karyopherin-114.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex.
Protein: RIMK2_SHESM
Sequence: MRIAILSQGPELYSTKRLVEAATLRGHEVKVINPLECYMNINMRQSSIHIGGEELPPFDAVIPRIGASITFYGSAVLRQFEMMGVYALNDSVGISRSRDKLRSMQLMSRRGIGLPITGFANKPSDIPDLIDMVGGAPLVIKLLEGTQGIGVVLAETRKAAESVIEAFMGLKANIMVQEYIKEANGADIRCFVLGDKVIAAMKRQAMPGEFRSNLHRGGTASLVKLTPEERSVAIRAAKTMGLNVAGVDLLRSNHGPVVMEVNSSPGLEGIEGATAKDVAGAIIEFVEKNALKAKKPTQA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: MNME_RUEPO
Sequence: MDTIFALATAQGKAGVAVIRLSGPRAYHTACLLAGPDLPSRGLSVRQLKDSQGARLDDGVVLTFAAPASFTGEDVAEFQIHGSLATTEAVLRCLGDLDGLRLAEPGEFTRRALENGKMSLPQVEGLADLIDAETEAQRKQAQAVLNGALGQLAEGWRAKLIRAAALLEAVIDFADEEVPTDVSPEVRALLAEVRADLEHEIAGVRIAERIRTGFEVAIIGPPNAGKSTLLNMLAGREAALTSEVAGTTRDVIEVRMDLGGLPVTLLDTAGLRETGDLVEGMGIALARRRADQADLRVFLTEDVDAMGVELQPDDLHVLPKADQRPDTANAISGVTGQGVDQLVQRISDVLKTRSSSAGIATRERHRVAMKTALDALDRTGTVLESGPDLYDIAAEELRTAIRALESLVGRIGVETLLDEIFASFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QSER1_HUMAN
Sequence: MNFLSTAESRTAQAAASGTTLLPQFRAPSWQTGMHSSAATELFATGPLPSTGTLPPSLSAYQHPTTFSNRNFATTSPLVLQDSTFNTTSNGILSHHDPLLQIKTSQGTVPTALAFERLGSSVLSNSIPPQSSTYRSAQESAPHLLQPQFSLLPSALGGSQQTPQAYSSTLFTSSTASIERALLRECSVIKHHQRPSGTQSIQAQLTGSQHSLHSYLSNSSVVNFQETTRQSSLSCSPIGDSTQVSNGGLQQKTSQVSVELAQSYSSAIPSSGYPPSTTKIKSCSTEQPLTSTKTPKPQSIIPPVQTLSYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSKVEKLPPLYKTLTFSGSSQTVTPENQTLNYSSNQQEVLSSVTNENYPAQTRDLSSVSQSQSYSSGHSQGLSPVSQTQVSYSSQSQVLSVVSLSESYASGESLTLTAPSLSYSSASRAQNLPDSSPTQNYISMHSSQNVQTQESSSPQSQKFLPAVQSSSFASSTHCQTLQNNITSPDPKSYAERKLDSDVYPSSKQEDGFPMQELQVLQPQASLESSTQRLSDGEINAQESTYKVSKADDRYSQSVIRSNSRLEDQVIGVALQASKKEESVVGSVTQLNQQIGQVNNAATLDLKNSTNLIQTPQIRLNTKDLKQQHPLILKVHESKVQEQHDQIINASSQIQIPNHALGHGHQASLPNTQVLLDSACDLQILQQSILQAGLGQVKASLQAQRVQSPQQIVHPFLQMEGHVIQSNGDHSQQQLHPQNSEVMKMDLSESSKPLQQHLTTKGHFSETNQHDSKNQFVSLGSMCFPEAVLLSDERNILSNVDDILAATAAACGVTPTDFSKSTSNETMQAVEDGDSKSHFQQSLDVRHVTSDFNSMTATVGKPQNINDTSLNGNQVTVNLSPVPALQSKMTLDQQHIETPGQNIPTKVTSAVVGPSHEVQEQSSGPFKKQSATNLESEEDSEAPVDSTLNNNRNQEFVSSSRSISGENATSESEFTLGGDDSGVSMNPARSALALLAMAQSGDAVSVKIEEENQDLMHFNLQKKRAKGKGQVKEEDNSNQKQLKRPAQGKRQNPRGTDIYLPYTPPSSESCHDGYQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPKQQFSTLAVRMPNRTRRPGTQMVRTFCPPPLPKPSSTTPTPLVSETGGNSPSDKVDNELKNLEHLSSFSSDEDDPGYSQDAYKSVSTPLTTLDATSDKKKKTEALQVATTSPTANTTGTATTSSTTVGAVKQEPLHSTSYAVNILENISSSESSKPIELDGLPSDQFAKGQDTVAIEGFTDEEDTESGGEGQYRERDEFVVKIEDIETFKEALKTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKSKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRTVQAKPSSSSKTSDPLASKTTTTKAPSVKPKVKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEIHTSSSDDEEFEPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLLNLHLDQSFKNALESFPELTIITRDSKAKSGGTAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKDEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS
What is the function of this protein?
Plays an essential role in the protection and maintenance of transcriptional and developmental programs.  Protects many bivalent promoters and poised enhancers from hypermethylation, showing a marked preference for these regulatory elements over other types of promoters or enhancers.  Mechanistically, cooperates with TET1 and binds to DNA in a common complex to inhibit the binding of DNMT3A/3B and therefore de novo methylation.
What are the official names of this protein?
Glutamine and serine-rich protein 1.
What are the subcellular locations of this protein?
Chromosome.
Protein: PYRDA_STRE4
Sequence: MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVTKTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVVGMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTKPLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGIGGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQEGPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Putative dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_NOSP7
Sequence: MTNEKMIFRNRVVDKGQLRNLISWAFTNYGTARTAVMADKLKDLGFRYATKAGVSISVDDLMIPPTKRLLLEAAEEEIRATETRYQRGEITEVERFQKVIDTWNGTSEALKDEVVVHFKKTNPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIREFDCGTTRGLTIGPMTEGAKTLIPLATRLMGRVIGEDVVHPVTKELIAARNSPIPEDLAKKIEKSGVGEVVVRSPLTCEAARSVCQHCYGWSLAHAKMVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVAQQVRSKIDGTVKLPRKLKTRTYRTRHGEDALYVEANGIMLLEPTKVGDVTPENQEVHLTQGSTLYVFDGNKVKQGQLLAEVALGGRTTRTNTEKAVKDVASDLAGEVQFAEVVPEQKTDRQGNTTTTAARGGLIWILSGEVYNLPPGAELVVKNGDAIAANGVLAETKLASLHGGVVRLPEATPGKSTREIEIITASVVLDQATVTVQSSQGRNNYLVSTGNNQVFNLRATPGTKVQNGQVVAELIDDRYRTTTGGFLKFAGVEVQKKGKAKLGYEVVQGGTLLWIPEESHEVNKDISLLLVEDGQFVEAGTEVVKDIFCQNSGVVEVTQKNDILREVVVKPGELLMVDDPESVIGRDNTFIQPGEEFQGNVATELRYIQYVETPEGPALLSRPVVEFAVPDNPDVPSTTSVSQQTGRSIQLRAVQRLPYKDSERVKSVEGVELLRTQLVLEIEQEGEQDHNASPLAADIELVEDTENPEVQRLQLVILESLVIRRDITADATQGSTQTTLEVYDGLTIAPGSVVARTQILCKEGGEVRGVRKGTENVRRCLVLRDVDRLTINTSTQPKVKVGDLLVEGTEVAPGVFAPESGQVVDIKNAAAASGGESALSTKNYVITTRIGRPYRVSPGAVLQIEDGDLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEACILCRRGGEVKVVYAESGDEAIAIKVVESNGVVTDYPLGPGQNLIVPDGSIVLAGQPLTDGPSNPHEILEIFFSLGSEDGIYACASLALQKVQTFLVNEVQMVYQSQGIDISDKHIEVIVRQMTNKVRIDDGGDTTMLPGELVELRQVEQVNEAMAITGGARAQYTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGYNTYEEPGAIDDYAAEISSSVLDEVDDPLDMVLDDRTARTYNLDSPTLGESGFGSRRAERSVLDDEDELIADEVVDDDDFEEEEEDDEDDFDDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: XPO1_SCHPO
Sequence: MEGILAFDRELDVALLDRVVQTFYQGVGAEQQQAQQVLTQFQAHPDAWSQAYSILEKSEYPQTKYIALSVLDKLITTRWKMLPKEQRLGIRNYIVAVMIKNSSDETVLQQQKTFLNKLDLTLVQILKQEWPHNWPNFIPEIVQASKTNLSLCENNMIVLRLLSEEIFDYSAEQMTQLKTKNLKNQMCGEFAEIFQLCSQILERAQKPSLIKATLGTLLRFLNWIPLGYIFETNIVELITNRFLNVPDFRNVTIECLTEIASLTSQPQYNDKFVTMFNLVMTSVNSMLPLQTDFREAYEESSTNEQDFIQNLALFLCAFFSSHLRPLENPENQEVLLNAHSYLLNISRINEREIFKICLEYWSKLVAQLYEEMQQIPMSEMNPLLNLSSPTSLISSNPNMLANLPLRKHIYKDILSTLRLVMIENMVKPEEVLIVENDEGEIVREFVKETDTITLYKSMREVLVYLTHLDVVDTEIVMTEKLARIVVGTEWSWQNLNTLCWAIGSISGAMNEEMEKRFLVNVIKDLLGLCEMKRGKDNKAVVASNIMYVVGQYPRFLKAHWKFLKTVVNKLFEFMHEYHEGVQDMACDTFIKIAQKCRRHFVAQQLGETEPFINEIIRNLAKTTEDLTPQQTHTFYEACGYMISAQPQKHLQERLIFDLMALPNQAWENIVAQAAQNAQVLGDPQTVKILANVLKTNVAACTSIGSGFYPQIAKNYVDMLGLYKAVSGLISEVVAAQGNIATKTPHVRGLRTIKKEILKLVDAYISRAEDLELVGNTLIPALFEAVLLDYLQNVPDARDAEVLNLITTIVNQLSELLTDKIPLVLDAVFGCTLEMISKDFSEYPEHRAAFFQLLRAINLNCFPALLNIPAPQFKLVINSIVWSFKHVSRDIQETGLNILLELINNMASMGPDVSNAFFQTYYISLLQDILYVLTDSDHKSGFKLQSLILARLFYLVESNQITVPLYDPSQFPQEMNNQLFLRQYIMNLLVTAFPHLQPIQIQEFVQTVLALNQDSIKFKLALRDFLIQLKEFGGDNAELYLEEKEQELAAQQKAQLEKAMTVPGMIKPVDMPTMEEEEL
What is the function of this protein?
Receptor for the leucine-rich nuclear export signal (NES).
What are the official names of this protein?
Exportin-1, Caffeine resistance protein 2, Chromosome region maintenance protein 1.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized in the nucleus and at its periphery.
Protein: 2ABD_RAT
Sequence: MAGAGGGGCPTGGNDFQWCFSQVKGAVDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKGRAHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHAKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMEGRPVETHHVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRNTRRDVTLEASRENSKPRASLKPRKVCSGGKRKKDEISVDSLDFNKKILHTAWHPMESIIAVAATNNLYIFQDKIN
What is the function of this protein?
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit.  The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis.  During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors.  Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform, PP2A subunit B isoform B55-delta, PP2A subunit B isoform PR55-delta, PP2A subunit B isoform R2-delta, PP2A subunit B isoform delta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_IDILO
Sequence: MICGTDEAGRGPIAGPVVAAAVILDPDNPIEGLNDSKKLSEKKREKLSLEIKEKALYWAIAQSDPDEIEAINILWASMKAMQRAVEALPVKPDMVLVDGNRVPELKVPAKAIVGGDASEQCIAAASILAKVERDRQMLKWHELYPQYEFDKHKAYGTPKHLELLEKHGPCPIHRKGFNPVKRLLANL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CK5P1_ORYSJ
Sequence: MAAPLTAAAALRLGRGLSHRRAFLLRRRYSPAPLAPSPCAAPRCLSSAAHPPPPPPRRLARSGPSRPLAASAATAVSEAQTDLESGPVTASKGRIYHETYGCQMNVNDMEIVLSIMKNEGYDEIVPDPESAEIIFINTCAIRDNAEQKVWQRLNYFWFLKRQWKANVAAGRSRSLRPPKIAVLGCMAERLKEKILDSDKMVDVVCGPDAYRDLPRLLQEVDYGQKGINTLLSLEETYADITPVRISDNSVTAFVSIMRGCNNMCSFCIVPFTRGRERSRPVSSIVREVGELWKAGVKEVMLLGQNVNSYNDTSEVEELEPGKNWELSEGFSSMCKVKNMGLRFADLLDQLSLEYPEMRFRFTSPHPKDYPDELLYLMRDRHNVCKLIHMPAQSGSSAVLERMRRGYTREAYLELVQKIRSIIPDVGLSSDFISGFCGETEEEHAETLTLVRAVGYDMAYMFAYSMREKTHAHRNYVDDVPDDVKQRRLAELISTFRETTAKIYDSQVGTVQLVLVEGPNKRAPETEMIGKTDRGHRVSFASVPVPHTFEGDELRKPVVGDFIEVKITKSSTASLSGDVIARTSLSKFYKNHSSEAHAVAA
What is the function of this protein?
Potential regulator of CDK5 activity.
What are the official names of this protein?
CDK5RAP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
Protein: PEPQ_ERWT9
Sequence: MESLVTLYQEHIKTLQQRAQQVLARHSLDAMLIHSGELLTVFLDDHTYPFKVNPQFKAWVPVTQVPNCWLWIDGVNKPKLWFYSPVDYWHDVEPLPQSFWTGEIDIVPLKNADDIARLLPTQRQNVAYIGPVPARATQLGFNTEAINPPGVIDFLHYHRAYKTGYELYCLRQAQVIAVTGHRAAKEAFKSRLSEFDINVAYLSATGHRDTDVPYGNIIALNEHAAVLHYTKLDQQPPEKRRSFLIDAGAEYQGYAADLTRSYAASEGSDYAQLIKDMNKEELELIATMKTGVRYTEYHQQMHYRIASLLLKHQLVNGLTAEAMVKENLTGPFMPHGIGHSLGLQVHDVAGFMQDDRGTHLAAPQQYPYLRCTRVLEPGMVLTIEPGIYFIDSLLAPWRAGKFSQYFDWAKIDELKAYGGIRIEDNVVIHKNSVENMTRDLHLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: LHX5_XENLA
Sequence: MMAHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKTDFFRRFGTKCAGCSLGISPSDLVRKARNKVFHLNCFTCMVCNKQLSTGEELYIIDENKFVCKEDYISASSLKESSLNSVSSCTDRSLSPDIQDPIQDESKETDHSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFIATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEILSSGPYSYYGDYQGDYYGSGNYDFFPHGPPSSQTQSPADSSYLQNSGPGSTPLGPLESQLSGHHPSENQRYVDMISHPDTPSPEPGMTGPLHPISGEVFTGGPSPPFSMSNNSGFSGPLPHQNLDINEATVW
What is the function of this protein?
Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon.
What are the official names of this protein?
LIM/homeobox protein Lhx5, LIM homeobox protein 5, Homeobox protein LIM-5, xLIM-5, xLIM-2A.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y147_ANADE
Sequence: MTATVSHAGPQVVILTGVSGSGKSTALRALEDAGFYCVDNLPIVFLEKLLELSGHTAGEVSRMALVVDAREGRFLVEAPRVIRELRQKGADVEVLFLDASDEALVRRYSETRRRHPLAGEGGTVPDGIAAERLALADVRGIADEVIDTTTLNVHELKRLVTRRFVAGDGAKLGVTLVSFGFRFGIPTHADLVLDVRFLPNPFFVPELKPHPGTDPRVAEFVLGQADAKAFLERLVDLLGFLLPRYRNEGKSYLTIAIGCTGGKHRSVALAAALAERLEGSGQPVRLWHRDVEKE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Adeh_0147.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PYRE_NEIMF
Sequence: MTDFRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGLSTLQLAKFYAQSIIESGIRFDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAKDHGEGGVLVGAPLKGRVLIIDDVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGTGELSAVQEVEKQYGLPVAPIASLNDLFILLQNNPEFGQFLEPVRAYRRQYGVE
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.