PharMolix/UniProtQA huggingface dataset:
Protein: MURJ_VIBCH
Sequence: MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHASGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVALSGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGVVKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHTMDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTPSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRYGIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLAMAGAVMTGALLWQLDTMATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL19_PSESM
Sequence: MTNKIILALEAEQMTKEIPTFAPGDTIVVQVKVKEGDRARLQAFEGVVIAKRNRGVNSAFTVRKISNGVGVERTFQTYSPQIDSMAVKRRGDVRKAKLYYLRDLSGKAARIKEKLS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DNLJ_BACSU
Sequence: MDKETAKQRAEELRRTINKYSYEYYTLDEPSVPDAEYDRLMQELIAIEEEHPDLRTPDSPTQRVGGAVLEAFQKVTHGTPMLSLGNAFNADDLRDFDRRVRQSVGDDVAYNVELKIDGLAVSLRYEDGYFVRGATRGDGTTGEDITENLKTIRNIPLKMNRELSIEVRGEAYMPKRSFEALNEERIKNEEEPFANPRNAAAGSLRQLDPKIAAKRNLDIFVYSIAELDEMGVETQSQGLDFLDELGFKTNQERKKCGSIEEVITLIDELQAKRADLPYEIDGIVIKVDSLDQQEELGFTAKSPRWAIAYKFPAEEVVTKLLDIELNVGRTGVITPTAILEPVKVAGTTVSRASLHNEDLIKEKDIRILDKVVVKKAGDIIPEVVNVLVDQRTGEEKEFSMPTECPECGSELVRIEGEVALRCINPECPAQIREGLIHFVSRNAMNIDGLGERVITQLFEENLVRNVADLYKLTKERVIQLERMGEKSTENLISSIQKSKENSLERLLFGLGIRFIGSKAAKTLAMHFESLENLKKASKEELLAVDEIGEKMADAVITYFHKEEMLELLNELQELGVNTLYKGPKKVKAEDSDSYFAGKTIVLTGKLEELSRNEAKAQIEALGGKLTGSVSKNTDLVIAGEAAGSKLTKAQELNIEVWNEEQLMGELKK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: XPT_PSEPG
Sequence: MEALHQKIREEGIVLSDQVLKVDAFLNHQIDPALMQLIGDEFARLFADAGVTKIVTIEASGIAPAVMTGLKLGVPVIFARKHQSLTLTENLLTASVYSFTKQTENTVAISPRHLNSSDRVLVIDDFLANGKASQALISIIKQAGATVAGLGIVIEKSFQGGRAELDSQGYRVESLARVKSLEGGVVSFIE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIC9_YEAST
Sequence: MRLIFIAKMLQYSFLPFSPFNLLNFDNSISVSWFITYSVIVSIWGFAVWIEGAYRNKINLQLPRCTKIKCSRYNTRIKSPKWFNCKNWMHFFLLYLFLTASNLIVQLAYFSKEMCSQGINVPGTKKPGNRVYLSVIILMGNG
What are the official names of this protein?
Uncharacterized protein YIL029C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYSI_NEIMF
Sequence: MTVQTKTKGLAWQEKPLSDNERLKTESNFLRGTILDDLKDPLTGGFKGDNFQLIRFHGMYEQDDRDIRAERAEAKLEPLKFMLLRCRLPGGIIKPSQWIELDKFARENSHYRSIRLTNRQTFQFHGVPKAKLQTMHRLLHKLGLDSIATAADMNRNVLCTSNPIESELHRQAYEYAKKISEHLLPRTRGYLDVWVDGKKVQSSDDFLQEDEPILGKTYLPRKFKTAVVIPPLNDVDCYGNDLDFVAVSDGNGQLAGFNVLAGGGLSMEHGNTKTYPNISLELGFVPPEHALKAAEAVVTTQRDFGNRSDRKNARTRYTIQNMGLDNFRAEVERRMGMPFEPIRPFKFTGRGDRIGWVKGIDGNWHLTLFIESGRLVDEGGKQLLTGVLEIAKIHKGDFRITANQNLIVANVAEADKAKIEELARTYGLIRNDVSKLRENAMSCVSFPTCPLAMAEAERVLPDFIGELDKIMAKHGTSDDYIVTRITGCPNGCGRAMLAEIGLVGKAVGRYNLHIGGDREGVRIPRLYKENITLPEILSELDDLIGKWAAGRDTDEGFGDFAIRTGIVKPVLDAPVDFWDASKAVPIARA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: P5CR_SCHPO
Sequence: MSGFCVLGCGTMGKALLTGIFDSIAENGNDVSDEIIIPNKFYACVKFPKEKEDVQKLFGDRVKVVMGAKENAEMAAISNVLLLSCKPQAAEDVLNSPKMKEALKGKLILSILAGKTISSLQSMLDESTRVIRIMPNTASRIRESMSVICPGPNATEEDIKFAEWVFNGIGRSMKLPEKLIDAATAVCGSGPAFVATMIEAMTDGGVMMGIPFPQAQELAAQTMVGTGRMVLQGQHPAMIRNDVSTPAGCTISGLLALEDGKIRSTIARGIEQATKTASGLGK
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
Protein: RBSD_PSEF5
Sequence: MKKTPLLNIALSRLIASLGHGDIVVIGDAGLPVPPGVELIDLALTHGVPDFLTTLKVLLSEMQVERHVLAEEILLKQPTPLAALEGMTAGGELGQRQLMNHEDFKVLSRQARAVIRTGECQPYCNIALIAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDLA_ECOLI
Sequence: MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVDGVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQLTLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGELDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLASVHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTEHQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRDMYRYQQLEAALDDAPENREEAVDA
What are the official names of this protein?
Multidrug resistance-like ATP-binding protein MdlA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SN_HUMAN
Sequence: MGFLPKLLLLASFFPAGQASWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITAIWYYDYSGQRQVVSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEISEVNRWSDVKGTLVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQEQVRLQWQGQDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRILRCQLSVANHRAQSEIHLQVKYAPKGVKILLSPSGRNILPGELVTLTCQVNSSYPAVSSIKWLKDGVRLQTKTGVLHLPQAAWSDAGVYTCQAENGVGSLVSPPISLHIFMAEVQVSPAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLLEDAHSHTLRLHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATSTLDFHANAARLLISPAAEVVEGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSSLLLPAASSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAAGAGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLRVEIHNPLLEEEGLYLCEASNALGNASTSATFNGQATVLAIAPSHTLQEGTEANLTCNVSREAAGSPANFSWFRNGVLWAQGPLETVTLLPVARTDAALYACRILTEAGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLLATSLGPQVPSHGRFQAKAEANSLKLEVRELGLGDSGSYRCEATNVLGSSNTSLFFQVRGAWVQVSPSPELQEGQAVVLSCQVHTGVPEGTSYRWYRDGQPLQESTSATLRFAAITLTQAGAYHCQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGPGRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTLRLEIHGAMLEDEGVYICEASNTLGQASASADFDAQAVNVQVWPGATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAHSIPLPNVTVRDATSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRVILAPEAAVPEGAPITVTCADPAAHAPTLYTWYHNGRWLQEGPAASLSFLVATRAHAGAYSCQAQDAQGTRSSRPAALQVLYAPQDAVLSSFRDSRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDVPAGDDTYVCTAQNLLGSISTIGRLQVEGARVVAEPGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQAGMYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLGSASTSTYFGVRALHRLHQFQQLLWVLGLLVGLLLLLLGLGACYTWRRRRVCKQSMGENSVEMAFQKETTQLIDPDAATCETSTCAPPLG
What is the function of this protein?
(Microbial infection) Facilitates viral cytoplasmic entry into activated dendritic cells via recognition of sialylated gangliosides pesent on viral membrane.
What are the official names of this protein?
Sialoadhesin, Sialic acid-binding Ig-like lectin 1, Siglec-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: EFTS_STRTD
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVEVDGDIEKAIELLREKGMAKAAKKADRIAAEGLTGIYVSGNVAAVVEVNAETDFVAKNAQFVELVNETAKVIAEGKPANNEEALALTMPSGETLEAAYVTATATIGEKISLRRFAVVEKTDAQHFGAYQHNGGRIGVVSVIEGGDEAIAKQISMHIAAMKPTVLSYSELDEQFVKDELAQLNHAIDQDNESRAMVNKPALPHLKYGSKAQLTDEVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRFILDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFVRFEVGEGIEKASNDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH36_DANRE
Sequence: MEIGKQTRLSRPHRLSESSKVYRWADQANNLLQGLNEQRQHGQMCDVVLVADDQRIPAHRALLAVSSPYFQAMFTLGMREEHESEIELVGASYVGVKAVIDFLYSGNLPLDGGNIDYVLETAHLLQVWQAVDFCCQYLEKEVREDNYLYLQELALLYSLDRLDAFIDRFILKHFSTLAITSEFLQDVRMFKLCAYLSSEQVQCLNEETLFEVAFKWLKQKPERLEFALQLLSNIRFALIPFYLLKYYVLPNLHSLLPLDTSCKVLVEEAIDYHRKLSAQPVMQTQRTGLRGGVECLLLLGGEVSERGEGLSAEVCWLDEEAGKWVEETKMPAPRSQHCVAVLGGFIFTAGGSCSPDNGGDSASDMLYRYDPRRCHWIKGAPMNQRRVDFYLGTMGECLIAVGGRNDSGPLSSVEVYHPADDHWTYVAELPKFTYGHAGTIHKGIVYISGGHDYQIGPYRHDMLSYDPKTADAWNECQAMILARGWHSMASLEDRIYAIGGSDDHEDSMERFDVLEVEAFDPQTNQWTMIAPLRYASSEAGLAVLNRKIYVLGGYSWETMDFSQGTQVFDPDKEQWTLGPNLPKHIAGPSCVCLIEPELIDSIDTE
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Kelch-like protein 36.
Protein: RRF_COXB2
Sequence: MINDIINDSKSRMEKSLGSLKTELAKLRTGRAHPSLLEHIKVDYYNVETPLSQVASIAIENPRTLSITPWEKNMVGPIEKAIQKADLGLNPATVGMVIRVPLPPLTEERRKELARVVREEAEHARVAIRNIRREANNDLKELMKEKEISEDEERRAQTAIQKLTDAQIAEVDKMASQKEADLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_LACLA
Sequence: MFARILGLDVGTKTVGVSVSDLLGMTAQPVETIKIDSEAGELGFERLGVLIKEYKPEKVVLGLPKHMNGDEGIRAEASRDYGTKLANEFGLEVAYQDERLTTAQAEKVLIDGGVRRKERKKSIDKLAAVLILQNYLDAHALKL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAC1_PRUPE
Sequence: MKIFNWVHKRLHQRVVKDGFAGNVKKSELETNDKDTQAFLKQVGLVNVDGLDGWRDGILTIGTFGFDPLKPSTHQNEYFVLESEEDDQESHGFSHSGNDDDDDDDEHYDHSVEDEELNPLMFTTFEHSFEDIGSNFDAIVQKPADVILTVDGVPLTPFEGSSEISTKPDQSANDQSKNKKGQRITLADLFQADVPDVGQLKLDSGKVQPEMEKKMNARTRSGLAFAKKLIPRVKDDSSPIKNMQRLMRRMLKRKIHPAELEVKIHKSDGQKQPSAVELISNVENDAYESVSLLPIQGAPCVH
What is the function of this protein?
Involved in the regulation of axillary shoot growth angle (PubMed:23663106).  Promotes horizontal shoot growth (PubMed:23663106).
What are the official names of this protein?
Protein TILLER ANGLE CONTROL 1, PpeTAC1.
What is the protein family that this protein belongs to?
Belongs to the TAC family.
Protein: RHLB_SHESM
Sequence: MSQTHLSNQKFADLPLHPEVKQALAENGFEFCTPIQALSLPVLLQSKDIAGQAQTGTGKTMAFLVATFNHLLSTPIPENRQLNQPRAIIMAPTRELAIQIAKDAILLAKHTHLKVGIVYGGESYDVQRKVLDQGVDILIGTTGRIIDYVRQGIISLNAIQAVVLDEADRMFDLGFIKDIRFLFRRMPNADQRLNMLFSATLSMKVQELAYDHMNDPVKVEIAPEEKTSKNIKEEIFYPSQEDKIRLLLTLIEEDWPEKAIVFSNTKHSCENLWSWLEGDGHRVGLLTGDVPQKKRIRILEQFTQGQLDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGNKGVSVSFACEEYALNLPAIESYINHSIPVSNYDRDALLDDIPPPVKIHRKHPAGARNLRERSGAGRPQGAHRSGGRPPRHDRTRRQP
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPC6_CAEEL
Sequence: MGYVGNVSYPDTIPGQGNLVFEASFESGNLGRVDKVSCSEYDLFIRPDTLNNKYRVWFYFECKNASENQRAIFNIVNFSKQRTLFEMGIAAPVVKSNAQNSWARIPSRHIYYYRSSQHNDRWILSFAFIFESPDPVQFAYCIPYTYGQMQIWLNELESRKYPFFHRDLLVQTVQKRRVDLITIDATPDTFQGSKKMIFLTARVHPGESPSSHVMHGIIEFLVSKDDRAQKLRKVYCFKIIPMLNPDGVFLGNYRCSLMGHDLNRMWRTPSDWAHPSIYAVKNLLTQYDNNPQAQTVIYVDLHAHSQKPNCFLYGNVNMSAVEEKSTFRQLWLPHLLADLSEDYSLEFTQFNTDVEKAGTGRRTMGDLLSCLCYTLEVSFFSYRHTDSSGNGIQHCTPYLQYKYEALGEAFCRALLNFYEADCGLREIVLERPFKTFLPARAQKTLKKQARKVIQTVMMK
What is the function of this protein?
Metallocarboxypeptidase that catalyzes the removing of polyglutamate side chains that are present on the gamma-carboxyl group of glutamate residues of tubulin in sensory cilia (PubMed:17244817, PubMed:20519502).  Probably via the deglutamylation of tubulin, promotes microtubule stability required for axon regrowth after injury (PubMed:23000142).  Also regulates microtubule dynamics in uterine muscle cells (PubMed:24780738).
What are the official names of this protein?
Cytosolic carboxypeptidase 6, ATP/GTP-binding protein-like 4 homolog, CeAGBL4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_CHLMU
Sequence: MHENFDKRLELLLEGLSLTRRFLFDPEEKETELKNLEQLSIQDSFWDDVSRAGRISEKIARLKQQLLEYNELKNKINSIKFFLEDEESSKDLEIQKELEKEFIFCEKKIAEWETLRLLAGELDRNSCFLSINAGAGGTESCDWVEMLFRMYSRWANSHGWKVEVIDRLDGEVAGIKHITLKLIGEYAYGYAKAESGVHRLVRISPFDSNAKRHTSFASVEVFPEIDDKIEVEIRPGDIRIDTYRSSGAGGQHVNVTDSAVRITHFPTGIVVSCQSERSQIQNREACMNMLRARIYQKLLQERLEKQNTNRKEKKEISWGSQIRNYVFQPYTLVKDVRTGYEVGNIQAMMDGELLDAFIKAYLADYGEIT
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_RICPR
Sequence: MSRVGKLPITIPEGVKVGLNDLEVKISGPKGELSKTFKGNIAIIMEENKLVVKPLAVNKNARAMWGTARSIICNMITGVKEGFKLKLEINGVGYRAMVKGKYLNLMLAKSHNTKIEIPSNIKIDLPKQNIILLEGIDKEKLGQFASIIIKQRPPEPYKGKGIKFENKFIQRKEGKKN
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PECR_HUMAN
Sequence: MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEKAKL
What is the function of this protein?
Participates in chain elongation of fatty acids.  Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA.  Has no 2,4-dienoyl-CoA reductase activity.
What are the official names of this protein?
Peroxisomal trans-2-enoyl-CoA reductase, TERP, 2,4-dienoyl-CoA reductase-related protein, DCR-RP, HPDHase, Short chain dehydrogenase/reductase family 29C member 1, pVI-ARL.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: TRHO_SODGM
Sequence: MPVLHNRVSNQELRARMLAESEPRTTVSFYRYFTLSDPQGFRDDLYRTLTALQVFGRVYIAAEGINAQISVLQSRFDAMREALYAAHPQLDGLRLNVALDDDGKSFWVLRMKVRPRIVADGIDDPTFNPANVGHYLKAEEVNALADDPQALFVDMRNHYEYEVGHFDQAIEIPSDTFREQLPMVVEMLQHDKDKKIVMYCTGGIRCEKASAWMRHNGFKNVYHVEGGIIEYARRAREQGLPLKFTGKNFVFDERLGERITPDIIAHCHQCGAPCDSHTNCRNQGCHLLFIQCPVCAEHYVGCCSVTCQEELSLPLSEQRSHRAGRENGMKIFNKSRERLQLSLTGEDSAQK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GLND_DECAR
Sequence: MSCDVAALRAEVKANQNQLRLNYEQSNDAVALLRDRCQHVDTVLEKLWLSLNFPASLALAAVGGYGRGELYPASDIDLLILLPQEASASLQEKLERLVGHFWDIGLEIGHSVRTVQECLDEAANDITVQTALLEARLLTGNTKLFATFQKRLRGNLDPLHFFEAKRLEQQERYLRFNETPYSLEPNCKESPGGLRDIQVIFWIAKAAGYGSTWAELHQNGIITQEEMIQMEGCEAYLNHLRIRLHFMLGRREDRLLFDYQSTLAANYGFVSNEAKRESEQLMQVYYRNAKTVTVLNTILLQNMGAALTPESEQTPQQLDESFQIVGNLLDIRDEQLYERNPLAILDSFLAMQESHELFGMTARTLRALWRAREQITPEFRANPENRAAFMKLLQGDRGIVHEFRRMNQLGILGRYLPNFGRIVGQMQHDLFHVYTVDQHILQVMRNIRRFTMSEFAHEYPLCSRIISELDRPWLLYVAALFHDIAKGRGGDHSELGTVDTREFCVNHGLSEEDTELVVWLVKNHLVMSQVAQKEDLSDPDVIANFIRLVGDTRHLQALYLLTHADIRGTSPKVWNNWKGKLLADLYYQAIHHINQGEAPAAHGVIAERQAEAMRLLRFFALSATVHERLWKQLDTVYFLRHSAEEIAWHTRSLHYRIYNNQPVVRARPNQEGDGLQVMVYTQDQPDLFARIVGFFARAGYSIVDAKIHTTAHGYALDSFVVLDIEERDNDREMVAYIEHELEQRLLHQMPRDVPSSGRLSRQVKHFPIKPEVSIRGDEKGTHFILSLVAADRPGLLYTVANTLTEHGAYLHTAKITTLGERAEDVFLISGGDLRDTHNRIRLETELMERLKV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RSMJ_ECODH
Sequence: MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_PHOLL
Sequence: MELTTRTMATAKNIALIAHDHCKTSLLAWSKKHKSLLKKHHLYATGTTGNLIQNETGLSVTNMLSGPMGGDQQIGSLISEGKIDVLIFFWDPLNSVPHDPDVKALLRLATVWNIPVATNLASADFIVSSPLFSESVDIQVPDYQHYLNGRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: SNX29_MOUSE
Sequence: MSGSQNDDRRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLALTAAAIKQAAGFTSKTETEPVFWVYVKEVLNKHELQRFYSLHHITSDAGRGRAWLRCALNEHSLERYLHMLLADRARLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGMSSLLREITASSAVSILIKPEQETDPLPVISKNVHVDTRCKRERRRRKKVTNIVSFDDDEEEQGTGDTLKKMPGTAESSEENSDRSSVNIMAAFEGTFGPNSNGSQSSSSWKIDSASLNGELGYQKLDVKSIDDDVDENEEDAYRSPLGRGHTGHAESPDRTLDGNACLAQVHGWAPLQVLHGDADADTDVLFPVSGVGSYGAADAPVGSLENGTGTENHIIPEPGLRYREASSPGQGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEAVPSLWNVDAEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYTEFRALHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAANPKKETLVQLVPFFVDITPPGEPLNKSSRPKAVSRFPKLSRGHPREVRNVEPQSGDL
What are the official names of this protein?
Sorting nexin-29.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
Protein: FADJ_SHEFN
Sequence: MSMEKTFNLARRDDGIAILTMDVPGETMNTLKEQFGPEISEILTEIKADSSIKGLVVISGKADSFVAGADITMLAACKNEEQAKTLSQQGHVVFAELEGLSIPVVAAINGACLGGGLELALACHLRVCSDDKKTMLGVPEVQLGLLPGGGGTQRLPRLVGITTALDMMLTGKQIRPKQALKMGLVNDVVPNSILLETAVELAKKGKQAAKPVVQSKINQFLESTSFTRDIIFDQARKQVLKKTQGNYPAPAKIIDCVRQGMNKGMVKGLEVEATHFANLVMSKESAALRSLFFATTEMKKETGAEGAVPRKVKKVMVLGGGLMGGGIASVTTTKAKIPARVKDISEQGLSNALSYAYKLLDKGVKRRHMTPIARDNIMALMTTTTEYTGIKDADIVVEAVFEDLALKHKMVQDVERECGENTIFASNTSSLPIGQIAAAASRPENVIGLHYFSPVEKMPLVEVIAHKTTSPETIATTVAFARKQGKTPIVVQDGAGFYVNRILALYMNEAAQLLLEGQRIEHLDRALVKFGFPVGPMTLLDEVGIDVGAKISPILEKELGDRFKAPAAFDKLLADDRKGRKNGKGFYQYGPKAKKAKLVDESVYKVLDILIASDKEAKGVAERCTIQMLNEAVRCLEEGIIASARDGDIGAIFGIGFPPFLGGPFRYIDTLGASNLVATLQGYQSLYGDRFAPCDTLVKMASDGSQFYKK
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_HALHL
Sequence: MELQGWILHCRAGYEQTLASEATMAAHERDVHGYCRARAQSAYVVFHAPAGDAPLPPQLVFARAGAGLIGELQGLPEGGRAEAIAAALPPAVGSATPWVEHPDSDAGRPLARFCRRFTGPLRHALTQTGVTSGDPQRRLRLLFPDSRHCFAGIGPREGWPSGIPRLRMPRNAPSRSVLKLEEALHRLVPENERPYPGEHAVDLGAAPGGWTWLLRERGLTVTAIDNGPLAPALADDPGVEHQRTDAFRFRPRTEVDWLVCDVVDRPQGIARLMTQWLREEWARAAIFNLKLPMRRPLETVRQALDAVRTTGARAHAAQLYHDREEITVYARRMASRNRP
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.