PharMolix/UniProtQA huggingface dataset:
Protein: IF3_DESVM
Sequence: MRRDIPQDTVRRNEQVRAREVRVIGADGEQLGILSRNDAIAHAKELGLDLVEVAATADPPVCRVMDYGRFKYEQQKKKAEAKKNQTVIQIKEIKVRPKTDDHDYDTKVRHIRRFIEEGDRCKVTVFFRGREIVHKDRGQSILDRIVEDTKDIAKMDQEARAEGRTLFMMLAPLPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_ECOLU
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLTLSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PYRR_PSEAB
Sequence: MSLPNPAELLPRMASDLRAHLAERGIERPRFVGIHTGGIWVAEALLRELGNQEPLGTLDVSFYRDDFTQNGLHPQVRPSALPFEIDGQHLVLVDDVLMSGRTIRAALNELFDYGRPASVTLVCLLDLNARELPIRPDVVGQTLSLGRDERVKLVGPAPLALERKVLSSAS
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: SPEA_TOLAT
Sequence: MANWSCQDALKMYNVPYWGAGFFNIDALGRVVVTPDKTRLDCKIALVDIIEQLRKQGYATPVLLRFPDIIKTRINALFGAFEQAIQSYGYKGRYQCVYPIKVNQQNQVIESVTRAFADKPALGLEAGSKPELLAVLSHHHDLGSVIVCNGYKDREYVRHALLGSLLGHHVYIVVEKPSELELILDEAARLNITPRIGVRARLASQGSGKWQASGGEKSKFGLNAAQILRLVERLREADKLDCLQLVHFHLGSQIANIRDIQGGIRECGRFYAELRHLGANIEVVDVGGGLGVDYEGSRSQSHCSANYNLREYANNVVWGIGDVCAEFDLPHPMIISESGRAITAHHAVLISNIVGMESQLPTSLPDAPDAEAPMLLQNMWDSWKELHEKEDPGLLEIFHDSVSDLADVHTQYTLGMLSLHQRAWAEDLHLNLCLKLKVMLDPVNRMHRNLQDELNEKLADKCFVNFSLFQSLPDAWGIDQIFPIMPLSGLDQQPTRRGVIMDITCDSDGMIKEYVDGVGIENSLPMPEMRNDETNYMGFFLVGAYQEILGDLHNLFGDTHSAEVCLNDNGEPVITNIIKGDNVDNLLRYVNIDTSVIRRDYQKLVAHPSLSEETRKALLEELEAGLQGYAYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: METK_DELAS
Sequence: MANDFLFTSESVSEGHPDKVADQISDAILDAIFAQDPYSRVAAETLTNTGLVVLAGEITTGANVDYIQVARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSQDIAQGVDKASDDELNTGAGDQGLMFGYACDETPELMPAPIYYAHRLVERQAQLRKDGRLPFLRPDAKSQVTMRYVDGKPHSIDTVVLSTQHSPDQSETATKMKASFTEAIIEEIIKPVLPSEWLQDTKYLINPTGRFVVGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLARQCQIQVAYAIGVARPMNITVYTEGTGVIPDAEIAKLVAAHFDLRPKGIIQMLDLLRPIYSKTAAYGHFGREEPEFTWERTDKAAVLRAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANCY_THEVB
Sequence: MGTFHRLTTTAGLQTALGTFSPATTVGFVPTMGALHGGHAALIRRARQECDVVVVSIFVNPLQFGPQEDLERYPRALEADTALCQQLGVDLLFVPSVAELYPTGMKHLTVVEPPRELTEHLCGRSRPGHFRGVATIVLKLLHLVQPDRAYFGQKDAQQLAIIRRCVADLNLDVEIIGCPIVRDADGLALSSRNQYLSAEERATALALSQSLEVAQAAFRQGCWDASLLLAQVQDHLRQFPQLRLDYAELVHPQTLVPLERIETVGLLAIAGWVGQTRLIDNCLLDRRRPILAVDGPAGAGKSTVTRLAAQALGLRYLDTGAMYRAVTWWCLENNLDLHDEPAIVEAIAHCRLHLESPDPHQPTRVWINDREVSQAIRSLEVTQRVSQIAALRGVRRLMVQQQRAIGAHGGIAAEGRDIGTHVFPEAGLKIFLTASPEERAQRRWQELQQQGHCDLSYEELLAQITARDTADQQRPYAPFRKAADAIEVCTDNLGIDEVVSKIVHLYRSRFPQP
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_XANCB
Sequence: MARSLKKGPFVDHHLAKKVESAAGSKKPIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNENMVGHKLGEFAVTRTFKGHGGDKKSSR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: EFTU_RHIRD
Sequence: MAKSKFERNKPHVNIGTIGHVDHGKTSLTAAITKYFGEFKAYDQIDAAPEEKARGITISTAHVEYETPARHYAHVDCPGHADYVKNMITGAAEMDGAILVCSAADGPMPQTREHILLARQVGVPAIVVFLNKVDQVDDAELLELVELEVRELLSSYDFPGDDIPIIKGSALAALEDSDKKIGEDAIRELMAAVDAYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIRPTSKTTVTGVEMFRKLLDQGQAGDNIGALVRGVTRDGVERGQILCKPGSVKPHKKFMAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIVSLPEGTEMVMPGDNVTVEVELIVPIAMEEKLRFAIREGGRTVGAGIVASIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KV5A9_MOUSE
Sequence: MVSTPQFLVFLLFWIPASRGDILLTQSPAILSVSPGERVSFSCRASQSIGTSIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQSNSWP
What are the official names of this protein?
Ig kappa chain V-V region L7.
Protein: PDRP_RHIL3
Sequence: MENRTNFFHLHLISDSTGETLISAGRAASAQFRSAQPIEHVYPLIRNRKQLLPVLQAIDDAPGIVLYTIVDRELASLIDERCIEMGVASVNVLEPVMNAFQIYLGAPSRRRVGAQHVMNAGYFARIEALNFTMDHDDGQMPDDYNDADVVIIGISRTSKTPTSIYLANRGIKTANIPIVYGVPLPESLFVASKPLIVCLIATTDRISQVRENRVLGVTQGFDREHYTDRAAISEELKYARSLCARHNWPLIDVTRRSIEETAAAIVALRPKLR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: LGT_KLEP7
Sequence: MNSGYLHFPEFDPVIFSLGPVSLHWYGLMYLVGFVFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNLPVFLADPLYLFRVWDGGMSFHGGLIGVILVMIIFARRTKRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPSFHYTMIFPGSRAEDLALLPTHPEWQSLFDTYGALPRHASQLYELALEGVVLFLILNLFIRKPRPTGSVSGLFLIGYGLFRIIVEFFRQPDAQFTGGWVQYISMGQILSIPMVLAGIIMMVWAYRHRPQQQNS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIM1_OCEIH
Sequence: MQVDIIKQVRDTKPLVHHLTNQVVMNFSANGLLSFGGSPIMAKAIEEVEQIAAISNAVLINIGTLTSTELESMIAAGKTANKHNIPVLLDPVGVAATSFRRNAIDKILEEVRPTVIKGNAGELASLVNINLEAKGVDSIGDGNLDVIAQKVSEKYNTAVVVTGETDVIYVDNHLIHNGTGHHYLSSITGSGCLLGSIIAACLTTKSTLKDQLMTAVSFYGLSASYAANQENVHGTGSFLPVFIDSLSKMPQELTEGE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 1, 4-methyl-5-beta-hydroxyethylthiazole kinase 1, TH kinase 1, Thz kinase 1.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: TUSB_SALA4
Sequence: MLHTLPHCASGVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_CAMJ8
Sequence: MENEKNYRPNVAAIVLSSSYPFECKIFIAKRSDMDNIWQFPQGGIDKGESVKNALFRELKEEIGTDEVEIIAEYPEWLSYDFPSKIVKKMYPYDGQIQKYFLVRLKHGATININTKHPEFDDYQFVSVKQIFEMINHFKKNIYVKVIKYFEEKGYI
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: KDSA_XYLFM
Sequence: MKLCGFEVGLNQPLFLIAGPCVIESLQLQLDTAGVLKEITSKLGLNFIFKSSFDKANRTSGSSFRGPGLEEGLKVLEAVKTQIGVPVLTDVHEYTPIDEVATVVDVLQTPAFLVRQTDFIRNVCAVGKPVNIKKGQFLSPWDMKPVVEKAKSTGNSQILVCERGASFGYNNLVSDMRSLAVMRETGCPVVFDATHSVQLPGAQGGRSGGQREFVPVLARAAVAVGISGLFAETHPDPPNALSDGPNAWPLRTMAMLLETLVELDAVTKKRGFLEQD
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_ECOLI
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.  In vitro, active on the assembled 30S subunit, but not naked 16S rRNA or 70S ribosomes.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTG_HAHCH
Sequence: MEKFTMSETKVWSGRIDSADGPTAVRWHQQVRAPQEDSPAGVALIGYPCDLGVYINKGRVGAANGPDEIIKALANLPWRLTHPVYDCGNIQWEGELEDAQAALATKVFKQLQAGHSPIVLGGGHDVAWGSFQGLRRHLDQAAPDKVLGILNLDAHFDLRSDSEGASSGTPFQQIAKYCKTAGKPFHYAVFGISEYANTQALFDRADKLGVTYLKDTHCGYTQLGPMLRALDAFLSKVDCLYLTIDLDVLPAATAPGVSAPAAYGVPLEIVEAMLDAIQRKALPVLMADIAEYNPTYDIDSRTARVAARLAARLAGLLGKPTTKA
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: TRMFO_BACAN
Sequence: MTTQVVNVIGAGLAGSEAAYQIAKRGVQVRLYEMRPVRQTPAHHTDKFAELVCSNSLRANTLTNAVGVIKEEMRLMDSVIIRAADECSVPAGGALAVDRHEFAAKVTEYVKNHPNVTVMNEEITEIPEGPTIIATGPLTSPDLSAQLKELTGEDYFYFYDAAAPIVEKDSIDMNKVYLKSRYDKGEAAYLNCPMTEEEFDRFYEALIAAETVPLKEFEKEIFFEGCMPVEVMASRGRQTLVFGPMKPVGLEDPKTGKTPYAVVQLRQDDAAGTLYNIVGFQTHLKWGPQKEVLQLIPGLENAEIVRYGVMHRNTFINSPNLLRPTYQYKQRDDLFFAGQMTGVEGYVESAASGLLAGINAARLVKGEEPVVLPPVTAMGSMANYITATNAKNFQPMNANFGLFAPLEKKIKKKAERNEAYATRALEMIRNFVNI
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGSA_SALTY
Sequence: MQFNIPTLLTLFRVILIPFFVVVFYLPFAWAPMVSALIFCIAAITDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMLQYLSAARGDLLDQ
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNJC9_HUMAN
Sequence: MGLLDLCEEVFGTADLYRVLGVRREASDGEVRRGYHKVSLQVHPDRVGEGDKEDATRRFQILGKVYSVLSDREQRAVYDEQGTVDEDSPVLTQDRDWEAYWRLLFKKISLEDIQAFEKTYKGSEEELADIKQAYLDFKGDMDQIMESVLCVQYTEEPRIRNIIQQAIDAGEVPSYNAFVKESKQKMNARKRRAQEEAKEAEMSRKELGLDEGVDSLKAAIQSRQKDRQKEMDNFLAQMEAKYCKSSKGGGKKSALKKEKK
What is the function of this protein?
Acts as a dual histone chaperone and heat shock co-chaperone (PubMed:33857403).  As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers; and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes (PubMed:33857403).  May also act as a histone co-chaperone together with TONSL (PubMed:33857403).  May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers (PubMed:33857403).  Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8 (PubMed:17182002, PubMed:33857403).  As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity (PubMed:33857403).  Exhibits activity to assemble histones onto DNA in vitro (PubMed:33857403).
What are the official names of this protein?
DnaJ homolog subfamily C member 9, HDJC9, DnaJ protein SB73.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Predominantly nuclear. Translocates to the cytoplasm and membrane after heat shock.
Protein: Y3G1_ENCCU
Sequence: MAEVSKKRCEHNSDSQCEGCKANDKACEARDKTKETAGSAKDKTKETAGSAKDKTKETAESAKDKTKETAGSAKDKTKETAESAKDKTKETAGSAKDKTKETAESAKDKTKETAGNVRDNVENKDKNEVYENIKEGGSKAWNKTKEVANSMKDGIKDLANKDEQKK
What are the official names of this protein?
Uncharacterized protein ECU03_1610.
What is the protein family that this protein belongs to?
Belongs to the LEA type 1 family.
Protein: ACT8_XENLA
Sequence: MAEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKPCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoplasmic type 8.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: BI1_RAT
Sequence: MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTRFIQAGLLSALGALALMICLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAINPSILPTAFMGTAMIFTCFSLSALYARRRSYLFLGGILMSAMSLMFVSSLGNLFFGSIWLFQANLYMGLLVMCGFVLFDTQLIIEKAEHGDKDYIWHCIDLFLDFVTLFRKLMLILAFNEKDKKKEKK
What is the function of this protein?
Suppressor of apoptosis.  Modulates unfolded protein response signaling.  Modulates ER calcium homeostasis by acting as a calcium-leak channel.  Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation.
What are the official names of this protein?
Bax inhibitor 1, BI-1, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIS4_ANADE
Sequence: MLVIPAIDLIGGEVVRLEKGDFAKKTVYARDPAEKAAELVRDGATLIHVVDLDGAKAGWPVNLDAVRAICAVPGAEVELGGGLRSLPDIEKVLELGVRYVVLGTAAVERLDLVRQACARFPGRVRSGIDARNGEVKIAGWLEGTGLGAAEVARRVKEAGVGLVEYTDVGRDGMFTGVDADGAARLQAEAGVQVVASGGVASLDDVRACRAAGLAGVIVGKALYEGRIALADAVRTAAE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_FRATO
Sequence: MDNLNINFINDDEHPIPSQDLLLKCLQLVADKHHISHAEVNLNIVSNDEIQQINKQFRNKDKPTNIISFEFEKPQGLPDDIANDFLGDIVIAPAVLENEAKEQNKEINDHWQHIFIHGLLHLLGYDHQDDQEAEVMENLEIQLLAQLGIANPYIEQENQNGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_LEPBJ
Sequence: MSLWISGIPIHYYLILAMIIFTIGVAGVMVRRSAVLIFMSVELILNSVNLVFVTFSKALYQVDGEVVVFFVMAIAAAEAAIGLAIVIAIHRIKKTSYVDEMNLMKW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THS_PYRAB
Sequence: MAQLAGQPILILPEGTQRYVGRDAQRMNILAARIIAETVRTTLGPKGMDKMLVDSLGDIVITNDGATILDEMDIQHPAAKMMVEVAKTQDKEAGDGTTTAVVIAGELLKKAEELLDQNIHPSIVIKGYMLAAEKAQEILDSIAKEVKPDDEEVLLKAAMTAITGKAAEEEREYLAKLAVEAVKLVAEEKDGKFKVDIDNIKFEKKEGGAVSDTKLIRGVVIDKEVVHPGMPKRVEKAKIALINDALEVKETETDAEIRITSPEQLQAFLEQEEKMLKEMVDKIKEVGANVVFVQKGIDDLAQHYLAKYGILAVRRVKKSDMEKLAKATGAKIVTNIRDLTPEDLGEAELVEERKVAGENMIFVEGCKNPKAVTILIRGGTEHVVDEVERALEDAVKVVKDILEDGKIIAGGGAAEIELSIKLDEYAKEVGGKEQLAIEAFAEALKVIPRTLAENAGLDPIETLVKVIAAHKEKGPTIGIDVYEGEPADMMERGVIEPVRVKKQAIKSASEAAIMILRIDDVIAAQKLEKEKEGEKGGGGSEDFSSSSDLD
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit, Chaperonin subunit.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: GRASP_MOUSE
Sequence: MTLRRLRKLQQKEEATAAPDPAGRAPDSEAARAAPLPSGPPAAAAPPGAPGEELYAALEDYHPAELYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGSARGGARRAKGDTDDAVYHTCFFGGAEPQALPPPPPPARALGPSSAETPASVLFPAPRSTLSRSASVRCAGPGGGGGAPGALWTEAREQALCGAGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL
What is the function of this protein?
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
What are the official names of this protein?
General receptor for phosphoinositides 1-associated scaffold protein, GRP1-associated scaffold protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane.
Protein: RS21_PARUW
Sequence: MSLVKVRIGDSIDKALRALKKRLDKEGVMKSVKAHRFYSKPSIKKRAKSKAALKYKKQR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PYRH_NEIMB
Sequence: MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVKMGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARVQSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVMLKATNVDGVYTADPKKDPSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGIAKEGSLKRVITGEDEGTLVHC
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_SALA4
Sequence: MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAAIRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGGERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWAMAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGTGE
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.