PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_VEREI
Sequence: MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVTDPGMTALKKLSIMSEEDYEAKRKEYGDEFIAKMGAEGIKDLLESIDIDLSIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLQVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSVEAQMEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYYATRDRINGKGEGLVFADTGEVQRAFDAGEVELAARITVRLTEWSKPKDSDALVPTTALVETTAGRALLSEILPPGLPFSYVNKALKKKEISRLINVSFRKCGLKATVVFADKLLQNGFRLATRAGISIAIDDMLVPPQKAGIIERSEREVKEFEQQYVSGLVTAGERYNKVVDIWGKAGDEVSKAMMAQLSKEQVIDRHGQQVSQESFNSIYMMADSGARGSAAQIRQVAGMRGLMAKPDGSIIETPITANFREGLNVLEYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEEDCETANGSLMRAIVEGGEVIESLRDRILGRTAAEEVLHPENRMVLVPVGVMLDEDLIEELEAAGVDEVKVRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAVIASRVEAKSNGVIGFSSTMRYVSNTKGELVVIARSGEIVIHDEYGRERERHKVPYGATLTVNADQNVKAGTVLAKWEPLTRPIITEFAGRTKFENVEEGLTVARQLDEVTGLSTLVVIDPKRRGAAKVVRPQVKLIDAQGNEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVLARIPVEGQKTRDITGGLPRVAELFEARTPKDKGTLAEMTGTVSFGKETKGKVRLQITDPEGHVFEELVPKEKNILVHEGQVVNKGESIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVEDAGESNYISGEQVERSEILNTNEALRAAGKIPAVYSNLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKDAMDDAERRAIADAEAAEMAAQAEVPELDGSSVTASDAAAD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: GLPX_MYCLB
Sequence: MTAEGDGSFKPGPPTERRGEAPDRNLAMELVRVTEAGAMAAGRWVGRGNKEGGDGAAVDTIRELVNTVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPDCDFAVDPIDGTTLMSKGMPNAISVLAVADRGAMFDPSAVFYMNKITVGPDAAHVLDITAPIGENIRAVAKVKDLSVRDMTVCILDRPRHAQLIDDVRATGARIRLITDGDVAGAISACRPQSGTDMLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDVERRKALDAGYNLDRILTTEDLVSGENVFFCATGVTDGDLLKGVRYYAGGCTTQSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDNNAAYPLP
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAZA3_HUMAN
Sequence: MTLSVLSRKDKERVIRRLLLQAPPGEFVNAFDDLCLLIRDEKLMHHQGECAGHQHCQKYSVPLCIDGNPVLLSHHNVMGDYRFFDHQSKLSFKYDLLQNQLKDIQSHGIIQNEAEYLRVVLLCALKLYVNDHYPKGNCNMLRKTVKSKEYLIACIEDHNYETGECWNGLWKSKWIFQVNPFLTQVTGRIFVQAHFFRCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENKFQAAVLEELQELSNEALRKILRRDLPVTRTLIDWHRILSDLNLVMYPKLGYVIYSRSVLCNWII
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.  May play a role in the morphogenesis of spermatid (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-3, CapZ alpha-3, CP-alpha-3, Germ cell-specific protein 3.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: CHM1A_HUMAN
Sequence: MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVRSQEDQLSRRLAALRN
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  Involved in cytokinesis.  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.  May also be involved in chromosome condensation.  Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin.  May play a role in stable cell cycle progression and in PcG gene silencing.
What are the official names of this protein?
Charged multivesicular body protein 1a, Chromatin-modifying protein 1a, CHMP1a, Vacuolar protein sorting-associated protein 46-1, Vps46-1, hVps46-1.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Nucleus matrix. Note=The cytoplasmic form is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with the chromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized by nuclease-resistant condensed chromatin.
Protein: APRG1_HUMAN
Sequence: MKTMATRKRCKLSRTGPEFENVIKRLLCARTFHTRIGGDLTHGIINRGRRANAEQMGLQGSAQHFNIFPLDLWTQGKKTEVQKREGTDSIPAAGRSGTANQPSIAPHRCLFSRGITALDGLKRGRGCNGAAHLVRGDAWKTKLGEPWVSIALALAGPGAILILELSWFLG
What are the official names of this protein?
APRG1 tumor suppressor candidate, AP20 region protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSBI_CYAM1
Sequence: MLTLKIFVYTCVIFFSSLFIFGFLSNDPSRNPNRKDLE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COAD_CLOBA
Sequence: MKVAVYPGSFDPITNGHLDIIERGSKVFDKLIIGVLVNVDKKGLFEIEERVELIKKVTKHIKNVEVISFNGLLIDFLKAYNAKIILKGLRAVSDFEYEFKMALMNNKLDPDIETVFMMTSAQYSYLSSSSVKQVAKFGGCIEGLVPKEIISDVVRRSKI
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX622_PSACA
Sequence: GACRWFLGGCKSTSDCCEHLSCKMGLDYCAWDGTF
What is the function of this protein?
Selectively activates the mammalian capsaicin receptor TRPV1, a non-selective cation channel expressed by sensory neurons of the pain pathway.  Is more potent than VaTx1, but less potent than VaTx3.  Interacts with distinct regions of the channel than capsaicin, since it only acts on the extracellular face of the channel, and capsaicin binds to the cytosolic side.  Also activates avian TRPV1, which is insensitive to capsaicin.  Produce weak inhibition on potassium channels Kv2. 1/KCNB1.
What are the official names of this protein?
Tau-theraphotoxin-Pc1b, Tau-TRTX-Pc1b, Vanillotoxin-2, VaTx2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 62 (Vatx) subfamily.
Protein: EEIG1_MOUSE
Sequence: MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVRKELKGGKAYSKLGFTDLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKTRPTILGSGLPEEPDQSLSSPEEVFHSGHSRNSSYASQQSKLSGYSTEHSRSSSLSDLTHRRNTSTSSSASGGLSMAVEGPEGMEREHRPSEKPPRPPEKPPRPPRPLHLSDRSFRRKKDSVESHPTWVDDTRIDADDIVEKIMQSQDFTDGSNTEDSNLRLFVSRDGSTTLSGIQLGNRVSSGVYEPVVIESH
What is the function of this protein?
May play a role in estrogen action.
What are the official names of this protein?
Early estrogen-induced gene 1 protein, EEIG1.
What is the protein family that this protein belongs to?
Belongs to the EEIG family.
Protein: RL27_CANLF
Sequence: MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEEKYKTGKNKWFFQKLRF
What is the function of this protein?
Component of the large ribosomal subunit (By similarity).  Required for proper rRNA processing and maturation of 28S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
60S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: SYN_LEGPL
Sequence: MTEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLSNYQKEVTKLTAGCSMIATGKLVASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLEFLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFWVHTPIITASDCEGAGEMFRVSTLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSNTSRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIERMEHIADSEFEIMTYTDAIKALEASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNYPQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEILDRRMDECNLNKEHYQWYRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1188_VIBCM
Sequence: MLILLMIKKIAQYCVSMGLIFLCLLAGINLQTWLGIAIPGSIIGLLILFGLMASGLVPVEWVKPSATLFIRYMILLFVPISVGLMVHFDTLLANLAPILASAIGGTLIVMVTLGLILDRMLKKGKKSCG
What are the official names of this protein?
UPF0299 membrane protein VCM66_1188.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RISB_BACC1
Sequence: MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEEADIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CATI_PSEKB
Sequence: MAELLTLREAVERFVNDGDTVALEGFTHLIPTAASHEIIRQGKKDLHLVRMTPDLVYDLLIGAGCARKLTFSWGGNPGVGSLHRLRDAVEKGWPNALEIDEHSHADLANSYVAGASGLPFAVLRAYAGSDLPKVNPNIKFINCPFTGEQLAAVPSVRPDVTVIHAQKADRKGNVLLWGILGVQKEAALAAKRCIVTVEEIVDDLNAPMNSCVLPTWALSAVCHVPGGSHPSYAHGYYERDNRFYQAWDPIARDRETFTAWIDEYIRGTKDFSEFQAKIAEGK
What is the function of this protein?
Catalyzes the CoA transfer from succinate to 3-oxoadipate (beta-ketoadipate).
What are the official names of this protein?
3-oxoadipate CoA-transferase subunit A, 3-oxoadipate:succinyl-CoA transferase subunit A, Beta-ketoadipate:succinyl-CoA transferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: RS2_TRIL1
Sequence: MSSISMKELLEAGVHFGHQTKRWNPKMKPYIFGARNGIYIIDLQKTVRYFKSAYNFVKESAEQGNTVLFVGTKKQAQDSVAEEATRCGQYYVNQRWLGGMLTNFSTVKQSIERLKKLDAMFEDGTIEAYTKKEALKMDKEREKLEKVLGGIKNMNKLPGMMFVIDPKNEEIAVQEAKKLGIPVVAIVDTNCDPDMIDHVIPGNDDAIRAIRLLTAKIADAVQEGADARNVVLQSGAEGADDLEEALADEVACEASAD
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MASZ_CHRSD
Sequence: MTDRTTRHRLQVASQLDRFINDEALPGTGVDPEAFWAGFDALVHELVPTNRDLLAERERLQDELDAWHKANPGPVRDMAAYRAFLKDIGYLVEAPAKVQATTANVDDEIAVQAGPQLVVPVSNARYALNAANARWGSLYDALYGTDVIPETDGAEKSQGYNPKRGEKVIAYARGVLDQAAPLAEGTHAEASAYALRDGKLVVTLQGGGETGLADPAQLVGYRGEAQAPTAVLLANHGLHLEVQFDATHPIGKTDPAHVKDVLVEAAVSTIMDCEDSVAAVDADDKTLVYRNWLGLMKGDLEERFDKGGKTVTRALNPDRDYTVPGGGELRLPGRSLLFVRNVGHLMTTPAVLDGDGNEIPEGMLDGVVTSLLAIHDLKKGDGAAPSATAPEAKRNSRTGSVYIVKPKMHGPREVAFANSLFMRIEDMLGLPRDTLKMGIMDEERRTSINLDACIHEAASRVAFINTGFLDRTGDEMHTAMEAGPMLRKGEMKGTKWIAAYEKNNVQTGLACGLRGRAQIGKGMWAMPELMAAMLEQKIGHPQAGATTAWVPSPTAAVLHALHYHQVDVATIQRELEAKPGGDFLDDLLTVPVVESAASGANKSPSWSDDEIQQELDNNCQGILGYVVRWVEHGVGCSKVPDIHDVGLMEDRATLRISSQHIANWLHHGIVSEARVRETLERMAKVVDDQNAHDPDYTPMTSHLAESCAFQAASDLIFKGREQPAGYTEPLLHHWRAVHKAKS
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_STRZT
Sequence: MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISLQDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSRLLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIKNGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHEIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IR03_HCMVA
Sequence: MYCFLFLQKDTFFHEQFLARRRHAEVGPLRSAACRRRPGDLGFTVFSLLSLHTDRVAGAVRNHRRLSFFDDYGNTKSYLGAYTSKIGVLVVVCGFYFFLYLSMTVFLFFVLIII
What are the official names of this protein?
Uncharacterized protein IRL3, TRL3.
Protein: UBL4A_HUMAN
Sequence: MQLTVKALQGRECSLQVPEDELVSTLKQLVSEKLNVPVRQQRLLFKGKALADGKRLSDYSIGPNSKLNLVVKPLEKVLLEEGEAQRLADSPPPQVWQLISKVLARHFSAADASRVLEQLQRDYERSLSRLTLDDIERLASRFLHPEVTETMEKGFSK
What is the function of this protein?
As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation (PubMed:20676083, PubMed:21636303, PubMed:21743475, PubMed:28104892).  The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane.  Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum (PubMed:20676083, PubMed:28104892, PubMed:25535373).  Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome (PubMed:28104892).  Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum (PubMed:21743475).  The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome.  It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome (PubMed:21636303).
What are the official names of this protein?
Ubiquitin-like protein 4A, Ubiquitin-like protein GDX.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: RS17E_PYRIL
Sequence: MGRVKPKYIKSLARRLLETYPDKFTDSFEENKKAVAQLADIPSKTVRNKVAGYITRLVKRLKTQEKTESAA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: FABH_RHORT
Sequence: MWRSVIAGCGSYLPANKVTNANLAERVETTDAWIRERTGILVRHFAAEGEKTSDLAMAAARAALADAGVDAAEVDLIVLATATPDQTFPATATRVQAGLGCRPGAPAFDIQAVCSGFLYALSVADALIKAGQARTALVIGAETFSRILDFTDRTTCVLFGDGAGAVVLRATPSTGDGGERGILSTHLHADGRHHDLLYVDGGPSSTGTVGHLRMQGREVFRHAVTNLYEVVLEALAANGLQADAIDWVVPHQANQRILDGTAKKLGIDPAKVISTIALHANTSAASVPLALCEARRDGRIQPGQLILLEAMGGGFTWGSALVRL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_BREBN
Sequence: MNIILMGLPGAGKGTQAERIVKEFDIPHISTGDMFRAAVKNETPLGLEAKSYMDKGHLVPDEVVIGIVRERLSMDDCAKGFLLDGFPRTVPQAEALTATVKELGREIDHVININVQREQLIERLTGRWICPVCGASYHTMFNPPKEAGVCDKDGGKLYQREDDKIEVVTQRLDVNIAQTQPLIDYYSAQELLRDIDGEQDIQVVFAEIKSLLRG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_AGRRK
Sequence: MVTILDRINPDAKRVRHPEKAHRPDTEVLRKPDWIRVKAPTSKGYAETRSIVKEHKLVTVCEEAGCPNIGECWEKKHATFMIMGEICTRACAFCNVATGKPNALDMAEPENIAKAVKEMGLSHVVITSVDRDDLADGGAEHFEKVIWAIRAASPMTTIEILTPDFLKKPGALERVVAAKPDVFNHNMETVPGNYLTVRPGARYFHSVRLLQRVKELDPTMFTKSGIMVGLGEERNEVLQLMDDLRTADVDFLTIGQYLQPTRKHHQVMSFVTPEEFKSYETVAYTKGFLMVASSPLTRSSHHAGDDFARLRAAREKKILLAAE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARMC8_XENLA
Sequence: MACVLEPPLRMSVLSEVTASSRHYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLSMGTENNVKSLLDCNIIPALLQGLLSSDLQFIEACLRCLRTVFTSPVTPVELLYTDASVIPHLMLLLSRSIYAQEYICQIYAHCCKGPDHQTILFNHGVVQNIAHLLTSVSYKVRMQALKCFSVLAFDNPQVSMTLANVLVDGELLPQIFAKMLQRDKPIEMQLTAAKCLTYMCRAGSIRTDDNCIVLKTLPCLVRMCSKERLLEVRVEGAETLAYLIEPDVELQRIASITDHLISMLADYFKYPSSVSAITDIKRHQETGQPCIDPEEAEPRGTRDESQCTALSISHPVSQIQHDCLLTSEELDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIEAEHMMDRIVNGLSETSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDDILVVASSTLCNLLLEFSPSKEPILESGAVELLCSLTLSENPALRVNGIWALMNMAFQADQKIKSDILRGLSTEQLFQLLSDSDVNVLMKTLGLLRNLLSTRPHIDQIMSTHGKQIMQAVTFILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYVGHSNLKLQLAAMFCIANLTWNEEEGSQERQDKLREIGIVDILHKLSQSTDPNLCDKAKTALQQYFA
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Armadillo repeat-containing protein 8.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EXPH5_HUMAN
Sequence: MTKVPPAFDFSFLNDEEARKILQVLERNEELQRAEKDRISKLQKTKRDIRWLQGVTGEWFEEIQRKKFCNETDVSQMLKQPLTYRLSKEMAKNDPIELPTSRSKNVTNQKKPTPFSSRMSFRSSFASLFSFRKSGKETSKLPSLGQKGCDGHAGPPMPVRGAAVQAKIYNSPLENHLVDSTFVPKPAVMREESGMPPPWDASLLENEFFQVLDDLDSKLAQEQSASSVNTRTPLNYGSRTQFGHFYSSGNRHGNITERHKKHYNETSNMSIYDILRPGTPREGFKTFSPRTSTIYDMYRTREPRVFKEDYVQKNTFGSTSLCFDSRQRSALPATGHFTARSLHFPATTQSKSGFIPPRHQQSPKRTPLSSIIWNRSDSSRDRENQEEFLRAPSPMEIDPADKYVYPRGFQENKRYESYHSQNVYQRVSLNAPMENAMSPDTFENSENMPFYHQSNTFTRSFFSNTFGRSGEQRRFGQGPFWGQEKGHSFWSDFHRSRKSFSSSDRDFEMISMEANSVSAIHGHNVSSEHWESFSSGYGTDVSRGQEEPHPWQFDFQRSTLDSMVVSHGNETQLTPHFGTPNVCSMTGSSYHVKSSELVSQQDSSPVEVHINKEASSFGIAQTLASSFKTSFSQISDDRRNPQSPNLQNPTVTLQKIFPNKPASHPMRSHTEVTVTSSNSVDSLPLAKSQPNILVTEVNNEKDLNESISEEDKQLSKMDQTNKAGEIPQPVSQTGISNSLPDFQNPLSQDSAKSNGFGFNASTIISSKKSPRVFSRKDTSKMYIPHTDKSNDIKQDKRFTENRKLGSTASLPFIQEHRTPPSFPRTDQGCHQELTVNNEDISRIITNNHWSSALTDTQNAQYSKCKLTPGHKTSCDSLDLSSAALPDSSPSKNSSLDAPVVPSTTVFSRRSPSDKDPSLGEREEKDNAGKNQKNQFIVSHSENQERNDSPVPTHDEVVDVKCHSHSPFRNERGKGKIRHHISCIEKLSKTESISVPTSDHRSLIEANQSNSKVSELDTIYCTLPRKSSSFLIHGRQSGSKIMAASLRNGPPPFQIKNNVEDAMGNYMLNKFSPSSPESANECSKVLSDSALEAPEATERMTNVKSSGSTSVRKGPLPFLINRAMSCPSGEPHASTGREGRKKPLTSGMDASELTPRAWERIISPVESDSSVRDCSLTKRQHQKENFQEYTEKEGKMAASRRSVFALSNEDPLPFCSDLSGKERGKTLHKVKTTSTFSVSGDEDNVKCLEVVSIYYTLPRKPSKKFCNLLQQYTQNTNLLIESPQVETETFPNALEKDKQNYSTREQSGTPSCENLKMSVNSDQTLTTENMTAFRLSNRGPLAPTLQEMASVEAAVSLPEEESKAREIFSDNLAKTPLGDSENKKERGKKLQSETLHTSLMLQRKNVSEEKSENCQQSINSSNSGPSSLPALSEVNIGNSQTRRSSWECTGSGRAIPFTGSGKCPQKDHTSTAVGDGSSGSQPREGRGDIGTNCQKMTNKTLSHSESQVFALTPALHKLQLGEETQSDEPNLESLQSEPRELPQRSQEANMTESRKAEDEMQKSAWDQPSLPEGNKNKTNLDDLVKGENRSSVKHRLAAMSKASRKFPAKDVSPRRHVATIFPQSGSRSGFDHLSLGTVECNPLFPEPTPKSAESIGESRLSENGKHVKKSENLLPITVLPNREPSTHVSNQKSNSISQRHQNEFKNVSESPSKHENSKDVTAAQNLVRESGAPSPITFTSLREAEFSDNQRRLSPPFPLEPAQKSRVSSPLASFLQQQRSASSLEWEPEPHLYRSKSLKSINVHGDLLRKSHPPKVRERHFSESTSIDNALSRLTLGNEFSVNNGYSRRFRSFSELPSCDGNESWAYRSGTKTGPRSAISIYRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDLRNPPNPSESLSSNSPSSQVPEDGLSPSEPLNIYEDDPVDSDCDTDTTTDDEYYLDENDKESEL
What is the function of this protein?
May act as Rab effector protein and play a role in vesicle trafficking.
What are the official names of this protein?
Exophilin-5, Synaptotagmin-like protein homolog lacking C2 domains b, SlaC2-b, Slp homolog lacking C2 domains b.