PharMolix/UniProtQA huggingface dataset:
Protein: GPT1_ARATH
Sequence: MVLSVKQTLSPKIGLFRRNPSSSLGRSPVSLSFPSTELPKRTVLAVSKPLHLSSSLRAKSPVVRCEAYEADRSEPHPIGDDAAAAETKSEAAKKLKIGIYFATWWALNVVFNIYNKKVLNAYPYPWLTSTLSLAAGSLMMLISWAVGIVETPKTDFDFWKTLFPVAVAHTIGHVAATVSMSKVAVSFTHIIKSGEPAFSVLVSRFILGETFPTSVYLSLIPIIGGCALSALTELNFNMIGFMGAMISNLAFVFRNIFSKKGMKGKSVSGMNYYACLSMLSLLILTPFAIAVEGPQMWVDGWQTALATVGPQFVWWVVAQSVFYHLYNQVSYMSLDQISPLTFSVGNTMKRISVIVSSIIIFRTPVQPVNALGAAIAILGTFLYSQAKL
What is the function of this protein?
Glucose 6-phosphate (Glc6P) transporter (PubMed:15722468).  Transports also inorganic phosphate, 3-phosphoglycerate, triose phosphates and, to a leser extent, phosphoenolpyruvate (PubMed:15722468).  Responsible for the transport of Glc6P into plastids of heterotrophic tissues where it can be used as a carbon source for starch biosynthesis, as substrate for fatty acid biosynthesis or as substrate for NADPH generation via the oxidative pentose phosphate pathway (OPPP) (PubMed:15722468).  Required for pollen maturation and embryo sac development (PubMed:15722468, PubMed:20659277).  Preferentially exchanges Glc6P for ribulose-5-phosphate (Ru5P) in reconstituted yeast proteoliposomes (PubMed:32111666).  May supply the substrate (Glc6P) for OPPP reactions inside peroxisomes and exchange it with the product Ru5P which leaves the organelle (PubMed:32111666).
What are the official names of this protein?
Glucose-6-phosphate/phosphate translocator 1, chloroplastic, AtGPT1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. GPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Multi-pass membrane protein. Note=Targeted to peroxisomes via the endoplasmic reticulum.
Protein: PURQ_SULDN
Sequence: MKVTILQFPGTNCEYDAQHAFKSLGAETEILWHKSDTIPSDTDLLIVAGGFSYGDYLRSGAIAKFSPVMKAVIKYADDGGKVLGICNGFQVLTESGLLPGALKRNESLHFLSKHHHLKVINNENIFLEKLDKGDIVNIPIAHHDGNYYIDDSGLKELYANNQVLLKYCDENGNDKNPNGSIDSIAGICNKERNVFGLMPHPERAMEAILGSDDGIKMLQGFLRA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_NOSP7
Sequence: MRTHYCGELRKEHIGETVTFYGWVDRRRDHGGVVFLDLRDRSGIVQIVSDPQRTPDSYEQANALRNEYVVEITGRVTQRPEESLNTRIPTGEVEIYADKIKLLNAVGKQLPFQVSVADTETVREDLRLKYRYLDLRRERMAQNLQLRHQIVKAMRRYLEDLEGFIEVETPILTRSTPEGARDYVLPSRVNPGEWYALPQSPQLFKQLLMVSGLDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSQEEIIELNESLVCHIFKTVKGIELQRPFLRLTYAEGMERYGSDKPDTRYGLELVDVSDIVKDSGFKVFRDTVTNGGIVKILPIPNGNDVISNVRIKPGGDLFKEASEAGAKGLAYIRVRDDGEIDTIGAIKDNLSEEQKQEILRRTGAKAGHLLLFGAGEAATVNKTLDRLRQAIAREFNLIDPDKINLLWITDFPMFEWNADEKRLEALHHPFTAPHPDDLSDLKTARAQAYDLVLNGVEVGGGSLRIYQREIQQQVFEAIGLSPEEAQSKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEESIRDVIAFPKTQQARCLLTDAPSSVDAKQLKELHVASTYKPKS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAS1_PINST
Sequence: GLFIIDKEGVIQHSTINNEGVIQHSTINNLAIGRFGVLLADQGLALRSIPNGPSAL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.  May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf.
What are the official names of this protein?
Putative 2-Cys peroxiredoxin BAS1, PS13, Thiol-specific antioxidant protein, Thioredoxin-dependent peroxiredoxin BAS1.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: POA1_PHANO
Sequence: MDAQSTKDQGPEGADAGTLSFTYHIGDMFEDAPENCLLIHACNSQGHWGAGIAKAFKQKYPKAYTAHNKFCAKEHSKTQPVPTGSAQLLAPVDSGSQHWIGCLFTSAKYGKAKDKPDAIVKNTTASMSMLLELVRMADGEVSEIRMCKINSGKFGVPWEKTEEALKSIILQEGWREKIEIWEP
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.
Protein: SH2B2_HUMAN
Sequence: MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPPASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEAAPGRARAVENQYSFY
What is the function of this protein?
Adapter protein for several members of the tyrosine kinase receptor family.  Involved in multiple signaling pathways.  May be involved in coupling from immunoreceptor to Ras signaling.  Acts as a negative regulator of cytokine signaling in collaboration with CBL.  Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR.  Suppresses PDGF-induced mitogenesis.  May induce cytoskeletal reorganization via interaction with VAV3.
What are the official names of this protein?
SH2B adapter protein 2, Adapter protein with pleckstrin homology and Src homology 2 domains, SH2 and PH domain-containing adapter protein APS.
What is the protein family that this protein belongs to?
Belongs to the SH2B adapter family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Cytoplasmic before PDGF stimulation. After PDGF stimulation, localized at the cell membrane and peripheral region.
Protein: RIHC_SALDC
Sequence: MTASLHIILDTDPGIDDAAAIAAALFAPQLDLQLITTVAGNVSVEKTTRNALQLLHFWNSDIPLAQGAATPLLRPLRDAAYVHGESGMEGYDFVDHQRQPLAKPAFIAIRDVLMNAPEPMTLVAIGPLTNIALLLMHYPECACNIRRLVLMGGSAGRGNFTPNAEFNIAVDPEAAALVFRSGLEIVMCGLDVTNQAMLSPDFLNKLPALNRTGKMLHSLFNHYRSGSMRTGVRMHDLCAIAWLVRPELFTLQSCFVAVETQGQYTAGTTVVDIEGRLGQPANAQVALALDVDGFRQWVAEVFAYAP
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: DDIT4_RAT
Sequence: MPSLWDRFSSSSSSSSSSRTPAADRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLLSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC
What is the function of this protein?
Regulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1).  Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB.  Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage.  Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity.  Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes.  Required for mTORC1-mediated defense against viral protein synthesis and virus replication (By similarity).  Inhibits neuronal differentiation and neurite outgrowth mediated by NGF via its effect on mTORC1 activity.  Required for normal neuron migration during embryonic brain development.  Plays a role in neuronal cell death.
What are the official names of this protein?
DNA damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD-1.
What is the protein family that this protein belongs to?
Belongs to the DDIT4 family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol.
Protein: UVRC_VIBVU
Sequence: MTQIFDSVSFLKTVTHQPGVYRMYNAEAVVIYVGKAKDLKKRLSSYFRKKVDSEKTKALVSNIAKIDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYIFLSAHRHPRVSLHRGAKKRKGEYFGPYPDSGAVRETLHLIQKIFPVRQCEDTVYANRTRPCLMYQIGRCAGPCVSSVISDVDYAELVGYLRLFLQGKDNQVLELLVQKMEIASQQLKFEDAAKFRDQIQAIRRVQEQQYVSEDSQEDMDVLGFAQENGIACIHILMIRQGKVLGSRSHFPKIPQNTNAQEVFDSFLTQYYLSHNEARTIPSRIILNQELAADVEAIQLALSDVAGRKVQFHTSPSGSRGRYLKLSNTNALTAMTTKINHKMTINQRFKALRDVLAMDSIARMECFDISHTMGESTIASCVVFNSEGPVKQEYRRYNITGITGGDDYAAMGQALERRYAKQLDVEKIPDIIFIDGGKGQLNRAHEIIVQYWGDWPKRPVMIGIAKGVTRKPGLETLITVDGDEFHLPSDDPALHLIQHIRDESHNHAIAGHRAKRGKTRKTSALEGIEGVGPKRRQALLKYTGGLQELKRASVEEIAKVPGISHSLAEIIYQALKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_TREPA
Sequence: MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLTVSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDLRRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_RUMCH
Sequence: MQQYLDLCKHILNNGIKKEDRTGTGTISTFGYQMRFDLQKGFPLLTTKKLHLKSIIHELLWFISGNTNIKYLKDNGVSIWDEWADENGNLGPVYGHQWRSWDTADGRSIDQLKGVIDQIKNNPDSRRLIVSSWNVGEIEKMALPPCHCFYQFYVVNGTLSCMLYQRSADVFIGVPFNIASYALFTMMIAQSCGLRAGEFVHTLGDAHIYLNHVEQVKLQLSRDPRPLPKMNINPDIKDLFQFKYSDFTLTDYDPHPHIKGAVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP8_BTV13
Sequence: MLSGLIQRFEEEKMKHNQERVEELSLVHVDDTISQPPRYAPSAPMPSSMPTVALEILDKAMSNTTGATQTQKAEKAAFASYAEAFRDDVRLRQIKRHVNEQILPKLKSDLGGLKKKRAIIHMTLLIAAVVALLTSVCTLSSDMSVAFKLNGTSAEIPQWFKSLNPMLGVVNLGATFLMMVCAKSERSLNQQIDMIKKEVMKKQSYNDAVRMSFTEFSSVPLDGFELPLT
What is the function of this protein?
Facilitates viral particle release either by increasing plasma membrane permeability through a viroporin-like activity or by viral budding.
What are the official names of this protein?
Non-structural protein P8, Non-structural protein NS3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus NS3 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein. Host Golgi apparatus.
Protein: GATA_TREPA
Sequence: MDAHAITCASWNMLKAQLEAGAISSLQIVRAFRNVYEEDTRSASPLGALVEFFSDAEEHARTADNLRASCAQSTKTAGANGGSVSGKPLLGLPFAVKDNISVKGKHCTCGSKLLADYRAPYDATVVARLRAAGAIPLGRTNMDEFAMGSSTEYSVYGPTRNPRDRSRTSGGSSGGSAAAVAGGQAPFALGTETGGSVRLPAAYCGLYGLKPTYGLLSRYGVVAFGSSLDQIGFFATCIDDIALALSVTSGKDLYDSTSTCPPPATGRHAVSHHLAPFSAHECSILRAAVPRELVDAPGVHPDVSAQFQRFLTWLRAQNVQVEEVTLPALQAAVPVYYLVATAEAASNLARFDGIRYGQRGDTDALLENYYRAVRTSGFGPEVQRRIIVGNYVLSRHFSGDYYRTSVRVRSRIEQECTQLLCSYHFIVCPTAATGAFPLGERIHDPLAMYCSDLFTTFVNLARLPALSVPVGTSGTGLPIGIQIIGSQWQECAVLRLAKRWEEAPHV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS6_RICRS
Sequence: MSFYESVFIIRQDVSLNDIDKIVDDFAKIIKDNNGTIIKKEYWGLRTLAYKIGNNKKGHYYFLGLDITGNVKEELERKMKLNENIIRFLTIQADSISSEPSPILKNQSTENAPVIDVTINN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TRET1_AEDAE
Sequence: MFGNEMDDTRDPLQYGYQRVNTGEGSLSTSTTGTSLDTIVLDTNAEDLNSTPRVGAQRTFSPILETDDTNPFLDPPPPGQKSPPAVGEAKAKSKSSLKGSRVSFDQEDRFDETDEGFRKQREHFQKHKSHSTSEHKNQLIKELRHLLAADNRRQFQGKKHVSLDVQSSKVLEELLKASSSEDDFEGQRKQFQERKHKSLDARHISFKFEKEPTPSSSEEDFEPSTSLLKIDADITKPVIIDLKVNRAQSDQALTQFQKNLAHFQDLESSEDEDYISSRKHFQQAKSMSTDSRKSNKSIRFFEMEMGTKEENIRTAVPFVRQITEDGKPKLEVYRPTTNPIFIWTQVLAALSVSLGSMVVGFSSAYTSPALVSMKDRNITSFEVTDQSGSWVGGIMPLAGLAGGILGGPLIEYLGRKNTILATATPFIISWLLIACATHVAMVLVGRALSGFSVGVASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGKYMDWSGLAFLGAALPIPFLLLMFLIPETPRWYVSRGRDDRARKALQWLRGKKADVDPELKGIIKSHQDAERHASQSAMLDLMKKANLKPLLISLGLMFFQQLSGINAVIFYTVQIFQDAGSTIDENLCTIIVGVVNFIATFIATMLIDRLGRKMLLYISDVAMIITLMTLGGFFYVKNSGQDVSQVGWLPLAAFVIYVLGFSLGFGPIPWLMMGEILPGKIRGSAASVATAFNWSCTFIVTKTFADIINAIGTHGTFWMFGSICVIGLAFVIFYVPETQGKSLEDIERKMMGRVRRMSSVANIKPLSFNM
What is the function of this protein?
High-capacity facilitative transporter for trehalose.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph (By similarity).
What are the official names of this protein?
Facilitated trehalose transporter Tret1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HPAC_SALTY
Sequence: MQVDEQRLRFRDAMASLAAAVNIVTTAGHAGRCGITATAVCSVTDTPPSVMVCINANSAMNPVFQGNGRLCINVLNHEQELMARHFAGMTGMAMEERFHQPCWQNGPLGQPVLNGALAGLEGEISEVQTIGTHLVYLVAIKNIILSQDGHGLIYFKRRFHPVRLEMEAPV
What is the function of this protein?
Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH.  Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion (By similarity).
What are the official names of this protein?
4-hydroxyphenylacetate 3-monooxygenase reductase component, 4-HPA 3-monooxygenase small component, Flavin:NADH reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
Protein: SYY_CERSK
Sequence: MTYHPKSDFLRVMQERGYLADCTDKQALDEALSKGVVPAYIGYDATAASLHVGHLLNIMMLRWLQKTGHKPITLMGGGTTKVGDPSFRSEERPLLTPDKIDENIEGMRKVFARYLSYGEGATDALMLNNAEWLDHLNYLDFLRDIGRHFSVNRMLSFESVKSRLDREQSLSFLEFNYMILQAYDFLELFRRYGCRLQMGGSDQWGNIVNGIDLTRRVLEGEIFGLTSPLLTTSDGRKMGKSAGGAVWLNGEMLAPYDFWQFWRNTTDADVGRFLKLYTELPVEECDRLGALQGSEINAAKILLANEVTTLLHGRDAAEAAEATARAVFEEGGVGGALEVVELPATTLGEGLSVAHFLVAAGLVASGKEAKRLVAESGLRFNNEPVGDANAPVTAATVGEELKVSIGRKKHKLVRLS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCAB_ECODH
Sequence: MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASKHAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLTSRRNNRALSGVMINADAGLAIRGIRHVAAGLDL
What is the function of this protein?
Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively.
What are the official names of this protein?
3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase, 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase, 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase, CI-dihydrodiol dehydrogenase, Cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, Cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol dehydrogenase, PP-dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DXR_CAUVN
Sequence: MGALTSPRKVVVLGSTGSIGLSTLSLFEESGAPVQILALTAGRNVERLIEQARRWKPSLAVIEDESRLDDLRAGLAGTGVEAAAGADAVRDAAAMGADWVMSAIVGAAGLAPTVAAARTGAVIALANKESLVCAGPALLAIAKAAGGSVIPVDSEHSAIFQVLQSECAHRVSRLILTASGGPFRTWDKAAMARATPEQAIAHPNWSMGAKISVDSATMMNKGLEMIEASYLFATPEDRVDVVIHPQSVIHSLVEYVDGSTLAQLGPPDMRAPIACAFAWPDRLPWPAPRLDLAAYGQLTFESPDVERFPAIGIAREALRLGGGAPAAMNAANEVAVAAFLDRRIGFLDIAGAVAGTLERMNSLGDLSVAESDAVETAMLIDGSARRIAAEVVAQKRQRA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: COAA_SALEP
Sequence: MSIKEQSLMTPYLQFDRSQWAALRDSVPMTLTEDEIAQLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPEGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEELLQTWYINRFLKFREGAFTDPDSYFHNYAKLSKEEAVNTATSLWKEINWLNLKQNILPTRERASLIMTKSANHAVEQVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYEA_YEREN
Sequence: MAYDLSEFMGDIVALVDKRWAGIHDIEHLANAFSLPTPEIKVRFYQDLKRMFRLFPLGVFSDEEQRQNLLQMCQNAIDMAIESEEEELSELD
What is the function of this protein?
Involved in the control of Yop release.
What are the official names of this protein?
Protein TyeA.
What is the protein family that this protein belongs to?
Belongs to the TyeA family.
Protein: GLMU_HAEIN
Sequence: MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN11_MOUSE
Sequence: MLNYSDISWAEKGMVATINHSRLKDKGVGQHQNAYNYKNQNYEDLRAECLRKGELFEDPFFPAEPRSIGVKNLGPNSEHMQNIYWQRPKDIIHNPQFITNDFSPTDICQGILGDCWLLAAIGSLTTCPKLLYRVVPRNQSFKKNYAGIFHFQLWQFGHWLNVVVDDRLPTRNNKLVFVHASHRQDFWSALLEKAYAKLIGSYGALSGGSTLEGLEDFTGGVAQCIPLQKPPGNMLRLLKKALEKSSLMGCSIEVTDNSEVETMTHNMLVRGHAYAVTGLEDVYYRDKLETLIRIQNPWGRVEWNGAWSDKATEWEEVSPDVRVQLLHKKDDGDFWMSYEDFMSNFTLLEICNLTPDALNTWDYKSRWHSTFYEGSWRRGSTAGGCRNHPETFWSNPQFKISLPEVDDPEDDSEKNEMVCTCLVALMQKNWRHAREGPQLLTIGFVIFSVPKEFQNLRDIHLKKDFFLKYRDHGFSEIFINSREVNSHLRLPPGEYVIIPSTYEPHKDADFLLRVFTEKHSETWLLDDANRFEHLQEETVTDKDLDKDSLQLFKIMANEDGEVDMYALHKLLNRMTAKLRNFKTKGFSLEVCRRMINLLDKDGSGKLELHEFQVLWKKIKKWTEIFKECDEDRSGNLNSYEMRLAIEKAGIKMNNRVTEVVVARYSDNMIVDFDSFLNCFLRLKAMFAFFLSMDTKKTGSICLDINQWLQITMWG
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
What are the official names of this protein?
Calpain-11, Calcium-activated neutral proteinase 11, CANP 11.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome.