PharMolix/UniProtQA huggingface dataset:
Protein: TIM54_YEAST
Sequence: MSSESGKPIAKPIRKPGYTNPALKALGIPALRLPSRNWMIFWSVLTVSIGGIAYDKYKQRQILSHATDLVKPLAEESMEVDKVPRKITVFIAPPPNDYLESSLKVWRRYVKPVLYYAGLDYELVQEDRQGIIRTNVANRIRELRKEILASTDGQPVKEPNQTVAKPSGSSTSKISSLLPFNKIIQDPAEEDDSFDPEIGKKFKENFDWRNVIGIFYTMPKPKHIISEDALTKDPILSGGVICLGRGAYKEYIAGIHEGLLGPIEKTEKTGSTEPKMTGVVEANQIESKVSESGATELVDAEKETALEEAKVQDDLKVDEENSSEDSQKFLKPFISSDQYPDLQIASELQTPNGEFIRNPNTNIPLLINQPLLVIPIPNLIGFTTIPRRIHRFYQKRFYVEDVCSSVVNCVRQTRIRPFDIAKDIDLAKDEEKDWPQNWVKQGKEKNSEWTQELVCDPRITKHMFVYEKPPKEEPESDI
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force.  Its precise function within the TIM22 complex is unclear.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=Import into inner membrane protein requires TOM70 function.
Protein: RER1_SACPS
Sequence: MDYDSPDPMNGASSNALIAKMNSAKLLYQHYLDKVTPHAKQRWAVLGGLLCLFMVRITMAEGWYVICYGLGLFLLNQFLAFLTPKFDMSLQQDEENNELEAGEKSEEFRPFIRRLPEFKFWYNSIRATVISLVLSLFSIFDIPVFWPILLMYFVLLFFLTMRRQIQHMMKYRYIPLDIGKKKYSHPSN
What is the function of this protein?
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.  Required for correct localization of SEC12, SEC71 and SEC63 in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Protein RER1, Retention of ER proteins 1.
What is the protein family that this protein belongs to?
Belongs to the RER1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NCPP_PROMH
Sequence: MYHVIAATTNPAKINAIKLAFEQVFGKDTFDIEDINVDSRVPQQPIGNTETRTGARQRVMAARQVRPEADFWVGVEAGIEDDMTFAWIVIEHEQIRGESRSASLMLPEQILKGVREGRELGDEMAFLTKIDNIKQKGGAIGYFTDGLLSRTSVYQQAIVLALVPVTHDIYKQLNKKDDE
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: RS5_CLOBH
Sequence: MRIDPSTLNLKEKVVHINRVAKVVKGGRNFRFSVLVVVGDEAGHVGVGTGKSIEIPEAIRKAIEDAKKNIVEVKTVGTTVPHDIIGKFGKGEVLIMTAKEGTGVIAGGPVRAVLELAGLKDVRAKSKGSNNPTNMVNATIDGLARLRTVEDIAKLRGKTVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y453_STRZJ
Sequence: MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVINGVFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGTLLLLAYAGTQTRAGSLKKD
What are the official names of this protein?
UPF0397 protein SPJ_0453.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDKA1_BOVIN
Sequence: MANSERTFIAIKPDGVQRGLIGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIALWFHPEELVNYKSCAQNWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities.  Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression.  Required for neural development including neural patterning and cell fate determination.
What are the official names of this protein?
Nucleoside diphosphate kinase A 1, NDK A 1, NDP kinase A 1, Nucleoside diphosphate kinase NBR-A, NDK NBR-A.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus.
Protein: RLMM_SODGM
Sequence: MNNVILYCRPGFEKECSAEVTEKAAAREIFGFARVKDNSGYVVFVCYQHEEADRLVRVLPLRSLIFARQMILVGELLRDLPAEDRITQIAGMLTGAVAGAGEVRVEVPDTNESKELMKFCRKLTVPLRAALRAQRILKGEEHRSPQVIHVLFIAPGCCYAGYSYRDNHSPFYMGIPRLRFPPDAPSRSMLKLEEAFHVFIPADEWDERLGSGMYAVDLGACPGGWTYQLVKRSMMVHAVDNGTMDEALMATGQVIHHRADGFRFEPPRNNVYWLVCDMVEKPSRVAQLAADWLVKGWCREAIFNLKLPMKKRYEEVSQNLRLLIDHLQVNGVHGEVHAKQLYHDREEVTVHARRFWSAVPGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_SACS2
Sequence: MKEKDNFEMIINLRKIKTGKRTGRSKRAVKFIKKVVARHFNAEKVIIDPLLAKSISKNGNDKIVSKIRVVVSKIEEKIYLVRLAIKSR
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: PYRB_CHLL3
Sequence: MAALQHLTGLCGMSAGTLSGLLDKTEGFKKELTAPAPSFSPSLQGRRIALVFFENSTRTRFSFELAARNLGASTLGFSASTSSVTKGETLSDTIKNLEAMQVDAFVLRHPSSGSAEFISGITKKPVVNAGDGANEHPTQALLDMFTLREHFGTLKAIKVAIIGDVLHSRVARSNIHGLLTMGAEVGLCSPVTLLPPDSEKLGVSLFTDLDQALGWADAALVLRLQLERATGGYLPSLQEYSVHYGLTDERLERTARHLLVLHPGPINREIEISNRVADRIQPPGYSKSMLLEQVTNGVAVRMAVLQTLLADTP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PETL_CUCSA
Sequence: MLTITSYFGFLLAVLTITSALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TBCA_RAT
Sequence: MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMKAEDGENYAIKKQAEILQESRMMIPDCQRRLEAAYTDLRQILESEKDLEEAEEYKEARIVLDSVKLEA
What is the function of this protein?
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA.
What is the protein family that this protein belongs to?
Belongs to the TBCA family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL2_ECOSE
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SURE_CHESB
Sequence: MRILLTNDDGIHAEGLAVLERVARTLSDDVWVVAPETDQSGFAHSLSLSEPLRMRKIDDRHYALRGTPTDCVIMGVRKVMDRPPDLILSGVNSGTNLADDVTYSGTVAGAMEGTLLGIRSIAFSLGYSFVEDIRVVQWETAEVLGPALLKKLVGASLPQGVFLNVNFPRCTPEAVKGTLVTSQGKLVHGLSVEERRDGRGFPYYWLRFGRQESEIRAGTDQAAIRDGYVSVTPLHLDLTAHAVRDRLAKALA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS2_STRCO
Sequence: MPLLTRITGPRDLDRLSLEELTQLAEEIRTFLVDAVSKTGGHLGPNLGVVELTLALHRVFESPKDKVLWDTGHQSYVHKLLTGRQDFSKLKMKGGLSGYPSQGESEHDVIENSHASTVLGWADGIAKANQVMERDDHVVAVIGDGALTGGMAWEALNNIAAAKDRPLVIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLARTKEVLERTPVVGRPLYDTLHGAKKGLKDFIAPQGMFEDLGLKYVGPIDGHDLEALESALTRAKRFGGPVIVHCLTEKGRGYQPALQDEADRFHAVGKIHPDTGLPISTSGADWTSVFGDEMLKLGKEREDVVAITAAMLQPVGLDKFAKAFPDRVYDVGIAEQHGAVSAAGLAHGGVHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGVTGTDGASHNGMWDMSILQVVPGLRLAAPRDADQVRAQLREAVVVDDAPTVVRFSKGAVGPAVPAVGRVGGMDVLRAPGTGTPDVLLVSVGALAPMCLEVADLLNKQGISTTVVDPRWVKPVDEAMAPLAERHRVVVTVEDNSRVGGVGSAVAQALRDAGVDVPLRDFGIPPRFLDHASRAEVLAEIGLTAPDIARQVTGLVARLDGRYDRAGAEVDQVEAARD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 2, 1-deoxyxylulose-5-phosphate synthase 2, DXP synthase 2, DXPS 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y2968_ENT38
Sequence: MDWLSKYWWILVLVFLVGVLLNVIKDLKRVDHKKFLANKPELPPHRDFNDKWDDDDNWPKKDQKK
What are the official names of this protein?
UPF0370 protein Ent638_2968.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: APOD_RAT
Sequence: MATMLLLLATLAGLFTTTEGQSFHLGKCPSPPVQENFDVKKYLGRWYEIEKIPVSFEKGNCIQANYSLMENGNIKVLNKELRPDGTLNQVEGEAKQSNMSEPAKLEVQFFSLMPPAPYWILATDYESYALVYSCTTFFWFFHVDYVWILGRNPYLPPETITYLKYILTSNDIDIAKITTKDQANCPDFL
What is the function of this protein?
APOD occurs in the macromolecular complex with lecithin-transport and binding of bilin.  Appears to be able to transport a variety of ligands in a number of different contexts.
What are the official names of this protein?
Apolipoprotein D, Apo-D, ApoD.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOC_VIBA3
Sequence: MSDLKAAALRALKLMDLTTLNDDDTTEKVVALCHDAKTAVGNTAAICIYPRFIPAAKKALREQGTPEVRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALIADNEEVGFELVKQCKAACGDITLKVIIETGELKEEALIKKASQICIEAGADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADELLGAEWADNMHYRFGASSLLTNLLNTLEVTDETADPAAY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SOLM1
Sequence: MSQTQSLAVKTRAGLGKGACRKLRADDMVPGVYYDAKGVNVPVMVEHLPLQKLYSKIASSHVFDLQIEGETKPALVWKVEHHPTKPRITHVDFYGVDLTKEIQVRVPVEVVGKSKGQVKGGQLEIHREFIEVLCLPLVIPDKIVLDITNVDINESILIADVVLPEGVKAVYDNNYAVIGVLASAAEAAGEGA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SYK_RICRO
Sequence: MSEIWEDAIKSNAWPFVEAKKILDSLNGQIPEKGYVLFETGYGPSGLPHIGTFGENARMVMVQKAFEQLSDIPTKLICFSDDMDGLRKVPSNIPNPEMVAQYMDMPLTSIPDTFGECESYGHYMNAKLRSFLDKFGFEYEFYSSTNCYKAGMFDEMLIMVLEKYDEIMELMLPTFREERKATYSPFMPICPKTGKVLQVPIEKWDAKAGTVTYKDKAGNYIEVPVTGGHCKLQWKPDFGMRWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISIDDWLKYAPVESMALFMYQNPTRAKRLFFDVIPKNVDEYITFNQKYHLEEDRAKRVANPVYHIHHGNVPKIETFGITYSLLLNLTSVCNPSDKSVLWGFISKYEPQATPNTNPYLDHLAEFAIRYYNDFIKAHKSYLSPSEKHKVILQDILDMLSDIADQTEAEAIQKAIYDIGMKAGYANLRDYFKDLYQILLGQNEGPRLGTFIKLYGVQEMKKLVEGQL
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_BORPD
Sequence: MTAATLAQLRVDNSFAALPAAFYTRLAPQPLTAPRLLHANEQAAALIGLSADALRSDEFLRVFSGQQPLPGGQTLAAVYSGHQFGVWAGQLGDGRAHLLGEVAGPDGNWELQLKGAGMTPYSRMGDGRAVLRSSVREYLASEAMHGLGIPTTRSLALVVSDDPVMRETVETAAIVTRMSPSFVRFGSFEHWSSRRQPDELRILADYVIDKFYPECREPRPGEAPGPDGALLRMLAEVTRRTAELMAGWQAVGFCHGVMNTDNMSILGLTLDYGPYGFMDAFRLDHICNHSDSEGRYAWNRQPSVALWNLYRLGGSLHALVPDVEALRAVLDSYEVIFTRAFHQRMAAKLGLREWRADDEPLLDDLLRLMHDNRADFTLTFRRLADAVRGRPQGLQDLFIDRDAALAWFERLAARHAQEGAGNDAQARAAGMDAVNPLYVLRNHLAEQAIRAAKAGDAGEIDTLLALLRDPCVEQPGRDAYAALPPDWAGGIEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL14_PYRFU
Sequence: MAKKGAGATRGVSAVRPTRALPVGAYLTVADNSGAKVIQIIGVVEYHGTRRRLASAGVGDMVVATVKKGRPDMRHQVVRAVIIRQRKEYRRLDGMRVKFEDNAAVIVTPEGVPRGTEIRGPVAREAAERWVRIGSIASIIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14, Large ribosomal subunit protein uL14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: F110C_RAT
Sequence: MRALPTLDSLARTRPSLGDSRAAEGTLTRQPANKSAVERLAADRAKYVRSTLGSSRGPVSENRVPEAPGVQHRNPIPSTLAPAPVARRAVARKPLRPDSLVIYRQKCEFVRGSDADSSRVGLMKKFFQGSGKDKMSVTPETTRVADEYKTKETEATWTKASQAAAAKPASMLPPPAPVVAMESPALPFEVAPRVPVRRSGVELRASRSKGLQRSQSDLSSRYSTARAESDTFFQYCGLDPEVVESLGRENFSAASDCVTPKMRSVSMATSDSSFSRHSEDGLQEEELLEQVPSTTSVVERNARIIKWLFTCKKAKETPSQKLQEPA
What is the function of this protein?
May play a role in microtubule organization.  May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
What are the official names of this protein?
Protein FAM110C.
What is the protein family that this protein belongs to?
Belongs to the FAM110 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Note=Colocalizes with microtubules during interphase. Detected at the mitotic spindle poles. Colocalizes with AKT1 at the cell cortex.
Protein: LEUD_BACCQ
Sequence: MEPFRIHKGTAAVLMNNNIDTDQIIPKQYLKRIERTGFGKFLFDEWRYDNERHENPNFPLNAPDRKGASILITGDNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKEMREKLAKTDAREQIEVDLENEVITTSTHRFHFTIEKMWKEKLLNGLDEISITMQYEQEIKEYERRIAVY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: ALN_YEAST
Sequence: MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEIHTLENVSPCTILPGLVDSHVHLNEPGRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHNLPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELPKAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCCPPIRSESNRQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQGCSLVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.  Involved in the utilization of purines as secondary nitrogen sources, when primary sources are limiting.
What are the official names of this protein?
Allantoinase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: MOAC1_MYCTU
Sequence: MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLCHPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRRSASDLACQSR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) (By similarity).  Probably plays a role in host phagosome maturation arrest (PubMed:20844580).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase 1, Molybdenum cofactor biosynthesis protein C 1.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ELCG_PHANO
Sequence: MACNILNFLTGLLSLSSTLPSTYFPSCIKPSNSHVSQNPVRFEVHLTPGRANPTGAGFRDVILVNGTFTGPTLRLSRGDNVEFLVRNHLREDTAVHFHGITQSLSPWADGTPGIAQRPIRPGAAYLYRWRADESGVFFYHAHSRGQLMDGMYGAIVIERGEDEPSPFHMISHEASDWELMREAEREVQTLMISDWSQFSFGEVMGVEREANIDFTCMDAIVVNGAGSEYCLERELLNEYTNPLVKFILSHTDEKEITDKGCVPPLRLFQGNYSLHLDTLPPEAFRKCIPGVGGGANHTVTVHSSNRWAALTFINPGGLYPLKVTIDNHPMHVFAVDGHYIYPQIVDQILVNNGERYSVFVKLDQEVGRYTIRIANDLLGQVLGGFAALSYNGVMDDPPHPKPLMNYAGGSLVKNIRVFDEFNTRPYPPKPPASVADRTHKFMVRKLAQPHGAYEWTMSGIEGLNMTTEDVASPFLFQDPSQIETSELMLTTKKNEWVDLIIEVEGPFAQSHPMHKHGNKAFIVGRGVGFFPWATVEEAEKHLPRGTFNFIDPPYKDTFKTLEGVNNNAWLALRYHANSPGAWLFHCHIQTHLAGGMGVVILDGVDEWPELPEAYAEWNGFEAPV
What is the function of this protein?
Multicopper oxidase; part of the gene cluster that mediates the biosynthesis of elsinochrome C, a perelyenequinone phytotoxin structurally similar to cercosporin (PubMed:28251756, PubMed:30809363).  The first step of elsinochrome C biosynthesis is performed by the polyketide synthase elcA which catalyzes the formation of nor-toralactone (PubMed:28251756, PubMed:30809363).  The starter unit acyltransferase (SAT) domain of elcA initiates polyketide extension by the selective utilization of acetyl-CoA, which is elongated to the heptaketide in the beta-ketoacyl synthase (KS) domain by successive condensations with six malonyl units introduced by the malonyl acyltransferase (MAT) domain (By similarity).  The product template (PT) domain catalyzes C4-C9 and C2-C11 aldol cyclizations and dehydrations to a trihydroxynaphthalene, which is thought to be delivered to the thioesterase (TE) domain for product release (By similarity).  The bifunctional enzyme elcB then methylates nor-toralactone to toralactone before conducting an unusual oxidative aromatic ring opening (PubMed:28251756, PubMed:30809363).  The next step in perylenequinone biosynthesis is an O-methylation at the nascent OH-6 of the elcB product performed by the O-methyltransferase elcD (PubMed:30809363).  The oxidative coupling of the two monomeric naphthol units in perylenequinone biosynthesis is catalyzed by the FAD-dependent monooxygenase elcE and the multicopper oxidase elcG (PubMed:30809363).  ElcG might catalyze the first intermolecular coupling in a regio- and stereo-selective manner via a phenol radical coupling mechanism and the elcE could forge the second C-C bond intramolecularly via a hydride transfer mechanism (PubMed:30809363).  The fasciclin domain-containing protein elcF might also play a role duting this step (Probable).  The last piece of the puzzle in the biosynthesis of elsinochrome C is the additional annulation by enolate coupling to afford the dihydrobenzo(ghi)perylenequinone system, catalyzed by the FAD-dependent monooxygenase elcH (PubMed:30809363).
What are the official names of this protein?
Multicopper oxidase elcG, Elsinochrome C biosynthesis cluster protein G, Laccase elcG.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: YF66_SCHPO
Sequence: MTFYYIRILRLQEKLEESFKYALRVVFTITSDLGEVSYPQDATVRVEALDRQQSHSRITISKQCVSWIGNGHAAETTLYFPASHQQIQLTLHLENQNSIVDSIHINADTVLPVWSEAFSPKSTLPNMVWRYIQGPEKKSPNDGLWFLEQMGNSIAKHLWDAGVVFSKKILSDDWHYSFSNRKDINVLELGSGCGIVGISIASKYPRALVSMTDTEDAIEFMEKNVEKNKSAMSNNITSDILVWGHDIPRKFRRHWDYIVMSDVMYNESSFSDLEASLQELMDKNTKLYIAYKKRHDNEKTFMSNILGWLDLVYEERGPITIYILQKK
What are the official names of this protein?
UPF0665 family protein C23C4.06c.
What is the protein family that this protein belongs to?
Belongs to the UPF0665 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YQGF_STRE4
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDRLAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_BRASB
Sequence: MAKKSSVEKNNRRKRMAKNAAPKRARLKAIIADKTKPMEERFAATLKLAEMPRNSSATRIRNRCELTGRPRSNYRKNKLSRIALRELGSKGLVPGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS17_LEGPH
Sequence: MSTNSESNARTMIGKVVSDKMDKTIVVMIERTVKHPKYGKIMKRRTKLHAHDENQVCRVGNTVKIRESRPLSKTKSWVLVEVIS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DEF_MYCPN
Sequence: MTKILPVSTISIFRIILILPQINMELLPTKAWLVLDDVKEINEPTKPVQFPLDQASLDCIAKMMAYVDASYNGDAEKYGIIPGIGIAANQIGYWKQMFYIHLMDGGVEHKCLLINPKIINLSANKSFLKSGEGCLSVPKMHQGYVIRHEWITITGFDWLQQKEITITATGLFGMCLQHEFDHLQGRFYYHRINPLNPLFTNKEWKVINPALPSDSE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.