PharMolix/UniProtQA huggingface dataset:
Protein: EFTS_SOLUE
Sequence: MAEITASLVKQLRERTGAGMMECKSALVEAKGDLTEGEVVLRKRGIASAGKKASRATKQGLIGTYIHHGGQLGVMVEVNCESDFVARTDDFQELVHDIAMHIAAADPKFIRKEDVTEDVIEKEKDIHKARALAEGKPEKMLDKITEGRMSKFYEEICLLEQPFVKEATLTVGQLVKTKIAKLGENISVARFVRFKVGDAQGSDSGSETPAAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_ECOLI
Sequence: MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHNEKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAGSGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGFAPPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGFGGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQYGINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQLRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLSTLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTTMRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYRGTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNEERLELWTLNQELAKK
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: NU2M_GARCR
Sequence: MNPIIFFMIMLTIILGTTIVMTSSHWLTVWMGFEMNMLAIIPMLMKNHHPRSTEAATKYFLTQATASMLLLLAITINLMSSGQWTVTNMINPTSSIILTIALAMKLGLAPFHFWVPEVTQGTPLSSGLILLTWQKLAPLSILLTMSPIINLDLLLMMGLLSVMIGGWGGLNQTQLRKIMAYSSIAHMGWMVTILIYNPTLTMLNLTIYIMMTLTMFMLLITTSTTTTLSLSHAWNKMPLITTMMLTTLLSMGGLPPLTGFMPKWMILQELTKNNSIILPTFMAITALLNLYFYMRLTYSTSLTMFPTTNATKIKWPFMTTKQMTYLSPLMVISTMTLPLTPMMMILH
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYY_MESH7
Sequence: MSYIEKQEFLAELKTRNILKDISSPEKFFNLKPDQGIYIGFDPTATSLHLGNYISISLLKRLQKIGIKVLAVIGGATGMIGDPSFSSKERKLLDFKTLNANKEKIKKQLESFGLPVFDNFEIYKNMNILDFLRDVGKNINISYLLAKESVASRIEVGLSFTEFSYQLIQGWDFKFLAENYRIIGQAGGSDQWGNMVTGLDFIKKSNLDQKDEAFVFTTNLLTDENGQKFGKSLGKPIWLDPEMYSPFHLYQFLLNQSDEQAEKIMLWLSFLDLKVINELIFKHKKDKKQRILQYNLAKQVVFDIHGDKGLEIAKKITKILFEKLDYTKITFNDKLELKKIIPYFKVSFFNANQIIDLGIFKSKRELNEFISHKALEINGSKISNISDITEELKDKSNLFLLRKGKKYFFMIELI
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNJA3_HUMAN
Sequence: MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLSVPAFASSLTSCGPRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGSAGFDPGASGSQHSYWKGGPTVDPEELFRKIFGEFSSSSFGDFQTVFDQPQEYFMELTFNQAAKGVNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISPCVVCRGAGQAKQKKRVMIPVPAGVEDGQTVRMPVGKREIFITFRVQKSPVFRRDGADIHSDLFISIAQALLGGTARAQGLYETINVTIPPGTQTDQKIRMGGKGIPRINSYGYGDHYIHIKIRVPKRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSGGSTMDSSAGSKARREAGEDEEGFLSKLKKMFTS
What is the function of this protein?
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix.  Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation.  Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis.  Can modulate IFN-gamma-mediated transcriptional activity.  Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
What are the official names of this protein?
DnaJ homolog subfamily A member 3, mitochondrial, DnaJ protein Tid-1, hTid-1, Hepatocellular carcinoma-associated antigen 57, Tumorous imaginal discs protein Tid56 homolog.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cytoplasm, cytosol. Postsynaptic cell membrane; Peripheral membrane protein. Note=Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK.
Protein: GIC2_YEAST
Sequence: MTSASITNTGNETMNLPQMRSIWLDEDEEAEKLYGLQAQQFMGSDDEENLGITFINSDKPVLSNKKNIELPPLSPNSHPSCHHRRSNSNSAKSKESSSSSSSANKTNHKKVFLKLNLLKKKLLGAQPDIRGKGISTPFDFQHISHADTRNGFQDEQLQEPSSLSTEIKDDYTSSSSKRDSKSLNKAFVTERIPANRESKLISRSHENKTSRLSVARSISVTSSNYSKNTQGNNHSINGRVVSTSTMATSIFEYSPNASPKQFKNKSHALGHRYTNSTDSSESSLDFLKNYNFPTLLEDKPILDFLPRSQRSSAYRSLLETPNSNKDSAKAFFPSRQSPLPKRRNSIATPSPQSKFSYSDSPVNHRKSFDDVLYSFNQLEPLQT
What is the function of this protein?
Required for cell size and shape control, bud site selection, bud emergence, actin cytoskeletal organization, mitotic spindle orientation/positioning, and mating projection formation in response to mating pheromone.
What are the official names of this protein?
GTPase-interacting component 2.
What is the protein family that this protein belongs to?
Belongs to the BORG/CEP family.
What are the subcellular locations of this protein?
Bud neck. Bud tip. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Protein: THIC_PROM3
Sequence: MRASWVAARKGQANVSQLHFARQGVVTQEMDYVARRENLPESLVMEEVARGRMIIPANINHANLEPMAIGIASSCKVNANIGASPNASDVAEELKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPLVKGRLTGIVSRGGGILAQWMLYHHRQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCQHDASDAAQLAELKTLGELTKRAWAHDVQVMVEGPGHVPMDQIEFNVRKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKQYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDEDLEGLEKSLKSKGKAELPA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PA2A2_PROMU
Sequence: MRTLWIVAVLLLGVEGNLWQFREMIKEATGKEPLTTYLFYACYCGWGGRGEPKDATDRCCFVHDCCYGKLTACSPKLDMYTYSQKNEDIVCGGDDPCKKEICECDKAAAICFLNNLGTYNEEYNNYRKSRCIEESPKC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that displays edema-inducing activities, exhibits indirect hemolytic activity, and inhibits ADP-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIS1_ARTBC
Sequence: MSPILTNRQAEELHKSIIAYLTANNLLDTANTLRAELNLNEDAFDPATAKKYETLLEKKWTSVVRLQKKIMDLESRMSAMQAELDNATPTSLSKRNKDPASWIPTAPARHALESHRDTINSVAFHPIFSSVASASDDCTIKIWDWELGELERTIKGHTRAVVDVDFGGPRGGILLASCSSDLSIKLWDPSNEYKNIRTLVGHDHSVSAVRFIPLGASGAPSSGNLLASASRDKSLKIWDANTGYCLRTLQGHTAWVRDVFPSPDGRFLLSTGDDSTARLWDISVSNPETKVTMFGHDHFNECCAIAPSTSYQYLSPLTGLKKPPPASSTAEFMATGSRDKKIKIWDARGTCLLTLAGHDNWIRALAFHPGGKYLFSVSDDRTLRCWDLSQEGKCIKVMRDAHERFITCLRWAPSIFKDAPTGNGASDGKNGDIKKSDSPEVQIRCVIATGGVDMKLRIFAN
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: DAPF_RALPJ
Sequence: MKLHFTKMHGAGNDFVVLDGIQTPIDFTPEQWAAIADRHFGVGADQLLLVERSTRPDVDFRYRIFNHDGGEVEHCGNGARCFVKFVTDRGLTDKRTVRVEVMNGIATLTMQDDGQVTVDMGAPVFEAARLPFLPEGLPTRTQGDDTQHALQINGRTEWLSTVSMGNPHAVQIVDDTEAFPVLEDGPLIESHAVFPRRVNAGFMQIVDRHSVRLRVYERGAGETLACGTGACAAVVAGIRRGLLDSPVKVATHGGDLTIAWAGDGQPVMMTGPATTVFEGTLDLDALKLTAAH
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOM22_HUMAN
Sequence: MAAAVAAAGAGEPQSPDELLPKGDAEKPEEELEEDDDEELDETLSERLWGLTEMFPERVRSAAGATFDLSLFVAQKMYRFSRAALWIGTTSFMILVLPVVFETEKLQMEQQQQLQQRQILLGPNTGLSGGMPGALPSLPGKI
What is the function of this protein?
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (PubMed:10982837).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM22 homolog, hTom22, 1C9-2, Translocase of outer membrane 22 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom22 family.
Protein: ALR_SALAI
Sequence: MWQAEVRVDLDAIRENVSWLRSGSAAELMAVVKGDGYGHGMVPAALAALDGGADWLGVCTLDEALTLRREGITAPILAWLLAPGLPLHEGVAAGIDLGAASVAQLDEMVQAGRTAGRPARLHLKIDTGLSRGGATVSDWPGLLTAAAKAQADGTVEVVGVWSHFVYADAPGHPTTDRQLAVFHEGLDMVEKAGLRPRYRHLANSAATLTRPDAHFDLVRPGLAVYGLSPVAGESFGLRPAMTARARVMLTKQVPAGAGVSYGHTYTTERDSTLAVIPLGYADGVPRSASNSGPVHLGGVRRTISGRVCMDQFVLDCGDDPVAPGDVAVLFGSGRNGEPTADDWAEAVGTINYEIVTRFGSTRVPRSYDGERP
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RS17_SYNE7
Sequence: MAVKERVGVVVSDKMDKTVVVAIEDRTAHPKYGKIVVRTKRYKAHDEDNRAKTGDRVRIQETRPLSRTKRWTVAEILESVGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RECR_BRUAB
Sequence: MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRDPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: COAD_ANADF
Sequence: MPRRTAIYPGSFDPLTNGHLAIIQRGLKVFDRLIVAVANNPQKSPLFTAEERKALISEAVGNDPRVEVDSFNALLVDYVRTKGVYTVIRGLRAVSDFEYEFQLANMNRKLLPEFEAVFVMTGEDYFFVSAQLVREVATFGGDVTGLVPPNVAQELRRKLGTPAHR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHB1_RHORH
Sequence: MDGIHDTGGMTGYGPVPYQKDEPFFHYEWEGRTLSILTWMHLKGISWWDKSRFFRESMGNENYVNEIRNSYYTHWLSAAERILVADKIITEEERKHRVQEILEGRYTDRKPSRKFDPAQIEKAIERLHEPHSLALPGAEPSFSLGDKIKVKSMNPLGHTRCPKYVRNKIGEIVAYHGCQIYPESSSAGLGDDPRPLYTVAFSAQELWGDDGNGKDVVCVDLWEPYLISA
What is the function of this protein?
NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.
What are the official names of this protein?
High-molecular weight cobalt-containing nitrile hydratase subunit beta, H-NHase, H-nitrilase.
What is the protein family that this protein belongs to?
Belongs to the nitrile hydratase subunit beta family.
Protein: PRMA_THIDA
Sequence: MPWQSVRILVDSVQAEPLSDALMEAGALSVSLEDADAGTVDETPLFGEPDHPSAELWPHSIAVVLLEADADVAETLRAAAAQAGVAAPLDYTVETVAEQDWVRLTQSQFDPIPISARLWIVPTWHEAPDSRALNLKLDPGLAFGTGSHPTTRLCLRWLDANLRGGETLLDYGCGSGILAIAAAKLGARRVEGVDIDPQAVSASRDNAALNEVDAHFGLPGELAAGEYDVVVANILTNPLKAMAPLLAGRVRSGGSLVLSGILAEQAEDVMAVYRPWFVFDAPASDEGWVRLVGVKR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SLS_DENPO
Sequence: RICYIHKASLPRATKTCVENTCYKMFIRTQREYISERGCGCPTAMWPYQTECCKGDRCNK
What is the function of this protein?
This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions.
What are the official names of this protein?
Calciseptin, Calciseptine, CaS, L-type calcium channel blocker.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. L-type calcium blocker sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HMUV_VIBA7
Sequence: MSTTAAIQASNISVTFGHRTILDKIDIEIFSGQVTALLGPNGAGKSTLLKILSGEISSTGKMAYFGVPQALWQPNELAKHLAILPQQSTLSFPFIAQEVVELGALPLNLSHQQVSEVALHYMQQTDISDRANNLYPALSGGEKQRLHLARVLTQLHHSGDKKILMLDEPTSALDLAHQHNTLRIARSLAHQEQCAVVVVLHDLNLAAQYADRMVMLHNGKLVCDAPPWEALNAERIEQVYGYSSLVAAHPTMDFPMVYPI
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACP_CAUVC
Sequence: MSDILERVRKIVIEHLDADPEKVTEKASFIDDLGADSLDNVELVMAFEEEFDIEIPDDAAEHIQTVGDAVKFITEKTA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VHCD_METVO
Sequence: MAENWEPKIVGFCCNWCTYGGADTAGVGRMQYPPSIRIIRVMCSGRIEPSFILKAFKEGADGVFIGGCHPGDCHYDAGNYKWQRRVMMLYDMLDELGIEKERVMHEWISASEGEKFQIAMNDIYDKIKAMGPCTLKENTGKIDE
What are the official names of this protein?
F420-non-reducing hydrogenase vhc iron-sulfur subunit D.
What is the protein family that this protein belongs to?
Belongs to the MvhD/VhuD family.
Protein: UBIA_YERPS
Sequence: MKGSTVHTKWQAYCRLMRIDKPIGSLLLLWPTLWALWLAGRGIPEAKILVVFVLGVFFMRAAGCVVNDYADRHIDGFVKRTASRPLPSGTISEKESKILFVVLILLSFGLVLTLNSMTIWLSLAALALAWIYPFMKRVTHLPQVVLGAAFGWSIPMGFAAVSESLPLVCWLLLLANICWTVAYDTQYAMVDRDDDLRIGVKSTAILFGQHDKLIIGLLQLATLLLMVAIGWLMNLGGAFYWSILLAGALFTHQQKMIAQREREPCFRAFLNNNYVGLVLFLGILISYW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MB212_DANRE
Sequence: MIATQAKLVYQLNKYYNERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGMEVIAPNEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFAEAENRLLMSGCRKKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALETAAKQTWRLAREILTNAKSLDKL
What is the function of this protein?
Required for eye morphogenesis.  May promote the survival of proliferating retinal progenitor cells.
What are the official names of this protein?
Protein mab-21-like 2.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly localizes to the nucleus, with some cytoplasmic localization (PubMed:25719200).
Protein: PNP_CORGB
Sequence: MSDVKYFEDTEFGLIEAVATIDNGDFGTRTIRFETGQLARQADGAVTTYLDDDTMLLATTTASNQPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTEAILACRLIDRPLRPTFVKGLRNEVQIVVTVMSMNPEDYYDVVAINGASAATRISGLPVSGAVGGVRMALVVDEKHPEGQWVAFPTHAQHEQSVFEIVVAGRLVERKRGNKTFSDVAVMMVEAGASENVVNRVKDGAPAPTEKIVSDGLEAAKPFIDILCRAQEGLAQRVGNAAKEFPLFPPYTDEVYSAVERKVSKKLASLLTLKAKQERDDATNAYMEEIEAELLPKFEASYSSAAEASKEIRAAYNAVMKSIVRRMILTDHFRIDGRGVTDIRDLAVEVELIPRAHGSSLFERGETQILGVTTLDMLKMEQQIDSLAPGDAKRYMHHYNFPPYSTGETGRVGSPKRREIGHGALAERAVLPVIPSREEFPYSIRQVSEALGSNGSTSMGSVCASTLSLYNAGVPLKAPVAGIAMGLVSGEIDGKTEYVALTDILGAEDAFGDMDFKVAGTADFITALQLDTKLDGIPSKVLSDALEQARDARLTILNTMADVINGPDEMSKFAPRITTVKIPVAKIGELIGPKGKNINALTEETGANISIEDDGTVFISAADGASAEAAIEKINALANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVEKVDDVVKVGEKIQVEIADIDNRGKISLVPVAEED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BINL_STAAU
Sequence: MKIGYARVSTGLQNLNLQEDRLNAYGSEKIFSDHISGSKSKRPGLDKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSTSTGQLLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNQKDLNLLKTLYDNGTPIKTIAEQWQVSRTTIYRYLNKLEEKEDEKQGEVSN
What is the function of this protein?
Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.
What are the official names of this protein?
Transposon Tn552 resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: XGPT_IDILO
Sequence: MGWHSNREFFVSWEELHRATRELARRQLPAEQYKGIIAVSRGGLVPAAIVSRELNIRVVDCVAVSSYDHTEQRDDLQVMKDVTATEDGEGFLVVDDLVDTGNTMKFLRERLPKAKFVTVYAKPSGMEMVDDFVADLAQDTWIHFPWDMHLHYIEPLAGQES
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DSBB_PSYA2
Sequence: MLQLTTYRNLQVFLVIMTAIGMSFALFFLQRYMGFSPCPLCIFQRIGLMIMGGFALIAALFHPKSMVIRLLLWLGSLAGIGWAAIVAGRHVWLQHLPADQVPSCGPGLDYWLDTLPMQQVLKEVFAGSGECASIEWTFLGLSIPEQSLILFSILILTHLLILWRIVRPSTPKPLAR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WHIB2_BIFLO
Sequence: MWGVVDDSAEEPWHELWGLFRPDGDVSWQHKALCAQTDPEAFFPEKGGSTRDAKRVCAKCEVREQCLKWAIDHDERFGIWGGMSERERRRYKREHRERA
What is the function of this protein?
Acts as a transcriptional regulator.  Probably redox-responsive.  The apo- but not holo-form probably binds DNA (By similarity).
What are the official names of this protein?
Transcriptional regulator WhiB2.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADB_METJA
Sequence: MLKEILLGNAEKGIITQIYGPPGVGKTNICIINSINAVNSGKVIYIDTEGGLSIERIKQIASNNYKIVLENMIIYNAFDFYEQDKIIQKELPLITNNASLIVVDNITSLYRLELSDEANKNIMLNKMLGNQVKTLLKLAKTNNLAVIITNQVRETVNGFEASGGRLLEYWSKCIVRLEKLNGDRLAILEKHLHAGEERVKFRIVERGIEIID
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.