PharMolix/UniProtQA huggingface dataset:
Protein: RL3_METPP
Sequence: MTTANPGDRLGLLGRKVGMMRIFTDDGDAVPVTVLDVSNNRVTQVKTVETDGYSAIQVTFGARKASRVTKPEAGHLAKAGVEAGEILREFAVSAEVAAEYKPGGTLPVGLFAAGQKVDVQGTSIGKGFTGTIKRHNFGSQRASHGNSRSHNVPGSISMAQDPGRVFPGKKMSGHRGDVTKTTQNLDIVRVDEARQLLLVRGAVPGAKNGFVTVRPAVKVKAKKGAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: AT1A4_RAT
Sequence: MEPGKETAATSEQKPRPTLRASNTNRQPKVKRRKKDLEELKKEVVMDDHKLTLDELSAKYSVDLTKGLSVTDAQEILTLNGPNVLTPPPTTPEWIKFCKQLFGGFSLLLWTGSLLCFLAYGIHVSYYQENANKDNLYLGIVLSAVVIITGCFSYYQEAKSSKIMESFKTMVPQQALVIRDGEKMQINVRDVVLGDLVEVKGGDQVPADIRVIAAQGCKVDNSSLTGESEPQSRCPDCTHENPLETRNIIFFSTNCVEGTARGVVIATGDHTVMGRIASLTSGLTMGKTPIATEIEHFIHIITAVAVFLGVTFFFLSLILGYTWLDAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTVYEADTSEEQTTGKTFPKSSDTWFYLARIAGLCNRADFKPHQESLPITKRTTTGDASESALLKFIEQSYSPVSEMRQKNPKVAEIPFNSTNKYQMSIHLLEDNSEAHVLLMKGAPERILDFCSSFLLNGQEYPMDEEMKTDFQNAYIELGGLGERVLGFCFLNLPSNFSKGFQFNTEELNFPMENLCFAGLISMIDPPRTAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKSVGIISEANETAEDIAARLNISISQVSNKSIKAIVVHGSELKDMDSGQLDNILKSYKEIVFARTSPQQKLIIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIVLSIPLPLGTITILCIDLGTDMVPAISLAYETPESDIMKRLPRNPKTDNLVNDRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPLDLLGIRLYWDDTNLNDLEDTYGQQWTYEQRKVVEFTCQTAFFISIVIVQWADLIICKTRRNSLFKQGMKNKVLIFGLLEETILAACLSYIPGMDVALRMYPLKINWWFCALPYSVLIFIYDEVRKLIIRRRPGGWLEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.  Plays a role in sperm motility.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-4, Na(+)/K(+) ATPase alpha-4 subunit, Sodium pump subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALR_STRCO
Sequence: MTTRLADIAAQAGVSEATVSRVLNGKPGVAATTRQSVLAALDVLGYERPVRLRQRSEGLVGLITPELENPIFPALAQVIGQALTRQGYTPVLATQTPGGSTEDELTEMLVDRGVAGIIYVSGLHADTTADMQRYERLRAQGVPFVLVDGFSSQVQAPFISPDDRAAMSLAVTHLVSLGHTRIGLALGPKRFVPVQRKIEGFVRTVQDQLGLSAETVEKELVQHSLYTLEGGQAAASALIGRDCTAVVCASDMMALGAIRAARQLGLDVPKDVSVVGFDDSPLIAFTDPPLTTVRKPVPAMGQAAVRTLLEEIGGTPAPHSEFVFMPELVVRGSTASAPGERGRP
What is the function of this protein?
Transcriptional repressor of the maltosaccharide utilization operon malEFG.
What are the official names of this protein?
HTH-type transcriptional regulator MalR, Maltose operon transcriptional repressor.
Protein: SQD1_ARATH
Sequence: MAHLLSASCPSVISLSSSSSKNSVKPFVSGQTFFNAQLLSRSSLKGLLFQEKKPRKSCVFRATAVPITQQAPPETSTNNSSSKPKRVMVIGGDGYCGWATALHLSKKNYEVCIVDNLVRRLFDHQLGLESLTPIASIHDRISRWKALTGKSIELYVGDICDFEFLAESFKSFEPDSVVHFGEQRSAPYSMIDRSRAVYTQHNNVIGTLNVLFAIKEFGEECHLVKLGTMGEYGTPNIDIEEGYITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWGIRATDLNQGVVYGVKTDETEMHEELRNRLDYDAVFGTALNRFCVQAAVGHPLTVYGKGGQTRGYLDIRDTVQCVEIAIANPAKAGEFRVFNQFTEQFSVNELASLVTKAGSKLGLDVKKMTVPNPRVEAEEHYYNAKHTKLMELGLEPHYLSDSLLDSLLNFAVQFKDRVDTKQIMPSVSWKKIGVKTKSMTT
What is the function of this protein?
Involved in the biosynthesis of sulfolipids found in thylakoid membranes.  Converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose.
What are the official names of this protein?
UDP-sulfoquinovose synthase, chloroplastic, Sulfite:UDP-glucose sulfotransferase, Sulfolipid biosynthesis protein.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DJC11_HUMAN
Sequence: MATALSEEELDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQTRAIYDIYGKRGLEMEGWEVVERRRTPAEIREEFERLQREREERRLQQRTNPKGTISVGVDATDLFDRYDEEYEDVSGSSFPQIEINKMHISQSIEAPLTATDTAILSGSLSTQNGNGGGSINFALRRVTSAKGWGELEFGAGDLQGPLFGLKLFRNLTPRCFVTTNCALQFSSRGIRPGLTTVLARNLDKNTVGYLQWRWGIQSAMNTSIVRDTKTSHFTVALQLGIPHSFALISYQHKFQDDDQTRVKGSLKAGFFGTVVEYGAERKISRHSVLGAAVSVGVPQGVSLKVKLNRASQTYFFPIHLTDQLLPSAMFYATVGPLVVYFAMHRLIIKPYLRAQKEKELEKQRESAATDVLQKKQEAESAVRLMQESVRRIIEAEESRMGLIIVNAWYGKFVNDKSRKSEKVKVIDVTVPLQCLVKDSKLILTEASKAGLPGFYDPCVGEEKNLKVLYQFRGVLHQVMVLDSEALRIPKQSHRIDTDG
What is the function of this protein?
Required for mitochondrial inner membrane organization.  Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex.
What are the official names of this protein?
DnaJ homolog subfamily C member 11.
What is the protein family that this protein belongs to?
Belongs to the DNAJC11 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Isoforms show differential submitochondrial localization. A 57 kDa form (potentially isoform 3) shows either mitochondrial matrix or innermembrane (IM) localization, possibly anchored to the IM facing the matrix. A 35 kDa form behaved either as an inner membrane space (IMS) or an IM protein exposed to the IMS. SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion outer membrane; Peripheral membrane protein.
Protein: RS6_RHIEC
Sequence: MALYEHVFLARQDISAQQVDALVEQYKGVIEANGGKVGRIENWGLKSLTYRIKKNRKAHYALMDIDAPPAAIQEMERQMRISEDVLRYMTIAVEKHEEGPSAMLQKRDRDDRGPREGGDRGPRREFGDRPPRRDGDFQRGPRPDRAPREDRA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PSPB_RABIT
Sequence: MAKSHLPPWLLLLLLPTLCGPGTAVWATSPLACAQGPEFWCQSLEQALQCKALGHCLQEVWGHVGADDLCQECQDIVNILTKMTKEAIFQDTIRKFLEHECDVLPLKLLVPQCHHVLDVYFPLTITYFQSQINAKAICQHLGLCQPGSPEPPLDPLPDKLVLPTLLGALPAKPGPHTQDLSAQRFPIPLPLCWLCRTLLKRIQAMIPKGVLAMAVAQVCHVVPLVVGGICQCLAERYTVILLEVLLGHVLPQLVCGLVLRCSSVDSIGQVPPTLEALPGEWLPQDPECRLCMSVTTQARNISEQTRPQAVYHACLSSQLDKQECEQFVELHTPQLLSLLSRGWDARAICQALGACVATLSPLQCIQSPHF
What is the function of this protein?
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.  SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
What are the official names of this protein?
Pulmonary surfactant-associated protein B, SP-B, 6 kDa protein, Pulmonary surfactant-associated proteolipid SPL(Phe).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: NA116_ANTS7
Sequence: GVPCLCDSDGPSVRGNTLSGTLWLFGCPSGWHNCKAHGPTIGWCCKK
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction (By similarity).  Stimulates mammalian heart contraction (PubMed:14672713).
What are the official names of this protein?
Delta-actitoxin-Aspp1d, Delta-AITX-Aspp1d, Toxin Hk16a.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CEMA_CALFG
Sequence: MPKKKALTPFPYLASIVFLPWWISLSFTKSLEPWVTNWWNTGQSKTFLNDIQEKNVLERFIELEQLFLLDEMIKEYPETQIQKFHIGIHKETLQLVKMHNEDHIHIVLHFSTNIICFAILSGYYFLGNEELVILNSWVQEFLYNLSDTIKAFSILLVTDLCIGFHSPRGWELMIGSVYKDFGFAHNDQIISGLVSTFPVILDTILKYWIFHYLNRVSPSLVVIYHSMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: TCPZ_CHICK
Sequence: MAVKALNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLQEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIVAEGFEIAKEKALEVLEQVKVTKEMDRETLIDVAKTSLRTKVHTELADILTEAVVDSVLAVRKPGEPIDLHMVEIMEMKHKSETDTTLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVSAGFFYKSAEEREKLVKAERKFIEDRVSKIIDLKRRVCGDSDKGFIVINQKGIDPFSLDALAKEGIVALRRAKRRNMERLTLACGGTAMNSVEDLTPDCLGHAGLVYEYTLGEEKYTFIEKCDNPRSVTLLIRGPNKHTLTQIKDAVRDGLRAVKNAIEDGCVIPGAGALEVAVANALVKHKPNVKGRAQLGVQAFADALLIIPKVLAQNSGYDPQETLVKVQAEHAESGQLTGVDLNTGEPMVAAAAGIWDNYNVKKQLLHSCTVIASNILLVDEIMRAGMSSLKG
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit zeta, TCP-1-zeta, CCT-zeta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_BRUO2
Sequence: MKPKIFIDGEHGTTGLQIRTRLAERDDLEVISIPEAERRNKDLRADYLRAADIAILCLPDDASKEAVSLLEGHNSTRIIDTSTAHRVHPDWAYGFAELAKGQRERIAEARLVANPGCYPTGAIALVRPLCDAGLLPADYPVSVNAVSGYTGGGKQLIAQMEDRNHPDYLAANNFLYGLPLKHKHVPELQLHGRLDRRPIFSPSVGRFPQGMIVQVPLFLSELEGSPSLAKVHAVLTEHYAGQDIVEVVPLEESAKLPRVDAEELAGKDGMKLFVFGTEDHGQVNLVALLDNLGKGASGAAVQNMNLMLGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4757_BACMK
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYDYMDENPMF
What are the official names of this protein?
UPF0349 protein BcerKBAB4_4757.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: RL31B_MICLC
Sequence: MKSEIHPDYHYVIFNDLASGEKILTRTTANSDKTAEWTDGNTYPVIDVEISAASHPFYTGKQRIMDTAGRVERFNARFKGFGGKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PSRP_VIBC1
Sequence: MQINSQSRDVFYVSDGTAITCETLGHVVLGQFSLIPNEKTFPFVESEDKVADVIKEIEISYQRDGVKPLVFFSIVVPEIREMLLKAPAHGYDVLESIVQKVQDDIQMEPQPKMQRSRSVSKDSDTYFDRIAAIEYTLAHDDGITLKGLDEANIILLGVSRSGKTPTSLYMAMQFGLRVVNYPFIAEDVKMMRLLPEFEIHRHKLFGLTINPERLNEIRENRLSGSEYASTEQCKLELDTVEALFRREAIPYINTSSLSVEEITTRILERAGMKRRLFG
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: CTU1_HUMAN
Sequence: MPAPPCASCHAARAALRRPLSGQALCGACFCAAFEAEVLHTVLAGRLLPPGAVVAVGASGGKDSTVLAHVLRALAPRLGISLQLVAVDEGIGGYRDAALAAVRRQAARWELPLTVVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARRVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGGLGSPGEGGALPRCRPLQFASQKEVVLYAHFRRLDYFSEECVYAPEAFRGHARDLLKRLEAARPSAVLDLVHSAERLALAPAARPPRPGACSRCGALASRALCQACALLDGLNRGRPRLAIGKGRRGLDEEATPGTPGDPARPPASKAVPTF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_LEPBJ
Sequence: MQESGLKPILWTNKELILLDQRVLPGTTSYLKAKTLEDCIFAIREMVVRGAPAIAITGAFGIALYLNGLSSQPTFSQLKTKLDELLESRPTAVNLRLVIEEFFSRFPEADYSSANLEKMQKSAEEFALFMLEEDLENNLTLSKNALSLFPKSPSSLNIITHCNTGALATAGHGTALGVIRSLRDAGHSLTVFADETRPYLQGARLTAWELKEEGIPSYLITDNMAGWVMSSRKIHAVIVGADRIASNGDTANKIGTYPLAIIAKHHGVPFYVAATSKSMDFRIPDGSHIPIEMRKENEVTSFGFLKDATGKPLLNEGVLAPNGIKALNPSFDVTPASLISGIITERGIISPVTEENLRKTFS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: TM230_CHICK
Sequence: MMPSRTNLSAGIPSSKVKYSKLASTDDGYIDLQFKKSPPKIPYKAIALAVVLFMIGTFLIIIGALLLAGYISKGGTDRAIPVLIIGILVFLPGFYHLRIAYYASKGYRGYSYDDIPDFDD
What is the function of this protein?
Involved in trafficking and recycling of synaptic vesicles.
What are the official names of this protein?
Transmembrane protein 230.
What is the protein family that this protein belongs to?
Belongs to the TMEM134/TMEM230 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Early endosome. Recycling endosome. Late endosome. Cytoplasmic vesicle, autophagosome.
Protein: MASZ_PSEA7
Sequence: MTERVQVGGLQVAKVLFDFVNNEAIPGTGVSADSFWTGAEAVINDLAPKNKALLAKRDDLQAKINGWHQARAGQAHDAAAYKAFLEEIGYLLPEAEDFQAGTQNVDDEIARMAGPQLVVPVMNARFALNASNARWGSLYDALYGTDVISEEGGAEKGKGYNKVRGDKVIAFARAFLDEAAPLESGSHVDATSYSVKNGALVVALKNGSETGLKNAGQFLAFQGDAAKPQAVLLKHNGLHFEIQIDPSSPIGQTDAAGVKDVLMEAALTTIMDCEDSVAAVDADDKVVIYRNWLGLMKGNLAEEVSKGGTTFTRTMNPDRVYTGADGSELTLHGRSLLFVRNVGHLMTNDAILDKHGNEVPEGIQDGLFTSLIAIHNLNGNTSRKNSRTGSVYIVKPKMHGPEEAAFTNELFGRVEDVLGLPRNTLKVGIMDEERRTTVNLKACIKAAKDRVVFINTGFLDRTGDEIHTSMEAGAVVRKGAMKSEKWIGAYENNNVDVGLATGLQGKAQIGKGMWAMPDLMAAMLEQKIGHPLAGANTAWVPSPTAATLHALHYHKVDVFARQAELAKRTPASVDDILTIPLAPNTNWTAEEIKNEVDNNAQGILGYVVRWIDQGVGCSKVPDINDVGLMEDRATLRISSQLLANWLRHGVISQEQVVESLKRMAVVVDRQNASDPSYRPMAPDFDDNVAFQAALELVVEGTKQPNGYTEPVLHRRRREFKAKNGL
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS29_PANTR
Sequence: MTSGEVKTSLKNAYSSAKRLSLKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALRDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRQAQRQDGEEEDGREL
What is the function of this protein?
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity).  Involved in the modulation of intracellular signaling cascades.  In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase.  Affects MAP kinase signaling though modulation of the ERK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity).
What are the official names of this protein?
Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CATA_EMENI
Sequence: MATSITAGLQKAQQAVQDTATKNKKIVDISHDTVNVHTDQEQRTDFGVAITDPDHWLRVTNETHSGPSLLEDHIARERIHRFDHERIPERVVHARGTGAYGNFTLKESIEDLTYAGVLTDTSRNTPVFVRFSTVQGSRGSADTVRDVRGFAVKFYTDEGNWDIVGNNIPVFFIQDAIKFPDFVHAVKPEPHNEVPQAQTAHNNFWDFVYLHPEATHMFMWAMSDRAIPRSYRMMQGFGVNTFSLVNKEGKRHFVKFHWIPHLGVHSLVWDEALKLAGQDPDFHRKDLMEAIDNKAYPKWDFAIQAIPEEDQDKFEFDIFDATKVWPEEQVPLRVVGELELNRNIDEFFPETEQVAFCTSHIVPGIDFSDDPLLQGRNFSYQDTQISRLGVNWEEIPINRPVCPFLNHNRDGAKRHRITKGTVNYWPNRFEANPPASDKGFKSHPAPITGRKRRDLTPKFKEYHNQAQLFYNSLSEVEKVHVKKAFSFELDHCDDPIVYERLAGQRLAEIDLPLAQAVAEMVGAPIPTKALRDNHGKTSVRLSQFDFTPKAPGIISRRIAIIIGDGYDKIAFNGMKAAILAAQALPFVIGTKRSAIYAQGEDKNSSKGVIPDHMYDGMRSTMFDATFIPGGSHIETLQKNGQIRYWIAETFGHLKALGAMGEAAQLVKEVLGNVMGVQIAGADSAEPVEWYGVVTARGPESAESLSEGFKVLKDAGDFTSKFFYQISQHRNWQRELDGLASTVAF
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase A, Spore-specific catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: HIS7_POLNS
Sequence: MRQADVTRNTSETKIQISINLDGTGKAELASGVPFLDHMLDQIARHGMIDLKVVANGDAHIDDHHTVEDVGITLGQAFAKAVGDKVGITRYGHSYVPLDETLSRIVIDFSGRPGLEFNVPFTRARVGDFDVDLSIEFFRGFVNHAGVTLHIDNLRGINAHHQIETVFKAFGRALRMALAVDPRASGSIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_PSEU2
Sequence: MSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALSKPELLEGGAELKIRVSFDKDAKTVTLEDNGIGMSREDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADQVEVFSRRAGTPASEGVHWSSKGEGEFEVATVDKADRGTRIVLHLKNGEEEFADGYRLRNIIKKYSDHIALPIELPKEQAPAAEGEEPAALEWETVNRASALWTRPRTEVKDEEYQEFYKHVAHDYENPLSWSHNKVEGKLEYTSLLYVPARAPFDLYQREAPRGLKLYVQRVFVMDQAESFLPLYMRFVKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEKYKGFWKNFGQVLKEGPAEDFANKEKIAGLLRFASTSDDSGEQSVSLAEYLARAKEGQDKIYYLTGESYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSDFDGKGFVDVARGDLDLGNLDSEEDKKAQEEIAKDKEGLIERLKAALGESVSEVRVSHRLTDSPAILAIGEQDMGLQMRQILEASGQKVPDSKPIFEFNPAHPLIGKLDAEQSEDRFGDLSHILFDQAALAAGDSLKDPAAYVRRLNKLLVELSV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPPE_GLOHA
Sequence: VIGGDECNINEHRFLVALYTSRTLFCGGTLINQEWVLTAAHCNMEDIQIKLGMHSKKVPNEDEQKRVPKEKFFCLSSKKLYLWDKDIMLIRLDSPVKNSAHIAPLSLPSSPPSVGSVCRTMGWGRISSTKETYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTCVGDSGGPLICNGQFQGIASWGDHPCAQPHKPAAYTKVFDHLDWIENIIAGNTDASCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease pallase, SVSP pallase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS2_BRUSU
Sequence: MSQFTLADLERIVAERASVTDGTSYTASLVAKGQPKAAQKLGEEAVETVIAAVSGDRAGVVSESADLLYHLAVVWNIAGVALEDVLQELQRRTAQTGLAEKASRPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIN7C_MOUSE
Sequence: MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (PubMed:10846156).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
What are the official names of this protein?
Protein lin-7 homolog C, Lin-7C, mLin7C, Mammalian lin-seven protein 3, MALS-3, Vertebrate lin-7 homolog 3, Veli-3.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: PCKA_MARMM
Sequence: MSKSERLDGGLEALGIQAGTVNLNWNEPRLYQEAVQRGEAEVAEGGALVVKTGAHTGRSAKDKFTVRDSETEDQVWWDNNAAISPEHFDALWTDFQAHMAGKELFVQQLFGGADLDHRLPVRVVNELAWHSLFIRHLLRVPAAEEYAGFAAEFTIINLPSFKADPARHGCRSETVIGVDFARRIVLIGGTSYAGETKKSVFTILNYLLPAKGVMPMHCSVNSNPNGEDATIFFGLSGTGKTTLSADASRTLVGDDEHGWSPNGLFNFEGGCYAKMIRLSAEAEPEIHATTKMWGTVLENVVMDPQTRVLDLDDDSLAENSRGAYPLSAIPNASETGRCGHPKNVIMLTCDAFGIMPPIAKLTPAQAMYHFLSGYTAKVAGTEKGVTEPSATFSTCFGAPFMPRHPAEYGALLRELIAEHQVDCWLVNTGWTGGAYGTGNRMPIKATRALLNAAMDGSLNSAAFREDPNFGFMVPIAVDGVDASILDPRSTWSDKAAYDDRAAKLATMFIENFKTFEAHVAPYVRAAAPKVRELTAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_BACHK
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMEGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.