PharMolix/UniProtQA huggingface dataset:
Protein: OTNK_BRUME
Sequence: MPASNFPTGVHDMRLGVIADDFTGATDIAGFLVGNGLRTIQLNGVPADDLAVDADAVVISLKARSCPTGQAIAESLAALKWLQKNNCQQFFFKYCSTFDSTPKGNIGPVTDALLEALGEEFTVICPALPVNGRTIYNGYLFVNGVLLSETGMRNHPVTPMTDSNIMRVMESQSRGRAGNISSTIVDQGSDAVRDALRKLQSEGIRYAVLDALNDQHIETLGRAVSQMKLVTGGSGLADGMARAWTQLRGKNVAAAEAAGAPVKGRTVILSGSCSQMTNAQVAAYKAKAPALAMDVEKAINDAAYIDVLAEWVLAQSGDALPPLVYATMPPEALKAVQERFGGERASAAIEDLFGQLAKRLEAEGFTRFIVAGGETSGAVTQALAIDGFTIGPQIAPGVPWVRGIGKPLSLALKSGNFGTEAFFFEAQKIANQEGDK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.
What are the official names of this protein?
3-oxo-tetronate kinase, 3-dehydrotetronate 4-kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: LCL3_PICST
Sequence: MAPIPQNSSTEVSLLHPKVLLLSAGITTTAFLSYKFHQRYVTRLRTYLDITPKILDNQQKLYGYVTRVGDGDNFRFFHTPGGVFMGWGWLRKIPTNRNQLKDETLMIRLCGVDAPERSHWGKPAQPFSEEALIWLSSYVGKRYVTVTPFSIDQYKRLVARAQVWKWTGKKDVSAEMIRQGLGIVYEGKSGAEFGDNEALYRNLEAKAKRQKKGVWSLGKKMTTPGEFKREHYRGD
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: PG030_VAR67
Sequence: MDTYMNRLDLDKLKHENIFSGNIIEDAKEFVFGSRKIYTDSVNDLIELYNLAKYLNNEKLKDVVIERMDYVCKYIIGKDNWYTIYSFYKENGLRNSFLRQYINNNIEEIRNTDQFLKFDVDSVCDILNNDETIV
What are the official names of this protein?
Protein OPG030.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG030 family.
Protein: RSMA_TREPA
Sequence: MCCPNYNSARALAQFLTERGLRMHKKWGQNFLLDPVLRTQLVKILAPERGERVWEIGAGIGAMTALLVQNSDFLTVFEIDRGFVQTLRKLFDAHVRVIEGDVLQQWHAAAAQEQPACVLGNLPYNIAARFIGNTIESGYIFKRMVVTVQKEIGLRMTALPAQKWYSYFSVLCQWQYEVRVIRNVAPVCFWPRPHVVSQALVLTKRNAVPSCVDPALFLHVTKTLFSARRKTVRNNLLTWQKRMPGGAAVCVEELCARAGIDARARAEQLSIYDFITLSDTLRALL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_BACP2
Sequence: MRLVVQRVTSASVKVEEEITGAINEGYMVLVGVTHEDTEEDVHYLADKLAHLRIFEDENGKMNHSLLDVKGSVLSVSQFTLYGDTRKGRRPNFMKAAKPDAANALYECFNKALREKGIHVETGRFGAMMDVSLTNSGPVTIWMDSKE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F172A_DANRE
Sequence: MFFRASFFLFGLVWITMAQLLAQDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPETLDGFEYAFNEQGQLRHTKTGEPFVFNYKEDLHRWNQKRYEALGEIITKYVYERLEKDCNLKKEILPVDATEDEPKSFIYVSEDALSNPDKIMVLIQGSGVVRAGQWARRLIINEDLNSGTQIPFINRAKEEGYGVIVLNPNENSLEVEKVSDPAKKASPDASDEPAEKRERKEERENKKKKDFYEKYRNPQKEREMEHIPIRENGSPEEHTLYAWDYFISKSLAKNIFIVAHSYGGLSFVNLMINREAEVKSRVRAVAMTDSVHNVWHQEASKSIQDWLREHCCNWVSSPEPLDTLVDPMLNDCPRVSAGTEKHELTSWKSFQSIFKFFSNALKDHEDDSSSSPVTTRSSHRIKHEDF
What is the function of this protein?
May play role in the regulation of alternative splicing.  May have hydrolase activity.
What are the official names of this protein?
Cotranscriptional regulator FAM172A homolog, Protein FAM172A.
What is the protein family that this protein belongs to?
Belongs to the FAM172 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FIM1C_ECOL6
Sequence: MKLKFISMAVFSALTLGVATNASAVTTVNGGTVHFKGEVVNAACAVNTNSFDQTVNLGQVRSERLKVDGAKSNPVGFTIELNDCDSQVSAGAGIVFSGPAVTGKTDVLALQSSAAGSATNVGVQITDHTGKVVPLDGTASSTFTLTDGTNKIPFQAVYYATGQATAGIANADATFKVQYQ
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein, C chain, Type-1C pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: RS2_SYNSC
Sequence: MAVVTLAEMMEAGAHFGHQTRRWNPKMSRYIYCARNGVHIIDLVQTAVCMNNAYKWTRSAARSGKRFLFVGTKKQASEVVALEAARCGASYVNQRWLGGMLTNWTTMKARIDRLKDLERMESSGAIAMRPKKEGAVLRRELERLQKYLGGLKNMRRLPDVVVLVDQRRESNAVLEARKLDIPLVSMLDTNCDPDLCEVPIPCNDDAVRSVQLILGRLADAINEGRHGSNDQRGGDSEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: XERC_ECOK1
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIIHFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPO_TAKRU
Sequence: MLQKTGRGLLAFLLIVLEWTQPSLPSPLRPICDLRVLNHFIKEAQDAEAAMKLCSEGCTLSDSVIVPQTTVEFDVWEKKSALAKAQEVQSGLWLLQEAFNFLRTSVTNTALHSHIDNSVRNLLSVNAVLRSLNIQEFTPPASAAEIEGTWRVSTATELLQVHINFLRGKVRLILLDAQACQQDVS
What is the function of this protein?
Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_SHIFL
Sequence: MKSYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: DCE1_ARATH
Sequence: MVLSHAVSESDVSVHSTFASRYVRTSLPRFKMPENSIPKEAAYQIINDELMLDGNPRLNLASFVTTWMEPECDKLIMSSINKNYVDMDEYPVTTELQNRCVNMIAHLFNAPLEEAETAVGVGTVGSSEAIMLAGLAFKRKWQNKRKAEGKPVDKPNIVTGANVQVCWEKFARYFEVELKEVKLSEGYYVMDPQQAVDMVDENTICVAAILGSTLNGEFEDVKLLNDLLVEKNKETGWDTPIHVDAASGGFIAPFLYPELEWDFRLPLVKSINVSGHKYGLVYAGIGWVIWRNKEDLPEELIFHINYLGADQPTFTLNFSKGSSQVIAQYYQLIRLGHEGYRNVMENCRENMIVLREGLEKTERFNIVSKDEGVPLVAFSLKDSSCHTEFEISDMLRRYGWIVPAYTMPPNAQHITVLRVVIREDFSRTLAERLVIDIEKVMRELDELPSRVIHKISLGQEKSESNSDNLMVTVKKSDIDKQRDIITGWKKFVADRKKTSGIC
What is the function of this protein?
Catalyzes the conversion of glutamate to 4-aminobutanoate (GABA).  The calmodulin-binding is calcium-dependent and it is proposed to directly or indirectly form a calcium regulated control of GABA biosynthesis.
What are the official names of this protein?
Glutamate decarboxylase 1, GAD 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RL4_CORA7
Sequence: MSNLKLDVQTADGKTNGTVELPAELFDTEASIALMHQVVNAQLAAARQGTHKTKTRGEVRGGGRKPFRQKGTGRARQGSIRAPHYTGGGTVHGPVPRDYSQRTPKRMIKAALYGALSDRARNERIHVIEELVPGQTPSTKQAKAFIERLTDRKNVLLVIGREDINARRSANNLPNVQILDAGQLNTYDVLYSDDVVFSVEALHTFVERATGAAEEAKEEK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TRPA_ECOLI
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CAL_ARATH
Sequence: MGRGRVELKRIENKINRQVTFSKRRTGLLKKAQEISVLCDAEVSLIVFSHKGKLFEYSSESCMEKVLERYERYSYAERQLIAPDSHVNAQTNWSMEYSRLKAKIELLERNQRHYLGEELEPMSLKDLQNLEQQLETALKHIRSRKNQLMNESLNHLQRKEKEIQEENSMLTKQIKERENILRTKQTQCEQLNRSVDDVPQPQPFQHPHLYMIAHQTSPFLNMGGLYQEEDQTAMRRNNLDLTLEPIYNYLGCYAA
What is the function of this protein?
Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1, FRUITFULL and LEAFY.  Is required subsequently for the transition of an inflorescence meristem into a floral meristem.  Seems to be partially redundant to the function of APETALA1.  Positively regulates the APETALA1 and LEAFY expression.
What are the official names of this protein?
Transcription factor CAULIFLOWER, AtCAL, Agamous-like MADS-box protein AGL10.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHRD1_PONAB
Sequence: MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKPPESVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLKLSSGNEENKKEEDNDEIKIGTSCKNGGCSKTYRGLESLEEVCVYHSGVPISHEGMKYWSCCRRKTSDFNTFLAQEGCTKGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLLNVHIVFEGEKEFEQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASLELPAAKKQEKQKDDTTD
What is the function of this protein?
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2.  Proposed to act as co-chaperone for HSP90.  May play a role in the regulation of NOD1 via a HSP90 chaperone complex.  In vitro, has intrinsic chaperone activity.  This function may be achieved by inhibiting association of ROCK2 with NPM1.  Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling (By similarity).  Involved in stress response.  Prevents tumorigenesis (By similarity).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, CHP-1, Protein morgana.
Protein: MNME_TRIV2
Sequence: MTQLLAITGTIAAIATAIVPQQGSVGIVRVSGSQAIAIAQTLFHAPGKQVWESHRILYGYIRHPQTRQIVDEALLLLMKAPRSYTREDVVEFHCHGGIMAVQQVLQLCLEGGARLAQPGEFTLRAFLNGRLDLTQAESIADLVGARSPQAAQTALAGLQGKLAHPIRQLRANCLDILAEIEARIDFEEDLPPLDDEKIISDIENIAAEISQLLATKDKGELLRTGLKVAIVGRPNVGKSSLLNAWSQSDRAIVTDLPGTTRDVVESQLVVGGIPVQVLDTAGIRETSDQVEKIGVERSRQAANTADLVLLTIDAATGWTTGDQEIYEQVKHRPLILVMNKIDLVDKKLITSLEYPKNITQIVHTAAAQKQGIDALETAILEIVQTGKVKAADMDLAINQRQAAALTQAKISLEQVQATITQQLPLDFWTIDLRGAIQALGEITGEEVTESVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRL1_MOUSE
Sequence: MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
What is the function of this protein?
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.  Involved in formation of autophagosomal vacuoles.  While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.  Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein-like 1, GABA(A) receptor-associated protein-like 1, Glandular epithelial cell protein 1, GEC-1.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Endoplasmic reticulum. Golgi apparatus.
Protein: PSBC_LACSA
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAAISVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SERC_ECO27
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGFRAVKPMSEWQLSDNAAYMHYCPNETIDGIAIDETPNFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVVAMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMB_RALP1
Sequence: MIHALEQGGVARGIAQAARVAVLALAATAVLGGCSLFSSKNKHEPAKLMEVQQVLAVRQVWSVSVGKSGRYVMQPAVAGNNVYVSAAGGTVTALDGATGRTVWQGKADVDLTTGPGSDGTLTAVAGEKGAVIAFDEKGAQKWKVAVNGEVLTAPLVGQGLVIVRTTDGRVLGLDPSNGERKWIYQRSPSALNLRSSLPMIFAGDNIILGFAGGKLGALSASNGALRWEAAVSYPRGVSEIERLNDVTGAPSVNGSQVCAASFQGRVACFDMSTGAPRWGRDFSSPTGVTQDDGGLFAADEKSVVYGFNAQNGADLWKNDALLWRDLGTPLAFGRAVIVGDSEGWLHFLSRDDGKFVARVKTDGSAIGAAPVVVGQTLVVQTRGGGVYGYLPK
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamB.
What is the protein family that this protein belongs to?
Belongs to the BamB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CRBN_DROPS
Sequence: MDEEETAEINAQEQEVAGSAGEAAAGPSGAEVQPNDDSVAVERVIDVFEETAEMEAAMIERFFGPSGEVAEEGTLPVPGPSADGEGSANAGGERPSEEDIVLDDGTESDGSYNRPGSDMSLDSPNSEDDSDVEAMPRWMIPQNRLRFAVDMMVSQARNQDGGIAALLNRDNFLQRVRSMVFSQERRRSRNSDEVSPEAEDDELPEHPPPPPPRPPIDIDMEEGVHFDTNLPAEHSYFGPNLNRVPGVNYQEVGSTHHMLIFLHQYILFPGEVLPFMIDGSLFDDDMSGLDGLIFAVAFPLMKPPEDSKKLYGVTCQIYEKGDNGRHLTFYKSRALQRIVINCSDIKGLPQYIARNPTNKCHSKVKILPEYFLPEPLKCIDMGSMSRFRDIPSMRDKYLRYQISSTPWPVEVCQEYAYEDIVERARKKLEVHKIDTMPKCPIQMSFWLVRNLHLTEKMMSQMFLTDSVNLRLQLIGGILKEETLFYCRYCNSSLAYCSDLFAMSKHGVQTQYCNPGGYIHETNTVYRVISHAIGYSGEPSTRFSWFPGYQWHIILCKFCAQHVGWEFKAVEPNLAPKMFYGLAGSSVRIGKAGDSATVNGNNFVVRNMLRVISEGME
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Has an essential role in mediating growth by negatively regulating insulin signaling.  It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
What are the official names of this protein?
Protein cereblon, Protein ohgata.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_CLOD6
Sequence: MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGADELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSINSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVKGVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKSNVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAD3_CAEEL
Sequence: MSLSLHLSGWPENSESRQRMLESSSSTNFVQHFVSREISNKERLLSLFRRLRNGLVLVLTPLFFGQMLNWEGPEWKCAYCVCIIAVYWMSEVMPLAVTAMLPVVLFPLVGVLDANTTAKEYMNDTNFLFIGGLIMAAAVEKCDLHERVALSVLRCVGSEPKWIMLGFMTVTALLSSFISNTATTAMMVPIGQSVVQQLISSFQHHPTNGERGRLGCKKMATGLVLSICFAANIGGTGTATGTPSNLVMLGQLSALFPKVDGSLNYVTWIFFAYPLMLLCLFVAWMTLVSFFLRDAPEKDEAVTEMLKTRYNELPRMTYAEKSVFVCFCILLSLWVFRNPGVVPGFGVFFKKGAYTDATSAMIVAFLLFVLPSERPDLATYIKKEDLKKRGCLMDWKTMQETFPWSVVLLLGGGFALAAGVKESGLSLLIGNSLSSIEHLPLWILQLLTMLIAMVITNICSNTVTASIFVPIVATLAQRAGHHPFTLMLPTTLASSFAFIFPVGTPPNAIVFGSGMVKVSDMAFVGGIISLELLVLTVLYMNSIAYLTLPLLEFPTWAIIANSTMQQ
What is the function of this protein?
High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms.  There is no interaction with monocarboxylates.  Plays a role in the regulation of life span.
What are the official names of this protein?
Sodium-dependent high-affinity dicarboxylate transporter 3, Na(+)/dicarboxylate cotransporter 3, NaDC-3, ceNaDC3.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATL22_ARATH
Sequence: MTSKLLPLLLNLIFLFFFPLLNASEQKPCYSFSCSQESVVARFPFSLFSYQPESCGYSGFNLICKDDANTTLKLPKSEPFLVKEIDYETQRIRLNDPENCLARRLLNFDPSGSPFSFLRSRNYTFLICPKEANITASFRAIDCLGNTTSSFFVVQFENLGSMPSSCHIFKILPLPFSWFVAYTTYPDGQNSRDMWLKWDSPDCRDCERRTNSRCGFKNNTSHQVECFSSVNPGLHNTGLQVLKIMCLSLVGPLTALTFCVGLVMCSSERVSSQIQQAVVARLSGSVTSQPSNEVARIGLDESTIESYKKVELGESRRLPTGSNDVVCPICLSEYATKETVRCLPECEHCFHTECIDAWLKLHSSCPVCRSNPSPLRD
What are the official names of this protein?
RING-H2 finger protein ATL22, RING-type E3 ubiquitin transferase ATL22.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTAP_THEVB
Sequence: MTAKIGIIGGSGLYKMEALTDVEEVRLTTPFGDPSDAFICGKIGGVPVVFLARHGRHHHLLPTEIPFRANIYGFKSLGVEYLLSASAVGSLQEAVKPLDIVVPDQFIDRTRNRISTFFGDGIVAHIGFADPVCPALAGVLADAIADLNLPDVTLHRQGTYVCMEGPAFSTLAESNLYRSWGGTVIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPEHDSVTVEMIMGNLQRNVKNAQAIICETVKRVHAHPPVSKAHRALKNAILTPLDQVPAATKEKLHLLLAKYL
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: HEM3_DESHD
Sequence: MGSVKIGTRDSQLALWQAEWVKRKLEEYYPEREFVLVPMKTKGDKILDVPLAKIGDKGLFTKELEVGLLNGEIDCAVHSLKDLPTVLPPGLEIAAFCEREEPRDVFLSKDGTPLGSLPAGSIIGTSSLRRKAQLQNYRSDLSFADLRGNLQTRWRKLQESDMAGIVLAAAGVKRLGWEDRITEYISEEIMLSAVGQGAIAVEIAAQRADVREMLDLLNHGDTERAVKAERALLYRLEGGCQIPIGAWAVTEQQQIVLKGMVASLDGQRILKVTLSGEHPEELGRQAADLLIAQGALEILQEIRTPLEK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.