PharMolix/UniProtQA huggingface dataset:
Protein: LSRF_ECOSM
Sequence: MADLDDIKDGKDFRTDQPQQNIPFTLKGCGALDWGMQSRLSRIFNSKTGKTVMLAFDHGYFQGPTTGLERIDISIAPLFEHADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLVDAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIVAGCPVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1098_HAEIN
Sequence: MPVYSITDKDLSKRIQLKENKTLKEKTANYVSEGRAVLTDVICK
What are the official names of this protein?
Uncharacterized protein HI_1098.
Protein: BECN1_RAT
Sequence: MEGSKASSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGESQEEEANSGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEMLEQMNEGDSEQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQMQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSAPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
What is the function of this protein?
Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
What are the official names of this protein?
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells. SUBCELLULAR LOCATION: [Beclin-1-C 35 kDa]: Mitochondrion. Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Beclin-1-C 37 kDa]: Mitochondrion.
Protein: RECA_STRCT
Sequence: SSGKTTLTLHAVANAPRLGGSVAFIDAEHALDPEYAKKLGVDIDSLILSQPDNGEQALEIVDMLVRSGALDLIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITSALNQSKTTAIFINQLREKIGVMFGSPETTT
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_XYLFT
Sequence: MNNKHPKNKAKSTTTPKTIALNKRARHEYHLIERHEAGLELQGWEVKAIRAGRANLGDGYAYVRDGEIFLIGAQITPLIQASTHVVANDRRTRKLLLHRHQIDTLIGRVQREGFTLVPTAMYWSKNRVKMEIALAKGKQAHDKRHAEKEREWQRDKQRIMRAHNRNA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ERPA_ECO24
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: HEM3_CHLPN
Sequence: MLSVCYSDPCLSDFCQGKRPLRIASRNSNLAKAQVHECISLLRSWYPKLWFQLSTTETTGDREKKIPLHLVENSYFFTDGVDALVHKGVCDLAIHSAKDLPETPSLPVVAITRCLHPADLLVYADHYVHEPLPLSPRLGSSSLRRSAVLKQLFPQGQILDIRGTIEERLDQLHRGHYDAIVLAKAASLRLHLHHAYSIELPPPYHALQGSLAITAKDHAGKWKQLFTPIHCHSS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RL4_VIBC1
Sequence: MELMVKGADALTVSETTFGREFNEALVHQVVVAFAAGARQGTRAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIWRTGGVTFAAKSQDHSQKVNKKMYRGAMKSILSELVRQERLIVVDNFSVEAPKTKELVAKLKELELTDALIVTSEVDENLFLAARNLYKVDARDVAGIDPVSLIAFDKVVMTAEAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RND1_MOUSE
Sequence: MKERRAPQPVVVRCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETMDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSETSIHSIFRTASMVCLNKSSPVPPKSPVRSLSKRLLHLPSRSELISTTFKKEKAKSCSIM
What is the function of this protein?
Lacks intrinsic GTPase activity.  Has a low affinity for GDP, and constitutively binds GTP.  Controls rearrangements of the actin cytoskeleton.  Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments.  Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments (By similarity).
What are the official names of this protein?
Rho-related GTP-binding protein Rho6, Rho family GTPase 1, Rnd1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: MYSP_BLOTA
Sequence: MAARSAKYMYQSSRAGHGGDISIEYGTDLGALTRLEDKIRLLSEDLESERELRQRVEREKSDITVQLMNLTERLEETEGSSESVTEMNKKRDSELAKLRKLLEDVHMESEETAHHLRQKHQAAIQEMQDQLDQVQKAKNKSDKEKQKFQAEVFELLAQVETANKDKLVAQKTVEKLEYTVHELNIKIEEINRTVVEVTAHRQRLSQENSELIKEVHEYKISLDNANHLKGQIAQQLEDTRHRLEDEERKRSSLENHAHTLEVELESLKVQLEEESEARLELERQLTKANGDAASWKSKYEAELQAHVDEVEELRRKMAQKISEYGEQLEALLNKCSALEKQKARLQSEVEVLIMDLEKATAHAQALEKRVSQLEKINLDLKSKLEEVSMLLEQTQKDLRVKIADLQKLQHEYEKLRDQKEALARENKKLADDLAEAKSQLNDAHRRIHEQEIEIKRLENEREELAAAYKEAETLRKQEEAKNQRLTAELAQTRHDYEKRLAQKEEEIEALRKQYQIEIEQLNMRLAEAEAKLKTEVARLKKKYQAQITELELSLDAANKANIDLQKTIKKQALQITGLQAHYDEVHRQLQQAVDQLGVTQRRCQALTAELEEMRVNLEQALRAKRAAEQMHEEAVVRVNELTTINVNLASAKSKLETEFSALQNDYDEVHKELRISDERVQKLTIEVKSTKDLLESETERVTKLETIKKSLETEVRNLQIRIEEVEANALAGGKRVIAKLESRIRDVEIEVEEERRRHAETEKMLRKKDHRVKELLLQNEEDHKQIQLLQEMSDKLNEKVKVYKRQMQEQEGMSQQNLTRVRRFQRELEAAEDRADQAESNLSFIRAKHRSWVTTSQVPGGTRQVFVTEQESSNF
What is the function of this protein?
Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.
What are the official names of this protein?
Paramyosin.
What is the protein family that this protein belongs to?
Belongs to the paramyosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: JANA_DROOR
Sequence: MNRLQLLSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVMINVIDGGDASKAVIRGFADCTWHADIFDREEEVFKKLGLRAECPGGGRIEHNPDKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIETSDEGY
What is the function of this protein?
JanA and janB regulate somatic sex differentiation.
What are the official names of this protein?
Sex-regulated protein janus-A.
What is the protein family that this protein belongs to?
Belongs to the janus family.
Protein: ACKA_CLOBJ
Sequence: MKILVVNCGSSSLKYQLIDMTSEEALAKGLVERIGIEGSILTQKVNGEKYIIEEPMKDHKKAIELVLKALVDKEHGVISDMSEIAAVGHRVVHGGEKYASSVLIDDEVMKALEDCVKLAPLHNPPNIIGINACRELMPKTPMVAVFDTAFHQTLPDYAYMYPLPYELYEQNGIRKYGFHGTSHRYVSSVASEMMGKDLKDLKVITCHLGNGASLCAVKEGKSVETSMGFTPLAGLAMGTRCGDIDPAILLFMERELKMSPDEVDTVINKKSGVLGISGVSSDFRDIEGAAEEGNKRAKLALDVYHYTVRQTIGAYTAVLNGVDAIVFTAGLGENSAASREEILNGLEYLGIKIDAEKNKQRGKQIEISTEDSKVKVFVIPTDEELMIARDTKEITAK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMT2_LOCMI
Sequence: EGDFTPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Locustamyotropin-2, Lom-MT-2.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_NEPOL
Sequence: MVEALLSGIVLGLIPVTLAGLFVTAYLQYRRGDQLNL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RUVB_RHORT
Sequence: MAGHEEEDERLISGRRREGEVDAALRPQSLADFVGQRQTRENLGVFVQAARARGEAMDHVLFHGPPGLGKTTLAQIVARELGVGFRGTSGPMIVKAGDLAAILTNLEPRDVLFIDEIHRLNPAIEEVLYPAMEDFQLDLIIGEGPAARSVRIDLPPFTLVGATTRSGLLTTPLRDRFGIPLRLDFYETDELVQIVTRGSRLLGMALTDEGAREVARRSRGTPRVAGRLLRRVRDFAAVAGRSPVDAFIADAALNRLEVDGRGLDAMDRRYLSRMADHYGGGPVGVDTLAAALAEERDTVEDVIEPYLIQQGFIKRTPRGRMLTAIAWTHLGLTPPAETPPVQPDLWSDAP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HUTP_BACCZ
Sequence: MLLQGTHRIGRMAMLLALADENESPVLSIPKDWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: TPIS_CAMC1
Sequence: MKFLANLKCNHTRASFREYAKILDENLSANDDVSVFAPASAFDEKKHMFRLGAQNFYPCESGAFTGEIGKAMLDEFEIKDVLIGHSERREILNESEEFLRSKFDFAAKNGWNVIYCIGENLSTNESGATKEFLSRQLENIDLGYKNLVIAYEPIWAIGTGRSASIEQIDEVLSFLKTKANVPLLYGGSVNAANIADIAGIKSCDGVLVGTASWDANNFLGLIGAASR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APRV1_HUMAN
Sequence: MGSPGASLGIKKALQSEQATALPASAPAVSQPTAPAPSCLPKAGQVIPTLLREAPFSSVIAPTLLCGFLFLAWVAAEVPEESSRMAGSGARSEEGRRQHAFVPEPFDGANVVPNLWLHSFEVINDLNHWDHITKLRFLKESLRGEALGVYNRLSPQDQGDYGTVKEALLKAFGVPGAAPSHLPKEIVFANSMGKGYYLKGKIGKVPVRFLVDSGAQVSVVHPNLWEEVTDGDLDTLQPFENVVKVANGAEMKILGVWDTAVSLGKLKLKAQFLVANASAEEAIIGTDVLQDHNAILDFEHRTCTLKGKKFRLLPVGGSLEDEFDLELIEEDPSSEEGRQELSH
What is the function of this protein?
Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.
What are the official names of this protein?
Retroviral-like aspartic protease 1, Skin-specific retroviral-like aspartic protease, SASPase, Skin aspartic protease, TPA-inducible aspartic proteinase-like protein, TAPS.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OBG_OPITP
Sequence: MFVDECVVKLQAGDGGRGCISFRREKYEPWGGPNGGDGGRGGDVILLGDDDTNNLVDYKYQPHWNAERGEHGLGKDQHGKDGAHRVLKMPLGTVVIDEATGKPVAEVVEDGQQIVLCKGGNGGWGNTHFKTATTRAPKRANDGHPGERGTYRLVLKSIADVGLVGFPNAGKSSLTCLITRARPRTAAYPFTTLHPQIGIIDYPPDRHGRRRLRLADVPGLIEGASENRGLGHRFLRHIERCALLLVLIDMAGTDGRDPREDYKHLLRELELYDPALLKKPRLVAANKMDVEAAAANLSKFKRRHRTVDVLPLSCLTSEGIELLKKELLKRVTALRGREKVSPRARD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSRP1_RAT
Sequence: MAIPGRQYGLILPKKTQPLNRVLQKPSVFGNDSDDDEASVSESLQREAAKKQAMRQTKLEIQKALAEDSTVYEYDSIYDEMQKKKEENNPKLLMGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLEERAEEEEREKRAAALEARLDVTKQKDLSGFYRHLLNQAVGEEAVPKSSFREARTVIKEEKLRGYPDETNSENRPQQNCALQSGVEEAEENPDADSDSEESCDDGERGDHKVKSRGEEDTGASTKYLKHHKNHTHSRSSSEEGGLSTKYHSRSSQSRGHEHKGGQHQDRQSRDQESCHKDRSHREEKSSHRHREASHKDHHWKRHEHEDKPKGRGQGERQDREWKREKYSSREQEKDRQWNDHDRYSEKEKKGKEKEEHRKARRERCEDGAKYRERKKPEGSGQSSERHRDRRESSPRPRPEDDLLDQERSSKARNTEKDKGEQGKPPRSETSLATKHRLTEERPEKGSQPERPPEAVSKFAKRSNEETVMSARDRYLARQMARINAKTYIEKEDD
What is the function of this protein?
RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
What are the official names of this protein?
Nuclear speckle splicing regulatory protein 1, Coiled-coil domain-containing protein 55, Nuclear speckle-related protein 70, NSrp70.
What is the protein family that this protein belongs to?
Belongs to the NSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles.
Protein: LEUC_MYCTU
Sequence: MALQTGEPRTLAEKIWDDHIVVSGGGCAPDLIYIDLHLVHEVTSPQAFDGLRLAGRRVRRPELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIEDLRVVAEVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTDAGAQWRQAGCSMCLGMNPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAAATAVRGTLSSPADLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ESR2_SPAAU
Sequence: MAVACSPEKDQSLLQLQKVDSSRVILSPVLSSPMETNQPICIPSPYTDRGHDFPTIPFYSATNFSYANPPAISDRPSVHQTLSPSLFWPSHGHVGTTLPLHHLQARPQHGQAVQSPWVELSPLDNVLTSSKSARRRSQENEEGEVSSGGKADLHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQRHNDYICPATNQCTIDKNRRKSCQACRLHKCYNVGMTKCGMRKERGNFRDPQMRRVTRLSSQGRTSGPSVLNGPAVGPLNTPQPPALTSKQLIERIMEAEPPEIYLMKDMRRPLTEANIMMSLTNLADKELVHMITWAKKIPGFLELGLLDQVHLLECCWLEVLMIGLMWRSVDHPGKLIFSPDLSLSREEGSCVQGFLEIFDMLIAATSRVRELKLQREEYVCLKAMILLNSNMCLSSSEGSEELQSRSKLLRLLDAVTDALVWAIAKTGLTFRQQYTRLAHLLMLLSHIRHVSNKGMDHLHGMKMKNMVPLYDLLLEMLDAHIMHSSRLPRRSPQQETVEQCDAPARPHSPGTSGPTNTWTPSCTGGRGEPQ
What is the function of this protein?
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURG_BORA1
Sequence: MSAPTILIMAGGTGGHIMPGLAVAEILRQRGWQVRWLGNPDKMEGKLVPARGIEMAPLRFQGLRGRGVTALLKLPLLLTRALLQARKHMAEIQPDVVLGMGGYVAFPGGVVAALRRTPLVVHEQNAVAGTANRWLARMAKNVLTGFPAVLPGADNVGNPVRADLCDLSSPAQRYADRQGPLRLLVVGGSLGAQALNTVVPQALGNIPPAQRPIVMHQAGAQHLQTLQADYAKAGVQAECVAFIEDMASALANADVLICRAGAMTVAEVAAAGVAALFVPLPHAIDDHQTANARYLSDAQAAWLQPQHVLTAQWLADWLTQRDRTELQAVAARARAHARPDAAAHIADVCVAAARRQS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CC50A_CHICK
Sequence: MAVNYSAKEEADGHPAGGGPGGGATAGGGGAVKTRKPDNTAFKQQRLPAWQPILTAGTVLPAFFIIGLIFIPIGIGIFVTSNNIREYEIDYTGVEPSSPCNKCLNVSWDSTPPCTCTINFTLEHSFESNVFMYYGLSNFYQNHRRYVKSRDDSQLNGDNSSLLNPSKECEPYRTNEDKPIAPCGAIANSMFNDTLELYHIENDTRTAITLIKKGIAWWTDKNVKFRNPKGDGNLTALFQGTTKPVNWPKPVYMLDSEPDNNGFINEDFIVWMRTAALPTFRKLYRLIERKSNLQPTLQAGKYSLNITYNYPVHSFDGRKRMILSTISWMGGKNPFLGIAYITVGSICFFLGVVLLIIHHKYGNRNTSADIPN
What is the function of this protein?
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.  Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.  The beta subunit may assist in binding of the phospholipid substrate.  Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex.  Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes (By similarity).
What are the official names of this protein?
Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane. Apical cell membrane. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Protein: ATPF3_CROS5
Sequence: MLIDWFTIVAQIINFLILVFLLNRFLYKPIVKTIKARQQEIENRWQDAEKEKKSAKNEANSYQKKQQELEEKKQEIMIQAQTKADEKYDNLVEEARQDVEQKRKTWDESLEREKAQFFDRFQEKIMQQIYKITGHVLGDLANASLEQQIINQFIHRLENLSEKERENLANSLNTTDNGLIIRSHFEISPESRNRLLSSLQQTHIYQGDNVQFMTNSDLICGIELQASDYKIAWNLKDYVEALEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: OTX2_RAT
Sequence: MTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGAS
What is the function of this protein?
Transcription factor probably involved in the development of the brain and the sense organs.  Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.
What are the official names of this protein?
Homeobox protein OTX2, Orthodenticle homolog 2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TILS_YERPE
Sequence: MNLVTSKPNVLLNPLFAQLGENRHVLVGFSGGLDSTVLLHLLVCLRQQLIPELNIRAIHIHHGLNPQADSWVKHCMQQCDQWKIELKVVRVNIDPRQNGIEAAARTARYQAFSANLAAKEVLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAKMPFAHSQLLRPLLAFSREILENYAQAQQLQWIEDDSNQDDRFDRNFLRLNVLPILNQRWPHFAQATARSAGLCAEQEQLLDELLAENLQQLQGPDRSLSIDGLLQASMAKRAAILRRWLASLGAPMPSQSQLQRLWLEVAMARQDAEPQLMIGTRQVRRFRQHLYLLMPLAEITTNYLPWATVKAAPNSSIIPLLPEPLWLPADLGVLRFVSAGGQAVRPAAVGEEISVRFGLQGDIKIVGRHHSRQSKKVWQELGIPPWQRERIPLLYFGEQLIAAAGVFVTQAGQANENEPCWHLDWDKPLRLG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.