PharMolix/UniProtQA huggingface dataset:
Protein: 1003L_ASFB7
Sequence: MGNRLIRSYLPNTVMSIEDKQNKYNETIEDSKICNKVYIKQSGKIDKQELTRIKKLGFFYSQKSDHEIERMLFSMPNGTFLLTDDATNENIFIVQKDLENGSLNIAKLEFKGKALYINGKDYYSLENYLKTFEDFYKYPLIYNKNK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-3L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: RS5_STRCO
Sequence: MAGPQRRGSGAGGGERRDRKGRDGGAGAAEKTAYVERVVAINRVAKVVKGGRRFSFTALVVVGDGDGTVGVGYGKAKEVPAAIAKGVEEAKKHFFKVPRIQGTIPHPIQGEKAAGVVLLKPASPGTGVIAGGPVRAVLECAGIHDVLSKSLGSDNQINIVHATVEALKGLQRPEEIAARRGLPLEDVAPAALLRARAGAGA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ANMK_ECOK1
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGGRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: URED_STAAT
Sequence: MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQSTIPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLKDNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHLINEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYETISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1012_BACCR
Sequence: MIVTTTSGIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGSYESKLKEARDIAMDEMKELAKQKGANAIVGVDVDYEVVRDGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BC_1012.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: YIHD_ECO57
Sequence: MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELADLTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE
What are the official names of this protein?
Protein YihD.
What is the protein family that this protein belongs to?
To H.influenzae HI_0845.
Protein: RS10_CLAM3
Sequence: MAGQKIRIRLKSYDHSVIDSSARKIVDTVTRAGATVVGPVPLPTEKNVICVIRSPHKYKDSREHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ENV_BAEVM
Sequence: MGFTTKIIFLYNLVLVYAGFDDPRKAIELVQKRYGRPCDCSGGQVSEPPSDRVSQVTCSGKTAYLMPDQRWKCKSIPKDTSPSGPLQECPCNSYQSSVHSSCYTSYQQCRSGNKTYYTATLLKTQTGGTSDVQVLGSTNKLIQSPCNGIKGQSICWSTTAPIHVSDGGGPLDTTRIKSVQRKLEEIHKALYPELQYHPLAIPKVRDNLMVDAQTLNILNATYNLLLMSNTSLVDDCWLCLKLGPPTPLAIPNFLLSYVTRSSDNISCLIIPPLLVQPMQFSNSSCLFSPSYNSTEEIDLGHVAFSNCTSITNVTGPICAVNGSVFLCGNNMAYTYLPTNWTGLCVLATLLPDIDIIPGDEPVPIPAIDHFIYRPKRAIQFIPLLAGLGITAAFTTGATGLGVSVTQYTKLSNQLISDVQILSSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQGGICLALQEKCCFYVNKSGIVRDKIKTLQEELERRRKDLASNPLWTGLQGLLPYLLPFLGPLLTLLLLLTIGPCIFNRLTAFINDKLNIIHAMVLTQQYQVLRTDEEAQD
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: NRIP2_MOUSE
Sequence: MSTGQEARRDEGDSRKEQEASLRDRAHLSQQRQLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPHSVIQRRLVEGNQRRLQGESPLLQALIRGHDSSRTSATQVPALLVNCKCQDQMLRVAVDTGTQHNQISAGCLRRLGLGKRVPKAPGGDVAPEPPTQVEQLELELGQETVACSAQVVDVDSPEFCLGLQTLLSLKLATSLSASSLLPSALGIPTESICDSEALVPHSLLSLPKCTTKSLTEKDLQQMGSRLHPGCRGQSYLLPPLA
What is the function of this protein?
Down-regulates transcriptional activation by nuclear receptors, such as NR1F2.
What are the official names of this protein?
Nuclear receptor-interacting protein 2, Neuronal-interacting factor X 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTNN_CITK8
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTITLGGCEIYTGQLNGTEIALLKSGIGKVAAALGATLLLERCKPDVIINTGSAGGLAPTLTVGDIVVSDEARYHDADVTAFGYEFGQLPGCPAGFKADDALIAAAESCIAKLNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RNH2_SODGM
Sequence: MTESFIYPAATLIAGVDEVGRGPLVGAVVTAAVILDPARPVLGLADSKKLSEKRREALYEEITRYALAWSVGRAEASEIDSINIYQATLLAMQRAVAALAVVPDFVLVDGNRCPLLPMPSQAIVKGDSRVAEISAASIIAKVTRDREMAALHLQFPEYGFAQHKGYPTAFHLEKLALHGATVHHRRSFAPVRRVLELA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_MYCTU
Sequence: MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLNEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR
What is the function of this protein?
Involved in cholesterol degradation.  Catalyzes the conversion of propanal to propanoyl-CoA, using NAD(+) and coenzyme A.  Has a broad substrate specificity, and can also use acetaldehyde, butyrlaldehyde, isobutyrlaldehyde and pentaldehyde as substrates.
What are the official names of this protein?
Propanal dehydrogenase (CoA-propanoylating), Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: COPA2_ECOLX
Sequence: MWIYRSQKSKNPDNLLQLWRVRKDYRGPLKPYSQQFSYAGSIVICPEKFKTSFCARSFCAL
What is the function of this protein?
Controls the copy number in gene replication.
What are the official names of this protein?
Protein CopA/IncA, Protein RepA3.
Protein: RS2_SALTO
Sequence: MAVVTMRQLLESGVHFGHQTRRWNPKMKRFIFTERNGIYIIDLRQTLDYIEKAYEFVRGTVAEGGSILFVGTKKQAQEAIAEQATRVGQPYVNHRWLGGMLTNFQTVYKRLQRMKELEALGDLSGTAAGYTKKETLQLNREKGKLSRTLGGLRDMQKLPAAIWVVDTKKEHIAVDEARKLGIPVIAVLDTNCDPDEVDYPIPGNDDAIRSAELLTKVVAAAVADGLIARSGRRRGTDEKPEAGVATDEPLAEWERELLEEPKKSDEQPAKSDELPVKTDEQPTKSDEQPAAAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NSP2_LOTJA
Sequence: MEMDIDCIHHLDFSGHSTLTNTPSSDNDNYGCSWNHWSPVVNWDAFTGNQDDFHHLIDSMIDDNNTGPAFSDHTASTTSEEEEEEEATTTTMTTTTTTTTTTPEAADDDFKGLRLVHLLMAGAEALTGANKNRELARVILVRLKELVSHTDGTNMERLAAYFTEALQGLLEGAGGAYNSSSKHHVIGGPHHEPQNDALAAFQLLQDMSPYVKFGHFTANQAIVEAVAHERRVHIVDYDIMEGVQWASLMQALASNPNGPHLRITALSRSGVGRRSMATVQETGRRLTAFATSLGQPFSFHHSRLESDETFRPAGLKLVRGEALVFNCMLNLPHLTYRSPNSVASFLTAAKALRPRLVTVVEEEVGSALGGFVERFMDSLHHFSAVFDSLEAGFPMQGRARALVERVFLGPRIVGSLARIYRTGGGGEERGSWREWLRAAGFSGVAVSSANHCQSNLLLGLFNDGYRVEELGSNKLVLHWKTRRLLSASLWTCSSESDCA
What is the function of this protein?
Transcriptional regulator essential for Nod-factor-induced gene expression (Probable) (PubMed:17244637, PubMed:17071642).  Acts downstream of calcium spiking and a calcium/calmodulin-dependent protein kinase required for activation of early nodulation gene expression (PubMed:17244637, PubMed:17071642, PubMed:24329948).  Transcription factor involved in the induction of NIN and ENOD40 genes, which are required for rhizobial infection and early nodule development (PubMed:17244637).  Does not seem to contribute to the early steps of the arbuscular mycorrhizal fungus infection and colonization processes in roots (PubMed:23926062).  Transcription factor involved in the positive regulation of the beta-carotene isomerase D27, which participates in a pathway leading to biosynthesis of strigolactones in roots (PubMed:23926062).
What are the official names of this protein?
Protein NODULATION SIGNALING PATHWAY 2, LsNSP2, Transcription initiator for nodulation.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus membrane. Endoplasmic reticulum. Note=Mainly localized to the nuclear envelope. Also found in the endoplasmic reticulum. Upon Nod- factor application, the nuclear envelope localization disappears and the protein accumulates in the nucleus.
Protein: MZT1_XENTR
Sequence: MANASGSMSAVRETMDVLLEISRLLNTGLDMETLSICVRLCEQGINPEALSSVIKELRRASETLKASESTAS
What is the function of this protein?
Required for gamma-tubulin complex recruitment to the centrosome.
What are the official names of this protein?
Mitotic-spindle organizing protein 1, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1.
What is the protein family that this protein belongs to?
Belongs to the MOZART1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle.
Protein: CYB_CALSW
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISTWWNFGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYSYFETWNIGVILLFMVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFIXPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLIMALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHLAKQRSMMFRPLSQCMFWMLVADLFTLTWIGGQPVEYPFIIIGQLASILYFVIILLILPIVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FOLD_THEFY
Sequence: MTAQVLDGKATAAAIREELKERVAALRARGVVPGLGTILVGDDPGSHAYVRGKHRDCAEVGIASIRKDLPADATQADVEAAVAELNADPACTGFIVQLPLPRGLDENRVLEKIDPAKDADGLHPSNLGKLVLMEEAPLPCTPRGIVELLNRYGVSLRGAEVVVVGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLAAHTRRADIVVAAAGVPGLITKDMVSPGAVVLDVGVTRTEKGLVGDVAPDVAEVAGYLSPNPGGVGPMTRAMLLTNVVEAAERSLS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MMSR_PSEAE
Sequence: MDYIAEPATDMSHTSDWPLPADSLRLPIPAALLEKLAVHPLSRDLYPTSLGHYRRARDHRMSRERHDEHLLIYCSEGQGLLRVREGEAWREYRVGSGDLLWLPPGMAHDYAADDRQPWTIFWTHLRGDSATWLQHSAGYRDTPLRHWGLQHALLGGFEQLLEVRHSGYRFQHFLLAASRLRSLLCQLPLLRPLREGSLDLDGLHAYMREHLHARLELERLAAFCNLSKFHFVSRYKAITGRTPIQHFLHLKIEYACQLLDSSDQSVARVGQAVGYDDSYYFSRLFSKVMGLSPSAYRQRVRQGEGGA
What is the function of this protein?
Regulatory protein for the mmsAB operon.  Activates the transcription of the mmsAB genes.
What are the official names of this protein?
MmsAB operon regulatory protein.
Protein: SYC_RUEPO
Sequence: MTTIKLHNTRTRTKEEFVPIDPDNVRMYVCGPTVYDRAHLGNGRPVVVFDVLYRLLRHVYGADHVTYVRNFTDVDDKINARAAERGRPIGDITAETTQWFLDDMGALGALEPDHMPRATQYIPQMVAMIEELVAKGHAYEAEGHVLFAVDSWKEHYGKLSGRSVDDMIAGARVEVAPYKKNPMDFVLWKPSTPDLPGWDSPWGRGRPGWHIECSAMSYELLGESFDIHGGGNDLMFPHHENEIAQSCCAHPEGHFANFWLHNEMLQVEGKKMSKSLGNFFTVRDLLDQGIPGEVIRFVFLSTHYRKPMDWTEKKAKEAEATLRKWWRLTAPLDEMEIKPSPQFIDALTDDLNTPGAIAELHRLAKEKDYAALEAGLEMLGLQETVNFGVASFGFSTSVEVLEAANDLARRWMAYRDAKNFEEADRLKKSALLAGVDLSVSKEGGIQVPSATINGSPTVDELEALK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_STAAB
Sequence: MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKENPNAIICGIDEVGRGPLAGPVVACAPILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAFGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_MALGO
Sequence: MNNTAHSMSEKVLLVASLEAARYGQYQQAVKGLQAESGLLETHMIDRITDLAYAPPADYFDAVYMMLPSEGVEWAAALPKLRASMIPGAKLRVSVVNENDPSSFLSQVRAELTIAGFTDIQTYENASIESRRPASSSVAEKDSTASSGMGAVKLRRKPNENGGHQQKKALLWATQPETHMDTEAKLQEHARTVSPASRREDCTVDFSAPRTRRKRACKGCTCGLRELEEEDERNSNLVQLDPSEVGGTGGKRTEVTTTVKGPNGEEHTVRRIQVDTRGATSSCGSCFLGDAFRCSSCPYLGLPAFEPGQKVEIPANMDDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: GUAA1_BACTN
Sequence: MQEKIIILDFGSQTTQLIGRRVRELDTYCEIVPYNKFPKEDPTIKGVILSGSPFSVYDKDAFKVDLSEIRGKYPILGICYGAQFMAYTNNGKVEPAGTREYGRAHLTSFCKDNVLFKGVRENTQVWMSHGDTITAIPDNFKKIASTDKVDIAAYQVEGEKVWGVQFHPEVFHSEDGTQILRNFVVDVCGCKQDWSPASFIESTVAELKAQLGDDKVVLGLSGGVDSSVAAVLLNRAIGKNLTCIFVDHGMLRKNEFKNVMNDYECLGLNVIGVDASEKFFAELAGVTEPERKRKIIGKGFIDVFDVEAHKIKDVKWLAQGTIYPDCIESLSITGTVIKSHHNVGGLPEKMHLKLCEPLRLLFKDEVRRVGRELGMPEHLITRHPFPGPGLAVRILGDITREKVRILQDADDIYIQGLRDWGLYDQVWQAGVILLPVQSVGVMGDERTYERAVALRAVTSTDAMTADWAHLPYEFLGKISNDIINKVKGVNRVTYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] 1, GMP synthetase 1, Glutamine amidotransferase 1.
Protein: YREP_BUCDN
Sequence: MERIIEKAIYASRWLMFPVYVGLSFGFILLTLKFFQQIVFIIPDILAMSESGLVLVVLSLIDIALVGGLLVMVMFLGYENFISKMDIQDNEKRLGWMGTMDVNSIKNKVASSIVAISSVHLLRLFMEAEKILDDKIMLCVIIHLTFVLSAFGMAYIDKMSKKKHVLH
What are the official names of this protein?
UPF0114 protein in repA1-repA2 intergenic region.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG4C_XENTR
Sequence: MEASGTDDVEKLKSKFLSAWHNMKYSWVLKTKTYFKRNSPVFLLGKCYHFKYEDSSVTSDGGSNSGSESKEDLSGNVDEFRKDFISRIWLTYREEFPQIETSSWTTDCGWGCTLRTGQMLLAQGLIVHFLGRDWTWTEALDIFSSESEFWTANTARKLTPSLETSFSENNECVSSNKQPLHNCDKKSNSEDFHQKIISWFADYPLAYFGLHQLVKLGKNSGKVAGDWYGPAVVSHLLRKAIEESSDPELQGITIYVAQDCTIYSADVYDLQCNKGTEKAVVILVPVRLGGERTNMEYFEFVKGILSLEFCIGIIGGKPKQSYYFVGFQDDSLIYMDPHYCQSFVDVSVKNFPLESFHCPSPKKMSFKKMDPSCTIGFYCRNAREFEKAAEELTKVLKSSTKQNYPLFTFVNGHAQDFDFVCTPVYDQNDLFTEDEKKRLKRFSTEEFVLL
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine (By similarity).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (By similarity).  In addition to the protease activity, also mediates delipidation of ATG8 family proteins.  Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy (By similarity).
What are the official names of this protein?
Cysteine protease ATG4C, Autophagy-related protein 4 homolog C.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YME2_SCHPO
Sequence: MNLFLSRFTGLRNTSFLGHARPFMFPRRYAHSLVAHNIGHIKLDPNEGLFFVDNLVNTPTYFYIQRYTALLFQNNLKKQLSAAFPSSDTMQLEDIIFRWQDGGAFLKVRYKEFPQDTEAVSEHVRESFRKRPVRTILHPFSTPIPHMVHGIPWLQDLYIFPSRTVDVNFEGPPLSQERLYSIFRTYGKLRSVTINSPTSATLSFSSLRSATSALNCMHGFVYGKTEFHMRYRHMNRFVAFKDWLFSHPRFTIPLVAAAITVLTASLFDPIRKFFVETNIVHGQKLRNINVVGWVKKKTRDIVLSPFHENGTNIKAPIWTTREKDCEQLKEWLDEALHSFIVVQGPRGSGKRDLVDRVVKERKNVLFFDCDRLFSTTNTEMFVSTLASQTGYFPLFSFLNNISSLIDMAAQGLIGQKTGIVSSSEGQVRQILNTTQTVLRSLALREHKEADTSVLDESEFLEVHADRLPVVILDNFQLRKLSNPMQRVVAEWAGNLVKEGIAHVLMLTPDVGGTKSLEQYVNGWENRTLLLGDADPVLAQRYVIESLPEEMQTEELRKELRVQLPKIGGRLRDLDYVARRLRVNSSSVSEAIGGIVSQNASDILQTFLRPASLTSEEKPTFTPEESWTLITYLSQHEYIPYHMLMLDPLFKGHDDAVRALEESELITITTVNARPDKVYAGKPVYVTAFRQLVNDPVLSANMQLVRCNALIGMANNAIKNDEQELQMLKDLGNLESGVKDRAHYLTTRIQKNQGVITDNEKSIERLTEALKKID
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: Y1330_HELPY
Sequence: MLMHSILIILVIILTTYFTRIWPFMVFNAKNPPNDFVRYLGRALSCSVIGMLVIYCFKDIHILKPPYGINEITAFLSVILLHRIFKVFVLSITLPTILYMVLVQSHALEKAFFNP
What are the official names of this protein?
Uncharacterized protein HP_1330.
What is the protein family that this protein belongs to?
Belongs to the AzlD/HI_1737/HP1330 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPF2_BOVIN
Sequence: MDALDRVVKPKTKRAKRFLEKREPKLSENIKNAMLIKGGNANSTVTQVLRDVYALKKPYGILYKKKNITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDIIELGIEKFVSLKDIKNSKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRKMKGLKKRPAERKAEDEENKSKRIKKN
What is the function of this protein?
Involved in ribosomal large subunit assembly.  May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
What are the official names of this protein?
Ribosome production factor 2 homolog, Brix domain-containing protein 1, Ribosome biogenesis protein RPF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RPF2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Associated with the nucleolus in an RNA-dependent manner.
Protein: DXS_BRADU
Sequence: MQTHRAPERPSGADKLEIAVNAYSKTPLLDTIRTPDDLRKLKIEQVRQVADELRQETIDAVSVTGGHFGAGLGVVELTTAIHYVFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRSESDYDPFGAAHSSTSISAGLGMAVARDLSGGKNNVIAVIGDGAMSAGMAYEAMNNAGAMNSRLIVILNDNDMSIAPPVGAMSAYLSRLYSGKTYRTLREAAKQINKRLPKIIANRANRVEEYSRGFMMDGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDMEEGPILVHVVTQKGKGYGPAEASADKYHAVVKFDVATGTQAKAKPNAPAYQNVFGQSLVKEAQKDEKIVAITAAMPSGTGVDIFNKAFPDRTFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQIVHDVAIQNLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNMVIMAAADEAELVHMVATQVAIDDRPSSLRYPRGEGRGIEMPEVGIPLEIGKGRMIRQGSKIALLSFGTRLAECEKAADELAAHGLSTTIADARFMKPLDTELVLKLARDHEILITIEEGSVGGFGSHVAQFLTDQGALDSGMVKFRTMVLPDVFQDHDTPAAMYARAGLDAKGIVAKVFEALGKDVKTETVKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.