PharMolix/UniProtQA huggingface dataset:
Protein: POL_OMVVS
Sequence: SNITAGKQQEGATCGAVRAPYVVTEAPPKIDIKVGTNWKKVLVDTGADRTIVRYHDNSGIPTGRIKLQGIGGIIEGEKWDKVVIQYKEKRIEGTIVVLPSSPVEVLGRDNMAKLDIGIIMANLEEKKIPITQVKLKEGCKGPHIAQWPLTQEKLEGLKEIVDKLEKEGKVGRAPPHWTCNTPIFCIKKKSGKWRMLIDFRELNKQTEDLAEAQLGLPHPGGLQKKKHVTILDIGDAYFTIPLYEPYRPYTCFTMLSPNNLGPCTRYYWKVLPQGWKLSPSVYQFTMQEILRDWIAKHPMIQFGIYMDDIYIGSDLDIMKHREIVEELASYIAQYGFMLPEEKRQEGYPAKWLGFELHPEKWRFQKHTLPEIKEGTITLNKLQKLVGDLVWRQSLIGKSIPNILKLMEGDRALQSERRIELRHVKEWEECRRKLAEMEGNYYDEEKDVYGQIDWGDKAIEYIVFQERGKPLWVNVVHNIKNLSQSQQIIKAAQKLTQEVIIRIGKIPWILLPGKEEDWILELQIGNITWMPSFWSCYRGSIRWKKRNVITEVVEGPTYYTDGGKKNGKGSLGFIASTGVKFRKHEEGTNQQLELRAIEEACKQGPEKMNIVTDSRYAYEFMRRNWDEEVIKNPIQARIMKLVHDKEQIGVHWVPGHKGIPQNEEIDKYISEIFLAREGSGILPKRAEDAGYDLICPQEVCIPAGQVRKIPINLRINLKEDQWAMVGTKSSFASKGVFVQGGIIDSGYQGIIQVVVYNSNDKEVIIPQGRKFAQLILMPLIHEDLEAWGETRRTERGNQGFGSTGAYWIENIPLAEEDHSKWHQDAGSLHLDFGIPRTAAEDIVQQCEVCQENKMPSTIRGSNRRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRIMTIRWYGLFAPKSLQSDNGPAFVAEPTQLLMKYLGITHTTGIPWNPQSQALVERTHQTLKNTIEKFVSMFASFDSAIAAALITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQSTRNQSKFRFCYYRVRKRGHPGEWLGPTQVLWEGEGAIVIKDKNLEKYLVIAKKDVKFIPQPKEIQTE
What is the function of this protein?
During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme.  RNase H activity is associated with the reverse transcriptase.
What are the official names of this protein?
Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
Protein: SYM_METS3
Sequence: MSKIFISCALPYANGPCHLGHIRSTYLPADIYARYNRMIDNDVLLVCATDEHGTPIAVKADKENKKPIEIAKRYHDMIVRDVESMNISLDNFTRTTDDLHYEIAQNFFLELYNKGLIYKKDIQQLYCEKCNKFLPDRYVEGICPVCGSEARGDHCEKCGRALEPTELDEPKCLTCGSTPVIKDTYQYFFKLSEFEDDLKDYIDNNENLPANVRNYAKNWLKEGLNDWVLTRDMDWGIPLPLDEAKGKVLYVWVEAFLGYISSAAQWSRETGIKWEDYWNDTAIHFIGKDIIYHHSIFWPGLLKAYGCKLPDNIYAGEFLSLEGEKMSTSKNWVVWIADFVDKFDPDLLRYYLTINAPLNKDTDFSWDDFQRRNNDELADVIGNFLHRTFTFTHKFFDGEIPEYKNPSAEDNKFKEIIEKLPDTVGEYISDFEFRDGLLEIYRVAKIGNKYFNDQEPWKAVKEDMQKAANCLYLSNQLAKTLAYVLKPYIPNKADAIAKIINLTTPDEWKDAKVPLAEGHKINKAKPLFTKIEDDVINKQKEELQKNLKESEDENMSDLISIDDFDKVVIKIGQVKEAEKIEKSDKLLKLQVDIGDETRQIVAGLAKQYAPEELIDRKVAVVVNLQPAKLFGTLSEGMILATGESAALLSPDECEVGERIQ
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZR2_ORYSJ
Sequence: MATGGGGGGGGMGGGGVGGGAGAAGVGVGGRMPTWRERENNKRRERRRRAIAAKIFAGLRAHGGYKLPKHCDNNEVLKALCNEAGWVVEPDGTTYRKGYKPPERMEVIGCSVSPSPCSSYQPSPRASYNASPTSSSFPSGASSPFLPHPNNMANGVDGNPILPWLKTLSNSPSSKKHPQLPPLLIHGGSISAPVTPPLSSPTARTPRMKTDWDESNVQPTWTGSNSPCVVNSTPPSPGRTMLPDPAWLAGIQISSTSPSSPTFSLVSSNPFSVFKDAILVGNNSSRMCTPGQSGTCSPAIPGMAPHPDIHMMDAVSDEFAFGSSTNGGHQAAGLVRAWEGERIHEDSGSDDLELTLGSSRTRAAA
What is the function of this protein?
May function in brassinosteroid signaling.
What are the official names of this protein?
Protein BZR1 homolog 2, OsBZR2, Protein BRASSINAZOLE-RESISTANT 1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the BZR/LAT61 family.
Protein: SAT_SYMTH
Sequence: MATQIAPHGGRLVDRWLRGPAREEALERARRLPRVRLDAREAADLEMIGDGALSPLTGFMGQADYRSVVAEMRLASGLLWALPVTLAVSRAEAESIREGEEIALEDPGGRLMAVMRVAERFAYDRGAEAARCYGTTDPAHPGVRRLLRQGEVYLGGEVWLLDRPPAPFAEYRLTPAETRAEFARRGWRTVVGFQTRNPVHRAHEYIQKCALEICDGLLLHPLVGETKDDDLPAAVRMRAYEAILEGYFPRERILLAVFPAAMRYAGPREAVWHALCRKNYGCTHFIVGRDHAGVGSFYGPYDAQRIFDHLDPAELGITPLFFDHTFWCRTCGAMASPKTCPHGPEARVALSGTRVREMLYRGEAPPPEFTRPEVARVLMEGLQAAARPQSVET
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: Y1875_STAAM
Sequence: MTKKVAIILANEFEDIEYSSPKEALENAGFNTVVIGDTANSEVVGKHGEKVTVDVGIAEAKPEDYDALLIPGGFSPDHLRGDTEGRYGTFAKYFTKNDVPTFAICHGPQILIDTDDLKGRTLTAVLNVRKDLSNAGAHVVDESVVVDNNIVTSRVPDDLDDFNREIVKQLQ
What are the official names of this protein?
Uncharacterized protein SAV1875.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: PE35_MYCTO
Sequence: MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQLLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFA
What is the function of this protein?
Plays a major role in RD1-associated pathogenesis, and may contribute to the establishment and maintenance of M. tuberculosis infection.  Together with PPE68, stimulates the secretion of IL-10 and MCP-1 from human macrophages, via the interaction with human Toll-like receptor 2 (TLR2).
What are the official names of this protein?
PE family immunomodulator PE35.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: NRDI_RHOJR
Sequence: MTSLVYFSSASENTHRFVQRLGLPATRIPIHDREGTFEVREPYVLIVPTYGGGTTAMGRDTSYVPKPVIRFLNNTHNRSLIRAVIAAGNTNFGESYCFAGNIISQKCHVPYLYRFELMGTAEDVERVRAGLGEFWDHLDDEEHEKWRRPSQTPSTRGA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RL19_THET2
Sequence: MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVIRIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLYFIRNLSDREIRRKLRADRKRIDKDRAAERAAKEEVQKAQEPEASQE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL14_CORGL
Sequence: MIQQESRLKVADNTGAREILCIRVLGGSTRRFAGIGDVIVATVKEATPGGNVKSGEIVKAVIVRTKKETRRADGSYISFDENAAVIIKNDNEPRGTRIFGPVARELREKKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TRPB_CLOBB
Sequence: MDFRTYLKKYPDKNGRFGQYGGAYLTAELIPAFEEIADAYQTICHSSQFINELRRIRKEFQGRPTPVYHCERLSRAIGNCQIYLKREDLNHTGAHKLNHCMGEGLLAKFMGKKRLIAETGAGQHGVALATAAAFFGLECEIHMGEVDIAKQAPNVTRMKILGAKVVPVTHGLKTLKEAVDSAFDSYAKNYKDSIYCIGSALGPHPFPLMVRDFQAVVGYEAKDQFKEMTGFLPDVVTACVGGGSNAAGMFIPFLEEPVDIIGIEPLGRGEKLGDHAASMKYGEKGVMHGFESIMLKDKNGDPAPVYSIASGLDYPSVGPEHAFLRELGRVDYKVINDEEAMEAFFKLSRYEGIIPAIESSHAVAYAMKKAEEMKQGSILVCLSGRGDKDIDYIVEHYGYGEQYFK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MURD_STRPF
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARSVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_CLAMS
Sequence: MAIRKYKPTTPGRRGSSVADFAEITRSTPEKSLLRPLPKHGGRNNAGRITTRHIGGGHKRQYRVIDFKRNDKDGVLATVAHIEYDPNRTARIALLHFIDGTKRYIIAPNKLKQGDKIESGAQADIKPGNNLPLRNIPTGTVIHAIELRPGGGAKMGRSAGASVRLVAKDGPYAQLRLPSGEIRNVDARCRATIGEVGNAEQSNINWGKAGRMRWKGVRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVSPWGQKEGRTRHINKPSDKLIVRRRNAGKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RECF_ACIB5
Sequence: MHLTRLNIERVRNLKTVALHGLQPFNVFYGANGSGKTSILEAIHLLATGRSFRTHIPKNYIQYEADDAIVFAQSATEKIGMQKLASGEQLMKVNGDTVATQGQLAKLLPLQHIDPQSTDIIDHGAKPRRQLLDWLMFHVEPEFYFAWQYYSRALKQRNTLLKTRRNLSLADLEPWNKMLSDYGEILHSQRLSIVEQWNVYFQNDLSQLLPDLEIELEYSPGFHTEQGLMQDLLNQHQKDIERRYTEYGPHRADLRLKTPFGHADDVLSRGQKKLLIIALKLSQIAMLHASNKETVVLLDDLTAELDLTAQQRLIERLSQLGSQVFMTTLDHASVKKHLHDLSISYQLFSVESGQVSLAAP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIQ_SALTI
Sequence: MLKLIDITWLYHHLPMRFTLAVERGEQVAILGPSGAGKSTLLNLIAGFLAPASGTLLIAGEDHTLTPPSRRPVSMLFQENNLFSHLNVQQNIGLGLNPGLTLNASQREKRDAIARQMGIESLMARLPGELSGGQRQRVALARCLVREQPVLLLDEPFSALDPALRQEMLTLVSDICRERQLTLLMVSHSVEDAARIAPRSIVVADGRIAWQGKTDELLSGQASASALLGIKSHIL
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TMA10_YEAST
Sequence: MTRTSKWTVHEAKSNPKYFTHNGNFGESPNHVKRGGYGKGNWGKPGDEINDLIDSGEIKTVFNKTRRGSNSQNNERRLSDLQQYHI
What are the official names of this protein?
Translation machinery-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the STF2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS8_STRPN
Sequence: MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREGFVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLGIAILSTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YAB1_ARATH
Sequence: MSMSSMSSPSSAVCSPDHFSPSDHLCYVQCNFCQTILAVNVPYTSLFKTVTVRCGCCTNLLSVNMRSYVLPASNQLQLQLGPHSYFNPQDILEELRDAPSNMNMMMMNQHPTMNDIPSFMDLHQQHEIPKAPPVNRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSAAAKNWAHFPHIHFGLVPDNQPVKKTNMPQQEGEDNMVMKEGFYAPAAANVGVTPY
What is the function of this protein?
Involved in the abaxial cell fate determination during embryogenesis and organogenesis.  Regulates the initiation of embryonic shoot apical meristem (SAM) development (PubMed:10323860, PubMed:10331982, PubMed:10457020, PubMed:11812777, PubMed:12417699, PubMed:9878633, Ref. 3, Ref. 6, PubMed:19837869).  Required during flower formation and development, particularly for the patterning of floral organs.  Positive regulator of class B (AP3 and PI) activity in whorls 2 and 3.  Negative regulator of class B activity in whorl 1 and of SUP activity in whorl 3.  Interacts with class A proteins (AP1, AP2 and LUG) to repress class C (AG) activity in whorls 1 and 2.  Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems.  Binds DNA without sequence specificity.  In vitro, can compete and displace the AP1 protein binding to DNA containing CArG box (PubMed:10323860, PubMed:10331982, PubMed:10457020, PubMed:11812777, PubMed:12417699, PubMed:9878633, Ref. 3, Ref. 6).
What are the official names of this protein?
Axial regulator YABBY 1, Fl-54, Protein ABNORMAL FLORAL ORGANS, Protein FILAMENTOUS FLOWER, Protein antherless.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBP18_MOUSE
Sequence: MGKGFGLLRKPCQSVVAEPQQYSALEEERTMKRKRVLSRDLCSAWDSPHGLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFVQHDAAQLYLTIWNLTKDQITDTDLTERLQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRFSARNSRTEKICHSVNFPQSLDFSQVLPTEEDLGDTKEQSEIHYELFAVIAHVGMADFGHYCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYTKTGS
What is the function of this protein?
Interferon-induced ISG15-specific protease that plays a crucial role for maintaining a proper balance of ISG15-conjugated proteins in cells (PubMed:11788588).  Regulates protein ISGylation by efficiently cleaving ISG15 conjugates linked via isopeptide bonds.  Regulates T-cell activation and T-helper 17 (Th17) cell differentiation by deubiquitinating TAK1, likely to keep TAK1-TAB complexes in steady conditions.  In turn, restricts activation of NF-kappa-B, NFAT, and JNK as well as expression of IL2 in T-cells after TCR activation.  Acts as a molecular adapter with USP20 to promote innate antiviral response through deubiquitinating STING1.  Involved also in the negative regulation of the inflammatory response triggered by type I interferon.  Upon recruitment by STAT2 to the type I interferon receptor subunit IFNAR2 interferes with the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and acts as a negative regulator of the type I interferon signaling pathway.
What are the official names of this protein?
Ubl carboxyl-terminal hydrolase 18, 43 kDa ISG15-specific protease, ISG15-specific-processing protease, Ubl thioesterase 18.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: RL25_FRATT
Sequence: MANFVLKAEKREDLGTGASRRLRRAGKIPAVIYGGEKEAVSVLLDHDKVLHSTEDKAFFSSEITLDIDGKQEKVIIKALQRHPYKVKLIHADFMRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: CK2N1_BOVIN
Sequence: MSEVLPYGDEKLSPYGDGGDVGQVFSCRLQDTNNFFGAGQNKRPPKLGQIGRSKRVVIEDDRIDDVLKNMTDKAPPGV
What is the function of this protein?
Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity).  Plays a role in the maintenance of long-term retrieval-induced memory in response to contextual fear (By similarity).  Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity).  Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post-myocardial infarction (By similarity).  Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase II inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the CAMK2N family.
What are the subcellular locations of this protein?
Synapse. Cell projection, dendrite. Postsynaptic density.
Protein: HIS7_SOLM1
Sequence: MAKRFGAYSRETGETRVAVEITIDGKGNAAIDTGFGFADHMLNLLAFWAGFDLNLTCRGDLEVDAHHTLEDVAICLGEAFRQALGERVGIERVGDARVPMDEALCDVVVDLSGRPYLVYREDVLPPVIAGEEKDLWREFFKSLAISARMNLHIHFVYGQNGHHLVEAAFKALGLALRRATAAHGSSRVPSTKGSLD
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLR_HUMAN
Sequence: MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSLFT
What is the function of this protein?
Plays an important role in the degradation of dermatan and keratan sulfates.
What are the official names of this protein?
Beta-glucuronidase, Beta-G1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: MTDH_MEDSA
Sequence: MAKSPETELPLKAFGWAARDTSGTLSPFHFSRRENGDDDVSVKILYCGVCHSDLHTLKNDWGFTTYPVVPGHEIVGVVTKVGINVKKFRVGDNVGVGVIVESCQTCENCNQDLEQYCPKPVFTYNSPYKGTRTYGGYSDFVVVHQRYVVQFPDNLPLDAGAPLLCAGITVYSPMKYYGMTEPGKHLGVAGLGGLGHVAIKFGKAFGLKVTVISTSPNKETEAIDKLGADSFLVSKDPEKMKAAMGTMDYIIDTISAAHSLMPLLGLLKLNGKLVTVGLPSKPLELSVFPLVAGRKLIGGSNIGGMKETQEMLDFCGKHNITADIELIKMHEINTAMERLHKADVKYRFVIDVANSFSSL
What is the function of this protein?
Oxidizes mannitol to mannose.  Provides the initial step by which translocated mannitol is committed to central metabolism and, by regulating mannitol pool size, is important in regulating salt tolerance at the cellular level (By similarity).
What are the official names of this protein?
Probable mannitol dehydrogenase, NAD-dependent mannitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: OS9_BOVIN
Sequence: MAAETLLSSLLGLLLLGLLLPATLTGGVGSLNLEELSEMRYGIEILPLPVMGGQSQASDVVIVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMKDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGEVLYLGYYQSAFDWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGRPREAEVRFLCDEGAGISGDYIDRVDEPLSCSYVLTIRTPRLCPHPLLRPPPSAAPQAILCHPALQPEEYMAYVQRQADSKQYGDRAIEGRQDPDPPVWSETKPGVVPPKKAGASPAKENSKESDFWKMLHEPEEQPPEKEETQAEEQEPNLEATDPPPTSPDDFQNNVQVKVIRSPADLIRLIEELKGGTRKGKPNTGQEQPGDSATEVPSREPEMKEKGDPEQQNEVEEEEDDEDEDEDEDERQLLGEFEKELEGILLPSDRERLRAEVKAGMERELENIIQETEKELDPDGLKKESERDRAILALTSTLNKLIKRLEEKQSPELMKKHRKRRVVPKKPPPSPQSTEEDPEHRVRVRVTKLRHGGPNQDLTVLEMKRENPQLKQIEGLVKDLLEREGLTAEGKIEIKIVRPGTEGTEEDARWLTDEDTKNLKEIFFNILVQGAEEAQKERQRQKELESNYRRVWGSPGGEGTGDLDEFDF
What is the function of this protein?
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD).  May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation.  Possible targets include TRPV4 (By similarity).
What are the official names of this protein?
Protein OS-9.
What is the protein family that this protein belongs to?
Belongs to the OS-9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: EEPD1_XENLA
Sequence: MGGNLGCHRSIPKDPSDLCQKSRKYSAACNFSNILVSQERLNINTATEEELMTLPGVTRQVAQNIVEYREYIGGFKKVEDLALVSGVGAAKLEQVKFEICVSSKGGSSQHSPNSLRKDTEYGQHLSAARLNLNTASASQLMNLRGLTQEMVEDIVQYRSQQGPLKSIEDLVKVDSISPSFLDKIRHQVYVQRSRPSSAHTNGGLHFMAKPHPSPTSISLHSEDLDFPPGGPTQFISTRPPVELFGGEREGKPVLRVATWNLQNCSLDKANNPGVREVVCMTLLENSIKLLAVQELSDKDALEKLCTELNQPSLPNIRKWKGMRGSWKCIISEKSLCGPSEKEEYFGFLWDVSAGIELKNVNLSENMQTNGNGKHMYLQPYIAHFKVGTCDLTLVNIHLSPPTVETVKHQNDTYKSAVFGQALQETLKNERDVIILGCFSLPADSSEFDVLRKEKFHCLLPLNTFTNISTKNPQGNKSLDNIWISKSLKKIFTGYSLVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYMDRDCNKKEMATKANGMTVERNDTKHER
What are the official names of this protein?
Endonuclease/exonuclease/phosphatase family domain-containing protein 1.
Protein: Y066_POLSJ
Sequence: MLKYAIIFAVISLIAGALGFGGVAAGAAGIAKILFGLFLILAVIFVVLAALGVGAVRKGMK
What are the official names of this protein?
UPF0391 membrane protein Bpro_0066.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX20A_CTEON
Sequence: ACVPVYKECWYPQKPCCEDRVCQCSFGMTN
What is the function of this protein?
Antagonist of L-type calcium channels (Cav1/CACNA1).
What are the official names of this protein?
U10-ctenitoxin-Co1b, U10-CNTX-Co1b, Neurotoxin Oc M31-11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROQ_HISS2
Sequence: MTEIQKLTNNKEIIAYLAEKFPLCFSLEGEAKPLKIGLFQDLAEALANDEKVSKTQLRQALRQYTSNWRYLHGCRAGAVRVDLNGEPAGILEQEHVEHAAAKLAEAKAKVAERRAVEKANNPKANKKRSVHHSGNKSENKKSAGKKFSNPRQVEQIFVNVDLANLQKGDVVRVKAGDKTTKAEILEVVKEGARVELENGLILTVSADRLFA
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_PSEPW
Sequence: MPTREIRHPLIRHKLGLMRRADISTKNFRELAQEVGALLTYEATQDLPLETYEIDGWCGKVQVEKIAGKKITVVPILRAGIGMLDGVLSLIPGAKVSAVGVARNEETLEAHTYLEKLAPDINQRLALIIDPMLATGGSMVATIDLLKKAGCKEIRAMVLVAAPEGIDVVEKAHPDVQIYTASIDQRLNEHGYIVPGLGDAGDKIFGTKQKDA
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RPOZ_PECCP
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQIQTGGKDPLVPEENDKYTVIALREIEEGLINNQILDVRDRQEQQEQEAAEIQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.