PharMolix/UniProtQA huggingface dataset:
Protein: URE3_STAAW
Sequence: MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPDGTKLITVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_RICRS
Sequence: MSAYKYYDLIRKPIITEKTTTLSEQNKYAFYVDKFAEKLTLKKAIEEIFKVKVKKVNILNVKGKKKRFKGIIGTQINRKKAIVTLEKDHNIDFAGGIK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL16_BACMK
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQALAASWITNRQIEAARRAMTRHMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: BI1_MOUSE
Sequence: MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHVVTHFIQAGLLSALGSLALMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALELCIAVNPSILPTAFMGTAMIFTCFSLSALYARRRSYLFLGGILMSAMSLMLLSSLGNLFFGSIWLFQANLYLGLLVMCGFVLFDTQLIIEKAEHGDKDYIWHCVDLFLDFVTLFRKLMLILAFNEKDKKKEKK
What is the function of this protein?
Suppressor of apoptosis (By similarity).  Modulates unfolded protein response signaling (By similarity).  Modulates ER calcium homeostasis by acting as a calcium-leak channel (By similarity).  Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (PubMed:21926971).
What are the official names of this protein?
Bax inhibitor 1, BI-1, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AIM36_ASHGO
Sequence: MFRRLVTPRLLRLRRQQGLSRPYASKAPGSEDLPSAWKMVGVAVVSTLIFVQAAKSIDRSKPQTEFSEAEFEKVRSGLRRRVTVFKPDELEVLAVLADVPVEKIRAPAGARAVRVQQALERFRTDEHDKYHALLEELHAVHGDDYSAHLPKGALVALMGRYLKEVCQAGDSVVLLGFPRNMQEAIQFESEVAVISALVAPQGSEESQLVQYFKTVNKVITV
What are the official names of this protein?
Altered inheritance of mitochondria protein 36, mitochondrial, Found in mitochondria protein 39.
What is the protein family that this protein belongs to?
Belongs to the AIM36 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: NDHK_PROM1
Sequence: MELNPLKKSPSSEAVRNLREASCGPVGTPTVTNDLSENIILTSLEDLHNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPDPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYLPGCPPRPEAIFDAVIKLRKKVANESISERSKITQTHRYLTIPHKMKRVEAKVNGQYLKAKTQLIALNPSLSEEFDQSLKEVQKISEELSSN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPF1_YEAST
Sequence: MALGNEINITNKLKRQEIFADIKHEKNKERHTMRRKRAKEERENPELREQRLKENVTQTIENTRVYDETINKEVEGDEDDLMRYFNSNSNEPPKIFLTTNVNAKKSAYEFANILIEILPNVTFVKRKFGYKLKEISDICIKRNFTDIVIINEDKKKVTGLTFIHLPEGPTFYFKLSSFVEVKKIVGHGRPTSHIPELILNNFQTRLGQTVGRLFQSILPQNPDIEGRQVITLHNQRDYIFFRRHRYVFKDNERVGLQELGPQFTLKLKRLQRGIKEETEWEHKPEMDKEKKKFYL
What is the function of this protein?
Essential protein.  Required for biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome production factor 1, Ribosome biogenesis protein RPF1.
Protein: CARA_GRATL
Sequence: MTYNLHPAILVLKDGKFYRGWTLINSIISFGEVVFNTGMTGYQEIMTDPSYAEQIITFTYPEIGNTGINHEDNESNKIHVKGIITKNICFSPNNWRQQESFINYIFNNQIPHIFGIDTRALTKHLRKTGSMNGCISSQYLNPYLLSTKFKDRLSIESSDLVKQVTTSKNYEFQGYSHKHFSYLQYKTDKMYGYGLKIILIDFGVKYNILSRLDNYGCSIQILPATSSYETINAYNPDGIILSNGPGDPSIITYAIKTVKKIIKYTNIPIFGICMGHQIISLALEGTTFKLKFGHRGLNHPAGMKQKAEVTSQNHGFAVNQESLYKDTINITHFNLNDTTVAGILHNKKPIFSVQYHPEASPGPHDSDYLFKYFINLIKHFKQYKNYKNSSLAQAR
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYR_HAHCH
Sequence: MNLQQLLEQKISAALHAAGAPEGSPAIVKPSGKPQFGDYQANGVMGAAKALKMNPRELATKVLDVLDLGDMAEKVEIAGPGFINIFLSKDWMSQSLRQVLADPRLTIPLDSPKQTVVVDYSAPNLAKEMHVGHLRSTIIGDAVVRTLEFLGHRVIRQNHVGDWGTQFGMLLAYMNKLKAENQQTLSMELADLENFYRQAKTCFDEDPEFKDSARQYVVKLQSGDQECVSLWKTFIDISLQHCEDVYERLNVSLTRADVMPESAYNEDLPNVIDDLREKGLLTNSDGAECVFMDEFKGKDDETLPLIVKKSDGGYLYATTDLAALRYRERVLKANRVLYFVDARQSLHLNQVYAAGRKAGFVSPDMSLEHMAFGMVLGADGKPFKTRDGGTVKLADLLTEAQGRAYAVVKGKNPEMPEEELNRIAHVVGMAAVKYADLSKNRSSDYIFSFDAMLSLEGNTAPYVQYAYSRVVNVFKKGEVGNLTFEGDLQLAEPIERALAVRLLQFNEILHSVASEGCPHILCGYLYDLSKEFASFYEGCPVLKAEEPVRSSRLMLSLLIAKTLKQGLDLLGIETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10A1_PONAB
Sequence: MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS
What is the function of this protein?
Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation.  In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes.  These changes allow interactions with specific target proteins and modulate their activity.  Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase.  Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole.
What are the official names of this protein?
Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum. Mitochondrion.
Protein: ARLY_STRA5
Sequence: MTKNHKLWGGRFESSLEKWVEEFGASISFDQKLAPYDMKASMAHVTMLGKTDIISQEEAGLIKDGLKILQDKYRAGQLTFSISNEDIHMNIESLLTAEIGEVAGKLHTARSRNDQVATDMHLYLKDKLQEMMKKLLHLRTTLVNLAENHIYTVMPGYTHLQHAQPISFGHHLMAYYNMFTRDTERLEFNMKHTNLSPLGAAALAGTTFPIDRHMTTRLLDFEKPYSNSLDAVSDRDFIIEFLSNASILMMHLSRFCEEIINWCSYEYQFITLSDTFSTGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKSLPLAYNKDLQEDKEGMFDSVETVSIAIEIMANMLETMTVNEHIMMTSTETDFSNATELADYLASKGVPFRKAHEIVGKLVLECSKNGSYLQDIPLKYYQEISELIENDIYEILTAKTAVKRRNSLGGTGFDQVKKQILLARKELKAE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNR_GLOVI
Sequence: MSGLCACTLVGAAQVQQLEAALFAAGMPVEALMEKAGLRLAAAIAADYPAGGYPRVGVLVGPGHNGGDALVVARELWLVGRSVQVFCPRPPIKPLARAHLDYFQSLGGRVHTGAVPEEPGVDLWVDGLFGFGLERPVAEPYAGLMAQVNASGVPVAAVDLPSGLSSETGEALGGLAVRAARTYCLGLWKRGLWQDAALDWLGVPVRLEIGFSEAQVRSVLGEDHRSARLLLPDAARAGLPLARPATAHKYSVGTLLAVAGSRQYGGAATLVALGARSGGPGMLYLALPESLADRVAARLPEAIVHPCPQAENGALADLPGVDLEKFDAVVCGPGLGKAEQALVLRLAREAAGALVLDADGLNLIAGQLEVLAQRAAPTVLTPHPGEFKRLFPDIALADRQGAARTAALRSHAWIVLKGARTVVASPSGQVWVNPGGSPALARGGSGDVLAGLLGALLAQCENPEPAVLGAVWWHAAAGEWLAARHTVLGVDAETLALGLLPFLAADGP
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: TPIS_ECOLC
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H962R_ASFM2
Sequence: MREESWEEHDTIQLTAQRKYLAEVQALETLLTRELSVFLTEPGSKKTNIINRITGKTYALPSTELLRLYEHLEQCRKQGALMYFLERQGTYSGLMLDYDLKLNTNAAPPLESPALSRLCHRIFMHIKNTSVLPEGSHKIHFFFTLKPEVVQGKYGFHVLIPGLKLAASTKKSIIASLQHDATVQKILHEQGVTNPESCLDPHSASVPSLLYGSSKLNHKPYQLKTGFELVFDSSDPDYIPIHQIKNIEAYNLVSELSLTNEQGSLVKPVYCEADIAAEKEEEIPVDDHSLSILMLHDPEARYLHKILNLLPPEYYVEYPLWSNVVFALANTSANYRPLAEWFSQKCPEKWNTGGKEKLEKLWNDASRHTEKKITKRSIMYWAHKHAPQQYKEIVEQGYFSILAEYVYSYNGTLEHYMIAKVIYAMMGNKFVVDVDSNGKYVWFEFVLPGQPMNQGEIWKWRKEVNPDELHIYISENFSRVMDRITEHIKYHLSQPHETNILNYYKKLLKAFERSKSKIFNDSFKKGVIRQAEFLFRQRSFIQTLDTNPHLLGVGNGVLSIETIPAKLINHFHEHPIHQYTHICYEPFNPENPWTKLLLNALQDIIPELDARLWIMFYLSTAIFRGLKEALMLLWLGGGCNGKTFLMRLVAMVLGDHYASKLNISLLTSCRETAEKPNSAFMRLKGRGYGYFEETNKSEVLNTSRLKEMVNPGDVTARELNQKQESFQMTATMVAASNYNFIIDTTDHGTWRRLRHYRSKVKFCHNPDPNNSYEKKEDPRFIHEYIMDPNCQNAFFSILVYFWEKLQKEYNGQIKKVFCPTIESETEAYRKSQDTLHRFITERVVESPSAETVYNLSEVVTAYAEWYNTNINVKRHIALELSQELENSVLEKYLQWSPNKTRILKGCRILHKFETLQPGESYIGVSTAGTLLNTPICEPKNKWWEWSPNPSAPPEKEASAPTP
What are the official names of this protein?
Putative primase C962R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus helicase C962R family.
Protein: RL6_MYCA9
Sequence: MSRIGKQPVPVPAGVDVNIDGQNISVKGSKGTLELTVSEPISVSRNDDGAIVVTRPDDERRNRSLHGLSRTLIANLVTGVTQGYTTKMEIFGVGYRVVAKGSNLEFALGYSHPVLIEAPEGITFAVETPTKFSISGIDKQKVGQISANIRRLRRPDPYKGKGIRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MUTL_BACC2
Sequence: MGKIRKLDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAEEDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTGDAPGTHLIIKGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVSLKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTITGYVTLPEVTRASRNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEVRFSKEQELLKLIEETLQAAFKKIQLIPDAGVTTKKKEKDESVQEQFQFEHAKPKEPSMPDIVLPTGMDEKQEEPLPVKQPAQLWQPPKQEWQPPQSLVREEQSWQPSTRPIMEEPIREEKSWDSNEEDFELEELEEEVQEIKEIEMNGNDLPPLYPIGQMHGTYIFAQNDKGLYMIDQHAAQERINYEYFRDKVGRVAQEVQELLVPYRIDLSLTEFLRVEEQLEELKKVGLFLEQFGHQSFIVRSHPTWFPKGQETEIIDEMMEQVVKLKKVDIKKLREEAAIMMSCKASIKANQYLTNDQIFALLEELRTTTNPYTCPHGRPILVHHSTYELEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: HEM1_BOVIN
Sequence: METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEIGAKPAPRALSTSAVLCQQVTETPPANEKDKAAKAEVQQAPDGSQQAPDGSQQTADGTQLPSGHPSLASSQGTGSKCPFLAAEMSQGGSSVFRKASLALQEDVQEMHAVREEVAQTSVNPSVINVKTEGGELNGLLKNFQDIMRKQRPERVSHLLQDNLPKSVCTFQYDRFFEKKIDEKKNDHSYRVFKTVNRKAQCFPMADDYSDSLISKKQVSVWCSNDYLGMSRHPRVCGAVIDTLKQHGTGAGGTRNISGTSKFHVDLEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDAGNHASMIQGIRNSGVPKYIFRHNDVSHLRELLQRSDPAVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGLQGGGIGDRDGVMPKMDIISGTLGKAIGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILRSTEGRTLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMSYFVDNLLATWKRVGLELKPHSSAECNFCRRPLHFEMMSEREKSYFSGMSKLVSAQA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: BIOB_AKKM8
Sequence: MSLTSSLLSRVLGGGSCSREELIALSREPLEELCQAANAIREHFCGNVFDLCTIINGRSGKCSENCKYCAQSAHYSTAVEEYPLLSDEALLAGARYNDARGILRYSIVTSGKRLTDEDVDRLCASYRHIAEHCGISLCASHGLISKKHCEQLKAAGVSRYHNNLETSRRNFPNVCTTHTYDDKLQTIKWALEAGLEVCSGGIMGLGETMEDRIDMYMDIAALGIKSMPVNFLTPIPGTPYADMTPLGEEEQLRIVALVRFIMPDGFVRIAAGRNTMKDHGRKIFMSGANAAISGDMLTTAGVTIREDLAMLAELGYEVRMK
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SCW4_YEAST
Sequence: MRLSNLIASASLLSAATLAAPANHEHKDKRAVVTTTVQKQTTIIVNGAASTPVAALEENAVVNSAPAAATSTTSSAASVATAAASSSENNSQVSAAASPASSSAATSTQSSSSSQASSSSSSGEDVSSFASGVRGITYTPYESSGACKSASEVASDLAQLTDFPVIRLYGTDCNQVENVFKAKASNQKVFLGIYYVDQIQDGVNTIKSAVESYGSWDDVTTVSIGNELVNGNQATPSQVGQYIDSGRSALKAAGYTGPVVSVDTFIAVINNPELCDYSDYMAVNAHAYFDKNTVAQDSGKWLLEQIQRVWTACDGKKNVVITESGWPSKGETYGVAVPSKENQKDAVSAITSSCGADTFLFTAFNDYWKADGAYGVEKYWGILSNE
What is the function of this protein?
Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.
What are the official names of this protein?
Probable family 17 glucosidase SCW4, Soluble cell wall protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ATP6_PSE14
Sequence: MAEQTASGYIQHHLQNLTFGHLPNGEWGFAHTAAEAKEMGFWAFHVDTLGWSVALGLIFVLIFRMAAKKATSGQPGALQNFVEVLVDFVDGSVKDSFHGRSAVIAPLALTIFVWVFLMNAVDLVPVDWIPQLAMLISGDEHIPFRAVPTTDPNATLGMALSVFALIIFYSIKVKGIGGFIGELTLHPFGSKNLFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLUQ_BURMA
Sequence: MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARVAHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQTQNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLSKQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDARFGPNARG
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: PHIP_HUMAN
Sequence: MSCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQEISPLDSMIQRLQQEQDLRRSGEAVISNTSRLSRGSISSTSEVHSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRKHLTVPKENKIPTVSKNHAHEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIENGSSSSDEGEVVAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGELTENGLTLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTRSIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILENSVKHSKALNTLSSPGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNSGEIIHKKRGRKPKKLQYAKPEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKNRGGRKPKRKMKTQKLDADLLVPASVKVLRRSNRKKIDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW
What is the function of this protein?
Probable regulator of the insulin and insulin-like growth factor signaling pathways.  Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation.  Plays a role in the regulation of cell morphology and cytoskeletal organization.
What are the official names of this protein?
PH-interacting protein, PHIP, DDB1- and CUL4-associated factor 14, IRS-1 PH domain-binding protein, WD repeat-containing protein 11.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMD_METTF
Sequence: MKLAILGAGCYRTHAASGITNFSRACEVAEMVGKPEIAMTHSTITMGAELKELAGVDEVVVADPVFDNQFTVIDDFAYEDVIEAHKEDPEKIMPQIREKVNEVAKELPKPPEGAIHFTHPEDLGFEITTDDREAVADADFIMTWFPKGDMQPGIINKFIDDIKPGAIVTHACTIPTTKFYKIFEEKHGDLVTRPETLNVTSYHPGAVPEMKGQVYIAEGYASEEAINTLFELGQKARGNAYKLPAELLGPVCDMCSALTAITYAGILTYRDSVTQVLGAPAGFAQMMAKESLEQLTALMDKVGIDKMEESLDPGALLGTADSMNFGASAEILPTVFEVLEKRKK
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
5,10-methenyltetrahydromethanopterin hydrogenase, H(2)-dependent methylene-H(4)MPT dehydrogenase, H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase, N(5),N(10)-methenyltetrahydromethanopterin hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the HMD family.
Protein: NUSB_CHLPM
Sequence: MKTYRRQIREKILQALYTLELRDTDIDSAAGWLLTPEILADPKAMKFFNLLLGNIKEHMEEIDRYIAAHTFNWDMSRIAIIDKNILRMAMAELLYCDDIPPKVSINEAIEIAKKFSSTDKSSKFVNGILDAIFNALKEEGKINKNGRGLIDHTPPRAAKTDAKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SYL_STRU0
Sequence: MTFYNHKEIEPKWQDFWAKNHTFKTGTDSSKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTAENIANFKRQINSLGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSVGANITFNVKDSEESFTVFTTRPDTLFGATYAVLAPEHALVDAITTEEQAEAIAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLSSYGTGAIMAVPAHDERDWEFAKQFHLDIIPVLEGGNVQEAAYTEDGLHINSDFLDGLNKEEAIAKTVAWLEEKEVGNEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEDQLPLILPVTKDIHPSGTGESPLANITDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPKNDKAIADPDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKREGSYFHIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEMTGDNSGALDKVYHETVKAVTEQIESMKFNTAIAQLMIFVNAANKEDKLYKEQAKGFVQLIAPFAPHLGEELWQVLTDSNQSISHVAWPTWDENKLVENDVEIVVQIKGKVKAKLVLAKDLSKEELEAAALSHEKIQAEIAGKEIVKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z658B_HUMAN
Sequence: MMNLEKNFDKTTLFNHMRTDKRGKCSDLNEYGTSCDKTTAVEYNKVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTDFTAHQKFYLSDEHGKCRKSFYWKAHLIQHERPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTREKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYKCNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNECGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 658B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.