PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_SORC5
Sequence: MKIHEYQGKQLFARYGVPVPKGEPAFQASEVAPIADRLIAQTGNPVVVVKAQIHAGGRGKGGGVKVAKGGSAEATALAEKILGMQLVTKQTGPEGQKVRRLYIEQGLDIARELYFAMLVDRERRRIAVIASTEGGMDIEEVAHSTPEKIYKLFIDPVLGLAPYQGRQLAIALGLTAKETQRQFLKLVASLYACFTAEDCSLLEINPLVVTGAGDVFALDAKVSFDDNAEFRHADWNGMRDVDEEDPVELQAKRAGLSYVSLDGDIGCLVNGAGLAMATMDIILHYGGKPANFLDVGGGASQEQVKTAFQIILRSERVRGIFVNIFGGIMRCDVVAAGVIAAAKELGLKVPLVVRLEGTNVEAGRKLLDESGLTIQSASSMADGAQKIVAATRGGKAGA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GREA_CLOAB
Sequence: MSQEKKYVITYKGVKKLEEELEYLKTTKRKEITEKIKVALSFGDLSENSEYDEAKNDQAFVEGRIAQIENMLKNANVIDESELKNDVVSVGSKVMVKDYQFDEEIEFSIVGSAEADPIENKISNESPVGSALIGKKVGDEIEVNVPDGVDKYKILAIK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: BFR2_YEAST
Sequence: MEKSLADQISDIAIKPVNKDFDIEDEENASLFQHNEKNGESDLSDYGNSNTEETKKAHYLEVEKSKLRAEKGLELNDPKYTGVKGSRQALYEEVSENEDEEEEEEEEEEKEEDALSFRTDSEDEEVEIDEEESDADGGETEEAQQKRHALSKLIQQETKQAINKLSQSVQRDASKGYSILQQTKLFDNIIDLRIKLQKAVIAANKLPLTTESWEEAKMDDSEETKRLLKENEKLFNNLFNRLINFRIKFQLGDHITQNEEVAKHKLSKKRSLKELYQETNSLDSELKEYRTAVLNKWSTKVSSASGNAALSSNKFKAINLPADVQVENQLSDMSRLMKRTKLNRRNITPLYFQKDCANGRLPELISPVVKDSVDDNENSDDGLDIPKNYDPRRKDNNAIDITENPYVFDDEDFYRVLLNDLIDKKISNAHNSESAAITITSTNARSNNKLKKNIDTKASKGRKLNYSVQDPIANYEAPITSGYKWSDDQIDEFFAGLLGQRVNFNENEDEEQHARIENDEELEAVKNDDIQIFG
What is the function of this protein?
Involved in endoplasmic reticulum to Golgi transport.  Involved in a protein-transport step blocked by brefeldin A, which disrupts the Golgi apparatus and its incoming protein flux.  May also be involved for mass growth or cell proliferation.
What are the official names of this protein?
Protein BFR2, Brefeldin A resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TEG4_EHV1V
Sequence: MDFKYSDTVIHNGVVFYITDGGHRVYFLYGGCLLSVPRPHATAESGEIAKFGLTLRGLTHNDRVVANYVRSELNRTGRHESAPSSEEDVFVDRLEVLAQGAQAFGRDICGSFDLEVYDPYLAECMVSLKVTSGLIVSTGRDIPQDGMLHLYTVPTITNASSGFIYTPNIACFTLVQAYLTELPPELETLISGLFDHIPVARPPLRDESGGHSRTDIIVTSPRAVKTMAIGGTTRCSKRPLRKTVVSDFVQVRLIPKPCSIWDSASRVASGASLQSLQLLFKIADEIILIEEPWPGLDEHLNQARSTIVDAILAVYGNEGKLRFFGGKLTQQGVTTLQRFVLCQFILGKWNLINCYAALEQLAESYIGAVPEARDPLPDPHLVADAVNEIIRESGILGELCEIIVRYTQPTDPVNGSGSEVVELEARLLAEFAANATRVELGLSSYDEVRNMEARIASVLNKLYAKDGIGGAAQVACRILGSGLPVAIVLNVSSITAFDGLDLSRKGAYYLYYLLSERLKRGGVTVHVSRK
What is the function of this protein?
May participate in DNA packaging/capsid maturation events.  Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 homologs into virions.  May also play a role in capsid transport to the trans-Golgi network (TGN) (By similarity).
What are the official names of this protein?
Tegument protein UL21 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae UL21 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: ACM3_RAT
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVKRSSRRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSSILNSTKLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQKDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.
Protein: PROF1_HUMAN
Sequence: MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.  Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
What are the official names of this protein?
Profilin-1, Epididymis tissue protein Li 184a, Profilin I.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS7_SYNAS
Sequence: MPRRREIAKRVILPDPKYKNILVAKFVNNLLKEGKKSIAESILYGAFDLIEKKAKESPVELFERAVNNVKPVIEVKSRRVGGSTYQVPTEVAASRRVALAIRWIISNAKDRAEKTMREKLAGEFIDAANNRGGSIKKRESVHKMAEANKAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: UXAB_ECO8A
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKAKGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: COX3_LUMTE
Sequence: MIRQPFHLVEYSPWPLTSSIGAFTLAIGLASWFHNHGFLCLTLAAFLIIVSMIQWWRDVVREGTYMGHHTSLVTTGLRWGMILFITSEVMFFLAFFWAFFHSSLSPTPEIGCSWPPTGIHPLNPFSVPLLNTAVLLASGVTVTWAHHSLMSGKRIDATQALILTVCLGAYFTFLQAGEYMAAPFSIADSVYGTTFFVATGFHGLHVLIGSSFLAICLARTWSHHFSAGHHFGFEAAAWYWHFVDVVWICLYLCIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL31B_BACC3
Sequence: MKAGIHPDYKKVVFMDTNTGFKFLSGSTKGSNETVEWEDGNTYPLLKVEISSDSHPFYTGRQKFATADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RL11_SALG2
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DX39A_RAT
Sequence: MAEQDVENELLDYDEDEEPQVPQESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPINGQVSVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKNCPHVVVGTPGRILALVRSRSLNLRNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
What is the function of this protein?
Involved in pre-mRNA splicing.  Required for the export of mRNA out of the nucleus (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX39A, DEAD box protein 39, Nuclear RNA helicase, DECD variant of DEAD box family.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: FTSZ_MYCPN
Sequence: MDWIQTAGAGTQLPENNIKIAVFGIGGAGNNIIDDMLRMHPELQTANVQFFALNTDLQHLKTKRYVQNKAVIQFEESKGLGVGGDPQKGAVLAHHFLEQFHKLSDSFDFCILVAGFGKGTGTGATPVFSKFLSNKGVLNLSIVSYPAMCEGLKAREKAAKGLERLNQATDSFMLFRNDRCTDGIYQLANVAIVKTIKNIIELINLPLQQNIDFEDIRSFFKKPAQRLENEANLFRVTNTFTFSFDAHNTIEHFSHKLKNFEYEGFFDHKVEGAQKVILKVLVNQGLYPLDLTQIQEIIWAKIDNHNLEVQLGVDFTDANPSVQLFFLMEKKQAVSSDFIQKPAFISVKEVNQKPAKPFQVLNDLKELGLKYVKQQTGFNY
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: ACCA_RUEPO
Sequence: MTQYLDFEKPLAEIEGKAEELRALARANEEMDVAEEAAALDAKAAKLLDELYRDLTPWRKCQVARHPERPHCRDYVDALFTEYTPLAGDRNFADDLAVMGGLARFNDRPVMVIGHEKGSDTKSRIAHNFGMARPEGYRKAVRLIEMAGRFGLPVVTLVDTAGAYPGKGAEERGQSEAIARSTEMCLRAGVPLVSVIIGEGGSGGAVAFATANRVAMLEHSIYSVISPEGCASILWKNAEKMREAAEALRLTAQDLLKLGVVDRVIPEPRGGAHRDKTAAMEAVRGAIAAMLKELDGKSAEALIKDRRKKFLDIGSKGLAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA1_METPP
Sequence: MMNLQGKKITVHDMTLRDGMHPKRHLMTLDQMKSIASGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHSDEEYLGAVIPLMKQAKVSALLLPGIGTVDHLLMAKDLGVHTVRVATHCTEADVSEQHISKARSLEMDTVGFLMMAHMASPEKLVSQALLMEGYGANCIYVTDSAGYMLPDDVTVRLRAVRGALKPETELGFHGHHNLAMGVANSIAAVDAGANRIDAAAAGLGAGAGNTPMEVFIAVCDRMGIATGVDVFRIQDVAEDLVVPIMDHIIRVDRDSLTLGYAGVYSSFLLFAKRAEKKYGVPAREILVELGRRGMVGGQEDMIEDTAMTLARERAAAAHKAAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: CHED_CUPPJ
Sequence: MRTPHLPEAIATRKYFDREFDRQAIKLLPNEYYVTGEDVVLTTVLGSCVAACIRDEKAGVGGMNHFMLPDDEGGTADRMLSASMRYGCYALEVLINELLKMGARRERLEAKVFGGGAVLANMTTLNIGDRNADFVLRYLKTEEIRVAAQDLRGPHARRVSYFPVTGLALVRRLTRQDDQVSVERDERALARAIATSGTAPSRGGELFTRASASRTPS
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: G6PC3_HUMAN
Sequence: MESTLGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAPAQVHQFPSSCETGPGSPSGHCMITGAALWPIMTALSSQVATRARSRWVRVMPSLAYCTFLLAVGLSRIFILAHFPHQVLAGLITGAVLGWLMTPRVPMERELSFYGLTALALMLGTSLIYWTLFTLGLDLSWSISLAFKWCERPEWIHVDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAQLGNGQKIACLVLAMGLLGPLDWLGHPPQISLFYIFNFLKYTLWPCLVLALVPWAVHMFSAQEAPPIHSS
What is the function of this protein?
Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.  May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis.  Probably required for normal neutrophil function.
What are the official names of this protein?
Glucose-6-phosphatase 3, G-6-Pase 3, G6Pase 3, Glucose-6-phosphatase beta, G6Pase-beta, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphatase family.
Protein: LRAD3_HUMAN
Sequence: MWLLGPLCLLLSSAAESQLLPGNNFTNECNIPGNFMCSNGRCIPGAWQCDGLPDCFDKSDEKECPKAKSKCGPTFFPCASGIHCIIGRFRCNGFEDCPDGSDEENCTANPLLCSTARYHCKNGLCIDKSFICDGQNNCQDNSDEESCESSQEPGSGQVFVTSENQLVYYPSITYAIIGSSVIFVLVVALLALVLHHQRKRNNLMTLPVHRLQHPVLLSRLVVLDHPHHCNVTYNVNNGIQYVASQAEQNASEVGSPPSYSEALLDQRPAWYDLPPPPYSSDTESLNQADLPPYRSRSGSANSASSQAASSLLSVEDTSHSPGQPGPQEGTAEPRDSEPSQGTEEV
What is the function of this protein?
(Microbial infection) Acts as a receptor for Venezuelan equine encephalitis virus.
What are the official names of this protein?
Low-density lipoprotein receptor class A domain-containing protein 3, LDLR class A domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YJU2_DICDI
Sequence: MGERKVISKYYPPDFDPSKVAKIKVKRPTFTKVTTMLPMSIRCNTCGEYIGRGTKFNAKKETVQNEDYLGIKIYRFFLRCKKCAAELTIKTDPKNSEYVCESGATRNYEPWKETDEEKSNRMTKEQEEEQDAMIALENRTLESKREMEMLDALEEIKSLNSRNSEIDTEQLLEYNLQKQELEEKLQDEEDDLLVKSIFNNKNKLELNQINDNNSINNNIDSNKIKRIENDDDDGDKFNSLFSNNNKNNKNIINNNNNNNNNINTTSISNTIETTPTTNQKTSILGNKVKVVINKQEEPIPKNNNNSEPNSFSSFMSAYSDDEED
What is the function of this protein?
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA.  Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.
What are the official names of this protein?
Splicing factor YJU2, Coiled-coil domain-containing protein 94 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family. YJU2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLC_HAEIN
Sequence: MNNMQLKATSPLAEWLSYLEKSHFKPIDLGLDRIKSVAEKLDLLHPVPYVITVGGTNGKGTTCRLLETILLNHGLRVGVYSSPHLLRYNERVRIQNQDLPDEAHTASFAFIDENKTESLTYFEFSTLSALHLFKQAKLDVVILEVGLGGRLDATNIVDSHLAVITSIDIDHTDFLGDTREAIAFEKAGIFRENCPVVIGEPNVPQTMLDQAEKLHCQVARRDVDWLFEQNAENWQWQNKKVRLENLPFCQIPLANAATVLAAVQYLPFDISEQTLRKSLQEVELVGRFQAIKTDKREKLADYLGVPVETLPTIIVDVGHNPHAAKYLSEKLTALKRSIEGKMIAVCGMLKDKDANGVFEHLTPIIDEWHCVTLGGYRGQSGDELVEKLKSHFPNIQATSDNSVMDGVCTALKSAVKNDVVLVFGSFHTVAEFWAVVE
What is the function of this protein?
Functions in two distinct reactions of the de novo folate biosynthetic pathway.  Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu).  Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
What are the official names of this protein?
Dihydrofolate synthase/folylpolyglutamate synthase, DHFS / FPGS, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, Folylpolyglutamate synthetase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: GVPK2_HALSA
Sequence: MEIALDDHDDEDLQSGLTALVVTVVELLVEALEGEAVRRMESGSLSDAEIERLGSQLQALEAELDRLQADQDIEAAVDEFKDDLDHVLRDAITQMSEADSTPGFEPQHSADGDSGGGSA
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpK 2.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: FBRL_CANGA
Sequence: MSFRPGSRGGARGGRGGSRGGFGGRGGSRGGFGGRGGSRGGSRGGFGGRGGSRGGPRGGSRGGPRGGARGGARGGAKGGAKVVIEPHKHDGVYIARGKEDLLVTKNMAPGESVYGEKRVSVEEPSKEDGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKRPNVIPIIEDARHPQKYRMLVGMVDAVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGRYMRSGLKK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: Y055_OSHVF
Sequence: MAESAKTTLQLIFGNLAINIDEEEYQMVWGDVADMRNLFLERVPAKDISEIENLEKKDVKFIVDTLDKVLMSNNLYSLEDPAKNPPSLEELYNPTALLLDKVVTPECGSGYKFLVSLTEEDYTAFLFMMYYLEGFLSEM
What are the official names of this protein?
Uncharacterized protein ORF55.
Protein: LEUD_SOLUE
Sequence: MIPFTNFESRLIKLPINNVDTDQIIPARFLKTTSKVGLDKQLFNDWRQDPDFVLNRPESQGLQILLAGDNFGCGSSREHAPWALTQWGFRAVISTSFADIFKQNSLKNSLLPIEVPADVHAELFSSDGPAKIDLPNQTLTTPSGREVHFEVDQFSKHCLVKGVDELGYILEQAPEIAAYEASHPAPINALA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RS16_BACCQ
Sequence: MAVKIRLKRMGAKKTPFYRVVVADSRSPRDGRFIEEIGTYNPVAQPAEVKINEEAALKWLGNGAKPSDTVRNLFSNQGIMEKFHLSKQGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL28_VIBC3
Sequence: MSRVCQVTGKRPAVGNNRSHAKNATKRRFLPNLQTHRFWVESEKRFVKLRLTAKGMRIIDKKGIDAVLVEIRARGENV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: THIM_CLOAB
Sequence: MLKERLENVRGTNPLIHNITNYVTVNDCANILLACGASPIMADDIGEVEEITSICRGLNINIGTLNENTIESMLKAGKMANKLKHPVILDPVGVGASKLRRQTALKLLEEVKFTVIRGNISEIKVLALGQGITKGVDADVNDKVKDDTLDNVINFAKGFSKKTGAVIAITGAIDIIANESKAYVVRNGNPNMSKITGTGCMLSAMTAAYISANVDSPLEATLASVCAMGICGELAYNRLSKRDGNSSYRNYIIDEVFNLDGDKLDDAARYESY
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: DXS_GEOTN
Sequence: MDLTKIEHPRVVKTMSIPQLKQLSADIRRFLIEKLSKTGGHIGPNLGVVELTIALHREFDSPKDKLIWDVGHQSYVHKILTGRAAEFDTLRQYKGLSGFPKRSESEHDVWETGHSSTSLSAAMGMAIARDLKGTDEYIVPIIGDGALTGGMALEALNHIGHEKTDMIVILNDNEMSIAPNVGALHNILGRLRTAGKYQWVKDELELLLKRIPAVGGKLAATAERLKDSLKYLLVSGVFFEELGFTYLGPVDGHDFEDLLENLRYAKKVKGPVLVHVITKKGKGYSPAENDKVGTWHGTGPYKIETGTFVKTKEGGPSWSGLVSETVRRIARTDPRIVAITPAMPVGSKLEGFASEFPDRMFDVGIAEQHATTLAAGLATQGMKPFLAIYSTFLQRAYDQVVHDVCRQNLNVFFAIDRAGLVGADGETHQGVFDIAFLRHVPNLVLMMPKDENEGQHMVYTALRYDDGPIAMRFPRGNGLGVPLDEELKEIPIGTWEVLRDGSDAVILTFGTTISMALEAAEQLARDGVSVKVVNARFLKPMDEAMLHELLESRLPILTIEEAVLQGGFGSSVLEFAHDHGYHQAVIERMGIPDRFIEHGSVSELLDEIGLTAAHVADRIKTIMPRKQKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.