PharMolix/UniProtQA huggingface dataset:
Protein: TIG_CHLT3
Sequence: MESKFKQLSDTEQELEISFSPDEFQPELDKQYKLAQAKAHLKGFRKGKAPLQMIKKMLGRDIQYQVVEELAGKNFESVAKENDLKLVGQAKIRHYELAENEKLSIYLIYEVHPAFELKPFNEYEFKKAEYQVSDETVEKELKKLLQSKGNMVAVEGAAAPTDIVIGDVQKLDADGTAIVGERQENQSFRLEYMKDDSPFFTALNGVNKGEERRVEVEVKEEDVPEENKKQTFLISVKEIKRMELPELTDELVKELSRGKNETVQDFRDELRKQIEAYFTNKSEEDLMESVAQKFLEENVFTAPSSLIKMYEDMLLDNAKRQIGGAFPPGFDETYYRAEIRPNAEKHARWMLIRNKIAELNGIEVSDDDIKALAEKEAKLTGAEATEEFVNTYFSEQYKPYVIDTLLRDKIYEFIKANTKIEVESKLPEAAV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PYRI_METKA
Sequence: MIVALKVKRIEMGTVLDHLPPGTAPQIMRILDIDPTETTLLVAINVESSKMGRKDILKIEGKILSEEEANKVALVAPNATVNIVRDYSVAEKFQVKPPERVEGFLRCPNPNCITNDEREPVDTVFVRESKKPLEYRCRYCERTVREDQIRELIRPS
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: CDMA_TALVE
Sequence: MTKLPSDASAIKRVEANTSPEQVIELLKQDGVVVLKDFLDQATVQSFREEIKPAIDDFEGGPNFNPDGVKVDIGRGTKHVANLTAISKTYRHDILNNKWMHSILEPLFRPHFGDYWMNRGSVLHIEPGEPAQNLHRDDILYRVTKLRQPGDPDLMINILIAVTEFRDDNGATRFVPGSHVWDDTRGVPTPDQASSAALRPGDALLFVGSLWHGAGSNQSDAFRQGLLLCIHPCHFTPMESHLHVPRTIVESMTPQAQKMIGWRSGITQHDVPIWLAGDHKMEETMGLRSQEVQ
What is the function of this protein?
Dioxygenase; part of the gene cluster that mediates the biosynthesis of chrodrimanin B, a meroterpenoid that acts as a potent blocker of insect GABA-gated chloride channels (PubMed:30417647).  The first step of the pathway is the biosynthesis of 6-hydroxymellein by the polyketide synthase cdmE (PubMed:30417647).  The prenyltransferase cdmH acts as a 6-hydroxymellein 5-farnesyltransferase and produces the hydrophobic metabolite verruculide C (PubMed:30417647).  The FAD-dependent monooxygenase cdmI further converts verruculide C into verruculide B (PubMed:30417647).  The terpene cyclase cdmG then produced the pentacyclic molecule 3-hydroxypentacecilide A, the backbone structure of chrodrimanin B, via folding the farnesyl moiety of the substrate into the chair-boat conformation (PubMed:30417647).  The short-chain dehydrogenase/reductase cdmF functions as the 3-OH dehydrogenase that oxidizes the C-3 hydroxyl group of 3-hydroxypentacecilide A and produces chrodrimanin C, the dehydrogenated product of 3-hydroxypentacecilide A (PubMed:30417647).  The cytochrome P450 monooxygenase cdmJ then accepts both 3-hydroxypentacecilide A and chrodrimanin C and functions as a C-7-beta-hydroxylase to produce respectively chrodrimanin H and chrodrimanin F (PubMed:30417647).  The dioxygenase cdmA accepts chrodrimanin H to afford chrodrimanin E, which is further transformed to chrodrimanin A by the dioxygenase cdmD (PubMed:30417647).  CdmA can also accept chrodrimanin C as substrate to convert it into verruculide A, which is further converted into chrodrimanin T by cdmD (PubMed:30417647).  The last step of the biosynthesis is proposed to be performed by the acetyltransferase cdmC which acetylates chrodrimanin A to yield chrodrimanin B (Probable).  The pathway may also lead to the production of additional shunt products, including chrodrimanins T and U (PubMed:30417647).
What are the official names of this protein?
Dioxygenase cdmA, Chrodrimanin B biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: LPXC_ECOUT
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DCTA_XANAC
Sequence: MHISKPAGPLPASVPFYRQLYFQVVVAIVLGALLGHFEPAFAESLKPLGDAFIKLVKMIIAPVIFLTIVTGIAGMTHLKTVGRVFGKAMAYFLFFSTLALVVGLVVAHVVQPGAGMNINPADLDQSAVKSYVEKSHDLTLVGFLMDIIPNSLIGAFTGDQVVNGKLTGPNILQVLFVAVLFGVSLALVGERGKPVLNLLEALIAPVFKLVHILMRAAPIGAFGAIAFTIGKYGVESLVNLAWLVGSFYLTSLLFVLVILGLVSRLCGFSVLKLIRYLKAELLLVLGTSSSESALPSLMEKMEKAGCEKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNTELTLGHQIALLAVAMLSSKGAAGVTGAGFITLAATLAVVPEVPVAGMALILGVDRFMSECRSLTNFIGNAVATVVVSRWENALDRDRLKLVLDGGEPPLLAPVGQPGVAPASLR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACEK_ECOSE
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ECO7I
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MOAC_ACTP7
Sequence: MNQFTHINTNGEANMVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIENVRLLHKSGGKSGEFNAE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TYSY_MYCGA
Sequence: MKTYLDLLEKVMTKGEVKKDRTNTGTISYFGTQSRYDLREGFPLLTTKKMAWKAICHELLWFLKGDTNIKYLVDHNVNIWNEWPYEAFKKSNDFKGESLQDFVEKIKTDNQFAQQYGKLGPVYGKQWRDFNGVDQIEWVINEIKTNPFSRRLIVSAWNPGEIKEMALPPCHSFFQFFVNEKYEISLQLYQRSGDLFLGVPFNIASYSLLLLMVAQVTGLKPAEFIHTIGDTHIYSNHLEQVKIQLQREPKKLPKVTLNPDIKNIFDFRFEDISLENYEHHDPIKGKVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_PYRHO
Sequence: MVAKGRIIRVTGPLVVADGMKGAKMYEVVRVGELGLIGEIIRLEGDKAVIQVYEETAGVRPGEPVVGTGASLSVELGPGLLTSIYDGIQRPLEVIREKTGDFIARGVTAPALPRDKKWHFIPKAKVGDKVVGGDIIGEVPETSIIVHKIMVPPGIEGEIVEIAEEGDYTIEEVIAKVKTPSGEIKELKMYQRWPVRVKRPYKEKLPPEVPLITGQRVIDTFFPQAKGGTAAIPGPFGSGKCVDGDTLVLTKEFGLIKIKELYEKLDGKGRKIVEGNEEWTELEKPITVYGYKDGKIVEIKATHVYKGVSSGMVEIRTRTGRKIKVTPIHRLFTGRVTKDGLILKEVMAMHVKPGDRIAVVKKIDGGEYIKLDSSNVGEIKVPEILNEELAEFLGYLMANGTLKSGIIEIYCDDESLLERVNSLSLKLFGVGGRIVQKVDGKALVIQSKPLVDVLRRLGVPEDKKVENWKVPRELLLSPSNVVRAFVNAYIKGKEEVEITLASEEGAYELSYLFAKLGIYVTISKSGEYYKVRVSRRGNLDTIPVEVNGMPKVLPYEDFRKFAKSIGLEEVAENHLQHIIFDEVIDVRYIPEPQEVYDVTTETHNFVGGNMPTLLHNTVTQHQLAKWSDAQVVIYIGCGERGNEMTDVLEEFPKLKDPKTGKPLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASKLAEFYERAGRVVTLGSDYRVGSVSVIGAVSPPGGDFSEPVVQNTLRVVKVFWALDADLARRRHFPAINWLTSYSLYVDAVKDWWHKNIDPEWKAMRDKAMALLQKESELQEIVRIVGPDALPERERAILLVARMLREDYLQQDAFDEVDTYCPPEKQVTMMRVLLNFYDKTMEAINRGVPLEEIAKLPVREEIGRMKFERDVSKIRSLIDKTNEQFEELFKKYGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RRF_ALISL
Sequence: MINEIKKDAQERMEKSVEALKNNLLKIRTGRAHPSLLSGLSVEYYGARTPINQVANIIAEDSRTLAITVFDKELAGLVEKAIMMSDLGLNPMSAGTVIRVPLPPLTEERRKSLVKIVRGEAENGRVAVRNIRRDANGDIKALLKDKEISEDDDRRTQDEIQKLTDIAVKNIDDVLAVKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH032_ARATH
Sequence: MYAMKEEDCLQTFHNLQDYQDQFHLHHHPQILPWSSTSLPSFDPLHFPSNPTRYSDPVHYFNRRASSSSSSFDYNDGFVSPPPSMDHPQNHLRILSEALGPIMRRGSSFGFDGEIMGKLSAQEVMDAKALAASKSHSEAERRRRERINTHLAKLRSILPNTTKTDKASLLAEVIQHMKELKRQTSQITDTYQVPTECDDLTVDSSYNDEEGNLVIRASFCCQDRTDLMHDVINALKSLRLRTLKAEIATVGGRVKNILFLSREYDDEEDHDSYRRNFDGDDVEDYDEERMMNNRVSSIEEALKAVIEKCVHNNDESNDNNNLEKSSSGGIKRQRTSKMVNRCYN
What is the function of this protein?
Transcription factor required for MONOPTEROS-dependent root initiation in embryo.  Transcriptionally controlled by MONOPTEROS.
What are the official names of this protein?
Transcription factor AIG1, AtAIG1, Basic helix-loop-helix protein 32, AtbHLH32, bHLH 32, Protein TARGET OF MOOPTEROS 5, Transcription factor EN 54, bHLH transcription factor bHLH032.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PA_CROS8
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVENVQGETQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTMEDFLQPGSQQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPQSGNTYSINEGNYIKFPMGVKKYIKYCQEEDKATQRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPEGKLRLLYECNPMAFLAEQAGGKASDGKQRILDIKPDSLHQRRPFFVGTEQMVNDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WETA_GIBZE
Sequence: MPMASWTLPYRVEAVDRDPGFYWQEIEDGHNNDGSADFFGQFINFDSEIPSSMADHHGHNPGMPTLADGLMLDHPSESTASASSGVSTTEDEFDLFSCSSQVDATVPSQPGSSAAPGASHDVDPRSLALADSSGLMVEKHSMVPRVSMSDPELPRVDGISLQSSPGRRVPVSQPSSPTPPNTMTRKPNKFVEALSSTIRKASKLRKPRKPIAMDRPGSPTMDNPPRALRLQHHEYNGNDVFPPSPTTCGPDSTNFVHGFCDDPFDEIPQQHPNNMRFFKTNGIHTPAESPGIKTEPGMYQPEMAGQAVWPHQQHPHPHPHPHHPQAHTHPHPHPHPHPHQQAVAGHPQHAVPVVGPAPETWPGHEYMAQNAHQSGWWDLNLLNQNGEYVVVDPQQQKNANLNLAMHAQHAELPYEYQVHDPNSAGLMIHMPQPRNDSTPAHDLALNAQTYLPPPPPIPPTTERHRPPRAPSSGARHLSCSPIRKTRQPSIPPTPTTVHSRHSSNGSVASARSASGRGMVPGTPTAMRKQRRSRDSSGGSVGDIGFVNFTPSDGGLLMTGVAPSGSSKTKARREREAMERRRRLSEAAMKAVQAAGGDVDKLMEQGFAF
What is the function of this protein?
AbaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Functions to maintain conidial dormancy by suppressing microcycle conidiation (PubMed:24186953).
What are the official names of this protein?
Developmental regulatory protein wetA.
What is the protein family that this protein belongs to?
Belongs to the wetA family.
Protein: NTH_ENCCU
Sequence: MGSASGEEREGPLGLYLEIKMQRKDIVSPVDTMGCSITPSCRTEEERRFHILVSLLLSSQTKDEVTYEAMARLRKLLPESAATDGEARGGLTIERVANSDVKHINECIKKVGFHNRKAANLKKIAEILREKGLPREMKDLISLPGIGNKMALLYMSHACNRTVGISVDTHVHRISNRIGLVRTRDVESTRRELERVVPRKEWKTINNILVGFGQTICVAKRPRCEECCIRGRCPSSLF
What is the function of this protein?
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage.  The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site.  The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination.  Primarily recognizes and repairs oxidative base damage of pyrimidines.
What are the official names of this protein?
Endonuclease III homolog, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase, DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: PYRG_BUCBP
Sequence: MKKRFIFITGGVVSSLGKGITTAALAAVLEARNLNVTIIKLDPYINIDPGTISPEQHGEVFVTEDGAETDLDLGHYERFIRTKMTRKNNFTTGSIYSEVLNKERKGEYLGATIQIIPHITNTIKKRIISCAHNVDIVFVEVGGTVGDIESLPFLEAIRQIAIDIGRENTIYIHLTLVPYISITKEIKTKPTQHSVKELLSIGIQPDILICRSQYTIPIQARSKIALFCNVLKESVISLINVDSIYKIPKLLNLQKVDQIICHHFKLKVPPADLSEWDEVIYNELNTNNVVTIGIIGKYIKSPDAYKSVIEALKHGGIKNKTVVKIKLINSEKIEKNGTNRLNCLHGILIPGGFGHRGITGKLITVEYARINNVPFFGICLGMQIALIEFFRNVIGLKDANSTEFSQNCQHPIISLIPKGNRNLPNINNNVKKKLGGTMRLGNQTCYLKQDSISHKLYGKNIISERHRHRYEVNNKFINKIEKYGLKITGKSKKNKLVEIIELSNHLWFIACQFHPEFTSTPRDGHPLFIDFIKAAIQYKKIKQK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y1222_PYRFU
Sequence: MVKTITISDDVYNELLRIKGNKSFSEVLRELLKERKGNKEVLKRIFGILSEEEYQEVKKRLKELEGEFEKWEQSLTQM
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Putative antitoxin PF1222.
What is the protein family that this protein belongs to?
Belongs to the UPF0330 family.
Protein: MAD1_YARLI
Sequence: MSDTPSSPFIEHPETPRKALFSSNRPSPVRSTHATPSLHGTPSTASRFSRTPREDVIGLKKTISQLRYDLEALKQEQQVAQILQEEKERELEAKHKKELDRAEQAESDQVFLFNKQKELSDENRTLKEELRSLQSQHEADGRELNHELEGLKDLLNDLQSENRALVSEMNYKIEDYEHRIKAASTTTDDLLKEVENRGTALTEAKMNVVKFEQLVESLKGESLDLKQSAKDLEAVEQTKSQLSDQIKYSRELEAKVSALTVRVEAAESAQQLSQVYEEDLSSMKGKLKNMEGLRQQLAEQQLQILVHEENSAKWKAYLEKSDEFKTVEEVVTALNKARMEKASLLERAGSGVNDETRSTAEAYARLQERVTTLESELQLAQNQLKTEKKKVATSIRQHTLAANEAKFLREQLKAYDDEEVTAAGADVKQGRIDELEKLLEAVKNEKSVLEGELKEARSEQGCTVAAGTKRPRADDSVSSEVISEYTRKLQTLQQEFDEVSVEARLLAKTKEALEARLESLEKSQESRVRILELRENPTSRHEAVKQSMLDTLKAENEALMGKNENSKSVPQASLERKQLELQGVRDKLASTEKSYQRLKEVFSVKSLEFREAVYALTGYQIDILRNKKVKVTSMYAQSDEDSFTFLPDPNHKGQFAGVIDSPLTDEFSNIVDYWVKDKKDFPCFLAALNLELYERKENNGNQAS
What is the function of this protein?
Central component of the spindle assembly checkpoint.
What are the official names of this protein?
Spindle assembly checkpoint component MAD1, Mitotic arrest deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the MAD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_METHJ
Sequence: MANIKAGKERTKIFGRGSHECLLCGRKQGLVRRYNIFFCRQCFREWAPKMGFKKLN
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RS18_DESHY
Sequence: MKRERGRRPRKRVCSFCVDKVESIDYKDTHKIRKYITERGKILPRRISGNCAKHQRQVTVAIKRARHIALLPYIVE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MURG_ECO57
Sequence: MSAQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TOR_TRYCR
Sequence: MSPSLVSDTQKHERGSHGVKIKHFSPYIAVCVTTFSLAFCCFMVHGAITRQPTHLLPFFFIQVFDLIICLIHILGFMSSTSDIRLVIHTKTGPIYIKSTGLTFIILSISRMMLAFKAYCLGMVWDCYKYLMLNRRGNLLDDWYSDQWGHLSTFWSLLRTGRNRGNNSIGNSGSPNEPNTRPRPDTITYDPANDLPKYEDILKIPANAYTPPPYYCSNTNGNVNTTTTDAVTTNTTITSATTVNATTTITTNANTNTSTTTSVISPLTTTNKDDTQINNASSNAHSSC
What is the function of this protein?
Cell surface receptor that binds to human complement C2a protein.  This results in inhibition of the classical and lectin pathways of complement activation, probably due to interference with binding of C2a to C4b and interference with cleavage by C1 or MASP2 such that C3 convertase cannot be formed.  This infers resistance to complement-mediated cell lysis, allowing parasite survival and infection.
What are the official names of this protein?
Tetraspanning orphan receptor, Complement C2 receptor inhibitor tetraspanning, Complement C2 receptor inhibitor trispanning, Complement inhibitory receptor, Trispanning orphan receptor, Tc-TOR.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located on the surface tegumental plasma membrane of metacyclic trypomastigote so in contact with host blood plasma.
Protein: CYB_MUNVU
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVAHICRDVNYGWIIRYMHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFXPYYTIKDILGALLLILFLMLLVLFMPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIXSILILILMPLLHTSKQRSMIFRPLSQCLFWILVADLLTLTWIGGXXVEHPFIIIGQLASILYFLIILVLMPMISTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNT_XYLFT
Sequence: MMNQSITPPTHPPMSQRFRGYLPVVVDVETGGFNWNHHALLEIACIPIEMDDTGRLYPGEVTSTHVIPAPGTDIDPKSLEVTGIILDHPFRFAKEEKLALEHIFTPVRTTMKKYKCQRAILVGHNAHFDLNFLNAAVTRTAYKRNPFHQFSVFDTVTLAGMAYGQTVLARAVQAAGLDWNAADAHSAVYDAEKTAHLFCTITNIWPLMVAG
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: RR19_RHDSA
Sequence: MTRSLRKGPFVASHLAKKVDAAVASNSNNIIKTWSRSSTILPTMVGLTIAVYNGKQHVPVYVSDQMVGHKLGEFSPTRTFRSHVKSDKKARR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: H2A21_CYRHA
Sequence: MKMTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.21, HNTX-II.21, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.