PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_STAAC
Sequence: MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RISB_STAAN
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SP8_XENLA
Sequence: MLAATCNKIGSPSPSPSSLSDTSGSFGKGFHPWKRSSSTSSSCTLASGSLSGFSVGGSSRSANGSSSSSAAAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSGGSGGSGGGGSSGSMSAASPFANEYSVFPVSGGSQEAAAAAAAAAAAAAAAASHHQPVFLSKVHASVDGLQSIYPRVGMAHPYESWFKPSHPGEVSAAAAGGASSWWEVGAGWIDVQSPGAGAALHPGALQGSLHSPLGGYGTDYSAAGLGHFSTGGGGGVGSGGGAAGTGSGGGGGGSHLLSPGGQHLMDGFKPVIGPGSYPDPSSSPLSAGSMLAPTGPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSVGGGSTGSTGPGSGSKKGSDTDSEHSPSTSPTCHSPDLLHPPDRNGLE
What is the function of this protein?
Transcription factor which plays a key role in limb development.  Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
What are the official names of this protein?
Transcription factor Sp8.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIN13_CAEEL
Sequence: MDEFELFQQLNQTAPLVKTEEPEVPDEFQQANNNQSAPLRTGLSDLSHEIAAAKQREEEEAQRLADFMQKDMKEPAVKRKRGSEEYKKDPLESKAPLSTFGHSSRPRRSVNYASIERGDEAQAQSLVTDFGSRGNRKKPKRTRDELDENYMEENEGNSGRKKKPNAKGASRQFQVPGLPTYASQYSRPPKQEDVFKTIVPLAEDARAEGERVIGFRLDSQPAVRRASGGFRRFCAWLSDNQIFSIMQTVDKLCIVGANNEDHDEILLKSIRHVYNAMPPTFRRDWEYAARKDVFDSRLFVQNMPMPLSEISVTDPRHPPSPIARGTTVRPNCCENQPLFLNMCETIEHYLGHHDVVHLFGCDICYRVYPSRYELTKHDCKEFAEYLRQLTFKQQTLHLEAAYMYLCCSQCGLWLSVKPSGEGKKGWTYFATALMNHSCQPLVPVVAYFPKPLKDEGKGIRIQFQVMSELNIGLPLSCSECNIEEFHSVVEIEEHFKEKHEANHTCIKCGKTFGTEFMLKHHAQSHTTQTAQFANYLQMSATYQPPPSSGRLPYVGFGSSIPAIGGLTSGEVQALEASENKKSEFVEPDEYTIRKKLLRWKHAKTKKENRNITDSNEKEFSYEPGESSGEEDFQKSLLEQDNQSSSSSDSDSDSDDFTSSKQKKKRNIKIRGDLGYEHINRNKFFERPESEKEARKRIEKVYKKHVLLSRERLLDPEEALRILEESRMVHLNSIQSTLADDIAMSCIRTISLPASNCIDPLKDLLLVNKIFYFCTKCNYIFSKDPVVHCLSCEVTEDDLIEVYHAASGPHAGVRCIDPECKAHLCSVISLKTHLSDVHSKQATLELVSGELDNFSENRFDRSLMLMAKHFTQLQFDERTYLARFTDIECFMPFSGLLEAKDQPRPMPIRQQPQQIKPAYSLVRPDIIAPNELMRPYTLTPAIRPGQRIKPYKVPRTSRWYSCSWCDREYESLNQFVDHLTRFHTHPCPSCGKAFSSQNTRRTHVCSRLFAEIKGRGATLCGQCPSCPEIHQVERIFVHMLNRHFSTIEYVLATGELLPPARDVGIRYNHGENGGYGRSYESLRAIEQSVVDPRSPDYRLKQVKISALPIHGVELNRLPARDPPMGSFTVCPPKDKNIDPRLMCYMCELTFDSYDELTHHMDDHPEKWANCPFCAANTPTHFDLQKHLIQEHVVQISGQACCAFCQEHHRFMSSHILFRCKRVSRCTICGVKSNDPLANRVHIQRSHALTLRRFQCAYCIKVFVSVGEYYEHECASGGGRVYSCTCSPNKFFNSPIEFCDHFDSVHILRNKCQLCSYDAPSQDGMVKHRKTHMRSGCPKEQTKKLFILMKCLFPKHNSGYMRFIEGGPVPASYQDVDRSQMNYLMCNMGTVSPSCHKSYAQAPRTLLEALEGVASDSRSGGLQKVVNVTTRMNEPSSSDVIMLSDDEDDDCVVFEKAVPNGVAQGSSTSTPNPESSINCEVRVETSQAGYGGAQQPGYVDEDDTDLEVAQGGKSPYGEPVVKEVVDENGDDELAVVAEVENSTGTLPSSISAGREKKFKCQKCSLAFYTNGSLESHMRDHRQDAGAQLCTETYGIPVVTKASWLCRNCCVVFENQPKYQKHMAIHGDTCLTCIHCSGIAFNHTAIQNHMKSHEEKKVRYSCGTCLCTFASDLALFDHLSVAHGVSLYYFCKVCGFGSTSADSVFQHISIHNGHNYSLVQRFGACPAQLLNYDPTDELEFRSQILNKTIQLVSPSDCSHRSMLLQCETVVSCKTCHCTQAWFNYMAFNNHSEETGFPQFKNVDLANDYRRDFPLSRHLNERNALSMSQFGNAKHGSANHSHGQAQPNKRTFRHEVPYRTAAPRSSLQTNGSSMGSVTTNGGRVVRPSPPNSMNVTLRRAPPQQAPPRRIVIANSAPNNTNVLRNHVAVTTKCQFKDCDKVLHSEFDRQLHSMHSSNSSWFCRQCGHSPKSEIDLFLHYIQVHLKPAYDKHQSNSFKSNVFHLKCPIRSCTSPEFQSPKAFEKHMRTAHAAELPFEASCCDARFASKALCVKHDQEHASFLDSNGTDASCCPICGSLSMWSLPKDPHTDCLQSHIIRHGLDYRSSCRQCLKQFPADVNQDQVIAHILDTHGMSMHGNTFHCNLCTTGTKTVEEFAEHCRKAHVFHILVKSSHSTRGELVVTTGQEYENYVGLKSVTRASLNSISSQRASNAGETAQPSVLCAGSGNAALLTIAAAIGEPETSNNTAEVLTLD
What is the function of this protein?
Involved in repression of vulval fate, possibly by a tumor suppressor protein Rb-mediated mechanism (PubMed:10880475, PubMed:16890929).  May act in a common pathway with retinoblastoma-like protein homolog lin-35 and hpl-2 to influence the ER stress response in the intestine (PubMed:24715729).  Plays a role in recruiting chromobox protein homolog hpl-2 to specific chromatin sites (PubMed:16890929).
What are the official names of this protein?
Zinc finger protein lin-13, Abnormal cell lineage protein 13.
What are the subcellular locations of this protein?
Nucleus. Note=Localization to nuclear foci overlaps partially with chromobox protein homolog hpl-2.
Protein: EXOS2_MOUSE
Sequence: MALEMRLPKARKPLSESLGRDSKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYNGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKDEDAGGFIANLEPVALSDREVISRLRNCVVLLVTQRMMLFDTSILYCYEASLAHQIKDILKPEVMEEIMLETRQRLLDQEG
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7 (By similarity).
What are the official names of this protein?
Exosome complex component RRP4, Exosome component 2, Ribosomal RNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: SLS3_TRYB2
Sequence: MAVPPVEMYSGSFWNRMRKPLPLRTQVIRFTVVFVIVSFILAVALQITHERMPDPKVTKPLPDLGFELLTKVPGMYVLADCCIGFLNILSVFTAFKLYLLHRHCVGSGEPELPCNIPGVSRFFLSVWLCKENCRIELRNVHTIAWIRFITSYALLLLFRSVVIVMTSFPAPDDLCQNPPKIENPVKNVILTVLTAGGGSIHCGDLMYSGHTVILTLHLMFHWIYGAMVHWSFRPVVTVVAIFSYYCIVASRFHYTDDVLVAIYLTIATFIAVGHNADGAPWQLQLFIRWWPCCGANSREMTEDSQPVMVAFKSEAAGQSSRKVVDERNH
What is the function of this protein?
Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa.  Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors.  Directly and specifically recognizes the choline head group on the substrate.  Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate.  Does not function strictly as a SM synthase.  Essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential drug target (By similarity).
What are the official names of this protein?
Phosphatidylcholine:ceramide cholinephosphotransferase 3, Ethanolamine-phosphorylceramide synthase, EPC synthase, Sphingolipid synthase, Sphingomyelin synthase, SM synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSCB_ECO45
Sequence: MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: ISPF_CLOB1
Sequence: MRIGLGYDVHKLVENRPLIIGGVTIPHDKGLLGHSDADVLVHAIMDALLGAAALGDIGKHFPDSDKNFKNISSLLLLSKVKDLINKEGYKIVNIDCTIIAQKPKMLYHIDAMKKNICKCLKLDNNMLNIKATTEEGLGFTGKEEGISANAICLLD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: BSHC_HALH5
Sequence: MIVEELKLLPSSKAAKDYLNNQNDMLSFFDYNIHQPTVFQQRLSDLQEQPYDRDALSKALLSYQKRFAFHDKAAQQVEKLKDPRSVVVIGGQQAGLLTGPLYTIYKAVTIVLLAREQERALGVPVVPVFWIAGEDHDLDEINAVPIEKNGRWRSHRIEEKRKRIASEAGLNKETLAKWLATVFRSLPETEHTLPLYERVKTLAGRSNTYTDFFAELLLYLFRDEGLVVFDSGDPSFRTLEKSCFHMLIQKTKNVQGAFAHQVKKLEQAGYGRPIITEETNAHLFYVEEGSRYRIDYTGENYELNGKNQTFSREELLEHLTLHPERFSNNVVTRPVMQDALFPVLAFVAGPGEISYWATLKRVFHECGMKMSPVVPRISATCVPSAVQKWFAEKQYSYEEAIAHGLEKEKEGWLEEQTPWPIDQVVEEAITQIRHSHKPIKDLAEQIGETPGKLANKNWSIIESQLRFMERRMKRHVRERFEHELSKFDEAERWLKPNGLLQERHDHVIQLLNIVGDDFIPRLISMNINKMGVHYLVKL
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: NUSB_DECAR
Sequence: MTTFLSDSEHPQDVKAPPKSARRRAREFVLQGLYQWRVGGADEASIEAYAPEMEGFAKADREFFVGTLRGVISQQEKLIEQVSTHIDRPFNELSPVEACILMLGSFEMLNHAETPYRVIINEAIELTKAFGGTDGHKYVNGVLDKVAAILRPDEVAARKQAKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: P2C58_ARATH
Sequence: MAGSNILHKIKLKAGFCGSAPDMGRGKSKMWKNITHGFHCVKGKSSHPMEDYVVSEFKKLEGHELGLFAIFDGHLGHDVAKYLQTNLFDNILKEKDFWTDTENAIRNAYRSTDAVILQQSLKLGKGGSTAVTGILIDGKKLVVANVGDSRAVMSKNGVAHQLSVDHEPSKEKKEIESRGGFVSNIPGDVPRVDGQLAVARAFGDKSLKLHLSSEPDITHQTIDDHTEFILFASDGIWKVLSNQEAVDAIKSIKDPHAAAKHLIEEAISRKSKDDISCIVVKFH
What are the official names of this protein?
Probable protein phosphatase 2C 58, AtPP2C58.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: PSAJ_NEPOL
Sequence: MKDFTTYLSTAPVLAAVWFGFLAGLLIEINRFFPDALSFSFV
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TYSY_FLAPJ
Sequence: MKQYLDLVKYVLNNGTQKGDRTGTGTKSVFGYQMRFNLAEGFPMVTTKKLHLKSIIHELLWFLKGETNIAYLQQNGVKIWDDWADENGELGPVYGHQWRNWNNEEIDQITELIETLKINPNSRRMLVSAWNPSVLPDTTKSFAENVANAKVALPPCHAFFQFYVSEGKLSCQLYQRSADIFLGVPFNIASYALFTMMIAQVCDLQAGEFIHTFGDAHIYNNHFEQVALQLSREPKPLPKMILNPAVKNIFDFKFEDFKLEGYESHAHIKGAVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAAF8_RAT
Sequence: MTSKDKAVVSLPVSPWDAILKAAKDQLPSLDSDSSLSDCEEEEPFIFQRNQPVLIPDLTEELAEDPVGVDESGTWVTAGRSPSPEPLLVPGRLAIEPRSEWMVRSKDLAHQERRGPGWSCQSCVKSSPILLDTKEAPAWPEGRGSQSPPWSSQGEGATFPLEGKLKTEPSDTDFKNSAKRRALRRERRKMIEREILQKVTQAAQNPASGDQGQVAELGPRPKATSEQSWEGRPVLSLKQLEGWDLDYILQSLPGQQGSQGDSASRSAWWLADRCQDQGHSTGPSQDILLEQLALLCATQSRVRHPTWKVSADKLQDTEEQVARTRSASAESGFQTERVQKRAESRRLKTEPPTVFLDLRLTEPSDPQEHQSQESSEHSSSDSEEEEVGSAGSIPVASSWEQRYCTGKSQLLQQLRAFRKGAVPPQLSAKDGPGGQKDQAQEDTGGSQTQRKKHIKLWAEKQNALNLGDPLGTRLLPGMGQL
What is the function of this protein?
In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme.  Interacts with outer dynein arm (ODA) subunits.
What are the official names of this protein?
Dynein axonemal assembly factor 8, Dynein axonemal-associated protein 1, Uncharacterized protein C16orf71 homolog.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: KDGL_SINSX
Sequence: MDAKNTTHRIGQTGPVEKQTGIRHLFAAASYSLGGAKRLIGEAAFRHELIAFAAAMIAFIIVGATFFQYVAMAILFLLMMAFEAINTAIEEIVDRVSPEISEMGKNAKDLGSFACLCLIVANGVYAAYVVIFDGFMN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid.  Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
What are the official names of this protein?
Diacylglycerol kinase, DAGK, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the bacterial diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZPR1_CAEEL
Sequence: MAADSQDIYRNLSADDYEAAPIVVDSVCPVCEEDGETRIMCTSIPYYRAVILMSFECPHCGHKNNEIQSGEAVQEHGTLIVLRVQKPEDLRRQLVKSEYASIEVPELQLEIPHKSQPGEVTTVEGVLERVHRGLSQDQEKRRLLDPEGASQIDAYLQKITSCMELGETWTLRLRDPTGNCYIQNPDVRHVDPRCIISHYHRNLDERKLLALADDNEEEEEVEPSAAAPEFKSYEDAKQEVLHFATDCPNCHGPTEVKMKPTDIPFFQTVIIMSLACDRCGYKSNEVKSGGAIRDQGCRMSVKLEKDLDLARDVLKTDTCALSIPEIDLEVGGNALCGRFTTIEGLLTATKEQLDAQSSFFMGDSAQTGEKSAVTTFLEKLDDIIALRLPATIILDDPTGCSYVQSLTAPMDDPRLTKEFYTRTYEQNDELGINDMKVENYGELDALAEEDEPHEA
What are the official names of this protein?
Zinc finger protein ZPR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZPR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ERB1_HUMAN
Sequence: MDPLHTIEKVPARRNIHDRGHQGHRMGDGTPGRPKISVQQMTRFSLIIFFLSAPFVVNASTSNVFLQWAHSYADGLQQGDPCWVCGSLPVTNTMELPWWVSPLQGKDWVFFQSFIGDLKQWTGAQMTGVTRKNISEWPINKTLNEPGHDKPFSVNETRDKVIAFAIPLLDTKVFVQTSRPQNTQYRNGFLQIWDGFIWLTATKGHLSQIAPLCWEQRNHSLDNWPNTTRVMGWIPPGQCRHTILLQQRDLFATDWSQQPGLNWYAPNGTQWLCSPNLWPWLPSGWLGCCTLGIPWAQGRWVKTMEVYPYLPHVVNQGTRAIVHRNDHLPTIFMPSVGLGTVIQHIEALANFTQRALNDSLQSISLMNAEVYYMHEDILQNRMALDILTAAEGGTCALIKTECCVYIPNNSRNISLALEDTCRQIQVISSSALSLHDWIASQFSGRPSWWQKILIVLATLWSVGIALCCGLYFCRMFSQHIPQTHSIIFQQELPLSPPSQEHYQSQRDIFHSNAP
What is the function of this protein?
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection.  Endogenous envelope proteins may have kept, lost or modified their original function during evolution.  This endogenous envelope protein has lost its original fusogenic properties.
What are the official names of this protein?
Endogenous retrovirus group PABLB member 1 Env polyprotein, Endogenous retrovirus group PABLB member 1, Envelope polyprotein, HERV-R(b) Env protein, HERV-R(b)_3p24.3 provirus ancestral Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family. HERV class-I R(b) env subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=At the origin, this retroviral envelope protein was localized in the virion.
Protein: GWT1_ASPFU
Sequence: MDPDYKARKEAFVSGLAGGSILEINAVTLVASVSVFLWSILQSRLSFFTPYSAAALLVDFLLNVLAILFATTLYSSAPLLLNLLLISPALLILLSTKRPRTPVKAKPPRQSARAGKDDSKHATALPESLPIHPFLTTYRAAMMVITCIAILAVDFRIFPRRFAKVENWGTSLMDLGVGSFVFSGGVVSARSLLKSRINGSKRLPLAKRLIASTRHSIPLLVLGLIRLYSVKGLDYAEHVTEYGVHWNFFFTLGLLPPFVEVFDALATIIPSYEVLSVGIAVLYQVALESTDLKSYILVSPRGPSLLSKNREGVFSFSGYLAIFLAGRAIGIRIIPRGTSFSRSPEQARRRVLISLGVQALVWTTLFVLNSTYAMGYGANIPVSRRLANMPYVLWVSAFNTAQLFVFCLIETLCFPAVHRTTTQESESERVDFATSRIMSAFNKNSLAIFLLANLLTGAVNLSISTIDANTAQAIAVLIGYSSIITGVALALHHANIKVLPF
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
GPI-anchored wall transfer protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL13_WIGBR
Sequence: MKTFMLKKNIARQNWHIFDAKNKILGRFSTKLASILKGKNDITYTPHVDSGNYVIVINSKKIKITGKKLKNKFYYHHTGYSGGIKKISLENMIKNNSELVIYKSVKGMLPKGSLGRVMIKKLKIFSGESHNHEAQKPKKLLT
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: AK1H_SERMA
Sequence: MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDILPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNAAIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIPADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKDSTDADMPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISFCVPQGELQRARRALEEEFYLELKDGVLDPLDVMERLAIISVVGDGMRTLRGISARFFSALARANINIVAIAQGSSERSISVVVSNDSATTGVRVSHQMLFNTDQVIEVFVIGVGGVGGALIEQIYRQQPWLKQKHIDLRVCGIANSRVMLTNVHGIALDSWRDALAGAQEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSHRKFLYDTNVGAGLPVIENLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQARANGYTEPDPRDDLSGMDVARKLLILAREAGYKLELSDIEVEPVLPPSFDASGDVDTFLARLPELDKEFARNVANAAEQGKVLRYVGLIDEGRCKVRIEAVDGNDPLYKVKNGENALAFYSRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
What are the official names of this protein?
Bifunctional aspartokinase/homoserine dehydrogenase 1, Aspartokinase I/homoserine dehydrogenase I, AKI-HDI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the homoserine dehydrogenase family.
Protein: CML28_ORYSJ
Sequence: MDSTELRKVFKMFDKNGDGRITKKELGESFKNFGIFIPDDELDATMDKIDANGDGCVDVEEFGLLYRSILGDDAAGRAPRTAAAAIGGEGGAPDDEDEGMREAFNVFDQNGDGFITVDELRSVLSSLGLKHGRTADDCRRMISMVDADGDGRVDFKEFKQMMRGGGFAALGG
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML28, Calmodulin-like protein 28.
Protein: Y1444_SHEWM
Sequence: MKIWVDADACPGVIKEILFRVADRAKVEVTLVANHSMRIPPSRYINMVTVPSGFDVADDEIVKRLDAGDLVITADIPLASEVIDKGGVALNPRGELYTEQNIKSILNMRDFMDTMRASGVQTGGPAAIGASEKQAFGNQLDRFVTKHHKPV
What are the official names of this protein?
UPF0178 protein Swoo_1444.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: VANG2_MOUSE
Sequence: MDTESQYSGYSYKSGHSRSSRKHRDRRDRHRSKSRDGSRGDKSVTIQAPGEPLLDNESTRGDERDDNWGETTTVVTGTSEHSISHDDLTRIAKDMEDSVPLDCSRHLGVAAGAILALLSFLTPLAFLLLPPLLWREELEPCGTACEGLFISVAFKLLILLLGSWALFFRRPKASLPRVFVLRALLMVLVFLLVISYWLFYGVRILDARERSYQGVVQFAVSLVDALLFVHYLAVVLLELRQLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRRARLVVAVEEAFTHIKRLQEEEQKNPREVMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILQHLEFCITHDMTPKAFLERYLAAGPTIQYHKERWLAKQWTLVSEEPVTNGLKDGIVFLLKRQDFSLVVSTKKVPFFKLSEEFVDPKSHKFVMRLQSETSV
What is the function of this protein?
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate.  Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea.  Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.  Required for cell surface localization of FZD3 and FZD6 in the inner ear (PubMed:16495441).
What are the official names of this protein?
Vang-like protein 2, Loop-tail protein 1, Loop-tail-associated protein, Van Gogh-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
Protein: PR7R_MMTVG
Sequence: MPRLQQKWLNSRECPTLRREAAKGLFPTKDDPSACTRMSPSDKDILILCCKLGIALLCLGLLGEVAVRARRALTLDSFNNSSVQDYNLNNSENSTFLLGQGPQPTSSYKPHRLCPSEIEIRMLAKNYIFTNKTNPIGRLLIMMLRNESLSFSTIFTQIQRLEMGIENRKRRSTSVEEQVQGLRASGLEVKRGKRSTLVKIGDRWWQPGTYRGPYIYRPTDAPLPYTGRYDLNFDRWVTVNGYKVLYRSLPFRERLARARPPWCVLTQEEKDDIKQQVHDYIYLGTGMNVWGKIFHYTKEGAVARQLEHISADTFGMSYNG
What is the function of this protein?
Superantigen.
What are the official names of this protein?
Protein PR73 3'-endogenous.
What is the protein family that this protein belongs to?
Belongs to the mouse mammary tumor virus PR73 superantigen family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.