PharMolix/UniProtQA huggingface dataset:
Protein: MRD1_YARLI
Sequence: MSRLIVKNLPPYLDEAGLKKHFSTVKDPKSAGFAPSDITDVKVVRARDGKTRRFGFVGFRSDETAEAAVKYFDTSFINSTKISVAVAMTFTDPNVPLSSRERKRQAAQRAREDAEDDREAKKARYLEKPMTIDDINGLGNASDPRLADYLDAMQVRSNAKTWANNDAGAVANEPQVIQSTASDDEYDEFTGKGDDEIDEDEDEEEESENKKDDDNEEAEEDEEDPVIEDGLAADPGVSDMDWLRQRQTRIKEGEPEEDRENRHTESKSEGKKGKGNAPKAATPVDEEPSEDPTIVSIRKTGRLFLRNLLYTAKEEDFRQLFSQYGELEEVHLPINTKTGQCKGFAHVQFEDPENAIAAYEAQDGKIFQGRLLHILPGKPKKDYNRLDEHDLKNLPLKKQQELKRKAEAAKQQFSWNSLYMNQDAVMESVAKSMGIKKSELIDPDSSDAAVKQALAEATVIGDVKSYFEKMGVDLASFDNKDRDDRVILVKNFPFGTTQPEIAEMFSEYGDLYKVMMPPAGTIAIVIFKHIPDARAAFAKLAFRRFKTSILYLEKGPKNLLPNEKMESDEVEHVKQDKIVTIEDKLSASDVMDTGSNDERPATASTSVFVKNLNFKTTSRVLTDAFKALDGFLVAQVKMKPDSKNKGKFLSMGFGFVEFSSKEAAEIAQKAMDGHVLDGHKLQLKISNRGQDEETTETKKAIDSKILIKNLPFEATKKDVQKLFGAFGSLKTVRVPKKFNSESRGFAFAEYVSAKEAEHAMSALQGTHLLGRRLVLQYAQADASNAEEEIERMQATVSKQAAQRSFADMKLAGEGKRRVDLEGEDEEEF
What is the function of this protein?
Involved in pre-rRNA processing.
What are the official names of this protein?
Multiple RNA-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y6593_DICDI
Sequence: MLKKKGFSTSFPNEDFIDNQDTISNFKIKKEDFLLDFDDTYEQLNMTTPKGKIIIQGQENHSPFSLKSFSNLSFDYNRPLSPKTHILNIQDNNNNNYSPILKRVNKTISPSLVSSTNRFKNSLSCSSSSPSSSSSSSSSSPRLISTPPIISTPSSPMILTSSLDKFDEILSENEFMSLDNSVTSSSSSPSSSSCSSPIVIKTNATTSTKIVTPSSSPSSSYIEDAPSTPSPSKLFQSLSFKSPCSSPSSSSSSTTTPKSSINGGNIIKKQLFSNKRIQDIKIEKPSTKIDLHPSKLQIKSNLKIKPSLPYNSTEVTANTKTTTSTTTTTNTTIPTLSKNIIKRTSSVGLSPTLSSTQLVNKSSRKSISAATTTTITPHNNNSTMTTKTPSKRSLDTSNLSTPKSTSSTINKAFTTSTTPLKKPRMSMTPLSSSSSSSTTPSKFINPLPSSSSKTTTTITNSKRLSTLSKPSPITPITPTITKTTATTTTTTTTTPNKPTNKRLSTLVNTAQKPRKSYAPPPSSHISDELEQRIQEALLAEANGNYTGGSVLTHSSPQKVEQSEWSPIRKKSTLHDVHACTKKNY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0268590.
Protein: NCOA5_HUMAN
Sequence: MNTAPSRPSPTRRDPYGFGDSRDSRRDRSPIRGSPRREPRDGRNGRDARDSRDIRDPRDLRDHRHSRDLRDHRDSRSVRDVRDVRDLRDFRDLRDSRDFRDQRDPMYDRYRDMRDSRDPMYRREGSYDRYLRMDDYCRRKDDSYFDRYRDSFDGRGPPGPESQSRAKERLKREERRREELYRQYFEEIQRRFDAERPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREKEREEIARQAAKMADEAILQERERGGPEEGVRGGHPPAIQSLINLLADNRYLTAEETDKIINYLRERKERLMRSSTDSLPGPISRQPLGATSGASLKTQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAKILSLFNSGTVTANSSSASPSVAAGNTPNQNFSTAANSQPQQRSQASGNQPPSILGQGGSAQNMGPRPGAPSQGLFGQPSSRLAPASNMTSQRPVSSTGINFDNPSVQKALDTLIQSGPALSHLVSQTTAQMGQPQAPMGSYQRHY
What is the function of this protein?
Nuclear receptor coregulator that can have both coactivator and corepressor functions.  Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2.  Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).
What are the official names of this protein?
Nuclear receptor coactivator 5, NCoA-5, Coactivator independent of AF-2, CIA.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_PECCP
Sequence: MQTSPLLESLMEALRCLPGVGPKSAQRMAFQLLQRNRSGGMRLAQALTRAMSEIGHCSDCRTFTEQDVCAICSNPRRQQNGQICVVESPADIHAIEQTGQFAGRYFVLMGHLSPLDGIGPDDIGLGRLEERLQVESISEVILATNPTVEGDATANYIAELCAQHGVMASRIAHGVPVGGELEMVDGTTLSHSLAGRQPFRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: IF5A3_SOLLC
Sequence: MSDEEHQFESKADAGASKTYPQQAGTIRKNGYIVIKGRPCKVVEVSTSKTGKHGHAKCHFVAIDIFTGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTDNGNTKDDLRLPTDENLLSLIKDGFAEGKDLVVSVMSAMGEEQINALKDIGPK
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-3, eIF-5A-3.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: HFQ_SALPC
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HISX_XANOM
Sequence: MKILDWSQLDVAARTDALTRPVQTVAAQTRNAVAALIADVRTRGDAALREITARFDGVSLERFAVSEAEFAAAEAAVAPELRQAMQDAVARIDTFHRAGMSEGYAVETAPGVVCEKIVRPIGRVGLYVPAGSAPLPSTALMLGVPARLAGCRAVVLCTPPRKDGSVDPAVLVAAWLTGVRRVFKLGGAQAIAAMAYGTESVPSCDKLFGPGNSYVTEAKQQVAQSGAAAIDMPAGPSEVLVIADAGAQAAFVAADLLSQAEHGADSQVLLLSDSDVLIDAVQAQLEIQLAHLSRADIARQALAQSRLIKVQTLDEAFAISNRYAPEHLILALREPRAWLAQVEAAGSVFLGDYTPEALGDYCSGTNHVLPTSGAARAYSGVSVASFQNMFSVQAASKAGIAGIGECALILARAEGLDAHANAVALRMGVAA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TORA_SHEON
Sequence: MNRRDFLKGLASTSFVALGGSSVLAPLNALANTGLNENEWLTTGSHFGAFKIKRKNGMIAEVKAFDLDKYPTDMINGIRGMVYNPSRVRYPMVRLDFLLKGHKSNTQQRGDFRFVRVTWDKALKLFKHSLDEVQTKYGPSGLHAGQTGWRATGQLHSSTSHMQRAVGMHGNFVKKIGDYSTGAGQTILPYVLGSTEVYAQGTSWPLILENSNTIVLWSNDPYKNLQVGWNAETHEAFAYLAQLKEKVKQGKIRVISIDPVVTKTQAYLGCEQLYVNPQTDVTLMLAIAHEMITQKLHDEKFIQGYSLGFEEFVPYVMGTKDGIAKTPEWAAPICGVEPHIIRDLAKTLVKGRTQIMMGWCIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSSIGVPATTAAAPGAFPRNLDENQKPLFDSTDFKGASSTIPVARWIDAILEPGKTIDANGSKVVYPDIKMMIFSGNNPWNHHQDRNRMKQAFQKLECVVSIDVNWTATCRFSDIVLPACTTYERNDIDVYGAYANRGILAMQKMVEPLFESLSDFEIFTRFAALLGKEKEYTRNMSEMEWIETLYNECKAANAGKYEMPDFATFWKQGYVHFGEGELWTRHADFRNDPEINPLGTPSGLIEIFSRKIEQFGYDDCQGHPMWMEKAERSHGGPGSNKYPMWLQSCHPDHRLHSQMCESKEYRETYTVNGREPVYISPEDAKTRGIKDGDIVRVFNDRGQLLAGAVVSDRFPKGVVRIHEGAWYGPVGKDGSVEGGAEIGALCSYGDPNTLTLDIGTSKLAQACSAYTCLVEFEKYQGKAPKVSSFDGPIEVEI
What is the function of this protein?
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
What are the official names of this protein?
Trimethylamine-N-oxide reductase, TMAO reductase, Trimethylamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UD18_HUMAN
Sequence: MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
What is the function of this protein?
Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A8, UGT1A8, UDP-glucuronosyltransferase 1-8, UDPGT 1-8, UGT1*8, UGT1-08, UGT1.8, UDP-glucuronosyltransferase 1-H, UGT-1H, UGT1H.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: JIP_CAEEL
Sequence: MACNLSPVNEMADSITSSTPSEIVYGGPGSPDEHRTMSDKVQTMASAIYRELETMIKVHGEDGVKTLMPLVVNVLEALDLAYLERDEQTAELEMLKEDNEQLQTQYEREKALRKQTEQKYIEIEDTLIGQNKELDKKIESLESIMRMLELKAKNATDHASRLEEREVEQKLEFDRLHERYNTLLRTHVDHMERTKYLMGSEKFELMQNMPLPNMQLRNKMGMAASVDASSIRGVSDLISAHMTQSTTMDVNLANHITNEDWQDEFSSDIEPSPRDIPQSSADALTSPITTKEPTPKREAASPKQSEEEEADETTSVDPKENNDLLGADLTDDESDWNGLGLIPRRHRPNEMLDDDDTSDDGSLGMGREVENLIKENSELLDMKNALNIVKNDLINQVDELNSENMILRDENLSRQMVSEKMQEQITKHEEEIKTLKQKLMEKENEQEEDDVPMAMRKRFTRSEMQRVLMDRNAYKEKLMELEESIKWTEMQRAKKMQQQQQNVNQKKSGGIWEFFSSLLGDSVTPPASSRGNRASSSRGKMTRSVEYIDPDMISERRAAERREQYKLVREHVKKEDGRIEAYGWSLPNVEAEVSSVPIPVCCRPLLDNEPSLKIWCATGVVLRGGRDERGQWIVGDPIYFAPASMKKTKTSNHRPELEDEIKRARNLDARESELDEWQSSSLVWVVSSNQGKSLIAVLDANNPNNIIETFPACDSHLLCIQAVSGVMEGEPEMNEEQSKKYLSGGGKIKDLPEGLDGTDLGACEWVELRKMEDSEDGVPTYCSNDMKPSPKRTRDFSISEVAPVDSSAPVKEDPLPPPANRPGGRAALPPHIRDAMSKYDGVSGQMSGALPTVWMGGQNQYIYIHSAVTAWKQCLRRIKMPDAVLSIVHYKSRIFAALANGTIAIFHRNKHGEWSDEGYHSLRVGSATSSVRSLCLVSTNIWATYKNCVVVLDAESLQIVKVFAAHPRKDSQVRNMQWVGAGVWLSIRLDSTLRLYHAHTYEHLQDVDIEPYVTKMLGTSKLDFSYMRTTALLVSNRRLWIGTGTGVIISVPFSGQLEKKIETKDSKRPAGPGGLVRVYGATSENATNDEKTNDDFIPYCNLAHAQLSFHGHKDSVKFFLGVPGASKNGEDESAEVTLRRMLIMSGGDGYIDFRIGEENEPELTGQSIRPRDMSHLIIWEVDAELPILSK
What is the function of this protein?
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module.  May function as a regulator of synaptic vesicle transport, through interactions with the JNK-signaling components and motor proteins.  Binds specific components of the JNK signaling pathway namely jnk-1, jkk-1 and sek-1.  Associates with components of the motor protein, kinesin-1.  Pre-assembled unc-16 scaffolding complexes are then transported as a cargo of kinesin, to the required subcellular location.  Regulates the retrograde transport of autophagosomes from the neurites to the cell body of AIY interneurons (PubMed:30880001).
What are the official names of this protein?
JNK-interacting protein, JIP, JNK MAP kinase scaffold protein, Uncoordinated protein 16.
What is the protein family that this protein belongs to?
Belongs to the JIP scaffold family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Diffusely localized throughout cell body but intensely localized in regions adjacent to nucleus and at presumptive tips of neural processes.
Protein: NANE_ECO45
Sequence: MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: YCEH_ECO81
Sequence: MKYQLTVMEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVENPPAVTDMSNAADGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: UREF_STRE5
Sequence: MNINPFANVSLQDYLEIVQIVDSTFPIGSFNHSFGMENYLREDTVTDDKGYEEWQEAYLASQFKYGEGLVIKLVYDAMATDNLEQVWHYDKVLTVSTQARETRQGTKMIAKQMLRLIQRLHAIPVLDDYQSKIRKGEVFGNPAIVFALYVFNKGLGCSEAIALYGYSVISTMVQNAVRAIPLGQFAGQEIVLRSFSQLEKMTQEIQELDASYLGANTPGLELAQMKHETQVFRLFMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BLAGS
Sequence: MVTIVLGAQFGDEGKGKITDLLSQSATLCCRAAGGHNAGHTIVHDNITYDFHILPSGLISPDCVNLIGSGTVVHVPSFFKELDALKAKGLKEADKRIFISDRAHVCFDLHSVVDGLEEADLAGKKVGTTGKGIGPCYSDKASRRGVRIGEVLEEGVAEDKLRSLEAGYRRRFGELQYDLEDEVKRFNEYRTKLQPYVVDQMAFLEKYRSCPSVLVEGANALMLDIDHGTYPYVTSSCTGLGGAIQGLTLNPTSIKSIVGVVKAYTTRVGSGPFPTEQINDIGEKLQSVGREFGVTTGRRRRCGWLDMVMCRYSNAINHYTTINLTKLDILDDFDEIKVAVAYKLDGRRLESFPAQLEVLDKVEVEYVTFPGWKSNTMGVTRWEDLPVNARRYVQFIEQEMGGVPIKWIGTGPARTHMIEREV
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_HYDS0
Sequence: MIETIASKLLVQNVSQYFILSFILLGIGLFGMMVRKNLITILMSLELALNSVNIAFVGIDRLNHLIDGEIFALFTIALAAAEAAVGLGIILSLFRLRKAENVNEIIDLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RTCA_DICDI
Sequence: MGKNKNYNKNQFKKSKTNNDTTVAQQQQTIEEKPDFKIDGSILEGGGQILRNSVALASLFNKAISIEKIRYNRDQPGLKNQHKAGIDLMSRLFKAHLTGCSVGSCKLYYQPTQKTIQDDGVIEADTKTAGSICLMIQVSLPCLIFAPHSTKMVLGGGTNCDFAPAADYIQNVFLPIATTMGFKCEMSIDKRGFYPKGGGAVTLTTQPLTQPLSPITIVNKGEVNRIVIKSYFTSPRISPLVAERMNNTAKKLIKKDFKKVDVETELIDVSKFSFGDGTFIEIRAYTDQGCIFGATGNGAIGVPAEKVAEDAANSLLKDLQDGGCMDEYLQDQLIIFMALAKGKSQIKTGPISLHTQTSIHITSLMTGAIFTITPLTNNTQSGEETNLITCEGISYFPSDLNNNNNNSNSNTTTTTTTTTISTTTIDNQNSEEK
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
Probable RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: CRCB2_LACDA
Sequence: MIFAVGFGASLGAVARYALTSYGKKHWMQGTACPRPTLLINLTGAFFLGLAFALRLPASVYAFLGTGVLGGYTTFSTLNTEMVSLAENGQKHVLKHYLLASYLGGAVLLTCGYYLGSLL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEPT_LACHE
Sequence: MEYPNLLPRFLKYVKVNSRSDENSDRFPSTEREENFQKNVIMKDLEELGLSDIHYNQKAGSVIAEIPSNVDYDVPVMGFLAHSDTADFNSENVKPQIHKNYDGESKIQLGDSEFYLDPEVYPNLRKYKGQTIITASGDTLLGADDKCGISELMTFAEYLMNHPEVKHGKIRLAFTPDEEIGTGAEQFDVKDFGADFAFTVDGEAPGKLGDCTFSAAQFTLDIQGVNVHPAVAKGQMINAVQVGIDFHNQLPEHDRPEHTDGREGFFHLLSFDGTVDHAHLAYIIRDFERDGLEERKNLVKSIVKKMNDEFGTERIKLQMNDQYYNMADELKKHMDIVDLARDAYKAEGLEVNEDPVRGGTDGSQLTYMGLPCPNIFAGEENMHGRYEYTVLESMYKTVDVMIKMAELNAERAK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.  Shows broad substrate specificity, exhibiting maximum activity against hydrophobic tripeptides, with the highest activity for Met-Gly-Gly.  Therefore this enzyme may play an important role in flavor formation during cheese ripening.  Is also able to slowly hydrolyze some hydrophobic dipeptides, but displays no activity against tetrapeptides and the tripeptide Phe-Gly-Gly.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_ECO55
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBCR_CYAM1
Sequence: MTDLPFTLDQLRIFQAIVVEGSFQKAAQSLYISQPAVSLQIQNLEQQLNAPLFDRSHRKAKLTEAGQVFFKYASRILALCEETCRALEDLHHLQAGSLIIGASQTIGTYLMPGLIGLFRQKYPHICVQLQVHSTRRIAWSVAKGHIDVAVIGGAIPTELIPLLSIQPFAEDELTLIVPPDHPFARLSKIQKEDLYRLRFVSLDRHSTIRKVIDQILHQNGIDTNRLKMEMELNSIEAIKNAVQWGLGAAFVSVCAIAKELELNLVREVEIEAISIKRQLYQITNPNRYQSKAAFTFCQQMLNV
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: WN10A_PLEJO
Sequence: SGSCQLKTCWQVTPEFRVVGNLLKERFYGATLIKPHNRNTGQLDHSHIPHRRRTSINSLVYFEKSPDFCEREPQLDSTGTQGRICNKTSPGMDNCESLCCGRGHNILRQTPSERCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Required for normal tooth development.  Regulates the expression of genes involved in tooth development.
What are the official names of this protein?
Protein Wnt-10a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: DCD_SALPK
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RBSA_BACCZ
Sequence: MRIEMKNISKAFNGNPVLKNAQFMIETGEVHALMGENGAGKSTLMKILTGVYKRDGGTITIDGQERTFKNAKEAEEYGIAFIHQELNILPNLTVAENMFLGKELMYGKTGILRTRQMNAIAQQQLAELGLHVKGAMLAGELSVGQQQIIEIAKALMTNASVIIMDEPTAALTDREIETLFTVINKLRKEGVSFVYISHRMEEIFSICDAITILRDGEYVGKRSIPETSFDEVVSMMVGRSIGERYPERNSQISDVIFEMRNGTKKGKFENVSFQVRKGEILGVAGLMGAGRTDIMKSIFGYEPLDSGQIFINGQEVKIDSPIDAIRQRIAFITEDRKSEGLVLDFSIRENLALPNLESLSKGSVLSNELEQQFTADMMKLLNVKASSGEQAVKSLSGGNQQKVVIAKWLGIHPQLLILDEPTRGVDVGAKKEIYSIMNKLTEEGDAVIMVSSELPEVLGMSDRVLVIHEGKVGGILEKDEASQESIMALATGGE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ADH2_GEOTN
Sequence: MQNFTFRNPTKLIFGRGQIEQLKEEVPKYGKKVLLVYGGGSIKRNGLYDEVMSLLTDIGAEVVELPGVEPNPRLSTVKKGVDICRREGIEFLLAVGGGSVIDCTKAIAAGAKFDGDPWEFITKKATVTEALPFGTVLTLAATGSEMNAGSVITNWETKEKYGWGSPVTFPQFSILDPTYTMTVPKDHTVYGIVDMMSHVFEQYFHHTPNTPLQDRMCEAVLKTVIEAAPKLVDDLENYELRETIMYSGTIALNGFLQMGVRGDWATHDIEHAVSAVYDIPHAGGLAILFPNWMKHVLDENVSRFAQLAVRVFDVDPTGKTERDVALEGIERLRAFWSSLGAPSRLADYGIGEENLELMADKAMAFGEFGRFKTLNRDDVLAILRASL
What is the function of this protein?
Long-chain alkyl alcohol dehydrogenase that can oxidize a broad range of alkyl alcohols from methanol to 1-triacontanol (C1 to C30) as well as 1,3-propanediol and acetaldehyde.  Oxidizes isopropyl alcohol, isoamylol, acetone, octanal and decanal.  The best substrate is 1-octanol.
What are the official names of this protein?
Long-chain-alcohol dehydrogenase 2, Alcohol dehydrogenase 2, ADH2, Fatty alcohol oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: UVRC_LEPBL
Sequence: MPEILNHILILEKIKNLGISPGCYLWKSRKGEVLYIGKAKNLDKRVRNYLKENHPDIKTRALQKEIFDLDWIATGTEKEALILEATLIKKHNPRFNVRFKDDKKYPYICVSLSESFPMVYITRKLKDNGDRYFGPYSDVKSTRETLDIILRIFPVRKTRQVLPLPKPRRPCLNFDMGRCLGPCQGNIPVEDYKIVIDQVIQFLEGKKESLVGDLSIKMSASSNRMDFEKAARYRDMLQRIQNFREKQTVVSAEGGDEDVIGFARKKDEGQVILLEVRGGRLETKKSFPIQGVLDAEDSEILGAFFRDYYLNAALVPPLIFVPADIQEETAAVMDVLQEKTGFRPKLKSPRGGDKRSLLKIAEKNAELGLTERLLATHYRDQTASLKEIQEMFSLEHPPHIIECYDISHFQGSEPVASGVMFVEGKPFKQGYRKYNIRGYKGINDPGMIHEVISRRLQRIANEESVFPDLIVIDGGPTQLAKACEAAMEAGAERIPMIGLAKKREEIYFPGDNEPFIFDMNSSGMKLLRHLRDEAHRFGVSHHRSRRNKETMRSLIQNVPDIGLKRSKLLLRHFSGEKKIEDATKEELLAVPGIGENLAEKILKRIRKKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y138_METJA
Sequence: MEIGILDIKGSLPLFEDFGNLPTKIITENNYKEIKDLDALIIPGGSLIESKSLNDDLKKEIINFNGYIIGICSGFQILAKKIDIGRKSSVPIIKEGLGLLDVEFSPLVCTDRVEFEVKKSIFGEGKGEGFHCHTYGNIEVVDKETKILTVSKVKKLNYKLGAEKEIISGAFKGKVFGTMVHNFLDNEFVRDNFLKHLGVTEDEKEEIFEKNKIIKDELKKRALKYRLNPKLLKENNKKDVNKKRGIILLATSSNSGKTFLTTALSSKLNGRVFVAKIGGDVRDIVPALYLLREKMTKYNSIKIGERGWVDVSKFLDYIKKSDYDYIIVEGVMGAFTAALKNISSYQIAKKLGFPVYIVSACNISGIEGAFVEAMAYYSLLKDIGIKVEGVILNKVYDWNSFNKLKSLAEKHNIKLYGVGKIANESRGLIPEVEIDYESFCRNAFNVDLEIEIPEVEINNHIKDEEDNFLERLDNWMENINKY
What are the official names of this protein?
Putative glutamine amidotransferase-like protein MJ0138.
Protein: IMDH_STRP1
Sequence: MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.