PharMolix/UniProtQA huggingface dataset:
Protein: GONS3_ARATH
Sequence: MSTNDEENGTVIEVKNVPEPSPETWYSVFLRQASVYGVAAGYCLSASLLSIINKWAIMKFPYPGALTAMQYFTSAAGVLLCAQMKLIEHDSLNLLTMWRFLPAAMIFYLSLFTNSELLLHANVDTFIVFRSAVPIFVAIGETLFLHQPWPSVKTWGSLATIFGGSLLYVFTDYQFTIAAYSWALAYLVSMTIDFVYIKHVVMTIGLNTWGLVLYNNLEALLLFPLELLIMGELKKIKHEITDETDWYSLQVVLPVGLSCLFGLAISFFGFSCRRAISATGFTVLGIVNKLLTVVINLMVWDKHSTFVGTLGLLVCMFGGVMYQQSTIKKPNATQEAKPQEQDEEQEKLLEMQENKESNSVDIKETLKSEEKL
What is the function of this protein?
GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter GONST3, Protein GOLGI NUCLEOTIDE SUGAR TRANSPORTER 3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. GDP-Mannose:GMP antiporter (GMA) (TC 2.A.7.13) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: PSAI_ANTAG
Sequence: MTASYLPSILVPLVGLVFPAITLASLFIYIEQDEIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ART10_YEAS6
Sequence: MAPKISISLNPPYNGEFYSSNDQMSGIVSLQLTKALSIRKISVILKGFSETLTKIDQEYMFQQNGMMMPGQDNKSFHTLMKFEQRVFPPDNVWNALDGSSKPFKVKPGSYNYSFQFDKFPRKPECLKNHTAKTVAFVTRNNARLPPTFNSHWQEFNKIDNLDLYFYSFGKVIYMVQVQIELGKSSSWFKPFHKLIREIETFEFIPEPKDLIVEPDEDDNEELNAFSNNSRGNSLVTNNEFFNSSNLKVPSKDVKVVNGVGYIKSDRNFSQANSILIENGDIRSRPVSSVTSTRQSTRLVNGMKVFPSTYKMGLPDGESNMRIEVRSRDLKQIYRKDYLFRSGSQNFDKVYVVMEGNIASLSKMQITPLKLQLNLLETTTYLSQGIANGNYSSLKLIEIDLNQLKSNKPLLDLNEIRENFDGSMFECELRLKDHPILRKLVFNEEDYRHRGNRLYSFKTCTIKRIFSLQLLIEWGINGIRKQSEVNIDPVQIFCQVREHVEAEALPRYVPPPTYTEMAS
What is the function of this protein?
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
What are the official names of this protein?
Arrestin-related trafficking adapter 10.
What is the protein family that this protein belongs to?
Belongs to the ART10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPE17_CAEEL
Sequence: MQMADIAKQREQPPRAMSTTSGSDVLKSTTTGTTTGTTKSSVHTSDTNYGVGSLRSDCSEEGFGSNLTPEEANWLNMARVFTKAEKPFKEQKTFRVARKLRTWRPRRSVTWSFLRRLYNGREDMKEDLIRDLADLEIEDKPV
What are the official names of this protein?
Spermatogenesis-defective protein spe-17.
Protein: SPN90_MOUSE
Sequence: MYRALYAFRSAEPNAMAFAAGETFLVLERSSTHWWLAARARSGETGYVPPAYLHRLQGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGTSASSATVMTPSTSDHHLDAAVSRQPNGVCRTGFERQHSLPSSEHLGTDGALYQVPPQPRRAAPTTPPPPVKRRDREALVISGSGGRTAIPSGGSSVSSGSSASSTSMDTLYTGSSPSELGPSCSPTPPPVPRRGAHTTVSQPQPSPSKAPSPEPPTEEVAAETNSTPDDLEAQDALSPETTEEKAAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQATVPASSPIMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPMDTTEQLPDLCMNLLLALNLHLTAPEQNVIMAALSRHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSSATAAIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEEASPQCQMDRMIVQEMYKEFPDLGEVPS
What is the function of this protein?
Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1) (By similarity).  Induces microspike formation, in vivo.  In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42.  May play an important role in the maintenance of sarcomere and/or in the assembly of myofibrils into sarcomeres.  Implicated in regulation of actin polymerization and cell adhesion.
What are the official names of this protein?
NCK-interacting protein with SH3 domain, 54 kDa VacA-interacting protein, VIP54, 90 kDa N-WASP-interacting protein, 90 kDa SH3 protein interacting with Nck, SH3 adapter protein SPIN90, WASP-interacting SH3-domain protein, WISH, Wiskott-Aldrich syndrome protein-binding protein, N-WASP-binding protein.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
Protein: ARLY_ARATH
Sequence: MGAIDLSFSQSLLFSSSRSNLSSSTHRSVSFLPPGSKSRCLPPLRSMSHDDDTASKEVKLWGGRFEESVTEKVEKFTESISFDKVLYKQDIMGSKAHASMLAHQGLITDSDKDSILRGLDDIERQIEANKFEWRTDREDVHMNIEAALTDLIGEPAKKLHTARSRNDQVATDFRLWCRDAIDTIIVKIRNLQRALVELALKNEALIVPGYTHLQRAQPVLLPHVLLTFVEQLERDAGRYVDCRARLNFSPLGACALAGTGLPIDRFMTANALGFTEPMRNSIDAVSDRDFVLEFLYTNANTGIHLSRLGEEWVLWASEEFGFMTPSDSVSTGSSIMPQKKNPDPMELVRGKSARVIGDLVTVLTLCKGLPLAYNRDFQEDKEPMFDSTKTIMGMIDVSAEFAQNVTFNEDRIKKSLPAGHLDATTLADYLVKKGMPFRSSHDIVGKLVGVCVSKGCELQNLSLEEMKKLSPVFEEDVFGFLGVENSVNKFSSYGSTGSNCVAEQLGYWVNKLNITST
What are the official names of this protein?
Argininosuccinate lyase, chloroplastic, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPG1_YEAS7
Sequence: MKLDSGIYSEAQRVVRTPKFRYIMLGLVGAAVVPTAYMRRGYTVPAHSLDNINGVDTTKASVMGTEQRAAMTKGKSLQEMMDDDEVTYLMFSSIM
What are the official names of this protein?
Stationary phase gene 1 protein.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: TRML_AERHH
Sequence: MLDIVLYQPEIPPNTGNIIRLCANTGYRLHLIEPLGFEWDDKRVKRAGLDYHEFAEVKRWPNFEAFLEAVAPTRVFACTTKGRTAHSAVQFAAGDALLFGPESRGLPIEIIESLPFEQRLRIPMLPQSRSMNLANAVAVFVYESWRQLGYAGSLQE
What is the function of this protein?
Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA).  Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
What are the official names of this protein?
tRNA (cytidine(34)-2'-O)-methyltransferase, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_MICAN
Sequence: MVAIRPDEISTIIRQQIESYNQEVQVSNVGTVLQVGDGTARIYGLQQAMSGELLEFEDGTVGIALNLEEDNVGAVLMGDGFGIKEGGTVKATGKIAQVPVGDALVGRVVDALGRPIDGKGEILASETRLVESPAPGIVARKSVCEPMQTGITAIDAMIPVGRGQRELIIGDRKTGKTAIAIDTIINQKSEDVICVYVAIGQKASTVAQVIDTLTQRGAMDYTVVVAANANDPATLQYIAPYTGASIAEYFMYKGKATLVIYDDLTKQAQAYRQLSLLMRRPPGREAYPGDVFYLHSRLLERAAKLSDALGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSTDLFNAGFRPAINAGISVSRVGSAAQTKAMKKVAGKLKLELAQFDELEAFAQFASDLDAATQAQLARGQRLRQILKQPQNFPLSVWEQVAVVYAGLNGYLDDIATDKVIDFCAGLREYLKTSKPRYVEIVSTEKQLNDEAEGLLKDGINEYKQAFK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: KLH12_HUMAN
Sequence: MGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTMEILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNCLGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKCDEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDVIDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIGGYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport (PubMed:22358839, PubMed:27565346).  The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B) (PubMed:22358839, PubMed:27565346).  The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts with the heterodimer formed with PEF1 and PDCD6/ALG-2, leading to bridge together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export (PubMed:27716508).  As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3 (PubMed:16547521).  The BCR(KLHL12) complex also mediates polyubiquitination of DRD4 and PEF1, without leading to degradation of these proteins (PubMed:18303015, PubMed:20100572, PubMed:27716508).
What are the official names of this protein?
Kelch-like protein 12, CUL3-interacting protein 1, DKIR homolog, hDKIR.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle.
Protein: GSA_VEREI
Sequence: MTPNTDLNIPLFERAKALIPGGVNSPVRAFKAVGGTPRFVKRARGAYFWDANDQRFIDYIGSWGPMILGHGHPAVLEAVQQAALEGLSFGAPTERELELAEAILRLLPSMQMIRLVSSGTEAGMSAIRLARGATGRSKLIKFEGCYHGHADALLVKAGSGLATFGNATSAGVPAEVVQHTLVLEYNSIEQLERAFALHGKELACLIIEPIAGNMNLVRASVPFMRRCRELCSEYGALLVLDEVMTGFRVAPGGAQSLYARDIPGFQPDLTVLGKVIGGGMPLAAFGGSRALMEHLAPLGAVYQAGTLSGNPVATACGLATLRAIGQPGFFAALSARTRALVEGLRGAAAAEGVAFSADSEGGMFGFFLLPALPRNYAQVLQTDSARFNQLFHGLLERGIYIAPALYEAGFVSAAHSDEDIAATVAAAREVFKTLAKP
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_URORI
Sequence: MTNIRKTHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLILALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHLSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFTIILLILPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y5645_HAEIE
Sequence: MKLQGAGLGYRRNLAEDFLQLPPNNAIQFIEVAPENWSKMGGMARYQFDQAAERFPLAVHGLSLSLGGQAPLDRKLLRNTKALMNQYNSSFFSEHLSYCECEGHLYDLLPMPFTEEAVKHVAQRIRDVQDFLGLQISLENTSYYLHSPTSTMNEVEFLNAIAQEANCGIHLDVNNIYVNGVNHGLLDPYVFLDQVDVKRVNYIHIAGHDEEHSAAQVVENSADESFNKVKGAYRHLPELLIDTHGEAVKGTVWDLLEYAYQRLPTIPPTLLERDFNFPPFAELYAEVEHIAQLQQKYAHTEVMSYAA
What are the official names of this protein?
UPF0276 protein CGSHiEE_05645.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: TEX12_MOUSE
Sequence: MMANHLVKPDSRNCKRARELEPQVSDSPQVSSLGKSESSLSEASGLFYKEEALEKDLSDMSKEINLMLSTYAKILSERAAVDASYIDEIDGLFKEANIIENFLVQKREFLKQRFTVITNTLHK
What is the function of this protein?
Component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:16968740).  Requires SYCP1 in order to be incorporated into the central element (PubMed:16968740).
What are the official names of this protein?
Testis-expressed protein 12.
What are the subcellular locations of this protein?
Chromosome. Note=In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed.
Protein: FLAB1_AERPE
Sequence: MRRRRGIVGIEAAIVLIAFVIVAAALAFVALNMGLFTTQKSKEVMQRGLEEATSALEVDGSVIANVTSGSVDAIAIPIKVSPGREGVDMSVDKTTVRVMLPSKFYENAYCGVFDGSSLSDSKLSTITSSIACTTGWAYLVIFNGDGDNVLELGEKGLLVLELPTPLNSYEEFKVEVRPVQGAALTVERIVPASLPTGGAVSLG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Probable flagellin 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: RS16_BURP6
Sequence: MVIIRLARGGSKKRPFYNIVATDSRNRRDGRFIERVGFYNPVATKGEALRIAQDRLTYWQGVGAQLSPTVERLVKQAQKAQPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL30_DICDI
Sequence: MVSVKKVKKSQENIGSKLALVMKSGKSQLGYKSTLKTLRAGKSKLILLASNLPSIRRSEIEYYAMLSKTTVHLYSGNNVDLGTALGRHYRVSVMSITDAGDSDILTALNAKA
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: TILS_BIFLD
Sequence: MAYSARLRKAVGAVRTTLSAVELCDVQAPEFAQHGDHAVASDAPLVLVACSGGRDSMALAAVSHIVCTSMGVRCGVVIVDHGLQEGSEQVAGEAANRCRALGLGPVIVRNATVQARGEGLEAAARQARYNELCAAARESGAIAVLLAHTMDDQAETVLIGLLRSRGVDALAGMPQVFTRSGVTFARPLLTLTRAETTGICEDLGVEYWDDPTNGDAVDGELPNDYPLRSRVRHDLLPAIERFAGFNVTRHFAESARLARMDKEYLDQRSDEVMGEAVTTVDWPASSAAVSTDTPRACAAGDTNDSSHGVGLMISVRRIAREPEAIRLRVIAHALSQAGVNASAAQIAAIDRLVVDWHGQGGVSLPRGYSANRKKHVIRVCQDGAHANR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APD2_ARATH
Sequence: MSLPDSLPSSSSSPPVTREETGFHRFEHHGNDSGFDHRDRPPWNRSEYDYRHGSVVASENVRNNSTSEDPWSCVVVVATFCIFVSMTLILGLYGTTNVWLGPNSSFLIKPTSVFVQNVIVEELGNKGSGLILYGLNQAPQLDVLTKWSEVHYLAVPNDSYKYWIQYLNKGSRVKVSYNVESVGSSLYLVIAQGVDGLSEWVQDPTRPDTTLSWHIISDSGYIEQDITKSSSYYVAVGNVYLNEVKATIDIQVEGVLYDTTNAYYNCSFPNDKCTLSVPLFGTNAAVLTSPGPKLNNSKNEFCAKLSYEPRWIAYIVCMGVVTALLLIVSSLFNKRQPVTEDETVDENDDVAPLIPGKDDDNSSWCSSYSSILTSTEELEGAHGEGHSSTRYLCAICYDAPRDCFFLSCGHCVACFQCGTRIAETSGFCPVCRKKIRKVKKIFNV
What is the function of this protein?
Exhibits E2-dependent E3 ligase activity (PubMed:22897245).  Involved in pollen mitosis II (PMII) regulation during male gametogenesis (PubMed:22897245).
What are the official names of this protein?
E3 ubiquitin-protein ligase APD2, Protein ABERRANT POLLEN DEVELOPMENT 2.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Note=Associated with intracellular membranes and in the tonoplast and endosomes in the germinating pollen tubes.
Protein: NIPS2_HUMAN
Sequence: MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
What is the function of this protein?
May act as a positive regulator of L-type calcium channels.
What are the official names of this protein?
Protein NipSnap homolog 2, NipSnap2, Glioblastoma-amplified sequence.
What is the protein family that this protein belongs to?
Belongs to the NipSnap family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane.
Protein: CFI_CAMSI
Sequence: MSPSQSPSVAQVQIESHVFPPTVKPPGTSKPFFLGGAGERGLEIQGKFIKFTAIGVYLEDSAIPSLAVKWKGKTAEELTDSVDFFRDIVSGPFEKFTQVTMILPLTGQQYSEKVTENCVAYWKAVGTYTDAEAKAIEKFIEVFKDETFPPGGSILFTQSPLGSLTIAFSKDGSLPETGTVVMENKQLSEAVLESIIGKHGVSPAAKKSLAARMSELLKEKPEAQTAAAAE
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: APT1_ARATH
Sequence: MQTIIISPLVSHRLCLARAVPCNRLLNNHHRAPPSIRLSNHRSTTSLRLFSSAAASRDSEMATEDVQDPRIAKIASSIRVIPDFPKPGIMFQDITTLLLDTEAFKDTIALFVDRYKDKGISVVAGVEARGFIFGPPIALAIGAKFVPMRKPKKLPGKVISEEYSLEYGTDTIEMHVGAVEPGERAIIIDDLIATGGTLAAAIRLLERVGVKIVECACVIELPELKGKEKLGETSLFVLVKSAA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.  Contributes primarily to the recycling of adenine into adenylate nucleotides, but is also involved in the inactivation of cytokinins by phosphoribosylation.  Catalyzes the conversion of cytokinins from free bases (active form) to the corresponding nucleotides (inactive form).
What are the official names of this protein?
Adenine phosphoribosyltransferase 1, chloroplastic, APRT 1, AtAPT1.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
[Isoform 1]: Plastid, chloroplast. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: PSMG1_DANRE
Sequence: MATFFGEVLSVYSRAVEEDEYEDMTNENEEDEQIRREIEEKRSVEVCWLLGSQDGPLQCSDLIIGAGPNASGFIRAYLLSTVGWTAVAWLSFWNERSRGSERPTVVPGPGEPSCVLYRLESCPTVLICQCQGFVAEDQLFQFTEKVFSCVQTRDLNVTILSDCSSADYKTSDYLSGSSTPFLRCLKTSTYTHTVTCPPLEQPNICSGLAAAVLSHCQVHQISAVLYQCYSDVLHPDSASMQMFAATLSSVLKLEQSLSADVLQRVTRVSEIQSNLYT
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
What are the official names of this protein?
Proteasome assembly chaperone 1.
What is the protein family that this protein belongs to?
Belongs to the PSMG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: TCEA1_MOUSE
Sequence: MEDEVVRIAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNALRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDPEEKKKEPAISSQNSPEAREESSSSSNVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
What is the function of this protein?
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
What are the official names of this protein?
Transcription elongation factor A protein 1, Transcription elongation factor S-II protein 1, Transcription elongation factor TFIIS.o.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTG1_AVIVO
Sequence: MKKNIMGLSLFSSAGIGEYFLSRVGIDIIVANELIKKRADLYQKIYPNHKMVIGDIRDQRIFNKVLNIALTNQVDFLIASPPCQGMSVAGKNRDVSNMANDNRNYLIMYVIAMIKKLKPAYILIENVPFLLKLELYIDNKLTPIKNILEDEFGSEYHIHFDILDAADYGTPQRRKRAIIRLNKKGTIWNLPLKQNIVSVEQAIGNLPSIESGKHSGLKWHYGRGHTEQQIEWMKHTPTGKSAFENLVHYPRKANGEKVKGYHSSYRRIRWDEPAPTITIRNDAISSQRNVHPGRPLLDGTYSDARVLSVLELMRLTGLPDNWEIPDDTPEILIRQIIGECIPPLLIENITREIFNEN
What is the function of this protein?
A methylase that recognizes DNA with the sequence 5'-GCGTC-3', methylates C-2, and protects the DNA from cleavage by the HgaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M1.HgaI, M1.HgaI, Cytosine-specific methyltransferase HgaIA, M.HgaI-1, Modification methylase HgaIA, M.HgaIA.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: ENDA_SULIM
Sequence: MVKALLVGSKVLIPNVDESRYIYSTGFYGKAIGISKPKGPKDIIRPLELSLIESVYLAKKGLIKVIDKNGEVLEYEKLYEYSSKIINKFDIMYRVYEDLREKGFIVRSGVKYGADFAVYTLGPGLEHAPYVVIAVDIDEEITPHELLSFGRVSHSTRKRLVLALVDRKSESVRYIMFKWVKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: GCSH_CLOBM
Sequence: MKVLNNLLYTGDHEWIRVEDNKAYIGISDCAQRMLSDIVFVELPEVDDEIAKGETFATIESVKAASDSYMPVSGTIVEINEELEDNPAALNEDPYGSWIIAVEMSDKSELEELIKPEVYEKICEELDKEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NUSG_STAAM
Sequence: MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTVLVDMFGRETPVEVEFDQIEKL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RL30_METB6
Sequence: MYAVVQVRGVVNTRKDIKDTLKMLRLHHINHCVLVADTPENLGMIRKVKDYVAYGEVDAATLETILKTRGRVIGDDPLTDEYIKSNSSTYSSIVEFAQALAKGESRLRDIPGLKPVLRLHPPRKGYKTTKRTFVQGGALGYYGPEINTLLYKMR
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ISK6_BOVIN
Sequence: MKTSGVFLLLSLALFCFFSGVFGQGAQVDCAEFKDPKVYCTRESNPHCGSDGQTYGNKCAFCKAVMKSGGKINLKHRGKC
What is the function of this protein?
Serine protease inhibitor selective for kallikreins.  Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14.  Doesn't inhibit KLK8.  Inhibits acrosin, trypsin, and chymotrypsin.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 6, Acrosin inhibitor 2, Acrosin inhibitor IIA, BUSI-II.
What are the subcellular locations of this protein?
Secreted.