PharMolix/UniProtQA huggingface dataset:
Protein: LPXK_SHESW
Sequence: MQTLVNKIWYQGHPLQWLLLPLSFVFGFITFVRRGLFQLGLKAQTILPVPVIVVGNITVGGSGKTPMVIYLIELLRAHGFNPGVISRGYGANIDGVKQVAYNASATDVGDEPAMIVARSGVPMVVGSKRVEAANVLIAEHGVDVIICDDGLQHYALGRDIELVVIDGQRRLGNEYLLPAGPLREGPWRLKDVDFVVINGGNADVGQFEMQLAPTQVKAVDGNIITTDFDKSQPLVAMAGIGNPTRFFDSLQAQGYQVVLSHGFDDHQAYDKKQLCDLAKDLPLMMTEKDAVKCRDFAQENWWYLAVNAKLSPQFDEQLLSRLHEVVAAKQGNSHGIR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: AROA_RHILO
Sequence: MSHAAAAKPATARKSQALSGTARVPGDKSISHRSFMFGGLASGETRITGLLEGEDVMRTGAAMKAMGAHIEKRGAEWVIRGTGNGALLQPEGPLDFGNAGTGSRLTMGLVGTYDMETTFIGDASLSGRPMGRVLEPLRQMGVQVLKATPGDRMPITLHGPKHAAPITYRVPMASAQVKSAVLLAGLNTPGITTVIEPVMTRDHTEKMLKGFGANLSVETDERGVRHIFIEGQGRLTGQTIAVPGDPSSAGFPLVAALIVPGSDITIENVLMNPTRTGLLLTLQEMGGQIDILNPRNAGGEDVADLRVRYSELKGVAVPPERAPSMIDEYPVLAVAASFAEGETLMQGLEELRVKESDRLSAVANGLKLNGVDCTEGEASLAVRGRPGGKGLGGHPNGLDTTVQTHLDHRIAMSFLVMGLATEKPVTIDDQAMIATSFPEFMGLMTGLGAEIR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_SHESM
Sequence: MNEQLHNRTMAFAGILQAIAQVQHLARHGESDTDELAASLNTILVTNPESAADVYQDKAALHKGYQLVLNQLGDSSQKDVEITRYLVGILALERKLTRSNSGLAMLAERINQVNRQLHHFAITDEQVIANLASIYSDIISNLGPKIQISGNPLCLQRPIVQHKIRALLLAAMRSAVLWRQLGGKRRHLVFARKAIIDTAKKSLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLO2_NITHX
Sequence: MTADIRLFTCLTDNFGVLIHDPATDATAAIDAPEAGPIIEALDREGWTLTDILVTHHHADHIGGIAELKQKYKCRVVAPHDKKAPIANVDLRVGQGDIVKVGTLLGRVLETPGHTLDHISYVFDDEKVVFAADTLFSIGCGRVIEGTYPMMWDSLLKLRALPDDFRLYCGHEYTASNVKFALTVEPNNAALKARAEDVARLRAENKPTVPTLMGEEKKANVFLRADDPAVAAGVHMKGASGADVFGELRERKNKS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: IBPA_ECOHS
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_SYNEL
Sequence: MAKVLKKPDLTNPALRAKLKKGMGHNYYGEPAWPNDLLYIFPVVIMGTIALVIGLAVMDPAMVGEPADPFATPLEILPEWYLYPTFQIFRVVPNKLLGVLMNASIPLGLMLIPFIESVNKFQNPFRRPVAMTVFLFGTLVTLWLGIGAAFPLDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: AV2_TYCS2
Sequence: MWDPLLNEFPDSVHGLRCMLAIKYLQLVEETYEPNTLGHDLIRDLISVIRARDYAEANRRYTNVKPALEVSSKTELRQPVYQPCCCPHCPRHQASIMDLQAHVSKAADVQNVQKP
What is the function of this protein?
Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein V2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AV2/V2 family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity).
Protein: FIXN_AZOC5
Sequence: MSIVQTPAKRMTGGELGLILVFAALGFFSIVVAAKAYTPEYAFHAYLFAAASIATVFVIGNRYMDRPAELPPQTIDGKPNYNMAPVKVGTLLAVFWGIAGFLIGVIIALQMAYPLFNFDLPWISFGRLRPLHTSAVIFAFGGNVLIATSFYVVQRTSHARLAGYLAPWFVVLGYNFFIVIAGTGYLLGITQGKEYAEPEWYADLWLTIVWVTYFLVFLGTVLKRKEPHIYVANWFYLAFILTIAVLHLGNNAAIPVSVFSPKSYIVWSGVQDAMVQWWYGHNAVGFFLTAGFLALMYYFIPKRADKPVYSYRLSIVHFWALIFLYIWAGPHHLHYTALPDWAQTLGMTFSIMLWMPSWGGMINGLMTLSGAWDKLRTDPIIRMMVVAVAFYGMATFEGPMMSVKSVNSLSHYTEWGIGHVHSGALGWVAYISFGAIYCLIPWLWNKREMYSMKAIEWHFWVSTLGIVLYICAMWVAGILQGLMWRAYTALGFLEYSFIETVEAMHPLYVIRAIGGILFLAGSLIMAWNVFMTITRAETVSQPSGAALAPAE
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  Co I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B.
What are the official names of this protein?
Cytochrome c oxidase subunit 1 homolog, Cytochrome c oxidase polypeptide I homolog.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y739_METJA
Sequence: MISVKDVVNYNPEEYKFKSREIPSDLLAIIIYAYMQKVKDLGSDTTLYEIGYEVGRLVSPKSYEDIKKFFEANNIGYIEIKEKDNGEVEIKVKDCIFCRTQKSEEPMCDFEAGLIAGFLESIKNKKYFVKEMYCQAQGYDACVFIAKPLHN
What are the official names of this protein?
Uncharacterized protein MJ0739.
What is the protein family that this protein belongs to?
Belongs to the M.jannaschii MJ0150/MJ0739/MJ0745/MJ1460/MJ1642 family.
Protein: DEFI8_CAEEL
Sequence: MSSWCSSEDAHNQSSTPSTRSRKSSWLISKIDENEIDKEVQEMMDDWRRSNEAENHVECIKAALEYCRDKLKELLIDEEDTEMDGKETKTKPINIVSNTEFPEDRDVLGNLVNCLDRQQKAARQQMYFDKIVQLGLERQALQDEAVVSTSSPLDECRAEGHEFVMQPVRGGHNPCCEVCMHTIWRLVQWWRRCRVCGMRAHDKCAEEVKRVCAGVLSTRAKFELNTNLCEERSLAEQEYQCAECTAPICFDGVAEQEARLCDYSGELFCPNCHWNDVWSIPARIVHNLDSTPRPVCRAVKQLLAIIDHRPLIDINESTLSLIKFHKELRRVNELRRNFLLMKCYFVSCRTARRLRILQYLNAHSHFVDNSVMYSPKELRELCDGTLLPDLEQIHTVFRKHIEEECETCAGNGFFCELCDDINVDQKNKILYPFTENTRSCATCLAVYHKKCFERKSLNCPRCERRRKRTEIPKTLSSSDEKEAVRN
What are the official names of this protein?
Differentially expressed in FDCP 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the DEF8 family.
Protein: HLDE_MARN8
Sequence: MLDLARLDQLQNASVLVIGDVMLDRYFIGDTNRISPEAPVPVVRVAHTEDRAGGAANVARNIAHLDGQAAILGIIGNDTDGRLLKDLLIKEKVHSELLELDDARTISKTRIISRHQQMVRLDMEDTFPVAQAESVKQRYAELIEQYNTVIISDYAKGTLACVGDLIQAARKAGKQVLVDPKSKDFSLYRGATVITPNLSEFKAAGGDASSDDAMLSSARAMLTDAGIDTMLLTRSEQGMSLITPTEHHHFPAEVLEVSDVTGAGDTVIATLGTLLSAGFDLKDAAWLSNLAAGIVVAKLGAATVSPEELAARASHQWSAKTSGYHPSVEQSLLHIDYARQQGERIVFTNGCFDILHAGHVRYLAQARALGDRLVVGLNSDASVRRLKGEERPVNSLEDRMEVLSALACVDWVIPFGDNTVENDTPEQLIKRVNPQVLAKGGDYSIDTIVGADFVQENGGEVAILPTVEGRSTTGLIKKVRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: HIS1_ARTS2
Sequence: MLRVAVPNKGSLSEAASAMLSEAGYRQRRDTRELVMVDPDNDIEFFFLRPRDIAVYVGRGTLDVGITGRDLLLDAEVEAEELLPLGFAASTFRFAGPVGDFTKVEELEGKRLATSYDGLLRGYLAERGINAKVVRLDGAVESSVRLGVADAIADVVETGNTLKAAGMEIFGEPILKSEAVLIRRTGQEGAANGTAKEIEVLIRRLQGVLVARQYVLMDYDIRKELVEQAAALTPGLESPTVSPLRDSDWVAVRSMVPKKETNRIMDELYDLGARAILVSSIHACRI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK_RICTY
Sequence: MALIIQKFGGTSVANIERIKKLVPIIKAEITKNNQVIVVVSAMAGVTNQLVTLCSEVSSLNKISQFAEYDVALSSGEIVTAALLALALQEEEIQAQSLLAWQLPILTNNNHSKALVEFITTDLLEKCLQLKIIPIIAGFQGINKSNRITTFGRGGSDTTAALIAAAMKADRCDIYTDVDGIFTADPRIIPNAKRIKEIDFLEMLELASSGAKVLHPRAVELVMRYKIDMRVLSTFLPNTEGTLITSKDTTPLVKSTYMDMEESAKNIKRSTKINIPDDTSGLTYKLPIELALQNRYNMENCIIRGITSNKNLLKVSVNTITLSFLQVANMITYNNNCIEFMQEIKNNIEYNFITNLTDKNNLQTLLTNCKNNKQIQNFTFDTEIATISLIGYGIKNDCKLLEMILSQLTQDNINVNMMQLSEVKITLLINDKDVEKTISNLYNLFKIS
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: HEMH_PELPD
Sequence: MVIDRTAVLLLQMGGPDSIEAVEPFLRNLFSDRDIIRIGPAFLQPLIARLIARRRSKRVAEQYRQIGGGSPLRKLTEQQAAELEKVLGEGYRCFVAMRYWKPDTSQALEAVVQAGITRIVALSLYPHYSRATSGSSFNELERVRARSATPFQVTCVRQFHDHPLYITSLCDRIGQALSGYADPGDVHLLFTAHGLPQSFIDSGDPYLDQIRATVALVMERFGGINHHLAFQSRAGPVKWLEPSTEKKIRELAGQGVKKLLMVPVSFVSDHIETLHEIDMQYRHEALELGIEDFRRVESLNSSPLFIDCLAELVRGGDRTEET
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTS1_ASPFU
Sequence: MASHIIGNRNSTPDASKSSLRPPSSSRNLGSHQLRASADMSGFPSPLSSRSIRPSSEVYYSQQSQAQNNAEDPLDRAAQQWLADIDQYETTLEEMAAATLDQDFKDELSAIEQWFRVLSEAERTAALYALLQQTTQVQIRFFIQVLQQMAKSHPMSGLLSPANFSEKDAMSNRLNDAMSKLNIDSSRNSLGRPPPSPGAKRNSGLDSSTINAMFPDAAAAIAKKKAEFTQQTGNAPPSNRNSAVYGDRSSLVAPTISAPDNTDNLGQPPASPWAQRGNEPQPPIARPKSSSGQQPMGQFSQASSGLRSPLPTQTATITAPEIEAPLLSPYNVGNASWASMTNTPMTATFGQQVHQPPNSQADMVANATAMKLAALSTVNNRIALDDARKYRRARSNDGQGRSSNTNVNQTIQGGLASPGLPGANHLVAGQLLNAQQLAALQAQQQAAMAGRRSRPTSPGIAMQGGALAAMGFTSPQNNGFLAAYDPNNPLLGNGLGALGLSQFGLGGHEGYLSDHSEVTRGRSPRGRRGSSKPPEDPTDPNLLKDIPSWLRSLRLHKYTDNLKDLKWTELIELDDKALEERGVNALGARNKMLKVFEQVKEAKSEGKLDSIA
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
What are the official names of this protein?
RNA-binding protein vts1.
What is the protein family that this protein belongs to?
Belongs to the VTS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body.
Protein: GATC_SOLUE
Sequence: MKITEKEVRYVAGLANLNLTEQEIARMQVDLDGILEHMARLNEIDTEGVAPMSQVLFEAEETATLRPDSPIPPLGNQAAMANAPQSGAGYFKVPKVIER
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HA22E_ARATH
Sequence: MTKLWTSLSALHSLAGPVVMLLYPLYASVIAIESPSKVDDEQWLAYWILYSFLTLSELILQSLLEWIPIWYTAKLVFVAWLVLPQFRGAAFIYNKVVREQFKKYGILKPKVEHQAE
What are the official names of this protein?
HVA22-like protein e, AtHVA22e.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HYPAA_POMPR
Sequence: GIPCAESCVYIPCTITALLGCSCKNKVCYN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide hypa-A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: NCAP_EBOSU
Sequence: MDKRVRGSWALGGQSEVDLDYHKILTAGLSVQQGIVRQRVIPVYVVSDLEGICQHIIQAFEAGVDFQDNADSFLLLLCLHHAYQGDHRLFLKSDAVQYLEGHGFRFEVREKENVHRLDELLPNVTGGKNLRRTLAAMPEEETTEANAGQFLSFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQYPTSWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDTVISNSVAQARFSGLLIVKTVLDHILQKTDLGVRLHPLARTAKVKNEVSSFKAALGSLAKHGEYAPFARLLNLSGVNNLEHGLYPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAATEAEKQLQQYAETRELDNLGLDEQEKKILMSFHQKKNEISFQQTNAMVTLRKERLAKLTEAITTASKIKVGDRYPDDNDIPFPGPIYDETHPNPSDDNPDDSRDTTIPGGVVDPYDDESNNYPDYEDSAEGTTGDLDLFNLDDDDDDSQPGPPDRGQSKERAARTHGLQDPTLDGAKKVPELTPGSHQPGNLHITKPGSNTNQPQGNMSSTLQSMTPIQEESEPDDQKDDDDESLTSLDSEGDEDVESVSGENNPTVAPPAPVYKDTGVDTNQQNGPSNAVDGQGSESEALPINPEKGSALEETYYHLLKTQGPFEAINYYHLMSDEPIAFSTESGKEYIFPDSLEEAYPPWLSEKEALEKENRYLVIDGQQFLWPVMSLQDKFLAVLQHD
What is the function of this protein?
Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response.  VP35 binds to and stabilizes monomeric NP, keeping it soluble.  Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released.  The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication.  The nucleocapsid is helical with a pitch of 10. 81 NP per turn and a diameter of about 22nm.  Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid.  Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription.  Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the filoviruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MET24_MOUSE
Sequence: MATVKPPGRGCGALPRWLLGAALLLGLRLCMELRHAGSGPPGRGDSPGPPRTHLLSAPGSPRGARRRQVTYVRSGRRVLPRGGGSTTSPEPSCCAQGGLLRRKGSRWHIELQPWAGPSRSLDEEASRFLSYISTTQIACDHMGTDSLATDSSPAPKPWLVCLDDRFGLAHQIRSKRCRLYSLGLGSDDTHFEVSMANGGCEVHRFDPSVKSAHVLERQGLWHHRLSIDWRDPHPAVAAQKPHGNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLVFEIHLHWPGFEVSGSESGVVRFWYSLLKELERKHFRLFHTYKDLTKPQLFLKKDLFNASSCYTLSWVNTKWR
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Probable methyltransferase-like protein 24.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DHOM_SYNY3
Sequence: MTVKIGLLGLGTVGSGTVEILQDPQGRSPLLKAIEVKAVGVRSLDKPRQVNLPPEVLTTDLEAIVTDPDIAIVVELMGGLEPARSLILQAIAHKKHIVTANKAVIARYGPEIYEAANQHGVYVLLEAAVGGGIPIIKPLKQSLGGNRIQSIVGILNGTTNYILSRMTSEGADFDEVLTAAQQLGYAEADPSADVDGLDAADKIAILASLGFGGRVKREDVACEGIRSVSAVDIAYADRLGFVIKLLAIADGNAGEDSEALQLRVHPTLIAKDHPLASVNGVYNGVLVTGDPLGQVMFYGRGAGAGPTASAVVSDVINIVGIITSSDENPALDPLLSCTHQHYCQVSPIEDLVTRFYCRFLCADVPGVIGHLGMGFGNHGVSLESLVQIGFTDGCAEIVVVTHDVREGDYRAALEEISQLEAVKEIPSVIRVLS
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: RECA_CROS8
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRTMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQRAGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVLVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGEEVVGSETRVKVVKNKVAAPFKQAEFQILYGEGINFYGELVDLGVKHKLIEKAGAWYSYNGEKIGQGKANATNFLKENKPMADEIEKKLRDMLLNNQDSTPDFTVDDNDGGVEETNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_HAEIG
Sequence: MATIKDVAKMAGVSTTTVSHVINKTRFVAKDTEEAVLSAIKQLNYSPSAVARSLKVNTTKSIGMIVTTSEAPYFAEIIHSVEEHCYRQGYSLFLCNTQNDPEKVKNHLEMLAKKRVDGLLVMCSEYTQDSLDLLSSFSTIPMVVMDWGPNANTDVIDDHSFDGGYLATKHLIECGHKKIGIICGELNKTTARTRYEGFEKAMEEAKLTINPSWVLEGAFEPEDGYECMNRLLTQEELPTALFCCNDVMALGAISALTEKCLRVPEDMSIIGYDDIHASRFYAPPLTTIHQSKLRLGRQAVNILLERITHKDEGVQQYSRIDITPELIIRKSVKSIL
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: CAHEM_HEMLE
Sequence: MRASLFIVIFVVSFITISCLSTDDEEARWIEKRGDCLPHLKLCKADKDCCSKKCKRRGTNPEKRCR
What is the function of this protein?
This toxin stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (20% and 38% of the full conductance state have been found) (PubMed:17291197, PubMed:27114612).  It promotes an increase in the opening probability at intermediate concentration (PubMed:17291197).  Furthermore, it triggers calcium release from sarcoplasmic vesicles (68 nM are enough to induce a sharp release, and 45% of the total calcium is released after toxin (100 nM) addition) probably by acting as a cell-penetrating peptide (CPP) (PubMed:17291197, PubMed:27114612).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 (EC(50)=6. 9-71 nM) (PubMed:17291197, PubMed:27114612).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:27114612).  It binds a different site as ryanodine (By similarity).  It acts synergistically with caffeine (By similarity).  In vivo, intracerebroventricular injection into mice induces neurotoxic symptoms, followed by death (PubMed:17291197).
What are the official names of this protein?
Hemicalcin, HCa, HmCa.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMG_SHEPC
Sequence: MTTQFSVAGVELELLRYPAQQESNLQAWDAADEHLLKSLIESEQAAVPTAIVNDSFGALSCGLSKLHPSWPLFVETDARTSFLGTEQNHGRNQLPMDNLQRFTSRDTLPENLALVLMKLPKNLSYFAHQLTRLSQVLPAGTRVLVAAKAKSINSALLDIFAKHLGPASASLAWKNTRVITCVSDGKPRPLAKEVTWAVPEYQLEISNLSNVFAANKLDIGARIMLENLPKGNFKSIVDLGCGNGVLGLRTAQLSPEADIHFIDDSEMAVASAKANWARNQLPADKGHFYWDDCMTHLPEEVQPDLVLCNPPFHQGEAITDHIAWQMFLDARRRLKEGGILHIVGNRHLAYHVKLQRLFKNCTTVASNGKFVILQAQKK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PROMP
Sequence: MPNSIFKKQLSPIKPGDPIDYKDVELLKKFITERGKILPRRMTGLTSKQQRDLTLAVKRARIVALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CELF3_DANRE
Sequence: MKEADAIKLFIGQIPRNLEEKDLKPIFEQFGKIYELTVIKDKYTGMHKGCAFLTYCARESALKAQNALHEQKTLPGMNRPIQVKPADSEGRGDRKLFVGMLGKQLSDADVRKMFEPFGSIEECTVLRGPDGASKGCAFVKYQSNAEAQAAISALHGSRTLPGASSSLVVKFADTEKERGIRRMQQVASQLGVISPMSLHLGAYNAYTQALVQQQALVAQSAYLSPVATVAAVQMQQLAALNPSSIIATPIASITPSSGTSTPPTIAATPVPALPPPIAVNSYPPVPAAPNGQSASEALYTNGVHPYQAQSPALDPLQQAYTGMQHYTATYPAAYGLVGQPFPHQPTLVAQQPQQPQQLQQREGPEGCNIFIYHLPQEFTDSEMLQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY
What is the function of this protein?
RNA-binding protein that may be involved in the regulation of pre-mRNA alternative splicing.
What are the official names of this protein?
CUGBP Elav-like family member 3, CELF-3, Bruno-like protein 1, CUG-BP- and ETR-3-like factor 3, ELAV-type RNA-binding protein 1, ETR-1, RNA-binding protein BRUNOL-1, Trinucleotide repeat-containing gene 4 protein.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FLIC_ECO27
Sequence: MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQASTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGQTITIDLKKIDSDTLGLNGFNVNGKGETANTAATLKDMSGFTAAAAPGGTVGVTQYTDKSAVASSVDILNAVAGADGNKVTTSADVGFGTPAAAVTYTYNKDTNSYSAASDDISSANLAAFLNPQARDTTKATVTIGGKDQDVNIDKSGNLTAADDGAVLYMDATGNLTKNNAGGDTQATLAKVATATGAKAATIQTDKGTFTSDGTAFDGASMSIDANTFANAVKNDTYTATVGAKTYSVTTGSAAADTAYMSNGVLSDTPPTYYAQADGSITTTEDAAAGKLVYKGSDGKLTTDTTSKAESTSDPLAALDDAISQIDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: FTSQ_NOVAD
Sequence: MAQTIKRGGKGVRRATAARSAQRKVQTARQQTGSVLDSVLRWLPFSEETLHRILMTLILAAAAGLVWTVAVMAGIPALVSEQAAIIASDAGFKVSHLEVRGVNRMNEAKIYERILGQNDRAMTTLDLAALRDELNQLPWVKDARVSRKLPDTLVIDIVERTPHAVLRKPDRMVLIDDTGVELESVRADRAKGMLVLSGMGVGQRVEDLTRLLDAAPALKPQVSEAEWVGNRRWNLTFKTGQVLALPEGDETAASALLSFARMDGVNRLLGGKVAAFDMRAPDRIYMRVPGHADEVAAEKRAEEQARAEAKRAASAKSDEG
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.