PharMolix/UniProtQA huggingface dataset:
Protein: RL35_CANAL
Sequence: MAGVKTFELRTKSKEQLESQLVELKQELATLKVQKLQRPSLPRIHTVRKNIARVLTVINLNQRENVRAFYAGKKYIPKDLRAKKTRALRRKLTKFEASQETEKARKQRIAFPQRKFAIKA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: FOLD_DESAH
Sequence: MAEVLKGKPVADALKAELTKNIEALKKDKGITPKLGIIRVGARPDDLFYEGGAKKTCAAVGMDCEIFEYPEDIDQASFEKAVTEVGAKKDVNGILMFSPLPKNLDERKIRTLIPVEKDVDCLTTGGAAKVFTDDATGFPPCTPTACMEMLHFYDIPIKGKKCVVVGRSLVVGKPLAMLLLREHGTVTICHSRTENLPGVCQDADILIAAVGRAKMVKADFVKKGQIVIDVGINADPDRPGKYCGDVDFETVEPVVTKITPVPAGVGSVTTSVLCKQTFMACQMQNA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BIOH_SALDC
Sequence: MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S41A3_MOUSE
Sequence: MEGTEARQRRLEGCGRLKELGPLPSHDAGRLPKASEEGHLAVSESQLVDAKSLEAPPGRETSLIIGFQVVIPFLLAGVGLSWAGLLLNYFQHWPVFKDVKDLMTLVPPLVGLKGNLEMTLASRLSTSANTGQIDDRQERYKIISSNLAVVQVQATVVGLLAAVASLMLGTVSHEEFDWSKVALLCTSSVITAFLAALALGILMICIVIGARKFGVNPDNIATPIAASLGDLITLSILALMSSFFYSHKDTWYLTPLVCVGFLALTPLWLFIAKQNPPIMKILKYGWFPIILAMIISSFGGLILSKTISKHEFKGMAVLTPVMCGVGGNLVAIQTSRISTFLHMWSTPGVLPVQMKRFWPNPCFIFCSSEINSVSARVLLFLVVPGHLIFFYLICLVEGQSVTNSKIFILLYLVAGVVQVVILLYLAEVTVRLTWHQALDPDNHCIPYLTGLGDLLGTSLLALCFFLDWLLRGRANLQELVSELVSVPP
What is the function of this protein?
Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the mitochondrial inner membrane.
What are the official names of this protein?
Solute carrier family 41 member 3.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BID_RAT
Sequence: MDSEVSNGSGLGAEHITNLLVFGFLRNNDRDFHQELEVLGQELPVQVYLEGDREDELQTDGSRASRSFYHGRIEPDSESQDEVIHNIARHLAQAGDELDHSIQPTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTSFPRDMENDKAMLIMTMLLAKKVASHAPSLLRDVFRTTVNFINQNLFSYVRDLVRNEMD
What is the function of this protein?
Induces caspase activation and apoptosis (By similarity).  Allows the release of cytochrome c (By similarity).
What are the official names of this protein?
BH3-interacting domain death agonist, p22 BID, BID.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion membrane. Mitochondrion outer membrane. Note=When uncleaved, it is predominantly cytoplasmic (By similarity). SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p15]: Mitochondrion membrane. Note=Translocates to mitochondria as an integral membrane protein. SUBCELLULAR LOCATION: [BH3-interacting domain death agonist p13]: Mitochondrion membrane. Note=Associated with the mitochondrial membrane.
Protein: TRPB_BRUMB
Sequence: MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYVGASDVERQKPNVFRMKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIVAAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLLGMDI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: POTA_VIBVY
Sequence: MGEIQTLNAKQNAGQPVIRLSGISKSFDGKEIIGNLNLDVNHGEFLTILGPSGCGKTTVLRMIAGFETADNGQITIDNQDVTNVPAEQRHVNTVFQSYALFPHMTVFDNVAFGLRMQKVPAAEIEPRVMDALKMVRLESMAQRKPHQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQIELKQLQRQLGITFIFVTHDQEEALSMSDRIIVMRSGVIEQDGSPREIYEDPKNLFVARFIGEINVFEATAKERLDENRIRAEIEGVDSVVYFDQPVTEGQKLQVLLRPEDLRIEEIKESEEKGIVGHVTERTYKGMTLDSVIETESGMRVMVSEFFNEDDPDVDHSLGQKVAITWVESWEVVLSDEQEI
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADK_VEREI
Sequence: MTSNFRHVALIGKYQASSAGAIGESSRQALDGIARFLQHQGCSVAIEVETASNTGLLHYPSLTVEDIGARCDLGLVVGGDGTMLGIGRRLARFGTPLVGINQGRLGFITDIPFDTYQATLPPMLEGDYEEDSRPLIQACVMRAGQVVFEALAMNDVVVNRGATAGMVELRVEVGGRFVANQRADGLIIASPTGSTAYSLSAGGPMLHPSIPGWVLVPIAPHTLSNRPIVLSDATEVAVEVVSGRDVSASFDMQSLASLLHGDRILLSRSAHCVRFLHPQGWNYFATLRKKLRWNDGDP
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_CHLL3
Sequence: MAKEEAIEIEGVILEALPNAQFKVKLENSLEVLAHVSGKIRMHYIRILPGDKVKVQISPYDISKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1514_METJA
Sequence: MEYVFVYGSLRKGFWNHEPYLKNSKFIGKGKTKEKYAMYVNIIPYVVENEKISHIVGEVYEVDEKTLKRIDCLEGHPDYYRRKKVSIILDSGKEIEAWLYFYPESCGILVESGDYKDYRG
What is the function of this protein?
Putative gamma-glutamylcyclotransferase.
What are the official names of this protein?
Putative gamma-glutamylcyclotransferase MJ1514.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: RL11_RUMCH
Sequence: MAKKIAGYVKLQIPAGKATPAPPVGPALGQHGVNIMGFCKEFNERTAKDAGLVIPVVITVYADRSFSFITKTPPAAVLLKKACKIESGSGKPNKDKVAKITMDEVRKIAEQKMPDLNAASVDAATKMIAGTARSMGIVVVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HOLIN_BPPZA
Sequence: MTMIAWMQHFLETDETKLIYWLTFLMVCMVVDTVLGVLFAKLNPNIKFSSFKIKTGVLIKVSEMILALLAVPFAVPFPAGLPLLYTVYTALCVSEIYSIFGHLRLVDDKSDFLEILENFFKRTSGKNKEDK
What is the function of this protein?
Counteracts the aggregation of the holin molecules and thus of pore formation.
What are the official names of this protein?
Antiholin, Gene product 14, gp14, Lysis inhibitor 14-131, Protein p14.
What is the protein family that this protein belongs to?
Belongs to the bacteriophage holin family. phi29likevirus holin subfamily.
What are the subcellular locations of this protein?
Host cell inner membrane; Multi-pass membrane protein. Note=Classified as a class I holin.
Protein: NTCP4_HUMAN
Sequence: MDGNDNVTLLFAPLLRDNYTLAPNASSLGPGTDLALAPASSAGPGPGLSLGPGPSFGFSPGPTPTPEPTTSGLAGGAASHGPSPFPRPWAPHALPFWDTPLNHGLNVFVGAALCITMLGLGCTVDVNHFGAHVRRPVGALLAALCQFGLLPLLAFLLALAFKLDEVAAVAVLLCGCCPGGNLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSWAWINTPIVQLLPLGTVTLTLCSTLIPIGLGVFIRYKYSRVADYIVKVSLWSLLVTLVVLFIMTGTMLGPELLASIPAAVYVIAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPPQFIGSMYMFPLLYALFQSAEAGIFVLIYKMYGSEMLHKRDPLDEDEDTDISYKKLKEEEMADTSYGTVKAENIIMMETAQTSL
What is the function of this protein?
Transporter for bile acids.
What are the official names of this protein?
Sodium/bile acid cotransporter 4, Na(+)/bile acid cotransporter 4, Solute carrier family 10 member 4.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROA_VIBA3
Sequence: MESLTLQPIQKVSGEVNLPGSKSVSNRALLLAALSTGTTRLTNLLDSDDIRHMLNALTQLGVDYQLSADKTVCEVTGVGGAFSSDKALELFLGNAGTAMRPLAAALCLGRGEYVLTGEPRMKERPIGHLVTALREAGADVEYLENENYPPLKITGTGLKSGTVSIDGSISSQFLTAFLMAAPLAEGEVTIKIEGELVSKPYIDITLHIMKQFGVDVINNDYQEFVIPTGQSYTAPGDFLVEGDASSASYFLAAAAIKGGEIKVTGIGKNSIQGDIQFADALEKMGAEIEWGDDYVISRCGELKGIDMDYNHIPDAAMTIATTALFAKGTTAIRNVYNWRVKETDRLAAMATELRKVGAEVEEGEDYIIVNPVAELTHAAIDTYDDHRMAMCFSLVALSDTPVTINDPGCTSKTFPDYFDKLKMLSL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_BORBR
Sequence: MIVRNVKDVMGTEDEVRTDTWVSRRVLLKKDGMGFSFHETTIFPGTRTHIHYKNHLEAVWCIEGDGSIETIADGKTYELGPGVVYALNENDEHWLCGGKQPLRVICVFNPPLTGQEVHDAEGVYALVEEAA
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: NDK_SYNPW
Sequence: MASERTFIAIKPDGVQRGLIGEILGRFERKGFKLVGLKQLTPSRELAEQHYGVHKERPFFAGLVDFITSGPVVAMVWEGDGVIASARKLIGATKPLEAEPGTIRGDLAINIGRNVIHGSDAPETAQFEIGLWFQASELSDWTPSDQGWRTEG
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPHRB_HUMAN
Sequence: MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP
What is the function of this protein?
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (PubMed:18794847).  Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity).
What are the official names of this protein?
Golgi pH regulator B, Protein GPR89B.
What is the protein family that this protein belongs to?
Belongs to the Golgi pH regulator (TC 1.A.38) family.
Protein: SYR_SOLM1
Sequence: MRATAILRDLLASALENQGIAWPVKTTIEPPRDKAHGDLATNVAMMASKAAKKPPRELAESLRQALAADPRLASVEVAGPGFLNVAFTPAFWQETVCDVAKAGDGYGLLDIGQGVKIQVEFVSANPTGPLHIGHGRGAAVGDSLARVLRAAGFTVETEYYINDAGRQMRILGMSILYRYKELIGEPVTEPEDYYRGEYVIPLAQDMIDAHGRKLLEMPEAEATDICRLHGEREILAGIKKDLEDFRVHHDVWFPESTLLAAGAVDAAFNELRDKKLAYDQDGAFWFASTAFGDDKDRVLVKSGGELTYFASDIAYHADKFRRGFDVVVDIWGADHHGYVPRMKACVSALGRDPEASLKVILVQLVNLLKGGEQIAMSTRAGKFETLADVVKEVGADSARFMFLSRKSDSHLDFDLDAVKEKSMDNPVYYVQYAHARVRSLFAKAQERGQAVAETSPELLALLTTDEDLELLKLLEQYPDTVAAAARTFSPHLVSFYLRDLAGRLHRYYTVNPVLTAGSDDLASARLRLLDAVAQTIKNGLDLLGVSAPDKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_DICDI
Sequence: MEGDAPVIAANPLEKNTDPMVALQKVIKESLAVQGVARGLHETVKALDKRTARLCVLASNCDEPNFVRLVKALATEHNIPLIEVPDNKALGEWAGLCKLDKDLAARKVVACSTLVIKTFGKESDDYKFLMEYISKQ
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
Protein: TRBP2_XENTR
Sequence: MSENGDCENQTSSGFPSIEQMLASSPGKTPISLLQEYGTRVGKTPVYDLLKAEGQAHQPNFTFRVSVGDINCTGQGPSKKAAKHKAAEVALSLLKGGDMFGMMCEENSVMLSVEQPVELREVADVSPPPTNRNHTIEMKPPLSAQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFLEIGSGTSKKLAKRNAAAKMLLQIHRVPAEHRESGETEPEEDQFSMGKLDGSRGRGTACTWDSLRNSSGEKILHLRSNPLTILSSGFCSLLQDLSEEQSFQISYLDIDEPSLSGLYQCLVELSTQPTTVCHGSATTRDAARANAAHNALQYLKIMAGGK
What is the function of this protein?
Required for formation of the RNA induced silencing complex (RISC).  Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2.  Within the RLC/miRLC, dicer1 and tarbp2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto ago2.  ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from dicer1 and tarbp2.  May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by dicer1.
What are the official names of this protein?
RISC-loading complex subunit tarbp2.
What is the protein family that this protein belongs to?
Belongs to the TARBP2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y333_METJA
Sequence: MNKEKYGDNMMTDSDSKQAIFIIGVQGKEIKNVEQLMQELSKIVNEGSIYRYSKETGLGKGTLHKIKNNELQDPRISTVLKLLKASGKRLVIIDEW
What are the official names of this protein?
Uncharacterized protein MJ0333.
Protein: HSLU_SINFN
Sequence: MTNFSPREIVSELDRYIIGQKDAKRAVAIALRNRWRRQQLSDELRDEVMPKNILMIGPTGVGKTEISRRLAKLAGAPFVKVEATKFTEVGYVGRDVEQIVRDLVEVGITLVREKKRAEVKAKAHQNAEERVLDALVGTTASPATRDSFRKKLRANELDEKEIEIDIAETGAPGGFEIPGMPGANIGVLNLSEMFGKALGGRTRKVKTTVKDSYELLVNDESDKLLDNEQIQREAMAAAENDGIVFLDEIDKIAARDGGIGAGVSREGVQRDLLPLVEGTTVATKYGPMKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELRALTKEDFRRILTETEASLIRQYKALLETEGVALDFTEDAIDALAEVAVQLNANVENIGARRLQTVMERVLDDISFNAPDRGGDTLMIDADYVRKHVGDLAANTDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG57_BPML5
Sequence: MYRGCLAIPYMRWSPWRHWTVAAIRYRRIDGGTPKYLSMPGEKDRLYNTYALTKYSKDMAICEGELDTITAELCGLPTVGLSGAQKWKPYFRELFLGYRNVNILADGDDAGMEFARSVAKTLPNARIIPMPEGEDVNSLVTSQGKAALLERI
What are the official names of this protein?
Gene 57 protein, Gp57.
Protein: DPO3_STRPQ
Sequence: MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTIDMVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGVWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVELHAHTNMSTMDALLTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKACPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGAEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III polC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_NITOC
Sequence: MIKQRTLKNVIRATGVGLHTGDIVYLTLRPAAVDTGIVFRRVDLDPPVEIKAREENVGDTTLSSTLVKEGVRIATVEHLLSAFAGLGIDNAYVDLNASEVPIMDGSAGPFVFLIQSAGIVQQEAPKRFILIKKTLLMEEEGKWARFEPFDGFKVSFVIDFDHPAFKGRPQGVEIDFSSTSFVKEVSRARTFGFMKDIERLREANLALGGSLNNAVVVDDYRVINEDGLRYEDEFARHKILDAIGDLYLLGHTLIGAFSGYKSGHALNNKLLCALMADKSAWEIVTFEDDETAAPILFTRPLTAA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PICAL_CAEEL
Sequence: MQTIEKALHQPMPFTTGGQTISDRLTAAKHSLAGSQLGKTICKATTEEVMAPKKKHLDYLLHCTNEPNVSIPSMANLLIERTQNPNWTVVYKALITIHNIMCYGNERFSQYLASCNTTFNLTAFVDKVGGAGGYDMSTHVRRYAKYIGEKINTYRMCAFDFCKVKRGREDGLLRTMHTDKLLKTIPILQNQIDALLEFSVTTSELNNGVINCSFILLFRDLIRLFACYNDGIINVLEKYFDMNKKQCRDALDTYKSFLTRLDKVAEFLRVAESVGIDRGEIPDLTRAPASLLEALEAHLIHLEGGKAPPPTQQHVAPHQFTTGFAFSQQPQPALGDAERQRYIELEQERLRQFEDQKKSINSANPFANDVASAAPAPATSAAQPDLLDMFQSSAAPAPQTADVTNPFGNFAAPSAFPTNVPPPAAHSAPFGVQPAPQHSAAPFYANLHQAPPMQSQAPNGHQAAPFGYPNAHPDDLARMTAQMSLNQQGAPAGWNTTTSAVSNNPFGATSAPQPMYTAPMGMYQQPFGAQPMWNPAMAAYGQQYGYGQPVPPQQQHQIQLVHAAMAAKNAAQAQQAQAASADPFGL
What is the function of this protein?
Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly.  May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage.  Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.  Required for the efficient targeting of the synaptic vesicle protein synaptobrevin.
What are the official names of this protein?
Phosphatidylinositol-binding clathrin assembly protein unc-11, AP180-like adaptor protein, Uncoordinated protein 11.
What is the protein family that this protein belongs to?
Belongs to the PICALM/SNAP91 family.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: AROB_COXB1
Sequence: MKTERVNVNVNNQPYPIYIGENLLQDKSLLQRHVKGRQVMIVSNETIAAFYLDPLKAIYQDFQCDTFILPDGEQYKTLEYWERILHKLASCNHHRDTTLIALGGGVVGDITGFAAACYQRGVDFIQVPTTLLAQVDASIGGKTAVNHPVGKNLIGAFHQPKAVIIDLNTLNTLPEREFKAGMAEIVKAALIKDEKFFTDLENKMSDLLQRNFIFLQAVIKRAAEIKRDIVNADEKERSGERALLNLGHTFAHAIERLLGYGQWLHGEAVSAGLVLAAQLSHRKNLLDFESLQRICRLLTQISLPIHFPKSINADELLSAMYMDKKVANERLHLILLEDLGHAVVSDQVDDRELKSFLENG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJ6_SCHPO
Sequence: MVTASSSVRVSNEDECFIYDIEQLKDNVVVSYSTGSWSCFDKGTLLEIFKVPKAHTNITGIISCDQLNGVITCGSEGEIHLWDIRSQAKSAVRSWTQQSTPFTCIALNKKNQFATGSELTRSLASVQLWDVRSEQKLIRQWNDAHNDDITHLQFHPKDNELLLTGSVDGLVSLLDTTKEEDSTDPEEDPLLHVINHGASIHLAKFVSKKRVMVLSHMESYAMYKLKRDKDEKTWSSNELFSIDDLRAELSCSYVINEVSTSDKQFCALAFGDFSNHETKFVLVDTSTGELKKEPTKLERASEEICRAISFDVKNDVYYSGGEDGLLQAFRV
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C63.06.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.