PharMolix/UniProtQA huggingface dataset:
Protein: YCIB_MAGMM
Sequence: MRFALELLAIVVFFVVYKLDGIYSATAALIIMVLLNVFYHWFKHRHVPSMMWITLILVMLFGGATLIFHDPLFIKWKPSILQWVLASGFLASHLIGKRVLVARMLDNQISMPSLHWRRLNAAWVLFLLFSGALNLYVAYTFSEEIWVSFKLFGLMGLTILFLIGQAFYMSRHGSEVRVEERKEGMIEAEETVENRPE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HPAB2_PSESM
Sequence: MAGINRAGPSGAYFVGHTDPEPVSGQAHGSGSGASSSNSPQVQPRPSNTPPSNAPAPPPTGRERLSRSTALSRQTREWLEQGMPTAEDASVRRRPQVTADAATPRAEARRTPEATADASAPRRGAVAHANSIVQQLVSEGADISHTRNMLRNAMNGDAVAFSRVEQNIFRQHFPNMPMHGISRDSELAIELRGALRRAVHQQAASAPVRSPTPTPASPAASSSGSSQRSLFGRFARLMAPNQGRSSNTAASQTPVDRSPPRVNQRPIRVDRAAMRNRGNDEADAALRGLVQQGVNLEHLRTALERHVMQRLPIPLDIGSALQNVGINPSIDLGESLVQHPLLNLNVALNRMLGLRPSAERAPRPAVPVAPATASRRPDGTRATRLRVMPEREDYENNVAYGVRLLNLNPGVGVRQAVAAFVTDRAERPAVVANIRAALDPIASQFSQLRTISKADAESEELGFKDAADHHTDDVTHCLFGGELSLSNPDQQVIGLAGNPTDTSQPYSQEGNKDLAFMDMKKLAQFLAGKPEHPMTRETLNAENIAKYAFRIVP
What is the function of this protein?
Effector protein involved in gene-for-gene resistance in tomato plants.  It is recognized by the host Pto resistance protein and elicits Pto and Prf-dependent hypersensitive response (HR) and programmed cell death (PCD), resulting in host immunity.  In susceptible plants, acts as a virulence factor by suppressing PCD and HR-based plant immunity.  This function requires its E3 ubiquitin ligase activity probably by recruiting E2 enzymes and transferring ubiquitin molecules to cellular proteins involved in regulation of PCD and targeting them for degradation.  Also, induces expression of host genes involved in ethylene biosynthesis and signaling, in particular ACO1 and ACO2, encoding the ethylene-forming enzyme ACC oxidase.
What are the official names of this protein?
Effector protein HopAB2, Avirulence protein AvrPtoB.
What is the protein family that this protein belongs to?
Belongs to the HopAB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS). Localized to the plant cell cytoplasm.
Protein: S35A3_CAEEL
Sequence: MNRANDTSSNLKLISLVVLIVQTTALVLTLRYSQTQKSEGPRYLSSTAVVCAEIIKLITCFFVIYRNNGYRFSGMLNELNREIFASPQTRADSLKVAVPAIMYVIQNNLLFFALKKLDAATYQVTYQLKILTTAIFSVTMLGKSLHRYNWMALILLTAGVALVQYPSGDSTTSKSTAAEHDASDNILGLGAVLAACFSSGFAGVYFEKILKTSKVSLWIRNIQLAFFSVFGALLVCWLYDWQAISDDGFLRGYNGVIWIVVLLQAYGGLVIALVVKYADNILKGFAVSLSIILSSFTSWLVLGDLTITTTFAIGATVVIFATFLYGHEPKSTPAEAHNA
What is the function of this protein?
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus (PubMed:17060606).  UDP-N-acetylgalactosamine (UDP-GalNAc) transporter in the Golgi apparatus (PubMed:17060606).  Apparently transports UDP-GlcNAc and UDP-GalNAc simultaneously, and independently, by an unknown mechanism (PubMed:17060606).  Functions redundantly with nucleotide sugar transporter srf-3 (PubMed:17652078).  May be involved in gonadal development (PubMed:17652078).
What are the official names of this protein?
UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine transporter nstp-4, Nucleotide sugar transporter protein nstp-4, Solute carrier family 35 protein nstp-4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
Protein: RF1_SYNE7
Sequence: MAEPYLIEKLQSVEQTFQDLTRRLADPEIATDPREFQRVARMRSSMEELVTTYEEWKQRDAELKGAREILRESSGDPELREMAALEVNELEALLVSLEERLKILLLPRDPNDDKNIMLEIRAGTGGDEASLWAGDLLRMYSRYAESQGWRVKLLSESTGELGGYKEAILEIQGESVYSKLKFEAGVHRVQRVPATEAGGRVHTSTATVAIMPEVDEVEVSIDPKDIELTTARSGGAGGQNVNKVETAVDLFHKPTGIRIFCTEERSQLQNRERAMQILRAKLYEMKLQEQQEAVSSMRRSQVGTGSRSEKIRTYNYKDNRATDHRLGLNFSLNPVLEGEIEEVIQACISKDQTEQLAQMAQDQEAAKV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL2_CANLF
Sequence: MYKMQLLSCIALTLVLVANSAPITSSSTKETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPKKATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNMNVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFSTLT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_NEIMA
Sequence: MHKIPKGTALAFDFGEARIGVAQGDAELGLSHPLATVTGGSNDEKFAAIAKLVQEWQPRYFVVGLPVHTDGTKHEMTHLSRKFGRRLNGRFNLPVYWVDERLSSVYAESLLSEAQVFGKKRKSVLDQVAAQAILHGFFEGGPAECFNGREG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_CERSK
Sequence: MADLNKLAEDIVGLTLLEAQELKTILKDKYGIEPAAGGAVMMAGPAAGAAAPAEEEKTEFDVVLTDAGANKINVIKEVRAITGLGLKEAKDLVEAGGKVKEAVAKADAEAMKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DNLJ_NATTJ
Sequence: MSKDIQKKVEALREKIEYHNHRYYVLDAPEISDQEFDALMNELIELEQTYPEYQSPDSPSQRVGGEPLDKFPRVSHEIPMLSLENAESQKGLLDFHQRVSKNTQKTDPVYVAELKIDGLALSLRYEQGILVRGATRGDGTTGEDITPNVKTVRSIPLKLSKPLDIEIRGEAFMSKASFERLNQEKAERGEDPFANPRNAAAGSLRQLDPKIPAKRDLDFFPYSVPYIRGENLDSHYSAVKELKDLGFKINPYIRKFETMEEVISYCEEWQEKRTKLPYEIDGVVIKLNDYNLQQQLGATSKNPRWAIAYKFPAEQAESQVNNIFINVGRTGALTPVVELEPVRIAGSTVKRASLHNEDILRQKDVRIGDRVIIQKAGDIIPEVVKVKEEARTGHEQPFVYPESCPVCKSEAKRINDEAILRCINPGCPAQAKERIIHFSSRDAMDIEGLGEKVVEKLYSHGLIKDVADIYYLAKNELSNLEGFGDKSAENLLQAIEESKKNPFNKLLYGLGIRLVGKRAAQLLAFEFEHLDNLMKAQIEDLTKINDIGPRMATSIVSFFQLEHTHNLIRKLKKAGVNMKEPTEQNKSSDPSLTGKLVVITGTFDNYTRRELTDLIEAKGAKVTSNVSSNTDFVLVGANPGSKRDKAQDLGLTIIEESDLEDFL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SDMA_METCA
Sequence: MSRSIRNQDVPELPRRRQVRTVGMSGNYWYVVEIDGRLKPRQVKRVRFWGQDIALFRDAAGELHAVEDRCPHRQLPLSQGFVEGGNLVCTYHGWKFDGCGRCTEIHHELGKGRTRLPRIRIRTYPVKAQWGLIWLFPGDPALADGTPLPTIPQLEGGRPWPFFPIDVTIKAHFSMIVENVCDFNHEYLHRHKRPFLQPILREWKQDADSVRVYYDTRFDGSPVAKLFMEGGARDLNEIEIWYQYPYQGSDIGGKYIHWLFMLPEDERTTRCFFVFLFGPIHVPIVNWKMPEFLRKPILWFTNKWYIEPLLGEDKWALELEQDGFERHPDAPQIELNPAISSFQRLSLEKWKAYQQSMERAGPKPAADPA
What is the function of this protein?
Participates in the biosynthesis of bacterial sterols (PubMed:29784781).  Together with SdmB, removes one methyl group from the C-4 position of 4,4-dimethylated steroid molecules (PubMed:29784781).  SdmA oxidizes the sterol 4beta-methyl group into first a hydroxyl, then an aldehyde and finally a carboxylic acid group (PubMed:29784781).
What are the official names of this protein?
4beta-methylsterol monooxygenase, Sterol demethylase protein A.
Protein: PARB_RICBR
Sequence: MKNKGLGRGLSSLLGEEVISTEKESLEIVQIINIDRIKPNENQPRKHFEYDKIKELSDSILNNGLLQPIIIDNSFQIIAGERRWRACKLAKISEIPVIIKNLDAKESMEIALIENIQRSDLTVMEEARGFKYLVENFNYTAEKLAERLGKSRSHIANLLRLNNLPQSIQNKLDENTLSMGHARCLINHEHAEIIANYVIDNDLNVRQTEELVRQWSQNEYTKYPDNNRIGKQLFKEKTEDNDLQSLVKILSEKFNIKVTIENYSLGGKLIFHYKDLKELDKILLELS
What is the function of this protein?
Involved in chromosome partition.  Localize to both poles of the predivisional cell following completion of DNA replication.  Binds to the DNA origin of replication (By similarity).
What are the official names of this protein?
Probable chromosome-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: MOAA_PYRFU
Sequence: MLIDKFGRPVTNLRISLTKECNLNCFYCHREGQQDGERTMTPEEIERIVRIASRLGIRNVKLTGGEPTVRPDIYEIIQRIRPYVVDLSMTTNGTTLYASAEKLKEAGLDRVNISLDTLDRKKYKMITGYDVLDQVLKGIRRATNLFYPVKLNMVVMRGINDDEIWDMIRFAGEVNAILQLIEIEVPREMENSQFFKDFFYPLKPLEEKFEKIAVEIRERKMHRRRKYFLPVDGKMVEVEVVRSMHNTTFCMNCTRLRLTADGYLKTCLLRKDDLIDILGPIRRGATDDELVKIFKRAVQLRKPYWIN
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TRM5_CANAW
Sequence: MSKFSPPINRNMVELDRSFFYKEVPLLAAYFPNPKFLGQFVKSCQNDILYVQTVKHIISMDDSKAILLRDDVKSISDLNPETQLKINEFGIILKPYTLKLDYSFWKSEEILKSILPENLIDDVPSGFSQAGHLAHINLRDEYKPFGKLIGQVILDKNPSVLTVVDKVNTIANKFRTFPLELLAGEPNYIVEQSESGCKFKFDFSKVYWNSRLSTEHERIIGKFNPGDVVGDVFGGVGPFAIPASKKNVIVLANDLNPESYKYLQENIKINKVEPFIKPFNLDGREFIRKAPELLLQWHNSQNGIIEKIIIKKVSIDDNKTKKIFERKPIIETTKIPKFYHHFVMNLPDSALTFLDEFIGLYGSNPQLKTDPEFKLPIIHVHCFEKFENNENPTPEELHNRVYEKICKLIQFPLNKKKVEFHEVRMVSPTKPMFCVSFELPEEVAFKQTK
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: Y9694_DICDI
Sequence: MDNNKKKDFFYFKPSEEIEEEIIDCFMENPVDENMFNQQQQQLQNNHENLEINEEYHQTINEMEDMIFTYSNTNISNDTNLSDNNVSDLIKLEIYNSNNINNNIYNTNNSNTNTNYNNNNNNNNNNNNNNNNNNNKNNNNNNNNNNSNSKIKRRNSIILDNVGTIIRIDTTNISSTKKRRIFK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0291786.
Protein: RS13_METPP
Sequence: MARIAGINIPPQKHAEIGLTAIYGIGRTTAQKICDSCGIARDKKIKDLTDGDLEKIREEVGRMTIEGDLRRETTINIKRLMDLGCYRGFRHRRGLPMRGQRTRTNARTRKGPRKSAAALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ACM3_MOUSE
Sequence: MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVSQLDSYNISQTSGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGTKRSSRRKYGGCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPDKDLGTMDVERNAHKLQAQKSMDDRDNCQKDFSKLPIQLESAVDTAKTSDTNSSVDKTTAALPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M3, Mm3 mAChR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.
Protein: ISPH_CUTAK
Sequence: MAVTGACTNKKLYLAAPRGYCAGVDRAVVTVEKALEVYGAPVYVRKQIVHNRHVVETLEGRGAIFVDELDEVPDDALVVFSAHGVSPQVKKEATDRGLRTIDATCPLVTKVHHEAKRFANQDTQILLIGHAGHEEVEGTTGEAPENITLVQTPADVDGLALDRDRPVAWLSQTTLSVDETVETVDRIRDLHPQLIDPPSDDICYATQNRQHAVKQMAPQCDLVIVVGSKNSSNTGRLVEVALESGAKASYRVDNAGEIEETWLDGVSTIGVTSGASVPEALVQGVIDLLISKGWPPAEEETLIEESLSFALPPQLRKRRTTAK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: APAG_PSEA7
Sequence: MSDTQHQVNVRVDTRYLPEQSAPEQNRFAFAYTVTIENRGEVSAQLLSRHWIITDGDGRTQEVRGAGVVGEQPLIAPGAQHTYTSGTVLATRVGSMRGSYQMLGSDGVAFDAAIPVFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: Y3868_ARATH
Sequence: MMKIIAAFLFLLVTTFVSRCLSADIESDKQALLEFASLVPHSRKLNWNSTIPICASWTGITCSKNNARVTALRLPGSGLYGPLPEKTFEKLDALRIISLRSNHLQGNIPSVILSLPFIRSLYFHENNFSGTIPPVLSHRLVNLDLSANSLSGNIPTSLQNLTQLTDLSLQNNSLSGPIPNLPPRLKYLNLSFNNLNGSVPSSVKSFPASSFQGNSLLCGAPLTPCPENTTAPSPSPTTPTEGPGTTNIGRGTAKKVLSTGAIVGIAVGGSVLLFIILAIITLCCAKKRDGGQDSTAVPKAKPGRSDNKAEEFGSGVQEAEKNKLVFFEGSSYNFDLEDLLRASAEVLGKGSYGTTYKAILEEGTTVVVKRLKEVAAGKREFEQQMEAVGRISPHVNVAPLRAYYFSKDEKLLVYDYYQGGNFSMLLHGNNEGGRAALDWETRLRICLEAARGISHIHSASGAKLLHGNIKSPNVLLTQELHVCVSDFGIAPLMSHHTLIPSRSLGYRAPEAIETRKHTQKSDVYSFGVLLLEMLTGKAAGKTTGHEEVVDLPKWVQSVVREEWTGEVFDVELIKQQHNVEEEMVQMLQIAMACVSKHPDSRPSMEEVVNMMEEIRPSGSGPGSGNRASSPEMIRSSDSPV
What are the official names of this protein?
Probable inactive receptor kinase At3g08680.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: Y4104_MAGSA
Sequence: MKNLGNLMKQAQQMQSKMAEMQATMAEMEVTGSSGAGMLQVTLNGKYELKKVKIDPSLVDPSDVEVLEDLILAAFNDAKAKAEAAMAEEMAKMTGGLNLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein amb4104.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ASR_ECOLC
Sequence: MKKVLALVVAAAMGLSSAAFAAETTTTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YNH1_SCHPO
Sequence: MLKKMPMSNKFENFYTLRQVSEVDKKPCFICYKPTKWVLITKTKLDFFYVCYNHLQDRGFATPISVIKSVTNKIDTNKLEAKDESKNVEKDATGNPQESKQEPNLEVQQTEKEKDVDSASAENESINSSSSSSKECSTQTQSKHYNLHRDIFQMRIRYHANRAAAEKTARLLQSGQGLPSPPSKPLP
What are the official names of this protein?
UPF0589 protein C32H8.01c.
What is the protein family that this protein belongs to?
Belongs to the UPF0589 family.
Protein: ENV_MLVFP
Sequence: MACSTLSKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGNHPLWTWWPDLTPDLCMLALSGPPHWGLEYRAPYSSPPGPPCCSGSSGNRAGCARDCDEPLTSLTPRCNTAWNRLKLDQVTHKSSGGFYVCPGSHRPRKAKSCGGPDSFYCASWGCETTGRAYWKPSSSWDYITVDNNLTTNQAAQVCKDNKWCNPLAIQFTNAGKQVTSWTIGHYWGLRLYVSGQDPGLTFGIRLKYQNLGPRVPIGPNPVLADQLSFPLPNPLPKPAKSPSASNSTPTLISPSPAPTQPPPAGTGDRLLNLVQGAYQALNLTNPDKTQECWLCLVSAPPYYEGVAVLGTYSNHTSAPANCSAGSQHKLTLSEVTGQGLCIGTVPKTHQALCNTTLKTGKGSYYLVAPAGTMWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSYRHKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLHAAVQDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLTQRQKLFESSQGWFEGLFNRSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPLEYEPQ
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: NIKC_STAAN
Sequence: MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENATKVNLSQTFEPISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIERLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISITVIKWMNYTRLTRSIVNSEMNKPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPPTPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDALRDRLLKQRGEYDESH
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Nickel import system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_MEIRU
Sequence: MENNEPVVETPEAQNDLPEVERLKGEVEFLKAELEASKNKFLRLYADFENYKKRMVQELEAAQRNGKFDAVRALLGTLDDLERALGFASVKPEDLIPGVRSVLENFTRSLKSLGVEAVPGVGAEFDPRYHEAIGAVEGEEGKVMHVYQQGFKYGDLLVRPARVVVGSGAKPEEAEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAF9_RAT
Sequence: MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPTVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKAPTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQAMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATPAVQNVLINPSLIGSKNILITTNMVSQNTANESANALKRKREEEDDDDDDDDDDYDNL
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex.  TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes.  Essential for cell viability.  May have a role in gene regulation associated with apoptosis.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 9, RNA polymerase II TBP-associated factor subunit G, Transcription initiation factor TFIID 31 kDa subunit, TAFII-31, TAFII31, Transcription initiation factor TFIID 32 kDa subunit, TAFII-32, TAFII32.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family.
What are the subcellular locations of this protein?
Nucleus.