PharMolix/UniProtQA huggingface dataset:
Protein: PXPA2_PSEPK
Sequence: MHNDKGDRVVERLLLNCDMGESFGSWRMGLDAEVMPYIDCANIACGYHAGDPGIMRRTVTLALEHGVTIGAHPAYPDLVGFGRRSMACSPEEIRDLLHYQIGALDGICKVLGGRVAYVKPHGALYNDMMADPLKLRTVLEAVAAYDSNLPLMLMATADNRAAQALGDEIGVPLWFEAFADRAYTASGHLLSRRLPGAVHHDPARVVEQAVRLARGETLLADDGSALQLAARTLCVHGDNDSSVAAVRQIRQALDGLEV
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A 2, 5-OPase subunit A 2, 5-oxoprolinase (ATP-hydrolyzing) subunit A 2.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: HOA1_CUPMC
Sequence: MNLQGKKITVHDMTLRDGMHPKRHMMTLEQMKSIACGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHSDEEYLGAVIPLMKQAKVSALLLPGIGTVDHLKMAKELGVHTIRVATHCTEADVSEQHIALARKLEMDTVGFLMMAHMNSPEGLVGQAKLMESYGANCVYITDSAGYMLPDDVRARLGAVREALKPETELGFHGHHNLAMGIANSIAAVECGATRIDAASAGLGAGAGNTPMEVLVAVCDRMGIQTGVDVWAIQDVAEDLVVPIMDFPIRIDRDSLTLGYAGVYGSFLLFAKRAERKYGVPAREILVELGRRGMVGGQEDMIEDTAITLAKARASKAQKVAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: XERC_CHLP8
Sequence: MTINRSRQPEDHEVARCRWLEPFLSHLQAARNVSPKTVTAYRCDLLQYFSFLKEQAGLDRLEAVEPERVEVADVRLFMGHLLDKGIQPRSIARKLASVKSFYRFLLETGRISSSPLSLVVTPRLDKKVPRFVSEEEARQLFRRFESQEDNAALQGDGKKAEVRQFETFRDRAVLEVLYGCGLRLSELIALERADVDLVHGFLKVTGKGRKQRIVPLGEPAVEALRKYFEVRRNFFRIPLERTGESSRVFVTSRGRQLYPMLVQRMTKRYLTPVSESEKKNPHILRHSFATHMLNGGADLKSVSEMLGHSSLTTTELYTHVTFSRLKEIYDKAHPGA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_ECO45
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKNV_BACSU
Sequence: MKQAKKQGVLERFYYSSDEIIEKPFNWAQMWRLLSYVKPYRKTILPLSFLTVLIGTAVKLVIPILIGVYVLDQAITGRNSELLIQLIFIISGLYVLNYAANVLRIRWMNQLGQHVIYDLRQHLFTHVQRLSHRFFDQRSAGSILVRIMNDINSLQELFTSGVINLLTDLLLLAGVIIILFTLSPELTIAIMVTLPIMFFISTSLRKKIRRSWQTVRLKQSKLNSHLNESIQGIRVTQAFTQEEENMAYFDGVNQENYESWREATRKNAMFRPLVEMTNAIGTAVLIWYGATLIMNETITIGVFVSFAFYLGMFWEPISRLGQVYNQLLMGMASSERIFEFLDEQPNVKEKPNAIHNEKINGEISFEEVEFSYDEKRKALHAVSFSIPAGSTLALVGHTGSGKTTIANLISRFYDAAGGTIKIDGIPIKDLSLASLRSQISIVLQDTFIFSGTIMENIRFGRPNASDEEVMKASQAVGADEFISDLAEGYATEVEERGSVLSAGQRQLISFARALLADPAIIILDEATASIDTETEVKIQQALKTLLKGRTAVMIAHRLSTIRDADRIIVLDHGRKIEEGNHDQLLAKGGIYAGLVKAQYSTAIE
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YknV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLCD_RAT
Sequence: MDLIGLLKSQFLCHLVFCYVFIASGLIVNAIQLCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTIYTDPKASPHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGWMWYFVEMIFCTRKWEQDRQTVAKSLLHLRDYPEKYLFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHLLPRTKGFAITVKCLRDVVPAVYDCTLNFRNNENPTLLGVLNGKKYHADCYVRRIPMEDIPEDEDKCSAWLHKLYQEKDAFQEEYYRTGVFPETPWVPPRRPWSLVNWLFWASLLLYPFFQFLVSMVSSGSSVTLASLVLIFCMASMGVRWMIGVTEIDKGSAYGNIDNKRKQTD
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase delta, 1-acylglycerol-3-phosphate O-acyltransferase 4, 1-AGP acyltransferase 4, 1-AGPAT 4, Lysophosphatidic acid acyltransferase delta, LPAAT-delta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRI72_XENLA
Sequence: MSTPQLMQGMQKDLTCQLCLELFRAPVTPECGHTFCQGCLTGVPKNQDQNGSTPCPTCQSPSRPETLQINRQLEHLVQSFKQVPQGHCLEHMDPLSVYCEQDKELICGVCASLGKHKGHNIITASEAFAKLKRQLPQQQVILQEARLKKEKTVAVLDRQVAEVQDTVSRFKGNVKHQLNAMRSYLNIMEASLGKEADKAESAATEALLVERKTMGHYLDQLRQMEGVLKDVEGQEQTEFLRKYCVVAARLNKILSESPPPGRLDIQLPIISDEFKFQVWRKMFRALMPALENMTFDPDTAQQYLVVSSEGKSVECADQKQSVSDEPNRFDKSNCLVSKQSFTEGEHYWEVIVEDKPRWALGIISETANRKGKLHATPSNGFWIIGCKEGKVYEAHTEQKEPRVLRVEGRPEKIGVYLSFSDGVVSFFDSSDEDNLKLLYTFNERFSGRLHPFFDVCWHDKGKNSQPLKIFYPPAEQL
What is the function of this protein?
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites.  Specifically binds phosphatidylserine.  Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site.  This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation.  Probably acts upstream of the Ca(2+)-dependent membrane resealing process (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 72, Mitsugumin-53, Mg53.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma. Cytoplasmic vesicle membrane. Note=Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine.
Protein: RHGE_ASPOR
Sequence: MQSKTFSVLSSCLLLIATVQGQLSGSVGPSTSISDKKAVKTCNVLDYGATNDNKTDVGQPIMNAFEDCGSGGVIYIPEGDYLIQEWVSLRNGTAFAIQLDGVIYRNGTTTSQGYMFGISGGSDFELYSSTSKGAIQGSGYLYHMNGEFTAPRLLHISDVSHWSVHDIALVDAPMFHFVIDDASNGEVYNMAIRGGNSGGLDGIDVSGDNIWIHDVMVTNKDECVTVKTGSHNFQIENIYCNWSGGCAMDSLGSGTNVSNIVYRNIYTWNSNQMYMIKSNGGDGEVSNLLFENFIGHGNAYSLDLDSEWSSMDTVDGDDGESRPPIRVICPEAIPCTDITIEDVDLWTEEGDSETYVCKNAFGSGACLKSDSSSTATYATTTTVTSAPSGYSATTMAADLTSAFGTDASIPIPTIPTSFYPGATPYSALAGSS
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonase E, RGase E, RHG E.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DRC10_RAT
Sequence: MALNLLSIPPSYHGLIIQRIPLKTGLVPAEPLKTLAPSKSKLNTIEAKRIMSVLDEAINKVELITLMSYLESHPEALEDALPENFVEAIREHLDIGQALVEKASILQRKQKELEKGEEAEEDWDQERLLSIELHKTNLWPLTHQFRDSTKTILRLLINEPQLTRLLHTQAPGRSPGAQCLLTSLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSKRNQEIIDALQAELAEVLKNKEAEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDYRASQARQAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMNEKQEEYEDLETIHKEEKLQLEELKERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAMWKGYLVRSMLRSRKKKRVKSKGKDKGKGKEKPKEEKGKEKKAKGKGKGKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
What are the official names of this protein?
Dynein regulatory complex protein 10, IQ domain-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the DRC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: RS9_STRPF
Sequence: MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CG033_HUMAN
Sequence: MQVEVQSLSLEECPWRLPGPQCECEALLPSGARRRIDLRLSGRAVAVWVHVRGGPGQFNLSYATGRHKKPNPHQNMNRGMEFIAPVSAPTKSGAPWHFLSQGPTDAQRAVRIRPGTRMGLSSDPVVGTLSSSYLDLLTLSYKPGRTVTSSYLNVRGHEVRKLQNSVEATRISRTDSS
What are the official names of this protein?
Uncharacterized protein C7orf33.
Protein: UTP11_CHATD
Sequence: MSSLRHAIQRRAHKERAQPLERQRLGILEKKKDYRLRARDYKKKQAVLKSLRQKAAERNEDEFYFGMMSRKGPGSALTRGKGFTGTVDGDRGNKALSVETVRLLKTQDLGYVRTMRNIAAKELKELEERYVLAGGADQPVEEFNSDEDEEESGSKQAKPKKIVFFEGVEERQQALEKQKADEEMKDYDEEEDGYDFDDEEEMTEKEKEERRKQLVLEKLARKVKAARKKLKALADAEYELELQQAKMAKTATSGGFTKSGRRIKVRERKR
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the UTP11 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PHC2_DANRE
Sequence: MEKEQEQGSVASSASVTIPSTTSVSTSTSAGTLSNSSSRQQTVPQISVYGGITDRQTVQVIQQALNRQPSTVAAQYLQQMYAAQQQHLMLQTAALQQQHLSLAAVQQASIVAGRQSCSQHGSTSQQTVASQTTINLATSPAARHLISRAQSGSSVPVCIGQQAVLLGNSSTPTLTASQAQMYLRAQMAQQTNLVQVARSLGRAVPLSSQLIFTPTASVTAIQPEAPAPSINTPPTSGQVQNLALRSQQGALTSTLSQSQLQSLSVKQSVASVTGQSVARLKGLGAEPSPQGTAAKASPAETSSETTAKNDKTSDLTTSVCPSVTSVAGHPFISTAYTQIQTHQLLQQHKQQFVIQQQPQILQRGQAQLLEAAAIHPHTVQAVAIQSALPAQPQQCPIPLLPKVPVTCQQATIFHSTTVSQQALAQNGQAHILTHTKAPPLQLTAVKCQIHPVQIQQGVASQNVPDKDTPVLLEPQLLSIPIQEPTRTELRQSDKESQVKENTQGSVNVKAGVGSPPAMTSGSGNNAPTVTGSAPQNGESKPPPQAVVKPQILTHVIEGFVIQEGAEPFPVERPSLLIENLKQKQHHAYSDLQKHNADSEMEDLSLQELNNQPEPVRTCEFCGNVDFAFNFKRSKRFCSTVCAKRYNVGCTKRMGLFPGKSSPEDTKKPKASDESPKNCSTETRKRNPSIQTTTGASLLSPHPSHPSHGESSQCSDMSSYEEPISPLSNSSFGAPIEHEESFDHSRELTPLLTQHFLASDPTKWNVEDVYEFICSLPGCHEIAEEFRSQEIDGQALMLLKEDHLMSTMNIKLGPALKIFARISMLKDS
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Polyhomeotic-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTCC_STAAC
Sequence: MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGIKHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEGINLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVMITDNIAEAVENTDAIYTDVWVSMGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLHCLPAFHDTNTLYGQEIYEKYGLAEMEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATLGS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_NEIMB
Sequence: MPTINQLVRKGRQKPVYVNKVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQARSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CDC26_PONAB
Sequence: MLRRKPTRLELKLDDIEEFENIRKDLETRKKQKEDVEVVGGSDGEGAIGLSSDPKSREQMIIDRIGYKPQPKPNNRSSQFGSLEF
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit CDC26, Cell division cycle protein 26 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_STRA1
Sequence: MGGDYVLSILIDKPGGITVEDTAQLTDVVSPLLDTIQPDPFPEQYMLEVSSPGLERPLKTAEALSNAVGSYINVSLYKSIDKVKIFEGDLLSFDGETLTIDYMDKTRHKTVDIPYQTVAKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_RICPR
Sequence: MKYNLNQLFKNHRIKGLSTNSKTVKEDEVFFAIKGQNVDGNDFINDALNNGAVLVITENKNNTAIDKVIYVEDVHKALYEAIEIFYPKKPKNLISVTGTNGKSSVVSYIAQAYSLLKKKAAFIGTIGLEIFGSNNIINDVPSLTTFDYLSFRKVAHNLAEDSIEYLAFEASSHGLEQGRLGKTKVNIVSFTSFSQDHLDYHHTKENYLLAKLKLFTDHLLPSGIAILNSDIEEIEFVKDYLHNNNVKFITVGKKGDLQITKITCSLTGQNIDFIFNNIIYNLHTLIIGSFQASNLLIAALTLYYTGFKFDEIIEALAKVKPIKGRMERIDGTNIFVDYSHTPDSLEKALIELKNIKLHGSKLSVIFGCGGDRDKTKRALMGQIAAKLADNVIITDDNPRFEDPKLIRAEIIRGIGTATYTEIASRAEAIKYGINNLKQDDILLIAGKGHETYQIIGDKKLPFDDSEVVRKYLFEISYTRN
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_YERPG
Sequence: MRLNTLSPAEGAKHAPKRVGRGIGSGLGKTAGRGHKGQNSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAMITAEVRLSELALVEGDVIDLNTLKAANVVGIQMEFVKVILSGEVNRAVTLRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TAAR5_PANTR
Sequence: MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNLFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDPLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKNLAGAAKHDRKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
What is the function of this protein?
Olfactory receptor specific for trimethylamine, a trace amine.  Also activated at lower level by dimethylethylamine.  Trimethylamine is a bacterial metabolite found in some animal odors, and is a repulsive odor associated with bad breath and spoiled food.  This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity).
What are the official names of this protein?
Trace amine-associated receptor 5, TaR-5, Trace amine receptor 5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIHH_METTH
Sequence: MPYKVKDISLAPQGEKKIRWVQEHMPVLERIKSDFSEEKPFKGVTIGSCLHLEPKTINLGLTLQAGGAEVAMTGCNPLSTQDDATAAGAKMGLNMYGWRGETNEEYYENIHRVLDHEPEILIDDGADMIFLVHRERPELLDGIIGACEETTTGINRLRAMAADGALKFPVMAVNDAYTKYLFDNRYGTGQSTFDSIMGTTNMLIAGKTVVVCGYGWCGRGIAMRAEGLGASVIVTEVDPIRALEARMDGFRVMKVSDAVKEADILITATGNTDVVSESEFMNMKDGCVMANSGHFNVEINREALEELSRETGKVKEDIEVFIMPDGRKIYLLAEGRLVNLASERGQGHPAEIMDMSFAMQALSARHLLQEKPDPGVYRAPDEIDLMVARMKLDAMGIEIDELTEKQRLYLENWEEGT
What is the function of this protein?
Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  Can also catalyze the reverse reaction in vitro, i. e.  the synthesis of SIH from Hcy and inosine.
What are the official names of this protein?
S-inosyl-L-homocysteine hydrolase, SIHH.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_CHRSD
Sequence: MSDSSSSSENAPATPESPGRPPRGIKSYVLRAGRMTAAQSRGLEEVWPRLGLSVAEGRQSLEALFGRRAPCVVEVGFGMGQSLVEQAAANPETDFIGIEVHAPGVGKLLDEADKRGLTNLRVYRDDALEVLDKCLPESSLTGLQLFFPDPWPKKKHHKRRIVQPAFVELVRTRLAPHGYLHMATDWEAYAEHMVEVMEEAPGYRNTAPPESAPYVPRPEFRPLTKFESRGERLGHGVWDLIYARVE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RS17_CHLL3
Sequence: MASSSTEGQAAARGRKKSWTGKVVSDSMDKAIIVAVERRVQHPVYKKYFKKTTRLMAHDEKNEAGMGDLVKVVECRPLSKRKSCRLVEIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS6_CARHZ
Sequence: MLRQYEVMYILHPELDAEKTESIIERFKGMIEQEGGEVTKIDRWGKRRFAYEIKKLREGYYVVMNFKAKAETAQELDRLLRISDDVVRHIVIREDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: CLCN2_CAVPO
Sequence: MAASAAAAGEGMEPRALQYEQTLMYGRYTQELGAFAKEEAARIRLGGPEPWKGPPSPRVPPELLEYGQSRCAPCCICSVRCHKFLVSRVGEDWIFLVLLGLLMALVSWAMDYAIAVCLQAQQWMSQGLNTNILLQYLAWVTYPVVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFVAKVIGLTCALGSGMPLGKEGPFVHIASMCASLLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFSATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVHQGLVEEQEPPSTSQAWNPPRANVFLTLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDGSTYRIVPGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPYVALNCTFRDLRLALHRTKGRMLALVESSESMILLGSIERSQVVTLLGAQLSAARRRQHIQERRKAQMSPPSDQDGLPSPESSVHFQVNTEDSAFIPARGETHKPLKPALKRGPSNASKAGETSTGSMESAGIALRSLFCGSPPPEATSDLEKPESCERRKLKRVRISLANDADLEGEMSPEEILEWEEQQLNEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPHSCHGLPRDGSPSDSDDKCQ
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport (By similarity).  Involved in the regulation of aldosterone production.  The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity).
What are the official names of this protein?
Chloride channel protein 2, ClC-2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARNE_ECO45
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFAAVNKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSLRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECFA1_LACDB
Sequence: MSDNIISFDHVTFTYPDSPRPAVSDLSFAIERGSWTALIGHNGSGKSTVSKLINGLLAPDDLDKSSITVDGVKLGADTVWEVREKVGIVFQNPDNQFVGATVSDDVAFGLENRAVPRPEMLKIVAQAVADVGMADYADSEPSNLSGGQKQRVAIAGILAVKPQVIILDESTSMLDPEGKEQILDLVRKIKEDNNLTVISITHDLEEAAGADQVLVLDDGQLLDQGKPEEIFPKVEMLKRIGLDIPFVYRLKQLLKERGIVLPDEIDDDEKLVQSLWQLNSKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL35_BORBR
Sequence: MPKMKTKKSAAKRFKVRGSGSIKRGQAFKRHILTKKTTKNKRQLRGSAAVHETNVASVKAMMPFA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.