PharMolix/UniProtQA huggingface dataset:
Protein: RIBB_VIBHA
Sequence: MSSTSLLDEFGTPVQRVERAIEALKNGLGVLLMDDEDRENEGDLIFSAQHLTEAQMALMIREGSGIVCLCLTEERANWLDLPPMVKDNCSKNQTAFTVSIEAKEGVTTGVSAKDRVTTVKTATYFDAQPEDLARPGHVFPLVAKTNGVLARRGHTEGTIDLMYLANLVPSGILCELTNPDGTMAKLPETIEFARRHGMPVLTIEDIVDYRTGIDLRNEYKSGLVREVSWS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, LUXH protein.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: HFQ_LEGPC
Sequence: MSKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAISTVVPSRMVKIPAEESSGEEEGTVAD
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: TEKT5_BOVIN
Sequence: MEFLGTTQTATYCGPKKPCGGSVLPSVASGPTVQECYQPYYLPGYRYLNAWRPSLFYKVANAQTCLDEGATCRSALRPPTILPAVRSALFCRYSPQDWDQSNRLQLCGAEASRLWAGRMTGDSMRLMQDKDQLTRQMQEGTCRNLGQRLSDIGFWKSELNYELERLLNENHSLDAIKRRLECAAEELRCPLQVALECLYQREKRIGIDLVHDNVEKNLIREVDMIKCCQEQMRKLAQRIDIQMRENRDAQHALERDLEDKNSAEFIDEKCLNLRNTSDCISFFHGVEKIDGTISVPETWAKFSNDNIRHSQNMRANSIRLREEAQNLFDVLADQLWRQFTNTNLAFNARIAEETDVKNKLQTQLAKTLQEIFQTENTIMLLERSIMAKECPLKVAQTRLECRTRRPNVELCRDSPQFKLVNEVFTIDDTLQTLKLRLRETRDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMAMRKTFPSTPCMGICP
What is the function of this protein?
May be a structural component of the sperm flagellum.
What are the official names of this protein?
Tektin-5.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Appears to be associated with flagellar accessory structures and not the axoneme.
Protein: DNAA_CHLAA
Sequence: MNLTQIWKATLSALQTQTSRHDYEALLRPATLLSLDNGAAFIGVSSPGQKEGLENRLLMPLRNALARVVGYPVQVQVLIANLNSRTEPSPSLTLSNGSRLMSDPEPVVAETPAPALTPGNGTGERVVQLDLASAMRSGMLNPRYTFSSFIVGSSNRLAHAACLAVADNPGQAYNPLFLYGGVGLGKTHLLHAIGNRVLDRDPEINVLYVSSEKFTNDLINAIRRQQTEEFRMRYRNIDVLLIDDIQFIAGKDATQEEFFHTFNTLHSAAKHIVISSDRPPKAILTLEERLRSRFEWGLIVDVQPPDLETRTAILRAKAEQMSVHVPDEVIDFLAHKIQSNIRELEGSLNRVAAYAELNRAPITIETATAALADLLGNQRRRRISAEAILQIVSEHYGIEVEQLRARNRSRHVVVPRQVAMYLLREETESSLVDIGNLLGGRDHTTVMYGCEKIAEEINSDSRLRSEVMAIRERIQMLRG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SET2_CANGA
Sequence: MSDISLAESIELNSSVPKDDQVFDDEIPDAEVQSEPSEEPPKLKRRLYLEEEDKTDEALSTFVNLEDCLYSNKHVGNCNSNDFMECDCYEDFQNGKNHACGEDSDCINRLTLIECVNDLCGTCGNDCANQRFQKKEYANIAVFKTKMKGYGVRAESDIEINDFIYEYKGEVIEEEEFRDRLVDYDQKKFRHFYFMMLQSGEFIDATIKGSLARFCNHSCNPNAYVNKWVVAGKLRMGIFAKRKILKGEEITFDYNVDRYGAAAQKCYCEEPNCIGFLGGKTQTDAASLLPQNVAEALGVKASEEKKWIKLKKAEGQKIEKSEAENINIEFLESITINPCNTATDVQKVMSVLLQIENKTVAQKLLQRLYLSSNEELLHHVIKLHGYTCFTKLLQLFALEEDELKKILYFLERLPKTTKNGIISSHIDFQVKSVCKNHSSLSSIGDSLIEKWKAYEEYKRITKLDINNSTKTKLQDIRRIKLPPGWEIVFENGRPMYYNAEKKTKLLYPPTGASKTFASQKSSSPIPKFKNKRDQNNGIKRKLTDEEYEERKRKRIELEQENIKKAKEEELQRLKAKFNQEREQKQILENIIAEANRKKEEERQNQLKIEKEKKDKKESKKQLSQISKMEHKWTKFFASVVPNILKKYESDKKIDHDNMKQCARDIVKILAAKEMKKDSSKEPEATVSKEKRHKIKQFVHGYMEKFLEKLDKKKQRH
What is the function of this protein?
Histone methyltransferase that trimethylates histone H3 'Lys-36' forming H3K36me3.  Involved in transcription elongation as well as in transcription repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-36 specific, SET domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS21_POLSJ
Sequence: MTTIRVKDNEPFDVALRRFKRTIEKLGLLTDLRAREFYEKPTAERKRKKAAAVKRNYKRIRAMQLPKKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS20_BRASO
Sequence: MANTTSAKKATRKIARRTIINKSRRTQMRGAVRSVEDAIKKGDREAALKAMANAEPQLMRAAQRNIIHKNNASRKVSRLVHQIAKLAAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FRMA_ECOHS
Sequence: MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
What is the function of this protein?
Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent.
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_NEIMB
Sequence: MADMKRLKHLMFSPFIDNNPIALQVLGICSALAVTTKLQTAIVMGISVALVTGFSSFFISLVRNYIPNSIRIIVQMAIIASLVTLVDQLLQAFAYELSKQLSVFVGLIITNCIVMGRAEAFAMKEPPLESLIDGIGNGAGYGIMLLVVATVRELIGSGKLLGYTVFQTVQDGGWYQTNGLFLLAPSAFFIIGFLIWGLRTWKPEQAEE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL30E_METHJ
Sequence: MDFNTSLRRAIKTGKVILGQNETKDSIEKGSAKLVVVAANCPAEFSGYLSGKDGVKTYTYEGSGVQLGRACGKPFIVSALAIEESGDSDILTLSR
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: PDXT_MYCBP
Sequence: MSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLDLDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQVDSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEMTGDRRIHQLFVDIVTSAA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: MRAY_SHESA
Sequence: MLVYLAEYLTRFHTGFNVFSYVTFRAILGLLTALMFSLWWGPKLIERLQLMQIGQVVRNDGPESHFSKRGTPTMGGLMILGAIFISVLLWGDLGSRYVWVMLFVLGSFGMIGFIDDYRKVVRKDTKGLIARWKYILQSLAALIIAFFLYTTASNPGETQLVVPFFKDVMPQLGAVFIVLAYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHAQFANYLHIPHLPGSGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGAIAVLVRQEILLVIMGGVFVMETVSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1066_BACVZ
Sequence: MIMTTTETIAGKQITEVKGLVTSSIVQSRHIGKDLLAGLKSVVGGELKSYTEMLEDSKKAVKERLIREAEQLGANAIVGLRFELTAGQNTSELIGYGTAVTAESIKKNKPL
What are the official names of this protein?
UPF0145 protein RBAM_010660.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: COXX_SYNJA
Sequence: MTGIPFGHHQSLAQVLRSYSQLVKPKIIALLLMTTAGAMWMAGNTDPFKFGVTLLGGGMAAAAANVINMVYDADIDRMMERTRHRPLPSGRIRARHALRFAGILAVMSFGLLACFTNLLAASLAMAGILVYVGVYTHWLKRSSPQNIVIGGAAGAIPPLVGWAAATGELSWAAWVMFALIFLWTPPHFWALAILKREDYARAGVPMLPVVAGERPTAAQILLYALLLVPVSLLLVYPLHVLGSFYLSAATLLGSLLIWKAVQLLQEPHSRERATSLFTFANLYLLLLCGAMGLDRWSLTHTLWDQALASLQGVYASLGALANHLGAMGSLG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP2AB_MOUSE
Sequence: MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
What is the function of this protein?
Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events.  PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, PP2A-beta.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles (By similarity).
Protein: MFRP_HUMAN
Sequence: MKDFSDVILCMEATESSKTEFCNPAFEPESGPPCPPPVFPEDASYSVPAPWHGRRPRGLRPDCRFSWLCVLLLSSLLLLLLGLLVAIILAQLQAAPPSGASHSPLPAGGLTTTTTTPTITTSQAAGTPKGQQESGVSPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENPCGPSELSCQAGGCKGVQWMCDMWRDCTDGSDDNCSGPLFPPPELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVEVLSGYKSLTSLPCYQHFRRLLCGLLVPRCTPLGSVLPPCRSVCQEAEHQCQSGLALLGTPWPFNCNRLPEAADLEACAQP
What is the function of this protein?
May play a role in eye development.
What are the official names of this protein?
Membrane frizzled-related protein, Membrane-type frizzled-related protein.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein.
Protein: ACDH_PECAS
Sequence: MTNLNKKVRVGIIGSGNIGTDLLIKTMRSESLTCTIFAGRNFNSAGMKRANELGVHISDRGIQAILDDPSICDVVFDATSAQAHIEHWRELEPLDKTVIDMTPAKVGGFCIPAINAEEILASGNRNINMVTCGGQSSIPIANAISSVHPEFEYIEVASSIASRSAGPATRANLDEYIDTTEKALKQFTGAQRTKAILILNPAVPPIDMQTTIYAKIDRPNIAAIDAAVREMVERLKRYVPGYQLVLPPTLDGNRVVTTVKVMGNGDYLPQYAGNLDIINCAAIAVTEMISSLRYGK
What is the function of this protein?
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A.  Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RS15_THET8
Sequence: MPITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PUR5_ALKMQ
Sequence: MAMPKLTYEEAGVNVQEGQRAVNLMKESVKSTFTKGVLGDIGGFGGLFALDPREMEKPILVAGTDGVGTKLKLAFMMNRHDTIGEDCVAMCVNDILCQGAKPLFFLDYIATGKLKAEVVAEIVQGIANGCKKAGCALIGGETAEMPGFYQKGEYDVAGFTVGMVEEKNLITGKEISQGDIMIGISSSGVHSNGFSLVRKLFFEDKQYSVDQYVDGLGETLGEALLRPTKIYVKPILEVLQQEKIKGMVHVTGGGFYENIPRILPEGIDANVHLDTWQAPPIFQFIQQEGQIEQDEMFSTFNMGIGMIVVVERSAGEKVVQLLQELGEEASIIGEMVRGSKQVVLCQK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAR_ORITS
Sequence: MKKIMLIASAMSALSLPFSASAIELEDEVGLECGPYAKVGVVGGMITGAESTRLDSTDSEGKKHLSLTTGLPFGGTLAAGMTIAPGFRAELGVMYLRNISAEVEVGKGEVDSKGEIKADSGGGTDAPIRKPFKLTPPQPTMMPISIADRDFGIDIPNIPQAQAQAAQPPLNDQKRAAARIAWLKNCAGIDYMVKDPNNPGHMMVNPVLLNIPQGNPNPVGQPPQRANQPANFAIHNHEQWRSLVVGLAALSNANKPSASPVKVLSDKIIQIYSDIKPFADIAGINVPDTGLPNSASIEQIQSKIQELGDTLEELRDSFDGYINNAFVNQIHLNFVMPPQAQQQQGQGQQQQAQATAQEAVAAAAVRLLNGSDQIAQLYKDLVKLQRHAGIRKAMEKLAAQQEEDAKNQGKGDCKQQQGASEKSKEGKVKETEFDLSMVVGQVKLYADLVTTESFSIYGGVGAGLAYTYGKIDNKDVKGYTGMVASGALGVAINAAEGVCVDLEAGYMHSFSKVEDKYQVNAFIASACVRYNF
What is the function of this protein?
May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain.  It is the major outer membrane protein.
What are the official names of this protein?
56 kDa type-specific antigen, TSA, 56 kDa scrub typhus antigen, STA56, TSR56.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOK_COXBU
Sequence: MIPLGYFLIIGAILFGLGFAGIIINRKNLIVLLMCIELMLLAVNTNFIAFSQYLGARAGEIFVFFILTVAAAESAIGLAILVLFYRRRGSINVDDMNILKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPB_BORA1
Sequence: MSMNVAWLSPGAAYADVWEAMKAFTASRGPATPDEIWLCEHAPVYTLGQAGLPQHVLNPADIAVVRSDRGGQVTYHGPGQIVVYCLFDLRRAGMYVRDYVALLEETAIAVLGRAGIVAQRKPGAPGVYVEQPGQTLAKIAALGIKIRKGCAYHGLSLNVAMDLTPFHGINPCGYEGLQTTDMASCGLSCSVHEVGQALADELVRRLSAYQGSLSSGE
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RHIEC
Sequence: MGSLSMWHWLIVLVIVLLLFGRGKIPELMGDVAKGIKSFKKGMTDEDAPETAKTVDHKADETK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL28_HYPNA
Sequence: MSRECELTGTKPMVGNIVSHSQIKTKRRYLPNLVQVTLRSEALDQNFRMRIAAKALRTVDKLGGLDAFLAKAKEEGLSTKALKIKRDIAKKAVA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FYN_PIG
Sequence: MGCVQCKDKEATKLTEERDGSLNQSSGFRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQGLTVFGGVSSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance.  Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain.  Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.  Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin).  Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT.  Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage.  Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6.  Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein.  Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation.  Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation.  Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts.  CSK maintains LCK and FYN in an inactive form.  Promotes CD28-induced phosphorylation of VAV1.  In mast cells, phosphorylates CLNK after activation of immunoglobulin epsilon receptor signaling (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Present and active in lipid rafts. Palmitoylation is crucial for proper trafficking (By similarity).
Protein: TPMT_VIBA3
Sequence: MNNPEFWHNKWAANQIGFHLEDVNPLLIKFWEKTEPNYEKSVFVPLCGKSEDLIWLATKHEEVQGVELSQIAVRAFFAEHLYTPTVTQISGQHELYQFDELNIYTGDYFTAPIQPVDTIYDRASLVALPAEIRAQYVERLKQLLKPGGKILLVTLDYDQSEMAGPPFSVPKLEIDQLFAGYKITLLNQDIADDEHPKIAKKGLSRFSEEVYLIESEA
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER_PSALA
Sequence: MVSGVSRNAARTSSGCIVALVSTDDDYTSQDVTTIPQAIRFPSSCLVTYSCVSCYLAIPSGKLHAASSFEHVLECTVAPVSEYVKSVFVGSSIECTGRSGSVTFALV
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What are the subcellular locations of this protein?
Hydrogenosome.
Protein: LIPL_BACCR
Sequence: MSNSRSILSQPEWRIVDQSSLGPTFHALQSFAMDDTLCTSIGNGKSAATMRSWVHHNTIVLGIQDSRLPHLEEGISFLKQHNFNVIVRNSGGLAVVLDEGVLNVSLLFQETEKGIDIDLGYDTMWHLIKEMLKDYDVTIEAKEIVGSYCPGSYDLSIRDQKFAGISQRRIRGGVAVQIYLCATGSGSERAALVRDFYNLAIQGEETRFTYPEIVPSTMASLSELLGETITVQDLMMRLLKTLQQFAPKLTPSQLTIDEIPLYETNLQRIIDRNNKALGLEK
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: OLE12_CORAV
Sequence: MADRPQQLQVHPQRGHGHYEGGIKNQRGGGPSAVKVMAVLAALPVGGTLLALAGLTLAGSVIGLLVTSPLFIIFSPVLVPAAIVVGLAVASFLSSGALGLTGLSSLSWVLNYLRCASQSLPREMDQAKRRMQDMAAFVGQKTREVGQEIQSRAQEGRRT
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin Cor a 12.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.