PharMolix/UniProtQA huggingface dataset:
Protein: METK_CHLCH
Sequence: MSQKRYFFTSESVSEGHPDKVADQISDAVLDDFLRQDSTSRVACETFVTTGQVIVGGEVTTKGIVDVQTIARKVITDIGYTKGEYMFEANSCGILSALHSQSPDINRGVDRKEEIADEFDRVGAGDQGMMFGYACTETPELMPAAIQFAQQLVKKLAEIRKEGKMMTYLRPDAKSQVTLEYENDIAKRVDAIVISTQHDPEPAGISEAEWQEIIKKDVIENVIKVLIPANMIDENTKLHINPTGRFEIGGPHGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAARHVAKNIVAAGLAEKCTVQVSYAIGVARPVSIYINTHDTAKHGLSDNQIQEKAEAIFDLRPAAIIKHFGLDKPNGWCYQQTAAYGHFGRDIFPWEKTDKVAELKAAFKLA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_BACMK
Sequence: MLNPSIDSLLTKIDSKYTLVTVAAKRAREMQIADNCVIEKPVSYKCVGKALEEIDLEVLKYVPSDDTIID
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PDXT_STRR6
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILAIVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: NPIIB_ASPFN
Sequence: MAFINSAAEDEVQFEGIKRRLRSSGITKEAVTSLGAGETLEDEFDIASTSDLASGGPVSIRSHGFVPIVVDGKITGYIPYKSNDLTVNVDGGKAAKVTKALSQLTRRTEVTDCKGDAESSLTTALSNAAKLANQAAEAAESGDESKFEEYFKTTDQQTRTTVAERLRAVAKEAGSTSGGSTTYHCSDPYGYCEPNVLAYTLPSKNEIANCDIYYSELPPLAQKCHAQDQATTTLHEFTHAPGVYQPGTEDLGYGYDAATQLSAQDALNNADSYALYANAIELKC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog AFLA_119780, Deuterolysin AFLA_119780.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_SINMW
Sequence: MAKKEVAKKTVTVEQIGSPIRRPAVQRQTLVGLGLNKMHRVRTLEDTPAVRGMIRAVQHLVRVVDEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PNP_SHEAM
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADGAVMASMGDTTVLVTVVGKKEADPGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPDDFTNEVQVIITVVSVDPQIEPDIVSMIGTSAALAISGIPFNGPLGAARVGYVNGEYVLNPGAAELAGSELDLVVAGTQSAVLMVESEAKSLPEEVMLGAVVYGHDQQQVVINAINEFAAEAGKPRWNWTAPVKNEALVAQIKELAEEGLTAAYQIMAKQERYEAVGEVKKATIAKLQEANPDVNVREAADLLGSLEKNVVRGRIIAGMPRIDGREPDMIRALSVMAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGTRDGVTALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSARPDISDFAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASNNGDATREAIRRIEEITSEVEVGRLYTGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLQLNQEVTVKVMEVDRQGRVRLSIKEAQVKEPAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS1_STRP1
Sequence: MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEKMKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRRIIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKRLADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIAHGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRALKMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATLKALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVINIVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDITIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 1, Formyltetrahydrofolate synthetase 1, FHS 1, FTHFS 1.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RSMH_ACIC5
Sequence: MERERHVPVLLQDAIRYLNVRRGGTYADATLGLAGHSSAIARLLGPGGTLIAFDRDPEAMELAKSRLDALRAELGSEMPKVILHSTEFSEAEDLIEPGSLDGLLADFGVSSLQFDEAHRGFSFQADGPLDMRMNPRVGLTAAQVVNQFGEKELADLIYEFGEERRSRRIARAIVRARPVSTTAQLARVVSAAAPAMKSERIHPATRTFQALRIYVNQELGQIEALLKVAPKLLRKGGRLVVISFHSLEDRIAKDALREGGQQGIYEVLTRKPLTAGEEETDRNPRARSAKLRAAEKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR_RAT
Sequence: MVRPLNCIVAVSQNMGIGKNGDLPWPLLRNEFKYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLDDALKLIEQPELASKVDMVWVVGGSSVYQEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSEIQEEKGIKYKFEVYEKKD
What is the function of this protein?
Key enzyme in folate metabolism.  Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.  Binds its own mRNA (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: COX3_VANPO
Sequence: MLNYMERSKHQQFPFHLVNPSPWPIVVSFSLLSLALSLGLTMHGYIGEMYLVNLALLVVLGSGVLWFRDIIAEATYLGDHTAAVRKGINIGFLLFVLSEVLIFSALFWSYFHSAMSPDVTLGACWPPVGITAVQPTELPLLNTIILLASGATVTYSHHALIQGNRKNSLSGLLITTWLIIIFVICQYIEYTNATFTISDGVYGSVFFAGTGLHFLHMVMLAIMLAVCYWRLRNYHLTNSHHVGYETTIIYLHVLDVIWLFLYIVFYWWGV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III, Cytochrome oxidase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRP_ECOLC
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: RBL_SYNS3
Sequence: MSKKYDAGVKEYRDTYWTPDYVPLDTDLLACFKCTGQEGVPKEEVAAAVAAESSTGTWSTVWSELLTDLDFYKGRCYRIEDVPGDKESFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKCCAGPPNGIAVERDRMNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDFTKDDENINSQPFQRWQNRFEFVAEAIKLAEQETGERKGHYLNVTANTPEEMYERAEFAKELNQPIIMHDFITGGFTANTGLSKWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDQLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALVAIFGDDSVLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAGKHSPELAIALETWKEIKFEFDTVDKLDVQ
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: LHX6_MOUSE
Sequence: MAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPTRLPSALSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADLDGPLSSRGEKVILFQY
What is the function of this protein?
Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development.  Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
What are the official names of this protein?
LIM/homeobox protein Lhx6, LIM homeobox protein 6, LIM/homeobox protein Lhx6.1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXB_HAES1
Sequence: MIDKKNITIGIVAGEVSGDILGAGLIRALKIQYPQARFIGIAGKNMLAEGCKTLVDMEEIAVMGLVEVIKYLPRLLKIRRLVIDTMLAEKPDIFIGIDAPDFNLDIELKLKKQGIKTLHYVSPSVWAWRQKRIVKIAQATNLVLAFLPFEKAFYDRFNVPCRFVGHTMADIIDLQPDRQDACFQLNLEPKHRYVAILVGSREAEVQFLTPPFLQTAQLIKQRFPDVQFLVPLVNEKRRKQFEQIKAQIAPHLEVVFLDGQARQAMIVAEASLLASGTASLECMLCKSPMVVGYKMKPFTYFLAKRLVKTKYISLPNLLADDMLVPEMIQEDCTAEKLAEKLSVYLEQTESGIKNRQHLIQQFTQLHQLIRCNADKQAAQAVIDLLNDEV
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: C3H53_ARATH
Sequence: MSHRDHGADGWESADFPITCESCFGDNPYMRMTRADYDKECKICSRPFTAFRWRPGRNARFKKTEICQTCSKLKNVCQVCLLDLGFGLPVQVRDSALNINSHYSVPMSHVNREYFADEHDPKTRAGLDYESSFGKMQPNDTILKLQRRTPSYEKNRPKICSFYTIGQCKRGAECSFRHEMPETGELSHQNIRDRYYSVNDPVAMKLLRKAGEMGTLEPPEDESIKTLYVGGLNSRIFEQDIHDHFYAYGEMESIRVMAEDGKYDQSGSNQQQQGSIAHTGLISQQQNQHSQMQQYYMQPPPPNEYSHYPSMDTQRMGAAFSTQESDGSSTSENNRAYSSYSYPMPPHQPYPTPPPYIDIYIYI
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 53, AtC3H53.
Protein: QUEF_SULNB
Sequence: MKYGEKEIQEFDINAEENFWPNEHEKNYTINIELPEFMCLCPRSGYPDFAIMKLSYVPDKKVIELKALKLYINSFMYRHISHENSANEIFDALYSQLEPKSMKLIADFNPRGNVHTVIEIDSETF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_BORPE
Sequence: MSKPALRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQKALKGVIMELEDCAFPLLHEVTAHSDPRTAFKDADVALLVGARPRGPGMERKDLLSVNAQIFTAQGRALNDVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALSQLSAKSGKRVADIEKLIVWGNHSPTMYPDFRFATVGGQGLTQLINDDAWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGIPSDGSYGIPEGIIYGFPVVTENGEYKMIKDLEIDAFSRERLDFTLKELLEERDGVKDLLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: DNAK_XANC5
Sequence: MGKIIGIDLGTTNSCVSIMDGGKARVIENSEGDRTTPSIVAYTKDGEVLVGASAKRQAVTNPKNTFYAVKRLIGRKFTDGEVQKDISHVPYGILAHDNGDAWVQTSDAKRMAPQEISARVLEKMKKTAEDFLGEKVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKNGGDRKIAVYDLGGGTFDVSIIEIAEVDGEKQFEVLATNGDTFLGGEDFDNRVIEYLVDEFNKDQGIDLRKDPLALQRLKDAAERAKIELSSSQQTEVNLPYVTADASGPKHLNIKLTRAKLEALVEDLVKKSIEPCRTALNDAGLRASDINEVILVGGQTRMPKVQQAVADFFGKEPRKDVNPDEAVAVGAAIQGGVLAGDVKDVLLLDVTPLSLGIETMGGVFTKIIEKNTTIPTKASQTFSTAEDNQSAVTVHVLQGEREQARFNKSLAKFDLSGIEPAPRGMPQVEVSFDIDANGILHVSAKDKKTNKEQKVEIKAGSGLSDEEIQRMVADAEANREEDKKFQELVQARNQADGLIHATRTAITEHGSKVGGDVIGKVEAALSDLETAMKGDDKAQIEARTKTLEEAGQSLYAAAAAAEQGGNADAASGNAQASKAADDVVDAEFTEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AROC_FRASN
Sequence: MVRWLTAGESHGPALVATVEGLPAGIRVSSTDIGAELARRRLGHGRGARMKFEQDEIELLGGLRHGVSLGGPVSVVVRNTEWPKWERVMAPDPIDPAELEGLGRNAPLTRPRPGHADLAGMQKYGFDDARPVLERASARETAARVALGTVARALLRQAYGIEVVSHVVAIGAVEVPPGTPPPTSLAVVDADPVRCADPASSALMVAEIDAAHRDADTLGGIVEVLAYGCPPGLGSYVHGDRRLDARLAGELMGIQAIKGVEFGDGFRTARRRGSVAHDEIEPLEGPGRRVRRASDRAGGVEGGMTTGEPLRVRAAMKPISSLSKPLATIDVATGDPAVAIAQRSDVCAVPAAGVVAEAMVALVLAGAALEKFGGDSVEETRRNYEGYLKSLAVR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: BMP6_MOUSE
Sequence: MPGLGRRAQWLCWWWGLLCSCGPPPLRPPLPVAAAAAGGQLLGAGGSPVRAEQPPPQSSSSGFLYRRLKTHEKREMQKEILSVLGLPHRPRPLHGLQQPQPPVLPPQQQQQQQQQQTAREEPPPGRLKSAPLFMLDLYNALSNDDEEDGASEGVGQEPGSHGGASSSQLRQPSPGAAHSLNRKSLLAPGPGGGASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPHQRHHKEFKFNLSQIPEGEAVTAAEFRVYKDCVVGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLEFDITATSNLWVVTPQHNMGLQLSVVTRDGLHVNPRAAGLVGRDGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVSRGSGSSDYNGSELKTACKKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation (By similarity).  Also plays an important role in the regulation of hepcidin/HAMP expression and iron metabolism by acting as a ligand for hemojuvelin/HJV (PubMed:19252486).  Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2B.  In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target.  Can also signal through non-canonical pathway such as TAZ-Hippo signaling cascade to modulate VEGF signaling by regulating VEGFR2 expression (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VGR-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SIGK_MYCTO
Sequence: MTGPPRLSSDLDALLRRVAGHDQAAFAEFYDHTKSRVYGLVMRVLRDTGYSEETTQEIYLEVWRNASEFDSAKGSALAWLLTMAHRRAVDRVRCEQAGNQREVRYGAANVDPASDVVADLAIAGDERRRVTECLKALTDTQRQCIELAYYGGLTYVEVSRRLAANLSTIKSRMRDALRSLRNCLDVS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigK, ECF sigma factor SigK, Alternative RNA polymerase sigma factor SigK, RNA polymerase sigma-K factor, Sigma-K factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: ANMK_BURP1
Sequence: MQTGHPADGVYFGLMSGTSMDGVDGVAVRFEAGKPPAVLSEAFVGFADTLRDALFALQQPGDDEIEREALAANALAARYAVCCHELLRTAGLSPDDVRALGVHGQTVRHRPERGYTRQLNNAALLAELTRIDVIADFRSRDVAAGGQGAPLVPAFHATVFGSPDETRVVCNLGGISNITILPAGGGPQGEGHARNDTVRGHDCGPANALIDAWVERHLKQPFDDGGRFAARGTVDETLLAALLDEPYFRQNAPKSTGRDLFNADWLDAKLAGFQHLAPENVQATLTALTAATVADEIARHAGDCRAVYVCGGGARNPVLLDALATALAARGLDAAVATTAALGVPPQQVESLAFAWLAYRFNARAPGNVSTVTGAAGERVLGALYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: U91B1_ARATH
Sequence: MAEPKPKLHVAVFPWLALGHMIPYLQLSKLIARKGHTVSFISTARNISRLPNISSDLSVNFVSLPLSQTVDHLPENAEATTDVPETHIAYLKKAFDGLSEAFTEFLEASKPNWIVYDILHHWVPPIAEKLGVRRAIFCTFNAASIIIIGGPASVMIQGHDPRKTAEDLIVPPPWVPFETNIVYRLFEAKRIMEYPTAGVTGVELNDNCRLGLAYVGSEVIVIRSCMELEPEWIQLLSKLQGKPVIPIGLLPATPMDDADDEGTWLDIREWLDRHQAKSVVYVALGTEVTISNEEIQGLAHGLELCRLPFFWTLRKRTRASMLLPDGFKERVKERGVIWTEWVPQTKILSHGSVGGFVTHCGWGSAVEGLSFGVPLIMFPCNLDQPLVARLLSGMNIGLEIPRNERDGLFTSASVAETIRHVVVEEEGKIYRNNAASQQKKIFGNKRLQDQYADGFIEFLENPIAGV
What are the official names of this protein?
UDP-glycosyltransferase 91B1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PSAD_SPIOL
Sequence: MAMATQATLFSPSSLSSAKPIDTRLTTSFKQPSAVTFASKPASRHHSIRAAAAAEGKAAAATETKEAPKGFTPPELDPNTPSPIFAGSTGGLLRKAQVEEFYVITWESPKEQIFEMPTGGAAIMREGPNLLKLARKEQCLALGTRLRSKYKIKYQFYRVFPSGEVQYLHPKDGVYPEKVNPGRQGVGLNMRSIGKNVSPIEVKFTGKQPYDL
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein.
What are the official names of this protein?
Photosystem I reaction center subunit II, chloroplastic, Photosystem I 20 kDa subunit, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
Protein: RPOC_CAUSK
Sequence: MNQEVLNIFNPVQAAPTFDQIRISLASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIWFLKSLPSRIAMMLDMPLKDIERVLYFEYYIVTEPGLTPLKQHQLLSEDDFMRAQDEYGDDSFTAEIGAEAIQNLLKAIDLDKEAERLREELAGTVSDMKQKKFSKRLKILEAFSESGNRPEWMVLTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHECGLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPQVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLSVAREGEPGEGKIFADLGEIEAAMDAGVVSLHAKIKSRFTEMDADGVVRRRVIDTTPGRMKIAALLPQHTAIGHRLIEKALTKKEIGNLIDVVYRHCGQKATVIFADQIMGLGFKEAAKAGISFGKDDIIIPKRKEAIVAETRTLAEEYEQQYADGLITKGEKYNKVVDAWAKATDRVADEMMAELQMKHKDENGREKEINAIYMMAHSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIVSNFKEGLTVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEEDCGTTRGITLRAVVEGGDVLVSLGARVLGRFSAEDIKDPATGEIVVPADTYLTENMADLIEAAAVQSVKVRSVLTCEAKIGVCGACYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGTAQVAEQSFFESSNDGTVRVTGATVVGTDGFLVVMSRNTAVSVLVDGKERENYKPPYGARLKIKDGDKVKRGQRLADWDPYTTPIITEVAGKIRAEDLVDGFSVREETDEATGIAQRVIADWRTSARASDLRPAMGVLAEDGSYVRLANGGEARYLMSVGAILSVGDGDMVKPGEVIARIPTEGAKTRDITGGLPRVAELFEARRPKDCAVIAEMDGRVEFGKDYKNKRRIKITPEVDADGNQGEPVEFLIPKGKHIAVHDGDFIARGEYIIDGNPDPHDILRILGVEALANFLVDEIQEVYRLQGVPINDKHIETIVRQMLQKVEILEPGDTGLIKGDHLDKPEFYVEQDRAVARGGRPATTQPVLLGITKASLQTKSFISAASFQETTRVLTEASVHGKTDTLEGLKENVIVGRLIPAGTGSYLRSLQRVAAKRDEQLAQQREDAMEPLPAVIAEEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.