PharMolix/UniProtQA huggingface dataset:
Protein: OR2H1_HUMAN
Sequence: MVNQSSPMGFLLLGFSEHPALERTLFVVVFTSYLLTLVGNTLIILLSVLYPRLHSPMYFFLSDLSFLDLCFTTSCVPQMLVNLWGPKKTISFLGCSVQLFIFLSLGTTECILLTVMAFDRYVAVCQPLHYATIIHPRLCWQLASVAWVMSLVQSIVQTPSTLHLPFCPHQQIDDFLCEVPSLIRLSCGDTSYNEIQLAVSSVIFVVVPLSLILASYGATAQAVLRINSATAWRKAFGTCSSHLTVVTLFYSSVIAVYLQPKNPYAQGRGKFFGLFYAVGTPSLNPLVYTLRNKEIKRALRRLLGKERDSRESWRAA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2H1, Hs6M1-16, OLFR42A-9004.14/9026.2, Olfactory receptor 2H6, Olfactory receptor 2H8, Olfactory receptor 6-2, OR6-2, Olfactory receptor OR6-32.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU3C_DAUCA
Sequence: MFLLYEYDIFWAFLIISSLIPILAFFVSGVLAPINKGPEKLSSYESGIEPMGNAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGISVFVEALIFVLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL23_BUCA5
Sequence: MISEERLLKILLSPHVSEKTSISMEKFNTVVLKVLNNATKYEIKYAVKKIFDVDVDSIKTLKVKGKKKRQSNRIIQRSHWKKAYIKVKKGCNLDFIGNTE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CALM_PHYIN
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEILEAFKVFDKDGNGFISAAELRHIMTNLGEKLTDEEVDEMIREADIDGDGQINYEEFVKMMMSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: MATK_MACCO
Sequence: MDKLQRDGKEDTSRQRRFLYPLLFQEDFYTIAYDHCSNRSSSFEPMGNSSSNDRFSFLTVKRSISRIRQQNGSIVPFVNCDQNKLVGHNKSFYSELVLGGLTAVSEVPFSIRSKHSLEGMNEWASFRSINSIFPLMEDKIPHSNFILDIRIPHLTHPEILVRTFRRWIQDAPFLHSLRSVLHEHRNLIISSNLDQLILIASKKNTRLSLFLWNYYAYECESLLVPLWKRFSHSRSLPYESFIERTPFYRKIEHIVIFYHKYLKKSLWFLKDPSIHYVKYRERSIIALRGTYLLVKKWRYHLTNFWQCHFHLWLQPYRIYIDELSNNCFSFLGYLLSVKMKTSVVRIKMLDDSFITDLITKEFDPIAPTTLLIGSLVKEKFCDISGHPFSRLAWTGLTDDDILDRFDRIWRNIFHYHSGSSKKDGLYRMKYILRLPCAKTLACKHKSAIRAVRERFGSELFTKSFPKERESIFLSFSKTRSQRERIWYSDIIQRNPFVNS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KIBRA_HUMAN
Sequence: MPRPELPLPEGWEEARDFDGKVYYIDHTNRTTSWIDPRDRYTKPLTFADCISDELPLGWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERGFQTLKKIDKKMSDAQGSYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRTDRGSHSDLWSSSSSLESSSFPLPKQYLDVSSQTDISGSFGINSNNQLAEKVRLRLRYEEAKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQLEMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSSSMQSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDPFEQLDSELQSKVEFLLLEGATGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSPLMADPLLAGDAFLNSLEFEDPELSATLCELSLGNSAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAAVSDESVAGDSGVYEASVQRLGASEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILIIQLSNLSALLQQQDQKVNIRVAVLPCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGAQISLAEVCRSGERSTRWYNLLSYKYLKKQSRELKPVGVMAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEETSENEAVAEEEEEEVEEEEGEEDVFTEKASPDMDGYPALKVDKETNTETPAPSPTVVRPKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLERRSVRMKRPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEQLEQAKSHGEKELPQWLREDERFRLLLRMLEKRQMDRAEHKGELQTDKMMRAAAKDVHRLRGQSCKEPPEVQSFREKMAFFTRPRMNIPALSADDV
What is the function of this protein?
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis.  Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway.  Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation.  Regulates collagen-stimulated activation of the ERK/MAPK cascade.  Modulates directional migration of podocytes.  Acts as a substrate for PRKCZ.  Plays a role in cognition and memory performance.
What are the official names of this protein?
Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, KIBRA, WW domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the WWC family. KIBRA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Cell projection, ruffle membrane. Note=Colocalizes with PRKCZ in the perinuclear region.
Protein: RL3_SOLM1
Sequence: MAATLGILGRKLGMTRVFGDDGSIIPVTVIQAGPCPVTQVKNLEKDGYNAMQIGFDEIPERKVNKPEKGHLDKAARGYFRVLKEIRLDGPVPFEQGMDVTVDIFAPGEIVKVTGTSIGKGFAGVMKRWNFAGLKKTHGTEKAHRSGGSIGNNTEPGKVMKGKKMAGHMGARTVTVPSITVVDVRPEMNLILVKGQIPGPRNGVVVVRKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ENO_STRP4
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: IF2_MYCGA
Sequence: MNKKPTRNKKPVDQRSKINIKSYLKEVQVGVKDGVFIYTDPLSIDQFAKKVNQPVAKIIKHFFSKGINTINLNTILSLEQIGELCLDLGLDFKIEKSVTSENLLDNIEFKDKKEDLVKRPPIVTVMGHVDHGKTSLLDAIRSTNVTSNEAGGITQHIGAYQVKKNDELITFIDTPGHEAFTEMRARGANLTDIVVLVVAGDDGIKPQTEEAIDHAKNANVPIIVFVNKMDKSGANFDRVIQQISKYDLSPEEYGGDTIFVQGSAIKKEGINELLDAILTLAEINEYKANPNADPYGIVIESKLEPGLGPQATVIIKRGTLKVGDYICIGAAYGKVRIMQDENGNNLTEATPSRPVKISGLDAIPQAGEKFLGLATEKEVKELSDSYKLKQQKQKHLSLQESHEKRTRINTNGIKCVDLIIKSDVQGSLEAIKYAISNINIEGVTTNIIRASTGVISETDIKLAQASNSTVISFNLGVSKQIRDLANSDNVQILSYEIIYKMVEDLEKIMKGELDPVYEESVIGQAVVRVLWKHSKIGTIAGSYVTSGKVVKNALCRVLRDDVIIYKSKIASLKSKTTFVDKVEHNKECGIVVENYNDIKEDDIIEVYEIVKKRVY
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LBD5_ARATH
Sequence: MEPLGNRRPCSVCITKNRNCPRFCEYAEYFPYELQSQYESANELFGTPNIITMMQHAPEEKKQMLATSIIMEGNAWTEDPISGGFGMIQKLMWKIMLHKAYLRELQEKIKEEKEKKPASSLY
What are the official names of this protein?
LOB domain-containing protein 5, ASYMMETRIC LEAVES 2-like protein 33, AS2-like protein 33.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: TRMR_BACSU
Sequence: MTDRYEQINDYIEALLKPRPDNVKRLEAYAEEHHVPIMEKAGMEVLLQILSVKQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEFQLDDRIHVFYGDALELADAVHVTAPYDVIFIDAAKGQYQNFFHLYEPMLSPDGVIITDNVLFKGLVAEDYSKIEPKRRRRLVAKIDEYNHWLMNHPDYQTAIIPVGDGLAISKKKR
What is the function of this protein?
Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA 5-hydroxyuridine methyltransferase, ho5U methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: XERDL_STRT2
Sequence: MTISSFQKQLTTQITNFLARKTISDSSKQAYAYDLKQFVNCLPGRVDQTSLKLYENQLKEWKPSVQKRKRSAVNQFLLYLYQKGELEEFFKLSETAPLPSQQEELEIFDLSSLYEGQEGPGKLACLFILELGLLPSEILELKWEDIDLDFGVVTVAKGSTKRVLRLDGALKELLFGIKNDNSQGLILSKAFTRQWLYKQIQSYVGGCGLSGVTAQALRQQYILRQIEKGTGAFELARLLGLKSPVTLEKYYKT
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA2_MAGMM
Sequence: MSGVSELLLPSPVPQGVEGVLHGLHGRWRGRAAHRRRLMQLAEQAERRCMALLGLPETQLQQQLLEIQSRFRRRLLTDDETLLAGVALVGELAWRAVQKRPYRVQFMGALAMHRGWLAEMATGEGKTLTVAVAAVLAGWSGRACHVISANDYLTERDAQQMTPLYEACGVTVASGGGALSPEERQLCYKADVVYVTAKTLLADYLRDQLATRQGAGRAQQGFAQWLTGGAQQPSAMMLGRGLHTVIIDEADSVLIDEAVTPLILAAPQKIPGMHGAVMWAAEVAERLHEEEDYTADRRTRQIQLLEGANQLMAAMAWRLDAVWRSEVRRQELVRHALSVRHFIRVGQHYLVQEDKVVLLDDATGRMTPERSLTAGLHQAIEAYEGVPLTDPNASMGQMSFQTFFRRFHRFCGTTGTARESTRELWRIYRLAVLPIPTHRPRQTVVHPTRVYATLEDKWQAVAAEVAQVHASGRPVLVGVRSVSSSEQLAAVLVEKGLSAQVLNARNHAEEAAIVSRAGQSGHVTIATNMAGRGTDIGLEEQTRSLGGLHVIIAECNSSARIDRQLAGRCGRQGDPGSVVTLLCLEEDVLRQQLSPALLGIARSLPRWGWAAGVLAGLVHYAQRRSEAQAYGQRRAVMQGDEWLNNALPF
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MRAZ_TROWT
Sequence: MFLGTHPVRLDDKNRFVLPAKFRGMLDSVVLTRGQERCLYLFDRSEFERISDGIRNTALSQKKVRDYLRIFLSGAAAQLPDRQHRIVIANHLRAYADLKKEVTVIGAGKHVEIWDSEAWSSYLEEQEAAFSEIAEEVIPGLI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PURL_OCEIH
Sequence: MQLTHDIQPEKIEKDRLYLDMGLSDEEFQRIKQILGRHPNFTETGIFSVMWSEHCSYKTSKPLLKKFPTDGPHVLQGPGEGAGVIDIGDEQAVVFKIESHNHPSAVEPYQGAATGVGGIIRDVFSMGARPIASLNSLRFGPLTNNRTKYLFSEVVAGIAGYGNCVGVPTVGGEVQFDESYEDNPLVNAMCVGLINHKDVQKGIAAGIGNTILYAGPPTGRDGIHGATFASDDLAEDSNKDRPAVQVGDPFMEKLLIEACLEVIQSDALVGIQDMGAAGLTSSASEMASKAGTGLEMNLDLVPQREQGMTAYEMMLSESQERMLLCVQAGREQEIIDIFEKYGLKSVPVGKVIEEKVFRIKHLDEVVADIPVDSLADDAPVYNMPSKEAAYYRAFQQMDIATPAIEDYANTLKQLLQQPTIANKEWVYDQYDSMVQTNTVVTPGSDAAVVRIKGTEKALAMTTDCNSRYIYLDPETGGKIAVAEAARNIVCSGAKPLGLTDGLNFGNPTNPEIFWQMEKSVEGMSAACDALHTPVISGNVSLYNQSKGKSIYPTPIVGMVGLHESTQHITPSYFQEKEDVIYCIGEAKAEFGGSELQHLYSGKYEGKAPHIDLDVEAERQEKLLSAIKEGIISSAHDISEGGLAIALAESLFNGQGLGAEINVVGDATVELFSESQSRFLVSVNKKHANAFESHFPEAAKLGKVTDQGQLTISISDKTIIHERVEELENLWKGAIPCLLKSKA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_ERWT9
Sequence: MLSKQRVVITSGEPAGIGPDLVVQLAQQDWPVELVVCADPELLRDRAAVLRLPLTLREYQPGTDAQPQQAGSLTVLPAHLAQPVNAGELCVDNSHYVLETLARACDGCLSGEFAALITGPVHKGAINDAGIPFSGHTEFFAERARCERVVMMLATEELRVALATTHLPLKDVAASITRTTLHEVITILYQDLQSKFGRAEPHIFVCGLNPHAGEGGHMGREEIDVIIPALDELRQQGMKLTGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAGSGQADAGSFKTALNLAITMIKSSNE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN_SCHCO
Sequence: SLQAATEWLKANNQRGFLGEMGAGSNAD
What are the official names of this protein?
Endoglucanase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: BROX_DANRE
Sequence: MTHWFHRNPLKATAPVSFNLYGVASSPAANKICNDLRTARARLLDMFTDATCSPDTLKKSSDEYFALLQGFILPLDGTTQENKLRFIQNFKWTDTLQGNIASAQQDAVFELVSMAFNVALWYTKFASRLAGKENITEEEAKDVHKSLKIAAGIFKTLKETHIPRLITPAEKGRDLEPRVIDTYIVQSQAEAQEVTIARAIELKHNASLIAALAFETANFYQKADHTLNTLDPECSSKWKKYLQLKQHFYMAYAHCYHGQTLLAGDKCGEAIRSLQEAEKCYSRAEVLCKEYRQMKGPGSTAKPSEQLFFKKLGAVIKNTLEKCQRENGFIYFHKVPAEAPALELKASYGLAEPTAFELPPLSAQCTPEVYATFDLTRGHKDDKAKAKPEEEIKPVKEPDLKPQKDTGCVVC
What are the official names of this protein?
BRO1 domain-containing protein BROX, BRO1 domain- and CAAX motif-containing protein.
What is the protein family that this protein belongs to?
Belongs to the BROX family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: PANK4_PONAB
Sequence: MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKDTERDHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETGDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDTLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFSKEDMAKSLLHMISNDIGQLACLHARPHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSTSPELGPAQRARSGTFDLLEMDRLERPLVNLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPCFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALREERLLLVQTGSSSPCLDLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEVPAE
What is the function of this protein?
Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway.  Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms.  Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein.  May play a role in the physiological regulation of CoA intracellular levels.
What are the official names of this protein?
4'-phosphopantetheine phosphatase, Inactive pantothenic acid kinase 4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the damage-control phosphatase family. Phosphopantetheine phosphatase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_HAHCH
Sequence: MLKIYSSLSQQKEEFKPIQAGKVGIYVCGMTVYDYCHLGHARVLVCFDIITRYLRAKGYDVNYVRNITDVDDKILNRARDNGESVDALTARFIDAMHEDERALGVLSPTSEPRATGHIDEIIAMIQRLMDKGYAYHASNGDVYYSVEQFADYGKLSKQKLDEIRAGARIEVDAEKRSPADFVLWKAAKPGELSWDSPWGEGRPGWHIECSAMSTRCLGDTFDIHGGGPDLKFPHHENEIAQSEAATGCKYVNYWMHAGAVRVNKEKMSKSLGNFFTIREILDKYPAEVVRYFLASSHYRSAIDYSDVALEEARSGLERLYNSIRELYGELGAVSMDEPLVGEYRERFHQAMDDDFNTSSAVAVLFDMAKAVNVAKKEDRTRALSLAKGMVDLAEVLGLLQADPESLMQGEGEEVGGLSVAEIEDFIAQRNAARANKDFAESDRIRDLLKEKGVLLNDSREGTSWQRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y249_METTH
Sequence: MIEMEILRNTVQKIAKHAIEAIDKVDEAELEMMISKIMDASSVFIVGTGRSELIGKAFAMRLMHLGFKVHVVGDVTTPAIRDEDCLIAISGSGETKTVTLAAETSRSVGATVVAVTATPESTLTGYSDVVICIPSKTKEPWKYYTSGVLRGEYDDLTPMGTLFEDSTHLFLDGLIAEFMSILGKREKDLKERHAIIE
What are the official names of this protein?
Uncharacterized protein MTH_249.
What is the protein family that this protein belongs to?
Belongs to the SIS family. PHI subfamily.
Protein: ISPH_CAMLR
Sequence: MEIELAKSYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEITRLWKNYNVKTLNDISELSTEQKAIIRTHGITKQDLEKLKQKDIEIFDATCPFVTKPQKICEQMSKEGYEVVIFGDENHPEVKGVRSYVSTKAYVVLDEKELFDIKLPSKIAVVSQTTKKIEKFMEIVNFLMLKVKEVRVFNTICDATFKNQEAINELAKKSDVMVIVGGKNSANTKQLFLIAKNYCEDSYLIENEKEIQKEWFSGKEKCGVSAGASTPDWVIDLVLEKIKEYTKIN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: URE2_PSYIN
Sequence: MIPGEIKTDAGDLQLNVGCEQLTVTVANSGDRPIQVGSHYHFYEVNPALKFEREKCRGYRLDITSGTAVRFEPGQQRQVTLIAYRGKRRVFGFRASIQGDL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C85A1_ARATH
Sequence: MGAMMVMMGLLLIIVSLCSALLRWNQMRYTKNGLPPGTMGWPIFGETTEFLKQGPNFMRNQRLRYGSFFKSHLLGCPTLISMDSEVNRYILKNESKGLVPGYPQSMLDILGTCNMAAVHGSSHRLMRGSLLSLISSTMMRDHILPKVDHFMRSYLDQWNELEVIDIQDKTKHMAFLSSLTQIAGNLRKPFVEEFKTAFFKLVVGTLSVPIDLPGTNYRCGIQARNNIDRLLRELMQERRDSGETFTDMLGYLMKKEGNRYPLTDEEIRDQVVTILYSGYETVSTTSMMALKYLHDHPKALQELRAEHLAFRERKRQDEPLGLEDVKSMKFTRAVIYETSRLATIVNGVLRKTTRDLEINGYLIPKGWRIYVYTREINYDANLYEDPLIFNPWRWMKKSLESQNSCFVFGGGTRLCPGKELGIVEISSFLHYFVTRYRWEEIGGDELMVFPRVFAPKGFHLRISPY
What is the function of this protein?
Catalyzes the C6-oxidation step in brassinosteroids biosynthesis (PubMed:11402205, PubMed:12529536).  Converts 6-deoxocastasterone (6-deoxoCS) to castasterone (CS).  May also convert 6-deoxoteasterone (6-deoxoTE) to teasterone (TE), 3-dehydro-6-deoxoteasterone (6-deoxo3DT, 6-deoxo-3-DHT) to 3-dehydroteasterone (3DT, 3-DHT), and 6-deoxotyphasterol (6-deoxoTY) to typhasterol (TY) (PubMed:11402205, PubMed:12529536).  Required for the initiation of female gametogenesis (megagametogenesis) (PubMed:21364326).
What are the official names of this protein?
Cytochrome P450 85A1, AtCYP85A1, 3-dehydroteasterone synthase, Brassinosteroid-6-oxidase 1, BR6ox 1, C6-oxidase 1, Castasterone synthase, Teasterone synthase, Typhasterol synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: WZYE_ECOHS
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTHS3_RUBXD
Sequence: MLTNLEIARGAKLLPIEEVGRSMGLREERHLEPYGRHVAKVDLCAIEDLSERPKAKYILVSAITPTPLGEGKTTTTVGLGQAFSHIGKRATIAIRQASMGPAFGIKGGAAGGGYSQVVPMERLNLHLTGDLHAVTEAHNMLAAMIDNHLYHGNGLGIEPHSISWRRVMDVNDRSLRNIVIGLGARTDGVPRQSGFDITAASEVMAILALASSLEDLRERLGRIVIGHNREGNPVSAEDVRGAGAMAVILKEAIKPNLMQTLEGTPALVHAGPFGNIATGNSSVVADLIGIRTADYLITEAGFGADMGAERFFNIKCRISGLEPDAAVVVATVRALKAHSGRYQIKAGAPLPEELLEENPQDVLAGAENLKKQIENIKLHGVPAVVAINAFPTDHPSEHKAIEEAAKEVGARCAVCRHFTEGGKGAVELARALEETIEENERERRRGGGGSFRFLYPLEMPLKQKIETIAREVYGAEGVEYDAEALRALEGFERAGFGRLPVCLAKTHLSLSSDPALKGAPRGWKLSVREVRASVGAGFIYPICGQMRTMPGLSAHPAAERIDLDGEGNVVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 3, Formyltetrahydrofolate synthetase 3, FHS 3, FTHFS 3.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.