PharMolix/UniProtQA huggingface dataset:
Protein: BRID5_HUMAN
Sequence: MEPASCCAERPKPGPTGVKTKPSCGGWRAVSLLLLLLLLVLAAVGVVAGGLLGSAQGPPKPRLQTLRMTLPSPHMPRPNQTILVDVARNAATITVTPPQSNHSWAVLFDGQSGCICYRPEEHQVCFLRLMEDSDRETLRLLVDTSKVQEAWVPSQDTHHTQELLAVQGSLEVDPAQAGALVQRLCMRTPIYWARRAEGESGPLWGKARPSGWFEELGAEPLEIHGTLATGPRRQRLIYLCIDICFPSNICVSVCFYYLPD
What are the official names of this protein?
BRICHOS domain-containing protein 5.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNMG_STAAR
Sequence: MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PESC_SCLS1
Sequence: MGRIKKKGTAGQAKNFITRTQAVRKLQISLPDFRKLCIWKGIYPREPRNKKKASKSSTHSTTFYYTKDIQWLLHEKIVDAFREQKALEKKISKALGRGDAHDAARLERNASRPEKTGKTKYNLDHIIRERYPTFIDALRDLDDCLSMLFLFANLPSTSTVPAKMIARCEKLCLEFEHYLIVSNSLRKSFLSIKGIYYQATIQGQDILWLVPYRFNQRVTGDVDFRIMGTFVEFYQTLLGFVNFRLYTSVGLVYPPKFDKARDDQDAGLGAFSLEGNGIGAIEQPKQITNGDASKPDPKLQAEIDKLMLQLNAPEKEAEETSKTSPDGEEEEQATETIDKFEPAAPGGDILMQPSYSATDPSTLFSKFTFFLSRETPRQSLEFILRAFGCKRIGWDAVLGEGAFTHNESDPSITHQVVDRPPMQVQPEEEEEIKEDNQTAQRLRPGARIPGRIYIQPQWIWDCINDEELKRPDLYAPGAQLPPHLSPFVKKVRGQYDPSAPLQDQEREDEELEMDSGSEDEADVSDDETAVKKQDPLTAMDVDETAEGMDVAGSDDESDEAPEKADESFGGFSEAEESEDEGETAALRRQRELEAELSGVALQEKEVDPRVKAKTDAKKKAAKKAKEEDEELERSKMMMSRKKRKILEKMVYSNKKKDAEAEALRAKRRKIEKSGKAAPRE
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ATPD_MESH7
Sequence: MYLYKKNYYGYAESLLDISISENNVEKYINDCFFILSIIQNNQVLILLFKSHFVGKQEKFNIIDKIFSAKIEKILVNFLKVIAKNNLFLHYKQILLKYIKLANSHLSQTWGEIETAFPISSVMTSSFESILSKKLGKKVHLRHKINSKLISGIRIIVDNQIFENSLFSELKLLKQNLKKHLITKNDL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRC_EDWI9
Sequence: MTVMQHTLKIRRPDDWHLHLRDDAMLHSVLPYTSRHFSRAVVMPNLVPPITSVEQCIAYRQRILDAVPQGHAFTPLMTCYLTDALSVDTLMHGQREGVFTAAKLYPANATTNSACGVTSIPGLYPLFEAMQQSGMPLLIHGEVTQADIDIFDREARFIEQVMLPLRRDFPELRIVFEHITTREAAQFVAEGDRYLAATITPQHLMFNRNHMLVGGIHPHLYCLPILKRSVHQQALRKAATSGQTCFFLGTDSAPHLRGRKESACGCAGVFNAPTALQAYATVFEEEQALQHLEAFCSLNGPAFYGLPANEAYIELAQEPASVVDSIASGDETLTPFLAGETLRWSVRA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: DAPB_THEMA
Sequence: MKYGIVGYSGRMGQEIQKVFSEKGHELVLKVDVNGVEELDSPDVVIDFSSPEALPKTVDLCKKYRAGLVLGTTALKEEHLQMLRELSKEVPVVQAYNFSIGINVLKRFLSELVKVLEDWDVEIVETHHRFKKDAPSGTAILLESALGKSVPIHSLRVGGVPGDHVVVFGNIGETIEIKHRAISRTVFAIGALKAAEFLVGKDPGMYSFEEVIFGGE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable).  Uses NADPH as a reductant with much more efficiency than NADH.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_LENCU
Sequence: MKESQVYLERARSRQQHFLYSLIFREYIYGLAYSHNLNRSLFVENVGYDNKYSLLIVKRLITRMYQQNHLIISANDSNKNSFWGYNNNYYSQIISEGFSIVVEIPFFLQLSSSLEEAEIIKYYKNFRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDAPFFHLLRLFLCNWNSFITTKKKKSISTFSKINPRFFLFLYNFYVCEYESIFVFLRNQSSHLPLKSFRVFFERIFFYAKREHLVKLFAKDFLYTLTLTFFKDPNIHYVRYQGKCILASKNAPFLMDKWKHYFIHLWQCFFDVWSQPRTININPLSEHSFKLLGYFSNVRLNRSVVRSQMLQNTFLIEIVIKKIDIIVPILPLIRSLAKAKFCNVLGQPISKPVWADSSDFDIIDRFLRISRNLSHYYKGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEEFLQEFFTEEEEILSLIFPRDSSTLERLSRNRIWYLDILFSNDLVHDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NANT_YERPG
Sequence: MSISVGPSREDKPLSGGAKPPRWYKQLTPAQWKAFVAAWIGYALDGFDFVLITLVLTDIKQEFGLTLIQATSLISAAFISRWFGGLVLGAMGDRYGRKLAMITSIVLFSFGTLACGLAPGYTTLFIARLIIGIGMAGEYGSSSTYVMESWPKNMRNKASGFLISGFSIGAVLAAQAYSYVVPAFGWRMLFYIGLLPIIFALWLRKNLPEAEDWEKAQSKQKKGKQVTDRNMVDILYRSHLSYLNIGLTIFAAVSLYLCFTGMVSTLLVVVLGILCAAIFIYFMVQTSGDRWPTGVMLMVVVFCAFLYSWPIQALLPTYLKMDLGYDPHTVGNILFFSGFGAAVGCCVGGFLGDWLGTRKAYVTSLLISQLLIIPLFAIQGSSILFLGGLLFLQQMLGQGIAGLLPKLLGGYFDTEQRAAGLGFTYNVGALGGALAPILGASIAQHLSLGTALGSLSFSLTFVVILLIGFDMPSRVQRWVRPSGLRMVDAIDGKPFSGAITAQHARVVTQK
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF1_CERS5
Sequence: MKKLSILAALAASPAMAATGPFFSLSNTNFIVTLAFLIFMGILVYAKVPGRILGMLDRRAVQIRSELEEARALREEARTILASYDRKQKEVQEQAARIVASARDEAQAAAEQAKADLKASIARRLAAAEDQIASAEAGAVRAIREQAISVAVAAASDVLARQMTPAATSASIDESIKEVEARFH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GREA_LEGPA
Sequence: MSKHPMTVEGAEALKAELHRLKFVDRPRIVEAIATARAHGDLKENAEYHAAREQQSFNEGRIQELEAKLSHAQIIDISKLPNNGKVIFGSTVTICHVATGSELTYKIVGEDEADIKLNKISYSSPIARALIGKELDDAVTVETPGGMVEYEIIQVQYIVE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: EPTA_SALTY
Sequence: MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNSLRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLACVFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLASVLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMLKGDRKNLTILIVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTTSCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINVLWNDNDGGCKGACDRVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNRYPPQFKKFTPTCDTNEIQNCSQEQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSLVYLSDHGESLGENGVYLHGLPYSIAPDTQKHVPMLIWLSKDYQQRYQVDQACLQKRASTLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE
What is the function of this protein?
Catalyzes the addition of a phosphoethanolamine moiety to the lipid A.  The phosphoethanolamine modification is required for resistance to polymyxin.
What are the official names of this protein?
Phosphoethanolamine transferase EptA, Polymyxin resistance protein PmrC.
What is the protein family that this protein belongs to?
Belongs to the phosphoethanolamine transferase family. EptA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSP3_HORSE
Sequence: AGSYYSYRRRRCSPRRLYRLRRRRYRSSRRRRRRPCRRRRHRRVCRRVRRRRRCCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm histone P2b, Protamine 2b, ST2b.
What is the protein family that this protein belongs to?
Belongs to the protamine P2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: COP1_CONPU
Sequence: MKLLAPVLWAMAALGVTWLVAVDSKESCTKHSNGCSTPLRLPCQEYFRPACDIHDNCYHCGTIFGISRKECDDAFLKDMNTLCKKLGSNSATCPARGKREVTSHRATSIAHSRLWKTALDQKSFLNRKARQAILLTPNSCLYWANNFYMAVHVFGARSYSRTTDPKDCQGLKHCLPNH
What is the function of this protein?
Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Conodipine-P1, Cdpi-P1, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2, PLA2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group IX subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HDOX_BACC3
Sequence: MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSPAFKAAHSHQGGMPDYILDNKISYYDVKVVRMPMAAAQ
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDF15_MACFA
Sequence: MPGQELKTLNGSQMLLVLLVLLWPPHGGAVSLAEASRASFPGPSDLHSEDSRFRELRKRYEDLLTRLRANQSWEDSNTDLIQAPEVRILTPEVRLGSGGHLHLRISRAVLPEGLPEACRIHRALFRLSPTASRSRDVTRPLRRQLRLARPQAPALHLRLSPPPSQSDQLLVKSSSSRPQLALHLRPRASRGRRRARARNGDRCPLGPGRCCRLHTVHASLEDLGWADWVLSPREVQVTMCIGACPSQFREANMHAQIKMNLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCV
What is the function of this protein?
Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.  Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem.  It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28846097).  On hepatocytes, inhibits growth hormone signaling (By similarity).
What are the official names of this protein?
Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_HELPJ
Sequence: MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGSAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLVEINHYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWGMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNIVLTGIVILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MLRC_SPHSX
Sequence: MLDRRTLMGGILSMAGSKATGAALPGRRLRVFVATLGTETNSFSPLPTGLDAFRATMLWRPGEHPDFATEATGPLWAARERAREGRYEVIEGTCAFAMPGGPVSAQAYQLLRDEILDQLRRAMPVDIVAFGLHGAMLAFGEDECEADLLERARAIVGPDVALGAELDLHAHLSQRLVRAADVLVAFKYYPHIDYVERARDLLDLLERIRAGEIMPTSSLFNCQMVAGLATQSSPMKELVADLFEFERRGEVLSGSLIQGFRAGDVARMGSKVLIYTNNDQPAAASIAQDFGRRYQAMASIMKGNGPERSFAADIELAKAATAYPVILVDSSDNPGGGASGDNMALARAMLDNDLVPSCIGPIWDPLAVQLGFEAGLGADFSLRVGGKVGEASGLPLDVRGKITGLAENVTQNLQGSRPPLGRVVCISTAGLDIIVSEIRDQCYGPDMFRALGVEPANKRYVAVKSSEQWRIGFGDMGRSVIYVASSQQSSIRHYHKRSRPMWPFEPV
What is the function of this protein?
Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) (PubMed:11769251, PubMed:8899999).  Cleaves both linear MC and the tetrapeptide degradation product of MC (PubMed:11769251).  Cleaves the Adda-Glu peptide bond of linear MC heptapeptides (PubMed:22591122).
What are the official names of this protein?
Microcystinase C, MlrC.
What is the protein family that this protein belongs to?
Belongs to the peptidase M81 family.
Protein: HDG5_ARATH
Sequence: MLTMGEGNVMTSNNRFASPPQQPSSSSPGTIQNPNFNFIPFNSYSSIIPKEEHGMMSMMMMMGDGTVEEMMENGSAGGSFGSGSEQAEDPKFGNESDVNELHDDEQPPPAKKKRYHRHTNRQIQEMEALFKENPHPDDKQRKRLSAELGLKPRQVKFWFQNRRTQMKAQQDRNENVMLRAENDNLKSENCHLQAELRCLSCPSCGGPTVLGDIPFNEIHIENCRLREELDRLCCIASRYTGRPMQSMPPSQPLINPSPMLPHHQPSLELDMSVYAGNFPEQSCTDMMMLPPQDTACFFPDQTANNNNNNNMLLADEEKVIAMEFAVSCVQELTKMCDTEEPLWIKKKSDKIGGEILCLNEEEYMRLFPWPMENQNNKGDFLREASKANAVVIMNSITLVDAFLNADKWSEMFCSIVARAKTVQIISSGVSGASGSLLLMFAELQVLSPLVPTREAYFLRYVEQNAETGNWAIVDFPIDSFHDQMQPMNTITHEYKRKPSGCIIQDMPNGYSQVKWVEHVEVDEKHVHETFAEYVKSGMAFGANRWLDVLQRQCERIASLMARNITDLGVISSAEARRNIMRLSQRLVKTFCVNISTAYGQSWTALSETTKDTVRITTRKMCEPGQPTGVVLCAVSTTWLPFSHHQVFDLIRDQHHQSLLEVLFNGNSPHEVAHIANGSHPGNCISLLRINVASNSWHNVELMLQESCIDNSGSLIVYSTVDVDSIQQAMNGEDSSNIPILPLGFSIVPVNPPEGISVNSHSPPSCLLTVGIQVLASNVPTAKPNLSTVTTINNHLCATVNQITSALSNTITPVIASSADVSNQEVS
What is the function of this protein?
Probable transcription factor (By similarity).  Involved, together with PDF2, in the regulation of flower organs development by promoting the expression of APETALA 3 (AP3) in the epidermis and internal cell layers of developing flowers (PubMed:23590515).
What are the official names of this protein?
Homeobox-leucine zipper protein HDG5, HD-ZIP protein HDG5, Homeodomain GLABRA 2-like protein 5, Homeodomain transcription factor HDG5, Protein HOMEODOMAIN GLABROUS 5.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_DEIGD
Sequence: MTRTGLSDTIAAIATAPGSAGVGIVRISGPDALGIADGAFRGRRRPSATRGGRFLFGQLVAGDGEVLDEGLCLVFRGPHSYTGEDVAELQTHGSPAVLARVLSRVLELGARPARPGEFTLRAYLAGRLDLAQAEAVLELVNAGTETARRQAALGLSGALGERVERIAAHVTRTLAALQAMLDYPEEGVPDEDRTVPLAAAEAELHALVGTARAGQVATRGARLALIGRPNAGKSSLLNALLGYERSIVTPIPGTTRDYLEAQLSLAGVPVTLVDTAGLRETGDEVEAAGVRQAVRLAESADLVLVLEDGSQPRDHLPAELPRETRMLRVRTKADLPAAWTDPGALDVSAVTGQGLSALRDAIHTALIGDAAQGEAWLTTERQADAARRALTHIQAARSLPDDLAGYELEEALRALADLTGRDVQDDVVDAVFRNFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH102_ARATH
Sequence: MASTFVCSLPNPFFAFPVKATTPSTANHTLLGSRRGCLRIKAISTKWEPTKVVPQADRVLVRLEDLPIKSSGGVLLPKAAVKFERYLTGEIISVGSEVGQQVGPGKRVLFSDVSAYEVDLGTDARHCFCKESDLLALVE
What is the function of this protein?
Functions as co-chaperone for protein folding in chloroplasts.
What are the official names of this protein?
10 kDa chaperonin 2, chloroplastic, Chloroplast chaperonin 10, Chl-Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GLYA_LACP3
Sequence: MDFMAQDPEVFGAIHNEEERQEHNIELIASENIVSPAVRAAQGSVLTNKYSEGYPGHRYYGGNQYIDVVENLAIDRAKKLFGAEFANVQPHSGSQANMATYRAFLEDGDKVLAMDLTDGGHLTHGSPVSFSGQEYHFYHYGLDPKTERLNYAKIREQAEQVQPRMIVAGASAYSREIDFKKFREIADHVGAFLMVDMAHIAGLVAAGLHMNPVPYADVVTTTTHKTLRGPRGGLILAKAQYGKAINSALFPGIQGGPLDHVVAAKAVALGEALQPSFKTYAQHILDNMQAMVSGFEEDPHLRLISGGSDNHMVLIDVTGYGVNGRQVQDLLDEVGITTNKNQIPGEQNGPFKTSGIRVGTAAITTRGFTADESKRVGELISAAIAQRDDQPALDQIHQEVLALTARHPLS
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_ECOLU
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COBT_CLOTE
Sequence: MVIIMKLLEETLRRIKPADEEVIKKAWSRMDSLSKPIGSLGKLEEIAVQISGITGKVKNEINKKMTVIMCSDNGICEEGVSACPQELTALLAENYVKEITGIGVLSKHVNADMCVVDIGIKSDVKDSRILNKKVAYGTKNMAKEPAMTREEAVKAIETGIELVDKFVKEGYDLFGTGEAGIGNTATSAAVISVLSQIDSDKIVGKGSGLTDEGFLNKKRAVKQAIEINKPNKEDVIDVIAKIGGFDIAGICGCFLGAAKNRVPIVIDGIISASAALCAYKMNANVKDFLISSHLSAEPGIEYVTGAIGLKPCLHMEMRLGEGSGCPLQFFMIESALCLMNNMATLAEASIVDSEFLVDIREK
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: AGD3_ARATH
Sequence: MHFTKLDDSPMFRKQLQSMEESAEILRERSLKFYKGCRKYTEGLGEAYDGDIAFASALETFGGGHNDPISVAFGGPVMTKFTIALREIGTYKEVLRSQVEHILNDRLLQFANMDLHEVKEARKRFDKASLTYDQAREKFLSLRKGTKSDVAAALEQELHTSRSMFEQARFNLVTALSNVEAKKRFEFLEAVSGTMDAHLRYFKQGYELLHQMEPYINQVLTYAQQSRERSNYEQAALNEKMQEYKRQVDRESRWGSNGSNGSPNGDGIQAIGRSSHKMIDAVMQSAARGKVQTIRQGYLSKRSSNLRGDWKRRFFVLDSRGMLYYYRKQCSKPSGSGSQLSGQRNSSELGSGLLSRWLSSNNHGHGGVHDEKSVARHTVNLLTSTIKVDADQSDLRFCFRIISPTKNYTLQAESALDQMDWIEKITGVIASLLSSQVPEQRLPGSPMGSGHHRSASESSSYESSEYDHPTTEEFVCERSFLGYNERPSRSFQPQRSIRKGEKPIDALRKVCGNDKCADCGAPEPDWASLNLGVLVCIECSGVHRNLGVHISKVRSLTLDVKVWEPSVISLFQALGNTFANTVWEELLHSRSAIHFDPGLTVSDKSRVMVTGKPSYADMISIKEKYIQAKYAEKLFVRRSRDSDFPQSAAQQMWDAVSGNDKKAVYRLIVNGDADVNYVYDQTSSSSLTLSRVILVPERPKREDVLLRLRNELLDRTGSSSNISPEGSGGSSLLHCACEKADLGMVELLLQYGANVNASDSSGQTPLHCCLLRGKVTIARLLLTRGADPEAMNREGKTALDIAAESNFTDPEVLALLSDTNGYNHRQC
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).  Involved in the spatial control of provascular differentiation.  Required for the formation of the normal pattern of continuous secondary veins.  Involved in auxin signaling but not in polar auxin transport or in auxin responses.  Required for PIN1 internalization in roots.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein AGD3, ARF GAP AGD3, Protein ARF-GAP DOMAIN 3, AtAGD3, Protein FORKED 2, Protein SCARFACE, Protein VASCULAR NETWORK 3.
Protein: PEPQ_SERP5
Sequence: METLASLYNDHLAELQKRAREVLTRNKLDALLIHSGELQRIFQDDRSYPFKVNAHFKAWVPVTSVPNCWLWVDGVNKPKLWFYSPVDYWHSVEPLPESFWTRSVELMPLANADDIAQQLPAQRERVGYIGYAQQRARDLGILAENVNPKAVLNYLDFHRSIKTGYELACMREAQKTAVMGHRAAHEAFLSGMSEFDINQAYLTATGHRDTDVPYDNIVALNEHASVLHYTTLDHQPPSEMLSFLLDAGAEYNGYAADLTRTYAGQSGSDFAQLIKDLNGEQLALMDTIKAGVRYTDYHVQMHQRVAKLLKSHKLVTGISEEAMVEQGLTTPFLPHGLGHPLGLQVHDSAGFMQDEQGTHLAAPSKYPYLRCTRMLQPGMVLTIEPGMYFIDSLLAPWRSGEFSQHFAWDRIDALKPYGGIRIEDNIVIHEKRIENMTRDLNLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: SPD1_SCHPO
Sequence: MHSSKRVMTTKTHVEQPESSMRPQLPESIQGSLMDVGMRVRKSISTGYKSKQTTFPAYNPPLYNTVSENIALKNTAFSYEPNGTKRPFEQAIPNYNWANPPQDFEEPEWLKPFDVVMEGTNERL
What is the function of this protein?
Regulates the ribonucleotide reductase activity through its mediation of the nuclear localization of suc22, the small subunit of the ribonucleotide reductase.  Delays the progression of the G1-S phase transition, thereby ensuring the G1 phase is complete.  Interacts with both p34 and the p34-p56 complex, although no direct inhibitory effect on the bound proteins has been demonstrated.  The action of p14 may happen coincidentally with the cdc10 function or may happen downstream of this.
What are the official names of this protein?
S-phase delaying protein 1, Protein p14.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.