PharMolix/UniProtQA huggingface dataset:
Protein: DAPF_CYAP4
Sequence: MSLQFTKYQGLGNDFILIDNRNEATPLLTPEQAVDICDRHFGVGADGVIFLLPATGETDYTMRIFNSDGSEPEMCGNGIRCLARFAADLEGHALTATPRYRIHTLAGTITPQVRSDGQVTVDMGQPRLLAGEIPTTLKPAAEKVIAQPLQVGGRSWSVTCVSMGNPHCITFVENVAAIDLHTLGPQFEHHPAFPQRINTEFIEVIRPDYLKMRVWERGAGMTLACGTGACAALVAAVLNDLSEPRATVELPGGPLEIEWSAPGQAVLMTGPAEQVFQGVL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_PYRCO
Sequence: MSWQAYVDDHLMCDIDGHHLTAAAILGHDGSVWAQSSTFPKFKPEEITAIMKDFDEPGSLAPTGLHLGGTKYMVIQGEGGAVIRGKKGSGGVTVKKTSQALVFGIYEEPLTPGQCNMIVERLGDYLIDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Allergen Pyr c 3.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ASSY_SACS2
Sequence: MKIVLAYSGGLDTTVSIRWLKETFKAEIITVTVDVGQKDDFKKIEERAYIAGASKHYTIDAVRQFANNYIAYAIKLNGLYEGVYPLSTALARPLIAEKVVEVAKKEGAEAVAHGSTSKGNDQVRFDLAVKALYPDVKIIAPARIWNMTREDEIKYAKEKGIPIKVESDKYSIDENLWGRSIEGDIISDPSLEVPEDAFEWTKQIYNKKEIVSIEFSNGVPTAVNGEKMELNKLVDFLNLKFGSHGFGRVEHIENRVVGFKSREVYEVPAALGLIYAHIDLEKTIYTPMELRFKRHIDQLWSDLVYQGLWFEPLRETLHKVADEMNKWISGEAKVEVSNGSFRIVGRESEYSPYSEKIASYNKGWYPSDEMARGFIEIWGMHSLIARRVRGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRA_ECOLI
Sequence: MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVVGADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYANSYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDNELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
What is the function of this protein?
Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism.  Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp).  Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE.  Binds asymmetrically to the two half-sites of its operator.
What are the official names of this protein?
Catabolite repressor/activator, Fructose repressor.
Protein: CDND_ACIS2
Sequence: MGSERIMTTQQQFLDLLSDIEPSTTTVNDCSSAHNTLRDALKVHNEFSKVHVHTFLSGSYKRNTAVRPTTIGGITQRPDVDIIALTNHTINDDPQIVLDAVHTALKDIGYTDLTVNRRSVNVKLKKVDMDVVPIISDGYGGYLIPDIHLEEWLVTNPPAHTEWTVEVNKNANGRFKPLVKLFKWWRRENLSDLKRPKGFILECLVAKHMNYYESNYEKLFVYLLETIRDSYGIYASLGIIPHLEDPGVAGNNVFSAVTADEFKTFFEKVEEQAAIARNALNETDDDKALALWRQVLGNRFPRSASHKSANSADMASSLIRSALGAGLTFPSTPVYPNKPGGFA
What is the function of this protein?
Cyclic trinucleotide synthase that catalyzes the synthesis of 2',3',3'-cyclic AMP-AMP-AMP (2',3',3'-c-tri-AMP or 2'3'3'-cAAA) as the major product, as well as another cyclic AMP(4) 2'-5'-linked minor product that acts as a second messenger for cell signal transduction.
What are the official names of this protein?
Cyclic AMP-AMP-AMP synthase, CD-NTase037.
What is the protein family that this protein belongs to?
Belongs to the CD-NTase family. D01 subfamily.
Protein: RL17_NOVAD
Sequence: MRHKLGQRKLGRTSSHRIALLRNMAAALIKHEQITTTLPKARELRPYLEKLITLGKKGGLSNRRLAHARLLDEAQEQKLFTTLAERYADRNGGYTRIIKAGYRASDAAPLAVIELVDRDTSAKGQDSGPVLTADEDEFEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UBP2_BOVIN
Sequence: MSQLSSTLKRYTESARFTDAPFTKSSYGTYTPSSYGTNLAASFLEKEKFGFKPSPPTSYLTRPRTYGPPSILDYDRGRPLLRPDVIGGGKRAESQTRGTERPSGSGLSGGSGFSYGVTTSSVSYLPVSARDQGVTLTQKKSNSQSDLARDFSSLQTSDSYRLDSGNLGRSPMLARTRKELCALQGLYQAASRSEYLADYLENYGRKASAPQVPTPTPPSRAPEVLSPTYRPSGRYSLWEKGKGQALVSSRSSSPGRDTMNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYLRDLSHSSRAHTALMEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVIARPKSNTENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPITKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTAFVNFPLRDLDLREFASENTNHAVYNLYAVSNHSGTTMGGHYTAYCRSPVTGEWHTFNDSSVSPMSSSQVRTSDAYLLFYELASPPSRM
What is the function of this protein?
Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1.  Possesses both ubiquitin-specific peptidase and isopeptidase activities.  Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity.  Has no deubiquitinase activity against p53/TP53.  Prevents MDM2-mediated degradation of MDM4.  Plays a role in the G1/S cell-cycle progression in normal and cancer cells.  Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.  Regulates the circadian clock by modulating its intrinsic circadian rhythm and its capacity to respond to external cues.  Associates with clock proteins and deubiquitinates core clock component PER1 but does not affect its overall stability.  Regulates the nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and BMAL1.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 2, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane.
Protein: MGSA_BURTA
Sequence: MSTPRIALIAHDAKKDEIVALAGAYRAALAQCRLVATGTTGGRIAQAHGLDVERKLSGPLGGDLQIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDDLARRLPVKA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: REHY_MEDTR
Sequence: MPGLTIGDTIPDLEVDTTQGKIKLHHFCSDSWTILFSHPGDFTPVCTTELGKMAQYASEFNKRGVMLLGMSCDDLESHKEWIKDIEAHTPGAKVNYPIISDPKREIIKQLNMVDPDEKDSNGNLPSRALHIVGPDKKIKLSFLYPAQTGRNMDEVLRVVESLQKASKYKIATPANWKPGEPVVISPDVTNDQAKEMFPQGFKTADLPSKKEYLRFTNV
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity).  Seems to contribute to the inhibition of germination during stress (By similarity).
What are the official names of this protein?
1-Cys peroxiredoxin, Rehydrin homolog, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ALLS_SPOFR
Sequence: MKTSAYNVYLGVVAAMLALLFVTINAAPMEADDETAENTLVAHPDGDMELSGPWDAINTAALRKLLLQLDAEDRMGGVTRSWPQAEPRGWGLRALDSRLARQWRADKRQVRFRQCYFNPISCFRK
What is the function of this protein?
Strongly inhibits juvenile hormone biosynthesis in vitro by the corpora allata from fifth-stadium larvae and adult females.
What are the official names of this protein?
Allatostatin, AS, Spofr-AS.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSM1_BOVIN
Sequence: MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLEEY
What is the function of this protein?
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (By similarity).  Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm1.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: RLMN_ENT38
Sequence: MSELVNTSEVATVAVPNKNGKINLLDLNRQQMREFFLEMGEKPFRADQVMKWMYHYCSDNFDDMTDINKVLRNKLKDVAEIRAPEVVEEQRSADGTIKWAIAVGDQRVETVYIPEEDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGTRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPVNKKYNIETFLAAVRRYLAKSNANQGRVTIEYVMLDHVNDETDHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMDYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGETIDVKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_FRATN
Sequence: MARLKDYYQKELVAKLKTELGLDNIMEVPAIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: BDBC2_BACAN
Sequence: MTIIRKYHIAIAWTIATSAMLISLIFSEWMKLPPCDLCWYQRMAMYPLVLILGIGMYRKDSNVSIYAFPFACIGLIISVYQITIQAFPTSEMKICSVGVSCTENYLNLFGFISIPMLSFVGFLAIIILLYINQIKRQKNK
What is the function of this protein?
Required for disulfide bond formation in some proteins.
What are the official names of this protein?
Probable disulfide formation protein C 2, Disulfide oxidoreductase C 2, Thiol-disulfide oxidoreductase C 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUK_MOUSE
Sequence: MALHLLLLFGACWVQVASPDSLQRTTMLPSTPHITAPSTSEAQNASPSVSVGSGTVDSKETISPWGQTTIPVSLTPLETTELSSLETSAGASMSTPVPEPTASQEVSSKTSALLPEPSNVASDPPVTAANPVTDGPAANPVTDGTAASTSISKGTSAPPTTVTTSSNETSGPSVATTVSSKTSGPPVTTATGSLGPSSEMHGLPATTATSSVESSSVARGTSVSSRKTSTTSTQDPITTRSPSQESSGMLLVPMLIALVVVLALVALLLLWRQRQKRRTGALTLSGGGKRNGVVDAWAGPARVPDEEATTTSGAGGNKGSEVLETEGSGQRPTLTTFFSRRKSRQGSLVLEELKPGSGPNLKGEEEPLVGSEDEAVETPTSDGPQAKDEAAPQSL
What is the function of this protein?
Protects cells from apoptotic signals, promoting cell survival.
What are the official names of this protein?
Leukosialin, B-cell differentiation antigen LP-3, Leukocyte sialoglycoprotein, Lymphocyte antigen 48, Ly-48, Sialophorin.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Cell projection, uropodium. Note=Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN). SUBCELLULAR LOCATION: [CD43 cytoplasmic tail]: Nucleus. Nucleus, PML body. Note=The sumoylated form localizes to the PML body.
Protein: RR15_CITSI
Sequence: MVKNAFISVRVQEKKEKNSGSVEFQVFRFTNTIRRLTSHLELHRKDYSSQRGLRKILEKRQRLLAYLSKKNRVRYKELISKLNIRESKNR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CD79A_MOUSE
Sequence: MPGGLEALRALPLLLFLSYACLGPGCQALRVEGGPPSLTVNLGEEARLTCENNGRNPNITWWFSLQSNITWPPVPLGPGQGTTGQLFFPEVNKNHRGLYWCQVIENNILKRSCGTYLRVRNPVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDCSMYEDISRGLQGTYQDVGNLHIGDAQLEKP
What is the function of this protein?
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation.  Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.  Stimulates SYK autophosphorylation and activation.  Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK.  Also interacts with and increases activity of some Src-family tyrosine kinases.  Represses BCR signaling during development of immature B-cells.
What are the official names of this protein?
B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein.
Protein: COPG_ARATH
Sequence: MAQPLVKKDDDHDDELEYSPFMGIEKGAVLQEARVFNDPQVDPRRCSQVITKLLYLLNQGESFTKVEATEVFFSVTKLFQSKDTGLRRMVYLIIKELSPSSDEVIIVTSSLMKDMNSKIDMYRANAIRVLCRIIDGTLLTQIERYLKQAIVDKNPVVSSAALVSGLHLLKTNPEIVKRWSNEVQEGIQSRSALVQFHALALLHQIRQNDRLAVSKLVGSLTRGSVRSPLAQCLLIRYTSQVIRDMANHGQSGERPFYEFLESCLRHKAEMVILEAARAITELDGVTSRELTPAITVLQLFLSSPRPVLRFAAVRTLNKVAMTHPMAVTNCNIDMESLISDQNRSIATLAITTLLKTGNESSVERLMKQITNFMSDIADEFKIVVVDAIRSLCVKFPLKYRSLMTFLSNILREEGGFEYKRAIVDSIVTIIRDIPDAKESGLLHLCEFIEDCEFTYLSTQILHFLGIEGPNTSDPSKYIRYIYNRVHLENATVRAAAVSTLAKFGFMVESLKPRITVLLKRCIYDSDDEVRDRATLYLSVLGGDGTVDTDKESKDFLFGSLEVPLVNMETSLKNYEPSEEAFDINSVPKEVKSQPLAEKKAQGKKPTGLGAPPAAPASGFDGYERLLSSIPEFAAFGKLFKSSLPVELTEAETEYAVNVVKHIFDSHVVFQYNCTNTIPEQLLERVNVIVDASEAEEFSEVTSKALNSLPYDSPGQAFVVFEKPAGVPAVGKFSNTLTFVVKEVDPSTGEAEDDGVEDEYQLEDLEVVAGDYMVKVGVSNFRNAWESMDEEDERVDEYGLGQRESLGEAVKAVMDLLGMQTCEGTETIPLNARSHTCLLSGVYIGNVKVLVRAQFGMDSSKDIAMKLTVRAEDVSVAEAIHEIVASG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit gamma, Gamma-coat protein, Gamma-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: OGT_METBF
Sequence: MYYDIIESPIGPILLAGNEKGLKHLDFLKGKKRIEIPADWIENKKFFREAARQLEAYFSGKLESFDLKLAPEGTDFQKSVWKALCEIPYGETRTYKEIAVSIGKPRAYRAVGLANNRNPIAIIIPCHRVIGSDGKLTGYASGLDIKEFLLKLEENNLR
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_ISOMA
Sequence: MAPINLNLILAFSLALLGVLIYRTHLMSTLLCLEGMMLSLFILMTLLISHFHMYSMSMAPLILLVFSACEAGVGLALLVKISTSHGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CTL1_ARATH
Sequence: MVTIRSGSIVILVLLAVSFLALVANGEDKTIKVKKVRGNKVCTQGWECSWWSKYCCNQTISDYFQVYQFEQLFSKRNTPIAHAVGFWDYQSFITAAALFEPLGFGTTGGKLMGQKEMAAFLGHVASKTSCGYGVATGGPLAWGLCYNREMSPMQSYCDESWKFKYPCSPGAEYYGRGALPIYWNFNYGAAGEALKADLLNHPEYIEQNATLAFQAAIWRWMTPIKRAQPSAHDIFVGNWKPTKNDTLSKRGPTFGSTMNVLYGEYTCGQGSIDPMNNIISHYLYFLDLMGIGREDAGPNDELSCAEQKPFNPSTVPSSSSS
What is the function of this protein?
No chitinase activity.  Essential for normal plant growth and development.  Regulates cell expansion extent and differentiation at least in roots and hypocotyls.  Prevents lignin accumulation in the pith.  May modulate ethylene-mediated regulation during development.  Probably required to establish thermotolerance acclimation.  Plays a role for controlled anisotropic cell expansion in the regulation of waving during root gravitropism and thigmotropism.  Involved in the root system architecture adaptation to multiple environmental conditions such as nitrate.  Contributes to salt tolerance and possibly to drought by preventing the overaccumulation of sodium ions.
What are the official names of this protein?
Chitinase-like protein 1, AtCTL1, Protein ANION ALTERED ROOT MORPHOLOGY, Protein ECTOPIC DEPOSITION OF LIGNIN IN PITH 1, Protein ECTOPIC ROOT HAIR 2, Protein POM-POM1, Protein SENSITIVE TO HOT TEMPERATURES 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACKA_SHEB8
Sequence: MSNNLVLVLNCGSSSLKFAVIDAQTGDDQISGLAECFGLEDSRIKWKINGEKHEAALGAFTAHREAVEYIVNKILAEQPELAAKIQAVGHRIVHGGEKFTRSVIIDESVIKGIEDCASLAPLHNPAHLIGIRAAIASFPKLPQVAVFDTAFHQSMPDRAYVYALPYKLYREHGIRRYGMHGTSHLFVSREAAKMLNKPIEETNVICAHLGNGASVTAIKGGKSVDTSMGLTPLEGLVMGTRCGDIDPSIIYHLVHQLGYTLEEVNNLMNKQSGLLGISELTNDCRGIEEGYADGHKGATLALEIFCYRLAKYIASYTVPLGRLDAVVFTGGIGENSDLIREKVLNMLEIFNFHVDSERNKAARFGKKGIITQDKGTIAMVIPTNEEWVIAEDSIKLINK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1A_RAT
Sequence: MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Involved in regulation of ionic conductances and long-term synaptic plasticity.  May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage.  Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development.  In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation.  May dephosphorylate CSNK1D and CSNK1E (By similarity).  Dephosphorylates CENPA (By similarity).  Dephosphorylates the 'Ser-139' residue of ATG16L1 causing dissociation of ATG12-ATG5-ATG16L1 complex, thereby inhibiting autophagy (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Primarily nuclear and largely excluded from the nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. NOM1 plays a role in targeting it to the nucleolus. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles (By similarity).
Protein: CAPS2_PFV1
Sequence: MSVEVYRQKIEKGGYSAAYEATRRYERGEIEVLSWSSRWESAWSKFGEAVKALGKIEGAPRALVIAKVQEALAYMSKPLPNMKLAMAAAVQAVRACEQLPGMNRERCLDAVAGALGVAKDWIRREMTGGGGGGGGGGGGGGGAVV
What is the function of this protein?
Self-assembles to form a helical, filamentous nucleocapsid.  Together with capsid protein 2, wraps arounds the DNA and maintains it in an A-form.  Capsid proteins probably maintain the DNA in A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues.  This certainly protects the viral DNA under conditions such as the extreme desiccation of its host.
What are the official names of this protein?
Major capsid protein 2, MCP2, Major capsid protein VP2.
What are the subcellular locations of this protein?
Virion.