PharMolix/UniProtQA huggingface dataset:
Protein: VATD_NEUCR
Sequence: MSGAADREAVFPTRQSLGIMKAKLKGAETGHSLLKRKSEALTKRFREITRRIDEAKRKMGRVMQIASLSLAEVTYAVGGNIGYQIQESAKSARFRIRAKQENVSGVLLPAFEAYQAEGNDDFAMTGLGKGGQQVQRCRETYARAVEALVELASLQTAFVILDEVIKVVNRRVNAIEHVIIPRTENTIKYINSELDELDREEFYRLKKVAAKKQRDNAETDAQMKAKKAEQQRLALADSENAEGEQTENTPADILAAEEDEDVIF
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit D, V-ATPase subunit D, Vacuolar proton pump subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PWP3A_BOVIN
Sequence: MTDAKYVLCRWKKRLWPAKVLAGTEKSAKNKRKKGYFLNVQILSLDKKIKVKSAEAKVLRKVHIEDIASSLASQDGTPAAPLEELTYRRSLRVALDVLNERQGSSSREGTTPRPPRVKPMEPASWPPKPSLSPSFLEDTAGSPGPTRRERMSQRLSGLPAGEEDLEYGVDHKEGLKRSGGLDAPAMCSASGGAQDREASRKQQADWMTPLGKQGRNPAQGPHSGQRVAPSSEGAGQEDGETGAGPAALCSPPGGRDLSPLDGCPAEHLGLDSGQRPRAHMSPHSPAQLGPAEEAADTRPLEEARPLSEEFMEPSAVNSLLEEDEDDEEPPRILLYHEPRSFEVGMLVWHKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPRGRGISVLLRRLKHFDCKEKQALLDEAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISSPVRKSIQQDVQGTRFPQLSGGDPEEPVAGSPQGRRPAYRKVLPDRSRAARDRANQKLVEYIVKARGAESHLRAILRNRKPSRWLKTFLSSGQYMTCVETYLEDEEQLDLVVKYLQGVYKQAGCQLLARGHGDGIRFILDVLLPEAIICAISAVDAVDYKTAEEKYIRGPALSSREKEIFDNQLLEERNRRC
What is the function of this protein?
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture.  Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation.  Required for efficient DNA repair and cell survival following DNA damage (By similarity).
What are the official names of this protein?
PWWP domain-containing DNA repair factor 3A, PWWP3A, Mutated melanoma-associated antigen 1, MUM-1, PWWP domain-containing protein MUM1.
What is the protein family that this protein belongs to?
Belongs to the PWWP3A family.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Protein: DAGK_STAAS
Sequence: MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: MCA3_ARATH
Sequence: MASRREVRCRCGRRMWVQPDARTVQCSTCHTVTQLYSLVDIARGANRIIHGFQQLLRQHQPQHHEQQQQQMMAQPPPRLLEPLPSPFGKKRAVLCGVNYKGKSYSLKGCISDAKSMRSLLVQQMGFPIDSILMLTEDEASPQRIPTKRNIRKAMRWLVEGNRARDSLVFHFSGHGSQQNDYNGDEIDGQDEALCPLDHETEGKIIDDEINRILVRPLVHGAKLHAVIDACNSGTVLDLPFICRMERNGSYEWEDHRSVRAYKGTDGGAAFCFSACDDDESSGYTPVFTGKNTGAMTYSFIKAVKTAGPAPTYGHLLNLMCSAIREAQSRLAFNGDYTSSDASAEPLLTSSEEFDVYATKFVL
What are the official names of this protein?
Metacaspase-3, AtMC3, Metacaspase 1a, AtMCP1a.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: GPDA_STAAS
Sequence: MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCHTNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPTKAMREVASQINDKLTSKKTFIHVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKSVSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTRGLAEISRLGEKLGADPMTFLGLGGIGDLIVTCTSTHSRNFTLGYKLGQGESMDQALSEMNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECVKDLMERDKKSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_BRUAB
Sequence: MPIKIPDDLPATSVLEAEGVMVMREADAVRQDIRPLRIGLLNLMPNKVTTETQIARLLGATPLQVELTLVRMTNHVARHTPADHMLSFYCPWEEVNDQRFDGFVITGAPVERLPFEEVTYWDEMRRVFDWTQSHVHRTLNICWAAQAAVYHFHGMKKYDLPAKASGVFRQRSLVPASPYLRGFSDDFAIPVSRWTEVRKSDIPADSGLKVLVDSTETGLCLLDDPRHRSLHMFNHVEYDTTSLADEYFRDIQVQPEAKVPVNYFPGDDAKRPPENRWRSHAHLLFGNWINEMYQSTPYDIERIGKV
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SHEON
Sequence: MAAKIRRQDEVIVLAGKDKGKRAKVAQVLPTGKLIVEGINLVKKHQKPNPQLGVAGGIVEKEAPIQASNVAIFNPVTGKADRVGFRFEDGKKVRFFKSNSELVK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PCMA_XANP2
Sequence: MNQAAVQLPLPGFEQASGQWRSDYSRQVAGEKPVRNRSGIEVQPLYSPRDWAGERYLDDLGFPGQYPFTRGIYPSMHRGRTWTQRQLIGLGTPQDYNVRVRRIIDAGATAISLLPCCSGFRGIDCDEVDPVLLGTCGTVVNTTDHMDAALDGVPLGTISTAMNDPSPFTLLAFTLGVARRRGIDWRSITGTSNQSDYISHFIANHQFYRLSLPGSRRVLLDHIEFCRRALPNWNPLSVVGQHMQQAGATPAETMGFTLSSAIQYAQDCIERGMDVDDVLRRFTFFFDISISFFEEIAKFRAGRRIWARIARERLGAKDPACWRFKFHGQTSGVDLTQQQPLNNIARVSVQAMAGILSGLQSMHTDAYDEAIACPSEETARIAVATQNILRDEAQLCAVIDPLGGSYYVERLTDQMEAEIEAVIARIDAAGGMYKAAEVGLVQTMIGESALAFQEQLETGERKIVGVNCYQVEEDPTIPPAERPDPEAMERHVERFKVFKRERSQDAVARALDALARAANSERENVFEKVVEAAEAGVTHGEMVGCLRRELGFGHPLIIA
What is the function of this protein?
Together with Xaut_5044, catalyzes the reversible isomerization between pivalyl-CoA and isovaleryl-CoA, using radical chemistry.  Does not exhibit isobutyryl-CoA mutase (ICM) activity.
What are the official names of this protein?
Pivalyl-CoA mutase large subunit, PCM large subunit, Pivalyl-CoA mutase, substrate-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA mutase large subunit family.
Protein: PYRF_PENNA
Sequence: MSSKSQLTYSARAQSHPNPLARKLFQVAEEKRSNVTVSADVTTTKELLDLADRLGPYIAVIKTHIDILSDFSQETIDGLNALAQKHNFLIFEDRKFIDIGNTVQKQYHNGTLRISEWAHIINCSILPGEGIVEALAQTAQATDFPYGSERGLLILAEMTSKGSLATGAYTSASVDIARKYPSFVLGFVSTRSLGEVESTEAPAQGEDFVVFTTGVNLSSKGDKLGQQYQTPQSAVGRGADFIISGRGIYAAADPVEAAKQYQQQGWEAYLARVGAQ
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: MVD2_PANGI
Sequence: MAKELQKWVVMVTAQTPTNIAVIKYWGKRDETLILPINDSISVTLDPDHLCTTTTVSVSPSFEQDRMWLNGKEISLLGGRFQSCLREIRSRACDLEDEKKGIKIKKMDWEKLRLHIASYNNFPTAAGLASSAAGLACFVFALAKLMNLNEDNGQLSAIARRGSGSACRSLYGGFVKWIMGKEENGSDSIAFQLADEKHWDDLVIVIAVVSARQKETSSTTGMQDSCKTSMLIQHRAKEVVPKRIIQMEDAIEKRDFPSFARLACADSNQFHAVCLDTSPPIFYMNDTSHKIISCVEKWNRSVGTPQVAYTFDAGPNAVLIARDRKIAALLLRRLLFHFPPTFQHCLNSYVIGDKSILQDVGVQDMKDIESLPPPPEIKDNIPAQKSNGDVSYFICTRPGRGPVLLPDSGALLNPETGLPK
What is the function of this protein?
Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids (By similarity).  Component of the triterpenes (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:24933610, PubMed:29378087).  Promotes the accumulation of stigmasterol and beta-sitosterol (PubMed:24933610).
What are the official names of this protein?
Diphosphomevalonate decarboxylase 2, Mevalonate-5-pyrophosphate decarboxylase, PgMVD.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: HIS4_SORC5
Sequence: MQLIPAIDLLGGQAVRLHQGRYDQVTVYDQDPAALAARLRRACARLHVVDLEGARAGLPVQADAVRAVIAAFGAEGGSVQVGGGIRSAAAAESYLALGADRIVLGTAAVNDPALVRDLAGRFPGRVVVAVDAKDGRVAVQGWEQVSSVTALDVARALAGAPVAALLYTDVSRDGTQVGPNLEATRELAASCGFPVLASGGVGSLAHLRALAQIPGVSGVIVGRALYEGAFTLAEAIEAASA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_STRP2
Sequence: MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAFRGVGSIEDVIAKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLMH_ECO8A
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_YERE8
Sequence: MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRAASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHIQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEADHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVEREGQKKMVIGNKGSKIKTIGIEARQDMEQMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: QUEA_ECO7I
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDDRSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRIQ1_HUMAN
Sequence: MDDDDAKLKAEIEAELDKLSISSLEKEDIESDAKSETQSDDSDTDSVELPESVLHCINIIKNRSKAVEELILQDLEDTDILSCSYGAVSNNHMHLRTGLSTEYEESSEQLIKILSEIEKEEFMRSKTDCATPDFVPEPSPHDLPMDEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLKEQFPLQELKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPKDNAWNSGIVIFNTTDTMINIEGKRNDQDYVLGRHAPCEGLSNYNAESSMVSKEVNSLKSEIRNISEKCHENAPEPDSMTCCVSESTLLYSIEERRLAWIKSFKPWLEIFKQNQQKKIVRRKRPVKCPANMTPALDKLEILRCGPWDTLQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCVVLLNKNQLTSLHGLDGCTNIQCLELSYNKITRIGYSFFLEEKLVDNAGFCHHLGTSTSYLSLAQVWIPTGLCWSWIPITSLTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRILNGNILNSNSESRTEEHNQLGSAGFLALCQSQIREFNLLIENYITGKGDVFTLDTAENLCHYFKKLMILSTEYRHAHERGDVTITKKDESEAQKNHLAPTNSDSTLQNGVFYSCAREGEPDSPDIPEKWMDSVSSHSPLSKSATCENMEGRHQEILVCQKREDSKASSIPTIRIPFKEVVMTNSLLRNHQNIEPSEKIMAAVVIQSYWRGYLMRRQTHFSTRLHTAATEGLPNSSIKNQTILKKGKRENIVNIRKQREKAAILIQAVWKGFILRKKLTTALEAIKNEESDEEYREIDLEDFIFDEAALEEEWLALDSTRFPSQTLLLSNQLHWPKIPGNLKWDDTSFNLPSNPAQAWLCNDKENLSSSEHTQFNSRSENKTSSWTPESKTSRKSLLKSEKEKKISEEWGFKDISTAQQMLKRAQKMKSKKLKKKIDSTVRLALFKNNENKVSLPKSPKMVQPRRDGYFEGIEEDPIHKDTTANEKLERNREYTYQWLHTQVGVHETTSSRNMKCNHFLPELDPDVLNGGRVQLVARLVSREDTDLDLFSMTNGSALSVNREKKNQAHRHSAGSSSKLWFPSKLI
What are the official names of this protein?
Leucine-rich repeat and IQ domain-containing protein 1.
Protein: COAX_CAUVC
Sequence: MMLLAIEQGNTNTMFAIHDGASWVAQWRSATESTRTADEYVVWLSQLLSMQGLGFRAIDAVIISSVVPQSIFNLRNLSRRYFNVEPLVIGENAKLGIDVRIEKPSEAGADRLVNAIGAAMVYPGPLVVIDSGTATTFDIVAADGAFEGGIIAPGINLSMQALHEAAAKLPRIAIQRPAGNRIVGTDTVSAMQSGVFWGYISLIEGLVARIKAERGEPMTVIATGGVASLFEGATDSIDHFDSDLTIRGLLEIYRRNTIAES
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_RAT
Sequence: METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGASGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSNEGRALRRQHQRNVKLMRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFLEKLLLTWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKAYFSGMSKMVSAQA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: KYNB_BURP1
Sequence: MDTIWDISPPIAPATPVWPGDTPVGIERVWRIEAGSPVNVARVTLSPHTGAHADAPLHYDADGTPIGAVPLDAYLGRCRVIHCIGARSAVTPEHVRAALAGAPPRVLLRTYGQAPQHAWNSAFCAVAPETIDLLAAHGVRLVGIDTPSLDPQESKTMDAHRRIRAHRMAILEGLVLDEIAAGDYELIALPLKFTTLDASPVRAVLRALPDAPR
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: PLMN_ERIEU
Sequence: MQRKELVLLFLLFLQPGHGIPLDDYVTTQGASLCSSTKKQLSVGSTEECAVKCEKETSFICRSFQYHSKEQQCVIMAENSKSTPVLRMRDVILFEKKMYLSECKVGNGKYYRGTVSKTKTGLTCQKWSAETPHKPRFSPDENPSEGLDQNYCRNPDNDPKGPWCYTMDPEVRYEYCEIIQCEDECMHCSGQNYVGKISRTMSGLECQPWDSQIPHPHGFIPSKFPSKNLKMNYCRNPDGEPRPWCFTMDRNKRWEYCDIPRCTTPPPPSGPTYQCLMGNGEHYQGNVAVTVSGLTCQRWGEQSPHRHDRTPENYPCKNLDENYCRNPDGEPAPWCFTTNSSVRWEFCKIPDCVSSASETEHSDAPVIVPPEQTPVVQECYQGNGQTYRGTSSTTITGKKCQPWTSMRPHRHSKTPENYPDADLTMNYCRNPDGDKGPWCYTTDPSVRWEFCNLKKCSGTEMSATNSSPVQVSSASESSEQDCIIDNGKGYRGTKATTGAGTPCQAWAAQEPHRHSIFTPETNPRADLQENYCRNPDGDANGPWCYTTNPRKLFDYCDIPHCVSPSSADCGKPKVEPKKCPGRVGGCVAHPHSWPWQVSLRRFGQHFCGGTLISPEWVVTAAHCLEKFSNPAIYKVVLGAHQETRLERDVQIKGVTKMFLEPYRADIALLKLSSPAIITDKDHPACLPNSNYMVADRSLCYITGWGETKGTYGAGLLKEAQLPVIENKVCNRQSFLNGRVRSTELCAGHLAGGVDSCQGDSGGPLVCFEKDRYILQGVTSWGLGCARLTRPGVYVRVSRYVSWLQDVMRNN
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation.  In ovulation, weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.  Also cleaves fibrin, thrombospondin and von Willebrand factor.  Its role in tissue remodeling and tumor invasion may be modulated by CSPG4.  Binds to cells (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).
Protein: PAND_BACCQ
Sequence: MFRTMMRAKLHRATVTEANLNYVGSITIDEDLMDAVNIVENEKVQIVNNNNGARLETYVIKGERGSGVVCLNGAAARLVQPGDKVIIICYGLVAEENIHKQEPKIAVLDDDNQIIEMLGAEKAGTIL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_HELPJ
Sequence: MIIERLVGNLRDLNPLDFNVDHVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSMPHSEPNFKVSLASDFKVVVK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_STRPC
Sequence: MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAVAPAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKSVFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRIIEVLEMDISN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: NIKR_HALSA
Sequence: MSVVSVSMPEELLERLDDFADDHGYTGRSEVVREASRNLLGEFEDKKLEGRELMGVVTVVFDYETTTVEEKMMHLRHEHEGLVASNFHSHVGGHHCMELFVLEGSLESISTFVGKIRATKDTLTIDYSVLPVDEFGGLADVS
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: ATPD2_PHOPR
Sequence: MSDLKTIAQPYAKAAFDFALANKSLDQWAYMLMTTAEVASQPVILQEIKEIDFKGAKNAEAFTQMFLDICEGLLDEHCQNFVRVMAENGRLIVLPDVLNLFMEMKADFERTIEATVLSVEPLTEEQKVNLVKALEKRLSRTVELDCQIDESLVGGMLIKAGELVIDGTLKSSINRLASSLQA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 2, ATP synthase F(1) sector subunit delta 2, F-type ATPase subunit delta 2, F-ATPase subunit delta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DDL_MACCJ
Sequence: MAKEHICIIYGGKSAEHDVSLLTAQSVINAMDKDKYAIDTIYITNDGEWLKGPEISETIEDSERLRLSHIERLSISEMLNVSSAGKAYDAVFPLLHGPNGEDGTIQGLFEVLDIPYVGNGVLAASTSMDKLVMKQLFATRGLPQLPYVSFLKSEYEAHKDNIISLVEGKLTYPVFVKPANLGSSVGISKCTDSETLIHGIEEALQFDRKLVIEQGVNAREVEVAVLGNDTPETTLPGEVVKDVDFYDYKSKYKDGKVRLQIPADISEEIQSALRDMAVEAFKATDCSGLVRADFFLTEDDKIYINETNAMPGFTKFSMYPLLWENMGKSYSELITDLINLAKERYKDKKNIKYKMD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSY1_CUCME
Sequence: MSSQVSNFPASIMKTNDIPDVKRSLANFHPNIWKEHFLSFTFDDALKIDEGMKERTEKLKEEIRMMMIAYVENQLIKLNLVDSIQRLGVSYHFEDEVDEFLEHIYVSYNNSLLLSNKNSNGEDLHITALLFRLLRQQGYRISCDIFLKFMDDNGKFKESLVEDERGLLSLYEASHMMGHGEALLEEALEFTTTHLQTYIHRYSNINPSFASEVSNALKLPIRKSVPRIKAREYLEIYQQHPSHNETLLEFSKLDFNILQKLHQKELSEICRWWKDLDVPTKFPFARDRIVECYFWTLGAYFEPQYSVGRKMLTKVIAIASILDDIYDAYGTFEELQVLTPAIQRWDRSMVHTLPLYMKPFYVAMLELYEEIGKEIDKDQNSLHLQVAIGGIKRLSESYFEEAKWLNKEYKPSFKEYMELALKTTGYTMLISISFLGLGDHIVTNEVLQWLSNGPQIIKASTIICRLMDDIASHKFEQEREHVASAVECYMKQYDCSEEEACIELHKEVVDAWKDTNEAFYRPFNVPVPVLMRVLNFSRVINLLYLDEDGYTNAKSGTKFLIKSLLVDPLPC
What is the function of this protein?
Sesquiterpene synthase producing mainly delta- and gamma-cadinene with traces of several other sesquiterpenoids, including alpha-copaene.  Associated with the production of sesquiterpenes responsible for the aroma of the fruit.
What are the official names of this protein?
(+)-gamma-cadinene synthase, CmTpsNY, (+)-delta-cadinene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.