PharMolix/UniProtQA huggingface dataset:
Protein: LKHA4_YEAST
Sequence: MFLLPFVIRHSSSIYLPTLRFRGLLTVISRNIHISTPHKMLPLSIEQRRPSRSPEYDQSTLSNYKDFAVLHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIEQRKEPLGSRLVINNASCNDNFTLNIQFRTTDKCTALQWLNSKQTKGGKPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESPLPVVFSGIRIEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPPRPHFITALADNVYQLADKWVEMAQHLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDWAKFPVASRALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGRMKFVRPGYRLLNSVDRRLALATFDKFKDTYHPICKALVKQDLGL
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leucyl aminopeptidase yscIV, AP IV, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TSAD_BURP0
Sequence: MLVLGIESSCDETGLALYDTERGLLAHALHSQIAMHREYGGVVPELASRDHIRRALPLLEEVLAASGARRDDIDAIAFTQGPGLAGALLVGASIANALAFAWDKPTIGIHHLEGHLLSPLLVAEPPPFPFVALLVSGGHTQLMRVSDVGVYETLGETLDDAAGEAFDKTAKLLGLGYPGGPEVSRLAEAGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKLEAAHAGGAVLERAKADFARGFVDAAVDVLVAKSLAALKATRLKRLVVAGGVGANRQLRAALSAAAQKRGFDVHYPDLALCTDNGAMIALAGALRLARWPSQASRDYAFTVKPRWDLASLAR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P2_DANRE
Sequence: MSELCVGINGFGRIGRLVLRACLQKGIKVTAINDPFIDLQYMVYMFKYDSTHGRYKGEVHMEDGKLIVDGQAISVFQCMKPAEIPWGDAGALYVVESTGVFLSIEKASAHIQGGAKRVVVSAPSPDAPMFVMGVNQDKYDPSSMTIVSNASCTTNCLAPLAKVIHDNFGIEEALMTTVHAYTATQKTVDGPSAKAWRDGRGAHQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPVADVSVVDLTCRLTRPASYANIKESVKKAAHGPMKGILGYTEDSVVSSDFVGDTHSSIFDAGAGISLNDNFVKLISWYDNEFGYSHRVADLLMYMHSKE
What is the function of this protein?
Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_ACAM1
Sequence: MQQMATGLAVTGCGSAAPETSLDNHGLSQIVDTSDEWIASRTGIRSRHLAGPDDTLAKLGAIAAQNALEMAQVEATDLDLILLATSTPDDLFGSACQIQAAIGAKHAVAFDLTAACSGFVFGMITAAQFIRTGVYRNVLLVGADVLSRWVDWTDRRSCVLFGDGAGAVVLQANDTDRLLGFALHSDGCLHDCLNVQYQGEARPLTGEINVSQGTYQPISMNGKEVYRFAVNRVPEVVEKALFQSDLKTDDIDWLLLHQANQRILDAVAKRLKVPAEKVISNIANYGNTSAATIPLALDATVRKGHIKPGDTIAASGFGAGLSWGAAIFQWQR
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_MICAN
Sequence: MAKRMQVILNQKVSKLGENGDVVEVAPGYARNYLIPQGVAVLATKGAIKQAEFRKEKERQRLLAEKQEAETRKTAIEKLSPYSIPKQVGENEAIFGTVTSQDVATVILENAKLEIDRRGITVPDIGQLGVYKVQVKLHPEVSADIEIKVIAQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ARTM_SHIFL
Sequence: MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
What is the function of this protein?
Part of the ABC transporter complex ArtPIQMJ involved in arginine transport.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Arginine ABC transporter permease protein ArtM.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XPO7_PONAB
Sequence: MADHVQSLAQLENLCKQLYETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAATCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQKDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFRDSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTDESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSIPPSFSPLVLSCLVQIASVRRSLFNNAERAKFLSHLVDGVKRILENPQSLSDPNNYHEFCRLLARLKSNYQLGELVKVENYPEVIRLIANFTVTSLQHWEFAPNSVHYLLSLWQRLAASVPYVKATEPHMLETYTPEVTKAYITSRLESVHIILRDGLEDPLEDTGLVQQQLDQLSTIGRCEYEKTCALLVQLFDQSAQSYQELLQSASASPMDIAVQEGRLTWLVYIIGAVIGGRVSFASTDEQDAMDGELVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYRRLSEVLGLNDETMVLSVFIGKIITNLKYWGRCEPITSRTLQLLNDLSIGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTALGRLLMVDLGEDEDQYEQFMLPLTAAFEAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEWIYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSRRLQFDVSSPNGILLFRETSKMITMYGNRILTLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFGVFRLYGDDALDNALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNQESDRFLHIMQQHPEMIQQMLSTVLNIIIFEDCRNQWSMSRPLLGLILLNEKYFSDLRNSIVNSQPPEKQQAMHLCFENLMEGIERNLLTKNRDRFTQNLSAFRREVNDSMKNSTYGVNSNDMMS
What is the function of this protein?
Mediates the nuclear export of proteins (cargos) with broad substrate specificity.  In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor.  XPO7 then return to the nuclear compartment and mediate another round of transport.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Exportin-7, Exp7.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nuclear pore complex. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PARC_SALTY
Sequence: MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTEAEIITPRAEIRKIYENGRGSVRMRAVWTKEDGAVVISALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRSEDEPKPALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGILASERKMNTLLKKELQADADAYGDDRRSPLREREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITLPSARGQGEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKTLITLPENAHVMPPLVIEDEHDMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKGDDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGERGRRGTLMRGLQRIDRIEIDSPHRVSHGDSEE
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA (PubMed:22916023).  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LIPB_NEIG1
Sequence: MKIIHKGLVEYLPTFEAMKTFNAGRNADTEDELWVVEHPPVFTQGLAGKPEHLLIRDDIPVVQIDRGGQITYHGPGQLVVYTMIDFKRRKTSVRNIVSALENSIIATLAEYGIEAAADPKRPGIYVGERKIASLGLRIKNGSVYHGLALNVNMDLSPFTQINPCGYAGMEMTQIADFVQPCPAPDEVASKLTAHLETQLTPKADNNE
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOWR_MOUSE
Sequence: MSGSGAAGAAAGPAPPAQEEGMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLNIAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL
What are the official names of this protein?
Calcium channel flower homolog, Calcium channel flower domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel flower family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRMA_CLOK1
Sequence: MSKEWIEVSIIVSSEAVEAVSGILYNTEVEGISIEDTKDIEFKKKHPGDWDYFDESLLKVEEGAVIKAYYRESESFYGYLKYIRHNINNLENLGIDKGKGLVVVNKVNEEDWENGWKKYYKPYRAGEKIVIKPLWEEYENKKQDIVVEIDPGMAFGTGTHETTKMCIKALEKYVRPESNVFDIGTGSGILAIAASKLGAKEVTAVDLDPVAVESALKNISYNNIKNIKVFHGNLMEGVHGKADILVINIIADVILSLTEEVKKFLVSEGIFISSGIIIDRKEEVVENLQNNGFCIREINEDGEWVCIVSTIK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLP3L_MOUSE
Sequence: MTTLTHRTRRTEVSKSSEKKIESEEDTNQERSPDNEDPGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLMKKLQDSVLERWVNDPQRMDRRTLALLVLAHSSDVLENVFSCLTDDKYDVAMNRTKDLVELDPEVEGTKHNATEMIWAVLAAFNKS
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
What are the official names of this protein?
Golgi phosphoprotein 3-like.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol 4-phosphate (PtdIns4P)- binding mediates recruitment to Golgi membranes.
Protein: ISPH_RHOE4
Sequence: MSSAVPLNLGIAHSADSPSTRKGSAKRVLLAEPRGYCAGVDRAVETVEKALEKHGAPIYVRKEIVHNRHVVETLEDQGVIFVDETDEVPEGSLLVFSAHGVSPAVHDSAAERNLRTIDATCPLVTKVHQEAKRFARDDYDILLIGHEGHEEVEGTAGEAPDHVTIVDGPDSVDAVTVRDESKVIWLSQTTLSVDETMQTVARLRERFPNLQDPPSDDICYATQNRQVAVKAMAPECDLVIVVGSRNSSNSVRLVEVALGAGAAASYLVDYAREVDLAWLEGVQTVGITSGASVPEVLVRGVIELLAEHGYNDVQPVTTANETLVFALPRELRAARTS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: URE2_MYCBT
Sequence: MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIVGLVPLGGRREVPGLTLNPPGRLDR
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y891_ARCFU
Sequence: MDTYAIISFLLGIAFGFLRRGKEDRAKIIEVIFVSLLLGLVSGIALSHAVLDGAGWGEFVKAFGLIVAALIYAIFFAAGTYLGDLLEKLRK
What are the official names of this protein?
Uncharacterized protein AF_0891.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNSP2_BOARA
Sequence: MAFLKKSLFLVLFLGIVSLSICEEEKRVGEEEEKQEEENEELSEEELRERRAWLDKLKSLGKVVGKVAIGVAQHYLNPQQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Raniseptin-2, Rsp-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YD541_YEAST
Sequence: MSNTVLVSGASGFIALHILSQLLKQDYKVIGTVRSHEKEAKLLRQFQHNPNLTLEIVPDISHPNAFDKVLQKRGREIRYVLHTASPFHYDTTEYEKDLLIPALEGTKNILNSIKKYAADTVERVVVTSSCTAIITLAKMDDPSVVFTEESWNEATWESCQIDGINAYFASKKFAEKAAWEFTKENEDHIKFKLTTVNPSLLFGPQLFDEDVHGHLNTSCEMINGLIHTPVNASVPDFHSIFIDVRDVALAHLYAFQKENTAGKRLVVTNGKFGNQDILDILNEDFPQLRGLIPLGKPGTGDQVIDRGSTTDNSATRKILGFEFRSLHESVHDTAAQILKKQNRL
What are the official names of this protein?
Putative uncharacterized oxidoreductase YDR541C.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: SC5A9_DANRE
Sequence: MPASPEPVTATPEPEEVPAKFTLEAADIAVVVVYFVFVLAVGIWSSIRANRGTVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNAAWVLIALGWIFVPVYISAGVVTMPEYLRKRFGGQRIRIYMSVLSLILYILTKISTDIFSGALFIQVSLGWDLYLSTVILLAVTALYTIAGGLTAVIYTDALQTVIMVIGAFVLMFIAFDKVGWYEGLLVQYEKAAPALTVPNTTCHLPRSDAFHIFRDPVTGDIPWPGLIFGLTVLATWVWCTDQVIVQRSLSAKNLSHAKAGSVLGGYLKVFPMFFVVMPGMISRALYPDEVACVDPDECQKICGAKVGCSNIAYPKLVVELMPVGMRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWQRIRPRASEKELMVVGRVFILLLVALSIVWIPVIQTANSGQLFDYIQAITSFLSPPITTVFIMAIFWGRVNEQGAFWGLMVGLVVGMVRMIMEFVYGTPSCGETDLRPSLLKDVHYLYFALILLALTVLIITAVSLCTAPIPEKHLVRLTWWTRHSKEERVELEDPWAKPAGSDLSTTESEGSDEDAPAWWKRAGMWLCGLSQTTKQDLTEEERQALEKKLTSIEEDHMWKTVCNVNALILLTANVFLWGYFA
What is the function of this protein?
Probable sodium-dependent sugar transporter.
What are the official names of this protein?
Sodium/glucose cotransporter 4, Na(+)/glucose cotransporter 4, Solute carrier family 5 member 9.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AAEB_RAHSY
Sequence: MNSVLIPRVRFACKLTFAILGALVLGFYLQLETPRWSAMTAAIVTSGPALAAGGEPFAGAIRHRGFLRVIGTFIGCIAALVIVIATARAPVVMLLLCCIWAGVCTWWSSLVRIENSYALGLAGYTALIIVVTSASSPLQTPQFAVERCSEIVIGICCAIVADLLFSPRSIKKDIDRAVSQLMLDQFALMRICVNSGTKEEIDKSWNNLVKSTTALNGMRGSLMMESSRWQRCNRRLKALHSTSLSMITQACETYLIMQSSPERVSPELKALFAEPAENVADVHRRLKQLRQMITGMHSDNVLMTVSAWTGAGTRALLLMKGIQTNSSISAIESGVLDGEVVVRPVSAERHHALVNGLRTFTATTIGCLMWLWTGWTSASGCVIIIAVVTSLAMRTPNPKGMAMDFIIGMLLAIPVGSMMFMLIMPATQQSLFLLCLMLGIFTFFIGIEVTKRRLGMLGLLAGTINILVLSNPMVFNVTSFLDNAMGQAIGTVIAMAVLLIVRDKSREKTGRTLLNRFMSSAVSALTTKAYRRRENHLPALYHQLNQLLVMFPNDIGKYRLALMLIIAHQRMKLAEVPVNDELSAFHKKIRNTADHVVSASGEGKRTYYYQRLLKELGEYQEKLVEYDAPLKVTEPVRRLTDMLQRYQHAFLA
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_SYNS9
Sequence: MALLHSANPADQIIVALDGMAPDQALAFSVQVEGLRWVKVGLELFVQAGPEVVAQLREQDLRVFLDLKFHDIPATMAGACRRAAALGAELITVHACAGSEALNAAQSAAMEGAQSSGQPSPTLLAVTVLTSWEEQRLQRELAISQGIAPRVSALAQLSATAGIGGCVCSPWEAAALRAQHPEPFALITPGIRLKGAAVGDQARVMGPAEAMTAGATQLVIGRPITRANDPSAAFNACCRELRT
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: POLG_DEN2U
Sequence: SAGMIIMLIPTVMAFHLTTRNGEPHMIVSRQEKGKSLLFKTEDGVNMCTLMAMDLGELCEDTITYKCPLLRQNEPEDIDCWCNSTSTWVTYGTCTTTGEHRREKRSVALVPHVGMGLETRTETWMSSEGAWKHAQRIEIWILRHPGFTIMAAILAYTIGTTHFQRALIFILLTAVAPSMTMRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEAKQPATLRKYCIEAKLTNTTTESRCPTQGEPSLNEEQDKRFVCKHSMVDRGWGNGCGLFGKGGIVTCAMFTCKKNMEGKVVQPENLEYTIVVTPHSGEEHAVGNDTGKHGKEIKVTPQSSITEAELTGYGTVTMECSPRTGLDFNEMVLLQMENKAWLVHRQWFLDLPLPWLPGADTQGSNWIQKETLVTFKNPHAKKQDVVVLGSQEGAMHTALTGATEIQMSSGNLLFTGHLKCRLRMDKLQLKGMSYSMCTGKFKVVKEIAETQHGTIVIRVQYEGDGSPCKIPFEIMDLEKRHVLGRLITVNPIVTEKDSPVNIEAEPPFGDSYIIIGVEPGQLKLNWFKKGSSIGQMFETTMRGAKRMAILGDTAWDFGSLGGVFTSIGKALHQVFGAIYGAAFSGVSWTMKILIGVIITWIGMNSRSTSLSVSLVLVGIVTLYLGVMVQADSGC
What is the function of this protein?
Disrupts the host endothelial glycocalyx layer of host pulmonary microvascular endothelial cells, inducing degradation of sialic acid and shedding of heparan sulfate proteoglycans.  NS1 induces expression of sialidases, heparanase, and activates cathepsin L, which activates heparanase via enzymatic cleavage.  These effects are probably linked to the endothelial hyperpermeability observed in severe dengue disease.
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Peptide pr]: Secreted. SUBCELLULAR LOCATION: [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 1]: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=Located in RE-derived vesicles hosting the replication complex.
Protein: LUTA_ALKCK
Sequence: MNVSLFVTCLADIFYPGVGKDTVEVLERHGCNVKFPENQICCGQPAFNSGYHEDTKKAAKHTIETFADADYVVLPSGSCAAMLLEYKELFADDPEWEKRAEELASKTYELTQFLVRVLKVEDIGAVCHKKATYHTSCHMSRLLRETEAPFSLLEQVKGLELAPLANKESCCGFGGTFSVKMPAISEQMVEEKVGHIEATGADLLIGADCGCLMNIGGRIERNGKTIEVKHIAQVLNSKE
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: ASAP_DROME
Sequence: MPPSLIAVSEFVEETRSDYSSPTTSTFASRMPDCRHTIGVLEERLEFDREGLTKLKKAVKAIHNSGNTHVDNEMFMVRALERLGGKVIEQDEPDIGAAFLKFSVVTKELSALMKTLMQNINNIVMFPVDSMLKSELRGVKGDMKRPFDKAAKDYEAKFIKIEKEKKAQAKEAGMVRTEIDAAVVAEEMEKERRLYQLQTCEYLLKYKDIKTKTGIELLQHLIEYYHALSNYFKDGLQTIEHFGTYIGDLSEKLHEIKQKQDEDRRSLLDLRTVLRSTPDFERVDNVPSSESRSGGAGYSLHQLQGDKHHGVTRQGHLLKKSEGKVRRVWQKRRCRVTSDGFLDIFHADESKPPTRVNLLTCQIKPVPDDKRGFDLISYNRPYHFQAEDEGDQKAWMAVLVNCKEKALTKAFQHANPQMSPSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLLIARAMGNSTLNDIMEAKLGRGKLQHESSMEERYDFIRAKYVAKRYVMRTCSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPSSDAGETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTALDIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKSRSRPPSFAGGDSPVLRSRSSTCDSIQSSSSPIANCPSRQFTLPSGLPSYTHSAGTSPKQHISVGQYLGSATNVGGNGPGNGGSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLKKRTAPAPPPGTLGSASSSSFYGTLPHPPRHSQNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRGGGGYGYGVSQDPGGSGNGSNNSLMPAMTTFGHKRSPSGESLNRNIHLAGAKLVLPPTGELPTLKHVDKSALTRPKIPPPGPPSEREISNGQSNESISSMDEGPVAPPRKLVNQSANFPDYESWHTDMDSSGGGLDHSAESNVSSSDNDRLNSSPDNPSKTGGAGLGGKFHYNGQRRCRALYDCVADNDDELEFKEGEILIVLNERTDDENWMEGIIEGQPTRKGMFPVSFVHMLPD
What is the function of this protein?
Probable GTPase-activating protein (GAP) for Arf family proteins (Probable).  Involved in Golgi apparatus organization by targeting Arf1 to the Golgi, which may be important for membrane trafficking during epithelial morphogenesis (PubMed:27535433).  Regulates the positioning of interommatidial precursor cells during compound eye morphogenesis together with Arf6 and Cindr (PubMed:21976699).  Required for cleavage furrow ingression in early embryonic cells (PubMed:27535433).
What are the official names of this protein?
ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Cell projection, microvillus. Note=Detected in large puncta at the plasma membrane (PubMed:21976699, PubMed:27535433). Excluded from the nucleus at interphase (PubMed:27535433). Enriched in the nucleus at prometaphase (PubMed:27535433).
Protein: RK2_SOLTU
Sequence: MAIHLYKTSTPSTRNGTVDSQVKSNPRNNLIYGQRRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKRWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.