PharMolix/UniProtQA huggingface dataset:
Protein: ZN441_HUMAN
Sequence: MDSVAFEDVAINFTCEEWALLGPSQKSLYRDVMQETIRNLDCIGMIWQNHDIEEDQYKDLRRNLRCHMVERACEIKDNSQCGGPFTQTQDSIVNEKIPGVDPWESSECTDVLMGRSSLNCYVRVDSEHKPCEYQEYGEKPYTHTQCGTAFSYQPCFQIHERPQHGKKLYDCKECASFSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTHTEEKPYEYEQCSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSPSLCRRHETTHTGEKPYKCECGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGKALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHCISSFHKHEMTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 441.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXH_LEGPA
Sequence: MSKFRSLADIRRDYGELQLSEESAENDPISQFKLWFDDVLLNEKNDPTAMVLSTVDEKGYPDSRVVLLKGLENGNFIFYTNYQSAKAMQIQKNPYAALNFYWPQMARQVRVRGRVKKISSEQSDAYFSSRPLKSQFSAIVSPQSQEILDRISLEDALNQLIEEYGQKPVVRPENWGGYMIIPDEIEFWQGRDNRLHDRIHYYRHGHEWTHRRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: NTE1_PHANO
Sequence: MAAPDAMTSLVKSSVALLSSAHESLPTSLAAMKTAETAPSSTFGILGRVILSILSVLPTLLFWVSYTLPTWLFTLFSMSLTFTMNFTTLMLVLVFVVSTISYFVRYRYLTMYARLPPEPQREEPQVEVFPESQEGDSKRGLSNYLDEFLSAIKVFGYLERPVFHELTRTMQTRRLAAGETILLEEEKGFCLVVDGLVQIFVKSNREESDSDEDDGELQGESGGGSAQAHRQGYQLLTEVKNGAPMSSLFSILSLFTEDVKLRHDEDSGPSSSTPMSPQHRPSMTRNSSFNMDDSRPETPIEAQEATIRRRRTSALASPTAGGRLSNVPPLSLDTDGFNDNFKHSKQRRSPSRSTKPKSAHPDIVARATVDTTIAIIPATAFRRLTRIYPKATAHIVQVILTRLQRVTLATSHAYLSLTNEVLRTEKLMNKYTTYDLPGFLRDAPLERLKEKFTKETERLGSDEGMKGIALHNPGAGRRRRTSVSIRSSTAAQARLAAARGTSIGSNVEAISRLTSPEQGMRNDRISAGDLLTNTQMSRGTGRSGRSSFSQPYQHDVRRDARTPLDASGFNPFASPSMRPNLHRQESIDEATVFRESVLGCMFKAIGLTSPENPVPRPAASVEQSPRLVSFDAKRQKAIFTSAFGFMDPYEASRDGDADSVASASNLSTLSASGNGNLLEEVVNDVEIVFFPKDAVLVEQGERNPGLYYVIDGFLDVSVAVEEDSSESNVLGTLPTGPAVTEDDLFGPPLQPTATNTSLRNGENSKKKRSRKSLFMTRPGGLAGYLGTVSSNRSFVDVTAKTDVYVGFLPRASIERIVERYPVVLLTMAKRLTTLLPRLIQHIDFALEWVQVNAGQVIYNQGEESDAIYIVLNGRLRAIKDAENGKVTVIGEYGQGDSVGELEVLTETARPGSLHAIRDTELAKFPKTLFNSLALEHPGITIKISKIIASRMRALVDDPLHEQSKERSNKATRTNVSSTVNLRTVAILPVTAGIPVVDFASRLMNALNQIGVPRGVVSLNQAAILNHLGRHAFNRMGKLKLSQYLADLEEKYGMVLYVADTPVKSPWTQTCISQADCILLVGLAESSPNIGEYERFLLTTKTTARKELVLLHAERYCPSGLTRKWLRNWPWINGSHHHMQMSFRATAEPVHQTGRRLGNAIKQRVQVIQAEIQKYTSKRVRQTPLYSADTPFKGDFHRLARRLCGKSVGLVLGGGGARGISQIGIIRALEEAGIPIDIVGGTSIGSFIGALYAWDADVVPMYGRAKKFSGRMGSMWRFALDLTYPSASYTTGHEFNRGIFKTFGNSQIEDFWLEFYCNTTNISKSRSEIHTSGYVWRYVRASMSLAGLLPPLCDNGSMLLDGGYIDNLTVAHMKSLGADVIFAIDVGSLDEDTPQAFGDSLSGFWATFNRWNPFSTHANPPTLSEIQSRLAYVSSIDALERAKNTPGCRYMRPPIDPYGTLDFAKFEEIYEVGYKYGKGFLAQLREQGVLPVTEETEKEKNLRRTMAPRRASI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RCEL_ACICY
Sequence: VGPFYVGFFGVTAAFFIMLGTALIIWGAALGPTWNIWQISIAPPDLSYGLGLAPLAKGGLWQIITVCAIGAFGSWALREVEISRKLGIGLHVPAAFSVAIFAYVTLEVIRPLLMGAWGNGFPYGIMSHLDWVSNTGYAYLNFEYNPMHMVAVTLFFTTTLALALHGSLVLAAINPPAGETVKFAEHEDTFFRDFIGYSIGTLGIHRLGLFLALGAGFASATCILLSGPFWTQGWPSWWGWWLHLPIWQFGGH
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPON2_HUMAN
Sequence: MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARALAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSPCPELEEEAECVPDNCV
What is the function of this protein?
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons.  Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria.  Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity).  Binds bacterial lipopolysaccharide (LPS).
What are the official names of this protein?
Spondin-2, Differentially expressed in cancerous and non-cancerous lung cells 1, DIL-1, Mindin.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL4_BIFAA
Sequence: MANVTLNVTDNQGKATGTVDAPAEIFGFSAEEVQSRIPLIHQVVIAQLAAARQGTHATKTRGMVSGGGRKPWKQKGTGRARQGSIRAPQWYHGGTVFGPQPRDYSQRTPKKMKAAALKYVLSDRANAGHVAVVDFGVSEAPSTKAAVAALTPVTENKFTTVVLSRENVNEWLSVRNIPTVHPIFADQLNTYDVVTAQYVVFSKEGFDAFLAAKAEPAAKEA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FETP_SHEB9
Sequence: MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNISKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKEVEIEGFVPEKDQD
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RL5_BURP1
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAVADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PNP_PSEP1
Sequence: MNPVIKTFQFGQSTVTLETGRIARQATGAVLVTVDNDVTVLVTVVGAKQADPGKGFFPLSVHYQEKTYAAGKIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGFMNEVQVVCTVVSTSKKTDPDIAAMIGTSAALAISGIPFEGPIGAARVAFHESTGYLLNPTYEQLAASSLDMVVAGTSDAVLMVESEAQELTEDQMLGAVLFAHDEFQAVIQAVKELAAEAGKPTWDWKPAVANTELFNAIRAEFGEAVSQGYTITVKADRYARLGELRDQAVAKFSGEEGQPSASEVKDIFGEIEYRTVRENIVNGKPRIDGRDTKTVRPLNIEVGVLPKTHGSALFTRGETQALVVATLGTARDAQLLDTLEGEKKDPFMLHYNFPPFSVGECGRMGGAGRREIGHGRLARRSVQAMLPAADVFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPMKAPVAGIAMGLVKEGDKFAVLTDILGDEDHLGDMDFKVAGTAKGVTALQMDIKINGITEEIMEIALGQALEARLNILGQMNQVIGQSRTELSANAPTMIAMKIDTDKIRDVIGKGGATIRAICEETKASIDIEDDGSIKIFGETKEAADAAKQRILGITAEAEIGKIYVGKVERIVDFGAFVNILPGKDGLVHISMLSDARVEKVTDILKEGQEVEVLVLDVDNRGRIKLSIKDVAAAKASGV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_YERPG
Sequence: MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLLYGFNNKQERALFRELIKVNGVGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADIEAEAASALVALGYKPQEASRLVSKIAKPGADCETLIRDALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SLD3_SCHPO
Sequence: MNNDHASKKSFCIKAPSNWEKSYLEVWPLVTVPRQCICLRWCISKEYHEFTCSSLQFIVIRPAGTSVLLGRVKSSKANQLVGIEHVEGSRYALIFLSEKLDFKSLKVIANHQLTKSSKSLSNVSNKPLGDQLFRSNSLMSPSLLKKELHRIQSDASQANERESQAPHSFVTHDLISSSKDGNSLTHEFANDSVTEMVQDYTPSCSRDVKSLLDHLYNSYFYQLLMTKTPVVFYVKQMVGKTRQLAVEVHNHVEEKALVDELLKFLDNLKSVDDRKSRLLQCFESHLNYKAWHLEFENEAHQYEIKGYRLWLQNILNRENCQITKLDFEREFSQLKLKEYEIRVLLYFEILYLFLKWDPEYARRRANDNSLLDSRDSGKRKSRKKNAKTLNPFETAQLKLEFTFDGLCIRRTIEQNATERSEDLLLKFCKETIVPYYSSKFPRITRNLLEKCNGLDLLPERSHKHRHSAPPRSKLISSKSEAGRALPGNTSGASISNTSSPHSEASISKDYEILKRRRSNSGVHSLTRSDSSFNGFERDTRRRSSDIARIKNREINLPSSSLSKQRNSMHDISTNFPRRNLSFTEKLTMASLQGQSEESVQPKTTSSLSRSKTLSILEGSVSKRSEPSMDSILVQATPRKSSSVITELPDTPIKMNSLDKASACTVENHIVTESPAHKSNKAQLFVCVPTTPVKKKSASP
What is the function of this protein?
Required for loading and maintenance of stable association of cdc45 with chromatin during initiation and elongation of DNA replication.  Also involved in temporal regulation of origin firing.  Plays a role in meiosis.
What are the official names of this protein?
DNA replication regulator sld3, Meiotically up-regulated gene 175 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIM_LACLS
Sequence: MSILGKIQRTQPLILNLANFLTPQRVADVISFIGASPLMTSEIAELESLVEISDAVVVNIGTISESTYPLFLEACRLANQKAKPLILDPVAVNVPFRASIVKRLSQEVKFNIIRGNSAEIAWFADKKSLNKGIDALESNIDNEHARLAAKKTGAVIIETGKVDIISKGHEEMYVDTDSPLFKINVGCGDMLTAVVGTFAAVSDDLFTAAYEATKFFGEAGMIATKQVQNLPGNFVNSLLDTLYQATQEIK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YACG_EDWI9
Sequence: MENEIITVACPTCGSAVIWGEQSPYRPFCSKRCQLIDLGEWANEEKRIASDATHSDSEEWSEVDDR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: S22A9_BOVIN
Sequence: MAFQDLLDQVGGLGRFQILQMLLLCISSLITYPHILLENFTAAVPGHQCWVHILNNNTDSANATGTLSPDALLRISIPLDSNLRPEKCRRFSRPQWQLLNLNRTFPNITDLDTESCVDGWVYDQSIFTSTIVTEWDLVCESQSLKSMAKFLFMAGMLVGSIVYGHLSDRFGRRLIFRCCLLQLAITDTSAAFAPTYLIYCSLRFLAGFSTMSILTNCTVLIVEWTVPRFQVMGMTLSICAACLGQIILGGLAFAIRDWHTLQLVFSVPLFVLFLSSRWLAESARWLIITNRPEEGLKELKKAAHRNGRKNAGDALTMEVLRSAMQEELEAAQIKSSVFDLFRTPNLRKRICLLSFVRFANFMSFFGLILHLQYMGSNVFLFQVLFGAVNLPANCVAFWALNHLGRQVSQTLFLFLLGISILAITFVPQEMQTLRMAVSALGIAVSSVTLMCSFAHGNELTPTVLRVTASGFLGIASNIGAALAPLLMILTVYSPHLPWIIYGVCSILGGLVVPLLPETRNKPLPDSIQEVEKERKDSRKAKPEGTFMKVTQF
What is the function of this protein?
Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS).  Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised.  It is specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate).  May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes.
What are the official names of this protein?
Organic anion transporter 7, bOAT7, Organic anion/short-chain fatty acid exchanger, Solute carrier family 22 member 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein. Note=Enriched at the sinusoidal part of the plasma membrane.
Protein: TEG4_HHV1E
Sequence: MELSYTTTMHYRDVVFYVTTDRNRAYFVCGGCVYSVGRPYASQPGEIAKFGLVVRGTGPDDRVVANYVRSELRQRGLQDVRPIGEDEVFLDSVCLLNPNVSSELDVINTNDVEVLDECLAEYCTSLRTSPGVLISGLRVRAQDRIIELFEHPTIVNVSSHFVYTPSPYVFALAQAHLPRLPSSLEALVSGLFDGIPAPRQPLDAHNPRTDVVITGRRAPRPIAGSGAGSGGAGAKRATVSEFVQVKHIDRVGPAGVSPAPPPNNTDSSSLVPGAQDSAPPGPTLRELWWVFYAADRALEEPRADSGLTREEVRAVRGFREQAWKLFGSAGAPRAFIGAALGLSPLQKLAVYYYIIHRERRLSPFPALVRLVGRYTQRHGLYVPRPDDPVLADAINGLFRDALAAGTTAEQLLMFDLLPPKDVPVGSDVQADSTALLRFIESQRLAVPGGVISPEHVAYLGAFLSVLYAGRGRMSAATHTARLTGVTSLVLAVGDVDRLSAFDRGAAGAASRTRAAGYLDVLLTVRLARSQHGQSV
What is the function of this protein?
May participate in DNA packaging/capsid maturation events.  Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 into virions.  May also play a role in capsid transport to the trans-Golgi network (TGN) (By similarity).
What are the official names of this protein?
Tegument protein UL21.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae UL21 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: DUSB_VIBPA
Sequence: MKIGNYQLKNNLIVAPMAGVTDRPFRELCLRYGAGMAVSEMMSANPKLWKTSKSKQRMVHEGESGIRSVQIAGSDPQLMADAAQFSVENGAQIIDINMGCPAKKVNKKLAGSALLQYPTIIEEILKAVVNAVDVPVTLKTRTGWDTDNKNCVQIAKLAEDCGIQALALHGRTKACMYKGEAEYDSIKAVKEAISIPVIANGDIDSPEKAKFVLEYTGADALMIGRPAQGRPWIFQEIHHYLENGTTMDELPTQEVKAIMLGHVNALHEFYGEYLGPRIARKHVGWYLKEHEQASEFRRTFNAIDAAPLQIEALEGYFDNVAS
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: Y1546_STAS1
Sequence: MVSKIDGKLFAEMIIQGAQNLSNHADLVDSLNVYPVPDGDTGTNMNLTMTSGREAVENNLSQQIGELGKTFSKGLLMGARGNSGVILSQLFRGFSKSLETYETINAKQFAESFKAGVDTAYKAIMKPVEGTILTVARDAADAAIQKAEETDDCIELMAYILEEAEVSLENTPNLLPVLKEVGVVDSGGKGLAIVYAGFLKALKGETISAQSPKLNKESLVNEEHDFHGVINTEDIVYGYCTEMMVRFGKNKKTFDEQNFREDMSQFGDSLLVINDEEIVKVHVHTEKPGDVFNYGQQYGELIKLKVENMREQHREVVKKEHDGGKAISTEETQAVDTAVIAISMGEGISEIFKSMGATHMISGGQTMNPSTEDIVKIIEQSQCKRAIILPNNKNILMASEQAAEIVEADTIVIPTKSIPQGIAALFNYDETDSLESNKSRMVESLEAVRSGSVTYAVRDTKIDGVEIKKDAFMGLIEDKIVTSHADQFETVKGLMAEMINEDSEIITMIVGMDADKTVTSDIEDWMEATYPDVELEQHDGQQPVYQYLFSVE
What are the official names of this protein?
Uncharacterized protein SSP1546.
Protein: KBX2_TITST
Sequence: MVATNRCCVFALLFALLLVHSLTEAGKGKEILGKIKEKIIEAKDKMKAGWERLTSQSEYACPAIDKFCEDHCAAKKAVGKCDDFKCKCIKL
What is the function of this protein?
Blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Potassium channel toxin TstKMK, Toxin 5536, beta-Ktx.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IDI_RUEPO
Sequence: MGILIPAWVDDRLVPVDKLEAHEKGLKHKAVSVFAVRDMDILIQRRALGKYHTPGLWANTCCTHPDWDESASTCAVRRLREELGITGLYPEYRHRLEYHADVGNGMVENEVVDVFLAHVRGPLQVVPNPDEVMEIRWIGYHDLLAEVQRYPERFTPWLKIYLHHHADTIFGPDLIISAKA
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXYR_MYCLE
Sequence: MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA
What is the function of this protein?
Required for the induction the katG gene for catalase.  Involved in the response to hydrogen peroxide (By similarity).
What are the official names of this protein?
Probable hydrogen peroxide-inducible genes activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RL7_DESAP
Sequence: MSKVNEIIEIVKGLTVLELAELVKAMEEEFGVSAAAPVAAVAAVPAAAAPVVEEEEQTEFDVILKNVGNEKIKVIKVVREITGLGLKEAKELVDGAPNPVKEKVNKEEAETIKKKLEEVGAGIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TRM3_HHV7J
Sequence: MLRSCDIDAIQKAYQSIIWKHEQDVKISSTFPNSAIFCQKRFIILTPELGFTHAYCRHVKPLYLFCDRQRHVKSKIAICDPLNCALSKLKFTAIIEKNTEVQYQKHLELQTSFYRNPMFLQIEKFIQDFQRWICGDFENTNKKERIKLEPFQKSILIHIIFFISVTKLPTLANHVLDYLKYKFDIEFINESSVNILKQKASVFLVPRRHGKTWFMIPVICFLLKNLEGISIGYVAHQKHVSHFVMKDVEFKCRRFFPQKNITCQDNVITIEHETIKSTALFASCYNTHSIRGQSFNLLIVDESHFIKKDAFSTILGFLPQSSTKIIFISSTNSGNHSTSFLTKLSNSPFEMLTVVSYVCEDHVHILNDRGNATTCACYRLHKPKFISINADVKKTADLFLEGAFKHEIMGGSLCNVVNDTLITEQGLIEFDLFRYSTISKQIIPFLGKELYIYIDPAYTINRRASGTGVAAIGTYGDQYIIYGMEHYFLESLLSNSDASIAECASHMILAVLELHPFFTELKIIIEGNSNQSSAVKIACILKQTISVIRYKHITFFHTLDQSQIAQPFYLLGREKRLAVEYFISNFNSGYIKASQELISFTIKITYDPIEYVIEQIKNLHQININEHVTYNAKKQTCSDDLLISIIMAIYMCHEGKQTSFKEI
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: GM_HCMVA
Sequence: MAPSHVDKVNTRTWSASIVFMVLTFVNVSVHLVLSNFPHLGYPCVYYHVVDFERLNMSAYNVMHLHTPMLFLDSVQLVCYAVFMQLVFLAVTIYYLVCWIKISMRKDKGMSLNQSTRDISYMGDSLTAFLFILSMDTFQLFTLTMSFRLPSMIAFMAAVHFFCLTIFNVSMVTQYRSYKRSLFFFSRLHPKLKGTVQFRTLIVNLVEVALGFNTTVVAMALCYGFGNNFFVRTGHMVLAVFVVYAIISIIYFLLIEAVFFQYVKVQFGYHLGAFFGLCGLIYPIVQYDTFLSNEYRTGISWSFGMLFFIWAMFTTCRAVRYFRGRGSGSVKYQALATASGEEVAVLSHHDSLESRRLREEEDDDDDEDFEDA
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: PSB2_AERPE
Sequence: MAEWIAGGLEGPAGRGLDERVVRSGTTTVGLIASDHVILAADKRATAGFLIASRRVKKIVMLSNYVAMTVSGLVADAQILSDVLREEIRLYEMTNKVKPSVRFVASLLSNILFSSKFFPYIVQLIVGGYDTQPRLYTLDLFGSITEDKYTATGSGSPIAYGVLEERYREDLSVEEAIKVATTAIRSAVLRDAASGDGADVVVIGPQGYEEKFIPYNSLV
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_PSECP
Sequence: MANIDFSAEIRALRATYESIERVTDMEALREDIAELSERAGEPDLWDDPAAAQKITSRLSHRQSELERLTTLASRIDDLEVLVELGQDEGDADSMGEAAAELESIQKALKNLEVVTLLSGEYDEREAVVSIRAGAGGVDAADFAEMLMRMYLRWAERHGYPTTVMDTSYAEEAGLKSATFEVKAPYAFGTLSVEAGTHRLVRISPFDNQGRRQTSFAAVEVIPLIEQTDSIDIPDNEIRVDVFRSSGPGGQSVNTTDSAVRLTHIPTGVVVSMQNEKSQLQNRAAAMRVLQSRLLLLKKEQEDAEKKALAGDVKASWGDQMRSYVLNPYQMVKDLRTEHEVGNTSAVFDGEIDDFIDAGIRWRTDNRNAEK
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.