PharMolix/UniProtQA huggingface dataset:
Protein: SHH_DEVDE
Sequence: YGRRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTVMNHWPGVKLRVTEGWDEDGHHFEESLHYEGRAVDITTSDRDKSKYGTLSRLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.  Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes.  Displays floor plate-inducing activity.  Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes.  In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Sonic hedgehog protein C-product: Secreted, extracellular space. Sonic hedgehog protein N-product: Cell membrane; Lipid-anchor. The C-terminal peptide diffuses from the cell, while the N-product either remains associated with lipid rafts at the cell surface, or forms freely diffusible active multimers with its hydrophobic lipid-modified N- and C-termini buried inside.
Protein: CML30_ORYSJ
Sequence: MAPLLLLFLLGGLCALFSLASSSPATKKCGDAKKRREEEGEEVVVVAKKRPEEEPRRPDPDADLGIVFSTFDHDGDGFITAAELEESLKRLGIAVSSAAEAAALVARVDANSDGLIDIHEFRELYDSIPKRRKSHQQHPLPSTAAADEEAAAADEEYEAEEEERDLREAFDVFDGNKDGLISAEELGTVLESLGLRQHGGRPAVAECRDMIRLVDSDGDGMVSFEEFKRMMTVVKA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML30, Calmodulin-like protein 30.
Protein: DPO3E_RICFE
Sequence: MSSLREIILDTETTGLDPRQGHRIVEIGAIEMVNKVLTGRNFHFYINPERDMPFDAYRIHGISGEFLKDKPLFHTIADDFLEFISDSKLIIHNAPFDIKFLNHELSLLKRAEIKLLELSNAIDTLVMARSMFPGSKYNLDALCKRFKVDNSGRQLHGALKDAALLAEVYVELTGGRQSAFKMVDKSVETNNLATNQVNNKTEQATIVIKPTKEELQKHKEFLSSILKTA
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).
What are the official names of this protein?
DNA polymerase III subunit epsilon.
Protein: KUP2_AGRFC
Sequence: MTSSNSTVPDSRSETKKFLVLLLGSIGVVYGDIGTSPLYAFRESLRPFTANGVQHEHVVGLISLMIWTLTIIVTFKYVLFLLRADNDGEGGTLSLLALLMKKTGSYMPVLFFAGLIGSALFIGDAMITPALSVMSALEGMKLVTPAFSDYVLPLSALIMVGLFAVQSKGTGAVAVFFGPITVVWFLAMAWGGLIHIGDDWTILEAVNPINALWFITHAGWAGLIVLGAVFLTVTGAEALYADLGHFGRKPISVAWFILVFPALALNYLGQGALVLSNPAAIENPFYLLYPEWALFPMIILATMATVIASQAVITGAFSLARQAVHLGFLPKLMIRFTSETNTGQIYVPAVNMVLFIGVLVLIFSFGDSESLATAYGISVTGAMVVTTLMAFQFLRSIRGKSAFTAAILLAPLFSIEAVFLAANLLKVHDGGWVPLALAGVIILVMWTWTKGSRYLREKISKNDVSLDTFITSLERSISRESRSAPVLVSGTAVFLTSVPDKAPSVLLHNLKHNHVLHEQNVILTIWTHDKPYVADTDRVEITRISKHFMRLDINFGFMDDPNVVKALPLCKKKGFKFEIMQTSFYLGRRNLIATPNTGLPRWQEDLYIALADFGVDPSAYFKLPPNRVIEIGEQVAI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_CHRVO
Sequence: MIQMQTMLEVADNTGARHVQCIKVLGGSKRRYASVGDIIKVSIKDAAPRGRVKKGDVYNAVVVRTAKGVRRPDGSLIKFDSNAAVLLNNKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RS7_MAGSA
Sequence: MSRRHAAEKREITPDAKFHDYVVAKFMNCLMLDGKKSAAEAIVYGALDKIQAKTGQDPLKVFHEALDNVKPALEVRSRRVGGATYQVPVEVRSDRRQALAIRWLIDYSRKRSETTMIDRLSGELLDAANNRGAAVKKREDTHRMAEANKAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SLIP_HUMAN
Sequence: MAETKDVFGQEPHPVEDDLYKERTRKRRKSDRDQRFRAFPSMEQSALKEYEKLESRTRRVLSNTYQKLIQSVFLDDSIPNGVKYLINRLLALIEKPTVDPIYIALFGSTGAGKSSLINAIIQQAMFLPVSGESICTSCIVQVSSGCCVQYEAKIHLLSDQEWREELKNLTKLLHRTEELSREEADAWNRDEAVEEATWKLQMIYGNGAESKNYEELLRAKPKRKIPTSRVITLKAEEAEELSIKLDPYIRTQRRDWDGEAAEMRIWPLIKHVEVTLPKSDLIPEGVVLVDIPGTGDFNSKRDEMWKKTIDKCSVIWVISDIERVSGGQAHEDLLNESIKACQRGFCRDVALVVTKMDKLHLPEYLRERKAGNQAIQSQREAVLERNEMIKLQRTRILKEKLKRKLPADFKVLEASDLVYTVSAQEYWQQALLTEEETEIPKLREYIRKSLLDKKKRTVTKYVTEAFGLLLLTDSFNSTQNLPNEHLHMSVLRRFAEEKVELLEKAIAQCFACMEQPLQEGVRTARTSYRCILRACLVRSKGNQGFHQTLKAVCLKNGIYASRTLARIDLNEALTQPVYDQIDPVFGSIFRTGKPTGSALMPHIDAFKQSLQEKMTEIGIRSGWKYDSCKKNFLIQEISAILGGLEDHILRRKRRIYESLTASVQSDLKLCYEEAAQITGKKACERMKDAIRRGVDRQVAEGMFERAQERMQHQFQQLKTGIVEKVKGSITTMLALASSQGDGLYKELADVGSEYKEMEKLHRSLREVAENARLRKGMQEFLLRASPSKAGPPGTSL
What is the function of this protein?
Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146).  Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).
What are the official names of this protein?
Nuclear GTPase SLIP-GC, Speckled-like pattern in the germinal center.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: RGTA_RHIL3
Sequence: MLERATRTIKTAGLLLAAYFVLNIVLRIVLPHSLELDEAEQSFFSQYLLAGYGPQPPFYNWMQYAVVSVTGISIGALIVPKNILLFLSYLFYGLAGRRVLKDEALAAVGMLALITLPQVSYMAQQDLTHTTALLFASSLFLYGFFRTLDRPDMASYLLLGLATGIGLISKYNFALMPVVALIAILPDAEWRRRALDWRMLAAITVALVIVLPHAVWLQGNLAFASSDTLVKMAAGSEPAGAVRIGKGLLAFLVAIIAFAALPVVIFAATFRRDFVRALSAGNRWTGMMERMMLASLAGIALIVLFTGSTTVRERWLDPFLLVLPIYFLAKMQAAGLDLSAGLRRFRPVLPVLMACVLIALGFRVVGAGLIGTYSRPNVPMAGFAREMTRQAEPALVIASDTYIGGNMRLQFPDVPVVIPDFPAPGIPAYAEAKGPVLIVWRGKKTATAADAVMPERFSSALTAAGIALQEIGSLSLPYYFGRQGDNFALGYAWVRPETR
What is the function of this protein?
Involved in the modification of the lipopolysaccharide (LPS) inner core.  Catalyzes the transfer of a galacturonic acid (GalA) residue to the 4-position of the outer Kdo (3-deoxy-D-manno-octulosonic acid) residue of the LPS inner core, using dodecaprenyl phosphate-GalA as the donor substrate.  GalA addition by RgtA is required for RgtB activity.
What are the official names of this protein?
Lipopolysaccharide core galacturonosyltransferase RgtA, LPS core GalA transferase RgtA, Dodecaprenyl phosphate-beta-galacturonate:lipopolysaccharide core alpha-galacturonosyltransferase RgtA, Dodecaprenyl-P-GalA:LPS core galacturonosyltransferase RgtA, Galacturonic acid transferase RgtA, GalAT RgtA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYC_RUBXD
Sequence: MSVKVRDSLSGGLVEVGGDGRVGIYVCGPTVYNHIHIGNVRGHLFWDVAVRFLRSRGYRVKFVWNITDIDDKIINRANEEGVSWKEIVRRYTDSFHERLRLLGIGMPDVEPRATEHIPEMISLIEELIRRGHAYPAPNGDVYYAVETFPRYGALSKQRPEEMKITEKGQTGHKRNPLDFTLWKASKPGEPSWESPWGPGRPGWHIECSAMVEKHLPGGADIHGGGSDIRFPHHENELAQSCGAHPDRPFVRAWAHHGMVRMAAQKMAKSVGNVVDAREATLKHGRDAIRMWLLQSHYSQPIDYSDEILEEKRRSCERLLRLYREISRSEASSPLSDRLAGELRERFDAAMREDFNTPEAIAALFDAASGAGREISSRPSAAGEFASLKEALQELLGLLGFDVAGERVSEVDGVRIRHAGEAPGEVLERVARRERARRRREWPEADRLREELLREGWAIEDTAAGPVLSRR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SYNS9
Sequence: MAKGGVKKAAAAAARAAANRLMADNRQARHQYEILETLETGIELVGTEVKSIRNGKANLRDGFCLIRNGELQLHNVHISPHSHASAYFNHDPLRTRKLLAHRREIDKLRGQLDKKGLALIPLNIHLKGSWIKITIGVGKGRKLHDKRAADKEKQSKKEVRSAMAKYQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL7_XANOR
Sequence: MSLTNEQIVDAIAEKSLMEVMELVKAIEDKFGVSAAAPVAAAAAAGPAAVVEEQTEFTVVLTNPGLNKVTAIKAVRGVTGLGLKEAKDLTEAGGILKEGVSKDEAEKIKKEMTEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HAS1_ASPTN
Sequence: MGSAQDQTKKRKRQKVSDGSKSSKSRVVEADDQRELTETTTKPKKQKTEDPPTDETPDAEDVEQTENGETAQDDAAKDAEAPLPSTMGLSLPTDAAPQKFDELNLSEPTMKAIRQMGFETMTEIQQRTIPPTLAGRDILGAAKTGSGKTLAFLIPAVEMLSALRFKPRNGTGVIIITPTRELALQIFGVAKELCEFHSQTYGIVIGGANRRAEAEKLNKGVNLLIATPGRLLDHLQNTQGFVYKNCKVLVLDEADRCLDVGFEAELRQIVKILPSEERQTLLFSATQTTKVEDLARISLKPGPLYINVDHRKEHATVDGVDQGYIICEADKRFLLLFTFLKKNLKKKIIIFFSSCNAVKYYADLLNYIDLPVLALHGKLKQQTRTQRFFEFCNATQGTLICTDVAARGLDIPAVDYIIQFDPPDEPKAYIHRVGRTARGTKGKIGRSIMLLQPSEVGFLNVLREARVPVVEFEFPQKKIIDIQSQLEKLIGQNYYLNQIQSAKDGYRAYLHAYASHSLRSVFNINKLDLVKVAKSFGFTTPPRVDITLGASMSKDKVQARRPYGSQNKSARFKRRA
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase has1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RF3_SHISS
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVSRLKSEYSVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMZA_HALSA
Sequence: MRVDIVPVGDVPAHVKRQASSSLRSVYDCEVVVASEQDVPTAAYDEARSQYRAAEFIDTATRATSGDKTIAITPHDLFYRRRNYVFGLAYLDGRGCVVSTYRLQTSSDGGFSNRSSSDVFDDRVRKEVVHELGHTLGLEHCDNNRCAMNFSPTVREVDRKEENLCGSCQRTVF
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: CHI1_CAPAA
Sequence: SIGFDGLNDPDIVAR
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: GPDA_TRYBB
Sequence: MVSGVTYLKRGAVFGSGAFGTALACVLAKKCESVSVWHMNANEARVVNQKHENVYFLPGAPLPANLTFTADAEECAKGAEIVLFVIPTQFLRGFLQKNSHILRNHVVSRNVPVVMCSKGIERSSLLFPAQILEEFLPNYPIGVIAGPSFAIEVAKGMLTNVCTAAADINMARKIQRIMTTSDGSFRCWATTDVIGCEIASAMKNVLAIASGALKGLGTENNARAALISRGLLEIRDLTLALGGTGEAVFGLPGLGDLLLTCSSELSRNFTVGMKLGQGISLEEIKRTSKAVAEGVATAEPLERLAKKHNADLPICHEVYNVLYANGCAKRSFKKLNSCKLADEGLPALPRTSKM
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: TMM94_HUMAN
Sequence: MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEVWRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSAMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPVIDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRFIFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHSSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPYSHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTERLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQMLSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRDRNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF
What are the official names of this protein?
Transmembrane protein 94.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HFE_DICBI
Sequence: MGPRARPALFFLILLRTVAAQGRPPRSHSLRYLFMGASERDHGLPLFEALGYVDDELFVAYNHESRRAESRAQWVLGEAHSQLWLQLTQSLKGWDHMFIVDFWTIMDNHNHSKESHTLQVILGCEVQEDNSTRGFWKYGYDGQDHLEFCPETLDWRAAESRALTTKLEWEVNKIRAKQNRAYLERDCPEQLQWLLELGRGVLDQQVPPLVKVTHHVASAVTTLRCQALNFYPQNITMRWLKDRKPVDVKDAESKDVLPSGDGTYQSWEALAVPPGEEQRYTCQVEHPGLDQPLTATWEPSLSNTLVTGVISGIAVCVIIFFIGILFRILRKRQASRGAMGDYVLAECE
What is the function of this protein?
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
What are the official names of this protein?
Hereditary hemochromatosis protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SUCC_ROSCS
Sequence: MKLHEYQARDILARYGVPVTGGGVATTPAEARAIAEQIGGRVVVKAQVFVGGRGKAGGVKLADTPEQAEQVAGQILGMNIKGLTVEKVLVAEAITYEREIYLGAIMDRASRRIVMMASAEGGVEIEEVARTNPEAIVKVAAHPMLGLLDFQARDLAYGIGLTDAKQARQFAQIATALYRAYMDVDASLAEINPLVVRADGSLQALDSKIVLDDSGLFRHPDLEAMRDASDEPEAEQRAREAGITYIKLDGDIGCMVNGAGLAMATMDVIKLYGGEPANFLDIGGGASKEKVKTALQIILSDPNVKAVMFNIFGGITRVDEVAKGIVAALSEVQTNVPMIARLVGTNEEEGRRILAESALIPAATLAEAAEKAVHAARAG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y1207_STAEQ
Sequence: MDNKDNRKFYLIREDVLPESVIKTLKVKDALKNNSNLSIYDAVKQFNLSRSAFYKYRETIFPVDEKILDQREFTLILYVNDIVGMLAQVLNAISQLQLSVLTIHQSVPIEDKATITLSLNARNSNLSIDEVIESLREINHVTKVDLISMTM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SERP1207.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: Y1166_MYCLE
Sequence: MPPVCGRRCSRTGEVRRYPGSFVRKWKRVETANGPRFRSVVAPHEVALLKHLVGALLGLLNERESSSPLDELEVITGIKAGNAQRPEDPTLRRLLPDFYTPDDKDQLDPAALDAVDSLNAALRSLHEPEIVDAKRSAAQQLLDTLPESDGRLELTEASANAWIAAVNDLRLALGVILEIDRPAPERVPAGHPLSVHFDVYQWLTVLQEYLVLALMAT
What are the official names of this protein?
Uncharacterized protein ML1166.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1332.
Protein: RK32_EUGLO
Sequence: MAVPKKKMSHSKSNSRKSNWKRKVIKKINFAVTLGKSLSFGKLSKFYLDD
What are the official names of this protein?
50S ribosomal protein L32, plastid.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid.
Protein: NFU1_DROME
Sequence: MSKFLSQAALNTLRNTRLGSRQLVRSFKGISNTRNHRIPAHQESGCGHSVGCGLLELRMPVACRRSMFIQTQDTPNPESLKFLPGVDVLGKGNTYDFPNGTTAHNSPLAKLLFRVEGVKGVFFGADFVTISKQEGAEWSLIKPEVFAVIMDFFASGLPVLNDAQPNADTEILEDDDETVMMIKELLDTRIRPTVQEDGGDIVFMGYEGGVVKLKMQGSCSSCPSSIVTLKNGVQNMLQFYIPEVESVEQVFDEADRMIESEFERFEKNLKTLKQQEPSGGGPH
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.
What are the official names of this protein?
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KBX2_LIOAU
Sequence: MAKHLIVMFLVIMVISSLVDCAKKPFVQRVKNAASKAYNKLKGLAMQSQYGCPIISNMCEDHCRRKKMEGQCDLLDCVCS
What is the function of this protein?
Amphipathic peptide that causes significant antimicrobial activity in the growth inhibition assay against E. coli.  Causes paralysis or death to crickets within 48 hours after injection at a dose of 1. 3 ug/insect (26 ug/g of body weight).
What are the official names of this protein?
Beta-KTx-like peptide LaIT2.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GL12_ARATH
Sequence: MKGLVQFLVAKIILLVLASTFVHCYDPNPLQDYCVATNGTNRVFVNGKFCKDPKLVTANDFFYSGLNIPGNTSNRLGASVTDVDVRRIPGLNTLGIAIARLDFAPGGQLPPHIHPRASQIILVLKGQLSVGFVSSNDYNYTLFSKILYPGDVFAFPIGLVQFHANTGKTHAVAIGVVGSQDPGVIPIGDAVFGSNPLIDPKLLAKAFALDVNIVRHVQRVFSSEGYIVK
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Putative germin-like protein subfamily 1 member 2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: DAPE_ACIAC
Sequence: MSRTLILAEQLISRPSVTPEDAGCLELLAGRLAPLGFTCERMDSGPDSFRVSNLWARRAAAGGGAPARTLVFAGHTDVVPTGPPEQWSSPPFTPSHRDGRLYGRGASDMKTSIAAFVVAVEEFLAATPEPAIALAFLLTSDEEGPSVDGTKVVVEQLAARGETLDWCIVGEPTSVRKTGDMIKNGRRGTLSGKLTVRGIQGHIAYPQLARNPIHQALPALAELAATEWDRGNDFFPPTSWQISNIHGGTGATNVIPGTVVVDFNFRFCTESTAEGLKTRVHNLLDRHGLEYDLTWTLGGQPFLTTPGELVAAVQQAITDETGITTELSTTGGTSDGRFIARVCPQVIELGPPNATIHKIDEHVVIADVEPLKNIYRRTLERLNAQAAAA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MEND_BACCZ
Sequence: MNNHIEALSYYLGAFVDELTRLNVCDVVISPGSRSTPIALLMEQHEGMNTYLHVDERSAGFFALGIAKAKKRPVALLCTSGTAAANYYPAVCEAFHSRVPLIVLTADRPHELRDVGAPQAMNQFNLYGTFVKQFTEMALPEASEAMYHYARMTTQRMIASACLAPQGPVHLNFPVREPLIPDFSLESLWDKGRGEYTGVVQQGNVVMPSEYVDSLVGRLSHMEKGLIICGDDSHSEIAAFATQLAEKTGYPILADPLSNIRSGHHDKTMVIDCYDTFLRNELLKETWKPDVLIRFGGMPVSKALTQFIKKQTKAVHIVVDESGQWRDPALVATEVVQASDIAFCSALIEKMPVMKKNDWFRMWQHINEKTKETLREMETYDTAFEGRVITDIVRVLPEGATLFASNSMPIRDTDSFFFTSDKNIQVMANRGVNGIDGIISTALGASIICDPLVLVIGDLSFYHDLNGLLAAKLHELNITIVVVNNDGGGIFSFLPQYEKKEHFESLFGTPIGLDYEHVVTMYGGSFSRVNGWEQFREEVQKGATTEGLHVVEICTNRDENLTLHRTLWAKTQDVITTSLQGESK
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: NOX_RHOER
Sequence: MTTAPTPSIFEPARLGPLTLRNRIVKAATFEGVMPRGAVSDDLINFHAEVARGGAAMTTVAYCAVSPGGRVHRDTLVMDERALPGLRRLTDAVHAEGALAAAQIGHAGLVANTLSNKTKTLAPSTRLSPPAMGLVKGATLAELDGVVSDFERTARVAVDAGFDAIEVHLGHNYLLSSFMSPNLNKRHDRYGGSVAKRAEYPRRVIEAVRVAAGSSVAVTAKFNMSDGVPKGLWLDQSLPIAQILEADGHLDAMQLTGGSSLLNGMYFFRGEVPLAEFVASQPKLVGYGLKFYGPKIFPTYPFEEGFFLPFARQFRQALRMPLILLGGINRVDTIEHALDEGFEFVAMARALLRDPQLVNKFQAESVDQGLCIHCNKCMPTIYTGTRCVVRDALVVREAPRLGQ
What is the function of this protein?
Involved in the degradation of the organic disulfide 4,4'-dithiodibutyric acid (DTDB).  Catalyzes the initial cleavage of DTDB into 2 molecules of 4-mercaptobutyric acid (4MB) (PubMed:26407888, PubMed:27564089).  Low activities are observed with other disulfide compounds, such as 3,3'-dithiodipropionic acid DTDP, 3,3'-thiodipropionic acid TDP and DTNB (PubMed:27564089).
What are the official names of this protein?
4,4'-dithiodibutanoate disulfide reductase, NADH:flavin oxidoreductase Nox.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.