PharMolix/UniProtQA huggingface dataset:
Protein: FCSA_DICDI
Sequence: MSSLSTKTDLLGDPDFIRLQSVEVDGSEVIPGETRPRRNTKFPKLTNSPDGKTFTLYDVYRINKDSDSNFLGIRELLADGKRGDYKWISYKQACIRANNIGSALVQLGLNKGDRIGIFSINRPEWVLSDMAAMNHSLVPVALYATLGANAIEYVVNHSEISVLLCEGKNVEKILSMPGTTIKTIVSYDPLPQATLDKFKDNENVKLYLLSDFEKLGEQNPAQHEVPSPEDLCTLLYTSGSTGNPKGVMLTHTNMVSEVAGANFSPAGVIPEDVHMSYLPLAHSFERAVVSLMCYVGGQIGFFSGLIPELFNDIQVLRPTFLCGAPRVWQRLHDKLWFTVNNDSWLKKFLFNWGLNSKQSALRLGSTTPIWDKLVFSKTKDRLGGRVKFILSGSAPLDPKLAEFLRACFCCPVVSGYGLSENVGGASVAYPEDNNVGHVGPPLSACEMKLIDVPEMNYFSTDKPCPRGEVCIRGFNVFKGYFKDPEKTKEDLKEDGWFHTGDIGRWNENGTLSIIDRKKNIFKLSQGEYVAAEYLESVFVRSPFASQVFVYGDSLNSFLVGVVVPDFEVVQKLFASKYPELDVSNHATLAKSKELYKEILSSFDACAAEAKLHGFEKLKHIYVEHEPFTEENNLLTPSFKPKRPQLKERYQTIIDTLYAEYKRDHPDV
What is the function of this protein?
Long chain fatty acid acyl-CoA synthetases catalyze the formation of a thiester bond between a free fatty acid and coenzyme A during fatty acid metabolic process.  May mediate fatty acid retrieval from the lumen of endosomes into the cytoplasm.
What are the official names of this protein?
Fatty acyl-CoA synthetase A, Long chain fatty acyl coenzyme A-synthetase 1, LC-FACS 1, Long-chain-fatty-acid--CoA synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with endosomes a few minutes after their formation, remains bound through the acidic phase of endocytic maturation and dissociates early in the phase where the endosomal content is neutralized prior to exocytosis.
Protein: EXPA2_ORYSJ
Sequence: MASRSSALLLLFSAFCFLARRAAADYGSWQSAHATFYGGGDASGTMGGACGYGNLYSTGYGTNTAALSTVLFNDGAACGSCYELRCDNDGQWCLPGSVTVTATNLCPPNYALPNDDGGWCNPPRPHFDMAEPAFLQIGVYRAGIVPVSYRRVPCVKKGGIRFTINGHSYFNLVLVTNVAGPGDVQSVSIKGSSTGWQPMSRNWGQNWQSNSYLDGQSLSFQVAVSDGRTVTSNNVVPAGWQFGQTFEGGQF
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A2, Alpha-expansin-2, OsEXP2, OsEXPA2, OsaEXPa1.23, RiExB, RiExC.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: TRSF_DROER
Sequence: MKMDADSSCGADHRDSHGSRSRSRREREQHGRTSNRDSKKKEHKVPYFADEVREQDRVRRLRKRSPRSTRRSASRSQSSDRRHRHRSRSRNRSRSRSSERRRRQRSPRRYNPPPKIINYYLQVPPQDFYGMSGMQQRFGYQRLPHPPPFPPAPYRFRQRPPFLGAPRFGYRNAWRPPY
What is the function of this protein?
Member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl.  Activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins.
What are the official names of this protein?
Female-specific protein transformer.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled subnuclear compartment.
Protein: KPYK_GEOSE
Sequence: MKRKTKIVCTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAAKRTGRTVAILLDTKGPEIRTHNMENGAIELKEGSKLVISMSEVLGTPEKISVTYPSLIDDVSVGAKILLDDGLISLEVNAVDKQAGEIVTTVLNGGVLKNKKGVNVPGVKVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEAHDALHIQIIAKIENEEGVANIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQIALRTEQALEHRDILSQRTKESQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAVTSNEAVSRRLALVWGVYTKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISDLLAKGQGIGRKSAFGKAVVAKTAEEARQKMVDGGILVTVSTDADMMPAIEKAAAIITEEGGLTSHAAVVGLSLGIPVIVGVENATTLFKDGQEITVDGGFGAVYRGHASVL
What is the function of this protein?
Catalyzes the phosphoryl transfer from phosphoenolpyruvate (PEP) to ADP to form pyruvate and ATP (PubMed:3711058, PubMed:15749828).  Has a broad specificity for nucleoside diphosphates and can use ADP, GDP, IDP and UDP (PubMed:3711058).
What are the official names of this protein?
Pyruvate kinase, PK, ATP:pyruvate 2-O-phosphotransferase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: RS4_ANAMM
Sequence: MVAVVERKYRASRRLGVNLWGRSKDPVATRNYPSGQHGSMGYKKLSSFGRQFAAHQKFKCYYAMSSKQLTNTFLRAYNRKGDTGDNLVGALESRLAVVVYSAGFVPTVFSARQLVSHKHVTVNGKVVNIPSFSVKPGDVVQIRERATELPMVLAAIQSQERRVPDHLEVDTAQRSARYLRVPKYCEVPYPANMEVNLVVEFFSG
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DPO3B_TREPA
Sequence: MKILCEKEAFLKEISTAQEVISNKKNTSIFSNVLLAAQGALLTIRATDTKVTFETSIPVNVLAEGTTTVFCDKLVNVVSALPTKEIELTLCEEQLVITPPNKKISFQLRTLSHESFPCFPQNEGGVSLAVPTSDLRNMINHTVFAVSEDSTRHFINGVHVDFQYGNIICVSTDGKRLAYIEKKGESSPQSFSGVIVPTKILGIVNRKLTPEGSVTLCITSQHVYFFFGGYKFSSVLIEGQFPNYKRVIPDHQERSFCVGRVELMEALKRVSLLVEQKSHRIFITIQQGLLTLSSKAHTQENEIGDAQEEIACAYTGESEVIALNYLYLEEPLKVFTSKEVQVEFTDPAKALTLRAVPNTDCFHIIMPMQTE
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECPA_ECO5E
Sequence: MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSIISGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Major subunit of the fimbria (By similarity).
What are the official names of this protein?
Common pilus major fimbrillin subunit EcpA, MatB fimbrillin.
What is the protein family that this protein belongs to?
Belongs to the EcpA/MatB fimbrillin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: NS3B_CVPFS
Sequence: MIGGLFLNTLSFVIVSNHSIVNNTANVHHIQQERVIVQQHQVVSAITQNYYPEFSIAVLFVSFLALYRSTNFKTCVGILMFKILSMTLLGPMLIAYGYYIDGIVTTTVLSLRFAYLAYFWYVNSRFEFILYNTTTLMFVHGRAAPFKRSSHSSIYVTLYGGINYMFVNDLTLHFVDPMLVSIAIRGLAHADLTVVRAVELLNGDFIYVFSQEPVVGVYNAAFSQAVLNEIDLKEEEGDRTYDVS
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b, Non-structural protein 3-1, X2b protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses NS3b protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: VANR_VIBAN
Sequence: MYKILRLIQENQQITSHDDLENVLNGLNNLIGHEFFLFGLSFQPTLKTSETLVTDNYPNSWRQQYDESGFMHIDPIVKYSITNFLPIRWDDAKRVNNDGRVIFEEARCNGLKAGFSIPIHGLRGEFGMISFATSDTKSYDLNQQSIHTSQLIVPLLAHNIGNITRYHKDAKPRAVLTAREVQCLAWAAEGKSAWEIATIINTSERTVKFHFSNACKKLGATNRYQAITKAILGGYINPYL
What is the function of this protein?
Probable transcriptional activator.  Binds to autoinducer molecule ODHL.
What are the official names of this protein?
Transcriptional activator protein VanR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: GUAA_LACE2
Sequence: MDQEKVIVIDFGGQYNQLVARRVRECNVYCEIYSYKTDLAQIKAMNPKGIILTGGPNSCYEDGAPTCTKELFELGVPVLGLCYGAQLMQHVLGGKVEKAPVREYGKTETFVDKSSALFSDVSEKTIVWMSHFDYISQIAPGFKIVAHTADCPVAAAECTEKNLYAIQFHPEVLHTQEGTKMLHNFVRGVCGCAGTWKMDAFVENTIKEIREKVGSGKVLLALSGGVDSSVAAGLLSRAIGKQLTCVFVDHGLLRKDEGDEVESVFGPEGQFDLNFIRVNAQERYYSKLAGVTEPEAKRKIIGEEFIRVFEEEAKKIGAVDFLAQGTIYPDVVESGLGGESAVIKSHHNVGGLPDFVDFKEIIEPLRNLFKDEVRKAGLELGIPEHLVFRQPFPGPGLGIRIIGEVTADKVRIVQDADFIYRSEVDKAVAEYKKANGKAPAWMPNQYFAALTNMRSVGVMGDERTYDYAVALRAVNTIDFMTAESAEIPFEVLQTVMSRIINEVRGVNRVFYDLTSKPPGTIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ARGE_ECO7I
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_NITEU
Sequence: MRTDYCGAINTRHLDKTITLCGWVHRRRDHGGVIFIDLRDREGIVQIVCDPDNVAAFQIAEKIRSEFVLAITGTVRHRPEGTVNHGILSGEIEVLVNAIEILNPSLTPPFQMDDDNLSEAIRLEYRYLDLRRPVMQRNIRLRHQVTMAVRIFLDQHGFIDVETPMLTKSTPEGARDYLVPSRVNAGHFFALPQSPQLFKQLLMVSGFDRYYQITRCFRDEDLRADRQPEFTQIDIETSFLPENEIMGMMEDMIRRLFASVLDISLPDPFPRLSYADAMFLYGSDKPDLRVPLVLTELTDLMQDVPFQVFRDAAQKAGGRVAALRVPGGGELSRKEIDEYTQFVGIYGAKGLAYIKINDLTKGIEGLQSPILKFLPESVVQSILERTQAQNGDLVFFGADKAKVVNDALGALRVKIGHERNLATDSWQPLWVVDFPMFEWDEEEKRWQALHHPFTSPSQGHEDFLTSDPGKALSRAYDMVLNGMEIGGGSIRIHRQDIQSKVFQALNISDDEAKLKFGFLLDALQYGAPPHGGIAFGLDRIVAMMTGADSIRDVIAFPKTQRAQCLLTQAPGAVEEKQLRELHIRLRRTENTNN
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_MYXXD
Sequence: MDNARFEDQLAAGCRALGVTVAADLGPRLQRLMSELLKWNAKVNLTAITAPEEVLEKHFLDSLAVLPEVTGAATLLDLGAGAGFPGLPLKLALPALGVTLVDTVGKKVAFIKAAAASLGLQGVRGLHARAEGQPETEGIPRAEVLIARAFMDLPDWLALAPAYVEPGGRVVAMLGKPQTDAELAARAAERQLRVVSARAYRLPFSGAERQVAVFAKE
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIC_ECOL6
Sequence: MNKVYSLKYCPVTGGLIVVSELASRVIKKTCRRLTHILLAGIPAVYLYYPQISQAGIVRSDIAYQIYRDFAENKGLFVPGATDIPVYDKDGKLVGRLDKAPMADFSSVSSNGVATLVSPQYIVSVKHNGGYQSVSFGNGKNTYSLVDRNNHSSVDFHAPRLNKLVTEVIPSAITSEGTKANAYKDTERYTAFYRVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQTYNPVNGPLPDYGAPGDSGSPLFAYDEQQKKWVIVAVLRAYAGINGATNWWNVIPTDYLNQVMQDDFDAPVDFVSGLPPLNWTYDKTSGTGTLSQGSKNWTMHGQKDNDLNAGKNLVFSGQNGAIVLKDSVTQGAGYLEFKDSYTVSAESGKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGTVVLNQQADTAGNVQAFSSVNLASGRPTVVLGDARQVNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNAQQKSRLLLDLKAQDTNVSVPIGSISPFGGTGTPGNLYSMILNGQTRFYILKSASYGNTLWGNSLNDPAQWEFVGTDKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVTIPQLPGGRKVILDGSVNLPEGTLSEDSGTLIFQGHPVIHASVSGSAPVSLNQKDWENRQFIMKTLSLKDADFHLSRNASLNSDIKSDNSHITLGSDRVFVDKNDGTGNYVILEEGTSVPDTVNDRSQYEGNITLDHNSTLDIGSRFTGGIEAYDSAVSITSPDVLLTAPGAFAGSSLTVHDGGHLTALNGLFSDGHIQAGKNSKITLSGTPVKDTANQYAPAVYLTDGYDLTGDNATLEITRGAHASGDIHASAASTVTIGSDTPAELASAETTASAFAGSLLEGYNAAFNGAITGGRADVSMHNALWTLGGDSAIHTLTVRNSRISSEGDRTFRTLTVNKLDATGSDFVLRTDLKNADKINVTEKATGSDNSLNVSFMKDPAQGQSLNIPLVTAPAGTSAEMFKAGTRMIGFSRVTPTLHVDTSGGNTKWILDGFKAEADKAAAAKADSFMNAGYKNFMTEVNNLNKRMGDLRDTNGDAGAWARIMSGAGSADGGYSDNYTHVQVGFDKKHELDGVDLFTGVTMTYTDSSADSHAFSGKTKSVGGGLYASALFESGAYIDLIGKYIHHDNDYTGNFAGLGTKHYNTHSWYAGAETGYRYHLTEETFIEPQAELVYGAVSGKTFRWKDGDMDLSMKNRDFSPLIGRTGIELGKTFSGKDWSVTARAGTSWQFDLLNNGETVLRDASGEKRIKGEKDSRMLFNVGMNAQIKDNMRFGLEFEKSAFGKYNVDNAVNANFRYMF
What is the function of this protein?
Involved in virulence of uropathogenic E. coli although it is not known how it contributes to it.  Has no mucinase activity.
What are the official names of this protein?
Serine protease pic autotransporter.
What are the subcellular locations of this protein?
[Serine protease pic autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Serine protease pic]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Serine protease pic translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: RN168_DANRE
Sequence: MPPVSEVDRGPVEESSGGLKRSDCVCPVCLEIFLEPVTLPCMHTFCKPCFLETVDKSNMCCPLCRKRVSTWARLNSRNKTLVNMELWRRIQDAFPSQCERRVQGIDDDEEAVMIPKPRVCQPGELRKEYEDQISKLVEEKRALEEAERRASEEYIQRLLAEEEERLEEERRRREEQQLENDEKLARLLSLELNSGPASESTCNIKPAEATPAKKKPSVGDIEKFLRPVPHRQPSSSDSSPDSSLMANKENILSPPKPLSALSAEDCGKLTVHMLECNGKPSTSSFNPSTSEHTFVFNTPKSSSVKRKSSEIELQSEVDLHSKRPCALLRFDSSSEDSPFLSEVAVHEEALRSRWQQEEEDRRLALRIQKELDRENSVDRRKGSADSYQLRQKNTSVSTTTSPDVEGTKKGSNTTTAKNCTGRRGEEKTEKRLSGTTPGKRPGVKTPVSSTAVSSTVKKGTKQTTLTEMFPNMGS
What is the function of this protein?
E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage.  Acts with ube2n/ubc13 to amplify the rnf8-dependent histone ubiquitination.  Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the rnf8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates.  This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of tp53bp1 and brca1.  Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
What are the official names of this protein?
E3 ubiquitin-protein ligase rnf168, RING finger protein 168, RING-type E3 ubiquitin transferase rnf168.
What is the protein family that this protein belongs to?
Belongs to the RNF168 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to double-strand breaks (DSBs) sites of DNA damage.
Protein: PDK1_HUMAN
Sequence: MRLARLLRGAALAGPGPGLRAAGFSRSFSSDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA
What is the function of this protein?
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2.  This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.  Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia.  Protects cells against apoptosis in response to hypoxia and oxidative stress.
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BEBT_TOBAC
Sequence: MDSKQSSELVFTVRRQKPELIAPAKPTPREIKFLSDIDDQEGLRFQIPVIQFYHKDSSMGRKDPVKVIKKAIAETLVFYYPFAGRLREGNGRKLMVDCTGEGIMFVEADADVTLEQFGDELQPPFPCLEELLYDVPDSAGVLNCPLLLIQVTRLRCGGFIFALRLNHTMSDAPGLVQFMTAVGEMARGASAPSILPVWCRELLNARNPPQVTCTHHEYDEVRDTKGTIIPLDDMVHKSFFFGPSEVSALRRFVPHHLRKCSTFELLTAVLWRCRTMSLKPDPEEEVRALCIVNARSRFNPPLPTGYYGNAFAFPVAVTTAAKLSKNPLGYALELVKKTKSDVTEEYMKSVADLMVLKGRPHFTVVRTFLVSDVTRGGFGEVDFGWGKAVYGGPAKGGVGAIPGVASFYIPFKNKKGENGIVVPICLPGFAMETFVKELDGMLKVDAPLDNSNYAIIRPAL
What is the function of this protein?
Probably involved in the formation of volatile ester benzylbenzoate.
What are the official names of this protein?
Benzyl alcohol O-benzoyltransferase, Benzoyl coenzyme A:benzyl alcohol benzoyl transferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: F16PA_LEPBJ
Sequence: MSVHPTQTLSLSQYLIEEQLKLPQATGDFTALMSHLVYAAKIVSREVRKAGLLENVLGSNETVNVQGETQMKLDEYADKVFNHTLTRSGHLCILGSEEHEETVSVPSGYKIGKYTIAIDPLDGSSNIDANVSIGTIFSVHLRKSPADTPGTLSDLLQKGSGQRAAGYVLYGSSTMLVLCTGKGVSGFTLDPSCGEFILSHPDMQMPETGGIYSINEGNYNYWSDEVKNYIRDIKSIEGGKKPQSGRYIGSLVADFHRNLLKGGIFLYPNDTKSTKYPNGKLRLLYEAAPMAFIAEQAGGMAVTVYGERILDLTPKELHERTTLVVGSKKEVEHFLKFAPKKP
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1L_TREPA
Sequence: MTARELDAYFRSFLNFGPFVSCDVALNGLQVANSGAPVHKVAFAVDACAQSIDAAARAGARMLFVHHGLFWGRIEPLTGMQYRRVQALLTHDIALYAVHLPLDAHPQYGNNAGLAARVGLRQGGPFGFIRGTAVGLWGTVAENTTPSQEAMQQHAACTAPDTHRVTHANAISPSAGLSLQQVVHRLFPAEEQPVRLLPFGKQRIERVGILSGKAGTYLAEAIALDLDLFITGEIEHSCYHTAREHSISVIAGGHYQTETVGLQLVARKLQRDTGIETLFLDIPTGM
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: RR19_CHLAT
Sequence: MARSLKKGPFVADHLLKKIEYLNARREKQVITTWSRGSTIVPIMIGHTIAVYNGREHLPIFVTDQMVGHKLGEFSPTRTFRGHVKSDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NLP11_CAEEL
Sequence: MMSTLALVSLAIFGIAVVCAAPKPATVPVANEEDYLAALYGFEAPGSQFKGAPLQSKRHISPSYDVEIDAGNMRNLLDIGKRSAPMASDYGNQFQMYNRLIDAGKKKRSPAISPAYQFENAFGLSEALERAGRR
What are the official names of this protein?
Neuropeptide-like peptide 11.
Protein: RRF_HELPJ
Sequence: MLQAIYNETKDLMQKSIQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNTRQDANNKVKKLEKDKEISEDESKKAQEQIQKITDEAIKKIDESVKNKEDAILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_MYCSK
Sequence: MAIVGVGIDLVSIPDFAEQVDRPGTVFAETFTPGERRDAADKSSSAARHLAARWAAKEAVIKAWSGSRFAKRPALPEGIHRDIEVVTDMWGRPKVRLTGDIAEHLREATIHVSLTHEGDTAAAVAVIEEP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_AQUAE
Sequence: MDGALLIDKPKGITSTEVVERVKEKLKARKAGHTGTLDPIATGLLIILINKATRFSQFFIGMPKTYRFTVKFGAETDTYDAQGKVVETYEGELNCDKLKEVLNEFRGEILQTPPPFSAKKIKGRRAYELARKGKKVELKPVKITVYSLELLSCNPREKEAEFLAEISSGGYVRSLAYDIGKKLGIGGYMKELRRLKIDEISVEEAVSLEEFLSSENPEEYVLPVDTLFRVIPEVRLNTFEAGKILQGKRILIKNYDYEGLVKIYEDSKFIGIGELKGGVLSPKRLLV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y159_AFV2P
Sequence: MTTPLCYSSPVNTPLSPSLLLLSLLLLLSTICGVLPLSLFCCGIGTGITLFNFDDTSDIIAVDIASAICFIIFCNGFCCCCCSGDPPYASSTTSLAICDGMLSLLRGDPPPVAVTYAPIFIAFCMHNSMSLIESKSGLTAFLTRVTMTSSMLPFSSIIS
What are the official names of this protein?
Putative transmembrane protein ORF159.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RL20_LIGS1
Sequence: MPRVKGGSVTRQRRKKIIKLAKGYRGAKHIQFKVAKQQVMKSYQYAFRDRRKTKSNFRKLWIARINAAARQNDISYSKLMHGLKLANVEVNRKMLADLAITDAAAFTALVDEAKKALAAE
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.