PharMolix/UniProtQA huggingface dataset:
Protein: TCML_STRGA
Sequence: MSAPAPVVVTGLGIVAPNGTGTEEYWAATLAGKSGIDVIQRFDPHGYPVRVGGEVLAFDAAAHLPGRLLPQTDRMTQHALVAAEWALADAGLEPEKQDEYGLGVLTAAGAGGFEFGQREMQKLWGTGPERVSAYQSFAWFYAVNTGQISIRHGMRGHSSVFVTEQAGGLDAAAHAARLLRKGTLNTALTGGCEASLCPWGLVAQIPSGFLSEATDPHDAYLPFDARAAGYVPGEGGAMLVAERADSARERDAATVYGRIAGHASTFDARPGTGRPTGPARAIRLALEEARVAPEDVDVVYADAAGVPALDRAEAEALAEVFGPGAVPVTAPKTMTGRLYAGGAALDVATALLSIRDCVVPPTVGTGAPAPGLGIDLVLHQPRELRVDTALVVARGMGGFNSALVVRRHG
What is the function of this protein?
Involved in the biosynthesis of tetracenomycin C (TCM C) (PubMed:9609708).  Part of a type II polyketide synthase (PKS) that catalyzes the synthesis of tetracenomycin F2 (TCM F2), a precursor of TCM C, from malonyl-CoA (PubMed:8248801, PubMed:9609708).  TcmK and TcmL form a heterodimeric alpha-beta complex that catalyzes the condensation reactions between the growing acyl-enzyme chain and the malonyl-CoA extender units (PubMed:9609708).
What are the official names of this protein?
Tetracenomycin polyketide synthase ketoacyl synthase beta subunit, TCM PKS.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: DRDI_CLOBH
Sequence: MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDKFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKTIGENLITLLKDGVGILTHCNAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCDRIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDINTKTGEDIPIEERNPEEVTSRFGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK
What is the function of this protein?
Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
What are the official names of this protein?
5-deoxyribose 1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.
Protein: RS18_FERNB
Sequence: MPKVRQRRRKVKACKMCEMNVEYVDYKDIRILKDFLNEKGKILPRRLTGNCAKHQRMVKIAIKRARQMALLPYIKY
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y1297_METTP
Sequence: MIREYFRLHQTIATIVARSQEHIEIAKSAIIDSRTQLEEFIAFDPLFQLTLVPYDLPVDNAPPIVKRMCHASSLFHVGPMAAVAGAIAAFAVEAMVEAGADYAVVDNGGDIAIFSDEPLLVGIYAGSSPIKNLALEIHPTGGILGVCSSSGTIGPSISFGCADVATVISRDPAIADAGATALGNAVTPDASLKECFSVVDRDEVIGALIIRGDEMAVWGEVPPIRRARVKYDLITKG
What are the official names of this protein?
UPF0280 protein Mthe_1297.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: OPGD_PSE14
Sequence: MNRRNLLKASMALAAYGSVSASGLYAARALAAAADGEIEHFDFAELQAHAKKLAGKGYVSNKQVLPPVLADMTPLQFNAIRYDPNHSLWKDVHGQLDVHFFHVGMGFKTPVRMYSVDPQNKQAREVHFRHDLFNYESSGIDKNLVKGDLGFAGFKLFKAPEIAINDVVSFLGASYFRAVDSNKQYGLSARGLAIDSYAKRQEEFPDFTKFWFETPDKNATRFVVYALLDSPSATGAYRFDIDCQAGQVVMEIDAHINARTDIQQLGISPMTSMFSCGTHERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPAKPQFSAFADTDPKGFGLVQSDHEFSSYQDTVVWYSRRPSLWVEPITAWGEGEVSLLELPTTGETMDNIVVFWTPKTPVKAGDSMNYGYKLFWSPLPPVSTPLAQVHATRSGMGGFLEGWAPGEHYPKTWARRFAVDFNGGGLDRLPEGTGIEPIVTVTHGKVQDFNILVLPDIKGYRVTFDWVPDSDSVEPVEMRMFIRTGDRTLSETWMYQYFPPAPDRRKYP
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HUGA_APIME
Sequence: MSRPLVITEGMMIGVLLMLAPINALLLGFVQSTPDNNKTVREFNVYWNVPTFMCHKYGLRFEEVSEKYGILQNWMDKFRGEEIAILYDPGMFPALLKDPNGNVVARNGGVPQLGNLTKHLQVFRDHLINQIPDKSFPGVGVIDFESWRPIFRQNWASLQPYKKLSVEVVRREHPFWDDQRVEQEAKRRFEKYGQLFMEETLKAAKRMRPAANWGYYAYPYCYNLTPNQPSAQCEATTMQENDKMSWLFESEDVLLPSVYLRWNLTSGERVGLVGGRVKEALRIARQMTTSRKKVLPYYWYKYQDRRDTDLSRADLEATLRKITDLGADGFIIWGSSDDINTKAKCLQFREYLNNELGPAVKRIALNNNANDRLTVDVSVDQV
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase, Hya, Allergen Api m II, Hyaluronoglucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_SYMTH
Sequence: MSEPTGKILAIMGAVVDVEFPDGHLPKLNHALVIRNGGERGDINLTLEVAQHLGNNQVRCIAMDSTDGLRRGETVYDTQAPITVPVGEPVLGRIFNVLGETIDGKGPVNSPVSLPIHREPPGVANVDPATEMLPTGIKVIDLLCPYARGGKIGLFGGAGVGKTVMIQELIHNIAYKFGGYSIFAGVGERTREGNDLYHEMIEAGVIDKVAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGLDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGYLQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAVFEKAIFPAVDPLDSTSRILDPNIVGREHYEVARGVQKVLQRYKELQDIIAILGMDELSDEDKLIVARARKIERFLSQPMFVAEKFTNLPGVFVDPKDTVKGFKEILEGKHDDLPEQAFYMVGTIEQAVEKGKKLLAEVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSP1_SHEEP
Sequence: MARYRCCLTHSRSRCRRRRRRRCRRRRRRFGRRRRRRVCCRRYTVVRCTRQ
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: EX7L_GEOMG
Sequence: MELFPEKRILTVSQLTSLIRGVLEENFEHVWVEGEVSNLAMPASGHLYFTLKDAGAQIRCVMFRASARALKFRPRDGMGLIVRGRITVYEQRGDYQFLVEYLEPRGVGALQLAFIQLKEKLAKEGLFAEEHKRPIPSLPQRIGVVTSATGAAIHDILNVLNRRFANVEVLIRPVKVQGEGAADEIAEAIIDFNRYGAVDVMIVGRGGGSLEDLWAFNEEKVARAVHRSRIPIISAVGHEIDFTIADFVADLRAPTPSAAAELVVKSKEELASKVEFLRHRLIQTLRRILADAGGELESLSRALRDPTVLLGHLSQRLDDIFVRLERAIAGDLKDRGRMLEALKNHLRLRNPALKVERARERVIALSDKSEIALLRHVDRYREAAAVHSARLETLSPLGTLARGYSVALKLPERVPVKTFRQLALKDRLELLFHHGRAWCRVESLDEDASCSHE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_STRE4
Sequence: MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTEMGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLKALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDDKPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_HALS3
Sequence: MVVTVRAPATSANLGSGFDVFGVALSKPADVVRVERADTTTITVTGAGAQYVPTDPQENTAGVVAAALDAPATIHINKGVRPSSGLGSSAASAAAATVALAELYDRPLDDDALVRAAAQGEAAASGVAHADNVAPAILGGFTIVREDGIEHVDASLALAVCLPETTVSTRDARGVVPESAAMEAVVSTVESAATLTLGMCENDPQRVGRGVEDALVTPARARLMDGYEAASAAARDAGATGVTISGSGPGVVAVCRRRDRKRVAAALVDGFDSAGVAASAYQTRIGDGATRLAADGDDRAP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_STRP3
Sequence: MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSYPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: GET1_SCHJY
Sequence: MDFLLFLFCLNLFIHLFDKYVKTFLVNQGFRVYARFSGSPEFKSYNDLRLQLLSTKRDLNNVSAQDEFAKWARLNRKFDQLNVKWEKQSKIVSQKSEGVKKLISLTFWIVTRGYRFIVQFKNSGNPVFAVPEGMLPTWALWFLALPKAKTGYVSVAVWNFASQKVISTLL
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMH_CHLAB
Sequence: MSATPSHIPVLVNECLSLFADRHPKFFCDVTVGAGGHAEAFLSAYPSIVSYDASDRDVAALSMAKEHLEKFGDRVHFHHASFEDLSKDPREHVYDGILADLGVSSMQLDNLSRGFSFQGDDHALDMRMDVTKGITASEVLHTLREEELGKIFREYGEEPQWKNAAKAIVHFRRRKKIVTVRDLKEATAKVFPSYRLRKKIHPLTLIFQALRVYVNQEDVQLKVLLESAMRWLAPGGRLIIISFCSSEDRPVKWFFREAEKSGLGMILTKKVIMPTYEEIRKNPRCRSAKLRCFEKKFL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPIC_HUMAN
Sequence: MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTEEPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
What is the function of this protein?
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis.  Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.  Regulates VCAM1 gene expression (By similarity).
What are the official names of this protein?
Transcription factor Spi-C.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PXPA1_AGRFC
Sequence: MAAIDLNSDLGESYGAWRMGDDEAMLAIVSSANIACGFHAGDPAGIYRTVKAAAEKGVVVGAHVSYPDRVGFGRRDLDATSEELIADVIYQIGALKGVAAAAGTTVRYVKPHGALYNRIANDAKQGQAVIDGIKAIDPSLVLMGLANAPILDLARKAGLAVVAEAFADRAYTPEGQLVSRREAGAVLHDAAKIAERMVQLAREGTLEAIDGSIIKIEAQSICVHGDSPGAVAIAQEIRRRFEADGIAIRSFASDR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A 1, 5-OPase subunit A 1, 5-oxoprolinase (ATP-hydrolyzing) subunit A 1.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: AOX_MONFR
Sequence: MYVARLSTRPLSNPSTAQLSKAAAFFAQSYALPSTKCTAHVPSRRPFTSGAKIQVKGRDLFPEPXHGQIKRTEPAWPHPPYSVEQMRSKVYFAHRKPRDFSDRVALGMVRFLRWCTDFATGYKHNVEAPKTASDSNAVTATKPYQMSERKWLIRYVFLESVAGVPGMVAGMLRHLRSLRGLKRDNGWIETLLEEAYNERMHLLTFLKMYEPGLFMRTMILGAQGVFFNSFFLCYLFSPKTCHRFVGYLEEEAVLTYTLSIQDLENGHLPKWADPNFKAPDLAIEYWGMPEGHRSMRDLLYYIRADEAKHREVNHTLGNLKQDEDPNPFVSVYGKEVADKPGKGIESLRPLGWEREEVI
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial, MfAOX1.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: PSMD1_RAT
Sequence: MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDTQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGPEKDSDSMETEEKTAGAVAGKTPDASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNTQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGVCCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCIIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLSMTETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit S1, 26S proteasome subunit p112.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.
Protein: PYRF_MYCBT
Sequence: MTGFGLRLAEAKARRGPLCLGIDPHPELLRGWDLATTADGLAAFCDICVRAFADFAVVKPQVAFFESYGAAGFAVLERTIAELRAADVLVLADAKRGDIGATMSAYATAWVGDSPLAADAVTASPYLGFGSLRPLLEVAAAHGRGVFVLAATSNPEGAAVQNAAADGRSVAQLVVDQVGAANEAAGPGPGSIGVVVGATAPQAPDLSAFTGPVLVPGVGVQGGRPEALGGLGGAASSQLLPAVAREVLRAGPGVPELRAAGERMRDAVAYLAAV
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: RL10_ACIBY
Sequence: MALLIEDKKQIVAEVSEVASKAFAAVVADYQGLSVEQLTTLRVEARKLGVTTRIVRNTLAKRAFQGTQFDILNDNLVGPTILGFSTSEDDMGAAARLFEEFAKTNKAFELKAAAFDGKVYQGADVSVIANLPNQEKALTMLASVLQAPISKLGRLITALKEKNESEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AAPJ_RHIL3
Sequence: MKNKLLSAAIGAAVLAVGASAASATTLSDVKAKGFVQCGVNTGLTGFAAPDASGNWAGFDVDFCKAVASAVFGDPTKVKYTPTNAKERFTALQSGEIDVLSRNTTWTINRDTALGFNFRPVTYYDGQGFMVRKGLNVKSALELSGAAICVQSGTTTELNLADYFKTNNLQYNPVVFENLPEVNAAYDAGRCDVYTTDQSGLYSLRLTLKNPDEHIILPEIISKEPLGPAVRQGDDQWFDIVSWTAYALINAEEFGITQANVDEMKNSPNPDIKRFLGSETDTKIGTDLGLTNDWAANVIKGVGNYGEIFERNIGQGSPLKIARGLNALWNKGGIQYAPPVR
What is the function of this protein?
Part of the ABC transporter complex AapJQMP involved in uptake of L-amino acids (PubMed:8898392, PubMed:19597156).  Affects the efflux of these amino acids as well (PubMed:8898392).  Essential for the development of bacteroids, the differentiated legume-symbiotic forms of this bacterium, and for the effective N(2) fixation by them (PubMed:19597156).
What are the official names of this protein?
General L-amino acid-binding periplasmic protein AapJ.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS18_MANSM
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: METN_CHLAB
Sequence: MFNQNSPIISVEQLNKEIANHRILHRISFSVYPGEIVGIIGHSGSGKSTLLRCLDFLIEPTSGSISIAGFHTSSPIEKISRTAFAKRVAYVSQSCGLFLAKTVFENIAYPLKIRCPEMTKALIEEKVDDVLHFFNLYERKHAYPSRLSGGQKQKVAIAIAIVSDPRVLLCDEITSALDPRSTEDVVDKLSQLNEERGITQVFVSHEIEIVKKLCCQTLVMHQGSIEESGPTEQLFLNPQSAITEELFHMQSIAKGIYEHGENEEILRLGFPKGLAVQGMISQLIQSGGISINILSGDIHLFRKTPLGFLIVALSGGKEQRDWAKSSLREKGVIVKQFQKSR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALAE_PANSA
Sequence: MALSWQSLIDRITNLAKNQRQKKRGTEFLADTVALILFFTTTGIINERMIAGMSWDQVLHARLIGAALMIPVARPYGIWRDWLMQRANPSRGSQLLWDSMALVSFQVPIYAAIIAFSGATGGGLVRGTLGAALMMLFLGRPYGAFLNWVRKLFGLPPGGDKPMSLDS
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPA_TRIVH
Sequence: MVQISQIGAVLAVCSTLTVAAPTKGKARFNVPQVAVPMKAVHHPAVAYARALHKFGMKVPKAVSDAARGSVPTTPTKDDEQYVTQVTVGQGKLNLDLDTGSGDLWVFSTETPKDQSQGHNLYMPTSKSKRLDGYSWEITYGDMSSAGGDVFLDTVSIGNVTASSQAVESAKKVSDQFAKDKATDGLMGLSFSVLNTVQPKPQTTFFDTVLKQLEKPLFTCTLKHGQPGSYDFGYIDDSKHSGEIAYTNVDNSQGWWGFTAESYSIGGGSNSTHSFHGAQHHGARGSSIDGIADTGTTLMLLSDDVVQEYYKQVQGAKNDQQQGGWVFPCDAKLPDFTLSISGYNAVVPGKFMNYQAVGSVCFGGLQSVGSSGGVPNIFGDVFLKSQFVVWDTEGPRIGFAPQA
What is the function of this protein?
Can catalyze hydrolysis of the major structural proteins of basement membrane, elastin, collagen, and laminin.  Thought to play a significant role in virulence (By similarity).
What are the official names of this protein?
Aspartic endopeptidase PEP1, Aspergillopepsin I.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MYH3_RAT
Sequence: MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDKIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYTPEVVDGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDREELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGKAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATTDADGGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFLMRVEFQKMMQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQQVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYSQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAELAEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARGKNEETQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKADIQMALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLTQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANVHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-3, Myosin heavy chain 3, Myosin heavy chain, fast skeletal muscle, embryonic.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: SMYD1_HUMAN
Sequence: MTIGRMENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFVCHTCFKRQEKLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKVPNENIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLNVSEERKRQLKKQYYFDCTCEHCQKKLKDDLFLGVKDNPKPSQEVVKEMIQFSKDTLEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTNIYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVGHGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEPSNEPSPALFHKKQ
What is the function of this protein?
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation.  Acts as a transcriptional repressor.  Essential for cardiomyocyte differentiation and cardiac morphogenesis.
What are the official names of this protein?
Histone-lysine N-methyltransferase SMYD1, SET and MYND domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRPD_PSEA7
Sequence: MDIKGALNRIVNQLDLTTEEMQAVMRQIMTGRCTDAQIGAFLMGMRMKSETIDEIVGAVAVMRELADGVQLPTLKHVVDVVGTGGDGANIFNVSSAASFVVAAAGGKVAKHGNRAVSGKSGSADLLEAAGIYLELTSEQVARCIDTVGVGFMFAQVHHKAMKYAAGPRRELGLRTLFNMLGPLTNPAGVRHQVVGVFTQELCKPLAEVLKRLGSEHVLVVHSRDGLDEFSLAAATHIAELKDGEVREYEVRPEDFGIKSQTLMGLEVDSPQASLELIRDALGRRKTEAGQKAAELIVMNAGPALYAADLATSLHEGIQLAHDALHTGLAREKMDELVAFTAVYREENAQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.