PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_BURO0
Sequence: MRILGIDPGLRVTGFGVIDVSGHRLAYVTSGVIRTPTADLATRLGTIFQGVSTIVRDHAPDQAAIEKVFVNVNPQSTLLLGQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQDMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLGGLAPALAQKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RPOC_SHEWM
Sequence: MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKMGAEAVLELLRAIDLEKEIDMMREELPSINSETRRKKITKRLKLIEAFFQSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVPEVWDVLDDVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARSLMMSTNNILSPANGEPVITPSQDVVLGLYYTSRECVNGKGEGMAFESIDEVEKAYRTKVAAIHARIKVRVTETQIAENGERTESRRIVDTTVGRALLSRILPKGLSYDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYAGFHYATVSGASVGINDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMANLSSETVINRDGEEEEQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVSQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVIEEDCGTFEGLTMKPLIEGGDVVEPLRERVLGRVVAQDVLKPGTEEVLVPRNTLLDEAWCDIVEENSIDEMIVRSVISCDTDFGVCAACYGRDLARGHIINQGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNLGTLKLHNAKYVTNSVGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEDDAVAAGEIIANWDPHTHPIVSEVAGSIKFVDMIEGVTMTRQTDELTGLSSIVVMEVGQRPSAGKEMRPAICLIGADGNDLMIPGTEVPAQYFLPGNAIVAQDDNAPINVGDALARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEHSGTISFGKETKGKRRLVITPADGGDHYEEMIPKWRNLNVFEGEKVERGEVIADGAEAAHDILRLRGIHKVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCEITNAGDSEFLAGEQAEVSRVKIANRELEAQGKQPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDKLRGLKENVIVGRLIPAGTGYSYHQKRNAETATGTDTEAAPVISASEAEQNLADLLNLAGSSD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CTSR_STAAR
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: CD14_MOUSE
Sequence: MERVLGLLLLLLVHASPAPPEPCELDEESCSCNFSDPKPDWSSAFNCLGAADVELYGGGRSLEYLLKRVDTEADLGQFTDIIKSLSLKRLTVRAARIPSRILFGALRVLGISGLQELTLENLEVTGTAPPPLLEATGPDLNILNLRNVSWATRDAWLAELQQWLKPGLKVLSIAQAHSLNFSCEQVRVFPALSTLDLSDNPELGERGLISALCPLKFPTLQVLALRNAGMETPSGVCSALAAARVQLQGLDLSHNSLRDAAGAPSCDWPSQLNSLNLSFTGLKQVPKGLPAKLSVLDLSYNRLDRNPSPDELPQVGNLSLKGNPFLDSESHSEKFNSGVVTAGAPSSQAVALSGTLALLLGDRLFV
What is the function of this protein?
Coreceptor for bacterial lipopolysaccharide.  In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:16148141).  Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135, PubMed:15895089).  Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (By similarity).  Acts as an accessory receptor for M. tuberculosis lipoproteins LprA, LprG and LpqH, in conjunction with coreceptors TLR2 and TLR1.  The lipoproteins act as agonists to modulate antigen presenting cell functions in response to the pathogen (PubMed:19362712).  Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).
What are the official names of this protein?
Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Membrane raft. Golgi apparatus. Note=Soluble, secreted forms seem to exist. They may arise by cleavage of the GPI anchor.
Protein: AC4CH_KLEP3
Sequence: MQANDITFFQRFQEDILAGRKTITIRDAAESHFKPGDVLRVGRYEDDGYFCTIAVTATSTVTLDTLTEEHARQENMTLEQLRQVIMEIYPAEDRFYVIEFKRL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: RS9_CHLPM
Sequence: MKEVIDTVGRRKTSVARVFMTPGKGRVIINKLPAEEYFKDEVKCRVALRPLVLAEKTEDFDIKVNVHGGGISGQSGAVSLAIARALAETDDSVRAVFKPERLLTRDPRMVERKKFGRKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CHEB2_SHESM
Sequence: MTIKVLVVDDSALIRNLLGQMIEADSELSLVGMAADAYMAKDMVNQHRPDVITLDIEMPKVDGLTFLDRLMKARPTAVVMISSLTEEGADATFNALALGAVDFIPKPKLDSPQDFNEYQDLILEKIKSAAHAKLKTQRAAPAVVVQPSHKPALSSRVINTQLVAIGASTGGTEAILSLLQQFPAVMPPIVITQHMPPGFTRTFAERLNKLTRLNVKQAEDGERLLPCYVYIAPGDQHLEVIKVGGSFKTRLTQGDKVSGHRPSVDVLFNSVAECAGANTTAAILTGMGKDGADGMALIDEQGGKTFAQGEQSCVVFGMPREAIKRGVIHHVVELPQLADKMLNYLASLKRD
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECG_METBU
Sequence: MAQKKKSSGSGLMSSAGLMTYYDADKKAIHVQPKTVFIFGAICGIVILAFSAGFGLWP
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRMA_YERPG
Sequence: MTPNILPIESYDHQLAEKSARLKAMMLPFQAPEPEIFRSPADHYRMRAEFRVWHDEDDLYHIMFDQQTKQRIRVEQFPVASRLINRLMDALMTAIRAEPLLRRKLFQIDYLSTLSGKLIASLLYHRQLDEEWQQKALELRDQLRAQGFDLQLIGRAAKTKIMLDHDYIDEVLPVAGREMIYRQVENSFTQPNAAVNIHMLEWALDVTQGATGDLLELYCGNGNFSLALARNFERVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMQGVREFNRLKGIDLGSYNCETIFVDPPRSGLDHETVKLVQAYPRILYISCNPETLCANLEQLQHTHKISRLALFDQFPYTHHMECGVLLEKRH
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: GATB_CITBB
Sequence: MKYQVVIGLEVHTQLTTNTKIFCGCSTRFGAEPNSQTCPVCLGLPGALPVLNQQVVEYAIRAGLATNCSITKRNVFARKNYFYPDLPKGYQISQFDLPICQHGHLDIEVEGEKKRIGITRIHMEEDAGKLVHADIPGVDDSCVDLNRACTPLLEIVSEPDMRSPDEAIAYLKKLHQIVMYLGICDGNLEEGSFRCDANVSLMPVGSNVFGTRAELKNINSFKFIKQAIEYEIERQAEILDDGGKVVQETRLFDPNTGTTRSMRGKEEAHDYRYFPDPDLVPVIISDDWIEKVRGGLPELPEAKRARFMSEGGAVFGGSAFGLPEYDAEVLVASRELAQYFEDTVALFPQAKTVSNWVMGEVTRALNDDNNRSIAECPVTPALLADLLKLMEKGTISGKIAKTVFDEMYKTGKASEKIVEEKGLVQVSDTGAIEAMVDEVLEKNPGQVAEYRGGKETLFGFFVGQVMRASKGKANPAVVNELLLKKLNS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: YBEY_ANADF
Sequence: MTVRLSSEHPRGRSAARRLRTRAAAYLAALGRADAEISILLVGDRRIRALNREWRGKDAATDVLSFPLSEPPGSGPLLGDVVISLDTAARRARQERRAVGAELDRYLAHGLLHLLGYDHERPADARRMARKEAELARAEGLVGAALREGGPARAAETETSWTRSPTSTSTRSPSGSTARGTRARSSRAGSGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y036_OSHVF
Sequence: MSTTEQTVCEIEQESELIPAKPQYIIVKKPKRQAWQRVLLLFRIINMIVIWAALIALFVKLYILRGPIPRSYFHY
What are the official names of this protein?
Uncharacterized protein ORF36.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y4RG_SINFN
Sequence: MSHAEKPMSDSVNHHHHRTFEVLTAEPVRSRRKPRHWSDEEKAQLVAEALSPGANVSAIARSQGLDPSQLYAWRRKALSSGMVAPLTEGAPAPVKFTRFEAVGSSMVEIVVGDIVVRAGADVDPDHLAKILRVVR
What are the official names of this protein?
Uncharacterized protein y4rG.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: AC4CH_SALPA
Sequence: MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDVLRVGRFEDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: HIS8_SYNP6
Sequence: MLPFLRSELARCQPHHPNPGGTGMAMDILDTNECPYDLPTDLKQTLADRYVEAIASNRYPDGSHTDLKAAIVDYLSEQTAGQWQPGPEHVTVGNGSDELIRSILIATCLGGQGSVLVAEPTFSMYGIVAETLGIPVVRIGRDPQTWEMDLAAAETAITQTEGTPVRLCFVVHPNSPTANPLTEAEKDWLRQVPPQILVVIDEAYFEFSGETLLAELPQHPNWLITRTFSKALRLAAHRVGYGIGDPQLIAALEAIRLPYNLPSVAQLAATLALEARSQLLSAIPRLITERDRLYRKLQVVSQLQVWPSASNFLFLKTQSSSQTAALAAQLKAQGTLVRHTADGLRITIGSPAENERTLAHLQTAITQSLPATV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CH10_RHOPL
Sequence: MAFKPLHDRVLVRRVQSDEKTKGGLIIPDTAKEKPAEGEVVACGEGARKDSGELIAMSVKAGDRVLFGKWSGTEVTIDGAELLIMKESDILGILS
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PROM0
Sequence: MANLKEIRDRIVSVKNTRKITEAMRLVAAAKVRRAQDQVLKSRPFADKLARVLENIQSRVQFEAVDSPLLSKREVKSISLVCITADRGLCGGYNTNIIKKVEIRYAELVKQGYQPNLILVGKKAIGYFQNRKDRYVIKSTFKELEQVPTVKDSEGVTNEILAEFLSENSDRVEIIYTKFITLVSCAPVVQTLLPLDPQGIAEENDEIFRLTTKDSKLLVEKSNIEKSDSEKLPSDIVFEQSPDQLLDSLLPLYLQNQVLRALQESAASELACRMTAMNNASDNAKELASTLNLTYNKARQAAITQEILEVVGGSVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: GVPF1_HALSA
Sequence: MTENLYTYGIIEQEDLELDVEGVAGAEQVYTVDYKTLSAVVSDIDTTDPERTDEDVEAHNNVLQEVLKHEEERTVVPMSFGMAFKSARTLKGVLRGARRALRSTLNDIEGTVELGVKILGPGDDTVPREEIQENVTDQLADLSINETENDLFTDRLIINKSYLVDFEKRDAFDSAIDDVEAEYDELTIQYTGPWPPYNFVDIHIGAEQQQGGR
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpF 1.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: Y775_MYCBP
Sequence: MPRAHDDNWDLASSVGATATMVAAGRALATKDPRGLINDPFAEPLVRAVGLDFFTKLIDGELDIATTGNLSPGRAQAMIDGIAVRTKYFDDYFRTATDGGVRQVVILAAGLDARAYRLPWPAGTVVYEIDQPQVIDFKTTTLAGIGAKPTAIRRTVYIDLRADWPAALQAAGLDSTAPTAWLAEGMLIYLPPDPRTGCSTTAPNSVLRAARSLPNLSRALWISTQAGYEKWRIRFASTAWTSTWRRWCIPANAATSSTTCAPRAGTLRAQCGPTYSGAMVCPFPPHTTTIRSAKSSSSAVV
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase BCG_0775c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: ALAT2_XENTR
Sequence: MDSDLISSRCVWATWNVYNGRSLSGTPLAERDGKVARKMSENGTCNRILTLESMNPCIQKVEYAVRGPIVIRAVELEKELQQGVKKPFTEVIKANIGDAHAMGQKPITFLRQVSAICLYPELMNDNKFPEDVKQKAARILQACGGHSIGAYSASQGIEVIRQDVAKYIERRDGGIQSDPNNIYLSTGASDSIVTMLKLLVSGQGKSRTGVLIPIPQYPLYSAALAELNAVQVNYYLDEENCWALDINELRRSLTEARKHCDPKVLCIINPGNPTGQVQSRKCIEDVIRFAAEENLFLMADEVYQDNVYAKGCTFHSFKKVLFEMGPKYSETVELASFHSTSKGYMGECGFRGGYMEVINMDPAVKQQLTKLVSVRLCPPVPGQALLDVIVNPPKPGEPSYKQFMAEKQAVLGNLAEKARLTEEILNQSPGIRCNPVQGAMYSFPRIHIPEKAIKLAQAEGQAPDMFFCMKLLEETGICVVPGSGFGQREGTHHFRMTILPPTDKLKSLLERLKDFHQKFTEEYS
What is the function of this protein?
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
What are the official names of this protein?
Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
Protein: THN23_ARATH
Sequence: MEGKTVIFSVLVMGLVISQIQVEAQKTCCPSQSTRKEFEDCISEGNLQILCSAESGCRDTYVGYCPSGFPYGSLTNSGDVVNVYCKLGCVSSLCGALTSLQKLDTSGKVNVAVERCTKACSTICTKGSKTAVETV
What is the function of this protein?
Thionins are small plant proteins which are toxic to animal cells.  They seem to exert their toxic effect at the level of the cell membrane.  Their precise function is not known.
What are the official names of this protein?
Probable thionin-2.3.
What is the protein family that this protein belongs to?
Belongs to the plant thionin (TC 1.C.44) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_POLSJ
Sequence: MTPANAPAPSPATPSATPYGTLPPAATPSARKPLSLPRLREMHAQGEKITMLTAYDATFAAVADAAGVECILVGDSLGMVCQGLTSTVGVTLETMRHHTECVANGLRRSHATAWLIGDLPFGTYHESKEQALRNAVALMQAGAHMVKLEGGGWTADTVRFLVERGIPVCAHLGLTPQTVHALGGYRVQGKTEEAAATLKREAHELQDAGAAMLVLEMVPAALSAALTQALTHCPTIGIGAGNGTAGQVLVLHDMLGMNLGKMPKFVRNFMDGAPSVRGAMEAYVRAVKDGSFPVNATHAW
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y055_TREPA
Sequence: MNQIRLFAQSALVSVMGMGMVFAFLLLLICVVRCVGALVSSFGWDRGPDEGVGAAVPAGGALAAAIAVAVHEKARSTS
What are the official names of this protein?
Uncharacterized protein TP_0055.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACUM_ASPFU
Sequence: MGCRKSSCPRHHTPKAGTFPPRWFPSAEEPGKKGGQPARPTVVISAGTSEHETITIARRRRTPQLKARHLLSAPANASDLSSSKLIFDVCRSPSDLLLRVPTTNSEHQQAELCATALRPTRSKRLMTENGTAQTGTVPVEQPRNGTMENAKLNMAEGDSSRMESGSKNTASPPVKADNNAAGTHSSPKKRRKVNHACVYCRRSHMTCDSERPCTRCIKRNIGHLCHDEPREPSKRARSEHEHSTAEEDGHSNNEFSNAQSMPRNVDVQDAAGQQILPDGTVALPPSSVSAVQHNTIPSSSAQNSLGHNSQQLLGYNEWLGGQSQFQDMHTFHPSYMFNAPEVTNEYNLLGDFLSSSLLDDGGMFSNDNLQGIYSDPTLINSMANLDNTALLQQAQPSQPTQSQPHQNDSVQGPSSTVVNDKARETYYMTAADPSGSDPPEERMNKLLKAKYDAGLLKPFNYVKGYARLNQYMEKNMKQSSRQKILRQLDKFRPKFRERMQSLTDIELILVEMWFERSLMEYDRVFASMAIPACCWRRTGEIFRGNKEMAELIGVPIESLRDGKLAIHEIIVEDQLVSYWEKFGAIAFDNTQKAMLTSCTLKNPNSSNPGNGIPCCFSFTIRRDNHNM
What is the function of this protein?
Transcription factor that governs genes involved in reductive and siderophore-mediated iron acquisition, and carbon metabolism (PubMed:21062375).  Suppresses the expression of sreA and induces hapX to stimulate expression of genes involved in both reductive iron assimilation and siderophore-mediated iron uptake which is essential for the maximal virulence (PubMed:21062375).  Regulates also genes involved in gluconeogenesis (PubMed:21062375).
What are the official names of this protein?
Zinc cluster transcription factor acuM, Iron acquisition regulator acuM.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOSB_BACCN
Sequence: MLIKGINHICFSVSNLETSIAFYEKVLEGELLVKGRKLAYFRICGTWVALNEETDIPRKEIHQSYTHIAFSIEKEDFERLLQRLKENDVHILQGRKRDVRDCKSIYFTDPDGHKFECHTGTLEERLQYYKEAKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_TOLAT
Sequence: MRIALGIEYFGADYYGWQRQREVNSVQQELETALSRVANHPVEIQCAGRTDAGVNATGQVIHFDTTANRQMSAWTLGINAQLPDDIAVRWAHVVDDNFHARFSATARRYRYIIYNEPLRPGILAKGVSHYYHPLNADQMNEAGQLLLGERDFTSFRAAQCQSNTPFRNIMSLSVHRAGSYVILDIQANAFLHHMVRNIMGSLLLVGTGEKPKEWIGEILDAKDRTVSGATAKAEGLYLVDVTYPLHYGLPKPPLGPLWFNA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RIMK_VIBPA
Sequence: MRIAILSRNENLYSTMRLKQAGEERGHQIDVIDTLHCYMDITSNNPMIRYKGEELPQYDAVIPRIGASITFYGTAVVRQFEMMGTFCVNESVAISRSRDKLRSLQLLSRKGIGLPRTGFAHHPDNIQDVIKNVGGAPLVIKLLEGTQGIGVVLAETNKAAESVIEAFMGLKANIMVQEFIEEAKGADIRCFVVGNKVIAAMKRQAKEGEFRSNLHRGGSAQLVRLSKEERATAVNAAKVMGLNLCGVDILQSKNGPVVMEVNSSPGLEGIELATGKDVAGMIFDFIEKNAKPNSNRTRGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: PYC_PICPA
Sequence: MAEEDYLPVYQLRRDSSLLGTMNKILVANRGEIPIRIFRTAHELSMNTVAIYSHEDRLSMHRLKADEAYVIGERGQYSPVQAYLAIDEIIKIAVKHNVNMIHPGYGFCSENSEFARKVEENGILWVGPSDTVIDAVGDKVSARNLAYAANVPTVPGTPGPIEDVAQATAFVEEYGYPVIIKAAFGGGGRGMRVVREGDDIEDAFLRASSEAKTAFGNGTVFIERFLDKPKHIEVQLLADNYGNVIHLFERDCSVQRRHQKVARNCSAKTLPVEVRNAILNDAVKLAKTANYRNAGTAEFLVDSQNRHYFIEINPRIQVEHTITEEITGVDIVAAQIQIAAGASLEQLGLLQEKITTRGFAIQCRITTEDPTKNFQPDTGKIEVYRSSGGNGVRLDGGNGFAGAVISPHYDSMLVKCSTSGSNYEIRRRKMIRALVEFRIRGVKTNIPFLLALLTHPVFMTSECWTTFIDDTPELFKILTSQNRAQKLLAYLGDLAVNGSSIKGQIGLPKLHKEADIPSITDINGDVIDVSIPPPDGWRQFLLEKGPEQFAQQVRAFPGLMIMDTTWRDAHQSLLATRVRTHDLLNIAPATSYALHHAFALECWGGATFDVSMRFLHEDPWQRLRKLRKAVPNIPFSMLLRGGNGVAYYSLPDNAIDHFLKQAKDTGVDVFRVFDALNDIEQLKVGVDAVKKAGGVVEATMCYSGDMLKPGKKYNLEYYINLATEIVEMGTHILAVKDMAGTLKPTAAKQLISALRRKFPSLPIHVHTHDSAGTGVASMVACARAGADVVTVRVNSMSGMTSQPSMSAFIASLDGEIETGIPEANAREIDAYWAEMRLLYSCFEADLKGPDPEVYQHEIPGGQLTNLLFQAQQVGLGEKWVETKKAYEAANRLLGDIVKVTPTSKVVGDLAQFMVSNKLSSEDVERLASELDFPDSVLDFFEGLMGTPYGGFPEPLRTNVISGKRRKLTSRPGLTLEPYNIPAIREDLEARFSKVTENDVASYNMYPKVYEAYKKQQELYGDLSVLPTRNFLSPPKIDEERHVTIVTIETRKTLIIKCMAEGELSQSSGTREVYFELNGEMRKVTVEDKNGAVETITRPKADAHNPNEIGAPMAGVVVEVRVHENGEVKKGDPIAVLSAMKMEMVISSPVAGRIGQIAVKENDSVDASDLIPKSSRLSKLLMFIILIILY
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase, Pyruvic carboxylase, PCB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCYA_RIPO1
Sequence: MLDTSPVSIRSQLNPLICQLAEVILSHWQEYLSLSLYKLPDGLGYVEGKLEGERLVIENRCYQAPQFRKMHLELAKVGKGLDILHCVMFPNPDYSLPMFGCDIVANSRAVSAAIADLSPANAELTLSPTYQKALSQLPSLDFRESRDLPEWGDIFSEYCLFIRPTNAEEETQFINRVADFLKIHCQLAVQSQPVSVEQETLNLAGQKYYCTKQQQNDKTRRVLEKAFGQEWADKYITQVLFDLPY
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.