PharMolix/UniProtQA huggingface dataset:
Protein: ENTP5_HUMAN
Sequence: MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGFEPCYAEVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLLQSLGISH
What is the function of this protein?
Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (PubMed:15698960, PubMed:10400613).  In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases.  UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose.  Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose.  Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (By similarity).
What are the official names of this protein?
Nucleoside diphosphate phosphatase ENTPD5, CD39 antigen-like 4, ER-UDPase, Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Inosine diphosphate phosphatase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted.
Protein: LHB2_RHOSU
Sequence: MTDDMDKVWPTGLTLAEAEEVHKQLIDGTRVFGAIALFAHFLAAIATPWLG
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/850 beta chain, Antenna pigment protein beta chain, LH-3B.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: RMF_IDILO
Sequence: MKRQKRDRFERAHTQGFKAGLHGRSKDNCPYQTQDDFRSHWLGGWRDAMEARNTGLFR
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_HAEIG
Sequence: MAFKFNAEVRTAQGKGASRRLRHNGQIPAIVYGGSEEPVSIILNHDELNNAQAHESFYSEVITLVIGGKEVAVKVQAMQRHPFKPKLVHIDFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: PDXH_IDILO
Sequence: MDLQAMRREYGLGSLHREQLEADPVKQFEKWMQQAIDSNLLSDPTAMTLATVDAEHMPSQRIVLLKGYDHTGFRFYTNKNSHKGQDISENPQVALHFAWLPLERQISIIGSAVPLDDDDNDRYFHSRPKESQVAALASQQSRPVESRDVLESHYQSLLKDYENTEVPRPQSWGGYCVHPKQFEFWQGGQHRLHDRYQYSKDRENWRITRLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: SOTI_DROPS
Sequence: MDPRMYRLIRLPSYGLGNNNNDPNQQRGERQRQPHPDLGWILDAPNEPPRNRNPLLYLVTAPPRPRKKRSFMTTSKPFRIQTNVSDLQYNAWQAIQDAPPEKRCEYYVKYMDEHMNSQNYPNGMGLPHRWGQF
What is the function of this protein?
Post-meiotically transcribed gene that has a role in late spermiogenesis; required for actin cone progression during spermatid individualization.
What are the official names of this protein?
Male-specific protein scotti.
What is the protein family that this protein belongs to?
Belongs to the male-specific scotti family.
Protein: GENL1_ARATH
Sequence: MGVGGNFWDLLRPYAQQQGFDFLRNKRVAVDLSFWIVQHETAVKGFVLKPHLRLTFFRTINLFSKFGAYPVFVVDGTPSPLKSQARISRFFRSSGIDTCNLPVIKDGVSVERNKLFSEWVRECVELLELLGIPVLKANGEAEALCAQLNSQGFVDACITPDSDAFLFGAMCVIKDIKPNSREPFECYHMSHIESGLGLKRKHLIAISLLVGNDYDSGGVLGIGVDKALRIVREFSEDQVLERLQDIGNGLQPAVPGGIKSGDDGEEFRSEMKKRSPHCSRCGHLGSKRTHFKSSCEHCGCDSGCIKKPLGFRCECSFCSKDRDLREQKKTNDWWIKVCDKIALAPEFPNRKIIELYLSDGLMTGDGSSMSWGTPDTGMLVDLMVFKLHWDPSYVRKMLLPMLSTIYLREKARNNTGYALLCDQYEFHSIKCIKTRYGHQSFVIRWRKPKSTSGYSHSHSEPEESIVVLEEEEESVDPLDGLNEPQVQNDNGDCFLLTDECIGLVQSAFPDETEHFLHEKKLRESKKKNVSEEETATPRATTMGVQRSITDFYRSAKKAAAGQSIETGGSSKASAEKKRQATSTSSSNLTKSVRRRLLFG
What is the function of this protein?
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA with a specific cleavage site in the 5' overhang strand exactly one nucleotide 3' of the branch point (PubMed:25037209).  Structure- and sequence-specific nuclease that resolves holliday junctions (HJs) by symmetrically oriented incisions in two opposing strands near the junction point, thus leading to ligatable products; HJs are physical links between homologous DNA molecules that arise as central intermediary structures during homologous recombination and repair in meiotic and somatic cells (PubMed:25037209).  Structure-specific nuclease with 5'-flap endonuclease activity, preferentially cleaving static flaps 5' overhang strand exactly one nucleotide in the 3' direction of the branch point (PubMed:25037209).  Also able to cleave double-stranded flap strand 1 exactly at the branch point (PubMed:25037209).
What are the official names of this protein?
Flap endonuclease GEN-like 1, AtGEN1, XPG-like endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLB_ECOL6
Sequence: MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKSDDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAVARAANVGVIIERGNNLKENN
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.  Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin at appreciable velocity.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, Dihydroneopterin epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: ENO_DICTD
Sequence: MPAILDVHGREVLDSRGNPTVEAEVYLEDGSVGRAIVPSGASTGSREALELRDNDPKRYKGKGVLQAVKNINEIIAQELIGLEALNQYTVDKTMLELDGTENKSRLGANAILAVSLATARAAAASLGVPLYVYLGGVQARELPTPLMNVINGGKHADNPLDFQEYMIVPLASTFKESLRWAVEVFHTLRSILKSKGLNTNVGDEGGFAPYLEKNEDPLAILVEAIQKAGFEPGKDVALALDLAASEFYEDGKYILKAEGKELTSDEMISLLEYLCDKYPIVSIEDGLSEKDWDGWKKLTDKLGKRVQLVGDDIFVTNPQILAEGIEKGIANAILVKVNQIGSLTETLDTIRIAHQAGYRTVISHRSGETEDTFIADLAVAVNSGQIKTGSLSRTDRIAKYNQLLRIEEDLGEAALYRGILNFKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PDZD8_HUMAN
Sequence: MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYLYGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGEALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQTLQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEEEAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVPLPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKDVTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGFNDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPGTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKSGERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPFSSISDDLFGPSESV
What is the function of this protein?
Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544).  PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544).  In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544).  Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987).  May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).
What are the official names of this protein?
PDZ domain-containing protein 8, Sarcoma antigen NY-SAR-84/NY-SAR-104.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes at mitochondria-endoplasmic reticulum contact sites.
Protein: TATA_ACIBY
Sequence: MAGLSIWHVVIFAIVVILLFGTSKLKNIGKDVGGAVRDFKKSVREEDEAASLNSPRTIDAQVKTSESTSVKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SP5G_BORRA
Sequence: MNITNVRIRRVDNKDSSSKLLAYVTVTFDDCLVLHNIRVIRGQKGVFIVMPNRRTKVGEYKDIVHPINQSFREILQSAIFKEYVKENPANFELELV
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: SLB6_MACLB
Sequence: DCPWDWSSHEGHCYKVFKLRKTWEDAEKFCTEQARGGHLISLKSTEEVDFMIKLAYPILKANLVWIGLRDFWRDCHMGWRDHANLLYKAWSDEPNCSVAKTTDNQWFRRKCNISQYFVCQSRVPR
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec B6, C-type lectin B6.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_BDEBA
Sequence: MMSPQEQLERIKFGTADFINDEDMLKKLKRSIETKKPLNIKLGADPTRPDIHLGHTVVINKLKTFQDLGHKVSFLIGDFTAMIGDPSGKNSTRPMLTREEIEENGRSYAKQIFKILDPEKTEIVYNSSWIMKMTPAEFITMTSKYTVAQLLEREDFTKRYRSGTPIGIHEFIYPLTQGYDSVALKTDVELGGTDQKFNLLVGRAMQAAYGMEAQCVLTMPILEGIDGVNKMSKSLDNYISVVDTPKDMFGKTMRISDELMYRWYELLTDVGAAGLNQLRADVAEGRKHPRTVKVELAKFLIKRFHSQAEAQAAEDEFNRIFVEKGLPDEVPDFEVEAETQMGLAALMVKAQLAASNSEAGRLIQGGGVQIDGEKVSDPRLKIDLKSGASFVLKAGKKKFVKIVVK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_PROMS
Sequence: MEGQNKSITFDGREIRLTTGLYAPQASGSVMIECGDTSLLVTATKTAKKEPSDFLPLICDYEEKLFAAGRIPGGFMRREGRPPERATLIARLIDRPMRPLFPTWMGDEIQIVASCLSLDERVPADVLAVTGASIATLVGEIPFYGPMAAVRVGLIGDDFILNPSYREIEKGDLDIVVAGSPDGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKSQEDLLQDLGIKQIKPSEPEEDKTLPSYLEKNCTKPIELVLKKFDLSKEERDLELEKIKTETQSKIDSLKDDNQVKVLTSENEKLLHSDFKKLTKKLMRSQIINDGKRVDGRDLDEVRKISASAGILPKRVHGSALFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETRPMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKEGKEVRILTDIQGIEDFLGDMDFKVAGTDKGITALQMDMKITGLPVSIISDAIKKARPARIHILEKMQGAIDKPQESLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTRIIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVGQNNGMSYPEPTPTPVAPLN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_BACMK
Sequence: MLERTLRVLEYNKVKEQLLEHTASSLGRDKVKNLVPSTDFEEIVELQETTDEAAKVIRLKGHVPLGGISDIRANIKRAKIGSMLSPHELIEIASTMYGSRQMKRFIDDMIDNGVELPILETHVAQIVSLYDLEKKITNCIGDGGEVVDSASDKLRGIRNQIRTAESRIREKLENMTRSSNAQKMLSDAIVTIRNERYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEVERILMMLTEEVAVEADIVLSNVEVVANLDFIFAKALYAKRIKATKPIVNNERYMDLKQARHPLIDPEIIVPNNIMLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVMDESEICVFKNIFADIGDEQSIEQNLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVCNRGARVVATTHYPELKAYGYNREQVINASVEFDVNTLSPTYKLLIGVPGRSNAFEISKRLGLSDRVIDRARNHISTDTNKIENMIAKLEESQKNAERERKEAEEHRKQSEKLHRELQRQIIEFNDERDEKLLKAQKEGEEKVEAAKQEAEGIIQELRQLRKAQLINVKDHELIEAKSRLEGAAPELVKKQKVNVKNTAPKQQLRSGDEVKVLTFGQKGQLLEKVSDTEWSVQIGILKMKVKESNMEYINTPKQTEKKAVASVKGRDYHVSLELDLRGERYEDAMMRVEKYLDDAQLASYPRVSIIHGKGTGALRQGVQDYLKKHRGVKTYRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: CSRP1_CHICK
Sequence: MPNWGGGKKCGVCQKAVYFAEEVQCEGSSFHKSCFLCMVCKKNLDSTTVAVHGDEIYCKSCYGKKYGPKGYGYGMGAGTLSTDKGESLGIKYEEGQSHRPTNPNASRMAQKVGGSDGCPRCGQAVYAAEKVIGAGKSWHKSCFRCAKCGKSLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALIHSQ
What is the function of this protein?
Heat stable protein, that interacts with zyxin/ZYX.  May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
What are the official names of this protein?
Cysteine and glycine-rich protein 1, Cysteine-rich protein 1, CRP, CRP1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associates with the actin cytoskeleton.
Protein: UPP_HAEDU
Sequence: MKVVEVKHPLVKHKLGLMRSADINTKDFRALATEVGSLLTYEAATDLETELVEIDGWCGKVEVERIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFTKLANDVEERLAIIVDPMLATGGSMIATIDLLKKSGCKHIKVLVLVAAPEGINALQAAHPDIELFTASIDSHLNQHGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RNFE_CROS8
Sequence: MNDVKSILVNGLWKNNSALVQLLGMCPLLAVTSTATNALGLGLATTLVLTLTNASISAFRRWMPGEIRIPIYVMIIAAVVSIVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKNGPLLSALDGFAIGLGATGAMFVLGSLREILGNGTLFDGADGLLGSWARVLRIEVFHTDTPFLLAMLPPGAFIGLGMMLAVKYLIDERMKRRAAKPVVVEAAAEKAS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL1_VIBVU
Sequence: MAKLTKRMRVIREKVDVTREYEINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRDIRVAVFAQGANAEAAKEAGADIVGMEDLAEQVKKGEMNFDVVVASPDAMRVVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFSAEQIKENLEALLVALKKAKPSSAKGSYLKKVSISTTMGAGVAVDQGTLNTQA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TVP23_VANPO
Sequence: MEQINNFYSTILKSSHPFLLSIHLGGKAVPLIFYVLGSLFMGFTAQFISVVLLLAFDFYITKNISGRKLVQLRWWYDTTGKQSSSFTFESYKQFSPGPSINPIDSKLFWWSIYLTPIVWIVFGIMCILRLKLFYFLLVSVGICLTGINAYGFRSCDKWEPNANEDSNNSWFQLPTIPGLDNLNALSQVQSFFQSRSG
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: UVRC_STRPM
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SHEB5
Sequence: MTKTERYAQLRSMIPEMRRIKRIHFVGIGGAGMGGIAEVLVNEGYQVSGSDIAQNAVTDRLCLLGAKIQIGHAAENVQQVDVVVVSTAINLENPEILAAKELRIPIVRRAEMLAELMRYRHGVAIAGTHGKTTTTSLIASVYGQAGRDPTFVIGGLLNSAGTNARLGTSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYGGDFEKLKSTFVDFLHNLPFYGVAVVCIDDAVVREIMPRIGRQLVTYGFSDDADVQALNFSQQGHQCRFTVRRKGKADLDLVLNLPGQHNVLNALAAIAVATEDEIDDSAITQALVEFQGIGRRFQHLGKFATPKGEVMLVDDYGHHPSEVAATIKAARAGWPDKRLVMAYQPHRYTRTRDLYEDFVEVLSQVDCLLLLDVYSAGEAPITGADGRALCRSIRLRGQLDPIFIASPDQLAEVLPDVLQEGDLLLTQGAGNIGALSRLLATTELGFAVAELPAQAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_CLOK5
Sequence: MKVLFAASESHPFVKTGGLADVIGTLPRYLKKIGVDVRVVIPKYSAIKSHLASEFNFIKYFYVPVGWRNKYCGIFQCEYMGVIYYLIDNEYYFFRDELYGYYDDGERFAFFDRAVLDMLWQINYKPDIIHCNDWHTGMIPVLYKIQYKQSSFYRGVKFVFSIHNLLFQGNFDKNILGELFNLDGSLYENGSVELNGAVSFMKSGINYSDKISTVSRSYAFEIQSPEYGENLDGLLRSRSSDLWGIVNGIDYDIYNPEKDNMIFRNYNKNNLRNKMINKLKIQNDLNLDINENVPVLAIISRFTPQKGMDIIKTIGERLVSKHVQLIVLGTGYNEYEEYFRYLSSKYPRNVSTNIYFDDVLAHKIYAASDMFLMPSLFEPCGLGQLIALRYGTIPIVRETGGLKDTIIPYNKYTGEGNGFSFANFDGDDLLRIINDAVDYFEEKDIWNNIVTHAMESNNSWDNSAKPYKSLYESLL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SKP1_YEAST
Sequence: MVTSNVVLVSGEGERFTVDKKIAERSLLLKNYLNDMHDSNLQNNSDSESDSDSETNHKSKDNNNGDDDDEDDDEIVMPVPNVRSSVLQKVIEWAEHHRDSNFPDEDDDDSRKSAPVDSWDREFLKVDQEMLYEIILAANYLNIKPLLDAGCKVVAEMIRGRSPEEIRRTFNIVNDFTPEEEAAIRRENEWAEDR
What is the function of this protein?
Essential component of the E3 ubiquitin ligase complex SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins like phosphorylated SIC1.  Participates in the attachment of chromosomes to the spindle.  Acts as a regulatory component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules.  CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA.  It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromeres and in several promoters.  The association of CBF3C with CBF3D and SGT1 is required for CBF3C activation and CBF3 assembly.  SKP1/CBF3D could retrieve cyclins or cyclin-CDK-like proteins into the kinetochore thus providing cell cycle-regulated kinetochore activity.  Involved in the regulation of methionine biosynthesis genes.  Facilitates association of CDC53 with CDC4 and of ROY1 with YPT52.
What are the official names of this protein?
Suppressor of kinetochore protein 1, Centromere DNA-binding protein complex CBF3 subunit D, E3 ubiquitin ligase complex SCF subunit SKP1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore.