PharMolix/UniProtQA huggingface dataset:
Protein: Y1535_STRPN
Sequence: MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRARLPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL
What are the official names of this protein?
UPF0213 protein SP_1535.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: GLMM_RHOPA
Sequence: MSRRYFGTDGIRGRANGLITPELALKVGQAAGLAFQRGEHRHRVVIGKDTRLSGYMIENALVAGFTSVGMDVLLVGPMPTPAVAMLTKSMRADLGVMISASHNLFEDNGIKLFGPLGYKLSDDVEKQIELMLDESLDKKLAQSASLGRARRIDGVHDRYIEFAKRTLPRELSLEGLRVVIDCANGAAYKVVPEALWELGADVISIGVEPDGFNINKECGSTAPQALCAKVREMRADIGIALDGDADRVILVDERGHVVDGDQLLAVIGQSWKEDGRLAKPGVVATVMSNLGLERFLAGEGIALLRTPVGDRYVLEQMLKDGYNVGGESSGHIILSDFNTTGDGFVAALQVLAMVQKLGRPVSEVCHRFDPLPQILKNVRYRSGRPLDDSGVISAIQDGEKRLNGHGRLLIRPSGTEPVIRVMGEGDDHDVVEEVVDSIVDALGNAAAAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GMHA_NEIM0
Sequence: MTTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFNHVFSKQVRALGRAGDVLVGISTSGNSANVIEAVKAAHERDMHVIALTGRDGGKIAAMLKDTDVLLNVPYPRTARIQENHILLIHAMCDCIDSVLLEGM
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBARP_HUMAN
Sequence: MQPTATMATAATTTTTTTATVALTTSWDNATGRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWDVHQRLNRAMEEAEKTTTTYLDNGTHPAQDPDFRGEDPECQDAETERFLSTSSTGRRVSFNEAALFEQSRKTQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIVTIHECDSGEASSATTPHPATSPKATLAIFQPPGKALTGRSVGPSSALPGDPYNSAAGATDFAEISPSASSDSGEGTSLDAGTRSTKAGGPGAAAGPGEAGPGSGAGTVLQFLTRLRRHASLDGASPYFKVKKWKLEPSQRAASLDTRGSPKRHHFQRQRAASESTEQEEGDAPQEDFIQYIARAGDAVAFPHPRPFLASPPPALGRLEAAEAAGGASPDSPPERGAGSAGPEQQQPPLEPDAERDAGPEQAQTSYRDLWSLRASLELHAAASDHSSSGNDRDSVRSGDSSGSGSGGAAPAFPPPSPPAPRPKDGEARRLLQMDSGYASIEGRGAGDDTEPPAAPARPRSPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDTPAAARHRARAHPHARKQWQRGRQHSDPGARAAPALAGTPAPPAGAARPARAPLRRGDSVDGPPDGRTLGGAGDDPAIPVIEEEPGGGGCPGSGLCVLPSGSVLDKLAAGLDERLFPPRLAEPVVATPALVAAAPTSPDHSPA
What is the function of this protein?
Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits.  Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.
What are the official names of this protein?
Voltage-dependent calcium channel beta subunit-associated regulatory protein.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type III membrane protein. Cell membrane; Single-pass type III membrane protein. Cell projection, growth cone.
Protein: BORE2_XENLA
Sequence: MPPKRNRNRLGTRGEGSGDSGVGMFERNDAVQEHKKEKIRLFMQDFVQQGKDRLAELKKDLESLSTTADKALEVELLKMPLAIRHMKVQDYLSLMGGDKSAVAAAAVKLDCSVDELSEPKLVRKNSKKVKVTTNVEYQDDVRTKVMTTSTKNRTVQKVPKSKSMLSLTGKNGKKTTALTRSVSATPLDKASKKLLVTNSSSKPAQRSSRTAMTPLTRSARSDTMFTFGDGAFLDEGVPFVKIPLADGKTVFSAGDDLDSLNVELLRGDTVQHIHNLVGQLTSLCAKASIQHHGNTL
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.  Contributes to CPC function by facilitating loading of the CPC onto chromosomes.
What are the official names of this protein?
Borealin-2, Cell division cycle-associated protein 8.2, Cell division cycle-associated protein 9, Dasra-A, DasraA, xDasraA.
What is the protein family that this protein belongs to?
Belongs to the borealin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis.
Protein: SYQ_PSEMY
Sequence: MSKPTVEKAANFLRPIVQADLDSGKHAKIVTRFPPEPNGYLHIGHAKSICLNFGLAEEFGGQCNLRFDDTNPAKEDQEYIDAIKADVEWLGFKWAGEERYASDYFDQLHAWAVELIKAGKAFVCDLNAEEMRTYRGSLTEPGKNSPFRDRSVEENLDLFARMKAGEFPDGARSLRAKIDMASPNINLRDPILYRIRHAHHHQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWFLENLPVPAQPRQYEFARLNLNYTITSKRKLKQLVDEGHVQGWDDPRMSTLSGYRRRGYTPASIRAFCDMIGVNRAGGVVDIGMLEFAIREDLDANAARAMCVLKPLKVVITNYPEGKVENLELPRHPKQDMGVRVLPFSREIYIDASDFEETPPDGFKRLIPGGEVRLRGSYVIRADEAIKDAAGNIVELRCSYDENTLGKNPEGRKVKGVIHWVPAAESVECEVRLYDRLFRSANPEKSEEGGSFLDNINPDSLVVLTGCRAEPSLAQAAPEERFQFEREGYFVADLKDSQPGKPVFNRTVTLRDSWGQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_VIBC3
Sequence: MPELPEVEVSRLGISPHLVGGTIQSLVLRTPKLRWPIPQELKQLEGQTILAIHRRAKYLIIETAVGSAIVHLGMSGSLRILDGDFPAAKHDHVDLVMTSGKRLRYNDPRRFGAWLWCAPDESHEVLGRLGPEPLTEAFNAEYMMDKARNKRIAVKAFIMDNAAVVGVGNIYANESLFTSRLHPLRPAHSLSLEEWQTLVANIKQVLQVAIKQGGTTLKDFTQSDGKPGYFAQELQVYGKAKQPCPHCGEPLCEQKIAQRNTFFCPQCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: STP22_YEAST
Sequence: MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSLRPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLENFDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHEPPQDQAPSLPPKPNTQLQQEQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISPTNHHEMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKNHLRAVEQAIEQTMHSLNAQIDVLTANRAKVQQFSSTSHVDDEDVNSIAVAKTDGLNQLYNLVAQDYALTDTIECLSRMLHRGTIPLDTFVKQGRELARQQFLVRWHIQRITSPLS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).  Mediates the association to the ESCRT-0 complex.  Required for vacuolar targeting of temperature-sensitive plasma membrane proteins STE2 and CAN1.
What are the official names of this protein?
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ESCRT-I complex subunit VPS23, Vacuolar protein sorting-associated protein 23.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Late endosome membrane; Peripheral membrane protein.
Protein: LSPA_BURM7
Sequence: MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHALTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALGIGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IFNW1_BOVIN
Sequence: MAFVLSLLMALVLVSYGPGGSLGCDLSPNHVLVGRQNLRLLGQMRRLSPRFCLQDRKDFAFPQEMVEVSQFQEAQAISVLHEMLQQSFNLFHKERSSAAWDTTLLEQLLTGLHQQLDDLDACLGLLTGEEDSALGRTGPTLAMKRYFQGIHVYLQEKGYSDCAWEIVRLEIMRSLSSSTSLQERLRMMDGDLKSP
What are the official names of this protein?
Interferon omega-1, IFN-omega-c1, Interferon alpha-II-1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRM72_DROME
Sequence: MGRTSKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEGLTRAVDLCAAPGSWSQVLAKRLYEPLPPEEREKVKIIAVDLQGMAPIEGVKQLRADISKESTAEAIIEFFGGEKAQIVVSDGAPDSTGMHDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTSRLYTQLKRFFKNVCVFKPSASRNSSIEAFVVAREFCLPDGYKPCNLTTEWHDQPESWVGRKKESPPVVQVPFVAYKGELDSDRTYDLGENYVYKEPVQQPLTAAYQDILQKTSQVNIKYEGIRVIHDEEMLKKWLENDENKSEKLGACVT
What is the function of this protein?
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
What are the official names of this protein?
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 2, 2'-O-ribose RNA methyltransferase TRM7 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPI10_ANOGA
Sequence: MLNALGVIVSGRLVQTDFQQISDSHFLITIPDADNVNHVVVFLTGTTPFPDGMAGGVYFSWPDPNAPPNWQLLGYISNTKPSAIFKISQLKKLDEIAGQSTMMNNVFGSNLPISHIAQIGVSIEPESSLVQQTPSTTTSSTYYQFGQKIVENFFNFVSSFSITQSQMTPAPNETFVPLSTVQTWYTNFERRLQQNPNFWKN
What are the official names of this protein?
Protein OPI10 homolog.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
Protein: SFI1_PAPAN
Sequence: MSSRWLNFHEKMIKQRMEKKVDSRYFRDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKEEWWVFHHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYTRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRSILRVWWSMWRQQLGQVRVSRALHASAVKHRALSLQLQAWSQWREQLLYVQKEKQKVVSAVKHHRHWQKQRFLKAWLEYLQVRRVKRQQNEMAERFHHVSVLQIHFCDWQQAWEQRQSLYAYHAQVEKLARKMALRRTFTHWKHYMLLCAEEAAQCEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHRQHGVTLLHRFWNLWQSQIEEKKEREQLPLLHAAWDHYRIALLCKCIKLWLQYTQKRRYKQRLQARADGHFQQRTLPAAFHTWKRLWRWRQQDNVLNARATRFHRETLEKQVFSIWRQKTFQHQENRLAERMAILHAERQLLHRSWFTWHQQAAARHQEQEWQTAACAHHRHGRLKKAFCLWRESAQGLRAERTGRVRAAEFHVAQLLRRAWSQWRECLAVRGAERRKLMRADRHHQQRVRHRALQAWVTYQGRVRSILQEVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASAHYRRTICSKVLVQWREAVSVQIYYRQQEDSAFWEARKVLDRGCLRTWFQRWRDCSRRSAQQRLQLERAVQHHRRQLLLEGLARWKMHHLECVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQQATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQRALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVHRCATLWKQKVLGRGGKPQPLAAVAPSRKVTFEDPLLNCIAAGAGDATVGTKRPQAPLLQGALGCLAAEEPHARELNTAHSARKQPRRPHFLLEPARSQRPQKPKEHGLGMAQPAGPSLTRPFLAEAPTAQVPHSPGPGALSSAPGPKQIPTASTGPELLLLPPSSFMPCGAAAPARASAQPATPRDKPQVPPSLASVPDPHLLLPGDFSATRAGPGLSTTGSLDLEAELEGIQQQLLHYQTTKQNLWSCQRQASSLRRWLELSREEPGPEDQEVEQQVQKELQEVELQIQQLAEELQAQRQPIGTCIARIQALRQALR
What is the function of this protein?
Plays a role in the dynamic structure of centrosome-associated contractile fibers via its interaction with CETN2.
What are the official names of this protein?
Protein SFI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SFI1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized close to the centriole.
Protein: NOX4_HUMAN
Sequence: MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGLTGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTNLDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLYRYIRSNKPVTIISVMSHPSDVMEIRMVKENFKARPGQYITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRFEYNKESFS
What is the function of this protein?
Involved in redox signaling in vascular cells.  Constitutively and NADPH-dependently generates reactive oxygen species (ROS).  Modulates the nuclear activation of ERK1/2 and the ELK1 transcription factor, and is capable of inducing nuclear DNA damage.  Displays an increased activity relative to isoform 1.
What are the official names of this protein?
NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Note=May localize to plasma membrane and focal adhesions. According to PubMed:15927447, may also localize to the nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Nucleus. Nucleus, nucleolus.
Protein: RPOE_BACC2
Sequence: MNFKQYSPEELKECSMIEVVHSVLGDKRQATTFNELVQEIAQVLGLSQEQVNAKLAQFYTDLNIDGRFINLGENRWGLRSWYPYEQIDEEILPQPKPKKKRKVEEDGFDDYIEEDEDDFDDADGNADEEDDVEDLDKVLEEEDGDDDDLDDLEEDEEDDFAEEELEYDETEEEEEEL
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: SYC_NOCSJ
Sequence: MTFRLYDTATREVRDFVPLEEGKAGLYVCGLTVQSEPHVGHVRSGVNFDVLQRWLRHLGYDVTFIRNVTDIDDKILVKSAEQGLAWYQLAYRMKRQLDRAYDDLNVAPPTYEPAATGHVPEMIVLIQELIAKGHAYAAEDGSGDVYFDVRSWPQYGELTRQGIDDMEAAEDADPRGKRDPRDFALWKGWKKDSEPETAAWPSPWGPGRPGWHIECSAMAGKYLGPAFDIHGGGVDLRFPHHENEQAQSRAAGRPFATYWMHNAWITTAGEKMSKSLGNSLTIPAVLQKYRGIELRYYLVAAHYRSHVEFSFEALDEAATGFRRIENFLDRAADVLGGIGGGIACADFLNAMNDDLGTPAAVAAIHEVVREGNKLLAAGDSPALRGNAASVVAMLDVLGLDPADPAWSSPGGGRTAERLETVVEGLVSDLLTQREKARADRDFVSADAIRDRLHAVGVQLEDTPDGPKWSLS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_LEUMM
Sequence: MNKIVVLTGPTASGKSSLSIQMAQRLNGEIVSADSMQIYRNLDVGTAKVTKEEQNIVPHHLIDIVDLTANYSVGDFIIAADKVIADIISRGKLPIIVGGTGLYVKALLGFQELEYAASDTEEVHKLNAYELDKLVVELKSLDINRAQKVDLKNKQRVIRAIQIAKYGKKDAKLTQRPKYDALVIGLDWPRELLYERINHRVTQMVQDGVLKEAQTILDAGGEKLQSGKAIGYKEFFPYLRDQVTLDKAINQLQQDSRRYAKRQLTYLRHQIPGLVWLKGQTAELRLTEMIEGWLSLK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ACKA_FERNB
Sequence: MRVLVVNCGSSSIKYQFLDMDTEQVLCKGLAERIGIPGSRIVHKKDDQKVVVEKPMKDHEDALKYVLELVVDEKVGGVKDLKEIDAVGHRVVHGGEKFSGSVLIDEEVMRALEEYSYLAPLHNPPNIMGIRAMMKLLPGVPNVAVFDTAFHSKMPAKAYLYAIPYEYYKKYKIRRYGFHGTSHRYVSKRTAEILGLDYHKSKIITVHLGNGASIAAVMNGHSIDTSMGFTPLEGLVMGTRSGDIDPSIVTFLMEKEGLTAEEVYTILNKKSGVLGLTDGFSSDMRDIEGKALEGDPVCRLALDIYEYRIAKYIGAYIAAMNGVDAIAFTAGVGENSPITRKEICENYLSYLGIKIDDEKNNVKGEERIITTPDSKVKVLLVPTNEELMIARDTKEIIEKGLKQLEY
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_BRUMB
Sequence: MTTELHDDASGRLIVGLDVPTIAEAEKVVEELGNAVSFYKIGYQLVFAGGLDFAKSLVAARKKVFLDMKLLDIDNTIAKGVENVAKMGVSMLTLHAYPKAMRAAVEAARGSDLCLLGVTVLTSMDNADLREAGYFDNAETLVLKRARQAHEAGMGGIVASAVEAQAIRQAVGPDMAIVTPGIRPAGSEKGDQKRVMTPADALRAGASHLIVARPIVGAPDRKAAALAILKEMRSIGRS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: MSBA_SHEFN
Sequence: MSASPKNEMWVVFKRLMAYVVPMKAMFIMAVLGLITYGAVDAAFIAFIKPFIDEGFSQTPAIVAGVDLPTHGGFNANKDIMLMAPIAVILMFSLRGVANFVSTYCVSYMSAQLIMDMRQQVFEHYLRLPVSYIDRENSGNLISRVTFDTEQIARASGSALISIVRDSMTAIGMLGIMFYYSWKLSLCILVIGPIMGVVISVVSKRFRKVSKQIQSAMGGVTATTEQMIKGHKNVLVFGGQKTEVERFFQVNDRNRYQNMKLAVAQSISQPLIMVIGSFALAFVLYAATWDSMKTDLTAGTFAAILGAMLAMLQPIKNLTRVNAEFQRGIAACTTVFELLDTAPEPDNGVFSIDRVEGKLAFDNVTFAYPGQEKSALNGINFEVKPGKTVALVGRSGSGKSTIASLITRFYGDLSTGDIRLDDTSIYDYQLKSLRNQVALVSQQVTLFNDTIANNIAYAYPGEVTREQIVHAAELAYAMEFIDTLPEGLDTQVGENGVLLSGGQRQRIAIARAMLRDAPVLILDEATSALDTESEKAIQKGLDNLRHNRTSIVIAHRLSTIESADEILVIDQGKIVERGNHSELIAQAGIYANLYQMQFSQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADD_SHESW
Sequence: MIDTSIPLVDLHRHLDGNVRVNTIWELGHQHGIALPADSLETLAPFVQIQGKETSLVAFLKKLDWMVAVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHKLPIEGVVEAVVDGVKAGLKDYNVKINLIGIMSRSFGQAACTQELEGLLAHKQHLVAMDLAGDELGFPGELFNDHFKRVRDAGLAITAHAGEAAGSQSMWQAIQELGATRIGHGVNAIHDPRLMEYLAKHRIGIESCPTSNLHTSTVVSYAEHPFRTFMDAGVLISLNTDDPGVSAIDIKHEYRIAKSELKLTDAELAQVQRNGVEMAFLSDSERKALYAAKV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: CAPL_STAAU
Sequence: MNRNIAVVGLGYVGLPVAVTFGNKHKVIGFDINESRIKELKNNYDRTNEVTENKLKNTNIEYTSNAEDLKKADFIIIAVPTPIDKHNKPDLLPLLKASETVGKVITPDTIVVYESTVYPGATEEECVPVLEKYSGLVCGKDFFVGYSPERINPGDKVHTFETITKVVSGQTLEVLEIVADVYSSVVTAGVHKASSIKVAEAAKVIENTQRDVNIALMNELAIIFDKLDIDTNEVLKASGTKWNFLNFKPGLVGGHCIGVDPYYLTHKAQEVGHHPEVILAGRRINDNMAKYIASNVIKELLKQGLEVQGATVNVLGLTFKENCPDLRNTKVIHIIEELKEYGLNVTVNDVEADKNEAKKFFGLDLIDTKELKMVDVVLFAVPHKDYMENKKDYINLVKDCGIVFDIKGIINSDELNVSQRLWRL
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Protein CapL.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: MURA2_STAHJ
Sequence: MDKIVIKGGNRLTGEVKVEGAKNAVLPVLTASLLASEGQSKLVNVPDLSDVVTINNVLSTLNANVEYNKEEGAVLVDASTTLKEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGARPIEQHIKGFEALGAEIHLENGNIYASTKDGLKGTDIHLDFPSVGATQNIIMAASLAKGKTVIENVAKEPEIVDLANYINEMGGKVTGAGTDTITIHGVEKLRGVEHSIIPDRIEAGTLIIAAAITRGDVFVRDAVKEHMTSLIYKLEEMGVNLDFQEDGVRVTAEDELKPVDVKTLPHPGFPTDMQSQMIALLLTAEGHKVITETVFENRFMHVAEFRRMNANITVEGRSAKIQGKSQLQGAQVKATDLRAAAALILAGLVAEGTTQVTELKHLDRGYVNFHEKLKSLGANIERVNY
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP2_CLOBH
Sequence: MDLISVILISIGLSMDAFAVSITNGAMISKVTASEGIRIGLFFGGFQALMPLIGWSIGIKFESYIAALDHWIALILLSIIGGKMIYDSVKENQDHKDEIACDYAAGEKKCLNNKTLILLAIATSIDALAVGVSFAFLKVSIINTIIIIGSITFVICFIGVMIGKKCGKLLKKRAEILGGVVLILIGVKIFIQHTNILSYIF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP 2.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSE1_NEUCR
Sequence: MFRAAAAGPYDEAINKATDENLTSEDWGAIMEVCDRVATDANGAKEAVNSMIKRLAHRNANVQLYTLEVANALSQNCGKNMHRELSSRAFTDALLKLANDRNTHTQVKAKILERMKEWSDMFKSDSDLGIMYDAYYRLKQSNPTLQPPSAPQKNVLTDADRQKEEEELQMALQLSLQEEERKKRPAGASGATASSSSGGAAAGPSNAGGAVASGEGTNSTAGQAEATPQPVPSSTTAATVSRVRALYDFVPSEPGELEFKKGDVIAVLKSVYKDWWSGSLKGKTGIFPLNYVEKLADPTPEELQREAQMEAEVFAEIKNVEKLLTLLSAGNTGPREEDNEEISKLYHQTLAIRPKLIKLIEKYSQKKDDFTQLNEKFIKARRDYEALLESSMSHPPGPTYHQYAMRPPMTNSYGSGGYGAPPPQQQQEPPRFYNPAPAQDAPQYPATSPSPNPNHFIRPAGTPAPYYMGGAEGPGQLQHQQQPPYPQQQPQPAYGAPSRPQDQQRNPSGPSPMAPAPLNTTSSPPPGNQYTPYQAPGASGANNRTNSYSSTNGGAPQELSTSAYDSPIAQHSTNPLSNPSYNAPSAPSYSQGRPGAPTDDPYGPTSPGAGSSNNVGSAPPPPSGPAPSGPAPSAPSAPSAPSAPGAPNSYTQGAYHSQNPYAAAAAAAAAAASRTHVPGVYDGAGSEVSSTAPQPPAALQPGGGAQPQYKAYVPPGAPSAPGSGQEGPSAPGQNDGLADYYRSAY
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein hse1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURD_ALCBS
Sequence: MAKDGFDLVIGLGVTGRSVIRYLTDQGMPVRAIDTRAEPVGLDALCADFPDLKVHTGGFKKGWMGKARRLIVSPGVAVSTPAIAEQVVDGKEVIGDIELFARAASEPLVAITGSNAKSTVTTLLGQVADACGMNPGIGGNLGVPALELLDDQARLYVLELSSFQLETTYSLSAEVATVLNVSQDHLDRYASFADYLAAKQRVYDGCQVAVWNRDDLATRPPATVARQISFGAHPEADYRLDSENGQLLCRGEPLLSLSELALTGHHNAMNILSVLAISDALSLNRDKALATVKTFTGLPHRCQLVAESGGVRWFNDSKATNVGATLAALTGIGESIEGKVILVAGGLGKGQDFSPLAEPARQYLRAALLMGEDRTTVAQGMSAAPCELVADMAVAVRRAHALAQPGDAVLLSPACASFDQYSGFAARGDDFTTRAQELCHD
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.