PharMolix/UniProtQA huggingface dataset:
Protein: SNR40_DICDI
Sequence: MENKRKQKDEIVLVNGSNDTTPNKKQKNELQVVSSGGGREIILGTERTSKLEHPIMQLIGHKGEIYSCKFNSYGTALASGGSDKEIFLWNVYGECINYSVLKGHKGTILELHWSTDSNEIYTACTDKSIGVWDSNKGELIKRIREHSGVVNSCCPARRGPPLVASGSDDRSARIFDTRSKGSTHLFQHKYPVTSVCFSDASDQLITGGIDNVIRVWDIRNQEDPLYTLASHQDTITSTSVSKDGAYLLSNSMDNSCKIWDIRPYAPPNRNIKTFNGAQNNFEKNLIKSSWSIDGRRIGCGSSDRQVYIWDTNTKQLQYCLPGHSGTVNEVTFHPNEPIIASCSSDKTIYLGEIKP
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome.
What are the official names of this protein?
U5 small nuclear ribonucleoprotein 40 kDa protein, U5 snRNP 40 kDa protein, WD repeat-containing protein 57 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_BLOFL
Sequence: MYNIIFLGPPGSGKGTQAHLISTKYGISNISAGEILKHALSVTKFHFNFNTDNMLNQINSGNLVDDELIIPLIIKRIRQDDCKKGFILDGFPRTIGQAIAIEQNKIAIDFVIEFNISDSAIINRIVGRQVHIKSGRTYHIKFNPPKLDGIDDITGEKLVIRADDNAQVILQRLNQYRKYTIFLSDYYQKQSQQGNMRYFIINGNQEITKIYKELINIFNFHIFKMN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYI_DROME
Sequence: MALKFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYPEGETSDVVSAVKETGVVVSLVNLAFDKSDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNCGKIHLTAGLFKGGQESDYTKTYTANLKIAADSLRASKMIGVIEPINKYAVPGYYMNSYSKAAGILADVAADNIQLLADLYHLQHLHGNVSKTLEEYKALIGHFQIAQVPHRHEPDVSGELDYGFVFKALQEFGYDGWIGCEYKPKTTTVEGLGWVSKLGYTL
What is the function of this protein?
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
What are the official names of this protein?
Putative hydroxypyruvate isomerase, GIP-like protein, Transient receptor potential locus C protein.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: CISY_RICCA
Sequence: DSEFVELKIRGKIFKLPILKASIGEDVIDISRVSSEADCFTYDPGFMSTASCRSTITYIDGDKGILRYRGYDIKDLADKSDFLEVAYLLIYGELPSSEQYNNFTKKVAVHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTMAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCMKYEVNPVIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSENIPKYIAKAKDKDDPFRLMGFGHRVYKNYDPRAAVLKETCNEVLKELGQLENNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: POSTN_HUMAN
Sequence: MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDASKLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLKNGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDFIEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEALMKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHLIDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSMDQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQGRNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDAFKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVNDTLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGSTFKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETITEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
What is the function of this protein?
Induces cell attachment and spreading and plays a role in cell adhesion (PubMed:12235007).  Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX (By similarity).
What are the official names of this protein?
Periostin, PN, Osteoblast-specific factor 2, OSF-2.
What are the subcellular locations of this protein?
Golgi apparatus. Secreted. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi.
Protein: ZDH14_DANRE
Sequence: MHLGVEEPIRECQYNQICTHNSSPMDTPHIKKKKNKRKWQVFPGRNRFYCNGRIMMAKQTGVFYLTMVLILVTSGLFFAFDCPFLASNLTPAIPAIGGVLFVFVMGMLLRASFSDPGVLPRATPEEAADIERQIDANNGPSGPGYRPPPRTREVLINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGRRNYRFFYLFILSLSFLTIFIFAFVITHVILNALRKALALSTAADFEAVQKDPTGLAFLVLSKTALLDILEVVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSSKRGKGNYNPYSYGNFITNCCSALCGPLPPSLIDRRGFIQPDTPQPATQTNGTSACPPNQVQSHMCAQDQCIQSTKFVLQAATNPLLHSQPVILGGGPPLQAKTSLGGPCSTMGPPQPSLPSSIPGLSCGGELMALRDSEIHCHHHLHHQHFISPEETPSPPAPLPCATHLGHHVHPAQLFDPVSQDSLHEDSVRGLVKLSSV
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.
What are the official names of this protein?
Palmitoyltransferase ZDHHC14, DHHC domain-containing cysteine-rich protein 14, DHHC-14, Zinc finger DHHC domain-containing protein 14.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PRTD_DICCH
Sequence: MNASSERDRSLFGVLRQFRRSFWSVGIFSAVINVLMLAPSVYMLQVYDRVLASGNGITLLMLTLLMAGLCAFMGALEWVRSLLVVRLGTRIDLALNQDVFNAAFARNLEAGDGRAGLALTDLTLLRQFITGNALFAFFDVPWFPLFLLVLFLLHPWLGMLALGGTVVPGGVGLAEPASDQSTAGGSNQQSQQATHLADAQLRNADVIEAMGMLGNLRRRWLARHYRFISLQNLASERAAAVGGASKYSRIALQSLMLGLGALLAIDGKITPGMMIAGSILVGRVLSPIDQLIGVWKQWSSARIAWQRLTRLIAAYPPRPAAMALPAPEGHLSVEQVSLRTAQGNTRLQNIHFSLQAGETLVILGASGSGKSSLARLLVGAQSPTQGKVRLDGADLNQVDKNTFGPTIGYLPQDVQLFKGSLAENIARFGDADPEKVVAAAKLAGVHELILSLPNGYDTELGDGGGGLSGGQRQRIGLARAMYGDPCLLILDEPNASLDSEGDQALMQAIVALQKRGATVVLITHRPALTTLAQKILILHEGQQQRMGLARDVLTELQQRSAANQARMNPTAAMPQ
What is the function of this protein?
Involved in the secretion of proteases A, B, C and G.
What are the official names of this protein?
Proteases secretion ATP-binding protein PrtD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TGAL8_ORYSJ
Sequence: MAYPSTSGMIQASSSLHGSITRRNPEGYDMPSDLDQALLLYFDGQEQDKPSTQEEPHKPLNFVKETLNIFPSQPMDGEPTPTPKASMSAPPIAGFSRRSPAPAAADGRPLTLGKTSKAAFKKEGGSGSGGAMAASASSELKGPKTPDPKTLRRLAQNREAARKSRLRKKAYIQQLETGRIRLAHLEQEIQFTRAQGAFCGAGILSPDAALFNLEYERWQEAHHQVISRLRAAVEEHRPDGELQPHVDEAMSHYGVLMAHKARLVGADPLHLLSGLWKGAVEQCFLWIGGFRPSELIKVVVRHVEPLTEQQLAAVYSAQQAARQEEDALDGGLQALLRSLSDVVSSSDAPSSSQQTPPVMYHPSAAAAMAAASFMGQYGSYSNLQLAMDKLANLAIFLRQADEERMRTLHALRRMLTVRQAARCFVAVDDYFGRLRALALFWTTTRPHPAAG
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL8, bZIP transcription factor 49, OsbZIP49.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XB35_ORYSJ
Sequence: MGLLGMVGDSFGCSATGERLVSAARDGDIQEAMALLELNPRLARYSTFGIRNSPLHYSAAKGHHEIVSLLIESGVDINLRNCRGQTALMQACLYGHWKVVQILVLFKANIHKKDCFSGATAIHFAALKGHTRCLRLLVADYVPSLPEFWSVMHAKCTDETNKEAFDAVALRRLINNKSDGGVTPLHLAALHGHAECVQLLLDLGASVSEVTINDGSTIDLIGSGSTPLHYAACGGSAVCCQLLVAAGANMRAQNTNGLTPLMVARSWHKSSVEGILTKRSEVPVRILPSSYLSLPLMSIVKIARECGWRKTSVSSVCHDPCAICLDTECTVSAEGCGHEFCTKCALYLCATASSSTSIRGVPGSIPCPLCRHTIVSFVRLTSTTPIKELPWTNKSLALCAAGASTGSKYAGPAAITSSKYAGSLHRRSEMRSLRSSSVDLGCSSFRTASSGKLSSIKLNCTGADETMPCLVNCFRPDVQRSSSYRERIRRYSQFS
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase XBOS35, Ankyrin repeat domain and RING finger-containing protein XBOS35, RING-type E3 ubiquitin transferase XBOS35, XB3 protein homolog 5.
Protein: RUVA_CLAMS
Sequence: MISSLRGTVLSVSGQTLLLEVHGVGYGVSVTPRHALELRHGSEATVLTSLVVREDSLTLFGFPGPDELRAFELLCGVTGVGPKSALAVLEHLDPEAMAQAVAAEDDAAFRRVSGIGPKTAKLIVLQLAGKLFVTQPRTRSASSAASTVTADVVTALIGLGWSERVARTAVDDAAAAAAEQGLPADMPRLLRVALGMLGPQQPAGAPAAAQAADR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: YQGF_RALPJ
Sequence: MPEPARPATASVPVEGTLLAFDYGEKRIGVALGNTVSRSARALETIPNRSVDFRFAQISRLVGEWQPVGFVVGMPVHPDGEEQPMIKLAKRFGNQLLGRYGLPVTWVDERYSSIAAQDAGASDDVLDAEAARIILQQFFDEHA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM39_YEAS1
Sequence: MWGLCKNHFPSNKIQVQERNKALKPKKSGSEHKTKQLFPVFNCKKKEKGVMIRFAILRNANTSLLSARSICLFTQAPTYCHVRLNTLNKSITTKRNSLTESKRHVHDGKHFFTTPHQQQQTKLGEIEEGHSPNIKGEDLRSIGQAITHQRNKRRKQIWSAIFGGIFGVILGYSLIYRVIYLKEQSFLPLFPSSKIRKLSTRDLKKVDVNQVQKLSKLRVLEILSGHDMIKEQYGVPLLDKDGNSPTLNEFSMWCEDQDPCVTGIVMEPDDKRDSSHTWYRIPFVCKWRITHRPISIRGTIDDLLNRIGLETSDLFEIISPERVYGSFKYEYPLQGDSHALHLWFHGEIELDDDSLIVYNGKYHVDVKLQEIDLFRREKNGQLIQYVLYKNEAGDK
What are the official names of this protein?
Altered inheritance of mitochondria protein 39, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM39 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SYE_CHLT3
Sequence: MSEQTIRTRFAPSPTGYLHVGGLRTALYNFLFAKKNGGQFLLRLEDTDRARLVEGAVENLLSSLEWAGIIPDESPKHGGDFGPYVQSERLDIYKQYVQQLLDEKKAYYCFATPDELEESRQLQIKQGVQPKYNRKWLPEDMGGSMPQSEIQKRLDAGEPCVIRMKIPDHTRIRHDDIIRGIVWFDSSTVDDQVLMKSDGFPTYHLASVVDDHLMNITHVIRGEEWLSSTPKHLLLYDFFGWEKPEFAHLPLLLNPDRSKLSKRQGDVAVEDYMAKGYSKDALVNFVALLGWNEGEGVEQEVYSMNELIEKFTLEKVGKSGAVFNVEKLNWIQKQHLKLVSHEDLAKQAKAILVEKLKERESMMPSEKITDDAYLLNVVELMHDRVNFVHEFVTFSEYFFFEPEAYEEAAIKKRWKENTNDLLSEFKGILAGLDNFNSAAIEEALAKYAELKGVKNAALIHPIRLAVSGVSFGPSLYHLMEVIGKEACLRRIERAVDKLDYQEA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_RALPJ
Sequence: MSHFPKLLSSQIAFDVARTMLDGFDKHYRLFREVSVQAKTAFETGDWAGLQQLQRDRIAYYDERVREASVILEDEYDAENIDDEIWRQIKLHFIGLLTNHHQPECAETFFNSVCTRILHRSYFNNDFIFVRPAISTEYIENEESPTKPTYRAYYPGTRDGLGACFERIVHNFQLNAPFEDLERDIGYVVRAVGEHFGDFRIAPNFQIHVLSSLFFRNKAAYIIGRVINGDKTFPLAVPILRNAAGQLSLDTVLLRQEQLLILFSFTHSYFMVDMEIPSAYVTFLRDLMPRKPRAEIYTSLGLQKQGKNLFYRDFLHHLQHSSDKFIIAPGIKGLVMLVFTLPSYPYVFKVIKDYFPPPKETTRELIKSKYQLVKRHDRVGRMADTLEYSDVAFPLSRFDDDLIKELEKHAPSMVEYQRSEDGGEEIVIRHVYIERRMTPLNIWLHEGTDAQVEHGIIEYGNAIKELIAANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNIRTVPEPRTEEEEMSGEVWYNVGPHDIFPETYRTFLLGDPRVREAFLKHHADFFEASMWQGYKERLLSGQMHDFYAYDAAERFVNRYGASAPDNAAQDNTTLQRAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOR1A_RAT
Sequence: MKLGRATLALLLLVPCVVRAVEPISLGLALAGVLTGYISYPRLYCLFAECCGQKRSLSREALQKDLDNKLFGQHLAKRVILNAVSGFLSNPKPKKPLTLSLHGWTGTGKNFASKIIAENIYEGGLNSDYVHLFVATLHFPHASNITLYKDQLQMWIRGNVSACARSIFIFDEMDKMHAGLIDAIKPFLDYYDVVDEVSYQKAIFIFLSNAGAERITDVALDFWRSGKQREEIKLRDMEHALAVSVFNNKNSGFWHSSLIDRNLIDYFVPFLPLEYKHLKMCIRVEMQSRGYEEDEDIINKVAEEMTFFPKEEKVFSDKGCKTVFTKLDYYLDD
What is the function of this protein?
Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates.  Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN).  In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity.  Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission.  In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding.  May have a redundant function with TOR1B in non-neural tissues (By similarity).
What are the official names of this protein?
Torsin-1A, Dystonia 1 protein, Torsin ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Nucleus inner membrane; Peripheral membrane protein. Cell projection, growth cone. Cytoplasmic vesicle membrane. Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Peripherally associated with the inner face of the ER membrane, probably mediated by the interaction with TOR1AIP1. The association with nucleus envelope is mediated by the interaction with TOR1AIP2. Upon oxidative stress, redistributes to protusions from the cell surface.
Protein: PDEH_ECOLI
Sequence: MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRLMAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDFGTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL
What is the function of this protein?
Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of cyclic-di-GMP (c-di-GMP) (PubMed:18765794).  Part of a signaling cascade that regulates curli biosynthesis.  The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD (PubMed:23708798).  Effect on flagella is controlled via the c-di-GMP-binding flagellar brake protein YcgR (PubMed:18765794).
What are the official names of this protein?
Cyclic di-GMP phosphodiesterase PdeH.
Protein: PXPA_BACAN
Sequence: MTTIDLNCNLGESFGAYKMGNDDEILPFVSSINVACGFHAGDPSVMRQTVEKAMQHNVAIGAHPGFPDLIGFGRRNMNVSANEVYDYVLYQIGALDAFVKAAGGKMQHVKPHGALYNMAATNPEIADAIAKAIYHMNSSLSLYGLANSEAFIQAAEKYNITLVQEAFADRTYKEDGTLTSRTEENALIKNEDEAIKQVLQMVKEGYVNSVNGEKVAVQAQTICLHGDGEKAVQFARKIYRTFEHNKISICAPK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: PP110_ARATH
Sequence: MFRKTLNSISRRHFSSSSPESPSLYSFLKPSLFSHKPITLSPSLSPPQNPKTLTPDQKSSFESTLHDSLNAHYTDEAWKAFRSLTAASSLPEKRLINSLITHLSGVEGSGESISHRLKRAFASAAYVIEKDPILLEFETVRTLLESMKLAKAAGPALALVKCMFKNRYFVPFDLWGHLVIDICRENGSLAPFLKVFKESCRISVDEKLEFMKPDLVASNAALEACCRQMESLADAENVIESMAVLGVKPDELSFGFLAYLYARKGLREKISELENLMDGFGFASRRILYSNMISGYVKSGDLDSVSDVILHSLKEGGEESSFSVETYCELVKGFIESKSVKSLAKVILEAQKLESSYVGVDSSVGFGIINACVNLGFSDKAHSILEEMIAQGGGSVGIGVYVPILKAYCKEYRTAEATQLVTEISSSGLQLDVEISNALIEASMTNQDFISAFTLFRDMRENRVVDLKGSYLTIMTGLLENQRPELMAAFLDEVVEDPRVEVNSHDWNSIIHAFCKSGRLEDARRTFRRMVFLRYEPNNQTYLSLINGYVSGEKYFNVLLLWNEIKGKISSVEAEKRSRLDHALVDAFLYALVKGGFFDAAMQVVEKSQEMKIFVDKWRYKQAFMETHKKLRLPKLRKRNYKKMESLVAFKNWAGLNT
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g69290.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: GLUQ_BURCJ
Sequence: MNPGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGTWLVRIEDLDGPRTVPGAADDILATLAHFGMTPDEPPIWQSTRDAAYTAALERLVAAGLVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGNDAVVTFDDRWQHAQSQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPAYLHVPVVVDANGEKLSKQTGATALERDDPLPALRAAAAHLGLAADGDRPVHTIDAFYAAATDAWARRFGPRAG
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: TXAN1_ACANA
Sequence: IIECFFSCEIEKDGKSKEGKPCKPKGDKDKDKKCGGWRCKIKMCIKI
What is the function of this protein?
Is toxic to insects.  Reduces amplitude and frequency of spontaneous firing and inhibits voltage-gated sodium current (Nav) in the dorsal unpaired median (DUM) neurons of P. americana.
What are the official names of this protein?
Mu-theraphotoxin-An1a, Mu-TRTX-An1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 01 (Ap1a) subfamily.
Protein: NF03_NAEFO
Sequence: YAELKAILAKQIPEKQAXIN
What are the official names of this protein?
Unknown protein NF003 from 2D-PAGE.
Protein: PDCD4_PONAB
Sequence: MDVENEQILNVNPADPDNLSDSLFSGDEESAGTEEIKNEINGNWISASSINEARINAKAKRRLRKNSSRDSGRGDSVSDNGSDTLRSGVTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGDTNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTSDVEKSFDKSLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVPHSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
What is the function of this protein?
Inhibits translation initiation and cap-dependent translation.  May excert its function by hindering the interaction between EIF4A1 and EIF4G.  Inhibits the helicase activity of EIF4A.  Modulates the activation of JUN kinase.  Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.  May play a role in apoptosis.  Tumor suppressor.  Inhibits tumor promoter-induced neoplastic transformation.  Binds RNA (By similarity).
What are the official names of this protein?
Programmed cell death protein 4.
What is the protein family that this protein belongs to?
Belongs to the PDCD4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (By similarity).
Protein: MACA1_RHOOP
Sequence: MAERSSEFVFTGNPARVIFGAGRMRNVREEVERLGRGRVLLLGSENLREVCDQVQDLLGELFVNRYDGAAMHTPVEVTDIALAQLRTSEADCVVAIGGGSTTGLAKALAARTGVDQVILPTTYAGSEVTPVLGETVEGRKTTRSTLAVLPETVIYDVELSKNLPVPIAVASAVNALAHAVEAMYSPDANPVVDTWALEAAQALARGLRGLVSDPSCRRIRTDLLRGSWLAGMCLGSVGMAVHHKLCHTLGGAFGLPHAPTHTVVLPYAMSFNASEVPDVMDSLASAMNVSNAPAGVWDLIADAGGPTSLASLGLLQTDLDRAADLATEAPYRNPRQITRSGIRDLLQSAWEGNRPPE
What is the function of this protein?
Plays a major role in the degradation of chloroaromatic compounds by channeling maleylacetate and some of its substituted derivatives into the 3-oxoadipate pathway.  This enzyme converts maleylacetate and 2-chloromaleylacetate with similar efficiencies.
What are the official names of this protein?
Maleylacetate reductase 1, Maleylacetate reductase I.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: DNJB6_MACFA
Sequence: MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFEFFEDPFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSFGGGGMGNFKSISTSTKMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGKEQLLRLDNK
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity.
What are the official names of this protein?
DnaJ homolog subfamily B member 6.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Cytoplasm, myofibril, sarcomere, Z line.
Protein: SYD_EDWI9
Sequence: MRTNYCGQLNLSHVGQEVTLCGWVHRRRDLGGLIFIDLRDREGVVQVFFDPDHQDAFRQASELRNEFCVQVTGTVRARPESQRNSEMPTGEIEVFGHGLTLINRAEPLPLDFNQTNSEENRLKYRYLDLRRPEMAARLKTRAKITAFVRRFMDNHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMSAGQVREIMEALARALWMEIKGVDLGDFPVMTFAEAMRRFGSDKPDLRNPLELVDVADLVKSVDFKVFSGPANDARGRVIALRVPGGATLTRKNIDEYGQFVGIYGAKGLAWMKVNDRAAGMDGVQSPIAKFLNAEVLEGILARSGAQSGDIIFFGADSAKVATDAMGALRLKVGRDLQLTDESRWAPLWVVDFPMFEEDGEGGLAAMHHPFTSPRDISPEALKANPVGAIANAYDMVMNGYEVGGGSVRIHSGAMQSAVFDILGINEQEQREKFGFLLDALKFGTPPHAGLAFGLDRLVMLLTGTENIRDVIAFPKTTAAACPLTDAPSRANPAALQELSIAVCAKQGSDA
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.