PharMolix/UniProtQA huggingface dataset:
Protein: PTA_SYNY3
Sequence: MTSSLYLSTTEARSGKSLVVLGILDLILKKTTRIAYFRPIIQDPVNGKHDNNIILVLENFRLQQTYTDSFGLYFHEAVSLASDGAIDQVLDRILAKYRHLADQVDFILCEGSDYLGEESAFEFDLNTTIAKMLNCPILLLGNAMGNTIADSLQPIDMALNSYDQESCQVVGVIINRVQPELATEIQAQLEQRYGDRPMVLGTIPQDIMLKSLRLREIVSGLNAQVLSGADLLDNLVYHHLVVAMHIAHALHWLHEKNTLIITPGDRGDIILGVMQAHRSLNYPSIAGILLTADYHPEPAIMKLIEGLPDAPPLLLTSTHTHETSARLETLHPALSPTDNYKIRHSIALFQQQIDGEKLLNYLKTIRSKGITPKLFLYNLVQAATAAQRHIVLPEGEEIRILKAAASLINHGIVRLTLLGNIEAIEQTVKINHIDLDLSKVRLINPKTSPDRERYAETYYQLRKHKGVTLAMARDILTDISYFGTMMVHLGEADGMVSGSVNTTQHTVRPALQIIKTQPGFSLVSSVFFMCLEDRVLVYGDCAVNPDPNAEQLAEIALTSAATAKNFGIEPRVALLSYSSGSSGQGADVEKVRQATAIAKEREPDLALEGPIQYDAAVDSTVAAQKMPGSAVAGKATVFIFPDLNTGNNTYKAVQRETKAIAIGPILQGLNKPVNDLSRGCLVEDIINTVVITALQVK
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_GLOVI
Sequence: MTQSLLLDAARSKPVARPPVWMMRQAGRYMAEYRALRDKYGFKERCENPDLAVEISLQPFRAFRPDGVIMFSDILTPFDGMGIPFELVESRGPVIDPPIRTREQVEAVRPLDPEASLAFVRTILQTLRREVGEAATVLGFVGAPWTLAAYAVEGKSSKDYALIKQMAFSEPDLLHALLTKFADAIARYVIFQIDSGAQAVQLFDTWAGQLNPADYRAFALPYERRIVEQVRQVHPETPLILYINHSAGLLRHVGESGVDVMSLDWTVDMAEARAILGPDMAVQGNLDPCVLLGDQAQIRSRILDIVEKAGPTGHIMNLGHGILPSTPEDNARFFFETVKSLAPVSAR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM6_SCHPO
Sequence: MMPSSSFQQTPKPVDLDDPRFEQYDCLPCRLVGAGAFTGLGIYAYSQSRIPLNTPNYKLKRFGILGMAYGFILTGVYRLFQ
What are the official names of this protein?
Uncharacterized protein tam6, mitochondrial, Transcripts altered in meiosis protein 6.
What is the protein family that this protein belongs to?
To yeast YDL157C.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ESFL4_ARATH
Sequence: MKSSHAYLVCILLLSLFSLHQCVRLERSNKIDMSVCVHEICGGVFDGGCYCCPKTPALCWADIQFCTTYCQSQT
What are the official names of this protein?
EMBRYO SURROUNDING FACTOR 1-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: GCH1_MUCPU
Sequence: FSMCEHHLLPFIGKAHVAYIPNGKVLGLSKVARIVDMYARRLQIQENLSRQIAEAVEQVTGALGVAVVIEAQHMCMVMRG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: 1001R_ASFWA
Sequence: MVRLFRNPIKCIFYRRSRKIQEKKLRKSLKKLNFYHPPEDCCQIYRLLENVPGGTYFITENMTNDLIMVVKDSVDKKIKSIKLYLHGSYIKIHQHYYINIYMYLMRYTQIYKYPLICFNKYYNI
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: TRM1_HALSA
Sequence: MDVSEGGVTVSVPTASGGGEGAADDVFFNATQELNRDLTVATLAAFREREPRAASYLDAMTASGIRGVRAANAGWDVTMADVDADAVELATSNLARNGLDGEVVARDANSLLHDHDRVLDVVDIDPFGSPMPFADAAFANARNLVCVTATDTAPLCGAHFESGVRKYSATPRNTNYHAEMGLRILLGALARTAARYDVGVTPILSHVSDHYVRTYLELDHRATDANAAVEQVGHVYHCQQCLSRDHEYGLVAAPRAECPRCGGHQVLTAGPLWLGPAHEEAFAASVREQLTREMGEASQAFHLLQTIEGELHEPTHYDQHRLYSQWGEPAVGMAEFLDQLRDAGLRASRTHFGGTTFKTDGGLAEVEAAVL
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: IXTPA_CHLFF
Sequence: MKIVIASSHGYKIRETKTFLKQLGSFDIFSLADFPDYYAPKEIGSLPEDNALAKGLHAAKELNSWVIADDTMLMVPALNGLPGKFSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYFECCVVLASPEGKFFKSRGICEGYISNHEKGSSGFGYDSLFLKYDYKQTFAELSEDVKNQVSHRAKALQKLTPYLQDLLEKHLVSRN
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: HASC2_STRP3
Sequence: MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATIAVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase 2, Alpha-D-glucosyl-1-phosphate uridylyltransferase 2, UDP-glucose pyrophosphorylase 2, UDPGP 2, Uridine diphosphoglucose pyrophosphorylase 2.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: ZCHC3_HUMAN
Sequence: MATGGGAEEERKRGRPQLLPPARPAARGEEADGGREKMGWAQVVKNLAEKKGEFREPRPPRREEESGGGGGSAGLGGPAGLAAPDLGDFPPAGRGDPKGRRRDPAGEAVDPRKKKGAAEAGRRKKAEAAAAAMATPARPGEAEDAAERPLQDEPAAAAGPGKGRFLVRICFQGDEGACPTRDFVVGALILRSIGMDPSDIYAVIQIPGSREFDVSFRSAEKLALFLRVYEEKREQEDCWENFVVLGRSKSSLKTLFILFRNETVDVEDIVTWLKRHCDVLAVPVKVTDRFGIWTGEYKCEIELRQGEGGVRHLPGAFFLGAERGYSWYKGQPKTCFKCGSRTHMSGSCTQDRCFRCGEEGHLSPYCRKGIVCNLCGKRGHAFAQCPKAVHNSVAAQLTGVAGH
What is the function of this protein?
Nucleic acid-binding protein involved in innate immune response to DNA and RNA viruses (PubMed:30193849, PubMed:30135424).  Binds DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as RIGI, IFIH1/MDA5 and CGAS (PubMed:30193849, PubMed:30135424).  Acts as a co-sensor for recognition of double-stranded DNA (dsDNA) by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and DNA virus (PubMed:30135424).  Binds dsDNA and probably acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation (PubMed:30135424).  Promotes sensing of viral RNA by RIGI-like receptors proteins RIGI and IFIH1/MDA5 via two mechanisms: binds double-stranded RNA (dsRNA), enhancing the binding of RIGI and IFIH1/MDA5 to dsRNA and promotes 'Lys-63'-linked ubiquitination and subsequent activation of RIGI and IFIH1/MDA5 (PubMed:30193849).
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y232_STRT1
Sequence: MTSLLITGYKSFELGVFKDKDPKVNIIKKAIKRDLKRFLDEGVDWMIFTGNLGFEFWALEVAKELQKDYPLRLATLFPFKTHGQNWSEANQEKLAAFKQVDFVKYSFPAYQSPAQFKQFNQFLIDNTDQAYLFYEPENETNLKYFYNMIIAASDYPLFRLTFDDLNEVMSE
What are the official names of this protein?
UPF0398 protein str0232.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: CBIA_METVS
Sequence: MKRVVIAGTSSMVGKTTISTGIMNALSKKNNVQPYKVGPDYIDPTYHTKATENTSRNLDSFFMDETQIRSLFKRHSQNKDISIIEGVRGLFEGISPYNDVGSTASVAKTIDSPIILLMDARSLTRSAAAIIKGFKSFDSELNIKGVIFNKIRGDGHLNKLKEAVKYYDGEIEIVGAIKRDENLAVAERHLGLVPTPEKTEELGKQIEFWGDTVLECLDIDKIIEISDVDFEIPVDNKNKDETLWKVDKNSSKIAIAFDESFNFYYHDNFDALKENGAKLEFFSPIHDFEIPNCDILYLGGGYPEIFSKELSKNTSMIESIRNFDGKIYGECGGLMYLTNSINGVDMLKLINADSIMTKNVQGLSYVIGSFKKDCIIGKEKETFKAHEFHYSKLININENDFSYEINRGTGIIDKLDGISIKDGRIVGGYAHQHAVGNPYFASCLSKL
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase, Ni-sirohydrochlorin a,c-diamide synthase, Ni-sirohydrochlorin a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: SCHI1_HUMAN
Sequence: MERSGQRVTTWDCDQGKHSDSDYREDGMDLGSDAGSSSSSSRASSQSNSTKVTPCSECKSSSSPGGSLDLVSALEDYEEPFPVYQKKVIDEWAPEEDGEEEEEEDERDQRGYRDDRSPAREPGDVSARTRSGGGGGRSATTAMPPPVPNGNLHQHDPQDLRHNGNVVVAGRPSCSRGPRRAIQKPQPAGGRRSGRGPAAGGLCLQPPDGGTCVPEEPPVPPMDWEALEKHLAGLQFREQEVRNQGQARTNSTSAQKNERESIRQKLALGSFFDDGPGIYTSCSKSGKPSLSSRLQSGMNLQICFVNDSGSDKDSDADDSKTETSLDTPLSPMSKQSSSYSDRDTTEEESESLDDMDFLTRQKKLQAEAKMALAMAKPMAKMQVEVEKQNRKKSPVADLLPHMPHISECLMKRSLKPTDLRDMTIGQLQVIVNDLHSQIESLNEELVQLLLIRDELHTEQDAMLVDIEDLTRHAESQQKHMAEKMPAK
What are the official names of this protein?
Schwannomin-interacting protein 1, SCHIP-1.
What is the protein family that this protein belongs to?
Belongs to the SCHIP1 family.
Protein: RS14_PROA2
Sequence: MAKKSVIARNEKRKALVEKYAAKREELKNAGDYEALSKLPRNSSATRVRNRCVLTGRGRGVYEKFGLCRHMFRKLALEGKIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: VKT1_HOPST
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPEFCELPADPGPCNALSQAYYYNPVQHKCLKFRYGGCKANPNTFKTIEECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor stephenin-1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: HABP4_MOUSE
Sequence: MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAASGAGHRGGRSPAVASGHRPGAGGRRESQKERKSLAASGAQQPDSPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLERAERRSYREYRPYETERQADLPVEKFTDEKPVDRFDRDRPLRGRGGPRGGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKTNRMEDSMGGCGIRPWGSGKDTSDTEPPAPMEETSMMEECQGTLDEESAAKVPELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDMVKEDYEDESHVFRKAANDITSQLEINFGNLPRPGRGARGSTRGGRGRMRRTENYGPRAEVVTQDVAPNPDDPEDFPALA
What is the function of this protein?
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation.  Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress.  Plays a role in pre-mRNA splicing regulation.  Binds (via C-terminus) to poly(U) RNA.  Involved in mRNA translation regulation, probably at the initiation step.  Seems to play a role in PML-nuclear bodies formation (By similarity).
What are the official names of this protein?
Intracellular hyaluronan-binding protein 4, IHABP-4, IHABP4, Hyaluronic acid-binding protein 4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, sarcoplasm. Nucleus, nuclear body. Nucleus, nucleolus. Nucleus speckle. Nucleus, Cajal body. Nucleus, gem. Note=Transported into the nuclear compartment in activated leukocytes. Inhibition of methylation alters its distribution between the nuclear and cytoplasmic compartments. Methylation may be required for its localization in subnuclear structures, such as nucleoli, nuclear speckles, Cajal bodies and Gemini of coiled bodies (gems). Colocalizes with FMR1, FXR1 and FXR2 in cytoplasmic stress granules. In myocardial cells, localization at the sarcoplasm is reduced in response to mechanical stress.
Protein: RNPH_BURCH
Sequence: MTSSVSRPSGRRADELRKVALTRHYTKHAEGSVLVEFGDTKVLCTASVAERVPEFLRERGQGWLTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRALRAVFDLEALGPRTIHIDCDVIQADGGTRTASITGAFVAAHDAVSTLIAAGKLARSPITDHVAAISVGVYEGAPVLDLDYAEDSRCDTDMNVVMTGAGGFVEVQGTAEGVPFSRAEMNALLDLAQGGIAELVQLQKDVLGASHA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL6_SHIB3
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YVH1_PLAF7
Sequence: MIVKVFDYIYISNVYNANDIYELIKLNIGGVLTCFDCTCIEWCHHNDTNVTNKIFYKDIFVNTKKDLIKCDVPIITNKSVNSDIIGGTHQINNYYNEQNNNYHDNTYKEFTQTHKTNIDPSQIKSDHINEERKEHYDYIIFPSDIINNTQCNNNNLKDYIKSMLILKEDAYIDFDVIHMDQLKNKHNNNNNNNNNNNNNNNNNNNNNNCCTFKNPDISNTSQHHVEHIQIHKSNSHSNIPSDNINFCNKKYDKNLSRSVEISEKDKHPENSLLYEFVNKDKLNYKINQEEDTVSSEKNKLCDNNNNNNMVHTRHIYNVCELNKCLRENKLIPYNNIYKMKHLYLNILDTFDENILKHVNKAHLFIDSVIQKKKNILIHCMAGISRCSSIILSYVSKKNKKGIEYNFNLLKSKYPFAHPNENFYRQLLLYEKMNYTLDGCTDYHNIYKKIKMNRENLEELKILNLKNDKQPIYNFRCKHCNYVLFNDNEIIKHDFKISKIKKNYGNSCTSIFIEKKEWILTENKMKGVLNCPNVNCNIKLGKWSWTGICCSCGYLQIPAFMINSSNVDRMNISKTV
What is the function of this protein?
Dual specificity protein phosphatase which dephosphorylates both phosphotyrosine and phosphoserine residues.
What are the official names of this protein?
Dual specificity protein phosphatase YVH1, PfYVH1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm at the ring stage, translocates to the nucleus in the trophozoite stage and returns to the cytoplasm at the schizont stage.
Protein: THIE_CLOBH
Sequence: MEINYELYLITDRRFLKGRQLKKVVEDAILGGVTIVQVREKDVSTREFYNVAKEVKEVTDYYKVPIIINDRLDIAQAIDASGVHLGQKDMHLNIAREILGKDKIIGISVGNVKEALQAQNNGADYLGIGTIFPTGSKKDVDAIIGIDGLSKIKDSISIPSVAIGGINKTNFKDVLKTGIEGISVISAILDEDDIKLAANNLLINK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PEN4C_PENVA
Sequence: MRLVVCLVFLASFALVCQGYSSGYTRPLPKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHRG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-4c, Pen-4c.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: HIF1_YEAST
Sequence: MKLRAEDVLANGTSRHKVQIDMERQVQIAKDLLAQKKFLEAAKRCQQTLDSLPKDGLLPDPELFTIFAQAVYNMEVQNSGNLFGDALLAGDDGSGSESESEPESDVSNGEEGNENGQTEIPNSRMFQFDQEEEDLTGDVDSGDSEDSGEGSEEEEENVEKEEERLALHELANFSPANEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLGRPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKALGYYKTLKPAEQVTEKVIQAEFLVCDALRWVDQVPAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQDDIDEVQENQQHGSKRPLSQPTTSIGFPALEKPLGDFNDLSQLVKKKPRRH
What is the function of this protein?
Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex.  Involved in chromatin assembly and telomere silencing.
What are the official names of this protein?
HAT1-interacting factor 1.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
Protein: ARP6_CRYNJ
Sequence: MATPPVLIIDNGAYEIKAGISGVDWEPRVLPNSIARSRTEKRVYVGDEIDNCKDLSGIVYRRPFEKGMLVNWDAERIIWDRLFSPSVLNINPTETSLLVTEPYFNLPNIAETYDQMIFEEFEFQSYFRCAPAALIPYGGLYESDQGIPPQCTIVIDMGYSYTHVVPIRDGQIVWEHVKRIDVGGKLLTNHLKHLISFRQWNMIDQTHVVNSVREACGYVSLNWKGDLETCKAKPRKNPIIQEYVLPDFSANSTSRTGYIRSGPNAAPPEETNGTGEVNGKQKPEEEEQVLWMGNERFAGPELLFHPSDIGLKQTGLPETIAYVISQMPEELRGMFWAHIGIIGGLGNIENLGERLERDLQALCPVEYEIGIYEAFDPASLAYTSATALTSSEVYMSTYPVTRTEYFEQGSSLCRRKFGSFGAPAYNIDPPGFSSGVDARTEVSDDEMEMRYAMGLESKKGGKGKRRKEEEEVTSGNWGGRRRRTTGLGGF
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Actin-like protein ARP6.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus.
Protein: SPG4_LACTC
Sequence: MGGIFDAFEVYNKKKHSSNPHMFGNTSNTGGTKTDYVYSSEYRAPKKNKLMKDELLAPDSEHADGAKAMLTESAAQAGTPNMVDLSKLSQHELESLMKDLRKGEPNNRVNF
What is the function of this protein?
Stationary phase-essential protein not required for growth on nonfermentable carbon sources.
What are the official names of this protein?
Stationary phase protein 4.
What is the protein family that this protein belongs to?
Belongs to the SPG4 family.
Protein: SECA2_STAAC
Sequence: MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PUR9_MICAN
Sequence: MGRLALISVTDKTGIVDFARQLTEEFDFEIISSGGTAKTLQSAGIPVIKVGEYTGSPEILGGRVKTLHPRIHGGILARRDWQSDLAEMEANQIRPFDLVVVNLYPFEQTIANPDVTTAQAIEQIDIGGPAMLRASAKNFAHLTVISNPKYYEQYLSQLRQNNGEISLEFRQKMAGETFALTNAYDGAIAAYFASLNGETTRFNLAGNALQTLRYGENPHQSATWYGSGTMAQGWGKATLLQGKELSYNNLVDLEAARRLIAEFGSEEPAAAILKHTNPCGVAIGGSLVEAYTKAFNADAISAFGGIVALNQAIDEATAKELTKTFLECVVAPDCSPEAQDILAKKSKVRILLLPDLTTGEKQTVKVIAGGFLVQAADDVVETPDEWRVVTEKQPTPAQLAELLFAWKVSKHVKSNAIVVTKNQTTLGVGAGQMNRVGSVKIALEQAAEAAKGGYLASDGFFPFDDSVRTAAQFGIEAIVQPGGSLKDQDSINAANELGLIMVLTGIRHFLH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: HIS7_BACHK
Sequence: MRESSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHAANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_VIBVY
Sequence: MKAVVLGSGVVGLMSAWYLQKSGYQVTVVDRQARSAEETSFANAGQISYGYSSPWAAPGIPQKALRWLMEEHAPLKIKPSLDPQLLKWATQMLANCQLSRYQVNKARMLAIANHSRECLSQLRQEHDIEYQGRQQGTLQIFRTQKQLIAIEKDIALLEQSGTRYQRMSVDECIKQEPGLAAVSHKLTGGLYLPDDETGDCYLFCQQMTELAQQQGVTFLFNTNVKKVNAQGNQVVSVSTDAGELQADVYVVAMGSYSTALLAQLGITIPVYPVKGYSLTVPITDESQAPVSTVMDETYKVALTRFDDRIRVAGTAELAGFDPAIPEKRKATISMVVNDLFPHSGDFAKAEFWTGFRPMTPDGTPLIGKTPLKNLYTNTGHGTLGWTMACGSGHLLSQIITGEQSENQAGLDLFRYAS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: CLU_ASPFC
Sequence: MAIWSTRKVGLDNLRISQLLNFRGFDPSALVTKLTDPFSLQRLLTLNQSRSPPMVNRLKDSRKRRAAVVCRIRDTRDGWFSSLSSLTSSVIGLFQISVKLPHEPYKIQVMVSSQEQVQDVRQSIVELPSTFQYTCFHLEFNGKRINDFVELSEVEGLKADSEIVLVEDPYTEKEARMHVVRFRDLVGAAGDRSDNLHGLNAGLSLHDAVTAEAATDDVKEHSLSKYDIAASPSLETILPRAEAPLPKTVKSISLSAWNPPPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFYVNKCSNHKFDPLPRTTPKKVSAHSLLTLISKLSPSFNSAFEALQESNNKKDLLTTFPFQNAIPNSPWLVTPPSSNPNSHQADITRSQESYLVSGVDNAETLRDWNEEFQTTRELPRETVQDRVFRERLTSKLFADYNEAAARGAVLVARGEVAPLNPTEERDAQIFVYNNIFYSFGADGVGTFVSEGGDEAARVAVGKDVLGIKAVNQLDINGLFTPGTVVVDYLGKRIVGQSIVPGIFKQREPGEHQIDYGGVEGKDVVATHPDFVSVFEKMSKALRIKKHPVWDKEGKRHDLEGSVETKGLLGTDGRKYVLDLYRVTPLDVVWQEEPGSEDYPHRMSVLRLELVEAYWRSKMSQYVKAEVERRRAAKAQEDAANKEQPSETTESKEGESEEKAEEALDQERVDISGFQLALNPDVCSGQVPQTEEEKKQWAEDEKEVRDACEFLRSKVIPELIQDLHDGDVGFPMDGRSLSQLLHKRGINIRYLGKLAQLSKEKGSRLEALTTLLVQEMIARAFKHIANRYLRNVPAPFVASCVAHLLNCLLGADVNPKPSAEIDASLREIYPEGDFSFEKVTPETLRAEVEKQVTVRYRYTLETEWFSSLRHLQLLRDIAIKLGLQLGARDYAFTKAQLPAKVPVANGVNGASHDESKKKKKKGGDSKSPSRAVVEEKPVVSIVPDDIVNVVPLVKDASPRSSLAEEALEAGRISLMQNQKQLGQELILESLSLHEQIYGILHPEVAKLYHQLSMLYYQTDEKEAAVELARKAVIVTERTLGVDSADTILAYLNLSLFEHASGNTKTALVYIKHAMDLWKIIYGSNHPDSITTMNNAAVMLQHLKQYSDSRKWFEASLAVCESLFGKQSINTATILFQLAQALALDQDSKGAVGKMRDAYNIFLNQLGPNDRNTKEAETWLEQLTQNAVSIAKHAKDIQARRLRRINMNPRVTTLGTKVQPQVGQTAPEASGAKGAANASMDSRSIDELLKFIEGGDATSSRSKQKKRAAASNPKLRGSKKSSA
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.