PharMolix/UniProtQA huggingface dataset:
Protein: METE_COXBU
Sequence: MVYAHNLGFPRIGIKREMKKTVEAYWRGEISQQQLQQQAIELQLTNWKIQAEAGVDLIPVGDFSWYDHVLDMAVRVGAIPSRFKALNSNITDTMFCMARGQAPNGIETSACEMTKWFDTNYHYIVPEFTTNQSFELHHDDLFKSTKLALENNYRAKPVILGPLSFLWLGKCKGESFNKLLLLEKLLPVYAEIFEQLSSLGVEWVQVDEPILVLDLPPEWQQAFLTTYQQLNFFNLKCLLATYFGSLDDNLSLTCQLPVDGLHIDYCRAPDQLDSVLSQLPAEKILSVGIIDGRNIWCNDLNRSLTLLENIQSSLGDRLWVAPSCSLLHVPIDLDQENKLDVELKSWFAFAKQKVAEAAFLTRGLREGRESIGAELKKNEEVIISRKTSKRIHNPNVEKKAASVTERLMRRQHEHSIRKNKQTAQLNLPLFPTTTIGSFPQTSQIRCLRRDYKQGKIDDALYEEKIRQEIAEVIGIQVKLGLDVLVHGEPERNDMVEYFGELLDGIAITSNGWVQSYGSRCVKPPIIFGDVSRERPMTLRWIEYAQSLTTKSVKGMLTGPVTILAWSFVRDDQPRSQTAKQIALALRDEVQDLERSGVRVIQIDEPAFRECLPLRKAAWQDYLEWAVKCFRLASCGVKDETQIHTHMCYSEFNDIIEAIAALDADVITIESSRSEMEILKSFEKFAYPNDIGPGIYDIHSPRIPRVAEIEELAVRALQYIPIERLWINPDCGLKTRNWEETKEALSRMVDAAKHLRKAFSSEKTPTIDLELQPAST
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: MIAB_KLEP7
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTEVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGDHIRQRAHYVDIIFGPQTLHRLPEMINSVRGNRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPCDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLREARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEADKKQRLYILQERINQQAMAWSRRMLGTVQRILVEGTSRKNIMELSGRTENNRVVNFEGTPDLVGKFVDVEIVDVYTNSLRGKIVRTEAEMGLRIAESPESVIARTRKENDLGVGIYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_STAAB
Sequence: MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: VHS1_YEAST
Sequence: MMMFHNCRINNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLAKLFKESKNVVRVPSIDLESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAVCTFIVMDYYPTDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTEDNVFLCDFGLSTTSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLWSLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILPLSDDFYSLLSKILQVNPKNRMSLQELMKEVSSITSFTNEGPLSKVPPLSKSVYEKFVSPVDNTNENLSPKSYVYMHDSKAAKNLSYTSSSEEEDGIKEGIDDDNGSRSGSFGTLDTDTGLHSSFTSTSCESDNECSKISNKFSLFEKKFNELRMSSSSLTN
What is the function of this protein?
Probable serine/threonine protein kinase involved in the G1-S transition.
What are the official names of this protein?
Serine/threonine-protein kinase VHS1, Viable in a HAL3 SIT4 background protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_THIDA
Sequence: MTVHTAAEKAYILSEALPYIQRFYDKTIVIKYGGNAMTERHLMEAFAKDVVLLKLVGMNPVVVHGGGPQIAGLLQRIGKQSEFIQGMRVTDEETLDVVEMVLGGLVNQDIVTLINKHGGRAVGLTGKDGNFIHAKKMLVKSKEKADEMLDIGQVGEITGIDPEIIQVLDARDFIPVVAPLGTDAEGNAYNINADVAAGKIAGVLQAEKVIFMTNTPGVLDKDKKLLTGLTPREISDLIADDTISGGMIPKVGYAVDAVNSGVKTAHIIDGRVEHALLLEVLTPEGVGTLIKRS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_STAS1
Sequence: MAGGPRRGGRRRKKVCYFTANGITHIDYKDTELLKRFISERGKILPRRVTGTSAKYQRMLTLAIKRSRHMALLPYVKEEQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LPXK_CHLAB
Sequence: MKTRFPSPFFIFYRRLTVAISLGKILGWGCFGKLLSWIFAATVSFRRKVLSSAPHRVSSTVISVGNIVLGGSGKTPTVLWLAEVLKARGYSCAILSRGYKGKCSGQRKLTIVDPEIHDAAYVGDEPLLMAGKLSKGAVFVHKDRRLAAKEVAKNFDILLLDDGFQNNKLHKDVEIVVVNGQDPLGGGAFFPRGRLRDSPKRLQEADFIIVNGSCGLENQKLLHTWCTSPKIFVEPRISQVLWDSRGEKLPLDSLSGLAAGVFCGLGFPQGFLDMLKRAGVKIVGTYLLPDHAGITKKELHYFSSMTAMRQGEGILCTEKDGIKLGNLIHEPGILPIGKVQMEFDFTHQEDATAALLDKIDRIHNGKR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: URE3_STAA9
Sequence: MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPDGTKLITVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_ECOBW
Sequence: MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTNCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RL17_KOSOT
Sequence: MRHRVKKKKLNRPHSQRLALMRGLARELFEHGTIITTTAKAKAVKPFVESIITKAKKAALYAKEINERSNGDPEIQALRSKNVALRREINRHFNDRKLVKKICDEIAVNYIDRNGGYTRIIKVGRRRGDAAELSILQLVETKSEENVEN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AROD_STRR6
Sequence: MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: MINE_SALDC
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: ZNUC_SHIBS
Sequence: MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDILPALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFGPRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MUTL_TOLAT
Sequence: MPIQILPPILANQIAAGEVVERPASVIKELVENSLDAGANRIDVELEKGGCQLIRVRDNGGGICGTELALALARHATSKVATLDDLEHIASLGFRGEALASISSVSRLTLTSRTAGQHEAWQAYAEGREMAVTVKPAAHPVGTTVEVLDLFFNTPARRRFLRSEKTEFAHIDELLRRLALSRFDVAINLKHNGKLLRQYRPAQTESQQEQRVVQACGAEFMQAALRIDSEHLGLHLYGWLAPQPLTAINEVQYCYVNGRMIRDKLLNHAIRQAYSECTGTSFQPAYILYLELDPHQVDVNVHPSKHEVRFHESRQVHDFIVQVIRQALQTAYSENAPDAVFSGIEDAAPDYPVSPLKNRATGQHQYSAPTGGYSSPSGSQLRSYGQLLTSELPSIPVSREAGSVAAPDNSDWPVLRLIQQRYLLSAQDDTLYLSDLVAIQSLQWLTQCNASFNEGLIAQPLLIPQRLDIARPHEWLAEYGIWLQKLGLRYNTHKNKQIIIQAVPALLRQTDMASTIPAMLSLLERYPVALSHQEWHSFIATWLKLPGLIPHHYSMDSARSLWLWLQQNVADWQNNTQLMRSVDLTNILEVFSRD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: UNG_BORBR
Sequence: MPNDNRLAPAALAAQAAALPAAWRHVLEQPAVARAFASVLGHVEQRLAEGAVVYPATPFRALDQLAPADVRVVILGQDPYHGPGQAQGLAFSVPDDCKCPPSLRNIFNEIAVDYPRPTRHDLSAWTRQGVLLLNTSLTVEDGQPGSHAKRGWETVTDALIAEVARDPSPKVFLLWGAHAQAKQALVPADAGHLVLAANHPSPLSARRPPVPFVGCGHFRQTNAWLQQRGQKPVDWSGEQNNASRQGKFAL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM267_XENLA
Sequence: MASEMEKADALLHTFSTASAFSSLGLGLFCFVADRVQQATFIQQHDWLRALSDSTTHCVIGMWSWAIVIGLRKRSDFCEVALAGFFASIIDLDHFFLAGSVSLKAATNLQRRPPLHCSTLIPVVALALKFLMQLLRLKDSWCFLPWMLFISWTSHHVRDGIRHGLWICPFGNTAPLPYWLYVVITASLPSVCSLIMCLTGTRQLMTTKHGIHIDV
What are the official names of this protein?
Transmembrane protein 267.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARCA_MYCBT
Sequence: MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSGAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMGIDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL_LACLA
Sequence: MAMMTMIDVLERKDWENPVVSNWNRLPMHTPMDLLEKQSLNGLWNFDHFSRISDVPKNWLELTESKTEIIVPSNWQIEFKDKSDVPIYTNVTYPIPIQPPYVPEANPVGAYSRYFDITKEWLESGHVHLTFEGVGSAFHFWLNGEYGGYSEDSRLPAEFDISNLAKEGQNCLKVLVFRWSKVTYFEDQDMWRMSGIFRSVNLQWLPDNYLLDFSIKTDLDEDLDFANVKLQAYAKNIDDACLEFKLYDDEQLIGECHGFDAEIGVVNPKLWSDEIPYLYRLELTLMDRSGAVFHKETKKIGIRKIAIEKGQLKINGKALLVRGVNKHEFTPEHGYVVSEEVMIKDIKLMKEHNFNAVRCSHYPNDSRWYELCDEYGLYVMDEANIETHGMTPMNRLTNDPTYLPLMSERVTRMVMRDRNHPSIIIWSLGNESGYGSNHQALYDWCKSFDSSRPVHYEGGDDASRGATDATDIICPMYARVDSPSINAPYSLKTWMGVAGENRPLILCEYAHDMGNSLGGFGKYWQAFREIDRLQGGFIWDWVDQGLLKDGNYAYGGDFGDKPNDRQFSLNGLVFPNRQAKPALREAKYWQQYYQFELEKTPLGQVFAFTVTNEYLFRSTDNEKLCYQLINGLEVLWENELILNMPAGGSMRIDLSELPIDGTDNLFLNIQVKTIEKCNLLESDFEVAHQQFVLQEKINFTDRIDSNEEITLFEDEELLTVRSAKQKFIFNKSNGNLSRWLDEKGNEKLLHELSEQFTRAPLDNDIGVSEVEHIDPNAWLERWKGIGFYELKTLLKTMIIQATENEVIISVQTDYEAKGKIAFSTIREYHIFRNGELLLKVDFKRNIEFPEPARIGLSLQLAEKAENVTYFGLGPDENYPDRRGASLFGQWNLRITDMTTPYIFPSENGLRMETRELNYDRLKVRAMGQSFAFNLSPYSQNQLAKKGHWHLLEEEAGTWLNIDGFHMGVGGDDSWSPSVAQEYLLTKGNYHYEVSFKLT
What are the official names of this protein?
Beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: VG17_ICHVA
Sequence: MIPPGIPVVQLSFPIGSRIRSISVPTGTHNALDRILSRPSPKMKFTDYLNGALACGVAGAAYKALDNFGWGRVSAVIGGVTVGLCAAFGPKKITELNALSDQMLAEATEDIKRERLTKALSTFTILAASRAPINTWTTRPRERFDALTGIPARWDDALCEMEFDRTCGSGERGLHALHALSGVIVGELERLLVEGHVSTDLAQVYLTMLIVTLFRDDEFGRALLKVDSIILALESRIDTVRLEEIQRVMCASVTRFHGVRPGFETEAFAKMHDAINRCGLYGTARGEPSEVEEPGSTV
What are the official names of this protein?
Uncharacterized protein ORF17.
Protein: MIC60_SCLS1
Sequence: MLRAGLRSSRALGLRPNVVSPGRQWRAQNARVISDTMRTFADKSSISDSRPPVLPGSASEATSEPLPPGAVATPNSAAPTPATPTSSTIPAENVPLTPPPPGVQSPGPPPPSSSPPPPAPKPKRRFFRKFFTTLFLLTTLGFGGGVYYSRINDNFHDFFTEYVPFGEDAVLYFEEQEFRKRFPLISSRASRPPRDTGEQVKIPSQSGVSWRVANENKDSTGRHTSSAKDKVKPSEAVQTPHDSKPADRVKAVEQVKSGNSPVKNSPAPPATPESKPSNVQKDPEVNEPSRAYKKIERIDPINIPNGNEPVVQELVKIMNDIIAVVNADNANARFTSTMDKAKAELNRVGAKILDMKDAALKQADEKIKSSDAEFDRAAMQLMQNFKNQQAEQEAQFRAEYEAERKRIHENYEQKLKSELDRANEVNEKTLQNNLTEQALELKRAFLADVKNRVEQEREGRLGKLSELTSTVNDLEKLTGDFNTVVDQNLKTQHLHVAVEAVRANLEKSQIPRPFTRELAALKEIASDDPVVNAAIASINPVAYQKGVPSSAALIDRFRRVASEVRKASLLPEEAGVASHASSYVLSKLLFKKKGLATGDDVESILTRTETFLEEGDLDGAAREMNGLKGWAKTLSKDWLGEVRKVLEVQQALDKPDYKV
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit mic60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLMM_FUSNN
Sequence: MGRYFGTDGIRGEANRELTVDKALRLGYALGYYLKNNNPNEEKIKVIMGSDTRISGYMLRSALTAGLTSMGIYIDFVGVIPTPGVAYITKQKKAKAGIMISASHNPAKDNGIKIFNLEGYKLSDEIENQIEDYMDNLDKILANPLAGDKVGKFKYAEDEYFQYKNYLTQCVKGNFKDIKIVLDTANGAAYRAAKDVFLDLRAELVVINDAPNGRNINVKCGSTHPDILSKVVVGYEADLGLAYDGDADRLIAVDKFGNVIDGDKIIGILALGMKNKGTLKNNKVVTTVMSNIGFEKYLKENSIELLRANVGDRYVLEKMLAEDVVIGGEQSGHIILKDYATTGDGVLSSLKLVEVIRDTGKDLHELVSSIKDAPQTLINVKVDNIKKNTWDKNEIIMSFINEANKKYKDEVRILVRKSGTEPLIRVMTEGDDKQLVHKLAEDIAHLIEKELN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GREA_CHLP8
Sequence: MSDRIYLTRDGYNRLKEELHLLSTQTRKEVLEKIAEARSHGDLSENAEYDAAREEQSQLEAKIGDLENKLASATILDPKQIKTDRVYILTSVKLRNLDDEDEIIEYTLVSSEEADSDLGKISVRSPVGRALIGKSVGDKVTISVPKGELHYEILDIFVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: YQEC_ECOLI
Sequence: MKSIVDPSALVIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQASGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFTPEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHTLGAKVSTENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQCENAIAQSELLQPLQQHDVEAIWLGDIQEHPAIARRFVN
What are the official names of this protein?
Uncharacterized protein YqeC.
Protein: MMP16_HUMAN
Sequence: MILLTFSTGRRLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYGYLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTDRVKEGHSPPDDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCKRSMQEWV
What is the function of this protein?
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin.  Activates progelatinase A.  Involved in the matrix remodeling of blood vessels.  Isoform short cleaves fibronectin and also collagen type III, but at lower rate.  It has no effect on type I, II, IV and V collagen.  However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
What are the official names of this protein?
Matrix metalloproteinase-16, MMP-16, MMP-X2, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
[Isoform Long]: Cell membrane; Single-pass type I membrane protein; Extracellular side. Note=Localized at the cell surface of melanoma cells. SUBCELLULAR LOCATION: [Isoform Short]: Secreted, extracellular space, extracellular matrix. Cell surface. Note=Localized at the cell surface of melanoma cells.
Protein: FADJ_SHEPC
Sequence: MEKTFNLTRRDDGIAILTMDVPGETMNTLKAQFGPEISEILAEIKSDPHIRGLVLISGKKDSFVAGADISMLDACKTAGDAKALSQQGHVVFNELEALKIPVVAAIHGACLGGGLELALACHQRVCSDDGKTMLGVPEVQLGLLPGGGGTQRLPRLVGITTALDMMLTGKQIRPKQALKMGLVNDVVPQTILLQTAVEMALAGKRAPKPIKKSLVNQVLEGTSFGRNIIFDQATKQVEKKTQGNYPAPAKIIDCVRQGIAKGMQKGLEVEASHFAELVVSKESEALRSIFFATTEMKKETGAEGATPRKVKKAVILGGGLMGGGIASVTTTKAKIPVRVKDISEKGLSNALAYAYKLLDKGVKRRHMTPAVRDNLMALMTTTTEYKGVKDADIVVEAVFEDLALKHQMVKDIERECGEHTIFASNTSSLPISQIAEAATRPENVIGLHYFSPVEKMPLVEVIAHAKTSPETIATTVAFARKQGKTPIVVQDGAGFYVNRILALYMNEAAQLLLEGQSVEHLDKALVKFGFPVGPITLLDEVGIDVGAKISPILDKELGERFKAPAAFDKLLGDDRKGRKNGKGFYQYGASSKKTKAVDETVYGVLGIKPSTNKDAKALAERCVVQMLNEAVRCLDEGIIASPRDGDIGAIFGIGFPPFLGGPFHYIDTLGAANLVKILEGYQSQFGNRFEPCERLKTMARENVSFF
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_ASHGO
Sequence: MGVPSFFRWLSRKYPKIISPVIEDTPQVVDGVKLPIDYSAANPNGELDNLYLDMNGIVHPCSHPENKPAPETEDEMLLAVFEYTNRVLNMARPRKVLMIAVDGVAPRAKMNQQRSRRFRSARDAKLANEEKARVLAEREAYGEMIDDAVKAKKSWDTNAITPGTPFMDKLAAALRYWTSFKLATDPGWKNLQVIISDATVPGEGEHKIMNFIRSQRADVQYNPNTTHCIYGLDADLIFLGLATHEPHFKILREDVFAQDNRRRPRQHDMMDMSAEEKQALIEQDAEKPFLWLHVSVLREYLSAELLVPRLPFHFDLERAIDDWVFMCFFCGNDFLPHLPSLDVRENSIDILVDIWKAVLPSLKTYLTCDGKLNLKGVEKVLAQLGNRESDIFKKKYEQELRKKEAQERRKMLKNNPNVTKGKVDRNFTVPLESMPVFDVNGNAAAGSLNLTNKDFANMRKEITLANEGNTKALDALKRRSDENRTQRTSDTRDFSQEELESAIEVSKGDNLSAAASLRERILAKRKAAEDPEGAPEPKNPHKAPSASETEAATPASSETASQVDIPISTGMLTPGFLDTDTGVRLFEPGYHDRYYQAKFHVPTGSIDALRKKVVRSYVEGISWVLLYYYQGCPSWTWYYPYHYAPFASDFTGISDLSVTFDLGEPFLPYEQLMSVLPAASSHNLPDVFRSLMSDPESEIYDFYPEEFPIDMNGEKMAWKALVLLPFIDETRLLAAVRQKYPLLSEAERARNVRRDEVLLISNKNTHYERFLARLYTDPAPQPVNFRHFKSGLAGTALSDAEGFRPNTKMLCPLAAGSLPDISTNLFLKTAYRMPQLPAPSKSILLNGFIPPEAQLSPADRDAIMYKYPQRWNPHTMKHNLVPVGPAAVTQYQPRIGGYRAFLFHQQLMQDRPYPPAHMHSHSSGGPPLAQGPRVTQSRYQPRRFH
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  Required for the processing of nuclear mRNA and rRNA precursors.  May promote termination of transcription by RNA polymerase II (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPO2C_HALS3
Sequence: MSTEREAKVYVNGSLVGTHENPEELAEQIREARRRGEVSEMVNVSVRDRTGEVIVNADAGRARRPLLVVENGEPVVTQEEVEAVKNGDIDFEDLVEAGKVEFIDAEEEEDILVGVEEEELTTDHTHLEIDPQLIFGIGAGMIPYPEHNASPRITMGAGMMKQSLGLPAANYRIRPDTRQHLLHYPQKAMVNTQTTEQIGYDDRPAGQNFVVAVMSYEGFNIEDALVMNKGSVERALSRSHFFRTYEGEERRYPGGQEDRFEIPGDDVRGARGEDAYTHLDDDGLVNPETKVDDSSVLLGKTSPPRFLEEPEDMGGLSPQKRRETSVTMRSGEDGVVDTVTLMEGEDGSKLAKVSVRDERIPELGDKFASRHGQKGVVGHLAPQEDMPFTQEGVVPDLVLNPHALPSRMTVGHVLEMLGGKAGSLDGRSVDGTPFTGEGEDEIRGTLEDRGFKSSGKEVMYSGVSGEKIEAEIFVGTIFYHKLYHMVSNKLHARSKGPVQVLTRQPTEGRAREGGLRVGEMERDTVIGHGAAMVLKERLLDSSDREEIHVCGNCGMTAVENYEQRRVYCPNCEEETDVHSIEMSYAFKLLLDEMKALGIAPRLELEEAV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  The Rpo2 subunit (Rpo2N and Rpo2C in this organism) is implicated in DNA promoter recognition and in nucleotide binding.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo2C, DNA-directed RNA polymerase subunit B'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_AERHH
Sequence: MPNEFELAVAALQRDGVIAYATEAVFGLGCDPDSESAVHRLLAIKQRPVEKGLILIAADLAQLQDYIDLDQLTSEQLARVEASWPGPFTWIMPARSNTPAWLTGQFTTLAVRVTAHPQVQALCRAFGKPLVSTSANLTGEEPARRVADIGELLASQLAYILPGEVGGQANPSEIKDARTGAIIRPS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.