PharMolix/UniProtQA huggingface dataset:
Protein: ARAA_GRAFK
Sequence: MTNFENKEVWFITGSQHLYGEETLRQVANNSKEIVEGLNGSDNVPVKLIHQDTVKSSDEITKVMLDANNSSSCIGVILWMHTFSPAKMWIKGLSIIKKPICHFHTQFNAEIPWSKIDMDFMNLNQSAHGDREFGFIMSRMRKKRKVIVGHWKTEVTQKKVGNWQRVALGWDELQHIKVARIGDNMRQVAVTEGDKVAAQIKFGVEVNAYDSSDVTQHIDKVSDDEVNSLLKKYEKDYDLTDALKDGGDQRQSLVDAAKIELGLRAFLEEGGFMAFTDTFENLGALKQLPGLAVQRLMADGYGFGAEGDWKTAALLRAMKVMAQGMEGGTSFMEDYTNHFTEGKDYVLGSHMLEICPSIADSKPTCEVHPLGIGGKEDPVRLVFNSPKGKALNASLVDMGTRFRLIVNEVEAVEPEADLPNLPVARVLWDPKPDMDTAVTAWILAGGAHHTVYTQALSTEFLEDFADIAGIELLVIDDNTSVRQFKDTLNANEAYYHLFQHGM
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: CCA_MARN8
Sequence: MQTYLVGGAVRDKLLGLGVKDRDWVVVGATPEDMIQRGFKQVGADFPVFLHPDTGEEYALARTERKQGRGYHGFSVYSAPDVSLEDDLRRRDLTINAMAETENGDLVDPFNGHADLEQKKLRHVSEAFAEDPLRILRTARFAARLQPLGFSICRETMALMRQMVTSGELGDLVPERVWQEVQRALHEQAPGVFFDVLRELGALQVLIPELTDEQPFRQGLSALQCIHRKQGSTAQHYAALLSGVPEPDAVARAKAMKSPNDCRELTHLVGLFMAQLNGASPETRLTPELAMELLDKADFWRRPDRFGVLLGTLACTLQSEPDHLIQQLELAAHRAQSVTPHPFLQKGIQGKALGEAIRKERVARITEALHLPE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: TMIE_MOUSE
Sequence: MAGRQHGSGRLWALGGAALGACLAGVATQLVEPSTAPPKPKPPPLTKETVVFWDMRLWHVVGIFSLFVLSIIITLCCVFNCRVPRTRKEIEARYLQRKAAKMYTDKLETVPPLNELTEIPGEDKKKKKKDSVDTVAIKVEEDEKNEAKKKGEK
What is the function of this protein?
Unknown.  The protein may play some role in a cellular membrane location.  May reside within an internal membrane compartment and function in pathways such as those involved in protein and/or vesicle trafficking.  Alternatively, the mature protein may be localized in the plasma membrane and serve as a site of interaction for other molecules through its highly charged C-terminal domain.
What are the official names of this protein?
Transmembrane inner ear expressed protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PRLR_ORENI
Sequence: MMTKVGEVLLLLLLPAFVPHTDGTHYSLPGKPTEIKCRSPEKETFTCWWKPGSDGGLPTTYALYYRKEGSDVVHECPDYHTAGKNSCFFNKNNTLIWVSYNITVVATNALGKTYSDPQDIDVVYIVQPHPPEKLEVTVMKDQGWPFLRVSWEPPRKADTRSGWITLIYELRVKLEDEESEWENHAAGQQKMFNIFSLRSGGTYLIQVRCKPDHGFWSEWSSTSYVKVPEYLHREKSVWILVLVFSAFILLLLTWLIHMNSHSLKHCMLPPVPGPKIKGFDKQLLKSGKSDEVFSALVVSDFPPTTSNYEDLLVEYLEVYMPEQQELMVDKGKDHDGCLKSIGSASDSDSGRGSCDSDNLLMDKSGAPKEEQQQQNQEGDQIGKETQGPKEAWEKEAMPCANEDVVSPDASSEKVKTWPSVFSPVTPYSPLDPHNSLEMHKQHCLSNTQFPPGSPSSDHYIKEALQSSYWEVCFNNNQPYPQTEVHPQLQAHSDRNISAVNDRNAPTGLLLPTRMTEYVEVQRVNEENKVLLHPIPSGHSREKACPWVGQRDDYSKVKGVDSDNGLLLQREVVEEESMEMAGAAESCYTSSIAFTTPKQTACSPVALPVQDERVLAVSGYVDTATVFSVHT
What is the function of this protein?
This is a receptor for the anterior pituitary hormone prolactin.
What are the official names of this protein?
Prolactin receptor, PRL-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y795_PYRHO
Sequence: MITDEEIRKVIAPLLLSGAKMLDKHCPKCGSPLFEKDGRVFCPVCEYREKQKKEMVKGVEERLMEKLTQLANSLPDDIDELEKHLRVMEKIIEVLEKYKKLEGRR
What are the official names of this protein?
UPF0148 protein PH0795.
What is the protein family that this protein belongs to?
Belongs to the UPF0148 family.
Protein: RS6_SHIFL
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ATPL_ECO45
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSA_SALPC
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLCEAAQEVGIPLVVNHVGGMFGIFFTDAETVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSEEDINNTIDAARRVFAKQ
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_DESVV
Sequence: MKRTYQPSKIRRKRSLGFRARMATAAGREIIRRRRAKGRKKLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DDX31_MOUSE
Sequence: MKRQAEATKRKHQVSSDAPPAKRRSEISSVLAKKASDKETQRTFKGSTHKTFPPKKYLDSIGNGRQEEKPCIKTSSLFKNNPEIPELHSTVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCVPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNLHFNRIRWLIVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLVDISLHNPVSISVLDKNCNQPNPKEVASIQLNSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKNQKMIVFFSSCELVEFHYSLFLHTLLCHSGTPTSEHLPSASWPLKFLRLHGNMEQEERTSVFHEFSHSETGVLLCTDVASRGLDLPQVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVGEIKMEDILAVLAKDDCFKRRQRGAQKSRASGPQEIRERATVLQTVFEDYVHSSQRMVSWAKKALQSFIRAYATYPKELKSIFHVRALHLGHVAKSFGLRDAPRNLSVSAVKKASLKRPHPRRKTQRKQHLVPAEVLHSEHSSGLEGGATKCRKQGKQQGLQVAPSKPGPWRE
What is the function of this protein?
Probable ATP-dependent RNA helicase (By similarity).  Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX31, DEAD box protein 31.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Colocalized with NPM1 in the nucleoli.
Protein: RL33_GLAP5
Sequence: MAAKGNREKIKLVSTAETGHFYTTTKNKRNMPEKMEIKKFDPVVRKHVVYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: COL_PIG
Sequence: MEKVLALLLVTLTVAYAVPDPRGIIINLDEGELCLNSAQCKSNCCQHDTILSLSRCALKARENSECSAFTLYGVYYKCPCERGLTCEGDKSLVGSITNTNFGICHDVGRSSD
What is the function of this protein?
Enterostatin has a biological activity as a satiety signal.
What are the official names of this protein?
Colipase, Procolipase II.
What is the protein family that this protein belongs to?
Belongs to the colipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATN1_RAT
Sequence: MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEETSTPKANKQGRSEEISESESEETSAPKKTKTEELPRPQSPSDLDSLDGRSINDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPPPPDSIPRQPESGFEPHPSVPPTGYHAPMEPPTSRLFQGPPPGAPPPHPQLYPGSAGGGVLSGPPMGPKGGAAASSVGPPSGGKQHPPPTTPIPISSSGASGAPPAKPPNTPVGAGNLPSAPPPATFPHVTPNLPPPPALRPLNNASASPPGMGAQPIPGHLPSPHAMGQGMSGLPPGPEKGPTLAPSPHPLPPASSSAPGPPMRYPYSSCSSSSVAASSSSSAATSQYPASQTLPSYPHSFPPPTSMSVSNQPPKYTQPSLPSQAVWSQGPPPPPPPYGRLLPNNNTHPGPFPPTGGQSTAHPPAPAHHHHQQQQQPQPQPQPQQHHHGNSGPPPPGAYPHPLESSNSHHAHPYNMSPSLGSLRPYPPGPAHLPPSHGQVSYSQAGPNGPPVSSSSNSSGSSSQAAYSCSHPSSSQGPQGASYPFPPVPPITTSSATLSTVIATVASSPAGYKTASPPGPPQYSKRAPSPGSYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSSLSSLPPPPAAPTTGPPLTATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL
What is the function of this protein?
Transcriptional corepressor.  Recruits NR2E1 to repress transcription.  Promotes vascular smooth cell (VSMC) migration and orientation.  Corepressor of MTG8 transcriptional repression.  Has some intrinsic repression activity (By similarity).
What are the official names of this protein?
Atrophin-1, Dentatorubral-pallidoluysian atrophy protein homolog.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cell junction. Note=Shuttles between nucleus and cytoplasm. Colocalizes with MTG8 in discrete nuclear dots (By similarity). Colocalizes with FAT1 in the perinuclear area, at cell- cell junctions and leading edges of cells.
Protein: MLXPL_MOUSE
Sequence: MARALADLSVNLQVPRVVPSPDSDSDTDLEDPSPRRSAGGLHRSQVIHSGHFMVSSPHSDSLTRRRDQEGPVGLADFGPRSIDPTLTHLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVQRRKSPVCGFVTPLQGSEADEHRKPEAVILEGNYWKRRIEVVMREYHKWRIYYKKRLRKSSREGDFLAPKQVEGGWPPPERWCEQLFSSVVPVLLGGSEEEPGGRQLLDLDCFLSDISDTLFTMTQPSPSSLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMEISDFFTNYRPPQTPTSSNYIESPSFGPMADSLFSSGILAPEMPSPASSSSSSGMTPHSGNTRLQARNSCSGPLDPNPFLSSEFLLPEDPKTKIPPAPGPTPLLPFPTPVKVHGLEPCTPSPFPTMAPPPSLLPEESLLSARFPFTSAPPAPGVSTLPAPTTFVPTPQPGPGPVPFSVDHLPHGYLEPVFGPHFTVPQGMQPRCKPSSPSPGGQKASPPTLASATASPTATATARDNNPCLTQLLRAAKPEQALEPPTMPGTLLRPPESPQDTVSEIPRARAFFPPIPAPTPPRPPPGPATLAPPRSLVVPKAERLSPPASSGSERRLSGDLNSIQPSGALSVHLSPPQTVLSRGRVDNNKMENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAAMQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASLHSLRQTSLAWLEQYCSLPALRPTVLNSLRQLSTSTSILTDPSLVPEQATRAVTEGTLGRPL
What is the function of this protein?
Transcriptional repressor.  Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
What are the official names of this protein?
Carbohydrate-responsive element-binding protein, ChREBP, MLX interactor, MLX-interacting protein-like, Williams-Beuren syndrome chromosomal region 14 protein homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: YKPA_BACSU
Sequence: MIAVNNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKVLSGEIEPQTGDVHMSPGERLAVLKQNHFEYEEYEVLKVVIMGHKRLYEVMQEKDAIYMKPDFSDEDGIRAAELEGEFAELNGWEAESEAAILLKGLGISEDLHTKKMADLGGSEKVKVLLAQALFGKPDVLLLDEPTNHLDLQAIQWLEEFLINFENTVIVVSHDRHFLNKVCTHIADLDFNKIQIYVGNYDFWYESSQLALKLSQEANKKKEEQIKQLQEFVARFSANASKSKQATSRKKLLEKITLDDIKPSSRRYPYVNFTPEREIGNDVLRVEGLTKTIDGVKVLDNVSFIMNREDKIAFTGRNELAVTTLFKIISGEMEADSGTFKWGVTTSQAYFPKDNSEYFEGSDLNLVDWLRQYSPHDQSESFLRGFLGRMLFSGEEVHKKANVLSGGEKVRCMLSKAMLSGANILILDEPTNHLDLESITALNNGLISFKGAMLFTSHDHQFVQTIANRIIEITPNGIVDKQMSYDEFLENADVQKKLTELYAE
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YkpA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: MNMA_ECO24
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_CYTH3
Sequence: MFPKLSESFYLRENVQLISKELLGKVLVTYIDGKYTAGIITETEAYQAPEDKASHAFNNRRTTRTEVFYNKGGIGYVYLCYGIHHLFNVVTNNENIPHAILIRSVEPLEGVDIMMQRRNKKKLDKTLTAGPGALSQALGITRLHNKIPLSANTVWIEDRNIPVESIVSTTRVGIDYAQEYKDKPWRYYIAGNKWISRG
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: AF9_ASHGO
Sequence: MAPAQAKRIKTLSVARPIVYGNTAKKMGDVRPAIAPSEHTHMWTIFVRGPQGEDISYFIKKVVFKLHETYPNPVRVVDAPPFELTETGWGEFEINVKVHFVDEANEKMLNFYHHLRLHPYTEEDGRRSDGDEVSSVFYDEIVFNEPNEAFFAKMIEQPGNLLPSNKTPDCVFSLQLEQEEIDRIQQGIGKVDEEIEQLKQKLEQDLAK
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity).
What are the official names of this protein?
Protein AF-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAF9 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMG_PROMA
Sequence: MSNYSNAKEKFDVIVVGGGHAGCEAAIATAKLGLSTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGVIGRLADSTALQKRILNASRGPAVWALRAQTDKRQYSIEMLQMLQETPNLSLREAMVTDLEIKSSPNRKKIKEQSEEKTIGQVQGIKTYFGSIYLAKAVILTTGTFLKGKIWIGNQSMDAGRAGEQAATGLTEALQKLGFETSRLKTGTPPRVDRRTIDLGSLEEQKSDAADRFFSFDPERWKSGQQMSCYMTRTTQKTHQLIKNNLHLTPIYGGFINSKGPRYCPSIEDKIVRFSDKESHQIFLEPEGRNTPEIYIQGLSTGLPEGMQLQLLRTLPGLKNCVMLRPAYAVEYDYLPATQLLASLETKKIEGLFSAGQLNGTTGYEEAAAQGLVAGLNAARYVNNQDAIIFPREESYIGTMIDDLIKKDLREPYRVLTSRSEYRLILRGDNADRRLTPLGYKVGLVNDYQWNIFQIKQSNMEKEKKRLEQQRIKDSDPIALKIEKESGASIKGSITLANLLRRPGMHMNNLIRHKLANNSLPLDVREGVEIDIKYSGYLKRQNLQIEQIKKQNKRALPSEVNYTNIKTLSQEAREKLNATQPKTFGEASQLPGVSKADLSALLIWLKIQNRKSHAAKIRNNEAKIKLHSNLGVDF
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_YERPY
Sequence: MAKNIQAIRGMNDYLPADTAIWQRIESILKQVLSGYGYSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQLGAEVFGLPGPDIDAELILLTARWWRALGIFEHVKLELNSIGSLAARADYREALVAFLEQHVEVLDEDCKRRMYSNPLRVLDSKNPDVQQLLDDAPKLSDYLDEESKQHFAGLCELLDKASIPYTVNERLVRGLDYYNRTVFEWVTHSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNADFQVPATVDAYVISSGEGAQSAAMLLAESLRDALPTLKIMTNYGGGNVKKQFTRADKWGARVALMLGESEVAAQQVVVKDLRNGEQETLAQADVAARLALMLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_LISMO
Sequence: MLRLGSHVSMSGKKMLLGASEEAASYGSNTFMIYTGAPQNTRRKPIEELNIEAGLEHMKAHDMADIVVHAPYIINIGNSVKPETFELGVNFLQSEIERTRALGAKQIVLHPGAHVGEGADKGIKQIIQGLNEALIHDQDVQIALETMAGKGSECGRTFEELAQIIDGVTHNELLSVTFDTCHTHDAGYDIVNDFDGVLNQFDKIVGIDRLKVLHINDSKNERGAHKDRHANIGFGHIGFDALHYIVHHPQLADVPKILETPYVGGDKASKKAPYKWEIAMLKNGEFDPDLLNKIQNS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RNR_CHLTR
Sequence: MGKAKNKKKFLKNRKQVLVPGTLFVHSRKGFGFVSPDQPELYPFDIFISASDLKGALDGDHVLVALPFSLRGGEKRKGVIHKVLSRGKTVLVGTIVSLINPTLAMVYVNTIGPEHPLKAELLPKRTYKLGDRLLLKTPVWKENYPSREPPPLAMLEFIGNISNAKTDFPVIKAEFSITEEFPDAVVQEASQFLQKHVTQALHSRKDLRDLLCFTIDSSSAKDFDDAVSLTYDHEGNYILGVHIADVSHYVTPNSALDREAAKRCNSIYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVFMTFSKEGFLSDYRILRSVIRSKYRMTYDEVDEIIEKKQTHPISKTILKMAELSRIFSDIREQRGCTRLVLPSFTMSLDNLQEPVALIENKQTAAHKLIEEFMLKANEVIAYHISHQGITMPFRTHEPPNEESLLVFQETAKAMGFTITQTPAQEPDYQYLLQETTAGHPLEPILHSQFVRSMKTASYSTENKGHYGLCLDYYTHFTSPIRRYVDLIVHRLLFHPLSVEEEHLEQIVRACSSQERIAAKAEGAFVNIKKARFLKKFIEEQPATLYKAFIITASPEGISFVLPEFCHEGFIPAAKLPQAYVLQTKIGLEELPEHLRPGAVISVQLASVTLLTQSIEWTLVEATTKAKAKRTSKKKKTESVTTKEKKKSPAKKKKGATKTKKGSGKN
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_ARTS2
Sequence: MHILDTVDAASLRTDVPQFRAGDTLKVHVNIIEGKNSRVQVFQGFVLGRQGDGIRETFTVRKVSFGVGVERTFPVHSPIIDKIEVVTKGDVRRAKLYYMRALRGKAAKIKEKRDFSTAK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: COG5_SCHPO
Sequence: MEFRYDFSDYKKSDFDPKAQAERVLISVHADSDVNEDKEVARKRLGYALKEVERQITDLIVHEETTLTKNVSSSLNAQSYLQDIEGKLEQLMLVYERIRSLVVIPSENLGPLHEAIVNLHSTYMTLYWLGEFFGIQAKLFPLFQGSINENEKLSRYYQASLLLQESDQLLSRFPLMKRQSSVSLLLKLNITNRSRIIKETSSYLLSQEDQLSFSVNSNGFTNACSVLYMLDKYLLEQDLTRLLSSRIQKAIIQFDSIFQLSPTTRRLLHNSTDPSAANSTIWSKFEDGWYQISKIGAQCVFWERSLQKANICNPDYPNLLEYFQMQPNFILDGATICIYFFKELAISISSKMQMLDRRDPILLRVFRSDFQRVTHIVEQAIARSSSEIVNKDTRECSIVMNSLRVLAPKNP
What is the function of this protein?
Acts as essential component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking.  COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 5, COG complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the COG5 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AAIM1_CAEEL
Sequence: MRLLFFFSILYTASLCCQLKDFLPCVMQLSAQKVDFNMNPIEVIFNITTEAKLMHTCRTYSRILPCFDQKMVQCGKPSEKTQLERGKRLHSYLCAPFSLQRQKIFLRRSKCIQDVLAEPQSSVCNRNDTVFADKLQSCREMCTRPDCVSKIELSEVSTCTYINIGKKCTAEAAQFFAQMQQVLTNKEYPMQCQYDLRKKPESELKKGLPIESLVAQTTSSTTYVTVHPPALPSVIDGVVTRTSLPIMRRTDPNSKFKPRPTTSQSNGPVIKTVIVDERGAPMNQPTSTQKPKVVHKFLPNPYTTKNPNTLKNDIIRTTRTIIPVVDKHTYVPWNYKVDAVQVSTLTSALAPVKPTETVISSPPVAFNFKLPAEQTSTQPFRVEINWHDDEVKQEPTKAPGVFVSPWYLKTPSHIPPEIEFATPTPLISSPLEAVSPILSQLKSNSLNFTELGNQANNYFSAALSAFAETKKEMAHNDPWRTIIDAVAPTIHKFSPDVIPRIREEINRIQPHQQKN
What is the function of this protein?
(Microbial infection) Promotes infection by microsporidian pathogens such as N. parisii in the early larval stages of development (PubMed:34994689).  Involved in ensuring the proper orientation and location of the spore proteins of N. parisii during intestinal cell invasion (PubMed:34994689).
What are the official names of this protein?
Protein aaim-1, Antibacterial and aids invasion by microsporidia 1 protein.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD4_RAT
Sequence: MASKLLRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTNTEVGDVAKQYLEKGLLVPDHVITRLMMSELETRSAQHWLLDGFPRTLVQAEALDRICDVDLVISLNIPFETLKDRLSRRWIHPSSGRVYNLDFNPPQVLGVDDITGEPLVQQEDDKPEALAARLRRYKDAAKPVIELYKSRGVLHQFSGTETNRIWPYVYTLFSNKITPIQSKEAY
What is the function of this protein?
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates (By similarity).  Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor (By similarity).  Also displays broad nucleoside diphosphate kinase activity (By similarity).  Plays a role in controlling cellular ATP levels by regulating phosphorylation and activation of the energy sensor protein kinase AMPK (By similarity).  Plays a protective role in the cellular response to oxidative stress (By similarity).
What are the official names of this protein?
Adenylate kinase 4, mitochondrial, AK 4, Adenylate kinase 3-like, Adenylate kinase isoenzyme 4, GTP:AMP phosphotransferase AK4.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IF6_DICDI
Sequence: MATRLQYENSCDVGVFLKLTNKYCLVGQCGSKQFLHTVENRLADHIPVVETSIAGTRIVGRLSAGNKNGLLLPNTCTDQELQQIRNSLPDDVVVQRIEEKFSALGNCIATNDYVALVHPDIDRETEEIIADVLGVEVFRQTVSGNVLVGTYCALTNQGALVHPMTSIADQDELSSLLQVPLVAGTVNRGNECVAAGCVVNDWTAIVGADTTATEISVIESIFALQGSKPSNIINNIRNSIVDNV
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: AROQ_BRUA1
Sequence: MTKTVFVLNGPNLNLLGKREPGIYGVATLDDIEASCKREAGQLELQIDFRQSNHEGDLVSWIQEAGEKNAYVLINPAAYSHTSVAIHDAIRSARVTVVEVHLSNIHAREAFRHHSHVSAVAKGVICGFGAEGYLLGLRALAAIAKEEEKNGQSIKGA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: KGUA_THEMA
Sequence: MKGQLFVICGPSGAGKTSIIKEVLKRLDNVVFSVSCTTRPKRPHEEDGKDYFFITEEEFLKRVERGEFLEWARVHGHLYGTLRSFVESHINEGKDVVLDIDVQGALSVKKKYSNTVFIYVAPPSYADLRERILKRGTEKEADVLVRLENAKWELMFMDEFDYIVVNENLEDAVEMVVSIVRSERAKVTRNQDKIERFKMEVKGWKKL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.