PharMolix/UniProtQA huggingface dataset:
Protein: RL7_MOUSE
Sequence: MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).  Binds to G-rich structures in 28S rRNA and in mRNAs (By similarity).  Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_AGARV
Sequence: MLDVCLLGTAGMMPLPNRWLTALSLKYNGSNILIDCGEGTQIAMKEAGINFKPIDILCITHFHADHISGLPGLLLTMGNAERTEPLTIIGPKGLTRVVTALRTIAPELPFEIKCIELNEQDEYFEMNGYHIHAFRVKHAVLCYGYSVEIKRSGRFSVERANEKEIPMRLWNPLQKGNTVEFEGRVYTPDMVLGPARKGIKVTYCTDSRPLEHIVEAAEGSDLFICEGMYAEKEKIVKAKQYKHMTFYEAADMAKRAGVKELWLTHFSPSLVRADDYMPQVRDIFANAYLGKDAKSVELMFDED
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: GSA_SHIDS
Sequence: MSKSENLYSAARELIPSGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLHELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BACCN
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRFYVDHLLAPQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANMLAQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSVGEEQLGTIAILGPTRMHYARVITLLQLFTKHFTEGLNGLYKSK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: PROA_SYNJA
Sequence: MSLVTDSPSLPEAAADSPLLAQVQLARAAARCTATLPTAIKNAALEAMATALLEHQEAILAANQADLEQAAEQVKAGELSASAYARLKLDAQKLADAVAGVRQVLRLPDPVGQALLIRELDEGLVLERRTYPLGVLGVIFESRPDALVQIAALAVKTGNSVLLKGGSEGLCSCQALMAAIQAGLQQIPEFPQGSLQLLTSRAEVKALLQLEGLVDLIIPRGSSSFVRYIMENTRIPVLGHADGLCHLYVDRAADVDMAVRLTLDSKTQYPAACNAIETLLVHAEIAPRFLPLAVQALREKGVELRGDPRCRQLVPDLIPATEDDWSTEYADLILSIKVVGSLDEAIAHIERYGSRHTEAIVTEDAAAAQRFLDEVDAAGVFHNASTRFADGFRYGLGAEVGISTQKLPPRGPVGLEGLVTYRYQLRGRGHLVADYTGPQARPFQHRDRLNTTGLS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1004_SYMTH
Sequence: MGRKWENIKRSKAKLDQQRGATFSRITKDIMKAAREGGPDPETNFLLKVAVAAARKANMPNENIQRAIARGAGLDSAERFDEIVYEGYGPGGVAIMMNIVTDNRNRTAADVRHIFSKHGGSLGETGCVSWMFKKRGVIEIDRGETPIGEDDLMMIALDAGAEDLVTEEDSYAIYTAPDALNQVMKQLEAAGVPVEKGEVAMVPTTTVAVSGEEAEQLMRLLDLLEEHDDVQNVYTNADISEA
What are the official names of this protein?
Probable transcriptional regulatory protein STH1004.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y227_ATV
Sequence: MFDVKSIKVPLPPEDPDKILFRIFTSDLLDGESQVDVMTHKTSNAKYPMLVYLNANELVANALRGGPTSAGFALRLITPLFVPDYPLVLVRSILCRGTVCVGVDHKLNVEFLETFIQSDKLLYLVALNYLGYSEDGALFFEDVKTYELDISNEQREVAKQYLEVMKKTTTDKINKAYDVYAKEKRHRAGYGSLLAKMAEKLGTNMESLSLIGVEPFMSSKNEGTSTS
What are the official names of this protein?
Uncharacterized protein ORF227.
Protein: ENTS_ECOLC
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRHFRQTPPQVTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSN1_MICMU
Sequence: MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNREQQDHGDRRRLGNPEPLSNGRPQGNSGPVVERDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSVLNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNTKYNAQGTEREAQASVPENDDGGFSEEWEAQRDSQLGPHRSTSVSRAAVQEISSSIPASEDPEERGVKLGLGDFVFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
What is the function of this protein?
Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  Requires the presence of the other members of the gamma-secretase complex for protease activity.  Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.  Stimulates cell-cell adhesion via its interaction with CDH1; this stabilizes the complexes between CDH1 (E-cadherin) and its interaction partners CTNNB1 (beta-catenin), CTNND1 and JUP (gamma-catenin).  Under conditions of apoptosis or calcium influx, cleaves CDH1.  This promotes the disassembly of the complexes between CDH1 and CTNND1, JUP and CTNNB1, increases the pool of cytoplasmic CTNNB1, and thereby negatively regulates Wnt signaling (By similarity).  Required for normal embryonic brain and skeleton development, and for normal angiogenesis (By similarity).  Mediates the proteolytic cleavage of EphB2/CTF1 into EphB2/CTF2 (By similarity).  The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is therefore involved in calcium homeostasis.  Involved in the regulation of neurite outgrowth (By similarity).  Is a regulator of presynaptic facilitation, spike transmission and synaptic vesicles replenishment in a process that depends on gamma-secretase activity.  It acts through the control of SYT7 presynaptic expression (By similarity).
What are the official names of this protein?
Presenilin-1, PS-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic granule. Cell membrane; Multi-pass membrane protein. Cell projection, growth cone. Early endosome. Early endosome membrane; Multi-pass membrane protein. Cell projection, neuron projection. Cell projection, axon. Synapse. Note=Translocates with bound NOTCH1 from the endoplasmic reticulum and/or Golgi to the cell surface. Colocalizes with CDH1/2 at sites of cell-cell contact. Colocalizes with CTNNB1 in the endoplasmic reticulum and the proximity of the plasma membrane. Also present in azurophil granules of neutrophils. Colocalizes with UBQLN1 in the cell membrane and in cytoplasmic juxtanuclear structures called aggresomes.
Protein: SODC2_SOLLC
Sequence: MVKAVAVLNSSEGVSGTILFTQDGAAPTTVNGNISGLKPGLHGFHVHALGDTTNGCMSTGPHYNPAGKEHGAPEDEVRHAGDLGNITVGEDGTASFTITDKQIPLTGPQSIIGRAVVVHADPDDLGKGGHELSKSTGNAGGRIACGIIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn] 2.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_DELAS
Sequence: MNIDQYLPVLLFILVGMGVGVVPLVLGYVLGPNRPDAAKNSPYECGFEAFEDARMKFDVRYYLVAILFILFDLEIAFLLPWAVALRDVGGAGFAAVLIFLTVLVVGFVYEWKKGALDWD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: E311_ADE05
Sequence: MTNTTNAAAATGLTSTTNTPQVSAFVNNWDNLGMWWFSIALMFVCLIIMWLICCLKRKRARPPIYSPIIVLHPNNDGIHRLDGLKHMFFSLTV
What are the official names of this protein?
Early E3A 10.5 kDa glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3A-1 family.
What are the subcellular locations of this protein?
Host nucleus membrane; Single-pass membrane protein.
Protein: PLSY_BURO1
Sequence: MQILLAALVAYLIGSVSFAVVVSSVMGLADPRSYGSKNPGATNVLRSGNKKAAILTLVGDAFKGWIAVWLARHFGLPDVAIAWVAIAVFLGHLYPVFFRFQGGKGVATAAGVLLAVHPVLGLATALTWLIVAFFFRYSSLAALVAAVFAPVFDVFLFGMPGHNPIAWAVLAMSVLLVWRHRGNISKLLAGQESRIGDKKKAAADGGAQDGGKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
Protein: RNPA_BARQU
Sequence: MHFMKRKHPCRIRKRADFLAVRTGEKRRGPLFLLEVKSREQTAGIKSPLVARVGFTVTRKNGNAVKRNRIKRRLREAVRVGLTDDIEAGTDYVIVAHSDALHAPFTFLISELSRRIKPKTKHQKRQQGNMNGI
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ALR_PERPY
Sequence: MTLQNFYRDTWAEINLDAIFENAANMKKHLPPEITLFAVVKANAYGHGDVEVAETAIQAGAGYLAVAFLDEALALRKKGITAPILVLGASRPEDAQIAARESITLTVFQAGWLEAAQSFLEGTVLTIHLKCDSGMGRIGIRKQEEMNEIERFLQKTKCFVLEGIFTHFATADQLDTEYFSKQLARFEEMLTWLKEKPKYVHAANSAALLRFPNAVFNSVRMGISLYGLSPSMEMKEVLPFALRPAFSLKTKLVHVKNISKGQSVSYGATYTAEEDTWIGTLPIGYADGWIRMLQGQEVLLEGGRSPLVGRICMDQCMVKLSREFPVGTEVTLIGKNGTECITVDDIAEKLNTINYEVTCMISSRVPRMYLKDGRITGVVNQLI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  Does not act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PP1B_PIG
Sequence: MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Involved in regulation of ionic conductances and long-term synaptic plasticity.  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation.  May dephosphorylate CSNK1D and CSNK1E (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.
Protein: XPT_PSEAE
Sequence: MDILKDKIRSEGIVLSEHVLKVDAFLNHQIDPQLMQQVGHAFATRFRDQGITKIVTIEASGIAPAVMAGLELGVPVIFARKYQSLTLKDNLYISKVFSFTKQTESTIAISAKHLNAHDHVLVIDDFLANGHAAKALIDLIGQAGASIAGLGIVIEKSFQDGRALLESEGYRVESLARVKSLAGGQVEFLD
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VME1_CVCAI
Sequence: MKKILFLLACAIACVYGERYCAMTESSTSCRNSTAGNCASCFETGDLIWHLANWNFSWSVILIIFITVLQYGRPQFSWFVCGIKMLIMWLLWPIVLALTIFNAYLEYRVSRYVMFGFSVAGATVTFILWIMYFVRSIQLYRRTKSWWSFNPETSAILCVSALGRSYVLPLEGVPTGVTLTLLSGNLCAEGFKIAGGMNIDNLPKYVMVALPVRTIVYTLVGKKLKASSATGWAYYVKSKAGDYSTDARTDNLSEHEKLLHMV
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: CILP2_HUMAN
Sequence: MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEAAQAQARASGPLRTRRGRVRQ
What is the function of this protein?
May play a role in cartilage scaffolding.
What are the official names of this protein?
Cartilage intermediate layer protein 2, CILP-2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: B2_HHV6Z
Sequence: MQPMTKKKHTTASKRSPARPPSLSPPLESRRRVGGKSPERLHGNAPPTPPRSPLPPSPSPEHTRRLSPQRRRPQRQRKL
What are the official names of this protein?
Protein B2.
Protein: PEPQ_ECO45
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: 3LKB_BUNMU
Sequence: MKTLLLTLVVVTIVCLDLGYTRTCLISPSSTPQTCPNGQDICFLKAQCDKFCSIRGPVIEQGCVATCPQFRSNYRSLLCCTTDNCNH
What is the function of this protein?
Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors (nAChR) with high affinity (IC(50)<100 nM).  Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs.
What are the official names of this protein?
Kappa-bungarotoxin, Kappa-bgt, Kappa-1-bungarotoxin, Long neurotoxin 2, Neuronal bungarotoxin, nBgt, Toxin F.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Kappa-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PEPE_ECO81
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEVGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN6_DICDI
Sequence: MTDTTTTTTTDANKLVLEKSANSSGLEVDLHPLVLINISDHFTRTKVQSNYQDNCRVIGVILGVQNGRNVEICNSFEMVYATVDKQLVLDIEYLRKKYEQLFPLYDLLGWYSTGSQVSKDDILLHKQISEHNESPLYLMLDTDSPKSKDLPVIIYESELHIVNDEPTTIFVKTPYKIQTGEAERIGVNHIAKVTPSGSEGSGLTSHLFTMHNAISMLNIRVKALSDYLQAVKEKRLPYEQNILRKASSLCNQLPTIDTHDFKKSYLQEYNDVLLVTYLASITKTSASLNDTIDKYLVSNEKQSKRRFYQ
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity.
What are the official names of this protein?
COP9 signalosome complex subunit 6, Signalosome subunit 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic vesicle, phagosome.
Protein: IRAD_ECOL5
Sequence: MMRQSVQTVLPESTGNNTLSLRDSVCRDLFQLFSSPHSPLPILLVSGMPEWQGHNQSDKLLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCYELAISLEMMLYHDDEPLTFDLVWQKGSWHRTMPQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_PARMW
Sequence: MEIRRRPPNPKVRVAHLEYAVPHDEEEPKNILEKIVWAKDREVDAARERVPLQTLKRQIEDLPPTRDFLAALREAPVQPAVIAEVKKASPSKGVIREDFDPVAIAEAYAAGGARCLSVLTDKTFFQGGFDVLVEVRQAVDLPLLCKEFVLSPYQLFQARAAGADAVLLIAAILTDQDLQYLKKAAAALGLDVLVEVHDAAELERVLNLGGFPLIGINNRDLTSFETDLSTTEQLMERFGDRLQDQGSLLVSESGLFDRSDLDRVKAAGADAVLVGEALMRQQDVQSALTNLIHG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ARFI_ORYSJ
Sequence: MAAAMEMAANPGGSGTCSDALFRELWHACAGPLVTVPKRGERVYYFPQGHMEQLEASTNQQLDQYLPMFNLPSKILCSVVNVELRAEADSDEVYAQIMLQPEADQSELTSLDPELQDLEKCTAHSFCKTLTASDTSTHGGFSVLRRHAEECLPQLDMSQNPPCQELVAKDLHGTEWHFRHIFRGQPRRHLLTTGWSVFVSSKRLVAGDAFIFLRGESGELRVGVRRLMRQVNNMPSSVISSHSMHLGVLATASHAISTGTLFSVFYKPRTSRSEFVVSVNKYLEAKKQNLSVGMRFKMRFEGDEAPERRFSGTIIGIGSVPAMSKSPWADSDWKSLKVQWDEPSAIVRPDRVSPWELEPLDASNPQPPQPPLRNKRARPPASPSVVAELPPSFGLWKPPSEAAQTLSFSEPQRAREIFPSIPASIFSASSHVEFNSKNEPSILSNQFYWSMRDSKTDSFSASTNKTRVERKQEPTTMGCRLFGIEISSAVEEALPAATVSGVGYDQTVLSVDVDSDQISQPSNGNKSDAPGTSSERSPLESQSRQVRSCTKVIMQGMAVGRAVDLTKLNGYGDLRSKLEEMFDIQGDLCPTLKRWQVVYTDDEDDMMLVGDDPWDEFCSMVKRIYIYSYEEAKLLAPKSKLPVIGDTIKLSSMNSSHESVDLDNHASVTNRDC
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
What are the official names of this protein?
Auxin response factor 9.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.