PharMolix/UniProtQA huggingface dataset:
Protein: MTND_HAHCH
Sequence: MSSLRIYNDNDFSQPLVFTEDGAEISRQLNEAGIRFERWSTRELDEGATPDSILAAYQEEVEKLKAENGFTTADVVSLTPAHPQKDEFRKKFLDEHRHSEDEVRFFVRGQGLFYLHLEDKVYVVLCRKNDLISVPNGTKHWFDMGPEPEFTCVRLFTNPEGWVAQFTGDEIASKAPRFEQLIEEA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: YO309_YEAST
Sequence: MQMLIPQRLLLILNPILMMKRKKRKKRKKRRERETMMKIPRILKKLRRKRRTRRKRRKRRKRRRRKRRKRRRKRSPRKRRKRRNKDAFYILIISDPSRSLLFGFRKFSIIIQCLTYFSFHILFHNL
What are the official names of this protein?
Putative uncharacterized protein YOR309C.
Protein: HPN_HELPJ
Sequence: MAHHEEQHGGHHHHHHHTHHHHYHGGEHHHHHHSSHHEEGCCSTSDSHHQEEGCCHGHHE
What is the function of this protein?
Strongly binds nickel and zinc.  Binds other metals less strongly: cobalt > copper > cadmium > manganese.  May act to increase, or at least to preserve, urease activity.  Exact function is still unknown (By similarity).
What are the official names of this protein?
Histidine-rich metal-binding polypeptide.
Protein: DXR_XANC8
Sequence: MSGSSLRRVAVFGATGSIGASALDVIARHPERLRASVLSAGSKVDALLALCVLHRPAHAVIADAALYPALRDGLRAAGLTTQAHAGDQALDALAASDACDTVVAAIVGAAGLSSTLAAAAAGKRLLLANKESLVLAGELLTRTAAAAGAEIIPIDSEHSAIFQCLRSCDASRGVRRVILTASGGPFRGRQRAQLAEVTPAQAVAHPKWSMGPKISVDSATLMNKGLEVIEAHHLFGLPGEQIDVLVHPQSLVHSLVEFVDGSTLAQLGLPDMRTTLAVGLAWPERVESGVGGLDLLQQGRLDFEAPDTEAFPCLRLAWDALRAGGTAPAILNAANEVAVSAFLQGKVGFLAIPALVEHTLTTLQRQNADTLNALLFADAEARRTTERALAHHSLHA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: DUS_STAAC
Sequence: MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: PVAA_STRP8
Sequence: MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAENDTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLALAEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYFYYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF
What are the official names of this protein?
Pneumococcal vaccine antigen A homolog.
What are the subcellular locations of this protein?
Cell surface.
Protein: YTFE_SALA4
Sequence: MAYRDQPLGELALSIPRASALFRQYDMDYCCGGKQTLARAAARHDVDIDIIEAQLAQLAEQPIEKDWRAVPLADIIDHIVVRYHDRHREQLPELILQATKVERVHADKPNVPRGLTKYLTALHEELSSHMMKEEQILFPMIKQGMGRQATGPISVMESEHDEAGELVDVIKHVTQNVTPPPEACTTWKAMYNGINEMIDDLMEHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_BRUA2
Sequence: MSSSSDAIKAALEKGRAAGLSATGGKNADYIPFLASVPSDLFGLAVVTADGQTFKTGDADIAFAIESISKVFTLALVMEEIGPDSVREKVGADPTGLPFNSVIALELHNGKSLSPLVNAGAIATASLVPGDTADARWNNILECQCGFAGRRLKLSNEVNQSEQTTNFHNRAIAWLLYSAGTCYSDPMEAVDIYTRQCSTLVTATDLATMGATLAAGGVNPISGKRMVSAGNVAPILVEMTMEGLYTALGDWAYTVGLPGKSGVGGGIMAVVPGELAIAAFSPPLDPAGNSVKAMAAVAAVADSLGHNLYTTRGKVSS
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: DEAH5_ARATH
Sequence: MEKEELNKLNHLSLVSNVCNELETHLGSAEKVLAEFIIDLGRHSETVDEFDKNLKEAGAEMPDYFVRSLLTTIHGIYPPKPKSEKKKEEGDDQKFKGLAIKDTKDKVKELEKEIEREAEERRREEDRNRDRDRRESGRDRDRDRNRDRDDRRDRHRDRERNRGDEEGEDRRSDRRHRERGRGDGGEGEDRRRDRRAKDEYVEEDKGGANEPELYQVYKGRVTRVMDAGCFVQFDKFRGKEGLVHVSQMATRRVDKAKEFVKRDMEVYVKVISISSDKYSLSMRDVDQNTGRDLIPLRKPSDEDDSSRSNPSYRTKDGQVTKTGISGIRIVEENDVAPSRRPLKKMSSPERWEAKQLIASGVLRVDEFPMYDEDGDGMLYQEEGAEEELEIEMNEDEPAFLQGQTRYSVDMSPVKIFKNPEGSLSRAAALQSALTKERREMREQQQRTMLDSIPKDLNRPWEDPMPETGERHLAQELRGVGLSAYDMPEWKKDAFGKTPTFGQRSKLSIQEQRESLPIYKLKKELIQAVHDNQVLVVIGETGSGKTTQVTQYLAEAGYTTKGKIGCTQPRRVAAMSVAKRVAEEFGCRLGEEVGYAIRFEDCTGPDTVIKYMTDGMLLREILIDENLSQYSVIMLDEAHERTIHTDVLFGLLKKLMKRRLDLRLIVTSATLDAEKFSGYFFNCNIFTIPGRTFPVEILYTKQPETDYLDAALITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVPELIILPVYSALPSEMQSRIFDPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVYNPKQGLESLVITPISQASAKQRAGRAGRTGPGKCYRLYTESAYRNEMPPTSIPEIQRINLGMTTLTMKAMGINDLLSFDFMDPPQPQALISAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGCSDEILTMIAMIQTGNIFYRPREKQAQADQKRAKFFQPEGDHLTLLAVYEAWKAKNFSGPWCFENFIQSRSLRRAQDVRKQLLSIMDKYKLDVVTAGKNFTKIRKAITAGFFFHGARKDPQEGYRTLVENQPVYIHPSSALFQRQPDWVIYHDLVMTTKEYMREVTVIDPKWLVELAPRFFKVSDPTKMSKRKRQERIEPLYDRYHEPNSWRLSKRRA
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5, DEAH RNA helicase homolog PRP22.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. PRP22 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAA_LACLS
Sequence: MSDTTLEKIIVLDYGSQYNQLIARRIREIGVFSELMSHKVTAKEIREINPIGIILSGGPNSVYDEGSFDIDPEIFELGLPVLGICYGMQLMSYKLGGMVEAAGEREYGVAPLQLTEKSALFAGTPEVQDVLMSHGDRVTAIPEGFHVVGTSPNSPFAAVENTERNLYGIQFHPEVRHSVHGTEMLRNFALNTCGAKGNWSMENFIDMQIKDVREKVGDKKVLLGLSGGVDSSVVGVLLQRAIGDQLTSIFVDHGFLRKGEADQVMETLGGKFGLNIIKVDAQKRFMDKLVGLSDPETKRKIIGNEFVYVFDDEANKLEGVDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRALGTQLGMPDEIVWRQPFPGPGLAIRVLGDLTEEKLETVRESDAILREEIAASGLERDVWQYFTVNTDVKSVGVMGDQRTYDYTLAIRAITSIDGMTADFAQLPWDLLQKISKRIVNEVDHVNRIVYDITSKPPATVEWQ
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GCH1L_MYCTU
Sequence: MSVRLADVIDVLDQAYPPRLAQSWDSVGLVCGDPDDVVDSVTVAVDATPAVVDQVPQAGLLLVHHPLLLRGVDTVAANTPKGVLVHRLIRTGRSLFTAHTNADSASPGVSDALAHAVGLTVDAVLDPVPGAADLDKWVIYVPRENSEAVRAAVFEAGAGHIGDYSHCSWSVAGTGQFLAHDGASPAIGSVGTVERVAEDRVEVVAPARARAEVLAAMRAAHPYEEPAFDIFALVPPPVGSGLGRIGRLPKPEPLRTFVARLEAALPPTATGVRAAGDPDLLVSRVAVCGGAGDSLLATVAAADVQAYVTADLRHHPADEHCRASQVALIDVAHWASEFPWCGQAAEVLRSHFGASLPVRVCTICTDPWNLDHETGRDQA
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: NANK2_ECOL6
Sequence: MITLAVDIGGTKISAALISDDGSFLLKKQISTPHERCPDEMTGALRLLVSEMKGTAERFAVASTGIINNGVLTALNPDNLGGLKEYPLKNIMEDITGLNGSVINDAQAAAWAEYTVLPKEICDMVFITVSTGVGGGIVVNRKLLTGVSGLAGHVGHILSGVTDTECGCGRRGCVEAVSSGRAIMGAAKNKLAGYSTKYIFELARQGYKEAEFLTERSASTIAELIVSLKLLLDCQVVVVGGSVGLADGYVQKVSKHLSIYSEICNVMLFPAYFRSDSGLIGATLWDRDCIT
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: XERC_CHLTE
Sequence: MKRSAPVQFAKKDVANCRWLGEFLVHLESTRNVSAKTVTAYTTDLIQFFEFLTDESGHQEMSAVDPELVEVADVRRFMGDLLDSGIKPRSIARKLASVKSFYRFLLDTGKIERSPLSLVLTPRLERKIPDFLSEEEASRLFDQLVLSDQESVGPEQGQKAAVQRFELARDRAVLELLYGCGLRLSEVTGLENADVDLVHGFLKVTGKGRKQRIVPFGEPAAEALRNYFEVRRNFFRILKEGAGETSKVFVTAKGRQIYPMLVQRMTKRYLSPVTESARKNPHMLRHTFATHMLNGGADLKSVSEMLGHSNLTTTELYTHVTFNRLRDAYTKAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICAA_STAAN
Sequence: MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
What is the function of this protein?
N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Requires IcaD for full activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthase, PNAG synthase, Poly-beta-1,6-GlcNAc synthase, Biofilm polysaccharide intercellular adhesin synthesis protein IcaA, Biofilm PIA synthesis protein IcaA, Intercellular adhesion protein A, N-acetylglucosaminyltransferase IcaA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NOP14_DROME
Sequence: MVAKGKKASADAVYAKKTTRSANPFDNSTAQSSKRGNPFDVHVNKEKFKILGRICKHDRGMPGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIGKHLSGDQLTESVMNARYLAEKMSQVRSNQKAEKFNLNDDELLTHRGQTLEEIEQYRDERSDDEELDDEALDADFTAAAHFGGEGDSAQDRQAAIDEMIVEQKRRKNEIAKEKDEVYDLTEKLDANYKLLLPLVAKVTKDEQDAKPPPDAYDKLLKEMIFEPRGSVADKLINPDELAKQEAARLEKLENERLRRMRADGEEDEEASVAKPKHRSADDLDDGYFLAGEDDEGDDTLAYDLDGNLGTHLNGKKEAVLKGDENEDDDDKEGEEEEEEDSDEESDSEVDNLSDLKESESESEPEEAPKASKKKAKKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHATAQKAIIIERIIKCNHPKLEGVNRENVVKLYSFLLQYLKDLFEDASEQDIREHFQLLSKLMPYLYELTQLNPERMSNTLLEVIKEKYEEFRKNHKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQEISMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVHMSIPKRDVEQLEITPPFERDGPLSKLLALPANTESTKLEPQQLQPTDLVTQTITPDFKVRALDTSLLLIKEALQLVEEHVGACYLAQPFLALLSRLPLESYPEHVHQHHKDATELAEKLAAQKMKPLAPAEKKPKALRLLEPRFEAVYDDKRRPKMSKAKEERAKLLHKIKREKKGAIREIRRDTSFVQMLRLKQTLQSDKERHEKVKRIYQEASVQQGELNELSRAKKKKKF
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
What are the official names of this protein?
Nucleolar protein 14 homolog, Nucleolar complex protein 14 homolog.
What is the protein family that this protein belongs to?
Belongs to the NOP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RSMA_META3
Sequence: MQQNKKLGQCFLKDKNIVKKAINAANINKNDIVLEIGLGKGILTKELAKQCKKVIVIELDKKLEIFWEDIIKEYPNVEIIWNDALKVNLKELGFNKVVANLPYQISSPITFKLLDCDFEVAVLMYQYEFAKRMGAPSGTKEYSRLSVSVQYRAVVDYVCKVSPSAFSPKPKVDSAIVKITKKNEPIHNIDNWEFFDGFNRALFQHRNKNTKKALIHSAHEINMDRDKLKELLNSNEIMEFNDLLGKKVYTLSLKEIGVLCNNLYKIINKSK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CUPPJ
Sequence: MTQVAKNDHRLMQVLLAPVVSEKATLVADKNEQVVFEVARDANKAEVKAAVELLFKVEVQSVQILNQKGKQKRFGRFMGRRNHVKKAYVSLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MRSA_BACSY
Sequence: MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDMEAACTFTLPGGGGVCTLTSECIC
What is the function of this protein?
Kills a number of Gram-positive bacteria.  Acts at the level of cell wall biosynthesis by interfering with bacterial peptidoglycan biosynthesis.  Specifically inhibits the conversion of the lipid II intermediate into polymeric nascent glycan strands by transglycosylation.  May interact with the peptidoglycan precursor rather than with the enzyme.
What are the official names of this protein?
Lantibiotic mersacidin.
What is the protein family that this protein belongs to?
Belongs to the type B lantibiotic family.
Protein: PPNP_ERWT9
Sequence: MLNVSEYFDGKVKSIGFESASAGRASVGVMAEGEYTFATAQAEEMTVVSGSLKVLLTGETDWKWYQAGEAFNVPGHSEFYLQVAEPTAYLCRYLKD
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ABNA_NEOFI
Sequence: MSASAFVAVASCLAALVHGYANPGSCSGACNVHDPALIRRQSDGKYFRFSTGNKISYASSSSIQGPWTVLGSVLPSGSSINLDGKDDLWAPDVSLVNGVYHVYYSVSTFGSQSSAIGLATSSTMDLNSWTDHGSTGIQSSSSKPYNAIDANLFNDGGTYYMNFGSFWHDIYQAPMNSAATAAASSSYNIAYNPSGTHAVEGAFMYKYGSYYYLFFSAGICCGYDTSRPASGEEYKIKVCRSTSATGNFVDASGVACTNGGGTVVLESHGTVYGPGGQGVFTDPSLGPILYYHYVDTTIGYADGQKLFGWNKIDFSSGWPVV
What is the function of this protein?
Endo-1,5-alpha-L-arabinanase involved in degradation of pectin.  Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
What are the official names of this protein?
Probable arabinan endo-1,5-alpha-L-arabinosidase A, Endo-1,5-alpha-L-arabinanase A, ABN A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKG_BORPA
Sequence: MNKPSEVKPVALNVPDYVKHSGLIAWVERIAALTKPDRVVWCDGSQEEYDRLCEQMVQGGTMRRLNPAKRANSYLACSDPSDVARVEDRTFICSEREEDAGPTNNWAAPQAMRETLGGLFDGAMRGRTMYVVPFSMGPLGSPIAHIGVELSDSPYVVVNMRIMTRMGRKVFDVLGSDGAFVPCVHSVGMPLAEGQQDVAWPCNPTKYIVHYPETREIWSFGSGYGGNALLGKKCFALRIASTMGRDEGWLAEHMLILGVTSPKGRKYHVAAAFPSACGKTNFAMLIPPHGMDGWKVTTIGDDIAWIKPGPDGRLHAINPEAGYFGVAPGTSEKTNFNAMAMLKANVIFTNVALTDDGDVWWEGMTDTPPAHLIDWQGQDWTPAIAAETGRKAAHPNARFTAPAAQCPSIDPEWENPKGVAIDAFIFGGRRSTTVPLVTEARNWVEGVYMAATMGSETTAAAAGQQGVVRRDPFAMLPFCGYNMSDYFDHWLKLGRRLEETGATLPRIYCVNWFRKGPDGKFVWPGFGENMRVLRWMLGRLDGQAGGVDQVFGISPAYGDIDWTGLEFSPDKFEQVISVDLPAWRAELALHDELFTQLAARLPEDLPLTRTAIERRMAA
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y984_BURP0
Sequence: MQYEIVSAGEDVDDERARGRRAAAPAAPSSAVPSSAALSSAALSSAAQPTGAPPATAAARRGRDLPRERLLARGPAALSDAELVALLLGSGLPGHDVFALAHTLLARFGSLRALLDAAPDDFKGLRGIGPARTAILVAVVELARRALAEKARERPLVDSPGAVDDYLRLLIGTRPREVFVCLFLDARHRLVQTEETAHGSLTRMAVYPREIVRRALALNAAALIVAHNHPSGAVRPSAADRRLTRVLRDALALVDIKLIDHFVVGASDTFSFAQAGWI
What are the official names of this protein?
UPF0758 protein BURPS1106A_0984.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: GTSF1_HUMAN
Sequence: MEETYTDSLDPEKLLQCPYDKNHQIRACRFPYHLIKCRKNHPDVASKLATCPFNARHQVPRAEISHHISSCDDRSCIEQDVVNQTRSLRQETLAESTWQCPPCDEDWDKDLWEQTSTPFVWGTTHYSDNNSPASNIVTEHKNNLASGMRVPKSLPYVLPWKNNGNAQ
What is the function of this protein?
Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
What are the official names of this protein?
Gametocyte-specific factor 1, Protein FAM112B.
What is the protein family that this protein belongs to?
Belongs to the UPF0224 (FAM112) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3206_GEOMG
Sequence: MPSFDIVSKVDMQEVDNAVNQAVKEIGQRYDFKGSKSEVTLEKDAIKILADDDFRLKAIVDILQSKFIKRGISPKALQYGKAETASGGMVRQIITVQQGISKEKGKEVVAVIKDTKLKVQGQIQDDQVRVTGKNRDDLQEAIRTLKGKDLGIELQFVNFRD
What are the official names of this protein?
UPF0234 protein Gmet_3206.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RFC3_YEAST
Sequence: MSTSTEKRSKENLPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPHLLFYGPPGTGKTSTIVALAREIYGKNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKGFKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDLKAVLKSILEDDWGTAHYTLNKVRSAKGLALIDLIEGIVKILEDYELQNEETRVHLLTKLADIEYSISKGGNDQIQGSAVIGAIKASFENETVKANV
What is the function of this protein?
Component of ATP-dependent clamp loader (RFC and RFC-like) complexes for DNA clamps, such as the POL30/PCNA homotrimer and the checkpoint clamp DDC1:MEC3:RAD17 complex.  During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC.  The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit.  Dissociation of RFC from the clamp leaves the clamp encircling DNA.  Component of the replication factor C (RFC or activator 1) complex which loads POL30/PCNA and acts during elongation of primed DNA templates by DNA polymerase delta and epsilon.  RFC has an essential but redundant activity in sister chromatid cohesion establishment.  Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA.  Component of the RFC-like RAD24-RFC complex which loads the checkpoint clamp DDC1:MEC3:RAD17 complex and is involved in DNA repair pathways.  Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair.  RFC3 supplies a catalytic site to the ATP site of RFC4.
What are the official names of this protein?
Replication factor C subunit 3, Replication factor C3, Activator 1 40 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAD_MOUSE
Sequence: MCAARTPPLALVFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEESSQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHAPQYAFAGSNVDLPLLEWLNKYTFPTEQRFRSTDVAEEVYTRVVRRTLKNGTTTACYFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNDTVPEYKETTEESVKETERFVSEMLQKNYPRVKPIVTPRFTLSCTETLMSELGNIAKTHDLYIQSHISENREEIEAVKSLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNIFSERGASIAHCPNSNLSLSSGLLNVLEVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEKNLTLKEVFRLATLGGSQALGLDSEIGNFEVGKEFDALLINPRASDSPIDLFYGDFVGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
What is the function of this protein?
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
What are the official names of this protein?
Guanine deaminase, Guanase, Guanine aminase, Guanine aminohydrolase, GAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
Protein: OBG_HELPG
Sequence: MFVDSVEIIIASGKGGPGMVSFRREKFVIKGGPDGGDGGDGGDVYFEVDNNTDTLASFRGTKHHKAKNGAPGGTRNCAGKKGEDKIIVVPPGTQVFADDKLWLDLITPKERVLALKGGKGGLGNAHFKSATKQQPTYAQKGLEGVEKCVRLELKLIADIGLVGFPNAGKSTLISTISNAKPKIANYEFTTLVPNLGVVSVDEKSGFLMADIPGIIEGASEGKGLGISFLKHIERTKVLAFVLDASRLDLGIKEQYQRLRLELEKFSPALANKPFGVLLNKCDVVENIDEMAKDFCAFLNLEVQKLEAFDLEPYLGFLHPHLTSDFENDPNEKSALFVLPLSAVSALNTHALKFVLLKALP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_TREPS
Sequence: MDERRLKGKRRVQLGKYAAVRGRKEGRLPAVMYDHRGVSVPLELAQQDFDRLFRALTRSTVLSLELDGGEVFCVFVKDYQHNMVSDRVEHVDFYAVEESVPLRMRIRLQLCGSPEGVRYGARLEKGLSYIEVESLPRNLPDRVVLDISGLGAGDVRRVRDVPLPASVVVLSDPDAVIVALSSSASEAGSPAGARTG
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RL14_OCEIH
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKQATPGGVVKKGEVVKAVIVRSKSGARRKDGSYIRFDENAAVIIRDDKSPRGTRIFGPVARELRDAQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL15_CUPPJ
Sequence: MQLNNLKPAAGSKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLYRRLPKRGFTSLTKAFTAEVSLRDIERLEAAEVDLLVLKQAGLVSDLVKSAKVIKAGELTRKVTIKGLGATAGAKAAIEAAGGQIAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.