PharMolix/UniProtQA huggingface dataset:
Protein: PSBN_MESVI
Sequence: METATIFSIFFSCLLIGLTGYSLYTSFGNASSELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUSB_VIBPA
Sequence: MGASVKPAARRNARQFALQAIYSWQITKENVATIEEQFLSGDKYDEEELRASEPALAAPETDVAYFRELLSGVVLSHAELDSKIRPYVSRPMQDLDMMELALLRLAMYEMTRREDVPYKVVINEAIELAKVFAAEDSHKFVNGVLDKAAPHVRKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: METE_ACICJ
Sequence: MSIATSLGFPRIGRRRELKSALEAHWAGELSEAGLQEAARLLRAESHSLQQGLGIGHIPSNDFALYDHVLDTACMVGAIPPGYGWRGGEVTLPTYFALARGTGGGDAAAGLPALEMTKWFDTNYHYLVPRLAAGQHFAVTANRPLALFREALARHRRTRPVLLGPVSFLLLAKTDDGSDPLDLLDRLLPCYAQVLAELAAEGCAWVQMDEPVLALDLAPKARAALRHAYETLARGATPRLLLASYFAPIADNLPTALALPVAGLHLDLVRGRDDLAPVLAAIGPATWLSLGLVDGRNVWRADLRAALATAREAARALGGSERLMIAPSCSLLHVPVDLAQEDRLDPAIRPWLAFATQKLAEVATIARGLDEGEGAIAEALEASDAALRTRRDSARVHRTDVAARLLGATPEMERRPAPHAARRARQRQRLPLPAFPTTTIGSLPQTSGVRRTRAALARGEIGAAEYDEAIATWTEDAIRLQERIGLDVLVHGEFERNDMVKYFGEQLDGFAFTRHGWVQSYGSRCVAPPIIWGDVARPRPMTVRWARHAQSLTARPVKGMLTGPVTMLQWSFVRDDLPRETVCRQIALALRDEVADLEAAGLAIIQVDEPAFREGLPLRTADREAYLRWAVSCFRLATAVVRDDTAIHTHMCYAEFQDIMPAIATMDADAISIETARSRMELLEAFAGHGPSAYPAEIGPGVWDIHSPRIPPEEEILALLRLARRKLADDQLWVNPDCGLKTRNWREVIPALENLVGAARRLRAEAIPA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: ERLN1_XENTR
Sequence: MAHFGVVVGLMMILVFLVFLSSIHKVEEGHLAVYYRGGALLGGPGDPGYHIMFPFITYFRSVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNMLTPSAVYDVVRNYTADYDKTLIFNKIHHELNQFCSSHTLQEVYIELFDQIDENLKLSLQMELNVMAPGLTIQAVRVTKPKIPEAIRRNFELMESEKTKLLIAEQRQKVVEKEAETERKKAVIEAEKVAQVAKIQYRQKVMEKETEKFISEIEDSAYLAREKAKADAEYYTAQKSADANKLKLTPQYLELIKYQAVSANNKIYFGSNIPTMFFDSSSRSRIEGKSA
What is the function of this protein?
Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs).  Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.  Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
What are the official names of this protein?
Erlin-1, Endoplasmic reticulum lipid raft-associated protein 1, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, SPFH domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Protein: PSD_CHESB
Sequence: MSLADTIRSSLVPIHREGYRFIAAFGIGSVILGLLWEPLFWIGLLLTAWCAYFFRDPQRITPVDDRLVIAPADGIVSSVGPALPPPELGLSGEFTRVSVFMNVFSCHINRAPVRGRISLIEHRPGKFLNADLDKASMENERNSLIIESPYGPVAVVQIAGLIARRIVCWAEAPGEISVGERFGLIRFGSRVDVYLPREARPRVAVGQVSVGGETIIAEFGSNAPPPLVRVS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: XYLT2_RAT
Sequence: MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEPGEKGRQRKPRPLDPGEGSKDTDSSAGRRGSAGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGRQNLSGAAAGEALIGAAGFPQHGDTGSVEGAPQPTDNSFTPKCEIVGKDALSALARASTKHCQQEIANVVCLHQAGNLMPKSVPRHCQLAGKVSPGIQWEEVRAQQPVSGPLVRIAYMLVVHGRAVRQLKRLLKAVYHEEHFFYIHVDKRSNYLYREVVELAQHYDNVRVTPWRMVTIWGGASLLRMYLRSMKDLLETPGWTWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRDNSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTEDPLVAQLRQFYTYTLLPAESFFHTVLENSPACESLVDNNLRVTNWNRKLGCKCQYKHIVDWCGCSPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENIYDMADGPSGLSDVLLTAYTAFARISLRHAATVSPLATAVCRFEPRGLPSSVHLYFYDDHFQGYLVTQAVQPSAQGPAETLEMWLMPQRLLKPLGHSDQASRLQSLEVGTEWDPKERLFRNFGGLLGPLDEPVAMQRWARGPNLTATVVWIDPTYVVATSYDITVDADTEVTQYKPPLSLPLRPGAWTVRLLQFWEPLGETRFLVLPLTFNHKLPLRKDDASWLHAGPPHNEYMEQSFQGLSGILNLPQPEAVEEAARRHTELTGPALEAWTDGELSSFWSVAGLCAIGPSSCPSLELCRLTSWSSLSPDPKSELGPVKADGRLR
What is the function of this protein?
Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity).  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity).
What are the official names of this protein?
Xylosyltransferase 2, Peptide O-xylosyltransferase 2, Xylosyltransferase II.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Protein: PDXH_YERP3
Sequence: MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVVFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MRAY_CARHZ
Sequence: MVITKGVTALLVSFFVALGGGRVLIPWLLKLKIGQTVRTEGPKRHLKKSGTPTMGGIIFLLSLVVTVVVFQAFDAKTLLLLITTLLFGLLGFLDDYLKVVLRRPLGLRAREKLLGQVIFSLVLTFGAVAFLGRGTDWYIPFSRLLLGEPRYLELGNVFFFAATIFIMVGFANAVNLTDGVDGLCSSVTLIVMSFFAMTSLALKEKGLFIFALALMGGLVGFLVYNRHPAKVFMGDTGSLALGAAVAGFAVLTQTELFLLLVGLIYVVETLSVIIQVIVYQLTGKRVFKMSPLHHHFELSGWSENKIVLVFSLVTLIMVLISGYGL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KGUA_RHOBA
Sequence: MNDPSCSSADETAHPGRLVIISGPSGAGKSTVVKQLMKRCDVPLQLSVSATTREPRPGEIHGQDYFFLSHEEFERRRKLNDFVECKQVFSMGQWYGTLKDQVATGLNAGKWVILEIDVQGAMAVLDDPHYRPVTIFVHPGSMEELERRLRNRGTESESSLTARLETAAAEMQCLSRYQYEIINESVDNAVTEICQILLDQRKTTPCSKN
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_DRIGR
Sequence: METATLVAISISGSLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRP5_ARATH
Sequence: MVLQKRPDYGFNGYEVPHTPRAARSPRKSAFKKKSENHQISSFDLLAAVAGKLLLEGGNSSSSSNNTSGNNEDQCAVKKEPLNGGDIMVEEETTNSDHDNNNAERSFFVSEILQKSHEMQSFNRSPSPLKEFHFGSSSGITSDSSEKFETQELAYDESKINNGDCYRSESNDKKSMLGGLNFEAKLSRNVVGKDEKHIGSGFRKPIPQNPSTCSDDVDLHGKENDDGENFSACYRTKSFRSTLRIGDRRIRKVWASKYCKVPPKLKDTTVTNSDLDLKSDYYSKKHCLKSLRSERNYPIKKRRYFDGYTASQSEETNKNEGQSGSPRKASAFLSSIACQKQPAAFQSPRDSNNVKLGIKSFRVPELFIEIPETATVGSLKRTVLEAVTSILGGGLRIGVLVHGKKVRDDSKMLLQTGLSLDTLSDTLGFCLEPNPPQSTKPLSPEDSDFARPCNVPHTLTRCLPSPGKHAKPSNSVESDLDSKPSAPNRGKTIYSRALIPVSPLHAQALTVVPPRKTKRSEVAQRRIRRPFSVAEVEALVQAVERLGTGRWRDVKLRAFDNAKHRTYVDLKDKWKTLVHTARISPQQRRGEPVPQELLDRVLTAHAYWSQQQGKHQLLEGPQQLETSLGL
What is the function of this protein?
Binds specifically to the plant telomeric double-stranded DNA sequences.  At least 6 repeats of telomeric sequences are required for binding.
What are the official names of this protein?
Telomere repeat-binding protein 5, Protein TRF-LIKE 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTP1_DICDI
Sequence: MGSVESSNQMNGSIENKTNKIDISVLRPLPTRSNSSISLSSSSHSSFSRMGSLGSLPTNSGSSSPYYNNSSFDLVDEERIKSSIYNLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQFSIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDATPIDQVVDPFTHLPITEYQSDNLDLKGLGYHFKSSIYNSNGINNNNNNNLNNNNNINNNSNGSNNTPQTEPNNEEDDDDAAESDLKYAIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLNCKLGFSLPHVNNINNYNNYSNTTTTTTSSLASTTIIHPSTNSKLN
What is the function of this protein?
May have a role in growth and in the early stages of development.  Affects the timing of development.
What are the official names of this protein?
Tyrosine-protein phosphatase 1, Protein-tyrosine-phosphate phosphohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Might be tethered to the plasma membrane.
Protein: HEM1_DELLE
Sequence: METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSASAVLCQQVKETPPANEKDKTAKAKVQQAPDGSQQTPDGTQLPSGHPSLAASQGTASKCPFLAAQMSQGGSSVFCKASLELQEDVQEMHAVREEVAQTSVNPSVISVKTDGGELSGLLKNFQDIMRKQRPEGVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQFFPMADDYSDSLVTKKQVSVWCSNDYLGMSCHPRVCGAVMDTLKQHGTGAGGTRNISGTSKFHVDLEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIWNSRVPKYIYRHNDVDHLRELLQRSDPAVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGAQGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTIRSYAAGFIFTTSLPPMLLAGALESVRILKSTEGRVLRRQHQRNVKLMRQMLMDASLPVVHCPSHIIPVRVADAAKNTEVCNELMSRHNIYVQAINYPTVRRGEELLRIAPTPHHTPQMMNYFVENLLATWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKSYFFGMSKLVSAQD
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: MYBY1_SORBI
Sequence: MGRAPCCDKVGLKRGRWTAEEDQILANYIAEHGEGSWRSLPKNAGLLRCGKSCRLRWINYLRADVKRGNISKEEEDIIIKLHATLGNRWSLIASHFPGRTDNEIKNYWNSHLSRQIHTYRRKYTAAPDTTVIIDMSKLHSAEKRRGGRTPGWSPKSSSANTTTNTTSSKTNKSKETDPGPGLKSACDAKGASSPPTAATTTSAASSPRHSDGARSAVVDPDPNQPNSSSGSTAEGPCSGEDATGPWELDPIDLGDLWEAESEIDALMSMDAPLEGFDAVVGEAQAQVDDLFDMDMDWDGFAAHLWGGPEQNDHIAELQQAAEPQATAAACTPNEHEPQVAAAAAACTPDEHEPQAAAAAAAATCTPDEHGLEAFETWLLSDSF
What is the function of this protein?
Transcription factor involved in regulating the biosynthetic pathway of flavan-4-ol-derived red phlobaphene and red-brown 3-deoxyanthocyanidin (3-DA) pigments (Ref. 4, Ref. 3, PubMed:25647576, PubMed:30911880).  Regulates transcription of chalcone synthase, chalcone isomerase, dihydroflavonol reductase and flavonoid 3'-hydroxylase genes required for the phlobaphene and 3-DA biosynthesis (PubMed:16429259, PubMed:20083611).  Transcription of these genes is activated in mesocotyls in response to ingress of non-pathogenic fungus C. heterostrophus (PubMed:20083611).  Regulates the production of 3-DA phytoalexins (luteolinidin, 5-methoxyluteolinidin, apigeninidin and 7-methoxyapigeninidin) in mesocotyls in response to C. heterostrophus and corn leaf aphid (CLA) R. maidis (Ref. 3, PubMed:20083611, PubMed:30911880).  Involved in resistance against anthracnose leaf blight (ALB) caused by the pathogenic C. sublineolum fungus by inducing the production of 3-DA phytoalexins (PubMed:20083611, PubMed:25647576, PubMed:30911880).  Confers resistance, also by inducing the production of 3-DA phytoalexins, against CLA R. maidis, which is an insect and a pest (PubMed:30911880).
What are the official names of this protein?
Transcription factor Y1, Myb-related protein Y1, R2R3 MYB transcription factor Y1, Yellow seed1.
Protein: APR2_ARATH
Sequence: MALAVTSSSTAISGSSFSRSGASSESKALQICSIRLSDRTHLSQRRYSMKPLNAESHSRSESWVTRASTLIAPEVEEKGGEVEDFEQLAKKLEDASPLEIMDKALERFGDQIAIAFSGAEDVALIEYARLTGKPFRVFSLDTGRLNPETYRLFDAVEKQYGIRIEYMFPDAVEVQALVRNKGLFSFYEDGHQECCRVRKVRPLRRALKGLKAWITGQRKDQSPGTRSEIPIVQVDPVFEGLDGGVGSLVKWNPLANVEGADVWNFLRTMDVPVNALHAQGYVSIGCEPCTRPVLPGQHEREGRWWWEDAKAKECGLHKGNIKEEDGAADSKPAAVQEIFESNNVVALSKGGVENLLKLENRKEAWLVVLYAPWCPFCQAMEASYIELAEKLAGKGVKVAKFRADGEQKEFAKQELQLGSFPTILLFPKRAPRAIKYPSEHRDVDSLMSFVNLLR
What is the function of this protein?
Reduces sulfate for Cys biosynthesis.  Substrate preference is adenosine-5'-phosphosulfate (APS) >> 3'-phosphoadenosine-5'-phosphosulfate (PAPS).  Uses glutathione or DTT as source of protons.
What are the official names of this protein?
5'-adenylylsulfate reductase 2, chloroplastic, 3'-phosphoadenosine-5'-phosphosulfate reductase homolog 43, PAPS reductase homolog 43, Prh-43, Adenosine 5'-phosphosulfate 5'-adenylylsulfate sulfotransferase 2, APS sulfotransferase 2, Thioredoxin-independent APS reductase 2.
What is the protein family that this protein belongs to?
Belongs to the APS reductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLSX_AKKM8
Sequence: MKIALDVMGGDNAPDINVDGAKRALQDFPLIEKIYLVGREETVRSSCDRWGLSGPRVEIVPAAEVVEMNESGLLAVRKKKNSSMSISVDLVKSGDADAVVSAGNTGAAVAAATVKLRLLDGVERAGIVTQLPNEFGVCNVTDTGANPDAKPRHLVGYAVMASILARSVYGKQMPKVGVMSNGSEDEKGTDFTKGTFCLLKHLEERGALPFKFVGNVEGHDLFEHEIDVALTDGFTGNVLLKTCEATAKAFSKWLKEELKANPFRMVGAACASGAFRAMKARLSADSVGGSPLLGVRGVTIIAHGSSTPVAIRNALRVSMEMVQQGVNPLIEEEMARLGTIPEVAEVYPK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CBPC2_MACFA
Sequence: MFPALETHLKQTIPDPYEDFMYRHLQYYGYFKAQRGSLPNSATHQHVRKNNPQYLLHGSLGGKDDLIPDTLQKEKLLWPTSLSSAVHRQIEAINRDSHMLSLPHLRSRQLLYDELDEVNPRLREPQELFSILSTKRPLLAPRWPIECEVIKESIHHIEWAPPQPEYFYQPKGNEKVPEIVGEKKGTVVYQLDSVPTEGSYFTSSRVGGKQGIIKELAVTLQGPEDNTLLFESRFECGNLQKAVRVDTYEYELTLRTDLYTNRHTQWFYFRVQNTRKDATYRFTIVNLLKPKSLYTVGMKPLLYSQMDANTRNIGWRREGNEIKYCKNNMDDGQQPFYCLTWTIQFPYDQDTCFFAHFYPYTYTDLQCYLLSVANNPIQSQFCKLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVHPGESNGSWVMKGFLDFILSNSPDAQLLRDIFVFKVLPMLNPDGVIVGNYRCSLAGRDLNRHYKTILKESFPCIWYTRNMIKRLLEEREVLLYCDFHGHSRKNNTFLYGCNNNNRKYWLHERVFPLMLSKNAPDRFSFHSCNFKVQKCKEGTGRVVMWRMGILNSYTMESTFGGSTLGSKRDTHFTIEDLKSLGYHVCDTLLDFCDPDQTKFTQCLAELKELLRQEIHKKFHELGQDVDLEESWSDISLSDIESSTSGSDSSLSDGLPVHLANIADELTQKKMFKKKKKKSLQTRKQRNEQYQKKNLMWKLKLTEDTSEFASTLQKHPAFFKNSESSSFLPMRNENPRLNETNLNRRDKDTSLDPSMTTLILPKNKGRMQTNLNRRDKDTSLDPSMTTLILPKNKGRMQVLHLIYCI
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein.  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate.  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
What are the official names of this protein?
Cytosolic carboxypeptidase 2, ATP/GTP-binding protein-like 2, Protein deglutamylase CCP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with gamma- tubulin in the centrioles and with glutamylated tubulin in the basal bodies of ciliated cells.
Protein: ATP6_CAEBR
Sequence: MNQVYFLDIFMFVFVLQFLFYFKEGMLNTLVKKFLNSLVGVFSYSNTLPLSSVISVFTFIILLTCCFGGYFTYSFCPCGMVEFTFVYAAVAWLSTLLTFISSEKFSVYMSKPGDTYLKTLSMLLVEIVSEFSRPLALTVRLTVNIMVGHLISMMLYQGLELSMGDQYVWLSIFAIMMECFVFFIQSYIFSRLIFLYLNE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: P60_LISWE
Sequence: MNMKKATIAATAGIAVTAFAAPTIASASTVVVEAGDTLWGIAQSKGTTVDALKKANNLTSDKIVPGQKLQVTEVASEKTEKSVSATWLNVRSGAGVDNSIVTSLKGGTKVTVEAAESNGWNKISYGEGKTGYVNGKYLGDAVTSAPVAKQEVKQETTKQTAPAAETKTEVKQSTPAPTAPKAAETKTAPVVDTNATTHTVKSGDTIWALSVKYGASVQDLMSWNNLSSSSIYVGQKIAVKQSAAKTAAPKAEVKTEAPAVEKETSTPVVKENTNTTVKKEVTTQTQTNTTKAPAQAAKPAPAPAPAPTVNTNASTYTVKSGDSLSKIANTFGTSVSKIKALNNLTSDNLQVGTVLKVKGTVPTTNTNNNSNTTAPTTNTSNNNTSSNTSTPSKNTNTNTNQGSSNSASASALIAEAQKHLGKAYSWGGNGPTTFDCSGFTSYVFAKSGISLPRTSGAQYASTSRISESQAKPGDLVFFDYGSGIAHVGIYVGNGQMINAQDNGVKYDNIHGSGWGKYLVGFGRV
What is the function of this protein?
This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria.
What are the official names of this protein?
Probable endopeptidase p60, Invasion-associated protein p60.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: TX31_ANDCR
Sequence: ADVPGNYPLDTRGYSYYCTKLGENEFCKKICKIHGVSYGYCYNSYCWCEYLEGKDINIWDAVKNHCTNTNLYPNGK
What is the function of this protein?
Binds to sodium channels (Nav) and affects the channel activation process.
What are the official names of this protein?
Toxin Acra III-1.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_STRM5
Sequence: MTQPLHVIILAAGAGKRMKSVLPKVLQPIAGQPMLAHVIAAARELEPAAIHVVYGHGGEAVRQHFAGQPDLQWAEQAQQLGTGHAVAQAMPQVPDAAQVLVLYGDVPLIRAQTLRDLLAQPGRLAVLVAEMDDPTGYGRVLRDAEGKVGSIVEQKDANDDQLRVRTINTGIIAAESTALRRWLSQLSNSNAQGEYYLTDVFAFAAHEYTPAEMALVADAQEAEGANDPWQLSQLERAWQRRAVRALCAQGARVRDPARLDIRGTVSVGNDVLIDVDVVLEGNIVLGDGVTIGPFNRLKDVNLGPGTEVRAHCDLEGVITEGAAQVGPFARLRPGTVLADGVHVGNFVETKKVTLGVGSKANHLTYLGDAVIGSKVNIGAGTITCNYDGVNKSTTTIGDNAFIGSNSSLVAPVTIGDSATIAAGSVITRDAPDGKLTLARARQETIDGWKRPLKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCRLA_HUMAN
Sequence: MKLGCVLMAWALYLSLGVLWVAQMLLAASFETLQCEGPVCTEESSCHTEDDLTDAREAGFQVKAYTFSEPFHLIVSYDWLILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSALGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPETASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKLPLQRSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHSGSYWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNPAPQKSAAPGTAPEEAPGPLPPPPTPSSEDPGFSSPLGMPDPHLYHQMGLLLKHMQDVRVLLGHLLMELRELSGHRKPGTTKATAE
What is the function of this protein?
May be implicated in B-cell differentiation and lymphomagenesis.
What are the official names of this protein?
Fc receptor-like A, Fc receptor homolog expressed in B-cells, Fc receptor-like and mucin-like protein 1, Fc receptor-like protein, Fc receptor-related protein X, FcRX.
Protein: RISB_PARXL
Sequence: MEIGQYQPNLDGDGLRIGIVQARFNEPVCNGLADSCIEELERLGVTGEDVLLVTVPGALEIPLALQKLAESAQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGIPVANAVLTTENDEQAVARMTEKGRDAARVAVEMANLAVALEQLGGDDDEEEDEEEEA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PEMT1_DICDI
Sequence: MIVEHAIDYIDYLMNYVDFTEKYFLLTIACVVFNPTWWNITARMEYKTKFMTKICGSKENGCYLLAFLIFSLGILRDWLFSEALIRQPIFQEFDRFEVEVLSYILYGFGGILVLAAYLKLGITGTYLGDYFGILMKERVTGFPFNVMNNPMYNGSVMLFIAHALSYKSVAGLVLSFVVYVVYKFALIFEESFTNYIYSTAAANAAKKNKSKSK
What is the function of this protein?
Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase A, PEAMT, PEMT, Phospholipid methyltransferase A, PLMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.