PharMolix/UniProtQA huggingface dataset:
Protein: ADHX_HORSE
Sequence: MSAEVIKCKAAVAWEAGKPVSIEEVEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGSFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPQTNLCQKIRTTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGVSTGYGAAVNTAKVEPGSTCAIFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFAKAKEFGASECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESIPKLVSEYMSKKIKVDEFVTHSLSFDQINEAFELMHAGKSIRTVVKL
What is the function of this protein?
Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.  Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate.  Class-III ADH is remarkably ineffective in oxidizing ethanol.  Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage.
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase 5, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACE1_BOVIN
Sequence: MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
What is the function of this protein?
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.  Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.  Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.  Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens.  May also act as a transcription regulator via its interaction with RARB.
What are the official names of this protein?
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum. Note=A significant portion localizes to the endoplasmic reticulum. Targeted to Golgi membrane via its interaction with Rab proteins.
Protein: RL17_ACAM1
Sequence: MRHRCRVHKLGKPADQRKALLRSLSTQLIRHGRVTTTKARAKAVRSQVEKMITLAKDGSLASRRQALGYIYDKQLVHALFDQVADRYGDRNGGYTRIIRTIRRRGDNAEMAIIELT
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: BPT_METFK
Sequence: MTLPGEQHLHKIQFYATTAYSCGYLADKPAQSLIATPHHLIDAHAYSGLIQLGFRRSGKFAYRPHCETCHACIPVRLPVAEFQPSRSQRRAWKQHRNLSVALIELAFSEEHFALYSAYQAARHEGSSEDPETVEQYRNFLVQSNVESLMVEFRENGVLKMVSVVDIVRDGISAVYTFYDTADKHASYGTYNILWLLDWCGSLNLPYLYLGYWIKESRKMAYKQNFLPQEGLIDGEWRPIHTERYAQPK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_PSEPG
Sequence: MTDQQTNGAAAEDNSPQFSLQRIYVRDLSFEAPKSPQIFRQTWEPSVALDLNTKQKALEGDFHEVVLTLSVTVKNGDEVAFIAEVQQAGIFLIANLDAPSMSHTLGAFCPNILFPYARETLDSLVTRGSFPALMLSPVNFDALYAQEMQRMQEAGEVPTVQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SYNP2
Sequence: MSDAPPTRLAQLRSQLQKAAYAYYVLDAPFMEDAVYDQLYRELVALETAHPQLITPDSPTQRIGDQPATQFTSVKHNIPLYSLENAFDFGELTQWEQRWQRALAGEIPSDSGYVCELKIDGSAIALTYENGILVRGATRGDGVTGEEITQNLRTIRTIPLRLNLDNPPPLVEVRGEAFLPLETFEKINQEREKAGENLFANPRNAAAGTLRQLDSRIVAARKLDFFAYTLHLPESHNSPQLNSQWEALEFLKKMGFRVNPNRELCPNLTAVKNYFEKWDEGRKKLPYLTDGVVVKLNDFSLQAELGFTQKFPRWAIALKYAAEEAPTTVKDIIVNVGRTGAVTPMAVMEPVQLAGTTVQRATLHNEDRIKELDLRIGDTVVIRKAGEIIPEVLRVLVDLRPEATIPYEFPSHCPECNSALVRPPGEAVARCVNSSCPAILRGSLVHWAGRDALDIQGLGEKNVILLIEHGLVQSIADIYDLTSEQLQSLPRMGQKSAANLIQAIAHSKNQDYARVLYGLGIRFVGKVNAEILAQNFPTLEQLQKASFAQLQGVYGIGEEIAQSVVDWFRVDANQQLIEKLQQAGLTFAQTQTAQTQTAQTQANHQISGKTFVITGTLPTLKRTEAAEKIKAAGGKVTSSVSKNTDYLVAGDNAGSKLDKARQLGIQELNENQLLELLV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: 5HT1E_HUMAN
Sequence: MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, S31, Serotonin receptor 1E.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLHC_SERMA
Sequence: MMVEKSIVQEAKDIQLAMELISLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNIHSSMFYNAYLFLMKSGQCSGVEAVIKAYRLYLEQCPQQAGEAPLLALTRAWTLVRFVDSGMLQLSACSCCGGAFITHAHQPLNGFICSLCQPPSRAVKRRKLSPQLADIIPQLLDEQVKRAI
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIMP3_CHICK
Sequence: MTAWLGFLAVFLCSWSLRDLVAEACTCVPIHPQDAFCNSDIVIRAKVVGKKLMKDGPFGTMRYTVKQMKMYRGFQIMPHVQYIYTEASESLCGVKLEVNKYQYLITGRVYEGKVYTGLCNWYEKWDRLTLSQRKGLNHRYHLGCGCKIRPCYYLPCFATSKNECIWTDMLSNFGHSGHQAKHYACIQRVEGYCSWYRGWAPPDKTIINATDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.  May form part of a tissue-specific acute response to remodeling stimuli.
What are the official names of this protein?
Metalloproteinase inhibitor 3, 21 kDa protein of extracellular matrix, Tissue inhibitor of metalloproteinases 3, TIMP-3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: FABZ_RICCN
Sequence: MIIDITEIMDWIPHRYPFLLVDRVLKIDPNKSITGIKNVTVNEPQFTGHFPARPVMPGVLMVEAMAQLAAILVAKSLGSTKNKEVFLMTIENAKFRRIVQPGDTMHIHAVIDQQRANVWKFSSTVTVEGEIATESKFTAMIKDKT
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_NEIMF
Sequence: MKTFALILADGQASRMGGEDKGLALLGGKALIDHVIDRVRPQVSHIAISTNRNLEEYARRSPHIFPDARQWQHFGPLSALCTAANDLQLATADWLLVVPCDMPYLPGDLVARFETVSKRTPLCNAYYVETPITMHYNIMYIRPQILQSAIPYLFSGMKTLRSWLQQQRARPVRFEFDGHFADLNTQIDLQEG
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CORK4
Sequence: MLDVNLFDELRIGLATADDIRRWSHGEVKKPETINYRTLKPEKDGLFCERIFGPTRDWECACGKYKRVRYKGIVCERCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAANIITSVDEEARHTDQETLEADIFMEKKEVEADRDEELAERQQKLEEDLKELESNGAKADAKRKVQNAAEREMRHIRERAEREIDRLDEIWNTFIKLAPKQMIVDETIYSELVDRYEDYFTGGMGAEAIQTLIKNFDLEAEAEKLSEVIRDGKGQKQVRALKRLRVVAAFLRSGNDPAAMVLDAIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRMIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIIVGPQLKLHQCGLPKLMALELFKPFVMKRLVEKSYAQNIRSAKRMVERQRPEVWDVLEEAIAEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIQLHPLACEAFNADFDGDQMAVHLPLSAEAQAEARVLMLASNNILSPASGKPLAMPRLDMVTGLYFLTLEKSEDQLGGEGAYHEADENGPKRGTYSSFAEALMARDRGVLGLQAPIEVRISHLRPPEDIEAELFPDGWQRGQKWTAHTTLGRIMFNELLPWNYPFVNGVMAKKAQAVIINDLAARYPMITVAQTVDKMKDAGFYWATRSCVTISMDDVLVLPNKEEILQRYEKQAATIEKKLARGKINNEERYRSLVDLWKECTDFVGESVEKIYPDDNPIPMIVKSGAAGNMRQIWTLAGMKGMVTNSRGDYITRPIKTSFREGLSVLEYFNNSHGSRKGLADTALRTADSGYLTRRLVDVAQDVIVREDDCGTRKGLEVDVAKPVLDAEGNETGEFTRAEFLETALIGRYLAKDAVNDNGDVIYERGAFVGDAEAKKMVAEGVRTATVRTVMMCETATGVCATCYGRSMATGQKVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGGDITGGLPRVQELFEARVPKNQAPIASTEGTIKLEDDGNFYTLTITPDNGEDEVVYEKLSKRQGLAVTQEPGGFEHQLRTGDHVVTGQPLLRGAPDPHEVLRVEGVTGVQKHLIEQVQKVYRDQGVAIHDKHIEIIVRQMLRRLTVVDSGSTELLPGSLIDRNEARAINKAVATNGGEGAAFRQEIMGITKASLATESWLSAASFQETTRVLTDAAINKRSDKLIGLKENVIIGKLIPAGTGISRYRNISVEPTEEARAQAFSMNTSYGDGFYGEDGAYGEFTGAAVRLDDQGFDGGFGDIS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UREF1_PSESM
Sequence: MNTLSSLLLALQQADSFFPGGAVAWSWGLETLVADGRLGAGERVTARRRQRAVRLDRSAAVRGFVEGQLRHRWHSFDRVFLLAAWNAADDVSALTNLDAQIEALTLAKELRQGSRRVGQALLGVHVALGTPGAAAYQQQVRAGNTPGHLPVLQGLLWNRLGMHREHCQLAAAHGLCTGLVSAAVRLGVMGHIDAQRVLTDIQPLITELLALEPPEPEDACGFTPMAEIAVMRHETQDLRLFAN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF 1.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_AMBTC
Sequence: MKNVTDSFVSLGHWPSAGSFGFNTDIFATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILSTIRNSEELRGGAIEQLEKARARLRKVEIEADEFRVNGYSEIEREKSNLINAAYENLERLENYKNESIHFEQQRAMNQVRQRVFQQALQGALETLNSYLNSELHLRTISANIGMLGTMKNITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y651_STRP2
Sequence: MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVPTQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR
What are the official names of this protein?
UPF0298 protein SPD_0651.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERT_SALTI
Sequence: MSEPQNGRGALFAGGLAAILASTCCLGPLVLVALGFSGAWIGNLTVLEPYRPLFIGAALVALFFAWKRIYRPVQACKPGEVCAIPQVRATYKLIFWIVAVLVLVALGFPYVVPFFY
What is the function of this protein?
Involved in mercury resistance.  Probably transfers a mercuric ion from the periplasmic Hg(2+)-binding protein MerP to the cytoplasmic mercuric reductase MerA.
What are the official names of this protein?
Mercuric transport protein MerT, Mercury ion transport protein.
What is the protein family that this protein belongs to?
Belongs to the MerT family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XB34_ARATH
Sequence: MGQQQSQSKDEMLFQEVSNNNVEGIKSLHHEGAGLEGVDKLGRTPLILACTNDDLYDVAKTLLELGSNVNAYRSGCNGGTPLHHAAKRGLVHTVKLLLSHGANPLVLDDDVKTALEVARDEGYSNVVRAIESHICLFSGCMREYSGSSLLNLFAPQLLSRKVWVVVVPTGSRNPTKPLKLELVLYDSIQDAQPRMVIPLWKANLEEPKSFRCDDSVMIIDDSRSPKSMRQRRESGFISQARRWAQVDRQIRLKLAAEIKGDMKQMNWFSEACKGVPQPMNPPRFMKTSQATTTTTNVPALSDDALTRVAMSLPSPKTANKEDGLCVICVDAPSEAVCVPCGHVAGCISCLKEIENKKMGCPVCRANIDQVIKLYHV
What is the function of this protein?
No E3 ubiquitin-protein ligase activity observed when associated with the E2 enzyme UBC8 in vitro.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase XBAT34, Ankyrin repeat domain and RING finger-containing protein XBAT34, Protein XB3 homolog 4, RING-type E3 ubiquitin transferase XBAT34.
Protein: RS18_STREM
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HIS1_NITEC
Sequence: MPDITIALSKGRIFEDTIPFLEAAGIIPQDDPDTSRKLIIETNRPDVRLVMVRATDVPTYVQYGAADLGVAGKDVLLEHDGVGLYQPLDLKIARCHMMVAVRDGYDYASAVFQGARLRVATKYVKTARSHFAAKGMHVDLIKLYGSMELAPLVDLADAIVDLVSTGGTLKANRLQAVEEIMPISARLIVNQAALKLKNPTIQPLLEAFNAAIPANV
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPR_RAT
Sequence: MTCQKFYVVLLHWEFLYVITALNLAYPTSPWRFKLFCAPPSTTDDSFLSPAGVPNNTSSLKGASEALVEAKFNSTGIYVSELSKTIFHCCFGNEQGQNCSALTGNTEGKTLASVVKPLVFRQLGVNWDIECWMKGDLTLFICHMEPLLKNPFKNYDSKVHLLYDLPEVIDDLPLPPLKDSFQTVQCNCSVRECECHVPVPRAKVNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLRMEVTDDGNLKISWDSQTKAPFPLQYQVKYLENSTIVREAAEIVSDTSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSLPQLFTTQDVMYFPPKILTSVGSNASFCCIYKNENQTISSKQIVWWMNLAEKIPETQYNTVSDHISKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITINTGLLKVSWEKPVFPENNLQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRIMDGDITKKERNVTLLWKPLMKNDSLCSVRRYVVKHRTAHNGTWSQDVGNQTNLTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSKVNAVQSLSAYPLSSSCVILSWTLSPNDYSLLYLVIEWKNLNDDDGMKWLRIPSNVNKYYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDDIAKQQNDAGLYVIVPIIISSCVLLLGTLLISHQRMKKLFWDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLLEPEPVSEEISVDTAWKNKDEMVPAAMVSLLLTTPDSTRGSICISDQCNSANFSGAQSTQGTCEDECQSQPSVKYATLVSNVKTVETDEEQGAIHSSVSQCIARKHSPLRQSFSSNSWEIEAQAFFLLSDHPPNVISPQLSFSGLDELLELEGNFPEENHGEKSVYYLGVSSGNKRENDMLLTDEAGVLCPFPAHCLFSDIRILQESCSHFVENNLNLGTSGKNFVPYMPQFQSCSTHSHKIIENKMCDLTV
What is the function of this protein?
Antagonizes Isoform A and isoform B-mediated LEP binding and endocytosis.
What are the official names of this protein?
Leptin receptor, LEP-R, OB receptor, OB-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane. SUBCELLULAR LOCATION: [Isoform E]: Secreted.
Protein: OBG_RALSO
Sequence: MKFIDEARIEVIAGDGGNGSASMRREKFVPFGGPDGGDGGRGGSVWAVADRNINTLIDYRFAKKHLARNGENGRGSDCYGAAGEDITLRLPVGTAIYDADTDEQIADLTLDGQRLCLARGGEGGWGNIHFKSSTNRAPRQKTDGKPGERRNLRLELKVLADVGLLGMPNAGKSTLITAISNARPKIADYPFTTLHPNLGVVRTGPSKSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTRVLLHVVDLAPFDEGIDPVAEAKAIVGELKKYDAELYDKPRWLVLNKLDMVPEDEREARVKDFIKRFKWKGPVHRISALTHDGCPGLIHAIQDYLDTLRAEEEAAAAAPDARLDPTLHNVDHDGSANA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_SCLS1
Sequence: MASIVPRFRCLNAPPLRQTSRNILAIPTATSRSFATEIDVSKPTPIVKRRPTYFKDKINAVPSFSEFVGLPEKAFTPEDALELRTAMVGPPGKKRQITRLPEWLKTPIPDNSNYKKIKKDLRGLNLHTVCEEARCPNISDCWGGSDKSAATATIMLMGDTCTRGCRFCSVKTSKAPPPLDPHEPEHTAEALSRWGLGYVVLTSVDRDDLADGGARHFAETIMKIKQKKSSILVEALTGDYGGDLEMVKLVAESGLDVYAHNMETTEELTPFVRDRRAKYRQSLKVLEAAKKAKPSLITKTSIMLGLGETEEALWQALRDLREVDVDVVTFGQYMRPTKRHMKVEEYVTPEVFEIWRQRALDLGFLYCASGPLVRSSYKAGEAFIENVLKKRKGVTILSDEATGMDKAIV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS252_ARATH
Sequence: MAPKKDKVPPPSSKPAKSGGGKQKKKKWSKGKQKEKVNNMVLFDQGTYDKLLTEAPKFKLITPSILSDRMRINGSLARRAIRELMAKGLIRMVSAHSSQQIYTRATNT
What are the official names of this protein?
40S ribosomal protein S25-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: PYRF_CANAL
Sequence: MTVNTKTYSERAETHASPVAQRLFRLMESKKTNLCASIDVDTTKEFLELIDKLGPYVCLIKTHIDIINDFSYESTIEPLLGLSRKHQFMIFEDRKFADIGNTVKKQYIGGVYKISSWADITNAHGVTGNGVVEGLKQGAKETTTNQEPRGLLMLAELSSVGSLAYGEYSQKTVEIAKSDKEFVVGFIAQRDMGGQEEGFDWLIMTPGVGLDDKGDGLGQQYRTVDEVVSTGTDIIIVGRGLFGKGRDPDIEGKRYRDAGWNAYLKKTGQL
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: IXTPA_CALS4
Sequence: MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRDKVKEGIVISDDTGLFVEYLGGQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYFKTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFFVDGIGKTLAELSLEEKNKISHRGKALLKLKEYILKRLEEN
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SYP_HALSA
Sequence: MSDDDQELGITESKEHSPGDWYAEVVQKAGLADYAPMGGFIVTRPRGYALWEAIQDNLDGWFKDTGVENAYFPMFIPEDYLEREKDIVEGFDPEVAWVTQGGHDDLDQRLAVRPTSESIIAPYLSQWVRSHRDLPLRVNQWNSVVRWEATETKPFFRTKEFLWQEGHTAHATDEAAWAETTLRLDQYHRLYEDVLGIPVLRGRKPDHDKFPGADTTMSVEALMPDGKSVQGGTSHHLGQSFADAFDITFADEDEAERTAYTTSWGLSWRAIGALVMSHSDDQGLVLPPTVAPKQVVIVPIWQEDTKDDVEQYGAEIAAELEAQGVRVHFDDRDGRNPGFKFNEWELNGVPVRFEIGPNEVEDDEVTVVHRPDGESTVEDRAAIADRVHDHLDEVYDKLYDAAADRLAENVREADNRADILGTIGQHGGYVKAPWCGDQDCEAEIKDQIAAEIVMVPLGEDSAARAASELEGERVPEPDHDGEDCAICGDEATRTAYFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1111_PYRAE
Sequence: MEFSVGGVEVVLMRGDITEVEADAIVNAANSYLEHGGGVAGAIVRKGGQVIQEESREWVRKHGPVPVGDVAVTSAGRLKAKYVIHAVGPRCGVEPIEKLAEAVKNALLKAEELGLVSIALPAISTGIFGCPYDAAAEQMATAIREVAPALRSIRRILVVLYGEEAYQKFLEVFKKHLPGGRL
What are the official names of this protein?
Uncharacterized protein PAE1111.