PharMolix/UniProtQA huggingface dataset:
Protein: MDH_FRATM
Sequence: MARKKITLVGAGNIGGTLAHLALIKQLGDVVLFDIAQGMPNGKALDLLQTCPIEGVDFKVRGTNDYKDLENSDVVIVTAGVPRKPGMSRDDLLGINIKVMQTVGEGIKHNCPNAFVICITNPLDIMVNMLQKFSGVPDNKIVGMAGVLDSARFRTFLADELNVSVQQVQAYVMGGHGDTMVPLTKMSNVAGVSLEQLVKEGKLKQERLDAIVSRTRSGGGEIVALLKTGSAYYAPAAAGIQMAESFLKDKKMILPCAAKVKAGMYGLDEDLFVGVPTEISANGVRPIEVEISDKEREQLQVSINAVKDLNKVAAEILAK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: CYTB_BOVIN
Sequence: MMCGGTSATQPATAETQAIADKVKSQLEEKENKKFPVFKALEFKSQLVAGKNYFIKVQVDEDDFVHIRVFESLPHENKPVALTSYQTNKGRHDELTYF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-B, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I43A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIGGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEFEDLTFLARSALILRGSVAHKSCLPACVYGPAVASGYDFEREGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGKLSTRGVQIASNENMETMGSSTLELRSRYWAIRTRSGGNTNQQRASAGQISIQPTFSVQRNLPFDRTTIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKAANPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HEM3_STRM5
Sequence: METVRIATRKSPLALWQSEHVADRLRQAHPGLHVELVPMSTRGDEVLDRSLAAIGGKGLFLKELELAMLRGEADCAVHSLKDVPMELDEPFALPAMLTRHDPADGFVSNLYASLDALPIGARVGTSSLRRQAQLRALRPDLQLLDLRGNVNTRLAKLDNGGYDAIVLAVAGLERLGLGERIVARLQPPQWLPAPAQGAVAVECDGSNARLMALFAGLDDAATRACVEAERAMNRALHGSCHVPVAAIAQWQGQDLHLQGLVGSASDGRAVRAEAVGPASDPEVLGQRVAKMLLDAGAGELLNV
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: Y097_MYCTU
Sequence: MTLKVKGEGLGAQVTGVDPKNLDDITTDEIRDIVYTNKLVVLKDVHPSPREFIKLGRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTGAFWHIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGTVSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEILYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA
What are the official names of this protein?
Putative dioxygenase Rv0097.
What is the protein family that this protein belongs to?
Belongs to the TfdA dioxygenase family.
Protein: PROB_ECO45
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_BAUCH
Sequence: MKKLAEFYRGKAKTVYHTSHPSFLILEFRNDISILDGQCIKQFDRKGMINNKFNFFIMNKLAELGIPTQIEQLLSDNETLVKKLDMIPVECVIRNRAAGSLVRRLGIEEGQILNPPLLELFFKNDSMHDPIINASYCTTFNLVSDTNLVRMQQLTKHANNILTKIFDKKGIILVDFKLEFGLFNNQIILGDEFSPDVSRLWDKKTLKKMDKDRLRQNLGGVIEAYEEVAIRIGVSLT
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RUVC_SHEFN
Sequence: MAIILGVDPGSRITGYGVIQCQGRQQIYLGSGCIRTSADDLPQRLQQIYAGLCEIITQYKPDEFAIERVFMAKNADSALKLGQARGAAIVAATCAGLPVAEYSATQIKSAVVGTGRAQKTQVQHMIKQLLKLPASPQADAADALGVAICHFHTYQSLIAMGGKASSRTYGRYK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: LLDD_BARQU
Sequence: MIISSTFDYRKAAKRRLPPFLFHYIDGGAYAEETMRRNYADLQALALRQRILRQVGEVDLSIKLFDQRLNLPIVLAPVGLTGMYARRGEVKAARAAVAKGIPFTLSSVSVCSLAEVHAEVGSGFWFQLYVLKDRGFMRDVLERSWLAGVRTLVFTVDMPVPGARYRDAHSGMSGPYAGLRRILQAVVHPHWAWNVGIMGRPHDLGNVSTYLQKKITLEDYVGWLGANFDPSIGWSDLQWIRDFWKGKMILKGILDPQDAREAVQFGADGIVVSNHGGRQLDGVLSTARALPAIAEVVTGDLTILADSGVRSGLDVVRMIAQGADAVMIGRAFIYALAAAGEKGVMHLLDLFANEMRVAMTLTGVRAVKEITHESLASTDALNQ
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL20_PSYCK
Sequence: MARVKRGVQANRRHKKILKRAKGYYGARSRVYRVAVQAVTKAGQYAYRDRRNKKRTFRRLWIARINAGARLNGLSYSRFINGMKKANIAIDRRVLADIAMHDAATFTALVEKAKAELA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: IF1A2_HALWD
Sequence: MSEESGRRNLRMPSDDEMFAVVVEHNGGNHVRVRCQDGENRMGRIPGRMKYRTWINEGDVVLVEPWAWQDEKANIEWRYSEQDAEQLRTEGHIK
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A 2, aIF-1A 2.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: ML2_VISAL
Sequence: MNARLASSRAWVWCFLMVGLVCGATAKAESKINYRRISLRVTDKTTGDEYFRFITILRDYVSIGSFSNDIPLLRQSTIPVSDAQRFVLVELTNQWGDSITAAIDVTNLYVVAYQAAGQSYYLRDAPHGAERHLFTGTTRSSLPFNGSYADLERYAGHRDRIPLGREPLLRSVSALHYPGGSTRAQASSIIIVIQMISEAARFNPILWRARQYINRGVSFLPDVYMLELETSWGRQSTQVQQSTDGVFNNPIRLGISTGNFVTLSNVRDVIPSLAIMVFVCRDRSSSSDVHNWPLVIRPVMVDDVTCTTSEPTVRIVGRNGMCLDVRDSDYRDGSRIQLWPCKSNSDPNQLWTIRRDGTIRSNGSCLTTYGYTAGSYIMMYDCNRAGWDLTTWQIRGNGIIFNPRSKMVIGTPSGSRGTRGTTFTLQTLDDSLGQSWLASNDTAPREVTIYGFRDLCMETSGGRVWVESCVSSKQNQRWALYGDGSIRPKPYQDQCLTSQGDSVRSVINLFSCTAGSPRQRWVFTNKGTILNLKNGLALDVRESNPSLRQIIIFSVSGNPNQMWLPVP
What is the function of this protein?
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.  The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity).
What are the official names of this protein?
Beta-galactoside-specific lectin 2, Beta-galactoside-specific lectin II, Beta-galactoside-specific lectin III.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: NAC_THEKO
Sequence: MMGMNPRQMKKLMKQLGIKMEELEGVEEVVLRMKGKEIILKEPAVTVMVVQGEKTYQIIPGSEEVREVLEISEDDIKLVMEQAGVDYDTAKKALEEAKGDLAEAILKLTEG
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: DDL_MARN8
Sequence: MSDLTHNDIQPYQAHPELVRALGRVAVFMGGDSAEREVSLKSGKAVLAALQSAGIDAVGRDIQGCLLRTVDEPDFDRVFIALHGRGGEDGTLQAILGQAGIPYTGSEVLASALAMDKLRTKYVFEGCGLPTPAFRAMTSVGEAEGIVAALGTPLSVKPAHEGSSIGIRKVNSAAELAEAYEAAARLDDLVLVEQWIEGPEFTVSLLQDKALPAIGLSTDHAFYDYDAKYLADDTRYRIPCGLAPDDELRLQHLALDAFRVLGCRTWGRVDIMQDRAGEFWLLEVNTVPGMTDHSLVPMAAKAAGISFEELVVRILRDTLAEGIDA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_PICAB
Sequence: MARSLKKNPFVANHSLRKIQNLNIKEEKKIIVTWSRASVIVPAMIGHTIAVHNGREHLPIYVTDRMVDHKLGEFAPTLLFQGHARNDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NU6C_SOLBU
Sequence: MDLSEPIHDFLLVFLGSGLILGGLGVVLLPNPIYSAFSLGLVLVCTSLFYILSNSYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYKDFHLWTVGNGITSMVCISLFISLITTISDTSWYGIIWTTRSNQIIEQDFLSNSQQIGIHLSTDFFLPFELISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL2_RICCK
Sequence: MALKNFNPITPSLRALVQVDKTSVWKGRPFKSLTKGISKTGGRNNHGRITSWHRGGGHKKLYRIIDFKRNKIDISAVVERIEYDPNRTAFIALIKYEDGQYSYILAPQKLSVGDKVISSQDADIKIGNCLPLKFIPIGTTVHNVEMKVGKGGQIARSAGTSVDLVGKDSGYAQIKLRSGEFRLIPLDCKATIGSISNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFPTKGKKTRKNKRTSKFIVKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SMG8_HUMAN
Sequence: MAGPVSLRDLLMGASAWMGSESPGGSPTEGGGSAAGGPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFRHQDPGDPGPGIRTEAGAVGEAGGAEDPGAAAGGSVRGSGAVAEGNRTEAGSQDYSLLQAYYSQESKVLYLLLTSICDNSQLLRACRALQSGEAGGGLSLPHAEAHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRNQDPAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPVGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHIDSSSSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAASKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNESSPAPPDSDADKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQVEVKTEKRPNFVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFIPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC).  Acts as a regulator of kinase activity.
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Amplified in breast cancer gene 2 protein, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: DCG1_YEAST
Sequence: METRILVVNPNSSKSMTVSLRETIEKTFSMESCKISYFTGPDTSPPQIDGQETSIKSMEACLPLLIDDQESVYYFQKFNGILIACFSDHPLVAKIKDRAAKEKADVSIVGLLDSSINYCNLVGKKFSIITSNKEWIPILNNSVESKFLTGNTVNKNLWKGTVSTDLQVLDLHSPENFQQIAEIIYRENIKKLDSDIVILGCAGFSGLQNKLAKTFQRDGTLFLDTIEIGLQILITMIRFVNSQK
What are the official names of this protein?
Protein DCG1.
What is the protein family that this protein belongs to?
Belongs to the HyuE racemase family.
Protein: PLH19_FORAG
Sequence: MNFKQNIVYKKMAISMKITAIRPIALVISFTLLSCKDKVKTVEQQDEPTKPNIVYILTDQWRGAALGYAGDPNVKTPHLDALAKEAVNFTNAVSVTPVCTPHRASLLTGKYPITTGMFLNDLYLPSEELCMAEIFKAEGYNTAYWGKWHLDGHRRSAYTPKERRQGFDYWKALECSHDYNKMPYYDNDNPEVKYWGKYSPFAIVEDANTYLEKQAKDDTPFLAVVSIATPHFPHGSAPQKYKDMYSPESLILNPNVSPKFEARSREELQGYYAHATATDEAIGLLLKQMDALGLNENTIVVFSSDHGEMMGANDVRPFQKQVAWDESIRVPFLIKYPGIDKQKGVTVNAPINTPDILPSLLGLSNIKIPDGIEGEDLSELIKNPDPEADREALVMNVAPFAGGYPNLPYRAIRTKQYTYARTTEGPSMFFDNVADPYQQNNLLGKPEFETLQNELDAKLNKKLAELGDEFKSRDYYLKKYNYVFGKNKPAIPYWEFNNGKGEVQSPIPVTQ
What is the function of this protein?
Sulfatase involved in ulvan degradation (PubMed:31285597).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
What are the official names of this protein?
Ulvan-active sulfatase, Polysaccharide utilization locus H protein P19, PUL H protein P19, Sulfatase family S1 subfamily 27 protein P19, P19_S1_27.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Periplasmic side.
Protein: RL7_YERPN
Sequence: MSTITKDQILEGVAALSVMEIVELISAMEEKFGVSAAAVAAGPAAAVEAAEEQTEFDVVLASFGENKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGVNKDEAETLKKSLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RPOZ_AGARV
Sequence: MIHPSYVELMKVVNNNVEIGEEPVVNSRYSIVIAAAKRARQIIDGAEPLIAHPKCNKPLSIAVEELYTGAVRIVSDDEDLNEGEEA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CLPX_BORA1
Sequence: MPEKKGSADAKVLHCSFCNKSQHEVRKLIAGPSVFICDECIDLCNDIIREEAQATARAAIRSELPTPVEIKSFLDQYVIGQTGPKRMLAVAVYNHYKRIRHGEIKGDEVELSKSNIMLIGPTGSGKTLLAQTLARMLNVPFVMADATTLTEAGYVGEDVENIIQKLLQNCNYDVEKAQRAIIYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQDFVQVDTTNILFIVGGAFDGLEKVIRDRTEKSGIGFSAAVRAKSERGVGELFGEAEPEDLIKFGLIPELVGRLPVVATLDELDEAALVQILTEPKNALIKQFQKLFAMESAELDIRPDALHAIARKALQRKTGARGLRSILESALLDTMYDLPTAGNIRRVVVDANVIEGDGKPLLIYADEVAGSDESAQGEVRDAAA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MSCL_PROA2
Sequence: MGFIQEFKDFAMRGNVVDLAVGIIIGGAFGKVVTALVDGVLMPPIGLLIGGVNFDQLAFELRAATAESAAVSLNYGAFLQTIVDFVIIAFSIFVVIKALNSLKRKSEEAPKAPPVPSKEEVLLGEIRDLLKERG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPAT_TRIEI
Sequence: MATINDNYLKLKAGYLFPEIARRVNTFAEAHPEAQIIKLGIGDVTEPLPKACIQAMTKAVAEMGDRSTFKGYGPEQGYAWLREKIAAQDFQGRGCDIDASEIFISDGSKCDSGNILDIIGNNNTIAVTDPVYPVYVDTNVMAGNTGAVNEKGEYEGLVYLPIRAENNFTAEIPTQKVDLIYLCFPNNPTGATATKEYLQTWVNYARANDAIILFDAAYEAFITDASLPHSIYEIEGAKECAIEFRSFSKNAGFTGTRCALTVVPKTLKGKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEEGKAQVKGLIQFYLENAKIICSQLQAAGLTVYGGVNAPYVWVQTPTGLSSWDFFDKLLQNCNVVGTPGSGFGAAGEGYFRISSFNSRENVNEAMKRITEKFKV
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: ATPA_CUPMC
Sequence: MQLNPSEISELIKSRISGLGADAEVRNTGTVISVTDGICRVHGLSGVMQGEMLEFPGNTYGLALNLERDSVGAVVLGEYEHISEGDTVKCTGRILEVPVGKELLGRVVNTLGQPIDGKGPINAKETDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDSIINQKGKGVFCVYVAIGQKASTISNVVRKLEEHGAMEYTIVVAATASDSAAMQYLAAYAGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEDYVAKFTNGAVTGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDDATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILPFEKGLHDHLKTKFADLVNRIEDTKDLSKEDEAALRAAIEDFRKSAAF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SHP1L_HUMAN
Sequence: MASGSKASVPADSFRTISPDRRGEKSASAVSGDTAAATTLKGTAIPVRSVVASPRPVKGKAGRETARLRLQRLPAAQAEDTGEAAAAAAEEPLLPVPEDEEEAQPLPPVCVSRMRGMWRDEKVSLYCDEVLQDCKAEDADEVMGKYLSEKLKLKDKWLGVWKTNPSVFFVKYEEASIPFVGILVEVTCEPYQDSSSRFKVTVSVAEPFSSNIANIPRDLVDEILEELEHSVPLLEVYPVEGQDTDIHVIALALEVVRFFYDFLWRDWDDEESCENYTALIEERINLWCDIQDGTIPGPIAQRFKKTLEKYKNKRVELIEYQSNIKEDPSAAEAVECWKKYYEIVMLCGLLKMWEDLRLRVHGPFFPRILRRRKGKREFGKTITHIVAKMMTTEMIKDLSSDTLLQQHGDLDLALDNCYSGDTVIIFPGEYQAANLALLTDDIIIKGVGKREEIMITSEPSRDSFVVSKADNVKLMHLSLIQQGTVDGIVVVESGHMTLENCILKCEGTGVCVLTGAALTITDSEITGAQGAGVELYPGSIAILERNEIHHCNNLRTSNSSKSTLGGVNMKVLPAPKLKMTNNHIYSNKGYGVSILQPMEQFFIVAEEALNKRASSGDKKDDKMLFKVMQNLNLEMNNNKIEANVKGDIRIVTS
What is the function of this protein?
Testis-specific spindle-associated factor that plays a role in spermatogenesis.  In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells.
What are the official names of this protein?
Testicular spindle-associated protein SHCBP1L, SHC SH2 domain-binding protein 1-like protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with alpha tubulin during meiosis. Colocalizes with HSPA2 at spindle during the meiosis process.
Protein: ARAT1_THELN
Sequence: MELEKRLKEKLEAPTLDYEKYFSEKALGMKASEIRELLKLVETSDVISLAGGLPAPETFPVEIIGEITKEVLEKHAAQALQYGTTKGFTPLRLALAEWMRERYDIPISKVDIMTTSGSQQALDLIGRVFINPGDIIVVEAPTYLAALQAFKYYEPEFVQIPLDDEGMNVDLLEEKLQELEKEGKKVKIVYTIPTFQNPAGVTMNEKRRKRLLELASQYDFIIVEDNPYGELRYSGEPVKPIKAWDEEGRVIYLGTFSKILAPGFRIGWIAAEPHFIRKLEIAKQSVDLCTNTFSQVIAWKYVEGGYLDKHIPKIIEFYKPRRDAMLKALEEFMPDGVKWTKPEGGMFVWATLPEGIDTKLMLEKAVAKGVAYVPGEAFFAHRDVKNTMRLNFTYVPEEKIREGIKRLAETIKEEMKK
What is the function of this protein?
Catalyzes the transamination of phenylalanine, tyrosine and tryptophan.  Shows virtually no activity towards aspartic acid, alanine, valine or isoleucine.
What are the official names of this protein?
Aromatic-amino-acid aminotransferase 1, ARAT-I, AROAT.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.