PharMolix/UniProtQA huggingface dataset:
Protein: SCD5_YEAST
Sequence: MSFDWLNVPGLDLSSGDQAEKRPSNGLGPPSVSFDFGINTAAPHDSSFWDQGSRSHSDTTLSYRNNHSNTAADNATNVSSPQKDNPPNGEVRTLSGGDVYAESPEDMQVPLSLSQNQLTHEEIRTYLRWYHYICLRTHGKLVRLNDVFRFLTNFNLSQKVKDRIVEIFRSCKNALNIGQFFAVLRLVSRAIIYGILPLRRMILEKAPVPKPRPILSSENHEEVYEEVEDDDSSAKTGDQKVDFDSFASLLLTGKTTRKRVRRRIKNLNFKSKKVRFSEHITFQDPPNLNQESSNNSEARKQDPDAEDEDQDSNNDSPLDFTLPMDQLLKRLYKRRKNSGLVSSLPSEQQETEEEKKVLEDMKDSLSHFKQIQTVDSASLPISSVFLQNGNTLPTSNVNNTTVPQQLPLEPLKPTATGSANHLVREEYNQGLHPSNGAIQTGLQPLKPTATGSANYLMRSHMEQPQSIKPSSTPETVTNSGGLQPLKPTATGSANYLMKQHISPSVNNPVSSMFQAQFTNQSSSPQSTGPAFLNSPNITLPQSNQQQPYQEVNPTQAKIEPSNISPQHTYSNNVRINNGNIVSMPKVEITGAFPPQNTLPQHQQSHLLSPQNTIPQHQRSQLISPQNTFTQNQPILSPQHTYSNNQATMISPQNTYTNNQQQPQHLPPPPPPRAQQQQQGAIVPPQHMYSNVQKQNNLVPTQPSYTNSPSIQSPNFLSPQNAANSYFQSLLSSSPSPNPTPSNASTVNGNNASNGISSFQNTSAAMNNTQSHQTYIQQQQQQQTQQRIYGGQLSQMQQHPGQLHLNNSDIHSQPNKPNYGMLGQQVHQQQQQQQQQFPFTADVNRSNSSDILGNLQSLQQQVDALQIQYNRRP
What is the function of this protein?
Regulates both fluid phase and receptor-mediated endocytosis (PubMed:12356757, PubMed:12956961).  Involved in vesicular transport at a late stage of the secretory pathway (PubMed:8688556).  Regulates actin cytoskeleton organization (PubMed:12356757, PubMed:12956961).
What are the official names of this protein?
Protein SCD5, Protein FTB1.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: MAC2_USTMA
Sequence: MQADKHAWKEVSPNLAQRPLVGVEKLLNYAEYYQNGNFQLSAAIHLETNLTTEKLQQRFGLAVWNVRCLLPEIGTWTVGTTGDAAVDLDNATFTAIQTVEEAQKWIDETAVIVQDGTTAEELTILTTNHTIEPAGKQFRVYLVTNARQGSPAIIVNASHVLSGHRIAAQLCTIVQALVDARLVSLLQAEPDPRAALRSIFVPENLARLIGKLPISLNTAYHKRFNPTEGDLENGFEKLSERLANSALPSIGIPRLSSPATNPEYSLGTVNGEAMTIMNLRRTIGSNEYRLLIDAHKKLGITVPSVIYACIVNSIDRRCKSNTAQDAETPGANLAYSAHAKRWLPDETFMTRSPVNMAIVLGSAYVSPDELRSKQHGCDLSIDELIELAKTIRAKQDAYLDTPHIISAMEQVGDEVSAMIADTAIKQRQAGTDPHVALFENSPAICPPTLTSQGDIAFKRLYTAQGGSWDPEPAVAAGEYVYIGHSWNSGRTTDASVCFALVGFSGELRLTSYFDSRFFDAKLIESILDDVLSNLRMIATTVPVDAPEAKL
What is the function of this protein?
Acyl-CoA-dependent acyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (PubMed:15932999, PubMed:16885300).  Mannosylerythritol lipid production is responsible for hemolytic activity of Ustilago maydis (PubMed:15932999).  Depending on the number of acetyl groups, mannosylerythritol lipids can be differentiated into MEL A (fully acetylated), MEL B and MEL C (monoacetylated at R-6 and R-4, respectively), and the fully deacetylated MEL D (PubMed:31103599).  The first step in the pathway is the generation of mannosylerythritol by the glycosyltransferase EMT1 which catalyzes the transfer of GDP-mannose to the C-4 atom of meso-erythritol (PubMed:15932999).  This reaction has to be stereospecific, since only mannosyl-D-erythritol is generated (PubMed:15932999).  The produced disaccharide is subsequently acylated with fatty acids of various lengths derived from the peroxisomal beta-oxidation by the peroxisomal acyltransferases MAC1 and MAC2 at positions C-2 and C-3, repectively (PubMed:16885300, PubMed:24835306, PubMed:31103599).  The existence of MEL derivatives which carry an acetyl group at C-2 implies that at least MAC1 also accepts acetyl-CoA as a donor (PubMed:15932999).  The final step of MEL biosynthesis is the acetylation of the fully acylated mannosylerythritol lipids catalyzed by the acetyl-CoA-dependent acetyltransferase MAT1 (PubMed:16885300).  MAT1 displays a relaxed regioselectivity and is able to transfer acetylgroups to both positions C-4 and C-6 of the mannosyl moiety (PubMed:15932999).
What are the official names of this protein?
Acyl-CoA-dependent acyltransferase MAC2, Mannosylerythritol lipids (MELs) biosynthesis cluster protein MAC2.
What is the protein family that this protein belongs to?
Belongs to the trichothecene O-acetyltransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: HEM1_GEOSM
Sequence: MNIIVVGLSHKTAAVEIREKVAFAPTQMEKPLQAVVALPDITEAVIVSTCNRVEIYATTRDVAGGMARIKRFLADYHNVPLELLEKHLYSYHGEDATRHVFRVASSLDSMVVGEPQILGQIKTSYGYAAEYKSSGIILNRFLHKAFSVAKRVRTETKIASSAVSVAFAAVELAKKIFGELSDKTVLLIGAGEMCELAAKHFINVGVRGVMVTNRTYERAEKLAEEFDAKPVHFEALMETLPKADIILSSTGAPHFIIHEKDMEDVLRRRKHKPMFFIDIAVPRDIDPKVNDVENCYLYTVDDLNGVVATNLEQRKVEAAKAEAIVEQEIGQFFKWLSSLEVTPTIVALRTHFDEIRKAELSKTVSGWKDLPPGAEKKLDALTNAIMNKLLHQPTSVLKRTDQGNRNDLYVDALRNLFDLEVGGETQDNMMDLED
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: H2B_CRYNB
Sequence: MAPKSVASKAPASQASKAPAAASKAPAKAAKTSAAPKDGAKKRSKKRVESYSSYIYKVLKQVHPDTGISNKAMAILNSFVSDIFERIATEASKLASYNHRSTISSREIQTSVRLILPGELSKHAISEGTKAVTKYSSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYGB_SHEPA
Sequence: MNFENLLIEIGTEELPPKSLRKLAESFLANFTEELTKAELSFESAVWHAAPRRLAICINQLALAQADKVVEKRGPAVAQAFDADGNPTKAAMGWARGNGITVEQAERLKTDKGEWLLHQARVVGVETKSLIADMAQRSLDKLPIPKPMRWGSNTTQFIRPVHTVTMLLGSEVVDGELLGIKSDRIIRGHRFMGESSFKLDHADNYLVALKEKGKVLADYEARKAIIKTDAEAAAAKIGGVADLEDDLLEEVTSLVEWPVVLTASFEEKFLDVPAEALVYTMKGDQKYFPVFDNAGQLLPNFIFVTNIESKDPQQIIAGNEKVVRPRLADAEFFFETDKKDTLEARLTSLETVVFQKQLGTIKQRVERISAMAGYIATSIDANSEEAARAGLLSKSDLMTNMVMEFTDLQGTMGMHYARLNGETEAVAVALSEQYKPKFSGDTVPTAPISICVALAEKLDTLVGIFGIGQAPKGAADPFALRRAAIGVLRICLENNLPLDLVDLIAKAQELHGENLTNADVAEQVLEFFMARFRAWYQDQGVSVDVILAVLARRPTAPADFESRIKAVAHFRTLEQASALAAANKRVSNILAKVEGELPAAIDDKLLVEAAEKALAEKLAELQPQLAPLFAAANYQEALALLASLRESVDTFFEDVMVMADDEALKNNRLALLSSLREQFLHAADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_META3
Sequence: MEYKFGEYGGQYVPEVLMPSLKELEKAYKKYKDDPEFKEELEYYLKQYAGRETPLYFAENLTKKMGGAKIYLKREDLLLGGAHKINNSLGQALLAKRIGKTRIIAETGAGEHGLSTAMVGALFGLKAKIYMGAVDVERQKLNVYKMRLHGAEVHAVQSGSKTLKDAINEALRDWVETFEDTHYIIGSAVGPYPFPSMVRDFQSVIGKEAKKQILEAEGRLPDSIVACVGGGSNSIGIFNEFKQDKEVKLIGVEAAGEGLDTDRHGAAILKGKKGVLHGMLSKFLQDDDGQIAETYSISAGLDYPGVGPEHAYLDEIKRVEYAGITDVEALDAFSTLSKTEGIIPALESSHAVAHGMKIAKEMDKDEIIIINLSGRGDKDIHTVMNFIEF
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RBSD_OCEIH
Sequence: MKKKGMLNSEISKVLSDLGHTDQIVIADAGLPVPEGVTKIDVALTPGTPSFLDVLKAVKADMVIEGVTLAREIKVDNTENHKQIQEVINDIPITYVTHEQFKALSKQAKAIIRTGEITPYANCILQSGVFF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTH_SALSV
Sequence: MSALCPLLTPPASEALLLAQARQLSGYTLGELAAMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_ACIBT
Sequence: MSDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASGRPHVRTVLLRGATEAGYDFYTNYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIPEQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQDLQQQVQSREVLDKPEFWGGYRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ARAA_BIFA0
Sequence: MAMENPFEGKEIWFGVGSQDLYGEEALRQVAQQSAEIVDSLNASGRIPVKLVLKPTLKSSDGVRRFMVDASADDSCIGVITWMHTFSPAKMWIRGLEALRKPLLQLNTQHHFEIPWETIDMDFMNLNQAAHGDREYGYIVTRLGIPRKIVVGHYTDPAVADKIGVWARACAGWQASNTMNVMRWGDNMRNVAVTEGDKTEAERVFGASINTWAVNELVAAYDAVKENQIKDLIEDYKAKYEIAPELLDKDYDSLFIAAREECAMVNMMRANGCTAGVDNFEDLGALPQLPGVGPQRFPSEYGWGFSAEGDWKTAVLVRIGAVMGYGLEGGASLMEDYSYNFTPGNEMIMGSHMLEVSPSVGTIAKPRLEIHPLGIGGKADPVRLVFTVAPKKDAVVVSLADVRTRFRMLMNVVDVVEPLGSLDKLPCARALWKPEPNLEISAECWLRAGGSHHTCMTTSVGREAWEDFARIAGVELAAIDAETTPREFERELEIEDVFHELANRH
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: RL27_CERS1
Sequence: MAHKKAGGSSRNGRDSAGRRLGVKLYGGQAAIPGNIIVRQRGTTWFPGAGVGMGRDHTIFATVEGRVEFRKGLKGRTFISVLPTAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SYM_ROSCS
Sequence: MPDTILVAVAWPYANGPFHVGHIAGAYLPADVFARYHRLRGHRTLMVSGSDCHGTPITIAAEREGITPQDVIRRYHPTFLKTFQALGISFDLFTQTYTDNHYRVTTDMFLRLLENGYLYKETMVGSYSETLGRFLPDRFVEGTCPNCGYPRARGDQCDSCGHLHDPQDLIAPRSVLDGAPVTFRETEHFFLDLAKLEPQLRAWIESVDRSYWRANTLLFTQNWLREGLRGRAITRDLEWGVPVPVDDPAFKDKRIYVWFDAVIGYYSASVEWAERTGAPDAWKDWWVCLPDGSAPARSYYFIGKDNIPFHTIIWPAMLIGYGNLALPYDVPANEFLNLEGDKMSTSRNWALWAPEIEDRYQPDAIRYYLIANGPETRDSNWSWADFVQRVNSELVATWGNLANRVLSITHRNFGAVPQPGELTDADRQLIAATQQTFESVTALLDGVKLRAALSEAMALAQTANQYLSEQEPWKLVRHDQERAATVLFVALRTVDTLKVLFCPFLPFSSQRLHELLGYTGTIAPQPHVEETTAPDGLPRLVLTGDYRASAGAWRISVLPPGQPIQPPTPLFQKLDEAIIAEELARLRAKVRL
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD2_VIBVU
Sequence: MATPHINAQPGDFAETVLMPGDPLRAKYIAETFLEDVKQVCDVRNMFGFTGTYKGKKVSVMGHGMGIPSACIYVHELIAEYGVKNVIRVGSCGAVRDDVNLMDVVIGMGASTDSKVNRIRFNDHDFAALADYGLLEEAVKQARAQNVPVKVGNVFSADLFYTPEADIFEKMEKLGILGVDMEAAGIYGVAADLKAKALTILTVSDHIIRGEKLSSEDRQKSFNDMMKVALETAINL
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 2, PNP 2.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: UXAC_BACP2
Sequence: MKAFLNEQFLLNSPTAEKLYHEFAKDLPIIDYHCHLSPKDIYENKTFRNITEAWLYGDHYKWRAMRANGIPETHVTGDASDYDKFLAWAKTVPMTIGNPLYHWTHLELRRYFEVQDLLNEKNADTIWQKVNEKLQEEGFGARDFIMKSNVETVVTTDDPIDSLQYHQKLREEGFSVQVLPGFRPDKALDIANDLFEKYVHELAEASAISIQSYQDFLNALRARIDFFHEHGCLISDHAINEMTYEETTQEEVETIFHKRMSGYPLTEKEKIKFKTETFIMLGQAYCERGWAMQLHINALRNNNTKMFERLGPDTGYDAMNDEDIAKPLCRILDRLEQEDALPNTILYSLNPRDNVVISTLAGSFQDGKTPGKMQHGTAWWFNDTKQGMTEQMMTLSSIGLISRFIGMLTDSRSFLSYTRHEYFRRLLCDIIGDWVEKGEVPYDLELLGEIVKGISYENAKQYFQFDRVKQLHHQSKIT
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: MNMA_CUPPJ
Sequence: MSGKRVVVGMSGGVDSSVTAWLLKQQGYEVIGLFMKNWEDDDDSEYCSTRQDWLDVVSVADLIGVDVEAVNFAAEYKDRVFADFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAETIATGHYARVRQNAAGRFELLKALDHTKDQSYFLHRLNQAQLSRTLFPLGEIPKTRVREIAAEIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKVVGEHIGLAFYTLGQRKGIGLGGSREGSGDAWYVARKDMASNTLYVVQGHDHPWLLTPTLVAADLSWVAGEPPLAGASMAAKTRYRQSDAPCVVDAADGDMLKLAFAEAQWAVTPGQSAVLYDGDVCLGGGIIQSAQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM5_PHANO
Sequence: MFAPPAARAMKVLDRSFFKKTIPTSAARIFNAKDISRCRKELTASRDTLPNNRVDPIRPDVDSERAQKGGKCLVLRPEVVHNDRTTWSPKLRDLEQDGTLGVIPFQLDLDYDFFTYSEITSAIIPPPETKQDDEIPQGFALAGHVAHLNLRERYWPYKYLIADVLADKNPMVKTVINKLDNVGTENAFRTFQYEVLHGPDDMNVELREQGCTFKFDFAKARQYATIMAGVGPFAIPAGKKKCFVWANDLNPESYKSLEDNIRINKVGDFVTPRNTDGADFIRQSAIDLLKSERSIPIYPKVKFSRSAPPTQKPVPDRTLVQPRTFQHYVMNLPASAITFLPSFIGLYSNIPGLSIGEAKKLFAPHTQQKLPMIHVHCFSTKSDDNVAETKEICAEISRQLQCEMTPETPDVNIHDVRDVAPKKRMFCASFRLPEEVAFREI
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: METN_LACLM
Sequence: MTAIIELNNLSVQFHQKGRLVTAVKNATLHIEKGDIYGVIGYSGAGKSTLVRTINLLQKPTEGQIVINGEKIFDSENPVKFTGAKLREFRQKIGMIFQHFNLLSEKTVFNNVAFALQHSQIEDKNGKKRYLTKKEKNDKVTELLKLVDLADLSDKYPAQLSGGQKQRVAIARALANDPEILISDEGTSALDPKTTNQILDLLKSLHEKLGITVVLITHEMQVVKEIANKVAVMQNGEIIEQNSLIDIFAQPKEALTKQFIETTSSVNRFIASLSKTELLAQLADDEELIHLDYSGSELEDPVVSDITKKFDVTTNIFYGNVELLQGQPFGSLVLTLKGSSEHRAAAKAYFVERHLKFEVLGKIERTVD
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COL12_MOUSE
Sequence: MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIVLLYILCALLTITVAILGYKVVEKMDNVTDGMETSHQTYDNKLTAVESDLKKLGDQAGKKALSTNSELSTFRSDILDLRQQLQEITEKTSKNKDTLEKLQANGDSLVDRQSQLKETLQNNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQSQMYSQSVVIMNLNNLNLTQVQQRNLISNLQQSVDDTSLAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLSSFTGQMDNITTISQANEQSLKDLQDLHKDTENRTAVKFSQLEERFQVFETDIVNIISNISYTAHHLRTLTSNLNDVRTTCTDTLTRHTDDLTSLNNTLVNIRLDSISLRMQQDMMRSKLDTEVANLSVVMEEMKLVDSKHGQLIKNFTILQGPPGPRGPKGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGTIGPVGPPGERGSKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKDGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAMEPLALQNEPTPASEVNGCPPHWKNFTDKCYYFSLEKEIFEDAKLFCEDKSSHLVFINSREEQQWIKKHTVGRESHWIGLTDSEQESEWKWLDGSPVDYKNWKAGQPDNWGSGHGPGEDCAGLIYAGQWNDFQCDEINNFICEKEREAVPSSIL
What is the function of this protein?
Scavenger receptor that displays several functions associated with host defense.  Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast.  Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR).  Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells (By similarity).  Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells (By similarity).
What are the official names of this protein?
Collectin-12, Collectin placenta protein 1, CL-P1, Scavenger receptor with C-type lectin.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Note=Forms clusters on the cell surface.
Protein: EFG_PARL1
Sequence: MARKTKLEDYRNIGIMAHIDAGKTTTTERILFYTGVSHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKDKRINIIDTPGHVDFTIEVERSLRVLDGAVTVFDSVAGVEPQSETVWRQADKYRVPRMCFVNKMDRMGANFYRCVDMIVTRLGAVPLVTQLPIGSEAEFEGLIDLLKMQEIVWKDESLGAEFEYRDIRPELKEQADEYHAKMVELAVEMDDAVMEAYLEGNEPDEATLKKLIRKGTISRKFVPVLCGSAFKNKGVQPMLDAVVDFLPSPLEVERMQGIDPKTEEPDTRGASDDEPLSVLAFKIMNDPFVGSLTFCRIYSGVMTTGTGVLNSTKDNRERIGRMLQMHANHREDIKEAYAGDIVAVAGLKNTTTGDTLCDPLKPIILERMEFPEPVIEVAVEPKTKADQEKMGIALNRLAQEDPSFRVSVDQESGQTVIKGMGELHLDILVDRMRREFKVDANVGAPQVAYRETLTKRAEIDYTHKKQTGGSGQFARVKIVFEPGEPGSGFQFESKIVGGSVPKEYIPGVQKGVESVKDSGPLAGFPMIDFKATLMDGAYHDVDSSVMAFEIASRAAFREGAQQAGVKLLEPIMKVEVVTPEEYMGDVIGDLNSRRGQISGTEQRGIAQVIHANVPLANMFGYVNTLRSMSQGRAQYTMQFDHYEQVPQAVSDEVRAKLA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1370_YERPY
Sequence: MQWLADYWWIILILLVGMILNGIKELRRLDHKRFLDNKPELPPHRDNNAQWDDEDDWPDQNKKK
What are the official names of this protein?
UPF0370 protein YPK_1370.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MTRB_METKA
Sequence: MAIVLIDPESQIAMDAVTGAVAEWSEDVVTLDVMPLYEKVEELEQYVNDMMRAMDPSTTTWGTLPGREGVHETAGFLTNFAHGFVIGTMIVALVAFTLAAVYKLHALRLLGL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit B, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B.
What is the protein family that this protein belongs to?
Belongs to the MtrB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CARA_BARHE
Sequence: MTQTIPSPKPWSINKPTALLVLANGTVIEGKGAGATGFAEAEICFNTAMTGYEEILTDPSYKKQIVNFTFPHIGNVGTNSEDIEDLIPLNCHGAVGAIFKADITHPSNYRANENLNQWLKKRKIIALCGIDTRALTVLIREKGALNGIIAHDPNGNFDINTLKKRAQKWTGLVNLDLAQEVTSKQSMKWNEKPWVWNKGYKTNNDASNFHIVAIDYGIKRNILRLIAAHSAHITIVPANTNIEEILAMNPDGVFLSNGPGDPAATANYAVPTIQALIDSNIPLFGICLGHQLLALAVGAKTIKMHQGHHGANHPVKDFITGKVEIVSMNHGFTVDTTSLPQHVEETHISLFDNSNCGLRIIGKPVFSVQHHPEASPGPQDSHYLFQRFFNLIMDYKKTA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: SPRY3_HUMAN
Sequence: MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEPEHEGRKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG
What are the official names of this protein?
SPRY domain-containing protein 3.
Protein: HIS3_BRADU
Sequence: MSAHSHEIEEGLSFQPRFDASGLVTCVATDVATGDVLMVAHMNDEALRKTIATGEAWYFSRSRNALWRKGETSGQTQRVVEMRTDCDQDAVWIRVEQIGAACHTGRRSCFYRKVEAEDGGAKLVFVDADRLFDPDAVYKK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ECO7I
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y591_CLOBH
Sequence: MLSYYAFIFFAKIMEVALMTIRTVLITRGEKLYGSIIGFIEVTIWLYVTSSVLSGIKDDPIRMVVYALGFTCGNYMGCVIEEKLAIGLLTINVITSESDGKRLAEILRDENVGVTMVDAEGKIEQKKMLIIHAKRKRREEIIRTIEGSDINAMISVNDIKTVYGGYGIRK
What are the official names of this protein?
UPF0316 protein CBO0591/CLC_0646.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BTUC_VIBVU
Sequence: MELHQLIAHKEKRWRATLLVMLAVLLVLSALYLMVGEVFLSPFSSLSSFEHKLLVDLRLPRLVAAMVIGAALAVSGATLQVLLGNVLAEPGVLGISGGASLAMVIALFLLPVMPTPTVFMLAAIIGALVFTLILVGMARAMHLSTSRMLLVGVALGILSGAFVTWAFYFSDDLSLRQLMYWLMGSIGGASWHHHLVTLVLLPVLVWLCLQGQTLDKLMLGETHAAQLGVDVHKVRWRLILAISILIGCAVALGGIISFVGLVVPHLLRMAFGSENRFLLPLSAFAGATLLVFSDIWARTLLDSAELPLGVMTTTIGAPIFIWMLIRSHDAH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL28_HAEIG
Sequence: MSRVCQVTGKRPAVGNNRSHAMNATRRRFLPNLHTHRFWVESENRFVTLRLTAKGMRIIDKKGIDAVLAEIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.