PharMolix/UniProtQA huggingface dataset:
Protein: AROC_CHLT2
Sequence: MHNQYGSIFSITTWGESHGPAIGVVIDGCPAGLSLSPEDFLPAMARRRPGQLHTSPRQEPDLVTILSGVYQNKTTGTPISLLIENKDVSSSSYEHLQHCYRPGHAQFAYEGKYGFADNRGGGRASARETASRVAAGVIAKKILLSQGIETLAFLSGFGTLESKNYPKLSDSLIQQVHTSPFYTLLPQEEIQNLLLLNPDDSFGGVVSFITSPLPIGLGEPVFGKLPALLAAGMMSIPAAKGFEIGAGFSSSQMTGSAYLDAFIADESGVSLQSNRCGGALGGISIGQPLEGRVAFKPTSSIKKPCSSVLKDGTPIAYRTPNQGRHDPCVAIRAVAVVEAMLDLTLVDLLLQHRCTQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DUSC_RALSO
Sequence: MSRLLLAPMEGVADFVMRDVLTSVGGYDGCVSEFVRVTGSLLPARTYERETPEIRNGGYTASGTPMVIQLLGSDPEWLARNAAQAATVSPHGIDLNFGCPAKVVNRHGGGAMLLATPELLHRIVSTVRAAVPARIAVTAKMRLGVSDTSLAIACATALAEGGAASLVVHARTRDHGYRPPAHWDWIARIADAVRVPVVANGEVWTVDDWARCRAVSGCDDVMIGRGAVSDPFLALRIRGQMARQPSDAEWPLVLGCLADYLKKLRARIAIHHEHGRVKLWLGYLKRTWPQAAELHDAIRRLQDSAEILGVIEHALARIGQQSAPAG
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: CTPC_MYCLE
Sequence: MTLAMAEQIATADNPAFVVVSDAAGRMRIQIEWVRSNPRRAVTVEEAIAKCNGVRVVHAYPRTGSVVVWYSPRCCDRQSILAAISGAAHVAAELIPTRAPHSSDIRNIEVLRMAIGAAALTLLGVRRYVFARPLLLPTTSRLVASGVTIFTGYPFLRGALRFGKTGTDALVSVATIASLILRENVVALAVLWLLNIGEYLQDLTLRRTRRAISALLSGTQDTAWIRLTDGPQAGTEIQVPIGTVQIGDEVVVHEHVAIPVDGEVIDGEAVVNQSAITGENLPVSVMAGSHVHAGSVVVRGRLMVRASAVGKHTTIGRIVTRVEEAQHDRAPIQTVGENFSRCFVPTSFVVSAITLAITKDVRRTMTVLLIACPCAVGLATPTAISAAIGNGARRGILIKGGSHLEQAGRVDAILFDKTGTLTVGRPVVTNIVAMHKDWSPEQVLAYAASSEIHSRHPLAEAVIRSTEERHISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLCAEKVKVSKTASEWVDKLRHQTETPLLFAVDGTLVGLISLRDEVRPEAAEVLTKLRASGVRRIVMLTGDHPDIAKAVATELGIDEWRAEVMPEDKLKVVRDLQNEGYVVGMVGDGVNDAPALAAADIGIAMGLAGTDVAVETADVALANDDLNRLLDVRDLGGRAVEVIRENYGMSIAVNAAGLFIGAGGALSPVLAAVLHNASSVAVVANSSRLIRYRLD
What is the function of this protein?
High affinity, slow turnover Mn(2+) transporting ATPase.
What are the official names of this protein?
Manganese-exporting P-type ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_SYNS3
Sequence: MTQQPYYETMYILRPDIPEEEVESHVTKYRDILTEAGAEVLDNQMRGKRRLAYPIAKHKEGIYVQLSHNGDGQQVGVIEKAMRLSEDVIRYLTVKQEGPLPAPRVAPGTEAPAEPEAAAPA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RLMH_NITOC
Sequence: MNIYVIAVGQRLPRWIGEGYQEYAQRLPRQCSLSLVEIAPARRGKSGHPTQWRQDECRRLLAAVPPNSKVIACDERGQSWSTEEVARRLQIWMNEGQDVVLLIGGPDGLAPLCLEQATGLWSLSSLTLPHGLVRVILAEQIYRAFSLLNRHPYHRAS
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_THEKO
Sequence: MNKREIARYIDQTNLKPYATKEDIIKLCDEAIEYGFYAVCVNPYRVKLAKDYLREKNADVKVASVIGFPLGATPTEVKVFEAKRALEDGADELDMVINIGALKDKDYEYVKNDIAEVVKVAHERGAKVKVIIETCYLTEEEKVKACELAKEAGADFVKTSTGFGTGGATVEDVRLMRKVVGPEMGVKAAGGIRTYEQALEMIEAGANRIGTSSGVKIVEGAPDE
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.  Could be involved in pentose biosynthesis.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_YERPP
Sequence: MSNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKEEVENLLYAGFLGVFIGGRVGYVLFYNLPMFLDNPLYLFKVWDGGMSFHGGLIGVICVMLWFARRTKRNFFQVADFIAPLIPFGLGAGRLGNFINAELWGRVTTDTPWAMLFPTSRNTDIAIVAADPAKWQAIFNQYGVLPRHPSQLYEMILEGVVLFIILNVFIRKPRPMGSVSGLFLIGYGTFRIIVECFRQPDEQLGLFEGMISMGQILSVPMILAGIIMMIWAYRRPTQKLS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRAC_CLOD6
Sequence: MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEENLDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAAIETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPGVGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLAHIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGEKFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFILK
What is the function of this protein?
Catalyzes the reversible interconversion of L- and D-proline.  Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways.  Strong B-cell mitogen.
What are the official names of this protein?
Proline racemase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: NOP10_METVS
Sequence: MQMKKCPKCGKYTLKEYCIDCNEKAGTVKPPRFSPVDKYGKYRRMLKKSLKK
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: GLD1_YEAST
Sequence: MDNFESTAEGNLSIGNKRVYELRKRNFQRNLVNNLSFLGYVLISLEYIKYDRTVWTLITRAIVQSLISSPFPSDAKLRRLATLGADNNTTGVATLPGGRSIRFPGMFGTEMLYNSSSEAEQQDHDDTAIVSMKKQIRKFLFHGCLSLNMLFIILTILFPIDFFEPLSGSEPVDDGPKNTPSPFSNSDGLLLGERRGGLFLQMIGERLPKSNFSGNLGLVMFEFSILIVQFTLFSLTCVVLADLDFEEPERLEPVNSDGYDGSVIVARIPLNKTMNAILNDGNINDNNENASNSV
What is the function of this protein?
Component of the Golgi/endosome-localized DSC E3 ubiquitin ligase complex involved in the targeting of the DSC complex to the Golgi apparatus and endosome membranes via the AP3 pathway to ubiquinate Golgi/endosome membrane proteins (PubMed:29355480).  Competes with VLD1 to determine the subcellular localizations of the DSC complex (PubMed:29355480).  May be required for cell cycle progression (PubMed:12829295).
What are the official names of this protein?
Golgi/endosome-localized DSC protein 1.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Protein: ODO2_STAAM
Sequence: MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVNVEVVSEEAGVLSEQLASEGDTVEVGQAIAIIGEGSGNASKENSNDNTPQQNEETNNKKEETTNNSVDKAEVNQANDDNQQRINATPSARRYARENGVNLAEVSPKTNDVVRKEDIDKKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEVDMTNVMELRKRKKEQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
What is the function of this protein?
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: G6PI_PROMT
Sequence: MNNNDKWARYCDLLYSDDSLGFWLDISRMDVAINDFEDFNEIYSKAFDALESLENGSIANIDEGRQVGHYWLRNPKVAPSPEISDSITKEIQDISKFGSSILNGEITNSDGEKYTDVFWIGIGGSGLGPLLIKESFKRESIGLDLHFLDNVDPEGISHKLNSILPNLNSTLFVVVSKSGGTPEPLIGMEQAMKFVRDNNQNWSSRAIAITSKGSKLDLLAHNENWLDIFDLPDWVGGRTSITGAVGLLPAALIGADINKFLNGASQMDALTRVKDIKNNPAALLSLAWFKSGNGKGLRDMVVLPYRDRLEVFSRYLQQLVMESLGKKFDRDENQVNQGIAVYGNKGSTDQHAYVQQLRDGIDNFFVNFIEILHDPLEIVEVKNKRPGDYLSGFLQGTRSALTEGGRQNLTITFKSFDESSLGALIALFERAVSLYAELINVNAYNQPGVEAGKKAATKIIKLQKEIEELLDDGKQRTLNEINDALSSDSTESIYLILRKLSENSDHYSMIGNQSNPDKLIISKT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_STRPC
Sequence: MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKDIKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTLLLDSVSFAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETDNVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSNQEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGALSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TM38B_XENTR
Sequence: MESFSELSLQFSQLSMFPFFETAHYLTSVMSAREQAGAVDVASRSPLASWFSSMLYCFGGGILSSILLAEPPVGILSNTTSIILASAVWYMVYYFPYDLFYNCFFFLPIRLILAGMKEVTRTWKILSGVAHAHSHYKDAMLVMITIGWARGAGGGLISNFEQLVRGVWKPESNEFLKMSYPVKVTLIGAVLFTLQHGQYLPISRHNLMFIYTLFLILIKVTMMLTRSTASPFLPLETSLQHILFSRQQIPAEVRESPSSSGDKGKPSKKTLDKDSGEQDNKKDN
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type B, TRIC-B, TRICB, Transmembrane protein 38B.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NU4LM_CYPCA
Sequence: MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALALWALQFESTGFSTAPMLLLAFSACEASTGLALLVATARTHGTDRLQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ZAPB_YERPA
Sequence: MSFEVFEKLEVKVQQAIDTITLLQMEIEELKEKNNTLTQEVQDAAGSREALVRENEQLKQEQHVWQDRLRALLGKMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: TULP2_HUMAN
Sequence: MSQDNDTLMRDILGHELAAMRLQKLEQQRRLFEKKQRQKRQELLMVQANPDASPWLWRSCLREERLLGDRGLGNPFLRKKVSEAHLPSGIHSALGTVSCGGDGRGERGLPTPRTEAVFRNLGLQSPFLSWLPDNSDAELEEVSVENGSVSPPPFKQSPRIRRKGWQAHQRPGTRAEGESDSQDMGDAHKSPNMGPNPGMDGDCVYENLAFQKEEDLEKKREASESTGTNSSAAHNEELSKALKGEGGTDSDHMRHEASLAIRSPCPGLEEDMEAYVLRPALPGTMMQCYLTRDKHGVDKGLFPLYYLYLETSDSLQRFLLAGRKRRRSKTSNYLISLDPTHLSRDGDNFVGKVRSNVFSTKFTIFDNGVNPDREHLTRNTARIRQELGAVCYEPNVLGYLGPRKMTVILPGTNSQNQRINVQPLNEQESLLSRYQRGDKQGLLLLHNKTPSWDKENGVYTLNFHGRVTRASVKNFQIVDPKHQEHLVLQFGRVGPDTFTMDFCFPFSPLQAFSICLSSFN
What are the official names of this protein?
Tubby-related protein 2, Cancer/testis antigen 65, CT65, Tubby-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Does not have a cleavable signal peptide and is secreted by a non- conventional pathway.
Protein: SPSA1_CRAPL
Sequence: MAGNDWINSYLEAILDVGPGIDEAKGSLLLRERGRFSPTRYFVEEVVSGFDETDLHRSWIRAQATRSPQERNTRLENMCWRIWNLARQKKQLENEEAQRMAKRRLERERGRREAVADMSEDLSEGEKGDIVVDHSHHGESNRGRLPRINSVDTMEAWMNQQKGKKLYIVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVSSPEVDWSYGEPTEMLPPRNSENMMDEMGESSGSYIVRIPFGPKDKYVAKELLWPHIPEFVDGALGHIIQMSKVLGEQIGNGHPIWPAAIHGHYADAGDSAALLSGALNVPMLFTGHSLGRDKLEQLLRQGRLSRDEINSTYKIMRRIEAEELSLDASEMVITSTRQEIEEQWRLYDGFDPILERKLRARIKRNVSCYGRFMPRMMVIPPGMEFHHIVPHDGDLDAEPEFNEDSKSPDPHIWTEIMRFFSNPRKPMILALARPDPKKNLTTLVKAFGECKPLRELANLTLIMGNRDNIDEMSGTNASVLLSILKMIDKYDLYGLVAYPKHHKQSDVPDIYRLAAKTKGVFINPAFIEPFGLTLIEAAAHGLPIVATKNGGPVDIHRVLDNGILVDPHNQESIADALLKLVAEKHLWAKCRANGLKNIHLFSWPEHCKSYLSKLASCKPRQPRWLRNEEDDDENSESDSPSDSLRDIQDISLNLKFSFDGDKNESREKGGGSHPDDRASKIENAVLEWSKGVAKGPQRSMSIEKGEHNSNAGKFPALRRRKIMFVIAVDCKPSAGLSESVRKVFAAVENERAEGSVGFILATSFNISEIRHFLVSEKLNPTDFDAFICNSGGDLYYSSHHSEDNPFVVDLYYHSQIEYRWGGEGLRKTLVRWAASITDKKGEKEEHVIIEDEETSADYCYSFKVQKPNVVPPVKEARKVMRIQALRCHVVYCQNGNKINVIPVLASRAQALRYLYLRWGMELSKTVVVVGESGDTDYEEMLGGVHKTVVLSGVCTTATNLLHANRSYPLADVVCFDDLNIFKTHNEECSSTDLRALLEEHGAFKA
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).
What are the official names of this protein?
Probable sucrose-phosphate synthase 1, UDP-glucose-fructose-phosphate glucosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: LGOR_ECOLI
Sequence: MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTTVRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQRQLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIHSEKRGQWSMKQFDQSYAEQLFELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHSLLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLDATLALRNHLNSAKQSMIRSINENTRYAH
What is the function of this protein?
May be a positive transcriptional regulator for lgoD and/or lgoT.  Is essential for growth on L-galactonate as the sole carbon source.
What are the official names of this protein?
Probable HTH-type transcriptional regulator LgoR.
Protein: RS5_SHIBS
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL9_ARTS2
Sequence: MAKLILTHEVTGLGAAGDVVEVKDGYARNFLLPRGFALTWSKGGEKQVESIKAARVAREHASLEDAQKQAAALSAKPVKLVVKAGETGRLFGTVKQGDVADAVEAAGLGRIDKRKVELPAHIKSVGSYQANVRLHDDVAAVIELDVVAGK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ERA_YERP3
Sequence: MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVEREGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: DPPA3_BOVIN
Sequence: MDSSEDNPTWTLESLKTSIDDASQAMQVATQLSEMLATNLSNLTLNPSIKLPYLPEYPSQLTGQLPSEKTPHRRRGVRTVLSERRYRMQKLIESLRLRYAKGIPRSDSQRQLQQQEDTEIRSRVRRFQCTCSYCQFKRNPSDDNYENYYNTTYSNYAMESNES
What is the function of this protein?
Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization.  In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process.  Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation.  Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark.  Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis.  May be important for the totipotent/pluripotent states continuing through preimplantation development.  Also involved in chromatin condensation in oocytogenesis.
What are the official names of this protein?
Developmental pluripotency-associated protein 3, Stella-related protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly localizes in the female pronucleus, localization to the male pronucleus in much weaker (By similarity). Expressed during blastocyst, morula and 4-cell embryo stages.
Protein: TR112_BOVIN
Sequence: MRLLTHNLLSSHVRGVGPRGFPLRLQATEVRINPVEFNPDFIVRMIPKVEWAALLEAADHLHLIQVPKEPIQGYEHNEEFLRKMHHVLLEVEVLEGTLQCPESGRVFPISRGIPNMLLSDEETET
What is the function of this protein?
Acts as an activator of both rRNA/tRNA and protein methyltransferases.  Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA.  The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor.  The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species.  Together with methyltransferase THUMPD3, catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates and at position 7 of tRNA(Trp) (By similarity).  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production.  Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.
What are the official names of this protein?
Multifunctional methyltransferase subunit TRM112-like protein, tRNA methyltransferase 112 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRM112 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Note=Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes.
Protein: AKR1_EMENI
Sequence: MSSGDPPSGLQASGSNSSAALGLSPPSAPSGKSAATPPKVATDDASVELSSMKSERSPAKSIPLGEDIMQVARIGEVSVMQKLFDEKKFTANYSDEEGITPLHWAAINNQYAMCKFLIDSGADVNAKGGESVATPAMWAAQRCHYYIVHLLLQYGADPLLTDVQGYNILHLATIDGNAFLLVLLLHQEIPVDVVDQQGHTGLMWAAYKGYPACVDLFLRWGANPNAVDDGGLAPLHWALVKGSLPCVLKILEYGADRFATTTDGKTPALVAQEMNTRHVWYRALSECGYDADGNRKVLPMGLGPYVRDKAIMSKFFFFWPFLLLFVVLWILSNMVVYFAIPVAAVAVFGLQWVAKKAASQGPSEFRIIQKTPFLAGVFAGSLFWVFVRYVLYVLPATYSTNPFLNLGFVVFFSLTTYFYFYSMVADPGYVPKLGSRNEQRAVIGQLFEEWKFDEENFCVYCMIRRPLRSKHCRRCSRCVAKHDHHCPWIDNCVGVNNLRQFVLYILCLEIGIILFLHLTFNYINGLPAPAEPICNILNDQICSFVLRDTFTLLLDVWIAIQLVWVTMLGVVQLVQVSRNQTTYENMRGHSLDRGHSSTRAFASAVTAGTTSLDAAGLSASGQGPNPALAQGGHRHRGGCLKQWSSLLGFDTFFATARDGLRDGPRAARPRNPFSRGIVTNCRDFWCDPAPYFGKREPGSAMLGGEIVNYNRMYETPSRMYSSGDYRSVAYDEAADIV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase akr1, Ankyrin repeat-containing protein akr1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RNC_THESQ
Sequence: MNESERKIVEEFQKKTGINFKNEELLFRALCHSSYANEQNQAGRKNVESNEKLEFLGDAVLELFVCEILYKKYPEAEVGDLARVKSAAASEEVLALVSRKMNLGKFLFLGKGEEKTGGRDRDSILADAFEALLAAIYLDQGYEKIKELFEQEFEFYIEKIMKGEMLFDYKTALQEIVQSEHKVPPEYVLVRTEKNDGDRIFVVEVRVDGKTIATGRGRTKKEAEKEAARIAYEKLLKERA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_SYNR3
Sequence: MAHKKGTGSTRNGRDSNAKRLGVKRYGGEKVTAGSILIRQRGTSVLPGVNVGQGKDDTLFALVDGVVNFETIRRATRERKRVCVTPL
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.