PharMolix/UniProtQA huggingface dataset:
Protein: OMT1B_MENPI
Sequence: MAPKEDSLALAEAWNHGFGFIKTSIVKTAVELGIPDILESRGAPVSIPELAAAVDCSADRLYRVMRFLAYHGIFKRTEPPPESTGGGSVYYAQTLVSRRLTRENLGPFVLLQGTMREPSGCVTAETLRMSKRPGLVDDNDSDRLYEDPVFSMKVFRDAMASHARMTTAAVIENYGEGFLGVGSLVDVGGSYGMALSMLVKAFPWLRGICFDLPEVVARASPLKGVEFVAGSMFESIPKADVVMLMFVLHNWSDEECVEILKRCKDAVPKNKGKVIIIDAVIDEDGNGDEFTGARLGLDVTMMANMFEGRERTYVEWAHIINEAGFRRHVVKNIKTLESVIEAYP
What is the function of this protein?
Flavonoid 7-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as pebrellin, aroma compounds which contribute to the flavor of peppermint, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:14697269).  Catalyzes S-adenosylmethionine-dependent regioselective 7-O-methylation of flavonoids; active on various hydroxylated flavonoid substrates, including luteolin (LUT), quercetin, kaempferol, isorhamnetin, apigenin (API), scutellarein (6-hydroxy-apigenin, 6-OH-API, SCU), 7,8,4'-trihydroxy-flavone and naringenin (NAR), and, with a lower efficiency, 7,8,3',4'-tetrahydroxy-flavone, taxifolin and hesperetin (PubMed:14697269).
What are the official names of this protein?
Flavonoid 7-O-methyltransferase 1B, MpOMT1B, 7,8,4'-trihydroxy-flavone 7-O-methyltransferase, Apigenin 7-O-methyltransferase, Isorhamnetin 7-O-methyltransferase, Kaempferol 7-O-methyltransferase, Luteolin 7-O-methyltransferase, Naringenin 7-O-methyltransferase, Quercetin 7-O-methyltransferase, Scutellarein 7-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: PNO1_ASHGO
Sequence: MVAPTALKKSGTDGQTAPGPTGSRIVGTDNTRSIEDDDDILIDQEDSGAAAAEQAEGAREQQGVVLDAEGKPRFAAAASVAETRVKAESRKVPVPPHRMTPLRNSWTKIYPPLVDHLKLQVRMNLKTKSVELRTHPRHTTDPGALQKGADFIKAFTLGFDLDDSISLLRLDDLYIETFEIKDVKTLHGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRLKERY
What is the function of this protein?
Required for small ribosomal subunit (SSU) synthesis.  Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: US20_HCMVA
Sequence: MRVISRARSACTWTSCTSLSPCSTSCPPSPAAPTLLRRRSLPQQRRRPSSSPNRRVRGVTTSPCPTRSLVYKRRVGAPQRLCAETVATMQAQEANALLLSRMEALEWFKKFTVWLRVYAIFIFQLAFSFGLGSVFWLGFPQNRNFCVENYSFFLTVLVPIVCMFITYTLGNEHPSNATVLFIYLLANSLTAAIFQMCSESRVLVGSYVMTLALFISFTGLAFLGGRDRRRWKCISCVYVVMLLSFLTLALLSDADWLQKIVVTLCAFSISFFLGILAYDSLMVIFFCPPNQCIRHAVCLYLDSMAIFLTLLLMLSGPRWISLSDGAPLDNGTLTAASTTGKS
What are the official names of this protein?
Transmembrane protein HWLF3.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NHAA3_SALTO
Sequence: MTGEIPRGRRWSARTTRASRLNSPLRAFLHTETGSARVLLAAAVVALAWVNLDESSYESLWGAVFSVRLGSWQVSHDLRFWVNSGLMTFFFLVIGLEVRRDFDLGELRERRRLMLPLLAGIGGILAPIAIYLAFNAGKPTAVGWGVVMATDTALALGMLAVLGPRFSDRLRNFLLTVAVVDDLIVIVVLAIAYPEHPSPMALFVAAGIFALVLLIRAAGVRWGPGYLLLGVAAWLAVSESGVDPVVVGLVMGLFTYAYVPARTELQRAADRFRLFREQPSPQLARSVRAGLASALSPNDRLQHIYHPWASYLIVPLFALANVGVVVDRELLARAATSPVTLGVLFAYVVGKPAGIVIASMLVPRLSHNQFRAPVGWAAIIGVGTVSGIGFTIALLIATHALHGPALDEAKVGILVATVGASLTTWLVFRLAARLAPARRARALLGASEGIIDLMVPVDPDRDHVRGPREAPVTVVEYADFECPYCGQAEPAVRELLVDYTSVRYVWRHLPLTDVHPYAQMAAEAAEAAAEQGAFWEMHDLLLAHQDELRPADLLRYAERLDLDLDRFREHLADRRGAGRIAQDVDAADLSSVSGTPTFFVNGRRHHGPYNIEALSAAVMSAFASARLRPEGGREPDHRSEAGSEQPDEEPGT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 3, Sodium/proton antiporter NhaA 3.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LUXO_VIBHA
Sequence: MVEDTASVAALYRSYLTPLGIDINIVGTGRDAIESLNHRIPDLILLDLRLPDMTGMDVLHAVKKSHPDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKATKLKNEADNPGNQNYQGFIGSSQTMQQVYRTIDSAASSKASIFITGESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAANDRQGAAELADGGTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRERGKDVIEIAYSLLGYMSHEEGKSFVRFAQDVIERFNSYEWPGNVRQLQNVLRNIVVLNNGKEITLDMLPPPLNQPVVRQSVAKFIEPDIMTVSDIMPLWMTEKMAIEQAIQACEGNIPRAAGYLDVSPSTIYRKLQAWNSKDEKQNV
What is the function of this protein?
Acts negatively to control the expression of luminescence.  At low cell density, LuxO is phosphorylated, and together with sigma-54, causes repression of the luxCDABEGH operon.  This repression could be indirect, LuxO could activate a negative regulator of luminescence.  At high cell density, LuxO is dephosphorylated and inactive, therefore the luxCDABEGH operon is not repressed and light is emitted.  LuxO and sigma-54 have also a role in activating the production of siderophore and in regulating the rugose colony morphology phenotype (By similarity).
What are the official names of this protein?
Luminescence regulatory protein LuxO.
Protein: Y1925_SERP5
Sequence: MIIYLHGFDSTSPGNHEKVLQLQFIDPDVRFISYSTLHPRHDMQHLLKEVDKAVQQGGDKHSLICGVGLGGFWAERIGFLCGIRQVIFNPNLSPEQHMQGKIDRPEEYRDIATKCVEDFREKNRDRCLVVLSRHDEVLDSQLSAELLHKYYEIVWDEQQTHKFKNLSPHLQRIKAFKTLP
What are the official names of this protein?
UPF0227 protein Spro_1925.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: CBID_CLOBK
Sequence: MLDLYVNCDGKKLRCGYTTGSCAAAAAKAAAIALFYNKKLKEINIDTPKGIELTIPIEKIVEDESFVECAVIKDGGDDVDITHGIEIWARAEKKSSGYTLKGGKGVGVVCGEGLYVPKGEPAINPVPRSMIEKEVRSVIPRDSGVEITIFVPKGEEIAKKTFNPRLNIIGGISILGTTGIVMPMSEDALKASIELEINQKTCHGEKELILLFGNMGEKMAKELNLKENNMVIMSNYVGFALNCCMARKLEKVTIVGHIGKISKIASGCFNTHSRICDTRLETLALELALMGYDKDLVTKIYNQKTTEGAVNLLGEGYEKLYKNLGKKIIRKIEQYTYDSIKADIVMYSMGRGILYSSIE
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: ILVD_BURM9
Sequence: MSYNRRSKNITQGVARSPNRSMYYALGYQKEDFDKPMIGIANGHSTITPCNAGLQRLSDAAVAAVKDAGANPQIFGTPTISDGMSMGTEGMKYSLVSREVIADCIETCVQGQWMDGVVVVGGCDKNMPGGMIALARINVPGIYVYGGTIRPGHWKGHDLTIVSSFEAVGEFTAGRMSQEDFEGVEKNACPTTGSCGGMYTANTMSSSFEALGMSLLYSSTMANPDQEKVDSAAESARVLVEAVKKDLKPRDIITKQSIENAVSVIMATGGSTNAVLHYLAIAHAAEIDWSIEDFERIRKRVPVICDLKPSGQYVATDLHAAGGIPQVMKLLLDAGLLHGDCMTITGRTLAEELKDVPSVPRADQKVIHPIDQALYKEGHLAILKGNLAEDGAVAKITGLKNPVITGPARVFDDEQSALAAILDDRIRAGDVVVLRYLGPQGGPGMPEMLAPTSAIIGKGLGESVGLITDGRFSGGTWGMVVGHVAPEAFVGGTIALVQEGDSITIDAHKLLLQLNVDDAELARRRAAWKQPAPRYTRGVLAKYAALARPANQGAVTG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: THIC_METVS
Sequence: MTQLTDAKSGIVTEEMKFVADEEKIDVNYLRKLIEKGYVVIPKNINRKTKPVGIGDNLRTKVNVNLGTSPDFIDISCELKKVEISNKYGADAIMDLSTGGNLPEIRSQIMKNTNLPIGTVPIYEVGVDSKEKYGRVIDMDEDLIFNVIERQAQEGVDFMTLHCGITKQSVDTLNKDPRKMGVVSRGGAFLTAYIMYHNKENPLYRDFDYLLEILKEHDVTLSLGDGMRPGCLQDNTDRAQIQELITLGELVDRCREKGVQVMVEGPGHVPYNNIQANMQIQKTICKNAPFYVLGPIVTDLAPGYDHITAAIGGTLAAVSGANFLCYVTPAEHVRLMKEEEVKEGLIASKIAAQAADVAKGNPVAWNKERQMADARIKHDWERQFEIALDSDKPKKMREEIPSKDEKACSVCGDYCALLMVEELGKR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: YM07_PARTE
Sequence: MLLLKNCLTIFFKNKNYVSWRFLEVNDRETWAEDYALDLDKYALEAYWLEAKEVKQDDASVLSCFVFKYQGWFFFFIYYYLFKTQAELDAEAKIDEELSDDEGNIDEDLEDFQNEAKVSTSLELF
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF7.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL32_NITSB
Sequence: MAVPKRRVSKTRAAKRRTHYKIKLVKPVKDKDGTWKLPHHVNPTTGEYK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LEGU_CANEN
Sequence: MVMMLVMLSLHGTAARLNRREWDSVIQLPTEPVDDEVGTRWAVLVAGSNGYGNYRHQADVCHAYQLLIKGGVKEENIVVFMYDDIAYNAMNPRPGVIINHPQGPDVYAGVPKDYTGEDVTPENLYAVILGDKSKVKGGSGKVINSNPEDRIFIFYSDHGGPGVLGMPNAPFVYAMDFIDVLKKKHASGGYKEMVIYIEACESGSIFEGIMPKDLNIYVTTASNAQENSFGTYCPGMNPPPPEEYVTCLGDLYSVSWMEDSETHNLKRETVQQQYQSVRKRTSNSNSYRFGSHVMQYGDTNITAEKLYLYHGFDPATVNFPPHNGNLEAKMEVVNQRDAELLFMWQMYQRSNHQPEKKTHILEQITETVKHRNHLDGSVELIGVLLYGPGKSSSVLHSVRAPGLPLVDDWTCLKSMVRVFETHCGSLTQYGMKHMRAFGNVCNSGVSKASMEEACKAACGGYDAGLLYPSNTGYSA
What is the function of this protein?
Asparaginyl endopeptidase able to cleave almost all peptide bonds on the carboxyl side of Asn residues, except at the NH2 terminus or second position or with N-glycosylated Asn (PubMed:8429028).  Responsible for the maturation (circular permutation) of concanavalin A from its precursor, by performing both cleavage and cleavage-coupled transpeptidation to form conA (PubMed:8429028, PubMed:34235541).
What are the official names of this protein?
Legumain, Asparaginyl endopeptidase 1, CeAEP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: URE1_HELPS
Sequence: MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKFMLRAAEEYSMNIGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNSETYHVFVDGKEVTSKPANKVSLAQLFSIF
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18A_RAT
Sequence: MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIAAGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L18a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXY_DEIRA
Sequence: MDSVTPTLPRNILSIQSWVSYGHVGNAAAIFPLQRLGFEVWGVHTVQFSNHTGYGAWTGPVFEPGVIAELLDGIEARGVLPQCDGVLSGYVGSGGTVAAVVGAVGRVRQAHPQALYCCDPVMGDVGRGVFVHPDLPALIAAQAIPAADIVTPNQFELELLTGQKVETLADALAAAHALRERLNPAGPRIVLLTSLVRADAPASSIETLAVTGEGSWLCRTPLLPLDPPRNGTGDAIAALFYGQFLRTGSAEQALTLSMSALYALLDLTHRLGTREIQLVAAQGEFERPRHLFAAERVE
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: ATPF2_BRUA4
Sequence: MDATFWALIGLIIFLAILAYLKVPGMVGRSLDERADRIKNELEEARTLREEAQQLLAEYHRKRKEAEKEAGDIVASAEREAKALLEDAKRATEEYVARRNKLAEQKIATAEVDAINAVRASAVDLAVAAAGKIVADKVDTKVAGNLFKDALSQVKSNLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TSAD_KLEP7
Sequence: MRVLGIETSCDETGIAIYDDQQGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTAKDIDAVAYTAGPGLVGALLVGATVGRALAFAWNVPAIPVHHMEGHLLAPMLEDNPPAFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTEGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFEDAVVDTLMIKCRRALEQTGFKRLVMAGGVSANRTLRAKLAEMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLQTGAKAELGVTVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP26B_HUMAN
Sequence: MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV
What is the function of this protein?
Has also a significant activity in oxidation of tazarotenic acid and may therefore metabolize that xenobiotic in vivo.
What are the official names of this protein?
Cytochrome P450 26B1, Cytochrome P450 26A2, Cytochrome P450 retinoic acid-inactivating 2, Cytochrome P450RAI-2, Retinoic acid-metabolizing cytochrome.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: AROK_PROMA
Sequence: MTYKLRPNQVIKKLGGRIIYLVGMMGSGKSTTGPHLAKLLKYSFIDQDELIEKVAKSSVSQIFREEGENGFRDIETQVLKQIGQRHSLVVATGGGLVTRSENWGVLHQGIVIWLDPNRELLFARLKSDKTVVRPLLDNKDPKDVLDSLIKQRYLSYAEADLHISIERETPEEVALVIFKKLSEIIRVQED
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPCH_ECOLC
Sequence: MENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGTQTLLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQMCVLVQIETREAMKNLPQILDVEGVDGVFIGPADLSADMGYAGNPQHPEVQAAIEQAIVQIRESGKAPGILIANEQLAKRYLELGALFVAVGVDTTLLARAAEALAARFGAQATAVKPGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: VATB_METM7
Sequence: MDAMQKTIEYTSVSRIAGPLMVIDGIEGIAYGEIVDITTPNGDKRTGQVLEAREEIAVVQVFEGTSELNTSETKVRFTGDTAKIGVSYDMLGRIFNGAGKPLDGGPEIIAEKKLDINGYPLNPVSRNPPNAFVQTGISTIDGTNTLVRGQKIPIFSGSGLPHNKLATQIARQAKVRGEGEQFAVVFAAMGITGEESNYFMDEFKKTGALEKAVVFINLADDPAIERILTPRIALTTAEYLAYEKGMHVLVILTDLTNYCEALREIAAARNEVPGRRGYPGYMYTDLACLYERAGRVKGREGTVTQIPILTMPDDDITHPIPDLTGYITEGQIVLSRELNRKGIYPPVDILPSLSRLAGNGQGEGKTRDDHSKVISQAYAAYAEGRGLRDLVAVVGEEALTERDRSFLKFADAFENSIVTQGVDEDRSIEETLDYVWDLLTILPREELKRVSDELIEKYLPKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SYT_CHLPN
Sequence: MIQVTCDQKNYEVLEGTTAAELAKQLKNSHQFIGVLINERPRDLSTHLNEGDTLVFLTSEDPEGREIFLHTSAHLLAQAVLRLWPDAIPTIGPVIDHGFYYDFANLSISESDFPLIEDTVKQIVDEKLAISRFTYGDKQQALAQFPQNPFKTELIRELPENEEISAYSQGEFFDLCRGPHLPSTAHVKAFKVLRTSAAYWRGDPSRESLVRIYGTSFPTSKELRAHLEQIEEAKKRDHRVLGAKLDLFSQQESSPGMPFFHPRGMIVWDALIRYWKQLHTAAGYKEILTPQLMNRQLWEVSGHWDNYKANMYTLQIDDEDYAIKPMNCPGCMLYYKTRLHSYKEFPLRVAEVGHVHRQEASGALSGLMRVRAFHQDDAHVFLTPEQVEEETLNILQLVSTLYGTFGLEYHLELSTRPEKDTIGDDSLWELATDALNRALVQSGTPFIVRPGEGAFYGPKIDIHVKDAIQRTWQCGTIQLDMFLPERFELEYTTAQGTKSVPVMLHRALFGSIERFLGILIENFKGRFPLWLSPEQVRIITVADRHIPRAKELEEAWKRLGLVVTLDDSSESVSKKIRNAQNMQVNYMITLGDHEINENVLAVRTRDNRVINDVSVERFLNTILEEKNSLSLTALL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_SALTI
Sequence: MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLVLGISGGQDSTLAGKLSQMAITELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGTDHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLDSAIAKTIEGWYVKTEHKRRLPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: MUTL_DESRM
Sequence: MSNITILDEATANKIAAGEVVERPVSVVKELVENSLDAGANRISVELTQGGITGIKVVDNGYGMPAEDVQLCFLRHATSKIKRAEDLNSILTLGFRGEALPSIAAVSKVTLTTRTEDELAGTTMQIEGGYMQNVVPTGCPVGTIIEIKDLFFNTPARRKFLKTANAETSQVSDLITRLAMARPDVRFELRSGNRVLFSSPGTGSLKDTAAVIFGLDNVRSMLEIGYQGKLLSVAGLISKPVLTRASRHYQNFFINGRYIRSGFLSSILQQAYDTLIPAGRFPIAILHIDIDPTQVDVNVHPTKMEIRMAREGEIQEELLAALSDSLNVPTAITGLWEIMPGRTKNTATDQRAENLEVKPDSKEKELQPKESQHPRLVACDLPSGKIMPPRHDQEQLHFSSRRIAPVRGKNSLLPDEGSSINREEIPPVVDVKEQQLKENPNTYQPAETLGFPVLVPAGQVPPTYVLAHGEGGLYIIDQHAAHERVLYEKYLYLLGNYVEAQMLLEPLTLEIPHHEAQLIIKHIVDFNELGFILEHFGGDTFLLRGVPTNAITEPKEVFLDLLARLQENPSQKVEKNLVLDHLAAAMACRDAVKSGQHFSAVETKALLDGLARCQKPYTCPHGRPTLIQISQEELKKRFKR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PGK_LEGPC
Sequence: MNLIKMSDIDLSGKRVLIREDLNVPIKDGMITSDQRLQAALPTIKSALDSGAAVIVLSHLGRPEEGKYEKKFSLEPVADYLRENLEYPVRFVKDYLTGVDVNPGELVVCENVRFNPGEKGNDEALAKKLASLCDVFVMDAFGTAHRAQASTYGVAQYAPVAVAGPLLIRELEALNQVLKAPKKPIVAIVGGAKVSSKLSLLKQLVGMVDVLIPGGGIANTFLKAQGFEIGISLYEPDLLDEARHILILAKEKGCQIPLPTDVVVGKTFSETCPAFNKSLSNVAADDMILDIGPETIRDYVDLIHEANTIIWNGPVGVFEFPQFAYGTRAIAIAIAESDAFSIAGGGDTLAAVDLYDLNQQISYISTGGGAFLECLEGKTLPAVAILQERAKHVKTN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_CHLTE
Sequence: MQAKAILRHTPTSPRKMRLVAGLVRGKRVDQAKAILHNSTKSASRNVMVTLKSAVANWSQLNPDERLNDNELFVKAIFVDEGPSLKRLLPAPMGRAYRIRKRSNHLTIVVDKVENKVTK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YFBV_SHIF8
Sequence: MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGLLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_ECO57
Sequence: MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.