PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_CLOPS
Sequence: MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEFARIKEAAKKIQSDSDVLVVIGIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNNISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILKDYMEKKYGKEEAKKRIYATTDAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREEYANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGLFPAAVDFSTDLHSMGQYIQEGRRDIFETVINVGSPREEIVIEVNDENIDGLNFLAGKTMDYVNKQAFRGTLLAHNDGEVPNLVVNVPELTPYYFGRLVYFFEKACGISGYVLGINPFDQPGVEAYKKNMFALLGKPGFEDLKAELEERLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SST_XANC5
Sequence: MTEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAAANQANPEPGWWEAMLGPGKPIDTARWFVVCVNSLGSCKGSTGPASVNPATGAPYRLSFPDLSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDARYPESGMRMARKLGVITYRSALEWDGRFGRVRLDSEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEHVDEQPATDSAIDHAHADALPASAKPQTGVSTADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGGADAHFIGLDSPQGHDAFLVDFARFGPAVRDFLQDC
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_DROMA
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YD213_YEAST
Sequence: MPVRSLSASNSKNAIPLSALRRIWSGELFLKWFCNSTAVMSLGKLPTKTINLLPFLPFLPLPPRPLRVFLFFFTGSSPSFPAALLGLFPSGACSFFTSFS
What are the official names of this protein?
Putative uncharacterized protein YDL213W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: 3BHST_VAR67
Sequence: MTVYAVTGGAEFLGRYIVKLLISADDVQEIRVINVVEDPQPLVSKVKVINYIQCDINDLIR
What are the official names of this protein?
Truncated 3-beta hydroxy-5-ene steroid dehydrogenase homolog.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
Protein: PPK4_PRAMA
Sequence: AELPQGLWVRPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-4, PK-4.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLSA_PSYCK
Sequence: MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQSISKVFTLTIGLGKLGDAIWTHVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDAIMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDHRDRNAALAHFMKSFGHIKHDVDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHYDGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTGWSVFSN
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: HSLV_STAA1
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_SHIDS
Sequence: MSKNYHIAALPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGIRTRDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL21R_MOUSE
Sequence: MPRGPVAALLLLILHGAWSCLDLTCYTDYLWTITCVLETRSPNPSILSLTWQDEYEELQDQETFCSLHRSGHNTTHIWYTCHMRLSQFLSDEVFIVNVTDQSGNNSQECGSFVLAESIKPAPPLNVTVAFSGRYDISWDSAYDEPSNYVLRGKLQYELQYRNLRDPYAVRPVTKLISVDSRNVSLLPEEFHKDSSYQLQVRAAPQPGTSFRGTWSEWSDPVIFQTQAGEPEAGWDPHMLLLLAVLIIVLVFMGLKIHLPWRLWKKIWAPVPTPESFFQPLYREHSGNFKKWVNTPFTASSIELVPQSSTTTSALHLSLYPAKEKKFPGLPGLEEQLECDGMSEPGHWCIIPLAAGQAVSAYSEERDRPYGLVSIDTVTVGDAEGLCVWPCSCEDDGYPAMNLDAGRESGPNSEDLLLVTDPAFLSCGCVSGSGLRLGGSPGSLLDRLRLSFAKEGDWTADPTWRTGSPGGGSESEAGSPPGLDMDTFDSGFAGSDCGSPVETDEGPPRSYLRQWVVRTPPPVDSGAQSS
What is the function of this protein?
This is a receptor for interleukin-21.
What are the official names of this protein?
Interleukin-21 receptor, IL-21 receptor, IL-21R, Lymphocyte receptor beta, LR-beta, Novel cytokine receptor 8, NR8, Novel interleukin receptor.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y597_BUCCC
Sequence: MAGHSKWANTKHRKSAQDIKKSKIFTKITRKITISCLKNGTDVNKNFQLRRILEKANLYNLKKDLIQKAINRGKDKNKNIQKKSFNMKYAGYGPSGIVIIIFCNTDNSNRTISNIRNIFSKFKGKLVKYNDIKYLFNFFYYININNIVNNKEIVLSIIKKNNIKNFKQIDKNNMEIIIKLNKFKKIKKIFLSSSIVFTNVNLVIKPKNIYIINNIYKSKIKNMINLLKKLKETTKIIHNTKI
What are the official names of this protein?
Probable transcriptional regulatory protein BCc_197.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WN10B_PLEJO
Sequence: SGSCQFKTCWHVTPEFRLVSSVLKEKFQRATFINSHNKNTGVFHPRRLKKKRLAKELVYFEKSPDFCERDTKVDSPGTQGRVCNKTSHQMDSCGNLCCGRGHNILMQTPSERCNCRF
What is the function of this protein?
Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade.  Involved in neurogenesis.  Performs a partially redundant function with wnt1 in the formation of the midbrain-hindbrain boundary (MHB) organizer.
What are the official names of this protein?
Protein Wnt-10b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: LIAS_DROME
Sequence: MLRALKTHAEAPIVVATRAASTNAEKLEEIRERLAKGPNFHDFVQNPDNTRNEWEQYDGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARKPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSEHIAETVREIKARNSNIFVECLVPDFRGNLECVKTIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDEEIENTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNELGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNDTEVPKKQ
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOB_DESPS
Sequence: MERVRKNFATADNVLEPPHLISMQRISYEEFLQIDRAPEEREDVGLQAILKNIFPINDFNGLCSLEFLKYKFGEPKYTVQECQQRGMSYEIPLKIVVRLITFDVDEETGVQTIRDMKEQEVFLGSLPLMTADGVFVVNGTERVIVSQLQRSPGLFYSHDNGKSHSSGKLLYSARIIPVRGSWIDLEFDIKDVLHVRIDRRRKFPVTTLLKALGYSSEELLREFYPLENVKLSDGKYWVRFVAEHTAGQRLEFDLVNPQDGEILAKKGRKISKALCRKAVEAGIEFIEASSETILGKVLASAITLAGAEEPLYPCNTEITETVLENLAENGINEFETLFMDGVNYSASFSHTLRLDKVITTAEALLEIYRRLRPSSPPTLEIATTFFENLFFNPDLYDLSEVGRYKINAKLGLKTDIEHRALTRDDIIYGVRYLVRLKDNQGGIDDIDHLGNRRVRTVGELVENQYRMGLVRMERAIKERMTLQDVETLMPHDLINPKPISAAIKEFFGTSQLSQFMDQTNALSEVTHKRRLSALGPGGLSRERAGFEVRDVHPTHYGRICPIETPEGPNIGLIVSLATYARVNPYGFIETPYRKVENRVILDDIRYLSALEEQKQIIAPALVALEADHQSISEGNLIAREEGDVITIGSDNVTYMDVAPNQMISVAASLVPFLENDDANRALMGSNMQRQAVPLLVTAAPLVGTGMERYVARDSGACLLSAGDGVVEEVDSNRVVVRYDKPGVDGYDTGVAVYRLTKYKKSNQNTCFTQTPTILPGLKVEKGTLLADGPGCEAGELALGKNLTVAFMPWRGFNYEDSILINERLLKEDAYTSIHIDVFETMARDTKLGKEEITRDIPNVSEDTLRNLDDSGIVRVGAEIKPGDTLVGKVTPKGETVLSPEEKLLRAIFGEKAQDVKDSSLRVPPGVTGVVIDAKVFSRKGVDKDERSLMIEDLEIERLEGDKRDELRSLKNGVCRELGELIAGNTALGDILDSKGELLISSGDKIEVVHAIAIGFHRLKDIDFSGMADCTDRMDAAYERYQKQAEVIAQRYDGIIERQKKGDDLPPGVVKMVKVYVATKRKLSVGDKMAGRHGNKGVVSRILPEEDMPYFANGDTVDIVLNPLGVPSRMNVGQILEVHLGFAAKNLGAQLEKLAEQYAVEEIKAKLSRVYSDSEYHAIIDGKTDAEVIDWAYRHRKGLHMATPVFDGAEEAEIRKLLIESGVDKGGQSQLYDGLTGEPFANLVTVGVMYMLKLHHLVDNKIHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYTLKEFLTVKSDDVEGRTTMYERIVKGNNFLTTGLPESFHVLVKELQGLCLNMELIEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TMUUS_STRCL
Sequence: MSLNHSDLMFYCPVDDLPHPAASGVNDRTLDWASGQGIPTADRDAGRLRAMAPGLLAARIAPDARGPVLDAFADHHTWLFAFDDEYCDRADGSGITEWASFLARLHRVVETGESALLPGNPYGLALRDIACRLSTYTTPAQLAEWLEALRSYFAALVWERSRRRDDDRLQSLDDYLLLRLRNGAMHTSITLLDTVNGYVLPRELRETPGVRALVEMTALLVSVDNDILSHHKESTSGTREANLLDVLGRTGHTTPGEAVAQAVALRNEIMRQFVRVAERVRTPAAVPELYRFTTGLARWIRANLDFSLTTTRYTGPVTERAALSPHEVPPLSGQGPAPARSDVIGWWWRIPEPLPEPGSDGADTPVRKRRAGDRPPTAGRGGAPHHQRTGPPPPVLPGGITASRSSGLQQSTWRREHR
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (+)-T-muurolol via a 1,10-cyclization, which requires isomerization of FPP to nerolidyl diphosphate (NPP) and then abstraction of the pyrophosphate from intermediate NPP leading to a (E,Z)-germacradienyl (helminthogermacradienyl) cation.
What are the official names of this protein?
(+)-T-muurolol synthase ((2E,6E)-farnesyl diphosphate cyclizing), Terpene cyclase, Type I terpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: YP063_YEAST
Sequence: MTLNNVARPDLCVSYKKIAPPKGLYSATPSISGVVNQSMPMAAIFLRNKFIAWFSLIQSVHYYLNTDEDIIVAYKENKAPSPMDQPPAIKLFMSLIGLCVCYMNLVFPQQIAQPSSSGSKGNTETTIETTTEVETETAKQ
What are the official names of this protein?
Uncharacterized protein YPR063C.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RR2_ORYSI
Sequence: MTRRYWNINLKEMIEAGVHFGHGIKKWNPKMAPYISAKRKGTHITNLARTTRFLSEACDLVFDAASQGKSFLIVGTKKRAADLVASAAIRARCHYVNKKWFSGMLTNWSITKTRLSQFRDLRAEEKMEKFHHLPKRDVAILKRKLSTLQRYLGGIKYMTRLPDIVIVLDQQKEYIALRECAILGIPTISLADTNCDPDLANISIPANDDTMTSIRLILNKLVFAICEGRSLYIRNH
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NOG1_ARATH
Sequence: MVQYNFKRITVVPNGKEFVDIILSRTQRQTPTVVHKGYKINRLRQFYMRKVKYTQTNFHAKLSAIIDEFPRLEQIHPFYGDLLHVLYNKDHYKLALGQVNTARNLISKISKDYVKLLKYGDSLYRCKCLKVAALGRMCTVLKRITPSLAYLEQIRQHMARLPSIDPNTRTVLICGYPNVGKSSFMNKVTRADVDVQPYAFTTKSLFVGHTDYKYLRYQVIDTPGILDRPFEDRNIIEMCSITALAHLRAAVLFFLDISGSCGYTIAQQAALFHSIKSLFMNKPLVIVCNKTDLMPMENISEEDRKLIEEMKSEAMKTAMGASEEQVLLKMSTLTDEGVMSVKNAACERLLDQRVEAKMKSKKINDHLNRFHVAIPKPRDSIERLPCIPQVVLEAKAKEAAAMEKRKTEKDLEEENGGAGVYSASLKKNYILQHDEWKEDIMPEILDGHNVADFIDPDILQRLAELEREEGIREAGVEEADMEMDIEKLSDEQLKQLSEIRKKKAILIKNHRLKKTVAQNRSTVPRKFDKDKKYTTKRMGRELSAMGLDPSSAMDRARSKSRGRKRDRSEDAGNDAMDVDDEQQSNKKQRVRSKSRAMSISRSQSRPPAHEVVPGEGFKDSTQKLSAIKISNKSHKKRDKNARRGEADRVIPTLRPKHLFSGKRGKGKTDRR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LEPA_STRP3
Sequence: MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTARDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVCHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VMPAR_HIPPR
Sequence: AYDPDPYKRYSAEHTFFLL
What is the function of this protein?
Zinc metalloproteinase that causes hemorrhage in mice following intradermal injection and impairs hemostasis in its prey.  In skin tissues, it degrades components of the basement membrane surrounding blood vessels and capillaries.  In muscle tissue, it degrades the extracellular matrix, thus causing muscle necrosis.  However, it lacks direct toxicity on myocytes.  Hydrolyzes alpha-2 chain (COL4A2) of type IV collagen more slowly than the alpha-1 chain (COL4A1).  Hydrolyzes fibronectin (FN1).  It also impairs hemostasis by acting on fibrin(ogen) and platelets.  Shows fibrinolytic activity, with a selective degradation of gamma-dimer (FGG).  Shows fibrinogenolytic activity by preferentially cleaving the Bbeta chain, and later gamma-chain.  Aalpha-chain remains resistant to proteolytic digestion.  Weakly inhibits collagen-triggered platelet aggregation of human plasma rich platelet.
What are the official names of this protein?
Zinc metalloproteinase partitagin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAIB_SYNS3
Sequence: MSPRKTYILKLYVAGNTPNSMRALKTLRNILETEFKGVYALKVIDVLKNPQLAEEDKILATPTLSKILPPPVRRIIGDLSDRERVLIGLDLLYDELVDNDLNSSLMDALGVPDIEEADS
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: EX7L_LISMC
Sequence: MEQDKYLTVAAITKYIEKKFEVDPYMKQVFVRGEISNLKQPASGHLYFTVKDEFAMLRSVMFHKAVQKIGFVPEDGMNVLITGRIGVFTKAGRYQFYAEHMEPDGVGALYIQLEQLKSQLEKEGLFAETHKKVLPSFPSKVAVVTSKTGAAVRDILTTIHRRMPSVEVIVYPTIVQGEKAAQKIVENIGKINQRNDIDVMIIGRGGGSLEELWAFNEEPVVRAVYDSDVPVISAVGHETDFALSDFSADVRAATPTAAAELAVPDYRDLEERLAERKYRLLAVTRQALERKERSLEQLKQHLILNGPKHQLEQQMERTDYFSERLNNAFSKQIFVKQTVFDRLNDRLHYYHPNKEIELQKEQMALRLQALEKAMKQLLKDKQQSFFRQIDALEHLSPLSLLKRGFGVTYKENMLVKSVQELEVGDNIQVKMQGGQIEALITAKEEDISGN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSB_ECO81
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGRISNDIISIDYTDFVRLTVKHSSQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_POLNA
Sequence: MKVNAKSDHKLLPKVTKVVAKGDAKGKKVNKAWLHDHINDPYVKQARKEGYRARAAFKLKEMDETLGLIKPGDCVVDLGSTPGAWSQYVRRKLSPTGAAVGALNGRIIGLDLLPMEPIEGVVFIQGDFREPEVLAKLEQALSTEKGPVKVDLVISDMAPNLSGIESADAARIAHLVELAVEFAQTRMKPDGALVVKLFHGSGYDDLVKLFQASFKVVKRMKPKASRPNSSETFLVGRGLKNVTPV
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_BORBU
Sequence: MKKILAEIAYDGSIYHGFQIQPTKPTVQGEIEKALMKINKKKVKIHSSGRTDKGVHAKKQIITFDIKINIQLNNLKKALNAILLKNSIKILKLRYVKNSFHPRFSAQKRKYSYCILNSDNYYPWEGYQAHYVNKKLSISNLNQMAKTLIGKHDFTTFSCIKDKSKSKFRHIYFAKFKKRGKYIIFEIIGSSFLWKMVRSIIGTMLDIEIKNESISTFETILKSKNRNLARTTAPANALFLERVYYE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GCH1L_STAAM
Sequence: MKIADLMTLLDHHVPFSTAESWDNVGLLIGDGDVEVTGVLTALDCTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQHDINLIAMHTNLDVNPYGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDKLSENGLAQEGNYEYCFFESEGRGQFKPVGEANPTIGQIDKIEDVDEVKIEFMIDAYQKSRAEQLIKQYHPYETPVFDFIEIKQTSLYGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGESNQKIKRIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYSEYVMKEGLKTLLMNWFNIEKINIDVEASTINTDPFQYI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: GSFR2_PENAE
Sequence: MPPLYRRSCITCVQSKRKCDQGLPKCQRCLAKNIHCEYNPRYPNRRRQTTERNVDENVSLVEPIAEEPSRGCQLQRSPARPTSPTHSPHANDIFFNFANDPFNLESIPQDNFLNSTIFEDVVTQQAPNDTERITSDTTAQARVEFAAKKLSVIPKIFSQQGQTMFIHRQLFQDRAPPALQDALSACALYCLKSTENQTLVFRNLEHKRKQLISSIDPLLASKLDLLEALQALVLYQIISLFDGDIRLRAQAEADEPVLLMWAAQLTLRTPQFQPPLGLSNPQSLAGSASMDWGRWLIEESSRRTLITASMLKGVYSFVKLGYDTVPDMRMSFTAQAVLWNSQSEISWRRAYKEKERLEIQVTHWDETIAKAKANDLEELGVLIMVMLKGTGATGEWLGHSQNIRYGLEEAYYGSV
What is the function of this protein?
Transcription factor that regulates expression of the gene cluster that mediates the biosynthesis of Griseofulvin, an important antifungal drug that has been in use for a long time for treating dermatophyte infections (PubMed:20534346).
What are the official names of this protein?
Transcription factor gsfR2, Griseofulvin synthesis protein R2A.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_BRUC2
Sequence: MAQSRLFFSADKAEAERTYNILEQAFEDDGFPIAITEIDEDRQIFEVSVYVEDDAEEVAARVDALVGPGLFDTEELPDIDWVTHSLEGLKPVRAGHFFVHGSHDRDKIEPGDIAIEIDAGLAFGTGHHGTTAGCLELIEETVETEHPTNALDLGTGSAVLAIAIARLAPIPILATDIDPIAVTVAAENAAKNGVAEHIVTATAEGFGHPIFRSYSPFDLIVANILANPLIELAPSIKEHLAPGGSIILSGILDSQHDAVLAAYQTQGLTHQKTLHREGWVAIHLK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y371_BUCAI
Sequence: MNHIIETKDAPKPIGPYSQALKIDNFIILSGQIPIDVISNQIPENIAEQTYLVLKNIKLILVHAKFQVHNIIKTTVFTTDLKKINIINEIYKKFFIDNKSNFPARSCVEVQKLPKNVKIEIEAMAFKK
What are the official names of this protein?
RutC family protein BU371.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: GPMI_VIBA3
Sequence: MSAKKPMALVILDGYGYREDNQDNAIANAKTPVLDGLIANQPNTLISASGLDVGLPDGQMGNSEVGHTNIGAGRVVYQDLTRITKSIADGEFGQTEALVNAVDKAVKVDKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHAFLDGRDTPPRSAENTLARFQELFAKLGKGRVASLIGRYYAMDRDNNWDRVQESYDLLTQAKAEFTFDTAVAGLEAAYARDENDEFVKATEIKAEGEESAVIVDGDAVIFMNYRADRAREITRAFVPDFDGFARNVFPAIDFVMLTQYAADIPLLCAFPPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGKEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKGGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLDECLGKVVEAIKEADGQLLITADHGNAEMMVNPETGGIHTAHTNLPVPLIYVGNKDVEFKEGGKLSDLAPTMLSLSGIDIPVEMSGDVIVK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.