PharMolix/UniProtQA huggingface dataset:
Protein: RL23_SHESM
Sequence: MIREERLLKVILAPHISEKSTVNAEKHNTVVFRVAIDATKAEIKAAVAKLFEVEVESVRTLVSKGKTKRTGGRVGRRSDWKKAYVTLAAGADIDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HIS7_GEOSW
Sequence: MVRHASISRTTKETDIQLQFVIDGEGKAELDTGVPFLTHMLDLFTKHGQFNLTVTAKGDTEVDDHHTTEDIGICLGQALREALGDKKGIKRYGNAFVPMDEALAQVIVDLSNRPHFEFRGEFPSEKVGTFDVELVHEFLWKLALEARMNLHVIVHYGRNTHHMIEAVFKALGRALDEATMIDPRVKGVPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_RICB8
Sequence: MSSYKYYDLIRRPVITEKTTLLSEQNKYTFYVDKLAEKLAVKKAIEEIFKVKVKKVNILNVKGKKKRFKGVIGRQVDRKKAVVTLEKDHNIDFAGGIK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SYFB_BUCBP
Sequence: MEFSEKWLLDWLGFSISNVFYEQMTKSGIEVEAIAKISKNFERVIVGEVVERLYVNTMHNIVFLRVKLSEKKMIFSISSNDIEFSRGTKIAIATQDSKLFNNRLISMLRFKEKISEGMVCSFKDLGILNIKNKIVEICSEVPVGTDISKFLWFDDDRIIKVSSAPNRADGMSILGIARDMSALNNLCLPTLKEYHINITNHEKFRILINIPDVCLNFIGRTIQSVNLNRQTPLWILERLRRSSISSENVLVDIINYVLIELGQPIFSFNIHGIVQNIIIRTARDNEQFFDSCSQRVPIDKRTILLSDDKEILVLGNHTNSYNSRLSLSSHNIFLGCALFNPEYINNDSHFNFGFKNKITEYYSRGVDSDIQYKALNYVTYLVLKICGGNASNVVLANSSRVTVIQKKIFVLKKTLHRYVNNIISDTLVVKYLLQLGYLVEKQKHCWLVIPPSWRFDIQIQEDVISDLVRVFGYHNIPACALVTNYKLVHDDNIYTSLNRIKLLLVDLGYNEVITYSFVDSQIQKYLFPKRKQFFLLNPISRKMSSMRLSLWNGLLSSVLYNQNRQEKVMRFFESGLCFEEDGNEYLGVKQDLYLAGVISGYKNETDWRSFNKIVSFYDLKGDIELIMALLRKLDKVSFKKMLFQNLCPKQSAAIYFEREMIGVIGVISSNISKKMGLKYKTIVFELIWKKIAQSNDYRIRDVSLYPRCSRDISIIVNDSIAADEILKVSKNVFLDKIVEVKLFDVFYGKNVGLNKKSLSLRFIFGSSKRTLSEEIISNCLNECIRILQEKFNAILRDRNFLF
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_BUCBP
Sequence: MITGKIVQIIGAVVDVEFSQQSVPKIFNALKVDNQGSILILEVQQQLGSGIVRTIAMGSSNGLKRGLLVVDLEHGIKVPVGTATLGRIVNVLGQPIDMKGPLKNHDNSDIEYWEIHRKAPSYSEQLTSYEVLETGIKVIDLICPFSKGGKVGLFGGAGVGKTVNMMELIRNIATEHSGYSVFTGVGERTREGNDFYHEMSDSRVLDKVSLVYGQMNEPPGNRLRVAFTGLTIAEKFRNEGHDVLLFIDNIYRYTLAGTEVSALLGRIPSAVGYQPTLSEEMGVLQERITSTNKGSITSIQAVYVPADDLTDPSPATTFSHLDSTITLSRQIVSLGIYPAIDPLNSTSRQLDPRIVGQLHYDVALGVRSILQRYQELKDIIAILGMDELSEDDKILVSRARKIQKFLSQPFFVAEIFTGFSGKYVKLQDTINGFKDIIEGKVDHVPEQAFYMVGSINEVIEKSKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PLSX_STAA8
Sequence: MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNHDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DAR12_MOUSE
Sequence: MKKLVLLSAFVLLAFQVQADSIQNTDEEIKTEEQPGEENQAVSISFGDPEGYALQDAAIRRARRCPPCPSCLSCPWCPRCLRCPMCKCNPK
What is the function of this protein?
Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats.  Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins.  It may have microbicidal activities (By similarity).
What are the official names of this protein?
Alpha-defensin-related sequence 12, CRS4C5, Cryptdin-related protein 4C-5, Defensin-related cryptdin-related sequence 12.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPE_SHISS
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PITE_DICDI
Sequence: MVLIKEFRIPLPLTVEEYKVAQLFMVATISKKNTSLGEGIEVIENKPYADGATTGFFTRKIFHLGGRLPTWLRSFAPTSLQIEEKAWNAYPYCKTSYACPLLGDRFSVSIETRYEPDSGTQDNCLNLNSEELSIREVEHIDIVNDPIDEAHYKPEEDPKIFQSVKTGRGKLQNDWMKSTKPIMCCYKVCKVEFRCWGVQNKVENFIQRVALRDTFFMGHRQIFCWIDQWFDMDMESLREFEKKTNEEMKAQFHNNNNNNSNNSNNNNNNNTQPQRSSFFSRSTDGNK
What is the function of this protein?
Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding the lipid in a hydrophobic cavity (By similarity).
What are the official names of this protein?
Phosphatidylinositol transfer protein 5, PtdIns transfer protein 5, DdPITP3.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
Protein: ATPF2_SYNJB
Sequence: MFFPTLLAVEAAEKGGLFDLDATLPLIAIQFLLLVAVLNSLFYEPVTRAIDSRNDYIRTTQAEAQERLDKAVSLTRQYESEISQARLQAQQVIAEAEAAAARIRSEKLAAVQAEIQQKLEAARLQVEQEKQAALEQLQQQVDAIAAQITQKLLGSAR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: LMUB_BACX1
Sequence: MIIIAFSILDFKNKEAQNFDFKAGTNLIVSKGNTKGKSSLLKSMYYTLGFDVHQFPSNWNINFMYFQIEVLINNVKYNITRQKNIFRVSDVEVPLNVKEYSEWLQHKLEIKMQLANTHTKHLYEAYSSAVILPFYIDQDDSWDGGIYRNVTNTLNQYTRIPADIFKSVFNLSNYELLELQNSLTNYSKEKNTVVSTIKSLLNVLEDYRHENADVPTVSKIDKIALNKDIDRYLQMQNELNEQIVKYKMKLLNKQEMLDLQKQELSELEQLLKMNKKRYNSIETECQYCHSKLTKEQSLTRLDLSNNYFEISLLKEEIEKEVVKLTNEIIIFESQQNSIESKIDEIHRRIQNSKDLLTIDDYVKATAKKEASNELESLVDKQVLSKYNLEEKIKVLRREINKLKKEKESLREIIERDYTDLVFEIKKVLNDLNDTKLDLSELNLDELKFLEFKKISGSGMDKNKKFLAYYLIYFSLLRKYSSYIIPFCMDSFIKNEITGETAKKMFEAIEKYFFDTNQSFFSIVSENLKHLEFVDSYNKINVEGKLLVRDKYDEIALKFKFDS
What is the function of this protein?
Component of antiviral defense system Lamassu type I, composed of LmuA and LmuB.  Expression of Lamassu type I in B. subtilis (strain BEST7003) confers resistance to phages phi3T, SpBeta and SPR (PubMed:29371424).  May be an ATPase (Probable).
What are the official names of this protein?
Lamassu protein LmuB, Putative ATPase LmuB.
Protein: HIS3_BRUA2
Sequence: MPRFDASGLITAIVTDARDGELLMVAHMNEEALRLTLETGIAHYWSRSRKTLWKKGETSGNLQSVVELRTDCDQDALWLKVHVAGDGPTCHTGRRSCFYRQVVSSGGKVALTMASDHDQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C73_ORYSJ
Sequence: MGICCSKGKEELEEEGFPWKHDAFFHDQLWSAGVSMHTKQGWKGANQDAMTTCQDFAGHKGQIFCGVFDGHGPLGREVARHVRDVLPVKLSSSLALKTEQDPSSNTDKETLEKSDCTSLSDTSNEKQLLSTWKNIFVKTFEDVDEDLRQHSGIDCICSGTTAVTVVRQGDHLIIANLGDSRAVLCTRDSKDRPISVQLTTDLKPNLPSEAERILNSKGRVFAMDDEPDVPRMWLPDQDAPGLAMARAFGDFCLKSHGLICTPEVYYRKLSAKDDFLVLATDGIWDVLSNKEVIKIVSSATDHSKAAKQLVERAVRTWRRKFPTSMVDDCAVVCLFLKPSPSSSESTPGDAKPPQAVSFTGSFRKVLGGGGGEAEEGTNVWRALEGVARVNSVVRLPRMGAVLSWRRRSTSLEEDDEARID
What are the official names of this protein?
Probable protein phosphatase 2C 73, OsPP2C73.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: YQGV_BACSU
Sequence: MAIADVTIIPIGTETPSVSAYVADVQKILEGYQAEGKIKYQLTPMNTLIEGELSDLFAVIQAIHEAPFQKGLHRVATNIRIDDRRDKKTTLESKIESVNKHLQP
What are the official names of this protein?
UPF0045 protein YqgV.
What is the protein family that this protein belongs to?
Belongs to the UPF0045 family.
Protein: IPRA_SALTY
Sequence: MLSLSKPLQEFYRLDKCLSKHGTRFEFVNDKEIICSPDESNTHTFVILEGVVSLVRGDKVLIGIVQAPFIFGLADGVAKKEAQYKLIAESGCIGYRLSSSQTLAIIEQNQLWREAFCWIVWKSQVLELRDKQLIGNNSYDQIRATLMTMIEWDEELRSRIGVMNYIHQRTRVSRSVVAEVLAALRKGNYIEMNKGKLISINRLPSEY
What is the function of this protein?
Involved in oxidative stress resistance.
What are the official names of this protein?
Inhibitor of hydrogen peroxide resistance.
What is the protein family that this protein belongs to?
Belongs to the IprA family.
Protein: YB34_YEAST
Sequence: MYQNNVLNAILASEKSNFQYDSGTILRNHKRPIITFNNNIEHTVSEPNNFTGYEEKEDLDIMDICPYYPKARMLADAIQHAKTSASENKMELSMKTIPCLKKENVHVEKGHDWSQLSTSRICKILEDIADKKNKTRRQSAPLQKTKYFPTNENQNTDIENQNWSQIPNEDICALIEKIASRRNKNRKRKNLSCSKVQEIQGNIDLPKKDVQEGDISDSSLFAAVRGTKKVSGYDYNSEDKIPNAIRLPYCKQILRLFSLLQMKRNDLIVTSENCNSGVFFSNFNYQLQVKSNCIANISSTLSFLPHHEITVYTSFILYPNVVDNIWECTRYAIQLLKSEAAQFTLLRDIYSGFTIILSNHRYHPKGFSADYCYSANELTLFLFVIRTGQKKVLYRSIPHNTAAIEKDSSFDTENRKRRSEEEVVLKCRKCSNNSLALKEISTYRLDSAEGFEKSQPLKDEAKLSDMNYVQGSISYNRTILTGLWKLFHRLCCKDRYRKTNLSETLFYDDSTERWVRMGELMHY
What are the official names of this protein?
Uncharacterized protein YBR184W.
Protein: LACD2_STRP6
Sequence: MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEILFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase 2, D-tagatose-1,6-bisphosphate aldolase 2, Tagatose-bisphosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: CBIF_SALTI
Sequence: MSETFDPRCVWFVGAGPGDRELITLKGYRLLQQAQVVIYAGSLINTELLDYCPAQAERYDSAELHLEQIIELMAAGVKAGKTVVRLQTGDVSLYGSVREQGEELTRRGIDWQVVPGVSAFLGAAAELGVEYTVPEVSQSLIITRLEGRTPVPAREQLEAFASHQTSMAIYLSVQRIHRVAERLIAGGYPATTPVAVIYKATWPESQTVRGTLADISDKVRDAGIRKTALILVGNFLGKEYHYSRLYAADFSHEYRKA
What is the function of this protein?
Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A.
What are the official names of this protein?
Cobalt-precorrin-4 C(11)-methyltransferase, Cobalt-precorrin-3 methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: BCAT_MONBE
Sequence: MAAALRLTPHMRQAYPVVAAPSVARLSTLDASKLTIETTTQPRERVEKTKLVFGHTFSDHMLKCKWDVNEGWAAPTISPYANLSLAPSSIVLHYAIECFEGMKAFRGDDDRIRLFRPNLNMDRLHRSSVRLALPDFDQDELLKCITELVIKDKDWIPAGRGYSLYLRPTHIGTAEYLGVGKSSSSLLFCINSPSGAYYSTGFKPVSLLADPAYVRAWPGGVGNTKGGCNYAPSIYPQSQAQAQGCQQVLWLFGEDHEVTEVGTMNLFMYWKNEQGEDELITPPLDGTILPGVTRQSIVDMARGWNEFKVSERKFNMGQVSRALKEGRVYEMFGAGTAATVCPIGQIKYLGEDLNVPLALGNSGELTNRIWTDIFDIQYGAVEHEWAPVIA
What is the function of this protein?
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: MTRE_METMA
Sequence: MEPLIGMGVLALIGVAATIAGASEDLESDIGSQSNPNSQVQLAPQMMFPHRIFNKAISGEPPSNALMCSIGAAIATVLISEFTVSPLFALVFGSVIAASVHATFAVTATMGRCASQSRFKQPIYLDMIRSHTPAIMGYAFITTFCVLIVSYLMTVVLGHPFPLTMLAFIWGITIGAIGSSTGDVHYGAEREFQQFEFGSGLNASNSGNIVRYAESGLRNGFDNSWFCSKFGGPTTGIAFGMTVFLGSWITTIFDPAQGLSMGWLSVIAGVIIVLILIIWNWKIEVQARKAYGPYKEDKAEEASA
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSPH_SHIFL
Sequence: MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEVLIPGLRVEFCRVNGLRGPTAANVYLS
What are the official names of this protein?
Cold shock-like protein CspH, CSP-H.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAGHL_HUMAN
Sequence: MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLAELGTLPPETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACGHSRRGMRMTCPLCRRLWARSASTTPSCGWREYGCCPGASTVTWTLRKASGDCVLG
What is the function of this protein?
Hydrolase acting on ester bonds.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PSIP1_MOUSE
Sequence: MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQASTKQSNASSDVEVEEKETNVSKEDTDQEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVDTEEAGMVTAATASNVKASPKRGRPAATEVKIPKPRGRPKVVKQPCPSDGDMVIDEDKSKKKGPEEKQPKKQLKKEEEGQKEEEKPRKEPDKKEGKKEVESKRKNLAKPGVTSTSDSEDEDDQEGEKKRKGGRNFQAAHRRNMLKGQHEKEAGDRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEPTGTKSLNGGSDAQESNHPQHNGDSNEDGKDSREASSKTKPPGEEREAEISLKESTLDN
What is the function of this protein?
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis.  Involved in particular in lens epithelial cell gene regulation and stress responses.  May play an important role in lens epithelial to fiber cell terminal differentiation.  May play a protective role during stress-induced apoptosis (By similarity).
What are the official names of this protein?
PC4 and SFRS1-interacting protein, Lens epithelium-derived growth factor, mLEDGF.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THRC_METGL
Sequence: MKYISTRGQSPALSFSEILLGGLAPDGGLYLPEQYPQFSADALSAMRGMNYRDLAFTILSRLIDDIPADDLRIIVDKTYRADVYAYARPGQDAEDITPTYKLEDDLYLLSLSNGPTLAFKDMAMQLLGNLFEYVLAQKGETTNILGATSGDTGSAAEYAMRGKQGVKVFMLSPHQKMSRFQTAQMFSLQDDNIFNIAVKGVFDDCQDIVKAVSNDHAFKAKNKIGAVNSINWARVAAQVVYYFKGYFAVTADNAQQVSFAVPSGNFGNVCAGHIARMMGLPIAKLVVATNENDVLDEFFKTGVYRPRGSANTYHTSSPSMDISKASNFERFVFDLVGRDAAKVRELWGKVDAGGSFDLNDGGWFAKVADYGFVSGSSNHANRMQTIKATHERYGVTIDTHTADGLKVALEHREAGTPMLVLETALPAKFEDAIVEALGHKPERPHSLEGLESLPQRFEVMEADAAVIKQFIVEHI
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: TATA_BRUA1
Sequence: MGSFSIWHWLIVLAVVLLLFGRGKIPELMGDVAKGIKNFKQGMADEDAKEDPRTIDAKAEEPVKDVKKTTKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FTSQ_CERS4
Sequence: MQSLSFPPNRRTPRLAPPRRETGRRDPAPSRWAYRAQRLWLTPMFRTALRVGLPIVGVLLVVALIFASADRRAAMAGAFTGLVDSFQQRPEFMVTLLSVDGASPELSDRIRATLALKLPLSSFDIDLTAARARIESIDAVAQAEVRVRSGGLLEVRVTEREPAIIWRRAANLVLLDGTGRRVDDLAFRSERGDLAVIAGEGAERAVPEALEILAAARPILERIRGLVRMGERRWDIVLDRGQRIQLPVEEPVAAVERMIALDEAEDLLDRDVISVDLRIKDRPVLRLAPYALNAVRRARGIDTSGSDL
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: PIK1_SCHPO
Sequence: MPSSNSGNELLLRFFESAHFTSQLCVAYLSRYPNNIGIHHFLCEKLATFPYEEIEFFIPQLIHLVLNKDSESVALEEFIISQCEQNTQCALITFWYLQAHMVDLGLQPHSSCFKICKRLYNRIQILVFMSSSSLIQSQQKISENVTPALILSGIMLGGVCVPELLKKAGPIAIAQGRKAPRQDPDESDVDVLRRLSTEPRYSLDVLRSSLNNSIVEQHSEVSLRLKAPELTRTHSYQSSATLSIDEQRRVLRSNYFQQEIQFLFALQDISIRLIIVPRQARLSSLRAELALLNNNLPADVNIPLLRSYHKEVSHKIVRIDPKEATILNSAERVPYLIMVEVLSGELSFEPQSKKNKAKVQKIVSHKNQRKRWFDLTDVDPYTNLQDSTDNDISESESEGGDLSMSPLIKGLVPDTLSLSKSFSSFGNVSLQVPSSHRDTDVVLLSGRHSDSDGNGALKRSKIYASEITARMRAAATMLSQLDAEGSRRPKAETERIKNSIILDMQRLEEERLNEPSIYPVSVDISCAEDLRFGKETQKAERKGDRDDPSAATFQEDWYAKKERIRKSSPYGHYPNWDLVSVIVKTGADLRQETFACQLIYAFQRVWLECKEKVWVRRMKILVTGDNSGLIETITNAISVHSIKKNLTKQLREAELAQGKIAGKNVVTLKDYFIKQFGDPNSSRYRQAQTNFLQSLVAYSIISYLLQLKDRHNGNVLIDSEGHIIHIDFGFLLTNTPGNVGFESAPFKLTADYLEILDDRFDEYRSLMKAAFKSVRKNADQIILLVEVMQNNSTMPCFRAGENTSAQLLQRFQLQLGDKECDDFVDLLIQKANCSVWTRLYDLFQNITNGIY
What is the function of this protein?
Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate.  PIK1 is part of a nuclear phosphoinositide cycle and could control cytokinesis through the actin cytoskeleton (By similarity).
What are the official names of this protein?
Phosphatidylinositol 4-kinase pik1, PI4-kinase, PtdIns-4-kinase.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Golgi apparatus. Nucleus.
Protein: NFASC_CHICK
Sequence: MVLHSHQLTYAGIAFALCLHHLISAIEVPLDSNIQSELPQPPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTLVIDFHGGGRPDDYEGEYQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPLSLQCNPPPGLPPPVIFWMSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNARFHFTHTIQQKNPYTLKVKTKKPHNETSLRNHTDMYSARGVTETTPSFMYPYGTSSSQMVLRGVDLLLECIASGVPAPDIMWYKKGGELPAGKTKLENFNKALRISNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDVPPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEMSMARKEDQGIYTCVATNILGKVEAQVRLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLKDDAPLYIGNRMKKEDDGLTIYGVAEKDQGDYTCVASTELDKDSAKAYLTVLAIPANRLRDLPKERPDRPRDLELSDLAERSVKLTWIPGDDNNSPITDYIVQFEEDRFQPGTWHNHSRYPGNVNSALLSLSPYVNYQFRVIAVNDVGSSLPSMPSERYQTSGARPEINPTGVQGAGTQKNNMEITWTPLNATQAYGPNLRYIVRWRRRDPRGSWYNETVKAPRHVVWNTPIYVPYEIKVQAENDFGRAPEPETYIGYSGEDYPKAAPTDVRIRVLNSTAIALTWTRVHLDTIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGIVSRLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRYLRIRQPNLESINLEWDHPEHPNGVLTGYNLRYQASCLSSPVNGSKTGRTLVENFSPNQTRFTVQRTDPISRYRFFLRARTQVGDGEVIVEESPALLNEATPTPASTWLPPPTTELTPAATIATTTTTATPTTETPPTEIPTTAIPTTTTTTTTTAASTVASTTTTAERAAAATTKQELATNGSSIWDIRAWANSNWANITWSHNYSAGTDFVVKYITSNKTEKSIPVKAQTPSSVQLANLTPGMVYKLWVFPIWSSPSEHSYITFTTSSAYTKNHVDIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVRDNKDEHLNPEDKNVEDGSFDYRSLESDEDNKPLPNSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAIYSLA
What is the function of this protein?
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.
What are the official names of this protein?
Neurofascin.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NDHI_LAGRA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CEBPE_HUMAN
Sequence: MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAVKPAPEARGLKGPGTPAFPHYLPPDPRPFAYPPHTFGPDRKALGPGIYSSPGSYDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPCSPLLKAPSPAGPLHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLRNLFRQIPEAANLIKGVGGCS
What is the function of this protein?
Transcriptional activator (PubMed:26019275).  C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.  Required for the promyelocyte-myelocyte transition in myeloid differentiation (PubMed:10359588).
What are the official names of this protein?
CCAAT/enhancer-binding protein epsilon, C/EBP epsilon.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.