PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_HALH5
Sequence: MGDIVVIKCGGSVLDSLSDSFFTSVRRLQAEGAKPIIVHGGGPAINGMLAKLEVETTFVDGLRKTTDSVLSVAEMVLCGQTNKKVVRKLQKAGVKSIGLSGSDGELVRVKAIDEAILGYVGEPVHVNGELLHMLVADGFVPVLAPIGVNDEFEPYNVNADTVAGAVATALQAKELIFVTDVAGILKDDELVPALTPEEVESLIEEGTIYGGMIPKVRSAIHSLTGTLEAVSIVNGNDVFFAESGKLIGTTIKKQVIHSQG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
Protein: HIS4_PROA2
Sequence: MLIIPAIDIKDGKCVRLTRGDFDQQKIYLDNPRDMAIIWRKQNAKMLHVVDLDAALTGTMVNFEKIREIVATLDIPVQVGGGIRSFEDVERYLGIGVSRVVIGSAAVTNPQLIAELLATFSPSQIVVGIDAENGIPKIKGWTESSSMQDYELALEMKKLGVKRIIYTDISRDGMMQGVGYESTRRFAMKAGMRVTASGGVTSSDDLKKLQTLEQYGVDSVIVGKALYESNFPCQQLWYNYEKGMGIDCNFTTASVRGKCCF
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_DESOH
Sequence: MRIGTGYDLHRLVKGRRLVLGGVALPFEKGLDGHSDADVLVHAVCDALLGAAGLGDIGDHFPDTDARFKGVSSLLLLTETGRMLKEKGFFVVNIDATVLAQAPKLGAHKAAMAANMATALGIDAACVNVKATTTEGLDAVGRGEAMAAMSVALIIEEEARDSRGQGAG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: M2_I91A0
Sequence: MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILDRLFFKFIYRRLKYGLKRGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: TRHO_PSYA2
Sequence: MSTSETNNIKAPNHVTEYDSVTNNIVVAALYKFTRFADFEEYREPILNIMLDNEVKGTLLIASEGINGTISGTRQGIDNVLEYLRSIDAIGSFTFKESYTDAQPFYRTKVKLKKEIVTMGVENIDPLQSVGRYVKPSDWNALISDPDVILIDTRNDYEVKIGTFQNAVNPNTETFREFPEYVAKELDPAKHKKVAMFCTGGIRCEKSTAFMREQGFEEVYHLEGGILKYLEEVPASDSMWEGDCFVFDNRVSVNHNLEKGSYEQCFACRMPITQAEMQSPAYIKGESCPHCIDKATDEQKARFREREHQMQLAQKRGEAHIGSDVIDVIEKRKAAKIEARRQADEANKAKAD
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: DTD_SHEPA
Sequence: MIALIQRVSEAKVVVDGATIGEIDKGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQARELYEAFVDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BORDL
Sequence: MVQMQTYLTVADNTGGKIAQCIKVLGGSKRRYAKVGDIIVIAVKQAIPNSPVKKGDVHKAVIIRTSKEIRRKNGTYVRFDDNACVILDANLNPRGKRVFGPVARELRDANFMKVVSLASEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MBI3_YEAST
Sequence: MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFNMEDPYYSNMMLNKSVLCWNIFIWMMNYYIIQLIIYNNMIWNKNNMVKMFIMRRKLAVINMYMYMKLIIQRTYSYYMNNTIIYDKNHKLNTDNPIYAYIGGLFEGDGWITISKKGKYLLYELGIEMHIRDIQLLYKIKNILGIGKVTIKKLKMKDGTIKEMCKFNVRNKNHLKNIIIPIFDKYPMLTNKHYDYLYFKDNLLKDIKYYNDLSYYLRPIKPFNTTEDILNKNYFSSWLIGFFEAESCFSIYKPMNKKMKTASFEVSQNNSMEVMLAIKSYLKITQNIYTDKFNNSRMTTKSINGIKNVVMFINNNPIKLLGYKKLQYLLFLKDLRTITKYNNYFKIPPKY
What is the function of this protein?
Mitochondrial mRNA maturase required for splicing of intron 3 of the cytochrome b (COB) gene, containing its own coding sequence.  In vivo splicing requires the formation of a ribonucleoprotein complex together with the imported mitochondrial RNA-splicing protein MRS1.  The complex seems to stimulate the intrinsic ribozyme activity of intron bI3 through binding to and stabilizing specific secondary and tertiary structure elements in the RNA.
What are the official names of this protein?
Cytochrome b mRNA maturase bI3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSMB_ESCF3
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAVAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIIEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHVLPGFEEGWVTVQDASAQGCMAWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGILIYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECF_ASPOR
Sequence: MSTPGAQEVLFRTGIAAVNSTNHLRVYFQDSHGSIRESLYESGWANGTAKNVIAKAKLGTPLAATSKELKNIRVYSLTEDNVLQEAAYDSGSGWYNGALAGAKFTVAPYSRIGSVFLAGTNALQLRIYAQKTDNTIQEYMWNGDGWKEGTNLGVALPGTGIGVTCWRYTDYDGPSIRVWFQTDNLKLVQRAYDPHTGWYKELTTIFDKAPPRCAIAATNFNPGKSSIYMRIYFVNSDNTIWQVCWDHGQGYHDKRTITPVIQGSEIAIISWEGPELRLYFQNGTYVSAISEWTWGKAHGSQLGRRALPPAE
What is the function of this protein?
Lectin that specifically binds to L-fucose and weakly reacts with mannose and N-acetyl-neuraminic acid (PubMed:12092808, PubMed:27318092, PubMed:28041800).  Has strongest preference for the alpha-1,6-fucosylated chain (core fucose) on glycoproteins among alpha-1,2-, alpha-1,3-, alpha-1,4-, and alpha-1,6-fucosylated chains (PubMed:17383961, PubMed:19109923).  Binds to fucose residues of IgE in mice and human, causing antigen-independent IgE-mediated mast cell activation and anaphylactoid reactions in mice and is possibly implicated in allergic response to Aspergillus oryzae in humans (PubMed:21790704).  Induces secretion of pro-inflammatory cytokines IL6 and IL8 implicated in ocular diseases such as mycotic keratitis, probably through its interaction with host toll-like receptors TLR2 and TLR4, followed by up-regulation of pro-inflammatory cytokines (PubMed:28470344).
What are the official names of this protein?
Fucose-specific lectin, Aspergillus oryzea lectin, AOL.
What is the protein family that this protein belongs to?
Belongs to the fungal fucose-specific lectin family.
Protein: GLPT4_ARATH
Sequence: MAMNSKRKTPPGIALLRRVRGRNWSPKTFRYAILFITFIAYACYHASRKPSSIVKSVLHPDSSTKPPQEHNSDKIYPWPMGNVFVKREIGDIDEVLLHRKSKGWEPFNGKDGTSRLGEIDVAFLACYSIGMYVAGHLGDSLDLRLFLTWGMIGSGFFVGLFGMGYFWNIHAFWFFLVMQMAAGLFQATGWPSVVAVVGNWFGKRKRGLIMGIWNAHTSVGNICGSLIAAGVLEYGWGWSFIAPGFVMSLGGVLVYLFLAAYPEDVGFPDINSNSGKFIKRKRDVEEEEEEVEEDLGTDVEGDGEGSSGSGSGYENKRSVGLLQACMIPGVIPFALCLFFSKLVAYTFLYWLPFYLSQTTIGGEYVSVKTAGNLSTLFDVGGIVGGILCGYISDKFKARATTAAAFMYAAIPAMLVYHSYGGVSQTVNILLMMVAGLFVNGPYALITTAVSADLGTHKSLQGDSRALATVTAIIDGTGSAGAALGPLLTGFLSTLGWQAVFYMLVVGALCAGLLLTRLVIAEIREKLGYVDEEVPASEPLLTDRR
What are the official names of this protein?
Putative glycerol-3-phosphate transporter 4, G-3-P transporter 4, Glycerol-3-phosphate permease 4, AtG3Pp4, G-3-P permease 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CH602_TRIV2
Sequence: MAKIISFDEESRRALERGVNALADAVKITLGPKGRNVLLEKKYGTPQIVNDGITVAKEIELEDPLENTGARLIQEVAAKTKDVAGDGTTTATVLVQALIKEGLKNVAAGSNPVSLKRGIDKTTEALVAEIAKVAKPVEGSAIAQVATVSAGNDEEVGAMIAQAVEKVTKDGVITVEESKSLTTELDVVEGMQIDRGYISPYFITNNERQTVELENVRILITDKKISSIQELVPVLEKVARLGQPLLIIAEDVEGDALATLVVNKARGVLSVAAIKAPGFGERRKALLQDIAILTDGQLISEEIGLSLDTASLEALGTAQKITIEKDNTTIVAGNTTKPEIQKRIAQIRRQLEETDSEYDSEKLQERIAKLAGGIAVIKVGAATETELKDRKLRIEDALNATKAAVAEGIVPGGGKTLIYLASKVDEIKKNFDEEEKIGADIVKRALEAPLRQIADNAGVEGSVIVSRVKDSDFNTGYNAATGEFEDLIAAGIIDPAKVVRSALQNAASIAGLVLTTEAIVVEKPEKKAAAPADAGMGGMGGMGGMGGMGGMGGMGGMGMF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR6B1_HUMAN
Sequence: MELENQTRVTKFILVGFPGSLSMRAAMFLIFLVAYILTVAENVIIILLVLQNRPLHKPMYFFLANLSFLETWYISVTVPKLLFSFWSVNNSISFTLCMIQLYFFIALMCTECVLLAAMAYDRYVAICRPLHYPTIMSHGLCFRLALGSWAIGFGISLAKIYFISCLSFCGPNVINHFFCDISPVLNLSCTDMSITELVDFILALVIFLFPLFITVLSYGCILATILCMPTGKQKAFSTCASHLVVVTIFYSAIIFMYARPRVIHAFNMNKIISIFYAIVTPSLNPFIYCLRNREVKEALKKLAYCQASRSD
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6B1, Olfactory receptor 7-3, OR7-3, Olfactory receptor OR7-9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTH_SHEON
Sequence: MKSVNHLVLTPGSLSLAQLREISRHKLTLELAPEAINDINISAQIVQKVLDEGRTVYGINTGFGLLANTKIAPEDLQLLQRSIVLSHAAGTGQYMQDATVRLMMVLKINSLSRGFSGIRLEVINFLISLVNAEVYPCVPEKGSVGASGDLAPLAHMCLPLLGEGEMSYQGQIISAAEGLEIAGLKPIDLAAKEGLALLNGTQASTALALEGLFHAEDLFAASSVIGAMSVEAAMGSRSPFDPRIHAARGQKGQIDSAMVFRYLLGEESEISLSHANCEKVQDPYSLRCQPQVLGACLTQIRQAAEVLATEANGVTDNPLVFQDTGDIISGGNFHAEPVAMAADNLAIAIAELGAIAERRIALLIDSSLSKLPPFLVKNGGVNSGFMIAQVTAAALASENKTYAHPASVDSLPTSANQEDHVSMATFAARRLRDMSENTRGVLAIELLAAAQGLDFRAPLTPSKAVAQAKAELREVVAYYDKDRYFAPDIEAATDLLYTASFNAYLPLGVLPSL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_SALPA
Sequence: MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQADLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAANAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFPLYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: PTLY_BACLI
Sequence: MKKLISIIFIFVLGVVGSLTAAVSAEAASALNSGKVNPLADFSLKGFAALNGGTTGGEGGQTVTVTTGDQLIAALKNKNANTPLKIYVNGTITTSNTSASKIDVKDVSNVSIVGSGTKGELKGIGIKIWRANNIIIRNLKIHEVASGDKDAIGIEGPSKNIWVDHNELYHSLNVDKDYYDGLFDVKRDAEYITFSWNYVHDGWKSMLMGSSDSDNYNRTITFHHNWFENLNSRVPSFRFGEGHIYNNYFNKIIDSGINSRMGARIRIENNLFENAKDPIVSWYSSSPGYWHVSNNKFVNSRGSMPTTSTTTYNPPYSYSLDNVDNVKSIVKQNAGVGKINP
What is the function of this protein?
Cleaves unsaturated oligo-galacturonides from pectin.  The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced.  Activity on methylated pectins decreases with an increasing degree of methylation.
What are the official names of this protein?
Pectate trisaccharide-lyase, Exopolygalacturonate lyase, Pectate lyase A, PelA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_XANC8
Sequence: MAQSKRVKAIAAAVVPGKTYAFEDAIKILKTSTKAKFVESIDVAVRLGVDAKKSDQQVRGSTVLPAGTGKSVRVAVFAPAGAKADEALAAGAEAVGMDDLAEKMQAGDLNYDVVIATPDAMRVVGKLGTLLGPRGLMPNPKVGTVSPNPGEAVKNAKSGQVRYRTDKAGIIHCTIGKASFDDEALKSNLQALLLDLVKAKPATSKGTYLQKVSVSSTMGPGVTVDQSSLSLK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: YETF_BACSU
Sequence: MGNYLSVAVELVCGLGILFIILKLLGKTQFSQITPFDFISALILGELVGNAVYDHEIKIKEIIFASLLWGVLIYIIEFITQKMKSSRKFLEGEPNIVIRKGELQYKVMKKNKIDINQLQSLLRQAGSFSIQEVEYAILETNGMVSVLPKSDFDKPTNKDLQIPSKSVSLPITLIIDGEIVRDNLKEAGVDEQWLKQELKKKNIDKTEDVLFAEWHKNKPLYTVTYEQSRST
What are the official names of this protein?
UPF0702 transmembrane protein YetF.
What is the protein family that this protein belongs to?
Belongs to the UPF0702 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPOL_HBVG3
Sequence: MPLSYQHFRRLLLLDEEAGPLEEELPRLADEDLNRRVAEDLHLQLPNVSIPWTHKVGNFTGLYSSTIPVFNPDWQTPSFPNIHLHQDIITKCEQFVGPLTVNEKRRLKLVMPARFFPNSTKYLPLDKGIKPYYPENVVNHYFQTRHYLHTLWKAGILYKRETSRSASFCGSPYTWEQDLQHGAFLDGPSRVGKEPFRQQSSRIPSRSPVGPSIQSKYQQSRLGLQSQKGPLARGQQGRSWSLWTRVHPSTRRPFGVEPSVSGHTNNFASRSASCLHQSSVREAAYSHLSTTKRQSSSGHAVELYSIPPSSTKSQSQGPVFSCWWLQFRDSEPCSDYCLSHLVNLLQDWGPCTEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGSARVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLSRYVARLSSDSRILDHQYGTLQNLHDSCSRQLYVSLMLLYKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQEHITQKIKQCFRKLPVNRPIDWKVCQRITGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLCKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLCRPLLRLPFLPTTGRTSLYAVSPSVPSHLPDRVHFASPLHVTWKPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: CODY_GEOKA
Sequence: MNLLEKTRKINAMLQKAAGRPVNFKEMAETLCEVIEANVFVVSRRGKLLGFAIKQSIENERMKRMLEERQFPEEYTKNLFNITETSPNIDINSEYTAFPVENRDLFKTGLTTIVPINGGGERLGTLILSRLDREFDNDDLILAEYGATVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLSELEKLKSS
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKT_PICST
Sequence: MSSVDQKAISTIRLLAVDAVAAANSGHPGAPLGLAPAAHAVFKKMRFNPKDTKWINRDRFVLSNGHACALLYSMLVLYGYDLTVEDLKKFRQLGSKTPGHPENTDVPGAEVTTGPLGQGICNGVGIALAQAQFAATYNKPDFPISDSYTYVFLGDGCLMEGVSSEASSLAGHLQLGNLIAFWDDNKISIDGSTEVAFTEDVIARYKSYGWHIVEVSDADTDITAIAAAIDEAKKVTNKPTLVRLTTTIGFGSLAQGTHGVHGAPLKADDIKQLKTKWGFNPEESFAVPAEVTASYNEHVAENQKIQQQWNELFAAYKQKYPELGAELQRRLDGKLPENWDKALPVYTPADAAVATRKLSEIVLSKIIPEVPEIIGGSADLTPSNLTKAKGTVDFQPAATGLGDYSGRYIRYGVREHAMGAIMNGIAAFGANYKNYGGTFLNFVSYAAGAVRLSALSEFPITWVATHDSIGLGEDGPTHQPIETLAHFRATPNISVWRPADGNETSAAYKSAIESTHTPHILALTRQNLPQLEGSSIEKASKGGYTLVQQDKADIIIVATGSEVSLAVDALKVLEGQGIKAGVVSLPDQLTFDKQSEEYKLSVLPDGVPILSVEVMSTFGWSKYSHQQFGLNRFGASGKAPEIFKLFEFTPEGVAERAAKTVAFYKGKDVVSPLRSAF
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: PP123_ARATH
Sequence: MIRAKHISNLSSSARSFFLSGSRPSAADGNSCTCAEDESGVSKRQQIRTEVVQTGKRASNLAAGLAGSILPVEAGKPLVVPKTVEHFTRPSLLPQHVSSPALPGKADSVNHASAIIKEDVGVPIGDQIFKAGIGNVNLLSDIANYKIPLSDGTEVVGLPKSCMVDPTRPISGVKSSNVKVIRREHLAKVYPRSADRVPINSSPGTKQASNDVAGKSFEAHDLLSNNVSGKRKIMPQRPYTDSTRYASGGCDYSVHSSDDRTIISSVEGFGKPSREMMKVTPRTAPTPRQHCNPGYVVENVSSILRRFKWGHAAEEALHNFGFRMDAYQANQVLKQMDNYANALGFFYWLKRQPGFKHDGHTYTTMVGNLGRAKQFGEINKLLDEMVRDGCKPNTVTYNRLIHSYGRANYLKEAMNVFNQMQEAGCEPDRVTYCTLIDIHAKAGFLDIAMDMYQRMQEAGLSPDTFTYSVIINCLGKAGHLPAAHRLFCEMVGQGCTPNLVTFNIMIALHAKARNYETALKLYRDMQNAGFQPDKVTYSIVMEVLGHCGFLEEAEGVFAEMQRKNWVPDEPVYGLLVDLWGKAGNVDKAWQWYQAMLQAGLRPNVPTCNSLLSTFLRVHRMSEAYNLLQSMLALGLHPSLQTYTLLLSCCTDARSNFDMGFCGQLMAVSGHPAHMFLLKMPPAGPDGQKVRDHVSNFLDFMHSEDRESKRGLMDAVVDFLHKSGLKEEAGSVWEVAAGKNVYPDALREKSYSYWLINLHVMSEGTAVIALSRTLAWFRKQMLVSGDCPSRIDIVTGWGRRSRVTGTSMVRQAVEELLNIFNFPFFTENGNSGCFVGSGEPLKNWLLESYVERMHLL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g74750.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: HMN11_HUMAN
Sequence: MATRGFSCLLLVISEIDLSVKRWV
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 11, HN11, MT-RNR2-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: CITD_VIBC3
Sequence: MKIAHPAFAGTLESSDLQVRIEPNNDGGIELVLDSTVEQRFGHAIRQVVLHTLDAMQVHDALVTIEDKGALDCVIRARVQAAVMRACDVQNIEWSQLS
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_NOSP7
Sequence: MATLQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRRIYCVLRSPHVDKDSREHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YBEY_CORK4
Sequence: MSIEVFNESGYDGVNEEALIDVAQFALMRMDIHPAADMTISIVDEPTIEDLHVRWLNLEGPTDVMSFPMDELTPGSGRPDADAPGPAMLGDIVLCPAFAERQAHRAGHGLGHELSLLTVHGILHLLGYDHVAPEEERRMFALQNDILADWYTDLEERGVSYGPKPTGPGAFPTAADREALDQDMIKSTVGGMLAEPTDRDKS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 122R_IIV6
Sequence: MTDKMGTDLTSFRGNLNGLYEAIKVQTALQKEAKTIKREQKKIKDEIDTFKTAILEDLKQRDQEGVEFKGLKITIHPKPKRVYFKKADKERLICEALRNCGIEDAQSKTKNVIDAISQIHTETEDTLKIIDSKKEKKVNKY
What are the official names of this protein?
Uncharacterized protein 122R.