PharMolix/UniProtQA huggingface dataset:
Protein: MCHR1_MACMU
Sequence: ACAPGQGGRRWRLPQPAWVEGSSAWLWEPATGTGWMDLEASLLPTGPNTSNTSDGPDNLTSAGSPPRSGSVSYINIIMPSVFGTICLLGIIGNSMVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRAVSNAQTADEERTESKGT
What is the function of this protein?
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
What are the official names of this protein?
Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROBM_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGQDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GSH1_ECOHS
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: Y942_CERS1
Sequence: MKITWLGHSGFRIAIEQAVLLVDPWLTGNPLFPADRREEALAGATHILITHGHGDHTGDTVAIAKERGLPVVGIYDLVTWLQEKEGIDGIGFNKGGTVTLGGARVTMVQATHSSSMSGEAGPIYTGTESGYMIAGEGHVIYLSGDTDIMADMGWMGEYHRPDVGILSAGGHFTMDMKRAAFAARRYFDFRTVIPCHYRTFPLLEQSAEALKEGLPGVEVIEPQVLVPIEI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Rsph17029_0942.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: ARGDC_SULIA
Sequence: MSEQEVLQKNNSPEGKEDRIIGKHVFGNLYDIDAERLNDKEFLEKLVLEAVNIAHMKLVEIKAWSFGGKKGGVSVIALVEESHIALHTWNEYNYATLDVYTCGEDSDPQSAFAHIVNALNPKRYQMFYADRSSQ
What is the function of this protein?
Specifically catalyzes the decarboxylation of L-arginine to agmatine.  Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.
What are the official names of this protein?
Arginine decarboxylase proenzyme, ADC, ArgDC, Pyruvoyl-dependent arginine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: RS14_RHOPA
Sequence: MAKKSAIEKNNRRKKMTKNAAPKRARLKAIIADKSKPMEERFAATLKLAEMPRNSSATRIRNRCDLTGRPRSVYRLNKLSRIAIRDLGSRGLVLGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14, RRP-S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: MED21_KLULA
Sequence: MTDRLTQLQICLDQMMEQFCGAVNYVDKNHGFEPSNDSEEQMSDPQAHIVEEKEFEKNIDELTTDIILKTRQIMALIDSLPGVDVSAQEQLHRIDSLQKQLIKMEKEKIDAIKRKDALQEKVRTLTQDFTIGINESKTEARLV
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR5_BACAC
Sequence: MANAYKQAGVDIEAGYEAVSRMKKHVQTTMRKEVLGGLGGFGGMFDLSKFALEEPVLVSGTDGVGTKLMLAFMADKHDTIGIDAVAMCVNDIVVQGAEPLFFLDYIACGKAEPSKIENIVKGISEGCRQAGCALIGGETAEMPGMYSTEEYDLAGFTVGIVDKKKIVTGEKIEAGHVLIGLASSGIHSNGYSLVRKVLLEDGELSLDRIYGRLELPLGEELLKPTKIYVKPILELLKNHEVYGMAHITGGGFIENIPRMLPEGIGAEIELGSWKIQPIFSLLQEVGKLEEKEMFNIFNMGIGMVVAVKEEDAKDIVRLLEEQGETARIIGRTVQGAGVTFNGGKAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1302_STAA3
Sequence: MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETLSEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEALKNRFVVIHVDYIDGDILKNVIKEQSLLQGDKQIEQIIKFNEDLRTMSKQGQISEEAASIRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF
What are the official names of this protein?
Uncharacterized protein SAUSA300_1302.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: AROQ_RALPJ
Sequence: MADKPIAKALRNVLVLHGPNLNLLGTREPEVYGATTLADINTALVERATARGVTLAHFQSNHEGALVDRIHAAKSEGIEFIIINPAAYTHTSVALRDALAGVVIPYIEVHLSNVHRREPFRHHSYLADQAVGVICGLGWRGYLAALDFAIDQHGG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ARC_THECD
Sequence: MAARDDAGARKAQHDAEIHDLRSQVSMLEEEVSVLRRKLAESPRQIRVLEDRLHETQAKLAAVTGQNERLVATLKEAREQIIALKEEVDRLAQPPSGFGVFLGAREDGTVDIFTGGRKLRVNVSPSVDVSQLKQGQEVLLNEALNVVEALGYETQGEVVMLKELFDDGERALVIAHADEERVIKLAEPLRGVPLRAGDSLMLEPRSGYAYEKIHKAEVEELVLEEVPDITYEEIGGLGPQIEQIRDAVELPYLHADLFREHKLRPPKGVLLYGPPGCGKTLIAKAVANSLAKQVAEKTGQEGKSFFLNIKGPELLNKYVGETERHIRLVFQRAREKASAGTPVIVFFDEMDSIFRTRGSGVSSDVENTIVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAKDIFSKYLVPGLPLHPDDLAEHGGSEEATIEAMIQRVVERMYAETEENRFLEVTYANGDKEVLYFKDFNSGAMIQNIVDRAKKMAIKQYLETGQKGLRVSHLLAACVDEFSENEDLPNTTNPDDWARISGKKGERIVYIRTLVSGKAGSEAGRSIDTVANTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: RS8_PORGI
Sequence: MTDPIADYLTRLRNAIMAGHRVVSVPASNIKKEITKILFDKGYILNYKFEENDSQGIIKVALKYDLAHKVNAIKKLKRVSRPGLRKYVGYRDMPRVLNGLGIAIVSTPRGVMTDKEARELKVGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: OCAT2_HUMAN
Sequence: MSEKPKVYQGVRVKITVKELLQQRRAHQAASGGTRSGGSSVHLSDPVAPSSAGLYFEPEPISSTPNYLQRGEFSSCVSCEENSSCLDQIFDSYLQTEMHPEPLLNSTQSAPHHFPDSFQATPFCFNQSLIPGSPSNSSILSGSLDYSYSPVQLPSYAPENYNSPASLDTRTCGYPPEDHSYQHLSSHAQYSCFSSATTSICYCASCEAEDLDALQAAEYFYPSTDCVDFAPSAAATSDFYKRETNCDICYS
What is the function of this protein?
Transcriptional coactivator that specifically associates with POU2F3 (PubMed:35576971).  This complex drives the development of tuft cells, a rare a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (PubMed:35576971).
What are the official names of this protein?
POU class 2 homeobox associating factor 3, Cancer susceptibility candidate protein 13, Colorectal cancer-associated protein 2, Protein OCA-T2.
What is the protein family that this protein belongs to?
Belongs to the POU2AF family.
Protein: KCY_RICAH
Sequence: MVDLKTKAFDFAKNFAIALDGPAASGKGTIGLILAKKFSLQYFQSSIVYRQLAFDCINQKIDVTDMDAVIALSKALKLDSHLDLEHESIGDMASQIAVISEVRNNLNKYLINLVKTTPRIIMEGRDIGTVVVPEADLKIFITANPQIRAERRYKQLQAKGKKCILDEILRQIILRDKRDKERKAAPLLPASDALIIDTSELSAMEVVEEVTNYIKNKIA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIA2_MAIZE
Sequence: PQKLGLPVGRHVYVCASIGGKLCMRAYTPTSPVDEVGHFDLLIKIYFKDEDPKYPNGGLMSQYLDSLPLGATIDIKGPHRHIEYTGRRRFVVNGKQRHARRLAMIQAGRGTTPDDDTEQAVLRDQPDDDTEMHLVYANRTDHDMLLREEIDRAWLPRTRRLKVWYVVSKVPEDGWEYGVGRVDEHVMREHLPLGDSETIALVCGPPAMIECTVRPGLEKMGYDLDKACLVF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NAD(P)H], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: RRF_ALBFT
Sequence: MTIAEIKNTVEGKMDQSIEAFKHNLTKIRTGRANPALLDTVHVDYYGAMLPISQVANVSLLDARTISVQPWEKGMGAKIEKAIRDSDLGLNPSSMGDLIRVPMPAMSEERRKELSKVVRGEGEGAKIAIRNLRRDANEAIRKAVKDKLASEDEQKRCETDIQKVTDRHVIVIDQLVAAKEQDIMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_BORPD
Sequence: MPRPIHASISLAALAHNLDVVRRHLDQAAQAAGGAPPSIWAVIKANAYGHGIEAAVAGFSAAQGLAMLDLAEAVRCREAGWGGPILLLEGFFQPADLDLIDRYHLSATVHTREQLDMLAQARLSRRVDIMLKLNSGMNRLGFDPDAYGSAHARALQLREQGVVGAVGRMTHFACADGTPGVAGQLRVFQSVTQGLADGPVSVCNSAATLRYPEIAVAHGAQAHWVRPGICLYGASPFADADAASFGLRPAMSLRSQIIGVQDLPAGAEVGYGATFRAERPMRVGVVACGYADGYPRHAGTGTPVVVGGVRTRLVGRVSMDMLMVDLDPVPAAGIGTPVSLWGQDGPSVDEVAQAAGTIGYELLCALAPRVPVKRDS
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FNBA_STAAS
Sequence: MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATENKVNETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEEAPKAVQAPQTAQPANLETVKEEVVKEEAKPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTASESKPRVTRSADVVEAKEASDEKVETGTDVTSKVTVESGSIEAPQGNKVEPHAGQRVVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEILGNGNIRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPVVYNPGVSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAGGQPTVKVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLDKTYVIHYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADGNGKNGQIIQNNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIQGQNNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPQIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA
What is the function of this protein?
Promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin.  This confers to S. aureus the ability to invade endothelial cells.  Promotes adherence to and aggregation of activated platelets (By similarity).
What are the official names of this protein?
Fibronectin-binding protein A.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: MTOX_SHIB3
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETVDGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: TS1R2_PONPY
Sequence: MGPRATTICSLFFLLWVLAEPAENSDFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKVIGYNLMQDMRFSVEEINNDSSLLPGVLLGYEMVDVCYVSNNVQPVLYFLAHEDNLLPIQEDYSDYVSRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERLARRDICIAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYDFFNEVLRQNFTGAVWIASESWAIDPVLHNLTELRHTGTFLGITIQSVPIPGFSEFRERDSQAGPPPLGKTSQRSTCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDHSTCTKRVVYPWQLLEEIWKVNFTLLDHQIFFDPQGDMALHLEIVQWQWDRSQNPFQSVASYHPLQRQLKNIQDISWHTINNTIPVSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPSNEWSYQSETSCFKRQLAFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPMVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIICAFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLNPTTRTDPDDPKIMIVSCNPNYRNSLLFNTSLDLLLSVVGFSFANMGKELPTNYNEAKFITLSMTFYFTSSISLCTFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSVIQGYTMTRD
What is the function of this protein?
Putative taste receptor.  TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity).
What are the official names of this protein?
Taste receptor type 1 member 2, Sweet taste receptor T1R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO3B_HELPY
Sequence: MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSDIGLKSYIFTQSSDKEGVGTINGKKFLDIISCLKDSNIILETKDDSLAIKQNKSSFKLPMFDADEFPEFPVIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKRELAGILMQFDQKHQTLSVVGTDTKRLSYTQLEKISIHSTEEDISCILPKRALLEILKLFYENFSFKSDGMLAVIENEMHTFFTKLIDGNYPDYQKILPKEYISSFTLGKEEFKESIKLCSSLSSTIKLTLEKNNALFESLDSEHSETAKTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLIQESLDEKQSHLNAKISTLMMPITL
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHMA_ECOLI
Sequence: MNALLSNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGSY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde.  2-keto-3-deoxy-L-mannonate, 2-keto-3-deoxy-L-lyxonate and 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) are also reasonably good substrates, although 2-keto-3-deoxy-L-rhamnonate is likely to be the physiological substrate.
What are the official names of this protein?
2-keto-3-deoxy-L-rhamnonate aldolase, KDR aldolase, 2-dehydro-3-deoxyrhamnonate aldolase, 2-keto-3-deoxy acid sugar aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily.
Protein: DYL2_DROME
Sequence: MSDRKAVIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAFIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYLGQVAILLFKSG
What is the function of this protein?
Acts as a non-catalytic accessory component of a dynein complex.
What are the official names of this protein?
Dynein light chain 2, cytoplasmic, 8 kDa dynein light chain.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ARGB_THET2
Sequence: MSEALLVKVGGSLRGAEALLDELAAYPGPLVLVHGGGPEIGAWLGRLGYESRFVGGLRVTPPEQLEVVEMALYLTGKRLAEGLSRRGRKALALSGRDALCLKGRALPELGRVGEVVEVEVGLLQDLLAKGYTPLLAPIALDAEGPLNVNADTAAGAVAGALGWPAVFLTDVEGVYRDPKDPRTRFPRLTPKEVEALKGEGVIQGGMIPKVEAALSALRAGAPWAAIAKGERGVLEAVLRGEAGTRFTL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRE28_YEAS7
Sequence: MDTGSASIKDYETVLTDIEDSIAVSSEEVLNNQELRLKNTLHEITSSILAINEENKFVNPLRNDESLDVEGKEVFVNPKILSAKIKEFNKLMELLKLTYLEQETLDYFFRFTLSSTKPLQLDSEKDPQFVKLNERVNDLKEEISNVQESKIEQIKAEIQETGHNFAEKQDLINELYLEATGDIENCWDSLNELKNLTNKEDKNMMGEKDTILNSSDSDDFVEETYTNWQKLLFLQKQNQRLTKELKEMHEVKNQIIRKGEQSKKEDSGHLMANESELCQSINLLTKFWEKHFLLKGSKTTILNFEIFTQLGKVQFEIKDMQYIIAISLSDLKRPMIKDITILQKAGGNIVTDIEANSKFNNKYRNNTKVQIFEVMDDIISELTNE
What is the function of this protein?
Forms a kinetochore complex with SPC105 which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3).  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: PIPB2_SALCH
Sequence: MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIETMAETLKSTMPDRGAPLPENIILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIPLVSFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTAENLCDADLSGANLEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLLGCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEDAVLTRANLRKASFISTNLDGADLAEANLNNTCFKDCTLTHLRTEDATMSTSTQTLFNEFYSENI
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells.  Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane.  Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery.  Required for virulence, but not for intracellular survival and replication in phagocytic cells (By similarity).
What are the official names of this protein?
Secreted effector protein PipB2, Type III effector PipB2.
What are the subcellular locations of this protein?
Secreted. Host membrane. Note=Secreted via the type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell.
Protein: PCP3_AMPCA
Sequence: DGIADASKKFSDATYPIAEKFDWGGSSAVAKYIADASASNPRQAALAVEKLLETGLTMDPKLVRAAVAAHSKALDTAVSNPKLVASKEDFAAVNEALARMIASADKQKFAALRTAFPESRELQSSLFAGNNGYEAEKAYDSFKALTSAVRDASINGANAPVIAEAARSERYVPDGPVGRAAKKFSEATYPIMEKLNWVKSPEISKYLATASSKDPKMMAPGIDKTLEVALTMNQNLINNAVYAHVRAIKGALNTPGFVAERDDFARVNLALAKMIGSADPAKFKALLTAFPGNADLQMALFAANPEQAKAAYETFVALTSAVV
What is the function of this protein?
Water-soluble antenna for capture of solar energy in the blue-green range.  Peridinin is an asymmetric carotenoid.
What are the official names of this protein?
Peridinin-chlorophyll a-binding protein 3, PCP.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEU1_BUCRP
Sequence: MNSQVIIFDTTLRDGEQALQASLSVKQKLQIALSLENTGIDIIEVGFPISSPGDFKSVQTISKNIKNSRICSLARCLDKDIDAAAEAMHSSNAFRIHIFLATSILHMESKLKKNFDQIIDMAITSVKRALRYTDDVEFSCEDASRTTMDNLCRIVEKLINAGVKTINIPDTVGYTVPNELSSIIHNLFQRVPNIDKSIISVHCHNDLGMAVGNSISAIQAGARQIEGTINGIGERAGNTALEEVIIAIKVREDVLGVSTKIKHKEIYRTSQIISQICNLPIPPNKAIVGSNAFAHSSGIHQDGVLKNRKNYEIMEPSSIGLKEVKLNLTSRSGRAAVKHYMTEMGYRECDYKIDELYASFLKLADKKGQVFDYDLEALAFINQQQEELEHFSLSFFSVQSISNGLSTASVKLLCGKKTFIESATTSNGPIDAIYQALNRITHFPIILQKYQLIAKGKGKDALGQVDILVEHKKRKFHGMGLATDIIESSAQAMVNVLNNIWKANQVNEKLKKLKKINN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: OR4KD_HUMAN
Sequence: MERANHSVVSEFILLGLSKSQNLQILFFLGFSVVFVGIVLGNLLILVTVTFDSLLHTPMYFLLSNLSCIDMILASFATPKMIVDFLRERKTISWWGCYSQMFFMHLLGGSEMMLLVAMAIDRYVAICKPLHYMTIMSPRVLTGLLLSSYAVGFVHSSSQMAFMLTLPFCGPNVIDSFFCDLPLVIKLACKDTYILQLLVIADSGLLSLVCFLLLLVSYGVIIFSVRYRAASRSSKAFSTLSAHITVVTLFFAPCVFIYVWPFSRYSVDKILSVFYTIFTPLLNPIIYTLRNQEVKAAIKKRLCI
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4K13, Olfactory receptor OR14-27.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.