PharMolix/UniProtQA huggingface dataset:
Protein: PYREL_METB6
Sequence: MSSLDDLIARAKLLLSEGHSPGQIADELSLSMETVTWLLTQANGGSAAPKDVHIDWTAVSSQAPLLDGIALMLLNRYYGAQKDPAAASADVIVGIALSGIPLATVISVQEAAQLAIYHPAKQNASEHPVGSISGNFAPVAKERCIIVDDVITSGNTMREVVKYLKKHGAVPVAIWVIFDKRGIRDIDGVPVYSLFKISRID
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: ASNA_ECOSM
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMADGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPNLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWSAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCML4_MOUSE
Sequence: MQTQRVPGRKRGRPPLHSTRVQMAVHNLYSASAASVPAVTIPKKRGRKPRYKIKSPVLMTPLALSPPRSTPEPDLSSIPQDAATIPSLVVPEALTVCLYINKQADVGPYLERRKLQQLPERLGPERPATVLQQAVQACIDCAHQPRLVFSLVKQGYRGELVSVSASFDGKQHLRSLPVVNSVGYVLRFLTKLCRSLLCDNLFSHLPFPGSIGASDKAQEREDGRTESAKVATAEECLANAVGMNRYAMDFSHRGSVTHSSSLYKRLTCGDSHLAGGPATTTSGSRTNPVPSGGSSSPGLRLPASSPKRNGTAIEGNRCAPSPSPEVQDTRRPSSRNPSTWTVEDVVRFVKDADPEALGPHVELFRKHEIDGNALLLLRSDMIMKYLGLKLGPALKLCYHIDKLKQAKF
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
What are the official names of this protein?
Sex comb on midleg-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the SCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANMK_ERWT9
Sequence: MKSGRYIGVMSGTSLDGVDVVMAVIDENMVAQQARYHHPMPQALRQQILAVCQGQSLTLSQLGQLDTRLGRLFAEAVLALLKQQGLSGEEITAIGCHGQTVWHEPQGEAPNTLQIGDNNQIAALTGITVVGDFRRRDMALGGQGAPLVPAFHHAVLMHPAERRMVLNIGGIANLSLLLPGRELRGFDTGPGNMLLDAWIWRQQGKAYDKDGAWGAGGQIVWPLLKQMLSDPYFALSAPKSTGREYFNLGWLEQQLHSFPGLPAQDVQATLTELTATTIAQQVLLSGGCDRLLVCGGGGKNQLLMTRLAAQLAGIEVTSTDKAGISGDDMEALAFAWLAWRTLSGLPGNLPSVTGARAASVIGAIYPANRSLPL
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: LDOX_MAIZE
Sequence: MESSPLLQLPAARVEALSLSGLSAIPPEYVRPADERAGLGDAFDLARTHANDHTAPRIPVVDISPFLDSSSQQQQRDECVEAVRAAAADWGVMHIAGHGIPAELMDRLRAAGTAFFALPVQDKEAYANDPAAGRLQGYGSRLATNTCGQREWEDYLFHLVHPDGLADHALWPAYPPDYIAATRDFGRRTRDLASTLLAILSMGLLGTDRGDALEKALTTTTTRTAADDDLLLQLKINYYPRCPQPELAVGVEAHTDVSALSFILHNGVPGLQVLHGARWVTARHEPGTIIVHVGDALEILSNGRYTSVLHRGLVNREAVRISWVVFCEPPPDSVLLHPLPELVTEGHPARFTPRTFKQHLDRKLFKKKQQHKAKAEEEDGGNGDHHRHEPPPQTN
What is the function of this protein?
Oxidation of leucoanthocyanidins into anthocyanidins.
What are the official names of this protein?
Leucoanthocyanidin dioxygenase, LDOX, Leucocyanidin oxygenase, Leucoanthocyanidin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PF23B_XENLA
Sequence: MLETTNGEASPEDPPLNLKSLSQPPQKRSRTVEDFNRFCSFVLTYAGYIPTPATEERPWTPPSSVSPHRTEESDGWDSSPQLPVPSDPPQPPATSDISTIETFVMKAKSQGGGGNSIMKTGGPIGGSGEQVKKGSRRKRRQLHRGGVTMSDTDTDEEERDKRPAGSLPAPQLPPSAESSRDGGGSSSDTDTQVMDEDIMVESGDDSWDLVTCYCEKPFAGRPMIECNICCTWVHLSCAKIRKSNVPDVYYCQKCRGGRGSGGTALKEEP
What is the function of this protein?
Acts as a negative regulator of autophagy.
What are the official names of this protein?
PHD finger protein 23B.
What is the protein family that this protein belongs to?
Belongs to the PHF23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RXL7_GEOKA
Sequence: MSYEKVLQAGKIVIGTKQTIRALKEGKAAEVIVAEDADLPIIEKVTAAANEANVPVTKVDSMKKLGKACKIQVGAAAVAILR
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: ARHG6_RAT
Sequence: MNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDDLYSGANFSKVLNTLLAVNKATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTRLDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLHKRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASFQQGTRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDESIRAESSSKTSILQ
What is the function of this protein?
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 6, Rac/Cdc42 guanine nucleotide exchange factor 6.
What are the subcellular locations of this protein?
Cell projection, lamellipodium.
Protein: CPSF6_XENLA
Sequence: MADGVDHIDIYADVGEEFNQEAEYGAHDQIELYEDVLSPSANNGDAPEDRDYMDNLAASVGDDVVKGSVPNIVYTYTGKRIALYIGNLTWWTTDEDLTDAVHSLGVNDILEIKFFENRANGQSKGFALICVSSESSSKKLMDLLPKREMHGQKPIVTPCNKQFLSQFEMQSRKTATQAGQMSGEGKAGPPGINARLPFPPGGRGRGRFPTSGPGGDRFPGPAGPGGPPPPFSAGMTPPRPPMCPPGPPGPPGPPPPGQPLPPPLPGPPNRGERPPPPVMFPGQPYGQPSIVTLPPGPPPPGYGPPPGPPPPQQGPPPPPGAFPPRPPGPPMALGPPPHLPGPPPGGPPPAPHVNPNFFPPPGNAGMTSSDSRGPPPSDPYGRPPPYERGDYGPPGRDMDVVRTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRERDRDRERDREREYRHR
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  Plays a role in mRNA export.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 6.
What is the protein family that this protein belongs to?
Belongs to the RRM CPSF6/7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: RPOC_IDILO
Sequence: MKDLLKLLKPTNQAEEFDGIRIALSSPDMIRSWSYGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVTEGGLTSLEQGQILTEDEYLDALEEHGDEFDAKMGAEAVLDLLRAVDIDGDVQKLREELPETNSETKRKKISKRLKLLEAFQVSNNKPEWMILKVLPILPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPKLRLHQCGLPKKMALELFKPFIYGKLERRGLATTIKAAKKMVERETAEVWDVLDEVIKEHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHLPLTLEAQLEARALMMSTNNVLSPASGDPIIVPSQDVVLGLYYMTKEKINGKGEGMVFKDPNEAEKAYRTGQVELHSRVRVRITDTTIDDDGNRTTKTELRDTTCGRAILSLIMPEGLPFELINQAMGKKPIGRMLNKAYRDLGLKDTVVFADQIMYTGFHYAMVSGASVGINDMVIPEAKKEIVSAAEEEVAEIQEQFESGLVTAGEKYNKVIDIWSTANEKVSKAMMDNLSKEIVKNKDGEDEEQASFNSVFMMADSGARGSPAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVSQDVVIMEEDCGTYEGLYMKPLIEGGDVVEPLRERVLGRVLCEPVMKPGSEEELLPRNTLLDEKMCDVLEENSIDEVKVRSVITCDTDFGVCAHCYGRDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRATAENNIQVKNPGTIKLHNAKWVVNSDKAHVITSRSTELTLTDEYGRERERYKVPYGAVLKKGEGDSVDGGETVANWDPHTHPIITEVEGRIKFVDLIDGVTMTRQTDELTGLSSIVVLETGQRTSAGKDMRPMVKLVDGKGNDVNIAGTDIPAQYFLPGNAIINLEDNSEVKIGDTLARIPQEGSKTRDITGGLPRVADLFEARKPKEPAILAEKTGTVSFGKETKGKRRLLITPTDGGDQHEEMIPKWRQLNVFEGEQVTKGEVIADGPEAPHDILRLRGVSAVANYIVNEVQEVYRLQGVKINDKHIETIVRQMLRKALILRAGDTNLLEGEMVEMSEVLAANAKAEADGKKPAIFERQLLGITKASLSTESFISAASFQETTRVLTEAAVGGKKDSLRGLKENVIVGRLIPAGTGYSYHKERMQRRLDELNVDIEPTMTAEQAEQQLADALNAGNSSAGDDSAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CY41_TRYBB
Sequence: MHWQEGGGRGCVYTHGNCRRNLTARALQALQHVEALTCHYCVSLLHLLPLLLMWMPPVCADDSAVTVNVLSMMYNPEYYVEKVNAINAGFDASLSAHGWKTGSGATISVIRPPSYNTTAEDIFQLGVKQSEGKLLVVFGPLGTDPVVWVRDKLKENDLVAIAPIAYSSEVRGWNPHLYSISVEPNAELLALIRYAVVYLGLPRVGLMYAKGNGFDKESYEFTMRIMEIMGRKPCGVFAVESSGGRDVLEGQLNTKWGQFVATRPQAVLLFSSLEEETTGWFVKKIAQDNRTVDMYLLAPSSFQHFLIKTWSDALVSLNRTFTPGQLITTGTVPLASDNRSSMVRHFQRDMDNYLDTNSDWKGFAKPEHYLKDDKLGEMMVFGWLAGEVLFEALNNAPQLTNRTSFMESLYKQRRYVIDDFVVGDFGGECDEALHYRVPCVIAIKAAAWTHMRVVDDSLSLKPMKKGSVTWSVSECSSANVQVSAPLIGLYVVLTDDKVAQRASMRWSLGARSIEEADDVDKRIFFHSLKVNLKNLTQSLEQVRDTKAVAAVLGVTADILSVPNMTFIGPIPLFPRLNKFWRNVIHLQPLLAHELYVLAVYLSNTSSTGVKALVRGGEASEVVDTLDKSLVTFGVSLDSSKTLGDGDPMSSYLSGNGDVFCIGLTPPDVAAVARHLQTHLRARVFVPFNDILLFYQEFVAGFNASKESIASSEGLLFATSFPHWGKKNRKSDMVARFHRHVNESHWDPLTFLGFATTRLLQVVISNMRKVNAEPLADRIYTESNIRVDDVGFGPFSDAECVSGTSVSANECASNFGATNISVWSMGACAEFKLAQDTGWDDTVYGLCYSARGSTHTVTDSWNNFWVCIRLVIIYCPWCVPTHLPAERRNNNRAPKEPTDPVTLIFTDIESSTALWAAHPDLMPDAVAAHHRMVRSLIGRYKCYEVKTVGDSFMIASKSPFAAVQLAQELQLCFLHHDWGTNALDDSYREFEEQRAEGECEYTPPTAHMDPEVYSRLWNGLRVRVGIHTGLCDIIRHDEVTKGYDYYGRTPNMAARTESVANGGQVLMTHAAYMSLSAEDRKQIDVTALGDVALRGVSDPVKMYQLNTVPSRNFAALRLDREYFFDEGEDGTTTSTSDHSSSRADVSESGQIIATALQSLLSTFKTAHREKLLLPYCERWRVPLPRKAASEWDDAYCEEVVRRIAVKVGRVADHGADSGSESSSTQGSSSIIIVPFYDMHLQEY
What is the function of this protein?
Could act as a receptor for an unknown ligand.
What are the official names of this protein?
Receptor-type adenylate cyclase GRESAG 4.1, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACPS_RHOP2
Sequence: MIIGIGSDLIDITRIAKVIDRHGERFLDRIFTETEQARAGRRDKQPNLVAATYAKRFAAKEACSKALGTGIRQGVWWRDMGVVNQRGGRPTMLLTGGARARLDALTPPGMTAQIDLSITDEWPLAQAFVVISAIPAATSGT
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL24L_ALTSX
Sequence: MKCLKTLLVSTTLLGAFSLNAEVTLEQQIKITDEGLHFDGRNLDFSNVGSPDTGEKYDYFFGPNISAHGDAVKTYKHYVFMTWYKGGKNERNVMLSRYNTLSGELSTIEFPHRHTGFRGDPLVGESHNTIGLAVSPINGTIHMVFDMHAYDDNNHGGKFKDDFFRYSYSVPGAAELPHSEFTLDKFVKDTSEVSQGDDDYKHLTMTGDLGDKGNFARLTYPKFFTTVDGTLLLYMRLGGNNNGAYVFNRYDAEAEKWSTFTPFNENNQKSKGNPYNWGLYGNMKYINGKLRVGFQQRSSDNTDKYKYQNGVFYAYSDHPDGFGDWKNHKGEPMTWPLINSDEIKVFEPGDYISHTEANSVYIVGSFDWTVTEKGDIHIISKVRSTDRNRPDYEEVYIHSYKPAGADEFIISTDFTGASEIYTSGDNVYIVGLEGGRPYVEKAQGGTNNFVRVYKATDGPVFDHGTLYIKDGKVYYYLMERTSGNAMPLYLQIIDLDLESDANAPLVSFPSPSLTVEQGFEKLSLNISAESPVEGRFIQSVSLYINDELVRTDDSMPYLFGHGSKPHETGAMGWLDTHEPNPSPLPAGTHIFKAVAVDSEGDSAIATMVLNVNSNAPIVSFPQESLEVDEGFEKLSLNISAESAVEGRSIESVSLYINGELVRTDTSLPYLFGHASKPHETGAMGWLDTHSTNPSPLTAGTYEFTAVAIDSEGEESTASMQLVVKGEPQPPAVTWPNSTVTVYEGYEKLAITIDAESPVEGRDIQSVTLYRNGELVRVDTRPVWNFGHSFAPYEFGAMGWLDRHEPNPSPLGVGTHTFTAVAKDSTGLEGESDMTLIVLSLPGPSITINESDVSLLTEYQNLAITADASTANDDITIVSLALYLNEQLVREIYEPPFEWGGENYSDELLDLPVGTHLAKVVATDSNNNQTEASMFVTIELLGDLNKDSVVDNKDIRLFTAALRNGEEMNIRYDFNDDGVVNNRDTRGLVHRCTYSRCGSN
What is the function of this protein?
Ulvan lyase involved in ulvan degradation (PubMed:28958183).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl).  Ulvan lyase catalyzes preferentially the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acid GlcA, but not IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end.  The most abundant end products in the degradation of the ulvan polysaccharide were deltaUA-Rha3S disaccharides and deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides (By similarity).
What are the official names of this protein?
Ulvan lyase, long isoform, Ulvan lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 24 family.
Protein: COAD_LACGA
Sequence: MTKAIFPGSFDPITNGHAEVVEAAARMFEKLYVVIMTNTSKKYLFDEKERLDLAKKVFENDKNIEVIARPAELTVEVAHELNAGAIVRGLRNTTDFNYERDIAGINKTLDPKLNTVLLFTRPEDSFISSSMIKETVFFGGNVSTLVPKPVAAALEEKLRNQNNEEK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_PROMH
Sequence: MAAKDVKFGIDARNKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPVITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIIAEGLKAVAAGMNPMDLKRGIDKAVVGAVEELKKLSVPCSDTKAIAQVGTISANSDETVGTLIAQAMEKVGKEGVITVEEGTGLEDELDVVEGMQFDRGYLSPYFINKPETGTAELENPFILLVDKKVSNIRELLPVLEGVAKANKPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTNGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGLGEQEAISGRVAQIRQQIEDATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKRARVDDALHATRAAVEEGVVAGGGTALVRVANALREMTGDNEEQTVGIRVALRAMEAPMRQIVANAGEEPSVVVNDVKAGQGNYGYNAATEAYGDMIEMGILDPTKVTRSALQFAASIAGLMITTEAMVTDLPKDEKMDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VINC_CHICK
Sequence: MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVSAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNTKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQMTDQLADLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMSEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEHLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPVTVINEAAEAGVDIDEEDDADVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ
What is the function of this protein?
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion.  Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex.  May also play important roles in cell morphology and locomotion.
What are the official names of this protein?
Vinculin, Metavinculin.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, adherens junction. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Note=Recruitment to cell-cell junctions occurs in a myosin II-dependent manner (PubMed:20584916). Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (PubMed:20086044).
Protein: RHG15_BOVIN
Sequence: MQKSTNSDIPVETLNPTRQGTGAVQMRIKNANSHHDRLSQSKSMILTEVGKVTEPISRHRRNHSQHILKDVIPPLEQLMVEKEGYLQKAKIADGGKKLRKNWTTSWIVLSSRKIEFYKESKQQALSNMKTGNKPESVDLCGAHIEWAKEKSSRKNVFQITTLSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDPSSHSRNLELFKIQRSSSTELLSHYDSDTKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHTLCEREKSTVPRFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRDLPEPLFPYSFFEQFVEAIKKQDNNTRIEAIKSLVQKLPPPNRDTMKVLFGHLTKIVARASKNLMSTHSLGIVFGPTLLRAEDESGNMAVHMVYQNQIAELMLSAYDQIFS
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.  Has activity toward RAC1.  Overexpression results in an increase in actin stress fibers and cell contraction (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 15, ArhGAP15, Rho-type GTPase-activating protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RK16_FAGEA
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNRICFGRYALQALEPAWITSRQIEAGRRAMTRNARRGGKLWVRIFPDKPVTVRPAETRMGSGKGSPEYWVAVVKPGRILYEISGVPEKIARKAISIAASKMPIRTQFLISE
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NST1_SCHPO
Sequence: MNDKALRTEALSVGLEPPSFKDLLIPIPNSGTKKKNKKKKKPKAKKNVETQANVDLLGSAGTDSAVTDVGANNGVIDHQASLELSNLNSRISHPQLVSANGDDSSLINVEGISSTDWQFTLESDDTIEHSPQCILSTSSFVDEAEFPVHIPGLEDATSSNMSPNSVQNNMNLNTVALGSSTSSKRKKKKKKKSKANSASLNVDDQRDFEQVYSTDVAITYRNGQALSYYNGSVRQASMNNNVNNNKSKDIWSSSNTEEREQIREFWLSLSESERRSLVKVEKEAVLQKMKEQQKYSCSCSVCGRKRLAIEEELEVLYDAYYEELEQYANIQRNLANTESVNASDEGSDKSQKGIISDSPKLLSIPLNNVPSKSLNDDITQDELNSSNADVDEEVIETTSLEEKNVDNQEFVTSISNGNQTLEDTSHSPQTQPPFQPPYPSKADEKNSYHSDLYNFGSSLTVKGGILTVADDLLKNDGKKFIEMMEQLAERRMQREDNSNFHEPELYESGLEYDEDEEEDEEDVDEDELDLMTDEQRMEEGRRMFQIFAARLFEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKKQLKLAKEEERQRREAERLAEQAAQKALEAKRQEEARKKREEQRLKREQEKKQQELERQKREEKQKQKEREKKLKKQQQEADREKMAREQRLREEEEKRILEERKRREKLDKEEEERRRRELLEKESEEKERRLREAKIAAFFAPNQTKEGSDGCTTSSQLGLFEKKGDLVNDEDKLSSHLLDSVPNALRQAPIGLKNTNNLSERNASSNLLNSSLFSSFNSVNPLISLEPNPLNRTLNNSVNLTDFGRKPNGLHSPSSLLSNSNNFGLNPNARHSLSRANSPVHHYPFATPPSQRANKYPLNNGANVPALLNSFSSPQLSPLVNRVLNEPSSSPLSSSSLKSPLSKEGVLNQQGHEQYNFSLSPSIRNKLSPICRPSQGSSPKLKNNLSNTEERMGSRALLDDKTDSVITASNSTTSGLSRDESSNPNNYELLNAFNQNTWKISRSTSNKSLIPESPWGVALGAFTPNASTQSIPWGNRTWTD
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein nst1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PARDP
Sequence: MSVKPEHYDVIVKPIITEKATLVSDANAYVFEVAKDSSKPAIKQAVEALFNVKVKAVNTTITKGKTKRFRGRPGVRSDVKKAYVTLEAGNSIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EFG1_SHEFN
Sequence: MARTTPIERYRNIGIVAHVDAGKTTTTERVLFYTGMSHKIGEVHDGAATTDWMVQEQERGITITSAAVTTFWRGMEAQFAEHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQADKYHVPRLVFVNKMDRAGADFDRVINQIRNRLGATCVPIQLNIGAEENFKGVIDLIKMKAINWSETDQGMTFTYEDIPANLAAKAAEMHEYLVEAAAEASDELMNKYLEEGELSEVEIKTALRQRTINNEIVLATCGSAFKNKGVQAVLDAVVDFLPAPIDVPAITGIDESENEVKRPPDDNAPFAALAFKIATDPFVGTLTFIRVYSGVLESGAGVYNSVKQKRERVGRIVQMHANDRTELKEVRAGDIAAAIGLKDVTTGDTLCDNNHRVILERMDFPEPVITIAVEPRSKADQDKMGIALQKLAAEDPSFKVETDEESAQTLISGMGELHLDIIVDRMRREFGVECNVGKPQVAYRETIRSKVEVEGKFVRQSGGRGQFGHVWLRIEPLEEGAGYEFVNEIVGGVVPREFIPAVDKGIQEQMKNGVLAGYPVLDVRVSLFDGSYHDVDSNEMAFKIAGSMGFKKGALEATPVLLEPCMKVEVTTPEDYMGDVVGDLNRRRGIIEGMDDGIAGVKLVHAVVPLSEMFGYATDLRSASQGRASYSMEFLKYTDAPQNIAKAIIESRN
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_STRSY
Sequence: MTKRALISVSDKNGIVEFAQELTKLGWEIISTGGTKVALDNAGVATIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDHEIGLIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEIAEQGQTTYPTRQRLAAKVFRHTAAYDALIADYFTKQVGEDKPEKLTITYDLNQPMRYGENPQQNADFYQNALPTDYSIAAAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQAETIEKAWDYAYEADPVSIFGGIVVLNREVDAATAEKMHPIFLEIIIAPSYSAEALAILTNKKKNLRILELAFDAQDASEVEKEFTGVVGGLLVQDQDVVVESPADWQVVTERQPSEQEWAAMEFAWKSSKYVKSNGIIITNDKMTLGVGPGQTNRVASVRIAIEQAKDRLEGAVLASDAFFPFADNVEEIAAAGIKAIIQPGGSVRDQDSIDMANKYGLTMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: WNT1_EVATR
Sequence: SGTCTIETCWMRLPTFRSVGEFLKDRFDGASRVALRNEGVRGNSNRGDRGDRRDRGDRSDNGGTEANFQPYNSNHKPPGPRDLVYFDDSPDFCVRNERAGTLGTVGRECNNTSLGVDGCDLMCCGRDYDGSEVRIKERCSCTF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.
What are the official names of this protein?
Protein Wnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RL36_ORITB
Sequence: MKVVSSLKSLKNRDKSCQVVKRRGKIFVINKKNKKFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.