PharMolix/UniProtQA huggingface dataset:
Protein: SORF2_CAEEL
Sequence: MPEEEFEWNESKLNALSEILTQWAPHDELKLENVILEAKMAWIHESTDAVALEKEFEKLLNTSFDPLMDYEEHQRVKNGVCSPAKSTKLDWITKWANIAEKLSISHINCSKAPHKTINFQRLQILPNMTSILAIAHTEADNVILIYGHTKEGIDFQTVLRHSYSNIPDGSLQTIHFLTKNLLDLYSQLFSRKITAEFKTRHFRCLPSFWLQYDVLAPIFEQFRAPRAPRIPLDEATSNWANRKWENYQYLTYLNDITGRVRGEVHNHPIFPWVCDFSEENGGFRQLNRTKYRLCKGDDQLREMYSREPSHHVPELLSDIGYMVYRARVEPKDNLCRHVRRKWVPEEYPSTMSRMYQWTPDECIPEFYDDPSIFNSCHPDMADLRFPEFVSSPQEFIEWHRKMLEHEEVSMNLHRWIDLVFGFNLAIDNSKNALNLHLCFVEKNRRGLRTTGMVQLFNRPHPIRMPLNYDPKLDNYHLKMESFGFGMTSEHRKEPEVEPDEDSHYQIYQKIKKVRRLRHNTYFSSMVSAMEVMAQIVLAPHLAGRFDDPDHIRRCIQLYSYRIPANYRRLFDFLFNTEQDFPDCDEFSFFVSVRLNIPTKILNFSEEFGKCVSLHILRKLDVIPPFSKRSQLIILKEVESLKKSIRLCDHMEQCVVAAFQQLLEDEEACIQSVHRLMPVITRSLSQSALEDLINPMIELIQCETSVKLLDRRFLMHVSICYGTHTFLDLFLPPIVEACASMNCDRSVVAKESIMWLAKRYGPVICAKFISSNVLRIMASCYEAFEMVGLEQQPKAVFNVVLQGDETCSRIESLLSEIVLTYSVTFITVQFLPFCVDLIEQFHKRSSVQLEPGLVSVFRIVELSIRSMSDHQLMNYLEEFIIQKVIYRVLTILLDASFQFSSMRVRIIIICKVCQLLHSITQKIGTENTRIYANQPFKLMFSTFSEIYETDEELRINLRKRPSENTLFEVPLWMVEDVVDKFAKEWGVPFLSSFCDDPAFLIPFVSNSSSSSSPPASIAHSPPSAFTAYSLGGMSSGNRLFSLSASSPVNSVNSLGGLSFCDSGSLSAVWCARVSAAVCGVDNYRFDHLSLCNYTGHQEKIRKLAAISNENSFVSASSDKTVKLWSIKPELDEIGCQWTYQKHTRPVHDITILADNSIASTDGVLHVWDPFRTTLLAQMEWDSKEGSGGNIMRVENVDRHILSAICSLHSTVKLFDSRVGGWTCELKVSPGPGLTRAITVRDKGNKMAVALSNGTLAILDARNGKINALAQTNSTHTVSVNWLSDTRLLVCDADECGIFLETNPRAHIVRKLQDPVSAACLTDNSLVTLQNGTILRVYRNSGELQIETKIRPDELPGTPTAVLPLPLNCSYLIGSSHGAIRLMC
What is the function of this protein?
Together with sorf-1 negatively regulates the levels of phosphatidylinositol 3-phosphate (PtdIns3P) to enable the conversion of early endosomes to late endosomes.  Binds to sorf-1 and the sorf-1-sorf-2 complex likely acts through bec-1, a non-catalytic subunit of phosphatidylinositol 3-kinase (PI3K), to suppress PI3K activity, thereby negatively regulating endosomal PtdIns3P levels.
What are the official names of this protein?
Suppressor of organelle fusion 2, WD repeat-containing protein 81 homolog sorf-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR81 family.
What are the subcellular locations of this protein?
Early endosome. Late endosome. Cytoplasm.
Protein: CDHR5_RAT
Sequence: MGAPALLWPPLLLPLLTVLFGHLPGTLAQAQVCSANQTVFTMNENTTVSGPLADIFVPEDQYVTLGQLSTPNAFKVEGNKLFLIVTPDYEENSLLEAVLECKRGDTLVTQFRVFVAVLDINDNAPEFPFTIKEYNVSEDTRVNTIVIPETELKATDADKDDILVYTLQEVTPNASKFFSLVGINSPALKLDQTLDYYKSPNMTFRLLARDTREENVIPSHTATATVVLNVLPADLRTPWFLPCSFTDDYFCIQAQYHTVIPTGHKLPSPLILSPGPIYAVDGDQAINQPIVYSIMMGNTDDTFIINKDDGNLTMAKSIPSPMTFTLVVRAEQADMARYSVTQAVVEARDVTGNPLQFSQSLYFGTVVLGSEAGTAVKDKTFPSEILRIQAQYLGFPDLNSAVTYQVTNSSEFIMNKDILLTTVPMETERTIRIEVEANNTVTKDIATTIVEIQVSEREPPSTESPTPPEAGGTTGPSSNTTLETPSTSGTSQGPATTSSGGSAGPFPPAGTTLSPLTSAPTVPGGSPTLGISTSPQTATPGGDATQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPRPGTSQPMVPTPGASTSSQPATPSGSTQTPKPGTSQPTTTGPISGVGELGDGQRFSTVDMAVLGGVLGALLLLALIFLIILIHKHYRHRFTCCSGKAKEPQPSGYDNLTFLPDNKAKWSPTSNRKPEPGPEPVQPPLRPPSPMSSSPTPPSSMPPSPQPKASGSPKTVQAGDSPSAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDDDPDQKKSLRLGAVADNTYV
What is the function of this protein?
Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli.  Thereby, controls the packing of microvilli at the apical membrane of epithelial cells.  Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC.  This complex plays a central role in microvilli and epithelial brush border differentiation.
What are the official names of this protein?
Cadherin-related family member 5, GP100, Mu-protocadherin.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell projection, microvillus membrane; Single-pass type I membrane protein.
Protein: VME1_IBVK
Sequence: MSNETNCTLDFEQSVELFKEYNLFITAFLLFLTIILQYGYATRIRFIYILKMIVLWCFWPLNIAVGVISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSCRLFKRCRSWWSFNPESNAVGSILLTNGQQCNFAIESVPMVLAPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTADRRNIYRMVQKYTGDQSGNKKRFATFVYAKQSVDTGELESVATGGSSLYT
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: STPAP_XENTR
Sequence: MEAEESSSSVVPLPQDVQSVVRGGFRCLLCGVNIPNRPSLTDHLSGRRHVRLHEERDKRNQQQERSVYVSNFPRETSEEQLRDVFQKISPVRNIVMDKDRGLYAIVEFESKDGMCAALEEPQIKLSGKRLRVKPREKKEFQRKKGGSPRTLQPPDPEALSKELLNCADVEQQIKKLVSLCSPSHHESHLRELLLSLLQETFTEFFPGCQLLPFGSSVNGFEISGCDLDLYLDLGDDEAENVEGKAEKEIQNREESSTDMEVSMEDPETERKEEEMEIGNSKNDEDEDVTPGLSLKGLSSEEILEVVGKVLRHCVPGVHGVQSVPTARRPVIHFQHKTSGLRGDVTLNNRLALRNSSFLRLCSDLDARVPQLVYTVRYWARVNQLAGNPFGGGPLLNNYALTLLVFFFLQTRNPPVLPTLVHLREETANEVPQVIDGWDCSFPSDPAQVKESGNQQSLSSLLSEFFSFYASLDLHLLILCPCNGLTIPLPFSSPPPAWSEGFRLGPLNIQDPFELSHNVCGNVSSRAARRFISHCAAAARICRTPNYNLHSTSHPWGITPILLPPPTERECVGRGGTEISIPLGGVSPEKTYAAVSKVFVDVLLCTLEEGREDSCQEGKALELSTKHAKAQCKVEKNEVGGELGEQEVPCKAEQNNTKEASKQKSIFKTEEGMTESARRKREMTEPCMSDMTNGKKRRLEFTRGIWDHHLATSAMEEEMCGEAHKDSKTKIDYSNNGTAQWELLVWHRVWEGRRKERRRKQKGEADGVELEIAVSQALALEKEDKCDGPLMKLILTAQLTVKESLQLYLTPKFDPQGLSSTFFHFLESYLPRMVAQIQGCGDPV
What is the function of this protein?
Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs.  In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs.  In addition to adenylyltransferase activity, also has uridylyltransferase activity.  However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase.
What are the official names of this protein?
Speckle targeted PIP5K1A-regulated poly(A) polymerase, Star-PAP, RNA-binding motif protein 21, RNA-binding protein 21, U6 snRNA-specific terminal uridylyltransferase 1, U6-TUTase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus speckle.
Protein: MCD4_SCHPO
Sequence: MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKNITYTIHEKVN
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 1, Immunosuppresant and temperature-sensitive protein 8.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
Protein: PROB_MYCTO
Sequence: MRSPHRDAIRTARGLVVKVGTTALTTPSGMFDAGRLAGLAEAVERRMKAGSDVVIVSSGAIAAGIEPLGLSRRPKDLATKQAAASVGQVALVNSWSAAFARYGRTVGQVLLTAHDISMRVQHTNAQRTLDRLRALHAVAIVNENDTVATNEIRFGDNDRLSALVAHLVGADALVLLSDIDGLYDCDPRKTADATFIPEVSGPADLDGVVAGRSSHLGTGGMASKVSAALLAADAGVPVLLAPAADAATALADASVGTVFAARPARLSARRFWVRYAAEATGALTLDAGAVRAVVRQRRSLLAAGITAVSGRFCGGDVVELRAPDAAMVARGVVAYDASELATMVGRSTSELPGELRRPVVHADDLVAVSAKQAKQV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIP2_DICDI
Sequence: MNKSIYALLCLLLLISFAAAAEKKEEEKKDYGSVIGIDLGTTYSCVGVFKKGKVEIIPNDQGNRITPSYVAFTETERLIGEAAKNQATLNPENTIFDIKRLIGRRFDDEEVQRDMKLLPYKIVSKNNKPYVVVKVKGEEKTYSPEEISAMILGRMKEIAEASLGKTVTHAVVTCPAYFNDAQRAATKDAGVIAGLEVLRVINEPTAAALAYGFDATGDKEKNILVYDLGGGTFDVSVLSIEDGVFEVRSTNGDTHLGGEDFDQRVMKHFLTVFQKKTGKDASKDKKSLQKLRRAAENAKRILSTSPQTQLEIENFFDGKDLIETLTRAKFEELNMDLFKKTLDPVKKVLEDAKFKKSQIHEVVLVGGSTRIPKIQQLLKDFFNGKEPNRGVHPDEAVAYGAAVQGGIFTNEEGTDTLVLLDIAPLTLGIETVGGVMTALIPRGTFVPTKKSQVFSTYQDNQDRVSIQIYEGERSMTKDNNLLGKFDLSGIPPAQRGVPQIEVTFEMDVNGILHVSAEDKASGSKESITITNDKERLSQADIDRMVKEAADAADEDKAAKERVEAKNTLENYIYQIKNTIGDKDKIGGKIESDDKETIETAISDALSWLDVNSSAEKEEFDEQYKILEKIVQPIFSKLYGAAGGSPNGAGEDMPNHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein 2, BiP 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RL36_PSYCK
Sequence: MKVQASVKKICGSCKVVRRKGRVHIICTAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: FABZ_YERE8
Sequence: MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPATAVVTKSEVTKPDVKES
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SULDN
Sequence: MSIDNSLKAFKEAQNLIPGGVNSPVRAFKSVGGTPLFIANGSGAYLTDIDGNRYVDFVQSWGPLLFGHRDESIESAVIEAVKHGLSFGAPTQAESDLAALVISMFDSIEKIRFVSSGTEAVMSAIRLARGYTNCDDIVKFTGCYHGHSDSLLVQAGSGAATFGNPSSPGVPADFTKHTLLAEYNNIESVKKCFSDSKDVACVIIEPIAGNMGLVPADKEFLRELRELCDANGALLIFDEVMSGFRASVHGAESITGVKPDIVTLGKVIGGGMPVGAFGARAEIMAKLSPEGPVYQAGTLSGNPVAMAAGLAAITKLKQNGQIISVLNSRATRLVEGMQEAAKTYGIAMQIDTRGSMFGFFFNEKPVKNFADACNSDEKLFALFHSKMLKEGFYFACSLYETGFISTAITDEMIEDTIKASAKVFKEITNV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXY_YERPA
Sequence: MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLDKALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: NANK_SALPK
Sequence: MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNLGGLLHFPLVQTLEAIAGLPTLAVNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLADPHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKATTDCQCVVIGGSVGLAEGYLEQVRAFLMQEPAPYHVALSAARYRHDAGLLGAALLAQGDTL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: FADI_SHESW
Sequence: MSDRQQVTNAKGERIAIVAGLRTPFAKQATAFHGVSALDMGKMVVNELLARSELDPKLIEQLVYGQVVQMPAAPNIAREIVLGTGMNVSTDAYSVTRACATSFQSTVNVAESIMTGNIDIGIAGGADSSSVLPIGVSKKLAHALVDLNKARSFGQKLQIFRRLGLKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHTLASETWASGHLRDEVMVAHIPPYKQFIDRDNNIRENSVLESYAKLRPAFDKQHGTVTAANSTPLTDGASAIILMSEGRAKALGYQPIGYIKSYAFSAIDVWQDMLMGPSYATPLALKRAGMELEDLTLIEMHEAFAAQTLANMQMFASKKFAEEKLGRNRPIGEIDMSKFNVLGGSLAYGHPFAATGTRLITQVCRELKRRGGGTGLTTACAAGGLGVAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDH4_SHV2C
Sequence: MLKWSTLCFRFVRAMQQALFLTIFFHMQIFCIAFTYNSTFKCSLITTSSLTCYKVLSTLYTQNSSKVYSTESTLYLFLNLSSTGF
What are the official names of this protein?
Uncharacterized 9.9 kDa protein in DHFR 3'region, ORF4.
Protein: Y1003_PROMH
Sequence: MYPVDLHAHTIASTHAYSTVSEYFQQAKKKGIKLFAITDHGPDMDDAPHEWHFSNLPVIPRMVDGVGILYGIEANIKNIKGEIDCTEKMSKKLDIVLAGFHDPVMGSLGMVDNTKALIATISSGLVQVITHPGNPKYPIDIKEVAKVAAEFNVALEMNNSSFIHSRVGSEKNCIEIAKAVLDAGGLIALGSDSHIASSLGNFERVLEVLAEIQFPQQKILNTSPRKVLDFLQAHGKKEITAFQHL
What are the official names of this protein?
Probable phosphatase PMI1003.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: BPT_BURTA
Sequence: MTHPTELPLSPLSALQFYATAPYPCSYLDGRIARSQVATPSHLINSDIYTELVKAGFRRSGVFTYRPYCDGCRACVPVRVPVDAFAPNRAQRRAWKRHRALVATVSPLHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFRDLDTPKDGASALRMVSMIDILGDGLSSVYTFFDPDESHASYGTYNILWQIEQAKSLRLPYVYLGYWIRESPKMAYKANFHPLEGLVDGRWKVLDPTLVDLPPVDAALARAPLPGGHSGTR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_MARMS
Sequence: MKESIKLKLESLSDRYDELAALLGVAEVIMDQDLFRAYSKEYAELEPVVKCFNEFQQIDENIAEAELMMTDADPDIKEMGVEEYKAGLAQKEELQLVLQKLLLPKDPNDSRNVFLEVRAGTGGDEASIFSGDLFRMYSRYAETQRWKVEIVSASDGEHGGYKEVIARIVGEGAYSKLKFESGAHRVQRVPATESQGRIHTSACTVAVMPEMDEVDDIIINKSDLRIDTFRASGAGGQHVNKTDSAIRLTHIPTGVVVECQEERSQHKNRAKAMSLLASRLQAAELEKAASEQSETRKSLVGSGDRSERIRTYNYPQGRVTDHRINLTLYKLDEIVAGELDSLINPLVNEFQAEQLAALSGDN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX2M4_LYCSI
Sequence: MIKYVLISALLVVAVYSFTIEDNEDALLEEAEDELDTEEERRMALPPGAVCNGHKSDCQCFGAKYECSCPFLWRFRRSAKCHCKKGWAWTAVKKRSCHNRYQWSG
What is the function of this protein?
Insecticidal to house crickets.  It induces an excitatory slow-onset impact that leads to irreversible spastic paralysis.  It also modifies human voltage-gated potassium channel Kv1. 5/KCNA5.  Most likely, it binds to the voltage-sensing domain of the channel, suggesting it does not block the pore but prevents its opening at physiological membrane potentials.  The recombinant peptide binds to the channel in an irreversible manner and slows down the hKv1. 5 current activation kinetics.  It is not toxic to mice, when intracranially injected (at 0. 5 ug/g mouse).
What are the official names of this protein?
U2-lycotoxin-Ls1d, U2-LCTX-Ls1d, Toxin LSTX-M4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 01 (type I omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_BURP0
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSETDKARLLDHLRKSHGATDGDKRKITLTRRHTSEIKQADATGKARTIQVEVRKKRTFVKRDDVSETGADQAHAQTDEQAEAELKRREEEARREAELLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAAQAEAAQQAAAAREQAQRAQSEPAEQSAQDEARAAAERAAQREAAKKAEDAAREAADKARAEQEEIRKRREAAEAEARAIREMMNTPRRAQVKAVEPPKPAEPPAAKTAEAKGTLHKPAKPAGEAAAARPAAKKPASGAPAPAAAPAGDRTKKPGTGKSGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGKHQDSASSFQAPTEPIVREVHVPETISVADLAHKMSIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGEIGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVESPAKGIVIEAKLDKGKGPVATVLVQSGTLSRGDVVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPGAGEEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGVVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVKQGFECGMSLKNFNDIVEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGBA_HUMAN
Sequence: MPRGQKSKLRAREKRRQARGGLEDLIDALDILEEEEESPPSASACLKDVFQSSLDGASNNPHGLREAQSTSTSATAASHTRHPEGVNDQMEERPICTQDLEATDSFPRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHLELIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCVAEEEVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEEERARARVAAKARVSATAGARSKVKSSKSSQLQ
What are the official names of this protein?
Melanoma-associated antigen B10, MAGE-B10 antigen.
Protein: VDHAP_CHICK
Sequence: MTLERLWQVLDPLWADPRVLSALFCGSAMAVVLLKRLGHRRIQQKMEEARRARDLALERMEKAARRFKQENPGTQTAHILSLTMVELAEKLKEGSLSPESVLYSYMGKALEVNREVNCVIDFIHGCEDQLQKVKQQKEKGLLYGIPVSIKDHIDCKGHVSSAGLVKFLGQVKEEDSVIVQVLKSQGAIPFVKTNIPQTMINYDCSNLIFGQTLNPLNHQKTPGGSSGGEGALIAGGGSLLGIGSDVAGSIRLPSSFCGLCGLKPTGFRISKLGVISPITGMNSVIGMLGPIARDVDSLALCMKALLCEEMFRLDPTVPPIPFDEEVYTSSKPLRIGYYEEDGYFQPSPSMKRAVQQTRKLLQEAGHTIVPFAPPKIDYVVDELFTRGIFSDGAAHLVDSFKGDIVDPNLKSQFNTYKLPALVKRILAIILKPIYPRIARDLSALCGVGSAKNLWDQHTAVGLPH
What is the function of this protein?
May have a vitamin D3 hydroxylase regulatory function.
What are the official names of this protein?
Vitamin D3 hydroxylase-associated protein, VDHAP.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: ATP6_SHIDS
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINIDSMFFSVGLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRD_HALHL
Sequence: MYALIRQLLFRLEPEQAHRVSMQLARLGLRIAAVPGVRSLPAVPRRVMGIDFPNPVGLAAGFDKDGEYMDVLEQLGFGFLELGTVTPRAQPGNPQPRVFRIPEHEALINRMGFNNQGAEPLVRRLEVSRHRGVVGINIGKNRDTPPERAVEDYAQALGMVYGVADYVAVNLSSPNTPGLRDLQHEGALRNLIDRLQTERKRLAELHDKRVPLVVKIAPDWEAGELDATLDILLERRVDGIVATNTTLGRTGVEQTPQARESGGLSGAPLREQAEWVLEQVAARRDRRTALIAAGGIMSGEDVTRRLDLGADLVQLYTGMIYRGPGLVQEAVRAAARHAGQPA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ITM2B_RAT
Sequence: MVKVTFNSALAQKEAKKDEPKSSEEALIAPPDAVAVDCKDPDDVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGLKYIKDDVILSEPSADAPAARYQTIEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENVDHLGFFIYRLCHDKETYKLQRRETIRGIQKREASNCFTIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: FTHS_STAA1
Sequence: MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDINKITPRENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRRIEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVASEIMAILCLSRSIKDLKDKISRITIGYTRDRKPVTVADLKVQGALAMILKDAIKPNLVQSIEGTPALVHGGPFANIAHGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKAREAGFDLAAVVVVATIRALKMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYVKSWAKENNVRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKIVTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEITIRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.