PharMolix/UniProtQA huggingface dataset:
Protein: NTPPB_IDILO
Sequence: MTLPLILGSGSKYRREILDRLHLNYDVVKPDIDESAISSESPQQLVGRLAEAKARAVEKRMTYDNAIIIGSDQVAVCDGNILGKPGNRENAVRQLSSFIGKTVTFYTGLAVFNTEAQQCEVRVEPFEVEFRQLTAEEIERYVELENPFDCAGSFKSEGLGISLFSGLKGNDPNTLIGLPAIALLDMLRTHGINPLNKD
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGT1_YEAS2
Sequence: MNELNTVSTNSSDSTKDGGTSNSPDDMDSAAAASHAIKKRTKASRACDQCRKKKIKCDYKDEKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNEIQDHNNSRSYNTFDNSNNTLNNNTGNSGDNGINSNTVPSTPSRSNSVLLPPLTQYIPQAGGIPPSFQNPAIQSTMPAGNIGQQQFWKVPYHEFQHQRKGSIDSLQSDISVRTLNPNEQLSYNTVQQSPITNKHTNDSGNANGSVTGSGSASGSGGYWSFIRTSGLLAPTDDHNGEQTRRSSSIPSLLRNTSNSLLLGGQPQLPPPQQQSQPQAHQQKLQQGQNLYSYSQFSQQQPYNPSISSFGQFAANGFHSRQGSVASEAMSPSAPAMFTSTSTNPVNVAQQTQRPQGQQVPQFSSELDGNKRRQSAPVSVTLSTDRLNGNENNNGEINNNNGSNNSGSSKDTSQHSQESVTTPVALEASSPGSTPQRSTKKRRKSYVSKKTKPKRDSSISITSKDSAHPMTTSSTIAYGQISDVDLIDTYYEFIHVGFPIIPLNKTTLTSDLLLVNTQPISNIHEVNSYVILWFRNSLELLVRVALKQKPGGKFFDNIVGVALSPSNDNNKAGFTTATARDDAEKTRRDSHNEVQDTLEVQSVFIAALNECFQKIVDIHPKFRENNDQISPKIKVIYLSTFILLNYILAFVGYDNSFVLGMSVTIFNEFKLYKLLLFPEPDINDVKPPVDEEVSTGNGNTKTSEFEIGSESAGHMNPSNSPNSMDENISHYSVLFKRLYVLLSVFDSLQSCAFGGPKLLNISIQGSTERFFSNDLGSKWCLEQSQLRLKSVLQSLKLGELMSELTRNRISMNGNRKPGFDITNSSSLLSEYVETQPLSVAQLFCKLLIGKHNFINCLLSLYDSEAGVYSDLTLDLSSKIADSLCSLISIILQVLTLILRLNPTNSIDFNYRPPNPPANNPTVQEGPSAMGSSPVAGNLSAAPPSEGNPDFYKKLLGLKQDTGTILSDLCRGIISPFAIAILHEVYNITELVKQMPTSLISIMMTATTTQNTQDTKKSQDLVMKLSNSMNEVVQITSVLTMIKPFKIFEHELNKPIMSLTGGLSSTTRNDVMWPKSGQGLRESSVMKTLLDERRTSGTQPTTAPVAAEEPRLENVALENFVSIGWKLLDDSELGWY
What is the function of this protein?
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose.  In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator.  In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription.  Binds the consensus binding site sequence 5'-CGGANNA-3', of which multiple copies are present in all HXT promoters regulated by RGT1 (By similarity).
What are the official names of this protein?
Glucose transport transcription regulator RGT1, Restores glucose transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NCED3_ARATH
Sequence: MASFTATAAVSGRWLGGNHTQPPLSSSQSSDLSYCSSLPMASRVTRKLNVSSALHTPPALHFPKQSSNSPAIVVKPKAKESNTKQMNLFQRAAAAALDAAEGFLVSHEKLHPLPKTADPSVQIAGNFAPVNEQPVRRNLPVVGKLPDSIKGVYVRNGANPLHEPVTGHHFFDGDGMVHAVKFEHGSASYACRFTQTNRFVQERQLGRPVFPKAIGELHGHTGIARLMLFYARAAAGIVDPAHGTGVANAGLVYFNGRLLAMSEDDLPYQVQITPNGDLKTVGRFDFDGQLESTMIAHPKVDPESGELFALSYDVVSKPYLKYFRFSPDGTKSPDVEIQLDQPTMMHDFAITENFVVVPDQQVVFKLPEMIRGGSPVVYDKNKVARFGILDKYAEDSSNIKWIDAPDCFCFHLWNAWEEPETDEVVVIGSCMTPPDSIFNESDENLKSVLSEIRLNLKTGESTRRPIISNEDQQVNLEAGMVNRNMLGRKTKFAYLALAEPWPKVSGFAKVDLTTGEVKKHLYGDNRYGGEPLFLPGEGGEEDEGYILCFVHDEKTWKSELQIVNAVSLEVEATVKLPSRVPYGFHGTFIGADDLAKQVV
What is the function of this protein?
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity.  Catalyzes the first step of abscisic-acid biosynthesis from carotenoids, in response to water stress.
What are the official names of this protein?
9-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic, AtNCED3, Protein SALT TOLERANT 1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Partially bound to the thylakoid.
Protein: ATPL_STRZT
Sequence: MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CITX_SHIB3
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: G6PI_BURO0
Sequence: MTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADFSKNRIDDETLRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALHHVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVARGCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVDALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESVDPAKHDSSTTALIERARAALKR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
Protein: LPMG_ECOL5
Sequence: MEPDPTPLPRRRLKLFR
What is the function of this protein?
Makes mgtA transcription sensitive to intracellular proline levels.  Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene (By similarity).
What are the official names of this protein?
mgtA leader peptide, Regulatory leader peptide for mgtA.
What is the protein family that this protein belongs to?
Belongs to the MgtL family.
Protein: PRS10_CAEEL
Sequence: MLLLQFSNMVEPTGPAIVEDERTKALNSYRRKLAECRDIEQKLKDLRKKESEMTKQFDKSENDIKSLQSVGQIVGEVLKQLSEEKFIVKATNGPRYVVGCRRSINKEELKQGTRVSLDMTTLTIMRQLPREVDPLVYKMSHEDPGNISYSDVGGLAEQIRELREVVELPLINPELFKRVGITPPKGCLLFGPPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARMIREMFNYARDHQPCIVFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDSLGKVKVIMATNRPDTLDPALLRPGRLDRKIEIGLPNEQSRLEILKIHSNKITKHGEIDFEAVVKLSDGFSAADLRNVCTEAGMFAIRAEREFVIDEDFMKAVRKVGDAKRLETKLDYKPV
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
Probable 26S proteasome regulatory subunit 10B, 26S proteasome AAA-ATPase subunit rpt-4, Proteasome regulatory particle ATPase-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CODY_CLOBA
Sequence: MSSLLSKTRRLNKILQKTGTEPVAFQDICTLLSEVLECNAYIVSKRGKVLGYTFSPGFECEAMKKKVIEDKKFPEDYNLTLLESNETLANLSNQGRCVFAEIGDCKTKDKISTIIPIIGSRERLGTLILARFGKEFTDDDLVLVEYSATIVGMEMLRALQEDLADQTRKKAVVQLAIGTLSYSELEAVEHIFEELNGNEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTYIRVLNEKLLDELKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_THEMA
Sequence: MRAVVQRVSEAKVVVGEETVGAIKKGLLVFVGVGKNDTEEDCEWLADKVSGLRIFEDEDGKMNLSVKDINGEVLVVSQFTLYGDCRRGKRPSFTEAAPPDKGKALYEKFVELLRKKGLKVETGKFRAHMHVHLVNDGPVTILLDSSKLF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_ECO27
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: KATG_JANSC
Sequence: MMDGAQTNSGGCPVMHGGGSRPMGATANQHWWPNQLNLKPLSANSEKLDPMGEGFDYAEEFQKLDMAAVKADIANCLKDSQDWWPADYGHYGPLMIRLAWHSAGTYRTYDGRGGAGTGTQRFAPLNSWPDNGNLDKARRILWPIKEKYGKSLSWADLLILVGNVALEDMGFETFGFAGGRADVWEPEEDIYWGPETEWLATSDMENTRYGEGRDLHNPLAAVQMGLIYVNPQGPDGNPDPLASAFDIRDTFARMAMNDEETVALVAGGHTFGKAHGAGDPDLVGAEPEGADVAEMGLGWKNGFESGKGVHSTTSGVEGPWTPTPTQWDMSYFDVLFGHEWELTKSPAGAHQWRPVDHENDQAPQVDGNGTVPIMMTTADMAMRMDPAYEKISRDFHANPDKFADAFARAWYKLTHRDMGPIQRYLGNDVPSEELLWQDPVPMPQGPQVNDDEQAELKAAVAATGLTAAELVRVAWGSAASYRDSDKRGGANGARIRLQPARGWTVNNPEELDKVLPVLDSIADAFNGRGGTQITMADMIVLAGGVGVEMAAREAGHNIHVPFTPGRGDATQEQTDVDSYDVLEPTSDGFRNYHATFSLREPAEMLVDKAALLGLTAPEMTVLVGGLRAIGATHGGARHGVLTETPGALNNAFFKNVLSMDTVWNQTDSAILEGKDRASGQVKWTATIVDLVFGSNSQLRAVAEVYASADAEAKMVDDFVAAWVKVMENDRFDLHR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RPOC_CLOPS
Sequence: MFELNNFDALQIGLASPEQIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPIKDWECHCGKYKRVRYKGIVCDRCGVEVTKSKVRRERMAHIELAAPVSHIWYFKGIPSRMGLILDMSPRALEKVLYFASYIVIDPKETSLLKKQLLNEKEYREACDKYGEESFVAGMGAEAIKTLLSEIDLERTAAELKEELKQSTGQKKVRIIRRLEVVESFKSSGNKPEWMVVDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKMYQCGLPKEMALELFKPFVMKKLVEDGVAHNIKSAKRMVERVMPQVWDVLEEVIADHPVLLNRAPTLHRLGIQAFQPVLVEGRAIKLHPLVCTAYNADFDGDQMAVHVPLSVEAQAEARFLMLAAGNIMKPSDGRPVCVPTQDMVLGSYYLTMDKDGAKGEGKYFASFDEVIMAYQLKEVDIHAKINVKVTKEIDGELKSGIIKTTPGFIIFNECIPQDLGFVNRENPEEMFNLEIDFLITKKSLGKIIDKCYLKHGPTKTSIMLDNIKATGYHYSSIGAVTVAASDMIVPQKKYELLKEADETVDKIEKMYRRGLISEDERYERVIEKWTETTEEVADTLMNSLDKFNPIFMMADSGARGSKSQIKQLAGMRGLMASPSGKIIELPIRASFREGLDVLEYFISTHGARKGNADTALKTADSGYLTRRLVDVSQDVIVREHDCGTQNGIYVEEIKEGSEVVEQLAERLTGRYTAEDVFHPETGELLAAKDTYMDPILAEKIADTGIQKVKIRSVFTCDSKVGVCTKCYGMNMATSYKINIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGADITQGLPRVEELFEARKPKGLAIVSEVAGTVRIEETKKKRTVYVVTDSGEEYSYDIPFGSRLKVKDGIAIGAGDEITEGSVNPHDIMSIKGVDGAREYLLSEVQKVYRLQGVDINDKHLEVVVRQMTRKIKVTEQGDTNLLPGVMIDMFDFRAENERVESFGGEKAQGDIVLLGITKAALATDSFLSAASFQETTRVLTDAAIKGKIDPLVGLKENVIIGKLIPAGTGMMKYRSLKLNTENSNQETETIIEIEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: GPSB_BACC1
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: THIQ_AGRFC
Sequence: MTGDDFAVALDKIRLRLGTQNFDLDCTFPQGQVTAVVGASGSGKSTLLNLVAGFEVPDFGRVVIHGQDMAASDPSERPVSSIFQDNNLFAHLDIFTNVALGVSPGLKLRAEDRQRIEVALARVGLAGFDKRLPGTLSGGERQRAALARALVRQKPVMLLDEPFAALDPGLRAGMTALLLDLHAETKNTVIIVTHHPDDIKKLAQRVVFLDRGRVVYAGSTADFFATQNVKAVDSFLNG
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_NITSB
Sequence: MARYRGPVEKIERRLGVSLALKGERRLAGKSALEKRPYPPGQHGQRRSKISEYGLQLREKQKAKFMYGVAEKQFRNLFKEANRMEGNTGENLIKLLERRLDNVVYRMGFATTRRFARQLVNHGHVLVDGKRVNIPSFRVKPGQKIEIREKSKNNPQIQRSLELTNQTGIVPWVDVDKEKVFGIFTRIPEREEIDIPVEERLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: VT3C_SHEVK
Sequence: MLCIFYIARLCNLIIYSLYSLLMFPMQKLISFMFGNLNPFDSVLDKDEKIQDNINTNHKPIESKEINNDLPLTVLDKKDTSDINIRNDNGVFDFIKIPNPFKKHYEYYCNQNTIKEPPRKGLVERMMNMVE
What are the official names of this protein?
T3C protein.
Protein: RL21_SACEN
Sequence: MYAIVKTGGKQYKVAVGDVVEVEKLEGEPGSEVTFPALLLVDGSDVTADADALAKVSVTGKLVEQTKGPKIRIHKFKNKTGYHKRQGHRQKLTRVEVTGITK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HFQ_NITWN
Sequence: MAIDRAQNLQDTFLNHVRKTKTPLTIFLVNGVKLQGIVTWFDNFCLLLRRDGHSQLVYKHAISTIMPGAPIQLFEGGEDAPL
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: YIDD_BURVG
Sequence: MKTVLIALLRFYKVAVSPMLGDRCRFYPSCSDYAREAIQYHGAARGTYLAVRRVCRCHPFSAGGIDLVPPPNSDIRARGEADARSHRL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RF1_SYNY3
Sequence: MAETYLLDKLASVEQTYQELTRMLADPDIATNPDELQRVAKARSSLEETVDTYETWKRSQEDLKGARQIVKESGNDPEMREMAQLEVEELENAIGELEKRLTILLLPKDPNDEKNIMLEIRAGTGGDEASIWAGDLVRMYTRYAESQGWKVSLLSESLADMGGFKEAILEVKGDRVYSQLKFEAGVHRVQRVPVTEAGGRVHTSTATVAIMPEVDDVEVKIDPKDIEMSTARSGGAGGQNVNKVETAVDLFHKPTGIRIFCTEERSQLQNRERAMQILRAKLYDMMLQEQNDAISSNRRSQVGTGSRSEKIRTYNYKDNRVTDHRLGRNFDLNTALEGEIHTIIESCISQDQQERLAELAEATNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA2_STAA8
Sequence: MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLADWHIGLPEIVQLQYDFEQKYQTKLKDIALTEEAFVSLYKEWQHEK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYR5_ASPFU
Sequence: MRVLIIGGSIAGLTLAHCLEKAKIDYVLLEKKEEIAPQEGASIGILPNGGRIMEQLGLYHQIEQLIEPLARAHVTYPDGFHFTSQYPALLQQRFGYPLAFLDRQKLLQILAAGPVQSGRVKLGHQVVNIESTPDGVTVRTSHGHVYQGDLVVGADGVHSRVRAEMWRLATASQGEIFRSEYNKLTIDYACIFGISSPVDQLEPGEQITCYNDGWSILSVIGQNGRVFWFLFIKLDKESVYDGSRKNGPRFSPADARAHCERLAHEPVWNGVKFGHVWAQCEVFQMTPLEEGLFSKWYWRNIVCIGDSMHKFAPHIGQGANCAIEDAAQLSNRLQAWLYGCGPNDPPTASDLSEILAGFVEDRLRRLGPVAVAARSAMRLHARQGVKNWILGRYLLPYAGDKPADWASQGIAGGGVTLDFVEPPERSGPGWVQFSQPRKRPTFPLTVAGLCLVAIVIRMLHSTLTV
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of pyripyropene A, a specific human acyl-coenzyme A:cholesterol acyltransferase 2 inhibitor (PubMed:20861902).  The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase pyr1 (PubMed:20861902).  Nicotinyl-CoA is then a substrate of polyketide synthase pyr2 to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase pyr6 to yield farnesyl-HPPO (PubMed:20861902).  The next steps consist of an epoxidation of farnesyl-HPPO to epoxyfarnesyl-HPPO by FAD-dependent monooxygenase pyr5 and a cyclization of the terpenoid portion by the terpene cyclase pyr4 to yield deacetyl-pyripyropene E (PubMed:20861902).  The 2 cytochrome P450 monooxygenases pyr3 and pyr9, and the 2 acetyltransferases pyr7 and pyr8 are involved in the conversion of deacetyl-pyripyropene E into pyripyropene A through several cycles of oxidation and acetylation steps (PubMed:20861902).  Pyr7 acetylates deacetyl-pyripyropene E to pyripyropene E which is oxidized to 11-deacetyl-pyripyropene O by pyr3, which is in turn acetylated into pyripyropene O by pyr8 (PubMed:21224862, PubMed:26019565).  Pyripyropene O is then oxidized to deacetyl-pyripyropene A by pyr9 (PubMed:21224862).  Deacetyl-pyripyropene A is finally acetylated to pyripyropene A by pyr8 (PubMed:26019565).
What are the official names of this protein?
FAD-dependent monooxygenase pyr5, Pyripyropene synthesis protein 5.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PUB12_ARATH
Sequence: MAKSEKHKLAQTLIDSINEIASISDSVTPMKKHCANLSRRLSLLLPMLEEIRDNQESSSEVVNALLSVKQSLLHAKDLLSFVSHVSKIYLVLERDQVMVKFQKVTSLLEQALSIIPYENLEISDELKEQVELVLVQLRRSLGKRGGDVYDDELYKDVLSLYSGRGSVMESDMVRRVAEKLQLMTITDLTQESLALLDMVSSSGGDDPGESFEKMSMVLKKIKDFVQTYNPNLDDAPLRLKSSLPKSRDDDRDMLIPPEEFRCPISLELMTDPVIVSSGQTYERECIKKWLEGGHLTCPKTQETLTSDIMTPNYVLRSLIAQWCESNGIEPPKRPNISQPSSKASSSSSAPDDEHNKIEELLLKLTSQQPEDRRSAAGEIRLLAKQNNHNRVAIAASGAIPLLVNLLTISNDSRTQEHAVTSILNLSICQENKGKIVYSSGAVPGIVHVLQKGSMEARENAAATLFSLSVIDENKVTIGAAGAIPPLVTLLSEGSQRGKKDAATALFNLCIFQGNKGKAVRAGLVPVLMRLLTEPESGMVDESLSILAILSSHPDGKSEVGAADAVPVLVDFIRSGSPRNKENSAAVLVHLCSWNQQHLIEAQKLGIMDLLIEMAENGTDRGKRKAAQLLNRFSRFNDQQKQHSGLGLEDQISLI
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 12, Plant U-box protein 12, RING-type E3 ubiquitin transferase PUB12.
Protein: SYK_TREPA
Sequence: MSICEKSLHWADKVAHKIIKERADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRIPDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQAILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVVFEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPNTEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVLAFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYAVARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SHEHH
Sequence: MAIGLIGRKVGMTRIFNEDGASVPVTVIEIAANRVTQVRTLDTDGYRALQVTTGTKKANRITKPEAGHFAKAGVEAGRGLWEMRLADGEGEGIEVGAELNVDIFADIAKVDVTGQSKGKGFQGGIKRWNFAMQDATHGNSLAHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLEVIRVDAERNLLLVKGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NAGS_DANRE
Sequence: MAKVNSGSSGCRAMVMAGQFWTKPFALSSQRSGPHRRSAAEVNRRMSSSRTAGHGSKTPLWSQQESYNHSSLGERSAWSNRTLIYRDVKAFLREIGGDPREARYWLTHFQRAGSTPAFAVLEVDPSVFDSHEMVQSLAFGLSFLQRMDMKLVVVMGLPAEITEDDHTRSATDSPLARTVMVKHCQALTEALQDNSANVMPFFSSEALLQLQDNPLDGSSSGPSVVVDSALLQWTLDCRVIPLVCPVGRDTTGRSSVLRSIQVTTAISQTLQPLKVIFLNSSGGIRNQNHKVLGLVSLPGDLPALSCAEWLNEVEQKRIGSIAELLNLLPVESSAVLTSANTLLTELFSHKGSGTLFKNGDPIRRYSSLEDIDVDRLLALINKSFEKNLREDYIASLEGRLHSVYLSEGYSAAAIITTEPVNSGTPYLDKFVVSSSKQGQGTGQILWECIRQDFSKLFWRSRTTNRINPWYFKHCDGSFVNGHWIVFWLGLSDIRESYELVEFAKSHPDSFCSLSTTETKPLQQHHGS
What is the function of this protein?
Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (cps1) activity.
What are the official names of this protein?
N-acetylglutamate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.