PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_BACMK
Sequence: MSHLLTMSELSEQEISEILKDAEDFANGKERKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLEVLDFSADASSVQKGETLYDTIRTLESIGTKAVVIRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLKIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEENTFGTYKSLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHEQHGLTVEREKRMKEGSIIMHPAPVNRDVEIASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELFV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FMT_SALG2
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTAAPEAQNEALVTHAEKLSKEEARIDWSLSAVQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNHLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: FBID_MYCTF
Sequence: MSGTPDDGDIGLIIAVKRLAAAKTRLAPVFSAQTRENVVLAMLVDTLTAAAGVGSLRSITVITPDEAAAAAAAGLGADVLADPTPEDDPDPLNTAITAAERVVAEGASNIVVLQGDLPALQTQELAEAISAARHHRRSFVADRLGTGTAVLCAFGTALHPRFGPDSSARHRRSGAVELTGAWPGLRCDVDTPADLTAARQLGVGPATARAVAHR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: LCAT_MOUSE
Sequence: MGLPGSPWQRVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNRLEAKLDKPDVVNWMCYRKTEDFFTIWLDFNLFLPLGVDCWIDNTRIVYNHSSGRVSNAPGVQIRVPGFGKTESVEYVDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPHQQDEYYKKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPILSNIKLKEEQRITTTSPWMLPAPHVWPEDHVFISTPNFNYTVQDFERFFTDLHFEEGWHMFLQSRDLLERLPAPGVEVYCLYGVGRPTPHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQPVHLLPMNETDHLNMVFSNKTLEHINAILLGAYRTPKSPAASPSPPPPE
What is the function of this protein?
Central enzyme in the extracellular metabolism of plasma lipoproteins.  Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs) (PubMed:19065001).  The cholesterol ester is then transported back to the liver.  Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels (PubMed:19065001).  Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins (PubMed:19065001).  Required for remodeling high-density lipoprotein particles into their spherical forms (PubMed:19065001).  Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines (PubMed:8820107).  Catalyzes the hydrolysis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor or PAF) to 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) (PubMed:10393212).  Also catalyzes the transfer of the acetate group from PAF to 1-hexadecanoyl-sn-glycero-3-phosphocholine forming lyso-PAF (By similarity).  Catalyzes the esterification of (24S)-hydroxycholesterol (24(S)OH-C), also known as cerebrosterol to produce 24(S)OH-C monoesters (By similarity).
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, 1-alkyl-2-acetylglycerophosphocholine esterase, Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, Platelet-activating factor acetylhydrolase, PAF acetylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into blood plasma (PubMed:8820107). Produced in astrocytes and secreted into cerebral spinal fluid (CSF) (By similarity).
Protein: SEN15_MOUSE
Sequence: MEERSDSEPTPGCSGPGPAPVRDGGGAHTWAPEDAWMGTHPKYLEMMELDIGDATQVYIAFLVYLDLMESKSWHEVNCVGIPELQLICLLGTEIEGEGLQTVVPTPISASLSHNRIREILKASRKLQGDPELPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR
What is the function of this protein?
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen15, tRNA-intron endonuclease Sen15.
What is the protein family that this protein belongs to?
Belongs to the SEN15 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=May be transiently localized in the nucleolus.
Protein: VAV_RAT
Sequence: MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELLSVHTHFLKELKDALSGPGATMLYQVFIKYKERFLVYGRYCSQVESAIKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDTTEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVPPCGRQDFSGTMKKDKLHRRAQDKKRNELGLPKMEVCQEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHTWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSVHLWYAGPMERAGAEGILTNRSDGTYLVRQRVKDTAEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLPELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAINKPPVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC
What is the function of this protein?
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
What are the official names of this protein?
Proto-oncogene vav, p95.
Protein: GCS2_PSEE4
Sequence: MARPWTFGIEEEYLLADTTSGQVLASPSPAVTRRCREMLGATFAEEMFLSQIEVVSPVFDSLHQARSFLGENRQRLGEALGDFGVGLYGAASHPCAQWLRQHPRGTAHFRQLFDDYRLVARRSLVNGLHVHVGVPAGTDRMQLINRVLYWLPLFLVLSTSSPLWGGQDTGYMSYRRVICGEWPHMGLPEPLADWHAYQRYRGLLQRTGALAEDGDFWWAIRPSRRFPTVELRICDGCPRLEDGLAIAGLYRHLVQHALARHDGMAVSREIRWITQENYWRAARYGRRGTFIGAVDQQPVSAEGWLAQLQSWLPADSAEAERSFMQARRILREGTSADRQREAYALARENGLAGREALRAVARQVMAEHFPGAGLPQGEIE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: KDSB_ALKEH
Sequence: MTTPFTVIIPARYASHRFPGKPLASLLGWPMIHHVCRRAEESGAARILVATDHREIAHACREEGREVVMTRHDHPSGTDRLAEVAERLGLDDDQIVVNLQGDEPLMPGRLVRQVALDLAAHRDAGIATLATLCHSLDEVRSPHAVKVVRDRQGYALYFSRAPIPWDRDGFSGAAGAARSPGQWLRHLGLYAYRVGFLRRYPALEAAPPEGLEALEQLRALWHGVRIHVGLAHQVPGPGVDTPQDLAQVERLLAEQGPPA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOD_PAENT
Sequence: MTDTYLHETLVFDNKLSYIDNQRDTDGPAILLLPGWCHDHRVYKYLIQELDADFRVIVPNWRGHGLSPCEVPDFGYQEQVKDALEILDQLGVETFLPVSHSHGGWVLVELLEQAGPERAPRGIIMDWLMWAPKPDFAKSLTLLKDPERWREGTHGLFDVWLDGHDEKRVRHHLLEEMADYGYDCWGRSGRVIEDAYGRNGSPMQMMANLTKTRPIRHIFSQPTEPEYEKINSDFAEQHPWFSYAKLGGPTHFPAIDVPDRAAVHIREFATAIRQGQ
What is the function of this protein?
Ring-cleaving dioxygenase involved in quinaldine degradation and utilization.
What are the official names of this protein?
1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: GREA_PSYCK
Sequence: MQRYPMTPQGHAALEAELKQLKSIDRPRITASIAEAREHGDLKENAEYHAAREQQGFCEARIRDIEAKLGGAQVIDPTTLPKDGRVIFGVSVVIENMDTEEEKQYKIVGDDEADFKAGKISVNSPIARGLIGKSEGDEARIETPKGVVEYEIMKVIYD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MCH_METBF
Sequence: MISVNEMGSNVIEEMLDWSEDLKTEVLKLNNGATVIDCGVKAEGGYEAGMYLARLCLADLADLKYTTFDLNGLKWPAIQVATDNPVIACMASQYAGWRISVGNYFGMGSGPARALGLKPKELYEEIGYEDDFEAAVLVMESDKLPDEKVVEFIAKHCSVDPENVMIAVAPTASIAGSVQISARVVETGIHKFESVGFDINCIKSGYGVAPIAPVVGKDVQCMGSTNDCVIYCGETNYTVRFDGELAELEEFVKKVPSTTSQDFGKPFYQTFKEANFDFFKVDAGMFAPARLTVNDLNSTKTISSGGLYPEILLQSFGIRNV
What is the function of this protein?
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_CHITR
Sequence: MSLTYMNMFMAFTISLLGLLMYRSHMMSSLLCLEGMMLSLFVMMTMTILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPRML_DANRE
Sequence: MNGTFFNHTVFTHGVLLNRSQELAGTLVDCCTGNGSEVTANDGGGSLVLAQDERKLFVTRVVQIAVLCVLSLTVMFGIFFLGCNLMIKSESMINFLVKDRRSSKDVEAVMIGLS
What are the official names of this protein?
Reprimo-like protein.
What is the protein family that this protein belongs to?
Belongs to the reprimo family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS16_CHLCV
Sequence: MALKIRLRQQGRRNHVVYRLVLADVESPRDGRYIELLGWYDPHSAVNYQLKGDRIFHWLSQGAELTEKAAVLIKQGAPGVYSELMAKQAARKAAVCQKRRAYRQRRSLKRAEAAKAAAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NRAMB_CAEEL
Sequence: MPGFQNANISDLAPPAREKTFDDTIAVKIPEDEKNTWFSWRKLWAFTGPGFLMSIAYLDPGNIESDLQAGAQAEYKLLWVLLVSHIVGMLLQRMSARLGVVSGKHMAEIAYDYYPLVPRIILWLMIEIAIVCSDMQEVIGTAIAIYLLSSGKIPLLVGVLITILDTFTFLFIDRYGIRKLEFIFVALISTMAISFGYEFVVMKPVLTKVLTGTVVPWCSGCGKEEIITAISIFGAVIMPHNFYLHSALVKSRKVDRSSKTRIAEANKYFSIESAFALSVSFFINLFVLSVFARGLYQKTNGDVNSMCLSHNDIPDSNVFPNNTSSVTVDLFQGGIYLGCQFGLFAMIIWAIGIFAAGQSSTMTGTYTGQFVMEGFVRISWPKWKRVLITRAVAITPTLILCIKAHGIKNLTGMNDFLNCVQMVQLPFALIPMITFTSSKRIMHNFRTSKPLQYFSIICGIITIGINVYFIFQYVTENFGTGWLIFVIIGPFTLLYIAFILYLAIYCLVACELMNDTVNLPGFDFHRTLELDAPWITETFVVNDVYF
What is the function of this protein?
Probable divalent metal ion transporter which regulates Mn(2+) uptake.
What are the official names of this protein?
NRAMP-like transporter smf-2, Divalent metal transporter smf-2.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=Predominantly localizes in cytoplasmic vesicles in epithelial cells.
Protein: EAT20_CAEEL
Sequence: MTTFCRVLLIFGIYVAVCCAQSVEDDVFHFTNPSQGNAVWILDESSLPWTGGYQFLRSISGMPTTLLSVVDSSTGVTLGQCVAPQDATGNFSKRWERFSWELTASGLDCTFEHGAAIRVEFDRTQNPRTFSIRIQSITGPACLRDVVVQTEQATGCPPHLSRNSFTANALNCSCPFLDAANEDSEIENEDVDMLANTPQFPLFKGIDPSVLGSANPPTLPPSPCANHECHNNGTCLVSQEGAATCLCRNGFTGDRCELDVCSSVPCQNGGVCRSNNGIAYCECPPAFTGLLCESAHTDESVAPICRPECSNGQCVFKDGQAQCECRQGFTGANCNVLDVCLGDAACSMFGPLAKCVLDDNMDKMSSLTLINGTYDCLCPHPIHGQFVDCMQLHAPSATSVQPTEQVVINNVTPSFPVLEISKLPTGAPVTFTATSTTLMVTQPTVTVSPTHQVPSEPFVGFTVTRAPLRPLDIGSTTLPPPFNQHIITAGEPTWSSQQPHQPSEVPTQTTFIFPQTPETTTFAPTTGTQQPVHKFVSPSVPDENEEEEEEETTEETEETFPTPSTMQVATNGQFTTETAFVTSTIPSTTTDMEETDEDEDMTEEVTDSSTQPSTTVFVQPTTTFTTEAPTTTMEEEEEMTTDQVEDIESEEIATTTTQTSLPFWMTTTNKQVVPDSPTPMVIMPHPQPDEKMETSTEGVVDEESDEERTTVPESNEEVVTKNAEATTPSDITHHHTSSGKQSSAAASWIIAIIALIVLGLLLLATSLFILRYIRQSRKLHGKYNPAREEHNLSAAYAMPMSHIAKEERLI
What is the function of this protein?
Regulates pharyngeal pumping during feeding.
What are the official names of this protein?
Abnormal pharyngeal pumping eat-20.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MURE_BLOFL
Sequence: MFKLKQLHELIVPWISGINVKIPYLTGLELDSRNINFGNLFIAIQGYNTDGRLHIDDAINNGAVAILSESYNKSTFFIKKIVNNVEVIPIIYFNQLNKCISNIAGRFYDHPSLCLKLIGVTGTNGKTTITHLLTNWTSLLGERSAVMGTLGNGVLSDINPSCCTTCSAIETQKILKQFVQSGVTFVAMEISSHGLDQYRVDSLYFDVAIFSNISNDHLDYHNNINQYRMAKWRLFNELRVKNYVINVDDCVGYRWLLSLSNAVAVTIKNNLPRSWSGRWIALVKADYYLYGTKIVFKSSWGNGFIHSQLLGEVNVSNILLALGALLIMGYSLKSLLYTGSKLYPVCGRLEVLSCLNHPTVIVDYAHTPDALKKILIFAKHLCNKGRLWCIFGCGGNRDRSKRSLMGVIANRYSDYVIITNDNPRVEDPKLIIDDIICKIRNSEKLKIIEDRVYAINMVVSKACSDDFVLILGKGHEKYQNIGLNYISHSDQDIVKSIFK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_XANCP
Sequence: MLPDLSAAPMQDRYGRPLRDLRLSVIEACNFRCGYCMPADRVPDDYGLDADQRLSFDQLETLVRAFVAVGVTKLRLTGGEPLLRKNLPVLIQRLAAIEGIEDLALTTNGALLARQAVALRQAGLRRITVSMDALEPALFRQMSGGRGEIDQVLAGIAAAEQAGFKRLKINCVVQRDVNEDQVLPLVEHFRGTGHVLRFIEFMDVGSCNGWRPEAVVTSAQLRDRIHARWPLAPLDANYTGEVAQRHAFADGLGEVGFVSSVSVPFCGDCQRARVSADGHLYTCLFASQGHDLKPALAEGEQGLATHLRQRWSVRADRYSEVRASTSRRRKPVEMFLIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TRMFO_STRZT
Sequence: MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGFSQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNDGDGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPSLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPDTTAIGSLAHYITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJO_BACSU
Sequence: MSYYNKRNQEPLPKEDVSTWECTKEDCNGWTRKNFASSDTPLCPLCGSKMVDGIRSLVNLQNNSQTKTS
What are the official names of this protein?
Uncharacterized protein YdjO.
Protein: TAL1_TAKRU
Sequence: MMEKRQPELCPGSPDAESGPGKREDAAIISRQNGCKEDEESKREEGDKEGGGRFKGDEETDDVPLQNSSNGTSISIIINGVTKETASHNALDLKREVPVIELSRRDAIKAVEQRTESHLVPITELRRPPQLPLPPQQRDDARMVQLSPNAFPVPARAMLYNLAQPLAAINSLGGESEQYSMYPSNRVKRRPAPYEVELDEAKIVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYISFLSNLLEDQDGGRNVSSTTDGETGLMVGAHEVGPQGGPHQDRVVGLARDDIMETMSPGSSCGSLPDGDADGSPESFMEDQDSPPAPRTLTASRGPPLHLTTRDLRRNGRPLDGSSRR
What is the function of this protein?
Transcription factor that plays a pivotal role in hemopoietic and endothelial development.
What are the official names of this protein?
T-cell acute lymphocytic leukemia protein 1, TAL-1, FrSCL, Stem cell protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: CU141_CONAA
Sequence: MLSVQLITPSSHGTAHLPRDDTDAAAGEILEFLCPFFCIGGIGDEYCDCQEKRDLDLFTDQ
What is the function of this protein?
Probable toxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Am14.1.
Protein: MSRP_BRUME
Sequence: MSSFKPSRFSTARLTGDAVTPKSIYLRRREFMIGLGAIAATGAASSAFADPLEAKTTAYKVDEKLTPQNAVTTYNNFYEFGTDKSDPSANSGSFKPLPWKLTVDGLVKQPKEFDVEELIAKMPLEERIYRMRCVEAWSMVIPWIGFPLSSLLSQVEPLGSAKYIAFTGVVRPDEMPGQTGLFQALNWPYVEGLRLDEAMHPLTILSVGLYGETLPNANGAPIRLVVPWKYGFKGIKAITRISFVEKQPPTSWNRQAANEYGFYANVNPAVDHPRWSQATERRIGEGGFFGSDRRPTLPFNGYGEEVASLYAGMDLKANY
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: RP54_RHIML
Sequence: MALSASLHLRQSQSLVMTPQLMQSIQLLQMNHLELTQFIAQEIEKNPLLEVQSPSDEASTAERGDSGPQPEEAGSEIDEGAGEGDVYDSATSRSGERLSDGLDSDFANVFPDDTTPQRADAPELLGQWKSMPGASDGESYDLDDFVASRKTLREALIEQLPFALESGSHRLIAQYLIDQLDDAGYLHADLAETAQRLASASEDVTRVLDVLQQFDPPGVFARTLGECLGLQLRARNRLDPAMEALVGNLDLLARRDFASLKKICGVDEEDLIDMFAEIRKLDPKPGTSFETGSFETIIPDAVVRTAPDGGWLVELNPDALPRVLVNHEYFAEISRSCRKSSGEQIFLNECLQNANWLTRSLDQRARTIMKVASEIVRQQDAFLMHGVGHLRPLNLRTVADAIKMHESTVSRVTSNKYMLTPRGLYELKYFFTASIGSAENGDAHSAESVRHRIRTMVNQESADAVLSDDDIVDILKKAGVDIARRTVAKYREAMHIPSCVQRRREKRALARVG
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of the nitrogen fixation genes (nif operon), glnA and dctA for dicarboxylate transport.  The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator proteins NifA, NtrC, or DctD for the expression of the regulated proteins.
What are the official names of this protein?
RNA polymerase sigma-54 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: Y3096_DROME
Sequence: MVKVQKPQPKSLNKSASIEGVVKKKGKPEKTKKLATDATLELASNKKAKNAAPVKKDAIKKEPEVSKKGAEKKQSKAAKRPLILAPPESPAAPAPAAKKSKAKPAASGAPVGKKIEAKKPLILAPPESPVPPKKQEKKTKAAPVKAKKEPAPAKKSVQDPVPSIKKVPAAKKSGQTAALTKKTAKTEKQAAPAKPAKAQPASQLQKKAKAVQKLSKPASPPKSKKALSKSKPGQAKGNAVNKEPAKSKKPVELTFELKAFDEKRFHEIVNENNVTKVCAALKSVVSEEVEKKKNTSIFSDYRYVLQVCSYKIPSCPKRMVKLNLKHSLVGKDDDVALIVPDLQRGAKFDYDPTKQHYEDMLREAGVKQRLTVVPFNQLRNEMGSFEAKRKFLNSYDYLLCDGRLSGQATAFLGKNTQKPRNVLHSLRLSKDNDKLPQEVTRALTRTAFRQLSKGDLIAVPVGNHEITAEQLAENILLVIKQLQEVYPGGLANIRSMYLKIDITGTSALPLYVSMCAPPEDVPYVVGPREQRMLKLKKQANEVLSKFAMTKDAEFIKLTSDQVKRKAQLRKEKAALLAADAAPKDNDGGDAAVPAKKARKESSSEGAKADAESDEEEEVEEAEDSAGESGDEDEEGHDGDDTDEDEDEDDDDDNEDGDDDEDEDDDEEDDDEEDDDDDDDEE
What are the official names of this protein?
Ribosomal L1 domain-containing protein CG13096.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family. Highly divergent.
Protein: HIS4_PSEA6
Sequence: MIIPAIDLIEGSVVRLYQGDYEQKTKYELDPIDVVNNYADQGAKWLHIVDLTGAKDTNKRQLKLIGDMVATGRMQFQAGGGIRSEQDVAQLLALGVKRVVIGSLAVKEPELVKGWVTKYGSEAIVLALDINIDEQGNKFIATHGWQENSGVSLEALLEDFLSVGAKHVLCTDISRDGTLQGANHQLYSEMAAKFPTIEWQASGGIGNLDDIAVLKPTHVSGVILGRALLEGKFTVEQAIECWQS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_METSB
Sequence: MTSSTLLETPAAAADHDCASAPRSLAGLTRDGLAAALLEIGAPERELRMRTAQLWHWIYHRGAGSFDDMLNVSKVLRTQLAEKFTLARPQIVTEQVSTDGTRKWLIRFAPSAESDRLAEVECVYIPDVDRGTLCVSSQVGCTLTCSFCHTGTQKFVRNLTAQEIIAQLIIARDRIGDFPGLAPRDGKGSNSGSRLVTNIVFMGMGEPLYNLDNVVDAVSVLSDGDGLSLSRRRITVSTAGVVPKLPELGEKTGAMLAISLHAVRDELRNTLVPLNKKYPIAALLQACRDYPGASNARRITFEYVMLKGINDSPSDARELVRLLKGIPAKINLIPFNPWPGTAYECSDDAVIEKFSDIVFNAGYASPVRTPRGRDILAACGQLKSETEKLRARALLVAGD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.