PharMolix/UniProtQA huggingface dataset:
Protein: PRS6B_BOVIN
Sequence: MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 6B, 26S proteasome AAA-ATPase subunit RPT3, Proteasome 26S subunit ATPase 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: E4F1_MOUSE
Sequence: MEGAMAVRVTAAHTAEARAEAGREAGEGGVAAAAALSSGGFLGLPAPFSEEDEDDVHRCGRCQVEFTALEDFVQHKIQKTCHRAPQEALPTTPAATALLDQEVVPTAAEGGPDEPITVAHIVVEATSLAEDISHAPDLVGSGHIKEVIVAAEAEPGDVEMAEAPGSPNHQELGLLGEGEQAHVKLLVNKEGRYVCMLCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCAKCGKSFRESGALTRHLKSLTPCTEKIRFSISKDTAVGKEEVPAGSSASTVGTVTSSVAGDPMETSPVIHLVTDAKGTVIHEVHVQMQELPLGMKALTPESPDSEELPCSSENSRENLLHQAMQNSGIVLERVAGEESALEPAPPSGSSPQCLGDGSPELPLLKVEQIETQVASEAATVPRTHPCPQCSETFPTAATLEAHKRGHIAPRPFTCTQCGKAFPKAYLLKKHQEVHVHERRFRCGDCGKLYKTIAHVRGHRRVHSDERPFPCPQCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLRTKGGCLLEVEELLVSEESPSAAATVLAEDPHTVLVEFSSVVADTQEYIIEATADDTETSEATEIIEGTQTEVDSHIMKVVQQIVHQAGAGHQIIVQNVTMDQETALGSEATAADTITIATPESLTEQVAMTLASAISEGTVLTARAGPNSTEQATVTMVSSEDIEILEHGGELVIASPEGQLEVQTVIV
What is the function of this protein?
May function as a transcriptional repressor.  May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53.  Functions in cell survival and proliferation through control of the cell cycle.  Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription.
What are the official names of this protein?
Transcription factor E4F1, E4F transcription factor 1, Putative E3 ubiquitin-protein ligase E4F1, RING-type E3 ubiquitin transferase E4F1, Transcription factor E4F, Transcription factor phi AP3, p120E4F.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=A small fraction is detected in the cytoplasm (By similarity). Excluded from the nucleolus where it is targeted upon CDKN2A overexpression. Localizes to the mitotic spindle during embryogenesis.
Protein: RENT1_DICDI
Sequence: MYGFNIGKAENAGLHLDNKKSENNNSSNNELHKVINTINNGFQFKDDDDEDNENNLNNESSSDEENQQQQNNNNNNNKNQFEDDDEDQEEEEYISGDDLNNNGQESDDYEEEEEDDDEDEEEEDEESKKLNYDSFFGANMSHNMDFLNSQNINSQIGLMDPHLHSSQLNFEEPQEEIELPAHACAYCATHELSTVVKCMHPSCGKWFCNGKGKTKSSHIITHLVKSKHKEVALHPESSFGDTTLECFNCGCKNIFLLGFITARTESVVVLLCRDPCASGPSKEVNWDMSSWQPLINGGEKAFCSWLVKTPSQVDSERSRQITIQQILRLEEFWKMDPEATLLDIEAPRSDDEKPASTQLAYKDAYEYREIISPLIELEAKHEKELRESLSQSGISIEWSQGINKRYTATFPFSRSDLEFKVVPGDELKLQFISSTGGVIEWEDTGRVIHIDDENLLSLETKSRCSFDSGPKGSYRMEMVWRSTSSERILSAMKSFAIKEQALSSYLYHALLGHPDIPPAPLDIQLPTNFHLKNLPRLNESQISAVNKVLTAPLSLIQGPPGTGKTVISSFIIHHLVKYVKGNDKVLVCTPSNVAIDQLTGKLHEIGLKVVRLSSKLREEVASPVEHLTLHKQVYKLDQMGDGELGKLRKLKEAFGSLSNEDEKRYIYLRRMMEMAILRKADVICATCVGAGDPRLSQFRFPHILIDESTQASEPECLIPLMMGAKQVILVGDHRQLGPVLLCKKVVDAGLSQSLFERLISLGHHPERLTIQYRMHPSLTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPKDPMFFFNCTGSEEISSSGTSFINTTEASICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQKSGKLNLELYKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFGLIILGNAKVLSKDPLWNSLISHFKNKNVLVEGSLANLKQSPVILQKPKKLYGQGKLPIPGQNSNSFNYDREHIDPNIGMNMVYGISNNNINNNSNNINNNNNNNINNNINNNNNQRFNTQDGRYSNSQTSSSSQTYYGSTNSSGNTINSNQNQFFNTPSSYSANTGSSYQYRFQQYQQLQQPQPQQQQQPQQQQQPQQQQQPQQPQQQQPQQQKQYQQQQQQQQQQQQQQQQQQQQQKQQPHQQYQSQKQQQQQQYQQPQQYQQQNQQYHQSQLPPKQYHNQRFNNNNNNNINNNNNNNNNNNNNNNNNNNNNNINNNNSKNQNQNQSPRRSPVVGTLQLHCKFDSQPNNNKHISDPNQPQISNPNMSIPLSQSLSFNDLSQEQFNKSNSRKD
What is the function of this protein?
RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs.  The formation of a surveillance complex is believed to activate NMD.
What are the official names of this protein?
Regulator of nonsense transcripts 1, Up-frameshift suppressor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_GLAP5
Sequence: MLRRDMNIADYDPELWQAIQGENRRQEEHIELIASENYASPRVMEAQGSQFTNKYAEGYPGKRYYGGCEYADIVEQLAIERAKELFGADYANVQPHSGSQANAAVYGALLMPGDTILGMSLAHGGHLTHGASVSFSGKVYHAEQYGITAEGVIDYDALRKQAHEVKPKMIVGGFSAYSQIVDWAKMREIADEVGAYLFVDMAHVAGLIAAGVYPSPLPHAHVVTTTTHKTLAGPRGGLILSNAKDEEIYKKLQNAVFPREQGGPLVHIIAAKAVCFKEALEPEYKVYQQQVVKNAKAMVEVFKQRGYNVVSNGTENHLFLVDLVSHGLTGKAADAALGKANITVNKNAVPNDPQKPFITSGIRVGTPSVTRRGFKEAEVRELAGWMCDVLDNIGKDNEAAVIEATKVKVLDICKRLPVYP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_WOLPM
Sequence: MAFNVTILSIFPEMFPGFLNYSLAGKALEKKIWNLEVINIRSFAKDKHSTVDDVPYGGGAGMVMRSDVVGDAVDSMLSVHKNTKFIYMTPSGTKFNQNIARELLEFPHITILCGRFEGIDQRIIDAYTPYELSIGDYILSGGEPAAMVVLDACIRLLPGVVNNTDSITEESFNYGGGVLEYPQYTRPEQWKGYKVPEVLLSGNHKKISDWRQKQSHVITKKRRPELLSGEINDKFT
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIO_MACFU
Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: AROA_STRGC
Sequence: MKLRTNAKGLRGSLRVPGDKSISHRSIIFGSLAKGVTKVHDILRGEDVLSTMQVFREMGVQIEDKGDLVEIHGCGFDGLQEPQRPLDMGNSGTSMRLIAGVLAGQNFSAQMVGDDSLSKRPMDRISLPLRRMGVEIAGQTERDLPPLTIHGNPNLKPIQYQLPIASAQVKSALIFAALQAQGESLIIEKDLTRNHTEDMLLQFGGQLKVDGKEIRVAGKQELQAQEVVVPGDISSAAFWLVAGLIVPSSKITLTNVGINETRTGILDVIQAMGGKLSVSEVDEVVKSATITVESSDLYGTEISGELIPRLIDELPIIALLATQAEGQTLIQDAEELKVKETDRIQVVADALNSMGADIQPTADGMIIQGKTSLKGASVHTYGDHRIGMMTAIAALLVKDGSVELSRAEAINTSYPDFFAHLEDLANV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTG_ANEVI
Sequence: FLLCFFLVADVSYGINKDCLLPMDVGRCRARHPRYYYNSSSKRCEMFNYGGCRGNANNFITKKECEKVCGVRSRDSPKEN
What is the function of this protein?
Serine protease inhibitor that inhibits both tissue and plasma kallikreins.  Has hemolytic activity.  Inhibits voltage-gated potassium channels (Kv).
What are the official names of this protein?
U-actitoxin-Avd3s, U-AITX-Avd3s, AsKC16.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CYSN_CHRVO
Sequence: MSHQSELIAGDILEYLSQHENKDMLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLAAIERDSKKYNTTDQDIDLALLVDGLQAEREQGITIDVAYRYFSTDKRKFIIADCPGHEQYTRNMATGASTSNLAIILIDARRGVQTQTRRHSYIVSLLGIRHVIVAVNKMDLVDYSEDVYNRIRDEYLTFAEHLDIPDIHFVPISALRGDNVVSRTEAAPWYQGATLMHLLETVQISHDAPLSAFRLPVQYVNRPNLDFRGFCGTIASGAVHPGDAVVALPSGKESRVKEIVTFDGSLSRAGAGQAVTLTLEDEIDISRGDMLVRADEARPHVSRSFDAHLVAMGEAPLRPGKEYGFKLAGKYVTGRIEAILHRTDVNTLQDSPADALALNEIGLCRISLNSPAAFDAYRDCRGSGSLILIDRLSNGTVAAGMIVAQSEEASPAALSPWALFEQELDQLLQRYFPQMTRAELARRLRDEL
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: MURD_CYTH3
Sequence: MSQKIVILGSGESGVGAALLSKAKGYDTFVSDSSMITEAFIAELQQAGIAFEQGVHSEEKILSAQLIVKSPGIPEKAPIMKLIRSKAIEVISEIEFAYRHIHPGAKFIAITGSNGKTTTTLLTHHILAQLGYSVGLGGNIGTSLARQIIHEKKDVYVLELSSFQLDDMYTFKADVAVLLNITPDHLDRYEYKFENYTASKFRIFQNLTPADYYITYSEDSVIESYKKDHPVDARYVPVSLKQLYSAGAYSDEKTIQIHALDDTVVTCNTEEFPLQGKHNYINIMAALNAAVSIGADIHKSIASIKSFRNAPHRLEFVGSIYGVKFVNDSKATNVDSVWYALDSMKTPVVLIVGGVDKGNDYSQIEALVKEKVHTVVALGKDNSKVLSGFASMVSEIKEAHSMVEAIRIAHDSAKKGDTVLLSPACASFDLFKNYEDRGTQFRNLVIELAG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGS2_RAT
Sequence: MKATLVLFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKSVFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHLDGNKIAKVDAASLKGMSNLSKLGLSFNSITVVENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYVQVVYLHNNNISEVGQHDFCLPSYQTRKTSYTAVSLYSNPVRYWQIHPHTFRCVFGRSTIQLGNYK
What is the function of this protein?
May affect the rate of fibrils formation (By similarity).  May be implicated in the dilatation of the rat cervix.
What are the official names of this protein?
Decorin, Bone proteoglycan II, Dermatan sulfate proteoglycan-II, DSPG, PG-S2, PG40.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: VP4_ROTSH
Sequence: MASLIYRQLLTNSYTVDLSDEIQEIGSTKSQNVTINPGPFAQTGYAPVNWGPGEINDSTTVEPLLDGPYQPTTFNPPVDYWMLLAPTTPGVIVEGTNNTDRWLATILIEPNVQSENRTYTIFGIQEQLTVSNTSQDQWKFIDVVKTTANGSIGQYGPLLSSPKLYAVMKHNEKLYTYEGQTPNARTAHYSTTNYDSVNMTAFCDFYIIPRSEESKCTEYINNGLPPIQNTRNVVPLSLTARDVIHYRAQANEDIVISKTSLWKEMQYNRDITIRFKFANTIIKSGGLGYKWSEISFKPANYQYTYTRDGEEVTAHTTCSVNGVNDFSFNGGYLPTDFVVSKFEVIKENSYVYIDYWDDSQAFRNVVYVRSLAANLNSVMCTGGSYNFSLPVGQWPVLTGGAVSLHSAGVTLSTQFTDFVSLNSLRFRFRLAVEEPHFKLTRTRLDRLYGLPAADPNNGKEYYEIAGRFSLISLVPSNDDYQTPIANSVTVRQDLERQLGELREEFNALSQEIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKKFKKSGLANSVSTLTDSLSDAASSISRGSSIRSIGSSASAWTDVSTQITDISSSVSSVSTQTSTISRRLRLKEMATQTEGMNFDDISAAVLKTKIDKSTQISPNTIPDIVTEASEKFIPNRAYRVINNDDVFEAGIDGKFFAYKVDTFEEIPFDVQKFADLVTDSPVISAIIDFKTLKNLNDNYGITKQQAFNLLRSDPRVLREFINQDNPIIRNRIEQLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers (PubMed:2153941). Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles. VP4 also seems to associates with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway (By similarity). SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: DLK1_MOUSE
Sequence: MIATGALLRVLLLLLAFGHSTYGAECDPPCDPQYGFCEADNVCRCHVGWEGPLCDKCVTAPGCVNGVCKEPWQCICKDGWDGKFCEIDVRACTSTPCANNGTCVDLEKGQYECSCTPGFSGKDCQHKAGPCVINGSPCQHGGACVDDEGQASHASCLCPPGFSGNFCEIVAATNSCTPNPCENDGVCTDIGGDFRCRCPAGFVDKTCSRPVSNCASGPCQNGGTCLQHTQVSFECLCKPPFMGPTCAKKRGASPVQVTHLPSGYGLTYRLTPGVHELPVQQPEQHILKVSMKELNKSTPLLTEGQAICFTILGVLTSLVVLGTVAIVFLNKCETWVSNLRYNHTFRKKKNLLLQYNSGEELAVNIIFPEKIDMTTFNKEAGDEEI
What is the function of this protein?
May have a role in neuroendocrine differentiation.  Inhibits adipocyte differentiation.
What are the official names of this protein?
Protein delta homolog 1, DLK-1, Adipocyte differentiation inhibitor protein, Preadipocyte factor 1, Pref-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: ADDB_STRPJ
Sequence: MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQGQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREELNR
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: NDHJ_PROMS
Sequence: MEKDSQATSSDTSIEKEGVISQSLSKDGIPNQSLSDDHIGIENISVQPSKLYEAVSALRNYGFNYLQCQGGYDEGPGKNLVSFYHFITVDDFQKIEKIKEVRLKVFLKRDSDLSIPSLYEIFKGSDWQERETFDMYGINFIDHPNPKRLLMPEDWRGWPLRKDYIQPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RIAD1_HUMAN
Sequence: METLPGLLQRPDPGALSAAQLEQLRKFKIQTRIANEKYLRTHKEVEWLISGFFREIFLKRPDNILEFAADYFTDPRLPNKIHMQLIKDKKAA
What are the official names of this protein?
RIIa domain-containing protein 1.
Protein: RBL_PHYPA
Sequence: MSPRPEIKAGVGFKAGVKDYRLTYYTPDYQTKDTDILAAFRMTPQPGVPAEECGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYAIEPVAGEENQYIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQGETGEIKGHYLNATAGTCEEMIKRAQFARELGMPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVLDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGERQVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIKFEFDTVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUS1_ARATH
Sequence: MSCSYLLSGDASVVASRRWSDVSSRQRLFLPRQSLRQPSGSSFSRCVRLVANVNDHFSKQSLATRNCLASVFSADLGGSNGNNDNGNGGGGGGDGGGDNSDDSSFDLRYLCFLLLGLSCFFHFRLSAASAIAKDQNSDSNGDAVKETVWEVRGSKRKRLVPDFVKDEFVSEESAFELSSSLTPENLLAQCRNLLTQFLLPEGFPNSVTSDYLDYSLWRGVQGIASQISGVLATQSLLYAVGLGKGAIPTAAAINWVLKDGIGYLSKIMLSKYGRHFDVHPKGWRLFADLLENAAFGMEMLTPVFPQFFVMIGAAAGAGRSAAALIQAATRSCFNAGFASQRNFAEVIAKGEAQGMVSKSVGILLGIVVANCIGTSTSLALAAFGVVTTIHMYTNLKSYQCIQLRTLNPYRASLVFSEYLISGQAPLIKEVNDEEPLFPTVRFSNMKSPEKLQDFVLSSEAKAAAADIEERLQLGSKLSDVIHNKEEAIALFDLYRNEGYILTEHKGRFCVMLKESSTPQDMLRSLFQVNYLYWLEKNAGIEPASTYSDCKPGGRLHISLDYVRREFEHAKEDSESVGWVTEGLIARPLPTRIRLGHDRELLLSSPNSS
What is the function of this protein?
Involved in a root UV-B sensing pathway and in the protection against the hypersensitivity to very low-fluence-rate (VLF) UV-B.  RSU1 and RUS2 are probably both negative modulators of the same UV-B perception pathway, which when overstimulated in the roots causes a block to postgermination development.  Required for polar auxin transport by maintaining the proper levels of auxin transporters AUX1 (AC Q96247) and PIN proteins on the plasma membrane.
What are the official names of this protein?
Protein root UVB sensitive 1, chloroplastic, Protein WEAK AUXIN RESPONSE 3.
What is the protein family that this protein belongs to?
Belongs to the RUS1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: MSLNL_HUMAN
Sequence: MAAAVTIPGPRIGALQSSGLTLLLSLAAHCSGPQAKVLSPGGLDASGANLWASANCSLLQGFWCQPASQLPRDQLSALIQRLALLQVPLQAWQLSCLANLASRCGLQDDFTLHPPNLLLFYNLSQVREADCRAFIRRAAQGDVELLSHLPDQRVALWRAAVACLVGAGLRLSASDQQLLGALVCDMDASSIGAADPHMLENLRRCPRLTAAQRIALNSLLAGGKTSLGPPGSWTLEGLQALGPLATYISPHLWAQVQEAVGLGFFRSVVASCQVGRLGQREARCFVTSFLESKTKPVSSRPRLSTGNITAATLRDDLFLVHYDCAELESCLDGCILRTNLDTLLQHLLPTECQHVVKAKLAQIYPQGLPEDQLRLITSLVYLYSRTEIGQWSITSQDTVMALLASDVALENQTEAVLQKFLEHNGTVSGALLLAIGGTRLCWMSPHQIQTIHPQELRLAGALDLSSCPQSRKDVLYTKAHETFGSSGTLAAYYRLMRPYLGGSPGGAQPPSPVPPGGAPVEELRHLAHANISMDIDTFTSLNPLELQSLDVGNVTALLGHNVGDLQKARSHPTVRAWLRSLNSSTLGQLGLDASPTSPTGPAHGTRGPPSTTHQVLHLVHTSGLPTNDAQASTSGSLWAPLGYLPLAMALPCSLLCLLHWGTCILVSVDSVASGWLGSQGSGAGKTEVLDSAGRPLGLTGQL
What is the function of this protein?
May play a role in cellular adhesion.
What are the official names of this protein?
Mesothelin-like protein, Pre-pro-megakaryocyte-potentiating-factor-like.
What is the protein family that this protein belongs to?
Belongs to the mesothelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.