PharMolix/UniProtQA huggingface dataset:
Protein: ABCC9_HUMAN
Sequence: MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLALFLYWVMAFITKTIKLVKYCQSGLDISNLRFCITGMMVILNGLLMAVEINVIRVRRYVFFMNPQKVKPPEDLQDLGVRFLQPFVNLLSKATYWWMNTLIISAHKKPIDLKAIGKLPIAMRAVTNYVCLKDAYEEQKKKVADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFAGPLCISGIVQRVNETQNGTNNTTGISETLSSKEFLENAYVLAVLLFLALILQRTFLQASYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQLMWFLFLCPNLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNEILKGIKLLKLYAWEHIFCKSVEETRMKELSSLKTFALYTSLSIFMNAAIPIAAVLATFVTHAYASGNNLKPAEAFASLSLFHILVTPLFLLSTVVRFAVKAIISVQKLNEFLLSDEIGDDSWRTGESSLPFESCKKHTGVQPKTINRKQPGRYHLDSYEQSTRRLRPAETEDIAIKVTNGYFSWGSGLATLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNVNESEPSFEATRSRNRYSVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTLVLVTHKLQYLTHADWIIAMKDGSVLREGTLKDIQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERKTLRRAMYSREAKAQMEDEDEEEEEEEDEDDNMSTVMRLRTKMPWKTCWRYLTSGGFFLLILMIFSKLLKHSVIVAIDYWLATWTSEYSINNTGKADQTYYVAGFSILCGAGIFLCLVTSLTVEWMGLTAAKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMISYATPVFLVALLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRFKQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGSSNSGLVGLGLLYALTITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYENNLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSSIMDAGLVLVFSEGILVECDTVPNLLAHKNGLFSTLVMTNK
What is the function of this protein?
Subunit of ATP-sensitive potassium channels (KATP).  Can form cardiac and smooth muscle-type KATP channels with KCNJ11.  KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
What are the official names of this protein?
ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ERA_STAA1
Sequence: MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SODM_STRGR
Sequence: ATYTLPEPPYDYAAL
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe-Zn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: OR4L1_HUMAN
Sequence: MDLKNGSLVTEFILLGFFGRWELQIFFFVTFSLIYGATVMGNILIMVTVTCRSTLHSPLYFLLGNLSFLDMCLSTATTPKMIIDLLTDHKTISVWGCVTQMFFMHFFGGAEMTLLIIMAFDRYVAICKPLHYRTIMSHKLLKGFAILSWIIGFLHSISQIVLTMNLPFCGHNVINNIFCDLPLVIKLACIETYTLELFVIADSGLLSFTCFILLLVSYIVILVSVPKKSSHGLSKALSTLSAHIIVVTLFFGPCIFIYVWPFSSLASNKTLAVFYTVITPLLNPSIYTLRNKKMQEAIRKLRFQYVSSAQNF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4L1, Olfactory receptor 4L2, Olfactory receptor OR14-28.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F16PA_PARPJ
Sequence: MALQRRTTLTKYLIEQQRETNNLPADLRLLIEVVARACKAISYHVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLEANEWGGNLAGMASEEMEQFFPIPANYPKGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQPTEQSFLQPGTQQVAAGYAVYGPQTVLVLTTGNGVNCFTLDRELGSWVLTQSDMRIPVETREYAINASNERHWYPPVEQYIGELKAGKDGPRQSDFNMRWIASMVADVHRILNRGGIFMYPADKRTPDKPGKLRLMYEANPMAFIVEQAGGAATNGEKRILDIQPKSLHERVAVFLGSKNEVDRVTRYHLETKK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB41_MYCTO
Sequence: MKTTLDLPDELMRAIKVRAAQQGRKMKDVVTELLRSGLSQTHSGAPIPTPRRVQLPLVHCGGAATREQEMTPERVAAALLDQEAQWWSGHDDAAL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.
What are the official names of this protein?
Antitoxin VapB41.
Protein: RL2_ACET2
Sequence: MPVKKYNPTSPGTRFMTVSTFEEITKKEPEKSLLAPLKKTGGRNSYGRITVRHHGGGAKRKYRIIDFKRDKDGIKAKVAAIEYDPNRTAYIALLHYVDGEKRYIIAPHGLKVGDIVESGENADIKPGNALPLENIPVGTEIHNIELKPGKGGQLVRSAGNVAQLMAKEGNYAQIRLPSGEVRMVSLKCKATIGQVGNIDHENVSIGKAGRKRWMGIRPTVRGVVMNPVDHPHGGGEGKSPIGRPSPVTPWGKPTLGYKTRKKNKASDKFIIKRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CLPP_STRS2
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGKTVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VODM_VIOOD
Sequence: GAPICGESCFTGKCYTVQCSCSWPVCTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Vodo peptide M.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: SSB2_STAAC
Sequence: MLNRTVLVGRLTKDPELRSTPNGVNVGTFTLAVNRTFTNAQGEREADFINVVVFKKQAENVKNYLSKGSLAGVDGRLQTRSYDNKEGRRVFVTEVVADSVQFLEPKNNNKQNNQQHNGQTQTGNNPFDNTEEDFSDLPF
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: ORYN_ASPOR
Sequence: MAVAELPNIVSTDSSPSPHPGSRLSSEPTDIESQKAPSNAEPKTDPNLVTWDGPDDPANPQNWSFAYRAFVTAIWVYGNLCTCIASSIFSSGSGQIAQRFHVGSTVVTLGISLFLLGYTVGPPVWGPLSERFGRKWPMVIGMALFTIFCIPVAVAKNLQTVLIGRFLTGVFGAAPLSLVGGSLVDMWNPAQRGVAMACCIGTIFGSPVLAPLMGNFIVESYLGWRFTQWLSCIMGGSCTVLVVFGLPETFAGSILRKKAAAIRKAGNPDVHTVYDGKQKGIKDIFVIFLLRPFALLVTEPILLLVTIYQAFIYGILYLVFVSYPIAFREVRGWSLGISALPYIGMMVGILIGCAIVVIQTRRNYDGNKAVVPEQRLPLMIAGGCLLPVGLFIFAWTSNPNIHWAGMVIGSAPVGTGMYMVFVQCLNYLVDVYPTIANSAIGANTFVRSFFGAGFPLFGPFMYHNLGVAWASSTLGFISIAMIPIPVLFYRYGARIRSWSKNSKHT
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone.
What are the official names of this protein?
MFS-type transporter oryN, Oryzines biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TTCA_VIBVY
Sequence: MTEQILERTKAQQYNFNKLQKRIRRNTGQAIADFNMIEDGDRIMVCLSGGKDSFTMLDILMSLQKSAPISFSLVAVNLDQKQPGFPAHVLPEYLESLGVEYKIVEEDTYSIVQDKIPEGKTTCSLCSRLRRGILYRTAKELGATKIALGHHRDDILETLFLNMFYGGKMKGMPPKLVSDNGEHVVIRPLAYCREKDIIKYSDMAGYPIIPCNLCGSQPNLQRQNIKQMLNDWDKRFPGRIETMFRAMQNVVPSHLADFELFDFKSINKDSGVINGGDIGFDKEEMPVATVEDEDMVQEFDPSLKLDVTNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_PROM1
Sequence: MQCPSCQNTDSRVLESRSADSGRSVRRRRECLNCDFRFTTYERVETTPINVLKRSGAKELFNRSKIINGLNRACEKTLIHGSKIEFIVDEIELELHQGVCKEIKSIEIGEMVLTHLKDINEVAYIRFASVYRQFNGINDFMKTLEALKPIKKEQLASVI
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DEF_YERP3
Sequence: MSVLQVLHYPDERLRKIAAPVKEVNGEIQRIVDDMFETMYAEEGIGLAATQVDVHQQIIVIDISENRDQRLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELETDGLLAICIQHEMDHLIGKLFVDYLSPLKRQRIRQKLEKMAKLNARAN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: GALT_PSEPU
Sequence: MLKPPVDAPIDVKDWIDNRPIAAYQWLILVLCFLIVLFDGFDVAVMGFIAPSLMQDWGLSRAAFGPVMSAGMVGLAIGALTAGPYADRLGRKKVLLIAVSGFSLLSLACAFARNPYELAVLRLLTGIALGAAMPNCTTLLAEYLPTRNRSLMITIMFTGFNMGSGLGGFLSAWLIPHHGWKSVLLAGGLLPLALLPLLWWLLPESARFLAARQAPASQIAAALAKLGGRFAAGTRFTVSEPTTQHKAPARQLFSERYRFGTLALWLTYFMGLLVIYLTMGWLPTLLRDGGLSIERAATITGLFQIGGAVGAIVVGWIMDRRNPNRVIAIAYALGGLCIVSLGALSLESSLLVVGVAAAGFCMSGAQTALNAFAPGYYPTEFRATGVSWMLGIGRFGAIFGSLIGGAVLSLGLGLPLLFTLLGLPAFAAALAILANGHARLRATPAVTAP
What is the function of this protein?
Transporter that specifically mediates the uptake of gallate.
What are the official names of this protein?
Gallate transporter, Gallate permease.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TORC_ECO57
Sequence: MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRAGANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
What is the function of this protein?
Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA.  Acts by transferring electrons from the membranous menaquinones to TorA.  This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal domain of TorC, then from the N-terminus to the C-terminus, and finally to TorA.  TorC apocytochrome negatively autoregulates the torCAD operon probably by inhibiting the TorS kinase activity (By similarity).
What are the official names of this protein?
Cytochrome c-type protein TorC.
What is the protein family that this protein belongs to?
Belongs to the TorC/TorY family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: 3MGH_BORAP
Sequence: MDRYFFLQDASTVAKLLLGNLLIRKIDKKEIVVRIVETEAYMGITDSACHSYSGKRTNRTNAMYNIGGYSYVYIIYGMHHMFNIVTADKNNPQAVLIRSVEPVSPLLGEKCVLTNGPGKLTKFLNIDLAFNKVDLIGNNELFLQRGLNLDFNIVCSKRININYAQEDDINKLWRFYIEGNKFVSRC
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: NCAP_TSWVH
Sequence: MSKVKLTKESIVALLTQGKDLEFEEDQNLVAFNFKTFCLENLDQIKKMSIISCLTFLKNRQSIMKVIKQSDFTFGKITIKKTSDRIGATDMTFRRLDSLIRVRLVEETGNSENLNTIKSKIASHPLIQAYGLPLDDAKSVRLAIMLGGSLPLIASVDSFEMISVVLAIYQDAKYKDLGIDPKKYDTREALGKVCTVLKSKAFEMNEDQVKKGKEYAAILSSSNPNAKGSIAMEHYSETLNKFYEMFGVKKQAKLTELA
What is the function of this protein?
Encapsidates the RNA.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the tospovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: GLIP1_HUMAN
Sequence: MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGNYPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIVNSVILILSVIITILVQHKYPNLVLLD
What are the official names of this protein?
Glioma pathogenesis-related protein 1, GliPR 1, Protein RTVP-1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CEP41_XENTR
Sequence: MSAKRSIGDSEILKKRIPQNLKYQHIKTRLDTGNSMTKYLEKIEEIKKNYRYKKDELFKRIKVTTFAQLVLQVASVSEERESGEMTTDELQRLEDNSSVISDTEFLTDRTNGKGSPVNDSKSPIQFIDSERGEECIHTSRSTLQSVISGVGELDLGNQADKKKESLQSSSALDKPYEDCPFLLLDVRDRDSYDQCHVVGAKNYPVAMLSRTMNPFTPEILEYRNAHGKIIILYDEDERIASQAATTMCERGFENLFMLSGGLKVISQKFPQGLTTGSFPVTCLVPPTQMKSALKRTPKDPIVPAEDKWRFSSQDLEMIENHLENMLMSTSTPSRLRMDSRNSKVPSSASSARSQSSTSSHSKPWK
What is the function of this protein?
Required during ciliogenesis for tubulin glutamylation in cilium.  Probably acts by participating in the transport of tubulin polyglutamylases between the basal body and the cilium (By similarity).
What are the official names of this protein?
Centrosomal protein of 41 kDa, Cep41, Testis-specific gene A14 protein.
What is the protein family that this protein belongs to?
Belongs to the CEP41 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes mainly to the cilium basal body and in primary cilia.
Protein: YLH3_CAEEL
Sequence: MDEVANALAVSQTMMEKMQKLEISKNYDVEKFETLLRLPARDVNTFMEKEAKKTDDEKMTDMDRRIKRIREDKTDRAARTLQKYFRKIRVKGEQNHINKRISKIPAKRRVVLLEQIRQKMGEQQPIRRFGGYQVIRAVELHKGKQKLQKDWLAKLSIDVNFHDKNLSRPNSPTHFIANSIPTLIRKKAEMKHAEKMQEIDSSIMDIYCGFQKDNLH
What are the official names of this protein?
Uncharacterized protein C48B4.3.
Protein: METAA_BACC1
Sequence: MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPLKEKMFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRESDIREVKELTLLANSEEAGVHLVIGQEGRQVFALGHSEYSCDTLKQEYERDRDKGLNIDVPKNYFKHDNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.  Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl-enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine.  Cannot use succinyl-CoA as the acyl donor.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BACAA
Sequence: MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEALGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVSKIPVKDYLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELLDAAEQGIFQLIDIQKEALGDIVSHIE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: Y1582_METJA
Sequence: MRDVKYVDAHCHIEDKAFNKNRDEVIERAKKEDVIIVTSGASLGGCLRALELRKKYNIYLTLGYHPSRVKADDKVIEKVYNLIKNNEYEILAIGEIGMDIKDENYKRQEEIFKKFLSLAEELNKPIVVHARGFERKIFDIAKDKVDIMFHCYSGDVELAKEIGKEGHLISISTLVCFSEHHKKLVESLDLEYLTTETDSPYLSPIKGTKNEPKNVKLVIEEIAKIKEMEVEEVKDVIYKNTCKFFKRRL
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase MJ1582.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: RNPA_BACMK
Sequence: MKKKNRIKKNDEFQAVFQKGQSNANRQFVVYKLDKEKQPHFRIGLSVSKKIGNAVVRNRIKRMIRQSIIELKDEIDSGKDFVIIARKPCAEMTYEELKKSLIHVFKRSGMKRIKK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MTMR1_MOUSE
Sequence: MDRPVAAAAAASAASCEGAGGPGPGPGASWRPSRVAGGASASSRHPSIETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFMGAVSGTLTVTDFKMYFKNVERDPHFVLDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQVLFAFNYKEKFPVNGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEKEWISFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNYENHVLYPVASMSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAIKAELQKRVEDLQREMATRTISSSSERGSSPTHSATPVHTSV
What is the function of this protein?
Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no activity with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:12217958).  Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been shown for the human ortholog (By similarity).  In contrast, PubMed:12217958 find no activity with this substrate.
What are the official names of this protein?
Myotubularin-related protein 1, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: DXS_HAEIN
Sequence: MTNNMNNYPLLSLINSPEDLRLLNKDQLPQLCQELRAYLLESVSQTSGHLASGLGTVELTVALHYVYKTPFDQLIWDVGHQAYPHKILTGRREQMSTIRQKDGIHPFPWREESEFDVLSVGHSSTSISAGLGIAVAAERENAGRKTVCVIGDGAITAGMAFEALNHAGALHTDMLVILNDNEMSISENVGALNNHLARIFSGSLYSTLRDGSKKILDKVPPIKNFMKKTEEHMKGVMFSPESTLFEELGFNYIGPVDGHNIDELVATLTNMRNLKGPQFLHIKTKKGKGYAPAEKDPIGFHGVPKFDPISGELPKNNSKPTYSKIFGDWLCEMAEKDAKIIGITPAMREGSGMVEFSQRFPKQYFDVAIAEQHAVTFATGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRAGIVGADGATHQGAFDISFMRCIPNMIIMTPSDENECRQMLYTGYQCGKPAAVRYPRGNAVGVKLTPLEMLPIGKSRLIRKGQKIAILNFGTLLPSALELSEKLNATVVDMRFVKPIDIEMINVLAQTHDYLVTLEENAIQGGAGSAVAEVLNSSGKSTALLQLGLPDYFIPQATQQEALADLGLDTKGIEEKILNFIAKQGNL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: T10B_RAT
Sequence: MEHQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEACLHSCAGKLIHSNHRLMAAYVHLMPALVQRRMADYEAASAVPGVPAEQPRDSPSGS
What is the function of this protein?
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force.  In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10 B, Fracture callus protein 1, FxC1, Mitochondrial import inner membrane translocase subunit Tim9 B, TIMM10B, Tim10b.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: CYB_SORPC
Sequence: QILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPVNPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAFIPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: B2MG_HORSE
Sequence: MARVVALVLLGLLSLTGLEAVPRVPKVQVYSRHPAENGKPNFLNCYVSGFHPPEIEIDLLKNGEKMKVDRSDLSFSKDWSFYLLVHTDFTPNGVDEYSCRVQHSTLKDPLIVKWDRDL
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.