PharMolix/UniProtQA huggingface dataset:
Protein: EPMA_BUCAT
Sequence: MKKKIWKSSASIEDLIKRSNIISNIRLFFSKKNILEVETPILSRSTVTDVHLTSFETNYISSDNIDELKLWLTTSPEYHMKRLLASESGSIYQICHSFRNKELGRYHNPEFTMLEWYQPFCSMKKFIKEIDIFLQIILKCNKSDKVSYQDLFIDFLKIDPLCANLLELHQISKKLKLDHLTHSENNLNKLIQLLFTLKIEPNIGKEKPLFVYHFPAEQASLAAINLKDPRISERFEIFFKGIELGNGFYELIDVNEQKKRFIRDNKERRSMNLPIRKIDNFFLSALSYGLPPCSGVAIGLDRLIMLILNKKSIHEVIAFPVDRC
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RIMP_ACTSZ
Sequence: MATLEQNLQEMLQGSVEDLGCELWGIECQRAGRFMTVRLFIDKEGGVSVDDCADVSRQVSAILDVEDPITDKYNLEVSSPGLDRPLFTLSQYERFIGEDITIHLRIPVSDRRKWQGKLEKIENDTVTLTVDGQPQVFVFGNIQKANIIPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATS4_MOUSE
Sequence: MSQMGLHPRRGLTGHWLQRFQPCLPLHTVQWRRLLLLAFLLSLAWPASPLPREEEIVFPEKLNGSSILPGSGVPARLLYRLPAFGEMLLLELEQDPGVQVEGLTVQYLGQAPEMLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAELHLQPLEGGALNSAGGPGAHILRRKSPASSQGPMCTVKAPSGSPSPISRRTKRFASLSRFVETLVVADDKMAAFHGTGLKRYLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQEGPQVGPSAAQTLRSFCTWQRGLNTPNDSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCTNLNGQGGSSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAPLHLPATFPGKDYDADRQCQLTFGPDSSHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGSSQACMGGRCLHVDQLKDFNVPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTENCPHGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQARALGYYYVLEPRVADGTPCSPDTSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSRCSKQSGSFKKFRYGYSDVVTIPAGATHILVRQQGGSGLKSIYLALKLSDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQPLTLQVLVAGNPQNARLRYSFFVPRPVPSTPRPPPQDWLQRRAEILKILRKRPWAGRK
What is the function of this protein?
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover.  May play an important role in the destruction of aggrecan in arthritic diseases.  Cleaves aggrecan at the '392-Glu-|-Ala-393' site (By similarity).
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-4, Aggrecanase-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL4_MARN8
Sequence: MELTITGSGKGISVSDAAFAKDFNEALVHQVVTAYMAAGRQGTKAQKTRSEVSGGGKKPWRQKGTGRARAGTIRSPIWRSGGVTFAAKPRDFEQKVNRKMYRAAMRSIFSELVRQERLVVVDDMNVDTPKTKAFTAKLSDLGVSNALILSENVEQNLHLASRNVPHVDVRDVAGLDPVSLVAFEKVVVTVPALKKIEEMLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TNSD_ECOLX
Sequence: MRNFPVPYSNELIYSTIARAGVYQGIVSPKQLLDEVYGNRKVVATLGLPSHLGVIARHLHQTGRYAVQQLIYEHTLFPLYAPFVGKERRDEAIRLMEYQAQGAVHLMLGVAASRVKSDNRFRYCPDCVALQLNRYGEAFWQRDWYLPALPYCPKHGALVFFDRAVDDHRHQFWALGHTELLSDYPKDSLSQLTALAAYIAPLLDAPRAQELSPSLEQWTLFYQRLAQDLGLTKSKHIRHDLVAERVRQTFSDEALEKLDLKLAENKDTCWLKSIFRKHRKAFSYLQHSIVWQALLPKLTVIEALQQASALTEHSITTRPVSQSVQPNSEDLSVKHKDWQQLVHKYQGIKAARQSLEGGVLYAWLYRHDRDWLVHWNQQHQQERLAPAPRVDWNQRDRIAVRQLLRIIKRLDSSLDHPRATSSWLLKQTPNGTSLAKNLQKLPLVALCLKRYSESVEDYQIRRISQAFIKLKQEDVELRRWRLLRSATLSKERITEEAQRFLEMVYGEE
What is the function of this protein?
TnsABC + TnsD promote high-frequency insertion of Tn7 into a specific target site known as att-Tn7 whereas TnsABC + TnsE promote low-frequency insertion into many different sites.
What are the official names of this protein?
Transposon Tn7 transposition protein TnsD.
Protein: KU_PSESM
Sequence: MARAIWKGAISFGLVHIPVALVSATTSNSVDFDWLDKRSMDPVGYKRINKVTGKEVTKENIVKGVLHEKDRYVVLSEEEIRSAHPKSTQTIDIFAFVDSQQIPLQNIDTPYFLTPDKRGEKVYALLRETLVDTQKVALANVVLHTREHLAAVMPLESALVMVILRWPADVRELDALELTEAVTDARLTKSERDMARRLVKDMSADWQPDQYHDTFQEKIMQLVQTKAGEGKIEDVETDPGEEERKSADVIDLTDLLRRSLAGKSSASKTRKPAAKDKVADKQSPKPKRPAVRKKTGKAS
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: AR6P6_HUMAN
Sequence: MSFAESGWRSALRRRGPGTPGPVARPSYSSFTQGDSWGEGEVDEEEGCDQVARDLRAEFSAGAWSEPRKRSVLPPDGNGSPVLPDKRNGIFPAAAGSRAQPRRWPVQVLSILCSLLFAILLAFLLAIAYLIVKELHAENLKNEDDVDTGLLGFWTLLIISLTAGFSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCLM
What are the official names of this protein?
ADP-ribosylation factor-like protein 6-interacting protein 6, ARL-6-interacting protein 6, Aip-6, Phosphonoformate immuno-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the ARL6IP6 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: NU3M_BRANA
Sequence: MMLEFAPIFIYLVISLLVSLILLGVPFLFASNSSTYPEKLSAYECGFDPFGDARSRFDIRFYLVSILFLIFDLEVTFFFPWAVSLNKIDLFGFWSMMAFLFILTIGFLYEWKRGALDWE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MNCP_OXYFA
Sequence: MPTQMEVEYWRRRYQRMNYERFAAANVIALITHAATQPLDMVRIRSQMLQEGKTFSGLGYQKGWYPFQIMEEIYAAGGGLRKFYSAFDTFFFRTVCYTTARVTAFGYFYDKVNKDPRRVARPDFLVAAGVLGGFIAGVVTNPIDIVYNRMQVDELYPQAARRNYSNTIQGLAKVAEEGALFRGAGANGFKLAAICSSMTNIYDWCKENSYFFFGPHWINRLWGTAVAVAIGTVVSMPFDMIRTRLHTMRPLPNGQMPYNGMIDCFNKIIKYECNSKWMSNFGSFYAGGEAYFLRLFLICYLSQFLVDYYNENYYDQEFWQPQRFHYQSGIDYDIHDPYTDAFNKKLVATYTTATGGMGAAHPSGKENLAII
What are the official names of this protein?
Macronuclear solute carrier homolog CR-MSC.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RLMH_STRZT
Sequence: MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTPDKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFSTLTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2255_BACP2
Sequence: MEGWRISHLNEHKHERTIYVDADACPVKDEILSVASQFQIPVTFIASYEHFQTKRSPLEDWRFVDTHKEAADLVIANSVAAHDIVVTQDIGLASLLLPRQVIVLSERGRMYTNETIDFDLERRHVSSKQRRKGVYGKGPKKLLEEDKKRFIAQLQKILSNHEGFLN
What are the official names of this protein?
UPF0178 protein BPUM_2255.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RS10_SHIDS
Sequence: MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL7_BACC0
Sequence: MTKEQIIEAVKSMTVLELNDLVKAIEEEFGVTAAAPVAVAGGAGEAAAEKTEFDVELTSAGAQKIKVIKVVREITGLGLKEAKELVDNTPKVIKEAAAKEEAEEIKAKLEEVGAAVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: LYSC_CHLAE
Sequence: MKAVIILGLVLLSVTVQGKIFERCELARTLKRLGLDGYRGISLANWVCLAKWESGYNTQATNYNPGDQSTDYGIFQINSHYWCNNGKTPGAVNACHISCNALLQDNIADAVTCAKRVVRDPQGIRAWVAWRNHCQNRDVSQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: RS3_CITK8
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL13_SACS2
Sequence: MSTQVQEQVVIINAEGQILGRMASNVVRLLKEGKKVIIVNGEKAVISGEKNRVIESYKLLLTVKTLFNPYRNGIRRPRSPINIVKRTIRGMLPKSSKGRRMLKNVKIYVGVPKEFEGRQFIKFPDSDVSRLKGKYVTVEVVSKELGWSG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DNAA_COXB2
Sequence: MSLPTSLWDKCLGYLRDEIPPQQYNTWIRPLHAIESKQNGLLLLAPNRFVLDWINERFLNRITELLDELSDTPPQIRLQIGSRSTEMPTKNSHEPSHRKAAAPPAGTTISHTQANINSNFTFDSFVEGKSNQLARAAATQVAENPGQAYNPLFIYGGVGLGKTHLMHAVGNAILRKDSSKKVLYLHSERFVADMIKALQHNAMNEFKRFYRSLNALLIDDIQFFAGKDRSQEEFFHTFNALLDGQQQIILTCDRYPKEINGLEERLQSRFGWGLTVAIEPPELETRVAILMSKAEQLKVHLPHEVAFFIAKHIQSNVRELEGALKRVIANAHFTGQSITVDFTREALKDLLTLQARLITIENIQKTVAEYYKIKVADLLAKRRNRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKVKELLATSLDILEDYKNLMRILSG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX15_PARSR
Sequence: DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF
What is the function of this protein?
Potent voltage-gated sodium channel blocker (PubMed:24211312).  Potently inhibits the voltage-gated sodium channels Nav1. 7/SCN9A (IC(50)=0. 58-10 nM) (PubMed:24211312) (By similarity).  Shows a moderate activity on Nav1. 1/SCN1A (IC(50)=6 nM), Nav1. 2/SCN2A (IC(50)=5-128 nM), Nav1. 3/SCN3A (IC(50)=20. 3-170 nM), and Nav1. 6/SCN8A (IC(50)=17-20. 1 nM) (PubMed:24211312) (By similarity).  Shows an unclear inhibition of Nav1. 4/SCN4A (IC(50)=200 nM to >10 uM), Nav1. 5/SCN5A (IC(50)=140 nM to >10 uM) and Nav1. 8/SCN10A (IC(50)=68-12200 nM) (PubMed:24211312) (By similarity).  Weakly blocks the low voltage-gated calcium channels Cav3. 1/CACNA1G (30% inhibition of the peak current by 9. 8 nM of the toxin) (By similarity).  It shows moderate affinity for lipid bilayers (By similarity).
What are the official names of this protein?
Toxin GTx1-15, Beta/omega-theraphotoxin-Gr2a, Beta/omega-TRTX-Gr2a, Toxin GpTx-1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 08 (Gtx1-15) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AMYP_RAT
Sequence: MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL
What are the official names of this protein?
Pancreatic alpha-amylase, PA, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ANXA3_HUMAN
Sequence: MASIWVGHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLKICGGDD
What is the function of this protein?
Inhibitor of phospholipase A2, also possesses anti-coagulant properties.  Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate.
What are the official names of this protein?
Annexin A3, 35-alpha calcimedin, Annexin III, Annexin-3, Inositol 1,2-cyclic phosphate 2-phosphohydrolase, Lipocortin III, Placental anticoagulant protein III, PAP-III.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: MOK12_SCHPO
Sequence: MLFFSIPTILLIFFLFIQIITAAFLTDENEPWNLNRNWTAQKILDYSAEWNSHEYFPSPSNWRALPFYTIILDKWTNGVPENDVAEDTVFESDPYEVTFRAGGDIVGLVTPRSLDYLESMGIKAVYIAGTPFQNLPWYPDGYSPLDFTLLDKHTGTLNQWHEAIMKLHERGFYVVVDFTISTLSELSYFVNSSMSFANTSAPFSTKGYKMKYKHPEYHYTDFQLSNGSSYSCNAPTFWDVTGLPINNTEDLNSISEVMCLSGDFDHYGDVEAFGNHPPWWRQLSNFASVQDRLRDWDPIVAKKLKHLGCLAVKMLDIDGIRVDKATQITADFLGDWSAYIRQCAREIGKENFFIPGEVTSGADFGSIYVGRGRQADQRPNNREIALQTGYNESKYFLRKESDSALDSVSFHYSVYRTLTLLLGLQGELFAAFDLNRHDFAAMWNQMLIQDDMINANTKKFDPRHLYGLTNQDIFRWPSIKDGRFKQLLGLFVVHLLMPGIPLIYYGEEQNLKLLDNQAANYIFGRQPITSSIGWQKHGCYQIGTTQYTDLDFGPASEACRDDWNSLDHLDPTSPTKHYIARMNEIRSYFPQVRDGWDLKLIGKWTHEGTFPGNELYGESNPTTWGLWSMIRGPLAPYQKFSDQNDYIWLIFTNENTTKTYDMDCMRQVDNKFPPYPALLGPYSSGSTVKNLLYPYEEIDLSTSTIDSPDIGNIGCIPHLTIDAYGSKIFVKKEDWIRPSLYLTKFLPGHDSRIYSATEVTSFKISLGFSEEVDCKDLFKRIGFNSRTLNSSFAPKILEDSISCGYLDQPAPQEYTNAPVTKWFFNATLDSVPNGMHELLLNEVKSTSNQTMQSKIARLIFRVGNEENPLVYPNNATFSPSLLYKASNGDLYVNHTGAGADKYRFSLNYGGTYSKWKTVSTPSEKLRKPTWNGTNLQKWDGDHLIVQYWSSIALSTAHVQHGDTLNYSRQFPNLFVQGAFNRFGYDGSMPSKMSYNLENRTWSYDLISTWPAELVLNVWGMNPDNNADQGWVYGDLDNDTIIDRVPPGSSRISNFIRFLDPPPKPYLSYKMYLNDFTRQLHYIPKGSWTVQIVAIVLLILLPPLFGIFSVALYSGAFSRVTIFNGSHNRGIKVAKQKIKSIMSRIFPFSVHLPLDNSSELLKQLPESEKRLNVLVATLEYDVPDLGIRVKIGGLGVMAQLMGQHMEFQDMVWVVPIISGVEYPFDKLCTEPKIAVKIGDDEFVVNCYSYKSGNITYVFLQSEVFYKQSSKEPYPLKMDDLASAIFYSVWNQCIAEVWKRFPLDIYHVNDYHGALAPLYLLPEVIPVAVSLHNAEFQGLWPLRTSAELECVCSIFNIEKDICTKYVQFGHVFNLLHSIISYVRKHQGGYGVVAVSDKYSKQTLSRYPIFWSLVHISGLPNPDPSDLKLLNHLTDDPVDVDFVLEAKRKLLKKQTQEWANLDVDPSAQLLVFVGRWSHQKGIDLIADLAPKLLTEHNVQLITIGPVIDLHGQFAAEKLEQIAKRFPTRVLCKPVFTAVPPFLFAGTDFALIPSRDEPFGLVAVEFGRKGVLCIGSRTGGLGHMPGWWFQMASPNTGHLLTQFENAITKALHSNGELRARLRVEALRQRFPVCIWKQKSENLLKSCIYVHEMETLKHASPTFKAYQFVVRICHYLTSKVKSINKDQVFNAFSPDVSERPPLFEVASCSNETDSVEKLTPELSVSPESDMHFKDGNSSKLEIVESKEIYASDSDISNSTSEDINKDECVSKDIEVDNFALNLQSQSYEGDSNDFGIREVPLSDANQSSQADSTSIDRYGPYSSQKVNFSKYKDFVESRPTFFQSSVTFTDADGSTRKTFSKRLENLTTSNTLKSLSVDHFIRKHERKYFNGLRKQEIDVKLKSRSDKEKSCTVSESYKQIDCDTYEATRLQKLLLHSIGGWPLYTIVLAIGQILGASSYQLTLLSGESAQSTVSMYILLSIFSFFSLFWWFLSRVVQARYILSLPFFFFGISFILVAITHFFQKTTACSVIQHIAAYVYAISSSTGSLYFAWNFGAEGGIATHHWILRACLVHGIQQIWSAILWSWGDLLSKKDLTQNVGPGIFAGGLIASFICFGLSYVTFAGLPAFYRQAPSIIPAFYRSLGKRNIVIWFFISQILINYWLAVPYGQAWRFFWNTSNTPLWSIIILLLIFFIVVWAVLLSVIKILSLNNVWFPVIFGLGLICPRWCLEFWSSSGLGINLPWAGKASALLTKSVWLLLALWDGIQGVGVGVMLLQTLARDHVAFTLMLAQVISCITIMIAKPSLPVSDRVFPNLGAWNPSEGPGPCASPCFYIALICQFVAVGGLLYHYRKSQLAL
What are the official names of this protein?
Cell wall alpha-1,3-glucan synthase mok12.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
Protein: ATPG_BACC2
Sequence: MASLRDIKAKITSTKKTSQITKAMEMVSASKLNRAEQNAKSFVPYMEKIQEVVASIAQGSKGINHPMLNARPVKRTGYIVITSDRGLAGGYNSNVLRTVSNVIRERHNMDSNQYSIIVLGRLGRDYLKRRGFNIIDEVVGLSDHPSFTDIKDLASRAIAMFADGAYDELYIYYNHYVSKISQEVTENKILPLTDVASDKPTTAYEFEPSEEEILKVLLPQYAESLVYGALLDGKASEHAARMTAMKSATDNAMEVIDSLTLSFNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNK_DROME
Sequence: MKICGPKLSLCGLIISVWGIVQLVLMGLFFYINSVALIEDLPLEEEYHSLEDFYAAANRAYNQNAYNCWIAACIYVLTLLLSAQQFYMNSRVTAN
What is the function of this protein?
(Microbial infection) Required for the initial stages of clathrin-mediated endocytic uptake of a diverse set of flaviviruses, including dengue and West Nile (PubMed:26056282).  Not required for clathrin-mediated endocytosis and macropinocytosis (PubMed:26056282).
What are the official names of this protein?
Ribonuclease kappa, RNase K, RNase kappa.
What is the protein family that this protein belongs to?
Belongs to the RNase K family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLGC_MYCLE
Sequence: MREVPQVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLVDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRFGPHWYTGSADAIYQSLNLIYDEDPDYLVVFGADHVYRMDPEQMLRFHIGSGAGATVAGIRVPRSDATAFGCIDADDSGRIRRFTEKPLKPPGTPDDPDKTFVSMGNYIFTTKVLVDAIRADADDDHSYHDMGGDILPRLVDGGMAAVYDFSQNEVPGATDWDRAYWRDVGTLDAFYDAHMDLVSLRPVFNLYNKRWPIRGESENLAPAKFVNGGSVQESVVGAGSIISAASVRNSVLSSNVVVDNGAIVEGSVIMPGARVGRGAVIRHAILDKNVVVGPGEMVGVDPERDREHFAISAGGVVVVGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: APT_RHORT
Sequence: MNLKDHIREVPDFPKPGILFYDISTLLADPDAWQVTMGRMAKVVAPRLPDVLAGIESRGFLVAAPLALKLGLGFVMVRKKGKLPGATVRHEYALEYGTDTVEVQEGAVLPGQRVVILDDLLATGGTLNAASELLGKMGANVVGAACIIELSFLKGRERTKVPIDSLVAYDS
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_BARBK
Sequence: MIIRHLSENIINQIAAGEVIERPANVIKELVENAIDAQATRIEISIVNGGKNFIRVSDNGCGIPADQLTLAVSRHCTSKIVDDVSNICFLGFRGEALPSIGSVAKLKLTSRTQDADNANEISVIAGKIEGPKPAAANPGTIVEVRDLFFVTPARLKFMKTDRAETSAITDMIKRIAIAFPHIRFSLSSTDRMLMEFPATENNTQGQLQRITQIMGKEFAPNSIALNAERESVRLTGFTCLPSFNRSNSLHQFAYVNGRPVRDKLLWGAIRGAYADAIARDRHAVSIIFIDLPPADVDVNVHPTKADVRFRDPGLIRGLIIGAIHEALHQAGVRHTSTHSESVLTAFQIHPLENLKSAQRPFSYTSQPYHRVSTTTSMLQKPLDDSIDLREGIVPMMECLSAPSSDTRATIQTSPTEELHYPLGAAKAQIHKNYIISQTQDSLIIVDQHAAHERLVYEALKNALYSKPLSSQLLLIPEIVELSEEDAACLLTHKDSLQKFGLGIEPFGPGAILVRETPAMLGEINAQALIKDLADEAAEYDTTNNLKAMLDYVAATMACHSSVRSGRLLRPEEMNALLRQIEETPHSSTCNHGRPTYIELKLADIERLFGRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MDS3_YEAST
Sequence: MPLLQPSTCFCYPLKLPPLPLTSDSNEFDECARKRLTLDYRTGSAVTLTRSNIFVHGGLTIPLNLPVVNSMQLQKELILFFAKEKNNGSSFRNLNEWISKETFFLDLMSRTWYRVKTSFDQRTEELLKAESSSAKADNDTNEIRTDIKKGKSLESPLKERLFHSLCYLDGCLYIFGGLTVSPQSGYELIATNELWKLDLNTKKWSLLSDDPQIARRFNHTMHVKNENNDNRDTKLIIVGGLNNMDQPVKKIDIYNISQNCWQSETIPKQPMEITTNVNGIPLALSKDQNFSILVENNEANVPALAFYMRSDQIDEYLGKDSSKIKENSPIVALPLLSESQGIRMPSNPALPKKLLNVPYELLAPTGDYFGFNIIIGGFHPNYQSSNFHCFIYDINSGKWSRVATACPDCDINKHRFWRVFVWKSHHQTILLGTKTDDYYSPSVQRFDHLSTFGLPLVNIFNKTIQLPHHKISASSLPIPIENFAKHKDTPLKKVSFTSSATSQFENYIRYIAPPLEMSSIQSVFPPYAMVLGKDALEIYGKPLSDFEFITSEGDSIGIPCYLLRKRWGRYFDMLLSQSYTKVCADYETTDTQSTLIKFSPHSSRNSSKAVRQEGRLSSSGSLDNYFEKNFPIFARTSVSEAQNTQPQVANADAKAPNTPSTSDEPSSSSSSDLYSTPHYQRNNDEEDDEDPVSPKPVSKSNSIYRPIRKTESSSTTSSSNGMIFRVPFKEKAAVTSNTEALLESNLSLQELSRRRSSLMSIPSGELLRSSISEAEHQRRASHPLTSSPLFEDSGTPCGKQLQQLQQHTIQNPHNHLSPRRFSRSARSSISYVSSSSDRRGNSISSRSTSDSFGTPPVLGVLNVPLPPQTREPNEPPPPCPAMSTGSNTRRSNTLTDYMHSNKASPFSSRRSSHIGRRSSTPETENAFSATPRASLDGQMLGKSLKEGSTSQYTQPRMNSFPKANETIQTPTSSNNEWSRQSVTSNTDSFDSLQSNFALELEPLLTPRSLYMPWPTSTVRAFAEFFYTGQVNSKWLLAPVALDLLVMAKIYEIPLLYKLILEVLYSILAKKEESLSLICTSLMETFRTKTLNSYKGDEEKTNTYLTSNDNYQELLKLKVSLENIDNGYYDPDLLRKQSRAQSSSTQESSGSANGEKTATGAGSLETSSTNVPTVFAGGPRDSHNSVGSIGFPNSMNIQGSRRSTSGFSPRVKMKSSLSKEIDPKTFYEEYEPKEGKSFDDNDDQQTNIGSFNLHLFDMNYGSISSSSTNSISSSDLEEKEEQEQLQDLLEIEREDSAEILDARFRNKEDDKVTKDISNDKKRNYLPHEKNNLKAKEGKETRDVREEEEEFDFGLGMLSLNKIKREAKHVDKVDDSVDPLFKSSAFPQSPIRAYGSTTRTSSASGKPFRDNRSFNAFSVLTLENMASANALPPVDYVIKSIYRTTVLVNDIRLMVRCMDCIELSKNLRALKKKTMEDISKLKGISKPSP
What is the function of this protein?
Negatively regulates early sporulation-specific genes.  Seems to exert its function by positively regulating the Ras/cAMP pathway.  Required for growth under alkaline conditions.  Acts synergetically with PMD1.
What are the official names of this protein?
Negative regulator of sporulation MDS3, MCK1 dosage suppressor 3.
What are the subcellular locations of this protein?
Cytoplasm.