PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_STAA8
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_BACP2
Sequence: MAIKKYKPTSNGRRGMTTSDFAEITTDKPEKSLLAPLHRKGGRNNQGRLTVRHQGGGHKRQYRIIDFKRDKDGIPGRVATIEYDPNRSANIALVNYADGEKRYILAPKGIQVGTEVTSGPEADIKPGNALPLINIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGKEGKYVLVRLNSGEVRMILSACRATIGQVGNEQHELINIGKAGRSRWKGVRPTVRGSVMNPNDHPHGGGEGRAPIGRKSPMSPWGKPTLGFKTRKKTNKSDKFIVRRRKNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1109_ARCFU
Sequence: MPLPSEVEKAARSGSEYELYKALLLSFGKRGDKAFEYLKRSKVKRYKDFFVVVGKEEYVVEGGFCTCPDFLVNLKGKSPCAHIIAVEVAKITGKYDYIDAYYVDYPDILRKKK
What are the official names of this protein?
Uncharacterized protein AF_1109.
Protein: TRMFO_PARDP
Sequence: MEPIHIIGAGLAGSEAAWQIARAGVPVVLHEMRPQVATFAHRTGDCAEMVCSNSFRSDDDRMNAVGQLHWEMRAAGGLIMAMADRHRLPAGGALAVDRDAFSQAVTQALQAEPLVSFQPGEISDLPSEGHWIVATGPLTSEALGRSIRSLTGEGSLAFFDAIAPIVHAESIDMSICWRQSRYDKGETEEERTAYINCPMTREDYEGFIDALLAADKTEFHEGETAGYFDGCLPIEVMAERGRETLRHGPMKPVGLTNAHNPAEKPYAVVQLRRDNALGTLYNIVGFQTKMKYGAQVDVFRRIPGLQDASFARLGGIHRNTFLNSPRLIDDRLRLRARPHLRFAGQVTGVEGYVESAAMGLLAGRMAAAEALGRDLPPPPATTSMGALVSHITGGADAKTFQPMNVNFGLYPPLDAMRGGRKGRKDRYPAYTDRAKADFQQWVAGES
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRR15_MOUSE
Sequence: MADSGGSSPWWKSLTRKKSKEVTVGVQPQVRPETGQEPSPPHSDRTSSLPENQHSNILGDPGESLRSDKLCEEKTGNSRRNLKISRSGRFKEKRKMRATLLPEGDKSPEEADFPDDPQEDKQ
What is the function of this protein?
May have a role in proliferation and/or differentiation.
What are the official names of this protein?
Proline-rich protein 15.
What is the protein family that this protein belongs to?
Belongs to the PRR15 family.
Protein: UFSP2_RAT
Sequence: MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLNDLTTKLSSDALVFRICNSSVYLWPNSDANTGELTDSSACKSVVDLIQFDQEEDTKRKFMKKKDKKLTDMQQIVNIDLMLEISTPLGAVTPIIERENEEHHYINMSLPIDAVVSVAPEETWGKVRKLLVDAILNQLVDVEKCILRYMKGTSIVVPEPLHFLLPGGKNLVTVLYPSGIPDDQLQAYRKELHDLFKLPHDRPYLKRINAYHFPDELYKDGYIRNPHAYLSPPNIEGSMICMVQGTYAYHHYMQNRVDDNGWGCAYRSLQTVCSWFRHQGYTERAIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMIGGGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNAL
What is the function of this protein?
Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins.  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.  Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation.
What are the official names of this protein?
Ufm1-specific protease 2, UfSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus.
Protein: PYRH_METM5
Sequence: MDVVFALGGSVLMPKEGASTENIQNYAKAFKKLKEMGHRVSVVVGGGNTARQYISVAREFTNESFCDEIGILATRMNSMLLISALGKDAVKQVPENFKDAELILNMDKILVMGGTHPAHTTDAVSATLAEFIDADLLVIATNVDGVYTKDPRCNEDAVKLDKINTKELLEITGSSSMSAGSSGVVDPLASKIIDRAELKTIVVKGIPEEILASVSGDHNGTTITP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPC5_MOUSE
Sequence: MSKNTVSSARFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAVLLQWHEKALAAGGVGSIVRVLTARKTV
What is the function of this protein?
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: IST1_RAT
Sequence: MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPVGVETDLIDVGFTDDVKKGGPGRGGGGGFTAPVGAPDGTMPMPMPMPMPMPSPSPNAPFAYPLPKGPSDFSGLPVGTYQAFPNIHPPQIPATPPSYESVDDINADKNVSSAQIVGPKPEAPAKPPSRPVDNYNTFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT
What is the function of this protein?
ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation (By similarity).  Is required for efficient abscission during cytokinesis (By similarity).  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (By similarity).  During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (By similarity).  Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2 (By similarity).  Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (By similarity).
What are the official names of this protein?
IST1 homolog, Charged multivesicular body protein 8, CHMP8.
What is the protein family that this protein belongs to?
Belongs to the IST1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Nucleus envelope. Note=Localizes to centrosome and midbody of dividing cells. Colocalized with SPART to the ends of Flemming bodies during cytokinesis. Localizes to the reforming nuclear envelope on chromatin disks during late anaphase.
Protein: RL17_STAAT
Sequence: MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TOP2B_CHICK
Sequence: MAKSGGGGGGGGGGGGGGGGSGGLTCVTLFDNQINASKKEESESVNKNDTSKKMSVERVYQKKTQLEHILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKISIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEPKIKHFEGDDYTCITFQPDLSKFKMENLDKDIVSLMTRRAYDLAGSCKGVKVMLNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHEVVNERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFVNCLIENPSFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIIESILNWVKFKAQTQLNKKCSSVKHSKIKGIPKLDDANDAGGKHSLDCTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYEDPESLKSLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHMENHKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNVNLLQPIGQFGTRLHGGKDAASPRYIFTMLSPLARLLFPSVDDNLLKFLYDDNQRVEPEWYIPIIPMVLVNGAEGIGTGWACKLPNYDTREIVNNVRRMLDGLDPHPMLPNYKNFRGTIQELGQNQYVVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTEKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTSLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLHYYSLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKRDLIQMLVQRGYESDPVKAWKEAQEKAAEEEDPQNANDDASSASGSTSGPDFNYILNMSLWSLTKEKVEELIKHRDSKERELNDLKRKSASDLWKEDLAAFVEELEKVEAQEREDVLAGMVGKPIKGKVGKPKMKKLQLEETMPSPFGRRIVPQITSAMKADASRKLLKKKKGDADSVAIKMEFDEEFGGVQAEGGGDDTVNTAASGTKTPKLKREKKEPGTRVRRAPSSTKSSAKKVKKRNPWSDDESKSESDLEESEPVIIPRDSLLRRAAADRAKYTFDFSKEEDDAHDDDDANNNNDLDELKVKASPVINDREDEFVPSDSVEKDEYDFSPVKSKPSPEKMSQEKKNQDFGNIFSFPSYSQKTDDDTTKLDSDEEDSTPVFSSPFAPKQTEKMLSKTVAAKKAKVDVPPKPKRAPKAKKMETVNSDSDSEFGIPKKTAAPKGKGRGAKKRKTSGSENEGEYNPGKKAPKSTPCKKSKKAAFDQDSDVEIFQSGFASETAPKPRTGRARKEVKYFAESDEDDDFDMFN
What is the function of this protein?
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.  Plays a role in B-cell differentiation.
What are the official names of this protein?
DNA topoisomerase 2-beta, DNA topoisomerase II, beta isozyme.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus.
Protein: GPDA_ECO45
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_CHLMU
Sequence: MTCDVSPLFGTDGIRGRANFEPMTVETSVLLGKAVAGVLLERHSGKHRVVVGKDTRLSGYMFENALIAGLTSMGIETLMLGPIPTPGVAFITRAYRADAGIMISASHNPYRDNGIKIFSSDGFKIGQAVEERIEAMIASKSFGGLPEDHAVGKNKRVKDAMGRYIEYAKATFPKGRTLKGLRIVLDCAHGAAYRVAPSVFEELDAEVICYGCEPSGCNINEGCGALWPSIIQKAVIEHEADVGIALDGDGDRLIMVDEKGHIVDGDMLLSICASDLKRRQALPENRVVATVMTNFGVLRYLESLGIQVTISPVGDRHVLQHMLETKAILGGEQSGHMIFLDYNTTGDGIVSALQVLRIMIESESTLSDLTACIVKSPQSLINVPVAKKVPLDSLSNVQVVLQEVKEILGDSGRILLRYSGTENICRVMVEGTKKHQVDSLAKTIVDVVEAEIGGAEISE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: GPX6_MOUSE
Sequence: MAQKLWGSCLFSLFMAALAQETLNPQKSKVDCNKGVTGTVYEYGANTIDGGEFVNFQQYAGKHILFVNVASFCGLTATYPELNTLQEELKPFNVTVLGFPCNQFGKQEPGKNSEILLGLKYVRPGGGYVPNFQLFEKGDVNGDNEQKVFSFLKNSCPPTSELFGSPEHLFWDPMKVHDIRWNFEKFLVGPDGVPVMRWFHHTPVRIVQSDIMEYLNQTSTQ
What are the official names of this protein?
Glutathione peroxidase 6, GPx-6, GSHPx-6.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PR1A_HORVU
Sequence: MSTSAVLFLLLAVFAAGASAATFNIKNNCGSTIWPAGIPVGGGFELGSGQTSSINVPAGTQAGRIWARTGCSFNGGSGSCQTGDCGGQLSCSLSGQPPATLAEFTIGGGSTQDFYDISVIDGFNLAMDFSCSTGDALQCRDPSCPPPQAYQHPNDVATHACSGNNNYQITFCP
What are the official names of this protein?
Pathogenesis-related protein 1A/1B.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: KDSA_PHOPR
Sequence: MMEQKTVRVGDIDVANDKPFVLFGGMNVLESRDLAMKICEHYVEVTNKLGIPFVFKASFDKANRSSVHSYRGPGMEEGLKIFQELKDTFGVKIITDIHEIYQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQYMSPGQVGNIVEKFAECDNENVILCERGALHGYDNLVVDMLGFDVMKKASKGSPIIFDVTHALQCRDPLGAASGGRREQTVDLARSGIATGIAGLFMEAHPAPDQARCDGPSAFPLDKLEPFLNQIKQLDDLIKGFEAIEIN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH21A_SAGOE
Sequence: MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKSSPRSTQGTTGIREDPDVCLKAP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7.  In SLAM signaling seems to cooperate with SH2D1B/EAT-2.  Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2.  However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1.  Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions.  Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation.  In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity).  May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 (By similarity).
What are the official names of this protein?
SH2 domain-containing protein 1A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_EUCGG
Sequence: MIIFNNLPSFFVPLVGLVFPAIAMASLSLHVQKNKIF
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YWQJ_BACSU
Sequence: MSKVFESKSLIEEAKSRKKQYETLEEQLNTLKKAFQGVADLGDNFKGNGADNIKDFFQGQAEIVDSWLTLVSAQIAFLNGISGDIKDQELNDSYVETSFLDHELPNGDLKASEIVSAHKEEIDSILSGISDIIDLDMYTLDDYADKMGDAQKIRRDTITAVDKLDESLTTEYQNLESLDNAVLTKYSVLMQATSNGKSASPMYYDKKAFHSNEVYKSVIEVENQGTTYIDAKTQQAEARRLQEKAEEEANKPWYEKTWDGVCNFTGEVTGYYDYKRATEGVDPVTGEKLSTAERVTAGAMAAAGFIPVVGWAGRAFKGGKAIYKTGKAAIAAEHALDAYKTGKSLDILKMTEMGAYGLVASNGFSEAVTGRDMFGNKVSEEKRKQGALEAITIIGGAGLAHYFDRLYQKNAPYVNKVSNESLISNIAKTTEEKQTRLQYLRNKHGVLSKEDLHHRINLRAEVLNELSRIKSSGLTKKQRGPAVAGVLDKKTGNYYFGINNIDGKPPKVLHPLIHDRIVNMPTELKEGYIKTSGAGSHAEVNALNEALLQRPDADLKDLMVYVVSARKINKKMPEGVPMPRCPHCEYITQNTNYIPEALKYGK
What is the function of this protein?
Toxic component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  Overexpression alone in situ causes growth arrest but not cell lysis; no effect is seen on DNA or rRNA.  Co-overexpression with cognate immunity protein YwqK does not cause growth arrest.  The toxic effect is dependent on the epsA and tapA operons which are required for biofilm formation (PubMed:34280190).  Its toxic effects are probably neutralized by its cognate immunity protein YwqK, but not by immunity proteins specific to other toxins with the LXG domain (Probable).  May have deaminase activity (Probable).
What are the official names of this protein?
Toxin YwqJ.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the LXG family.
What are the subcellular locations of this protein?
Secreted. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE.
Protein: YCF2_EUCGG
Sequence: MKGHQFKSWIFELREILREIKNSHHFLDSWTQFNSVGSFIHIFFHQERFIKLLDPRIWSILLSRNSQGSTSNRYFTIKGVVLFVVAVLLYRINNRNMVERKNLYLTGLLPIPMNSIGPRNDTLEESFGSSNINRLIVSLLYLPKGKKISESCFLDPKESTWVLPITKKCIMPESNWGSRWWRNWIGKKRDSSCKISNETVAGIEISFKEKDIKYLEFLFVYYMDDPICKDHDWEFLDRLSPSKRRNIINLNSRQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEPISHLFSRKKWAISLQNCAQFHMWQFRQDLFVSWGKNPPESDFLRNISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLKGSSDQSRDHFDSISNEDSEYHTLINQREIQQLKERSILWDPSFLQTERTELESDRFSKCLSGYSRLFTEREKEMKNHLLPEEIEEFLGNPTRSILSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDPGCDMVPKDELDMHSSHKISFLNKNTFFDLFHLFHDRNRGGYTLHHDFESEERFQEMADLFTLSISEPDLVYHKGFAFSMDSYVLDQKQFLNEVFNSRDESKKKSLLVLPPLFYEENESFYRRIRKKWVRISCGNDLEDPKPKIVVFASNNIMEAVNQYRWIRNLIQIQYSTYGYIRNVWNRFFLMNRSDRNFEYGIQRDQIGNDTLNHRTIMKYTINQHLSNLKKSQKKWFNPLIFISRTERSVNRDPNAYRYKWSNGSKNFQEHLEHFVSKQKSRFQVVFDRLRINQYSIDWSEVIDKKDLSKSLRFVLSKLLLFLSKFLLFLSNSLPFFFVSFGNTPIHRSEIHVYELKGPNDQLCNQLLESIGLQIVHLKKWKPLLLDDHDTSQKSKLLINGGTISPFFFNKIPKWMIDSFHTRNNRRKSFDNTDSYFSMISHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFCFYCNKRFPFYVERARINNSDFTYGQFLNILFIRNKIFSLCGGKKKYAFLERDTISPIESQVSNIFIPNDFPQSGDERSNLYKSFHFAIRSDPLVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLYQYLNFNSNMGLIHTPCSEKYLPSEKRKKRSLCLKKCVEKGQMYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNWIFLDTFSDLLPILSSSQKFVSIFHDIMHGSDISWQILQKKFCLPQWNLISEISSKCLHNLLLSEEMIHRNNESPLISTHLRSPNVREFLYSILFLLLVATYIVRTHLLFVSRAYSELQTEFEKVKSWMIPSYMMELRKLLDRYPTSELNSFWLKNLFLVALEKLGDSLEEIRGSASGGNMLWGGGPAYGFKSIRSKKKYWNINLIDLISIIPNPIHRITFSKKTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIDDKEREFLVQFSTLTTEKGIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRYLVDIHKKYLMNYEFNTFCLAERRIFLAHYQTITYSQTSCGTNSFHFTSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFLIDDIDIEDSDDIEDSDNIDRDLDTELELLTRMNALTMDMMPEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLSLGLLVNYLSRDCERCSTQNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNVRDLVALTNEALSISITQKKSILDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSIAQDLWSLPGPDEKNEITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDYSQFDNDRVTLLLRPKPRNPLDMMQNGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPWGFLFDCIERPNSLGFPYWARSFRGKRIIYDEKEELQENDSEFLQSGTMQYQTRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDSPTSIYKRWFIKNTQEKHFELLIHRQRWLRTNSSLSNGFFRSNTPSESYQYLSNLFLSNGRLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: YCF3_IPOPU
Sequence: MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQACNNMAVICHYRGEQAIQQGDSELAETWFDQAAEYWKQAIALTPGNYIEAHNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GCS2_SALEP
Sequence: MALNDFHVSEPYTLGIELEMQVINPPGYDLSQDSSTLIDAVKPQLTAGEIKHDITESMLEMATGVCRDIDQAAAQLSAMQHVILQAASEHHLGICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCANGDDAIYLLHGLSHFVPHFIALSAASPYMQGSDTRFACARLNIFSAFPDNGPMPWVSNWQEFAGLFRRLSYTTMIDSIKDLHWDIRPNPAFGTVEVRVMDTPLTLDHAINMAGLIQATAHWLLTERPFKPQEQDYLLYKFNRFQACRYGLEGVITDAYTGDRRRLADDTLRLLDNVTPSARKLGADSAIDALRLQVKKGGNEAQYMREFIADGGSLIGLVQKHCEIWAGQ
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: HEMN_HELPY
Sequence: MQTIDFEKFSQYSKPGPRYTSYPTAVEFNENFNEESLKTAFFNHDNLKNPMPLSLYTHLPFCRSACYFCACSVIYTSLEEKKIRYISYLKKELALLKNAMDTNREVAQFHYGGGTPTFFSPIQLDEITQSIQEVFPNFSKDIEMSCEIDPRHFTKEHMQTLFDRGFNRLSFGVQDFDFEVQKAIHRIQPFEMVQESVKLARDYGIKSINFDLIYGLPNQTKEGFLKTLEWVLKLDPDRLAVFNYAHVPWVKKTMRKIDETLLPSLRDKLEILESLISFLEKANYQMIGMDHFAKSDNELYLALQKAELRRNFQGYTTKKFTQTIGIGVTSIGEGGDYYTQNYKDLHHYEKALDLGHLPVERGVALSQEDVLRKEVIMQMMSNLKLDYSKIEEKFSVDFKAHFKKELEKLKPYEEAGLLSFNSKGFEMTKTGGMLVRNMAMEFDAYLRGGEKHFSKTL
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_CRYHO
Sequence: MAIGKNKRISKGRKGGRKKVVDPLSRKEFYDLRAPSTFKVRNFGTTIASKNQGTKLAVDALRHRVYEVSLADLNNDEDQAFRKIKLQCEDIQGRTCLTEFHGMDMTRDKLCSLIRKYQTLIEAHCNVKTSDGYVLRLFCIAFTRRMADQVKSTCYAQTSQIRQIRKKMVEIITAEAEGTTLRDLVKKFIPESIGKEIEKACRHIFPLQHVFIRKVKVLSKPSFDVSRLMESHVGADGVEEKGTKVVSESNQATNLLTAEMKA
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_STAEQ
Sequence: MAKNIAKALLDIEAVSLSPNDLFTWSSGIKSPIYCDNRITLGYPEVRNAIRDGLIQLIKEHFSNVEIISGTATAGIPHAAYISEKMELPMNYVRSKSKSHGKQNQIEGAKSENKNVVVVEDLISTGGSSITAVEALEEAGANVLGVVAIFTYGLAKADETFNKAHIPFYTLSDYNELIEVAKDDGKISLNDIQTLVDWRDNLS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.