PharMolix/UniProtQA huggingface dataset:
Protein: DAAM2_HUMAN
Sequence: MAPRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNREAMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQSLYAFDEEETEMRNQVVEDLKTALRTQPMRFVTRFIELEGLTCLLNFLRSMDHATCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISTIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKYTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPGGPPTPPGAPPCLGMGLPLPQDPYPSSDVPLRKKRVPQPSHPLKSFNWVKLNEERVPGTVWNEIDDMQVFRILDLEDFEKMFSAYQRHQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIRQAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELQHLPEAAKVNLAELEKEVGNLRRGLRAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALMHFGEHDSKMQPDEFFGIFDTFLQAFSEARQDLEAMRRRKEEEERRARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSRKRSGSQALEVTRERAINRLNY
What is the function of this protein?
Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system.  Acts downstream of Wnt ligands and upstream of beta-catenin (CTNNB1).  Required for canonical Wnt signaling pathway during patterning in the dorsal spinal cord by promoting the aggregation of Disheveled (Dvl) complexes, thereby clustering and formation of Wnt receptor signalosomes and potentiating Wnt activity.  During dorsal patterning of the spinal cord, inhibits oligodendrocytes differentiation via interaction with PIP5K1A.  Also regulates non-canonical Wnt signaling pathway.  Acts downstream of PITX2 in the developing gut and is required for left/right asymmetry within dorsal mesentery: affects mesenchymal condensation by lengthening cadherin-based junctions through WNT5A and non-canonical Wnt signaling, inducing polarized condensation in the left dorsal mesentery necessary to initiate gut rotation.  Together with DAAM1, required for myocardial maturation and sarcomere assembly.  Is a regulator of actin nucleation and elongation, filopodia formation and podocyte migration (PubMed:33232676).
What are the official names of this protein?
Disheveled-associated activator of morphogenesis 2.
What is the protein family that this protein belongs to?
Belongs to the formin homology family.
Protein: RLUB_XYLFT
Sequence: MSDTPKPPSNTLSLKRETATEAPKLEERLHKVLAQAGLGSRRALEQRISNGLIKVNGDIAQLGMSVKSGDKIELDGRSFVASALTEPARVLIYNKPEGEVTTREDPEGRPTVFETLPVLKGARWIAIGRLDINTTGLLLLTTDGELANAMMHPSSEIEREYVVRVRSPEGEEHVQDELLEQLTRGVMLEDGTAKFDTIERIGNTDSHDWFRVVVKEGRNREVRRLWESQGCQVSRLKRTRYGSVLLPRELLRGQSTELPKTQVEALRTQLKLEKDMPLALTLQPVIGQRRSAKATLHVNRNDNNKHAYHNNHSTADESRELRRFDTLRDDRGRGQGKHHFKDRLTVSGEAAAKQAHKPFKQYKPKNDRSLSEGSPATFQSWYVPEGVSTGPRNHRNAGAGNGAHPNKKSPNPNTRNTQGQQTRKSPYKYTNNAPNFPSDHATPTFNPYGNPGQKTGAGQPNNSGGKYNRNRGPRYP
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: GLND_SALHS
Sequence: MNTLPEQHANTALPTLPDQPQNPGVWPRAELTVAGIKARIDIFQHWLGEAFDSGICAEQLIEARTEFIDQLLQRLWIEAGFGQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDEQAQKVGELLTLLWDVKLDVGHSVRTLEECLLEGLSDLTVATNLIETRLLIGDVALFLALQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTPAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNDPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPVDDEFQLRGTLIDLRDDTLFIREPQAILRMFYMMVRNSAITGIYSTTLRHLRHARRHLSQPLCYIPEARTLFLSMLRHPGAVSRGLLPMHRHSVLWAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFAKEETRQRHPLCVDLWPRLPHPELILIAALFHDIAKGRGGDHSVLGAQDVLTFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTETRLRFLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEAALHKIWTRCRANYFVRHSPNQLAWHARHLLQHDLRQPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLAADRHDVIRTGLEQTITQRSWQPPQPRRQPAKLRHFTVETEVNFLPTHTDRKSFMELIALDQPGLLARVGQIFADLGISLHGARITTIGERVEDLFIIATADRRALNNVLQLEVQQRLTAALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MINY1_MOUSE
Sequence: MEQPQTENPAPSKATSAETVESENHEALSGPEKHPQDKDGADADGAAGEQEPGDQTLPPAQDGENLECPPPEASSSPPGPACGTSPKVETAEVCSRPQELPQSPRIQQPELDFYCVKWIPWKGERTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELLTHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSIFDLLGIPLYHGWLVDPQSPEAVSAVGKLSYNQLVEKIITCKHSSDSNLVTEGLVAEQFLETTAAQLTYHGLCELTAAATEDELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKSHGAEGGGGSPEKQLQVDQDYLIALSLQQQQQPQGTLGLSDLELAQQLQQEEYQQQQAVQPVRTRAPSPQGRGATSGRPAGERRQRSKTESDCVLL
What is the function of this protein?
Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins.  Has exodeubiquitinase activity and has a preference for long polyubiquitin chains.  May play a regulatory role at the level of protein turnover.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase MINDY-1, Deubiquitinating enzyme MINDY-1, NF-E2 inducible protein, Protein FAM63A.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
Protein: IFT22_CAEEL
Sequence: MATENPQTWALWLILSEMASDMQEDKKVAKILVLGPPKAGKTTLCTFLADFMEDGDTLKKGEDSGERERKFEFEFTSVYRPTKGVRIQEFETHEFFTEQEQNELGGTRRLEDSEIQLWDVSGDKKYEDCWPAIKENAEGVILVVNPEEHKGSDLQQWFYEFVEKENIDLSCVMVILNEQGAKKTNHEQISGFEILPKLRGVHHVAHHFGSEAMQVKMEVNSFMASVLKMDQRQMGSGVDHGLGYADEQEDDF
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium (PubMed:28479320).  May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility (PubMed:28479320).  Regulates specific signaling activities in the cilia, such as the daf-2/insulin receptor-like transduction pathway (PubMed:16968739).
What are the official names of this protein?
Intraflagellar transport associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Note=Moves along the axoneme.
Protein: CLPP_ANOFW
Sequence: MNLIPTVIEQTSRGERAYDIYSRLLKDRIIILGSPIDDHVANSIVSQLLFLAAEDPEKDISLYINSPGGSITAGMAIYDTMQFIKPDVSTICIGMAASMGAFLLAAGAKGKRFALPNSEIMIHQPLGGVQGQATEIEIAAKRILFLRDKLNRILSENTGQPIEVIERDTDRDNFMTAEKAKEYGLIDRVLTRVDEK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_BURVG
Sequence: MKLDLKILDARMRDYLPAYATTGSAGLDLRACLDAPVTLQPGETTLVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSTWNRGQSEFVLNPFERLAQLVIVPVVQAQFNIVDDFAQSERGEGGFGSTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PUR5_BRUSI
Sequence: MTMENKPAGQNGLTYAQAGVDIDAGNLMVEKIKPLVRSTRRPGADGEIGGFGGLFDLKAAGFKDPVLVAANDGVGTKLKIAIDADIHDTVGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLSPDQGVAIVSGIAEGCRQAGCALIGGETAEMPGMYRDGDYDLAGFAVGAAERDRLLPRGDIAEGDIILGLASSGVHSNGFSLVRRIVELSGLGWKSQAPFQPGATLGEALLTPTRIYVKPLLAAIRACDGIKALAHITGGGFPDNIPRVLPKGLAAEIDLPAIAVPPVFSWLAKTGNVEPNEMLRTFNCGIGMIAVVNPAKVDEVIAALAAEGEKVVTLGRMTRREKDGVIYKGQLAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_HELPJ
Sequence: MKLIASNKKAYFDYEILETLEAGLALLGSEVKALRQTRVNLKDNFVKIIKGEAFLFGVHISYLDTIHAYYKPNERRERKLLLHKKQLLKWQMEASKERLSIVGLKLYFNQKNRAKIQIALVKGKRLHDKRQSLKEKALNKEILADLKHHFKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LRFN2_MOUSE
Sequence: METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV
What is the function of this protein?
Promotes neurite outgrowth in hippocampal neurons.  Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A (By similarity).  May play a role in redistributing DLG4 to the cell periphery.
What are the official names of this protein?
Leucine-rich repeat and fibronectin type-III domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the LRFN family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Synapse. Postsynaptic cell membrane.
Protein: CHI2_PEA
Sequence: MSKLRIPILLVLFIVSCCSAEQCGTQAGGALCPGGLCCSKFGWCGSTSEYCGDGCQSQCSGSSGGGTLSSLISGDTFNNMLKHRNDNACQGKPFYTYDAFLSAAKAFPNFANKGDTATKKREIAAFLGQTSHETTGGWPTAPDGPYAWGYCFLREQNPSTYCQASSEFPCASGKQYYGRGPIQISWNYNYGQCGRAIGVDLLNNPDLVATDPVISFKTALWFWMTPQSPKPSCHDVITGGWTPSSADRAAGRLPGYGTVTNIINGGLECGRGQDSRVQDRIGFYKRYCDIFGIGYGDNLDCYSQRPFGSSLPLSSILLDTVAAA
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase A2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: RRF_COREF
Sequence: MIDEILFDSEERMSNTVEHTREDLITIRTGRANPAMFNGVLAEYYGVPTPITQMSSISVPEPRMLIIKPYEMSSMGVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRRDMVKIAKGKGEDGKIAIRNVRRKGMEQLKKLQKDGEFGEDEVAAAEKELDKITAHYVEQVDEIVARKEAELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_LISMF
Sequence: METIHFTKVHGSQNDFFLVDEEENHITEWSDEKRANFAIKLCDRKHSLGGADGILYVTKSSEVGPIGQMRVVNSDGSIASMCGNGLRTVARYLLEKHALTDAKVETMKAILDVKKATSLGFDIPTYQVEISPVKFAAETLPMHVGVEKLFNQVIPELDAELAFSAVSVPNPHLITFVDQAVLDSNKQEKLASYLNSENPYFPDGVNVSFVKRLSDDAIYVRTFERGVGFTNACGTAMSACSLIKKMLDNNILETPLNVYNDGGRVQVTAKKDAAGEISLQLIGNATFVSKGSVRYENDIVTELTNEATAEQAQYQALVKEVKEFLKTTE
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD166_CARAU
Sequence: MQSVVCLIGAFIAAAVFRPGSCVGTVIGLYGETIVVPCNDGTKKPDGLIFTKWKYVKDDGSPGDLLVKQAQKDEATVSATDGYKSRVSIAANSSLLIARGSLADQRVFTCMVVSFTNLEEYSVEVKVHKKPSAPVIKNNAKELENGKLTQLGECVVENANPPADLIWKKNNQTLVDDGKTIIITSTITKDKITGLSSTSSRLQYTARKEDVESQFTCTAKHVMGPDQVSEPESFPIHYPTEKVSLQVVSQSPIREGEDVTLKCQADGNPPPTSFNFNIKGKKVTVTDKDVYTLTGVTRADSGIYKCSLLDNDVMESTQFVTVSFLDVSLTPTGKVLKNVGENLIVSLDKNASSEAKVTWTKDNRKLDKLPDFSKLTYSDAGLYVCDVSIEGIKRSLSFELTVEGIPKITSLTKHRSSDGKHKVLTCEAEGSPKPDVQWSVNGTNDEVSYNNGKATYKLTVVPSKNLTVSCLVTNKLGEDTKEISVFSQKNEDGTEQAKVIVGIVVGLLVAAALVGLIYWIYIKKTRQGSWKTGEKEAGTSEESKKLEENNHKPDV
What is the function of this protein?
Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts.  Promotes T-cell activation and proliferation via its interactions with CD6 (By similarity).  Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (By similarity).  Mediates homotypic interactions with cells that express ALCAM.  Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction.  Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions.  Required for normal organization of the lymph vessel network.  Required for normal hematopoietic stem cell engraftment in the bone marrow.  Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow.  Promotes in vitro osteoblast proliferation and differentiation (By similarity).  Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM (By similarity).  Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
What are the official names of this protein?
CD166 antigen homolog, Activated leukocyte cell adhesion molecule, DM-GRASP homolog, Neurolin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Note=Detected at the immunological synapse, i.e, at the contact zone between antigen- presenting dendritic cells and T-cells. Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse.
Protein: MIAB_CAMJE
Sequence: MSAKKLFIQTLGCAMNVRDSEHMIAELTQKENYALTEDIKEADLILINTCSVREKPVHKLFSEVGGFEKVKKEGAKIGVCGCTASHLGNEIFKRAPYVDFVLGARNISKITQAIKTPKFMGVDIDYDESEFAFADFRNSIYKSYINISIGCDKHCTYCIVPHTRGDEISIPFNIIYKEAQKAIEKGAKEIFLLGQNVNNYGKRFRNEHKKMDFSDLLEELSTIEGLERIRFTSPHPLHMDDKFLEVFANNPKVCKSMHMPLQSGSSEILKAMKRGYTKEWYLNRALKLRELCPNVSISTDIIVAFPGESEKDFEETVDVLEKVRFEQIFSFKYSKRPLTKAATMPNQIDEEIASRRLSTLQNRHSEILDKIVKKQENKTFKVLFEELRAGNSIAGRTDNNFLVQVEGSEELLGQFKEVKITNAKRMVLYGEIV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_SHEHH
Sequence: MNILLANPRGFCAGVDRAISIVERALELFSPPIYVRHEVVHNRYVVQNLKDRGAVFVEELDQVPDESIVIFSAHGVSQAVRHEAKRRGLKVFDATCPLVTKVHLQVARASRKGIECILIGHAGHPEVEGTMGQYDNPAGGVHLVESPEDVANLVVKDPDNLCFVTQTTLSMDDTTDVIASLQSKYPSIEGPRKDDICYATQNRQDAVRNVAEKVELFIVVGSKNSSNSNRLRELAQKKGTTAFLVDNADDVDPSWFNGIQHVAVTAGASAPEVLVKQVVDAIAKMAPSVITEVEGRLEDTVFAVPAELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PSTB_EDWTA
Sequence: MSNVVTDPTNSKIQVRDLNFYYGKFHALKNISLDIEKNKVTAFIGPSGCGKSTLLRTFNKMFQLYPEQRAEGEILLDGQNILTDSQDVALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWSETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTSRIEELITELKQDYTVVIVTHNMQQAARCSDYTAFMYLGELIEFSDTDKLFTAPAQRQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Peripheral membrane protein B, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPF_LEGPH
Sequence: MDINLTLIVQMLVFAAFVLFTMKLVWPPLAKALEERQDKIADGLAAAERGRKELELAQHRVKDELKQAKAHSADIIDKANKRASEIIEAAKEAAKREAQIQAKLAQEQIAQQVNHAKEELRKQVAKLAITGAEKILMREVDAKANSELLDNLIEEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BCHN_CHLCH
Sequence: MMQGIGGDIQDSQLIREDNVTHSFCGLACVGWMYQKIKDSFFLILGTHTCAHFLQNALGMMIFAKPRFGIALIEEGDLAKNEPTLQEVVSEIKADHHPSVIFLLSSCTPEVMKVDFKGLADHLSTPETPVLFVPASGLVYNFTQAEDSILSALVPYCPQAPAGEKKVVFLGSVNDSTAADIRADAEELGIPVGGFLPESRFDKMPAIGPDTVLAPIQPYLSRVALKLSRERGSTVLHSLFPYGPDGSRVFWEDLAREFGITVDLREREAAAWEKIRKQTDKLKGKKVFLTADTMLELPLARFLRHAGADIMECSSAYIIKKFHAKELEALQGVRVVEQPNFHRQLEDIRRERPDLIVTSLMTANPFVGNGFVVKWSMEFMLMPIHSWSGVVSLANLFVAPLQRRSMLPAFDESVWLEGAMPSAEVHA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: VP9_RRSVT
Sequence: MKTAFARDPFTAPATGTYGTIYASRSLPRLSISKFLEDANPEIYELSRYEALGTNRPSSGKRAMQPAVSKPALLETVFTLDIWYRRTNNQNIGNLRDSVSRFLSDDRVREAVMVRLDLDIVVQLKEYWLIVKDKEAQTFADRLAFDSHLFVNRGENANYDLVTQTFIPSDTFLKDNFKTEALKKLLLSVQSHTGLDAGLQGDSSKATYNIGLGQYLEDEALLYRQGVALQQMAFAELELARGAEKEAFPSTFDLSNRPACNLILKRTCKWYQQTFKAEERKEFAKSLWVDDFAEANWNTGNLSFGFSTTLNVIERWRLTRFYVHMYSSVHIYSQKASG
What is the function of this protein?
Plays an important role in virus transmission by the insect vector.  May participate in the virus stability by binding clamp proteins and surrounding the pentameric turrets present in the virion.
What are the official names of this protein?
Structural protein VP9.
What are the subcellular locations of this protein?
Virion.
Protein: RL34_BORBR
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRAGRAILNARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: UBP30_DANRE
Sequence: MPWCKQGTTDKLVREFLRTGAAARNKMMKNWGVIGGIAAAMAAGVYVLWGPISDRRKKRKGMVPGLLNLGNTCFMNSLLQGLAACPSFIRWLEDFTSQNSADRERTERETQLSRSLMQLLKALSSHDPGEDDVLDAGGLLEALRLYRWHISSFEEQDAHELFHVLTSSLEEEQERQPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYMACKRCEQQSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVECENCTKQQAGELVNGEVLESQRTTFVKQLKLGKRLTWSKEGSPIKRQEHVQFTEYLSLDRYKHCSAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKPQSNGTFPSVFLHSPGLSSQLNLTYDYSTSEYLFRLTAVLVHHGDMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRKASLQEVLSSSAYLLFYERMQRPGLRVEE
What is the function of this protein?
Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 30, Deubiquitinating enzyme 30, Ubiquitin thioesterase 30, Ubiquitin-specific-processing protease 30, Ub-specific protease 30.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: NADA_ECO81
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEVYVDERLLERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.