PharMolix/UniProtQA huggingface dataset:
Protein: G3P_MYCTU
Sequence: MTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRVPIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVTLVGKSL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICP0_BHV1K
Sequence: MAPPAAAPELGSCCICLDAITGAARALPCLHAFCLACIRRWLEGRPTCPLCKAPVQSLIHSVASDECFEEIPVGGGPGADGALEPDAAVIWGEDYDAGPIDLTAADGEAPGAGGEAGAAGGSEAGGGAGGAEAAGEARGAGAGRAAGAAGGRAGRGADAAQEFIDRVARGPRLPLLPNTPGHGPGAPYLRRVVEWVEGALVGTFAVTARELAAMTDYVMAMLAECGFDDDGLADAMEPLIGEDDAPAFVRSLLFVAARCVTVGPSHLIPQQSAPPGGRGVVFLDTSDSDSEGSEDDSWSESEESSSGLSTSDLTAIDDTETEPETDAEVESRRTRGASGAARARRPAERQYVSTRGRQTPAVQPAPRSLARRPCGRAAAVSAPPSSRSRGGRRDPRLPAAPRAAPAAQARACSPEPREEGRGAGLGVAAGETAGWGVGSEEGRGERRAKLLGEAGPPRVQARRRRRTELDRAPTPAPAPAPAPAPISTMIDLTANAPARPADPAPAAALGPALAGAQIGTPAAAAAVTAAAAAPSVARGSAPSPAVTAAATGTAAAISTRAPTPSPAGRAPAADPRRAGAPALAGAARAEAGRNGNPGRERRPASAMARGDLDPGPESSAQKRRRTEMEVAAWVRESLLGTPRRSSAALAPQPGGRQGPSLAGLLGRCSGGSAWRQ
What is the function of this protein?
Evades nuclear antiviral defenses triggered by dsDNA viruses.  Acts during the initial stages of lytic infection and the reactivation of latent viral genome.  Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100.
What are the official names of this protein?
E3 ubiquitin-protein ligase ICP0, IER 2.9/ER2.6, P135 protein, RING-type E3 ubiquitin transferase ICP0.
Protein: RL27_FRACC
Sequence: MAHKKGASSSRNGRDSNAQRLGVKRFGGQYVKAGEIIVRQRGTHFHPGDLVGRGKDDTLFALSPGHVRFGHRRGRRVVNVVAEAAVPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RADA_PYRCJ
Sequence: MSTRKKKADAEVAQAATVAASPDIDVEELEGIGRVTGAKLKEKGYYTVRDVAYASVKELAEIVGSEERAQQIVEAARKMLGLHSFISALEVYERRKKIRRISTGVRALDELLGGGIETRAVTEVVGEFGSGKTQLCHQLAVMVQLPEDRGGLGAKAIYIDTENTFRPERIMQIAKARGLDPDQALNNIFYARAYSADHQMVLVEQAKSLIRQHNVALLVVDSVIAHFRAEFPGRENLAERQQKLNKHIADLLRLADAYDVAVVVTNQVMAQPDVFFGNPLRPAGGNILAHGATYRLWLRKSKENIRIAKIFDSPYHPEGEVSFRITEEGLVD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: GRPE_ALKEH
Sequence: MSDKQREAERQQSEDKAHSEAESAEAGQAPEAQAAEDGAESASGDSGDELTELQQALEEARARAEENWNECLRARAEMQNIQRRAQADVEKARKYAVEKIAGDLLGVKDSLEMGVKAAKEEGADPQKLLEGSELTLKMLSQVLERFNVQEIDPQGERFNPEHHEAVAAQPSHEHEPNTVLNVMQKGYALHDRVLRPAMVVVSQKAPEPPPSGSIDEQA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_PSEAE
Sequence: MSLDFLPFSRPSIGEDEIAAVEQVLRSGWITTGPKNQELEQRFAERLGCRHAVALSSATGALHVTLLALGIGPGDEVITPSLTWVSTANVITLLGATPVFVDVDRDTLMCSAQAVEAAIGPRTRAIVPVHYAGSTLDLEGLRTVAGRHGIALVEDAAHAVGSEYRGRPVGSRGTAIFSFHAIKNLTCAEGAMFVSDDSALAERVRRLKFHGLGVDAYDRLSHGRKPQAEVIEPGFKYNLADLNAALALVQLKRLDALNARRQALAERYLERLAGLPLAPLGLPAHKQRHAWHLFILRIDAEVCGLGRDAFMEALKARGIGSGIHFIASHLHHYYRQRQPRLSLPNSEWNSARLCSIPLFPDMRDDDIERVARAIEEILEKRR
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: KDPB_BACC0
Sequence: MMRPVVVKEKRVNESHIHAVEDEVRQAKTMDRDIVKHAMKQSVAKLNPKVMIKNPIMFVVEIGFVITFILSFFPSHSSSIPGWFNITVSLILLFTVLFANFAEALAEGRGKAQADSLKQSKKDVFANVVKENGEIVQVSATDLRKDDVVIVKQGEMIPSDGEVIKGLASVDESAITGESAPVIKEAGGDFCSVTGGTMVVSDEITIVITSNPGESFIDKMISLVEGAARQKTPNEIALNTVLTSLTLIFLIVVVTLPIFTNYLGFQIDTAVLVALLVCLIPTTIGGLLSAIGIAGMDRVTKFNVLAMSGKAVEAAGDINTIILDKTGTITFGNRMAHTLLPVGNETIEQVGKWAAISSVLDETPEGRSVIEHVQAKSISYNKELAEQGEFIPFKAETRMSGVDLQDGTKVRKGAVGSVIEWVKSQGGTIPKDVNQKADFISKEGGTPLVVAVDNRIYGLIYLKDTVKPGMRERFEQLRQMGIKTVMCTGDNPLTAATIAKEAGVDEFVAECKPEDKIAVIKAEQDKGKLVAMTGDGTNDAPALAQADVGLAMNSGTTAAKEAANMIDLDSNPTKIIEVVGIGKQLLMTRGALTTFSIANDIAKYFAIIPAMFTLAIPQMEALNIMKLTSPLSAILSALLFNAVIIPLLIPLAMKGIAYKPMSSNALLGRNLLIYGLGGVIVPFIGIKVIDIIVGLFI
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYBG_DICDI
Sequence: MNNQLVPQNAAAAAAAAAAAAAAAAANSLKSRKPYTISKQRENWTDEEHQKFLEALTLFDRDWKKIESFVGSKTVIQIRSHAQKYFIKVQKNNTGERIPPPRPKRKSIQPYPQKQKHDGMGAFIPDSLSGNHFISSSSFATWMTYRGLMPNISESQINPSDLQKQLEQLQQAQQYIQQAVTTAQSSQRNGGLPPNPSSNNGGTTLTPNFPKIYAFLSNLFESNGTSFTEALSDLSMIDRETMQILMHNLAINLANQQYRDNHQTLSEQYRMKRDEDEDLNAIMISPRNSTGNINVSGDFYDNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGDFGDQNHSNMVNLGNYYNNHPNQNTINALYSLNQPSTLSNNPLNMVGNLNPQKQPPFNLNLNMQSGF
What are the official names of this protein?
Myb-like protein G.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_RUEPO
Sequence: MSRVKGGTVTHARHKKVLKAAKGYYGRRKSSFKVATQAVDKANQYATRDRKARKRNFRALWIQRINAAVRSHDEALTYSRFINGLNLAGIEVDRKVLADLAVHEPEAFGAIVAQAQAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NANR_SALSV
Sequence: MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQSLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNLSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQKMR
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: FER_GLEJA
Sequence: AIFKVKFLTPDGERTIEVPDDKFILDAGEEAGLDLPYSCRAGACSSCTGKLLDGRVDQSEQSFLDDDQMAEGFVLTCVAYPAGDITIETHAEEKL
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EXOC7_DANRE
Sequence: MIPTEDASARKREIEEKLKQEQETLSFIRESLEKSDQLTKGMVSILSSFESRLMQLENSIIPVHKQTENLQRLQENVDKTLSNMDHVISYYHVAKDTDKIIREGPAGRLYEYLACIAKIQKAVEYFQDNNPDSPELNTVKARFEKGKELLEAEFRSLLTRYSKPVPPVLILDAIGGDEDMEVQEEVTLEHLPEAVLQDIICISAWLVEYGRNQDFMNVYFQVRSSQLDRSIKGLKEHFRKNSATSAIHSPAVQTKRKETPTKKAPKRPVYIPGTIRKAQNLLKQYSQHGLDGKKGSNLTPLEGFEHDLRGVKHLSDEKHGATAGKDDVLDIEIDSYIHCISAFVKLAQSEYALLTEIIPEHHQKKTFDSLIQEALDNLMLEGDNIVSAARRAIMRHDYSAVLTIFPILRHLKQTKPDFDATLQGTAASTKNKLPALITSMETIGAKALEEFADSIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQVLGDTYNIPLDPRESSSSASSYSSEFSRKLLSTYIYKVLGNLQLNLSNKAKVYEDPALRAIFLHNNYNYILKSLEKSELIQLVAVTVKKVESSYRELIEQEIQNYQRSWLRVTEHLAERNIPDFQPGAKLKDKERQIIKDKFKGFNDGLEELCKIQKGWAVPDKEQRDTIRHAQKRVVSLTYKAFLQRCANISFTKNPEKYHRYSPEQVEDMIDRLFDTSA
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (By similarity).  It is required for neuron survival and plays an essential role in telencephalon development (PubMed:32103185).
What are the official names of this protein?
Exocyst complex component 7.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Midbody, Midbody ring.
Protein: RS17_ACTP7
Sequence: MTDKIRTVQGKVVSDKMDKSFVVAIERTVKHPLYGKFIRRTTKLHVHDENNEAKLGDVVEIKECRPVSKTKSHTLVRVVEKAVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ALSC_ECOLI
Sequence: MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSPEYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGVDPFLAAMIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGKGRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK
What is the function of this protein?
Part of the binding-protein-dependent transport system AlsBAC for D-allose; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
D-allose transport system permease protein AlsC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YNFE_BACSU
Sequence: MDEILKQYMVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQLQQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF
What are the official names of this protein?
Uncharacterized protein YnfE.
Protein: Y1349_HAEIN
Sequence: MSKTSIGLDKVQSAELADKLNELLATYQVFYTNVRGYHWNIKGVNFFALHAKFEEIYTNLVARVDEVAERILTLGYTPNNAYSQYLKISRIKEDIAVSEAQECLSGTLQGLKTLLDQQREILAFANNANDEGTASQMSDYIKEQEKLVWMFQAACQTCHN
What are the official names of this protein?
Uncharacterized protein HI_1349.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
Protein: NOVQ_STRNV
Sequence: MPALPMNQEFDRERFRVDLRATAAAIGAPVTPRVTDTVLETFRDNFAQGATLWKTTSQPGDQLSYRFFSRLKMDTVGRAVDAGLLDGTHPTVPIVEDWSDLYGGTPVQSADFDAGRGMAKTWLYFGGLRPAEDILSVPALPAPVQARLKDFLGLGLAHVRFAAVDWRHRSANVYFRGQGPLDTAQFARVHALSGGTPPAADVVAEVLAYVPEDYCVAITLDLHTGAIDRVCFYALKVPKDARPRVPARIATFLEVAPSHDPEECNVIGWSFGRSGDYVKAERSYTGNMTEILSGWNCFFHGEEGRDHDLRALQDTGSITGGAR
What is the function of this protein?
Magnesium-independent aromatic prenyltransferase that catalyzes the irreversible transfer of a dimethylallyl group to 4-hydroxyphenylpyruvate to produce the ring A structure in the novobiocin biosynthesis pathway.  Novobiocin is an aminocoumarin family antibiotic that targets bacterial DNA gyrases.  It is able to prenylate many different compounds, including the phenylpropanoids 4-coumarate and caffeate, the plant polyketide resveratrol, the (iso)flavonoid naringenin, apigenin, daidzein and genistein, and the dihydroxynaphthalenes 1,6-DHN and 2,7-DHN.
What are the official names of this protein?
4-hydroxyphenylpyruvate 3-dimethylallyltransferase, 4HPP 3-dimethylallyltransferase, Aromatic prenyltransferase NovQ, Dimethylallyl diphosphate:4-hydroxyphenylpyruvate dimethylallyl transferase, Novobiocin biosynthesis protein Q.
What is the protein family that this protein belongs to?
Belongs to the aromatic prenyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y619_PSEPW
Sequence: MSEPDVKSHKIEFPCADYPIKVIGDTVVGFKDMVIEVLSKHAKVDLATLAERQSKEGKYTTVQLHIVAESENQLHDINSALRATGIVKMVL
What are the official names of this protein?
UPF0250 protein PputW619_0619.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: PRSA_HALH5
Sequence: MKKRHLLIAGLACMTILGACNNDDAGSSGQAVVEVDGHEISDAEFVDMLKERYGEAILQELVQRHLISQAADSVEIPQEEIDEELETFKSQIGVETDDEMLDALSNQFGITVENKEEFVNEYILPPLVLEKLAVEGVEITDEEKQAYFDENRDSLIEVEASHILVEDEETAEEVLDRLEAGDDFAELASEYSVDPSAEANNGDLGFFGKGDMVPEFEEAAFNMEIDEVSEPVESTYGYHIILVTDRKDSYEELEEKIHDTLMRERSRTQEEVLRDLLAQADINVLDDQFEGLFDLPDAPPVEDTPEIDGEDASDEAEDQAEDADENAEEEDES
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
Protein: EFP_LAWIP
Sequence: MYSTTDFRKGLKIEIDGVPYDIIDFQHFKPGKGGAMVRTKLRNILNGRVIDNTFRSGEKVERPNLESRDMQFLYHEGSELIFMDLTNYEQLHMSEDVTNGKSEFLKDGQQCRVLLYNEKPIDIDIPLTLILEVIETETAIKGDTVSNVTKPAKLETGVVIQVPIFINIGERIKVDTRTKEYIGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_STRPZ
Sequence: MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGGVVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFAWANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETRDDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSAFINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQGLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQFPDSFVIN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_ANSSE
Sequence: VATVDCSEYPKPACTLEYMPLCGSDNQTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_RHIEC
Sequence: MKLFFRIVTLVAVVAMSLADMAPAWALTSRIKDIASLQAGRDNQLIGYGLIVGLQGTGDGFRSSPFTEQSMRAMLQNLGISTQGGQSNAKNTAAVMVTANLPPFASPGSRLDVTVSSLGDATSLRGGTLVMTSLSGADGQIYAVAQGSVIVSGFQAQGQAATVTEGVTTAGRVPGGAIIERELPSHFKDSVNLVLQLRNPDFSTAIRIADIVNGYASARFGGPVAEAKDSQEVVIQKPRTADLTRLMADVENLIVETDTPAKVVINERTGTIVIGSDVRVSPVAVSYGTLTVQVTETPQIIQPEPFSRGRTAVQPQTDIAAEQTGGRVAIIDGPDLRTLVAGLNNIGVKPDGIIAILQGIKSAGALQAELVLQ
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: DLTC_STRZT
Sequence: MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVEIENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_SHEPW
Sequence: MKQRQFFGTDGIRGKVGAGKMTPELALKLGWAAGRVLSRAGTHKVIIGKDTRISGYLFESALEAGLSAAGLDVMLIGPMPTPAVAYLTRTFRAEAGIVISASHNPYYDNGIKFFYTDGSKLEDAVELEIEAELEKPLTCVESHLLGKVGRIDDAAGRYIEYCKSHFPAEQTLSGLKIVVDCAHGATYHIAPSVFKELGAEVIAIGDKPNGLNINDKVGATSMAKICETVLEENADLGIALDGDGDRIMMVNRHGRVIDGDEILYILACDAQKRGVLQGGVVGTLMSNLGLDLALQALDIPFVRSKVGDRYVMELLKEHDWKIGGENSGHILNLDHGTTGDGIVAGILVLAAMCRQSASLEELTAGITMLPQVLVNVRFEGADDPLSSEVVLAAKAEVEQKLGARGRVLLRKSGTEPLLRVMVEGDDRADVTQFANDIADAVRNLV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CD4_CANLF
Sequence: MNQEAAFRHLLLMLQLVMLPAVTPVREVVLGKAGDAVELPCQTSQKKNIHFNWRDSSMVQILGNQGSFWTVGSSRLKHRVESKKNLWDQGSFPLVIKDLEVADSGIYFCDTDKRQEVELLVFNLTAKWDSGSSSGSSNIRLLQGQQLTLTLENPSGSSPSVQWKGPGNKSKHGGQNLSLSWPELQDGGTWTCIISQSQKTVEFNINVLVLAFQKVSNTFYAREGDQVEFSFPLSFEDENLVGELRWQAQGASSSLLWISFTLENRKLSMKEAHAPLKLQMKESLPLRFTLPQVLSRYAGSGILTLNLAKGTLYQEVNLVVMRANSSQNNLTCEVLGPTSPELTLSLNLKEQAAKVSKQQKLVWVVDPEGGTWQCLLSDKDKVLLASSLNVSSPVVIKSWPKFLAITLGGILGLLLLIGLCVFCCVKCWRRRRQAERMSQIKRLLSEKKTCQCSHRIQKTCSLI
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex.  The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.  In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway.  Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
What are the official names of this protein?
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts.
Protein: IFNG_PIG
Sequence: MSYTTYFLAFQLCVTLCFSGSYCQAPFFKEITILKDYFNASTSDVPNGGPLFLEILKNWKEESDKKIIQSQIVSFYFKFFEIFKDNQAIQRSMDVIKQDMFQRFLNGSSGKLNDFEKLIKIPVDNLQIQRKAISELIKVMNDLSPRSNLRKRKRSQTMFQGQRASK
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQHA_SALPA
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.