PharMolix/UniProtQA huggingface dataset:
Protein: CALM_MYXGL
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVNADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
What is the function of this protein?
Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding.  Calcium-binding is required for the activation of calmodulin.  Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: NAS7_CAEEL
Sequence: MLLPWIITIVTVIPATLGHRNRVQDDEMLVISDSTDSLNLEDFEFADKLTREELFGKHIPVEVVNDFKSDIRLPRRHKRNGVSRAAKLWPNARIPYAISPHYSPHERALLAKAVKQYHEKTCIRFVPRQTGEPDYLFIGKVDGCFSEVGRTSGVQVLSLDNGCMEYATIIHEMMHVVGFYHEHERWDRDNFIDIIWQNIDRGALDQFGKVDLSKTSYYGQPYDYKSILHYDSLAFSKNGFPTMLPKVKSATIGNARDFSDVDISKINRMYNCPVEKSVTAPFARARHVPIYSPQYHKYEDRPKIPLRSFDMQQGPINPPMAQIPSQSLVVSSSSGRVNYNSNKPSSQCEDRITVCWWTADRCRSPAIYQVMSSLCPKTCKFC
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-7, Nematode astacin 7.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM1_HELPS
Sequence: MELETHLSKYFTLAFTHKSMGLEMREKLAINSSATLKEFLQTIKNHCPNIKECMVLSTCNRFEIYASLKHGAHANEQKSALLKILAQNKKMSVSDLEKCVLMSVDESAVHHVFSVCSSLDSLVVGETQITGQMKNAYKFAFEEKFCSKDLTRLLHFAFKCAAKVRNLTGISKQGVSISSVAVKEALNIFEKERIKDKKALVIGLGEMAQLVIKHLLNKQFEALILGRNEAKFEDFIKELEEPKKVSFQNIENLNAYINEYQLLFCATSSPHFIVQNDMLKETIFRRFWFDLAVPRNIEKPVLDNIFLYSVDDLEPMVRENVENRQESRTKAYEIVGLATMEFYQWIQSLEVEPLIKDLRELARISAQKELQKALKKRYVPKEYESNIEKILHNAFNTFLHHPTIALKKNAQKEESDVLVGAIKNLFNLDKSSANHAQNLNLYKCEYYEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MURC_BRUSI
Sequence: MKMPLNIGLVHFIGIGGIGMSGIAEVLHNLGYKVQGSDQSDSANVQRLREKGIEVFVGHKAENLGDAEVIVVSTAIKKNNPELVAAREKLLPVVRRAEMLAELMRFRRAVAIGGTHGKTTTTSLVAALLDAGHLDPTVINGGIINAYGTNARMGDGDWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQALVSRIEDRRIITYGSNPQAEVRFVNQRMDGAASLFDVVIRSRKGEATEIKDLRLPMPGLHNVSNATAAIAVAHELGISSDDIRRGLGSFGGVKRRFTHTGSWNGVEIFDDYGHHPVEIRAVLKAAREATSQAGGRVVAIVQPHRYTRLASLFDEFAACFNDADTVIVAPVYTAGEEPIEGVNSEELVSRIKTAGHRDARYATGPEALAPLVASIAQAGDFVVCLGAGNVTQWAYALPKELAEQGKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_METBU
Sequence: MRIGVIAIQGDVSEHVESLERALAERGATAEIVNIKHKGIVPTCDGLVFPGGESTTLGRLILREGIDAEIKDAKEQGIPIMGTCAGLILTAKAGDSQVEKTHQHLLGLMDIKVNRNAFGRQFQSFEVGLEISFLDSPYNAVFIRAPAITEAGEGVKVLASIDGKIVAAEQDNVLAFAFHPELTDDMRVHQYFLDKLFN
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: KDKA_PHODP
Sequence: MQIIQTKQQYICYNPELLTETPEMAFSSEFWQQQNKIIGSAQGRGTTWFVQGEKLAMALRHYRRGGLFGKLVADSYLFSGWDKTRSVAEFSLLNHLIAHQVNVPKPVAARAVRLGWFRYQADILVEKIANSRDLVGILGQETLSQQVWFDVGAMIKRMHDAGVCHTDLNCHNIILDDHKTVWIIDFDKCYRLEGANWQEKNLARLHRSFIKEQGKRGILFNEDNWQWLCKVIRVNGNKGQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSBF_CHLVU
Sequence: MTARKSYTYPIFTVRWLAVHALAVPTVFFLGAITAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FMT_LEPIC
Sequence: MKIGYFGTPEHSAKLLEALIDSQLTEVLFVVTNPDRPKGRSKIPEPGPVKKKALEYNIPVFQYESIKKEKEKALSDFGLFSADLYVVFAYGSILPKEVYAHSTLTSINLHGSLLPDLRGASPVQTALWKGYTKTGITIQYIGEKMDEGDILLTKEVEIAPEDNTGTLMDKITDAGIESILQLLKTYDGKPFPSVPQAHDKATYCGKIKSEDRILDWSLKSEELHNRIRALYPDMIATTTFRDKRMNILKTKPSSLSLEINPTPGKLKRLDKKRLLTQCGDGRFLEILELQPENKNRMTASDFLNGFRIQEGETFG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: BARS1_STRVG
Sequence: MTDRQGLLTDRIALITGASSGIGAAQRGLFAREGAAVVVTARREERLAGLVDELRAQGARAAYVVADVTRSEDAVRAVEFTVERFGRLDAAFNKRRHGAGRTPLHLMDDPVYDDIMDTNVRGVFNCLRPEIAAMLASGAGGSIVNTSSTGGLVATPVAAPYVVSKHAVLGLTKGPAAEYGAHGIRVNAIAPGTTRSEMVADWFAQNPDAEELLHRATPQPRTAEPQEIAEAAAWLCSERASFVTGSTLVVDGGFTIL
What is the function of this protein?
Involved in the biosynthesis of virginiae butanolide (VB), which regulates the production of antibiotic virginiamycin.  Catalyzes the reduction of 6-dehydro-VB-A to VB-A, the last catalytic step in VB biosynthesis.  In vitro, can use various synthetic A-factor-type analogs.
What are the official names of this protein?
A-factor type gamma-butyrolactone 1'-reductase (1S-forming), 6-dehydro-VB-A reductase, Butyrolactone autoregulator synthesis.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TBL18_ARATH
Sequence: MAFGSPRNNSILAAAGFPRKVSTVAIAIGGLASFFVFGLLLRLSYPNSSSVGGIFYGIGNPEQVHVPLSLSNHTVNILQKSSDINAFDKNLTSDSSSGLPVVVSKSIPPPDFSSDRKLETPLTQEKEDLVSSDITEKTDVQSGERETNVSKAEDTPSASSPPDDVSETASAEPECDLYQGSWFYDPGGPLYTNNSCPVLTQMQNCQGNGRPDKGYENWRWKPSQCELPRFDARKFLELMKGKTLAFIGDSVARNQMESMLCLLWQVETPVNRGSRKMQRWYFKQSSVMIARIWSSWLVHQFNEKFDYAPEGVTKLKLDLPDERIMEAIPKFDVVVLSSGHWFAKQSVYILKEEIVGGQLWWPDKSKPMKVNNVDAFGISVETILKSMATHPNYSGLTIVRTFSPDHYEGGAWNTGGSCTGKEEPILPGKLVKNGFTEIMHEKQATGYNQAVDKVAENLKLKLKLMDITEAFGYRHDGHPGPFRSPDPNKITKRGPDGRPPPQDCLHWCMPGPVDTWNEMVLELIRRDRKSSST
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 18.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL2_BARHE
Sequence: MALKQFNPTTPGQRQLVIVDRSCLYKGKSVKTLTEGLSSKGGRNNRGRVTARFQGGGHKRSYRFVDFKRFKRDVPAKVERLEYDPNRTAFIALIRYEDGQLSYILAPQRLDVGDSVIAGSNVDIKPGNAMPLGNMPVGTIIHNVEMKPGKGGQIARSAGAYAQLVGRDQGMAILRLNSGEQRLVSSGCFATVGAVSNPDHANINDGKAGRSRWRGRRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGKPTKGKRTRSNKATDKFIMRTRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RML9_SCHPO
Sequence: MSIMKPTTRFFRFNSLELAVSPFQRIYGQLRFLRKQPKPFLVKLLNNEVSKLGRQGDVVSVTRGYYRNTLFPKKQAIAVDALKSMKAHLLQGSEFSTKTKE
What are the official names of this protein?
Probable 54S ribosomal protein L9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYGA_PEDPA
Sequence: MNKKLSVQEIILTLQKYWAEQGCMLMEAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLGSLKALGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEVTQFTYFQQVGGLEVNPVTSEVTYGLERLSSYIQDVESVFDLEWGNGVSYGDIFREPEFEHSKYSFEESNQAMLEKMFNDFEAEANRLIEEGLVHPAYDYILKCSHTFNLLDARGTVSVTERAGFLSRIRNMARKVARAFVEEREKLGFPLLKNNEEEAK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1581_MYCBO
Sequence: MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVPPNTGNLRDDLLRLGELICREVGQHASTIRAVLVEVSRNPALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQDTVQALVDDVILPSLTRSTG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb1581.
Protein: TPBGL_MOUSE
Sequence: MAPRAGQRGLWSPLPGLLLLAAALSRPAAPCPFQCYCFGSPRLMLRCASGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGGEGATDGVRLPLLTALRLTHNNIEVVEDGAFDGLPSLAALDLSHNPLRALGYRAFRGLPALRSLQLNHALARGSPGMLDALDAALAPLAELRLLGLVGNALSRLPLAALRLPRLEQLDARVNALAGLGPDELSALERDGDLPQPRLLLADNPLSCGCTSRPLLAWLHNATERVPDARRLRCASPRVLLDRPLIDLDEARLGCSDGDAHESGEGIDVAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQRWMHNLREACRDQMEGYHYRYEQDADPRRAPAPAAPAGSRATSPGSGL
What are the official names of this protein?
Trophoblast glycoprotein-like.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AATIR_AQUAM
Sequence: MKNRSYEYDVALSFAGENRAYVERVANSLKTKGVKVFYDLFEEANLWGKNLYEYLSEIYQNKARYTVLFVSSFYNKKLWTNHERVSMQARAFQESREYILPARFDDTEIPGILKTIGYINLENRTPEELAVLIENKLKKDQTFFKNRWSKLSTMISPKPFIFTIKVVDEKSQLVKHAKVVLVANNSTYLEGYTDENGLAHFVIRTRKLYTVLIAHSEYPAVVFKSMNPKEDIEVTIEKTNNSGSVIINKSGQIPGISGKIEPVLKSDKNLSVYADNIAIEGGKDQPYDFELNKSIVLEDNKGNIVHLTFRFYQARIALIDFYRGRSM
What is the function of this protein?
NAD(+) hydrolase (NADase) that generates 3'cADPR, a cyclization variant of cyclic ADP-D-ribose (also called v2-cADPR).  Also cleaves NADP(+), but does not cyclize the product.
What are the official names of this protein?
3' cyclic ADP-D-ribose synthase AaTIR, 3'cADPR synthase AaTIR, NAD(+) hydrolase AaTIR, AaTir.
Protein: TTCA_NEIG1
Sequence: MSKKTKQELENNKLSKRLRHAVGDTINDFNMIEPGDKIMVCLSGGKDSYALLDILRRLQASAPIDFELVAVNLDQKQPGFPEEVLPTYLESIGVPYKIVEEDTYSTVKRVLDEGKTTCSLCSRLRRGILYRTAKELGCTKIALGHHRDDILATMFLNMFYGGKLKAMPPKLVSDNGEHIVIRPLAYVKEKDLIKYAELKQFPIIPCNLCGSQPNLQRQVIGDMLRDWDKRFPGRIESMFSALQNVVPSHLADTELFDFAGLERGQNLKHGGDLAFDSEKMPERFSDGSEEDESEIKIEPQKAERKVINILANKPKTCGP
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED21_COCIM
Sequence: MADILTQLQTCLDQLATQFYATVAYLTTYHDHSPAIPPPSVPSAVPQLKKIPKNPPPAAPTSGTATNTPGAAGGPSGDTKDAAAGPSNAPQMQQQHQEQPPDAPPRPDSPNTFLMRQRELARDLIIKEQQIEYLISVLPGIKSSEAEQQERIKQLAEELRVVEEERSARRRELRRLGEKVDGLLGAVSRGTGISNSG
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYA_XANCB
Sequence: MNAPAKFSTSQIRSDFLAFFEGKGHTIVPSAPLVPGNDPTLLFTNSGMVQFKDVFLGAEKRSYVRAADVQRCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGDYFKKDAIAWAWELLTQVWKLPADRLLVTVYHTDEEAFELWRDMIGIPESRIVRIGDNKGAPYASDNFWQMADTGPCGPCTEIFFDHGDHIAGGPPGSPDEDGDRFIEIWNLVFMQFDRQPDGTLVPLPAPCVDTGMGLERLAAILQHVHTNYEIDVFQALIGKASALTGIADLENKSLRVIADHIRACSFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQLFFSKMVPTLVELMGEAYPELVVAQETVARALLAEEERFAETLDAGMKIFDDVASRSQEIIPGADAFRLYDTYGFPVDLTADIARERGMRVDMEGFEFAMERQRETARAAGKFGGGVALPADLVATMAPTVFLGYEAQDADALKVVALLKQGRPVDRAEAGDEVIVFTDRTPFYAESGGQVGDSGQLSGTDISIEVADTQKFAGQFHGHVGRIAEGTLKLGDVLSGGIDVQRRGKTILNHSATHLLHAALREVLGTHVQQKGSLVAPDRLRFDFSHFQPITAEELAVIERKVNAEVRTNHSVEVHNMAMQEALDFGAMALFGEKYGERVRVLKMGGYSTELCGGTHVSRTGDIGLFKITSEGGVSSGVRRIEAVTGQGALDYVAEEERRLGEAASLFGGNSTEIVDKVRALTDRQKRLERELESLKAKLASGATADLGASAVDVAGVKVIAVRLEGFDAKALREAMDRLKQQLGDSVIVLAGAAGGKVALVAGVNGSPTGKVKAGELLGHIASQIGGKGGGRPDLAQGGGEDGPALATALQGVPSWVKQHLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_VIBVU
Sequence: MTSITHAELGWNEVGTPVSDQFDDVYFSNVNGLEETRYVFLKQNLIPERWQEFDRRRFVIGETGFGTGLNFLAVWQAFNDFRRANPDATLKELHFVSFEKFPLSKQDLIKAHQAWPELAELAEKLHRHYPPAVPECHRIVLDNGAVTLDLWLGDIKDCLPSVPYGEEGIIDTWFLDGFAPSKNPEMWNQDLFNGMAKLARSECRVATFTSAGFVRRGLIEAGFAMKKVKGFGTKREMIAGCMETRQQQSRHAPYFNRTSASHLDSIAIIGGGIASAALAKALVQRGQKVTLYCKHAQAAEGASGNRQGAVYPLLNGNHDGVSRVFAPAFLFARQFVEQAAQALTFDHDWCGVTQLMWDEKSTNKLDKMLSGNFAPELIQKLSVGETAAKIGLPIDMASVHYPLGGWLCPAELTQALFTQLGTLDNFTAKFEQSVEQLIWDERSQQWQVHTQGQHDTYSAVVIANGHEFQTFSQTADIPLGQVKGQVSHVPATETLSKLKSVLCYDGYMTPVNPNNQHLCIGASYDRRHLDTEFDVNAQQENAERLTQCVPNQAWAKEVDTSGNLSRQGIRCVSRDHLPFVGNVGDFSAIKRQYADLPHTQAEEIEVISQFPNLFCLLGLGSRGLSSAPLMAELLASQICNDPLPLPVDVLEELHPSRMWVRKLRKGKAITEL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_SALG2
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYARAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_CLOP1
Sequence: MVKVESFELDHTKVKAPYVRKAGIKIGPKGDIVSKFDLRFVQPNKELLSDKGMHTLEHFLAGFMREKLDDVIDISPMGCKTGFYLTSFGDINVKDIIEALEYSLSKVLEQEEIPAANELQCGSAKLHSLELAKSHAKQVLENGISDKFYVE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RSMA_JANMA
Sequence: MKHIPRKRFGQNFLTDDTVLYNIIRAIDPQPQDTMVEIGPGLAAMTRLLLEGVQQMHVVELDRDLVERLKKSFDPKRLIIHSADALQFDFSTIPVPAGSKLRVVGNLPYNISSPLLFHLAEMAPHVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYHMELMFVVPPTAFDPPPRVESAIVRMIPLAQPLPCDQAKLEQVVLKAFSQRRKVIRNCLAGMFAESDLLEVGIDPQLRPETIPLAQYVALANRL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1D_SHEEP
Sequence: MATNFLVHEKIWFDKFKYDDAERKFYEQMNGPVAGSSRQENGASVILRDIARARENIQKSLAGSAGPGASSGPSGDHSELVTRIASLEVENQSLRGVVQDLQQAVSKLEARLSALEKSSPAHRATTPQTQHVSPMRQVEPPSRKAATATEDDEDDDIDLFGSDEEEDKEAARLREERLRQYAEKKAKKPALVAKSSILLDVKPWDDETDMAQLEACVRSVQLDGLVWGSSKLVPVGYGIRKLQIQCVVECRWGRPLERSHQVEEHVQSVDIAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-delta, EF-1-delta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: MUTS_SHEFN
Sequence: MTVIDTSDLEKHTPMMRQYLGLKAAHPDMLLFYRMGDFYELFYDDAKRASEMLGISLTARGKSGGDPIPMAGIPYHAVEGYLAKLVNIGQSVAICEQIGDPATSKGPVERQVVRIVTPGTLTDEALLQEKQDNLLAALYQGKTGFGYATLDISSGRFVVAELPTREALEAELQRTNPAELLYSEDFTDMLLINNMKGIRRRPEWEFDYDTCINLLLNQFGTKDLHGFGITDARLALQAAGCLMQYVKDTQKMALPHINSIVRFNQSESIILDAATRRNLELTQNLSGGRENTLAWVLDNTATPMGSRMLQRWIHEPLRNRQTIQYRHSAVSELIEQDLYQTLHEQLKSLGDIERIMARLALRSARPRDFSRLKQALTLLPEIQQTLAICQQPRLNTLVQLLGEFPEQHDLLERAIVDNPPMLIRDGGVIRTGYNNELDEWRKLSEGASDYLVELEAREKQQTGINTLKVGYNRVHGYYIEVSRLQSDRVPLSYQRRQTLKGTERYITPELKEYEEKVLSSQGKALALEKQLWEQLFDLLLPKLQELQQFATAAAELDILSNFAERAELFNYQCPQMSHDIGINIEAGRHPVVERVSQAAFIANPVALTPQRQMLIVTGPNMGGKSTYMRQVALITLMAHIGCFVPADHAQIGEIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATANSLVLMDEIGRGTSTYDGLALAWSAAEYLAKNVSALTLFATHYFELTQLPELLPSVINVHLDAIEHDDTIAFMHSVQEGAASKSYGLQVAALAGVPASVIKAAKHKLHQLENRDMTLSQQNPTQVSMNLLPPIPEPSLALEKLAQINPDELTPKQALDYLYELKRLSHTNT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PUP_MYCTA
Sequence: MAQEQTKRGGGGGDDDDIAGSTAAGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: AROB_COXBU
Sequence: MKTERVNVNVNNQPYPIYIGENLLQDKSLLQRHVKGRQVMIVSNETIAAFYLDPLKAIYQDFQCDTFILPDGEQYKTLEYWEHILHKLASCNHHRDTTLIALGGGVVGDITGFAAACYQRGVDFIQVPTTLLAQVDASIGGKTAVNHPVGKNLIGAFHQPKAVIIDLNTLNTLPEREFKAGMAEIVKAALIKDEKFFTDLENKMSDLLQRNFIFLQAVIKRAAEIKRDIVNADEKERSGERALLNLGHTFAHAIERLLGYGQWLHGEAVSAGLVLAAQLSHRKNLLDFESLQRICRLLTQISLPIHFPKSINADELLSAMYMDKKVANERLHLILLEDLGHAVVSDQVDDRELKSFLENG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_HAEI8
Sequence: MAKLTKKMKAIKAGVDSTKAYEINEAIAVLKQFATAKFVESVDVAVNLGIDPRKSDQNVRGATVLPHGTGREVRVAVFTQGANADAAKEAGADLVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKSGQIRYRNDKNGIIHTTIGKANFSEVQLKENLQALLAALNKAKPTTAKGIFIKKVSISTTMGAGVAVDQASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SELU_ECOLC
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.