PharMolix/UniProtQA huggingface dataset:
Protein: RL3_SYNS9
Sequence: MSIGILGKKLGMSQLFDEQGRAVPVTLIEAGPCRITQLKNDDTDGYAAVQIGFGETREKLINKPSKGHLTKSGEDLLRHLREYRVDNVDGLELGGSITVSDFEAGQKVDVSGDTMGRGFAGLQKRHGFSRGPMTHGSKNHRQPGSIGAGTTPGRIYPGKRMSGRYGGKKTTTRGLTILRIDSDRNLLVVKGSVPGKPGALLNIKPAVRVGAKPAKGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MFTR_MYCTO
Sequence: MPHESRVGRRRSTTPHHISDVAIELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQLQGLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQTPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQTVAWTMLGVALSAYEHWLRDESVSLTEALGAAFDVVGAGLDRLNQ
What is the function of this protein?
May regulate a gene cluster involved in mycofactocin expression.  Mycofactocin is a conserved polypeptide that might serve as an electron carrier (By similarity).
What are the official names of this protein?
Putative mycofactocin biosynthesis transcriptional regulator MftR.
Protein: SPH5_ARATH
Sequence: MEKVSIVCFFFFLLFGSGYGGLPPFWRATVVTMTNLIGGPPLTIHCKSKQDDLGIHVVPFKQEYHFKFQPNLWKSTLFFCSFQWDSQFKSFDIYDAQRDQGICDDCQWEIKPDGPCRLGKKAKCFPWK
What are the official names of this protein?
S-protein homolog 5.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SODM_CAPAN
Sequence: MALRNLMTKKPFAGILTFRQQLRCVQTFSLPDLSYDYGALEPAISGEIMQLHHQKHHQTYITNYNNALQQLHDAINKGDSPTVAKLQGAIKFNGGGHINHSVFWKNLAPTREGGGEPPKGSLGSAIDTNFGSLEAVIQKMNAEGAALQGSGWVWLGLDKELKRLVIETTANQDPLVIKGPNLVPLLGIDVWEHAYYLQYKNVKPDYLKNIWKVINWKYAAEVYEKECP
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LPTD_YERPN
Sequence: MKKRFPTLLATLIWTALYSQHTLADLAEQCMLGVPTYDQPLVTGDPNQLPVRINADKTEANYPDNALFTGNVIVQQGNSTLTANQVELTQVQKPGEVIPLRTVTATGDVNYDDPQIKLKGPKGWSNLNTKDTDMDKGKYQMVGRQGRGDADLMKLRDQSRYTILKNGTFTSCLPGDNSWSVVGSEVIHDREEQVVEVWNARFKIGKVPVFYSPYMQLPVGDKRRSGFLIPNAKFTSNNGFEFLLPYYWNIAPNFDATITPHYMERRGLQWQNEFRYLLAPGSGTMALDWLPNDRIYTGPDGTDKNATRWLYYWGHSGVMDQVWRFNINYTRVSDPAYFTDLTSQYGSTTDGYATQIFTAGYANENWNATLSSKQFQVFTAAGNSNAYRAQPQLDMNYYKNDVGPFDMHVYGQAAKFTSVNPTNPEASRFHIEPTVNLPLSNSWGSINTEAKLLATHYQQDIPASFADNASNPKLKDSVNRVLPQFKVDGKVVFDRSMDWATGFTQTLEPRAQYLYVPYRNQDDIYIYDTTLMQSDYSGLFRDRTYSGLDRIASANQVSTGLTSRIYDDARVERFNVSVGQIYYFSRSRTGNTEAIDNSNATGSLVWAGDTFWRINDQLGLKGGAQYDTRLGSLTLGNAIMEYRKDADRMIQLNYRYASPKYIQAAVPKVYNPDYQQGISQVGTTASWPIADRWAIVGAYYYDTKAKQPASQLVGLQYNTCCWAVNLGYERKITGWNAQGQTSKYDNKIGFNIELRGLSGGHSLGTAQMLNSGILPYQSAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PNP_STAAM
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAEVGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITEIDKQGRVNASHRALEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_LACAC
Sequence: MTIKEIKELLKGDVSEEEIANLEKDSRSGVQKLLISYRKKQKKLFEKKQAFLERFLYEKQFWQKGQLVAGVDEVGRGPLAGPVVTAAVIIDQDFDLLDVNDSKKLSPEKRLKLYPKILEEAVSVAVGVKNAQVIDQINIYEADRQAMAQAVNALDIKPDALLVDAMNVPVDLPQIELIKGDAKSNSIAAASIVAKVFRDKLMDDYDKIYPHYGFSRNAGYGTKEHIDALKQYGPTHIHRKTFAPVSDFFK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AV2_CLVN
Sequence: MWDPLVNEFPDSVHGLRCMLAIKYLQALEDTYEPSTLGHDLVRDLISVIRARNYVEATRRYHHFHSRLEGSSKAELRQPIQEPCYCPHCPRHKSKTGLDEQAHVQKAHDVQDV
What is the function of this protein?
Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Uncharacterized 13.1 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AV2/V2 family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity).
Protein: DNAJ_AZOVD
Sequence: MAKRDYYEVLGVERGAGEAELKKAYRRLAMKYHPDRNPDDKSAEEKFKEVNEAYEVLSDAGKRMAYDQYGHAGVDQSMGGGAGFGAGGANFSDIFGDVFSDFFGAGRAGARGGPQRGSDLRYTLELNLEEAVRGTTVTIRVPTLVHCKTCDGSGAKKGTTPVTCTTCGGIGQVRMQQGFFSVQQTCPRCHGSGKMIADPCPDCHGQGRVEEHKTLSVKVPAGVDSGDRIRLAGEGEAGTLGGPPGDLYVVVSVREHPIFQRDGKHLYCEVPISFADAALGGELEVPTLDGRVKLKIPEGTQTGKLFRLRGKGVAPVRGGAAGDLMCRVVVETPVNLSKRQRELLEEFRGSLQGNSSHSPKASGWFEGMKRFFDDL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_PSEFS
Sequence: MSQVNMRDMLKAGVHFGHQTRYWNPKMGKYIFGARNKIHIINLEKTLPMFNEALTFVERLAQGKNKILFVGTKRSAGKIVAEEAARCGSPYVDHRWLGGMLTNFKTIRASIKRLRDLEVQAEDGTFAKLTKKEALMRSRDLEKLDRSLGGIKDMGGLPDALFVIDVDHERIAITEANKLGIPVIGVVDTNSSPEGVDYIIPGNDDAIRAIQLYMGSMADAVIRGRNHVAGGTEQFVEEAPVAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SHKL4_NEMVE
Sequence: MDTRVIAVLFVAIMVLSSTNALPKQKGSYKNMNHADFLKGLDRASSKRDCRDSHWSCFFQSNYEDICSTAQAEECALSCGLCE
What is the function of this protein?
Probable neuropeptide.
What are the official names of this protein?
Protein ShK-like4.
Protein: ATPB2_LISIN
Sequence: MSKGQVIQVMGPVVDVKFEGGNLPEIYNALVIEYKSDAEEAPTSQLTLEVAIQLGDDVVRTIAMASTDGVQRGMEVIDTGSPITVPVGTVTLGRVFNVLGNTIDLDEPLPSDIKRNKIHREAPTFDQLATTTEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYFEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLTEQGIYPAVDPLASTSRALSPDIVGEEHYEVATEVQRLLQRYKELQDIIAILGMDELSDEDKQSVSRARRVQFFLSQNFHVAEQFTGQKGSYVPVKETVKGFKDLLAGKYDHIPEDAFRSVGRIEDVLEKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNFD_PSEA7
Sequence: MTLPRPTSPHIRGPLRTPAIMRLVLGACVPGLFTLTWLYGAGTLLNLAWAGLVALACEAAMLALRKRPPGMFLKDGSALVTALLLAVALPPCAPWLLTLVATGFALIFGKHLYGGLGQNPFNPAMLGYVVALVSFPLEMTRWPSPGSAPGLADSLHAFLGLAVQPDAWAHATALDVLKTDRSLTVDELFAADPAFGHLGGAGGEWVNLAFLLGGLFLLWRRLFTWHAPLGMLAGLFAMSLLFWNGSGSDSHGSPLFHLFSGATMLGAFFIVTDPVSGATSNRGRLLFGLGVGVLTYLIRAWGGYPDGVAFAVLLMNLAAPTIDYYTRPRTYGHRKAERGFRRGD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTD_ECOS5
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLDQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINTHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: TSN9_XENTR
Sequence: MARGCLCCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSFFIILLIILLAELILLILFFVYMDKVNENAKQDLKDGLLLYNTENNVGLKNAWNIIQAEMHCCGVTDYTDWYPVLGENTVPDRCCMENSQDCGHNSTSLVWKTGCYEKVKMWFDDNKHVLGTIGMCILIIQILGMAFSMTLFQQIHRTGKKYDA
What are the official names of this protein?
Tetraspanin-9, Tspan-9.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YL724_MIMIV
Sequence: MKICFEKNFECCNPCQPKCCPPPCPPKCCPPPCPPKCESICIDKCPNTCDPCCPPLVDDCLAKKLECLWRQCFCDARLIPEFGVPCQSDGVAVITHTLGRGLCNLKINGLKSQSILANNSFYSVEVSGCKWLNLYEIQLPDVPGKNGCKSSGEIYTEALVKLGISVEGDGYRWKGSQPYCLNIHSKAIGMHPIEFSKKQIAAIKAVLDYFFCDNKCCC
What are the official names of this protein?
Uncharacterized protein L724.
What are the subcellular locations of this protein?
Virion.
Protein: YFIB_SPICI
Sequence: MVNEEEKDLTAEGDSNNTGVSPDSIKNKTLDFYPKEKTTERKTRSRERISRKEVNLRFKAYLKSRLFRDYAYIIFAAFLGMASYDYFIAATTSNGITPSGIGGVARGIAVGIWPNQDQLQMQTSMYWVFYFVFNIPLFIFGVIKIGIRFSFRTIVYIGLQNGFHFAFAYIPVINPQELFFIVNYNSLNIFSNYGGMYQIWLFVFAAVAGILNGIAYGLVYKGGASTAGTDFVFAYYSAKKKISIANYNRIVNYIIIVVMLAIHTTLLSRSELTSIYFGKYWAANIEQIQRLGFKIDDGGLYDSDFTSHKIKYFFGPALFASYLFVVVQAITIDIIFPKFKYRSLMVITSKADAVVSGLQYVHYPNDIIRLPARD
What are the official names of this protein?
Uncharacterized protein in fibril gene 3'region, ORF2.
What is the protein family that this protein belongs to?
To M.genitalium MG432 and MG443.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BSD2_YEAST
Sequence: MPEQELLIGQEMNTLHAGSSTDGINVGNAGRTRDTQTGVEGETEIGSDEEDSIEDEGSSSGGNSTTERLVPHQLREQAARHIGKIGRHFNILDRLFKKRTQQSSDIQQGAMFDGVFSNLSAKPDTTETEGNNEQDIPPTYDEAAADMAPSYYGMDLNNSDIYYDEICIEGLPVGNIANLLWNIIVSTSFQFIGFLITYILHTSHAAKQGSRFGLGLTFIGYGYSMIPNDVTSKVGKNKSLNRMELEDPNEFDDVRLNSQSTTQDKFESHLNHGLDEEKQNIPWLAVFVAFLGLFITLKSIYDYIQVKKLEKKYLNQSQNQA
What is the function of this protein?
Required for homeostasis of heavy metal ions such as cadmium, cobalt and copper.  Controls metal ion transport and prevents metal hyperaccumulation by negatively regulating the SMF1 and SMF2 metal transport systems.  Under manganese-replete conditions facilitates trafficking of SMF1 and SMF2 metal transporters to the vacuole where they are degraded.
What are the official names of this protein?
Metal homeostatis protein BSD2, Bypass SOD defects protein 2.
What is the protein family that this protein belongs to?
Belongs to the BSD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Vacuole. Membrane; Multi- pass membrane protein.
Protein: PGK_PECCP
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEIALKQGARVMVTSHLGRPTEGEYNEEFSLLPVVDYLKEKLSSPVRLAKDYLDGVDVAEGELVVLENVRFNKGEKKDDEVLSKKYAALCDVFVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSGELEALGKALSEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFVAAQGHNVGKSLYEADLIPEAKKLLETCDIPVPSDVRVASEFSETATATLKSVTAIKDEEQILDLGDVSAERLAEILKNAKTILWNGPVGVFEFPNFRKGTETIARAIAESDAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALAM_DICDI
Sequence: MFKRSLKVLLSNPPINRVKPSSTIIQPLSNTTTTTIINNNNITNFEKMTHKKSMTIDNICQNVRNAQYAVRGELVIRAEAISHQLQKQKTEGTKTLPFEEIVYCNIGNPQQLKQKPLTYFRQVVSLVECPDLLDNPYVEKIYPADVISRAKEILGSINNTTGAYSNSQGIGLVLRSVADFIERRDGHKSDPSEIFLTDGASVGVQRILKLLIKDRSDGILIPIPQYPLYSATIELYNGSQLGYLLNEEKGWSLEISQLEHSYNDAVSKGINPRALVIINPGNPTGQCLDRANMEEIVKFCLEKNVVLLADEVYQENVYVKESKPFISFKKVVKDMGGDYADLEMVSFHSVSKGFVGECGKRGGYMELNGVTQDVKAEIYKLASIGLCPNVIGQLVVDLMVRPPVAGEQSHDLYLKERDNIYESLKKRANLLTNALNNLEGVTCNPSEGAMYAFPQIRLPAKAVEYANSIGKAPDAYYCIQLLEATGICVVPGSGFGQKDGTWHFRTTFLPSEEAIEGVCKRIADFHQSFMNKYK
What are the official names of this protein?
Probable alanine aminotransferase, mitochondrial, ALT, Glutamate pyruvate transaminase, GPT, Glutamic--alanine transaminase, Glutamic--pyruvic transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DHAA_MYCTU
Sequence: MTAFGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDALDLGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGRIRDYVRSWPNQTEITVPGVHFVQEDSPEEIGAAIAQFVRRLRSAAGV
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase 3.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: FOLD1_ACIAD
Sequence: MSLALLQQHSPKIIDGKAIAQSVLEEVKLEVERYKAQGIEPCLAVVLVGEDPASQVYVRNKVQKAAFVGIRSLEFRFDADLSEDELLTQIDRLNTERGVHGILVQLPLPKQINETRVLERIHPQKDVDGFHSENVGGLSQGRDVLTPCTPTGCIRLLKDSLGDDLSGLHAVVIGRSNIVGKPMAALLLKESCTVTVVHSKTRNIEQVCQQADIVVAAVGKANMINASYLKADAVVIDVGINRIMTHEKTRLVGDVDFEDALPMVSAITPVPGGVGPMTIAYLMKNTLQAVRLQHPQI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ATP5S_MOUSE
Sequence: MMMFGKISRQLCSLKKIPWSCDSRYFWEWLNTVFNKVDYERLRDVGPDRAASEWLLRCGAKVRYCGHQKWLHDYNTLPGSSIDRYKIQAIDATDSCIMDIGLDHMVGLEHVEKITLCKCHYIEDNCLQRLSQLENLRKSLLELEIIACGNVTDNGVIALRHFRNLKYLFLSDLPGVKDKEYLAQVFKTALPSLELKLNLK
What is the function of this protein?
Involved in regulation of mitochondrial membrane ATP synthase.  Necessary for H(+) conduction of ATP synthase.  Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
What are the official names of this protein?
ATP synthase subunit s, mitochondrial, ATP synthase-coupling factor B, Distal membrane arm assembly complex 2-like protein, Mitochondrial ATP synthase regulatory component factor B.
What is the protein family that this protein belongs to?
Belongs to the ATP synthase subunit s family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: PYRE_BACMK
Sequence: MKKEIASHLLEIGAVFLQPNDPFTWSSGIKSPIYCDNRLTLSYPKVRQAIAAGLEELIKEHFSTVEVIAGTATAGIAHAAWVSDRMDLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELESGKEKLEAANVASYSLSDYSALTEVAAEKGMIGQAETKKLQEWRKNPANEAWITA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: SSRP_LIMRJ
Sequence: MAKKSHQENNDNLIAQNKKARHDYFVTDTVEAGLVLTGTEIKSVRAHRVNLKDGFAQVRNGEAWLMNVHISEYDNGTYFNQDPLRNRKLLLHKKEINKLVGALQDKGVTLIPLKMYIKHGYAKVLLGLAKGKHQYDKREAIKRREQNREIERVMKHY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MTND_BACVZ
Sequence: MATIRIHDEKNTLIEHQEEVARFLDEQEVIYEQWNIEKLPSELSEKYDLTEDEKERILAVFDTEIQDISARRGYQSQDVISLSDTTPNLDELLKNFQREHHHTDDEVRFIVSGHGIFVIQGKDGTFFDVRLNPGDLISVPENIRHYFTLQEDRRVVAIRIFVTTEGWVPIYENESVQN
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: Y4OQ_SINFN
Sequence: MTISQTVPRGAVAVRRRRRIRISTVVWFTMPAAAIMLLVLGVPLVYSFYYSLTGWSLVVPGSDQDFIGLLNYTDVLRSSEFWAAIRVTLIYAVVAVSLECALGILFAVLLNLEFFGRGLFRSLMLIPMVITPAVVGIFWKLLYEQDSGVFNYLLGTLGFEPVPWLSLTVALASVIIVDVWQSTPFFTLIILAGLQSLDRDTVSAAQADGANALQVFRYLTLPHLVPYIMIAAAFRIIGVMADFDKIFLLTLGGPGNVTTTLSVYAYNTGFKVFDIGRTTAISWIYVVFVLAISAPLIWRLFRGASVNRH
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4oPQRS.  This system probably transports a sugar-like molecule.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein y4oQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_SALEP
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MNMA_MYCTU
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHEVVGVHMALSTAPGTLRTGSRGCCSKEDAADARRVADVLGIPFYVWDFAEKFKEDVINDFVSSYARGETPNPCVRCNQQIKFAALSARAVALGFDTVATGHYARLSGGRLRRAVDRDKDQSYVLAVLTAQQLRHAAFPIGDTPKRQIRAEAARRGLAVANKPDSHDICFIPSGNTKAFLGERIGVRRGVVVDADGVVLASHDGVHGFTIGQRRGLGIAGPGPNGRPRYVTAIDADTATVHVGDVTDLDVQTLTGRAPVFTAGAAPSGPVDCVVQVRAHGETVSAVAELIGDALFVQLHAPLRGVARGQTLVLYRPDPAGDEVLGSATIAGASGLSTGGNPGA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFA_PHANO
Sequence: MPSIHPLIDNGITKGDEHFKGGKLYCHCPSNKVEVTLSSNVAHNHACGCSKCWKPKGALFSVVGVVPVDALSVTANGNKLHVVDSSAAIQRNACKDCGVHLFGRIVNDHPFKGLDFVHVELSDSKGWQEPQFAAFVSSIIEQGFPPNQIDAVREKFRKEGLQTYDVLSPTLMDLIATYTGQKSGKLSSKL
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Putative glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CSOSB_HYDCU
Sequence: MSTEYGIALGMIETRGLVPAIEAADAMTKAAEVRLVSREFVGGGYVTVLVRGETGAVNAAVRAGADACERVGDGLVAAHIIARPHKEVEPVLTMEKK
What is the function of this protein?
One of shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, ccbL-ccbS) is sequestered.  Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome.  The shell probably limits the diffusion of CO(2) into and out of the carboxysome.
What are the official names of this protein?
Carboxysome shell protein CsoS1B.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.