PharMolix/UniProtQA huggingface dataset:
Protein: UBC5_ARATH
Sequence: MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFFVEFSGPKDSIYEGGVWKIRVELPDAYPYKSPSVGFITKIYHPNVDEMSGSVCLDVINQTWSPMFDLVNVFETFLPQLLLYPNPSDPLNGEAAALMMRDRPTYEQRVKEYCEKYAKPRADTEEMSSDDEMSEDEYASDGDDEDDVAIAGKLDP
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 5, E2 ubiquitin-conjugating enzyme 5, Ubiquitin carrier protein 5, Ubiquitin-conjugating enzyme E2-21 kDa 2, Ubiquitin-protein ligase 5.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: REEP5_BOVIN
Sequence: MSAAMRQRFDQFLHQKNCMTDLLAKTEAKTGVNRSFIALGVIGLLALYLVFGYGASLLCNLIGFGYPAYVSIKAIESPNKEDDTQWLTYWVVYGVFSIVEFFSDLFLSWFPFYYMLKCGFLLWCMAPSPANGADLLYKRIIRPFFLKHESQVDNVVNDLKDKAKETADTISKEARKAAVSLLGEEKKST
What is the function of this protein?
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
What are the official names of this protein?
Receptor expression-enhancing protein 5.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network. In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery.
Protein: RNH_EDWI9
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRQHEKALSAGYRLTTNNRMELMAAIVALETLTSACQVALFSDSQYVRQGITQWIHGWKRRDWKTADKKPVKNVDLWQRLDQAIGPHQVEWIWIKGHAGHPENERCDELARRAAGTPTQDDSGYTPG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_STAAC
Sequence: MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHNLNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UXUA_ECOHS
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RIF2_YEAST
Sequence: MEHVDSDFAPIRRSKKVVDSDKIVKAISDDLEQKNFTVLRKLNLVPIKKSVSSPKVCKPSPVKERVDHVFYQKFKSMALQELGTNYLSISYVPSLSKFLSKNLRSMKNCIVFFDKVEHIHQYAGIDRAVSETLSLVDINVVIIEMNDYLMKEGIQSSKSKECIESMGQASYSGQLDFEASEKPSNHTSDLMMMVMRKINNDESIDHIVYFKFEQLDKLSTSTIIEPSKLTEFINVLSVLEKSNNIAFKVLIYSNNVSISSLLSTSLKKKLNTKYTVFEMPILTCAQEQEYLKKMIKFTFDSGSKLLQSYNSLVTCQLNNKESNLAIFFEFLKVFPHPFTYLFNAYTEIIVQSRTFDELLDKIRNRLTIKNYPHSAYNFKKNQRLPLKLTRKVHDR
What is the function of this protein?
Involved in transcriptional silencing and telomere length regulation.  Its role in telomere length regulation results from either a block in elongation or promoting degradation of the telomere ends.  Loss of RIF1 function results in derepression of an HMR silencer, whose ARS consensus element has been deleted, and in the elongation of telomeres.  RAP1 may target the binding of RIF1 to silencers and telomeres.
What are the official names of this protein?
Protein RIF2, RAP1-interacting factor 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: CCD61_CHICK
Sequence: MEEPRCLQANCFFRGKEHSIQLSVSQAVLEVEVEERRSTKRWRGHFDAASVEDLTRKTGNFKQFGIFCSMLEAALMKSSEAVSLELLTYGDLEALRCCKVGVATRVPPSTSPLSSKRYLILVYCVEFDRIHYPLPLPYIGEADMAALRRLVQEQQDELAQLRDELRRAQQEVWRLEDERLRDKAWHQQEQRRMTKELTEVKAAEKMLRAHVKTLTAELAVCRKGRSTSATAPGCPQDRRRSNSRDSRSSSQGRLPPRSPSPAGSRPPRFNPTAFVRSREQRRQEAELRRQKLPRGTVSSGDNCRRRGRRSSSAESLQSRRSAQSSGSEADTCPQRRRGLGGPSTRSPLSASSCNSTSVASHPNRGCKQHGKENLGTEPSATLSEIDARLQALQAYISTLGTHM
What is the function of this protein?
Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker.  In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning.  During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure.  Plays a non-essential role in ciliogenesis.
What are the official names of this protein?
Centrosomal protein CCDC61, Coiled-coil domain-containing protein 61, VFL3 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC61 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Localization at the centriolar satellite is dependent on intact microtubule network. Localizes at the centriole subdistal appendages and proximal ends. Localized to centrosomal/satellite-like structures with the onset of centrosome separation in early G2.
Protein: NUOCD_SODGM
Sequence: MTELMTQNSALPVWQSQDHQDDPVIAELRNHFGPDAFSVQPTRTGIPVVWVKREQILKVLTFLKKLPKPYVMLYDLHGVDERLRTHRQGLPAADFTVFYHLISIDRNRDIMLKVALSENDLHLPTCTRIFPNANWYERETWEMFGMTFDGHTHLTRIMMPKSWEGHPLRKDYPARATEFDPFVLTKQKEDLEMEGLTFKPEEWGMKRGKDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRVEYLGGCVNEMPYVLAVEKLAGIVVPDRVNVIRVMLSELFRINSHLLYISTYIQDVGGMTPVFLAFTDRQKIYDVVEAITGFRMHPAWFRIGGVAHDLPRGWEGLLREFLDWLPKRLDSYVKVALRNSVLRARAEGVAAYGAKEALDWGVTGAALRATGIDFDVRKWRPYSGYENFNFEVPVGDGVSDCYSRVMLKVEEMRQSLRILEQCLNNMPAGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSFPHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ASTD_SHEB5
Sequence: MTHYIQGQWHAGKGHDVASINPANAQTIWTGKTATAEQVNAAVDAAREAQFDWFMLGFDARLAIVEAYRSQLEANKAELAETIAQETGKPQWETATEVGAMIGKIALSAAAYNKRTGTEANDTPAGRAVIRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVIFKPSELTPKVAELMVSLWDKAGLPAGVLNLVQGEVDTGKALASHPQLDGLFFTGSSRTGHFLHQQYAGHPGKILALEMGGNNPLIIKGVQDIKAAVHDILQSAYISSGQRCTCARRLYVEQGEQGDALIAMLAAAVKQIKVGPWNAQPQPFMGSMISETAAKGMVAAQTNLQNLGGVSLVELTHLEAGTGLVSPGLIDVTAIDVLPDEEYFGPLLQLVRYSDFDQAIKLANQTRYGLSAGLLADSREDYDYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADAVSLPATLSPGLSL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: ANMK_CUPPJ
Sequence: MRAQGDRYIGIMSGTSMDGADAVLVDFSGERPAVLAAAHEPFPDALRADFGQLQQPGDNEIHREALAANALARVYAGCVTTLLGQAGLQAGDVAAIGAHGQTIRHRPGLYDEIGYTRQSQHPALLAELAGIDVVADFRSRDVAAGGQGAPLVPALHQALFGDGAEARVVCNIGGISNISVLPGDSGAVIGFDCGPGNALLDYWIGEQLGMPYDDDGAWAASGRVDEALLAACLADPYFNAAPPKSTGRDLFHPAWLEARLATRSGPALSPADVQATLAALTAEAIARDVRAHAAPAKRLIVCGGGARNGYIMRRLAQALPGVAVQTTEDFGVPVSQVEAIAFAWLARQCLLRLPGNVATVTGAAGPRVLGAIYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: THIM_CLOD6
Sequence: MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSYEEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAELTSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVVATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLTMSLSGELANLNNPPIGTFKENLMNAIYQMDIDALSKNSNIEFLN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: BDNF_PROLO
Sequence: MTILFLTMVISYFGCMKAAPMKEANVRGQGSLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Important signaling molecule that activates signaling cascades downstream of NTRK2.  Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2.  Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).  Binding to NGFR and SORCS2 promotes neuronal apoptosis.  Promotes neuronal growth cone collapse.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [BDNF precursor form]: Secreted. Note=A proportion of BDNF is secreted as immature precursor (proBDNF).
Protein: TPPC1_BOVIN
Sequence: MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQTVQSELFRSRLDSYVRSLPFFSARAG
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: ACSA_BARQU
Sequence: MSEKIYPVPTDIKKNALINEETYQKWYRESINDPEAFWAKHGQRIEWFKPYTKVKNTSFNGDVSIQWYEDGITNVAYNCIDRHLKNSGNHIALIWEGNNPYHDKKITYNELYEHVCRFANILKNHGVKKGDRVTIYLPMIPEAAYAMLACARIGAIHSVIFAGFSSEAIADRIVDCKSTFIITADQGLRGGKLIKLKNNIDHAIDIAARRGVHVNQVLVIRRTSGTIDWVKGRDFWYHEEISHAKTDCPAEMMNAEDPLFILYTSGSTGKPKGVLHTTAGYLVYVSMTHQYVFDYHPGEIYWCTADIGWISGHSYLIYGPLCNGATTLMFEGIPTFPDQGRFWEIVDKHKVNTLYTAPTAIRALMGAGNSFVEHSKRTSLRLLGTVGEPINPEAWKWFYHTVGDNRCPILDTWWQTETGGHMITPLPGATQLKAGSATHPFFGVQLQIIDGEGNVLEGEAEGNLCIIDSWPGQMRTLYNDHERFIETYFSTYKGKYFTGDGCKRDNDGYYWITGRIDDILNVSGHRLGTAEIESALVSHPAISEAAVVGYPHPIKGQGIYSFVTLMEGITPSEELYKDLIQHVKKEIGSIALLDKIQFTPQLPKTRSGKIMRRILRKIAENDFDNLGDISTLAEPQVVDDLIANRQNTEATA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RPOY_ENTFA
Sequence: MIYKVYYQETKIRNPKREDTKSLYMEADSDVIVRQLVEENTPYNIEYVQLLDEKHLAYEQEHADFTLTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RL14_LACLS
Sequence: MIQTESRLKVADNSGAKELLTIRVLGGSSRKFAGIGDIVVATVKSAAPGGAVKKGEVVKAVIVRTKSGAKRPDGSYIKFDENAAVLIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLI3_CHICK
Sequence: MEAQSHSSTTTEKKKVENSIVKCSNRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQGGQGLSKISEEPSTSSEERASLIKKEIHGSISHLPEPSVPYRGTLVTMDPRNGYMDPHYHPPHLFQAFHPPVPIDARHHEGRYHYEPSPIPPLHVPSALSSSPTYSDLPFIRISPHRNPAAASESPFSTPHPYINPYMDYIRSLHSSPSLSMISAARGLSPTDAPHAGVSPAEYYHQMALLAGQRSPYADIIPSAATAGAGALHMEYLHAMDSTRFPSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSCSSWSASGSYGHLSASAISPALSFTYPPTPVSLQQMHQQIISRQQTLGSAFGHSPPLIHPAPTFPTQRPIPGIPSVLNPVQVSSGPSESTQHNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGAGSVQEQPEGMTPVKEEGDKDESKQEPEVVYETNCHWEGCSREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDPGSHSQTRSPGQQTQGATGEQKDLNSTTSRREECLQVKAVKSEKPMTSQPSPGGQSTCSSEQSPISNYSNNGIELTLTGGGSVGDLSVIDETPIMDSTISTATTALGLQARRNMTGTKWMEQVKLERLKQVNGMLPRLNPVPPSKAPTLPPLIGNGTQSNSSCSVGGSMTILPNRNELSSTDITVLNMLNRRDSNTSTISSAYLSSRRSSGISPCFSSRRSSDASQAEGRPQNVSVADSYDPISTDASRRSSEASQCDDLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRMALLGDCRESGISPLPPVNAPRRCSDGGANGYSRRHLLSHDALGNGTRRASDPVRMVSNNLSVPRVQHFNSLNSFNSPALPPSMEKRNLVLQNCTHSEGGVFRGFSSPCPPSISENVTLEAVTMEAGGSLNDEDLLPDDVVQYLNSQNQGTCDHLLNNVLDSNKMHHSVVLGNNNPSSFDRAPPASSQPAGSEVSKSDLPIQWNEVSSGSSDLSPTKLKCSQRSAVQQARAFGLYNNMMVQQQNLQRGNVYQQNGYQNLMENNGSYSLQQNTVLGSGASSSFGMQPNKPYGESVSRQPMIFGAMDSSCGITVQGQKLRSSNMPVSGNQQNFGHPIASSDQATSMANGMQNRNVMEQEYLQNELVGDGIHYQGVNQSSPMTLGQVSPTSQSSLHQGPQSCPPVSHTIGNQSSGLSVAKSYQPCANYSGNRRQNVLRNNLAQQQGHVSDGNQTYRVNTIKLEMQGQSQQFCSNMQNYSGQLYDQTTGFSHQAMKIGSSFFVSEANCLLQETATANSSELLSPGANQVSSTVDSLDSNSLEGVQIDFDAIIDDGDHVSLISGALSPSIIQNLSRNSSRLTTPRASLTFP
What is the function of this protein?
Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development.  The full-length GLI3 form (GLI3FL) acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor.
What are the official names of this protein?
Transcriptional activator GLI3, GLI3 full-length protein, GLI3FL.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KAD_CUTAK
Sequence: MRLLIMGAPGAGKGTQATAIAEHYSVPAISTGDMFRTNIKNGTELGKKVKAIMDAGDLVPDELTDAIVVDRLNQDDAANGFLLDGYPRNMHQVEALDAYLKEHGQRLDAVISLDVDPELLTQRLLKRAEIEGRTDDNEETIRNRMKVYSSQTEPLLEHYRSAGILVPVDGVGEIDEVRQRIFAALDSKN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_CLAMS
Sequence: MIDPQTLRDHPDLVIASQELRGASVEVVDQAVAADSERRQAITEFEGLRAEQNAHGKLVAKADKADKPRLIAEVQELKARVTAAQERAQQAEAALDEAMRRIPNIVIDGVPAGGEDDWALLREVGEKAAFDFEPRDHLEIGEILDAIDMGRGAKVSGARFHFLKGIGARLEIALMNFGLARALEAGLVPLITPTLVKPEIMAGTGFLGAHADEVYHLDDDDLYLTGTSEVALAGYHADEILDLAAGPIRYAGWSTCYRKEAGSYGKDTRGIIRVHQFQKLEMFSYVDPADAEAEHERLLAMQERMMQDLGLAYRVIDTAAGDLGSSAARKYDVEAWIPTQGAYRELTSTSNCTTFQARRLGTRFRGEDGRTSPVATLNGTLATTRWIVAILETHQRADGSVRVPEALRPYLGGLEVLEPATAKAAR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYT9_ORYSJ
Sequence: MRTSSLVLFAAVAVFGAACTAAAGDESWKTIDANDRHVQDVALWAVAETDWASATGGLTLNTVDGAEKRFEAGVNYYRLTLEASSRVVAKYLRFQAVVYEEGDEHKLVSFVPIH
What is the function of this protein?
Specific inhibitor of cysteine proteinases.  Probably involved in the regulation of endogenous processes and in defense against pests and pathogens (By similarity).
What are the official names of this protein?
Putative cysteine proteinase inhibitor 9, Oryzacystatin IX, OC-IX, Oryzacystatin-9.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RAD2B_ARATH
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWLNEIDRYASENVNKLLVGNKNDLTSQKVVSTETAKAFADELGIPFLETSAKNATNVEEAFMAMTAAIKTRMASQPAGGAKPPTVQIRGQPVNQQSGCCSS
What is the function of this protein?
Protein transport.  Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) (By similarity).
What are the official names of this protein?
Ras-related protein RABD2b, AtRABD2b, Ras-related protein Rab1A, AtRab1A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane. Golgi apparatus membrane; Lipid-anchor.
Protein: COBH_MYCTU
Sequence: MLDYLRDAAEIYRRSFAVIRAEADLARFPADVARVVVRLIHTCGQVDVAEHVAYTDDVVARAGAALAAGAPVLCDSSMVAAGITTSRLPADNQIVSLVADPRATELAARRQTTRSAAGVELCAERLPGAVLAIGNAPTALFRLLELVDEGAPPPAAVLGGPVGFVGSAQAKEELIERPRGMSYLVVRGRRGGSAMAAAAVNAIASDRE
What is the function of this protein?
Catalyzes the conversion of precorrin-8X to hydrogenobyrinate.
What are the official names of this protein?
Precorrin-8X methylmutase, HBA synthase, Precorrin isomerase.
What is the protein family that this protein belongs to?
Belongs to the CobH/CbiC family.
Protein: XPT_STRPM
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BRASB
Sequence: MTLPGINKAVLIAGPTASGKSALALELAQKAGGAVINTDSMQVYRDLRVLTARPSLAEEAAVPHRLYGCVDAAVNYSAGHYVRDAKEVLDEVRRGGGLPIFIGGTGLYFKALTRGLSAVPPVPDEVREAVRLRLDRDGVEALHAELARRDAAAAARLNVRDRTRIARALEVIEATGRPLAEWHAETTPPLLPEGSYRALFIAPEREALYARIDARFDAMLADGALEEVARLAARGLDPLLPAMKAHGVPALIRHLRGEITREEAAMIGKADTRHYAKRQFTWFRHQLPEFDWLTPEQARGWVAFL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS11_LEIXX
Sequence: MAAPKSAARKPRKKEKKNIAVGQAHIKSTFNNTIVSITDTTGAVLSWASSGGVGFKGSRKSTPYAAQLAAESAARQAQEHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVGSINDVTPQAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PSBE_PROM3
Sequence: MAAGSTGERPFFEIVTSIRYWVIHAVTLPSIFLAGYLFVSTGLAYDTFGTPRPDAYFQASESKAPVVSQRYEAKSQLDLRLQ
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.