PharMolix/UniProtQA huggingface dataset:
Protein: NTPPA_BRUA2
Sequence: MNVQHKLVLASGSPRRIELLGQAGIEPDRIHPADIDETPQRAEHPRSLARRLSRDKARKAHEQLQGEAGFSGALVLAADTVVAVGRRILPKAEIEDEARECLRLLSGRTHKVFTGVCLVLPNGNLRQTLVETRLRFERLSRLQINAYLSSGEWRGKAGGYAIQGLAGSFVVKLVGSYTNVVGLPLQETVGLLADGGYPVYANWGTGKV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_METFK
Sequence: MSLNTHDVKRIAHLARIAVSEEEAEATLVKLSGILGLIEEMQAVDTSGIVPMSHSQDVTQRLREDVVTESNQRDLLQSIAPAVENGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MNMG_SPHAL
Sequence: MHSSATFDVIVVGGGHAGTEAAAAAARLGARVALVSFDPTLIGTMSCNPAIGGLGKGHLMREVDALDGWMARAADAAAIHYRMLNASKGAAVQGPRIQADRKLYRAAIQTLLAAEEGITVVAGEAAALRLSNGGRIAGLDLADGTALTARAVVLATGTFLGGRLFRGEERMEGGRIGEAGSHRLAGQLRAAHLPMARLKTGTPPRLDGRTIDWARLQEQPSDGGRWTCSTWNNARTVPQIFCAITRTNAESHRIIAENLHRSPLFTGAIGAAGPRYCPSIEDKIHRFADRDGHQVFLEPEGLDTHLVYPNGISTSLPADVQLAMLRTIEGLEAVEMVVPGYAVEYDHIDPRALDRTLQVRAMPGVWCAGQINGTTGYEEAAAQGLVAGANAALAVQGREPLILDRSESYIGVMVDDLVLQGVTEPYRMLTARAEYRLRLRADNAATRLTPKGIALGLVRPATAALFARRMAERARAGALLEAPVATADYGAIGLPLPGDGIARRRIDLLRFPGATVERLTILVPEIESIDRAILSEVVEDAHYAPYIARHEAELRALAANEAILLDPALDYAAIGGLSREMVERLSKARPETLGQAARIDGVTPAALTAIMVHSRRRAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y925_METJA
Sequence: MSIFYVLGKKGTIEILYKIKEGVNSFTSIKNALDMEGCGVSTRTLAERLNELEDENLIQKDGSKYYLTKKGQEALEIIENVMKWEAKWKEAKIPKIIIGMLGDKER
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MJ0925.
Protein: JAL9_ARATH
Sequence: MIFIYIFLFLSSAIIDSNGFAMAQKLEAKGGKGGKEWDDGAGHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGFTQMFEIDYQNGEHIVSVDGYFDKSGVMQALEFKTNRKTSEVIGYPKSNTKFSLGGVNGKMINGFHGSAGKALNSIGAYLTKVPPTKSELVGGWGGDYWDDGPNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSSHGNKEGETEEFAIDYPNEFLISVEGTYDSILFPDHYVLVITSLSFKTSKGRISPTYGVVSGTKFVLESQGNAIVGFYGRNGGAFDAIGVYFSPI
What are the official names of this protein?
Jacalin-related lectin 9.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: CLPS_COREF
Sequence: MCSSPSAPTAEPDVEMDVHTVSSENLPWLCIVWDDPVNLMSYVTYVFQTVLGYSRKRANELMMQVHTEGKAVVSSGEKDKVEGDVKKLHVAGLWATMQQAG
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ARGC_SACEN
Sequence: MTVRVAVAGASGYAGGELLRLLLSHPEVEIGALTAGGNAGSELGAHHPNLLPLADRVLADTTTAQLSGHDVVFLALPHGHSAAIAAELGDDTVVIDCGADHRLNDPTDWARWYGGEHPGTWPYGIPELPGLRERLTGARRVAVPGCFPTVSSLTIAPALAAGLVDPEVVVVAVTGTSGAGRALKPHLLSAEVMGSASVYGVGGAHRHTPELIQNLSAAGGEPVRVSFTPVLAPMARGILATCSAALRADTDAEAVRKVYLDAYGDEPFVHVLPEGTWPQTSATLGANTVHLQVTVDDDAGRLVAVGAVDNLTKGTAGAAVQCMNLALGLPETTGLPLVGVAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRB5_CAEEL
Sequence: MAEINQTKCDLAFQISYHPIYRLAQFWTLSVSLLAVPSLLYFLLKRVLLLPFHGNLKCLLITYFSSIFLYALVLCFDFSYQCLIPFIVTTKCSLIIDQTLYKCGHMTSLFFLTTPMLLPFGFSIERFVAVGMAYKYEKMRTLLGPILCFILVAPNFVVFYFLFRDEQFTDSFISFLVLPNTPAVQFNNYLWFLLYAKIGNFCCNCVLLIFHKRFKNTYLKKKTSLSVRYALEEISNSSKFTLILTFTHLVFFGAYTIGSILVRTLGESFFGNFLNFYVARGVNCAVPTYNLLIAFVGLISLRQLNSRRHAKILTKVLIRVTGQEGARNYDDIIMQQWNTVSNRTR
What is the function of this protein?
G-protein coupled receptor (Probable).  Plays a role in the navigational capacity of sperm and promotes the targeting of sperm derived from males to the fertilization site in the uterus of hermaphrodites (PubMed:28662030).
What are the official names of this protein?
Serpentine receptor class beta-5, Protein srb-5.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite.
Protein: FUS_SENDO
Sequence: MATYIQRVQCISALLSVVLTTLVSCQIPRDRLSNIGVIVDEGKSLKIAGSHESRYIVLSLVPGIDLENGCGTAQVIQYKSLLNRLLIPLRDALDLQEALITVTNDTMTGADVPQSRFFGAVIGTIALGVATSAQITAGIALAEAREAKRDIALIKESMTKTHKSIELLQNAVGEQILALKTLQDFVNDEIKPAISELGCETAALRLGIKLTQHYSELLTAFGSNFGTIGEKSLTLQALSSLYSANITEIMTTIRTGQSNIYDVIYTEQIKGTVIDVDLERYMVTLSVKIPILSEVPGVLIHKASSISYNIDGEEWYVTVPSHILSRASFLGGANIADCVESRLTYICPRDPAQLIPDSQQKCILGDTTRCPVTKVVDNIIPKFAFVNGGVVANCIASTCTCGTGRRPISQDRSKGVVFLTHDNCGLIGVNGIELYANRKGHDATWGVQNLTVGPAIAIRPVDISLNLAAATDFLQDSRAELEKARKILSEVGRWYNSGATLITIIVVMIVVLVVIIVIVIVLYRLRRSMLMSNPAGRISRDTYTLEPKIRHMYTNGGFDAMTEKR
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) interacts with HN tetramer at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0, Protein F.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: RS15_HAMD5
Sequence: MSLNAEQKAKVVLEHGSSAHDTGSTEVQVALLTLRINDLQKHFLEHKKDHHSRRGLLRMVSQRRKLLDYLKKRNISKYTDLIQSLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HEM1_SHIBS
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: EFPL_SALG2
Sequence: MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSAGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: ARLY_RALPJ
Sequence: MTSQLAKKAEAWSARFNEPVSDLVKRYTASVFFDKRLALFDIQGSLAHAAMLAKQGIIAEADRAAIEQGMAQIRQEIEAGTFEWKLDLEDVHLNIEARLTAMAGDAGKRLHTGRSRNDQVATDIRLWLRSEIDNIVGLLKALRGALLDLAEQHTNTIVPGFTHLQVAQPVVFGHHLLAYVEMFTRDTERMLDARRRVNRLPLGAAALAGTSYPIDREFVAQQLGFEGVCRNSLDAVSDRDFAIEFCAAAALIMTHVSRFSEELVLWMSPRVGFIDIADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLIGLLTLMKGQPLAYNKDNQEDKEPLFDTVDTVVDTLRIFADMVPGITVKADAMRAAALQGYATATDLADYLVKRGLPFRDAHEAVAHAVRACDDLRCDLADLSVAQLRDICGLGDKANLIGDDVHTVLTLEGSVASRNHIGGTAPEQVKQAIAFARAALAE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_BRUAB
Sequence: MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERILYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMIMKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKGRFKTVDAEGNPVLKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVYMMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMIEEKDVEIIEKAGIQSIRIRSALTCETRNGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRNVVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGLSVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIEKGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMTNQIRRIATARDELIIDERRKTSGSAEANAMLVDMTNNAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: G6PD_HELPJ
Sequence: MLDFDLVLFGATGDLAMRKLFVSLYEIYIHYGFKNDSRIIASGRKELSNEEFLALLCEKTQLHSREKGEEFLTHISYLRVRLDNPKDFEELSKIATNNKPLIFYFSISPSFFATTAQNLAQNALNHANTRLILEKPLGHDLKTCKEIFQSISAFFKEEQIFRIDHYLGKKGVQNILELRLNNPILNILWDQISAVEICVYETLGVEERGEFYDKIGALRDMVQNHLLQVLSLIATDLPNDLKDLRQEKIKVLKTLQPPKDFTKQVIRAQYQGYRDENKVHKESQTETFVAIKAFLDTPKFKGVPFYLKHAKKMPRNQASVKIHFNAVNTLEFFLSQDKITLTLKDHQNPLILETHNKQEFLQPYAKLLYDAIPNNHYNFAHQLELEASWVFIDTLIEGFINNATPLYSYESHNLNESEFLKPLYQ
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: GAL1_LIMRD
Sequence: MDKQQFLAEYQDVFKEPGKDVFFSPGRINVIGEHTDYNGGHVFPCAISIGTYGVYGPREDTTVAIYSANSAKEEDSKIITFDINDTEPQNAKDEKWVNYFKGMLVYLKQRGFKIDHGFNLYIHGFLPYGSGLSSSASIEMLMGNILKDEFNLDIDEIELVKLGQKTENDFVGLNSGIMDQFAVGMGKENNAIYLDCNTLEYKYLPLELGDYEIIIMSTNKNHSLAGSKYNERVQECEEAVKRLNKKLDINKLGELDSDTFDQYTYLIDDDTLIRRARHAVSENERTKKAIDAMEKGDLEELGRLINASHVSLKYDYEVTGKELDTLAENAWNQPGCLGARMVGGGFAGSAIAIVKKSEAENFKKNVGKIYRDKIGYDASFYDAEVVDGPHKL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PSEPU
Sequence: MAAETASGYIQHHLQNLTYGQLPDGSWGFAHSAAEAKAMGFWAFHLDTLGWSVALGLIFLLIFRMAAKKATSGQPGGLQNFVEVMVDFVNGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLIPVDWIPQLAILISGDPHIPFRAVSTTDPN
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NS1_I79A7
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNITLKANFSVIFDRLETLILLRAFTDEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: GLNB1_METTH
Sequence: MKTMRKITAIIRREKLEDVKDALELMGIHGMTVSDVKGRGQQMGIRESYRGMDYCVDLLPKVQLEIVVDSEDLERTVEAISENARTGDVGDGKIFVTDVIDVVRIRTGEHGRDAI
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen regulatory protein P-II 1.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: TAP_ORNMO
Sequence: YNRLCIKPRDWIDECDSNEGGERAYFRNGKGGCDSFWICPEDHTGADYYSSYRDCFNACI
What is the function of this protein?
TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
What are the official names of this protein?
Tick anticoagulant peptide, TAP.
Protein: THIG_PHATC
Sequence: MTNNLDKLKIGNKSFNSRLMLGTGKYRTTQSAIASIEDSNCDIVTVAIRRLPVNLKNDNINFLNKLDWNKLWLLPNTAGSQTAEEAIRMAFLGHELACQVGQEDNFFVKLEVISDPKYLLPDPIGTLKAAEFLIRKGFTVLPYINADPMLALHLEDLGCATVMPLASPIGSGQGLNNLANIKIIIENASVPVIIDAGIGTPSEATQAMELGADGVLLNTAVAQSKNPSQMASAMRLGVQAGRLAYLAGRMEKKYYADASSPLEQISKLI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPB2_BRASB
Sequence: MADASHDTQVSGHLTAIHGSVVDVRFPQGVLPALNEGIVIDRDEPTPVLAEVQQHLDPVTIRAVALGNTAGLSRGVSARALGTPIQTPVGDAVLGRLLNAVGKPADRGPELPPSTVFRPIHASAPALNRLGASQEIFHTGIKVIDLLAPLVKGGKAAMFGGAGVGKTVLIMELIRTTVERYSGISVFAGIGERSREGHELLLELKQSGVLPRTALVFGQMNEPPGARWRAGLTALTIAEHFRDVQHENVLLLIDNVYRLVQAGGEVSGLLGRLPSRVGYQPTLASEIAELQERIASVAGAAITSIQAVYVPADDFTDPAVAEIFSHLDSSIVLSRQMASEAMYPAVDPLASSSTLLDARLVGEGHYRTAQEVRKTIAHYRDLQEIIALLGIEELSAIDRQAVKRARRLMRFLTQPFMVTVAFTGKEGRTVEVADTLAGCRAILDGEADNWAESSLYMIGVLEEARERERASAKAMS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IZUM1_MOUSE
Sequence: MGPHFTLLLAALANCLCPGRPCIKCDQFVTDALKTFENTYLNDHLPHDIHKNVMRMVNHEVSSFGVVTSAEDSYLGAVDENTLEQATWSFLKDLKRITDSDLKGELFIKELLWMLRHQKDIFNNLARQFQKEVLCPNKCGVMSQTLIWCLKCEKQLHICRKSLDCGERHIEVHRSEDLVLDCLLSWHRASKGLTDYSFYRVWENSSETLIAKGKEPYLTKSMVGPEDAGNYRCVLDTINQGHATVIRYDVTVLPPKHSEENQPPNIITQEEHETPVHVTPQTPPGQEPESELYPELHPELYPELIPTVAQNPEKKMKTRLLILLTLGFVVLVASIIISVLHFRKVSAKLKNASDEVKPTASGSKSDQSLSQQMGLKKASQADFNSDYSGDKSEATEN
What is the function of this protein?
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg (PubMed:15759005, PubMed:24739963, PubMed:27309808).  The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:15759005, PubMed:24739963, PubMed:27309808).  The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PubMed:15759005, PubMed:24739963, PubMed:27309808).
What are the official names of this protein?
Izumo sperm-egg fusion protein 1, Oocyte binding/fusion factor, OBF, Sperm-specific protein izumo.
What is the protein family that this protein belongs to?
Belongs to the Izumo family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein. Note=Localizes initially to the acrosome membrane of the sperm head (both outer and inner acrosomal membranes). During the acrosome reaction, translocates to the plasma membrane.
Protein: ISPH_SYNR3
Sequence: MDTRAFKRSLHHSERYNRRGFGRAEEVAGSLEQAYQSELIQSIRENGYELREGRVTIRLAEAFGFCWGVERAVAIAYETRRHYPTERIWITNEIIHNPSVNAHLVEMNVLFIPVEEGVKDFSGVESGDVVILPAFGATVQEMQLLNERGCHIVDTTCPWVSKVWNSVERHKKNSFTSVIHGKVKHEETLATSSFAGTYLVVLDLEEAQLVCDYILGNGNREAFLKRFAGATSPGFDPDRDLSRIGVANQTTMLKSETEDIGRLFERTLLRRYGPTDLNDHFLAFNTICDATQERQDAMFSLVDEPLDLMVVIGGYNSSNTTHLQEIAVSRGIPSVHIDAPERIGPGNAVEHKPLGQDLERLEPFLPEGDLRIGITSGASTPDRVVEGVIDRLLQLAEAGQIAAEIA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ALGK_PSEAE
Sequence: MKMPILPPLPLASRHLLLASAIALAAGCAGLPDQRLAQEALERGDLATAQSNYQALAAMGYADAQVGLADMQVASGDSAQQAKAEKLYREAAQTSPRARARLGKWLAAKPGASDAEHREAERLLSQAFEQGEDSALVPLIVLYLQYPQSWPEIDPQQRIDQWRARGLPQADLAQIILYRTQGTYAQHLGEIEQVCQRWLRRMDVCWYELATVYQMQGNAEKQKVLLEQLRAAYKAGRVPGERVDSVAGVLADGELGQPDPQTAQALLEEIAPSYPAAWVSLAKLLYDYPDQGDLEKMLGYLKNAQDAAQPRAELLLGRLYYDGKWAPQDPRKAERHLLKAAASEPQANYYLGQIYRRGFLGKVYPQKAVDHLILAARAGQASADMALAQLWSQGRGIQPNRVNAYVFGQLAVQQQVPQASDLLGQIEAQLPPAERSQAQQLLKREQQSRGNNWQATVSLLQSQDSPINEEEPESL
What is the function of this protein?
May be involved in the polymerization of mannuronate to alginate.
What are the official names of this protein?
Alginate biosynthesis protein AlgK.
What is the protein family that this protein belongs to?
Belongs to the AlgK family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: FTSB_CROS8
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVADDVAVQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDATKRAGGPAQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CCD80_MOUSE
Sequence: MMWKMGPHFTTLLAMWLVCGSASHSPALDSDSHTGRKVPLVSPISSRSARYLRHTGRSGGVEKSTQEEPNPQPFQRRKSVPVLRLAHPTMRPPPSGINGVPVRPEVRPIARSSAREMVRDEGSSARTRMLRFPSGSSSPNILASFAGKNRVWVISAPHASEGYYRLMMSLLKDDVYCELAERHIQQIVLFHQAGEEGGKVRRITNEGQILEQPLDPNLIPKLMSFLKLEKGKFSMVLLKKTLQVEERYPYPVRLEAMYEVIDQGPIRRIEKIRQKGFVQKCKASGIEGHVVQEGNEGGGGAGGTGLGGDKRKEDPRRTQVHPTREAPRKQATSKAATPQPPPTPRATTLPPAPVTTATRATSRVVTIAARPTTTTAYPATQRPWTSRLHPFSVSHRPPATAEVTTARGPSVSEQLYPLPRKEQQREKPQATRRPSKATNYGSFTATPPPTLWEVSARVVGTSRFRDNRTDKREHGHQDPNAVPGPHKPVKGKLPKKKDRILSNEYEDKYDLSQPTSSQGEEERQVDSVPSQNAKESKKLEKLEKPEKEKKKKGKSAKQDKLLKSEKQAKKAEKKTKQEKDKNKKKKAGKTEQDDNQKPTAKHLAPSPKKSVADLLGSFEGKRRLLLITTPKAENNMYVQQRDEYLESFCKMATRRISVVTIFGPVNNSSMKIDHFQLDNEKPMRVVDDDDLVDQHLISELRKEYGMTYDDFFMVLTDVDLRVKQYYEVPIAMKSVFDLIDTFQSRIKDMEKQKKEGIACKEDKRQSLENFLSRFRWRRRLLVISAPNDEDWAYSQQLSALNGQACNFGLRHITILKLLGVGEEVGGVLELFPINGSSIVEREDVPAHLVKDIRNYFQVSPEYFSMLLVGKDGNVKSWYPSPMWSMVIVYDLIDSMQLRRQEMAIQQSLGMRCPEDEYAGYGYHSYHQGYQDGYQDDYRHHESYHHGYPY
What is the function of this protein?
Promotes cell adhesion and matrix assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 80, Up-regulated in BRS-3 deficient mouse.
What is the protein family that this protein belongs to?
Belongs to the CCDC80 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.