PharMolix/UniProtQA huggingface dataset:
Protein: KAD_THESQ
Sequence: MMAYLVFLGPPGAGKGTYAKRLQEITGIPHISTGDIFRDIVKKENDELGKKIKEIMERGELVPDELVNEVVKRRLSEKDCERGFILDGYPRTVAQAEFLDDFLKNQNKELTAAVLFEVPEEVVVQRLTARRICPKCGRIYNLISLPPKEDELCDDCKVKLVQREDDKEETVRHRYKVYLEKTQPVIDYYDKKGILKRVDGTIGIDNVIAEVLKIVGWSDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHT17_ARATH
Sequence: MAGDQLNVLNALDVAKTQWYHFTAIIIAGMGFFTDAYDLFCISLVTKLLGRIYYHVDGSEKPGTLPPNVSAAVNGVAFCGTLAGQLFFGWLGDKLGRKKVYGMTLMVMVLCSIASGLSFGSNPKTVMTTLCFFRFWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILTGGIFAIIVSAAFEAKFPAPTYQIDALASTVPQADYVWRIILMVGALPAAMTYYSRSKMPETARYTALVAKDAKLAASNMSKVLQVEIEAEQQGTEDKSNSFGLFSKEFMKRHGLHLLGTTSTWFLLDIAFYSQNLFQKDIFSAIGWIPPAQTMNAIQEVFKIARAQTLIALCSTVPGYWFTVAFIDVIGRFAIQMMGFFFMTVFMFALAIPYDHWTHKENRIGFVAMYSLTFFFANFGPNATTFVVPAEIFPARFRSTCHGISAASGKLGAMVGAFGFLYLAQSPDKTKTEHGYPPGIGVKNSLIVLGVVNLLGMVFTLLVPESKGKSLEEMSGENEQNDESSSSSNNNSNNAVSTA
What is the function of this protein?
High-affinity transporter for external inorganic phosphate.
What are the official names of this protein?
Probable inorganic phosphate transporter 1-7, AtPht1;7, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL24_ASHGO
Sequence: MKVEIDSFSGAKIYPGRGTLFVRGDSKVFRFHSSKSASLFHQRKNPRRIAWTVLYRRHHKKGITEEVAKKRSRKTVKAQRAVVGASLELIKERRSLKPEIRKAKRDEKAKADKEKKKADKAARKADKAKSAATQASKISKQQAKGAFQKVAATSR
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: YIDC_MARSD
Sequence: MDNKRVILAVALSFAVLLGWQFLFPPQPQQPAPAQQEQTAQPNQAVDSSVAGPVSNQLPDPASTSAIVSAKGTRLTVETPLYSAVINSQGGLLESFKLKKFKATIDADSPDVDMVGTNALDKAPMGLILNGIATWANGVWGYEGANLNLEGDKLGTLIFRGDVEGFRIERRLTFHADNYLIDEDVRVINKSNPSGMGRIAFTTATKSLTAADDRYNPTRIAWFNAEGLVEESDRDTLSETGVTESGKVEWAAIDSNYFILALVPGADSVTMKGKLQDDIFRIAAEQNVSFDKDIERKLACSYYFGPMDAQLMAKVPGELSKAIDFGWFDIIAKPLVVALEWFHQYTNNYGIAIILLTIVIKILFWPLSHKSYKSMEQMKRLQPMMAKLREKHGDDREALNKEMMQLYKTYNVNPAGGCLPMLLQIPVFFGLYKALMGTVALRHADFVHFLPFTDIVWLADLSAKDPLYITPIVMGATMFLQQKMTPSAGDPTQQKIMMFLPLVFTFMFLNFPSGLVVYWMVNNVLSIAQQWMMMRNVKN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASTA_SALEP
Sequence: MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: GLYA_ACIBT
Sequence: MFANISISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGGCEFVDVIEQMAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSAYSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSGLILAKANEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDFKAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITVNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVIDSKGDEKVIADVKAKVEAVCAKFPVYAK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAFA_GEOOG
Sequence: MERRIFGIETEYGVTCTFRGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGSRLYLDVGSHPEYATAECDDLSELVVHDKAGERILEGLLVDAEQRLAEEGVTGDIYLFKNNTDSAGNSYGCHENYLVGRHGEFSRLADVLIPFLVSRQIVVGAGKVLQTPRGAIYCISQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMNETTTLLKVAVTDLVLRMIEAGVPIRDMTLENPIRAIREISHDMTGRRKVRLANGKEMSALEIQSEYHSRAAEFVDREGFGPVHRQMLELWGRVLKAVDTGDLSLIDREIDWATKYQLIERYRAKRDLPMSSPRIAQMDLAYHDISRTRGLYYLLERNNQVDRVAHEPRVFEAKNVPPQTTRARLRGEFIRRAQEKRRDFTVDWVHLKLNDQAQRTVLCKDPFKAVDERVDKLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: EFCB7_HUMAN
Sequence: MAISPRSDATFSSQKSTPSESPRTKKFPLTEEEIFYMNCRAAYLTVFKSSLENIISKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILRKEKPTSKAELLKSFKQLDVNDDGCILHTDLYKFLTKRGEKMTREEVNAIINLADVNADGKFDYIKFCKLYMTTNEQCLKTTLEKLEVDSKLMRHQFGNHIEGSPERDPSPVPKPSPKITRKTDPETFLNKGDTRSSLLSATRKFKTSVSFTVTMGANGNRNSKLMEPNLIKDWQHMQSKGCFFLEEDGEIISHQYRMQIAQRSMVYLTIKPLNLSQVEGKPSPWLSVDTALYILKENESQANLQLVCFTELRNREVFGWTGELGPGIYWLIPSTTGCRLRKKIKPVTDEAQLVYRDETGELFLTKEFKSTLSDIFEVIDLDGNGLLSLEEYNFFELRTSGEKCDEDAWAVCRENFDTKRNELTRQGFMDLNLMEANDREGDPCDLWVTLHSMGYNKALELTEACPFVIDIYAEKCKPKIKAVHMEACSGQLEKAICKSVLSNGDAKVMDGYENIIVHTYSCDTWITSVIENKSDEKVIIHISNELSKNCINNRGLNIFAVEVGPKSTMVCQHVMPLNERQEWIYYCIYSLIS
What is the function of this protein?
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling.  Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia.
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 7.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner.
Protein: Y339_CHLMU
Sequence: MNRDNTIAWAVDDLCVNYDHSDVLCHIAFSLPSGAMAAIIGPNGAGKSTLLKASLGLIRASSGQSLFFGQKFAKVHQRIAYMPQRASVDWDFPMTVLDLVLMGCYGYKGMWNRISTGDRREAMNILERVGLADFANRQIGKLSGGQQQRAFLARSLMQKADLYLMDELFSAIDMASYRMVVDVLQDLKKEGKTIVVIHHDLSNVRQLFDHVILLNKHLVCSGSVEKCLTKEAIFQAYGCELELLDYTLKLSRGKYQGSC
What is the function of this protein?
Part of an ATP-driven transport system TC_0338/TC_0339/TC_0341/TC_0342 for a metal.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Probable metal transport system ATP-binding protein TC_0339.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FLHF_TREPA
Sequence: MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQSSVHEIPSVQSRTRVSAARVEDTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVPTSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIELLLEENDFSFSFIRKSIARLKDELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAFYFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQETDVVFVDTEGRSPVDGQNIERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALFEYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVPSNLEKASVNLLLSKLKGFKLLAEEMGNDYGDYGSKER
What is the function of this protein?
Necessary for flagellar biosynthesis.  May be involved in translocation of the flagellum (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhF, Flagella-associated GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL29_RHOP5
Sequence: MADMKSDDIRAMSEDQMDEAILGLKKERFNLRFQRATGQLENTSRLREARREIARIKTIAAQKRAAKK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL35_BACVZ
Sequence: MPKMKTHRGSAKRFKKTGSGKLKRSHAYTSHLFANKSQKQKRKLRKGAIVSAGDFKRIKQQLANIK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: KAD_PSEF5
Sequence: MRVILLGAPGAGKGTQAKFITEKFGIPQISTGDMLRAAVKAGTELGLKAKSVMDSGGLVSDDLIINLVKERISQADCVNGFLFDGFPRTIPQAEALVKAGVELDNVVEIAVDDEEIVQRIAGRRVHEASGRVYHTVYNPPKIAGKDDITGEDLVQRKDDTEETVRHRLSVYHSQTKPLVEFYQQLAATQGKPKYSHIPGVGSVEVITGKVLEALS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SHEAM
Sequence: MSNIPSELKYASSHEWIRKEDDGTYTVGITEHAQELLGDMVFVELPEVGDTVSAGEDCAVAESVKAASDIYAPISGEVIAVNESLEDSPELVNSDAYGDGWFFRIKPSDESELDSLLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PA24A_DANRE
Sequence: MSNIIVEHQYSHRLKLTVVRAENVTKGAFGDLLDTPDPYVELSVPTTPESRKRTRHINNDINPKWNETFEFILDPNQSNVLEVTLMDANYVMDETLGTAKYSLSKLKVAQMEHVTLSIGKTTKVFLDLLLEVCASTDLRFSMTLCDQEKLFMQTRRDRVMLSIKKLLKMENPRFLPSSPREVPTIAILGSGGGFRAMVGFSGVMKALYESGVFDCATYVAGLSGSTWYMSMLYSHPEFPAKGPGDINKELMNRVSNNPLKLLLPQNINRYVKALWKKKSAGQPVTFTDIFGMLIGETLIPGRMNIKLSSLKGKINEGQSPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMSPGLFGSKFFMGSVVKQYEENPLHFLMGVWGSAFSILFNRVLGVKETTSSSTMEEELEQIKPEHIVGDDSADNEEETQRGGTESADAEDERQRHAQASWVQRMLTSIMGDTTLFTTREGRAGKVHNFMLGLNLNSTLPFSPFSGITHQTSLEEEVDAVTDPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRCQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMNKLPFPKIDSKVFDREGLKECYVFKPAKGDKNCPTIIHFVLANINFRNFKAPGVPRDSDKDIEFGDFDIFDEPASPYSTFNFKYNNQAFKRLHDLMEFNTLNNIEVIKEAIKDSILLRRENPARCSVSLSLSEIENKKFLKRDNSIAKRPT
What is the function of this protein?
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid.  Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium- dependent fashion.
Protein: HSLO_STRA3
Sequence: MDKIIKSISTSGSFRAYVLDCTETVRTAQEKHQTLSSSTVALGRTLIANQILAANQKGNSKVTVKVIGDSSFGHIISVADTKGNVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVVITDYATGQPYTSTTPLITGEIGEDFAYYLTESEQTPSAVGLNVLLDDEDKVKVAGGFMLQVLPGASDEEISRYEKRIQEMPSISSLLESENHIESLLSAIYGEDDYKRLSEDSLAFYCDCSKERFEAALLTLGTKELQAMKDEDKGVEITCQFCNQTYYFTEEDLEKIINDSIK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_STRSV
Sequence: MKPSIYSLTRQEMIEWAEAQGEKKFRAAQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVMGIGEPFDNYDNVLKFVRTVNDDKGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVSLHAPNNDLRTSIMRINRSFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQAKELAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVMAFYDTLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDREKALVENVQP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y979_YERPA
Sequence: MPQSSRYSDEHVEQLLSELVSVLEKHRTPTDLSLMVLGNMVTNLINTSIAPAQRKVLARSFAEALQASVREDKAH
What are the official names of this protein?
UPF0352 protein YPA_0979.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: TBCC_SCHPO
Sequence: MSEKFVELRKEFLTKLYKSTPSEQTSRSEKETWLEEKSKYLGEMTRELNEVQDQIAPYDRRVCMEQLVDLTRRLQQIRHDILPRQPFRFQRALHVKSSQKPVKNITVNAEAPEVYFENDTLYLANLKNQNIGDNVIPYPNNKAVKVSAKSLRSCNISISNCSSVNLHNATKCNFTFPTIQGSIHLSDINDSTICVSCHQFRLHHSTNLRVHLRCKTSPVIEESKEISFSYKDEHPILDFTWARSDPSPHFRITSDLFDA
What is the function of this protein?
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone C, Tubulin-folding cofactor C, CFC.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PSBK_PINTH
Sequence: MFNIFLDDAFIHSNNPFFGKLPEAYAISDPIVDVMPIIPVLSFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: UNG_VIBVU
Sequence: MTQQLTWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDPYHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLEAWAKQGVLLLNTVLTVEQGKAHSHASLGWETFTDKVIEAINQHQQGVVFLLWGSHAQKKGRFIDRHKHVVLTAPHPSPLSAHRGFLGCKHFSQANQHLLDQGKQAIDWQLPLSL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGPRT_MYCLE
Sequence: MLVAQSFSAINPGPTAELYLGDIKSVMLTQEQIQARIAELGAQIGHDYRDRSPASDQDLLLVTVLKGAVIFVTDLARAIPLPTQFEFMAVSSYGSSMSSSGVVRILKDLDRDIHDRNVLIVEDVVDSGLTLSWLLRNLATRRPQSLQVCTLLRKPDALRANVDITYVGFDIPNDFVVGYGLDYDERYRDLPYIGMLDPRVYQQ
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE2R4_HUMAN
Sequence: MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2).  The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.  Has a relaxing effect on smooth muscle.  May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
What are the official names of this protein?
Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSP_BARHE
Sequence: MLERPFFSRHIGLRPDEKQKMLDIVAVDSIDTLVSQALPHSIHLGRPLNLPKAVSEGQALEELSKMMERNYLHKSFIGQGYHGTYVPPVILRNLFENPAWYTAYTPYQAEISQGRLELLFYFQTLISELTGLPVAAASLLDEATALAEAITVAFRFTREKKMKISLQSLLHPQILSVVQTRAETQGLQVSKNSEICSDTAAIVLSWPDTKGSFNDYSEVIKEAKAKGALVIVVADPLALTLMEAPAKWGADIVVGSMQRYGVPMGFGGPHAGYLAVSDALTRLIPGRIVGQSVDTKGRVGFRLALQTREQHIRRDKATSNICTAQALLANMATAYAVWHGPQGLQEIAQRVHHLTCRFVGGLEAVGISCEGEYFFDCVSIVVKGKAREIACQAKAGGRLIRVLDDDRVVINFDELSTQEDAHALAQLFGAGLVDQASPRLMGKGRDTTFLSQPFFHAVHSETDMMRFLRRLSDKDLALDRAMIPLGSCTMKLNAAAELMPVSWPTVANIHPFASREDAVGYQEMIHQLNAWLCEITGFAQVSFQPNSGAQGEYAGLLAIRRYHQSRGEHQRTLCLIPASAHGTNPASAHMAGMEVVVVKCLNDGDVDLDDLKMKAQLYKERLAALMITYPSTHGVYEESIKDICSLIHENGGQVYFDGANLNALVGLARPADIGADVCHMNLHKTFAIPHGGGGPGVGPIGVVEHLKPFLPGHEQEGTTHAVSAAPYGSASILVITWMYIRMMGAEGLKYATQTAILNANYIAARLSQVYSILYRGKHGRVAHECIVDTRVLKEQYGVSVDDIAKRLIDYGFHAPTMSFPVPGTLMIEPTESEPKAEIDRFCDALLSIAEEAKKIGSGVWPKDDNPLVHAPHTLVDTLDDTWARPYSRQEAAFPNCSLDPANKYWPPVSRIDNVAGDRMLICSCPPLGNTY
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PRMA_BACVZ
Sequence: MKWSEISIHTTHEAVEPISNILHEAGASGVVIEDPLDLMKERENVYGEIYQLDPNDYPDEGVIVKAYLPINSFLGETVDGIKETINNLLLYDIDLGRNTITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWETYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERIVQKGDRVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNVKLNKVSDTAEVKQNNLLDGITGEHDVIVANILAEVILRFTSQAYDLLKDGGHFITSGIIGQKKQEVKEALEKAGFTIIEILSMEDWVSIIAKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFSD6_HUMAN
Sequence: MADDKVAILTDDEEEQKRKYVLADPFNGISREPEPPSNETPSSTETSAIPEEEIDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCVPKIRPTTHPTNASHQLTILPTNSSFTSFLTISPKMREKRNLLETRLNVSDTVTLPTAPNMNSEPTLQPQTGEITNRMMDLTLNSSTATPVSPGSVTKETTTVIVTTTKSLPSDQVMLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFKNDDSKGKEVEIPQVERNNSTESSEETPTTTSHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRIEPRLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQIKEMMQLTRDNRASEIQPLQGTNENRENSPAGRAQPVPCETHSDPSRNQPSPDAAASQTQTSPAHPSVDPCTEESEEQQAQLAAGGH
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 6, Macrophage MHC class I receptor 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MFSD6 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RBSD_MARSD
Sequence: MKRTGLLNSELSYIISKLGHFDALTVCDAGLPIPEGVQRIDLAVSEGIPSFIDVVKAVLMEMELESVELAEEFKDVSSDRHDELISVLEMESAQRGKDIPVDYVRHVNFKLNTKKSVAIVRTGEFTPYANITFKAGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPS_CROS8
Sequence: MGTAKLVKTKASDLLYTRNDVADSDKKATIELLNRQVVNFIDLSLITKQAHWNMRGANFIGVHEMLDGFRTALTGHMDTIAERAVQLGGVALGTTQVINSKTPLKSYPLDIHSVQDHLKELADRYAIVANDVRKAISEAQDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.