PharMolix/UniProtQA huggingface dataset:
Protein: AROC_ALKOO
Sequence: MLRYLSAGESHGKGLIAIIEGLPSNIPMDINRINADLGRRQQGFGRGNRMKIEKDRVEILSGVRDGKTLGTPLTLMIENLDYKNWTSIMSVEKLEKQNIIVEPRPGHGDLVGSLKYNHKDIRNVIERTSARDTAIRTAIGAVVKQFLSIFDIEILSHVISIGRAHYVPFVEDLFQYKSQIEASPVRCLNPTIEERMMGEIQRAKETGDSLGGVFEVIVRNVPIGIGSYAHFDRKLDGILAQGLMSLQAIKAVEIGNGIEGSSKMGSQFHDEIKYSEAKGYYHDTNRAGGIEAGVSNGEDILIRGYMKPIPTLMKPLKTVDMGTKEVKEAIIERSDNCAVPSAAVVAEGICAFAIAKEFLEKFRGDSIEEVEWNYERYMNYLRSR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PSAM_SYNSC
Sequence: METVLSAPEVFIALVVAAHAAVLALRLSISLYEA
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PEX6_RAT
Sequence: MALAVLHVLEPFPTETPPLAVLLPPGGPWPVTGVGLVLALRPASESPAGPALLVAAVEGSGAQCEQRGPGPPPLLVSRTLLRVLALSPGARVRARPVRRPPALGWALLGTSPGPGLGPRVGPLLVRRGETLPVPGSRVLETRPALQGLLGPGTRLAVTELQGRTKLDPESRDHNHPPPPPVVSSFAVSHSIRQLRGVLGGTGDALGVSRSCLRSLGLFQGEWVWVARVGELPNTSQPHLAQVQVLEPRWDLSARLGPNSGQPGEPLADGLVFVPATLAFNLGCDPLEVGELRIQRYLEDSTAAEDKGSCSLLPGPPFARELHIEVLPSPHCGVNGKYDHVLYQHFHTPRVVQEGDVLCVSTAGQVEILEGSLERLPRWREVFFKVKKTVGEAPDGPASAFLADTTHTSLYLAGTTLSRVPPLPSGRSPPWDSLSPPGLEALVNELCAVLKPHLQPGGTLLTGTSCVLLQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRTVETKLQTTFSRARRCRPVVLLLTALDLLGRDRDGLGEDARVVATLRHLLLDEDPLSRCPPLMVVATTSRVQDLPTDVRTAFPHELEVPVLSESQRLSVLQALTAHLPLGQEVNLSQLARRCAGFVVGDLYALLTHASRAACTRIKAAGLAMSEEDEGELCAAGFPLLAEDFGQALDQLQTAHSQAVGAPKIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQLRVLSAITRKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEGLEPRSSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFAAC
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6, Peroxisome assembly factor 2, PAF-2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane. Cell projection, cilium, photoreceptor outer segment. Note=Associated with peroxisomal membranes. Localized at the base of the outer segment of photoreceptor cells (By similarity).
Protein: MCM7_YEAST
Sequence: MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDIDLQDA
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  Once loaded onto DNA, double hexamers can slide on dsDNA in the absence of ATPase activity.
What are the official names of this protein?
DNA replication licensing factor MCM7, Cell division control protein 47, Minichromosome maintenance protein 7.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL31_SERP5
Sequence: MKQGIHPKYEEVTANCSCGNVIKIRSTVGHDLNLDVCGECHPFYTGKQRDVATGGRVDRFNKRFSVPGAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RNPA_MICLU
Sequence: MLPRDRRVRTPAEFRHLGRTGTRAGRRTVVVSVATDPDQTRSTSPSAPRPRAGFVVSKAVGNAVTRNRVKRRLRAVVAEQMRLPPLRDLPVLVQVRALPAAAEADYALLRRETVGALGKALKPHLPAASEHA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PSD_PELUB
Sequence: MLEKIFPKIHSEGYKFLAIAIIVTIFLYVLSTFLGLIGLVLSIWVYYFFRDPERISINDENYLTSPADGEVLMVHEVDGPKELGLEDRKFTKISIFMNVFDCHVNRTPCEGKISEILYKPGKFLNASLDKASEDNERNYYKITNTHGEEIIVVQIAGLIARRIVCESSKDQQLQQGERIGMIRFGSRADVYFENYESLVKVGQKTIAGETLLAKK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SNRPA_PIG
Sequence: MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPASKKAVQGGAAAPVVGAVQGPVPGMPPMTQTPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1 snRNP is the first snRNP to interact with pre-mRNA.  This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.  SNRPA binds stem loop II of U1 snRNA.  In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.  May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity).
What are the official names of this protein?
U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A.
What is the protein family that this protein belongs to?
Belongs to the RRM U1 A/B'' family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL25_PSET1
Sequence: MSNKTYVYNAELREQTGTGASRRLRREDKVPAIVYGANKEATSITLDHKDVIKAQESEGFYTQILTLNIGGESVETILKDIQRHPFKPKVTHLDFQRIDANQKLHTIVPIHFVGEDVVEKLGTTVVRQLTEIEISCFPKAIPDFVTVDVSKLVAGDSLHISDVALPAGVSSIDLAKGPGHDQSILIVKANKSAPTEDEAEDAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: BCHB_JANSC
Sequence: MKLTVWTYEGPPHVGAMRVATAMKGLHYVLHAPQGDTYADLLFTMIERRDHRPPVTYTTFEGRDLGEDTAGIFKVTCQEAYDRFKPQAIIVGASCTAELIQDDPGGLAETMQIPVPVIPLELPSYQRKENFGSDETFYQIVKSLARPMDRTPEVTVNIIGPLALGFRHRDDIEEVKGLLYEMGIGVNVVAPFDATPEDITRLGAAHANVLMYPEHAESAARHLERICGQPYTKTIPIGVAATHEFVAEVAQLCGVEPRKDLSRLRQPWWSKSVDSTYLTGKRVFLFGDATHVKAAARIARDEMGFEVVGLGCYNREFARSIRELAREFDVPALITDDYLEVEKAIEDASPEMILGTQMERHIGKRLGIPCAVISAPVHVQDFPARYSPQMGWEGANVIFDTWIHPLVMGLEEHLLSMFREDFEFHDEAGPSHHGGHSPKPSEAARTPDKVEERADPAPEAPQTGSDVMVWLSEAEKELKKIPFFVRGKARRNTEKFAADQGLQEISLDTLYEAKAHYAR
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: HYAST_HYAAR
Sequence: MRVLLILVSLAALAHAESFLKSKTGYQGVQTLPGFIGGSQPHLGGGIGGGRPFISQPNLGGGIGGGIGGGKPFIPQPNLGGGIGSTRPFPRPQYGDYGSRNSCNRQCPSTYGGRGICCRRWGSCCPTNYKG
What is the function of this protein?
Antimicrobial peptide.  Has strong antibacterial activity against the Gram-positive bacterium C. glutamicum (MIC=0. 4 uM) and the Gram-negative bacterium E. coli (MIC=12. 5 uM).  Has weak antibacterial activity against the Gram-positive bacterium S. aureus (MIC>50 uM) and the Gram-negative bacterium P. aeruginosa (MIC>50 uM).  Has antifungal activity against S. cerevisiae (MIC=12. 5) and C. albicans (MIC=6. 3 uM).  Has weak antifungal activity against the mold B. cinerea.  Presents chitin-binding activity.
What are the official names of this protein?
Hyastatin.
What are the subcellular locations of this protein?
Cytoplasmic granule.
Protein: ATP6_STAA3
Sequence: MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGB_CYACA
Sequence: MNNKSIRTQILIEALPYIQQFRGAIFVIKYGGAAMKDLISKERLIADIVFLSCIGLKLVCVHGGGPEINFWLNKMNVESKFHDGIRITDELTMQVVEMVLAGKINKELVSLLNNKGVKGVGLCGKDGTILTARKAQCGSIDMGLVGEIKSVDPYLILTLLKENYIPVIASVGADETGKTYNINADFVAGEIAASLGAEKLILVTNTSGILADVSQPESLIRDTNIMQLRQLLSRGIISKGMIPKVNCSIRSLAQGVRAVHIIDGTKPHSLLLEVLTNNGIGTRFLYKQSILLQLNCFSFSNVSI
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ULAG_SALTY
Sequence: MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPGGNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_DESVH
Sequence: MSSTLVLETTAYTLEQLIHLDAPQIALAGRSNVGKSSLVNALARRKQLAKTSSTPGKTRSVNYYRVEPEGFYIVDLPGYGYAQCSKEERKKWAKLIEKYIVSCKSLRGLAVLLDCRLDPQRLDVDLTSYARANNIPLLPVLTKGDKCKLRERSDRQKQWAVLLGGRKPLVTASMTGLGIADLWRELRALAAGGLSADDEAEDAPSDTSDAIDDVTA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CAH1_MACNE
Sequence: MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSEAKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSSNEYGSEHTVDGVKYSSELHIVHWNSAKYSSLAEAVSKADGLAVIGVLMKVGEANPKLQKVLDALHAIKTKGKRAPFTNFDPSTLLPSSLDFWTYSGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNPVPSQRNNRPTQPLKGRTVRASF
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase I, CA-I.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO8A2_MOUSE
Sequence: MQGALMPLPSLLLLLLGCGPRVSSGGGAGGAAGYAPVKYVQPMQKGPVGPPFREGKGQYLEMPLPMLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGTGKPGVHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITVPGKPGAQGAPGPPGFRGEPGPQGEPGPRGDRGLKGDNGVGQPGLPGAPGQAGAPGPPGLPGPAGLGKPGLDGIPGAPGDKGDSGPPGVPGSRGEPGAVGPKGPPGVDGVGIPGAAGVPGPQGPVGAKGEPGLRGPPGLIGPVGYGMPGKPGPKGDRGPVGAPGLLGDRGEPGEDGKPGEQGPQGLGGPPGLPGSAGLPGRRGPPGSKGEVGPGGPPGVPGIRGDQGPNGLAGKPGLPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGKVGEPGSAGPTGPPGVPGSPGLTGPPGPPGPPGPPGAPGALDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVRFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT
What is the function of this protein?
Macromolecular component of the subendothelium.  Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells.  Also a component of the endothelia of blood vessels.  Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity).
What are the official names of this protein?
Collagen alpha-2(VIII) chain, Endothelial collagen.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: ACP_XANCB
Sequence: MSTIEERVKKIVVEQLGVKEEEVTTSASFVDDLGADSLDTVELVMALEEEFECEIPDEEAEKITSVQQAIDYVKAHVKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD12_ORYSJ
Sequence: MGAPATAASGGGDDDDRDVVFEYLLCTEEDAASAGSFFQQLQGPAPAVSSSPSTTTATAPAAAGSCDDGGEEEEEEVWTVDVVAELIGGEAERSHSPRADYPGRLRSGRPADLAARADSVAWILKVRELYGMLPVTAYLAVSYMDRFLSLHRLPGNGWAMQLLAVTCLSLAAKMEETLVPSILDLQMEDARYIFEHRTIFRMELLVLDALDWRLRSITPFTFMYLFADKVDPNGKHIRELIHQATQVTLATIHDTEFLDHCPSSIAAAAVLCASSEIMQLVSIDHGTLVSWRIIGLDEEAIIRCYRLMQQLISSNNVGRESTEITMATTTTTATTAVSSEEVVSSSPPSKRRKM
What are the official names of this protein?
Cyclin-D1-2, G1/S-specific cyclin-D1-2, CycD1;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: MNME_HAMD5
Sequence: MSHTDTIVAQATPIGRGGIGILRISGCATKTVAKEILGKLPRARYAEYLAFKDPEGNILDQGIALYFPAPHSFTGEDVLELQGHGGPIILDLLLKAILNLPDVCVRIARPGEFSERAFLNDKLDLVQAEAVADLIDASTEQAARCALHSLKGTFSLRINQLIESLTYLRVYIEASMDFSDEEIDFLSDGKIETQLDRVIHDLDKVRSEARQGQLLREGMKIVIAGRPNVGKSSLLNALTGRETAIVTQIPGTTRDVLREQIQINGMPLHIIDTAGLRETEDPVEKIGIERAWNEIEQADRILFIVDGSTSSEKTIYPLWPEWEARLSRSRLPITLIRNKSDITGEDVALTETEEGTFISLSARTGEGIDLLREHLQQTMGFSGNMEGGFLARRRHLEALENAAQYLLSARQKWSSGNFLSELLAEELRLAQQVLSEITGQVSSNDLLGIIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST5C_DROPE
Sequence: MLAARLIILLSFYWLSASAIDPADPLFVDLPHGKIRGRDNGFYYSYESLPYAEPPVGELRFEAPQPYKQQWTDTFDATQPPVTCMQWNQFIFGDNKLAGVEDCLTVSIYKPKNTSQSSFPVVAHMHGGAFMFGEARQNGHENMMREGKLILVKISYRLGPLGFASTGDAGLSGNFGLKDQRLALLWIKQNIASFGGEPENIIVVGHSAGGASVHLQMLREDFAQVAKAGISFGGNAMDPWVIHQSARGRTFELGRIVGCGQASDSTELKNCLKSKPAGEIVSAVHSFLVFAYVPFAPFGPVVESPDAPEAFISQHPVDIIKSGKFAQVPWAVTYNTEDGGYNAAVLLEKQASSGRELIFDLNDHWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDLQRLFTDILYKNATELALDLYRKHGKSPVYAFVYDNPANTGIGQFFSKRTDVHFGTVHGDEYFLIFENLARGPEMRSDEEIISRNFLNMINDFVVSGNGTMTFGNCVLQDNVGSNKFQLLSITKNGCENLQLESFP
What are the official names of this protein?
Esterase-5C, Est-5C, Carboxylic-ester hydrolase 5C, Carboxylesterase-5C.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_PROM0
Sequence: MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFKFKREIIAEDGCKGGPNKRSGASGQDTILKVPCGTEIRDIKTGIILGDLTKDKQSLTIAIGGRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLAEVGIIGLPNAGKSTLISVVSSARPKIANYPFTTLIPNLGVVRKMDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKILVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKMELVDDDYLQIITKKLEDLSKKKVLVISSSLKKGLSSLLSEVWKRI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_SYNSC
Sequence: MSQPSSDTQRQPAIVILDFGSQYSELIARRVRETEVFSVVLGYSTSAEELRRMAPKGIILSGGPSSVYAEHAPLCDPGIWDLGIPVLGVCYGMQLMVQQLGGVVEAATGKAEYGKAPLEVDDPTDLLTNVDNGSTMWMSHGDSVKALPEGFVRLAHTANTPEAAVAHLQRKLYGVQFHPEVVHSTCGMALIRNFVYHVCGCDPDWTTAAFIDEAVALVREQVGDKRVLLALSGGVDSSTLAFLLKKAIGDQLTCMFIDQGFMRKGEPEFLMDFFDRKFNIHVEYINARQRFIGKLEGITDPEEKRKIIGTEFIRVFEEESKRLGPFDYLAQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRKVGRSLGLPEEIVRRHPFPGPGLAIRILGEVTDEKLDCLRDADLIVRQEIKEAGLYHDIWQAFAVLLPVRSVGVMGDKRTYAWPIVLRCVSSEDGMTADWSRLPYDLMETISNRIVNEVKGVNRVVLDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RDRP_I77A4
Sequence: MDVNPTLLFLKEPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQQDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDRLTQGRKTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKRMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGHTQIQTRRSFELKKLWEQTRSKAGLFVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFSEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: DCTD_BPMD2
Sequence: MSRPDWDEYFLGIATAAAQRSDCERSKVGAVVVKDRRVRGTGYNGAPAGAAGCSTCPRRLSGAVPGVSDYSSGATRCVAVHAEANALLYCDREDLIGATLYVTREPCYACSNLIAASGIERVVYPKES
What are the official names of this protein?
Deoxycytidylate deaminase, dCMP deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: ARCH_PYRIL
Sequence: MKCGKPVDYRYGEHTADVLIQAYGCTLEEAFKNAAIALAELTYHTEKVEPRYAKEITIDYNDLEGLLFRWIDELLFLFDTEKFAISREIVLNLGKNDVYYIKAVLYGEPYDIEKHGFTGLIVKAMTFHMMEIRQIDDYWMLQYVVDV
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: TGL_BACLD
Sequence: MISVSGYRLRPEDIEKLNVSQTQRDIANRMLAMPSGYRYGSISELLFELRFREHTVKSARELINSGAKFATFSKTYGNEEFWRVTPEGALELKYRAPASKAIRNIFESGPSYAFECATAIVIIFYMALLKTIGDQTFDRNYQRIILYDWHYERLPIYTDKGNDYLPGDCLYFKNPEFDPSRPQWRGENAILLENNLYAAHGLGILSGETIIEKLNGLRKPHAQTSAYLLSQVTRVDIPALIQMIR
What is the function of this protein?
Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, Transglutaminase, TGase.
What is the protein family that this protein belongs to?
Belongs to the bacillus TGase family.