PharMolix/UniProtQA huggingface dataset:
Protein: LSRF_YERPE
Sequence: MADLDDIKDGKDFGIGIPQQNPAFTLKGSGSLDWGMQSRLARIFNPKTNRTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPAAANRPVVLRASGANSILTYLSNEAVAVAMEDAVRLNACAVAAQVYIGTEHEHQSIKNIIQLIDQGMRYGMPTMAVTGVGKDMVRDQRYFSLASRIAAEMGAQVIKTYYVDSGFERIAAGCPVPIVIAGGKKLPERDALEMCYQAIDQGASGVDMGRNIFQSDAPIAMLKAVHAIVHKNENAAAAYQLFLHEQN
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA1_GEOKA
Sequence: MEKIIVRGGNRLSGTVKVEGAKNAVLPVIAATLLATKGTSTIHDVPALSDVYTISEVLRYLGADVHIADETVTVDATGPLTVEAPFEYVRKMRASVLVMGPLLARNGRARVALPGGCAIGSRPIDQHLKGFEAMGASVKVGNGFIDAEVNGRLRGAKIYLDFPSVGATENIMMAAVLAEGTTVIENCAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDELVGTTHTVIPDRIEAGTFMVAAAITGGNVLVQGAVPEHLGSLIAKLEEMGVTVIEEESGLRVIGPEKLKAVDIKTMPYPGFPTDMQSQMMALLLKAEGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIINGPCQLQGAEVAATDLRAAAALILAGLAADGYTRVTELRHLDRGYVRFHEKLAALGADIERVHEETEQFDQIQTIQWNG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPHP_CORGL
Sequence: MQARIDATLNEHNRPEGSVRLLPVTKFHPVEDIKILQEFGVTAVGENREQEARAKALELPDMDFHMIGQIQSKKANSIARWAAAVHSVDSEKIAEALGRGVALALDRGDRTSDELPCFIQLSLDGDPSRGGTPLSQVTQLADCISDTTHLRFEGLMCVPPLGWGPEKAFSQARDVLSGLEEHFDRSLEFSAGMSGDLVAAIKHGSTIVRVGTEILGNRPLA
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: ENGB_DESHY
Sequence: MITIRKAEFVTSAVNIKGYPELTGPEIALAGRSNVGKSSLINKFINRRNLARTGNTPGKTQMLNFYRINDQWSFVDLPGYGYAKVSKEIKANWGKMMEEYFSRRENLRAVIQVVDIRHVPSVEDQEMHAFLRNRGIPVLVVATKADKISKGQWGKHLSQIAKALHIPDWHIIITYSAETGLGVPELHEAVEEILSMDNEDS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL5_BRAHW
Sequence: MSVLKDRYENEIKQSLLKDMNLSSTMAIPKIEKIIINMGVTQAVTDKKYVDSAVEELSQIAGQRAVVTRAKKSIANFKLRQGMPIGCRVTLRGERMYDFLERLIFIALPRVRDFQGIPRRGFDGNGNYNLGIKEHTIFPEISFDKTDAVKGLNITIVTTADNDDMARTLLERVGLPFRAAPKSQENK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FPG_SALAI
Sequence: MPELPEVETVRQGLAQWVTGRRIAEVEVRHPRAIRRHPAGAAHFADVLVGTTVRDVRRRGKYLWLPLDSGDAVIGHLGMSGQLLLQPGAAPDEAHLRVRFRFADDGPELRFVDQRTFGGLSVSAGGAEMPTEIAHIARDPLDPEFSEAAFVAALRRRRTEVKRALLDQTLLSGVGNIYADEALWRARLHGARPADGLTGPAALRLLGHVRDVLGEAIKEGGTSFDALYVNVNGESGYFDRALNVYGRADQPCRRCGTPVRREAFMNRSSYSCPRCQPRPRRALQASG
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: KAE1_HYPBU
Sequence: MVSVDTPSSLGKPRGDPRQLYRVGGWDEEIYVLGIESTAHTFGVGIASTKPPYILVSVRDTYHPPKGGIHPREAASHHARVASEVILDALRTVGLSIRDIDAVAVALGPGLGPALRVGATIARGLAAYYGKPLVPVNHAVAHIEIARLYTGLGDPVVLYVSGGNTVVAAYAKARYRVFGETLDIALGNLLDTFARDAGIAPPYIVSGLHIVDRCAEAASKPADLPYVVKGMDVSFSGLLTAALRLWTKAGSEDEKAAVCLGLREVAYGSVVEVTERALAHTRKKSVMLTGGVAASPILRNKVRSMASYHGAVADWPPPQLAGDNGAMIAWTGLLNYLAGITVDVEESVVKQRWRLDVVEIPWR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRO_SALFO
Sequence: MSTHKAALCKVQILKLFLISARCVRITRFYGVCGLSTSTPASSPKVCIVGGGPAGFYTAQHLVKTRTDVQVDIYERLPVPFGLVRFGVAPDHPEVKNVINTFTQTARHARCSFHGNVRVGKDVTVEELQEAYHAVVLSYGAEGNRTMGVPGEDLAGVYSAKDFVGWYNGLPRNRELRPDLSCETAVILGQGNVALDVARMLLSPVDILKKTDITQHALDALAESSVRRVLIVGRRGPLQVACTIKELREMVNLPGTRPEMEASEFEGIAETLKSLARPRKRLTELLLKAAIETPGEEELEKRNKAERAWGFRFLRRPLEVLPSTDLIRAAGIRLAVNRLEGDGEGVRAVATGEVEDVECGLVISSIGYKSLPIDPAVPFDGRKAIIPNTMGRVQQTAGLYCSGWVKRGPTGVIATTMNDSFDTARTLLQDIGKGTLDVSSVKPGSQGVSALLEKRGVKPVSFSDWEKIDSEETRRGETRGKPREKMLDVGEMLQVARA
What is the function of this protein?
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
What are the official names of this protein?
NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: CC127_RAT
Sequence: MNNLNDPPNWNIQPNPRADGGDGSKWNYALLVPMLGLAAFRWIWSRESQKEIEKARRAYHQQTAAFQQDLDAKYHAVISEHRRAVAQLSLELEKEQNRTTSFREALISQGRKLAEEKKLLEQERAQIIQEKSQRQPLRRAYLSCLEEEDEWQRRAQLVLKEVGEALEERQNIYCSLILPRSARQQLEKSLLVRTSADPVAADLEMATGLSDIFKHDKHCGDVWNTNKRQNGKLMWMYLKYWELLVELKKFKKIEKVILGK
What are the official names of this protein?
Coiled-coil domain-containing protein 127.
Protein: RNP3_THEKO
Sequence: MSEEEVSFSRDYFVEMDVRDEEAHELASDWFDEVVFTKKLVLEDPPDWGSLKEELKELRGKYGKVALLLVTRKPSLIREVKSRNLKALLYVQGGDMRINRMAIESGVDALISPWFGRKDPGFDHTLAGMAARRGVAIGFSLSPLLNANPYGRAQILRFMMKTWQLVKKYRVPRFITSSAESRWEVRGPRDLMSLGINIGMEIPEARASLNFYPRTIVWKL
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_FRATW
Sequence: MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNX_SALPK
Sequence: MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPAVDARWQAKFGRAMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIATLRAEGIKIGSCSGYPRAVMERLVPAAAGHGYCPDHWVATDDLAAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPGVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: Y2409_LEGPL
Sequence: MMVAHTAQQLDLREKLLTNGVHSLSDIELLAVFISSGNNKKSCLQLAYELTKHLGNLRNILNADLQSFKSIHGLGEVRYAQLQAAKEICHRSDFIDLQKEIRLSNTQQTYAFLKKRLRDYKNETFAALFLDNQHRIIAYEELFSGTINTATVYPRPIVERVLQLNAAALILAHNHPSGLSDASQQDLAITERIRDALDLVDARLLDHIVIGDNEVYSIFAENKWACN
What are the official names of this protein?
UPF0758 protein lpl2409.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MTNB_BACMK
Sequence: MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHDPLTFLITASGKDKTKTTPDDFLLVNHQGIPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATINIPIIENDAHIPTLGEKFRKHIQGDSGAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: EX7L_STRPZ
Sequence: MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQYFSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDGIGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQNRSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSAKENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLSLDTSRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH18_HUMAN
Sequence: MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANCWERCRPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLSSVETYSPETDKWTVVTSMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEHYNHHTATWHPAAGMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDCWTFMAPMACHEGGVGVGCIPLLTI
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis (PubMed:23213400).  The BCR(KLHL18) E3 ubiquitin ligase complex mediates the ubiquitination of AURKA leading to its activation at the centrosome which is required for initiating mitotic entry (PubMed:23213400).  Regulates light-and dark-dependent alpha-transducin localization changes in rod photoreceptors through UNC119 ubiquitination and degradation (By similarity).  Preferentially ubiquitinates the unphosphorylated form of UNC119 over the phosphorylated form (By similarity).  In the presence of UNC119, under dark-adapted conditions alpha-transducin mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light (By similarity).
What are the official names of this protein?
Kelch-like protein 18.
Protein: CCA_SHESM
Sequence: MKIYLVGGAVRDSLLNLPIKDKDFMVVGATPEQMLQLGYRQVGKDFPVFLHPKTQQEYALARTERKVGLGYGGFSCYASPEVTLEQDLLRRDLTINAIAQDEAGNLHDPFHGIADIEARQLRHVSAAFSEDPLRVLRVARFAARFHGLGFEIAPETMALMQHMSQTEELTALTPERVWQEVDKSLGGPHPEVFFEVLRQCGALKVLFPEIDALFGVPQPEKWHPEIDTGLHTMMVLAQSSSMTEEKAVRFAALVHDLGKALSPKEHWPKHHGHGQKGLPVIKSLCERLRVPNEYRDLALLVSDQHQNVHQAFELRSETIIKLFDKADFWRKPERLKQLLLACIADMRGRTGFEHQPYPQSDYLNACFLAANNVDVKAIIAAGFQGAQIKEVVNSKRIEMVAQVKQHWPGAQAKETP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RUSF1_MOUSE
Sequence: MADAASLRAPLCTEQFGSGAPRGCSAAADGSLQWDGARRWGWLSRAPIAKPGQHAGGGGGPWAALTALSGLRSVLLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATQAVLQGLGVGNAKASVSAATSTWLVKDSTGMLGRIILAWWKGSKLDCNAKQWRLFADILNDVAMFLEIMAPMYPIFFTMTVSTSNLAKCIVGVAGGATRAALTMHQARRNNMADVSAKDSSQETVVNLAGLLVSLLMLPLVSDCPSLSLGCFVLLTALHIYANYRAVRALVLETLNESRLQLVLEHFLQRGEVLEPASANQMEPLWTGFWPSLSLSLGVPLHHLVSSVSELKQLVEGHHEPYLLCWNKSRNQVQVALSQEAGPETVLRAATHGLILGALQEDGPLPGELAELRHQVQADPKKESWILVRETHQVLDTLFPKFLKGLQAAGWKTEKHHLEVDEWRATWPLSPEKKVL
What are the official names of this protein?
RUS family member 1.
What is the protein family that this protein belongs to?
Belongs to the RUS1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUOE_RICFE
Sequence: MSTNFTFDKKNLNLAEDIIKKYPPHGKRSAILPLLDLAQRQNGGWLPVPAIEYVANMLEMPYMRAYEVATFYSMFNLKRVGKYHIQVCTTTPCWLHGSDDIMKICEKKLGIKLKETTEDQKFTLSEIECLGACVNAPVVQINDDYYEDLTEEKMEKLIDEYSNDFKN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit E, NADH dehydrogenase I subunit E, NDH-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
Protein: COBS_MYCSS
Sequence: MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSALAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVLVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVA_RHOCS
Sequence: MIAKLTGLLDSTGLDWAIVDVGGVGYLVSASARTLRRLAAPGEAVSLLTEMWVSEDNIQLFGFADTEERDWFRLLTTVQGVGARVALNLLSALSPAELTNSIAAQDRTALCQADGVGPKLAARILNELKEKVASFGAPAPAAATAGKGGAAPAGPAGAVADAVSALVNLGYRRVEAFTAVNAVAQRLGPEAGVSDLIRAGLKELSP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FLGB_YERRU
Sequence: MLDKLDGALRFQQEALNLRAQRQEILSANIANADTPGFQARDIDFSSQLQKVMEQGRVNGSGMSLSLTAARHIPAQNIQPPDLDLLFRVPDQPSMDGNTVDMDRERTNFADNSLKYQTDLTILGGQIKGMMSVLQQG
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: Y5507_DICDI
Sequence: MEPVLTEREKMVTGLRYRFEDPELDQLRLRARRLNKQFNNLIGSDEDDGKKGPEIIKQLFGSTGEIVIVREGIKVSYGVNIHVGDKFFINHNCILNDDGPIRIGYGAMIGPNSQLYTATHPFEPSERIGGSDENFTKGITIGDNFWGGGNVIILPGVTLGNNVIVGAGSVVTKSFPDNSIIAGNPAKLIRMNIPTK
What are the official names of this protein?
Putative acetyltransferase DDB_G0275507.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: GOGC5_ARATH
Sequence: MAWFSGKVSLGGFPDLTGAVNKFQESVKNIEKNFDNALGFDDKSDSAAEDAASSMWPPAVDTKSLFDPVMSFMGNTSDEKPDTLEDSVRTENPSQIEQKEEEAGSVKLATEQAVSVEANKETNVRREADQADNPEVTETVVLDPKDDEPQSQILLEESSEYSLQTPESSGYKTSLQPNEKLEMTASQDSQPEQPKSEAEESQPEDSEAKEVTVENKDTVHSPVLDGQHKITYMDETTNEQEILGENLEGRTSSKNFEVSPDINHVNRIESPVAHPSLIFESDGSPYESSIPKRSSSDEISERIVDFVSREIDSRLDTSELNESQRSSSATNVSDSADVILELEKTKKEIKMLENALQGAARQAQAKADEIAKLMHENEQLKSVTEDLKRKSNEAEVESLREEYHQRVATLERKVYALTKERDTLRREQNKKSDAAALLKEKDEIINQVMAEGEELSKKQAAQEAQIRKLRAQIREAEEEKKGLITKLQSEENKVESIKRDKTATEKLLQETIEKHQAELTSQKDYYSNALAAAKEAQALAEERTNNEARSELENRLKEAGERESMLVQALEELRQTLSKKEQQAVYREDMFRGEIEDLQRRYQASERRCEELITQVPESTRPLLRQIEAMQETSYRTAEAWAAVERTLNSRLQEAESKAATAEERERSVNERLSQTLSRINVLEAQLSCLRAEQGQLSKSLEKERQRAAENRQEYLAAKEEADTLEGRANQLEVEIRELRRKHKQELQEVLLHNELIQKDLEREKASRLDLERTARINSSAVSEQLPIARQNSAFENGSLPRKLSSASSLGSMEESYFLQASLDSSDKFSEKRSMPEATMSPYYMKSITPSAYEATLRQKEGELASYMTRLASMESIRDSLAEELVKMTAECEKLRGEADRVPGIKAELEALRQRHAAALELMGERDEELEELRADIVDLKEMYREQVNMLVNKIQ
What is the function of this protein?
Golgi matrix protein playing a role in tethering of vesicles to Golgi membranes and in maintaining the overall structure of the Golgi apparatus.
What are the official names of this protein?
Golgin candidate 5, AtGC5.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm. Note=May be located to the trans-Golgi or trans-Golgi network (TGN).
Protein: PYRE_CHLPN
Sequence: MMNYEDAKLRGQAVAILYQIGAIKFGKHILASGEETPLYVDMRLVISSPEVLQTVATLIWRLRPSFNSSLLCGVPYTALTLATSISLKYNIPMVLRRKELQNVDPSDAIKVEGLFTPGQTCLVINDMVSSGKSIIETAVALEENGLVVREALVFLDRRKEACQPLGPQGIKVSSVFTVPTLIKALIAYGKLSSGDLTLANKISEILEIES
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: Y7291_DICDI
Sequence: MLSNGLKIDQEKKFFILIIIIINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNKNNNKNND
What are the official names of this protein?
Putative uncharacterized protein DDB_G0275565.
Protein: AAKB2_RAT
Sequence: MGNTTSERVSGERHGAKAARAEGGGHGPGKEHKIMVGSTDDPSVFSLPDSKLPGDKEFVPWQQDLDDSVKPTQQARPTVIRWSEGGKEVFISGSFNNWSTKIPLIKSHNDFVAILDLPEGEHQYKFFVDGQWVHDPSEPVVTSQLGTINNLIHVKKSDFEVFDALKLDSMESSETSCRDLSSSPPGPYGQEMYVFRSEERFKSPPILPPHLLQVILNKDTNISCDPALLPEPNHVMLNHLYALSTKDSVMVLSATHRYKKKYVTTLLYKPI
What is the function of this protein?
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3) (By similarity).
What are the official names of this protein?
5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Protein: ATPG_PSEF5
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQMRMAASRPYAERIRQVIGHLANANPEYRHPFMIDRAIKRVGYVVVSSDRGLCGGLNTNLFKALVKDMAVNREQGVEIDLCVVGSKGAAFFRNFGGNVVAAISHLGEEPSINDLIGSVKVMLDAYLEGRIDRLSVVSNKFINTMTQQPTVEQLIPLEATPDQELKHHWDYLYEPDAKELLDGLMVRYVESQVYQAVVENNAAEQAARMIAMKNATDNAGDLISDLQLIYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PARB3_DEIRA
Sequence: MTRREGLAALLGESAKLAQGPVVGHTSTLRVDQLRAGSQQPRRQFGTEGLTELAASIQSQGILQPLLVRAVGDTYEIVAGERRWRAAQLAGLTEVPVIVKSLTDQEAAVIALIENLQRENLNLIDEVEGKLLLVANALGIASEQARSRLNELLRNPVPEDVETLSAVFLPLGRESWQSFAKNKVRILNYPPPLVEALRQGMALTMATLIARAPENKQADLIAKVQQGAGRKEIVAEVERLCHRPTVRLEKRVAQALGNQKWLDRLDPQDAEAMQHWLSQMPRALQQEIGDN
What are the official names of this protein?
Probable plasmid-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.