PharMolix/UniProtQA huggingface dataset:
Protein: RL20_DESHY
Sequence: MARVKRGVTKHQRHKKVLKLAKGFRGAKSKLYRPANEQVMKSLAYAYAHRRDKKGDFRKLWIARINAAARLNGLSYSRMMNGLKIAGVSVNRKMLADLAINDAAAFTELVNVAKAQVSAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NO66_CAEBR
Sequence: MGKKNKSNGGGNTNNTPTKTPSKPPVKFNDKWASIENGEAKSASVSHYKEPSKEPKFVHPAKLAKEKKIFDGLDIPERVLAHGKVVEQNGGKKRRHREISPKMEAKKPKVESKSKDGVAAKKAHKHFTVSSEVVQSTYFFEEPDNGNEVTLVSNGKETTIEKTVILDEEVEDEEIDEEEFEDEEEVEDEEGMDEDETEIDESEMIVDPKDIERCIEFEDVDDEDEMEDEEEFEDEEEVEDEEVDDEEEEEVADEERGEEQEDEQEEEEEVSDEESVVSEMDADSDDEGFIAGKDREAHVISKDKAARTFAAKPVDFDAFPFNDQDSVVTASRAFGFMVSPCDVQTFFDKFYQSNVLVVHRKTPAYYGNLFSTTRFSELLEKHYLEYNMNINIAQYKDGIRTTLNGKGRVYPQIVKQHLHNLCSVQLVNPQTFDDRIWYLCEILQEQFGCFVGANTYLTPAGSSGFAPHWDEIDAFLLQVEGRKYWRVWAPESAEEELPLESSGNFTEDDMKGKEPVFEGWIEQGDMIYIPRGYTHQARTDKKVHSLHVTVSTGRQWSFANLMEKVIPEAVGALTEERHKLRRGLPIGLFDMGGVVDLDYSQEEHFTEKFKIVVDRHMSRLRNLVADHLLDSSVDSMTKEFMKQALPPILTDKEKKRSVIGLSTNLLGDDLIDFCANTKVKFIRKHTQRLLMESEDSCFISHRMNNSRLFEGRPETLVDFPSTGIDTYRVLWNAYPEWRTLDEIFSCRETKSNTRKEKLAAIQILFQMGVLLVKNPK
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.  Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
What are the official names of this protein?
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Histone lysine demethylase NO66, Jumanjic domain protein 1.
What is the protein family that this protein belongs to?
Belongs to the ROX family. NO66 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR9_STRPM
Sequence: MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNLYPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHMNPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: YEV1_YEAST
Sequence: MGLSRWHDKNSRPAEEKSEEMQQDAHYYALAASDSLNASVSNEYGNQVMNSFWKVGIDSPYVDDEAIRNRDVENNLPSLKQSVYNANEPNATSSAFSTASYAHETFDFRNLKLR
What is the function of this protein?
May be involved in phosphatase regulation and/or generation of precursor metabolites and energy.
What are the official names of this protein?
Uncharacterized protein YER121W.
Protein: AAPAT_RICCN
Sequence: MSIISTRLSSIKPSPTLAVVKKTLELKKAGVDIITLGAGEPDFDTPDNIKEGAIKAIKDGFTKYTNVEGMPLLKQAIKDKFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDQGDEVIIPAPYWVSYPDMVALSTGTPVFVNCGIENNFKLSAEALERSITDKTKWLIINSPSNPTGASYNFEELENIAKVLRKYSHVNVMSDDIYEHITFDDFKFYTLAQIAPDLKKRIFTVNGVSKAYSMTGWRIGYGAGSKTLIKAMTIIQSQSTSNPCSISQMAAIEALNGPQDYIKPNALNCQKKRDLALSILKRVKYFECYKPEGAFYLFVKCDKIFGHKTKSGTIIANSNDFAEYLLEEAKVAVVPGIAFGLEGYFRISYATSMEELEKACIRIEKTIDVIPA
What is the function of this protein?
Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate.  Can also transaminate prephenate in the presence of glutamate.
What are the official names of this protein?
Probable aspartate/prephenate aminotransferase, AspAT / PAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_PSEPG
Sequence: MTQISERLLVQAHLDAKQPNPLTAEQEAEYRAAIAAELKAQNAVLVAHYYCDPVIQALAEETGGCVSDSLEMARFGKNHPAETVIVAGVRFMGETAKILTPEKRVLMPTLEATCSLDLGCPVEEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCALEIVESLMDNGETIIWGPDQHLGRYIQKQTGADMLLWDGACIVHEEFKSRQLADMKALYPDAAILVHPESPEAVIELADAVGSTSQLIKAAQTLPNKTFIVATDRGIFYKMQQLCPDKEFVEAPTAGNGAACRSCAHCPWMAMNTLERVLDCLRKGGDEIFVDPALVPKAIKPLNRMLDFTQAARLKLSGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIB_ECOK1
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKPLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVATLEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCST_RALSO
Sequence: MTLQHTPLNAIHRSLGARMVDFGGWDMPVNYGSQIEEHHAVRRDAGIFDVSHMCVVDLTGARVRDFLRGLLANNIDKLQTPGKALYTCMLNPKGGVIDDLIVYFFREDWFRLVVNAGTAPTDIEWITAQNAAAGTGVAITPRRSDNNAGAEPLGIVAVQGPNARAKAYAALPGTQAVGEALKPFNAGFATIDGVGEIMVARTGYTGEDGFELVVPAAQIAGVWERLLQAGVRPCGLGARDTLRLEAGMNLYGQDMDEHVSPLDAGLAWTVDLQSERDFNGKAALAANGQRDQFVGLLLRDKGGVLRAHQKVITAAGDGEITSGTFSPSLSQSIALARLPKDVAIGADVQVEIRDRRLTATVVKLPFVRNGKALVS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: MHPC_PSESP
Sequence: MSAITEAGSSKFIDVTEGEINGSIHVNDAGNGDEVVVMFHGSGPGASGWSNFHRNVDAFVDAGYRVLLIDSPGFNKSYPIVTKSRDGAYAQAAKGVMDKLGIKRAHMIGNSMGGATAMRMAVDYPEMVGKLVMMGGGSVGGSTTTPMPTEGLKLLQGLYRNPSMENLRKMLDIFVYAPSTLTEELINGRFENMMRRPEHLTNFVESLKASGGRANYAHLLPTLTMPTMIIWGRDDRFVPLDLGLRMLWGMPDAELHVFSKCGHWAQWEHADKFNQLVLNFLAR
What is the function of this protein?
Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
What are the official names of this protein?
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MhpC family.
Protein: ROC5_ORYSJ
Sequence: MSFGGLFDGGGGGGMQFPFASGFASSPALSLALDNAGGGIGGRMLGGGAGAGSSAGGAMTRDTEAENDSRSGSDHLDAISAAGEDDVEDAEPSNSRKRKKRYHRHTPQQIQELEALFKECPHPDEKQRAELSRRLSLDARQVKFWFQNRRTQMKTQLERHENALLKQENDKLRAENMTIREAMRSPMCGSCGSPAMLGEVSLEEQHLRIENARLKDELNRVCALATKFLGKPISLLSPPPLLQPHLSLPMPNSSLELAIGGIGGLGSLGTLPGCMNEFAGGVSSPMGTVITPARATGAAIPSLVGNIDRSVFLELAISAMDELVKMAQMDDPLWVPALPGSPSKEVLNFEEYLHSFLPCIGMKPAGYVSEASRESGLVIIDNSLALVETLMDERRWSDMFSCMIAKATVLEEVSTGIAGSRNGALLLMKAELQVLSPLVPIREVTFLRFCKQLAEGAWAVVDVSIDGLVRDHNSGTAPTGGNVKCRRVPSGCVMQDTPNGYCKVTWVEHTEYDEASVHQLYRPLLRSGLAFGARRWLATLQRQCECLAILMSSATVTANDSTAISQEGKRSMLKLARRMTENFCAGVSASSAREWSKLDGATGSIGEDVRVMARKSVSEPGEPPGVVLSAATSVWVPVAPEKLFNFLRDEQLRAEWDILSNGGPMQEMTQIAKGQRDGNSVSLLRASAVSANQSSMLILQETCTDASGSIVVYAPVDIPAMQLVMNGGDSTYVALLPSGFAILPDGPRIGATGYETGGSLLTVAFQILVNNQPTAKLTVESVETVNNLISCTIKKIKTALQCDA
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein ROC5, GLABRA 2-like homeobox protein 5, HD-ZIP protein ROC5, Homeodomain transcription factor ROC5, Protein RICE OUTERMOST CELL-SPECIFIC 5.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYH7_HORSE
Sequence: MGDAELAVFGSAAPYLRKTEKERLEDQTRPFDLKKDVFVPDDKEEFVKAKIISREGGKITAETEHGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYAAWMIYTYSGLFCVTINPYKWLPVYTAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQTSGKGTLEDQIIEANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAKGALAKAVYERMFNWMVARINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSSNFQKPRNIKGKPEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVDLYKKSSLKMLSNLFANYLGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVIDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYRFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFARLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQHVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMKRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRDAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEVEQKRNAESIKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGLNEE
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction.  Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.
What are the official names of this protein?
Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain, cardiac muscle beta isoform, MyHC-beta.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere. Note=Thick filaments of the myofibrils.
Protein: RL23_DEHMB
Sequence: MNLYEVLRRPLISEKNSVHATQNKYAFEIAKGANKRMVKLAVEQAFNVTVEDVNMLHIPGKQKRMGRNLIQTAGLRKAIITLKEGDKITLFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL30_LACP3
Sequence: MAQLKITLTRSAAHRLPKQRKIVKELGLARVNSSVIKPDNAATRGAIFQISHLVSVEEIKD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SSTT_YERPS
Sequence: MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSIRPILFLYVLGTFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYAQLLVVLIGCMLLVALVVNPLIVYWKIRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGITVDLPTALLLSVVAAICACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDPLAAGKSV
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASSY_CALS8
Sequence: MQLNKVVLAYSGGLDTSVIIPWLKENFSCEVIAVVVDVGQEDDFETIKERAYKTGASKVYIEDAKAEFVKEYIFPTLKAGAVYEGKYLLGTSMARPLIAKRLVEIAKKENADAIAHGATGKGNDQVRFEVTIKALMPNIKIIAPWRMWNLKSREDELNYLAQKGIDIPFKKEESYSTDWNIWHLSHEGLELEDPWNMPNFEKVLMIIKNPFSLNDEPETIEIEFEKGVPIKINGKEMNCVELLKYLNKKGAEHGIGIVDIVENRLVGMKSRGVYETPGGTILHYAHRELEYLCLDRATLHFKEMVAIRFAELVYDGLWFSPLREALSAFVDKTQEVVNGTVKLVLYRGNIYSAGSKSPNSLYIKDLATFEEDQMYNQKDAEGFINLFGLPLKVFGMVNKKAGDSD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_METTH
Sequence: MIIGCSASQKLAASVADLLDEPLCPVETRKFPDGERYIRVKEEVEGEVTVVQSTGYPQDENLMELLFMIENLKDLGADYVRAAIPYFGYGRQERRFKSGEAVSAKIVAHLLEAAGADEIVTVNLHENCLSEFFRVPVRELSAMPLIAEHISFLDDPVIIAPDKGALGHAREVSDILGCECDYMEKVRISPEVVETRVSDLDVEGKDAVVVDDIISTGGTIVNAAGILGKCGASSITVCCVHPVLVEDALLKIFSAGVERVIATDTLKSDVSEISVAPLIADVMKD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_BRUC2
Sequence: MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKVPLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVLFASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIREKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA2_STAA1
Sequence: MGIIAGIIKFIKGLIEKFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 2 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: H12_HUMAN
Sequence: MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
What is the function of this protein?
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber.  Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.  Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
What are the official names of this protein?
Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Mainly localizes in euchromatin. Distribution goes in parallel with DNA concentration.
Protein: RL18_PSEA8
Sequence: MSVKKETRLRRARKARLKMRELETVRLCVYRSSQHIYAQVIAADGGKVLASASTLDKDLREGATGNIDAAKKVGQLVAERAKAAGVTQVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MOAC_PYRHO
Sequence: MVGGLTHVDEKGVKMVEIGYKDVVFRKAVAKGRIKLKPETVKLIKEGKIEKGNVLATAQIAGILAVKRTPELIPLCHPIPITGVDITFDFGEDYIEVTCEVRAYYKTGVEMEALTGVTVALLAIWDMVKAVEKDEKGQYPYTRIENVHVVEKVKTHNSQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Probable cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: LPLT_SHIFL
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILLAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASAIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAARPGQSWNLINMTRSFLNACTSLWCNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVPIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KUP2_RHILO
Sequence: MDLASRDSEAETVEQSSHSGAEQHSTKVLMLGALGVVYGDIGTSPIYAFREALHASPGIDTRAQVLGVLSLIVWALTIIVTIKYVAFVLRADNKGEGGTLSLMSLARTAYPKGARLILAIGLCGAALFFGDSIITPAISVLSAVEGLRVVTPTLDPYVVPITLLILAILFSVQRFGTGKVAAVFGPVTALWFLAIGVAGLYHLLDDPSILLAINPYYAVTYLASTPTAAFVTVGAVFLAVTGAEALYVDLGHFGRKPIVLAWFSVVFPCLLLNYFGQGAFVLANGGRPTNPFFQMLPDWALMPMVGLATAATVIASQAVISGAFSLTRQAVQLNLLPRIEVQHTSEMQLGQIYMPRINLLVALGVMLLVVGFGSSSSLASAYGISVTGEMLMTTILLFVVMRKLWKWRLAVALPLTLLFGIIDSGFFLANIVKIFEGGWVSITVACLMGLIMWTWIRGTRYLFDKTRRNEIPLDFLAANLLKKKPHLVPGTAVFLTSDPLSAPTALMHSLKHYKVLHEQNVILSVVTAPQPVVSDSDRVKMETVNDLFMRVTLTFGYMEQPNIPRALAICRKRGWKFDIMTTSFFLSRRSLKASPNSGMPVWQDRLFIGLARTAADATEYFQIPTGRVVEIGTQVAI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPE_ACIFI
Sequence: MAMTIDVRVVSAEGSIYAGVADMVVAPGEMGELGILPRHAPLLTGLRPGELRIIHGAETEYLFVNGGILEIQPDMVTVLADSAERATDIDEAKALAAKQAAEARMAGHTDQMEYAAAQAELLEQIARLKTVQRLREQGFVR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AGRG3_MOUSE
Sequence: MATARSLGLLFFLLLTSDEETTEEPRNVCRRLQEGHEYDTFDLNDTAQCFTKCGQSEHSPCDVGNLQRYWLNYESYLLENSMETVDMPFVKALIQNISTDVSEDLLYSLMLSQIPRQVMQGEDEPADGVRLPKSLFGALPGNRSAVRLAITVLDIGAGNVFKGPKLLEDKGSSVLNNRMVGLSVGQMHATGLSEPVEITFSHERQPPNVILTCVFWDMAKGDWDSHGCSTVPGDGRTVCRCDHLTFFALLLRPILDLATAQTLTRISQAGSAVSMIFLAFTMVLYVAFRFSLQRFKSEDAPKIHMALSISLFLLNLTFLINVGSSSQGPPASCWVRAAIFHYFLLCVFTWMGLEAFHLYLLAIRVFNTYFGHYFLKLSLLAWGLPVLVVIGAGSSNSYGVYTIRDQENRTSLELCWFQKEPALYATVHGYFLVTFLFGAVVLALVAWKIFTLPSVTAGKGQGPTWKSVLTVLGLSSLVGMTWGLAVLTPLGLSTIYVFTLLNSLQGLFIFCWFIILYFPTQSTTASSSGTARLDQAHSVSQE
What is the function of this protein?
Orphan receptor that regulates migration of lymphatic endothelial cells via the small GTPases RhoA and CDC42 (By similarity).  Regulates B-cell development (PubMed:24113187).  Seems to signal through G-alpha(q)-proteins (By similarity).
What are the official names of this protein?
Adhesion G protein-coupled receptor G3, G-protein coupled receptor 97.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: ACT26_DICDI
Sequence: MEDNITSIVIDCGSGMCKAGIGGEEFPRVSFPSIVGKPRFEKTMCAIGNKEYYVGDEAQSQRGMLSLKYPIKNGIVVNWEYMEKLLFHMFYNELRVSPDQYPILFTESPLNPKSNREMLTQIMFEKFNVPALYIAIQAVLSLYASGRTCGIVLDSGDDVTHTVPIYGGYVLQHSIIRLNFAGSDLTEYMAKLLLERGYSFTTTSEMEIVKSIKEKLAYVAINFNAEMSKPIDTLETTYQLPDGQIIIIGNERFRCAEALFQPSMIGLECDGIHETIFKSIMMCDIDIRKHMYANILLSGGNTMLSGISDRIYNQLRELAPNNMKILIVASPERKNLVWIGGSILTTLPLFQEMWISKEEYDEHGPSIINKKVGLY
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction (By similarity).
What are the official names of this protein?
Putative actin-26.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.