PharMolix/UniProtQA huggingface dataset:
Protein: KASB_MYCTO
Sequence: MTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGSPEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDPEIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the elongation of long chain acyl-ACP substrates by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Involved in extension of the mycolate chains to full lengths and produces longer chain multiunsaturated hydrocarbons averaging 54 carbons in length.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 2, Beta-ketoacyl-ACP synthase 2, KAS 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_MESH7
Sequence: MKKHAKVYYSENLVEQVNEFETSFEIKPLERGLGNTLGNALRRTVLSSIPSCAVFGVKIEGIKHEFTVLDDVIEDVVTILNNLKRVRFFYNPSVFSQNSIHVASFLGQKAGQIYARDIESHSGLKIVNPDLYIADVSKVGALKFELFITNGKGFVDFETNKKYVNEVISRLESQIEGSVLAVDSDFSPVLNANYQAVEINSASPIIEEKLNFSIKTDGSIFAKDALSQGAKILIAHLNLLADVENLNKFSADFFGDQEIKEEPIRRFSNSIDALDLSVRSLNALRRAQYYKISDIEKLSQDDFENIKNLGRKSVQEIMEKLQNYKNENKGEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: OBG_SALSV
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRDLLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDSEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGSDPVENARIIIGELEKYSQDLAAKPRWLVFNKIDLMDKTEAEEKAKAIAEALGWEGKYYLISAASQLGVKDLCWDVMTFIIENPIAQAEEAKQPEKVEFMWDDYHRQQLAEVEEDADDDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMRL1_DICDI
Sequence: MSKKVLVFGGTGYQGGSVVRELLKDDSFKVITLSRNPESEKCKELKKLGADVIKCDESQPKEEIEKVMKGCDCVYLVTNSQGYCEKEIEYGIKVADVALKCGVKHFIFSTVPGPNKLSNGKFKSPDLDNKVEIEQHIRQLSKSNPEFISSFVIAPWYFQNFINYYQPEKESSTSDKYILKWACDPKVSLDYGDIDELGLLVREIFKNPIKFSGETVPFSSEILTPIQIVEIISKVTNKKVSYQFIDPVEYGKSYDLEVSLMLAFFNEYGGFNIYGGDRSIAHNIKKLTSFEEYLKKINYKLD
What is the function of this protein?
May be a redox sensor protein.
What are the official names of this protein?
NmrA-like family domain-containing protein DDB_G0286605.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: NUOB_SALG2
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL3_SALSV
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL11_METKA
Sequence: MPKEEVEVLIEGGKADPGPPLGPALGPLGVNIQEVVEEINRKTKDFKGMEVPVKIIVDTETREFEVKVGSPPTSAIIKSELGIDKGAHEPRHETVGDLSMEQVIKIAKMKFDDLLSYDLKTAAKEILGTCGSMGVTVEGKDPKEVQKEIDEGKWDDLFEKYEEEEE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MEPA_KLEP7
Sequence: MKNTVIALLALLASAGSLAATPWQKITQPIGGSAQSIGAFSNGCIVGAEALPLSAPGYQVMRTDQRRYFGHPDLVQFIQRLSNQVHNKGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPQTRWTSSQLLKPQALDLVASDGKHVVPSLWSPQISQLIKLAAEDSEVTRIFVNPAIKQQLCLDAGSDRQWLRKVRPWFQHRAHMHVRLRCPAGSLECEDQAPPPPGDGCGAELQSWFEPPKPGSTPPVKKTPPPLPPSCQALLDEHVL
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VATB1_GOSHI
Sequence: MGMAENTNGMEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGTTRRGQVLEVDGEKAVVQVFEGTSGIDNKYTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTGDLLEDGEEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHADVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKVVTQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTHDQYYSRDAGN
What is the function of this protein?
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit B 1, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: NFUA_VIBCM
Sequence: MSNPITITESAQSHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAVEATDTEYPFSGFSAYVDELSLPFLEEAVIDFVTDKMGSQLTLKAPNAKMRKVSDDASLMERVEYALQTQVNPQLAGHGGHVRLISISDDGVALVQFGGGCNGCSMVDVTLKEGIEKELLAQFAGELTAVRDSTEHDRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: Y173_UREPA
Sequence: MRTGKYITKYDYIGYYTKQKAMWFFTNAEIKAKIDLLLKNVSSYDFEDLDDEEEHDYEIDAYEIYKEQTDFLSQLEINKNIDVDNPKIAEGILLDKASQEDIKKTYHYIKKIINFETDPLFKNKSLEELANLTLELIDKNDKIIFFQPVFINDKLITKPDCFIKKNDEFIVIETKGTSSIKKHHILDVFYQAQVISKHPYFINKCISYQMCIVDYVKLKKNQVNFTISPYYNYQKSVVLSLPPSAANQFNKFEINELKRKRKRGEAIYLKKDENKKYYEDIDAYDHCKGILIDDLIDGTYSSINDYKEAKKIYDYKTEDLKDDVRFNKTMDELIKGIEKLHNDFDEVISELLVHKQNLLALPIEQRIPNYFIPSYNDKGDYKDNDFWLELRNLYAYSGYDVIKYSGKILTIKKFGLDNVTKDILGIDILKTYANQTFFNLYKNNQIKIYQAAVDLFAKLKSKKVYFDFESINSAIRAVDNSFPFTQTVTQNSIIIDDGSCDIKNLKCTNMIIDPREINNEWFKAIIDKIHQGLEYSYIVYNKSFEASRLKEMAEFINEEIYELKVSEIIKNMYDLADFFIVSMGKQLIVIPELKGFYSIKKVLPIIEKEFPQIYHDVNCLNYKELSVGNGLVCQTKTTKRFFNTITDLEWEQFVHDARIYCENDVRAMIAVEYFIKKLIDEAKMKNLILS
What are the official names of this protein?
Uncharacterized protein UU173.
What is the protein family that this protein belongs to?
To M.genitalium MG366 and M.pneumoniae MPN544.
Protein: PSD_BACAC
Sequence: MRRTLYRLMIELTNGRFTSYTLRKFAQSRLSSIIIPSYAKVFQINQDEMEKGLKEYRTLHELFTRKLKEGKRSIDTDASSIVSPVDGVFADHGPIEDTKTFDIKGKRYSIVDMLGNEERAQRYAGGTYMVIYLSPSHYHRIHSPLSGSVTERFVLGRKSYPVNAAGMEYGKEPLSKNYRSVTEVNSDGEHMALVKVGAMFVNSIELLHERDTVQKGEEMAYFTFGSTVVLLFEKDMIEVVQELKSGQELRLGEKIATRLAHK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KDSA_RHILO
Sequence: MAPNSSVTVGNVVFDNNAALALIAGPCQFESRQHAFDMAGALKELTARLGIGLVYKTSYDKANRTSLSATRGAGMDAALPVFDELRKEFSLPVLTDVHTEEQCAIVAPHVDVLQIPAFLSRQTDMLVAAAKTGKVINVKKGQFLAPWDMKNVVAKITGSGNPNVLTTERGASFGYNTLVSDMRALPVMAEIGAPVIFDATHSVQQPGGQGGSSGGERRFVETLARAAVAVGVAGVFIETHQDPDNSTSSDGPNMLPLKDMPALLERLMAFDRIAKGR
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_OCEIH
Sequence: MANRFAVILAAGQGTRMKSKLHKMLHPVAGRPMVQHVVDQLQQVNLNKIVTIVGFGAEKVKAQLGSSSEFAFQKEQLGTGHAVLQAEDLLKDEKGVTVVACGDTPLIRAETFEELIQYHKKTGAKASILTTKVENPTGYGRVVRNDQDEVERIVEHKDANEGERLIQEINTGTYCFDNQALFAALKEVSNDNAQGEYYLPDVIKILRHQGDTVSAFMTPDFDETIGINDRIALAEAEKIMKKRINEQHMRNGVSIIDPEQTYIEPDVQIESDVILHPGTVLKGETIIRTGAEIGPHSELKDCEVGEDTVIRHSVATSSKVGNRVNIGPYAHIRPESRVGNDTKVGNFVEIKKTNLGDHSKVSHLSYIGDADVGERVNVGCGTITVNYDGTNKYLTTIEDDAFIGCNSNLIAPVTVGKGSYVAAGSTITKNVPENALSIARARQTNKEEYASKFKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_SYNP6
Sequence: MSKRTLASLTAADLEGKRVLVRVDFNVPLDGNGKITDDTRIRAALPTIRYLSESGAKVILVSHFGRPKGKPVESMRLTPVAERLSELLGRPVVKTTDAVGAGAEAQVAATSNGQVVLLENVRFHAEEEANDAEFAKALASLADIYVNDAFGAAHRAHAPTAGVTEYLSPCVAGYLLEKELQYLQAAIDNPQRPLAAIVGGSKVSSKIGVIETLLDKCDKLLIGGGMIFTFYKAQGLSVGGSLVEEDKLDLARSLMAKAQEKGVQLLLPVDVVVADKFAPDANAKTVAIDAIPDGWMGLDIGPESVKQFEGALADCRSVIWNGPMGVFEFDQFAVGTEAIARSLAGLTRKGATTIIGGGDSVAAVEKVGVASEMSHISTGGGASLELLEGKVLPGVAALDDAA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHA5_HUMAN
Sequence: MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTLPKLLCMRSHVDRYFTQKEETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RL33_RICAH
Sequence: MAKKNKNVLVRLVSTAGTGVFWVKKRNPKTQTEKLSFRKYDKVVRKHVLFKEEKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HEMH_RALPJ
Sequence: MPFLPEPLFQHGQPDRTAILLVNLGTPDGTSPREVGRYLRQFLSDPRVVEIPRAVWWFILNVLIVPLRSRASAHKYESIWLREANMTGSPLLVYSERQAHALQQLLNAQGHDVVVACAMRYGNPSIPSVMQALRKQGVERILVLPMYPQYSGTTTATAFDEVFRVLGEMRNQPELRLVKHFHDDPAYINALHQQVGAYWAQHGAPDFAHGDKLVLSFHGVPRRTLELGDPYHCECLKTGRLLGEALGLQPGQYLVTFQSRFGRAEWLQPYTAPTLEELGRVGTNRVDVFCPGFPADCLETLEEIAMEGQSTFRVAGGKEFHYIPCLNDSEAWIAGIADIALAHLQGWPLTLTHPHVLEASRTRAQSKGAAA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBGA_MYCGE
Sequence: MDTYTSAKINWFPGHMKKIHDQLKKLSSQIDGIIEIVDARAPTLTHNSEIISYFLNKPKLILALKTDLAQYKPNKKILFGSLKEPFKLKKKVLKTLTTLFANKRQQLKAKGLLIKQFRLAVIGMPNVGKSSLINLLINKNHLKVANRAGITKSLNWIQISPELLLSDTPGVFLKRIDEIQIGYKLVLTNVIRREVVNIEEVGMFAFNYLKKHYKQLLPFEADSFINFLEKFAKVRGLIKKANELNTNLACEIFINELINGKYGKLSYELN
What is the function of this protein?
Required for a late step of 50S ribosomal subunit assembly.  Has GTPase activity.  Binds to the 23S rRNA (By similarity).
What are the official names of this protein?
Probable ribosome biogenesis GTPase A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TA2R1_PANTR
Sequence: MLESHLIIYFLLAVIQFLLGIFTNGIIVVVNGIDLIKHRKMAPLDLLLSCLAVSRIFLQLFIFYVNVIVIFFIEFIMCSANCAILLFVNELELWLATWLGVFYCAKVASVRHPLFIWLKMRISKLVPWMILGSLLYVSMICVFHSKYAGFMVPHFLRNFFSQNATIQKEDTLAIQIFSFVAEFSVPLLIFLVAVLLLIFSLGRHTRQMRNTVAGSRVPGRGAPISALLSILSFLILYFSHCMIKVFLSSLKFHVRRFIFLFFILVIGIYPSGHSLILILGNPKLKQNAKKFLLHSKCCQ
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 1, T2R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRVP2_NAJAT
Sequence: MIAFIVLLSLAAVLQQSSGTVDFASESSNKRENQKQIVDKHNALRRSVRPTARNMLQMEWNSNAAQNAKRWADRCSFAHSPPHLRTVGKIGCGENLFMSSQPYAWSRVIQSWYDENKKFVYGVGANPPGSVIGHYTQIVWYNSHLLGCGAAKCSSSKYLYVCQYCPTGNIIGSIATPYKSGPPCGDCPSACVNGLCTNPCKHHNVFSNCQSLAKQNACQTEWMKSKCAASCFCRTEII
What is the function of this protein?
Inhibits carbachol-induced muscle contraction and weakly blocks muscle contraction evoked by potassium.
What are the official names of this protein?
Cysteine-rich venom protein natrin-2, Cysteine-rich venom protein 2, NA-CRVP2, Protein G2b.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35A_XENLA
Sequence: MSGRLWCKATFAGYKRGLRNQREHTALLKIEGVYARDETEFYFGKRCAYVYKAKNNTVTPGGKPNRTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L35a, L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_BURO1
Sequence: MKVVAFERQQQGTGASRRLRNAGKTTGIVYGGEAAPQKIELDHNALWHALKKEAFHSSILDLEVAGQSQQVLLRDVQYHPFKQLVLHVDFQRVDAKKKLHTKAPLHFLNAEVSPAVKLSSAIVSHVATEIEIECLPADLPEFLEVDLSKIEAGQSLHAKDIALPKGVALVAHVDAENPVIASATVPAGAVSDAAEGETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: FABP_ANOGA
Sequence: MAVWEGKKYKMEKSEGFDDYMKALGVGMVLRKLGNSISPTVELVKNGDEYTFNTLSPSRTRRSSSSWAMEFDEETVDGRMVKSVCTFDGNKLIHEQKGEKRPRSCASSLPPI
What are the official names of this protein?
Probable fatty acid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: RRP40_SCHPO
Sequence: MAEVEEKGLLSYYFPGERIPDSIISQDGSIRLGPGLVFQKKDREEEIVVSKAGRLHQTGKNAMLIDSRTKRYIPATNDQVIGQIISRFAEGYRVDIGSAHIAQLNALAFENVTRKSRPNLNVGSLVYARVSLADRDMEPELECFDATTGKAAGYGELKNGYMITGLSLSHCRKLILPKNTLLQTLGSYIPFEIAVGMNGRVWVNSENLSTTVLICTAIRNCEFMSDEEQIKYCKDLIKKL
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  rrp40 as peripheral part of the Exo-9 complex is thought to stabilize the hexameric ring of RNase PH-domain subunits (By similarity).
What are the official names of this protein?
Exosome complex component rrp40, Ribosomal RNA-processing protein 40.
What is the protein family that this protein belongs to?
Belongs to the RRP40 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: NORM_BACAN
Sequence: MKETNSFSQKLKQFVLLFFPIFVTQMSLFAMSFFDTTMSGHASPIDLAGVAIGTSIWIPVSTGLTGILMATTPIVAQLVGSKKKEDVPHVIIQAVYLAICASFVVILIGLFTVTPILNGMRLEEPVERIAAQFLSIIAIGIIPLFTYTVLRGFIDALGKTRTTMIITLLSLPINVVLNYVLIFGNFGFPKLGGVGAAIASAATYWCILIITVMIIRTKEPFASFNIFKQLYRPSLSSWKEFLKLGVPIGFAIFFETSIFAAVTLMMSNFSTTTIAAHQAAMNFASLLYMTPLSLAMAMTIAVGFEVGAKRYNNAKQYGFIGIGLALAFALLYSILLYFFDDEIASIYTTDIQVHHLAKEFLIFAILFQISDAIATPVQGALRGYKDVNVALIMTLIAYWVIGLPLGYILATYTDWAAKGYWIGLIIGLAFGATFLLIRLFQVQRKYTTQNSRS
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2240_MANSM
Sequence: MEMTSTQRLILANQYKLMGLLDPANAQKYARLETIVKGGFSLELKELDNEFLAISEAECQTVLETLEMYHALQVSYENLADKSDLTAHRLQFIGYDAIRERKYLNYLRFITGIEGKYQEFMRCAPGCDSQTPMWDKYNKMLDMWKACPHQYHLSLVEIQNILNA
What are the official names of this protein?
UPF0304 protein MS2240.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: HIS4_AZOSB
Sequence: MLLIPAIDLKDGQCVRLKQGEMDDATVFSEDPAAMARHWIKQGARRLHLVDLNGAFAGKPKNGGAIRAITDEVGDDIPVQLGGGIRDLDTIEHYLDNGISYVIIGTAAVKNPGFLHDACGAFPGHIIVGLDAKDGKVAVDGWSKMTGHDVVDLAKKFEDYGVEAVIYTDIGRDGMLSGVNIEATVRLARALRIPVIASGGIASLTDIEALCAVEDEGIMGAITGRAIYEGTLDLSAAQSRADALRAPGGAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_BARVE
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPKAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMALTIPQARQLVNHGHILVNGRIVDIPSYRCKPRDIITVKDEQNSRTLVQNLLDSSAPEELPNHLTLHTFQYEGLVNQIIDRKCVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DTD_PARUW
Sequence: MKLVIQRVLQAQVYIDDNLFSAIGPGLMLLLGIHHQDNLEQILWSVDKLVHLRIFNDENGKMNRNVKECEGEILVVSQFTLYGNCLNGRRPDFIQAASPPIALSLYRQFIDELKKEAPHVKTGQFGAQMQVSLTNDGPVTFILESLDRRKA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.