PharMolix/UniProtQA huggingface dataset:
Protein: RS11_BARQU
Sequence: MAKQATRVRRRERKNILSGVVHINSTFNNTMVTITDAQGNAIAWSSAGAQGFKGSRKSTPFAAQVAAEDCARKAQEHGMRSLEVEVCGPGAGRESALRALQSAGFVITSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS9_RHOCS
Sequence: MAQTITSLADLKQGPGAEPAGLSAEPQEPKLDKEGRAYATGKRKDAVARVWIKPGSGKIIVNGRDLGVYFARPVLRMMINQPFSIVARVDQYDVMCTVSGGGLSGQAGALRHGISKALTYYEPALRPALKAAGLLTRDPRVVERKKYGRAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DAPB_BURCH
Sequence: MKIAIAGASGRMGRMLIEAVLNDADAQLVGALDRAGSPFLGQDAGAFLGKDTGVKLTDDLDAVFAQAEYLIDFTRPEGTMAHIEAALRHDVKLVIGTTGFTAEQKADLQAAAARIGIVFAANMSVGVNVTLKLLEFAAQHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLDDCAVYGRHGVTGERDPSSIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVRFLSARGAGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_ORITB
Sequence: MATKKAGGSSKNGRDSAGRRLGLKKTDGQLVNAGNIIVKQRGTKFYPGKNVGLGKDHTIFSLVSGKVKFFRKKKNRVFISVVVDDSTAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: G3P_BRUMA
Sequence: MSKPKVGINGFGRIGRLVLRAAVEKDTVDVVAVNDPFINIDYMVYMFKYDSTHGRFKGSVSAEGGKLIVTNGKTTHHISVHNSKDPAEIPWGVDGAEYVVESTGVFTTTDKASAHLKGGAKKVIISAPSADAPMFVMGVNNDMYDKANNHIISNASCTTNCLAPLAKVIHDKFGIIEGLMTTVHATTATQKTVDGPSGKLWRDGRGAGQNIIPASTGAAKAVGKVIPGLNGKLTGMANRVPTPDVSVVDLTCRLQKGATMDEIKAAVKEAANGPMKGILEYTEDQVVSTDFTGDTHSSIFDSLACISLNPNFVKLIAWYDNEYGYSNRVVDLISYIASR
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_JANMA
Sequence: MLEFNNSTPLTMGVELELQIVNRRDYNLTRGSSDLLVIIDKTDHGYDIKPEITESMIEIATSVHTDHKEMLAELTAMRTLLISAADKLNLGLAGGGAHPFQHWEDQRIYPTDRYRLVSELYGYLAKQFTVYGQHIHIGCATGDEAIRLAHMLARYIPHFITMSASSPFYQGVDTTFQSSRLTSINAFPLSGYMPFVTDWDSFNAYFDKMSSLGIVASMKDFYWDIRPKPEYGTVEIRVCDTPLSIEVAVALAGYAQTLSKFFFAQQELKPAQDTYLTYSYNRFQACRFGLNGALINPINGTQTSIKEDILQTFEMLADIAQELGTTEAIELLRQRIQAGQSDADWLRASYEKSGSLSDVVRQQSAVWMAR
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: UTP4_YEAST
Sequence: MSSSLLSVLKEKSRSLKIRNKPVKMTSQERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEIWNPRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVLIDISGGPGVLEHDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRIWSAQKNDENMGRLLHTMKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRKIFQFSQNTNKSQKNNRWVNSSNRLLHGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTSFSNGNYRKMPTVEPYSKNVLVNKEQRLVVSWSESTVKIWTMGTDSSTEQNYKLVCKLTLKDDQNISTCSLSPDGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDNDLLLRTSTKLVKFIDNSKIVICSCEDDVFIVDLESEEDEKPQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVISRGCGVVDILDLKARISKPLARLNNFITAVHINTSRKSVVVITADNKIYEFNMNLNSEAENEDSESVLTQWSKNNTDNLPKEWKTLKENCVGIFSDIENSSRLWFWGATWISRIDFDVDFPINKRRKQKKRTHEGLTITDESNFMNDEEDDEDDDIDMEISENLNVLLNQGNKIKSTDVQRNEESSGHFFFTDKYKPLLFVDLISSNELAIIERNPLTFHSKQKAFIQPKLVF
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 4, U3 snoRNA-associated protein 4, U three protein 4, U3 protein 4 required for transcription, t-UTP4.
Protein: ATPF_NEIG1
Sequence: MNINATLFAQIIVFFGLVWFTMKFVWPPIAKALDERAAKIAEGLAAAERGKSDFEQAEKKVAELLAEGRNQVSEMVANAEKRAAKIVEEAKEQASSEAARIAAQAKADVEQELFRARESLRDQVAVLAVKGAESILRSEVDASKHAKLLDTLKQEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RBFA_PARMW
Sequence: MAQGRRVERVAALIRKETSELLINGIRDERVHQGMVSITNVEVSGDLQHCKIFVSIFGDEASQLQVMEGLQAASGYLKGELGRRLQMRRAPDVVFQLDRGIERGTSVLGLLNKLEDERKERGEIPAGSDELPAE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_DEHMC
Sequence: MLQPKRVKFRKVQRGRRDGAAHKGNTVAFGEFALQSLEAGWITARQIEATRRAITRYIRRGGQVWIRIFPDKPITKKPAETRQGGGKGAPEEWVAVVRRGRIMFEIGGVTPEAAKEAMRLASYKMPVKTRFVARDIPVVAGETEVEEAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DEF_PECCP
Sequence: MAVLQVLHFPDERLRITAQPVKEVNADIQRIVDDMFDTMYEEEGIGLAATQVDIHQRIIVIDVSEERDQRLVLINPELIEKSGDTGIEEGCLSIPETRALVPRAEHVKVRALDREGKTFELEASELLAICIQHEMDHLVGKLFIDYLSPLKRQRIRQKLEKLAKQNSRAR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ANMK_BURCJ
Sequence: MPQRQPQPAHPADGIYFGLMSGTSMDGVDGVAVRFEAGRAPVVLAEAFVGFAQSLRDALFALQQPGDNEIDRESLAANALVTRYAVCCHELQRTAGLSRDEIRAIGVHGQTVRHRPERGYTRQLNNPALLAELTQVDVIADFRSRDVAAGGHGAPLAPAFHATVFGAPGETRVVCNLGGISNITILPGAGGDVRGFDCGPANALIDAWATRHLGKPYDDGGKFAARGTVHAALLAALLDEPYFTAPPPKSTGRDLFNPAWLDAKLAAFSQVAPEDVQATLTALTAVSVAREVAQHAPGCKAVFVCGGGARNPVLLDALRHALREAGVPATVDTTAALGVPPQQVEALAFAWLAYRFTARQPGNLATVTGAAGNRVLGALYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DAPF_LEPBL
Sequence: MAALKFTKMEGIGNDYIYIDSTQANIRLTPEQIQKISNRNFGIGSDGVIFIRNSKQGDFMMDMYNSDGSSSEMCGNGIRCVAKYIYDHGLTNSKNPKIETGAGVLEVDLKIGSGNKVDFVSVNMGKPILVPSKIPVNWKDEEAIIDQTFEIAGKNLKFTAVSMGNPHCVIFVDDCDQFPVTGIGPLIERHPIFPKRINVEFVTVRGKDHFYQRTWERGAGETLACGTGACAVTVAGNLTGKSGKEVKIDLRGGTLRIQWQESGNVLMTGPAKEIFSGEIEV
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_META3
Sequence: MEKTMLEQKLENTILPLLLKKELINKIISEKIEDENIIRDIISETVKSYERTLVEPNESVGVVAAQSLGEPGTQMTMRTFHYAGVAELNVTLGLPRMIEIVDARKEPSTPTMTVYLTEDYAFDKSKAEEVAKNIESITVQNIAQDIHIDMVKLAINVVLNPESMKQRNITADDVMEAIKKKMKLKIEQEGNILRLIIKTPSLKALRKRIPKVKSIHLKGVPNIPRVIVKKDDTMGEYILHSEGSNLSAVFEIDGVDMVRTTSNNIVEIQDVLGIEAARNAIINEISGVLNQQGLNVDIRHLMVIADIMTADGSVKSIGRHGLSGEKASVLARAAFEETVKHLYSAAEKGHSDKLSGVVENIIVGKPISMGTGCVDVYIDRDYEEGKDLMITVEKEEN
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_APIGR
Sequence: VGFKAGXKDYKLTXXTPEYETKDTDILAAFRXSPQPGVPPEEAGAAVAAXSSTGTWTTVWTDGXTSLXRYKGRCYGIEPVVGEENXXIXYVXYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAXNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARIEGRDLASEGNEIIREATKWSPELAAACEVWKEIKFEF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2320_MYCBO
Sequence: MKYLDVDGIGQVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEALGDDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQSRDALTDAARAFRPVSTGRFLTDMVREKVSRR
What are the official names of this protein?
Uncharacterized oxidoreductase Mb2320.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: GCH1_PELTS
Sequence: MFDQHKIEKAVRLILEAIGENPEREGLKGTPARVARMYEEIFSGLQEDPEEHLQKIFSEEHEEMVIVKDIPLYSICEHHLLPFYGKAHVAYIPRKGKVTGLSKLARVVEGFAKRPQLQERLTSQIADTIMRRLNPIGVLVVIEAEHMCMTFRGVKKPGSKTVTSAVRGLFRKNVATRAEAFSLIKGQA
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GLYCO_RABVC
Sequence: MVPQVLLFVPLLGFSLCFGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSEFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVRTTKESLIIISPSVTDLDPYDKSLHSRVFPGGKCSGITVSSTYCSTNHDYTIWMPENPRPRTPCDIFTNSRGKRASKGNKTCGFVDERGLYKSLKGACRLKLCGVLGLRLMDGTWVAMQTSDETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLKVGGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLKSSVIPLMHPLADPSTVFKEGDEAEDFVEVHLPDVYKQISGVDLGLPNWGKYVLMTAGAMIGLVLIFSLMTWCRRANRPESKQRSFGGTGRNVSVTSQSGKVIPSWESYKSGGEIRL
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: GSA_HELPY
Sequence: MELLHSINDFNEAKQVIAGGVNSPVRAFKSVKGTPPFILKGKGAYLYDVDNNHYIDFVQSWGPLIFGHADEEIEENIINALKKGTSFGAPTELETTLAKEIISCYEGLDKVRLVSSGTEATMSAIRLARAYSQKDDLIKFEGCYHGHSDSLLVKAGSGCATFGSPSSLGVPNDFSKHTLVARYNDLNSTEECFKKGNVGCVIIEPIAGNMGLVPAQKEFLLGLKALCEKYQAVLILDEVMSGFRASLSGSQEFYGVVPDLVTFGKVIGAGLPLACFGGRAEIMDLLSPIGSVYQAGTLSGNPLAVCAGLSALYKIKRDKTLYTRLDALAIRLTQGLQKSAQNYNIALETLNMGSMFGFFFNENAVHDFDDALKSDTEMFAKFHQKMLFKGVYLACSSFETGFICEPMTEEMIDLTIAKADESFDEIIKGV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIT1_RAT
Sequence: MSRENNCTTADLAWGIPSITQAWGLWALFGVVTMLLLISLAALLSQWTRGRRRTQEEQGPPSGRSVEEVPLYGNLHYLQTGRLSEESRSEEQDPSSGGLARGAEEATCYTSLQLRPAQGRIPSSGTPIKYCEVVLDSEPKPQASGPEPELYASVCAQTRRARASFPDQAYANSQPAPS
What is the function of this protein?
Negatively regulates T-cell antigen receptor (TCR)-mediated signaling.  Involved in positive selection of T-cells.
What are the official names of this protein?
Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein.
Protein: IF4G2_WHEAT
Sequence: MTTDQPVISLRPGGGGGGPRGGRLFAPAFAVAASGSGDFLRPHGGGAFRALQDWCLHLSHERVRYSRDQLLDLRKITDVTEQILRLQQEIEAELHGDDQSWVRNDSNVQLQTQTQTQVQAQNRFTETDNRDWRARTEKPPAPAVPEEKSWDNIREVKEQYNASGRQQEQFNRQDQSSSQKAQVGPPPALIKADVPWSARRGNLSEKDRVLKTVKGILNKLTPEKFDLLKGELLDSGITTADILKDVISLIFEKAVFEPTFCPMYAQLCSELNDNLPKFPSEEPGGKEITFKRVLLNNCQEAFEGADSLRVEIASLTGPDQEMEKRDKERIFKLRTLGNIRLIGELLKQKMVPEKIVHHIVKELLGSDKKACPDEEHVEAICQFFNTIGKQLDENPKSRRINDTYFVHLRELVANPQLTPRSKFMVRDLIDLRSNNWVPRRAEIKAKTISEIHTEAEKNLGLRPGATANMRNGRNAPGGPLSPGGFSVNRPGTGGMMPGMPGSRKMPGMPGLDNDNWEVQRSRSMPRGDPLRNQGSLINKVSSINKPSPINPRLLPQGTGALIGKSALLGTGGPPSRPSSITASPTPLPAQTTASPKPSSATPASVPIPDKAASSAKVIPAGLEKKTASLLEEYFGIRILDEAQQCIEELQSPDYHPEIVKEAINLALDKGASFVDPLVKLLEHLYTKKTFKTEDLENGCLLYGSLLEDIGIDLPKAPTQFGEVIARLILSCGLRFEAVEGILKAMEDTFFRKAIFTSVTKTLEADPAGQAILSSHAAVVDACNSLSI
What are the official names of this protein?
Eukaryotic translation initiation factor isoform 4G-2, eIF(iso)-4G-2, eIF(iso)4G-2, Eukaryotic initiation factor iso-4F subunit p82-16, eIF-(iso)4F p82-16 subunit.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: TPM2_HUMAN
Sequence: MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.  The non-muscle isoform may have a role in agonist-mediated receptor internalization.
What are the official names of this protein?
Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: TXPT6_MACGS
Sequence: TSQGTTPDKVQLEVNCISNLPNNEVEETDLLRELEMIEENLFGKELSFVPEENRNSRHKRCMGYDIECNERLHCCADLECVKTSGRWWYKKTYCRRKSG
What is the function of this protein?
Inhibits voltage-gated sodium channels by binding to site 3.  Insecticidal neurotoxin (By similarity).
What are the official names of this protein?
Mu-hexatoxin-Mg1c, Mu-HXTX-Mg1c, Peptide toxin 6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 09 (magi-1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1713_SODGM
Sequence: MEIWVDADACPRVIKEILFRAAVRHEIQTTLVANQSLPVPPSRFIRTLRVAAGFDVVDNEIVKRAAAGDLVITADIPLAAEVLAKGALALNPRGELYQQATIREKLTLRDFMDTLRGSGIQTDGPPPLGQRERQEFARQLDKWLHQVQARR
What are the official names of this protein?
UPF0178 protein SG1713.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RL19E_ARCFU
Sequence: MMVMDLSLQRRLAASVLKCGENRVWFDPAALEDIATAATKQDIRELIEQGVIKRKPVNGVSRARINKRKLQKRKGRRRGHGSRKGAKGARMPRKRMWILRIRALRKALRQMKAEGVVDRRTYRILYRKAKGGEFRSVAHLKIYVEQMKR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: RSMG_BURCH
Sequence: MTARRAPAVNRDVLEGMLVEGTAALDLTLTDTQRNQLLDYVALLGKWNAVYNLTAIRDPMQMLIQHILDSLSIVPHLRGRTSARVLDVGSGGGLPGIVLAIVEPGWQVTLNDIVQKKSAFQTQMRAELKLANLSVVTGRVESLQPGVEVPEKFDMIVSRAFADLSDFVKLARHLVAPGGSIWAMKGVHPDDEIARLPEGSRVTQTIRLAVPMLDAERHLFEVAVDDAN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I77AB
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKKQLKKDLKSQEQCAGSPTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: LEU1_SHEFN
Sequence: MSNRVIIFDTTLRDGEQALAASLTVKEKLQIALALERLGVDVMEVGFPVSSPGDFKSVQTIAKTIKNSRVCALSRALEKDIDAAAQALSVADQFRIHTFISTSTIHVESKLKRSFDDVLEMAVNAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEEAIKAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDQAVISVHCHDDLGLSVANSIAAVEMGARQVECTINGIGERAGNCSLEEIAMILATRKGLLDLDCGINAKEIHRTSSLVSQLCNMPIQANKAIVGTNAFSHSSGIHQDGMLKAKNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMEEMGYKPTDYDMDSLYEQFLTLADKKGQVFDYDLEALVFMESQAQDDDKYQLQHMMVHSDSTEGVATATVRIAVDGKDITEAATGNGPVDAAYNAIARATDRKINITNYKLSAKGEGQNALGQVDITAKYNEQMFHGVGLATDVVEASAQALVHVMNLVYRADKVADFKQQIHKERELGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SNMP1_OSTFU
Sequence: MQLQKPLKIGLGMMGAGLFGIIFGWVLFPVILKSQLKKEMALSKKTDVRAMWEKIPFALDFKVYMFNYTNVEEIMKGAAPIVKEIGPFHFDEWKEKVDIEDHDEDDTITYKKRDYFYFRPDKSGPGLTGEEVVVMPHLLMLSMATIVNNEKPAMLNMLGKAFNGIFDEPKDIFIRVKVLDLLFRGIIINCARTEFAPKAVCTALKKEGATGMTFEPNNQFRFSLFGMRNGTIDPHVVTVRRGIKNVMDVGKVIAIDGKTEQDVWRDKCNEFEGTDGTVFPPFLTEKDNLESFSDDLCRSFKPWYQKKTSYRGIKTNRYVANIGDFANDPELQCYCDSPDKCPPKGLMDLMKCMKAPMYASLPHYLDSDPQLLKDVKGLSPDANEHGIEIDFEPISGTPMVAKQRVQFNIILLKTDKMDLIKDLPGTMTPLFWIEEGLALNKTFVKMLKNQLFIPKRIVSVVKWLLAGVGFVGLVGSLVYQFKGKMINFALSPSSAQVTKVNPEINQQNQPKDISIIGESQNPPKVDM
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGK_THET2
Sequence: MRTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLAGGASLVLLSHLGRPKGPDPRYSLAPVGEALRAHLPEARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKNDPELSARYARLGEAFVLDAFGSAHRAHASVVGVARLLPAYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFTFLKALGGEVGKSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVETRVFPARAIPVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGRAIAALEGAFTVVGGGDSVAAVNRLGLKDRFGHVSTGGGASLEFLEKGTLPGLEVLEG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METB_ECOLI
Sequence: MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction.  In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia.
What are the official names of this protein?
Cystathionine gamma-synthase, CGS, O-succinylhomoserine (thiol)-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.