PharMolix/UniProtQA huggingface dataset:
Protein: MURC_ANADF
Sequence: MSLFRSRPAKIHFVGIGGIGMSGIAEVLLNLGYAVSGSDLKESEITRRLASLGGRVQRGHAAQHVEQVDVVVTSSAVRKDNPEVVEARRRKIPIIPRAEMLAELMRLKYGVAIAGSHGKTTTTSLAAHLLAHAGLDPTAVVGGKVNTFGSNAKLGRGDYMVVEADESDGSFLHIPPTIAIVTNIDPEHLDHWKTEEALRKGFLDFVNRVPFYGRAILCIDHPTVQSLLPEVESRYVTYGESHQADYRADGIEVSGHAVRFDAFRRDEPLGRFEVRLVGRHNALNALAVVAIADEMGVPADVTREALASFGGVQRRFTVRGEAGGVTVVDDYGHHPAEVKATLLGAREAFHRRVVCLFQPHRYTRTRDLLPEFATAFNDADVLLLTDIYAAGEEPIPGATSEALAEAIRACGHRDVSLVPRPELARAARQRVRPGDIVLTLGAGDITAAGPELLGLLEA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBL_BACSU
Sequence: MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVALDKNSGKVLAVGEEARRMVGRTPGNIVAIRPLKDGVIADFEVTEAMLKHFINKLNVKGLFSKPRMLICCPTNITSVEQKAIKEAAEKSGGKHVYLEEEPKVAAIGAGMEIFQPSGNMVVDIGGGTTDIAVISMGDIVTSSSIKMAGDKFDMEILNYIKREYKLLIGERTAEDIKIKVATVFPDARHEEISIRGRDMVSGLPRTITVNSKEVEEALRESVAVIVQAAKQVLERTPPELSADIIDRGVIITGGGALLNGLDQLLAEELKVPVLVAENPMDCVAIGTGVMLDNMDKLPKRKLS
What is the function of this protein?
Forms membrane-associated dynamic filaments that are essential for cell shape determination (PubMed:11290328, PubMed:19659933).  Acts by regulating cell wall synthesis and cell elongation, and thus cell shape (PubMed:19659933).  A feedback loop between cell geometry and Mbl localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity).  Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes.  The process is driven by the cell wall synthesis machinery and does not depend on Mbl polymerization (PubMed:21636745, PubMed:21636744).  Organizes peptidoglycan synthesis in the lateral cell wall (PubMed:19659933).  Also required for proper chromosome segregation (PubMed:14588250).
What are the official names of this protein?
Cell shape-determining protein Mbl, Actin-like Mbl protein, Rod shape-determining protein Mbl.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane-associated (PubMed:17064365). Localizes in the form of helical filaments that run the length of the cell (PubMed:11290328). Colocalizes with MreB, MreBH and MreC (PubMed:16950129, PubMed:17064365).
Protein: PHS2_GLOVI
Sequence: MNKMTPEEIETALKPIADWQLSEADGATAIERVFRFDDFVQAIAFVNKVAERAETAGHHPDIHIHYNRVRLVLSTHDAGGVTSKDLEMAAAL
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase 2, PHS 2, 4-alpha-hydroxy-tetrahydropterin dehydratase 2, Pterin carbinolamine dehydratase 2, PCD 2.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: WUHO_DROYA
Sequence: MCTTISFAEPEIVLGHGRRVLFVNPDDLQIFKEIELPPDLGLKGLGSQSQESCPAAAAATSTSTATATCAGKEPGGKEQQLTKQPEEGGTTASGSGVTSTSVQNVTYSPDGQLLAVTTSGGQKALLLYRSRPENARLLSTRPLARAASAVRFCSDSSSVLVTDKTGDCYQYDCVELEAPPRLLLGHLSVVYDILWSEDQQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLTDKHIASASGDKTLRVWNYIQGKELLQHELPAPAVRLLVRQLEPEKIFQAAVLFYEHVDALGLYRLERSSDDIWSVTATQLVCAEAGSWSISNFTLTSDRIYVTGAENERLSLRVYDIATGQPATSGVPEGWVKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNVSDYLERKKRRIEEQQQQKCG
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: ATPF_SOLUE
Sequence: MRRLAVYLAIAVGLFAQAPKEGARESLAEKADEAGNKAHAAEEEGSMDIWKWANFLILAGGLGYLVGKNAGPFFAARSAGIRKDMENSLAQQKDAEARAADVDRRLANMEADIAALRGEGERAARAEAERMEQHTAAEIAKIQQHSEQEIASAGKAARMDLKRYAAELAVELAEQKVRARMTPETQDALVQGFVRNLK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MEST_RAT
Sequence: MVRRDRLRRMREWWVQVGLLAVPLLAAYLHIPPPQLSPALHSWKTSGKFFTYKGLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPRPHQYSIFEQASIVESLLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMNFFVFSRGLTPVFGPYTRPTESELWDMWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALASVTIPIHFIYGPLDPINPYPEFLELYRKTLPRSTVSILDDHISHYPQLEDPMGFLNAYMGFINSF
What are the official names of this protein?
Mesoderm-specific transcript homolog protein.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: COAX_LEPIN
Sequence: MLLVVDVGNTNTVFGIFENGNKIPLFHKRTVTRKDRTSDELGLFFRGFLREFKIENEMITGGIYSSVVPTLNPILDRMFQDWFKIEAIRVHYQMKLPFSISYPRPYEIGADRLVNAATCAIDFPGKSIIIDLGTATTFCVVNEKPEYLGGVIAPGLKVSMDALTRNTSQLPPIVFQSPGKILGDSTIESIQAGFFFGWIGLLEGIIREIKKDKGQDYQVIGTGGLVTVIDAAHPGIFDKIDPLLTLRGLQILHLMNS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX5_CAVPO
Sequence: MAMRELVEGECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASETVSKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQEIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFIAEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGAATTDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESVAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLLRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRCTPAYAHLVTPAEEGAGGAGLGSSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYRAADARDLSALLALFGLSQ
What is the function of this protein?
Does not mediate translocation of peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal.
What are the official names of this protein?
Peroxisomal targeting signal 1 receptor, PTS1 receptor, PTS1R, PTS1-BP, Peroxin-5, Peroxisomal C-terminal targeting signal import receptor, Peroxisome receptor 1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal targeting signal receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13) (By similarity).
Protein: RRT5_LACTC
Sequence: MSPTQPNPAAALSGSAEPQTKRIYISNLDFSTTEEELEQFLQEFRVVSVLIPSQTVRGFRNSTVRPLGIGYADFASAADALQAVENLNGKQLRERTLKIKMYVPYSPRARAERRKEKRKVPAPQAEENPDAAPQDAQQPQPPAPAEEPTSKDTVYCAYLPSKVTDVELREFFADYQPQDIYVYRTNGSRRKVYFHRRFTAALVTLGGEAELANAIETLGTRRLMGKKITLRPARLSKVEEVQHAAARKLELEQIQQQTRQIAEHAMAMEEHRQQEAEIPAAETPDDVAATA
What is the function of this protein?
May be involved in the modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription protein 5.
What is the protein family that this protein belongs to?
Belongs to the RRT5 family.
Protein: RL24_PORG3
Sequence: MSKLHIKKGDTVMVISGEDKGHSGRVLEVLVKEQRAIVEGLNMIKKHAKPSAKNPQGGIISKEAPIHISNLNVVDPKTGKATRIGRRLNENGKLVRYAKKSGEEIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CL060_RAT
Sequence: MSSESEKGQERLIQAAKLFSCHIQDLVSFINRFIELFNLTMKTQILPMSLNEESCIKDFLEQMIENFKEMQLMADVKQKEMQKEPLCSKVVTEVTSAGGKCADLSPHHMAEEMLKTIQTSGAALVPKTSHILGSLETSLSLLMQFPIMGLRLSDFHSEETKEQPDATTSEKSRSPECPKTTKEEALKRLQDMLCPENAHKPLETAAEELEQFIKTMDMTLQVLRKSIKTMEGNSCVLTQVQGK
What are the official names of this protein?
Uncharacterized protein C12orf60 homolog.
Protein: LPXC_BURM7
Sequence: MLKQRTIKSIVKTVGIGVHSGRKVELTLRPAAPDTGIVFSRVDLPTPVDIPASALSIGDTRLASVLQKDGVRVSTVEHLMSACAGLGIDNLYVDVTAEEIPIMDGSAATFVFLIQSAGIEEQNAAKKFIKVTKPVEIRDGDKFARLDPYFGFKLKFTIDFRHPAVDKTGQELEVDFANTSYVREIARARTFGFAHEVEMMRELGLARGGSMDNAIVLDEYRILNNDGLRYDDEFVKHKMLDAIGDLYVIGHPLLASYTAYKSGHGLNNALLRELLAHEQAYEIVTFDDPKTAPTGFGFDAQTAFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: METN1_PSEE4
Sequence: MAQASALRAPIPPAEPHKATEQALRPDVNQAHVRFIGLGKTYPGQAQPALHGIDLNIRRGEIFGIIGRSGAGKSSLLRTINRLEQPSQGRVLIDQVDIAPFDEDRLVALRRRIGMIFQHFNLMSAKTVWQNVELPLKVAGVAKAERQRKVRELLELVGLSQKQHVYPAQLSGGQKQRVGIARALVHDPEILLCDEATSALDPETTASILELLRDINRRLGLTVVLITHEMAVIRDICHRVVVLERGEVVEQGEVWQVFGAPRHEVTRTLLAPLQTRLPETLQAGLRASPASRDAAVVLKLSLVGEPELSALFADLGGRVRLLQGGIETIGEHALGQLILSVRGSPLDTRQLLERARGWAADVEVLGHVD
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL28_SHESR
Sequence: MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEEEKRFVQLRVSTKGIRLIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NRAM_I000F
Sequence: MNPNQKLFALSGVAIALSVLNLLIGISNVGLNVSLHLKGEGVKQENNLTCTTITQNNTTVVENTYVNNTTIINKGTNLKAPNYLLLNKSLCSVEGWVVIAKDNAIRFGESEQIIVTREPYVSCDPSGCKMYALHQGTTIRNKHSNGTIHDRTTFRGLISTPLGTPPTVSNSDFICVGWSSTSCHDGVGRMTICIQGNNDNATATVYYNRRLTTTIKTWAKNILRTQESECVCYNGTCAVVMTDGPASSQAYTKIMYFHKGLIIKEEPLRGSARHIEECSCYGHDQKVSCVCRDNWQGANRPIIEIDMSTLEHTSRCVCTGVLTDTSRPGDKPNGDCSNPITGSPGAPGVKGFGFLNGDNTWLGRTISPRSRSGFEMLKIPNAETDPNSRIIERQEIVDNSNWSGYSGSFIDCWDEANECYNPCFYVELIRGRPEEAKYVWWTSNSLIALCGSPVSVGSGSFPDGAQIQYFS
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: AAEB_ECO45
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLTGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPA_BURM9
Sequence: MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALAKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYPPEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLKGVTGAANLDVSSIAGKIPAIKSRVPLPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLEQAVPERAAAELAGFVAELRAAIDGAAKPAA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: GPR4_BOVIN
Sequence: MGNRTLEGCHVDSRMDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVRQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKVKIKRLALSLIAIVLVCFAPYHVLLLSRSAVYLRRPRDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHHLLRFLASDKPQEMANASLTLETPLTSKRNSMAKAMAAGWVAAPLAQGDQVQLKMLPPAQ
What is the function of this protein?
Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA13/Rho pathways.  Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway.  In the brain may mediate central respiratory sensitivity to CO(2)/H(+).
What are the official names of this protein?
G-protein coupled receptor 4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_RIPO1
Sequence: MAHKKGTGSTRNGRDSRAQRLGVKRYGGQVVKAGNILVRQRGTKVYPGNNVGRGSDDTLFALIDGIVTFEYKTRSQKKVSVYPVAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: JIP2_RAT
Sequence: MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEEDEEEEEEEEEEEDGDGDGRAGGGSGSQELSGESLIPSPSIEESHKLRPTTLHLTTLGAQDSLNNNSNGGFTSAPPSSWQETVLRSPVQEPLKELPAPLLPAEEEHHEVQSLARPGCDCEGNQPPEPPASGGASPSSDPGIEADLRSHSSGGHEGRRSSQELSSPGSDSEEAGGARLGRMISSISETELELSSDSGSSSGRSSHLTNSIEEASSPASEPEPEPEPEPLHEPPRRPAFLPVGQDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPPAPRPPEEAASQANPVPQDCPDPEAVAGPHVELVDMDTLCGPPPPAPAAPRLGPAQSGPCLFLSNPTRDTITPLWAPPGRTARPGRSCSAACSEEEEEDEEEDEEDEEDAEDSVIPPGSRTTGSTAPLDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLDNDSEEDSSCEASEEEAGATLLGSDQVPEDASPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCVVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSPCWVDRFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVARSVGRAFLEYYQEHLAFACPTEDIYLE
What is the function of this protein?
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module.  JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells.
What are the official names of this protein?
C-Jun-amino-terminal kinase-interacting protein 2, JIP-2, JNK-interacting protein 2, Islet-brain-2, IB-2, JNK MAP kinase scaffold protein 2, Mitogen-activated protein kinase 8-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the JIP scaffold family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Accumulates in cell surface projections.
Protein: NODD_RHILE
Sequence: MRFKGLDLNLLVALDRLMTERKLTAAARAINLSQPAMSAAISRWRDYFRDDLFIIQRRELNPTPAAEPLAPVVREALLHIQLSVIAWDPINPAEFDRRFRIILSDFMALVFFEKIIVRLAREAPGVSFKLLPLDDDPEELLRRGDVDFLILPDLFMSGAHRKARLFEERLVCVGCSTNEQLQGKLFLEQYMSMGHVAAKFGRGLKPSVEQWLLLQQGLKRRIELVVPGFNLIPPLLSGTNRIATIPLRLVKHYEQTIPLRIIEHPLPLLSFTEAVQWPALHNSDPGNIWMREIMIQEASRHWNPRPKVVRLKRPRSFHSRSS
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RL21_SHEON
Sequence: MYAVFQSGGKQHRVAPGHTVRLEKLEVATGSTVEFDQVLLIADGEKVHVGAPLVAGGKVVAEVVSHGRGEKVTIVKFRRRKHHDKKLGHRQWFTEVKITAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TCC4_MOUSE
Sequence: DKRTDSDFSPKPTIFLPSAAETNLHKAGTYLCLLEKFFPKVIRVYWKEKDGEKILESQEGNTIKTNDRYMKFSWLTVTEDSMAKEHSCIVKHENNKRGVDQEILFPPIGKAFTTINVNPRDSVLRHENVNNATDLEDCMKGRKDMLQLQVTTTYAFYTYLILFFKSMVHLAFVVFCLFRRAAMSCDDQRS
What are the official names of this protein?
T-cell receptor gamma chain C region 5/10-13.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1827_XANC8
Sequence: MNTPLPPGLAQIWVDADACPAVIRDILFRAAQRTGIPVTLVANHFLRTPTLAHVRALQVPGGPDAADDAIAERVNAGDLVVTQDIPLAARVLERGAAAVSPRGEPFSSDSIAERLSVRGFLEELRGAGVATGGPPALHARDRQAFAAQLDRWLARQSARS
What are the official names of this protein?
UPF0178 protein XC_1827.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: AROC1_BACCR
Sequence: MRYITAGESHGPQLTTIIEGVPAGLSLVADDINEELARRQKGYGRGRRMQIETDQVQILSGVRHGETLGSPIALVVENRDFAHWTKIMGAEPLTEQEEKEMKRKVTKPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVAAGAVAKKVLAELGIKVAGHVIEIGGVQAKEITYSSIEELKSITEASPVRCLDDEAGNQMMKAIDDAKANGDSIGGIVEVIVEGMPIGVGSYVHYDRKLDAKLAAAIMSINAFKGVEIGIGFEAAHRPGSEVHDEILWNEEHGYTRRTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLQSVDIDTKEPFTASIERSDSCAVPAASVVAEAVVAWELATALIEQFGLDRMELIRENIEKHNEYARGF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 1, CS 1, 5-enolpyruvylshikimate-3-phosphate phospholyase 1.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FADR_SALPB
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BACC7
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGDVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_AYWBP
Sequence: MHMRSFKIAIDGPAGSGKSTISKKLSQKLGWNHIDTGAMFRALTLYLLENEVSWHNEKSLNQILDKINLSYSCNKIFLNQEDVSLKIKSLDVEKHVSSVALIPGVRTKLLKLQKEICANTPNLIMDGRDIGTVVMPDANLKIFLTANITKRALRKQQEDAQNGKITDITQIMKQLKERDHKDYHRHLAPLSKALDAILLDTTELSIDELIAKITTLIEKKRRA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUGZ_HELPY
Sequence: MLNRIIEHMNAHHVEDMKGLLKKFGQVHHAENVAFKSVDPQGIVIGYNHNQTLRIEFNHEVKDPKDYKNAIIELCQSVEKTHDLKGVEEEVKAFKESFDSVCLATLHPNGHVVCSYAPLMSDGKQYYIYVSEVAEHFAGLKNNPHNVEVMFLEDESKAKSAILRKRLRYKTNARFIERGAEFDKAFDSFIEKTGGAGGIKTIRAMQDFHLIALDFKEGRFVKGFGQAYDILGDKIAYVGDKGNPHNFAHKK
What is the function of this protein?
Involved in heme iron utilization (PubMed:19091096, PubMed:21030596).  Catalyzes the degradation of heme to biliverdin, with the release of iron and carbon monoxide (PubMed:19091096, PubMed:21030596).  Release of iron from heme may play a crucial role in the pathogenicity of H. pylori (PubMed:19091096).
What are the official names of this protein?
Heme oxygenase HugZ.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase HugZ/HutZ family.
What are the subcellular locations of this protein?
Cytoplasm.