PharMolix/UniProtQA huggingface dataset:
Protein: MURE_CHRVO
Sequence: MKSRLTALPDWDPALLQQLGLPIKRVEADSRRVLPGDVFLACRGEYADGRDFIPAALEKGAAAVLWDEADGFAWKAEWQAPNLAVPNLRERAGIVAAHVLGLPSRDLTVVGITGTNGKTSISHWLAQAFSLLGQKAALIGTVGNGFYGHLTETTHTTPDPVTVQQKLAEYRRQGAHVVTMEVSSHGLDQFRVNGVEFATAVFTNLTRDHLDYHGSMEAYGESKKKLFFWEGLKHAVINADDAFGRQLAAGIDPKQTRVVTYGLEQGDVRPLALAATLEGLQLTVATPWGTVDVRTGLVGRFNAANLLACLATLCVNGVSLQDAAAVMARIQPARGRMQSVGGAHEPLVVIDYAHTPDALEKALATLSEIRPAGGRLFCVFGCGGDRDPGKRPMMGAIAEKHADVAVLTSDNPRSEDPQAIIRDVLAGMDAARAHVEADREAAIHWAVAQARVGDVVLVAGKGHEEYQDIAGVKRPFSDFRVAEEALTAWGKRP
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIE1_DANRE
Sequence: QLLQFAADVATGMHYLSDKQFIHRDLAARNVLVGDNLVAKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFSQISVQLNRMQEARKAYVNMALFENFTYAGIDATAEEA
What is the function of this protein?
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
What are the official names of this protein?
Tyrosine-protein kinase receptor Tie-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NU1C_OLIPU
Sequence: MIIYATVVQTINSFVRLESLKEVYGLIWIFVPIFSLVLGIITGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLFKENLRPSRGNTPLFSIGPSIAVISILLSYSVIPFSNHLVLADLNIGIFLWIAISSIAPIGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSLSTVDIVEAQSKYGFWGWNLWRQPIGFIIFLISSLAECERLPFDLPEAEEELIAGYQTEYSGIKFGLFYVASYLNLLISSLFVTVLYLGGWNISIPYISILELFQRDQIFGTTICIFITLAKTYLFLFISIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSFQLFSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1186_COPPD
Sequence: MESGFLNIGFSSYISVSKIIGIVSPDSAPIRRMIRLAKEQGRLVDATFGRRTRAAILTEGGFIVLSAVLPDTLVSRLEEEEEEEERTEPITEQEAELEEESGEDV
What are the official names of this protein?
Putative regulatory protein COPRO5265_1186.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: OSPA_BORBZ
Sequence: MKKYLLGIGLILALIACKQNVSSLDEKNSVSVDLPGEMNVLVSKEKNKDGKYDLIATVDKLELKGTSDKNNGSGVLEGVKADKSKVKLTISDDLGQTTLEVFKEDGKTLVSKKVTSKDKSSTEEKFNEKGEVSEKIITRADGTRLEYTEIKSDGSGKAKEVLKSYVLEGTLTAEKTTLVVKEGTVTLSKNISKSGEVSVELNDTDSSAATKKTAAWNSGTSTLTITVNSKKTKDLVFTKENTITVQQYDSNGTKLEGSAVEITKLDEIKNALK
What are the official names of this protein?
Outer surface protein A.
What is the protein family that this protein belongs to?
Belongs to the OspA lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YF14_SCHPO
Sequence: MTIYYMIVFMLLMVEIVSFVILSLPLPLKVRRAILNAISNSPFAGRVKHVLKITIICILILFADSVRRVVRVTKEYDLAIAAPSTTESARSGYKASQFYAQRNLYLCGSALFLSLVVNRYYLALEAMIAAQDKMQALQTQVEASTNNAKAVEELETLRTKLETRDKEYETLAEKYAAVTKTVEKKKDI
What are the official names of this protein?
Uncharacterized protein C9E9.04.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: MOAA3_MYCTO
Sequence: MTRVFHPALSGPEQSRYQITDVASVSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPKYDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase 3, Molybdenum cofactor biosynthesis protein A 3.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PROB_DEHMB
Sequence: MNENCYKRVVIKLGTSLLTGGTGKLDHERMADLCRQIAELTRLGTEIVIVSSGAIAAGRSKMGIRHIPKDVPFKQVLAAIGQSQLMNYYDQLFSPHGLTVAQGLLTKSDLSDRSGYLNARNTLLALMELGIITIVNENDVVAIDEIQQAKFGDNDNLSAMVANLIEADLLLILTNIRGLYTSDPTLHPEATLITEVKEITEELEQLAAGSSNKLGTGGMVTKLEAARLATSSGVTAIIADGHIPDIILKLANGENEGTRFIPSLHKPDSRQRWMMSGLCTRGSICVDDGAAKALRENQKSLLAAGVQQAEGKFGRGDIVKLTDSHGKRLGYGITNYSSDDISKIKGLHSQELNAVLGGNQGPEVIHRNNLVVI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CG057_MOUSE
Sequence: MRNTSKEVQSTSYRYAPCDWYYHLPVKRSEKPVGAPPASQIPGLSDLRDSPNVNLPRARRYWIKETDSEYVKLAKQGGRPDLLKHFAPGTRQGSPVAYSLPDWYIHHSKPPTSHQREVPVVSIPDYMVYEEFNPDQANGSYESRQGPFDFDRKTIWQREAEELENVKRKVKLPAINSKNPSKTGTPVSHKEPERSRLSLPPMPGQKNSSPTNFSKLISNGYKDEWLQQQKAEADRRTPKTSRASVSSKSTEDSKSNQDTETPENPETPEGSEKTPDAEVSSPSESTPAELK
What are the official names of this protein?
Uncharacterized protein C7orf57 homolog.
Protein: RL33_ALIF1
Sequence: MAKGAREKIKLVSTANTGHFYTTDKNKRNMPGKMEIKKYDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DAPB_PSEE4
Sequence: MRRIAVMGAAGRMGKTLIEAVQQTPGAGLTAAIDRPDSSLVGADAGELAALGRIGVLLCDDLAKVVDEFDVLIDFTHPSVTLKNLAFCRKAGKAMIIGTTGFSVEEKQLLAEAGKEIPIVFAANFSVGVNLSLKLLDMAARVLGDDVDIEIIEAHHRHKVDAPSGTALRMGEVVANALGRDLQEVAVYGREGQTGARDRKTIGFATVRAGDVVGDHTVLFAAEGERLEITHKASSRMTFAKGAVRAALWLDGREPGLYDMQDVLELR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLX5_MOUSE
Sequence: MTGVFDRRVPSIRSGDFQAPFPTSAAMHHPSQESPTLPESSATDSDYYSPAGAAPHGYCSPTSASYGKALNPYQYQYHGVNGSAAGYPAKAYADYGYASPYHQYGGAYNRVPSATSQPEKEVAEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYPSAASSINSHLPPPGSLQHPLALASGTLY
What is the function of this protein?
Transcriptional factor involved in bone development.  Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation.  Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation.  Stimulates SP7 promoter activity during osteoblast differentiation.  Promotes cell proliferation by up-regulating MYC promoter activity.  Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton.  Binds to the homeodomain-response element of the ALPL and SP7 promoter.  Binds to the MYC promoter.  Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
What are the official names of this protein?
Homeobox protein DLX-5.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KGUA_PSET1
Sequence: MAQTRGNLFILSAPSGAGKSSLINALLKKHTDMKVSVSHTTRAKRPGEENGVHYHFVSTDEFKALITKDDFFEWAQVFDNYYGTSKQAIESQLDAGIDVFLDIDWQGAQQVRKIMPSVQTIFILPPSKAELEQRLNNRGQDSQEIIAGRMAQAQSETSHYNEYDFVIVNDDFDTALTDIETIVMAQRLTLKMQSVRHQSLLNSLLK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC5AC_MOUSE
Sequence: MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDKLSTWISKGLCILFGIMCTSMAVVASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVAIGSFIYPAPESKTLPLPLSTEHCVELNITTTVAPQISSRPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSYSNSVPEKTTYF
What is the function of this protein?
Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.  Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate.  May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine.  May play also a role in monocarboxylates transport in the retina.  Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.
What are the official names of this protein?
Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Protein: MOAA_PSEPG
Sequence: MEQNSRALIDGFNRKIDYLRMSVTDRCDFRCVYCMAEDMQFLPRQQILSLEELFQVAERFVALGTRKIRLTGGEPLVRQGIVELCGRIAALPGLRELCMTSNGSQLGRLAQPLFDAGVTRLNISLDSLDTDRFKQLTRTGDLAQVVAGIDAARQAGFKRTKLNCVVLKGRNDHELVDLVRFAIDRELDITFIEEMPLGTISEHERGESFCSSDEVRERLAGQFTLIESTESSQGPARYWRLAEAANTRVGFISPHSHNFCATCNRVRLTVEGRLLLCLGNEHSVDLKHVLRAHPGNPERLEKAIRDSLHLKPYRHHFEVGGEVQILRFMNMTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: H2L01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLVECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1d, U4-TRTX-Hhn1d, Hainantoxin-II-12, HNTX-II-12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_MYCLE
Sequence: MIFAKGHGTQNDFVVLPDVEADVTFTAAQVAALCNRRQGLGADGVLRVTTAGAAVTAGVLEHLPDGVSCSDWYMDYRNADGSVAQMCGNGVRVFAHYLRASGLESCDEFVVGSLAGPRLVNVHHVDELNADVTVDMGKANLLGSGGPAFAVTVGGRRFSGVAVDVGNPHLACMDPQLSLEELAALDLGAPVHLDRVQFPDGVNIEVLTAPVDGMVQMRVHERGVGETRSCGTGTVAAAVAALASAGADTGTLTVRVPGGDVVITITDVTSYLRGPSVLVAHGELADAWWYSLARSC
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_EHRCR
Sequence: MLHSNIYNLQAEATNKILSSSSLEELESIKLYYFGKSGTITACLKSIATISNIEERKSVGSSVNAICAELKSLINSQKEKLHKIQINAQLMQDRVDISLPVRPKQIAKLHPISKTLHEVRHIFSSLGFKLSDGPELEDEFHVFDALNTHKNHPAREENDTFYLKTLVNQKRVVLRTHTSSVQIRVMQANKGNYPIKIIAPGKVYRNDWDATHSPMFHQIEGLYIDKNVNMGHLKYCIHYFLKKFFGENIQIRFRNSYFPFTEPSAEVDIKCGEKDWIEILGCGMVHRNVLTNVNIDPDQYSGFAFGIGIERVAMLKYNISDLRKFYSNKLQWLNHYGFCFTHLVSC
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_BUCA5
Sequence: MIKSELFERIAEQKINISNKMIERAAKEMLEHMIISLANGKRIEIRGFGSFSLHYRSSRIGRNPKTGKSVKLNEKYVPYFKPGKKLRDRANIHK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL22_DESRM
Sequence: MEAKAIAKFIRVSPRKARMVVDLIRGKKVEEALAILRYTPNKAAAAVTKVVKSAAANAEHNNDMDKEELVVSQIFVDQGPSLKRMMPRAMGRADIIKRRTSHITVVVSDKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: M1_I59A0
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: GLYA_BORGP
Sequence: MRDDQIFNLIEKEKLREKEHIKLIASENFTSLEIRQAVGSILTNKYAEGYPLNRYYGGCSFVDEIESLAILRAKELFGAKYANVQPHSGSQANMAAIMALINPGDRILGMQLSHGGHLTHGSRVNFSGIFFNTYFYGVSRDSELIDYDEVLKIARDCRPNLIIAGASSYSREIDFKKFREIADDVSAYLLCDIAHIAGLIVAGFHNSSIDVAHLTTSTTHKTLRGPRGGIILSGKDFDKLVTFNGKEKALFNAVNSTVFPGTQGGPLVHVIAGKAIAFREALQESFREYIANVIKNTKVMAEYFKSEGFRIVSGGTDNHLFLVDLSNLDLTGADAEKLLEGVNITLNKNAIPFDKKSPSLASGIRIGGAAITSRGLNENDSLNVAKFIVRALKTRSDIELKQIKKEVVRFIRDFDMP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SI176_DICDI
Sequence: MLFKSLQSISSVKSVSQKSQLTNTINSTQFGSNSNQLLAVAACIDLNLAPLLSAHIDAFISL
What are the official names of this protein?
Protein sigN176, SrfA-induced gene N-like protein 176.
Protein: VPS10_YEAS8
Sequence: MILLHFVYSLWALLLIPLINAEEFTPKVTKTIAQDSFEILSFDDSNTLIRKQDASVTISFDDGETWEKVEGIEDEITWIYIDPFNRHDRAVATSMYESRLYITNDQGKSWERITLPDSEKNISSRGCYIETHPLNKNYFLAKCNYCEKTEVDNEENSGDEEGAPVIFNITHCTDKVFASNDGGKSFSEIKSSLERNENSAISISDCGFAKTGKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVITQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINLYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKNKGVTKISVDNGLTWTVLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIRRVDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLSSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHVISKIRERFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDALPEGNEENIDRPDSTAPSNENQ
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.  Binds the Golgi-modified P2 form of CPY, and this interaction is dependent on the presence of an intact CPY vacuolar protein sorting signal (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein PEP1, Carboxypeptidase Y receptor, CPY receptor, Carboxypeptidase Y-deficient protein 1, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10, Vacuolar protein sorting-associated protein 10, Vacuolar protein-targeting protein 1.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: GNKL_PICAB
Sequence: APNTNFVSSACNTQKIPSGNPFFNNLGAMLADLKQNTAFSGYDYKTSRAGSGGAPTAYGRAICKSSISQSDCTACLSNLVGRIWGICSNAIGARVQLTDCFIQYEQHSF
What is the function of this protein?
Exerts antifungal activity through its carbohydrate-binding specificity.
What are the official names of this protein?
Antifungal protein ginkbilobin-like protein, Embryo-abundant protein 24.
Protein: DAPA_VIBC3
Sequence: MFSGSIVALITPFTPDGEVDYISLKKLVDFHVDAGTDAIVSVGTTGESATLTVEEHVKVVAKTVEFAEGRLPIIAGTGANATHEAVTFSRLLNNTGIAGYLSVTPYYNKPTQEGLFLHYNAIAQETDIPVILYNVPGRTAVDMRPETVARLSEIKNIVALKDATGDLSRVAKHREMCKEGFVLLSGDDATGLEFVKLGGQGVISVTNNIAAADMAKMMHLALDGKFDEAASINQRLMTLHKNLFIESSPIPVKWAAHKMGLIANGDLRLPLTQLSEPARPIVAQALSEACIY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_THENN
Sequence: MVRVKICGITNLEDALFSVESGADAVGFVFYSKSKRYVSPEKAREISLNLPPFVFRVGVFVNESLESVLDIAFHAGLNAVQLHGDESVEFCERLNEKIMVIKAVGISEEQDVRRALEYRKFPVLLDTKVSGYGGSGKVFNWSVVLPYRDQFRYLILSGGLNPRNVERAIEMVRPFAVDVSSGVEISPGKKDHNLVREFIKKAKGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SPY2_MOUSE
Sequence: MEARAQSGNGSQPLLQTAHDSGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQPSQVHSSRAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGPSFSHGPAAADGIIRVQPKSELKPGDVKPLSKDDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
What is the function of this protein?
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2 (PubMed:29501879).  Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis (PubMed:10498682, PubMed:10074434, PubMed:29501879).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (PubMed:25576668).  Inhibits CBL/C-CBL-mediated EGFR ubiquitination (By similarity).
What are the official names of this protein?
Protein sprouty homolog 2, Spry-2.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF (epidermal growth factor).
Protein: ASSY_HYDCU
Sequence: MSQIKKVVLAYSGGLDTSIIAKWLQEEYQCEVVTFTADIGQGEEVAPARAKAEAMGIKEIYIEDLREEFARDFVFPMMRANAIYEGEYRLGTSIARPLISKRLVEIAQETGADAISHGATGKGNDQVRFELNAYALMPDVKVIAPWREWDLLSREKLMAYAEEHNIAIEKKKGKKSPYSMDANLLHISYEGGIIEDPANEPEEDMWLWSVSPENAPDQPTYIDISYEKGDIVAINGEAMSPATVMEYLNKVGGENGIGRDDIVENRFVGMKARGCYETPAGTIMLKAHRAIESLTLDRNAAHLKDELMPKYAEMIYNGFWFSPEREMLQALIDQSQDYVSGDVRLKLYKGNVIVVGRTSENSLFDEDIATFEDDGGAYNHKDAEGFIKLNALRLRTAAKKRR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_ENT38
Sequence: MTSVASSSSRIVTESPVVVALDYNNRDSALAFVDLIDPRDCRLKVGKEMFTLFGPQIVRDLQQRGFDVFLDLKFHDIPNTTAHAVAAAADLGVWMVNVHASGGARMMTAAREALIPFGKDAPLLIAVTVLTSMEASDLLDLGVTLSPAEHAERLARLTQNCGLDGVVCSAQEAVRFKSALGHNFKLVTPGIRPQGSDAGDQRRIMTPEEALAAGVDYMVIGRPVTQSADPALTLKAINASLGKVTG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.