PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_HERAR
Sequence: MNIHEYQGKEILRKYGVTTPKGFPCFSVDEAVQAAEKLGGKVWVVKAQIHAGGRGKGGGVKVAKSLDEVRKYANDILGMTLVTHQTGPEGRLVKRLLIEEGADIKKELYVGMVVDRGSQRVALMASSEGGMDIEHVAEHTPEKIHKVFIDPFKGLLDSEADDIARKIGVPEGSIPQARAFMQGLYKAFDETDASLAEINPLIVTGDDRIVALDAKFNFDSNALYRHPEIVEMRDLDEEDPAEIEASKFDLTYISLDGNIGCLVNGAGLAMATMDVIKLYGGSPANFLDVGGGATTEKVTEAFKIMLKNPDIKAILVNIFGGIMKCDVIAQGVIAAAKQVDLTVPLVVRMAGTNEELGKKILAESGLPIITANNMAEAAEKVVNAAQGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y1752_SULIM
Sequence: MSAPNSYDDEELEELLRRKAAQEQKRLEEERKRKAELESQKESILRVILTPEARQRLTNIKLVKPEFAESLENQLIALAQSGRIKVPLTDEELKQILEQISEQNRRDFKIQIRERGWK
What are the official names of this protein?
DNA-binding protein M1425_1752.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: UPPP_GEOSW
Sequence: MDIVEIIKAIILGMVEGLTEFAPVSSTGHMIIVDDMWLKSQEFLGKYAANTFKVVIQLGSILAVVVVFKDRFIDLLGLRGRHRDGKPRLKLMQVIVGLIPAGVLGVLFEDYIDEHLFSTATVLIGLVLGALLMIAADVFAKKAPKAQTVDQITYKQALIVGLVQCLSLWPGFSRSGSTISGGVLVGMSHRAAADFTFIMAVPIMMGASVLSLLKNWQYFTIDALPFFTAGFISAFLFALISIRFFLKLINQIRLVPFAVYRIVLALVIYIVYF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCSB_EXISA
Sequence: METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLRGLKGFEYLHMRDYDEVTRQALMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQTLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTCPSNIGTGLRASVMLHLPGLTLTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQVIQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDWSPPKFHELIVRLQSGFLQKHFGKTLSTQERDRERATLVRRTLDQGLV
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PG159_VARV
Sequence: MVSILNTLRFLEKTSFYNCNDSITKEKIKIKHKGMSFVFYKPKHSTVVKYLSGGCIYHDDLVVLGKVTINDLKMMLFYMDLSYHGVTSSGVIYKLGSSIDRLSLNRTIVTKVNNNYNNYNNYNNYYNCYNYDDTFFDDDD
What are the official names of this protein?
Protein OPG159.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG159 protein family.
Protein: GATB_LACDA
Sequence: MNFTSTIGLEVHFELKTKSKIFSPSPVTYGAKPNTETNVIDWGYPGTLPMVNKEVYRLGLMVALATHSHVNPVTHFDRKNYFYPDNPKAYQITQFFKPLAENGYVEVEVHGKKKKIHIHEMHIEEDAGKNTHGTNGFSYVDYNRQGVPLLEVVSEPEMTDPDEAVAYLEKLREIVQFTGASDVKMEEGSMRIDTNISIRPAGQKELGTKVEMKNLNSFEHVRMSLAYEQKRQQEILLSGGRVRLSTRRFDTNTGKTVLERVKEGDADYRYFPEPDLPPYHIKQEWVDEIAANLPKTADERRKIYVDEYGLKPYDANVLLQNKESSDFFDATVAAGADPQQAANWMNTQVNGYLNEKHAELKDIALTPENLAAMIKLISDGTISSKIAKKVFAETVANGTDPKKYVEENGMAQLSDESVLAPMVKEVVDANPQSVEDYKNGKDRAIGFLVGQIMKQTRGKANPKVINKLLLADLASR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: IBB1A_LATSA
Sequence: GDDVLSACCD
What is the function of this protein?
Inhibits trypsin (IC(50)=2. 7 nM) and alpha-chymotrypsin (IC(50)=322 nM).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor 1a, LSI-1a.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: RH15_ARATH
Sequence: MGDARDNEAYEEELLDYEEEDEKVPDSGNKVNGEAVKKGYVGIHSSGFRDFLLKPELLRAIVDSGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLSTLQQIEPSPGQVSALVLCHTRELAYQICNEFVRFSTYLPDTKVSVFYGGVNIKIHKDLLKNECPHIVVGTPGRVLALAREKDLSLKNVRHFILDECDKMLESLDMRRDVQEIFKMTPHDKQVMMFSATLSKEIRPVCKKFMQDPMEIYVDDEAKLTLHGLVQHYIKLSEMEKNRKLNDLLDALDFNQVVIFVKSVSRAAELNKLLVECNFPSICIHSGMSQEERLTRYKSFKEGHKRILVATDLVGRGIDIERVNIVINYDMPDSADTYLHRVGRAGRFGTKGLAITFVASASDSEVLNQVQERFEVDIKELPEQIDTSTYMPS
What is the function of this protein?
ATP-dependent RNA helicase involved in pre-mRNA splicing.  Required for the export of mRNA out of the nucleus.  In addition to ssRNA and dsRNA, binds dsDNA, but not ssDNA.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 15, UAP56 homolog A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes predominantly to euchromatic regions of the nucleoplasm.
Protein: IF4G2_CHICK
Sequence: QVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
What is the function of this protein?
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection.  Cleaved by some caspases and viral proteases (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, p97.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
Protein: Y966_CORGL
Sequence: MFGAEDPANSSLVDNLGLTLPWSLNDPHFLTAGFSASTTTAALMSTLWIIVFAVPSERILGSLKFAITAALIHITSIPLGIGIAHLIEEADLNRWGNNMLADVLLTPDFWVFGVAAFASASMPLLWRRRTRLFLFTITLTLLLYTGTLADVTMLTATIIGTVAGELNRHRKTPGGRWLPGSLTVREARIMTAILVTAVAAGPVLAALNPLTHGPFSSATKLIWQPLVTEEHMHHLCHTDSTSDACQGALDQLQQHGVGPSVANLIPLILTVVLAMGLSRGRRLAWILAVLAQLISIAVLMFQLTKLSADSTDLLWSVNAFSVIVPWLVALAVLVFSRRAFQVKIDTTRISKSLGALMVTWLATAALWILATLFLPHAFHPHPTLGLAFKELPFRYLPPTIETVLSHQLFPRSPAGWAVFEWTGTLFWLVVAATLYHLLMGVPSNKAHEDQENAATLLRSGSGDHLSWMTIWGGNTYWWAPENAGYVAYRVKRGIAITLGEPILGPDSSVSKAELAAQFEEFASNQGWIVAWYSVCEEFSKERINAGHHTLRVAEEAVLSSANADFKGKHFQNVRTARNRAAKEGVSSIWTTWADLSAEMQHKIITLSEEWVSDKALPEMGFTLGTVNELSDPDTYLLLAIDEEEHLHGVTSWLPVYEKGRIVGYTLDVMRRDPQGFKSVIEFLISEAVVIARDHDLEWMSMSGAPLSTPPGVADDGTIGQILELLGRAMEPFYGFRSLAASKNKFHPEHHGWYLCYRDELSLPSIGLAVAACYLNEFPLPNWLKKTATSAPSHS
What are the official names of this protein?
Uncharacterized protein Cgl0966/cg1103.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMNP_BACSU
Sequence: MKVKKLVVVSMLSSIAFVLMLLNFPFPGLPDYLKIDFSDVPAIIAILIYGPLAGIAVEAIKNVLQYIIQGSMAGVPVGQVANFIAGTLFILPTAFLFKKLNSAKGLAVSLLLGTAAMTILMSILNYVLILPAYTWFLHSPALSDSALKTAVVAGILPFNMIKGIVITVVFSLIFIKLKPWIEQQRSAHIH
What is the function of this protein?
Mediates uptake of riboflavin and roseoflavin, a toxic riboflavin analog; may also transport FMN.  Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).
What are the official names of this protein?
Riboflavin transporter FmnP, FMN permease, Riboflavin ECF transporter S component FmnP.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNC_CHLMU
Sequence: MQRTVNIQAVESKLKFTFSQPRLLVTALTHPSYRNEFPSDGEDSERLEFLGDAVLGLVVTEHLFLLFPSLNEGLLSTTRSALVNAEACFNYTQKLSLGEHLLIGRGEKMQSHRGKISAYANLFEAILGAVYLDGGLAPARQIIVPLLPNKEAILPLMLVNPKNRLQQFTQQTLKVLPTYIALPWSSEDGTPGYHVQVFVNEKLWGEGFAGSKKEAEKLAAKQALSTHDDNKN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_ROSCS
Sequence: MFEPVATARQRAVACCTFTTEQEDVVQWLVWALPALVIGLAIGAGIGILIYKNSVQSQIRQIEAEARLQLEATRSEQKDLILRATDEALRLRTEAEAQIREARAALAKQEERLQRKEENLDRKIEGLERRERQLQQRERQMEQLHQEAEHLRQQQRAELERISALSQEEARAIILKRVEDETRDEAARRIREIEKTMHEEADKLARKVISMAIQRCASDYVAEVTVSTVALPSEELKGRIIGREGRNIRAFEQLTGVDIIVDDTPEAVTLSCHDPVRREVARLALIKLLKDGRIHPTRIEEVVHKTQQEVDQVMREEGERVAYEANVQGLHPDLIKLLGRLKYRTSYGQNVLQHSLECALLAAHIAAEIGANINVAKTAALLHDIGKAVDHEVQGPHALIGAEIARRLGKSPAIVHAIAAHHNDEEPQTVEAWLVQAVDAISGGRPGARRETLDLYIKRLEALETVATSFSGVQRAFAVQAGREVRVMVQPDAIDDLGSIHLARDVAKKIEESLQYPGQIKVTVIRETRAVDYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TYW1_PONAB
Sequence: MDPSMDTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIKTQGRNLQEKSVPKAAQDLMTNGYVSLQEKDVFVSGVKIFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEAAIDFRFGKTYLKGMRYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEADFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQRGSEEREEGSHEQDELHHRDTEEEEPFESSSEEEFGGKDHQSLNSIVDVEDLGKIMDHVKKEKREKEQREEKSGLFRNMGRNEDGEIRAMITPALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWRRFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCGESSASSLTMAHVPWHEEVVQFVCELVDLIPDYEIACEHEHSNCLLIAHKKFKIGGEWWTWIDYNRFQELIQEYEDSSGSKTFSAKDYMARTPHWALFGANERGFDPKDTRHQRKNKSKAISGC
What is the function of this protein?
Probable component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1, Radical S-adenosyl methionine and flavodoxin domain-containing protein 1, tRNA wybutosine-synthesizing protein 1 homolog, tRNA-yW-synthesizing protein.
What is the protein family that this protein belongs to?
Belongs to the TYW1 family.
Protein: KCY_THET2
Sequence: MRGIVTIDGPSASGKSSVARRVAAALGVPYLSSGLLYRAAAFLALRAGVDPGDEEGLLALLEGLGVRLLAQAEGNRVLADGEDLTPFLHTPEVDRVVSAVARLPGVRAWVNRRLKEVPPPFVAEGRDMGTAVFPEAAHKFYLTASPEVRAWRRARERPQAYEEVLRDLLRRDERDKAQSAPAPDALVLDTGGMTLDEVVAWVLAHIRR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_PELUB
Sequence: MKKISLIGAGQIGGTLAHLIGTKEVADEVVLFDVASGIAKGKALDIAQSSSVDGFNVKFSGTDNYEDIKDSDVIIITAGVPRKPGMSRDDLLGINLKIIKQVAEGIKKNAPNAFVICITNPLDVMVMAFQKFSGLPANKVVGMAGILDSSRFKLFLSLELNVPVKEIEAMVMGGHGDTMVPLPRFTKVSGKPLLDLVKEGKISPERLEEINQRTRDGGAEIVKYLEKGSAFYAPAASGVQMAEAYLKDEKKLLPCAVHLNGEYGVSNVYAGVPVIIGKDGVEKIEQIDLDEKEKKEFMHSIDAVKALWEAASKIDPDLSK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: CREST_HUMAN
Sequence: MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILEYQSKGKTAECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALTQSGSSQGLHSQGSLSDAISTGLPPSSLLQGQIGNGPSHVSMQQTAPNTLPTTSMSISGPGYSHAGPASQGVPMQGQGTIGNYVSRTNINMQSNPVSMMQQQAATSHYSSAQGGSQHYQGQSSIAMMGQGSQGSSMMGQRPMAPYRPSQQGSSQQYLGQEEYYGEQYSHSQGAAEPMGQQYYPDGHGDYAYQQSSYTEQSYDRSFEESTQHYYEGGNSQYSQQQAGYQQGAAQQQTYSQQQYPSQQSYPGQQQGYGSAQGAPSQYPGYQQGQGQQYGSYRAPQTAPSAQQQRPYGYEQGQYGNYQQ
What is the function of this protein?
Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons.  Recruits CREB-binding protein (CREBBP) to nuclear bodies.  Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex.  In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex.  Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex.  At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation.  The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
What are the official names of this protein?
Calcium-responsive transactivator, SS18-like protein 1, SYT homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SS18 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to nuclear bodies. Colocalizes with SGO1 at kinetochore (By similarity).
Protein: RIMP_XYLFM
Sequence: MSDKGIEIVNLLAPKVEMLGFDLLGAEYVLVPSGAILRLYIDIPFAMQPECMVSIDDCERVSREVSAYLDLEEPISGNYTLEVSSPGLDRRLFTLEQFARHHNHLVKVGLKLQQHGSRRLQGKIVRVEQVGGFVVLLVNGVELAVDFNNIDKARIVPDWSALGLAPLEKSKHDTKKMSQGNKKPSNESAARQAVRGVIR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRAP_RAT
Sequence: MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
What is the function of this protein?
Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton (PubMed:11461150).  Involved in autophagy: while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).  Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (By similarity).  Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination a nd degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction.  Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation (By similarity).  Involved in apoptosis (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Cytoplasmic vesicle. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae (PubMed:11461150). Colocalizes with microtubules (PubMed:10899939). Localizes also to discrete punctae along the ciliary axoneme (By similarity).
Protein: S6A12_CANLF
Sequence: MDRKVAVPEDGPPVVSWLPEEGEKLDQEGEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFTCGIPVFFLEVALGQYTSQGSVTAWRKICPLLQGIGLASVVIESYLNIYYIIILAWALFYLFSSFTSELPWTTCTNTWNTEHCMDFLNHSGARTATSSENFTSPVMEFWERRVLGITSGIHDLGALRWELALCLLLAWLICYFCIWKGVKTTGKVVYFTATFPYLMLVILLIRGITLPGAYQGVIYYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFAAGFVVFSILGFMAQEQGLPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASMDMFPSQLRKSGRRELLILAIAVFCYLAGLFLVTEGGMYIFQLFDYYASSGICLLFLAMFEVICISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSQYTPLKYNNIYVYPPWGYSIGWFLALSSMICVPLFVIITLLKTRGSFKKRLRQLTTPDPSLPQPKQHLYLDGGTSQDCGPSPTKEGLIVGEKETHL
What is the function of this protein?
Transports betaine and GABA.  May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
What are the official names of this protein?
Sodium- and chloride-dependent betaine transporter, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PELO_THEON
Sequence: MQIIHEDPKEGKVKVKAETLDDLWHLYHIIDEGDVVYAKTLRKQSQRSDSLRAEKVEVIPVFLGVRAEKINFHKFANQVRVTGPIVYASREDVPLGKYHTIAIEEGTVVTIQKPRWKEHHIERLREAVSASKRARVMIVVIDDGEADMALVREYGVEILTSIRHNLGGKRYNTDREAEEKRFFHDVAKTMEEIMNREKVEKAIVAGPGFVKEDFYKFLRENYPELVKKVVIEDTSVTGRTGIYEVIKRGTVDRVYHENRVAKEVQLIEKVLENIAKNNGLVAYGLREVEEAANYGAVETLLVLDELLKGEMREKIEELMDAVRYSRGEVVIVSSEHEGGEKLKALGGLAALLRFRVK
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_RICTY
Sequence: MSNYWLNFYKPKGISSAKLVNIVKKIIGKTKIGHAGTLDVEAEGILPLAVGEATKLIQLLIDAKKTYIFSVKFGAQTDNGDYTGKVIASKNYIPSQEEAYAVCSKFIGNIKQIPPMFSAIKVNGIRAYKLAREGKVVELKPRNVTIYDLKCLNFDKEKAIATYYTECSKGTYIRTLTEDLALSLQSLGFVIELRRTQVGIFKEENAIHIKASDAITKNFIDKKSIKIEAILDDILVLDATDDQAQKIKYGQKCVFDYEEDVNFLWVRYNGTLLAIGSLNKSCFNSLRVFNLL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SYK_ACTP2
Sequence: MSEVEHQELDLNGEMLARREKLAKLREQGNPFPNTFRRDAYAEKLHAQYDEVEGEALKEQDIQVKVAGRIMLKRVMGKASFFTIQDVSGQIQLYVARDNLAEGVYADKVSMWDLGDIVGVAGTLFKTKTGELTVRCSEVELLTKSLRPLPNKVQGLTDQETRYRQRYLDLISNEESRRTFMIRSKVVSGIRQFFLEKDFIEVETPMLQVIPGGAAAKPFITHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMIEYYQAYADYHDLMDNTEELLRKLAIDILGTTTVPYGEYVFDFGKPFERITMHDAIVKYGNGITREDLDSFEKSVEIAKGLGIEIQKSWGLGSVVNAIFEEVAEHQLIQPTFLMAHPAEISPLARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQAERFDAQVAAKDAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRLAMIFANAPSIRDVILFPAMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BASI_HUMAN
Sequence: MAAALFVLLGFALLGTHGASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQGPNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRAPRVKWVRAQAVVLVLEPGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS
What is the function of this protein?
(Microbial infection) Promotes entry of pentamer-expressing human cytomegalovirus (HCMV) into epithelial and endothelial cells.
What are the official names of this protein?
Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Hepatoma-associated antigen, HAb18G, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF.
What are the subcellular locations of this protein?
Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single-pass type I membrane protein. Endosome. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single-pass type I membrane protein.
Protein: MYB58_ORYSJ
Sequence: MARAPGGVRRRSGRRGAGGGGAGGGGEALRKGPWMAEEDEVLLEHVRTHGPMDWSSIRSKGLLPRTGKSCRLRWVNKLRPNLKSGCKFTAEEERVVIELQAQFGNKWARIATYLQGRTDNDVKNFWSTRQKRLARLLRGPLPAARPNKHNSGKGKAPSSSSLDSQTATFHQSSASLDQASLEGNSLGWQCREAAPFMGYDQACSGFFAFEGPLPLQLLPPADGEASSSNAAQSAPPPLLFDQPPYPLINFPGWPERYVDVGHGFVDAGAMDGLAYQELLPMVQSVPMIMPFFGMECAHDAVKHGAFDDLPPNMFDDAVDQPPPPPPPPPPPSPSPSPSRDDVL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Probable transcription factor MYB58, OsMYB58.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSA_SULTO
Sequence: MSENLWKKALELFAGGVNSPVRAAVKPYPFYVEKSEGAFLYTIDGQRLIDYVLGYGPLILGHAHPYVKKKIIEQIEKGWLYGTPSKKEIELAEKIRSHIPSAEKIRFVNSGTEATMLAIRLARGYTKREKILKFDGNYHGAHDYALINAGSAVSEFNVIISSGIPTSIINTVIVCKYNDLDCVEKHLRTEEIAGVIVEPVMGNMGVILPEQDFLNGLRELTKTYNSVLIFDEVITGFRLGLSGAQGYFKVIPDLTTLGKIIGGGLPIGAVTGKKEIMSNLTPEGKVFNAGTFNANPLTMAAGIATIEVLETTNAYDIANKASKEIAEELDNSLSKKNFKYTINRIQSMFQFFIGISKVTNADDARLANKDLYVKIHEKLLKLGVFIPPSQFETIFTSSSHSDEIVNLTIEAIHKVVSEI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.