PharMolix/UniProtQA huggingface dataset:
Protein: YACG_SALG2
Sequence: MSDVTVVNCPTCGKPVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIASSGDQSDSDDWSEER
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: ECTC_NITOC
Sequence: MIVRDYNKAKETDRRVVASQWESVRLLLKSDNMGFSFHITTIYEGAELPMEYKHHLESVYCLSGEGEVETLADGKIHPIRPGVIYILDHNDQHILRAKTEMQMACVFNPPLTGKEVHDSSGAYPLEAEAVTAD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: TN5P_ECOLX
Sequence: MITSALHRAADWAKSVFSSAALGDPRRTARLVNVAAQLAKYSGKSITISSEGSEAMQEGAYRFIRNPNVSAEAIRKAGAMQTVKLAQEFPELLAIEDTTSLSYRHQVAEELGKLGSIQDKSRGWWVHSVLLLEATTFRTVGLLHQEWWMRPDDPADADEKESGKWLAAAATSRLRMGSMMSNVIAVCDREADIHAYLQDKLAHNERFVVRSKHPRKDVESGLYLYDHLKNQPELGGYQISIPQKGVVDKRGKRKNRPARKASLSLRSGRITLKQGNITLNAVLAEEINPPKGETPLKWLLLTSEPVESLAQALRVIDIYTHRWRIEEFHKAWKTGAGAERQRMEEPDNLERMVSILSFVAVRLLQLRESFTLPQALRAQGLLKEAEHVESQSAETVLTPDECQLLGYLDKGKRKRKEKAGSLQWAYMAIARLGGFMDSKRTGIASWGALWEGWEALQSKLDGFLAAKDLMAQGIKI
What is the function of this protein?
Mediates transposition of transposon Tn5 by a 'cut and paste' mechanism.  First, the monomeric transposase binds the 19 bp inverted DNA repeats flanking the transposon.  Then, dimerization of the DNA-bound transposase creates a synaptic DNA complex.  After nicking of the first DNA strand, excision of the transposon proceeds through a series of intermediates.  The transposase then mediates the insertion of the transposon at a new site by strand transfer.  The activity of the wild-type transposase is very low, and is further inhibited by dimerization with the transposase inhibitor (inh).
What are the official names of this protein?
Transposase for transposon Tn5, Tnp.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: HRCA_BREBN
Sequence: MLSDRQQMILNAIVDNYIHSAEPVGSRTISKRDDIGFSSATIRNEMSDLEELGYLEQPHTSAGRVPSTKGYRFYVDNLIQPHLLEETELGKLKQLFAERILHAEQVVEYTAQILSQLTNYTAIVLGPEIFEHRLKHIQIVPLNAEQAVAIVVTHTGRVENKLIDLPEGIGAGEIEKLVNLLNAKLTDVPLWQLRQRLYQEISGEMQRHTEQYEEILQLLNNSLTQEEERVYLRGATKIMNQPEFRDVDKVKDILELLEQHDQLMNVIGMQGDGLTVRIGQENQLDAIKQCSIITTSYSLGGKPVGMVGILGPTRMEYGKVITVLNHLAEGLSRMLTSQFEK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL19_PROMA
Sequence: MTEDLKNTSPSKEESNEIEESSKATPKATRETKPKDSPSKTKLSAQALIAQFEKSQQKKKVPEVYVGDTVRVGVRISEGNKERVQPYEGVIIAKRHGGLNQTITVRRIFQGVGVERVFMVHSPQVASIKVERRGKVRRAKLFYLRDRVGKATRVKQRFDR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: POLS_EEVV3
Sequence: MFPFQPMYPMQPMPYRNPFAAPRRPWFPRTDPFLAMQVQELTRSMANLTFKQRREAPPEGPPAKKPKREAPQKQKGGGQGKKKKNQGKKKAKTGPPNPKAQNGNKKKTNKKPGKRQRMVMKLESDKTFPIMLEGKINGYACVVGGKLFRPMHVEGKIDNDVLAALKTKKASKYDLEYADVPQNMRADTFKYTHEKPQGYYSWHHGAVQYENGRFTVPKGVGAKGDSGRPILDNQGRVVAIVLGGVNEGSRTALSVVMWNEKGVTVKYTPENCEQWSLVTTMCLLANVTFPCAQPPICYDRKPAETLAMLSVNVDNPGYDELLEAAVKCPGRKRRSTEELFKEYKLTRPYMARCIRCAVGSCHSPIAIEAVKSDGHDGYVRLQTSSQYGLDSSGNLKGRTMRYDMHGTIEEIPLHQVSLHTSRPCHIVDGHGYFLLARCPAGDSITMEFKKDAVTHSCSVPYEVKFNPVGRELYTHPPEHGAEQACQVYAHDAQNRGAYVEMHLPGSEVDSSLVSLSGSSVTVTPPAGTSALVECECGGTKISETINTAKQFSQCTKKEQCRAYRLQNDKWVYNSDKLPKAAGATLKGKLHVPFLLADGKCTVPLAPEPMITFGFRSVSLKLHPKNPTYLTTRQLADEPHYTHELISEPVVRNFSVTEKGWEFVWGNHPPKRFWAQETAPGNPHGLPHEVITHYYHRYPMSTILGLSICAAIVTVSIAASTWLLCKSRVSCLTPYRLTPNARMPLCLAVLCCARTARAETTWESLDHLWNNNQQMFWIQLLIPLAALIVVTRLLRCVCCVVPFLVVAGAAGAGAYEHATTMPSQAGIPYNTIVNRAGYAPLPISITPTKIKLIPTVNLEYVTCHYKTGMDSPAIKCCGSQECTPTYRPDEQCKVFTGVYPFMWGGAYCFCDTENTQVSKAYVMKSDDCLADHAEAYKAHTASVQAFLNITVGEHSIVTTVYVNGETPVNFNGVKLTAGPLSTAWTPFDRKIVQYAGEIYNYDFPEYGAGQPGAFGDIQSRTVSSSDLYANTNLVLQRPKAGAIHVPYTQAPSGFEQWKKDKAPSLKFTAPFGCEIYTNPIRAENCAVGSIPLAFDIPDALFTRVSETPTLSAAECTLNECVYSSDFGGIATVKYSASKSGKCAVHVPSGTATLKEAAIELAEQGSATIHFSTANIHPEFRLQICTSYVTCKGDCHPPKDHIVTHPQYHAQTFTAAVSKTAWTWLTSLLGGSAVIIIIGLVLATIVAMYVLTNQKHN
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to cell receptor LDLRAD3 and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: RL31_VIBCH
Sequence: MKAGIHPEYKAVNATCSCGNSFVFNSTLGKDTMHLDVCDKCHPFYSGKQRIVDTGGRVERFNKRFGALSAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: METN_STRP6
Sequence: MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSANALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQKFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: T1151_CLOPF
Sequence: MNKKLKYLSKSIKESFDINEINKIAKDSKFIQRKGSITAKDFLMFNVFYGSDICTAPLSQLAAKYDMIFSKQLPKQALDKRFNKYSVEFMKEIFIKFLYSQNNTLTNLERTLRTYFDRVIINDSISFTLPKEFKKKFPGSGGVASPSSIKVQLQYELLTGSFMNIDIFSGIKNDVEYLKTMKKYKDYKDLKLADLGYFKIDYLKRLDKSGTAFISKVKSNTSLYIKNPSPEKYKVGTIKKSSEYIKIDIIKLAEPLAAGETIELTDIYIGSKKELKSRLIITKLTEENKSKRIFNHIEGIKKKRLTLNQRRLDFNSINAYITNVSSNIITMNQVHELYSLRWQIEIIFKVWKSIFKINQVKKVKLERFMCFLYGRLIALLLSSTIVFTSKSIILEVDEKEISELKAFGNLIQYFPKLSFEIFKGEFYISRILKSVLSNFKRFGIKSKKNYKKTAFNILKLIKLESFEVTRFAI
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Transposase for insertion sequence element IS1151.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: TAUE1_ARATH
Sequence: MTINLVPLLLSLITIFTIFNPSALADQSQIRSTTSQWLHFSEDLSQSTIEVSIPTIIAAVLSFFAASISSAGGIGGGGLFLSIMTIIAGLEMKTASSFSAFMVTGVSFANVGCNLFLRNPKSRDKTLIDFDLALTIQPCLLLGVSIGVICNRMFPNWLVLFLFAVFLAWSTMKTCKKGVSYWNLESERAKIKSPRDVDGIEVARSPLLSEEREDVRQRGMIRFPWMKLGVLVIIWLLFFSINLFRGNKYGQGIISIKPCGALYWFLSSLQIPLTIFFTLCIYFSDNVQSNHTSHSNQNSEQETGVGGRQNKLMLPVMALLAGVLGGLFGIGGGMLISPLLLQIGIAPEVTAATCSFMVLFSSSMSAIQYLLLGMEHAGTAAIFALVCFVASLVGLMVVKKVIAKYGRASIIVFAVGIVMALSTVLMTTHGAFNVWNDFVSGRYMGFKLPC
What are the official names of this protein?
Sulfite exporter TauE/SafE family protein 1.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RNFB_VIBVU
Sequence: MTTIMIAVLAIALLATLFGAILGFASIRFKVEADPIVDQIDAILPQTQCGQCGYPGCRPYAEAIANGDSINKCPPGGQATIEKLADLMGVEAEESAHDLEGKVKKVAFIHEDMCIGCTKCIQACPVDAIVGGTKALHTVIKDECTGCDLCVAPCPTDCIEMIPLETTTETWKWQLNAIPVVNISEANPNSATSRDQNN
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PFDA_METTP
Sequence: MSGKPQSPENQARQLIVAYQQYQAEAESLVRELGLIQMTAEGLDKAISAIGALSKAAEGQEMLVPIGSGSFAYAKLSSADRVVVNVGGGVSIEKPAEEAMEMLRARRSAISESSKKINEALAKIEQEMARIQAALERLERELQKQGGSEGFVQ
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_PROA2
Sequence: MPPINIVILIPARLNSSRLPNKMLADIEGAPLIVRTWQQAQQSSLTRQVVIATDSEEIAGVMKACGADVVMTSPDARCGTERIAEAAENIDADVFVNLQGDEPLIDPGNIDLVIKPFLQENPPDCSTLVYRLLAEDYAALHDPNIVKVVMDSQSNALYFSRSPLPYQRETYAATRCFRHIGIYAFRAGVLRMFSEHGPSMLEEAESLEQLRLVENGYSIRCVETDVDMPGVNTHEDLELVRRLYRSRRS
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIA_MYCBO
Sequence: MLSVPHLDRDFDYLVPAEHSDDAQPGVRVRVRFHGRLVDGFVLERRSDSDHHGKLGWLDRVVSPEPVLTTEIRRLVDAVAARYAGTRQDVLRLAVPARHARVEREITTAPGRPVVAPVDPSGWAAYGRGRQFLAALADSRAARAVWQALPGELWADRFAEAAAQTVRAGRTVLAIVPDQRDLDTLWQAATALVDEHSVVALSAGLGPEARYRRWLAALRGSARLVIGTRSAVFAPLSELGLVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAHALVRSGWAHDVVAPRPEVRARSPRVVALDDSGYDDARDPAARTARLPSIALRAARSALQSGAPVLVQVPRRGYIPSLACGRCRAIARCRSCTGPLSLQGAGSPGAVCRWCGRVDPTLRCVRCGSDVVRAVVVGARRTAEELGRAFPGTAVITSAGDTLVPQLDAGPALVVATPGAEPRAPGGYGAALLLDSWALLGRQDLRAAEDALWRWMTAAALVRPRGAGGVVTVVAESSIPTVQSLIRWDPVGHAEAELAARTEVGLPPSVHIAALDGPAGTVTALLEAARLPDPDRLQADLLGPVDLPPGVRRPAGIPADAPVIRMLLRVCREQGLELAASLRRGIGVLSARQTRQTRSLVRVQIDPLHIG
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Probable primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: BETI_BURCH
Sequence: MPKVGMREIRRAQLIDATLRSIDEAGLPGTTLASVAQRANISTGIVSHYFGDKDGLLEATMRHVLRDLWSATTRRRVAARKDPRSRLRAVVAANFDDTQVSAPVMKTWLAFWSQSMHDPMLKRLQHVNTRRLHSNLCAEFAKALPLAKAREAASGLAALIDGLWLRGALAGGPIDTRAALKLAHDYIDLLLASD
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: NUON_ECOK1
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLVGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ELDP1_LOTGI
Sequence: MMHTFLRRLCVVALCLGYIKASADFDCRRTSQSCVTGTCNDVNGDCDCPTDANGVATHRNADCGLEIAKVVPTALCGPPCLNGGECYEPTVGTYMCMCPEAFYGNKCENPRKKVECSGTEITINYMPIPTFSGDIFILDNRNTPECAFTEANGMYTATFTYQQCGVTTTNDQPNAGDTSYEISAAVRFNANIERATDMKLTAKCVIDGTGQSNLNDNIGTVSVDQRTDLTEETALTEYQPVSFQLQGKNGNPMPVPVNLGDELRIYIPLADTGRYTKLKITELQTNNGMVEQDLVMETLIFNGCLTDIGEALVTGDISSDPAIPAIIINFMAFRLRGSPQVKFDARVQVCEGTDTSCDSVVCPSPPQSVPSNPQNIPPANPQNIPPANPQNIPPANPQISPSSSQRKRRAAPDNEVILHETLTVLDPRSNEKLRLPHNKSDIKSQQNADPQQCLQSTEIMVMVIVLIVAVVLLLVITTCLAVKFMKQRAAQVKIYNPDMPTGNNTVRIPRAAC
What are the official names of this protein?
EGF-like domain-containing protein 1, Uncharacterized shell protein 17, LUSP-17.
Protein: SYE_BURM7
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDLERSTEASVDAILEGMAWLGLDYDEGPYYQMQRMDRYREVLAQMLEKDLVYPCYMSTEELDALRERQRAAGEKPRYDGTWRPEPGKVLPEPPAGVTPVLRFRNPLTGSVVWDDAVKGRVEISNEELDDLVIARPDGTPTYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQGEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHNKLNWLNNHYIKEADDARLAELAKPFFAALGIDADTIARGPDLVGVMGLMKDRASTVKEIAENSTMFYRSPAPDAQALAQHVTDAVRPALAEFAAALKTAEWTKEAIAAALKAVLGAHKLKMPQLAMPVRLLVAGTTHTPSIDAVLLLFGRDVVVSRLAAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_DESHD
Sequence: MKALEWMGDSLKILDQTRLPVEIKYRMAATYEEVAEAIEKMEVRGAPAIGAAAAYGYALGAIGYSGELADLPAHMEKVQHRLAETRPTAVNLFWALRRMEDRLRDQHEAKELAEIRQALVAEAENIAEDDRRVNRLIGEHGNAIVTAEANILTHCNAGALATVEYGTALGVIRAAQQAGKKVHVYAGETRPFLQGARLTALELMNDHIPVTLIADNMAGFLMQQGNIDLVIVGADRIAANGDTANKIGTYSLAVLAHAHGIPFYVAAPTSTIDLKVPSGQDIPIEERNPKELREVFGVQVAPPEVPVYNPAFDVTPAKLITGIITEKGIVTSPYSVNLLKMMVRS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: ATPG_AZOVD
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQLRMAASRPYAERIRQVIGHLAKANPEYKHPFMVERPVKRVGYILVSTDRGLCGGLNINLFKALIKSMKEWHDKGVEADFCVIGNKGASFFRSYGGNVVAAIGNLGEEPSINSLIGSIKVMLDAFHEGRVDRLYLASNKFINTMTQKPVVEQLLPLAASDDEGVQKGTWDYLYEPNAQQLLDALLVRYMESQVYQAVVENGAAEQAARMIAMKNATDNAGELISDLQLVYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLD16_BOVIN
Sequence: MGPGLAASHVSFPDSLLAKMRDLLQYVACFFAFFSAGFLVVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHSLKLVVTRALMITADILAGFGFITLLLGLDCVKFLPDEPYIKVRISFVAGTTLLIAGAPGIIGSVWYAVDVYVERSSLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAILTCCLYLFKDVGPERSYPYSTRKAYSTTAVSMPRSHAIPRTQTAKMYAVDTRV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.  Involved in paracellular magnesium reabsorption.  Required for a selective paracellular conductance.  May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients.  Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors (By similarity).
What are the official names of this protein?
Claudin-16, CL-16.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: HIS7_SACD2
Sequence: MADRKAQVSRDTLETQISVELNLDGTGTGKFNTGVPFLEHMMDQIARHGFIDLDVTCKGDTYIDDHHSVEDIGITIGQAMAKAVGDKRGIRRYGHAYVPLDEALSRVVIDFSGRPGLIMNIPFTQKRIGKFDTELFWEFFQGFVNHAGVTLHVDCLRGENAHHQIETVFKAFGRSLRMALERDERLGDAMPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON2_HYDS0
Sequence: MKALYPDIITTVGIIFLIILELFLPSFDLIGFLGFLISFISGVLAIKYSLAGYRFNEWLLDINAFSLLLKGVMYILTSFVIFSSVSFFKSKKTFVENVYTFLLISLGLSIMVSSKNLAVILAGLELASISMYISVGMLRDDYISKEASFKYLVLGSMTTAFFGIGSAFYIGATSHLDIISVSVNHNTAFALASLFLFVAFALKVSAAPFHFWTPDAYEGAPTSNTAFISTVPKIGFYAVLFLLASYIFPVTNNFSYIVGIVGVISMFWGNLVAYAQNSAKRMLAYSSIGHAGYFLIGFSRYNPLSVSSTIFYVIVYAFATAGAFLVLSILEKNQSWTHDMSNYRALYKRSPFLATALALFLFALIGIPPFATFVGKLGIFLGLVNSNAWFFAILFVIGSIIAAGYYLKLIVYMFFKEPATKDNMSLSLNLFDTIGISAFLIIVFFFGIFPNILFDIILKDMFHG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 2, NADH dehydrogenase I subunit N 2, NDH-1 subunit N 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSRAB_HAEIN
Sequence: MKLSKTFLFITALCCATPTLAIQNSTSSSGEQKMAMENTQNIREIYLAGGCFWGMEAYMERIHGVKDAISGYANGNTEKTSYQMIGLTDHAETVKVTYDANQISLDKLLKYYFKVIDPTSVNKQGNDRGRQYRTGIYYQDGADKAVIGQALAQLQTKYKKPVQIEVQPLKNYIVAEEYHQDYLKKNPNGYCHIDITKADEPVIDEKDYPKPSDAELKAKLTPLQYSVTQNKHTERSFSNEYWDNFQPGIYVDITTGEPVFSSNDKFESGCGWPSFTKPIIKDVVHYETDNSFNMQRTEVLSRAGNAHLGHVFDDGPKDKGGLRYCINSASIKFIPLAEMEKAGYGYLIQSIKK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: MPIP2_XENLA
Sequence: MYILLTLLTKSTMESSCDNFEGLEHYYYTDAEPSSKCNKFQASGGSGVVMAESHIMSSEAPPKSNPGLNIRTNCRMILNLLREKDCSVTFSPEQPLTPVTDLAVGFSNLSTFSGETPKRCLDLSNLGDETAPLPTESPDRMSSGKLESPKTQFVQFGGLFTPDLAWKAKKCPKRNMNSVLPHLLCSTPSFKKASGGQRSLSNKENEGELFKNPNCKPVALLLPQEVVDSQLSPTPENKVDISLEEDCEMNILGSPISADPPCLDGAHDDIKMQNLDGFADFFSVDEEEMENPPGAVGNLSCSMAILLSGPLLNQDVEISNVNNISLNRSRLYRSPSMPEKLDRPMLKRPVRPLDSETPVRVKRRRSTSSPLQPEEENCQPQRRGTSLKKTLSLCDVDISTVLDEDCGHRQLIGDFSKVYALPTVTGRHQDLRYITGETLAALMHGDFNSLVEKFFIIDCRYPYEYDGGHIKSAFNLHRQEEVTDYFLQQPLTPLMVQKRLIIIFHCEFSSERGPKMCRFLREEDRASNDYPSLYYPELYLLKGGYKDFFPEYKELCEPQSYCPMHHQDFREDLLKFRTKCKTSVGDRKRREQVARLMKL
What is the function of this protein?
This protein functions as a dosage-dependent inducer in mitotic control.  It is a tyrosine protein phosphatase required for progression of the cell cycle.  It may directly dephosphorylate p34(cdc2) and activate the p34(cdc2) kinase activity.
What are the official names of this protein?
M-phase inducer phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
Protein: ISPE_BACLD
Sequence: MRILEKAPAKINLSLDVRHKRPDGYHEVEMVMTTIDLADRVELTELAEDKVTVSSHNRFVPDDQRNLAYQAAMLMKERYGIKKGVSIFITKVIPVAAGLAGGSSDAAAVFRGLNRLWDLKLSMNELAELGAEIGSDVSFCVHGGTALATGRGEKIRHIETPPHCWVVLAKPTIGVSTAEVYKQLKVDEIEHPDVQGMIAAIEEKNFQKMCDKLGNVLESVTLNMHPEVAMIKNQMKRFGADAVLMSGSGPTVFGLVQYESKVQRIYNGLRGFCDQVYAVRMIGEQNELD
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: AIM3_ZYGRC
Sequence: MSDFWEKNKGSITSGLKKTGKVGLSGTKYVAKTGYQAGKKNWGGNKKDKQNKKQGEEDVDDELDEEPAHHASYPPRVVDPSYFPPPPSRTNPSQNVAGEHMPRQTYPAQPSIQQPVYQQPVYQQSAYPAQVPQQAPQPAPQQAQYVIQQPPPPPRNPGYQQLPSQQAYEEPAQYSYQQPPPQSGFQQPPQAGYQPTQQTYQPTQQTYQPTQQTYQRPAQPVPPPPSNQSPQQVIQQPPPPPRSGYQQSPPPQVGYQQPPPPPRAGYQQSPPPQFDYQQPPVQQHAHSGPLPPSRPSDQYLTPIQTQSTVHSQTRPYDLTAPHVKQRLEMQSVDLTNLPPPPTHRDRSSPPKSRESSPAGQSQKVHSGSTPPPTYESSQKDIESSMSSSSVTPSTQPALASRPSSISSQSRSNVPPPMPPKPNEPGMVDVSSFPPPPRPRPTPSMERETALKAQDPSTGPTPRGRLAGSKPPPPPVKPKPRNLAAGSGSGSGSLGSGNHTPLASVDSISQELSKVQLKKTNSKYTQEPTSSKLPPPAVPRKNFTPDKQGTPLPPNKNASLKSPTDQQDVNPFERYLKSAVPAENDRLHKPM
What are the official names of this protein?
Altered inheritance of mitochondria protein 3.
What is the protein family that this protein belongs to?
Belongs to the AIM3 family.
What are the subcellular locations of this protein?
Membrane raft; Peripheral membrane protein. Note=Localizes within detergent-insoluble glycolipid-enriched membranes.