PharMolix/UniProtQA huggingface dataset:
Protein: FABG_SYNY3
Sequence: MTALTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFIATDMTENLNAEPILQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQTFNVDGGMVMF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (Probable).  Is capable of reducing acetoacetyl-CoA, but less well than its paralog PhaB (PubMed:26358291).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: GCSP_TERTT
Sequence: MPNTDSLNNLFASDEFISRHIGPDQNQVEKMLATLEVDSLDALIEKTVPATIREAQPLPLAEPVAEHTALEELKSLAAKNDVFTSYIGLGYHPTRVPNVILRNVLENPGWYTAYTPYQPEIAQGRLEGLLNFQQMITDLTGMEMANASMLDEATAAAEAMAMAKRVGRKNSSNCFFIDKNCYPQTIAVMRTRAEHFGFDIIVDAPEKALAGEDYFGAILQYPGADGGIGDIESWIKTIQSKDALAIVAADIMSLVLLRSPGDMGADIVIGCNQRFGIPMGFGGPHAAFFAFKEKHKRSTPGRIIGVSVDSRGKQALRMAMQTREQHIRREKANSNICTSQVLLAVMSAFYAMYHGAEGVDRIARRIHILTKMLSEGLISLGYKLRHTTFFDTLCIEVGDQQKPLLDRAQHARINLCAMGSGALSISLSECTTLDDLTALIAVFAGGESPLDMPSLEAKAQQKAVLSENLLRDGRALQHEIFSQYHSETEMLRYLKRLESRDIALNHAMIPLGSCTMKLNATAEMIPVTWPEFGNMHPFAPISQAAGYAEMFNQLQHMLAACTGYDAISLQPNAGSQGEYAGLLTIKKYFEAKGEVRSICLIPQSAHGTNPASAQMASMKVVVVNCDDDGNVDIADLDAKIAQHGENIAAIMVTYPSTHGVFEENITQICDKIHAVGAQVYIDGANMNALVGIASPGHFGGDVSHLNLHKTFCIPHGGGGPGMGPIGVKDHLAPYLAAHPLQEIPGTVAANGTVSAAPWGSASILPISWMYIRMMGAKGMKMASEYAILNANYIAKRLKNHFPILYSGKHGFVAHECLLDLRPLKEASGVSEEDIAKRLMDFGFHAPTMSFPVAGTLMIEPTESENQFELDRFCDAMIQIREEIRKIEQGELPADDNPLVNAPHTLDDVCNSEWNRSYTRDQACRPLDYLKHHKVWPTVNRIDNVYGDRNLICSCPGVDDYR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: FENR_GEOTN
Sequence: MSVREDRNVYDVTVIGGGPTGMFAAFYGGLRQMNVKIIESLPQLGGQLAALYPEKYIYDIAGFPKVRAQELVDQLKEQLSRFSPTICLNQSVEMLEKQEDGTFKLTTDKEIHYSKTVIITAGNGAFQPRRLEIDSASQYEGKNLHYFISDLQQFAGKRVLVCGGGDSAVDWSLMLEPIAASVTIVHRRDKFRAHEHSVEQLMNSRVQVKTPYVPAELIGDEQGIRQVVLEHVKEGAKETIDVDAVIVNYGFISSLGPIKNWGLDIEKNSIKVNSRMETNIPGVYAAGDICTYDGKIKLIACGFGEAPIAISSAKTYIDPTARMQPAHSSSLF
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: CYSH_XANCP
Sequence: MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFPETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRAQTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHEDI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_ECOK1
Sequence: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: MAL31_YEAST
Sequence: MKGLSSLINRKKDRNDSHLDEIENGVNATEFNSIEMEEQGKKSDFDLSHLEYGPGSLIPNDNNEEVPDLLDEAMQDAKEADESERGMPLMTALKTYPKAAAWSLLVSTTLIQEGYDTAILGAFYALPVFQKKYGSLNSNTGDYEISVSWQIGLCLCYMAGEIVGLQMTGPSVDYMGNRYTLIMALFFLAAFIFILYFCKSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWAFGQLFAAGIMKNSQNKYANSELGYKLPFALQWIWPLPLAVGIFFAPESPWWLVKKGRIDQARRSLERTLSGKGPEKELLVSMELDKIKTTIEKEQKMSDEGTYWDCVKDGINRRRTRIACLCWIGQCSCGASLIGYSTYFYEKAGVSTDTAFTFSIIQYCLGIAATFISWWASKYCGRFDLYAFGLAFQAIMFFIIGGLGCSDTHGAKMGSGALLMVVAFFYNLGIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVVTVLIMYQLNSEKWNWGAKSGFFWGGFCLATLAWAVVDLPETAGRTFIEINELFRLGVPARKFKSTKVDPFAAAKAAAAEINVKDPKEDLETSVVDEGRNTSSVVNK
What is the function of this protein?
High-affinity uptake of maltose and maltotriose.  Also transports turanose but not alpha-methylglucoside, melezitose or trehalose.
What are the official names of this protein?
Maltose permease MAL31, Maltose transport protein MAL31.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VT4_SHEVN
Sequence: MSSLTFFIFCLQLFIFTSTVSGISIKRCTEEENNTWEIEVGLCIQTENFRAIKTGCYKIQGPGGLLTEGNGFKIFAHDDCSKEKTQNNFILDSVNEAVYALGKYVYMEISTSNITTLNSLPQCAKRISLSISCDQVTTEMKSYVESVSFKDYDLEFVITTDISCVKHVSSSVIVRNECEKKYISTGKKIFGFNNKIDCSAVKFSEHVNYLKTCSVGKFDRKKYYEHQHNYIKKIFHHNEL
What are the official names of this protein?
T4 protein.
What is the protein family that this protein belongs to?
Belongs to the poxviruses B9 family.
Protein: FMT_MYCS2
Sequence: MRLVFAGTPEPALPSLRRLIESPRHDVVAVLTRPDAAAGRRGKPRPSPVAQLALEHGIPLLRPDRPNSDEFVAELTELAPDCCAVVAYGALLSQRLLAVPRHGWINLHFSLLPAWRGAAPVQAAIAAGDTVTGATTFQIEPALDSGPVYGVVTETVRDTDTAGDLLERLSDSGAELLERTIDGIADGSLTAVPQPSEGITVAPKITVESARVRWDLPAHVVDRRIRAVTPNPGAWTMIGELRVKVGPVTVDQAAEADGPLAPGEIRVGRNSVHVGTGSHPVRLGQIQPPGKKLMNAADWARGARLEEPVSAS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PRO_ADEG1
Sequence: MSGTTETQLRDLLSSMHLRHRFLGVFDKSFPGFLDPHVPASAIVNTGSRASGGMHWIGFAFDPAAGRCYMFDPFGWSDQKLWELYRVKYNAFMRRTGLRQPDRCFTLVRSTEAVQCPCSAACGLFSALFIVSFDRYRSKPMDGNPVIDTVVGVKHENMNSPPYRDILHRNQERTYYWWTKNSAYFRAHQEELRRETALNALPENHV
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: DXS_ALKOO
Sequence: MYKYLMEINSIEDFKKLNSNEIKVLAEEIRHFLIESVSKTGGHLASNLGVVELTLALHQAFNSPEDKIIWDVGHQAYVHKILTGRRDQFSTLRQYKGLSGFPKRYESEHDQFDTGHSSTSISAAMGLATARDLNKDKYKVIAVIGDGAMTGGMAFEALNHIGQSQKDIIVILNDNEMSISPNVGGLSNYLNKIRTAPIYSKVKDDVEYLISNIPAIGKSVMKTAEKAKDSIKYFFVPGVLFEELGFTYIGPVDGHNYHSLYDVMNRTKNIKGPVLLHVMTTKGKGYTLAEKHPDKYHGVNSFHIETGEPISCNENLSYSEIAGKTLVECAAEDEKIVAITAAMPSGTGLNNFAKKHPERFFDVGIAEQHAATFAAGLAANGFKPFFAVYSTFFQRAYDQVIHDACIQDLPVTYLIDRAGLVGNDGETHHGSLDISFLSCIPNLTFMAPKDGIELSEMVRFAAKHNGPVAIRYPRGHSNMDSQENFSPLALGKGEITYHSGNDVLILALGTFNKMGLEICKDLEENNIFSTLMNPRFIKPMDEELIVEMVQKHKIIYTIEDNSKIGGFGTLVQVLLNDNQILKPVKVCALPDRFIEHGNVEDLYEELGLTKKQIVDQIKKEFSDL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TRPA_ALIF1
Sequence: MDRYQALFAQLEKKNQGAFVPFVTIGDPNPELSYDIMETLIEAGADALELGIPFSDPLADGPTIQGANIRALDSKTTPAICFELITKIRSKYPDTPIGLLVYANLVFANGIDNFYTKCQQAGVDSVLIADVPTNESQEFRESAIEHGIHPIFIAPPSASPETLETVAKLGGGYTYLLSRAGVTGAETKAGMPVAQLLERLNQYDAPPAILGFGISEPAQVEEAVKAGAAGAISGSATVKLIEQHQANPEALLKALADFTSSMKAATQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RSMH_DESAH
Sequence: MKFEHRSVMPREVRDGLDLKPGETCVDCTLGGSGHAVTSLAAVLPNGRLIGIDQDLDAIENAHRVFADDMANVSIFHDNFSHLPAILDSLGIKGVDGILLDLGLSLHQLRKGQRGFSFKGDEPLDMRMDMRTALTAADLVNTLEERALVDIFFKYGEEKMSRKIARAIVRQRASAPITRNCELAEIVRAAIPAKIVHQQKIHPATRVFQALRISVNRELEQLERFLETFVDFLNPGGRICIISFHSLEDRMVKRRFRALEQGCTCPRDFPECVCGFKPRLKSVTKRAVMPTPEEIEINPMARSARLRVAWRV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLE_KLEP7
Sequence: MNKDNVKLAIAPIGWTNDDMPELGSENTFQQIVSEMALAGFTGSEVGSKYPRDPAVLKPMLDIRGIQICNAWFSTFFANGQREKTIDEFVNHMNFLHAMGAKVIGCSEQSGSIQGLDKPILGDAKPCFSDEEWQRVAEGYNTLGRLAAEKGMQVCLHHHMGTGIQTTAEIDKFMSLVDERVFLLFDTGHAWYSEGGEAPMLAILKKYLPRINHVHLKDVRPPVIDQVRRDGLSFLDGVKKGTFTVPGDGVIDFRPVFKLLDDFGYKGWMVVEAEQDPALANPFEYAVKARKYIRETAGI
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: DEOD_LISMO
Sequence: MSVHIEAKQGEIAETILLPGDPLRAKYIAETFLEDVVLFNQVRGMLGFTGTYKGEKVSVMGTGMGIPSISIYVNELIQSYDVKNLIRVGTMGGIQADVKVRDVVIAQAASTDSQINRNTFAGVDFAPVADFSLLKKAYDAGIEKGLSLKVGNVFSADRFYNDQLDKQQLADYGVLGIEMEAAALYTLAQKYGRRALAILTVSDHIFTGEETSAEERQTTFNDMIVVALEAAIK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: SL1_SISCA
Sequence: MGRFIFMSFGLLVVFLSLSGTGADCPSDWSSYEGHCYRVFQQEMTWEAAEQFCAQQRKESHLVSFHSSEEVDFLVSITYPILKADLVWIGLRDIWNECRLEWTDGTKVDYKEWSEEPECIVSKTTDNQWISRPCSRTYSFVCKFQA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 1, C-type lectin isoform 1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAP_BOVIN
Sequence: MRLHHLLLALLFLVLSAWSGFTQGVGNPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
What is the function of this protein?
Has antibacterial activity in vitro against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, and Pseudomonas aeruginosa.  In addition, the peptide is active against Candida albicans, indicating a broad spectrum of activity.
What are the official names of this protein?
Tracheal antimicrobial peptide, TAP.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AXFA_PRER2
Sequence: MYQSTLKTILLASALLILPASMSAQKRKAAPKKAATEQVGKPDPNFYIFLCFGQSNMEGNARPEAQDLTSPGPRFLLMPAVDFPEKGRKMGEWCEASAPLCRPNTGLTPADWFGRTLVASLPENIKIGVIHVAIGGIDIKGFLPDSIQNYLKVAPNWMKGMLAAYDNNPYERLVTLAKKAQKDGVIKGILMHQGETNTGDPKWAGMVKQVYDNLCGDLNLKPEEVNLYAGNIVQADGKGVCIGCKKQIDELPLTLHTSQVISSDGCTNGPDRLHFDAAGYRELGCRYGEAVARHLGYEPKRPYIEMPKQIEVPADAFIAETTVPGNEFPKVDKEGRAYFRIAAPEARKVVLDICNKKYDMQRDGKGNFMAVTDPLPVGFHYYFLNINGVNFIDPSTETFFGCNRESGGIEIPEGSEGDYYRPQQGVPAGQVRSIYYYSNEQQTWRHAMVYTPAEYELAKNAKKRYPVLYLQHGMGEDETGWSKQGHMQHIMDNAIAKGEAVPMIVVMESGDIKAPFGGGNNQAGRSAYGASFYPVLLNDLIPYIDSNYRTKSDRENRAMAGLSWGGHQTFDVVLTNLDKFAWLGTFSGAIFGLDVKTAYDGVFANADEFNKKIHYMYMNWGEEDFIKSGDIVKQLRELGIKVDSNESKGTAHEWLTWRRGLNEFIPHLFKK
What is the function of this protein?
Involved in degradation of plant cell wall polysaccharides.  Bifunctional esterase that possesses both acetyl esterase and ferulic acid esterase activities.  Has deacetylase activity towards acetylated xylo-oligosaccharides smaller than xylo-heptaose, as well as from glucose-pentaacetate.  Is also able to release ferulic acid from methylferulate, and from the more natural substrates wheat bran, corn fiber, and XOS(FA,Ac), a corn fiber-derived substrate enriched in O-acetyl and ferulic acid esters.
What are the official names of this protein?
Carbohydrate acetyl esterase/feruloyl esterase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the carbohydrate esterase 6 family.
Protein: PA2B_AUSSU
Sequence: MYPAHLLVLLAVCVSLLGASDIPPQPLNLVQFSNMIQCANHGRRPTSNYMDYGCYCGKGGSGTPVDELDRCCKIHDDCYGEAEKSQKCAPYWTWYTWKCGSDGPQCDDSKTGCQRFVCDCDATAAKCFAKAPYNKENYNIKTRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 S2-22, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AUR25_RANAE
Sequence: MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVGAFGSLGKRNDLE
What is the function of this protein?
Amphipathic alpha-helical antimicrobial peptide with moderate to potent activity against Gram-positive bacteria, Gram-negative bacteria and fungi (PubMed:10951191, PubMed:19056250, PubMed:23841919, PubMed:24728560, PubMed:31358802).  Shows also a weak activity against biofilm of both Gram-positive and Gram-negative bacteria (PubMed:19056250).  Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191, PubMed:23841919).  Kills fungi via membranolytic action (PubMed:24728560).  Enhanced sterol levels in lipid composition membranes reduce interaction of this peptide with membranes, having a protective effect against the lytic ability of the peptide (PubMed:24728560).  Shows anticancer activity (PubMed:10951191).
What are the official names of this protein?
Aurein-2.5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Contact and insertion into membrane begin at the N-terminus.
Protein: S6A19_HUMAN
Sequence: MVRLVLPNPGLDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTASMNGDLKY
What is the function of this protein?
Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells (PubMed:15286787, PubMed:15286788, PubMed:18424768, PubMed:18484095, PubMed:19185582, PubMed:26240152).  This uptake is sodium-dependent and chloride-independent (PubMed:15286787, PubMed:19185582, PubMed:15286788).  Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity (PubMed:19185582, PubMed:18424768).
What are the official names of this protein?
Sodium-dependent neutral amino acid transporter B(0)AT1, Solute carrier family 6 member 19, System B(0) neutral amino acid transporter AT1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A19 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Colocalizes with ACE2 on the apical membrane of cells lining villi of the jejunum, ileum and on kidney proximal tubules.
Protein: DLTC_STRPQ
Sequence: MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBP1_RAT
Sequence: MVWEVKTNQRPHAVQRLLLVMDERATGVSDSLELLQCNENVPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRPSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSAKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKESKKEWQDVEDFARAASCDEEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGTGQEFAGSEFSKSCGSPGSSQLSSSSLYTKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH
What is the function of this protein?
Transcriptional repressor that binds to the promoter region of target genes.  Plays a role in the regulation of the cell cycle and of the Wnt pathway.  Binds preferentially to the sequence 5'-TTCATTCATTCA-3'.  Binding to the histone H1. 0 promoter is enhanced by interaction with RB1.  Disrupts the interaction between DNA and TCF4 (By similarity).
What are the official names of this protein?
HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRC_SYNP2
Sequence: MEKITLTRPDDWHLHLRDGEALKAVLPDTVRQFARAIVMPNLKPPVRTVAEAAAYHDRILAAIPPGRTFEPLMTLYLTDNTSPAEIQAAKESGFVKAVKYYPAGATTNSDLGVTDIRKCDAVFEAMQTVDLPLLLHGEVTDHRVDVFDREKVFIETYLRPLKERFPQLRIVLEHITTKDAVEFVLASDEKVAATITPQHLLFNRNSIFQGGIRPHFYCLPILKRETHREALLEAATSGNPKFFLGTDSAPHGRDRKESDCGCAGCYSALHALELYATVFEAADALDKLEGFASFYGPDFYQLPRNTEKITLTKTPWQIPDALPFPESSLVPLWAGQELSWKFAPVA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: URE3_PSEA7
Sequence: MDLSPREKDKLLIFTAGLLAERRLARGLKLNYPEAVALISAALLEGARDGRSVAELMHYGTTLLSREQVMEGVPEMIPDIQVEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTP_YERE8
Sequence: MKTRHWSVLSLLALPALSQAEAITGEVHRQPLNIEAIVMFVLFVGATLYITYWASKRTRSRGDYYTAGGRITGFQNGLAIAGDFMSAASFLGISALVYTSGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLKQRPIRTLSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHVAVVLVGILMVMYVLFGGMLATTWVQIIKAVLLLAGASFMALMVMKSVNFNFNTLFSEAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVGPNPAFKDAAGALLGGNNMAAVHLADAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELKVSKITVVVLGFVAIGLGILFEKQNIAFMVGLAFSIAASCNFPIIFISMYWEKLTTRGAMIGGWLGLLTAVILMILGPTIWVTILGHAKPIYPYEYPALFSMIVAFVGIWFFSITDNSEEGQQERLRFKAQFVRSQTGLGASQSSSH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU3C_CAPBU
Sequence: MFLLYEYDIFWAFLIISSAIPVLAFLISGVLSPIRKGPEKLSSYESGIDPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEAFIFVLILILGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.