PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_I01A0
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITMERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRIVPRGQLSTRGVQIASNENMDTMDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESAKPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFEN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATF3_RAT
Sequence: MMLQHPGQVSASEVSATAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTINNRPLEMSVTKSEVAPEEDERKRRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
What is the function of this protein?
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters.  Represses transcription from promoters with ATF sites (By similarity).  It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, Liver regeneration factor 1, LRF-1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAIP1_HUMAN
Sequence: MSDGFDRAPGAGRGRSRGLGRGGGGPEGGGFPNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQTRPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDGCEDYPTLSEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSGNFRQLLLQRCRTEYEVKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNWGRVHATSTYREATPENDPNYFMNEPTFYTSDGVPFTAADPDYQEKYQELLEREDFFPDYEENGTDLSGAGDPYLDDIDDEMDPEIEEAYEKFCLESERKRKQ
What is the function of this protein?
(Microbial infection) Upon interaction with SARS coronavirus SARS-CoV NSP3 protein, plays an important role in viral protein synthesis.
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_MARN8
Sequence: MTINRWHLLVSGKVQGVYYRASTEQKARELGLTGWVRNLPDGRVEIVAEGEPLQLKALHEWCHEGPERAVVDEVAAQELPATQEFTDFRTTH
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: 1A11_PRUMU
Sequence: MGSSSATANRFLLSKIATSEGHGENSPYFDGWKAYDRNPFHPTKNPEGVIQMGLAENQLSFDSIEDWIKKNPKASICTPEGVEEFKNVAIFQDYHGFPEFRKAVAMFMSKARGGRVTFDPNRVVMSGGATGANELVMFCLADPGDAFLVPSPYYPAFFRDLGWRTGVQIVPVDCDSSNNFKITKEALEAAYEKAQKNNINVKGLIITNPSNPLGTTLDRNTLESLVEFINQKNIHLVCDEIYAATVFSSPTFTCISEVIQNMNCNPNLIHIVYSLSKDMGLPGLRVGIVYSYNDDVVNIGRKMSSFGLVSSQTQHMLPSMLLDEEFVARFLETSPKRLAKRHGVFTKGLEEVGINCLKSNAGLFCWMDLRRLLEDQTFDGEMVLWRVIVNEVGPNVSPGSSFKCVEPGWFRVCFANMDDETLEVALKRIRTFVRQGKKAQDQVVQVKSPKRWKSNLRLSFSSSSTRRFDQESVNVLSPHMMSPHSPLVRAKT
What is the function of this protein?
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase 1, ACC synthase 1, S-adenosyl-L-methionine methylthioadenosine-lyase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: KS6A6_MOUSE
Sequence: MLPFAPVEDPWDQEDMEVFGSTSSSEPQVVFTMKNAATVMREHERKEVNDLKMVDEPMEEGEPVSCRREELVKEVPITQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRAHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGNAAQFSEAYELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHPNIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCFSEQEASNVLYVITKTVECLHSQGVVHRDLKPSNILYMDESAHPDSIKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQQGYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAKDLLSHMLHMDPHQRYTAEQVLKHPWITQREQLPRHQPNSDEPPQEAVAAPYSVLARNPNRHHPILEPVTASRLAQRRNMKKRTSTGL
What is the function of this protein?
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.
What are the official names of this protein?
Ribosomal protein S6 kinase alpha-6, S6K-alpha-6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Predominantly cytosolic.
Protein: TILS_SHEON
Sequence: MTAQDLSVHIARWLDSLPLQAGSKLVLAYSGGVDSEVLAYGLSEYAKQRPDLRYQLIYVHHGLSPNADNWAKHCQARAAIYGLPVTVERVQLILGPRVSVEAEARKARYQAILPHLNPQDILLTAHHEDDQLETILLALKRGQGPKGLAAMGQIQPLSLADKGSCLQVRPLLDISREMIETFAQTRQLVHIEDESNQDDKYDRNFLRLEIIPRLKARWPSIATTASRSAQLCAEQQAIVETEVSERLPKLLVKAPVTEQTVLKLSELAAQPIEWQGILLRGFIESQEFSLPSYVQLQQMLQQLIHAKEDAKVHIRINDCVLRRFAGMLYLDSGETLSTALHITARDLHQEILTLLTQASAMVEDKIVPFALVTTGPRLRLPKADEVVSLGYGLPGQFRCQPHFRDKGRELKKLWQECAVPPWLRAEVGFLFYNDKLVMAFGLWVEKAFCAQGDEIGLSYLIANP
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_EHRCR
Sequence: MIFDEDSNSIAQDSGYMAVGNAYSNGVSYISMSDHWSKLTKPSSIKVVPSGASPNKADLIIEPLESGFALTLGNALRRVMMSSLRGFAVYGVEIENVLHEFTSISGVREDVTDILLNISMMRVKLSGMNSKVLSLKVKGPCEVRSGMIPDTDDCIILNKDLLICTLDQGVDFNIKMYVNAGKGYVPAVKRKSVNKLGDIPINFIATNALYSPIKKASFKVESSRIGQFTDYDRLIMSVETDGSILPDEAVALAARILQDQFQPFINFDETDEPHKKVDAKDTLPYDSNLLRKVDELELSVRSYNCLKNDNITYIGDLVQKTESDMLRTPNFGRKSLNEINELLASMNLHLGMKIANWPPESIESLSKQYSEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TPMT_PSEPW
Sequence: MEAAFWHQKWADNQIGFHQAQANPYLQRYWPGLGLAAGSRVLVPLCGKSLDMAWLAGQGYRVRGIELSRRAVEDFFQEQGLQAQVWQQGAFEVWCSGEVELWCGDFFALRAEDVADCVGLYDRAALIALPPQMRERYMGLLSQILPVGSGLLVTLDYEQKLLAGPPFSVADEEVRRGFAGWQVEEVEARDVIGESPKFLQAGVKRLVERVYRVQF
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSD_ECO27
Sequence: MLNQLDNLTERVRGSNKLVYRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_PROMM
Sequence: MQPTADQFTEKGWAAIVLAQQLAQQRKHQQLETEHLLLSLLQQNALAGRILEKAGVSIGNLQTAVEAHLQEQPTMQAAPDSVYLGKGVNDLLDQAEKHKQAFGDSFISIEHLLLALAGDNRCGRKLLNQAGVDAGKLKVAIDAVRGNQKVTDQNPEGTYESLEKYGRDLSAAAREGKLDPVIGRDDEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGDVPAALQNRQLITLDMGALIAGAKYRGEFEERLKAVLKEVTASEGQIVLFIDEIHTVVGAGATGGAMDASNLLKPMLARGELRCIGATTLDEHRQHIEKDPALERRFQQVLVDQPTVQDTISILRGLKERYEVHHGVRIADNALVAAAVLSSRYIADRFLPDKAIDLMDESAARLKMEITSKPEEIDEIDRKIVQLEMEKLSLGRESDSVSKERLEKLERELAELAEQQSALNAQWQQEKGAIDDLSSLKEEIERVQLQVEQAKRSYDLNKAAELEYGTLAGLQKQLSEKETALAQDGEAGDKSLLREEVTEDDIADVIAKWTGIPVAKLVQSEMEKLLGLEAELHQRVIGQEQAVQAVADAIQRSRAGLSDPNRPIASFLFLGPTGVGKTELSKALASQLFDSEAALVRIDMSEYMEKHSVSRLIGAPPGYVGYEAGGQLTEAVRRRPYAVILFDEVEKAHQDVFNVMLQILDDGRVTDGQGRTVDFTNTVLILTSNIGSQSILDLGGDDSQYREMERRVHDALHAHFRPEFLNRLDETIIFHSLRREELRQIVALQVNRLRERLCDRKLGLEISDTAADWLANAGYDPVYGARPLKRAIQRELETPIAKSILAGLYGDSQIVHVDVDVDQERLSFR
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_METNO
Sequence: MTRLDNARIVRAPRGPALTAKSWLTEAPLRMLMNNLDPDVAERPGDLVVYGGIGRAARDWASFDRIVAALKDLDEDQTLLVQSGKPVGIFRTHPDAPRVLIANSNLVPHWATWAHFHELDRKGLMMYGQMTAGSWIYIGSQGIVQGTYETFVEMGRQHYGGDLAGRWILTAGLGGMGGAQPLAATMAGASCLAVECRASSIEFRLRTGYVDVQARDLDEALALIDESCRARVPRSVALIGNAAEVFAEIQRRGVRPDCVTDQTSAHDPVNGYLPRGWSIAEWEARRESDPDGVAAAAKRSMAEQVRVMLAFHRAGVPTVDYGNNIRQMALEEGVADAFAFPGFVPAYIRPLFCRGVGPFRWCALSGDPEDIYRTDAKVKQLLPDNAHLHRWLDMARDKIRFQGLPARICWVGLGDRHRLGLAFNAMVRSGELKAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGSEAADRRLERVLWNDPATGVMRHADAGYPEAIACAREQGLVLPSLG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_FLAPJ
Sequence: MLDRLQIIKQKFDEISDLIIQPDVIADQKRYVALNQEYKGLKSLVEKRDEYVILMANIEEANEIIADGSDADMVEMAKMQLEEAKERLPELEEEIKFLLIPKDAEDAKNVMVEIRAGTGGDEASIFAGDLFRMYTKYCENRGWRTSVVDMNEGTSGGFKEVIFEVTGEDVYGTLKFEAGVHRVQRVPQTETQGRVHTSAATVMVLPEAEEFDVQIDMNDVRVDFFCSSGPGGQSVNTTKSAVRLTHIPTGLVAQCQDQKSQHKNKDKAFGVLRSRLYEQELAKKQADDAVKRTSQVSSGDRSAKIRTYNYSQGRVTDHRIGLDVFDMDGVMNGKIQKFVDELQLVNNMEKLKESEIF
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAB_ECOBW
Sequence: MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVERSEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLSWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRSPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: SH34A_XENLA
Sequence: MAAQKIRSANINGLPRCKSEGTLIDFSGVPDPSLSEVKVLSPSSLRIDNPASLENVKEVVAIKDYCPNNFTTLKFSKGEHLYVLDASGGDWWYAHNSTEMGYIPSSYVQPLNYRDSCLSDSGMIDGLLENVDEGVKELDLLGDWTDSFNQDSVKKSHNNPFLRPSVSNPFLNGPLVSQTHAADTENSVDLLLFDPLAPSHVIASETSTDMLVNLLPNTTPNKVAVAVKRDNSFFRSKRSYSLSELSVLQAKSEGPTTGSFFAGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQNPGWGQTQPVETSIVCRLDSSGGAVQLPDTNISIHVPEKHVASGETQQISLKALLDPPLELNNDKCTTVSPVLEIKLSNMDVHCPLTLELRISVALGGNASALNMVGIKCLRSDAREGPYNPVTQIYMYGDTVQVKLDNLEPVMYVVMVAQGQGIVSPSSVWEYINKKVTVGLYGPKHIHPSFKAVLAIFGHDCAPKSLLVNEVGQQANNPAPVTLQLWGKQQFVLPKPQDVQLCLFSNMTNYRVDAGDQGKIVRGFQLKLGKVSRLIFPIICQDPDQLSDFTLRVQVRDEFGGVLSQYCVQTPRPLPKTGTKSTGPRRFLKKKELGKIVLSPLAITCKYPTFQDRPVTSLKYGKLLKTVVRQSKNPYLLEYKKGDVIGLLSEEKIRLKGQLWNKEWYIGYYQGKLGLVHAKNVLVVGKVKPSFFSGPELTTGLLLEQILRPCKFLTYIYASVRTLLMENIGSWRCFADALGYGNLPLSYFCRVELESETERVASVLEKLKEECNSEGKEKKSFQKELIMALLKIDCQGLVVRLIQDFVLLTTAVEVAARWRELSEKLARVSKQQMDGYEAPHRDRNGMLDSEAMWKPAYDFLLTWSAQIGESYRDVIQELHTGLDKMRSPITKRWKHLTGTLILVNSLDILRATAFSTEAPEDCII
What is the function of this protein?
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane.  Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes.  Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation.  Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
What are the official names of this protein?
SH3 domain-binding protein 4-A.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Specifically associated with transferrin receptor- containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus (By similarity).
Protein: YFIR_ECO57
Sequence: MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTRWPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESPTFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNPDVLMLARKKNDG
What is the function of this protein?
Repressor of the cell division arrest function of DgcN.  Prevents DgcN relocation to the midcell.
What are the official names of this protein?
Protein YfiR.
What are the subcellular locations of this protein?
Periplasm.
Protein: DDX4_MACFA
Sequence: MGDEDWEAEINPHMSSYVPIFEKDRYSSGENGDNFNRTPTSSSEMDDGPSRRDHFMKSGFASGRNFGNRDAGESNKRDNTSTMGGFGVGKSFGNRGFSNSKFEDGDSSGFWRESSNDCEDNPTRNRGFSKRGGYRDGNNSEASGPSRRGGRSSFRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPALSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGISFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASCFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRGNVFASVDTRKGKSSLNTAGFSSSQAPNPVDDESWD
What is the function of this protein?
ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle.  Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: FBXW4_MOUSE
Sequence: MAEDAAEDAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDTRALGRLAQVCRWLRRFTSCDLLWRPIARASLNTGFTRLGTDLMAGIPVKERVKLSQNWRLGRCRDRILLKWRYSQMPWMQLQDASLYLSQANFILAYQFRPDGASLNRRPFRVFSGHDEDVCHFVLANSHIVSAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSTRKCVMEWEEPHDSTFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFSLTSTPLSSPVYCLRFTTRHLYAALSYNLHVLDFQNP
What is the function of this protein?
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.  Likely to be involved in key signaling pathways crucial for normal limb development.  May participate in Wnt signaling.
What are the official names of this protein?
F-box/WD repeat-containing protein 4, F-box and WD-40 domain-containing protein 4, Protein hagoromo.
Protein: Y3828_BDEBA
Sequence: MSAKSNQRGAKAPLLGSKIKLNIEKLAIGGAGVARHEGMVVFVPQAAPNEEILAEITLVKKNFMEARVVEILTASPHRREPPCPVAHTCGGCNWQHITEEEQRRQKHTLVLETIKKFNRDLEFNYLPIQPSPRVLRYRNRIQPKFKNGRFGFFARNSHQIVETMDCLITEETLTDKFAEVKAWAEKKNAKDLQRLEMYIAEEGDVRYGLITDEDDGIGFSQVNRFQNEDLLRTALDWAGDGPYKKVYDLYAGAGNFTFPLAAKYAGSEIIGVELNPKLVERARSKITDKRMTYFMSDVETYMRRASIGKDDLVVLDPPRAGASEYTMQTLAAAQPRKIIYISCHPVSLARDLNWFFAQTQKLGIKYKLDRVQTFEMFPQTDHVETIAELRVDS
What are the official names of this protein?
Uncharacterized RNA methyltransferase Bd3828.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: Y086_METJA
Sequence: MLLKSPDKSPEKILKLFDEVYSKARIFYLLRTAIDLNLFEYLSSFKTAKELAEILDADLILMEYMLKILNELDLIESKVVSERIYYKNAEITNIYLKKDSNYSIINPIYSYFENIKNWENLADILKNKSNCSNMDVDNFFPKVVRRMADECKCWELQKVLNYMAKYEEFKNAKKLLDLAGGHGLYAIGFSMLNRNLKCYVFDLPNVIEETKKFIKKYNAKNVFTITGDFYKDDIGKGYDIIFCSYNPGGKNPKIAEKVYNALNEGGLFINKQFFPDKEEGIEDYINNMEWNFSKPEGLKKGKIRYTFEGDLNLNDYLKYLEDLGFKILEVVDMSELLGLDENSSSFRKSANPSDSLRFKDNSPAKMIVAKKL
What are the official names of this protein?
Uncharacterized protein MJ0086.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: PSBA_POPDE
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEVPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CCSA_THEVB
Sequence: MDLLTLEGWLDNTAFAVLFLTMLLYWCGAAFPQWPLLTAAGRTGMAIANLCITGLLAARWIEGGYFPISNLYESLFFLCWGLTAMHFVAESISGQPLVGVVTAPVAMGITAFAALSLPPEMQQSAPLVPALKSNWLMMHVSVMMLSYATLMVGSLLAIALLVVTWGQPVNLKGSSVGTGSFRSRRPEPSLEASTGNGGTTVLTPPALQLSLQRLTLAETLDNLSYRMIGLGFPLLTIGIISGAVWANEAWGAPWSWDPKETWALIVWLVYAAYLHARMTRDWQGRKPAILATVGFGVVWVCYLGVNLLGKGLHSYGWFF
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SHU2_YEAS7
Sequence: MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKICCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSB_BORPE
Sequence: MASVNKVILVGNLGRDPEVRYSPDGAAICNVSIATTSQWKDKASGERREETEWHRVVMYNRLAEIAGEYLKKGRSVYIEGRLKTRKWQDKDTGADRYSTEIVADQMQMLGGRDSGGDSGGGYGGGYDDAPRQQRAPAQRPAAAPQRPAPQAAPAANLADMDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: PLCX3_BOVIN
Sequence: MASSQGKNELKFADWMATLPESIHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKELVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFEEGEANT
What are the official names of this protein?
PI-PLC X domain-containing protein 3.