PharMolix/UniProtQA huggingface dataset:
Protein: GCBP_THET8
Sequence: MPTFIVLSTLTDDGAETLVKNPERIKEVNQELERDFGVRVVAQYAVLGPYDFVNVVEAEDAATVARAMLHLASRGSVKTMTLEAIPVADLIARLK
What is the function of this protein?
Binds to glutamine synthetase and cystathionine beta-lyase.  May be utilized for the efficient use of nitrogen in the global nitrogen regulation of T. thermophilus.
What are the official names of this protein?
Glutamine synthetase and cystathionine beta-lyase binding protein, GCBP.
Protein: BCHB_CHLPB
Sequence: MRLAFWLYEGTALHGLSRVTNSMKNVHTVYHAPQGDDYITATYTMLERTPEFPALSISVVRGQDLARGVSRLPGTLQQVEEHYHPEVIVVAPSCSTALLQEDLSQLSMHSGVDTGKILVHDVNPFRVQEHESAEGLFTGLVKRYALEQSTTEKPSVNLLGFTSLGFHLRSDLISLRRILKTLGVEVNVVAPWGAGIEDLRNLPAGWVNVVPYHEMGPGAAHHLREKFGMPSLQGIPMGVNPTLDWIRDLLELLNVIAAEKGLPSIEMPPLTDFSLDGLSAPSGVPWFARTADMESFSGKRAFVFGDATHTVGMVKFLKDELGMQIIGAGTYLEQHADWIRDQLEGYLPVPLMVTDKFQEVAKKIEDEMPELVCGTQMERHSCRKLDVPCMVISTPTHIENHLIGYYPILGFDGADILADRVYTSCKLGLEKHLIDFFGDAGLEYEEEEPESISNGHAAAAGSEGGVPDSGEAGDAGDTDGMPWSPDAEKMLRKVPFFVRKKVRKNTENFARENGEATITAEVFKRAKEALGG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: RSMG_BACAH
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFEIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVREAYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGDLKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_ACISJ
Sequence: MNTIHVDVVSAEESIFSGEARFVALPGEAGELGIYPRHTPLITRIKPGSVRIELPDGNEEFVFVAGGILEVQPDCVTVLSDTAIRGRDLDDQKAQEAKAAAEEALKNAKSEIDLARAQSELAVMAAQIAALRKFRQKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RCN1_HUMAN
Sequence: MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL
What is the function of this protein?
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
What are the official names of this protein?
Reticulocalbin-1.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: DER_NATTJ
Sequence: MSVKATVALVGRPNVGKSALFNRIVGQRISIVDDTPGVTRDRIDGKGEWSGHSFNLIDTGGIFDEEDDILKQVVIQAEVAIDEADVIVFVTDGRDGITPADEEVAATLRKTKKPVLVAVNKSEGNYDQYAMEFYQLGFEQVISISALHGTNTGQLLDEIVELLPEQEYEELNYHEDDIMLSVIGRPNVGKSSLINKILNKERLIVSNMPGTTRDAIDTVIEREDQKYVFIDTAGLRKKSKIDERLEKYSVIRSIKGMERSNIALLLIDVTKGILEQDKKIAGLAEEKGKGLIILLNKWDAIEKDGKAGDKYYETVRLELPSVNYAPIMFLSAQTGKNVEKIFPVIDKVSKEHSKRITTADVNRVIEDAVNYTPPPSKKGKRLKIYYATQVRTRPPTFVLFVNNPELMKNSYKRYLQNQLRRAFGFEGTPIRILERVKQRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CHLB_GLOC7
Sequence: MKLAYWMYAGPAHIGTLRIASSFKNVHAIMHAPLGDDYFNVMRSMLERERDFTPVTASVVDRNVLARGSQEKVVDNIVRKDQEETPDLIVLTPTCTSSILQEDLQNFVDRAQMDAKGDVMLADVNHYRVNELQAADRTLQQIVQYYLEKGRKKGELPTGKTEKPSVNIIGMTTLGFHNQHDCTELKRLMADLGIEVNEVIPEGASVQNLKNLPRAWFNLVPYREVGLMAARYLEQEFSMPYVDITPMGVVETARCIRKMGQLLNQQGANVDYEEFINQQTLYVSQAAWFSRSIDCQNLTGKKAVVFGDNTHAAAMTRILAREMGIHVVLAGTYCKYDADWFKEQVREYCDEILISEDHGEIADAIARIEPSAIFGTQMERHVGKRLDIPCGVIAAPIHIQNFPIGYKPFLGYEGTNQIADLVYNSFTLGMEDHLLEIFGGHDTKEVITKSVSADSDLNWNKEAQTELNKVPGFVRGKVKRNTEKFARERGFSEITLEVMYAAKEAVGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: NTR1_RAT
Sequence: MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
What is the function of this protein?
G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:23051748, PubMed:24453215, PubMed:26205105).  Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system.  Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis (By similarity).
What are the official names of this protein?
Neurotensin receptor type 1, NT-R-1, NTR1, High-affinity levocabastine-insensitive neurotensin receptor, NTRH.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft. Note=Palmitoylation is required for localization at CAV1-enriched membrane rafts.
Protein: CUTI1_HYPJQ
Sequence: MRSLAILTTLLAGHAFAYPKPAPQSVNRRDWPSINEFLSELAKVMPIGDTITAACDLISDGEDAAASLFGISETENDPCGDVTVLFARGTCDPGNVGVLVGPWFFDSLQTALGSRTLGVKGVPYPASVQDFLSGSVQNGINMANQIKSVLQSCPNTKLVLGGYSQGSMVVHNAASNLDAATMSKISAVVLFGDPYYGKPVANFDAAKTLVVCHDGDNICQGGDIILLPHLTYAEDADTAAAFVVPLVS
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).
What are the official names of this protein?
Cutinase.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRBB2_RAT
Sequence: MASDHQTQAGKPQPLNPKIIIFEQENFQGHSHELSGPCPNLKETGMEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIVDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDNSDFGAPHPQVQSVRRIRDMQWHQRGAFHPSS
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin B2, Beta-B2 crystallin, Beta-crystallin Bp.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: DSRB_ECOLU
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: BDBC_CHLTR
Sequence: MIKHLRSYCLYLAWLFSCIGTLMSVYYSYILNVEPCLLCYYQRICLFPLVVILGIAAYREDISIKIYTLPLALVGFGIAIYQVCLQEIPGMTLDICGKVSCSTKLFLLGFITMPMASAAAFCAIACLLVLATKSK
What is the function of this protein?
Required for disulfide bond formation in some proteins.
What are the official names of this protein?
Probable disulfide formation protein, Disulfide oxidoreductase, Thiol-disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. BdbC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_SALPC
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMDDVAPQEKVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMGTPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: APT_STRCL
Sequence: MTGGAQELLLSRIRDVPDYPQPGVVFKDITPLLADPEAFSVLTEALAEVCVRHGATKVVGLEARGFILGAPVAVRAGLGFIPIRKAGKLPGATLSQAYALEYGTAEIEVHAEDLTPDDRVMVIDDVLATGGTAAAAMELIRRGGADVAGLAVLMELGFLGGRARLEPTLAALEALLAL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_RHIL3
Sequence: MARVKRGVTSHAKHKKVLKAAKGFYGRRKNTIRTAKAAVDRSKQYAYRDRKVNKRNFRALWIQRINAAVREFGLTYGRFIDGLNKAGIEVDRKVLSDMAIHEPEAFGALVSAAKKALEYLKEAGTANEFEGAVK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SSRP_STAAW
Sequence: MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIIKLGDQTREIGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NEUV_TAKRU
Sequence: MPQCALLLSLLGLLALSSACYIQNCPRGGKRALPETGIRQCMSCGPRDRGRCFGPNICCGEALGCLMGSPETARCAGENYLLTPCQAGGRPCGSEGGRCAVSGLCCNSESCAVDSDCLGETESLEPGDSSADSSPTELLLRLLHMSSRGQSEY
What is the function of this protein?
Vasotocin is probably an antidiuretic hormone.
What are the official names of this protein?
Vasotocin-neurophysin VT 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAP26_HUMAN
Sequence: MAPVRRSAKWRPGGIEARGEGVSTVGYRNKNVRQKTWRPNHPQAFVGSVREGQGFAFRRKLKIQQSYKKLLRKEKKAQTSLESQFTDRYPDNLKHLYLAEEERHRKQARKVDHPLSEQVHQPLLEEQCSIDEPLFEDQCSFDQPQPEEQCIKTVNSFTIPKKNKKKTSNQKAQEEYEQIQAKRAAKKQEFERRKQEREEAQRQYKKKKMEVFKILNKKTKKGQPNLNVQMEYLLQKIQEKC
What is the function of this protein?
Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC).  Enhances homeobox protein Nkx-2. 1-activated SFTPB and SFTPC promoter activities.
What are the official names of this protein?
Thyroid transcription factor 1-associated protein 26, TTF-1-associated protein 26, Coiled-coil domain-containing protein 59, TTF-1-associated protein BR2.
What is the protein family that this protein belongs to?
Belongs to the TAP26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURE_PORGI
Sequence: MKLEQYLSELRPIAVIGNIEQEVSDIASDSRKATDGALFVAVRGTLTDGHRYIPQAYTQGCRAFVVEDLPDEKPEGCCFVQVSDTAEALASLASAYYGHPSRHLTLVGVTGTNGKTTVATLLYRLFRKMGYKAGLVSTVCNYVDDRSEPTTHTTPDPLALNALFRRMADAGCEYAFMEVSSHAAAQKRIGALDFDGGIFTNLTRDHLDYHGSVPEYLRAKKSFFDGLGAQAFALVNADDKNGLVMVQNTRARVCTYALKSMANYRAKIVERHIDGMDMYMDDREVFVRLVGDFNAYNLLCVYGASCELGQDREEVLRILSELTSVDGRFQTFTSKDGYVAIVDYAHTPDALINVLDTIRPLAKSHKVITVVGAGGNRDKGKRPIMAKEAARRSERLILTSDNPRDEEPQEIIQEMAIGLSTEDRKKTLLITDRAEAIRTACMLAEKGDFVLIAGKGHETYQEIRGVKHHFDDREVVCDAMSKDRIVQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_CLOBH
Sequence: MKITKNILKAEFIKRPNRFQAYVKINEKIEMVHVPNTGRCKEILIPGSMVILREENNENRKTRYDLIAGYKGDMLINIDSQIPNKVVHEALMNLKIDILKEYTNIKREKTFGKSRFDFKLEKENGEIYYLEVKGVTLENDGLTMFPDAPTERGTKHILELIDVKNKGMGAGVLFLIQLNGVKKFTPHHKMDKNFGEALRLAKEKGVDILAYDCLVEESSISLNNPISIEI
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: SYD_THEKO
Sequence: MYRTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDPELFKLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDTRLDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMKYFEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDSEMAFIEDEEEVMSFLERLVAHAINYVREHNAKELDILNFELEEPKLPFPRVSYDKALEILGDLGKEIPWGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPEICRAFDLEYRGVEISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGLGAERLIKQMLDLPNIREVILFPRDRRRLTP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).  Is specific for tRNA(Asp) since it aspartylates tRNA(Asn) 3 orders of magnitude less efficiently than tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA(Asp) ligase, Aspartyl-tRNA synthetase, AspRS, Discriminating aspartyl-tRNA synthetase, D-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_NANEQ
Sequence: MNRIISINGPLVIAKGKFSIFEVVRVGEEKLIGEVIGIENDKAYIQVYEDTNGLKVGEPVFNTGKPLTIELGPGLLANIFDGLGRPLKDIYEKTQSIYIPKGIDLPTLDRKKVWEFIPKKKKGDTIKGGDIIGTVNENGFEHRIIVPPNVEGKIEEIYEGNFTIEETIAIVNGKPIKLYHEWPIRKPRPYKEKLDYNYPFITGTRVLDIMFPIAKGGSAAVPGPFGSGKTVLNQQIAKWADSDIVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGATIGEYFRDQGYSVVVNADSTSRWAEALREISSRLGEIPSEEGYPAYLLRKLAEFYERSGRVRTLNDLEGSLTIIGAVSPPGGDFSEPVTQNTLRLVGALWALDSKLAYKRHYPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGPDALSDNEKIYLHMGRIIREGFLQQDAFDENDSYSPLEKTIELMRIIHKYYVTVKQLLGKIPLEEIEQKGIHEKIIKLRYKSLKEFREEIKAIEQEILSLLNSQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: DNAI7_MOUSE
Sequence: MAPKSKKAPSKKKMTKAERLRLMQEEEERRLKEEEEARLKFEKEEQERLEIQRIEREKWNLLEKKDLERRSQELEELALLEGCFPEAEKQKREIRALAQWKHYTECDGSPDPWVAQEMNTFISLWEEEKNQAFEQVMEKSKLVLSLIEKVKLILLETPTYELDHRTVLQHQGSILRLQELLSLKINVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSNVALRLLHTRYDHITPLFPIAVTEQNQNPVGAEQVNVEESTEKAMTEEKLFTEEKAANEDEQPKAEQERELNLVQEENKYEAIENTVLQRTSDSEGEDSQTTQLELEMKLLSEAVLAAQLCLVENVVELPEASQAYKVDLCHFSTLGGVYHLDVLELPPQCKPVKGWVLVEILQEGLQRFIYPPDTTEEPDPDVTFPPIEVTLEIHKSVIFFERPRVVRWDNEGKFWRSDGISSVYYNREDRLLTFSMDTLGPVTLIQDAHVNMPYQSWEMSPCGMNKVLLIVKTVFMELQIYIKENLCMLASVKLRGKGLEFHLKGKWMAPIPFILALKEAGLNIFPAVYSHFYVVINNKVPQVELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVIRVREQLSEETEHHTWSLLMFSGDRAQMLKMQEENDKFSEALREGTEFHSTLYHMMKDFASPVAMERVRHSNCQFIDSVCYMLLSIRVLSYS
What is the function of this protein?
Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180).  May also act as a cell cycle regulator (PubMed:17974961).
What are the official names of this protein?
Dynein axonemal intermediate chain 7, Cancer susceptibility candidate gene 1 protein homolog, Protein CASC1, Cilia and flagella associated protein 94, Lung adenoma susceptibility protein 1.
What is the protein family that this protein belongs to?
Belongs to the DNAI7 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm. Note=Colocalizes with microtubules in interphase.
Protein: RECF_CLOB8
Sequence: MYVKNINLLNYRNYKKLSVELTENVNVFVGDNAQGKTNILESVYYCAFAKSHRTSKDKELINWENSTAYISLLIGKNRLDKKIDINILRDGKKAIKVNNIKVNKIGELFGIFNVVMFSPEDLKVIKEAPSLRRRLLDMELSQVNPNYYFNLVQYNKVLGERNILLKSRSFSEDILDVYDIQLSKYADYIISKRLEYINKINFYGDIIHREITSGKEEINFKYNCTVNLENGKFKDNYLKKLKDNIQKDREKGLTSVGPHRDDFSVFINNIDTKIFGSQGQQRTSILTMKFASLKIIREITGEYPVLLLDDVLSELDLNRKKYILRSIKDIQTIITCAGIEDLNDYLDDKVKIFNVSNGQILNQGRNI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_STRCO
Sequence: MARVSGVDIPREKRVEIALTYVFGIGRTLSQQTLAATGVDPNTRVRDLSEEQLVAIREYVDNNIKTEGDLRREVQADIRRKVEIGTYQGLRHRRGLPVRGQRTSTNARTRKGPRRAIAGKKKPGKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CJA_CONDI
Sequence: MSTLGILLPIALLLPLANPAENGDGQAMPRTRNLRSLSFGRTLRRLEKRGCDPTDGCQTTVCETDTGPCCCKPNFTCQISNSGTKSCSCSGQPSDCPV
What is the function of this protein?
Injection of the synthetic peptide causes a hyperexcitable phenotype in mice greater than three weeks of age at lower doses, and lethargy at higher doses.
What are the official names of this protein?
Conotoxin Di19A, Conotoxin di16a.
What are the subcellular locations of this protein?
Secreted.
Protein: SYM_CALMQ
Sequence: MLDRRIFSDPNGNEVRWVVGSAWPYIYAVPHLGNLIGSLLSADVFTRYLKLKGYDVVFVTGSDEHGTPIEVEAIKLGIEPRQLTDRMHEIIVKLLKLWGIEPDNYTRTESEVHKWYVRDAFTKIYNNGYIFTKDDELPYCPRDKIFLPDRFVIGTCPYCGYPYARGDQCENCGRLLEPRMLINPKCAICGSTPEWRLTRHWYLDLRRLEDRIRSYIEGNSALPDNAKQMSLGILKEGLRPRAITRDNKWGIPAPFPGAEGKTIYVWFEAVLGYVSATIEYFRRLGREDDWRRFWFNKGTRVVFFIGKDNIPFHTIIFPALLMATGEDYVMPWTTSSTEYLIFEGKKFSKSQRVGIWADEAIALLPADYWRFYLIYNRPEQRDSNFTWDSFLDVVNSIMNDTVGNFIHRVLTLAKRRWGTVPGDVKMIEQDQEIYGKVLEILNTVEEDYERIMLKDAVSQSIEIARIGNKYLNERQPWRLSEVEFNSAIYMLMSIVKTLSITLAPVIPFSINELWRMMGYSNGLRWGDARKPIEQGLRLSEPKPLFRKISKEELNVMLKKLDEIRDIKDKGKYPWEQAYLPNP
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMCB_ECOLI
Sequence: MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWLPNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSMIMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANTFVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMVASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIAGGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLILKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFRKRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLDTLFNQLTAEHKH
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific cryptic EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 1CPX_DIRIM
Sequence: MTKGILLGDKFPDFRAETNEGFIPSFYDWIGKDSWAILFSHPRDFTPVCTTELARLVQLAPEFKKRNVKLIGLSCDSAESHRKWVDDIMAVCKMKCNDGDTCCSGNKLPFPIIADENRFLATELGMMDPDERDENGNALTARCVFIIGPEKTLKLSILYPATTGRNFDEILRVVDSLQLTAVKLVATPVDWKGGDDCVVLPTIDDTEAKKLFGEKINTIELPSGKHYLRMVAHPK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
1-Cys peroxiredoxin, 1-CysPxn, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.