PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_DICTD
Sequence: MKEEVLGLPIDKIEKKIKEYDFSPRISNIGYVKHVGDGVAEVSLLNSAFIGEMVVFESGIQGMVLSLKEDSVGVILFGKDEYVKEGDVVYSTSKILQVPTGNGFLGRVIDPLGNPIDGGGLIFPEAYVPIDNEAPSIFDREPVKEPLYTGIRTIDALIPIGHGQRELILGDRQTGKTTIALDTIISQKNYGTICIYVAIAQKRTNIARIVQTLREYGALSNTIVIATFPDEPPALRYIAPMAGCAMGEYFMRQGERVLIVYDDLTKHANTYREVALLLRRVPGREAYPGDIFYLHAHLLERAAKLNKRLGGGALTALPIAETLSGEISTYIPTNLISITDGQIYLDTNLFNAGIRPAINVGLSVSRVGGSAQPKGMRQVAGRLRLDLAQYREYAMFLEFGTELDMATKKKIERGRRVEELLKQGAHEVQPIEEQIISFYLANGGFLDNYPVEKVKDVVIKYIAYLKLKYSSVLTFLREELQLSDQIIYQLHNIFQEFEKEVYANSTGS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: APOC2_THEGE
Sequence: MGTRFLLALCLVLLVLGFEVQGAQLPQQDEQPSPALLSQVRESLSSYWESAKAAAQKLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE
What is the function of this protein?
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma.  Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.  Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase.
What are the official names of this protein?
Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KPTA_BURL3
Sequence: MNTKKNELPAPDATRISRTLSYLLRHAPQTIGLQLDPEGWADIDELIAGIARQGLHLDRATLETVCATNDKQRFALSDDGRRIRAVQGHSTPVVQRRYPAAQPPERLYHGTATRFLDSIRAQGLKPGARHHVHLSPDIRTALAVGTRYGVPVILEVDAQRMHRQGHTFFVAENGVWLTDTVPAEFLKEMDQPAR
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: BIOB_CITFR
Sequence: MAHSS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: S39A1_HUMAN
Sequence: MGPWGEPELLVWRPEAVASEPPVPVGLEVKLGALVLLLVLTLLCSLVPICVLRRPGANHEGSASRQKALSLVSCFAGGVFLATCLLDLLPDYLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALHSVFEGLAVGLQRDRARAMELCLALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSCMTPLGIGLGAALAESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSEQRILKVILLLAGFALLTGLLFIQI
What is the function of this protein?
Transporter for the divalent cation Zn(2+).  Mediates the influx of Zn(2+) into cells from extracellular space (PubMed:11301334, PubMed:12888280, PubMed:16844077).  Functions as the major importer of zinc from circulating blood plasma into prostate cells (PubMed:12888280).
What are the official names of this protein?
Zinc transporter ZIP1, Solute carrier family 39 member 1, Zinc-iron-regulated transporter-like, Zrt- and Irt-like protein 1, ZIP-1, hZIP1.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.
Protein: TRM5_MACMU
Sequence: MVLWILWRPFGFSRRLLKLERHSITESKSLIPLAWTSLTQTLSESPGIFLLGQRKRFSTMPEIETHERDSELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSRLMRSLRRAALQRPGIKRVIEDPEDKESRLILLDPYKIFTHDSFEKAELSVLEQLNVSPQISKYNLELTYENFKSEEILRAVLPEGQDVTSGFSRVGHIAHLNLRDHQLPFKQLIGQVMIDKNPGITSAVNKINNIDNMYRNFHMEVLSGEQNMMTKVRENKYTYEFDFSKVYWNPRLSTEHSRITELLKAGDVLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLHNCKLNKVDQKVKIFNLDGKDFLQGPVKEELIQLLSLSKERKPSVHIVMNLPAKAIEFLSAFKWLLDGQPCSNEFLPIVHCYSFSKDANPAKDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPAAVLYKNQTKNPENHEDPPLKRQRTAEAFSDEKTQIASNT
What is the function of this protein?
Involved in mitochondrial tRNA methylation (By similarity).  Specifically methylates the N1 position of guanosine-37 in various tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: KPSM1_ECOLX
Sequence: MARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLLILLGILGYVMHRTMPDISFPVFLLNGLIPFFIFSSISKRSIGAIEANQGLFNYRPVKPIDTIIARALLETLIYVAVYILLMLIVWMTGEYFEITNFLQLVLTWSLLIILSCGVGLIFMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVMPGYISEGVSLNYLAMFTLVTLFIGLALYRTREEAMLTS
What is the function of this protein?
KpsM and KpsT constitute a system for the transport of polysialic acid across the cytoplasmic membrane.
What are the official names of this protein?
Polysialic acid transport protein KpsM.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI_AGRVS
Sequence: MHAIVEQLKSTVAATAATDIRGAFASDPKRFERFSSRFDDLLMDYSKCAVNDEIMALLETLCTQAGVAEKREAMFNGEAINFTEGRAVLHTALRNRANTPVVVDGKNVMPDVNAVLHAMSAFAEGLRQGTITGSTGLQITDVVNIGIGGSDLGPAMATLALAPFHDGPRLHFVSNVDGAHIADTLKLLEPETTLFIVASKTFTTIETMTNAATARAFIASALGEDAVGDHFAAVSTALEKVAAFGIGSDRVFGFWDWVGGRYSIWSAIGLPLMIAVGADNFVEFLAGAHAMDMHFRTAPFRENLPMLLGAIGYHHRNVLDYPTRAILPYDQRLSRFPAYLQQLDMESNGKGVTIDGSPVKGNSGPVVWGEPGTNGQHAFYQLIHQGTSVIPAEFMIAAKGFEPELRHQHDLLIANCLAQSAALMKGRTLDEAKGQLLKSGMDQAKADHIAPHRVFTGNRPSITFVYEQLTPFALGRLIALYEHRVFVEGVLFGINSFDQWGVELGKELATGLLPVVQGKAGTDGQDASTAGLVAALSDLGR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMAND_PECPW
Sequence: MLPTIITDIECLVTRPDRHNLVTVVVHTNKGVTGYGCATFQQRPLAVKAMVDEYLKPLLVGRDANHIEDLWHMMMVNAYWRNGPVINNAVAGVDMALWDIKGKLADMPLYHLFGGKSRDAIAAYSHAASDTLDGLYQEVERLYAQGYRHIRCQLGFYGGNPDALHSTRQPTEGAYYDQDQYMANTLAMFRALREKYGDRFHILHDVHERLFPNQAVQFAKAVETYRPYFIEDILPPAQNEWLAQIRSQSAVPLATGELFNNPAEWQNLVINRQVDFIRCHVSQIGGITPALKLGVFCQNFGVRLAWHCPPDMTPIGAAVNIHLNIHLHNAAIQEFVAYPENTRKVFPQAVEPENGYLYPIERPGIGVGIDLDAARQFPVVYRPHEWTQSRLPDGTIHTP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member Pecwa_4254.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: SYQ_BUCAT
Sequence: MDTKKEIKNNNFICQIINKDLNENKNLSFYTRFPPEPNGYLHIGHAKSICLNFELASLYKGRCNLRFDDTNPLKENIKYIKSIKHDINWLGYKWHGNVRYASEYFLKLYQYAQELIKKGLAYVDHLTKEQIREYRGTLNTPGKNSPYRNRTIQENIELFEKMKKGDFSEGEACLRAKINMSSSSIIMRDPVLYRIIFIKHHQTQNKWCIYPMYDFAHCLSDSIEGITHSLCTLEFQDNKFLYNWILKNTSVKHYPKQYEFSRLNLEFSILSKRKIKILIDKNIIEGWDDPRIPTLSALRRKGYTPSSIKNFCQKIGVTKQNNLIEFSMLEHCIRKELNQTAIRTMAILDPIKIFLYNLDSNYKEEFIVPNHPNNPEMGTHKIIFTNTIYIDRSDFKEKYDKKYKRLKLGEKIRLRYSYIIHAEKIEKDEYGNISNIICYCDLNTLGRKPKDNKNPAVIHWISEKNTLSAEFKLYDQLFNIKNPEQQENFLLYINSKSLIKKFGFIEKKIGEEIQKKISNNNIEIFFQFERIGYFCIDFIDSKKNQLVFNRTVGLRDTWDSKKIKTKNITNN
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTR3_YEAST
Sequence: MNMGGSSSTAAKKATCKISMLWNWYTIDTCFIARSWRNDTKGKFAGSCIGCFALVVVAQWLTRFSRQFDVELLKRQKIKHLASYSPEEYVVKCGEEDAKSDIEELQGFYNEPSWKTTLISLQKSFIYSFYVWGPRRLNEPEDDLLKKVLSCCTLITPVDLYPTFLDHMIRVTIFVLQWGLSYIIMLLFMYYNGYIIISCLIGAIVGRFIFCYEPLGSLGANGSAQGTVSYDKESDDRKCCL
What is the function of this protein?
Required for high affinity copper (probably reduced Cu I) transport into the cell.
What are the official names of this protein?
Copper transport protein CTR3, Copper transporter 3.
What is the protein family that this protein belongs to?
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: ACPS_NOCSJ
Sequence: MIVGVGIDVVDVARFGVSLSRTPGLTDRLFTPEEAERPLASLAARFAAKEALAKALGAPEGMHWHDAEIRSEESGRPVFEIRGSVLRRANDLGVGSVHVSLSHDAGIASAVVVLES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_LACDB
Sequence: MSQAIIAAKAKFVEEFAEELKSAKSIVVINYLGLTVDQVTAFRAELRESNAKMKVVKNTYLRRAAAQAGLDDLAPVFVGPSAVIYTDDEDNVTAPARIAADYAKKFDVVEIKGGALEGQVATKEQVEELAAIPGREGLLSMLLSVLQAPVRNFAYVVKAVAESKEESAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MNME_SALPK
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPRYADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPGVRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDANDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVRNKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNNLKQSMGFETNMEGGFLARRRHLQALAEAANHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_DRIWI
Sequence: METATLVAISISGSLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RECR_MYCTU
Sequence: MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPSDIDRLTGVLAKVRDGVRFCAVCGNVSDNERCRICSDIRRDASVVCIVEEPKDIQAVERTREFRGRYHVLGGALDPLSGIGPDQLRIRELLSRIGERVDDVDVTEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRVLA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RS19_STAA3
Sequence: MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DPO4_SHEB5
Sequence: MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSSDRRGVISTCSYEARKFGVRSAMATAYAFKLCPDLILVPGRMQVYKDVSLQIREIFSRYTQLVEPLSLDEAYLDVSECQQYKGSATLIAQAIRRDILAETGLTASAGIAPVKFLAKVASDLNKPNGQYVITPETLPEFVKTLSLRKIPGVGKVTAEKLSSLGLNTCGDVQAYSKPELLARFGKFGGVLIERSQGIDERGISADRERKSVGVETTLAKDIYSLEQCQQVMPGLIQELALRLSRSAKERKIHKQVVKLKFNDFKQTTIEHRSDEVSIVMFYDLLAQAMARQEGRGIRLLGISVGLADSILAVSEIPNAQTQLDLAL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCDX_ECO81
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTKSMIATIASGNVHIISHPGNPRYPIDFKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: RIMM_SYNJA
Sequence: MVASRDTAWLLVGQVVAAHGLRGWLRVKCWSDFPERLTEPGPRWLQRDSDPEPLLHPLIEGQFFPAKGLYLVRLEGIPDRTAAEAWVGAKVLVPASQRLPLEPEEYHYSDLIGLAVYHQGRLLGHVSAIWAAGQDVLEIATPDKRQVLIPFVKALVPVVDLEKGELQVQPPPGLVESFLGQDRARN
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_SYNP6
Sequence: MEAALLLAKLPEAYQIFDPLVDVLPVIPVFFLLLAFVWQAAVGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HSL1_YEAST
Sequence: MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS
What are the official names of this protein?
Probable serine/threonine-protein kinase HSL1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
What are the subcellular locations of this protein?
Bud neck.
Protein: CD3G_SHEEP
Sequence: VKVDDNQEDGSVILICVTDEKKITWLKDMKEISSGDTNKLTWDLGSSTKDPRGIYECKGSSNESKSLQIYYRMCQNCIELNLATVAGFIFTEIVSIFLLAVGVYFIAGQEGVRQSRASDKQTLLNNDQLYQPLKEREDDQYSHLRKK
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.  In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface.  Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
What are the official names of this protein?
T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LPXK_RICCN
Sequence: MIKLLYPEFWQKRNIIAYLLLPISVIYKFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKSRNVSFVIVTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLLNELKPDIIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPNILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFFATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNATLVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKKA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: HSLV_BURM1
Sequence: MEQFHGTTIVSVRRGDKVALGGDGQVTLGNIVMKGGARKVRRIYNNQVLVGFAGGTADAFSLLDRFEAKLEKHQGNLTRAAVELAKDWRTDRMLRRLEAMLITADANTTLVITGNGDVLDPEGGICAIGSGGAYAQAAARALAENTELSPREIVEKSLEIAGDMCIYTNHNRVIETIE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK_CHLTR
Sequence: MLRQETAPLVCKFGGTSVGTAQSIRRVCEIIQEERPSFVVVSAVAGVTDWLEEFCRLPKGKRAALTEKIRERHESIAKELGIEVSLAIFWEILEHFEDVEELFSEDQARILAIGEDLSSTLICSYCCTYVLPLKRLEARQVILTDSQFLRAVPDLALMQTAWGELALQEDTIYLMQGFLGATSSGKTTVLGRGGSDFSASLIGELCKARELRIYTDVCGVHTADPKILKDTQLIDSLTFEEMQELASSGAKVLHQDMLKPCVRAKVPIFVTSTFNVTKEGTWICASLNESTEGPVIKALSLKSNQALWFVEYNSPLVRLEDVLGCVRSLGFVPGVVMAQSLGVYFTIDWEEYPQTITKALEAFGTVSCEGPLSLVALVGAKLASWSMSRVFEALHRTPVLCWSQTDTVINLIINKDFGVAVTELLHDCLFK
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: CXA1_MOUSE
Sequence: MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDSQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
What is the function of this protein?
Connexin 43 is possibly the ATP-induced pore of mouse macrophages.
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and proper localization at ICD is dependent on TMEM65.
Protein: DAPA_ALIFM
Sequence: MFSGSIVALVTPLDTDGEVDYNSLKSLVDYHIKAGTNGIVAVGTTGESATLSVEEHVKLVMKTLEFADGRIPVIAGTGANATHEAVTFSKLFHDSGVAGCLSVTPYYNKPTQEGLFQHYKAISEATDIPQILYNVPGRTAVDLLPETVARLAELDNIVALKDATGDLERVAITRELCGENFIQLSGDDATALDFVKLGGHGVISVTSNIAAKDMATMFALAAQGKFEEAEIINQRLMPLHNDLFVEANPIPVKWAAHRLGMITHSDIRLPLTELSLSAQPTVEQALKSAGLLK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.