PharMolix/UniProtQA huggingface dataset:
Protein: VPS10_EMENI
Sequence: MIPRWIQLVGCLLLALMLPPSAAKKDKPGISFHKLHEKPYSMFYFEKSDTVLLNLEDGEVLRSFDAGENWEVIEDNGMKHGVTSIHQHPFDEDKAYALGDDGKHWITTDKAKTWKSFKVPDQAYFKSPQTGPLTFHGRDSSKVIFETRPCPSCAPRSYYTTDDFDTIEVLTESAVGCYWAVGNPQFAAGPNMPKGMEERTVCVVPGLKASSRFAFRLVYSDDYFRSQGIETKLQDGRPVSGVTSIAQVKSFIVAAVESQGTTERALYVTTDIEKWHRAEFGDHRLEQDAYTVLESSDYSLQVDVLTNPFSGMGVLFTSNSDGTYFTRNIEHTNRGPRGYVDFEKLAAIQGIVLVNTVRNPDDVEAGASKEVVSQISFDDGRTFQPLKSTDGQRIHLHSVNSDTNLGRVFSSPAPGLVMGVGNTGDYLGKRSDGHLYVSDDAGLTWRLALKGPHKYEFGDQGAVLVAISEAPKVKKIEYSLDHGKEWKSVDLPHEVDGETSTLTTTPDSTSLKFILLGHSKGEPSVYAIDFEDLHERKCEDEDFDNHWPARLDEHGEPDCLMGQKQFFRRRKANADCFVAEAFNSSMSKFEPCKCTVEDFECQSTRTEDGKDCVPPKSFTPPDGDCINPDDTTMIPSGWRLIPGDVCVRDDGVNLDKDVEIPCKDVNNRPKSKEITSTMKMFSSGLSAYRYLERQVSNLGEDETVLMLSRNQELFVSHDHGQTWQQELKGASIMKIVPHPYNSDTAYILTDSEEVFYTINRGATFGSFRAKTLPDYENGPILRFHPLKRDWLLWVGTECDSGSCHSNAYFSDDRGDSWKTILRHAKKCEFEYKENRPDSLYLVFCEQYENEDDKKRLQLMSTTDERFSDWETVEENLVEYATRAEYIILASHTDKDNALKARVSVDGTTFADLKFPPNVVPAQNLYTLVDASEHAIFLNGTTYVLSLDAVNQNDWGYVDFERMQALEGVIIANIVSNVDELSDGAPKRLRTMITHNDGGEWTLLAPPTKDANGKKFPCSVVEGKGTEDCALHLHGYTERADPRDTFSSGSAIGLMMGLGNVGDRLTSKDEADTFLTMDGGITWKSVKKGRYMWEYGDSGSVIVIVSEQKSTKVLHYSTDEGATWQDYYFSDEEIEVIDISTVPSDTSKKFILWGKKSDELVTVNVDFSGLYDRDCEFDDKGGDVSDDYQLWTPKHPFQEENSDYECDYNYERQNDGTCKLVPGLKPHDPVGYCKAHPDAIEYFEPTGYRRIPQTTCQGGYNLDHQTAKPCPGKQQEYDKKHGISGIGLFFAIVAPIAVAGAVGYYIYTKWDGKFGQIRLGETSTGTQGILSRDSLLVTVPIAIIAGIVAVAKALPLLVTSLWRSASGYMRVGNRSYPRPYASRASFAARRGDYSSVVEDEDELLGVVDFDGDEEEDS
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: VMP1_BOVIN
Sequence: MAENGQNCDQRRVAMNKEQYNGNFTDPSSVNEKKRRDREERQNIVLWRQPLITLQYFSLETLVILKEWTSKLWHRQSIVVSFLLLLAVLTATYYVEGAHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAETAQDFASRAKLAVQNLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKLFVIVAFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHRSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSYAKRIQQRLDPKEKTK
What is the function of this protein?
Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes.  Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine.  Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly.  Regulates ATP2A2 activity to control ER-isolation membrane contacts for autophagosome formation.  In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required.  Modulates ER contacts with lipid droplets, mitochondria and endosomes.  Plays an essential role in formation of cell junctions (By similarity).  Upon stress such as bacterial and viral infection, promotes formation of cytoplasmic vacuoles followed by cell death.  Involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis (By similarity).
What are the official names of this protein?
Vacuole membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the VMP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KUP_VIBC3
Sequence: MKPAKQTTASLAFLAMGIVYGDIGTSPLYAFKEVFFSHHPLAINPDNVLGILSLVFWAFVLIVSIKYLLLVTRADQNGEGGILTLSAIAQQNAPKPWRRIAMLLGILATGFFFGEAVITPAMSVLSAVEGIAVAQPDLAPYVLPIAMMIIVALFAVQAMGTERIGRFFAPVMLLWFLVLALLGAHAIWHAPQVLRALNPAYAVHFVLLHGQHTLFILGLVVLSVTGVEALYADMGHFGIKPIRIAWFALVMPSLLLNYFGQGAYLLTLSAPTGSTFFSLAPKAWLWPLILLATFATVIASQAVISGIFSLARQAINYGYLPPMKIAHTSEHSQGQIYVPAANMLLFVAVIFVMLRFRSSANLAAAYGIAVTAIMMISSLLLVLVARYQWQWRWPRVVTIGIAFIGMDTLLLASTSTKLMEGGWLPLLLGCVVFIVMYIWQQQRQRLLEIAGNELSVSAMIQSLEEESFQRAAGTAVYLSRSLNHVPRSLLHNIKYNKTLHERNVLMTFQYEAVPRVHPCRRAEIEQVSASFWQVVIHIGYQEEPDMAQVMHCCGLKGLYLHPNETLFLLSSERLKVQKLGMWHDLKVWFFIQMSKHALRTSERLNIPPDRLIEMGVYREM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CXG3_HUMAN
Sequence: MCGRFLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRRHKKATDSLPVVETKEQFQEAVPGRSLAQEKQRPVGPRDA
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction gamma-3 protein, Connexin-30.2, Cx30.2, Connexin-31.3, Cx31.3, Gap junction epsilon-1 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: NDHJ_DRANE
Sequence: MQGTLSVWLAKRGLIHRSLGFDYQGIETLQIKPEDWHAIAVILYVYGYNYLRLQCAYDVAPGGLLASVYHLTRIEYGVNQAEEVCIKVFTQRSNPRIPSVFWVWKSTDFQERESYDMLGITYDSHPRLKRILMPESWMGWPLRKDYIAPNFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RK32_SOLLC
Sequence: MAVPKKRTSTSKKRIRKNIWKRKGYWVALKAFSLAKSLSTGNSKSFFVRQTKINK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFP_PROM0
Sequence: MISSNDFRTGTTIELDGQVWRVVEFLHVKPGKGSAFVRTKLKSVQNGNVVEKTFRAGESVQQAILEKSNLQHTYVESGDYVFMDMTSFEETRLSSEQIGKGAKYLKEGMEVNVIFHNGKVLEVELPISITLKVTETDPGVKGDTASGGTKPAILETGAQVMVPLFISVGEMIRVDTRNDSYLGREN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTP5B_RAT
Sequence: MDSILRLTSILTWLLSGLWHVGLTATNYNCDDPLASFLSPVAYSSSSDITGSTSSAQLNWRMGTGGWSPADSSAHQWLQLDLGNRVEITAVATQGRYGSADWVTSYHLMFSDTGHNWQQYKQENSIWTFAGNLNADSVVHHKLLHSVRARFIRFVPMEWNRNGNIGMRVEVYGCSYKSDVADFDGQSSLLYRFSQKTMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQNGRLVLYLNLDDKKAWLSSITPSAILGSLLDDQHWHSVFLERVGKQVNFTVDRNTQHFWTKGETEVLDIDYELSFGGIPVPSKPGTFVKKNFHGCIENLYYNGVNIIDLAKRRKHQIYSGNVTFSCSEPQIVPITFVNSRSSYLFLPGTPQIDGLSVSFQFRTWNEDGLLLSTELSEGSGTLLLILESGTLRLLIKKVTGHGTESLTGRSLNDGRWHSVSINVRRNRVTLTVDNDAVSLAPETSGLQIYSGNSYYFGGCPDNLTVSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCTQTWTSFYCNCSDTGYTGATCHNSIYEQSCEIYRHRGNKAGFFYVDSDGSGPLGPLQVYCNVTEDKIWMTVQHTITELTQVQGSNSEKPYAMTLNYGGSMEQLEALIDGSEHCEQEVTYRCRRAHLFNTQDEAPFTWWIGRSNERHPYWGGYVPGVQQCGCGLEESCQEIASNTGFLSSKDHLPVTQIIITNSNRTNSEAAWRIGPLRCYGDRHFWNAVSFSTEASYLHFSAFHVEFSADISFFFKTTALSGIFLENLGIKGFLRLEMSSPSEVIFAIDVGNSPIELLVQSPYPLNDNQWHYIQAERNIKETLLQVDNLPKNKREVSDQSNFLLQLSSQLFIGGTSSRQKGFLGCIRSLHLNGQKIDLEERAKITPGVRPGCPGHCSSYGRNCHNGGKCVEKHNGYSCDCTNSPFEGPFCQKEMSALFYSGTSVTYMFQEPYPVAKNTSLSSSAIYKDTAPSKEIVTLSFITAQAPALLLYLKFSPQSFLAILLSRNGSLQIHYQLSKVESHVFTVGSENLANRRVHEVNMNRNGQELSIQVDQQLFSYNFSPEVEFQTVRSLILGKVTETLVLNPEVTQANTLGFVGCLSSVQYNHIAPLKAALRHASIAPVTVQGTLTESSCGSMVESYANGVTTVYSSSDPFGNTDEHEPLTNAIQSDSAFIGGVIAIVTFIAFGVIGIMTHFLYQHKQSHHTNPMKEKEYPENLDSSFRNDIDLQNTVSDCKREYFI
What is the function of this protein?
May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
What are the official names of this protein?
Contactin-associated protein like 5-2, Cell recognition molecule Caspr5-2, Cell recognition molecule Caspr5b, Contactin-associated protein-like 5b.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LIPL_HALH5
Sequence: MSLLLQQHLSQPWRFLDHTSFGPTFQALQSFAYDDTLCTSIGKSQSPPTLRAWVHHNTVVLGIQDSRLPQIKAGIEALKGFQHDVIVRNSGGLAVVLDSGILNLSLVLKEEKGFSIDDGYELMYELICSMFQDHREQIEAREIVGSYCPGSYDLSIDGKKFAGISQRRIRGGVAVQIYLCVSGSGAERAKMIRTFYDKAVAGQPTKFVYPRIKPETMASLSELLGQPHNVSDVLLKALMTLQQHGASLLTESLSADEWLLYEQHFARISERNEKLLAE
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: GLYA_CLOBB
Sequence: MNFEHISREDNEIYALIEKELERQQNGIELIASENVASEAVMEAMGSYLTNKYAEGYPGKRYYGGCYVVDGVEEIARERAKELFGAEHANVQPHSGSQANMAVYFTILEHGDTVLGMDLSHGGHLTHGSPVNFSGKLFNFVSYGVDKDTEEINYDVVRELAIKHKPKLIVAGASAYSRIIDFKKFREICDEIGAYLMVDMAHIAGLVAAELHPSPVPYADFVTSTTHKTLRGPRGGLILCKEKYAKDLDKNIFPGMQGGPLMHIIAAKAVCFKEALDPSFKEYMARVVENCKELGEQLVKRGFKLVSNGTDNHLILVDLNNKDITGKDAEKLLDEVGITLNKNTVPNETRSPFVTSGVRIGTAAITTRGFERRDMEEIADIINETIINRDKDLEQYKQRVEALCEKYPLYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFR2_MOUSE
Sequence: MPRDGTNEQRFLELPSPMSFILNILRNVLEYFGVPVDQDLLICQNKNCGSARSIVRIIGRRLPLKPCRRPHFELIPHVNSTESDDYELRVPSFADVLCVANDEEASCLRFRHSLWQKKEERKIAPFYPSKLTWDPSSPGLRQNKTETDDLPVNEAAIKKIAALEDELTFLRSQIAAIVAMQDLRESRETGFIDLSDEQVPPSSATTGLSVEPDHAPSVVLPPPPPPPPPPQFSLQPPSSLPMQPGSANTHDIDSLATEMERQLSGVKKTDDSHHSKSQRLRDVPNMLDVLKDVNKVRLRPVERSPGGRPVQKRKRRSSEWDPVSLISNALKQKFAFQDDSFDRENSSWECSPFSSPETSRF
What is the function of this protein?
May play a role in mitochondrial aerobic respiration essentially in the testis.  Can also promote mitochondrial fission.
What are the official names of this protein?
Mitochondrial fission regulator 2, DUF729 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the MTFR1 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Associated with membranes.
Protein: FMT_MOUSE
Sequence: MLLPRCCWGRWLMGRRPRCSCQAPAGFDGKDGRGSRVREKPPWRVLFLGTDHFARETLRALHAARDGKEEKLIEKLEVVTVPSLSPKGLPVKQYAIQSQLPVYEWPDVGSGEYDVGVVASFGRLLSEALILKFPYGILNVHPSCLPRWRGPAPIIHTVLHGDTVTGVTIMQIRPKRFDIGPILQQETIPVPPKSTSKELEAVLSKLGANMLISVLKNLPESLNNGRPQPAEGVTYAPKVSAGTSCVKWEEQTSEQVLRLHLAIGDIVPLQTLWMENTVKLLDLVEVNNSILADPKLTGQTVTPGFVVYHRPSQMLLVRCKDGWIGVRSVMLKKTLTATDFYNGYLHAWYQKNSHAHPSQCRFQTLRLPTKMQQKTKLLLCNSALSS
What is the function of this protein?
Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation.
What are the official names of this protein?
Methionyl-tRNA formyltransferase, mitochondrial, MtFMT.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNMG_LACH4
Sequence: MIKTYDSNEYDVIVVGAGHAGCEAALASAHMGQKTLLVTIGLDMVAFMPCNPSVGGPAKGTVVREIDALGGQMGKNIDATYIQMRMLNTGKGPAVRALRAQADKWQYHEHMKDTIENTPNLTLRQAIVDQLVVEDGVCKGVITNTGAKYHAKSVVLTTGTAARGKIIIGELTYSSGPNNTTPSIKLSENLEKLGFKLRRFKTGTPPRVNGNTIDYSKTEEEPGDKTPRHFSYESKDVDYLKNQISCWMTYTNNGTHEIIRENLNRAPMFSGIIKGVGPRYCPSIEDKVVRFADKDRHQIFLEPEGRTTKEVYVGDFSTSMPEEIQLKMVHSVAGLEHAEMMRPGYAIEYDVVEPWQLKHTLETKNIKHLFTAGQMNGTSGYEEAAGQGLIAGINAALSAQDKPGFTLGRNDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLILRHDNADLRLTEYGHELGLISDERYEKFEEKKQAIRDAKERLHEITVHLSDDVQEFLKSIGQEPMKAGVKADVFLRRPNVKIADIERLTGEKIPGDRYVKEQVEIGIKYAGYIKKEETRIARLKRQEAKKIPADIDYEMIEGLATEARQKFEKIRPETLAQAERISGVNPADLAILSVYIQNGRYSKVKKYEAEDLKPSSYFAEKYGLEADAETGASQY
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P3F3B_DANRE
Sequence: MATAASNPYLASSSILSSGSIVHSDSGGGMQQGSAAVTSVSGGYRGDPTVKMVQSDFMQGAMAASNGGHMLSHAHQWVTSLPHAAAAAAAAAVAAAEAGSPWSSSPVGMTGSPQQQDVKNNSGRDDLHSGTALHHRAPHLGPHQTHAGAWGSTTAAHIPSLTGSQQQQQSLIYSQPGGFTVNGMLSPPGSQSLVHPGLVRGDTPELDHSSHHHHHHHQHQHHQQAHHGVNSHDPHSDEDTPTSDDLEHFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQKEKRMTPPGVPQTPEDVYSQVGNGHFLVDYLKDASLTGPSEPGDQRVTTTSSFHQVILAH
What is the function of this protein?
Transcription factor that may play important roles in patterning the embryonic brain.
What are the official names of this protein?
POU domain, class 3, transcription factor 3-B, Brain-specific homeobox/POU domain protein 1.0, Brain-1.0, zfBrn-1.0, POU domain protein 1, ZFPOU1, POU domain protein 23, ZP-23.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_BARHE
Sequence: MSRRHKAEKREINPDPKFGDLVITKFMNAIMFDGKKSVAERIVYGALDVVESKVKSDPVALFHRALENVAPHIEVRSRRVGGATYQVPIDVRPDRRQALAIRWLISAARGRNEATMIDRLSGELMDAANNRGSAVKKREDVHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TRM10_KLULA
Sequence: MSDTSENSNAEIPADTSDVKDKPKPIVRAPQFPPPPEGISKSQWKKICRKKRFEETRAEYAQIRKEKRNRAKLARREKLKEYTDRGEEIPEELKRPPKVNLNQSDSGISIILDCSFDDLMNDREIVSLSTQVTRAYSSNKRENNYAKIKVTSFDKRLKQRFDNDLSNSNYTKWKNFEFTADPTLPTENAVYLTADTEEKLDTLEPGTTYIVGGIVDKNRHKNLCYNKAKELNIPTKRLPIGEFINLAGRKVLTTSHMVQLMLRYFDNKDWKEAFESVLPPRKLEVDSTKEDSETASAE
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.
What are the official names of this protein?
tRNA (guanine(9)-N1)-methyltransferase, tRNA methyltransferase 10, tRNA(m1G9)-methyltransferase, tRNA(m1G9)MTase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VATL1_SCHPO
Sequence: MSTDLCPVYAPFFGVMGCTAAIVFASFGAAYGTAKAGVGISAMGVLRPDLIVKNTIPVVMAGIIAIYGLVVSVLISGNLKQILSLYSGFIQLGAGLSVGLAGLAAGFAIGIVGDAGVRGTAQQPRLFVAMILILIFAEVLGLYGLIVALLLNTRATDNVTC
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit c, V-ATPase subunit c, V-type proton ATPase 16 kDa proteolipid subunit, V-ATPase 16 kDa proteolipid subunit, Vacuolar proton pump c subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: VORB_PYRHO
Sequence: MEIPEEVKKRLTIPFEENFFAGHTACQGCGASLGLRYVLKAYGRKTIVVIPACCSTIIAGPWPYSALNANLFHTAFATTGAVISGIEAGLKALGYKVKGEDGIMVVGWAGDGGTADIGLQALSGFIERGHDAVYIMYDNEAYMNTGIQRSSSTPYGAWTTNTPGGKRHLLEKRHKKKVIDIVIAHRIPYAATASVAYPEDFIRKLKKAQKIPGPSFIQLFAPCPTGWRAPTDKSIEIARLAVQTAYFPLFEYENGKYKINMPNPKKEPKPIEEFLKLQGRFKYMTKEDVEALQKWVLEEWERLKKLAEVFG
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorB, VOR, 2-oxoisovalerate ferredoxin reductase subunit beta, 2-oxoisovalerate oxidoreductase beta chain.
Protein: ADA1B_HUMAN
Sequence: MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
What is the function of this protein?
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Its effect is mediated by G(q) and G(11) proteins.  Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
What are the official names of this protein?
Alpha-1B adrenergic receptor, Alpha-1B adrenoreceptor, Alpha-1B adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane, caveola. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK- mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
Protein: HIS7_KLUMA
Sequence: MTYPERKAFVSRITNETKIQIAISLHGGHISIPNSILDRPESDVAKQATGSQIIDIQTGIGFLDHMIHALAKHSGWSLIVECIGDLHIDDHHTTEDWGFGSRTGFKEALGHVRGVRRFGTGFAPLDEALSRAVVDLSNRPFAVIDLGLKREKIGDLSCEMIPHFLESFAEAARVTLHVDCLRGFNDHHRSESAFKALAVAIREAISSNGTNDVPSTKGVLM
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: TP20L_ARATH
Sequence: MEAITKNGSLSQTLVHCGPKSLSSFIPVRCLRFSKNPFPKKLVVTRARTSINSDHEAANRPLFQFPPSLLDDRFLSISANQSEIDSLGRDIEALKAKVSEKLVCMDVKERIHLIHLLVSLGVAYHFEKQIEEFLKVDFENVEDMNLGEEDMYSISVIFRVFRLYRHKLSSDVFNRFKEENGDFKKCLLDDVRGMLSFYEASYFGTNTEEILDEAMGFTRKHLELFVGGSNEEHLSGHIKNVLYLSQQENAEVVMSREYIQFYEQETHHDETLLKFAKINFKFMQLHYVQELQTIVKWWKELDLESKIPNYYRVRAVECLYWAMAVYMEPQYSVARIILSKSLVLWTIIDDLYDAYCTLPEAIAFTENMERWETDAKDMPDHMKVLMRSFIDLHEDFKREVILEGRLYSVEYGIDECKRLFREDLKLSKWARTGYIPNYDEYMEVGIVTAGIDMTVAFAFIGMGEAGKEAFDWIRSRPKFIQTLDIKGRLRDDVATYKDEMARGEIATGINCYMKQYKVTEEEAFLEFHRRIKHTSKLVNEEYFKTTVPLKLVRIAFNVGRAIDTNYKHGDGLTYGGIVEGQITSLFLDLITI
What is the function of this protein?
Involved in the biosynthesis of diterpenes in roots.  Possesses dolabella-3,7-dien-18-ol synthase activity and dolathalia-3,7,11-triene synthase activity in vitro.  Catalyzes the formation of dolabella-3,7-dien-18-ol and dolathalia-3,7,11-triene from geranygeranyl diphosphate (GGPP).  Does not seem to be involved in sesquiterpene biosynthesis.
What are the official names of this protein?
Bifunctional dolabella-3,7-dien-18-ol synthase/dolathalia-3,7,11-triene synthase TPS20, chloroplastic, Terpenoid synthase 20, AtTPS20.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TX32E_CYRHA
Sequence: MKLCAVIIASLLVCVAVASSSDNQKEFAQEKEMTREETQSLGEHEKDDEVTGSEERSCIEEWKTCENDCECCGMSTLCAASWVDGHQIKLCRNEGGKLKKVLHFIQKSVSKIKSCRK
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XV-5, HNTX-XV-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 02 subfamily. HNTX-XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYMM_TAKRU
Sequence: MRTRFLFLTSGCKAVPELHKIVLANAAPVKNPEIRYASTENRNYYITTPIFYVNASPHLGHLYSAVIADCFHRHKQLQGFNSRFATGTDEHGLKIQQAAEAAGKEPLEFCTTVSERFRHLFSSCNISNTDYIRTTEQRHHRAVQHFWSVLCSKGLIYKGSYEGWYSTQDESFLTPSQVTTALDSTGKEIKVSLESGHKVEWMKEENYMFRLSGFRSQLLDWLRENPRAIQPERFHHSVLQWLQEELPDLSVSRQKSRLQWGIPVPEDDGQTIYVWLDALVNYLTVVGYPNNHERWWNVAHHIIGKDILKFHAIYWPSFLLGAGLPLPQTIHVHSHWTVAGKKMSKSLGNVIDPQERSQLFTTDGLRYFLLRQGVPDTDCDYRDDKVVKLLNAELADALGGLLNRCTATALNPAQVYASFCPDSFPRERGGRADDDDYRMLESVRHLPAVVEQHFEDMHVYKALEAVSTCVRQTNGFVQRHAPWKLDRKDSADQRWLGTIIHVSLECLRIYGTLLQPVVPEISNKLLSRLGVQPHERSWTNLNFLPRFEGKDCPFEGRALGSDSGVLFSRLESQRADQQKNRKMEKGSNLK
What are the official names of this protein?
Methionine--tRNA ligase, mitochondrial, Methionyl-tRNA synthetase 2, Mitochondrial methionyl-tRNA synthetase, MtMetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.