PharMolix/UniProtQA huggingface dataset:
Protein: VLP15_BORHE
Sequence: MRKRISAIIMTLFMVLVSCNSGGVAEDPKTVYLTSIANLGKGFLDVFVTFGDMVTGAFGIKADTKKSDIGKYFTDIEKTMTSVKKKLQDEVVKNGNYAKVKTVVAKFIEEVLDKIAAGAKEAAKGATGSDAIGNAVHNQDAVAADATSVNALVKGIGEIVEVVLKDGEGDAGATKTGDTEKKSIGKLFAKKDDDRAQEAEASAANASIGAVSGADILKAIAKSGEIADNNKNIEEAKDAASIAAAKQTDDKKEIKDEAAKKDAVIAAGIALRAMAKGGKFTAKQNEEKSANAVNGAAASAVGKTLSTLIIAIRNTVDSGLKTINEALATVKQEDKSVEATNTAEATTSGQQAKN
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 15/16.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Delta subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GPMI_GEOTN
Sequence: MSKRPVALIILDGFALREETYGNAVAQANKPNFDRYWNEYPHATLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWERVEKAYRAMVYGEGPTYRDPLECIEDSYKNGIYDEFVLPSVIVREDGSPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKNLFFVCLTHFSETVKGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEKFPGEDRILINSPKVATYDLKPEMSAYEVTEALLKEIAADKYDAIILNYANPDMVGHSGMLEPTIKAVEAVDECLGKVVDAILEKGGIAIITADHGNADEVLTPEGKPQTAHTTNPVPVIVTKHGIELRKDGILGDLAPTMLDLLGLPQPKEMTGKTLIVK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CLC87_CAEBR
Sequence: MRFFRFLVFPVIAGLSSVLAAPITSNDTVDGSGEAPETLLQNSEEQPHQRLKFYNWDYKDLGTTAFEDISFPARQPPVAVNQSEQCPDGWLRFADSCYWIETELMGFAKAERKCFEKQSTLFVANSLEEWDSIRSHSKEAYFSWIGLVRFTHYEKSEQLPRWQTEGAINPTKMNWLIKPYKPIVNGWTSFANCAASYKSPATLESASYTFFYPCTYLLYSICERNSTIVNVMQ
What are the official names of this protein?
C-type lectin domain-containing protein 87, Chondroitin proteoglycan 5.
Protein: COFB_DICDI
Sequence: MSSGIALAPNCVSTFNDLKLGRKYGGIIYRISDDSKEIIVDSTLPAGCSFDEFTKCLPENECRYVVLDYQYKEEGAQKSKICFVAWCPDTANIKKKMMATSSKDSLRKACVGIQVEIQGTDASEVKDSCFYEKCTKI
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  It is the major component of intranuclear and cytoplasmic actin rods (By similarity).
What are the official names of this protein?
Cofilin-1B.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton.
Protein: YVPX_LDV
Sequence: VFRNRSSVLVEQHGKVLLQGQPIEVKTVVLDGVKAVRAKTVPAEKWEA
What are the official names of this protein?
Uncharacterized protein in VpX 5'region.
Protein: HIT1_YEAST
Sequence: MVSSAVKCGICRGVDGKYKCPKCGVRYCSLKCYKDAAKHVHKESEQPRAGTEANVEVVNNDKIINSSLAMNKTLKTKAFDDIYQNSAELQELLKYNTVKFHLAKVYRILSSTVNDGSSGKMNSDLQKELAVNYLNTLRYGGIHYNEAIEEFCQILLDKLNAVKK
What are the official names of this protein?
Protein HIT1.
Protein: HEX1_CANAX
Sequence: MVLDKMIIFHLLLWLCNVVVHAAKVEILPAPQSVTWENDTAIIINPRLLQANTSCPLLEDAFVRTVSAIEKSKWHPFPIDDFNTANGKNIKTSLVHIQVDDATVDLQLGVNESYTLKINTDGINIHAATTWGALHGLVSLQQLIIHTSEDKYVVPSSVTISDFPNFKHRGLMIDSGRNFLTVDSILEQIDIMALSKMNSLHWHLADSQSWPVALESYPHMIKDAYSNDEVYSKNDLKYIVDYARARGVRVIPEIDMPGHARAGWKQVDPTIVECADAFWTDAAVEPPPGQLNIESEKTYEVISNVYNELSDIFIDDVFHVGNDELQEKCYSAQLSPNNTVTDLLKRYLKKALPIFNKVNHRKLTMWDDVLLSDVSADKIPSNITLQVWHEISGVKNLTSRGYDVVVSSSDFLYLDCGNAGWVTNDPRYVETPENVDFNTGQGGSWCGPYKSYQRIYNFDFTANLTETEKNHVLGREAALWSEQVDSTVLTTKIWPRTAALAELTWSGNKDSNGHHRGYEFTQRILNFREYLVKLGYGVSPLVPKYCLLNPHACDLYKNPPVY
What is the function of this protein?
Has a broad substrate specificity.
What are the official names of this protein?
Beta-hexosaminidase, Beta-GlcNAcase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
Protein: TKT1_ALIF1
Sequence: MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGYDLSIEDLKNFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDSDAINAAIEAAKADPRPSLICTKTVIGFGSPNKQGTHDCHGAPLGAEEIAATKAQLGWEYGAFDIPADVYAGWDAKEVGAEKEAAWNAKFDAYAAAHPELAAEYKRRVNGDLPAEWEEKANTIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSSLIFSRQNLAQQERTQEQVADIAKGAYILKDCEGQPELILIATGSEVELAVEAAAQLTAEGKAVRVVSMPSTDAFDKQDEGYREAVFPSAVTKRIAIEAGIADFWYKYVGFGGKIIGMTTFGESAPADELFKMFGFTTENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: S14L3_HUMAN
Sequence: MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDKELTPV
What is the function of this protein?
Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
What are the official names of this protein?
SEC14-like protein 3, Tocopherol-associated protein 2.
Protein: NUOB_BLOFL
Sequence: MKYTLTLARTNQDDDSVYPEQDQKPVADPLDKQIEKNVYFGKLKNLLHKAVNWGRSNSLWPYNFGLSCCYVEMTTAFTAVHDVARFGSEVLRSSPRQSDFMVIAGTPFLKMVPIIQRLYDQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDIYIPGCPPRPEAYIQALLLLKKSINKERRPLSWVIDDQGVYKMNMKSERELKRKDRISAVEFSDTD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPMA_SODGM
Sequence: MAVTKLVLIRHGESQWNNENRFTGWTDVDLSDKGLTEAKQAGQVLKADGYVFDFAYTSVLKRAIHTLWGVLDELDQAWLPVEKSWRLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAITPPELTREDERFPGHDPRYANLSAAELPTTESLALTIDRVIPYWNETILPRMKSGERIIIAAHGNSIRAMVKFLDNLSEEEILELNIPTGVPLVYEFDDNMKPIKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RIMP_LEPBP
Sequence: MVYTEENIRELILRVLAPPLALFSLQVQNRKNHALIEIELDHLTDKTGSASLEDCETVSRRLKEELDQWGEEFDFTLQVSSAGAERVLRLPEDLIRFQGLLVKLEVPLESGKWDKRLYRLGPVSGDSVELTLYDRKTRHKKNQKSVSMPIAEIRKGNLYLEI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_BACMK
Sequence: MPKQKTHRGAAKRFKKTGSGKLKRSHAYTSHLFANKSTKAKRKLRKAGVVSAGDFKRIRQMLDNLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: VP26A_BOVIN
Sequence: MSFLGGFFGPICEIDVVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQASAEQPEM
What is the function of this protein?
Acts as component of the retromer cargo-selective complex (CSC).  The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.  The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.  The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins.  The CSC complex seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5.  Required for retrograde transport of lysosomal enzyme receptor IGF2R.  Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).  Required for the endosomal localization of WASHC2 (indicative for the WASH complex).  Required for the endosomal localization of TBC1D5.  Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP.  Involved in retromer-independent lysosomal sorting of F2R.  Involved in recycling of ADRB2.  Acts redundantly with VSP26B in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1.  Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26A, Vesicle protein sorting 26A.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome. Note=Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes.
Protein: AROC_BURO1
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMGLTEADIQIELDRRKPGTSRHVTQRQEADEVEILSGVFEGVTTGTPIALLIRNTDQRSKDYGNIVETFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPIVGAGAVAKKWLRERFGVEVRGYMSGLGEIDVPFVDWSHVHENPFFSPNAAVVPELEAYMDALRKDGDSIGARIDVVASGVPVGWGEPVFDRLDADIAKAMMSINAVKGVEIGAGFDSVAQRGSVHGDELTPAGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITKSGDEATVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVETSTPKIAGSAT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HIS4_CERS4
Sequence: MILYPAIDLKDGQCVRLLRGEMEAATVFGDDPAAQAAAFEAAGCEWVHLVDLNGAFAGRPVNAAAVEAILARIAVPAQLGGGIRDMATIALWLEKGLARVILGTVAVENPGLVREAARAFPGRVAVGIDARKGRVATKGWATETDVMATDLARSFEDAGVAAIIYTDIDRDGAMAGPNIEATDALARAVSIPVIASGGVSSLADLLALRDTGSIAGAISGRALYDGALDLTQALQALRA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_GEOMG
Sequence: MSEKTAVLLLQMGGPDSLDAVEPFLVNLFSDRDIIRIGPAFLQPFIARLIAKKRATPVERKYEEIGGKSPIRELTEAQAKALEEVLGDGYCCFTAMRYWKPTTVEALAAIRREGITRIIALSLYPHYSRATTGSSVNELKRVLAQSGATFDVTYVDRFFDHPRYIEALAEKIKEGLDDFHPLAEVQILFSAHSLPQSFIDEGDPYLSHIEETVRLVMERFEGVTYHLAFQSRAGPVKWLEPSTEEILEYLAAHQVKNLLMVPLSFVSDHIETLHEIDIEYAMLAHRLGYAKFRRSPSLNTSPLFIDCLADLVRKAGM
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_ECOUT
Sequence: MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVVVNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMLDARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: Y4RN_SINFN
Sequence: MERQISYRSLSKIPGLFSLLLAATLSRLAGRMFVLTLVLFALARFSSPVLAGWLTFAAIVPGLIVSPLAGVLLDCVGPTIAVRIDMIASTAFITAISLAGWLGWSSPPVVCTLAMLFSLAGPLGIAGIRTLLPRLVPPHALDQANALDTAVYSIVDVVGPAMAGGLVGWLGPEAAMSLIAAACAGAAVCLSQVQRLPGLASSRTSLLRQAIKGIYVVVRQPTLRGLAVSQSLYQMTWGALHVVIPVFVAGNYTVAAGSTVVGLLWALVGIAGGVGALLAGHLCTTGRERHIMTAGMAVTAFATWPIAAEFGFRGLTIGLLLAGAMSGPIDVAMLTLRQRRTNPRQLGRVMSISISVNQAGFPLGAAIAGVVITESLSAIFVLAGITSVLAAIATLSIPPDATPVA
What are the official names of this protein?
Uncharacterized MFS-type transporter y4rN.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL30_STRR6
Sequence: MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIRGMITAVSHLVTVEEVN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CYB_AMICA
Sequence: MATIRKTHPLISIINGAFIDLPAPVNISVWWNFGSLLGLCLITQIVTGLFLAMHFTSDISLAFSSVAHICRDVNYGWFLRNIHANGASLFFICLYLHIARGLYYGSYLYKETWNVGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDTLVQWIWGGFSVDNATLTRFFTFHFLFPFVIAGASMIHLLFLHETGSNNPLGLNSNVDKITFHPYFSYKDLLGFIILLAGLMFLTLFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILMIVPITHTSKQRSSTFRPLTQILFWTLVADMFILTWIGGQPVEHPFIIIGQIASIIYFALFLVFAPLAGWVENKMLSW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPE2_METCA
Sequence: MGQTASRLLTVEIVDVCREIFSGRCSRVVAPAADGEVGVLPRHTPFLTRLRPGEIRLRTEAGEDQYFYLSGGYMEVQRWEVSILADQVLRSQEIDREAALAAKRNAERMLRENRIPGERDRAYLELLKALAQLRLLERLNARKMGRNRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain 2, ATP synthase F1 sector epsilon subunit 2, F-ATPase epsilon subunit 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHS_RUEPO
Sequence: MSERLSEETRGPLLGPLFANGWAMVDGRDAIAKTFAFDNFVEAMGWMMRVAIWAEKWNHHPEWSNVYGKVAVVLTTHDVDGLSALDAKLARKMDSLC
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RL29_KOSOT
Sequence: MKATELQKFTDEELKQMLDDLKRKLMDLRFQLEMNKLTNTSQIKFVKRDIARIKTILRGRELGVRR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CM315_CONRE
Sequence: RVLLTICLLLFPLTAIPLGGDQPAERMRNVRSAVQDPRFDSVGWCCPIQGCILGCTPCC
What are the official names of this protein?
Conotoxin reg3.15, Rg3.15.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNW_BACC1
Sequence: MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQDVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNVVEVEKILQQDKEITHIAIVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPIITSFIYPEEWFDFEQLYNELKRDGFVIYPGKISKVDTFRIGNIGDVHEADINRLVDSIAKGVVIG
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: MAN2_YEAST
Sequence: MTKSDETTATSLNAKTLKSFESTLPIPTYPREGVKQGIVHLGVGAFHRSHLAVFMHRLMQEHHLKDWSICGVGLMKADALMRDAMKAQDCLYTLVERGIKDTNAYIVGSITAYMYAPDDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEIINDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAKLKKDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLEDNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAGYTYIHEVVNDPTINKYIRVLMREEVIPLLPKVPGVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMPKYVLPSIYEQLRKPDGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVKGGKDPHELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEILDQV
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: DIDH_COMTE
Sequence: MSIIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAEVIADLSTAEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVLGNVVSVNYFGATELMDAFLPALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGGIDAVMRPTQF
What is the function of this protein?
Catalyzes the reversible interconversion of hydroxy and oxo groups at position 3 of the steroid nucleus.  Along with the 3 alpha-hydroxysteroid dehydrogenase and 3-oxo-reductase activities towards a variety of cis or trans fused A/B ring steroids, it also reduces several xenobiotic carbonyl compounds, including a metyrapone-based class of insecticides, to the respective alcohol metabolites.  No detectable activity on testosterone, progesterone or 3-oxo-desogestrel.
What are the official names of this protein?
3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase, 3-alpha-HSD, 3-alpha-hydroxysteroid dehydrogenase/3-oxosteroid reductase, HSD28, Hydroxyprostaglandin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG11_MYCTU
Sequence: MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
What is the function of this protein?
Induces maturation and activation of human dendritic cells (DCs), via TLR2-dependent activation of ERK1/2, p38 MAPK, and NF-kappa-B signaling pathways, and enhances the ability of DCs to stimulate CD4(+) T cells.  By activating DCs, could potentially contribute to the initiation of innate immune responses during tuberculosis infection and hence regulate the clinical course of tuberculosis (PubMed:20176745).  Involved in resistance to oxidative stress, via TLR2-dependent activation of the PI3K-ERK1/2-NF-kappa-B signaling pathway and expression of COX-2 and Bcl2.  Also abolishes H(2)O(2)-triggered activation of p38 MAPK (PubMed:20558725).
What are the official names of this protein?
PE-PGRS family protein PE_PGRS11, PE-PGRS phosphoglycerate mutase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface.
Protein: GATA_EHRRW
Sequence: MKDILKLSIAEMHENLIKKEFSAVELTQTHIDAINNEQLNAFITKTPEVALDAARKADHILIHEQDKITPLTGIPVGIKDLFCTKNIKTTACSNILRNFTPQYDSTVVKRLIDDGAVMLGKLNMDEFAMGSSNSNSCFGPVENPWTRADGVKVVPGGSSGGSSAAVAGFLCAGALGSDTGGSVRQPAAFCGIVGLKPTYGRCSRLGMIAFASSLDQAGVLTRTVKDAALMLQPICGYDTQDSTSANITTPRFLDSITNIIKGKRIGIPKEYELSDKYKEYEEVSEMWLKGIKYLENEGAEIVNISLPHTSYALPVYYIICSAEASSNLARYDGIKYGTRVNSDNINEMYELTRGNNLGTEVKRRILIGAYALSSGYYDAYYNKAQCIRRLVTNDFVESFKSVDYILTPTAPKEAFAMDEQLDTLTMYLNDVFTVPASLAGLPAISIPIGLSKNKLPLSLQIIGNYYDEGGILNIASVIEKHTGNILK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.