PharMolix/UniProtQA huggingface dataset:
Protein: DSBB_LEGPL
Sequence: MKKLTYRKIQSFQAIITVLVIFASFYLEYAAGLQPCPLCLMQRVCVFILLGLMGVSLGTVKKAHIVSLIQFQVACAGLYFSLRQLWLQSLPSDQAPACMPGLDVLIQYFPWQTVAKALFWGAGDCAEVTWTMFGVSMPGWAAMYFLSMAIMGLFLFFRTRTIN
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YNFA_ECO5E
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGPLIALCGMLIIVVGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRM61_CANAL
Sequence: MSFFQYKNYIEEGDLVLAYISRSTIKPINVKKGEIFNTRYGHFEHDKMIGMKYGEQMPGAKGYGFIHLLHPTPELWTLSLPHRTQIVYSPDSSYIIQRLNVKPGSRVIEAGTGSASFTHSFARTVTLSGKVFTYEFHEPRYLEAKKELEEHKLDNTTITHRDVCNDGFSIDNESIEGDVVFLDLPSPWDAIPHLDSVISTSKAAGICCFSPCIEQVDRTVRALEENGWTEIEIVEVAAKRWSARKEMVRSVADAVQRIREIQNGRKTGLEVMKKGPSEEPPAKLQKTDNGYKTPKKSTKVKEGDENYTWLNATKSESEIKSHTSYLTFACKIPKQ
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA(m1A58)-methyltransferase subunit TRM61, tRNA(m1A58)MTase subunit TRM61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WTR16_ARATH
Sequence: MEWPWSAIAASSSSSSSCFFASPNSCLSITRRTNLSCVNTSVKSLRHSRFDSKHNLVKRRINGDSVVRRSTTSNNSTEETESSSSSSSVDCVGMGSDVECVNNGEDEENRSSGILSGGEGTFLEWTVLISPFFFWGTAMVAMKEVLPITGPFFVAAFRLIPAGLLLVAFAVYKGRPLPEGINAWFSIALFALVDATCFQGFLAQGLQRTSAGLGSVIIDSQPLTVAVLASFLFGESIGIVRAGGLLLGVAGLLLLEVPSVTSDGNNFSLWGSGEWWMLLAAQSMAIGTVMVRWVSKYSDPIMATGWHMVIGGLPLLAISVINHDPVFNGSLQDLSTNDVIALLYTSIFGSAVSYGVYFYSATKGSLTKLSSLTFLTPMFASIFGYLYLNETFSSLQLVGAAVTLVAIYLVNFPEGND
What are the official names of this protein?
WAT1-related protein At3g02690, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: Y1989_BEUC1
Sequence: MSGHSKWATTKHKKAVIDARRGKLFAKLIKNIEVAARTGGGDPAGNPTLYDAIQKAKKTSVPNDNIDRAVKRGAGLEAGGADYQTIMYEGYAPGGVAVLVECLTDNRNRAASDVRVAFTRNGGSLADPGSVSYLFSRRGVVVVPKTDGLDEDDVLGAVLDAGAEEVNDLGEAFEVLSEATDLVAVRTALQDAGLDYDSAEAQFVPATQIEVDVDGARKVLRLIDALEDSDDVQNVFANFDATDEVLAQLDED
What are the official names of this protein?
Probable transcriptional regulatory protein Bcav_1989.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNB2_ADEG1
Sequence: MERTPKRAHGFRSTKPVKRTAEVMMEEEEEEVEVVAPGRGATRKKVSRREESPSPVRRVTRRRETVVDDEENASDEESPEAPLSDPVVYGAQRAMATVASICEALDLQWQGASVRPDDSIWTKMGGTYVRKKHPEFRLTFSSYDSFNAQVGRFLAAVIYSRAGLEPKFVPGGAHVWRHGWFPALQEPFPKCMHGVDMVTKPRTVELNPSSEAGKRALAEQNGVIEKNRFGRQVVVLRFDANAVCYKDQEHSGFPHPHAHGSCAMVFSDAAKAVSAMRHDIDWTKALYPNADKRRAEECVLISTNCNCNYASDRAISGRQFCKMTPYKLNGTDDITRDMVESRPDMKAHKKNPHTMVFTCCNPQAASGGAGRGLKKTEKTCAWRLSAMDLRYAYVFATELFTAVMGSSEPTHVPEFRWNESYAFKTEVLAPVSPIASDDPFA
What is the function of this protein?
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers.  Also enhances the rate of initiation.  Released from template upon second strand synthesis.  Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication.  Covers the whole ssDNA genome during synthesis.  The complementary strand synthesis induces its relese from DNA template.  May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
What are the official names of this protein?
DNA-binding protein, DBP, Early 2A protein, Early E2A DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E2A DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Accumulates in infected cells.
Protein: ERPA_HAEI8
Sequence: MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLIGGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: AMPD_ENTCL
Sequence: MLLENGWLVDARHVPSPHHDCRPEDEKPTLLVVHNISLPPGEFGGPWIDALFTGTIDPDAHPFFAEIAHLALSADCLIRRDGEVVQYVPFDKRAWHAGVSMYQGRERCNDFSIGIELEGTDTTPYTDAQYEKLVAVTQTLIGRYPAIADNITGHSDIAPERKTDPGPAFDWSRFHAMLTTSSDKEIT
What is the function of this protein?
Involved in cell wall peptidoglycan recycling.  Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety.
What are the official names of this protein?
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD, N-acetylmuramoyl-L-alanine amidase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CLOTE
Sequence: MQNKVHVRKQDTVMVISGKDKGKIGEVLRVLPKSGKVVVKDVNVVTKHQKPSRENMQGGIIHVEAPIYSSKVMLYCTKCKSVTRINHKILDDGTKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: FOXL2_ELLLU
Sequence: MMASYPEPEDAAGALLAPENGRTVKEPEAPPPSPGKGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGSGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPSSPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
What is the function of this protein?
Transcriptional regulator.  Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity).  Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity).  Has apoptotic activity in ovarian cells (By similarity).  Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity).  Activates SIRT1 transcription under cellular stress conditions (By similarity).  Activates transcription of OSR2 (By similarity).  Is a regulator of CYP19 expression (By similarity).  Is a transcriptional repressor of STAR (By similarity).  Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity).
What are the official names of this protein?
Forkhead box protein L2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YG63_SCHPO
Sequence: MDDPNSYDVIIVGTNLRNSILSAALSWANQRVLHIDENSFYGEIDGSLTLRDLEQINEKIKKVDSSQILNDNGSHKSPLKRFEVQFLNKDLIPKNKGSVIQFHPQEIFASSELVKLLSETKIYKYLLLKPARSFRLLTSNEEWIKVPESRADIFNNKNLSLASKRIVMRFMKFVSNIADEQNQNLVKEWESKPFYKFLEEVFQLSGAIEESIIYGLCQSLSKDIPTKDALDTVLKYFHSFGMYGDYSYLLAMYGTGSELCQGFCRSSAVMGGTFMLGQAIDKIDESKIVLKDGSTLSAKKIVSSVDEGKLPHQQIQQRYLLVKGDCQQLFQEDGFFAALDASLIHFSPFSISENFGNSVQAKLYGSGSGDCPEGYCIWYLKTLNDSPCNEVFNLATKKLCSFSGCDDLEIIVQVDETLNQLRHIDYDDTLHSAKSLFYEILGQNNTFLQREGLFDEDDE
What are the official names of this protein?
Uncharacterized Rab geranylgeranyltransferase C15C4.03.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TMN3_YEAST
Sequence: MRVRPKRSVITLMAIVVVMLILRNQFYSSRTRGHGQEPVISSSQKNLYDGWITPNFYRKGDPLELIVNKVESDLTQLPYAYYDLPFTCPPTMHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLCARKTTKEGMQTLDKLVREGYVVQWLIDDELPAATTFISTTDHKKYYASGFPLGFIDPDTDKTYLHNHVMLVIRFHASDNDKNTIVGFEVYPRSVSDYHCPGASKNYEQYEIVIPEDENELTYLPFTYSVYWREEFEVDWNHRWDYFLNAGELSDEQSIQFHWMSLANSVGIVLSISFITLIIYVRVMYTDKSNSKSPKYMINIEGIETEDDLDDDKYGKYSVYTVAKDWIQNGRPNLFGLKVLILLVSFGVQFLFTIIGSLTISCSMNKLHNVRNSVLTMAILFFVLGAFMASFVGTRLSMVTKTKRTKANYLDDNRYLKDYKKFSPIFTILCGSSLPGIVMVSTFLLNSIVWAHDSTSALPFKTIVFFMSIYFIVCIPLSLFGGIVANNIPLPQYWLSGITKDESNSDGNGLFVPKSRAKFNPLVYCGIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFYGFLFLSIILLCVLTMEISIIGSYLLMRFCFEDKVVRNNWRWKCFEMGFSGGVYMELYSLYYIFAVLNIHGFSSILISICYSLIFNVMCSLGLGALSYLTASWFINKIYHQKVNL
What is the function of this protein?
With EMP70 and TMN2, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression.  Acts downstream of RAS2 and TOR.  Essential for cell adhesion and filamentous growth.  May play a role as effector of cellular copper homeostasis.
What are the official names of this protein?
Transmembrane 9 superfamily member 3.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RUS4_ARATH
Sequence: MHSTNQSSRLFQYPCKSTSTQYPIFIFPKFSSRKFVKSLRTSIDYKQEGASKEDLVVPSNVARRLPIIIKKSGKVSRYFIKGDSLELLCVDEEEDDSTSFCLGLDDGFWKLIRLTSSAAKDFFLPKQVSDNYISYVKWKFLHRVFSSALQVLATQAMFRAIGIGQSRSLASSAAFNWILKDGLGRLSRCIYTASLASAFDTNLKRVRFSTSVLFSLSIGVELMTPVFPQYFLLLASIANIAKQISLSCYLATGSAVHRSFAVADNLGEVSAKAQIQTVCFDNLGLLLAVLLNMLFQHNQRLQACLPFVLYPIFSTFDLLGIYQGLKHINLQTLTKDRLEIILERWIEFRQVPSPAEVSEEEGIGLLGSRGSKRVWPIRIGCLDPKAQIPTLSMMAMQSLCSDDGYFITMELSSQGFRRIPKSGIVICLREGANSVDVITSLLQTCYIRKSLGANRTKRSYLSFSDLTLQDWTLLTRESKRAARDDNIALNKQMQEQGWIVKNVLLSAEEQIRYIFDKNQL
What are the official names of this protein?
Protein root UVB sensitive 4.
What is the protein family that this protein belongs to?
Belongs to the RUS1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LUTA_BACAH
Sequence: MKVTLFVTCLVDMFETNVGKATVEVLERLGCEIEFPEAQVCCGQPAYNSGHVEAAKEAMKHMIETFEDAEYIVTPSGSCATMFHEYPHVFKDDPKWAKRAQKVADKTYEFTQFIVDVLKVTDVGASLPGIATIHKSCHMTRMLGVTEAPGILLSNVKGLTVRELPNVQNCCGFGGTFSVKMTPISEQMVDEKVDSAMETGADYLIGADCGCLLNIGGRIERLGKEIKVMHIAEVLNSRS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: TLCD_RICTY
Sequence: MTINASNIENSFSKINSHFSKLTDYIWPIKRNEISKFLFITLLMFCILFIQNLIRALKDSIVTTMIGAETISFLKFWGVMPSAFLITVMYVKLVNRMKAENIFYLIISIFLIFFALFAYVIFPNHEILHLRPVTVHNLTTSLPNLKWFILLLSKWSFSLFYIIAELWPNVVFALLFWQFVNNITTVEESKRFYPLFGLLSQTGIYLAGHFLENLSKINYYITDKFALQSSFHTLSIQIILTIVLILGIVSIKTFWLLNHKVLDKKHMSLLRFKTKNKSITIAKSFQMILSSRHIRLIATLLICYGIAINLVEGPWKAAATKIYKTPTEYAAFIGSYLSYTGVFTIFFVLLGSNIVRRIGWFTSAVITPSIVFITGILFFAFNNFEGFAGLIIANFILTDPALVAITIGAIQNVLSKSSKYTLFDSTKEMAYVPLEPEIKISGKAAADVIGTKLGKSGSAFLQSLIFIILPSSSYQSISICLMIIFILTCLTWIWATKELNKEYKNSIKFSQK
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 4, ADP/ATP translocase 4.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDD_METNO
Sequence: MSLPRRAAHVAIRGYQLTLSGLVGRQCRHWPSCSAYTDEAIERHGLWAGGWMGLARICRCGPFGTHGIDLVPERLPEGAAWHRPWAYGRWRGVNAPATPLAEEVHDPLPGP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PGAP3_XENTR
Sequence: MAPFLVLFLAGVVAASRGDREPVYRDCVTLCERNNCTGSRLTDFRAEQPLYMRVTGWTCLDDCRYQCMWYTVSLYLKEGHEVPQFHGKWPFSRFLFFQEPASALASFLNGVASLLMLLRYRSSVPSSCQMYRTCLAFSMVSVNAWFWSTIFHTRDTALTEKMDYFCASSVILHSIYLCCMRTFGLQYPSIANGFGAFLVLLFACHVSYLTLGRFDYSYNMAANTGFGVLNLMWWLAWCFRRRFHQPYLWKCVLVVISLQSLALLELLDFPPVMWILDAHALWHFSTVPLHFLFYSFLKDDSLYLLKINHDDIPKLD
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.
What are the official names of this protein?
Post-GPI attachment to proteins factor 3, PER1-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PGAP3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RISB_THEKO
Sequence: MEVRVIEGEFKGEGVKIGVVVARFNDLLTNELLSGALDCFERHSVEEVDVVKVPGSFEIPLVAKKLAESGKYDAVLALGAVVRGETKHFDLVANEVAKGVAKVSLDSGVPVIFGVITVEDELQGFNRAGVKSNKGFEYAMAALEMANLMKKLREKE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RECX_THET8
Sequence: MGSEALAYALRLLARKGYSRAVLRAKLAARFGEAEAEAALGRLEAMGYLDDRAYARAFVETRARRYGPRKLRALLLARGVPEEVVEEVLPEARVEEALAVLRRYRHREDKARAVRFLEGRGFPLGVALEAWRLAQEEGEGYK
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1586_MYCBO
Sequence: MYRWCMSRTNIDIDDELAAEVMRRFGLTTKRAAVDLALRRLVGSPLSREFLLGLEGVGWEGDLDDLRSDRPD
What are the official names of this protein?
Uncharacterized protein Mb1586.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2009.
Protein: CRFA_CONVC
Sequence: MSGRGFLLLALLLLVTVEATKVEKKHSGFLLAWSGPRNRFVRFGRRDMQSPLLSERLRL
What is the function of this protein?
This peptide activates human and mouse sensory neuron-specific G-protein coupled receptors MRGPRX1 (PubMed:30243794).  The activity on human receptors has been measured (EC(50)=1. 8 uM) (PubMed:30243794).  Compared with the agonist chloroquine (anti-malaria drug), it is 200-fold more potent (PubMed:30243794).  The peptide also causes an increase in cytosolic calcium in a specific subset of DRG neurons, and, in contrast to other Conus venom peptides, the peptide also affects a large fraction of the non-neuronal cells (PubMed:25464369).  In vivo, when intracranially injected into mice, it principally renders mice unable to move, and at very low doses, it causes hyperactivity (PubMed:25464369).  It also induces itch sensation, since intradermal cheek injection into humanized transgenic mouse (mouse MRGPRX1 replaced by human MRGPRX1) induces scratching (PubMed:30243794).  In vivo, when tested at high doses (10 uM) on zebrafish larvae, it induces a range of behavioral effects ranging from an early hypoactivity during the first hour of treatment to an increase in movement during the following hours when the larvae are submitted to strobe light phases (PubMed:33764053).
What are the official names of this protein?
Conorfamide-Vc1, CNF-Vc1, Cono-RFamide-Vc1.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR9_SPIOL
Sequence: MAVSISSLTSSFASLSFTSNLTPKPQTLPMARTKPFSLSNPAVVKPLVITATSATAPVEVAETADLEKFVKSRLPGGFAAQTVIGTGRRKCAIARVVLQEGTGKFIINYRDAKEYLQGNPLWLQYVKTPLATLGYETNYDVFVKAHGGGLSGQAQAISLGVARALLKVSASHRAPLKQEGLLTRDSRIVERKKPGLKKARKAPQFSKR
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic, Chloroplastic small ribosomal subunit protein uS9c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOL_BPSP6
Sequence: MQDLHAIQLQLEEEMFNGGIRRFEADQQRQIAAGSESDTAWNRRLLSELIAPMAEGIQAYKEEYEGKKGRAPRALAFLQCVENEVAAYITMKVVMDMLNTDATLQAIAMSVAERIEDQVRFSKLEGHAAKYFEKVKKSLKASRTKSYRHAHNVAVVAEKSVAEKDADFDRWEAWPKETQLQIGTTLLEILEGSVFYNGEPVFMRAMRTYGGKTIYYLQTSESVGQWISAFKEHVAQLSPAYAPCVIPPRPWRTPFNGGFHTEKVASRIRLVKGNREHVRKLTQKQMPKVYKAINALQNTQWQINKDVLAVIEEVIRLDLGYGVPSFKPLIDKENKPANPVPVEFQHLRGRELKEMLSPEQWQQFINWKGECARLYTAETKRGSKSAAVVRMVGQARKYSAFESIYFVYAMDSRSRVYVQSSTLSPQSNDLGKALLRFTEGRPVNGVEALKWFCINGANLWGWDKKTFDVRVSNVLDEEFQDMCRDIAADPLTFTQWAKADAPYEFLAWCFEYAQYLDLVDEGRADEFRTHLPVHQDGSCSGIQHYSAMLRDEVGAKAVNLKPSDAPQDIYGAVAQVVIKKNALYMDADDATTFTSGSVTLSGTELRAMASAWDSIGITRSLTKKPVMTLPYGSTRLTCRESVIDYIVDLEEKEAQKAVAEGRTANKVHPFEDDRQDYLTPGAAYNYMTALIWPSISEVVKAPIVAMKMIRQLARFAAKRNEGLMYTLPTGFILEQKIMATEMLRVRTCLMGDIKMSLQVETDIVDEAAMMGAAAPNFVHGHDASHLILTVCELVDKGVTSIAVIHDSFGTHADNTLTLRVALKGQMVAMYIDGNALQKLLEEHEVRWMVDTGIEVPEQGEFDLNEIMDSEYVFA
What is the function of this protein?
DNA-dependent RNA polymerase that catalyzes the transcription of viral genes.
What are the official names of this protein?
DNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
Protein: PHF1_CLOPA
Sequence: MKTIIINGVQFNTDEDTTILKFARDNNIDISALCFLNNCNNDINKCEICTVEVEGTGLVTACDTLIEDGMIINTNSDAVNEKIKSRISQLLDIHEFKCGPCNRRENCEFLKLVIKYKARASKPFLPKDKTEYVDERSKSLTVDRTKCLLCGRCVNACGKNTETYAMKFLNKNGKTIIGAEDEKCFDDTNCLLCGQCIIACPVAALSEKSHMDRVKNALNAPEKHVIVAMAPSVRASIGELFNMGFGVDVTGKIYTALRQLGFDKIFDINFGADMTIMEEATELVQRIENNGPFPMFTSCCPGWVRQAENYYPELLNNLSSAKSPQQIFGTASKTYYPSISGLDPKNVFTVTVMPCTSKKFEADRPQMEKDGLRDIDAVITTRELAKMIKDAKIPFAKLEDSEADPAMGEYSGAGAIFGATGGVMEAALRSAKDFAENAELEDIEYKQVRGLNGIKEAEVEINNNKYNVAVINGASNLFKFMKSGMINEKQYHFIEVMACHGGCVNGGGQPHVNPKDLEKVDIKKVRASVLYNQDEHLSKRKSHENTALVKMYQNYFGKPGEGRAHEILHFKYKK
What are the official names of this protein?
Iron hydrogenase 1, CpI, Fe-only hydrogenase, [Fe] hydrogenase.
Protein: RL18_RICPU
Sequence: MRSAKLKFEKRRSRIRHKISKTSHSVRLSIFKSGRHIYAQIIDDSKSITIAAASTLDEKIKKLKKSHCNIENAIKVGEEIAKKADSAGIQDVVFDRGGYKYHGVVKALADAAREKIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RSMF_ALIFM
Sequence: MHDNIFLPDAFLAQVQETMPSHLSMDEFIAACKRPLRRSIRVNTLKNSVEEFKQRAAEKQWDLEPVPWCDTGFWITRPESDTVKLGSTAEHMAGLFYIQEASSMMPVTALLKDNDDIEMALDMASAPGSKTTQLAAGMKNQGALVANEFSSSRVKVLCSNIQRCGVSNVALTHFDGRVFGGWLPETFDSILLDAPCSGEGTIRKDPDAMHNWSPESVIEIGDTQRDLIESAFHALKPGGVMVYSTCTLNHEENQNICHHLVEQFGDAVTFKPLGDLFENAEKALTKEGFLHIYPQIFDSEGFFVAKIRKNSSTTPPEVKKRLGKFPFAPASNKEAQAIEAELKSTLQLAIPEDNEFWIRDKEVWAFPKRMKPLIGEMRYHRIGFKLAETHKKGYRWQHEAIMALATADNPTCAELTTEQAREWYMGRDVRPDFSGKGETIVTYKGAVIGLGKWVGNRIKNGLPRELVRDGNLF
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_HELAH
Sequence: MNETLKQELLQNIREVKDYPKKGILFKDITTLLNYPKLFNKLIDALKKRYTPLNVDFIVGIEARGFILGSALAYALGVGFVPVRKKGKLPAHTLSQSYSLEYGNDSIEIHSDAFRGVKGVKVVLIDDLLATGGTALASLELIKALQAECIEACFLIGLKELLGIQLLEEQVKTFCLLEC
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_ECO27
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVIAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: GTR1_PIG
Sequence: MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWLHRYGESISPATLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFISAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNEELWPLLLSVIFIPALLQCVLLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEESRQMMREKKVTILELFRSAAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
What is the function of this protein?
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake.  Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.  Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity).  In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Photoreceptor inner segment.