PharMolix/UniProtQA huggingface dataset:
Protein: GBG5B_HUMAN
Sequence: MSGFSSVAATKKVVQQLQLEAGLNSVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVCSFL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5B.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
Protein: COX2_CTEFE
Sequence: MNTWMNFNLQNSNSPLMEQLMFFHNHSMLIILLITILVGYIMSSLLYNKLYNRYLLESQNVEIIWTILPAFMLIFIALPSLRLLYLLDDSNSPLISLKAIGHQWYWSYEYTDFNNISFDSYMIPSNELNLNSFRLLDVDNRIILPINSQIRILITATDVLHSWTIPSLGIKIDATPGRLNQSNFMMNRPGLYFGQCSEICGANHSFMPIVIESILINSFIKWISSNS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADK_PSEP1
Sequence: MEQFRNIGIIGRLGSSQVLDTIRRLKKFLLDRHLHVILEDTIAEVLPGHGLQTSTRKLLGEVCDLVIVVGGDGSLLGAARALARHNIPVLGINRGNLGFLTDIRPDELEQKVAEVLDGHYLVENRFLLQAEVRRHHEAIGQGDALNDVVLHPGKSTRMIEFEIYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDLQIYPQVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLDHNYYEVCRTKLGWGSRLGSSDD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACVL1_HUMAN
Sequence: MTLGSPRKGLLMLLMALVTQGDPVKPSRGPLVTCTCESPHCKGPTCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRRRQEKQRGLHSELGESSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVALVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASDMTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGKPAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDEQIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVCVDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNSPEKPKVIQ
What is the function of this protein?
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development.  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.  Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.  May bind activin as well.
What are the official names of this protein?
Serine/threonine-protein kinase receptor R3, SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HLYB_PROMI
Sequence: MKKKVVLLTLLSCFSTSGLSANETGNLGSISESRRALQDSQREINQLIEQNRYQQLQEKAVNISPTPTLITESEHCLPIKGVYIQGITLLTEKDLNSLSPLPDQCIKSADINRLVKELTQRYLQHGYITARIQFLRPNQHGELGLYAIEGFVERIEGGDRGVNTTLLFPRIKGQPLKLATLDQGLDQANRLQSNKVTVDILPGTELGGSVIKLSNQRKSPWHLNIASDNYGQKNSGRWLIRTNASLDSPLGLSDFVSLNANITTDNPNTRFNRAYTLLYSIPYGGFTFSSFGSYSEYQFHQKLQTRTVNLYGDTTQVGIRGDYAFSRSQKQIDTLNIQVTHKRIRNYFSQIRLDLSSPKLTTIELGINHLQIIPNGVLSTNLSVEKAVGWFGAEETPYIANGNGNDYRFTKVKLFTNWYQRFSLWHSTFLFNSTFLGQYSHDTLPGVEWLSLTDKNAIRGFDQSTLSGDNGGYLRNTLSYPYRLNHFSITPRIGVDIGQVKQHGNYKGWQGGYGLSSGLNIQYQQAQLDLEVAKGELLYHQTNSNKTKDPTQLLVKFSYLF
What is the function of this protein?
Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin.
What are the official names of this protein?
Hemolysin transporter protein HpmB.
What is the protein family that this protein belongs to?
Belongs to the TPS (TC 1.B.20) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: MNB1B_MAIZE
Sequence: MKGAKSKGAAKADAKLAVKSKGAEKPAKGRKGKAGKDPNKPKRAPSAFFVFMEEFRKEFKEKNPKNKSVAAVGKAAGDRWKSLSESDKAPYVAKANKLKLEYNKAIAAYNKGESTAAKKAPAKEEEEEDEEESDKSKSEVNDEDDEEGSEEDEDDDE
What is the function of this protein?
Recognizes an AAGG motif at the MNF1-binding site.
What are the official names of this protein?
DNA-binding protein MNB1B, HMG1-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF1C_ANEMR
Sequence: MKKQDLIDMEGVVTESLPNAMFRVCLDNGCQVLTHISGRIRRNYIRILPGDRVRVESSPYDLTKGRITYRLRAKSSTD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, plastid.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid.
Protein: DAPB_PARL1
Sequence: MTADIKIVVTGAAGRMGRTLIRLIHETEGLSLAGGLEGEGSPYLGTDLGTLAGLAQPTGLAATADALTLIKDADALIDFSVPAATLEFAALAAQARIVHVIGTTGFEVVDEEKIKAAARHATIVKAGNMSLGVNLLAALVRQAAKALDGQWDIEIVEMHHRHKVDAPSGTALLLGEAAAEGRGVALEDVSARGRDGITGARKAGDIGFASLRGGSVVGDHTVVFATEHERITLGHIAEDRSIFARGALKAARWGQGKGPGLFSMADVLGIE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39A4_HUMAN
Sequence: MASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCANGPCGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKMACVDIPQLLEEAVGAGAPGSAGGVLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGAVTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF
What is the function of this protein?
Plays an important role in cellular zinc homeostasis as a zinc transporter.  Regulated in response to zinc availability (By similarity).
What are the official names of this protein?
Zinc transporter ZIP4, Solute carrier family 39 member 4, Zrt- and Irt-like protein 4, ZIP-4.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Protein: YICG_ECOLI
Sequence: MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGGSVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSIIGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLYIALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH
What are the official names of this protein?
UPF0126 inner membrane protein YicG.
What is the protein family that this protein belongs to?
Belongs to the UPF0126 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEX3_YEAST
Sequence: MAPNQRSRSLLQRHRGKVLISLTGIAALFTTGSVVVFFVKRWLYKQQLRITEQHFIKEQIKRRFEQTQEDSLYTIYELLPVWRMVLNENDLNLDSIVTQLKDQKNQLTRAKSSESRESSPLKSKAELWNELELKSLIKLVTVTYTVSSLILLTRLQLNILTRNEYLDSAIKLTMQQENCNKLQNRFYNWVTSWWSDPEDKADDAMVMAAKKSKKEGQEVYINEQAFLSLSWWILNKGWLSYNEIITNQIEIEFDGIHPRDTLTLEEFSSRLTNIFRNTNSQIFQQNNNNLTSILLPKDSSGQEFLLSQTLDADALTSFHSNTLVFNQLVNELTQCIESTATSIVLESLINESFHFIMNKVGIKTIAKKKPGQEDQQQYQMAVFAMSMKDCCQEMLQTTAGSSHSGSVNEYLATLDSVQPLDDLSASVYSNFGVSSSFSFKP
What is the function of this protein?
Involved in peroxisome biosynthesis (PubMed:1894692).  Acts as a regulator of MSP1 by inhibiting the ability of MSP1 to unfold target proteins (PubMed:32541053).
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: TX8C_ANEVI
Sequence: LVIVFVVLLGVPLISANEEELLAILQDQRNDARGGCLNRYKSNICGTLVTPMNCITPRTRMGKFARKFCQFMCGIC
What are the official names of this protein?
U-actitoxin-Avd8c, U-AITX-Avd8c, Avtx-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone 8 toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: LEUC_XANOP
Sequence: MTAKTLYDKLWEMHEVTRRDDGSSLIYIDRHILHEVTSPQAFEGLRLAGRNPWRIDANIATPDHNVPTTRAERQGGLESISDEVSRLQVQTLDENCDDFGILEFKMNDARQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLITKKMKNLQVRVEGTLPFGVTAKDIVLAVIGKIGTAGGNGHALEFAGSAIRALSMEGRMTICNMSIEAGARVGMVAVDEKTIAYVKGRPFAPKGADWDAAVALWSTLVSDPDAHFDTVVELHAEDIKPQVSWGTSPEMVLAIDQHVPDPATEQDPTKRNSIERALKYMGLKANQAITDIRLDRVFIGSCTNSRIEDLRAAAAVAKGRKVASTIKQALVVPGSGLVKAQAEAEGLDKVFLDAGFEWREPGCSMCLAMNPDKLGSGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVSGHFVDVRELGDSGVGIRDS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CH60_BRUA1
Sequence: MAAKDVKFGRTAREKMLRGVDILADAVKVTLGPKGRNVVIEKSFGAPRITKDGVSVAKEVELEDKFENMGAQMLREVASKTNDTAGDGTTTATVLGQAIVQEGAKAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQVGTISANGEAEIGKMIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNPEKMVADLEDAYILLHEKKLSNLQALLPVLEAVVQTSKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLESVTLDMLGRAKKVSISKENTTIVDGAGQKAEIDARVGQIKQQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALNATRAAVEEGIVAGGGTALLRASTKITAKGVNADQEAGINIVRRAIQAPARQITTNAGEEASVIVGKILENTSETFGYNTANGEYGDLISLGIVDPVKVVRTALQNAASVAGLLITTEAMIAELPKKDAAPAGMPGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_CLOB6
Sequence: MDIKEIKVGIADLNVGKNPDKIITVGLGSCIGIALYDGIKCIGGLSHIMLPDSTQFSKVTNPMKFADLAIPILVEKMEKLGARKNGLKAKICGGASMFNFSDKSMVMDIGNRNGKAVKEKLKELSIPLLAEDIGGNKGRTMIFDTSTGKVYIKTVGLGTKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: FB307_ARATH
Sequence: MRTRSKKTKTVNNNNDLQKSEEKQKFDQLPLDLEIEMFRRLPLKSVARFLTLSKSCATTIRSPSFITSFPSQPCTLIASAATIRTCHNLPSSFKSKDQRLYFFSSSSSSSTVFSTRLTCPLSPYDNLIEYYYHYASGLISIGCNRKQIVTNPSTGRFITLPSVRRRRVVVKSFFGYDPVSDQYKVSCMTERRHGLRQDPSSEHQVFTLGEKKPWKMIDCTSIPDHRPWSNGVCIDGFVYYVAKTGQGMSQLSLMRYALRADNLNLFTSLPEELRTLKLSGDTLLNYEGNVAWPLQLHLIFNVWVMDQDGEKHEWLKKITFNIEPWKSSSRYLDVRGTTHTGEFILAPSHYPDDEFYVFHYNLGKNSFTKKKLQVRIYNVRIVSTSSIIGLYLSFSLL
What are the official names of this protein?
Putative F-box protein At1g26510.
Protein: CAPSD_BFDV
Sequence: MWGTSNCACAKFQIRRRYARPYRRRHIRRYRRRRRHFRRRRFTTNRVYTLRLTRQFQFKIQKQTTSVGNLIFNADYITFALDDFLQAVPNPHALNFEDYRIKLAKMEMRPTGGHYTVQSNGFGHTAVIQDSRITKFKTTADQTQDPLAPFDGAKKWFVSRGFKRLLRPKPQITIEDLTTANQSAALWLNSARTGWIPLQGGPNSAGTKVRHYGIAFSFPQPEQTITYVTKLTLYVQFRQFAPNNPST
What is the function of this protein?
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry.  This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents.  Essential for the initial attachment to heparan sulfate moieties and chondroitin sulfate B of the host cell surface proteoglycans.  After attachment, the virus is endocytosed and traffics to the nucleus.  The capsid protein binds and transports the viral genome and Rep across the nuclear envelope.
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the circoviridae capsid protein family.
What are the subcellular locations of this protein?
Host nucleus. Virion.
Protein: RPOC_METPP
Sequence: MKGLLDLFKQFTPDEHFDAIKIGLASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVVDPGMTELKKFSIMTEDDYDAKKQQHGDEFVALMGAEGIQKLLAEIDLDVEIERLRGDMTGSELKVKKNSRRLKVMEAFKKSGIKPQWMVMNVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLARLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSIEAQMEARTLMLASNNVLFPANGEPSIVPSQDVVLGLYYATRDRINAKGEGLIFSDVVEVQRALDNGQVEITAKIAVRLTEWTKDKESGEFVPESKLVDTTVGRALLSEILPKGLPFANINKALKKKEISRLINTSFRKCGLKETVVLADKLLQSGFRLATRAGISISIDDMLVPKQKHDLIERAEKEVKEIEQQYVSGLVTAGERYNKVVDIWGKTGDEVGKVMMAQLSKQKVEDRHGKLVDQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTDAGIAMRALVEGGEVIESLRDRILGRVTAIEVLHPETQQVVVPAGLMLDEDTLDIVEAAAVDEVKVRTPLTCHTRFGLCAKCYGRDLGRGGLVNAGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSDGHIGFNATMRYVTNGKGELVVISRSGEIIISDQHGRERERHKVPYGATLNIKADQQVKAGTVLANWDPLTRPIITEFAGKAKFENVEEGVTVAKQVDEVTGLSTLVVIDPKRRGAAKVVRPQVKLLDAAGNEVKIPGTDHSVTIGFPIGSLVQIRDGQDLAPGEVLARIPVEGQKTRDITGGLPRVAELFEARTPKDKGTLAEMTGTVSFGKETKGKVRLQITDPDGKVYEELVPKEKNILVHEGQVVNKGESIVDGPADPQDILRLLGIEELARYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVNPGDTHYILGEQVERASMLDTNDKMRAEGKMIATHADVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAFHRARKAKEEMDDAERRSIALQEAEEQALLTPATTAEAVVGEEPAPPPAQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ALAE_ALIF1
Sequence: MSKKGPFNIRNAAADTFAMVVFCFITGMFIEILISGMTFEQSLASRTLSIPVNIAIAWPYGVFRDFMLRQGARISPSKFMKNIADLVAYVTFQSPAYAMILLVVGATPEQIITAVSSNVVVSCVMGVFYGYFLDACRKAFKVPGYYTPQA
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAP46_ORYSJ
Sequence: MVEVEEVSNKMQAQMRLHPAAAAEEEDADLPLPALFDKASHLHSLASSSSLDQEGIRKGVDLLRRCDEMVSKLGLFSSNETKDDVSTANLKYLLVPYYLGEMTERVAQEDRIPVLKASQDHLKEFISICEALELISEDELELSRQKQPDTMANRRAQKVARFKRQKAAETKLLEIKERKERRRRSLRAAALSAPIEAGEEDAFEDDGEEEREAWLATISLALCKAFDLLDMLKKEEEMLLAVKERQAKDGNAFAREMLDERTKKAEAWHHNAANRAPYSKPADPITCATFAQDVIEGRASVSQAHEHKHQPLIFGPASLVGGGLTSERERMAAQVFQPSYRLPTMSIEEAGLREMKMMEKWQERTAKMIQESNSAWHKDGSRSAQEDEDAEEEKARAWDDWKDDNPRGAGNKKLTPCG
What is the function of this protein?
Involved in the regulation of the TOR signaling pathway.  Seems to act as a regulator of PP2A catalytic activity.
What are the official names of this protein?
PP2A regulatory subunit TAP46.
What is the protein family that this protein belongs to?
Belongs to the IGBP1/TAP42 family.
Protein: RS6_LEGPA
Sequence: MRHYEIMFLVHPDQSEQVPGMVERYEGIITKHNGKIHRKEDLGRRQLAYSINKVHKAHYILMNVECNLDALNEIKNAFKFNDAILRHLITVQKQAITTESVLMKKEKETKVA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GUAC_STRP7
Sequence: MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVVPANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEYDFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRILLPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: PTOV1_MOUSE
Sequence: MVRPRRAPHRSGAGGPLGGRGRPPRPLVVRAVRSRSWPGGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRRLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG
What is the function of this protein?
May activate transcription.  Required for nuclear translocation of FLOT1.  Promotes cell proliferation.
What are the official names of this protein?
Prostate tumor-overexpressed gene 1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Cytoplasm, perinuclear region. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts.
Protein: BEV1L_BETPN
Sequence: MGVFNYETEATSVIPAARMFKAFILDGDKLVPKVAPQAISSVENIEGNGGPGTIKKINFPEGFPFKYVKDRVDEVDHTNFKYNYSVIEGGPVGDTLEKISNEIKIVATPDGGCVLKISNKYHTKGNHEVKAEQVKASKEMGETLLRAVESYLLAHSDAYN
What is the function of this protein?
May be a general steroid carrier protein.
What are the official names of this protein?
Major pollen allergen Bet v 1-L, Allergen Bet v I-L.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y386_MYCPN
Sequence: MKTPLKPKFQPAKIANAVVVGGMIAFGKTTIAESLAKHLKGSKVIYELEEQDQLADLLLAKMYERNDELLYAPLFQLYFTLNRFNKYRKECNNKTPTIFDRSIFEDWLFAKQNIHRPSIFTYYNHLWNGIVKELIFKHGIPALYVILEGDWELFEQRLFQRNRKVEIDNFAKNKDYFKNLYKIYGEFIKNVCYDFGISHCIVNANQSVESITKQVLEVLKSKNLDWEII
What are the official names of this protein?
Uncharacterized protein MG268 homolog.
Protein: NUOD_BURVG
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIERLLGIDVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQFKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGLTGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCIEWLRKNQGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TOX1_BORPE
Sequence: MRCTRAIRQTARTGWLTWLAILAVTAPVTSPAWADDPPATVYRYDSRPPEDVFQNGFTAWGNNDNVLDHLTGRSCQVGSSNSAFVSTSSSRRYTEVYLEHRMQEAVEAERAGRGTGHFIGYIYEVRADNNFYGAASSYFEYVDTYGDNAGRILAGALATYQSEYLAHRRIPPENIRRVTRVYHNGITGETTTTEYSNARYVSQQTRANPNPYTSRRSVASIVGTLVRMAPVIGACMARQAESSEAMAAWSERAGEAMVLVYYESIAYSF
What is the function of this protein?
S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B. pertussis causing disruption of normal host cellular regulation.  It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins.  In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide.  It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
What are the official names of this protein?
Pertussis toxin subunit 1, PTX S1, Islet-activating protein S1, IAP S1, NAD-dependent ADP-ribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial exotoxin subunit A family.
What are the subcellular locations of this protein?
Secreted. Note=The individual chains are secreted by a sec-dependent mechanism into the periplasm. Then, S1 associates with the outer membrane before it joins with the B subunit to form the secretion-competent holotoxin. The type IV secretion system ptl mediates secretion of assembled toxin through the outer membrane.