PharMolix/UniProtQA huggingface dataset:
Protein: PSBA2_GLOVI
Sequence: MATILRRRSLGNPWEQFANWITSTDNRFYIGWFGVLMVPTLLSATICFVVAFIAAPPVDMDGIREPISGSLLYGNNIITGAVIPSSNAIGLHFYPIWEAASMDEWLYNGGPYQLVVFHFLIGIFAYLGREWEFSYRLGLRPWICVAYSAPVAAATAVFLIYPMGQGSFSDGMSLGISGTFNFMFIFQAEHNILNHPLHMFGVAGVFGGSLFAAMHGSLVTSSLIKATSYEESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFTNSRSLHFFLAAWPVIGIWLTSLGICVMGFNLNGFNFNASITDNQGRTIYTWADIVNRANLGIEVMHERNAHNFPLDLAGTESAPVAFAAALGDG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 2, PSII D1 protein 2, Photosystem II Q(B) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_ECO81
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_PROMA
Sequence: MSERKQILNCIDDPQQALIMLKRISARTSLEVQENAISSVQNILTEVKQLGDEALFRLTEKFDGFIPKPLEITPEQTLEAWEKTPTPLQEALQLAKNRIEAFHKYQIPKDFLKEGIHGELLGKNWSPVEKAGIYIPGGRAAYPSTVLMNAVPALVAGVNEIIMVSPAGPNGQLNRTVLAAAYIAGIKKIFRIGGAQAIGALSYGTQTIPRVDVISGPGNLYVTLAKKLVYGQVGIDSLAGPSEVLIIADHSADVEQVATDLLAQAEHDPLAASILLTTESNLAKKINLEIENQLKDHPRSAICRKSLKDWGLIVICKDIKSCAALSNSFAPEHLELLIEKPFEFISQIKNAGAIFLGEWSPEATGDYLAGPNHTLPTSGTARFSSALSVETFMKSTSIINFNQAALNKTSAAIMELANSEGLHSHSRSIEIRRSKPSSDD
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: Y1211_METTH
Sequence: MIERLRGALASASFPVMALLLLSAIVVYPLWTMLFLGAVFAYIVRPVALRINRRIPYLSVSIILAMIVVIMPLVGILVFTVDSIINSAPSLLSLAGSIHVPGAGNLQPSAENTLANLRTVLRDILSGSLNYVVAILQSVPMISLQLFVFLSSTFYFARDGKRLVGYIRTLIPEETRPFMERMASETERVLLSIFYGHFLTALAIGLMAAVGFHLLGYPYAILLGIMTGLFQLIPVIGPWAAYTPLSIYDFVTGNILRGVLVLIFGLFLSTIDIYLRPKLSGKYADIHPMIFLVGFLGGPVVWGVAGFIVGPLVLGLAYAALEAYRMESGGEEVQ
What are the official names of this protein?
Putative transport protein MTH_1211.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H8A11_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVACYASESEKKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 11, U3-TRTX-Hhn1a, Hainantoxin-VIII.11, HNTX-VIII.11, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IBBB6_HYAOR
Sequence: GRRPCCNECGICDRSLDPMCICEDLVPQCHEGCQACEKVDTGTPMYQCRSFEYYHCGPICY
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Inhibits trypsin (Ki = 30 nM) and weakly inhibits chymotrypsin (Ki = 550 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor B6, HOSPI-B6.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: K0232_HUMAN
Sequence: MYPICTVVVDGLPSESSSSSYPGPVSVSEMSLLHALGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQEQENDIFLGWEKGAYKKWGKSKKKCSDLTLEEMKKQAAVQCLRSASDESSGIETLVEELCSRLKDLQSKQEEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEKPVCLQEIMTVWNKSKVCSYSSSSSSSTAPPASTDTSSPKDCNSESEVTKERSSEVPTTVHEKTQSKSKNEKENKFSNGTIEEKPALYKKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKAREIRNKKGRNGQSRLSLKHGEKAERNIHTGSSSSSSSGSVKQLCKRGKRPLKEIGRKDPGSTEGKDLYMENRKDTEYKEEPLWYTEPIAEYFVPLSRKSKLETTYRNRQDTSDLTSEAVEELSESVHGLCISNNNLHKTYLAAGTFIDGHFVEMPAVINEDIDLTGTSLCSLPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQGESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDSTSSVGAEGLFLQDLGNLAQFWECCSSSSGDADGESFGGDSPVRLSPILDSTVLNSHLLAGNQELFSDINEGSGINSCFSVFEVQCSNSVLPFSFETLNLGNENTDSSANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEETRSDNETLNIQFEESTQFNAEDINYVVPRVSSNYVDEELLDFLQDETCQQNSRTLGEIPTLVFKKTSKLESVCGIQLEQKTENKNFETTQVCNESPHGDGYSSGVIKDIWTKMADTNSVATVEIERTDAELFSADVNNYCCCLDAEAELETLQEPDKAVRRSEYHLWEGQKESLEKRAFASSELSNVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPSHTKGSLLQCAASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDQPKSGENGLNKGFSFIFHEDLLGACGNFQVEDPGLEYSFSSFDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPGGGSESEFESEKDEANIPIPSQVDIFEDPQADLKPLEEDAEKEGHYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEESTGILSVGKQNQCLECSMNESLEIDLESSEANCKIMAQCEEEINNFCGCKAGCQFPAYEDNPVSSGQLEEFPVLNTDIQGMNRSQEKQTWWEKALYSPLFPASECEECYTNAKGESGLEEYPDAKETPSNEERLLDFNRVSSVYEARCTGERDSGAKSDGFRGKMCSSASSTSEETGSEGGGEWVGPSEEELFSRTHL
What are the official names of this protein?
Uncharacterized protein KIAA0232.
Protein: GDL45_ARATH
Sequence: MNITKLTPWFLFSCLILLSDYIKVNSSISPSSEQTQEDGFFGFKPTKLFVFGDSYADTGNTPFLIVPSWRFPNGITFPGIPTGRFSDGRVSTDYLAKYIGVRTPITYKWGKYGRPRLAVKRGMNFAYGGAGAFETMFKLVPTASVQIDSFEQLLMRNVYSPADLNSSVAFFSIIGNDYLTYDRRNGSEEGRSALTRKVVKQILLDVKRIKDLGVRKVLVALSPPQKCLPKLVTPKGCDTNDTSTYLHNSLLRKGLIKLNDKEINNNDKSFMTLDLYNAFVTIFKNKGVSGVSTFPDPFKACCATKRGTFCGDRSLSGKKLYTLCDDPKSFFFWDNVHISDQGWRSVFSLLLPDSQF
What are the official names of this protein?
GDSL esterase/lipase At2g36325, Extracellular lipase At2g36325.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRR2_CANAL
Sequence: MTKRDRTIYSCDACRSRKIKCNRQTPCASCHKSKRDCVYTVSRQRDAQITNRKLDKKTYHQISAIEKKISALEGKKGLLQVETINFNKSFTDQTPLVELQSLFPYLLLSKQDPGCVLVRHHCHHLLEKDPRYFEYSQLLADLSLTKRHHLTARAKALLGEAYIPSPQEGHTIDQLKHVLSLNPNFRFAGNFADPLTSFFSLIPPAWANKQLVDTFFQHIYPVIPIIDETDFNTSINRVLGPQIDGHYINSFPSIGSADDLPFLALFLLVLRISYMYTPGACPVSYDTLRAAETIMKEFDITKTHSLTALQAEIMLRFYKIVAPESYTQSNYVQVSVGVLIQNCYSLALHRDPEYIGEHNPKQQHLRRKIWHLLLRMEVIDSAIFQTILSSNPDASDTKLPQLIDQAPPMEQSIVKHIWRSTDLFVSLRKLVEINSKTSEDTPLETVLELLVEVETKLQAFLATIDSEASTVFYNDLVIFSVNFLLVYMYYSLYLFKGPTPLGNKYLLKSAQILFVDLARTRSTSLFLAYFNLNYIHLVLMITNFLRMRVDCIIHRHLRAQDSSVQDLQCCRYFLKIIFFSHVKELGNYSSSHKYAWQMRKVYLTLAKIMERSSDVLISNDPELVKSAAVDIPVKEINKLLEQYINFKGFTPTTLFDPTDNELIDEMQHENLWNAMENIEYSEKVYSGWIDAIKNVPSNWDWDYWDFLKIS
What is the function of this protein?
Transcription factor that controls the expression of CDR1, the major multidrug efflux pump.  Required for yeast cell adherence to silicone substrate and plays a role in virulence.
What are the official names of this protein?
multidrug resistance regulator 2.
What are the subcellular locations of this protein?
Nucleus. Membrane; Multi-pass membrane protein.
Protein: NU4LM_NYCSU
Sequence: MTLVMFNITIAFTLSLLGTLMFRTHLMSTLLCLEGMMLCLFIMAVITSLDTHPMIMYPIPIIILVFAACEAAVGLALLAMVSSTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSB_STRPQ
Sequence: MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGEREADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQMLESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: CAD_DROME
Sequence: MVSHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAVGTLSM
What is the function of this protein?
Caudal (cad) is one of a number of transcription factors controlling segmentation of the embryo.  Further transcriptional regulation via a 5' flanking region containing DNA replication-related elements (DRE) and by dref also regulated by trh and tgo via the CNS midline element.  Alongside Bicoid (bcd), caudal forms concentration gradients down the anterior-posterior (A-P) axis providing positional information and subsequent induction of the gap genes.  Plays a role in gastrulation/germ band extension, hindgut morphogenesis, positive regulation of cell proliferation, genital disk development and pattern formation.  Acts as a key regulator of the Hox gene network and activates transcription via the downstream core promoter element (DPE) relative to the TATA box.  Plays a role in the establishment of the hindgut and in the invagination of the hindgut primordium during gastrulation.  These effects on the gut are achieved by acting combinatorially at the posterior of the embryo to activate transcription of different targets including fog, fkh and wg.  Caudal is involved in regulation of proliferation through transactivation of the E2F gene.  Postembryonically its function is mostly restricted to the intestine where it regulates antimicrobial peptide (AMP) levels preserving the normal gut flora.
What are the official names of this protein?
Homeotic protein caudal.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RMUC_XYLFA
Sequence: MQPDFLILGCLLCIVLVLQILALLRRSDHTALDHVLREEHRVGRAELREQLETLERQQEVRLASFARSLTDLVARIDQRLDQLTASLGEDARKGRQEASEGQQRFADALGQRLTELTQRNAQSINEMRTTLEQQLHVLRADNAQQLEQIRAIVDEKLQTTLNTRLDSSFKLVSERLEQVQRGLGEMQQLATGVGDLKRVLTHVKSRGTWGEVQLDNILDQTLTQEQYARGVRVCPDASEIVDFAVRLPGRGQYEAPVWLPIDVKCPKEDYERLLDAQEQADQELVRTMGVQLERAIKIQAKSIRDKYIVPPHTTDFAVMFLPTEGLYAETIRRPGLADVLQREYRVVVAGPTTVTALLNSLQMGFRTLAIEQRSSEVWSLLGAVKSEFGKFAGILEKAEKQINTVGKSLGEAGRKTRTIERRLRGVESLSQEQTQVLLDGLDVDAAESDVDSDASF
What is the function of this protein?
Involved in DNA recombination.
What are the official names of this protein?
DNA recombination protein RmuC homolog.
What is the protein family that this protein belongs to?
Belongs to the RmuC family.
Protein: Y2213_MYCBO
Sequence: MRLDQRWLIARVIMRSAIGFFASFTVSSGVLAANVLADPADDALAKLNELSRQAEQTTEALHSAQLDLNEKLAAQRAADQKLADNRTALDAARARLATFQTAVNKVAAATYMGGRTHGMDAILTAESPQLLIDRLSVQRVMAHQMSTQMARFKAAGEQAVKAEQAAAKSAADARSAAEQAAAVRANLQHKQSQLQVQIAVVKSQYVALTPEERTALADPGPVPAVAAIAPGAPPAALPPGAPPGDGPAPGVAPPPGGMPGLPFVQPDGAGGDRTAVVQAALTQVGAPYAWGGAAPGGFDCSGLVMWAFQQAGIALPHSSQALAHGGQPVALSDLQPGDVLTFYSDASHAGIYIGDGLMVHSSTYGVPVRVVPMDSSGPIYDARRY
What are the official names of this protein?
Probable endopeptidase Mb2213c.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: UBP20_XENTR
Sequence: MGDAEDFCPHLDSIGEVTKEDLILKSKGTCESCGVGGPNLWACLQDGCQSVGCGESYVDHSTLHAQAKKHNLTVNLTTFRVWCYACEKEVFLDPRGPPASQTTSPRLSHRDFPTSAHPLKSVPIAVGDDGESESDEDDIKPRGLTGMKNIGNSCYMNAALQALSNCPPLTQFFLECGGLVRTDKKPALCKSYQKLISELWHKKRPSYVVPSSLYHGIKLINPLFRGYSQQDTQEFLRCLMDQLHEELKEPVPLETQEREEEDRDDQREGERGGTVEEDFLSCDSGGEMGDGEGGGGVGTLSEMELLIREEVGRGLSEKEKLKERKLSYCHRRTSSEQADEDADVDTAMIPEPDNDAYVHCSSRSCSPHPVESISKHSSTPPRSSPLRTSHSYVLKKAQVLSGGKKRSEVRYRSVISDIFDGSILSLVQCLTCDRVSTTIETFQDLSLPIPGKEDLAKLHSTIHQSAVSKAGTCGDSYAAQGWLSFFMDYIRRFVVSCIPSWFWGPMITLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKIGSHVSFPLEGLNLRPFLAKECVSRITTYDLLAVICHHGSASSGHYISYCQNVINGQWYEFDDQYVTEVHETVVQNAEAYVLFYRKSSEEAERERQKVVSLAAMKESGLLQFYISREWLNKFNTFAEPGPISNQSFLCSHGGIPPNKYHYIDDLVVILPQSVWEYLYNRFGGGPAVNHLYVCSICQVEIEALAKRRKTEIDTFIKLNKAFQAEEAPSVIYCISMQWFREWEAFVKAKDSDPPGPIDNSKVALTKSSGQVQLKQGADYGQISEETWNYLLNVYGGGPEIAIRQTVAQYQEAEHLHGEQKIEAETRAG
What is the function of this protein?
Deubiquitinating enzyme involved in beta-2 adrenergic receptor (adrb2) recycling.  Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (adrb2).  Plays a central role in adrb2 recycling and resensitization after prolonged agonist stimulation by constitutively binding adrb2, mediating deubiquitination of adrb2 and inhibiting lysosomal trafficking of adrb2.  Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 20, Deubiquitinating enzyme 20, Ubiquitin thioesterase 20, Ubiquitin-specific-processing protease 20.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP20/USP33 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: MOAC_SHESH
Sequence: MSNEFTHINADGNAHMVDVTEKAVTEREARAEAYIEMAADTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVELEAQPEFNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQTRLLEKRGGKSGHFKV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: WRIP1_RAT
Sequence: MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGPHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGLGKRPAAAAAAGSASPRSWDETEAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALPAEEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLETNEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNTALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKMFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQDYLPEELRGVDFFKQRRC
What is the function of this protein?
Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis.  In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased.  Also plays a role in the innate immune defense against viruses.  Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination.  In turn, RIGI transmits the signal through mitochondrial MAVS.
What are the official names of this protein?
ATPase WRNIP1, Werner helicase-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with WRN in granular structures in the nucleus.
Protein: KITH_CHLSY
Sequence: MTRPSDGGRIEVICGCMYSGKTEELIRRMRQVRIARQSYRIFTPRMDTRYAEGQVASHSGSRLEAITVATMKDILAHAEDAQVVAIDELHLFDDDPAEMVRGCQWLANRGVRVIVAGLDLNYRAEPFPAMMHLLALAEQVDKLYAICVKCGAYATRSQRLIDGKPAPADAPTIVVGGLDMYEARCRTCYEPAV
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACR2_ARATH
Sequence: MQKVCWPYFDPDFDNLGERIYGPPCRVYIDNDSIQDCTVVKVNSENKQGLLLEVVQILTDMNLIITKSYISSDGGWFMDVFHVKDEHGNKLTDKSVINHIKHAIGTSRRESDFIKASEANNNSLEPQLADHGEHTAIEMTGTDRPGLFSEIFAAFADLHCNVMEAHAWSHNARLACIAYVSDDNTHTPIDDPSRLASIEDHLSTVIRATADPASNSTHVGHKENETDGFLAGQGKGCMNSNMERRLHQLMLSVRDFDEPFCEPSSLSLLSSKLEYCDHKERKTTIVSIGNCEERGYSIVTVKSKDRRRLMFDTICTLVDMQYVIFHAALRSDGADAFQEYFIRHIDGRALNTEGEKERVIKCLEAAIERRVCEGVKLELCAENRVGLLSDITRVLRENGLTVVRADVETQGQKSLNAFYVRDISGNKIDMEFVESVKKEMRPIHLEVKNEDTKIDTVGSDEPTASASATPQRQPQPHRFSLGDILRSQMERLSLNFVPTK
What is the function of this protein?
May bind amino acids.
What are the official names of this protein?
ACT domain-containing protein ACR2, Protein ACT DOMAIN REPEATS 2.
Protein: CITRX_SOLTU
Sequence: MQAASLAFHPPALHTSPSYFSSKLPHHLNYSLFSHTPPTSTLSLTQTLSRKSICQPRAVGKYVREDYLVKKLSAKEIQELIKGERNVPLIIDFYATWCGPCILMAQELEMLAVEYENNALIVKVDTDDEYEFARDMQVRGLPTLYFISPDSSKDAIRTEGLIPIQMMRDIINNDL
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may play a role in proper chloroplast development.
What are the official names of this protein?
Thioredoxin-like protein CITRX, chloroplastic, Cf-9-interacting thioredoxin, StCiTrx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant CITRX-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GSTFE_ARATH
Sequence: MADSKMKLHCGFIWGNSAALFCINEKGLDFELVFVDWLAGEAKTKTFLSTLNPFGEVPVLEDGDLKLFEPKAITRYLAEQYKDVGTNLLPDDPKKRAIMSMWMEVDSNQFLPIASTLIKELIINPYQGLATDDTAVQENKEKLSEVLNIYETRLGESPYLAGESFSLADLHHLAPIDYLLNTDEEELKNLIYSRPNVAAWVEKMKMRPAWLKTVVMKNHIVDLMKQRRLPIKLDSSCHESTVVAQKNAIAIENK
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase F14, AtGSTF14, GST class-phi member 14.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CLPX_STAA9
Sequence: MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YQGF_SALTI
Sequence: MSDTLLAFDFGTKSIGVAIGQRITGTARPLPAIKAQDGTPDWTLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVTVTLHDERLSTVEARSGLFERGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFDP1_MUNRE
Sequence: MEEFDSEDFSTSEEDEDYVPSGGEYSEDDINELVKEDEVDGEEETQKTKGTKRKAESVLARKRKQGGLSLEEEGEEDANEESGGSSSEEEDAATGQEKGIESEDARKKKEDELWASFLNDVGPKSKVPPSTHVKTGEETEETSSSHLVKAEKLEKPQETEKVKITKVFDFAGEEVRVIKEVDATSKEAKSFFKQNEKEKPQSNISSSVPSLSAGSGLKRSSGMSSLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSQMKP
What is the function of this protein?
May play a role during embryogenesis.
What are the official names of this protein?
Craniofacial development protein 1, Bucentaur.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: YR814_MIMIV
Sequence: MRQFKRAYAKSLADNSNDTNSNGVTPLQYAIKTHNDYKIRKILKKYKTWKNIMEDLQYPLDIPEFDDPTKYFTEIASNSETETFKMILELDPEITDDNIKHFMINCRGNNCMEKFDMLHKHPSVKDKIGLFNSRNNVGSYIIFHARFDIDKIKNFEKRFGKIKIDNEMINVLTGPGYYWGGGSCQKNFEIIQDLENNFEVDYSRLNIGECECSNVLDFIINRRDISEIIDQDNSRNPTDRIIFKKKYDLLWEEKHRYTGSKKRIKEREKCIDILLDKGFADAKTSSVIRYYNNLHNGYQYGPYMD
What are the official names of this protein?
Uncharacterized protein R814.
Protein: CRADD_HUMAN
Sequence: MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGLRAVEVDPSLLLHMLE
What is the function of this protein?
Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis (PubMed:9044836, PubMed:15073321, PubMed:16652156, PubMed:17159900, PubMed:17289572).  Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway (PubMed:8985253).
What are the official names of this protein?
Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain.
Protein: RNPH_PHOLL
Sequence: MRPTGRAAEQVRPITITRHYTKHAEGSVLVEFGDTKVLCNASVEEGVPRFLKGQGQGWVTAEYGMLPRSTHTRNAREAARGKQGGRTMEIQRLIARSLRAAVDLKKLGEYTITLDCDVIQADGGTRTASITGACVALVDALNKIVEAGKLKESPLKSMVAAVSVGIVDGEGRCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHDELLSLLALAKGGLEDIFDAQRNALKQNALK
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PYRB_COREF
Sequence: MKHLLSIADLSRDEIISLLDEADRFKEVLEGREVKKLPTLRGRTIFTLFYENSTRTRSSFETAGKWMSADVINISASSSSVKKGESLKDTGLTLSAIGADAIIMRHPSSGAAQQLAGYVAPGGVGPSVINAGDGSHQHPTQALLDALTLRQRLGGIEGRKIVIVGDILHSRVVRSNVDLLSTLGAEVILVAPPTLLPYGVENWPVRTSYDMDAEIRDADAVMMLRVQQERMQGGFFPSHREYATLYGMSKAREASLKDSAIIMHPGPMLRGMEINFGVADAPRTAVLQQVSNGVHVRMAVLFALVAGSDATI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.