PharMolix/UniProtQA huggingface dataset:
Protein: DNAG_PYRCJ
Sequence: MGALTIVAKYMIVAQIEVNGGVDKSDIIGALFSQTEGLLGKDMDLRELQMMGRIGRIEVDIQEKDGKTKAKIYIPSNLDRYETALVAALIESIERVGPYPATVKVLEIRDLREEKRKKIVERAKELIKMIEEEILPDTKEIIEKLKEDVAKAEVVEYGPEKLPAGPDVDKSDWIIVVEGRADVVNLVKHGYRNVIALEGISRGVPQTIIDLSKRKSITLFIDGDKGGEMVLKELMKVAHIDYVARAPPGKEVEQLTAKEIAKALRNKVTLEEWLAQQKAGAEKTEAAAPPPQQPTAPPAAPSQQPIAEVPQEIVKRLGDMQGTLEAELYDTNWSLIKRIAVRELPDELANSTDSIYAILMDGIVTQRIVDLAAKKGVKIIITARVGPLTKVPEDLKIVTFEQLQKLA
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: VOPP1_BOVIN
Sequence: MDSLAWRVAALLLGLLVECTEAKKHCWYFEGLYPTYYICRPYEDCCGSRCCVRALSIQRLWYFWFLLMMGVLFCCGAGFFIRRRMYPPPLIEEPAFNVSYTRQPQNPTPGAQPLGLPYYTDPGGSGMNPAGNPVAMAFQVQPNSSQGSTAYPPPPSYCNTPPPPYEQVVKTK
What is the function of this protein?
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
What are the official names of this protein?
Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, ECop.
What is the protein family that this protein belongs to?
Belongs to the VOPP1/ECOP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
Protein: NU2C2_PELHO
Sequence: MLDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNHFNEIFQFLILLCSTLSIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDFITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHAFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLSFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPHVRNYKRSPLRSKNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RFCL_AERPE
Sequence: MPIVARSSRVPWVIKYRPKRVEDVVNQDQAKKILVPWFKAWLEGRKPDKRAALLYGPPGVGKTSLVEAIASEFNLEMIELNASDYRRRSDIERIVGAASRKRSMFKRGVVILLDEVDGINPREDAGGIEALLSVIKTTENPIVMTANDPWKDFLRPLREVSLMVEFRPLTLTHIVAVLQRICEAERIECEREALRYIAERSEGDLRSAINDLQAVAEGYGRVTLTLAREIVRGREKSIDIWRTLNQVFYKPRQAWMARKAVSQSEKDYEELIAWINDNIPRKYGEPSDLFRAFDALARATVFLGRAKFGGNWELLSYVFDLMGPGVAYARMEGEVLKTRYSYPEKIRMMAQLRGVRETREKLAEVLAKRLLMSRRAVKTEVLPILHYIFRSSRDPTKPAMIALEYGLTEKMVELLAGQRKSEILKAMATVKKARLGEKPLEPQEAKARRRGEKASRDEGRKAGKRERKGVGLDFFLGEQ
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: CH60_TANFO
Sequence: MAKEIKFDMNARDLLKKGVDELANAVKVTLGPKGRNVILEKKFGAPQITKDGVTVAKEIELACPYENMGAQLVKEVASKTNDKAGDGTTTATVLAQAIIGVGLKNVTAGANPMDLKRGIDKAVSKVVESIASQSEAVGTNMDRIEHVAKISANGDEGIGKLIAEAMQKVKKEGVITVEEAKGTETTVEVVEGMQFDRGYISAYFVTDTEKMETQFENPYILIYDKKISVLKDLLPILEQMVQSGRALLIIAEDIDSEALATLVVNRLRGGLKVCAVKAPGFGDRRKAMLEDIAILTGGTVITEEKGMKLEDAKMDMLGSADKVTVNKDNTTIVKGNGDKAAIESRIGQIKAQIETTTSDYDKEKLQERLAKLAGGVAVLYVGAPSEVEMKEKKDRVDDALHATRAAIEEGTVPGGGVAYLRAIPALEGLKGENEDETTGIEIVKRAIEEPLRQIVNNAGKEGAVVVQKVKEGTGAFGYNARTDVYEDLSEAGVVDPAKVTRIALENAASIAGMFLTTECVVADKKEEAPAPPMNPGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_ECOK1
Sequence: MMEKHYVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSVERAGEEHDIFANTLRQQGIEVLLLTDLLTQTLDIPEAKSWLLETQISDYRLGPTFATDVRTWLAEMSHRDLARHLSGGLTYSEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTSCWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFAGGEFIKYFGDENINYDHATLEGGDVLVIGRGAVLIGMSERTTPQGIEFLAQALFKHRQAERVIAVELPKHRSCMHLDTVMTHIDIDTFSVYPEVVRPDVNCWTLTPDGHGGLKRTQESTLLHAIEKALGIDQVRLITTGGDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRGGARCMSCPLHRDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTDA_METHJ
Sequence: MTPKEQSPTTLLISSRKDPAGSLIHEELYSFLEDDKRAHSHIRHWHAEERLIYLDGPSLPHDADRILFLSRHASERPRPVLTVHVTGNFGSADYGGRPNTLTPAATGLMHALINRLIIHAPEGYEVMYEATHHGPTDIPLPSCFIELGSTEKEWNDRIAARAVAQAVLDALLMDTSSVIPLAGFGGTHYAQRQTEITKLTRGGFGHIMPTRDIPHLTDALFQDIISSTGAFAIYIDGKSMSGKEERMITGLADKHTIPILGQGDLMRLFDLPFSEYMSIRNLAESLIPGSSIVLHTILEMPAPVSLTIPGELVDEVMKVAAEEFISALDSFPIVHMTGRGKACHPVFITDAAFSGRISDELIHLCVTLLQDRYTCSFEGDSLIIKKLRFDPKKAKNLGIPSGPLYSELMAGKPVEVGDSVIYPEMVMTETEKRIHIPQRQAR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: 6PGD_SCHPO
Sequence: MSQKEVADFGLIGLAVMGQNLILNGADKGFTVCCYNRTTSRVDEFLANEAKGKSIVGAHSLEEFVSKLKKPRVCILLVKAGKPVDYLIEGLAPLLEKGDIIVDGGNSHYPDTTRRCEELAKKGILFVGSGVSGGEEGARYGPSLMPGGNPAAWPRIKPIFQTLAAKAGNNEPCCDWVGEQGAGHYVKMVHNGIEYGDMQLICETYDIMKRGLGMSCDEIADVFEKWNTGKLDSFLIEITRDVLRYKADDGKPLVEKILDAAGQKGTGKWTAQNALEMGTPVSLITEAVFARCLSSLKSERVRASKKLTGPNTKFTGDKKQLIDDLEDALYASKIISYAQGFMLMREAAKEYGWKLNNAGIALMWRGGCIIRSVFLKDITEAFREDPNLESILFHPFFTNGVEKAQAGWRRVVAQAAMLGIPVPATSTGLSFYDGYRSAVLPANLLQAQRDYFGAHTFRVLPEAADKSLPADKDIHINWTGHGGNISATTYDA
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: LKA2E_MANHA
Sequence: MGNKLTNISTNLKSSWLTAKSGLNRTGQSLAKAGQSLKTGAKKIILYIPKDYQYDTDKGNGLQDLVKAAEELGIEVQKEESNDIAKAQTSLGTIHNVLGLTERGIVLSAPQLDKLLQKTKVGQAIGSTENITKGFSNAKTVLSGIQSILGSVLAGMDLDEALQNNSNELTLAKAGLELTNSLIENIANSVKTLDAFGDQINQLGSKLQNVKGLSSLGEKLKGLSGFDKTSLGLDIVSGLLSGATAALVLADKNASTSRKVGAGFELANQVVGNITKAVSSYILAQRVAAGLSSTGPVAALIASTVSLAISPLSFAGIADKFNHAKSLESYAERFKKLGYDGDNLLAEYQRGTGTIDASVTAINTALAAIAGGVSAAAAGSVVASPIALLVSGITGVISTILQYSKQAMFEHVANKIHNKIVEWEKNNPGKNYFENGYDARYLANLQDNMKFLLNLNKELQAERVIAITQQQWDNNIGDLAGISRLGEKVLSGKAYVDAFEEGQHLKADKLVQLDSAKGIIDVSNTGEAKTQHILFRTPLLTPGTEKRERVQTGKYEYITKLHINRVDSWKITDGAASSTFDLTNVVQRIGIELDNAGNVTKTKETKIIAKLGEGDDNVFVGSGTTEIDGGEGYDRVHYSRGNYGALTIDATKETEQGSYTVNRFVESGKALHEVTSTHTALVGNREEKIEYRHSNNQHHAGYYTKDTLKAVEEIIGTSHNDIFKGSKFNDAFNGGDGVDTIDGNDGNDRLFGGKGDDIIDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRQGDGNDSITESEGNDKLSFSDSNLKDLTFEKVNHHLVITNTKQEKVTIQNWFREAEFAKTIQNYVATRDDKIEEIIGQNGERITSKQVDELIEKGNGKIAQSELTKVVDNYQLLKYSRDASNSLDKLISSASAFTSSNDSRNVLASPTSMLDPSLSSIQFARAA
What is the function of this protein?
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture.  The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell (By similarity).  This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis.  It has also weak hemolytic activity.
What are the official names of this protein?
Leukotoxin, Lkt.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: PKP3_HUMAN
Sequence: MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQPRHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWSSRSAVDLSCSRRLSSAHNGGSAFGAAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFAYERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFLGP
What is the function of this protein?
May play a role in junctional plaques.
What are the official names of this protein?
Plakophilin-3.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Nucleus. Cell junction, desmosome. Note=Nuclear and associated with desmosomes.
Protein: KTHY_EHRRW
Sequence: MFITFEGIDGSGKTTQSRLLTEYLSGVYGVDNVILTREPGGTFFNESVRNLLFSTKNLDKLSELLFFIAMRREHFMKVIKPALTQQKIVICDRFIDSTIAYQGYGHGIDCKLIEELNDLVVDIYPNITFVLDSDINQSVARSNKNGYEFLDLEFYARVRDGFRDIVKRNQYRCYLITNVDATKNINEISAIYLKTIKILHAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DAPAT_SYNE7
Sequence: MATINDNYLKLKAGYLFPEIARRVNAFAQSNPEAAIIRLGIGDVTEPLPVACRQAMIQAVEDMGQRENFKGYGPEQGYAWLREKIAAHDFQSRGCEVDASEIFISDGSKCDCGNILDIFGNNNRIAVTDPVYPVYVDTNVMAGHTGDANDRGEYDGLVYLPISAENNFTAEIPSEKVDLIYLCFPNNPTGAVASREYLQAWVDYARANGAIILFDAAYEAFITDPAIPHSIFEIPGARDCAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKAADGSEVELWGLWNRRQSTKFNGVSYIVQRGAEAVYSAEGQAQIKELVAFYLENARIIREELTAAGLDVHGGVNAPYVWVKTPAGLTSWDFFDKLLQVCNVVGTPGSGFGAAGEGYFRISAFNSRENVVTAMQRIRSAGLA
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: XERDL_STRPD
Sequence: MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLLYQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINTDIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLSFQMLTLKTKKGVRVLPLSQILIPFLEQQLIGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFILKEKLAGKSIIELSDILGLKSPVTLEKYYKS
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN2_ARATH
Sequence: MGVPSFYRWLIQRYPLTIQEVIEEEPLEVNGGGVTIPIDSSKPNPNGYEYDNLYLDMNGIIHPCFHPEDKPSPTTFTEVFQCMFDYIDRLFVMVRPRKLLFMAIDGVAPRAKMNQQRARRFRAAKDAAEAAAEEEQLREEFEREGKKLPPKVDSQVFDSNVITPGTEFMATLSFALRYYIHVRLNSDPGWKNIKVILSDANVPGEGEHKIMSYIRCNKNHPGYNPNTHHCLYGLDADLIMLSLATHEIHFSILREVVFFPGEEGKCFLCGQEGHRAADCEGKIKRKTGEMLDNTEADVVVKKPYEFVNIWILREYLEHDMQIPGAKKNLDRLIDDFIFICFFVGNDFLPHMPTLEIREGAIELLMSVYKNKFRSAKKYLTDSSKLNLRNVERFIKAVGMYENQIFQKRAQVQQRQSERFRRDKARDKARDNARDNAQASRQFSGKLVQLDSLDEVSDSLHSSPSRKYLRLSLDDNIGVANVETENSLKAEELDNEEDLKFKLKKLLRDKGDGFRSGNGEQDKVKLNKVGWRERYYEEKFAAKSVEEMEQIRRDVVLKYTEGLCWIMHYYYHGVCSWNWFYPYHYAPFASDLKGLEKLDIKFELGSPFKPFNQLLAVLPSASAHALPECYRSLMTNPDSPIADFYPADFEIDMNGKRYSWQGISKLPFVEEKRLLEAAAQVEKSLTNEEIRRNSALFDMLFVVASHPLGELIRSLNSRTNNLSNEERATIIEKIDPGLSDGMNGYIASCGGDSQPSCFCSTVEGMEDVLTNQVICAIYKLPEDIRGSEITHQIPRLAIPKKTISLVDLKSGGLLWHEDGDKRRAPPKVIKIKRYNPEGSISGGRLGKASHRLVLQTINAQPDYMNINSEPALCPNTVFQNERVPKKIPTFKDNGIQWISPPPSQITPKKMNSPQRQKAWKKDETPQSREKSKKLKSSLKVNPLKMKKTKSPQREFTREKKKENITPQRKLTKAQRQVKHIRMMEEAKMIKQRKKEKYLRKKAKYAQGAPPKTA
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity (PubMed:11106401).  Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor.  Degrades miRNA-derived loops, excised during miRNA maturation in the nucleus (PubMed:17993620).  Involved in pre-rRNA processing.  Involved in the primary exonucleolytic shortening of the 5' external transcribed spacer (5'ETS), required for endonucleolytic processing at site P by the U3 snoRNP complex.  Involved with XRN3 in the 5'-end processing of 5. 8S and 25S rRNAs.  Contributes with XRN3 to polyadenylation-dependent nuclear RNA surveillance.  Involved in the degradation of aberrant polyadenylated pre-rRNA through 5'-end processing (PubMed:20338880).
What are the official names of this protein?
5'-3' exoribonuclease 2, AtXRN2, Protein EXORIBONUCLEASE 2.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCUP_STAA3
Sequence: MVHNKNNTILKMIKGEETSHTPVWFMRQAGRSQPEYRKLKEKYSLFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPIKTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMYRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYRRYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQLGVTKTLQGNLDPSILLAPWNVIEERLKPILDQGMENGKHIFNLGHGVFPEVQPETLRKVSEFVHTYTQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_PSE14
Sequence: MKTGKELKPGTVIRLENDPWLVQKAEFTKSGRNSAIMKTKLKNLLTGYKTEIVYSADDKLDDVILDRKEATLSFISGDTYTFMDTTDYTMYELNAEDIESVLPFVEEGMTDVCEAVFFEDRLVSVELPTTIVRQVDYTEGSARGDTSGKVMKPAKLKNGTELSVADFIEIGDMIEIDTREGGSYKGRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPM_COXBU
Sequence: MTKQIIKGIIIERSSPLKIDELSQAVHLRREIIIEMVEHRLIEPEGSSPTSWKFDNVCLKRAKIAASFYRDLEINMPGIAIALDLLDKIEHLEQRLRTLERFENQE
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: TRPC_AFIC5
Sequence: MSDILQKIERYKREEIASAKAAHPQAEVEAAARHAPALRGFAKAIRDRLAHKQFALIAEIKKASPSKGLIRADFDPPALARAYEAGGATCLSVLTDTPSFQGHLDFMVAARAATSLPVLRKDFMYDTYQVMEARAHGADCILIIMAALDDAAARDIEAAALDLGMDVLLEVHNEPELERALKLRSKLLGINNRNLRTFETTLATSEALAASVPNDRIMVGESGIFTPADIARLARVGIETFLVGESLMRQTDVTSATRTLLAKAS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MDM4_XENLA
Sequence: MSTSTALHLMDEQDPAPTTIQNTEESLVRVQPALLKILQSAGAKGDMFTLKQVMHYLGQYIMVKGLYDKQHQHIVHCGSDELGKLLGITTFSVKDPRPLYDMLKKNLLRISCTDAGHSPSRNKSQASDSLELEKSFASKTEVTDVIKRNDCVSSDMCTSFDNSHLKGNESSDYTKQSLDFIFEEWDEAGLPWWFLGNLRTNYNLQSIGSTDIPSNQDIDTATVSDTTDDMWFLNDSRTDRINMEVKMESSDSLEEEVGECDSKKPAQMIELTLYEDDDDLDDTQSLSEDTDTEVTSEECWQCTKCHKFNSPVKRYCYRCWALRKDWYLDFPRLIHSSSTPTLPGKVSSQMIVDGLDIPDCRRTVSAPMVGVQVPECRSLVPFLEPLDLAANSKAFSESTDTLLTFKAAEASLLSSRPLLEPCQLCQRRQRNGSVVHGRTAHLVTCFSCACNLKKNQKGCPVCEKPIQMVVKIYVA
What is the function of this protein?
Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
What are the official names of this protein?
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Mdmx protein, p53-binding protein Mdm4.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CD80_RABIT
Sequence: MGHTLRPGTPLPRCLHLKLCLLLALAGLHFSSGISQVTKSVKEMAALSCDYNISIDELARMRIYWQKDQQMVLSIISGQVEVWPEYKNRTFPDIINNLSLMILALRLSDKGTYTCVVQKNENGSFRREHLTSVTLSIRADFPVPSITDIGHPDPNVKRIRCSASGGFPEPRLAWMEDGEELNAVNTTVDQDLDTELYSVSSELDFNVTNNHSIVCLIKYGELSVSQIFPWSKPKQEPPIDQLPFWVIIPVSGALVLTAVVLYCLACRHVARWKRTRRNEETVGTERLSPIYLGSAQSSG
What is the function of this protein?
Involved in the costimulatory signal essential for T lymphocytes activation.  T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
What are the official names of this protein?
T-lymphocyte activation antigen CD80, Activation B7-1 antigen.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PSBY_SYNPW
Sequence: MDLRLVLVASPILLALGWAGFNIGRAAVGQLQLMIKRSRA
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: UHPT_ECO57
Sequence: MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTFLGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPESYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRIGIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIALALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERKIRREKKIQQLTVA
What is the function of this protein?
Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate.
What are the official names of this protein?
Hexose-6-phosphate:phosphate antiporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VIP_RABIT
Sequence: HADGVFTSDFSRLLGQLSAKKYLESLIXXXXXXXXXXXXXXXXXHSDAVFTDNYTRLRKQMAVKKYLNSILN
What is the function of this protein?
PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin (By similarity).  PHI also causes vasodilation.
What are the official names of this protein?
VIP peptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: SIP5_ASPCL
Sequence: MGNSQTKESRPSLSSSNRRGHQWGSSSSHGRSPYGDRHHAEGSRSRGSRPDLSMFGIGGSSDRDVATLEHRRETKQEREARRLEKERVARLKERERSMREEHVDGGYLVTQGVYVGTEDFNKAVTRQLMIERRLAPFWRGLNDFSDSWTEHQLMAAARGLPIPPPDEIPPELEYKNPPRSTEEAKESTIQHLMVPITSRSQSYGSEASQSSTPTHSLPSPTSPFASGTSSSPLFRTRAKTLASLTSSRHGSQVDAGPKEIQLPKDPFVNGQPIEAYLYKDATECPICFLYYPPYLNRTRCCDQPICSECFVQIKRPDPHPPEHGETDSNAANSTSDRDRQESQDGQLVSGPAACPFCVQPEFGVTYAPPPFRRGLVYATDSSLRPTFASPVSSSSSLSSANPPAITGRRRATSLSANDPTVITTDRIRPDWAQKLANARAHAARRSAAATALHTAAYLMNTNSSGNESRNFSLGRRGVMRRTGTSENQSVSNRSGSPALQALAFLTDRRAVGPETDFAEEGGGNMAPPRNSSRRNRIDDLEEMMMMEAIRLSLASEEERRRKEEKEAKKEAKRREKESKKAEKAARKLGVYSNNASSSALDVLSDPRHGKGSSSSSSMTGEDTACGKGKEVERMPPSTTNATASPSSLEIPSDAANSSPVAHVIEPGSSAQAATTQSLARELPKPSHLRHVSSASSSFSSLVDSTPDDPTGAYDGSATATEPMFNFRSLAAVIGDEDKGVESTEHVEDTSSRATVASSASGVAPSATETSGAPATGVEPVSVETITENGDCLMPKELETRSVEITHTAPNTEATS
What is the function of this protein?
May negatively regulate the snf1 kinase.
What are the official names of this protein?
Protein sip5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y068_MYCPN
Sequence: MEKKKLPFGLKNKEKLTAYNDEKIHELHRQLKAKIEAKKAKEKQDSKTKDTDKKVDQTPKVKVPFTKKFSNLWFGIDKEVNKIVWVTSKKLITIFLLIVLVSAIMIGIYFGINHLFIALGVFKGK
What are the official names of this protein?
Uncharacterized protein MG055 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UNG_CAMC5
Sequence: MQVNLEDVKIEPSWKEALKGEFLSLYFGDIKEKLICAKRAGIVYPPSNLIFNAFNLTPFDTVKVVILGQDPYHGPNQAMGLSFSVPNGVRIPPSLVNIYKEIYDDLGIREPNSGDLTYWAKQGVLLLNASLTVGANMANSHSGFGWQIFTDAVIKILSRERENIVFLLWGNPAKAKIPLIDTNKHLVLTAAHPSPLARGAFFGCRHFSKTNFYLTQHAKTPIDWDLNNFQI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCDC6_HUMAN
Sequence: MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP
What are the official names of this protein?
Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=May be a cytoskeletal protein.