PharMolix/UniProtQA huggingface dataset:
Protein: COAD_OPITP
Sequence: MRHCIYPGTFDPVTYGHLDVLARAVKLFDHVTVAVAENTPKGPLFTSAQRIAMLQPNVTRFPNVSVTSFNSLLVEFAMAQKAIAVIRGLRAFSDFEFEFHMALMNRHLESQIETIFVMPNEQFSYTSSSLVKDVAKHGGDVSHFVPPNVAAALEAVFGTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSB_MYCLB
Sequence: MTEPDVEISSVLTGEDTLVLASMDTPAEIELVMDWLCQQRNRNPDIKFDVLKLPSRNLAPAALTALVEQLESDEDRSVVPVRVFWMPPAERSKLAKLAGLLPGRDPYHPNRRQQRHILKTDARRALVIAGDSAKVSELRQYWRDTTVGENECDFAQFVTRRAILAMERAESRILGPQYKSPRLVKPEILASTRFRAGLEKISGATVEEAGKMLDELATGWSRASVDLVSVLGRMLSRGFEPEIDYDEYQVAAMRAALEAHPAVLLFSHRSYIDGAVVPVAMQENRLPPVHVFAGINLSFGLMGPLLRRSGVIFIRRNIGDNPLYKYVLREYVGYIVEKRFNLSWSIEGTRSRTGKMLPPKLGLLTYVADAYLDGRSEDILLQPVSISFDQLHETAEYAAYARGGEKTPEGVAWLYSFIKAQGERNYGKIYVRFPEAVSMRQYLGAPHGALVQDQDAKRLALQKMSFEVAWRILCATPVTATALVSALLLTTRGVALTLDQLHHTLQESLDYLERKQTPVSKSALRLRSREGVRAAVDALSSGHPITRVDSGREPVWYITPGNEHAAAFYRNSVIHAFLETSIVELALAHARHVEGDRMKVFWAQAMRLRDLLKFDFYFADSAAFRANIAEEIAWHQNWEDRVSGDGDDIDAMLLTKRPLISDAMLRVFFEAYDIVADVLRDAPADVGQKELTELALGVGRQYVAQGRVRSGESVSTLLFATAYQVVVDQNLIAPAPDLAERRMVFRRELRDIRRDFDYVEQIARSRFIVREFKSR
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: WAPL_SCHPO
Sequence: MKRGKCKEKDNGLKRISSESEVWNFLDVTVSELNKQKRSPGQTVSKRLHKKQRVVSNPDLSLPSSPVKQILRNGLQNSKYGSHKTGLERSASCSSIDASANHSSTTYREQRSYLMEEGLDTQPIVPREVSSGRELDSTNHTIGTERAFLIEEDVSEDDEIQMKSIHELRFAGEQQRIVDEIEYLVDGVTFSGNSSASRYLSLIGIAEKMFDNSFRLCLKSIRDVFLRIFEEIDPKDTLHTFLQIYIFATMANEMDCMSSLLDAYSNNVKLLLQTAITLEPQVPVSILAKSLPKSVKGAVQEFVIKAELTFSFSNESLASSDSISLAAIALMKTSSGVFAESELFTELINLLIEKSYPILKENDGSNNFLLHALCSSLEKFTDFQGSEKIQKVSQILSSKLQILIDEHNETNSPKIDDTVVHACSEKLLRTLIQTVNSNSDHALAVSKSEVPLFAYKILQKFSNFSSDDETTRELIILILGLLLGLVEESHEFIQTITHVEVSFGASALDVLISFYQKNESIVEISGYVVMILSHCFLNDPKAFAQLKPLISQFYESLHKFKNFHLKLKEELMMMGSNGLAIVSIIDELHKSLQDYLRSDLVK
What is the function of this protein?
Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin.
What are the official names of this protein?
Wings apart-like protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the WAPL family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TOP1_CHLAE
Sequence: MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKDKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDIKKEKKRKLEEEEDGKLRKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.  Involved in the circadian transcription of the core circadian clock component BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the BMAL1 promoter.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli.
Protein: TRMB_YERPE
Sequence: MINDVISPEFDENGRALRRIRSFVRRQGRLTKGQQLALDSYWPVMGVEYQAAPVDLNTLFGREAPIVLEIGFGMGTSLVTMATNNPQQNFLGIEVHSPGVGACLSSAHDAGLSNLRIMCHDAVEVLENMIPEASLDMVQLFFPDPWHKARHNKRRIVQTPFVELVKSKLKVGGVFHMATDWQPYAEHMLEVMSGVSGYLNLSEQNDYVPRPDSRPLTKFELRGQRLGHGVWDLMFERKE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: GAE3_ARATH
Sequence: MKQMSHLDDIPSTPGKFKPYFHRTRWQSSVAKLAFWSLVFVGLIFIFFYRSPVSSNPADPSRRSLRTYSWGGPAWEKRVRSSARLRTRRGFSVLVTGAAGFVGTHVSAALKRRGDGVLGLDNFNDYYDPSLKRARQALLERSGVFVVEGDINDAALLKKLFEVVPFTHVMHLAAQAGVRYAMENPSSYVHSNIAGFVNLLEVCKSANPQPAIVWASSSSVYGLNTKVPFSEKDRTDQPASLYAATKKAGEEIAHTYNHIYGLSLTGLRFFTVYGPWGRPDMAYFFFTRDILKGKAISIFEGVNHGTVARDFTYIDDIVKGCLGALDTAEKSTGSGGKKRGAAQLRVFNLGNTSPVPVTDLVTILERLLKVKAKRNIMKLPRNGDVQFTHANISSAQRELGYKPTTDLQTGLKKFARWYLGYYNGGKKAAS
What is the function of this protein?
Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components.
What are the official names of this protein?
UDP-glucuronate 4-epimerase 3, UDP-glucuronic acid epimerase 3.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Protein: CH10_BACC0
Sequence: MLKPLGDRVVIELVQAEEKTASGIVLPDTAKEKPQEGKVIAVGTGRVLENGERVALEVAAGDLIIFSKYAGTEVKYEGTDYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX21_TITDI
Sequence: KDGYLMGADGCKLCVLTAPYDYCACE
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  This toxin is active against mammals and crustaceans.
What are the official names of this protein?
Toxin TdII-1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PVK1_GONGO
Sequence: QGLIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_RABVU
Sequence: MDADKIVFKVNNQVVSLKPEIIVDQYEYKYPAIKDLKKPSITLGKAPDLNKAYKSVLSGLNAAKLDPDDVCSYLAAAMQFFEGTCPEDWTSYGILIARKGDKITPDSLVEIKRTGVEGNWALTGGMELTRDPTVPEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFIKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQVRSLNATVIAACAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQEYETAELTKTDAALADDGTVNSDDEDYFSGETRSPEAVYARIMMNGGRLKRSHIRRYVSVSSNHQARPNSFAEFLNKTYTSDS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CIPKP_ORYSJ
Sequence: MFRSMGTGTGTKPPAMTTERYEFGPLVGEGNFAKVYLGRHRATGEEVAIKVMDKEKLVRLGATELIKREIAVMQRLRHPNVVRIHEVMANKRRICVVMEYVRGGALYRYFRRGPSGGAAGLREHEARRFFQQLVSAVAYCHSRGVFHRDIKLDNLLVDEQGNLKVADFGLSALADMERREAHLQTVCGTPLFLAPEVFKRRGYDGAKADVWACGVVLYVLLTGRKPFPDEHVSRLYRLIGQNQFQCPPSFSPDLARLVRRLLQPDPDRRITIPEIMEMRWFKRGFKEVTYYIDSNDRLRSLDGLDGEPELYDSDTDTIESSSSSESPTPVAGTPRGMHTSVSAPALSELDRMEDSASLPLPLPLPPRPRMPRPKSLNAFDIIASSPSFDLSGLFEERGERMRFVSGAPVADIIAKLQEIAGMVSFTARTKDCQVSIEATRNGQKGALAISAKVFELTRELVMVQVCKKAGDTAEYRRFCDNELKAGLRGLVVDALPPPVEGGGHGGAAAAAEAE
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 25, OsCIPK25.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: MDAR3_ARATH
Sequence: MAEEKSYKYVIIGGGVAGGYAAREFSNQGLKPGELAIISKEPVPPFERPELTKVYIDLEVNPTLANIYVCAGTGEAKQYPNWYKEKGIDLIVGTEIVKADLASKTLVSDDGKIYKYQTLLIATGSTNIRLSEIGVQEADVKNIFYLREIEDSDELALAMELYVQRGKAVIIGGGFLGLEISSALRANNHEVTMVFPEPWLVHRFFTAEIASFYESYYANKGIKIIKGTVATGFSTNSDGEVTEVKLEDGRTLEANIVVAGVGARPATSLFKGQLEEEKGGIKTDGFFKTSVPDVYALGDVATFPMKMYGGTRRVEHADNARKSAAQAVKAIKAGEEGKTIPDYDYLPYFYSRFFKLSWEFYGENVGESVLFGDNDPKSPKPKFGTYWVKDGKVVGVFLEGGTQEEHKAIAKVARAQPSVESLDVLSEEGLSFATKFYSTSL
What is the function of this protein?
Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process (PubMed:16146528).  Required for producing sufficient ascorbate to maintain the interaction between Piriformospora indica and Arabidopsis in a mutualistic state (PubMed:19386380).
What are the official names of this protein?
Monodehydroascorbate reductase 3, AtMDAR3.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_NITHX
Sequence: MQAVNIIRWIDGPVLVGDSPGSKPPSERLQDTMAVSDPPVEAAGEASATRSGFWALTLGSIGVVFGDIGTSPLYAFREAVSHAAQQGTVTPVIVLGVLSLILWSLFIVVTAKYVLLLLRADNNGEGGTLSLMALGQRALGRQSLLLLALGVVGASMFIGDSMITPAISVLSAVEGLKLAAPEFGNYVVPLTLLILVMLFAVQSRGTASVASAFAPVMALWFVAIAVLGALHIHEDPSVLLAVNPWYAIHFLLNHGLIGLVIMGLVFLSVTGGEALYADLGHFGRKPIQAAWFCLVLPALLLNYFGQGALILAHPDAIENPFYRLAPAPMILPLVILATAATVIASQAVITGAYSLIRQAVQLGLLPRFEVRYTSETHAGQIYLPRVNILLLIGVLLLVLLFRTSSGLASAYGIAVSTTMVADGIMGFVVVWKLWNWRAATAAALVVPLVVVDIMFFSANLLKLLDGAWVPLLFGLIMVVLIWTWRRGAAILIKKTRRTEVPLLDLIKSLEKRPPHIVKGTAVFLTSDPNFVPTALLHNLKHNKVLHEHNVILTIETAQTPRVDPSERVRMENISEKFSTVSLRFGFMESPNVPKALVIARKLGWQFDIMATSFFVSRRSLKASAQSGMPVWQDRLFIAMSRSANDAINYFQIPTGRVVEVGTQVII
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: K5_VACCC
Sequence: MGATISILASYDNPNLFTAMILMSPLVNADAVSRLNLLAAKLMGTITPNAPVGKLCPESVSRDMDKVYKYQYDPLINHEKIKAGFASQVLKATNKVRKIISKINTPRLSYSREQTMRLVMFQVHIISCNMQIVIEK
What are the official names of this protein?
Protein K5.
What is the protein family that this protein belongs to?
Belongs to the poxviridae K5 protein family.
Protein: PHS_PSEPG
Sequence: MNALNQAHCEACRADAPKVTDEELAELIREIPDWNIEVRDGHMELERVFLFKNFKHALAFTNAVGEIAEAEGHHPGLLTEWGKVTVTWWSHSIKGLHRNDFIMCARTDKVAEVAEGRK
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: YCIB_PHOPR
Sequence: MKQLLDFIPLIIFFVLYKTNDIFVATGALIIATAVQVAVTWFLYKKVEKMQLVTFAMVTVFGGLTLFLHDENFIKWKVTIIYAIFSIGLAVSQIMGKPLIKSMLGKEITLPDTVWTRINMAWTGFFAVCAVVNIYVAFTLPLDVWVNFKVFGLLALTLIFTLVTGGYIYHHMPKETDSE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIG_SALAR
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGEDFTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADAEDRVTLDFTGTVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKVGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMERELKGAVRNRVKSQAIEGLVKANDIDVPSALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEVRVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAIEAVLAKAKVSEKATSFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: BRE1_DICDI
Sequence: MSMDHQDLKRRDPPADSESQRPSKKISLSSSEASVPIGGPPIDQNLILFQNRAMKVRVEEQKIEINDREQKIKQLNTKIHQYKENISCLCRVWDQLNSGLDLLINRVDFENAMDNLLPKDNITESFEFLSSYITEPVTLDEKYTLDQSLQKKVQKTQSTFSKISKALEKEHTLSKFVFRLLKSKDGIKSNDIEKLLKEDNDKLSKQNQYIQNIYDKVQIQFKQLTDQTTHLADQAAIYQQNNKELKLELEKSQDELTIERKRVIKLQDETLRTPQVKIPSPSLGSNIPGGANNNNNNNNNSNNNNNINNNGNNMGGSGSSSLASSTNGINKQQSNDINGKELTHEELIAELQRQSDSRLLEARKLREEKAILLKELQQIQIDIRVIPEERIQNSMPYQVLRQRYQLVSDELDIHRNQCTKLQNDLAQATIGRRLEREALEAFEAHRRQNIERRVSQLEVESIELKGEKEKLVCLIEQRNPNVPSLQYIQESRLLLDKKDDEIKQLRKEIEQLKLDIEKYKAPKEEIERYKLLVQRDVESKNIEINKLLEKINTITKQNNDLKSNEQQLLQKESELTLSLNILKSNKNNININNLDKDNIEDNSKIKQQQEQQQQQHQKIDNNNKKEEEIKKEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEEQKKDKEMIDIEKSTENIINNNNNNNTNEQKLNEINKNIENGNNENNNNNENTINNENTINNNNNENKDKIIFNLELNESKLKLELSTVKKQLEDITKSKEEYDNEIKEINEKFKAQIKELDITISQNKIQQESQKQELEALVMEIDSMGKAYEQMLEQNTRLTKQLSDKEDTHAHLMAENIKSQQTIRNSKEIQLAIEEKLNRNEEKLKSQGELMQKIEEKSNILQKQLSKVTEDLHSCSFDLEKHKRFVRENNAHSLELKTQLDHLSNLNAELKKKADDSIFALEREIDKAKRLDEEKQLLKKKLEKATSANNNNNNNNNNNNNNNNNNSSSSEEELKLINQRLRCTICNDRQKNYVIAKCFHVFCKECIYSNIDTRKRRCPSCNRAFAETDVHQIYY
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase bre1, RING-type E3 ubiquitin transferase bre1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MINC_BORPD
Sequence: MTTDSLALDFKSATLYAIRVVLHDADLDRLTAALDQRMADAGSFFENEPVVVDASRVDDPIDWPALLAALRGHNLPPIGVVAEGANLAAAQAAGLAAVELSTPPARPAPAVETAPPNDAATPVPAVPAAALETGASATTGNAPAEPAPAEPAAPAAAPQPPAVPAPASALVITKPLRSGQRVYARHTDLVVIGMVSQGAEVIADGNVHVYGPLRGKAMAGARGDTSARIFTTQLDAELLAVAGVYRVVEDKLDSTLHNQPALVYLDGETLRVEALKR
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: TAT_SIVVT
Sequence: MDKGEAEQIVSHQDLSEDYQKPLQTCKNKCFCKKCCYHCQLCFLQKGLGVTYHAPRTRRKKIRSLNLAPLQHQSISTKWGRDGQTTPTSQEKVETTAGSN
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: COXX_ACIC1
Sequence: MTALAPSSTPLPAGRRGAVDIVKGLIALTKPRIIELLLVTTVPTMMLAARGWPSSRLVVVTVLAGALAAGSANTLNCFIDRDIDQVMRRTARRPLVRSVIRPAEALAFGVALGVVATLLMGFLVNWLSAILADAAIVFYVGVYTIGLKRRTPSNIVIGGAAGCFPVLIGWSAVTGRVGWPAVVLFAVIFAWTPPHFWALAMRFREDYAAAHVPMLPVVAEPLVVARQILWYSYGMVAASLALAPVAHVGWVYVAIAALLGGWFLAEAHRIVQRVRLGRDPRPMRLFHMSISYLTLLFVAVALAPYLP
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEGLB_XENLA
Sequence: MAGSLVESEALQMGVRRLSSPLTSPVQAEVYFPRLTVPFCGHIKGGLRPGKKILIMGIVNLEPKNFDIRLTCGDSEDPAADIAIELRAEFSDKQFLRNARVSGKWGEEESSIAYFPFIADQPFRVEIHCEHPRFRIFVDGHQLFDFYHRVESLSAINTIKINGDLQLTKLG
What is the function of this protein?
Does not bind lactose, and may not bind carbohydrates.
What are the official names of this protein?
Galectin-related protein B, Lectin galactoside-binding-like protein B.
Protein: HSLV_BAUCH
Sequence: MTTIISVRRNGHVVIGGDGQATIGNTIMKGNVRKVRRLYYNDKVIAGFAGGTADAFTLFELFERKLESYQGHLVKAAVELAKDWRTDRRLRRLEALLAVADENASLIITGNGDVIQPEKDLIAIGSGGPYAQSAARALLENTNFSAREIVKKSLVIAGDICIYTNQFHTIEELTSTAEGY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_ECO24
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ADDA_LIMRD
Sequence: MAGFKPTPAQSKAINDRGENILVSASAGSGKTAVLVNRTIELIKEGQSIDRMLLVTFTDAAAKNMRDKIRAALQKIVQDSANPKDLRDRMSNQINRLAAADISTIHAFCLKLIKRYYYLIDLDPQFRLLTDETERLLLQEDVWHEVSEELYRNAEEKVSGKASFSELVLNFSSDRDDQGLDDLILRLYEIANAQPDPEKWLQKLPDNYDLGSGSLLESNFYQQQLKPLVIEKLNQFIQDYRELVTRASDNGLDQAAEVIKSDEELMHQLLSSLGGITVSDVCQMMAQQKFGSFRGRPAADDPRIDVFKDIQKQRNQLKKQWEQMVSTYLGKQEAQEPIAKEELLTELTTFSDQFTDLLSKATESQLDAKTVDSLQKDQQMMQELLDLLQPPTWNTIRDLFANAKFARMGGKPKDDELAEEVYKSLGSARTGIKKQFDQLVDRFFNYREDQFRLISTHAQELLRELSAVTINFRRRYQQTKLNRHVLEFSDLEHYAYAILTPPDDQPNWQTLVKDLQNHYQEIMIDEYQDTNRLQESILMKLTSPERKNLFMVGDVKQSIYRFREADPTLFLGKYQNYRQGSDGEAIVLGENFRSMTNVTSFTNILFEQLMDREVGEIDYDEDAHLKYAATYYEENQDNKVHPTEVLLYDANALDPEKEDVEHEDDKLAGEFRMIGMRIKQMVENQELIFHPEDGQMHPIQYGDIVLLERTKAINNSLMEEFNKLNIPLTVHDVESYFQATEVRVMMSLLKIIDNPQQDIPLVAVLRSPIVGLTNQELAFIRLQNRSVDYYAALQTFMSNYQRKALRHQSLLTSEQVNALYEKADHFLGLLRVFRQTAQQQTLVDLIWQIYDQTGYLDYVGAMPGGHQRQANLHALYQRAHSYEQSSFKGLYQFIRFIEKMQEHDKDLGVAPTQLTANTVNVMTIHGSKGLQFPVVFLIDATHGFNKGAARENAVVDAVAGVGIRYMDDQRVIYDTPQRQAVIEEIQRGERAEDLRVLYVALTRAEQRLVITGSFNEEMRTQSLAGSWQRWQKAYQSKNLLIGPQPRITANSFMDWVGLALARYPEFNAQQLSRGNVTLEESTLADTKVTGLAADPHFTAKTYTALDVSDGLAKIGQNASANVTEKNNTVATDASEQKIEQILRYRYPHLVATKTTAYQSVTDVKRVFEDPDTRDMARWDYDQQQKVKTQGIYLNNNFDVPAFIQQTTHEPVATEIGTATHLVFQKLPLDEGLINVEFVDQEIQKLVGEKLINPVVAARINREGIVAFYQTAVGQKILKHPADYHREVPFSMIMNGHELFKGVNVSDDERILIHGIIDGYLRTDEGIILVDYKNDHLNKDYRDFDLARIKDRYRGQLELYKEALNLMEGIPVVQMGLYLLELGEFVLFTKEGD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.