PharMolix/UniProtQA huggingface dataset:
Protein: CCD78_MOUSE
Sequence: MDQRPELLSSMEYVASPDPKPGVPLRVAENVAPGAEDWLPSASGHLAWATSLETEHQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREILRLESRVLELELHGNGACQGHKVQPMANLGQHQVPPLEPPGGQQKLQEELKWLLEHHRARQQALETQVGVLSQQLQGAREEARTTGQQLASQAMVLASCKGQLRQAEAENTQLQLQLKKMNEEYAVRLQHYARETVENASSTNQAALQAFLESTLQDIRAAHRTREQQLAQAARTYRKRLADLNQRQELLLTTCRATFATAINLEPLPMHWATELSHPRENEYGRHRTLLLYPEKGSGETSKENKSQPLALDTASWAQIQQRLQDFSQDTQAELERERAQLMVRATMAEQQLSELQEYVDQHLGRYKQEILKLRKLVNIGDPQGVEAVSSPGSGGARL
What is the function of this protein?
Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase.  Essential for centriole amplification and is required for CEP152 localization to the deuterosome (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 78.
What is the protein family that this protein belongs to?
Belongs to the CCDC78 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, perinuclear region. Cell membrane, sarcolemma. Sarcoplasmic reticulum. Note=Localizes to centrioles and deuterosome. Found primarily in the perinuclear region as well as along the sarcolemmal membrane and in reticular pattern within the sarcoplasm (By similarity).
Protein: RNZ_STRPC
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: GSA_DESHY
Sequence: MGFQDQRSKEAFARANGVLPGGVNSPVRAFKSVGREPIFIAKGQGARLWDIDGNSYLDYVLSWGPLILGHAHPVVVGAIKAAAERGTSYGAPTEIETECAEEVIKAFPSMEMVRMVSSGTEATMSALRLARGVTGRNKIIKFEGCYHGHGDSLLIKAGSGALTFGVPTSPGVPSSVASQTIVAQYNDLEGLKEIFKECGEDIAAVILEPVTGNMGVVLPQPGFLAGLRTLTQDYGSLLIFDEVMTGFRVSYGGAQGRYQIDPDLTCLGKVIGGGLPVAAYGGKRKYMEQVAPSGPIYQAGTLSGNPLAMAAGLATLKLLQQEGVYEGLEKKTTRLAEGLQSIAQELGFPIWVNSVGAMFSAFFTDQPVIDFKSACSSDVERFGSFFRGMLERGIYLAPSQYEAVFLSAAHTDADIDYTLEQARDVLKSLG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STAA2
Sequence: MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIRTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: E4PD_SALHS
Sequence: MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGVYGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAVGFRLDASASTKL
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_RICAE
Sequence: MKRTFQPSNLVRKRRHGFRSRMATPTGRAILRKRRAKGRHKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: VEL_COPC7
Sequence: MSNTDAQTSFASLVVGPPVTDPINPLMGATSISPNLIELHGRKALVFAFGNLAVRAEGDFVLRYRVADILAGTGIDGVFPIQAICYGGPFHVFSTKDFPGYEASTELTKTLSVWGAQVNVREHRRRRRGKKDAAPAVTKPLYTTAPLDRDIVADSERRRRRRAGY
What is the function of this protein?
Velvet-domain-containing protein that probably acts as a positive regulator of sexual development.
What are the official names of this protein?
Probable velvet family sexual development regulator CC1G_12219.
What is the protein family that this protein belongs to?
Belongs to the velvet family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_CITBB
Sequence: MSERGNRKTQVGVVVSDKMDKTAVVKVDRLVKHPVYNKYIKRSAKYKAHDMDNAAKIGDRVLIVETRPLSKDKRWKIRQIIESKG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RNFA_COLP3
Sequence: MTDYLLLLVGTVLVNNFVLVQFLGLCPFMGVSSRTETAIGMSFATVFVMTLASLLSYLVTTYLLVPLNLEYLTTMSFILVIAVVVQFTEMVVHKTSASLYRLLGIFLPLITTNCAVLGVALLNLRLQHGFFESIIYGFGAALGFSLVLIMFSAMREKLANADVPAPFKGTAIAMITAGLMSLAFLGFTGLVKI
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TXS4C_CUPSA
Sequence: FLAKKVAKKLVSHVAQKQME
What are the official names of this protein?
Short cationic peptide-4c, SCP-4c, Short cationic peptide-4e, SCP-4e, Truncated variant of Cupiennin 4 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 04 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALLD_ECOLI
Sequence: MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
What is the function of this protein?
AllD plays a pivotal role as a metabolic branch-point enzyme in nitrogen utilization via the assimilation of allantoin (PubMed:10601204).  It is able to utilize allantoin as a sole source of nitrogen under anaerobic conditions (PubMed:10601204).  Catalyzes the oxidation of ureidoglycolate to oxalurate (PubMed:23284870).
What are the official names of this protein?
Ureidoglycolate dehydrogenase (NAD(+)).
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_CITK8
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHDGRHLLPSVVHYQQQGHTVGYAARANAAQDTANTISSVKRMMGRSLADIQTRYPHLPYQFQASENGLPMIETAAGLLNPVRISADILKALAARATEALSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADSVSVNVAGWQGDITREQFNDLIAALVKRTLMACRRALKDAGVEAQEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGLPAMPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIATMIQDSMSFAEQDVKARMLAEQKVEAARVLESLTGALAADAALLSAAERQVIDDAAAHLSEVAQSDDGDAIEQAIKNVDKQTQEFAARRMDKSVRRALQGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y0572_MYCTO
Sequence: MGEHAIKRHMRQRKPTKHPLAQKRGARILVLTDDPRRSVLIVPGCHLDSMRREKNAYYFQDGNALVGMVVSGGTVEYDADDRTYVVQLTDGRHTTESSFEHSSPSRSPQSDDL
What are the official names of this protein?
Uncharacterized protein MT0599.
Protein: CYSH_ALKCK
Sequence: MAYVFEQMEATDYEKVNTKLKNRDSLDILRWANQTYGEKLVYACSFGAEAMVLLDLLSKIQKEAHILFLDTDFHFAETYELIERVKERYPTFRINMAKPALSPEEQAERYGDELWLKNPDQCCQIRKLDVLARELEPYDAWLSGLRREQSPTRANTEFVNQDKRFKKVKVCPLIHWTEEEIWMYIKLHQLPYNELHDQHYPSIGCTYCTKAVMPGEDARSGRWAGTGKTECGLHAPTKGDS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_BURCH
Sequence: MNDTTHATDAAHSPHSTQQHSMRALAIAAIGVVFGDIGTSPLYSLKEAFSPAHGIPLTEGSILGVISLLFWAILLVVGVKYLLFVMRADNNGEGGVLALMALSLRPLDSKTRVAGALMALGIFGACMFYGDAVITPAISVMSAVEGLEIATPHLSHLVLPITIVILIALFWIQRHGTALVGKLFGPIMVLWFVVIAALGVYHIVRVPGIIAAINPYYAASFMADHLLQAYVVLGSVVLVLTGAEALYADMGHFGAKPIRYAAYGLVMPSLVLNYFGQGALLIQNPKAIENPFFLLAPEWGLLPLVVLSTVATVIASQAVISGAYSLTSQAIQLGYVPRMKVLHTSELAIGQIYVPVVNWLLLAVILCIVVGFKSSDNLAAAYGIAVTATMVITTVLACVVMVKVWNWNRLLVGAIIAVFLAIDLGFFGANLLKVAQGGWLPLGIGALLFFLLMTWYKGRHIVKERTAADGIPLEPFLQGLLAHPPHRVSGTAIYLTGNDKLVPVSLLHNLKHNKVLHERTIFLTFVTRDIPYVRDDKRQSARDAGGGLYIVKAEYGFNETPDVKAVLEEFGRTHDMTFELMDTSFFLARETVVPTHLPGMSIWRERVFAWMHQNAAKPTDFFAIPANRVVELGTKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOH_XYLF2
Sequence: MYIEVTGYGPALVLIHGWAMHSGVFAPLVEQLRPHHTLYLVDLPGHGYNHTTPTPLALPQVVHAIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLIMLAATPCFVRREDWPHAVEVSILTQFAQDLKQNYTETINRFLALDTLGSTHAQSELRQLRKILNARHTPNTATLQAGLELLAHTDLRRALIDLTPPSLWIAGQRDRLVPAASIQAATVLAPSDQTELLTITGGGHAPFLSHANQMTAALQHFIATLP
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPNC_SINFN
Sequence: MTSGSGPRSDAMHREKNFPVASWIIHPRHRALILAFYRFVRMADDIADHATLAPDEKLLYLDLLEAELLGKGETRAEAVHLRTALDRRGMPPRHALDLLTAFRMDVTKQRYENWDEVIDYCRYSAMPVGRFVLDVHGESAATWPASDVLCAGLQVCNHLQDCGKDFLNLNRVYIPRDALSASGASIEELGAAKSSLQMLQCLRSLAAKAEVLLNGGGALVSQVKDFRLRFEVSVILSFADKIVSMLKMRDPLRERVHLSPLELLLHGVGAMANEAARRAFGRGTRFKTTVDV
What is the function of this protein?
Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP).  Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ).
What are the official names of this protein?
Hydroxysqualene synthase, HSQ synthase, HSQase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. HpnC subfamily.
Protein: Y1309_XANOM
Sequence: MSVLPTPLANQLLIALPALSDPTFSRSVALICQHDENGAMGVLVNRPSEYTLGEVLSQMGIDTDDEPLREQIVLSGGPVHPERGFVIHDDAREWDSSLEVGQGVFLTTSRDILEAMAAGNGPRNVLVALGCAGWGAGQLEFELGENSWLTAPSDANVLFATALEDRWQTAAGRIGVDLFRLTDYSGHA
What are the official names of this protein?
UPF0301 protein XOO1309.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: UBIE_PASMU
Sequence: MTDQHAFATEQVQLDPTLSPTTEETTHFGFKTVAKSEKQKMVANVFHSVAGKYDLMNDLLSFGIHRVWKRFTIDCSGVRKGHKVLDLAGGTGDFTAKFSRLVGPSGEVILADINDSMLRVGREKLRNLGVVGNVNYVQANAEALPFPDNTFDCVIISFGLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPILDPLSKIYNFYSFNILPKIGEVVVNDSESYRYLAESIRMHPAQDVLKQMMIDAGFEQVNYYNLSAGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RBFA_FINM2
Sequence: MNIKRVRRISSEIKKVISSSIINSLKDPRIDKLNVSVTEVKVTNDLSFATVYIAVIGDDEKKKQTLEGLNKAKGFLKKQIGENVDLRHVPQLIFKIDETSEQSMHIENLIKSIHEENHNEN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFBX_SALTI
Sequence: MRKLRLVRIPRHLIIAASSWLSKIIIAGVQLVSVKFLLEILGEESYAVFTLLTGLLVWFSIADIGIGSSLQNYISELKADRKSYDAYIKAAVHILFASLIILSSTLFFLSDKLSSLYLTSFSDELKNNSGSYFFIASILFIFIGVGSVVYKILFAELLGWKANIINALSYLLGFLDVVAIHYLMPDSSITFALVALYAPVAILPIIYISFRYIYVLKAKVNFNTYKLLLSRSSGFLIFSSLSIIVLQTDYIVMSQKLSAADIIKYTVTMKIFGLMFFIYTAVLQALWPVCAELRVKMQWRKLHRIIFLNIIGGVFFIGLGTLFIYVLKDYIYSIIANGIDYNISGVVFVLLAVYFSIRVWCDTFAMLLQSMNQLKILWLIVPCQALIGGVTQWYFAEHYGIVGILYGLILSFSLTVFWGLPVYYMYKSKRLA
What is the function of this protein?
May be involved in the translocation process of the nascent O-polysaccharide molecules and/or its ligation to lipid A core units.
What are the official names of this protein?
Putative O-antigen transporter.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP52A_ARATH
Sequence: MSDISIDALGQTMGDFSNHEKLGFDLGAFVGDLAFEEDSGSEDISLEGLQQELEECESDEVVANILSSGDKLREYAKGVENNLRKVELDSIEDYIKESDNLVSLHDQIRDCDSILSQMETLLSGFQEEIGSISSDIKILQEKSMDMGLRLKNRRVAESKLAKFVEDIIVPPKMIDVIVDGEVNEEYMKTLEILSKKLKFVEADQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQQSVLLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFRAYIQALEKLQLDIATAYDLIGVETRTTGLFSRAREPLKNRSAVFALGDRIKIIKDIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYMFCDDFFGEESIFYEIFAGPFSVIDEHFNPVLSNCFDAIGLMLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKMVFDSHLSSLRDANIKTLWEDDVHPHYVMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDGLILKLAKLFPRPKQQIVFLINNYDMTIAVLKEAGPEGGKIQMHFEEMLKSNTSLFVEELLVEHFSDLIKFVKNRASEDSSLNPERSITIAEVEPLVKDFGSRWKTAIELMDKDIITSFSNFLCGMDILRAALTQLLLYYTRLTDCIKKIDGGSALNRDLVSIQSIMYEIRKYSKTF
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity).  Required for pollen tube elongation and other polar growth.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 52 A, AtVPS52, ARE1-like protein POK, Protein POKY POLLEN TUBE, Protein T-DNA TRANSMISSION DEFECT 8.
What is the protein family that this protein belongs to?
Belongs to the VPS52 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=Localized in the GARP complex in the Golgi and post-Golgi compartments.
Protein: AMPG1_RICPR
Sequence: MLKNSHIYIIWLFGFISGFNVMITGNTLNYWFAKKDIALQTIGMLSFITLPYSINFLLAPVFDTVQIKYLNKILGHRLSWICLTSTTLISLIFILSFLDPSTDLVLLSFIAFIISFFSAAQDTILSALRTKIVPKESLGFTSGIYILGYRVGMLLASSGAIYLSIYLTFNAIYKIFAGVIFVYLILLILVARYTNSFDVMEENTSYSYVARCYAIADMNLKNKFFIKNYFNYFKNFISAYLLKIFSGFYFHRNDINLAYYIILILIFLVLYRLPDNLINVMINPFLLHLGYNAFEIASVCKFCGVMGAIIGGLIGGIIMKYKNILYSILLFGIIHALSHIFFILLEINGKNSLILFITIGVESITGGMTMTAYIAFISSLCQGKFRATQYSLLSSMMGISRSIFPIISGYMVVNFGWQNFFLFTTIITIPSLLILLKIKTKIN
What are the official names of this protein?
Putative transporter AmpG 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UEVLD_XENTR
Sequence: MEFSAETLRQQLGKYKFRDLTIEELKDLNRTFPSFIFSMETYTFRDGSQKDLLNLTGTVPMKHQGTTYNIPICLWILDSHPFAPPLCFLKPSGNMGIRVGRHIDAQGRIYLPYLQNWSHPKSTVTGLIREMAVKFEEELPLYSLSAEDGARQRELLSYIAQVTDGVSSMDVKAPSRAKVTVIGGGDMALACLLAVSAKGTAGKLLLLDPTDGEAAGGAAADLEIFSLPNVQVTKDFSAIAGSAIVIVTVNSWSNSQSYVGVLQSNVELLRGILPAVAHHCPKCLLLVASQPVEIMTYATWKLSGFPHNRVLGIGCNLDSGRFRHVIEKLADSEEGAQGAWIIGEQSDNKVAVWGAPDSSANRQTPCKLYPKIFQEQLTSRALEILKGKGQRSWSVGLSVADITDTLVQNKGKVHSVSALCKGQFGVQEEVFLSIPCVLGSAGVTGAVQTLQDEAQIWETLQRSAAAIESVQQQLRL
What is the function of this protein?
Possible negative regulator of polyubiquitination.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 3, UEV-3, EV and lactate/malate dehydrogenase domain-containing protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LDH/MDH superfamily.
Protein: TRHO_YERPN
Sequence: MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTLEDAKTFRDNLYSQFVKLGVFGRVYVAKEGINAQISVPANRYDEFKIALFASHPALDQVRLNVAHEDDGKSFWVLRLKVRERIVADGIDDDSFDPANIGHYLKADQVNQMIDDPDTLFVDMRNHYEYEVGHFENAIEVPSDTFREQLPMAVDMLQHDKEKNIVMYCTGGIRCEKASAYMLHNGFKNVYHVEGGIIEYARKAKEQGLPLKFIGKNFVFDERMGERISDDVIAHCHQCGTPCDAHTNCKNDGCHLLFIQCPVCAAKFEGCCSQICQEELKLPQEEQRSRRAGRENGIKIFNKSKGLLQATMHIPSPEKSADEK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MENH_SHIDS
Sequence: MILHAQTKHGKPGLPWLVFLHGFSGDCHEWQEVGEVFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAGLCGVIVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: BIOB_CHLPB
Sequence: MTVEMNKSIVKAYSVLETGEPLPFDVAVELAHLAGEDVPDLLSLANKVKNRYATLSEGALHSCSIINAKSGVCAENCRFCAQSLHNSADVEQYSLLDAEAIVRSAGDVYDEGIRHFGVVTSGYGYRKVNPEFLKIVAIIDQLRQEYPDLNVCASLGILGEEPVRMLAEHNVRHYNINIQVAPDRYSDLIADSHPLKDRIDTIRLLRKYGIPVCCGGILGVGETMRERLDFIYALQELDIAVIPLNVLVPIEGTPLQGAATPALTDIVKTFALCRLVHPGKIIKFAAGRETVMNDFQGLLMLAGANGFLTGGYLTTRGRKIGDDREFMRQLAGFAEVSCS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SULA_YERPY
Sequence: MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: BIOF_ACICJ
Sequence: MTTLDQFATDKLARLEAGALRRRLRPTARAPGAVLERDGQRLISFSCNDYLNLSTHPAVIDAAIDAARRHGAGAGASRLVTGDHPLYCALEARLAALKQTEDAVVFGSGFLANTGIIPALMAREDAIFVDELAHACIWAGARLSGAALHVFRHNDLAHLAELLAAHRQAARHAMVVTDGVFSMDGDLAPVGEMLALAKAHDAWLMTDDAHGIGVINEGRGSAHGHDVPLQMGTLSKAVGSYGGYLCASHVVCELIRNRARSFVYTTGLPPAVVGASIAALDLIATDPAMCAAPLAHARRFCAALGLPPAESPIVPLLLGTAERALAAQAVLEAAGFLVAAIRPPTVPEGTARLRFAFTACHAPDDIDRLAQLVHDRILVTA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RUVB1_DROME
Sequence: MKIEEVKSTVRTQRIAAHSHVKGLGLDEVGAAVHSAAGLVGQKAAREAAGIVVDLIKSKKMAGRALLLAGPPGTGKTAIALAIAQELGNKVPFCPMVGSEVFSNEIKKTEVLMENFRRSIGLRIRETKEVYEGEVTELTPVETENPMGGYGKTISNVVIGLKTAKGTKQLKLDPSIFDALQKEKVEVGDVIYIEANSGAVKRQGRSDTFATEFDLETEEYVPLPKGDVHKKKEVIQDVTLHDLDVANARPQGGQDVLSMMGQLMKPKKTEITDKLRMEINKVVNKYIDQGIAELVPGVLFIDEIHMLDLETFTYLHKSLESPIAPIVIFATNRGRCVIRGTTDIVSPHGIPLDLLDRLLIIRTLLYSTADMEQIIKLRAQTEGLQLEENAFTRLSEIGTSSTLRYAVQLLTPAHQMCKVNGRNQISKDDIEDVHSLFLDAKRSSKHLSEKNNKFML
What is the function of this protein?
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
RuvB-like helicase 1, Dpontin, Dpon, Pontin.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.