PharMolix/UniProtQA huggingface dataset:
Protein: NDK_MICAN
Sequence: MERTFLMIKPDGVQRNLVGEIIQRFETKGFTLVGLKMMQVSSELAEKHYAVHKERPFFRSLVDFITSSPVVAMVWQGEGVIASARKIIGATNPLNAEPGTIRGDFGISVGRNLIHGSDGPDTAKDEVSLWFSDAELANWTPAITPWVVE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_VIBPA
Sequence: MKPILPDYNSAGVLIIGDVMLDRYWYGPTGRISPEAPVPVVKVENNEERPGGAANVAMNIASLGGHAHIVGLTGEDEPAKVLTETLSALNVKCDFVALPDYPTITKLRVMSRGQQLIRLDFEDKFENTDATPVLSRMDAALPNVKAVIMSDYAKGSLEHVQAYIQKARAANIPVFIDPKGADFERYRGATLLTPNMKEFEDVVGKVKSDQELVEKALALVKEFDFEALLVTRSEHGMTLIRRGQEPFHLPTQAKEVYDVTGAGDTVISVLAASVAAGKSFEEACALANAAAGVVVGKLGTSTLSEIELAEAVHGSQDTDFGVISEKALIEAVKKARARGEKVVMTNGCFDILHAGHVSYLNHAAELGDRLIVAVNTDESVKRLKGPGRPVNPTDRRMAVLAGLGAVDWVVPFSEDTPQRLISEVLPSMLVKGGDYKPEEIAGGKEVIAAGGEVRVLNFEDGCSTSEIINAIKGGKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RR12_PINKO
Sequence: MPTIQQLIRNARQPIENRKKSPALRGCPQRRGTITPKKPNSALRKVARVRLTSGFEITAYIPGIDHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAAEVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHMP3_DANRE
Sequence: MGLFGKTQEKPPKDLINEWSLKIRKEMRVIDRQIRDIQREEEKVKRSIKDAAKKGQKDVCIILAKEMIQSKRAINKLYASKAQMNSVLLSMKNQLSVLRVAGALQKSTEVMKAMQSLVKIPEIQATMRDLSKEMMKAGIIEEMLEDTLEGMDDEEEMEEAAEAEVDKILFEITAGALGKAPSKVTDLPDPVAIGATAAPEEESEEEEEIEEMQSRLAALRS
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  Involved in late stages of cytokinesis.  Plays a role in endosomal sorting/trafficking of EGF receptor (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 3, Chromatin-modifying protein 3, Vacuolar protein-sorting-associated protein 24.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Endosome. Late endosome membrane.
Protein: PIMT_METAR
Sequence: MDRVPREEFVPEDVRPDAYYDTPLPIGHNQTISAPSMVAIMCQALDIREGNKVLEIGTGLGYHAAVMAVLAGASGVVYTVERIPELADMARSVLSRLGFDNVKVFLRDGTEGLPDFAPYDRISVAAAAPDVPQPLVDQLKDPGRLVIPVGRYFQQLMLVEKKGGQIITTDKGGVAFVPLLGKYGFKGY
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMR2_ANTEL
Sequence: MTTVSYVTILLTVLVQVLTSDAKATNNKRELSSGLKERSLSDDAPQFWKGRFSRSEEDPQFWKGRFSDPQFWKGRFSDPQFWKGRFSDPQFWKGRFSDPQFWKGRFSDPQFWKGRFSDPQFWKGRFSDGTKRENDPQYWKGRFSRSFEDQPDSEAQFWKGRFARTSTGEKREPQYWKGRFSRDSVPGRYGRELQGRFGRELQGRFGREAQGRFGRELQGRFGREFQGRFGREDQGRFGREDQGRFGREDQGRFGREDQGRFGREDQGRFGREDQGRFGRELQGRFGREDQGRFGREDQGRFGREDQGRFGRELQGRFGREDQGRFGREDQGRFGREDLAKEDQGRFGREDLAKEDQGRFGREDIAKEDQGRFGRNAAAAAKKRTIDVIDIESDPKPQTRFRDGKDMQEKRKVEKKDKIEKSDDALAKIS
What is the function of this protein?
Not known but it could act as a transmitter at neuromuscular synapses.
What are the official names of this protein?
Antho-RFamide neuropeptides type 2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDPA_SALTI
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS7_CAMJE
Sequence: MRRRKAPVREVLPDPIYGNKVITKFINSLMYDGKKSTATTIMYGALEAIDKKGGEKKGIDIFNDAIENIKPLLEVKSRRVGGATYQVPVEVRPARQQALAIRWIISFARKRSERTMIDKLAAELLDAANSKGASFKKKEDTYKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GLYA_GEOMG
Sequence: MSILETFDPAVAEAIRHETERQEYNLELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCHHVDVVENLAIERAKELFGADHANVQPHSGSQANMAVYFSVLKPGDTILGMNLSHGGHLTHGSPVNFSGRFFNVVPYGVSQETETIDFNEVERLALEHKPKLIVVGASAYPRVLDFAAFRAIADKVGALVMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGGMILCREEFAKTLNSNIFPGIQGGPLMHVIAAKAVAFKEALAPEFKLYQEQIVKNARTLADELMKRGFRLVSGGTDNHLMLVNLTGTELTGKVAEEALDKAGITVNKNTVPFETRSPFVTSGFRIGTPAATSHGLKEAEMVEVAAFIAEALANVGNEAKLAEVKGKVNALMGRFPLYASRLK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POC1A_XENLA
Sequence: MAGQSEDPSLERHFKGHRDTVTAVDFNANTKQLASGSMDSCLMVWNMKTQMRAYRFVGHKDAILSVDFSPSGHLIASASRDKTVRLWVPSVKGESTAFKAHTGTVRSVSFSGDGQSLVTASDDKTIKVWTVHRQKFLFSLNQHINWVRCAKFSPDGRLIVSASDDKTIKLWDKTSRECIQSFCEHGGFVNFVDFHPSGTCIAAAATDNTVKVWDIRMNKLIQHYQVHSGVVNSLSFHPSGNYLITASNDSTLKVLDLLEGRLLYTLHGHQGPVTCVKFSREGDFFASGGSDEQVMVWKTNFDAGSYPDLLKYRQNDTFPSGGDYTSIVQPADVHQPARNAHVTQAADLEPHITEMSVKDRSSPLSYTSRSVDQHHPQAEDGNLQTVASTLEHIVGQLDILTRTVGILEQRLSLTEDKLKECIEQQQATVPPSHSGTKKSSF
What is the function of this protein?
May play an important role in centriole assembly and/or stability and ciliogenesis.
What are the official names of this protein?
POC1 centriolar protein homolog A, Pat-interacting protein 2, Pix2, xPix2, WD repeat-containing protein 51A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat POC1 family.
Protein: RUVB_VIBA3
Sequence: MIEADRLIAPDNPVFKDEDVIDRAIRPKALADYQGQDHVRGQMEIFIKAAQMRNEALDHLLIFGPPGLGKTTLANIVANEMDVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGITQRLEYYKVEDLQNIVQRSADCLGLSMESQGALEVARRARGTPRIANRLLRRVRDYAEVKGDGHICPEVADKALNMLDVDAKGFDYMDRKLLLAIMEKFGGGPVGIDNMAAAIGEERDTIEDVLEPYLIQQGYLQRTPRGRIATDRAYLHFGIDKPSNR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YDHG_SCHPO
Sequence: MKFFLSLKDFKGEKFVLRSELDESSAFLCAISPTCRYVLRDEIPWKRLQRNVTSESLTDELIVDLLCGRSESKHTLQLVVLENLCRIYINYVDPFPLRIAWFELEQQALKDHEHFDVLWECSHSIKDLALASMAQQKNELQKLMAYTEQLQEECKSRERKLIMKFADMIKNARNNEDNEDNHHINYEDESDVGTDEQKQQEGVNSSAVSDTDESAVSDEFMQIKEEFPMKALSASPTADASPESAGEDDSHRRSSHESSETVSE
What are the official names of this protein?
Uncharacterized protein C6G9.16c.
Protein: COPA_HELPY
Sequence: MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFDENQTNLDEIFKLIEKLGYSPKKALTKEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLAIDNHSNFLNACLQLIGALIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQLYLVYTNHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKMQNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSGTFNSHTSFLMKATQNNKNSTLSQIIEMIYNAQSSKAEISRLADKVSSVFVPSVIAISILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGLFFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELLELLSLALSIEKSSEHVIAKGIVEYAKEHNAPLKEMSGVKVKTGFGISAKTDYQGTKEIIKVGNSEFFNPINTLEIKENGILVFVGRAISEKEDELLGAFVLEDLPKKGVKEHIAQIKNLGINTFLLSGDNRENVQKCAFELGIDGYISNAKPQDKLNKIKELKEKGQIVMMVGDGLNDAPSLAMSDVAVVMAKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANLMLSPAIAGLAMSLSSVSVVLNSQRLRNFKIKDH
What is the function of this protein?
Probably involved in copper export.
What are the official names of this protein?
Copper-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_POLAQ
Sequence: MNKDESRQRRARQTRIRIAEAQANRLTVIRSNTHISAQVYSPCGTKVVAAASTMEKDLRQAIKNGGNAQAAAQIGKLVAERAVKAGVVDVAFDRSGHRYHGRIKALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: VPA_BP186
Sequence: MTGVVYAFPWNAPRSAIASSYLTYDQQHRRDRMFAALLHARKVLFLQPECVRFDVYRTAAVLEQNQGSQRANAFLISFCKKALPRLELVAKKYECSGINSNVSAAVFDGHFDTQLMQYLASRMVNMVARFNRLPDMSRADIDLLAADIANFIRAELADIDDTGFSELKTLYTWYMRAGFISLQFNVTPPKWERVTKKYFCEDEIAPAVMRMFNEVWWRGRLRRIAAAWREHLQIAVGNVSKKRHAYASKNCVTDWREQKRRTREFLKGLDLEDEEGNRISLIEKYDGSVANPAIRRCELMARIRGFENICNELGYVGEFYTLTAPSKYHATTKAGYRNSKWNGASPSDTQSYLTGLWARIRAKLHREEIRIFGIRVAEPHHDGTPHWHMLMFMLPEDVERVRLIIRDYAWEEDHYELRSDKAKKARFHAEAIDPEKGSATGYVAKYISKNIDGYALDGETDDESGELLKETAPAVSAWAARWHIRQFQFIGGAPVTVYRELRRMADPETARALSVEFAAVHDAAHYGRWADYVNAQGGPFVRRDDLQVRTLYEPRTEFNQYGEETVCIKGVYDASIGAGSPILTRLTQWKIVPKRAVDLAVDVKGASAPSRSSVNNCTGSESDPPILDLTKPLSRRERRELTNRLRKKKPTTRRKFIHGTDKQNVAITKTIDEIHSDNRHHNQPGRSPAPDGRW
What is the function of this protein?
Endonuclease which induces a single-strand cut at or near ori.  May act by forming a covalent link to the 5'side of the nick.
What are the official names of this protein?
Replication gene A protein, GpA.
What is the protein family that this protein belongs to?
Belongs to the phage GPA family.
Protein: PDXS_SULIN
Sequence: MRLYELSFAQIEDFFYKLAEVKDIIKDSGLMEFLPELKKLDSTIQTGTTRVKHAFPIFQKGGVVMDITNVQQAQIAEEAGAVAVMVLDKLPYDVRKSGGVARMADPKIIGEVMNSITIPVMAKVRIGHYYEAKLLEALGVDMIDESEVLTPADEEHHINKWEFSVPFVNGARNLGEALRRTVEGASMIRTKGEAGTGNVSEAVKHMKIINSEIRSLISMSEEDRVKKAREYQVPYQLVELTAKIKRLPIVNFAAGGIATPADAALMMWLGADGLFVGSGIFKSQDPDERAKAVVLAAACWEYPEIVLEAQKMISEQKSMMGIDIKSLKPEELLQVRGL
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y2140_HAEIG
Sequence: MKLRAVVLGLATLCTSTATFAGMVSTSSNLEFLAIDGQKASKSLGKAKTFTVDDTQSHQVVVRLNEIVGSGSNQSLFESNPVIVTFQGNAEDLVISAPAIRNLDSGDKFNQMPNITVKTKSGNAISAKVDVLKQEGLFPSGNVLNDLAEYNASGAVASVSKFTATTSANSMVAAPAGNAKANKGKVVVQGENVAEQQLQYWFQQADKETQTRFLNWAKSHK
What are the official names of this protein?
UPF0319 protein CGSHiGG_02140.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: P85B_RAT
Sequence: MAGAEGFQYRAVYPFRRERPEDLELLPGDLLVVSRVALQALGVADGGERCPHNVGWMPGFNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPLDGPSESGHTLASLAEQFSPPESAPPILVKLIEAIEQAELDSEFYSRPELPAPRTDWSLSDLEQWDRTTLYDAVKGFLLALPAAVVTPEAASEAYRAMREVTGPVGLVLEPPTLPLHQALTLRFLLQHLGRVARRAPSPATAVHALASAFGPLLLRAPPPGGEGDGSEPAPDFPVLLLERLVQEHVDEQDTAPPALPPKPSKVKPAPTALANGGSTPSLQDAEWYWGDISREEVNERLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVELISHYRHESLAQYNAKLDTRLLYPVSKYQQDQVVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETILIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQDLRAQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQRKINEWLGIKNETEDQYSLMEDEDALPHHEERTWYVGKINRTQAEEMLSAKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR
What is the function of this protein?
Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3).  PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.  Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.  Indirectly regulates autophagy.  Promotes nuclear translocation of XBP1 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regulatory subunit p85-beta.
What is the protein family that this protein belongs to?
Belongs to the PI3K p85 subunit family.
Protein: ATG11_ARATH
Sequence: MSGSFTESFADDGKLLLCVAENGHSFEFQCSETTSVESVMRFVESVSGIALSDQLLLSLDMKLEPQKLLSAFGLPASDREVFVFNKAMLQSNSHPPSPEDVDLQDVADALPPASLHEHHPLDDASDPALKALPLYERQFRYHFHKGRTIYNCTVVKHENCERLTREQKVQQRAVEVATRNLEQYYRVIYQNFLEFMKRYKHQHRLHSDLLMNFGRDIEKLRSAKIHPYLQTESRKCLLDFVKEDNLKKAVENCASSHRQFENKIAQFQQMFVEVKRKVEELFACRASLSMKNLEVTVKDHERFIDEEKSIMQSLSKDVNTVKKLVDDCMSSQVSSSLRPHDAVSALGPMYEVHDKNHLPKMQACYNSISELLDFCKNKKNEMNNFVHGYMQKITYVTYIIKDAKLQFPVFREAMVRQDDLFADLKLVRGVGPAYRACLAEVVRRKASMKLYMGMAGQLAEKLAMKRETEVRKREEFLKTHGPFVPRDVLASMGLYDTPTQCDVNVAPYDTSLLNIEISDVDRYAPEFLVGLHSKIASLKSSLTMSGDSSLSAEPEEIGIDTFDKDNFDDILAASELIEIAGTSKMEVENAKLKADLASAISRICSLGPQFEYEVLDESEVENVLKNAADKTAEALQAKDEYEKHLLLMLKEKQMHCDSYEKRIRELEQRLSDEYLQGQRHNNKDVSGLNLMHEKVSEYKAEASSDVEGNKTHVSGSEPMDEVSCVSNLTSKQPCKAREGMDENMVDSSQVLSQPLDSSMLESQQNNEKGGKDSEAGEMGVFLSNSSTAESPQKSLDDNVATGRGLDAKDSGDIILELRNELMEKSNKLSEMESKLNGAMEEVSNLSRELETNQKLLEESQMNCAHLENCLHEAREEAQTHLCAADRRASQYTALRASAVKMRGLFERFRSSVCAGSGIADFADSLRTLAQALANSVNENEDDGTTEFRKCIRVLADKVSFLSKHREELLEKCQNLEATSEQTRKDLEEKKELVKTLYTKHQLGKQANKEKISFGRLEVHEIAAFVLNQAGHYEAINRNCPNYYLSSESEALFTDHLPSRPTYIVGQIVHIERQIVKLPSQLSASASPEAGKTHHLCSDQGSRTLASSSISTSTSATTTSNPYGLSSGCEYFIVTIAMLPDTAIHQQAS
What is the function of this protein?
Accessory protein involved in autophagy.  Acts as scaffold protein of the ATG1-ATG13 complex for faithful delivery of autophagic vesicles to the vacuole.  Involved in the stress-induced phosphorylation of ATG1A for turnover of ATG1-ATG13 complex and proper ATG1-ATG13 complex assembly or activity.  Required for selective mitophagy.  Required for senescence-induced breakdown of mitochondria-resident proteins and mitochondrial vesicles.  Seems not essential for ATG8-mediated autophagy.
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome.
Protein: RS21_ACIB5
Sequence: MPQVKLKEGEPVDVAIRRFKRSCEKAGVLADVRKREFYEKPTQERKRKKAAAVKRYQKKLARESVRTTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: EFG_ECOLU
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEEEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_MARSD
Sequence: MFITFEGIEGTGKTTQIKKLTAFLEESGHNVDVTLEPGGSRIGKELRKILLNMDSTDITGECELFLYLADRAQHVGQVIKPAVEAGKIIISDRFADSTIVYQGYGRGLDPKLLRELNDVAVSGNWPDLTILLDIDPEIGLKRAMTRNLQENKMQEEGRFEAESLEFHNRVREGYLTWAALNNDRIVVVNADQTPDEIFKEIKAKVVERIKGDFVTNG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MUTL_BRUAB
Sequence: MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ARLY_CLOAB
Sequence: MKLWGGRFRESESELMEEFNASLSFDKKLYEEDIEGSIAHVKMLNKCKIINNEECEEILSGLKSLYKDIRSGKLKIEGDYEDIHSFVEVNLIDRIGAVGKKLHTARSRNDQVAVDMKMYVKKSSYIIIECINKLMETIKDKAENNHFIMPGYTHMQRAQVVTFTHHMMAYYSMFNRDKKRIDNAISNLNESPLGCCALAGTTYDTDREMTSKELGFSKPVDNFLDGVSDRDYIIEVLSAFSICMMHLSRLSEELIIWSTKEFSFIQMDDKFSTGSSIMPQKKNPDAAELIRGKTGRVYGDLIAMLTIMKGIPLAYNKDMQEDKEQFFDSFDTLKMCILVMDGMIATMTVKKEAMKEAVKGGFLNATDVADYLVNKGVAFRDAHKISGELVIYCENNDKAIEELNINEFKNFCNLFDEDVYEFINYNNVIKKGNKKIM
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_AEDAE
Sequence: MASRAQNRRPAQEVDNTISYVQCDGLAAMKMVKHCHEESRSNMEVAQGALLGLVVDDRLEITNCFPFPKSSDETIDEEEYQLNMMRRLRLVNVDHFHVGWYQSADVGNFLSLPLLESQYHYQTSIEESVVVIYDTQKSARGFLTLKAYRLTPQAIAMYKEEKFTPEALRNLKVGYENLFIEIPIVIKNSALCNIMMSEMKEMVPEEEGTHFLDLGTASVLENHLRCLMDRVDELNQEANKFNKYQQTVIRQEQDKHRMLAKHAQENAARIAKGEAAIPDEEVQKLFRPLPVPSRLNPMIVSGQINTYAQHISQFCSQSLAKLYMTQALQGAKENKQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.