PharMolix/UniProtQA huggingface dataset:
Protein: UCRI_TRIEI
Sequence: MAQAEGTPDVPSMGRRQFMNLLTFGTVTGVALGALYPVVNYFIPPSSGGSGGGVTAKDALGNDIIVSEFLANHNSGERTLAQGLKGDPTYVVIEGEQTLAEYGLNAVCTHLGCVVPWNGSENKFICPCHGSQYDNTGKVVRGPAPLSLALVHANVSDDKLVFTQWEETDFRTGEKPWWV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: RECU_STAA2
Sequence: MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_CLOD6
Sequence: MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMITSRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSITTIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLVESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAILDTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKKMASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIREEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVPSDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAKPELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEKERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEKLDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAPVFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFTPEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLKEFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKGIFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNTQDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTRAKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSNLLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVNNPDSDYYGEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQNEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNPYKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVMLRGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEKCIYLFGVDEAVCY
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: PROA_DESPS
Sequence: MTLEETIVEVGVRAKAAAADLMSLATRQKDAVLSQVGELLVAEKAFLQEENEKDLAAGREKGLSDAMLDRLALTDSVIESMVKGLKEVIALPDPVGRTLGSVKRPNGLSVGRMCVPLGVIAMIYESRPNVTIDAAALCLKAGNAIILRGGSEAIHSNLALASILRRALEEAEVNPDSVQVIPMIDREAITIMLGLEDSIDLVIPRGGEGLIRFVSKNSSIPVLKHYKGVCHAYIDKDADLAKVAPIVINAKTQRPGVCNALEGILIHEDIVADVLPGLATELAELGVEMRGCSQSLPFSEHIVAASEEDWGTEFLRLCLCVKVVRSFEDAKSYIRKYGSQHTEAIITENYTTAHRFVAEVDASAVVVNASTRFNDGGELGLGAEIGISTTKLHAYGPMGLEELTTKKFVILGDGQIRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH2B1_MOUSE
Sequence: MNGAPSPEDGVFPSPPALPPPPPPSWQEFCESHARAAALDLARRFRLYLASHPQYAEPGAEAAFSGRFAELFLQHFEAEVARASGSLSPPVLAPLSPGVEIPPSHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVPSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGAVDSPSQAGPLETTSGPPVLGGNSNSNSSGGAGTVGRALANDGTSPGERWTHRFERLRLSRGGGTLKDGAGMIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRENTFVVKVEGPSEYILETSDALHVKAWVSDIQECLSPGPCPAISPRPMTLPLAPGTSFFTKDNTDSLELPCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASFSPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSTPYPPLDTPEAATGSFLFQGESEGGEGDQPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSQRQQERSTSRDPAQPSEPPPWTDPPHPGAEEASGAPEVAAATAAAAKERQEKEKAGSGGVQEELVPVAELVPMVELEEAIAPGTEAQGGAGSSGDLEVSLMVQLQQLPLGGNGEEGGHPRAINNQYSFV
What is the function of this protein?
Adapter protein for several members of the tyrosine kinase receptor family.  Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), platelet-derived growth factor (PDGF) and fibroblast growth factors (FGFs).  In growth hormone (GH) signaling, autophosphorylated ('Tyr-813') JAK2 recruits SH2B1, which in turn is phosphorylated by JAK2 on tyrosine residues.  These phosphotyrosines form potential binding sites for other signaling proteins.  GH also promotes serine/threonine phosphorylation of SH2B1 and these phosphorylated residues may serve to recruit other proteins to the GHR-JAK2-SH2B1 complexes, such as RAC1.  In leptin (LEP) signaling, binds to and potentiates the activation of JAK2 by globally enhancing downstream pathways.  In response to leptin, binds simultaneously to both, JAK2 and IRS1 or IRS2, thus mediating formation of a complex of JAK2, SH2B1 and IRS1 or IRS2.  Mediates tyrosine phosphorylation of IRS1 and IRS2, resulting in activation of the PI 3-kinase pathway.  Acts as positive regulator of NGF-mediated activation of the Akt/Forkhead pathway; prolongs NGF-induced phosphorylation of AKT1 on 'Ser-473' and AKT1 enzymatic activity.  Enhances the kinase activity of the cytokine receptor-associated tyrosine kinase JAK2 and of other receptor tyrosine kinases, such as FGFR3 and NTRK1.  For JAK2, the mechanism seems to involve dimerization of both, SH2B1 and JAK2.  Enhances RET phosphorylation and kinase activity (By similarity).  Isoforms seem to be differentially involved in IGF-I and PDGF-induced mitogenesis, according the order: isoform 3 > isoform 4 > isoform 1 > isoform 2.
What are the official names of this protein?
SH2B adapter protein 1, Pro-rich, PH and SH2 domain-containing signaling mediator, PSM, SH2 domain-containing protein 1B, SH2-B PH domain-containing signaling mediator 1.
What is the protein family that this protein belongs to?
Belongs to the SH2B adapter family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PYRF_SALEP
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLHDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQAFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DAPAT_BACFN
Sequence: MALVNEHFLKLPGSYLFSDIAKKVNTFKITHPKRDIIRLGIGDVTRPLPKACIEAMHKAVEEMTSAETFRGYGPEQGYDFLIEAIIKNDYAPRGIHLSPTEVFVNDGAKSDTGNIGDILRHDNSVGVTDPIYPVYIDSNVMCGRAGVLDTESGKWSNVTYMPCTAENHFIPAIPEKRIDIVYLCYPNNPTGTTLTKAELKKWVDYALANDTLILFDAAYEAYIREPDIPHSIYEIKGAKKCAIEFRSFSKTAGFTGVRCGYTVVPKELTAATLEGERIPLNRLWNRRQCTKFNGTSYITQRAAEAIYTPEGKEQIQETINYYMTNARIMKEGLESTGLKVYGGVNAPYLWVKTPKGTSSWRFFDQMLYEANVVGTPGVGFGPSGEGYIRLTAFGERDDCIEAMRRIKNRL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.  Can also use m-DAP instead of LL-DAP as the amino-group donor.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: RNC_SALG2
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP7_YEAS7
Sequence: MSDEDSMLLNFTTNEDTAGSSYKQAAKVTGGRWKDRRRMKMKLEGKTVSRKRKANTTGDEGIIPGRGENSIKKLHKESSYSSEEQEKYKGRNAHNTQGRTLPADSQFVSSLFTSNREITTAVNTNIHDENVAINPSNAPLKGDQFASLGVTSLLVSHLEQKMRIKKPTSIQKQAIPQIIGNAGKNDFFIHAQTGSGKTLSYLLPIISTILNMDTHVDRTSGAFALVIAPTRELASQIYHVCSTLVSCCHYLVPCLLIGGERKKSEKARLRKGCNFIIGTPGRVLDHLQNTKVIKEQLSQSLRYIVLDEGDKLMELGFDETISEIIKIVHDIPINSEKFPKLPHKLVHMLCSATLTDGVNRLRNVALKDYKLISNGTKKDSDIVTVAPDQLLQRITIVPPKLRLVTLAATLNNITKDFIASGQQSKTLRTIVFVSCSDSVEFHYDAFSGSDGHHKNLTGDSVRLLTKGNTMFPCFSDSRDPDVVIYKLHGSLSQQMRTSTLQHFARDNEATKGKHLIMFCTDVASRGLDLPHVGSVIELDPPFAVEDHLHRVGRTARAGEKGESLLFLLPGEEEKYMDYIQPYHPMGWELLKFDKEILMPAFKDVNVNRNDKFIRKDEKSSKNKDVGDKEYEWDTNATTWHLNIERRVVGDSAFKNLAVKGFISHVRAYATHISQEKKFFNVKFLHLGHLAKSFGLRERPKAMGLQSSKDGNSEKKPTKENSKNKMFRMARMAEKQIASEFNY
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP7, DEAD box protein 7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL34_UREU1
Sequence: MKRTFQPNNRKRAKVHGFRARMKTKNGRNVLARRRLKGRHSLTVSGEK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RNPH_MANSM
Sequence: MRPNNRAVNEPRPIKITRHYTKHAEGSVLVEFGDTKVICTATVEDSVPRFLKGQGQGWVTAEYGMLPRSTHSRMLREAAKGKQGGRTMEIQRLIARSLRAMVDLTALGERSITLDCDVIQADGGTRTASITGACVALTDAINALVENGTLKTSPLKGLVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLLNLAKQGCNMIFDAQRRALAADC
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: FINO_ECO57
Sequence: MAEQKRPVLTLKRKTEGETPVRSRKTIINVTTPPKWKVKKQKLAEKAAREAELAAKKAQARQALSIYLNLPTQDEAVNTLKPWWPGLFDGDTPRLLACGIRDVLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEAYAAARLDKIRRQNRIKAELQAVLDEK
What is the function of this protein?
One of the components on the FinOP fertility inhibition complex, which inhibits the expression of traJ gene, which in turn regulates the expression of some 20 transfer genes.  The transfer genes are responsible for the process, called conjugal transfer, in which DNA is transmitted from one bacterial host to another.  RNA-binding that interacts with the traJ mRNA and its antisense RNA, finP, stabilizing finP against endonucleolytic degradation and facilitating sense-antisense RNA recognition (By similarity).
What are the official names of this protein?
Fertility inhibition protein, Conjugal transfer repressor.
What is the protein family that this protein belongs to?
Belongs to the FinO family.
Protein: MPAB_PENBR
Sequence: MSLPLPPALSELARALPYSRTQWLPIFVGFLIGYPILIRALRYKRHGEMKKKFYFPTRESMAEMTDEEAFLIQKEMAQLEFPFMFLTSGQFALFRTYGIPTISHLLTKTGQFSKPETSFKRYTDTAALIGEMVENSPTSQRAFISVARTRFLHSGYQASGKILDADLLYTLALFAVQPVRFIENFEWRTLSDLELCAIGTFWKSLGDALGISSEILPSGKTGFKDGIQWLEEVDVWSQDYEAKYMVPDPKNRESADQATAMLISNRYEAPTPGWSMVFSTLLAIRKLILRYLSPPRPAALAVSNIAQKPDKDDRYHRMSWDALPFYIRPTFWNRWGPMAWISWLMGHPVPGDLGQKKGPQGDPGNDEGIKDLKDGEMSLPLVWSKYHATTND
What is the function of this protein?
ER-bound oxygenase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (By similarity).  MpaB catalyzes the oxidative cleavage the C19-C20 double bond in farnesyl-DHMP (FDHMP) to yield FDHMP-3C via a mycophenolic aldehyde intermediate (By similarity).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:21398490, PubMed:22544261) (Probable).
What are the official names of this protein?
ER-bound oxygenase mpaB, Mycophenolic acid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the mpaB oxygenase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PHL11_ARATH
Sequence: MGLIKNTVHYCCVSRDNQILYSYNGGDQTNESLAALCLEKSPPFHTWYFETIGKRRFGFLIGDGFVYFAIVDEVLKRSSVLKFLEHLRDEFKKAARENSRGSFTAMIGSINVEDQLVPVVTRLIASLERVAESSSNNELKSSNLGEQSEGSNSTKAPLLGRLSKQEKKKGKDHVIELEEHRKSNDRGNITDDSAGAGTSLEKECVSSSGRSVTQSFEWKWRRLVQIVLAIDAAICLTLFGIWLAICRGIECTRS
What is the function of this protein?
Non-SNARE longin protein involved in membrane-trafficking machinery.
What are the official names of this protein?
Phytolongin Phyl1.1.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: GDIR2_DICDI
Sequence: MINHNIISFKKFEAIFEQRPGGLELNMPIEIGSNNVDLTSKPFNIKGGSHYKVKIGYMASEPITDLICQIHTFRKSTPYGRDTQKVGDICANTNDLEFDFPKFGWEQASTQSSSMGDYTIKMYFKGNGNQDLATFFYSFNVAPDWENALPIN
What is the function of this protein?
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
What are the official names of this protein?
Putative rho GDP-dissociation inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the Rho GDI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_PROM0
Sequence: MAKVWSKRFDNALDPFIEKFNASIGFDKKLILEDLDCSIAHAKMLGKTKVLSPSETLQIINGLESIKVEYLEGKFSPSLPSEDIHYCIEHKLISLIGETGKKLHTGRSRNDQVGTDIRLWLRKEIDNIEILIADLQKSFLNLAKANIYTLIPGYTHMQRAQPLSLAHHLLAYIEMLQRDRERFKEVRGRVNISPLGAAALAGTKIKIDRHFTAAELGFEKIYKNSIDAVSDRDFCIEFVSTSALLMSHLSKISEEIILWVTDEFSFAKLTDKCATGSSLMPQKKNPDVPELIRGKTGRVYGHLQALLTMVKGVPLSYNKDFQEDKEPIFDTAETISSCITAMTILLNEGIEFNIQNLSDSVENDFSNATDLADYLVSKDVPFRTAYQVVGEIVKYCLKRKMLFKNLKIDEFKKFHPEFDEDVFVDLKPFNVVKSRNSEGGTGFAQVEKEVKNWQKKLSI
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_PASMU
Sequence: MEYRVKSTALLDIKSNIIIGLYENGELSPSAQKIDEISQGYLSKLIQSGEIKGKLGQVLVLRHVPNYSAERVFVVGAGKKGEINEKQFKQLIQDTINAVKATSAKEVISYLSDIKIKDRDLYWNIRFSVETLETSIYQFEQFKSKKSEQDVALTDVIFSAEGDVAQQAVNHAKAIALGVRAAKDVANCPPNVCNPVYLAEQANALATRSDLIKTTVLGEKDMADLGMNAYLAVSQGSVNEAQLSLIEYRNHPNPDAKPIVLVGKGLTFDAGGISLKPAEGMDEMKYDMGGAASVYGVMNAIAELKLPLNVIGVLAGCENLPDGNAYRPGDILTTMKGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDVATLTGACVVALGAHNSGLISTDDKLAKDLELAAAQSTDKAWRLPLGEEYQEQLKSNFADLANIGGRWGGAITAGAFLSNFTDKYRWAHLDIAGTAWLQGANKGATGRPVPLLVQFLINQATGK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THDH_BLAAD
Sequence: MSNISTPRISGLTEYTSQPDKSHYDSIESHFLLPDGTPDYLKLILTSKVYDVCNETPVTPAVNLSSKLGANIFLKREDLQPVFSFKLRGAYNMMAHLPQETRWKGVIACSAGNHAQGVAYSAKHLNIPATIVMPVVTPAIKYKNVDRLGAKVVLHGNDFDAAKAECNRLSEKHGLTNIPLFDNPYVIAGQGTIGVELLRQIDVESLKAIFVCIGGGGLIAGVGAYIKRIAPQVKIIGVETYDANAMRQSLQKGERITLSEVGLFADGAAVKILGEETFRLCQQVVDEIVLVSTDEICAAIKDVFTETRSIVEPAGALSVAGLVKYVESHPEIDHSASGYTAILSGANMDFDRLRFVSERAKLGEGSEVFIVATIPEKPGSFGKLIDLVHPRAVTEFSYRYSNGELEKSDGKAHVYISFSVDNAKAEVPRILDDFKGAGFDAIDISHNEFPKSHPRYLVGANQPVTNERVFRFEFPERPGALVKFLHGVKSKWNITLFHYRNQGSDIAKVLAGISVPSHESDQFQQFLDNLEYPYAEETDNVVYKLFSQGD
What are the official names of this protein?
Threonine dehydratase, mitochondrial, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTSH_TROWT
Sequence: MSKITKSPVLYIVLLVVGVWVAVNLFLTNAYQSIRTEEGLELIKSDSLVSVRIVDRDQRVDLELATPYKNHGTKVQFNYVSQRATEIVNAVNKAKIKDGFTDEVPAPSVWGSIISMLLPIAAIGLFLWFMAGPQAAGGRGIAQFSRMRSRLVSKEMPKVRFTDVAGADEAVEELQEIKDFLSDPDKYRKLGARIPKGVLLFGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKQNSPSIIFIDEIDAVGRRRGSGFGGGHDEREQTLNQLLVEMDGFDVKTNIILIAATNRSDVLDSALLRPGRFDRHVAIDAPNLQGRLKILQVHARTKPVSKSVDLEVLARKTPGFTGADLANVLNEAALLTARSNAQIIDDRALDEAVDRVMAGPQRRSRVMTDHEKLVTAYHEAGHALTAAAMRYSDPVTKVTILPRSRALGYTMVMPVQDRYSVTRNELLDKLAYAMGGRAAEELVFHDPTTGASNDIEKATSIARKMVTEFGLSKDLGAVKFGNAHNETLMGVGQMTARDYSEVTAERIDVQVRALIQNAHDEAWEVISNNRNLLDDLALNLLEKETLNQDEIAEIFKGVRKLPERHVWQSAPNREPSNKPPVKYSAMGPDSEVTAKSPKRTSNRRRLPSARRPRKDSETQE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: DPO4_NEIMF
Sequence: MSSRKIIHIDMDAFYASVELREQPHLKGRPVVVAWEGARSVICAASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAVFRRYTDLIEPLSLDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPNGQFVLPPHKVMAFLETLPLGKIPGVGKVTLKKMQSLGMRTAGDLRRFERGELLNHFGRYGYRLYDLVRGTDERPVKAERERLQISTEITLPEDLPLEQAAGHLPHLAEDLWRQITRKNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCAALLQAAQMLIARVPPQTEDAFRLIGIGVGHLVPKNQQQDLWA
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_SACD2
Sequence: MSEEIHLSVDAMGGDFGPRLCVEAAASFIAKHSNVRITLVGDKAAVSSCIPPQADLSRLHVLHADQVVDMADKPSHALRHKKNSSMWRALQLVADGEAQACVSGGNTGALMAIGCHLLKTIAGIDRPAIAKQIPTARGSSVLLDLGANLECSPQQLFQFGLMGQGLARVYGKSEPTVALLNVGSELTKGNDIIQDTAQLMGDCADMHFRGFVEGDSLYSGEVDVVVCDGFIGNVALKVSEGVAKFVFGDLRSRIGRGVRSRLLAWLAKPVLKPWAEQFRPAKYNGAALLGLKGVVIKSHGGADAEGFEQALYVALEQASAGIPLKIQASLAAMLGAGLETK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RL34_MYCPA
Sequence: MAKGKRTFQPNNRRRARVHGFRLRMRTRAGRAIVSGRRRKGRRALSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.