PharMolix/UniProtQA huggingface dataset:
Protein: MNMC_BORA1
Sequence: MSSAYQPLTPALTEVNEAGHLASRQYGDVYNSPADAYGQAVDVFLHGNDLPQRWRGRRHFTVCETGFGLGTNFLALWRAWREDPGRCGRLHMLSIEGHPLTREAYEAVLDTQVPEPLRAGARELLAQWPKLLPGLHRLEFEHGAVTLTLALGDIGQVAPRLSACVDAFFLDGFAPSKNPAMWDTYVLRRLLRLGAADATLATWTSAGFVRRGLQEAGFDIQRLTGARGKRHITVGRRSAWAGKHAPRRTDAPDAPVLVVGAGLAGAGMAQALALRGLSVRVIAESAQPHGGHLAAALTPLVARDDNARARLARAGSQRAWHRWQGLDAVRKVGALQLERDAGRSAALADTLAALHFPRDWVRWVESDEAEQLAGLPVARGGLYFADGLLVRPQPLIDALLAWPGIERVRGRVSRLVQCSAGQWQALDALGQVLGEARQVVLANAAGTPLVLEASGLLGPLPRVAQMHALAGEVSHVPAAALGGGPHCMIGGEGYVLPAVDGWCVVGSTYAPGVAQSEVSLAGQQRNLEKAAGLLGAPLDAVAGPLPGWAGWRAVMPGRLPVLGELPGVSGVWLASAYGSRGLSWSALAGDVIAARLCGEPLPLETDLLASVGPR
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEP8B_DANRE
Sequence: MAATEVNTYPTEEMRSLSLSGHVGFDSLPDQLVSKSVSQGFSFNILCVGETGIGKSTLMNTLFNTTFENEEASHFHNGVHLRPRTYSLQESNVDLQLTIVDTVGFGDQVNKEESYKPIVDYIDAQFENFLEEELKIKRSLYNYHDSRIHICLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTVSKSELQKFKIKIMSELVSNGVQIYQFPTDDEAVAEINSSMNAHLPFAVIGSSEEVKIGNKMVRARQYPWGVVQVENESHCDFVKLREMLIRVNMLDLREQTHARHYELYRRCKLEEMGFKDTDADSEPFSLQETYVAKRREFIVELQMKEEQMRQMFVNKVKETEAELKEKERELHERFEMLKRTHQEEKRSLEEMRRDFEEEMNTFNRRKVAAETLQSLQGSTGLKKDKEKKT
What are the official names of this protein?
Septin-8-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Protein: MUTL_LACLM
Sequence: MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSKIKDSADLFRIRTLGFRGEALPSIASVSQMTIETSNAQEEAGTKLIAKGGTIETLEPLAKRLGTKISVANLFYNTPARLKYIKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMREINGSDLDFELTGYVSLPELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAVLSIKIDPKLADVNVHPTKQEVRLSKERELMTLISKAIDETLSEGVLIPEALENLQGRAKEKGTVSVQTELPLQNNPLYYDNVRQDFFVREEAIFEINKNDNSDSLTEQNSTDYTVNQPETGSVSEKITDRTVESSNEFTDRTPKNSVSNFGVDFDNIEKLSQQSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHAAQERIKYEYWKDKIGEVSMEQQILLAPYLFTLPKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSINEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLRELSTCKNPYSCAHGRPTIVHFSGDDIQKMFRRIQETHRSKAASWKDFE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CBIN_METTM
Sequence: MDKRHTIMLIAVAVIAIAPLVIYSGLGEDQGYFGGADDSASKAISETGYKPWFQPIWEPPSGEIESLLFALQAAIGALIIGYVFGYYRGRGESPE
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPP_COXB2
Sequence: MSVLVPMVVEQTSRGERAYDIYSRLLKDRVIFLVGQVEDHMANLAIAQMLFLESENPNKDINLYINSPGGAVTSAMAIYDTMQFVKPDVRTLCIGQAASAGALLLAGGAKGKRHCLPHSSVMIHQVLGGYQGQGTDIQIHAKQTQRVSDQLNQILAKHTGKDIERVEKDTNRDYFLTPEEAVEYGLIDSIFTERP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_SHIBS
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSDQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: NCBP1_DROWI
Sequence: MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGERSTSSVESNLEGLVSVLEADLGTFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKLCRWDAARYSLRFLADLVNCHVISATSLLQLLDTMIDVSNEDTVPQVRRDWFVFAVLSTLPWVGRDLYEKKESALESLLLRIEVYLNKRSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEKHIPRPYLVFDSILCEALQHNLPQIIPPPHHDAFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETHHYERKDCAAQLLNFPFKHKIPLEYCIVEVIFAELFHMPTPRYLDICYGSILIELCKLQPGTLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLEAEHPRPKFIQEVLQKCLRLSYHQRITEMMPTTYAKLIPLTPVPNYKYANEEAANLPGTTVAHQLVVAIRQKCTPEEVVNILKEIPSSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHAVFRALAETEEAQICILHNIFELWSSHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKMYLWEILHLTIKKMNKHVIKLNTELSDAKDKLSKADSSSSDSDEDTPHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of Cbp20 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BACD_BACIU
Sequence: MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHAALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHDKPEEEVVEEIVKVAGMFAVDAITTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRAAFNRAGVKSIKNKRVTTLEDFRAALQEIGTPLILKPTYLASSIGVTLIKEMETAEAEFNRVNEYLKSINVPKAVTFEAPFIAEEFLQGEYDDWYETSGYSDYISIEGIMADGEYFPVAIHDKTPQIGFTETSHITPSILDDDAKRKIVEAAKKANEGLGLENCATHTEIKLMKNREAGLIESAARFAGWNMIPNIKKVFGVDMAQLLLDVLCFGKEADLPKGLLEQEPCYVADCHLYPQHFKENGQLPETAVDFVIESIDIPDGVLKGDTEIVSFSAAEAGTSVDLRLFEAFNSIAAFELKGSNSGDVAESIKQIQQQAKLTAKYALPV
What is the function of this protein?
Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase.  Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP.  In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide).
What are the official names of this protein?
Alanine--anticapsin ligase, ATP-dependent dipeptide ligase, Bacilysin synthetase, L-Ala-L-amino acid dipeptide ligase, L-alanine--L-anticapsin ligase, L-amino acid ligase, Lal.
Protein: RS111_ARATH
Sequence: MAEQTEKAFLKQPKVFLSSKKSGKGKRPGKGGNRFWKNIGLGFKTPREAIDGAYVDKKCPFTGTVSIRGRILAGTCHSAKMQRTIIVRRDYLHFVKKYQRYEKRHSNIPAHVSPCFRVKEGDHIIIGQCRPLSKTVRFNVLKVIPAGSSSSFGKKAFTGM
What are the official names of this protein?
40S ribosomal protein S11-1, Protein EMBRYO DEFECTIVE 1080.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_YERPE
Sequence: MTDIFANPDKTLDALGLRCPEPVMMVRKTVRHMEEGQTLLIIADDPATTRDIPGFCRFMDHQLLAQDTEQTPYRYLVRKGITAG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STAAC
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_PSELT
Sequence: MKIRVGILGATGYTGLELLRMLKNHPQVKITYLSSNNFSGQSMKDIYPFAEIDILLSKIDVKEIKANCDVVFTALPAGISYDIVKSLRDENLKIIDLGADLRFDDPSLYEKWYGRTLQDYGLIKRVYGLPELYRSEIKESRFIGNPGCYPTSILLATAPILKRKLLVNGEIIVDSKSGVSGAGKKEELAYSFCEIDGSLKPYSVINHKHVPEIQEQMKKIYHSEVTVIFAPHLVPMVRGILSTIYLKTRLSADELYGLYSEFYRDEYFVHVLKPAIYPSTKWSYGSNHVFISMKKDERTDTAVLISVLDNLVKGASGQAIQNMNILFSLREDTGLTFTVYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_EDWI9
Sequence: MVRTMLQGKLHRVKVTQSDLNYEGSCAIDQDFLNAAGILQYEAIDIYNVDNGQRFSTYAIAAEPGSKIISVNGAAARCACVGDTLIICSYVQIPDEQARTHHPRVVYFEGANQMKRLAKSVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATY_ECOLU
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPVQAREFAEATGIDSLAVAIGTAHGMYASAPVLDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: Y484_METBF
Sequence: MTDLEIYRKRLERIEELLSELSEYSGRGAIIIVEGKRDVLSLKRLGIEGNFELATHQSLFNFSEKIARLGNEVVILTDWDRRGDILAIKLSGYFQSFGLKPELEIRNKLRLISQKEIKDVESLYTYVSKLRLKTGYCSKRDFQ
What are the official names of this protein?
UPF0292 protein Mbar_A0484.
What is the protein family that this protein belongs to?
Belongs to the UPF0292 family.
Protein: RPC10_SCHPO
Sequence: MQFCPTCGNHLIVAVDEEGRNAFDCRTCPYHFPISTFLYSRHEFAQKEVDDVLGGEEAFESNQQTEVTCENTKCDNNRAYFFQLQIRSADEPMSTFYRCTKCKFQWREN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC10, RNA polymerase III subunit C10, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III subunit C11.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL44_KLULA
Sequence: MVNVPKTRKTYCKGKECRKHAQHKVTQYKAGKASLYAQGKRRYDRKQSGFGGQTKQIFHKKAKTTKKVVLRLECMSCKTKTQLALKRCKHFELGGEKKQKGQALQF
What are the official names of this protein?
60S ribosomal protein L44, 60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: ENV_HV1ND
Sequence: MRAREKERNCQNLWKWGIMLLGMLMTCSAAEDLWVTVYYGVPIWKEATTTLFCASDAKAYKKEAHNIWATHACVPTDPNPQEIELENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDELRNSKGNGKVEEEEKRKNCSFNVRDKREQVYALFYKLDIVPIDNNNRTNSTNYRLINCDTSTITQACPKISFEPIPIHFCAPAGFAILKCRDKKFNGTGPCSNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNVKTIIVQLNASIVINCTRPYKYTRQRTSIGLRQSLYTITGKKKKTGYIGQAHCKISRAEWNKALQQVATKLGNLLNKTTITFKPSSGGDPEITSHMLNCGGDFFYCNTSRLFNSTWNQTNSTGFNNGTVTLPCRIKQIVNLWQRVGKAMYAPPIEGLIKCSSNITGLLLTRDGGANNSSHETIRPGGGDMRDNWRSELYKYKVVKIEPIGVAPTKARRRVVEREKRAIGLGAVFLGFLGAAGSTMGAASVTLTVQARQLMSGIVHQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGRHICTTNVPWNSSWSNRSLDEIWQNMTWMEWEREIDNYTGLIYSLIEESQIQQEKNEKELLELDKWASLWNWFSITKWLWYIKLFIMIVGGLIGLRIVFAVLSVVNRVRQGYSPLSFQTLLPVPRGPDRPEEIEEEGGERGRDRSIRLVNGLFALFWDDLRNLCLFSYHRLRDSILIAARIVELLGRRGWEALKYLWNLLQYWSQELRNSASSLLDTIAIAVAERTDRVIEVVQRACRAILNVPRRIRQGLERLLL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: THIE_HAEIN
Sequence: MKNIQKILPLYFVAGTQDCRHLGENLSENLLFVLKQALEGGITCFQFRDKGKFSLEHTPSAQKALAINCRDLCREYGVPFIVDDNVDLALEIEADGIHVGQSDMPVQEIRAKTDKPLIIGWSVNRLDEAKIGENLAEIDYFGIGPIFPTQSKENPKPTLGMAFIQTLRNAGITKPLVAIGGVKLAHVKTLREFGADGVAVITAITHADNVQAATKALREASDEYAK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RIBL_METB6
Sequence: MTARRVVATGTFDILHPGHVYYLTESRKLGDELWVIVARDENVKHKPRPILPEAQRLAMVSALRPVDHAILGDHTDMFCPIDDIRPAVITIGFNQYFDEEKLKGQLAERNLPAEVVRIGKYEDGDLASSRMIVQRIVEARGSGDQRIG
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: TIG_RHIEC
Sequence: MQVIETLAEGLKREIKVVIPAKDMEDKMNERLADVKDKIRINGFRPGKVPAAHLKKVYGKSIMADLVNEIVREQPAAILSSRGEKSATQPEIAMTEDKDEADKILTAQQDFEFTLSYEVLPPIELKSVKGIKVTREVIDISDDEVNEQVLKVAESARSYESKTGKAANGDRITMDYVGKVDDEAFEGGTDQGAELVIGSGRFIPGFEDQLVGVKAGEEKTITVTFPADYPAKNLAGKEATFDVTVKDVAAPGAVEINDELASKLGIESADRLKEIVRGQIESQYGSLTRQKLKRQILDQLDEMYKFDTPASLVDAEYNGIWSQVNNDLAQSGKTFEDEDTTEEKAREEYKTLAERRVRLGLVLSEIGEKAGVEVTEDEMQRAIYDQLRQYPGQEKQILEFFRSQPGAAASIRAPIFEEKVIDHLLTEIDVTDKKVTKEELLAEDEGEAKAETKKAAPKKKAAAKSEAAEAGEGEEAAPKKKAAPKKKASEDSAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TRMB_CORGL
Sequence: MSISDNSRDQLGELPAGRPLQSDFDNDLDYPRLGSVTFRRGTLTENQQTMWDEKWPELGRVLEDELIDVDAWFGREGAKTIVEIGSGTGTSTAAMAPLEADTNIVAVELYKPGLAKLMGSVVRGEIDNVRMVRGDGIEVLNRMFADGSLDGIRVYFPDPWPKARHNKRRIIQSGPLNLFAKKLKPGGVLHVATDHADYAEWINELVEVEPLLEYKGWPWEECPQLTDRQVITKFEGKGLEKDHVINEYLWQKVQN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: AROC_ALIFM
Sequence: MAGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRREADEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQMGDVSIDSVDWNEIENNAFFCPDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFARLDADVAHALMGINAVKGVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITVPGETITRSGEKTELITKGRHDPCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CYSJ_ALIF1
Sequence: MLLKELSALASPLNDQQIGQLQQAASELSPQQLAWVSGYFWGISQTSGATQPINQAAAAVSSQPAGKLSIIFASQTGNAKGVAEALKEEAAAAGIAVELFDASDYKGKHLAKETHVIIVASTNGEGEAPDNAIELHEFLQSKKAPKLDNLHYGVIGLGDSSYEFFCQTGKDFDAFLSKQGATPFIERVDLDVDYEAPAAEWRKQALDKVKEALASEAQSAQVVQLPVGQAAHTSQYSKQNPYTATLLTSQKITGRDSGKDVRHIEIDLDGSGLTYQPGDALGVWFENSPELASAILKQVGLTGDEAVEVDGDSISLQKALVEKYEITSANPQLVTQYAELSGSKKLEKLAADKDKLRQYSGNTQVIDVLSEKKAKLTAEQLVGLLRRLTPRLYSIASSQSEVDEEVHLTVGVVEYLQGDETRFGGASSFLSHRLEEGDDVKVFVEHNNNFKLPQDDNAPVIMIGPGTGIAPFRSFVQERDNRDAEGKNWLFFGDRIFTQDFLYQVEWQKYLKSGIVNQLDVAFSRDQQEKVYVQHRILEHAAQVWQWLQDGAYIYVCGDATRMAKDVHEALICVVEQHGQKTREEAEQFVNELRKAKRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: VPC30_MYCTO
Sequence: MVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARFGEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKGRHRAGLNYGDCFSYGLAKISGQPLLFKGEDFQHTDIATVALP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB30 (By similarity).
What are the official names of this protein?
Ribonuclease VapC30, RNase VapC30, Toxin VapC30.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: YTJA_ECO5E
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.