PharMolix/UniProtQA huggingface dataset:
Protein: DHG_ECOLI
Sequence: MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
What is the function of this protein?
GDH is probably involved in energy conservation rather than in sugar metabolism.
What are the official names of this protein?
Quinoprotein glucose dehydrogenase, Glucose dehydrogenase [pyrroloquinoline-quinone].
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Periplasmic side.
Protein: EFTU_GLOVI
Sequence: MARAKFERNKPHVNIGTIGHVDHGKTTLTAAITMTLAALGRAKAKKYDEIDQAPEEKARGITINTAHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPNIVVFLNKKDQLDDPELLELVELEVRELLSKYDFPGDDVPIVAGSALMALEKMASEPKLIRGKDDWVDCIYSLMDAVDAYIPTPERAIDKPFLMAVEDVFSITGRGTVATGRIERGKVKVGETIELVGIRGTRSTTVTGLEMFQKSLDEGLAGDNIGVLLRGIKKEDVERGMVLAKPGSITPHTQFEGEVYILSKEEGGRHTPFFAGYRPQFYVRTTDVTGTIVTFTDDEGKSAEMVMPGDRIKMTVELINPIAIEDGMRFAIREGGRTVGAGVVSKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PM2PB_HUMAN
Sequence: MEKLSAASGYSDVTDSKAMGPLAVGCLTKCSHAFHLLCLLAMYCNGNKGPEHPNPGKPFTARGFPASATFQTTPGPQASRGFQNPETLADIPASPQLLTDGHYMTLPVSPDQLPCDDPMAGSGGAPVLRVGHDHGCHQQPRICNAPLPGPGPYRTEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKELVENSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLMMSPFLPATSRRRLGLDWCLITMGKSSRRPPTPTPEGPQSA
What are the official names of this protein?
Putative postmeiotic segregation increased 2-like protein 11, PMS2-related protein 6, Putative postmeiotic segregation increased 2 pseudogene 11.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MNMA_RICRS
Sequence: MINLGAKQSTIVVAMSGGVDSSAVAAMLNEQGHNVIGITLQLYDHGMAVGKKNACCAGQDIYDAKMVANKLGIPHYVLDYESKFKESVIDNFVDSYLQGETPLPCVQCNKSVKFRDLIKTARELGADKLATGHYVRKINGDNGAELHTGLDPAKDQSYFLFTTTKEQLEYLRFPLGGLTKGETRKLASKFGLEVADKPDSQDICFIPDGNYKSVINKIRPNSSESGKIIHVNGFELGEHSGIINYTIGQRRGLGIAYNEPLYVVKIDPKDNIVYVGPESALNVQEFIIRDVNWLADEIKDNEKLEVAVKIRSTRPPRLAEISKLGDDKMKVKFLCKEKAVAPGQACVIYAGARVLGGGWITREIR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXD4_HUMAN
Sequence: MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPAPPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGGEGTSPVFLVSPTPSSLAESAGPS
What are the official names of this protein?
Forkhead box protein D4, Forkhead-related protein FKHL9, Forkhead-related transcription factor 5, FREAC-5, Myeloid factor-alpha.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLN5_SHEEP
Sequence: MAQAGGAGAGAWGRRGAGAGAGPERAPWRWAPALLWLAAATAAAAAAGDPSRRQWPVPYKRFSFRPEPDPYCQAKYTFCPTGSPIPVMKDDDVIEVFRLQAPVWEFKYGDLLGHLKIMHDAIGFRSTLTEKNYTMEWYELFQLGNCTFPHLRPEMNAPFWCNQGAACFFEGIDDNHWKENGTLVLVATISGGMFNKMAKWVKQDNETGIYYETWTVQASPKKEAEKWFESYDCSKFVLRTYEKLAELGADFKKIETNYTRIFLYSGEPTYLGNETSVFGPTGNKTLALAIKKFYYPFKPHLSTKEFLLSLLQIFDAVVIHREFYLFYNFEYWFLPMKSPFIKITYEEIPLPNRKNRTLSGL
What is the function of this protein?
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane.  Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane.
What are the official names of this protein?
Ceroid-lipofuscinosis neuronal protein 5, Protein CLN5.
What is the protein family that this protein belongs to?
Belongs to the CLN5 family.
What are the subcellular locations of this protein?
[Ceroid-lipofuscinosis neuronal protein 5, secreted form]: Lysosome. SUBCELLULAR LOCATION: [Ceroid-lipofuscinosis neuronal protein 5]: Membrane; Single-pass type II membrane protein. Note=An amphipathic anchor region facilitates its association with the membrane.
Protein: CYSO_MYCTO
Sequence: MNVTVSIPTILRPHTGGQKSVSASGDTLGAVISDLEANYSGISERLMDPSSPGKLHRFVNIYVNDEDVRFSGGLATAIADGDSVTILPAVAGG
What is the function of this protein?
In its thiocarboxylated form (CysO-COSH), is the sulfur donor in the CysM-dependent cysteine biosynthetic pathway.  May be of particular importance for cysteine biosynthesis in the persistent phase of M. tuberculosis (By similarity).
What are the official names of this protein?
Sulfur carrier protein CysO, 9.5 kDa culture filtrate antigen cfp10A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein CysO family.
Protein: RS4_BUCA5
Sequence: MAKYLGPKLKLSRREGTDLFLKSGLRSIESKCKLEQPPGQHGIRKPRLSDYAIQLREKQKVRRLYGVLERQFKIYYKLAASLKGNTGANLLQLLESRLDNVVYRMGFGCTRSESRQLINHKSIMVNNKVVNIASYQVSPNDQISIRNKSKNQSRIKAALELVEQREKPIWLEVNSTKMEGIFKRFPERSDLSAEINEYLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y1314_ARCFU
Sequence: MDVIVGGGKYGVEAARFLEKRSRDYVIIDRNPECLAMRELDLVRVDSIEEVKEGRYFLKGGIEILPSLLKFKPEYIFPTAPLHVAAEALRLKFDLKPWNEVLDCIIGNLPARVVVSAGRGSVVVSYNRDADCLEKCSAPDICPVTKIKKPCPMHDLVKFAYPDAFVLISRQLEPGLGAISGEELAKLMKQAEKREKIVVATACRCHGVITALKRA
What are the official names of this protein?
Uncharacterized protein AF_1314.
Protein: TATA_POLSJ
Sequence: MGSFSIWHWLIVLLIVVMVFGTKKLKNMGSDLGSAVKGFKDGMKDGGQSAAATDDKPAAPAGQVTNAQASDKTTIDVEARQKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AAEX_YERPN
Sequence: MSLLPVMVIFGLSFPPIFLELLISLALFFVVRRILQPTGIYEFVWHPALFNTALYCCLFYLTSRLFS
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RFX6_AILME
Sequence: MAKVPVLEDAFLPAQPSPQVSPEAQEECCVQLLGKGLLLYPEERVYLAAEAQPGGARGSAERGEHPELPVGVKSEMHLSNGNFSSEEEDGESHDSKTKAADLHLSQKKTITQMMKDKKKQTQLTLQWLEENYIVCEGVCLPRCILYAHYLDFCRKEKLEPACAATFGKTIRQKFPLLTTRRLGTRGHSKYHYYGIGIKESSAYYHSVYSGKGLTRFSGSKLKNEGGFTRKYSLSSKTGTLLPEFPSAQHLVYQGCISKDKVDTLIMMYKTHCQCILDNAINGNFEEIQHFLLHFWQGMPDHLLPLLENPVIIDIFCVCDSILYKVLTDVLIPATMQEMPESLLADIRNFAKNWEQWVVSSLENLPEALTDKKIPIVRRFVSSLKRQTSFLHLAQIARPALFDQHVVNSMVSDIEKVDLNSIGSQALLTISGSTDTESDIYTEHDSITVFQELKDLLKKNATVEAFIEWLDTVVEQRVIKTSKQNGRSLKKRAQDFLLKWSFFGARVMHNLTLNNASSFGSFHLIRMLLDEYILLAMETQFNNDKEQELQNLLDKYMKNSDASKAAFTASPSSCFLANRNKGSTASSDTVKNESHVETAYLPLSSSHPGGFPSALHPFPAGNTDTMPLTGQMELSQSTGHLMTPPISPAMASRGSVINQGPMAGRPPSVGPVLSAPSHCSTFPESIYPTHPQTNQDFYGTNSNYQTVFRAQPHPPSGLYPHRPEHGRCMAWSEQQLSRDFFSGSCAGSPYNSRPPSSYGPSSHSQDSHSMQFLNTGSFNFLSSTGAASCQGATLPPSSPNGYYGSSINYPESHRLGSMVNQHVSVISSVRSLPPYSDIHDPLNILDDSSRKQTSSFYADTSPSVACRTPVVASSLQTSIPSSSSQCMYGTSNQYPAQETLDSHGANSREMVSSLPPINTVFMGTAAGGT
What is the function of this protein?
Transcription factor required to direct islet cell differentiation during endocrine pancreas development.  Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin.  Not required for pancreatic PP (polypeptide-producing) cells differentiation.  Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice.  Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.  Involved in glucose-stimulated insulin secretion by promoting insulin and L-type calcium channel gene transcription.
What are the official names of this protein?
DNA-binding protein RFX6, Regulatory factor X 6.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPTD_METJA
Sequence: MRVEETEVFKKYFKNLTDRERAVFEGGITLGALFHQFVGTPVSKYNKESLERAIEEAMKNQPCVYDIKVKIRNVGEKYVSLDGKMLDVDLKIKINKTVAHLKLEYIPEIDYPLMYVKKFEE
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin aldolase.
What is the protein family that this protein belongs to?
Belongs to the archaeal dihydroneopterin aldolase family.
Protein: ISPH_METCA
Sequence: MEIILANPRGFCAGVDRAIEIVDRAIEVFGAPIYVRHEVVHNRYVVDGLRERGAVFVEELSEVPENSTVIFSAHGVSKQIQEEARERGLQVFDATCPLVTKVHIEVHQHASEGREIVFIGHAGHPEVEGTMGQYDNPAGGIYLVESPEDVEMLQVKNPDNLAYVTQTTLSIDDTGAVVEALKMRFPKILGPRKDDICYATQNRQDAVKKLAAQCDTILVVGSPNSSNSNRLREIADKLGRKAFLIDNAAQLTRDMVAGAQRIGVTAGASAPEILVQQVIAQLKEWGGRTATETQGIEEKVVFSLPKELRRLNA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RSTR_VIBCL
Sequence: MFSSKIRDLRVERDLNQEEVANGIGVGKNTYLAYEKGTQSPKLETVEKLAKFYGVPIAELVSDSETNIDEKLKSKIRMIESLDEPEKESLFILMEALLMRSKSREIQKEFR
What is the function of this protein?
Transcriptional repressor of the integrated CTXPhi phage gene rstA2.
What are the official names of this protein?
Cryptic phage CTXphi transcriptional repressor RstR.
Protein: RLMG_VIBCH
Sequence: MKTELTLLEQTLTLHRFPKRNNETLQAWDAGDEYLIQHVEQLALPESSHIVIINDHFGTLSCWFSQKHKVSMMSDSYIAHQATQANLQQNQRPPVQLLTTLDPVPNDASVVLLQLPKSNRHLVWILSQLRKALSPNIPIIAVNKAKEIHTSTLNLFEKHLGPTTTSLAWKKHRLVFSSATVNPANEVNPECGWSIEPYAITLTNLPNVYSGESLDLGSRFILEHLPADPTLEDFIDLGCGNGVLSVRLGQLNPQAKITCVDESFMAIASAQKNLHDNLGKRDIHCIANNCLDGFPAHSSSMIVCNPPFHQQQTITDHIAWQMFCDSKHVLKKGGKLWVIGNRHLGYDVKLARLFGKSHVRVIANNSKFVILQAIKS
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_XANC5
Sequence: MTEGEGRIQLEPSWKARVGDWLLRPQMQELSAFLRQRKAAGARVFPPGPQIFAAFDATPFEQVKVVILGQDPYHGEGQAHGLCFSVLPGVPVPPSLLNIYKEIQDDLGIARPDHGYLMPWARQGVLLLNAVLTVEQGRAGAHQNKGWEGFTDHVVDTLNREREGLVFLLWGSYAQSKGKVIDQARHRVLKAPHPSPLSAHRGFLGCRHFSKTNDHLRRRGLSPIDWSLPPRSALDTTSTGA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_MONDO
Sequence: MARYRRRSRSRSRSRYGRRRRRSRSRRRRSRRRRRRRGRRGRGYHRRSPHRRRRRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NU4M_TRICN
Sequence: PIAGSMVLAAILLKLGGYGIIRIMQIMPMTKTDMFLPFLVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMATTWWLLTNLMNIATPPTMNFTSELLIMSTLFNWCPTTIILLGMSMLITASYSLHMFLSTQMGYPLLNNQTEPTHTREHLLMILHIVPLMMISMKPELVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: IDH_SPHYA
Sequence: MAKIKVKNPVVEIDGDEMTRIIWEWIRERLILPYLDVDLKYYDLSVEKRDETSDQITIDAANAIKEYGVGVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGVVFREPIVIKNVPRLVPGWTDPIVVGRHAFGDQYKATDFKVPGAGTLTMKWVGTNGEELEYEVFEFPSAGVAMGMYNLDESIRDFAKASFNYGLNRGWPVYLSTKNTILKAYDGRFKDLFQEVFDAEFADKFKAAGIVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDGKTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDDTPDVVKFAETLEQVCIKTVEGGAMTKDLALLIGPDQAWMTTEQFFEAIRVNLEAEMAKWA
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: QUEE_SHIFL
Sequence: MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: TM209_XENLA
Sequence: MKAEEQRTAMSFIDTTIKMRKEANAKKVVLAWGLLNVSLAGMIYTEMTGKMISTYYNIAYWPLWYIELALASLFSLNALFDFWRYFKYTMASPNITLSPSQQKLVGVPYSMAQSSPQPDLITNKVPVSTPSPSMQGQNVLSYSPSRSPSSSPKFLSTCISGYSPQIQAMLPNSGSPFTSVVSYSSNSFPKITSYSPSPSSPQYLSNLGPVENGGLRSRYRSSPSAYSSPTDKEDYMTDLKLLDTFLRSEEEKQHRAQLGPDASSTSTSPTFWNYSRSVGDYAHTLRKFQYQLACRSQAPSAHKDEADLGSKHAAEEVWAKVIMNRPLQDHMDAWTAKFRNWINETILVPLVYEMDSVKTQMRRLGCPDLQIGESSITSLKQAALVKAPLIPTLHIIVQYLDITPNQEYLYERLKELSHGGCMSSFRWNSGGDFKGRKWDTDLPTDSAIIMHIFCTYLDSRLPPHPKYPDGKTFTSQHFVQAPDKPDISNENVFCIHQSSINPPYYELVYQKHIYSLPKGRNNLFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGDL
What are the official names of this protein?
Transmembrane protein 209.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VGRG2_AERHY
Sequence: MADSTGLQFTVKVGALPENTFVVAEFALDEALNRPFNLRLELASAQPDIDFGAVLDQPCELLVWYNGELQRRVCGVVSDFAQGDSGFRRTRYQLMVQPALWRLSLRQNSRIFQAQKPDEILSILLQEHGITDYAFALKNEHAKREYCVQYRETGLDFVNRLAAEEGMFYFHEFEVGKHRIVFADDSAALTAGPELFFNLGNRSLEQGPYVRQFHYREAVRPSDVELKDYSFKTPAYGLSHKKVGAELTHQRDTYQHFDFPGRYKEDPSGKAFAQHRLDALRNDAVAGSGKSNSSALQPGQTFSLTEHPNDSLNTDWQIVRIQHTGLQSQALEEEGGSGPTVYHNEFGVVKASTTWRARIGSPEAPHKPMVDGPQIAVVVGPEGEEIYCDEHGRVKLQFPWDRYGSSNDQSSCWVRVSQGWAGGQYGMMAIPRIGHEVIVSFLEGDPDQPIVTGRTYHATNRPPYELPANKTRTVLRTETHQGEGFNELRFEDQAGKEEIYIHGQKDLNVLIENDAAWHIKHDQHTDIDNERVTRIKANDHLTVEGEKRDQIKADYSLTVDASLHQKLGQSLLVEAGSEVHHKAGMKIVMEAGAELTLKVGGSFVKIDPSGVTLSGGSIKMNSGGSPGSGSGWAGQMPIQPGAVEVVAPPPPMDPARQIATLKSAEPVCEICEQLARQEGGG
What is the function of this protein?
Part of the type VI secretion system specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection.  Plays an essential role in bacterial mobility and biofilm formation.
What are the official names of this protein?
Type VI secretion system spike protein VgrG2.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
Protein: YAP1A_XENLA
Sequence: MEPGSQQQPSAPAQQPPPVGHQVVHVRTDSETDLEALFNAVMNPKNANLPQTLPMRMRKLPDSFFKQPQPEAKSHSRQASTDGGSAGALTPQHVRAHSSPASLQLAAVSPGALSPQGVVTGLAPPSAPHLRQSSYEIPDDVPLPPGWEMAKTPSGQRYFLNHIDQTTTWQDPRKAMLSQINVTAPTSPPVQQNIMTPTGPLPDGWEQALTPEGEAYFINHKNKSTSWLDPRLDPRFAMNQQRLSQNAPVKAPPALPPPSPQTGVLGSGGNQQMRLQQLQMEKERLRLKHQELLRQVRPQELALRSQIPPMEQDGGTQNPVCTTGISQELRTMTMNSSDPFLNSGTYHSRDESTESGLSMSSYSVPRTPDDFLNSVDEMDTGEAITQSTIPTQQNRFPDYLETLPGTNVDLGTLEGEAMNVEGEELMPSLQEALSSDILNDMETVLAATKLDKESFLTWL
What is the function of this protein?
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity).  Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (By similarity).  Required for expansion of the neural plate and neural plate border zone progenitor pools.  Acts as a direct regulator of pax3 expression via interaction with tead1 (PubMed:21687713).
What are the official names of this protein?
Transcriptional coactivator YAP1-A, Yes-associated protein 1-A, xYAP, Protein yorkie homolog-A, Yes-associated protein YAP65 homolog A.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.
Protein: MRAY_CHLTA
Sequence: MLPLTYVVKAFSIGLFFSLFLMKPLISWLKKQGFQDHIHKDHCEKLEELHKDKAYIPTAGGIVFVFASVLAVLLLFPIQLWSTWFCIGTILLWGALGWCDDQIKNRRRVGHGLSAKHKFLIQNCLAAGVVLPIMFAYKESFLSFHLPFLGIVSLPHHWWSYLLSFAIATLAIVGTSNSVNLTDGLDGLAAGAMVIACLGMLVVACTNGAPWAFICCVLLATLAGSCLGFLRYNKSPARVFMGDTGSLFLGAMLGMCAVLLRAEFLLLFMGGIFVLESLSVIVQVGSYKLRKKRVFLCAPLHHHYEYKGLSEKAVVRNFLIVELICVVVGIIAVFVD
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUE_DROVI
Sequence: MKLCTSQQFGVAVLFIVLNICSPLADASPIAWDFAVTLRDKILFVDNRWRTIGSAAHEFEELSALAFDEAEELIYFNDQQHQNGSIFSLRRDATVASHIVEQAVQRTGNDSVSGLAYDPLNRNLFWADMRQSKIYFASIDTLYTEPPKVLVDLSAEGGRPDGVAVDICRRQLYWTNCKINHATVERIGLNGTGRETIIKQDIDMPRGIVIDQLSDRIFWIDDKVGIFFALESARLDGSDRQLVLKDKHQSPIQLAITEDTIYWTDKADKAVWSYPKPAYNKPATNSSETQPQPTKLASWKDDVYGIVARTGFYQHLQKDAHCASVVRKVKQRLDNKLNNRTHERSAVEERMDALEREHCLNGASYMSRGNFCICPVGYKGARCEISECHNFCVHGTCEISDMGYPKCYCQEDFYGERCEYYKCNGHCLNDGHCLVDKESGELSCDCRENFTGTRCEHNETAHCASYCQHLKQHPDAFVPASCVDICEELHLSNGTIVTEYQAAAPLCADGPSSLRSGSVIIVLVVGIVSSLALVAVIVHGLRLIYKPKRPRIKKTFVVRKQARLNSASDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQQFAARDRKSPCVKEDKKILIHNMEDDLLT
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS11_CORK4
Sequence: MPPKTRSGARRSGRRVVKKNVANGHAYIKSTFNNTIVSITDPNGAVISWASSGHVGFKGSRKSTPFAAQMAAESAARKAQEHGLKKVEVFVKGPGSGRETAIRSLQAAGLEVNSISDVTPQPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: F167A_DANRE
Sequence: MDASSIPQINIEDFDGLEVAPDDHLRNLKALTEKLRLETRRPSYLEWKERVEAQNTKGLAVSDGSTELEKDAGLKPRATPQRTIEDSQMTAGNGLISRSLGGFDNIDEALVWLRKELMEMRIQDQQLARQLMRLRGDINKLKVEQTCHLHRRMLNDATFGLEERDELSDLLCDGPVTPGFGLSSPLRLIGVTKMNINSRRFSLC
What are the official names of this protein?
Protein FAM167A.
What is the protein family that this protein belongs to?
Belongs to the FAM167 (SEC) family.
Protein: LUXS_HYDCU
Sequence: MPLLDSFTVDHKIMNAPAVRVAKTMKTPGGDTITVFDLRFNKPNVDMMGEKGIHTLEHLFAGFIRAHLNADDVEIIDVSPMGCRTGFYMSLIGTPDEKRVADAWMKAMQDVLNVEKMEDIPELNEYQCGTYTMHSLEEAKSIAQNIIDHGIGVNKNENIALDKETLKALGNDV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.