PharMolix/UniProtQA huggingface dataset:
Protein: TPC1_RAT
Sequence: MSVILDDDVLLILTLDEELSAPLTPSNGLGQEDLPSKNGGGQSGPNSQVPSLVSGADSPPSSPPGHNWEMNYQEAAIYLQEGQNNDKFFTHPKDARALAAYLFVHNHFFYMMELLTALLLLLLSLCESPAVPALKLRTYVHATLELFALMVVVFELCMKLRWLGFHTFVRHKRTMVKTSVLVVQFIEAIVVLVRQTSHVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSTNPSDPYFNTLENSIVNLFVLLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEKHKFKSLLLHKRTAIQHAYHLLVSQRRPAGISYRQFEGLMRFYKPRMSARERFLTFKALNQSNTPLLSLKDFYDIYEVAALQWKAKKNRQHWFDELPRTAFLIFKGINILVNSKAFQYFMYLVVAVNGVWILVETFMLKGGNFISKHVPWSYLVFLTIYGVELFMKVAGLGPVEYLSSGWNLFDFSVTAFAFLGLLALTLNMEPFYFIVVLRPLQLLRLFKLKKRYRNVLDTMFELLPRMASLGLTLLTFYYSFAIVGMEFFSGRLSPNCCNSSTVADAYRFINHTVGNKTKVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKSQESEVDSGIVIEKEMSKEELLAILELHREARGTSSDVTRLLDTLSQMEKYQQNSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQQLRGSAPSPAAQQTPGSRQRSQTVT
What is the function of this protein?
Intracellular channel initially characterized as a non-selective Ca(2+)-permeable channel activated by NAADP (nicotinic acid adenine dinucleotide phosphate), it is also a voltage-gated highly-selective Na(+) channel activated directly by PI(3,5)P2 (phosphatidylinositol 3,5-bisphosphate) that senses pH changes and confers electrical excitability to organelles.  Localizes to the early and recycling endosomes membranes where it plays a role in the uptake and processing of proteins and regulates organellar membrane excitability, membrane trafficking and pH homeostasis.  Ion selectivity is not fixed but rather agonist-dependent and under defined ionic conditions, can be readily activated by both NAADP and PI(3,5)P2.  Required for mTOR-dependent nutrient sensing.
What are the official names of this protein?
Two pore calcium channel protein 1, Voltage-dependent calcium channel protein TPC1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
Protein: GREA_BACLD
Sequence: MAQEKVFPMTETGKKKLEEELEYLKTVKRKEVVERIKVARSFGDLSENSEYDSAKEEQAFVEGRITTLDNMIRNAKIIEDDGANSDIVSLGKTVTFTELPDGEEESYTIVGSAEADPFEGKISNDSPIAKSLLGKQVGDEVTVQTPGGEMLVKIVKIS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: YCIB_BURP0
Sequence: MKFLFDLFPIILFFAAFKLWGIFTATAVAIAATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAVGLVAARYAFGKNLIEKMMGKQLTLPEPVWDKLNLAWAAFFAALGVTNLYVVRNFTESQWVNFKLFGTTGAIVVFVILQSLWLAKYLKEE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LCL3_YEAS8
Sequence: MREGDSNSKKSADVAVLSIILTGSTLTLIYTYKRYLTQFKRTNDIPRRIFRKHWLYGKVTSVGDGDNFHFFHMPGGIRGGWGWLRPVPQMIKNGSTAEKLVGDSRNMRFFNFNWITHGRSTKSKIQKAKSQFLKLNVPYKNRKNLPTIPIRLCGIDAPERAHFGNPAQPFGNEALIWLQNRILGKKVWVKPLSIDQYNRCVARVSYWDWFGGWKDLSLEMLKDGLAVVYEGKVNTEFDDREDKYRYYEFLARSRKKGLWIQNKFETPGEYKKRI
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: RL34_PYRNV
Sequence: MPRPAYRSRSVRRIKVRTPGGRTAVHYEKRAKGAPRCPITGLAIGGMNKKIYRFGVSNRAPTRPYGGVFSHKALARAIRLAVRK
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: YQJE_BACSU
Sequence: MVNEKRLLEEFLELVQIDSETKHEAEICKVLKRKFSDLGVDVKEDDTMDITGHGAGNLICTLKGTKQTDTIYFTSHMDTVVPGNGVKPVVENGYVKTDGTTILGADDKAGLAAMFEAIKVLKEENIEHGTIEFIITVGEESGLIGAKALDRSMITASYGYALDSDGKVGNIIVAAPTQAKVRAAIFGKTAHAGVEPEKGISAITIASKAISKMPLGRIDEETTANIGRFEGGTQTNIVCDEVHILAEARSLVPEKMEAQVQKMKAAFEEAAADMGGRAEVEIEVMYPGFKYQDGDQVVEIAKKAAAKIGRPSELQTSGGGSDANVIAGHGIPTVNLAVGYEQIHTKNEKMPIEELVKTAEMVVAIIEEAAK
What is the function of this protein?
Could be a peptidase.
What are the official names of this protein?
Uncharacterized protein YqjE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: GGGPS_METMA
Sequence: MQVEAHLQKIIEKDGKVHLTLIDPASQTPDRAAEIALAAVEGGTDAIMIGGSTGASGTLLDETVIKIKENIHVPTILFPGSSAGLSKYADAVFFMSLLNSRDLGYVITNQVLGAPLVYRSQIEPISMAYLIVEPGGTVGWVGDAKLIPRKKPEIAAVYALAGKYLGMHYTYLEAGSGADSPVNPEMIGAVKQVLGENKLIVGGGIRNAETAKICTSAGADMIVTGTVVEEVKDVTAKVAEIVSAIKR
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT2_MUNRE
Sequence: MNACLVGIWLWLPLLFTWLSPEVSSSWWYMRATSGSSRVMCDNVPGLVSHQRQLCHRHPDVMRAIGLGVTEWTMECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDNKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGNYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHITRKTKCECKFHWCCAVRCQDCVEALDVHTCKAPKSPDWAAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: UBIG_SHEON
Sequence: MQQNTNVDPQEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAIVDGLDMGEEPLEVARLHALETGVSINYVKNTAEAHREDHREYYDVVTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNVRSFVETIIGAEYLLKMLPIGTHDHNKFIKPSELIDLVDNTELICKDALGITYNPLTGIFKYTSKVDVNYMIATQKVD
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: CAPPA_METHJ
Sequence: MKIPRTMSTQHPDNVHTPFFTENIELTGEDEVKEAYYVYSHLGCTEQMWDCEGKEVDNYVVKKLLSRYGDYFKEHHLGRDLFLTLRVPNPEIERTEAKILLETLGSIPRSYDVAHHFYNDTYAPIFEIILPMTTSFASIDNIYQYYCDFVIGQQYKRLGGRDLTIAEWIGPFHPDKIRVIPLFEDKDGMLAADTILRRYFQDKDLDYQRVFLARSDPAVNYGQIGAVLLNKIALWRLHLLSEDTGIPVYPIIGAGSAPFRGNLRPDTVRRVTDEYAGAYTFTIQSAFKYDTNLEEAVSAIRYLEEREITPAREIDDTYAISLIERYAAGYQKQIRSLAPLINRVAAYIPSRRKRKLHVGLFGYSRNMGGVSLPRAITVTAALYSIGIPPEVLGLSALTENDREFVLENYRYVTEDLSDACRYLNPDSSFLPDEIKKILPDWIEIDPHSEHRVLSGQIEKAVTACQIDSVQDMIIRAGAIRKFLG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: RF3_XANCP
Sequence: MSEVSNEAARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKGRKAARHATSDWMALEKERGISVTSSVMQFPYEDKIVNLLDTPGHADFGEDTYRVLTAVDSALMVIDVAKGVEERTIKLMEVCRLRDTPIMTFINKLDREGKNPIDLLDEVETVLGIQCAPVTWPIGMGQRLKGVVHLITGEVHLYEQGRNFTRQDSTIFPSLDAPGLAEKIGTQMLDELREELELVQGASNPFDLDAYRAGQQTPVFFGSGVNNFGVQPLLDFFVEHAPPPQARDTTGRRVEAVEPKLSGFVFKIQANMDPQHRDRVAFMRVCSGKFTAGMKALHVRSGKDVKLANALTFMASDREIAAEAWPGDVIGIHNHGTISIGDTFTEGESLSFTGIPNFAPELFRRARLRDPLKLKQLQKGLAQLSEEGATQFFRPLMSNDLILGAVGVLQFDVVAYRLKDEYGVDAIFEPVSVTTARWVHCDNPKKLEEFREKNAGNLGIDAAGQLVYLAPTRVNLQLAQERAPDVRFSATREHAYATAVD
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_STAA9
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RS2_JANSC
Sequence: MALPEFSMRQLLEAGVHFGHQTQRWNPRMGEFIYGDRNGIHILDLTQTHPMLEQALQVVRETVAKGGRILFVGTKRQAQKPVADAAERCAQYYMNHRWLGGTLTNWKTVSNSISRLKEIDEKTADGSLEGLTKKERLGMERDQIKLQASLGGIREMGGLPDLIFVIDVNKEDLAIAEAKKLGIPVVAVVDTNCSPDGVDYIIPGNDDAARAIALYCDLISRAALDGMSTQLETAGVDLGALEEGSVEEAIAEEAPAAAEEAPAAEPAAEETPAAEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CEFF_AMYLA
Sequence: MSDKTVPVFSMAELRDGSRQDEFREWARRGVFYLTGYGATERDHRVATDTAMDFFAQGTAEEKQAVTTKVPTMRRGYSALEAESTAQVTNTGTYTDYSMSYSMGIGGNLFPSKEFESVWTDYFDSLYRAAQETARLVLTAAGTYDGEDLDTLLDCDPVLRLRYFPEVPEHRAAEYEPRRMAPHYDLSIITFIHQTPCANGFVSLQAEVDGEMVSLPHVEDAVVVLCGAIAPLVTQGAVPAPNHHVVSPDASMLKGSDRTSSVFFLRPSTDFTFSVPDARKYGLDVSLDMEKATFGDWIGTNYVTMHAVTS
What is the function of this protein?
Hydroxylation of desacetoxicephalosporin C in 3'position to form deacetylcephalosporin C.
What are the official names of this protein?
Deacetoxycephalosporin C hydroxylase, Beta-lactam hydroxylase, Deacetylcephalosporin C synthase, DACS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: SBMC_CROS8
Sequence: MDYTIEHVLTRKIAGFHLVGPWEKTVPQGFEQLSLWVDNFHIQPQAWLAVYYDNPQQVAPEKLRADTVVEVPADFTLPENSVGVILTDLPGGQYAVARARVENNDFGTPWLAFFTRLHQDVRYQMAARPCFEIYLNDGKRDGYWDIDMYIPVQTSGE
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_STRPG
Sequence: MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLASQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_ECO7I
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: ATPL_YERE8
Sequence: MENLNMDLLYMAAAIMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GMHA_SULDN
Sequence: MKKYIKEQIKKSFEIKQTIYENENLINKIEEVSKLCVALYRGDKKTILAGNGGSAADAQHIAAELVGRYGFDRPSIPSLALTTDTSCLTAIGNDYGYDNVFSRQLEGMGQAGDIFIGISTSGNSKNIINAFISAKKKGITTVALVGRDGGEMAKMADVALVVPSDSTPRIQESHILIGHIICDIIEKEIFGDGVN
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_TRIEI
Sequence: MSRYRGPRLRIVRRLGDLPGLTRKSARRAYPPGQHGQNRRKRSEYAIRLEEKQKLLYNYGVCERQLLRYVKKARRAGGSTGKVLLELLEMRLDNTVFRLGMAPTIPSARQLVNHGHVTVNGKVVSIASYQCKPGEVISVKEKEKSKEMVKTNLQYPGLANIPSHLEFDKNKLVGKVNGIVEREWVALQINELLIVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL1_LACDA
Sequence: MPKHGKKYVEAAKKVDSNKLYSVEDAIKLVKETSYANFDASVEVSYNLSVDPKQADQQIRGSIVLPNGTGKSVKVIVFAEGPQAEAAKAAGADEVGADDLVEKVQNGYLDFDVVIATPMMMAKVGRLGRVLGPKGLMPNPKTGTVTMDTAKAVQNVKAGQVEYRVDRQASIHTAIGKVSFTEEQLTENFRALQNAILRAKPASAKGQYIKSCAVAATFGPGIKLDPIALMA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: KEFF_ECOBW
Sequence: MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MOC2B_DROPS
Sequence: MNHIKLIDCPIDVTYAINLISDPSCGASSIFIGTTRDSFQGKKVVSLAYEAYENMALKEMDKICSDLRATWPDLKHILIYHRLGTVPENEASVVIAASAPHRSAALKAVTFAIDQLKSRVPIWKKEIYEGNHDAEWKENSESIRPKKSLSSFNYSVCKVDESRVVSRNLVQIRANDCELKNRVECFFKRKRAEINSCNVIDFKQSNLSSNINSDTEVDVSCARTQSTISKQEQSNCHLKVRRATNRCGPQQMQFRPEYKHELSRLTASRVSTNEVGESLQNSRLHSIETYMGLTSKNNENIINRIKNVENRILLLESTSPEYQHFFEQSCMDQPEKKIKTNKTYSAHELRVYIHRKNKECP
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated Mocs2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3801_YERPN
Sequence: MDEWYGQVAPREKLLKYGAAVLTDAELLAIFLRTGIPGMHVMKMAEYLIETFGSLHGLISADYQTLCAHKGIGASKYSQIQAIGELACRCFSSHLMRESVLLNPGITQKFLQNILSHREREIFLVVFLDNQHRVIRHEEMFTGTISSVEVHPREIVREALKVNAAALILAHNHPSGKAEPSQADRLITTQVIKACSLLDIRVLDHLVVGRGECVSFAERGWL
What are the official names of this protein?
UPF0758 protein YPN_3801.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: UL35_HCMVA
Sequence: MAQGSRAPSGPPLPVLPVDDWLNFRVDLFGDEHRRLLLEMLTQGCSNFVGLLNFGVPSPVYALEALVDFQVRNAFMKVKPVAQEIIRICILANHYRNSRDVLRDLRTQLDVLYSDPLKTRLLRGLIRLCRAAQTGVKPEDISVHLGADDVTFGVLKRALVRLHRVRDALGLRASPEAEARYPRLTTYNLLFHPPPFTTVEAVDLCAENLSDVTQRRNRPLRCLTSIKRPGSRTLEDALNDMYLLLTLRHLQLRHALELQMMQDWVVERCNRLCDALYFCYTQAPETRQTFVTLVRGLELARQHSSPAFQPMLYNLLQLLTQLHEANVYLCPGYLHFSAYKLLKKIQSVSDARERGEFGDEDEEQENDGEPREAQLDLEADPTAREGELFFFSKNLYGNGEVFRVPEQPSRYLRRRMFVERPETLQIFYNFHEGKITTETYHLQRIYSMMIEGASRQTGLTPKRFMELLDRAPLGQESEPEITEHRDLFADVFRRPVTDAASSSSASSSSSSASPNSVSLPSARSSSTRTTTPASTYTSAGTSSTTGLLLSSSLSGSHGISSADLEQPPRQRRRMVSVTLFSPYSVAYSHHRRHRRRRSPPPAPRGPAHTRFQGPDSMPSTSYGSDVEDPRDDLAENLRHL
What is the function of this protein?
Promotes cytoplasmic UL82 accumulation and inhibits UL35-containing nuclear bodies formation (PubMed:21489587).  Regulates viral assembly by controlling the localization of the essential gB through regulation of a retrograde transport pathway.  This modulation occurs via binding and inhibition of host sorting nexin 5/SNX5 (PubMed:29444945).
What are the official names of this protein?
Protein UL35.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae pp85 family.
What are the subcellular locations of this protein?
[Isoform UL35]: Virion tegument. Host nucleus. Host cytoplasm. Note=Found in nuclear bodies. SUBCELLULAR LOCATION: [Isoform UL35A]: Host nucleus. Host cytoplasm.
Protein: FSLJ_DICDI
Sequence: MVSNKNLLPIIYIFFIILYFGDVAKSQYFPLDKGATCQKYRGDSPGIQLCDGFLSNPNSIYINSTSSQEAIQAQGNLVRQYINFYKSFESCKNPRTFALLCAFLFPECEKYTDPVSKVTYAYPILPCYNNCLNMTTSCQISTSRLSCATKYTFENISYSVFPKNTTTYQIDSLSYTNTCENTDLIANSQNTSIQQCFEPLVYHVSTDEIHDKSIGYIFPSTNTTCVVGCPAPLYYANQWRNIYRLSDVLSILSCILTLFLVITLGIINPKVSRFDKINVMLLSSIFLQAFSGALMTFNGTENTLCPEDGRFASYIDRMCVATGFLLHGSSLLVVQWWCVLSFEVWFTIFQVGKKQKDRFIYYLVASLIIAWIPPIVSISKNEYSGGPANPFCWLTTFNYRRFAFWLPMGIFLCLGGVFLILLMREIYVIVSGNVQSTKESRFKVLKMEAKPIISLIMYFSCLLYLFIYDQWINNHMHVYTDSIPSYALCLLTSTSTNDCLLKAPDITGLGYFIYSIRVFGVYAFIIYGISKKTLQIWKYNYFVVFIGQKIEQFTNATTTAKSSNSNNSSTTNNISVKASSNMEYETRQENENGDSQSVELDSNSDAL
What are the official names of this protein?
Frizzled and smoothened-like protein J, Cell number regulator protein A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TBP_DANRE
Sequence: MEQNNSLPPFAQGLASPQGAMTPGLPIFSPMMPYGTGLTPQPVQNSNSLSLLEEQQRQQQQQQAASQQQGGMVGGSGQTPQLYHSTQAVSTTTALPGNTPLYTTPLTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRGEIYEAFENIYPILKGFRKTS
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity).  Members of the TBP family are differentially required for transcription and development during early embryogenesis.  Regulates mRNA levels in the early embryo by both transcriptional and post-transcriptional mechanisms.  Required for transcription of a subset of genes at the mid-blastula transition (MBT).  Negatively regulates the expression of other embryonic genes, including autoregulation of the tbp promoter itself.  Also functions within a transcription-dependent mechanism to direct the temporally-regulated degradation of a subset of maternal mRNAs after the MBT.  This is part of a general mechanism to regulate the maternal to zygotic transition and is required for normal embryonic development.  Binds to promoters of a subset of genes.  Required for gastrulation.
What are the official names of this protein?
TATA-box-binding protein, zTBP, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, zfTBF, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAE_BLOPB
Sequence: MSYIVALTGGICSGKSVVAKKFSNLSKKVSVIDADVISKNITQPGSIALRMITKHFGPHILFSNGSLNRSMLKKIIFFNPKDKEWLEQLLHPLIRKETQKTINILSNRSSYILWVVPLLIENNLQKYADHILMIDVHVDIQLNRIISRDKIHKQYAENILLSQVSRQHRLNYADNVIENNKSIDGMTQHIHNLHRDYLKAEKTTTKKTIFSK
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.