PharMolix/UniProtQA huggingface dataset:
Protein: RPO11_SULTO
Sequence: MEIKILRSGENYLELQIDGEEHTVGNLLKGYLLKVPGVKFASYSKPHPLIDSIILKIMTDGSISPKEALVKAIELAEEDTNKFIEEVKSIEKR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2H2_ARATH
Sequence: MSNQRKRSNDEREEEDDEDAEGIGEWERAYVDDRSWEELQEDESGLLRPIDNSAIYHAQYRRRLRMLSAAAAGTRIQKGLIRYLYIVIDFSRAAAEMDFRPSRMAIMAKHVEAFIREFFDQNPLSQIGLVSIKNGVAHTLTDLGGSPETHIKALMGKLEALGDSSLQNALELVHEHLNQVPSYGHREVLILYSALCTCDPGDIMETIQKCKKSKLRCSVIGLSAEMFICKHLCQETGGLYSVAVDEVHLKDLLLEHAPPPPAIAEFAIANLIKMGFPQRAAEGSMAICSCHKEVKIGAGYMCPRCKARVCDLPTECTICGLTLVSSPHLARSYHHLFPIAPFDEVPALSSLNDNRRKLGKSCFGCQQSLIGAGNKPVPCVTCRKCKHYFCLDCDIYIHESLHNCPGCESIHRPKSVSLMEE
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription (By similarity).  Can restore UV resistance in the NER-deficient ssl1-1 yeast mutant (PubMed:16623910).
What are the official names of this protein?
General transcription factor IIH subunit 2, AtGTF2H2, TFIIH basal transcription factor complex p44 subunit, Atp44.
What is the protein family that this protein belongs to?
Belongs to the GTF2H2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ODPA2_ARATH
Sequence: MALSRLSSRSNTFLKPAITALPSSIRRHVSTDSSPITIETAVPFTSHLCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEALAVGMEAAITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYKKDASFYGGHGIVGAQIPLGCGLAFAQKYNKDEAVTFALYGDGAANQGQLFEALNISALWDLPAILVCENNHYGMGTATWRSAKSPAYFKRGDYVPGLKVDGMDALAVKQACKFAKEHALKNGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKLLLTHDIATEKELKDMEKEIRKEVDDAVAQAKESPIPDASELFTNMYVKDCGVESFGADRKELKVTLP
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha-2, mitochondrial, PDHE1-A, Protein IAA-CONJUGATE-RESISTANT 4.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GPMI_BACC1
Sequence: MRKPTALIILDGFGLREETYGNAVAQAKKPNFDGYWNKFPHTTLTACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFDKNETFQSAIKSVKEKGTALHLFGLLSDGGVHSHMNHMFALLRLAAKEGVEKVYIHAFLDGRDVGPKTAQSYIDATNEVIKETGVGQFATISGRYYSMDRDKRWDRVEKCYRAMVNGEGPTYKSAEECVEDSYANGIYDEFVLPSVIVNEDNTPVATINDDDAVIFYNFRPDRAIQIARVFTNEDFREFDRGEKVPHIPEFVCMTHFSETVDGYVAFKPMNLDNTLGEVVAQAGLKQLRIAETEKYPHVTFFFSGGREAEFPGEERILINSPKVATYDLKPEMSIYEVTDALVNEIENDKHDVIILNFANCDMVGHSGMMEPTIKAVEATDECLGKVVEAILAKDGVALITADHGNADEELTSDGEPMTAHTTNPVPFIVTKNDVELREGGILGDIAPXMLTLLGVEQPKEMTGKTIIK
What is the function of this protein?
Essential for rapid growth and for sporulation.  Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: Y1283_VIBPA
Sequence: MIYTTTDTIPGKEIAEVRGVVTGNVVQSKHIGRDLMAGLKSIVGGEIRGYTEMMTEARDIAIQRMVEQANQKGADAIVGIRFTTSSIVDGSSEILAFGTAVKLVE
What are the official names of this protein?
UPF0145 protein VP1283.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RS7_MARMM
Sequence: MSRRHRAEKREIFPDPKFGDRDLTKFMNYIMLDGKKSVAERIVYGALEIVEEKLKREPIRVFHDALDNVAPEVEVRSRRVGGATYQVPVEVRAERKKALAIRWLTGAARGRNENTMRERLAAEMMDASANRGTAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YCF4_TRIEI
Sequence: MTTQTSTGDRLVHQEIIGSRRLSNYLWAIIVTMGGIGFLLSGISSYLKVNLLIVADPTQLNFLPQGIAMSFYGLLGTIYGIFLWLTVIWDLGGGYNDFNQESGQIMIFRRGFPGKNRKVEFNCTTENVQSIKVDIKEGLNPRRAIYLCLKDRRQIPLTRVGQPLALSKLENEAAQLAKFLQVPLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SUI1_PYRFU
Sequence: MPRIVNPLDEMLFKEVLKEQQRIRVYTERARYGKIKTIIEGIDEKEFDLEEIAKKLKAKLACGGTAKNGRIELQGDHRDRIKKLLVELGFSEELIEVE
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: TATA_RHORT
Sequence: MGFSSIWHWIIVLVVVLLLFGAGKIPRLMGDVAKGVKAFKKGMADDEDDEAASVSAERRGIEDGKPAQTIYPPQQPQQPQQPPQQPPVHRDDAPRG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ISPE_PARDP
Sequence: MPLHRREAAPAKLNLTLHVTGRRVDGYHLLDSLVVFLDLGDVVTIAPGPLSLSLTGPFAPGLAAEPDNLCLRAARLAGREARITLEKNLPVASGIGGGSADAAAVLRALDASPRRPEALGADVPVCLASRPVRMRGVGEILAPLPALPELNVLLVNPGRGLSTPAVFKALARHDNPPMPEPLPDFPDAQALIGFLHECRNDLEAPAIALMPGIADCLAALRSAGAQLARMSGSGATCFGLFASAAEAQAARARIAGTNPGWWVAASGLAPAKH
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ATPB_CYAM1
Sequence: MSGKVVQIIGPVLDIEFPSGQLPKLLNAIVVRDGEKSVTCEVQQLLGDNRVRAIAMSSTDGLRRGIQAEDTGAPISVPVGKVTLGRIFNVLGDCVDNLGTVTRQAVQPIHKQAPSFVQLETKPSVFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFAGVGERTREGNDLYEEMKASGVIQSQNLSESKVALCYGQMNEPPGARMRVGLTALTMAEHFRDINKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTVDGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPNIVGEAHYQTASRVKQTLQRYKELQDIIAILGLDELSEEDRLLVARARKIERFLSQPFFVAEVFTGSPGKYVSLEESIKGFKMILDGELDDLPEQAFYLVGNIEEAIQKAQKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DAPB_NITOC
Sequence: MIRVAISGAAGRMGRSLIQAACQYEGITLGAASEYPDSHLIGSDAGEVARVGALQIPLVDDLGKNKEAFDLLIDFTRPEVSMANLVLCRDQGKAMVVGTTGFTKEQRQEITRAAIEIPIVLAPNMSVGVNLCLKLLEMAASVLKDDVDIEIIEAHHRHKVDSPSGTALRMGEVVAETLGRNLDQCAIYGRQGLRSERPRESIGFSSLRAGDIVGEHTVIFAAEGERIEISHKASSRMTFALGAMRASQWVSDKPPGLYDMQDVLGLLKKVN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y181_METJA
Sequence: MEKIFNISFSMPKSYELKDFIKQYDFFNDDKIAEKLERFFKAINFTNPRHLKKVLNKYAILIEFKNSKIDNERLIPEIIRIENGERKRKGYLFDTVFVLYFIILYEFYYGKYLEVKRYKCRLQTNTGLQSYFERYSLLSQIMKVIKNRNANDMDRVITNLMLLYSQLGYRYNYEIKGRKFYKLVINREIRDKDYNIANELSIELKEAGITVDFWEYIKNNYEDLIEENYPNPYPFTNLFKMVETYL
What are the official names of this protein?
Uncharacterized protein MJ0181.
Protein: FABH_CLOD6
Sequence: MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKERRFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGAVNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFGDGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAGSDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYVNIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NISR_LACLL
Sequence: MVYKILIVDDDQEILKLMKTALEMRNYEVATHQNISLPLDITDFQGFDLILLDIMMSNIEGTEICKRIRREISTPIIFVSAKDTEEDIINGLGIGGDDYITKPFSLKQLVAKVEANIKREERNKHAVHVFSEIRRDLGPITFYLEERRVCVNGQTIPLTCREYDILELLSQRTSKVYTREDIYDDVYDEYSNALFRSISEYIYQIRSKFAPYDINPIKTVRGLGYQWHG
What is the function of this protein?
Member of the two-component regulatory system NisK/NisR involved in the regulation of the biosynthesis of lantibiotic nisin.  NisR may function as a regulatory protein.
What are the official names of this protein?
Nisin biosynthesis regulatory protein NisR.
Protein: UPPP_GEMAT
Sequence: MTVWQAIVLGIVQGLTEPLPVSSSAHLALTPYFLGWSDPGLAFDVALHFGTLLALIWYFRREWLEMIASAWRIARTRRVETVHDRRVLYLIAATIPGGIGGLLLNDLAETTFRSPVVIATSLIVMGILLWAVDRWSARARVLEEVTLRDAIIVGCAQVLALVPGVSRSGSTMTAGRLLKLDRPSVARFSFLMSMPITLAAVIVKMPDAVREHGASLPLLAGVAAAAVSSWFAISVLLRYVARHSFGVFAVYRVLLGIVVFATLASRT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBIB_VIBVU
Sequence: MTPTELKRLYRIIKVQLEYGLDDLLPDHQLAKAPRWMRKSLFWLKNQHPEKPLGDRLRLALQELGPVWIKFGQMLSTRRDLFPPHIADPLALLQDQVSPFDGALAKAQMEQALGGPLETWFSDFDLVPLASASIAQVHTAKLKTTNQEVVLKVIRPDIRPIIDADLKLMRRMARIVAKAMPEARRLKPIEVVREYEKTLLDELDLRREAANAIQLRRNFTDSEELYVPEVYPDFSNETVMVSERIYGIQVSDIAGLKANGTNMKLLAERGVSVFFTQVFRDSFFHADMHPGNVFVNPEHPENPQWIGLDCGIVGTLNSEDKRYLAENFLAFFNRDYRRVAELHVDSGWVPADTNIDEFEFAIRIVCEPIFAKPLCEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWETAKPFLEEWMMNQVGPKALINAIKDRAPYWAEKLPELPELLYDSLKQGKAMNQRMDQLYQGYRASKRQQATGKFLFGVGATLVVCSAILVDHTYEQLSLATAIAGVTFWLFSWRAYRR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL33_CHLTB
Sequence: MASKNREIIKLKSTESSEMYWTVKNKKKTSGRLELKKYDRKLRKHVIFKEAK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS7_SHIFL
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RLME_RICRS
Sequence: MTNNLSGYRNKFVRVKTSKKRTVSSSNWLRRQLNDPYVAKARIDGFRSRAAYKLLEIHEKFKLFTPNMKVVDLGAAPGGWSQVASKLIKASDNNLNNKIISIDVLEIEHVAGVEFVQKDFFEADTEELIIQALDGRADIVMSDMASNTIGHKATDHIRTLLLCEQAFEFALKVLKPSGHFIAKIFRGGAENELLHKVKREFKTVKHFKPSSSRSESTEIYLVALNKK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_CHLTE
Sequence: MKIYSSIKKRCEHCRIIKRKGKRFVICKVNPSHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL331_STRPN
Sequence: MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTLHLESK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ATPI_ARAHI
Sequence: MNVLSCSINTLIKEGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSAVLAVRNPQTIPTDGQNFFEFVLEFIRDVSQTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPQGELAAPTNDINTTVALALLTSAAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSBE_STIHE
Sequence: MSGKPNERPFSDIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDIFGAPRPNEYFTEDRQDAPLITDRFNALEQVKQLSQQ
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL3_HAHCH
Sequence: MAIGLVGRKAGMTRLFEDDGAAVPVTVIQVEKNVIAQVKSLEVDGYRAIQVTSGSVKASRVNKPMAGHFAKAGVEAGRVVCEFTLDATDSAEYKVGDEVSVTIFEAGQKVDVSGRSKGKGFAGVIKRWNFSTQDATHGNSLSHRAPGSIGQNQSPGRVFKGKKMAGQMGNKNVTVQTLKVVRVDEEKGLLLIKGAVPGATGADVVIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GGP4_ARATH
Sequence: MAEQKKYLLFLATPDSEFAKKTYGGYHNVFVSLLGDEGEQWDSFRVVDGEFPEEKDLEKYEGFVISGSSHDAFQDTDWILKLCDIIKKLDDMNKKVLGICFGHQLIARAKGGKVARARKGPELCLGNITIVKEAVMPENYFGEEVPANLRIIKCHQDEVLELPENAKLLAYSSMYEVEMYSIKDNFLCIQGHPEYNRDILFDIIDRVLAGGHIKQNFAETSKATMEKNEADRKFWQKICKNFLKRQPSLLV
What is the function of this protein?
Involved in glucosinolate biosynthesis.  Hydrolyzes the gamma-glutamyl peptide bond of several glutathione (GSH) conjugates to produce Cys-Gly conjugates related to glucosinolates.  The gamma-Glu-Cys-Gly-GSH conjugates are the sulfur-donating molecule in glucosinolate biosynthesis.
What are the official names of this protein?
Gamma-glutamyl peptidase 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GLMM_BRADU
Sequence: MSRKYFGTDGIRGRANGLITPELALKVGQAAGLAFQRGDHRHRVVIGKDTRLSGYMIEYAMVAGFTSVGMDVLLVGPMPTPAVAMLTKSMRADLGVMISASHNLFEDNGIKLFGPQGFKLSDDVEKQIEQLLDEPIDKRLAQSASLGRARRIDGVHDRYIEFAKRTLPRDLSLDGLRVVVDCANGAAYKVVPEALWELGADVVPIGVEPDGFNINKDCGSTSPEALSKKVREMRADIGIALDGDADRVILVDERGHVVDGDQLLAVIAQSWKEDGRLSRPGIVATVMSNLGLERFLKGQGLDLVRTPVGDRYVLEQMLSGGYNLGGEQSGHIILSDYATTGDGFVAALQVLAVVQKSRRPVSEVCHRFDPLPQILKNVRHKGGKPLDDSDVKSAISDGEKRLNGHGRLLIRSSGTEPVIRVMGEGEDRILVEDVVDTIVSALGQAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ANR46_MOUSE
Sequence: MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPELVH
What are the official names of this protein?
Ankyrin repeat domain-containing protein 46, Ankyrin repeat small protein, ANK-S.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EXO84_YARLI
Sequence: MSLEPPNQSLRSHRQTANPHVMAAAVQKQKPYIQDSTHLQLPNVGDKDRERVGNMVKRRFSARIPGQGVPYDAAAAPSLPVGAGSMIDDAVAAGGVPVTKSKTMTSPAKAAPVASGASGMLLKEDLDAHTFVTQQLATSNAEEVDRFVSKLKSLKSRLVDEQREAMYTNYNSFLTVNKEILALNSEVKSLGQAVSNFNVAVSAMVEDALESTSSKSQESSQSSLALPDSSARNRNSMVMLENMWANELASLFKHVEGAVKYLPAIPGRHVVAESGAWYQLNAATWKPLRPVHMFLLNDHLLIAAKNRKKDNMQMQQTQTLVADQCWPLSDIEFLDLSVSRRGTHPVVPNAVSVVCGGVTCVYQTEKPAQHAKVVSAFKKVAGEGRKNDTNKTQQQIRLRESMTYYAARNPSLRGHKELLQGLSNSKGHSRSSSVDITGRTKNLREIDDLVNDLDVKIAHRRFAEATDIILENIKDDKESTDITQQVLDIKLHQRQDELVAHLIDDVATDTSNTAVTHALGLLVRLGHGDQARGVYLETRRNLIHKRTRQVELLGDIPGYIAQVAVTYFRLIRSTAEVFRKCYTDNHLASSIAEWAKSMVEEFVLLFARQLYGVKPDTQTYQQCVSITRQQAAQLSEVGLNLDYLLDYVLSPARASKA
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis.  Also involved in assembly of the spliceosome (By similarity).
What are the official names of this protein?
Exocyst complex component EXO84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of EXO84 requires actin cables (By similarity).
Protein: MCAL_CERSK
Sequence: MSFRLQPAPPARPNRCQLFGPGSRPALFEKMAASAADVINLDLEDSVAPDDKAQARANIIEAINGLDWGRKYLSVRINGLDTPFWYRDVVDLLEQAGDRLDQIMIPKVGCAADVYAVDALVTAIERAKGRTKPLSFEVIIESAAGIAHVEEIAASSPRLQAMSLGAADFAASMGMQTTGIGGTQENYYMLHDGQKHWSDPWHWAQAAIVAACRTHGILPVDGPFGDFSDDEGFRAQARRSATLGMVGKWAIHPKQVALANEVFTPSETAVTEAREILAAMDAAKARGEGATVYKGRLVDIASIKQAEVIVRQAEMISA
What is the function of this protein?
Involved in the ethylmalonyl-CoA pathway for acetate assimilation.  Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA (By similarity).
What are the official names of this protein?
L-malyl-CoA/beta-methylmalyl-CoA lyase, (3S)-malyl-CoA/beta-methylmalyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: IF2_XANCP
Sequence: MLWARGRQPDHRIRMSQQTTIRKLAELVNTPVDKLLVQLAEAGMKFSGPDQVVTSTEKMKLLGFLRRTHGKADTPAEAASEAAKKITLNRRKLQEVTVNAGRTKTTVNVEVRQKRTYVKSENEGSGRAAPMTPDEERADILAKLAASRQRNLDEQQRLAESDRARDEAIQRKRDEEQAAKDRVEAERKAAEEAAAAASAPAPVAAAPAPSSAPAARAPSSPSSAPRPARPAGASPASRPATPARPDDRNNAAKHKTRGSHVMVAGVEDDDATKRFAGQLHLSAADRARRSNVRGKPTGRPGSSSSRRNDGGRGSNQSNSGPHGFERPTAPVVREVAIGETITVADLAQKLALKGGDVVKALFKMGVMATITQSIDHDTAALVTEELGHKAVRADNADFEDALLAHAEDAQGETTSRPPVVTIMGHVDHGKTSLLDYIRRTKIASGEAGGITQHIGAYHVETGRGVISFLDTPGHAAFTSMRARGAKITDIVVLVVAADDGVMPQTKEAVAHAKAAGVPLIVAVNKIDKAGADPLRVKNELLAENVVAEDFGGDTQFIEVSAKVGTGVDTLLDAISLQAEVLELKAVADGRASGTVIESSLDKGRGPVATVLVQQGALKRGDYLVCGIQYGRVRALFDETGHQPASAGPSIPVQVLGLSGVPEAGDDFVVVDDERLAKDVAQQRETKRRESRLVASATNRMEDILAQMGKGEGQQVLNLVIKADVQGSVEALKQSLVALSNDDIRINVIHSGVGGITESDANSAAASKATIIGFNVRADASARKIVESNGIDLRYFSIIYDVIDQVKQVASGLLGVEIREEIIGIAQVRDVFRSSKFGAVAGCMIIEGVVKRSKPIRVLRDSVVVFEGELESLRRFKENVDEVRNGTECGIGVKAYNDVKAGDQIECFERIEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_CAUVC
Sequence: MVKPIHVLSGPNLNLLGTREPEIYGKDTLDDVRTRCEARAASRGVSVVFRQSNHEGVLIDWVHEARESASALVINPAGYGHTSIALLDALKTLSIPVIECHLSNPAAREEFRRHTYVSLAATGIVSGFGAASYELAIEAAFGLIRA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.