PharMolix/UniProtQA huggingface dataset:
Protein: UVRA_NEIMB
Sequence: MCNHHPQHSHDNDTIRIRGARTHNLKNIDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPTVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLATGAIDGWDKRNQFYFQMIQSLARHYGFDVQAAWETLPEKVKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIADTPENVAQCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPFDDIHGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRIIAKGSPEQVAKVKGSYTGKYLKVVLR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRUP_PHOPA
Sequence: MRLHTGEKPYQCLHCDRHFVQVANLRRHLRVHTGERPYACEICPSR
What is the function of this protein?
Krueppel is a gap class segmentation protein.
What are the official names of this protein?
Protein krueppel.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPOL_HBVA3
Sequence: MPLSYQHFRKLLLLDDGTEAGPLEEELPRLADADLHRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPIFNPEWQTPSFPKIHLQEDIINRCQQFVGPLTVNEKRRLKLIMPARFYPTHTKYLPLDKGIKPYYPDQVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHGRLVIKTSQRHGDESFCSQSSGILSRSSVGPCIRSQLKQSRLGLQPRQGRLASSQPSRSGSIRAKAHPSTRRYFGVEPSGSGHIDHSVNNSSSCLHQSAVRKAAYSHLSTSKRQSSSGHAVEFHCLPPNSAGSQSQGSVSSCWWLQFRNSKPCSEYCLSHLVNLREDWGPCDEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGISRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRINNNQYGTMQNLHDSCSRQLYVSLMLLYKTYGWKLHLYSHPIVLGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHRESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGYIIGSWGTLPQDHIVQKIKHCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLSKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCTANWILRGTSFVYVPSALNPADDPSRGRLGLSRPLLRLPFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: YL174_MIMIV
Sequence: MYYKYIFQNGYLKHIKIFMTVFMELLRLLNHINLYNIIHHEELFENGIDNETFFYLFKIGFLGDIIDIINHVVSNTKTITVDFMDKILVVYKNKLIQYAIDDICINSACYDKIYKILIDKSLETDNLNLFNFIVKELDTVFMDVDESKLTFRQKNRLDSIKNKHSYNSTRINSIIKICLSKHSPVKNCPKIFSQLITDLGGVMEMIDHDFYKIFYRGIINYAEIVCENLIHTSPELIDDLLLKARRMEMFQLLVDHGANYKKIYKTTPDEKQKKSLKRFINNLKDKEYLEDIDDIDDSDESDDSDDSEDSDSFGDSDSSGNSEDSEDSDNSE
What are the official names of this protein?
Uncharacterized protein L174.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17x/L18x family.
Protein: GLMS_ACIFI
Sequence: MCGIVGGVSKTDLVPMILEGLQRLEYRGYDSAGLAILGADADLLRVRSVGRVAELTAAVVERGLQGQVGIGHTRWATHGGVRECNAHPMISHEQIAVVHNGIIENFHALRAHLEAAGYTFTSETDTEVIAHLVHHYRQTAPDLFAATRRAVGDLRGAYAIAVISSGDPETVCVARMGCPLLLGVADDGHYFASDVAALLPVTRRVLYLEDGDVAMLQRQTLRITDQAGASRQREEHWSQLSAAAVDLGPYRHFMQKEIHEQPRAVADTLEGALNSQLDLTDLWGDGAAAMFRDVDRVLFLASGTSHYATLVGRQWVESIVGIPAQAELGHEYRYRDSIPDPRQLVVTLSQSGETLDTFEALRRAKDLGHTRTLAICNVAESAIPRASALRFLTRAGPEIGVASTKAFTTQLAALYLLALSLAKAPGASERCAAGGSPGRLRQLPGSVQHALNLEPQIQGWAARFASKDHALFLGRGLHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVDRDMPVVVIAPNDRLLEKLAANMQEVHARGGELYVFADSDSHFNASAGVHVMRLPRHAGLLSPIVHAIPVQLLAYHAALVKGTDVDRPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1603_HAEIN
Sequence: MAMNNILGLFAHSPLKPLQKHSEKVTECSDLLIPFFQTTFSKNWEQAEEKRLEISQCEREADSLKREIRLKLPRGLFLPIDRTDLLELVTQQDKLANYAKDIAGRMIGRQFGIPEEMQEEFLHYVKRSLDAIHQAHRVIEEMDKLLETGFKGRELKLVNDMIQELDSIEDDTDQMQIKLRKMLYTIESRYNPIDVMFLYKIIEWVGVLADQAQRVGSRIELMLARS
What are the official names of this protein?
UPF0111 protein HI_1603.
What is the protein family that this protein belongs to?
Belongs to the UPF0111 family.
Protein: SCUB3_HUMAN
Sequence: MGSGRVPGLCLLVLLVHARAAQYSKAAQDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYTGDGKHCKDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTCIQRPEEGMNCMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTEPLKCQGSPGASKAMLSCNRSGKKDTCALTCPSRARFLPESENGFTVSCGTPSPRAAPARAGHNGNSTNSNHCHEAAVLSIKQRASFKIKDAKCRLHLRNKGKTEEAGRITGPGGAPCSECQVTFIHLKCDSSRKGKGRRARTPPGKEVTRLTLELEAEVRAEETTASCGLPCLRQRMERRLKGSLKMLRKSINQDRFLLRLAGLDYELAHKPGLVAGERAEPMESCRPGQHRAGTKCVSCPQGTYYHGQTEQCVPCPAGTFQEREGQLSCDLCPGSDAHGPLGATNVTTCAGQCPPGQHSVDGFKPCQPCPRGTYQPEAGRTLCFPCGGGLTTKHEGAISFQDCDTKVQCSPGHYYNTSIHRCIRCAMGSYQPDFRQNFCSRCPGNTSTDFDGSTSVAQCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECGDVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDEDYEQLVEDIVRDGRLYASENHQEILKDKKLIKAFFEVLAHPQNYFKYTEKHKEMLPKSFIKLLRSKVSSFLRPYK
What is the function of this protein?
Is a positive regulator of the BMP signaling pathway, required for proper chondrogenesis, osteogenesis and skeletal development.  It acts as coreceptor for BMP ligands, particularly BMP2 and BMP4, facilitating their interactions with BMP type I receptors (PubMed:33308444).  It is required for ligand-induced recruitment of BMP receptors to lipid rafts (By similarity).  Binds to TGFBR2 and activates TGFB signaling.  In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.
What are the official names of this protein?
Signal peptide, CUB and EGF-like domain-containing protein 3.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: YOPH_YERPS
Sequence: MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANVVLTQEDTAKLLQSTVKHNLNNYDLRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSALHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVGDDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
What is the function of this protein?
Essential virulence determinant.  This protein is a protein tyrosine phosphatase.  The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation.  It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
What are the official names of this protein?
Tyrosine-protein phosphatase YopH, Virulence protein.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system.
Protein: S72L2_HUMAN
Sequence: MLSSTLRVAVVCVSNVNRSMEAHSILRKKGLSVRSFGTESHVRLPGPRPNRPVVYDFATTYKEMYNDLLRKDRECYTRNGILHILGRNERIKPGPERFQECTDFFDVIFTCEESVYDTVVEDLCSREQQTFQPVHVINMEIQDTLEDATLGAFLICEICQCLQQSDDMEDNLEELLLQMEEKAGKSFLHTVCFY
What is the function of this protein?
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II.  Plays a role in RNA processing and termination.
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 2, RNA polymerase II subunit A C-terminal domain phosphatase SSU72L2, CTD phosphatase SSU72L2.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
Protein: JBP2_LEIBR
Sequence: MPSGLMRANTSTELESILDIVQSSGEIAVVFTSPSIGDLETITSETQRRQLRIAGIPRGGYTILPAIPLYDDELLQMCERYTAASEHEKVEIRNSLYMREYPLFAYSMRNQRALFHPADYVSRILQFCFHYVQVPDEDVLSLQDRSPFLHISPVKEICVHLRLIVRGTPAAPDESESPVPEQLHFHAESDAEKLAAERARALSIAASSGGASETEPLSLFTGVAPSALFQKGAVEEVDLDTEETIEDLTGEETVDAVHSFHSEYLTLSGFELVTKASIFYDHEGEGQRVVAVYIPGGVPKETCRAAAAVLELAVTKKNLRAATNGGLPPDTGIVGYYDYLTNPTQHKCRETEFSRRNWGLFSQSESLLKHLDKLYSQLAPTHHHLQRVAIPSQYQLCGTVFSTITVNRNFRTAVHTDKGDFRSGLGVLSVINGEFEGCHLAIKSLKKAFQLKVGDVLLFDTSLEHGNTEVVHPENHWQRTSIVCYLRTGLMSSVCEMERRKHLNRLILQQLLNTEIRHTTVNINEADSSLPPLFVPTRLASQLAPVQLAALGFIVERTNKQSGCVVAMTMGLGKTLVALTLCFSHLHLAPQADILILTPKPIISHWVDEKNKWGMYGLHFPHFVASDGLNSLEFEQQLLEYERQKNNEKPKAGHVFVINSEYLAGFLRRFRRFTPFLIIVDEGHRVAAKGNKLTESLDRLRCNLRVVLSGTPLQNDASELYRLVGWVNKGVSKVLPPKRFQELANSINQFVEGDDGAFYNAVMAQEYIQDWMRGFVFREMENDLPPLHDYLLVCGSSNVQREYEEKLGLTETAMTALRATEHRPHHLSTHPACYLAFISNCYQSMVSGWTVRAQSNTSRLRTTQLEEIDAMRLEQYAQMIENEQLDAFINVSGKMRVLVDIVLRVQARKEKLIIFSLYVGSQDLIHRTLTALRVCTFTVRGRDSQDRRRRAMHEFSENKDLTVLVLSTKIAAYGLEFTAANHVVLFDSWWNPQADAQAIARAYRRNQRKPVTVYRLISATENKFVLRSQTRKIALFKCIFHKRTTRQALPSELEDCSANETDNERRDFWAKLKATHLVGDTRALLNVYRYQESVRESQ
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Probably also acts as a DNA helicase.  Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis.  Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis.  In contrast to JBP1, it does not specifically bind DNA base J, however it binds chromatin (By similarity).
What are the official names of this protein?
Bifunctional helicase and thymine dioxygenase JBP2, J-binding protein 2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TET family. JBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_CORGL
Sequence: MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQDFIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEANIVDIFKDVLPEDLVKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYRRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDRKDVGEVIINGAVARGEAEPEMLEAVAEEKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: LEUC1_THEMA
Sequence: MGKTLAEKIFSEHVGRDVKAGEIVLARVDIAMAQDGTGPLMINEFRELGFKEVKVPKAFLFIDHASPSPRKELSNSQKMMREFGKEMGVKVFDAGDGISHQILAEKYVKPGDLVAGADSHTCTAGGLGAFGTGMGSTDVAIIFGLGQNWFKVPETIKVVVNGKLQDGVYAKDIILEIARILGSDGATYKALEFHGSCIENMNVEDRLTISNMAVEVGAKAGLMPSDEKTREFLKKMGREEDFRELKADPDAVYETEIEIDATTLEPLVSLPHYVDNVRKVSEVEKEKIKIDQVFIGTCTNGRLQDLEIALKILEKHGKHPDVRLIVGPASRKVYMDALEKGIIKKFVELGAAVIPPGCGPCVGIHMGVLGDGERVLSTQNRNFKGRMGNPNAEIYLASPATAAATAVTGYITDPRRFI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: PRMA_MARMS
Sequence: MPWLQIRINTTPDHVPAFEDTLLDCGAMVVTFEDVHDDPVYEPDLNTTPLWKNTKVTGLFEADADIEHIRPVIEHKAESLGETDIDMKIEIVEDKDWEREWMDNYHPIQFGERLWVCPSWREVPDPNAVTLMLDPGLAFGTGTHPTTALCLQWLDSIDCKDKTIIDYGCGSGILGIAGLLLGANNMVGIDIDPQAVQATEANAERNKIDPSRLEVKLPPYESDLQADIVVANILAGPLAHLAPTISALVKNQGQLALSGILANQAQEVIEAYQEWFTIDSITEKEEWVRIVGTKHA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_ACAM1
Sequence: MSHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MINE_AGARV
Sequence: MGIMDLFKKKSSGNVAKDRLKLVLVSDRANCSSEMMEMMKRDIIEVISRYMDIDAEALDVKITETESDSNNGMVPALVANIPIRDMKHRPDPR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: URE2_MORMO
Sequence: SNTKQPTPLGGVIFA
What are the official names of this protein?
Urease subunit beta, 15 kDa subunit, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_STRGG
Sequence: MPQNPSDRRPAPRDNPGTNAYEPLLSAEVRAALSTGLPVVALESTIIAHGLPRPRNLSVARELEGLVRSAGAVPATVAVLDGRARIGLDGDQLERVAGDPAVRKLGHRDLAPALAAGADGATTVSATAFLAARAGIGVFATGGLGGVHREWAENQDESADLRLLARTGITVVCAGVKSILDVPATLQRLETLGVPVVGYGTGHFPGFYLSSSGEPVDWTVHSPEEVAEVIRAREALGGPVGALIVANPVAERDQLDPVLHDRVLAQALDACRERGISGQGVTPFLLDQLTRRTEGASLEANLAAVRGNVTLAARIAVAAADAR
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: ARC1A_RAT
Sequence: MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRIM
What is the function of this protein?
Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 1A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ARPC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: RS8_SHEB9
Sequence: MSMQDPIADMLTRIRNGQAANHVSVKMPSAKLKVAIAKLLKDEGYIADYAVADEAKPELEVTLKYFQGQPVVETIQRVSRPGLRIYKGKNELPKVMGGLGVAIVSTSKGLMTDRAARLAGMGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: IQCF2_HUMAN
Sequence: MRVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEIINS
What are the official names of this protein?
IQ domain-containing protein F2.
Protein: DCK1_YEAST
Sequence: MSQQDSQRWLPTDRLIYGVLVKSFLPLQRYPELVYENSNYANVYVGAEVYVFEESVDKKWCRAYQCLRPFPEEFISNMNSANDVLPDVKPKVVIFPRKYVHFEAEKAVSTMPFFKAPSAEDFKPLISKECESRSFCDSLYVSSTDDISTGKPRKTPRPPFPFFRYQKRSFKDEMGPILSLISSHVYSMYSIGEFSIYRKMIKLYYDLDTIRFRLSMNLTTEAEKINLIRAATSLRTKIAKFLSSTYRKNKLIANSTPRNPDPYGFEGIFARDIDTGELLSYEIDKLRTLVSSSMLCGLTNNFPTVPVVESDDESSSNGLFGTVRSSILVNLKDLAWDPSISDPKYQDLSICVYLRTKDEVLTESFTMTKSSNMESALDEIPAMLFKNILETIVHKNKVYLVVVLKETIAITTETAPEISSYNISTEESSSHSPFSPFNSSTENKIDHVKKGLAAGVINISPVFKFYNGLSVANKAQRFNLYLYSSDSSDSQNFNSSKDADLGWGGLINKIIKDSSEGVSVNPRAVSLSVTVKEIIGKQEAEKVLSTSLVPIRSIPTYFYDTMFSQAERIYLNLGRVSLYGLPAADTNIENVTVQISCRNKAVKFCKNKLEERSGDWKFVSVRPNESIGESIRIEGVENMNEDETLRVLVYLNGFLMAKSNIHIKKKNEIIEYRKGTVFQIMSSKSVPLIHLELEASYFGRRYNINPAITNFLVLQTKNVEFDQQLKEHYSVTLKQLNNVSFKDLLKHFDTILAHYLLLLESVNEATDKKGPSSSLPNIVFSEFVKFLNLMLTHQENSRYWFNRLYKKVMSKELECPNVAPILIKHMTTIFDRSHSSWTRTGTAICRTILYIIVLAIGSSHSDEMPNFSHFFRSLHKFLMLADEPIMADQILLIESIPSMLETMTNHCKVEDLVRFAIGLFECCQEKEMNQKMYSRPLSVREEEYLNTKFNCLLKLINKKVLQNYLTNTESVDKLRLQFLSKTLEWLLTPYTPGDDKCFHVESLRLVNSVFITIIEDYKFDMLQRNLIRLLPYLCKSFVHLRRYCKKARLMRPRRVFTMLFPREIPCNYIPVDSIVNDEVVVEVLLELAIIICEITKIASSRFPSYQSFSEIINLCDKDTLFQSNFYSRQITNENVYTITKTVFLFFKQDWFPGMKWLGVSALLGRSSLILLSLCKDYIIENNSPSPSKESEKRVDMRLWAEYVKVILLVSNHKSASLTKLAITPRKAVYLISGDLKKISAYILNECWDALATGHYNITYAKKYGLGALSDCQFELFVHNQFLIREIFIFAFHRHIDATRICCKILWGLGLNFWRIFGSLQPAVNACIPELFSAYQIGKLRLNDYELERFVSCLFFMMHVPDSDTFFPACMDFLRDLLGFLHIVNEIYKIPNQEEFDDDRTARHIEMFEYLLEANRPELFHKMIYDLFIHFIQKKDFVQAALSLELLAGTYAWDSNDTLEAISFPPLPEQSSFERKEYLLKESARNFSRGQKPEKALAVYKDLIKAYDEINYDLNGLAFVHDQIAGIYTRLQSIDRLVPTYFKVSFMGFGFPKSLRNKSFVFEGLPFEHITSMHDRLLRSYHGSNIVHSQEEVDMLLMNPPMGKYIHVASVEPCLSISDNYNSSDKKSSINNKVRMYIENRDLRTFSNSRRLPGAKGVTDLWVEEYTYHTMNTFPTLMNRSEIVKVTKSKLSPLENAIRSLQVKIQELYGLENMCNKTLKDHGDVNDLFTELSTNITGTISAPVNGGISQYKAFLEPSTSKQFSTDDLGRLTLAFDELVAVLGRCLTLHAELLPSKDLKPSHDLLVRLFEENFAEEIERYSRTLSEANRSRNNMITARIISHKNPNKKASFSGRDHHTSGSNHSQFVLEHSDSFGPNSLLFGKYLTRTLSHSSTTSSLDKSGIVSGTSSTFLAGSQPNTNTDSQHKHDYSHSG
What is the function of this protein?
Forms a transiant heterodimeric complex with LMO1, that acts as a guanine nucleotide exchange factor exchange factor (GEF) for the small GTPase RHO5 (PubMed:25598154).  DCK1, LMO1 and RHO5 relocate to mitochondria upon oxidative stress and trigger cell death (PubMed:25598154).  The DCK1/LMO1/RHO5 signaling module mediates mitochondrial turnover under nitrogen starvation conditions via mitophagy (PubMed:25598154).  The DCK1/LMO1/RHO5 signaling module plays also a function in cell wall integrity signaling (PubMed:25598154).
What are the official names of this protein?
DOCK-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Quickly relocates to mitochondria under oxidative stress.
Protein: SYE1_DINSH
Sequence: MSPTDASPVVTRFAPSPTGYLHIGGARTALFNWLYARGRGGKFLLRIEDTDKARSTAEATEAIFAGLRWLGLDWDGDAVSQAEGAARHAQVARALQEAGKAYKCFTTQDEIAAFREAARAEGRSTLFRSPWRDADPASHPDAPYVIRIKAPQEGTTVIADQVQGDVRIRNDQLDDMILLRSDGSPVYMLAVVVDDHDMGVTHVIRGDDHLNNAARQMMIYDAMGWDMPVFAHIPLIHGPDGKKLSKRHGALGVEEYQAMGYPAQAMRNYLARLGWSHGDDEFFGDAQAQAWFDLDGIGKSPARLDLKKLDNLSGQHLGVMADEAIVAGAQGYLAATGAPPLTEAQETGLSRAMYCLKDRAKKFPDLLEKAHFILASRPIDPDPKAAKSLDTVSRGILAELTPQLQNASWTRDTLEGVVGGLAEAHGLGLGKLAAPLRAALAGRSATPSVFDMMLVLGRDETLARLSDATSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.