PharMolix/UniProtQA huggingface dataset:
Protein: TGT_FRATH
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPVNSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSPLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: UXUA_STRA5
Sequence: MEMSFRWYGEDDPVTLENIGQIPTMKGIVTAIYDVPVGEVWSRERIQQLKEKVEAAGLKISVIESVPVHEDIKLGRPTRDLLIDNYIQTVKNLAAEGIDTICYNFMPVFDWTRTDLAYQYPDGSTALIFDETVSKKMDPVNGELSLPGWDASYSKEEMKAIMDAYAEIDEEKLWENLTYFIKRIIPEAEAVGVKMAIHPDDPPYSIFGLPRIITGLEAIERFVKLYDSKSNGITLCVGSYASDPQNDVLEISRRAFELDRVNFVHARNIKLGDGKSFKESAHPSEYGSIDMYEVIKLCHEFGFEGAIRPDHGRMIWGETGRPGYGLYDRALGATYVSGLYEAVIKGSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: CH60_STAEP
Sequence: MAKDLKFSEDARQAMLRGVDKLANAVKVTIGPKGRNVVLDKDYTTPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQSMIQEGLKNVTSGANPVGLRQGIDKAVQVAIEALHEISQKVENKNEIAQVGAISAADEEIGRYISEAMDKVGNDGVITIEESNGFNTELEVAEGMQFDRGYQSPYMVTDSDKMIAELERPYILVTDKKISSFQDILPLLEQVVQASRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLELKDASLDMLGTANKVEVTKDHTTVVDGNGDENNIDARVGQIKAQIEETDSECDKEKLQERVAKLAGGVAVIKVGAASDTELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNIYQKVSEIKAEGDVETGVNIVLKALQAPVRQIAENAGLEGSIIVERLKHAEAGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEPENNEQPGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_GLOVI
Sequence: MARNIPLERVRNIGIAAHIDAGKTTTTERILFYSGVIHKIGEVHEGNTVTDWMAQERERGITITAAAITTAWTRRDPENPTQPLPGALEHKINIIDTPGHVDFTIEVERSMRVLDGVITVLCSVGGVQPQTETVWRQANRYNVPRFIFVNKMDRTGANFYKVYSQVRDRLRANAVPIQLPIGAEDTLSGIVDLVGMKAYVYGNDIGTDIRVEEIPADMEELVQEYRAKLIEAVSETDDVLLEKYFGGEELTEAEIKAALRKGTVANTIVPMLCGSAFKNKGVQQMLDAVLDYLPSPLDIPPIKGLLPNGTEVERSADDSQPLSALAFKIMADPYGRLTFVRVYSGILQKGSYALNASKDKKERISRLIVLKADDRIEVDELRAGDLGAVVGLKDTFTGDTLCTEDSPVILESLFIPEPVISVAIEPKTKADLDKLSKALQSLSEEDPTFRVHVDQETNQTIIAGMGELHLEILVDRMLREFKVEANVGAPQVAYRETIRKAVNNVEGLYKRQTGGKGQYGHVVINLEPGEPGTGFEFVSKIVGGVVPKEYIGPAEQGMKERCESGVIAGYPLIDVKVTMVDGSYHDVDSSEMAFKIAGSLALREAAQKAQPVLLEPMMKVEVEVSGDFLGDVMGDLNARRGQIESMDNEGGVSKVTSRVPLAEMFGYATDIRSKTQGRGTFSMEFSHYEEVPRNVAETIIAKNKGNA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_THISH
Sequence: MLTFTKRCDDHGKTPDHSLSLPFETRQKSRFRAQFEDGTPVGVVLDRGLILRHGDVLESDEGVRVRIEAAPEPVSQVRGTDPLLLARACYHLGNRHVVLQIDADGLRYLHDHVLDDMVRGLGLTVGFTHAPFEPEAGAYAGGHAHGHGGHGHHHAHGHEH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_SHEDO
Sequence: MKFIDEASIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVFLQADENYNTLIDYRFERFHMAERGSNGRGRDCTGHGGVDLILKVPVGTRAVDDETQELIGDLTAHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLRLELLLLADVGLLGMPNAGKSTFIRAVSRATPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGASDGAGLGIRFLKHLERCRVLLHILDIDPIDGSSPAEAAKAIVAELEKYSPKLAAKPRWLVFNKTDLMLEEDLQERVDAIVAEMDWQGDVYTMSAFNRIGTKELSLKLLDYIASLPPIDDSIDPDSEVEFKWDNYHEANTDSVNEDYNDDFDDDFDDDDYDVEVIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BURA4
Sequence: MTLNSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADLSKNRINDDTLRLLVQLAREAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPHAPFHAQISAERAKMATFARAVRSGAWTGYTGKRIRHVINIGIGGSDLGPKMVTHALHHVASPDISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVARGCPEAALAKHFVGVSANPAEVVKFGIDADNVFEMWDWVGGRYSLWSAVGLSIMIAIGPEQFDELLAGANDMDRHFRQAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLDEARKVAGPGKEALAPHLTFPGNRPTTTLLVDALTPRTLGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESVDPAKHDSSTTALIERARAALKR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_STRPF
Sequence: MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDTNQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GCH1_DEHMB
Sequence: MFDEQAIKQSVQNILVAIGEDPDREGLKETPRRVAQMYTELFSGMNQDPAEVLRVGYELGHREMVIIKDIPFYSMCEHHLLPFSGVVHIGYIPNIDGRVVGISKLARVVEIYAKRPQIQERMATQIADAIMDGLKCDGVAVVIEAEHMCMVMRGIKKPGSRVITSALRGSFHKSPAARAEFLSLIQHKG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: COAX_CARHZ
Sequence: MFLAIDIGNTNIVLGIYDKGKLIKTWRMAADRNKTVDEYAVLIHNFFSFINLSFKDIEGIGIASVVPPLTPIFEQLCYNYFKVKPLVIGPGVRTGLKIKFENPREVGADRIVNAVAGYHIYGGPLIVVDFGTATTFDAINDKGEYIGGAISPGIGISTEALFARASKLPRIELVKPLSVIGKNTVSAMQAGIIYGFIGQVDEICARMKKELGGAAKVIATGGLAELIATDSRQIEKVDQNLTLEGIRLIYERNQAGN
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET2_KOMPG
Sequence: MSELTEAEKRQLLREKRKAKLSQGGGLDRLKKITGENNSKLSTDVPTKEPTADATTTATELPTQGLETRINAHDDPVSEIPDPLNEGFDGKEPDLDQLIASMFNKSAGHENPNSEEQGVPELMRRFSSILQGGDSGAAGLGAEAGGINPLDLLNSLGGSNIGKAQEEYGSTPEEIEFNKKSIAYKKHQNEVLKAKILVVRLVLILSLLFVYGRDFSLSLFTQTYAPNGSSFMRVFLTLELIFQTSLFFFISKNKNFTDDSLISKLLNIGGAFIPATYRNLLQTASKYQVLLSMFLFDLSIVVVVFAIRAAFNF
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TRI11_FUSSP
Sequence: MFQYSLWPLLALSGGTGLAYLVVVVVYNLFFHPLRNFPGPWLNSITQVPHTLLMLCGLPHKKHLALHMKYGPVVRIGPNMLSFNHPDAMKDVRGHRKSGEPEHGKDPISVQSNGDNIVGSDRENHTRFRRALAYGFSAQAMLEQEPTFKAYVNQLFQRLHEQSSGGTKPVDISKWYTFTTFDMIGDLAFGESFSCLDNSTYHPWVSLAFESLKSLAFLAEIGRYPRIAPYLGLLVPRGLLTKFAENKELASMKVRKRLDTETDRPDFVGKITQGLKSKGTSMEFNELASNASVLIVAGSETTATLLSAAVYFLCAHPRTLDLLTKEVRSTYTQAHDIDLVSTQGLRYMQAVLDEALRMYPPVAGGGSPRKIAKGGSFVAGHFVPENTLVENDMWAMHYDPKYFTQPHDFIPERWLGDVRFANDRLDAVKPFSIGPRNCIGMNLAYAEMRMMLARTVWEFDIRLSEGSRNWYEESRVYLAWNKPPLNVYLIPR
What is the function of this protein?
Trichothecene C-15 hydroxylase; part of the core gene cluster that mediates the biosynthesis of trichothecenes, a very large family of chemically related bicyclic sesquiterpene compounds acting as mycotoxins, including T2-toxin (PubMed:11352533, PubMed:9435078).  The biosynthesis of trichothecenes begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:3800398).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4 (PubMed:7651333).  TRI4 controls the addition of four oxygens at C-2, C-3, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichotriol (PubMed:16917519).  Isotrichotriol then undergoes a non-enzymatic isomerization and cyclization to form isotrichodermol (PubMed:2317042).  During this process, the oxygen at the C-2 position becomes the pyran ring oxygen and the hydroxyl group at C-11 is lost (PubMed:2317042).  More complex type A trichothecenes are built by modifying isotrichodermol through a series of paired hydroxylation and acetylation or acylation steps (PubMed:11352533).  Isotrichodermol is converted to isotrichodermin by the acetyltransferase TRI101 (PubMed:10583973).  TRI101 encodes a C-3 transacetylase that acts as a self-protection or resistance factor during biosynthesis and that the presence of a free C-3 hydroxyl group is a key component of Fusarium trichothecene phytotoxicity (PubMed:10583973).  A second hydroxyl group is added to C-15 by the trichothecene C-15 hydroxylase TRI11, producing 15-decalonectrin, which is then acetylated by TRI3, producing calonectrin (PubMed:9435078, PubMed:8593041).  A third hydroxyl group is added at C-4 by the cytochrome P450 monooxygenase TRI13, converting calonectrin to 3,15-diacetoxyspirpenol, which is subsequently acetylated by the acetyltransferase TRI7 (PubMed:12135578, PubMed:11352533).  A fourth hydroxyl group is added to C-8 by the cytochrome P450 monooxygenase TRI1, followed by the addition of an isovaleryl moiety by TRI16 (PubMed:12620849, PubMed:14532047).  Finally, the acetyl group is removed from the C-3 position by the trichothecene C-3 esterase TRI8 to produce T-2 toxin (PubMed:12039755).
What are the official names of this protein?
Trichothecene C-15 hydroxylase, Core trichothecene cluster (CTC) protein 11, Cytochrome P450 monooxygenase TRI11.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LPXK_BACFR
Sequence: MEENSIKIHKWLYPASWLYGAGVALRNKLFDWGKLQSKSFNVPIICIGNIAVGGTGKTPHTEYLIKLLHDEFQVAVLSRGYKRHTKGFVLSTAESDARSIGDEPYQIQSKFSDIRVAVDEDRCHGIERLLTLKEPPVEVILLDDAFQHRYVKAGLNILLTDYHRLFCDDTLMPAGRLRESAQGKNRAQIVIVTKCPPDIKPIDYNIITKRLNLFPYQQLYFSSFRYGNLRAVFPDCATVQERKLSSLQTEEQILLITGIASPDTIIRELEIHTRNIDLLAFSDHHNFSQRDLAQIKERFGKLRKGQRLIVTTEKDATRLICHQELDEGLKPFIYALPIEVEILQNQQDNFNQHIIGYVRENTRNGSLPERKDAHKS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: TRM5_DROPS
Sequence: MNCSELLPPASVRGMRELQRAEFQKRVQVPQLRVPEQQVQRVIPLVKKFLLKMEHMHPVRAVDKSREILLHPMPIKAWESLPTEDLQKQQVTQENFSFVELELNYENWSANEILKSVLPEEEEGMTSYSRIGHIVHLNLRDHLLPYKQLIGEVLRDKLPNCRTVVNKASSIDNTYRNFQLELICGEAEYQVETKENGIPFEFDFSKVYWNPRLSTEHERIVKLLQPGDVLYDVFAGVGPFSVPAAKKRCHVLANDLNPVSFHWLQHNAKRNKCLSNIKMSNKDGREFILKELRADLLQRLRLTDTSSYATHITMNLPAMAVEFLDAFRGLYTDNELADISDAVVFPTVHVYSFAKGENTKALVRAQVEQNLASTLDEKQLQGISFVRNVAPNKDMYRVSFKLTRHLLTTSKEAEANNVRKRCAEDEKVDPEVAATKVKCV
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: SSEL_SALTY
Sequence: MNICVNSLYRLSIPQFHSLYTEEVSDEALTLLFSAVENGDQNCIDLLCNLALRNDDLGHRVEKFLFDLFSGKRTGSSDIDKKINQACLVLHQIANNDITKDNTEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCGARMLSSDELAAATQGLVQESPLLSVNYPIGLIHPTTKENILSTQLLEKIAQSGLSHNEVFLVNTGDHWLLCLFYKLAEKIKCLIFNTYYDLNENTKQEIIEAAKIAGISESDEVNFIEMNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQALFNTQTRRQIYEYSLQ
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells.  Specifically hydrolyzes mono- and polyubiquitin substrates in vitro with a preference for 'Lys-63'-linked ubiquitin chains, suggesting that it interferes with a signaling pathway rather than inhibiting proteasomal-dependent degradation of its targets.  Does not possess desumoylating activity.  Is required for the Salmonella-induced delayed cytotoxicity in macrophages and full virulence.  Is not required for intracellular bacterial replication.
What are the official names of this protein?
Deubiquitinase SseL, Deubiquitinating enzyme, DUB, Deubiquitinating protease, Salmonella secreted effector L.
What is the protein family that this protein belongs to?
Belongs to the peptidase C79 family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. In phagocytic cells localizes to the Salmonella-containing vacuole (SCV). In epithelial cells localizes to the Salmonella- containing vacuole (SCV) and to the Salmonella-induced filaments (Sifs), which are tubular membrane extensions from the SCV that are formed at late stages of infection.
Protein: YCF3_LIRTU
Sequence: MPRSRINGNFIDKTSSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEATRPEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWSDQAAEYWKQAIALTPGNYIEAHNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YR365_MIMIV
Sequence: MNLLNMFNGYKKIPVEYFAQEESMEQLKDINTKIDNSEKKISLENFIDKCEKSDPISENDFLDYPEHIVRSYVKHNVESFIDNNKTNLLNKLLILFPESVFYMASCEKFITIFSKVKDNINGLLINSDKQTFLHKILTLEDSMIILESNIDLNVNQIDINGDTFVSNYYDNIDALYKKNNNTNYENHHTSSKKMIKFVELLVKKNYNVNRVDNINRSIINLCFRVNVNKSIIFSYKNMAYKQQYFFIDYYCLYNLFQMKKLIPL
What are the official names of this protein?
Uncharacterized protein R365.
Protein: RB27B_RAT
Sequence: MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLLDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPDTVNGVNSGKVDGEKPAEKKCAC
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (By similarity).  Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).  May be involved in targeting uroplakins to urothelial apical membranes.
What are the official names of this protein?
Ras-related protein Rab-27B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Late endosome.
Protein: RPOB_HELMI
Sequence: MVYPVQCGPRERWTFARIQEVMDMPNLIEIQQNSYRWFLEEGLREMFRDISPIQDFTGNLILEFIDYALGEPKYSVEECKERDVTFAAPLRVKVRLINKETGEVKEQEVFMGDFPLMTDKGTFIINGAERVIVSQLVRSPGVYYNEAIDPPSGKKLFGATIIPNRGAWLEFETDINDNIFVRIDRTRKLPATVLIRALGYSNNAQVQELFDGDERIRITLERDNTENTEEALVEIYKRLRPGEPPTVDSARSLLETLFFDPKRYDLAKVGRYKINKRLGISVEREVRHLTKDDIIAAIRELLKLMQGDGRADDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMTIQDVEVITPQVLINIRPVVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLIGSLSTFARINEYGFIETPYRKVDKERGVVTDQIDYLTADEEDKYIVAQANAPLDEEGRFKEKRVNARHGHDILVVPVEKVDYMDVSPKQVVSIATALIPFLEHDDANRALMGANMQRQAVPLLRTDAPYVGTGMEFKAAYDSGVCAIARKAGYVERVTGDEILIRCDDGTTEHHKLLKFLRSNQGTCINQKPICHKGQRIEAGQIIADGPSTDQGELALGRNVLVAFMTWEGYNYEDAILVNEKLVKEDYFTSIHIEEYECDSRDTKLGPEEITRDIPNVGEEVLKDLDDRGIIRVGAEVRPGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGKIVDVKVFSRENGDELAPGVNQLVRVYIAQKRKISEGDKMAGRHGNKGVISRIMPEADMPYLPDGTPVEIVLNPLGVPSRMNIGQILETHLGWASKHMDRGVLIEGKPSGEKGIRVATPVFDGATEDDIFEFLTKAGLPKANEIALTDTRTESLRESMAAVPLGKSILYDGRTGEPFDNPITVGYMYMLKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQSLGLDVKILSEDEREIEIKEVEEDVAETAKELGIDIQGEDRSERAGEPASPDEMDDEEEIDYAAGFLQDALEELEED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CFI_VERHY
Sequence: MIILPSITEVQVESVVFPPAVKPPGSDKTFFLGGAGVRGLEIEGKFIKFTAIGVYLENDAVTSLAAKWKGKTAEEVADSGDFFAEIVTGPFEKFTKVTTILPLTGQQYSEKVVENCVAYWKAIGKFTDAEDEATKKFLQVFKNEMFHPGASILFTQSPQGSLTISFSKDGSIPEKENAIIENKQLSEAVLESIIGKKGVSPSAKQSLAARLSDLLKQCESTT
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: EFG1P_PHANO
Sequence: MSQKRKHDDTPGDASSASKTFKKHRPFKPGQNHQQTKHHRRPNLSHDDENGRSTNALKSRIRDLKRFLTHMDSVEKHKMSAGARQERERELEACEHELAEKLNASREAEYRKKMIGKYHQVRFFDRQKGTRILKRLKKELSALEDDSKKTALQQRIHNAEVDVNYAIYYPLMKPYSSLYPKSKNKKSSDSEEAEDTGEDSKNSAEVDGPKGDVNMWKAIEEAMQDGTLEKLRYSKDAVPAEPPKKSKKPKAKDSKKEKSVSKTSHDASASHNYAVQDQDEDSDGGFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GN_MUHVS
Sequence: MACGKTESGDDSGRFGRTGAGMFGFIMPGFVGIFRLSFFLLLSFAMASGSSSPASVPVSVAASVPDTTVNKIVISDGSEAHNINEFYDVKCHSHFYGLSVSSFASIWMMVNAIVFICAFGVFMRHWCYKAFTSDTAKGY
What is the function of this protein?
Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity.  Also plays a critical role in virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein N.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein N family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=When coexpressed with gM, localizes in the host trans-Golgi network.