PharMolix/UniProtQA huggingface dataset:
Protein: NUD4B_HUMAN
Sequence: MMKFKPNQTRTYDREGFKKRAACLCFRSEQEDEVLLVSSSRYPDQWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGIFEQNQDRKHRTYVYVLTVTEILEDWEDSVNIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGCSPANGNSTVPSLPDNNALFVTAAQTSGLPSSVR
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction.  Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A.  The major reaction products are ADP and p4a from Ap6A.  Also able to hydrolyze 5-phosphoribose 1-diphosphate.  Does not play a role in U8 snoRNA decapping activity.  Binds U8 snoRNA.
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B, DIPP-2B, Nucleoside diphosphate-linked moiety X motif 4B, Nudix motif 4B, Nudix hydrolase 4B.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLA1_MOUSE
Sequence: MRRTPAAERLSELGFPPRRGRQEPPFPLGVTRGWGGWPIEKRREGPRPVPFSERSPEDGREQPAHGSGILWRVRTRLSLCRDPEPPPPPPPLCLLRVSLLCALRAGGRGSRWGEDGAGLLLLPPAGASGSLKAERSSSTPYAGRMLENSGCKALKEGVLEKRSDGLLQLWKKKCCILTEEGLLLIPPKQLQQQQQQQQPGQGTAEPSQPSGPTVASLEPPVKLKELHFSNMKTVDCVERKGKYMYFTVVMTEGKEIDFRCPQDQGWNAEITLQMVQYKNRQAILAVKSTRQKQQHLVQQQPPQTQQIQPQPQPQIQPQPQPQIQPQPQPQPQPQPQPQPQPQPQQLHSYPHPHPHPYSHPHQHPHPHPHPHPHPHPHPYQLQHAHQPLHSQPQGHRLLRSTSNSA
What is the function of this protein?
Seems to be involved in regulation of apoptosis.  May be involved in detachment-mediated programmed cell death.  May mediate apoptosis during neuronal development.  May be involved in regulation of anti-apoptotic effects of IGF1.  Required for TCR-induced apoptosis and expression of TNFRSF6/FAS in a T-cell hybridoma cell line.  May be involved in translational regulation.
What are the official names of this protein?
Pleckstrin homology-like domain family A member 1, Proline- and glutamine-rich protein, PQ-rich protein, PQR protein, T-cell death-associated gene 51 protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles.
Protein: ETF2_VARV
Sequence: MRYIVSPQLVLQVGKGQEVERALYLTPYDYIDEKSPIYYFLRSHLNIQQPEIVKRHILLTLRMTQLKGYLGNLLDIKDDIIIYSHKNNLEYSYVDNTIFNPFVYTQKKTLLKNDSFLYNVYPGACDFLVIWVARACDTSIPEFGSYEDVDNNIIKFETMLMDVFPQLDLDITVESKFNNIFRTNLKLTGLKKIIQRVQDLDINYKSLLSRYDEHFINMTGNHFILNDEQLNLSIWDLDGTLALSSDGDTVMINNVKLFTDLVSDIDTQMERIKGDITYKVHLATPINSRIKLDIETSFIFIETATNNILLSSDKKISIILAKNHISIKVKNHIPNIEKYFTFLVIAINAMFNSVQKSADFTKVETVYWSRICQNTKNKNRKPVIINYLDPGMKKISNNFYRSDEKEVFINDNDIMFTCMDPLGKYNKVGFLNIFHDMRKYCIPCCFLHDQSHRSTFSSCVHQIDVEKKIVSPYILNFGKVVTESKMSFLPIIFDAFLNDGMTANMEQDNKRLKETSGYHIVRCCTGNDIVRLRTTSNIIQFVNEDKNILIVNDMVYFPMNASDIGKKIHILIQEIVHEVMIVKKKESSDKIDFFPPNYKLLKDLFPKQTIQTPIQSDAGMVLTTDGFYIDGKLFNEDLSSKYVTFTKNVITSDAVAKYFSPLFKYVISEAKDRFIKTWMINIMIHMNVDPNNIIPTLEKYYPNFGRVQIN
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa RAP94/OPG109 to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters.
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit, VETF A7 subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RS8_CAMJE
Sequence: MINDIISDSLTRIRNAGMRKLETTKLLHSKVVEALVGIFQAKGYIESFNVIEEDKKKFINVVLKYDEKGKSVINELKRISKPGRRVYKGKDEIKRFKNGYGTIVVSTSHGVLANDEAYKAGVGGEILCTIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PRSA_STRP7
Sequence: MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CHRA_PSEAI
Sequence: MSVANEESYRPSKATDATTEAVPPPMSYPQLFARFLKFGLLAWGGPVAQIDMLRRELVDEERWISSKRFNKLLAVMQVLPGPEAHEICVHLGIRAKGRLGGVLAGLGFMLPGFLLMFALSWLYFQIEFVGTALGAAFLGVQAAVIALIVRAVHRIGEHILLDRWLWVIAIVCALAAIGRVDFWITLPAGGLVYALLVLNHRASALLVTLAAVALAAAVALWAAPTAKLVEAVVQGQASVLLIFASGLKAGLLTFGGAYTAIPFVRNDAVGRGWMTDGQFLDGLALSGVLPAPLIIFATFVGYVAGGPIGAVAMTVGVFLPAFAFSLIFYDRLEAVVENKRLHAFLDGVAAGVVGLIGATTIDLAQVTAERVPSLTVGMSIFAAGLAFLYAWKNKLNVVVVILAAGLAGWLVFPNQG
What is the function of this protein?
This protein reduces chromate accumulation and is essential for chromate resistance.
What are the official names of this protein?
Chromate transport protein.
What is the protein family that this protein belongs to?
Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGR2_BACC1
Sequence: MNKGQRHIKIREIIANKEIETQDELVDILRNEGFNVTQATVSRDIKELHLVKVPLHDGRYKYSLPADQRFNPLQKLKRNLVDSFVKLDTAGHMLVLKTLPGNAHSLGALIDHLEWDEIIGTICGDDTCLIICRTPEDTGVVSDRFLNML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AJUBA_RAT
Sequence: MERLGEKASRLLEKLRLSDSGSAKFGRRKGEASRSGSDGTPGAGKGRLSGLGGPRKSGHRGANGGPGDEALEPAREQGPLDAERNARGSFEAQRFEGSFPGGPPPTRALPLPLSSPPDFRLETTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGASGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGLPLTTAPSGYSSGGVPSAYPELHAALDRLCAHRPVGFGCQESRHSYPPALGSPGALTGAVVGTAGPLERRGTQPGRHSVTGYGDCAAGARYQDELTALLRLTVATGGREAGARGEPLGIEPSGLEESPGSFVPEASRSRIREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLSARQPPTNYI
What is the function of this protein?
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.  Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton.  May be involved in signal transduction from cell adhesion sites to the nucleus.  Plays an important role in regulation of the kinase activity of AURKA for mitotic commitment.  Also a component of the IL-1 signaling pathway modulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex.  Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes.  Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription.  Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A.  Positively regulates microRNA (miRNA)-mediated gene silencing.  Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1 (By similarity).
What are the official names of this protein?
LIM domain-containing protein ajuba.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane. Cell junction. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, P-body. Note=Shuttles between the cytoplasm and the nucleus (By similarity). Localizes on centrosomes during G2-M phase (By similarity). Colocalizes with GFI1 in the nucleus (By similarity). Preferentially colocalizes with cadherin-adhesive complexes at sites of cell-cell contacts.
Protein: MOAA_BACLD
Sequence: MNTNSEQVLDQKSRPLRDLRISVTDRCNLRCTYCMPAEIFGQDYPFLPKGELLSFEELERLAKLFVHQFGVEKIRLTGGEPLMRKDMPELVGKLAGIKGIRDIAMTTNGVLLPVYADKLKKAGLKRVTVSLDSLDDERFKSINGRGVSVSKVLAGIEAAKKAGLGVKINMVVQKGVNEKDILPMARYFKEKGHILRFIEFMDVGNTNEWNRQSVVAKADIIRIINEDMPIEPIDPNYEGEVAKRYRYLDGSGEIGFISSVSDAFCTTCNRARLSAKGELFTCLFASSGFDLRTLIRSGQTDQELAEAIGTVWRNRDDQYSLDRALAKAVPRKKVEMSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: MRAY_XANAC
Sequence: MLLELARWLQQLESLFGLFNYLTFRGILAALTALFLSLWMGPAVIRKLAQFKGGQPIRQDGPQTHFSKAGTPTMGGSLILLTVTLSVLLWGDLRNRYVWLVLAVMICFGAIGWYDDWIKIVKRDPNGLKSRWKYLLQSIFGLAAGLFLYYTADVPAAITFYIPMFKSIALPLAGVSFVVIAYFWIVGFSNAVNLTDGLDGLAIMPTVLVACALGVFAYASGNVVFAEYLKIPLIPGAGELIIICSAIAGAGLGFLWFNTYPAMVFMGDIGALSLGAVLGTIAVIVRQEMVLVIMGGVFVIETLSVMIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPMA_CHESB
Sequence: MSGTLILVRHGQSEWNLKNLFTGWRDPGLSELGHEEATSAGRKIKDRGLRPDIAFTSVLSRAKVTNTHILEVLGLPALETIEDVALNERDYGDLSGLNKDDARKKWGEEQVHIWRRSYDIPPPGGESLRDTGARVWPYYLREILPQVLRGKTVLVSAHGNSLRSLAMVLDGLSGEEIVKMEIATGVPIVYRLNPDSTVASKEILEG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RNPA_SHEB2
Sequence: MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ANR26_HUMAN
Sequence: MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDESSEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEEPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPLGSTDESNLNQDLVWKASREYVQVLKKNYMI
What is the function of this protein?
Acts as a regulator of adipogenesis.  Involved in the regulation of the feeding behavior.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 26.
Protein: SYV_BLOFL
Sequence: MIINTIDKIYNPKNIEESIYNFWEKSNYFEPDIINNYKKNYCIMMPPPNITGGLHLGHAFQQTIMDILVRYQRMNGKNVLWASGLDHAGIATQILIEKNFYNKKNSIKDNHDPHSLIKEVWLWKEKSEKFINYQIKRLGHSVSWKNKHFTMDPEISLAVKEAFIQLYTNNLIYKGKQLVNWDSKLQTAISDLEVSHKQKSDFIWYIQYQLEYNTSHINNQKKNADYLTIATTRPETILGDVAIAVNPEDPRYSHLIGKYVFTPITNRRIPIISDKFVNINKGTGCVKITPAHDFNDYIIGKKYKLPMINIFSTYKTILTIPEISNNQGQPYIQSNDQYHIPKMFHNLDYKDARKKIIEECKRLKILEDIKTHQLTVPINNRTGTIIEPMLTDQWFIKTKFLAKQAINAVTNEKIKFIPKNYTNIYLQWMNEIQDWCISRQIWWGHRIPVWYDNNNTIYVGHCEKDIRIKNQLNKDIQLSQDNNVLDTWFSSSLWTFSSLGWPKNNTLLKMFHPTNIIISGFDIIFFWIARMIMMTMYLVKDQNNNAQIPFKKIYITGLMRDKFGQKMSKSKGNGIDPIDIIDGISKKKLLKKQLKENSQSKSISSIIKYINTQFPNGIKPYGADTLRLTLTALASSGQDIHWDMHKLESYHNFCNKLWNVSKFVITHTDNYHYDIDTKNKKIFSLSDRWITSKLHQTIQKFSQALNDYRFDHTVNILYEFIWHQFCDWYIEFTKPILYHSTNTLQLISTRYTLITSLESILRLSHPIIPFITEKIWQKIHSIVTTNNKHTIMLQSFPKYDSNYIDLESISDIEWIQNLIAEIRMIRTYTGISYKIPLDIGFYNTSNHIKECISENYHILTKILQLQTINFLEKNDISNNRYFKIPIKESELIIFIPNIFDKKTAIHKFNKEIKLINYKIHLLEQKMNNTNYSLNLQHSFKKSQEKLNHYNKTKNKLLNQYFIVKNL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOR1B_MOUSE
Sequence: MRRIGAFGGSTALWALLAAHVAGAFEPVSVGIAIGAVSALTGYLSYTDFYCRFTECCHEERPLNTSALKLDLEEKLFGQHLATEVILKALTGFRNNKNSKKPLTLSLHGWAGTGKNFISQIVAENLYPKGLKSNFVHLFVSTLHFPHEQKIKVYQDQLQKWIRGNVSACGSSVFIFDEMDKLHPGIIDAIKPFLDYYEQVDGISYRRAIFIFLSNAGGDLITKTALDFWRAGRKREEIQLKDLEPVLSVGVFNNKHSGLWHSGLIDKNLIDYFIPFLPLEYKHVKMCVRAEMRARGAAVDEDVVTSVADEMTFFPKDEKIYSDKGCKTVQSRLDFH
What is the function of this protein?
May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins.  Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity.  May have a redundant function with TOR1A in non-neural tissues.
What are the official names of this protein?
Torsin-1B, Torsin ATPase-1B, Torsin family 1 member B.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Nucleus membrane.
Protein: EFTU2_WOLPM
Sequence: MTAIVEAFGKPHVNVGTIGHVDHGKTTLTAAITKHYGNFVAYDQIDKAPEERKRGITIATAHVEYQTEKRHYAHVDCPGHADYVKNMIVGAAQMDAAILVVSGVDGPMPQTREHILLAKQVGVGYIVVYINKADVADADMIDLVEMEVRELLSKYGFPGDEVPVVVGSALKALEDDSSEYGKKSIDKLMEKLDEYVAVPPRPVDLPFLLPIEDVFSISGRGTVVTGRIEKGEIKTGEEIEIIGLKATQKTICTGVEMFKKLLDKGSAGLNVGILLRGTKREEVERGQVLAKPGTITPHRKFKAEVYILKKEEGGRHTPFFANYQPQFYLRTTDVTGSIKLLDGKEMVMPGDNVSVEVELQVPIAMDKGLRFAIREGGRTVGSGVVSEILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH4_MOUSE
Sequence: MQLLLALLALAYVAPSTEDSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKRQVFKSHAPGQLLSLPLPTLLVPTLTCLVANFLQ
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH.  May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis.  It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
What are the official names of this protein?
Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ARGB_SHEPC
Sequence: MSTNNSVLVLKVGGALLQCEMGMARLMDTAAAMLANGQKVLMVHGGGCLVDEQLAANGMETVKLEGLRVTPPEQMPIIAGALAGTSNKILQGAATKAGIVSVGMSLADGNTVSAKIKDERLGLVGEVTPKDGTYLKFILEQGWMPICSSIAMMDDGQMLNVNADQAATALAKLVGGKLVLLSDVSGVLDGKGQLIHSLNGKQIADLVKQGVIEKGMKVKVEAALEVAQWMGQAVQVASWRDASQLIALAKGEAVGTQIQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_STRCO
Sequence: MAQLKITQVKSYIGSKQNHRDTLRSLGLKGINTQVVKEDRPEFRGMVHTVRHLVTVEEVD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NDK_CHLAD
Sequence: MERALLILKPDAVQRGLIGAIISRFEQRGLKFQGLKLMQVDEALARRHYAEHEGKSFFEGLVKYITSAPVVVAVVAGKPGTVELVRTMVGATNPAKAAPGTIRGDFGVDIGRNLIHASDSPESGERETAIFFQPHELIGDWNRTLDGWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_VESOH
Sequence: MPIITLPDGTKKIFEQVVSVEQVAKSMGLVKAALAGEVDGELVSTSFLIKTDANLTIITANDDQGLEIIRHSTAHLLAQATQMLYPDAQVTIGPVIDNGFYYDFAYKNGFLEGDLIKIEKNMHKLVKQNLKIEKFEMSRDETLQFFKDKGEYYKVKIIESISTDQILSLYKQGDFIDLCRGPHVPSTAKLKNFKLMKLAGAYWRGDSSNEMLQRVYGTAWGNEQDLKVYLHKLEEVARRDHRKIGKTQDLFHIQEETPGMVFWHAKGWILYQLVEQYMRGIFRDNGYQEVHTPQLIDKSLWEKSGHWDKFGDVMFTTTSGDRDYAVKPMNCPAHIQIYNQGLKSYRNLPLRLAEFGSCHRNEPSGTLHGIMRVRNFVQDDGHIFCTPEQIQDEVSTFIDLTFNVYKYFGFEKINIKLSTRPKKRVGSDEVWDKSEIALVEALNAKNIVWELQEGEGAFYGPKIEFILKDCLDRQWQCGTLQVDFSMPKRLGAQFIDENSVKKTPVILHRAIMGSLERFLGILIEHYEGAYPCWLSPIQAVIINISEKHAKFIVDIVKKLKKQGLRVISDLRNEKVSFKIREHSLQRYPYILVVGDREMEKGQVSVRQRGGKDLGAMSVGTFIKKVNQETLLKNQIK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP7F_ASHGO
Sequence: MSIPFGLDFGNNSSVLAVARNRGIDIVVNEVSNRSTPSLVGFGQKNRFLGEAGKNKQTSNIKNTVDNLKRIVGLDHAHSDFEEEAKFFSSKLVKMEDGKIGAQVRFAGEQQVFSATQIAAMFMNRAKTIVQDETKGKVTDVALAVPAWYNEAQRYAAADAARIAGLNPVRVVNDVTAAAVSYGVFKTDLPEGEEKPRRVAFVDIGHSSYTCSIGSFKKGELKILGTAYDKHFGGRNFDRAITEHFAEEFKGKYKIDIRENAKAYNRVMTAAEKLKKVLSANTAAPFNIESVMNDVDVSSQLTREELEELVAPLLKRVTEPVTKALAQAKLTPEDIDFVEIIGGTTRIPCLKNAISAAFNKPLSTTLNQDEAIAKGAAFICAIHSPTLKVRPFKFEDIHEYSVSYHWDQQVEDEDHLEVFPAGSSYPSTKLITLHRTGDFTMTAKYTNPEVLPAGMPEEIAKWEITGVKVPEGETSVPVKLKLRCDPSGFHIIENAYTVEDIKVKEQIPPAADAPEDAEPEYKEVTKTVKKDTLQIVAHTFALEEAVLNELIEKENELAAQDKLVAETEDRKNTLEEYVYTLRGKLDEEYAAFASDEEKTKLKDMLAKAEEWLYDEGYDSTKAKYIAKYEELASLGNVIRGRYMAKEEEKRQALRAKQEAAQMAEMAEKLAAQRAAEQKAQESKAESDKDAEGDIDLD
What are the official names of this protein?
Heat shock protein homolog SSE1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.