PharMolix/UniProtQA huggingface dataset:
Protein: RL6_PROM9
Sequence: MSRIGKTPVLIPEKVTVDLDGLIVTVKGPKGELKRLMPEGVSFDKKDNTVVVSPTTNKIHSRQRHGLCRALIANMVEGVTQGFSKKLEIVGVGSRAQVKGKNLVVSAGYSHPVEMIPPDGITYKVESNTNVTVSGIDKEIVGNEAAKIRSIRPPEPYKGKGIKYHDERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: UVRC_MYCTA
Sequence: MPDPATYRPAPGSIPVEPGVYRFRDQHGRVIYVGKAKSLRSRLTSYFADVASLAPRTRQLVTTAAKVEWTVVGTEVEALQLEYTWIKEFDPRFNVRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHRQIDRPCLLGYIDKCSAPCIGRVDAAQHRQIVADFCDFLSGKTDRFARALEQQMNAAAEQLDFERAARLRDDLSALKRAMEKQAVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWIVEKPGEPGDSGIQLVEQFLTQFYGDQAALDDAADESANPVPREVLVPCLPSNAEELASWLSGLRGSRVVLRVPRRGDKRALAETVHRNAEDALQQHKLKRASDFNARSAALQSIQDSLGLADAPLRIECVDVSHVQGTDVVGSLVVFEDGLPRKSDYRHFGIREAAGQGRSDDVACIAEVTRRRFLRHLRDQSDPDLLSPERKSRRFAYPPNLYVVDGGAPQVNAASAVIDELGVTDVAVIGLAKRLEEVWVPSEPDPIIMPRNSEGLYLLQRVRDEAHRFAITYHRSKRSTRMTASALDSVPGLGEHRRKALVTHFGSIARLKEATVDEITAVPGIGVATATAVHDALRPDSSGAAR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1IA1_LOXIN
Sequence: MLPYIALILVCWSVLSQAAQTDVEGRADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQATANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (PubMed:15234562, PubMed:9790962).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  It induces complement-dependent hemolysis, dermonecrosis, vascular permeability and platelet aggregation (PubMed:15234562, PubMed:9790962).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaIA2ai, LiP2, P2, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 2, SMD 2, SMase D 2, Sphingomyelinase D 2.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KUP3_BRADU
Sequence: MTMGALGVVYGDIGTSPLYALKEAAKAAAHGATVTPDAVLGVASLILWALLLIISLKYALLILRADNRGEGGIVALLALLHARNAQPGTWRSHLLVVGLVGAALLYGDGAITPAISVLSAIEGLKVDAPSLAPAVVPVTVVILVGLFMMQKQGTGFIGRIFGPVMLAWFAVLAALGIHGIVKAPAVLAALSPLYAVEFLIHQDFHVSFAILGAAFLAVTGGEAMYADMGHFGRLPIRLAWFAICLPALVLNYFGQAALLITDPAMIENPFFQLCPDALHYPLVAFSAVATVIASQAIISGVFSLTQQSIQLGFLPRMQIRHTTSDAIGQIYVPLVNWLLAAATLGAVLSFGSSDALAGAYGIAVSLLMAITTLLAALVAIQWGYSPWLVVAVNGAFFVIDVIFFSANSIKLFEGGWFPLLLAALVAFMMLTWRSGVKLVEAARAKLRQPEEDLIETAVNKCSARLPGTAVFLASAPRGVPLALTQFVKHNRVLHERVLLVTVLIEESPHIPDEERAEVIEIIPGITRVILHYGFMQNPTIFDGLTLTCRQGKLPGIDLSDITYYVGRETIIPREDVPGMWVWREGLFAFLQRNAERSAAFFGVPTKQVVEFGTELEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 3.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSCLA_ARATH
Sequence: MEISALLTSAGINISICIVLLSLYSILRKQPANYCVYFGRRLVCGGARRYDPFWYERFVPSPSWLVKAWETSEDELLAAAGLDAVVFLRMVIFSIRIFFIVAVICIAFVLPVNYYGQPMVHKEIHLESSEVFTIENLKEGSKWLWVHCLALYIITSAACLLLYFEYSTIAKMRLGHITGCASKPSQFTVLIRAIPWSPEQSYSDTLSKFFTNYYSSSYVSHQMVYHNGIIQRLLRDAERMCQTLKHVSPEINCKPSLRPCTFCGGPTATSSFHILSNEADSVKGMELGELTMTTTTTEQERSAAFVFFKTRYDALVVSEVLQSSNPMLWVTDLAPEPHDVYWKNLNIPYRQLWIRKIATLVGAVAFMFVFLIPVTFIQGLTQLVQLSHAFPFLRGILSKNFINQVITGYLPSVILILFFYAVPPLMMYFSALEGCISRSIRKKSACIKVLYFTIWNVFFVNILSGSVIRQLNVFSSVRDIPAQLARAVPTQAGFFMTYCFTSGWASLACEIMQPMALIWNLVAKVVTKNEDESYETLRFPYHTEIPRLLLFGLLGFTNSVIAPLILPFLLIYFFLAYLIYKNQILNVYITKYESGGQYWPIFHNTTIFSLILTQIIALGFFGLKLSTVASGFTIPLILLTLLFSEYCRQRFAPIFNKNPAQVLIDMDRADEISGKMEELHKKLHNVYSQIPLHSQKSSSKAECSNPFKKQELPDPEKLKPEEGDAIAKELWGFQGNESGQEHDTKS
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel.
What are the official names of this protein?
CSC1-like protein RXW8.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENSA_RAT
Sequence: MSQKQEEENPAEETGEEKQDTQEKEGILPEKAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGADKNLVTGDHIPTPQDLPQRKSSLVTSKLAGGQVE
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.  Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents (By similarity).
What are the official names of this protein?
Alpha-endosulfine, ARPP-19e.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAS_SHEVD
Sequence: MSQEFNVVVLGASGAVGQTMIEILEERNFPVAKLFPLASSRSAGGTVSFNGKQVEILDVDDFDWSQAQIGFFSAGGDVSEKWAPIAAENGCVVIDNTSQFRYDNDVPLVIPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAFGISRINVATYQSVSGSGKEAITELAGQCSKLLQGLPAESKVYPKQIAFNVLPQIDKFMENGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVPVFYGHSEAIHLETIQPAEAEDVKAVLREAPGIELFESNEEYPTAVTESAGTDPVYVGRVRKDISHSHGINLWVVSDNIRKGAALNSVQIAEVLIRDYY
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: LEXA_SPHAL
Sequence: MLTAKQHELLHFIQQRLDASGISPSFEEMKEALGLKSKSGIHRLISALEERGFLRRLPNRARALEVLKLPDTAKSVVTNNRDNVVQLRKAPSALKPIAANDIIEVPLHGRIAAGVPIEAFEDHEQLAVPAALLGSGEHYALEVSGDSMVEAGIFDGDYALIQKADTAREGDIVVALVDGQDATLKFFRREGKMIRLDPANSAYEPQRYPAERVIVQGRLSGLLRRYH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y2447_LISMF
Sequence: MASKQLKLVIITGMSGAGKTVAMQSLEDLGYFCVDNLPPSLLPKFWELMKESDKMDKIALVMDLRGREFFDSIEPALDELDNTNFITTKILFLEADDKVLVSRYKETRRHHPLEPNGSVLDGINAERELLSDLKGRSQLVINTSNMAPRELRERINNEFQTEDKDIFNVQLMSFGFKYGIPIDADLVFDVRFLPNPHYIDKMRPLTGLDEDVYEYVMKWPETQTFLDKLVDLLMFTLPFYKREGKTQLVIAIGCTGGQHRSVALTEFVGKAIQQKYETTISHRDMKRRKGR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein LMOf2365_2447.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: GATA_LEIXX
Sequence: MTDLTRLSAAALADLLAAGEISSVEATRAHLGRIEAVDADVHAFLHVAGEKALRTAAEIDGRRASGEKLGPFAGVPVAIKDVLATNDMPSTSGSKILEGWLPPYDATVVRKLREADLVPLGKTNMDEFAMGSSTEHSAYGPTRNPWDLERIPGGSGGGSAAAVSAFEAPLALGSDTGGSIRQPAAVTGSVGVKPTYGGVSRYGAIALASSLDQVGPVSRTVLDAGLLHDVIAGHDALDSTSLTDVWPSMADAARAGAREGALRRVRVGVVRELNGEGFQAGVKQRFEESLGLLEGAGAEIVEVSAPSFEYAVAAYYLILPAEASSNLARFDSVRFGLQVDPAEGPVTVERVMAATRDAGFGPEVKRRIILGTYALSAGYYDAYYGSAQKVRTLIQRDFSAAFERVDVLVSPSAPTTAFRFGEKLHDPMAMYLNDITTIPANLAGVPGMGLPIGLAPEDGLPVGLQLMAPAHADARLYTIGAALERLLEEKWGGPLLAQAPDLSATEMLASEEGAV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PTH_HYDCU
Sequence: MSSVKLIVGLGNPGGQYEQTRHNAGFWFVEDVARQYNVQFRPETKFLGEAARIQSNGLDVWLLKPMTFMNRSGQSIQAIAKFYKIAPEEILVVHDELDLDPGVARLKTSGGHGGHNGLRDTIAALGTKDFKRLRLGIGHPGDRNQVVDYVLKAPSKTDRALIDDAIYDATRVLPDLLNDDMARAMNELHTKT
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF17_HUMAN
Sequence: MAAEASKTGPSRSSYQRMGRKSQPWGAAEIQCTRCGRRVSRSSGHHCELQCGHAFCELCLLMTEECTTIICPDCEVATAVNTRQRYYPMAGYIKEDSIMEKLQPKTIKNCSQDFKKTADQLTTGLERSASTDKTLLNSSAVMLDTNTAEEIDEALNTAHHSFEQLSIAGKALEHMQKQTIEERERVIEVVEKQFDQLLAFFDSRKKNLCEEFARTTDDYLSNLIKAKSYIEEKKNNLNAAMNIARALQLSPSLRTYCDLNQIIRTLQLTSDSELAQVSSPQLRNPPRLSVNCSEIICMFNNMGKIEFRDSTKCYPQENEIRQNVQKKYNNKKELSCYDTYPPLEKKKVDMSVLTSEAPPPPLQPETNDVHLEAKNFQPQKDVATASPKTIAVLPQMGSSPDVIIEEIIEDNVESSAELVFVSHVIDPCHFYIRKYSQIKDAKVLEKKVNEFCNRSSHLDPSDILELGARIFVSSIKNGMWCRGTITELIPIEGRNTRKPCSPTRLFVHEVALIQIFMVDFGNSEVLIVTGVVDTHVRPEHSAKQHIALNDLCLVLRKSEPYTEGLLKDIQPLAQPCSLKDIVPQNSNEGWEEEAKVEFLKMVNNKAVSMKVFREEDGVLIVDLQKPPPNKISSDMPVSLRDALVFMELAKFKSQSLRSHFEKNTTLHYHPPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGAPEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLYLTGAVATIILQVDSEENNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRINNLDNSHSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADIISEQKVSEFQEKILEPRTTRGYKPPAIPNMNVFEATVSCVGDDGTIFVVPKLSEFELIKMTNEIQSNLKCLGLLEPYFWKKGEACAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYPDIPQFCIPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIMELPKNPWEKLSIHLYFDGMSLSYFMAYYKYCTSEHTEEMLKEKPRSDHDKKYEEEQWEIRFEELLSAETDTPLLPPYLSSSLPSPGELYAVQVKHVVSPNEVYICLDSIETSNQSNQHSDTDDSGVSGESESESLDEALQRVNKKVEALPPLTDFRTEMPCLAEYDDGLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIPSHLMRYPARAIKVLLAGFKPPLRDLGETRIPYCPKWSMEALWAMIDCLQGKQLYAVSMAPAPEQIVTLYDDEQHPVHMPLVEMGLADKDE
What is the function of this protein?
Seems to be involved in regulation of transcriptional activity of MYC.  In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers.  Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm.  May be involved in spermiogenesis (By similarity).
What are the official names of this protein?
RING finger protein 17, Tudor domain-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly found in the cytoplasm. Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity).
Protein: YGIB_SHIF8
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: TIG_PARUW
Sequence: MSNQETEAGSKTISNDNLNVQITRGTHCQVKFDITVKPEAVVAAYQKALKTINKEINIPGFRKGKAPQQLILEKYGSNVQKECVDIVLQTGFNDALQLTHIHPLKDGHIKRPIVHYCTQEKGAHFVLEFEARPTIPSVQPQELHLHHQAPVQVTDEERKNALDQVLLQFTTYQPIEDRPVQEGDFINVDVTILEETPRLIIDNQRTQVNQSGLPSWIQEKVIGLNAGASAEGMTQPNEKFPDPDFKSVPFRVTVKTIWQGNMPAIDDELAKKVGLQTVDELYQKLNERLEQEAQEDIYKQHIHHLEDQLIEKYPFDLPLSYIESNKQARLDDYLKQLGQESQLPQNYEEIEKMIENSTIRGLQLYFLLRRVAADNKLEVSEEEVSQELSKQIALIPSGKSQIDIYGDKSKLREQLYNLALDRKIKKFLLDQAQWV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ATPA_ACOCL
Sequence: MATLRADEISNIIRERIEQYTREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLTIQEGSSVKATGRIAQIPVSEAYLGRVVNALAKPIDGRGEIAASEFRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPVGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTSIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKSSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELEAFAQFASDLDKATQNQLARGKRLRELLKQSQSEPLAVDEQVVTIYTGTNGYLDTLEIGQVKEFLVKLRTYLKKNKPQFQEIISSTKTFTEEAEALLKEAIQEQLELFLLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CSHL_HUMAN
Sequence: MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEFISSWGMEAYITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEPVRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTNSHNHDALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGSCGF
What is the function of this protein?
May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation.
What are the official names of this protein?
Chorionic somatomammotropin hormone-like 1, Chorionic somatomammotropin-like, Lactogen-like.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTPD_ECO57
Sequence: MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELRLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGVVLMIWLYQALKFRNRALALES
What is the function of this protein?
Probable proton-dependent permease that transports dipeptides.
What are the official names of this protein?
Dipeptide permease D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_NOVAD
Sequence: MSDSDKKPTLGRRPLGLKTAVEAGEVKQTFSHGRTNKVVVEVKRRKLMGRPGEAAPTAAPAAAATPAPTPVAPPPPPPPPPPPPSASRETRQEMQVRLLREAEEARLAALEAANRREQEERLRAIEEERRRAEEKARAEAEAAAAPAAPAAPAAPSAAPAAAQSAPEAAPAPVAEPEVARQPEAAPVAATAPAAPKAEEAKPAAPAVPAPRRFTPVAPAAPIKRPELAAKKPAHPQRDRKTEDRRGGKLTVTRALNEDEGARARSLAALKRAREKERRAHFAGQSQPREKQVRDVVVPDAITVQDLANRMAEKAADLVKALFKMGMMVTINQTIDQDTAELLVTEFGHNIQRVSESDADIDTSADVDPEESLKARPPVVTIMGHVDHGKTSLLDALRGTDVVRGEAGGITQHIGAYQIKTKGGDFITFLDTPGHEAFTEMRIRGANVTDIVILVVAGDDGLMPQTIEAINHTKAAGVPMIVAITKADKPEFQPQKIRERLLEHEIIVEAMSGDVQDVEVSAKTGAGLDELIEKILLQAELLELKANPDRSAEATVIEAKLDKGKGPLATVLVNRGTLKVGDILVVGTQSGRVRAMLDDKGRQVKAAGPSLPVEVLGIGGVPMAGDTLTVVESEARAREVAAYRQERATAKRTAQAPASLENMFSALAAKNAVIEYPLVIRADVQGSAEAIVNALNKISTDEIKVRILASGVGAITESDVNLAQASGAPIVGFNVRPNAKARELIERNKVRMKYFDVIYQLTDDIRSEMAGELGPEAIETVVGRAEVKEVFPAGKRDKAAGLLVVEGVIRKGLHARLTRNDVIVSRTTIASLRRFKDDVPEVRAGLECGVLLQDTNDIKAGDQLEVFEVEMRERTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_METPP
Sequence: MRFDVLTLFPELFAPFQAVGVTRRAFESGAIDLKLWQPRDFADNAYRRVDDRPYGGGPGMVMLVEPLERALAAVRDDQAAAGAARTPVLLFSPAGAPLTQRRVEALASEAGAVLVCGRYEGIDQRFIDRHVDEELSLGDFVLSGGELPALALVDAVARLQPGVLNDQTSHQQDSFSDGLLDCPHYSRPEHLGDAAADGVPATLMSGHHAEIARWRRERQLELTARRRPDLIAAARAQGRLTKADERYLQSLPGLGL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPE_YERPS
Sequence: MKISSFISTSLPLPTSVSGSSSVGEMSGRSVSQQTSDQYANNLAGRTESPQGSSLASRIIERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQLNSLDAEMLQKNHDQFATGSGPLRGSITQCQGLMQFCGGELQAEASAILNTPVCGIPFSQWGTIGGAASAYVASGVDLTQAANEIKGLAQQMQKLLSLM
What is the function of this protein?
Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis.
What are the official names of this protein?
Outer membrane virulence protein YopE.
What is the protein family that this protein belongs to?
Belongs to the YopE family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y1494_XYLFA
Sequence: MVEQLLLPLWNSLATVDDETLPLMSTALLIARDEYPDLDANLYDTLVQSYVEYLRSEVEEISLWPLKMAAVNRYLFQKLGYSGNHDEYYDPRNSYLNQVFERRLGNPISLAVIQIEVARRLGIPLDGVSFPGHFLVRLPVDDGILVMDPFNGGRPLDAEELRERVRPHLGGEVPDDRALAQILNPAPHRTILVRILRNLHSVYANTNRWDRAARCADRILKLVPNQPEALRDRGLAYLQLGHRSGARNDLTRYLQLYPSTHNVDMVRGHLVDLSNERIQTH
What are the official names of this protein?
UPF0162 protein XF_1494.
What is the protein family that this protein belongs to?
Belongs to the UPF0162 family.
Protein: ODO2_STAS1
Sequence: MPEVKVPELAESITEGTIAEWLKQVGDSVDKGEAIVELETDKVNVEVVSEEAGVLQELLANEGDTVEVGQAIAVVGEGSGNNTSEAPAKQEAPKQETETSTDDKSAQPAEATSNDTDDKSQDNNQRVNATPSARKYAREKGIDLSEIAAASNDVVRKEHVDQSQTQTSTQQQAQPAAKEETKKLTQQNPSKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEIDMTNVMDLRKRKKEQFIKDHDGTKLGFMSFFTKAAVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTEDGLLVPFVRDCDKKNFAEIEDEIGNLAKKARDKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGSQAAILGMHSIITRPIAIDADTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
What is the function of this protein?
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: OTSA_ECO57
Sequence: MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPTPEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKAFRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDEVAVALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQIVPRSAESQQRDKVATFPKLV
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: MVHA_METTM
Sequence: MVKLTMEPVTRIEGHAKITVHLDDAGNVEDTRLHVMEFRGFEKFLQGRPIEEAPRIVPRICGICDVQHHLAAAKAVDACFGFEPDDVLPAAYKMREIMNWGSYMHSHGLHFYFLAAPDFIAGKDRKTRNVFQIIKDAPDVALQAIELRKNALEIVRATGGRPIHPTSSTPGGISTELDDETQKDLLQKAQRNVELAEATLELAVPIFEENIDLVNSLGNIETYHTGLVKNGVWDVYDGIVRIKDKEGNLFREFKPADYADTIAEHVKPYSWLKFPYIKDLGYPDGVYRVSPLSRLNVADKMPDAAPKAQDYFKEFQDKFGYAQQTLLYHWARLIEVLACAECAADALEGDLSGEKFPDSLERQAGDGVGIVEAPRGTLTHHYTCDENGLITKANIVVATIQNNPAMEMGIQKVAQDYIKPGVEVDDKIFNLMEMVIRAYDPCLSCATHTIDSQMRLATLEVYDSEGDLVKRI
What is the function of this protein?
Part of a complex that provides reducing equivalents for heterodisulfide reductase.
What are the official names of this protein?
F420-non-reducing hydrogenase subunit A, Methyl viologen-reducing hydrogenase subunit alpha, MVH subunit A.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: METAS_KLEP3
Sequence: MPIRVQDELPAVSFLRNENVFVMTTTRATTQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDEICDQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTRAEKISGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAGLIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDANTLASEYFRDVEAGLNPEVPYNYFPQNDPQNKPRATWRSHGNLLFANWLNYYVYQITPYDLRHMNPTLE
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.