PharMolix/UniProtQA huggingface dataset:
Protein: PPNP_ECO45
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: HISZ_LARHH
Sequence: MHNWLLPEHIADILPATARQLESAKAAMLERFRRYGYELVSPPLIEYTDSLLTNADPALDMQTFKLDDQLSGRQLGLRADMTPQVARIDAHLLAHRQGVTRLCYAGSVVHTRASGLMRSREPLQVGAELYGCYDLAADIEIIELMLSTLAGVGIDAVTLDLGHLGVYRALVREAQLDGETEQALFAALQAKDRASVEALTADVREPFCSAFRHLVDLYGPEAIGKARARLPGLPGIRAALDDLERLAQIFASRARISFDLTELRGTHYHTGLMFAAYAEGWAEELARGGRYDNVGRRFGRARPATGFSLDLRDMIRVLPQTHPSKGIRVRAADLSRLADEVARLRAAGEVVVVDYLGETAADLHCDRELVCREEGQSLEAAPAHP
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOM20_XENTR
Sequence: MVVVGKTSAIAAGVCGALFLGYCIYFDRKRRSDPNFKNRLREKRRKQKIAKERAGQSRLPDLKDAEAVQKFFLEEIQLGEELLAQGDFEKGVDHLTNAIAICGQPQQLLQVLQQTLPPPVFQMLLTKLPTINQRIGNAQNLAEDDVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial 20 kDa outer membrane protein, Outer mitochondrial membrane receptor Tom20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RNPA_MYCMS
Sequence: MKNKRVIKKNFEFQEIINYKKTIKNFCFIIYYKDNDQSYLKYGISVGKKIGNAVVRNKVKRQIRMILRQNINEIGTISKDVIILVRKSVLKLKYATLSKSLIKLIKEIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: OCTB2_CHISP
Sequence: MDPINGSHSGANATISDITNGAYNATDAGEWTSSVMFKLRTCVLLLIVIMAVLGNMLVIVSVMRHRKLRVITNYFVVSLAFADILVAMVVMPFNFSVQFNQGWVFGETICDLWNSSDVYFTSTSILHLCCISVDRYYAIVKPLKYPIKMTKKMAFVMLAATWLSPITISYVPIFMGWYTTTDFLESRRDDQCEFKVNKPYAVISSSISFWIPCTIMIFTYLAIFKEANRQEKALHARAGNAMLMHRHSREVSDKNGALHINATTPTKDRNLLKMKREHKAARTLGIIMGAFILCWLPFFLYYVSTSLCDSCNCPEVVTVIMFWTGYFNSALNPIIYAYFNRDFRNAFKNTLACAFCSFCKRSASDLDAMERLDRRGSAQLRVPIPSRRASDLASL
What is the function of this protein?
Autoreceptor for octopamine, which is a neurotransmitter, neurohormone, and neuromodulator in invertebrates.  Also acts as a receptor for tyramine, but with much less potency.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Octopamine receptor beta-2R, CsOA2B2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAK_BORRA
Sequence: MGKIIGIDLGTTNSCVAIMEHGKPVVIQNSEGGRTTPSIVAYTNKGERLVGQVAKNQMVTNPENTIYSIKRFMGRRFEEVASEIKMVPYKVEKGQNGDARVNISNIKKQMSPPEISAATLTKMKETAEAYLGEKVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIVNEPTAAALAYGIEKKHEEIVAVYDLGGGTFDISILELGDGVFEVKSTNGDTHLGGDNFDDEIIKYLITEFKKDSAIDLSNDKMALQRLKEAAEKAKIELSGAQEASINLPFITADANGPKHLQYTLTRAKFEQMVDHLVQKTKEPCLKAIKDAGLKASDINEVILVGGSTRIPAIQKIVKEIFGQEPNKGVNPDEAVAIGAAIQGGILTGEAKDMVLLDVTPLSLGIETLGGVMTKLIERNTTIPTKKSQVFSTAADNQTSVDIKVLQGEREMASQNRVLGNFILDGIPAAPRGVPQIEVSFDIDANGIVHVSAKDMGTGKEQKIRIESSSGLSEEEIERMVKDAESHAEEDKKLKEGIEAKNIANSLIYQTEKSLKEYGEKITNQDKEAIENKIKELKDTLEGSDISLLKSKTEELQQASYKIAEMMYKDAQASSPAQNNAQNNAGSESKEADYEVVDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AAS_ESCF3
Sequence: MLFGFFRKLCQVLYRVQVTGDPAALKGERVLITPNHVSFIDGILLALFLPVRPVFAVYTSISQQWYMRWLQSLIDFVPLDPTKPMAIKHLVRLVEQGRPVVIFPEGRITVTGSLMKIYDGAGFVAAKSGATVVPVRIEGAELTHFSRLKGLVKRRLFPKIHLHILPPTHVPMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLGAMHRYGGGKNCVEDVNFTPDSYRKLLTKTLFVGRILEKYSAEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWIYLEDLKADVTLTDKVWIFAHLLMPHLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIEDGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENIQGELERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDSELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEPEKHNE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECTC_WOLSU
Sequence: MIVKTKEEVVGTPREIFAPNGHWISRRYLLAGEGMGFSFHETIILAGTKTHIHYQNHLEAVFCVQGRGEVELIPSGERFLIEEGVMYALDKHDEHYLSASEEMRLICVFNPPLQGNEVHDEKGVYPLKKGQ
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: FABZ_ROSCS
Sequence: MLNIQEIMAIIPHRYPFLLIDRILELEPGQRAVGEKLVTINEPFFQGHFPAHPIMPGVLIVEALAQTGAVAALSLPENRGKIAFFAGIDGVRFRKPVYPGDTLRLEVRFDKMRRGIGKGTGVATVDGQVVCEGELMFALHVER
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_VIBCH
Sequence: MDKTLKFTESHEWVRDNGDGTVTIGISEHAQEMLGDVVFVELPEIDAEIDAGDSFSLVESVKAASDIYAPVTGVVIEVNEDLQNSPELINEEPYDGGWIVKVKMSDPDELKDLKDAEEYLASIEED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: LEU3_SHIFL
Sequence: MSKNYHIAVLPGDGIGPEVMTQALKVLNAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDIQCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAASAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_CHLRE
Sequence: MATKLFPKFSQGLAQDPTTRRIWYGLAMAHDFESHDGMTEENLYQKIFASHFGQLSIIFLWTSGNLFHVAWQGNFEQWVTDPVHIRPIAHAIWDPHFGQPAVEAFTRGGASGPVNISTSGVYQWWYTIGMRTNQDLYVGSVFLALVSAIFLFAGWLHLQPNFQPSLSWFKDAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGQHVGWDNFLSVLPHPQGLTPFFTGNWAAYAQSPDTASHVFGTAQGSGQAILTFLGGFHPQTQSLWLTDMAHHHLAIAVIFIVAGHMYRTNFGIGHRMQAILEAHTPPSGSLGAGHKGLFDTVNNSLHFQLGLALASVGTITSLVAQHMYSLPPYAFQAIDFTTQAALYTHHQYIAGFIMCGAFAHGAIFFIRDYDPEQNKGNVLARMLDHKEALISHLSWVSLFLGFHTLGLYVHNDVMQAFGTPEKQILIEPVFAQWIQAAHGKALYGFDFLLSSKTSAAFANGQSLWLPGWLDAINNNQNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAYDAFYLAVFWMLNTIGWVTFYWHWKHLTLWQGNVAQFDESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWTFLFGHLIYATGFMFLISWRGYWQELIETLVWAHEKTPLANLVYWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGRFG
What is the function of this protein?
Both potential cofactor branches in PSI seem to be active; however, electron transfer seems to proceed preferentially down the path including the phylloquinone bound by PsaA.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: MGRB_SALCH
Sequence: MKKFRWVVLGIVVVVCLLLWAQVFNIMCDQDVQFFSGICAINKFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DTPB_EDWTE
Sequence: MNNTAPGLLHQPKPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTKRTMVLGAIVLALGYFMTGMSLLKPEMIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLLSLSLAPIIAERFGYAVTYNLCGLGLIIALLVYFACRGMVRSIGSAPDHQPLNYGKLLLVLAGAVVMIFLCAWLMHNVGVANIVLIAVSAVVLYFFFREAFKQDKTGRNRMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVRHELLGFAINPVSFQALNPFWVVVASPILASIYTRLGSRGRDMTMPTKFTLGMLLCSLGFLTAAAAGMWFADAQGLTSPWFVVLVYLFQSLGELMISALGLAMVAALVPQYLMGFILGMWFLTQAAAFLLGGYVATFTAVPAGIHDPLQTLPIYTGVFGKIGIATLIVTLVMAAMVPWLNRMMNTPADGQKA
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NNRE_XENTR
Sequence: MYGLRTLFSLGLLVGGARLGARVAQVGALGGTCPLGQGLVADGNSQCKQFRTGAAMERGLRYLSQEEAQAVDEELFNEYRFSVDQLMELAGLSCAVAITKAYPVSSFTSNLPTVLVVCGPGNNGGDGLVCARHLKLFKGYEPAIHYPKRPNKTLFENLTTQCQKMDIPFVSEFPSEPEVIDGAYNLVVDAVFGFSFKGAVREPFGNILSTLKRVTVPIASVDIPSGWDVEKGNPEGIQPDMLISLTAPKQSAVHFTGRYHFLGGRFVPKALEKKYSLNLPPYPGTECVQKLP
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, Apolipoprotein A-I binding protein, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
What are the subcellular locations of this protein?
Mitochondrion. Secreted.
Protein: RL19_STRS7
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFEGVVISRKGQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: AZOR1_JANSC
Sequence: MTHILRIDASARRDGSVSRDLTTQIVDLLGGEVTIRDLTTAIPQLDEAWIGANFTPADQRTAQQQETLSLSDTLVAEVQAADTLVIGLPIYNFGVPAALKAWVDQIARAGVTFQYTETGPKGLLEGKRAIVAVASGGTEAGSDIDFATGYMRHVLGFIGITDVTFVTADRLMVDPDAAHKTAQTQIEALAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CRN4_CAEEL
Sequence: MAYQHCPFDTLLILDFETTSDAANQDYPCEVIQFAIVAYDVPNDKIREDISFNKYVKPVLNRTLTKNCVDFTGIPQRSIDTADTFDVVYEQFQQWLITLGLEEGKFAFVCDSRQDLWRIAQYQMKLSNIQMPAFFRQYINLYKIFTNEMDRMGPKELSATTNIGKMNEYYDLPTIGRAHDAMDDCLNIATILQRMINMGAKVTVNELLTCCASWRRQPLVYNKEWRSSFMDAGKIFERVLPLVVTTIRAGDFRLEMYGVCRYCRKGMDVCGTSHQQTPHDLYKNEEDPIHFAKIAGYY
What is the function of this protein?
Involved in the degradation of chromosomal DNA.  Contributes to cell killing.
What are the official names of this protein?
Cell death-related nuclease 4.
Protein: HEM3_BURVG
Sequence: MNSETFSAGPKSAPAPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELENALADGRADLAVHSLKDVPMALPDGFALAAIMAREDARDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARYPHLNVLPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEARIRALIDVEDSLPAAGQGALGIEIAAHRSDVAQWLAPLHDPHTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGRRVLSAQACGAVMTAADALALGRAVSDELDAQGARDIVNALLAGSQVGKGDA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PUR7_CHLPD
Sequence: MTKTTLLHEGKAKKVFLTDQSDLVIQEFKDDATAFNNKKKGTIADKGVVNNAISCRLFTLLEEHGIRTHLVEKLSDRDMLCKRLDIIKVEVVVRNIAAGSLVKRYGFKEGFVLQEPLVEFYLKDDDLDDPLMNDFHAVALGVATSEELAILRSRAEAINLVLRQFFADRKLKLVDFKLEFGRHKNEILLGDEISPDTCRFWDLDTNEKMDKDRFRFDMGGVENAYSEVQKRVLELD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: FPG_ACICJ
Sequence: MPELPEVETVMRGLAAKLEGRRLARVVLARPDLRWPIPEGFVQFLSGARVEGFRRRGKYMFMRLDRALSVLIHLGMSGRMTIDSAPLPHQHLTLETDDGAVIGFVDPRRFGALDLVATAAEDSHRLIAGLGPEPLDDAFSPATLASALEGKKTPIKAALLDQSVVAGLGNIYVSEALFRAGILPHRLAGTIGRGRAGRLVPAIKATLTDAIAAGGSSLRDYVQPSGELGYFQHAWKVYDRAGQPCERCPGPAACAGISRTVQSGRATYFCARTQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PORC_ARATH
Sequence: MALQAAYSLLPSTISIQKEGKFNASLKETTFTGSSFSNHLRAEKISTLLTIKEQRRQKPRFSTGIRAQTVTATPPANEASPEQKKTERKGTAVITGASSGLGLATAKALADTGKWHVIMACRNFLKAEKAARSVGMSKEDYTVMHLDLASLESVKQFVENFRRTEQPLDVLVCNAAVYQPTAKEPSFTAEGFEISVGTNHLGHFLLSRLLLDDLKKSDYPSKRMIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLNGQNSSMIDGGEFDGAKAYKDSKVCNMLTMQELHRRYHEETGVTFASLYPGCIATTGLFREHIPLFRLLFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLGKSGVYWSWNNNSSSFENQLSKEASDAEKAKKLWEVSEKLVGLA
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase C, chloroplastic, PCR C, NADPH-protochlorophyllide oxidoreductase C, POR C.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane. Note=Prolamellar body of etiolated seedling.
Protein: ZD20B_DANRE
Sequence: MAPTHVLRCCQRGLAWIPVIFIALVVCWSYYAYVVELCLLVYLVVFHLSFVMFVWSYWKTIFTKPANPSKEFCLPKSEKEQYEKEQRPETQQEILKKVATSLPLYTRTGAGAIRYCDRCQVIKPDRCHHCSACDMCVLKMDHHCPWVNNCVGFSNYKFFILFLTYSLVYCLFIAASVLQYFIKFWTSDLPESHAKFHVLFLFFVAAMFCISILSLFTYHLWLVGKNRSTIEAFRAPVFRNGPDKNGFSLGFSKNIAQVFGDEKKYWLLPVFTSQGDGLSFPTRLVTIDPEQPTECLQPGGAISSLIIVEYCFCKQAKKKKTDE
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.  Catalyzes palmitoylation of Cys residues on protein substrates and has a preference for acyl-CoA with C16 fatty acid chains but may also utilize acyl-CoA with C14 and C18 fatty acid chains.
What are the official names of this protein?
Palmitoyltransferase ZDHHC20-B, Acyltransferase ZDHHC20-B, Zinc finger DHHC domain-containing protein 20-B.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein.
Protein: BPT_XANAC
Sequence: MAIHADTHDDLRLFQTGEHACGYWSGRQARDLVLDPHDPRLGAIYPQALAWGFRRSGDLVYRPHCERCRACVPVRIAVDAFHPDRSQRRCLARNRDLVVRVVAAERTDEQLALYRQYLKHRHPGGGMDQHGATEFDQFLIGGWSHGRFLEIREPAIAHLPGRLLAVAVTDVTEHALSAVYTFYAPEAAARSLGTFAILQQIQWAQRERRAHLYLGYWIDGHAKMNYKRRFSALEAYDGRHWRGLPAHASVD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_SALG2
Sequence: MSLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGMEIAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYDPAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSAMAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: JAGN_DROME
Sequence: MATRGGPMVAGTDGNDFEFRQRVAGTYQISLLNKSRLKYCIFFHALLFFVMLAKLTSDILDHLDIFVLEIEELEVPPPLWWEYVWAASLLTSFLGLSAARGNKVREMQKYMVAILLFAILPLFYCFAYYFSDVWEFATLDKSVELDETDIFVWRGYPYGVFWYAFCFVGFQVHGFTLYFAYNLVKAWKARTATRKFQ
What is the function of this protein?
Required for endoplasmic reticulum organization and proper vesicular traffic during vitellogenesis.  Required for oocyte and bristle growth.
What are the official names of this protein?
Protein jagunal.
What is the protein family that this protein belongs to?
Belongs to the jagunal family.
Protein: REBF_LENAE
Sequence: MTIEFDRPGAHVTAADHRALMSLFPTGVAVITAIDEAGTPHGMTCTSLTSVTLDPPTLLVCLNRASGTLHAVRGGRFGVNLLHARGRRAAEVFSTAVQDRFGEVRWEHSDVTGMPWLAEDAHAFAGCVVRKSTVVGDHEIVLGEVHEVVREHDLPLLYGMREFAVWTPEG
What is the function of this protein?
Catalyzes the NADH-dependent reduction of FAD to provide FADH2 for the halogenase RebH.
What are the official names of this protein?
Flavin reductase (NADPH), Flavin dependent oxidoreductase, Flavin:NAD(P)H reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: HEM1_BURM7
Sequence: MDMQLLTIGINHHTAPVALRERVAFPLEQIKPALSTFKSVFLGHPAPNAPEAAILSTCNRTELYCATNDRAARDAAIRWMSDYHRIPADELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKNAVRTASEAGSLGTYLNQLFQRTFAVAKEVRGTTEIGAQSVSMAAAAVRLAQRIFEQVAQQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGAKLAERFGGRAMPLADLPARMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDARSIVPVIRHMHTQADALRRAEVERARKMLARGDDPDAVLDALSQALTNKLIHGPTSALNRANGADRDSLIDLMRGFYQHAPRSSDTSDR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.