PharMolix/UniProtQA huggingface dataset:
Protein: BETV6_BETPN
Sequence: MAHKSKILIIGGTGYIGKFIVEASAKSGHPTFALVRESTVSDPVKGKLVEKFKGLGVTLLHGDLYDHESLVKAFKQVDVVISTVGHLQLADQVKIIAAIKEAGNIKRFFPSEFGNDVDRVHAVEPAKTAFATKAEIRRKTEAEGIPYTYVSSNFFAGYFLPTLAQPGLTSPPREKVVIFGDGNARAVFNKEDDIGTYTIRAVDDPRTLNKIVYIKPAKNIYSFNEIVALWEKKIGKTLEKIYVPEEKLLKDIQESPIPINVILAINHSVFVKGDHTNFEIEASFGVEASELYPDVKYTTVEEYLQQFV
What is the function of this protein?
Oxidoreductase involved in lignan biosynthesis (PubMed:11606193).  Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers (PubMed:11606193).  Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC) (PubMed:11606193).
What are the official names of this protein?
Phenylcoumaran benzylic ether reductase Betv6, Minor pollen allergen Bet v 6.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: LIVG_SALTY
Sequence: MSQPLLAVNGLMMRFGGLLAVNNVSLELREREIVSLIGPNGAGKTTVFNCLTGFYKPTGGTITLRERHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLLVAQHQQLKTGLFSGLLKTPAFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNPDVIRAYLGEA
What is the function of this protein?
Component of the high-affinity branched-chain amino acid transport system.
What are the official names of this protein?
High-affinity branched-chain amino acid transport ATP-binding protein LivG, LIV-I protein G.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: GCS2_ECOBW
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: RPOB_PHAAO
Sequence: MLQNGNEGMSTIPGFSQIQFEGFCRFINQGLTEEFHKFQKIEDRDQEIEFQLFVETYQLVEPLITERDAVYESLTYSSELYVPAVLIWKTGRNMQEQTVFIGNIPIMNSFGTSIVNGIYRIVINQIVQSPGIYYRSELEHNGVSVYTSTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGSNIREILDNVCYPEIFLSFPNDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGKIGRQNLNRRLNLDIPQNNTFLLPRDLLAAVDHLIGMKLGMGTLDDMSHLKNKRIRSVADLLQDQFGLALVRLENTVRGTICGAIRHKLIPTPQNLVTSTSLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKWSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLMGSLAIHVKVGYWGSIESPFYGLSERSKEAQMVYLSPNRDEYYMVAAGNSLALNRDIQEQQVVPARYRQEFLTIAWEEIHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLEGQTALDSGVSVIAECKGKIIYTDTQKIFLSSNGDTLSIPLVMYQRSNKNTCMNQKTQVQRGKYIKKGQILAGGAATAGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYKDIYTSFHIRKYEIQTHVTSQGPERITKEIPHLEARLLRNLDRNGIVMLGSWIETGDILVGKLTPQTASESSYAPEDRLLRAILGIQVSTSKETSLRLPIGGRGRVIDVRWIHRRGVSNSNPERIRVYISQKREIKVGDKVAGRHGNKGIISKILSRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLKKHYRIGPFDERYEQEASRKLVFSELYEASKKTKNPWVFEPEYPGKSRIFDGRTGDLFEQPVLIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGAMIIGATVPNPESAPESFRLLVRELRSLSLELNHFLVSEKNFQMDRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 1433B_HORVU
Sequence: MAQPAELSREENVYMAKLAEQAERYEEMVEFMEKVAKTVDSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDRVTLIKDYRGKIEVELTKICDGILKLLDSHLVPSSTAPESKVFYLKMKGDYYRYLAEFKSGTERKDAAENTMVAYKAAQEIALAELPPTHPIRLGLALNFSVFYYEILNSPDRACDLAKQAFDEAISELDSLSEESYKDSTLIMQLLRDNLTLWTSDISEDAAEEMKDAPKGESGDGQ
What are the official names of this protein?
14-3-3-like protein B, 14-3-3B.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: LECG_TRIST
Sequence: MGRFIFVSFGLLVVFLSLSGAKGSCCTNDSLPMNGMCYKIFDEPKTWEDAEMFCRKYKPGCHLASFHRLAESLDIAEYISDYHKRQAEVWIGLLDRKKDFSWEWTDRSCTDYLNWDKNQPDHYKDKEFCVELVSLTGYHRWNDQVCESKNSFLCQCKF
What is the function of this protein?
Galactose-binding protein which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids.  May be a calcium-dependent lectin.
What are the official names of this protein?
C-type lectin TsL, Galactose-binding lectin, CTL.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: T231C_BACTB
Sequence: MNLSIQDELQLFSEELYRHLTPSLLEELAKELGFVKRKRKFSGNELATICIWVSQRTASDSLVRLCSQLHAATGPLMSPEGLNKRFDKKAVEFLKYIFSALWKSKLCKTSAISSAALTYFQRIRILDATIFQVPKHLAHVYPGSGGCAQTAGIKIQLEYDLHSGQFLNFQVGPGKNNDKTFGTDCLDTLRPGDLCIRDLGYFSLEDLDQMDQRGVCYISRLKLNHTVYTKNPFPEYFRNGTIKKQSQYIQVDLENIMHTLKPGQTYEIKESYIGKNQRLFTRVIIYRLTEEQILERRKKQSYTESKKGITFSEKSKRLTGINIYVTNTPWEVVPMEQIHDFYSLRWQIEIIFKTWKSLFQIHHWQTIKQERLECHVYGKLIAIFICSSTMFKMRQLLLQKHKRELSEYKAIGMIQDHLSLLYQAIQRNTRIITKVLIRLFTLLKKNGRKSHRYEKKTIFDIMGVVYEYNGLRKQKKAA
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Transposase for insertion sequence element IS231C.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: AROK_THEPX
Sequence: MKNIVLTGFMATGKTTVGKKVATTMSFGFIDTDKMIEKMANMTVSDIFEKYGENYFRKLEKAAVKKAARLKNFVIATGGGVVLNPSNIVQLRKNGVVICFVARPEIILRNIGKNKDRPLLMVDNPEEKIRQLLKEREPFYRFADYTIDVSDMTIDEVAEEVIKAYIRLKKG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRSF5_RAT
Sequence: MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN
What is the function of this protein?
May be required for progression through G1 and entry into S phase of cell growth.  May play a regulatory role in pre-mRNA splicing.  Autoregulates its own expression.  Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity).  Could play an important role in development and differentiation in the spleen and thymus.
What are the official names of this protein?
Serine/arginine-rich splicing factor 5, Delayed-early protein HRS, Insulin-induced growth response protein CL-4, Pre-mRNA-splicing factor SRP40, Splicing factor, arginine/serine-rich 5.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: P1196_TITST
Sequence: KIKETNA
What are the official names of this protein?
Peptide 1196.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_CLOBJ
Sequence: MAKVQYFGTGRRKKSVARVRLVAGDGKVIINNRDIENYFPIETLRVIVNQPLVLTETKDKYDVLVNVHGGGFTGQAGAVRHGISRALVKADENMKSSLKKAGFLTRDPRMKERKKYGLKKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: BPT_CAMJ8
Sequence: MLEIGFCTLEDQCPYLKDKRSRIEYKYIENCSKEINNELIKRGWRRFGRYFSRPICKDCDECLSLRILVNEYNFSRSERRVINKNINTKVILRTPNLSNEHLFLYDKYHRFMEEKKNWKRYDLSFKQYYNLYVDGFMNFGYELAFYIEDKLVCVDLIDILEDGISSIYCFYDPDFSYFSLGKFSLLNEIQIAKKMNLDYIYLGYFVKKCQSLSYKADYTPNEILKGTKELFENEVLWEK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABP_ACASI
Sequence: QINGSYKLEKSDNFDAFLKELGLNFVTRNLAKSATPTVEVSVNGDSYTIKTASTLKNTEISFKL
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PS1C1_HUMAN
Sequence: MTCTDQKSHSQRALGTQTPALQGPQLLNTDPSSEETRPPHVNPDRLCHMEPANHFWHAGDLQAMISKEFHLAATQDDCRKGRTQEDILVPSSHPELFASVLPMAPEEAARLQQPQPLPPPSGIHLSASRTLAPTLLYSSPPSHSPFGLSSLI
What are the official names of this protein?
Psoriasis susceptibility 1 candidate gene 1 protein, Protein SEEK1.
Protein: ADRC3_ARATH
Sequence: MSTHSSISQPPLPLAGRVAIVTGSSRGIGRAIAIHLAELGARIVINYTSKAADAERVASEINDFPVREEITGKGPRAIVVQANVSEPSQVKSMFDAAESAFEAPVHILVNSAGILDPKYPTIADTSVEDFDHTFSVNTKGAFLCSKEAANRLKQGGGGRIILLTSSQTRSLKPGFGAYAASKAAVETMVKILAKELKGTGITANCVAPGPIATEMFFDGKTPELVEKIAAESPFGRVGEAKDVVPLVGFLAGDGGEWVNGQIIPVNGGYV
What is the function of this protein?
Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons.
What are the official names of this protein?
NADPH-dependent aldehyde reductase-like protein, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL30_ALKCK
Sequence: MAKKLEITLTRSLIGRPSDQRVTVNTLGLRKLHQTVVQEDNAAIRGMVNKVKHLITVNEIDA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: YIDA_SHIFL
Sequence: MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTGRPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSREVGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEPAILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAIGDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN
What is the function of this protein?
Catalyzes the dephosphorylation of different sugar phosphates.
What are the official names of this protein?
Sugar phosphatase YidA.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: UVRB_STRU0
Sequence: MIDRRDENTFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSAVSLRPGQEISRDQLLNQLVDIQFERNDFDFQRGRFRVRGDVVEVFPASRDEHAFRIEFFGDEIDRIREIESLTGKILGEAEHLVLFPATHFVTNDEHMEASIAKIQAELASQLKVFESEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKKMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYELEQTDTIVEQIIRPTGLLDPIVEVRPTMGQMDDLLGEINLRTERGERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSQGRVIMYADKMTESMQKAIDETARRRQIQMAYNEEHGIVPQTIKKEIRDLISITKGTNTEVEEESLDYSVMTKSERQEAIKKLQKQMHEAAELLDFELAAQIRDMVLELKSMD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNG1_MOUSE
Sequence: MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNACSYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDPSQDSSMPYAPYVEPSAGSDPAGMGGTYQHPANAFDAEPQGYQSQGY
What is the function of this protein?
May play a role in regulated exocytosis.  Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity).  Involved in the regulation of short-term and long-term synaptic plasticity (PubMed:10595519).
What are the official names of this protein?
Synaptogyrin-1.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome.
Protein: MINE_SHEPC
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVQISDDQVSVQLDQNDDNLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: YIDC_LEPBL
Sequence: MEDRQSRLFLALILSMGIWMGVNYFFFPPTPKKTSETKEVKVDKPSDDKQDQIQKEKKESRTTIPSKGTKIIPSESKKTLVVTESYIVEFSSLGGRISKFYVKDFTGPNGELVQVARKDPETLIVDGKTYYGVELSREKGFDFNFTDSLNELPHSEWNRIPFSLAENKADHSVVFSAFSPDKTYQLKKTFRFFDRENYFKVTVSVINLTKEKLSFASQKNVQYLRTFGSLGPFPKDRPLNDRDTANFFRFYHLDGSFNDTLDGSSSVGFWSSIVNFFTGNSGVDESFSLKTSTGGVDFAGTGSRYFIAVADPLDHKPQGIILDNRPKNESGAVLVYNNITLGPGEVYNLDFASYVGIRESIGMVFHDPELDPSQTKNSPFAGLSSDLNKSFNQGITTPFRNGIIWVLKQIYRFTIPNYGWSIIIFAILFKLVFYPLNQKQAESMKKMQELSPQLKTINEKFANDPKMRQQKTMELYKKNNVNPVGGCLPMVIQIPIFIALYTAFSDTIDLWNSPFLWVKDLSEPDVIWTSPAIPYFTQTGIGLNLLALLMVGTQIFQTRMTSVSMDPNQKMLMYVMPVMMLYIFWNMPSGVTLYWTFQNVLSIGQQWVTNHLKKTEAKKKAV
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPMA_ECOHS
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: TRMB_CUTAK
Sequence: MRPDPAPLDPTDASPAQARRHQPGLGVEVSAGAHRSGDRVRRGVVSFVRRSPRMNVSQQRAMNTLASTYLIDVPRDATSTSVAPGSRLDLPAIFGRTAPLTVEIGVGSGDVLAALAAAHPERDFIGFEVYLPSIATTLNKLENAGASNARVIMADATAGLDHLFGPADLDELWTFFADPWHKKRHHKRRIVNPDTARLVTSRLRPGGLWRLATDWDDYAHWMLEVLSAEPLLKPVDAGPDGFSPRWPERPVTRYENKGLTAGRTIHDLTWRRVDES
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: YTR1_BUCSC
Sequence: MIRKTIILLLFIIVSITWGTTFIAIRIASDTIPPLCITGMRFLLASFFLIFLCFYTKTPLLFPSNKKIFQLIICIFYFSLPFLLILYGGRYVNSTIASVIFAIMPIIVLFLSFIFFNKKLYFFQFIGLVLAIIFLSIILFKEIELGDEKTIKGVIALLLAMTSHAIIYLYSKEKYSNISILTFNALPSLLSGLFFLVISNILEHPKFDNFSNISILATFYLSYFSGVFGILSYFYLQKKVSAFQASTIFFIFPIINLMLEEFVWGNSIGIDQLQLIVFLMSSILITIFPFDLKNFMRFIKNFKK
What are the official names of this protein?
Uncharacterized transporter in trpA 3'region.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CKLF6_PONAB
Sequence: MENGAVYSPTTEEDPGPARGPRSGLAAYCFLGRLPLLRRVLKGLQLSLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILIVYCTPFYERVDTTKVKSSDFYITLGTGCVFLLASIIFVSTHDRTSAEIAAIVFGFIASFMFLLDFVTMLYEKRQESQLRKSENTTRAEALTEPLNA
What is the function of this protein?
Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity.  Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination.  May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 6, Chemokine-like factor superfamily member 6.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane. Note=Co-localizes with PD-L1/CD274 in the plasma membrane and in recycling endosomes.
Protein: PSBJ_LIRTU
Sequence: MADTTGRIPLWLIGTVTGIPVIGSMGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: REP_PCV1
Sequence: MPSKKSGPQPHKRWVFTLNNPSEEEKNKIRELPISLFDYFVCGEEGLEEGRTPHLQGFANFAKKQTFNKVKWYFGARCHIEKAKGTDQQNKEYCSKEGHILIECGAPRNQGKRSDLSTAVSTLLETGSLVTVAEQFPVTYVRNFRGLAELLKVSGKMQQRDWKTAVHVIVGPPGCGKSQWARNFAEPSDTYWKPSRNKWWDGYHGEEVVVLDDFYGWLPWDDLLRLCDRYPLTVETKGGTVPFLARSILITSNQAPQEWYSSTAVPAVEALYRRITTLQFWKTAGEQSTEVPEGRFEAVDPPCALFPYKINY
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep and/or Rep' binds a specific hairpin at the genome origin of replication.  Introduces an endonucleolytic nick within the conserved sequence 5'-AGTATTAC-3' in the intergenic region of the genome, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, and nucleotidyl transferase.
What are the official names of this protein?
Replication-associated protein, Rep, ATP-dependent helicase Rep, RepP.
What is the protein family that this protein belongs to?
Belongs to the nanoviruses/circoviruses replication-associated protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CAP3_ADE05
Sequence: MMQDATDPAVRAALQSQPSGLNSTDDWRQVMDRIMSLTARNPDAFRQQPQANRLSAILEAVVPARANPTHEKVLAIVNALAENRAIRPDEAGLVYDALLQRVARYNSGNVQTNLDRLVGDVREAVAQRERAQQQGNLGSMVALNAFLSTQPANVPRGQEDYTNFVSALRLMVTETPQSEVYQSGPDYFFQTSRQGLQTVNLSQAFKNLQGLWGVRAPTGDRATVSSLLTPNSRLLLLLIAPFTDSGSVSRDTYLGHLLTLYREAIGQAHVDEHTFQEITSVSRALGQEDTGSLEATLNYLLTNRRQKIPSLHSLNSEEERILRYVQQSVSLNLMRDGVTPSVALDMTARNMEPGMYASNRPFINRLMDYLHRAAAVNPEYFTNAILNPHWLPPPGFYTGGFEVPEGNDGFLWDDIDDSVFSPQPQTLLELQQREQAEAALRKESFRRPSSLSDLGAAAPRSDASSPFPSLIGSLTSTRTTRPRLLGEEEYLNNSLLQPQREKNLPPAFPNNGIESLVDKMSRWKTYAQEHRDVPGPRPPTRRQRHDRQRGLVWEDDDSADDSSVLDLGGSGNPFAHLRPRLGRMF
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices.  Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets.  As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome.  During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3.
What are the official names of this protein?
Pre-hexon-linking protein IIIa, Capsid vertex-specific component IIIa, CVSC, Protein IIIa, pIIIa.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein IIIa family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Surrounds the border of each facet on the capsid exterior. Present in around 60 copies per virion.
Protein: ATPE_SHEB5
Sequence: MAAMTVHLDIVSAESKIFSGRVVSLQVTGSEGELGIMHGHAPLLSYIKPGMARIVKQDGSEEVFYLSGGILEVQPSTVSVLADVVMRAKDIDEQAALEAKRRAEAHMANAGADFNYDAAMVELAKAMAQLRVVETIKKNIAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.