PharMolix/UniProtQA huggingface dataset:
Protein: SYA_MYCBP
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLGQRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWNLVFMQNERGEGTTKEDYQILGPLPRNNIDTGMGVERIALVLQDVHNVYETDLLRPVIDTVARVAARAYDVGNHEDDVRYRIIADHSRTAAILIGDGVSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPELVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDAFTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKHAHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHGVAGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADFEVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSNTAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRLVAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAEGESQTVPYAVAANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALDAVRSEIAVIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_HAHCH
Sequence: MLPHTISEIISGLRDKQFSSREITQDYLARIKRLNPELNCFITVTEDLALSQAEQADARLNAGQTSVLNGVPLAHKDVFCTEGVTTTCGSRMLEKFVPPYESTVTRKFIDAGAVTLGKTNMDEFAMGSSNENSYFGPVRNPWDTERAPGGSSGGSAAAVAAGLCAAATGTDTGGSIRQPAAFCGLTGLKPTYGRVSRLGMVAFASSLDQGGPFARTAEDAALLLNVMAGHDPMDSTSALNPTEDYTSALAQPLAGVTIGLPKEYFSNQLNAEVEKALQEAIKVYESLGASFKEVSLPHTELSVPAYYVIAPAECSTNLSRFDGVRYGHRCENPKDLEDLYQRSRSEGFGDEVKRRILIGTYALSAGYYDAYYRQAQKIRRLIKNDFVSALNEVDALLCPTTPDVAFRLGEKTSDPVQMYLEDIFTIPASLAGLPALGLPCGFKGGLPVGMQLIGNYFTEARLLNLGHQYQLNTDWHKRSPALGE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MOMP6_CHLP6
Sequence: MKKLLKSALLFAATGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCATWCDAISIRAGYYGDYVFDRVLKVDVNKTFSGMAATPTQATGNASNTNQPEANGRPNIAYGRHMQDAEWFSNAAFLALNIWDRFDIFCTLGASNGYFKASSAAFNLVGLIGFSAASSISTDLPMQLPNVGITQGVVEFYTDTSFSWSVGARGALWECGCATLGAEFQYAQSNPKIEMLNVTSSPAQFVIHKPRGYKGASSNFPLPITAGTTEATDTKSATIKYHEWQVGLALSYRLNMLVPYIGVNWSRATFDADTIRIAQPKLKSEILNITTWNPSLIGSTTALPNNSGKDVLSDVLQIASIQINKMKSRKACGVAVGATLIDADKWSITGEARLINERAAHMNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YCHF_BUCBP
Sequence: MGFKCGFVGLPNVGKSTLFNYLTKLNIPADNYPFCTIKSNVGIVPVLDNRLNKIAQVVCSNKIIPATIELVDIAGLVKGAYKGEGLGNQFLDHIRDTNVIMHIVRCFENRYVTHIYGSVDPVRDVQIINLELILSDIEVCKNRMCKLEINKLSHNKQVNKELLILKKCVYHLEKSKSLRSLNLTEEEIFVINYLRLITLKPVVYIFNISIDQSRNLYKREIFDIIKNEHNAKTVNVCLDLMQSSKNDVSAYDHLSLKYKQLFNKMLKNVIWAGFNALNLITFFTAGKKEVHAWTTTNNLFIFQSVKCIHTDLSKGFIRAQVISYDDFIKYKGEKRSKELGKIRIEGKRYVICDGDIIHVLYNV
What is the function of this protein?
ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
What are the official names of this protein?
Ribosome-binding ATPase YchF.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
Protein: RL6_ALBFT
Sequence: MSRIGKMPVAVPAGVDVLVKDDQISVKGAGGSLFLTQNALVKVSSDAGALSFQPANDSREANAMSGTMRQLVNNMVVGVTKGFEKKLNLVGVGYKAQAQGAKLNLTVGYSHPVNKDMPAGITVATPTPTEIVIKGADRQRVGQVAAEIRAIRPPEPYKGKGIRYSDEKITIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RNH2_SHEPC
Sequence: MAVFKVLTPADIVAFSTGLIAGVDEVGRGPLVGDVVTAAVILDPNQPISGLNDSKKLSEKRREALFDEICEKALCYHIGRASPAEIDELNILHATMLAMQRAVAGLNLAPKLVLVDGNRSPFFSHNSQSIVSHSIIKGDGLIASISAASIIAKVTRDREMDALDAAYPQYGFAKHKGYPTKAHFEAIAEHGVFDQYRKSFKPVKALLEG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_ARTS2
Sequence: MSDNNVMSDLEIAQRATMRPIGDIAAAAGINADAVELYGRYKAKIDPAKLIDPAGAPKRLPGKVVLVSAMSPTPAGEGKSTTTVGLADSLARAGRNVMIALREPSLGPVLGMKGGATGGGYSQVLPMEEINLHFTGDFHAITSANNALMALVDNHIFQGNELNIDPRRMTFKRVLDMNDRSLREVIIGLGGPAQGVPRQDGFDITVASEIMAVFCLATDIADLRARLGRITFGYTYDREPVTVADLGVQGALTMLLRDAIKPNLVQTIAGTPALVHGGPFANIAHGCNSLIATQTARRLADIVVTEAGFGADLGAEKFMDIKARVAGVAPSAVVLVATVRALKMHGGVAKDRLQEPNVEALAAGSANLRRHIRNVEKFGITPVVAVNKFATDTPEELDWLLEWCAGEGVQAAVADVWGRGGGGDGGDELAAKVLAALEAPHSFRHLYPLELSVEDKIRTIVQEMYGADGVDFSVPALKRLAEIEKNGWAGMPVCMAKTQYSFSDDATRLGAPKGFTVHVRDLIPKTGAGFIVALTGAVMTMPGLPKVPAALRMDVDDTGKPLGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CCDC8_RAT
Sequence: MLQIGEDVDYLLIPREVRLAGGVWRVISKPATKEAVFRERLIQFLQEEGRTLEDVARIIEKSTPHPPQPPKKAKVPRVRRVPQMVTPPLRLVVGTYDSSNGSDSELSDFDTSKVKGNRGSGKTRKVRKMPVSYLGSKFLGSDESEDDQELVEAFLRRGEKKPSAPPPRRRVNLPVPMFENNLGPQPSKGDRWREYVSQVSWGKLKQRVRGWAPRSGSEVGQAQQSSIAERAGEMRHSHTSPDLDDSSRNTGDLSDQTLITRRWKPKIKWVSLRRCRKEQVPPLAHGTAEEPPEAAENQGAGAAAEHGVEAAASQRPEAAASPRAEAAANPRAEATANPRAEAAANPRAEAAASPRAEAAANPRAEAAANPRAEATANPRAEAAANPRAEATANPRAEAAVNPRTEAAVNPRTEAAANPRAEAAVNPRAEATASPRAEAEVNQKTEATASPRAETAASPRVEAAASLRVEAAASPRAEATVSPRAEAVATPRAETAASARVEAAANLRAGVLPDQRAEAIDSQRAEGPVNQSTGATENQRVEVLADQRAGVLHDQREEAGPQAILEASADSGSRARKQVKTVRFQTPGRFSWFHMRRKAFWHTPRLPTLPKRGPRAGAGEARSLRVLRADTRADMEHREQEEQL
What is the function of this protein?
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity.  It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer.  Required for localization of CUL7 to the centrosome.
What are the official names of this protein?
Coiled-coil domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SURE_AZOVD
Sequence: MRILIANDDGALAPGIAALHDALADMAECVVVAPIKDMSGVSGSLTLDRPLHPQLLSNGFIALDGTPTDCVHLGLNGLLDPVPDMVVSGINLGANLGDDVLYSGTVAAAIEGRFCKRPAFAFSLLSREPDNLPAAAHIARTLVEHHERLALPPRTVLSVNIPNLPLERIRGIRLCRLGHRARAKAPVKMVNPRGKEGYWISVAGDAEDGGPGTDFHAVMQGYVSITPLQLDRTFHEAFAGLDSWLEDLL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_BACCN
Sequence: MKTNDIRELTTAEIETKVKALKEELFNLRFQLATGQLENPTRIREVRKAIARMKTVVREREIGINR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ATPB_STRPJ
Sequence: MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAFRGVGSIEDVIAKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRPA_BACFR
Sequence: MNRINQLFDSNPRDLLSIYFCAGYPTLEGTTEVIRTLEKHGVNMIEIGIPFSDPMADGMVIQNAATQALRNGMSLRLLFEQLHDIRRDVKIPLILMGYLNPIMQFGFDNFCRQCAECGIDGVIIPDLPFKDYQEHFRTIAERYDVKVIMLITPETSEERVREIDEHTDGFIYMVSSAATTGAQQDFDGQKRAYFKKIEKMNLRNPRMVGFGISNEATFRAACENASGAIIGSRFVTLLHEEKNPEKAITRLKAILNLSSNDLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CHED_ALKCK
Sequence: MTKGETISIGEWKVVKGEGVLRTCGLGSCIGIVLYDQERVIAGMVHVMLPDSTKARKGANPWRYADTAIASLQAELKKQGARKLCAKMAGGAQMFKHAVKREFMQIGERNAAAARETLARLGITLVAEDIGGTKGRTIQYDVKTGELAVRTVHHGQMIL
What is the function of this protein?
Deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs).  CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase (By similarity).
What are the official names of this protein?
Chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: RECF_LISMO
Sequence: MHLESIVLRNFRNYENLELEFSPSVNVFLGENAQGKTNLLEAVLMLALAKSHRTTNDKDFIMWEKEEAKMEGRIAKHGQSVPLELAITQKGKRAKVNHLEQKKLSQYVGNLNVVIFAPEDLSLVKGAPGIRRRFLNMEIGQMQPIYLHNLSEYQRILQQRNQYLKMLQMKRKVDPILLDILTEQFADVAINLTKRRADFIQKLEAYAAPIHHQISRGLETLKIEYKASITLNGDDPEVWKADLLQKMESIKQREIDRGVTLIGPHRDDSLFYINGQNVQDFGSQGQQRTTALSIKLAEIDLIHEETGEYPVLLLDDVLSELDDYRQSHLLGAIEGKVQTFVTTTSTSGIDHETLKQATTFYVEKGTVKKS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETDB_HUMAN
Sequence: MDKEVPKGSPREPALNIKKSDKSFKRKKPTENVLIFLINRQLGRHRSDIDLSRWVWMLS
What are the official names of this protein?
Embryonic testis differentiation protein homolog B.
Protein: BH143_ARATH
Sequence: MPLDTKQQKWLPLGLNPQACVQDKATEYFRPGIPFPELGKVYAAEHQFRYLQPPFQALLSRYDQQSCGKQVSCLNGRSSNGAAPEGALKSSRKRFIVFDQSGEQTRLLQCGFPLRFPSSMDAERGNILGALHPEKGFSKDHAIQEKILQHEDHENGEEDSEMHEDTEEINALLYSDDDDNDDWESDDEVMSTGHSPFTVEQQACNITTEELDETESTVDGPLLKRQKLLDHSYRDSSPSLVGTTKVKGLSDENLPESNISSKQETGSGLSDEQSRKDKIHTALRILESVVPGAKGKEALLLLDEAIDYLKLLKQSLNSSKGLNNHW
What are the official names of this protein?
Transcription factor bHLH143, Basic helix-loop-helix protein 143, AtbHLH143, bHLH 143, Transcription factor EN 129, bHLH transcription factor bHLH143.
What are the subcellular locations of this protein?
Nucleus.
Protein: TGT_THEAB
Sequence: MGLKFELLKTSGNARRGRIYLPHGVVETPTFMPVGTNANVKLMTPKLLDEIGAQIILGNAFHLYLKPGLDVFRFHGGIHNFMNWQKPVLTDSGGFQVFSLREGRKITEDGVLIRSPLDGSKHMITPELSMEIQHAIGSDIVMAFDYCAEPGISHQDAVVALELTSLWAERSLKKLRSLSDQAIFGIVQGAFFKDLRLRSAKEITSMNFDGFAIGGLSVGEEYDITLDMTKFTAPLLPENKPRYFMGAGSPKLIVDLVDSGIDMFDSVLPTRVARHGQALTWKGKLNIRSAKYKFSKEPIDESCGCYTCKNFSRSYIRHLFDRGEVLGQILLTIHNLHFMMDLSKKIRESIENDTFQELRGEVLKYYA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ACPS_BURO1
Sequence: MAIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVVAETDAETDAAPAPVPVSRTSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
Protein: TRMB_BACSU
Sequence: MRMRHKPWADDFLAENADIAISNPADYKGKWNTVFGNDNPIHIEVGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTDVFEPGEVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNRGLFEYSLKSFSEYGLLLTYVSLDLHNSNLEGNIMTEYEEKFSALGQPIYRAEVEWRT
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, BsTrmB, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ASNA_YERPB
Sequence: MKKQFIQKQQQISFVKSFFSRQLEQQLGLIEVQAPILSRVGDGTQDNLSGSEKAVQVKVKSLPDSTFEVVHSLAKWKRKTLGRFDFGADQGVYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERNLAYLKSTVNKIYAAIKETEAAISAEFGVKPFLPDHIQFIHSESLRARFPDLDAKGRERAIAKELGAVFLIGIGGKLADGQSHDVRAPDYDDWTSPSAEGFSGLNGDIIVWNPILEDAFEISSMGIRVDAEALKRQLALTGDEDRLELEWHQSLLRGEMPQTIGGGIGQSRLVMLLLQKQHIGQVQCGVWGPEISEKVDGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_HALHL
Sequence: MRVLFATAEAWPLAKTGGLGDVAFGLTRALAELDCDVRLLMPAYPGTVEQLEGEVRRHTAELAGEGVTLIEGRLPGTGVGVWLLDDPPLFARVGGPYATAGGDAWPDNHWRFLRLSQVAAALAAGDLLDWRAEVLHGNDWQTALAPVFLRDRADRPATVFGIHNLAYRGLFPAELYPRLGLPAELWQPEGLEFYGQLAFIKGSLVFADTLVTVSPTYAREIQTPAFGWGLDGLLHHRRDRLFGIVNGIDTATWDPGSDRHLVAQYTGPDDRARAANRRAVARAVGLSEGEGPILGFVGRLVEQKGVDLILAALPRLLAAGAQLALLGAGDHRLETALRAAAEQHPGQVGVVIGYDEALAHQIEAGSDLFLMPSRFEPCGLNQLYSLRYGTPPVVYPTGGLADTVVDVDAHPQSGNGFHLAASDGAALAAAVERALAHWQDRPTWHAIQARGMAGTYSWAASAQAYQDLYRQVVASRG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: HGD_RHOP5
Sequence: MNINTVPELIGRGSASITPGYMSGFKNSFETEALPGALPIGRNSPQRCAYGLYAEQLSGSPFTAPRGSNERSWLYRIRPSVKHSGRFAKADVGLWRTAPCHEHEMPIAQLRWDPPPLPQHEQTFLQGVVTMTTAGDANTQAGMAAHIYLITASMVDQAFYNADGELMFVPQQGSLRFVTEFGRIDAGPGEIVVIPRGVKFRVELTGGPARGYLCENYGGAFTLPERGPIGANCLANARDFLTPVAAYEDKDTPTELFVKWGGTLWATTLPYSPIDVVAWHGNYAPYKYDLRTFSPVGAIGFDHPDPSIFTVLTAPSETPGTANIDFVIFPERWMVADNTFRPPWYHMNIMSEFMGLIYGVYDAKPQGFVPGGASLHNMMLPHGPDREAFDHASNGELKPTKLTGTMAFMFETRYPQRVTEYAATSGLLQPDYADCWTGLEKRFDPTRP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: ARCA_STAEQ
Sequence: MTNGPIQVNSEIGKLKTVLLKRPGKELENLVPDYLDGLLFDDIPFLKVAQQEHDHFAQVLQDEGIEVLYLEKLAAQSIEDSNVREQFIDDVLAESRKTILGHEKEIKKLFSTLSNQALINKIMAGVRKEEIQLESTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGRGMTVNRMFWRARRRESIFISYILKHHPRFKDENIPLWVDRDCPFNIEGGDELVLSKDVLAIGISERTSAQAIERLARRIFKDPLSTFKKVVAIEIPTSRTFMHLDTVCTMIDYDKFTTHSAILKSEGNMNIFIIEYDDKAEDIKIQHSSHLKQTLEEVLDVDEITLIPTGNGDIIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNQLLREHGIKVIEIPGSELVRGRGGPRCMSQPLIREDL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFA1A_MOUSE
Sequence: MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRLEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKREREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome.
What are the official names of this protein?
Microfibrillar-associated protein 1A, Spliceosome B complex protein MFAP1A.
What is the protein family that this protein belongs to?
Belongs to the MFAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISG15_MOUSE
Sequence: MAWDLKVKMLGGNDFLVSVTNSMTVSELKKQIAQKIGVPAFQQRLAHQTAVLQDGLTLSSLGLGPSSTVMLVVQNCSEPLSILVRNERGHSNIYEVFLTQTVDTLKKKVSQREQVHEDQFWLSFEGRPMEDKELLGEYGLKPQCTVIKHLRLRGGGGDQCA
What is the function of this protein?
Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein.  ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein.  Its target proteins include SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, TRIM25, STAT5A, MAPK1/ERK2 and globin.  Isgylation of the viral sensor IFIH1/MDA5 promotes IFIH1/MDA5 oligomerization and triggers activation of innate immunity against a range of viruses, including coronaviruses, flaviviruses and picornaviruses.  Can also isgylate: RIGI which inhibits its function in antiviral signaling response, IRF3 which inhibits its ubiquitination and degradation as well as EIF4E2 which enhances its cap structure-binding activity and translation-inhibition activity.  Exhibits antiviral activity towards both DNA and RNA viruses, including influenza A and B virus, sindbis virus (SV) and herpes simplex type-1 (HHV-1).  Plays a significant role in the control of neonatal Chikungunya virus (CHIKV) infection by acting as a putative immunomodulator of pro-inflammatory cytokines.  Protects mice against the consequences of Chikungunya virus infection by down-regulating the pathogenic cytokine response, often denoted as the cytokine storm.  Plays a role in erythroid differentiation.  The secreted form of ISG15 can: induce natural killer cell proliferation, act as a chemotactic factor for neutrophils and act as a IFN-gamma-inducing cytokine playing an essential role in antimycobacterial immunity.  The secreted form acts through the integrin ITGAL/ITGB2 receptor to initiate activation of SRC family tyrosine kinases including LYN, HCK and FGR which leads to secretion of IFNG and IL10; the interaction is mediated by ITGAL (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ISG15, Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Exists in three distinct states: free within the cell, released into the extracellular space, or conjugated to target proteins.
Protein: AB19G_ARATH
Sequence: MNLSLSGRKIAMTRVSAETQYITPIGSPTLDELLKDCDSFRKGDSGDGVKSDDPAHHIIDVEALYVKPVPYVLNFNNLQYDVTLRRRFGFSRQNGVKTLLDDVSGEASDGDILAVLGASGAGKSTLIDALAGRVAEGSLRGSVTLNGEKVLQSRLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPRSLSKSKKMERVEALIDQLGLRNAANTVIGDEGHRGVSGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTNAFMVVQVLKRIAQSGSIVIMSIHQPSARIVELLDRLIILSRGKSVFNGSPASLPGFFSDFGRPIPEKENISEFALDLVRELEGSNEGTKALVDFNEKWQQNKISLIQSAPQTNKLDQDRSLSLKEAINASVSRGKLVSGSSRSNPTSMETVSSYANPSLFETFILAKRYMKNWIRMPELVGTRIATVMVTGCLLATVYWKLDHTPRGAQERLTLFAFVVPTMFYCCLDNVPVFIQERYIFLRETTHNAYRTSSYVISHSLVSLPQLLAPSLVFSAITFWTVGLSGGLEGFVFYCLLIYASFWSGSSVVTFISGVVPNIMLCYMVSITYLAYCLLLSGFYVNRDRIPFYWTWFHYISILKYPYEAVLINEFDDPSRCFVRGVQVFDSTLLGGVSDSGKVKLLETLSKSLRTKITESTCLRTGSDLLAQQGITQLSKWDCLWITFASGLFFRILFYFALLFGSRNKRT
What is the function of this protein?
Confers selective resistance to kanamycin.
What are the official names of this protein?
ABC transporter G family member 19, ABC transporter ABCG.19, AtABCG19, White-brown complex homolog protein 19, AtWBC19.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RS6_HAEDU
Sequence: MRHYEIVFMVHPDQSEQVPAMIERYTASVTEAGGQVHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPKSVIDELETNFRYNDAVLRNLIVHTKAAVKEASLMAKAKESKTTEVVAEVESKEASE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.