PharMolix/UniProtQA huggingface dataset:
Protein: FUCP_HAEIN
Sequence: MNAKVLEKKFIVPFVLITSLFALWGFANDITNPMVAVFQTVMEIPASEAALVQLAFYGGYGTMAIPAALFASRYSYKAGILLGLALYAIGAFLFWPAAQYEIFNFFLVSLYILTFGLAFLETTANPYILAMGDPQTATRRLNFAQSFNPLGSITGMFVASQLVLTNLESDKRDAAGNLIFHTLSEAEKMSIRTHDLAEIRDPYIALGFVVVAVFIIIGLKKMPAVKIEEAGQISFKTAVSRLAQKAKYREGVIAQAFYVGVQIMCWTFIVQYAERLGFTKAEGQNFNIIAMAIFISSRFISTALMKYLKAEFMLMLFAIGGFLSILGVIFIDGVWGLYCLILTSGFMPLMFPTIYGIALYGLKEESTLGAAGLVMAIVGGALMPPLQGMIIDQGEVMGLPAVNFSFILPLICFVVIAIYGFRAWKILK
What is the function of this protein?
Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-fucose-proton symporter, L-fucose-H(+) symport protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRM3_MOUSE
Sequence: MAAPAKGMWCSLGSLLRVVQTRDLNARRWVRALRRSPVRVLSPSGQVEERKRAPDQQPRKAVPKASSQGQRQKQPLETSPSQTPHTWEEAGLRYDKAFPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLIADALKAGAVPKAFFFSRLEYVKELPVDKLKDVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDPVKMTYPETPLHHTLPLVLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHLPPDTRVYVADNCGHYAQVQMSDKTGDRDWACDRRFLKFHKYEEDLDTKTRKDWLPKLEVQSYDLDWTGAPAAVVIGGETHGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRIKVEDLSRDRSYH
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 3, mitochondrial, 16S rRNA (guanosine(1370)-2'-O)-methyltransferase, 16S rRNA [Gm1370] 2'-O-methyltransferase, RNA methyltransferase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EXP13_ARATH
Sequence: MQRFLLPLLFLALSPPAICHYSSSTSSPSSSSVSSDASEWRPARATYYAATNPRDAVGGACGYGDLVKSGYGMATVGLSETLFERGQICGACFELRCVDDLRWCIPGTSIILTATNFCAPNYGFDPDGGGHCNPPNKHFVLPIEAFEKIAIWKAGNMPVQYRRINCRKEGSMRFTVDGGGIFISVLITNVAGSGDIAAVKIKGSRTGWLPMGRNWGQNWHINADLRNQALSFEVTSSDRSTVTSYNVSPKNWNYGQTFEGKQFETP
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A13, AtEXPA13, Alpha-expansin-13, At-EXP13, AtEx13, Ath-ExpAlpha-1.22.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: 5DNU_ECO27
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAKEYKAIEKIAQQKLVDMVPEELQDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_GLUOX
Sequence: MEPAMPEHDGDHASNPPHGVGIPNDSAGIVQTIEQARSEGHTHEIGGGEEGSGHERPAGMGALLAVLGVVYGDIGTSPLYALQSSVSIVSSPKAPAQPWEIMGLASLTFWALMLIVTIKYVILIMRADHDGEGGIIALMSLAQRVCKSQHFRWLFGLVGIAGTCLFFGDSIITPAISVLSAVEGIETSVPSASHIIIPLAMVVLVALFSVQVLGTGKIGKAFGPIMVCWFSVLAILGIKGIFLYPHILLALSPTFALEFIVLHGYLSFIALGSVVLSVTGAEALYADMGHFGRAPIRKAWLFFVLPSLTLNYFGQAALLIRDPHALSNPFYLLVPHWAQIPMLVLATFATVIASQAGISGSFSLCRQLIQLGYLPRTRIMHTNASEEAQIYLPSLNWILAFGALVLVLAFRTSSALAAAYGIAVTGTFLCTCVLAMVVFRRVFKWKSATVAIVFGFFFIVDSIFFSANVLKIPDGGWVPLAIGIISTIIMTTWKRGRSLIAARQQADSMPMGSFLARLPQSRTIRVPGLAVFLTANPDIVPNSLLHNLKHNKVLHDHILFVTVENLDQPEAERGHRAIVQELAPNIHRVIVRYGFMEMPNLPRALLELNALGVAFDAIQASYFTSHELVVRSRVPKMQLWRMWIFLFLLRNAASTTEFLRIPPDRVVEFGVRIAI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS21_XENTR
Sequence: MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQINIAEVDKVTGRFNSQYKTYAICGAIRRMGESDDSILRLAKNDCIVSKNF
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: RL1_BAUCH
Sequence: MGKTTKRMRMISNQIDRTKQYNIHEAIPLLKDHATVKFIESLDVAVKLGINARKSSQNIHSATILPHGIGRSIKVAVFAQGINVSIAETAGADLVGMDNLAAQITKGNINFDVVIASPDTMHLVSTLGQILGPKGMMPNTKTGTITQNIALAIKEIKSGQIRYHNDKNGIIHTTIGKINFESYQLIENLEALLRALKKDKPLQTKGIYFKKICLSTTMGPSLTIDQCSLSTLVK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HIS4_CALS4
Sequence: MLVIPAIDILDGKCVRLTKGNFDSKEVYYDNPADMAKMWQECGAKRIHVVDLDGARQGHLVNRKVIEKIVNSCSVDIEVGGGIRNKEALDYLFSIGVSYIILGSAAIYDKDLLLYSVSHYGEKTIVGIDSKKREVAVSGWLERTKIKDTELAEKIKEIGIKTIIFTDISKDGTLHGPNFEALKDMLKVGVEIIASGGISSIEDLKRLKDMGVTGAIIGKALYTGMIDLKAALLELEREGI
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_OENEH
Sequence: MIWHVQNENLILDSTRIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRPB_MYCTU
Sequence: MTDLSTPDLPRMSAAIAEPTSHDPDSGGHFGGPSGWGGRYVPEALMAVIEEVTAAYQKERVSQDFLDDLDRLQANYAGRPSPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTRVIAETGAGQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAEVVAVQTGSKTLKDAINEAFRDWVANADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVACVGGGSNAIGIFHAFLDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLLQDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIPAIESAHAVAGALKLGVELGRGAVIVVNLSGRGDKDVETAAKWFGLLGND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LPXD_ELUMP
Sequence: MQISLEELVKITGGELRGNKDFQITAPCSIDNPKEDAVCYFSDGSKAESISSIKAGCFILPSKIKETFKTDKNVIFADNPEWAFTLFLRHYDSSKPKFDRGVHPTAVIGKNVVLGNNITVGAYSVIEDDVTLGDNTVIYPHVYIGRRTFVGKDCILYPNVVVREECIIKDRVIIEAGATIGTDGFGFVLVNYKHEKIPQVGNVIIESDSEIGANTTIDRAKIDSTVIGVNVKVDNLTQLAHNVKVGQGSIIISQVGVAGSTEIGRGVVLAGQVGVAGHIKIGDGVQVGAQSGIMQDIPAGKKMFGTPVRDYMETLKLYAALPYLSEMVREFRKRKKTEENK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: FAH_ORYSJ
Sequence: MAEGSRSPLRSFVEVAPGSHFPIQNLPFGVFRRRGSPEPEPPRPAVAIGDFALDLAAVSDAGLFHGPLLSASPCFRQETLNMFLGMGRPAWKEARATLQKILSADEPVLRDNEALKKKCLVPMSDTEMLLPITVGDYTDFFCSVHHARNCGFIFRGPQTPVNPNWFQLPVGYHGRASSVIVSGTDIIRPKGQGHPTGDSRPYFGPSKKLDFELEMAAIVGPGNELGKPIDINDAEEHIFGLMIMNDWSARDIQAWETIPLGPFLGKSFSTTVSPWIVTMDALKPFTCEAPKQEPEPLPYLAEKNHVNYDIPLEVWIKPKEQSEPSMVAKSNFKHLYWTLTQQLAHHTVNGCNLRPGDMFATGTLSGPETESLGCLLELTWNGQKEISVGNSTRKFLEDGDEVILTACCKGEGYNVGFGTCTGKVLPALP
What is the function of this protein?
Converts fumarylacetoacetate to acetoacetate and fumarate.  Involved in tyrosine catabolic pathway.  Catalyzes the final step in the tyrosine degradation pathway.
What are the official names of this protein?
Fumarylacetoacetase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: ADEC_METNO
Sequence: MPAEIARRIAQGAGREPADLVIRGARLLDLVTGELVPTDIAVCGEVVVGTYGEYEGARVIEAASRIAVPGFIDTHLHIESSLITPHEFDRCVLPHGVTTAIWDPHELANVLGTAAFDYALQASTETAMDIRVQLSSCVPATDLESAGARIEAADLLPYRDHPRSLGIAEFMNFPGVVQADPGCLAKLAAFAGRHVDGHAPLLSGSGLNAYAAAGIRTDHEATGAAEALEKIRKGMTVLIREGSVSKDLAALAPLLTVATSPFLAFCTDDRNPLDIAEEGHLDHLIRTAIRLGVPPLAAYRAASLSAATAFGLTDRGMIAPGRRADIVLLDDLEACAVARVIAGGRAVEEALFAGRARTPAPGRGSVKAAPVAAEDFRIPGADGAETSVIGVVPGRIITEHRRLELPAANGCAGCDLDQDVVKVAVIARHGRPGMGRGFVQGFGLRRGAIASSVGHDSHNLCVVGADDADMAVAINRLIALQGGFVVAAGGTVLAELALPIAGLMSDLPFEAVRDALHPLREAARTLGCTLPEPFLQVAFLPLPVIPHLKITDRGLVDVDRMRLLG
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RM51_CHICK
Sequence: MAALVRGLMRRVAALPQAVRSVSGGGQRHEPYRPLPITSPLAGLPRNFRVREPPKPQKVDRWTEKRALFGVYDNVGILGGFQIHPKHLIMGPKWLRGWRGNELQRCIRKKQMVGDRMFMDDYHNLKKRIRFLYKRFNRTGKHR
What are the official names of this protein?
39S ribosomal protein L51, mitochondrial, L51mt, MRP-L51.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL51 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TSAD_CHLP8
Sequence: MNILGIETSCDETSAAVLSDGTVRSNVVSSQRCHTDFGGVVPELASREHERLIVSIVEAAITEANIAKNDLDVIAATAGPGLIGAVMVGLCFAEGMAFALGKPFVPVNHVEAHIFSPFISDEPGHKSPDGDFVSLTVSGGHTLLSVVRQNLDYEVIGRTIDDAAGEAFDKTGKMLGLGYPAGPVIDRLARDGDPKFHRFPRALTSSSQTSKSYRGNFDFSFSGLKTSVRTWLEGHDAEFARQHQTDLAASIQDAIVSVLVEKTIAAALLHKVGAVSVAGGVSANSGLRSAMQAACNKHGLDLFIPKATYSTDNAAMIATMAQLMMARGRYRENSYGVAPFARFKAAGKGTR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_BRUC2
Sequence: MNDETTPANKNPEKAELRCGWTTGACATAATKAALTALITGEFPDPVGIILPKGEVPYFQLAYEGLGEGYAMAGIVKDAGDDPDVTHGATIISTVYPAPPGTGIIFRAGEGVGTVTREGLAIPPGEAAINPVPRRMMTEICEAICAEYGLPADLVITISVPGGEEIAQKTWNPRLGIIGGISILGTTGVVHPFSCSAWIHSIHRGIDVARAAGQKHVLGATGSTSEDAAQALYNLPDFAILDMGDFAGGVLKYLREHPIDRLTIAGGFAKLTKLAQGALDLHSSRSQVDKGFLWQIAERAGAPADMKERILLANTAMEVLELTQSIGIDIAGPIALEARQTALKTLRGAPVEVEIIVTDRKGNILARV
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: FEN1_ARATH
Sequence: MGIKGLTKLLADNAPSCMKEQKFESYFGRKIAVDASMSIYQFLIVVGRTGTEMLTNEAGEVTSHLQGMFNRTIRLLEAGIKPVYVFDGKPPELKRQELAKRYSKRADATADLTGAIEAGNKEDIEKYSKRTVKVTKQHNDDCKRLLRLMGVPVVEATSEAEAQCAALCKSGKVYGVASEDMDSLTFGAPKFLRHLMDPSSRKIPVMEFEVAKILEELQLTMDQFIDLCILSGCDYCDSIRGIGGQTALKLIRQHGSIETILENLNKERYQIPEEWPYNEARKLFKEPDVITDEEQLDIKWTSPDEEGIVQFLVNENGFNIDRVTKAIEKIKTAKNKSSQGRLESFFKPVANSSVPAKRKEIPESTTKGAANKKTKGAGGRKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: POL1_BAYMY
Sequence: MEQTLAQAVSRRNKTDTPMAEERKHFSPMNFSANFVAPELFYSANVRKIKNIFKERSTTRFLDAISSDFELVAFLTLSPAHLMQLETVLRQEMRSCAVPIVTSDASFETVAVIKTALDGMRFHFGYTTLEKGWISMMRHAESCLQESSSSAVNDLQTPIKRVGSLLLSGKNRVEGCELSVLNLTARRFRIEYGLNGTYFGEHVAMLRDLKRYIYGTVPKEFLWAKTKKHLPFTIPAWITRTPIDCFLFCLRVIPILHRFGVAMSLIYFSCVAALNFPAFMGFLFKRQFAKYLAHSFAKHSIYFMFLTIVAILWSFRTFTSQKPKIVLQARSTAEKEKKLMMILASVVGITYLFDYDIAEALGNCLHKISRLSSYLLDDHQGIASRMFGASYGLQAGDSAEDAVTTIISDLLSVTFKIVDEDASQGTVEDASETTFHSWVGVNTLAGRNMSRPLQYSVNKTYALTPQNVQLQARAMADANNCWSMVVGHTGSGKSTYLPVQYSNYLSTKSDRRQQILICEPTQAATENVCAGVAANLGRAVYGRHEGWSRMGDHCIQVMTYGSALQCHAMDPSFISTFDAIFLDEAHDVKEHSLVFESICDTFKSVRKFYVSATPRDGSVCPEAARKYPLHVETSVCDSYRKFIAAQGGGDLLDISKHDTALVFLAGRPECIKAANAWNASVTGEKRAFSLSSDNFATDFSMLTERLKTHKTIIFTTNIIETGVTLSVDCVVDFGHTMRPCLDLNQKSLRLDRRKVTRNERQQRIGPTGRLKDGYAIVCGDVDRAVNVISPDVLYGAALLSFKHNVPFYMNETFESSWLKGVTKAQADTMTIFKLPIFLTRDLINADGSVAKEFLDVLKKHQFTTSDIKQAPSITAKHIFPTWASYFSLHQALHYGDDKDEIPHELRYARVPFSVTTLSKFDWPALALACEKHRASMSNVFAGIEEPARVVTLQTNPANIQASITHLMHMSKNYKTLIENNQHVRQSMMTNVMYKWFSSTRITKDLDRNLRRCTDNLAVVEATLSSLRQILAGNTQVHATPHMQSTLEDIIGLQASDTLTEESLASALGIFVPKSNLFLLLATKGFKLVYVICILLLVNLVYIGLRKWREHLKQKGSDEILTNTMPVSEGGEILAEVMKMEPKMRKNIKRDMDEAVESKLCGFTFVFPDDDKIGLEGKGNKYRPREDARLMYSTREDATFDAWNEKAKERRKKVTDKSEPELRRAYEKRPYFNFYDLQTDSNILEAIFYTTEGDEFFRTADPNKDMNLVADKLRSFLDTKLVVGHHQRKLLEETAQVVIKDTKGTAHKMEISQHDPDCLKQNGSGKVGYPEHRGQFRQEGVAITSDYDLGVEFGTDTDNITLEASTGILLSQVGVDVATRVGRISIGTFNMNCYFYNDWILVPGHLQDRSGNVTIQFPDQTVQTTTDALNANGVKRFYGLDVIAIRRPAILRPRTKLVKAFAIEEPVIAQMVFVDAQGVRKFTQSDWARKGENSGRWSHKISTVLGMCGCQFWTLERQIDGIHVATNYTKKRNEFQPFTQEVVDFINGPGTKIPYCPWVFDRPACGYASHTALFEKPTTLTDVIHMQASDGLHNINNAIEGFGSSLRGQLVSPPTESTRQRFDKLFGSGSFELIGQMNKGLIDKHVIVGENDDVYDFMREHPTFTWLKDFMNEYAPSVLSYSAYYKDLCKYNRAKHVLTYNPEELHYATKGLIKMLEDAGLTQGSVRTPQQVISDIQWNTSAGPSYQGKKRDLCAHLSDDEVLHLAEVCRQQFLEGKSTGVWNGSLKAELRTIEKVEPEKTRVFTASPITSLFAMKFYVDDFNKKFYATNLKAPHTVGINKFGRGWERLHDKLNRPGWLHGSGDGSRFDSSIDPFFFDVVKTIRKHFLPSEHHKAIDLIYDEILNTTICLANGMVIKKNVGTQRQPSTVVDNTLVLMTAFLYAYIHKTGDRELALLNERFIFVCNGDDNKFAISPQFDEEFGHDFSPELVELGLTYEFDDITSDICENPYMSLTMVKTPFGVGFSLPVERIIAIMQWSKKGGVLHSYLAGISAIYESFNTPKLFKSIYAYLLWLTEEHEAEILAAMTQSSTALPIPSMLDVYRLHYGDDEIWLQAADPLTDAQKEAAHTAAADRARLDLADADRRRKVEADRVEAARVKKAADAALKPVNLTATRMPTEDDGKLKTPSGARIPSSAADGNWSVPATKQVNAGLTLKIPLNKLKSVPKSVMEHNNSVALESELKAWTDAVRTSLGITTDEAWIDALIPFIGWCCNNGTSDKHAENQVMQIDSGKGAVTEMSLSPFIVHARMNGGLRRIMRNYSDETVLLITNNKLVAHWSMKHGASANAKYAFDFFVPRSWMNPQDIEVSKQARLAALGTGTYNTMLTSDTTNLRKTTNHRVLDSDGHPELT
What is the function of this protein?
An RNA-dependent RNA polymerase that plays an essential role in the virus replication.
What are the official names of this protein?
Genome polyprotein 1.
What is the protein family that this protein belongs to?
Belongs to the bymoviruses polyprotein 1 family.
What are the subcellular locations of this protein?
[6 kDa protein 1]: Host cytoplasmic vesicle. Note=Probably colocalizes with 6K2-induced vesicles associated with host chloroplasts. SUBCELLULAR LOCATION: [6 kDa protein 2]: Host cytoplasmic vesicle. Note=6K-induced vesicles associate with host chloroplasts. SUBCELLULAR LOCATION: [Capsid protein]: Virion.
Protein: NEP1_ARCFU
Sequence: MGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAMKSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRLPRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREKGGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSLYVTSRVLCEYERVRAHKVG
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: TYSY_YEAST
Sequence: MTMDGKNKEEEQYLDLCKRIIDEGEFRPDRTGTGTLSLFAPPQLRFSLRDDTFPLLTTKKVFTRGIILELLWFLAGDTDANLLSEQGVKIWDGNGSREYLDKMGFKDRKVGDLGPVYGFQWRHFGAKYKTCDDDYTGQGIDQLKQVIHKLKTNPYDRRIIMSAWNPADFDKMALPPCHIFSQFYVSFPKEGEGSGKPRLSCLLYQRSCDMGLGVPFNIASYALLTRMIAKVVDMEPGEFIHTLGDAHVYKDHIDALKEQITRNPRPFPKLKIKRDVKDIDDFKLTDFEIEDYNPHPRIQMKMSV
What is the function of this protein?
Thymidylate synthase required for de novo biosynthesis of pyrimidine deoxyribonucleotides.  Required for both nuclear and mitochondrial DNA synthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase, Cell division cycle protein 21, Constitutive RNR3 transcription protein 9.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to the nuclear periphery.
Protein: HSDA_SESIN
Sequence: MDLIHTFLNLIAPPFTFFFLLFFLPPFQIFKFFLSILGTLFSEDVAGKVVVITGASSGIGESLAYEYAKRGACLVLAARRERSLQEVAERARDLGSPDVVVVRADVSKAEDCRKVVDQTMNRFGRLDHLVNNAGIMSVSMLEEVEDITGYRETMDINFWGYVYMTRFAAPYLRNSRGRIVVLSSSSSWMPTPRMSFYNASKAAISQFFETLRVEFGPDIGITLVTPGFIESELTQGKFYNAGERVIDQDMRDVQVSTTPILRVESAARSIVRSAIRGERYVTEPAWFRVTYWWKLFCPEVMEWVFRLMYLASPGEPEKETFGKKVLDYTGVKSLLYPETVQVPEPKND
What is the function of this protein?
Has dehydrogenase activity against corticosterone (11 beta-hydroxysteroid) and estradiol (17 beta-hydroxysteroid), with higher activity against estradiol.  Possesses higher dehydrogenase activity with NADP(+) than NAD(+) regardless of the sterol substrate.  May be involved in signal transduction regulated by various sterols.
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase A, 17-beta-hydroxysteroid dehydrogenase A, Seed oil body protein 2, Steroleosin-A.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Single-pass type II membrane protein. Note=Surface of oil bodies. Exists at a monolayer lipid/water interface.
Protein: MRLCA_RAT
Sequence: MSSKRAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEAIGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
What is the function of this protein?
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation.  Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
What are the official names of this protein?
Myosin regulatory light chain RLC-A, Myosin RLC-A, Myosin regulatory light chain 2-A, smooth muscle isoform.
Protein: NU4LM_CALMU
Sequence: MTQASTNILLAFFFSLLGTLIFRSHLMSTLLCLEGMMLTLFIMSTMTALNSQSTVMYTIPIVMLVFAACEAAIGLALLAMISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MDH_SACS2
Sequence: MVKIAFIGVGKIGQTIAYSVIFDGLASEAILYDIVPELPEKFEHELRHAIATRGLSTEVIGTNSLDDVTNADIILIMAGKPRKPGMSRRDLFIDNAKIQIDLAKQLPPKNPGALYIMVANPVDMMASVFMRFSKQFTISTGDAVETMRLRSYIAKKLKVPANKVTGYVAGEHGEDAVVLWSTVKVNGKPFEEVAKGLTKEEVENYVKSIPGEIIRVMGGTTWGPATIIKDIVRSVVFNEGRVMSIATPRTYQGEIIHISVPIVVGAEIGPSLEGVLPESDRQRLNKSVEDFYRVYKENLDHLLQTVKQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.