PharMolix/UniProtQA huggingface dataset:
Protein: NUSB_SORC5
Sequence: MGARSTGREAALQMLFAVEAGGSSAPRVVATFWRETPGDPEGRAYADEVVVGVAEDLAAVDEAIRKASTNWRLERMARVDRNVLRLGAWELMNRPEVPRAVILDEAVELAKRYGSEESGAFVNGVLDRIAENLGRVDRDR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ISDH_STAA3
Sequence: MNKHHPKLRSFYSIRKSTLGVASVIVSTLFLITSQHQAQAAENTNTSDKISENQNNNATTTQPPKDTNQTQPATQPANTAKNYPAADESLKDAIKDPALENKEHDIGPREQVNFQLLDKNNETQYYHFFSIKDPADVYYTKKKAEVELDINTASTWKKFEVYENNQKLPVRLVSYSPVPEDHAYIRFPVSDGTQELKIVSSTQIDDGEETNYDYTKLVFAKPIYNDPSLVKSDTNDAVVTNDQSSSVASNQTNTNTSNQNTSTINNANNQPQATTNMSQPAQPKSSTNADQASSQPAHETNSNGNTNDKTNESSNQSDVNQQYPPADESLQDAIKNPAIIDKEHTADNWRPIDFQMKNDKGERQFYHYASTVEPATVIFTKTGPIIELGLKTASTWKKFEVYEGDKKLPVELVSYDSDKDYAYIRFPVSNGTREVKIVSSIEYGENIHEDYDYTLMVFAQPITNNPDDYVDEETYNLQKLLAPYHKAKTLERQVYELEKLQEKLPEKYKAEYKKKLDQTRVELADQVKSAVTEFENVTPTNDQLTDLQEAHFVVFESEENSESVMDGFVEHPFYTATLNGQKYVVMKTKDDSYWKDLIVEGKRVTTVSKDPKNNSRTLIFPYIPDKAVYNAIVKVVVANIGYEGQYHVRIINQDINTKDDDTSQNNTSEPLNVQTGQEGKVADTDVAENSSTATNPKDASDKADVIEPESDVVKDADNNIDKDVQHDVDHLSDMSDNNHFDKYDLKEMDTQIAKDTDRNVDKDADNSVGMSSNVDTDKDSNKNKDKVIQLNHIADKNNHTGKAAKLDVVKQNYNNTDKVTDKKTTEHLPSDIHKTVDKTVKTKEKAGTPSKENKLSQSKMLPKTGETTSSQSWWGLYALLGMLALFIPKFRKESK
What is the function of this protein?
Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin.  Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein H, Haptoglobin receptor A, Staphylococcus aureus surface protein I.
What is the protein family that this protein belongs to?
Belongs to the IsdH family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor.
Protein: MIND_ECOL6
Sequence: MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLRNLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGVAKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGILASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVLRASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG
What is the function of this protein?
ATPase required for the correct placement of the division site.  Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).
What are the official names of this protein?
Septum site-determining protein MinD, Cell division inhibitor MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS29_CANGA
Sequence: MAHENVWFSHPRRFGKGSRQCRVCSSHTGLIRKYDLNICRQCFRERASDIGFNKYR
What are the official names of this protein?
40S ribosomal protein S29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y838_STAAB
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGGTPYFKPLHMVLRLFMLLMLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPLSKLFGIG
What are the official names of this protein?
UPF0344 protein SAB0838.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CATA_VIBVU
Sequence: MHMSKSFLLISMGLASISVHAQTLTRDNGAPVGDNQNSITAGENGSVLLQDVHLIQKLQRFARERIPERVVHARGTGAHGEFVVSGDFSDLTLSSPFAQSGKVTPVFVRFSTVIHSKGSPETLRDPRGFATKFYTDQGNWDLVGNNLPVFFIRDSIKFPDMVHSLKPSPVTNLQDPNRFFDFFSSQPSATNMLTWVYTNLGTPASYRTMDGFGVHAYKWINRKGEVNYVKFHWKSQQGVKSLRPAEVTKVQGEDFNHLTNDLYTQINAGNFPKWDLYVKVLSPKALSKLDYNGLDATKVWLDVPEKKVGTMTLNRVPDNFFLETEQSAFAPSNIIPGIEPSEDRLLQGRLFAYADTQLYRLGANLFQLPVNSPKSPVANHNQDGPSNNSTGLGNVDSLDVNYEPSRLVNLTVDKQARAVETPLSGHVQQQAIRNPRDFFQAGVLYRSLSEQDKADLIHNLSGDLNKVNDAEVKAIMVSYFYRADKEYGTRLAKATDVNLKQVTKLASM
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LSY13_CAEEL
Sequence: MEIDDCVIDMIQVFSKINREVPEKAKKAIVEIERLDILAKKEMEVAKKHKIEFFANYEEMTAEQKTKAFTFMQKKMAKVSEYSDQKIEIASGLKVLLKDVYGKFMEEEQKFIENLNKIPKAPETPPSSSPSVRSHRKKKLSEGDDDAPSSVDEKKRGRKKKPESEKAVAAAEPPKMYCWCQLDKNDTMIECENPGCKYGWFHFTCIGMITAPAGDWYCTNECRAQGLAAVAEAPQKAPQRKGLKKKK
What is the function of this protein?
Required to initiate and then maintain lateralized gene expression in the ASE sensory neurons (PubMed:20923973).  Involved in determining cell fate in the ASE neurons (PubMed:20923973).
What are the official names of this protein?
ING family member lsy-13, Laterally symmetric protein 13.
What is the protein family that this protein belongs to?
Belongs to the ING family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y459_LAWIP
Sequence: MTLKKIIPNLQKTQNNNNNSISSPLLPHTVQEYFPVIIIVGMSGAGKSTALHVFEDLQLVTADGIPPSLVTSMIHTVQSSSLEHVQGLALGINQHRIHTMQELEHTFQEMRSQHIYFTLLYLEADMPTLIKRYAATRRPHPLEQYHIGLEHALEEEAKRLIPIRQTADIVLDTTTYSIHDLRRFLQKSWNPYPEKIRSIKINIISFGFKYGVPNEADLLFDLRFLPNPYFVEELRPLSGMDKKVATYVLNSASGIKFKKHLIRFLSFLLPLYDAEGRYRITIALGCTGGKHRSVAISELLLHELTKKNYTVSIEHRHMELG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein LI0459.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: XERC_SHEON
Sequence: MNPPADDMPARCHSYLQQFEAYMQSERQLSAHTVRNYLYELQRGRELLPEGIDLLNVGREHWQQVLAKLHRKGLSPRSLSLWLSAVKQWGEFLLRAGAIELNPAKGLSAPKQAKPLPKNIDVDSLTHLLEIDGNDPLTLRDKAIMELFYSSGLRLAELAALDLSSVQYDQREVRVLGKGNKERIVPVGRYAIDAISAWLECRRQIPCEDNALFVTEKGKRLSHRSIQARMSKWGQEQALSMRVHPHKLRHSFATHMLESSADLRAVQELLGHENLSTTQIYTSLDFQHLAKVYDNAHPRAKKQQDK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF2_CAVPO
Sequence: MRTVPLFAACLLLTLMAQAEPLPRAADHSDTKMKGDREDHVAVISFWEEESTSLQDAGAGAGRRCICTTRTCRFPYRRLGTCLFQNRVYTFCC
What is the function of this protein?
Has antibiotic, anti-fungi and antiviral activity.
What are the official names of this protein?
Neutrophil cationic peptide 2, CP-2, GNCP-2.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_CUTAK
Sequence: MNPAERPDTSLCGVRLAIDWGKARIGVAASDRDAILAFPVETVHTADRPVQRLAEIVAEYEPVEVIMGLPVALNGTEQLAAQDVRDAGRQLTEAINPIPVRWVDERMTTRTAARALHEAGRNARKQRGVIDQAAAVAILEHVLEQVRLGQSETATGGADS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_PELPD
Sequence: MLKEFKEFAIRGNVIDLAIGIIIGGAFGKIVDSLVKDVIMPPVGMIMGKMDFASLFLNLSGTEYATLAEAKKAGAATLNYGIFISTIVDFLIMAFVVFLMVKQINRMKKEAPAPVAASDSKDCPFCLSPIPLQATRCPHCTSNLK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSN_TOLAT
Sequence: MNSTIAEAIKEEGIENYLKNQQHKSLLRFLTCGSVDDGKSTLIGRLLHDSRQVYEDQLKTLHSDSQKIGTTGEKLDFALLVDGLQAEREQGITIDVAYRYFSTPKRKFIIADTPGHEQYTRNMATGASTCDLAIILIDARRGVLEQTRRHSFIASLLGIRQFIVAVNKMDLVNFDEKVFDSIKKEYLEFASGLPKTDIRVVPISALDGENLVVNSELTPWYQGEPLLTMLENAEVGTRDLDLPFRMPVQLVSRPNLDFRGYMGTVAAGVVKPGDVVKVLPSGKESKVKRIVTFDGDLDYALPGEAVTITLEDEIDISRGDLLVAPDAETQVTQHVLANVVWMTEEPLQANRQYDIKLATRKTRGHVDAIRHRIDVNTLEKHDATELKLNEIGLLELSLTNAVGVDPYNTVRDTGSFIIIDRLSNVTIGAGMVVEALAGKTAGKAEFSEFELEFNALVRKHFPHWQALDISKL
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: UDG5_ECOLX
Sequence: MFGTLKITVSGAGYVGLSNGILMAQNHEVVAFDTHQKKVDLLNDKLSPIEDKEIENYLSTKILNFRATTNKYEAYKNANYVIIATPTNYDPGSNYFDTSSVEAVIRDVTEINPNAIMVVKSTVPVGFTKTIKEHLGINNIIFSPEFLREGRALYDNLHPSRIIIGECSERAERLAVLFQEGAIKQNIPVLFTDSTEAEAIKLFSNTYLAMRVAFFNELDSYAESFGLNTRQIIDGVCLDPRIGNYYNNPSFGYGGYCLPKDTKQLLANYQSVPNKLISAIVDANRTRKDFITNVILKHRPQVVGVYRLIMKSGSDNFRDSSILGIIKRIKKKGVKVIIYEPLISGDTFFNSPLERELAIFKGKADIIITNRMSEELNDVVDKVYSRDLFKCD
What is the function of this protein?
Catalyzes the formation of UDP-glucuronic acid which is required for K5 capsule synthesis.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: SSUB_ACIAD
Sequence: MTIMSNLNIPLFPDQEKDLSSSASQPETAPIGAEILIEQLHKFYGQIKVLEDLDLHIQAGEFIAIVGRSGCGKSTLLRLIAGLEHTSYGEIKFKSARHFREGITSDDIRVMFQDPRLLPWKSILHNVQLGLNKQQLPIAEQLLEKVGLKDKAGQWPSQLSGGQRQRTALARALSHSPRILLLDEPLGALDALTRLEMQSLIERLWKEQGFTAILVTHDVSEAVQLADRIILLDKGHIAQSFEVNLPRPRHKSLEFAQLEQQVLEAVLAT
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADA_YERPS
Sequence: MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAVGSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHEIHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_SHIF8
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPAEAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC11_MOUSE
Sequence: MATALSEEELDNEDYYSLLNVRREASSEELKAAYRRLCMLYHPDKHRDPELKSQAERLFNLVHQAYEVLSDPQTRAIYDIYGKRGLEMEGWEVVERKRTPAEIREEFERLQREREERRLQQRTNPKGTISVGVDATDLFDRYDEEYEDVSGSGFPQIEINKMHISQSIEAPLTATDTAILSGSLSTQNGNGGGSVNFALRRVTSAKGWGELEFGAGDLQGPLFGLKLFRNLTPRCFVTTNCALQFSSRGIRPGLTTVLARNLDKNTVGYLQWRWGIQSAMNTSIVRDTKTCHFTVALQLGIPHSFALISYQHKFQDDDQTRVKGSLKAGFFGTIVEYGAERKISRHSVLGAAVSIGVPQGVSLKVKLNRASQTYFFPIHLTDQLLPSAVFYATVGPLVVYLAVHRLIIRPYLRAQKEKELEKQRENTASDILQKKQEAEAAVRLMQESVRRIIEAEESRMGLIIVNAWYGKFVNDKSRKNEKVKVIDVTVPLQCLVKDSKLILTEASKAGLPGFYDPCVGEEKSLRVLYQFRGVLHQVMVPDSEALRIPKQSHRIDTDG
What is the function of this protein?
Required for mitochondrial inner membrane organization.  Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex.
What are the official names of this protein?
DnaJ homolog subfamily C member 11.
What is the protein family that this protein belongs to?
Belongs to the DNAJC11 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: APT_PSEU2
Sequence: MTFDQSNFKSLIRPVVDFPKPGVVFRDITPLFQSPKATRQVIDSFVQRYIDAEFSHIGVMDARGFLIGSVVAYQLNKPLVLFRKQGKLPADVLSEAYQTEYGEAYLEVHADSLCEGDSVVMFDDLIATGGTLIAAANLIRRMGAEVYEAAAIIDLPELGGSKRLNDLKIPTFCLTEFALDEQ
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_CHLP8
Sequence: MTSRRKLILASQSPRRRELLAMTGIPFETASVEIDETFDPALTVEKNVMAISKQKAEAVMWTLPQDAGEAIVLGSDTTVVLDGAALGKPGDADHAFEMLSALQGRSHEVLTGFCILHDGKAITDYARTIVEIGAMTPGEITRYIEVMKPFDKAGSYGIQDPLLACFVTGIDGCYYNVVGLPVSKVYAALKPLFPLDANR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAT_HV197
Sequence: MEPVDPNIEPWNQPGSQPKTACNQCYCKKCCYHCQLCFLQKGLGICYGREKRRQRTTTPYASKNHKDPIPKQPLPQARGDPTGPKESKKEVESKTKTDP
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: GLCC_ECOL6
Sequence: MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRALLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQASHNQVLVFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQRAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS
What is the function of this protein?
Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity.  Also negatively regulates the transcription of its own gene.  Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector.
What are the official names of this protein?
Glc operon transcriptional activator, Glc regulatory protein, HTH-type transcriptional regulator GlcC.
Protein: STX8_MOUSE
Sequence: MAPDPWFSTYDSTCQIAQEIAEKIQERNQCERRGEKTPKLTLTIRTLLKNLKVKIDLLKDLLLRAVSTRQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAEPDLIRSSLMSEEAKRGTPNPWLCEEPEETRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRTEARRVTLVDRKSTSCGMIMVILLLLVAIVVVAVWPTN
What is the function of this protein?
Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.
What are the official names of this protein?
Syntaxin-8, Syntaxin-like protein 3I35.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein. Note=Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity).
Protein: FLP_STAAC
Sequence: MTTKKLYFLSISIIIIVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKAFTGLAILKLAQEGRLNLNDAVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDSVTSKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNYKSKHDAIGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDEHLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKDQFNIVTVLMTTLILLAFIFSAYRAWQMRHGQILLRRSKRIAVLSWLSLCICIALALILYALPYLILGSNNWSFVLTWLPIEIKLALITTLIALFSTLIVILLFLHTKITKT
What is the function of this protein?
Its precise function is unknown.  Has no penicillin-binding activity and is not involved in methicillin resistance.
What are the official names of this protein?
Protein flp, FmtA-like protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YOE1_STRAT
Sequence: IPRHPTLANVRQAFAEQPLAHAALNSLLVALATAAVTVLIATPMAYVMARHRTKAARAATGWVVVSQAFPFVLLIIPLFLVLKRLRLIDSLTGLVLVYVVWSLPFALWMLAGHARAVPAELEEAAAVDGAGRVRTLTSVTVPLLAPGIAATALFAFVTAWNEFFFALVLLKSPHRQTLPVVLTHFIGAEGVPTSPAGAAAFLATLPSLAFFALVQRRITSGLLTGAVKN
What is the function of this protein?
May participate in oleandomycin secretion during antibiotic production.
What are the official names of this protein?
Putative ABC transporter permease protein ORF1.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CARA_WIGBR
Sequence: MENILLNKALLILEDGTKFYGNSIGAKGTSIGEVIFNTSITGYQEIITDPSYFNQIVAFTYPHIGNIGIEINNNESSKIQVKAVILYQTHNIISDFRNKLSFSRFLLLNNIIGISGIDTRKLTRLIRKSGTQYGYVSSEGTNINFKEIKSKIKIFLEKKNLDLVKLVTTKRKIIYKKKYIEKNFFYNIVAYDFGIKFSIIKNLINLGCRITLVPATTKSKYVISLNPDGILLSNGPGNPEIYKYAIRNIQCLLETKIPIFGICLGHQLLAIANGAKILKMKFGHHGSNHPVKDLETNKIIITSQNHDFAIDKSTLSKNIIITHISMFDQTLQGIKLINKPVFSFQGHPESSPGPKDALFLFKNFINLVKDYRLNKK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: HIS2_PYRAR
Sequence: MSCKVLEELEEVIRRRIEEGNPESYTYRLYSSGIPHIARKVGEEAVEAAVAAIAEGRERLAEEAADLLYHLLVLLNAAGLSLRDVCNVLEKRRK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1C_NOSP7
Sequence: MNSGIDLQGTFIESLRDLGIPAGTAKAIWMPLPMILMLIGATVGVLVATWLERKISASAQQRIGPEYQGPFGLLVPVADGLKLVFKEDIVPAKSDPWLFTLGPIIVVIPVFLSFLIVPFGQNIVISNVGMGVFLWIALSSIQPIGLLMAGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAIAMMSNSLSTVDIVNQQSGYGILGWNIWRQPIGFLIFWIAALAECERLPFDLPEAEEEIVAGYQTEYSGMKFGLFYLGSYVNLILSSLLVAILYLGGWDFPIPLNLIAGWLGVSELNPVFQIITASLGITMTVFKAYLLVFVAILLRWTVPRVRIDQLLDLGWKFLLPVGLVNLLLTAALKLAFPFAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SYT_METM6
Sequence: MKTLLIHSDYLEFEAKEKTKIAEDADVLSGKMDECLTVFIAVEKDDESDPDAVVKNAVEEIVKTADNLKVKNVVVYPYAHLSSDLGSPATAKEILAEIEKELSGNYEVLRAPFGWYKAFKISCKGHPLSELSRKITTERKEEVKKEKVVSKFYIINGENLELTEVNDEVISKMEDKGLLALLKHELDIKEEGKENGEPPHVKYIKEKEICDYEPSSDAGHFRWYPKGKLIRDLLSDYVYNLVVERGGMPVETPVMYDLQNNAIREHADKFGERQYRFKQGNKDLMLRFAACFGQFMMKKDMYLLPKHMPLKLYELSTYSFRYEQRGELVGLKRLRAFTMPDMHTVCIDMKQAMEAFEDQLWMGLKTGDDFKTPYAIIFRFTEDFFEENKEWFFGMAKEYKQKYGKDAILEILPGRKHYWVGKVDMAVVDSFGRPIENPTVQIDVESAERFGIVVHDGDKKVHPIILHCSPTGSVERVLCGLLENAYLNTLENRPPALPTWLTPVQARVIPVGDKHSAFALDVATKLRASGIRADFDDREDSMGKKVRNAGTDWVNYVVVIGDSEMESGKLTVTVREESELKKAKKEELTVEELIEKITSDVKDAPKRPLPLPMKCSVQPIFR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.