PharMolix/UniProtQA huggingface dataset:
Protein: DGCR8_BOVIN
Sequence: METCGSPSPLPREPAGGVAMEDRARPLRALPRGQSPPPPLQTSSDAEVMDVGSGGDGQAEPPAEDPLNFYGASLLSKGSSSKARLLVDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSEDRKVLYTGAERDVRAECGLALSPVIGDVHAGPFGGSVGNGVGAGGESAGKRDEEHELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFSYEDDFDNDVDALLEEGLCAPKKRRMEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHGPPLTSIPCLHYRKMKDSEERERAAGIAPPEPELPPDEPDPLGTDAGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRNYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYSFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPRDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQFARKNKPNLHILSKLQEEMRRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
What is the function of this protein?
Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis.  Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus.  Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.  The heme-bound DGCR8 dimer binds pri-miRNAs as a cooperative trimer (of dimers) and is active in triggering pri-miRNA cleavage, whereas the heme-free DGCR8 monomer binds pri-miRNAs as a dimer and is much less active.  Both double-stranded and single-stranded regions of a pri-miRNA are required for its binding.  Specifically recognizes and binds N6-methyladenosine (m6A)-containing pri-miRNAs, a modification required for pri-miRNAs processing (By similarity).  Involved in the silencing of embryonic stem cell self-renewal (By similarity).
What are the official names of this protein?
Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8 homolog.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies.
Protein: SYV_STRP6
Sequence: MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVVHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVLLPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTERQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDFIRAVRNARAEVNVAPSKPITILVKTADSELEDFFNSNINYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIVEMHKLVK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_SHESW
Sequence: MKFSPLLDELIQSLRCLPGVGPKSAQRMAFQLLERDRKAGLKLASALSSAMSDVGHCQSCRTYTEETLCPICASHKRGSSSTICVVETPADVLAIEAGGHFTGRYFVLLGHLSPLDGVGPEELGLALLERHLASGDVSELILATNPTVEGEATAHFIADMARRHKVMISRIAHGVPVGGELEYVDSTTLALSFNGRLPL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: VDLD_HELPJ
Sequence: MPQIQSSHSNHFDFTIDTADRTKLLMSYLVVPTTANFNNVMHGGELLNLLDKVAYVCSTRYCAKGTVTLSVDGVTFKYPIPVGNLLTFLASINYVGNTSCEVGIKVLSEDIKTREITHTNSCYFTMVAVENGKPTPMPKYEPKTEVEIRRYEGALKRKEMRTRGYLKSGKHEGV
What are the official names of this protein?
Protein VdlD.
What is the protein family that this protein belongs to?
Belongs to the acyl coenzyme A hydrolase family.
Protein: QSOX2_ARATH
Sequence: MSLVHLLLFAGLVIAASSSSPGSRLILREISDQKDKAVELNTTNFDSVLKDTPAKYAVVEFFAHWCPACRNYKPHYEKVARLFNGPDAIHPGIVLMTRVDCAMKTNTKLCDKFSVSHYPMLFWGPPTKFVSGSWEPKKDKSEILVIDDGRTAERLLNWINKQIGSSYGLDDQKFKNEHALSNLTDYNQISQAVYDVEEATAEAFDIILAHKAIKSSETSASFIRFIQLLAAHHLSRRCRKGAAEILVNYDDLCPSGNCSYEKSGGNDTLGNFPICGKDVPRGYYMFCRGSKNDTRGFSCGLWVLMHSLSVRIEDGESHFAFTTICDFVNNFFMCDECRLHFNDMCLSVKTPFKKARDFVLWVWSTHNKVNERLLKDEASLGTGDPKFPKIIWPPKELCPLCYLSSNQKSIEWDHEHVYKFLKNYYGPKLVSLYKEKSVSRSKEETVSATEDLTVATNALVVPIGAALAIAIASCAFGALACYWRTQQKNRKPRRR
What is the function of this protein?
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.  May contribute to disulfide bond formation in a variety of secreted proteins (By similarity).
What are the official names of this protein?
Sulfhydryl oxidase 2, Quiescin-sulfhydryl oxidase 2, AtQSOX2.
What are the subcellular locations of this protein?
Secreted.
Protein: URED_SYNR3
Sequence: MTDTPNQLPPWRGSVSLDFELAADGTTQWQGGARSPLKLLRHFTAGDGRCVMPLLHTAGGLVGGDQLEIALHAAAGSRSFLTSVAAQKIYGSRGRSRVQPQGRWAQITLQAELEAGADLEWLPQETVVFAGALLEQQQQITVAPGASWLGADVVRLGRTARGEDLGAGRFCNSLSIRRGEQWSVVERLSLEQEQLPNPHGMGGEPVLGTLIWIAPEPLENEQLAQLLKGGRADREGLSGTMAIGPLEPGLIARYRGGSSQAARLWFFRLWRRIRAVQGLSEPSWPRTWPFQEAELALNPEPATTATTAAR
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_SHEB8
Sequence: MDDNKRPLYLPFAGPAILEAPLINKGSAFSEEERIFFNLEGLVPYAIETIEEQASRAYDQFRSFNNDLDKHIYLRNIQDTNETLFYRLVQNNISEMMPIIYTPTVGLACERFSKNYRRNRGLFISYPNKDRIDDILNNSTRQKVKIIVVTDGERILGLGDQGIGGMGIPIGKLSLYTSCGGISPAYTLPITLDVGTDNPQLLEDPMYMGWRHPRIGGEEYAEFIEAFMQAVHVRWPDTLIQFEDFAQKNAMPILERYKDRYCCFNDDIQGTAAVAVGSLLAACKAAGTELNQQRIAFLGAGSAGCGIAEAIVAQMVSEGISDEQARTQVCMVDRWGLLLDNMPNLLPFQQKLAQKCTNIQNWSNFSDNISLLDVVNNTKPTVLIGVSGVPGLFTEEIIRAMHSHCARPIIFPLSNPTSRVEATPKDILHWTSGQALVATGSPFEPVVVDGETFEIAQCNNSFIFPGIGLGVLASGARHVSDAMLMASSRALAECSPLAIDGSGPLLPKLEDIHAVSKHIAFAVGKVAVEQGLTLPMSDEILQQSIEGNFWSPEYRRYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: EFG_LATSS
Sequence: MANKREFPLDKTRNIGIMAHIDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAEWKGNRVNIIDTPGHVDFTIEVERSLRVLDGAITVLDAQSGVEPQTENVWRQATTYGVPRIVFVNKMDKLGANFDYSMTTLEDRLQANAHAVQMPIGAEDEFQGVIDLIEMQADIYDEDELGAKWDTVDVPADYLEEATKRRAELVEAVADVNDDIMDKYLEGEEISKEELKAAIRQATIDLKFFPVFAGSAFKNKGVQMLMDGVVDYLPSPLDVRPYNAKNPEDDSEVELMAGDDKPFAGLAFKIATDPFVGRLTFFRVYTGTLQSGSYILNATKDKRERVGRLLQMHSNHRNEIPEVFSGDIAAAIGLKNTTTGDSLTDVDHPLILESMEFPDPVIQVSVEPESKEDRDKLDLALQKLAEEDPTFKAETNNETGETLISGMGELHLDIMVDRMRREFKVVAKIGEPQVAYRETFTKQASAQGKFVRQSGGKGQYGDVWVEFTPNEEGKGFEFEDAIVGGVVPREYIPSVEQGLKESMANGVLAGYPLIDVKAKLYDGSYHDVDSNESAFKIAASMALKNAAKQAGAEILEPIMKVEVIAPEEYLGDIMGQVTARRGAVEGMEARGNAQIVNAMVPLSEMFGYATTLRSATQGRGTFTMVFDHYSAVPKSIQEEIIKKNGGQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_CERDE
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKLK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PPID_CRYNJ
Sequence: MSNTIAYFDITIANEPAGRLTFELFDDVVPKTANNFKHLCIGDKTNEAGVKLAYAGSSFHRCIKGFMLQGGDFTRGDGTGGESIYGEKFEDENFELKHDKPMLLSMANAGPGTNGSQFFITTVPTPHLDGKHVVFGRVIYNRSLVRRIENIPTTSDRPDQAVTISSAGVLSPDEFAQLEAERQAKQAGSDGGDIWEDWPQDEEGVDAEKPEEALVVAGKLKEVGTKEFKAGNFAVALDKYQKALRYLDVHPVLPNDSPAELVESFRSLRLPLLTNAALCALKLPASPNTSSLVVSLTSRALTLPNLSASEKGKALYRRAQAYVLKKDDEAAEKDLKGALECVPGDAGVIKLLKDVEAKRKARREKERQAFAKMFG
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_OUMVV
Sequence: MGDNALDLATASSTPIPMPNTGQLVISPQDIGYSDPPKLRGRLKLEFVHDISLDANVEDPIALIPHGIWSIFKSKLAQMRCPKGYITYDKVILSWKPHVATGLARGQIAVVDTRVNHTSIEDLMHKALWKTAPVDLGCTYTIQGTVPYCLPFHPKEGGDVKSDLESQNPIRGIVYITDSRYQEAARHGALTMTLKLSIGTMPTDALTGPRATLSQPHLRDNLRSRSQRISRPPIGITQRPRRSLAEPPLEKEEEQESTLSSEASGSEQGLIIPVQGPSTSSRSRRVRG
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (Potential).
What are the official names of this protein?
Putative movement protein, Cell-to-cell transport protein.
Protein: RRF_LIMRD
Sequence: MATGKEILNDAKQKMAKSGYALQRTLADIRAGQANASLLNSVKVEYYGAPTPLNQVASITIPEARQLLITPYDESVLEEIEKAIYASNLGLTPQNDGSSIRLIIPQLTEDRRKELVKDVKAELEKAKVAVRNVRREAMDDLKKGNKNGDFNDDEFHDLEKKVQNETDAGIKNLEDIANAKEKELMEG
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_ACIC5
Sequence: MAEVRLQEGEPLENALRRFKRKVQQEDIIKEVKRHSFYLKPGEKRRVKEALARKRNRKKARKEQD
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RNA14_KLULA
Sequence: MSDGTATPDPLPSSSNTSTSLRPTSRVRDESDVIGKLNDMIEEQPTDIFLYVKLLKHHVSLKQWKQVYETFDKLHDRFPLMANIWCMRLSLEFDKMEELDAAVIEPVLARCLSKELGNNDLSLWLSYITYVRKKNDIITGGEEARNIVIQAFQVVVDKCAIFEPKSIQFWNEYLHFLEHWKPVNKFEEQQRVQYIRKLYKTLLCQPMDCLESMWQRYTQWEQDVNQLTARRHIGELSAQYMNARSLYQDWLNITKGLKRNLPITLNQATESNLPKPNEYDVQQLLIWLEWIRWESDNKLELSDDLHKARMTYVYMQAAQHVCFAPEIWFNMANYQGEKNTDSTVITKYLKLGQQCIPNSAVLAFSLSEQYELNTKIPEIETTILSCIDRIHLDLAALMEDDPTNESAINQLKSKLTYVYCVYMNTMKRIQGLAASRKIFGKCRRLKKLVTPDIYLENAYIEYHISKDTKTACKVLELGLKYFATDGEYINKYLDFLIYVNEESQVKSLFESSIDKISDSHLLKMIFQKVIFFESKVGSLNSVRTLEKRFFEKFPEVNKLEEFTNKYKVLDVNYLQRLELDYMVRDVMPEAIALDRGSNNLKRTMREEEDGQAFKKFKANEDPIPPEIVELLKVLPKRQYFKVTIFEAHAFSEFLSDKVTIQ
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA 3'-end-processing protein RNA14.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Protein: FLIW_GEOMG
Sequence: MKIETSRFGLLDIDDDKIITLPDAMPGFAETRFTLLNPEKHAPFCWLQSVDNPDLAFVMVDARQTLPDYAVSLTSDEYERLSLDEKSNTVVFLVVTLATDPADITVNLQGPIVLNPERMIAKQIVLEGSRFPSRHPLFGIAKGRETVETSCAG
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_CDVO
Sequence: MTEVYDFDQSSWYTKGSLAPILPTTYPDGRLIPQVRVIDPGLGDRKDECFMYIFLMGIIEDNDGLGPPIGRTFGSLPLGVGRTTARPEELLKEATLLDIMVRRTAGVKEQLVFYNNTPLHILTPWKKVLTSGSVFSANQVCNTVNLIPLDIAQRFRVVYMSITRLSDDGSYRIPRGVFEFRSRNALAFNILVTIRVEGDVDSSRGNLGMFKDYQATFMVHIGNFSRKKNQAYSADYCKLKIEKMGLVFALGGIGGTSLHIRCTGKMSKALNAQLGFKKILCYPLMEINEDLNRFLWRSECKIVRIQAVLQPSVPQDFRVYNDVIISDDQGLFKIL
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: LGT_FINM2
Sequence: MDRVAFSIFGIDIMWYGILITLGVILGYVVAVKLAKMENISENTILDILVWALPLAIVGARAYYVIFEWDYYSKNLGEIIDIRGGGLAIYGGIIAAVITCYVICKKKNLKFLKMLDIFMPAIALGQAIGRWGNFINKEAYGTPTNLPWAITIDGVKVHPTFLYESLGDFLIFLLLVYVFKNRKKFNGQITSMYMILYGILRFFVEGLRTDSLYIGALRVSQLVSIAIIIAGVILQIKYKKQIIKSDEK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: X_BPPHM
Sequence: MLKFLNLTSTSLVLTSAYNVQNIYLAELLISNRIQFHKRLHQQRTAHKVTSPPSQRPQNSETKSDSQNRS
What are the official names of this protein?
Uncharacterized protein X.
Protein: LPXC_BRUC2
Sequence: MNAYQKTIGRAVTLSGVGVHGGAPASARLLPADADTGILFQRSDIKDSAPVCAHVSQIGATDLCTSLGAREARIDTVEHLMAAISALGIDNLVVEIEGPEVPILDGTSARFIEAVDSVGVVTQDAKRRFIRILKTVRVEAGNSWGEFRPYDGTRFEVEIDFECPLIGRQKFAHDVDEETFRKELSTARTFGFMKDVERLWAAGLALGASLDNSLVIGDDNSIVNADGLRFKDEFVRHKTLDAVGDLALAGLPFIGCFSSYRGGHRLNSEAVKALLSDETAFEIIEA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: YR566_MIMIV
Sequence: MYSFILDCTTRTAKKVKMHVIDIYNKYHELLVFCRQQLIQKNFEMSKSNAVELYSKRQDEIHDEYQKRKRREIKVIKSDLIELRRQKDEVIENMKTFKHDVVKYKKLYEDLEQEIKILERKNKNLEIETNSDSGNLMVYIANIENILSKCTNKSLKRNIEKQLYKMDEIAYKLKDNFREEFE
What are the official names of this protein?
Uncharacterized protein R566.
Protein: HRI1_YEASL
Sequence: MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKVNDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNBEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIPQSYENLKKGSTVTSNGLNWEVIEYHA
What are the official names of this protein?
Protein HRI1, HRR25-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the HRI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ECP1_MOUSE
Sequence: MGPKLLESRLCLLLLLGLVLMLASCLGQTPSQKFAIQHINNNTNLQCNVEMMRINRARRTCKGLNTFLHTSFANAVGVCGNPSGLCSDKRSQNCHNSSSRVHITVCNITSRATNYTQCRYQSRRSLEYYTVACDPRTPQDSPMYPVVPVHLDGTF
What is the function of this protein?
Cytotoxin and helminthotoxin with ribonuclease activity.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Eosinophil cationic protein 1, ECP 1, Eosinophil secondary granule ribonuclease 1, EAR-1, Ribonuclease 3-1, RNase 3-1.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: NUOB_ERYLH
Sequence: MTADHNRALHDAPTARGGEVRQPDGDYFNALQTEVNDKGFLVTSTEDLFQWARTGSLWWMTFGLACCAVEMIHVNMPRYDMERFGAAPRASPRQSDVMIVAGTLCNKMAPALRKVYDQMSDPKYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGVMQLQRKIRRSGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRR_STRPS
Sequence: MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: UBIA_NEIMF
Sequence: MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIPMAFAAVGNSVPVEAWILFTANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGAAWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEOC_CHRVO
Sequence: MSALIEAARRALSLMDLTTLNDDDTDEKVAALCRKAKSPDGTVAAVCVFPRFVPIAKKTLREAGCPEVQVATVTNFPHGNDDVSIAVAETRAAIAYGADEVDVVFPYRALMAGNRDIGFELVKACKEACGGKLLKVIIESGELKDAALIREASEISIRAGADFIKTSTGKVPVNATLPAAETMLAVIKEQGGQCGFKAAGGVKSATEAAEYLALAARLLGEDWVSARHFRFGASSLLANLQIEIAGGVAKPSSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_ECOHS
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: PHK_RHOPA
Sequence: MSDVLSNDLLQKMDAYWRAANYLSVGQIYLQDNPLLDQKLQLDHIKPRLLGHWGTTPGLNLLYVHLNRLITEHDLDMIYITGPGHGGPGLVANAYLEGTYTERYPAIERSRNGMQRLFRQFSWPHGVPSHVSPETPGSIHEGGELGYSLAHAYGAAFDNPNLIVACVVGDGEAETGALATSWHSNKFLNPARDGAVLPILHLNGFKIANPTVLARITPQELTDLMRGYGYEPHFVEGDDPAVVHQTLAATLERVLGEIRAIQDKARNHGDTERPRWPMIVMRTPKGWTGPKQVDGKPVEGTWRAHQVPIADFKNPEHLTLLEDWMRSYRPDELFDATGKLRDELQALAPTGRRRMSANPHANGGELLEPLSLPDFHDYAVTLTGPGALKAEATRVLGTFLRDVMKNSLESENFRLFGPDETASNRLDAVLQVSPKEWMAAIEDVDVDLSPDGRVMEVLSEHLCQGWLEGYLLTGRHGFFSCYEAFIHIIDSMFNQHAKWLKACATIPWRKPIASLNYLLTSHVWRQDHNGFSHQDPGFIDHVANKKSNVVRIYLPPDANCLLSVADHCLRSRNYVNLIVAGKQPEWQWLDIDAAVRHCTTGAGIWHWASDEGEPDVVMACAGDVPTVETLAAVKLLREYVPDIKIRVVNVVDLMVLQPSSEHPHGLDDRRFDELFTTDKPVIFAFHGYPWLIHRLTYRRRNHVNIHVRGYKEEGTTTTPFDMVVLNDLDRYRLALDAILRIPRLADQRDAATSRYWATMQRHKLYIGEHGDDLPEVRDWRWSA
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.