PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_CUPMC
Sequence: MRILGIDPGLRTTGFGVLEKHGNKLAYVASGTIRSNGETSLPERLKTLYDGISEVARTYAPDCAAIEKVFVNVNPQSTLLLGQARGAAICGLVGQGLPVFEYTALQLKVAVVGYGRANKEQVQEMVMRLLSLSGRPSSDAADALGVAICHANGGDTLGTLAGLAPELARKGMRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MURG_NOSS1
Sequence: MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVEGFQQGLGISSLVILGKLIGSILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVATKYLPRATSVCVGTPVRSQFLNLGNNSQLDLAIPGDVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIELPFYDNMAALLQRANLAISRSGAGSLTELTVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALTFKQSDLTAELLQTQVLNLLQSPTELAKMGENAKAIAVPDSADKLATLVREVVER
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYE_BURPS
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDLERSTEASVDAILEGMAWLGLDYDEGPYYQMQRMDRYREVLAQMLEKDLVYPCYMSTEELDALRERQRAAGEKPRYDGTWRPEPGKVLPEPPAGVTPVLRFRNPLTGSVVWDDAVKGRVEISNEELDDLVIARPDGTPTYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQGEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHNKLNWLNNHYIKEADDARLAELAKPFFAALGIDADTIARGPDLVGVMGLMKDRASTVKEIAENSTMFYRAPAPDAQALAQHVTDAVRPALAEFAAALKTAEWTKEAIAAALKAVLGAHKLKMPQLAMPVRLLVAGTTHTPSIDAVLLLFGRDVVVSRLAAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBCD_BORBU
Sequence: MSNYKILHTSDWHIGKKIENFSILKEQKNFLYFLLEFIKKENIDLLLVAGDVYDSKRPGFEEQRLVNNFFYELSFTSCKWCVVISGNHDKKDYLSINKKLLSRFNFFLITEYDSDEQIVLLKDNGNLKFIVVCLPHINERLILGQNFDNIFGLEDQYSSKLFLENLENAYREKISNLSNFLENKYKGIPKILMAHSFFGSSKKIDTLGGSYIIPFNVFGNGFSYVALGHIHKFMKLRDNIVYSGSPMQYSFNETCDKYINVLHFNDNKLILQEAFPVPIFNKLIFAKGSLNEVLDFLANSKKEESFTIYLKIELNEAVDTSAEESIYDLARLNFMNLVSISYSLPSSQDLQDDSNFIGELEVLEMDEKYFFEKKLRWDFENGVIRDIKFKEEELISLFNEVLANGYLGEYEDK
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: NAPA_RHIME
Sequence: MTGELTRREMLKAHAAGIAAATAGIALPAAAQPVPGGVEALQITWSKAPCRFCGTGCGVMVGVKEGQVVATHGDMQAEVNRGLNCIKGYFLSKIMYGTDRLKTPLLRKRNGAFAKDGEFEPVSWDEAFDVMAEQAKKVLKDKGPTAVGMFGSGQWTIFEGYAATKLMRAGFRSNNLDPNARHCMASAAYAFMRTFGMDEPMGCYDDFEHADAFVLWGSNMAEMHPILWTRLADRRLGHEHVKVAVLSTFTHRSMDLADIPIVFKPGTDLAILNYIANHIIQTGRVNEDFVRKHTTFMVGATDIGYGLRPDNPLEVKAVNAKDAAKMTPSDFESFKSFVSEYTLDKVVELTGVEAGFLEQLADLYADPKRKVMSLWTMGFNQHVRGVWVNQMVYNLHLLTGKISEPGNSPFSLTGQPSACGTAREVGTFAHRLPADMTVTNPEHRKHAEEIWRIPHGIIPEKPGYHAVEQDRMLKDGKLNFYWVQVNNNVQAAPNTQNETYQGYRNPDNFIVVSDVYPTITAMSADLILPAAMWVEKEGAYGNAERRTHVWHQLVDAPGEARSDLWQMVEFSKRFTTDEVWSTDILDANPGYRGKTLYDVLFKNGNVDSFPASEINKEYANREAEAFGFYIQKGLFEEYASFGRGHGHDLAPYDRYHDERGLRWPVVDGKETLWRYREGYDPYVKPGEGVKFYGRPDGKAVILAVPYEPPAESPDDEYNVWLVTGRVLEHWHSGSMTMRVPELYKAFPGAVCFMNAGDARDRGINQGAEVRIVSRRGEIRARVETRGRNRMPPGVIFVPWFDASRLINKVTLDATDPISKQTDFKKCAVKIVSVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: OTC_THEP1
Sequence: MSVNMKGRSLLTLLDFSSEEIRYLLDISKQVKMESRSRLRTERFKGMTLAMIFEKRSTRTRLAFETAFAEEGGHAIFLSPNDIHLGTKESLEDTARVLGRMVDAIMFRGYKQETVEKLAEYSGVPVYNGLTDDFHPTQALADLMTIEENFGRLKGVKVVFMGDTRNNVATSLMIACAKMGMNFVACGPEELKPRPDIFERCQEIARETSASVSFTSNLEEALAGADVVYTDVWASMGEEDKEKERISLLKPYQVNKRVMEMTGKPETIFMHCLPAVKGQEVTYEVIEGKQSRVWDEAENRKHTIKAVMIATLL
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_DELAS
Sequence: MTDQEFLDLAERLLLAVEQDCDRINDETDADLDAQRVGGMVTLVFANRSQIVINQQKPLHEIWLAAKAGGFHYRYDAAQGAWLDTKGAGEFFANLSRYATEQSGLALQFSAR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: B3GL1_PIG
Sequence: MAPALPITLPSKMSLRSLKWSLLLLSLLSFLVMWYLSLPHYNVIERVNWMYFYEYEPIYRQDFHFTLREHSNCSHQNPFLVILVTSHPADVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKVLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNARYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSGLGYIMSRDLVPRIYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
What is the function of this protein?
Transfers N-acetylgalactosamine onto globotriaosylceramide.  Plays a critical role in preimplantation stage embryonic development.
What are the official names of this protein?
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1, Beta-1,3-GalNAc-T1, Beta-1,3-galactosyltransferase 3, Beta-1,3-GalTase 3, Beta3Gal-T3, Beta3GalT3, b3Gal-T3, Beta-3-Gx-T3, Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, Globoside synthase, UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RAEP_YEAST
Sequence: MLSPERRPSMAERRPSFFSFTQNPSPLVVPHLAGIEDPLPATTPDKVDVLIAGTGMVESVLAAALAWQGSNVLHIDKNDYYGDTSATLTVDQIKRWVNEVNEGSVSCYKNAKLYVSTLIGSGKYSSRDFGIDLSPKILFAKSDLLSILIKSRVHQYLEFQSLSNFHTYENDCFEKLTNTKQEIFTDQNLPLMTKRNLMKFIKFVLNWEAQTEIWQPYAERTMSDFLGEKFKLEKPQVFELIFSIGLCYDLNVKVPEALQRIRRYLTSFDVYGPFPALCSKYGGPGELSQGFCRSAAVGGATYKLNEKLVSFNPTTKVATFQDGSKVEVSEKVIISPTQAPKDSKHVPQQQYQVHRLTCIVENPCTEWFNEGESAAMVVFPPGSLKSGNKEVVQAFILGAGSEICPEGTIVWYLSTTEQGPRAEMDIDAALEAMEMALLRESSSGLENDEEIVQLTGNGHTIVNSVKLGQSFKEYVPRERLQFLFKLYYTQYTSTPPFGVVNSSFFDVNQDLEKKYIPGASDNGVIYTTMPSAEISYDEVVTAAKVLYEKIVGSDDDFFDLDFEDEDEIQASGVANAEQFENAIDDDDDVNMEGSGEFVGEMEI
What is the function of this protein?
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex.  Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B.  The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
What are the official names of this protein?
Rab proteins geranylgeranyltransferase component A, Rab escort protein, REP.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
Protein: KDPA_ECO57
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLAWLINDIPLPGTTGVERVLFSALGVSNHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALVIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMG_CLOPE
Sequence: MRYNAGSYDIVVIGAGHAGCEAGLAAARMGCKTLVCTLTLDSVAMMPCNPNIGGTAKGHLVREIDALGGEMGVNIDHTFIQSKMLNTSKGPAVHSLRAQADKKKYQERMKKVLETQENLHLRQLEVVSVEVEDGKVKGVLTKNGAFFECKAVIMTSGTYLQSRIIIGDVSYSQGPNGLSNANELSKSLIDLGIDLRRFKTGTPARINKRSVDFSKMIEQPGDEEIIPFSFISGNIDRDQVSCWLTYTNEETHKVIQENIHRSPMYNGSIKGVGPRYCPSIEDKVMRFQDKDRHQIFIEPEGDDTEEMYVGGMSSSLPEDVQVQMIKTVPGLENAEIMRTAYAIEYDCIDPTQLKASLEFKNIDGFFSAGQINGSSGYEEAGAQGIVAGINAALKVQGKDPMILTRSDGYVGVLIDDLITKGTNEPYRMMTSRAEYRLLLRQDNADFRLTEIGHNVGLVTEERWNKFKERKQNLERELERLKELQITNKTENNEKIVELGSTELKKPIRMYELIKRPELDYFSLACLDPERPDLPKDIGDQINIIARYEGYIQTQLEQVAQFKKFEKKVLPEDLDYNDVNSLRIEAIQKLNKIRPLNIGQASRISGVSPADISVLLIFLEHYRKTGKNTDN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBXN4_CAEEL
Sequence: MQWFGGNVATAIQISRKNKALLIVYITTDSEDGQIFDGFWQHIDSSNLLCAVVGIKLKAGETSAQQFADIYPTPILPAAYLIDQNGKPLEVITPLVGKTYDQFRAKFDKATAQFVNGMPTAAANQLSTPSPSPAPVQVPASTDAPIPAPTPVTAPIQSSSTSQEMTRELAEKVARAKALLEQKKQKDAEKKREADKHVKEEMTKAREAKQERDAEALVKAAKQRKMEKLAAESDKKRILAQIKADREAAQKKFGKLVNTENASENTEKKQETTVGKAVPSDRCRLQVRLPDGSTFVEEFPSNDVLNSLVEIIRQKPSIAGTTFEIQQPYPRRIFTNDDYSKTFLENQLTPSTALVVIQKSSGSSSNYGSFSLSTQTVSFVTWVLYPLTAFWNIFCGMIGWNSTGKQQDSKSKKNDGPSTSGQSGSQPQRRGMPRSAEVRRRGNVAGLENPNEDDPEERASFNGNSTQFM
What is the function of this protein?
Probably acts as an adapter for ATPase cdc-48. 1 and/or cdc-48. 2, conferring substrate specificity.  May play a role in the ER-associated protein degradation pathway (ERAD) possibly acting as a platform to recruit both ubql-1 and cdc-48. 1 and/or cdc-48. 2 to the ER during ERAD.
What are the official names of this protein?
UBX domain-containing protein 4, Erasin.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Both the N- and the C-terminus face the cytosol.
Protein: RNH_ECODH
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PK21A_CORGL
Sequence: MRKKKDGQNLPDFRKNPPKLDKKAYEKELKRLQAELVDLQQWVVETGARVVIVMEGRDAAGKGSAIKRITQYLNPRSARIEALPTPNSREKGQWYFQRYIEKLPTAGEIVIFDRSWYNRAGVERVMGFCTSQEYRRFLHQAPIFERLLVEDGIHLRKYWFSVSDEEQIERFEDRLSDPLRRWKLSPMDLQSITRWEDYSRAKDEMFIHTDIPSAPWYTVESEDKKRSRINVISHLLSTIPYEKIDRPLPEIPHRPDSESDYVRPPRDEFRYVPDVAAHLEEERIKKEEKAKKAKKPAKAAGKNSDKQKSSGGKGKKKSKK
What are the official names of this protein?
Putative GDP-polyphosphate phosphotransferase PKK2A.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
Protein: KATG_DESHY
Sequence: MEEKKCPVTGHTQHTPTGGGTKNKDWWPNQLNLNILHQNSALGNPMDPDFNYAEEFKKLDLAAVKKDLYALMTDSQDWWPADYGHYGPLFIRMAWHSAGTYRLNDGRGGAGDGTQRFAPLNSWPDNVNLDKARRLLWPIKQKYGKKISWADLMVLAGNCALESMGFKTFGFAGGREDVWEPQEDIYWGSEGEWLGDQRYSGDRDLENPLAAVQMGLIYVNPEGPNGQPSVLASGRDVRDTFKRMAMNDEETVALVAGGHTFGKCHGAGPASHVGPEPEAAPLEEQGLGWKSTFRSGKGGDTIGSGIEGAWKPNPTTWDMGYLETLFKYDWDLVKSPAGAWQWVPTDPAAADTVQDAHDPAKRHAPMMTTADLSLRMDPIFGPIAKRFRDNPEEFADAFARAWFKLTHRDMGPRSRYLGPEVPEEELIWQDPVPPVDHELIDEQDIADLKAKLLASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEINQPAQLAEVLAALEGIQTEFNSSQSGTKKVSLADLIVLGGAAAIEQAARNAGHTLVLPFTPGRTDATQEQTEIYSFAVMEPKADGFRNYLKGKSSAPAEEMLVDRAQLLTLTAPEMTVLLGGLRVLNANYGQSKHGVFTQRPETLTNDFFVNLLDMGTEWKAVSEEKALYEGRDRATGELKWTGTRVDLVFGSNSQLRALAEVYACSDSQDKFLQDFVSAWNKVMNADRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: IF2B3_DANRE
Sequence: MNKLYIGNVSEQASALDLESIFEQWKIPFSAPFLVKSGYAFVDCPDEKVAMRAIDTLSGKVELHGKVLEVEHSVPKRQRSCKLQIRNIPPHMQWEVLDGLLAQYGTVESCEQVNTDTETAVVNVRYGAKDQAREAMDKLNGFLMENYALKVSYIPDETAAADAPAVGGRRGFNPRGPPRQGSPSLGARPKLQSDVPLRLLVPTQFVGAIIGKEGATIRNITKQTHSKIDIHRKENAGAAEKPITVHSTPEGCSSACRNIMEIMQKEAIDTKITEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQDLTLYNPERTITVKGTLDACAKAEEEIMKKVRESYENDVAAMHLQSNLIPGLNLNALGLFPGAASGGISPSVVSGPPPGAQAGYQSFGAQMESETVHLFIPALAVGAIIGKQGQHIKQLSRFAGASIKIAPADGIDAKQRMVIISGPPEAQFKAQGRIFGKLKEENFFGPKEEVKLEAHIKVPSFAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTPDENDQVVVKITGHFYASQLAQRKIQEIISQVRRQQQPKPSAAGPPVARRK
What is the function of this protein?
RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs).  This transcript 'caging' into mRNPs allows mRNA transport and transient storage.  It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity).  Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (By similarity).  Involved in neuronal crest migration (PubMed:14522877).
What are the official names of this protein?
Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IMP-3, Decapentaplegic and Vg-related 1 RNA-binding protein, IGF-II mRNA-binding protein 3, VICKZ family member 3, Vg1 RNA-binding protein, Vg1-RBP.
What is the protein family that this protein belongs to?
Belongs to the RRM IMP/VICKZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Cytoplasm, Stress granule. Note=Accumulates along the vegetal cortex as oogenesis progresses. Colocalizes to extended processes in migrating neuronal crest cells.
Protein: Y1378_CORDI
Sequence: MSGHSKWATTKHKKAANDAKRGKEFAKLIKNIEVAARTGGGDPSANPTLDDMIKKAKKASVPNDNIERARKRGSGEEAGGADWQTIMYEGYGPNGVAVLIECLTDNRNRAASEVRTAMSKNGGNMAENGAVSYMFKRRGFVLVNKGELTEDDVLMAVLDAGAEEVSDAGDKFEILSAPGDVAAIRDALAEAEIEVEDSDSDFRADVLVPLEANDARKIFRLIDALEESDDVQNVYTNMDLSDEVLAELEA
What are the official names of this protein?
Probable transcriptional regulatory protein DIP1378.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZSC4D_MOUSE
Sequence: MASQQAPAKDLQTNNLEFTPSHSSGVQWVEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLIGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQYPEHEEGNVVFQFPLDARRASQGNSSHHVDFRSAPTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYRSDNIPRKKTDSLSINKRIYHSEPEEGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPRELPGLESRQEEPISDPVFLGKDHEANLPCESHQKRFRRDAKLFKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD
What is the function of this protein?
Transcription factor required to regulate early development.  Binds telomeres and plays a key role in genomic stability by regulating telomere elongation.  Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation (By similarity).
What are the official names of this protein?
Zinc finger and SCAN domain containing protein 4D.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: EF1A2_CANAL
Sequence: MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSVKWDKNRFEEIIKETSNFVKKVGYNPKTVPFVPISGWNGDNMIEPSTNCPWYKGWEKETKSGKVTGKTLLEAIDAIEPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMVVTFAPAGVTTEVKSVEMHHEQLAEGVPGDNVGFNVKNVSVKEIRRGNVCGDSKNDPPKGCDSFNAQVIVLNHPGQISAGYSPVLDCHTAHIACKFDTLVEKIDRRTGKKLEENPKFVKSGDAAIVKMVPTKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVEKSDKAGKVTKAAQKAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 2, EF-1-alpha 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABP5_BOVIN
Sequence: MATVQQLVGRWRLVESKGFDEYMKEVGVGMALRKVGAMAKPDCIITSDGKNLSIKTESTLKTTQFSCKLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLEDGKLVVVCVMNNVTCTRVYEKVE
What is the function of this protein?
Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind.  In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (By similarity).  Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival.  May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling.  Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity).
What are the official names of this protein?
Fatty acid-binding protein 5, Differentiation-associated lipid-binding protein LP2, Epidermal-type fatty acid-binding protein, E-FABP, Fatty acid-binding protein, epidermal.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Synapse. Postsynaptic density. Secreted. Note=Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into nucleus (By similarity). Secreted by astrocytes, but not by neurons (By similarity).
Protein: YQ3E_SCHPO
Sequence: MPTTISLIIFTFLSLGDSWNDFPSSNVPVYNMVTGIYAKFMKNSPNWPLSRCWLFIPQFAVYPEYFILSIRNTRRRNVL
What are the official names of this protein?
Uncharacterized protein C188.14.
Protein: Y529_PSEAB
Sequence: MKQSSPTYLKHHFLIAMPHMADPNFAQTVTYLVEHNEQGAMGLVINRPSGLNLAEVLEQLKPDALPPARCQHIDIYNGGPVQTDRGFVLHPSGLSYQSTLELGELAMSTSQDVLFAIAAGTGPEKSLISLGYAGWEAGQLEAELSDNAWLTCPADPAILFDLPAEERLSAAAARLGVNLSLLTAQAGHA
What are the official names of this protein?
UPF0301 protein PA14_05290.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DGTL1_HISS2
Sequence: MKLQINSSWQERFLADPPREKDHRPPFRRDRGRILHSAAFRCLQAKTQIHAIGENDFYRTRLTHSLEVAQIGSSIVAQMKLIDSFISLAQQLKEDRAELQKQLKLILPSNDLIESLCFAHDIGHPPFGHGGEVALNYMMRHHGGFEGNAQTFRLLTKLEPYTPNAGMNLTRRTLLGVVKYPTILDRSSPQYHQGVIVDNVDSKYVKISAWKPGKGIFRDDLKMFEWLLEPLSENDRTLFGQYKKERTRPDEVLKTRYKSLDCSIMELADDIAYAVHDLEDAIVVGVVTFQQWQSAVEKLTECRSEWIVENVQSLSQKLFSELHYERKNAIGALVNYFITHVRWKINNGFSEPLLRYNAELPDEVIEVLTIFKHFVWEYVIKHVDTQRVEYKGQRMLTEMFQIFDSDPLRLLPRNTAMRWQKATETDRKRIICDYIAGMSDAYALRVYQQL
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: UVRD1_MYCTU
Sequence: MSVHATDAKPPGPSPADQLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTAVLTRRIAYLMAARGVGVGQILAITFTNKAAAEMRERVVGLVGEKARYMWVSTFHSTCVRILRNQAALIEGLNSNFSIYDADDSRRLLQMVGRDLGLDIKRYSPRLLANAISNLKNELIDPHQALAGLTEDSDDLARAVASVYDEYQRRLRAANALDFDDLIGETVAVLQAFPQIAQYYRRRFRHVLVDEYQDTNHAQYVLVRELVGRDSNDGIPPGELCVVGDADQSIYAFRGATIRNIEDFERDYPDTRTILLEQNYRSTQNILSAANSVIARNAGRREKRLWTDAGAGELIVGYVADNEHDEARFVAEEIDALAEGSEITYNDVAVFYRTNNSSRSLEEVLIRAGIPYKVVGGVRFYERKEIRDIVAYLRVLDNPGDAVSLRRILNTPRRGIGDRAEACVAVYAENTGVGFGDALVAAAQGKVPMLNTRAEKAIAGFVEMFDELRGRLDDDLGELVEAVLERTGYRRELEASTDPQELARLDNLNELVSVAHEFSTDRENAAALGPDDEDVPDTGVLADFLERVSLVADADEIPEHGAGVVTLMTLHTAKGLEFPVVFVTGWEDGMFPHMRALDNPTELSEERRLAYVGITRARQRLYVSRAIVRSSWGQPMLNPESRFLREIPQELIDWRRTAPKPSFSAPVSGAGRFGSARPSPTRSGASRRPLLVLQVGDRVTHDKYGLGRVEEVSGVGESAMSLIDFGSSGRVKLMHNHAPVTKL
What is the function of this protein?
DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity.  A minimal tail of 18 nt is required for activity.  Also highly efficient on nicked DNA.  Involved in the post-incision events of nucleotide excision repair, as well as in nitrosative and oxidative stress response and possibly in persistence in the host.  Inhibits RecA-mediated DNA strand exchange; this does not require ATPase activity.  When combined with UvrA greatly inhibits RecA-mediated DNA strand exchange.
What are the official names of this protein?
ATP-dependent DNA helicase UvrD1, DNA 3'-5' helicase UvrD1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.