PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_PARP8
Sequence: MTVKLTIDCMGGDHGPSVTVPAAVNFVRSHADAHLMLVGIESAIRAQLKKLKAADNPALTVVSASEIVAMDDPVEVALRKKKDSSMRVALNRVKDDEAQACISAGNTGALMAVSRYVLKTLPGIERPAIAFALPNPTGYTTMLDLGANVDCEPQHLLQFAEMGHALVAAVEGKERPSIGLLNIGEEVIKGNDIIKRAGELLRTSTLNFRGNVEGNDIYKGTVDVIVCDGFVGNVALKTSEGLAQMLSDIIKEEFGRSWLTKVMAVLALPVLLRFKKRVDHRQYNGAALLGLRGLVIKSHGSADAYAFEWAIKRGYDAVKNGVLERLARAMEENAGSLEQAKRDAGGPGSASQMASPIAGPVSGQPAEPYSAQSSKA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SIGK_MYCVP
Sequence: MTASVLVGAAARLPLVTAELDALLRQVAQRDAEAFAAFYDQTRARVYGLITRVLRDPGYSEETTQDVYLQVWRNAAGYDPSVGSALSWLLTLAHRRAVDRVRSEQAASTRESRYGAISVDPPSDHVADDVLLDDERRRVAGCLDSLTDVQRECIQLAYYDGLTYAQVADRLAANLATIKSRMRDGIRALRKCLGVA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigK, ECF sigma factor SigK, Alternative RNA polymerase sigma factor SigK, RNA polymerase sigma-K factor, Sigma-K factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: CRCB_ECOBW
Sequence: MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLTANLIGAFIIGIGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVFVNLLGSFAMTALAFWLFSASTAH
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYS_FRATO
Sequence: MLDAKYVKDNLQQVAEKLATRGYQFDIAEFEAQEQKRKHLQERTQDLQSQRNTISKEIGQKKAKGEDTSDIFAKVNQINEELKIIEKELKDLQDTINQTLLSMPNLPADDVPVGKDENDNVEIRRWGTPREFHPEAPAKDHSDIGEILKMIDFKAAAKVTGSRFMVLKNKIAKLHRALSQFMLDLHTEKHGYEELYVPYLVNNDSLYGTGQLPKFAANLFKLEGDFEYSLIPTAEVPITNLVRDEILDTETLPRYYTAHTPCFRSEAGSYGRDTKGMIRQHQFEKVELVHITTADKGEESLELLTSHAEKVLQKLNLPYRVMKLCTGDMGFSAKKTYDLEVWLPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIENYQQEDGSIMVPDALIKYMGGISVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBRH_CHICK
Sequence: MVHWSAEEKQLITSVWSKVNVEECGAEALARLLIVYPWTQRFFDNFGNLSSPTAIIGNPKVRAHGKKVLSSFGEAVKNLDNIKNTYAKLSELHCEKLHVDPENFRLLGNILIIVLAAHFTKDFTPTCQAVWQKLVSVVAHALAYKYH
What is the function of this protein?
The rho chain is the major early embryonic beta-type hemoglobin chain.
What are the official names of this protein?
Hemoglobin subunit rho, Hemoglobin rho chain, Rho-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATGT_NATPD
Sequence: MRDIFERRDGDAAGRIGELSVPRAGTTVETPALLPVVNPHIRTIAPAELESTFGAQILITNGYILYGSDEYRERALADGLHDLFDFSGAIMTDSGSFQLSEYGEISVTNEEILRFQRDIGSDIGTPVDIPTPPEASREQTAADLETTKARLEAAETVDTGEMLVNAPVQGGTYPDLREEAAEHAYGTTLDVFPVGAVVPLMNSYRYGDMIEAILGAKRGLGADAPVHLFGAGHPMMFALAVAAGCDLFDSAAYALYARDDRYLTVAGTDHLDDLEYLPCSCPVCADHTPAELQAEDDTERERLLARHNLHVSFQELRTIKQAIKKGNLLELVERRARGHPAMVDGYRALLEAADQLERDDPVSKGSFFYLSGESARRPEVKRHHDRLSRLSVDGDRVLLSEGGDNSRFDETWRLQPPFGPFPPALSDSYPLTAELPERLDDRAYEAAAKGVRRLVDDHPETEFAVAHWGWPDAALDSLPDGVELLRLGADSDHPERDSAQSDMDGDEPKEDYPPGEDENA
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: RPOC_ECO57
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BGLS_AGRSA
Sequence: MTDPNTLAARFPGDFLFGVATASFQIEGSTKADGRKPSIWDAFCNMPGHVFGRHNGDIACDHYNRWEEDLDLIKEMGVEAYRFSLAWPRIIPDGFGPINEKGLDFYDRLVDGCKARGIKTYATLYHWDLPLTLMGDGGWASRSTAHAFQRYAKTVMARLGDRLDAVATFNEPWCAVWLSHLYGVHAPGERNMEAALAAMHHINLAHGFGVEASRHVAPKVPVGLVLNAHSAIPASDGEADLKAAERAFQFHNGAFFDPVFKGEYPAEMMEALGDRMPVVEAEDLGIISQKLDWWGLNYYTPMRVADDATPGVEFPATMPAPAVSDVKTDIGWEVYAPALHTLVETLYERYDLPECYITENGACYNMGVENGQVNDQPRLDYYAEHLGIVADLIRDGYPMRGYFAWSLMDNFEWAEGYRMRFGLVHVDYQTQVRTVKNSGKWYSALASGFPKGNHGVAKG
What are the official names of this protein?
Beta-glucosidase, Amygdalase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: HBB_URSMA
Sequence: VHLTGEEKSLVTGLWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSADAIMNNPKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CWC22_CAEEL
Sequence: MSSSRSQSPETPKAASEEREEEEKESSEQPDTPKTSSEKSASRSQSPRESREVSQETETSENQEKIKEKDDGDDQPGTPNSYRSRETSPAPKRSKETRESESPEKSPVRSRSPRRSSARSPSRSPRRRRERSSERKQSEEPAPLPEKKKKEPLDILRTRTGGAYIPPAKLRLMQQQISDKQSEQYQRMNWERMKKKIHGLVNRVNAKNLVQIVRELLQENVIRSKGLLCRDIIQAQAFSPGFSNVYAALAAVINSKFPHVGELLLRRLIVQFKRSFRRNDRGVTVNVIKFIAHLINQQVAHEVLALEIMILMLEEPTDDSVEVAIAFLKECGAKLLEIAPAALNSVYDRLRAILMETERSENALDRRIQYMIETAMQIRKDKFAAYPAVIEDLDLIEEEDQIIHTLNLEDAVDPENGLNVFKLDPEFEKNEEVYEEIRKEIIGNADISDEDGGDELDDEEEGSDVEEAPKKTTEIIDNTDQNLTAFRREVYLTMQSSLDYQEAAHKLLKMKIPDSMQNELCAMLVDCCAQQRTYERFYGMLIERFCRLRLEYQQYFEKLCQDTYSTIHRIDITKLRNLARLIAHLLSTDAIDWKILADMKMTEEDTTSSGRIYIKYIFNELVEAMGMVKLHSRVTDPTLAHCFVGLFPRTNPNSARFSINFFTMIGLGGLTLELREWLAKGLKKKKGMLDQLKAESSSDSSSSSDSSDSSDSSDSDDSSDSSSDSSSSSESEPEPPKKKKKKNSEESSKKKEKENIGRRDRGDKRAERHRDQSVENKDKDRRRRQDSDENRRPERGDDRKDRSKDRRRQDSDDEDRKGRERREDSGERRRGDRDRRDRNKDQEDHREDRRDRSKDREDRRDRRRHDSDDDRKTRRDRSEERGGRRREVESDDRRRRR
What is the function of this protein?
Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly.  Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs.  Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity).  Plays a role in the nuclear retention of unspliced mRNAs (PubMed:23149939).  Plays a role in sex determination (PubMed:23149939).  Required for early embryogenesis and tissue differentiation.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22 homolog, Lethal protein 858, Nucampholin.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: TF2B_MACFA
Sequence: MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPTDFKFDTPVDKLPQL
What is the function of this protein?
General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II).  Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA.  Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex.  Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle.  Associates with chromatin to core promoter-specific regions.  Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element.  Modulates transcription start site selection.  Exhibits also autoacetyltransferase activity that contributes to the activated transcription.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis. Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle.
Protein: ECA1_ARATH
Sequence: MGKGSEDLVKKESLNSTPVNSDTFPAWAKDVAECEEHFVVSREKGLSSDEVLKRHQIYGLNELEKPEGTSIFKLILEQFNDTLVRILLAAAVISFVLAFFDGDEGGEMGITAFVEPLVIFLILIVNAIVGIWQETNAEKALEALKEIQSQQATVMRDGTKVSSLPAKELVPGDIVELRVGDKVPADMRVVALISSTLRVEQGSLTGESEAVSKTTKHVDENADIQGKKCMVFAGTTVVNGNCICLVTDTGMNTEIGRVHSQIQEAAQHEEDTPLKKKLNEFGEVLTMIIGLICALVWLINVKYFLSWEYVDGWPRNFKFSFEKCTYYFEIAVALAVAAIPEGLPAVITTCLALGTRKMAQKNALVRKLPSVETLGCTTVICSDKTGTLTTNQMAVSKLVAMGSRIGTLRSFNVEGTSFDPRDGKIEDWPMGRMDANLQMIAKIAAICNDANVEQSDQQFVSRGMPTEAALKVLVEKMGFPEGLNEASSDGDVLRCCRLWSELEQRIATLEFDRDRKSMGVMVDSSSGNKLLLVKGAVENVLERSTHIQLLDGSKRELDQYSRDLILQSLRDMSLSALRCLGFAYSDVPSDFATYDGSEDHPAHQQLLNPSNYSSIESNLIFVGFVGLRDPPRKEVRQAIADCRTAGIRVMVITGDNKSTAEAICREIGVFEADEDISSRSLTGIEFMDVQDQKNHLRQTGGLLFSRAEPKHKQEIVRLLKEDGEVVAMTGDGVNDAPALKLADIGVAMGISGTEVAKEASDMVLADDNFSTIVAAVGEGRSIYNNMKAFIRYMISSNIGEVASIFLTAALGIPEGMIPVQLLWVNLVTDGPPATALGFNPPDKDIMKKPPRRSDDSLITAWILFRYMVIGLYVGVATVGVFIIWYTHSSFMGIDLSQDGHSLVSYSQLAHWGQCSSWEGFKVSPFTAGSQTFSFDSNPCDYFQQGKIKASTLSLSVLVAIEMFNSLNALSEDGSLVTMPPWVNPWLLLAMAVSFGLHFVILYVPFLAQVFGIVPLSLNEWLLVLAVSLPVILIDEVLKFVGRCTSGYRYSPRTLSTKQKEE
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the endoplasmic reticulum lumen.  Also regulates manganese ion homeostasis by pumping it into endomembrane compartments.  Can also transport zinc.
What are the official names of this protein?
Calcium-transporting ATPase 1, endoplasmic reticulum-type.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SOP10_ARATH
Sequence: MERKKFSSKFIHLLIVFLLLCTFLSRTESALPYHHELFLGRKRMNYYKPNSAIGTPSSTSDHAPGSNGRKLMSIYRPNGDIFTGPSGSGHGGGRTPAP
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (PubMed:33514716, PubMed:34535661).  Inhibits root growth and regulates root meristems (PubMed:34535661).  Promotes ROS production and MAPK (e. g.  MPK3, MPK4 and MPK6) activation in a MIK2-dependent manner, thus leading to the up-regulation of immune-related marker genes (e. g.  WRKY30, WRKY33 and CYP81F2) (PubMed:34535661).
What are the official names of this protein?
Serine rich endogenous peptide 10, AtSCOOP10, Phytocytokine SCOOP10, Precursor of serine rich endogenous peptide phytocytokine 10.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Protein: CELF2_MOUSE
Sequence: MRCPKSAVTMRNEELLLSNGTANKMNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSSTSSALGALTSPVAASTPNSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGMAALNGGLGATGLTNGTAGTMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY
What is the function of this protein?
RNA-binding protein implicated in the regulation of several post-transcriptional events.  Involved in pre-mRNA alternative splicing, mRNA translation and stability.  Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing (By similarity).  Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle (By similarity).  Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB (By similarity).  Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs (By similarity).  Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA (By similarity).  Involved in the apoB RNA editing activity (By similarity).  Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury.  Modulates the cellular apoptosis program by regulating COX2-mediated prostaglandin E2 (PGE2) expression.  Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK (By similarity).  Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5 (By similarity).  Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs (By similarity).  Binds to apoB mRNA, specifically to AU-rich sequences located immediatly upstream of the edited cytidine (By similarity).  Binds AU-rich sequences in the 3'-UTR of COX2 mRNA.  Binds to an intronic RNA element responsible for the silencing of exon 21 splicing.  Binds to (CUG)n repeats.  May be a specific regulator of miRNA biogenesis.  Binds to primary microRNA pri-MIR140 and, with CELF1, negatively regulates the processing to mature miRNA (By similarity).
What are the official names of this protein?
CUGBP Elav-like family member 2, CELF-2, Bruno-like protein 3, CUG triplet repeat RNA-binding protein 2, CUG-BP2, CUG-BP- and ETR-3-like factor 2, ELAV-type RNA-binding protein 3, ETR-3, mETR-3, Neuroblastoma apoptosis-related RNA-binding protein, mNapor, RNA-binding protein BRUNOL-3.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with APOBEC1 and A1CF (By similarity). RNA-binding activity is detected in both nuclear and cytoplasmic compartments (By similarity). Accumulates in the cytoplasm after ionizing radiation.
Protein: RTEL1_DROYA
Sequence: MPESLIAGIPVHFPFEPYPVQRAYMEKVIQCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQQQMVKMEKADFTGLGGGAAGGDLSELAKTMGRANNWGVPKVIYASRTHSQLTQAMRELKRTAYANMRSVVLGSRDQLCIHPEVMREQGNSNKTNMCKLRVHSKTCSFQMRVESRKDHPDLRGPSIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAIEDVTHIMQVFASGESQDMGGDEPKDFTLDDLTLLKEMLLEFEKAIDAVVVENAVEGTTFPASMMYELLGKANFTYGNVATIVSLLDKLVQYLLVASQQMTIRKGGTFTMLSDLLTIVFANKEDVMSKVYASFKVHVQLEEVKQGHGKQQGGKQHGGWLGKGTIAAATGSIKVAKIINFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLIAELAIPVAQHLENPHIVDQSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVSRIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISVKKPIFLEPRSKDQFTSTMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLEANRTRENQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQLSKWIRGHLGDRPQCSPFGPIVRELRQFFKNAEANMKLPDERETDSPLETVCKTENEPIAAIPKVKREPGSNATFKSANESAIKVEMANSIKTWTPADYASAAGRKLGGAAPNAMDFMSRLDSNVSSIDFNCCMDSKSGSSGMVKIHKRERSSPTQPESSSQVSKKRYKLVENIKVEPSSSQVKEAPAERADFLRELRSLVTQDQFRRFGKALLEYKDGTYESFQALMVILLDVLSAPKVRYMLVGMRKYLKNEHKDEFDQKVGKL
What is the function of this protein?
ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.
What are the official names of this protein?
Regulator of telomere elongation helicase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRI_ECO7I
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFTVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: TRBC_ECOLI
Sequence: MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQLREKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPEEGLKRMLGETRHFGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGIRTVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK
What is the function of this protein?
Essential for F plasmid conjugative transfer, participates in F-pilus assembly.
What are the official names of this protein?
Periplasmic protein TrbC.
What are the subcellular locations of this protein?
Periplasm.
Protein: RRAA_ECOBW
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQD_ACICA
Sequence: MNKEQFDLNLVPTWRQGYRFQFEPAQNGFVILYPEGMIKLNESAGAIGQYIDGQQNVSAIIAQLKQKFGDISEIDQDVVDYMLVAKQQHWIDLV
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Coenzyme PQQ synthesis protein II, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: PAND_BACAN
Sequence: MFRTMMRAKLHRATVTEANLNYVGSITIDEDLMDAVNIVENEKVQIVNNNNGARLETYVIKGERGSGVVCLNGAAARLVQPGDKVIIICYGLVAEENIHKQEPKIAVLDDDNQIIEMLGAEKAGTIL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_CLOK5
Sequence: MPTISQLIRKGRKTVASKSTAPALKECPQKRGVCTVVKTTTPKKPNSALRKIARVRLTNGYEVSAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDSAGVADRLQGRSKYGAKRPKQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL28_STRZT
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKPKKVWASARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.