PharMolix/UniProtQA huggingface dataset:
Protein: AGUA_PSEU2
Sequence: MTTLNSTPRADGFHMPAEWAPQTQVWMVWPERPDNWRLGGKPAQAAHVAIAKAIARFEPVTVAVSAAQYDNARARLDMPNIRVVEMSSNDAWVRDSGPTFVINDRGEVRGVNWEFNAWGGFDGGLYAPWNLDSQLGGKVLEIERCPRYVTEGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHLTREQIETILGDYLAVDKVIWLPEGLFNDETDGHVDNFCCYIRPGEVLLAWTDDPEDPNYSRCHAALSILENTLDAKGRAFIVHKMPIPGPLFATEEECAGVDQVHGSQERNPSVRLAGSYVNFLIVNGGIIAPSFDDPMDEKAREILQKLFPEHEVVMAPGRELLLGGGNIHCLTQQQPAPHKN
What is the function of this protein?
Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
What are the official names of this protein?
Agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: Y1021_NEIG2
Sequence: MTEQKNKASLIEFPCAFPLKVMGAVHPEFEQAVLDTVRLHAPDTQAHHITTRPSSKGNYTGATVQVKVENQEQLDNIYRALTSHELVKVVL
What are the official names of this protein?
UPF0250 protein NGK_1021.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: GH109_STRCO
Sequence: MSQTPAVSRRLLLGSAAATGALATGIGSAAPVAAAEQAPRRRPGQKSMIGVPFAAHPTVRVAVIGLGNRGGGMITGWAAVPGCTVTAVCDIRADRAERAADRLESKGNPRPAEYGGSADSYARMLRRDDIDLVYIATPWEFHYEHGRAALLSGRHAVVELPVATELRQLWDLVDTSERTRRHLLLSENCNYGRNELAMLKAAHDGLFGDLTNGHGGYLHDLRELLFSDTYYTDSWRRLWHTRSTASFYPMHGLAPIAAAMDVNRGDRMTTLRATTTAPKGLADYRARFVPRDHPSWKETYINGDLVTCMIETAKGRTVRAEHDVSSPRPYSRINTLAGSRGIVEDYAGSAPTGARIYVEPDHGGHTWRDFETYRKEYDHWLWQKVGDDAANNGGHGGMDYVLQWRTVQLMRAGLVPDIDVYDSAAWCSPVPLSVTSLARGGRPVEIPDFTRGAWRERRPGLDSAPTDMPPAG
What is the function of this protein?
Glycosidase (By similarity).  Has no alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: Y972_PSEPK
Sequence: MGKPWFVYLVRAANGSLYCGISDDPQRRFAAHQKGQGARYFKTSPAQALVYVEQWPDKSAALRQERLVKRLRKSAKEALVASFGGLGEISPCGASADPPRLSAAP
What are the official names of this protein?
UPF0213 protein PP_0972.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: MNTP_METS3
Sequence: MDTSLISIIIIAIALAMDAFSVSLTKGFTQKNLTKSQILYYGLFFGFFQFIMPVIGYICGTTISSFVSTVAPWIAFFLLLAIGLNMIRESLDSDDEYIMDTFSFKELTLLAVATSIDAFAVGITFALLNMSLLLPCTIIGIVAFIFSISGIFIGKKLGNYFGDKFEILGGAVLILIGIKILLGY
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCUP_RHOPS
Sequence: MTQKLVTKPFIEVISGKRQASPPMWMMRQAGRYLPEYRATRTEAGSFLDLCFNPKLAAEVTLQPIRRFGFDAAIIFSDILVVPYALGRAVRFEVGEGPRLDPLNSPDLVGTLNGAIDLGKLEPVFEALRIVRSELAPETTLIGFCGAPFTVATYMVAGQGTSDQHPARLMAYQHPGAFAKIIDVLVESSIQYLLKQLEAGADVLQIFDTWGGILPPREFEKWCIEPTRRIVEGVRKVKPDAKIIGFPRGAGALLPAFIERTGVDAVSIDWTAEPKMVRDQVQTKVAVQGNLDPLLLIAGGSALDQGVDDVLKNFSAGRHIFNLGHGITPDASIAHVEQMVKRVRAFRG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_STAAR
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKGAYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEKVIEHAARAIEKFVETSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1G_BOVIN
Sequence: MADIDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Dephosphorylates RPS6KB1.  Involved in regulation of ionic conductances and long-term synaptic plasticity.  May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II.  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation.  May dephosphorylate CSNK1D and CSNK1E (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cleavage furrow. Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome, centromere, kinetochore. Nucleus speckle. Midbody. Mitochondrion. Cytoplasm, cytoskeleton, microtubule organizing center. Note=Colocalizes with SPZ1 in the nucleus. Colocalizes with URI1 at mitochondrion. Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleolus to nuclear speckles. Shows a dynamic targeting to specific sites throughout the cell cycle. Highly concentrated in nucleoli of interphase cells and localizes at kinetochores early in mitosis. Relocalization to chromosome-containing regions occurs at the transition from early to late anaphase. Also accumulates at the cleavage furrow and midbody by telophase.
Protein: GBG_CANGA
Sequence: MEVSQSQLDLKIKYLKLKRINELNDKLRDELQRERITASNACLQLIAYTTSTRDYALPTLWGYPPADTNHFRDFQTQHADDATCCTIM
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: TRUB_LEGPL
Sequence: MTTIESKCSIDGILLLNKPQGMTSNAALQKAKHLFGAKKAGHTGSLDPLATGMLPLCFGEATKICQYLLNADKSYETIGRLGSKTNTADCTGEVIFCIENYTVSHEELIATLEKYKGKTKQIPSMFSALKHKGTPLYRLAREGIEIERKARDIVISQLKLEQFDGECFTLTVSCSKGTYIRNLVEDIGDTLKAGAHMTKLHRLYTAGFENNRMYTLDELQDMPLSQRLACLIPIDQAVQHLTPVILSDSEVTAIRQGKVISNKTSAVEGEDLRLYGEQSQFIGIGQALIHGDIKAKRLVSFAL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: HUPD_RHILV
Sequence: MTIPYPLGPPPAPRILVLGIGNILWADEGFGVRAVEAFHKAYELSDNVTILDGGTQGLYLVQFVNEHDRLIVFDAIDYGLEPGTMKVVEDDEVPKFTGAKKMSLHQTGFQEVLSAADFMGHYPERLTLIGCQPLDLEDWGGPLTAPVRGVIPAAIETAVRVLRSWGVAVTARPEGAAVPPLLEHDIDFERYERRAEPAALNC
What is the function of this protein?
Not known.  Could be involved in the processing of hydrogenase.
What are the official names of this protein?
Hydrogenase expression/formation protein HupD.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: RK14_CHLSC
Sequence: MIQPKTHLNVADNSGARELMCIRIIGASNHRYAHIGDVIVAVIKEAVPNMPLERSEVIRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQEGNPRGTRVFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYP_LACJO
Sequence: MRQSKFFMPTLKEAPSDAVAKSHQLMLRGGYIRQVTAGVYAYLPLGYRVLRKAENIIEEEMDNINVPEMIMPHLLPATLWQESGRYKKYGAEMFKLQDRHGRESLLGPTHEETFTEIVAKNLKSYKQMPLALYQIQTKFRDENRPRFGLLRGREFVMLDGYSFAATREQLDEQFDDQKSAYLKIFNRAGVTVHPVIADSGTMGGKNSTEFQAPAAIGEDTIATNEKGTYAANLEMAKSIDTFKQEPEEAKDLAKVATPGMDTIEKLADFLKVPSTRIVKSILYIADDQKVLVLIRGDKEINEVKLGHILDADEVRTANADELVEITGSEKGGVGPINADWADKIIADETVKDLYNVVVGANETDYQYQNANLDRDFKVDEFADIRTANEGEPDPVDHLPLKFTTSIEVGHIFKLGTYYTDTMGADFLDNNGKAKPVIMGSYGIGVTRMLSAAVEQHLTENGIAWPKEIAPFAIHLIQMKMKDETQTKLAEKLEKELSAKYDVLYDDRNERPGVKFNDADLVGAPLRITIGRKAKDGIVEVKRPMDEKATEVNISDLDAVITKELG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_LISMC
Sequence: MLNDLYEEIKLRKTQPREGSYTNYLFDKGLDKILKKVGEEATEVVIAAKNNEQELIAEVSDLTYHLLVLLAEQNIPLSKIQAELQNREGKLSTTRDRKEINDL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPR_VIGRR
Sequence: MASNSDLVRAVESFLGVSLGDSVSDSLLLIATTSAAVVVGLLVFLWKKSSDRSKEVKPVVVPRDLMMEEEEEVDVAAGKTKVTIFFGTQTGTAEGFAKALAEEIKARYEKAAVKVVDLDDYAADDDLYEEKLKKESLVFFMLATYGDGEPIDNAARFYKWFTEGKDERGIWLQKLTYGVFGLGNRQYEHFNKIGKVVDEELAEQGAKRLVAVGLGDDDQSIEDDFSAWKESLWSELDQLLRDEDDANTVSTPYTAAILEYRVVIHDPTAASTYDNHSTVANGNTEFDIHHPCRVNVAVQKELHKPESDRSCIHLEFDISGTSITYDTGDHVGVYAENCNETVEETGKLLGQNLDLFFSLHTDKDDGTSLGGSLLPPFPGPCSLRTALARYADLLNPPRKAALLALATHASEPSDERLKFLSSPQGKDEYSKWVVGSQRSLVEVMAEFPSAKPPLGVFFAAIAPRLQPRYYSISSSPRFAPQRVHVTCALVYGPTPTGRIHKGVCSTWMKNAIPSEKSQDCSSAPIFIRPSNFKLPVDHSIPIIMVGPGTGLAPFRGFLQERYALKEDGVQLGPALLFFGCRNRQMDFIYEDELKSFVEQGSLSELIVAFSREGAEKEYVQHKMMDKAAHLWSLISQGGYLYVCGDAKGMARDVHRTLHSIVQEQENVDSTKAEAIVKKLQMDGRYLRDVW
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: LEUD_LISMC
Sequence: MEEIKVHIGKTVALMNDNIDTDQIIPKSFLKRIERTGFGEFLFDSWRYLPNRKPNPDFPLNAPDRQEATILITGDNFGCGSSREHAAWALLDYRFRVIIAGSYSDIFYMNCTKNGVLPIVLPREAREKLAKIAADENVTIDLPNQQVISSVGTYPFEIDATWKNKFINGLDDIAITFEHIDAIKAYEQKVDSI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FIM1C_BACO1
Sequence: MKQYKLMQVALLAILLFGWAGCSQNEEEVPGNVRNGIVLNVTDTGIISNEPSTRTEDTGFVTTFTQGDQIGLFAVKDGAILDEINNMPFTFNGSSWSGKPILYDDRLVGVNFYAYYPYQSEMTGKTDLIGDDFFAPLAAGWELTTEQSDQKAYAKQDLMTSNATALIGENGNYSLSFQLTHRMSLVVVKLPSTRYIFTDAEGVAMPEETPYVAMSVDVAFYLDNVEEGTKISPYYDAKKDEYRLLRKPSSENQIIGHYNDKQCTLDTAEKMKEGKYKRFVVDGGYKEVTHHLQVGDYYYADGSVVSGNEAEPAKDNCIGIVCWVGNPMPSVLYKDVAGTPYTATNDALLRSHPNCVHGLVMSLYTETGKFSPALTQSIHDWFMTTSFTSSYVSVTGYYDANENNKNKPLRFLGYNNSEVLDLYYDTFKTDFECFQYQDDCESSFPSPSITTGWYVPSSGELVALQDKDNSLESKLNTKLIKVSDKTMDISATYWSSTERNNKNMYIVTYSKTAGSAGTGGVKTNTYTYRFFLGF
What is the function of this protein?
Probably a component of the fimbrium tip.  Fimbriae are filamentous appendages on the cell surface that mediate cell adhesion and biofilm formation.
What are the official names of this protein?
Putative fimbrium tip subunit Fim1C.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. Mfa-like family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Probably synthesized as a palmitoylated precursor. Efficient export to the outer membrane and integration into fimbriae requires lipidation and subsequent proteolytic removal of the lipidated propeptide. Probably part of the fimbrium tip.
Protein: PRP39_XENLA
Sequence: MEKSPEHCAEGSPSPATESAPSATEPPLPSTEPPLPSTEPPLPSTEPPLPPLPPDFEKYWKSVQAYPEDFNTWTYLLQYVEQENHLFAARKAFDAFLAHYPYCYGYWKKYADLEKKNNNILEADEVYRRGIQAITLSVDLWMHYLNFLKETLDPADPETSLTLRGTFEHAVVSAGLDFRSDKLWEMYINWETEQGNLSGVTSIYSRLLGIPTQFYSLHFQRFKEHIQGHLPREFLTSEKFIELRKELASMTLHGGTNDDIPSGLEEIKDPAKRTTEVENMRHRIIEVHQEIFNLNEHEVSKIWNFEEEIKRPYFHVKPLEKAQLNNWKEYLEFELENGSNERIVILFERCVIACACYEEFWIKYAKYMENHSVEGVRHVYNRACHVHLAKKPMVHLLWAAFEEQQGNLEEARRILKNIETAIEGLAMVRLRRVNLERRHGNVKEAEHLLEEAMNKTKTSSESSFYAIKLARHLFKVQANVVKARKVLSNAIQKDKENTKLYLNLLEMEYNCDIKQNEENILAAFDKAIKSPMSIAMRVKFSQRKVEFLEDFGSDVNKLLDTYNEHQKLLKHQDIVKRKAENGLEQPEAKRLHAEEVSTAASVPVTTASMDATQSGYNYGSWYQYNYPANWNFGQYYNTPST
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing factor 39, PRP39 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRP39 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OM25_BRUNE
Sequence: MRTLKSLVIVSAALLPFSATAFAADAIQEQPPVPAPVEVAPQYSWAGGYTGLYLGYGWNKAKTSTVGSIKPDDWKAGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLEVKQGFEGSLRARVGYDLNLVMPYLTAGIAGSQIKLNNGLDDESKFRVGWTAGAGLEAKLTDNILGRVEYRYTQYGNKNYDLAGTTVRNKLDTQDIRVGIGYKF
What are the official names of this protein?
25 kDa outer-membrane immunogenic protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS18_SHEPC
Sequence: MARYFRRRKFCRFTAEGVAEIDYKDIVTLKNYITESGKIVPSRITGTSAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GUC1B_LITPI
Sequence: MGQHLSEESNKVEIDVAELQEWYKKFVVECPSGTLFMHEFKRFFGVQDNQEAADYVEHMFRAFDKNGDNTIDFLEYVAALNLVLRGKLEHKLKWTFKVYDRDGNGCIDKTELLEIVESIYNLKKVCRQGQDDRIPLLSPEQVVDRIFQLVDENGDGQLSLDEFIDGARKDKWVMKMLQMDVSPGSWINEQRRKSALF
What is the function of this protein?
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated.  This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure (By similarity).
What are the official names of this protein?
Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B.
Protein: SFSA_SYNFM
Sequence: MTDSAKPQNPDPGHESRRVAPLAGSPRSPFLIEFPEDSFTAVFLGREKRFLVEAERNGHLFQAHCNNSGSMLGLLRPGSDILLSVSPNPSRRLPYTLESIKLGSHWVGVNTLVPNRILRLAWDRGILPELIGYDRFQNEKTSGESRLDAFAEGPAGQVWIEAKNVTLVEDDVACFPDAVTVRGQKHMRELTALARAGRRAACFFLVQRPDASCFAPADFIDPVYAELFHAAVHAGVEIWPYEAVVTRQGIALGRRLKVVGH
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: VE6_HPV43
Sequence: MSARSCSQNARTIFELCDECNITLPTLQIGCIFCKKWLLTTEVLSFAFRDLRVVWRDGYPFAACLACLQFHGKISQYRHFDYAAYADTVEEETKQTVFDLCIRCCKCHKPLSPVEKVQHIVQKAQFFKIHSVWKGYCLHCWKSCMEKRRRSETMC
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RL20_CLOK1
Sequence: MARVKRAVNARKHHRKILKLAKGYYGGKSKLFKTANESVIRALRNAYVGRKLKKRDFRKLWIVRINAAARINGLSYSKFMNGIKTAGININRKMLSEIAINDPKTFTELVQVAKAQLNV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: BIOH_XYLFM
Sequence: MYIEVTGYGPALVLIHGWAMHSGVFAPLVEQLRPHHTLYLVDLPGHGYNHTTPTPLALPQVVHAIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLIMLAATPCFVRREDWPHAVEVSIFTQFAQDLKQNYTETINRFLALDTLGSTHAQSELRQLRKILNARHTPNTATLQAGLELLAHTDLRRAVIDLTPPSLWIAGQRDRLVPAASIQAATALAPSGQTELLTITGGGHAPFLSHANQMTAALQHFIATLP
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPS1_PENJA
Sequence: FVKNSGICETTPGVNQYSGYLSVGSNMNMWFWFFEARNNPQQAPLAAWFNGGPGCSSMIGLFQENGPCHFVNGDSTPSLNENSWNNYANMIYIDQPIGVGFSYGTDDVTSTVTAAPYVWNLLQAFYAQRPEYESRDFAIFTESYGGHYGPEFASYIEQQNAAIKAGSVTGQNVNIVALGVNNGWIDSTIQEKAYIDFSYNNSYQQIIDSSTRDSLLDAYNNQCLPALQQCSQSGSTSDCTNADSVCYQNIEGPISSSGDFDVYDIREPSNDPYPPKTYSTYLSDPTVVKAIGARTNYQECPNGPYNKFASTGDNPRSFLSTLSSVVQSGINVLVWAGDADWICNWLGNYEVANAVDFPGNAQFSALDLAPYTVNGVEKGQFKTVDNFSFLKVYGAGHEVPYYQPDTALQAFKQIIQKKPISST
What are the official names of this protein?
Carboxypeptidase S1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
Protein: PLSX_SHEPC
Sequence: MTSLTLALDAMGGDHGPHVTVPAALRALQLHSFLQIILVGDKTEIDVYLRQADPQLLSRIEVIHTDEVVSMSDRPVHALRTRKNSSMRLAIELVRDARASACVSAGNTGALMAMAKVLLKTLPGIDRPALVSCLPAVTQKPVYLLDLGANVSCDSETLFQFAVMGSVLCEAVDKKSRPKVALLNVGVEEIKGNDQVQQAAQLLQHTEQINYTGFIEGDEIYSGNVDVIVCDGFVGNITLKTSEGIAKLLVHQLKRGLTQGLFVRFLAKLIAPRIQAVLSQMNPDHYNGASLLGLRGIVVKSHGNADETAYLQAISLAVTEAQRRLPEMIKDRLESILLDINN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: AROL_SALPK
Sequence: MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQVVSEIIAALPPSTQRLQGDVYT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_HYDS0
Sequence: MKINFINLGCPKNLVDSENIMGFFKKENISSYHRADTVVINTCGFIEQAKRESIEEILKAIGDGKKVFVTGCLVYRYKEELQKEIPEAVFFENIKDLEGIELLQTPKRQLTTKHYAYLKIAEGCNRKCSFCAIPNIRGHHRSKSIEELVEEAIYLKEKGVKELIIVSQDTLYYQEDNSFKSIIKLLDALEKLDFPWIRLMYLYPNSISKDFIDYIDNSKSVLPYFDIPLQHISDNILKSMRRGYTKKDVFRLLEQINAMKHKKPILRSSFIVGYPTEEERDFEELLDFISQELFHFVGVFEYSHEEGTYAYQFDDKIPKEEKQRRYKEVFNLSQEILEEKNSALVGQEIDILIEKKDRARAFFQAPEIDGIVFLEKSSPKTGIIKKAKVIANIGTDLLVDI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPY57_ARATH
Sequence: MSTVYVLEPPTKGKVIVNTTHGPIDVELWPKEAPKSVRNFVQLCLEGYFDNTIFHRVIPGFLVQGGDPTGSGTGGDSIYGGVFADEFHSRLRFSHRGIVAMANASSPNSNGSQFFFTLDKCDWLDKKHTIFGKVTGDSIYNLLRLGEVDTSKDDRPLDPAPKILSVEVLWNPFEDIVPRVLAKTSEESAAEIKEPPTKPVKKLNLLSFGEEAEEEEKELAVVKQKIKSSHDVLNDPRLLKAEASDKERNASESKEVLSVREALNAKKEAAQKDKSFSVSDTVGNSDDDDDGEDETKFDAKMRNQVLSRRKEIGDTPSKPTQKKKSSSLKGREESTQRSDAVSSEDEKPRMEKLSLKKKGIGSEAKAEHMEKGDTDLQLYNASERARQLHKLKKRRLQGNEDSVLAKLEKFKQSISAKPFTSSNEPVVLTSSSEPVDNKEEDLSDWKNVKLKFAPERGKDKMSRRDDPDAYMVVDPLLEKGKEKFNRMQAKQKRREREWSGKSLA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Involved in plant response to pathogen infection by increasing PAD4 expression in absence of EDS1 up-regulation.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP57, PPIase CYP57, Cyclophilin of 57 kDa, Cyclophilin-57.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS15_PICMA
Sequence: MADADVDVGPVQPKKRTFKKFSYRGVDLDALLDMTSEELVKLFHARARRRFQRGLKRQPMALIKKLRKAKREAPSGEKPEPVRTHLRNMIIVPEMIGSIIGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGIGATHSSRFIPLK
What are the official names of this protein?
40S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.