PharMolix/UniProtQA huggingface dataset:
Protein: MTAD_DESVH
Sequence: MPLPCDTILQAALIVTQDDARTVIEDGAIAIHEGRIAAVGQRDAIVGNWHGVTVIDMGESLIMPGLVNAHTHASMTLLRGLADDLPLMDWLTGHIFPVEKGLTGELVELGALLGCAEMLRTGTTAFSDMYLIEDATLRAVDRAGLRCLAGEAIFAFPSPAYADPETAFDLVRAQHDRWKHHARAALAVAPHAVYTSTPAILARCRDLAEELGLPIHLHLAETATETAQCIEQHGARPVPYCDGLGLLTPRTTLAHCVDLTEGEIDLLAERGVTVAHCPESNMKLASGIAPATAMLGRGMTLGLGTDGAASNNSLNMFTEMTSCALLHKVHHMDPTCAPASAVLDMATRGGAHALHMQGIGRIEAGCPADIIALDLRAPNMQPIFNPASHLVYAATGHETRLTMVGGEVLYLDGCYTRFDMDDLLKEVRKARTWAMEQVRAAR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: Y120_STAHJ
Sequence: MTIEPKGKYMESRGIFLYINHNTRTTKGYYYVRKTTDDSKGRLKDDEKRYPVKMEHNQIIPTKPIPNDKLKKEIENFKFFVQYANFKDINDYKNGDISYNPNIPSYSAKYQLNNNDYNVKQLRKRYDIPTNQAPKLLLKGDGDLKGSSVGSKNLEFTFVENKEEDIFFTDAVQFTPSEDDES
What are the official names of this protein?
Putative uncharacterized protein SH0120.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
Protein: RL23_ALIB4
Sequence: MADITDIKAILYTEKTIELQENGVIVVQTSPRMTKNGLKEVFKEYFGVTPSKVNSLRQDGKVKRFRGKIGKRADFKKFYVTLPEGAAIANLSA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SPEH2_BACAN
Sequence: MEYSTFGKHIIVDLWGVDFSLLDDMYFLEHHLIHAADLSGAHVLNVSTKEFDPHGVTVLVLLSESHLSIHTYPEQNFAAIDCYTCGTTVEPQIAIDYIVSILKPNEMHIRRLIRGIGEIVNTD
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 2, AdoMetDC 2, SAMDC 2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: NS1_I02A3
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEKESDEALKMTIASLPALRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKTIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEGGRPSLPPKQKRKMARTTESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: ATPE_COLMA
Sequence: MALLTVNLNVVSAEESLFSGSIKSLQITGSEGELGIMPGHAPLLTSLKPGMALITKKDGSEEVIYLSGGMLEVQPNNVTVLADIATRAADLDEQAALEAKQRAEENMNANGADVDFAVAAAQLARAVAQLRVIQATSKHN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPB_STIAU
Sequence: MSAQVATVGKITQVLGPVIDVEFPPGGLPEVYTALKVTNTSISAEADNLTIEVAQHLGENMVRCISMDSTEGLARGQAVKNTGAPIQVPVGQGTLGRILNVIGEPVDERGPITSSQTWPIHRPAPTFVDQDVRVQAFETGIKVIDLLGPYTRGGKIGLFGGAGVGKTVLLMELIVNVAKERGGFSVFAGVGERTREGNDLYHEMQEGNVSTPRTWMESQCVLVYGQMNEPPGARARVALSALTIAEYFRDMEGHDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTEMGALQERITSTTKGSVTSVQAIYVPADDLTDPAPATTFAHLDATTVLNRAISELGIYPAVDPLDSTSRILDPNVVGPEHYAVARKVQGILQKYKELQDIIAILGMDELSETDKLTVARARKIQKFLSQPFHVAEVFTGAPGRYVELKDTIQGFKELAEGKHDDLPEAAFYMVGNINEAIEKARKLAAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLM2_HUMAN
Sequence: MWLLPALLLLCLSGCLSLKGPGSVTGTAGDSLTVWCQYESMYKGYNKYWCRGQYDTSCESIVETKGEEKVERNGRVSIRDHPEALAFTVTMQNLNEDDAGSYWCKIQTVWVLDSWSRDPSDLVRVYVSPAITTPRRTTHPATPPIFLVVNPGRNLSTGEVLTQNSGFRLSSPHFLLVVLLKLPLLLSMLGAVFWVNRPQWAPPGR
What is the function of this protein?
Probably acts as an activating receptor.
What are the official names of this protein?
CMRF35-like molecule 2, CLM-2, CD300 antigen-like family member E, CMRF35-A5, Immune receptor expressed on myeloid cells 2, IREM-2, Polymeric immunoglobulin receptor 2, PIgR-2, PIgR2, Poly-Ig receptor 2.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PLPHP_BUCAI
Sequence: MKKITIIAVSKNRNINNIEEAIRSGINNFGENYLQESLIKIENLKKYKNITWHFIGKIQSNKTKKIAQNFSWCQTVDREKIAVLLNKFRPKNLPPINVLIQINNLKELQNNRYIDQYQELAQLILSMPNLNLRGIMAVPSIKTNVIENNLQYEKIKTIFNRFKRQYSSVDTLSLGTSVDIKESLLATSNMVRIGRNIFNI
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: MNMA_STRSV
Sequence: MSDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYALTLGADYVATGHYAQVKRDQDGLVHMLRGKDNNKDQTYFLSQLSQEQLQKTMFPLGHLEKPEVRAIAERAGLATAKKKDSTGICFIGEKNFKEFLSQYLPAQPGRMMTLEGRDMGQHAGLMYYTIGQRGGLGIGGQHGGDNEPWFVVGKDLSQNILYVGQGFYHDNLMSTSLDASQVHFTKEMPEEFTMECTAKFRYRQPDSKVTVTVKGDKAVVNFDKPQRAITPGQGVVFYDGDECLGGGLIDRAYKNGQVLQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHB_CORK4
Sequence: MAVHAHPDDEALWTGGLLAHLSRRGADVRVVTCTLGEQGEVIGEPMQGLIADEADMLGGFRYRELEDSLRILGVNGVHHRPCVLGGVGCWRDSGMVGTPSADHPRAFVKSGQQAVDALKALMSEFCPDIVVTYGPDGGYGHPDHIRAHEITHAAVAELPHTSAPELGGDNTDLFSAVLARRHGGRETSADHGIPDPVVLWAVRGETALKQAGRAISRIPDGWVAPSGMDFSFVDGAAGAVDSASSEKTPDKITEPDLAFVPDDLVDLAVQLSDADIEAQANAMAAHATQLWIADGRQSWTNPESAWAVSDPTVAPKVFALSNRIAQPLMREEHYVVAYGGSGPWAKTTPARYAYDSSVVRARGRSAFSLDQADEGAAHDTSEQSGQRR
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: DAPA_SHESW
Sequence: MINGSIVALITPMNSDGSIDFASLERLVEFHIDQGTDAIVAVGTTGESATLPMSEHVTVVAQTVKFAAGRIPVIGGNGANATAEAIELTKSLSKVGVAGMLGVTPYYNKPTPKGLIAHYKAVAASTDIPQILYNVPGRTAVDMQPETVAELVGVSNIIGVKEATGDIARVKRLRELCGNDFKLYSGDDATAREFLLLGGNGVISVANNIVPKAFKAMCDAALAGNAELALSLDTPLRGLYSTLFCEANPIPVKWAAHRMGLIKCGHIRLPLTELSEQCHGLLIDAMTRAQIEVK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1367_YERPY
Sequence: MAALDPTLLILLALAALGILSHNMTVTLAILILIAIRITPLNSFFPWVEKYGLTIGVLILTIGVMAPIASGKISASEVLHSFVQWKSILAIVVGVAVSWLGGRGVSLMTHQPSVVAGLLVGTVLGVALFKGVPVGPLIAAGLLSLVIGKS
What are the official names of this protein?
UPF0756 membrane protein YPK_1367.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDGC_ECO55
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL23_MYCGI
Sequence: MANVVDPRDIILSPVISEKSYGLIEDNVYTFIVHPDSNKTQIKIAIEKIFKVKVDSVNTANRPGKRKRTRTGYGQRKATKRAIVTLAAGSKPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: XYLR_ECOLI
Sequence: MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
What is the function of this protein?
Regulatory protein for the xylBAFGHR operon.
What are the official names of this protein?
Xylose operon regulatory protein.
Protein: TIP20_SCHPO
Sequence: MMSQQLIDFIDSRTRHPYKSDEVEKFQQEVNELQLPDPNSLPILSEEEKRQAREDAAFRRSSEGLEDAWLDSAIPADPTPIFRDTVELLCVYQSFVKKSASLDTVANFLDFSTDFSTLSTKKDETEIAPDCLHYIAELLFQKKEREVKEKWKNELTEKLKTLFNWPAINPNLKESSKFESFFGFVRSIQSFKDSETGLPLFMQVYITPYVNQFRYHFMSQKQTNVLSKPEWFFEFLLKVFRSNRSFYMLMRDIKFFPGVPPFFTFINLLNNVAKEKLTHIIKYDDYLVHLVHETLQYSVRLEQHFHYTQDPLIIFLFEQNGTYDKWLGLETQLSLTKLEDIKIASDAWELESDQSDDFSSAVPTKMTVRFRDMIETTFSVLQNLPSLDYQFNFWRSVQLKPMMQYVNWLEAFYESHESSSSIHLPGSLQTDKSKFDIAEVERMCKLYSNFKLLMDWLDDIEDEDVYIRIGHKMGSENYAAFYQVKPRLSTLTNGSFRMILRAVSQTLRPLLDNYSDLDTWVIKEQLPGAALLSTSVSAEIVGFQSRLKEIIALLQKLLIGSSQCEAIYQIGTLVESWMIKIVMTHQFSVRGGVQFAMDAMQIVLEFSDYPLLKFERLMSTVELLSLESGENKLIKKLIIEINQKNYDFIDEFFKTKEITLSYEDALGVLYRRVDAWKD
What is the function of this protein?
Required for protein transport between the Golgi and the endoplasmic reticulum.  May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (By similarity).
What are the official names of this protein?
Protein transport protein tip20.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: TSC10_CANAL
Sequence: MWFSKTNFPVEGKTALIVGASQGIGVNLAERLYEKNCSTILVARTESKLQHQIQNIKEKYPESSAKISYAVADVSNYDECTRLWRTIDPADPDILFCCAGSSIPKLFQDLTKVDIESGIDINYKTVINVVHTGFKHALSNNTDNLEPHNFKKRSVVLFSSVVSFFPFIGYSQYAPMKSAIESLSIILRQELSPYNYRVTCVFPGNFQSEGFEEEQKTKPDITKKIEGPSNPIPGDECARLIIDQLDKGYDSITTDFIGWFLGCSVLGISSPRQWGFFQILVSFIVSLIAPIANWFINRDIKNSFKKTKKE
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase TSC10, 3-dehydrosphinganine reductase, KDS reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: DCT6_CAEEL
Sequence: MIESTTSHQDFQQRSMTGYALEHPSYRIRGALFRHQDDGRLLSGCGGDIEVIHALELERSQHTCLPVRVTNVVVFGSNDVVRLIQPIEGTEDVIVNGDYHVSIVQSVELFESSTVSKSRILKLPGKIIAVNAEKHSNTELLLVFLLETGIFHYSFCAHTSTHFQCIQAFRCNRPITSGLLWRDSGLLHVAYYDGFVRVGVVHEQYDDMLLVKRVAVNRNNLSVLLDVVFEEIGRIQKFEDTEKQRREDMLTTSKSLSDKLVAEEEVVEGDTTNDDFAKLKIEFKNQSIRCERVSQRLTSLRKLITIIKSALDMNDQIEQMISLLVDELSELEKLEQLCKEVERTGNQNLIGKSWIAVEEKQMVVEELIAKVNSDQIKKHSDVWEQKIDQIIDQLNGCSEAAKDMRLIISQNIFEHRGDKKDVFTHFVLDAQSRDITLYCLSGLTTMAIYPRKGKRVASISLDASFATCLTAACAMKSAEGVYVADQNNVFPTYFYRNRPKAGKGEKRYLDAGNQLQLPTFDSISSILVEPHQMILGSVTGGLLHLSFDFASNYEHFVVASSILAHPISSGSVNCIKLLATGESLLALHCTDTEIVVSEKDQERWHRVTHHTGGAHAIAVTPFSVDERGAFAVVASDTFVRLKVLQYAEESLIGLHDLGESRAEDENGHPIEVLNVSLDPSMQYRQLPCKLRYAVGFADKAIRTYVALLTGQHDFNVQEKFIAQIEPLFNVQNMICFHGRPMGCYVSCAKTLQIWNDLDRHQQKKLKSERMQLLKLSSSVTSMERAEGYLLLGFADDRLSIYEEKGNGAVDLVGTVDDWHKGLNDRIVMSLRTRASKTSCGTRLFIHSLTAHHIVIHTVLVTASKIEQHDFIVAHEHSMSQPIGFEFVSYKYFEFLVYGRGISNEKLSIEDRKRMDNFRDFEFN
What is the function of this protein?
May have a role in tumor suppression.
What are the official names of this protein?
Protein dct-6, Daf-16/foxo controlled, germline tumor-affecting protein 6.
Protein: FHIT_HUMAN
Sequence: MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYFQ
What is the function of this protein?
Possesses dinucleoside triphosphate hydrolase activity (PubMed:12574506, PubMed:15182206, PubMed:8794732, PubMed:9323207, PubMed:9576908, PubMed:9543008).  Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP (PubMed:12574506, PubMed:15182206, PubMed:8794732, PubMed:9323207, PubMed:9576908, PubMed:9543008).  Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP (PubMed:8794732).  Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate (PubMed:18694747).  Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:18694747).  Exhibits adenylylsulfate-ammonia adenylyltransferase, catalyzing the ammonolysis of adenosine 5'-phosphosulfate resulting in the formation of adenosine 5'-phosphoramidate (PubMed:26181368).  Also catalyzes the ammonolysis of adenosine 5-phosphorofluoridate and diadenosine triphosphate (PubMed:26181368).  Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5 (PubMed:18077326).  Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways (PubMed:16407838).  Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis (PubMed:15313915).  Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake (PubMed:12574506, PubMed:19622739).  Functions as tumor suppressor (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: HTPX_BRUO2
Sequence: MNMTKTAMLIALMTVMFMSIGYLLGGGGGMMIALVIAVAMNLFGYWNSDKMVLRMYNAQEVDERSAPEYYRMVSGLAANAGLPMPKVYIIHEDQPNAFATGRNPENAAVAATTGLLNRLSPEEVAGVMAHELAHVQNRDTLTMTIVATLAGAISMLGNFAFFLGGNRENGNGVMGVVGTLLAMIVAPFAAMIVQMAVSRTREYAADKRGAEICGNPLWLSSALGKIARGAKVIPNEEAEHNPATAHMFIINPLSGRGADNLFSTHPDTDNRIAALEQMAAEMGIRSAAMTARAAAPSQNSGPWGQRSDNAGGNSNGGSRYRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LV1A_BUTOS
Sequence: MMKLVLFGIIVILFSMIGSIHGSDPPGNYPLNTYGNKYACTILGENDFCQKICKVHGVQYGYCFNSRCWCEYLEEKDVNIWDAVKRHCKNTILYPKGK
What is the function of this protein?
The edited BmKBTx-like, similar to beta-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Lipolysis-activating peptide 1-alpha chain, BoiLVP1-alpha, LVP1-alpha, Putative beta-like toxin Tx458, BoiTx458, Putative beta-like toxin Tx651, BoiTx651, Putative beta-like toxin Tx764, BoiTx764, Putative beta-like toxin Tx814, BoiTx814.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PETL_AETGR
Sequence: MLTLTSYFGFLLAALTITSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS11_LEPCP
Sequence: MAKAPVNNAARRVSKKVRKNIADGVAHVHASFNNTIITITDRQGNALSWASSGGQGFKGSRKSTPFAAQVAAEVAGRAAQEQGIKNLDVKIKGPGPGRESSVRALASLGIRIASISDVTPVPHNGCRPQKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DCYD_ESCF3
Sequence: MSLQNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPLAMGGNKVRKLEFLAADALREGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTQAENYLSNGNRLLLDLFNVQVEMCAALDDPDAQLQELATRIEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNLSSVVVASGSAGTHAGLAVGLEHLLPETELIGVTVSRSVADQKPKVVALQQAVARELELSAAAEITLWDEYFAPGYGTPNEEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDQGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: HSCA_PSEMY
Sequence: MALLQIAEPGQSPQPHQRRLAVGIDLGTTNSLVAAVRSGLAEPLADGDGKVILPSAVRYHPQHVEVGESAKLAAASDPFNTVLSVKRLMGRGIADVHQLGEQLPYRFAAGESHMPFIETVQGAKSPVEVSAEILKTLRLRAEQTLGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYGLDQKAEGVVAIYDLGGGTFDISILRLTGGVFEVLATGGDSALGGDDFDHAIADWIIQQAGISSDLDPSAQRSLLQAACAAKEGLTNADHVELSHGDWRGTLSREQFEALIEPMVARSLKACRRALRDSGVELEEVSAVVMVGGSTRVPRVREAVGELFGRTPLTNIDPDQVVAIGAAIQADTLAGNQRGEGEELLLLDVIPLSLGLETMGGLMEKLIPRNTTIPVARAQDFTTYKDGQTAMMIHVLQGERELIADCRSLARFELRGIPPMVAGAAKIRVTFQVDADGLLSVAARELGSGVEASIQVKPSYGLTDGEIARMLQDSFQNAGDDKAARALREQQVDAQRLIEAVEAALQADGERLLDAEEREVIELQVQELRDLLASNDGLAIERQSKRLSQVTDAFAARRLDSTVKAALAGRNLNEIEE
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YNAN_ECOLI
Sequence: MLRNRARRLDYKIMR
What are the official names of this protein?
Protein YnaN.
Protein: NRM_DROPS
Sequence: MATFAKVMLLLSSVATFGYTFFVVGKLMLFLSTPRSISKAHTWIFNLLDNKSRLETAYGPIVFDTLYLIGFIFQHSFLKSALVKNLWRKLGLAAAERTIYSLTSSICLHYLLKNWLPAQSIVLWQVDVDESAPLWWTFVVTHGLGWAVIFGGSLIMDLPELLGVKQVYYDLKEYGEPVAYKSSELRNLYSHVRHPSFVGLSVILFATNVMSLDRLLLASLLTVYMYVAWSTDDKDVAYQKQQLRNKKHELKAQ
What are the official names of this protein?
Nurim homolog, Nuclear envelope membrane protein, Nuclear rim protein.
What is the protein family that this protein belongs to?
Belongs to the nurim family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: 3SO8_OPHHA
Sequence: MKTLLLTLVVVTIVYLDLGYTTKCYNHQSTTPETTEICPDSGYFCYKSSWIDGREGRIERGCTFTCPELTPNGKYVYCCRRDKCNQ
What is the function of this protein?
Antagonist of muscle (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and neuronal (alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2, alpha-4-beta-2/CHRNA4-CHRNB2) nicotinic acetylcholine receptors (nAChR) (PubMed:20071329).  The highest affinity is for human alpha-7/CHRNA7 nAChRs (IC(50)=180 nM), compared to human alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE nAChR (IC(50)= 550 nM), alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (IC(50)=500 nM), and alpha-4-beta-2/CHRNA4-CHRNB2 nAChR (IC(50)=2. 6 uM).
What are the official names of this protein?
Haditoxin, Muscarinic toxin-like protein 3 homolog, MTLP-3 homolog.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group VIII (haditoxin) sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YR422_MIMIV
Sequence: MELPNRYSDLFVTEKARDFWCFTRNSMLYYMLLRSRNLNNILDEYIQCMNQFCGFYSMRIPKNKYNDQILTYSYPHLRSFEEICLDNVDKNYISTGDFKEMRIFYEQLLKFVDKCIGRKYKYGHKFNLIENNKIHQIAKEKTSKLLDKCPYNNVYVKIPKNVFNTEQYKEKNIVNTRYINDKNNIILMFNNNHNKFTFLTLWNITECIDSFSYFRIVKCIDQDDTVSIEYID
What are the official names of this protein?
Uncharacterized protein R422.