PharMolix/UniProtQA huggingface dataset:
Protein: VIF_HV1A2
Sequence: MENRWQVMIVWQVDRMRIRTWKSLVKHHMYISKKAKGWFYRHHYESTHPRVSSEVHIPLGDAKLVITTYWGLHTGEREWHLGQGVAIEWRKKKYSTQVDPGLADQLIHLHYFDCFSESAIKNAILGYRVSPRCEYQAGHNKVGSLQYLALAALITPKKTKPPLPSVKKLTEDRWNKPQKTKGHRGSHTMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: RNL2_LENED
Sequence: ISSGCGTTGALSCSSNAKGTCCFEAPGGLILQTQFWDTSPETGPTDSWTIHGLWPDNCDGSFSEDCDPSRDYTGISSLLTAQGASDTLQFMNQFWLNDPDDGSNEELWEHEWATHGTCYSTLQTSCLPEGSPKGAEAVAFFEQVVTLFKTLPTYEWLTNQGIKPSSSTTHTYSALTAALEAEAGVIPALNCDGSDLDEIYWYFHLRGSVIDGEFEPISAPEKGDCPSSGIKWLPKNNEK
What is the function of this protein?
This is a base non-specific and adenylic acid preferential ribonuclease.
What are the official names of this protein?
Ribonuclease Le2, RNase Le2.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: SYD_STAAN
Sequence: MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_PHOPR
Sequence: MKQFEGIKFIAFDLDGTLLDSVPDLAEAADKAMQALGRDRVTVEQVTTWIGNGADILIGRALSQSIELDPELDLALHQEARALFDRFYDEGGHKQSHLYAGVKETLAAFHQANIPMAIVTNKPAQFVPHLLEQHGISEYFVDVIGGDTFPLKKPDPFALHWLMEKHQLAACEMLMIGDSRNDILAAQAATCHVVGLTYGYNYGQPISASNPDVVLDQFSQLIDVVKLAC
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: YCJF_SHIF8
Sequence: MTEPLKPRIDFDGPLEVEQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGIQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTVRLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TFE_SACS2
Sequence: MVNAEDLFINLAKSLLGDDVIDVLRILLDKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKTRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTDKIKSFLEQKIRQIEEEIDKETKLGANKNH
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: MDH_DESRM
Sequence: MKRKKITIVGAGNVGATCAHWAAAKELGDIVLIDVAEGIPQGKALDLMEAAPVEGYDSVIIGTNDYADTADSDVVVITAGVARKPGMSRDDLLNINAGIVRKVTEEIVKYSPNAYLLIVTNPVDVSAYIAYKASGFSANRVFGLSGVLDSARFRTFIARELNVSFEDVISFVLGGHGDDMVPMVRYTYVGGIPVEKLIPTDRLEAMVERARKGGAEIVNYLKTGSAYYAPSASVMQMAECILKDKKRILPVSAFLQGEYGESDVFSGVPAIIGGDGVEKIIELDLDDEEMAALRKSINSVRNNISKLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: GLMU_BORBR
Sequence: MLNVVILAAGLGKRMQSDLPKVLHTLAGRPMLDHVIGSARQLQPARIIVVVGHGADRVKAAFEGLPGLQFALQQPQHGTGHAVQQAVPQLLEGDGEDDVTLVLYGDVPLVQPATLQNLLQARGRGVAVLTEVLADSTGYGRIVRDAQGQVCRIVEHKDASEAERAIKEVNTGILAAPTARLKDWLGRITNDNAQGEYYLTDVIGLAVGDGVPVGAAQPGASWETLGVNSRVQQAQLERAWQSELARRQLEAGVTLADPARFDVRGTLSCGRDVFIDVGCVFEGTVTLGDGVRVGPHCVLRDVAVQAGARIEAYSHLQQAKVGQEAVVGPYARLRPGADLGERSHVGNFVEIKNSVLQADSKANHLAYIGDADIGARVNVGAGTITCNYDGVNKHRTVIEDDAFIGSDTQLVAPVRVGKGATLGAGTTLTKDAPAGQLTISRARQSTIEGWKRPVKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1725_ARATH
Sequence: MRFSWKNICLPISCINNTNQKKTTTTNPPKEKLLLLSRQTSVPSRVYMSDFSNSTISLNDFSNSFFINIHIFTYEELKTITQGFSKYNFLGEGGFGEVYKGFVDDSLKTGLKDQPVAVKALKREGGQGHREWLAEVIILGQLKHPHLVNLVGYCCEDDERLLVYEYMERGNLEDHLFQKYGGALPWLTRVKILLGAAKGLEFLHKQEKPVIYRDFKPSNILLSSDFSSKLSDFGLATDGSEEEDSNFTKSVMGTEGYAAPEYISAGNLTTMSDVFSFGVVLLEMLTARKAVEKYRAQRGRNLVEWARPMLKDPNKLERIIDPSLEGKYSVEGIRKAAALAYQCLSHNPKSRPTMTTVVKTLEPILDLKDIQNGPFVYIVPVAGVSEVHEIKCKDDVKVVKEETEKDAKVFPRHRAGRRNRRKHKAMRSRAVYSDTALYKSLGTSLYNPAN
What are the official names of this protein?
Putative receptor-like protein kinase At1g72540.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SSB1_STAAS
Sequence: MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYENKEGQRVYVTEVVADSIQFLEPKNTDDNQQDLYQQQAQQTRGQSQYSNNKPVKDNPFANANCPIEIDDNDLPF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: RECX_TREPA
Sequence: MGTRPTDEQYGAVCFACRCYEAECVAVRLLARSETSAQQLGFKLLKRGFEKRVVESVFPVLKRYSWLDDTRFARAWLRNRVDSRPASRAQLLGELKRRGVSHADAEGALDLLFQEQDEETLCLRLLEKLRRRGYGPHTLQRALQRRQFSPSLVRRCLAVETEGA
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_LACGA
Sequence: MTKLTDEVKKRRTFAIISHPDAGKTTITEQMLLFGGVIRSAGTVKARKSGHYATSDWMAIEKKRGISVTSSVMQFEYQGKRINILDTPGHQDFSEDTYRTLMAVDAAVMVIDSAKGIEPQTKKLFKVVKKRGIPIFTFMNKLDRDGREPLDLIAELEDLLGIEGVAMNWPIGMGKQLKGLYDIANNRVELYRKDDDDRYLPLDKNGKLAEDEPLAQDSLYQSTLDDIDLLKEAGNTFDKEKILKGDQTPVFFGSALTNFGVETFLDSFVNLAPAPQEHIVNGDEKLAADDPEFSGFVFKIQANMNPNHRDRIAFVRIGSGEFKKGIDVTLARTGKPVRLNNATEFMSSERVQVSDAVAGDIVGLYDTGNFQIGDSIYAGKKKIVYPALPQFTPEIFMRVTAKNVMKQKSFHKGMNQLVQEGAIQLYRGYSTDDYILGAVGQLQFEVFSFRMKNEYNSEVELHTLGNRVARWINPDQLDPKMSSSRNLLVKDRDGEPLFLFENAFAERWFKDKYPDVELTSRL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRNH4_ARATH
Sequence: MAKAEENLRDKCRWSLGGMTALVTGGSKGLGEAVVEELAMLGARVHTCARNETQLQECVREWQAKGFEVTTSVCDVSSRDQREKLMENVASIFQGKLNILVNNAGTGITKPTTEYTAQDYSFLMATNLDSAFHLSQLAHPLLKASGSGSIVLMSSTAGVVHINVGSIYGATKGAMNQLAKNLACEWARDNIRVNSVCPWFIATPLYLNDEELKKEVERKTPMGRVGNANEVSSLVAFLCFPAASYITGQTICVDGGFTVNCFSFKPVL
What are the official names of this protein?
Tropinone reductase homolog At2g29170.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: CAD1_ENTFL
Sequence: LFSLVLAG
What is the function of this protein?
Involved in the conjugative transfer of the hemolysin plasmid pAD1.
What are the official names of this protein?
Sex pheromone CAD1.
Protein: TEAD2_HUMAN
Sequence: MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
What is the function of this protein?
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.  Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3').  May be involved in the gene regulation of neural development.  Binds to the M-CAT motif.
What are the official names of this protein?
Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y614_METJA
Sequence: MVMFMVFRILGRMTKIEKEIKEEEAKYDLIIKNEAKIEPIVAEEDMEFKQGDIKPIRIKKIKIPPMSVLLICPYGRHRVGHVVAVGEEVPMPIDVEREVDMAMFACGFEGEVKKGDLIGMLLILAAEKRE
What are the official names of this protein?
Uncharacterized protein MJ0614.
Protein: SDC4_PIG
Sequence: MASPRLLALLLLLVGAFNAAAAESIRETEVINPQDLLEGRYFSGDLPDDEDVGGPGQEPDDFEWSGSGDLEGPEDKHMLPEVTHPLVPLDNHIPERTGPGGRVPTEPKELEENEVIPKRMSPFDGDEDVSNKVSMSSTAQGSNIFERTEVLSALIVGGIVGILFAVFLVLLLVYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
What is the function of this protein?
Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
What are the official names of this protein?
Syndecan-4, SYND4.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form.
Protein: SYA_MYCUA
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLGQRTPPYATATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWALLTNSVADGGYGLDPEKLWATVYLDDDEAAGLWREVAGLPADRIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPDYGPEGGPVVNEDRYLEIWNLVFMQNERGEGTTKEDYEILGPLPRKNIDTGMGVERVALILQGVPNVYETDLLRPIIDLVAARAPRGYDQGNHADDVRYRIIADHSRTAAILIADGVSPGNDGRGYVLRRLLRRVIRSAKLLNIDTAIVGDLMATVRDAMGPSYPELASDSDRINRIAVAEETAFNRTLASGSRLFDEVAGATRSSGVSVVSGSDAFTLHDTYGFPIELTLEMASEAGLTVDEGGFRELMAQQRRRAKADAAARKHAHADLTAYRELVDAGPTEFTGFDELTSEARILGIFVDGKRVPVVAHGQAVDADRVELVLDRTPLYAESGGQIADVGTISGTGSGSSARAAVTDVQKIAKTLWLHRVNVESGEFVEGDGVVAAADAGWRKGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTEEQRGQIEEVTNQAVQADFAVHTFTEQLEKAKAMGAMALFGECYPDEVRVVEIGGPFSIELCGGTHVATSAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVASLVERLKAAEKELERARLASVRAAAVNAAAGAERIGNVRLVAQRMSSEMTPADLRTLVGDIRGKLGSDPAVVALIAAPAGGESSTVPYVVAANQAAQGLGLGANELIKHLAAAVDGRGGGKADLAQGSGKKPAGIAAALEALRAEIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA12_CONMA
Sequence: MGMRMMFTVFLLVVLATTVVSFPSDRASDGRNAAANDKASDVITLALKGCCSNPVCHLEHSNLCGRRR
What is the function of this protein?
Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them.  This toxin blocks neuronal mammalian nAChRs (alpha-6/alpha-3-beta-2-beta-3 (0. 39 nM) > alpha-3-beta-2/CHRNA3-CHRNB2 > alpha-3-beta-4/CHRNA3-CHRNB4 = alpha-4-beta-2/CHRNA4-CHRNB2) (PubMed:15005608, PubMed:20145249).  Also exhibits inhibition of D. melanogaster alpha-7/CHRNA7 nAChRs (PubMed:25466886).  In addition, inhibits alpha-6/alpha-3-beta-4 (CHRNA6/CHRNA3-CHRNB4) nAChR with a higher potency on human (IC(50)=1. 49 nM) than on rat receptors (IC(50)=31. 5 nM) (PubMed:33523678).  Its binding to alpha-3-beta-2/CHRNA3-CHRNB2 nAChR is prevented by alpha-conotoxin Lt1a, suggesting that the two toxins have overlapping binding sites (PubMed:20145249).  In addition, both toxins have distinct nAChR binding mode (PubMed:20145249).  In vivo, inhibits Ehrlich carcinoma growth and increase mouse survival (PubMed:32272633).  These effects are greatly enhanced when the toxin is applied with the non-selective cyclooxygenase inhibitor indomethacin (PubMed:32272633).
What are the official names of this protein?
Alpha-conotoxin MII, Alpha-Ctx MII, Alpha-MII.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPB_HAEIN
Sequence: MNNSLIVRQLGLQDYQEIWHKMQDFTDTRNAETQDEIWLVQHYPVFTQGQAGKPEHLLQRSEIPVVQSVRGGQITYHAPGQQVMYVLIDIKRHKNLNVRQLVTALEQTVVKTLAEYGIESYPKPDAPGVYVDGKKICSLGLRIRRGCSFHGLALNINMDLNPFHYINPCGYAGLEMCQLADFVNQDKADCDNVSAKLIKHFANLLGYNITTL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHD6_SCHPO
Sequence: MKIIIDTDPGQDDAITALLAIASPEIELLGVTTVAGNVPVSMTTRNALQMLDLAGRPDIPVYAGSNKPLLRAPITATHVHGASGFEGAVLPPPSRKENEGHAVDFIIDTLRNNEPGTITICTIGPLTNIALALNKAPEVIQRAKQIVMMAGAFSEVGNITPAAEFNIYVDPHAAQMVLSSGIPIVMMPLDITHQLHTSAKRIARMEALPNRVGPVVAAWLRMEKAYEAKKYGTDGGPLHDPNTVMWLLRPDIYSGRKVNVQIETQSELTMGMSVVDWWQVGLLPANVTFLRTVDDDEFYEVLIERLGRLP
What are the official names of this protein?
Uncharacterized protein C1683.06c.
What is the protein family that this protein belongs to?
Belongs to the IUNH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMA_CHLP8
Sequence: MTKVEYKHTHIAAKKKLGQNFLLDKNIPRKIVRESGIKEGDLVLEIGPGFGALSTAILEVMPSFTAIEKDPELARFIREEHPEINLIEGDFLKVPLEPLTGSGKLAVLGNIPYSITSPILFRLLDNRHLIESATLMMQHEVAQRITAVPGTKEYGILAVQMQAFCDVKYLFKVGRAVFKPRPEVDSAVIRLVPKAQNPVEDSEGFRTFVRRAFHQRRKTLWNNLKEYYNTSEVPAETLKLRAEALTVEGLIELFEKLTPIDHALNDPETRNGIE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_ARTS2
Sequence: MTLEFSTLGLAPDFVDYMKGWDTQRELHDKVVAAEAPSTVLLLEHAAVYTAGKLTEDHERPFDGTPVVAVDRGGKLTWHGPGQLIAYPILKLKNRSGIRDYVERLEAVMIAVMADYGINAERIKGRAGVWIKADSKGPDRKIAAIGIRVLDGVTMHGIAINCNNDLAPYAQIIACGITDAGVTTMSIEAGRTITPGDIAERVVEEFRKHEEALVSSPEGALL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_LACPL
Sequence: MATRKTTRRRRVKKNIESGVAHIHSTFNNTLVMITDMQGNAIAWSSAGSLGFKGSRKSTPFAAQMAAEAAAKASMEHGMKTVEVAVKGPGSGREAAIRALQATGLEVSAIRDVTPVPHNGSRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TSAD_SHEHH
Sequence: MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALADADMTIEDLDGIAYTKGPGLIGALLVGACVGRALAFSWDKPAIGVHHMEGHLLAPMLEDDVPEFPFLALLVSGGHSMLVGVEGIGRYTVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLSKLAAKGVPNSYRFPRPMTDKPGLNMSFSGLKTFAANTIAAEPKDEQTRANIACAFEEAVVDTLGIKCKRALKQTGYKNLVIAGGVSANTRLRASLSEMMQGLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEDLAVKGQPRWPLDTLEPVD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL1R2_CHLAE
Sequence: MFRLYVLVMGVSAFTLQPAAHTGAARSCPVRGRHYKREFRLEGEPVALRCPQVPYQLWASVSPHINLTWHKNDSARMVPGEEETRMWAQDGALWLLPALQEDSGTYICTTRNASYCDKVSIELRVFENTDASLPFISYPQILTLSTFGVLVCPDLREFTRDKTDGKIQWYKDFLPLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRNIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHVESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTRKDLNMVFKCFVRNTMGFQTLRTTVKEPPPTFSWGIVLAPLALAFLVLGGIWMHRRCKHRTGKADGLTVLRPHHQDF
What is the function of this protein?
Non-signaling receptor for IL1A, IL1B and IL1RN.  Reduces IL1B activities.  Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1.  Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B.  IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.  The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity).
What are the official names of this protein?
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
[Isoform Short]: Secreted. SUBCELLULAR LOCATION: [Isoform Long]: Cell membrane; Single-pass type I membrane protein.