PharMolix/UniProtQA huggingface dataset:
Protein: STRP_DICDI
Sequence: MDTASISSTSSNSKSSKEQIKYTFTDFDNDIKNEINELYSYSELSILKKSNISNQFYHDLHEYTSKNKWRDLTDIEKIDYLQHLIGFFELSMKGQDNYNRYLLKSRFIWYIAQGVRDETHDRKDQLHQSKLNCILLREINALPIILKTLVLSSQISNETLRNQQQQQQQQQQQQQQQQQQQQQQNENEGSGEGGTNFTTTTTTTTTTTTANTFISHGKRNNIIKNNSGSVSGVIKNINSNGTLSSSMKVNVKRADLLMSILLDIIYLIIINNKDDELFKEEIFESLEGCNNNNNNNNNYNNNILGKNNNNGTNCDNPNLISIILQLLSEFNEIDGNLYPIKKILMVLWKSLTIFMGGLEDLDRLKQERLDNVGYKKGTPKTRSYDISNFIKSTQRYHSQLKSNSVLHKVNTHYLGTPKEYKDVDVFRLPLSLSDSLSVLQTNLYPPEKVRKEIGINYYSFNNNDTITPHTQSDYFYNTSNISSSKKQIKPRILIDNPSNFERFYCMNVSNFSKIVIILLKILLAATPVVKNYTGPINLIAEIVIDQSSPGSSASLVETMQSAIDFLRHKEIISKSTLGILLLIIKHSKFNQHLQFEYLSKIMYESNALVLLYKCLNHESVEKYLFSQNYLNSEEYFNEESLPSSSAASPPPPPIFQPLNCSGSSINSISSGGAGCEGGGANPPPVQLFENYKNLFSTITSLKLIQKVMKHHPSRISSLSASKSANILKKYCSINHPMIRLYSLKVIKNLVPYQTKKWKQINMRIISDIYLEVPIHINDNWLFSHNSAINNNNNNSNNNNNNNNNNSTNNDNGLTDEHEVTLQEKVEEYHRVNYEQWYTNDGLDMCYKNDHSMGIGIFDDLLNSLQLTTEEKQAIENDRLAYIDKDEGSSLIFMNDALEDELLFNKWNIQKPKF
What are the official names of this protein?
Striatin-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the STRIP family.
Protein: RL35_STRP3
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKAGLVSSGDFKRIKAMVTGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RS7_CLOBB
Sequence: MPRKGHIAKRDVLPDPVYNSKVVTKFINSIMEDGKKGVAQKICYEAFELIAQRSGKEALEVFEEAMNNVMPLLEVKARRIGGATYQVPMEVRTERRQTLGIRWMLIAARKRGEKLMCERVAGELLDASNNTGAAVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: Y060_MYCGE
Sequence: MKLSVIIPTYNCASFIEKAINSIVKNRPNDLEIEVLIIDDGSIDNTNKVIKKIQDQINNLTLQYFYKSNGNWGSVINYVRNNKLAKGEWVTVLDSDDIFSKKTISIFQKYAQKQRYDAIIFDYYKCWKKFLWKIPTYARFRKEIKGELKKQTPFCIPLAKFFKNEVFYQLPKLRENVGFQDAIYTMHALQIANNVFHVSKAGGYYFFKRVGNSMSIPWHSSRFDIEVQICKDLIENNAQEIALVHLLRLKFRNLVDDKKIKFTVKRDFCFSGFSWYSRLILSLMYNFWLKRYFNSSE
What are the official names of this protein?
Uncharacterized glycosyltransferase MG060.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: CYAY_BURMA
Sequence: MSDTDYLTRAEAVLAAVERSVDAANDGDADIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFVDGAWRDTRSGDEFFAALTGYATQQAGMPIAFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RS19_DESDA
Sequence: MPRSLKKGPFVDGHLMKKVDTAVANSDRRVLKTWSRRSTILPEMVGLTFAVHNGKKFVPVFVTENMVGHKLGEFSPTRTYHGHAADKKAKAGRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y1717_STRR6
Sequence: MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYCQITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELKDCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNRQLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSLSPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDIIPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLLDTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKKV
What are the official names of this protein?
Uncharacterized RNA methyltransferase spr1717.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: Y1759_STAAE
Sequence: MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRQY
What are the official names of this protein?
UPF0374 protein NWMN_1759.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RNH2_METBF
Sequence: MMIAGIDEAGKGPVIGPMCIGGVKIEESRAHILKVLGVADSKKLTPKKREQLAAQIKKHADGFFVLEVSPSQIDELRKIMTMNEIMVVCFSKVLEQLKPDLLYADAADVNAERFATNIRKQYSKTNPDHAKEIEIISMHQADATYPVVSAASIIAKVRRDELIEELKKEWGLDFGSGYPSDPKTKEFLLNWGKEHSGEFPEIVRQSWQTVENIREELKKTGNKN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB3_ASFM2
Sequence: MEKIFQNVEIKPLLIDFSNPFIKNAAKKLFQLEEQLPLVPVNVVMDFKGINRAAVHGLSRVLQDEIPNYMLDIKPGGYKIEDSTDLFMTEQFIRNRINFIPIYAENESLVFALRSLNNSCEVKTIYTRDLIQVAGPKLKYPIFNPTFEIGFLQPGKSLIIEDIYIKKGIGRKHAAFNLAVKTHFSHLDIEQYPTDKKEYMALSGYKQSSMTSDPRHHRLGLCFPAVPMPRINKAVRTYLKNACRVIIGRIQSIQKIYENFEEPQPELVLFSMDEEKTKAIITIKDETHTIGNLLKTCIYEMIPDISFVGYQCVPHKQEMVLTIIHKASQEDLITLLEKSIQNIIQMFQTLEKNIDELIA
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB3-11 homolog, RPB3-11 homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: ESXD_MYCTU
Sequence: MADTIQVTPQMLRSTANDIQANMEQAMGIAKGYLANQENVMNPATWSGTGVVASHMTATEITNELNKVLTGGTRLAEGLVQAAALMEGHEADSQTAFQALFGASHGS
What are the official names of this protein?
ESAT-6-like protein EsxD.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-2 / type VII secretion system (T7SS).
Protein: B4GT5_DANRE
Sequence: MPTHLRFRRRSFLGLLFLFSLSTSALYFIYSAPGIVNEYLFMVQARGIQIRENVRNMGAQVLEQVVRSAYSINGTDYTYEFNFSETDASPTPFLPEGFTYKPEQVCPEKLPSMKGRLKVNMSEIALDEVEKLLKLNDPGLSVGGHWKPHDCRPRWKVAILVPFRNRHEHLPILFRHLIPALQRQRLQFGFYVIEQAGNEPFNRAMLFNVGFKEAMKDLNWDCVIFHDVDHILENDRNYYGCGEMPRHFAVKLNKYSYMLPYEEFFGGVSGLTVKQFKRINGFPNAFWGWGGEDDDLWNRVQFAGYKVSRPHGELGRYMSIPHHHRGEVQFLGRYKLLRRSKERQSLDGLNNLNYSPLVSRRSLYTNVSVTLSRDLAPVADY
What is the function of this protein?
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (By similarity).  Required for proper patterning of the dorsoventral axis during embryogenesis through the regulation of BMP signaling (PubMed:16672343).  Plays a role in proteoglycan glycosylation that is required for BMP-dependent specification of the dorsoventral axis (PubMed:16672343).
What are the official names of this protein?
Beta-1,4-galactosyltransferase 5, Beta-1,4-GalTase 5, Beta4Gal-T5, b4Gal-T5, Beta-1,4-GalT II, Glucosylceramide beta-1,4-galactosyltransferase, Lactosylceramide synthase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 7 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus. Note=Trans cisternae of Golgi stack.
Protein: AP1M_DIPOM
Sequence: MIHSLFLMNGGGAVFLEKHWRSVVSRSVCAYLLEAQLKAGQPENVAPVLATPHHYLVSTHRHGISFVAVIQAEVPPLFVIEFLHRVAETLQDYFGECSEASIKDNVVIVYELLEEMLDNGFPLATESNILKELIKPPTILRSVVNSITGSSNVGDQLPTGQLSNIPWRRVGVKYTNNEAYFDVTEEIDAIIDKSGSTVFAEIQGVIDACIKLTGMPDLTLSFLNPRLLDDVSFHPCVRFKRWESERVLSFIPPVGNFRLMSYHVNSQNLVAIPVYVKHNINFRDDGSTGWFDITIGPKQTMGKVVENILVIIHMPKVVLNMTLTAAQGNFTFDPVTKVLIWDIGKIILPKLPTLKGLINLQSGEAKPEENPTLNIQFRIQQLAVSGLKVNRLDMYGERYKPFKGVKYVTKAGKFQVRT
What is the function of this protein?
Component of the adapter complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  AP47 is a subunit of the plasma membrane adapter.
What are the official names of this protein?
AP-1 complex subunit mu, Clathrin assembly protein complex 1 mu medium chain homolog, Clathrin coat assembly protein AP47 homolog, Clathrin coat-associated protein AP47 homolog, Golgi adaptor AP-1 47 kDa protein homolog, HA1 47 kDa subunit homolog, Mu-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin- coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: RL7A_HALLT
Sequence: MPVYVDYETPADLAERSLEALEVARDTGTVKKGTNETTKAVERGNADLVIVAEDVSPEEIVMHLPELAEEKGIPVVFVDTQDEVGHAAGLEVGSAAAAVIDAGDADDDVEDIGEKVAELR
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_RICRS
Sequence: MRFSDNLAKILDKYENLGNKLSSGIMGDEFVKASKEYAELEDVVAKIKEYNKAKSELEEANNFKLEVGLDNATLEMIEDEIYTLENSLPKLERAVKIALLPKDDADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAELKGWRFEILAISDTGIGGYKEASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEEVDIKIEDKDLRIDTYRASGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARIYEEERRKKEQARADSRRGQVGSGDRSERIRTYNFPQGRVSDHRIHLTLYKIDEVVKNGQLDEFVEALIADDEAKKLLEI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1480_MYCTU
Sequence: MTESKAPAVVHPPSMLRGDIDDPKLAAALRTLELTVKQKLDGVLHGDHLGLIPGPGSEPGESRLYQPGDDVRRMDWAVTARTTHPHVRQMIADRELETWLVVDMSASLDFGTACCEKRDLAVAAAAAITFLNSGGGNRLGALIANGAAMTRVPARTGRQHQHTMLRTIATMPQAPAGVRGDLAVAIDALRRPERRRGMAVIISDFLGPINWMRPLRAIAARHEVLAIEVLDPRDVELPDVGDVVLQDAESGVVREFSIDPALRDDFARAAAAHRADVARTIRGCGAPLLSLRTDRDWLADIVRFVASRRRGALAGHQ
What are the official names of this protein?
Uncharacterized protein Rv1480.
What is the protein family that this protein belongs to?
To M.avium MAV169.
Protein: GST1C_ANOGA
Sequence: MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKINPQHCIPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRMYFDMGTLYQRFADYYYPQIFAKQPANPENEQKMKDAVGFLNSFLDGHKYVAGDSLTIADLSILATISTYDVAGFDLAKYQHVAAWYENIRKEAPGAAINQAGIEEFKKYFEK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Has DDT dehydrochlorinase activity.
What are the official names of this protein?
Glutathione S-transferase 1, isoform C, AgGst1-alpha, Aggst1-5, DDT-dehydrochlorinase, GST class-theta.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
Protein: CH10_BRECH
Sequence: MLKPLGDRVVIEAISKDEMTASGIVLPDSAKEKPQEGRVIAVGSGRVADNGERIALEVKDGDKVIFSKYAGTEVKVDNKEYLVLRESDILAIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_BURCJ
Sequence: MNSETPAAGPQQAQPPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELEAALADGRADLAVHSLKDVPMALPDGFALAAIMEREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRSRYPHLEVLPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLEARIRALLDVEASPPAAGQGALGIEIAAHRDDVAAWLAPLHDPRTALAVEAERMVSRALGGSCEVPLAAHAVWRAGELYLTGRVSTTDGKRVLTAEECGAVMTVADALALGRAVSDELEAQGALDIVQALLAGSQAAGKGDA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: Y276_BARHE
Sequence: MGIIKFDKVTQVFGDLYVLRNITVQLTERRIAVIGANGSGKSTFVRLINGLQLPSHGFVSVDGLDTKNDAKAIKHKVGFVFQNPDNQIVLPLVEEDLSFGLKNLKLSKEEVKERVDEILQRYDLQNFRNHAVHLLSGGQKQLVAISGVVAMKPDYIIFDEPTTLLDLRNKRLITQVIEELSQTAIVVSHDLEFIRNFDRVLVFDKGEIVVDDIPLVAIKEYIRRMS
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein BH02760.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPD_YERPS
Sequence: MQQLQNVIETAFERRADITPANVDTVTREAITHVIDLLDTGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVMEGAETRYYDKVPMKFAGYDEARFQHEGFRVVPPATVRKGAFIARNTVLMPSYVNIGAFVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFVGARSEVVEGVIVEEGSVISMGVFIGQSTRIYDRETGEVHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTRSKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFUT2_PLAFO
Sequence: MKFIIVLLLFFFFKVIDRVICVTPQKLICLKEDVYLGDFFFFLKRKKYIMYDVNIGEGFNLQKEIFYRLSLVIYNLNKKDKINIYYLVLPPWCYVTHWNIRKGNNLRWEFFFNTDIMKKVIPIIEYEEYEKLYGNYSDIMINSKYILDNYKEKSFLILPFEECNINVNRFKQFCKKCEHKYNVLYSGYCTTINTKQSECYSYNMISNYFITSILENLFLYNITSVLIKQSTNILVPFVNELYQSNLEDILLFNNKLLSYGNNYISNILKTNHYISSHLRYTDFKYISRYNVPPIHIALLKLLYIMFINNCRIIFIASDEKVEIQKVINKDFHQYKKHFYFYNNQNNLHEGEFSIIEQWICTRSYIFIGNIFSRFTMNINWERHLINKGQINQNIDLCSYHINDDNDQDIKNSYKKIVHIFNHKALQKIKNIYDNYSDRDKKYINTICYNFLSHFPNNRSIYRKEYITNT
What is the function of this protein?
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively (By similarity).  O-fucosylates sporozoite proteins CSP and TRAP (By similarity).  O-fucosylation regulates stability and intracellular trafficking of TRAP but not of CSP (PubMed:28916755).  Probably by regulating protein O-fucosylation, may play a role in parasite transmission to the mosquito vector and/or infection of the vertebrate host hepatocytes; however, POFUT2 involvement in transmission/infection is controversial (PubMed:28916755, PubMed:31334132).
What are the official names of this protein?
GDP-fucose protein O-fucosyltransferase 2, Protein O-fucosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 68 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: TADA3_PONAB
Sequence: MSELKDCPLQFHDFKSVDHLKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRRFLKLGRDHELGAPPKHGKPKKQKLEGKAGHGPGPGPGRPKSKNLQPKVQEYEFTDDPIDVPRIPKNDAPNRFWASVEPYCADITSEEVRTLEELLKPPEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAVADKKKGLMGPLTELDTKDVDALPKKSEAQHEQPEDGCPFGALTQRLLQALVEENIISPMEDSPIPDMSGKESGADGASTSPRNQNKPFSVPHTKSLESRIKEELIAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG
What is the function of this protein?
Functions as a component of the PCAF complex.  The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.  The PCAF complex could be considered as the human version of the yeast SAGA complex.  Also known as a coactivator for p53/TP53-dependent transcriptional activation (By similarity).  Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
What are the official names of this protein?
Transcriptional adapter 3, ADA3 homolog, Transcriptional adapter 3-like, ADA3-like protein.
What is the protein family that this protein belongs to?
Belongs to the NGG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHL1_SCHPO
Sequence: MCHSKEVKFKTNFHHPYTPYDIQLEFMRSLYSSISDGKIGIFESPTGTGKSLSLICASLTWLDEHGGVLLEDNEKSNDNKSNTSSKIPDWVLEQDLKIQKDLVKETHARLEQRLEEIRKRNQSRKNQMSNNSTTYHRETKRRNINAEASTSDNCNNSNTSVDPMDEYLVTAEYTMPSTSEQSEDLFNNGYSSKVSELLRKLSPDNEKPPIVQKIYFTSRTHSQLQQLVQEIKKLNNQTFSTPIRVVSLASRKNLCINNEVRKLRPTSALNEKCIELQGSAHKCPFLQDNTQLWDFRDEALAEIMDIEELVELGQRLKVCPYYGTREAVDSAQIVTLPYPLLLQESARNALNLTLKDNICIIDEAHNLIDAICSMHSSSISFRQVCIAETQLQQYFLRFEKRLNGNNRMHIKQLIKVVYNLKSFFLNCLETNTNSKVINVDSLLVSNGADQINLHHLSEYLNVSKLARKVDGYTKYMHSLGTQELESLNDLRSERFSNGNGYEEDPYTPVLMQLESFLLNIANPAPEGKLFYEKQTGDNPYLKYLLLDPSKHVEILTEQCRSVNLAGGTMSPIDDFITLLFSDEQSRILPFSCDHIVPPENITTILVSQGPAGVPFEFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPSFAFLQQAVKVWEMNGITNRLNAKKPLFIESKDFGDNPLDTFEHYKQSVDAGLSGMLFSVIGGRLSEGINFSDKLGRAVMVVGMPFPNSQDVEWQAKVSYVEEKAKEKGINAKQASQEFYENTCMRAVNQSIGRAIRHRDDYASIILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGPAIRQLATFFRAKKMCD
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase chl1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDHI_VERJA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GLMU_XYLFM
Sequence: MPLSLPLHIVILAAGEGKRMKSALPKVLHPIAGKPMLAHVITTARALTPDVIHVVYGHAGNQVRTAFADQTDLHWVEQTQQLGTGHAVKQTMSAIPNAANVLVLYGDVPLIRAETLQRLPRASTPIAVLVTDLANPAGYGHIVRNSEGKVAAIIEDKDADEEQRRIHTVNTGILCAESTALRRWLSKLSNTNMQGEYYLTDIFASATADLTPANMIMVTDPREVEGVNDLWQLTQLERTWQIRAARALCLQGARVADPARLDQRGTIRIGQNVHIDIDVVLEGEIELGDNVVIGPFVRLKNVKLGPGTKVHAHCDLEGVTTTGSALIGPFARLRPGTMLADGVHIGNFVETKNTSIGADSKANHLTYLGDAQIGTKVNIGAGTITCNYDGVNKSITLIGDGAFIGSHSALIAPVSVGAGATLGAGTVLTHDAPAHQLTVARARQTTLDGWQRPKKKT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_CELJU
Sequence: MDSTRLPVIFLMGPTASGKTDLAMRLREHLPVELISVDSTLVYRGMDIGTAKPSPEELAAAPHRLIDIRDPAEPYSVADFLVDAEREISAIHRQGNIPLLVGGTMLYFRALLDGLAQMPAADTSVRAQIEADAAQFGWPYVHQQLAEVDPDVAADIHPNHSQRVSRALEVYRVSGKTMTQLRREQQASGDVRAFEDRYCVRQIAISPRDRAILHQRIEQRFHAMLAQGLVEEVRRLYQRGDLHTDLPAIRAVGYRQVWDYLDDKLHYDEMVARGIIATRQLAKRQFTWLRGWMTNEGARSTSENSQLHWLYTETEQGKPLAKEEIVRCALNFLKPTAI
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: H4_YEAST
Sequence: MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex.  Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.