PharMolix/UniProtQA huggingface dataset:
Protein: DPO4_DEHMB
Sequence: MSIRRVMHVDLDAFFVSVEQAVRPEFKDKPVIVGGKPERRGVVAAASYEARKFGIHSGMPLITAKHLCPQAIFIEGNHQLYREYSEKFMLILSDFSPFLEPMGLDEAYLEVTGFESLHGSIAQMASKIRRRITAELGINASIGIANSKVAAKIATEQAKPNGQCEVPAGEEASFLAPLDIAVMPGIGKKTEQHLKSLGIDTLGKLAALPASFLKSCLGTYAPYLSNAAMGIDNRPVEMPSEAKSISRETTFETDTRNQTFLEAKLSYLSEKITATLRKRGKQTRVVQIKIRFADFTTLTRQKHLGQPASGNREIFQTALSLMNGILDSDRQAVRLLGVGISDFCGPEKQLEIDPAKARLEKLDASLDKIRQKYGFSSVQTGRTYRLKDMF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_SULIL
Sequence: MEELPATAIGLKVNDGIVLASERRLSYGGYVLSKQAKKVHKIGKFLMAGAGIYGDLQTLTRIMNVEIKYYEISTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMNLDIAAQLITKAIKASIERDITSGDGIDLAIMDKKGNYENKFIPY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS45_YEAST
Sequence: MNLFDVADFYINKIVTSQSKLSVANVNEHQRIKVLLLDKNTTPTISLCATQSELLKHEIYLVERIENEQREVSRHLRCLVYVKPTEETLQHLLRELRNPRYGEYQIFFSNIVSKSQLERLAESDDLEAVTKVEEIFQDFFILNQDLFSFDLQPREFLSNKLVWSEGGLTKCTNSLVSVLLSLKIKPDIRYEGASKICERLAKEVSYEIGKNERTFFDFPVMDSTPVLLILDRNTDPITPLLQPWTYQSMINEYIGIKRNIVDLSKVPRIDKDLEKVTLSSKQDAFFRDTMYLNFGELGDKVKQYVTTYKDKTQTNSQINSIEDIKNFIEKYPEFRKLSGNVAKHMAIVGELDRQLKIKNIWEISEIEQNLSAHDANEEDFSDLIKLLQNEAVDKYYKLKLACIYSLNNQTSSDKIRQLVEILSQQLPPEDVNFFHKFKSLFSRQDKMTQSNHDKDDILTELARRFNSRMNSKSNTAENVYMQHIPEISSLLTDLSKNALFRDRFKEIDTQGHRVIGNQQSKDIPQDVILFVIGGVTYEEARLVHDFNGTMNNRMRVVLGGTSILSTKEYMDSIRSAK
What is the function of this protein?
Essential for vacuolar protein sorting.  Function in membrane traffic between the Golgi and the vacuole.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 45.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cycles between the cytoplasmic side of the vacuolar membrane and the cytoplasm.
Protein: XPOT_HUMAN
Sequence: MDEQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEHQVKYKYSELTTVQQQLIRETLISWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWPKFFFDILSVVDLNPRGVDLYLRILMAIDSELVDRDVVHTSEEARRNTLIKDTMREQCIPNLVESWYQILQNYQFTNSEVTCQCLEVVGAYVSWIDLSLIANDRFINMLLGHMSIEVLREEACDCLFEVVNKGMDPVDKMKLVESLCQVLQSAGFFSIDQEEDVDFLARFSKLVNGMGQSLIVSWSKLIKNGDIKNAQEALQAIETKVALMLQLLIHEDDDISSNIIGFCYDYLHILKQLTVLSDQQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLAQVSPELLLASVRRVFSSTLQNWQTTRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKASALQDMMRTLVTSGVSSYQHTSVTLEFFETVVRYEKFFTVEPQHIPCVLMAFLDHRGLRHSSAKVRSRTAYLFSRFVKSLNKQMNPFIEDILNRIQDLLELSPPENGHQSLLSSDDQLFIYETAGVLIVNSEYPAERKQALMRNLLTPLMEKFKILLEKLMLAQDEERQASLADCLNHAVGFASRTSKAFSNKQTVKQCGCSEVYLDCLQTFLPALSCPLQKDILRSGVRTFLHRMIICLEEEVLPFIPSASEHMLKDCEAKDLQEFIPLINQITAKFKIQVSPFLQQMFMPLLHAIFEVLLRPAEENDQSAALEKQMLRRSYFAFLQTVTGSGMSEVIANQGAENVERVLVTVIQGAVEYPDPIAQKTCFIILSKLVELWGGKDGPVGFADFVYKHIVPACFLAPLKQTFDLADAQTVLALSECAVTLKTIHLKRGPECVQYLQQEYLPSLQVAPEIIQEFCQALQQPDAKVFKNYLKVFFQRAKP
What is the function of this protein?
Mediates the nuclear export of aminoacylated tRNAs.  In the nucleus binds to tRNA and to the GTPase Ran in its active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the export receptor.  XPOT then return to the nuclear compartment and mediate another round of transport.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Exportin-T, Exportin(tRNA), tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear, once bound to tRNA and Ran the complex translocates to the cytoplasm. Shuttles between the nucleus and the cytoplasm.
Protein: LRL25_ARATH
Sequence: MINFSLSLTKSMSYSFIWMLFVIHISCVLSADGNHILCSPSFTCGNQRGLLYPFWIAGRKECGHPDFELDCNAGVPELSISSVKFRILGADYDSGIITLARSDNIDDPCLPNSFTTSFNETVLPLASTTDLLTIYYDCNRNVSSFVSTFVKELDCPDDGTDDRRNYYLTRNLTFLPPSLKLEGNSFLLNDFGGSCSRNVSNPASRTALNTLESTPSTDNLKIALEDGFALEVNSDCRTCIDSKGACGFSQTSSRFVCYYRQEPQNPTRNKVILKLFFIVIYVLGIGAASFAMMGVILVVTCLNCLIRRQRKTLNDPRMRTSDDSRQQNLKALIPLKHYSYAQVTSITKSFAEVIGKGGFGTVYRGTLYDGRSVAVKVLKESQGNGEDFINEVASMSQTSHVNIVTLLGFCSEGYKRAIIYEFMENGSLDKFISSKKSSTMDWRELYGIALGVARGLEYLHHGCRTRIVHFDIKPQNVLLDDNLSPKVSDFGLAKLCERKESILSLMDTRGTIGYIAPEVFSRVYGRVSHKSDVYSYGMLVLDIIGARNKTSTEDTTSSTSSMYFPEWIYRDLEKAHNGKSIETAISNEEDEIAKKMTLVGLWCIQPWPLDRPAMNRVVEMMEGNLDALEVPPRPVLQQIPTATLQESSTFSEDISAYTEICSINVA
What are the official names of this protein?
LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.5, Probable receptor-like serine/threonine-protein kinase LRK10L-2.5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: E4PD_ECOLI
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX2_CENLI
Sequence: KEGYLVNHSTGCKYECFKLGDNDYCLRECKQQYGKGAGGYCYAFGCWCNHLYEQAVVWPLPKKTCN
What is the function of this protein?
Beta toxin that binds site-4 of sodium channels (Nav), reduces peak current (observed on Nav1. 6/SCN8A (IC(50)=172 nM), Nav1. 1/SCN1A, Nav1. 4/SCN4A (weak) and Nav1. 5/SCN5A (weak)), shifts the voltage of activation toward more negative potentials (observed on Nav1. 6 and Nav1. 2 (weak)), and induces resurgent currents at negative voltages following brief and strong depolarizations (observed on Nav1. 6, Nav1. 1 (weak), Nav1. 2 (weak), and Nav1. 4 (weak)) (PubMed:22200496).
What are the official names of this protein?
Beta-toxin Cll2, Cll 2, Cll2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCD3_MYCTO
Sequence: MSRITTDQLRHAVLDRGSFVSWDSEPLAVPVADSYARELAAARAATGADESVQTGEGRVFGRRVAVVACEFDFLGGSIGVAAAERITAAVERATAERLPLLASPSSGGTRMQEGTVAFLQMVKIAAAIQLHNQARLPYLVYLRHPTTGGVFASWGSLGHLTVAEPGALIGFLGPRVYELLYGDPFPSGVQTAENLRRHGIIDGVVALDRLRPMLDRALTVLIDAPEPLPAPQTPAPVPDVPTWDSVVASRRPDRPGVRQLLRHGATDRVLLSGTDQGEAATTLLALARFGGQPTVVLGQQRAVGGGGSTVGPAALREARRGMALAAELCLPLVLVIDAAGPALSAAAEQGGLAGQIAHCLAELVTLDTPTVSILLGQGSGGPALAMLPADRVLAALHGWLAPLPPEGASAIVFRDTAHAAELAAAQGIRSADLLKSGIVDTIVPEYPDAADEPIEFALRLSNAIAAEVHALRKIPAPERLATRLQRYRRIGLPRD
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.
What are the official names of this protein?
Probable biotin-dependent acyl-coenzyme A carboxylase beta3 subunit.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: MK13_RAT
Sequence: MSLIRKRGFYKQDINKTAWELPKTYLAPAHVGSGAYGAVCSAIDKRTGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMHHENVIGLLDVYTPATSVRNFQDFYLVMPFMQTDLQKIMGMEFSEEKVQYLVYQMLKGLKYIHSAGIVHRDLKPGNLAVNEDCELKILDFGLARHTDAEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLKDKAAKSYIQSLPQSPKKDFTQLFPRASPQAVDLLDKMLELDVDKRLTAAQALAHPLFEPLRDPEEETEAQQPFDDALERENLSVDEWKQHIYKEIANFSPIARKDSRRRSGMKLQ
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2.  Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.  MAPK13 is one of the less studied p38 MAPK isoforms.  Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets.  Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.  Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1.  Mediates UV irradiation induced up-regulation of the gene expression of CXCL14.  Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development.  Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway.  MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells.
What are the official names of this protein?
Mitogen-activated protein kinase 13, MAP kinase 13, MAPK 13, Mitogen-activated protein kinase p38 delta, MAP kinase p38 delta, Stress-activated protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: Y883_MYCTO
Sequence: MRELKVVGLDADGKNIICQGAIPSEQFKLPVDDRLRAALRDDSVQPEQAQLDIEVTNVLSPKEIQARIRAGASVEQVAAASGSDIARIRRFAHPVLLERSRAAELATAAHPVLADGPAVLTMQETVAAALVARGLNPDSLTWDAWRNEDSRWTVQLAWKAGRSDNLAHFRFTPGAHGGTATAIDDTAHELINPTFNRPLRPLAPVAHLDFDEPEPAQPTLTVPSAQPVSNRRGKPAIPAWEDVLLGVRSGGRR
What are the official names of this protein?
Uncharacterized protein MT0906.
Protein: RS11_BORBU
Sequence: MSAKLSTNSKKKIKRNIGEGNVYIQATFNNTIVTVSDIKGNALAWASAGGMGFKGAKKSTPYAAQITAESALNKVRDFGINYVHVYIKGPGIGRESAIRAIGSIGMTVKSISDITPIPHNGCRPKKTRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DEOC_CORDI
Sequence: MTTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATVVGFPSGAVKPEIKAAEAARTVADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPGILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPAGGASVHAVEIMHATVGGRLGIKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_ORYSJ
Sequence: MNIIPCSIKTLKGLYDISGVEVGQHFYWQIGGFQIHAQVLITSWVVITILLGSVIIAVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSAAYFYAGLSKKGLSYFEKYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL5_ROSCS
Sequence: MVPRLKEKYQTEVVPALMQEFQYRSVMQAPRLEKIVLNIGLGEAIQNSKALDAATSDLAAIAGQKPVITRARKSIAAFKVRQGMPIGVMVTLRGPRMWSFFDRLVNLVLPRLRDFRGVSRRSFDGRGNYSLGLREQIVFPEIDYDKVDKLRGLEVVIVTTAPDDEQGYALLKRLGMPFRD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: BGAL_ECO57
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTNRPSQQLRSLNGEWQFVWFPAPEAVPESWLECDLPDADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLLSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATLFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLGLNVENPKLWSAEIPNIYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTSATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDLVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGRTIEVTSEYLFRHSDNELLHWTVALDGKPLASGEVPLDVAPQGKQVIELPELPRLESTGQLWLTVHVVQPNATAWSEAGHISAWQQWRLAENLSVTLPSAPHAIPQLTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTVHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: EFHD1_BOVIN
Sequence: MASEELASKLQRRLQWEEGDSGLQPAPGAAPDPEPQPQPPAWAPTARADAELSAQLNRRLDINEGAARPRRCKVFHPYSEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKDFFEAKVQALSCASKFEAELKAEQDERKREEEKRKVRQAAFRELKAAFSA
What is the function of this protein?
Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (By similarity).  May play a role in neuronal differentiation (By similarity).
What are the official names of this protein?
EF-hand domain-containing protein D1, EF-hand domain-containing protein 1, Swiprosin-2.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: NINB_LAMBD
Sequence: MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLDQNRKLWACLGDVSRQVEWHGRWLDAESWKCVFTAALKQQDVVPNLAGNGFVVIGQSTSRMRVGEFAELLELIQAFGTERGVKWSDEARLALEWKARWGDRAA
What are the official names of this protein?
Protein ninB.
What is the protein family that this protein belongs to?
Belongs to the ninB family.
Protein: AADR_RHOPA
Sequence: MPHLAYPTTTCEGFRCETHCAVRGLAICGELGPADHEEFERLAQHVRYGPKEALFSEDEVADSVYSLIEGIARLYKLLPDGRRQIIGFALPGDFLGMAPGNRYSFSADSIGGVTVCKFFRGPFLRFIENRPQMLLRMNDFATRELSLAQDQMLLLGRRSAEEKVAAFLVGWRDRLARLEGVTKTVSLPMGRQDIADFLGLTIETVSRTFTKLEREKLIVIVPDGVRVLDPKRFDALAAA
What is the function of this protein?
Transcriptional activator of anaerobic gene expression.  For aromatic acid degradation.  Also required for the anaerobic degradation of benzoate.
What are the official names of this protein?
Transcriptional activatory protein AadR, Anaerobic aromatic degradation regulator.
Protein: AROA_BORPA
Sequence: MSGLAYLDLPAARLARGEVALPGSKSISNRVLLLAALAEGSTEITGLLDSDDTRVMLAALRQLGVSVGEVADGCVTIEGVARFPIEQAELFLGNAGTAFRPLTAALALMGGDYRLSGVPRMHERPIGDLVDALRQFGAGIEYLGQAGYPPLRIGGGSIRVDGPVRVEGSVSSQFLTALLMAAPVLARRSGQDITIEVVGELISKPYIEITLNLMARFGVSVRRDGWRAFTIARDAAYRGPGRMAIEGDASTASYFLALGAIGGGPVRVTGVGEDSIQGDVAFAATLAAMGADVRYGPGWIETRGVRVAEGGRLKAFDADFNLIPDAAMTAATLALYADGPCRLRNIGSWRVKETDRIHAMHTELEKLGAGVQSGADWLEVAPPAPGGWRDAHIGTWDDHRMAMCFSLAAFGPAAVRILDPGCVSKTFPDYFDVYAGLLAARD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_SALPC
Sequence: MKKTGYFLLAVIVIVAAAGVGYWKFSGNPDALREIVLEQCLPDQLQHQNPAPCAEVKPRAGYVVFKDRHGPLQYLLMPTYRINGTESPLLLEPATPNFFWLAWQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCIRPDVREQLDNDLTRISTRWLPLPGGLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDHMGRYALAVVRQSDDSFVLLATERNLLTFNRASAEEIQDHSCAILSSR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CLSA_CITK8
Sequence: MTTFYTVVSWLVILGYWILIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVASSLFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQVAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDAGFGGDLAAVQDDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACEK_ECOL6
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPLPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRFV
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRK_BACP2
Sequence: MKKAYLTVVSNREIADHIYEMTLKGDLVDSFQTAGQFLHIKVSESMTPLLRRPISIANIHAEKQEATIIYRAEGEGTKLLSQKRDGESIDVLGPLGNGYDPSVVQSGQTALLVGGGIGVPPLYELSKRLTKKGVIVKHVLGFQSKKDVFYEEKFQALGDTFIATVDGTYGAKGFVTNVIEENDLSFDVMLSCGPTPMLKALKDSYPDKPVYISMEERMGCGIGACFACVCHTDQHEKAYVKVCLDGPVFKAEEVALSC
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: Y2348_DICDI
Sequence: MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0272348.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDX2_DICDI
Sequence: MEELIEENNIKIGVLALQGGFKEHVEMVKSIKHCFSECENKYKYSIIVQEVKSVSDIKKLNPHGIILPGGESTSMAIIASSNNDGENIFTFLKEYIKQGNFIWGTCAGSIMLSNNVDGQKVGGQSLIGGLDVLISRNYFGRQIDSFETKINLNLKFSKNNNNSILLENFEAIFIRAPAILDVIDKENVEIIGEYIVTKKDGTKEKVITAVKQNNIIASVFHPELTNDNRFHQYFVQLVLNNHLIKIKI
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of pdx1.
What are the official names of this protein?
Probable pyridoxal 5'-phosphate synthase subunit pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.