PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_BACFN
Sequence: MKEIIYIFIGGGMGSVTRYLTQIAVNERLSPALFPFPWGTFAVNIIGSLLIGFFYSFSERFNLSFELRLFLTVGFCGGFTTFSTLANDSLSLLKGGFYGIFTFYVFISILLGLLAVLAGGYLGEQFK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ODPA_BACSU
Sequence: MAAKTKKAIVDSKKQFDAIKKQFETFQILNEKGEVVNEAAMPDLTDDQLKELMRRMVFTRVLDQRSISLNRQGRLGFYAPTAGQEASQIATHFALEKEDFVLPGYRDVPQLIWHGLPLYQAFLFSRGHFRGNQMPDDVNALSPQIIIGAQYIQTAGVALGLKKRGKKAVAITYTGDGGASQGDFYEGINFAGAYKAPAIFVVQNNRYAISTPVEKQSAAETIAQKAVAAGIVGVQVDGMDPLAVYAATAEARERAINGEGPTLIETLTFRYGPHTMAGDDPTKYRTKEIENEWEQKDPLVRFRAFLENKGLWSEEEEAKVIEDAKEEIKQAIKKADAEPKQKVTDLMKIMYEKMPHNLEEQFEIYTQKESK
What is the function of this protein?
The B. subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, S complex, 42 kDa subunit, Vegetative protein 220, VEG220.
Protein: OHRL_MYCGE
Sequence: MALIYKTVAQTETGREGSVKTLDGFQTKLSFPKPDLSVQTENNPEQLFASAYASCFSQAVIVVMQQHQFSFSKKPVVSVKVELHQENGLFHIKAGVELTTNSNDQEVGKKLIQKAHEMCPFSRLIRNENFLGLTLNGIKL
What are the official names of this protein?
Organic hydroperoxide resistance protein-like.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: PSBI_PROM1
Sequence: MLALKISVYTVVFFFVGIFLFGFLASDPTRTPNRKDLESPQD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TLS1_HUMAN
Sequence: MPVVRKIFRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY
What is the function of this protein?
Plays a role in pre-mRNA splicing by promoting usage of the upstream 3'-splice site at alternative NAGNAG splice sites; these are sites featuring alternative acceptor motifs separated by only a few nucleotides (PubMed:35241646).  May also modulate exon inclusion events (PubMed:35241646).  Plays a role in spliceosomal remodeling by displacing WBP4 from SNRNP200 and may act to inhibit SNRNP200 helicase activity (PubMed:35241646).  Binds U5 snRNA (PubMed:35241646).  Required for proper chromosome segregation (PubMed:35167828).  Not required for splicing of shelterin components (PubMed:35167828).
What are the official names of this protein?
Splicing factor C9orf78, Hepatocellular carcinoma-associated antigen 59.
What is the protein family that this protein belongs to?
Belongs to the TLS1 family.
Protein: BIOD_ACTSZ
Sequence: MRTFFVTGTDTGVGKTICSRAIIQALQEMDTQIVGFKPIASGQDEPVYADSLDDPKNDYGDEDNRDVLILQNSTKENVSYRDINSYTFLQTVPMITAEKGRIKLEKVDRDLARLAATYDVVAVEGSFGWLSPMNERFTFADWVVKHNMPVIVAVGIKEGCINHALLTVQSVEKMGLPVLGWIANRINPGLSHYAEIIDVLSSKIAAPLLGCIPYIHKPETQDVGKFLTNTEQLRHIQTLLAK
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRM1_MOUSE
Sequence: MTTSGALFPSLVPGSRGSSTKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGTVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNECLNNPPMPGSLGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPASSSSSSSRSQSAAVTPSSSTSSARATPAPSAPAAASATSPSPAPSSGNGTSTAASPTQPIQLSDLQSILATMNVPAGPGGSQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKSDPKEGDTKDKKDEEEDMSLD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins (PubMed:18497827).  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required (PubMed:18497827).  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair (PubMed:18497827).  Within the complex, functions as a proteasomal ubiquitin receptor (PubMed:18497827).  Engages and thus activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation (By similarity).  UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex (By similarity).
What are the official names of this protein?
Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog.
What is the protein family that this protein belongs to?
Belongs to the ADRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HNM1_YEAST
Sequence: MSIRNDNASGGYMQPDQSSNASMHKRDLRVEEEIKPLDDMDSKGAVAADGEVHLRKSFSLWSILGVGFGLTNSWFGISTSMVAGISSGGPMMIVYGIIIVALISICIGTSLGELSSAYPHAGGQFWWSLKLAPPKYKRFAAYMCGSFAYAGSVFTSASTTLSVATEVVGMYALTHPEFIPKRWHIFVCFELLHLFLMFFNCYGKSLPIISSSSLYISLLSFFTITITVLACSHGKFNDAKFVFATFNNETGWKNGGIAFIVGLINPAWSFSCLDCATHMAFEVEKPERVIPIAIMGTVAIGFVTSFCYVIAMFFSIQDLDAVLSSTTGAPILDIYNQALGNKSGAIFLGCLILFTSFGCVIACHTWQARLCWSFARDNGLPLSRLWSQVNPHTGVPLNAHLMSCAWITLIGLLYLASSTAFQSLITGCIAFLLLSYIIPVICLLAKKRNIAHGPFWLGKFGFFSNIVLLGWTVFSVVFFSFPPVLPVTKDNMNYVCVVIVGYTAYSILYWKYKGKKEFHALEESENEQAEYSNNFDTIEDSREFSVAASDVELENEHVPWGKK
What is the function of this protein?
Sole choline transporter in yeast.
What are the official names of this protein?
Choline transport protein.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2.A.3.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ASSY_BRUC2
Sequence: MSKWKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIFIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIDIAKKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTQLLEFAEQHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPSQEAPEYVHMRTISPETAPDKATIIKIGFEKGDAVSINGERLSPATLLAKLNDYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDHSQRHVEGEVTLKLYKGNVMVIGRESAKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARDRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E322_ADECR
Sequence: MRFCFFFCFTASIFCTTGNSSDIVFCCAHTPCLLHLEVDQETSVTWIDSNTGQIPLCLSNGTCHISEKGLHFSANFSKDGLYIAIINETNYHAAEHYYLVYIYENCHQMPYDSPRHTGHKGTSFNWSMGLWLVKCSHNKTFFLPFVLDSAKSAPIIMTETAITIYISMIFLIVSLLTFLNVLITLNNKYKHYGV
What are the official names of this protein?
Early E3 22.1 kDa glycoprotein.
Protein: SLAA_PROFL
Sequence: MERLIFVSFGLLVVILSLSGTGADFDCIPGWSAYDRYCYQAFSKPKNWEDAESFCEEGVKTSHLVSIESSGEGDFVAQLVAEKIKTSFQYVWIGLRIQNKEQQCRSEWSDASSVNYENLVKQFSKKCYALKKGTELRTWFNVYCGTENPFVCKYTPEC
What is the function of this protein?
Strong platelet aggregation inhibitor.  Binds specifically to platelet glycoprotein Ibalpha (GP1BA) with high affinity and inhibits vWF-dependent platelet aggregation (PubMed:7599152).  Has also been observed to induce small agglutinates in washed platelets by binding to GPIb (PubMed:10688335).
What are the official names of this protein?
Snaclec flavocetin-A subunit alpha, FL-A subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: NS1_I88A4
Sequence: MDSNTMSSFQVDCFLWHVRKRIADQELGDAPFLDRLRRDQKSLRGRGNTLGLDIETATRAGKQIVERILEEESDEAPKMTIASVPASRYLTDMTLEEMSREWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPSLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: PUR4_DICDI
Sequence: MTIQQFYRKPAISEYEIKLLKNNLKKQHNIDIESIETEYCFNVQYPDNHKLNESEQSTLVWLLSETFEPKNFSIDKSFLKTTTTTTENEIIIEVGPRMNFTTTYSSNATSICKSCNLSIIDRIERSRRYLVKSVSKLSEKQIDQFLELIHDRMTECLYPTPIKSFDTGIIPKAVVYIPVVEEGRAALERVNKEMGLAFDEQDLALYTDLFQNQLKRNPSDVECFDIGQSNSEHSRHWFFNGKLIVDGNMSDKTLFQIVKNTLKANPQNSLIAFSDNSSSIKGFKTKVLIPKSQIEASEYLEGEREQPIIFTAETHNFPTGIAPFEGAETGTGGRLRDTHATGRGSLVVAGTVGYCVGNLNIPGYELPWENKEYNYPDNMANPLKIEIEASNGASDYGNKFGEPVIIGFTRSYGNTLPNGERREWIKPIMFSGGIGFMDERHLKKEQPEIGMVVVKAGGPAYRIGMGGGSASSMVGGDNKHELDFSAVQRGDAEMGQKLNRIVRSCVESEIHGGCNPIVSVHDQGAGGAGNVLKEIVDPLGAKIYLDRIISGDPTLSAMEIWGAEYQENDALLIKAEHKDYLKKVSERERLPIAFVGDVTGDGIAQLITKDGETPVNLPLDKVLQKMPPKTFVLDHVEKQLKPFTLPKELLVGDHQTCFNECLNRVLRLLSVGSKRFLINKVDRAVTGLVARQQCVGPLHTPVSNVAVISSGYFGKSGAATSIGEQPIKGFISAKSMAYLTVGEALTNLMWASITDLGDVKCSGNWMWAAKLKGEGVELYDAAIEMHDVMVELGIAIDGGKDSLSMAAKAPKSDGSQELVKAPGALVVSTYVPCDDITLTVTPDLKLSSKDDSVILYLDLGCANNFIGGSALTQVFNQVGNDEPHHNTPLLKNTFMAIQKLVKQQLISAGHDRSDGGLITTLIEMSLSGNRGLEINLPDTHNSDQSPLSIIKLLFSEELGAVLEIKKSNQQIVLDILKQFNVPTQVIGNTSCNNNNNNNNNGSDEDLFIVKVGDKLIYNIKLSQLSKQWEETSYQLELLQANPTFVESEMKNLLKRATGKGKGPNYNMTYKISPISKELALLANKAPKVAVIREEGSNGDREMAAAFHFAGFQAFDVTMSDLLNGNIQLDERFKGVAFVGGFSYGDVMDSAKGWAGSIRFNQQVSKQFDHFYGRNDTFSLGLCNGCQLMALLGWVPYRGIEQTHQPRFIHNASGRFESRWVNVKIMPSPALLLKGMEGSVLGVWSQHGEGRFWSEDQSIVNDIKANNLSPIRYVDDDGEITESYPFNPSGTQEGFASLCSKDGRHLAIMPHPERSFLSWQWPFMPENIKQNVGGLDQPSPWIKIFQNAKSFCDSLN
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (By similarity).
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT, Formylglycinamide ribotide amidotransferase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_HAES1
Sequence: MCRGNLYIISAPSGAGKSSLISALLERDKNDSMTVSISHTTRSPRPGEIDGVHYHFVSHEKFEQLILENSFLEYAKVFGGNYYGTSLLNIEKNLAAGIDVFLDIDWQGARQIREKRPDVKSIFILPPSISALEKRLIGRGQDSQDIIAKRMEKAADEISHYDEYDYVIINADFDQALVDLEHILRAERLTVNYQKTQNAALIHQLLVK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIGR1_ORYSJ
Sequence: MDLHQLLKYRLTGANVVYEIPTENNLQNSPWQANPLKYEFSDSPYTPLSSQFECDNLSALTNTPDNQSSTETISAQPISPLEADSSYRQAGILLQENIQVGADPLYATSRHNMQHALREIETVLMAPDTDDATTSTKHEFEEIKPAQLVRQRSRTWSHESRQPLPGVGRSQFASGGYPTASYEFRPEKRQRELREDPQIIVKQLLTRCAEALSEDRTEEFHKLVQEARGVVSINGEPIQRLGAYLLEGLVARHGNSGTNIYRALKCREPESKELLSYMRILYNICPYFKFGYMAANGAIAEALRTENNIHIIDFQIAQGTQWITLIQALAARPGGPPRVRITGIDDPVSEYARGEGLDIVGKMLKSMSEEFKIPLEFTPLSVYATQVTKEMLEIRPGEALSVNFTLQLHHTPDESVDVNNPRDGLLRMVKGLSPKVTTLVEQESHTNTTPFLMRFGETMEYYSAMFESIDANLPRDNKERISVEQHCLAKDIVNIIACEGKDRVERHELLGKWKSRLTMAGFRPYPLSSYVNSVIRKLLACYSDKYTLDEKDGAMLLGWRSRKLISASAWH
What is the function of this protein?
May play a regulatory role in the early step of oligosaccharide elicitor response, downstream of the membrane-associated high-affinity chitin-binding protein.
What are the official names of this protein?
Chitin-inducible gibberellin-responsive protein 1.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSGF_ECOL6
Sequence: MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNSAQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIVDIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF
What is the function of this protein?
May be involved in the biogenesis of curli organelles.
What are the official names of this protein?
Curli production assembly/transport component CsgF.
Protein: LUXO_VIBC3
Sequence: MQEFSLSTLLEMTVGLASGANNEERFHRLLDAVRKAVICDCVVLMSLHNDTLTPLAMQGLTRDTLGRRFVVSEHPRLAQICSADLPVRFAADCPLPDPFDGLLLDSEDDLPMHSCMGLPLHFGEQLLGILTLDSLKPDAFDHLSPRSLEILAAIAAATLKMTLTFSELENQAKQTQLRLEELNQEAWSRDSVEIIGNSGPMLAMKADIDVVAPSQFNILIHGETGVGKELVARTIHQRSNRKRQPLVYVNCAAIPENLLESELFGHVKGAFTGADRARMGKFALADGGTLFLDEIGELPLSAQSKILRALQNHEIQPVGQDRVQTVDVRILAATNRDLKKEVEAGRFRADLYHRLSVYPIYVPPLRERKGDLSLLAGYFVEQARRKLGITQLKLHGDVLSQLIQYPWPGNVRELEHVINRAALKAKARQRGRPVTTLKVEDLGELQGPRAAMVEPTAQDEPMLGEWIGELGLRDATDEFQRHLISETLTQADFNWAEAARRLQTDRANLTRLAKRLGITVSRSHSIERSR
What is the function of this protein?
Involved in the regulation of different processes depending on the cell density.  Acts together with sigma-54 to repress, perhaps indirectly, some genes.
What are the official names of this protein?
Regulatory protein LuxO.
Protein: SYK_BACFR
Sequence: MNILELSEQEIIRRNSLNELRAMGIEPYPAAEYVTNAFSTDIKAEFKDDETPRQVSVAGRMMSRRIMGKASFIELQDSKGRIQVYITRDDICPGEDKEMYNTVFKRLLDLGDFIGIEGFVFRTQMGEISIHAQKLTVLAKSIKPLPIVKYKDGVTYDSFEDPELRYRQRYVDLAVNEGVKDIFIKRSKVYSSMREYFNSKGYMEVETPILQAIAGGAAARPFMTHHNALDIPLYMRIASELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMEIYVAYKDYNWMMEFTEKMIEKICLDVNGTTEVKVGDNIINFKAPYKRVTMLGAIKEHTGYDLTGMNEEQIREVCKKLNMEIDDTMGKGKLIDEIFGEFCEGTYIQPTFITDYPIEMSPLTKKHRDNPELTERFELMVNGKELCNAYSELNDPIDQLERFEDQMKLSEKGDDEAMIIDKDFVRALEYGMPPTSGMGIGMDRLTMLMTGQSTIQEVLFFPQMRPEKVVPKDSASKFMELGITEEWVPVIQKAGYNQVADMKEVNPQKFHQDICGINKKYKLELTNPSVNDVAEWIQKIK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGKH_SCEFU
Sequence: AKKSVGDLTKADLEGKRVFVRADLNVPLDKEQKXTD
What are the official names of this protein?
Phosphoglycerate kinase, chloroplastic, Period clock protein.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1298_RICBR
Sequence: MKKLLLASIIGLASTTSFASGSTTPVISSSDSEIKLEGFYLFESGFSNQNRLGEFENLSDNRKKTAFYTEAAFAATITKTINDVIGGVKIVLQPTTRSKTSTSYNGSHIFIETSYGKVELGSPYDAGNKLRITGGQVAAGSGGYLRYINVGSKYMQYEKLKPDFDTSPSFYIESFSNNFDEFNVKAEAARKISFYTPKMKGFQAGISYTPDSANTGGNKNINNVVFDDSITGITNVRTGIKRNIVENDEIITINQNVTDSISGGLTYEHALGEDADLKLSVTGEYGKPARLAVRSKVIDKTYTVLDTYKLSNLKAYNLGAVFTYGNFSCGASYGSLGKSLTTPQYHKNGRNTYYYNGAIAYGQGPIKTSLSYFKSSRYKNTVDTITVATEYKIMPGLLPYAEISHFQAKGKPVYYPEAPNKKTKGTVGLIGTKLKF
What are the official names of this protein?
Uncharacterized protein RBE_1298.
Protein: BIOB_STAAR
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSREIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL2_MYCTA
Sequence: MAIRKYKPTTPGRRGASVSDFAEITRSTPEKSLVRPLHGRGGRNAHGRITTRHKGGGHKRAYRMIDFRRNDKDGVNAKVAHIEYDPNRTARIALLHYLDGEKRYIIAPNGLSQGDVVESGANADIKPGNNLPLRNIPAGTLIHAVELRPGGGAKLARSAGSSIQLLGKEASYASLRMPSGEIRRVDVRCRATVGEVGNAEQANINWGKAGRMRWKGKRPSVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRNANKSSNKFIVRRRRTGKKHSR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PHCA_TOLSC
Sequence: VKTPITEAIAAADTQG
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: EXOC8_HUMAN
Sequence: MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPGQYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIRLGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLTFIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSNFEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDYSLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPESTTSVV
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 8, Exocyst complex 84 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Cell projection. Note=Perinuclear in undifferentiated PC12 cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). Binds lipids with phosphatidylinositol 3,4,5-trisphosphate groups (By similarity). Localizes at the leading edge of migrating cells (By similarity).
Protein: NQO2_PONAB
Sequence: MAGKKVLIVYAHQEPRSFNGSLKNVAVDELSRQGCTVTVSDLYAMNFEPRATKKDITGALSNPEVFHYGVETHEAYKQRSLASDITDEQKKVQEADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDFRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWYFRQ
What is the function of this protein?
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
What are the official names of this protein?
Ribosyldihydronicotinamide dehydrogenase [quinone], NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_UREP2
Sequence: MKTNYEFRPQYLKDFIGKEQLKNNLKVYLTASKRLENSFDHTLLHGLSGTGKTTLALIIANEMNVNCHITQGNLLNKPIDIINLLSLIKENDVVFIDEIHACGLGAFETLYSVLEDFCIDINIGKDFNSKMTRLKIPHFTLIGATTIFGKIPKSLEERFGHIFHLNEYEPSEISAIILKNNQMHFQIDLNEEEIDLIANNAKGIPRLANRLLKRVVDFKINGFNDIKNIFKKIQIYEFGLDEQDINYLNVLYRQDNEIGLKSIAQILRLDQYTIETKIEPYLIQHHFINKNLRGRKITIEGIDFLKNNQLIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YKD0_YEAST
Sequence: MFLCYCCCCYCFYYCIIVLLLYYYYYYYYYYYYGMSSIIFFLKIKKKIVQIYIFIYYSIWFFFFKCRRWLCFVYNWLVCTDGSCWTLIIGLYTGSHIWALTHCKHSSKSRGTLTVSPGAPPGTCSCSIRAVPSSSACKITAVARRAEVLVMVSRPGSNPGLESPSLSGDNSASWSTAAEIILSVMVVARDSTAPKPIPGKE
What are the official names of this protein?
Putative uncharacterized protein YKL030W.