PharMolix/UniProtQA huggingface dataset:
Protein: NUOI_YERPA
Sequence: MTLKELVVGFGTQVRSLWMIGLHAFHKRETLMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAEQKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKQKGEAENEAKPIDVKGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ADRB2_MERUN
Sequence: LACAGLVMGLAVVPFGASHILMNMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYIAITAPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATNKEAITCYTNETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNVVHAIKENLIPKEVYILLNWLGYVNSAFNPLI
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity).
What are the official names of this protein?
Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane. Activated receptors are internalized into endosomes prior to their degradation in lysosomes. Activated receptors are also detected within the Golgi apparatus.
Protein: CYSI_MANSM
Sequence: MSDKKQKGLEWQDNPLSDNERLKEESNHLRGTILDDLEDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERQEEKLEPRKFMLLRCRLPGGIIKPEQWIEIDKFARDNNYYQSIRLTNRQTFQYHGVPKTKLQDMHRLLHKLGLDSIATASDMNRNVLCSSNPVESELHQEAYEWAKKISEHLLPRTNGYLDVWISGKKVQSSDSFLGQEDEPILGNRYLPRKYKTAVVLPPLNDVDLYSNDMNFVGIKDEKTGKLAGFNVLVGGGLSFEHGNTKTYPNIALELGYVPVEDTLKAAESIVTTQRDFGNRADRKNARLRYTIQNMTLEGFREEVERRMGRRFEAIRPFEFTERGDRIGWVKGIDKKWHLTCFIESGRLVDKPDLPLMTGMLELAKVHKGDFRITANQNIIIANVAEEDKRQIEDIARQYGLIRKITKLRENAMSCVSFPTCPLAMAESERVLPEFIDELDKIMAKHHVEQDYIVTRITGCPNGCGRAMLAEIGLVGKAVGRYNLHLGGNIAGTRIPRLYKENITLDEILSELDGLIARWATERDQGEGFGDFVLRVGIIKPVVNPVVDFWDENLIPTVAV
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: CINAL_KORVE
Sequence: MIAEIVAIGSELLTPFRQDTNSLYLTQRLNEMGVEVAFKNIVGDSRANLASVARTAIARSHIVLFMGGLGPTEDDLTREAVADALGLRLKRNPDLVAELYKRFASRRVTMPDNNMRQADVIAGAEIIQNDNGSAPGQFIEGEQDGQPRYIFLLPGPPHELKAMWNEKCHHTLRDRLPRAYIATRELRISSLGESTVDARVAPIYTKYKNVDTTILAKPGEVSLHLKSRAATMEQAQAAVDQLAAELEDELDDAVFSTNGESLEQIVGYYLQMRSGTISVAESCTGGLLAERLTNVSGSSRYFIGGVVVYSNQMKTLLADVPPLMIEEHGAVSRQVAVALAENFREITNSTIGVGITGIAGPTGGTEDKPVGLVYIAVADELGTDVVERRFPGDRERIRWWSSQVALDMVRKKLI
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: M2_I77AB
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQNAVDADDSHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RL332_STRPD
Sequence: MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MB43_VZVO
Sequence: MAVNGERAVHDENLGVLDRELIRAQSIQGCVGNPQECNSCAITSASRLFLVGLQASVITSGLILQYHVCEAAVNATIMGLIVVSGLWPTSVKFLRTLAKLGRCLQTVVVLGFAVLWAVGCPISRDLPFVELLGISISAITGTVAAVHIHYYNFVTTFNGPHIYFYVMMLGTGLGGLLTVILYMYVSKYEVLIGLCISIVTLVSIVDAATDLQDTCIYRKNRHKQLNTYTDLGFAVVYTQNDRGRVCDHRESSRTLKRVFKGIRIMSVIPPVLYIVTPLMWAISHIIKLNHFIKLTQVTLAVSIGGHIIAFGLQGFAVLYQEKKNLWVIVLYTTTSVTGIAVTFAGISWGAIIILTSTVAAGLTCIQMMRLSVKPIDCFMASHITKVYHVCVYIIINLCYLCGTYVS
What are the official names of this protein?
Membrane protein UL43 homolog, Membrane protein ORF15.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL43 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNME_LEPBL
Sequence: MNDTIAAVSTASGPGAIGIIRMSGPGALSISSSFLFSKNGFLSPSDIQPRIAIQCVFQIGDRKIDQILFFYFKTPNSYTGEDLCEFHFHGNPILLREALDAIFRAGARPAKQGEFSRRAFLNGKLDLTGVEAIGRLISARSRFELELAQKNVFGEVSRLTSNLRSQLISLKAECEAEIDFSTEDLTYESLEERKVRIEGVKTFCQTVIAKSNSAEKVIQQLRIVLYGEPNTGKSSLMNVLLGKDRSIISEIPGTTRDYISEEILLEGIPVRLVDTAGVRETEDHIERLGIERSEKEFQSADIRLFLIDVSKKEEWKKFIAKAKGRLEGSILVANKIDIRDSSWNPNLFSDVKDLIICEISCKTKEGIPILLDEIQKKAATMGHVEDYVLLEERQRYHFETIVRCLDKTLRLIEEGAPAEIYIQEMNYALSEIGEVNGRVDTEEVLGRIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_BORT9
Sequence: MKSGFVSIIGRPSTGKSTLLNSICEHQISIISSIPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKQFNIALMHNVHSAIKETELILYVIDIQDKPGIEENEILTIISKSKINFLVVINKIDIQKTKEREIMIFLEEKGIKKDNIIKISAEQKINIEEIKDKIYENLQEGPLYYPEEYYTDQEMNLRTSEIIRGVTIKKLKEELPYSLYIEIEILEDRKNKLFIKANIIVAVESQKGIIVGKGGKGIKTIGEEARKIISEIFEKKCDLFLQVKLRKNWNKNPKLIKNLIN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: NU2C_RIPO1
Sequence: MDFSSTIASQLNAGTILPEGIVIITLVGVLVGDLIFGRSSKSWLPYMAIIGLLASIVALYLAWDSPHPIGFLNSFNSDNLSIVFRAIIALSTAVTILMSIRYVEQTGTSLAEFIAIMLTATLGGMFLCGANELVMIFISLEMLSISSYLMTGYMKRDPRSNEAALKYLLIGASSSAIFLYGVSLLYGLSAGETALDAIATKIAAANGGESLGLAIALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFASVGEEWHFVFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVAGTDAGYSSMVFYLLVYLFMNLGAFACIILFSLRTGTDKISEYAGLYQKDPLLTLALSICLLSLGGIPPLAGFFGKIYLFWAGWQAELYGLVILGLVTSVVSIYYYIRVVKMMVVKEPQEMSDAVKNYPQIRWNLPGMRPLQVGIVLTLIATSLAGILSNPLFTLANDSVTSTPILQSAIINTRISQVPTESK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL28_EXISA
Sequence: MARKCYVTGKSPKSGNNRSHALNKTKRTWGVNVQKVRILVDGKPKRVWVSARALKSGLVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ERFK_ECOLI
Sequence: MRRVNILCSFALLFASHTSLAVTYPLPPEGSRLVGQSFTVTVPDHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKSGSQLTIPQQLILPDTVRKGIVVNVAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYAKRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKYLFDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTPSLRAFINGQEVDVNRANAALQRRSGMPVQISSGSRQMF
What is the function of this protein?
Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp.
What are the official names of this protein?
Probable L,D-transpeptidase ErfK/SrfK.
What is the protein family that this protein belongs to?
Belongs to the YkuD family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FST_PIG
Sequence: MVRPKHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGKCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPTSSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPESKSEEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
What is the function of this protein?
Binds directly to activin and functions as an activin antagonist.  Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
What are the official names of this protein?
Follistatin, FS, Activin-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RSH_BRUAB
Sequence: MMRQYELVERVQRYKPDVNEALLNKAYVYAMQKHGSQKRASGDPYFSHPLEVAAILTDMHLDEATIAIALLHDTIEDTTATRQEIDQLFGPEIGKLVEGLTKLKKLDLVSKKAVQAENLRKLLLAISEDVRVLLVKLADRLHNMRTLGVMREDKRLRIAEETMDIYAPLAGRMGMQDMREELEELAFRYINPDAWRAVTDRLAELLEKNRGLLQKIETDLSEIFEKNGIKASVKSRQKKPWSVFRKMETKGLSFEQLSDIFGFRVMVDTVQDCYRALGLIHTTWSMVPGRFKDYISTPKQNDYRSIHTTIIGPSRQRIELQIRTREMDEIAEFGVAAHSIYKDRGSANNPHKISTETNAYAWLRQTIEQLSEGDNPEEFLEHTKLELFQDQVFCFTPKGRLIALPRGATPIDFAYAVHTDIGDSCVGAKVNGRIMPLMTELKNGDEVDIIRSKAQVPPAAWESLVATGKARAAIRRATRSAVRKQYSGLGMRILERAFERAGKPFSKDILKPGLPRLARKDVEDVLAAVGRGELPSADVVKAVYPDYQDTRVTTQNNPAKAGEKGWFNIQNAAGMIFKVPEGGEGAAAKVDPAATTPKPGKRALPIRGTNPDLPVRFAPEGAVPGDRIVGILQPGAGITIYPIQSPALTAYDDQPERWIDVRWDIDDQMSERFPARISVSAINSPGSLAEIAQIAAANDANIHNLSMARTAPDFTEMIIDVEVWDLKHLNRIISQLKESASVSSAKRVNG
What is the function of this protein?
Functions as a (p)ppGpp synthase.  In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.  Plays a role in adaptation of Brucella to its intracellular host environment.
What are the official names of this protein?
GTP pyrophosphokinase rsh, (p)ppGpp synthase, ATP:GTP 3'-pyrophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the RelA/SpoT family.
Protein: UBID_PSEPK
Sequence: MQYRDLRDFIRGLEQRGELKRIQVPISPVLEMTEVCDRTLRAKGPALLFEKPTGFDIPVLGNLFGTPERVAMGMGAESVSELREIGKLLAFLKEPEPPKGLKDAWSKLPIFKKVVSMAPKVVKDAVCQEVVVEGDDVDLGTLPIQHCWPGDVAPLITWGLTVTRGPNKDRQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCEKNPGQPFPVAVALGADPATILGAVTPVPDTLSEYAFAGLLRGNRTELVKCRGSNLQVPATAEIILEGVIHPGEMAPEGPYGDHTGYYNEVDSFPVFTVERITHRQKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATHKWPGETTREWGRVIVKDEAVTRRIDELWDQLGID
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VSR_WTV
Sequence: MDASVDRITNLHFEILAKAGGHEIHQKYEAIRKLNLTGDSSKSNISVSARSAILKWADAKQGYIASQLDDRDYGDLIAKAVIFVPMSVITGGKNPKDLIPYGVVAAVLIFVPETLTLLDEIVINLMHDKKPLSSILLTKILRDMKIDVCGSNFDSFYYCPISRYNRHIIKLAGALPQMPTSVRLSVNDLARVAISEVHNQLISDKQMFFKLPTGFSPKVHCLKVLCTTEMEIFQKWVRTFMSDRPNEFIYSDQFNILSRTTYFSSDDPFSFFTLWRGWSTYKEILSQDQASSFLEAIGSGKPLRSSIATFPSMFDEGAIYIRYEWITPKDSANSKKAGSSAPSAPKM
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Suppressor of RNA-mediated gene silencing, Non-structural protein 10, Pns10.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus non-structural protein 10 family.
Protein: G7_VARV
Sequence: MAAEQRRSTIFDIVSKCIVQSVLRDISINSEYIESKAKQLCYCPASKKESVINGIYNCCESNIEIMDKEQLLKILDNLRCHSAHVCNATDFWRLYNSLKRFTHTTAFFNTCKPTILATLNTLITLILSNKLLYAAEMVEYLENQLDSSNKSMSQELAELLEMKYALINLVQYRILPMIIGEPIIVAGFSGKEPISNYSAEVERLMELPVKTDIVNTTYDFLARKGIDTSNNIAEYIAGLKIEEIEKVEKYLPEVISTIANSNIIKNKKSIFPANINDKQIMECSKMLDTSEKYSKGYKTDGAVTSPLTGNNTITTFIPISASDMQKFTILEYLYIMRVMANNVKKKNEGKNNGGVVMHINSPFKVINLPKC
What is the function of this protein?
Late protein which is a part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions (By similarity).
What are the official names of this protein?
Assembly protein G7.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae G7 family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Localizes in cytoplasmic virus factories and present in the virion core.
Protein: RL25_NEIMB
Sequence: MTYEIQASVREAQGTGASRRLRREGQIPGILYGEGQEPVAIAVDHKTVFYALEKESFHTALIKLSLNGETKDVIVRDFQMHPFRREVQHIDFQAVKADQLVRIRVPLHIVNAENSQAVKLQGGRVSLLNTSVEVVALPANIPAFLDLDCAEVVAGDILHLSDIKLPEGVESVSLKRNENLAVATVTGKKR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SPED_CLOPE
Sequence: MLGLKEKICLYGFNNLTKTLSFNIYDICYAKTEREKEDYIKYIDEQYNSERLTKILCDVTEMIGAHVLNISKQDYEPQGASVNVLITEEALPVALIDPSCNKGELSYLELRDSVVGHLDKSHLTVHTYPEFHPNNDIISFRVDIDVSTCGKISPLNALDYLIGSFDSDVITIDYRVRGFTRDVDGRKCYIDHDIKSIQDYIDGETLKKYDAMDVNVYQSNIFHTKMMLKDIVLNNYLFNSDPYELSPNDRREIRDRISKEMIEIYGGVNIY
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: TDRP_HUMAN
Sequence: MWKLGRGRVLLDEPPEEEDGLRGGPPPAAAAAAQAQVQGASFRGWKEVTSLFNKDDEQHLLERCKSPKSKGTNLRLKEELKAEKKSGFWDNLVLKQNIQSKKPDEIEGWEPPKLALEDISADPEDTVGGHPSWSGWEDDAKGSTKYTSLASSANSSRWSLRAAGRLVSIRRQSKGHLTDSPEEAE
What is the function of this protein?
Contributes to normal sperm motility, but not essential for male fertility.
What are the official names of this protein?
Testis development-related protein, Protein INM01.
What is the protein family that this protein belongs to?
Belongs to the TDRP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear. Also detected in cytoplasm near the midpiece of the flagellum.
Protein: TPT1_BRAOB
Sequence: MESRVLLRATETVTGVPQLRRPIRAINRQFSTASSSFTAFAKPIGSIGEGGNLISGRQLRPLLLLDSLPEKREILKPVRAASAEGGDSAGETKVGFLGKYPWLVTGILLLMWYFLNVIFNILNKKIYNYFPYPYFVSVIHLFVGVVYCLVSWSVGLPKRAPVNSDILKVLIPVAVCHAIGHVTSNVSFAAVAVSFTHTIKALEPFFNASASQFLLGQPIPITLWLSLAPVVLGVAMASLTELSFNWLGFISAMISNISFTYRSIFSKKAMTDMDSTNVYAYISIIALFVCLPPAIIVEGPQLLKHGFNDAIAKVGMTKFISDLFWVGMFYHLYNQLATNTLERVAPLTHAVGNVLKRVFVIGFSIVIFGNKISTQTGIGTGIAIAGVALYSVIKAKIEEEKRQGKTA
What is the function of this protein?
Mediates the export of fixed carbons from the chloroplasts into the cytosol in the form of triose phosphates.
What are the official names of this protein?
Triose phosphate/phosphate translocator, chloroplastic, cTPT.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein. Note=Located in zones of contact between the inner and outer membrane of the chloroplast.
Protein: RBM5_MOUSE
Sequence: MGSDKRVSRTERSGRYGSIIDRDDRDERESRSRRRDSDYKRSSDDRRGDRYDDYRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVRLMKRKTGVSRGFAFVEFYHLQDATSWMEANQKKLVIQGKHIAMHYSNPRPKFEDWLCNKCCLNNFRKRLKCFRCGADKFDSEQEVPPGTTESAQSVDYYCDTIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLLQILQSLHPPLKIDGKTIGVDFAKSARKDLVLPDGNRVSAFSVASTAIAAAQWSSTQSQSGEGGSVDYSYMQPGQDGYTQYTQYSQDYQQFYQQQAGGLESDTSATSGTTVTTTSAAVVSQSPQLYNQTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGTKYAVPDTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAEASSNQQTGLPSTKEGKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADAGFALFEKKGALAERQQLLPELVRNGDEENPLKRGLVAAYSGDSDNEEELVERLESEEEKLADWKKMACLLCRRQFPNRDALVRHQQLSDLHKQNMDIYRRSRLSEQELEALELREREMKYRDRAAERREKYGIPEPPEPKRKKQFDAGTVNYEQPTKDGIDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGAGLGAKGSAYGLSGADSYKDAVRKAMFARFTEME
What is the function of this protein?
Component of the spliceosome A complex.  Regulates alternative splicing of a number of mRNAs.  May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron.  May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2.  In the case of FAS, promotes production of a soluble form of FAS that inhibits apoptosis.  In the case of CASP2/caspase-2, promotes production of a catalytically active form of CASP2/Caspase-2 that induces apoptosis (By similarity).
What are the official names of this protein?
RNA-binding protein 5, Putative tumor suppressor LUCA15, RNA-binding motif protein 5.
What is the protein family that this protein belongs to?
Belongs to the RBM5/RBM10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURD_ALIF1
Sequence: MSGFGGVKNVVVVGLGMTGLSVVKHLLKTTISLTIKVIDTRDTPPGHDQLPENVELHSGGWQQDWLINADLIVTNPGIALASPQLKPAIDKGIKIVGDIELFAWAVNAPVIAITGSNGKSTVTDLTGEMAKAAGVKTAVGGNIGFAALDLLEQDAELYVLELSSFQLETTSTLKLKAAAFLNLSEDHMDRYQGMADYRQAKLRIFEHAEVCIVNRDDKQTYPDVEKTLKSFGFDQGDYGCIEKDGIEYLAKNTVPLLAANELGLVGKHNIANSLVAIALLDAAGINLDATLDTLRTYNGLTHRCQVVADNNGIRWVNDSKATNVASTLAALSGLQLEGKLHLLVGGVGKGADFSELSPALHDLNLMMYCFGEDGDQFVSLDPRSLLCETMNEAIATLYPTLNKGDMVMLSPACASFDQYANFMARGDAFTQLAKQYSIES
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_SORC5
Sequence: MERWFWIGLGGAAGTLARYGLSTWCQQRFGAEFPYGTLAVNVIGSFLLGAIGEIAATTELLSPTLRLSLSTGVMGGFTTYSSFNNETIRLIEYKSWAAGLANIAITLVVCLLAGVLGMVVARRLIAG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB_PHYMT
Sequence: MKLNKNSELKLSTIDEKEKNLRPETLKEYMGQKNLKEILSVYIKAAKKRKESLEHLLIYGPPGLGKTTLAKIVAKELNVNFKITSGAAMERSGDLVATLSSLQMGDVLFIDEIHRLPKSIEEILYSAMEDYVLDIVLGTENEKKSIRIDLPPFTLIGATTRFGDISSPLRDRFGLILKLNYYSEDELELIIKRTSLVYNTKIDNNTLKKLVKRSRGTPRIANRLFRRIRDFADVYNKGLIDEHISEIALEKLTIDKNGLDDADYTYLKSLIEKFEGGPVGIKNIAANIGEEVSTIEDIYEPYLLKEGYIKRTKRGRIATPLTFKLFKNDKIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS9_STRP7
Sequence: MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDSRKVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.