PharMolix/UniProtQA huggingface dataset:
Protein: WDR59_YEAST
Sequence: MCSSINEGPYNSPTFGKSLSLKVDGGFNAVSINPSGRDIVLASRQGLYIIDLDDPFTPPRWLHHITPWQVADVQWSPHPAKPYWIVSTSNQKAIIWNLAKSSSNAIEFVLHGHSRAITDINFNPQHPDVLATCSVDTYVHAWDMRSPHRPFYSTSSWRSAASQVKWNYKDPNVLASSHGNDIFVWDLRKGSTPLCSLKGHVSSVNSIDFNRFKYSEIMSSSNDGTVKFWDYSKSTTESKRTVTTNFPIWRGRYLPFGEGYCIMPMVGGNNAVYLINLCDDDDSEQNKKTKLQPIYAFKGHSDRVIDFLWRSRHTCDGDYDDREFQLVTWSKDCDLKLWPISDSIYGKVNFDRGKRLEEKLPDYDYCSYNKEPENRENVQKNEFRRLRENFVTTSGLKKNKTNHITWLSGIRMNSATSQEDLFNETKIQNLGEEVSAIGHKFPKVVFEKISVSTRELCLTLNGPWSEENPDDYIFLRISINFPLNYPNKGDPPKFTIEENSNLTMSKRQEILSNLATIGQKYTDSNLYCLEPCIRFVLGEKVSLEDIEEGQEPLLNFDIADHIDFEELSSLDSSYSDSQNPENLSSQSDIESYKEALVFPDTSNQGLDFGRNLALDTTPVPNGCGSCWTATGELFCFFANEKKPEKKQNAIIKLSQKEAGVEKHPFKIEPQVLYDKEVDSSVITAADELKARPKRYVDTLGLGGGTNGDSRTYFDDETSSDDSFDSVADDWDDILRNDIIVRTKIPILRGNFKAFSSVHSESGKTVESTKKNKNLVISKNFSSLLSDRKELALEYLFMDATPEGFARNNALVAEKFDLDEISHCWQILSDMLIDQSDYDPYTTIWNNHPMGIKWFIKEAIVYFERQQNLQMLAMLCCVILSARRKKIPARYYGQELENMEGTIVFNDNESQNTSFWKGSDAFSTRSRSSTVTPNFYGNHLRGKNIHGGDNSSIRSDDHHARLRTHNTLNGSSKFTEPAQKQGSRAISSSPFHSRMPDIKVELLHDDIIEAYEQEDLLHLEVSDIPKFQTYIYQYSKLLFRWGLPLERVKILKVSTDFRSSYSSQGIPPNNNKKSPYNGVLTHWIENNEFGEEKFLARNCNYCDLRVTRSSFICGNCQHVLHSSCARIWWEIGDECPSGCGCNCPEMFDA
What is the function of this protein?
Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis.  May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 5, SEH-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR59 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: YCCT_SALHS
Sequence: MKTGALATFLALCLPATVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: RPOY_STRU0
Sequence: MIYKIFYQETKERSPRREKTQALYLEIDAETELEGRIKARKLIEEKTAYNVEYIELLSDKHLEYEKETGVFALTEL
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: HIS7_BURL3
Sequence: MRVAEVVRNTSETQIRVKLNLDGTGQQKLATGVPFLDHMLDQIARHGLVDLEVEAHGDTHIDDHHTVEDVGITLGQAVAKAIGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGINAHHQLETVFKAFGRALRAAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_ACIBT
Sequence: MAKVETKNEGLVEKLVAVDRVAKVVKGGRIFSFTALTVVGDGNGRVGFGRGKAREVPAAISKALEAARRNMITVDLAGTTLQHPVNARHGASRVYMQPASEGTGVIAGGAMRAVLEAAGVHNVLAKCYGSTNAANVVNATFKGLRDMTSPEKVAAKRGKSVEEIQG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LUXS_STAAS
Sequence: MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MURQ_YERPN
Sequence: MSLGALISESRNPATMELDKLSTLAMLTCINDEDRKVPDAIRLVLPAVAQAVDLAADALKQGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDIALGMRDLQDLQLTATDMVVGLAASGRTPYVIGALRYARELGCPTAAISCNPDSPIAQEAQVAISPVVGPEALTGSTRMKSGTAQKLVLNMLSTGAMVKLGKVYQNLMVDVKATNVKLVDRACRIVVEATGVSRAEAEHALRQTDFEVKPAILMLLKGVSAEQARQDLRQHHGYLRAAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: SURE_THEPD
Sequence: MKILVTNDDGPFSPGLAILREAVRGLGEATVVVPETPKSATGLGLTLHKPLRVNRLSLDGEPVYLVSGTPSDVIYIAMNVISGKPDLVVSGVNIGDNLSVQVILTSGTLGAVLQASIEGVPGIAFSAAVDTPEELEEGEYRNFVLRSTKAIVRAVVGEGFPKGVDALNVNFPSVIASDVVVVRPALKRFSTAVVRRKDPQGRPYYWLYGHPVEAEEGSDVHAVLEEGKIAITPLSLSGMLSYSPEALSGIVKKVKEELSR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP195_YEAST
Sequence: MNSLIPLLVEASTYIVRGESSISIAIGIGPQASRSVPYHILCRGCDGTVTTFRTWHTQPLGPCNTIIIGRKGNETTGGAEQRRQQHLTSDSATKASLVGFCGLYYYFRK
What are the official names of this protein?
Uncharacterized protein YPR195C.
Protein: RHPA_HELP8
Sequence: MELNQPPLPTEIDDDAYHKPSFNDLGLKESVLKSVYEAGFTSPSPIQEKAIPAVLQGRDVIAQAQTGTGKTAAFALPIINNLKNNHTIEALVITPTRELAMQISDEIFKLGKHTRTKTVCVYGGQSVKKQCEFIKKNPQVMIATPGRLLDHLKNERIHKFVPKVVVLDESDEMLDMGFLDDIEEIFDYLPSEAQILLFSATMPEPIKRLADKILENPIKIHIAPSNITNTDITQRFYVINEHERAEAIMRLLDTQAPKKSIVFTRTKKEADELHQFLASKNYKSTALHGDMDQRDRRASIMAFKKNDADVLVATDVASRGLDISGVSHVFNYHLPLNTESYIHRIGRTGRAGKKGMAITLVTPLEYKELLRMQKEIDSEIELFEIPTINENQIIKTLHDAKVSEGIISLYEQLTEIFEPSQLVLKLLSLQFETSKIGLNQQEIDAIQNPKEKTPKPSHKKTPQHERARSFKKGQHRDRHPKTNHHSKKPKRR
What is the function of this protein?
DEAD-box RNA helicase probably involved in RNA degradation.  Unwinds dsRNA in both 5'- and 3'-directions (By similarity).  Background RNA-dependent ATPase activity is stimulated about 5-fold by RNaseJ (rnj).  Stimulates the dsRNase activity of RNase J.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase RhpA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The RNaseJ-RhpA complex co-localizes with 70S ribosomes and polysomes; remains associated with ribosomes in the absence of RNase J.
Protein: RS13_BACCN
Sequence: MARIAGVDIPRDKRVVISLTYVFGIGRTTAEKILAEAGVSEETRVRDLTEDELGRIRDIIDRIKVEGDLRREVSLNIKRLMEIGSYRGLRHRRGLPVRGQNSKNNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: HMP_PHOPR
Sequence: MISQQTIDIVKATAPVVAETGPKLTAHFYERMFNHNPELKDIFNMSNQRNGDQREALFNAICAYANNIDNLAALLPAVEKIAHKHTSFMITAEQYQIVGGHLLATIDELLSPGQEVLDAWGEAYGVLANVFITREEAIYQENEEKTGGWRGTREFTLIEKTQESDVITSFTFKPADGGTVSNFKPGQYLGIYLTPDAFEFQEIRQYSLSSAPRTDNYRISVKREEGGKVSNYLHNELTVGDTVQLAAPAGDFFLDVPATTPVTLISAGVGLTPTLSMLDALTEHQASVHWLHATENGSHHAFKDYVNTLADKYDHISATTWYREPLATDRPAEDFDYQGMIDLKAVASQLIDPAMHYYFCGPVGFMQHVAKQLIELDVQEDNIHYECFGPHKVL
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: PMI12_ARATH
Sequence: MKFLVSLVIFSLFLNGFATAQTLIQDSCKKAFAKDPQLSYDFCVNSLTQDPQSKAATTLESLVLASTKTAAAKITNLKGIVAQDLKDQRYQDIVEDLKLCLGFYNDANDDLTTALANIKSRDYQGANINLSAALDVPGNCEDDFKEAKKTSPITNENSILFKTILIPLAFTNML
What is the function of this protein?
Pectin methylesterase (PME) inhibitor involved in the maintenance of cell wall integrity in response to necrotrophic pathogens.  Modulates PME activity and pectin methylesterification during infection by Botrytis cinerea and contributes to resistance against the pathogen.
What are the official names of this protein?
Pectinesterase inhibitor 12, Pectin methylesterase inhibitor 12, AtPMEI12.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RPNA_ECOLI
Sequence: MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKTLKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAAMQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVTVMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQTGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADIMRFTGLSEEELAAASQ
What is the function of this protein?
A low activity DNA endonuclease yielding 3'-hydroxyl ends, equally active on ss or dsDNA, not active on dsRNA (PubMed:28096446).  Shows no sequence specificity (PubMed:28096446).  Upon expression enhances RecA-independent DNA recombination 49-fold, concomitantly reducing viability by 88% and probably inducing DNA damage as measured by induction of the SOS repair response in RecA cells (PubMed:28096446).  RecA-independent DNA recombination leads to replacement of recipient genes with large segments of donor DNA rather than DNA addition to the donor strain; increased expression of RpnA leads to smaller replacement segments, suggesting this protein may play a role in generating crossover events (PubMed:28096446).
What are the official names of this protein?
Recombination-promoting nuclease RpnA.
What is the protein family that this protein belongs to?
Belongs to the Rpn/YhgA-like nuclease family.
Protein: RAG1_ONCMY
Sequence: MEETYAPRCSMPAELHHPYSKFSDWKFKLFRVRSMERAPLPGEMQLERGALSGVVASAPLGETVGDVVGLPGSVMKLWLGGKSKENVEGPGKRVDLKLQEMDTYMNHLRCLCRLCGGALRKAKGPEHEVQGLLDEASMSALRRVGCKATSWPEVILKVFKVDVAGDMEVVHPPFFCQRCWTLAMRGGGFCSFSRTHVPGWRPHTTLCLLCTPRNPHYRGERKRRKPTRGAQHLAKRTKWDLQDNAAIVGEKRAWRTVIDPPQGPGLRPWVRSSVQRAQWVKSITLCQKEHLSARLLSEDLPVDFLSSVTCQVCDHLLSEPVQSPCRHLFCRSCIAKYIYSLGPHCPACTLPCGPADLTAPAKGFLGVLHSLPLLCPRESCGEQVRLDSFRAHCLGHHLEEVDGDHKSAENSLDNFLPVNKGGRPRQHLLSLTRRAQKHRLRDLKTQVKVFAEKEEGGDTKSVCLTLFLLALRAGNEHRQADELEAMMQGRGFGLHPAVCLAIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRTAEKELLPGYHPFEWQPALKSVSTSCHVGIIDGLSGWIASVDDSPADTVTRRFRYDVALVSALKDLEEDIMEGLRERGLEDSACTSGFSVMIKESCDGMGDVSEKHGGGPPVPEKPVRFSFTIMSVSIQAEGEDEAITIFREPKPNSEMSCKPLSLMFVDESDHETLTGVLGPVVAERNAMKHSRLILSVGGLSRSFRFHFRGTGYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMTLHSVTRSHDENLERYELWRTNPHSESAEELRDRVKGVSAKPFMETQPTLDALHCDIGNATEFYKIFQDEIGEVYHKANPSREQRRSWRAALDKQLRKKMKLKPVMRMNGNYARKLMTREAVEAVCELVCSEERQEALRELMGLYIQMKPVWRSTCPAKECPDELCRYSFNSQRFAELLSTVFKYRYDGKITNYLHKTLAHVPEIVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELEDVLKHHWLYTSKYLQKFMEAHKDSAKALQATIDTVGSQETQEDADMSLDVPDF
What is the function of this protein?
Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination.  V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments.  In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment.  RAG2 is not a catalytic component but is required for all known catalytic activities.  DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.  In addition to its endonuclease activity, RAG1 also acts as an E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H3.  Histone H3 monoubiquitination is required for the joining step of V(D)J recombination (By similarity).
What are the official names of this protein?
V(D)J recombination-activating protein 1, RAG-1.
What is the protein family that this protein belongs to?
Belongs to the RAG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP52C_CANMA
Sequence: MAIEQIIEEVLPYLTKWYTILFGAAVTYFLSIALRNKFYEYKLKCENPVYFEDAGLFGIPALIDIIKVRKAGQLADYTDTTFDKYPNLSSYMTVAGVLKIVFTVDPENIKAVLATQFNDFALGARHAHFDPLLGDGIFTLDGEGWKLSRAMLRPQFAREQIAHVKALEPHVQILAKQIKLNKGKTFDLQELFFRFTVDTATEFLFGESVHSLYDEKLGIPAPNDIPGRENFAEAFNTSQHYLATRTYSQIFYWLTNPKEFRDCNAKVHKLAQYFVNTALNATEKEVEEKSKGGYVFLYELVKQTRDPKVLQDQLLNIMVAGRDTTAGLLSFAMFELARNPKIWNKLREEVEVNFGLGDEARVDEISFETLKKCEYLKAVLNETLRMYPSVPINFRTATRDTTLPRGGGKDGNSPIFVPKGSSVVYSVYKTHRLKQFYGEDAYEFRPERWFEPSTRKLGWAYLPFNGGPRICLGQQFALTEASYVIARLAQMFEHLESKDETYPPNKCIHLTMNHNEGVFISAK
What is the function of this protein?
Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids.
What are the official names of this protein?
Cytochrome P450 52A3-A, CYP52A3-A, Alkane-inducible P450-ALK1-A, CYPLIIA3, Cytochrome P-450ALK, Cytochrome P450-CM1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane. Membrane; Single-pass membrane protein.
Protein: LPXD_ALKEH
Sequence: MTETVTVSELAEGLGAELVGKPTRVIRRVATLCDAGPDAIGFCSNANYLEDLRATGAGAVIVRAEHVAECPTTALVVDDPYYAYAAVATRLHPAERPPAGVHPTAVVAEGVTLGEAVSVGPHAVVEAGARLGARTIVGPGCHVGTGVEIGEDSHLMGRVTVADRCVVGCRVILHPGVVVGADGFGFAKGPGKAGWRKVPQLGRVILGDDVDLGANTTVDRGAIDDTVLEEGVKLDNQVHIGHNVRVGARTIIAGNTVVAGSTTIGCDCMIGGSSAITGHISIADGVILMGMTGVTGSIKQPGAYASPLPAKPVREWRRNSVRFTQLDDLFRRVKRLEAAQSTGEGDGGDDGD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LOX4_ARATH
Sequence: MALANEIMGSRLIFERSSSLASPFHSRFSIKKKTQRTQFSINPFDPRPMRAVNSSGVVAAISEDLVKTLRISTVGRKQEKEEEEEKSVKFKVRAVATVRNKNKEDFKETLVKHLDAFTDKIGRNVVLELMSTQVDPKTNEPKKSKAAVLKDWSKKSNSKAERVHYTAEFTVDSAFGSPGAITVTNKHQKEFFLESITIEGFACGPVHFPCNSWVQSQKDHPSKRILFTNQPYLPSETPSGLRTLREKELENLRGNGKGERKLSDRIYDYDVYNDIGNPDISRELARPTLGGREFPYPRRCRTGRSSTDTDMMSERRVEKPLPMYVPRDEQFEESKQNTFAACRLKAVLHNLIPSLKASILAEDFANFGEIDSLYKEGLLLKLGFQDDMFKKFPLPKIVTTLQKSSEGLLRYDTPKIVSKDKYAWLRDDEFARQAIAGINPVNIERVTSYPPVSNLDPEIYGPGLHSALTEDHIIGQLDGLTVQQALETNRLFMVDYHDIYLPFLDRINALDGRKAYATRTILFLTRLGTLKPIAIELSLPSQSSSNQKSKRVVTPPVDATSNWMWQLAKAHVGSNDAGVHQLVNHWLRTHACLEPFILAAHRQLSAMHPIFKLLDPHMRYTLEINAVARQTLISADGVIESCFTAGQYGLEISSAAYKNKWRFDMEGLPADLIRRGMAVPDPTQPHGLKLLVEDYPYANDGLLLWSAIQTWVRTYVERYYANSNLIQTDTELQAWYSESINVGHADHRDAEWWPKLSTVEDLVSVITTIIWLASAQHAALNFGQYPYGGYVPNRPPLMRRLIPDESDPEFTSFIEDPQKYFFSSMPSLLQTTKFMAVVDTLSTHSPDEEYIGERQQPSIWTGDAEIVDAFYGFSAEIGRIEKEIDKRNRDPSRRNRCGAGVLPYELMAPSSEPGVTCRGVPNSVSI
What is the function of this protein?
Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).  13S-lipoxygenase that can use linolenic acid as substrates.
What are the official names of this protein?
Lipoxygenase 4, chloroplastic, AtLOX4, LOX3-like protein.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMPN_RAT
Sequence: MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTEYLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS
What is the function of this protein?
Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases.  Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines.  May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells.  May have a role in angiogenesis and promote cholesterol crystallization.  May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity).
What are the official names of this protein?
Aminopeptidase N, AP-N, rAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Kidney Zn peptidase, KZP, Microsomal aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Also found as a soluble form.
Protein: Y045_HAEIN
Sequence: MKKQILALVCGVIFSSSTWAHNLQLEQSLPSVKVSEYGEIVLSGKDTVFQPWGSAELAGKVRVVHHLAGRTAAKEXNQSMIDVIKASHFNPVKYQTTTIINADDAIVGTGMFVKNGAKKGKQENPHSQVVLDDKSAVKNAWGLNSKDSAIIVLDKTGKVKFVKEGKLSDSDIQTVISLVNGLTK
What are the official names of this protein?
Uncharacterized protein HI_0045.
What is the protein family that this protein belongs to?
To E.coli YtfJ.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLO2_NEIMF
Sequence: MKITPVKALTDNYIWMIQHGNHAVCVDPSEPSPVLEFLVRNRLMLAQTWVTHPHPDHEGGAAALWRGYMESPVYGESDIEAATHTVTAGTQFTFGDGQVTVWATPGHTDRHTSYLLETSDGIHVFCGDTLFSAGCGRVFTGTIEQLYDSFQRFNRLPENTLFYPAHEYTAANLDFAAHIEPDNADIQTALKAAAHTPTLPVTLAHERRVNPFLRVDLPHVRDRAEALSGKTLNSSLDTFVALRELKNQYRTK
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RLMN_XANOP
Sequence: MNEVVIPSVLQDVPVRTSEPRKQNLLDLDREGLERFFADTLGEARYRAHQVMKWIHHRYVTDFDHMTDLGKALRAKLHQHAEVLVPNVVFDKPSTDGTHKWLLAMGTDGKNAIETVYIPDKGRGTLCVSSQVGCGLNCSFCSTATQGFNRNLTTAEIIGQVWVAARHLGNVPHQQRRLTNVVMMGMGEPLMNFDNVVRAMSVMRDDLGYGLASKRVTLSTSGLVPMIDRLSTESDVSLAVSLHAANDALRETLVPLNKKYPIAELMESCARYLRGSKKRDSVTFEYTLMKGINDQPEHARQLARLMRQFDNAVQSKDAGKVNLIPFNPFPGTRYERSGETEIRAFQKILLDAQVLTIVRRTRGDDIDAACGQLKGQVMDRTRRQAEFRRTLEGQADRDAAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PYRAR
Sequence: MAKYVVGSAWPYVQTVPHLGNMIGSVLSADVYARYLRLRGHEVVFVSGSDMHGTPIEVEAIQLGVDPADYALKMHQIVAELFRRWDISFDLYTHTHSETHIKFVQEFFARVYENGFIFTRDDEVPYCPRDKIYLPDRFVIGKCPYCGYERARGDQCENCGRLLDPKQLIEPRCAVCGSKPEWRVTRHWYLDLRRLEDRIRKYVEGNPHLPLNAKEMSLAMLKEGMRPRAITRDNKWGIPAPFPGAEGKTIYVWFEAVLGYISAVVEYFKKLGREEEWKRFWLDQETKVVFFVGKDNVPFHVIILPALLMASGENYVMPTTTASTEYLLYEGDKFSKSRRWGIWIDEALHLLPTDYWRFVLVYIRPENRDTSFTWQTALEVINKVLNDDVGNYANRVLSFIKSRMGGAVPPPGKPSPEDEEFISKVAQLFQKAEAHYDAIELKEAVHTVVEIAREGNKYLNARAPWELAKKDAEAANAVLYRAFWSLKYLAAGLAPVVPRSAETLWAMMGISTPLTWEEAKKPPTPGAQLGEVKPLFRKITEQDVKVLLAKLEELRAQKYSRKYPWEQVLL
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.