PharMolix/UniProtQA huggingface dataset:
Protein: NEP_I77A9
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQLESLKLYRDSLGEAVMRMGDLHSLQSRNEKWREQLSQKFEEIRWLIEEVRHRLKNTENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TRI5_FUSMI
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQMLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPHPAMLNYFDDLQAGREQSHPWWALVNEHFPNVLRHFGPFCSLNLIRSTMDFFEGCWIEQYNFGGFPGSDDYPQFLRRMNGLGHCVGASLWPKDLFDERKNFLEITTAVAQMENWMVWVNDLMSFYKEFDDERDQISLVKNFVTCHEITLDEALEKLTQETLHSSKQMVAVFADKDPQVMDTIECFMHGYVTWHLCDARYRLHEIYEKVKDQDTEDAKKFCKFFEQAANVGAVAPSEWAYPQVAQLANVRAKDDMKEGQKPILSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: HSLV_DECAR
Sequence: MEQYHGTTILSVRRGNSVAMGGDGQVTLGNIVIKATARKVRRLYNGRILAGFAGGTADAFTLFERFEAKLDKHQGNLLRSAVELAKDWRSDRALRRLEAMLSVADREVSLIITGNGDVLEPEQGIVAIGSGGSYAQSAARALLENTELAPRDIVTKSLEIAGDICIYTNRNFTLEVLE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_MUSLU
Sequence: VHLTAEEKAAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPDAVMGNPKVKAHGKKVLNSFSEGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RK2_CHAGL
Sequence: MGIRLYKAYTPGTRNRSISDFKELKNNKPEKSLTSSYHKKQGRNNRGIITIRHRGGGHKKLYRQIDFERNKFNIPGQVKSIEYDPNRNTRISLIHYEDGEKRYILAPRGLNIGDKIISSEEADITIGNTLPLTKIPLGTAIHNIEIKPGKGGQLVRSAGTVAQLIAKEGLVATIRLPSGEVRTIGKNCLATIGQLGNVDSNNRSFGKAGSKRWLGKKPTVRGVVMNPVDHPHGGGEGRAPIGRKRPLTPWGRPALGKKSRKNHKYSDAFIIRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GEFL_DICDI
Sequence: MKSMSSGGINKLFEGSLSKDGKTSRIEHQKIKQSGCPLLIKLMKDNGHITNVIIKSCRLKVLPGEISSLGGHLKKLHIEDNKIQEIPNLEQLEQLEELILPNNDIAKFQVSISKLTTLRLLDLSGNQLGTIPVRLFSLVSMRELYLDENQFSNFPSHLCELQKLTTLGFSNNLLKSIPTQIGQMIGLKKLILSGNQMESIPMEISNLKSLTHLDCSSNILSSIPNELGNKLSQLSFLFLQHNKLRSIPDEIGQCQSLVSLRLNNNSITLLPQSIGELENLQELYLQENRLNTLPSELGNCCSLKKLYLEFNKLIALPDRFKRLHCLNVLSLHDNLLDDLPNFLSLEFSQHLIRFTIHNNPFLRENGIDVIDSLQFLNSHLLSIQNFINNHDQQNDNSNNNNNNNNTTTTTTTTTTTTTTSTTNNNNTLFTDSYLSSASSSSFLNKSPSGLSLVGSFNGTIKKSISNSSNMNGSGSNGVGHGSGLTPKLNFKSLITSRDFSSDSDSDTDSTSSFSTYSSSTINTKRASISPRTSLTLSNSASNDSVSAVANGNGNNNNNNNNNNNNNNNSNNNNSGLVNSISSFSLSSGQINYYNISRARRGTHGNDQPHQTISPSTSTEKLQQTVSTPRQQSFFISVLNRRKSSLNNSQNGNNSNNNSNNNNNNSNNNISSLSSSNFANSLYNPLMSSSPTSSPSSSYSNLHSSFNGTSTPPFSSPSQSSPLSNSINGIHCNYSNNNNNNNNSNNNNNNNNNNNINNNNNNSNNNNNINTNGNNNSFNGIIMGSPIYKSFQSLYETLLDDLDYSKKRREELLNLSVEEKWIFLQRIKPDCTNSLVSNGVYQLQHQISSNDLKTLISSPPKLNSSQQLLSSSSSSSSLSSSSTSATHSLQNKSLPSISVCPKSPRTHMKVLSASSLFTLEDITKLRQQLVSKPVSWVINFAESTGIVSILSMITTYSQNLINNVNKDQPQSQPQPQPQPQPRPQPQQPQPQQPQPQQLLPLLSQLQPQQQQQQQQQTQQPQPQLQAQTKSDDHFIINECLGCIKLLVELEMQSLLLNDTAEIIFPLILSSQVSTKRMTFEVLELICKIFSLGSTIVLESIKNYSKKINEPLTKVFSHITSPLDSEYPADLKVSCMSLINHLIGSNHLSLEARIETRSKFLSNDILLIIKNLRIDGEGIETSSWKQLELEMKQFESMMVQDDNQTSNAEANELVSNELSQSIDNNNNNNNNNNNNSSTNLVNNNNNNNINSNCNSIINGGNSSDSLINNSVGTGVGSIMGVGSFMGVNEIEYDSPRKEFDELKSSNNNNSNSNSVNNFINNITEPIMPLTPTEGKLVVIVSMQQTRQQAQLQQQLQQQLEEEDDDEVPLSSSVATTASTTANTTLIEPNHLPIQTREVIVSVQRKSQAGDVIRSLLASNSNLKELGEWGLFVNDSNSNNNNNNNNNNNNKLSTNVIGRFLKDDEYIFDQMTTSSTSGSLSSDDGATPRLMTRSIPRFKEYRLKMIPWKVRVSLEKVKEMGLVLNANNTANGQFNESKFIAEAPMDPTMTCTGLVYHLIKKYLPNVNDRYCLEADDFGLYLDTNAGGLMWGGGTGGGYWLEPLEKLHDYEIFKDPKSTVALKLRPKGVKLKFADGTYEIFRLDLMSPTEKIFQEISEKVIDSNNNINLSYYGIFVDRQQGGANGNGISDSPILVSQSSSTSLIEESKKQRKPEWLEKGLPLYHYKINSRCCLRFALRPSNITLLIDISLFKSFQQQQQQQQQQQQQSTSSSSSSSSSSSVSSNNNSTNNSNNLIGSLNNSINTISELDESIDDNGLSSSSSDKEDQISTPSTSNLLSKFQQVDESISNLKFQLPQPIQSKQIIVQLPLHLPLGEALETDENWIETGIEREKCSFHFDSFDGILMNQTQPLNTQNFTEKNRICVLMADELEINSEQTNHNKTNIWDEPFDSSTIICDPDNPGQIRAATLNKLLEQATNNIEKDRELMNILLMTYMSFATSDILLDKLVERYNVPEHEKEQKSVVQLHTIVFLKNWLEQQAPQAASGGGLEEKFLVRLSEFVDKQISLDGYTKIVPQLKKWIDSALKEKRAYAMPEAARPNQLTTKLPSLTSSLLDDELFVAQQLTLREYETFKRIQAVEFLGQAWGKPKLQYKAPNLLKMIERFNKISTGVSTAILSQPKIKTRVKLICRFIKIAQHCRDLNNYHLLTAFMAGIRNSNVVRLRLSWAKVPKKHLHILEDLEKIMSMEGSFKEFRTKMAETIPPCIPYLGVYLKDLTFIEEGNPDSINSLINWGKKKLIYNIISIIQRCQQVSYDFGNQNQSQVAQKSDLVLNYFDSLPIALDELLYKISLNLEPRSNFNN
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Ras guanine nucleotide exchange factor L, RasGEF domain-containing protein L.
Protein: DYR_THEMA
Sequence: MAKVIFVLAMDVSGKIASSVESWSSFEDRKNFRKITTEIGNVVMGRITFEEIGRPLPERLNVVLTRRPKTSNNPSLVFFNGSPADVVKFLEGKGYERVAVIGGKTVFTEFLREKLVDELFVTVEPYVFGKGIPFFDEFEGYFPLKLLEMRRLNERGTLFLKYSVEKSHR
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: SYE_BURTA
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMAWLGLDYDEGPYYQMQRMDRYREVLAQMQEKGLVYPCYMSTEELDALRERQRAAGEKPRYDGTWRPEPGKVLPEPPAGVAPVLRFRNPLTGTVAWDDAVKGRVEISNEELDDLVVARPDGTPMYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQGEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFTREQFVEWFDLEHLGKSPAQYDHNKLNWLNNHYIKEADDARLAGLAKPFFAALGIDAGAIEQGPDLVSVMGLMKDRASTVKEIAENSAMFYRAPAPGADALAQHVTDAVRPALVEFAAALKTVEWTKEAIAAALKAVLGAHKLKMPQLAMPVRLLVAGTTHTPSIDAVLLLFGRDVVVSRIEAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRFT_DRONO
Sequence: SCYNPCLPRSSCGPTPLANSCNEPCLFRQCQDSTVVIEPSPVVVTLPGPILSSFPQNTVVGGSSTSAAVGSILSSQGVPISSGGFNLSGLSGRYSGARCLPC
What are the official names of this protein?
Feather keratin, F-ker.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: RPPH_ACIBY
Sequence: MIDSEGFRPNVGIILANDDGQVLWAKRIGHNAWQFPQGGIQFGETPEQALFRELREEIGLLPEHVQIIAQTKGWLRYRLPHRYIRSDSDPVCIGQKQKWFLLKLTAPAKNIQLNLADPPEFDEWQWVSYWYPLGQVVNFKRDVYRKAMVELCTQLPVQQLP
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: FUBP1_HUMAN
Sequence: MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
What is the function of this protein?
Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter.  May act both as activator and repressor of transcription.
What are the official names of this protein?
Far upstream element-binding protein 1, FBP, FUSE-binding protein 1, DNA helicase V, hDH V.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACEK_SALA4
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWEPLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYP7_YEAST
Sequence: MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Plays a major role in negative regulation of the heat shock transcription factor (HSF).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP7, PPIase CYP7, Rotamase CYP7.
Protein: APBA1_HUMAN
Sequence: MNHLEGSAEVEVTDEAAGGEVNESVEADLEHPEVEEEQQQPPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTDTAEGDVIAAARDGYDAERAQDPEDESAYAVQYRPEAEEYTEQAEAEHAEATHRRALPNHLHFHSLEHEEAMNAAYSGYVYTHRLFHRGEDEPYSEPYADYGGLQEHVYEEIGDAPELDARDGLRLYEQERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERPPTPAGGRPDSPGLQAPAGQQRAVGPAGGGEAGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQRPMDGDSPSPGSSSPLGAESSSTSLHPSDPVEASTNKESRKSLASFPTYVEVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRKKAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI
What is the function of this protein?
Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery.  May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.  Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).
What are the official names of this protein?
Amyloid-beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1, Mint-1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Only about 5% of the protein is located in the nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus.
Protein: MPIP3_HUMAN
Sequence: MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
What is the function of this protein?
Functions as a dosage-dependent inducer in mitotic control.  Tyrosine protein phosphatase required for progression of the cell cycle.  When phosphorylated, highly effective in activating G2 cells into prophase.  Directly dephosphorylates CDK1 and activates its kinase activity.
What are the official names of this protein?
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
Protein: ARO1_SCHJY
Sequence: MSQDTDVVSVPILGKEAVFVGFNLERRVCDFLIENAKSSAYVIVTDTNIAPHYLEKYTTALSEAAKRHGVAPRILTRVIPPGETSKCRSMKAEIEDWMLSQSCTRDTVLVAMGGGVIGDMAGYVAATFMRGIRFIQLPTTLLAMVDSSIGGKTAIDTPNGKNLVGAFWQPLAVFADLNFLETLEPRQFINGMGEVIKTAAMWNEKDFCLLEQNPTVILEAVHRPRVPGQFKFENIRNLLQKIILASVRTKCEVVTLDEREGGLRNLLNFGHSIGHAYEAILFPQILHGECVSIGMVKELELSRYLGILKPNAVGRVTKCLMSYTLPVSVHDAHIKKYAGYKKCPVDKLIRIMAVDKKNQGLQKRVVILKAVGETYEKHATVVSDEDIRVVLSHDIQVSPFDNSVSDVVVTPPGSKSISNRALILAAMAKGTTKLTNMLHSDDTQVMMAALEELGAATFSWEDNGETLVVNGGGKFKTPSKELYLSNAGTAARFLTTVAALVGENEQGGEVVLTGNHRMKVRPIGPLVDALRANGCSISYLEREGSLPLKMIPQNGLRGGVIELAATVSSQYVSSILMCAPYAQEPVTLKLVGGKPISQLYVDMTIAMMKGFGVNVVKSETEAYTYHIPKANYTSPGDYEIESDASSATYPLAFAAITGTKCTVPNIGSASLQGDARFARDVLAPMGCTVEQTPTSTTVQGPPMGQLKPLESVDMETMTDAFLTATALAAVACNSSGNEHITRITGIANQRVKECNRIAAMVHELAKFGVKAGELEDGIFIHGQSYKDLKTPEEGIYTYDDHRVAMAFSILTLVTPKPTVILDKACVVKTWPYWWDVLRNSFKIKLAGVESKETVKSVKLTRSRASVILIGMRGAGKTTIGSIIAGQLNMKFLDLDQELEKKLNTTIPDLVNTRGWDDFRQEELQVLQEFIDTKSSDFVAACGGGIVETPAARELLCKYVKEGGIVLHIHRNLDQVLSYLSIDKSRPAYADRESTKNVYLRRHQWYLDCRSHDFVSPTIESGNVQSKLETSMSRFLRVVTGKSTWFEKAIQKPHSFFLSLTFPNINDAISFLPEAIIGCDAVELRADLLEDPNSTTGYPSVEFVAEQFATLRAAIDLPIIFTVRSKDQGGRFPNANESEAVELMLAALRWGVDVLDLELGWSTESLQAIYARKENTKIITSWHDTAQRCSWAQPDEWLQKLDMATAFGDVVKFVGIAKSMQDNFDLEKFRKSFKGYTNKPLIAINMGTVGQLSRVFNNVLTPVTSPALPYKAAPGQLSVRQIITALSLMGSISPKKFYLFGTPIQHSKSPILHKTCYDLTGLPYTYDLFETESVEGVKDVLSQPDFGGANVTIPYKLDILQYLDELSDEARFLGAVNTVVPISENGKRKLRGDNTDWRGIVRTFVRAGANNLNGKNALVIGAGGTSRAAIFAMHKLGAKNIYLLNRTLVNAEKVKAVFPEEYNVKVIDHTKQSEISEWTKLQVAAVVSTVPADRPLPESVSKVIDALLSEIPAQKKEQYVFLDMAYKPLNTPLMSVASKHGYTCINGLEVLLQQGLASFEIWTGLAVPFEHVFGLYMVLCAKEHN
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC_SULAC
Sequence: MPKFNPKQMKDLERMLGLKTEQLNAVKVTIELQDKILVIDNPVVVKMLAQGQEVFSVMGSAREESKQQQKVEIKEEDVKFIMEQTGKSEKEAREALEKSNGDIAKAILALTEGENK
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: FBIC_MYCPA
Sequence: MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARGDDLADLCASAARVRDAGLQSAGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPEDRWPEAREWLEARGYDSTLSYVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYGSPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIEDYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVDDWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRLTAQPKYVQAGAAWIDPRVSGHVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGDWESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVAALADSLRRDTVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMHVHAFSPMEIANGVTKSGLSIREWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMMYGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAVHALARIMLHGRISQIQTSWVKLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKTVAELTAIAEGIGRPARQRTTDYTPLAA
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
FO synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
Protein: PSBE_BIGNA
Sequence: MAGTTGERPFSDILTSIRYWIIHSITVPSLFIAGWLFVSTGLAYDVFGSPRPNEYFSNGQQEAPIVLDRFGKL
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KTHY_ECOLC
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ENGB_LACE2
Sequence: MVIKKVNLDIVVGVTSTLPETPFPEVAFAGKSNVGKSSLINALMNRKSYARTSSQPGKTQTINFYNINDSMYLVDLPGYGYANVSPAVKAKWGKMIEKYLRKSSQLKQVFLLIDIRHDPSDNDRMMYDWIVNNGYRPVIVATKLDKIKRSQISKQVKAVRTGLGLRQEDILIPFSSQTKQGLKELWQLIDSYVLPQEENETDSESAAIIQE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TRM2_HHV6U
Sequence: MMDSSPEKTNLELLYERVCEQGREFEVVFYPMLPRLYEMMLPSLEARLNFLSVGYRHVAFARYVHGDVDCVHREVMAQKMVLLTSILSKLLNVNGILEHQEYLNTE
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: EVGA_ECO57
Sequence: MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKDNNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG
What is the function of this protein?
Member of the two-component regulatory system EvgS/EvgA.  Regulates the expression of emrKY operon and yfdX.  Seems also to control expression of at least one other multidrug efflux operon (By similarity).
What are the official names of this protein?
DNA-binding transcriptional activator EvgA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP4A1_MACFA
Sequence: MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
What is the function of this protein?
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis.  May play a role in the development and maintenance of differentiating epithelial tissues (By similarity).
What are the official names of this protein?
Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=And mitotic spindle.