PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_STRP7
Sequence: MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLKEVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVLPIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKENESVIIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L22_HYDST
Sequence: LSCYLGYKHSQTCPPGENVCFVKTWCDAFCSTRGERIVMGCAATCPTAKSGVHIACCSTDNCNIYTKWGSGR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Ast2b, Alpha-EPTX-Ast2b, Long neurotoxin 2, Toxin C.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_STAA8
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YKQ3_SCHPO
Sequence: MDKKEYCYYCFEVVAATLEHRKVRDKWNAKSWTRSIPLFVKFASGKGHDKQLRGCIGTFRARPLVTNLTYFSKQAAFCDERFRPISLGELALLECQIDLLVDFEPIDDPLDWEVGIHGVSIKFTANGIRYSSTYLPSVAAEQRWDQEETLESLIHKAGYYGSIRSLQITATRYKSLEIGCTYEEYLHNLELLG
What are the official names of this protein?
Uncharacterized protein C688.03c.
Protein: ESSB_STAAE
Sequence: MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEHFHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIKNLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPVSEAEFLTRYKALVICAFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTAFLDEQYQKQEQDYSQNYAYVRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLNTYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELGQGHLDEAINIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDKLQDILDKEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQAQKDKEKRQEAERKK
What is the function of this protein?
Component of the type VII secretion system (Ess) (Probable).  Required for the secretion of EsxA and EsxB (PubMed:15657139).
What are the official names of this protein?
Type VII secretion system protein EssB.
What is the protein family that this protein belongs to?
Belongs to the EssB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LUXS_GLAP5
Sequence: MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFVRPNIEILSPRGIHTMEHLFAGFMRDHLNSDTVEIIDISPMGCRTGFYMSLIGSPSAEEVAKAWEASMRDALEKVPDETKIPELNEFQCGSYKEHSLADAHEIVRNVLKQPIGINRNKDLALDEKLLNP
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y1804_MYCLE
Sequence: MWCPSVSLSVWANAWLAGKAAPDDLLDALSLWTPMQSVAAYDAVAAGHTGLPWPDIHDAGTVSLLQTLRTAVGRPTKSTPNDPHRLRGTINVVLPVPGDVHGLVTGTQFEHDALAASEAVIITNPHDSSTAVGLVPEYSYSNPEQYTNSEETRLSELSALSWVVYSLPGVPLFDHHELGDAEYALRSAVRSAADALGTIELNSATADITDPRGLVEQLLESSRQHRVPDHAPSRALRVLENAAHVDAIISVSTGLTPIGTHSLSDIEIASNALRPLTAVVRSARMAAVNAILHSAWPD
What are the official names of this protein?
Uncharacterized protein ML1804.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1486c, M.bovis Mb1522c and M.avium MAV321.
Protein: ATPA_THENN
Sequence: MRINPGEITKVLEEKIKSFEEKIDLEDTGKVIQVGDGIARVYGLNKVMVSELVEFVETGVKGVAFNLEEDNVGIIVLGEYKDIKEGHTVRRLKRIIEVPVGEELLGRVVNPLGEPLDGKGPINAKNFRPIEIKAPGVIYRKPVDTPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQGVYCIYVAIGQKKSAIARIIDKLRQYGALEYTTVVVASASDPATLQYIAPYAGCAMGEYFAYSGRDALVVYDDLSKHAVAYRQLSLLMRRPPGREAYPGDIFYLHSRLLERAVRLNDKLGGGSLTALPIVETQANDISAYIPTNVISITDGQIYLEPGLFYAGQRPAINVGLSVSRVGGAAQIKAMKQVAGMLRIELAQYRELETFAQFATELDPATRAQIVRGQRLMELLKQEQYSPMPVEEQVVVIFAGVRGYLDDLPVEAVRRFEKEFLRFMHEKHQDILDDIREKKELTPETEEKLKKAIEEFKAVFRV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SFSA_CLOAB
Sequence: MKIDNMTKLAKFVKRPNRFQAYIELEGEEMMVHVPNTGRCREILLPNCTVVLREENNPNRKTKYDLIGAYKGEKFINIDSQIPNKVVYEALYNKKVESLAKYNIIMKEKTFKNSRFDFRLENDEGEVYFLEVKGVTLEDKGVARFPDAPTERGAKHLKELVEAKKSGYGAGVLFLMQMDNISEFRPHDEMDKMFGEALRYAAINGVDVMAYECSVDEKSITLTKSVKIVL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RS5_THEP3
Sequence: MARVDWTKLDLKERVVSINRVSKVVKGGKNFRFSVTVVVGDAERGYVGVGRGKAAEIPDAIRKAIEDAKKHLIKVPIVGTTIPHEVIGEFGAGKVLLKPAREGTGVIAGGPVRAVLESAGIKDVLTKSLGSSNATNMVYATIEGLKRLRTAEDVAKLRGIPVSQLFE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PUR5_ANADF
Sequence: MSLTYRDAGVDIDEGDRLVELIKPHARPTLRPEVLAGIGGFGGLFALDVKKYREPVLVSGTDGVGTKLKVAFAANRHDTIGIDLVAMCVNDVAVVGAEPLFFLDYFGTGKLSAEQGAEVVKGIAEGCRQAGCALIGGETAELPGFYAPGEYDLAGFAVGCVERSRIVDGKGVAPGDVVVGVASTGLHSNGYSLARKALMDRHPLDRRFDGLGGRTLGEALLEPTRIYAKDVLALLDAVPVKAFSHITGGGLPGNVPRTLPDGTRAVLEEKRWPRPAIFDLVEREGGVPRDEMYRTFNMGLGLVAVVAPGDEAAAHAALRARGLDAWTVGQIEVGTGEATCEVVR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_BIFA0
Sequence: MAEGIVFDADAVSKDIAEGIAAIQQASTMEELKAIKAKYAGANSAMTRASKAIGSLAKNEKKEAGKVMGKLRADFGRAYGTKEASVKAAQEAAELAAETVDMTLPIRRKPLGARHPLPKLMEDVEDFFVGMGWQISDGPEVETEWFDFDALNFGPDHPARQMQDTFYVKGNQSKDAAGFVGSNMVLRTQTSSDQVRGLISHGVPLYIACPGRVFRTDELDATHTPVFHQVEALAVDKNLTMADLKGVLDKLAVAMFGPEAKSRLRPSYFPFTEPSAELDLWFPDKKGGPGWIEWGGCGMVNPNVLRSAGIDPDIYTGFAFGVGVERTLLLRHDINDMHDLVEGDVRFSEQFVMGE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3K01_CYRHA
Sequence: MKASMFLALAGLVLLFVVGYASESEEKEFPRELLSKIFAVDDFKGEERGCKGFGDSCTPGKNECCPNYACSSKHKWCKVLLGK
What is the function of this protein?
Lethal neurotoxin.  Selectively blocks tetrodotoxin-sensitive voltage-gated sodium channels (Nav).  Does not affect tetrodotoxin-resistant voltage-gated sodium channels or calcium channels (By similarity).
What are the official names of this protein?
Mu-theraphotoxin-Hhn2d, Mu-TRTX-Hhn2d, Hainantoxin-III-11, HNTX-III-11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_PANGI
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MUTS_PECCP
Sequence: MKDSTDKDFTAHTPMMQQYFRLKAEHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGVPHHAVENYLARLVQMGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQEKQDNLLAAIWQDSRGFGYATLDISSGRFRVSEPTDRETMAAELQRTNPAELLYPESFESMDLIENRHGLRRRPLWEFEPDTARQQLNLQFGTRDLTGFGVEQAKLALRAAGCLLQYAKDTQRTSLPHIRGITMERQQDGIIMDAATRRNLELTQNLSGGVENTLAAVLDCTVTAMGSRMLKRWIHMPSRDIDALQQRQQAISALQDITPDLQPYLRQVGDLERILARLALRTARPRDLARMRHAFQQFPDIREQLAPLDIDSVRRLVSLIGQFDELRDLLERAVIEAPPVLVRDGGVIAPGYNAELDEWRALADGASDYLDRLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKALYDELFDLLLPHLAELQQSAAALAELDVLTNLAERADTLNYVCPTLSDKPGIKITGGRHPVVEQVLREPFISNPLSLSPQRRMLIITGPNMGGKSTYMRQAALIVLMAHIGCFVPADQAVIGPVDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANRIKAMTLFATHYFELTTLPEKMEGVVNVHLDAREHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLKELEMLSNNASSSHIDGAQLALLGNDEPSPAIEALEAIDPDALTPRQALDWLYQLKKML
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SELO_PSEAE
Sequence: MKSLDDLDFDNRFARLGGAFSTEVLPDPIAEPRLVVASPAALALLDLPAETSDEALFAELFGGHKLWSEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVINQAGEHWDLHLKGAGQTPYSRMGDGRAVLRSSIREFLASEALPALGIPSSRALCVIGSSTPVWREKKESAATLLRLAPSHVRFGHFEYFYYTRQHDQLKQLAAFVLEHHFADCNAAERPYAAMFRQVVERNAELIARWQAYGFCHGVMNTDNMSILGITFDYGPYAFLDDFDANHICNHSDDAGRYSFSNQVPIAHWNLAALAQALTPLVEVDELRASLDLFLPLYQAHYLDLMRRRLGLGVAAENDHALVQELLQRMQGSAVDYSLFFRRLGEETPERALASLRDDFVDREAFDRWAEAYRRRVEEEGGDQESRRRRMHAVNPLYVLRNYLAQQAIEAAEQGDYTEVRLLHQVLSRPFEEQPGMERFTRRPPDWGRHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: METK_FRATF
Sequence: MSKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTSAWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDIAQGVDRGSLEDLGAGDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDKPKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYRKTSNYGHFGRELPEFTWEKIDKADILKSAARI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRP2
Sequence: MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVELEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STRZJ
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHLRKASMVHSGDYKRIKAMLTRLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: VE6_HPV51
Sequence: MFEDKRERPRTLHELCEALNVSMHNIQVVCVYCKKELCRADVYNVAFTEIKIVYRDNNPYAVCKQCLLFYSKIREYRRYSRSVYGTTLEAITKKSLYDLSIRCHRCQRPLGPEEKQKLVDEKKRFHEIAGRWTGQCANCWQRTRQRNETQV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation.  In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development.  The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).  The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization.  Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis.  E6 also inhibits immune response by interacting with host IRF3 and TYK2.  These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: FBPC_MANSM
Sequence: MTNQNDNFLVLKNINKTFGKSVVIDDLDLVIKRGTMVTLLGPSGCGKTTILRLVAGLENPTSGQIFIDGEDVTKSSIQNRDICIVFQSYALFPHMSIGDNVGYGLRMQNIAKEERKQRIREALELVDLAGFEDRFVDQISGGQQQRVALARALVLKPKVLLFDEPLSNLDANLRRSMREKIRELQQSLSITSLYVTHDQTEAFAVSDEVIVMNKGKIVQKAPAKELYQQPNSLFLANFMGESSIFNGQLQGNQVTLNGYQFTLPNAQQFNLPNGDCLVGIRPEAVTLKETGEPSQQCSIKTAVYMGNHWEIVADWAGQDLLINANPEVFNPEQKQAYVHLSSHGVFLLKKE
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECA_BURTA
Sequence: MTTGFLQKIFGSRNQRLVKQYQKTVATINALETQIEKLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDARVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNGEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECYERGQPVLVGTTSIENSELLSHLLKQAGLPHEVLNAKQHAREAAIVAEAGRPKRVTIATNMAGRGTDIVLGGNVEKQAAFIEADEAIPADEKARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETLRNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAASAGGAVVADATAEMVGHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DEF_BACTN
Sequence: MILPIYVYGQPVLRKVAEDITPEYPNLKELIANMFETMVHADGVGLAAPQIGLPIRVVTITLDPLSEDYPEFKDFNKAYINPHIIEVGGEEVSMEEGCLSLPGIHESVKRGNKIRVKYMDENFVEHDEVVEGYLARVMQHEFDHLDGKMFIDHLSPLRKQMIRGKLNTMLKGKARSSYKMKQVK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL32_PSYCK
Sequence: MAVQKSRKSRSRRDMRRSHHRMEIAEISVDATTGEKHRRHHMTKDGFYRGRQLFKVSQDA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TAUB_SHIFL
Sequence: MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSDGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLRLNFARRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPAT_GLOVI
Sequence: MKTAARLDRIPPYLFAEIDRRRDEAVARGVDIINMGIGDPDKPTPPVVLEAMHAAIDDPSTHNYPPYKGTKAYREAAAAWFERRFGVGGFHPDTEVISSIGSKEAIHNTFLAFVDPGDYTLIPDPAYPVYRTSTIFAGGEFFAMPLLPENQLLPDLEAVPETVARKAKLLWLNYPNNPTGAVASLEFFEKVVHFAKKHDILVCHDNAYSEMAYDGYKPPSILQVPGARDVAIEFLSCSKAYNMTGWRVGFVIGNRTGIAGLGQVKTNIDSGVFKAIQQAAIAAFGLDDERLHALMAVYQNRRNIIVEGLRSLGWPLEAPKATLYVWAPIPKSFGSSVEFVGALLDKCGIIVPPGNGYGEHGEGFFRIALTVPDERMREAIGRMEAAGIRFEG
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.  Can also use m-DAP instead of LL-DAP as the amino-group donor.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: SERC5_DANRE
Sequence: MCTPCCVSQLACCCGSAACSLCCGCCPKIKQSTSTRFMYALFFMLVTVTCVIMMSPTVEMAMREHIPFYSQMCQQLNAGENCSTLVGYSAVYKVCFGMACFFFFFAVFTIRVQNSTGCRAAVHNGFWFFKFVALLACCAGGFFLPNQDQFLEVWRYVGAAGGFLFIIIQLMLLVQFAHRWNQNWSSGATYNKLWYAALALVTLVLFSVAVGGMVFMFMYYTHPEACFLNKIFLGVNGGLCFIVSLLAISPCIQTFQPTSGLLQPAVITLYVMYLTFSALASKPIEMVEDEIKGNITVCVFPFKSGLKSDTNIVTGVGTAILFCCILYSCLISTTKRSSAALQVYRNDMPENERARCCFCWVDDTEDYDDEKTSGGQNVKYDERDGTVYSYCFFHFVFFLGSLYVMMTVTNWFHYDNAKIERLLEGSWSVFWIKMASSWVCLFFYMWTLVVPMLFPQRFQA
What is the function of this protein?
Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (By similarity).  Enhances the incorporation of serine into phosphatidylserine and sphingolipids (By similarity).
What are the official names of this protein?
Serine incorporator 5.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane, where it is efficiently incorporated into budding gammaretrovirus virions and impairs subsequent virion penetration of susceptible target cells.
Protein: CB39L_HUMAN
Sequence: MKKMPLFSKSHKNPAEIVKILKDNLAILEKQDKKTDKASEEVSKSLQAMKEILCGTNEKEPPTEAVAQLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRSPTVEYISAHPHILFMLLKGYEAPQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHKVLVADFLEQNYDTIFEDYEKLLQSENYVTKRQSLKLLGELILDRHNFAIMTKYISKPENLKLMMNLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNYLIKQIRDLKKTAP
What is the function of this protein?
Component of a complex that binds and activates STK11/LKB1.  In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).
What are the official names of this protein?
Calcium-binding protein 39-like, Antigen MLAA-34, MO25beta, Mo25-like protein.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: ASTE_PSEP1
Sequence: MLALGKLLELTLTAHEPAEKTQVTPGGARLRWLGEGALEVRPAESEDCGLDLLLSAGIHGNETAPIELLERLLHGVANGKIKPRARVLFLFGNPAAIRKGERFIEQDINRLFNGRHELSSGFEALRAAELEQFARVFFSKPGRNRLHYDLHTAIRGSKIEQFALYPYKEGRKHSRRELARLAAAGMEAVLLQSKSSITFSAFTYEQLEAEAFTLELGKARPFGQNEQVNLDKLEERLIRIIEATEPENESSLDGLQLFSVSREIIKHSDSFHLHLPADIENFSELSKGYLLAEDLAEMRWVVEEEGARIIFPNPKVKNGLRAGILIVPDSGQRLG
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.