PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_ECOLU
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YJGA_ECOK1
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: Y934_STAEQ
Sequence: MPIINVKLLEGRSDEQLKDLVTEVTHAVEKTTGANKEAIHVVIEEMRKDHYAVGGVRKSDQ
What are the official names of this protein?
Probable tautomerase SERP0934.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: NU6M_MARPO
Sequence: MILFYVFVVLALVSGAMVIRAKNPVHSVLFLILVFCNTSGLLVLLGLDFFAMIFLVVYVGAIAVLFLFVVMMLHIRIEEIHENVLRYLPVGGIIGLIFLLEIFLMVDNDYIPILPTKLSATYLTYTVYAGKIHSWTNLETLGNLLYTTYFFLFLVSSLILLVALIGAIVLTMHKTTKVKRQDVFIQNAIDFQNTIKKVR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: AFFL_DROVI
Sequence: MAQQQQQQHQQQQHHQQQQQQLQQQQQLLQYNNNSYNLNYNMEDPERRKRREREKYERQQGIQSDDRETSLFGEPRRLNPNEGDPEITAALGDFVDARDYMNASTVGIYRQAPGASNARLQALPKGFGSATTSFSSSSSASASSSASVPGQLPTSQQQQQQQQQQQQQHYQQQQRAPTYLKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRSSSSSSSSNNNSSSVSNNATAAPTSASTSSPLGPPMSTQMPNGREKSFLGPPAPALPNGGRFVPPSASGKRPSSTAGLQPPPPENHINKIITEMTNNYRVTPLTSIAATPHAPMRENYNLNGPNKFKYAFDAVDPIGPLNSPPAAGASSLMTPLLAPIAPITSPIAPLLTTPPQASQLPLPLPPMAGATTVPPSMAMGAVAPMQQLTPTPPKASPTPPVIKPLKTEKNHSLEKQDSCLENDLELSESDDERKKDSRSAGNSSNSSESDSSESGSEASSKGDPQQQQQQQQQHLLHQQQQHQQQQLLLQQQQQQRLAATANGSKKKYSQTIIASGANTISGLLTSSGLGGTGAGPGGAVNSTGSAAGGVGSGSGSTGGGSSSSGMGTMSSSNSSNKTPSPTDSNRWHLSRFFPKPANQTAAESVSPGVANAMGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKLHDDSRHMDDDEDEQADQQHQQQQQRYGVGLSVTVKKEQLEQQQQQQQQQQLLLQQQQLTAEQLALAGALPKNQIKRESRLSDSGSGSSGSGSSSSDSAGGSSEVLPMPGPGETLQIPGVPAAITTVMRVPPATQHKAQPNSVTLTPIGPLPASPKPRQKKPRKKKMSAATAPPLDSSDEDEPANSNKKHALELAATAAAAAANAAAASVMPVAAAAAAAAAPAIKKGRGRPRKQAQQQQQQLQLQQQQQQSGNLSSASASSSQAKGPTLTAAKKPLAKGTASSSSSSGTAATVAAGSRKREHSSNSSSNGNTPTKKPNAAMAAAAAAAAAAAAAAIAVRAASSSDEDSSSSSCSSTKSSNSNSSSSGSDTDIPTAAPAVTTAAAVAAAAAQNPAKKRIVKINKVGVASSKAKRRFSLGNSSNSSSSETEEQQQQFLQQQQQQQQQKQQLQQQQQQQPQQQQLQQHHQLQQQQQQQLLQGHFAPELPLQTLKQSAQQRLSSSDCSSSASSDSSSNSSASSSSDEDDAHRSGKRKSDKKKICTLTRIFNPKEGGAKKQGQVVIIDQSEEQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQAKELKPRATPTQLLGATLASPARTTTPHLTSLMCKIDLSKLARQHHHQPERLKTQQNGHLSSRSAEGARTPKELQQIYAPNGYVGGALGGAAGAAAGNKLLGGVKHEHGVKPEPELDAGYEAKYKPNSVKQEFMLKQELPARRRKRSSSSSSSPYKEKKRKKEKAEQLSKELLPVPVLLPANNHERLSRDKLELLLQQQENSANASPNKLQQQNARQLPLSQSQLQHQHQHQHQLQQQQSQSTATGHAIASTTSATVATASTQLPTTCSEAVQTTPPPAAPPPAPRLIYRSHFDNEEEHASDDHRKNDLLLQEAIRRKRAADSERDSFNQMTLYLEAIVYFLLTADAMERCNMEATWTMYKDTLSLIKYISSKNRPYQQLTNGKHESHNIVAILSLRCQSLISLKLYKLRRANCRATIASCSEFFRSGRGDILNGNTPSSISPSNSVGSQGSGSNTPPGKIVPQDIHNQLCKQNEYLTYVNSAHELWDQADRLVRTGNHIDFIRKLDHENGPLTLHSTMHEVFRYVQAGLKTLRDAVSYPQSQ
What is the function of this protein?
Has a role in transcriptional regulation.  Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth.  Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate.  Required specifically for the microtubule-based basal transport of lipid droplets.  Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye.  Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation (By similarity).
What are the official names of this protein?
AF4/FMR2 family member lilli, Protein lilliputian.
What is the protein family that this protein belongs to?
Belongs to the AF4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIGB_SALSV
Sequence: MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEIARLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLARAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTKKYTLAVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPAAQYWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASATCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFEHIFSWLALTSAQIANTPGFAKGKSEQIWRQFNLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWRQLPATGERRAGRVIDWRDNPQIKALSRWLSAQHIPGFGS
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: LSY27_CAEEL
Sequence: MTSIHSPVTRKEDTELKRPDLRGKFVCSSCSQNFQHSASLNRHRQLMHSNEHTCMMCERALNQKETIREHMRNEHNLAQVFTCGCCNWTFASKRQLTEHTKCIQGTGAPGDTIPIAKSINAPGSLIQSTIQGTPPVVKTGRKRPMGGSLSPSSSVSTSISSRDASGSPPPTEEEAERKVLFDNAVDTILQSKFFTYQQITEVDTWVKIIESANTLADTLQRIKKSQKVKAEGPAVESKMIPEKHVKQEIE
What is the function of this protein?
Involved in regulating left/right asymmetric differentiation of the gustatory ASE neurons (PubMed:21555395).  Plays a role in modulating expression of LIM/homeobox protein lim-6 (PubMed:21555395).
What are the official names of this protein?
Zinc finger protein lsy-27.
Protein: RIMM_SYNR3
Sequence: MADEFLVVGQVVAAQGLKGEVRILPASDFPQRFTEPGSRWLRRRGHNEQQVQLLSGRQLPGKELFVVRFEGINDRTAAESLVHQEFLVAADDIPELEDGEFHVRDLQGLSVRLDTESDPIGVVVDLHHGGNDLLEIELKADGRRCLVPFVDAIVPQVELEEGWLLITPPKGLLDG
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNC37_CAEEL
Sequence: MKASYLETLDRIKDEHAEMSKHVNQQRSDIEKVALEKENMNRSYMTYAEVSNTLRSDLRKAEEINKRLQEFIMQSLAPQLSQDNQANCLAALEAFKTASPRENGNGAPALPPGFPPGAAGMLGMMPNMPFGMSPAMSQLFNQFASPHVNGGDGAGGSSGGASEAKKAKLEDPDDGELEIDVTNDDHPSTASNGGAANKNGRDSTNSVASSGASTPSIASNSRARQQQQPLAGLQGLEQMNFLAGFNPNLLRQASAAGGFNFLNDPHAQARLAAAIGQIGSRPAYSFKIVDGGVPTPTSFPPDAQKGPGIPTGLKKKMELNHGEVVCAATISRDNSRVYTGGKGCVKIWDVKESDISGATVVNRPPIASLDCLKENYIRSCKLFEDGNTLLIGGEASTVALWDLTTETKTLDLETDSQACYALAMSPDEKLLFACLADGNILIYDIHNKVKVGTLPGHQDGASCLDLSKDGTKLWSGGLDNSVRCWDLAQRKEVAKHDFASQVFSLGCCPNDEWVAVGMENNYVEVLSTTGKEKYQLTQHESCVLSLKFAHSGKFFISTGKDNALNAWRTPYGASLFQLKENSSVLSCDISFDDSLIVTGSGEKKATLYAVEY
What is the function of this protein?
Transcriptional corepressor that functions with the neural specificity gene unc-4 to govern motor neuron identity (PubMed:9165118, PubMed:10557206, PubMed:17289921).  In concert with unc-4, represses the expression of VB-specific genes such as ceh-12, thereby preventing the adoption of VB motor neuron fate (PubMed:10557206, PubMed:17289921).  May function with transcription factor mls-1 to promote uterine muscle specification and formation (PubMed:21852953).
What are the official names of this protein?
Transcription factor unc-37, Uncoordinated protein 37.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYSY_MALP2
Sequence: MKEYKDLLKLVLDNGIMQENRTDTDAIAYFGTQSRYDLTKGFPLLTTKKMAYKAIFHELLWFLKGETNIKYLVDNNVKIWNEWPYENYKKSPYFKNESIDEFILKIKEDDSFAKQFGELGPVYGRQWRNFNGVDQITNLIEEIKKNKYSRRLIVSVWNPSEIKNMLLPPCHCLFQFFVNSKNELSCQLYQRSADLFLGVPFNIASYSLLTYMIAQVTNTTAKEFVHTIGVAHIYNNHIDQVKEQLTREPLQLPTLVLNKNIKNIFDFKIEDIEIKDYNSHPAIKGKVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_LEPBY
Sequence: MQLQYFLLIAAALFCIGVYGLVTSRNAVRVLMSIELMLNAVNLNLMAFSNYLDPQEIKGQMFTIFVITIAAAEAAVGLAIVLAIYRNRDTVDMEQFNLLKW
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L, NDH-1, subunit 4L, NDH-E.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: EF2_DEBHA
Sequence: MVAFTIEQIRELMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYASMTDDDCKEIQQKTVGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVEGVCVQTETVLRQALGERIKPVVIINKVDRALLELQVTKEDLYQSFSRTIESVNVIISTYVDSSLGDSQVYPDKGTVAFGSGLHGWAFTVRQFATRYSKKFGVDRIKMMERLWGDSYFNPKTKKWTNKDKDAEGKTLERAFNMFVLDPIFRLFSSIMNFKKSEIPTLLEKLEINLKAEEKELEGKALLKVVMRKFLPAADALLEMIVIHLPSPVTAQAYRAETLYEGPADDASCIAIKNCDPTADLMVYISKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYQVGKKDDLFVKAIQRTVLMMGRFVEAIDDCPAGNIVGLVGVDQFLLKSGTITTNEASHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTSMSESGEHIVAATGELHLEICLSDLQNDHAGIPLKISPPIVSYRETVNAESSMVALSKSPNKHNRIYVKAQPIDEEVSLDIEKGVINPRDDFKARARILADNHGWDVTDARKIWCFGPDGNGPNLVVDQTKAVQYLNEIKDSVVAAFQWATKEGPIFGENVRSVRVNILDVTLHADAIHRGGGQIIPTMRRVTYASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVISEEQRPGTPLFTVKAYLPVNESFGFSGELRQSTGGQAFPQLIFDHWANLNGDPTDPTSKVGTIVKEKRERQGMKPDVPGYEEYYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXS_BURCJ
Sequence: MESIGIVAPQTMHFAEPLRLQSGSVIGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVYADDPRSTGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSIDPSTGKPYGAKFPVVTVEDWVHAQARVADAFGIERFAAVMGGSLGGMQALAWSLMYPERVAHCIDIASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHGVKPKRGLRVARMIGHITYLSDDDMAEKFGRALRRADGALDAYNFSFDVEFEVESYLRYQGDKFADYFDANTYLLITRALDYFDPAKAFDGNLTAALAHTQAKYLIASFSTDWRFAPARSREIVKALLDNKRTVSYAEIDAPHGHDAFLLDDARYHNLIRAYYERIANEVGA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPL4_PICST
Sequence: MSVTLRFRSREGTFRVAANPDADFLLVLEQLLSKISIEDVQNLYLSDKPNSKGELANGLCGKTVTELGLKNGDMLYASYEAATGSNPDSTTNITTSTNNHNSGSISIGHISIPTTTSGPRKVTQLPVDDVLEKDEGLIKRPLTKFCRHGAKGMCEFCSPLPPWDANYRKENAIKHMSYHAYLKELNELKNSKHNSSSYIAPLEEPNYSILLNCNEGHQPYPKGICSKCQPPPITLQLQKFRMVDHVEFATSSIMNNFIDVWRHTGVQRFGVMYGRYEPFDKVPLGIKAVVEAIYEPPQSGELDGITMLPWENEAEVDAIASELGIYKVGVVFTDLTDSGQKNGTVLCKRHKDSYFLSNLEILMAARNQIQHANITKFSSSGQFSSKFVTCVISGGLNGEIEPRSYQVSTSAEALVRADIITGSTQPSRLYVNSSNDRRYVPDVAYSELNEYGLEVKSNAKPTFPVDFLLVSLTDSFPVNPTPMFDTDSNFVIENRDFFNELQNLHAVSKYLNADTSGKGTSLCNFHFLVYLKRTNILGAQEFDLLLRFVRERQYEDYLHLVESPGWMTLITILEQST
What is the function of this protein?
Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus.  Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
What are the official names of this protein?
Nuclear protein localization protein 4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes mainly at the nuclear periphery and the endoplasmic reticulum membrane.
Protein: IGMDE_STRSE
Sequence: MNIQERFSLRKSAVGLVSVSLLCAIYTSTVAADTVVTGVNEIIEESQVKDEVSIESEKNESLDGSNIEIVEEIADNIPSPVIAEGEVAVEMKVDRGTENVVSRNDTEVTTSEQNQIEVTETKEILNQTSYQTESGEQRQIIWAHGITPPAMEQSGGFVKEKYGDYLNYTAPFEAGKGYYDTNKSLNASFIDLNLCFAAVSSNMVHWWLEQNSSYVERYLKEKKGTVNVEENYAITDLRRYINSFQNQQNSRVFDMFKTYYGYRTNGFVSDALVDLFINGYKPKAQGGVNLEDSQLVPDSRGGFFYDVFKEKKLTNRIFSGSYERFGEDVRTVLESKGLLGLTYRTLGYATHIVTVWGAEYDNQGKIKAVYITDSDDQQEQIGLKRMGITRDASGNPRLNNHMKNNSAGALLDYVHTIRLGQDLWEEYFNPLAKAKETASQTLADTKKALDLSIQGQSELPESMRLIYLEKLNNLYNQGILSIQKAESSEMLSGALENGLNSLKSLDFPISEVGNALAPDLPVGDRSTVSDVDSLSSQETSSTNLEADTENAGIIADGTNQLHFPVEAQTTSSVEAEGDNVFEQEADTLPIIIENKDEFGSELSRNMQTSETDSLVVAVEEDVKNDEVAQVEELLESEKVENQSSELLSDTLIVESANDKEEDRVEAVVSEQPDSIPHQNVEISLVEPTNVETETVVTPINDAATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPTSSESTNVETETVVTPVNDVATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPTSSESTNVETETVVTPVNDVATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPTSSESTSVEAELVDNSEIHAATSSVTPCGSSAYADGSTTESVATPLEKDSIQTGNTEIAEPTSSKSTNVEAASVDNSEIHADASLTAVSSVNLDNPVIEPVAISLIGSKRDTNAEVEVSSLSKREVRKTNTDGLISVQSKVIKKELLESSLAEAGSPLLEATIAQSSNSNSTEIGMSYQNTVLLESNNTERQVSKAEIVMEHKETELVETVSSASEPVVLVENISQTSNNTIESGKNMGVQSQAGAKQILGVEQSSKVSTPTSRQIMGVGLLTLVLGSALGLLKKRRK
What is the function of this protein?
Catalyzes the specific cleavage of porcine IgM bound to the bacterial surface.  Can degrade only IgM but neither IgG nor IgA, and is host specific, as it exclusively cleaves porcine IgM but not IgM from six other species, including human, mouse and a closely related member of the Suidae family.  Promotes survival in porcine blood.  Is thus involved in a so-far-unknown mechanism of host-pathogen interaction at an early stage of the host immune response.
What are the official names of this protein?
IgM protease, Immunoglobulin M-degrading enzyme of S.suis, IdeSsuis.
What is the protein family that this protein belongs to?
Belongs to the peptidase C66 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted. Note=Is released into the extracellular space and remains at least transiently attached to the bacterial surface, likely via its C-terminal transmembrane domain.
Protein: UNG_HELPS
Sequence: MKLFDCAPLSLAWREFLQSEFKKPYFLEIEKRYLEALKSPKTIFPKSSNLFYALNLTPPSAVKIILLGQDPYHSTYLKNQQELPVAMGLSFSVGKNAPIPPSLKNIFKELHANLGVSVPCCGDLSAWAKRGMLLLNAILSVEKNQAASHKRIGWEAFSDQILMRLFEANAPLIVVLLGKIAQKKIALIPKNKHIIITAPHPSPLSRGFLGSGVFTSIQNAHREIYHKDFDFSL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_RUBXD
Sequence: MRLTPELLVECYRRGLFPMAGPGGRVGLYRSDPRAVLELDALHVSKSLARVLRKGVYEVRIDQDFEAVIRACADREETWISEEIIRAFLGLHRRGLAHSVEAYDGEGRLAGGLYGVALGGAFFGESMFSRRPDASKVCLVRLVERLRERGYVLLDCQVQSPHLERMGAVEIPEAEFMRRLSEALRLDRAFA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4JF_SINFN
Sequence: MALANFIDRAATAASQVLTDFHLGDFKAALEKQVVAVAFDDQAASCAEGQATLDLAVRLLARLYPVLAILPLDSASSFQAQALERLAKSINPKIGIRRSGKSAMVCLVAGATRPSLRCTTFFIGSDGWAAKLSRTDPVGSGSSLLPYGAGAASCFGAANVFRTIFAAQLTGAELDPDIDLSLYSYNKTKARDARPVDLPVDLGETHLVGLGAIGHGALWALARQSGLSGRLHVVDHEAVELSNLQRYVLAGQAEIGMSKAVLATTALRSTALEVEAHPLKWAEHVARRGDWIFDRVGVALDTAADRLAVQGALPRWIANAWTQEHDLGISRHGFDDGQACLCCMYMPSGKSKDEHQLIAEELGIPETHEQVKALLQTNAGVPNDFVVRVATAMGVPFEPLAPFVGQPLRSFYQQAICGGLVFQLSDGSRLVRTVVPMAFQSALAGIMLAAELVKHSAGFPMSPTTSTRVNLLRPLGSHLHDPKAKDSSGRCICSDEDFISAYRRKYGNSVEPLSNISAT
What are the official names of this protein?
Uncharacterized protein y4jF.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCIB_SALPC
Sequence: MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRYRKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQRMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGVYIYRHLPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FDHE_ECOUT
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESG2_TRYBB
Sequence: MKVEIVELVVLLFSVTCVDAWLQGADCTRVADHKEHAPVTEAVCYLRCLSDALNKLYSEGEKKLLVTEEVYANASLILDDMEGRAGESSTYLSVIRGVMEEQTDRLEKLISYGNKMGNLVAKAGGLFAALEDSLKEVRKEIPGALIKTNKYYTSVAEIVRTVWEDVGEILWKETEAKCGSQKVEGVGEIQTECGAHTCPFADNGVAASAVDKYKGHCLYVGRNSYLRHCFNLPRGRLYRHGPVNTLGDALEWEENWSDYMNFELTVKVQKIFGPLIASFDVGIAPSTLAEMINNITSLQSRFNEVHSNFTSILFTTKLKTEVYNTDSTI
What is the function of this protein?
Not known but may be related to activation of the variant surface glycoprotein genes.
What are the official names of this protein?
VSG expression site-associated protein 221A, ESAG protein.
Protein: RIMP_METCA
Sequence: MRMPEHLQRLIEPVVTGLGYELAGIEFDARARVLRVYIDHPQGIGLDDCSKVSYQLSGMLDVEDPIPGQYQLEISSPGLDRPLFTLEHFKRFTGRRVRLQTLRSLDGQRRFKGEIAGVRGDVIDLEDDNGLHAIPFDLIDKARLIPEFDI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL016_HUMAN
Sequence: MLKKPSSLEQWEILGTSSGEFRCISRDCPGAGNNNREPSISTRGRTSSSKMVLPHPKVAEEAVGGPQSCKWLSCGLQGTGGGHLEGHPPRVSQESAPAGHTGISPSSSGVHLIQAKTAGWPQRVSSAEQCLLPIQHVPGADFLHVFTLRLHCGPARNAKLVEALFNSNSSC
What are the official names of this protein?
Putative uncharacterized protein LOC100128554.
Protein: RL2_METLZ
Sequence: MGHRISTQSRGKGGPTYRAPSHQYKAELKHFGSALETVRATVIDIEHDPARHTPIAVVKIEGKASDKKEYALITEGVGIGQELVWGPEATVVNGNSLPLSAIPTGVAVCNIEARPGDGGKFVRSSGVQAVIIGKSAGKVGVRMPSGKPKWFNEACLATVGLVAGGGRIDKPILKAGKQYHKMKTSATRWPRVRGVAMNVIDHPFGGGGHQHPGKPKTVARGASPGRKVGSVAARRTGYRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: EFTU_BRELN
Sequence: MAKASFERTKPHVNIGTIGHVDHGKTTLTAAITKVLADQYPDLNEARAFDQVDNAPEEKERGITINVSHVEYQTEKRHYAHVDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYIVVALNKSDMVDDEELLELVEFEVRDLLSSQDFDGDNAPVIPVSALKALEGDEKWVKSVQDLMAAVDDNVPEPERDVDKPFLMPVEDVFTITGRGTVVTGRVERGVLLPNDEIEIVGIKEKSSKTTVTAIEMFRKTLPDARAGENVGLLLRGTKREDVERGQVIVKPGSITPHTKFEAQVYILSKDEGGRHNPFYSNYRPQFYFRTTDVTGVITLPEGTEMVMPGDNTDMSVELIQPIAMEDRLRFAIREGGRTVGAGRVTKITA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.