PharMolix/UniProtQA huggingface dataset:
Protein: SYY_SYMTH
Sequence: MTMAFMSVDEQMKILMRGVVDLVSEEELRQKLERSVKTGRPLRVKLGIDPTGKDLTLGHTVPLRKLRDFVECGHQGVLIIGDYTAMVGDPTGRNEARPQLTHAETTANAQRYLEQAARVLDVSKLEIRRNSEWLAPMSFSDVIRLAAKSTVARMLEREDFKKRYEEGRPIFIHEFFYPLMQGTDSVAVQADVELGGTDQKFNLLAGRDLQRDAGQEPQVCLMTPIVEGLDGVQKMSKSLGNYIGLDHTPDEMFGRTMSIPDSLIITYFTYFTDVPQEEIERIEAAMAAGENPMTFKKQLGRAIITTYGGTEEEARLAEERWVAQFSRGEVPEDIPDVVLPAAELPMQAARVLFTAGLAPSLSEARRLIEQGGFTVDGEKVTDPRAELALRPGQVLKAGKRKYGRVVLK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH6B_HUMAN
Sequence: MSWTVPVVRASQRVSSVGANFLCLGMALCPRQATRIPLNGTWLFTPVSKMATVKSELIERFTSEKPVHHSKVSIIGTGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCSKDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSNPVDILTYVAWKLSAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHGDSSVPVWSGVNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAYEIIKMKGYTSWAIGLSVADLTESILKNLRRIHPVSTIIKGLYGIDEEVFLSIPCILGENGITNLIKIKLTPEEEAHLKKSAKTLWEIQNKLKL
What are the official names of this protein?
L-lactate dehydrogenase A-like 6B.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: EFTS_EHRCJ
Sequence: MKIDISAIKKLRDLTGAGVGDCKEALSSCDGDIEKAKNYLREQGIAKAYKKSTKDVSDGLIAIHVDGNKGAILEVNSETDFVARNEKFQKLVLNLVSLANQYATESIEDFLKHEYISGTSVHDEIMSNIAIIGENIHLNKIGCLSVNSGVVSGYIHNPVIDNLGKIGAIVALESNGDSEKLKVLAKQIAMHIVAAKPEALSLDVLDKDLLNKEREIIKKQVDQLNKPAAVAEKIIDGRMAKFYQDVVLLDQVFVMDSQLTISELVKRKESELAETINLIGYKLFVINK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MELT_MOUSE
Sequence: MHQLFRLVLGQKDLSKAGDLFSLDDAEIEDSLTEALEQIKVISSSLDYQTNNNDQAVVEICITRITTAIRETESIEKHARALVGLWDSCLEHNLRPAGKDEDTPHAKIASDIMSCILQNYNRTPVMVLAVPIAVKFLHRGSKELCRNMSNYLSLAAITKADLLADHTEGIIKSILQGNAMLLRVLPAVYEKQPQPINRHLAELLALMSQLEQTEQYHLLRLLHVAAKRKDVEVVQKCVPFLIRNLKDSTYNDIILNILIEIAGHEPLALNSFLPMLKEIAEQFPYLTGQMARIFGAVGHVDEERARSCLRYLVSQLANMEHPFHHILLLEIKSITDAFSSILGPHSRDIFRMSNSFTNIAKLLSRQLENSKADSSRRKTSTEVSIPEKLRELNSMEPESEDHEKLQVKIQAFEDKINAESNTPGSGRRYSLDHISKEERKSIRFSRSRSLALNTVLTNGVSVEDNEVEEKAGMHASISLSQIDPLSHGIGKLPFKTDTHGSPLRNSSASHPSIIHTEPETMPETFKENIQEEILEAATSPIEYQDKLYLHLRENLSKVKAYALEIAKKVPIPDQCTIEDTMRSCVAKLFFTCSLKGHYCLYSKSSFILVSQAPQPWIQVMFLSQQSLFPEPLSIQSGSVQFLKALWEKTQDTGAHSFEVAMTESTFPQQKDLEQLQLHLEEVRFFDVFGFSETAGAWQCFMCNNPEKATVVNQDGQPLIEGKLKEKQVRWKFIKRWKTHYFTLAGNQLLFQKGKSKDDPDDSPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDSKTYVFKAKDEKNAEEWLQCINVALAQAKERESREVTTYL
What is the function of this protein?
Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling.  May also affect FOXO, Hippo and Wnt signaling.
What are the official names of this protein?
Ventricular zone-expressed PH domain-containing protein 1, Protein melted homolog.
What is the protein family that this protein belongs to?
Belongs to the MELT/VEPH family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MRAY_LACDB
Sequence: MQASLIAFMISLVLSALLFPWLIIWMRSHDEGQQIRDEGPKWHEKKSGTPTMGGTVFVLSAAVATVAICAYKGQLSKTVWILLVALLGYGIIGFLDDGLKLFFKRNLGLRAWQKMDLQLLVAAGIVLLAASDNFDFALYLPFAGVVKNVVLFTLFEVFWLVGFSNAVNLSDGLDGLATGLSFIAYGTYAWLAFKSQNFGVLVFCMAVMGGLAAFFMFNHKPAKIFMGDAGSLALGGGLAAVSIFLGRPWSLLLVGIVFVCETASVILQVASFKTTGKRIFKMTPIHHHFEMLGWSEWKVDLVFWLVGLVGSGIYLMIWG
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_EXISA
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQKTVKKVDEAYNFVRELAAEGGNVLFVGTKKQAQDTIKEEAIRSGMFFINERWLGGTLTNFSTIKKRINRLKQLEKMEEDGTFEVLPKKEVIILKKEMTRLEKFLGGIKDMPGVPDALFIVDPRKERIAIAEAHKLNIPIVAIVDTNCDPDEIDYVIPANDDAIRAVKLLTSKMADAIIEAKQGEEEVAEEAVATEAEATEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ATPE_BRUAB
Sequence: MAQAFQFELVSPERLLLSAQVTEVVIPGSEGYLTALAGHSPLMTTIMPGVVSVKLADGKTDSYVVFGGFADITPQGCTVLAESATHVDDIDPADIQHRIDHARKVLEDASSNEHRTKAEIFLHQLMTLQGAILPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNC_TREPA
Sequence: MSLCLGHIFSRSRSPLTPERRESLRRLQETLGVKFRDPTALDQALSHRSLFSSKEDHCGVRHNERMEFLGDAVLGAVAAACLYRALPDSHEGDLAKTKAVLVSTDTLSDIALSLRIDHYLLLGKGEELSGGRHKKAILADATEAVIGALFLDSGFKAAERFVLRLLLPRVRPIREKNLHHDYKSTLQVLAHQRYRSKPEYTVVKRTGPDHSVRFWVDVTVGDARFGPGYGTSKKSAEQCAARLAWEQLSGTLRE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTOR2_DROME
Sequence: MLKPKALTQVLSQANTGGVENTLLLSQEGALLAYSGYGDKDARITAAIASNIWAAYEKHGRNAFREGRLTFVLIDCENGHVAITQVASVLLCLYAKQTVGLGLLKQKAMSLASYLERPLKQISAS
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids.
What are the official names of this protein?
Ragulator complex protein LAMTOR2 homolog, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2.
What is the protein family that this protein belongs to?
Belongs to the GAMAD family.
Protein: ATPB_OCEIH
Sequence: MSKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSSTDGFKRGAEVENLGRPISVPVGDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFENLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAIYVPADDYTDPAPATTFAHLDATTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEVATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRIQFFLSQNFHVAEQFTGQPGSYVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MATK_ASPEL
Sequence: MEELQGYLEKDRSRQQHFLYPLLFQEYIYALAHNHGLNGSIFYEPVEVFGYDNKSSLVLVKRLITRIYQQNFLISLVNDSNQNRFVGYNHNNFFFSHFHSQMISESFAIIVEIPFSLRLVSYFEEKEIPKYHNLRSIHSIFPFLEDKLSHLNYVSDILIPHPIHMEILVQILQCWIQDVPFLHLLRFFLHEYHNLNSLLITQKKSIYVFSKENKRLFRFLYNSYVFEWEFLLVFIRKQFSYLRLTSYGTFLERTHFYEKIEHLQIKDFVVVCRNYFHRTLWFCKDPFMHYVRYQGKAILASKGTHLLMKKWKYHFFNFWQYYFHVWSQPYRIHINQLSNYSFYFLGYLSSLLLHFSAVRNQMLENSFLINTITKKFDTIVPVIFLIGSLAKAKFCTVSGHPISKPIWTDLSDSDILNRFGRICRNLSHYHSGSSKKQGLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLIFPKTTPFFLHGSHRERIWYLDIIRINDLVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DHX32_HUMAN
Sequence: MEEEGLECPNSSSEKRYFPESLDSSDGDEEEVLACEDLELNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEVKNKHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYYFSNLPPSESKDILQQVVDHLSPVSTMNKEQQMCETCPETEQRCTLQ
What are the official names of this protein?
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DEAD/H box 32, DEAD/H helicase-like protein 1, DHLP1, DEAH box protein 32, HuDDX32.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: HTPX_ALKEH
Sequence: MKRIGLFLLTNLAILVVLGVVLFILQAVFGVRTLDEAGVGLDYTGLLIIAAVIGFGGSFISLAMSKFIAKRMTGARVIEKPRSEAEQWLVDTVRRFARQEGIGMPEVAIYDAPDMNAFATGARRNNSLVAVSTGLLQSMTRDEAEAVIGHEIAHISNGDMVTLTLIQGVVNTFVVFFSRIIGHFVDRVVFKTEQGHGPAYFITSIFAQIVLGILASVIVMWFSRQREYRADAGGAKLAGRDKMIAALERLKRSVDQEHLPDQLEAFGINGNRGGGMKEWFMSHPPLDDRIAALKEGRHLRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAN1_YEAST
Sequence: MYNPYQQQGMGYQQQQQQQQQQPNGFYPQQQQGQSSNQPQGQPQPQQQMAFNQPQATGIGGMPQSFGNSFSSMPQQPQTGYNNNGNNGSVYGNGNFGQQPQQQQQQAKPQHTGYVPNSSMPMMNTTGTMPPPNPAQQPQLQSIQPQGTGYYQAANTANVHSVQPLQSQGTGYYVSTPNLISSNQTQQPLQAQGTGYYQSQPQQVPPPQQAQSLQPLKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNGLNNDIKIPAIRLSFITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYELDSKTKNEVSSFIDAINLSIANQDSSANDAPKTPFDEFITAGVQNLQPQPTGYMPQTSFGIPLQSQITGGGVASALNPQSTGFMAPTTFNMSMNTGTPGLNPQITGGAPASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGVNLGPQLTGGALQSQYTGGYGSVMPQQSGPASMPNLSFNQQGLQSQLTGLQPQPTGFLPPSNFSATMPLTAQKTGFGNNEIYTKSNFNNNLIDNSSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSSTKLLDNLKNQLKTEPTTTKEKPSFGKIDALSYKNNDDDVLPNYRNRRKVYSAKNEEQSSFSSPSAKSVNHSSSTLQTDDISVDKTVEKKTAKPKYAGFSREINLKNIASLENEIKNISNPENCYDSSIPSDLTSRFDAIIAKLPNLFNEISTIDNEITNAKIQLYRKKNPSSIIGSGPNGEITENDRKKAKSRALLRARMSALTGKSTESEDSLSMEDEQQSAEIKRIQQENGKNQEIIKDIRSSISDISASLKSTMTGSNMISNQEFERWEFGIGLEDGVREFLDDLKSNSNKSVTESSPFVPSSTPTPVDDRSSSPSYSQFKTAEERAAYLKEQAKKRMKEKLAKFDKNRRNVTQSSRSISSENSREQPQQIAGSSNLVEPRATPFQEEKYVEVAQPTQPVQSTQPVQPTQPVQPTQPVQPTQPVQPTQPVQPTQPVQNVYNAKQESDDEDEDDEEKRLQEELKRLKLKKKADKEKRLAALRKQIEDAQNESDEEETNGKDNFGGHVNVPQAAPVAPSAAFSQNSTNAPRSVHAAVTPAAGKNSTGLPSTTMGHNPYFKDASASSTSTFDARAAEMQRRIQRGLDEDEDDGWSDEDESNNRVAVDNKVEEAKIGHPDHARAPPVTAAPLPSVTPVPPAVPVPQANTSNEKSSPIPIAPIPPSVTQEPPVPLAPPLPAVDGFQEPPIPSAPAIATAVQKSGSSTPALAGGVLPPPPPLPTQQASTSEPIIAHVDNYNGAEKGTGAYGSDSDDDVLSIPESVGTDEEEEGAQPVSTAGIPSIPPAGIPPPPPLP
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.  Required for the bipolar budding of diploid cells and the correct distribution of chitin at the cell surface.
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein PAN1, Mitochondrial distribution of proteins protein 3.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: PANC_THEPX
Sequence: MIVTDKISDVRNIIKEQKLSGKKIGLVPTMGYLHEGHLSLVRIAKKHSDFVAVSIFVNPIQFGPNEDFDRYPRDLERDLKLLEKEGCDLVFAPSVEEMYPSELLTTVNVDKITEKLCGAFRPGHFKGVTTVVAKLFNIFTPDIAVFGQKDAQQVAVIKKMVEDLNFPVEIIKAPIVRESDGLAMSSRNVYLNPEERKAALILSKSLKEAEKLLLNGERNANTIIKKVNEVLNSEPLCKVQYVSCVHPDTLEDLTYIKDKALIAIACFIGTTRLIDNLLWGENI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNPY3_BOVIN
Sequence: MEPLPEPASGPRPRPHRLLLLSLLLLLLPLLPAPELGPRQARAEDTDWVRLPSKCEVCKYVAVELKSAFEETGKTKEVIDTGYGILDRKASGVKYTKSDLRLIEVTETICKRLLDYSLHKERTGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEFEEVIEDWYRNHQEEDLTQFLCANHVLKGKDASCLAEQWSGKKGDTAALGGKKSKKKSGRAKGLGGGSSKQRKELGDLDGDPSPEEDEGIQKASPLTHSPPDEL
What is the function of this protein?
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1.  Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum.  Consequently, required for both innate and adaptive immune responses (By similarity).
What are the official names of this protein?
Protein canopy homolog 3.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: M840_ARATH
Sequence: MKLLVAPESIKTMTSCPAICPLILMDLSQLLNLPSTAKTTRVIPLLHPHLILLSFSLFQLHQPHPTHLLHPQPYTLILCPYICDQDSTCHHNENKAPCSFYPDQTVSGMVPFYVLGIGRAR
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00840, ORF121b.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YABN_BACSU
Sequence: MAGKITVVGLGAGDMDQLTIGIHKLLTKADTLYVRTKDHPLIEELEKETKNIRFFDDIYEKHDQFEAVYEEIADILFEAARREDVVYAVPGHPFVAEKTVQLLTERQEKENVQVKVAGGQSFLDATFNVLQIDPIEGFQFVDAGTLSADELELRHHLIICQVYDQMTASEVKLTLMEKLPDDYEVVIVTAAGSRGEEIRTVPLFELDRNVALNNLTSVYIPPIKEEKLLYHEFSTFRSIIRELRGPNGCPWDKKQTHQSLKQYMIEECYELLEAIDEEDTDHMIEELGDVLLQVLLHAQIGEDEGYFTIDDVIKGISEKMVRRHPHVFKDVKVQDENDVLANWEDIKKAEKNTSESSLLDSVPKTLPALSKAAKLQKKAAKVGFDWEDVSDIWEKVSEEMKEFSSEVSEAPHEHNLKAEFGDILFALVNVARFYKIEPEEALTMTNDKFRRRFSYIEETAKEEGVELADMSLEDMDKLWNEAKETERRS
What are the official names of this protein?
Uncharacterized protein YabN.
Protein: RL7_BACCN
Sequence: MTKEQIIEAVKSMTVLELNDLVKAIEEEFGVTAAAPVAVVGGAGEAAAEKTEFDVELANAGAQKIKVIKVVREITGLGLKEAKELVDNTPKVIKEGASKEEAEEIKAKLEEVGAAVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SYT_THESM
Sequence: MRILLIHSDYLEYEVKDKALKKPEEISENQKKGRLDEVLAVFMSVEKVDEQNPEEIVKKAVKEIEEVVSQVKTNNIFVYPFAHLSSELGSPDVALRILKEIENELKNKGYNVRRAPFGYYKAFKLSCKGHPLAELSRTIVPGEAKKEEEVPEALKKEEELVSYWYILTPEGELVEVDKFDFSGYENLKKFANYEINKSRLVTEEPPHVKIMLEQELVDYEEGSDPGNLRYYPKGRLIKSLLENYVTDKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYVVKSGDKRFFLRFAACFGQFLIKKDATISYRHLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTVAKNLQQAMEEFKKQYKLSMEVLKGVGLTPEDYEVAIRFTEDFWNENKDFIVDLAGIIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENSQRFGITYYDEEGQEKYPLLLHCSPSGAIERVMYAILEKQAKIMKKGKKPMYPLWLSPIQVRIIPVSEKYLDYALYIAGKLEGAKIRADVDDRNERLNKKIREAEKEWIPYIIVVGENEKRMGVITVRKREDNKQYEIQVEDLIKEIRQKTEGFPYKPRPLPPLVSMRPKFRG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRB2_HUMAN
Sequence: MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
What are the official names of this protein?
Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane (PubMed:19584355). Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325). Activated receptors are also detected within the Golgi apparatus (PubMed:27481942).
Protein: VRAB_STAAW
Sequence: MNQAVIVAAKRTAFGKYGGTLKHLEPEQLLKPLFQHFKEKYPEVISKIDDVVLGNVVGNGGNIARKALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQAGAGKVYIAGGVESTSRAPWKIKRPHSVYETALPEFYERASFAPEMSDPSMIQGAENVAKMYDVSRELQDEFAYRSHQLTAENVKNGNISQEILPITVKGEIFNTDESLKSHIPKDNFGRFKPVIKGGTVTAANSCMKNDGAVLLLIMEKDMAYELGFEHGLLFKDGVTVGVDSNFPGIGPVPAISNLLKRNQLTIENIEVIEINEAFSAQVVACQQALNISNTQLNIWGGALASGHPYGASGAQLVTRLFYMFDKETMIASMGIGGGLGNAALFTRF
What are the official names of this protein?
Putative acetyl-CoA C-acetyltransferase VraB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: HGD_BURPS
Sequence: MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQFSGTAFTAPRGHNRRSWLYRIRPAAVHRPFELVSGERRIVAEFGDSDDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFFYSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRDFLTPHASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASSIDTSKPNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: OMPC_ECOLI
Sequence: MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGNPSGEGFTSGVTNNGRDALRQNGDGVGGSITYDYEGFGIGGAISSSKRTDAQNTAAYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF
What is the function of this protein?
(Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA-EC536-mediated toxicity.
What are the official names of this protein?
Outer membrane porin C, Outer membrane protein 1B, Outer membrane protein C, Porin OmpC.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: METN2_STAAB
Sequence: MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKYAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.