PharMolix/UniProtQA huggingface dataset:
Protein: PDH2_PENVA
Sequence: MARCFVVLAFLALAAMSLQVATAQDDLKYFEREVVAELAAQILRVAQGPSAFVAGPHKRNSELINSLLGIPKVMNDAGRR
What is the function of this protein?
The pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas.  May also function as a neurotransmitter and/or neuromodulator (By similarity).
What are the official names of this protein?
Pigment-dispersing hormone type 2.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH4_BURP6
Sequence: MNLMNPEFAMPDVQSTVDTRQMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRFVALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRGA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: MUT7_CAEEL
Sequence: MEEEPYKRKLTKAEKKAKYRTDYAEPLKSRREVLKAIMNGPESERERKVRAKNREFFNEDYRSGVNIYGMAVDMMKAMPDRGKTSGQSLAVWYLEDFGVWLKESGQETELRQKYLTGTIQINALDVCTIGQKQLLSEIFDITKEKFTEDITQLLDAAIKKQDFSVAADMAIQYNLLRDHHFEHLVLPLMLSGKDQTAYKLISNNERMQQQLVEFFDRMVGISVVAVEEMLKPYKETKIMTIPMEKLTGKTLDKLISTIINKNTHEYNFSRELSKFAKNHSQNGNLKALKFNISERYEKGKSDDNYFQHMVETFTKAEDVREPILFYLWSSNDTEKQIDAICFAIYLGIASSSSYQLPNVMRDFFRQPDSKLREAKELLVRRKTLQVPLNGEQLFVFENERRTQIHMVKTESEMNYLCSEIKSLSDEPAPVYVGFDSEWKPSNLTAVHDSKIAIIQLFFKNCVWLVDCVELEKANMADDWWQKFASRLFGDSPVKVVGFDMRNDLDAMATIPALKSSMKIEDTKNAFDLKRLAENVCDIDMEILELPKKTFKLADLTHYLLGLELDKTEQCSNWQCRPLRKKQIVYAALDAVVVVETFKKILSIVEEKNKDADIEKIVRESNVMAPKKDKGHKSYRKLKTIPWLELYDILRSHRNPTRSPQRPHDIKVIVDTMLIGFGKNLRRVGIDVILPKDVSDFRKYLKEIERVGGEHLRHIITVPSKSYEALKMDYDNYTIAIPELNNMSPVDQLIEFFDLFNVDIRPEDVYPRCTECNSRLQIKFPGPVLHFLHQYCVIHVQNVYRADMSEFPLEEWWNRMLHINPDDYDGVKVEMSRPSPTSKWIVATVPTGCLHITRQTALHTNLPDGIEVRIHKVPDDEFKRRNLSFYVCGECGTVACDGRGNQASESTSQEC
What is the function of this protein?
Represses the transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages.  Also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers.
What are the official names of this protein?
Exonuclease mut-7, Exonuclease 3'-5' domain-containing protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the mut-7 family.
Protein: WAPA_OXYMI
Sequence: KDRPKKPGLCPPRPQKPCVKECKNDDSCPGQQKCCNYGCKDECRDPIFVG
What is the function of this protein?
Damages membranes of susceptible bacteria (PubMed:17044815).  Has antibacterial activity against the Gram-positive bacteria B. megaterium and S. warneri (PubMed:17044815, PubMed:20669184).  After a 45-minute treatment with this protein, B. megaterium have no visible pili and are smooth (PubMed:20669184).  Has no antibacterial activity against the Gram-positive bacteria B. thuringiensis, S. aureus, S. clavuligerus and B.  anthracis, or the Gram-negative bacteria E. coli and A. tumefaciens (PubMed:17044815, PubMed:20669184).  Has no hemolytic activity (PubMed:17044815).  Does not inhibit the proteinases elastase and cathepsin G (PubMed:17044815).  Is not toxic to mice (PubMed:17044815).
What are the official names of this protein?
Omwaprin-a, Omwaprin, Oxywaprin-a.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUOX_CHICK
Sequence: APSYPRYTREEVGRHRSPEERVWVTHGTDVFDVTDFVELHPGGPDKILLAAGGALEPFWALYAVHGEPHVLELLQQYKVGELSPDEAPAAPDAQDPFAGDPPRHPGLRVNSQKPFNAEPPAELLAERFLTPNELFFTRNHLPVPAVEPSSYRLRVDGPGGRTLSLSLAELRSRFPKHEVTATLQCAGNRRSEMSRVRPVKGLPWDIGAISTARWGGASLRDVLLHAGFPEELQGGEHVCFEGLDADPGGAPYGASIPYGRALSPAADVLLAYEMNGTELPRDHRFPVRVVVPGVVGARSVKWLRRVAVSPDESPSRWQQNDYKGFSPCVDWDTVDYRTAPAIQELPVQSAVTQPRPGAAVPPGELTVKGYAWSGGGREVVRVDVSLDGGRTWKVARLMGDKAPPGRAWAWALWELTVPVEAGTELEIVCKAVDSSYNVQPDSVAPIWNLRGVLSTAWHR
What is the function of this protein?
Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
What are the official names of this protein?
Sulfite oxidase.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: PYG2_NOSS1
Sequence: MSIPLLEYKPSSQNQRVPGYEVPNEDTPRIYRIEDAAYDSELKELIWATYRQVFSEHVILKFFRQGNLESQLKNRAISVRDFVRGLAKSEAFKTLVIKSNSNYRLVELALKRLLGRAPYNKDEEIAWSIKIATNGWDGFVDALLDSEEYQSNFGENIVPYQRRRYKDRPFNLVTPRYGNYWRDKLESERYIEGDIKNFLELAKSIEIKTVTFTPVSTANIKIPDTTRNTTPTGIPISVNPSANFPVR
What is the function of this protein?
Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome rod-core linker polypeptide CpcG2, L-RC 28.5.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of a phycobilisome rod.
Protein: Y1281_MYCTU
Sequence: MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMSALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQILDVLKAARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPYTVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECLTAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVVRVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGKSTTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVVFQDPVASLDPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHGDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINLLLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPKHEYTRRLLGAVPQPDPARRG
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Rv1281c.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: NU6M_CANLF
Sequence: MMTYIVFILSIVFVMSFVGFATKPSPIYGGLVLIISGGIGCAIVLNFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKAVLAAFITGLLSELLTACYILKDDEVEVVLKFNGMGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVVVTGWSLLIGVLVIMEVTRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYY_GEOMG
Sequence: MSVAEQMAIIKRGATEILLEKELEEKIEKSLSTGVPLRIKAGFDPTAPDLHLGHTVLLHKMRQFQQLGHEVCFLIGDFTGMIGDPTGKSETRKALTREDVLKNAETYKEQVFKILDPKKTRVVFNSEWLGKMTASDMIGLAAQSTVARMLERDDFGKRFANQLPISIHEFLYPLIQGYDSVALKADVELGGTDQKFNLLVGRELQRVWKQSPQSVITMPLLEGLDGVNKMSKSLGNYIGINEPADEIFGKIMSISDELMLRYYELLSDLTLAEIEKLKAAMRDGDVHPMAAKKQLAREIVARYHGAVAADNAEESFVRRFRDNQTPEEMPECILSAEEGKVLLGRLLAEAGLVKSNSEGRRAINQGGVKVNGEKVTNDMLELPGVGEYVLQFGKRRFARIVFK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMTL_NEMVE
Sequence: MGLPPIECPFDIPKPFRHPDLFDKFSNCDPLPIFFLNRWNESFKVFYQNLDDEHRGLFDVVFDVDAKRGDAGAVSKAASAFKGHFTTEEAEMKKGVDAGKLDGAHYKGHCTAHNKFLELFGSFGNNLGDDEINYSMKWLVNHIKSTDFHYKGKLIQ
What is the function of this protein?
Oxygen-binding protein.  The oxygen-binding site contains two iron atoms (By similarity).
What are the official names of this protein?
Hemerythrin-like protein.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: Y2667_HALH5
Sequence: MPKVGVEQSLTAISEELRGMGYDVVQLKQEQDAQGCDCCVITGQDQNVMGIQNAVTQGAVINASGLTAEEVCQQVDQRLRQQ
What are the official names of this protein?
UPF0180 protein BH2667.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: PDAD_THESM
Sequence: MSWTTPKKAILLAASAEGSTKLNAFDNALLKMGIGNVNLVKLSSVIPAYIEWIDELPKNIPVGMLLPTVYAHIESDEPGSTITAALGVGISEGNEGGLIYEYSGYCTKEEAEKMVHKMVEEGFKVRGWKLKEFKAAVAEITVKDRPVAAIAAVVMLPY
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: NUSB_SALSV
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLSGVATNSAYLDGLMKPYLSRLLEELGQVEKAVLRIALFELSKRSDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NSP6_ROTBU
Sequence: MNHLQQRQLFLENLLVGVNNMFHQMQKRPVNTCCRSLQKILDHLILLQTIHSPAFRLDQMQLRQMQTLACLWIHQYNHDHQVTLGAIKWISPLIKELK
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: TMCAL_LEVBA
Sequence: MTLQAAGIVTEYNPFHNGHAYQIAQARQKTGADVIVAAMSGNWVQRGEPAIMDKWQRTEAALAGGVDLVVELSGAAALQPAHLFAQGAIAVLATLKCQWLVFGTEHPDMDYDCLMAHLPSDPAIFKRFDQTYASLFQGYLREQTGITLSAANDILGFFYAVANQQQGQPLQLVPLARRGSQHNDTAVMQGTNYASATAIRAASLAGDWATVQPVVPAKTLALLQQESLISWADFWPLLRYQLISAPVTDMRQRYQITEGVEYRLKRAALEATTFADFMRIVKTKRYTYTRLQRQAAYLLLQALPEEMRPQPQYLRVLGYSKQGQAYLHQIKKHVALPLVSRANRDWQKGVGSLDDRLGALRTLVTGIPQDYGRIPIKKPDSE
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_CHLTB
Sequence: MKSTVEQAMLFEEKSIFENQAIEQGYSQVAGVDEAGRGPLAGPVVAGACILPRGKVFLGIDDSKKLTPKQRRYLYELLLEDPEVDCGVGVISVERIDEINILEATKEAMVQAIASLRSTPDFLLVDGLFLPHKIPSLKIIKGDARSVSIAAASIIAKEYRDELMRKLHVEYPEYGFDKHKGYGTAAHLQALKHFGPCVYHRKSFSPVKESIQEGVCQ
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_DICTD
Sequence: MKVRSSVKKICEKCKIVRRGGRVFVICENPRHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HXC11_MOUSE
Sequence: MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEFSTVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSSHSATKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C11, Homeobox protein Hox-3.7.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGA2_YEAST
Sequence: MSEVAETWVDTWMAKLVNYDYKHFIRLVIIVGGYLLLRNIASRELAKKQLAAQVEKDKRDKEEKRSKDLIDKPDDAATAETTSFGWGKKTRRRVKRQQELFENALEEAKRRNQGLDPDSDADIEELLEE
What is the function of this protein?
Involved in the processing and trafficking of GAS1 and PHO8 glycosylated proteins.
What are the official names of this protein?
Processing of GAS1 and ALP protein 2.
What is the protein family that this protein belongs to?
Belongs to the PGA2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: JAL32_ARATH
Sequence: MAQKVEAQGGIGGDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVDADDYIVAVQVTYDKIFGYDSDIITSITFSTFKGKTSPPYGLDTENKFVLKEKNGGKLVGFHGRAGEILYALGAYFTTTTTPLTPAKKLPAVGGDEGTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDYPSEYITAVEGTYDKIFGFETEVINMLRFKTNKKTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHILPVTN
What is the function of this protein?
Involved in gametophytic development.
What are the official names of this protein?
Jacalin-related lectin 32, Myrosinase-binding protein-like At3g16440, Myrosinase-binding protein-like protein-300B, Protein MATERNAL EFFECT EMBRYO ARREST 36.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: HIS4_STAAE
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_SHEPW
Sequence: MSTGTVVQVIGAVVDVEFPHDAVPQVYDALEIKSEGLVLEVQQQLGGGVVRTIAMGSSDGLRRGLEVVNSGSPITVPVGEKTLGRIMNVLGQPVDEAGPIGEEDRYVIHREAPSYEDQSNTTELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYYEMEDSGVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGKDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRNIASLGIYPAVDPLDSTSRQLDPQVVGQEHYDVANGVQTVLQRYKELKDIIAILGMDELSDEDKTTVFRARKIEKYLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGILDGEFDHLPEQAFYMVGSIDEAVEKANKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: B4GN1_HUMAN
Sequence: MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQKQVRAIDLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIRRFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLLSVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLSRVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMAKHRLLFFKHRLQCMTSQ
What is the function of this protein?
Involved in the biosynthesis of gangliosides GM2, GD2, GT2 and GA2 from GM3, GD3, GT3 and GA3, respectively.
What are the official names of this protein?
Beta-1,4 N-acetylgalactosaminyltransferase 1, (N-acetylneuraminyl)-galactosylglucosylceramide, GM2/GD2 synthase, GalNAc-T.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: SYV_RALSO
Sequence: MTDPNQSLAKSFEPAAIEQKWSAAWEAMGISRATLEAGRPDFCIQLPPPNVTGTLHMGHAFNQTIMDGLARHARMQGANTLWVPGTDHAGIATQIVVERQLDAQGISRHDLGRPAFVDKVWEWKEQSGSTITRQIRRMGASIDWEREYFTMDPKMSRAVSDVFVRLYEQGLIYRGKRLVNWDPVLGTAVSDLEVVSEEEDGALWHIRYPLAQPDAKTGLTHLTVATTRPETMLGDVAVMVHPEDERYAHLIGQAVRLPLSGEADALDTAQWREIPIIGDEYVDRAFGTGVVKVTPGHDFNDYAVGQRHGLPQISVLTLEAKIADTAPATYRGIDRFEARKRIVVDLETLGLLAEVKKHTLMVPRGDRTGVIIEPMLTDQWFVAMSKPAPEGTRFPGRSIAEVALDAVQGGKIKLVPEQWVNTYNQWLNNIQDWCISRQLWWGHQIPAWYDEAGNVYVARTEEEARAQAAAKGHTGAIKRDDDVLDTWFSAALVPFSSLGWPADTPELKHFLPSTVLVTGYDIIFFWVARMVMMTLHFTGEVPFQTVYVHGLVRDSEGKKMSKSEGNTLDPVDLIDGIALEPLLVKRTTGLRRPKDAPNVEKRTRKEFPDGIPAFGADALRFTFASLATLGRNINFDSSRCEGYRNFCNKLWNATRFVLMNTEGQDCGLQECVGDCGPEGALHFSPADRWIVSLLQRVETEVEKGFADYRFDNIASAIYKFVWDEYCDWYLELAKVQIQTGTPAQQRATRRTLLRVLETVLRLAHPIIPFITEELWQKVAPMAGRAKGDGTESLAQQEYPRAVLAKIDEQAEQWVQQLKALVDACRNLRGEMSLSPAQRVPLYAHGDAEFLQAAAPYVQALGKLSEVKVYTDAAAMEQDGAGAPVAIVGENKLLLKIEIDVAAEHARLSKEIDRLRGEIVKCEGKLGNESFVARAPAAVVEQEQKRLADFKATLGKLEAQIARLPVQTA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGD2_PONAB
Sequence: MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETLKASKALEVSEDVKVSKASGVSKATEVSKTPEAQEAPATQASSTTQLTDTQVLATENKSVAADTKKQNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQASADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASGTTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDPKEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNSASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFSYK
What is the function of this protein?
Regulates the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule.
What are the official names of this protein?
Melanoma-associated antigen D2, MAGE-D2 antigen.
Protein: YAEP_SALA4
Sequence: MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALSESVREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein YaeP.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: AQ12B_HUMAN
Sequence: MAGLNVSLSFFFATFTLCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAACTLTRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQGRLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin-12B, AQP-12B.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: XPO1_RAT
Sequence: MPAIMTMLADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFETLFTLTMMQLKQMLPLNTNIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHGQLLEKRLNLREALMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDIPPRRQLYLTVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTEIIMTKKLQNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIFDAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTPLNPGSPVSNQMFIQDYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEERETALRQAQEEKHKLQMSVPGILNPHEIPEEMCD
What is the function of this protein?
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs.  In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase Ran in its active GTP-bound form.  Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  Involved in U3 snoRNA transport from Cajal bodies to nucleoli.  Binds to late precursor U3 snoRNA bearing a TMG cap (By similarity).
What are the official names of this protein?
Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Note=Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm (By similarity).