PharMolix/UniProtQA huggingface dataset:
Protein: URED_CITK8
Sequence: MHSPHADKGNALDTVAHKTLTRGWQAELDLRFTRAAHKTVLTSARHVGPLTVQRPFYPEDDVCHLYLLHPPGGIVGGDELTISATLATDSHALITQPGSGKFYRSRGPQAQLRQDFYLAPQATLEWLPQDTILFPGANANIQSVFHLAQESRLLAWDLLCLGRPVMQETFSHGTLRNRLEVWRDGTPLLIERLHLEGGSLHTVARHPWSGTLLCYPATEKMLDGVREQIAPLGDYAGATLIDSLLALRFLGHDNLLIQRVMRAVWQSLRPQLTQKPPLLPRIWQT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_BURP0
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADIDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC16_MACFA
Sequence: MTDSDEDALKVDQGPSQDIPKPWVIPAPKGFLQHIFGTSQVFQSICDVKPKVTGLTVPLKVREYYSRGQQCLEQADWETAVLFFSRALHLDPQLVDFYALRAEAYLQLCDFSSAAQNLRRAYSLQQDNCKHLERLTFVLYLQGQCLFEQCAFLDALNVFSHAAELQPEKACFRYRCMACLLALEQHPACLSLITEELKQDTTNADVYILRARLYNFLQKPHLCYRDLHGALLLNPKHPQARMLLQKMVAQAQQARQDAGILAVQGRLQHALQRINCAIENNPLDPSFFLFRGTMYRRLQEFDGAVEDFLKVLDMVTEDQEDIMRQAQRQLLLTYNDFAVHCYRQGAYQEGVLLLNKALRDEQQEKGLYINRGDCFFQLGNLAFAEADYQQALALSPQDEGANTRMGLLQEKMGFCEQKHRQFQKAEDHFSTAIRHNPQKAQYYLYRAKSRQLLQNIFGARQDVATVLLLNPKQPKLSLLMTNLFPGMSVEEVLSTQIAHLARLQLERMVEGSLQAGGPQGIVGMLKQWELERQKALALQHSWKQGEPLIETSEKLQATPEIPQVEPGSSEGQAEAPKEEEEKEEEEQKEEEEQKKEEKKEEKKPKLTPSKVASLSESYLDQTSLASSMSFRTTCTSETETSAICQEYRSTSATAMTFSDSSLLKTQSSDSGNNREALSHGPRKIKDIQGQRQSLSKTQATQSQRQNFSKTKAAAHRRNSSKTKATQGQGRRSSKTEATQGQRQSSSEIETSQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSKLDATQGRRRGLLRSSTKTEAFYDSNWSLSKTEDVQGQGQRTSKAEAAQGKSRGMSSTSSKAESTWGPSPSVSKTEVGQDLTYYEVL
What are the official names of this protein?
Tetratricopeptide repeat protein 16, TPR repeat protein 16.
Protein: TPM2_RABIT
Sequence: MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.  The non-muscle isoform may have a role in agonist-mediated receptor internalization.
What are the official names of this protein?
Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: AIM24_ASPFN
Sequence: MSQPLRRGVRAVSWTRVLPPRARQGQTRCLQIRAAAAEQPSSANGNNLPVVGTPSSAESADARFDVIGAPYSLLSVSLSASQNLFTRRGTLVGLSGKADNVVSTLSVLEPFRRAVVGVPFLYQKVSSASPVTALVSVRSPTTSFAVVHLDGSVDWMVAQRRALLAWTGRSLSIKPTINTSLSVSHWGSSEVTGRGLLALVGAGQLYQVEVKAGEQYIVHPSNVVAYTMTNNPPRPYRFKSTTLKFQVPGLKGWPSFIQDSKFIRDMSGSDTWKTAMNIFHKIRTWSRMTIWGDRLFLQFDGPATILIQTRGPRINEVLTSHEVNEIASAPRGLTIGPAKPAEEKKPSADEEYRKAAEEAVNAAPAPTRTVEQLEQEIRGSAQSIATLTKEGKVIFEKPGQQN
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YL591_MIMIV
Sequence: MNITNINTTRIPAGTRLYLTKKKYNKFYIQPDKTLVNDNLFVAYDVKIGGVIAIPQGTRVLGNWVAESSPSIAVQLQLTKIFLYGSGQNISADSDLVETLVDYNSDEIDCAPYLYKIHHFKSPAGIYRRIVNTKCRSKILTDNNRNSIYLEVNTKEISVVLNEDIIPMPDLSKMPVPQSPSVPTMPSVNNDQPTQKPNKITRNYKPKHQHNYKPNYQPNYQPNYGQNCSNSHSNDYFSDYPTEHSGDSSSYSTYEDDDF
What are the official names of this protein?
Uncharacterized protein L591.
What are the subcellular locations of this protein?
Virion.
Protein: AQP11_MOUSE
Sequence: MSALLGLRPEVQDTCISLGLMLLFVLFVGLARVIARQQLHRPVVHAFVLEFLATFQLCCCTHELQVLSEQDSAHPTWTLTLIYFFSLVHGLTLVGTASNPCGVMMQMILGGMSPEMGAVRLLAQLVSALCSRYCISALWSLSLTKYHYDERILACRNPIHTDMSKAIIIEAICSFIFHSALLHFQEVRTKLRIHLLAALITFLAYAGGSLTGALFNPALALSLHFPCFDELFYKFFVVYWLAPSVGVLMMILMFSFFLPWLHNNQMTNKKE
What is the function of this protein?
Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organes like liver, kidney and brain (PubMed:21118806, PubMed:21251984).  In situation of stress, participates in endoplasmic reticulum (ER) homeostasis by regulating redox homeostasis through the transport of hydrogen peroxide across the endoplasmic reticulum membrane thereby regulating the oxidative stress through the NADPH oxidase 2 pathway (PubMed:23275615, PubMed:30656220).  Plays a role by maintaining an environment suitable for translation or protein foldings in the ER lumen namely by participating in the PKD1 glycosylation processing resulting in regulation of PKD1 membrane trafficking thereby preventing the accumulation of unfolding protein in ER (PubMed:24854278, PubMed:18606867).  Plays a role in the proximal tubule function by regulating its endosomal acidification (PubMed:16107722).  May play a role in postnatal kidney development (PubMed:18701606, PubMed:23486012, PubMed:27582095).
What are the official names of this protein?
Aquaporin-11, AQP-11.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes mainly to the periphery of lipid droplets. it accumulates partly in mitochondrial-associated endoplasmic reticulum membranes.
Protein: RK20_SOLLC
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTITQQKIRALVSAHRDRDRKKRDFRRLWITRINAVIRERGVSYSYSRLIHDLYKRQLLLNRKILAQIAISNRNCLYMISNEIIKEVDWKESTRII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MPK6_ORYSJ
Sequence: MDSSSGGAGGGGGAQIKGMGTHGGRYVLYNVYGNFFEVSSKYAPPIRPIGRGAYGIVCAAVNSENGEEVAIKKIGNAFDNHIDAKRTLREIKLLRHMDHENIIAIKDIIRPPRRDNFNDVYIVSELMDTDLHQIIRSNQPLTDDHCQYFLYQLLRGLKYVHSANVLHRDLKPSNLFLNANCDLKIADFGLARTTTETDLMTEYVVTRWYRAPELLLNCSQYTAAIDVWSVGCILGEIVTRQPLFPGRDYIQQLKLITELIGSPDDSSLGFLRSDNARRYMKQLPQYPRQDFRLRFRNMSAGAVDLLEKMLVFDPSRRITVDEALHHPYLASLHDINEEPTCPAPFSFDFEQPSFTEEHIKELIWRESLAFNPDPPY
What are the official names of this protein?
Mitogen-activated protein kinase 6, MAP kinase 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: POLG_LIVN1
Sequence: SRCTHLENRDFVTGTQGTTRVTLVLELGGCVTITAEGKPSVDVWLDAIYQESPAKTREYCLHAKLSETKVAARCPTMGPAVLTEEHQIGTVCKRDQSDRGWGNHCGLFGKGSIVACVKAACEAKKKATGYVYDANKIVYTVKVEPHTGDYVAANETHKGRKTTTFTVSSEKTILTLGEYGDVSLLCRVASGVNLAQTIILELDKTAEHLPTAWQVHRDWFNDLALPWKHDGNPHWNNAERLVEFGVPHAVKMDVYNLGDQTGVLLKALAGVPVAHIEGNKYHLKSGHVTCEVGLENLKMKGLTYTMCDKSKFTWKRTPTDSGHDTVVMEVTFSGSKPCRIPVRAVAHGSPDVNVAMLITPNPTIENDGGGFIEMQLPPGDNIIYVGELSHQWFQTGSSIGRVFQTTRKGIERLTVIGEHAWDFGSAGGFFSSIGKAVHTVLGGAFNSIFGGVGFLPKLLMGVALAWLGLNTRNPTMSMSFLLAGGLVLAMTLGVGA
What is the function of this protein?
Binds to host cell surface receptor and mediates fusion between viral and cellular membranes.  Envelope protein is synthesized in the endoplasmic reticulum in the form of heterodimer with protein prM.  They play a role in virion budding in the ER, and the newly formed immature particle is covered with 60 spikes composed of heterodimer between precursor prM and envelope protein E.  The virion is transported to the Golgi apparatus where the low pH causes dissociation of PrM-E heterodimers and formation of E homodimers.  prM-E cleavage is ineficient, and many virions are only partially matured.  These uncleaved prM would play a role in immune evasion.
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CUGC_CONPB
Sequence: SCSCQKHFSCCD
What are the official names of this protein?
Conotoxin pc16c.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVC_VIBA3
Sequence: MSIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALKLGQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKSMVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVALAGKATGARKGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ISPT_ENTFA
Sequence: MLRFFPQKNKYVEEASQYAFDKEGQIPQHIAIIMDGNGRWAQNRRLPRIAGHKEGMDTVKKITKHASHLGVKVLTLYAFSTENWKRPTDEVNFLMQLPVDFFDTFVPELIKENVKVNVMGYQEFLPSHTQDAVKRAIEQTKDNTGMVLNFALNYGARAELLTAMKQIAAEVSEKAYTADEITEETIADHLMTGFLPTELRDPELLIRTSGEERISNFLLWQIAYSELFFTKALWPDFSGDTLETAIASFQNRNRRFGGLKETTETEGSDPQ
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: BIOB_RHOPS
Sequence: MNSIDLPSLAQALADSTPTIRHNWTREEAAAIYHAPFADLIFRAQTIHRQSFDANAVQCNQLLNVKTGGCAEDCGYCSQSSHHDTALPASKLMDPAKVIEGAKAARDAGATRYCMGAAWRSPKDRDMAPVIEMVKGVKALGMEACMTLGMLTDDQAKQLADAGLDYYNHNIDTSEEFYSSVVKTRSFGDRLETLEKVQDAGIKVCCGGILGLGEKPTDRVEMLRTLANLPQHPESVPINMLIPIEGTPIAATATPVDPFEFVRTIALARIMMPKSDVRLAAGRTAMSDEMQALCFLAGANSIFIGDTLLTTPNPGDSKDRALFARLGITPRDDLGVHAHGNA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: VDTF1_BYSSP
Sequence: MDGKALTASSLFDITGRVAVITGGGTGLGLMMAKALEANGAKVYILGRRLEPLQEAAKQSTHGNIHPVQCSVTSHADLQGVVDHIAAKDGYINLLVNNAGISTPNLGPHATRPTPKWDISKVRDYWFHKSFADYAAVFETNTTASLMVTFAFLELLDKGNKKSEEEAKASQARNGAGKARIEYVRSQVVTLSSVGGFGRDNSAFIYGASKAAATHMMKNLATYLAPWKIRVNVIAPGYFNTDMMGNFYKATGGRLPASLAPEERFGDAQEIGGTIVYLASKAGAYCNGMVLLVDGGYVSNKPSSY
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity (PubMed:31304040, PubMed:31045362).  The first step is performed by the polyketide synthase VdtA which condenses one acetyl-CoA and 6 malonyl-CoA units to form the heptaketide monomer backbone of viriditoxin (PubMed:31304040).  The product of VdtA is then O-methylated on C7 by the O-methyltransferase VdtC (PubMed:31304040, PubMed:31045362).  The O-methyl group is important for the stereoselective coupling of the monomers at the final step of viriditoxin biosynthesis (PubMed:31304040, PubMed:31045362).  The short-chain dehydrogenase/reductase VdtF then acts as a stereospecific reductase converting the pyrone to dihydropyrone via the reduction of the C3-C4 double bond (PubMed:31304040, PubMed:31045362).  The FAD-binding monooxygenase VdtE then converts the ketone group into a methyl-ester group to yield semi-viriditoxin (PubMed:31304040, PubMed:31045362).  Finally, the laccase VdtB is involved in dimerization of 2 semi-viriditoxin molecules to yield the final viriditoxin (PubMed:31304040, PubMed:31045362).  VdtB is responsible for the regioselective 6,6'-coupling of semi-viriditoxin, which yields (M)-viriditoxin and (P)-viriditoxin at a ratio of 1:2 (PubMed:31304040, PubMed:31045362).  The non-catalytic carboxylesterase-like protein VdtD affects the stereochemistical outcome of the coupling (PubMed:31304040, PubMed:31045362).  The highly reducing polyketide synthase VdtX is not involved in viriditoxin synthesis, but might possibly play a role in the production of additional metabolites not identified yet (PubMed:31304040, PubMed:31045362).
What are the official names of this protein?
Short-chain dehydrogenase/reductase VdtF, Viriditoxin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: C3H24_ORYSJ
Sequence: MFLLMASVLPIRQAPMNGTPISASAAAGVDGVGAAVALAAATKKSAAAAAAVAEMAKTLTVDTDDAFAGLLELAADDDAEGLRRALERAPPAAADEAGLWYGRRKVLEHRTPLMVAATYGSLAVLRLLLSLPSVDVNRRCGSDGTTALHCAASGGSPSCVEAVKLLLAAGADADATDASGYRPADVISVPPKMFDAKIALQDLLGCPKAGHGVLRVVTRAANSMLSPVSSPTAEDARSPSAAVMMTTKFADLPRVVTSEKKEYPVDPSLPDIKNSIYASDEFRMYSFKIRPCSRAYSHDWTECPFVHPGENARRRDPRKYHYSCVPCPDFRKGVCRRGDMCEYAHGVFECWLHPAQYRTRLCKDGTSCNRRVCFFAHTTDELRPLYVSTGSAVPSPRASATATMEMAAAMGLMPGSPSSVSAVMSPFTPPMSPSGNGMPPSLGWQQPNVPTLHLPGSSLQSSRLRTSLSARDMPADDYSLMQDIDSQLINDLCYSRIGSSTGNHTSRTKSLNPSNLDDLFSAEMVSSPRYSNADQGGMFSPSHKAAFLNQFQQQQQALLSPINTVFSPKSVDNQQLPSHSSLLQASLGISSPGRMSPRCVESGSPMNSHLAAALAQREKQQQTMRSLSSRDLGPSAARASGVVGSPLSSSWSKWGSPSGTPDWGVNGEELGKLRRSSSFELRSGGDDPDLSWVHTLVKESPPEKQVTTAESINSVGPSPLMPPSVSNGEGPSLNAPLDGHDQAAVIGALLEQMQLDQHIGSLAT
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 24, OsC3H24.
Protein: MURA_BEII9
Sequence: MDRIRIVGGRTLEGTIKISGAKNAALPLMIASLLTSETLTLENVPALADVNMLLRILGHHGVDYSVNGRRAGEEPHASRAIHLTAGTIVDIMAPYDLVSKMRASFWVIAPLLARMGEARVSLPGGCAIGTRPVDLLLMVLEKLGAKIEIEAGYVHAKAPKGLHGAEITFPKVTVGGTHTALMAASLAQGHTLLVNAAREPEIVDLANCLTKMGAKIKGAGQSTVEIEGVGRLSGASHKVLPDRIEAGTYAIAVAMAGGDVLLEGAEADLLQTALDTIEQAGARISVTNEGIRVRRNGAGLQPVDVTTAPFPGFPTDLQAQFMALMTKAKGSSTITETIFENRFMHVQELARLGAHIRLEGDAAIVEGVETLQGAPVMATDLRASVSLVIAALAAQGETMVNRVYHLDRGFEHLEEKLGRCGAIIERISGTA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_ECOSM
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYTIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHLINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BRAC_PSEAE
Sequence: MKKGTQRLSRLFAAMAIAGFASYSMAADTIKIALAGPVTGPVAQYGDMQRAGALMAIEQINKAGGVNGAQLEGVIYDDACDPKQAVAVANKVVNDGVKFVVGHVCSSSTQPATDIYEDEGVLMITPSATAPEITSRGYKLIFRTIGLDNMQGPVAGKFIAERYKDKTIAVLHDKQQYGEGIATEVKKTVEDAGIKVAVFEGLNAGDKDFNALISKLKKAGVQFVYFGGYHPEMGLLLRQAKQAGLDARFMGPEGVGNSEITAIAGDASEGMLATLPRAFEQDPKNKALIDAFKAKNQDPSGIFVLPAYSAVTVIAKGIEKAGEADPEKVAEALRANTFETPTGNLGFDEKGDLKNFDFTVYEWHKDATRTEVK
What is the function of this protein?
Component of the high-affinity leucine, isoleucine, valine transport system I (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids (PubMed:2509433).  Binds L-leucine, L-isoleucine, L-valine, L-threonine and L-alanine with nanomolar affinities.  Can also bind L-homoserine with high affinity (PubMed:31627455).
What are the official names of this protein?
Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, LIVAT-BP, Leu/Ile/Val/Thr/Ala-binding protein.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RPOB_SHEWM
Sequence: MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLAASIILRALDYSTQDILDLFFDRVNFKIKKDSLVMDLVAERLRGETASYDIKDVEGTIIVEKGRRITARHIRQLEKSNTTELEVPVDYIVGKISGQDYIDPDTGEVLVSANAEMTLEDLAKLSLAGIKEISTLYINELDNGAYMSDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLGIDDDEGTGILSKEDIVAVMKNIITIRNGNDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVIDGVVTDQVDYLSAIEEGRYVIAQAIVDLDENGRMMDELIACRHKGDSTFMGAADIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERTLAVDSGVVVVAKRGGYIDYVDASRIVVKVNESELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCAMGDPVVTGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHVRQAKKDLTEEFQILEEGVYGRARNLLLSAGFNEAQLDAIPRSQLLSQSIDDEGKQTELEQLAEQHDELKADFDKKFEVKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPVEDMPYDENGNPIDIVLNPLGVPSRMNIGQVLEVHLGAAAKGIGDKIAAMLEEQRELAELRGYIKEVYELGEEVQQRVDIDSFTDDEVVRLAKNLKGGIPTATPAFDGAKEKEIKEMLALAGLPTTGQRKLFDGRTGDEFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTNMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RRP36_PARBD
Sequence: MPILSKLNKRVRARVEEDDFEHFSQESASDGSELGEEDEETDDSDGSTSESDDGSGRDGDESENEDLESDSASDANSDITSSLNNISFGALAKAQASLGKRKRSTTLTADIASKRPKGPSRSPPAPSSKEDQKYPNATKPPQKLSHRTSKHAPTIQSSRHAVTRKRTVIETPAIPQARDPRFDSVVLNHSTNGNPSIATNATIHASKNYAFLNSYRTEELSQLRKRLQNLQREKSKDTHDEREIERLKRQITSMSDRMQTFERKEMEREVLAGHRRKEREAIREGKKSQPWFLKKGDVKREVVTRRFTEMSGKEKQRALERRRKKIASKEKKEMPWARRGVE
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYR_PARXL
Sequence: MLPAHKHTLETLLADTVKQVALASQGASEAAFVSPTITLERPKVAAHGDVACNVAMQLAKPLRANPRQLAQQIVDALLAQPGARDLVEAAEVAGPGFINLRLTAAAKQAVIAAVFAEKERFGRSQRDAGKHVLIEFVSANPTGPLHVGHGRQAALGDALSNVLASQGWDVHREFYYNDAGVQIQTLALSTQARARGLAPGDEGWPASAYNGEYIADIAKDYLNGATVAASDGEPVTGARDVEDLEAIRRFAVAYLRREQDMDLQAFGVKFDQYYLESSLYKEGRVEKTVAALIAAGKTYEQEGALWLRTTDDGDDKDRVMRKTDGTYTYFVPDVAYHVAKWERGFTKVINIQGSDHHGTIARVRAGLQGLGIGIPKGYPDYILHKMVTVMRNGEEVKISKRAGSYVTVRDLIEWSGGATPGSEVDVDLIDEETIRRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVHYVQYAHARICSVIAECKARYNMDESTLADVDVTPLTSERAMALLNKLAEFPDMLQHAADELAPHAVAFYLRDLAGEFHSFYNDKAERVLVDDAAERNARVALLAATRQVLANGLATIGVSAPVKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_BORPE
Sequence: MGNWLLPEGLADVLPAEARRIEELRRELLDLYRTYGFELVAPPLVEYIDSLLSSTGSDLNLRTCKLVDQLSGRTLGVRADMTSQVTRIDAHLLNRAGVTRLCYCGSVLHARPADLLSSRELLQIGAEIYGHAGFEADLEIIQLVMDTLATAGVRNARLDLCHSGVMRAIFDADPQASRHAGDLCTLLREKDVPGLAELASRVDGLGEDTVRALQALATLYGGPEIIARARRELPAVPGMAQALDALQALVDAMPGVTLSVDLADVGGYGYHSGVTFAVYGEDWHDALVRGGRYDDVSCAFGRARPATGFSLDLRKLAAGLTPAEPARAVRAPWGQDPALTDAVRRLRRSGEIVVQVLPGHEQGLDEFVCDRELALQDGAWTVRTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.