PharMolix/UniProtQA huggingface dataset:
Protein: COX1_ARTSF
Sequence: MQRWFYSTNHKDIGTLYFIFGAWAGMVGTSLSMLIRAELGQPGSLIGDEQVYNVIVTAHAFIMIFFMVMPILIGGFGNWLVPIMLGAPDMAFPRLNNLSFWMLPPSLTLLLASSMVESGAGTGWTVYPPLSSAIAHAGPSVDLAIFSLHLAGVSSILGAVNFITTIINMRPQSMSIDRMPLFVWAVGITAVLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIISQESGKKEAFGTLGMIYAMLAIGILGFVVWAHHMFTVGMDVDTRAYFTAATMIIAIPTGIKIFSWIGTLHGTRLTMTPSMLWALGFVFLFTVGGLTGVVLSNSSIDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLMTGLSMNQFLLKVHFFIMFLGVNLTFFPQHFLGLAGMPRRYADYPDTYASWNVISSLGSVMSMIATLMFIFCIWEAMIAKRINIFSLNLSSSVEWNHPHPPADHSYEEITMISTF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUOH_THEFY
Sequence: MTPTTVVSAAALDAEPGLDAFGNDPWWIILIKALAVFVFLMLCVLMMIMADRKVMGRMQQRHGPNRFGPWGLLQSLADGVKLSLKEDLIPRTVDKVIYIAAPMIAAIPAFFAFSVIPVGPEVTMFGVETRLQLTDLPVAVLLVLATASLGVYGIVLAGWASRSPYPLLGGLRASAQVISYEIAMGLSFIAVFIYAGTLSTSGIVEAQQNIWFAVILFPSFVIYLITMIGETNRLPFDLPEGEGELVGGFMTEYSSMKFTMFFLAEYVNMVTVSAMSVTLFLGGYLAPPPITTFWPGANEGWWPALWWLIKFVCVMFLFVWVRGSLPRVRYDQLMKLGWKILIPIQLVWITAVAVIRVLNNQEYPGYVTAIVVGVFGLLVFLGLWAWSRAAAKAKAQEAAEHEAELRARRENPMYGGFPVPPMIAPHYGTSVLAEEPRYQPASAPKREEVSGA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNME_MYCPN
Sequence: MDTKQTMFALATAPFNSAIHIIRLSGPDVYRIINQITNKEVKPLGMRIQRVWLIDHNQKKVDDVLLFKFVAPNSYTGEDLIEISCHGSMVIVNEIIGLLLKHGAVQAQPGEFTQRGYLNGKMSLNQAASVNNLVLSPNTTLKDVALNALAGQVDARLEPLVEKLGQLVMQMEVNLDYPEYTDEQRELVTMNQAVVQITQILNQIVVGQDQLQRLKDPFKIAIIGNTNVGKSSLLNALLDQDKAIVSAIKGSTRDIVEGDFALNGHFVKILDTAGIRQHQSALEKAGIQKTFGAIKTANLVIYLLDARQPEPDPKIIARLKKLKKDFFLVHNKADLVQQSFQVSISAKQKQIQPLVDLLTQYLHQFYSVEQNQLYLISDWQTILLQKAIAELEHFLIKQQNCLFFDILVVHLRAAHEYILQVLGKNTNYDLINEIFKHFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCOR_DATST
Sequence: MAGQTVIVSGLNPAAILQSTIGGATPAPAAENDHTRKVVPLSRDALQDFMVSIITQKLQDEKQPFYVLDLGEVVSLMDQWNAGLPNIRPFYAVKCNPEPSFLSMLSAMGSNFDCASRAEIEYVLSLGISPDRIVFANPCKPESDIIFAAKVGVNLTTFDSEDEVYKIRKHHPKCELLLRIKPMDDGNARCPMGPKYGALPEEVEPLLRTAQAARLTVSGVSFHIGSGDADSKAYLGAIAAAKGVFETAARFGMSKMTVLDIGGGFTSGHQFTTASAAVRSALEQHFHDEQELTIIAEPGRFFAETAFTLATTIIGKRVRGELREYWINDGLYGSMNCVLYDHATVNATPLACMSNRSNLNCGGSKTFPSTVFGPTCDALDTVLRDYQLPELQVNDWLIFPNMGAYTKAAGSNFNGFNTSAIVTHLAYAYPS
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: ARCA_STRPI
Sequence: MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQTKVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNLYFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIEGGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIRCGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVRGRGGPRCMSMPFEREEV
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_PSEMY
Sequence: MKLSRREFAKANAAAIAAAAAGLPLASTASNLITEADMTRLDWNKAPCRFCGTGCSVMVATRDNRVVATHGDVKAEVNRGLNCVKGYFLSKIMYGVDRLTQPLLRMKNGVYDKQGEFQPVSWDQAFDIMAQKIKQAIAEQGPEAVGMFGSGQWTVWEGYAANKLMKAGFRSNNIDPNARHCMASAVMGFMRTFGMDEPMGCYDDIEAADAFVLWGSNMAEMHPILWSRVTDRRLSHPNTRVAVLSTFEHRSFDLADIPLVFKPQTDLLILNYIANHIIESGAVNKDFVGKHTKFARGADDIGYGLRADNPLEMQAKNAAKANTWEDMSFEQFAAFVKPYTLERTAKESGVAAERLKALAKLYADPKRKVMSFWTMGFNQHTRGVWANNLIYNLHLLTGKISEPGNSPFSLTGQPSACGTAREVGTFSHRLPADMLVANPKHRETAEKIWKLPPGTIQEKPGFHAVEQSRKLKDGVLKVYWTQVSNNMQAGPNVMQEILPGWRNPQAFVIVSDVYPTVSAQAADLILPSAMWVEKEGAYGNAERRTQFWHQLVKAPGEAKSDLWQLVEFSKRFTTDEVWPAELLAKAPDYKGKTLYQVLFANGQVDQFPSEQIEAGYANDEAEAFGFYLQKGLFEEYARFGRGHAHDLAPFDSYHAERGLRWPVVDGKETRWRYREGHDPYVEKGSGVQFYGYPDKRALIFALPYEPPAEAPDDEFPFWLSTGRVLEHWHTGSMTQRVEELHGAVPDALVYMHPDDAKALKARRGSEVKVISRRGEIRARIETRGRNKPPRGLVFVPFFDANKLINKVTLDATDPISKQTDYKKCAVKIELVSLA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PTSN_PSEPU
Sequence: MIRLETILTPGRSLVNVPGGSKKRALEKVATVIADQVPELEMQDVFEKLVAREKLGSTGFGNGIAIPHCRLEGSSAPVSALLHLEAPID
What is the function of this protein?
Seems to have a role in regulating nitrogen assimilation.
What are the official names of this protein?
Nitrogen regulatory protein, Enzyme IIA-NTR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDVA_RHOPS
Sequence: MSLFRLYTRVLELLGKERRLGWTLAVANLLLATAQFAEPVLFGRIIDVMSGNLATGALVPETRSPWPLLAAWVGFGLFTILCSATVALHADRLAHRQRQAVLTSYFEHILQLPLTFHTGTHSGRLMKVMLQGTDALWRVWLGFFREHFAAILSLVVLLPLSLYINWRLAILLFALCGVFTVLTTLVVRKTYGMQNEVEAQYSDLSARASDALGNVALVQSYVRVDAEVQGLRFVADKLLAAQMPVLSWWALVTVITRASTTITVLAIFSLGIALNQQGLTSVGEIVMFVSFATLLIQRLEQVVSFVNSLMMEAPRLQEFITVLDAVPAVRDRPDAIDPGRLSGLVEFLDVSFSYDGKRPAIEDLSFTALPGQTIALVGATGAGKSTAIALLHRAFDPQSGVVKIDGMDVRGLTMSGLRRNIGVVFQEALLFNRSIAENLRVGKPDATDAELRLAAERAQALDFIDRNDLGFDTNAGERGRMLSGGERQRLSIARALLKDPPILILDEATSALDAVTEAKVNLALDEVMKGRTTFVIAHRLSTIRHATRILVFDNGKVIESGTFDELVAQRGRFAELARAQFMVQEEARAAVATATDDAPVRL
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFC4_ENCCU
Sequence: MDLLVNKYQPSEIQDIVGNEATMELVSLMIESRDMPHLLFTGPPGTGKTTCAKILARRLLGNKEGLLELNASDERGIDTVRTTIKSFAQRRVKDCEFKIIILDEADSMTTTAQQAMRRVMEIHSSECRFILICNVFTKIFEPIQSRCAILRFDRIEQSVILKRLKEISEGEGIRITAEALDLVVELSDGDMRQSLNILQACINSPGTVDQDYIIKIIGLPSPKRIEKVLQRLLKREVEEALEMFDEIWEEKFDPLDLINSFFRAAKNMESYELLKVIGLANLRISEGVNSRLQFYGMFWDILDMGSKRL
What is the function of this protein?
Component of ATP-dependent clamp loader (RFC and RFC-like) complexes for DNA clamps.  During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC.  The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit.  Dissociation of RFC from the clamp leaves the clamp encircling DNA.  Component of the replication factor C (RFC or activator 1) complex which acts during elongation of primed DNA templates by DNA polymerase delta and epsilon.  RFC has an essential but redundant activity in sister chromatid cohesion establishment (By similarity).
What are the official names of this protein?
Replication factor C subunit 4, Replication factor C4.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2BA_TRIST
Sequence: NLVQLGKMIFQETGKNPATSYGL
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that induces local edema a few hours after injection (5-10 ug) in the hind paw.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 CTs-G6, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_SYNSC
Sequence: MAATAPEPAFWDALGWQPSQAQRDQLEELQGLLQSWNERVNLTRLVNGDDFWIGQVFDSLWPLAGELQSANEPQHWIDVGTGGGFPGLAIAIALPQAQVTLLDSVGRKTAAVEAMASSLGLADRVGVRTERIETTGRDRHFRGSFDRAVARAVAAAPVVAEYLVPLLKTDGEALLYRGQWADSDAVPFNRALRLLAARLVEVQHRQLPSDRGTRHLLRVKPNGPCPRSYPRAVGTPSRDPLGS
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y189_ACISE
Sequence: MKKVHLIQADITAFAVHAIVNSANKSLLGGGGLDYVIHKKAGPLMKEECVRLNQEKGGCPTGQAEVTTAGNLPAKYLIHAVGPRWLDGEHNEPQLLCDAYSNALFKANEIHALTVSFPCISTGVYGFPPQKAAEIAIGTILSMLPQYDHVAEVFFICREDENYLIYKNILSNIDDPNIQILIS
What are the official names of this protein?
Macro domain-containing protein, ORF549.
Protein: PSF3_BOVIN
Sequence: MSEAYFRVESGALGPEENFLSLDDILMSHEKLSVRTEIPMPRLGAFFLDRSGGAETDNAIPEGTKLELPLWLAKGLFDNKRRILSVELPKIYQEGWRTVFSADANVVDLHKMGPHFYGFGSQLLHFDSPENADISHSLLQTFVGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQKGLNDFQCWEKGQASQLTASNLVQNYAKRKFTDMED
What is the function of this protein?
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks.  GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
DNA replication complex GINS protein PSF3, GINS complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the GINS3/PSF3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin.
Protein: CCA_ALIF1
Sequence: MKIYLVGGAVRDSLLNIDVKDKDWVVVGSTPQKMDSLGYQTVGQDFPVFLNPKTKEEYALARTERKSGQGYKGFTCYAEPDVTLEEDLLRRDLTINAIAQADNGELIDPYNGQQDIIDRTLRHVSDAFTEDPLRVLRVARFAARFHHLGFTVAPETMHLMKVLVDSGELSHLTAERVWQEWQKSLSSQHPEIFLSTLKECGALAIVLPELNALFGIPQPEKWHPEIDTGIHTLMVAQQAALLSQDLPTRFAAQVHDLGKGVTPESEWPSHKLHCHTGIKLIKRLCDRVRVPNDYRDLALLVCEHHSNIHRAAELRAQTFIKIFDKMDVWRKPERLAPILLCCQADHAGRLGLETQPYPQKKRFEAAFDAAKNVEVKDVVAAGFKGPEIREELSKRRIEAVKDKLNIK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: KIF12_MOUSE
Sequence: MEERGSPDGDPARNLEQGPEGSETPIQVVLRVRPMSTVELRRGEQSALHCSGTRTLQVSPDVAFRFGAVLDGARTQEDVFRACGVKRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQGEGVPVPPSLAGIMQRTFTWLLDRVQHLDSPVTLRASYLEIYNEQVWDLLSLGSPRPLPVRWTKARGFYVEQLRVVEFGSLEALMELLQMGLSRRRSSSHTLNQASSRSHALLTLHISRPTSQQVPPVDLGEPPVGGKLCFVDLAGSEKVAATGSQGQLMLEANSINRSLLALGHCISLLLDPQRKQNHIPFRDSKLTKLLADSLGGRGVTLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPGVKPPQQVENELLRLQEENRHLRFQLDQMHTTAPGAHGARMAWAQRNLYGMLQEFMLENERLRKEMRQLRSSRDLARAEQRVLAQQVHDLERRLLSACPLPQQGSTPVCPCRMVPAASCHALPPLCYCHHFCPLCRVPLAHWTCPRRECHMPQVLEPEAPGHISQSVWPPPWAPPPSPGSAKPPRERSQSDWTQTRVLAEMLMGEEVVPSAPPLSAGPSNMPYGLRGGSGIPNLTPRLETLTQQINSSLHLSQRQPQPSEDTQSPGQGLSSC
What are the official names of this protein?
Kinesin-like protein KIF12.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: BRKP4_PHYNA
Sequence: RPPGFTPFR
What is the function of this protein?
May produce in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
[Thr6]-bradykinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: CT5A_CONMR
Sequence: MRCLPVFVILLLLIASAPSVDARPKTKDDMPLASFHDNAKRILQILQDRNACCIVRQCC
What are the official names of this protein?
Conotoxin mr5a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP_STRP2
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_BURCH
Sequence: MSGERAKRFPLALEDLKRAPRKSEGRPGERQTAGAVPKAADKPAAVLKPVAVKPAAVRAPLPGIAAAKPATAPKPTALKPALPKPAAPSIAPAGAFALTSERVRERMVERLRANGVTDARVLDAMAAVPRHLFVDPGLATQAYEDSALPIGHQQTISKPSVVARMIELAMAGRTLERVLEIGTGCGYQAAVLSHVARDVYSIERIKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPSAAPFDAIVIAAAGLDVPQALLEQLAIGGRLVAPVGAQSGQHQVLTLVERVAHAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_NITMU
Sequence: MSLSLDDVKRVANLARIEISEDEARKALIQLSGIFGLIEQMQAVDVSAITPMSHAQDVMQRLRADGATEIDQRELFQSVAPQVEAGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: SPED_PHOLL
Sequence: MHKLKLHGFNNLTKSLSFCIYDICYAKSQADRDSYIAYIDEQYNANRLTEILSETCSIIGANILNIARQDYDPQGASVTILVSEEPMDPKDVDNTENPGPLPDSVVAHLDKSHICVHTYPESHPGGGICTFRADIEVSTCGVISPLKALNYLIHKLESDIVTMDYRVRGFTRDVNGMKHYIDHEISSIQNYMTEEVQSQYYMMDVNIYQENLFHTKMMLKRFDLNDYLFNATPEQLSEAEKQEITHLLKKEIQEIYYGRNLPTV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: IRC11_YEAST
Sequence: MTWMVKLLRQMISMQSQYGAALGATCLLHYLTTSLSIRFFFHDLTVRKHEVMPLGMDYYYLYAIGKDPSHPEIRGSVRKILEKYKTKADKANCALALEAISEHARSVYEYFGFKTYLVFQFGVGEVNSKGEPDPQGKGFTAYLMLYHKDADTIFHA
What are the official names of this protein?
Putative increased recombination centers protein 11.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1438_STAAR
Sequence: MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTFNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSVGVAHANVIEYVDKLKKVFNEAFHVDNYDINVTTPVISAHTGQGAIGLVVLKK
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein SAR1438.
Protein: LEXA_VARPS
Sequence: MQFAVKLTARQQQILDLIQSAIARTGAPPTRAEIANELGFKSANAAEEHLQALARKGVIELVSGTSRGIRLKGDALRSLNESRHREGGQFSLSLPGMSQLALPLIGRVAAGSPILAQEHVDQTYYVENTLFQRQPDYLLKVRGMSMRDAGIMDGDLLAVQATKEARNGQIVVARLGDEVTVKRLKRNKQVIELHAENPDYPTIVVQPGEPFEIEGLAVGLIRNTMLM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y475_BUCA5
Sequence: MFTKGGLGNLMKQAQQMQEKMAKIQEEIAQMEVTGEAGAGLVKVTINGAHNCRRVEVDPSLLQDDKDMLEDLAAAAFNDATRRISEVQKKKMSAISTGMQLPNGFNMPV
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BUAP5A_475.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ANFC4_TAKRU
Sequence: MNLSYLVACGLMITLLSVRMGAKPLSQAQQKSFRSLLGEELAEFLESEEKERRLDAVRSRLRLLRDLRMDTRARGVWARLLNDQPVPRRHKTGIKKGGSSRSGCFGHKMDRIGTISGMGC
What is the function of this protein?
Exhibits natriuretic and vasodepressant activity.  Has cGMP-stimulating activity.  May help to regulate body fluid homeostasis in a variety of aquatic environments.
What are the official names of this protein?
C-type natriuretic peptide 4.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRF_HAES1
Sequence: MINEIKKDTQQRMEKSLETLRTHIAKIRTGRAQPSLLDGIQVEYYGSPTPLRQLANVVAEDARTLAVTVFDRSLISAVEKAILTSDLGLNPSSAGTTIRVPLPPLTEERRRDLIKIVKGEGEQGKIAIRNVRRDANDQIKALLKDKEISEDEERKAQDEIQKITDTFVKKVDEILADKEKELLDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_TOLAT
Sequence: MKRTIILMLDSLGIGASADAVRFGDEGANTLGHIAQACVTGNADNGRKGPLTLPNLTRLGLAHACAASCGEFPAGLDASVTPIAAYGYARELSSGKDTPSGHWEMAGAPVLFDWGYFTDKQNSFPPELLDALVAQGNLPGYLGNCHASGTEILDRLGEEHMRSGKPIFYTSADSVFQIACHEETYGLDKLYELCKLARQLLEPYNIGRVIARPFVGSKAGEFKRTGNRHDYAVEPPMPTLLDRMKAAGGDVISIGKIADIYACCGITQQHKATGLDELWDMTLAQVKTAADQSIIFTNFVDFDSSYGHRRDVAGYAAALEYFDSRLPELLALLLPGDRVVLTADHGCDPIWTGTDHTREHVPVIFYGDTVQPQDLGMRDTFADIGQTIAAYHGLPVLDYGSNCLPEHH
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.