PharMolix/UniProtQA huggingface dataset:
Protein: PADI4_MOUSE
Sequence: MAQGAVIHVAPEQPTHAVCVVGTATPLDVRGSAPKGYTTFGITASPGVIVDVIHGPPVKKSTMGASKWPLDPELEVTLQVKAASSRTDDEKVRVSYYGPKTSPVQALIYITGVELSLSADVTRTGRVKPAQAGKDQSTWTWGPGGRGAILLVNCDKEDPQASGMDFEDDKILDNKDLQDMSPMTLSTKTPKDFFEKYQLVLEVPKAKMNRVRVFRATRGKLPSRYKVALGPQQFSYCLELPGGQHSTDFYVEGLAFPDADFKGLIPLTISLLDKSNPELPEALVFQDSVTFRVAPWIMTPNTQPPQEVYVCRVSDNEDFLKSLATLTKKAKCKLTVCPEEENIDDQWMQDEMEIGYIQAPHKTLPVVFDSPRDRGLKDFPVKRVMGPNFGYVTRKLYMSELTGLDAFGNLEVSPPVTVRGKEYPLGRILIGNSGYSSSESRDMHQALQDFLSAQQVQAPVRLFSDWLFVGHVDEFLSFVPARDKQGFRLLLSSPRACYQLFQELQSQGHGEATLFEGLKRKRQTINEILSNKKLRDQNAYVESCIDWNRAVLKRELGLAEGDIIDIPQLFKLAGNSRGNSKAQAFFPNMVNMLVLGKYLGIPKPFGPIIDGHCCLEEEVRSHLEPLGLHCTFINDFYTYHVYNGEVHCGTNVRRKPFTFKWWHMVP
What is the function of this protein?
Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance (PubMed:15339660, PubMed:32528174).  Citrullinates histone H1 at 'Arg-54' (to form H1R54ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci) (PubMed:15339660).  Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of 'Arg-54' of histone H1 (H1R54ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance (PubMed:24463520, PubMed:32528174).  Promotes profound chromatin decondensation during the innate immune response to infection in neutrophils by mediating formation of H1R54ci (PubMed:20733033, PubMed:23650392).  Required for the formation of neutrophil extracellular traps (NETs); NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (PubMed:20733033, PubMed:32528174).  Citrullination of histone H3 prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription (By similarity).  Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1 (By similarity).
What are the official names of this protein?
Protein-arginine deiminase type-4, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV.
What is the protein family that this protein belongs to?
Belongs to the protein arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils and neutrophils.
Protein: PHNW_PSEPG
Sequence: MSNAPILLTPGPLTTSIRTRQAMLVDWGSWDRDFNQLTASVCEQLLAIIDGSASHHCVPLQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGQRLAKICKVLGRPYSTFETAEDQPTTAADVDRLLAADPAVTHVALIHCETSTGILNPLPEIAQVIKRHGKRLIIDAMSSFGALPIDAREIPFEALIAASGKCLEGVPGMGFVFAEKTALAAAEGNAHSLAMDLHDQHAYMAKTGQWRFTPPTHVVAALHEALQQYNEEGGLPARHQRYADNCKTLLDGMAAIGLRSFLPAEIQAPIIVTFHAPNDARYQFKDFYERVKAKGFILYPGKLTQVETFRVGCIGVVGADGMQAAVNAVAQVLREMEVLDI
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: DCDB_BIFLD
Sequence: MLLSDRDILAAQSAGHISLDPWTPEMVQPASIDVRLDRYFRLFNNHAYTYVDPAENQGALTEQFEVAPDEPWILHPGEFALGSTWEYVKLDPSIAARLEGKSSLGRLGILTHSTAGFIDPGFEGHITLELSNVSTLPVKLWPGMKIGQMCFFQLSSPAEHPYGSKGTGSHYQGQRGPTPSRSYENFYRAHIDD
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: YEHW_ECOLI
Sequence: MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQESFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAVLAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRVRKVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIADRLFERLVQALSQHAK
What is the function of this protein?
Part of an ABC transporter complex involved in low-affinity glycine betaine uptake.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glycine betaine uptake system permease protein YehW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y807_OLEA2
Sequence: MLKPEWSRYIDLLHKEVVPALGCTEPVAVALAAAHAAATLGRTPDRIEVKVSGNLLKNGMGVGVPGTGTTGMNIAAAVGALGGDPQRGLEVLAGLTPEQAEAGRQMVAEGRVDVSVAQGAPLLYAEVTVTGGGHTARSVLVHEHSNIVRLERDGETVFSVPVQDLSQGGVEEKWPLTMAAIHEFATQAPYDAIAFILEAARLNEAIAVEGLAREYGLKVGRTIDENIRKHLMSDDVSTLAVKLTAAASDARMAGVSLPVMSNSGSGNQGITCTMPVVAFAKRLESSDEELARALIMSHLTSIHMKHRLGRLSALCGATVAAAAAGCGIVLLMGGGMEQVDRTIRNMVGNVAGMICDGAKTGCAMKVASAVSAGVQSAMLAMDGIGIDRREGIVEDDIELCIANLARLGSDGMQEADRVVLDIMVSKKP
What are the official names of this protein?
UPF0597 protein Dde_0807.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: LYT1_HOGCA
Sequence: IWLTALKFLGKHAAKHLAKQQLSKL
What is the function of this protein?
Forms pore that permeabilize the cell membrane.  Promotes efflux of calcium from synaptosomes, causes hemolysis, and dissipates voltage gradients across muscle membrane.  Potently inhibits the growth of bacteria, yeast and Leishmania.  Is lethal to lepidopteran larvae.  May function both in the prey capture strategy as well as protection from infectious organisms arising from prey ingestion.
What are the official names of this protein?
M-lycotoxin-Hc1a, M-LCTX-Hc1a, Lycotoxin I, Lycotoxin-1.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: QSEB_SALTI
Sequence: MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLELLLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGDA
What is the function of this protein?
Member of a two-component regulatory system QseB/QseC.  Activates the flagella regulon by activating transcription of flhDC (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein QseB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK11_DICDI
Sequence: MSNIQENENKETCNIKENENKEILKENFKNKEKQYFSSLRSPYSACRSVDCFKKLYTINEGAFGVVYCAQDKETEEIVALKKIKMEREREGIPITSVREIKVLMELKHDNIVQIKEIVLGKNINSIFMAMEFIDHDLRGLMEVIKKPFLPSEIKTLIQQLLNGVSYMHDNWVIHRDLKTANLLYTNKGVLKIADFGLAREYGSPLKPLSKGVVTLWYRAPELLLDTEIYTPAIDIWSVGCIFAEIISKEVLLQGSSEIDQMDKIFKLFGTPTEKSWPAFFKLPLAKYFNLTDQPYNNLKSKFPHITDNAFDLLNKLLELNPEARISASDALKHPYFFENPQPRDPLLMPTWPSSHKKT
What are the official names of this protein?
Cyclin-dependent kinase 11, Cell division cycle protein kinase 11, Cell division protein kinase 11, PITSVRE serine/threonine protein-kinase cdk11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: LGT_PROM4
Sequence: MEAYFATFRSPGPELLKVGFFTLRWYGLLIAFAVLIGLNLSNKLASIKGLSKNLINDLLPILVISSIIGARAYYVIFEWRNYSGSNFWSSIQAFGLTISIPTFIKVWQGGIAIHGALLAGTIAILIFCRLKQEDFWDVLDVLIPSVALGQAIGRWGNFFNNEAFGLPTDLPWKLFIPYPYRPEFFLDNNYFHPTFLYESIWNILLFLCLISLIRLSIKGKLKLPSGSLSCVYAIIYSLGRVWIEGLRTDPLCLGGVPPFCIGGIRIAQLISTILFGLGLLGLFWIYQRKKKLPSLGIIGRKHQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCAJ_ACIAD
Sequence: MSYHKLTRDQIAQRVAQDIPEGSYVNLGIGLPTKIASYLPADKDVFLHSENGLLAFGPPPAAGEEDPELINAGKEYVTMLEGGCFFHHGDSFAMMRGGHLDICVLGAFQIAANGDLANWHTGAPDAIPSVGGAMDLAVGAKKVFVTTDHVTKKGEPKIVAELTYPATGQKCVDRIYTDLCIIDVVPEGLKVIEKVEGLSFEELQRLTGATLIDATQG
What are the official names of this protein?
3-oxoadipate CoA-transferase subunit B, Beta-ketoadipate:succinyl-CoA transferase subunit B.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: DDL_BLOFL
Sequence: MKSKLRVGLVCGGCSLEHEVSLKSAIYIMKYINKRFFEVVVLWISKQGDWYIVENDDMHIDFFVNKENLHKCMPILMFSSGNRCFEYINNILSLDVIFPIIHGALGEDGSLQGLLRLMNLPYVGSDVLGSAICMDKDITKRLLRDSGLSITPFRTFLAHEKKKLKFLNFADMFGLPFFVKPVNQGSSIGVAKVNDDYSFHSALDIAFFYSHKIIIESCIAGRELECAVLGNNENPITSVCGEIIKKNDDFYTYCDKYVDHNSEIVIPAVLEKSVSSKIRSIAIRVFQILNCFGMARVDIFLFGKDRIIINEVNTLPGFTSDSMYLKLWQATGINISTLLTRLIMLALDRYYKYN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_STUS1
Sequence: MALAIYNTLSKAKEPFRPLEGNKVRMYVCGMTVYDFCHIGHARVMVAFDVVTRWLRHRGYDVTYVRNITDIDDKIIRRASENGEPFQALVERMIAAMHEDETRLNVLRPDVEPRATDHIAGMHTMIQTLIDKGFAYAPGNGDVYYRVGKFVGYGKLSRRKIEDLKIGARIEVDEAKEDPLDFVLWKGAKPGEPSWDSPWGPGRPGWHIECSVMSTCCLGETFDIHGGGPDLVFPHHENEIAQSEAATGKLYANAWMHAGAVRVDGEKMSKSLGNFFTIREVLEKYHPEVVRYLLVSSHYRSPINYSEDSLREAKSALERFYNGLKGLPEAQPAGGDEFVARFAAAMDDDFNSPEACAVLFEMIREVNRLREADLAAAAALAARLKVLAGVLGVLQLEPDAFLQAGAAGKVDAAEVEALIAARLAARAEKNWGESDRIRDQLTAMGVVLEDGKGGTTWRLAE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: TYRB_ECOLI
Sequence: MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQPHGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM
What is the function of this protein?
Broad-specificity enzyme that catalyzes the transamination of 2-ketoisocaproate, p-hydroxyphenylpyruvate, and phenylpyruvate to yield leucine, tyrosine, and phenylalanine, respectively.  In vitro, is able to catalyze the conversion of beta-methyl phenylpyruvate to the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin produced by Streptomyces hygroscopicus NRRL3085.
What are the official names of this protein?
Aromatic-amino-acid aminotransferase, ARAT, AROAT, Beta-methylphenylalanine transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERGI2_MOUSE
Sequence: MRRLNRRKTLSLVKELDAFPKVPDSYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVDKDFSSKLRINIDITVAMKCHYVGADVLDLAETMVASADGLAYEPALFDLSPQQREWQRMLQLIQSRLQEEHSLQDVIFKSAFKSASTALPPREDDSSLTPDACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHDSYNFSHRIDHLSFGELVPGIINPLDGTEKIAVDHNQMFQYFITVVPTKLHTYKISADTHQFSVTERERIINHAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIIGGIFSTTGMLHGIGKFIVEIICCRFRLGSYKPVRSVPFADGHTDNHLPLLENNTH
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 2.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: TVA29_HUMAN
Sequence: MAMLLGASVLILWLQPDWVNSQQKNDDQQVKQNSPSLSVQEGRISILNCDYTNSMFDYFLWYKKYPAEGPTFLISISSIKDKNEDGRFTVFLNKSAKHLSLHIVPSQPGDSAVYFCAAS
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 29/delta variable 5.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GLAH_SALTI
Sequence: MNALTAVKANTDDLAQRHTGFILAPSAQSPRLLALTFTADTTRQFLHQVAQWPVQALEYKSFLRFKIGKILDDLCGNQLQPLLIKTLLNRAQGALLISAEGIDDVAQAEEMVKLATAVAHLIGRSNYDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEVTDYVLMMKIDEQNMEGGNSLLLHLDDWEHLESFFTHPLARRVMRWAAPPSKNVSHDVWHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDALETSQNILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYAASHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: RS18_LEPBJ
Sequence: MEGKPQRKQNKYKKKVCRFTADPELAKQINYKNIELLERFITNRGKIIPRRITGTSARYQRVLAREIRKARSIGLLPYKVN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GATA_HELPS
Sequence: MITLKQALSLSQDELETLKNEIDAKVRASDLNAYIKAPSLNGASAKGVPILIKDNISVKGWEVTCSSKILEGYIAPYHASVIENLHQNSMAGFGLSNMDEFAMGSTTESSCYGITKNPRDKNRVPGGSSGGSAAAVAGGLAVAALGSDTGGSIRQPASYCGCVGLKPTYGRVSRYGLIAYCSSFDQIGPITQNVEDASILFDAISGHDSKDSTSANLKPTQTFKNLNREKRFKIAILRDHIKDASNEVQLAYENTLKALKEMGHEIVEKKMLDSHYQISIYYIISMAEASSNLARFDGVRYGRRAQNIKDLKELYLKSRSEGFGDEVKRRIMLGNFVLSSGYYDAYYLKAQQMRLMIKEQYNKIFEEVDLIFTPVAPTSAHLFNYHASPLEMYLSDIYTIGANLSGLPALSLPVAKDSLGLPIGMQFIAKAFDEQSLLDVSYALEQELDLKLD
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ARLY_BRUAB
Sequence: MSEQKSSNQMWGGRFASGPDAIMEEINASIGFDRKLYAQDIQGSLAHAAMLAKTGIIAAEDHKQIENGLKTIRKEIEEGKFTFSRKLEDIHMNIEARLAELIGPAAGRLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERIDESPLGAAALAGTGFPIDRHMTAKALGFREPTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIWSTPQFNFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMAGMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQSINPAITAEVFGYLTVEKSVKSRQSFGGTAPQEVRRQIRYWKKRIAKA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_BORHD
Sequence: MSRIGKLPIKIVDSVKVDINDNIVTVEGKRGKLSQEINSRIRVRVEDSNIIVERSLDDKQTRAFHGLYRSLIFNMVKGVSDGFSKSLTINGIGYRVEQQGTSLFFNLGYSTQFEYVIPEGVNIRLEGNTKIAVEGIDKCRVGQVAAEIRSLRVPEPYKGKGIRYDNEVSRRKVGKSGVKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FABV_SHEPC
Sequence: MIIKPKIRGFICTTTHPVGCEANVQEQITFTKNKGKIANGPKKVLVVGSSSGYGLSSRIAAAFGCDAATIGVFFEKPGTETKPGTAGWYNSAAFDKFAKAEGLYSKSINCDAFSHEAKQKVIELIKQDLGEIDMVVYSLASPVRRLPDSGEVIRSALKPIGETYTATAVDTNKDCIIEATVEPATEQEIADTVTVMGGQDWELWIKALSEAGVLANNCKTVAYSYIGTELTWPIYWHGALGKAKMDLDRAAKALNDQLSATGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMRQEGLHEGCMEQIYRMFSERLYRTDGAKPETDSDNRLRLDDWELRDDIQQHCRDLWPQVTTENLSELTDYREYKAEFIKLFGFGIEGIDYDADVNPYVEFDVIELQ
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: PSBL_PELHO
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: O16C_CONLI
Sequence: VLIIAVLFLTACQLTTAETYPRGQQRHHALRSTDKNSKLTRGCTPRNGFCRYHSDCCSNFCHTWAIMCL
What are the official names of this protein?
Conotoxin LvVIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_CAEEL
Sequence: MKINNSLLNFVNGMLVTLPSSKTLTLSWNFGSMLGMVLIFQILTGTFLAFYYTPDSLMAFSTVQYIMYEVNFGWVFRIFHFNGASLFFIFLYLHIFKGLFFMSYRLKKVWMSGLTIYLLVMMEAFMGYVLVWAQMSFWAAVVITSLLSVIPIWGPTIVTWIWSGFGVTGATLKFFFVLHFLLPWAILVIVLGHLIFLHSTGSTSSLYCHGDYDKVCFSPEYLGKDAYNIVIWLLFIVLSLIYPFNLGDAEMFIEADPMMSPVHIVPEWYFLFAYAILRAIPNKVLGVIALLMSIVTFYFFALVNNYTSCLTKLNKFLVFMFIISSTILSWLGQCTVEDPFTILSPLFSFIYFGLAYLMLFIFMSSKLLFK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain (PubMed:20971856).  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c (By similarity).  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis (PubMed:20971856).
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ZN134_HUMAN
Sequence: MTLVTAGGAWTGPGCWHEVKDEESSSEQSISIAVSHVNTSKAGLPAQTALPCDICGPILKDILHLDEHQGTHHGLKLHTCGACGRQFWFSANLHQYQKCYSIEQPLRRDKSEASIVKNCTVSKEPHPSEKPFTCKEEQKNFQATLGGCQQKAIHSKRKTHRSTESGDAFHGEQMHYKCSECGKAFSRKDTLVQHQRIHSGEKPYECSECGKAFSRKATLVQHQRIHTGERPYECSECGKTFSRKDNLTQHKRIHTGEMPYKCNECGKYFSHHSNLIVHQRVHNGARPYKCSDCGKVFRHKSTLVQHESIHTGENPYDCSDCGKSFGHKYTLIKHQRIHTESKPFECIECGKFFSRSSDYIAHQRVHTGERPFVCSKCGKDFIRTSHLVRHQRVHTGERPYECSECGKAYSLSSHLNRHQKVHTAGRL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 134.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AXE1_ASPTN
Sequence: MAPFSFILTVLLYALTCSARALGHAHALLPRAGSLEQVTDFGDNPTNVGMYIYVPNNLASSPGIVVAIHYSPEGTGTAEAYYTGSPYAQLAEQYGFIVIYPQSPYEGTCWDVSSQETLTHNGGGNSNSIANMVTWAISKYNADSSKVFVTGSSSGAMMTHQNVMAATYPELFAAATVYSGVPAGCFYSSSNQQDGWNSTCAQGQVITTPENWANVAKGMYPGYNGTRPKMQIYHGSVDTTLLPQNYYETCKQWAGVFGYNYDSPQQVQDNTPQSNYATTTWGDDLQGIFATGVGHTVPIRGDDDMAWFGFA
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone (By similarity).
What are the official names of this protein?
Probable acetylxylan esterase A.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_GEOSM
Sequence: MKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIAAAVRAFGGRVEMTSPTHETGTDRLAEVAAKIDADIVVNVQGDEPLIDPAMIDEAIRPLLDDPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSRSPLPFFRDKWNDLKDDAFVSGKLLCYKHVGLYVYRREFLPVFAGLKPTYLELAEKLEQLRVLENGYRIKIVETEFESIGVDTPADLDKVLERLKDR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.