PharMolix/UniProtQA huggingface dataset:
Protein: HS90A_HUMAN
Sequence: MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD
What is the function of this protein?
(Microbial infection) Seems to interfere with N. meningitidis NadA-mediated invasion of human cells.  Decreasing HSP90 levels increases adhesion and entry of E. coli expressing NadA into human Chang cells; increasing its levels leads to decreased adhesion and invasion.
What are the official names of this protein?
Heat shock protein HSP 90-alpha, Heat shock 86 kDa, HSP 86, HSP86, Lipopolysaccharide-associated protein 2, LAP-2, LPS-associated protein 2, Renal carcinoma antigen NY-REN-38.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Melanosome. Cell membrane. Mitochondrion. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: FLP01_CAEEL
Sequence: MTLLYQVGLLLLVAATYKVSAECCTPGATSDFCTVFSMLSTMEQNEVMNFIGENCDGDAEVALQKMEKRKPNFMRYGRSAAVKSLGKKAGSDPNFLRFGRSQPNFLRFGKASGDPNFLRFGRSDPNFLRFGKAAADPNFLRFGKRSADPNFLRFGRSFDNFDRESRKPNFLRFGK
What is the function of this protein?
Acts as a ligand for the npr-22 receptor in vitro.
What are the official names of this protein?
FMRFamide-like neuropeptides 1.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y231_MYCCT
Sequence: MKRTIKYLSFLGLIPFLSITTISCVKQAKENNNKNQLISQFKQLIFILNSFDLDNKKLESKIIKAIEKSDFNKISNINLELTIKFLTRIKNELETKTISQLNKNDKLDILTKIKVHLGSLNLIELVNIVDELVNKLNQKEEIKNTHKDKIEKNKDNIEDIDDSKLEILESKYIPNQHNYPDYVKNFKTVSAEEIYKELYDRTFSIKFLVKLKDGGLLSNGTGTGWLLDYHKYSNTNKYKMFIATNLHVLADFSNSLTDEQNKEFNYYDPSGNKVIGLGLGKADNVTDFSRKNNNSKSENNIANYYLNNQDFENYLKNDFWSVNKFSKGISEPKIVFGAVDFMKDRAIKNHYEALQKEAINYYNYKKNNNEINDDNKIAWNNFLNNKDIPIMIDFAVFEFDVDLDLVDYNLKSWISNAISGLDNYLDRLNKAPILPNQDKKISKYLQTTDYVSALFKKDKSEQNLYNAKDIYIAGYPTSQYSRSVWMQNNPIERNSSTLTSNWRSPTNDKTFAFANEVEEKAGTGLNFNIHDNYWHRVFATFYGYQYNINFSSLYYGASGSLAYNEFGQMIGIYNNVKSNVEFGDLLQSATIAPFLQSDNIKVGDNIIYAYNLIDGTDKTKYKYQKSSFRENLQKLYPNGFSDGLKSTKLFDDIFN
What are the official names of this protein?
Uncharacterized lipoprotein MCAP_0231, ORFA.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: JZ21C_CHIGU
Sequence: MKTSVLLVILGIAAITVQCTASESVEQDSLRTFVDTVLGWNAEMASEARCGGWMAKCADSDDCCETFHCTRFNVCGK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U14-theraphotoxin-Cg1a 3, U14-TRTX-Cg1a, Jingzhaotoxin-21.3, JZTX-21.3, Peptide F3-11.69.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 65 (Jztx-21) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RK33_OENGL
Sequence: MARGKDARVTVILECTNCVRGGVTKESTGISRYITEKNRHNTPGQLELKKFCPYCYKQTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK36_DRANE
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVA_DESRM
Sequence: MIAYIKGLLAADGPGWVVIDVNGIGYHVSIPSTTQLPALGHEVKLFTHMSVREDGIQFFGFAKEDEKECFLLLLNVAGVGPKVALAVVSHLPPSNLRSAIAIEDVNQLVKVPGVGKKTAQRILLELKDKLKGMAAVEHSTLQQSVITTGSGDEAVEALLALGYSQGEARDAVKKAQKSAPEEDLSALIKIALKELAPSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: YQGF_MYCBO
Sequence: MVPAQHRPPDRPGDPAHDPGRGRRLGIDVGAARIGVACSDPDAILATPVETVRRDRSGKHLRRLAALAAELEAVEVIVGLPRTLADRIGRSAQDAIELAEALARRVSPTPVRLADERLTTVSAQRSLRQAGVRASEQRAVIDQAAAVAILQSWLDERLAAMAGTQEGSDA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_SHEB8
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGEIHMRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: V042_FOWPN
Sequence: MKLFFYLLIVYKKYYSSGGDIETAYNCLISFRLLAVSYVLSSLILEHLGNRIDILEAVWVEDLVNSDPIISHTGANEISEIITSG
What are the official names of this protein?
Uncharacterized protein FPV042.
Protein: Y687_GEOSW
Sequence: MTHAHITSWLITVILFFIAVSLQRSGASKAKIVQMALRLFYIFTVITGGLLLHSIASISILYIIKAIVGLWLIGAMEMVLSGMKKGKNTNVAWIQWIVAFVLVLFLGFMLPLGFDLF
What are the official names of this protein?
UPF0344 protein GWCH70_0687.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_CERS4
Sequence: MANVVVVGAQWGDEGKGKIVDWLSERADVIARFQGGHNAGHTLVIDGKVYKLSLLPSGIVRPGKLSVIGNGVVLDPWHLVQEIAKLRADGVEISPQSLMIAENAVLILPLHGELDRARESQNSVAKIGTTGRGIGPAYEDKVGRRAIRVADLADEATLALRVDRLMVHHDALRRGLGIEPVDREALLAQLREIAPQVLPYAKPVWKVMNEMRKAGKRILFEGAQGALLDIDFGTYPYVTSSNVIAGQAATGTGIGPGAIGFVLGIVKAYTTRVGEGPFPAELQDADGERLGERGREFGTVTGRKRRCGWFDAVLVRQTCATSGVSGIALTKLDVLDGFETLKICVGYELDGERLDHLPIAADQQARCTPIFEELEGWSESTAGARSWADLPGAAVKYVRRIEELIQCPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_ACIBT
Sequence: MALLQIAEPGQSSAPHQHRIAIGIDLGTTHSLVATVLSGKPKVLNDVQNRRLLPSIVHYGDNTTHYGEEAKPFIIADPKNTIVSVKRFMGRSKADIKFQHPYELVGSENEMPAFETRAGRKTPVEISAEILKQLKARAEDSLQNPVNGAVITVPAYFDEAQRQATRDAAQLAGLNVLRLLNEPTAAAVAYGLDQESNLATDRNYVIYDLGGGTFDVSILRFSQGVFEVLATGGHTALGGDDLDRLIVKWAKKQLNIDVLSDEDYAVFIVAARQAKEQLSTQDSVELKLLEATLTLDRPTFESIIQVALDKTISVCKRVLRDAKLELTDIQNVVLVGGSTRSYAVQKAVREVFAQEPLCTINPDEVVAIGASITANQLIGNSQDGSLLLDVTPLSLGLETMGGLVERLISRNTAIPVARRQEFTTYQDGQTAMLIHVVQGERDLVEHCRSLGRFVLHGIPPMTAGQARIEVTFQVDADGLLTVSAREATSGVQAHIDIKPSYGLSEADTERLLIEGFQHAEEDKNLRHLKETKVEAERELEALEQALKVDADLLDEKQLEALNSAKGSLKAQLEGSDIQAIEQAVQQLKVHSDAFAALRMNRHIDHALKGTKLDDWSKSN
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GPMA_BACMK
Sequence: MIKLVLIRHGQSLWNLENRFTGWTDVDLSKNGLSEAREAGTILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMDLTWVPIHNSWKLNERHYGALQGLNKDETAKKYGDEQVHIWRRSIDVRPPALTEDDPRYEANNPRYKTLKKDEFPLTECLEDTEKRVVDYWHSEIVPSLKSGEKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDEKLRPIRHYYLSMDGEVPEGEIPKHISF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: EIF3C_CAEEL
Sequence: MSRFFHAKEDSDSDTSSSEDEVEDQKVNKSAKFRDDLDFMAGPEEDEKRVVRAQKDKKFDELKGIIKQNRDAKSNKDLNRLLTGFDSLAKAYDKSKTVFQRQNVANPRFYIRSLVEIEDYVNKLWDDKDAKSALSKNNAKALPPLRQKLKKYIKDQQLQDLVTDYRVNPDEDGYETPEDEDDDDFGEVSESKAEKSPGKPSEKAAVSDSDSDSDDDDSSNWSSEPESNSSDDEDSVTKMEQLRRYFLKKEFRVESKDDKKEKKKRVIRVKEAVEEDDDADWTPVNREKSVVHFDPKEEVTHDVMIKKLNEVMSARGKRTTDRNQHVANLRKLLEVSEEKELGLGINVKISFCIISALFELNAKISDHMEYETFMTTLQTVNSLLDLLIGTDRVKLSVTYAEEDENLKDDTQEYRIQGSILIAVQRLDGELAKILQNADCHSNDYIEKLKAEKDMCSLIEKAEKYVELRNDSGIFDKHEVCKVYMMRIEHAYYKYQDQNEEDAGKLMDYLCNKIYTLDDEKRLRQRAMLCHVYYLAVHDKWHRARDLLLMSHMQAIVDHSDVDTQILYNRTICQLGLCAFRHGFIREAHQGLSEIQNTQRAKELLAQAVGTRQHEKTAEQEKIDRSRQVPYHMHINVELMECVYLICSMLLEIPHMASCEFEMRRRMLSRSFHYQLKQSEKASLTGPPENTREHVVAASKAMLNGDWKKCQDYIVNDKMNQKVWNLFHNAETVKGMVVRRIQEESLRTYLLTYSTVYATVSLKKLADLFELSKKDVHSIISKMIIQEELSATLDEPTDCLIMHRVEPSRLQMLALNLSDKLQTLAENNEQILEPRTGRGGYQGPGSWFPGRNERQGDKQKGSGGYQGERRGGQGQDGKRGNWGSQGGQQRRHPQKPRAF
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_LACCB
Sequence: MPKRQDIHKILVIGSGPIIIGQAAEFDYSGTQACLALREEGYEVVLVNSNPATIMTDTEIADRVYIEPLTVEFVSQILRKELPDAILPTIGGQIGLNLAMKLSNTGILDELGIELLGTKLTAIDQAEDRELFKNLMQKLHEPVPESAIANNIEEAQQFADKIGFPVIIRPAFTMGGTGGGIANNEKELAEIAENGLNLSPVTQVLVERSIAGYKEVEFEVMRDAADSAIVVCNMENFDPVGVHTGDSMVFAPTQTLTDKEVQMLRDAALKIIRALKIEGGCNVQFALDRNSFKYYVIEVNPRVSRSSALASKATGYPIAKMAAKIAVGLHLDEIKNPVTKKTWAEFEPALDYVVTKLPRFPFDKFENGDRTLGTQMKATGEVMAIGRTLEESLLKAVRSLEVGLIHPERPAFAKLSDDELSKQIIQANDERLFYLAEAFRRDYTIEEVAELSKMNPFFLDKIKHIVELERELAAHKADLGLLAEVKRYGFADEEIAKLWGLHADQVRQMRKEQKILPVYKMVDTCAGEFASDTPYYYSTYESSTESVKSDKPSVLVIGSGPIRIGQGVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSIADKLYFEPLTLEDVLNVIDLEQPEGVIVQFGGQTAINLAEPLANRGIKILGTSVEDLNRAEDRDLFDQVIKSLKLPQPEGGTATDKAGALAVADKIGYPVLVRPSYVLGGRAMEIVHDATELDNYIDRAVSVSHDHPVLIDHYLVGKECEVDCISDGDTVVLPGIMEHIERAGIHSGDSMAVYPPQTFSQDIIDQITDATIKLSRTLNCIGLMNVQFIIHDGKAYVIEVNPRASRTVPFLSKVTNIKLAQVATLAILGLSLKEQGFETGLLPNQSGIHVKSPVFSFSKLNHVDSLLGPEMKSTGEVMGSDTTLAKALYKAFEAAGMHLPQFGRALITVKDADKAEATALAKRFREVGYQLVATSGTAKAFEKAGITVSTIEKLDSGQETILEDIANRKIQLVINTMSADKKVSSDGFRIREAAIEHGVPLMTSLDTAGAILKVLELQAFSISPIKS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: UPPP1_BURTA
Sequence: MDWILICKALALGIVEGLTEFLPVSSTGHLIVAGSFLRFHPEQAKTFDVVIQFGAILAVCWEYRRRIVDVVTGLPAQREARRFTMNVVIATLPAIALALLFEKTIKSVLFAPVPVAVALVVGGAVILWVEGRQRERGKPSRVQSIDALTPLDALKVGLAQCFALIPGVSRSGSTIIGGMLFGLERRVATEFSFFLAIPVIFGATLYETAKDWHAFNVDSIGLFAIGLAAAFVSAFACVRWLLRYVASHDFTAFAWYRIVFGLFVLLVGYSGWIEWI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPA1_PEA
Sequence: MGLLCSKSNRYNDAKAEENAQTAEIERRIELETKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEAELKSYLPVVHANVYQTIKLLHDGSKEFAQNDVDFSKYVISTENKDIGEKLSEIGGRLDYPRLTKELAQEIESIWKDAAIQETYARGNELQVPDCTHYFMENLQRLSDANYVPTKEDVLLARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVSAVIFCVAISEYDQTLFEDENKNRMMETKELFEWVLKQQCFEKTSFMLFLNKFDIFEKKILDVPLNVCEWFKDYQPVSTGKQEIEHAYEFVKKKFEESYFQSTAPDSVDRVFKIYRTTALDQKVVKKTFKLVDETLRRRNLFEAGLL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-1 subunit, GP-alpha-1.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: YCJF_ECOLC
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDPB_SALPA
Sequence: MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSVLTTLLTLAMVTGQIAGSALFTGVISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKKTAFARRLRAPRHDAQADNVPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIACSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASDFIPARGVDERALADAAQLASLADETPEGRSIVILAKQRFNLRERDMQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVESNGGHFPADVEQNVENVARLGATPLVVVEGARVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNVMGLHSPNSAILSAVIFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLGGLVVPFIGIKVIDVLLTLLGLA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDA2_KLULA
Sequence: MTSSIKITDNSRELNGPVSREKLSSILNEIFNKDEPIPSSVELVLAQLNELSSKHKFIVNVTKLNANNVNTADFSVDSYIGSSWNDKSDGAFHYQIPLGSGQPDTKRILLVSVYWILL
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: DEF_NOVAD
Sequence: MAIREIIEVPDPRLKQVSVPVEKFDDELKTLVEDMFETMYDAPGIGLAAIQVGVPLRVLVIDLQPDDPDAEPVACDHDGHHHHHQPTKKEPRVFINPEILDPSEEYSVYQEGCLSVPEIYAEVERPATIRARWQDLDGKVHEEQMEGLMATCLQHEMDHLEGVLFIDHLSRLKRNMALKKLEKLRKAA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YIDE_ECOSM
Sequence: MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVGHFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIIGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSYAMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIRTINIRVENPNLHDLAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQEVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGDISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVPGFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHNX_VIBVY
Sequence: MNKSPIQAVIFDWAGTIVDFGSFAPTSIFVEAFKQGFDFEIDLEEAREPMGLGKWDHIQAVGRIPAVDKRWNEKFGRSMISEDIDAIYAAFMPLQKAKVADHAEPILNAIEVVNGLKDKGIKIGSCSGYPREVMDVLIPVAADYGYQPDYVVATDDLPQGGRPAPFMALKNVIELGVSDVKACVKVDDSAPGIFEGHNAGMWTVGLLLSGNEAGLTFEEYQAADEATLEKAREKARAKLLKSSPHYLIDTIADFPEVVADIERRLAAGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: FBL26_ARATH
Sequence: MDRISNLPNEIICHIVSFLSAKEAAFASILSKRWRNLFTIVIKLQFDDSVKNEGSLKDFVDGVLALPTSSRVRSCSLECRREFDPTHYDDFNRCICALLKRGILDLKLDICAGRRYSLPLEVFTCKTLVKLELGSDFGGFVVDLVPEDAFLPALETLLLNYIRFKDLRRCAFEKLLSACLVLKELVIHNMEWERWKWSGNISSPTLERLTISHVDLYECEFTRINLDTPNLTYLELSDAVPDDYPIVNLDSLVEVKLDLTLMVDHKYHGYVDDNDTISSNPTNLINGLRNVEIMNLQSPNTFQAFSYFHEAIPVFKNLYHLTITNNDTVIGFCWEFLPFVIKKCPNLKTLVIDGPLHYNEDRPKSVCHCLSGYSFLLSCPLEVLQITDYSGTPGEVEQLKHFLEKLSGLKLVKLHSLTRFGSDKKKLLMLPRASSKCKIKHYDSLENALLPSLKTLILDSVKFYDRCGCCAFQKLLSACPVLVESVMRNLEWEDWEWSGCASSQTLERLTIDHRYWAEHNLESFTFDTPSLTYLDYNAHVPGSYPTVNLDSLVEAKLNLGFTTDLVEDDDDPFTSDPTNLIKGLRNVEILRLWM
What are the official names of this protein?
F-box/LRR-repeat protein At3g58980.
Protein: GCSH_ACIC5
Sequence: MAYPANYRYTREHEWIEIDGKTGTVGITDYAQNSLGDIVFVESPKVGDKIEKGKVFGSVESVKAVSDLYAPVSGTVTAVNEELANAPEKINTDAHTAWIMKIELSDAAEAESLLDATAYEAFVKEETGH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: GM3C_CONCN
Sequence: QGCCNGPKGCSSKWCRDHARCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This synthetic toxin blocks both voltage-gated sodium channels and nicotinic acetylcholine receptor (nAChR).  Inhibits the skeletal muscle rNav1. 4/SCN4A (IC(50)=1. 3 nM) and the brain rNav1. 2/SCN2A in a long-lasting manner.  A low inhibition is also observed on neuronal mNav1. 6/SCN8A and mNav1. 7/SCN9A.  Modestly blocks nAChR alpha-3/beta-2 subtype (IC(50)=450 nM) (partially reversible) and, to a lesser extent, alpha-7 and alpha-4/beta-2 subtypes (reversible).  In vitro, decreases twitch tension in mouse hemidiaphragms (IC(50)=150 nM), and displays a high blocking effect in mouse extensor digitorum longus muscles (IC(50)=46 nM).
What are the official names of this protein?
Mu-conotoxin CnIIIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: U2D2B_RAT
Sequence: MALKRIHKELNDLAQDPPAQCSAGPVGEDMFHWQATIMGPNDSPYQGGAFFLTIDFPTEYPFKPPKVEFTTRIYHPNVNSNGSICLDILRSQWSPALTISKVLLSISSLLCDPNPDDPLVPEIAQIYKTDRDKYNRTAREWTQKYAM
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Mediates the selective degradation of short-lived and abnormal proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6.  Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection Plays a role in early maturation of the testis.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D2B, E2 ubiquitin-conjugating enzyme D2B, Ubiquitin carrier protein D2B, Ubiquitin-conjugating enzyme E2(17)KB 2B, Ubiquitin-conjugating enzyme E2-17 kDa 2B, Ubiquitin-protein ligase D2B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: PYRF_SALNS
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLHDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: ZN506_HUMAN
Sequence: MGPLQFRDVAIEFSLEEWHCLDAAQRNLYRDVMLENYRNLIFLGIVVSKPNLITCLEQGKKPLTMKRHEMIAKPPVMYSHFAQDLWSEQSIKDSFQKVILRRYEKCRHDNLQLKKGCESVDECPVHKRGYNGLKQCLATTQRKIFQCDEYVKFLHKFSNSNKHKIRDTGKKSFKCIEYGKTFNQSSTRTTYKKIDAGEKRYKCEECGKAYKQSSHLTTHKKIHTGEKPYKCEECGKAYKQSCNLTTHKIIHTGEKPYRCRECGKAFNHPATLFSHKKIHTGEKPYKCDKCGKAFISSSTLTKHEIIHTGEKPYKCEECGKAFNRSSNLTKHKRIHTGDVPYKCDECGKTFTWYSSLSKHKRAHTGEKPYKCEECGKAFTAFSTLTEHKIIHTGEKPYKCEECGKAFNWSSALNKHKKIHIRQKPCIVKNVENLLNVPQPLISIR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 506.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.