PharMolix/UniProtQA huggingface dataset:
Protein: DSG3_CANLF
Sequence: MTWLLFRTSGALAILMVLILVHGELRIETKGQHGEDETAIQGRRRYKREWVKFAKPCREREDNSRRNPIAKITSDFQATQKITYRISGMGIDQPPFGIFVVDKNTGEINITAIVDREETPSFQITCHALNVLGQDVEKPLILTVKILDVNDNAPVFSQSIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRHTGEVRTLTNSLDREQVSSYRLVVSGADKDGEGLSTQCECSIKVKDVNDNFPMFKESQYSAHIKENTLTSELLRFQVIDWDEEFTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVQFSIAVKNKAEFHQSVISQYQVKSTPVTIQVVNVKEGIAFHPASKTFTVRKGISSKKLVNYVLGTYQAIDEDTNKAASYVKYVMGRNDGGLLFIDPKTAQIKFVRNIDRDSTFIVNKTITAEVLAIDENTGKTATGTIYVEVPGFNENCPTVVLEKKAICSSLRSVVVSARVPDNKYTGPYTFSLEEQSLKLPVVWSITTLNATSALLNAQQQLSPGEYTISLTVTDSQDRQCETPESLTLEVCQCDNRDICRSSNGNKDYERLDGKRPSGRLGSAAIGLLLLGLLLLLLAPLLLLTCDYGVGPIGGVTGGFIPVPDGSEGTIHQWGIEGAQPEDKEITNICVPPITTSGADFMENSEVCTNTYAGGTVVEGASGMELTTKLGAATGSGAAAGFGATAGFGAATGLGIGSAGQSGTMRTRHSTGGTNKDYGEGAISMNFLDSYFSQKAFACAEEDDVQEANDCLLIYDNEGMGAPSSPVGSLGCCSFIADELDDSFLDSLGPKFKKLAEISLGIDDEAKQSQPLSKASLSGMESCGYSLEVQQPESVRGQTLLGSQGASALSASSSVLQSATSIPNPVQHGSYMVTETYSASGSLVQPTTTVLEPLLTQNVTVTERVICPISNVSGNLQTPMELRGSRNMICTEDPCSRLI
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).
What are the official names of this protein?
Desmoglein-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: SINR_SALTY
Sequence: MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQDESYTISGAVNVHLSSNNLLSVLNLVLEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD
What is the function of this protein?
Probable regulatory protein.  Its target is not known.
What are the official names of this protein?
Probable HTH-type transcriptional regulator SinR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: MATK_ARALP
Sequence: MEKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFLENTDYDKKYSSLIVKRLILRMYEQNRLIIPTKDLNQNSFLGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFQGKQLKKSYNLQSIHSILPFLEDKLAHFNYVLDVLIPYPIHLEILVQILRYWVKDASSLHFFRFCLYEYCNCKNFYIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSPSYEVLFERIFFYGKIQHFFKVFVNNFPAILGLLKDPFIHYVRYHGRCILATKDTPLLMNKWKYFFVNLWQCYFSVWFQSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKATWTDSSDFDILNRFVRICKNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKXKSTVCAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PREU6_PREIS
Sequence: MSNSTRDYPISAAFFCPQSRAPPAEYLHALYSFLSQNTLGKAFLRHIASLDEVWPIFSEARDDILRLPDARQNINVLVDWAKGGSSTPIAEARSGVIALPSVFIVQLGQYFRYLEANRLSHGDFIGQLKDIGGVHGYCGGAAAALSVACAADETQLIDHAAVLLRLFVGIGCCIEAVDDWTTTESTVIACRLKYEGQGDELCSRFPEPKSISITGNARTLSELFDYAVGLGLPTHKMEITGKAHNPENAELAKDFINLYRRTPALQLPPTFKLQATVRSNRTAEKLTNEGIIEDMITMIIASQCDWNTLLTRVAEDMKVSGRPFHKMVSFGMNDCVPVTPFNRQRLKTTKFEAHVLIEPLKPSRISAAQYPTFSDDAIAITGASLRLPGANNLDELWDLISKGTDCHREIPKDRFDPHNIYRTSQSGFSKAQKYFGNFLEDIKGFDRAYFSMGVREAANIDPQQRLLLELAVEALEASGYLANHVREAGDPVGCFVGASFIEYLENTGAHPPTAYTAPGTIRAFLCGRLSYYFGWTAPAEVIDTACSASMVAINRAVKSIQAGECEMALAGGVNLITGMNNYLDLAKAGFLSPTGQCKPFDQSGDGYCRSDGAGFVVLKKLSQALVNGDPIMGVIPSIETNQGGLSGSLTVPSSTALQALYKRVLSKSGLEPAQITYVEAHGTGTQAGDPIEVESVRAVLGDPTRAHSLSLGSVKGNIGHCETGAGVAGLLKVLAMIKHGGIPPLASHKALNPKIPALETHHMEIAKQLKPWDVPLRAAFVNSYGAAGSNAAVICVEPPPVVTDGSSLIGTEPQKVTLPVIVSGATRKSLVLNARALASYLSQDGSHLSIHDVAFTVNQRRKRNRFCAEVSGTDLPSLVQSLRAVDSPSFESPGKSKPVVLVFSGQNTNAVALDRTIYDTYPVFKAYIDACDSEIVKLGFPSIMEAIFQKEPISTAVALQGSIFAMQYACARSWIDAGLKPRAIIGHSFGELTALAVSGALSLADSLKLVTCRGHLIDTKWGEERGGMLVIHADVATVERFQSRFKAQHDGAELEIACYNSPTTTVVAGPVAYMDAAEQMLATDPDFQGLRKLRIVTSNAFHSSLSDPILADLDSMADTLTWNEPSIPLEACTSEGLASIKEWSASRHTRGSVYFTKAVERIEGRLGACIWVEAGLDSAIIAMARKASSKPDSQVFQSVSTKAGATSFIDGIVNNLWRQGVPLSHLNALSATVKPNPVWLPPYQFEREQHWTEHIDRATEASQASTTSDTIQSTPTQTVQSPPKLISRLASLQYQINTQCERFQKITEGHAVLYEPLCPASLYMECVVMALQELAGDLGSRTLDFENLDFHAGLGLQTDRRVLLDLEEARPHSWTFKVQSTKAGSSRSLLHCSGRVILTESSVPTTFQRLVDGPRSRLDQDKDAEKLMSSRAYGLFSNIMTYSEFLKPISSIILRENESLATIKLPPNQPGLHESTAWKRCDAVFLDGFISSSGLLLNSSSVVQSGHVLIAVGVERAILTAAFQASLASSWQAYATFTMVGETHALCDVFACTPDGEVVAMMTGVRFNKMEISKLAKSLSSVNASSPTGGRTQPPAAPKTQAQPMASRPSPTPLQVSFATAEPAAPEPVQQSTAALARNDIGPVLKSLISNYTGLIEEDVSEDSPLVDLGLDSLSSVEFASEIGTKFGVTLDADTVGDLTLHSLCQRLSGTSNVVSQKMSETPAAAPVKELIETVPSPIVTFSSPVSNSITSVLKSLLGSYTGLQEEDMPDDVPLIDLGLDSLSSVEFASELNDKMGADIDSAVVADMTLSALEQQLGASATPPSTTGSSTPGDISTAATTPYATGASTPDYLVHGNKPSISNGVVAAKDSYQVKTVEYKRVSGVPIHADIYVPLVQRVSPMPLALMIHGGGHMTLSRKAVRPTQAKYLLSHGFLPISIDYRLCPEVNLIDGPIADVRDAYVWACQNLGTHLAEHSISVDGGRVVVVGWSTGGHLAMSLGWSLEEAGVPPPKAVLSFYAPVDFESGELDNQKNPALPKPRMTLDQITKALPRTPVTQYGASSTDETNLGWLHPGDPRSELLLHVFHSDIGLPLILHGLPISGSGRPSPSLVASISPLARLRNGSYTIPTFIIHGTKDVIAPYAAAERFVKIMSEKGVKSGFLSLSGTGHVFDVTMKPDSKGWEDKVKPGLDFLIQNA
What is the function of this protein?
Non-reducing polyketide synthase; part of a gene cluster that mediates the biosynthesis of a yet unidentified natural product (Probable).  The first step in the pathway is performed by Preu6 that condenses 2 acetyl-CoA starter units with 6 malonyl-CoA units to produce lecanoric acid (LA), also known as orsellinate depside, an intermediate that has significant antifungal activity against the plant pathogen Botryosphaeria berengeriana (PubMed:35602042).  The biosynthesis probably occurs via the formation of 2 orsellinate intermediates fused together by the C-terminal thioesterase (TE) domain that finally releases lecanoric acid (Probable).
What are the official names of this protein?
Non-reducing polyketide synthase Preu6, NR-PKS Preu6, Lecanoric acid synthase.
Protein: VG23_BPML5
Sequence: MAENDDAVLTAAVGYVYVGAAGTAAPTPALLKTIDLSKPETWTGATGWTSVGHTSRGTLPEFGFEGGESEVKGSWQKKKLREITTEDPIDYVTVLLHQFDEQSLGLYYGPNASETPGVFGVKTGQTNEKAVLVVIEDGDMRLGHHAHKAGVRRDDAIELPIDDLAALPVRFTYLDHEDELPFSWINEDLFNVPEVPEG
What are the official names of this protein?
Major tail protein Gp23, Major coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: GCSH_RHORT
Sequence: MSKLYFTEDHEWVSVDDDGIGTIGITDYAQKQLGDVVFVELPEIGREIERGGDAAVVESVKAASEVYSPVSGEVVEANDSLPEAPGQVNTDALGDGWFFKVRLSEPAELDELMDQEAYDAFVGELD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SOFIC_SHEON
Sequence: MEWQAEQAYNHLPPLPLDSKLAELAETLPILKACIPARAALAELKQAGELLPNQGLLINLLPLLEAQGSSEIENIVTTTDKLFQYAQEDSQADPMTKEALRYRTALYQGFTQLSNRPLCVTTALEICSTIKSVQMDVRKVPGTSLTNQATGEVIYTPPAGESVIRDLLSNWEAFLHNQDDVDPLIKMAMAHYQFEAIHPFIDGNGRTGRVLNILYLIDQQLLSAPILYLSRYIVAHKQDYYRLLLNVTTQQEWQPWIIFILNAVEQTAKWTTHKIAAARELIAHTTEYVRQQLPKIYSHELVQVIFEQPYCRIQNLVESGLAKRQTASVYLKQLCDIGVLEEVQSGKEKLFVHPKFVTLMTKDSNQFSRYAL
What is the function of this protein?
Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
What are the official names of this protein?
Protein adenylyltransferase SoFic, AMPylator SoFic.
Protein: PHMD_PHANO
Sequence: MSKSKDPIFFSTGGLDNFISPKMRPLNGTAGEQWEFDGVSDDAKLAFVFGFYRDPNYAILGSGNLRVSVEMAWPNGSRFAQVDYPTDNIIEECDWGTRGIWRSNDFNYTFEITADMKRARVGMHTPQVTGIVSMTSTSQPRYPDGRTYPSENSTSEALPYFHFVEPIPVARAHVDMTILGEKFAWDGLGGMERLWGAFSWFTCLQGMNVIRILAGPYSLSMLSFTSNIKKGREYPSIALFDNGEPVFSSQNTEESDVNDYFSFTKTYDGKVTGTLRDKVTGYELELVSPGRQLHWTFLIDHANLAFEYILGRGTGGSGFSAWVNGGRMGREQFKGIALTEALTFPKKSPLFRPQYSED
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of the mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities (PubMed:31815421).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS phmA, assisted by the enoyl reductase phmE, that are responsible for fusion of the leucine precursor and the polyketide backbone to produce a 2-pyrrolidone intermediate (PubMed:31815421).  The polyketide synthase module (PKS) of phmA is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the leucine precursor (PubMed:31815421).  Because phmA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase phmE (PubMed:31815421).  Reduction by the hydrolyase phmG, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase phmD then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring cytochrome P450 monooxygenase phmB, the FAD-linked oxidoreductase phmC and the short-chain dehydrogenase/reductase phmF, are further required to afford the final products, phomacin D and phomacin E (PubMed:31815421).
What are the official names of this protein?
Diels-Alderase phmD, Phomacin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.
Protein: GVPL_DOLFA
Sequence: MSIPLYLYGIFPNTIPETLELEGLDKQPVHSQVVDEFCFLYSEARQEKYLASRRNLLTHEKVLEQTMHAGFRVLLPLRFGLVVKDWETIMSQLINPHKDQLNQLFQKLAGKREVSIKIFWDAKAELQTMMESHQDLKQQRDNMEGKKLSMEEVIQIGQLIEINLLARKQAVIEVFSQELNPFAQEIVVSDPMTEEMIYNAAFLIPWESESEFSERVEVIDQKFGDRLRIRYNNFTAPYTFAQLDS
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpF/L.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: CATA_SOLME
Sequence: MDLSKYRPSSAYDTPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYHLIEKLATFDRERIPERVVHARGASAKGFFEVTHDVSHLTCADFLRAPGVQTPVICRFSTVVHERGSPESIRDIRGFAVKFYTREGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQENWRILDFFSFLPESLHTFAFFYDDVCLPINYRHMEGFGVHAYQLINKAGKAHYVKFHWKPTCGVKSMTEEEAIRVGGTNHSHATKDLYDSIAAGNYPEWKLFIQIMDPEDVDKFDFDPLDVTKTWPEDILPLMPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGVYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCAHHNNHRDGAMNFMHRDEEVDYLPSRFDPCRPAEQYPIPSCVLTGRREKCVIPKENNFKQAGERYRTWEPDRQDRYINKWVESLSDPRVTHEIRSIWISYLSQADKSCGQKVASRLLVKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: YFCR_ECOLI
Sequence: MTGGVMSQKFVVGAGLLVCSVCSLSAMAGSKPVDLILRVLVDAPPPCSIKGSQVEFGNMIADNVDGTNYRQDAKYTLNCTNSLANDLRMQLKGNTSTINGETVLSTNITGLGIRIENSADNSLFAVGENSWTPFNINNQPQLKAVPVKASGAQLAAGEFNASLTMVVDYQ
What is the function of this protein?
Part of the yfcOPQRSUV fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.  Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.
What are the official names of this protein?
Uncharacterized fimbrial-like protein YfcR.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
Protein: TRMFO_PROM3
Sequence: MSSLPTVLVIGAGLAGSEAAWQIAQAGVPVRLIEMRPIKQSPAHYSSEFAELVCSNSFGALSSDRAAGLLKEELRRLGSIVIRTADSHAVPAGGALAVNRASFSASLTKELSAHPLITIERHEQEHLPGEGQITVLATGPLTSELLAENLRTFTGRSECHFFDAASPIIEGESIDLTLAFRASRYDKGDADYMNCPMDKGQYLAFREALLNAEQAELKEFDKESAKFFEGCLPIEELARRGEDTMRYGPLKPIGLWDPRWGDLNDRDVRRSKRAYAVVQLRKEDHEGRLWNLVGFQTNLKWSEQKRVLKMIPGLHQAEFVRFGVMHRNTFLEAPQLLEPTLQFSKRSNLLAAGQITGTEGYTAAVAGGWLAGSNAARLAMGLNTITLPSTTMIGALTHFVSDSDCFRDRKGEFQPMPANFGLLPELAERIHAKRERYGAYRDRALTMLEEAQQQWGMSKAPVQIGSS
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINY1_HUMAN
Sequence: MEYHQPEDPAPGKAGTAEAVIPENHEVLAGPDEHPQDTDARDADGEAREREPADQALLPSQCGDNLESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPETQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
What is the function of this protein?
Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins.  Has exodeubiquitinase activity and has a preference for long polyubiquitin chains.  May play a regulatory role at the level of protein turnover.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase MINDY-1, Deubiquitinating enzyme MINDY-1, Protein FAM63A.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
Protein: GYP7_CANGA
Sequence: MSIELLFCKSQVYIHPTKNLQDNVSGYLLITHQSNSETITSSTISWIPENSLNEEDINFLNNAETRNINEKILRLPVSSRKLNTLLGSGSFLSSNWQFTIPVLSLYSVQFKLPNTWWYGSCILYSKSPRETESIPVLYFHDDLCPSTISKQKELNRSFDPFNNSNEMYWGGQDFKDALGSIVELKRVESEPTFWLVNATLEDLRNFSSANLKSSEEKPSSSKDDGVTKLKEDAWQKWESTKWSLMSQFADITAKTGSFVGSLIKKHPVVQLVERNKNNYYVQKMLKNPKVVEIQDDFDSAKIYLAKWALSVKEEAERYQEGSYDNPYRRILVSEFGLTGNEDVSFTEEELNRAMERNHPMTKQKWNSLFDSEGRLTVTVNEVKDYIFHGGLADDATRKEVWPFLLGVYPWDSSEDERKQLRKALHDEYMELKQKWVDREVNLDNDEEEYWKDQLFRIEKDVKRNDRNIDIYKYNTSDNLPFPEDTAPTTDDDDSIKNPNLKKLADILTTYNIFNPNLGYVQGMTDLLSPLYYIIRDEETTFWCFTNFMERMERNFLRDQSGIRDQMLALTDLCQLMLPRLSAHLQKCDSSDLFFCFRMLLVWFKREFNYDDIFNIWEVFFTDFYSSQYQLFFMLAILQKNSSPIVNNLQTFDQVIKYFNDLNSKMNWRDLMVRSELLFIQFHKTADLLARRQEQLIPENSGHDTSDIEGGTEPKTQSYISEHLQTLLSKEVIIQKENTRTKDSIK
What is the function of this protein?
Most effectively accelerate the intrinsic GTPase activity of YPT7.  It is also active, but to a lesser extent, on YPT31, YPT32 and YPT1.  YPT6 and SEC4 (By similarity).
What are the official names of this protein?
GTPase-activating protein GYP7, GAP for YPT7.
Protein: ACCD_OLIPU
Sequence: MEKSWFNLMFSKGELEYRGELSKAMDSFAPSEKTTISKNRFIYDMDKNFYGWGERSSYSKNVDLLVSSKDIRNFISDDTFFVRDSNKNSYSIYFDIKKKFFEIDNDFSDLEFFFYSYCSSSYLNNSSKGDNDLHYDSYIKDTKYNCTNYIKSCIDSYFRSYICIDSNFLSDSNNSNESYIYNFICSESGKIRESKNYKIRTNRNRSNLISSKDFDITQNYNQLWIQCDNCYGLMYKKVKMNVCEQCGHYLKMMSSERIELSIDPGTWNPMDEDMVSADPIKFHSKEEPYKNRIDSAQKTTGLTDAVQTGTGQLNGIPVALGVMDFQFMGGSMGSVVGEKITRLIEYATNQRLPLILVCSSGGARMQEGSLSLMQMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASFGMLGDIIIAEPYAYIAFAGKRVIEQTLKKAVPEGSQAAESLLRKGLLDAIVPRNLLKGVLSELFQLHAFFPLNKN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: BTUB_ECOL6
Sequence: MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDHPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQPDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGLPLVDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNIIIGHGNIGAGVDWQKQSTAPGTAYVEDGYDQRNTGIYLTGLQQVGDFTFEGAGRSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGSYGNPNLNPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLXGSYTF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: TI173_ARATH
Sequence: MDTKKKSKEHGLYRIVNAIGYAFGAGAVGGSVYHFVRGAYNSPIGARYVGGTQAASMNAPRLGGTFAVFGGLLSTFDYALVRIRKKEDPWNSIVAGAATGGVLSIRKGVVAASTSAVMFGFFLAVLNPPFGSK
What is the function of this protein?
Essential component of the TIM17:23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Links the inner and outer membranes (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM17-3.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL22_PPWBP
Sequence: MNVKAIAKQMPITPRKTRLVADLIRGKNIKEAQAILMFTPKSASPIVLKLLKSAIANATNNFSLDDKNLYVKEIFVNEGLRLTRLFPRAKG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: A1KA2_LOXAP
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDSSANPEYTYHGVPCDCGRTCTKWEHFNEFLKGLRKATTPGDSKYHEKLVLVVFDLKTGSLYDNQASDAGKKLAKSLLQNYWNNGNNGGRAYIVLSIPNLAHYKLITGFKEALTSEGHPELMDKVGYDFSGNDDIGDVANAYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSSGYINKVHYWTVDKRQSTRDALDAGVDGIMTNYPDVIADVLNESAYKAKFRIASYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LapSicTox-alphaIB1aii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_CVH22
Sequence: MATVKWADASEPQRGRQGRIPYSLYSPLLVDSEQPWKVIPRNLVPINKKDKNKLIGYWNVQKRFRTRKGKRVDLSPKLHFYYLGTGPHKDAKFRERVEGVVWVAVDGAKTEPTGYGVRRKNSEPEIPHFNQKLPNGVTVVEEPDSRAPSRSQSRSQSRGRGESKPQSRNPSSDRNHNSQDDIMKAVAAALKSLGFDKPQEKDKKSAKTGTPKPSRNQSPASSQTSAKSLARSQSSETKEQKHEMQKPRWKRQPNDDVTSNVTQCFGPRDLDHNFGSAGVVANGVKAKGYPQFAELVPSTAAMLFDSHIVSKESGNTVVLTFTTRVTVPKDHPHLGKFLEELNAFTREMQQHPLLNPSALEFNPSQTSPATAEPVRDEVSIETDIIDEVN
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the alphacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: GPMI_RHOPA
Sequence: MQSRRPVMLVILDGWGWREDPADNAVLQAKTPTFDALWTNGPHAFLRTSGKSVGLPNGQMGNSEVGHLNIGAGRVVMQDLPRISDAIANGEIERAPGLVAFIDKLKASGGTCHLMGLVSPGGVHSLQDHACALAKILAKAGVKTVLHAFTDGRDTPPKSAVDDIVRLRAELPPNVPIATVSGRYYAMDRDNRWERVSKAYGVIADADGPRFADANAVIADGYAAGVNDEFIVPAVIGDYQGMRDGDGVLCFNFRADRVREILAALLDSAFAGFPRKQVKQIAAAAGMTQYSTALDALMGTIFPPQSLVNGLGQVVADAGLHQLRMAETEKYPHVTYFLNGGEEVPYPGEDRIMVPSPKVATYDLQPEMSAPELGDKAVAAIESGKYDLIVLNFANPDMVGHTGSLPAAIKAVETVDTQLGHIVAAIRKAGGALLVTADHGNCEMMRDPETGGPHTAHTTNPVPVLLVGDNGPLADGQLSDLAPTLLKLMELPQPAEMTGKSLIG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: ISPDF_BARBK
Sequence: MSIAAIILAAGRGSRAGSLQNGPKQYRFLGREPVICHTIRCFLQHPAITNIILVIHPDDYQICANAIADLKDHLTIIEGGETRQISTLQGLRALKNVKPNYVHIHDGARPFIGNELLEQIHTSINHKEGILPVLSVSDTLKYVSNTHHVLETIPRTNLYRAQTPQCFPFELILAAHEKAMQSHKQDFTDDSAIAEWFGIPIRTIPGDPNNIKITWPADLETARSYLLKGMQIFPDIRTGNGYDVHSFEDGHYITLCGIKIPFEKKLNGHSDADVALHALTDALLATQGAGDIGTHFPPSDPQWKNASSEIFLHHAIEIIKKAEGRIANVDITLIAEKPKIGPYRHIMTENLMKILKISTDRISIKATTNEKLGFIGREEGIAALATATVIYPGEIPK
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: SCL1_ARATH
Sequence: MVEQTVVREHIKARVMSLVRSAEPSSYRNPKLYTLNENGNNNGVSSAQIFDPDRSKNPCLTDDSYPSQSYEKYFLDSPTDEFVQHPIGSGASVSSFGSLDSFPYQSRPVLGCSMEFQLPLDSTSTSSTRLLGDYQAVSYSPSMDVVEEFDDEQMRSKIQELERALLGDEDDKMVGIDNLMEIDSEWSYQNESEQHQDSPKESSSADSNSHVSSKEVVSQATPKQILISCARALSEGKLEEALSMVNELRQIVSIQGDPSQRIAAYMVEGLAARMAASGKFIYRALKCKEPPSDERLAAMQVLFEVCPCFKFGFLAANGAILEAIKGEEEVHIIDFDINQGNQYMTLIRSIAELPGKRPRLRLTGIDDPESVQRSIGGLRIIGLRLEQLAEDNGVSFKFKAMPSKTSIVSPSTLGCKPGETLIVNFAFQLHHMPDESVTTVNQRDELLHMVKSLNPKLVTVVEQDVNTNTSPFFPRFIEAYEYYSAVFESLDMTLPRESQERMNVERQCLARDIVNIVACEGEERIERYEAAGKWRARMMMAGFNPKPMSAKVTNNIQNLIKQQYCNKYKLKEEMGELHFCWEEKSLIVASAWR
What is the function of this protein?
Probable transcription factor involved in plant development.
What are the official names of this protein?
Scarecrow-like protein 1, AtSCL1, GRAS family protein 4, AtGRAS-4.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.