PharMolix/UniProtQA huggingface dataset:
Protein: HISZ_SYMTH
Sequence: MSTPVTRTQVPDGVRDRLPSEAAAMRRLSARLDNVFRAWGYREVSTPVIEYLEAVAAGAANWGRREDLYQFFDRKGRTLALRPDMTTPIARLMATRLADEPLPLRLSYFAPVFRHRELRAGATSEIWQAGVELVGAPGEAADAEVISLACAAVRAADLTGFRIGLGHVGVVEGLFESAGVDPQAAAVLKEAMVARDLVAFEQGVARAGLSGERAERLLALVHFHGSYAEAVARFGGVGGRVAEALQHLGRVLEVLEALGVAEQVNLDLGLVRSLGYYTGVVFEGYLPGIGAPVLGGGRYDNLVAEFGRPLAATGFALEVDRLLMAQEQQGALAAEPGLDAVIACPPGQEAAAMAWAARLRAQGLAVEVDFLDRTGEELAAYARARAAARVLRPGVPSIH
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_HUMAN
Sequence: MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S13, Small ribosomal subunit protein uS15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACP_AZOSB
Sequence: MENIEQRVKKIVAEQLGVNESEIKNESSFVDDLGADSLDTVELVMALEEEFECEIPDEEAEKITTVQQAIDYVNAHLKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOHB_BUCAI
Sequence: MNLLLNYELFLAKIITFIIISISILILFYTIIKRKKNIQSKIKITLLQDNYKNVKNKILLSTMKNVEKKIWFKKQKEKNKKELLLKNNKKKLFVLDFKGDVYANEVVGLREEISAILLVANKHDEVLLRLESSGGVIHGYGLAASQLNRLRQKGIRLIVSVDKIAASGGYMMACVADYIVSAPFAIIGSIGVVGQIPNFNKLLKKCNIDFELHTAGDYKRTLTMFGNNTESTRKKFCDELNTTHKLFKSFIKEMRPSLDIEDVSNGEHWFGTIALEKKLVDQIGTSDDILISKMEEYTLLRIQYIYRKKILERFTASVTHNLSETLLKIFFYKNYL
What is the function of this protein?
Possible protease.
What are the official names of this protein?
Probable protease SohB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DOLK_BOVIN
Sequence: MTRECAPPTPGSGAPLSGSVLAEAAVVFVVVLSIHAAVWDRYSWCAVALAVQAFYVQYKWDRLLQQGSAVFQFRMSANSGLLPASVVMPLLGLVMKERCQAAGNPYFERFGIVVAATGMAVALFSSVLALGITRPVPTNTCVISGLAGGVIIYIMKHSLSVGEVIEVLEALLIFVYLNMILLYLLPRCFTPGEALLVLGGISFMLNQLIKRSLTVVESQGDPLDFFLLVVVVGMVLMGIFFSTLFVFMDSGTWASSIFFHLMTCVLGLGVVLPWLHRLIRRNPLLWLFQFLFQTETRVYLLAYWCLLATVACLVVLYQNAKRSSSESKKHQAPTITRKYFHFIVVATYIPGIILDRPLLYVAATVCLAVFIFLEYVRYFRIKPLGHTLRSLLSLFLDERDSGPLILTHIYLLLGMSLPIWLVPRPCTQKGSLGGARALVPYAGVLAVGVGDTVASIFGSTMGEIRWPGTKKTFEGTMTSIFAQIISVALILIFDSGVDLNYSYAWILGSISTVSLLEAYTTQIDNLLLPLYLLILLMA
What is the function of this protein?
Catalyzes CTP-mediated phosphorylation of dolichol, the terminal step in de novo dolichyl monophosphate (Dol-P) biosynthesis.  Dol-P is a lipid carrier essential for the synthesis of N-linked and O-linked oligosaccharides and for GPI anchors.
What are the official names of this protein?
Dolichol kinase, Transmembrane protein 15.
What is the protein family that this protein belongs to?
Belongs to the polyprenol kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PDXD1_BOVIN
Sequence: MDASLEKKIADPTLAEMGKNLKEAMKMLEDSQRRTEEENGKKLLSGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEQPQSTRIQNIGEQGHISLLGHSLGAYISTLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNRKPVLYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGKLPLLLVANAGTAAVGHTDKIGRLKEVCEQYGIWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTPGPWLGLPAVPAVTLYKHDDPALTLVSGLTSNKPADKLRALPLWLSLQYLGLDGIVERIKHACQLSQRLQESLKKVNHIKILVEDELSSPVVVFRFFQELPGSDPGLNAIPAPSAAASAVGRERHSCDALNRWLGEQLKQLVPMSGLTVMDLEVEGTCVRFSPLMTAAVLGTRGEDVDQLVACVQSKLPVLTCTLQLREEFKQEVEATAGLLYVDDPNWPGIGVVRYEHANDDKSSLKLDPEGEKIHAGLLKKLNELESDLTFKMGPEYKSMKSCIYIGMASDDIDISELVETIAVTAREIEEDSRLLENMTEVVRKGIQEAQVQLQKANEERLLEEGVLRQIPVVGSVLNWFSPVQASQKGRTFNLTAGSLESTEHTYVYKVQGSGVTPPQTPTGTRTKQRLPGQKPFKRSLRGSDAISETSSVGHIEDLEKMEQSSGGQEASEANSHERHPEAPAPPEAEPPGALQDGAQGLQDDRPQVEEPESLR
What are the official names of this protein?
Pyridoxal-dependent decarboxylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: DFA1_NOSS1
Sequence: MVALTEDTQANANIGRLTVQTVEIADETTAIRCLDWDRERFDIEFGLRNGTTYNSFLIKGEKIALVDTSHRKFEKLYLEIVAGLIDPNTIDYLIVSHTEPDHSGLVKDILQLAPNITIVGAKVAIQFLENMVHQPFKSLQVKSGERLDLGNGHSLEFVSAPNLHWPDTILTYDHKTGILYTCDVFGMHYCDDQTYDENFFAIEEDFKYYYDCLMGPNARSVLAALKRIENLAIKTVATGHGPLLQVHISEWLGRYKNWSLEQAKTETLVALFYAEDYGYSEHLVHILGHGCTKTGVAVELIDLNTAEPQEVRELVTQASGLVIAMPSQYSLTAQAALNTILAAVHHKQAIGLLESGGGEDEPVFPLRNKFQELGLVEAFPPILIKEAPAQTTEQLCEEAGTDIGQWLTRDRTIKQIKSINTDLEKALGRISTGLYIITTKKGEIQGAMFASWVTQASLNPLGVAIAVSKERAIESLMQVGDHFVLNVLEEDNYQGLMKHFLKRFAPGADRFAGIKTYPATDGSPILAESLAYTECEITSRMDCGDHWIIYSTVHVGRVANVHAMTAVHHRKVGNHY
What is the function of this protein?
Mediates electron transfer from NADH to oxygen, reducing it to water.  This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins (By similarity).
What are the official names of this protein?
Putative diflavin flavoprotein A 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavodoxin reductase family.
Protein: NOG2_CRYNV
Sequence: MGKGKNHDRKANPGFGKVKSKTGTSTGEFTLKRVKGENFYRDAKSASRVKMLNGGKAVRDRDGKIVEAAAFQKGEKEAEPGRVKPDRRWFGNTRVISQSALDHFRTALKEQKADPYSVLLKRNKLPMGFGSRKNRKQRPHIVETEPFGNTFGPKAQRKRPRLDIGKGNGTADLADIYHPTTSTAREPIYAKGTSRRIWGELYKVLDSSDVVIHVLDARDPLGTRCKPVVEYLRKEKAHKHLVYVLNKVDLVPTWVTARWVKHLSLSAPTIAFHASINNSFGKGSLIQLLRQFSVLHSDKKQISVGFIGYPNTGKSSIINTLKKKKVCTVAPIPGETKVWQYITLMRRIYLIDCPGIVPVSAKDSDTDTVLKGVVRVENLATPAEHIPALLERVRPEYLERTYGLEHVEGGWHGEEGATFVLTAIAKKSGKLLKGGEPDQEAAAKMVLNDWIRGKVPFFVAPPTKPESGADAHVSSATTEKVQEQEQKELAEEKETKEMLEEQERSLGKVLGIKRVKGVEQPISKIVTMTKFLGDDARRYVEEEEVDVDDVDKEMAEEDEDEDEDDDDDVEESGEDQEEEELAWDDVFPEEAAGVDAADGEEVEEDDEEEEGDEDDEDVPSAKQLGKRKAIDSDEEEQTAIKAKRMTTNKQKASNFYTHANVKNRNRDRKVPKNPGKRSRGDDEPTGKKAKKRR
What is the function of this protein?
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
What are the official names of this protein?
Nucleolar GTP-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DNLJ_PECAS
Sequence: MNAVALRVAELRRVLRHHEYKYHVEDAPEIPDIEYDKLMQELKALEADHPELVTSDSPTQRVGAAPLAAFEQVRHEVPMLSLDNVFDEESYLAFSKRIGDRLKNGDDLTFCCELKLDGLAVSLLYEEGILVQAATRGDGTTGENITSNIRTVGAIPLRLEGENIPRRVEVRGEVFMKHGGFEKLNEEARRTGSKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLEGGELPASHWERLMQFKAWGLPVSDRIKLCTGPAEVLDFYRQVEQTRSSLGFDIDGVVVKVDSLALQERLGFVARAPRWAVAFKFPAQEQLTWVRDVEFQVGRTGAITPVARLEPVAVAGVIVSNATLHNADEIERLGLQIGDRVIVRRAGDVIPQIVGIVESERPETVQPIVFPAACPVCGSDVERVEGEAVTRCTGGLICGAQRKEALKHFVSRRALDVEGMGDKIIDQLVEKEYVKTPADLFRLSAGIMTGLDRMGPKSAMNLVNALEKAKSTTLARFLYALGIRDVGESTAANLAAHFGSLETLFAADEDALLEVPDVGKIVAAHVRHFLEEEHNQTVIRELTDPAGINIYWPEVKVVNAEEIDSPFAGKTVVLTGSLSILSRDEAKDRLTALGAKVSGSVSKKTDMVIAGEAAGSKLAKAQELGIPVIDEAEMIRLLNNHGDVSTL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RRP36_CANDC
Sequence: MSRGKTIRPSYYDEDESSQDELEYTLNKGRSNIGSESDSDVDEMSKISFGALNRAQTKLNKNNQKHKPSSWKENINNSSEEFFDSDSDSDGPPEETSSKDTKKKKNKHAPSESSSKRPVSRIRDIPGLPSRKQQTLHTDIRFDAAYGKADLIKARKDYAFLDEYRKQEIASMESLLKDKKNKLNDDEREEIKLQLQSLKSRMDTLKNRDLENNILSNYKKQQMESFKEGKVNKPYFLKRSDKRKILQKAKFDSMKPKQREKAMERKRKKRLGKEFRQLEFRPTNR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ITPA_MOUSE
Sequence: MAASLVGKKIVFVTGNAKKLEEVIQILGDNFPCTLEAQKIDLPEYQGEPDEISIQKCREAARQVQGPVLVEDTCLCFNALGGLPGPYIKWFLQKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVLLFRGQTSGQIVMPRGSRDFGWDPCFQPDGYEQTYAEMPKSEKNTISHRFRALHKLQEYFSVAAGAGDH
What is the function of this protein?
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVA_STAEQ
Sequence: MTVRTKVSTKDIDEAYLRLKNIVKETPLQFDHYLSQKYNCNVYLKREDLQWVRSFKLRGAYNAISVLSNEEKNKGITCASAGNHAQGVAYTAKKLNLKAVIFMPVTTPRQKINQVKFFGDSNVEIVLIGDTFDHCLAQALNYTKQHKMNFIDPFNNVYTIAGQGTLAKEILNQAEKEDKTFDYVFAAIGGGGLISGVSTYFKAHSPHTKIIGVEPTGASSMYQSVVINHSIVTLENIDKFVDGASVARVGDITFDIAKDKVDDYVQVDEGAVCSTILDMYSKQAIVAEPAGALSVSALEQYKKQIENKTIVCIVSGGNNDINRMKEIEERSLLFEEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKTSQNTGTVIIGIQLKHHDDLIQLKDRVCQFDPSNIYINENKMLYSLLI
What is the function of this protein?
Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction.  The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate).  Both intermediates are unstable and short-lived.  The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia.  In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
What are the official names of this protein?
L-threonine dehydratase biosynthetic IlvA, Threonine deaminase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: Y1436_STUS1
Sequence: MLIPHDQLESDTLTRLIEDFVTRDGTDNGDETPLDTRVARVRRALDRGEAVIVFDADSQQCQLALKRDVPREWLD
What are the official names of this protein?
UPF0270 protein PST_1436.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: ERPA_BURMS
Sequence: MNAVTESAATTEMPAPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVLNKNGVVLLVDAMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: BGAL_ECOLI
Sequence: MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: FLPA_ARCFU
Sequence: MKELMRNVYLLDDTLVTKSKYGSHYGEKVFDGYREWVPWRSKLAAMILKGHRLKLRGDERVLYLGAASGTTVSHLADIVDEGIIYAVEYSAKPFEKLLELVRERNNIIPLLFDASKPWKYSGIVEKVDLIYQDIAQKNQIEILKANAEFFLKEKGEVVIMVKARSIDSTAEPEEVFKSVLKEMEGDFKIVKHGSLMPYHRDHIFIHAYRF
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: METXS_ACIBY
Sequence: MSFPADSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADKSNAILICHALSGHHHAAGYHHEDDKKAGWWDSCIGPGKAIDTNKFFVVALNNIGGCSGSTGPTSPNPENDNRPYGPDFPLVTVRDWVKTQAMLSDRLGISVWYAVVGGSLGGMQALQWSVDYPDRLQKCVVIASAPKLSAQNIAFNEVARQSILSDPDFHHGRYLEKDSYPKRGLILARMVGHITYLSEEAMKQKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYGHSLTEAMSKTKCQFLIVSFTTDWRFAPSRSQEIVDALITNQKPVSYLDIDAEQGHDSFLFPIPLYVKTLRAFLGGEEHLKSTSLEAS
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKS2_ARATH
Sequence: MGQIQYSDKYFDDTFEYRHVVLPPEVAKLLPKNRILSESEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQEHQAQIAK
What is the function of this protein?
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
What are the official names of this protein?
Cyclin-dependent kinases regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the CKS family.
Protein: CRGA_MYCMM
Sequence: MPKSKVRKKNDFTVKPVSRTPVKVKVGPSSVWFVALFIGLMLIGLVWLMVFQLAAVGSQAPAALNWMAQLGPWNYAIAFAFMITGLLLTMRWH
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXS_SALA4
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKDRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVMGLISTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPGYSKIFGDWLCETAAKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQVIHDVAIQKLPVMFAIDRAGIVGADGQTHQGAFDLSYLRCIPDMVIMTPSDENECRQMLFTGYHYNDGPTAVRYPRGNAQGVALTPLEKLPIGKGLVKRHGEKLAILNFGTLMPEAAKVAEALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWQA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RS6_BURP1
Sequence: MRHYEIVFIVHPDQSEQVPAMIERYKSTITSHGGQIHRVEDWGRRQLAYMIEKLAKAHYVCMNIECDQTTLDELEHAFKFNDAVLRHLIVKMKKAETGPSPMMKEVQREEAKKAAAAQPTEAQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y1574_STAES
Sequence: MNDKWYRHIIGARTIKTGLATFFTSLFCMLLNLTPIFAILTAIVTIEPTAKASLKKGYKRLPATVIGALFAVVFTYVFGDQSPLSYALSATFTILICTKLNLQVGTTVAVLTSVAMIPSIHEAYVFNFFSRLLTALIGLVTAGLVNFIILPPKYYHQLEEQLALSEKKMYRLFYERCNELLLGKFSSEKTSKELSKLNIIAQKVETLMSYQRDELHYHKNEDNWKLLNRLTNRAYNNRLFISHLSNIIYLPKHTSIAFDANEKIALINISNSINGIIQKGSFARQKKSIATLKSSVKQMDEFDQNQMKSTLIYEILLIYKILDSRYAK
What are the official names of this protein?
UPF0421 protein SE_1574.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRR_BACVZ
Sequence: MNQKAVILDEQAIRRALTRIAHEMIERNKGMNDCILVGIKTRGIYLAKRLAERIEQIEGNPVTVGEIDITLYRDDLTKKTSNEEPLVKGADIPADITDQKVIVVDDVLYTGRTVRAAMDALVDVGRPSSIQLAVLVDRGHRELPIRADYIGKNIPTSKAEKVMVQLSEVDQTDMVAIYENE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: INU2_ARTGO
Sequence: MANTVYDVTTWSGATISPYVDIGAVINQIIADIKANQTSQAARPGAVIYIPPGHYDLLTRVVVDVSFLQIKGSGHGFLSEAIRDESSTGSWVETQPGASHIRVKNTDGNREAFLVSRSGDPNVVGRLNSIEFKGFCLDGVTDSKPYSPGNSKIGISVQSDNDSFHVEGMGFVYLEHAIIVKGADAPNITNNFIAECGSCIELTGASQVAKITNNFLISAWAGYSIYAENAEGPLITGNSLLWAANITLSDCNRVSISSNKLLSNFPSMVALLGNCSENLIAANHFRRVSGDGTSTRFDDLFGLVHIEGNNNTVTGNMFSFNVPASSISPSGATPTIILVKSGDSNYLATNNIVSNVSAMVVLDGSTTATRIIYSAKNSQLNAYTTSYTLVPTP
What are the official names of this protein?
Inulin fructotransferase [DFA-I-forming], Inulin fructotransferase [depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming].
Protein: RNPH_CLOP1
Sequence: MRSSGRKKEQIRPVKITRNFTKYAEGSVLIEVGDTKVLCTASIEEKVPPFLKGSGEGWITAEYNMLPRSTQSRKQREINKLKIDGRTMEIQRLIGRALRSAVDMKALGEKTIWIDCDVLQADGGTRTTSITGSFVALVDAVNKLHQKKPFNVYPIRHFVSAVSVGIVGEEKVLDLCYEEDHVAKVDMNVVMTEEGEFIEIQGTGEAGPFSRKELDELLNLAEKGAKQMIQAQKDALKTDSLWIGTGRE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: KPRS2_LACLA
Sequence: MVYSDSHLKLFALNSNPGLAEKISQFTGVPLGKLSSKQFSDGEIMINMEESVRSQDIFIVQSTSCPVNDHLWELLIMIDACKRASARTINVVIPYFGYARQDRTATSREPITAKLVADMIVKAGADRLLTLDIHAVQVQGFFDIPVDNLFTVPLFADYYRKSGLFGDDVIVVAPKNSGIKRARSLAEYLESAIAIVDYEDDDKNRENGYVIGNVSGKKVILIDDILNTGVTFANAANVVREAGASEIYAVASHGLFTSGAADVLEKVDIKEILVTDSVVTNHRKPLNVKYLSAAEYLASAILRIHEGRPVSPLFEHEKPQD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_VIBA3
Sequence: MEVIVIGSGVIGLTSAWYLAKEGHTVTVIDRQDSSGKETSFANAGQISYGYSSPWAAPGIPLKAMKWLTQEHAPLKVKPSLSPELVAWATKMLANCNEAKYAMNKSRMLRVANFSRECLTHLRTSEDLAYEGRQKGTLQVFRSEKQLDAIQQDMKLLTESGIEHSLFDVDQCLSVESGLADVKDKLVGGLYLPHDETGDCHQFCLTLTEKAKQLGVRFVFDTEVVSLNHQNRAIETITTTQGEFKADAYVVASGSYSRELLKQVDLSIPVYPVKGYSLTLPIVNVDKSPTSTVMDETYKVAMTRFDDRIRIAGTAELAGFDYLIPEKRKATIDMVIKDLFPQAGDFSKAEYWTGLRPMTPDGTPIIGKTPIKNLFTNTGHGTLGWTMACGSGKILASVVSGSASDIKSDDLSIHRYL
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ATOX1_ARATH
Sequence: MSQTVVLRVAMTCEGCVGAVKRVLGKMEGVESFDVDIKEQKVTVKGNVQPDAVLQTVTKTGKKTAFWEAEGETAKA
What is the function of this protein?
Plays an important role in copper homeostasis by conferring tolerance to excess of copper and subclinical copper deficiency during vegetative stage.  Can complement the yeast mutants atx1 and sod1.
What are the official names of this protein?
Copper transport protein ATX1, Copper chaperone ATX1.
What is the protein family that this protein belongs to?
Belongs to the ATX1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SPUE_PSEAE
Sequence: MQHSIGKTLLVAALATAIAGPVQAEKKSLHIYNWTDYIAPTTLKDFTKESGIDVSYDVFDSNETLEGKLVSGHSGYDIVVPSNNFLGKQIQAGAFQKLDKSKLPNWKNLDPALLKQLEVSDPGNQYAVPYLWGTNGIGYNVAKVKEVLGDQPIDSWAILFEPENMKKLAKCGVAFMDSGDEMLPAALNYLGLDPNTHDPKDYKKAEEVLTKVRPYVSYFHSSKYISDLANGNICVAFGYSGDVFQAAARAEEAGKGIDIQYVIPKEGANLWFDLMAIPADAKAADNAYAFIDYLLRPEVIAKVSDYVGYANAIPGARPLMDKSVSDSEEVYPPQAVLDKLYVSAVLPAKVLRLQTRTWTRIKTGK
What is the function of this protein?
Spermidine-binding protein probably required for its uptake into cells.  Binds spermidine with high affinity (KD=14. 3 nM).  Does not bind putrescine, cadaverine or spermine.  Spermidine binding induces large inter-domain conformational changes.  Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence.
What are the official names of this protein?
Spermidine-binding periplasmic protein SpuE.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm.