PharMolix/UniProtQA huggingface dataset:
Protein: LEC5_VIGUC
Sequence: MASSTVSVVLSLFLLLLTQAYSADIQSFSFKNFNSSSFILQGDATVSSSKLRLTKVKGNGLPTLSSLGRAFYSSPIQIYDKSTGAVASWATSFTANIFAPNKSSSADGIAFALVPVGSEPKSNSGFLGVFDSDVYDNSAQTVAVEFDTFSNTDWDPTSRHIGIDVNSIKSIRTASWGLANGQNAEILITYNAATSLLVASLVHPSRRTSYIVSERVDITNELPEYVSIGFSATTGLSEGYTETHDVLSWSFASKLPDDSTTEPLDIASYLVRNVL
What is the function of this protein?
Metalloglycoprotein, containing Ca, Mg, Mn, and Zn and the carbohydrates galactose, glucosamine, mannose, and fucose.  It agglutinates erythrocytes of blood group A1.
What are the official names of this protein?
Lectin DB58.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: CLPP_NITWN
Sequence: MRDPVETYMNLVPMVVEQTNRGERAYDIFSRLLKERIIFVTGGVEDNMSMLVVAQLLFLEAENPKKEISMYINSPGGVVTSGLAIYDTMQFIRPPVATLCTGQAASMGSLLLAAGEKDMRHALPNARIMVHQPSGGFQGQATDIMLHAQEILSLKKRLNEIYVKHTGQTYQAIEDALERDKFLTADMARDFGIVDKVIDKRAEDPAAPKASS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REG6_PYRFU
Sequence: MRGILDDIDKKIIEILQKDGKVPLREISKITGLAESTIHERIKRLRESGVIKKFTAVVNPEALGYNILAFILIKVKAGKYSEVASKLVKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDMVGSIEGVEGTHTMIVLKVHKETTELPVK
What is the function of this protein?
DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes.
What are the official names of this protein?
HTH-type transcriptional regulator FL11, Feast/famine regulatory protein FL11, FFRP FL11.
Protein: NRDR_CORU7
Sequence: MLCPSCRCEDSRVVDSRVVEGGIAIRRRRECLQCLTRFTTMERSVLLVTKRNGVTEEFSREKVIKGVKQACQGRDVSDDDLKLLAHEVEQSVRADYGSQVNAHDIGLAILPPLRRLDEVAYLRFASVYKSFSSSEDFEAEIALLRRQHQGNAPSSGS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PSBJ_STAPU
Sequence: MSNVGTSGRIPLWLVGTVAGILVLGLVGLFFYGSYVGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YXEG_BACSU
Sequence: MRNQKAERLVAAGLVLHIIQWIFILWAFLKVKHLFSDYTIYNPNVISGSMQSLSFIQMMRAMMYSGAIVNYVLFFALVLLIYGIVLHAILIVLEMAAYVMIRRNPSSSWGFFFIAAGVKLAILNITGIPFLAAGFLLMKQKKAENGVKAERKRKPRLRIRRQGRRLNRIRRKPSLPVEYQKEKTI
What are the official names of this protein?
Uncharacterized protein YxeG.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_METMP
Sequence: MAILKASEIRELSVEEMKGKIAELKRELMKEGVNKSTGGAPSNPGKISETKRTIARILTIMKEKEAQAENA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PYRE_CLOTE
Sequence: MENKNEFIIDILKECSALLEGHFLLSSGRHSDKYCQCAKLLQYPDKAEKVLKVVVDKIKDLDFDMVVGPAMGGIIVAYELGRQLKKPNIFTERQEGVMTLRRGFEIQKGKKVIITEDVVTTGKSSLEVAKLIEKLGGEVVAICSIVDRRDDNIELPYNLYSSVKIDVKSYEEKDCPLCKEGLEYIKPGSRNIK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRHO_STRP1
Sequence: MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y506_MYCPN
Sequence: MKFKYGAIFFSGFLGLSAILAACGTKGKFDQVDDGKIKLASSLTSKSASKALQAIVKKYNEVKKPGDYPIEITQIAGGYDGGRSDLQTRVNVKDTTNFYNLILNYPDLVSTLGRVGMELPFDNVKVDKLSPRFLDFNNRISAISKPGIYGIPVSLSTEVLSINGPVLHYILNNAKKKEGTLNQKMTSSSEGKNSSGTLTVATDTETSSLWKKIEDSAKANGKSDEKGKGKKKDNKSATFSLVQLKQTQEKTDDSQDTKNSDDQVKKSWGEYQEVDGVLKNFEFKASIFENWHDLLDFSTRVAKSFKKIHENSNKKGNDIQGILGVDSTPNSLFTSVFAAGGGDYNNFFYKIENGRADFSNFKNKGTSYQNLQKVFGDFKGLIDKNGIFVNKGGSYSSNFQKFHQLAYSISSTSGFFYSFAGKSAKRLNFGDSFIEYPRFTQEIKAPSKNGENGQTNEGNSTNGEQNLLGTFEVKDDSKPKEEVKSNKNSGKESSQNQGKKSNNNKTIYLYETKIPDGKTAGDNAILIKDKNVIEKLKSAAKEENKEQTAEATKAAITSNKAKSTKKESSKVIGYTTTDSVREDGKNIFAIDRVNGENYDRKIIVGAKAETLNQSSTLQSEEAIVLPAPGKYLNGDPKKVTITQGPNIIGIHANEKENAETQKFVDWFLNSPQTWEKQSRDKKGSSEKQTAAEFFAESASYILPLKEIFDKNDTKTEKGKNSKTQQRTNTYAEKALELFKQISQNQIVSYSDPSDFRSGKFRDAIGATFNAAVSSKADFNKFVQNFTATLGSDI
What are the official names of this protein?
Uncharacterized lipoprotein MPN_506.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CUTC_VIBCM
Sequence: MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDIRTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLGIERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQQTVHALAALNSVLH
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_PHOLL
Sequence: MSAPLTWHDVIGNEKEQPYFLDTLAYVAKERQAGKTIYPPQQDVFNAFRYTELADIKVVILGQDPYHGPNQAHGLSFSVQPGIPAPPSLVNMYKELASDIPDFQHPNHGCLISWAKQGVLLLNTVLTVERGNAHSHANLGWETFTDKVIAAINEHRSGVVFLLWGSHAQKKGYFIDANKHHVLKAPHPSPLSAHRGFFGCQHFSKANTLLEKQGIAPINWTPELPQ
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHI2_YERET
Sequence: MVNKYTYTSSKAMSDISDVIGEPLAAWDSQVGGRVFNVIFDGKVYTNTYWVERWQVPGIGSSDGNPHNAWKFVRAATADEINKIGNPTTADVKPTENIPSPILVEDKYTEETYSRPDVNFKEDGSQGNLSYTATRVCAPMYNHYVGDKTKPKLSAYITDWCQYDARLDGGGSKEEERGRGFDLATLMQNPATYDRLIFSFLGICGDIGNKSKKVQEVWDGWNAQAPSLGLPQIGKGHIVPLDPYGDLGTARNVGLPPESADTSIESGTFLPYYQQNRAAGLLGGLRELQKKAHAMGHKLDLAFSIGGWSLSSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIACSGVKAKLKKSNIDQLVANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGIPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSMGKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQDCGLLANAAREGLGYVADSNQETIDMGPLYNPGKEIYLKSISEIKSK
What is the function of this protein?
Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295).  The TC has an endochitinase activity (PubMed:21278295, PubMed:22158901) (Probable).  This subunit might aid infection by degradation of the larval peritrophic membrane (Probable).
What are the official names of this protein?
Chitinase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted when grown at 25 degrees Celsius or less, but not when grown at 30 or 37 degrees Celsius.
Protein: PYRB_BRUSU
Sequence: MTNQTVSPLFPHRHLLGIKGLSPLDILCLLDLADQEIAVSRQPEKKKSVLRGRTQINLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMQPDILVIRHASAGAAALLAQKVGCSVVNAGDGAHEHPTQALLDALTIRRAKGQIENLIVAICGDVLHSRVARSNILLLNALGARVRVVAPSTLLPAGMADMSVEVFNSMEEGLKDADVVMMLRLQRERMAGSFVPSVREYFHFYGLDREKLKFAKPDALVMHPGPMNRGVEIASDVADGPQSVIQQQVEMGVAVRMAVMEALLDPRRNPGNGEPA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL4_LEIXX
Sequence: MATSIDVVDLKGKKAGSIELPDSLFDVQTNIPLIHQVVTAQLAAARQGTHKTKNRGEVSGAGRKPFKQKGTGRARQGSIRAPQMTGGGIVHGPTPRDYSQRTPKKMIAAALLGALSDRARGSRIHAVQAFTAGEAPSTKAVVELLSGVATSKHVLVVLERDDELAFKSVRNIASVHALTYDQLNAYDVLVSDDIVFTQAALEGFIAAKSTSAATKKEEVNA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: YR096_MIMIV
Sequence: MSTVKKSSKKKSSKKSSSGNESSKKSSPKIVPKHTAKNLPKPIKNFEIDLDKCANCPGCLTYLSFIRQVENIIQQNSSRSTTTQLIVKLISNFVWKYRFTYEQIAVNLFKYKFKERGYLVKILVSLGFDPNNLKINGHKVLKILVYENDIPSIIALVENGANIDFGKAPSNILHICASRNYPVLLKYALSRNEIDINAVNIDGRSPLYLACLYLNKECIKILLDNGADVEVCTPDEKTCCLELIIFLGNIMHNNLEVYTEIYQRYGDKYSDNISELVGNIVDALKYIISAKNNMSRQEIYTIRNLCFNKPIVMNEKIVFDLFVFIMDKFPKIVYNKFTHLGHNAINTSIMFCNNSLIKYFVDKTDLDFQAINNNITNPIQMLVNHGYIDYVETILNRNPKIVSTKCRYNNNLLHYTLMPCYVYSNVPRIKSDKDIIELVKIFANNKKINQNHRNNSGYRPIEVAIRYCSIDVIKELLKYNTTIFAENRIKQQLFPVLNNNDIISFATQLGRFDVVTYLIQENVQFQLYQIDDIHTVPTALLIAIVYHRKNFIQFFLELPQITDCLNNDVTKEYVINFANMYSNYNVQITDTYNLNFIGNDKMSFTHRIDRMIHFYSVHYGYSKMVILSGLSTILSLLEKICLASKKCKNYRNLPNSKFLEATIFSNGPCDLTFRNEFSNLYTDINLLNYMNDSKFFDNIVEIIGDLIEYPILLDIFEYMFAVRDLPISSQPIIKFIESLGLINQSNKIIKINKIVNELLNKSEISIDLNDQDTHNYDDYVENDPEFDSDEFDTDEFSDEAIKDFFGLDNKNLLTDKTSSPIKPIKNNQKENFNKKIDKYRVENMLHKFCRGEKLPHYDIIYKCLMQTDYYQILDNKIVVHNNEIILAVIYKLKSSDSTNSQMSHKPSVKTNPSDWIKSYSTNICSPNKQDHYHMFPFVLDWILYKWSCVEFQTKDKIYPTEFNTHLYFYGELNTNGRMVKGCFEYFLNCHKSLYHRLFHEIDRVPPQIQRKIYNH
What are the official names of this protein?
Putative ankyrin repeat protein R96.
Protein: ATPA_MARMM
Sequence: MDIRAAEISAILKDQIKNYGAEAKVSDVGSVLSVGDGIARVYGLDEVKAGELVEFPGGIKGMALNLERDNVGCVIFGDDRGIKEGDTVKRLGSIVDTSVGKGLLGRVVDGLGEPIDGKGPLKGVAERRRVDVKAPGIIPRKSVHEPMATGIKAIDAMIPVGRGQRELIIGDRQTGKTAIALDTILNQKAINEGDDESAKLYCIYVAVGQKRSTVAQIVKTLEENGALDYTIIVAATASDPAPMQFLAPFTACAMAEYFRDNGMHALIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNEANGSGSMTALPIIETQANDVSAYIPTNVISITDGQIFLETDLFYQGIRPAVNVGLSVSRVGSAAQTKAMKQVAGKMKGELAQYREMAAFAQFGSDLDAATQKLLNRGQRLTELLKQPQFSPLSMEEQVCVIYAGTRGYLDKLPTSDVQRYEADLLRHLHGEHAALLASIRTEKKLTDDSESQLKAALAKFTEHFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ROLA_AGRRH
Sequence: MELAGLNVAGMAQTFGVLSLVCSKLVRRAKAKRKAKRVSPGERDHLAEPANLSTTPLAMTSQARPGRSTTRELLRRDPLSPDVKIQTYGINTHFETNLRD
What are the official names of this protein?
Protein RolA.
Protein: PGK_BORGP
Sequence: MSIKTVKDFNSFAGKRALVRCDFNVPLKEGNISDDTRIKAALPTIEYLKEKGARIVLISHLGRPEGKKNLKYSLKPVANKLSELLGQDVKMLSDCIGREIVNNTLQMKDGDVVLLENVRFYAEEEKNDKNFAKKLSENGDVFVNDAFGAAHRAHASTVGVSDYLPSVGGFLMEKEDKFLGEVLKNPERPFVSIIGGSKVSSKIAVLESLLSKSNVVVIGGGMAYTFLHSKGYSIGKSLLESEYIDIASSFLKKAKELDVKVILPLDHIVADDFNKNSTPEYIDSFDIPENKIGMDVGGKTLKEIEKVIKTAKTIIWNGPLGVFEFDSFSKGTAMVAEMVASCAGLTIVGGGDSVAAVNKFNLSDKITHVSTGGGASLEYLEGKILPGIKVLEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ECOK1
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODAM_HUMAN
Sequence: MKIIILLGFLGATLSAPLIPQRLMSASNSNELLLNLNNGQLLPLQLQGPLNSWIPPFSGILQQQQQAQIPGLSQFSLSALDQFAGLLPNQIPLTGEASFAQGAQAGQVDPLQLQTPPQTQPGPSHVMPYVFSFKMPQEQGQMFQYYPVYMVLPWEQPQQTVPRSPQQTRQQQYEEQIPFYAQFGYIPQLAEPAISGGQQQLAFDPQLGTAPEIAVMSTGEEIPYLQKEAINFRHDSAGVFMPSTSPKPSTTNVFTSAVDQTITPELPEEKDKTDSLREP
What is the function of this protein?
Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth.  May be incorporated in the enamel matrix at the end of mineralization process.  Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK.  Plays a role in attachment of the junctional epithelium to the tooth surface.
What are the official names of this protein?
Odontogenic ameloblast-associated protein, Apin.
What is the protein family that this protein belongs to?
Belongs to the ODAM family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Nucleus.
Protein: FENR_LIMF3
Sequence: MEERYDVTIIGGGPAGMFAAFYCGLHQLKAQLIEALPQLGGQPAALYPEKRVWDVAGKAGVTGQELADDLAAQIEVAPVDQFLGEKVTDVVKEDDGSFTIHSAKRTSTSKSIVIAMGNGAFSPRKLALPGAEELEGKQVRYFANHKEDFKDQRVAVLGGGDAAIDMALMLEDVAEQVYLVHRRDAFRALEHTVAQLEASTIEKLTPYLPKDLTVNADQSVTLNLKKMRADEERPLEVDKVLVNYGFTSNNAALKDWSLDLASERGQIKVDQTMKTSVPGVYAIGDGVVYEGKVALIATGFGEAPTAITNLAKELYPDKRMAIHSSSMGIG
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RENR_MOUSE
Sequence: MAVLVVLLFFLVAGALGNEFSILRSPGSVVFRNGNWPIPGDRIPDVAALSMGFSVKEDLSWPGLAVGNLFHRPRATIMVMVKGVDKLALPAGSVISYPLENAVPFSLDSVANSIHSLFSEETPVVLQLAPSEERVYMVGKANSVFEDLSVTLRQLRNRLFQENSLLNSLPLNSLSRNNEVDLLFLSELQVLHDISSLLSRHKHLAKDHSPDLYSLELAGLDELGKRYGEDSEQFRDASKILVDALQKFADDMYSLYGGNAVVELVTVKSFDTSLVRKSRTILEAKQENTQSPYNLAYKYNLEYSVVFNLVLWIMIGLALAVIITSYNIWNMDPGYDSIIYRMTNQKIRID
What is the function of this protein?
Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system (By similarity).  May mediate renin-dependent cellular responses by activating ERK1 and ERK2 (By similarity).  By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS) (By similarity).  Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission (PubMed:26376863, PubMed:29127204, PubMed:30985297).
What are the official names of this protein?
Renin receptor, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, Renin/prorenin receptor.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, autophagosome membrane; Single-pass type I membrane protein. Cell projection, dendritic spine membrane; Single-pass type I membrane protein. Cell projection, axon. Endosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Protein: RF1_POLNA
Sequence: MKPFLRHTLDRQLLRLHELDALLSASDVVSDLDRFRALTREHAEASVVAEQYNRLTAREADLASAESMLAEAKNDPDMAEMAEEEINAAKTDIAQLDEALQLMLIPKDPDDRRAAFIEIRAGTGGDESALFAGDLFRLYTRFAERKRWQVEIISESPSELGGYKEVVLRIDGPTDAMGVGVYGKLRFESGGHRVQRVPATETQGRIHTSACTVAVLPEPDETVAIQINPADLRIDTYRASGAGGQHINKTDSAVRITHLPTGIVAECQEGRSQHGNKAQAMKVLTARIHEKERSAQAAKDAAMRKGLIGSGDRSDRIRTYNFPQGRLTDHRINLTLYKLLTIMEGDLDDVVTALQVARGAEQLNELETANNGG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANR_ECOLU
Sequence: MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQSTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: LRRT3_MACFA
Sequence: MGFNVIRLLSGSAVALVIAPTVLLTMLSSAERGCPKGCRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAVKNYSICGKSTTERFDLARALPKPTFKPKLPRPKHESKPPLPPTVGATEPGPETDADAEHISFHKIIAGSVALFLSVLVILLVIYVSWKRYPASMKQLQQRSLMRRHRKKKRQSLKQMTPSTQEFYVDYKPTNTETSEMLLNGTGPCTYNKSGSRECEIPLSMNVSTFLAYDQPTISYCGVHHELLSHKSFETNAQEDTMETHLETELDLSTITTAGRISDHKQQLA
What is the function of this protein?
May play a role in the development and maintenance of the vertebrate nervous system.  Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity).
What are the official names of this protein?
Leucine-rich repeat transmembrane neuronal protein 3.
What is the protein family that this protein belongs to?
Belongs to the LRRTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic cell membrane; Single-pass type I membrane protein.
Protein: METJ_VIBA3
Sequence: MADWNGEYISPYAEHGKKSEQVKKITVSIPLKVLKVLTDERTRRQINNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPTEVKKLMTEMGIEFEAFDEE
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_VIBCH
Sequence: MIDGDGYRLNVGIVICNNHGQVFWAKRYGQHSWQFPQGGIDDGESPEQAMFRELYEEVGLTKKDVKVIATSRHWLRYKLPKRLVRWDSQPVCIGQKQKWFLLRLECDESKINMQRGSSPEFDGWRWVSYWYPVRQVVSFKRDVYRRAMKEFASLAMPFKERKVKGKRNTHRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: GATA_SCHPO
Sequence: MSNKYNNLLKEVAAKYASIILNDAKIKSLTSINSAEYLYDSFVEISKLPLEKKLPLKWKLITVKENICTKTNLTTAASNMLKDYNSPFDASIVESLKKAGGIILGKTNMDEFAMGVKSENNLFGRTVNPVVKDSNYDVGGSSGGAAAAIAADICYASVGSDTGGSIRLPAAYVGCVGFKPSFGRISRYGMLAFANSFDTVGIAANNVKGVTKVFNVLDHPDINDSTCLTKEARYFVKEQHKKLSRKPIKIGIPIDWNVSETHPNVLDKWNEFISLLKSNGYLVQEIQLPISLYANSVYSTMAYAEATSNLAKYNTIAFGNCLDEKFEEEIISSTARSFFLGDEVKKRLLLGAYSLARMNSSDLFSKARYVRRAIQLEFNKNFFLPSFSVDDPRGDIDFIVTPSFFNSSQPIETPSSYSHLSDTMLVPANMAGIPSVSIPFGTLNNGLPMGIQIMAQYLNDEDLLSFAGQFA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL361_LEIXX
Sequence: MKVNPSVKKICDKCKVIRRNGRVMVICENPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TIP12_ARATH
Sequence: MPTRNIAIGGVQEEVYHPNALRAALAEFISTLIFVFAGSGSGIAFNKITDNGATTPSGLVAAALAHAFGLFVAVSVGANISGGHVNPAVTFGVLLGGNITLLRGILYWIAQLLGSVAACFLLSFATGGEPIPAFGLSAGVGSLNALVFEIVMTFGLVYTVYATAVDPKNGSLGTIAPIAIGFIVGANILAGGAFSGASMNPAVAFGPAVVSWTWTNHWVYWAGPLIGGGLAGIIYDFVFIDENAHEQLPTTDY
What is the function of this protein?
Water channel required to facilitate the transport of water across cell membrane.  May be involved in the osmoregulation in plants under high osmotic stress such as under a high salt condition.  Transports urea in yeast cells in a pH-independent manner.  Transports H(2)O(2) in yeast cells.
What are the official names of this protein?
Aquaporin TIP1-2, Gamma-tonoplast intrinsic protein 2, Gamma-TIP2, Salt stress-induced tonoplast intrinsic protein, Tonoplast intrinsic protein 1-2, AtTIP1;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: SURE_SHESM
Sequence: MIRILVSNDDGVNAPGIKALTEALAEIATVMTVAPDRNCSGASNSLTLTNPLRINRLDNGYISVHGTPTDCVHLAIRELCDGEPDMVVSGINAGANMGDDTLYSGTVAAAMEGRFLGFPAVAISLNGKALKHYHSAAVYARRIVQGLLAHPIASDQILNINVPDLPLDEIKGIRVTRLGARHKAEGIVRTQDPAGREIFWLGPPGVEQDASEGTDFHAIAHGYVSITPLTVDLTAYRQLSVLQDWVDKI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.