PharMolix/UniProtQA huggingface dataset:
Protein: PSA3_SCHPO
Sequence: MSRSYDSRTTIFSPEGRLYQVEYALEAINHAGVALGIVAKDGIVLAAEKKVTSKLLEQEESAEKLYHIGDNMLCAVAGLTADANILINYARRVGQQYLQTFNEEMPCEQLVRRVCDLKQGYTQYGGLRPFGVSFLYAGWDHIRGYQLFQSNPSGNYGSWQANSIGGNSTSVQSLMRQEYKDDINLDEASAMAVKFLSKTLDSNSLTHEKIEFATITKDTTKNKMVCKIWKSDEINEVLNKYQETQRQS
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit alpha type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DJC22_MOUSE
Sequence: MAKGLLMTYVLWALGGPVGLHHLYLGRDSHALLWMLTLGGGGLGWLWEFWKLPSFVAQANRVQSWKQRPEEERPPLSLLRFASQIVVGVYFGLVALVSLSSMDNFYIVGLPLAVGLGVLLVAAVGNQTSDFKNTLGAAFLTSPVFYGRPIAILPISLAASITAQKHRRYKASAGSETLSVRLYRVGLAYLAFTGPLAYSTMYNTAATINYVAETLGSFLSWFSFFPLLGRLVESVLLLPCRIWWLLVGGPGFNSSRFQEWEKLYEFVDSFQDEKLQLAHQVLGVPEGATNEEIHRSYRDLVKVWHPDHNRHQTEEAQRHFLEIQAAYEVLSQPKKPRAS
What is the function of this protein?
May function as a co-chaperone.
What are the official names of this protein?
DnaJ homolog subfamily C member 22.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1274_HISS2
Sequence: MLCAIYKTKRKEGMYLYIEKRGHFDSVPSSLLESFGKPIFVMLFNLAGQKSLINANNEDVQQQIKQNGFYLQMPKQQENLLEQERQYLKHNK
What are the official names of this protein?
YcgL domain-containing protein HSM_1274.
Protein: PA_INBAC
Sequence: MDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISDMNFLDEEGKTYTALEGQGKEQNLRPQYEVIEGMPRNIAWMVQRSLAQEHGIETPRYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSNESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDIEKGIDFKLGQTISKLRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLKWEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECLEKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEETSNELQKTNYAKWATGDGLTYQKIMKEVAIDDETMYQEEPKIPNKCRVAAWVQTEMNLLSTLTSKRALDLPEIGPDVAPMEHVGSERRKYFVNEINYCKASTVMMKYVLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLHGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDRVNSPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLGFEKEGSKVLESIDEIMDE
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: Y3621_RHOP2
Sequence: MTVFAASQQSAAGAGMLPSHQARLACRAGQADTTAGVAPGYVQGNLAILPEKFAAAFHRFCQLNPKPCPIIGMSDVGNPMIPALGLDLDIRTDLPRYRVWRDGEVIEEPTDIMAHWRDDLVAFVIGCSFSFEEALLADDIAIRHIDCKVRVPMYRTNIPCAPAGPFAGPMVVSMRPMKPKDAIRAVQITSRFPSVHGAPVHIGLPQSIGIADIAKPDYGDPVPIADDELPVFWACGVTPQAVIAAAKVPFAITHAPGLMLVTDLKNKHLAVL
What are the official names of this protein?
Putative hydro-lyase RPB_3621.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: RBL2_RHORT
Sequence: MDQSSRYVNLALKEEDLIAGGEHVLCAYIMKPKAGYGYVATAAHFAAESSTGTNVEVCTTDDFTRGVDALVYEVDEARELTKIAYPVALFDRNITDGKAMIASFLTLTMGNNQGMGDVEYAKMHDFYVPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKPKLGLRPKPFAEACHAFWLGGDFIKNDEPQGNQPFAPLRDTIALVADAMRRAQDETGEAKLFSANITADDPFEIIARGEYVLETFGENASHVALLVDGYVAGAAAITTARRRFPDNFLHYHRAGHGAVTSPQSKRGYTAFVHCKMARLQGASGIHTGTMGFGKMEGESSDRAIAYMLTQDEAQGPFYRQSWGGMKACTPIISGGMNALRMPGFFENLGNANVILTAGGGAFGHIDGPVAGARSLRQAWQAWRDGVPVLDYAREHKELARAFESFPGDADQIYPGWRKALGVEDTRSALPA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: NADE_STRT1
Sequence: MTLQETIIAQLGVKPSINPKEEIRKSVDFLKAYMIKHPFLKTYVLGISGGQDSTLAGRLAQLAVEELRAETEKDYQFIAIRLPYGVQADEDDAQRALAFIKPDVSLTINIKEAVDGQVAELAKAGVNVSDFNKGNIKARQRMITQYAVAGENSGAVIGTDHAAENLTGFFTKFGDGGADILPLFRLNKRQGAALLAELGADKALYEKVPTADLEEDKPGIADEVALGVTYHEIDDYLEGKEVSAKAQETIETWWRKGQHKRHLPITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: SYFB_PSEF5
Sequence: MKFSEQWLRGWVSPQVSRDELVARLSMAGLEVDSVTPAAGDFSGVVVGEVLSTEQHPDADKLRVCQVSNGSETFQVVCGAPNVRPGLKVPFAMIGAQLPGDFKIKKAKLRGVESNGMLCSQAELQIGEGNDGLMELPVDAPVGEDVRTYLSLDDASIEVDLTPNRGDCLSLAGMAREVGALYAAKVQRPEVPAIPAAHDEVRPVEVLAPAACPRYLGRVVRNVDLSKPTPLWMVERLRRADVRSIDAAVDITNYVMLELGQPLHAFDLAEINGGIRVRMAEEGEKLVLLDGQEVTLRSDTLVIADHTRALAIAGVMGGEHSGVTANTRDVFLESAFFDQIAVAGKARSYGLHTDASHRYERGVDWQLAREAMERATGLLLEITGGDAGPIIETLSEQHLPSVAPVTLRAERITQMLGMEIDGLEVERLLTALGLTVTADGAGQWRVEVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPQAKAEAEGDLPALRRLLVARGYQEAITYSFIDPKLFELFNPGVEPLLLANPISADMAVMRSSLWPGLVKALQHNLNRQQDRVRMFESGLRFVGQLEGLKQQPMLAGVVCGSRLPEGWAQGRDGVDFFDVKADVEAVLGFAGALDAFTFVPGKHPALHPGQTARIERDGREVGFLGAIHPELAKNLGLDRPVYVFELVLSEVAQGRLPKFHELSRFPEVRRDLALLADRDVAASSVLDVIRENAGEWLTDLRLFDVYQGKGIDPHRKSLAVGLTWQHPSRTLNDDEVNSTTQNILTSLEQRLNATLRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCA10_XENLA
Sequence: MEGCTKDGAAVQSSGASTAGSIFWWLKDRSLGRGICVDPARDNFRTMTSLYSSIHPADSVNLSTRTHGAVFNLEYSPDGSVLTLACEQTEVLLFDPLSSKHIKTLSEAHEDCVNNIRFLDNRMFATCSDDTTIALWDLRKLNSKACTLHGHTSWVKNIEYDKNTRLLVTSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHELDLTKSLEVGSYPILRARRTASTSDMTSTSSETRPSSSPCHNSDSGPLFEKHMSRSSQREGTSPRNSLEVLTPEVPGERDRGNCITSLQLHPKGWATLLRCSSNTDDQEWTCVYEFQEGTPVRQVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRMIASPHGYGIRLLGFDSQCKELVDCLPKEAGTLQEIRSLYSHKDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 10, WD repeat-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF10 family.
Protein: FACR1_DROME
Sequence: MSHAVANKTETEAAPNSSLKQSAAPQPANSHDAKLLNGTLARTNGLTHAASVATSSSGSYGSSSAAGSNAGSGGPTSSASLSIAAGVASSTALPLPPSSNGLQMPYERFRADDTSYVPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFESLRQEKPKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLGTKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPEDILDQLTPRLIGKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWRTATRKSNNLLIYNCCTGQRNPIIWSEFVKHAMTSVRKHPLEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMGKKPFVVNVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGFREFLFKQRPESLPASRKRMLRLYYLHQLTKLVAVLLTWRFLMSRSKRLNDLWSSFLENALRMARLIPFL
What is the function of this protein?
Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols.
What are the official names of this protein?
Putative fatty acyl-CoA reductase CG5065.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: METJ_ERWT9
Sequence: MAEWNGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDVDLRKERSDEIPEEAKAIMRAMGVDPDTWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4037_BURCJ
Sequence: MTPSEFRQSVRRGAFRGPTAGHCGPFAQANLAILPDAYAHDFLRFCQANPKACPLLGVGEPGAFRIAALGEDLDIRTDVPSYNVYRDGRLTERVESLEALWQDDFVVFAIGCSFSFEDMLAREGIGLRHVEEGRNVPMYRTSIANRRAGIFGGQLVVSMRPLRGADAIRAVQITSRFPGVHGAPIHIGHPRELGIDDLNAPEFGDAVTIRDGELPVFWACGVTPQTALMDAKLPIAIAHTPGHMLMTDITNASLAVF
What are the official names of this protein?
Putative hydro-lyase BceJ2315_40370.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: LPXB2_LEGPH
Sequence: MTMKRPTRIAMVAGELSGDLLGAGVIRELKQHLTNVEFMGVGGPQMLKEGFHSLIDISELSVMGISDVLRRYPQLYLIRERLLREWTINPPDVFIGIDYPDFNLSVEARLKKQHIKTIHLVSPKVWAWRQKRVHLIKKAVDLVLTLFPFEEAFYRQHGVSAQFIGHPLADLIEINPSCSTLRKKYNYHSDDTILAVLPGSRVGEIKYMGPLFLEVMQRIAVERPHVHFIVPIACQDLYPVFFKQLHAEYGHLKIQIIQGNAREAMAISDVVLTKSGTATLEAMLLKRPMVVAFKWGILTHAIIAPQVKVPYIALPNLLAGKKLIPEFVQEKANVDSITESVLNLLDSSNQNELIKQFTDIHCTLRQNANEKAALSILRILGTSLT
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase 2.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RHLB_SALG2
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_ALIF1
Sequence: MSKIVKVLGREIIDSRGNPTVEAEVHLESGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAVAAVNGPIAEALVGKDAKNQAEIDQIMIDLDGTDNKANFGANAILAVSLANAKAAAAAKSMPLYAHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANQFPIVSIEDGLDESDWTGFKHQTELLGDKLQLVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PYRC_LACDA
Sequence: MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRMAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQAALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: U184_BRAFL
Sequence: MANVNGYVDLLEGIPDETKEEMVELNNTLDKLDSCLDALEEQNDSLNAKLRDLLQSSQQARQELQAERQSLETEQNTEPSTKSDQEQKKQ
What are the official names of this protein?
UPF0184 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0184 (EST00098) family.
Protein: RS14Z_MYCCT
Sequence: MAKKSLKVKQAKHQKFNVRNYTRCNHCGRPHAVLKKFGICRLCFRKFAYEGQIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: VORC_METTH
Sequence: MKKAYPVINSVECKACERCIIACPRKVLQMSSKINERGYHYVEYRGEGCNGCGNCYYTCPEINAIEVHIERCEDGNTDG
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorC, VOR, 2-oxoisovalerate ferredoxin reductase subunit gamma, 2-oxoisovalerate oxidoreductase gamma chain.
Protein: YDHI_ECO57
Sequence: MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLLRGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW
What are the official names of this protein?
Uncharacterized protein YdhI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS15_SYMTH
Sequence: MPLSQEEKQRIINEFKTHETDTGSPEVQIALLTHRINELTEHLRVHKKDHHSRRGLLKMVGQRRALLVYLNKISPERYAKLIDRLNIRTVIR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SYM_PORG3
Sequence: MDRQFKRTLITTALPYANGPVHIGHLAGVYVPADIYARYLRLRGRDCLLIGGSDEHGVPIALKAKAEGCTPQEVVDRYHELIKRSFEGLGISFDIYSRTTSDIHRRTASEFFKTLYEKGEFVEQTSEQYYDEEAKQFLADRYIIGTCPHCSNDRAYGDQCEACGTSLNATDLIDPRSTISGSAPVLRETKHWYLPLDKHEPFLKEWILDGHKEWKSNVYGQCKSWLDMGLQPRAVSRDLDWGIPVPVEGAEGKVLYVWFDAPIGYISNTKELCPDSWETWWKSEDTRLVHFIGKDNIVFHCIVFPAMLRAEGSFILPDNVPANEFLNLEGDKISTSRNWAVWLHEYLEEFPGKQDVLRYVLTANAPETKDNDFTWRDFQARNNNELVAIFGNFVNRALVLTHKYFDGAVPPKGELTDYDSRTIEEFAAVKQALEHQLDTFHFREALKEAMNLARIGNKYLADTEPWKLAKTDMNRVATILNLSLQITANLAIAFEPFLPFSSAKLMSMLSTDCPFGWDRLGSTDLLPEGHVLGNPELLFEKLEDSVIDAQIQKLQDTKLANEKAAHQAAPIAEDIAFEDFLKLDIRVGTVLECEKVPKADKLLRFRIDDGLGGRTIVSGIAKHYAPEELVGKQVCFIANLPPRKLKGIESEGMILSAEDADGSLRVIMPAAEVAPGSQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_SODGM
Sequence: MMRSLNRCSKHRAAWLLLALTTFSLELVALYFQHVMLLKPCVLCVYQRCALYGVVAAGLVGAIAPATPLRFSGLAIWLYSAWEGLQLAMKHTDIQLHPSPFVTCDFFVSFPAWLPLDKWLPSVFSASGDCAVRQWHFLSLEMPQWMIVIFGAYLAVAVLILLAQFFPPRKRDLFSR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RABL_MIMIV
Sequence: MNSYIKEKMENNGYKIILIGSSGVGKSSIVHQFLFNRKISNVSPTIGAAFASKQVIAKNGKTLKLNIWDTAGQERFRSITKMYYTNSLGCLVVFDVTDRESFDDVYYWINDLRINCHTTYYILVVANKIDIDKNNWRVSENEIKKFCRDNDCDYVFASSFESDTVNNLFGKMIDKMSEIKINPDSRRNDIIYLSDKSSGIDDFIDKISQNCCYIS
What is the function of this protein?
May be involved in protein transport.
What are the official names of this protein?
Probable Rab-related GTPase.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GSHB_DICDI
Sequence: MEEKLNDLKEQGIDWAFANGLIMIKKPTEEEAKNNVVNVTHVPFSLYPSKMNKKLFNEACKLAEDYNLLVHNISKDYDFLQNTLKDVFDDFTQMLLNIQRKVVKEGIKQKISLGIFRSDYMFHNKIEGEEERIYQVELNTISSSLAVVSNRVFNLHKYLIGRNDLNDNGYDLLNHPTNQSDKEISDSIALAHKLYNKEKSSVVLMIIQEGERNIYDQKGLEFQLWSNHSIKLIRRTMKEINQCAKLDEENGSVLIVDGMEISVAYYRAGYTPNDYTSSGGDEWKARLLIERSLAIKCPTIAHHLVGVKKIQQVLAQPGVLEKFINNDKESLQRVKRSFTGLYSLSKEDIDMSVVKEAIESPQNYVMKPQREGGGNNIYNDQVAIALKSMSSEELSSYILMDKIMSKSFKTHVVRDRQLLEIEGLYELGIYSVFISNGDDDIVLNKQAGILLRTKTANSDEVGVAAGFGLLDSPILE
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
Protein: ARMX5_MOUSE
Sequence: MIGSKTKRKAREESGASSKPGTNSPANAKGKAKNQTTKAVKAEPKEEWGNQAEARDEAVARTQPAISTEPKTVTWKVKKKKDKTNARVMAQAKTELPAGPALVPHTKSDALPTSVVITVTKSEVKIDTGIEASLKGAAKATDKRSIKQKPEIKKEVCVKSRAGDKAKEVCVKSSAGDKAKEVCVKSRAGDKAKEVCVKSRAGDKASIVINTTDEDEDYVCSWFWTGEEPSVGSWFWPKEENPLQVYQPPPKVEEEPEPPDTFDYALKKKAAAWLRGRFIVLVPIEEPQPSLPPDGNWTLVATLIETPLGIRPLTKIPPYGGPYFQTLADLKNQIREKEKYGPNPNTCRCKSRTFSLEPVDFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKKYPRTLNINANPDAPEEVKETEAHVNKVCRDILCCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVLLCLSKNQANTRELISAEVMSSLVALFHKNESKANILHIIEIFENINFQFKKRAKLFTKEMFTKSELISIFREAKEFDQKLQDLTDHSDPDVRDKVIRLILKL
What are the official names of this protein?
Armadillo repeat-containing X-linked protein 5.
What is the protein family that this protein belongs to?
Belongs to the eutherian X-chromosome-specific Armcx family.
Protein: CASP2_TRIPD
Sequence: MDSKSGRSESAINIPESNSTKHKSTVVHTATKVAAVAPRGGGWRRGVSIFDFILRICALAAALAATATMGTTDQTLPFFTQFFQFQASYDDLPAFTFFVVANGIASGYLVLSLPFSIATIVRPHAAAIKLLLIIFDTVMVAFTAAAAAAAAAIVYLAHNGNSKTNWFAICQQFNDFCQRVSGAVVASFVAAVILIFLVVLSAVAIRKH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, TpCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: KCY_STRMK
Sequence: MNPLAPVLTIDGPSGAGKGTISRIIARRMGWHYLDSGALYRAVGVAASWADIDTSDASALVRCTFDTHVQFVEQGESMRVMVNGTDATDELRLETTGALASAIAAIPEVRAALKERQRAFRELPGLVADGRDMGTVIFKDAPYKVFLTASAEERAERRHKQLKDKGVSVNFDDLLREIMARDARDAQRTVAPLKPADDAVLIDTTGIGIDDVVARVMDLLPVPAA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRZ1_CANAL
Sequence: MSNNPHPQDDGSQLYDNFEISPPSIVIRKADTDQSLNKIMLNQESQDINNYYTENVKNDNNPNNSYQDYTFSGNSSNQQHQQQQQQHLYEDLPTQFHYSNNSFFEPPPAPTVELTDDPLPNFNYPPSNIYINDNASDISLNTKDLPQFTTNEFLSPTSQLSTPFSPGHYSQSSQDFLQVNHTNGSGNNNNNNNNNNLLNPRSPSQYSSHSLYSDNSSQPASPFLDAASHVSNNSFIPPVIPTALSDVGSQNLDPSHNLGLSANQHFDSVNEFLSTGEIQLGQSVSSTNLPSMEEDSIKWGGGNGQEAYTSLAMMEQRASADNSGMRLATHQFSETQIKQEDQQTNMNHQYTFSNPQMNFDFDITVTPPPQQLEVKPFGNDKDMNNSSGTTNNNNNNSQFDIVSTAATNNSNQLLTENNLSNYNQLQRTEQGNDNDSLQIHRDATGIIISINQAPEEIAAKTPSLFSNSSANSSIHNSPRSDIDNKSGQYYNNGGDGNSLVPNSQLLPSSPNSNNDNYGGGGSSNDENNLLNPEEFQSVKRGRRKSHASRTSTNPNSLSPRSRSRSRSSAKSSNDAVISDNDESDDVLQSREKMLELALPSSSSKRTQKHPSLYACHLCDKRFTRPYNLKSHIRTHTQEKPFICSKCGKSFARSHDKKRHELLHQGIKNFKCEGYLQDGTRWGCGKSFARADALRRHFQTEAGKQCVKRLLLEEQANSSGKPLATSSGVEIT
What is the function of this protein?
Transcription factor involved in the regulation of calcium ion homeostasis and required for the maintenance of membrane integrity.  Binds to the calcineurin-dependent response element.  Plays a role in azole tolerance.
What are the official names of this protein?
Transcriptional regulator CRZ1, Calcineurin-responsive zinc finger protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the nucleus in a calcium- and calcineurin-dependent manner.
Protein: SH24B_HUMAN
Sequence: MLQQILHDMYIDPELLAELSDVQKHILFYKMREEQLRRWKERETWEALAQDEGLRPPKTKRASDKHIQWLLGADGEVWVWIMGEGPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQLHCQASEKEEREWEEQLRRSKAADEERSRRAQRARDEYRHHSLRAIQKGTVAGLSSMFRELGQSHEQEARLYHHLPDPGLPQPLALPVRTWERPLRPVSRDVIVRWFKEEQLPRRAGFERNTKFIAPWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGFKHFLVDASGDFYSFLGVDPNRHATLTDLVDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE
What are the official names of this protein?
SH2 domain-containing protein 4B.
Protein: DNAE2_PSEPK
Sequence: MAAGLVRMNTPGYAELHCLSNFSFQRGASSADELFRRAREQGYQALAITDECTLAGIVRAWQAAKVHQLRLIVGSEVQLCDGPKLVLLVENLTGYQNLCALITRARRRAEKGAYQLFRDDLLLHHQGLLALWVAADSGDTATGAWLRSVFAERLWLAVHLHRGSDDAVRLQRLRALAADVGIRAVACGDVHMHVRGRRALQDCMTAIRQHCQVSEAGRFLFANGERHLRSQAQLAELYPLDLLAETLVIARRCQFDLSELNYQYPRELVPEGHTPASWLRELCEQGMPLRWPDGPSGKVRDVLAKELGLIEELGYESYFLTVHDIVAFARSQRILCQGRGSAANSVVCFVLGITELDPMKHHLLFERFLSRERNEPPDIDVDFEHDRREEVIQYVFRRYGRHRAALTAVVNTYHAAGAVRDVARALGLPADQVDALAKCCGRWSDRIPDDQRLAEAGFEAGSPSLRRVLVLAGELIGFPRHLSQHPGGFVISQQPLDQLVPVENAAMPERTVIQWDKDDLDMVGLLKVDVLALGMLSALRRCFDQLQHHRGRHLTLATIPSEDPATYAMISRAETMGVFQIESRAQMAMLPRLRPQKFYDLVIEVAIVRPGPIQGDMVHPYLRRRLKQEPVTYPSPQLKEVFERTLGVPLFQEQVMELAMVAADYTPGEADQLRRSMAAWKRHGGLEPHRERLVQGMLRNGYTLAFAERIFEQIKGFGSYGFPESHAASFALLCYASSWLKCHEPAIFTCALVNSWPMGFYSPDQLLQEARRQGIEVRPVDVCHSDWDCTLEPDAEGTLAIRMGLRLVRGLAEADAKRVQQARSQRPWRNVEDLCLRAGLDARARARLADGGALRALASDRHQARWQVAAVQPQLPLFADVQALPEEPVQLPVPTVGEDLMADYQTLGTTLGPHPLALLRARLRALGCRSSSELQGVEHGDNIAVAGLVVGRQRPQTASGVTFVTLEDEHGMVNVVVWRALAERQRRALVGSQLLKVSGRLEQENGVRHLIARRLEDVSPLLQGLDVRSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.