PharMolix/UniProtQA huggingface dataset:
Protein: ATG4_PODAS
Sequence: MKSTRSGSNNWQSAVSGTSPKIATAMEAAISAGAEVSRVGRRILQRIWDPEPTNDRSNNEPVWCLGCSYLLDTKEYGTPPTLTTSTPPADATLTAIVPEPGAGVESEPRRATEKAGVPVNTSNAKAVAPIPVAASGQHQLQVPETPPLSVASSFDSALAYEEPGQDGGWPPAFLDDFESRIWMTYRTGFEVIPRSTDPKAAAALSFTMRFKTSFGDQTGFSSDTGWGCMIRSGQSLLANAMLISRAGRAWRRTTNPDIEREIVCLFADDPRAPYSIQNFVNHGAAACGKYPGEWFGPSATARCIHSLRVYLTRDLPEVYEDNFMSTANPDGNHFHPTLILVSTRLGIDKINPIYHEALISTLQLPQAIGIAGGRPSSSHYFIGAQGQWLFYLDPHHPRPALPYRENPNDYTIEELDSCHTRRLRHLHVEDMDPSMLIGFLIKDEDDWDLWKSSVKHVQGKAIINVSPHDPEHGMGFGRAGAIDEVETLSDEDDTDTVLDL
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: ADD_SERP5
Sequence: MIDSRLPLTDIHRHLDGNIRAQTILDLGRQFNLALPADELEALRPHVQITHAEPDLVSFLQKLDWGVAVLGDLEACRRVAYENVEDAANAGLHYAELRFSPYYMAMKHQLPVTGVVEAVIDGIRSGSRDLGIDVRLIGIMSRTFGEAACLQELEGLLAHRDGITALDLAGDELGFPGGLFLNHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDFLAEHGIGIESCLTSNIQTSTVASLAQHPLAKFLRHGVMASINTDDPAVQGIEIEHEYLVAAPQAGLTPAEIRTAQENGLKMAFLSEQEKQTLRDKVRG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: FTSB_ERWT9
Sequence: MGKLTLLLLVLLGWLQYSLWLGKNGIHDYTRVDEDVASQQGNNAKLKARNDRLFAEIDDLNGGSEAIEERARNELGMIKPGETFYRLVPDQNRRNAQQGRPASQ
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CADH6_HUMAN
Sequence: MRTYRYFLLLFWVGQPYPTLSTPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEAIEDNKLRRDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADMYGGVDSDKDS
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-6, Kidney cadherin, K-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TP8L2_CALJA
Sequence: MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPQAQRVIKDLIKVAVKVAVLHRNGSFGPSELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLIECRDVLLELVEHHLTPKSHGRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKMLDEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits JUN/AP1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: TGB1_FXMV
Sequence: MDSEIVERLTKLGFVKTSHTHIAGEPLVIHAVAGAGKTTLLRSLLELPGVEVFTGGEHDPPNLSGKYIRCAAPPVAGAYNILDEYPAYPNWRSQPWNVLIADNLQYKEPTARAHYTCNRTHRLGQLTVDALRRVGFDITFAGTQTEDYGFQEGHLYTSQFYGQVISLDTQAHKIAVRHGLAPLSALETRGLEFDETTVITTKTSLEEVKDRHMVYVALTRHRRTCHLYTAHFAPSA
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Increases plasmodesma size exclusion limit.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Movement and silencing protein TGBp1, 25 kDa protein, Silencing suppressor P25, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp1 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: B3A2_PONAB
Sequence: MSSAPRRPAKGADSFCTPEPESLGPGTPGFPEQEEDELHRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGPGRKPRRRPGASPTGETPTIEEGEEDEDEASEAEGARALTQPSPVSTPSSVQFFLQEDDSADRKAERTSPSSPAPLPHQEATPRASKGAQAGTQVEEAEAVAVASGTAGGDDGGASGRPLPKAQPGHRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQSGREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDPHVTEPLIGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVLLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAVARPTLGPGNRSLAGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMPV
What is the function of this protein?
Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (By similarity).  Plays an important role in osteoclast differentiation and function (By similarity).  Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity).  Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell response (By similarity).
What are the official names of this protein?
Anion exchange protein 2, AE 2, Anion exchanger 2, Solute carrier family 4 member 2.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CT54_CONLT
Sequence: MRCLPVFIILLLLIPSAPSVDAQPTTKDDVPLASLHDNAKRALQMFWNKRDCCPAKLLCCNP
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This toxin inhibits tetrodotoxin(TTX)-sensitive sodium channels, but does not affect TTX-resistant sodium channels.  Reduces the amplitude of currents without changing the activation and inactivation kinetics of currents.
What are the official names of this protein?
Mu-conotoxin Lt5d, Lt5.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
Protein: VGLN_ARV
Sequence: MDFLRQCTLIQVMILAITIRLTHGGWTNFPESCVQLQPENAYDEMCDDSSLTNSNSIEYHNKLKSTKKFCILNQIKSVKTNLYRCYNISITSVCNSELSSQNLHQDYEVNPISRRDCLKHIIKNWNDENLERSLIQKSEDIYRTRCNFLKNTETKIEDYIIYQEKTESSVINADGLDSMIETKLIELESNKKLDNTVKTCISWEQGGDSRFNTLNLIALDLNLCLAKNSYKLEKCLLCYFFIGQDKWYRGEDGFMISIELSELDTKSIPKCEILWYRLYPGNLLTINQDYLAKKVQERNRGCNAVKSILRSGKAPPLENMIKYTIPLQAGYGIGFREKIEKTVYSAPLRGNLVERRNYDFFRCHYFPSKIKIVENKTHTPPINLCVYHFGKGSCHYPDNKYFISMNPVSFEENQHYPKSGQSFDYQSGLNGIRKKIKNQEYYIPDSFLMTLIYSSHTKSILEKTNITEVFRNDSNYENHTLQDYLGLFNKEDEGMRPERDLINLPNITSETEDDDTSDLNLELNKNLINKTSSGFSNDNSNVINIPSKEYNKTDIKTVGKINKTSIIINHEEKDYWHEEYNMWGLSGLSFLLLLALFYNKIKRKIKRKS
What are the official names of this protein?
Non-structural glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ephemerovirus glycoprotein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYSC_RIPO1
Sequence: MKQQGVTIWLTGLSGAGKTTITHALEQKLREAGYALEVLDGDIVRTNLTKGLGFSKEDRDTNIRRIGFVANLLTRNGVIVLVSAISPYRDIRDEVRGTIGNFVEVFVNAPLNVCEERDVKGLYKKARAGEIKSFTGIDDPYEPPLNPEIECRTDLETLEESVTKIWQKLEELGYLAKPVAI
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: CENPT_MACFA
Sequence: MADHNPDGDPTPRTLLRRVLDTADPRTPRRPRSARAGAQRALLETASSRRLSGQTKTIAKGRSRGARSIGRSAHVQARGHLEEQTPRTLLKNILLTAPESSILMPESVVKPVPAPQVVQPSRRESSRGSLELQLPELEPSTTLAPGLLAPGRRKQRLRLSMFQQGVDQGLPLSQEPQGNADASSLTSSLNLTFATPLQPQSVQRPGLARRPPARRAVDVGAFLRDLRDTSLAPPNIVLEDTQPFSQPTVGSPNVYHSLPCTPHTGAEDAEQAAGRRTQSSGPGLQNNSPGKPAQFLAGEAEEVDAFALGFLSTSSGVSGEDEVEPLHNGVEEAEKKMKEEGVSVSEMEATGAQGPSRAEEPEGHTQVTEAEGSQGTAEAEGPGASSGDEDASSRAASPELASSTPESLQARRHHQFPEPAPPPGAAVLSSEPAEPLLVRCPPRSRTTGPRPRQDPHKAGLSHYVKLFSFFAKMPMERKALEMVEKCLDKYFQHLCDDLEVFAAHAGRKTVKPEDLELLMRRQGLVTDQVSLHVLVERHLPLEYRQLLIPCAYSGNSVFPAQ
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.  Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA.  Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.  CENPT has a fundamental role in kinetochore assembly and function.  It is one of the inner kinetochore proteins, with most further proteins binding downstream.  Required for normal chromosome organization and normal progress through mitosis.
What are the official names of this protein?
Centromere protein T, CENP-T.
What is the protein family that this protein belongs to?
Belongs to the CENP-T/CNN1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.
Protein: HTPX_SALSV
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGFGGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRSGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNS1G_RATFU
Sequence: MGLEKSFILFSLLVLVLGCVQPSLVGESKESPSEKFKRRHMDEEGPYQSSPTYCNQMMKDRGMTSGRCKPLNTFVHESWAKVKAICSQDKVTCKNGKSNCHKSISTLNITDCLLMGSSKYPKCDYSTTARQKHSIIACDGNPYVPVHYDATV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic gamma-type, RNase 1 gamma.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUB_WOLSU
Sequence: MEANKGKFYHETGGESLKPNALFVGYKPMFMSSNHYLQRLKRRFGVKKAGYSGTLDPFAKGVLVVAFGHYTRLFDHLNQEPKVYRATLWLGLHSDSLDIENILGVEVIPPYSKERVEEIMGALEGEISYTPPKYCAKRIGGRRAYDMARNKEEVELPILTMRVGRLSLLHYTHPFVHFEAEVSKGSYIRSLGGMIASRLGCYGALSSLERLSEGEMRFEGYRELEPLEILPYPKIDATSLKEEFLHGKKLLASDLGNPKEGKYIAEFEEFFSIIEIKEGQVVYLLNRMEKC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: YIDD_BACHK
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGALKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVHS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: URK_STRT2
Sequence: MPKKPIIIGVTGGSGGGKTSVSRAILSNFPDEKIAMIEHDSYYKDQSHLTFEERVSTNYDHPFAFDTDLMIEHINELIAGRPVDIPIYDYTQHTRSNKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKLFVDTDDDIRIIRRIKRDMEERGRSLDSIIDQYNSVVKPMYHQFIEPTKRYADVVIPEGVSNTVAIDLINTKVASILEESKKA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_NANEQ
Sequence: MEVPLYNLQASQVGNIELPPQFNEKIRFDVIKRAFLAIQSHKRQPYGASPIAGKQHSAWTSKRRRSWRTSYGRGISRVSRAILRRHGALFYWVARNIAQAVKGKKAHPPKAEKDWYEKINKKERRLAIRSALAATKELDLVKARGHIIDKPVPIVVDGLEQLRKTKEIQQLLLKLGLEKELERVYEIKRRAGKGKRRGRAYIERKGPLIVVNDYNEQLFKAVDNIPGLDIEEVPNLNVELLAPGAKPGRLLIISKDALETLRERKLFF
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RECO_PELTS
Sequence: MKLYKADAIVLRARDCGEGDKILTLYSREHGRIKAMAHGVSKPTSRKRGAVQPFTRSRFLLRRGRELDTVSQCEGVETFPFLRESLERIGYASYVAELVEALTPEGEPNESLFFLLLDVLRLLAGGDAEMLARAFELKVAALLGYCPVLERCSHCQGALAGPLFFSSSLGGAVCGLCVAFAANPVEVNKGTLEILKALLNWPLARIGLLRVNRRFRNRIRLILRQYLTYHLERDLKSYAFLDRFGQAPAGSGAADV
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL11_CAMJJ
Sequence: MAKKVVGEIKLQIAATKANPSPPVGPALGQQGVNIMEFCKAFNERTKDMAGFNIPVVITVYADKSFTFITKQPPATDLIKKAAGISKGTDNPLKNKVGKLTRAQVLEIVDKKIADLNTKDRDQAAKIIAGSARSMGVEIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SLMA_SALPK
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTSTRLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDENLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y1853_PSYA2
Sequence: MTVQLSNLEHLPNYQITERLDVVYGSTVRSKHVGKDLFAGLKNIVGGELTAYTELLEESRQEAIDRMIVKAEALGADAVVGLRFSTSSIAQGASELFVYGTAVKAVPMQQQPIYQSSNQPPSHHSGHSQYEEPVPSAAQPSTTAQANDDLPRFNPFGE
What are the official names of this protein?
UPF0145 protein Psyc_1853.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: EFP_LEPIC
Sequence: MTLGITEVKKGMVLKVEGDLYSVVKTEFVNPGKGSAFIRTKLKNLTRNSSIERTFKAAEKLESVELEKRNMTICYTEGDDIIFMDSNDFEQMPVSKEYVEDILPFLKEETPMEVTFYEGKPIGVIPPNFSILEVTYAEEGLKGDTSGTAQKRITVETGGEINVPIFVKQGDVIKIDLRDLTYVERVSK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBP3_PHYPA
Sequence: AYGESANVFGAP
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, OEE2, 24 kDa subunit of oxygen evolving system of photosystem II.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: COQ5_ORYSJ
Sequence: MALRSAAGRLASSSRRRLLSPPTSIHTAFLHSHATSFGYKQVAEEDKSKLVGNVFSSVASSYDLMNDLMSVGLHRLWKDRLISKLNPFPGMKHLDVAGGTGDVAFRALERINSVSHRAMQGTLTDIEEETQIYVCDINPNMLNVGKKRASERGYKEGHCLSWIQGDAEALSFEDGSMDGYTIAFGIRNVTHIEKALSEAYRVLKRGGRFLCLELSHVDVPLFKEIYDVYSFSVIPAVGELVAGDRQSYQYLVESIRRFPNQEKFAQMIQEAGFERVEYENLVGGVVAIHSGLKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y355_BUCAI
Sequence: MFLIDSHCHLDRLNYNLPLENIEDVLKKSYQNHVKNFLTVSTCISNFYNIKKLFKKYNTIFYSCGVHPLNCKKELNLFHTIENLSNEIKKLSCIKDVIALGETGLDYYYSSDTKKIQQDFFREHIRVAIKLKKPIIVHSRNASEDTIKILQEENAEKCKGVLHSFTGDYNTACKLLDLGFYISCSGIITFKNSLELCKTIRKIPLNRLLIETDSPYLSPAPYRGKGNQPAYLFYIAEYLSILKEIDIHALGHITTSNFRTLFNI
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase BU355.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: RS10_LEIXX
Sequence: MAGQKIRIRLKSYDHAGLDTSARKIVDTVTRAGATVVGPVPLPTEKNVVCVIRSPHKYKDSREHFEMRTHKRLIDIVDPTPKAVDSLMRLDLPADVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL18_RHOP2
Sequence: MSKLNVTNARRKTRVRIALRRTANGRPRLSVFRSSKHIYAQVIDDLKGETLASASSLEKSMREAGNTGANIDAAKAVGKLLAERAVKQGVKEVVFDRGGYLYHGRVKALADAARESGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ENGB_MESM1
Sequence: MLKFIKSSTKESEWLKNPKNEICFVGRSNVGKSSLINALFKTRVVKVGKTPGKTKLINFFEDERGNSVVDLPGYGYAKLSKEAQSEISDMIFEFLTKRVEIKKLFLLIDSRLGFTPIDQEFYDFLKEAPFEIIIVATKRDKLNQSQTYQIKKSLDELKVKYFLVSITKKEFLQDLVNNLFN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: QUEC_LEPBJ
Sequence: MNSRKDKNSKGKNSDTKRKKSSQENDKAVVLLSGGLDSTTCLYQALADGKKIQALSFDYGQKHKIELSYAKKITRQLGISHTIQKLKPELFLGSSLTQKSLRVPKNSLGKEEIPNTYVPGRNILFLSFAVCLAEGTGSNSIYIGVNAMDYSGYPDCRPEFIKTYETAIQLGTKKGNQGSPIKIVTPLQNLSKKEIVLLGNRLQVPFHLTFSCYDPKNRKACGKCDACLLRKKGFQETGVSEK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.