PharMolix/UniProtQA huggingface dataset:
Protein: PHEA2_SYNPY
Sequence: MKSVITTVVGAADSASRFPSASDMESVQGSIQRAAARLEAAEKLSANYDAIAQRAVDAVYAQYPNGATGRQPRQCATEGKEKCKRDFVHYLRLINYCLVTGGTGPLDELAINGQKEVYKALSIDAGTYVAGFSNMRNDGCSPRDMSAQALTAYNTLLDYVINSLG
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
C-phycoerythrin class 2 subunit alpha, C-phycoerythrin class II alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the periphery of the phycobilisome rod.
Protein: RIB7_KLUMA
Sequence: MVLLPLKKDLVPFLEPYLPDEERDADKEKPYVILTYAQSLDSRIAKIKGTRTFISHEETKTMTHYLRYKFDAIMLGCGTVMIDDPGLNCKWWPEDEKPEHLAGISPRPIILDPNCKWKFADSKMKKLYEAGDGKAPIIVVKELPSEPEEGVDYLVMRTNFTGKMDWSDMLVQLKSKFNVKSVMVEGGGIVINDLLQRPNLVDALIITLGATFLGSEGVEVSPLVEIKLKDVSWWTGDLDTVLCSRLVTH
What is the function of this protein?
Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
What are the official names of this protein?
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, DAROPP reductase, DARP reductase, 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase, 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase, DARIPP synthase.
What is the protein family that this protein belongs to?
Belongs to the HTP reductase family.
Protein: YCCT_ECOBW
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: BIOB_XANP2
Sequence: MTTSTGTTTGTGTARAAEGSLLRSDWTEAEARALYDLPFPELMFRAQSVHRRHFDPTTVETATLLSIKTGGCAEDCGYCSQSAHHETGLKATKLMGVEEVLSQAQKAKDGGATRFCMGAAWRSPKDRDLDAVCAMISGVKAMGLEACVTLGMLTPDQVTRLGAAGLDYYNHNIDTSPAFYPEIVTTRTMDDRLDTLASVRAGGIRLCTGGIVGMGESVDDRIAMLLVLATLDPHPESVPINMWNEIEGTPVMGKADKPDPIAFVRLIALARLLMPQSIVRLSAGRDAMSDEMQALCFLAGANSIFTGDVLLTTANPERDKDAALFARLGIRAAAPAATEMRSAAE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: COAX_PSEPF
Sequence: MILELDCGNSFIKWRVLRAEAGALIAEGVVDSDGALVDNLRSLEKVSLVKCRLVSVRTEDETNLLIGLLKQEFGISVVCAAPAREMSGVKNGYDDYERLGLDRWLAMLGGFHLAKGACLVLDFGTAVTADFISADGEHLGGFICPGMPLMRNQLRTHTRKIRYGDLAAERALTSQAPGRNTVEAVERGCSLMLRGFVLTQLEMARSYWGDDYRVFITGGDAELVSDVAPEARVVSDLVFVGLAMACPLS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPY_ECO57
Sequence: MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKFGPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATAE
What is the function of this protein?
An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding.  Binds substrate over a large region.  Protect proteins in vitro against tannin inactivation; tannins have antimicrobial activity.  Overexpression enhances the stability of otherwise unstable periplasmic proteins (PubMed:21317898).
What are the official names of this protein?
Periplasmic chaperone Spy, Spheroplast protein Y.
What is the protein family that this protein belongs to?
Belongs to the CpxP/Spy family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYGA_PSESM
Sequence: MSQPTPAVRTFQDLILALQQYWAEQGCVVLQPYDMEVGAGTFHTATFLRAVGPETWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVILKPNPDNFQELYLGSLKHIGLDPLVHDVRFVEDNWESPTLGAWGLGWEIWLNGMEVSQFTYFQQVGGIECYPVTGEITYGLERLAMYQQGVDSVYDLVWADGPFGKVTYGDVFHQNEVEQSTYNFEHANVDKLFELFDFYESEAARLIELELPLPGYEMVLKASHTFNLLDARRAISVTARQQYILRVRTLARSVAQAYLQARARLGFPMAPPDLRDEVLAKLEAAQ
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INBVL
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALARPMCVGTIPSAKASILHEVRPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTHNVINAEGAPGGPYRLGTSGSCPNVTSRNGFFATMAWAVPRDNKTATNPLTVEVPYICAKGEDQITVWGFHSDNKAQMKNLYGDSNPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHAKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: ZN343_HUMAN
Sequence: MMLPYPSALGDQYWEEILLPKNGENVETMKKLTQNHKAKGLPSNDTDCPQKKEGKAQIVVPVTFRDVTVIFTEAEWKRLSPEQRNLYKEVMLENYRNLLSLAEPKPEIYTCSSCLLAFSCQQFLSQHVLQIFLGLCAENHFHPGNSSPGHWKQQGQQYSHVSCWFENAEGQERGGGSKPWSARTEERETSRAFPSPLQRQSASPRKGNMVVETEPSSAQRPNPVQLDKGLKELETLRFGAINCREYEPDHNLESNFITNPRTLLGKKPYICSDCGRSFKDRSTLIRHHRIHSMEKPYVCSECGRGFSQKSNLSRHQRTHSEEKPYLCRECGQSFRSKSILNRHQWTHSEEKPYVCSECGRGFSEKSSFIRHQRTHSGEKPYVCLECGRSFCDKSTLRKHQRIHSGEKPYVCRECGRGFSQNSDLIKHQRTHLDEKPYVCRECGRGFCDKSTLIIHERTHSGEKPYVCGECGRGFSRKSLLLVHQRTHSGEKHYVCRECRRGFSQKSNLIRHQRTHSNEKPYICRECGRGFCDKSTLIVHERTHSGEKPYVCSECGRGFSRKSLLLVHQRTHSGEKHYVCRECGRGFSHKSNLIRHQRTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 343.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUI1_THEGJ
Sequence: MPRIVNPLDEMLFKEVLKEQQRIRVYIERARYGKLKTIIEGIDEKEFDLEDIAKKLKAKLACGGTVKKGRIELQGDHRDRIKKLLADLGFSEELIEVE
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: ZDH1_STAAN
Sequence: MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMKVTQAPRVLGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISHNPSENVGKSVLIINGAGGVGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHITTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIELGHYQPTTTQVFEGLSPENLYQAHQLLEKQSMIGKLVINI
What are the official names of this protein?
Zinc-type alcohol dehydrogenase-like protein SA1988.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: DNAK2_PROMP
Sequence: MGKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYTKNQDQLVGQIAKRQAVMNPENTFYSAKRFVGRRVDEVNEESKEVSYGIEKAGSNVKLKCPVLDKQFSPEEVSAQVLRKLSEDAGKYLGENITQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKSNERILVFDLGGGTFDVSVLEVGDGVFEVLSTSGDTHLGGDDFDRCIVDHLASIFKSNEGIDLRQDKQALQRLTEAAEKAKIELSNATQSEINLPFITATPEGPKHLDLNLTRANFEELASKLIDRCRVPVEQALKDAKLSTGEIDEIVMVGGSTRMPAVQELVKRVTGKDPNQTVNPDEVVAVGAAIQGGVLAGEVKDILLLDVTPLSLGVETLGGVMTKMITRNTTVPTKKSETYSTAVDGQTNVEIHVLQGEREMASDNKSLGTFRLDGIPSAPRGVPQIEVTFDIDANGILSVTAKDKGSGKEQSISITGASTLSDNEVDKMVKDAESNASVDKEKREKIDLKNQAETLVYQTEKQLGELGDKVDASAKAKVEEKSKALKEATSKEDYEAMKKLLEELQQELYAIGSSVYQQPGNQPPAPGTPDSNESNDKGGDDDVIDADFTETKD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK2, HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: VF233_ASFWA
Sequence: MILIASPFSLAHLEYLHTWHVTIKNIAQQHGLDIKVAIVVSTSHLNTFLPISTALNIECITFPGCGIKEIDLLWARIKLFQHYCAIGARLLWLVSADIRPPVSTWPAIADSLKKGADAVVIPYPSRWNNLIPTVIKEIVVHQKKCLVAVDARHLDTDTQIVGAGMGCIVLTLKALMVRLSIGKQPIKILWPDLHGTAEGIPLEGVEVGWFLNAYAHKLNIRCLGAEHIAQHFI
What are the official names of this protein?
Uncharacterized protein H233R, pH233R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H233R family.
Protein: PYRF_BACAN
Sequence: MSQSLIVALDFPGKQDVEQFLRHFEGEELFVKVGMELFYKEGPAIITYLKEKGHKIFLDLKLHDIPNTVKSAMRSLASLDVDMVNVHAGGGSSMMKAAIEGLEEGKQEGKERPICIAVTQLTSTSETMMKKEIGIEKTLEEAVAHYAKLTKESGLDGVVCSTLEVPKLREVCGSEFVTVTPGIRLASDDVNDQVRVATPKRARELGSSYIVVGRSITKAENPLEAYKTVKQQWEGVTV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: ZOG_PHALU
Sequence: MALNDKSIPHETKVVVLLIPFPAQGHLNQFLHLSRLIVAQNIPVHYVGTVTHIRQATLRYNNPTSNIHFHAFQVPPFVSPPPNPEDDFPSHLIPSFEASAHLREPVGKLLQSLSSQAKRVVVINDSLMASVAQDAANISNVENYTFHSFSAFNTSGDFWEEMGKPPVGDFHFPEFPSLEGCIAAQFKGFRTAQYEFRKFNNGDIYNTSRVIEGPYVELLELFNGGKKVWALGPFNPLAVEKKDSIGFRHPCMEWLDKQEPSSVIYISFGTTTALRDEQIQQIATGLEQSKQKFIWVLREADKGDIFAGSEAKRYELPKGFEERVEGMGLVVRDWAPQLEILSHSSTGGFMSHCGWNSCLESITMGVPIATWPMHSDQPRNAVLVTEVLKVGLVVKDWAQRNSLVSASVVENGVRRLMETKEGDEMRQRAVRLKNAIHRSMDEGGVSHMEMGSFIAHISK
What is the function of this protein?
May regulate active versus storage forms of cytokinins, and could have an impact on seed growth.  Can also use UDP-xylose to catalyze the formation of O-xylosylzeatin but at much lower affinity.
What are the official names of this protein?
Zeatin O-glucosyltransferase, Trans-zeatin O-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RAH1D_ARATH
Sequence: MASVSPLAKYKLVFLGDQSVGKTSIITRFMYDKFDTTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVANRLSFLNTSKWIEEVRNERAGDVIIVLVGNKTDLVEKRQVSIEEGDSKGREYGVMFIETSAKAGFNIKPLFRKIAAALPGMESYSNTKNEDMVDVNLKPTSNSSQGDQQGGACSC
What is the function of this protein?
Protein transport.  Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) (By similarity).
What are the official names of this protein?
Ras-related protein RABH1d, AtRABH1d.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid- anchor.
Protein: VPK19_HUMAN
Sequence: WASQVSENRPVCKAIIQGKQFEGLVDTGADVSIIALNQWPKNWPKQKAVTGLVGIGTASEVYQSTEILHCLGPDNQESTVQPMITSIPLNLWGRDLLQQWGAEITMPAPLYSPTSQKIMTKMGYILGKGLGKNEDGIKIPVEAKINQKREGIGYPF
What is the function of this protein?
Retroviral proteases have roles in the processing of the primary translation products and the maturation of the viral particle.  Endogenous Pro proteins may have kept, lost or modified their original function during evolution.
What are the official names of this protein?
Endogenous retrovirus group K member 19 Pro protein, HERV-K(C19) Pro protein, HERV-K_19q12 provirus ancestral Pro protein, Protease, Proteinase, PR.
What is the protein family that this protein belongs to?
Belongs to the peptidase A2 family. HERV class-II K(HML-2) subfamily.
Protein: METK_GEOUR
Sequence: MEMKDFIFTSESVSEGHPDKVADQVSDAILDAILTQDPKSRVACETLVTTGMTVVAGEITTNAIVDYPKIVRETIKEIGYNDSAMGFDWETCAVLTSIDKQSPDIAQGVTEGEGLFKEQGAGDQGLMFGYACNETPELMPMSILLSHKLVKKLADVRKSGVLDFLRPDSKSQVSIQYINDRPVHVDTVVISSQHTPEVSYETIKEGIIEEVVKKIIPEELMDAKTRFLINPTGRFVIGGPMGDCGLTGRKIIVDSYGGHGAHGGGAFSGKDPSKVDRSAAYMGRYVAKNLVAAGLCEKCEVQVAYAIGVAEPVSVMVDTSGTGKIPSARIAQIVREVFDLRPRAIIEQLDLLRPIYKKTAAYGHFGRELPEFTWERTDKVSIIREKAGI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_MESM1
Sequence: MKRIISKKSNRIFKPKPCFFHVEKIKYIDYKDVELVSKYINNHGKILSSKITGNCAKHQRLISNVIKRARIMALIPFISERIRK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LACC_STRA5
Sequence: MILTVTLNPSIDISYCLENFNMDTVNRVTDVSKTPGGKGLNVTRVLSQLGDNVVATGLLGGDFGDFIRSGLDALEIRHQFLSIGGETRHCIAVLHEGQQTEILEKGPHITKDEADAFLNHLKLIFDAATIITVSGSLPKGLPSDYYARLISLANHFNKKVVLDCSGEALRSVLKSSAKPTVIKPNLEELTQLIGKPISYSLDELKSTLQQDLFRGIDWVIVSLGARGAFAKHGNHYYQVTIPKIEVINPVGSGDATVAGIASALEHQLDDTNLLKRANVLGMLNAQETLTGHINLTYYQELISQIQVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: FMM1_NEIGO
Sequence: MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTEYYLNHGKWPENNTSAGVASPPSDIKGKYVKEVEVKNGVVTATMLSSGVNNEIKGKKLSLWARRENGSVKWFCGQPVTRTDDDTVADAKDGKEIDTKHLPSTCRDNFDAK
What is the function of this protein?
Major component of the type IV pilus (T4P) that plays a role in cellular adherence, microcolony formation, resistance to neutrophil mediated killing, twitching motility as well as transformation (PubMed:27213957).  Mediates the attachment and the formation of bacterial microcolonies on host epithelial cells.  Mechanistically, pili retractation induces host NF-kappa-B activation in infected cells, which is temporally associated with the formation of gonococcal microcolonies (PubMed:27213957).
What are the official names of this protein?
Type IV major pilin protein PilE1, MS11 antigen, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: NU4LM_ZIPCA
Sequence: MSLVHMNVIVAFTLSLVGLLMYRSHLMSALLCMEGMMLSLFVLAALTILNSHFTLASMMPIILLVFAACEAAIGLALLVTISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CATF_HUMAN
Sequence: MAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRAVLGLVRGRVRRAGQGSLYSLEATLEEPPCNDPMVCRLPVSKKTLLCSFQVLDELGRHVLLRKDCGPVDTKVPGAGEPKSAFTQGSAMISSLSQNHPDNRNETFSSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins.  Has also been implicated in tumor invasion and metastasis.
What are the official names of this protein?
Cathepsin F, CATSF.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: YS84_CAEEL
Sequence: MNMLRCFPECGICGQEYSEDEKLLIPRILTECGHTICTGCAGKIKGQSSIIACPFDRIETRIWKKDVTRLKKNFSILEIKQEVKDRKNRVISEKNEKKERNKNGVCDENTNHHASNYCETCDADLCEECWTWIHSISTLAHHEKKMISTPDCQFHPGKSISLVCMRDRCKKRQNRLMCSECFLDKCSDHFEHEHSSLHLELPELRRNICSSLALYHEKEKKILANIGKLREIIATYSYDGEPFFQKKNELLRFRHFEMGEMDQAIKVLENEVVKRVRVLEYKISNQKLDLDWLQKNKDAIVKLSALPNMKLVQRKWELEVTVKRIEKDSAVRRPEFLADCSTCIVHVLSQRPLQIEMIPAFRLEIRECHRNEVRKFIENHSTRISSRSNILRYNCDFLEIIDRTEDLTIYSEGLRLIMIVDLLDGDRDRYFVALEQLEEAVAYEKIIVGLKSYSRGHGEAASNFLTKLADLHNKMPKITVVVNVDRSEDIEKIVNESII
What are the official names of this protein?
Uncharacterized RING finger protein ZK945.4.
Protein: SYGB_YERPB
Sequence: MTQQTFLVEIGTEELPPKALRSLAESFAANFTAELDNANLSHGEVSWYAAPRRLAVKVANLSAAQADREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLVTDKGEWLLYRAHVKGQPAQLLLAGMVNTALSKLPIPKLMRWGDKETQFVRPVHTVTLLLGTEVIPGTVLGINSDRVIRGHRFMGEAEFTIDSADQYPQILLERGKVIADYELRKSIIKRDAEQAAQQIGGVADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDTAGHLMPHFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFKTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWVAAQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLSLDLQTLTEEAVRLYGSKLTNAKVVDDVIEFMLGRFRAWYQDEGHSVDTIQAVLARRPTKPADFDARVKAVTYFRTLDAAAALAAANKRVSNILAKSTDTLNDHVHASILKEPAELKLATHLVVLRDQLEPVFAAGQYKEALVELAALRETVDEFFESVMVMAEDDAVRVNRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSL_VIBCH
Sequence: MPRQSPPNLAKLIALDLLTVGRVPLLLLVLIFSCAMGVVFMTHHTRQAISAKDQAFMERERLDNEWRNLILEETALAEHSRVQQLARKDLEMKRPDSDKEVVINLK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: YC7C_SCHPO
Sequence: MYESPIILGSKPCTLNIPGMGVLHGLTVLDENGKEKCHRFTGIRYAKPPVGKLRWRRPVTLEDGYDYSGDYNQFKTICPQPFYNNRKNQVRNPDFKYDEDCLFLNIWVPAGEKPAEGWPVLYFIHGGWLQVGNPLHYRQCDPQDLQADGSPAKFILVSPGHRLNLFGFLAGKELLEEDPKSSNFGFWDQRLGLEWTYKHIESFGGNKENIAVGGISAGSYSALFQLIYETYHPEANQIIKRALLLSNGLSVQPKSVEESQIQFNELAQKFGIPLELSSAEKLEKLRAIPFQDLADNILNLRLHTFRAVTDGDFVNPNTFKDIYDGTFGKRIRDSGRELIIGEVNNEHSIYANTNPPKSKEDLFNQVNNYYPEKVTKALLELYPKVPDMEDEKEYLAAIKALFGSIVSDMQVYASTRVLINGLVKGGVPLEKIYRYRIAFRGKFFDKYEPPESLVPHAGDLGLWFYNVVDGILPEEIPIYKAWLKSYGEWMSTGKTDWGTTKTEEYRLLDADGTIKVVDDEKWDWGLKVGRTVAGVFGLN
What are the official names of this protein?
Uncharacterized esterase/lipase C417.12.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRK_BACC7
Sequence: MMQKQNMIVVNQKEIAKNIYELVLQGTLVQQMNEPGQFVHIKVAEGIAPLLRRPISICNVDQEKNEFTMLYRAEGQGTKTLATRKQGEMVDVLGPLGHGFPVEEAEAGQTALLVGGGIGVPPLYELSQRLVAKGVRVIHILGFQTKDVVFYEEKFAELGDTYVATVDGTHGTKGFVTDVIDHYGIDFDILYSCGPLAMLRALEGRYKEKKAYISLEERMGCGIGACFACVCHLQEDPSGHSYKKVCSDGPVFPIGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: PXMP2_HUMAN
Sequence: MAPAASRLRAEAGLGALPRRALAQYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK
What is the function of this protein?
Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.
What are the official names of this protein?
Peroxisomal membrane protein 2, 22 kDa peroxisomal membrane protein.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ACPS_RICAH
Sequence: MLIGVGTDIVQILRIEKILHLYPELFAKRILASKELRQFALLNKTSHATFLAKRFAAKEAVSKAFGIGIGQGINFKDITILNDDLGKPIVEVSASYTKKYSSFNIHLSLSDDYPVCVAFAIVESSC
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DISA_HALH5
Sequence: MDSEVKERFARNILKMVAPGTALRTGIDNVLRAKTGGLIVLGYNENMKGIVDGGFYLDCPFSPASLYELAKMDGAIILNEDGTKILYANTQLNPDNAISSNETGIRHRTAERVAKQTGNLVISISQRRNVITLYHGHLRYALRDIGVILTKANQAIQTLDKYKSVLDQDITDLGALEFEELVTFHEVSQVMQRIHMVLNIKGEILNYVNELGSEGRLITMQLNELVSNLEKEVLLLIQDYAKEDDVDPEDVLEQMMKCSNEELLDDSNILKLLGYHKAFNVQEQQATPRGYRILHKIPRLPATIVRNLVHSFENINDMLRADLKELDEVEGIGEARAKLIKDGLSRIQEQLFMDRNI
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.