PharMolix/UniProtQA huggingface dataset:
Protein: TRXB_MYCTU
Sequence: MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADSTDALIGAQR
What is the function of this protein?
Essential thiol-reducing enzyme that protects the cell from thiol-specific oxidizing stress.  Plays a minor role in defense against oxidative and nitrosative stress.  Is essential to establish and maintain infection in mice.
What are the official names of this protein?
Thioredoxin reductase, TR, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_WOLPM
Sequence: MKLFVHLVLFISLFIPYFTKAALYVDIKKSSVGNIGLVVSKCTCKTALESELSENIAKVIGTNLSNCGLFNVKRSAEAESKSWKSDTVVTVSLSEISGSALELSFRLFDAFTKRELLTQSVVFPAKDWRKIGHLVSDVIHDRLIGEKGHFNTKITYIAEEKDSNYKSVRKIAVMNQDGSNIKYLTNGDRFVSTPRFSPNGKGIVYISYANGKSYIILKNLKDNTESIISAFEGVVSAPRFSPDGKSLLISHSLGGETNILSLDLSSKRTKKITKGSAISTSPSFSPDQKYMAFSSDISGSQQLYVIDFTNKSKKPKRISFGSGRYATPVWSPKGDLIAFTKIQSGKFYIGVMKPDGKEERLLSEGHKIESPAWLPNGREIIFTRTESPSNSKLYLVDLVKKNQKMVSTPTNASLPDWSYF
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FPG_BURVG
Sequence: MPELPEVEVTRRGIAPFVAGRRVERVDVRTAMLRWPVPADLAEQLRAREVLAVERRGKYLLFEVDAGWFIVHLGMTGTLRVLPVAGVPVAAKHDHIDWIFDEFVLRFRDPRRFGAVLWHPREAGDVHAHPLLASLGVEPFSPAFTGALLHARTRGRTVSVKQALLAGDMVVGVGNIYASESLFRAGIRPTTAAGKVSLPRYERLADAVRATLADAIERGGSTLRDFVGSNGESGYFQLDCFAYDRAGLPCRVCGTPIRQIVQGQRSTYFCPTCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: BR1B_RANLU
Sequence: FLPMLAGLAASMVPKFVCLITKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.
What are the official names of this protein?
Brevinin-1Lb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: BMF_HUMAN
Sequence: MEPSQCVEELEDDVFQPEDGEPVTQPGSLLSADLFAQSLLDCPLSRLQLFPLTHCCGPGLRPTSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAVLPIGEQPPEGQWQHQAEVQIARKLQCIADQFHRLHVQQHQQNQNRVWWQILLFLHNLALNGEENRNGAGPR
What is the function of this protein?
May play a role in apoptosis.  Isoform 1 seems to be the main initiator.
What are the official names of this protein?
Bcl-2-modifying factor.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
Protein: URE22_BRUSU
Sequence: MAKEPTKAAHPQPEQTKTNHKAHRPVGGYVLAKDPIEINQGRPRTTLTVRNTGDRPIQIGSHFHFFEVNRYLEFDRSKAFGLRLDIPANTAVRFEPGDEKEVTLVPFAGKRFIFGFNNLVDGWSGDGPTPDYQPNREIAAERAEKLGFKSCKSGGKDAK
What is the function of this protein?
Disrupting the ure2 operon has no effect on urease activity, or pathogen survival in BALB/c mice when inoculated by gavage, but confers slightly enhanced resistance to low pH killing in vitro.
What are the official names of this protein?
Urease subunit beta 2, Urea amidohydrolase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_RICPU
Sequence: MKQIINPLKGNNNKIPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVSKATEVTLQPIKRYGFDAAIIFSDILVLPHALGWEVDFKENIGPILKQFKSQEDFKYLQINPNYKLEKVYEIIKKVKKELPSPISLIGFAGSPWTVMSYMLEGKGKQDFKTSKKFIYENKILAEELLNFITEKTADHLINQAKSGADVLKLFDSWSGVLAEEEFTEFVIEPTKKIVLKVKEVFPKTPIIAFPKGAGLLYEKFIKEVPIDVLAVDQMVPLEKMKEWSDKVIVQGNLDPVVLLTNKEIIKEKTYKILQAMKGKNFIFNLGHGILPETPTENVEFLTEYVRLYEEKNSNSTF
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_NEIMA
Sequence: MPANLSSALETFKQQRDAAEAHYLKANRVSVFFREYTAAVETLLAALWAEYFQNSALCLMAVGGFGRGELYPCSDVDLAVVSPAPLSDGIQEQIARFVQTLWDCKLMPSVKSGSVDELCESVRNDITGDTAFLEARFLFGNRQTADKLAEKMNAQRNVAAFVEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLATDLPDLLKQRILTRAEAGMLSHGYRRLAHIRIHLHLNAKRAEDRLLFDLQPQVAESMGYEGLNLRRQSEELMRVFYRAIKTVKQLSGILTPMLRSRVSSAPMRVTLRIDDDYIQVNNQIAARHTDIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNSENRHRFAGFFRNGNGLTQTLRFLNLYGVLGRYLPAWEKIVGLLQHDLFHIYPVDDHILTVVRNVRRLALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAIQGIADARQFAADHFLTGEESDLLAWLVENHLLMSAVAQKEDIQDPDVLDAFCKRVQTHERLSALYLLTISDIRGTNPKLWNAWRASLLESLFHAAGRYLTGNGGNPHTLFGRRRQEAADLLTRAAVPEKQQKKLWNALGSAYFARHQSREILWHAANLVHDFETPIVRSRILFKSDSFQVMVFMPNGPRLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAELNSFIHGHTVAETQSHSRRISRRSRYMPIAPSITITPEEDYPDWYSVEITAVNRPFLLADMAEVFFAHNVSLRYAKISTLDERAEDSFTVFSLDLKNPKIQSSLKQTLLEQLS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: EV164_ASFK5
Sequence: MYHPVVQVLIGLILVIILILGFYHLKKKSCKTDTDCKDNGHHCVRGTCTDISCLEAVKQDIKGINLDPSIRSCNYTPGFYTFNSTTADLQSPFGKTRIYYGDVYATWSSVDYCQSLCLQHNGCIAWEFDDEKESPGQGSCYFYTNSHPALKNSNDTTIMGIARNIL
What are the official names of this protein?
Putative membrane protein 164.
What is the protein family that this protein belongs to?
Belongs to the asfivirus envelope protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: PYRR_STRPJ
Sequence: MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: GATC_DROWI
Sequence: MLRISNKIRFYCKIAAKSDLKSKLDFTQLRHPTKVPQQPEPNAFPDLDNNTDDDPIDSKTIQLLERLSLVDLDSEEALKTLKSSIQFANRIVDIPTENVPALYTVLEKQQLQLRNDSVTEGNCRQEILRNAKITDEDYFVSPPGNIPLEQQNE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFG_FRAP2
Sequence: MPRNTALEKYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWSGMDQQFDKHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQANKYGVPRIVFVNKMDRSGADFERVCGQIRTRLKANVVPVQLNIGAEEDFKGVVDLIRMKAIMWNEADQGLTYDLVDIPAELQDRAEELRMEMMEAAAEASEELMDKYLEEGELSNEEIKQGLRARVLANEIVLAFCGSAFKNKGVQAVLDGVVEYLPAPNQVPAIKCETEDGEPASRSSSDDEPFAALAFKLATDPFVGNLTFIRVYSGVLKSGDAVYNPVKGKKERVGRIVQMHANKREEIKEVRAGDIAACIGLKDVTTGDTLCDLDKPVILERMDFPEPVISVAVEPKTKADQEKMSIALGKLAAEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFKVEANVGNPQVAYRETIRGTVEQNSKFVRQSGGRGQYGHVVVKFEPLEVSTNDAGEEKIFEFVDEIVGGVIPKEFIGPVAKGIEEQMTNGVLAGYPMIGVKATLFDGSYHDVDSSEMAFKIAGSMALKEGAKKANACILEPIMKVEVVTPEDYLGDVMGDLNRRRGIIEGMDENPSGRVVSALVPLAEMFGYATNVRSMSQGRASFSMEFKKYAEVPNNIADEIIKSRNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCA13_CHICK
Sequence: MRVKVLSRNPDDYVRETKLDLQRVPRNYDPALHPFEVAREYVRALNATKLERVFAKPFLSSLDGHRDGVNCMAKHPKSLSTVLSGACDGEVRIWNLTKRQCIRALQAHEGFVRGMCARFCGTSFFTVGDDKTVKQWKMESPGYGEEEEPIHTILGKTVYTGIDHHWKDAVFATCGQQVDIWDEQRTSPMCSLTWGFDSISSVKFNPIETYLLGSCASDRNIVLYDMRQSTPLKKVILNMRTNTLCWNPMEAFIFTAANEDYNLYTFDMRFLTSPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSVRIFPVDKGHSREVYHTKRMQHVITVKWTSDSRYILCGSDEMNIRLWKANASEKLGVLAPREKAAMNYNQKLKEKFQHHPQIKRIARHRHLPKSIYCQIKEQRIMREARRRKELNRRKHSKPGSVPVVSEKKKHIVAVVQ
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 13, WD repeat and SOF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF13/WDSOF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component.
Protein: ZN683_MOUSE
Sequence: MKALDGLRESLYPSLDFQLYQDDQVCSADASQPLADSVGAHDLAWSERMCPLPLAPAKSPLLACPESPDLCLCALQKTPLGRAPQDLGEDASNMRHQPPSLYKASTDSEKLTIKDSLNREEMGNEPERGAYPHLPPRTSSFPDAGLDRKSLSPLTFWPWLPPTLISKEPPIHIYPIFPGYPLLPLPYLFTYGALPSAQHPYLFMLPPHSTYPTVAGPSLLMTASGSGPRIPQEKTLLLHSGAFQSAGHTLHSQVESRSSRDTRTPGQAGVAAPTRRAVPGSRAGVIALPYPLKKENGKILYECNVCGKNFGQLSNLKVHLRVHSGERPFQCALCQKRFTQLAHLQKHHLVHTGERPHQCQVCHKRFSSSSNLKTHLRLHSGAKPSQCGLCPSYLTPNVYPKLHHRLRAPQLRGLTHTHLPLASLTCLAQWHQGALDLVEKKMGWTVDKVSSESKGKQG
What is the function of this protein?
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs (PubMed:22885984, PubMed:27102484).  Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T-cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (PubMed:22885984, PubMed:27102484).  Also plays a role in the differentiation of both thymic and peripheral NKT cells (PubMed:22885984).  Negatively regulates the accumulation of interferon-gamma (IFN-gamma) in NKT cells at steady state or after antigenic stimulation (PubMed:22885984).  Positively regulates granzyme B production in NKT cells after innate stimulation (PubMed:22885984).  Associates with the transcriptional repressor PRDM1/BLIMP1 to chromatin at gene promoter regions (PubMed:27102484).
What are the official names of this protein?
Tissue-resident T-cell transcription regulator protein ZNF683, Homolog of Blimp-1 in T-cell, Hobit, Zinc finger protein 683.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPS_STRMU
Sequence: MIIGHGIDLQDIAAVQRAHERSSRFASKVLTFKELEIFTSLKGRRQVEYLAGRWAAKEAFSKAYGSGIGSLRFQDLEILANNKGAPIFTKSPFSGNIFISISHSKNYVEASVILEENNL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH4_BOVIN
Sequence: MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH.  May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis.  It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
What are the official names of this protein?
Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ATPG_MYCGA
Sequence: MASMQDLKRRMESITVTHKITKAMKMLSTVKLNRFKATLGKTKEFYQEFYEVIGAVITNYNKTKPRTTTPTNQSTKRLWIVINTQLGLCGSYNTNVGKLLVSELAKDDEIILVGTKLNSFLRTRNHEDQIIHTYSINDKNIDFESSYMIGKHVLELHEKNQYDSIDCVYTNYINSLNFEAKKIQLIPADPSIFQADTLDRINDKFPKNISFEPGVDVIIPALEKQLLQVILYGCLIESKVCEYASRRNAMDTAAKNADDLYNKYKLLYNQLRQAKITQEINEIVAGAAK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYB_CARPS
Sequence: MTNIRKTHPLLKIVNSSFVDLPAPSSLSSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFVVAALVMVDLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLVMLTALSTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPMLHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQMASVLYFLIILVLMPLTSIVENRLLSW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRUB_CAMJE
Sequence: MNKIFAAFKPRGLSSNAFLSTLKKKYKNKKAGYSGTLDPFAKGVLIVAFGQYTKLFRFLKKTPKTYKATLWLGVYSLSLDDQNIKEIKNIKEFDLPNLQQIIDQMQGIISYTPPQFSAKRINGTRAYELAKKGIEVNLKPCQMEVFDCKILSYNHPFLNIEITVSEGAYIRSYCELFARKLGINATLSSLERIKEGKFVYNNEKSLNVLKYINLKPNFIKDLNKLENGAKIFVEELEFHDKGDYYIETEKYFSIINIKENTVKYLLNKVEKC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BSHC_CHLTE
Sequence: MNTFLIDYQRIRTPKKGFSKLFCDYSSESEARTKLLADCFHLDYRKDGDYYRHLGFLASRNFRREALVELLTEQNERFDGSERQQREIEKLRSPRCMAIVTGQQTGLFTGPLYTIYKALTAVVLARKQKELFPEYDFVPVFWIESEDHDFDEASSTVLFSGGGLEQITAEAAHRLPDQMAGATQLGASIGATVQEFLDLLPDTEFKPEIAEILESCYEPGVTFEIAFARTMNRLFREHPLILLSAQDTRFKQLAVEVLCREVETAPASSYDVVAQSSILESMGYPAQTKPRAVNLFYLNQLGQRLKIEQPSPDNFLIVPDRQRYTRHQLLEICQDHPEKFSPNVILRPIVQDAVLPTFAYIGGPGEISYLAQFRKAYEHFGLSMPFVIPRGSFTLVEPKIARTMDKVLKATGRPSFSRRQVYEAVFEDVQELRKSMVSGGDSQKLDALFEQVESEVTRSLSTLEPALVKMDPTLQAALSASSGQITKIIGTIKEKTYRAGRRKHDELLQQLDKAELNLFPDGKPQERSINIFHYLNKYGPSLIGELAKVLQGYSTEAHLIVEL
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: Y3610_MYCBO
Sequence: MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAAKRARAQPRRPVKRADETETVLGRNPVLECLRAGVPATALYVALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDLLAAALDQPPALLVALDNLSDPRNLGAIMRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAAIARQRRRPREPREQTQNRMI
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase Mb3610c.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: SPT22_HUMAN
Sequence: MKRSLNENSARSTAGCLPVPLFNQKKRNRQPLTSNPLKDDSGISTPSDNYDFPPLPTDWAWEAVNPELAPVMKTVDTGQIPHSVSRPLRSQDSVFNSIQSNTGRSQGGWSYRDGNKNTSLKTWNKNDFKPQCKRTNLVANDGKNSCPVSSGAQQQKQLRIPEPPNLSRNKETELLRQTHSSKISGCTMRGLDKNSALQTLKPNFQQNQYKKQMLDDIPEDNTLKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYEIDRELPRLIRGRVHRCVGNYDQKKNIFQCVSVRPASVSEQKTFQAFVKIADVEMQYYINVMNET
What is the function of this protein?
Meiosis-specific protein required for homologous recombination in meiosis I.
What are the official names of this protein?
Spermatogenesis-associated protein 22, Testis development protein NYD-SP20.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on MEIOB.
Protein: EMTA_SALCH
Sequence: MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: PLSY_ANAMF
Sequence: MNLLMGYTYLIPILFASYLIGSIPFSWILVKVFYKRDLRSVGSGNIGATNAFRVNRGISFLVLLLDIFKSVLVILILEKMCAHKSIMYLTGFTVVLGHIFPVWFLFKGGKGIAPTIGVVLSINIKIFFLFIITWAVVFMIFRYSSLSSIISIISSCIYCAVTENFNSSIFYIAMSIIVLIKHRDNVIRMINGTEKKLF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRC2_ARATH
Sequence: MECRSLDLTIISAEDLKDVQLIGKQDLYAVVSINGDARTKQKTKVDKDCGTKPKWKHQMKLTVDDAAARDNRLTLVFEIVADRPIAGDKPVGEVSVPVKELLDQNKGDEEKTVTYAVRLPNGKAKGSLKFSFKFGEKYTYGSSSGPHAPVPSAMDHKTMDQPVTAYPPGHGAPSAYPAPPAGPSSGYPPQGHDDKHDGVYGYPQQAGYPAGTGGYPPPGAYPQQGGYPGYPPQQQGGYPGYPPQGPYGYPQQGYPPQGPYGYPQQQAHGKPQKPKKHGKAGAGMGLGLGLGAGLLGGLLVGEAVSDIADMGDMGDMGDMGGFDF
What is the function of this protein?
May act as an activator of the calcium-dependent activation of RBOHF that mediates reactive oxygen species (ROS) production and may play a role in cold responses.
What are the official names of this protein?
Protein SRC2 homolog, AtSRC2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Protein storage vacuole membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Note=Binds to C-terminal sequence of alpha-TIP and moves from the ER to vacuoles. Movement is accompanied by membrane internalization, and SRC2 is present in crystalloid-like structures within protein storage vacuoles (PSVs) in mature seeds.
Protein: IF4A_LEIBR
Sequence: MSQQDRVAPQDQDSFLDDQPGVRPIPSFDDMPLHQNLLRGIYSYGFEKPSSIQQRAIAPFTRGGDIIAQAQSGTGKTGAFSIGLLQRLDFRHNLIQGLVLSPTRELALQTAEVISRIGEFLSNSAKFCETFVGGTRVQDDLRKLQAGVVVAVGTPGRVSDVIKRGALRTESLRVLVLDEADEMLSQGFADQIYEIFRFLPKDIQVALFSATMPEEVLELTKKFMRDPVRILVKRESLTLEGIKQFFIAVEEEHKLDTLMDLYETVSIAQSVIFANTRRKVDWIAEKLNQSNHTVSSMHAEMPKSDRERVMNTFRSGSSRVLVTTDLVARGIDVHHVNIVINFDLPTNKENYLHRIGRGGRYGRKGVAINFVTEKDVELLHEIEGHYHTQIDELPVDFAAYLGE
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Probable eukaryotic initiation factor 4A, eIF-4A, ATP-dependent RNA helicase eIF4A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.