PharMolix/UniProtQA huggingface dataset:
Protein: MT1_CASGL
Sequence: MSSCGCGSGCSCGSGCNCKNPVLGLSEKTTSKTIVADVAPVKSHPEGSEMSVEGGHGCKCGSSCNCDPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: OST4_DROYA
Sequence: MISDVQLAIFSNVLGVFLFLLVVAYHYINANTGKPSAKAK
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: MOAA_CAUVC
Sequence: MTPYDDSPAQAVSTAPRTTGPSLIDGFGRAVTYLRVSVTDRCDLRCVYCMAEHMTFLPKAEVLTLEELDRLASTFVGLGVRKLRLTGGEPLVRKGFIGLVARLSRHLSSGALDELTLTTNGSQLERYASDLARHGVRRINVSLDTLKPALFRALTRGGDVTRVIAGIDAAQAAGMTVKINAVALKHDNAGEIPALIQWAHGRGCDITLIETMPLGEVDQDRTDQFLSLQDVRRDLSSFWTLTDIPDSTGGPARYVHVAETGGRLGLITPLSNHFCDTCNRVRLTCTGTLHTCLGRDDASDLRAEIRRGASDAELVDAIHLAIGAKPKGHDFQIAAAQPAVARHMSTTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: Y2265_MYCTU
Sequence: MGANGDVALSRIGATRPALSAWRFVTVFGVVGLLADVVYEGARSITGPLLASLGATGLVVGVVTGVGEAAALGLRLVSGPLADRSRRFWAWTIAGYTLTVVTVPLLGIAGALWVACALVIAERVGKAVRGPAKDTLLSHAASVTGRGRGFAVHEALDQVGAMIGPLTVAGMLAITGNAYAPALGVLTLPGGAALALLLWLQRRVPRPESYEDCPVVLGNPSAPRPWALPAQFWLYCGFTAITMLGFGTFGLLSFHMVSHGVLAAAMVPVVYAAAMAADALTALASGFSYDRYGAKTLAVLPILSILVVLFAFTDNVTMVVIGTLVWGAAVGIQESTLRGVVADLVASPRRASAYGVFAAGLGAATAGGGALIGWLYDISIGTLVVVVIALELMALVMMFAIRLPRVAPS
What are the official names of this protein?
Uncharacterized protein Rv2265.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S22AF_HUMAN
Sequence: MEVEEAFQAVGEMGIYQMYLCFLLAVLLQLYVATEAILIALVGATPSYHWDLAELLPNQSHGNQSAGEDQAFGDWLLTANGSEIHKHVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYSYRRLGEEALSLQALDPQQCVDKESSLGSESEEEEEFYDADEETQMIK
What is the function of this protein?
Probably transports organic cations (By similarity).  Appears not to be the agmatine transporter.
What are the official names of this protein?
Solute carrier family 22 member 15, Fly-like putative transporter 1, Flipt 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SRSF9_MOUSE
Sequence: MSSGWADERGGEGDGRIYVGNLPSDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTYGGRGGWPRGARNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGMGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY
What is the function of this protein?
Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.  Represses the splicing of MAPT/Tau exon 10 (By similarity).
What are the official names of this protein?
Serine/arginine-rich splicing factor 9, Splicing factor, arginine/serine-rich 9.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL4_HALLT
Sequence: MNATVHDLDGGDAGSVELPAIFETAFRPDLIGRAVSAAQANRKQAYGADEFAGLRTPAESFGSGRGLAHIPRSENVARRVPNAVSGRAAHPPKAEKDQTKSLNDKERQLAIRSAIAATADAETVAERGHAFDEDLDLPLVVSDEFEDLNKTQEALGVLEAVGADADIERAEEGRSVRAGRGKTRGRKYSQPKSVLVVTSEEPSRAARNLSGVDVATAREVNAEDLAPGAHPGRLTLWTESAIEEVADR
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS17_STAAC
Sequence: MSERNDRKVYVGKVVSDKMDKTITVLVETYKTHKLYGKRVKYSKKYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RPOA_EHRRG
Sequence: MIFDEDSSSVAQESGYMGVGSPYSSDVGRISMSDHWNKLTKPSSIKVVNHGNALNKADLIIEPLESGFALTLGNALRRVMMSSLRGFAVYGVEIENVLHEFTSISGVREDVTDILLNISMIRLKLSGMDNKVLSLKVKGPCEVRSGMIADTPDCTILNKDLLICTLDQDVDFNIKMYVNSGKGYVPAVKRKSINKFGLSDVPVNFIATNALYSPIKKASFRVESSRIGQFTDYDRLIMSVETDHSILPDEAVALAARILQDQFQQFINFDETDEPHQKVDTKDVLPYDSNLLRKVDELELSVRSYNCLKNDNITYIGDLVQKTESDMLRTPNFGRKSLNEINELLASMNLHLGMKIANWPPESIESLSKQYSEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SASF_STAA8
Sequence: MAKYRGKPFQLYVKLSCSTMMATSIILTNILPYDAQAASEKDTEITKEILSKQDLLDKVDKAIRQIEQLKQLSASSKEHYKAQLNEAKTASQIDEIIKRANELDSKDNKSSHTEMNGQSDIDSKLDQLLKDLNEVSSNVDRGQQSGEDDLNAMKNDMSQTATTKHGEKDDKNDEAMVNKALEDLDHLNQQIHKSKDASKDTSEDPAVSTTDNNHEVAKTPNNDGSGHVVLNKFLSNEENQSHSNRLTDKLQGSDKINHAMIEKLAKSNASTQHYTYHKLNTLQSLDQRIANTQLPKNQKSDLMSEVNKTKERIKSQRNIILEELARTDDKKYATQSILESIFNKDEAVKILKDIRVDGKTDQQIADQITRHIDQLSLTTSDDLLTSLIDQSQDKSLLISQILQTKLGKAEADKLAKDWTNKGLSNRQIVDQLKKHFASTGDTSSDDILKAILNNAKDKKQAIETILATRIERQKAKLLADLITKIETDQNKIFNLVKSALNGKADDLLNLQKRLNQTKKDIDYILSPIVNRPSLLDRLNKNGKTTDLNKLANLMNQGSDLLDSIPDIPTPKPEKTLTLGKGNGLLSGLLNADGNVSLPKAGETIKEHWLPISVIVGAMGVLMIWLSRRNKLKNKA
What are the official names of this protein?
Surface protein F.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Distributed in a discrete, punctate pattern with up to 3 loci per cell over the surface (PubMed:18800056). Does not localize with ClfA (PubMed:18800056). Exchanging the ClfA and SasF signal peptides retargets the mature protein on the cell surface (PubMed:18800056). Anchored to the cell wall by sortase A (Probable).
Protein: GLGB_SYNR3
Sequence: MALATLDWMSKDAERLAQCNHDHPQAVLGPQQLEDGRWVVRVWMPEASRVVLLHQGHEHALENPHHAWIFEGELSSNPGSQYRLRVERAGITHEQHDPYAFRQEWMGAMDRHLFAEGNHHHIWQRMGAHPHLQDGVAGVQFCLWAPNARSVSVIGDCTNWDGRHLPMQQRIGGIWELFVPGLGAGAHYKYEIHTQQGHCYEKADPYGFQHEVRPAQASVVASLKGYQWGDDAWLKQRDNRNPLEQPVSVYEMHMGSWMHGSWDEPYIEADGTPRAPVPAADLKPGARLLTYPELADRVIPYVKARGFTHIELMPMAEHPFDGSWGYQVTGFYAPTSRFGTLDEFRAFVDRCHAEGIGVILDWVPGHFPKDAHGLAFFDGSHLYEHGDPRIGEHKEWGTLIFNYSRNEVRNFLVANLVFWFEELHIDGIRVDAVASMLYRDYLRPDGEWIANEHGGRENLEAVRFLQQANSVLFHYFPGALSIAEESTTWPLVTMPTSMGGLGFNLKWNMGWMHDMLDYFELDHWFRQFHQNNITFSIWYAHTENFMLALSHDEVVHGKSHLLHKMPGSDELKFANVRALLTYMWTHPGKKTIFMGMEFAQRGEWNVWGDLEWDKLQFPEHQGVVNLVDDLNALYKSEPALWRNDFDSFGFQWIDCDDTNHSVVSFMRRDEKEGNWVVVVCNFTPEGHGNYRIGVPVDGFYTELFNSDGARYGGSNQGNLGGKFSDDWGMHSYGQSLDLCLPPLTVMVFKHDPNRQREAAKDEAAAKLGGSLG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RL15_BACAH
Sequence: MKLHELKPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRLGFEGGQTPLFRRLPKRGFTNINRKEFAIVNLSTLNRFEDGTEVTPELLLETGVISKLNDGVKILASGAVEKKLTVKAHKFSSSAKEAIEAAGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: COFG_HALMA
Sequence: MIPGTDAYDIAIEISDADIERLLSVMPEDVEAASALSYCRNVFLPLTTACRYTCTYCTYYDPPGQAELMDREEIRETCRRGADAGCTEALFTFGDDPDDRYTAVHDQLAEWGHDSIHEYLREACEIALEEGLLPHANPGDQTREQMAHVADLNASMGVMLETTTEVQAHGGPRAKNPGQRLNTLRVAGELGVPFTTGILVGIGEDWHHRAESLLAIREMHERYGHIQEVIIQPVVENERWQGGSPDLATMRRVTAMARAALPEEVSVQVPPNLAPARDLTDCGIDDLGGVSPVTVDHINPEYEWPALQELTAVAEAAEVPLSERLPVYDHFVDDGWLSAPIEAAIEADNDAGDRFRSILDRGVNPVTL
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: CASP1_ORYRU
Sequence: MEHGEISSKAPLVAPVAAGVNRAVAVVDTFLRFIAIIGTIGSAIAMGTTNETLPFFTQFIQFEAKYSDLPSFTFFVAANAVVCTYLVLSIPLSIVHILRPRARYSRLFLVFFDTAMLALLTAGASAAAAIVYLAHKGNVRANWFSICQQFDSFCERISGSLIGSFAAMVLLVVLITLSAFALARRH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, OrCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: TAM_YERP3
Sequence: MQDWDPDLYRQFEAERTRPATDLLAHITITSPQFISDLGCGPGNSTELLHRRFPDAQLVGIDHSQAMLASAQQRLPHCTFVEADIHQWHPSQPQNLIYANASLQWLTDHPHLFPSLLSQLAPKGVLAVQMPDNLDQPSHRAMREVAENGPWQQTLQEAGATRAKVLSANHYYDLLAPHAERVDIWRTTYYHPMPSAQAIVDWLRATGLRPYLAPLTEAMQLAFLQNYLAIIDKAYPARTDGRRLLAFPRLFIVAHAQR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2DH_PHANO
Sequence: MFSYLPRYPLRAASARALVRATRPSYRSALLRYQSSEAVGRTQEIVPGAYQIPPRDFSRQHEEKLAPKNAARAPRRIEPATLKLNSKNLSQLQNVTVPTYQREGVKQGIVHVGVGGFHRAHLAAYVDTLLEQFNSQDWSICGVDLQPFAAPMRDALGSQDNLYTMIECDTEGTSARVIGSITDYLFAPDNCEAVIAKMAHPDTHIVSMTVTESGYYMNENTHELQIDHPDIAADLAGQQPPRTVFAYLYAALARRHAAGLRPFTVMSCDNMQKNGDISRNMLLAFARQQNPEVADWIAENGAFPNSMVDRITPRTSDENKAQLAQEFGVEDSWPVVTEVFHQWVLEDKFADGRPPFEKAGVQVVPNVHKVEEYELIKLRLLNASHSAMGYAGYLGGFTYIHEVIADPTFRKYIRNMMQEEVQPLLPRIPGVSVDDYCNTLLGRFSNPTLKDELPRICLGGSGKIPQFIMPSIAEQIQAGGPLRRLTLCAAAWFRYLRGINEQGQAFKLDDPMAEELQAKALESPFSVLEVKSLFGDDLRDDKRFVAELKNALESLERDGARATIAQYA
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: TPIS2_RHIEC
Sequence: MNPMQADAKQLLQEFKQLLQENEITEEKCNIGLAPVTLALTSTQAELANAARSVFTVAQDVSRFGNMGAYTGEVSAELLKDSQIEYVLIGHSERREYFAESAAILNAKAQNALNAGLKVIYCVGESLEQRESGQAEVVVLQQICDLASVVTAEQWPHIVIAYEPIWAIGTGKTASPEDAQTMHAKIREGLTQITSHGANMAILYGGSVKAENAVELAACPDINGAL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_CORGL
Sequence: MTTEVELVVLADSEGNPIGTAPKATVHTKDTPLHFAFSTYILNPRGELLVTRRALSKKTWPGVWTNSMCGHPGPDETNADAIRRRGVDELGLEVDSFLDIQEILPDYQYRAVDASGIVEWELCPVHLVRLAVGEFVEPLDDEVEEFEWAEPQKLFDAVDATPFVFSPWLVDQLSAPELRQAILEAFDAE
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y894_CROS5
Sequence: MAGHSKWANIKRQKERVDAKKGKTFAQLSRAIIVAAKHGIPDPAGNFQLRTAIEKAKAAGIPNDNIERAIAKGAGTYENDDTVYEEIRYEGYGVGGVAILIEAFTDNRNRTAADLRSAFNKNGGNLGETGCVSWMFEQKGVVRIEGNIDENALLEASMEGEADSYELYEEDDDQAAEVFTEMTNLDTLSQTLNDKNFNVTEVELRWIPNNLIYIENDEQAKSIIKLIEALESLDDVQNVTTNFEMADELMLLTVES
What are the official names of this protein?
Probable transcriptional regulatory protein cce_0894.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_VIBC3
Sequence: MPKMKNNKGAAKRFKKTAGGIKYKHATKRHILTKRTTKNKRQLRPNAILPKCELAAVARMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CRYAA_CERSI
Sequence: MDIAIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRSVLDSGVSEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQTALSCSLSADGMLTFSGPKIPSGMDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: EHD4_HUMAN
Sequence: MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKAD
What is the function of this protein?
ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis.  Plays a role in early endosomal transport.
What are the official names of this protein?
EH domain-containing protein 4, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS5_SYNSC
Sequence: MTDSSPQSNPNAVPGAADVPAAAEGQQQQEQRRGRGDRDGRRGDRRGGRRGQERDSEWQERVVQIRRVSKTVKGGKKMSFRAIVVVGNEKGQVGVGVGKAGDVIGAVRKGVADGKKHLVKVPLTRHNSIPTLSNGRDGAASVLIRPAAPGTGVIAGGSIRTVLELAGIKNVLAKRLGSKTPLNNARAAMVALSLLRTHKETAKERGISLEQIYS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DNAK_SHEFN
Sequence: MGKIIGIDLGTTNSCVAVLDGGKARVIENAEGDRTTPSIIAYTDDEIIVGQPAKRQAVTNPTNTFFAIKRLIGRRFKDDEVQRDVNIMPFKIIGADNGDAWVESRGNKMAPPQVSAEILKKMKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGIDKKQGDNIVAVYDLGGGTFDISIIEIDSNDGDQTFEVLATNGDTHLGGEDFDNRMINYLADEFKKDQGLDLRRDPLAMQRLKEAAEKAKIELSSTNHTEVNLPYITADASGPKHLVVKITRAKLESLVEDLIQRTLEPLKVALADADLSISDINEVILVGGQTRMPKVQEAVTNFFGKEPRKDVNPDEAVAVGAAIQAGVLSGEVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTKAQQVFSTADDNQSAVTIHVLQGERKQASANKSLGQFNLEGIEPAPRGQPQVEVMFDIDADGILHVSATDKKTGKKQNITIKASSGLSDEEVEQMVRDAEAHADEDAKFEELVQARNQADGLAHSTKKQVEEAGDALASDEKEKIEAAIATLETAIKGKDKEAIDTATQALIEASAKLMEIAQAKAQGEAEGQAHDAGQEKPADDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: WIR1B_WHEAT
Sequence: MASHSAAGRRPTALVHIALFVAIAAVIINSSVCLGAAVHDAATSGTGALDPNVPAVPTPGGAGQPYTGRGCRTVYGCKPPAGSQP
What is the function of this protein?
Associated with pathogen defense.
What are the official names of this protein?
Protein WIR1B.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: FOXG1_HUMAN
Sequence: MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
What is the function of this protein?
Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
What are the official names of this protein?
Forkhead box protein G1, Brain factor 1, BF-1, BF1, Brain factor 2, BF-2, BF2, hBF-2, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, HFK1, Forkhead-related protein FKHL2, HFK2, Forkhead-related protein FKHL3, HFK3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHNW_BURMS
Sequence: MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFTPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: RGS10_CAEEL
Sequence: MSLAVFSPCDVASKLLSEVVGEKYPKVDDDDSIVEPVTSLCLPQLSYEDFHHFSVIPLWNKTFPCRLATEWNPKNKKDAPPKKKNALVILERVASRSNQNAVSRVINILRSKVHLMFSSSNELPSSEDVERWKKSPETLAASEYGCNLFIQFLKEQTSENEVDFWLDCQKFRSSKMSSRQNEARRIFDEYFAMGSPKKIYIERYLWCVVQAYLVNDPGWRHTFDVAQAYVGLKLAKKSHKKFLEDPLYLDLVELVTSGVNYNKFWHDKLE
What is the function of this protein?
Shown to have a role in viability and embryogenesis.
What are the official names of this protein?
Regulator of G-protein signaling rgs-10.
Protein: ENO_SHESH
Sequence: MSKIINVIGREIMDSRGNPTVEAEVHLEGGFNGMAAAPSGASTGSREALELRDGDKTRYMGKGVLKAVANINGPIRDALMGKDATNQAELDQIMIDLDGTENKDKLGANAILAVSLSAAKAAASFKGLPLYAHIAELNGTAGQYSMPVPMMNILNGGEHADNNVDIQEFMVQPVGAKTFREALQVGAEIFHNLKKVLQEKGLSTSVGDEGGFAPNLASNADALAMIKVAVEKAGYKLGEDVTLALDCAASEFYKDGQYDLTGEGKVFSANGFSDFLKSLTEQYPIASIEDGLDESDWDGWAYQTQIMGDKIQLVGDDLFVTNTKILKRGIDNNIANSILIKFNQIGSLTETLAAIRMAKDAGYTVVISHRSGETEDSTIADLAVATSAGQIKTGSLCRSDRVAKYNQLLRIEEQLGEKAPYRGRSEIKGKA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL36_SALTO
Sequence: MKVKPSVKRICNKCRVIRRHGRVMVICADPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: VANS_ENTFC
Sequence: MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGKLGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKYFDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVMYLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRYNLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFNNILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSSDTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS
What is the function of this protein?
Member of the two-component regulatory system VanS/VanR.  Activates the transcription of vanH, vanA and vanX in response to vancomycin which results in vancomycin resistance.  VanS activates VanR by phosphorylation.
What are the official names of this protein?
Sensor protein VanS, Vancomycin histidine protein kinase, Vancomycin resistance protein VanS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.