PharMolix/UniProtQA huggingface dataset:
Protein: ADEC2_JANSC
Sequence: MTDQPAPTDHLIRAADEVKIRQRLVRVALGHVAGDTRLRVGKLLDVHSRMWLSDQEIILSGRRIAYVGPAGSYPGGVAHEVHEPDLMAVPGFGEVHKHIESSHVTPEWEAALVLPHGNTWTCEASHEFSNVNGPHNLEFWLTARLAGSPQKIFPLPGSAVPPTAYEWGGGHFGYDEQAGFLNESLMVAGLDEVMDWPAVWNPENPSYDRLWGMIEATFEKRGVIEGHAAGIRDMATINAFAAAGLASDHEAWTTEEVLDKLRRGLFMELRPHSLSEMVKGLLEAGLEDWGQFALTTDDRSCSDTLKMGATDHNVRLAISAGLSPEVAIQMVTINPARHMRLTPWVGSLAPGRFADIVLLDDLPSVSIRQVWADGELVAEDGTYLKPIPKIDWPDWATQTVKIDRAMMADDFAIPAKRGRDTMHAALLRPFHWDDDFITMDLPVKDGQVQRDPRRNVTKFAIVDRFSGEGKTSAMFWLGTGPRTSDTALACSMGHDKHNVWAVGSSDAAMAMAVNALRDIQGGWALVREGQLVATVRYEVGGLMTCRPPAELDAEMQALYAEGEKIDWMYEPTVSPRWFPGFPERLAFATLTCAPWRWVLVAPSDRAPDGFVNVATGQTHPVVW
What are the official names of this protein?
Adenine deaminase 2, Adenase 2, Adenine aminase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: ARP3B_HUMAN
Sequence: MAGSLPPCVVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDFFIGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKEFAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKNVVLSGGSTMFRDFGRRLQRDLKRVVDARLRLSEELSGGRIKPKPVEVQVVTHHMQRYAVWFGGSMLASTPEFFQVCHTKKDYEEYGPSICRHNPVFGVMS
What is the function of this protein?
Plays a role in the organization of the actin cytoskeleton.  May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  May decrease the metastatic potential of tumors.
What are the official names of this protein?
Actin-related protein 3B, ARP3-beta, Actin-like protein 3B, Actin-related protein ARP4.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection.
Protein: SYH_CHLPD
Sequence: MSQYQVVKGARDIFPDEIVRWHYVEDVVHRLASLYGYSEIRTPVFEYTELFQRSIGTTTDIVGKEMFSFLPDPQGRSITLRPEMTAGVMRAVLQKNLLSTAPIHKLFYLSELFRKERPQAGRQRQFSQFGAELLGVSSPAAVAEVITFMMQVFETLGIRGLKLRINTLGDSSDRARYREILRAYLAPFYDRLDLASRERFEKNPLRILDSKNPDMQEIIEGAPTLHDSLSHEALEDFEKVRFYLDSRSIAYDIDYRLVRGLDYYCHTAFEVTSPELGAQDAIGGGGRYDGLAKELGSSGDVPASGFAAGMERVLITMEKQGLFAALRPSGPKVYVVAQQHALLDHALQVAYRLRREGISTEVDLAGRSMKAQMRDANRMRACFALFIGEDEVVSGSYALKNLVTADQTAQSIETIIEMLNQYSGAEQGS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSAO_SALTY
Sequence: METLLEIIARREKQLRGKLTVLDQQQQAIITEQQICQTRALAVSTRLKELMGWQGTLSCHLLLDKKQQMAGLFTQAQSFLTQRQQLENQYQQLVSRRSELQKNFNALMKKKEKITMVLSDAYYQS
What are the official names of this protein?
Secretion system apparatus protein SsaO.
Protein: NU1M_DANRE
Sequence: MLDILTSHLINPLAYAVPVLIAVAFLTLVERKVLGYMQLRKGPNVMGPRGLLQSVADGVKLFIKEPIRPSMASPILFLTAPVLALILAMMLWAPMPMPYPVLDLNLGILFIMAISSLAVYSILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSAVIFSGGYTLQTFNTTQEDTWLLLPLWPLAIMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYSNILLMNTHSTVLFLGASFTPDAPELMTISIATKTAMLSILFLWMRASYPRFRYDQLMHLIWKNFLPITLVLVLWHIALPIALAGLPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISPG_ECO81
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: LGT_ACIBS
Sequence: MLTYPNIDPVAIHLGPLQVHWYGLMYLLAFLCAWGLASYRTKQRDGWTSDMVSDLVFYGALGVVLGGRIGYVLFYEFDKFLENPIWLFQVWTGGMSFHGGFLGVMIAMLFWCKKYQKTWFQTLDFIAPCVPTGLMLGRIGNFIGGELYGRAVTDPNYPFGMIFPTDPLHLVRHPSQIYQALCEGLLLFIILWWFSSKPRPRMAVSALFLMGYGVARFVMEFFRQPDADQGFILFGWMTKGQILTVPMLLIGLWMMWYAYQKKIYDWGPQKNS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CMOB_SHEB9
Sequence: MISFSSFYQQIADSNLQHWLETLPSILGKWQRDHKHGNLPKWEKVLNKLHYPAPDQVDFVDSVTVGSGEQLSPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVKQHISPLKNRTVLDVGCGSGYHMWRMLGSGAKRVVGIDPSPLFLCQFEAVKRLAGTHHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLVEYLDPNDITKTVEGYPAPKRATIIAVKNQPNQDLIS
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: DM7A_DROER
Sequence: MLQIASGNREEGQVVELKKTKYLPYLFNLVMPKSFYHSHNRIVVARLYSNVHKHDKQAAEFFEGFQTPCFEVPASMFPGEAPLNKIVFMPPVMLPMGFEAGGVFGPGVLPRRSYPIDLTASGHKGQSPPLFVGLRRLYVQLPSEIESFLDKMGEFPATQDTLVYGMRRSNQLLKEEQAQELMLRNDLSLSMAYNLPAPPTPPSPYPYRHVPVQYNIYTPDLSNVLMMMPHQRKLTVAILSTVNNPHVPSVALATMGDEECPKFELPSDVFPICEGVNRPIFLPRRFLPKGFESGCVFKPGSLSELWFMGYMGRFSPPQPQHNCAITPPLFVGKISRVVLAFDLMKNIQMEYGAAQSSAQSEGSLNAVEPKKPNVPITKGFLVMETEHPTPPSGGYSLQSYQEGSAKGCVVKVEKGETQEMDEAHPTKEESKSEEEGEVQSGSQEEKYLSWFKVDSDIDLIAETMVDMGTAQMSLIDEEALPGVDGACVLNQLREVFEDRNEIRQNIDQLIHDHIYRMNRDRMLALRLPIRTCFRCGLLPCRHF
What are the official names of this protein?
DM7 family protein GG19680.
What is the protein family that this protein belongs to?
Belongs to the DM7 family.
Protein: LTRA_KLEPN
Sequence: MNLNLLPDLALFVQIVDQGSFSAVARQNGITPSAVSRSVSRLEREMGCKLLQRTTRKLRLSDAGETIYQHAQQMLEAARQAMDSAGSRQTVAQGKLTLSVPKAVGRFVIHPLMMAFFHRYPQVDVCLRLEDRPLDFIDDGIDLALRITDTPSPGLHGKPLMPIRHVICATEAYLQQHGTPYTPQDLRAHSCISLGETPADARWKFRREGKTETVQTYGRYAANHTAVRLDAVRQHLGIGSLPLFTAREALANGDIVQVLPEWEFISSYSGDLWLLWAGDKHMPARMRAMIDYLSETVPALNAGSTEPAK
What are the official names of this protein?
Probable HTH-type transcriptional regulator LtrA.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: UVRA_XYLFA
Sequence: MTALIRIRGARTHNLKNLDLDLPRNTLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLSVMEKPDLDQIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARVGQPRCPDHHYPLEAQTVSQMVDHVLTLDPEQRYMLLAPVVRERKGEHTQVFEQLRAQGFVRVRVDGELYEIDVVPTLTLRQKHTIEAVIDRFRPREDIKQRLAESFETALKLGNGMASVQTLDTTTTTPHLFSSKYSCPVCDYSLPELEPRLFSFNAPMGACPACNGLGVTEFFDPAKVVIHPDLSLSAGAVRGWDRRNAYYFQLIASLAKHYTFDIDASWESLPEEIRHTILFGSGDEQINFIYLTEAGGRTKRKHRFEGIVPNLERRYRETESAAVREELAKYVSTRTCPECGGTRLNRAARNVFVADRTLPELTVLPINDALEFFKTLRLPGWRGEIAIKIVKEIGERLGFLVDVGLDYLTLERKADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLTRLRDLGNTVIVVEHDEDAIRQADHILDIGPGAGVHGGEICAQGSLEQIMAAPRSLTGQYLSGRRRIEIPKQRHPPNATKMLHLRGACGNNLKGVNLDIPEGLFTCITGVSGSGKSTLINDTLFTLAANEINGASHPIAPYASVDGLELFDKVVDIDQSPIGRTPRSNPATYTGMFTPLRELFAQVPEARARGYSPGRFSFNVRGGRCEACEGDGLIKVEMHFLPDVYVPCDVCHGKRYNRETLEIRYKGYNINDVLEMTVEDALKLFEAVPAIARKLETLVDVGLSYLKLGQSATTLSGGEAQRVKLSKELSRRDTGRTLYILDEPTTGLHFYDIEALLAVLHKLRDAGNTVIVIEHNLDVIKTADWVIDLGPEGGGRGGEILVAGTPEAVAAHPHSHTGHFLAKLLPPKDVSNCGHRDPGEEVDIAQTVHR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R113A_BOVIN
Sequence: MAEQLSPGKTTDQVCTFLFKKPGRKVAAGRRKRPICNQESGDSSSSSDEGNTVVRPEKKRAVHNPMIQKTRGSGKQKVAYGDLSSEEEEENKSESLGVVYKSTRSAKPVGPEDMGATAVYELDTEKERDAQAIFERSQKIQEELRGQEDDKIYRGINNYQKFMKPKDTSMGNASSGMVRKGPIRAPEHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERELDEGRYGVYEDENYEVGSDEEEIPFKCFICRQTFQNPVVTKCRHYFCESCALQHFRTTPRCYVCDQQTNGVFNPAKELIAKLEKHRAAEGGGASGFPEDPDEDPVPIT
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins.  Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains.  Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents.  Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF113A, RING finger protein 113A, Zinc finger protein 183.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with ASCC2 in nuclear foci after DNA damage by alkylating agents. In the absence of DNA damage, colocalizes with the spliceosome components SNRNP200/BRR2 and PRPF8 in nuclear speckles.
Protein: PYRF_GEOMG
Sequence: MTRDQAREKVIFALDTGEFAHVQYWAETLSDKVGMYKIGKQLFTACGPAAVRMIQKFGGEVFLDLKFHDIPNTVAMASVEAARMGVKLFNLHALGGYEMMAKTVEALDKEFKGGDRAKVLAVTILTSSTEETLKDLGIEHTVPDMVVRLATLARKAGIDGVVASPREIPLIREACGSDFLIVTPGVRPSFAALNDQKRVMTPAEAVKAGSDYLVIGRPIGDAPDPAAAAELILGEIVAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RS19_GILMI
Sequence: MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDLVKLGRHKELAPSDENWFYIRAASTVRHLYLRGGAGVGSMTKIYGGRQRNGVCPAHYSEGSKNVARKVLQALELLKMIEKDPNGGRRLTAQGTRDLDRIAGQVSAASKKIVQ
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: PURA_PEDPA
Sequence: MTATVVIGSQWGDEGKGKIIDFLGQSADVTVRYSGGDNAGHSLVVNDQKLALRLIPSGILAPNSICIIGNGTVINPATLLDEIKELNGVGVNTDHLKISDRAHIVFPYHILQDQQQERDRSKNGEKIGTTNKGIGPAYMDKMQRIGIRAIDLLDNETLEEKIAFNLEQKKRILDEDLWNQLPSLKELTAQYIEYGEILKDYITDTSYLIHTNLNDNKRVLFEGAQGTMLDIDHGTYPFVTSSNPTAGGAATGAGIGVTKIKHVIGVCKSYVSRVGEGPFPTEQINEVGDRIREIAHEYGTVTKRPRRIGWFDGVLMKYVSEVNGLTDLVVNCLDVLSGFKELKICTGYQTDHGVIKYYPASEKELKNSTPIYETLPGWDEDLTQMTTYEELPANAKNYLKKIEEITGVPVSAFSIGPDREQTIVLNDMWSD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_LACP3
Sequence: MIKQAIEKVVNHENLTFEESEAVLDEIMNGEASEVQTASLLTALTAKNPTIDEIAGAAASMRSHALAFPETKDVLEIVGTGGDHANTFNISTTSAIVVAATGTQVAKHGNRAASSKSGAADVLEALGLDINETPAVSYESLQENNLAFLFAQEYHKSMKYVATVRKQLGFRTIFNILGPLANPAHPTHQLLGVYDETLLEPLANVLKKLGVTNAMVVHGRDGLDEMTTADETAVVELQDDHLTKYTVTPEQFGLKRRQRADLVGGTPEANADITRRILAGDHGPQRDIVLLNAGAALHVAHPALSIQAGIDLAAKTIDDGKAFEELNRLLAFSDKRKDVVA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YCF4_CARCL
Sequence: MNWRSKRIWIELITGSRKISNFCWAFILFLGSLGFLLVGISSYLGRNLISLFPPQQILFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGKNRRIFLRFLIKDIQSIRIELKEGIYTRRVLYLEIRGQGAIPLTRTDDNLTPREIEQKAAELAYFLRIPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: OMPW_SALTY
Sequence: MKKFTVAALALTTLLSGSAFAHEAGEFFMRAGPATVRPTEGAGGTLGHLNGFDVSNNTQLGLTFTYMATDNIGVELLAATPFRHKVGTGATGDIATVHLLPPTLMAQWYFGDSSSKVRPYVGVGVNYTTFFDNDFNDNGKNAGLSDLSFKDSWGAAGQVGVDYLINRDWLIGASVWYMDIDTTANYKMGGVQHHDSVRLDPWVFMFSAGYRF
What are the official names of this protein?
Outer membrane protein W.
What is the protein family that this protein belongs to?
Belongs to the OmpW/AlkL family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: FERH_NOSS1
Sequence: MASYQVRLINKKQDIDTTIEIDEETTILDGAEENGIELPFSCHSGSCSSCVGKVVEGEVDQSDQIFLDDEQMGKGFALLCVTYPRSNCTIKTHQEPYLA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.  Donates electrons to the nitrogenase.
What are the official names of this protein?
Ferredoxin, heterocyst.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
Protein: SYGB_STRP3
Sequence: MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDIQTFSTPRRLAVRVSGLAAQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTDAIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVHTLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKERQEMIVEQIKAIEAAQGVQVDIDADLLNEVLNLVEFPTAFMGSFDAKYLDVPEEVLVTSMKNHQRYFVVRDQEGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQKLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIYKFDLLTGMVGEFDELQGIMGEKYARLAGEDAAVATAIREHYLPDAAGGALPETKVGAVLALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYDLSFDSLTYANKADVMNFIRARVDKMMGKAVPKDIREAVLESSTFVVPEMLAAAEALVKASHTENYKPAVESLSRAFNLAEKADASVHVDPSLFENEQENTLFAAIQGLTLAGSAAQQLEQVFVLSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKTIAAFNQLNTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_HELAN
Sequence: MGFVKVVKNKQYFKRYQVKFKRRREGKTDYFARKRLIAQDKNKYNTPKYRLVVRFSNRDITCQVAYSRIEGDKILCAAYAHELPQYGVKVGLTNYAAAYCTGLLLARKLLSQLGLDKLYIGSTEVTGEEFNVKPVEDGPGAFRCYLDVGLMRTTTGARVFGAMKGAVDGGLNILHSTKRFPGFDSESKEFNADVHRQHIFGQHVAEYMRQLAEEDDEAYKRQFSQYIKLGLNADAIEGLYKKAHEAIRANPARKTVAKKAHPKKRWTEKKLTREQRQGKVAAAKAEWLKKIEAGEVE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPA_LIMF3
Sequence: MTELTNADLLTAIVTPFTDEGTIDYPALDQLTEHLLQAGNNGFVVGGTTGETPTLSHDEKIELYTHFGRLIAGRVPVIAGTGSNNTAETIAFTNEVAQIEGIDYALVVVPPYNKPNQRGMLAHFTAVADAVELPLIIYNIPGRTGVKMETSTVLTLAEHPNIAGIKQCASLEEFQTLVENRPAGFAVYTGEDAQALTTKVLGGDGVISVAAHNYAPQMRAMYDALSAGNYQVAAKLQRWLTPRMAALFMFPSPSPVKAVLAAQGLATDHCRLPICDLTAEEKEQLATALGLPSDALAGQLPTDLGEGLTND
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_XANOP
Sequence: MASDFLPVRRALLSVSDKTGLIDLARALVARNVELLSTGGTAKAIREAGLPVKDVAELTGFPEMMDGRVKTLHPLVHGGLLGRAGIDEAVMAEHGIAPIDLLVLNLYPFESVTVKTDCTLADAVENIDIGGPAMLRSAAKNFARVAVATDPAQYADLLAELEANNGQLSAAKRFALSVAAFNRVAQYDAAISNYLSAVADSAETVPTRNPFPAQINSNFVKVMDLRYGENPHQSGAFYRDLYPVPGTLATFQQLQGKELSYNNLADADAAWECVRQFDAPACVIVKHANPCGVAVGAGCGDAYELAYATDPTSAFGGILAFNKTLDAATAKAILDRQFVEVLIAPDYDAGALEYATKKANVRVLKIPHGNGLNNYDTKRIGSGLLMQSADNRGMSLGELSVVTQRAPSEAELGDLLFAWRVAKYVKSNAIVYAKDSRTIGVGAGQMSRVVSAKIAALKAEEAKLTVAGSVMASDAFFPFRDGIDAAASAGIQAVIQPGGSMRDGEVIAAADEHGIAMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ECPA_ECOLX
Sequence: MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSIISGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Major subunit of the fimbria (By similarity).
What are the official names of this protein?
Common pilus major fimbrillin subunit EcpA, MatB fimbrillin.
What is the protein family that this protein belongs to?
Belongs to the EcpA/MatB fimbrillin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: CQ055_HUMAN
Sequence: MPRSLKRAQLRSLLPRPPAVSHTQPWYRAAHPTTSPTAASRDVHPASGAVPGPWLVEGTAVREGPQLQDAVPQRPTRPSKALWPAQMSAAPAIRLGQMVPGDTRGLWGPQGTLLTWTYRGGQGGRWTRRAEGPREGTFAEQRPHFQSSGAQQESRLAMGPPPLGLGDAAGDGRGQTGQEKGRAEGRQARKSACKCPRKGPNPGPWTRAAAWWGRLEGAKASAKGEQVRDPGGHLWEQGHVSPCARFNQGHSCGSPKVSHTTWVS
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00482.
Protein: TYPH_SHEDO
Sequence: MFLAQEIIRKKRNGQALTAAEIQFFVNGITTNSVSEGQIAAFGMAVYFNDMNMDERIALTIGMRDSGTVLNWDSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAILGYQTEPSSELFRKVVKEAGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLAAGLDALVMDVKVGSGAFMPSYAASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVVEAINFLTGEYRNPRLYEVTMGLCAEMLVLGGIAQNEIEARTKLNTVLDNGKAAEVFGKMIAGLGGPTDFIEAYDKYLPQAKIIRPVFSDAQGYAHSMDTRELGLAVVTLGGGRRKPGDKLDYSVGLTQVCALGEQISTDKPIAMIHAQTEDDFLEAELAVKNAIKIQSSMPEKMPEIYRYIRAADL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: SAT6_STACB
Sequence: MPQDPNTTLQMSSSKPSLSDLSVSADPVLGKADNQVRDSLALPSIEGGEEGVMRPLAWLFGLCAIQQASGATLLRNDVSTVEPLPPTQDPWYRAPPGFEKKQPGDVLRIRQAPGNLTTVVSNSSAAFHILFRTTNARSEPAWAVTTLFLPKKLYRAPSRNAALLSFQLADNSANPDSAPSLGLYWRLAQDNPMLGLRSDTSFISNLLSEGWLVNIPDQSGPEAAFGASRQAGHATIDAIRAIQHLCSLTGATGINAAIWGYSGGTFATGAAAELMPTYAPNINIVGAVLGGMVTDVSGGFDSLNRSPIAATIIATLLGVTAQFPEERAYLESRLVPETRDEFMSVLDINVFDALVHFAGRDIYAFFIDGAADIEAPILQNLFEAQSRIGFGDIPPMPMFIYKAIADEVVPIGPTDVTVQRWCDGGADITYERNTVGGHIAEIENGKPRAIQWLWSIFDESYSAQSPECRIRDVTVEVPVQVVGRV
What is the function of this protein?
Probable trichothecene esterase; part of the satratoxin SC1 cluster involved in the biosynthesis of satratoxins, trichothecene mycotoxins that are associated with human food poisonings (PubMed:25015739).  Satratoxins are suggested to be made by products of multiple gene clusters (SC1, SC2 and SC3) that encode 21 proteins in all, including polyketide synthases, acetyltransferases, and other enzymes expected to modify the trichothecene skeleton (PubMed:25015739).  SC1 encodes 10 proteins, SAT1 to SAT10 (PubMed:25015739).  The largest are SAT8, which encodes a putative polyketide synthase (PKS) with a conventional non-reducing architecture, and SAT10, a putative protein containing four ankyrin repeats and thus may be involved in protein scaffolding (PubMed:25015739).  The putative short-chain reductase SAT3 may assist the PKS in some capacity (PubMed:25015739).  SAT6 contains a secretory lipase domain and acts probably as a trichothecene esterase (PubMed:25015739).  SAT5 encodes a putative acetyltransferase, and so, with SAT6, may affect endogenous protection from toxicity (PubMed:25015739).  The probable transcription factor SAT9 may regulate the expression of the SC1 cluster (PubMed:25015739).  SC2 encodes proteins SAT11 to SAT16, the largest of which encodes the putative reducing PKS SAT13 (PubMed:25015739).  SAT11 is a cytochrome P450 monooxygenase, while SAT14 and SAT16 are probable acetyltransferases (PubMed:25015739).  The SC2 cluster may be regulated by the transcription factor SAT15 (PubMed:25015739).  SC3 is a small cluster that encodes 5 proteins, SAT17 to SAT21 (PubMed:25015739).  SAT21 is a putative MFS-type transporter which may have a role in exporting secondary metabolites (PubMed:25015739).  The four other proteins putatively encoded in SC3 include the taurine hydroxylase-like protein SAT17, the O-methyltransferase SAT18, the acetyltransferase SAT19, and the Cys6-type zinc finger SAT20, the latter being probably involved in regulation of SC3 expression (PubMed:25015739).
What are the official names of this protein?
Probable trichothecene esterase SAT6, Satratoxin biosynthesis SC1 cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.