PharMolix/UniProtQA huggingface dataset:
Protein: DN7_SULTO
Sequence: MVTVKFKYKGEEKEVDISKIKKVWRVGKMISFTYDDNGKTGRGAVSEKDAPKELLQMLEKSGKK
What is the function of this protein?
Can constrain negative DNA supercoils.  May be involved in maintaining the integrity of the genome at high temperature.
What are the official names of this protein?
DNA-binding protein 7, Sto7.
What is the protein family that this protein belongs to?
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSLP_LOTGI
Sequence: MKFGVGFLLSCLVALNTVQNMLALSCLPCDFDTLKCSPLPDDDDCFPAYTPCGCCPQCAGEEDDFCDNFTVRCHPDLVCVNATGFEKKFVYWYEFDFKGTCQESELETEYEYEYEENETKK
What are the official names of this protein?
Perlustrin-like protein.
Protein: IHFB_ALIF1
Sequence: MTKSELIEQLCSKKPQLSAKQVEDTVKEILEQMATTLEGGDRIEIRGFGSFSLHYREPRLGRNPKTGDKVELDGKFVPHFKPGKELRERVNYS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: GCSPA_DICTD
Sequence: MAYFPHTPQEIREMLNTIGVDSIEELFSEIPEEIRQKAKENFKLSASPSEIDLLEEIKQISKKNIGKDYISFLGGGAYRHYIPSFVKLVSLFPTFYTSYTPYQPEISQGVLQSIFEYQSLICDLTGMEVANASLYEAGSGIAEAALMSVRITGKKEVIVSSGLNPEYISVLKTYLQVQNIDLKILPLDENGETDITALERTISPSTSGVILQNPNFFGVIETKLKEMETLIHKNNALFILSIYPISLGILKPPSEYNVDIVVGEGQSLGIPLGFGGPYLGILATKKEFIRQIPGRIVGETIDLEGERGFVNTLQTREQHIRRAKATSNICTNEALSAISAAVYMALLGKKGIKKIAEVCFSRAHYLKDRLQKKLGIDFIYPNSYFFNEFVIKTPENSKVFLKKLEERKILGGIPLSKFYKEREKEILIAVTERNSIEEIDYYVKSLKEVLKKD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: LONP2_DEBHA
Sequence: MARYKPNQQNHTDPKQQVVLPTYKLDSNLVLLPGIIYNVTFSRFKAATLLSRFKSQVSNVSLITNLLNEYDFDSKQEEKDDVESKYMPPPISSDAVTGIKQFYQYEQQFKGKNDDSSKVEAEPQSEFDWLVLAINPNLEKIKEPQTSSDDEYENIVTIARVIGMVDDTSNIKLTLQALTRGIKHNKVKPTQTNEVLIDIDWNSNIDDVASKYDVLNSKVLKLFRSIDGFIVDYRQALTVAASLAKKGKQSKDLKQKGDLLTLNPLANSLYLHLAASKDFTKAYISLQKLFGTFNSSSNTKIDNKTFLRLIDLTCAIIPFPNHEKLKLLNKFNSIDRINEVNRMLESMIQVFYNLKKNNKIINHWFYNEATNIQRANVVASQLKSIRLILEGMTNKPDKDIKTNQSPPRQLVRRGNNNKPAKSPMSDDGNESNDEYDDDEDDDDDEDELKAITSFIKGKLPNISTLSSDTKRLIVKDFKRIKSSPPGNSDFHVIRNYLEIVADIPWDRYVTRFKSNKDIDLEFAKKQLDSDHYGLQHVKTRLIQYLVVLKLLGINAEKEFEKIESENSKKSKKNESSSGSMGKNDKQRSEKTFTRSDDSIVIANNDETSIAHETARNKNKKSKSLTTIEKSSLNKSLMVSKNNKSPIIMLVGPPGTGKTSLAKSIAKSLGRNFQRVSLGGIKDESEIRGHRRTYVGAMPGVIIQSLRKSRSMNPVILLDEIDKIIGGNNGVNKFNGDPSAALLEVLDPEQNTSFIDHYLGFPVDLSQVMFICTANEASNLSRPLLDRLEMIEVGAYDYDEKLVIGERYLLPRQIKRNGIPNADLIDVDKSVMQKVILDYTREAGVRNFERSLGRICRFKAVEYSQSLEKLSEYQPKVEIEDLPKYLGLPFANLSTELFESPIESAKCGVVNGLSYNSDGSGSVLVFESIGFNHEGKSGSSSLNMTGRLGDVLMESAKIGLTFIKSIIYKNLLNLSDRNLSENLIDKINNMEIHLHVPSGSIQKDGPSAGITVALSFLSLILEKPVPLDVAMTGEITLRGLVLPIGGIKEKILGAHLNGIKRVIVPRENRKDLIEEYCRSTNDFNQLNDLLLDNENKYNFKRCEPEKFWFDKYGITIHYAREFWDVIKAVWGDALLVKVEQARMVEYHL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: MSH3_ASPNC
Sequence: MPLPSSQNSSSPGVKRKQSTLASFFTKKPQTAQQASVNVVEEKSPAATFDKADNQERAAKKDKALTDDEEDDIVAPAPKRVRTNGLYPASREEIPNSTSTTERPPALTSSQRTERFKFSSSPAVNTGVEGSQAAVELEAGQRQKEREELHHKFVRKLGGADCLIGIGRNAISEATPEEGAEPEDEEEAAPPPPAKGKAAAKKGGSKLTPMEKQVIDIKRKHMDTVLVVEVGYKFRFFGEDARVAAKELSIVCIPGKLRFDEHPSEASHLDRFASASIPVHRLHVHVKRLVAAGHKVGVVRQIETAALKAAGDNRNAPFVRKLTNLYTKGTYIDDAEGLGGPMPAASGGASPATGYLLCITETNAKGWGNDEKVQVGIVAVQPATGDIVYDDFEDGFMRSEIETRLLHIAPCELLIVGELSKATEKLVQHLSGSKLNVFGDKTRVERVLKSKTAAAESHSHVSSFYAGKMKTASAADDAQASSLLQKVLNLPEQVTICLSSMIEHMKEYGLEYVFELTKYFQHFSSRSHMLLNGNTLMSLEIYQNQTDHTTKGSLFWTLDRTQTRFGQRMLRKWVGRPLLDKSRLEERVNAVEELKNPEKTVMVERLKGLLGKVKSDLEKSLIRIYYGKCTRPELLTVLQTMQMIAQEFSDVKSPADTGFASTAINEAITCLPTILEDVVAFLDKINMHAAKSDDKYAFFREAEETEDISDQKLGIASVEHELEEHRSVAGQKLGKKTVEYKSVAGIDYLIEVENSSASIKRVPASWVKVSGTKKVSRFHTPEVIQLMRQRDQHKEALAAACDQAFISLLADIATKYQPFRDSVQALATLDCLIALATIASQPGYVKPEYTDHTCIQVDQGRHPMVEQLLLDSYVPNDIDLDSDKTRALLVTGPNMGGKSSYVRQVALIAIMGQIGSYVPAQSAKLGMLDAVFTRMGAFDNMLAGESTFMVELSETADILKQATPRSLVILDELGRGTSTHDGVAIAQAVLDYMVRSIRSLTLFITHYQHLSSMVHSFADQELRNVHMRFTESGTGTDEEITFLYEVGEGVAHRSYGLNVARLANLPGALLDQARQKSKELEEKIRRRKLAGLVTAVGEVIEGSKDENMIERLISSAEQL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  Msh3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein msh3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPBD_PARDP
Sequence: MKIAEIHVYAHDLPVKDGPYTIASSTVWSLQTTLVKIVADSGLAGWGETCPVGPTYAPSHALGARAALAEMAPGLIGANPLQPLVLRRRMDGLLCGHNYAKAAIDIAAYDLMGKHYGVRVADLLGGVAAERVPSYYATGIGQPDEIARIAAEKVAEGFPRLQIKIGGRPVEIDIETVRKVWERIRGTGTRLAVDGNRSLPSRDALRLSRECPEIPFVLEQPCNTLEEIAAIRGRVQHGIYLDESGEDLSTVIRAAGQGLCDGFGMKLTRIGGLQQMAAFRDICEARALPHSCDDAWGGDIIAAACTHIGATVQPRLNEGVWVAQPYIAQPYDEENGIRIAGGHIDLPKGPGLGITPDESLFGPPVASFS
What is the function of this protein?
Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B).  Is involved in a catabolic pathway that degrades tHyp-B to alpha-ketoglutarate.  This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant.  Can also catalyze the racemization of L-proline betaine.
What are the official names of this protein?
4-hydroxyproline betaine 2-epimerase, Hyp-B 2-epimerase, (4R)-4-hydroxyproline betaine 2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: CHD2_HUMAN
Sequence: MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT
What is the function of this protein?
DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3. 3.  Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3. 3 prior to the onset of myogenic gene expression, promoting their expression (By similarity).
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 2, CHD-2, ATP-dependent helicase CHD2.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Note=Binds to myogenic gene promoters.
Protein: RS3_KINRD
Sequence: MGQKVNPFGFRLGITTDHRSRWFADSTKTGQRYADYVKEDVAIRRLMSKGMERAGISKVEIERTRDRVRVDIHTARPGIVIGRRGAEADRIRTELEKLTGKQVQLNILEVKNPEVDAQLVAQGVAEQLASRVSFRRAMRKGMQTTMRSGAKGIRVQCAGRLGGAEMSRSEFYREGRVPLHTLRANIDYGFYEARTTFGRIGVKVWIYHGDITSRELAQSQAAAPRAPRRNERGDRPDRGARRTRPAQDTTAPVAEAVATGSAPTGTAATEPVIGKGSNGTEA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ACCA_STRT1
Sequence: MSDVARILKEARDQGRLTALDFAKEIFDDFIELHGDRNFRDDGAVIGGIGRLNGQAVTVVGIQKGKNLQDNLNRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADKVWMLENTIYSILSPEGFATILWKDGSRSEEAAELMKITSGELLNMGIVDKVIPERGYFTSEIIEAIKTAIVDELAELSQLSTEDLLEARYQRFRRY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ACIBC
Sequence: MFISFEGTEGVGKTTLIRKIHQHFEEQGKQVVLTREPGGTPLAEQIRSMLLAVNHDENMSHDTELLLIYAARAQHLQQVILPALESNKIVLSDRFTDASFAYQCSGRGLSQDKLQLLNQNFVSRMPEVTFWLDAPIELGMNRARERGALDRFEQEKLSFFTKVREGYETLWKAEPERIKRLDATQSPDQVFEQALQYLA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DNAJ1_CUTAK
Sequence: MSNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKRAVFDRGGDPNARMGGFGEGGFSSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDALVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSEPVTCDTCQGRGEVITVQRSFLGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGEVGPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFAEDTKTVTVEVPAGTQSGTRIVVSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQLAEAREETNASASVEKSGGRGMFSRIKEAFGG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 1.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVA86_HUMAN
Sequence: MLLLLVPAFQVIFTLGGTRAQSVTQLDSQVPVFEEAPVELRCNYSSSVSVYLFWYVQYPNQGLQLLLKYLSGSTLVESINGFEAEFNKSQTSFHLRKPSVHISDTAEYFCAVS
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 8-6.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RK20_BRADI
Sequence: MTRVPRGYIARRRRTKMRSFASNFRGAHLRLNRMITQQVKRAFVSSHRDRGRQKRDFRRLWITRINAATRIFKVFDSYSKLIHNLYKKKLILNRKMLAQVAVSNPNNLYTISKKIKIIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUA_PSET1
Sequence: MRVALGVEYNGARYSGWQRQSHVNSVQQEVETALSRICNHPVAIVCAGRTDAGVHGTGQVVHFDTDAPRDMVAFTLGMNTLLPKDIAIRFAQPVADDFHARFSATARRYRYVIYNNPLRGAVLNEGVTHFHHTLDETKMQEACQYLIGKYDFTSFRAIHCQANTAIRTIQHLSVQRQGSYVIIDIKANAFLHHMVRNITGCLMDIGLHKQQPVWLKELLDLKERAKASATAKAAGLYLVDVDYPEQFNIPKTPLGPLFLPDISI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: VCX3_HUMAN
Sequence: MSPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEELPSV
What is the function of this protein?
May mediate a process in spermatogenesis or may play a role in sex ratio distortion.
What are the official names of this protein?
Variable charge X-linked protein 3, Variable charge protein on X with eight repeats, VCX-8r, Variably charged protein X-A, VCX-A.
What is the protein family that this protein belongs to?
Belongs to the VCX/VCY family.
Protein: PSRP5_ARATH
Sequence: MALLCFNSLPSLSSLSSSSSSRLLQSPSFASPVLSLKPNAVESKNRVSLSAYSLNSSHGRIVVKAAASGVDGAEPESKEEPKTVVAAVPVDKLPLESKEAKEKLLLELRLKMKLAKKIRLRRKRLVRKRKMRKKGRWPPSKMKKNKNV
What are the official names of this protein?
50S ribosomal protein 5, chloroplastic, Plastid-specific 50S ribosomal protein 5, PSRP-5.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cL37 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUTE_ECO81
Sequence: MNEAVSPGALSTLFTDARTHNGWREPPVSDETLREIYAQMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: CHI1_CANAL
Sequence: MILNLIILLAISIVASASNIAAYWGQNAGGDQQTLGDYCSSSPASIIILSFLDGFPNLSLNFANQCSGTFSSGLAHCSQIGSDIKSCQQQGKTILLSLGGATGNYGFSSDSEAVQFAGTLWNKFGGGKDSERPFDDAIVDGFDFDIENKDQTGYAALATQLRKYFSTGTKSYYLSAAPQCPYPDESVGDLMSQVDLDFAFIQFYNNYCSLNQQFNWNSWSNYARGKSIKLYLGLPGSSSSAGSGFVGLSTVQRVVASIKGDSSFGGISIWDISSAENGGYLNQLHQALSGSGSPAAPSNSYQPNTPLTRTYGGSTATASAYISVGFTAGATHGSTTTNDLLAWIDSLFGSSQSSVQQYATPVQSVTATPQPVAATTTSAPKPTASAFNWFGWFDGTTTSTTLQTVYSTVPADQTVYVTLTTTVGSQMLQSLFDKRDVIAEAKSTNLQICWLLFIPLLALICS
What is the function of this protein?
Chitinase involved in the remodeling of chitin in the fungal cell wall.  Plays a role in cell separation.
What are the official names of this protein?
Chitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUS79_ASPNC
Sequence: MHHHPITLLSLLLGAAQSIAAHPTAHDERRSSSSIGVSASVPDDAALPVLHPFVSFSIEFAFFPDFAGNLSHPNLFSNQLLDNLADLQGAKPYIRVGGNTQDFALYDPKLRAATNATYITSISTDYPLILSFGPAFFESYFTWPGTKFIHGFNLGKNSSSDIELMLESVPLACKALEGGKLAYWELGNEPDLYKTSAQGIRRPASWTEQDYVDEWLNKTARIEKRLVEACPELAESKYIAPSFAGVTNSLNPVVTWEKGLDKSRNIALNSEHNYIGGATQPGVTLQNTLMNHTKTVESVAQQVNVSRILSKDNLTPGIPYILGETNSLYNEGAPGLSNSFGAALWGVDFNLYCASQNIRRTHMHQGSNYNYISWQPVGTNRTTIGTKAPYYGNAMVAAMLHGGDDVRIVNLPLAADTEAAYAAYVNETLVRVAVINLVEFNYTSTDSTAEKVESRPSAKYTFQLPSSESVYAGSVSVQRLMANGSNAITGITWDGWSYNYELAQGKPVRLQNVTTGEAISVGDDGVVEIEIPYSSAAILSL
What is the function of this protein?
Beta-glucuronidase that hydrolyzes beta-glucuronosyl and 4-O-methyl-beta-glucuronosyl residues of arabinogalactan-protein.  Hydrolyzed heparan sulfate only very weakly.  Has no activity on xylan from birchwood.  Able to catalyze the transglycosylation of glucuronic acid (GlcA) residues from p-nitrophenyl-beta-glucuronic acid (PNP beta-GlcA) to various monosaccharide acceptors such as glucose, galactose and xylose.
What are the official names of this protein?
Beta-glucuronidase, GlcAase, Beta-D-glucuronoside glucuronosohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 79 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MENH_ECO7I
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEVFADYSRLYVDLPGHGGSAAISVDGFDDVTGLLCKTLVSYNIPDFWLVGYSLGGRVAMMAACQGLAGLCGVVVEGGHPGLQNAEQRTERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDEQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAAECYVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: RUVB_BRASO
Sequence: MKPPARMVSPERRSDDVGDTALRPQQLSEFVGQQQARANLSIFIEAARKRGEALDHVLFVGPPGLGKTTLAQIVARELGVGFRATSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEVLYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVGATTRAGLLTNPLRDRFGIPIRLNFYTVEELEGIVTRGARVLGIGMTPDGANEIARRARGTPRIAGRLLRRVRDFASAADASAIDRAIADHALSALEVDAAGLDAMDRRYLSTIALNYGGGPVGVETMAAALSEPRDAIEDIIEPYLIQCGYLQRTPRGRLLTSHAFKHLGMAEPANRDPSQIGLFGNDDD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.