PharMolix/UniProtQA huggingface dataset:
Protein: DPEP1_PIG
Sequence: MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSSLAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVGFGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHAQVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
What is the function of this protein?
Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
What are the official names of this protein?
Dipeptidase 1, Beta-lactamase, Microsomal dipeptidase, Renal dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor. Cell membrane; Lipid-anchor, GPI-anchor. Note=Brush border membrane.
Protein: ACKA_GEMAT
Sequence: MNILVLNAGSATLKFQVVVTDAQRIAADQDEKLIRGQIERIGGESVITLRLPDGSSRKRTAALRDLRAAVDWLVGFVTSAESGTGLSARADLHAVGHRVVHGGEQFRNSVRVDDGVLRGIEETIELAPLHNPHNLRGIEAARAALGDGVPQVAVFDTAFHQTLPEHAYLYAIPYPLYRRHKVRRYGFHGTSHRSIAYRFRKLTGRAKADVRIVTLHLGNGCSACAIKDGQSIDTSMGFTPLEGLVMGTRAGDIDAALLDYIGAKEGLSPPQVEAMLNSQSGLLGISGLTNDMRDLLAEANELRDRRARLAIEMFCYRARKYVGSYLAAMGGADAVVFAGGVGENAPEVRALICEGLQWAGLHIDADRNQALVGGQEGRFSTEGAALEAWVVPTDEELLIARDTYRAVGDGAV
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQA1_CAEEL
Sequence: MSLTNSGSDNLIILPTLPEGFAYCLETSQSAPSEPATNFVFRLNIFATRTTGSDVKVEDGSSENMVQVPGIAPNVEAETPIVNGTVVKHESSVASVDERVESGSGEDMAEAPGILPSVKIEAPIANGVVLKNEPMIRVQNNPIPDESIDVKTFVLCDFKTRDRDKYSERTASLL
What are the official names of this protein?
Uncharacterized protein C28F5.1.
Protein: CYAY_CUPNH
Sequence: MPPLSESEFLALATQELDRIEATVEAAADAADADIEISRTGNVMELEFENGTKIIINSQAPMQELWVAARAGGFHFRRDGERWIDTRNGGELYAALSGYVSEQAGAALTLG
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: BTR_BORPE
Sequence: MQRRVPLSPDAAHCSSCMLGHVCVPVGMPANEVEKLDELVKERVRVERGKTLYELDDPLDAVYGVRFGSLKTQLEDSSGQLQITGFHLPGEIVGLDGMIESKHVSSAVALEDSEVCVIRLPEIDRVSTQLPSLQQQFRRLMSREITRSHQMLATVGAMRSEQRLAAFLLNLSQRYAALGYSSTEFVLRMSREEIGNYLGLTLETVSRLFSRFGREGLIRINQREVRLIDLPGLKQLIGQESC
What is the function of this protein?
May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment.
What are the official names of this protein?
Transcriptional regulatory protein btr.
Protein: RL13A_CANLF
Sequence: MAEGQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLNYLAFLRKRMNTNPSRGPYDFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV
What is the function of this protein?
Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions.  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.  In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex.  Involved in methylation of rRNA.
What are the official names of this protein?
60S ribosomal protein L13a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_CLAM3
Sequence: MTAATAPDGRRMLRLEVRNAETPIERKPGWIKTTARMGPEYQALQQLVKTEDLHTVCQEAACPNIYECWEDREATFLIGGSQCTRRCDFCQIDTGKPADYDTDEPRRVADSVRRMGLRYATVTGVARDDLPDEGAWLHAETVRRIHADNPGTGVEILATDFSGNPDLLAEVFSSRPEVFAHNVETVPRIFKRIRPAFRYERSLDVITQARDAGLITKSNLILGMGETRDEVSEALVDLHDAGCDIITVTQYLRPSPRHLPVARWVRPEEFVEIKAEAEAIGFLGVLAGPLVRSSYRAGRLYAQSMRAKGRELPEGLAHLADPANGFAQAVG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF22_MOUSE
Sequence: MRSRLWLGLAWLLLARAPGAPGGYPHLEGDVRWRRLFSSTHFFLRVDLGGRVQGTRWRHGQDSIVEIRSVRVGTVVIKAVYSGFYVAMNRRGRLYGSRVYSVDCRFRERIEENGYNTYASRRWRHRGRPMFLALDSQGIPRQGRRTRRHQLSTHFLPVLVSS
What is the function of this protein?
Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis.  Can stimulate cell proliferation (in vitro).  May be involved in hair development.
What are the official names of this protein?
Fibroblast growth factor 22, FGF-22.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSA_LEPIN
Sequence: MGIEVKNLVKRFGNFTAIDDLSLDVPSGELVALLGPSGSGKTTLLRIIAGLEDADKGQVIFEGREVGKKNAKDRGVGFVFQHYALFRHMTIFENIAFGLEVRKRSERPSKDTIRDKVMSLLKLVQLENFYNRYPSELSGGQRQRIALARALAIEPRFLLLDEPFGALDAKVRKELRNWLRRLHDEIHITSVFVTHDQEEALEVSDKVVILRSGKIEQVGTPDEVYNHPKNSFVFHFLGDVNLFHGRVQGGQTQLGEIKVDTPEHSEIENASAVGYVRPYDVEILREPIEAQTIPAEIQYIHSTGRNVKIDLKRLDTGTILESQLNSSEFQSLNLLPGETVHIRFKKIKVYVEDYTI
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PDIA6_HUMAN
Sequence: MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
What is the function of this protein?
May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115).  Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390).  May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390).  Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).
What are the official names of this protein?
Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, ER protein 5, ERp5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
Protein: GATB_STRZT
Sequence: MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSFPGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNSFSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPDLPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVALGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVFVHLAKNGGGAREYVEKAGMVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVALKLLAQELAKLKEN
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: NOP14_YARLI
Sequence: MAKTSQLKRLKETLKKNDLTGQTNVKGNKKKMNSGKNRQDRDKVLSDIRQQFNPFDVKVARKKHDIGGRTVRGSVGRPGLSKLSGEEARMEARKLELQNKGRVGGVFDRRFGEGDSNMNPEEKMLERFTRERQLRSMGGGRNKSIFALDDDDDDADADMMLTHSGQALDFKDDFDQGDLGIEAEEDEEMAAILANRRKLAEERGMGAMGVNLEEMDGVDMEEAGTGRKKSKEEVMKEIIAKSKFHKAERQAARDKDQAIIEEMNDEDTMNALIRELGSIKAKKVVTALDQKEKEYDQNFRNMILDRRAKPQDRTKTDEELAKEEAEKLKKLEDERQARMRGEVAIDQGEGDDLDGNVAFDFENSEEEGEDDEDEAEDDDDEDVEIHEVDEDEDESGDKSGDESGEEETTKSEPASKSSSSTLAYTFPIPKSHKMFLETTSAYPLDQLPTIIDRINVLHHASLKEGNKERLAKFACVLIDHLMYLADEEEEDDFECLSEVVAKVHTLAETHSPTMAAHIRKKLEAHQADTTVTAGHLMLWTLIGMIFSTSDHFHLVVTPAVLVMTRFLSLSTFDSIPKCIAGLYTAQLLIQYQRIAKRFIPEIAVFLGRLIAALEGTETSLPMASLFKIAPIKGFTPGKASHKSTDKTISMRSANRSILSKKEVATLSQELHNQAVFSVSKLMDTYKDISAFPETFEFCENIPELADKYSRITKFKLADRKPLTLHKHRPLAIKTMAPKFEENFNVDKKSYNPDMALQETQKLRAELKKEKKSALREIRKDAAFEAREKIRERREKDDAYHEKMARLVRSVQTEEGAEKNAYERERASRKRKR
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
What are the official names of this protein?
Probable nucleolar complex protein 14.
What is the protein family that this protein belongs to?
Belongs to the NOP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MLXIP_MOUSE
Sequence: MAADVFMCSPRRPRSRGRSVLLKPQVPEDDDDSDTDEPSPPPPSGVATSARAHASAAPLPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRRNPVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDEDLSSLAQDDDMLYWHKHGDGWKTPVPMEEDSLLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPPPSSLPAADPSSPPSQGNILPNTALPPASLPNSLITSSAAPSLDPTEGQGCERTSQTVDPFIQPADFGPSEPPLSVPQPFLPVFTMTLLSPGPAPAPVPTALPLVPSPAPTLNPPTPPAFLQPQKFAGVSKSTPVITHTASATLTHDASATTFSQNQGLVITAHHPTPSSSPCALALSPVPQPPAVGPPQPHLTFIHPKPVSLTGVRHKQPPKIVPAPKPEPVSLVLKNACIAPAAFSGQPQKVIMTSAPLKREGILASTVSPSNVVIASAAITRASGVTEFLSHSTSSQPSPVSRLFSPSTVQDSLVKGEQVSLHGGSPQVPATGSSRDCPNSGQASPCPSEQSPSPQSPQNNCSGKSTDPKNVAALKNRQKHISAEQKRRFNIRMGFNTLNSLISNNSKQTSHAITLQKTMEYITKLQQERMQMQEEARRLREEIEELNTTIISCQQLLPATGVPVNCRQLDHMRDMFDEYVKSRTLQNWKFWIFSMIIKPLFESFKGMVSTSSLEEFHRTALSWLDQHCSLPVLRPMVLSTLRQLSTTTSILTDPSQLPEQASEAVTRMGKRSGES
What is the function of this protein?
Binds DNA as a heterodimer with MLX and activates transcription.  Binds to the canonical E box sequence 5'-CACGTG-3'.  Plays a role in transcriptional activation of glycolytic target genes.  Involved in glucose-responsive gene regulation.
What are the official names of this protein?
MLX-interacting protein, Transcriptional activator MondoA.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion outer membrane. Note=Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus.
Protein: ARCD_PSEPU
Sequence: GALVAAYGLYDGFLTL
What is the function of this protein?
Catalyzes electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway.
What are the official names of this protein?
Arginine/ornithine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTHR_BOVIN
Sequence: MVNEPRGNGSPGPRWEGSSSGSESSRTSSRCSTPGLDPERCERLREKMKRKMDSGDKWFSLEFFPPRTAQGAVNLISRFDRMGAGGPLFVDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITGHLNKAKQLGLKNILALRGDPIGDQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPEGESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPRRPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFQVFAHHLSGEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDNCLWQVVEDTFELLSRPPQDKRETEAL
What is the function of this protein?
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine.  Represents a key regulatory connection between the folate and methionine cycles.
What are the official names of this protein?
Methylenetetrahydrofolate reductase (NADPH).
What is the protein family that this protein belongs to?
Belongs to the methylenetetrahydrofolate reductase family.
Protein: LHCA3_ARATH
Sequence: MAAQALVSSSLTSSVQTARQIFGSKPVASASQKKSSFVVKAAATPPVKQGANRPLWFASSQSLSYLDGSLPGDYGFDPLGLSDPEGTGGFIEPRWLAYGEIINGRFAMLGAAGAIAPEILGKAGLIPAETALPWFQTGVIPPAGTYTYWADNYTLFVLEMALMGFAEHRRLQDWYNPGSMGKQYFLGLEKGLAGSGNPAYPGGPFFNPLGFGKDEKSLKELKLKEVKNGRLAMLAILGYFIQGLVTGVGPYQNLLDHLADPVNNNVLTSLKFH
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated, here photosystem I.
What are the official names of this protein?
Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic, Lhca3*1, LHCI type III LHCA3.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YPDC_ECOLI
Sequence: MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPARAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSLLHLCRSVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YpdC.
Protein: GNTP_ECOLI
Sequence: MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGMDLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQLSVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQPGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVDMNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSHGNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLATAAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA
What is the function of this protein?
High-affinity gluconate transporter with fairly broad specificity, including low affinity for glucuronate, several disaccharides, and some hexoses, but not glucose.
What are the official names of this protein?
High-affinity gluconate transporter, Gluconate permease 3, Gnt-III system.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFGM_VANPO
Sequence: MVLLRGVGLLRSSNVTSGGAAATASRGGNLFKCLMNAKRPDGMLVNRRGFHGSMVYKAAMSEEEASELSDVTKQLTGADLQAASKLRNIGISAHIDSGKTTFTERVLYYTGRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATYCSWNKDQKDYHFNLIDTPGHIDFTIEVERALRVLDGAVLIVCAVSGVQSQTVTVDRQMRRYNVPRITFINKMDRMGSNPFKAIEQINSKLQISAAALQVPIGSESNLRGVVDIINRVAYYNKGDQGEIIDKAEVPEDLKDLVEEKRALLIEKLADVDDEIAELFLEEQEPTVEQIKSAIRRATIARKFTPVMMGTALGNTGIQHVLDAIVDYLPNPSEVLNTGLDLSKNEAKVPLVPSIQQPFVGLAFKLEEGKYGQLTYIRVYQGRLRKGNYITNIKTGKKVKVSRLVRMHSEEMEDVDEIGSGEICATFGIDCSSGDTFTDGNVKYSMSSMYVPDAVVSLSIKPKSKDSTNFSKAFNRFQKEDPTFRVKFDPESKETVISGMGELHLEIYVERMKREYNVECETGKPQVSYRESITIPAEFDYTHKKQSGGAGQFGRVIGTMSPVEGETRDNLFETAIVGGRIPDKYLAACGKGFEEACEKGPLVGHKVLGVKMLINDGAIHAVDSNELSFKTATMAAFRDAFLKSQPVVLEPIMNVSVTSPNEFQGNVIGLLNKLQAVIQDTENGHDEFTVKAECSLSTMFGFATSLRASTQGKGEFSLEFSHYAPTPPHVQKELMAEYAKKQKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PA_I73A4
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFINELGESVIIESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTRAEKPKFLPDLYDYKENRFVEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADYSLPPNFSSLENFRAYVDGFEPNGCIESKLSQMSKEVNTRIEPFSKTTPRPLRTPGGPPCYQRSKFLLMDALKFSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLQAWKQVLAELQDLENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDISDLKQYDSDEPETRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHNWEKYCVLEIGDMLLRTAVGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMTEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKILLIVQALRDNLEPGTFDIGGLYESIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: APT_ACIC1
Sequence: MPPADIGELVAAHIRDIPDYPSPGIVFKDITPLLAEPAVFAAVVDALVRDYQHGTVDKVVGIEARGFIVAAPVAYHLGAGFVPMRKKGKLPYRTLETSYALEYGTATIEVHVDAFRPGDRVLVVDDVLATGGTAAAALELIDQASAKAVGLSFLIELSALGGRSRLPASMVRSLLRV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_SYMTH
Sequence: MTRLLMLLVRFYQRYLSPLKGGPTCRFTPSCSQYAYEALAKYGAIKGTWLAVRRVLRCHPFHPGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRUB_STRT1
Sequence: MISGIINLKKEAGMTSHDAVFKLRKILHEKKIGHGGTLDPDVTGVLPIAVGKATRVIEYMTEAGKVYEGEITIGFSTTTEDASGEVVQTTPITELDGATVDQAMASFEGEITQIPPMYSAVKINGKKLYEYARAGEEVERPQRQVKITEFVRTSPIELENGTARFTFRVACSKGTYVRTLSVDLGVKLGFASHMSALRRTASAGLTLDSSLSLSQISEMVEAGDQSFLLPIEFGVQDLPAVQVTEDDAKEISFGRFISINSQEPLVAAFLGNKVLAIMEKRGQVYKPRKVLSQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FPG1_MYCTO
Sequence: MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase 1, Fapy-DNA glycosylase 1, DNA-(apurinic or apyrimidinic site) lyase MutM 1, AP lyase MutM 1.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: YHAO_BACSU
Sequence: MLTDLTFIHAADLHLDSPFYGISHLPEPIFARIKESTFASVRHMIDAAVREHVDFILLAGDLFDEANRSLKAQLFLKKQFERLRECGISVYVIFGNHDHLGGEWTPIEWPENVHIFSSAVPEEKSFFKEGRRIASIYGFSYQARALMENQAARYRRSTDAPFHIGMLHGTLSGSEGHDPYCPFTHDDLVKSGMDYWALGHIHKRQVLSAEHPAVIYPGNTQARHIKETGDKGYYLVHVTNGDISYEFQRAHDVLWEKAAVDVTEAKNMTALFQMVEDTFSKLRKKGSPVCVRLVLQGTAPEWLLEAPKGTLDEFLEALQEQEAEEERFVWPLRLDDETENEANLTNLDPFFGGLFEDIDRSDLSDVLEGLERHPVYRRHADRFSQEEVKEIKEQAQIILKRQLKVLDT
What are the official names of this protein?
Uncharacterized metallophosphoesterase YhaO.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
Protein: OBP1A_ARATH
Sequence: MEKAVHLSTKNGPKVPGEPTKTGTSMVDTAASAVQSFAPINQIHQHLCAFHFYAYDMTRQVEAHHFCGHINEDMRQCLIYDGPDANARLIGLEYIVTEKLFMTLPDDEKKLWHTHEWEVKGGFLFMPGVPEAIQRQDLEKVAKTYGKVYHFWQVDLGHQLPIGLPNIMMAVTRDGQLYPEMIKETEKQFGVSIDKERESRAYMKGPDHGIHPLANGGGKGLKLELREVDIKPVESVPRVFV
What are the official names of this protein?
Oil body-associated protein 1A.
What is the protein family that this protein belongs to?
Belongs to the OBAP family.
What are the subcellular locations of this protein?
Lipid droplet.