PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_SALTI
Sequence: MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGTQLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGVWVIGDRHDLSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIEQESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TPT_PEA
Sequence: MESRVLSRATTLSSLPTLNKLHRLPLANASLPSVKSFGSVSDGGNLVWGRQLRPELCSPVLKKGASLLRPCPATAGGNDSAGEEKVAPVGFFSRYPALTTGFFFFTWYFLNVIFNILNKKIYNYFPYPYFVSVIHLAVGVVYCLVSWTVGLPKRAPIDGNLLKLLIPVAVCHALGHVTSNVSFAAVAVSFTHTVKALEPFFNAAASQFILGQSIPITLWLSLAPVVIGVSMASLTELSFNWLGFISAMISNISFTYRSIYSKKAMTDMDSTNIYAYISIIALIVCIPPALIIEGPTLLKTGFNDAIAKVGLVKFVSDLFWVGMFYHLYNQVATNTLERVAPLTHAVGNVLKRVFVIGFSIIIFGNKISTQTGIGTGIAIAGVALYSFIKAQIEEEKRQAKAA
What is the function of this protein?
Mediates the export of fixed carbons from the chloroplasts into the cytosol in the form of triose phosphates.
What are the official names of this protein?
Triose phosphate/phosphate translocator, chloroplastic, cTPT, E30, p36.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein. Note=Located in zones of contact between the inner and outer membrane of the chloroplast.
Protein: NUOCD_YERPN
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHRQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS9_THENN
Sequence: MASVIGYYGTGRRKTAVARVYLRPGDGKVKVNGKEYESLNDYFKNIAWTKHAIEPLEVTNTIGKFDLVIRVNGGGLSGQAGAVRLGIARALLQYDENLKPVLKKYKMLTRDPREVERKKYGLKKARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: VPRL_FIVSD
Sequence: MEVIRIFNKVAERLDKEAAIRIFVLAHQLERDKLIRLLQGLLWRLRFRKPKSKDCLCWFCCRLYYWQLQSTLSIDTA
What is the function of this protein?
Seems to function as a Vpr-like protein, since it mediates host cell cycle arrest in G2 phase.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production.
What are the official names of this protein?
Probable Vpr-like protein, ORF2, OrfA, Protein Tat.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Contains both nuclear import and nuclear export signals.
Protein: PANC_RALPJ
Sequence: MKVISSIQELRDQLRGQNRVAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQKEGVYVLFAPTERDMYPEPQEYRVEPPHDLGDTLEGEFRPGFFKGVCTVVMKLFCCVQPRVAVFGKKDYQQLMIVRRMAHQFALPVDIVPAETVRADDGLALSSRNVYLTNEERAEAPELYRTLHQVRQDVLETVLQGQASHEEVTTKAMDYLRGRGWQPDYVAVRRRSDLQKPTPENIAAGEPLVVLTAAKLGKTRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_SALTO
Sequence: MGERTWPHLLAALLRGDELCTADTAWAMGEIMSGSAGPAQIAGFAVALRAKGETPTELAGLVEAMLTHAVPVNLPAELRATAVDVVGTGGDLAHTVNISTMASLVVAGAGVRVVKHGNRAASSSCGTADVLEFLGLPLDLGPEAVATCVAEAGIGFCFAARFHPGMRHAGPVRRELGVPTAFNFLGPLTNPARPRAGAVGCFDARMAPVMAAVFAARGDSALVLRGEDGLDEFTTAAPTRVWAAQDGTVREALLDATDLGIPRATLADLRGGDVAYNAEAVRRLLAGETGPVRDAVLVNAAAALATQGPLDADLTEALQAGLLRAADSIDSGAAARTLERWIDVAQTVRPAAV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YHEA_BACSU
Sequence: MAVNFYDVAYDLENALRGSEEFTRLKNLYDEVNADESAKRMFENFRDVQLRLQQKQMAGEEITQEEVTQAQKTVALVQQHEKISQLMEAEQRMSMLIGELNKIIMKPLEELYGSVEG
What are the official names of this protein?
UPF0342 protein YheA.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: SERB_SCHPO
Sequence: MVNAAIVVSSNRPNVLEQISSLFRDGKTRSLGEQWTLVSGQLKGTFEDAKDACNRISATENVDCNCLSEATFSTKKKLVVFDMDSTLIQQECIDELAAEAGIQKEVATITSLAMNGEIDFQESLRRRVSLLQGLSVDVINKVIGKITFTPGAKQLCHCLKQMGATLVVASGGFVPMAEYVKGQLDLDYAYANVLEFSDDGKFLTGKVQGAIVDGQRKASILREKREELGLNKLETMAVGDGANDLVMMAESGLGIAFKAKPKVQLLADSKINLPSLQNALYLLGIDEQQQKKLLENKN
What are the official names of this protein?
Probable phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: T229A_MOUSE
Sequence: MAGSDVASEGPSPRDGATRRPGATGGLRSQAAASCPEPLSAAEAPAERGALPAWMRLYFYGMHGITLDVLVSSARRFARSLDLRMLGFSSPYRCLLHSLTHFALEQLYLQRPRCPSAFLFNFLLYPSAHVGLQTLAGQALRLSLGGGPGGAAAPALGALDLALQYVLALYHGQVFLKRFLCLRYPRRRDQHTRDTLPAARDAQILWEAGGQRRGPGGARGTERSPTQGLPDLLRFLFFGMHGFLDEIFFTFFFNVLGQGDRASSGHTSLWSFFMYGSCSFVVEKLYFHLHYSRGWGTWKRVPIYVIFIYAWEFSWGLGLRMCGACSWDYSHYPLNFMGLITLMYLPGWLFLSVYQDLLSNVLWRVQYVPTN
What are the official names of this protein?
Transmembrane protein 229A.
What is the protein family that this protein belongs to?
Belongs to the TMEM229 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: REX_HALH5
Sequence: MNNEPTKIPQATAKRLPLYYRFLENLHASGKQRVSSSELSEAVKVDSATIRRDFSYFGALGKKGYGYNVNYLLTFFRKTLHQDELTKVMLIGVGNLGTALLNYNFSKNNHTQIVMAFDVDREKIGNTVSGVKIENLDNLENKITSDVSVAILTVPAAVAQKTADRLVNAGVKGILNFTPARIAVPEHVRVHHIDLSVELQALIYFLKHYPL
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
Protein: Y091_BUCAP
Sequence: MNKNRQLAVNSNILFRKWLNGTREMVQDTIFHSRLHKVNQKIRSKRMFFEQDVHSNYFSFYKKKDFFKENPVSYVRNKDFTNVLKKLKKGKYYPDIFLDLHGLNQYQARKKLGQLIAICQKEKMFCAHIMHGYGKNILKKQIPFWLSQHPDIVAFHQAPKMFGNDAAIMVIIEIHS
What are the official names of this protein?
UPF0115 protein BUsg_091.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: ATPE_SULSY
Sequence: MYRLDVVTPTGSVFSGDVYQTVITTADGEIGILENHMLLLTNITPGKLRIEKADGEVKEFAVTYGVLDVRGDKVIALVEEVFELDEINVDNEKQLLEEANQKLQNENLSEEEKEHYEKQRSRSQALLNLASAKV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPG21_MACFA
Sequence: MGEVKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGINQEEQ
What is the function of this protein?
May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
What are the official names of this protein?
Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_SIVMB
Sequence: MKAMETQRNCRTLSLKEIILCTLVLGIIGIIKCEDNMWVTVYYGVPVWREADTTLFCASDAKAQNPEVHNVWASQACVSTNPNPEEIELTNVTEYFNAWENNMVEQMHEDIVNLWDQSVKPCVKLIPLCVTLNCSLFKCIKENGNTTNCTVQISTGNDSTANNITVGTIDMYNCSFNATTELRDRKKQVYSLFYRQDLEPLEGNKPPEGDKNALYRLYNCNTTAMTQACSKVSLEPIPIHYCAPAGFALLKCNDKNFTGIGQCKNVSTVHCTHGIRPVVSTQFLLNGTLEEKVTVLDRNVSNDMDTIIVKLNETVRLNCTRTGNNTIKGIPIGPSQIFYGIETVIGDTRQAFCQLNKTVWTNTFKKVRHALNETYKGYLGNETITFGPSTGGDLEVTNLHLICGGEFFYCNTSILFNTSIIFNETKDDNITIPCRIRQIVRLWQRVGRGIFLPPIRGTINCISNITGILFAQQKTDRMNKSAMFTPVGGEMRNNWRSELYKYKVVRIEPLGVAPTKAKRRTVHREKRAAVGLGALFLGFLGAAGSTMGAASLTLTVQARQLLSGIVQQQSNLLRAIEAQQHLLQLSVWGIKQLQARVLAVERYLKDQQLLGLWGCSGKLICTTSVPWNTTWTNKSYDDIWYNMTWMQWDKEVSNYTDVIYNLLEKAQTQQENNEKELLELDKWASLWNWFDITSWLWYIKIFIIIVGGLIGLRIVFALLSIVNRVRQGYSPLSFQTLIPARRDRDRPEEIEEGGGEPDNVRSIRLVSGFLALAWNDLRDLCLFLYHRLRDLLLIVLRTLELVGQTLLKGLRRGREALIHLRGILQYWGQELKTSAISLLDTTAIAVAEGTDRIIEIAQRFGRGILNIPRRIRQGLERALL
What is the function of this protein?
Oligomerizes in the host endoplasmic reticulum into predominantly trimers.  In a second time, gp160 transits in the host Golgi, where glycosylation is completed.  The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: VSP2_AGKCO
Sequence: VVGGDECNINEHRFLVAIFNSNGFVCSGTLINQEWVLTAAHCDSTDFQIKLGAHSKKVLNEDEQIRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIAPLSLPSSPPSVGSVCHIMGWGSITPIEVTFPDVPHCAYINLLDDAACQPGYPEVLPEYRTLCAGILEGGKDTCNYDSGGPLICNGQFQGIVSYGAHPCGQSLKPGIYTKVFDYNDWIQSIIAGNTAATCPP
What is the function of this protein?
Thrombin-like snake venom serine protease that cleaves beta chain of fibrinogen (FGB), releasing fibrinopeptide B.  Has a coagulant activity activating blood coagulation factors V (F5) and XIII (F13A1).
What are the official names of this protein?
Thrombin-like enzyme contortrixobin, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP, Venombin B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OR2T1_HUMAN
Sequence: MWQEYYFLNVFFPLLKVCCLTINSHVVILLPWECYHLIWKILPYIGTTVGSMEEYNTSSTDFTFMGLFNRKETSGLIFAIISIIFFTALMANGVMIFLIQTDLRLHTPMYFLLSHLSLIDMMYISTIVPKMLVNYLLDQRTISFVGCTAQHFLYLTLVGAEFFLLGLMAYDRYVAICNPLRYPVLMSRRVCWMIIAGSWFGGSLDGFLLTPITMSFPFCNSREINHFFCEAPAVLKLACADTALYETVMYVCCVLMLLIPFSVVLASYARILTTVQCMSSVEGRKKAFATCSSHMTVVSLFYGAAMYTYMLPHSYHKPAQDKVLSVFYTILTPMLNPLIYSLRNKDVTGALKRALGRFKGPQRVSGGVF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2T1, Olfactory receptor 1-25, OR1-25, Olfactory receptor OR1-61.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSG_ECO5E
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARHIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: SSRP_SYNSC
Sequence: MAKGGAKKAAAAAARAAANRMLADNRQARHQYEILETLETGIELVGTEVKSIRNGKANLRDGFCLIRNGELQLHNVHISPHTHAGNYFNHDPLRTRKLLAHRREIDKFRGLVDQKGLTLIPLSLQLKGSWIKLTIGLGKGRKLHDKRAAEKEKQSKKDVKAAMERY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GMPPA_DICDI
Sequence: MTTTTTKAIILVGGPSKGTRFRPLSLDVPKLLFPIAGKPMIYHHIEACSKVENMKEIILIGFFQESVLSKFISETSKQLNVAIRYINEEKVLGTAGGLYHFRDIILEGGPSEIFVLHSDICCAFPLNDLLQFHKQHGRSCTIMGTEIESAYANQYGCLVRDEKTAELLHYAEKPETFVSNLINCGVYCFSPQFFDVIGKTMIDLKTSGQNITTDYPEITRKGFDVERLRLEQDIFVPLAGTGFISVYPYVGFWRQIKNAGSSVYCQELYLNHFAKTKPEVLKKGNNIIGNVIIDSTASVDPSAIIGPDVYIGPNVKIGKGVRVIHSIILDQTEIKDHACIIYSIIGWQSLIGVWARIEGIPNYTPFLYSQDKRRGVTIFGAGAQANGEIIVSNCIVMPHKQLDRNYNNEIIL
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase alpha, GDP-mannose pyrophosphorylase A, GTP-mannose-1-phosphate guanylyltransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: HTXC_STUST
Sequence: MNQRIEEVMLANVKRDVARRKRHFATSVVVLSLLAVAWYVCQIEFQKLGAGLPRLWSFVVQMFPPDLSDLDVILKGAGETLAMATIGTIFATIIAFPLALMAARNTCPNKWTYRVSRAILNASRGTETFVYALVFVAAVGFGPFSGVLAITFHMVGAIGKMFAEAIEPVDQGPLDALALTGASRAKIIRYGLIPDVMPHLIASVLYIWEFSVRTSTVLGIVGAGGIGQTLKDTVDLLEFNKMITVLAVVLLMVSAIDFISDRLRYLILDTKREGFETLPANN
What is the function of this protein?
Probably forms part of a binding-protein-dependent hypophosphite transporter.
What are the official names of this protein?
Putative phosphite transport system permease protein HtxC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
Protein: RS10_CLOBA
Sequence: MSKQKIRIRLKAFDHTILDQSAEKIVETAKTSGAKVVGPVPLPTEKDVVTILRAVHKYKDSREQFEIRTHKRLIDIVNPSPKTVDALMRLNLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ASH1_YEAST
Sequence: MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRNNITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISSLTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQQSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVAHFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFKDLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSNNDSIFNPIISEKLVQEVKHQRQLRGNSFPMPNASHKKTNSFKALQIKKLLANRDILSNNSKSNVRKPSKNKISKQASNVFGNTARQLVMKLDNASYSSVSASSSPSPSTPTKSGKMRSRSSSPVRPKAYTPSPRSPNYHRFALDSPPQSPRRSSNSSITKKGSRRSSGSSPTRHTTRVCVSCHSSDSPCWRPSWSPRKQDQLCNSCGLRYKKTHTRCLNDLCRKIPTKGEINIMKSNGIDKEFVPERNCEIEGYRCLFCNYITETVEN
What is the function of this protein?
Component of the RPD3C(L) histone deacetylase complex (HDAC).  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites.  Also involved in pseudohyphal growth.
What are the official names of this protein?
Transcriptional regulatory protein ASH1, Daughter cells HO repressor protein.
What are the subcellular locations of this protein?
Nucleus. Note=Preferentially accumulates in daughter cell nuclei at the end of anaphase.
Protein: NDK1_PSEMZ
Sequence: GLVGEIISRGDFAIDIGR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: RECR_STRPM
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHGYYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: ERB1_BOTFB
Sequence: MAPPTNQRKRKAVTRDEPEISDVESEAEFGDGILEGILSQSEDESDDSAAEEDSEDEEDLDEEELEALDSDEVPSENGEGEGSMTRTSLNKINADEDDDKPNYTVVKDANGGERYVYEEINPVYDSDDSDAQEPTNTIGNIPLSFYDSYPHIGYDINGKKIMRPAKGEALDALLDSIDIPKGWTGLTDPSTGKPLNLTQEELEVLRRIQTNEVPEDGYDPYPDYVPYFSGVEEIMPLSSAPEPKRRFLPSKHEAKRIMKIVRAIREGRILPYKPPQEREEEEEEHHYDIWQNEEAQPDHIMKIPAPKPPPPGYDLSYNPPPEYLPSKAERKEWEATDPEDREKEYLPTAYDSLRKVPGYDKFINERFERSLDLYLAPRVRKNRLNIDPASLLPKLPKPEELKPFPTVTQTLFRGHDGRVRSLAIDPSGTWLATGGDDGTVRVWELLTGKQLWSAQIGDEEAVNVVKWRPAKDAIILSAAAGDDIFLMVPTIIDPVAESNSRELLDAGFGYATNATQALTANGQKKEPVATWARPTSRLQDEGVLIKITVRSTVKVINWHRRGDFFSTVSPTAQKSAVAIHTLSKHLTQIPFRRLPGIAQTAQFHPSRPIFFVATQRTIRSYDLQKQELVKIIQPGARWISSFDIHPGGDNLIVGSYDRRLLWHDLDLSTRPYKTMRFHNKAIRAVKYHKGGLPLFADASDDGSLQIFHGKVVSDAMENATIVPVKVLKGHKVKSALGVMDLDWHPKEPWLVSAGADGTCRLWT
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein erb1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: HRCA_BACMK
Sequence: MLTERQLLILQTIVDDFIGSAQPVGSRTLAKKDEITFSPATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPTDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGIPMAELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANMLSQPEFHDIHKVRSLLTMIDNEAAFYDILRHKQVGIQVKIGRENSSTAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: XERC_MYCTA
Sequence: MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML20_ARATH
Sequence: MSSIYRTVSRKEKPRRHHGLTTQKKQEIKEAFELFDTDGSGTIDAKELNVAMRALGFEMTEEQINKMIADVDKDGSGAIDFDEFVHMMTAKIGERDTKEELTKAFQIIDLDKNGKISPDDIKRMAKDLGENFTDAEIREMVEEADRDRDGEVNMDEFMRMMRRTAYGGN
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML20, Calmodulin-like protein 20, Centrin 1, AtCEN1.
Protein: DEF_PROM1
Sequence: MAGSFAQLAKNAEKKKPSISVSKEPVENPPLKVYQLGDEALRTPANRIVKVDDAIRKLAKDMLITMYSSKGIGLAAPQVGIQKRLLVIDLNFEDPNSPPMVFINPEIISSSATVDTYEEGCLSIPGVYLNVLRPSSIKLSYRDEMGRPKKMNADGLMARCIQHEIDHLNGVCFVDKVTDEEELKKQLNENNFKRSDVIKATN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.