PharMolix/UniProtQA huggingface dataset:
Protein: RL2_BORBU
Sequence: MGIKTYKPKTSSLRYKTTLSFDDLSKGNDPLKSLTKGKKFKSGRDSSGRISIRRRGGGHKRKYRLIDFNRRDKFSIPARVASIEYDPNRSANIALLVYKDGEKRYIISPKGIKVGDVLESGPNAPIKIGNALPLENIPIGRTVHNIELNVGKGGQLIRSAGGYAMILASDGNYVTVKLSSGEMRLIFKKCIATIGEIGNEDYANISIGKAGKSRWLGRRPKVRGVAMNPVDHPHGGGEGKTSGGRHPVSPWGQPTKGYKTRKKKRYSDKFIIKRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL19_CAMHC
Sequence: MRNKYIEAFENAQISNKNVPDFRAGDTLKLAIRIKEGEKTRIQNFEGICIARRGSGVGETFIVRKIGANGIGVERIFPIYSESLENIEVLRKGNVRRSKLFYLRDRRGKAAKIKELRK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DEAH9_ARATH
Sequence: MAFWKPGTEKPRFEEDGEGGIVFMSNNLASSSSSSYGYANIEKQRQRLPVYKYRTEILYLVENHATTIIVGETGSGKTTQIPQYLKEAGWAEGGRVIACTQPRRLAVQAVSARVAEEMGVNLGEEVGYTIRFEDHTTSGVTSVKFLTDGVLIREMMEDPLLTKYSVIMIDEAHERSISTDILLGLLKKIQRRRPELRLIISSATIEAKTMSNFFNSSKKRHAPEGSTPGPKLEPAILSVEGRGFSVKIHYVEEPVSDYIRSVVSTILLINEREPPGDVLVFLTGQEDIETAIKLLEEEAHSNQKNSSGLLPLPLYSGLSRSEQELIFTPTPRGKRKVILSTNIAETSLTLEGVVYVIDSGFSKQKFYNPISDIESLVVAPISKASARQRSGRAGRVRPGKCYRLYTEDYFLNQMPGEGIPEMQRSNLVSTVIQLKALGIDNILGFDWPAPPSSEAMIRALEVLYSLQILDDDAKLTSPTGFQVAELPLDPMISKMILASSELGCSHEIITIAAVLSVQSVWIIARGVQKEQDEAKLRFAAAEGDHVTFLNVYKGFLESKKPTQWCYKNFLNYQSMKKVVEIRDQLKRIARRLGITLKSCDGDMEAVRKAVTAGFFANACRLEPHSNGVYKTIRGSEEVYIHPSSVLFRVNPKWVVYQSIVSTERQYMRNVVTINPSWLTEVAPHFYQNRQNAMSF
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH9, DEAH RNA helicase homolog DDX35.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX35 sub-subfamily.
Protein: RL28_FRATF
Sequence: MSKVCIVTGKRPATGNNVSHAQNKTKRRFLPNLHAHRFWVESENRYIKLRVSSKGMRIIDKKGIDTVLSDLRAQGHKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NIA_VOLCA
Sequence: MTIPELPLGGIVSQAVELGAPYEPPLTPDHPEWKVHVPAAAVDKKDQDTPDNWVRRDPRILRLTGRHPLNCEPPMDVLMEYGFITPPAVHFVRNHGAAPRIPWAEHRIEINGLVDKPLFLTMDELVALPSITFPCTLVCAGNRRKEENMLKKSIGFNWGPCATSTTYWTGVRLRDLLLLAGIKSPEQGANFVCFRGPKGELPRGSDGSYGTSLTYAKAMDPSSDVIIAYKQNHRWLTPDHGFPVRMIIPGFIGGRMVKWLSEITVTEVESQNFYHFMDNRVLPSHVDEALAKEEGWWYKPEFIINDLNINSAVARPWHDEVVRLDANKPYTMRGYAYAGGGRKIIRCEVSLDDGKTWRLGDIQRFEKPNEYGKYWCWVHWSLDVMTFDFLNAKEVLLRAWDETMNTQPAIITWNVMGMMNNCYYRIKIHPQVDSDGVMGLRFQHPAPVELGERGNMGWREEDNLVAQALAAVKEGATAAAAPAAPPPVVAAAANGGPRQYTMEEVAAHNTEESCWFVHGGKVYDATPYLDEHPGGAESILIVAGADATDEFNSIHSSKAKAMLAQYYIGDLVASKPAAAGATVPEPQPVASTSSPAVDPLVVLNPRQKVKLPLIERIELNRNTRIFRFGLPSPQHRIGLPVGKHVFTYATINGENVMRAYTPISGDEELGRLDMLIKVYFANEHPAFPDGGKMSQHFESLRIGDTVEFKGPLGHFVYDGRGSYTLNGKLHKHATHMSFVAGGTGITPCYAVIKAALRDPEDKTQISLVFANNTEEDILLREELDELANNHPDRFHLWHTVSQTNSSDWKFSTGRVTLEMFKQHLFACSGPECLALMCGPPAMLEHCCVPFLESMGYSKEQMIHF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: DADA_BORBR
Sequence: MHVIVLGSGVIGTTTAYYLARQGAQVTVLERRAGPADETSYGNAGQVSPGYSTPWAAPGIPLKALKWMFQKHAPLAIRADGSFYQWRWLAAMLANCSAGRYSVNKERMLRLAEYSRDCLRTLRADTGIQYEQRTQGTLQLFRTAAQMEAARRDIAVLEECGVPYELLDRNRLPTAEPALARALDKLAGGLRLPNDETGDCRRFTLQLADKAKALGVQFRFNQQVEGLDVRGGQVAGVRVGGEQLAADRYVAAFGSYTRGFLRPLGLDLPVYPVKGYSLTIPMTDESAAPVSTILDETYKVAVTRFDQRIRVGGMAELAGFDLRLKEARRKTLELVVNDLFPGSGAVEQAEFWTGLRPMTPDSTPIIGATKYGNLFLNTGHGTLGWTMACGSGQLVADQVCGRQPAIRADDLALSRYGAGGQAGGGVARAQHNAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: TRPA_BACLD
Sequence: MFNLKKQPSDKLFVPFITAGDPLPEISIELAKSLQEAGASALELGVPYSDPLADGPVIQRASKRALDNDMNIVKAIRLGGEMKKNGVHIPIILFTYYNPVLQLDTDHFFALLRQNQLDGLLVPDLPFEESVYLQQQCKKHGITYISLVAPTSESRIQKITQQAEGFVYCVSSLGVTGVRNEFEDSVSSFIRSVKGMSSVPVAVGFGISSSKQVEMMNELADGVVVGSALVRKIEELKDELVAPETREQALKAFEAYAKTFSGSYMVK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: THIG_SHESA
Sequence: MLTIAGVEFESRLFTGTGKFSSSQLMLESIKASKSQLVTVAMKRIDLKTGADDLLSPLRQAGVRLLPNTSGARNAKEAIFAAELAREMLGTQWVKLEIHPDPKYLMPDAVETLAAAKTLCERGFIVMPYVHADPVLCRRLEEVGCAAVMPLASPIGTNQGLVTEPFIKMIIEQAKVPVVIDAGIGTPSHAAHAMELGADAVLVNTAIASSASPIEMAQCFKDAVDCGRRAFEAGLGRVQTQAVHTSPLTGFL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3962_BURL3
Sequence: MSKPSDRINLTNQFLIAMPNMADPTFSGTVVYLCDHSERGALGLVINRPTDIDLESLFNRIDLKLDIEPLLHIPVYFGGPVQTERGFVLHEPVEGASYNSSMSVEGGLEMTTSKDVLEAVATGTGPKRFLLTLGHAGWGAGQLEEEISRNGWLTVAADPRIVFDTPAEERFEAALGLLGVSSSMLSGEAGHA
What are the official names of this protein?
UPF0301 protein Bcep18194_A3962.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: TYPH_KLEP3
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMSMPERVSLTMAMRDSGTVLNWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSAALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAADDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYDHYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDHVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLDDKAPEITPTVYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: MINC_BURMA
Sequence: MSLKKSPFFELRSGSVDTLLFIVKTADLDALRAELVKRFEATPEFFADDVVAIDVRRLADHERVPLDDIRGMLNDVRMRVIGVVAQPEQHAWAASAGLPLLEARDRRAPSSKAADEAPVQQAEPAAPAAGQAALFEQAGPTLADAGAPPESPAPAVAAQSATLVVDRPLHSGQQIYAKGDLVVLGPVSYGAEVIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEPELISIAGIYRTTENPLPADVLGKSVQIRLEQEKLMIEPLRLT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: TPH1_RABIT
Sequence: MIEDNKENKDHSLERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDTNREQLNDIFHLLKSHTNVLSVTPPDNFTMKEEGMESVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMSYKYGDPIPKVEFTEEEIKTWGTVFRELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDISNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHVLSGHAKVKPFDPKITYKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDAKSITNAMNELRHDLDVVSDALGKVSRQLSV
What is the function of this protein?
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
What are the official names of this protein?
Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: NANK_ECO7I
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQVHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTDLPTIAINDAQAAAWAEYQALEGDITEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTHAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLALGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: RL28_DESHD
Sequence: MANVCAICGKGVASGIQVSHSHIRTKRTWKPNLQRVHAIVNGTPTRISVCTRCLRSGKVQRAV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LIPB_DICTD
Sequence: MKKLLVIDFKEKIKYEDAWNFQRKLHDLRVNNIIYDTLILLEHFPVITLGKFGNESNLLKRKEELEDIGIDFLRVDRGGDITYHGPLQLVGYLIFRVEGVKNFVLKIERSIINVLNEYGIEAKENLKYPGVWVGDRKIAAIGIAIKKKVSYHGFALNVSNDLTPFSYIIPCGLKDKKVTSILKEADFSPSMEDVKKKVCLSVVREFGFDSFKVFNFSSYKELSNFDMLLEDQ
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC_STRCO
Sequence: MSDANNTAGDANEVNPEKDLSAENLPGQRGQGGEEIRVQRGMFGANNGGDTSGYGGLVRSVRLPGPASRPYGGWFDEVADELEGALEEQGLLPDNAIEKTVVDRGELTFHIEREHLVRVARTLRDDPALRFELCTGVSGVHYPHDKGRELHAVYHLRSITHNRLIRLEVSAPDGDPHIPSLVSVYPTNDWHERETYDFFGIVFDDHPALTRIMMPDDWQGFPQRKDYPLGGIPVEYKGAQIPAPDQRRSYS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: 3MGH_CHLTE
Sequence: MKRLGADFYQMPTILLAERLLGKIFVHHEVSGRVTKGRIVETEAYLGDGDEACHAWRGMTERNHVMFGPPGHLYIYFSYGCHYLANIVSEQKGIAGAVLLRAMEPIEGIEWMQERRGTTDERALMSGPGKLTQALGLGPAHYGESLLGDICWLEEAPDIPPELIGTSPRIGISRSTDLLWRKFIAGSPYISKTQPGPPPKKRKKGLESS
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: CADH2_PSEMZ
Sequence: CGILGLGGVGHMGVKAFGLHVTVISSSDKFVVDVAASNLDK
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers, like coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol (By similarity).
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 2, CAD 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: CXCL6_BOVIN
Sequence: MRLLSSRAARVSGPSGSLCALLALLLLTPPGPLASAGPVAAVVRELRCVCLTTTPGIHPKTVSDLQVIAAGPQCSKVEVIATLKNGREVCLDPEAPLIKKIVQKILDSGKNN
What is the function of this protein?
Chemotactic for neutrophil granulocytes.  Signals through binding and activation of its receptors (CXCR1 and CXCR2).  In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7) (By similarity).
What are the official names of this protein?
C-X-C motif chemokine 6, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DICH_DROME
Sequence: MATLSTHPNYGFHLGQAQGLEDYAPQSQLQLSPGMDMDIKRVLHYSQSLAAMGGSPNGPAGQGVNGSSGMGHHMSSHMTPHHMHQAVSAQQTLSPNSSIGSAGSLGSQSSLGSNGSGLNSSSGHQSAGMHSLATSPGQEGHIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKNPLTAGPQGGLQMQAGGMGQQKLGAGPGAGAGGYNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAAVNNQGQQQGQAPPQLPPTSLSSFYSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGTITPNGMDGSMDSALRRPVPVLY
What is the function of this protein?
Essential for segmentation and CNS development.  May modulate the actions of other transcription factors, including gap and pair-rule proteins.
What are the official names of this protein?
SOX domain-containing protein dichaete, Protein fish-hook.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTC_ECO44
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: PG117_MONPV
Sequence: MDAAIRGNDVIFVLKTIGVPSACRQNEDPRFVEAFKCDELERYIDNNPECTLFESLRDEEAYSIVRIFMDVDLDACLDEIDYLTAIQDFIIEVSNCVARFAFTECGAIHENVIKSMRSNFSLTKSTNRDKTSFHIIFLDTYTTMDTLIAMKRTLLELSRSSENPLTRSIDTAVYRRKTTLRVVGTRKNPNCDTIHVMQPPHDNIEDYLFTYVDMNNNSYYFSLQRRLEDLVPDKLWEPGFISFEDAIKRVSKIFINSIINFNDLDENNFTTVPLVIDYVTPCALCKKRSHKHPHQLSLENGAIRIYKTGNPHSCKVKIVPLDGNKLFNIAQRILDTNSVLLTERGDHIVWINNSWKFNSEEPLITKLILSIRHQLPKEYSSELLCPRKRKTVEANIRDMLVDSVETDTYPDKLPFKNGVLDLVDGMFYSGDDAKKYTCTVSTGFKFDDTKFVEDSPEMEELMNIINDIQPLTDENKKNRELYEKTLSSCLCGATKGCLTFFFGETATGKSTTKRLLKSAIGDLFVETGQTILTDVLDKGPNPFIANMHLKRSVFCSELPDFACSGSKKIRSDNIKKLTEPCVIGRPCFSNKINNRNHATIIIDTNYKPVFDRIDNALMRRIAVVRFRTHFSQPSGREAAENNDAYDKVKLLDEGLDGKIQNNRYRFAFLYLLVKWYKKYHIPIMKLYPTPEEIPDFAFYLKIGTLLVSSSVKHIPLMTDLSKKGYILYDNVVTLPLTTFQQKISKYFNSRLFGHDIESFINRHKKFANVSDEYLQYIFIEDISSP
What is the function of this protein?
Multifunctional protein required for genome uncoating and replication.  Major viral uncoating protein that is required for the release of the viral genome from incoming viral cores containing the viral DNA genome.  Possesses an ATPase activity that is required for hexamerization and uncoating.
What are the official names of this protein?
Uncoating factor OPG117.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG117 family.
Protein: SYS_BRUC2
Sequence: MLDIKWIRENPETLDKALAKRGAAPLSSELIALDEKRREHVGKVQAAQERRNAASKEIGKAMAAKDMGTAEKLKAEVGELKDFLAHAEEDERRLSKELSDALSTIPNIPLDDVPLGKDESDNVELRRIGNPHNFSFQPKEHFELGEALGYMDFERAAKLAGARFTVLKGPLARLERALGQFMLDLHTTEHGYTEVMPPLMVRDEAVYGTGQLPKFSEDLFRTTDGRWLIPTAEVPLTNLVAEEIVDMKGLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFLKVEMVSITDAESSVAEHERMTACAEEVLKRLGLPFRTVVLCTGDMGFGAQRTYDIEVWLPGQNTYREISSCSTCGDFQGRRMNARYRPEGEKSTRFVHTLNGSGVAVGRALIAVMENYQQEDGSIHIPEALQPYIGGLTRIEKAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_PSEPK
Sequence: MTGYVQVGGLQVAKVLYDFVNNEAIPGTGIVAEQFWAGAEKIINDLAPKNKALLAKRDELQAKIDAWHQARKGQAHDAAAYKAFLQEIGYLLPQADDFQATTQNVDEEIAHMAGPQLVVPVMNARFALNAANARWGSLYDALYGTDAISDEGGAEKGQGYNKVRGDKVIAFARAFLDEAAPLAAGSHVDSTGYRIEGGKLVVALKGGSNTGLRDDAQLIGFHGDAAAPTAVLLKHNGLHFEIQVDASTPVGSTDAAGVKDILMESALTTIMDCEDSVAAVDADDKVIVYRNWLGLMKGDLAESVSKGGKTFTRTMNPDREYAAPNGGSVTLHGRSLLFVRNVGHLMTNPAILDAQGNEIPEGIQDGLFTNLIALHNLNGNTSRKNTRSGSVYIVKPKMHGPEEVAFATEIFSQVEDLLGMPRNTVKVGIMDEERRTTVNLKSCIKAAAERVVFINTGFLDRTGDEIHTSMEAGAVVRKGAMKNEKWIGAYENNNVDVGLATGLQGRAQIGKGMWAMPDLMAAMLEQKIAHPLAGANTAWVPSPTAATLHALHYHKVDVQARQRELASRTPASVDDILAIPLAADTNWSAEEIRNELDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISAQLLANWLRHGVVSQEQVLESLKRMAVVVDQQNAGDPLYRPMAPNFDDNVAFQAAVELVVEGGKQPNGYTEPVLHRRRREFKARNGL
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECG_SALTY
Sequence: MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAINAEKLLTAEDNPEVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMARAGKEGTPVFLVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASGAKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWLYRLLSQPRRITRQMRLLRYLRWHYTGDL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: S61A1_BOVIN
Sequence: MGIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMTITIGQSIVYVMTGMYGDPSEMGAGVCLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.  The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.  Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity).  Plays a critical role in nephrogenesis, specifically at pronephros stage (By similarity).
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: MNMG_SACD2
Sequence: MIYPTQYDVIVIGGGHAGTEACLAAARMGCKTLLLTHNIETLGQMSCNPAIGGIGKSHLVKEIDALGGAMALATDKGGIQFRILNSRKGPAVRATRAQADRALYKAAVREILENQPNLDIFQQAADDLVVEGERVTGVTTQMGVTFKAPTVVLTAGTFLGGKIHIGMENHSGGRAGDPPSIALASRLRELPLRVDRLKTGTPPRIDARSVNFDGLEKQWGEEKTPVMSYMGSLADHPEQTCCWITHTNAQTHDFIRSGFDRSPMFTGVIEGVGPRYCPSIEDKVNRFADKDSHQIFIEPEGLKTHELYPNGISTSLPFDVQMAFVRSIKGFENAHITRPGYAIEYDFFDPRDLKYSFETKHIEGLFFAGQINGTTGYEEAGAQGLLAGLNAALKAQGKEAWCPRRDEAYIGVLADDLISMGTREPYRMFTSRAEYRLLLREDNADMRLTEKGRELGLVDDARWQAFCKKREAIELETQRMRTTWIQPNSAEANALAAKMPAELAREYSLLDLLKRPELTYDDLGSLKGEAVSDPQVAEQVEINTKYAGYINRQTDDIERMRQHENTVIPVEFDYMSVEGLSNELKQKLSEARPETLSRASRIPGVTPAAVSLILIYLKKRGLLKNKAALA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYD2B_PYRFU
Sequence: MRYVKLHSEYFPEFFNRLKEVGRVYGPVRHNSTYRFEEVNSIDELSLDYTRTILPPKKFFIRPRDAMFKIQKNEVTEVDGDGKFVLFGVHSCDIHGIKILDKVYLSNPPDPYYERRRKNAFIVGISCMPDEYCFCKSLGTDFAMDGFDIFLHELPDGWLVRVGSVKGHEFVWENQDIFDDVTEEDLRNFKEFEEKRAKAFKKSLNKEGLADILDLAFTSKVWKKYAEKCLGCGNCTIVCPTCRCYEVCDTWVRAYEALRMRRYDSCFMPTHGLVAGGHNFRPTRLDRFRHRYYCKNYFDPEAGFNCVGCGRCDEFCPARIEHVKVLDEVREGLI
What is the function of this protein?
Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity.  May play a role in hydrogen cycling during fermentative growth.  Activity exhibited with NAD in addition to NADPH.  The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur.
What are the official names of this protein?
Sulfhydrogenase 2 subunit beta, Hydrogenase-II subunit beta, H-II beta, Sulfhydrogenase II subunit beta, Sulfur reductase subunit ShyB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_LISIN
Sequence: MAENAYSKAGVDVDAGYQVVERIKKHVARTERMGAMGALGSFGGMFDLSSLNLKEPVLVSGTDGVGTKLLLAIEADKHDTIGIDCVAMCVNDILAQGAEPLFFLDYIATGKTDPVKMEQIVKGVADGCEQAGAALIGGETAEMPDMYGADDYDLAGFTVGAVEKKKLITEGAVKAGDTLIGIPSSGIHSNGYSLVRKIFFKDNDFKLNEAFTELDVPLVEELLKPTRIYVKPVLEVLKAVDVHGITHVTGGGFVENLPRMLTNDLAVKVELGSWPVLPIFDLMKKYGQLSELEMYEIFNMGIGMVLAVAKEDVEKTLEVLVQNGEAAYVIGEVTTRSDDAVIFGGAKG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.