PharMolix/UniProtQA huggingface dataset:
Protein: N6MT1_MOUSE
Sequence: MAAPSVPTPLYGHVGRGAFRDVYEPAEDTFLLLDALEAAAAELAGVEICLEVGAGSGVVSAFLASMIGPRALYMCTDINPEAAACTLETARCNRVHVQPVITDLVHGLLPRLKGKVDLLVFNPPYVVTPPEEVGSRGIEAAWAGGRNGREVMDRFFPLAPELLSPRGLFYLVTVKENNPEEIFKTMKTRGLQGTTALCRQAGQEALSVLRFSKS
What is the function of this protein?
Methyltransferase that can methylate proteins and, to a lower extent, arsenic (PubMed:20606008, PubMed:26797129).  Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators (By similarity).  Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif (PubMed:26797129).  Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated (PubMed:20606008, PubMed:26797129).  May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid (By similarity).  It however only plays a limited role in arsenic metabolism compared with AS3MT (By similarity).
What are the official names of this protein?
Methyltransferase N6AMT1, HemK methyltransferase family member 2, Lysine N-methyltransferase 9, Methylarsonite methyltransferase N6AMT1, Protein N(5)-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal PrmC-related family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 218R_IIV6
Sequence: MAKYQHYAIFEAVKEFVTSLCDCYQDEVDEPLHMLKAYLNKLNISMKESTKIINETIDFCKRNSKAIDKKDVSLFESGDKGIIFDEEAFIDVIEYLQKEDENQSVILDHLNSINYLIDGGVTEEELFLNKFVTSFASSFNSSSVNIPEFSEEGVSDESIEAIGNVIKPTIEKSLEDFQTKNLNVDRFMKSISFKVKEYIEKNDIPGIHKNELHDILDMTIENDVSELFEKKFEIFAKLSSSGLLAHLPLDKIMTLVPSNMEDSVQSELNNLSLE
What are the official names of this protein?
Uncharacterized protein 218R.
Protein: Y2896_SHEFN
Sequence: MLVLVSPAKTLDFENPPITNTHTQPCLLKQSQTLIDVCRELTPMDIASLMKVSDKIAGLNAARFADWQPPFTLDNAKQAIFAFRGDVYTGFDADHLSESQMASSQKHLRILSGLYGLLKPLDLIQPYRLEMGTKLTNPQGRNLYAFWGETITAEVNKALKEQGDDIIVNLASNEYFKSVNVKQLEGQLITPVFKDCKKGQFKVISFYAKKARGLMARYIVDTKPTSVEQLTAFDLEGYYYNEAQSTPTAPVFLRDEQK
What are the official names of this protein?
UPF0246 protein Sfri_2896.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: TVP23_SCHPO
Sequence: MFTSLDRNLYVDNHITLTKMDYQNTETIAEQERNASRLPQMFQMSSHPVALFFFLLFRTGAIVAYILGMFFTSSFMLLFIVIFTLLAVDLWTVKNVSGRLLVGLRWRNETGVDGESIWIFESADPSRPRNAVDQKTFWYALYLYPFIWIILGIVAIIRFEFLWLALVAVAIGLTSVNTAAYSRCDKDAKRRWATELADSNSSGFVSRFLSRAFIKRFIG
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein tvp23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RUVA_POLSJ
Sequence: MIGRISGQLAEKNPPEVLVDCNGVGYEVLVPMSTFYNLPGLGEKVSLLTHFVVREDAQILYGFGSATERAAFRQLIKISGVGPRTALSVLSGMSVEELAQAVTHQEAGRIIKVPGIGKKTAERLLLELKGKLGADIGVQVSVSSDSQSDILQALVALGYSDRDAALALKALPKDIGVSDGIKLALKALAK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RUVB_MYCLE
Sequence: MSEDYLDRDVSPALTVGEADIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGATPDHILLSGPPGLGKTSLAMIIAAELGSSLRMTSGPALERAGDLAVMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVIVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPTELEGVLARAAGILGIELGVEAGAEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLSALTRSFGGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGMVARTPRGRVATAQAWTYLCMTPPVGVTGLSQPGLFES
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CUE_ANOGA
Sequence: MKSPCRAAAGWLVLLLSSCCLGYVIATEWAAAVTTDNGILFFDSNWRKISSAAHQYSRISAFAYDEVLGKLYFADLDHPEYRLFALDYDDTDELHKVTKLLPKSAQTAYISGMAFDHLERRLYWTEKGTRSVYYVAIDELLSSTRSAAAAANGTAAAAATAVEATTSAPPPSSSSPVQLVATVQPDHELAGLAIDECRRHLYWTNCYPKTSNIVRAAMNGTVLNVHEEQVYLPKGITVDHYRNRLYWVEKKYGRRYTIESADLEVNDQRTLQTGLDRLPADIAVKNDYIYWTDQENNEIYEMSKEPNAPSRTVYRGEHPSAVILRANLLLEHQRNNPDCRSVVDRILENMQNSKPASVLQQETQQQGQLTVCLNNGTVNHHTNTCLCQPAFGGKLCEIDLCNNYCAQGSCRIGRDNRPRCDCDRRYEGDRCDRNRCDGFCLNGGRCQFSNGTAGRTEEEMGDRTCLCESTGYSGARCENPICGTDYCYNGECYVEEGKRPKCRCKAGYRGERCEEYSCNNYCLNGGHCTLGNETTVPECECGEEFAGQRCEIAVRLCSTYNEDPQWQQYCLGISKTLPLMEPKVTYCKESFNRTVVYTSLCFTVSFALLLAVVLVVSRMMKPPRPRITKKMVVTPMTSRPPTTQCEITIENCCNMNVCETPCFDTKLLKKSKKEDKQFLLEDIEDVGGSYRKLPNCGDGTAERK
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MIC60_YEAS1
Sequence: MLRTTASRKIVLRRGLASINTGTTVASKKASHKFRNTFWTIALSATAFYAGGIIYSQKNDKFGDFFSNNVPFAEDLLETYEHYHDRPTLFLEDSWDGLKAKSNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSLNDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQRTSEVITELNTQYENSKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANEVGLLSITQVKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSSKILSKNEALVQLTFQVDEIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEGKISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPNSGILGQLTAKVFSLFLFTKTGNPSNATDFDSVYARVGDNLRVSNLNDAVEEVVSLKGWPHKVCESWIEDARRKLEVQRLVEILDCEIRTL
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS4_SYNAS
Sequence: MARYKESACRLCRREGLKLFLKGDRCYGEKCAFERRGYAPGEHGQLRRKQPSDYGVQLREKQKLKRMYGLLEKQFRGYFEKADKKKGITGTNLLLYLERRLDNMVYRLGFANSRNEARQLVRHNHFLVNGRKVNIPSFLVNIGDFIEVTEEGRKNNKIIEAMETIVRRGIPQWLELEQENFKGKVKMLPTREELTMPIQEQLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNLJ_SHESR
Sequence: MQDIQLDKRLSELLSQAVTPQNAQPLMQALCQSLNEHNIRYYVDDAPSITDSEYDRLMQRLKQLEAEYPQFVAADSPTQRVGGMALAKFEQITHLKPMLSLDNAFDEADFSAFHKRVSDRVGEVSFCCEPKLDGLAVSILYRNGVLERAATRGDGTVGEDITENVKTIKSIPLKLRGDNYPELVEVRGEAFMPKAAFEALNERARLKDEKLFVNPRNAAAGSLRQLDSKITASRALSFYAYALGVVEPTSHELAKTHYEQLQQLKSWGLPVSSEIKVCDELSQVFAYYQDILTRRADLPFEIDGVVMKVNDIAQQQTLGFVAKSPRWAIAYKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIERLGVMVGDTVIIRRAGDVIPQIVAIVPERRPEDAKAIAFPQHCPVCGSLVERLEGEAVTRCSGGLFCEAQRKEAIKHFASRKALDIDGMGDKIVEQLIDKELVQSPADLFKLTASMMTMLDRMGMKSATNLAQAIEAAKTTTLPRFLYALGIREVGEATAANLATHFGSLEALRVATIEQLIQVEDIGEVVAQHVAHFFAQPHNLEVIDALITAGVNWPTIAAPSADEQPLKGQTWVLTGTLNQLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGEAAGSKLAKAQELGVKVIGEDELLALLANS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CYSH_BACC0
Sequence: MLTYETWEENDVSFSKEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_SHEB8
Sequence: MAATQYYGTGRRKTSTARVFAKAGSGNIVVNQRPLDQYFGRETARMVVRQPLELVEMTDKLDIYVTVKGGGITGQAGAIRHGITRALMQLDEALRPSLRSAGFVTRDARKVERKKVGLRKARRKPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LEPA_ORYLA
Sequence: MDSALVLFAFLFHCLNVATAAPVNPELQEMKSNVIDIAKELSLRLESIIQTSIGPKFSPPSDELNGLSSIMAVLDECTNQISDNFDEAKKIKVDISSLMDSMSEWSDKHCGEQPSTQAENQTSRRFSITESMQAVTRLKHFLLLLQNNSDQLEIC
What is the function of this protein?
May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
What are the official names of this protein?
Leptin-A.
What is the protein family that this protein belongs to?
Belongs to the leptin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTPB_SALTY
Sequence: MNTTAPTGLLQQPRPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTKRTLVLGAIVLAIGYFMTGMSLLNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSLSLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVLLGTVVMIFLCAWLMHNVKIANLVLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMIEAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPFWVVVASPVLAAIYTRLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGELLISALGLAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTLPIYTGVFSKIGLVTLAVTVVMAIMVPWLNRMINTPGTEQ
What is the function of this protein?
Proton-dependent permease that transports di- and tripeptides.
What are the official names of this protein?
Dipeptide and tripeptide permease B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_DESVH
Sequence: MSNELPAVICLVGPTGAGKTAAALHLAERFAGTVINADSRQVYRDFPIITAQPTAEEQAQCPHRLYGFLETEARMSAGVWGDHATAAIDEALAQGRLPLLVGGTGMYVRALLDGIAAIPAIPRDIHVRWQERCAAEGPQRLHAMLCDIDAEYAARIHPNDRQRVTRALEVHEHTGRTFSEWHRSAMPAPRYRALRIGFAATLDALTPRLAHRIDLMLAAGALDEARRARVHCDDPSAPGWSGIGCAETYAHLVGSLDYEAMRHVWLHNTRAYAKRQLTWFRADTRLTWYAPDDVEGIALGVASFLRGGA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL35_BEUC1
Sequence: MPKNKTNSGAKKRFRVTGSGKIMHKRAHQTHKFEERSRSSVRRLSNDAEVSSADRKSIKKLLGK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RLP52_ARATH
Sequence: MTFLPLLFIFFFLTSIPFPAFSQYNDRSTLLNLKRDLGDPLSLRLWNDTSSPCNWPRITCTAGNVTEINFQNQNFTGTVPTTICNFPNLKSLNLSFNYFAGEFPTVLYNCTKLQYLDLSQNLFNGSLPDDINRLAPKLKYLDLAANSFAGDIPKNIGRISKLKVLNLYMSEYDGTFPSEIGDLSELEELQLALNDKFTPVKLPTEFGKLKKLKYMWLEEMNLIGEISAVVFENMTDLKHVDLSVNNLTGRIPDVLFGLKNLTELYLFANDLTGEIPKSISAKNLVHLDLSANNLNGSIPESIGNLTNLELLYLFVNELTGEIPRAIGKLPELKELKLFTNKLTGEIPAEIGFISKLERFEVSENQLTGKLPENLCHGGKLQSVIVYSNNLTGEIPESLGDCETLSSVLLQNNGFSGSVTISNNTRSNNNFTGKIPSFICELHSLILLDLSTNKFNGSIPRCIANLSTLEVLNLGKNHLSGSIPENISTSVKSIDIGHNQLAGKLPRSLVRISSLEVLNVESNKINDTFPFWLDSMQQLQVLVLRSNAFHGSINQNGFSKLRIIDISGNHFNGTLPLDFFVNWTAMFSLGKIEDQYMGTNYMRTNYYSDSIVVMIKGIALEMVRILNTFTTIDFSGNKFEGEIPRSVGLLKELHVLNLSNNGFTGHIPSSMGNLIELESLDVSQNKLSGEIPPELGKLSYLAYMNFSQNQFVGLVPGGTQFQTQPCSSFADNPRLFGLSLERVCVDIHKKTPQQSEMPEPEEDEEEVMNWTAAAIGSIPGISIGLTMGYILVSYKPEWLMNSGRNKRRIKPI
What is the function of this protein?
Required for defense against powdery mildew pathogen.
What are the official names of this protein?
Receptor-like protein 52, AtRLP52.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SEPF_PROM2
Sequence: MSLISRLKAVVAGDEYLDDDFDELDYASEDELNDIDNFKNSPRNKNALANANPFDFMNNNRSSKVVGMPGISNSSSEVSLMEPRSFDEMPQAIQALRERKTVILNLTMMDPDQAQRAVDFIAGGTYAIDGHQERVGESIFLFAPSCVNVTSSSPEEASPSSVPTENTPQYSLGKNTTPEPAWGNSKLSAYS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: G6PI_CAUSK
Sequence: MADLAAAWTRLEAAAKVAGEKRIALMFEAEPGRLAALTLNVAGLHIDLSKQAWDEAGLEAALDLAHAADVEGARTRMFGGEAINSSEGRAVLHTALRAAKDADVRAGGVPVMAEVEAVRVRMKAFTEAVRSGAIKGATGKPFKAILHIGIGGSDLGPRLLWDALRPIKPTIDLRFVANVDGAEFALTTADLDPAETLVIVVSKTFTTQETLANAAAARAWLSAALGEQGANQHLAAISTALDKTAAFGVADDRVFGFWDWVGGRYSLWSSVSLSVAVACGWEAFEGFLQGGAAMDAHFRDAPLEKNAAVLIALAQIFNRNGLDRRARSVVPYSHRLRRLASFLQQLEMESNGKSVGPDGQAVKHGTATVVFGDEGANVQHAYFQCMHQGTDITPLEFVALAQSDEGPAGMHAKLLSNVLAQAEALMVGRTIEDVRTELVAKGVSEAEIATLAPQRAFAGNRPSTMVVLDRLTPQTFGALIALYEHKTFVEGVIWGVNSFDQWGVELGKVMAGRILPELESGAAGRHDPSTAALIERLKL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_PROMS
Sequence: MAATVKKTGSKKSKRNVPNGVVHIQSTFNNTIVSITDTSGHVISWSSAGASGFKGARKGTPFAAQTAAEAAARRALDQGMRQIEVLVRGPGAGRETAIRALQVAGLEITLIRDVTPLPHNGCRRPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LVR_LEIAQ
Sequence: MTATSSPTTRFTDRVVLITGGGSGLGRATAVRLAAEGAKLSLVDVSSEGLEASKAAVLETAPDAEVLTTVADVSDEAQVEAYVTATTERFGRIDGFFNNAGIEGKQNPTESFTAAEFDKVVSINLRGVFLGLEKVLKIMREQGSGMVVNTASVGGIRGIGNQSGYAAAKHGVVGLTRNSAVEYGRYGIRINAIAPGAIWTPMVENSMKQLDPENPRKAAEEFIQVNPSKRYGEAPEIAAVVAFLLSDDASYVNATVVPIDGGQSAAY
What is the function of this protein?
Catalyzes the regio- and stereoselective reversible NAD-dependent reduction of (6R)-2,2,6-trimethyl-1,4-cyclohexanedione (levodione) to (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone (actinol).
What are the official names of this protein?
Levodione reductase, (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ATSE3_PSEAE
Sequence: MNANLPPSAISELHGPRLLLRAWRDSDREAFAEMCADPQVMEFFPSVLDRAQSDALVDRVQAHFAERGYGPWALELPGEAAFIGFTGLFDVTMDVHFAPTVEIGWRLAPAYWGRGLAREAAETALDFAFERLRLPEVVAFTTPPNRRSWGLMERLGMRRDPAEDFDHPLLAADHPMRRHILYRVDAARWAER
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product.  It prefers the peptide Asp-Phe methyl ester (or aspartame) and the peptide antibiotics polymyxin B and colistin.  Other substrates like dopamine, serotonin, puromycin, chloramphenicol, D-glucosamine, glycine and N-alpha-acetyl-L-glutamine are used and displayed lower activity.
What are the official names of this protein?
Acetyltransferase PA3944, GCN5-related N-acetyltransferase, GNAT.
Protein: CD3Z_HUMAN
Sequence: MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPQRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098, PubMed:7509083).  CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme (PubMed:7509083).  Plays an important role in intrathymic T-cell differentiation.  Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN) (By similarity).
What are the official names of this protein?
T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain.
What is the protein family that this protein belongs to?
Belongs to the CD3Z/FCER1G family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KDGL_RHIME
Sequence: MDAKNTTSRNGTAAPVHKHRGIRHLFAAASYSFGGAKRLIGEAAFRHELIAFAVAMVAFMIVGANLFQYVAMAILFLLMMAFEAINTAIEEIVDRVSPEISEMGRNAKDLGSFACLCLILANAAYALYVIFLARFLG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid.  Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
What are the official names of this protein?
Diacylglycerol kinase, DAGK, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the bacterial diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: O161_CONVR
Sequence: MKLTCVLIITVLFLTASQLITADYSRDQRQYRAVRLGDEMRNFKGARDCGGQGEGCYTQPCCPGLRCRGGGTGGGVCQL
What is the function of this protein?
Ion channel inhibitor that inhibits the increase in intracellular calcium upon depolarization in DRG neurons.  In vivo, both intraperitoneal and intracranial injections into mice induce hyperactivity.
What are the official names of this protein?
Conotoxin Vi6.1, Conotoxin vi6a, virgo 1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TGB1_NMV
Sequence: MDCKYLLELLDSYSFIRSSRSFSSPIIIHGVAGCGKSTIIQKIALAFPELLIGSFTPALLDSNSGRKQLAVTSDPLDILDEYLGGPNPVVRLAKFCDPLQYSCEQPEVPHFTSLLTWRFCVRTTALLNGIFGCQIKSRREDLCHLTHENPYTTDPKGVVVAHEQEVINLLLQHGCPVTPTQHLWGLTIPVVSVYITSIASLSTVDRANLFLSLTRDSKALHIFEFDAWSHATC
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Increases plasmodesma size exclusion limit.  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
What are the official names of this protein?
Movement and silencing protein TGBp1, 25 kDa protein, Silencing suppressor P25, Triple gene block 1 protein, TGBp1.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp1 protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PVCA_XENNA
Sequence: MEYFDIEEVSSKILHELLQYRRRFPESEHTIQYEENKVSEVQLPRIRAFVEQGKPIECILPAFPTKSPNPRKVLGKMPDMAEKLSLMFLNSLCQRIQLYYPPGAKIIICSDGHVFSDLIHVDDNTITDYQVEIEKLLHESGATHLSVFNLGNVESLTQYTDDYDQLRELLVKNYASSTEEIKAILKENEEGLLLYRAITRFLYEDSLLPEYTGSKNALQKDARQRSVGVIQRSWAWGNLLAEQFPQAIRLSIHPQSVESLKLGIHMMPTRDDWLTPWHGVAANINGQFVLMKSDEVKNLQGKLIHIRGVPSHYVIETESERNQEIEPIAEAVHAG
What is the function of this protein?
Involved in the biosynthesis of rhabduscin, a tyrosine derivative which is a potent inhibitor of phenoloxidase, a key component of the insect's innate immune system (PubMed:22711807).  Responsible for the synthesis of the isonitrile group on tyrosine using the C2 of ribulose 5-phosphate as the source of the carbon atom (Probable).
What are the official names of this protein?
L-tyrosine isonitrile synthase, Rhabduscin biosynthesis protein PvcA.
What is the protein family that this protein belongs to?
Belongs to the isocyanide synthase family.