PharMolix/UniProtQA huggingface dataset:
Protein: CYC8_YEAST
Sequence: MNPGGEQTIMEQPAQQQQQQQQQQQQQQQQAAVPQQPLDPLTQSTAETWLSIASLAETLGDGDRAAMAYDATLQFNPSSAKALTSLAHLYRSRDMFQRAAELYERALLVNPELSDVWATLGHCYLMLDDLQRAYNAYQQALYHLSNPNVPKLWHGIGILYDRYGSLDYAEEAFAKVLELDPHFEKANEIYFRLGIIYKHQGKWSQALECFRYILPQPPAPLQEWDIWFQLGSVLESMGEWQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQFYDPQKALDYLLKSLEADPSDATTWYHLGRVHMIRTDYTAAYDAFQQAVNRDSRNPIFWCSIGVLYYQISQYRDALDAYTRAIRLNPYISEVWYDLGTLYETCNNQLSDALDAYKQAARLDVNNVHIRERLEALTKQLENPGNINKSNGAPTNASPAPPPVILQPTLQPNDQGNPLNTRISAQSANATASMVQQQHPAQQTPINSSATMYSNGASPQLQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAHAQAQAQAQAQAQAQAQAQAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQPLPRQQLQQKGVSVQMLNPQQGQPYITQPTVIQAHQLQPFSTQAMEHPQSSQLPPQQQQLQSVQHPQQLQGQPQAQAPQPLIQHNVEQNVLPQKRYMEGAIHTLVDAAVSSSTHTENNTKSPRQPTHAIPTQAPATGITNAEPQVKKQKLNSPNSNINKLVNTATSIEENAKSEVSNQSPAVVESNTNNTSQEEKPVKANSIPSVIGAQEPPQEASPAEEATKAASVSPSTKPLNTEPESSSVQPTVSSESSTTKANDQSTAETIELSTATVPAEASPVEDEVRQHSKEENGTTEASAPSTEEAEPAASRDAEKQQDETAATTITVIKPTLETMETVKEEAKMREEEQTSQEKSPQENTLPRENVVRQVEEDENYDD
What is the function of this protein?
Acts as component of the CYC8-TUP1 corepressor complex which is involved in the repression of many genes in a wide variety of physiological processes including heme-regulated and catabolite repressed genes.  May also be involved in the derepression of at least some target genes.  The complex is recruited to target genes by interaction with DNA-bound transcriptional repressors, like MATALPHA2, MIG1, RFX1 and SKO1.  The complex recruits histone deacetylases to produce a repressive chromatin structure, interacts with hypoacetylated N-terminal tails of histones H3 and H4 that have been programmed for repression by the action of histone deacetylases and interferes directly with the transcriptional machinery by associating with the RNA polymerase II mediator complex.
What are the official names of this protein?
General transcriptional corepressor CYC8, Glucose repression mediator protein CYC8.
What is the protein family that this protein belongs to?
Belongs to the CYC8/SSN6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL34_NITSB
Sequence: MKRTYQPHNTRRKRTHGFRARMKTKNGRKVINARRRKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SSRP1_DROPS
Sequence: MTDSLEYNDINAEVRGVLSSGRLKLTDQNIIFKNNKTGKVEQISVDDIDLINSQKFVGTWGLRVFTKSGALHRFTGFRDSEHEKLGKFIKDAYSQEMVEKEMCVKGWNWGTARFMGSVLSFDKDSKTIFEVPLSHVSQCVTGKNEVTLEYHQNDDAPVGLLEMRFHIPAVESADDDPVEKFHQNVMSKASVISASGESIAIFREIQILTPRGRYDIKIFSTFFQLHGKTFDYKIPMDSVLRLFMLPHKDSRQMFFVLSLDPPIKQGQTRYHYLVLLFAPDEETTIELPFSEAELRDKYEGKLEKELSGPVYEVMGKVMKVLIGRKITGPGNFIGHSGTAAVGCSFKAAAGYLYPLERGFIYIHKPPLHIRFEEISSVNFARSGGSTRSFDFEVTLKNGTVHIFSSIEKEEYAKLFDFITQKKLHVSNMGKDKSGYKDVDFGDSDNENEPDAYLARLKAEAREKEEEDDDGDDSDEESTDEDFKPNENESDVAEEYDSNVEDDSDDDSDASGGGGDGGTDGSTKKKHKEKKNEKKEKTHKEKEKIKKPTKKKDTGKPKRGTSAFMLWLNDTRESIKRENPGIKVTEIAKKGGEMWKELKDKSKWEEAANKDKIRYQEEMRNYKSGAGGGSEDEKGGTSKATKKRKSEPSPSKKANTSGSGFKSKEYISDDESTSDDQEKVKEIPKKKNKSTAEDKDKNSKKSESEGGDSDDASNASEDDDEEEDEGSD
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  Binds specifically to single-stranded DNA and RNA with highest affinity for nucleotides G and U.  The FACT complex is required for expression of Hox genes (By similarity).
What are the official names of this protein?
FACT complex subunit Ssrp1, Facilitates chromatin transcription complex subunit Ssrp1, Recombination signal sequence recognition protein, Single-strand recognition protein.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus, nucleolus. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: EIF3J_DROPS
Sequence: MADDWESAADSEIILQNAASTVNKWEGEDDDDDVKESWEDEEEKKDEENEKPTITDVPVKTKPSKALKAKLEEQARLEEEKEAKRLASLTPEEKLAEKLRLQKIQEDSDLNHALDTFGVTRAETNGNGLDSFNPETKEQFKEFGSALSWKVGQYRESAEFPQFVEDLVRGLCIHLSAADIKKVKMSVEILHSEKLKMEKAIAKKAAGKNKGKATLRTESDDIDDYKKYGNDFSEDYDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CALS8
Sequence: MDLFNFDAIKISLASPEKIREWSRGEVKKPETINYRTLKPEKDGLFCEKIFGPTKDWECHCGKYKKVKYKGVVCDKCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGVPSRMGLILDMTPRNLEKVLYFAAYVVIDPGDVPNLEKKQILSEKEYRELKEKYGDRFRAGMGAEAIKELLKEIDLDKLSQELRQELETATGQKKLKIIKRLEVVEAFRKSGNRPEWMILDVIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLMELGAPDIIIRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKIYQCGLPKEMALELFKPFVMKKLVEKGICNNIKNAKKAVERQRSEVWDILEEVIKDHPVLLNRAPTLHRLGIQAFEPVLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARFLMLSANNLLKPADGKPIVVPTQDMVLGIYYLTLEKKGDKGEGKIFSSEDEALLAYEHKVVGLHARIKVRRTIEKDGEVVSGIVETTPGKIILNQVIPQDLGFVDRSKKENLLKYEIDTLVDKKMLGKIIDRCIKVYGTTRTAEILDEIKELGFRFSTRGAITISVSDMVIPEVKQKLIAEAEQKVENIEKLYRHGLISDEERYEQVISIWNETKDKLTEELIQNLDEFNPIFMMASSGARGSKNQISQLAGMRGLMANPSGKTIEMPIKSNFREGLNVIEFFISTHGARKGLADTALRTADSGYLTRRLVDVAQDIIVREEDCGTEKGIEVSEIRDGTEVIETLEERIIGRYAAKDIINEKTGEVIVKRNELITEEIAKKIVDAGEKSVYVRSVLECKTRYGVCTKCYGLDLGTGQPVNVGEAVGIIAAQAIGEPGTQLTMRTFHTGGIAGQDITQGLPRVEELFEARKPKGVAIISEIEGYVSIKEDKKRTITVRNDNGEERTYEVPYGARLKVNDGDYVKAGDELTEGSINPHDLLRIKGPRGVQSYLLAEVQKVYKMQGVDINDKHIEIIIRQMMKKVKIEDPGDTELLPGDIVEIYRFEEENDRAIAEGKRPALGRRVLLGITKAALSTESFLSAASFQETTRVLTDAAIKGKVDPLIGLKENVIIGKLIPAGTGMAKYRNIIVEEKA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RAD18_ASHGO
Sequence: MSIQPGQVVTDPSDFAGTTIPELADLDSLLRCHICKDMLQTPVLTQCGHTFCSLCIREYLNKESRCPLCLAELRQNMLQKEFLVGELAACYMELRARLLETVRIPPKKVAEVVQNNSPIELDSDGEVEIIESCTGAVPGSKRGSPQVEEVEAAAKRQRTKQNGIQYMLQKKPKAVGEKVPCPICNRLYNKEFLERVHLDECLMMGTLRESGESDITVIEQQSYTAEPDSKNSHVAERRGESPVDEVVTHKESYLGSGLRVTKSRLPKLHFTSLSTSQLKQKLSELGLPTAGSRQQMINRYNHYELLWNSNFLDSIQPVGEGELRRSLLSWEATRNTDTPISSGVSSSITNMLKTNNSASTLLKSFKTDKFDKSAWSRLHGKEFRRLIRAAKKSMLEQDRGEAITAQNNELSTKASVDMESTSFRNDTNDTIDTVTDEVHEDLK
What is the function of this protein?
E3 RING-finger protein, member of the UBC2/RAD6 epistasis group.  Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
What are the official names of this protein?
Postreplication repair E3 ubiquitin-protein ligase RAD18, RING-type E3 ubiquitin transferase RAD18.
What is the protein family that this protein belongs to?
Belongs to the RAD18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRP1_SORBI
Sequence: NSLHSAFSTYGEVLESKIILDRETQRSRGFGFVTFSTEEAMRSAIEGMNGKELDGRNITVNEAQSRGGRGGGGGGGYGGGRGGGGGYGRRDGGGGGYGGGGGGYGGGRGGYGGGGYGGGGGGYGGGSRGGGGYGNSDGNWRN
What is the function of this protein?
Possibly has a role in RNA transcription or processing during stress.
What are the official names of this protein?
Glycine-rich RNA-binding protein 1.
Protein: URE1_MAGMM
Sequence: MAYTLDRGSYAAMFGPTVGDRVRLADTELIIEVEQDYTTYGEEVKFGGGKVIRDGMGQSQHSRQEGAVDTVITNALIVDHWGIVKADVGIKDGRICAIGKAGNPDVQPNVDIIIGPGTEAIAGEGRILTAGGIDAHIHWICPQQIEDALHSGITTMLGGGTGPAEGTNATTCTPGPWHIARMLQAAEGLPMNMGFFGKGNASRPQGLEEQLRAGACGLKLHEDWGTTPSAIDVCLSVAEKWDVQVAIHTDTLNESGFVENTTAAFKGRTIHAFHTEGAGGGHAPDIIKLCGEANVLPSSTNPTRPFTRNTLDEHLDMLMVCHHLDSRIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTADKMKRQRGALPEERGQNDNQRVKRYIAKYTINPAITHGIAHYVGSVAVGKLADLVLWKPMFFGVKPDLVLKCGTIASAAMGDPNASIPTPQPVHYRPMFGAFGGALTHSAVNFVSQAGLDGEIAQQFGLRKTLLPVVGCRTIGKADMVHNSATPHMEVDPETYEVRADGRLLTCEPATVLPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCPB_TRIRU
Sequence: MVAYRFLTLISLGLGSHCVSALQYGYNQLSTHKDPAVVAGAFPAINGTHLRSPAFTSPGTVSRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEAGFKSEEGRKFPYMYLSASSSSVENPSSRKLRVWLQGGVHGNEPAGDQSMLVLLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHLKLARQQTRDIKELFAKFSPHIATDMHEFTAGRAFGPKKDFIYAADALFSAAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITLGESSSSKLLLREAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMAKSVLQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDKSPIIERTFGMLNTTDASLFDYPIDFATTTPAEPVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEFYEGVVTTTVETKLVERSIRLPPGSYLVKTNQKNAALAFVALEPENIDSFASFGIIPVNTGDQYPIFRLK
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Carboxypeptidase 2, Carboxypeptidase M14B, Carboxypeptidase MCPB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL73_ARATH
Sequence: MAESKVVVPESVLKKIKRQEEWALAKKDEAVAAKKKSVEARKLIFKRAEQYAKEYAEKDNELIRLKREAKLKGGFYVDPEAKLLFIIRIRGINAIDPKTKKILQLLRLRQIFNGVFLKVNKATVNMLRRVEPYVTYGYPNLKSVKELIYKRGYGKLNHQRIALTDNSIVDQALGKHGIICVEDLIHEIMTVGPHFKEANNFLWPFQLKAPLGGLKKKRNHYVEGGDAGNRENFINELVRRMN
What are the official names of this protein?
60S ribosomal protein L7-3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RECF_STRPG
Sequence: MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIYFLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQAKLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQRNSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESLSLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFASQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQTFITTTSLDHLSQLPEGIHIFHVTKGTVQIDSDIH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPA_STAA8
Sequence: MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQDGYKSLEEGQAVEFEVVEGDRGPQAANVVKL
What is the function of this protein?
Involved in cold stress response and in the susceptibility to an antimicrobial peptide of human cathepsin G (CG117-136).  Regulates yellowish-orange pigment production through a still unclear SigB-dependent mechanism.
What are the official names of this protein?
Cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMNA3_HUMAN
Sequence: MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDLAASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLRSPPQMEGPDHGKALFSTPAAVPELKLLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMHQHNIHLAKEPVQNEISATYIRRALGQGQSVKYLIPDAVITYIKDHGLYTKGSTWKGKSTQSTEGKTS
What is the function of this protein?
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP.  Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency.  Can use triazofurin monophosphate (TrMP) as substrate.  Can also use GTP and ITP as nucleotide donors.  Also catalyzes the reverse reaction, i. e.  the pyrophosphorolytic cleavage of NAD(+).  For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates.  Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+).  Protects against axonal degeneration following injury.
What are the official names of this protein?
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3, NMN/NaMN adenylyltransferase 3, Nicotinamide-nucleotide adenylyltransferase 3, NMN adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, NaMN adenylyltransferase 3, Pyridine nucleotide adenylyltransferase 3, PNAT-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNME_CHLTB
Sequence: MLRNDTITAIATPPGEGSIAIVRVSGPDAISISDRIFSGNIAGYASHTAHLGTVSHNAVCIDQALVLVMRAPRSFTGEDIVEFQCHGGYFACSQIVNALLAEGARAALPGEFSQRAFLNGKIDLIQAEAIQQLIAADNIDAFRIAQNQFQGHTSQAISSISSLIIEALAYIEVLADFPEEDIETEDSLPKHRIMEALSITDELLSSFDEGQRLAQGTSIVLAGLPNAGKSSILNALTQKNRAIVTDIPGTTRDILEENWVLQGKNLRLIDSAGLRETENLVEKEGIARAREAMSQAEGILWVVDASQPLPEFPTILYQKPTILLWNKCDIVSPPQIEVPFQQISVSAKTGEGLLELKQALQKWLNTTQLGKSSKIFLVSARHHSLLHSVYTCLTAALNGFTEHLPNECIALDLRQALHSIGNLSGSEVTENVLGEIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTUA_NICSY
Sequence: MASISAATATSSTKLVSSNSTNPLLPSSTKPSKLILSSSFTPNCSTLFLHSPATPSSTATHRHRRFTVRAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALASMGNSAPKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSGADGPMPQTKEHILLAKQVGVPNMVVFLNKQDQVDDEELLQLVELEVRELLSSYEFPGDDIPIISGSALLALEALMANPSIKRGENQWVDKIYELMDAVDSYIPIPVRQTELPFLMAIEDVFSITGRGTVATGRVERGTVRIGDTVDIVGLKDTRSTTVTGVEMFQKILDEAMAGDNVGLLLRGIQKIDIQRGMVLAKPGTITPHTKFEAIVYVLKKEEGGRHSPFFSGYRPQFYMRTTDVTGKVTSITTDKGEESKMVMPGDRVNLVVELIMPVACEQGMRFAIREGGKTVGAGVIQKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor TuA, chloroplastic, EF-TuA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: M1_I03A0
Sequence: MSLLTEVETYVLSIIPSGPLKAEIAQKLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMATITNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVANQARQMVQAMRTIGTHPNSSAGLRDNLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: UPPP_NOSS1
Sequence: MSIFKRQWFVLISAVSAALSVVLFPLEVFSASPNSGGGGVQQMNILQAIVLGFVQGMTEFLPISSTAHLKVVPVALGWGDPGVAFTAIIQLGSIAAVLWYFWGDLTRIIKGATRAIALKDYADYDLRLSLGIVLGTIPIVFFGLLIKTFIPDYDSSPIRSLGAIAVASIVMSLLLGVGEKLGKRERDFEHLTMQDGLLMGLAQALTLIPGVSRSGSTLTSGLFMGLQRETAARFSFLLGIPAITLAGLVELKDLLAEGIADGAALPLIMGVISAAIFSYLAIAGLLSFLKTQSTWVFIWYRLVFGVAILGAISAGILQNS
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INSI1_ECOLI
Sequence: MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDTGGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRRYYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQKTLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPIHERSRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIIVRLRGKDSVSVNQALTDKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIRQYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Transposase InsI for insertion sequence element IS30A.
What is the protein family that this protein belongs to?
Belongs to the transposase IS30 family.
Protein: STF0_MYCTU
Sequence: MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
What is the function of this protein?
Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).  The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid and the most abundant sulfated metabolite found in Mycobacterium tuberculosis, that is a potential virulence factor thought to mediate host-pathogen interactions.
What are the official names of this protein?
Trehalose 2-sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the Stf0 sulfotransferase family.
Protein: PA2B_MICCO
Sequence: MNPAHLLVLAAVCVSLLGASSVPPRPLNLINFQRMIQCTTRRSAWDFTNYGCYCGAGGSGTPVDELDRCCKVHDDCYGAAEKYHRCSPKLTLYTSTCSSQTGSVTCKDNGTKCKAFVCNCDRTAALCFGRAPYNKNNENINPNRCR
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIC_SALPA
Sequence: MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANNGETIDIDLKQINSQTLGLDTLNVQKKYDVKSEAVTPSATLSTTALDGAGLKTGTGSTTDTGSIKDGKVYYNSTSKNYYVEVEFTDATDQTNKGGFYKVNVADDGAVTMTAATTKEATTPTGITEVTQVQKPVAAPAAIQAQLTAAHVTGADTAEMVKMSYTDKNGKTIDGGFGVKVGADIYAATKNKDGSFSINTTEYTDKDGNTKTALNQLGGADGKTEVVSIDGKTYNASKAAGHNFKAQPELAEAAAATTENPLAKIDAALAQVDALRSDLGAVQNRFNSAITNLGNTVNNLSSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Phase 1-A flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: UBIG_SHEHH
Sequence: MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGCGGGILSESMAKIGAQVTGLDMGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDVVTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIRAYVETILGAEYLLKMLPVGTHDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: HSLU_SALAR
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLVPPAKNNWGQTEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSLFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_YARLI
Sequence: MPAPVNIPSMFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIAELPWKPKGVILSGGPYSVYAEGSPHVDHAVFDLGVPILGICYGMQELAWINGKGVHAGEKKEFGHATIHVEKPSDPLFHGIDNFQVWMSHGDKLNALPTGYEVVATSDNSPYAGIAHTSEKIWGIQFHPEVTHTTKGKQLLQNFAVDICGAAQKWSMENFVDTEIQRIRDLVGPHAEVIGAVSGGVDSTVGAKLMKEAIGDRFHAILVDNGVMRLNECENVKKTLGEGLGINLNVVDAADLFLGKLKGVTDPEKKRKIIGNTFIEVFEEEAAKIQPTHPEAGEIEFLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLDNMKLKLIEPLRELFKDEVRKLGEIMGIPHDLVWRHPFPGPGIAIRVLGEVTPSQVEIARKADFIYIEEIKKAGIYEEISQAFACLLPVKSVGVMGDQRTYEQVIALRAIETVDFMTADWYIFDANFLKTVARRIVNEVPGVARVVYDITSKPPATVEWE
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_THEAC
Sequence: MNVFNTASDEDIKKGLASDVYFERTISAIGDKCNDLRVAMEATVSGPLDTWINFTGLDEVLKLLEGLDVDLYAIPEGTILFPRDANGLPVPFIRVEGRYCDFGMYETAILGFICQASGISTKASKVRLAAGDSPFFSFGIRRMHPAISPMIDRSAYIGGADGVSGILGAKLIDQDPVGTMPHALSIMLGDEEAWKLTLENTKNGQKSVLLIDTYMDEKFAAIKIAEMFDKVDYIRLDTPSSRRGNFEALIREVRWELALRGRSDIKIMVSGGLDENTVKKLREAGAEAFGVGTSISSAKPFDFAMDIVEVNGKPETKRGKMSGRKNVLRCTSCHRIEVVPANVQEKTCICGGSMQNLLVKYLSHGKRTSEYPRPKEIRSRSMKELEYFKDIS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Putative nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family. Highly divergent.