PharMolix/UniProtQA huggingface dataset:
Protein: PANB_DEHM1
Sequence: MRTTISQLKEMKQNKQKIAMLTAYDYPTAQILDKAGIPAILVGDSLGMVVLGYDSTVSVTMEDMLHHLKAVVRGSQKAMVIADMPFMTYHLSPEQALLNAGRFMQEGGAQAVKLEGGVNVADKVKRIVDCGIPVMGHIGLTPQSVNQLSGFKVQGKTLTAALALLEDARALEKAGAFAIVLETMPAELAAMITAAVSIPTIGIGAGENCDGQVQVVSDMLGMFTDFVPKHTKKYADLNGIISKAVSGYVTEVAKGEFPTLKESFTLDKKVLEELKKCVSSEQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_PELUB
Sequence: MEIQIIRCLQDNYSYLIVDKAKNIACVIDPSEAKPVIKYLEDKNIHLKYILNTHHHYDHVGGNKELKEKYGASVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICFYFYNEESVFTGDTLFSLGCGKIFEGTYSQMYNSLMKIKALPEKTKIYCGHEYTKQNSKFCIAHDQDNENLKVKIKLIDEKLEKNLPTIPSTIKEELECNIFLRSGTEENFSKLRDLKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CD1B_HUMAN
Sequence: MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
What is the function of this protein?
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD1b.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Protein: HIS2_BRUAB
Sequence: MSQFTLADLERIVAERASVTDGTSYTASLVAKGQPKAAQKLGEEAVETVIAAVSGDRAGVVSESADLLYHLAVVWNIAGVALEDVLQELQRRTAQTGLAEKASRPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRF_STAAM
Sequence: MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILDKITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIPSLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGQFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge.  LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase, Multiple peptide resistance factor.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SODC_CARPA
Sequence: MVKAVAVLSSSEGVSGTIFFTQAADGPTTVTGEISGLKPGHHGFHVHALGDTTNGCMSTGPHFNPAGKEHGAPEDDIRHAGDLGNVNVGDDGKVSFSIIDSQIPLTGPNSIVGRAVVVHADPDDLGKGGHELSKTTGNAGGRVACGVIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ANAPZ
Sequence: MADHWNKLTRPSSIKVVGGKEPCVMELVIEPLESGFALTLGNALRRVMMSSLRGFAVYGIEIEGASHELTALSGVREDVADLVLNLSMLRVKLLNSNQRVLRLVARGPGEVTAASIVDSADHVVLNKDLHICTLGKDVDFCMKIYVNSGKGYVPATEYRAASRSGGASEVGSGFIATNALYSPVKKVALKIESSRIGQFTDYDRLMLTVETDGSVAPDDAVAVAAKILQDQLQSFISFDEVEETRKSVDKEEGVLPYDHNLLRKVDELELSVRSHNCLKNDNITYIGDLVQRTESDMLRTPNFGRKSLNEINEVLASMNLHLGMKVPNWPPESIENLSKQYSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ILVC_ECOLU
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RSMH_BURP6
Sequence: MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_PYRTR
Sequence: MVLQAIKYSRGQLEILDQLKLPHAEEYDHIYSSTDAWHAIKEMRTRGAPAIAIVAALALAVELSNMKLPSVAEEVKVFITEKLDYLVTSRPTAVNLADAAGKLQRITESAAASEGADGDSVREAYVSAAEKMLVDDVSDNESIGKHGAEWIMKNTEAGKKGPVSMMTHCNTGSLATAGYGTALGVIRSLHSAGSLKHAFCSETRPYNQGSRLTAFELVHDKIPATLITDSMAAALLRLRGESENIAGIVVGADRVAANGDTANKIGTYSLAILAKHHGVKFLVAAPRTTIDLKTKSGADIVIEERSGKEVTLVKGPRHDGVTLDLGVIETISIAANGIGVWNPAFDVTPAELIDGIITEVGVVEKDSNGVFHLDTVFKAEGSEVKPSTIGGL
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2319_MYCTU
Sequence: MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLADGIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYRCYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRINGVVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG
What are the official names of this protein?
Universal stress protein Rv2319c, USP Rv2319c.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: RS17_RALPJ
Sequence: MTEAATSLKRTLVGRVVSNKMDKTVTVLIENRVKHPLYGKYVVRSKKYHAHDEANQYNEGDKVEITESRPLSRTKSWVVSRLLEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL11_RHOP5
Sequence: MAKKVTGYLKLQVPAGAANPSPPIGPALGQRGLNIMEFCKNFNAQTQKEEKNTPIPVVITIYADRSFTFEMKTPPMSFFLKQAAKIQSGSKLPGRDVAGKVSSAQVREIAERKMKDLNCDSIESAMRMVEGSARSMGLQVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: KDPA_STAAU
Sequence: ALSMMLIPGSLVFLFGRMLKTKLQIHPHAIMIFVAMFVMFIGFLVTCLYFEFAGNPVLHHLGIAGGNMEGKETRFGIGLSALFTTITTAFTTGTVNNMHDSLTPLGGMVPMVLMMLNAVFGGEGVGLMNMLIYVMLTVFICSLMIGKTPSYLGMKIEGKEMKLIALSFLVHPLLILVFSALAFIVPGASDALTNPQFHGVSQVLYEFTSSSANNGSGFEGLGDNTVFWNISTGIVMLLARYIPIVLQILIVSSLVNKKTYQQHTQDVPINNLFFSSVLIIFIILLSGLTFLPDLMLGPIGEQLLLHA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYS_STAMF
Sequence: MSWSILKLLREKPEELKEHVKKRFMDPSIVDEAYKTDLEWRRTLTYIQELRHKHNVVSREIPKLKGVDKEKKIKEAKQLLKELEEVEKKLKELEEKRQKLLFSLPNIVHETVPVGPDDTYNVPIRFWGKPRVWKGFIDQFKEQTEKYGFKVEYEVIDWKPVGHADMLEKVLRLGDTFKAGQVAGSRFYYLFNDIVFLDMALLAYAIDYLTSKGYTLVLPPYMLRHKVMMGVIDMDTFKDAIYKIEGEDLYLIATAEHPLAALHAWEDIPEEELPLKYVGISPCFRKEAGAGNRDLKGIFRVHQFHKVEQFVYAKPEDSWDIMEELISNAEHLFRGLGIPYRIVNIASGDLGAPAAKKYDLEAWMPAQGRYREMVSCSNVTDWQAFRLRIRLIRRKGMVKEYLHTLNSTAIASTRTITAILENFQEPDGTVIVPKVLRKYLEVFKSAPIDAIHPVKKEKN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_CHLCH
Sequence: MNKLVIQGGRPLSGTLTASGSKNTSLPIIAATLLHGGGTFTLHRIPNLQDIDTFRQLLHHLGAESSLENNTLTISTANVNSILAPYELVKKMRASIYVLGPLLARFGHARVSLPGGCAFGPRPIDLHLMVMEKLGATITIETGFIDAVAKEGKLRGAHIHFPISSVGATGNALMAAVLAEGTTTLTNAAAEPEIETLCNFLIAMGATIRGVGTTELEIEGTSSLHAVTFNNVFDRIEAGTLLAAAAITGGDITLLEANPRHMKSVLKKFAEAGCTIETTPDSITLKSPETLLPVDVTAKPYPSFPTDMQAQWIALMTQANGTSRITDKVYHERFNHIPELNRLGAGIEIHKNQAIVHGIRKLSGGPVMSTDLRASACLVLAGLVAEGTTEVLRVYHLDRGYENIEMKLRTLGASIERQKYQEF
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB41_ARATH
Sequence: MGRSPCCDKNGVKKGPWTAEEDQKLIDYIRFHGPGNWRTLPKNAGLHRCGKSCRLRWTNYLRPDIKRGRFSFEEEETIIQLHSVMGNKWSAIAARLPGRTDNEIKNHWNTHIRKRLVRSGIDPVTHSPRLDLLDLSSLLSALFNQPNFSAVATHASSLLNPDVLRLASLLLPLQNPNPVYPSNLDQNLQTPNTSSESSQPQAETSTVPTNYETSSLEPMNARLDDVGLADVLPPLSESFDLDSLMSTPMSSPRQNSIEAETNSSTFFDFGIPEDFILDDFMF
What is the function of this protein?
Transcription factor involved in salt stress response.  Confers tolerance to salt stress (PubMed:22575450).  Involved in distinct cellular processes in response to osmotic stress, including control of primary metabolism and negative regulation of short-term transcriptional responses to osmotic stress (PubMed:19211694).  Can activate the steps necessary for aliphatic suberin synthesis and deposition of cell wall-associated suberin-like lamellae.  Involved in the production of aliphatic suberin under abiotic stress conditions (PubMed:25060192).
What are the official names of this protein?
Transcription factor MYB41, Myb-related protein 41, AtMYB41.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROBF_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEESVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PSTB_BRUA2
Sequence: MNLMAERSLENAVGEKMNATASSIKMRGEKVCVFYGEKQALFDVDLDIPEKMVTALIGPSGCGKSTFLRSLNRMNDTIEGCRIAGRITLDNEDIYDPRLDVVELRARVGMVFQKPNPFPKSIYENVAYGPRIHGLARSKAELEEIVVTSLQKASLFEEVKDRLHDAGTGLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATAKVEELIDELRQNFTIVIVTHSMQQAARVSQRTAMFHLGNLVEVGDTEMMFTAPTEKRTQDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PAHO_RABIT
Sequence: APPEPVYPGDDATPEQMAEYVADLRRYINMLTRPRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_PSECP
Sequence: MIPENTGPAAVIVLAAGAGTRMKSRTPKILHEIGGRSMVGHALLAARSIEPRQLAIVVRHERDLVAGHVAELDPSAAIVDQDEVPGTGRAVEVALQALDAKEELTGTVVVTYGDVPLLSGGLLAELVATHEREANAVTVLTAVLDDATGYGRILRGEDGTVTGIREHKDSTDEERLIREVNSGIYAFDAAVLREALGKVTTDNAQGEKYLTDVLGLAREAGGRVAAVVTADRWQVEGANDRVQLAALGAELNRRTVEAWMRAGVTVVDPSTTWIDSSVTLDEDVRLLPNTQLHGSTSVARDAVVGPDTTLTDVEVGEGATVIRTHGSGSVIGPRAAVGPFTYLRPGTVLGEKGKIGAFYETKNVTIGRGSKLSHLGYAGDAEIGEDTNIGCGNITANYDGEKKHRTVIGSGVRTGSNTVFVAPVTVGDGAYSGAGAVIRKDVPAGALALSIAAQRNTEGWVPANRPGSRSAELAQAAINNSSSTPASTEEGK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPX_STRPN
Sequence: MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRKQELKEARMRAGIS
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_FRATW
Sequence: MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLSGREVLAGYNVSALIKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MYCMM
Sequence: MATIVDPRDIILAPVISEKSYALLDDNVYTFVVHPDSNKTQIKIAIEKIFAVKVASVNTANRQGKRKRTRTGYGKRKSTKRAIVTLAPGSKPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NU2M_POTFL
Sequence: MKPPILIIIASTIISGTIVVMMSTHWLMTWIGFEMNMLAVIPILMKNFTPRSMEAATKYFLAQATASMILMLGIITNLLLTGQWTMLNNQNQIASNMMTIALTMKLGLSPFHFWVPEVTQGVSLSSGMILLTWQKIAPLSVLHQISPSINPNLLAIAAIASILVGGWGGLNQTQLRKILAYSSIAHMGWMAAVTTYNPDLMTLNLMMYIVMTLSTFMLFMYSSSTTTLSLSHAWNKFPLITSLILMLMMSLGGLPPLSGFIPKWMIVQELTKNDMIIMPTLMAMMALLSLFFYMRLTYATALTLFPTTNNMKMKWQFESTKKMILLSPAIVISTMMLPLTPMMSILN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS8_CAMFF
Sequence: MKFNSHIENLPIYEAGKPIELVIREFGIDQNDIIKLASNENPLGTSKKVIEKIKNVAQNSSLYPDDSYYELKDGLSNLYKVEPKNVIIGSGSDQIIEFALHAKANEKKGILVSGVTFAMYEIYAKHVGAKIYKTKSKEHNLAEFREIYRTNKNDISVIFLCLPNNPLGECLDADEVFSFIKDVSEDTLVVIDGAYMEFAKFKSSKKEIDPKTLIQTFSNALYLGTFSKAYGLGGMRVGYGIANEEIIKALHRLRAPFNITTLSLAAAIEALKDNDFLKETLENNFKEMKVYEEFAKENSIEFIESYTNFITFIFDQHQNATKICDNLLKQGIILRNLKSYSMNAIRITIGKNEQNRRVLDMLKKEI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RUVC_BRUA2
Sequence: MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NDK_YERPA
Sequence: MALERTFSIIKPNAVANNDIGAIYARFERAGFKIIAAKMLHLTKEQAEGFYAEHKGRPFFDGLVEFMTSGPIMVQVLEGENAVQRHRDIMGATNPDNALAGTLRADFSDSFTANAVHGSDAVESAQREIAYFFAADEIFPRS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL361_CLAMS
Sequence: MKVNPSVKRICEKCKVIRRNGRVRVICENPRHKQVQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.