PharMolix/UniProtQA huggingface dataset:
Protein: NU2M_STRPU
Sequence: MRQIVSTFLFVTVVSGTIIVVSSENWFIIWVGLELSTLALVPILCSGFSPRNVEADNKYFLVQASSAALLLNGALGQAWLTGSWSILDPVNEVTSICLSIALAFKIGLAPVHFWFPDVLQGLPFFQGLIIATWQKIAPLILMFYFSQLGFSYLLITPSLISVLIGGWGGLNQTQVRKILAFSSIGNMGWLVITSAYSFNAAIIMLVIYLIINTSLFLLFDHLKVSTLGHLNTISQLSPISVALVLLVMLSLGGLPPLTGFILKFTSLYFLVANNFIILSSIMIIGNLQDYFFYLRISFNTSLFLFPQHIISSASWRNSTIISPLAPKAWLSSVSTVLSTLAIPLTLPLYIIT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NA23_HETCR
Sequence: GNCKCDDEGPYVRTAPLTGYVDLGYCNEGWEKCASYYSPIAECCRKKK
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process.  Specifically inhibits mammalian Nav1. 2/SCN3A (low inhibition) and Nav1. 6/SCN8A sodium channels, as well as insect BgNav1 and VdNav1 sodium channels.
What are the official names of this protein?
Delta-stichotoxin-Hcr1a, Delta-SHTX-Hcr1a, Neurotoxin III, RTX-III, Rm3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RL1_SULNB
Sequence: MAKKLSKRREALLKKVDATKEYSVDEAMATLKELKSAKFDETVEVALNLNVDPRHADQMVRGSVVLPHGTGKTVRVAVFAKDAKADEAKAAGADLVGAADLIEDIQAGKIDFDIVISTPDMMGVLGKVARVLGPKGLMPNPKTGTVTMDVAKAVENAKGGQVNFRVDKKGNIHAGIGKISFDADKIKENFVTLLEKINRAKPASAKGRYITNAAVSLTMSPSITLDTSEVMEIK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: OTSA_SINFN
Sequence: MSRLVIVSNRVPVPDKGGIAPAGGLAVALKVALEEQGGGIWMGWSGKSSGEDEPAPLAQLQQGNITYALTDLTDTDVEEYYHGFANRVLWPICHYRLDLAEYGRKEMAGYFRVNRFFAHRLAPLVKPDDVIWVHDYPLIPLAAELRQMGLENRIGFFLHIPWPPADVLFTMPVHEEIMRGLSHYDVVGFQTDHDLENFASCLRREGIGDALGGGRLSAYGRIFKGGVYAIGIETAAFAEFAKKASTNSTVKKARESIERRSLIIGVDRLDYSKGLTQRIEAFERFILANPAQRGRVTYLQITPKSRSEVPEYEAMQRTVAEQAGRVNGALGAVDWVPMRYINRSVGRRVLAGLYRLGKVGLVTPLRDGKNLVAKEYVAAQDPDDPGVLVLSRFAGAARELQGALLVNPYDIEGTANAMARSLSMPLEERQERWTTMMDQLLEHDVSRWCRDFLNDLTASSDRCG
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: G6PI_FRATM
Sequence: MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGALIALYEHKIFVQGVLWEINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHMD_ECOHS
Sequence: MENIMTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATPMSKYRDYEQSRQSFGINVLGTLVVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLSATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFWLMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYEGYRELKRNAPVGMMVTSGEHHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRDCNLKRPYSH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: PUR7_AROAE
Sequence: MAQPLFESTIKSLPLLGRGKVRDIYAVDADKLLIVTSDRLSAFDVILPDPIPDKGRVLTAMAAFWFARLGHIVPNQLTGIDPESVVASDERDQVRGRSLVVKRLKPLPIEAVVRGYVIGSGWKDYQDTGAICGIRLPAGLAQAAKLPSPIFTPASKADVGDHDENISFAAAQTRCAAELTGLLAGSGTNGARLATEARDAAITLYVEAANYAAGRGIIIADTKFEFGIDSAGTLHLIDEALTPDSSRFWPADSYREGISPPSYDKQYVRDYLETLTWGKKAPGPHLPADVIAKTAAKYREAFERLTGQSLA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: LEU1_BURL3
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMKVDVIEAGFAASSNGDFDAIHTIAGLIKDSTICSLARANDKDIQRAADALKPAESFRIHTFIATSPLHMEKKLRMTPDQVFEQARLAVRFARKFTDNVEFSPEDGSRSDMDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQIECTINGLGERAGNTSLEEIVMAVKTRKDYFGLDVGIDTSQIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSESELNAAFMRFKDLADRKAEIFDEDIIAIVSEESALAHEQEHFKFVSLSQHSETGEQPHAKVVFGVEGKEVTGEARGNGPVDATFNAIESEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKSGRIVNGVGTDPDIVAASAKAYISALNKLHSKDDKVNPQRS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: FUB12_GIBF5
Sequence: MPLPSRASSTPKISKACVPCRTRKIKCNAAVVGLPCGSCVSRECPDECVLSARKRRTVKGRNAEVPRSRKNIPDTNGSILSPRQQQLPTNVSRQTTDSSHSDPVEESIHASHTGSSLRNDTPHSRDRRPPGQAQADLLYLNILQDTVNDTSAAQTDASDHQSNDEPDDSFNSQIHHWNPPPQLDDVDNEYLAKKKVFELPPPRFMDDIVKAYFDYVHPFAPILNRIDFIQSYRSGSCCIFLLHAVAAAASLYVTHDVLIGCGYPDRSTAQASFFSKAKLFHDFHCQGDPLSMLQGSMILGAIILDHPSDRDFQYWFHNSVRRASKMGVQNACLRDDGSQKLYRRIWWVLHNRDIFHFFINTQNMRLLANAPPIRPLTEADWETEDIEQWSGILSPISQAQKVSLIAQCELAQIFGNVMSVVTSSNPSAEEIHKRILPLDAWRTSLPERMHLMASFAEGEIYHLEALTTSYRFECIMCRLLRRGRWQMSDGGLREWAQQRFRSAIFELDTIVKRVMINNMIQKLPTTFITTITALLALHIESALDAAESSLIRSMARISVQHTMLALDQIRDTPAIKRALPAFEIVLSKNKLYPMSTSDTEQINTMQTMSQDQALSDGHILQPPQTDMTLPQDDQSFLYGDFIGFDFLDRWQMEQLDFTGIY
What is the function of this protein?
Transcription factor that is involved in the formation of the two Fusaric acid derivatives, dehydrofusaric acid and fusarinolic acid, serving as a detoxification mechanism (PubMed:26662839).
What are the official names of this protein?
Fusaric acid cluster transcription factor FUB12, Fusaric acid biosynthesis protein 12.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2063_PSYIN
Sequence: MGRAYQNRKLSMAKTAGAKTKVYSKYGKEIYVAAKNGGFDPDGNLSLRHLIDGAKKDQVPTHVIERAIEKAKGGGGEDYERASYEGYGPGGCSVIVDCLTDNNKRTWTDVRNCFMKTGGNIGSPGTVAHMFEHQAVFVFKGEDDEAVLEELMMADVDVIDVEGEDGKITVFCPHTEFYKAKTALNEIYPNLELDIEEITFVPQIDHDIAPEHVDKFEKFMAMLEDCDDVQEVYHNAVLPDE
What are the official names of this protein?
Probable transcriptional regulatory protein Ping_2063.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXK2_HUMAN
Sequence: MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKGAALITAVACRIREAGQR
What is the function of this protein?
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880).  Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:29298880).  Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis (PubMed:18350175).
What are the official names of this protein?
Hexokinase-2, Hexokinase type II, HK II, Hexokinase-B, Muscle form hexokinase.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880). The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880). Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175).
Protein: LPXB_ECO27
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNGARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: GSTFA_ARATH
Sequence: MVLTIYAPLFASSKRAVVTLVEKGVSFETVNVDLMKGEQRQPEYLAIQPFGKIPVLVDGDYKIFESRAIMRYIAEKYRSQGPDLLGKTIEERGQVEQWLDVEATSYHPPLLALTLNIVFAPLMGFPADEKVIKESEEKLAEVLDVYEAQLSKNEYLAGDFVSLADLAHLPFTEYLVGPIGKAHLIKDRKHVSAWWDKISSRAAWKEVSAKYSLPV
What is the function of this protein?
In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC).  May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase F10, AtGSTF10, AtGSTF4, GST class-phi member 10, Protein EARLY RESPONSE TO DEHYDRATION 13.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GATC_DEHMC
Sequence: MKLNREDVLHIARLARLGLEEDEINRLSKELSALLEHFEVLQQVDTTGVEPTSQSTPVKSVLKEDIIKSSYAREDILSNAPRREGDYVRIRVVME
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CYSP_SALTY
Sequence: MAVNLLKKRPLTLAAMLLLAGQAQATELLNSSYDVSRELFAALNPPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKLIPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWSDLVRSDVKLIFPNPKTSGNARYTYLAAWGAADNADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFESEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQAQTIITHYYYRVNNPEIMGKQADKFPQTELFRVEEKFGSWPEVMKTHFASGGELDKLLAAGRK
What is the function of this protein?
Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  This protein specifically binds thiosulfate and is involved in its transmembrane transport (By similarity).
What are the official names of this protein?
Thiosulfate-binding protein.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic sulfate-binding protein family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PRM1_BOTFB
Sequence: MDAFKGYIASQKIQHSHAPSNDSSINSGHEMHPYGVNRNINAAPADDYYTPYLGLRARLSQTWINRWTVLLLLIIVRLLISLAGIKGDVASAKTEALSACSSVENVGSAMASMPHYLSQGVNSMAAAGITKAVNGMMQMLYMSLTGVEEIVLFVIHMMTSTYMCLITLAITGSLQVAIQMIEDVGAFMNKSIDTITGDMSSGLKSFEDDLNGFLSKINIGGIFGSSTSPPTIDLSSEINKLNSIQIDPTTMDADLAKLNASLPTFEQVQNFTDNIIKLPFEEVKKLVNESMIAYKFDDSVFPVPQKKSLTFCSDNTAIQDFFVGLVKTLDTAKKIILIVLVIAAILACIPMAFREIWGWRVMQIQAALLKSRSYTNEMDILYQAHRPYTSQFGLKLSRRFKGQKNQILARWFIAYATSIPALFVLALGLAGLFTCLCQFIVLKTLEKEIPALTAEVGDFAEHVVKALNNASESWALGANSVINNTNTEINDNVFGWVNTTTGAINETLNVFTDEMTKALNVTFGGTILYKPIMGVFECLVGLKIAGIEKGLTWVSDNAHVEFPEFQPDVFSLGAAASLSNTTADDNFLANPATSTTDEITNAVVKVGKKLEAVIRQEALISTALVAIYFVIVLIGLVHVIIGMCGRDKSRGEGGSAPTPLYRNTDVEAPNQHLPEISREKFGTSGNDGWHQEHMRAGGDPITRMPFGGGDGAADDLPYNGAPAPTYEASIAPTERLGVVPAGRVNTNRGPWVRDEKSRELWEADDMQRRATSSYGHLEGGDEKSSGWGVPPRRI
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGRC1_PIG
Sequence: MAAEDVAATGADPSELEGGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASDSDDDEPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLSDLTPAQQETLNDWDSQFTFKYHHVGKLLKEGEEPTVYSDEEEPKDESARKND
What is the function of this protein?
Component of a progesterone-binding protein complex.  Binds progesterone.  Has many reported cellular functions (heme homeostasis, interaction with CYPs).  Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan.  Intracellular heme chaperone.  Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins.
What are the official names of this protein?
Membrane-associated progesterone receptor component 1, mPR.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Smooth endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein; Extracellular side.
Protein: NIKR_OLEA2
Sequence: MGQTIRFGVSLDSDLLEKFDALCDERCYQTRSEAIRDLIRNTLVQQEWEDTGRDIAGTLTLVFDHHKSDLQQRLTEIQHDEHDLIITTLHVHLDHDNCLEVLVLKGPAERVRNLAQRLTSTRGVKHGKLSLTTTGQDLA
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: SYH_XYLFA
Sequence: MIKPRTPPGVLELLPREQIAFQRMLDVIRRNYERFGFLPVETPVFELSDVLLTKSGGETERQVYFVQSTGTLANAAESGATRLPELALRFDLTVPLARYVAEYEHVLAFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKQTLSIRYDAEVLAVIHAVFSELGIGDFQVQLNNRKVLRGFLESQGVRDGDLQLAVLREVDKLDKRGVLDVRDTLIGQGFGIPAAQVENILTFVATRSTSHADALVRLDALIEDSGPEAHEMLRQGVAELREVLTLVNVLGVPEHAYRLNFSIARGLDYYTGTVYETSLINHPQIGSICSGGRYENLANHYTQSKLPGVGISIGLTRLFWQLRDAGVMDGIAESSVQAMVVLMDEATLDDALDIARCLRIGGINTEVQMEAKKVSKQFQYASRAGIRFVVLAGDDERARGVVAVKDLTREQQFEIPREELASTLQVELEQAKVM
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRG2_CHICK
Sequence: MTPSNPTRLGSTALLNPAFSLKMMVWALVFLSLIQCSTQKGDDDYEDYTSNKTWVLTPKVHESDVTLILNGLLEGYDNKLRPDIGVKPTVIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDAHSCPLEFSSYGYPREEIIYQWKRSSVEVGDTRSWRLYQFSFTGLRNTTEVVKTTSGDYVVMSVYFNLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: Y2535_GEOTN
Sequence: MEKKFYLVREDILPEAMKKVVLAKQLLERKKAASVAEAAQLANISRGVFYKYRDAIFPFQAVTKENIVTLFFHLEDRSGTLSQLLSVVAAAGCNVLTIHQTIPLQGRANVTLSVSTNDMHEDIDELLAKLRGLEFVEKVEIVGSGVY
What are the official names of this protein?
UPF0735 ACT domain-containing protein GTNG_2535.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: NU1M_DROAL
Sequence: MEFILSLVGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BETI_PSEF5
Sequence: MPKVGMQPIRRQQLIEATLQAVDQVGMGDASIALIARLAGVSNGIISHYFRDKNGLIAATMGYIMSMLNEGVRARRQALTDDSPRAHLKVIIEGNFDASQVNGPAMKTWLAFWASSMHQPDLHRLQRINDHRLYSNLCCQFRRALPLYHARKAARGLAALIDGLWLRGALSGDAFDTDQAIRIAYEYMDLQLAKQER
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: URE2_RUEPO
Sequence: MIPGELFPAEGELILNQGRAVTRLMVANTGDRPVQVGSHYHFAETNPALEFDRGAARGMRLDIAAGTAVRFEPGQRREVVLIPIGGARRIYGFNQQVMGEL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_ARCFU
Sequence: MKVKEVIFAGRSNVGKSTLFSALFKFEVRKGKKPGTTIRPNSFQVGSVIFTDLPGFGYVSGYSRNFSERVKDFVVEYIETNARRIVASVEVIDASSFLEIAERWEKRGYIPVEIEMFEFLNDVTPRVFLAANKMDKVDDITNLNKIAEMLGMQPPWEKWRHVIYPVCAKKGEVSALKRDLKQYLLSLNLRDAAKAFR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: OTC_LISMF
Sequence: MTMYAKNNTAGKDMLSLLEWNKEELTDIIKLAVAMKTNPAHYSHILSGKILGMIFDKPSTRTRVSFEAGILQLGGQAIVMSSKELQIGRGEPIKDTAHVMSEYIDAIMIRTFSHEKVEELAYHAEIPIINGLTDLHHPCQALADLMTIYEWKDQLEGVKLAYIGDGNNVCHSLLLAGAMVGIDICLAMPKGYEVDETILAKAENLAKQSGGKIFVTEDPKLAVTDADFIYTDVWTSMGQEDENAKRLADFGEKYQVNAELVSGAKPDYHFLHCLPAHREEEVTAEIIDGNHSVIYQQAGNRLHAQKALLAAILEAK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_SOLM1
Sequence: MTESLAAVVLGIVEGATEFLPVSSTGHLILVGHLIGFTGEKADSFDVIIQLGAILAVVCLYWRRFWWLVSPKPHHAFSGIRGLWMLFLTSLPAGLIGLVARKSIKAYLFNPWSVALALSVGAVMIFLVEQRKTRDRYYSLDEMTPGLALGIGCFQCLSLWPGFSRSAATIMGGMLLGAKRSLAAEYSFIGAVPLMFAATLYDFYKSAHLFSADDLGVLGIGFVVSFVSALIAVKAFIVLVQRITLRPFAWYRLALAAAVFFFWPK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.