PharMolix/UniProtQA huggingface dataset:
Protein: NUSB_RHOOB
Sequence: MSGTHKKLGARHKARKRAVDFLFEAEARDLDPVDLATERAELSGKDDSVAPVAPYTVTVVTGVAENLDRLDEVISSHLQDWTLERLPAVDRAILRIAVWELFHATDVPPVVAVDEAVELAKQLSTDESPGFVNGILGQVVLVAPQVRSAAAATSRRAETADGESNDARS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RS2_LIMRJ
Sequence: MSVVSMKQLLEAGVHFGHQTRRWNPKMEEYIFTERNGIYIIDLQKTVKLIDTAYNYMKDVAANDGVALFVGTKKQAQDAIEEEATRAGQYYVNHRWLGGTLTNWKTIQSRIARLKELKKMSEDGTFDVLPKKEVAVLTKQREKLERFLGGIEDMPRIPDVMFIVDPHKEQIAVKEAQKLHIPIVAMVDTNTDPDDIDYVIPSNDDAIRAVRLITSKMADAFVEGKQGQDDAQQETADDNAANETVSEDSLKNLKNSVEGKED
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SYL_ALIFM
Sequence: MQEQYNPQDLEQKIQKHWDDNKTFVVTEDANKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVSRYQRLQGKNVMQPIGWDAFGLPAENAAVKNKTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCTPEYYRWEQEFFTKLYSKGLVYKKTSSVNWCPNDQTVLANEQVEDGCCWRCDTPVEQKKIPQWFIKITEYAQELLDDLDNLDGWPEMVKTMQRNWIGRSEGVELSFAVNGEESPLEVYTTRPDTLMGVTYVGIAAGHPLAEKASQNNPELAAFVEECRNTKVAEAELATMEKKGMDTGLRAIHPLNGREVPVFVANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVIKPEDGSDLDVSEAAYTEKGVLFDSGEFDGLAFQEAFDAIAAKLEAEGKGKKTVNFRLRDWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILPEDVVMDGVTSPIKADKEWAKTTFNGEPALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYSRFFHKLLRDAGYVTSDEPFKQLLCQGMVLADAFYYTNDKGGKEWVAPTDVTIERDAKGRIEKAVDDQGREVEHSGMIKMSKSKNNGIDPQEMVDKYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVHEHTNKGTTEALDTSSLTGDQKALRRDVHKTIAKVSDDIGRRQTFNTAIAAIMELMNKLNKAPQESAQDRALLDEALKAVVAMLYPMTPHASFAMWEALGESDLDSATWPTFDENALVEDEKTIVVMINGKLRAKLVVAADATEEHVRELGLKDENAMKFLDGLTIRKVIYVPGKLLNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP2_AJECN
Sequence: MGSKTPGNHRRGPNESSPHPAIDAINPPKQAAASRLVHSSLEGESEGGEDEDDDKPGADLKAVGQIGNNGQKRNKRRKKKKKNTKELEILQTTPPRVALANIFRSQRYPEAEIVKYSTDNDNLQRTTAEELRHISVLNAMDDEFLNDYRKAAEVHRQVRQYVQTIIKPGIALSQLAEEIEDGVRALTNHQGLETGDALKAGMAFPTGLCLNNIAAHWTPNPGAKEVILKYDDVLKIDFGVHVNGRIVDSAFTIAFNPVYDNLLAAVKDATNAGLKEAGIDARIAHISETIQNVMESYEVELNQKVIPVKAVRNITGHNVLHYKIHGDKQVPFVKTQTNQRMEEGDVFAIETFGSTGKAYLDDATGIYGYGYDENASTAGLHHSSAKSLLKTIKENFGTLVFSRRYLERLGVQRYHLGMRSLVTNGIVQSYAPLVDVPGSYVAQFEHTVLLRPNCKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_STRPS
Sequence: MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARINLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQEIKGTGMTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PA2H_GLOUS
Sequence: SLLQFRKMIKKMTGKEPVVSYAFYGCYCGSGGRGKPKDATDRCCFVHQCCYEKVTGCDPKWDDYTYSWKDGDIVCGGDDPCKKEVCECDRAAAICFRDNLKTYKKIYMAYPDIFCSSKSEKC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) homolog that shows local myotoxicity, apparent anticoagulant activity (PubMed:15618013), and neurotoxicity (PubMed:17299814).  Shows analgesic effect on mice due to a decrease of action potentials and nerve conduction velocity.  These effects are caused by inhibition of voltage-gated ion channels (potassium (Kv) and sodium (Nav)) (PubMed:19277489).  In addition, analgesic effects are antagonized by naloxone, implying the mechanism of action is correlated with opioid receptors (probably indirectly) (PubMed:17299814).  Does not show detectable PLA2 activity on egg yolk phospholipids (PubMed:15618013).
What are the official names of this protein?
Basic phospholipase A2 homolog Gln49-PLA2, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. Q49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_YERPN
Sequence: MDKKAARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEILVAASTVEKAINEQLKYAGNKDAAAAVGKTIAERALEKGITKVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IH5GT_IRIHO
Sequence: MAKQHFLVITIGAQGHINPARRLAARLIEAGGARVTLTVPILAYRRMFPSAAAELEPREEKDDGLLTYMPYSDGVEDGLDPAANPAEFKRRIAESLRCIAAGFVARGRPITCIVYALLLSMAAAVARDLGVPSVLFWIQSATSFAVNYHYFAGGYDKLFSEAAADPSFLVELPGLPAFRRKDLPTLLTGPRPEGTFYSFLHTLYGEVFETLRREVSAGEEKPRVILNTFRALEEDVVAGFEASIDMVTVGPLVPPSLIMTSPEETATNDLYEHDTSNYMEWLDGKEEGSVVYVSFGSYATLKEEEREEVKKGLSASGRPYIWAMAKGGSGDDGGGLGVKVEWCEQARVLSHRSVGCFVTHCGWNSVAEAMACGVPMVMLPQWTDQVTNAKLAEEEWGVGVRAEAVAGEELRRCLDVVMGGGEADDGGIVMRRRAKAWSEKAREAAGDGGSSARNLAAFVVGGN
What is the function of this protein?
Catalyzes the transfer of the glucosyl moiety from UDP-glucose to the 5-hydroxyl group of anthocyanin.  Anthocyanins are ubiquitous colored pigments that are responsible for variations in petal color.  Also acts on the 3-O-rutinosides of pelargonidin, delphinidin and malvidin, but not the corresponding glucosides or 6-acylglucosides.  Does not catalyze the glucosylation of the 5-hydroxy group of cyanidin 3-glucoside.
What are the official names of this protein?
Cyanidin 3-O-rutinoside 5-O-glucosyltransferase, Ih5GT, Anthocyanin 5-O-glucosyltransferase, Cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase, Uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PUR5_SHEPA
Sequence: MSTPTTPLSYKDAGVDIDAGNALVNNIKSAVKRTRRPEVMGNLGGFGALCELPTKYKHPVLVSGTDGVGTKLRLAIDYKKHDNVGVDLVAMCSNDLIVSGAEPLFFLDYYATGKLDVEVATAVVKGIAEGCVQSGCALIGGETAEMPGMYEGDDYDLAGFCVGVVEKEEIIDGTKVQDGDALIALASSGPHSNGFSLIRKVLEVSKADPAQELAGKPLIDHLLEPTKIYVKSLLKLLEQHDVHAMSHITGGGFWENIPRVLPEDCKAVVKSDSWQWPVVFNWLMENGNISEFEMYRTFNCGVGMVVALPADKVDSALELLTAEGENAWLIGNIAKRNGEEEQVEIL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_XANC5
Sequence: MELVITGSNNKVSVSDAVFGREFSEDLVHQVVVAYRNAGRAGTKAQKTRSEVAGTTKKSKKQKGGGARHGALTAPIFVGGGVTFAAKPRSFEQKVNRKMYRAAICAIFSELNRQGRLMIVDAFDLEATKTKGLIEKLKGLEVGKRPLIVTEEASEHLYLSARNLPYVQVRDVQGLDPVALVGADTVVITADAVKKVEEWLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KAPCG_MACMU
Sequence: MGNAAAKKDTEQETVNEFLAKARGDFLYRWGNPAQNTASSDQFERLKTLGTGSYGRVMLVRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINFPFLVKLQFSFKDNSNLYLVMEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEI
What is the function of this protein?
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit gamma, PKA C-gamma.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: RP54_RHIET
Sequence: MALSANLFLRQSQSLVMTPQLMQSIQLLQMTHFELNQFIAQEVEKNPLLEFPSNDGEAGDERGAGEDEPFGQPSEDAGSDDGADSRAEALSSDWYDNGGSESTGRLNDELDANYTNVFPDDGGPQRLDAPELVGQWKSMPGSAEGADYDLDDFVAGQLSLRDHLAQQIPFVLPDMTDRLIAQNFVDQLDDAGYLQTDLVETGERLGTSLEQVEHVLAALQTLDPPGVFARSLAECLAIQLRQKDRYDPAMQALVANLELLARRDFATLKRLCGVDEEDLLDMLGEIRQLNPKPGGGFEAGVSEAIMPDVVVRPSADGGWLVELNPDTLPRVLVNQSYFSRVTRNGEDHAFLSECLQSANWLTRTLDQRAKTIMKVASEIVRQQDAFLLNGVDHLRPLNLKTVAEAIKMHESTVSRVTSNKYMLTPRGLFELKYFFTVSISAVEGGEQHSAEAVRATRFRALIMQESPDAVLSDDDIVDMLKKGGIDLARRTVAKYREAMNIASSVQRRREKRALAKVAGF
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of the nitrogen fixation genes (nif operon), GlnA and DctA for dicarboxylate transport.  The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator proteins NifA, NtrC, or DctD for the expression of the regulated proteins (By similarity).
What are the official names of this protein?
RNA polymerase sigma-54 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: CR3L3_BOVIN
Sequence: MDGDLAIGKMASSTSPMGPIDSLELLDLLFDRQDGVLRHVELGEDWGHGEDQVLPGADSDDFLNSILGSGDSDSPTWSPAASDSGISEDLPSDTQDTPPHGGVPATPAGCHSVESGKGPCPSYHPGPTCPARHLGPVAPRLETSVAIDLEMWSPGVYAEEQTDLADSPSRYNLTVKDLLLSSSSGDLQQHHLAAPHLLRPGTGHCQELVLTEDEKKLLAKEGITLPTQLPLTKYEERMLKKIRRKIRNKQSAQESRKKKKEYIDGLETRMSACTAQNQELQRKVLHLEKQNLSLLEQLKKLQAIVVQSTSKSAQTGTCIAVLLFSFALIVLPSISPFASNRAESPGDFAPVRVFSRTLHNDAASRVAPDTAPGSEAPGPGPNTGALQERSPGSPPGEWESQDTRALDNSTEDLDNSTLVQGNSVKELDQATLLDCAPPEPAVSPGHVGLEAAGGEL
What is the function of this protein?
Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes.  Activated in response to cAMP stimulation.  In vitro, binds the cAMP response element (CRE).  Activates transcription through box-B element and CRE.  Seems to function synergistically with ATF6.  In acute inflammatory response, may activate expression of acute phase response (APR) genes.  May be involved in growth suppression (By similarity).  Regulates FGF21 transcription (By similarity).  Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (By similarity).
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 3-like protein 3, cAMP-responsive element-binding protein 3-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus.
Protein: ERA_SALG2
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: BFD_ECOL6
Sequence: MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVRAAREVMEDELMQLPEFKESA
What is the function of this protein?
Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR.  Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes) (By similarity).
What are the official names of this protein?
Bacterioferritin-associated ferredoxin.
Protein: NUP42_DANRE
Sequence: MPVCNFFLQGRCRYGDTCWNEHPTGGRGGDYRGNQQPSNRGGFGNRVWINPSQRGGGGSSSAGGSNEWGRGAASARDVQSSEFSFSQNRFSALETQRAGAEDTHTTLDTIQKEMEVWQTSGQWPFSCYSAVNRQISGFIELCPEELRLEYYTSRASGDIQPYINSVQQLANQWRSRVQELRNMSSSTQISVIAELKSSSPPASAPGFGSPGPGFGSATSGFGNTSLSSPPAGFGGAGFGSGPQSSSTFSFAQSKTDFGASNTQQASGFGSSAFAQPSSGFGNPAPSAASFSFAAADSESKPSAGGFGSASGFSFKTATAGQGSGFGSGFGSSSGFGSSSGFGSSSGFGSAFGSAAPAQSSSFGSTGGAADTQSGHGLFTANSELTPEELKEFMAKRFTLGQIPLRPPPADLLMI
What is the function of this protein?
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
What are the official names of this protein?
Nucleoporin NUP42, Nucleoporin-like protein 2.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CBPM_SALDC
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: YLAC_STAXY
Sequence: LTEVVKAQSFTKAAENLYTSQPSISRDIKRLENDYDVKVFEFKHSKMTLTSDGEKLYQYVLQRNYLEQALRQDLKMQNNAVAGDLKLGSSFTFGEYRLSRQLTKLAQMYPELHIHVHLDNSETIVEQIKNNIVDVGIVEKKIQNNAIISTPIAQDEIVLIKKKSSSSNLETCFIREQGSGTRVYQENGLNQLSLNPYLVVINNTSLIKSMVHAGNGFSIVSKSTLTSEDLEQLEVINLDIERFFYLILHKDKYIDEKMKRVISVLKQNVE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator in lacR 5'region.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GREA_HELPH
Sequence: MNKEPMSMHGYNKICAELKQLKEVERPNIVKEIDIARGHGDLKENAEYHAAKEKQRFIEARIVDLSEIVANAQVIDPSVLAHNKVSFGSTIKILNLDNDKEFSYTIVGSVESDPAKGLISFGSPIAKSLIGKSKGDAVSIQLPNGESDFEILDIYYKEICFDEN
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: VP35_MABVA
Sequence: MWDSSYMQQVSEGLMTGKVPIDQVFGTNPLEKLYKRRKPKGTVGLQCSPCLMSKATSTDDIIWDQLVVRKTLADLLIPINRQISDIQSTLSEVTTRVHEIERQLHEITPVLKMGRTLEAISKGMSEMLAKYDHLVISTGRTTAPAAAFDAYLNEHGVPPPQPAIFKDLGVAQQACSKGTTVKNATTDAADKMSKVLELSEETFSKPNLSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILSEGENAQAALTRLSRTFDAFLGVVPPVIRVKNFQTVPRPCQKSLRAVPPNPTIDKGWVCVYSSEQGETRALKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
What are the official names of this protein?
Polymerase cofactor VP35, Marburg VP35, mVP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: FAT2_CAEEL
Sequence: MTIATKVNTNKKDLDTIKVPELPSVAAVKAAIPEHCFVKDPLTSISYLIKDYVLLAGLYFAVPYIEHYLGWIGLLGWYWAMGIVGSALFCVGHDCGHGSFSDYEWLNDLCGHLAHAPILAPFWPWQKSHRQHHQYTSHVEKDKGHPWVTEEDYNNRTAIEKYFAVIPISGWLRWNPIYTIVGLPDGSHFWPWSRLFETTEDRVKCAVSGVACAICAYIAFVLCDYSVYTFVKYYYIPLLFQGLILVIITYLQHQNEDIEVYEADEWGFVRGQTQTIDRHWGFGLDNIMHNITNGHVAHHFFFTKIPHYHLLEATPAIKKALEPLKDTQYGYKREVNYNWFFKYLHYNVTLDYLTHKAKGVLQYRSGVEAAKAKKAQ
What is the function of this protein?
Can function as a Delta(12)/Delta(15) bifunctional desaturase and behaves as a nu +3' desaturase.  Introduces a double bond in the fatty acid chain three carbons away from an existing double bond to biosynthesize polyunsaturated fatty acids (PUFAs) endogenously (PUFAs are essential for membrane structure and many cellular and physiological processes).  Acts on a number of substrates like oleoyl-CoA ((9Z)-octadecenoyl-CoA, 18:1n-9), palmitoleoyl-CoA ((9Z)-hexadecenoyl-CoA, 16:1n-7), and gamma-linolenoyl-CoA ((6Z,9Z,12Z)-octadecatrienoyl-CoA, 18:3n-6), to generate linoleoyl-CoA ((9Z,12Z)-octadecadienoyl-CoA, 18:2n-6), (9Z,12Z)-hexadecadienoyl-CoA (16:2n-4) and (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA (18:4n-3) respectively (PubMed:10775428, PubMed:11972048, PubMed:22041902, PubMed:26806391).  Unlike plants, Caenorhabditis elegans desaturases seem to use fatty acyl-CoAs as substrates (Probable).
What are the official names of this protein?
Delta(12) fatty acid desaturase fat-2, FAT-2, Fatty acid desaturase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BAP3_YEAST
Sequence: MSDPIVTSSKMEKSAEFEVTDSALYNNFNTSTTASLTPEIKEHSEESRNGLVHRFVDSFRRAESQRLEEDNDLEDGTKSMKSNNHLKKSMKSRHVVMMSLGTGIGTGLLVANAKGLSLAGPGSLVIGYVMVSFVTYFMVQAAGEMGVTYPTLPGNFNAYNSIFISKSFGFATTWLFCIQWLTVLPLELITSSMTVKYWNDTINADVFIVIFYVFLLFIHFFGVKAYGETEFIFNSCKILMVAGFIILSVVINCGGAGVDGYIGGKYWRDPGSFAEGSGATRFKGICYILVSAYFSFGGIELFVLSINEQSNPRKSTPVAAKRSVYRILIIYLLTMILIGFNVPHNNDQLMGSGGSATHASPYVLAASIHKVRVIPHIINAVILISVISVANSALYAAPRLMCSLAQQGYAPKFLNYIDREGRPLRALVVCSLVGVVGFVACSPQEEQAFTWLAAIAGLSELFTWSGIMLSHIRFRKAMKVQGRSLDEVGYKANTGIWGSYYGVFFNMLVFMAQFWVALSPIGNGGKCDAQAFFESYLAAPLWIFMYVGYMVYKRDFTFLNPLDKIDLDFHRRVYDPEIMRQEDEENKERLKNSSIFVRVYKFWC
What is the function of this protein?
Involved in transport of isoleucine, leucine, valine, cysteine, methionine, phenylalanine, tyrosine and tryptophan.
What are the official names of this protein?
Valine amino-acid permease, Branched-chain amino-acid permease 3.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YIDD_XYLFT
Sequence: MHKVIMHPLILLLKIYKRLISPLLGPHCRFEPSCSEYAMVAIARFGTLRGIWLAARRLARCHPLQLGGHDPVPDNTSTQVNPRSHRCTGHHQ
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS14_STAA2
Sequence: MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSSPTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: VATB_METTL
Sequence: NTNETKVRFTGETAKIGVSLEMLGRIFNGAGKPIDGGPEIIPEKKLDINGYPLNPVSRNPPNAFVQTGISTIDGTNTLVRGQKLPIFSGSGLPHNTLAAQIARQAKVRGEGEQFAVVFAAMGITNEEANYFMEEFKKPGALENAVVFINLANDPAIERIITPRLALTTAEYLAYEKDMHVLVVLTDMTNYCEALREIAAARNEVPGRRGYPGYMYTDLATLYERAGRVKGRKGTVTQIPILTMPHDDITHPIP
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: UPPP_BIFLO
Sequence: MNFFQAIILGIVQALTEYLPVSSSAHIRIFGDLMLGSDPGAAFTAIIQIGTELAVILYFRHDIINILTHWFSCLFGKNGKDWKARMGRGDNYATLGWNIIVGSIPIIILGFTLQNVIETSLRNLWITVTVLLVFGILLWMVDAKARQNKTMNDMTYRDAFLFGLGQSMALIPGVSRSGGTITVGRALGYTREAAVRLSFLMAIPAVFGSGLLEAIKAVKNYKTDAMFPGWGPTLVAMVISFVLGYIVIIGFLKFVSNFSYKAFAIYRIGLAVVVALLLIVGVLPAIDPSVVAAA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2618_STAA3
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGRFSRKSMVYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein SAUSA300_2618.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MPC3_YEAST
Sequence: MSASAFNFAFRRFWNSETGPKTVHFWAPTLKWGLVFAGLNDIKRPVEKVSGAQNLSLLATALIWTRWSFVIKPKNYLLASVNFFLGCTAGYHLTRIANFRIRNGDSFKQVIHYIIKGETPAAVAAKQTASTSMNKGVIGTNPPITH
What is the function of this protein?
Mediates the uptake of pyruvate into mitochondria.
What are the official names of this protein?
Mitochondrial pyruvate carrier 3, MPC3, Protein FMP43.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.