PharMolix/UniProtQA huggingface dataset:
Protein: Y5319_PSEAE
Sequence: MSIRDWPEAERPREKLLEQGAAALSDAELLAIFLRTGVTGCSAVELSRRLLSEFGGLRALLEADLASFCGHLGLGVAKYAQLQAVLEMGRRHLAERLRRDSILESPQAVRDYLKARLRHEQHEVFACLFLDTRHRVLSFEVLFQGSIDGASVYPRQVVKRTLAHNAAALILTHNHPSGDARPSLADRQLTARLKEALALIDVRVLDHFIIGDGEPLSLAEYGWL
What are the official names of this protein?
UPF0758 protein PA5319.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: EFG_PLARO
Sequence: LQDGAYHEVDSSEMAFKIAGSMAFKEAARKAYAVILEPLMAVEVTTPEDYMGDVIGDLKGPRRQIRAMDERAGARVVQALVTLLDIFGYVGDLRSKTQGRASFSMQFDSYAEVPQHIAKKIVAKVRAQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BUCBP
Sequence: MSVNIVVIGMQWGDEGKGKIVDFLATHADYVVRYQGGHNAGHTLVVDNKKIVLHVLPSGILHNNIISIIANGVVLEPQSFINEIKLLEAENLCIRKRIFISESCNLIFPYHVFMDLAREKQKYRNFIGTTGCGIGPAYEDKVARRGLCVGDLLDLSFFSRKLEENVNFYNHQFTNFYHTEKVSFKEIFSNLLKVSDVIISMINDIPDLLNNAINDNKSIIFEGAQGTLLDIDHGIYPYVTSSSSVSGSVCSGAGVGIKNLGDIYGVVKAYSTRVGNGPFPTELFGELDAYFCRFGNEFGATTGRRRRTGWLDIVLLRRVISINSITKICLTKLDILDNLEKILICTSYHLKGVKNKKWDSVPFCRNDWDKIKPVYETFLGWKQNTRGITEFDELPKLAKKYIHRIEELIKVPVYIISTGPDRQDIIIRN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR8_SCHPO
Sequence: MGGAAGGKTYLGWWGHLGGPKQKGIITYSLSPFQQRPMAGFFKTSTQNMFRRVMTEGLYVAIPFGIAYYIYCWGKERNEFLNSKHGRHLVEE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 8, Complex III subunit 8, Ubiquinol-cytochrome c reductase complex 11 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
What is the protein family that this protein belongs to?
Belongs to the UQCRQ/QCR8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS14Z_CLONN
Sequence: MARKAMIEKWKKTPKYSTRAYTRCRICGRPHSVLKKYGICRICFRELAYRGQIPGCKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NCAP_I82A7
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSVGKDPKKTGGPIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMNMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQKAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSGFIRGKKVIPRGKLSTRGVQIASNENVETMDSSTLELRSRYWAIRTRSGGNTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFIGNNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PLGT3_MOUSE
Sequence: MQALPLGLQLALLVAAGAGARVSAPRSLAWGPGLQAAAVLPVRYFFLQSVDSDGRNFTSSPPGQTQFKVVVKSLSPKELVRIYVPKPLDRNDGTFLVRYRMHETAHKGLKIEILHGSEHVAHSPYILKGPVYHEYCDCPEDDPQVWQETLSCPASEPQIEQDFVSFPSINLQQMLKEVPTRFGDERGAVVHYTILNNHIYRRSLGKYTDFKMFSDEILLSLARKVTLPDLEFYINLGDWPLEHRKVNDTPGPIPIISWCGSLDSRDIILPTYDVTHSTLEAMRGVTNDLLSVQGNTGPSWINKTEKAFFRGRDSREERLQLVLLSKENPQLLDAGITGYFFFQEKEKELGKAKLMGFFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQESPYYEHFYVALKPWKHYVPIKRNLGDLLEKVKWAKENDEEAKKIAKEGQLTARDLLQPPRLYCYYYRVLQKYAERQASKPMIRDGMELVPQPDDGTSICQCHRRRPEREEL
What is the function of this protein?
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C.  Can also catalyze the transfer of xylose from UDP-xylose but less efficiently.  Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1.  May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
What are the official names of this protein?
Protein O-glucosyltransferase 3, KDEL motif-containing protein 2, Protein O-xylosyltransferase POGLUT3.
What is the protein family that this protein belongs to?
Belongs to the KDELC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CBIT_ARCFU
Sequence: MTGKFTKEEVIGVVFSKLRPSPNDVFADIGCGSGAVTEFFAPYVRKAYAIDIEISDEARERLKRFDNVVLLEMDGKEFLKKYSPDVVFIGGTKGVEEMLEICNARRVVVNAARIEVALSAARKMREKGIFREIVLVNAAKSYELAGGLAFRSLNPVFVVFGER
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: CCNK_HUMAN
Sequence: MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAAWMR
What is the function of this protein?
Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases.  Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).
What are the official names of this protein?
Cyclin-K.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
Protein: TOP2M_DICDI
Sequence: MSKLLNNNNHKNLTNYLKFGKGIINNLNNKSKQVGIISFISQSSIQSQSSIQSQSFLSINNNSNNKYFSTKLNKNEKISEKTTTRKIEDIYQKKTPTEHVLLRPDSYIGTIEKIEDDMWVLSNSMFNKEKKTIELNNDNNEKNVESTTTTTTKTNKKPLTYIHPIKATYIPGLLKIYDEILVNAADNKKRDSKMSFIKVEINPNENSISIMNDGKGIPVVMHQTENCYVVEMVMGNLMSGSNFNDSELKVVGGRNGFGAKLTNIFSKEFTVETVDKSSGKKYFQRWSNNMGDRSEPIITPIGEGESDYTKITFKPDLEKFKIKSLWDDNILQLMERRLYDIAGCNTELMVTLNGKRLNYNFQSYVKLYEHHLNNSTKREDNEEQYREESFEFGEISPRWKIGIGLSETGQFTQVSFVNSINTVKGGTHVNFLADQIVRYVGEKLKKKHSDLEIRPMNIKHHLALFVNCLVDNPSFDSQSKETLTTKPMLFGSTPEIPESLLAQFVKNSKIIERVAGWALMKQKADLIHSTSGRQSKTTLIKSISKLDDANWAGGLKSKECTLIITEGDSAKSLALAGLSVVGRNSYGVFPLRGKLLNVRDVASKQLLSNEEINNLTTILGLSHKNSYDTDESMEDLRYGRVMIMADQDHDGSHIKGLVMNFIHYFWPNLLKRGFLVEFVTPIIKATKSSTQKKSFFTIKDYEKWRETISSDQLKQYTIKYYKGLGTSTSAEAKEYFSNLDKHVIKFIWGDEADDLIKMAFAKDLSSLRQRWIKETDMSQGIDHSIKEITYPDFINKELIHYSWAANLRSIPSLIDGLKPGQRKILFASFKRRLTNEIKVSQLSGYVAEQTSYHHGEQSLNSTIVKMAHNFVGSNNLPLLTPSGQFGTRLQGGSDSASARYIFTKLEPVARYLFNELDDPLLNYLEEEGESIQPDYYIPIIPMLLVNGSEGIGVGMSTSIPLFSPIDIIDQLMLRLNNQVALKKLIPWYRGFKGTISPDRHTYRTNGVIKLVGRNLEITELPIGRWTSDYKEVLNDLIDKDVIKSFQESNTENSVHFTILLNNNQLEQMEDLTENELIKLFKLSASLNFHLTCFDENSKIQKLESVEEIIDQFYKVRLQFYGKRREYLLKSLDNQIKRLTTTIQFLEVIASGKLKIQGRSKQDLIKELESGEIVGFENFGTHPPEVYQHLFSLSILDITKERIDNLTNQLTKRKSEHQSISSSDPKSLWTADLQQLKEYLEKSDKEFQKKPLKTSSSSSFDVSSSSESAKLSSTRKSKTDKIKSK
What is the function of this protein?
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.  Topoisomerase II makes double-strand breaks (By similarity).
What are the official names of this protein?
DNA topoisomerase 2, mitochondrial, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APAG_ECO24
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: NEP2_SCHPO
Sequence: MRSNSIFTKEIDSEAVKKSSNLRPPSTGSSNSNGSDTASPKKKKKGFFRSLFGSSSSGSKSCGSPFTRIWLEYFEVSLRKNDVDHFRPGYWILDTNIDFFYEIMLRQVLLKRPKEESQQIYLLRPAMVFFLAQAPNPLEIESALPPAMFDASFIFLPINDTNECGIESGSHWSLLVVSVEKGLGWYYDSMSNGNTNDCNLAIKNLGILLKKEFRVRHMKTPQQINDCDCGLHVCENTRILMYRLLQKPYVPKVDMNLDHSVVDSVRLRKALMEVITSLLAAYGSKVPKPSETHTDPEKDKKIFSKICKTEELLELPTLSAVTSDSAQPHSLPASMPSSQPQSRSESLPLTHPNSEPNPKLDSQPNSSPVRRPSLIKVKTASTSVLPTSILQRPPSIVPRPETAAIQHTQQSIEIH
What is the function of this protein?
Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity).  Has a role in meiosis.
What are the official names of this protein?
NEDD8-specific protease 2, Meiotically up-regulated gene 120 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCH1_MYCTU
Sequence: MSQLDSRSASARIRVFDQQRAEAAVRELLYAIGEDPDRDGLVATPSRVARSYREMFAGLYTDPDSVLNTMFDEDHDELVLVKEIPMYSTCEHHLVAFHGVAHVGYIPGDDGRVTGLSKIARLVDLYAKRPQVQERLTSQIADALMKKLDPRGVIVVIEAEHLCMAMRGVRKPGSVTTTSAVRGLFKTNAASRAEALDLILRK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DNLJ_LEGPH
Sequence: MNDQGIKESIETLKEQIRKYDYHYYVLDEPLVPDAEYDRCFKALQQYEEQYPQFLSPDSPTQRVSGTPSDAFMPVAHKQPMLSLSNVFTTDELKAFIKRAIEKLDEPNQQLVFACEPKLDGLAVNMTYEGGILTHAATRGDGAVGENITANIKTIASVPLRLRVSNPPKLIEVRGEVYIPKADFEAYNARARELGEKTFANPRNAAAGSLRQLNPEISASRPLAIYCYGIGACEDYKLPNSHLEQLNLLKEFGFRVSPETRRAVGVEGCLDYYQYMLAKRNQLPFEIDGVVYKIDSISLQQQLGYVSRAPRFACAHKFPATEEMTRLIAVDFQVGRTGAVTPVARLEPVSVGGVTVSNATLHNFDEITRKDIRIGDTVIIRRAGDVIPEVVSVILEKRPANARMIELPKNCPVCGSEVVREADEAIARCVGGLYCKAQLKRMMWHFASRKAMYIEGLGSVLIDQLVDEGIVHHLADLYELDLQTLANLPRMGEKSAKNLLSALEKSKKTTFNRFLYALGIREIGEAGARVLAEHYCDVESLKAATIEELMTLNDIGPVAASHIVHFFAQAHNLEVIDRLLELGIHWPKPEKIQVNQQNPFFGKTVVLTGTLSTMGREEAKAKLLALGAKVSGSVSSKTDYVVAGSEAGSKLIKATELGVAIIEEDEFLKWVNS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PLYE_NEOFI
Sequence: MYQPLLLLPLLLTSAFATPHDPTTHQALDKRASFPIPSSKGSVTYSSPKSVSGTFDGGLKTYGRGVKCSGQKEGGDKDAVFILEDGATLKNAIIGADQIEGVHCKGSCTIQNVWWTDVCEDALSLKGSGSGTHRIIGGGARNADDKVIQHNSGGKVTIQDFTVQNFGKLYRACGNCSKQFKRTVEISGVKASSGKSLVGINSNYGDTATISGCASSVKEICVEYEGTDNNDKEPKKKGSGPSNACKYKEPLSKC
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase E.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CBG_PIG
Sequence: MLLTLYACLLWLSTSGLWTSQAKDPDSDLSTRSRHRNLAPNNVDFAFALYKHLVASAPGKDVFLSPVSISTALAMLSLGASGYTREQLLQGLGFNLTETPEAEIHQDFQHLHSLLKGSNITSEMTMGNALFLDRSLELLESFSTGSKHYYGLEALAADFQDWAGASRQINEYIKNKTQGKIVDLFLEQDSSAMLILINYIFFKGTWTHSFPPESTREENFYVNETATVKVPMMFQSRAMKYLNDSLLPCQLVQLEYTGNETAFFILPVKGEMDTVIAGLSRDTIQRWSKSLIPSQVDLYVPKVSISGAYDLGSILGDMGIVDLLSHPTHFSGITQNALPKMSKVVHKAVLQFDEKGMEAAAPTTRGRSLHAAPKPVTVHFNRPFIVMVFDHFTWSSLFLGKIVNLT
What is the function of this protein?
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
What are the official names of this protein?
Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRCB_BURO0
Sequence: MFYSIVAIFVGAGLGALLRWFLSLALNAFFPAVPLGTLASNLIGGYVIGVAAVVFTVRVGLPPEWRLFVITGFLGGLTTFSTYSVEVMTHALEGEFGWALAVAALHLTGSFALTALGMWTARAWLAVA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
Protein: PYRG_STRA5
Sequence: MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLKKERRGEYLGATVQVIPHVTDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGSDNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEQPAGQSIKNKLAQFCDVAPEAVIESLDVDHIYQIPLNMQAQNMDQIVCDHLKLETPAADMTEWSAMVDKVMNLEKKVKIALVGKYVELPDAYLSVVEALKHSGYVNDVAIDLKWVNAAEVTEDNIKELVGDADGIIVPGGFGQRGSEGKIEAIRYARENDVPMLGVCLGMQLTCVEFARNVLNLHGANSAELDPKTPFPIIDIMRDQIDIEDMGGTLRLGLYPCKLKSGSRAAAAYNNQEVVQRRHRHRYEFNTKFREQFEAAGFVFSGVSPDNRLMEVVELPEKKFFVAAQYHPELQSRPNHAEELYTAFVTAAVENMK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ISPH_NEIM0
Sequence: MNGKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIEDLAEVPPGATLIYSAHGVSKAVQQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAAGIGTDAYMVDNASYLQRAWFEGKNKVGVTAGASAPEVLVQEVLATIRRWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: YEDL_ECOLI
Sequence: MFTIKTDDLTHPAVQALVAYHISGMLQQSPPESSHALDVQKLRNPTVTFWSVWEGEQLAGIGALKLLDDKHGELKSMRTAPNYLRRGVASLILRHILQVAQDRCLHRLSLETGTQAGFTACHQLYLKHGFADCEPFADYRLDPHSRFLSLTLCENNELP
What are the official names of this protein?
Uncharacterized N-acetyltransferase YedL.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: PNP_HAEI8
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKDVKEGQDFFPLTVNYQERTYAAGKIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFFNEIQVVATVVSVNPQISPDLVAMIGASAALTLSGVPFNGPIGAARVGFIDNQFVLNPTMAEQKQSRLDLVVAGTDKAVLMVESEADILTEEQMLAAVVFGHQQQQVVIEAVKEFAKEAGKPRWDWVAPQPNTDLINKVKAIAEARLGDAYRITEKQARYEQIDAIKADVIAQITAEDEEISESKIVDIFTALESQIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGERQDHFLFHYNFPPYSVGETGMIGSPKRREIGHGRLAKRGVAAVMPSLAEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKSARMHILGVMEQAIPAPRADISDYAPRIYTMKIDPKKIKDVIGKGGATIRSLTEETGTSIDIDDDGTVKIAAVDSNAAKNVMGRIEEIVAEVEAGAIYKGKVTRLADFGAFVAIVGNKEGLVHISQIAEERVEKVSDYLQVGQEVNVKVVEIDRQGRIRLTMKDLAPKQETEINQEDPVEEQE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_THESQ
Sequence: MKQEKLSLNDVLIRPIITEKALILREQRKYVFEVNPLANKNLVKEAVEKLFNVKVEKVNILNMKPKPKRRGIFEGKTRSWKKAVVTLKEGYTIKELEGEH
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HMD_METVS
Sequence: MKVAILGAGCYRTHAASGITNFSRAAQVAKEVGIPEITMTHSTITMGAELLHLIPEVTEVVVSDPCFAEEPGIVVLDQFDYGAVMEAHLAGDAEKVMPEIRAAVKAKAKETPKPPKGCIHFVHPEKVGLKVTSNDVEAVKDADIVITWLPKGGSQPAIIEKFASEIKKGAVVTHACTIPTPKFAKIFKDLGRDDLNIISFHPGAVPEMKGQAFLSEGLADAEKVEEFYCIAKAARGEAFKMPANLISPVCDMGSAVTAPVYAAILAYRDAVTQILGAPADFAQMMADEAISQMLDLMRKEGIKNMEEKLSPKALTGTADSMCFGPLAEILPASLKVLEKHAKENKCECGCSIKP
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
5,10-methenyltetrahydromethanopterin hydrogenase, H(2)-dependent methylene-H(4)MPT dehydrogenase, H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase, N(5),N(10)-methenyltetrahydromethanopterin hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the HMD family.
Protein: CASTO_LOTJA
Sequence: MSLDSEVSVSSSSGRDWFFPSPSFFRSSPSQYGRRFHTNSNTHSAPSSTYPSGIRHRRRVKFSRTPTTSSNEKPQISIVSDKPSAISKNNLNWLSQFGLQFALVTLTIVFLLLLLLRNTHLESQVNKLQGEILRLHACHQLDTLNVSSSTAHKSQDTHPCSCENFKRNLALFLSFMLLLIPLIIFKYIDYVSRSRLSENISEQVSLNKQIAYRVDVFLSVYPYAKPLVLLVATLLLIFLGGLTLFGVTTEDLGHCLWLSWTYVADSGNHASSEGIGPRLVAVSISFGGMLIFAMMLGLVSDAISEKFDSLRKGKSEVVEQNHTLILGWSDKLGSLLNQLAIANESLGGGTIAVMAERDKEDMELDIGKMEFDFKGTSVICRSGSPLILADLKKVSVSKARTIIVLAEDGNADQSDARALRTVLSLTGVKEGLRGHIVVEMSDLDNEVLVKLVGGDLVETVVAHDVIGRLMIQCARQPGLAQIWEDILGFENCEFYIKRWPQLDGMLFEDVLISFPAAIPCGIKVASYGGKIILNPDDSYVLQEGDEVLVIAEDDDTYAPAPLPMVRRGSLPKDFVYPKSPERILFCGWRRDMEDMITVLDASLAPDSELWMFNDVPEKEREKKLIDGGLDISRLENISLVNREGNAVIRRHLESLPLESFDSILILADESVEDSAIQADSRSLATLLLIRDIQARRLPYVAMASQTQGGNFSKGSWIGEMKQASDKTVIISEILDPRTKNLLSMSKISDYVLSNELVSMALAMVAEDRQINDVLEELFAEEGNEMHIRQADIYLREGEEMSFYEIMLRARQRREILIGYRLANAERAVINPPAKTGRRKWSLKDVFVVITEKE
What is the function of this protein?
Ion channel with a moderate preference for potassium over sodium and calcium.  Involved in perinuclear calcium spiking but not in cytosolic calcium influx.  Closed at negative voltages in presence of magnesium.  Required for early signal transduction events leading to endosymbiosis.  Acts early in a signal transduction chain leading from the perception of Nod factor to the activation of calcium spiking.  Also involved in fungal entry into root epidermal cells during the establishment of the arbuscular mycorrhizal symbiosis.
What are the official names of this protein?
Ion channel CASTOR.
What is the protein family that this protein belongs to?
Belongs to the castor/pollux (TC 1.A.1.23) family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Note=The chloroplastic localization proposed by PubMed:15616514 is probably an overexpression artifact.