PharMolix/UniProtQA huggingface dataset:
Protein: EPABA_XENLA
Sequence: MNATGAGYPLASLYIGDLHPDVTEAMLYEKFSPAGPIMSIRVCRDIATRRSLSYAYINFQQPADAERALDTMNFEVIKGRPIRIMWSQRDPGLRKSGVGNVFIKNLDESIDNKALYDTFSAFGNILSCKVVCDEHGSRGYGFVHFETHEAANRAIQTMNGMLLNDRKVFVGHFKSRRERELEYGAKVMEFTNVYIKNFGEDMDDKRLREIFSAFGNTLSVKVMMDDSGRSRGFGFVNYGNHEEAQKAVSEMNGKEVNGRMIYVGRAQKRIERQSELKRKFEQIKQERINRYQGVNLYVKNLDDGIDDDRLRKEFLPYGTITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVSTKPLYVALAQRKEERKAILTNQYMQRLATMRAMPGPLLGSFQQPANYFLSAMPQPPNRTFYSPNPVAPVRPAPQWASHQSRPPQYQPPTPLMRAVQPRRMSSNISTMKQASTQVPRVAQHSQRVANIGTQTAGARAQVNPSMMRTMPHYKYSCGVRNVQPIVSSTHLQQVMEPAVLMQGQEPLTASLLAGAPPQEQKQMLGERIYPVIHEMHPTLAGKITGMLLEIDNSELLHMLESPESLHSKVEEAVAVLQAHQAKENAQKSAQPSLI
What is the function of this protein?
Binds and protects the poly(A) tail of mRNA with or without an AU-rich element (ARE) and prevents mRNA deadenylation.  Stimulates the translation of mRNAs to which it is bound during early development.
What are the official names of this protein?
Embryonic polyadenylate-binding protein A, Embryonic poly(A)-binding protein A, ePAB-A, ePABP-A, XePABP-A.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with polysomes.
Protein: MSCL_NITWN
Sequence: MWKEFREFAMKGNVVDLAVGVIIGAAFGGIVSSMVADIIMPIVGAVTGGLDFSNYFLPLSESVNASNLSDAKKQGAVLAWGNFLTLTLNFLIVAFVLFMVIKGMNRLKRKDEAASAEPPKPTREEELLTEIRDLLKAKV
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_BACAH
Sequence: MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIEKADDLKTLEIPTNKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIKLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NU2M_NYCAE
Sequence: MNPLIFTMILLTVMLGTAIVMTTSHWVMAWIGFEMNMLAIIPILMKKYNPRSMEASTKYFLTQATASMLLMLAIVINLTYSGQWSMTKPLNSTASIIMTLAMAMKLGLAPFHFWVPEVTQGVQLSSGLILLTWQKLAPMSILYQISPTINLDLLLLMSILSILVGGWGGLNQTQLRKILAYSSIAHMGWMTAIMVYNPTMALLNLAIYILLTTTTFVMLMVDSSTTTLSLSHMWNKMPLLTTAILTIMLSLGGLPPLSGFTPKWMIIQEMTKNDSMITPTIMAVMTLLNLYFYMRLTYSTSLTMFPSTNNMKVKWQFNNKKLTANLSPLIILSTLILPLSPMLALLE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNLI_PICTO
Sequence: MDFSDVASYFSRMEETTKRLELTSILAELFKRSGDDLKKLVYLVQGKLMPDYLGIELGLSDKLIIKSLSKASGRSEEDINRIFSRLGDLGSTAEEISSSGIQRPLLKESLTVDYVYNQLIKISGYTGHGSIKTKMDAYIDLLINSGPMEIKYITRIITGKLRLGVADSTILDGLIEAFSEKKYADDIETAYNFHPDLGYIAENLMMGNINELLNAGPVPLIPFKVMLAERLQSISDIRNKMGHNASYEYKYDGLRTQLHFLKGGIKIFSRGLEETTSSFPDIVQNFKSYYSFDSCIIDGESVPYNPETGELYPFQMVSKRRGRKYELTEKTREVPIVMFIFDILYLNGKSLVNLPYPERRSILEKNFKENEYFKLAKRIVSDDEHDIMKFFERSIEEGCEGIVAKSNGIDSIYRAGARGWLWIKFKRDYQSELSDSLDLVVVGAFDGHGRRKGTFGALLLACYNSKDDTFETVCKLGSGFTDEMLSEMPRLLGDKIVEKKPARVNSSMEPDHWIYPSLVLEIRGAEITVSPVHTCAMNIIEKGSGLALRFPRLIKPRDDKKPEDATTTNEIIEMYKAQKKVIEKS
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: PYRG_SYNWW
Sequence: MTKYIFITGGVVSSLGKGITAASLGRLLKGRGLKVALQKFDPYINVDPGTMSPYQHGEVYVTEDGAETDLDVGHYERFIDENLSHYANCTTGRIYQTVLDKERRGDYLGQTVQVIPHITNEIKDRVTMIEKENSPDIVISEIGGTVGDIESLPFLEAIRQLKFDLGKDRVLYIHVTLIPYIEAAGELKTKPTQHSVKELRSIGIQPDILVCRTQKELSEDLKAKLALFCDVDREAVVQLPDAESIYEVPLMLAREKLDLEIIRRLGLECKQADLKEWKELASRVHRLDKEICIGLVGKYVELPDAYLSIVESLKHAGFQYNCEIKIKWIYAEKVEKEGAEELLQNVDGILIPGGFGERGIEGKIATAAYARENRVPFLGICLGMQCAIIEFARNVCQMKGANSSEFDPDSPYPVVHLMPGQENVANKGASMRLGGYPCRLVEGTLAYGVYGVSETSERHRHRYEINNEYRKEMESKGLVISGISPDGQLIEIIELKEHPWFVACQFHPEFKSRPNRPHPLFMGLIKGALDYKEEPDTASREG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RNH2_RICFE
Sequence: MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNTNIIPGIKDSKKLSKKKRELLYEQITSNYVWAAAIISHIEIDEINILEATKKACSIAAANLSLKPEIVLVDGNMPFKDKRFVSMINGDNLSLSIAAASIVAKVTRDRLMLDLSTEFPQYLWHKNSGYGTKEHIEAINMHGLSPYHRRSFKCC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIP_HUMAN
Sequence: MADIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH
What is the function of this protein?
Cellular negative regulator of the hepatitis B virus (HBV) X protein.
What are the official names of this protein?
AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_PORGI
Sequence: METFPHVFQYPFAVLQQQESGFPLRGRWHTDFFHNDHPIVLELGCGRGEYTVGLGKRFPEKNFIGIDIKGARMWAGAKESLQEGMSNVAFLRTDIELLDRFFAEGEVAEIWITFPDPQMKKVGKRLTGTRFLSLYDKVLERGGRIHLKTDSPFLYTYTKALVELNGLPVHEITDDLYGKGCVENEILGIRTYYEQQWLERGLTIKYISFGLGEPDCEYREPDIEIEPDSYRSYNRSRRSQAVPS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL4_SACS2
Sequence: MYLELVKKKSDILDKDGNRIKEVELPIIFSFPVRKDLIRRVFIAEFTHSLQPKGRDPNAGKRTSAESFGINLGMARVPRVKNSGEAALAPNTVGGRLAFPPSVNKKLAEEANVKEKRLAVISALSATADIAFVRARGHVFKDSVRFPIVVTDDIVNLKTTSEVEEFLKKIGVYDDVERVKERIRIRAGKGKMRGRKYKEPIGPLIIVHDSNSPIIKAARNLAGVDVVNAKDVSVIHLAPGAHPGRLTIYTESSIKILDERLSKRVVS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYL_SODGM
Sequence: MQELYRPEEIESTVQQHWHENDTFKVTEDPCKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYANIDYMKNQLKLLGFGYDWSREVTTCRPDYYRWEQWFFTRLYEKGLVYKKTSAVNWCPQDQTVLANEQVIDGCCWRCDTKVERKEIPQWFVKITAYADQLLYDLDKLESWPEQVKTMQRNWIGRSEGVEITFQVADSEETLTVYTTRPDTFMGTTYVAVAAGHPLSLQAAASNPALADFIQECRTTKVAEADMATMEKKGMATGLHAVHPLTGEMLPVWVANFVLMDYGTGAVMAVPGHDQRDFEFARKYDLPVKPVIRNADGSEPDLSAQAMTEKGVLFNSGEFDGLDFQAGFNAIADALVAQGVGERKVNYRLRDWGVSRQRYWGAPIPMMTLEDGTVVPTPEDQLPVVLPEDVVMDGISSPLKADPDWAKTTYNGQPALRETDTFDTFMESSWYYARYTCPDYDRGMLDPAAANYWLPVDQYIGGIEHAIMHLMYFRFYHKLLRDAGLVTSDEPAKRLLCQGMVLADAFYYLTSSGERVWVSPLEVSVERDEKGRIVKSTDASGRELVYAGMSKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWKLAYEHPQQGPVGALDIDALNDEQKALRREVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLARAPQQTGQDRALLQEALVAVVRMLYPFTPHACFTLWRALGGEGDIDNAPWPVADEAAMVEDAKLVVIQVNGKLRGRITVPADADEALVCERASQEHLVAKHLEGTTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM1_DANRE
Sequence: MPVRFKGISEYRSKYKGRTSRSRSDSPHRRMRLAGLRSDQSGITQEPQFISKRRVPFYPSQVSSSFRWEGRDHSQQQLEKSRSPAVSPVLRATSAERQVTPLAPRDPPEGTTAPSQPPQAEAAQTSTFAVQKQKQALNGINHALRMKAGLRSEHQRNGLNSEYQRQFMWKTPVAESPLLAAHQMLYSNNRAIPPFKTNPVIMESEYKRSFKGSPLPRPPRLRRDVEQYEVPEFLTESKTPEKSKRKKKKKERPHSRKSSPEQEVAYLQQQEVKSPHNLKDPSPKVMRKGKTEYRSNFHSPLQYSYKDGAWLKIKSAKEEVKELRERAEAYKKRAWGTHFSRQHLNQILSDQNWMWEPSSGTSSSSIESEACRSTSHIIEALDLARAGSVRESSSPGHSASVVVSRRSSSGEVGLPEEPTLPVQRKLAWDEEEQLGEREEIVQDRLTDKEGKTRNENGMERNERLNSLESESLSSAEEGSEASVNGGRLPTPKLKTMQTVQRTHHDRTTPSIDFNLHYIAKAANGSLPRSSPVAGLTTVDVLPMREDVWSDEEVTDYRSLKPPKPSRKQQSSQRHKANAAPPANRIQGTMRNAEFQHNGNLGIFRPELFVLPQSDSALSDNDDKMSQISSRSAASCSMASEVLGRAQRRKQEFWGKS
What is the function of this protein?
Microtubule-binding protein that negatively regulates centriole duplication.  Binds to and stabilizes microtubules.
What are the official names of this protein?
Nuclear protein MDM1.
What is the protein family that this protein belongs to?
Belongs to the MDM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the centriole lumen.
Protein: DCUP_NITHX
Sequence: MAQDSTIKPFLEVLSGRRQAVPPIWMMRQAGRYLPEYRELRAKAGGFLDLCFTPEFAAEVTLQPIRRFAFDAAIIFSDILVIPYALGRSVRFEVGEGPRLDPLDTPDMAATLSREADMTKLEPVFEALRRVRRELDSKTALIGFCGAPWTVATYMVAGRGTPDQAPARMMAYRHPEAFAKIIDVLVENSVRYLLGQLKAGADVLQIFDTWAGVLPPREFARWSIEPTRRIVEGVRKIVPDAKIIGFPRGAGALLPSYIEATGVDAVSIDWAAEPSLVREKVQSRVAVQGNLDPLALIAGGAALDRAVDDVLANFAGGRLIFNLGHGIQPETPIPHVEQMIRRVRGSGLRE
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKN1_SCHGR
Sequence: GNTKKAVPGFYGTR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-1, Scg-midgut-TK.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_STRSV
Sequence: MKIVIQRVKRAQVSIDQQLRSSIGQGLLLLVGVGPDDSQEDMDYAVRKIVNMRIFSDAEGKMNLSIKDIDGEILSISQFTLHADTKKGNRPAFVKAAPPEMASNFYDAFNLALQQEVPTRTGIFGADMQVELVNDGPVTIILDTKNR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDZN_BACSU
Sequence: MRWSKWFNVFCIVALGSIYGYKLFTNQEVSTTRLIIASVIVLWNIVGLFSKESVKQAQQAN
What are the official names of this protein?
Uncharacterized membrane protein YdzN.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_BORGP
Sequence: MNTVFNGKDFANKYYLILKEFLKQHDLRDKIALKVVLANNEPASKLYVSIKNRVAKEIGLNVEVIKFSANSVQSDILEVIDRENKNLSTDGIIVQLPLLRHMDSNSILNSIVYSKDVDGLSFVNLGKMILGDKKGFIPCTALAVLKILLDEGIRTSGKTVVVVGRSPLVGKPISILLSSKPYDATVIVCHSKSIYLDVYLRQADIVISAVGKPKLIDKSMLCGEPYVIDIGISEIETDNGKILSGDTDFDNIKDCVKFITPVKGGIGPVTVLMLMFNTIKAHLINNNMFDILDRLEKLVEV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL34_METM7
Sequence: MPAPRYKSGSSKKVYRKAPGNSSIVHYRRKKQSKAVCGACGALLNGVPRGRAVEITKLAKTQKRPERAFGGNLCPKCVKKMMVIKARNF
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: GLO2_WIGBR
Sequence: MNLVSISINEDNYIWLLYNNDKNCIIVDPGEFISIHNICKKKKLTPVAIFLTHHHHDHVDGVESLKTYFNTPVYGPKETIKYGTTKIVKEGDEIFLLNKCFKVFELPGHTLGHVGFYSPPWFFCGDTLFSAGCGRLFEGSAKDMYFSIKKINSLPPNTLICAGHEYTLQNLNFAISVFPKNTILSMYKKKVEKLNFYKKPTLPSALYLERQINIFLNPYNFEFKGELKRLLLQEEWVLFKKLRDMKNNFIY
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: LIPA_HAEIG
Sequence: MSTPFKMERGVKYRDAAKTSIIPVKNIDPNQELLKKPEWMKIKLPASSAKIESIKNGMRRHGLHSVCEEASCPNLHECFNHGTATFMILGAICTRRCPFCDVAHGKPLPPDPEEPQKLAETIQDMKLKYVVITSVDRDDLPDRGAGHFSECVKAVRELNPNIKIEILVPDFRGRVTQALEKLKDNPPDVFNHNLENVPRLYKEIRPGADYEWSLKLLREFKEMFPNIPTKSGLMVGLGETNEEILQVMQDLRDNGVTMLTLGQYLQPSRHHLPVARYVPPTEFDIFRDKANEMGFEHAACGPFVRSSYHADLQASGGLVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SALSV
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMVANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GCNT3_BOVIN
Sequence: MKMTGWKKKLCRGHHLWALGCYMLLAVVALRLSLRLKCDVDSLDLESRDFQSQRCRDVLYKNLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRLPFTDTYYLNITRDCEQFKAQRKFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVKAIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVPWKYLLNTCGTDFPIKTNAEMVLALKMLNGKNSMESEIPSEYKKNRWKYRYEVTDRLYLTSKMKDPPPDNLPMFTGNAYFVASRAFVQHVLENPKSQRLIEWVKDTYSPDEHLWATLQRAPWMPGSVPYHPKYHISDMTAIARLVKWQGHEGDVSMGAPYAPCSGIHQRAICIYGAGDLHWILQNHHLLANKFDPRVDDNVLQCLEEYLRHKAIYGTEL
What is the function of this protein?
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, C2GnT-mucin type, Mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase, bC2GnT-M, C2GnT-M.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: H2AY_RAT
Sequence: MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKQGEVSKAASADSTTEGAPTDGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNADFYIGGEVGSTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN
What is the function of this protein?
In contrast to isoform 1, does not bind poly-ADP-ribose.  Represses SOD3 gene expression.
What are the official names of this protein?
Core histone macro-H2A.1, Histone macroH2A1, mH2A1, H2A.y, H2A/y.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Enriched in inactive X chromosome chromatin and in senescence- associated heterochromatin.
Protein: MNME_XANCB
Sequence: MNASPSTIVAIATAAGTGGIGIVRLSGPQSVQIAAALGIAGLQSRHARYARFRDAQGEVIDDGIAVWFPAPHSFTGEEVVELQGHGSPVLLRQLVARCIALGARQARAGEFSERAFLNGKLDLAQAEAIADLIAAGDLRAARAARRSLDGVFSRRVDAVSESLTRLRIHVEAAIDFADEPLDTLGGAQVREELTRTRALLAQLLRDAERGRKLRDGLHAVLIGPPNAGKSSLLNALAGSDRAIVTDVAGTTRDTLHEAIQLDGFELTLVDTAGLREGGDAIEREGMRRARAELQRADLALIVLDARDPQAARDALGDAIDAVPRRLWIHNKCDLLAVAGPMDADAIAVSAVTGQGLEHLHTRLRELALGDGIESVDGEFSARTRHVDALHRAEQHADAADLELRYEQLELAAEELRLAHEALGEITGKLSADDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1717_ARCFU
Sequence: MRRMTDISPDKFAKAAEAIYEIFEKVVENHDEILDAIDKLLILERKGVFDEIVKFSEFKVPFTPDEIREIAERFEMLIKILLSVDERVLKVIKRLIDAFEESMVYEQMGMMEAMKALRDPDVQKAIGFALTLAKNFGKRI
What are the official names of this protein?
Uncharacterized protein AF_1717.
What is the protein family that this protein belongs to?
To B.subtilis YrhD.
Protein: CH60_ALIB4
Sequence: MAKEILFSDNARNRLYSGVEKLADAVKVTMGPRGRNVLLQKSFGAPTITKDGVSVAREIELKDTLENMGAQLVKEVASKTNDEAGDGTTTATVLAHSIFKEGLRNVTAGANPISLKRGMDKACEAILAELKKSSKVVANKTEIEQVATISANSDSAIGKMIAEAMDKVGKDGVITVEEAKGISDELDVVEGMQFDRGYLSPYFVTNPEKMIAEFNNPFILLYDKKISSLKEMLPILESVNQSGRPLVIIAEDVDGEALATLVVNRLRGSLHIAAVKAPGFGDRRKAMLEDIAVLTGGTVISEEMGMKLETAEFSCLGTASKIVIDKDNTTIVDGNGDNERVVARVNQIKAEISNTTSDYDREKLQERLAKLSGGVAVIKVGAATETEMKEKKDRVDDALSATRAAVEEGIVIGGGAALIKASKKVNLDLTGDERIGADIVLRAISAPLKQIAINAGFDAGVVANEVEKSSNENLGFNAATGEYVDMFEAGIVDPAKVERVAMQNAVSVASLLLTTEATVSDIKEDKPAMPSMPDMGGMGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_GEOSM
Sequence: MHQLVLLRHGESVWNKENLFTGWTDVELSPSGEEESRKAGLLLKEHGFVFDMAFTSLLKRAIKTLWIVLEQMDLMWIPERKEWRLNERHYGALQGLNKAQTAEQYGDEQVKLWRRSYKVRPPALAEGDRRHPSFDPRYHSLQGELLPSTECLQDTVERVLPFWRQQAVPALRQGKRILIAAHGNSLRGLIKYLDQVSDEDIVGLEIPTGSPLVYELDSDLKPMRHYYLETGKTG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RAPA_SHEPW
Sequence: MPFSLGQRWISDTESELGLGTVVGMEGRMVTVLFSATGENRLFSRSEAPLTRVIFNPGDKVESHDEWSLTVTEVEEKDNLIIYHGIHSETGEQASLRETLLNHNIRFNKPQDRLFAGQIDRMDRFGVRYQCQLLRNKLATSDLLGLQGPRVGLIPHQQWIAHEVGQRFAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILVIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADNDNPFYTEQLVICSLELLRKKKRLEQALDADWDLMVVDEAHHLEWSEDAPSRAYKVVEALSEVVPGVLLLTATPDQLGHQSHFARLRLLDPDRFYDYPSFLKEEESYKDVATAADALACGESLSSEAIASLTQLLSEKDISDSINLIQDASANADKRNQAREELLQELLDRHGTGRVLYRNSRASVKGFPTRNLHIHPQPMPEQYVTASRVSAMMNKHLDTNAKVRQVLSPEKIYQDFDSGSASWWKFDPRVDWLIDFLKTNRSKKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQETGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDVEIHLPYLAGTAQERLMQWYHQGLNAFECTCPSGHILFGEFSGELLETLTTDDESSLETLLDNTKSRYQELKVAMEQGRDKLLEINSHGGERANKLVESLAARDEDTQLIGSVIRLWDIIGVEQEDSGENAIVLHPSEHMMFPTYPGLPEDGITVTFDRDMALSRDDIALITQEHPIVQTGLDLITSSETGTTSVAVLKNKALPAGTVFLELIYMADASAPKSSQLYRYLPPTPIRILLDKSGNNLSDNVTYESFDRQLSAVNRHIASKLVTASQAILHPLFAKGETFAANELKLLTETAREKMTQQLTGELERLKALKAVNPNIRDEELTHLSEQMSELNRYLDSSQLQLDAIRLVLVSHA
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: HIGA_PROVU
Sequence: MRQFKVSHPGEMIARDLEDMGVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAALGSTPEFWLRLQSNYDLRQLENQIDTSGIVLYGESNEQQQNAQEH
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system that counteracts the effect of the HigB toxin (PubMed:19423702, PubMed:8645296, PubMed:24257752).  Binds to its own promoter and regulates transcription of the higB/higA operon (PubMed:24257752).
What are the official names of this protein?
Antitoxin HigA, Antidote protein, Host inhibition of growth protein A.