PharMolix/UniProtQA huggingface dataset:
Protein: OPGG_SODGM
Sequence: MPNNKFFVKSSKASLRWLGATVLLTLYALPSWAFSIDDVAKQAQALAAKGYEAPKSNVPSQFREMKFADYQQIQFNHDKALWHDLPTPFKIEFYHQGMYFDQAVKINEVTATAVNEVKYSSDMFNFGSVNHDPDAVKDLGFAGFKILYPINQLDKNDEIVSMLGASYFRVIGKGQVYGLSARGLAIDTALASGEEFPRFREFWIERPKANDKHLVLYALLDSPRATGAYRFVIYPGRDTSVDVQSRVYLRDKVGKLGLAPLTSMFLFGPNQPAMTMNFRPALHDSDGLSIHAGNGEWIWRPLNNPRHLSVSTFQVENPRGFGLLQRGRDFFQYQDLDDRYDLRSSGWVEPRGDWGKGHVELVEIPTNDETNDNIVAFWTPEKLPDVGQPLELAYRLHFSRDEDKIHSADFAYVKQTLRSAGDVKQTNLTRQPDGTTAFQVDFVGQPLKELDQAAPVTSQISVGDNADVVENSVRFNPVTHGWRLTLRLKVKDTKQPTEMRAALVNGDKTLTETWSYLLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNF25_HUMAN
Sequence: MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity).  Stimulates transcription mediated by NF-kappa-B.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF25, RING finger protein 25, RING-type E3 ubiquitin transferase RNF25.
Protein: PLAS_SAMNI
Sequence: VEILLGGEDGSLAFIPSNFSVPSGEKITFKNNAGFPHNVVFDEDEVPSGVDSAKISMSEDDLLNAPGETYSVTLTESGTYKFYCSPHQGAGMVGKVTVN
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: PHLA3_HUMAN
Sequence: MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSLGTGTLVS
What is the function of this protein?
p53/TP53-regulated repressor of Akt/AKT1 signaling.  Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation.  Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity.  Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1.  May act as a tumor suppressor.
What are the official names of this protein?
Pleckstrin homology-like domain family A member 3, TDAG51/Ipl homolog 1.
What is the protein family that this protein belongs to?
Belongs to the PHLDA3 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: SYF1_USTMA
Sequence: MPPKMRSSQENVAVSSDATIQASSASSPLQDAMAAVTSLFPLTSPFPDPAKDDTLIPAADILLEQELLRNPDNFRSWSSYIDHIINTNVVKRPPPDVSLTTYQAALLGPLASSTQRTALRRLTSIYERALAQFPTRYSLWRDYLQNRSRFVLGDPKGGSDAKRKRDLQAAREKLDFGPTLIDSVEDEDFGSAYRGGLDGTVGWQEWKSLAALYERALMWLPTMPRLWLSYLSMFIHPQCPPILSFTHARRTFDRALRTLPGSLHLRVWKVYLKWAERRGGETCLRVWRRYLRVDPSLTERYVSILLAQREDQDEPEGEEEEAEDDAQSDRSRKQSGSKALEASKLLLGLARSAMDGTYVSPEGKSPFQLFVEWLELTEKYPEEIGLDPEEEKKYLQHSVALTSDNGMTNARRAPRHIQGKGTAAREIAKASSSKHPETDALDPTRLNVTAIIQKDGLDKFSDQSGRLWTGLATYWIKRGEFDVARDTFEAGIQTVKTVRDFTQIFDAYAETSENVIAFMMDELTEEGGDEEADAEDQEETREDKEAELDRRMQEFEELIERRPLLVNDVLLRRNPDDVQEWEKRVMLYGDNDEKIIETYREAIQKINPRKATPNFHQLFLNFAQFYEYGGSAGLAKRMAEGVEGQEEEEQAEQVEGDLESARKIFEKAITIPFRRVDDLAEIWCEWAEMELRHSNYDEAIRTMARSVAPPRNTKGIQYHDDTLPPQTRLFKSLKLWSFYVDLEESLGDVESTKRVYEKMLELKIASAQIIINYAAFLEDNKYFEESFKVFERGVELFSYPVAFEIWNVYLSKFVKRYGGAKLERARDLFEQALDKCPARFCKPLMLMYGQLEEEHGLVKRAMKIYERATRAVSTDDRFDMYVFYIAKAAATFGLAATRPIYERAIESLPDRQTAEMCLRFAALERKLGEIDRARVIYAHASQFCDPRTQTDFWKEWNQFEIETGSEDTFREMLRIKRSVQAQFNTDVSYIAASALASAQQNQAQRGAQGSSNGHVREDDVDASDPMARVEAASRSAGARQTAFVAASTAASGARSADTTIGDVAKNDEVVGGDDQDDQDLL
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LCA5_RAT
Sequence: MGERDQSSDTDQERKGGKHPYSSHYSSDFGSSPQSSGPSSPVNTPPCASNREKNPKRHLSDHHVRHQTVRKVSPKAIPNKKGVRVGFRSQSLNREPLRKDPDIVTKRVLSARLLKITELQNEVSELQVKLAQLLKENKALKSLQYRQEKALSKFEDAENEISQLIHRHNGEITALKERLRKSQEKERMAEKRVKDTEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDNTERKIKELSKNLELSTNSFQRQLLAERKRAFEAHDENKILQKELQRLHHKLKEKEKELDIKNIYANRLPKSSPKKEKEIARKHASCQSDFTDLCTKAVQTAEDFEPEEFPFTAQTVLCYENRWDGSEYLPSYLEYQERNEHGSESLSSTLEQEGKYSDDQDSCTAKQETGKSECEWEREELDKVKGKSSLLGRTEKLVLEAGSVQTESYQAQTIDKFQDEAERLKTEMLLAKLNEINKELQDPQSLSRPLLPLLPNFESKLYSPDRSLRPYTFSESLDRSFNGQHLSDMSFLTPRDEGQSPGLIRSPAPSDEFSFGSYVPSFGKTPGKSNPPSQKNSLLDFQSNMSEGLSKDSLDFISRKEKKATLMEQLFGTSASASATNTSASTTTNTTTNTNTNTNTNTNTNCNVPSKSIDSHFPAASRGDLDPLHFLSGDRSSRVREPDGEDEDLFLSEGRSFNPNRHRLKHTSTKPTVTAVDSIDEDIEEVTLR
What is the function of this protein?
Involved in intraflagellar protein (IFT) transport in photoreceptor cilia.
What are the official names of this protein?
Lebercilin, Leber congenital amaurosis 5 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LCA5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Localized to the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium.
Protein: FB128_ARATH
Sequence: MAEADDGGNGDGATAGDCYAHHHYRDVKLARDASENIDSISSLPDVILQQILSSLPTNLAIRTSVLSTRWRHVWSDTPYIYFDGPGTLYRGLKADTINKTLARYKLPKIMSFHLYTKIF
What are the official names of this protein?
Putative F-box protein At2g39415.
Protein: RRS1_CAEBR
Sequence: MADKSTEVEKAIDPIIDLGNLLFIDREPLQGDAEEGLEERARKNTQLLFNNIWQLEQKRVEEAIIVTLPAATYRLPREKKLPEKKEPTKWEKYAKEKGIEKRKKDKKVFDEATKEWKPTYGYRRGNDNTKDWLIEIPDNAEDPNKDFFAERREKKKERVAKNEMQRMKNLARQMKTTVKTGPSTDKMIGVGIDAKDKSKQDVRFAVDRAKLATASAGKFQEGLKGEKANIKTGKKRKFESNEAPVSAEKERALQILQRMKSKKAKIVEEKASAVAGPLREKKEKQEKKGAKEATRQKSQIHRQQWFKNKVDSKKKGTGGAKKKGANKRK
What is the function of this protein?
Involved in ribosomal large subunit assembly.
What are the official names of this protein?
Ribosome biogenesis regulatory protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RRS1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FPG_MYCBT
Sequence: MPELPEVEVVRRGLQAHVTGRTITEVRVHHPRAVRRHDAGPADLTARLRGARINGTDRRGKYLWLTLNTAGVHRPTDTALVVHLGMSGQMLLGAVPCAAHVRISALLDDGTVLSFADQRTFGGWLLADLVTVDGSVVPVPVAHLARDPLDPRFDCDAVVKVLRRKHSELKRQLLDQRVVSGIGNIYADEALWRAKVNGAHVAATLRCRRLGAVLHAAADVMREALAKGGTSFDSLYVNVNGESGYFERSLDAYGREGENCRRCGAVIRRERFMNRSSFYCPRCQPRPRK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GRDI_PEPAC
Sequence: MKLELGNFYVEEIVFGEKTSFKDGVLTINKQEALDYVMEDENITHAELHIVKPGDMVRLCPVKEAIEPRIKLDGRTYFPGVTDEELTRCGEGRTHALKGCSVLVVGKHWGGFQDGLIDMGGEGAKYTYYSTLKNIVLVGDTNEDFEKNEQQKKNKALRWAGHKLAEYIGKTVKDMEPQEVETYELEPVTQRSEEVTKLPGVVFVMQPQSQMEELGYNDMVYGWDMNRMVPTYMHPNEVLDGAIISGSFMPCSSKWSTYDFQNFPALKRLYAEHGKTVNFLGVIMSNLNVALQQKQRSALFVAQMAKSLGAQGAIVAEEGYGNPDADFIACIVALENEGIKTVGLTNECTGRDGFSQPLVTLDEKANAIVSCGNVSELVELPPMPVVLGELEALARDGLSGGWAGDEILGSSVKADGSVIMENNAMFCGDQVVGWSTKTMKEF
What is the function of this protein?
In the first step of betaine reductase, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
What are the official names of this protein?
Betaine reductase complex component B subunit alpha, Selenoprotein PB alpha.
Protein: NU2M_MOLAE
Sequence: MNPLIMTTILTTVILGTLIVMMSSHWLLIWIGFEMNMLAIIPMLMKQHNPRSTEAATKYFFTQATASMLLMLAVLLNLMYSGQWTVMKLYNPTASMIMTMALTMKLGLAPFHFWVPEVTQGIPLSSGLILLTWQKLAPLTVLYTISPNINLTMLLTMSIASIAIGGWGGLNQTQLRKIMAYSSIAHMGWMTTILIYNPTMTLLNLVIYILMTTTMFMLFMTSSSTTTLSLSHMWNKTPMIVTITLATLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTIMAITALLNLFFYMRLTYATSLTMFPTTNNMKIKWQFENPKRLSLLTPMIVLSTLTLPPTPMIIILN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LPAR1_SHEEP
Sequence: MAAASTSSPVVSQPQFTAMNEPQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTTVTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENTSGPTEGSDRSASSLNHTILAGVHSNDHSVFRKETKMRGGHHLLRDEQPPPPERPGQGRV
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA).  Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents.  Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins.  Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels.  Signaling triggers an increase of cytoplasmic Ca(2+) levels.  Activates RALA; this leads to the activation of phospholipase C (PLC) and the formation of inositol 1,4,5-trisphosphate.  Signaling mediates activation of down-stream MAP kinases.  Contributes to the regulation of cell shape.  Promotes Rho-dependent reorganization of the actin cytoskeleton in neuronal cells and neurite retraction.  Promotes the activation of Rho and the formation of actin stress fibers.  Promotes formation of lamellipodia at the leading edge of migrating cells via activation of RAC1.  Through its function as lysophosphatidic acid receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding.  Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14.  Promotes cell proliferation in response to lysophosphatidic acid.  Required for normal skeleton development.  May play a role in osteoblast differentiation.  Required for normal brain development.  Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus.  Plays a role in pain perception and in the initiation of neuropathic pain.
What are the official names of this protein?
Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Multi-pass membrane protein. Endosome. Note=Prior to LPA treatment found predominantly at the cell surface. Internalized after LPA treatment. Colocalizes with RALA in endocytic vesicles after LPA treatment.
Protein: FTHS_STRPJ
Sequence: MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDKIRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRRILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRRLANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIAHGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRALKMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVLKELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEKIVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEITIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CCRM_BRUO2
Sequence: MRSQVIEYPMSLVRLAHELPIEAPRTAWLDSIIKGDCVSALERLPDHSVDVIFADPPYNLQLGGDLHRPDQSMVSAVDDHWDQFESFQAYDAFTRAWLLACRRVLKPNGTIWVIGSYHNIFRVGTQLQDLGFWLLNDIVWRKTNPMPNFRGRRFQNAHETLIWASRDQKGKGYTFNYEAMKAANDDVQMRSDWLFPICTGSERLKDENGDKVHPTQKPEALLARIMMASSKPGDVILDPFFGSGTTGAVAKRLGRHFVGIEREQPYIDAATARINAVEPLGKAELTVMTGKRAEPRVAFTSVMEAGLLRPGTVLCDERRRFAAIVRADGTLTANGEAGSIHRIGARVQGFDACNGWTFWHFEENGVLKPIDALRKIIREQMAAAGA
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-GANTC-3' and methylates A-2 on both strands (PubMed:12654995) (By similarity).  CcrM-mediated methylation has important cellular functions.  Contributes to the accurate cell-cycle control of DNA replication and cellular morphology (By similarity).
What are the official names of this protein?
DNA methyltransferase CcrM, M.CcrM, Adenine-specific methyltransferase BabI, Probable type II methyltransferase M.BovORF495P, M.BovORF495P.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RL1_FLAPJ
Sequence: MAKLTKKQKEAVSKIEKNKLYSLKDASVLIKQIASAKFDESVDIAVKLGVDPRKANQMVRGVVALPHGTGKNMRVLALVTPDKEAEAKEAGADFVGLDDYLQKIKDGWTDVDVIVTMPAVMGKLGPLGRILGPRGLMPNPKTGTVTMEIGKAVTEIKAGKIDFKVDKTGIVHAGIGRISFDADKIMENAHEIIQTLIKLKPTAAKGTYIKSIHLTSTMSPAIALDPKAV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ATE1_MACFA
Sequence: MAFWAGGSPSVVDYFPSEDFYRCGYCKNESGSRSNGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMNQTCCPQYTIRCRPLQFQPSKSHKKVLKKMLKFLAKGEVPKGSCEDEPMDSTMDDAVAGDFALINKLDIQCDLKTLSDDVKESLQSEGKNSKKEEPHELLQSQDSVGEKLGSGEPSHSVKVHTVPKPGKGADLSKPPCRKAKEIRKERKRLKLMQQNPAGELEGFQAQGHPPSLFPPKAKSNQPKSLEDLIFESLPENASHKLEVRLVPASFEDPEFKSSFSQSFSLYVKYQVAIHQDLPDECGKTEFTRFLCSSPLEAETPPNGPDCGYGSFHQQYWLDGKIIAVGVIDILPNYVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMKYKGQYRPSDLLCPETYVWVPIEQCLPSLENSKYCRFNQDPEAVDEDRSTEPDRLQVFHKRAIMPYGVYKKQQKDPSEEAAVLQYASLVGQKCSERMLLFRN
What is the function of this protein?
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein.  This arginylation is required for degradation of the protein via the ubiquitin pathway.  Does not arginylate cysteine residues (By similarity).
What are the official names of this protein?
Arginyl-tRNA--protein transferase 1, Arginyltransferase 1, R-transferase 1, Arginine-tRNA--protein transferase 1.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LGT_AGRFC
Sequence: MIAAPTQLAIMPFPNIDPIALSIGPLAIHWYGIAYVAGIMLGWFYARRLARTDRLWPNDTSPISAQHLDDFILWAAGGIVLGGRIGYILFYDMAAVAANPIRAIEIWNGGMSFHGGLIGTTIAMILFARRNGIPVWSMFDIIAAVAPIGLLFGRIANFINGELWGRIADVPWAVVFPTGGPFARHPSQLYEAGLEGLVLVVLLAIAIYVFKALKTPGTVTGIFVCGYALSRIFVEFFREPDAQIGYLAGNWLTMGMVLSTPMFLLGLWAVLRARSATKSA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLCB_SALDC
Sequence: MFRRLLIATLIGILAALAVAAFRHAMQLLEWIFLSNDTGSLVNAAEGLSPWRRLITPALGGLAAGLLLWGWQKMNQQRPHAPTDYMEALQTDGQFDVGASLVKSLASLLVVVSGSAIGREGAMILLAALAASSFARRFTPREEWKLWIASGAAAGMAGAYHAPLAGSLFIAEILFGTLMLASLGPVVVSAVVALLTTHLLNGSDSLLYTVHLTVDLHAREYVMIVSTGLVAGLCGPLLMWLMTASHNSFLRLKLSPPWQLALGGLIVGLLSLLTPTVWGNGYSVVQSFLLSPPLFSLIGGIFACKILAVLASSGSGAPGGVFTPTLFVGLSIGMFLGRIWGFWLPGSDEIAILLGLAGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVVASVLSRTLRHDSIYRQHAAEH
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTPA2_YEAST
Sequence: MLPEKRLLTPDDMKLWEESPTRAHFTKFIIDLAESVKGHENSQYKEPISESINSMMNLLSQIKDITQKHPVIKDADSSRFGKVEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQLSIYLDESWGNKRRIDYGSGHELNFMCLLYGLYSYGIFNLSNDSTNLVLKVFIEYLKIMRILETKYWLEPAGSHGVWGLDDYHFLPFLFGAFQLTTHKHLKPISIHNNELVEMFAHRYLYFGCIAFINKVKSSASLRWHSPMLDDISGVKTWSKVAEGMIKMYKAEVLSKLPIMQHFYFSEFLPCPDGVSPPRGHIHDGTDKDDECNFEGHVHTTWGDCCGIKLPSAIAATEMNKKHHKPIPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for TAP42-associated PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.  Acts also inhibitory at high concentrations.  Involved in the regulation of cell cycle progression, mitotic spindle formation and bud morphogenesis.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_ACTPJ
Sequence: MDSSNAIFKSFLGKAPEWYKICIIAFLVINPLIYFFISPFVAGWALVAEFIFTLSMALKCYPLQPGGLLAIEAVFIGMTSAHHVKEEIMANFEVILLLMFMVAGIYFMKQLLLYVFTKLLIVIHSKKILSLAFCLSATFLSAFLDALTVIAVIISVGTGFYGVYHKVASGNSFEDSTDISNDEKIITNKEILEQFRAFLRSLLMHAAVGSALGGVMTMVGEPQNLIIAGQAEWGFVEFLLRVLPVSLPVLICGVITCLLLEHFKIFGYGARLPRRVWGVLARYNLLKEQRMTQQDRVKMGIQALAGIWLVVGLALHLADVGIIGLTIIIICTAFCGITDEHAIGRSFQEPMPFTALIVVFFTVVAVIVDLKLFEPIISYVLSADPHSQLALFYVFNGLLSMISDNVFVGTVYINEAKTALESAIISREQFDLIAVAINTGTNLPSVATPNGQAAFLFLLTSPFAPLIRLSYGKMLYMALPYTIVLSIIGFLSLEFLLPPLTELMSNWGWIITR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PQQA_ACIAD
Sequence: MWTKPAFEDIRLGFEITMYAAVE
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: TSAD_SHEDO
Sequence: MRVLGIETSCDETGIAVYDDKLGLLSHKLYSQVKLHADYGGVVPELASRDHVRKIVPLIKQALLDANTSANELDGVAYTKGPGLIGALLVGACVGRSLAYAWGKPAVGVHHMEGHLLAPMLEDDAPEYPFVALLVSGGHSMLVKVDGIGRYEVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLASEGVPAGYKFPRPMTDRPGLDFSFSGLKTFTANTIMAEPDDHQTRANIARAFEEAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAELMTSLGGRVYYPRGEFCTDNGAMIAYAGLQRLKAGQVEDLSVKGQPRWPLDSLPAVD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHN_PROM0
Sequence: MPLLLTGKKFHNDLKTNKCLAIFAPLEGGYETRLLRRMRAKGFKTFITSARGLGDPEVFLLKLHGVRPPHLGHQSVGRNGALGEVQQVIPQASELFNENDKNKLLWLLEGQVLSQSELESLIEICTKDNKLTIVVEMGGSRKLEWKSLSNYILDEFEN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DAPA_CHLTE
Sequence: MSNRLISGSAVALVTPFHQDGSIDFEAMRRLVRFHREAGTDIVLPCGTTGESPTLTNEEEAEIIRVVCEEAGESMMVAAGAGNNDTRHAIELARNAEKAGAQAILSVAPYYNKPSQEGYYQHFRHVAEAVSIPVIIYNVPGRTGSNVNAQTILRLARDIENVVAVKEASDNFEQIMTLIDERPENFSVMTGEDGLMLPFMALGGDGVISVAANQVPKVVKGLIDAMKAGNLEEARAINRKYRKLFRLNFIESNPVPVKYALSLMGMIEEVYRLPLVPMADANKAILRAELEKLSLV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_LEUMM
Sequence: MARSLKKGPFADPHLLKKIEAQVDSEKKSVIKTWSRRSTIFPSFIGFTIAVYDGRKHVPVYVQEDMVGHKLGEFVPTRTFKGHKNDDKKTGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.