PharMolix/UniProtQA huggingface dataset:
Protein: SEPT6_MOUSE
Sequence: MAAADIARQVGEDCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVGLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHSYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPVIAKSDAISKSELAKFKIKITSELVSNGVQIYQFPTDDESVSEINGTMNAHLPFAVVGSTEEVKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQEEKKKLEDKKKCLDEEMNAFKQRKAAAELLQSQGSQAGGSQTLKRDKEKKNNPWLCIE
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Required for normal organization of the actin cytoskeleton.  Involved in cytokinesis.  Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).
What are the official names of this protein?
Septin-6.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cell projection, cilium, flagellum. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. Found in the sperm annulus (By similarity).
Protein: TXC13_CUPSA
Sequence: MKVLVIFAVLSLVIFSNCSAETDEDFFGEESFEADDIIPFIAKEQVRSDCTLRNHDCTDDRHSCCRSKMFKDVCTCFYPSQRSETARAKKELCTCQQPKHLKYIEKGLQKAKDYATG
What is the function of this protein?
Synergistic toxin that induces or increases a cytolytic effect when combined with CSTX-1 (AC P81694) or CSTX-9 (AC P58604).  When alone, has a weak insecticidal activity, with an unknown molecular target.
What are the official names of this protein?
Neurotoxic enhancer CSTX-13, U2-ctenitoxin-Cs1a, U2-CNTX-Cs1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 12 subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RSMA_YERPY
Sequence: MNNRVHQGHFARKRFGQNFLNDQFVIDSIVSAIHPVPGEAVVEIGPGLGALTEPVAARMDHMTVIELDRDLAARLASHPQLKDKLTIHQQDAMKVNFSELSEQAGQPLRVFGNLPYNISTPLMFHLFSYTDAIRDMHFMLQKEVVNRLVAGPNSKAYGRLTVMAQYYCNVIPVLEVPPTAFTPAPKVDSAVVRLIPHVQMPHPVGDVRMLSRITTQAFNQRRKTVRNSLGDLFTSEQLIELGIDPILRAENISVAQYCKLANWLSAQSTPQK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_STRPD
Sequence: MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVVRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CSRA_BORBZ
Sequence: MLVLSRKANESIKINSDIEVLILEIKKDAVKIAIKAPENIKIFRSEIYEFIIEENKKSLLKDKHNISKIKSLFNHYFKNEN
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHB2_HUMAN
Sequence: MAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEQAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAGLYGQQPANQVIIRERYRDNDSDLALGMLAGAATGMALGSLFWVF
What is the function of this protein?
Involved in retrograde transport of recycling endosomes.
What are the official names of this protein?
Pleckstrin homology domain-containing family B member 2, PH domain-containing family B member 2, Evectin-2.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR.
Protein: STXA_ANEVI
Sequence: MMNRLLVFLMLGAFMLVVSANDAYGGDESLGKRKSCCPCWLGGNCFWGQNCYPQGCSGPKV
What is the function of this protein?
Sodium channel inhibitor.  5 uM completely inhibits voltage-gated sodium channel (Nav) inactivation.
What are the official names of this protein?
Delta-actitoxin-Avd2c, Delta-AITX-Avd2c, Av10, Neurotoxin 10.
What is the protein family that this protein belongs to?
Belongs to the sea anemone short toxin (type III) family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: ARHGJ_MOUSE
Sequence: MDCGPPATLQPHLAGPPGTARRPVAVCQQESLSFVELPPSRLCVDLFPIAPEELQAPGSRWSLATPAPLQGLLWPTSPGGPDTHIASTSGGMRPGRAGSWPHCPGAQPPTLVEPWSSQHMQPQRRASHSGSEKSAWRKMQVYHNEEATGTETPTGLLETGQAAQEQALCALEPGPQELSGNARGGLEAPERRRFSASELMTRLHSSLRLGRSTATRVLTSGSGAGAIREGKLPVRESRRAETRADSVSLPGPVDLNEVHGGLVEPRLDTQDKPTQDPSSATERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDGAEGAEEGPGPPRANLSPSSSFRAQRSTRGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSVELSECLGTQDKQWLFSKLPEVKSTSERFLHDLEQRLEADVLRFSVCDVVLHHCPAFRRVYLPYVTNQAYQERTYQRLLLENPKFPGILARLEESPVCQRLPLTSFLILPFQRVTRLKMLVENILKRTAPGSQDEDMATKAFSALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHANMAELQVRDLSLKLQGIPGHVFLLRLLHGQRARHQLLLRARTESEKQRWISALRPSSPQEDKEITCDGEDRPQVQCVRTYKALQPDELTLEKTDILAVKTRTSDGWLEGVRLADGEKGWVPQAHVVEISSLSARLRNLREYKRVSNASSKLGDPPA
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 19, Ephexin-2, Weakly similar to Rho GEF 5.
Protein: PSD2_KOMPG
Sequence: MSQAFNLVLFTEIKQAQNVKTGNDKEPNSKLRAIVRISERSSKKTPRATPRDDFVYTWNSTISLKLRSQLKLPLIQISVWDKQAHRSVYVGEVRFFLIGLLKSLAYNEHTSSWESTPQWYQLYSSEDKKSFSSGTILVQFRVQQHLSKKNLFFNAKSDVTLSDQTGSSDLLNQYIQAIETSTPRSLQKKAFDLSNPNEQRFYPDIETNALASSILDCEIDSMLEDFTYRKPNITESSLHDDTLTDTDFESIHSDPTIPSSALVPKRILFIEILSVTDLPPYKSFTRATFDMDPFVVISFGKRTYRTSWRKHTLTPVFNERLAFEVCDYEKNYDLQFSVLDKDKFSFHDQVATGFVSVSELLEEKTTDKPCTDFKPTSSNLILLDKPMNANESADNLLDTKKKKYKRNVNTDATLQGGLLRKYELVMSLDGKKNWSRKTKDEYIPILKFNTRFERYEILRRQLWMHLLQGNDTQMKGTLDLIELNYFVDCLGSNLSDKTLASFFEYYDKNPWVGETLTIEQVIDSLERLVFKRQCANTHENYIINIDTCPLCGQGRLSLRQDLDILKHLSICASRDWSTVNKVLKPSFVSSKAATRRWYSRLLIKLTFGQYTLGGNSANILIQDRDTGYILEEKMNIHVRLGIKLLYKSFDKANSRKIKTLLRKLSIRQGIKFDSPSSVSQIPSFIKFHKLDVDDCLLQLDEYKTFNEFFYRKLKPGSRPQEDENNSNIATSPADCRCTVFESITFAKTFWIKGRNFTTKKLFGSFYSREMADLYDECSIGIFRLAPQDYHRFHSPVTGTVGKVQSISGEYFTVNPMAIRSDLDVFGENVRCLLPIQTKEFGRVLVVPVGAMMVGSIILSVKENQEVKKGDELGYFKFGGSTLLVLFPNKRFKFDSDLLANSNNKIETLIKVGMSIGHTPEEPQFERHYRSFEEEPVDQQLRIIRCITGGSTFEESKQATQRRNELLGNEGSPQEKDLQVENLSWEAKNMNLEELEENESLLLYDLVNDGT
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 2.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOC1_OEDCA
Sequence: MIKKNLFKDFSRFSFVQSSIKNNVRCHSKLKLVQPFFIKTKQERNKKFLSSYKFSEIQLITIDLASPEKIKEWAEKKLPNGKIFGQVTNPNTLHYKTLKPLKGGLFCERIFGPIKDFECACGIQKQKPFNRIISFQNKQFCSKCDIEYTWSDIRRYQLGYIQLVTPVTHLWYLKGMPSYIRSVLGAKKKHIEAIAYCSEIVTIDQAWKPNRLIPFPETISSVALSSKKRNTFVNKEIVNIQLTYNNFKKFNVNNTRSLYVSINKKLFKKQFSNNSYNCTCVDNEIQNPIFFLKYFNINFLKPQNLKELKVLYINPDFYKVENYPYKNQVKFEFYQKICRSFIKTSLNNHKPIYALNYLSHSFLNSKVKIFSHFEHIDIHTMYVFNEEILINRFSNLARLKKNGKSKKKIGYIHSKKIHININKHLLYFKNKKLKNLQLSNNLKLIIIISNNASLNYFKNWSNTFNCMNTLILKMQFVNKKLHFQYYRSFFNTHTIERVYFNFFSLDYLKNSNFFVNFSKLLALNLLKFMKSNLFNIFIIPIPTILDNFIFKLSLDSQFQRLLNSLSIQKQKVLNSNSVISKSNKIFKKQFFIKNFSLYDEAIEILWQRFWKFGYYFTSNNMNNKLCKIITKFNKNNNGLRSTLPSWLKLIKKLIKKTQIDKKSNQNLLNFRVNVIHTNTQNKFSLFVNLIKIYLKKVLFLFQIAPENIKNIYIKKSIFIFQELRNKNFKYRNFRTQIKKIVIKLFGLELLPWVLSQFIFTSKIFYQFQKSKFSFYHNSNFLTFSRRHSGRNLIKKIKESSFLNFQIGVNNINTIFHYKYSFNCLPSCHIPNYKCRQKFFIYKNKIENILKLKKFRLFFNIWLSRFLKNNISVLNVVVNLKLNNINSNNLQTLNLLFYQKKWLLKKKQIFYNYAMLKEFHSKLLIVGTLHDFSNFIKLIYSSSYKNETLINIFSIQIQPFYKFNFIQKIRKYLNSEYYNSFDSGRTKHYLRKFLNKDSDNLFFKQFNYVYYFILFSSIISTQTIERGSLTSLNNQQFFLNLLCFFKLAKKNIFKKYSWLTSIQKYFYSRQIIKYKKKQQQKSMLKFVKKKTFFNKFLDLINSFIYDYQKRLKLLKKHSIIQLILKKKMYIFYFLKKLQNKLINEIQKYYFYEFEKKKFINIEFNLNNFKNIVIFMNLKKKILFLNSVLFQSQTNFFNKHANLNIFNNSYNYMYIDFNNFLSIGQFWQILINIFKNKINKYYLLSRSLPFIISNDYVKIDPLIKKFHDDLKHQVCFNSFLIKLTFYNSTLLYPLQNIIKNNNKVLQTRQQYYKIIKSNNLFLTNYFKKIRGNFTELSIKKFENIHTIVSCIGYFGYQDILYHQIRELKKNDYFRNFYLKFIKHDLSNNFNEAIFSVISESRISYNDSIFWNNIYSLSNRYSWKSDIELNIFLCYMLSPETPSDILIPLYKQRIHSSNVLREEPPIAGGGIILKLLKELDLPEMKKIDIQLQTILKKIPNKLHEIEVLLKHNQTNLKLLKYYSLKRRTVIEIEKSILRKLKYIRRLNWVSAKPEYMIIRNLPVLPADLRPIFKIQQQLTASDLNRLYQKVIYRNDRLKRFLKNSTTSNSFEMLFAQRMLQEAVDNLIENGKDINSIETDSRGRPLKSLGELLKGKKGRFRQNLLGKRVDYSGRSVIVVGPKLKLHECGLPIEMAIELFLPFLIKEILKNKYALTVRSAKIYIKKHRIKITQLLRQVVKRQPILLNRAPTLHRLGIQAFLPKLVEGKAILLHPLVCSAFNADFDGDQMAVHVPITNEARIEAWKLVLSRNNLLSPATGEPILLPSQDMVLGCYYLTIENLQSLTQKKFRINRKILNQRNYIFSDFEKIFIAYQRNQINLHTNIWVIFNNTIESDSILQEPTEIQVLFSGQYIKVYSDYYQKFNRNGKIYNQVVRTTPGRILFNLMLNNCFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIC12_VANPO
Sequence: MSKIWKFTSFATISSVAAASLYLYAIDKNGYYYEKSKFKQVTDRVRKLIDGDETFKYVTIDDFVSGPTQIQTRSRGETFKDLWNAEVRRTAQWIYSLGGR
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC12, Altered inheritance of mitochondria protein 5, mitochondrial, Found in mitochondrial proteome protein 51.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic12 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RK2_MORIN
Sequence: MAIHLYKTSTPSTRKGAVDRQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKDIYGKIVTIEYDPNRNAYICLIHYGGGEKRYILHPRGALIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLIPKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SWAHC_HUMAN
Sequence: MEGPAEWGPEAALGPEAVLRFLAERGGRALHAELVQHFRGALGGEPEQRARARAHFKELVNAVATVRVDPADGAKYVHLKKRFCEGPSEPSGDPPRIQVTAEPEAPDGPAGPEARDRLPDAAAPESLPGQGRELGEGEPPAPAHWPPLSAGARRKNSRRDVQPLPRTPAPGPSEDLELPPHGCEEADRGSSLVGATAQRPARQNLRDLVMGSSPQLKRSVCPGGSSPGSSSGGGRGRGGGDSDSASVASSSAEEESSGGGSVTLDPLEHAWMLSASDGKWDSLEGLLTCEPGLLVKRDFITGFTCLHWAAKHGRQELLAMLVNFANKHQLPVNIDARTSGGYTALHLAAMHGHVEVVKLLVGAYDADVDIRDYSGKKASQYLSRSIAEEIKNLVGALDEGDGESAAGSGGGRWRLSKVLPSHLITYKLSHALEDGGDHHHHHHSAEGWVGGKAKDPGRKASGSSSGRIKPRLNKIRFRTQIVHTTPSFRDPEQPLEGRGEEGVGEERPVKGHSPFTLRPKSNVFG
What are the official names of this protein?
Ankyrin repeat domain-containing protein SOWAHC, Ankyrin repeat domain-containing protein 57, Protein sosondowah homolog C.
What is the protein family that this protein belongs to?
Belongs to the SOWAH family.
Protein: RL34_BACTN
Sequence: MKRTFQPSNRKRKNKHGFRERMASANGRRVLAARRAKGRKKLTVSDEYNGQKW
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: COAD_VESOH
Sequence: MKKIAIYPGSFDPITNGHVDLIKRASKLFDEIIIGISQNSKKKAFLSINDRIDTINTALKDINNIRILSFDTLLVDFASLKNAQVILRGLRAISDFEYEYQLSGINKHLNPNIETLFMTPTEQYANISSSLIKEIIALGGDISVFVPASVKTLLKHRL
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIT_ZIZMA
Sequence: MVPQAKLVVASLILTSALIQTSEAVGGIATYWGQYTETEEGSLAEACASNLYSYINIAYLNIFGEGRYLSLNISGHCSDCTFLGEEIKACQSQGVKIFLSLGGPYGDYHLTTDGDADRVAEQLWSSFLGGSKSTGVYQPLLGDVELDGIDLDIQIGPPEEYDVLARNLKDLTKDRTRPFYLSAAPKCSAYNDSDAYLWTAVETGLFDFVWVKFYNDTSCQYNNDTAAGLDAFYRSWYDWTVSLAEGNKLLIGIPASNETDNSPLGGYIPSDVLNDQIVSVIMTSSKFGGVNVWNRYYDLKTNYSSSIILEYVNSGTKYLPLRTKFMYQNA
What is the function of this protein?
Defense against chitin containing fungal pathogens (Probable).
What are the official names of this protein?
Endochitinase Ziz m 1.0101, Allergen Ziz m 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARAP1_MOUSE
Sequence: MAEGYDAALSVAEWLRALHLEQYTALFEQHGLVWATECQGLSDAGLLDMGMHLPGHRRRILAGLHRAHAPPVPLPRPAPRPVPMKRHIFRSPPVPVTPPEPPPTAGEDEGLPAAPPIPPRRSCLPPACFTPTSTAAPDPVLPPLPAKRHLVEPSVPPVPPRTGPPYPQASLLAKEELLLPSVSPRSQPEPAETPSTLLPAFPQGPLQPPSPPPCPPVIPPKPPRLLPEFDDSDYDDVPEEGPGAPASVMTKEEPLPSRVPRAVRVASLLSEGEELSGDDSEDDDDHAYEGIPNGGWPTSGLNPPLRSLIPDLPLHPMDELPGGPTPITPVIKAGWLDKNPPQGSYIYQKRWVRLDADYLRYFDSNKDAYSKRFVPVACICRVAPIGDQKFEVITNNRTFAFRAESDVERNEWMQALQQAVVEHRARFRLSSASVLGVRGSEQPDRAGSLELRGFKNKLYVAVTGDKVQLYKNLEEFHLGIGITFIDMNVGNVKEVDRRSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTSEVAERIWAAAPNRFCADCGAAQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRKVWTEALIQLFLHLGNGPGNHFWAANVPPSEALEPSSSPGARRYHLEAKYREGKYRRYHPLFGNQEELDKALCAAVTTTDLAETQALLGCGAGVSCFSGDPAAPTPLALAEQAGQTLQMEFLRNNQSTEVPRLDSVKPLEKHYSVTLPTVSHSGFLYKTASAGKPLQDRRAREEFSRRWCVLSDGVLSYYENERAVTPNGEIRASEIVCLAVSPLDTHGFEHTFEVYTEGERLYLFGLENAELAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPCKAGLSLQQAQEGWFALTGSELRAVFPEGPWEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMAWLGVIQKAAASLGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRLLDSLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLAWLEASEIEDEEEKISRYRELLVHLPPVNRATVKALISHLYCVQCFSDTNQMNTHNLAIVFGPTLFQTDGQDYKAGKVVEDLINHYVVVFSVDEEELRKQREEVTAIVKMRVAGTASGTQHAGDFICTVYLEEKKVETEQHVKIPASMTAEELTLEILDRRNVSIREKDYWTCFEVNEKEEAERPLHFAEKVLPIVHGLGIDSHLVVKKYQSMEAMLLYLASRVGDTKHGMMKFREDRSLLGLGLPSGGFHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPVKSLKVYLGVKKKLRPPTCWGFTVVHETEKHEKQQWYLCCDTQMELREWFATFLSVQHDGLVWPSEPSRVSRAVPEVRMGSVSLIPLRGSENEMRRSVAAFTADPLSLLRHV
What is the function of this protein?
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members.  Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding.  Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.  Has a preference for ARF1 and ARF5 (By similarity).
What are the official names of this protein?
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, Centaurin-delta-2, Cnt-d2.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane.
Protein: SYM_METVS
Sequence: MKHLVTTALAYTNGPLHLGHARSTYIPADIFTRYLRLKRENVFHVGGTDNHGVPITLKAEKEGVTPLDIVDRYHNAIKEDLDSLNVSFDSFGRTHSDIHIETAQEFYKTLKENGYIYEKEIEQFYCEKCSMSLADRYVEGKCPFCEGEARGDHCEVCGRHLEPTELLEPYCIHCNSKPEIKKSIHYFFKLSAMKEELTEYITNAKEMPEHVKNMALRWIEELHDWDVSRNLTWGVPIPKSNGQVMYVWIEAPIGYVSFTKELGEIWKDYWISKDVQSKITHFIGKDITVHHAVFWPGILKGVKNYKMPDSVVSGGYLTLENKKMSTSKNWVVWVKDFVEKFSPDYLRYFLMVNAPLNRDTDFSWDDFQKRINTELIDIIGNFSHRTLVFTERKFGKIPNVQKDTLKEEDLLLIRKCEKTTETFDKLIREYNFKDAIMEIILLSKEGNAYFQAMQPWAITDEERLKEVMYTCCTTLKYIVYLLSPFMPVKTGELLDLMNEELDLEIRGNDLKKPKVIFTKLEEMDILKMKEKLNSEIKFEEKVSKNEKTAKKTGAKMELIDIEYFTKVDLRVGKVLEVEDVKKSKKLYKIIVDLGNEQRQIISGLKGDYEVEELIGKNVIVICNLKPAKLCGVESEGMLLAAESDGIVSLLNIDREISLGSKIH
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2388_PECAS
Sequence: MTMTDIALVVLIALALAYAIYDEFIMDKLKGKTRLLVPLKRMNRLDTLIFIGLVGILIYQNVMSNGAIITTYLLISLAFMACYLAYIRRPKLLFKSTGFFYANIFIPYSRIKNMNLSEDGILVIDLEKRRLLIQVTQLDDLEKIYKFMIDNQ
What are the official names of this protein?
UPF0266 membrane protein ECA2388.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NF15_NAEFO
Sequence: TPQIQKPAPQFSKTALLPDE
What are the official names of this protein?
Unknown protein NF015 from 2D-PAGE.
Protein: NBP35_CRYNJ
Sequence: MIATQRPFPIPSPVPLAPSSTVLPTTVPENAPEHCPGVESSQAGKADACEGCPNQSVCAEGPKGPDPDLPLIRERMSSVRRKILVLSGKGGVGKSTFTAGLSWALAADEECQAGIMDIDICGPSIPLLMGLESSTIHTSASGWSPAYALDNLAVMSIGFLLPSSSDAVIWRGPKKNGLIKQFLKDVEWGDLDYMVVDTPPGTSDEHLSIVQYLKEAGIDGAVLVTTPQEVALQDVRKEIDFCKKVGIPILGLVENMSGFVCPNCKNESQIFAPTTGGAEAMGKELGIELLGKVPLDPRIGMTCDQGMSFLDEYPESPATMAYLDIVQRIREILDDE
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NBP35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_XANP2
Sequence: MTAPKSTAPASTAATFRAIPVDDLSPAEAASEHKALAQEITGHDAAYYREDAPVVSDAEYDALRHRYEAIEERFPGLRGEDSLSEKVGAAPSEKFGKVAHKVPMLSLANCFSDEEVVEFVARVKRFLNLGPDDEVAFTCEPKIDGLSCSLHYENGRLTVAATRGDGSQGEDVTQNVRTIADIPERLAGKGVPQTIDVRGEVYMAKADFEALNARQAAAEEKVFANPRNAAAGSLRQLDSSITASRPLKFFAYAWGEASDLPAETQFGVVEAFARWGFTTNPLMVVAKDAAGLIAHYRSIEAQRALLGYDIDGVVYKVNSLELQRRLGFVSRSPRWAIAHKFPAEQATTVLEDIEIQVGRTGALTPVAKLTPVTVGGVVVSSATLHNEDEIARKDVRIGDTVVVQRAGDVIPQVVRVIEEKRPAGSKPYEFPTHCPACGSHAVREVDTKSGKVDAVRRCTGGLICPAQMVERLRHFVSRNAFDIEGLGEKQVRAFYEWGLIASPADIFTLETRNARSLQRLENRDGWGKTSAANLFAAIAERRTVAVDRFVFALGIRHVGETNAKRLMRHYGTVEALEAGALAAVIPGEEHPKGNEAWQEMIGIDGIGDVVAEAVIEFFGEPRNREVVTALLKEVTPEPMEQVAAASPVSGKTVVFTGSLEKMTRDEAKAMAERLGAKVAGSVSAKTNLVVAGPGAGSKLEKAQALGVQVITEDEWFELVG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ACPS_ECOLU
Sequence: MAILGLGTDIVEIARIESVIARSGERLARRVLSDNEWAIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVVNMHVTLADERHYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF3_CHICK
Sequence: MLVIWLLLLALLPEPRVPAATASPRAPRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQIHPGGKINGTLEKNSVFSILEITAVDVGIVAIKGLFSGRYLAMNKRGRLYASENYNTECEFVERIHELGYNTYASRLYRTVPSGASTKRKASAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDSKDHEMVRLFHTNVRYRESLLKPPSKNQRRRRGR
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.
What are the official names of this protein?
Fibroblast growth factor 3, FGF-3, Heparin-binding growth factor 3, HBGF-3.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_PSEAE
Sequence: MEKREELYRGKAKSVYQTDDADRLILLFRNDTSAFDGKRIEQLDRKGAVNNKFNAFIMQKLEAAGIPTQFDKLLSDTECLVKKLDMIPVECVVRNFAAGSLVRRLGVEEGIALTPPTFELFLKNDALGDPFINESHVQAFGWATPEQLAQMKTYSFKVNEVLNKLFDDAGLLLVDFKLEFGLFHGQIVLGDEFSPDGCRLWDKETRKKMDKDRFRQGLGDVIEAYEEVAKRLGVPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MINC_AGARV
Sequence: MILEVLMSQSVTIKSNKYGINLILDADMPFADLIKAVVEKFKASANFFKNAKLAISFEGRHLSDEEQQQIIAAIEENTTIEILCIVESGTEQEAIMKEQVEAFNEAVQKQCENVATVSVPEQFYRGTLRSGQVITSESSVTIIGDVNPGAKIIAQGNIVILGALKGNVHAGCTGDRSCFVFALDMQPIQIQIGDLIAKSPDEPQPKHRVRRKEKPAQEQAQIAIAKDGYIYIEPITKNILNSI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.