PharMolix/UniProtQA huggingface dataset:
Protein: MDTD_YERPN
Sequence: MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGGAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGSYWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSP70_TRIRU
Sequence: MAPAVGIDLGTTYSCVGIFRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQVAMNPINTVFDAKRLIGRKFNDAEVQADMKHFPFKVVEKSGKPIVQVEFKGEEKQFTPEEISSMVLTKMRETAEAYLGGTVNNAVITVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAGGIAYGLDKKADGERNVLIFDFGGGTFDVSLLTIEEGIFEVKSTAGDTQLGGEEFDNRLVNHFVNEFKRKNKKDLSTNARALRRLRTACERAKRTLSSAAQTSIEIDSLYEGVDFYTSITRARFEELCQDLFRSTMEPVERVLRDAKIDKSSVHEIVLVGGSTRIPKIQKMVSDFFNGKEPNKSINPDEGVAYGAAVQAAILSGDTSSKSTNEILLLDVAPLSLGIETAGGVMTPLIKRNTTIPTKKSETFSTFSDNQPGVLIQVFEGERARTKDNNLLGKFELTGIPPAPRGVPQIEVTFDVDANGIMNVSALEKGTGKTNKIVITNDKGRLSKEEIERMLAEAEKYKAEDEAETARIGAKNGLESYAYSLKNTLSDSKVDEKLDAADKEKLKSEIDKVVAWLDDNQTATKEEYESQQKELEGVANPIMMKFYGAGGEGGAPGGFPGAGAGGPGGFPGAGAGGAAAHDDGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PXPA1_PSEAE
Sequence: MTEVDLNSDMGEGFGPWTIGDGVDAAIMPLISSANIATGFHAGDPSSMRRTVEMAAEHGVAIGAHPGFRDLVGFGRRHIAAPAIELVNDMLYQLGALREFARLQGLSLQHVKPHGALYMHLARDEVAARLFVETLQRLEPELLLYCMPGSATWRIGRELGQPLVREFYADRDYDRSGSIVFTRRVAALDPQQVADKVLRACREGKVRTVEGEDLDIAFDSVCIHSDTPGALELVASTRARLEGAGIRIKAPR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A 1, 5-OPase subunit A 1, 5-oxoprolinase (ATP-hydrolyzing) subunit A 1.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y298_ARCFU
Sequence: MDELELRIRKAEKLVQDAKKEFEMGLYERCCSTAYYAMFHAAKAMLLGYGRDSKTHRGTIYLIWECREELGLSDDDCSKLSRAFDLREESDYGIYKEVSKDLAIKILKDAEIFVQKAKNAVNKNR
What are the official names of this protein?
UPF0332 protein AF_0298.
What is the protein family that this protein belongs to?
Belongs to the UPF0332 family.
Protein: HIS2_PROMA
Sequence: MMPMNQEFIQKLRFNEKGLIPAIAQDWLDGAILMMAWMNKESLEKTLITGEVHYWSRSREKLWHKGETSGHFQILKGIRFDCDSDVMLLSIEQVGSIACHTGARSCFFQEVEENIPDLEQNSTFNRPLSNTCSELFEVIKDRSSNPQKNSYTNSLLKDGDNKILKKIGEEGSEFVMACKDNDHESISNEAADLIFHIQVALKYHKVEWRDVLEVLAKRRQSKSNPK
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_PHEZH
Sequence: MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRNRHGAAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGGNGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIADVGLVGLPNAGKSTFLAAASAAKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVLIHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAAGMDVRLVSGFTGENVTELLREAFALVRERKRAAAEEAAGPSEGWTP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_METS5
Sequence: MDVQKELEKVIELTRSQNRWRRTETINLIASENVMSPLAEALYMSDFMSRYAEGKPFKRFYQGTKYVDEVETLAMDYMNQVTGSKFCDLRPTSGTLANAAVFRVLANPGDKALIAPVQAGAHVSHTKFGTLGALGIEHIEMPYDEENMNVDVDRAVKMIEQIKPKFVVLGGSLYLFPHPTKDLAPHVHSVGAKLVYDAAHVYGLMTGKVWSNPLDEGADFLNVSTHKTFPGPQGGAIFSNEEEEFKKVSRTIFPWFVSNHHLHRLPSTAVTALEMKVYGEDYAKQITRNSKALAEALASFGFKVIGEHLGYTKSHQVAVDVKNLGGGAYVAKTLESANIIVNKNLLPHDPPEAVNDPSGIRIGVQEMTRFGMKEGEMEEIAELMKQILVDKRDINEMRRKVTEMRSRFLEVKYALTYDLSKYNSKLIPMIL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_GEOMG
Sequence: MLTIVAIALFGALGCLARYLLAGWVYAFVGRGFPYGTLTVNVVGAFLIGLIMEFSLRTTLIPQELRIGLTIGFLGGLTTFSTFSYETFRLLEDGEFITAAVNVLASVLVCLACTWLGIMTARHL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PETG_PROMS
Sequence: MIEPLLCGIVLGLVPITLLGLFVSAWNQYRRGSGMLDID
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PSIE_YERPY
Sequence: MAKNSRSQWIAKNLQRLLNVGLIMLAAILVVFLVKETIHLGKVLFLSNQETSSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILVLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y847_LACCB
Sequence: MSTLDQTVHFDFRDNNPKNVHETLETVYKALEEKGYNPINQIVGYLISGDPAYIPRYNDARNLIRKHERDEIIEELVRNYLGKEQA
What are the official names of this protein?
UPF0297 protein LCABL_08470.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: CETN2_MOUSE
Sequence: MASNFKKTTMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY
What is the function of this protein?
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
What are the official names of this protein?
Centrin-2, Caltractin isoform 1.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Nucleus envelope. Nucleus, nuclear pore complex.
Protein: KCNJ6_MESAU
Sequence: MTMAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDILTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHVEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELANRAELPLSWSVSSKLNQHAELETEEEEKNPEEQTERNGDVANLENESKV
What is the function of this protein?
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 2, GIRK-2, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYCN_MOUSE
Sequence: MSLLCPLLLALALVAVPGAHGNCPVPADLKKSDGTRTCARLYEKSDPYYDNCCQGPVLSVEPGTDLPYLPSGWSNTASSLVVGQRCEITVWSLPGKHGKTRKFTAGSYPRLEEYRKGIFGDWSDSISALYCKCY
What is the function of this protein?
Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other.  May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.
What are the official names of this protein?
Syncollin.
What are the subcellular locations of this protein?
Zymogen granule membrane; Peripheral membrane protein; Lumenal side. Zymogen granule lumen. Note=Associated in a cholesterol- dependent manner with lipid rafts of zymogen granule membranes.
Protein: GRRE1_HUMAN
Sequence: MYCCSAQDSKMDYKRRFLLGGSKQKVQQHQQYPMPELGRALSAPLASTATTAPLGSLTAAGSCHHAMPHTTPIADIQQGISKYLDALNVFCRASTFLTDLFSTVFRNSHYSKAATQLKDVQEHVMEAASRLTSAIKPEIAKMLMELSAGAANFTDQKEFSLQDIEVLGRCFLTVVQVHFQFLTHALQKVQPVAHSCFAEVIVPEKKNSGSGGGLSGMGHTPEVEEAVRSWRGAAEATSRLRERGCDGCLAGIEVQQLFCSQSAAIPEHQLKELNIKIDSALQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSEAEAQQTGRRQTPPQPMQCELPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMLQLMKEAGCYNGITSRDDFPVTEVLNQVCPSTWRGACKTAVQLLFGQAGLVVVDTAQIENKEAYAPQISLEGSRIVVQVPSTWCLKEDPATMSLLQRSLDPEKTLGLVDVLYTAVLDLNRWRAGREQALPCIQIQLQREICDFGNQADLPSGNGNKSSGGLQKTFSKLTSRFTKKASCTSSSSSTNYSIQNTPSKNIFIAGCSEEKAKMPGNIDTRLQSILNIGNFPRTTDPSQSAQNSSNTVANGFLMERRENFLHGDDGKDEKGMNLPTDQEMQEVIDFLSGFNMGQSHQGSPLVTRHNSAATAMVTEQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLLQPIGPQQPPPQPRAPGKWVHGSSQQPAQAVGAGLSPLGQWPGISDLSSDLYSLGLVSSYMDNVMSEVLGQKPQGPRNNTWPNRDQSDGVFGMLGEILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHGRRPGNPRGNWPPMDDAHRTWPFPEFFTEGDGLHGGWSGAQGDSASSSDETSSANGDSLFSMFSGPDLVAAVKQRRKHSSGEQDTSTLPSPPLLTTVEDVNQDNKTKTWPPKAPWQHPSPLPSTLPSPSAPLYAVTSPGSQWNDTMQMLQSPVWAATNDCSAAAFSYVQTPPQPPPPPAHKAAPKGFKAFPGKGERRPAYLPQY
What is the function of this protein?
Acts as an effector of RAC1 (PubMed:31871319).  Associates with CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation (PubMed:29395067).  May also play a role in miRNA silencing machinery (PubMed:29395067).
What are the official names of this protein?
Granule associated Rac and RHOG effector protein 1, GARRE1.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: RL23_RALPJ
Sequence: MTQVAKNDHRLMQVLLAPVVSEKATLVAEKNEQVVFEVARDANKGEVKAAVELLFKVEVESVQILNQKGKQKRFGRFMGRRDHVKKAYVSLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: COAD_RENSM
Sequence: MRRAVCPGSLDPIHNGHLEVIARAAGLFDEVIVAVSTNYAKKYRFSLEERLEMASETLASLRGIVIEPMGAGLLAEYCRQRGASAIVKGIRSSSDFDYEVPMATMNRQLTGVETVFLPAEARYLHLSSTMIKEVEGLGGDVSDYVPRAVLRRFHEGKETN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SACD2
Sequence: MRHRHSGRQLNRNSSHRKAMFKNMVTSLVEHELIKTTLPKAKELRRYAEPLITLSKSDSVANRRLAFARLGNKATVGKLFNELGPRYEGRPGGYLRIMKCGFRAGDKAPMAYVELVDRPAPVAAEPVESSED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: IL2_AILME
Sequence: MYKMQLLYCIALTLVLVANSAPTPSSPTKETQQQLEQLMLDLRLLLNGVNNYENPKLSRMLTFKFYMPKKATELKHLQCLAEELKLLEEVLYLDQSKNLHLTDIKELMSNINVTLLKLKGSEASFKCEYDDETVTITEFLNKWITFCQSIFSTLT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CWP19_ARATH
Sequence: ADREPNHFVA
What are the official names of this protein?
17 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: UPPP_ERYLH
Sequence: MTFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFFKDVLTLARGGFASIGIGTDRPDAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWFNITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEVKKFEDMSWRDGLIVGIAQALAIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDALIAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3NO23_BUNCA
Sequence: MKTLLLTLVVVTIVCLDLGYTLTCLICPEKDCQKVHTCRNEEKICVKRFYDKNQLGWRAQRGCAVSCPKAKPNETVQCCSTDDCNR
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak toxin 3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_BOVIN
Sequence: MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial, ATP synthase F1 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PRP_CALVI
Sequence: FVDRNRIPRSNNGPKIPIISNP
What is the function of this protein?
Antibacterial peptide active against Gram-positive bacterium M. luteus and Gram-negative bacterium E. coli.
What are the official names of this protein?
Proline-rich peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_PSEA6
Sequence: MSTTLYDKIFQAHIVDEIGDDALLYIDRHLIHEVTSPQAFDGLAQKGRKVRRPDLTFATMDHSISTRSLAIDACGPANKLQLQTLADNCEANGIQLFPVGHQKQGIVHVMGPELGLIKPGMTVVCGDSHTATHGAFGALAFGIGTSQVEHVFATQTLKQSKGKCMQVKVNGARPLGVTAKDIILAIIGKIGHAGATGCVIEYCGDTIEGLSMEERMTVCNMSIEAGAKAGLIAPDQTTFDYLAGREYAPKGADWDAAVAYWKTLKSDTDAKFDIVVELAATDIAPQVTWGTNPGQVIGVNQPIPAPEDFSDPIDRDSAVKALKYMDIQAGQKLADLTVNHVFIGSCTNGRIEDMRAAAAIAKQGKVAENVTAIVVPGSVAVKAQAEAEQLDKIFLDAGFEWRLPGCSMCLGMNDDILSQGDRCASTSNRNFEGRQGRGARTHLVSPAMAAAAALAGRFADTRDFIAND
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TRMA_ACTP7
Sequence: MNLPIERYADLLAEKAKNLTALLVPFNPPELEVFESETSHFRMRAEFRVWHDTNEVGENELYHIMFDQETKQRYRVEQFPIANHLINKMMSSLLAEIKGNELLTRKLFQVDYLSTLSGEIAVSMLYHKKLNEEWQAEAAALKARLEHQGFKVQIIGRATKQKIALDRDYVEEVLPVDGRNLIYRQVENSFTQPNAKMNIKMLEWARSCTRHSSGDLLELYCGNGNFSIALAENFRQVLATEISKSSVQSAQYNIEQNGIDNLQIIRMSAEEFTQAMNGVREFNRLKGIDLKAYDCNTIFVDPPRAGLDQDTLNMVQAYERILYISCNPYTLAENLRQLSLTHRIERAALFDQFPYTHHVESGVWLIRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: LEUD_DEIDV
Sequence: MPRVHVFARDHINTDEIIPARHLTTDIEAELAPYAMEDYDRDFAKRVQPGDIIVAGADFGCGSSREHAVWALRGAGVGAVIAPNFARIYYRNSINNGFLALECDGIVEAFQDGDEANLDLKGGTITNLRTGQTLTFVPVPQFALDVQKAGGWLEYMRAQVPAEADDSSSAQPHPGKENAHA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: ATP6_ECO7I
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CARM1_ANOGA
Sequence: MARMQGCSVLVLDDSDKLVNKYDHKVTVVCSYDPQGMAVRLLQEGATPPKQLEEYLVSGAGTTHLSRGHTSHMLVVGGELVLFRFASRGDCQQFRSLLHKLSGKVNSVFNLRTEDSSASQYFQFYGYLSQQQNMMQDFVRTSTYQRAIYNNAQDFQNKIVLDVGAGSGILSFFAVQAGAAKVYAVEASNMAQYAQQLVSSNNLTDRIIVIAGKIEEIDLPERVDVIISEPMGYMLYNERMLETYLHGKKWLKPDGKMYPSRGDLHVAPFTDEALYMEQYNKANFWMQTEFHGVNLVALRDAAMKEYFRQPIVDTFDIRICMAKSIRHTTNFLTADEKDLHRIQIDVEFHMLETGTCHGLAFWFDVEFAGTCSQIWLSTSPTEPLTHWYQVRCLLQTPIFVKQGQVLSGKVVLAANQRQSYDVEIDLKLEGTMISSSNTLDLKNPYFRYTGAPVAAPPGSNTTSPSEAFWSQLDAQGARNAVNLVNGITVNGLGEVDMSSTIINTNLMAIGGGANGGGPGGHQPNIHPGLISSTGRQQQQQQQQQQQQAAVGPQQQQQQQSTTAQQLAMTPPIGCAATSTQNVAQHQLIGGAISPSLFTSPAQPILNSHHHHPGQPIHGNQFY
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling.
What are the official names of this protein?
Histone-arginine methyltransferase CARMER, Coactivator-associated arginine methyltransferase 1, AgCARM1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.