PharMolix/UniProtQA huggingface dataset:
Protein: RRF_PARXL
Sequence: MSVADIRKGAEQKMQRSIDAFKNDLSKIRTGRAHTGLLDHIQCDYYGSPVPISQVANLTLIDARTIGVQPWEKKMVPVVEKAIRESDLGLNPATQGDVIRVPMPALTEERRRELTKVVKSEAETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRAGDDVQKLTDRFVAEIDKLVVTKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_FALSP
Sequence: MAPNIRKSHPLMKMINNSLIDLPTPPNISMWWNFGSLLGVCLATQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASLFFICIYMHIGRGIYYGSYLYKETWNTGIILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGLTLIHLTFLHESGSNNPLGVTSNCDKIPFHPYYSLKDLLGFMLMLLPLMALALFTPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLSPLLHKSKQRTMTFRPLSQSLFWLLVTNLLILTWVGSQPVEHPFIIIGQLASLSYFTILLILFPLAGALENKILNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS6_SYNE7
Sequence: MKDFYYETMYILRADLTEEQVEQAIAKYQTLLTEAGAEVQDTQHRGKRRLAYLINKQREGIYVQINYTGDGSQIAPLERALRLSEEVLRFLTVKQEVRPPAPVAVEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: VATD_THESM
Sequence: MTRILKVKPTRMELLRLKRRIKLAEKGHKILKEKQDALIMEFFTIYDEALALRREVNQKIAEAFEQLRLAEIDVGIVKLSEIALSVKSNKEIKIKRRNIMGVPVPLIEAEGFRRDPYERGYAFVSTSPKVDVTAETFEEVLELVTRLAEIEETLKRLAKEIEKTKRRVNALEYIIIPRMAETVKYISQHLDEMERENFFRLKRVKALLEAKAQG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: ATPB_ELAOL
Sequence: MRTNPTTSSPVVPTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRVLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: LIVB7_BRUME
Sequence: MEKHLIALSVAALLAGAAPASADIKMGSLYPFSGPLALLGDESARGLEIAVEEINAKGGVQGEKIVLVRGDAVDNNQAIGEARRLISVENVAGIFGSFSSGRAVAASQVSELAGLPYFELGAVADEITDRGLENVYRANPYARDFAQMIVEMLQKKIAPKLGRDSKDLKIAVIYEDSSYGTSVAKHEETFLKEAGLNMVLSQSYPGNTVDMSSLVLDLKSAGADVVLQTSYQSDSVLFLQQANEGGYKPSAIVGAGGGYSLQPTADAVGHDVIEAAYDVDFTQFAVNTSFTPGLEEFVEAYKKKYGETPRSGHSLTNYVGAKVILEALNKVKGFDAAAVKQALSAVDIEAGKNAMGYGFKFDQNNQNERASMMGMQWQDGKLVTVYPDAAAISEIRLPQ
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 7.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: EX7L_SHEAM
Sequence: MQVPKNDVYTVSRLNGEVRQLLEGQLGRIWLTGEISNFSSPSSGHWYLTLKDSHSQLRCAMFKGRNTTVAFKPINGQQVLVRGSISVYEPRGDYQLLIEAMFPAGDGLLAAQFEALKMKLAAEGLFAQDTKRPLPESIQRIGVITSPTGAAIRDVLHVLKRRDPSVEVVIYPTAVQGTGADKDIIRAIELANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHAIYNSTLTIVSAVGHEVDTSIADFVADVRAPTPSAGAELLSGDQSHKQQKLAGALARLTQGWRHYALKRHSGLISLQSRLDRQDPKRQLQQQSQRLDELELRLTSSIQRRLSSHTLTTERLKARLERHSPAQRLMMEQQRLTYLDERLKGAMEDRLEDAQTHLGGLSHSLASVSPLATLSRGYSITRDAGGRVLTQASSMKTGDTIETQLEQGSLLARVIEIKPE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL3B2_MOUSE
Sequence: MSAAETGSEPSQGAGPSEATLHSLREAFNAGRTRPTEFRTAQLRSLGRFLQENKELLQDALAKDVGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVSTNLLTKLSSAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQYLDQSCFAVMLGGPEETRQLLEHKFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNSITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCGRVAIGGQSDEGERYIAPTVLVDVQETEPVMQEEIFGPILPLVTVRSLDEAIEFINRREKPLALYAFSNNNQVVNQMLERTSSGGFGGNDGFLYLTLPALPLGGVGNSGMGRYHGKFSFDTFSHHRACLLRSPGMEKLNDLRYPPYGPWNQQLISWAIGSRSCTLL
What is the function of this protein?
Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
What are the official names of this protein?
Aldehyde dehydrogenase family 3 member B2, Aldehyde dehydrogenase 8.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: GLMU_LISMH
Sequence: MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQEEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASKLMQRRINENHMRNGVTLVNPESTYIDIDVKIGQDTVIEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDNVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPDDALGIARAKQDNKLGYAKHLNHGK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFTF_MYCS2
Sequence: MTGPRLPDGFAVQVDRRVKVLGEGAALLGGSPTRLLRLAPTAQNMLSGGRLEVHDAVSAQLARTLLDATVAHPRPASGPSHLDVTVVVPVRDNASGLHRLMAALRGLRVIVVDDGSAIPVQPSDFSGMHCDVQVLRHTRSNGPAAARNTGLASCETDFVAFLDSDVVPKRGWLEALLGHFCDPAVALVAPRIVGLHNADNIVARYESVRSSLDLGVREAPVVPHGTVSYVPSAAIICRRSALVEVGGFDETMHSGEDVDLCWRLVESGARLRYEPIALVAHDHRTNLRAWFHRKAFYGTSAAPLTVRHPGKTSPLVISGWTLMVWLMLGVGSFFGYLASLAAAVFAGTRIARALSVVETEPKEVAVVAAHGLWSSALQLCSAICRHYWPIAMIAAVLFRRARHAVLVAAVVDGVVDWVTRRGNADDDTKPVGLLTHIVLKRLDDIAYGTGLWTGVVRERHLGALKPQVRS
What is the function of this protein?
Involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT).  Acts as a glycosyltransferase that catalyzes the oligoglycosylation of pre-mycofactocin (PMFT), adding up to nine beta-1,4-linked glucose residues (PubMed:33014324).  Is required for the in vivo ethanol assimilation in M. smegmatis (PubMed:31113891).
What are the official names of this protein?
Pre-mycofactocin glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YABA_LISMH
Sequence: MDKKAIFDSVSNMEEQIGELYQQLGDLKTNLGEMLEENNRLNLENEHLRRRLSLTDEATPEPKAETEAEHGVMAPNRKEAMQQMIELGEGYDNLVQLYKEGFHVCNVHFGSPRGNDEDCLFCLSLLNKK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: NOVV_STRNV
Sequence: MRGILLAGGTGSRLWPVTRAISKQLIPVFDKPMIYYPLTTLMMAGVREILVITRPDDQRQFRHLLGDGSQLGLRLEYAVQERPEGIAQAFVLGAEFIGDQSVALVLGDNIFHGAGLGTRLRQYNDPAGARIFAYVVADPKAYGVVEFDEAGRAVSIEEKPARPKSRYAVPGLYFYDNRVLDVVHGLVPSRRGELEITAVNETYLKWGQLRVTTLDRGTAWLDTGTFASLVQASEYVRVVEERQGLKIGCVEEVAWRCGFIGNDQLRDLSRPLLKSGYGRYLLDLLADHEELKEVKPS
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate in the novobiocin biosynthesis pathway, an aminocoumarin family antibiotic that targets bacterial DNA gyrases.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, Novobiocin biosynthesis protein V, dTDP-glucose pyrophosphorylase, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.
Protein: Y1320_SALTO
Sequence: MPGMSRHNQSVGAYGERCALRHLITAGLRPVARNWRCPHGEIDIIAWDGPVLAICEVKTRRTDTFGTPTAAVTGTKARRLRLLAARWLAETGTRADEVRFDVLSIRLTGGPPHVEHLKGAF
What are the official names of this protein?
UPF0102 protein Strop_1320.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NUON3_STRGG
Sequence: MSATAVHSLWTTASGVTSAAPGNSFTAPKIEYTQLMPVLIIVVAAVLGILVEAFVPRRARYHTQLFLTVVAVAGSFAAIVGLAAGGYGTTDAGIVAMGAIAIDGPTLFLQGTILLVAMVALFTFAERRLDPGSNGNRVDSFAAQAGSVPGGEGEKAAVRAGFTTTEVFPLLLFSVAGLLVFPAANDLLTLFIALEVFSLPLYLLCAVARRKRLMSQEAAVKYFLLGAFSSAFLLFGIALLYGYAGSLSYADIANVVDGSVLEIDPALADTMGNDALLLIGGAMILTGLLFKVGAVPFHMWTPDVYQGAPTPVTGFMAAATKVAAFGALLRLLYVALPGLAWDLRPVMWAVAIVTMLGGAIVAITQTDIKRLLAYSSIAHAGFILAGVIAASPEGISSVLFYLLAYSFVTVGAFAVVTLVRDAGGEATHLSKWAGLGRRSPLVAAVFAVFLLAFAGIPLTSGFSGKFAVFKAAAEGGAGALVVVGVLSSAVAAFFYIRVIVLMFFSEPKADGPTVAVPSPLTMTTIAVGVAVTLVLGLAPQYFLDLASQAGVFVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 3, NADH dehydrogenase I subunit N 3, NDH-1 subunit N 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_SULDN
Sequence: MAITKQDVLEFISGLSVLELSELVKEFEEKFGVSAQPVAVAGGAVAAVAVEEQTEFNVIITDAGDKKINVIKVVRALTGLGLKEAKDATENVPSTIKEGVDKETAMNAKKELEEAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FAEE_ECOLX
Sequence: MSKRNAVTTFFTNRVTKALGMTLALMMTCQSAMASLAVDQTRYIFRGDKDALTITVTNNDKERTFGGQAWVDNIVEKDTRPTFVVTPSFFKVKPNGQQTLRIIMASDHLPKDKESVYWLNLQDIPPALEGSGIAVALRTKLKLFYRPKALLEGRKGAEEGISLQSRPDGRTMLVNTTPYIFAIGSLLDGNGKKIATDNGTTQKLLMFMPGDEVQVKGNVVKVDSLNDYGELQTWTINKKKPAAPEAAKAEKADTAEQK
What is the function of this protein?
Mediates assembly of pili by forming soluble multimeric complexes with pili subunits as an intermediate step in the assembly process.  This protein is involved in K88 pili assembly.  Protects pilin protein from proteolytic degradation by DegP and from premature polymerization.
What are the official names of this protein?
Chaperone protein FaeE.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RPOZ_STRP8
Sequence: MLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MEPA_STAAN
Sequence: MKDEQLYYFEKSPVFKAMMHFSLPMMIGTLLSVIYGILNIYFIGFLEDSHMISAISLTLPVFAILMGLGNLFGVGAGTYISRLLGAKDYSKSKFVSSFSIYGGIALGLIVILVTLPFSDQIAAILGARGETLALTSNYLKVMFLSAPFVILFFILEQFARAIGAPMISMIGMLASVGLNIILDPILIFGFDLNVVGAALGTAISNVAAALFFIIYFMKNSDVVSVNIKLAKPNKEMLSEIFKIGIPAFLMSILMGFTGLVLNLFLAHYGNFAIASYGISFRLVQFPELIIMGLCEGVVPLIAYNFMANKGRMKDVIKAVIMSIGVIFVVCMIAVFTIGHHMVGLFTTDQAIVEMATFILKVTMASLLLNGIGFLFTGMLQATGQGRGATIMAILQGAIIIPVLFIMNALFGLTGVIWSLLIAESLCALAAMLIVYLLRDRLTVDTSELIEG
What is the function of this protein?
Multidrug resistance efflux protein (By similarity).  Contributes to resistance to the glycylcycline antibiotic tigecycline.
What are the official names of this protein?
Multidrug export protein MepA.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STP1_SHEEP
Sequence: MSTSRKLKSQGTRRGKNRTPHKGVKRGCSKRKYRKSSLKSRKRCDDANRNFRSHL
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Spermatid nuclear transition protein 1, Protein T, STP-1, TP-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Protein: PYRB_SERP5
Sequence: MANPLYHKHIISINDLSREDLELVLRTAASLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFADGSNTSLGKKGETLADTISVIGTYVDAIVMRHPQEGAARLATEFSGGIPVLNAGDGANQHPTQTLLDLFTIQETQGRLNNINIAMVGDLKYGRTVHSLAQALAKFEGNRFFFIAPDALAMPAYILQMLEEKGIQYSLHSSIEEVVPELDILYMTRVQKERLDPSEYANVKAQFVLRAADLAGARDNLKVLHPLPRIDEITTDVDKTPYAYYFQQAGNGIFARQALLALVLNADLAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RPOA_ACIBS
Sequence: MTRTANEFLTPQAIKVEAVSGTSAKVILEPLERGFGHTLGNALRRILLSSLPGAAVVEVEIEGVEHEYSTLEGLQQDIVELLLNLKGLSIKLFDQNEAYLTLEKQGPGDITAADLRLPHNVEVVNPEHLIGTLSATGSLKMRLKVSQGRGYETSDSRFPEGETRPVGRLQLDASYSPIKRVSYTVENARVEQRTDLDKLVIDLETNGTVDPEEAIRKAATILQQQIAIFVDLQKDQTPVAQEPREEVDPILLRPVDDLELTVRSANCLKAENIYYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASKGLQLGMRLENWPPASLRMDDRFAYRSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RPOB_CALS4
Sequence: MVRPVQAGSRTRMSFAKIDEVLEIPDLIEVQKKSYQWFLEEGLKEVFQEISPIESFTGNLALEFVDYRLENNPKYSVEECKDRDTTYAAPLKVKVRLTNRETGEIKESEVFMGDLPLMTDKGTFIINGAERVIVSQLVRSPGVYYDQQFDKFGKKLIFATVIPNRGAWLEYEEDSNDVIYVRIDRTRKVPITVLLRAIGYNTDIQILDLLGEEEKLKATLDKDTTKSEEEALIEIYKRLRPGEPPTVESARSLFNALFFDPKRYDLAKVGRYKFNKKLALKARIANHKSAKRIVNPITGEVLVEEGEKITREKAEEIQNCGINEVEILVDGKVVKVVGNNTVDINKYPMPYDVSSLNIKELVNVRVLREILDNFSDEEAVLNEIKNRMDELVPKHITKDDIVATISYQLNLTHGVGFVDDIDHLGNRRVRSVGELLQNQFRIGLARLERVVKERMTIQDVNEVTPQNLINIRPVVAAIREFFGSSQLSQFMDQTNPLSELTHKRRVSALGPGGLSRERAGFEVRDVHYSHYGRICPIETPEGPNIGLITSLTTYARVNEYGFIETPYRKVDKATGTVTDEIVYMTADEEDEYIIAQANEPLDENNRFINDRVVCRLREEIISVPPTEVDFMDVSPKQIVSVSASLIPFLENDDANRALMGSNMQRQAVPLLKPEAPIVGTGMEYKAAVDSGAVILAKNDGIVEKVTADKVVIRTKDGKRDEYHLLKFKRSNQGTCINQRPIVNEGDEVKKGQVICDGPSTDHGELALGKNVLVGFMPWEGYNYEDAILISEELVMDDSLTSIHIEEYDAEARDTKLGPEEITREIPNVGEDALKDLDERGIIRIGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGESGIVVDVKVYSRENGDELPPGVNQMVRVFVAQKRKISVGDKMAGRHGNKGVISRILPVEDMPFLPDGTPLQICLNPLGVPSRMNIGQVLETHLGLVAKALGWYIASPVFDGATEKDIEELLAKSGFSPDGKVQLYDGRTGEPFDNKVTVGYMYMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTVKSDDVTGRVKAYEAIVKGENIPEPGIPESFKVLVKELQSLALDVKVITEDGQEIPIKEFEDDDDDVPDATLNINIEGREDAPPEEVYEEEYEEEPEELPEDIDFEPDNFDIDSEDLFMDDDYDG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ZFP37_HUMAN
Sequence: MSVSSGVQILTKPETVDRRRSAETTKEAGRPLEMAVSEPEASAAEWKQLDPAQSNLYNDVMLENYCNQASMGCQAPKPDMISKLEKGEAPWLGKGKRPSQGCPSKIARPKQKETDGKVQKDDDQLENIQKSQNKLLREVAVKKKTQAKKNGSDCGSLGKKNNLHKKHVPSKKRLLKFESCGKILKQNLDLPDHSRNCVKRKSDAAKEHKKSFNHSLSDTRKGKKQTGKKHEKLSSHSSSDKCNKTGKKHDKLCCHSSSHIKQDKIQTGEKHEKSPSLSSSTKHEKPQACVKPYECNQCGKVLSHKQGLIDHQRVHTGEKPYECNECGIAFSQKSHLVVHQRTHTGEKPYECIQCGKAHGHKHALTDHLRIHTGEKPYECAECGKTFRHSSNLIQHVRSHTGEKPYECKECGKSFRYNSSLTEHVRTHTGEIPYECNECGKAFKYSSSLTKHMRIHTGEKPFECNECGKAFSKKSHLIIHQRTHTKEKPYKCNECGKAFGHSSSLTYHMRTHTGESPFECNQCGKGFKQIEGLTQHQRVHTGEKPYECNECGKAFSQKSHLIVHQRTHTGEKPYECNECEKAFNAKSQLVIHQRSHTGEKPYECNECGKTFKQNASLTKHVKTHSEDKSHE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 37 homolog, Zfp-37.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_SHIFL
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPT1_CAEEL
Sequence: MRYFPLLLCLLAITTAEFRNATKQVPVVMWHGMGDCCCNPLSMGSVKKLFEEQIPGVYVHSLQLGSSITKDIEHGFYANTNELVYMACIKIKNDPELKNGYNAIGFSQGAQFLRAVAQRCPNPPMKNLVSVGGQHQGVFGAPYCIGDNIMCNGVRRLIDLGAYLPFVQKRVVQAQYWHDPNQVEEYKKRSIFLADINNENNNNPTYKRNLLSLKNLVLVKFNQDHMVVPKDSSWFGFYKDGDIDTILPMNETDLYKEDRIGLKKLHESGRIHFMDVDGDHLQIPRSVLVNDIIKKYFM
What is the function of this protein?
Removes thioester-linked fatty acyl groups such as palmitate (hexadecanoate) from modified cysteine residues in proteins or peptides.
What are the official names of this protein?
Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the palmitoyl-protein thioesterase family.
Protein: MTOX_ECOHS
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: RS7_PELTS
Sequence: MPRRGAVPKREVLPDPVYQSKVLTKLINQVMLKGKKSLAESIVYGAMDIIKEKTGKNPLEVFETAMKNVMPVLEVKARRVGGANYQVPVEVRHDRRQTLAIRWLTNYARERAGKSMKEKLANEIMDAAAGTGGAVKKKEDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: H2B3_MAIZE
Sequence: MAPKADKKPAAKKPAEEEPATEKAEKAPAGKKPKAEKRLPAGKSAGKEGGEGKKGKKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAAESAKLARYNKKPTVTSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RIMM_XANCB
Sequence: MKPTERRILLGRIVGAFGVKGELKLESWTEPRSAIFRYQPWIVRTPSGQESVLSGVRGRDQGKNLIAVFPDITDRDTVEAMHGTEIYVARSALPPPKPDEYYWVDLEGLQVETVEGIKLGAVSHLFSTGSNDVVVVRGDRERMIPFVLPEYVKSVDFEANLIVVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.