PharMolix/UniProtQA huggingface dataset:
Protein: FGF2_SHEEP
Sequence: MAAGSITTLPALPEDGGSSAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: LIS1_MAGO7
Sequence: MTSILTPRQAEELHKAIIAYLSANNLSSSATALRTELGLAEDVFDAATAKKYEGLIEKKWTSVVRLQKKIMDLESRNNALQSELDNATPLSLAKRNTDPTAWLPAPRPRYSLESHQNTINCIAFHPVYSSIASGSDDCTIKIWDWELGELERTIKSHTRPVLDVDFGGPRGGILLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSAIRFMPSGASGAAMSGNLLVSASRDMTLKIWDVSTGFCLKTIRGHTAWIRDVYPSLDGRYLLSTGDDSTVRLWDLSVTNPENRLTMIGHDHYIECCALAPPSSYPFLSRLAGLKKPPAATSTAEFMASGSRDKTIKLWDARGTLLKTLIGHDNWVRALVFHPGGRYLLSVSDDKTLRCWDLEQDGKCVKTIGDVHERFVTCLRWAPGVVMDAPAEADGQSNGTPRKKTEAAPAVRIRCVIATGSVDMKLRIFAN
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: PRI2_YEAST
Sequence: MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSSEEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEIETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSRQLQKKQQKLEKEKLFNNGNH
What is the function of this protein?
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.  In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase.  Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48.
What are the official names of this protein?
DNA primase large subunit, DNA polymerase alpha:primase complex p58 subunit, DNA polymerase-primase complex p58 subunit, Pol alpha-primase complex p58 subunit, DNA primase 58 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: PMGT2_RAT
Sequence: MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALGQQSLDPVPGLRIDYPKALQILMEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNSSVMLPNLGSRRFQPALLDLSTVEDHNAQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAQEARLFFMEGWGEGAHFDLYKLLSPKQPLLRSQLKTLGRLLCFSHAFVGLSKVTTWYQYGFVQPQGPKANILVSGNEIRQFTRFMTERLNVSHAGAPLGEEYILVFSRTQNRLILNEAELLLELAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTALFLPRGATVVELFPYAVNPDHYTPYKTLATLPGMDLQYVAWRNMIRENTVTHPERPWDQGGITHLDRAEQARILQSREVPRHLCCRNPEWLFRIYQDTRVDIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIPWNLKYLKVREVRYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNRSLLGPFADVLVCST
What is the function of this protein?
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein.  Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).
What are the official names of this protein?
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, POMGnT2, Extracellular O-linked N-acetylglucosamine transferase-like, Glycosyltransferase-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ERPA_FRATO
Sequence: MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TRPD_STAEQ
Sequence: MTLLEKIKQNKSLSKKDMQSFIVTLFDSNIETNVKVELLKAYTNKDMGQYELTYLVEYFIQTNYPNQPFYNKAMCVCGTGGDQSNSFNISTTVAFVVASAGVPVIKHGNKSITSHSGSTDVLHEMNIKTNKMNEVEQQLNLKGLAFISATDSYPMMKKLQSIRKSIATPTIFNLIGPLINPFKLTYQVMGVYEASQLENIAQTLKDLGRKRAILIHGANGMDEATLSGENIIYEVSSERALKKYSLKAEEVGLAYANNDTLIGGSPQTNKQIALNILSGTDHSSKRDVVLLNAGIALYVAEQVESIKHGVERAKYLIDTGMAMKQYLKMGG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: LACB2_STRPQ
Sequence: MKIAVGCDHIVTYEKIAVVDYLKTQGHEIIDCGTYDNVRTHYPIFGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB 2.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: Y3492_GLUDA
Sequence: MRMLLGSFAVYAAAALCEIGGCYAWWCWRRAGAGAWVLLPGMASLALFGWLLTLVDSDTAGRTFAAYGGIYIVGAIVWLRLVEGRPVTLRDAAGVAICLAGAAIILSAGRGAER
What are the official names of this protein?
UPF0060 membrane protein GDI3492/Gdia_2889.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLAP_BACLI
Sequence: MAKTNSYKKVIAGTMTAAMVAGVVSPVAAAGKSFPDVPAGHWAEDSINYLVDKGAIVGKPDGTYGPTESIDRASAAVIFTKILNLPVDENAQPSFKDAKNLWSSKYIAAVEKAGVVKGDGKDNFYPEGKIDRASFASMLVGAYNLKEKVDGTLVTKFDDLRGHWGEEKANILVNLGISVGTGGKWEPNKSVSRAEAAQFIALTDKKYAKPENSDAKVTNVAATEPTQLTLTGTGLNKLTAEDVTLEGNKAIALEASKDGKSAVVTLSGKIAPNKELPVKVKGNTFIVKYVYEVKKLRVEQLTFDDDRADQAVVFKLNDEKGNADIEYLDIAGHDVKFVANNLDGTPANIFEGGTAESTTGKLAVGIAEGKYKVEVQVTKRGGITVSNTGIIEVKNLDAEATAIKDVVFAVDTDKAGVNYAKPLSGTDFTLNSKTLVAGEKAGIHKVVAQINKENKVVDPSAISLKSSNPGVISVKNGEIKAEAAGSATLTVKVGDVTKTFDFVVKTDTRKLTTVKANPDQLKVVDGKELPVTFVTTDQYGDPFGANSGAIKEVFPQTGVVKVLDVTTTNEGSIGTSSIKVKGENVGAGTIHFQNPNASGEGYGSLHVEVTKSNIGHEAPRLELVSKAGQKGEAADTTLGAGNTVAYQLSNYTTEGVYADAADLAGYEFRVGNDKIASAKIEGKTLKVTGKTAGVTDVILTKDGATAGHATITVTQENIQITSVKFKDVEVEQFENRKVNIDRVLDVVKSDKDDVLNGIKLNISTEHKVRIVDEGTEQGKVYLDRNDNATFDGNDVALGYVTAVKSNDTVSKEGNDLFKFLTDETATNKNDVFKGVTTAFGDKGTVIFKVMKDRVAPTTEYGTKAVTINVIKEEI
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein, Surface layer protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: SYFA_STAAC
Sequence: MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEDKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL1_RICAE
Sequence: MLASYASDPLKSRGRLYKEIPTSYRNEFERDRDRIIHTNAFRRLQYKTQVFINHEGDHYRNRLTHSLEVSTVARSVASTLNLSNDLAETIALAHDLGHTPFGHAGERALNECMREYNGFSHNAQSLKILTLLEKRYAAYNGVNLTWEVLEGIVKHNGPILGEINEYIAEYNKQNDLELSTYASAEAQIAALADDISYISHDLEDSIGAKIIDFHSLAELKYIDQHVVELKSKFKNISSSCLIYEVVRKLIHELITDLLWQTKENLNKEKITNIDEIRNLNYQIVDFTEKTNKNIKETKKFLHERVYKSNKITAISLKCTKIVQGLFKVYMDDINLLPVNWKMLIDSNETYSKARVVADYIAGMTDRFAIQEYNQLCSTSYITCF
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: CRL_YERPE
Sequence: MTLTSAHPKSKLMKRFAALGPYLREGQCQNDHFFFDCLAVCINVKLAPEKREFWGWWIELEPSAGRFTYVYQLGLFNKEGNWNAEKISDPEVQDKLESTLRSFHLRLEEMLASIDMKLEPAADFNDQPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADR_YERPY
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLAVRTNIATIFVRTAIRHHPEKAQEILARAKTVDDNAEAFTALDYGIFRGLAFASGNPIYGLILNGLKGLYTRVGRYYFSNPEARKLALTFYNKLSTLCDTESYDQVLECLRTYGKESGAIWHSMQGTMPSDLAEARR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTR8_MAGO7
Sequence: MHTYKFIQIALLFASVALAIPTPPSPPNPPPVPQLPNSETKSNRLVSHSCEFCGVVKPSGPAYLEHYHQNHREEVWGKLATPSPPNPPPVPTQKVETHAPKTHGCEWCNKVEPSGPAYIKHYKENHEDQVWGKWAGQDAKASP
What is the function of this protein?
Probable secreted effector that translocates into the nuclei of host cells to reprogram the expression of targeted genes by binding on effector binding elements in rice.
What are the official names of this protein?
Host transcription reprogramming factor 8, Secreted nuclear effector HTR8.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: PDUL_SALAR
Sequence: MDKTLLESTVHKVLDELRNRPIPLGVSNRHIHLCAADYARLFPEQAIREKKALLQPGQYAAEQTITLAGPKSQLKKVRLLGPLRNVSQVEISRTDARTLGIAAPLRMSGDLQGTPGIRLISPFAELELASGVIVAQRHIHMSPLDALIFRVAHGDTVSVAIEGSERRLIFDNVAIRVSPDMRLEMHIDTDEANAAGADDPHTFASLVARR
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: CLC6A_HUMAN
Sequence: MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL
What is the function of this protein?
Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: specifically recognizes and binds alpha-mannans on C. albicans hypheas (PubMed:23911656, PubMed:28652405).  Binding of C. albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes (By similarity).  Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production (By similarity).  Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses (By similarity).
What are the official names of this protein?
C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: KBX1_TITCO
Sequence: MERKLALLLFLGMVTLASCGLREKHVQKLVALIPNDQLRSILKAVVHKVAKTQFGCPAYEGYCNNHCQDIERKDGECHGFKCKCAKD
What is the function of this protein?
Tco 42. 14 may block voltage-gated potassium channels.
What are the official names of this protein?
Scorpine-like peptide Tco 41.46-2.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BAMC_THIDA
Sequence: MRLLPLFLMVTLAASGCGIVESKKIDYKSSNKLPTLEIPPDLVAPTADNRYAIPDTEGSGTATLSTYSAERKAAPSGTPSLLPAQDKARIERAGTQRWLVVQATPQQVWPVIKDFWQENGFIVNLESPETGVIETDWAENRAKIPQDVIRRTLGKVLDGLYSTAERDKFRTRIEAGSGGTEIYLSHRGMMEVYATEGKDKTVWQPRPADPELEAEMLRRLMLRFGVEENRAQTLLTAKQTPDQARVIRDAGGSLLEMDEGFDRAWRRVGLALDRVGFAVEDRDRSKGTYFVRYIDPDADNASKRDEGMFAKLAFWRSKKDQASPQLQIVVDEAGEGKSRVRVAGGEGRAADAATQNRIINLLHKELK
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamC.
What is the protein family that this protein belongs to?
Belongs to the BamC family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RIBA_SHIDS
Sequence: MQLKRVVEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: MCSB_ALKCK
Sequence: MSLDRFLKNAISPWMKKDGSDADIVLSSRIRLARNMSAFTFPMLSSKEEAYAVAKHVKDALGGTQGEALGKAEMLAMEDMRTNDKRMLVEKHLISPHLAEQSKYGMVLLSGDESLSIMINEEDHIRIQSLSAGFELENCLQAANAVDDWVESHLTYAYDSQYGYLTSCPTNVGTGMRASVMIHLPALAMTRQLQRILPAINQLGLVVRGIYGEGSEALGNLFQISNQITLGKTEQDIVDDLQGVVKQLIRQERVARDSLLQHSKLELKDRVFRSYGILANSYIIDSKEATRRLSDVRLGIDLGFIENTAGKILDELMILTQPGFLQQYAKTVLTPEQRDERRAALIRERLKLEHETAD
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PMM1_MOUSE
Sequence: MAVAVEGARRKERILCLFDVDGTLTPARQKIDPEVSAFLQKLRSRVQIGVVGGSDYSKIAEQLGEGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIEFRNGMLNVSPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEGWDKRYCLDSLDEDSFDIIHFFGNETSPGGNDFEIYADPRTVGHSVVSPQDTVQRCRELFFPETAHEA
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.  In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.
What are the official names of this protein?
Phosphomannomutase 1, PMM 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
Protein: CHIA_SECCE
Sequence: MGAFALFAVLAMAVTMAVAEQCGSQAGGATCPNCLCCSRFGWCGSTSDYCGDGCQSQCAGCGGGGTPVTPTPTPSGGGGVSSIVSRALFDRMLLHRNDGACQAKGFYTYDAFVAAAGAFPGFGTTGSTDTRKREVAAFLAQTSHETTGGWATAPDGAFAWGYCFKQERGATSNYCTPSAQWPCAPGKSYYGRGPIQLSHNYNYGPAGRAIGVDLLRNPDLVATDPTVSFKTAMWFWMTAQAPKPSSHAVITGQWSPSGTDRAAGRVPGFGVITNIVNGGIECGHGQDSRVADRIGFYKRYCDILRVGYGNNLDCYNQRPFA
What is the function of this protein?
Defense against chitin-containing fungal pathogens.  Binds the hyphal tips, lateral walls and septa of fungi and degrades mature chitin.
What are the official names of this protein?
Basic endochitinase A, Rye seed chitinase-a, RSC-a.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: PFDB_PYRAB
Sequence: MQNIPPQVQAMLGQLESYQQQLQLVIQQKQKVQADLNEAKKALEEIEALPDDAQVYKTVGTLIVKTTKEKALQELKEKVETLEVRLNALNRQEQKINEKVKELTQKIQAALRPPTAG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_ECOLU
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: EAF6_NEUCR
Sequence: MMDNSGPKMGAADGAAGIPYYEKQRQHLKELLNKKKLLEKRLLAQEESIYQKETEYLENTPAGNIITGFDNYTKGTANVAAQRRKTGLTDANRVFSRSSISYNPAAQQDSQTPASSAPASHAPTPVSTSFNNKDGASSAPTPTSATAGKANSKKKKAATSGGAGVEDSETDSRETKKARTNFGAVRK
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein eaf6.
What is the protein family that this protein belongs to?
Belongs to the EAF6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDI54_ARATH
Sequence: MVSTSKIKSVDFYRKIPRDLTEASLSGAGLSIIAALSMIFLFGMELNNYLAVSTSTSVIVDRSADGDFLRLDFNISFPSLSCEFASVDVSDVLGTNRLNVTKTIRKFSIDSNMRPTGSEFHAGEVLSLINHGDETGEEIVEDSVPLTGRNFDTFTHQFPILVVNFYAPWCYWCNLLKPSWEKAAKQIKERYDPEMDGRVILAKVDCTQEGDLCRRNHIQGYPSIRIFRKGSDLKDDNAHHDHESYYGDRDTESLVKMVVSLVEPIHLEPHNLALEDKSDNSSRTLKKAPSTGGCRVEGYMRVKKVPGNLMVSARSGSHSFDSSQMNMSHVVNHLSFGRRIMPQKFSEFKRLSPYLGLSHDRLDGRSFINQRDLGPNVTIEHYLQIVKTEVVKSNGQALVEAYEYTAHSSVAHSYYLPVAKFHFELSPMQVLITENSKSFSHFITNVCAIIGGVFTVAGILDSILHHSMTLMKKIELGKNF
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
What are the official names of this protein?
Protein disulfide-isomerase 5-4, AtPDIL5-4, Protein disulfide-isomerase 7, PDI7, Protein disulfide-isomerase 8-2, AtPDIL8-2.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HA2B_MOUSE
Sequence: MPRSRALILGVLALTTMLSLCGGEDDIEADHVGTYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLASFDPQGGLQNIAVVKHNLGVLTKRSNSTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTIFIIQGLRSGGTSRHPGPL
What are the official names of this protein?
H-2 class II histocompatibility antigen, A-B alpha chain, IAalpha.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLIP4_MOUSE
Sequence: MTIEDLPDIPLEGSSLIGRYPFLFTGSDTSVIFSISAAPMPSDCEFSFFDPNDASCQEILFDPKTSVSELFAILRQWVPQVQQNIDIIGNEILKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDIETAVKFAAQLIDLGADASLRSRWTNMNALHYASYFDVPELIRVILKTSKPKDVDATCSDFNFGTALHIAAHNLCAGAVKTLLELGANPAFRNDKGQIPAEVVPDPVDMPLEMADAAAIAKEIKQMLLDAVPLPCTSAKAVLPNSDHTTSRAMLTSLGLKLGDRVVIAGQKVGTLRFCGTTEFASGQWAGIELDEPEGKNNGSVGRVQYFKCAPKYGIFAPLSKISKLKDGRKTTTHTPSTRATPHARSQKVDVAHFTSRVNSGLTTSKKETASESTLTLPPSEEPKTVAENDAAQPGSMSSSSSSSSLDHKQSYPKKLTTSSGGKKTLSKSPSLPSRASAGLKSSATSAANNSHHEGALHLGERVLVVGQRVGTIKFFGTTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCSPRYGIFAPPSRVQRLSDSLDTLSEISSNKQNHSYPGFRRSFSTTSASSQKEINRRNAFAKTKTTLRRSWSSSTTAGGLEGTVKLHEGSQVLLTSSNEMATVRYVGPTDFASGIWLGLELRSAKGKNDGAVGDKRYFTCKPNYGVLVRPSRVTYRGISGSKLIDENC
What are the official names of this protein?
CAP-Gly domain-containing linker protein 4, Restin-like protein 2.
Protein: RL21_HELPY
Sequence: MSYAIFKHGGKQYKVVEGDIVLLDKMDKEPKALVELVEVLAVSKEGKLSCGKPFVNGAKIEAEVINEGRGKKVITFKKRRRKDSKTKRGFRRDFTRVRITKIVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.