PharMolix/UniProtQA huggingface dataset:
Protein: Y733_ENCCU
Sequence: MARRNGNNNFLNIMRSMLSFLDTRIESSDIDASNTPGGVFMNRLRSRLVDLISGRIGDGDDGREDDETRAPPPGRDLRGRGRKVRGSARQEVPSVEERNLVDRCNRMMNETEERPTRERRRTRAVSRGSERNGETERPRSEGVEDPVTLTTSIVVTGDGLGNTQAPSQSAEAQDETGPRSSRTVGSRGFRVVFPRIPSQELRFLFLTPQSEGSRGNIIYEIQINFDVFEASSEAPTTATKESLKKSSIVRAVEADKGCECAICMSNFIKNQRLRVLPCDHRFHVGCVDKWLLGHSNKCPVCRTAI
What are the official names of this protein?
Uncharacterized RING finger protein ECU07_0330.
Protein: MTP_PIG
Sequence: MILLAVLFLCFISSYSASVKGHTTGLSLNNDRLYKLKYSTEVFLDRGKGNLQDSVGYQISSNVDVVLLWRSPDGDDDQLIQITIKDVKVENVNQQRGEKSIFKGKKPPQIIRKENLEALQRPVLLHLIHGKVKEFYSYQNEPPAIQNLKRGLASLFQMQLSSGTTNEVDISGDCKVTYQAHQDKVTKIKALDSCTIERSGFTTRNQVLGVTSKATSVTTYKIEDSFVVAVLAEEIHALRLNFLQTIAGKIVSKQKLELKTTEAGPRLKSGKQVAAIIKAVDSKYTAIPIVGQVFQSECKGCSSLSQHWQSVRKHLQPDNLSKTEAVRSFLTFIQHLRTAKKEEILQILKAENKDILPQLVDAVTSAQTPDSLDAILDFLDFKSDSNIILQERFLYACGFASHPDEELLRALISKFKGSFGSNDIRESVMIIIGALVRKLCQNEGCKLKAVVDAKKLILGGLERAEKKEDTMMYLLALKNARLPEGIPLLLKYAEAAEGPISHLAVTTLQRYDAPFITDEVKKTMNRIYHQTRKVHEKTVRTTAAAVILNNNPSYMEVKNILLSIGELPKEMNKYMLSIVQDILRFEMPASKMVRRVLKEMVAHNYDRFSKSGSSSAYTGYIERGPHSASTYSLDILYSGSGILRRSNLNIFQYVGKTPLHAIQVVIEAQGLEALIAATPDEGEENLDSYAGLSPLLFDVQLRPVTFFNGYSDLMSKMLSASSDPISVVKGLILLIDHSQELQLQSGLKANMEVQGGLAIDISGSMEFSLWYRESKTRVKNRVTVVITGDITVDSSFVKAGLEISAETEAGLEFISTVQFSQYPFLVCLQMDRDGIPYRQFETKYERLSTGRGYVSRKRKEILVAGSEFPLHQENSEMCKVVFAPEPESSSSGWF
What is the function of this protein?
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (By similarity).  Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (By similarity).  May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity).
What are the official names of this protein?
Microsomal triglyceride transfer protein large subunit.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Note=Colocalizes with P4HB/PDI in the endoplasmic reticulum.
Protein: PEPT_CLONN
Sequence: MEAVVNKFLKYISFDTKSNEDSNAHPSTEGQMVLAKELARELKEMGMIDVSVDSKAYVMATLPANTENHVPTIGFIAHMDTAPDMSGKDVKPQFVENYDGKDIILNKEKNIVLKVKDFPEIKDYIGKTLITTDGTTLLGADDKAGVAEIMTAMEHLINHPEIKHGTVKIAFTPDEEIGAGADYFDVEKFNADFAYTVDGGTVGELEYENFNAAGVKLTIHGRNVHPGSAKDKMINSITVGNELHSMLPENEVPEHTEGYEGFYHIVAFNGTVEETKMQYIIRDFDRKKFEERKATMQKVVDTLNSKYGEGTVELQMNDQYYNMKEKVEPVHHIVDTAFKAIEEVGLVPKVVPIRGGTDGARLSFMGLPTPNLFTGGHNFHGKFEFIPTFAMSKAVDVILKIIELYSK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_RICPR
Sequence: MSQYHIPVMLSEVLAVLAPKGYESYLDCTFGAGGYSNAILNSCYCSVTSLDRDPNVIESVEKIKQDYGERFNFIKTNFADSFRKLKHKKFDGIVMDLGVSSMQLDIADRGFSFLYDGPLDMRMSVQGFSAEEFVNTADEEEIADVIYKYGNESLSRRIAKSIVEYRKTARIDSTRKLAEIVRYSIGFRKGKIDSATKTFQAIRIYINNELEELEQFLANVKNILKKDGRLVVVSFHSLEDRIVKNFFKENSEKQVARSKYAKDEIKIDPNKWLKIITPKVLTPSSQEIRLNVRARSAKLRAAKKII
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNS3_HUMAN
Sequence: MAGGMSAECPEPGPGGLQGQSPGPGRQCPPPITPTSWSLPPWRAYVAAAVLCYINLLNYMNWFIIAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGLSSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAVTMLTGNWRWALRVMPCLEAVALILLILLVPDPPRGAAETQGEGAVGGFRSSWCEDVRYLGKNWSFVWSTLGVTAMAFVTGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRYKKVIPGAEPLICASSLLATAPCLYLALVLAPTTLLASYVFLGLGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLTGLISSVLRARRPDSYLQRFRSLQQSFLCCAFVIALGGGCFLLTALYLERDETRAWQPVTGTPDSNDVDSNDLERQGLLSGAGASTEEP
What is the function of this protein?
Sphingolipid transporter.
What are the official names of this protein?
Protein spinster homolog 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROA_XANCP
Sequence: MTIKSLALQCRDAAQVLSQLSADAKQALLLAMANALDTDATQILQANQRDVDAAREKGTGAAMLDRLTLTPARLSAVGAALREVAVLPDPVGQVTRDDVRPNGIRVQKVRVPLGVIAMIYEARPNVTADAAALCIKAGNGVILRGGSEAIHSNTAIARALQGALREANVPEAALTLVEDLRRETMLELLQLSDIVDLAIPRGGEGLIRFVAEHARVPVIKHYKGVCHLFVDASADVDLAVRLLVDGKASRPSACNSLETLLVHADIAERFLPAAAAALRARNVELRGDAATRAVLPEIAAASDDDYAAEFLDLILAIRVVPDLDTALAHIRQYGSDHTEVIATQTPANAETFVQSLRSAVVMVNASSRFSDGGELGLGAEIGISTTRLHSYGPMGLEALTVERFVVRGEGQVRH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y129_CLOPE
Sequence: MRNKILKKSKSILPGLFICLIIGIIAEFLGKSFPTIGAATFAIFMGIFLGNTLFKSDKYDEGTKFSEKDLLNYSIVLMGASLNIIDIMALGFNGVFYIAILMTLTICTTYFIGRKLGFGEKYSLLMSAGNAVCGSSAIGSVSPVIKAKDSDKVIAITIVNVTGTILMILLPLITSILYNNDVLQSSALMGGILQSVGQVIGSAKFIGDPVVELATVFKIIRIIFLVVVVLVFAKIEVNEENKEEIAHHHKPTHKVRIPWFIIGFFIICILNSIGIIPGILGRTFKWISSNFEIIALAGIGMRVKIGDLVKEGPKAMLYGGLVGVCQIIFALSLINIFIK
What are the official names of this protein?
UPF0324 membrane protein CPE0129.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3357_EDWI9
Sequence: MSTENSPTDYATLTQVLQQQGVALTAAEMHGLLSGLLCGGNRDDSWLTLVHDLTNEGMAFSQHLSQPLQVLYGQTRSALEGGEFAFQLLLPGEDDASVFARADALAGWVNHFLLGLGMMQTKLGQVKGDVGESIDDLRNIAQLGYDEDEDQETLAHSLEEVAEYVRMAAMLCHGEFSCSGGPASDTPRLH
What are the official names of this protein?
UPF0149 protein NT01EI_3357.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: PEX13_HUMAN
Sequence: MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPSQQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL
What is the function of this protein?
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (PubMed:9653144, PubMed:8858165, PubMed:28765278).  The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity).  Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (PubMed:9653144, PubMed:8858165, PubMed:28765278).  Involved in the import of PTS1- and PTS2-type containing proteins (PubMed:9653144, PubMed:8858165).
What are the official names of this protein?
Peroxisomal membrane protein PEX13, Peroxin-13.
What is the protein family that this protein belongs to?
Belongs to the peroxin-13 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: CFA46_HUMAN
Sequence: MDLVITQELARAESQQDAASLKKAYELIKSANLGKSEFDPSESFSPDLFVLCAEQALKMRQPEVSEDCIQMYFKVKAPITQFLGRAHLCRAQMCAPKSAENLEEFENCVTEYMKAINFAKGEPRYYFLVYNASVLYWQMVRPFLKPGYRHHLIPSLSQIINVLSQTEEEDKEWRAELMLELLECYLQAGRKEEAARFCSTAAPFIKSHVPQKYRQIFSVMVRHELMDELQLKEEKKNSISLSVTFYINMLKAKAEQNDLPGDISVILRKAYRHLGHYNHQRFPSISEEKMLLLFELARFSLTLKCMEISSACLSDLKKMESKDPGKLIEMECLECESEALRLESKMKVYNRAAVEAQLDIIQRLDVALQRAVRLGDPRVIHVVCATQWNTCLPLLQHNLRHHLRKPLAGVADVLEKLDSLMTLLRCQVHMEMAQIEEDEDRLEPATEHLRKAARLDSLGLYRDRIQMASTRLRLCTTLYQAPERAEDKAIMAVEQAKKATPKDSVRKKRALLVNAGLALAPDAFQIVLDSENEAKVSTGKNRGRFTYLCAKAWHHTVSVDKAAGHLRRLGNENDKERIQIWAELAKVARKQGVWDVCRTASRFCLLYDNVKVKKLRLRRGKKKRGRDGSVQDTWSQPEVVLQRQVCPDLLRKFAEVGFIHAEATVHLLRSEGVELNDRAIPPEDLSQHPAGYVPEPPEVNAEWITYRTWIESLSRCAMNNWLRSAEIGQEIQEAWIVQNAVVYVLNHNHHLILAGRQKELVDALYHLLSIVKATGHSGDPVMLVTLCNTLARGLIISWIPVQAAEKSRKFMRPNAFHSPLDAGATSEIKTAVEVCEFALNLTNGSAPEETVPTGTRQQLIATWVKAKQLLQQQIGPRLGTEEQGTNEDVSSVTRVLVALEMYSCNGLGLMDFTVPSLAQLVKMASECNWSDPLVELQTLTRLTHFAHAARDHETTMACAHRALEMGIKYLKKFGPEESRLVAEMLCTATAIQGRSIMENLKGRKQLRLVAAKAFTESARFGGIAGSSALVMLAARHYWNAWLPLLSSAVYRKKAKGALKRLIGIINKTEARKQEKGKTLLLHQWPTADFQGGGTTEGYFLPGAEDDLALRAALYGLLFHSHADQDDWEGGLKVLDEAVQVLPRTAHRLLIFKHMVIVKAKLGQNFSMEIQKFKAESEDYLARMWHRLALNSPSVSGELACYNNAIQALQKPEMEWQKVEYLMEFGQWLHHRHFPLEDVVFHLRWAVEILLAMKPPGDVPEPQPTPDGEYVAVEMPPRSPVSEAEEAVSLEQLRSVRQLEALARVHILLALVLSPGAEGYEDCCLAAYAFFRHIWQVSLMTAGKSVLENRPLAATSSHLLLPKKEKENERSKEKEKERSKEKENERSKEKDKEKGKEEKVKEPKQSQSPAPIKQLEDLPMSIEEWASYSCPEEVLSVLKQDRSDSTVNPSSIQKPTYSLYFLDHLVKALQKMCLHELTVPVLQLGVLISDSVVGSKGLSDLYHLRLAHACSELKLREAAARHEEAVGQVCVSELEQASCRKEIALKKEKNKEPLLEESLPALNEQTLPVQPGEIKPLDAKDKILKMNGETGRDLDGTSFPHLWMLKAEVLLEMNLYQPARLLLSEAYLAFQELDEPCAEAQCLLLLAQLANKEKNYGQAKKMIAQAQHLGGSEEFWYNSTLTLAEALLSMEHSGREATVCHIFQKLINAFKILKKERPNRLPLLEFMITDLEARCLSLRVRVAQHSAVTEPTECSLLLKEMDDGLLEIERKFIDCGCKENCVDVKLERAKIKRLRAQNEKDEEQKTAYYLEAYGLAQGAVAEEEGRLHSIQGLYGLAQGAMAEEEGRLHSVQGLLSLQDLQNVNTPLMRKLARLKLGLVEMALDMLQFIWEEAHGQQSEQGSLEKLLADYLQNTSDYTSVGLQWFTLKRTLAHGALAQLGSLQPLSVGCVEIRARLLGLAGRALHLLAMQADPVHPTCYWEAGPSVGAKLSGLKSLELEVEEEGATKSSRDPPASRAAPEEHCRRGEDLKRRMVLAQQYLAQASEVLLQCLQVALGSGLLDVAAAASLEMVECVGTLDPATTCQFLALSQSCSASETMRDVLLAATANTSSSQLAALLQLQHQLRCQDRTTTSLGARVEQRLAAVSKAWQNLCVTEQHFNLLNEMPPTFWILFLHLSGDRSRLYGAAYEKPKFITAAKGKVQAVGGSCKVMRLAISPTAFSHLLACAQQFRKQTQAQVYSEDMALNIGSEPEGLQVEEKERPVQRLSSVLGPLEELLQPLFPLLSLSKARVQTPAVVADSGKSKGKDKERKTSTGQHSTVQPEVADKIVLVADRHLLELPLEGLSVFDEGTISSVSREFSLQMLWNRLHKEETEGGVKKEGRSRDPKKRSLAKKGRKGSIPRTIPPDCIIVDSDNFKFVVDPYEEAQGPEMLTPVSITQDILERFQDTFTSRWAGHLGSKHFPSQAQWEQALGSCSGFFFYGMESFLSHILVERLVAMNLQECQVAVLLDLARSYQSLKRHMESVEHRRSVGRWEANWRNSASPSEDEWRRGGEPRRGFSDLEGQAAAAPKLRAPSHHAQLGPVWAAAPSHRVVQAWTCLPSAAGAPALASALGSAPLPTHPHLPAPIPSSQLALPFLGLSPALGAASARDPPPATSRKAAAWTSSSACLCAPWGLRRGWSCVSSRGQDKGGLPLAALVLSCLDQKTIQTVSLFLI
What is the function of this protein?
As part of the central apparatus of the cilium axoneme plays a role in cilium movement.
What are the official names of this protein?
Cilia- and flagella-associated protein 46, Tetratricopeptide repeat protein 40.
What is the protein family that this protein belongs to?
Belongs to the CFAP46 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: PSTB2_VIBVU
Sequence: MNKFDIENLDLYYGENQALKAINLPIPVRQVTALIGPSGCGKSTLLRCLNRMNDLIEGVKITGKLAMDGEDIYGNVDVADLRIKVGMVFQKPNPFPMSIYENVAYGLRAQGIKDKKHIDEVVERSLRGAALWDEVKDRLKSHAFGLSGGQQQRLCIARTIAMEPDVILMDEPTSALDPIATHKIEELMEELKKNYTIVIVTHSMQQARRISDRTAFFLMGELVEHNDTQVIFSEPSDDRTRGYVNGDFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RB27B_HUMAN
Sequence: MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIPDTVNGGNSGNLDGEKPPEKKCIC
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381).  Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604).  May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
What are the official names of this protein?
Ras-related protein Rab-27B, C25KG.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Late endosome.
Protein: CCD22_DICDI
Sequence: MDEADGIILITLKDLGCEIEENETIKNFDSEMVYKCILAYLRVINEQKVINLTNTLPKNMSARVNACSLIANIIKDSGYRSELSYHNLLYPNVNDIRKIFIFLGQLLPKKEVESGGVSIQKLEDQICQYLQGCVKESWIPYFCPFSKRIPGNYSTATLFTTTGGNLRIPSRGRQLKVTPGLEQYYSQYLEPLTLQTNRFEDIAPSVFEYNLSIYAEAQERDNEWNDKGVSSGMNPIDYRKNKQKQVLSKMNDSIRQSIIDGGNNQISSNCNSGDSFLDIISEFRGNSLDVGGQFNRKKAFTNELNNNNNNNNDSTTNTNKVETEIETEEQRQLKRQAEIDALQSQIDEISESIQLHNKEMLDFLSLMRQSESENLEQDQQREVLEKQYKIKKKTFSLLDDAEGNMKELQSLCNQTSSNLLEMSGEWEKVRKPIIEKYRSLKDKQNNQADETKSKLDRIKEMRILIKKLVSEVQQKDDQFQQLQDQYKQAPKDSNRSQYTRRILETVKNIKKQKVDIDKVLLDTKNLQKEINTITDTAVRTFELVKDLLYNDAKKDQTAKQAIKSFAIIDDKFQKLFKTIDETGNFQNNILNLNSKIEHVSQKTNTLNSDRVVQDLKNIKSENQSLIKQIKTLIETKN
What are the official names of this protein?
Coiled-coil domain-containing protein 22 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
Protein: NEU1_ONCKE
Sequence: MFGTSVSALCLLFLLSVCTACYISNCPIGGKRSALAFPSRKCMACGPGDRGRCFGPNICCGEGMGCYVGSPEAAGCVEENYLPSPCEAGGRVCGSEEGRCAAPGICCDVEGCSIDQSCTEEDEAEYISQSVSSSHGHDLLMKLLNMISHTPPHRVHK
What is the function of this protein?
Isotocin causes contraction of smooth muscles.
What are the official names of this protein?
Isotocin-neurophysin IT 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3A_SULIK
Sequence: MSAKGGTIKDKWKMKKWYSIIAPKVFGEVSLGSTPAYDVTQTIGRRVETTLYDLTGDFSQVYVHLYFKIVSNEGDRLITRFVGHELSRDYLRSLIRRKSSKVNSVFDVTTKDGYVVRVKGLVLTTYKCHQSQKTAIRKIINETISKKASELTFDDFTQEVVFGRLANEIFEATKKIYPLRKAEIEKTKVLKVPENLGKQVESSSVSSG
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: RL11_MYCGI
Sequence: MPPKKKVTGLIKLQIQAGQANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGNVIPVEITVYEDRSFTFALKTPPAAKLLLKAAGVPKGSGEPHKTKVAKVTWDQVREIAETKKEDLNANDIDQAAKIIAGTARSMGITVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RBL_EMIHU
Sequence: MSQAVESRTRIKSERYESGVIPYAKMGYWDPEYVIKDTDILALFRCTPQPGVDPVEAAAALAGESSTATWTVVWTDLLTACDLYRAKAFRVDPVPSAADTYFCYIAYDIDLFEEGSLANLTASIIGNIFGFKAVKALRLEDMRFPVALLKTYQGPATGVVVERERMDKFGRPLLGATVKPKLGLSGKNYGRVVFEGLKGGLDFLKDDENINSQPFMRYRERFLYSMEGVNHAACLTGEVKGHYLNTTAATMEDMYERANFARDLGSVIVMIDLVIGYTAIQSMGKWSRDNDVILHLHRAGNSTYSRQKNHGMNFRVICKWMRMSGCDHIHAGTVVGKLEGDPLMIKGFYNTLLDTKTEVNLPQGLFFAQDWASLRKCVPVASGGIHCGQMHQLINYLGDDVVLQFGGGTIGHPDGIQAGATANRVALECMVLARNEGRDYIAEGPQILRDAAKTCGPLQTALDLWKDITFNYASTDTADFVETATANV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPF_MESM1
Sequence: MLELGIFSSNTQNIGQSISERFAGIFPSWPIMLATLVSFTILLVVLTKLIYKPVKKMMKNRRDFIQNNIDESTKQVEKSNELLEKSNIEILDAKIKANTIIKDAQILAEEIKNNSIKDAKDKSKQLLEETKIYIRQQKVLFAKESKKEIVEIAGEMTKKILSESDVKLEDSKFLENLLKNDITK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
Protein: TRMB_STRPC
Sequence: MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: GATA_BRUSU
Sequence: MSELTALTIAEARDKLKAKAITATELTDAYLSAIDAANDAINAYVAVTHDQARSMAKASDERIAKGEAGALEGIPLGVKDLFATKGVHTQACSHILDGFKPEYESTVTANLWADGAVMLGKLNMDEFAMGSSNETSYYGPVKNPWRAKGSNADLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRVSRWGTVAFASSLDQAGPIARDVRDAAILMKSMASLDLKDTTSVDLPVPDYEAALGRSVKGMKIGIPREYRVDGMPGEIEELWQKGIQYLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIADMYEQTRAAGFGKEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKKDFEDVFAKGVDAILTPATPSAAFGLADEVLANDPVKMYLNDIFTVTVNMAGLPGIAVPGGLNGQGLPLGLQLIGRPFEEETLFQAAHVIEQAAGRFTPAKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GLYA_HALOH
Sequence: MEFLKKVDPDIFGLIEEEDQRQRRNIELIASENFVSDAVMEAAGSCLTNKYAEGYPHKRYYGGCEVVDKVEELAIARARELFGAEHVNVQPHSGSQANQAVYFATVPPGGTILAMDLTHGGHLTHGSPVNMSGKYYNFIHYGVTREEEVIDFDQVRELARKHQPDLIVAGASAYPRIIDFEVFREIADEVGALFMVDMAHIAGLVAAGLHPSPVPVADFVTTTTHKTLRGTRGGLILCKGEHAKKIDKAIFPGLQGGPLLHIIAAKAVTFKEALQDEFKGYQKQIVSNAKTMAAELKNYGFRLVSGGTDNHLMLVDLTNMDITGKDAETALDKVGITVNKNTIPFEKRSPFVTSGIRIGTPAVTTRGMKEKEMKLIAKLIYQTLKNINDEGRLTEIRQEVYRLSERFPKTAE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_MARMS
Sequence: MNLMNPTTGPVAITSNGLVPMVIEQTARGERSFDIYSRLLKERVIFLVGQVEDHMANLVVAQLLFLESENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAASMGALLLTAGAAGKRYCLPNSRVMIHQPLGGYQGQASDIEIHTREILSIKHKLNEIISFHTGKPIEQVALDTDRDNFMNPQTAKDYGLIDEILQKRTV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANR16_MOUSE
Sequence: MALPGDPRRLCRLVQEGRLRDLQEELAVARGCRGPAGDTLLHCAARHGRQDILAYLVEAWSMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLDVIQDLVEHGANPLLKNKDGWNSFHIASREGHPVILRYLLTVCPDAWKTESNIRRTPLHTAAMHGCLEAVQVLLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLEQHKACSSAADSMGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALHYAAKEGQTNTVQTLLSLGADINSTDERNRSVLHLACAGQHVACTRLLLQSGLKDSEDLTGTLAQQLTRSVDILQDFDHDVKS
What is the function of this protein?
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity (PubMed:29769718).  Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides (PubMed:29769718).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 16.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVB_PSEP1
Sequence: MIEADRLIAASGRDREEVQDRAIRPLSLDEYIGQPVVREQMALFIQAARGRGESLDHTLIFGPPGLGKTTLANIIAHEMGVSVKSTSGPILERPGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNDKDLSTIVSRSANILGLAIEDQGAYEIARRARGTPRIANRLLRRVRDYAEVRGKGQITKAVADMALNLLDVDERGFDHSDRRLLLTMIEKFDGGPVGVDNLAAAISEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPGRLGEGGDFSGPGDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.