PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_IPNVS
Sequence: MSDIFNSPQNKASILNALMKSTQGDVEDVLIPKRFRPAKDPLDSPQAAAAFLKEHKYRILRPRAIPTMVEIETDAALPRLAAMVDDGKLKEMVNVPEGTTAFYPKYYPFHRPDHDDVGTFGAPDITLLKQLTFFLLENDFPTGPETLRQVREAIATLQYGSGSYSGQLNRLLAMKGVATGRNPNKTPLAVGYTNEQMARLMEQTLPINPPKNEDPDLRWAPSWLIQYTGDASTDKSYLPHVTAKSSAGLPYIGKTKGDTTAEALVLADSFIRDLGKAATSADPGAAAKKVLSDFWYLSCGLLFPKGERYTQKDWDLKTRNIWSAPYPTHLLLSMVSSPVMDESKLNITNTQTPSLYGFSPFHGGINRIMTIIREHLDQEQDLVMIYADNIYILQDNTWYSIDLEKGEANCTPQHMQAMMYYRLTREWTNEDGSPRYNPTWATFAMYVGPSMVVDSTCLLMNLQLKTTGQGSGNAFTFLNNHLMSTIVVAEWHKAGRPNPMSKEFMDLEAKTGINFKIERELKDLRSIIMEAVDTAPLDGYLADGSDLPPRVPGKAVELDLLGWSAVYSRQLEMFVPVLENERLIASVAYPKGLENKSLARKPGAEIAYQIVRYEAIRLIGGWNNPLIETAAKHMSLDKRKRLEVKGIDVTGFLDDWNTMSEFGGDLEGISLTAPLTNQTLLDINTPETEFDVKDRPPTPRSPGKTLAEVTAAITSGTYKDPKSAVWRLLDQRTKLRVSTLRDHAHALKPAASTSDFWGDATEELAEQQQLLMKANNLLKSSLTEAREALETVQSDKIISGKTSPEKNPGTAANPVVAYGEFSEKIPLTPTQKKNAKRREKQRRN
What is the function of this protein?
RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA.  May also contain guanylyl and methyl transferase activities (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, RDRP, Protein VP1.
What are the subcellular locations of this protein?
Virion. Note=Minor amounts are incorporated in the virion.
Protein: ATPA_STRP1
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MSHA_COREF
Sequence: MRVAMISMHTSPLQQPGVGDSGGMNVYILSTGTELARQGVEVDIFTRATRPSQGEVVQVAPNLRVINIVAGPYEGLAKEELSTQLAAFAGGVLEFTRRGGIEYDLIHSHYWLSGQVGWLMRDLWRIPLVHTAHTLAAVKNSYRADEDTPESEARRICEQQLVDNADVLAVNTQEELADLVHHYDADPDRISVVSPGADIALYTPGNDRATERSRRELGVPLHAKVVAFVGRLQPFKGPQVLIHAVAELLERDPQRNLRVLICGGPSGPSATPETYRNLAVELGVDKRIRFLDPRPPEELVAVYRAADIIAVPSYNESFGLVAMEAQATGTPVVAARVGGLPVAVAEGETGLLVDGHDPALWADTLATLLDDDETRIRMGQDAVEHARNFSWAATATQLSSLYSEATTAECDGGIPRRADGARWD
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: TUS_CROS8
Sequence: MARYDLVERLNVTFRELEHALMEMRDGLADCRLLAARVFSLPEVEKGKEHDPLLTISVTQKIGKEAQEAALRHFTHLFIQQQSEKRSSKAAVRLPGAVCFSVDDAQHEALHALADKINALKTQLEEIITVESGLPSTQRFEWVHRYLPGLITLNAYRRLTVLDNPATLRFGWANKHIIKNLTRDDVLAMLERGLKAPRAVGGLTKEQWHARLTQEYNDIAALPQKARLKIKRPVKVQPVARVWYAQNQRQVQYACPSPLIVLCHETRGGAVPDIGELLNYDAENVQHRYKPQAEELVMMIPRLHLYLAP
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSPC_KLEPN
Sequence: MSKGIKMHNSVMRLTIPNKKIINYAPHIVTSIILFFICQQLAQLTWKIILPVNFTDNALSSADMTSPAAPSAETALPRFTLFGLAEKTSASAPGGNLDQAPVSALRLRVTGLLASTDPSRAIAIMMKGNQQVSLGIGDNTPGGEAKIIAISPDRLIVNYRGRNEAIPLFNDPPAVGKNSAAPPARHLAQELRAQPQNILHYLNISPVMVNDKLSGYRLNPGKDPALFRQSGLRENDLAIALNGLDLRDKEQARQVLAQLPELTEITLTVERDGQKNDIYLALRDE
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.  Required for the translocation of pullulanase.
What are the official names of this protein?
Type II secretion system protein C, T2SS protein C, General secretion pathway protein C, Pullulanase secretion envelope PulC.
What is the protein family that this protein belongs to?
Belongs to the GSP C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRPV6_MOUSE
Sequence: MGPLQREDRPALGGANVAPGSSPVGVWHQPQPPKEPAFHPMGWSLPKEKGLILCLWNKFCRWFHRQESWAQSRDEQNLLQQKRIWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLMQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIITYAFMVLVTMVMRLTNVDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSVTYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDGLYSEDLEKDSGEKLETARPFGAYLSFPTPSVSRSTSRSSTNWERLRQGALRKDLRGIINRGLEDGEGWEYQI
What is the function of this protein?
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:12765696, PubMed:12601087, PubMed:12574114, PubMed:14736889, PubMed:15123711, PubMed:17129178).  Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (PubMed:17129178, PubMed:22878123).  The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification.  Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation (PubMed:15123711).  In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner (PubMed:12601087).  Heteromeric assembly with TRPV5 seems to modify channel properties.  TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (PubMed:12574114).
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 6, TrpV6, Calcium transport protein 1, CaT1, Epithelial calcium channel 2, ECaC2.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOC_LACDA
Sequence: MIDVNKFESMQIGLASPNKIRSWSYGEVKKPETINYRTLKPEKDGLFDERIFGPTKDYACACGKYKGVRYKGIVCDRCGVEVTTSHVRRERMGHIELAAPVTHIWYFKGIPSRMGLVLDVSPKQLEEVIYFAAYIVIDPGDTGLEAKQLLTEAEYREEKAKYGNRFVAKMGAEAIRDLLKQVDLDKEVTALKAELQTLKGQKRTRAIRRLDILDAFRNSGNKPEWMVMETVPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKKLLDMHAPGLIVQNEERMLQEAVDALIDNGRRGRPVVGPGNRPLKSISHMLKGKQGRFRQNLLGKRVDYSGRSVIDVSPELKFYQCGVPRPMALELFRPFVMRELVRRGIASNIKNAKRKIDREDDDIWDVLEYVIKERPVLLNRAPTLHRLSIQAFEPVLVPGKALRLHPLACEAYNADFDGDQMAIHVPLSDEAVAESRLLMLAAHHILTPKDGTPIVTPSQDIVLGNYWLTQAEIGREGEGMIFATPEEATIAYNNGDIHYHTIIGVSAASMPKKDWGAGHEDSVFVTTYGRLVFNSLFPDDYFYINEPTQDNLKQPMADKYFLEDGQDIQDKIAEIGQDLVATPFKKGFLGDTISEIYKRYRVQRTSEYLDDLKEMGYSASTISGLTIGMADIPETKTKDALVAEARKQVKQVSKMFRRGKLSDKERHDNIIKIWTDCKDAVQQEIAEFKDQKNPISVMQQSGARGNISNFTQLAGMRGLMATPSGELFEIPVISNFKEGLTVLELFMSTHGARKGMTDTALKTAQSGYLTRRLVDVAQDVIIREDDCGTDRGITAKAIVDKDAGLIESLYDRLVGRFTNRTIRDPQTGEVICSKGVLMDEQMAQKIVDAGVQEVQIRSILTCNTSHGICRKCYGRNLATAEEVEIGEAVGTVAAQSIGEPGTQLTLRTFHTGGVAGAEDITQGLPRVQELFEARNPKGRAVISEVDGVVDKIESNAAEHLQEITVKGKIDTRVYTIPYTAKPAVQEGDEIHRGDKLIPGSIDPKELIKVTDTLTTEEYILAEVQKSYRTQGVDLADKHAEVLTRQMLQKVRVLDPGETDILPGEVMDIAEFRDRNRDVIISGGIPATAQAYILGITKAALETNSFLSAASFQETTRVLTDASIRGKNDPLLGLKENVIIGKIIPAGTGMPIYRDQVPKADVQQPDSVYSIADLEKKMEDENKETESK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PSA7B_ORYSI
Sequence: MARYDRAITVFSPDGHLFQVEYALEAVRKGNAAVGVRGSDTVVLGVEKKSTPKLQDSRSVRKIASLDTHIALACAGLKADARVLINRARVECQSHRLTVEDAVTVEYITRYIAGLQQKYTQSGGVRPFGLSTLIVGFDPYTDKPALYQTDPSGTFSAWKANATGRNSNSMREFLEKNYKETSGKETIKLAIRALLEVVESGGKNIEIAVMTQKDGLRQLEEAEIDEYVAEIEAEKAAAEAAKKGAPKET
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-B, 20S proteasome alpha subunit D-2, 20S proteasome subunit alpha-4-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YKFH_ECOLI
Sequence: MKIISKRRAMTIYRQHPESRIFRYCTGKYQWHGSVCHYTGRDVPDIAGVLAVYAERRQDRNGPYTCLMSITLN
What are the official names of this protein?
Uncharacterized protein YkfH.
What is the protein family that this protein belongs to?
Belongs to the YeeT/YkfH/YpjJ family.
Protein: Y857_RICTY
Sequence: MVNFNQFLKQAQSMQKKMQEAQEQMANTRYTGKAGGMLVEIIITGKGEIEKVSIDESLLKIEEKEILEDLIKVAFNDAKQKCDEDSQNSLSGALNGMSLPPGFKIPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RT0857.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CBLN2_RAT
Sequence: MPAPGRGPRGPLLSMPGRRGALREPADFGSSLGAALALLLLLLPACCPVKAQNDTEPIVLEGKCLVVCDSSPSGDGAVTSSLGISVRSGSAKVAFSATRSTNHEPSEMSNRTMTIYFDQVLVNIGNHFDLASSIFVAPRKGIYSFSFHVVKVYNRQTIQVSLMQNGYPVISAFAGDQDVTREAASNGVLLLMEREDKVHLKLERGNLMGGWKYSTFSGFLVFPL
What is the function of this protein?
Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity).  Essential for long-term maintenance but not establishment of excitatory synapses (By similarity).
What are the official names of this protein?
Cerebellin-2, Cerebellin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: PT1_LISMO
Sequence: MAKELKGIAASDGIAIAKAYLLVEPDLSYEKTEVTDVESEVKRFESALEVSRTELSMIREKAAKDLGEDKAQIFDAHLLVLNDPELTGPIEESIKNSKTNAETALQETTDMFIGMFESMDNEYMRERAADIKDVRKRVLSHLLGVTIPNPALIDEEVVVVAADLTPSDTAQLNRNFVKGFVTDIGGRTSHSAIMARSLEIPAVVGTKEVTASVAKNDIVIIDGLEGNVIIHPTEEQIAHYEKIKSDFALQQAEWDKLKNEKTVSKDGVHVELAANIGTPNDLEGVISNGGEAVGLYRTEFLYMGRDNFPTEEEQFEAYKAVVSGMDGKSVVVRTLDIGGDKTLPYLELPEEMNPFLGFRAIRLCFANEELFRTQLRALLRASVYGNLKIMFPMIATVNEFRQARDILLDEKAKLKAAGTEVSDSIELGIMIEIPAAAVLADQFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLVKMVIDASHKEGKWTGMCGEMAGDQTAVPLLLGLGLDEFSMSASSILKSRSLIKRLDQSEMVKLAEEALNKSTAEEVVELVEKYTAE
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT1_CORGL
Sequence: MCDGNRRWAREAGFTDVSHGHRVGAKKIGEMVRWCDDVDVNLVTVYLLSMENLGRSSEELQLLFDIIADVADELARPETNCRVRLVGHLDLLPDPVACRLRKAEEATVNNTGIAVNMAVGYGGRQEIVDAVQKLLTIGKDEGLSVDELIESVKVDAISTHLYTSGQPDPDLVIRTSGEQRLSGFMLWQSAYSEIWFTDTYWPAFRRIDFLRAIRDYSQRSRRFGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ZIPA_XANC8
Sequence: MSDMAMIRIGILIAGLLLVAAIFLFGRPKKSPQGRRVDKDDTQPRERREPVISSGVDADGMPFERSDTGAEQSELELDDQDGAGGNDVGKRPNQDFDKIVSLFVAAKAGQVLRGEDVVVAAEKTGLVFGHMNVFHRLVEGHPERGPIFSMASILKPGSFDMANIREMQTPAIAFFLTLPAPMTALDAWEKMLPTVQRMAELLDGVVLDDSRNALGRQRVAHIRDELRAYDRQHQAPPLTKSPRW
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: SYVNB_XENLA
Sequence: MTGASLALTASVVAHAYYLKNQFYPTVVYLTKSSPSMAILYIQAFVLVFLLGKFMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHFRILALMLLLGVLDAFFVSHAYNSLVTRGASVQLVFGFEYAILMTMILAVFIKYILHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMVKVHTFPLFAIRPMYLAMRQFKKAVTDAVMSRRAIRNMNTLYPDATAEELQAMDNVCIICREEMVSGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPTQPQTPAEQQNQHQAQQQPTPVVPPQPNFPPGMLPPFPPGMFPLWPPMGQFPPVPGAPVGNPPDEANPGSSSGSSARAGETSNVGSESHPGAALPGFPFPPPFLGMSILPPFGLPPMPMPPAGFAGLTDEELRAMEGHERQNLEARLQCLQNIHTLLDAAMLQINQYLTVLASIGPPQPPVSSSSSSSASASTEPTTSSVSEPVIDTSSIVTTDSSQQSASPVPVNVETLGGAEGGETPTEEPDNVELRRRRLQKLETTDSQ
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation.  Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Also promotes the degradation of normal but naturally short-lived proteins.  Protects cells from ER stress-induced apoptosis.  Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase synoviolin B, RING-type E3 ubiquitin transferase synoviolin B, Synovial apoptosis inhibitor 1-B.
What is the protein family that this protein belongs to?
Belongs to the HRD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ILVC_SALPK
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RCCR1_ORYSJ
Sequence: MLQLRSPPPATSSPSSAVSFPTLAPRLLPLRRRRRGAGSQLGGKTSSAVRASSAAAPGATEPEVMVEVAHREVARALASLAEARLGARLLPSAVPPDVAEFRSGGGAGNAVGSLDVRRGAPGSTIDFMLQSSLHCKVPNGAIDITSLLIFLNASTDAPHFLMEFIQGSPTSIVVLLDLLPRKDLALHPEYIERYYENTQVDKQREKVEELPQARPYRSRSLFVRSTFSLTAILMSIDCGQGGEGTLEEIVRGQLATAARALLQIWLDSCADHTSEMEEGERENMIKRDQIVRSKSIEVDLTSNLPRMFGPDVADRVIAEIQKAFGVQEA
What is the function of this protein?
Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC).  Works in a two-step reaction with pheophorbide a oxygenase (PaO) by reducing the C20/C1 double bond of the intermediate, RCC.  Belongs to the chlorophyll catabolic enzymes (CCEs) (By similarity).  May play a role in senescence and response to wounding (PubMed:21807436).
What are the official names of this protein?
Red chlorophyll catabolite reductase 1, chloroplastic, OsRCCR1, RCC reductase.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVC_CAMFF
Sequence: MAITVYYDKDCDLSLIRSKKVAIIGFGSQGHAHAENLRDSGVDVVVGLNPKGKSWAKAEAKGFKVMSVSEATKYADLIMILTPDEFQADIFKAEIEPNLSEGNAIAFGHGFNIHYGQIIPPKGIDCIMIAPKAPGHTVRNEFVNGGGIPDLIAVSQDATGKAKDLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLCALINAGFETLTEAGYEPEMAYFECLHEMKLIVDLIYQGGMADMRYSISNTAEYGDYVSGVRVVNESSKAAMKAILKEIQDGTFAKNFILERKAGYTKMNAERKISEASLLNKTGEKLRGMMPWINKGRLVNKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LEUD_PHEZH
Sequence: MEAFTRLDAKAAPLPLANIDTDQIIPKQFLKTVERAGLAKGLFYDLRFDEQGREKPNFVLNRPEYKGAGVLVAGDNFGCGSSREHAPWALMDFGIRCVISTSFADIFYGNCFQNGLLPVVLKAEEVQQLMDEARGGNHVVSVDLEAQTVTSPSGAVFRFEIDPQRKDKMLRGLDAIGETLQSQKDIDVYEMKRALAQPWLEGA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: LEPA_CHLPN
Sequence: MKEYKIENIRNFSIIAHIDHGKSTIADRLLESTSTVEEREMREQLLDSMDLERERGITIKAHPVTMTYLYEGEVYQLNLIDTPGHVDFSYEVSRSLSACEGALLIVDAAQGVQAQSLANVYLALERDLEIIPVLNKIDLPAADPVRIAQQIEDYIGLDTTNIIACSAKTGQGIPAILKAIIDLVPPPKAPAETELKALVFDSHYDPYVGIMVYVRIISGELKKGDRITFMAAKGSSFEVLGIGAFLPKATFIEGSLRPGQVGFFIANLKKVKDVKIGDTVTKTKHPAKTPLEGFKEINPVVFAGIYPIDSSDFDTLKDALGRLQLNDSALTIEQESSHSLGFGFRCGFLGLLHLEIIFERIIREFDLDIIATAPSVIYKVVLKNGKVLDIDNPSGYPDPAIIEHVEEPWVHVNIITPQEYLSNIMNLCLDKRGICVKTEMLDQHRLVLAYELPLNEIVSDFNDKLKSVTKGYGSFDYRLGDYRKGSIIKLEVLINEEPIDAFSCLVHRDKAESRGRSICEKLVDVIPQQLFKIPIQAAINKKVIARETIRALSKNVTAKCYGGDITRKRKLWEKQKKGKKRMKEFGKVSIPNTAFIEVLKLD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUSG_MYCTO
Sequence: MTTFDGDTSAGEAVDLTEANAFQDAAAPAEEVDPAAALKAELRSKPGDWYVVHSYAGYENKVKANLETRVQNLDVGDYIFQVEVPTEEVTEIKNGQRKQVNRKVLPGYILVRMDLTDDSWAAVRNTPGVTGFVGATSRPSALALDDVVKFLLPRGSTRKAAKGAASTAAAAEAGGLERPVVEVDYEVGESVTVMDGPFATLPATISEVNAEQQKLKVLVSIFGRETPVELTFGQVSKI
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: 6PGD_STAES
Sequence: MTQQIGVVGLAVMGKNLAWNIESRGYSVSVYNRSRQKTDEMVKESPGREIYPTYSLEEFVESLEKPRKILLMVKAGPATDATIDGLLPLLDDDDILIDGGNTNYQDTIRRNKALAESSINFIGMGVSGGEIGALTGPSLMPGGQKDAYNKVSDILDAIAAKAQDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKDLLGMSHKEISQTFKEWNAGELESYLIEITGDIFNKLDDDNEALVEKILDTAGQKGTGKWTSINALELGVPLTIITESVFARFISSIKEERVTASKSLKGPKAHFEGDKKTFLEKIRKALYMSKICSYAQGFAQMRKASEDNEWNLKLGELAMIWREGCIIRAQFLQKIKDAYDNNENLQNLLLDPYFKNIVMEYQDALREVVATSVYNGVPTPGFSASINYYDSYRSEDLPANLIQAQRDYFGAHTYERKDREGIFHTQWVEE
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: WRK19_ORYSJ
Sequence: MVELCGGEGEGQIMLATELAQLRAMARELEAKMDPDRVAARELCRALASSVDRSIRLAASCFPPPEHPPPAAGNAGRDAAFKKRKGMAKVRRQVRVTSVQDTASLDDGLSWRKYGQKDILGAKYPRAYFRCTHRHTQGCNATKQVQRADGDPLLFDVVYLGDHTCGQAAVAAAAQSAPPEHAGQEQQRQSSLLAAGTEGIHQQVVAEPMAAPFLFTSTAAGGVDDGYFSFISPANSDCQFSSDFSAGSVGVDMDHEARFEDLFSSTLEFFQSEIQNL
What is the function of this protein?
May play a role in defense responses.
What are the official names of this protein?
Transcription factor WRKY19, OsWRKY19, WRKY transcription factor 19.
What is the protein family that this protein belongs to?
Belongs to the WRKY group III family.
What are the subcellular locations of this protein?
Nucleus.