PharMolix/UniProtQA huggingface dataset:
Protein: MURG_CHLPD
Sequence: MNVLFAGGGTGGHLYPAVAMAGELQKRVPHVKLSFAGTEAGIEAREIPRLGYRLHLLSVRGLKRGRSLGALVDNLGVLADFIGAVRSALAIINSESPDVVVGTGGFVSAPLLLAAQMRGKKTLIQEQNAFPGVTTKLLSLFASEIHLSFEEAKPYIARKKEVYISGNPSRSFSAIDPDQARLRFGLAESLPTLLVFGGSRGARSINNAVLKWLDQITASANLIWQTGSLDYERIKAGVTSSARIWIGPYIENMGEAYAASELVVCRAGASTIAEVTNTAKPSVLVPYPHATGDHQRHNARALAENGAALLIDDEHLQAPESRQLVLDLLHDRTRRSAMSKAALLLAYPDATAALVDRIIRLAKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS13_CITBB
Sequence: MARIAGVDLPRNKRIEIALTYIYGIGRSLSQEILTAAGVDMNTRCDNLTEAEVTKIREYIDKNVKVEGDLRRDISMSIKRLMDLGCYRGLRHRKGLPCRGQRTKTNARTRKGPARTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CT2NL_PONAB
Sequence: MNLEKLSKPELLTLFSILEGELEARDLVIEALKAQHRDTFIEERYGKYNISDPLMALQRDFETLKEKNDGEKQPVCTNPLSILKVVMKQCKNMQERMLSQLAAAESRHRKVILDLEEERQRHAQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSMLVLECKKATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAKLNREENRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKKPVTVSKGTATEPLMLMSVFCQTESFPAERTHGSNIAKMTNTGLPGPATPAYSYAKTNGHCDPEIQTTRELTAGNNVENQVPPREKSVALAQEKPVENGGCPVGIETPVPMPSPLPSSGSSLSPSSTASSSLTSSPCSSPVLTKRLLGSSASSPGYQSSYQVGINQRFHAARHKFQSQADQDQQASGLQSPPSRDLSPTLIDNSAAKQLARNTVTQVLSRFTSQQGPIKPVSPNSSPFGTDYRNLANTANPRGDTSHSPTPGKVSSPLSPLSPGIKSPTIPRAERGNPPPIPPKKPGLTPSPSATTPLTKTHSQAASLTTAEDLASSCSSNTVVANGKDVELLLPTSS
What is the function of this protein?
Regulates lamellipodial actin dynamics in a CTTN-dependent manner.
What are the official names of this protein?
CTTNBP2 N-terminal-like protein.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Cytoplasm, cytoskeleton, stress fiber.
Protein: SYE_CLOAB
Sequence: MAANEIRTRFAPSPTGYMHIGNLRTALYTYLIAKHEDGKFILRIEDTDQERYVEDALAVIYKTLEMTGLKHDEGPDVGGPVGPYVQSERKGLYLDYAKKLVEKGEAYYCFCSKERLDILKTNSEALKRPFKYDKHCANLSKEEVQEKLDAGVPYVIRQNNPTTGSTTFDDVIYGRISVDNSELDDMILIKSDGYPTYNFANVVDDHLMGITHVVRGNEYLSSAPKYNRLYEAFGWNVPIYVHCPPIMKDAHSKLSKRNGDASFQDLIEKGYLKEAVLNYIALLGWNPEGTNEILSLEDMVKLFDYTHINKSPAVFDPVKLKWMNGEYVRKLSLDEFHKAALSYYDGVITKENIDLKKISELIQTRVEIFSDIPEMVDFFNELPDYDIEMYTHKKMKTNPEISLDSLKNCLPVIENIEDWNLDNIQNTIMNYIKDLGVKNGVVLWPLRTALSGKKFTPGGAFEIADIIGKDESIRRIKIGIEKLEK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PILRB_HUMAN
Sequence: MGRPLLLPLLLLLQPPAFLQPGGSTGSGPSYLYGVTQPKHLSASMGGSVEIPFSFYYPWELAIVPNVRISWRRGHFHGQSFYSTRPPSIHKDYVNRLFLNWTEGQESGFLRISNLRKEDQSVYFCRVELDTRRSGRQQLQSIKGTKLTITQAVTTTTTWRPSSTTTIAGLRVTESKGHSESWHLSLDTAIRVALAVAVLKTVILGLLCLLLLWWRRRKGSRAPSSDF
What is the function of this protein?
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system.  PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.
What are the official names of this protein?
Paired immunoglobulin-like type 2 receptor beta, Activating receptor PILR-beta, Cell surface receptor FDFACT.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NQRA_RHOBA
Sequence: MATTQSVTRIKKGLDLPITGCPEQHMEAGPAIRQVALLGDDYIGMKPTMLVSAGDRVVLGQPVFEDKKTPGVIYTAPASGTVVDVVRGAKRKFEAVVIDVDNDSTETTTIDGIAGSDPISIAREKLVDGLVQIGLWSAFRTRPFGKVPTIESRPHSIFVTAIDTNPLAADPAVVLADRKDQFVIGLQALTRLTDGAVHLCQAEKASIPGGDVAGVQSASFAGPHPAGLPGTHIHHLDPVSLNKTVWYIGYQDVIAIGSFLQTGQLDTRRVISLAGPKVNQPRLIETRLGACIDELIDGEVDTSVKLRVISGSVLNGHIATAPHQFLGRYDNQVSVIEEGDHREFLGWQKPGFDKFSVSRIFASAMTPDRKFDFTSSTGGSERAMVPLGTYEKVMPMDILATQLLRALIVRDTDSAQQLGVLELEEEDLALCTFVCPGKYEYGSLIRENLTTIEREG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: PNPB_PSEWB
Sequence: MPTKIQIVFYSSYGHIYKMAEAIAAGAREVGDVEVTLLQVPELMPEEVQVKSGIKGYRAAFGSIPYATPEVLAEADAIIFGTPTRFGNMCSQMRNFLDQTGGLWMSGGLIGKVGSVFTSTASQHGGQETTITSFHTTLLHHGMVIVGVPYSEPGLTNMTEISGGTPYGASTLAGADGSRQPSENELQIARFQGKHVATIAKRLANNK
What is the function of this protein?
Involved in the degradation of para-nitrophenol (PNP).  Catalyzes the reduction of p-benzoquinone to hydroquinone.
What are the official names of this protein?
p-benzoquinone reductase, NAD(P)H dehydrogenase (quinone).
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: VATE_THEPX
Sequence: MQGIAKIKEKIFEEATEQKNRIIEKAKKEAAEILEKARKQAVQLEAEAEKKAKKVAREEKRKILSIAELEERKRYLEAKQALINEAFVSAEKKLLNLESEKYRDLVYRMILAAAVDGNEEIIVSEADKEKITPELLERVNEALKKQGKAGNIRFSGEKRAIKGGFILKSATVEINCTFDYLLKVQREELETEVARILFEE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: RL24_CLOB1
Sequence: MSKIHVRKKDTVVVISGKDKSKIGEVLSVLPKKGKVIVKDVNVVTKHQKPNRENMQGGIIHKEAPIFSSKVMLYCDKCKSATRISNKILEDGTKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RF1_XANC5
Sequence: MTPTLRRKLEALAERREELQHLLSDPDVVGNNDTFRTLSRELSQLEPVAMALEEEARAKADLATAEALRNDPEMRELAEEEIAAAQARLEQLDAQLASLLVPRDPRDDGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDSPGEHGGYKEVVARVVGRGAYSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADDVEEITINPADLKVDTFRSSGAGGQHVNKTESAIRITHVPSGVVVECQTERSQHANRDKAMKRLKAQLLDAERSKAAAAEAQTRKLQVGSGDRSQRIRTYSFPQGRITDHRVEGLTLYDLPNIIEGDLDALIGRLLHEHQADELARLSDSP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WBNJ_ECOLX
Sequence: MSLRILDMISVIMAVHRYDKYVDISIDSILNQTYSDFELIIIANGGDCFEIAKQLKHYTELDNRVKIYTLEIGQLSFALNYAVTKCKYSIIARMDSDDVSLPLRLEKQYMYMLQNDLEMVGTGIRLINENGEFIKELKYPNHNKINKILPFKNCFAHPTLMFKKDVILKQRGYCGGFNSEDYDLWLRILNECPNIRWDNLSECLLNYRIHNKSTQKSALAYYECASYSLREFLKKRTITNFLSCLYHFCKALIK
What is the function of this protein?
Involved in the assembly of the O-repeating unit during O-antigen biosynthesis.
What are the official names of this protein?
O-antigen biosynthesis glycosyltransferase WbnJ, UDP-Gal:alpha-D-GalNAc-1,3-alpha-D-GalNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: YZ15_AQUAE
Sequence: MKERVENLLKELKERLGIEREVKIELKRFKRKLAPVSLTKRVIYINRELIPKLSDEELGYLIAHELLHLKHGIYHISEFEKELLELSGKDLYLSLYRKTWKGYNFPILQI
What are the official names of this protein?
Uncharacterized protein aq_aa15.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0123 and MJ1213.
Protein: NUSB_STRT1
Sequence: MTNIFKDSRRDLRERAFQTLFALEFGGEALDQAYFAYTYDKPIDEETEVDLPSFLLSLVTGVREELPQLDSQIEEKLKEGWSLSRLIMTDRTLLRLGLYEITSFEETPGRVAINEIIEIAKKYSDKTSAKFINGVLSQFVTDEA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AROE_VIBVY
Sequence: MTQQIDRYAVFGNPIEHSKSPFIHTLFARQTNQPLIYTAETAPKEGFVEAVKAFFAEGGKGCNVTLPFKEEAYQFASRLTERAQLAGAVNTLKKLDDGDIIGDNTDGAGLVQDLLQHQVVLAGARILVIGAGGAARGVLKPLLDQKPTSLTITNRTFSKAEELAVLFAAYGSVTAKEMNTVTEEYDVIINSTSASLSGELPALSSSIFAANSTSYDMMYGKGDTTFNQWAKQHGAAHAYDGLGMLVGQAAESFMLWRGLRPGSKQILRELRKNLEGL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NF16_NAEFO
Sequence: MITVPHVVNLNLTGQWRENGGQI
What are the official names of this protein?
Unknown protein NF016 from 2D-PAGE.
Protein: IF1A_AERPE
Sequence: MARGRGRHERRGEMPLPSEDEGTMLCIVQRVVGAGFLEVLCTDGEVYMARIPGKMRRRVWMREGDVVLFLPWGTADKKGEVVYRYLRDEVRKLIDMNLLPEELVEEVAGAE
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: Y2058_LACPL
Sequence: MASTSKPAASTTAIKKYYFYVLLCADQTLYGGFTDNLQRRLATHNAGKGAKYTRVRSRRPLQLIYHETFTDKSSALKAEYAFKHQSRAAKLKYLSAHDVKI
What are the official names of this protein?
UPF0213 protein lp_2058.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RPO1H_MIMIV
Sequence: MGFNKEDRILINNNNSRISRGISERYKGKEGRIRSNMMGKRHDVKSLLEYLDSTCIPIENMLCNDDESSIKPQSKYHRQKKFRNNFSSQNKFHHQKIFPRQKFSKFHR
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit 1 inactive homolog.
Protein: RNA14_ASPFU
Sequence: MAEEDAEKAFFQAQTMNAESVDYKAVEEHGADSSDSDDYDPSKTLQDQYSSSMTDLKQSENVSSSASPEPNPTEQNSVQPDHDPSQPDGASYPSQTPPRDESRTSTMVPTSGTSVQPKTRTIGGFVVEDEDEDDAGDADYEPPAVLGVEDMNTVATNVPQQSVSGNENEASSTPDVSLDDAAQQSASLNNVSHNSYSPAPAVAPKSDVAVAAGQSLYNSHALQSGNVQDSATATPTPDSPSTSKGRLPHDRVGILEDRIQEDPRGDIPAWLELINEHRSRNRFDSARDVFERFLKVFPFAAEQWVAYAKMESELNDLYRLEQIFNRTLLTIPDVQLWSVYLDYVRRRNPLTTDTTGQARRIISSAYELAFQHIGVDKDSGSIWSDYVQFIKSGPGNVGGSGWQDQQKMDLLRKAYQKAICVPTQAVNTLWKEYDQFEMGLNKLTGRKFLQEQSPAYMTARSSYTELQNITRDLIRTTLPRLPPVPGSDGDIEFTQQVDIWKRWIKWEKGDPLVLKEEDPAAFKGRVVYVYKQALMALRFLPEMWFDAAEFCFLNDLESEGNEFLKQGMEANPESCLLAFKRADRLEITSESEQDPIKRGAKVREPYDKLLDALYDLIAKARTREAQDVARLEETFAKMNADNPPAKTDDDDDDQSESKARESVKNAQIDAVRKAHAIQIGILSKTISFAWIALMRAMRRIQGKGKPGETPGSRQVFADARKRGRITSDVYIASALIEYHCYKDPAATKIFERGAKLFPDDENFALEYLKHLIDINDIINARAVFEMTVRKLASNPDNVHKTKPIFAFLHEYESRYGDLVQVINLENRMRELFPEDPTLEQFAHRYSAPTFDPTAVRPIISPSQMRPKAVFPTSEQPMSRHGTPTPRYPGSVTDSPKRPLEDFDDDYNRPRKFVRAESPLKTSQRRQLDQQKRSQLSNVQTGSQFRSQGSPAPLPRDIVHLLSIIPPASAYTAGRFSPEKLVDLIRRIEMPSSISQIPLPQSARGLGTTQTPMQPFSGKASPSLSVRAVY
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA 3'-end-processing protein rna14.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Protein: TNR3_SCHPO
Sequence: MAMSSITSAKQLNAEELLDECDSFNGEFVPGTIPFRANGAAIGYVTPLVLEILIKADNFKFNWVYVPGEYIEINASTFEKRTDILAKVLEHWRHNNTFGIADQWRNELYTVYGKSKKPVLAVERGGFWLFGFLSTGVHCTMYIPATKEHPLRIWVPRRSPTKQTWPNYLDNSVAGGIAHGDSVIGTMIKEFSEEANLDVSSMNLIPCGTVSYIKMEKRHWIQPELQYVFDLPVDDLVIPRINDGEVAGFSLLPLNQVLHELELKSFKPNCALVLLDFLIRHGIITPQHPQYLQTLERIHRPLPVPVGKYERGDSFEDTSKKAETCVPAKPQKATHQLAPCKAWLRDYDTDQKFAVLLLNQPIDIPDDRFRTLWKRASIRVCADGGANQLRNYDSSLKPDYVVGDFDSLTDETKAYYKEMGVNIVFDPCQNTTDFMKCHKIIKEHGIDTIFVLCGMGGRVDHAIGNLNHLFWAASISEKNEVFLLTELNVSTLLQPGINHVDCHDNIGLHCGLLPVGQSVYVKKTSGLEWNIEDRICQFGGLVSSCNVVTKATVTIEVNNFIVWTMETRL
What is the function of this protein?
Involved in the regulation of thiamine metabolism, phosphate metabolism, mating and cell growth.
What are the official names of this protein?
Thiamine pyrophosphokinase, TPK, Thiamine kinase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_PROM0
Sequence: MAKDALIVKTTPLPQSRISFELEIPSETCKTCVNETISTISRSAKIPGFRLGKIPKQVLIQRIGITQLHASALEKIIDKSWQEALKIKSIEPLSEPELVDGFESLLAKFSPEKSLKVTLQTDVAPELKLKKSKGLSVEISKTKFDPKSIDEALEKSRNQFANIIPVTNRAAKLGDIAVVSFKGKYKDSGKEIDGGTSESMDLELEKNKMIPGFVEGIVKMKIGDTKTLNLKFPEDYSHEDSRGKEAIFEVNLKDLKEKELPELNDDFAKQSGNKESLKELKKDIEKQLKDNFEKTQKDIKIEALLDALTNELVTEIPKSMIDLEVRNNIEQTAQRFAQQGLDVKSTFTPELVKSLAESTRPQAEKNVQRNLALKALAEKENITIDKSEIDLKMKEYDDVISQSSKQIDIKKLTEVISNDLLKEKLIIWLEENSEVNEKTTKTSKATKTSKTTKATKTATKTTKTTKTTKTQNKKEKK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: KCRS_RABIT
Sequence: MASTFSKLLTGRNASLLFATLGTSALTTGYLVNRQKVCAEARDQHKLFPPSADYPDLRKHNNCMAECLTPSIYAKLRNKVTANGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHPTDLDASKITQGQFDERYVLSSRVRTGRSIRGLSLPPACSRAEAREVENVAITALEGLKGDLAGRYYRLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDNTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTRAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity).
What are the official names of this protein?
Creatine kinase S-type, mitochondrial, Basic-type mitochondrial creatine kinase, Mib-CK, RSMTCK, Sarcomeric mitochondrial creatine kinase, S-MtCK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: SYP_PSELT
Sequence: MKFSQLYAPTLKEAPADAEVISHALLYRAGFIRKIAAGVYSYLPLAKRTLSKIEAIVRKEMNEIGAQEVSMPVIQPAELWKTTGRWDDYGPEMMKLKDRHERDFTLGPTHEEVFTHMVKDELRSYKQLPLFLYQIGPKYRDEIRPRFGLLRAREFIMKDGYSFHDSDQSLNETYEACKNAYRKITEKIGLKYIIIEAASGAIGGNESHEFVSFAPVGETNLLKCEKCGYSSNDEQAPYRGKYHRDEEIEKPVELIHTPNVRSVEQVAEFLNVSKNKIVKSLLFIGRNGFVMALIQGDRELNIEKLKVHVNDQSLRLAEPDEVLQAFRVPIGFIGPVGIEKVHVVADCGIKYMKNVVVGGMKKDYHYINANVGRDFSPDSYTDLRVVQPNDPCPVCGEQLTGSKGIEIAQIFKLGTKYSKAMNALYMDDKGEVKPFIMGCYGWGISRTMAAIVEQLHDEDGILWPRSVAPFELIITVVSAQDQDQRIFAQKLYNSLLSSEIDVLLDDRDISPGMKFKDADLIGFPLRITVGKSLKEGMVELKSRNSSKSIKVSAELSKINSVLFKMLEEYNPHERV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RICBR
Sequence: MQKGAKNRLITIIICFCSAVIGVSIILYNLEKSIVFFVPPSKINEVEQGKELRVGGLVKVDSINKIAADKISFVITDNIKDLEIFYQGVLPALFRENQGIIAIGRLSNGKFIARELLAKHDENYRPPNTVIPAKAGI
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: OTC_YERPP
Sequence: MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPGGSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLAYLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEPKEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENRLHTIKAVMVATMSKI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLD20_HUMAN
Sequence: MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFCTSCIKRNPEARLDPPTQQPISNTQLENNSTHNLKDYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-20.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: NS1_I57A0
Sequence: MDPNTVSSFQVDCFLWHVRKQVADQELGDAPFLDRLRRDQKSLRRRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSKVRRNKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: TSAD_PROMP
Sequence: MHKVLAIETSCDETSVSIVSNSGDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELLPFVLEQALEESKIRIEKIDVIASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKVGERRKMQRLGRSYDDAAGEAFDKVGRLLGLSYPGGPAIAKIAKKGNASKFNLPKCKISDKEGGFLKYDFSFSGLKTAVLRLVEKINLNGDEIPIPDIAASFERVVAEVLVERTIKCANDYGLDNIVVVGGVAANDTLRKMMISEACKKSIKVHLAPINLCTDNAAMIGAAALYRLKFKAYESSLKLGISGRLPIDQANTLYENKPPF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SART_STAA8
Sequence: MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
What is the function of this protein?
Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes.  Represses alpha-hemolysin (hla) gene expression.  Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression.  Up-regulates sarS, which induces the expression of the cell wall-associated protein A (spa).
What are the official names of this protein?
HTH-type transcriptional regulator SarT, Staphylococcal accessory regulator T.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.