PharMolix/UniProtQA huggingface dataset:
Protein: AUR51_RANAE
Sequence: GLLDIVTGLLGNLIVDVLKPKTPAS
What is the function of this protein?
Has no antimicrobial or anticancer activity.
What are the official names of this protein?
Aurein-5.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_MYCPA
Sequence: MKSGIHPDYHPVVFQDATTGATFLTRSTITSSRTIEWETPHGVRTYPLVVVEITSDSHPFWTGSRRIVDTAGQVEKFHRRYGSRRQTNHRDDAAHSP
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: SYQ_BORPE
Sequence: MTHAPTPPAASNFLRPIIEDDLQANRFQGKLWAGKPGPAALQAQGQPDPARIRTRFPPEPNGYLHIGHAKSICVNFGLARDYGGVCHLRFDDTNPEKEEQEYVDAIIEAVHWLGFDWQADGNDNLYFASDYFEFMYEFAEALVQAGHAYVDEQSAEEIRASRGTLTEPGTDSPWRDRPADESLLRLREMRDGKHPDGSLVLRARIDMASPNINLRDPVMYRVRHATHHRTGNAWCIYPMYSWAHPVEDALEGITHSICTLEFEDQRPFYDWILARLAELGKLARPLPHQYEFARLNLTYVVTSKRKLLQLVREGYVDGWDDPRMPTLFGLRRRGYTPSSIRLFCDRTAVSKSDSRIDYSLLEQAVRDDLDPVAPRSVAVLDPLKLVITNYPEGRSETCSAPRNPHDPQAGVREFPFTRELWIEQDDFREEPPKKYFRLFPGNTVRLKYGYVVRCTGFTKDESGKVVEVQAEYLPDTKSGTPGADSVKVKGNITWVSAAHAVPAQVHLYDRLFADAHPDGGDKDFLACLNPNSKQTVQAWLEPGIEAVPGATWQFERLGYFTVDSKDSRPEAPVLNRIVTLRDSWQAA
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_HHV6Z
Sequence: MALLQWMLDHVQDEEKNYENLSIDDQHSLFGINRDWLSFLQLSKLEITHLKHVYKLVDNDRVHLTVHPSSDNVHAWSFLCKPTDVKVVILGQDPYPDGRGCGLAFGTVKECSIPESLKNIFKELERSIPNFSPPDNGCLNSWCREGVLLLNSIFTVVHGLPMSHEAFGWQTLSYKIISRLSEQMNSLVFLLWGKHARKLSYLIDAQKHLVLESAHPSPKVKSARMPFIGCNHFVRTNLFLTEHGKDPINWNILNE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL14_SALRD
Sequence: MIQQETRLNVADNSGAKEAQCIRVLGSSGRRYAGIGDQIVVSVKSAIPSGEINKGDVSRAVVVRTAKETRREDGTYIRFDENAAVLINQEEEPVGTRVFGPVAREVREKQFMRIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YRA2_YEASV
Sequence: MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSDAASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDRTCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEQGRGRPGSHYRQRPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: POP7_YEAST
Sequence: MALKKNTHNKSTKRVTKHPSLKTLTHKQIHTTIFVKSTTPYVSALKRINKFLDSVHKQGSSYVAVLGMGKAVEKTLALGCHFQDQKNKKIEVYTKTIEVLDEVITEGQADIDMESDVEDDDKETQLKKRAVSGVELRIYV
What is the function of this protein?
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of RNase MRP, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonucleases P/MRP protein subunit POP7, RNA-processing protein POP7, RNases P/MRP 15.8 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
Protein: RPOC_AQUPY
Sequence: MSTKGRGIFPFSKIKLMLASPDDIRSWSHGEVKRPETLNYRTLKPEKDGLFCAKIFGPTKDYECLCGKYRGKRYEGKICEKCGVEVTSSYVRRERFGHIELAAPVVHIWFLKSTPSKIGTLLNLTSRDVERVAYFESYLVIEYPNEEEEEKFEKEEGTIPLNDGISTKWVKLHVVNEEEFEEKYAFSIDEKYEYGMGAEILKEVLSKIDLEAYSKKLKELVKPYSLGFEDLGREVAEKYKNLYQKLVKVIADDFRAYGVELKGLEDKGLTLEQAIHRIITEELYLNVETGEVEFEDCGDNCLTGREALRVYYEKVREHKRDIPIFEKIKEDVRTAVLREVSEARIRKALRILQLVEGFKKSGNRPEWMILEVLPVIPPELRPLVALDGGRFATSDLNDLYRRVINRNNRLKRLIELSAPDIIIRNEKRMLQEAVDALIDNGKRGNPVKQNGRPLKSLADYLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELQMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKHAKKLVEQKTPEVWECLEEVVKQHPVLLNRAPTLHRPSIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPLGIEAQLESYILMLSTQNILSPAHGKPLTMPSQDMVLGTYYMTHDPIPGRKGEGKAFTSYEEVIKALELGHVDIHAKIKFKVGKEWIETTPGRVLFNSIMPEGQPFVNETLDKKRLSKLITNLYIAVGNEETVKFLDRVKELGFLRSTLAGISIGIDDLQVPKVKEKIIKEALKKTEEIWNQYVQGIITNKERYNRIIDVWSEATNAVSKAMFEEIEHSTEIRNGKEYPGTFNPIYMMAVSGARGNRDQIRQLAGMRGLMAKHSGEFIETPIISNFREGLSVLEYFISTYGARKGLADTALKTAFAGYLTRRLVDVAQDITITEKDCGTVKGFEMEPIVEAGEERVPLKDRIFGRVLAEDVKDPYTGEVIAKRNEVVDEKLAERIARAGIEKVKVRSPLTCEAKHGVCAMCYGWDLSQRKIVSVGEAVGIIAAQSIGEPGTQLTMRTFHIGGAATAQKVQSFVKTESEGTVKFYNVKFIVNRKGEKINVSKDAAIGVLDEKGRLLERHTIPYGARLLVDEGQKVKAGTKLADWDPFNTYIIAEVGGKIELRDIILDVTVREERDVITGKTATVVSFMRPKDAMLHTPRIAVITEDGKEYVYDLPVNAILNIPADKLTLEWRICPTCSESEETTIQHQYYVVKELEVQPGDILARIPKETAKVRDIVGGLPRVEELFEARKPKNPAILSEIDGYVKIYEDADEVIVFNPRTGETKKYAIKKDELILVRHGQYIKKGQKITETKVAEIDGQVRIKGRGFKVIVYNPETGLQREYFVPKGKFLLVKEGDYVKAGDPLTDGTPVPEEILRIKGIEELEKFLLKEVQMVYKLQGVDINDKHFEIIIRQMLKKVRIIDPGDSRFLVGEEVDKEELEEEIQRIKLEGGKLPKAEPVLVGITRAALSTRSWISAASFQETTRVLTDASVEGKIDELRGLKENVIIGNLIPAGTGVDEYKEVDVIPAEEKVLEEKPQSSEEETS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BIOB_SALPK
Sequence: MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWKNPHERDMPYLEQIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL16_MAGSA
Sequence: MLSPKRTKFRKAHKGRIKGVTKGGSALNFGAYGLKALEPERITARQIEAARRALTRHMKRQGRVWIRIFPDLPVSSKPAEVRMGSGKGAPEFWTARVAPGRILFEVDGVAEEIARHGFALAAAKLPIKTKFISRIGDI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS17_LACE2
Sequence: MEERNLRKTRTGKVISNKMDKTIVVAVQDNVKHPLYNKIVKRTYKLKAHDENNECLIGDVVKVMETRPLSKDKRWRLVEIISRAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CYB6_PROMT
Sequence: MANSSPVYDWFQERLEIQDIADDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVTEAYSSVSYLMTDVSFGWLIRSVHRWSASMMVLMLILHVFRVYLTGGFKRPRELTWITGVVMAVITVAFGVTGYSLPWDQVGYWAVKIVSGVPAAIPVIGDFMVELLRGGESVGQSTLTRFYSLHTFVMPWLLAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: TOP3A_OXYTA
Sequence: GIKDYLKKLLQKAINKIKSLRKKQDA
What is the function of this protein?
May have cytolytic and antimicrobial activity.
What are the official names of this protein?
Oxyopinin-3a, Oxt-3a.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGD_STRAW
Sequence: MTGTATNAELTERWQGALMNNYGTPRLPLVRGAGTRLWDADGKEYLDFVGGIAVNALGHAHPAIVEAVSTQIASLGHVSNLFVAEPPVALAERLLQLFGRDGRVYFCNSGAEANEAAFKIGRLTGRSHMVATQGGFHGRTMGALALTGQPGKQEPFLPLPGDVTHVPYGDAQALAAAVTEETALVVIEPIQGENGVVVPPAGYLKAARAITAATGSLLVLDEVQTGIGRTGHWFEYQAHEGVLPDVVTLAKGLGGGLPLGATVAFGRAAELLQPGHHGTTFGGNPIACAAGLAVLETIQAEGLLENVKSASEKLRDGIESLGHPLIAHVRGSGLLLGIVLTEPLAPQAQQAAQDAGFLVNAPAPDVVRLMPPLNLGDDEVDAFLRALPGVLDAVTNGDGRAKE
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM2_EHV1B
Sequence: MYGRSNAPGCQPPVRAHPPSSPMTSRLQLAAMEQNASDAALSGMQQARSRQASPKRLRDLIPSSDVESMSLNALDDAYGHHDFSVWFEDLMPPEMELLMPTTDAKLNYLSFTRRLASSVFHSPDNRMPGGACDHTSALDARKERFATIINKFLDLHQILHDA
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: YT72_CAEEL
Sequence: MDDKELFPKVDILNLTFSPKSEISEDVFKQMFSSLDRLWWSRLVISIRGYVINYVQQNDEVLFSCDDAFIKIHQKLAERNSQFEDAFEYLTAIFHVIREKNTLIQMISNPKSISTTKISPNLDRSFNIIHGNLTPKTIQLTIAQLPAYTMFIKVVVNLQQRWENEKLKKKSIRFETDPEWEPDERVVLFQTFASGMTSRIRYDK
What are the official names of this protein?
Uncharacterized protein C01C10.2.
Protein: Y4916_RHIL3
Sequence: MLYYALVFLVVALIAGVLGFGGIAGASASIAQVLFFIFLVLFVVSLVMRLMRKV
What are the official names of this protein?
UPF0391 membrane protein pRL90066.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KCNKI_RAT
Sequence: MEAEEPPEARRRCPEALGKASGCCPEAPGKARGCCPEALGKLLPGLCFLCCLVTYALVGAALFSAVEGRPDPEAEENPELKKFLDKLCNILKCNLTVVEGSRKDLCEHLQQLKPQWFKAPEDWSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYALFGIPLMFLVLTDIGDILAAILSRAYSRFQALLCLPRDISKWRPLLLCRKQTDSKPADEAIPQIVIDAGADELLDPQPSREPASPSCNVELFERLVAREKQNELQPPMRPVERSNSCPELVLGRLSCSILSNLDEVGQQVERLDIPLPVIALVIFAYISCAAAILPFWETDLGFEDAFYFCFVTLTTIGFGDIVLVHPHFFLFFSIYIIVGMEILFIAFKLMQNRLLHTYKTLMLFVCQREVSLPC
What is the function of this protein?
Outward rectifying potassium channel.  Produces rapidly activating outward rectifier K(+) currents.  May function as background potassium channel that sets the resting membrane potential.  Channel activity is directly activated by calcium signal.  Activated by the G(q)-protein coupled receptor pathway.  The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation.  Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids.  Channel activity is also enhanced by volatile anesthetics, such as isoflurane.  Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper.  May be involved in the somatosensory function with special respect to pain sensation (By similarity).
What are the official names of this protein?
Potassium channel subfamily K member 18, Tresk-2, Two-pore-domain potassium channel TRESK.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBA1_ARATH
Sequence: MSSINLSSSSPSTISLSRSRLSQSSTTLLHGLHRVTLPSNHPLSTFSIKTNTGKVKAAVISREDDLLSFTNGNTPLSNGSLIDDRTEEPLEADSVSLGTLAADSAPAPANGFVAEDDDFELDLPTPGFSSIPEAIEDIRQGKLVVVVDDEDRENEGDLVMAAQLATPEAMAFIVRHGTGIVCVSMKEDDLERLHLPLMVNQKENEEKLSTAFTVTVDAKHGTTTGVSARDRATTILSLASRDSKPEDFNRPGHIFPLKYREGGVLKRAGHTEASVDLTVLAGLDPVGVLCEIVDDDGSMARLPKLREFAAENNLKVVSIADLIRYRRKRDKLVERASAARIPTMWGPFTAYCYRSILDGIEHIAMVKGEIGDGQDILVRVHSECLTGDIFGSARCDCGNQLALSMQQIEATGRGVLVYLRGHEGRGIGLGHKLRAYNLQDAGRDTVEANEELGLPVDSREYGIGAQIIRDLGVRTMKLMTNNPAKYVGLKGYGLAIVGRVPLLSLITKENKRYLETKRTKMGHMYGLKFKGDVVEKIESESES
What is the function of this protein?
Involved in riboflavin biosynthesis.  Catalyzes both the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate and the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.  RIBA2 and RIBA3 together are not able to complement the loss of function of RIBA1.
What are the official names of this protein?
Bifunctional riboflavin biosynthesis protein RIBA 1, chloroplastic, AtRIBA1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_CLOPS
Sequence: MVHPVQVGKRTRMSFAKVKDVAEMPNLIEIQLDSYKWFLDAGLYEVFDDINPISNFTGNLVLEFVGYTLDMDNIKYSVEECKERDTTYAAPLKVAVRLQNKETGEIKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNYNVDKTGKKLFSATVIPNRGAWLEYETDSNDVIYVRIDKTRKLPISILGRAMGFGSDQELLEYFGEEERFKATIEKDNTKTKEEALLEIYKRLRPGEPPTVDSAISLIDSLFFDAKRYDLSRVGRYKFNKKLAIGLRIANQIAAEDIVDKLTGEVLVAKGEKISRANAEEIQNRGINSVDVLVEDRVIRIIGNHFVDIHKCVDFDISDLNIRELVHYPTLREILDNYSDEETIKEEIKKNMTRLIPKHIIKDDIFATISYQIGLAYNIGYVDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEAITPQQLINIRPVAAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYAKVNEYGFIETPYRVVDKSEGRVTGEIRYFTADEEDQYLVAQANEPLDENGCFIDKKVTVRDKGEVLVVPSKDVDLMDVSPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVPLLKPYAPIVGTGIEYKAAVDSGVLPKAKNAGEVVYVSANEVRVKRELDGGVDTYRLLKFKRSNQGTCINQRPIVAKGDWVLKGEVLADGPSTDLGEIALGKNIRMGFITWEGYNYEDAMLISEELVREDVFTSIHIEEYECEARDTKLGPEEITRDIPNVSEDALKDIDERGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDVKVFTRENGDDLSPGVNELVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASALGWHIATPVFDGATETDIEDCLEKAGYNRNGKTVLRDGRTGEEFDNEVTVGIMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDVKVLNDNNQEVKFKELAEDDDEIEVLEVNMEGTEDSTTEEAKEEKGEAYIPAEEIDEEIDYENIDLLDFTSDLDIEDDFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RR14_ILLOL
Sequence: MARKSLIQRERKRDKLEQKYHLIRRSSKKQISKVPSLSDKWEIHGKLQSPPRNSAPIRLHRRCFLTGRPRANYRDFGLSGHVLREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLMM_PSYIN
Sequence: MKKKYFGTDGIRGKVGASLITPEFTLKLGWAAGRVLAKSGSKKVLIGKDPRISGYMLEAALEAGLAAAGLRPVLMGPMPTPAVAYLTQTFRATAGIVISASHNPYYDNGIKFFSDQGTKLSEEIELEIEAEIDKELKCVDSSELGKAYRIEDAAGRYIEFCKSTFPSKYNLNGLKVVVDCANGATYHIAPLVISELGADVIAMGVEPDGLNINLNCGATSMQAISERVVKENADFGIAFDGDGDRVMMVDHTGYVLDGDELLYIIARDKLRSGTLKGGAVGTKMSNLGLEQSLKTLGIPFERSDVGDRHVMELMIKNNWCIGAENSGHIICSDHLSTGDGIVSGLQVISAMQSSRMKLYELRQGIKKYPQILLNLGFDNKIDPLQDNDVLAEAKRIETLLGDKGRVLLRKSGTEPVFRIMVEADESEKVVRGYAKSIADKVKV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CERS3_HUMAN
Sequence: MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
What is the function of this protein?
Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very- and ultra-long-chain fatty acyl-CoA (chain length greater than C22) (PubMed:17977534, PubMed:22038835, PubMed:26887952).  N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively (PubMed:17977534, PubMed:22038835, PubMed:26887952).  It is crucial for the synthesis of ultra-long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation (PubMed:23754960).
What are the official names of this protein?
Ceramide synthase 3, CerS3, Dihydroceramide synthase 3, LAG1 longevity assurance homolog 3, Sphingosine N-acyltransferase CERS3, Ultra-long-chain ceramide synthase CERS3, Very-long-chain ceramide synthase CERS3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATP18_YEAST
Sequence: MLKRFPTPILKVYWPFFVAGAAVYYGMSKAADLSSNTKEFINDPRNPRFAKGGKFVEVD
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit J, mitochondrial, ATPase synthase I subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase j subunit family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HIS8_CITBB
Sequence: MIALRENIAEMAGYVPGFQPLDVDSYIKLNTNENPYPPSPKVLEAIAKEAGEGLRRYPDAASRLAREEAAKVYGFDPSWIIMANGSDEVLNNLIRACAGEGEEIAFINPSYSYYGTLAEVQGARVRTFGLSESFEPEGIPEHYDGKLFFLTNPNAPLGFTYSQRYIADLAGRLSGVLVVDEAYVDFAEETSLELVRSFDNVVVTRTFSKSYSLAGMRLGLAIARPEIIAALNKIRDHYNLDRLAQAAAAAALADQPYFQECVRKIKETRAWFTAELQQLGYQVIPSSGNFVFASPPDRDGTRIYQGLYDRKILVRHFTDPKLAHGLRISIGSREEMEQTVKALRELGPGR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SPB4_NEOFI
Sequence: MAPKPPSGTSSRAWDAVTPALSEWVLEAMSSMGFTRMTPVQASAIPLFMAHKDVVVEAVTGSGKTLSFLIPVVEKLLRLEEPIKKHHIGAIIISPTRELASQIYNVLSSLLAFHPPSAAAINPSEDDDAPRPKFPSSTLKVVPQLLLGGSTTPAEDLSTFLKRSPNVLVSTPGRLLELLSSPHVHCPQSSFEMLVLDEADRLLDLGFKETLQNILRRLPKQRRTGLFSASVSEAVDQIVRVGLRNPVKVMVKVKGGSGVDDKRTPASLQMTYLTTPPSHKFAALKRILSSVQPTPLKTIFFVSTCSGVDYLSAILPLLLGDDFLLIPLHGKHQANVRQKNFNRFINSHDPAILLTTDVAARGLDIPSVDLVVQIDPPSDPKSFIHRCGRAGRAGRRGLSVVLLHPGREEDYVSFLEVRKTPVVPFSPLITFSDADAAAATATARKAVLADRALHDRGQKAFVSWFRSYSKHQASSIFRVSDLDWEALGKAWGLLKLPKMPELRNFTGDKTLGVSLDWNNYAYKDKQREKRRKELLQEAAESGATQSTSNKRRATESVAWSQQAESKNKKLKRREQKKSKHEKARWEKMTEEEKQKVLETEKMVEELRKKNEEERRLRRAAAKAAGAKADGDDEEEFQGFD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase spb4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LEPA_GLOC7
Sequence: MTDVPVSRIRNFSIIAHIDHGKSTLADRMLQMTGTVEDRKMKEQFLDNLDLERERGITIKLQAARMNYTAQDGQHYVLNLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTLANVYLALENNLEIIPVLNKIDLPGAEPERVAQEIEEIVGLDCSGIIKASAKEGIGVNEILESIVHLVPPPDDTTNKPLRALIFDSYYDSYRGVVVYFRVMDGTVKKGDRVLLMASGKEYEIDELGVLSPHQIQVDELHAGEVGYFAAAIKTVEDARVGDTITLAPKPADEPLPGYKEAKPMVFCGLFPTDSDQYEDLRDALHKLKLNDAALNFEPETSTAMGFGFRCGFLGLLHMEIVQERLEREYDLDLITTAPSVVYRVTTTEEEVIEVDNPSQLPPPQKRIKIEEPYVHMEMITPETYVGALMELCQNRRGEFKDMRYFTQTRTALVYELPLAEIVTDFFDQLKSRTRGYASMEYHLIGYRENALVKLDIMVNGDGVDALAMIVHRDKAYNVGRALTEKLKELIPRHQFKVPIQAAIGSKVIASEHIPALRKDVLAKCYGGDITRKKKLLEKQAKGKKRMKSIGTVDVPQEAFMAVLRLNNES
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.