PharMolix/UniProtQA huggingface dataset:
Protein: OPGC_SALEP
Sequence: MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFQKRQETSKPRPAAISLVRLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_XANOM
Sequence: MTDCSRCAGTNASGPNHWSERIRDIVDFPKPGIVFKDITPLLSDGPDFASALDEMAQPWRTTPLDAVLGIEALGFILGAALARELRTGFVPVRKPGKLPGRTLIREYALEYGTDRIEMHEGALPRGARVLIVDDVLATGGTLRAALGLAAQLELEIVGAAVLVELLALQGRQKWADDVPLLATLSF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2656_MYCTO
Sequence: MTAVGGSPPTRRCPATEDRAPATVATPSSTDPTASRAVSWWSVHEYVAPTLAAAVEWPMAGTPAWCDLDDTDPVKWAAICDAARHWALRVETCQAASAEASRDVSAAADWPAVSREIQRRRDAYIRRVVV
What are the official names of this protein?
Uncharacterized protein MT2733.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1583c.
Protein: SQE2_PANGI
Sequence: MELERSYRENDEYFLMFAATLLFGFVLYLFTLRRRRRRREKKGGAGSMEIINGAYKMTSSSEVNGHCTPEDIAGSSDDVIIVGAGVAGSALAYTLAKDGRRVHVIERDLTEQDRIVGELLQPGGYLKLVELGLEDCVNEIDAQRVFGYALYMDGKNTRLSYPLEKFHADVAGRSFHNGRFIQRMREKAASLPNVRMEQGTVTSLVEQKGTVKGVRYKTKNGQEMSAAYAPLTIVCDGCFSNLRHSLCNPKVDVPSCFVGLILENIDLPHINHGHVILADPSPILFYKISSTEIRCLVDVPGQKVPSIANGELAHYLKTSVAPQIPPELYKSFIAAIDKGKIKTMPNRSMPADPHSTPGALLLGDAFNMRHPLTGGGMTVALSDIVLIRDLLRPLRDLHDSSTLCKYLESFYTLRKPVASTINTLAGALYKVFCASPDKARQEMRDACFDYLSLGGICSEGPIALLSGLNPRPMSLFFHFFAVAIYGVGRLLIPFPSPRKMWLGARLISGASGIIFPIIKSEGVRQMFFPATVPAYYRAPPITKKM
What is the function of this protein?
Component of the triterpene saponins (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:19857882, PubMed:29378087).  Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway (By similarity).
What are the official names of this protein?
Squalene monooxygenase SE2, Squalene epoxidase 2, PgSQE2, SE2.
What is the protein family that this protein belongs to?
Belongs to the squalene monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RBL_MORRU
Sequence: VGFKAGVKDYKLTYYTPEYEVKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAVEGNEIIREASKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MRAY_PSEE4
Sequence: MLLLLAEYLQQFHKGFAVFQYLTLRGILGVLTALSLALWLGPWMIRTLQIRQIGQAVRNDGPQSHLSKSGTPTMGGALILSAIAISTLLWADLTNRYVWVVLIVTLAFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLAAAIFLYKTAPTSVETTLIIPMLKDLAIPLGAGFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGAGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEVVLFIMGGVFVMETLSVVIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YAJQ_ECO27
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAVVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: GP176_MOUSE
Sequence: MGHNSSWVSPNTSHPRNTSGAEAGANLSAFGELSEAQLYRQFTTTVQVVIFIGSLLGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASVVCVPFDIILSSSPHCCWWIYTMLFCKVLKFLHKVFCSVTVLSFPAIALDRYYSVLYPLERKISDAKSRELVMYIWAHAVVASVPVFAVTNVADIYAMSTCTEVWSNSLGHLVYVLIYNVTTVIVPVAVVFLFLILIRRALSASQKKKVIIAALRTPQNTISIPYASQREAELHATLLSMVTVFILCSVPYATLVVYQTVLNVPNTSVFLLLTAIWLPKVSLLANPVLFLTVNKSVRKCLVGTLVQLHHRYSRRNVVSTGSGVAEPSLEPSMRSGSQLLEMFHIGQQQIFKPSEDEEESEAKYLGSADFQAKEVLTSCPEGEQEPPQLAPSVPPPGTVDSEPRVSPVAPMESGIFPDKYSLQFGFGPFELPPQWLSETRNSKKRLLPPLGNTPEELIQTKVPRVNRVERKMSRNNKVSIFPKVDS
What is the function of this protein?
Orphan receptor involved in normal circadian rhythm behavior (PubMed:26882873).  Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production (PubMed:26882873).
What are the official names of this protein?
G-protein coupled receptor 176, G-protein coupled receptor AGR9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSG_CHLPN
Sequence: MYKWYVVQVFTAQEKKVKKALEDFKESSGMTDFIQEIILPIENVMEVKKGEHKVVEKYIWPGYLLVKMHLTDESWLYVKSTAGIVEFLGGGVPVALSEDEVRSILTDIEEKKSGVVQKHQFEVGSRVKINDGVFVNFIGTVSEVFHDKGRLSVMVSIFGRETRVDDLEFWQVEEVAPGQESE
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: NRNA_MYCGE
Sequence: MKKGSITEAINAIKQFDKIVIFHHVRPDGDCLGAQQGLFHLIKANFKNKEVKCVGNNNNLFSFINMTFTNQIDESFLKEALAIVVDANYKNRIELRELLDKNLFKAVLRIDHHPNEDDLNTSFNFVEESYVACCEQIVEMATVAKWTIPPVAATLLYIGIYTDSNRFLYSNTSYRTLYLAAILYKAKADIRIVHDHLNHTSLADLKFKKYVYNHFKTQGQVIYFICTKKIQKRLRMTADQCARVNLLSNIADYKIWLFFIEQANNEIRIELRSNGINVRDIAIKYGGGGHNNASGAIITNKKQISDVVSDCVKKIVYN
What is the function of this protein?
Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities.  Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for longer oligomers.  Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP (By similarity).
What are the official names of this protein?
Bifunctional oligoribonuclease and PAP phosphatase NrnA, 3'(2'),5'-bisphosphate nucleotidase, 3'-phosphoadenosine 5'-phosphate phosphatase, PAP phosphatase, Mgp-operon protein 1, Mgp1, ORF-1 protein, nanoRNase.
What is the protein family that this protein belongs to?
Belongs to the NrnA oligoribonuclease family.
Protein: PED1B_MOUSE
Sequence: MVRLLASEVQQLLHNKFVVVLGDSVHRAVYKDLVLLLQKDCLLTNKQLRTKGELSFEKDQLKMGGELDTLHNRTDYREVREFCSDHHLVRFYFLTRVYSEYMESVLEELQSGNHAPDVIIMNSCLWDVSRYGRNSLSSYKQNLENLFGRMDQVLPKSCLLVWNTAMPLGDKIKAAFLPQKCKGQYPRISVATLKRKVTQANLYSHAEATKHYFDVLDLNFHFRQARKHLQGDGVHWNEHAHRKLSYLLLAHMADAWGVELPQRDSWEPDFEAWESSGQVEERQPQDNLGPQVFAPSPHCPFRPPPLLPSPGLPIRPPPLLGCPLPQPQQMPPFPLYPQVSYFSSDPVFQSDEFYIHSDSPPPTHTGYAFEGDFSFYPQPPVPNFRPPCHQRQAPVVHRGFPRHFARGPYSNPWRDRPRRPPKHSPAGLESRPQ
What are the official names of this protein?
PC-esterase domain-containing protein 1B, Protein FAM113B.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family.
Protein: ILVD_LEPIN
Sequence: MGDNLKKRSSMTTDGDNRAPNRAMLRAVGFTDEDFHKPMIGIASTWSEITPCNIHINKLAEKVKEGVREAGGVPQIYGTITVSDGIMMGHEGMHFSLPSREVIADSIEIVSNAMRHDGVIAIGGCDKNMPGCLMALCRIDAPSIFVYGGTILPGNCDGQDVDIVSIFEAVGKFNAGKISREEFIRIEQNAIPGAGSCGGMYTANTMSSAIEALGMSLPGSASMPAVSSRKANDCYEAGKALINLIQKGITPKQILTKKAFENAITVVLVLGGSTNAVLHLIAIAKEIGVGLTLDDFDRISKKTPHLADLKPGGKYAMTDLDKVGGVHGVMKYLLKEGMLHGDCLTVTGKTIAENLKDMPDLVPNQTIVRKKSEALHPSGPLVILKGNLAPDGAVAKISGLKKISITGPAKVFESEDDCFNAIMTDKIKPGDVIIIRYEGPKGGPGMREMLAVTSALVGKGLGEDVGLMTDGRFSGGTHGLVVGHISPEAFDGGPIAIVQNGDKVTIDSSKNLLQVEISQEEIDKRLKSWKPIEPRYKTGVLAKYVKLVQSATNGAITNLL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GLPK_BRADU
Sequence: MSFVLAIDQGTTSSRAIVFRSDISIAARAQAEFPQHFPASGWVEHEPEDIWTSTVMVCRDAIAQAGISAKDIAAIGITNQRETTVVWDRATGQAVHRAIVWQDRRTADICAKLKADGREPVISEKTGLIIDPYFSGTKVAWILDHVPGARARAARGELMFGTVDCYLLWRLTGGKVHATDATNASRTLLFNIHTGQWDDELLEIIGVPRSMLPEVKDSSARFGESVPDLFGGAIAISGIAGDQQAATIGQACFRPGMMKSTYGTGCFALLNTGTTPVVSKNKLLTTVAYQLDGKRTYALEGSIFVAGSAVQWLRDGLGIIKHAAETGPLADQSDSMQSVYLVPAFVGMGAPYWNPRVRGALFGLTRNTGPAELAHAALESVCYQTFDLWAAMRADWPSSETASVVLRVDGGMTASDWTMQRLADLLDAPVDRPVIQETTALGAAYLAGLNAGVYPEPTKFADNWRLEHRFKPNMSEATRERKLAGWARAVKGVLASDEGA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ATPG_CAMJJ
Sequence: MSNLKEIKRKIKSVYNTQKTTNAMKLVSTAKLKKAEEAAKRSKIYAQKIDEILSEISVQINKIVHNEDDVRLFLFHKKEQIKTVDLIFITADKGLCGGFNIKTLKTVSEMLKEYEAKNINIRLRAIGKTGIEYFNFQKIELLEKYFHLSSSPDYEKACEVIHAAVDDFLNGNTDEVILVHNGYKNMITQELKINHLIPVEPKSIEQTHNSLLELEPEGTELLEDLIKTYFEYNMYYALIDSLAAEHSARMQAMDNATNNAKARVKQLNLAYNKARQESITTELIEIISGVESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HBAD_ANAPL
Sequence: MLTAEDKKLITQLWEKVAGHQEEFGSEALQRMFLAYPQTKTYFPHFDLHPGSEQVRGHGKKVAAALGNAVKSLDNLSQALSELSNLHAYNLRVDPVNFKLLAQCFQVVLAAHLGKDYSPEMHAAFDKFMSAVAAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MEND_TRIV2
Sequence: MPIAYKNINQLWAYVFTETLKRLGLAYAVICPGSRSTPLAVAFAQQAPDIEGISILDERSAAFFALGLAKATNRPVAIVCTSGTAGANFYPAVIEAQESRVPLLLLTADRPPELRDCHSGQTIDQVKLFGSYPNWQTELALPVSDMGMLGYLRQTVIHSWYRMQAPTPGPVHLNIPFRDPLAPIPDGADLSYLLTKFHPEEFFAGITDTTSLPDHSQLSIPPEWLKSQRGIIIAGVAQPQQPQEYCRAIARLSQTLQWPVLAEGLSPIRNYADLNPYLISTYDLILRNQQLATRLAPDMVIQIGDMPTSKELRTWIDTHQPRRWVIDPSDQNLDPLHGRTTHLRIRVEELGCKGVEEDKSSVSEYLQLWCNAETKVRVNVDETLDKMEDLVECKAAWLLSQILPPETPLFIANSMPVRDVEFFWKPNNLRVRSHFNRGANGIDGTLSTALGIAHRHQSSVLITGDLALLHDTNGFLIRNKFVGHLTIILINNNGGGIFEMLPIAKFEPPFEEFFGTPQDIDFAQLCTTYNVQHELIHSWVHLQQRLNPLPNTGIRVLELRTNRKIDAQWRRDNLSNFAADNII
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DSBI_ECOL6
Sequence: MGIKGMWKDLRTSPVDTLVRWQEQRLLWLLMAVAMGALIILAHSFFQIYLYMAPCEQCVYIRYAMFVMVIGGLVAAINPKNIILKLIGCVMAFYGSILGLKFSLKLNDIHHAVHNPDPDSLFGVQGCSTDPTFPFNLPLAQWAPNWFKPTGDCGYDAPIVPDGVTLSSTQQWFVEMYQQSEGWYLLPPWHFMNMAQACMLAFGMCLVLLVIMSGAWALKIIRG
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.
What are the official names of this protein?
Protein-disulfide oxidoreductase DsbI.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. DsbI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_CLOBB
Sequence: MASKKIRTRFAPSPTGYMHVGNLRTALYAYLIAKHEAGDFILRIEDTDQERLVDGAVDIIYNTLKLTGLNHDEGPDVGGEVGPYVQSERKAIYLEYAKNLVEKGEAYYCFCSKDRLDMLKENAEALKRPFKYDKHCLHLTKEEIEANLAKGLPYVIRQNNPTTGSTTFDDVIYGKITVDNSELEDMILIKSDGLPTYNFANVVDDHLMGITHVVRGNEYLSSSPKYNRLYEAFGWDVPIYVHCPPIMKDTHHKLSKRNGDASFEDLIQKGYLKEAVLNYIALLGWNPGTNEEIFSLEELTEKFDFKDISKSPAIFDDAKLKWMNGEYIRKLSLDEFHELAVPEYKKVLKKDFDLKFISDLLHTRCELLSDLADQIDFLEELPEYSTDLYVHKKMKSTVESSLENLEKVLPIIEEIDETNWNKDYIHEKVFELIKSLEIKNGQMLWPIRTALSGKSFTPGGAFELAILLGKEESISRLKKGIELLK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_STRP3
Sequence: MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKEGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYE_YERE8
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFTRHFGGEFVLRIEDTDLERSTQEAIDAIMDGMNWLNLDWDEGPYFQTKRFDRYNAVIDQMLENGTAYRCYCSKERLDELREAQMTNGEKPRYDGRCRDSQCTHGADEPSVVRFRNPQAGSVIFNDKIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGKKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSVAEMTELFTLDAVSKSASAFNTEKLQWLNHHYINSLPPEQVAVHLSWQVEQLGIDTRNGPELVEIVKLLGERCKTLKEMAESCRYFYEEFDEFDADAAKKHLRPVARQPLEAVKAKLAAITEWTTENVHNAIQGTADELGVGMGKVGMPLRVAVTGAGQSPGMDVTVHAIGQARSLSRIDKALAFISEREAQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3M01_CYRHA
Sequence: MKASMFLALAGLVLLFVVGYASESEEKEFPIELLSKIFAVDVFKGEERGCRGFGDSCTPGKNECCPNHACSNKHKWCKVYLGK
What is the function of this protein?
Lethal neurotoxin.  Selectively blocks tetrodotoxin-sensitive voltage-gated sodium channels (Nav).  Does not affect tetrodotoxin-resistant voltage-gated sodium channels or calcium channels (By similarity).
What are the official names of this protein?
Mu-theraphotoxin-Hhn2f, Mu-TRTX-Hhn2f, Hainantoxin-III-13, HNTX-III-13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SLK19_YEAST
Sequence: MNEVPTTPVRLILGQAQQREQNSENCSQERNPRTFNSEPDSSFNSPGSSQFVIHPHEPLEKEKDEKQDLDRSIDYGRSSALNNKNNANPLENIDINKMFDDKKSDSGTNDDKGGASTSDKHVLALNYSPIRVEMNSSEKRSDKNVDVDENDKEGSHINKKLKLQLESVPDLKQSSTKDIINDKEEIMSSPMAIDMIETNISPNKFIINDGVERNDSFNINTDTLKLENDINEKQQEEDFIKSNSNNVVNIDNAYKEKEDEENDITNSHINRLTPLYETSARESNSNEEGRNDYDDDNQLDIRHDNFQIVAKRNEELTDQIYHLNQMLNSLISKNESLSFQYEKLNKNHQLLIDLTNEKLDKLNTERESDIAKVEKFKKRIKELNTEIKVLNSNQKILQEKFDASITEVNHIKGEHENTVNTLQQNEKILNDKNVELENMKAELKGNNDKLSEYETTLNDLNSRIVQLNDKIESTDIVLKSKENELDNLKLSLKETLSISKDFNDSDLIGQINELISTKNNLQQKMDDLNNLNDDNLKVVQDKLIKNEETLKLKEAEIDSLNSEMDELKKQITSKDDEFKMWQSKYETVEDEAKIRNAEVTELNGDIEDLKESKLHLEETITELENKVHKLENECELEKQKFEKTSLELESLQLKNSNIQAEHIKELENLHENLISLQNELKISSDRITTLTKENEVLMEQNNNNNNSVTLSNDQKDRDDEKIKSLGKQVQDWKEKYEAKEKDTNKRLKLLAEDLYIQYSSKHEQKVKLLKKGYENKYQNKFDQLNLENKTLSEEIEQLNKQLSSEREEKQELLKLLENEKK
What is the function of this protein?
Has a role in spindle assembly and stability.  Required to ensure a timely exit form mitosis.  Essential to maintain pre-anaphase spindle polarity.  Associates to the plus ends of the microtubules at the kinetochore and spindle midzone.  A component of the FEAR (CDC14 Early Anaphase Release) network which promotes CDC14 release from the nucleolus during early anaphase.  Required for proper chromosome segregation during meiosis I where it prevents premature sister chromatid separation.
What are the official names of this protein?
Kinetochore protein SLK19, Synthetic lethal KAR3 protein 19.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Spindle midzone during anaphase. During meiotic prophase localizes to the centromere and remains there until anaphase I.
Protein: SEM4F_HUMAN
Sequence: MPASAARPRPGPGQPTASPFPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSAAVMAGGVLYAATVKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVENMKLYHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCPKEPGERPVVFEVPVATAAHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGGAAHVVAAYSLVWGSQRDAPSRAHTVGAGLAGFFLGILAASLTLILIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGGFSPPFLLDPCPSPAHIRLTGAPLATCDETSI
What is the function of this protein?
Probable cell surface receptor that regulates oligodendroglial precursor cell migration (By similarity).  Might also regulate differentiation of oligodendroglial precursor cells (By similarity).  Has growth cone collapse activity against retinal ganglion-cell axons (By similarity).
What are the official names of this protein?
Semaphorin-4F, Semaphorin-M, Sema M, Semaphorin-W, Sema W.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Postsynaptic density. Perikaryon. Cell projection, dendrite. Note=Colocalizes with DLG4 at synapses.
Protein: TILS_CHLCV
Sequence: MLSRLLRDDKLLEVFFSSLDMKKSYLLALSGGSDSLFLLYLLKSRGVAFTAVHVDHGWRESSYREAEELKIRCEEEGIPILIDHVPPEYRTSRDPENAARRYRYTLFHKVCKEQNLAGIFLAHHANDQAETVLKRLLEGASLSNLKGMSPKTSYEDIPLFRPLLHIPKQIIINVLDAENVPCVQDITNTDERYLRARMRKKIFPWLEEIFGKNITQPLLTLAQDSEELSCYMKQQAEPFLENMRKENTTWSIEIPQVLIEQVFLTKWVCKEFFFRAGVVASRHFLQTVYDHLQRKLPAQMRLRDKRVIIKAGVVMIE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_MYCA9
Sequence: MELVVGRIARAHGVTGELSVEVRTDDPDERFAVGSVLTGRLPRGGGSRRFTVESVREHSGRLLIRFAGVSDRDAADALRGTLFMVDTTDLPPIEDPDEFYDHQLEGLAVRTLDGAAVGTVSEVLHTPGGELLSVRGSERREILVPFVSAIVTSISLADKVIEIDPPEGLLDLS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_STAA9
Sequence: MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVKY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.