PharMolix/UniProtQA huggingface dataset:
Protein: UBIQ1_CAEEL
Sequence: MQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLIGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEASDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGDI
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: RRAAH_SACEN
Sequence: MDLSTADLADREGPSVRSCDVQLRNYGGRAVFSGRIRTVRCFQDNALLKQVLSGPGEGDVLVVDGGGSVHTALIGDLIAELGRSNGWSGVVVHGAVRDSAVLAGMEFGVKALGTNPRKSTKTGEGVLDEVVSFGGVDFVPGEHLVSDTDGIVVVASAD
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: DEF3_STRCO
Sequence: MPSVFVQGRPTASYPPFAPEAGRGAVRRVTEVGEEVLHRPCRDVTEFGPDLAALIDDMFRTMYVAEGAGLAANQVGVDLRLFVYDCPDDEGVRHVGHLVNPVLDALDPAARRLLDEGEGCLSVPGAVMAVPRPDRAVVRGLDKDGVPLLVEGTGYFARCLAHETDHVNGHVYLDRLSGRERKAALRQSADRREEVFARRAANAAAFAA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase 3, PDF 3, Polypeptide deformylase 3.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: CRYL1_PIG
Sequence: MASSASSTADGVAVVGSGLIGRSWAMLFASGGFRVKLYDIEQQQVTGALDTIRKEMKLLEQSGALKGSLGAEEQLALISGCSDLREAVEGTVHIQECVPENLELKQQLFAQLDQIVDGNVVLSSSSSCLLPSKLFAGLVHVRQCLVAHPVNPPYHVPLVELVPHPETAPATMARTYALMRQIGQSPVRILKEVDGFALNRLQYALIGEAWRLVEARIVSPGDLDLVMSDGLGLRYAFIGPLETMHLNAEGMLSYCDRYREGMKRVLKTFGPIPEFSGAVAEKVHQAMCVKVPDDPEHLSARREWRDGCLMRLAKLKGQVQPP
What is the function of this protein?
Has high L-gulonate 3-dehydrogenase activity.  It also exhibits low dehydrogenase activity toward L-3-hydroxybutyrate (HBA) and L-threonate.
What are the official names of this protein?
Lambda-crystallin homolog, L-gulonate 3-dehydrogenase, Gul3DH.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP10_RAT
Sequence: MGSLVLPLSAVFCLVARLASGSPIMGLEQSPLEEDMPFFDDIFTEQDGIDFNTLLQSMKDEFLKTLNLSDIPPQDTGRVDPPEYMLELYNKFATDRTSMPSANIIRSFKNEDLFSQPVSFNGIRKYPLLFNVSIPHHEEVVMAELRLYTLVQRDRLMYDGVDRKIIIFEVLESADGSEDERSMLVLVSTEIYGTNSEWETFDITDATRRWQKSGPSTHQLEIHIESRQNQAEDTGRGQLEIDMSAQNKHDPLLVVFSDDQSGDKEQKEELNELISHEQDLDLGTDGFFGGPDEEALLQMRSNMIDDSTARIRRNAKGNYCKKTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLDPISILYLDKGVVTYKFKYEGMAVSECGCR
What is the function of this protein?
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5.  Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors.  Inhibits endothelial cell migration and growth.  May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
What are the official names of this protein?
Bone morphogenetic protein 10, BMP-10.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NKAI2_BOVIN
Sequence: MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCFLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYMQIPLDNN
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_DESHD
Sequence: MKQEVHRIQEETLAELQQVSTLEALQELKVKVLGKKGSLTAQLRKMGGLSPEERPIFGQVVNETRDILEAAWVRREEELSQAAMLKQLEEEKLDISLPGVSLPRGHQHPLTKVIEEIEEIFLGMGFQIAEGPEIESDYYNFEALNLPKDHPAREMQDSFYITEEILLRTQTSPVQIRTMEKQRPQLPVKIICPGKVYRNDDDATHSPMFHQVEGLMVDRGIRMSDLKGILLSFSRMMFGESREIRLRPSFFPFTEPSAEVDVSCMLCGGAGCRICKGTGWIEILGSGMVHPRVLEMGGYDSKELTGFAFGMGVERIAMLKYGIEDMRLLFDNDLRFLQQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODAM_MACMU
Sequence: MKIIILLGFLGATLSAPLIPQRLMSASNSNELLLNLNNGQLLPLRLQGPLNSWIPPFSGVLQQQQQAQIPGLAQFSLSALDQFAGLFPNQIPFPGQASFAQGAQAGQVDPSQAQTPPQTQPGPNHVMPYVFSFKMPQEQGQMFEYYPVYVLLPWEQPQQTVPRSPPQTRQQQYEEQIPFYDQFGYIPQLAEPAIPGGQQQLAFDPQLGTAPEIAVMSTGEEIPYLQKEVINFRRDSAGVLMPSTSPKPSTTNVFTSAIDRTITAKFPEEKAKTDGLREP
What is the function of this protein?
Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth.  May be incorporated in the enamel matrix at the end of mineralization process.  Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK.  Plays a role in attachment of the junctional epithelium to the tooth surface.
What are the official names of this protein?
Odontogenic ameloblast-associated protein, Apin.
What is the protein family that this protein belongs to?
Belongs to the ODAM family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Nucleus.
Protein: P49_ASFM2
Sequence: MYHDYASKLLADYRSDPPLWESDLPRHNRYSDNILNSRYCGNKNGAEPVYNESTNSPGKAERGLQLSDLRNFSFMLNPQHKNIGYGDAQDLEPYSSIPKNKLFNNFKNHRPAFSTHTENLIRRNVVRTEKKTFPQVASLKSTQKHCLTQPSSLPSLKNPKNISVPSARFSEHTKFFSYEDLPKLKTKGAIKHEQHLGDQMSGQYYNGYIPHKDVYNILCLAHNLPASVEKVIAGRGIPLGNPHVKPNIEQELIKSACAYTGIPIGPLPSKDLQHGREYQEFSANRHMLQVSNILHSVFANHSIKPQILEDIPTLNAQLTSIKPISPFLNKAYQTHYMENIVTLVPRFKSIANYSSPIPNYSKRDSGQAEYFDTSKQTISRHNNYIPKYTGGIGDSKLDTTFPKDFNASSVPLTSAEKDHSLRGDNSACCISSISPSL
What is the function of this protein?
Together with the penton and the other minor capsid proteins (M1249L, p17), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (By similarity).  Plays an essential role in the formation of infectious virus particles.  Especially required for the formation of the capsid vertices (By similarity).  During virion assembly, associates with the membrane and probably mediates the docking of the penton complex to the inner membrane, where it recruits the capsomers to form the penton core (By similarity).
What are the official names of this protein?
Minor capsid protein p49, p49.
What is the protein family that this protein belongs to?
Belongs to the asfivirus p49 structural protein family.
What are the subcellular locations of this protein?
Virion. Note=Localizes in close proximity to the capsid vertices.
Protein: AHL27_ARATH
Sequence: MEGGYEQGGGASRYFHNLFRPEIHHQQLQPQGGINLIDQHHHQHQQHQQQQQPSDDSRESDHSNKDHHQQGRPDSDPNTSSSAPGKRPRGRPPGSKNKAKPPIIVTRDSPNALRSHVLEVSPGADIVESVSTYARRRGRGVSVLGGNGTVSNVTLRQPVTPGNGGGVSGGGGVVTLHGRFEILSLTGTVLPPPAPPGAGGLSIFLAGGQGQVVGGSVVAPLIASAPVILMAASFSNAVFERLPIEEEEEEGGGGGGGGGGGPPQMQQAPSASPPSGVTGQGQLGGNVGGYGFSGDPHLLGWGAGTPSRPPF
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (PubMed:17971039, PubMed:19517252).  Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered FRK1 expression (PubMed:20738724).  Acts redundantly with AHL18, AHL22 and AHL29 in the regulation of flowering and regulation of the hypocotyl elongation (PubMed:19517252).  Acts as a chromatin remodeling factor that negatively regulates the leaf senescence (PubMed:17971039).  Acts redundantly with AHL29/SOB3 to modulate hypocotyl growth inhibition in response to light (PubMed:18088311).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 27, DNA-binding protein ESCAROLA, Protein ORESARA 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENTS_ECOL5
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSVRPGLLMLLSTLGAFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQVTASGS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FPG_RUEST
Sequence: MPELPEVETVMRGLQPSMEGVVIARADVNRPDLRWPFPDRMTERLSGRRVLSMRRRSKYILADLDSGETLLVHLGMSGRMTVSGDPLGQFVHSHPQLEKHDHVVFHMDNGARVTFNDPRRFGAMDLLETAKADSHKLLAVLGPEPLGNDFHESHLVSAFKGRRTPVKSALLDQGIIAGLGNIYVCEALFRAGISPRREAGKISTSRVTSLVPIIRQVLQDAIAAGGSSLKDFRQANGELGYFQHTFDVYGREGEPCRRAGCTGTVTRITQSGRSSFYCGKCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PCDC1_HUMAN
Sequence: MVGCGVAVLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLLSNSVPQLLPDFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCRSTEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADLRNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-C1, PCDH-alpha-C1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: INHA_MYCAV
Sequence: MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRIVDRLPEKAPLIELDVQNEEHLNTLAQRVTGEIGEGNKLDGVVHSIASSETGMADQPFFDAPYEDVSKGIHISADSDASLAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAMAGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSDWLPATTGTIIYADRGASTQLL
What is the function of this protein?
Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls.  Catalyzes the NADH-dependent reduction of the double bond of 2-trans-enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway.  Shows preference for long-chain fatty acyl thioester substrates, and can also use 2-trans-enoyl-CoAs as alternative substrates.  The mycobacterial FAS-II system utilizes the products of the FAS-I system as primers to extend fatty acyl chain lengths up to C56, forming the meromycolate chain that serves as the precursor for final mycolic acids.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR, Enoyl-ACP reductase, FAS-II enoyl-ACP reductase, NADH-dependent 2-trans-enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: YI047_YEAST
Sequence: MNMLPMFTYSGLPVTLLCLIQLRRSVMILWIVVIWVQKPFHHLTTYLSRLHMTIILTVLPNLCPLTVGLSEEGPPCLRTFRDPFLGHMQLISKDQLSIPWMIGLPKQIVKVKWKVLCDLGWT
What are the official names of this protein?
Putative uncharacterized protein YIL047C-A.
Protein: AMPA_STRGG
Sequence: MTALTLSTAGAATLRADALVVGVAKGVKGPVLAPGSEAVDKAFDGKLAAVLATLGATGAEGELTKLPAASGLKAPVVVAVGLGPVPDKEDAYDAEALRRAAGTAARALTGSKKAGFALPAASVEDAAAVAEGALLGAYAFTAYQGGENKLAPKDAKSKGNGPKLPLAEVALLGAKPRDKAYKAAVERSLALVEEINRARDLVNTPPNDLYPESFAAVATAAGKEHGVKVQVLDEKALVKGGFGGILGVGQGASRGPRLVKLAYTHPKAEKTLALVGKGITYDSGGISLKPAGHNETMKCDMAGAAAVFAAVVTAARLGLKVNVTGWLALAENMPSGNATRPGDVLRMYSGKTVEVLNTDAEGRLVLADALTRASEEKPDAIVDVATLTGAMVLALGNRTFGVMANDDAFRTSLHEIAEEVGEPSWPMPLPADLRKGMDSPTADIANMGERMGGGLVAGLFLKEFVGEGIAWAHLDIAGPAFHEGAPYGYTPKGGTGSAVRTLVRLAERTAAGDLG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_ECOBW
Sequence: MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_SERP5
Sequence: MQKFDTKTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGLDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGMECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGVTTYGDVFHQNEVEQSTYNFEYADVDFLFSCFEQYEKEAQSLLALEKPLPLPAYERILKAGHTFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCKKNKS
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_AERHH
Sequence: MQKRIVSSLYFQVLLAITLGVILGHIYPDLGADMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGKTGAIALLYFEVVSTIALIIGLCVVNLLQPGAGMNVDPATLDASAISAYAEQAKAQGIIPFLLDVIPGSVIGAFASGNILQVLLFAVLFGFSLHHIGEKGKVIFNVIDSFSQVIFGIINMIMRLAPVGAFGAMAFTIGKYGIGSLVQLGQLIACFYMTCLLFIFLVLGSIARANGFSILRFISYIREELLIVLGTSSSESVLPRMLVKMEALGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAIFIAQATNTPLDLFQQITLLVVLLISSKGAAGVTGSGFIVLAATISAVGHLPLAGLALILGIDRFMSEARALTNLIGNGVATLVVARYCDQLNEQQMHEALSNPPQVVKLDQH
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MENC_ECOUT
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEDAQSVLLAWVNNWLAGDCEIPQMPSVAFGVSCALAELAETLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLDKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSPLPLVDVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: RL23_SHISS
Sequence: MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUSB_THEP3
Sequence: MNRTEAREWVVKMLYQYDVSRLPISKILENFYKEKDPGEQKEYIENTVIGAIEHLEEIDKEIERYSQNWALNRMPKIDLAILRCSIYEMQYGNIPVNISINEAVEIAKKYSTEDSPAFINGLLGAFVRDEGLEEGESNDN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CPFC_LISMO
Sequence: MTKKVGLLVMAYGTPYKDEDIERYYTDIRHGHKPSEEMIADLRGRYHAIGGLSPLAKITEAQAYGLEKALNDSQDEVEFKAYIGLKHIEPFIEDAVEAMHKDGIEEAISIVLAPHYSSFSVEAYNKRAKEAADKLGGPRINAINDWYKQPKFIQMWADRINETAKQIPADELLDTVLIVSAHSLPEKIKQHNDPYPNQLQETADFIFEKVVVPHYALGWQSEGKTGEPWLGPDVQDLTRELYGREKYKHFIYTPVGFVAEHLEVLYDNDYECKVVTDEVGAAYHRPPMPNSDPEFLEVLRTVVWEKYSN
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:31794133).  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:31794133).
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_SALAI
Sequence: MPRSLKKGPFIDDHLLKKVETQNDKGTKNVIKTWSRRSTIIPEMLGHTIAVHDGRKHVPVFVTEAMVGHKLGEFALTRTFKGHEKDDRKSRRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RIMP_STRAW
Sequence: MSTTQSERLRELLEPLVGSQGLDLEGIEVESVGRKRVLRVVVDSDEGADLDAIADVSRALSAKLDETDAMGEGEYTLEVGTPGAERALTEHRHYVRAVDRLVRFQLTEGDELVARILTVDDAGLDLEVPGVKGRKATTRRLAFEDIAKARVQVEFNRKDKKDMTEEEEA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.