PharMolix/UniProtQA huggingface dataset:
Protein: VLN4_ORYSJ
Sequence: MSISMKDVDPAFRGVGQKDGLEVWRIENFKPVPVPTSSHGKFYMGDSYIILKTTALKNGSFRHDLHYWLGKDTSQDEAGTAAILTVELDAALGGRAVQYREVQGGETEKLLSYFRPCIMPQPGGVASGFNHVEVNQQDHVTRLYVCQGKHVVHVKEVPFVRSSLNHEDIFILDTANKIFQFNGSNSCIQERAKALEVVQYIKDTFHEGKCEVAAVEDGKLMADTEAGEFWGLFGGFAPLPKKTSSEDNGDDKETVTKLLCFNQGTLEHISFESLEHELLETNKCYLLDCGAEMYVWMGRGTSLQVRKGASEAAEKLLIDENRKGSNVIKVIEGFETIMFKSKFNKWPPTPDLKLSSEDGRGKVAALLRSQGLDVKGLMKAAPEEEEPQPYIDCTGHLQVWRVNGDGKTLLSSSDQSKLYTGDCYIFQYTYTGDDKEECLIGTWFGKKSVEEDRTSAISLASKMFQAAKFQAAQARLYEGKEPIQFFVIFQSLQVFKGGLSSGYKNFIAVNGTDDDTYVEGGLALFRIQGSGSENMQAIQVDAVSSSLNSSYCYILHNGNTVFTWTGNLTTSLDNDLVERQLDVIKPDLPSRSQKEGRETDQFWELLGGKCKYSNKKIGKENESDPHLFSCILSKENLKVKEIHHFTQDDLMAEDIFVLDCRTDLFVWVGQEVDAKLRSQAMDIGEKFLLHDFLMENLSQDTPIFIVTEGSEPQFFTRFFTWDSAKSLMHGSSYQRKLAIVKGGATPSLDKPKRRTPAFSGRNAGQDKSQQRTRSMSHSPERHRIRGRSPAFTAIASAFENPSTRYLSTPPPAVKKLFPRSGGSELPKTSSKQSAINALTSAFEGPTKSTIPKSVKASPEAEKAIQEEGSTIGESENEPEDDENSTIYPYERLTTTSDDPAPDIDVTKREVYLSSVEFTEKFGMTRASFKNLPKWKQNRLKSDLQLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein (By similarity).  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Villin-4.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: EX7S_LEGPC
Sequence: MSKGIHFEQSITELEEIVRQLEKGELTLEESLKQFEKGISLARRCQNALNQAEQKIETLTGTDSNIELDSDEQTSD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_ECOK1
Sequence: MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTNCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: NNRD_DICDI
Sequence: MTHLIDLFKPMIPSLLNNLHKGQSGRIAIMGGSKEYTGAPFFSGISSLKIGSDICHIFAPTEGGTATALKTMSPDLIVHPIEKNDPSDIIPWLLSLHVIVVGPGLGRSSGAWSCASEVIKAARNINLPIVLDGDALRLICDNLDIIKGYDKAILTPNFVEFKSLSDSVKKMIGDTSNNLLKPEHIASCLGNITIVQKGKEDIITDGNQTVVCDDEGMPRRCGGQGDILAGTVGTMYAWSQLYYKYNSNTDDKPEYPISIISAYAACSLLRHCSKKAYQISKRSTVSMDIINQISNGFEDLFPESSK
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: RR14_OEDCA
Sequence: MAKISLIQREFKRQRLVLKYEKKRTFLKREIQRTPFLKQKLQFHRILQQLPRNSASVRLHNRCLVTGRSRGYYRDFGLSRHVLREMAHQGFLPGVIKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KHSE_SYNR3
Sequence: MGKPEIGTTVVVDVPATTANLGPGFDCLGAALDLNNQFQLKVLEGGAERFELIIESKEGSHLRGGPDNLVYRAAQRVWREVGMQPIALEARVQLAVPPARGMGSSATAIVAGLMGANALAGEALGKEKLLELAIDIEGHPDNVVPSLLGGLCLTAQAASRRWRVVRCEWHENVQAVVAIPSIRLSTADARRAMPKQIVVPDAVSNLGSLTLLLQGLRSGNGDLITDGMHDRLHEPYRWPLIQGGSAVRKAAMDAGAWGCVISGAGPSLLALCPPDKGRAVAEAMEKSWEQEGVQTRALPLKLQSGGSRWRPKPS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_FRATF
Sequence: MSRISSLQDPFLNALRKEKVSVSVYLVNGIKLQGQVEAFDQFCIVLRNTVNQMVYKHAISTIVPAKSVRMVYSSFNPYHQNSNDEQDENVDDIHSDDLEIQENEGNIHE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CLPX_EHRCR
Sequence: MADNEKNSCSCSFCGKIHSEVRKLIAGPSVFICNECIDLCSGILQEESRSYKKTDTLKLKPKEIKKVLDEYVIGQEHSKKVLSVAVYNHYKRLSNLSVISEVEISKSNVLLIGPTGSGKTLLARTLARVLQVPFAMADATTLTEAGYVGEDVENILLKLLQAANFNVDAAQRGIIYIDEVDKISRKSENTSITRDVSGEGVQQALLKVIEGTVSSVPPQGGRKHPHQEFIQINTDNILFIFGGAFDGLDKIIESRHRGSSMGFEANVQKVSKNKDIFCYTEPEDLVKFGLIPEFVGRIPVITSLGELDESTLCRILVEPKNSLVKQYKKLFEMDNINLQFDDSALSVIAKKAAVRKTGARGLRAILEALLLDLMFESPGSSDVNQVVISKEMVEELMVSSHLFLKH
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: APAH_AROAE
Sequence: MAIYAIGDIQGCFREFRELVDQCGFDPSSDRLWLVGDLVNRGPASLETLRFVRSLGDAAVSVLGNHDLYLLKIAYAGASGRKRHDTLQQVLEAPDRDELIAWLRTLPLMHLEGGYAMVHAGLLPGWTAEPARALAREVEAVLSGDSCEAFLQHMWGNSPKAWRDDLAGWERLRVIVNAMTRMRFCTPDGRMEFDAKGPPDSAPPNHLPWFAHPNRASSDTTIVCGHWSALGLRMEPNLLALDSGCVWGEKLTAVRLEDRRVFQVHAGKQLGSF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: DADH_EGGLN
Sequence: MGNLTMSRRTFVKTAAITGAAAAAFGASTHTALAEETYSSVSGNDTVAVKTCCRGCGKMECGVKVIVQNGRAIRVEGDEGAFQSMGNCCTKSQSSIQAAYHPDRLHYPMKRTNPKGEEPGWQRISWDEAMQSIVDNFMDIKAKHGGEAIACQVGTSRIWCMHSESILKNMLETPNNVEAWQICKGPRHFATTMVSQFAMSWMETITRPKVYVQWGGASELSNYDDSCRTTVDVASRADVHISVDPRMANMGKEADYWQHLRPGTDGALALAWTNVIIEKKLYDELYVKKWTNAPFLVCEDMEPSGFPTVRTDGSYWDVKTALLKESDIKEGGSPYKFLVYDNNWEKLKAEGVEHEYGAFTWFNADQEGVIDETGGFWEGENYDSEKARQGREAAQDNLLPGQTQGWLPDPMPFDPAIDPALEGEFEITLKDGKTVKVKPVWEHYKARAAEYKPEVAAEITGIPASEIEAAATAYGTRIDPSTGYGNGGIQYMLAVEHFCSAIQNCRAFDNLVGITGNMDTPGGNRGPTIVPIDGDLQGFSAWAPGATTPPEEVNRKQIGIDKFPLLGWWQYWCDSHSLWDAVITGDPYPVRALWNESGNFMSQTNTTRAWEALCSLDFYVDLNLWHTPQNDTADIILPVAHWIELNSPRASQGSAGAMGATVKCVQPPAEAKYDPEIVMDLARRMNWKWTDEPGNEWPDINWQLDDSIKLLTDDELTYTTWHVENGKPTFERHGVPMAEVTPKYKTWDEYVKAFQEHGWWQAKDIEPRNWGTYRRYQTGAMRARDRVWGRLDYTAGKGIGDWKPGWFTPTMKQEIWSTVMESHHPDHPEWRLPTYTEPPHGPKDGDRIKEYPLTATTGRRIPVYFHSEHRQLPWCRELWPVPRVEINPKTAAEYGIEQGDWVWIETEWGKIREVADLYYGVKEDVINLEHTWWYPEVKDAGHGWQFSQVNQLIDHYAQDPHSGTSNLRAYQVKIYKATPENSPFNNPVPCDSTGTPIIHTSDDPRLKEWLPTYEGRE
What is the function of this protein?
Involved in drug metabolism, as part of an interspecies gut bacterial pathway for Levodopa (L-dopa) metabolism, acting on dopamine produced by Enterecoccus L-dopa decarboxylase.  Removes the para hydroxyl group of dopamine to produce m-tyramine (3-tyramine).  It is possible that dopamine dehydroxylation influences the multiple side effects of L-dopa administration linked to dopamine production in the treatment of Parkinson's disease.
What are the official names of this protein?
Dopamine dehydroxylase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: SYGB_LIMRJ
Sequence: MANTYLLEVGVEEMPAHVVTPSIKQLHERVAKYLKEQRITFDDIQEFATPRRMALLIHGLSDKQPDIDESVKGPAKKIAQDADGNWTKAAIGFTRGQGASVEDIEFKEVKGVEYVFVEKHIAGKTVAEVLQGLPAVITSMTFPTLMKWGYNNLQFIRPIRWLVSLLNDEVVPFNILDVEAGRETQGHRFLGHPVEIAKADDYEETLNNDFVIADQTKRKNLIKDQITKIINENNWQVDWDEDLLEEVNNLVEWPTAFAGSFDEKYLALPDPVLITSMKDNQRFFCVRDGDGNLLSHFISVRNGNTDYLDNVIKGNERVLVPRLEDAQFFYQEDQKLTIDEYVERLKKVSFHDKISSMYDKMQRVAVIANVLGKQLNLSDEELADLDRAAHIYKFDLTTQMVGEFAELQGIMGEIYAKLFGEKDDVATAIREHYMPISAEGELPQTKIGAVLAIADKLDSIMSFFAVDMIPSGSNDPYALRRQAFGIVRIIADRGWHLPLLSIQSEIAPAFENAEINVSFDLNKNSDEVRSFFLDRIKQLFHGQKVRHDIIDAATDTRQNDIANILEAIQTIDDHKDDDNFKEDIEALTRVLRIAKKDKRPVSELVVDPNLFENPSEAKMHTAVSELIKENQQTVSENFAALRTLTPIISEYFDENMIMDKNEDIRNNRLAQLSILAHQASLIGNLDNLIVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2933_SHEB2
Sequence: MLGWTLVFLVVAVIAGLLGFTGIAGAAAGIAKIIFLIFIVLLVISLLVNAFRGKSPRL
What are the official names of this protein?
UPF0391 membrane protein Sbal223_2933.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_GLUOX
Sequence: MKRTYQPSKLVRKRRHGFRTRSETVGGRRVLANRRSKGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TRPE_BACSU
Sequence: MNFQSNISAFLEDSLSHHTIPIVETFTVDTLTPIQMIEKLDREITYLLESKDDTSTWSRYSFIGLNPFLTIKEEQGRFSAADQDSKSLYTGNELKEVLNWMNTTYKIKTPELGIPFVGGAVGYLSYDMIPLIEPSVPSHTKETDMEKCMLFVCRTLIAYDHETKNVHFIQYARLTGEETKNEKMDVFHQNHLELQNLIEKMMDQKNIKELFLSADSYKTPSFETVSSNYEKSAFMADVEKIKSYIKAGDIFQGVLSQKFEVPIKADAFELYRVLRIVNPSPYMYYMKLLDREIVGSSPERLIHVQDGHLEIHPIAGTRKRGADKAEDERLKVELMKDEKEKAEHYMLVDLARNDIGRVAEYGSVSVPEFTKIVSFSHVMHIISVVTGRLKKGVHPVDALMSAFPAGTLTGAPKIRAMQLLQELEPTPRETYGGCIAYIGFDGNIDSCITIRTMSVKNGVASIQAGAGIVADSVPEAEYEESCNKAGALLKTIHIAEDMFHSKEDKADEQISTIVR
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: BIOA_GEOSL
Sequence: MPDYDTQTLRDWDRRHIWHPFTQMKEWEESEPVVIVEGEGSWIIDSEGKRYLDGVAAIWTNVHGHCRREINEALKAQVDRLEHSTLLGLTNDRAVVLAKRLAEIAPPGLCKVFYSDNGSTAVEVGVKMAFQFWRHEGKPEKSRFISFTSAYHGDTLGAVSVGGIDLFHGVFRPLLFPTIQAPAPYCYRCPMGRDTPAACGMECLTELERIMESHAGEVAGLVIEPLVQGAGGMIVQPEGFLKGVRELCDRHDILMIADEVAVGFGRTGAMFACGREGITPDIMALSKGITAGYMPLAATLATQQVYDAFLGEYREMKTFFHGHTFTGNPLGCAVALASLDLFESDRLLGKLPNKIKLLQEKLKGLIELEHVGDVRQCGMIAAVELVRDRATKEPFDWEERVGVRVCLEARTHGVFLRPLGNVIVIFPPLAITAEEIDFLVDGLEKSIHTVTGG
What is the function of this protein?
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).  It is the only aminotransferase known to utilize SAM as an amino donor.
What are the official names of this protein?
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, 7,8-diamino-pelargonic acid aminotransferase, DAPA AT, DAPA aminotransferase, 7,8-diaminononanoate synthase, DANS, Diaminopelargonic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_THEMA
Sequence: MTQMEMARKGVVSDEMKKVAEYEGVDVEIVRQKLAEGRAVLPKNKLHRIERPMIVGEGFSVKVNANIGTSQGFSSLEEEKEKARVAIEYGADSLMVLSTWGDLREIRRAIVEMSPVPVGSVPIYDSAVRSYQMKKNVVDFSEKDFFDMVIAHAEDGIDFMTIHVGVTRRVLDRIKSSRRVLKIVSRGGAIIAGWMIKNNKENPFYEHFDELLDIAKDYDITLSLGDGMRPGAVVDASDAQQFEELFVMGELVERAREKGVQVMLEGPGHVPLNEVEMNVRLMKKIGKGAPIFLLGPLPTDRAMGYDHIACAIGGALAGYYGADFLCYVTPSEHISLPDVEDVREGVIASKIAAIVADVARGNKKAWELEKKMALARKNFDWETMFSLSLGKDVAKKKYEERPYPDKGCSMCGPFCAIKIAEEFS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TRPD_PROM9
Sequence: MSFNISNAEILNILLEGGNLDELTSSLLMQRWLNDEISDVQTGAFLSALRAKGCTGVELSSMAEELLKVCELPVARPNLYMVDTCGTGGDGANTFNISTAVAFVAASCGAKIAKHGNKSASGKVGSADVLLNLGLNLNCSLKKVISAVNEIGITFLFAPVWHKSLIKLAPLRKALGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLEPMGSALLKMGMNRVIVVHGSGGLDEASLQGDNKLVFVEKGKLRFSKINILDFNHENIPNDKLVVSGSDSNEEILKSVLNGSGQKSHKDVVALNAALVLWAAGIEDDLHKGFNKALFSINQGNPWEKFLLLKTYLSSDDLISP
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CYB_MONAD
Sequence: MTNLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLFKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALVIVHLLFLHETGSSNPTGINPDSDKIPFHPYYTIKDALGLILMILILMSLAMFSPDMLGDPDNFTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLLIIPLLHTSKQRSLMFRPISQVLFWMLTANLLTLTWIGGQPVEQPFIIIGQLASILYFSLIIIFMPLAGMLEDYMLEPKFP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFP_PETMO
Sequence: MIDVGDLRKGDMIVYQNEMYRVIEANKHFMGRGSGLIRTRLKSVITGLIKEVSFSSGEKVEEADISFRKAQYLYNDGDHYYFMLLDTYEQYSLPAQELEDEKFYLTENLEVDLIFFNGNPVSIQLPTVVVLTVIDTEPNFKGNTVSGGGKPATLETGLKTTVPFFVERGQKIKVDTRTGDYLERA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_THEGJ
Sequence: MPIDAWVREEVEIPEGVEVTVENNVVKVKGPKGELERELKYPGVKIFTEDGKVVVYKEFPRKKDIAIARTFKAHINNMIKGVTEGFTYKLKVVYSHFPVTVKVQGDEVIIENFLGEKNPRRAKILPGVTVKVRGQEITVEGIDKEKVGQTAANIEQATRITKWDRRVFQDGIYIVEKAGKPIKF
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: AMPA_HAHCH
Sequence: MNYSALSTDPIKQKSDCLVVGVVEGKTQSAVWTELDQQCKGVLGKLLSSGDISSKLATTSWFYPQEGGVKRLLFVGLGKEKELSEAGFRKAAKSVMQSLSKSGAANAVVALSSLTLNSLKAGWATEQLVIALESACYTFDNMKSEKATPTKVSQVKVAGDKRDKSAIEAAIAKASAVAKGMSLTKDLGNLPGNVCTPDYLAKQAKALAKEYKSLKAEALGEKEMKELGMGSFLSVSAGSDQPARLIVIEYKGGDDKQKNHVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAASVFGTLLALAEMKAPVNVVGVIAAAENMPSGKATKPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYCERFKPETVVDIATLTGACIIALGNHATGLLANDDKLADALLAAGESTGDRAWRLPLWDEYQTQLDSNFADMQNIGGRPAGTITAACFLSRFTKKYRWAHLDIAGVAWTSGKDKGASGRPVPLLTEYLLGQVKG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_XYLFA
Sequence: MASYGMNDVKNGMKILVNAEPAVITDTEYVKPGKGQAFTRVKYRLIKSGRVQEVTMKSTDTLEAADVVDTDMQYLYSDGEYWHFMQQETFEQVQADKNGMGGAEKWLKGEEQCVVTLWNGVPIGVQPPNFVELKITETDPGLRGDTSGGGGKPATLETGAVVRVPLFVNQDEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHR_METTM
Sequence: MIHDERIRSLNTEKPARDGKYVIYWMQASVRAHWNHALEYAIETANSLHKPLIVIFGLTDEFPNANSRHYRFLIEGLRDVGDALMKRGARLVVENERPPSAVMRYSDEASAVVVDRGYLDIQKEWVDELAESLHVPLMQVESNVIVPVETASPKEEYSAGTFRPKITRELERFMVPLKERRLAVDSLDLDPGPDLNDVTGKFRASEELEPSIFSGGASEAIRLFDEFLSEKLACFEKYRNDPVKNCLSNMSPYLHFGHISPLYLAMKASKTGECPEFLEELIVRRELSMNFVHYSDNYSSIRCLPEWAQKTLMEHARDPKEYEYTLREFEEARTHDPYWNAAQKEMVITGKMHGYMRMYWGKKILEWTDHPERAYDIAIYLNDKYEIDGRDPNGFTGVAWCFGKHDRAWAEREIFGKVRYMNDRGLERKFRIGEYVRRVQELEE
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-2 family.
Protein: TRMD_MYCLE
Sequence: MKIDIVTIFPAYLDPLRQSLPGKAIESGLVDVQVHDLRRWTHDVHHSVDDVPYGGGPGMVMKAPVWGEALDEICFDETLLVIPTPAGALFTQATAQCWSTERHLVFACGRYEGIDQRVVDDAVRRMRVEEVSIGDYVLPGGESAAVVMIEAVLRLVAGVLGNPASHRDDSHSPDLGRLLEGPSYTRPPTWRGLDVPPVLLSGDHARIAAWRREASLRRTRKRRPDLSGARFVWGLGLS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKX61_RAT
Sequence: MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGAHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSSGGSLLLHASEAEGSS
What is the function of this protein?
Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes.  Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity).  Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube.  Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).
What are the official names of this protein?
Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROA_ERWT9
Sequence: MQDSLTLQPIALVDGTVNLPGSKSVSNRALLLAALAEGTTRLTNLLDSDDVRHMLDALKAIGVKYSLSADRTCCEIVGQGGPLNAKEPLELFLGNAGTAMRPLAAALCIGNGDVVLTGEPRMKERPIGHLVDALRQGGAEVEYLEQENYPPLRVKGGFSGGEVTVNGSVSSQFLTALLMAAPLAPNDTRIVIKGDLVSKPYIDITLKLMATFGVVVENNDYDTFHISGQQQYQATREYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIHFADVLEKMGASVEWGDDYIACTRGDLNAVDLDMNHIPDAAMTIATTALFAQGTTVMRNIYNWRVKETDRLTAMATELRKVGAEVEEGHDFISITPPAKIVFAEIGTYNDHRMAMCFSLVALSSSPVTILDPKCTAKTFPDYFEQLARLSHLA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUNK_FUSOX
Sequence: MRSYTLLALAGPLAVSAASGSGHSTRYWDCCKPSCSWSGKAAVNAPALTCDKNDNPISNTNAVNGCEGGGSAYACTNYSPWAVNDELAYGFAATKISGGSEASWCCACYALTFTTGPVKGKKMIVQSTNTGGDLGDNHFDLMMPGGGVGIFDGCTSEFGKALGGAQYGGISSRSECDSYPELLKDGCHWRFDWFENADNPDFTFEQVQCPKALLDISGCKRDDDSSFPAFKGDTSASKPQPSSSAKKTTSAAAAAQPQKTKDSAPVVQKSSTKPAAQPEPTKPADKPQTDKPVATKPAATKPAQPVNKPKTTQKVRGTKTRGSCPAKTDATAKASVVPAYYQCGGSKSAYPNGNLACATGSKCVKQNEYYSQCVPN
What are the official names of this protein?
Putative endoglucanase type K, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 45 (cellulase K) family.