PharMolix/UniProtQA huggingface dataset:
Protein: SELO_BACCN
Sequence: MEKKTKRQETGWNFDNSYARLPESFFSKLLPAPVRAPKLVVLNDSLATSLGLDAEALKSEEGVAVLAGNKVPEGASPLAQAYAGHQFGHFNMLGDGRALLISEQITPSGQRFDIQLKGSGRTPYSRRGDGRAALGPMLREYIISEAMYALGIPTTRSLAVTTTGESIFRETELPGAILTRVASSHIRVGTFQYAAATRSIEDLKSLADYTIKRHFPHIEAHETPYLALLQEVIERQASLIAKWQLVGFIHGVMNTDNMTISGETIDYGPCAFMDTYNPVTVFSSIDMQGRYAYGNQPYIGVWNLARLAESLLPLLHTDIEQAAQIAQNTISKFGPLYEKHWLAGMRAKLGIFNEEATDKELMEELLNTMEKYRADYTNTFLALTFDTNKDTDFFKSEAFTSWHKKWEERLSRQEESKSSSQQLMRDNNPAIIPRNHRVEEALEAAVKQEDYRVMERLLAALSSPYAHSPEQYEYATVPEPSTQPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL32_SYNP2
Sequence: MAVPKKKTSKAKRDQRRAHWKRKATIEAQKALSLGKSVLTGRSSFVYPSPEDDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: Y667_CHLMU
Sequence: MLEGFWVLEIRVTTKARENKVVSLEDGILRVRVTEAPERGKANDAVVALLAKFLSIPKNDVTLIAGEASRRKKVLLPRAIKAFLFEQFPQTSSPDAGKKC
What are the official names of this protein?
UPF0235 protein TC_0667.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: FADR_VIBC3
Sequence: MVIKAKSPAGFAEKYIIESIWNGRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLLAARTNISPIFMRYAFKLNKESAERIMINVIESCEALVNAPSWDAFIAASPYAEKIQQHVKEDSEKDELKRQEILIAKTFNFYDYMLFQRLAFHSGNQIYGLIFNGLKKLYDRVGSYYFSNPQARELAMEFYRQLLAVCQSGEREHLPQVIRQYGIASGHIWNQMKMTLPSNFTEDDC
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ECOSM
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQHCRTTTRELASALEMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BORPE
Sequence: MARYIGPKCKLSRREGTDLFLKSARRSLDSKCKLDSKPGQHGRTSGARTSDYGLQLREKQKLKRMYGVLEKQFRKYFVEAERRRGNTGETLIQLLESRLDNVVYRMGFGSTRAEARQLVSHRAIELNGHTADIASMLVKAGDVISIREKAKKQGRIRESLDLAASIGLPQWVEVDASKMTGTFKSAPDRADVARDVNESMVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RM53_PONAB
Sequence: MAAALARLGLRPVKQVRVQFCPFEKNVESTRTFLQAVSSEKVRSTNLNCPVIADVRHDGSEPCVDVLFGDGYRLIMRGAHLTALEMLTAFASHIRARDAAGSGDKPGADTGR
What are the official names of this protein?
39S ribosomal protein L53, mitochondrial, L53mt, MRP-L53.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOA_OLEA2
Sequence: MLIKQGDRLINTRNWSELVKPDQISRASESADTMYGKFVCEPLERGYGTTIGNAMRRVLLASLQGAAFVAVKISGVQHEFTTIPGVLEDVTDIVLNLKQVRLAMDTEEPQHLELHVNKSGEVKAGDIKCNQHVMVLNADQHLMTLTEDVELTFELEVRMGKGYVPADMHEGLSDEIGLIALDASFSPVRKVAYTVEQARVGQMTNYDKLILEVWTDGSISPEDAIAYSAKIIKDQISVFINFDERISEQENEGRSSASDVNENLFKGIDELELSVRATNCLKSANISLVGELVQKSEGEMLKTKNFGRKSLDEIRRVLGEMSLDFGMKVDGFEKKYQEWLKRKQQNEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TCTP_ASPOR
Sequence: MIIYKDILTGDEIISDAFNLKEVDNILWEVDCRNITIGDENIQLEGANPSAEGEDDDAGGAGNAEQVLDIKHNFRLNDYPKLEKDEYKKAIKGYMKKVLAKLEEKKAPEETIKEFKENAQTALKRILANYKDYDVLVGESFGADAMHILINYREDGVTPYATFWKHGLEEYKV
What is the function of this protein?
Involved in protein synthesis.  Involved in microtubule stabilization (By similarity).
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: IHFA_LEGPA
Sequence: MNALSKAIMAETLCDELKLNKPVAKEMVENFFEELRHALENGQHVKLSGFGNFTLRDKPQRPGRNPKTGEEIPVEARRVVTFKPGLKLKTKIEKIGK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CH60_MARN8
Sequence: MAAKDVKFGDSARKRMVAGVNILADAVKVTLGPKGRNVVLEKSFGAPTVTKDGVSVAKEIELKDKFENMGAQMVKEVASQANETAGDGTTTATVLAQSIVNEGIKAVTAGMNPMDLKRGIDKGTAEAVKAIREMAKPCDDSRMIAQVGTISANGDETIGKIIADAMEKVGKEGVITVEEGRGLEDELDVVEGMQFDRGFLSPYFINNQDNMSAELEDPYILLVDKKISNIRELLPVLEAVAKAGKPLQIIAEDIEGEALATLVVNNMRGIVKVNAVKAPGFGDRRKEMLQDIAILTGGTVISEEVGLTLENTTLDDLGTAKRVNVTKENTTIIGGAGAEADISARVEQIRKQIEDSSSDYDKEKLQERVAKLAGGVAVIKVGAGSEVEMKEKKARVEDALHSTRAAVEEGIVAGGGVTLIRAIAALDKVDAINDEQKAGVNILRRAMEAPLRQIVFNAGGESSVVVAKVKEGEGSFGFNAATEQYGDMLEMGILDPAKVTRSSLQAAASVASLIITTEAMVADEPEDDKAGGGMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_CHLCH
Sequence: MRSDTIKSGFEKAPHRSLLKATGAIRSSSDYRKPFIGICNSYNELIPGHTHLQELGRIAKEAVREAGGVPFEFNTIGVCDGIAMGHIGMRYSLASRELIADSVETVAEAHRLDGLVCIPNCDKITPGMMMAALRINIPVIFVSGGPMKAGHTPEGKTVDLISVFEAVGQCSNGSITEGELQNIEEHACPGCGSCSGMFTANSMNCLSEALGFALPGNGTIVAEDPRRLELVKAASRRIVDLVENNVRPRDILTRQALLNAFALDFAMGGSTNTILHTLAIANEAGLSFDFSELNALSAKTPYICQVSPATMAVHIEDVDRAGGISAILKELSSIDGLLDLSAITVTGKTLGENIANAEVLDRSVIRSISDPYSATGGLAVLYGNLAPQGAVVKTGAVSPQMMQHSGPAKVYNAQDDAIKGIMEGDVKAGDVVVIRYEGPKGGPGMPEMLSPTSAIMGRGLGDSVALITDGRFSGGSRGACIGHVSPEAAERGPIAALQNGDIITIDIPARTMSVALSESTIKERLAQLPPFEPKIKRGYLARYAQLVTSANTGAILGHL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y2757_CERSK
Sequence: MLAVLSPAKRLAARPALDLPADLAPSEPRLQDQADALARVARDLTAADLRRLMHISEPLARLNVARFAEFHEARNAAVPAVALFDGDTYAGLEARTMDADALRWAQERICILSGLYGLLRPLDRIQPHRLEMGTRLATERGVTLYDFWGDRIAEALNTRAAETGARVLVNCASVEYFTAADRAALKLPVITPTFLEERNGERKIVSFWAKRARGAMARFIAENRLNDPADLRAFRAGGYAYEPDLSTDERPVFLRAG
What are the official names of this protein?
UPF0246 protein RSKD131_2757.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL19_ACIBT
Sequence: MSGKHPLVQAIENSQLKTDLPEFAPGDTVVVQVKVKEGDRERLQAFEGVVIAKKNRGLNSAFTVRKISSGVGVERVFQTHSPVVAKIEVKRRGDVRRAKLYYLRDLSGKAARIREKLPARKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: NDK_PROMA
Sequence: MSVERTFLAIKPDGVQRGLVGEILGRFERKGFKLVGLKQLIPSKELAEKHYGVHKERPFFTGLVGFITSGPVVAMVWEGDGVILSARKLIGATKPLEAEPGTIRGDLGINIGRNVIHGSDGPETASFEIDLWFNSSELNNWNPSDQKWRVE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_ERWT9
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTRKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRTEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CHER_SALTY
Sequence: MTSSLPSGQTSVLLQMTQRLALSDAHFRRICQLIYQRAGIVLADHKRDMVYNRLVRRLRALGLDDFGRYLSMLEANQNSAEWQAFINALTTNLTAFFREAHHFPILAEHARRRHGEYRVWSAAASTGEEPYSIAITLADALGMAPGRWKVFASDIDTEVLEKARSGIYRLSELKTLSPQQLQRYFMRGTGPHEGLVRVRQELANYVEFSSVNLLEKQYNVPGPFDAIFCRNVMIYFDKTTQEDILRRFVPLLKPDGLLFAGHSENFSNLVREFSLRGQTVYALSKDKA
What is the function of this protein?
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
What are the official names of this protein?
Chemotaxis protein methyltransferase.
Protein: TAF11_YEAST
Sequence: MTEPQGPLDTIPKVNYPPILTIANYFSTKQMIDQVISEDQDYVTWKLQNLRTGGTSINNQLNKYPKYKYQKTRINQQDPDSINKVPENLIFPQDILQQQTQNSNYEDTNTNEDENEKLAQDEQFKLLVTNLDKDQTNRFEVFHRTSLNKTQVKKLASTVANQTISENIRVFLQAVGKIYAGEIIELAMIVKNKWLTSQMCIEFDKRTKIGYKLKKYLKKLTFSIIENQQYKQDYQSDSVPEDEPDFYFDDEEVDKRETTLGNSLLQSKSLQQSDHNSQDLKLQLIEQYNKLVLQFNKLDVSIEKYNNSPLLPEHIREAWRLYRLQSDTLPNAYWRTQGEGQGSMFR
What is the function of this protein?
Functions as a component of the DNA-binding general transcription factor complex TFIID.  Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation.  TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 11, TAFII-40, TAFII40, TBP-associated factor 11, TBP-associated factor 40 kDa, P40.
What is the protein family that this protein belongs to?
Belongs to the TAF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GAL1_ACTSZ
Sequence: MHPKSQSKQLFRQKYQKSPTLNVYAPGRVNIIGEHTDYNDGFVMPCAINYGTAISGAKRDDHRFNVYAADLDEFDEFRLDQPIIPNPSKKWTGYVRGVVKFVQERCPEFRQGADLVISGDVPLSSGLSSSASLEVAVGKFCQLLGDLPLNNTDIALIGQKAENRFVGANCGNMDQLISALGQADHLLMIDCRSLETVPTPVPEDIAVMIVNSHVKHDLVTGEYNTRRQQCETAAKFFGVKALRDVSIEQFQKREAELTALDPDTAKRARHIVTENQRVLDAAYALNHSDISRLGELMNASHVSMRDDFEITTPEIDYLVELAQSVIGKSGGARMTGGGFGGCIVGLAPKDKVDAVRQIIAENYEKRTGLKESFYVCTASQGVHQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHEB5
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAAAEAGALTTAAIKWFIKQYKIDMSEAAQSEPEAYKSFNAFFTRALKPGIRPLDMDADIMVHPVDGAVSQLGPIKNGRIFQAKGHHYSSLTLLGDQAEDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARNVPGLFARNERVVAIFETELGPLAMVLVGATIVASIETVWAGTVTPPTGKQVFTWEYPTQGPDAITLDKGEEMGRFKLGSTVVMLFAKDAIATFAEGVEAEAVTRMGQAFANLKDVKQAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SODC1_SALT4
Sequence: MKYTILSLVAGALISCSAMAENTLTVKMNDALSSGTGENIGEITVSETPYGLLFTPHLNGLTPGIHGFHVHTNPSCMPGMKDGKEVPALMAGGHLDPEKTGKHLGPYNDKGHLGDLPGLVVNADGTATYPLLAPRLKSLSELKGHSLMIHKGGDNYSDKPAPLGGGGARFACGVIEK
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn] 1, sodCI.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PANC_XYLFA
Sequence: MIETVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFRRYPRTPEADMRGLEHVGCDVLWLPSVETMYPLGTERTVRLFVPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQERPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQVDYAVIRLSDLGEPIDGTVISPGIALVAARLGNTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR41_MOUSE
Sequence: MLRWLIGGGREPQGLAEKAALQTIGEDQGQNPYTELLVLEAHRDIVRFLVRLDDFRFASAGDDGIIVVWNAQTGEKLLELRGHTQKITAVIAFPPLDSCEASSQLLLTASADRTVGVWDCDTGRQIQRVTCFQSTVKCLTVLQRLDIWLSGGSDLGVWNRKLDLLCKTSHLSDTGISALVEIPGNCVAAAVGRELIIFRLVTPTEELPEWDIIEVKRLLDHQDNILSLANINDTGFVTGSHVGELLIWDALDWTVQACERTFWSPTAQLDAQQEIKLFQKQNDISINHFTCDEENIFAAVGRGLYVYNLQLKRVIACQKTAHDSNILHIDKLPNRQLISCSEDGAVRMWEVREKQQLAAEPVPTGFFNMWGFGRVNKQASQPVKKQEENVTTCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGVRSLKLFQKLEENGDLYPESP
What is the function of this protein?
Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy.  The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation.  As part of the C9orf72-SMCR8 complex, stimulates RAB8A and RAB11A GTPase activity in vitro, however WDR42 is shown not be an essential complex component for this function (By similarity).  The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ULK1/ATG1 kinase complex and inhibiting its protein kinase activity.
What are the official names of this protein?
WD repeat-containing protein 41.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_ALCBS
Sequence: MSSIEERVNKIIVEQLGVKPEDVKSEASFVEDLGADSLDTVELVMALEEEFETEIPDEEAEKISTVQSAVDYIKAHS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_PHOPR
Sequence: MIDTSTITNPQTLPVEAITQENLRNTLEQFAEQQKQQFIQHRPVTDLVLSRSTFIDKLLIRLWEHYEVNQYPDIALVAVGGYGRGELHPLSDVDILILSAQPLSDETGRIVSKFLTFLWDLRLEVGHSVRTIDDCIEIGNDDLTVATNLTEARILCGSEDVFQCLQERINAGNFWPSEDFYRAKLEEQKTRHARYHDTTYNLEPDIKSSPGGLRDIHTLSWVARRHFGATSLLEMSRFGFLTDAEYRELVECQDSLWRIRFALHIELRRYDNRLTFSHQPSVAENLGYTGEGNRGVEMMMKEFYRTLRRVLELNKMLLQLFDQAILDNGKTVETIQLSDDFQIRGHLIEATKPALFQARPETILDMFLHIAQNGDIEGIAAPTLRQLRTARQRLNVFLVDIPEAREKFMELVRQPNTLQKAFRLMHRHGVLSAYLPQWSQIVGQMQFDLFHVYTVDEHSVRLIKNLNKFNDPENRERHPICCEVYPRIIKKELLTIAAIFHDIAKGRGGDHSELGAIEARKFCIQHGLSRPETNLIAWLVQKHLLMSVTAQRRDIYDPEVVAEFAKEVRDEERLDYLICLTVADICATNQELWNSWKRTLLAELYYSTQKALRRGLENTPDVRDRIRHNQQLSSAILRGKGFAPREIEVLWKRFKADYFLRHTHKQLAWHAEALLTHDHDKPLILLSKKATRGGTEVFVYNKDKAKLFAIVVSELDKKNLSVHDAQIMNSKDGYTLDTFMVLDPSGKTIPENRHNTIRRALVNALTKMKSERKNKRAPRKLMHFNVKTQVDFLPTKTGKKTTMELIALDTPGLLARIGAVFAKQKVSLQAAKITTIGERAEDFFILVNEHGSPLTEEHQQALKEALIIKLTPQD
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: YO029_YEAST
Sequence: MKPVTCCNQKNNIMPSLVPVCCSEKKIESDAKKSISKCCGDKEIYDSENRPITKEDGSWIPGSCKQCRSDPHSRNFCQSLSNKCSSSSFSSNSALSPDLNEQQTDVNYNSIKLPEICSCKNAQMNAASDAKRYLPISYTYQKIRQHMQKNKSIQEQLNPEDSTSISSALENIASGLHVRGQKVELQSIKDALHKMDKNVLE
What are the official names of this protein?
Uncharacterized protein YOL029C.
Protein: FOLD_HALWD
Sequence: MRFKYVASKYSCVTQTQTQLIDGTEVAASIRSDLISSVTRIVNTGTTPQLATVLMNDDPASQTYVSMKHDDCEEVGIATRDITIDPEAPAAELFDTVDELNADSSVHGILVQMPLPDHVDEREVLRRIDPKKDVDGFHPENVGRLVAGQPRYKPCTPHGIQKLLIAADIETEGANAVVIGRSNIVGKPMANLLIQKADAGNATVTTCHSRTNNLASKTRDADIIIAAAGVPEMIDGDMISTGTVVIDVGINRVETENGSELVGDVEFESAAKKADAITPVPGGVGPMTRAMLLWNTVKATAIATDTSIELP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GUF1_LODEL
Sequence: MLRPWFCFRSCVSLLSNRRQYGFRYLATAEPSKSEKPAKPVKPAKPMSVQEKKMRLGQDQFRKELEERISKIPIQNYRNFSIVAHVDHGKSTLSDRLLELTGVIEPGSKSQVLDKLDVERERGITVKAQTVSMLYTEPASGQDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFFLAYSMDLKLIPIINKIDLDLANIPRAMEQVETTFELDPADCIPVSAKTGLNVEKIIPSIIKNIPAPVGDESRPLKALLVDSWHDPYVGVVMLVHVVDGKLKKGTKLLSAHTNKTYDVKEVGIMYPDRTPMEYIKAGQVAYVIPGMKNPREALVGDTFFQLGKSEGLDPLPGFEEPQPMVFVGAFPSEGKDFSIMDDSIQNLVLNDRSVHLEKETSNALGSGWRLGFLGSLHASVFKERLEKEYGAKIILTAPTVPYKIVFKNGDEKIITNPDEFPDNKMHNLVSHYMEPYVETIMTLPNEYVGTVMQLCLSNRGEQKEVEYLNTGQTLLRYDIPMAQLVEDFFGKLKGCTKGYASLDYEDAGYRKSDIVKMELCVNGEPQDALTTIVHKSIAQAKGKEYVTRFKKFLRYQLFEVAIQARVNNKVIARETIKAKRKDVTQKLHAADISRYKKLLERQKEGKKQMKAVGRINIGNDAYQAFLRRDN
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DSTOR_RHOCA
Sequence: MTKFSGNELRAELYRRAFLSYSVAPGALGMFGRSLLAKGARAEALANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPTPMLEGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPQGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGADHVTPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLMGETDSTPKTAEWASDISGVPAETIKELARLFISKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALSGITDGGAATKGPEWLAASGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFIVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGKEFTEGKDEMGWIKSFYDDAAKQGKAGGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE
What is the function of this protein?
Catalyzes the reduction of dimethyl sulfoxide (DMSO) and trimethylamine N-oxide (TMAO) to dimethyl sulfide (DMS) and trimethylamine, respectively.  The terminal DMSO reductase can also use various sulfoxides and N-oxide compounds as terminal electron acceptor in addition to DMSO and TMAO.
What are the official names of this protein?
Dimethyl sulfoxide/trimethylamine N-oxide reductase, DMSO reductase, DMSOR, Me2SO reductase, TMAOR.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CLPX_STRM5
Sequence: MSEDRQGRSTDTGKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQNRAKRTLAVAVYNHYKRIESRQKNDEVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQARSTDVGSIGFGAKVKSAERKQEVGKVLAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFEMENVELEFRPDALSAIARKALKRKTGARGLRTIVESVLLDTMYDLPSQENVSKVVVDESVIEHKSEPYLIYQTPAAPEQKAAGAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.