PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_SALEP
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: FABZ_METFK
Sequence: MDIHEILNYLPHRYPFVLVDRVLSLELNKEIVAVKNVTINEPFFPGHFPYHPVMPGVLIVEALAQAAAILSFKTMGTKPNDKSVYYFAGMDNVRFKKPVSPGDQLILKVSIDRILRGIWRYKGEALVDGAVVAEAEMMCILKAID
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_LACDB
Sequence: MKEIDKYAGKNILVLGLGRSGFAVSKLLLKLGARLTLNDKADLAADPKAKQLADLGVRVIGGSHPVDLFDEEKFDYLVKNPGIPYENPMVAKASEKGVPIITEPEVALSASESPYVCVTGSNGKTTTVMLTQQIMDHYLQKQGHHAYAVGNIGWPISEVVLNQAGPDDLLVVEMSSFQLMGVTDIEPKVAAIVDIYNNVHLDYHKTFDNYVDAKLNVGRFQKTSDYFLANFDQKDILAREEKATKAKILTFSENDPVADFYIGQDYLMHGEEKMMKIADIKLPGIHNLQNSLVAIGISSLMGAGKDDIAAVLSTFTGAEHRLQYVTTLDGVKVYNDSKSTNIEAATVAIQSFKQPEVLLAGGLDRGFVFDSLVDLFKKHVKAIVTYGETRYLLADAARKAGIKTIVVVDNLHEGVKAASKLAEAGDVLLFSPACASWDQFKTFEERGEYFVKYVKELEEK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3295_LEPIC
Sequence: MNNKIKLIKEDITQLEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVITTAGRLNAKFIIHTVGPIWSGGNKNEDELLSNAYKNSLLLAKNHSLKTIAFPNISTGIYHFPKERAAKIAIQSVTKFLKQDNQIQTVFFVCFDFENLEIYNKLLQTYK
What are the official names of this protein?
Macro domain-containing protein LIC_13295.
Protein: PYRC_THET8
Sequence: MILIRNVRLVDARGERGPADVLIGEGRILSLEGGEAKQVVDGTGCFLAPGFLDLHAHLREPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKAKALGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDAGLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRTFDPLFKVAPPLRGEEDREALLEGLLDGTLDAIATDHAPHTLAEKEKDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPLHLEEGAEASLVLLSPKERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEALK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: ALAXS_PYRHO
Sequence: MYSIEVRTHSALHVVKGAVVKVLGSEAKWTYSTYVKGNKGVLIVKFDRKPSDEEIREIERLANEKVKENAPIKIYELPREEAEKMFGEDMYDLFPVPEDVRILKVVVIEDWNVNACNKEHTKTTGEIGPIKIRKVRFRKSKGLLEIHFELLELENPS
What is the function of this protein?
Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala).  Has little activity against Gly-tRNA(Ala).
What are the official names of this protein?
Alanyl-tRNA editing protein AlaX-S, AlaX-S, Alanyl-tRNA deacylase AlaX-S, PhoAlaX.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Editing domain AlaX-S subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WRK35_ARATH
Sequence: MDNFQGDLTDVVRGIGSGHVSPSPGPPEGPSPSSMSPPPTSDLHVEFPSAATSASCLANPFGDPFVSMKDPLIHLPASYISGAGDNKSNKSFAIFPKIFEDDHIKSQCSVFPRIKISQSNNIHDASTCNSPAITVSSAAVAASPWGMINVNTTNSPRNCLLVDNNNNTSSCSQVQISSSPRNLGIKRRKSQAKKVVCIPAPAAMNSRSSGEVVPSDLWAWRKYGQKPIKGSPYPRGYYRCSSSKGCSARKQVERSRTDPNMLVITYTSEHNHPWPTQRNALAGSTRSSSSSSLNPSSKSSTAAATTSPSSRVFQNNSSKDEPNNSNLPSSSTHPPFDAAAIKEENVEERQEKMEFDYNDVENTYRPELLQEFQHQPEDFFADLDELEGDSLTMLLSHSSGGGNMENKTTIPDVFSDFFDDDESSRSL
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 35, WRKY DNA-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-e family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYE_ECOLC
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMSQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BACC0
Sequence: MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEALGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVSKIPVKDYLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELLDAAEQGIFQLIDIQKEALGDIVSHIE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PHKG2_RAT
Sequence: MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQPWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPRPFPIIATDLEGDSSAITEDEVTLVRS
What is the function of this protein?
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase.  May regulate glycogeneolysis in the testis.  In vitro, phosphorylates PYGM.
What are the official names of this protein?
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, PHK-gamma-LT, PHK-gamma-T, Phosphorylase kinase subunit gamma-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: Y2961_MYCUA
Sequence: MTTSEYGSRRSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDEYAKYFIAASGDAYLNDQLAHPPTSVDETAFPRLYGVQTRFFDDFFRSAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLAQVLEFKARVLQRHGVEPKARRNAVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLPYLTADAQDALFARIDDLCAPGSRIATGALGSRLDHDQLVALEQTHPGVNLFGDVNFSALTYDDKTNPAQWLAARGWVVEPVRNTLELEAGYGMTPPAVDVRLDAIMHSEYIVATKP
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_2961.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: SEN54_MOUSE
Sequence: MEPEPEPGSVEVPAGRVLSASELRAARSRSQKLPQRSHGPKDFLPDGSEAQAERLRLCRQELWQLLAEERVERLGSLVAAEWKPEEGFVELTSPAGKFWQTMGYSEEGRQRLHPEEALYLLECGSIQLFYQDLPLSIQEAYQLLLTEDTLSFLQYQVFSHLKRLGYVVRRFQLSSVVSPYERQLNLDGYAQCLEDGSGKRKRSSSCRSVNKKPKVLQNSLPPVSLAASSSPACDQSSQYPEEKSQDSSPRQGSELPLQFLGSSEPCSDLAREDVGCDRESHKIENGAKGTPKLRWNFEQISFPNMASDSRHTFLPAPAPELLPANVIGRGTDAESWCQKLNQRREKLSRRDREQQAVVQQFREDVNADPEVRGCSSWQEYKELLQRRQTQKSQPRPPHLWGQSVTPLLDPDKADCPAAVLQHISVLQTTHLADGGYRLLEKSGGLQISFDVYQADAVATFRKNSPGKPYVRMCISGFDDPVPDLCSLKCLTYQSGDVPLIFALVDHGDISFYSFRDFTLPRDLGH
What is the function of this protein?
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen54, tRNA-intron endonuclease Sen54.
What is the protein family that this protein belongs to?
Belongs to the SEN54 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=May be transiently localized in the nucleolus.
Protein: RSMF_SALTI
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEAVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTSLKGREALNVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPLGLAKRIGARIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_THEGJ
Sequence: MKVKKHRFPGVYIVIDDDGSEKIATKNLVPGQRVYGERVIKFEGEEYRIWNPSRSKLGAAILNGLKNFPIKPGSTVLYLGIASGTTASHVSDIVGWEGKIFGVEFSPRVLRELVPIVEERRNIVPILGDATKPEGYRALVPKVDVIFEDVAQPTQAKILIDNAKVFLKSGGYGMISVKSRSIDVTKEPEEVFKEVERELASYFEVVERLSLEPYEKDHALFVVRKP
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: RUVB_RICM5
Sequence: MISHYIRFKIMTNILLSPEKSENDQELPIRPSYLQEFVGQQQIKENLSVFIKAAKSRNEHLDHTLFYGPPGLGKTTLAKIISNEIGGNFKSTSGPAILKVADLAAILTNLERNDVLFIDEIHRLNTAVEEVLYPAMEDFELDIIIGEGSAARSVKITLPKFTLIGATTRLGLLSNPLRDRFGIPMRLNFYNTEELKKVLNRASKLLDIDLTDSGSEEIAKRSRGTPRIALRLLRRIRDFAAVDGKSRVDKEISDFGLNRLEVDRIGLDSNDYRYLKFIADNYNGGPVGIETIAAALSEQRDALEETIEPYLIQIGLLQRTPRGRVITIAAFEHLKMPVPNQSHHQFNIFNEHE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LFTR_PSEA6
Sequence: MIELFQLDKSLHFPPPAHALTDPPGLLAFGGDLSVNRLLHAYQQGIFPWFSANEPILWWSPDPRGILPLDNFSVSKSLRKFIRKTPLRVTVNRRFDEVIYACAKVKRQSSGTWITDDMINAYIELHRCGGAHSIEVWDDEELVGGLYGVTPGNVFCGESMFHYATNASKLAMFYLVELLRLNGCEFIDCQLQNDHLASLGCIEMPRAEFLNRLKEAVKHPMDQSLWLPRELTQP
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_SHEB5
Sequence: MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYANAPAMQVAHRSHVINMLDANALRAVIELEKPHLVIPEIEAIATQTLVDMEAEGVNIIPTARATKLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAISEIGVPCVVKPVMSSSGKGQSVIRDIALSHKAWQYAQEGGRAGGGRVIVEGFIPFDYEITLLTISAVNGIHFCAPIGHRQEDGDYRESWQPQAMSDEVLAKSQAIASKVVEALGGYGLFGVELFVKGHEVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVILAEGTSSNIRYQGIAAALEAVNTQLRLFAKPDIDGRRRLGVALARDIDIDSAVSKALDSASKVKVIF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: BBLN_CTEID
Sequence: MSGPNGDPNISVDDGIIEDEDEFSEEEYAAIDSMLDQINSCLDDIEDRNDALNGKLHELLESNRQARKDFRQQLNDEEASPPPAEDPASRDTQTED
What is the function of this protein?
Essential for intermediate filament organization in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology.
What are the official names of this protein?
Bublin coiled-coil protein, UPF0184 protein C9orf16 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0184 (EST00098) family.
Protein: ACPH_PHOLL
Sequence: MNFLAHLHLATLADSSLLGNLMADFVRGNPEGQYSADVVAGIRMHRRVDVLTDTHPLVIQARHLFSNSYRRVAPITLDIIWDHFLSLNWDKLVPTYSLPAFIHHARSQIEPHLYYTPEKFQELNAFLWRQNWLIRYADLAFIADVLKGMARRHPRLSALSGSFQDIEQHYADFDALFWQFYPYMMEKAENKDFYCLPQ
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: RSMG_OENOB
Sequence: MNPDEFVTTLNNQSLPISNRKMVLFQTYLEFLLEYSKKVNLTAIKEPKDIWLKHFYDSLTPLLYLPDMNKKASLIDIGSGAGFPGVPLKIVNQKFQLTLLDSLQKRIAFLDQLIDKLNLKNVETVHGRAEDFAHNLNYREKYDFAIARAVSNTNTLLELLLPFVKVGGKIILMKTVHVESEIYGASKALEELGGRVSQSFSFELPNDDPRVLITIDKISSTKKRYPRKAGVPEKSPIGGKHD
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERB_SERMA
Sequence: MKLAPYILERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQATSTEYDKDGNIIGYGLTLRETSYVFEIDDRRLYAWCALDTLIFPALIGRTARVSSHCAATGAPVSLTVSPSEIQAVEPAGMAVSLVLPQEAADVRQSFCCHVHFFASVPTAEDWASKHQGLEGLAIVSVHEAFGLGQEFNRHLLQTMSSRTP
What is the function of this protein?
Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate.  One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
What are the official names of this protein?
Alkylmercury lyase, Organomercurial lyase.
What is the protein family that this protein belongs to?
Belongs to the MerB family.
Protein: IPYR_PSEAO
Sequence: MDLSRIPPQPKAGILNVLIEIPAGSKNKYEFDKDLNAFALDRVLYSSVQYPYDYGFVPITNNLADDGDPLDGMVIMVPPTFPGVATARPIGMLQMVDGGDRDEKFLCVPAKDPRYTYVKSANDLAGHRLDEIFEFFRSYKNLFKKPTEFFGWKGDVAGLPLVEECVKNYYKTYCKNDHGK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_ACIBT
Sequence: MTVQIITIDGPSGSGKGTLAAKLAAYYQFHLLDSGALYRLLGLSLHKHDLLEKLDSHLDECVNYARQLNIKFETSAEGTLVFLDGEDVTQTIRTERVGEYASKVAAIPELRQALFERQRAFAQTPGLVADGRDMATSIFPEANAKIYLTASAESRAERRVKQLQGMGLDAKINDILANIQARDKRDMEREVAPLKPAADAYIIDSSELTIDQVFKLMVDYVNSRTVSN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_CAMJR
Sequence: MSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGGCEFVDEIETLAIERCKKLFNCKFANVQPNSGSQANQGVYAALINPGDKILGMDLSHGGHLTHGAKVSSSGKMYESCFYGVELDGRIDYEKVREIAKKEKPKLIVCGASAYARVIDFAKFREIADEVGAYLFADIAHIAGLVVAGEHPSPFPHAHVVSSTTHKTLRGPRGGIIMTNDEELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIADILDDVNNEKLQKNIKQELKKLASNFIIYERAMF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_BACFR
Sequence: MSENIRVSEVSDILRQQLEGIETKVQLDEIGTVLQVSDGVVRIYGLRNAEANELLEFDNGIKAIVMNLEEDNVGAVLLGPTDKIKEGFTVKRTKRIASIRVGESMLGRVIDPLGEPLDGKGLIGGELYEMPLERKAPGVIYRQPVNQPLQTGLKAVDAMIPIGRGQRELIIGDRQTGKTSIAIDTIINQRSNYEAGDPVYCIYVAIGQKGSTVASIVNTLRQYGAMDYTIVVAATAGDPAALQYFAPFAGAAIGEYFRDTGRHALVVYDDLSKQAVSYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQEEVAREMNDLPESLKGKVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDTDLFNQGNRPAINVGISVSRVGGNAQIKAMKKVAGTLKIDQAQYRELEAFSKFSGDMDPVTALTIDKGQKNARLLVQPQYSPMPVEKQIAILYCGIHGLLRNVPLDKVEDFEAAFLNTLALDHQADVLDVLKTGVINDEVTKAIEETAAMVAKQYS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DSBI_SALCH
Sequence: MDFIKGLWRDLRARPVDTLVRWQEQRFLWLLMAIAMGGLIILAHSFFQIYLYMAPCEQCVYIRYAMFVMVIGGVIAAINPKNIVLKLIGCIAAFYGSIMGIKFSIKLNGIHHAVHNADPDSLFGVQGCSTDPTFPFNLPLAEWAPEWFKPTGDCGYDAPIVPDGVTLSSVQQWFVDLYQQSEGWYLLPPWHFMNMAQACMLAFGLCLILLLVMSGAWALKLARGK
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.
What are the official names of this protein?
Protein-disulfide oxidoreductase DsbI.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. DsbI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OLEE_STRAT
Sequence: MNLLVTGAAGFIGSRYVHHLLEATRRGREPAPVITVLDKLTYAGVLGNVPDDPAVTFVRGDIADAPLVDSLMAEADQVVHFAAETHVDRSITSPGTFVRTNVLGTQVLLDAALRHGVGPFVHVSTDEVYGSIEHGSWPEHQPLCPNSPYSASKASSDLLALSYHRTHGLDVRVTRCSNNYGPHQFPEKIVPLFVTNLLDGLRVPLYGDGLNVREWLHVDDHCLGVDLVRTQGRPGEVYHIGGGTELTNRDLTGLLLDAFGVGWDVVDPVADRKGHDRRYALDCAKAADELGYRPRRDFAEGIARTIDWYRDNRAWWEPLKKRPAGPAAPPRGSGP
What is the function of this protein?
Involved in the biosynthesis of the two 2,6-deoxysugars, dTDP-L-oleandrose and dTDP-D-desosamine, attached to the macrolactone ring oleandolide to produce the aglycone antibiotic oleandomycin (PubMed:10770761).  Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction (By similarity).
What are the official names of this protein?
dTDP-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: ORN_TROWT
Sequence: MCVAPTPSHLVWVDCEMTGLNPERDELLEVAVVVTDKDLLPLDEGVNVVVSPSSEALGAMDNYVARMHRVSGLLDELSNGVPVSEAQAMVKEYITKHVKTGGIMSGNSIATDRLFITRYMPDVHAILHYRMIDVSSIKELAVRWAPEIYSGAPNKKGGHRAMADVLESIAELAYYREHFLTGTA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.