PharMolix/UniProtQA huggingface dataset:
Protein: ABH15_HUMAN
Sequence: MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLPGAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVAPGPELAREYLQLADDGLVALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIALSRYATALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR
What are the official names of this protein?
Protein ABHD15, Alpha/beta hydrolase domain-containing protein 15, Abhydrolase domain-containing protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MINE_SALTI
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL30_BORPD
Sequence: MAQKQIKVTLVRSVIGTKQSHRDTVRGLGLRRINSSRVLVDTPEVRGMIRKVDYLVSVSEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RF1_HELPG
Sequence: MSILAEKLSSILKRYDELTALLSSAEVISDIKKLTELSKEQSSIEEISIASKEYLSVLEDIKENKELLEDKELSELAKEELKILETKKSDLETAIKQLLIPKDPNDDKNIYLELRAGTGGDEAGIFVGDLFKAYCRYADLKKWKVEIVSSSENSVGGYKEIIALIKGKGVYSRLKFEAGTHRVQRVPETESQGRIHTSAITVAIMPEVDDVEVSINPSDLKIEVFRAGGHGGQCVNTTDSAVRITHLPTNISVSMQDEKSQHKNKDKALKILKARLYEKQIEEQQLANAKDRKEQVGSGDRSERIRTYNYPQNRLSEHRINLTLYSLEEIMLSGNLDEVINPLIAHAQSQFE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 2SS4_BRANA
Sequence: MANKLFLVSATLAFFFLLTNASIYRTIVEVDEDDATNPAGPFRIPKCRKEFQQAQHLKACQQWLHKQAMQSGSGPSWTLDGEFDFEDDMENPQGPQQRPPLLQQCCNELHQEEPLCVCPTLKGASKAVKQQVRQQQGQQGQQLQQVISRIYQTATHLPKVCNIPQVSVCPFQKTMPGPSY
What is the function of this protein?
The small, basic, water-soluble napins are one of the two major kinds of storage proteins synthesized in the seed during its maturation.
What are the official names of this protein?
Napin, 1.7S seed storage protein.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: DNAJ2_CORDI
Sequence: MAAKNEWAEKDYYADLGVSSSATEAEIKKAYRKLARENHPDSHPGDAAAEERFKKVAEAYDVVGDETKRKEYDEFRSMIASGGFGGAGFPGGFRTQEGFDFDLGDIFGSGAGRGHAPQGGFGDIFGGIFNRGGGARNAARPTRGSDVETEITLEFREAAKGTTIPLQLTGDAPCHTCHGSGSRSGAPTTCTECNGTGFTSENKGAFGFSAPCTQCGGTGKMISDPCPDCSGTGTQRRTRSITVRIPAGVVDGQKVRLAGQGEAGPNGLPAGDLYVTVHVKNDRVFTRSGDDLEVTVPVSYAELALGDTISVPTLDLPVRVRIPSGTPNGRVLRVRGKGVPKRGGSAGDLLVKVEVTVPSSLDAASASALRAYVQAERDAGFDPRAGWAGK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_MARN8
Sequence: MPKASEIKKNQAVEYEGRVYFVKDIERSVPQGRAGGSLYRMRMYDVVTNQKLDETFKDSDMLNLADLVRREATFSYADGDEYVFMDTEDFTQYMLNRSAIEDELLFITEDTQGVMVILVSENPVAIDLPPTVELTIEETDPSIKGGSATARTKPARLTTGLVVQVPEHISTGDRIRVNVEERKFLSRA
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: FETP_KLEP7
Sequence: MSRTIFCTFLQREADGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLSMMNPEHRKLLEQEMVQFLFEGKDVHIEGYTPPEKQ
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CHS7_PICMA
Sequence: MAGGLMADLEAFRKAQRADGPATILAIGTATPPNAVDQSTYPDYYFKITNSEHMTELKEKFQRMCDKSAIKKRYMYLTDEILKENPNVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQLTKLLGLRPSVKRVMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAALIVGADPIPQVEKPCFELMWTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQQFGISDWNQLFWIAHPGGPAILDQVEAKLNLDPKKLRATRQVLSEYGNMSSACVHFILDEMRKSSNEKGCSTTGEGLDVGVLFGFGPGLTVETVVLKSVPLQ
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 7, Naregenin-chalcone synthase 7.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: AOC3_BOVIN
Sequence: MNQKTTLVLLALAVITIFALVCVLIAGRGGDGGEASQPHYCPSGTPSVQPWTHPGQNQLFADLSREELTAVMSFLTQKLGPDLVDAAQARPSDNCIFSVELQLPPKAAALAHLDRRSPPPAREALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYYRRPVLLREYLDIDQMIFNRELPQAAGVLHHCCSYKQGGGNLVTMTTAPRGLQSGDRATWFGLYYNISGAGYYLHPVGLELLVDHKALDPAQWTIQKVFFQGRYYESLAQLEEQFEAGRVNVVVIPNNGTGGSWSLKSQVPPGPTPPLQFHPQGTRFSVQGSRVTSSLWTFSFGLGAFSGPRIFDIRFQGERLAYEISLQEAVAIYGGNTPAAMLTRYMDGCFGMGKFATPLTRGVDCPYLATYVDWHFLLESQAPRTLHDAFCVFEQNKGLPLRRHHSDFISQYFGGVVETVLVFRSVSTLLNYDYVWDMVFHPNGAIEVKFHATGYISSAFFFGTAQKYGNQVRENTLGTVHTHSAHYKVDLDVGGLENWVWAEDMAFVPTTVPWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHPRGYRIQTVSFAGRPLPQNSSTERAISWGRYQLAVTQRKETEPSSSSVFNQNDPWTPTVDFADFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSINSADSIYFQKHQDAGSCEVNSLACLPKDPACAPDLPAFSHGGFFTN
What is the function of this protein?
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion.  Has a monoamine oxidase activity (By similarity).
What are the official names of this protein?
Membrane primary amine oxidase, Copper amine oxidase, Semicarbazide-sensitive amine oxidase, SSAO, Vascular adhesion protein 1, VAP-1.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SOCS1_HUMAN
Sequence: MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI
What is the function of this protein?
Essential negative regulator of type I and type II interferon (IFN) signaling, as well as that of other cytokines, including IL2, IL4, IL6 and leukemia inhibitory factor (LIF) (PubMed:32499645, PubMed:33087723).  Downregulates cytokine signaling by inhibiting the JAK/STAT signaling pathway.  Acts by binding to JAK proteins and to IFNGR1 and inhibiting their kinase activity.  In vitro, suppresses Tec protein-tyrosine activity (PubMed:9341160).  Regulates IFN-gamma (IFNG)-mediated sensory neuron survival (By similarity).  Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:11278610, PubMed:11313480).
What are the official names of this protein?
Suppressor of cytokine signaling 1, SOCS-1, JAK-binding protein, JAB, STAT-induced STAT inhibitor 1, SSI-1, Tec-interacting protein 3, TIP-3.
What is the protein family that this protein belongs to?
Belongs to the SOCS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasmic vesicle. Note=Detected in perinuclear cytoplasmic vesicles upon interaction with FGFR3.
Protein: GRC3_CRYNJ
Sequence: MSALAARRATAAAASPKPEQPESSIEEVSVSGALTLPSPKRRKTRQTSPKPRSKARYSDDVPTSRQFFQATESLAEQRTGRFSPSAPDSDGGTSSSSVGDSDEDMAQEDEFEDRREVDGERDQRKVSVAANMSSSGPFKSLDLMPVDITSQFNPKDNVNFCRITEGQLASAEMNDGHPGPGVIVSLARNESLTIAGLFLLTPLQNTLSIYSTALSPSMSSFPVYAPTSHPLPVISPASTQAPGKESDKTLLLIRENRCGIDGLRNGAVPGFSNIWLEDNGPWGLRGVHPVVGSFPVPVYPYCTPPSWSHAISSLSSSDVNLQTPFVGLVKGPKRSGKSTFARALLNNLLRRFRKVAWLECDLGQGEFGSGAVVGLWILDKPALGPPFTHPLLPSRSHYLGTYTPLTCPDEYLVAIRHLIEHYKYELQYTSEYSALHTTVHDKISTHVPLVINTQGWMKGLGEELLNVIESMAQPTRVFSFESQSEEVYSGQGWTSTPPWQATQLPYDPAYPTTEPVETEVTQTYSLETAPVSALQARYTPADLRVLSAITYFHASLHPTQSVPVTWDISSPLVCTIPWEVELGIGKALEKVYLIGEGSEGVLEEDLPIALNGAIVALAEMLGSYEDEPTVYEQGRSPPPTDLVNILGLAVIRSLSSGNSVNPGLKLQLLTPLPPSYLSRARILIKSGALELPLPGMIDWRRGGINEEGMLGKGWEEIPFLDVGGLDVIGGERRRFRKNIMRKGM
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase GRC3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL9_METFK
Sequence: MQVILLEKVVNLGNLGDIVKVKDGYGRNFLIPQGKAKRATEANKAEFEARRAELEKQQAEQLAAAQKRGEKLAGFMLQVTQKAGVDGRLFGSVTNGDIAEALTAQGFEVSKSEVRLPEGPLKAIGDYQVHIALHHDVVVEITVSVLGE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: UVRC_HALSA
Sequence: MNGDEVRARASELPAEPGVYQFVARDPDGTADGERVLYVGKAVDIRDRVRSYGDPRSERIAGMVARADDVTVAVTDTETQALLLEANLVKRHQPRYNVRLKDDKSYPLVQVTSHREAPRIEVTRDPDPGAAAFGPYTDKGDVETVVKAVRSVYGLRGCSEHKYRDRERPCLDYEMGLCAAPCTGAISEREYREAVESATRFFEGETGALADPLRREMAAAAQAEAFERAANLRDRLAVVEGFHEGGGAAVAAGDADAGASTDVLGVAVEGDAATVARLHAEGGQLVERDQHRLEAPQGEDRVAAVLAAFLVQYYAERDLPERILLPEPHGDDEVAAWLDAADVAVGVPGAGREARLVELALKNAHRRAGGGDELGALADALGVRRPERIEGVDVSHAQGREVVGSNVCFVDGSAETADYRRKKLDEENDDYANMRRLVGWRAERAVDGRDDRPDPDVLLVDGGRGQLDAALDAVEAAGWDGPDAVIALAKDEEVVVTPDRTYDWGSDAPQLHVLQRVRDEAHRFAVAYHRTLRDDVTTALDGITGVGPELRARLLGRFGSVAGVRQASVKDLRDVAGVGEATAETIAKRL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_BORPA
Sequence: MLDREGYRPNVGIILVNGKNEVFWGKRIREHAWQFPQGGIKYGESPVQAMYRELHEEVGLKPEHVRILGRTRDWLRYNVPDHFVRREWRGHYKGQKQIWFLLRLVGRDSDVCLRATQHPEFDAWRWSQYWVPLDAVIEFKRDVYTQALNELAVILFRRHHETRYLRQRVHGPRSTDNPSSETDGHAHIAG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: HOFQ_ECOLI
Sequence: MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIARQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRLVSSE
What is the function of this protein?
Required for the use of extracellular DNA as a nutrient (PubMed:11591672).  Could be the porin responsible for transport of DNA across the outer membrane (PubMed:16707682).
What are the official names of this protein?
DNA utilization protein HofQ.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. PilQ subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: FADB_ALIFM
Sequence: MIYQGENLSVDYIEPGIAHLVFNAKGSVNKLNLATLQSVGEAIDALYSQKDLQGLLLSSDKSAFIVGADITEFLGLFDIPTEELSDWLHQANAIFNRLEDIPVPTLSAITGFALGGGCECVLATDFRLADETASIGLPETQLGIMPGWGGSVRLPRLIGADPAMEVITTGKPKRAKDALALGMIDGVVSRETLITDSVTMLKKAIGGQLDWQSRRTQKKAPLKLSPLEAAMSFNVAKGMIMKMAGKHYPAPMTAVKSIENSAFMDRDAALEVENKNFVALTQTDVAKSLVGIFLNDQLVKSKAKQAIKNSEPVTSAAVLGAGIMGGGIAYQSASKGVPVLMKDIAQQSLDLGMNEASKLLNKQLERGRLSGLKMAQVLSSITPSLNYASIENKDIVVEAVVENPKIKAAVLAEVENEVNEHAILASNTSTIPISLLAKSLKRPENFCGMHFFNPVHRMPLVEVIRGEKTSQQTIDRVVAYASQMGKTPIVVNDCPGFFVNRVLFPYFAGFSLLLRDGGDYQQIDKVMEKEFGWPMGPAYLLDVVGIDTAHHAQAVMAQGFPERMAKNGRDVIDAMFESDRYGQKNGSGFYAYSIDRKGKPKKNIDESTAGIIATVTNTTQPYTSEQISARMMIPMINEVIRCLDEGIIASPAEADMALVYGLGFPPFKGGVFRYLDAIGLTTYLDMAKEFEHLGAVYQVPESIKQKAADGECYYPAPQSLSAPSA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: COX7C_BOVIN
Sequence: MLGQSIRRFTTSVVRRSHYEEGPGKNIPFSVENKWRLLAMMTLFFGSGFAAPFFIVRHQLLKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIIA, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATP6_SERP5
Sequence: MSASGENGTAKDYISHHLNNLQLDLRTFQLVEPHSGTPTFWTLNIDSLFFSVVLGALFLFIFKKVANTATSGVPGKLQTAVELIMGFVDSSVRDMYHGKSKVIAPLALTVFVWVFLMNMMDLLPIDLLPFIGEHVFGLPALRVVPTADVSITLSMALGVFILILFYSIKMKGVGGFVKELTMQPFNHPLFIPINLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWLLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDUI_YERPN
Sequence: MQVRQSIHSDHAKQLDTAGLRREFLIEKIFAADDYTMTYSHIDRIIVGGILPVSKAVSIGNEVGKQLGVSYFLERRELGAINIGGPGLIVVDGQTYDIGNEEALYVGKGAKEVKFSSIDRANPAKFYYNSAPAHTTYPNKKITLAEASPQTLGDDATSNRRTINKYIVPDVLPTCQLSMGLTKLAPGSLWNTMPCHTHERRMEVYFYFDMDEETAVFHMMGQPQETRHLLVHNEQAVISPSWSIHSGVGTKRYTFIWGMVGENQVFGDMDHIAVSELR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: SOJ_TREPA
Sequence: MGKTLVFVNQKGGVGKTTSAINLGAYLALAGKKTLLVDFDPQGNMSSGLGLARGLTVYDLLAGKAHINSVLRTTPVHNLFAIPASIDLSGATVELVDEQDRELYLKKILAEVKDTYDFILIDCPPSLGILTLNGLAAANEVFIPLQCEYFALEGLTLLLQTVKRVQSGLNTALSIGGIFFTMYDTRTKLAQEVVKQVTTYFGDKVFNTIIPRNVKLSEAPSHGLPISSYDAQCAGARSYEKLAREIVARDGQR
What are the official names of this protein?
Protein Soj homolog.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: IOLG_CORGL
Sequence: MSKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAEDAPGAQAFTRIEDAIAADAVDAVLIAVPGQFHEPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKPHIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPSVGESYTQSMLITDSVVHEFDVIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVATEAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAGPNAWDGYLVALSCEAGVKALDGGVIPVDAAPRPDFYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: PSBM_SYNP2
Sequence: MQVNDLGFIATILFVLVPTVFLLILYIQTNKTAS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: Y2688_MYCBO
Sequence: MTDADELAAVAARTFPLACPPAVAPEHIASFVDANLSSARFAEYLTDPRRAILTARHDGRIVGYAMLIRGDDRDVELSKLYLLPGYHGTGAAAALMHKVLATAADWGALRVWLGVNQKNQRAQRFYAKTGFKINGTRTFRLGAHHENDYVMVRELV
What are the official names of this protein?
Uncharacterized N-acetyltransferase Mb2688.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: HEMTM_THEHE
Sequence: GWEIPEPYVWDESFRVFYEQLDEEHKKIFKGIFDCIRDNSAPNLATLVKVTTNHFTHEEAMMDAAKYSEVVPHKKMHKDFLEKIGGLSAPVDAKNVDYCKEWLVNHIKGTDFKYKGKL
What is the function of this protein?
Myohemerythrin is an oxygen-binding protein found in the retractor muscles of certain worms.  The oxygen-binding site contains two iron atoms.
What are the official names of this protein?
Myohemerythrin, MHr.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: GCKR_HUMAN
Sequence: MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEIFQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVSFNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDVRGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEAVRSALAGPGQKRTADPLEILEPDVQ
What is the function of this protein?
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme (PubMed:23621087, PubMed:23733961).  Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10456334).  The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (PubMed:23621087, PubMed:23733961).
What are the official names of this protein?
Glucokinase regulatory protein, GKRP, Glucokinase regulator.
What is the protein family that this protein belongs to?
Belongs to the GCKR family.
Protein: RNH_SHIBS
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CHRVO
Sequence: MAHKKAGGSSRNGRDSEAKRLGVKVYGSELIPAGSIIVRQRGTKFHAGENVGQGKDHTLFAKVDGYVEFTVKGAQQRKTVNVVPYTGVDGE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: MENG_BACFN
Sequence: MNYPQEKIKPYSNDGKKSEQVEQMFDNIAPAYDQLNHTLSLGIDRSWRRKAINWLKPFRPQQIMDVATGTGDFAILACHELQPEQLIGTDISEGMMNVGREKVKKEGLSEKISFAREDCTSLSFADNRFDAITVAFGIRNFEDLDKGLSEMYRVLKTGGHLVILELTTPDRFPMKQMFTIYSKIVIPTLGKLLSKDNSAYSYLPQTIKAFPQGEVMKNVISRVGFSQVQFRRLTFGICTLYTATK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.