PharMolix/UniProtQA huggingface dataset:
Protein: GLMM_ACIB3
Sequence: MSYFGTDGIRGKFGQMPITPEFALKLGFAAGKVLKRTSPKNKPLVVLGKDTRLSGYILESALQAGLNAAGVYVHLLGPLPTPAIAHLTRALHAHAGIVISASHNPYFDNGIKFFSSEGKKLPDSLQEEINKELEKDLFIEDTANLGKSVRVTDANGRYIEFCKSTFPYHFDLNNLKIVVDCAHGAAYSVGPSVFRELGAKVVALYNEPDGLNINENCGSTHPESLQKAVVEHGADLGIAFDGDADRVVMVDKFGNLIDGDHILYILATQAKNKPAGVVGTVMSNMALEVALEKANVGFVRAKVGDRYVLQALEENGWVTGGEPSGHILTLDKSTTGDAIIAALQVLTVMVEQNKALHELVNGFKLYPQVLVNVRLEQMLDPYSIPALVAEFNKAEEQLKGRGRILIRKSGTEPVIRVMVEGDNEQEVKTLAEHLANAVRSQAQVA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: YAP1B_XENLA
Sequence: MEPGSQQQPSAPGQQPPPVGHQIVHVRTDSETDLETLFNAVMNPKNANVPQTLPMRMRKLPDSFFKQPEPKSHSRHVDQTTTWQDPRKAMLSQINITAPTSPPVQQNIMTPTAMNQQRLSQSAPVKSPPALQPQSPPSGVLGSGGNQQMRLQQLQMEKERLRLKHQELLRQVRPQELALRSQIPPMEQDSGPPNPVCSSGISQELRTMTMNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGEAITQSTIPTQQNRFPDYLETLPGTNVDLGTLEGEAMNVEGEELMPSLQEALSSDILNDMETVLAATKLDKESFLTWL
What is the function of this protein?
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity).  Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (By similarity).
What are the official names of this protein?
Transcriptional coactivator YAP1-B, Yes-associated protein 1-B, Protein yorkie homolog-B, Yes-associated protein YAP65 homolog B.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.
Protein: NUOI_MYCGI
Sequence: MPKFLDAVAGFGVTFGSMFKKPVTEEYPEKPGPVAKRYHGRHQLNRYADGLEKCIGCELCAWACPADAIFVEGADNTEAERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTNDYEMADDNRADLIYGKDKLLAPLEPGMGAPPHAMAPGATDEDYYRGTVSPSAEADAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BIOH_SALHS
Sequence: MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBB4_PHAVU
Sequence: KSGHRHESXBSTBXASXSSKPCCBHCACTKSIPPQCRCSBLRLNSCHSECKGCICTFSIPAQCICTDTNNFCYEPCKSSHGPBNN
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor PVI-4.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: CBPYA_NEOFI
Sequence: MRVLPATLLVGAATAAAPPFQQILGLPKKGADTLAKPLHDLQEQLKTLSGEARHLWDEVANHFPNNMDHNPVFSLPKKHTRRPDSHWDHIVRGADVQSVWVTGASGEKEREIDGKLEAYDLRVKKTDPSALGIDPGVKQYTGYLDDNENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPSSINEKIKPIYNDFAWNSNASVIFLDQPVNVGYSYSGAAVSDTVAAGKDVYALLTLFFKQFPEYAKQDFHIAGESYAGHYIPVFASEILSHKKRNINLKSVLIGNGLTDGLTQYDYYRPMACGEGGYPAVLDEASCQSMDNALPRCKSMIESCYNTESSWICVPASIYCNNALLGPYQRTGQNVYDIRGKCEDTSNLCYKGMGYVSEYLNKREVREAVGAEVDGYESCNFDINRNFLFHGDWMKPYHRLVPGLLEQIPVLIYAGDADFICNWLGNKAWTEALEWPGQKEYAPLPLKDLVIEENEHKGKKIGQIKSHGNFTFMRLYGAGHMVPMDQPEASLEFFNRWLGGEWF
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: DIVIB_BACCR
Sequence: MNNSKVIKLQDRVPKLKNQKKKNKKNVNHRLILYISILFLLVLFLIYFRSPLSNIKKISVFGNHYMTDEQVMKDSGVTYDTSYFRVTAHKAEENLTKRKEIKAVNVKKRFPNNIDIHIEEYLTIGYINKEGKLQPLLENGKTLDVLPNGKLPVAAPIFEPFKEEKMKELIAELEKLTPAILKSISEIRYSPTNANEDHLTLYMNEGYEVSTTIQNFAKRMEAYPLILKTIEPGKKVLIDLEVGAYTKELGAEEKKE
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: COG7_RAT
Sequence: MDFSKFLADDFDVKDWINAAFRAGPKDGAAGKADGHAATLVMKLQLFIQEVNHAVEETSLQALQNMPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDIAVISAKLTGMQSSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLATWQELCQRDLPLDRQLTGLYHALLGAWHTQTQWATQVFKNPYEVVTVLLIQTLGALVPSLPMCLSEAVERAGPELELTRLLEFYDTTAHFAKGLEMALLPHLQDHNLVKVVELVDAVYGPYKPYQLKYGDLEESNLLIQISAVPLEHGEVIDCVQELSQSVHKLFGLASAAVDRCAKFTNGLGTCGLLTALKSLFTKYVSHFTNALQSIRKKCKLDDIPPNSLFQEDWTAFQNSVRIIATCGELLRQCGDFEQQLANRILSTAGKYLSDSYSPRSLAGFQDSILTDKKSPAKNPWQEYNYLQKDNPAEYANLMEILYTLKEKGSSNHNLLSVSRTALTRLNQQAHQLAFDSVFLRIKQQLLLVSRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQGEELPELDNMADNWLGSIARATMQTYCDGILQIPAVTPHSTKQLATDIDYLINVMDALGLQPSRTLQNIATLLKAKPEEYRQVSKGLPRRLAATVATMRGVNY
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 7, COG complex subunit 7, Component of oligomeric Golgi complex 7.
What is the protein family that this protein belongs to?
Belongs to the COG7 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: Y1237_ARCFU
Sequence: MRAINKFLITVCIALLASVAVALGDGEETGEAEEFKVIDHSKVWEEKGITKYEGSKTCIQCHEDKVRQFFHSYHYQLFSENEGINGKTMIFGGKMAFNDYCMAMFVNNGTKVVNWIGYITLKKAPEGYEDLVGSFTGLTGCSMCHGVGMGLPPSPQESEEQLGNIDCLACHAKPDVYVSGVLGIKLGLKNVTKDDQGRWRYVINVPTEELAKSIINRPQSKNCLACHAFSGGGPHLKRPNIAPDLLNPELAAEFDVHFKAGLGCTDCHSGENHEFGTNSVDTWSREGEGAEVQQLPH
What are the official names of this protein?
Uncharacterized protein AF_1237.
Protein: RL16_RICPU
Sequence: MLAPKKQKFRKAHKGRVASTAKAGTTLAFGSFGLKSIDGWRVTARQIEAGRKAATRCMKRQGRLWIRIFPDVPVSKKPAEVRMGKGKGSPEFFAVRVSPGRIMFEIEGVEENVALRALELASAKLPVRTRIVRRYE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NOP58_BOTFB
Sequence: MAPLFILTETAAGLVLFKADKKLLKKDDVASEIETAEGINGLLKLKQFQKFDSAATALEEVASLVEGKVSPMLASLLDTLKDEKKASLAVADPKLGQAINKLPGLTLTPISDSKTNDIFRGIRDHLPSLIPGLLPEHISTMSLGLSHSLSRHKLKFSPDKVDTMIVQAISLLDDLDKELNTYAMRVKEWYGWHFPEMGKIVNDNLAYARVILKVGMRVNTSSTDLADILPEEIETAIKAAAEVSMGTEITQEDLDNIKLLAEQVVGFTEYRQQLSSYLSARMQAIAPNLTELVGDLVGARLIAHAGSLMNLAKSPASTIQILGAEKALFRALKTKHDTPKYGLIYHASLVGQATGKNKGKIARMLAAKAAIGLRVDALSDWSAQGEGKGDDVDDEERSALGVTSRAKIERHLRGLEGKPLLPRGVAVGPNGKATSAPGKWEVKEARKYNADADGLAGDEPAAAVPIREKKNKKLIEEVAEESGSDSSDDSDASEKKPKKGDKEAKKAEKAAKKAEKAAKKAAKEAKKAAKAEKEAKKSDAPEVNGSKKRKSEDDGEKSEKKKKKKSKD
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TOLB_CHLTE
Sequence: MRSTRNSFACLCIMLFGMLFVPFTLRAEEVGEYIAIRKEGASRIAVVLDKTSADGGKQREWARSLDVTINKGLDFTGLFNLLPAPLNIRNGQNGGLNFASIASVGGDIYAGGSVTKRSGRPVLEMHVYDSSGKSLLARTYTGEESQLRAIGLRFCADLVELLTGKRSVFGTRIVFVANRTGNKEIYMCDFDGENVVQLTNSRSISLTPAVSPDGTYIAWTDYTSGKPNLYIKNIATGAKVSVNKHGVCISPAWRPGTNTLVTTLSYEGDQDLYLIRADGTVERRLTKGGGIDVSPTFSPDGSKMAFVSTRQGGPQIFIQDMNSGQVRRLTYSGIYNTQPSWSPNGDKILYSSMQKSGEINIFSINVDGSGLLQLTSGSGNNEHPSWSPDGSMIVFSSTRDGRRRLYVMNADGSNQRPLLNMQGEQQQPSWSVSK
What are the official names of this protein?
Protein TolB homolog.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AGUA_SHEB5
Sequence: MTNANVDATPLTTKPSQDGFYMPAEWAAQQAVWMIWPYRPDNWRSAGAYAQATFAKVADAIGGATPVYMGVPKAFLAEAQKVMPSHVTLVEMDSNDCWARDTGPTVVVNDNGECRGVDWGFNAWGGHNGGLYFPWDKDEQVAQQMLKQHGFARYSAPLILEGGSIHVDGEGTCMTSAECLLNANRNPELTKEQIEDLLRDYLNVKQFIWLQDGVYMDETDGHIDNMCCFARPGEVILHWTDDETDPQYPRSKAALDVLQNTVDAQGRKLKIHLLPQPGPLYCTEEESLGVTEGTGVPRTAGERLAGSYVNFLITNNRIVFPMLDPATDDIAAQKLQEIFPEYEIIGVPAREILLGGGNIHCITQQIPSGK
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: CLPS_ECOLI
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: Y846_SYNY3
Sequence: MKLTTKSHYSVKALLDLALQPDYGPASVKAIAERQNIPGPYLEKLLITLRRAGIVNAYRGVRGGYQLAQAPDQISLGQILAALEESLEPFPQYGDDQSLAEDWVTLSVWRQLHQKFVKALYSITLADLYYDARSWQAAQGEGINFIV
What are the official names of this protein?
Putative HTH-type transcriptional regulator slr0846.
Protein: E70B1_ARATH
Sequence: MAENGEEKLLAVARHIAKTLGHNESMADDILQIFSNFDGRFSREKLAEGQAGEDGSGVATLERALNSIDGQISRFVAADQPIWADPADSAAFLDTIDELVAIIREWSPMASEKPIGICLTRADDMMQQAMFRIEEEFRSLMERGAESFGLNPQGDAGAMNHRFDSEEEEDDDRDFNNGDDIQIPVAQPLTDYDLIIDALPSATINDLHEMAKRMLGAGFGKACSHVYSSCRREFLEESMSRLGLQKLSIEEVHKMPWQELEDEIDRWIKAANVALRILFPSERRLCDRVFFGFSSAADLSFMEVCRGSTIQLLNFADAIAIGSRSPERLFKVLDVFETMRDLMPEFESVFSDQFCSVLRNEAVTIWKRLGEAIRGIFMELENLIRRDPAKAAVPGGGLHPITRYVMNYLRAACRSRQTLEQVFEESNGVPSKDSTLLTVQMSWIMELLESNLEVKSKVYKDPALCYVFLMNNGRYIVQKVKDGDLGLLLGDDWIRKHNVKVKQYHMNYQRSSWNKMLGLLKVDNTAAGMNGLGKTMKEKLKQFNIQFDEICKVHSTWVVFDEQLKEELKISLARLLVPAYGSFIGRFQNLGDIGKNADKYIKYGVEDIEARINELFKGTTTGRK
What is the function of this protein?
Component of an exocyst subcomplex specifically involved in autophagy-related, Golgi-independent membrane traffic to the vacuole.  Regulates autophagosome formation and autophagy-related Golgi-independent import into the vacuole.  Positive regulator of both abscisic acid (ABA)-promoted and mannitol (drought)-promoted stomatal closure (PubMed:27956469).
What are the official names of this protein?
Exocyst complex component EXO70B1, AtExo70b1, Exocyst subunit Exo70 family protein B1.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome. Endomembrane system. Note=Displays a punctate pattern. Colocalizes with PUB18.
Protein: HDDA_MYCTU
Sequence: MAILRGRAPLRLGLGGGGTDVEPYSSQFGGRILSVTIDKYAYAFAERGTGDEIAFRSPDRDRAGQASIDDLASLEEDFPLHVAVYRRVIAEFNGGTPFPLQLATQVDAPPGSGLGSSSALVVAMLLTTCALIGSSPGPYELARLAWEIERVDLGMAGGWQDHYAAAFGGFNFMESRPNGEVVVNPLRIRREVIAELEASLLLYFGGVSRLSSEVIADQQRNVVERDADALAATHSICAEALEMKDLLVVGDIPGFADSLLRGWQAKKRTSTRISNPAIEHAYQVAQSSGMVAGKVSGAGGGGFLMMIVDPRRRIEVARSLERECGGSVAPCLFTKGGAVTWHIPESTAPVRRGVADAVASALGNAGILLCAGCVLATSHSTWRVPV
What is the function of this protein?
Catalyzes the phosphorylation of D-glycero-alpha-D-manno-heptose 7-phosphate at the C-1 position to form D-glycero-alpha-D-manno-heptose 1,7-bisphosphate (By similarity).  Exhibits ATPase activity in vitro (PubMed:33412198).
What are the official names of this protein?
D-glycero-alpha-D-manno-heptose 7-phosphate kinase, D-alpha-D-heptose 7-phosphate kinase, MtbHddA.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family.
Protein: DNAA_CLOBJ
Sequence: MSTHLTETWEKAINIIKGELTEVSFNTWIKSINPISLENNSLKLAVPNDFTKGILESRYKDLIVNALKLLTSKKYNIDFIVTTEEKIEKNHNNEKSNIVVNDEMSTMLNPKYTFDSFVIGNSNRFAHAASLAVAESPAKAYNPLFIYGGVGLGKTHLMHAIGHYILHNNPKSQVVYVSSEKFTNELINSIKDDKNVEFRNKYRNIDILLVDDIQFIAGKERTQEEFFHTFNALYEANKQIIISSDRPPKEIPTLEDRLRSRFEWGLIADIQAPDFETRMAILKKKADVEKLNIPNEVMVYIATKIKSNIRELEGALIRIVAFSSLTNKEISVDLASEALKDIISSKQTRQVTIDIIQEVVANYYNLKIEDLKSARRTRNIAFPRQIAMYLSRKLTDMSLPKIGEEFGGRDHTTVIHAYEKISNNLKKDESLQNAIKELNKRINQK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SHEWM
Sequence: MAIIKCKPTSAGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRIIDFKRIKDGIPAKVERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKIQSGIDAEIKVGNALPLRNIPVGSVVHAVEMKPGKGAQIARSAGTYVQVVARDGEYATLRLRSGEMRKVPVDCRATMGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPIDHPHGGGEGRTSGGRHPVSPWGVPTKGYKTRSNKRTDKYIVRRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL31_CHLPB
Sequence: MKKDIHPKYTTVTVTCANCGNSFETRSTKESIKVDICSNCHPFYTGKQVLVDTAGRVERFKKRFAKKNASSSASE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PIP_FLAJ1
Sequence: MIPIKTPVGEFKVWIKRFGTNPKIKVLLLHGGPAMTHEYMECFETFFQREGFEFYEYDQLGSYYSDQPKDSSLWTIDRFVDEVEQVRKAINADKDNFYVLGNSWGGILAMEYALKYQQNMKGLLVSNMMASAPEYGKYADEVLAKQMKPEILKEIRDLEAKKDFENPRYMELLLPNFYKEHLCRLNEWPDGLNRASKHVNGEIYTLMQGPSEFGISGRLAKWDIKNRLHEITIPTLMIGAKYDTMDPKAMEEQSKLVKKGRYLYCPNGSHLAMWDDQKVFMNGVIQFINDVNDEKVN
What is the function of this protein?
Releases the N-terminal proline from various substrates.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
Protein: ARLY_MACFA
Sequence: MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQCTFKLSPNDEDIHTANERRLKELIGETAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLSVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHRENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNELSLQELQTISPLFSGDVSCVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQTQQA
What is the function of this protein?
Catalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues (By similarity).  Essential regulator of intracellular and extracellular L-arginine pools.  As part of citrulline-nitric oxide cycle, forms tissue-specific multiprotein complexes with argininosuccinate synthase ASS1, transport protein SLC7A1 and nitric oxide synthase NOS1, NOS2 or NOS3, allowing for cell-autonomous L-arginine synthesis while channeling extracellular L-arginine to nitric oxide synthesis pathway (By similarity).
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: FSDR_FUSHE
Sequence: MSTGPPSGISLVSMTTPRKSGQHTPESWSKWTHPSIEPLFTKRVMKPLPSWTGAFSLVSEFFTHEHQVFPCFNAPAFMCLLGQQYSVECTESPAWWVSLNSVLAIAQRRRAEAAQSAEAEDLAWAYASNALAGTWDILMRSTQLSSVQALLAIAWFFIGTPNPQPSFMLVGCAVRLAHSIGIHVESQDPSISPAEANLRKKVFWIAICLDQELCLRTGRSPCHDLNAGYVDPPMDSLDETEITKTVDGHELNLFQSQIQLAVIQGAIYRDLHSGKAPPNCIADSVADLLQKLENWRIEFAPTLTHDSTVRCEHHGLMRLYLSYYNAVIVVSRAHSLAYWVSPNHPAFSALPSSMRDSIENCLNASRCIIELSKLIPVTWRSFHWDIISILMSAVVILCIMAIRNPMNELATNDMGSVGDVLHIFKTLDEAYGNTYLTQVQKVCEKLYRKAHYAMQSSNAQPVESVDVVSPALEDSSNANQQQARHTDSTLEFNPNAFEQTMPYPLPMGWDLDTFLWTPTI
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of fusaridione A (PubMed:23614392).
What are the official names of this protein?
Fusaridione A cluster transcription factor fsdR, Fusaridione A biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMT_BACCZ
Sequence: MIKVVFMGTPDFSVPVLRRLIEDGYDVIGVVTQPDRPVGRKKVLTPTPVKVEAEKHGIPVLQPLRIREKDEYEKVLALEPDLIVTAAFGQIVPNEILEAPKYGCINVHASLLPELRGGAPIHYAIMEGKEKTGITIMYMVEKLDAGDILTQVEVEIEERETTGSLFDKLSEAGAHLLSKTVPLLIQGKLEPIKQNEEEVTFAYNIKREQEKIDWTKTGEEVYNHIRGLNPWPVAYTTLAGQVVKVWWGEKVPVTKSAEAGTIVAIEEDGFVVATGNETGVKITELQPSGKKRMSCSQFLRGTKPEIGTKLGENA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ARLY_CANAX
Sequence: MSQQQDKQPSENKLWGGRFTGATDPLMDLYNASLPYDKVMYDADLTGTKVYTQGLNKLGLITTEELNLIHQGLEQIRQEWHDNKFIIKAGDEDIHTANERRLGEIIGKNISGKVHTGRSRNDQVATDMRIFVRESLLNLSKILHQFITAILERAHKEIDVLMPGYTHLQKAQPIRWAHWLSSYATYFTEDYKRLQEIITRVNQSPLGSGALAGHPYGIDREFLAKGLGFDGVIGNSLTAVSDRDFVVESLFWSTLFMNHISRFSEDLIIYSSGEFGFIKLADAYSTGSSLMPQKKNPDSLELLRGKSGRVFGQLSGFLMSIKSIPSTYNKDMQEDKEPLFDALTTVEHSILIATGVISTLSIDKQNMEKALTMDMLATDLADYLVRKGVPFRETHHISGECVRKAEEEKLSGIDQLSFEQFQQIDSRFEKDVMETFDFEASVERRDALGGTAKSAVLKQLENLKSILS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: PAN1_ASPTN
Sequence: MYSSSNSFLGGANSARPGQQPPFMQQQQQPSYSQFPPGQQQQPQPTGFAPQPTGYAQPQLSSFGSQLQPQPTGFPSGQLQPQFTGFPGAAPQQSQQPQPTGFQPQQPQFTGYPPQSQPPQLQVPAATGLPLRPAQTSSEIANSFRDASGAAPPPPPKSSGSKIPNIRLSFITAQDQAKFEQLFKSAVGDSQTMSGDKARELLLRSRLSGSDLSKIWVLSDSTKSGQLFFPEFALAMYLCNLRLTGRDLPDALPETIKNEVSSMVDIISFQVPDTQPEPVVRTNVPNFDAPLMENKLAPPAPQQPQPQQPTNSQLLNQLTAQPTGFLSQPTGLSPNQAPFGQQSNLAPQPTGLPGQPQQQSLQPQPTGFMSNPQPTGYSGPRPPVPPIPTGYASNLSPSQTGGMSGLVAQPTGIPGQWGFVNAPSSGLPNIEALKQQLMPQPGREGGFSTAGLAGNASIPWAITKEEKKIYDDLFRAWDGFRKGFIGGDTAIEIMGQSGLNRQDLERIWTLADPNNRGRLNMDEFAVAMHLIYRKLNGYPVPNRLPPELIPPSTRNLNDSIGTIKSLLSQDAESRKATGAFLQPQKTGVSYLKEHSFRGGAVSPGVGRKDATLFKNDDQAAAGYRSSARRRVGNNGRTPSPAASSQASEDELSVEQLKKKIRETQIMLDAVDFQDETRAEEDDALDRRDRREAESLMDRIRRVQDEIDTHPNAAFRNLDNGAERRSLRRQLQAYEDQVPQVASEVRRVEREIAEARLELFRLKDAKAHPNSALNIVGTGPGGTVTEADRIKARARARMQARAAELAGRPAPATQDDEGAAARRLESESANVKADREKNDAMTRDVEDSVKDFARSLEDSLKDVSENSTREHEKRRWEDALGVEDVIRDFIYDLKRNSRTAHIRKEEASRASPSQSQQSRYDEPPAVRPSPPPSTGSTGSLPGTTHEDRVAAAKERAQKRIAERLAAAGLKPHSEASETLVQRQEREKREREERLKRAEEEDALREQERQRRLAEERGTPAQPSTKPIGKKPPPAPPSRRARTDSADQSEAKKAADEAAKVEQTAREQAIREEQQVQEEETKRLEDEARQREEEFMKEKEAQEARLRALQEQVQQGKIKKQEEKRRKEEAERRAKEQEAKLAAQRAELEAAKERERQLQRELEAMEEESSSDDEGPEFATPRNGSPAQTEAPTAEAPPPPPPAPATAPPVPAIAEPEAPTSPATSPASSRANLSPEAESKNPWFKKIGQPADSQPAPVPQAATTPSDTHSTNPFHRLAQQQESTAPAFTGSAPLERKTRARPEDDDDWSAAGSEFDSSDDEDDRAGGGSAKQLASILFGTMAPPRPLSAMDDKSPSKTPTPVQETPAPAPEADAAPSAPVAAPPPPPPPPVPAAAPNGSAGAPPPPPPPPAPPMAPPPPPAGVPPPPAPPAAPAGAADRGALLASIQAGKGLRKVQTNDRSTSSTAGRVLD
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein pan1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: C1QBP_HUMAN
Sequence: MLPLLRCVPRVLGSSVAGLRAAAPASPFRQLLQPAPRLCTRPFGLLSVRAGSERRPGLLRPRGPCACGCGCGSLHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRKVAGEKITVTFNINNSIPPTFDGEEEPSQGQKVEEQEPELTSTPNFVVEVIKNDDGKKALVLDCHYPEDEVGQEDEAESDIFSIREVSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVELSTALEHQEYITFLEDLKSFVKSQ
What is the function of this protein?
(Microbial infection) Involved in replication of Rubella virus.
What are the official names of this protein?
Complement component 1 Q subcomponent-binding protein, mitochondrial, ASF/SF2-associated protein p32, Glycoprotein gC1qBP, C1qBP, Hyaluronan-binding protein 1, Mitochondrial matrix protein p32, gC1q-R protein, p33, SF2AP32.
What is the protein family that this protein belongs to?
Belongs to the MAM33 family.