PharMolix/UniProtQA huggingface dataset:
Protein: GLAH_ECO27
Sequence: MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLPELTFTEQTTNRFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDLFFRHPLARRPMRFAAPPSKNVSKDVFYPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: UD17_HUMAN
Sequence: MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
What is the function of this protein?
Lacks UGT glucuronidation activity but acts as a negative regulator of isoform 1.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A7, UGT1A7, UDP-glucuronosyltransferase 1-7, UDPGT 1-7, UGT1*7, UGT1-07, UGT1.7, UDP-glucuronosyltransferase 1-G, UGT-1G, UGT1G.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL392_ORYSJ
Sequence: MPSHKTFRIKKKLAKKMRQNRPIPYWIRMRTDNTIRYNAKRRHWRRTKLGF
What are the official names of this protein?
60S ribosomal protein L39-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: PYRD_PLAF7
Sequence: MISKLKPQFMFLPKKHILSYCRKDVLNLFEQKFYYTSKRKESNNMKNESLLRLINYNRYYNKIDSNNYYNGGKILSNDRQYIYSPLCEYKKKINDISSYVSVPFKINIRNLGTSNFVNNKKDVLDNDYIYENIKKEKSKHKKIIFLLFVSLFGLYGFFESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEKKNNFNKNNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSKS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: Y1042_SACS2
Sequence: MVKVMVVAEVRPSEDVNKVLSAISNFFDFEKMNTRKEGIIDILVLEARTLKSLLKFHRVLRNERILDSARKYLMKGIEGNTIAFMIHKQAAAVGVLSFVDSDKESPLGAIKFYIEYQNPKEIVDWLAPKTAHGVPLWDNPVPPDV
What are the official names of this protein?
UPF0201 protein SSO1042.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: RL4_CAUVC
Sequence: MKLDVIKLDGGKAGSVDLDDAIFGIDEIRGDILQRVVTWQLAKRRSGNHKIQVRNEVSRTSKKMYKQKGTGGARHGSRRAAQFVGGAKAHGPVVRSHAFDLPKKIRALALRHALSSKAKAGSLVVVDSVALTEAKTAALRATFDKIGLKNALVIAGPEVDANFKLAARNIPNVDVLPNAGLNVYDVLRRQTLVLTKDAVEAISARFAEKEAA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: AGO3_DROME
Sequence: MSGRGNLLSLFNKNAGNMGKSISSKDHEIDSGLDFNNSESSGERLLSSHNIETDLITTLQHVNISVGRGRARLIDTLKTDDHTSNQFITSESKENITKKTKGPESEAIASENGLFFPDLIYGSKGSSVNIYCNYLKLTTDESKGVFNYEVRFFPPIDSVHLRIKYLNDHKDKLGGTKTFDGNTLYLPILLPNKMTVFISKAEDVELQIRILYKKKEEMRNCTQLYNILFDRVMKVLNYVKFDRKQFDPSRPKIIPLAKLEVWPGYVTAVDEYKGGLMLCCDVSHRILCQKTVLEMLVDLYQQNVEHYQESARKMLVGNIVLTRYNNRTYKINDICFDQNPTCQFEIKTGCTSYVEYYKQYHNINIKDVNQPLIYSIKKSRGIPAERENLQFCLIPELCYLTGLRDEVRSDNKLMREIATFTRVSPNQRQMALNKFYENVSNTPAAQEILNSWGLSLTNNSNKISGRQMDIEQIYFSKISVSAGRSAEFSKHAVTNEMLKVVHLSKWIIIHLRNYRQAATSLLDNMKQACESLGMNISNPTMISLDHDRIDAYIQALRRNITMNTQMVVCICHNRRDDRYAAIKKICCSEIPIPSQVINAKTLQNDLKIRSVVQKIVLQMNCKLGGSLWTVKIPFKNVMICGIDSYHDPSNRGNSVAAFVASINSSYSQWYSKAVVQTKREEIVNGLSASFEIALKMYRKRNGKLPTNIIIYRDGIGDGQLYTCLNYEIPQFEMVCGNRIKISYIVVQKRINTRIFSGSGIHLENPLPGTVVDQHITKSNMYDFFLVSQLVRQGTVTPTHYVVLRDDCNYGPDIIQKLSYKLCFLYYNWAGTVRIPACCMYAHKLAYLIGQSIQRDVAEALSEKLFYL
What is the function of this protein?
Acts via the piwi-interacting RNA (piRNA) metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.  Associates predominantly with sense piRNAs that contain adenine at nucleotide 10, but shows no preference for uridine at the 5' end.  In testis, however, associates with Su(Ste) and AT-chX-1 piRNAs mostly produced from antisense precursors.  Shows RNA cleavage activity.  In the germline, acts to amplify pools of antisense piRNAs, among others Su(Ste), AT-chX-1 and roo, and to limit sense piRNA accumulation.  Forms a complex with smg, twin, aub and specific piRNAs that targets nos mRNA (and probably other maternal mRNAS) for deadenylation promoting its decay during early embryogenesis.  Involved in transposon silencing in the adult brain.
What are the official names of this protein?
Protein argonaute-3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis. Also found in prominent but discrete foci in the germarium. Unlike other nuage components, does not accumulate at the posterior pole in oocytes and early embryos. In the cytoplasm of syncytial embryos, accumulates in discrete foci.
Protein: UVRB_RICB8
Sequence: MSNFSIISDYKPAGDQPKAIDEIIKGLNNKKRSQMLLGITGSGKTFTMANIIERTNRPTLIMAHNKTLAAQIYSEMKSIFPKNAVEYFVSYYDYYQPEAYIPKTDVFIEKDSSINEQIDLMRHSATRSLLERRDVIVVSSVSCIYGLGSPDLYYQMTVNLEPGKSYPRDKLLNDLVNLQYERNDIGFERGCFRVKGDNVDVFPSHYSDKAWRLSFFGNELEYIHEFDPLTGEKLVKLDKAIIYGNSHFVMPKETVNKAISEIEEELQKRIAFLKSQDKLLETQRINQRTQYDLEMLTETGSCKGVENYSRFFTGRKAGEPPPTLFEYLPKDALLFVDESHVSVPQIRAMYNGDRARKEVLVEHGFRLPSALDNRPLKFEEWDNFRPQTVFVSATPSLFELNETGGEVVELIIRPTGLLDPECIIKPATNQVEDLVGEIQSTIAKGFCVLVTTLTKKMAEDLTNYLQELKYKTSYLHSNVHTLERIEILRDLRQGTIDILVGINLLREGLDIPECGLVAILDADKEGFLRSEVSLIQTIGRAARNSEGRVILYADKMTKSIDKAISETMRRRTIQQEHNEKYGIIPKTINRTIHALAELEKVDSKLDKKQTHNLFENPAKLKAHIDKLRKEMLKAASNLEFEQAAKLRDQLKTLEEAALELS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_GLOVI
Sequence: MLITSIEAHEILDSRGNPTVEAQVALENGTTGSAIVPSGASTGEKEAVELRDSDPKRYGGKGVLSAVANVNDSIAPEIIGMEVTDQRSIDRKMIEIDGTANKATLGANAILAVSMAVARTAALSLGLPLYRYLGGTNASLLPVPCMNVINGGKHADNTVDFQEFMIAPHNAPNFAEALRMGAETFHALKSILRGKGYSTGVGDEGGFAPDLKSNEEAVEVILLAIEKAGYRPGEDISICLDPATSEMWKDGKYLFFKSDQSTKTSEEMVDLWASWAGQYPIVSLEDGMGENDWEGWKMLTDRIGATVELVGDDLFCTNAKILAEGIEKGVANSILIKLNQIGSVSETLDTIELAVKHNYKCFVSHRSGETEDTTIADLTVATAAGQIKTGSGCRSERVAKFNQLLRIERQLGEAARFAGKSAFAR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSBE_RIPO1
Sequence: MSGSTGERPFSDIVTSIRYWVIHSITIPMLFIAGWLFVSTGLAYDVFGTPRPDQYFTQERQELPIISDRYKASQQIQEFNK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: LPTE_ECO27
Sequence: MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYGA_STRP6
Sequence: MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEMSDQDMLLENFEKFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKKLGFPLLDEATRAILLAEDDE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3HAO_SHEWM
Sequence: MSKLAAFNFQQWIDEHQHLLKPPVGNVQIWENTDMMVTVVGGPNQRTDFHDDPVEEFFYQLKGDMVLKIIEEGKCHDLFIREGDIFFLPPHVRHSPQRPMPGSIGLVIEPKRPEGAKDAFEWYCFKCDGLVHRVEVLLKSIVRDLPPIYQAFYQDEQARTCPQCGELHPGKEPPQGWVTLLENKEQDKS
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
Protein: PUR2_METAC
Sequence: MKMKILLIGGGGREHAIAEGIKESKHNPILYALMAKKNPGIAALCEDFLLEKETEVEKIVEYAKARNIEMAFVGPEAPLAAGVADALWEAGIPVVGPKKACAVIEFDKAWARNFMKKYGIEGCPAYEVFTEEAPAHAFIEKLGDVAVKPSGLTGGKGVKVMGDQLPDLKAAKDYTSELLEKGPVVIEERFIGEEFTLQAFVDGKNLAFFPAVQDHKRAYEGDLGPNTGGMGSYTDAGEILPFMLAGDIEQAKKIMQHTVTALHEETGTGYQGVLYGQFILTASGPKVVEFNARFGDPEAMNVIPLIETDFTEIMSAVVKSTLDSLPVKFSRKATVCKYAVPAGYPDNPEKDSEVLVGDVGEASVYYASVYEKEGKIYTTGSRAVAVVGRAETIDAAEKIAQNALENIQGKLFFRKDIGTASLIQKRIDHMKELRGGLSQKQ
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: LCSL_PURLI
Sequence: MHLDWTLVLASRIRKVKCDEKKPCCQKCIDTGRTCDGYESPFRVVTSRSIINGARASGIPGAASRPVRPALTEISPADIDLLNRYFSTKTMFDVKLGCDEEAREVLEASLTDPTVRHAVSSLRSLREHLETSGDVSASAAQQSPSYGYDYGVQQYCMALGGLASNLSSPGSNALKSALLCCQIFISIEQVRGNYGTMAQHIIQGLGIMHEYRARPTLDDANNLVPAHHAQLPLLDAFVIKLFAAPCKFAEPSATADKEGGKAVSMCAISRHEQTVGSRNLRTIVPDMRTELTRISTSTLDFLVKVSSVDSAGNALRLLPEKTALLESLKSWLMDLELVHADIKSPGTEPLAVSFLRLFHQILKIILVEALNSSSNLQAELRTENDRLQGIGSIIDERVQSQRKNSSALDLIDNRLKCPA
What is the function of this protein?
Transcription factor that may coregulate the expression of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic.
What are the official names of this protein?
Transcription regulator lscL, Leucinostatins biosynthesis cluster protein L.
What are the subcellular locations of this protein?
Nucleus.
Protein: IREA_ASPFU
Sequence: MRWRLPGARTTLPASVALLLLPILVAPQQLQEHDDLPSTLSVPLSPTQRSFDHHPLPTINVKSNDASALATMALAGPGRAVRARPAQASSSSAGLAPQLHARSLQDWEVEDFVLLATVDGSIHARDRRTGAARWALEVPSSPMVESIYHRANRSSFDRAQPEDDFLWIVEPSQDGNLYIYSPGPDAGLQKLGLTVKELVEQTPYSGTDPAVTYTARKETTLYTVDARTGNILQVFSSRGPITSGHGCRKVDGFDLEAEECDTPSGTLVLGRVEYAVAIQNTETGDPICTLKYSEWTANNRDMDLQSQYFRTMDQSHIYSMHDGVVLGFDHSRMDRPRYTQRFSSPVVRVFDVARPINVESPEAATPLVLLSQPLQPPDPDYGSLDDRDARVFVDCTSAGGWFAMSEETYPLVTGRAKMAQCYEKDYLRHGQPLTSLPTSQQRDALAGVHSLNGPRVVRNTPSISGPSPLELANDTPRELMRSPSELALPPALRHSTIIRKGWDNAVDIFVTILLLFFGAFIYFNSHNIQELAKQKLDVKNIIASYAQPPLSTPSTPVVESTHFKRDSSPSRPISNLTVEVTVPEEQQEGDATPKPKRDRSAVGPDSTPRVKIREPSRGPDSDDDVEELDQAASPEKPKKKARRGRRGGKNHRRGKKPDSEGESKDQADRVVDQVNNLQPQSRLEPDLQLVRTVSNDIIEMDGVLQIGRLRVFSDVVLGHGSHGTVVYRGSFDGRDVAVKRMLVEFYDIASHEVGLLQESDDHNNVIRYFCREQAAGFLYIALELCPASLQDLIERPGDYPQLVQGGLDMPDILRQIIAGVRYLHSLKIVHRDLKPQNILVAMPRGRTGSRSLRLLISDFGLCKKLDDNQSSFRATTAHAAGTSGWRAPELLVDDDNRSAIQGGESQHTESSEPAVVDPQTNRRATRAIDIFSLGCVFYYVLTRGSHPFDKNGKFMREANIVKGNFNLDELQRLGDYAFEADDLIRSMLSLDPRKRLAPLCSSLAFRLFTDLFPRPDASAVLMHPFFWNPSDRLSFLCDVSDHFEFEPRDPPSDALLCLESVACRVMGPEMDFLRLLPKDFKDNLGKQRKYTGSKMLDLLRALRNKRNHYNDMPAHLKAHIGGLPEGYLNFWTVRFPSLLMSCHSVIVELRLTKIDRFKRYFTPVE
What is the function of this protein?
Senses unfolded proteins in the lumen of the endoplasmic reticulum (ER) via its N-terminal domain which leads to enzyme auto-activation (By similarity).  The active endoribonuclease domain responds by cleaving an intron from the downstream cytoplasmic mRNA hacA, allowing for the translation of a transcription factor that coordinates a series of adaptive responses that are collectively known as the unfolded protein response (UPR) (PubMed:33087521).  In the absence of ER stress, ireA controls dual signaling circuits that are both hacA-dependent and hacA-independent and which contribute to the expression of traits that are essential for virulence (PubMed:22028661).
What are the official names of this protein?
Serine/threonine-protein kinase/endoribonuclease ireA, Endoplasmic reticulum-to-nucleus signaling A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: O51E1_HUMAN
Sequence: MVDPNGNESSATYFILIGLPGLEEAQFWLAFPLCSLYLIAVLGNLTIIYIVRTEHSLHEPMYIFLCMLSGIDILISTSSMPKMLAIFWFNSTTIQFDACLLQMFAIHSLSGMESTVLLAMAFDRYVAICHPLRHATVLTLPRVTKIGVAAVVRGAALMAPLPVFIKQLPFCRSNILSHSYCLHQDVMKLACDDIRVNVVYGLIVIISAIGLDSLLISFSYLLILKTVLGLTREAQAKAFGTCVSHVCAVFIFYVPFIGLSMVHRFSKRRDSPLPVILANIYLLVPPVLNPIVYGVKTKEIRQRILRLFHVATHASEP
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51E1, D-GPCR, G-protein coupled receptor 164, Olfactory receptor 52A3, Prostate-overexpressed G protein-coupled receptor, Prostate-specific G protein-coupled receptor 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: HSSS_STAAM
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTVDQKGHKTFYGEPFREDTLSQNAINNVLNNKDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVDQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSH
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTR17_ARATH
Sequence: MVNSNEEDERRILDVEESLLTQEEVNNHLTGLSSTAEDGSIDIYGNPPSKKKTGNWKACPFILGNECCERLAYYGIAKNLITYYTSELHESNVSAASDVMIWQGTCYITPLIGAVIADSYWGRYWTIASFSAIYFIGMALLTLSASLPVLKPAACAGVAAALCSPATTVQYAVFFTGLYLIALGTGGIKPCVSSFGADQFDDTDPRERVRKASFFNWFYFSINIGSFISSTLLVWVQENVGWGLGFLIPTVFMGVSIASFFIGTPLYRFQKPGGSPITRVCQVLVAAYRKLKLNLPEDISFLYETREKNSMIAGSRKIQHTDGYKFLDKAAVISEYESKSGAFSNPWKLCTVTQVEEVKTLIRMFPIWASGIVYSVLYSQISTLFVQQGRSMNRIIRSFEIPPASFGVFDTLIVLISIPIYDRFLVPFVRRFTGIPKGLTDLQRMGIGLFLSVLSIAAAAIVETVRLQLAQDFVAMSIFWQIPQYILMGIAEVFFFIGRVEFFYDESPDAMRSVCSALALLNTAVGSYLSSLILTLVAYFTALGGKDGWVPDDLNKGHLDYFFWLLVSLGLVNIPVYALICVKHTKKKAL
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 8.5, AtNPF8.5, Peptide transporter PTR6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PEX7_DICDI
Sequence: MKRFHSHFNGYSVEFSPFEEQRLACVTSQHFGIIGNGRQYILDVLDRDIGAFKTFDTRDGLYDCTWSEENECHVASSSGDGSIKIWDTQAPSGGRPIKSFEEHTKEVYSVDWNLVTKDTFITGSWDQSIKIWNPRMDRSLKTFREHRYCIYSAIWSPRNAHLFASVSGDRTLKIWDSRDNRSLNTIKAHDHEILTCDWNKYNDKEVVTGSVDKTIRIWDIRYPDRPTTILRGHTYAVRRIKCSPHSESMLASCSYDMSVIVWDRAREQDPIIARMDHHTEFVVGLDWNMFIDGQMASCSWDEQVCVWNLGRPGQFR
What is the function of this protein?
Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal.  Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol.  Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex.
What are the official names of this protein?
Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat peroxin-7 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: RECO_LEUMM
Sequence: MAIIRGIVLYTRQYKDNDLLVRILTETYGMRTFLARGAKKATSKLSAGTQPYTIVTFDGALPKRETGLGYMNDVQDIKVYSRLIEDIEANAYAALIASLIDASFEEGEKITRWYNQLYVALQKLDEGLDPQIIANIFEIQLLVPLGVAPNLRADPITGQVDGKFDYSEKYNGIISEHHFNLDDQRLMLDQKTVFYLRQFSVIDMRQVHDIKMSAITKRGLQRVIDYIYEKQVGLKPRAKSFIEQMHSWQNTLVNFRRNK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PPAE1_SPOLT
Sequence: MWKSLVFFVSALIWSFGSSQDCTTPTGSRSNCVSLYQCQPLYNAFEQRPLPTHVVSYLGRSQCGFEGYVPRVCCGPLPEEQEATSARPTQAPTQGSSDVFPEDSSPAPRNQCGIDTTGDRVYGGTITDLDEFPWMALLGYRTKKGTTSYQCGGVLVNHRYILTAAHCITGAIEQAVGTLITVRLGEYDTQQDVDCIDSVCADRPQEIRVASAYPHPGYSDKNKNRQDDIGIVRLATRAAYTYYVQPICLIDNRARLDTGSDVYVAGWGKTLNGRNSPIKLKLNLPIFNKQECDDKHRGEVLSSVQICAGGVFAEDACRGDSGGPLMKKTPNGIWEVVGVVSFGYGCGRDGWPGVYTSVARYIDWIQNTIASSNV
What is the function of this protein?
Serine protease which, by cleaving and activating prophenoloxidase (PPO1) after immune challenge, plays an essential role in the melanization immune response to wounding.
What are the official names of this protein?
Phenoloxidase-activating enzyme 1, Prophenoloxidase-activating enzyme 1, Serine protease PPAE1, Slppae1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: RF1_TREPA
Sequence: MIEKLEELRAQWRKLQQEVENPSLFSSTQSYRERMRDHAYLSRLMEEYDRYLLTEKQLEDAHVLIQDESDADFKDVIRQEIRTLEAALHTSQKRLKTLLIPPDSLQEKNIIMEIRGGTGGDEAALFAADLFRMYTHYAESKQWRYEVLAVSETELGGFKEITFSISGRDVYGSLRYESGVHRVQRVPSTEASGRIHTSAVTVAVLPEMEETEVDIRAEDVRVDVMRASGPGGQCVNTTDSAVRLTHLPTGIVVVCQDEKSQIKNKAKAMRVLRSRVYDLEESKRQVARARERKSQVGSGDRSERIRTYNFPQNRVTDHRVRVTLYKLDAVMQGALDDIIEPLCIASRESVI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHBO_MYCTU
Sequence: MPKSFYDAVGGAKTFDAIVSRFYAQVAEDEVLRRVYPEDDLAGAEERLRMFLEQYWGGPRTYSEQRGHPRLRMRHAPFRISLIERDAWLRCMHTAVASIDSETLDDEHRRELLDYLEMAAHSLVNSPF
What is the function of this protein?
When expressed in E. coli and M. smegmatis, HbO increases oxygen uptake.  Membrane vesicles of E. coli carrying HbO show a respiration activity about twice that of membranes without HbO.  HbO seems to interact with a terminal oxidase.  Therefore, HbO could participate in oxygen/electron-transfer process, suggesting a function related to the facilitation of oxygen transfer during aerobic metabolism of M. tuberculosis.
What are the official names of this protein?
Group 2 truncated hemoglobin GlbO, Hemoglobin-like protein HbO, Truncated hemoglobin, trHbO.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.