PharMolix/UniProtQA huggingface dataset:
Protein: IF2_STIAU
Sequence: MSKKRVHEIAKELKGHGIELDNKEVVTELAGLGYDVKSHSSSLDDDQATAAVQKILDKRKPKQAAAPVTAKGFVVRRKVGPPTGSGVYDASQEPSQAASDVSSPPSEPVHEASGAEAAASERVPEAAAVQEPVAEAPRAAASEPAAEAPKATAPVAPEPTVEAPKAAAPVAPEPTVEAPKTEAPVAAAPIAEAPTPPARTEVPVTSGRRAASCRGAAPLPCSGKDPLALNSSPQSSAAFCPDARNPGDCDFPSTSGRWHAWPSRGSSGRFAHGAGRPSGWTFARWTSGRPRAASRRTAVQRPSGRAGAGASHGLQRRKGFGAGAQASGQPQNVTMVGGIPHAPTAPDARALRPTATQAVVISRPLIQVRRVTPTTSSAKQYPMAPGKKAIGEVREFKVVPDHAGRGRELVDVSKNKDKSPRKRGGPNDTSISKQELTDLAWGRVNIPLRGKKKKPTKKGAKTQITQMAEDKKVIKLQEGISVSDLGQRMGVRTSDIIKKLMGLGKMATANQMVDADTVELIASDYGWKVDRVGFEVEDYLPEVVARPEDARTRPPVVTVMGHVDHGKTSLLDAIRAANVASGEAGGITQHIGAYSVTTARGDITFLDTPGHEAFTSMRARGANVTDIVILVVAADDGVMPQTIEAIKHAKAAEVPIVVALNKMDVPGANPDRVKKDLANHELVPEEWGGETIMVPVSAKQKMGIDLLLENVVLQAEVLELTSNPSRPAVGAIIEGELDRGRGPVATVLVQEGTLRVGDAVVTGTDYGRVRAMNNSRGESVKEVLPGYCAEVIGLSGVPSAGDTINVVADEKAAKQIAEHRGMKERQSELSKVSRETLDQLFAKTKAGGGPKELRVVIKADVQGSAEAVKQAVQKLTTHKVKVEVIDTGVGAITESDVMRAAASKGVVLGFNVKPESGAESAAKAEGVMLRSFSIIYELIDGVRSSMEELLEPIRTERKLGRAEVRNTFNVPKLGTIAGAAVLDGVIKRGAFVRLMRENKQLFAGKMASLRRFKDDVKEVAQGFECGIGIENFNDLKAGDIIEAYEIEETRQSLT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEGS_YERPN
Sequence: MPHTLLILNGKESGNPEVREAVKNVRDEGLTLHVRITWEHGDAKRYVEEAATLAVSTVIAGGGDGTINEVATALMSLPADKRPCLGILPLGTANDFATGCNIPLQIENALQLAVKGRAVAIDLAQVNGEHYFINMATGGFGTRITTETPDKLKAALGGVSYFIHGLMRLDALKADSCKIHGPDFHWSGDALVIGIGNGKQAGGGQLLCPDALINDGLMQLRLLTAKELLPAVLSTLFNGEKNKNVIDATVPWLDITAPNDITFNLDGEPLSGRHFHIEILPHAIQCRLPPNCPLLG
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3711_PSEPF
Sequence: MTTEFETRSDEPRLNATEIRILGSLIEKQATSPETYPLTLNALVLACNQKTSREPVMNLTQGQVGQSLRALESRGFAKLVMGSRADRWEHKVDKALELVPAQLILTGLMFLRGPQTVNELLTRSGRMHEFEDAEQVVHQLERLIARELAVLIPRQAGQREDRYTHALGDPADIEAIIAARQNPSDRGAASGVSVERIEELEARIAALEERLARLEE
What are the official names of this protein?
UPF0502 protein Pfl01_3711.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: COBQ_LIMRJ
Sequence: MTVQSIMFQGTASDAGKSWLAAAVCRILANRGQKVAPFKSQNMALNSFITEKGDEMGRAQVFQAEAAKVKPDVRMNPILLKPSTDKDSQVIVMGKVLKNMDAVSYYQFKRELIPQIMMAYNTLADENDVIVLEGAGSPAEINLNENDIVNMGMARMADAPVILVADIDKGGVFASIYGTIKLMPREDQQRIKGIIINKFRGDKSLLESGNKMIEKLTGIPVIGVLPMSSIDIDEEDSVSLIRKPRQKDTQKDLDVAVIDLDKISNFTDIHSLEIQPDVSVRYVLTAEELGTPDLLIIPGSKNTNADLVALRKNGIAEGILRAHKDGSMIVGICGGYQILGQMLYDPTGIESPIKEQKGLGLLDTETTFNEKKTTTQAVAKRNNYILKGYEIHMGTTKRGLNSTPFSTIQETNGQPENREDGAVSTDGTVIGTYLHGIFDNPYWTRHLLNQLRVAKGMAPLVDTTVSISGYKDQQYEKLAQLFAQNVDMDKFNQILQDSTKE
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: ALG8_COCIM
Sequence: MAEFFPSLTQCALVAAAFKVLLFPAYKSTDFEVHRNWLAITHSLPVQDWYYEKTSEWTLDYPPFFAGLEWLLSKVAFFVDPAMLQLGNLNYDSWQTIYFQRSSVIFLELMLVYALNRYIKSVPAPSKHLAHAASLSILLSPGLLIIDHIHFQYNGFLYGILILSIVLARKQSTLLYSGVTFAILLCLKHIYLYLSLAYFVYLLRAYCLDPNSVFRPRFGNIIKLGIGVTSVFAAAFGPFVYWGQLNQIKERLFPFSRGLCHAYWAPNIWAMYSFVDRVLIPVAPRLGLPIKADALTSVTRGLVGDTSFAILPEVKKEHTFALTLFFQLLPLLKLWLQPNWDNFVGSITLCAYAAFLFGWHVHEKAILLIILPFSLLALKDLRYLGAFRPLAVAGHVSLFPLLFTAAEFPVKTVYTVLWLVLFLFTFERLAPVPARPRVFLLDRFSLLYDTVSIPLIVYCSLVHGWLFGGRMEFLPLMFTSSYAALGVVGSWVGFMVVYFTS
What is the function of this protein?
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 8, Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: 3SIY3_DENAN
Sequence: LTCVTGKSIGGISTEECAAGQKICFKKWTKMGPKLYDVSRGCTATCPKADEYGCVKCCKTDRN
What is the function of this protein?
This protein shows a synergetic toxic effect in that it enhances the toxicity of other toxins.
What are the official names of this protein?
Synergistic-type venom protein C9S3, chain 1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSIE_SALEP
Sequence: MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLADALFVPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLIIVDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TARK_STAA8
Sequence: MKIDGNTFICRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAYAALNEEQIEEYNELTTQNGKVNYLLAYDAKVFRKGGVSQHTVYTITPEIASDVNEFVFDIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFTSDSRPNLSGNFKYVYDELLRQKVDFDYDIKTVFKENITDRRKWRDKFRLPYLLGKADYIFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKHNAVVLFKMHPFVKNRLNISREHRQYFIDVSDHREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPFESFVPGKIVQSFDALMDALDNEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR
What is the function of this protein?
Can catalyze the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit.
What are the official names of this protein?
Teichoic acid ribitol-phosphate polymerase TarK, Poly(ribitol phosphate) polymerase TarK, Ribitol-phosphate polymerase TarK, Tar polymerase TarK.
What is the protein family that this protein belongs to?
Belongs to the CDP-glycerol glycerophosphotransferase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYN1_MOUSE
Sequence: MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSATASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQPQRDASPGRGSHSQSSSPGALTLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPVTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGAPQATRQASISGPAPTKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPAKPQLAQKPSQDVPPPITAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD
What is the function of this protein?
Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton.  Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (By similarity).  Also involved in the regulation of axon outgrowth and synaptogenesis (PubMed:7568107).  The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxide functions at a presynaptic level (By similarity).
What are the official names of this protein?
Synapsin-1, Synapsin I.
What is the protein family that this protein belongs to?
Belongs to the synapsin family.
What are the subcellular locations of this protein?
Synapse. Golgi apparatus.
Protein: SELO_PELUB
Sequence: MTIGWHFDNSYSRLPKTFKENINPVAVNAPEILILNKDLANKLDLDFSNINDDDLSKIFSGNLLPEGSNSIAQAYAGHQFGHFTMLGDGRAVLIGEHLTKNNERFDIQFKGSGRTPFSRSGDGRAVLGPMLREYIISEAMHFLKIPTTRSLAVVKTGEDVVREQISQGAILTRVALGHLRVGTFQYIAAKQNISDLEILINYTIEKYYPNIKSSKNKALDLLNVLIEKQTQLVIDWMRVGFIHGVMNTDNMSISGETIDYGPCAFMDVYDPKTVFSSIDQLGRYAYENQPKITKWNLTRFAECLIPLISTNEDEAIKLATEALDKFEQNYETKWLNMMRDKLGLYGEDKEDKNLIMELLNWMKEKKADYTNTFIFLMNKTIKNSEVYDNADFDLWKTKWMKRLVMFGNTHDKSVDLMSSCNPMVIPRNHKIEEALMLANNGDLTLFNKLIKILKNPYLVNNGDLELMSPAPHSDEKYQTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ROA2_MOUSE
Sequence: MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGSYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles.  The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting.  Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs.  Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.  Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm (By similarity).  Specifically binds single-stranded telomeric DNA sequences, protecting telomeric DNA repeat against endonuclease digestion (By similarity).  Also binds other RNA molecules, such as primary miRNA (pri-miRNAs): acts as a nuclear 'reader' of the N6-methyladenosine (m6A) mark by specifically recognizing and binding a subset of nuclear m6A-containing pri-miRNAs.  Binding to m6A-containing pri-miRNAs promotes pri-miRNA processing by enhancing binding of DGCR8 to pri-miRNA transcripts.  Involved in miRNA sorting into exosomes following sumoylation, possibly by binding (m6A)-containing pre-miRNAs.  Acts as a regulator of efficiency of mRNA splicing, possibly by binding to m6A-containing pre-mRNAs (By similarity).  Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).  Also plays a role in the activation of the innate immune response.  Mechanistically, senses the presence of viral DNA in the nucleus, homodimerizes and is demethylated by JMJD6.  In turn, translocates to the cytoplasm where it activates the TBK1-IRF3 pathway, leading to interferon alpha/beta production (PubMed:31320558).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2/B1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm. Cytoplasmic granule. Secreted, extracellular exosome. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Not found in the nucleolus. Found in exosomes following sumoylation.
Protein: GATC_ENTFA
Sequence: MAITEEQVKHVAKLSKLSFSEEELADFTNQLDKIIDMVELLEEVDTTGVPFTSNVNESINVMREDVATPGMDRKELMRNVPESENGYIKVPAIMDNGEAGA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MP1_TCV
Sequence: MDPERIPYNSLSDSDATGKRKKGGEKSAKKRLVASHAASSVLNKKRNEGSASHGGTWVIVADKVEVSINFNF
What is the function of this protein?
Cell-to-cell movement.  Displays RNA-binding activity (By similarity).
What are the official names of this protein?
Double gene block protein 1, DGBp1, Movement protein P8.
What is the protein family that this protein belongs to?
Belongs to the carmovirus double gene block protein 1 family.
Protein: ACPS_YERPG
Sequence: MAILGLGTDIVEISRIQAVVERTGERLARRILSPSEWQHYQQHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVVNDALGKPTLRLHSRAAELAVELGVKSLHVTLADERRYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BREVE
Sequence: CVPKRKVSPSXRNMRXAHDXLT
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NFYA2_CAEEL
Sequence: MNPRGNPSKMPTQIVLNRRPAAPARPQTTFTSLSQYHMYNTASTSSAPPPPPNQNFGQIREAIRTTQPTTVQLPPDCKLVEYTWQENGESRTVLIPMSNDSTEDDVRSALPQSVLESINQHQNQLRQGNAQAVHYYQKHQNPISHEKPIMVNPRQYKRIIKRREMRQKMEDSGRLPLERQKYMHESRRQHALKRRRTGGRFDANAEAAAASSEPSISSAAPSPPKAPRAPTTYAMIRPATSHPPVNIPKAPAMTYRPVQEEKKSIERISKAQMFTIPKRQQ
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (nfya-2-NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes to regulate their expression and control cellular identity in particular tissue types (PubMed:17574230).  In association with the components in the nfya-2-NF-Y complex, may repress the expression of the T-box transcription factor tbx-2 throughout larval development, which most likely restricts its expression to certain tissues (PubMed:23933492).
What are the official names of this protein?
Nuclear transcription factor Y subunit nfya-2, CAAT box DNA-binding protein subunit nfya-2.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_CLOB8
Sequence: MIGLIGIRKNTPLEIREKFIVKSKKYNEYFGELLKELNEVVILATCNRTEIYFNASLNEEELLKKIFDIFNWDYEYKKYVFITNNKDAYRHLFEVCSGFHSKILGEDQILGQVKDAYEEALEFKAVSLELHRLFQEAITCGKRFRKEAKLFEIPVSSSSIVVSEAIKRECTKFMVLGYGEVGQLVMKYLLSHKIQTVYLVVRNPKIKDEIQDERVKVITFEEKNKYINSIECIISCTSAPHPVVKTEDISESGSRLVIYDLSVPRDVEKEVALLSRTEVYNIDTISRIDDENKKLRKDKMEDNRHIMNKYLKEYDEWLKLRSISHVIKNLKTVGNDVYEKRVQTFSHKSKDKNDIALAHKLIKSTSDFYINRAIEVIKEETLKGCGEEWIGIIEKIFMTKE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HISX_COLP3
Sequence: MINQLINWQELSPQQKNSALARPAIADSALLSTQVANILSQVKNQGDKAILALTEQFDGIALSTLSVSSAQVAQAKLALTDKRLKAIHTAYKQIKSFHSAQTASDITVETTPGVKCTLKTEAIESVGLYIPAGSAPLPSTVLMLGVPAQLTGCQRTVLVCPPDKNGQLADEILVAADLCGITEIYTVGGAQAIAALAYGTETIPAVNKVFGPGNRYVTEAKTQLSQQVAGFAIDMPAGPSEVLVIADGQANPAFIAADLLSQAEHGVDSQVILLSDSESLISKVSTEIAQQLTLLSRCKIAEQALKQSRLILTKDLAQAVEVSNEYGPEHLIIQTEDAPTLLSKLRNAGSIFVGAYTPESAGDYASGTNHVLPTYGYSKVISSLSLADFSRRFTVQEITKAGLQSLAECIIELTDAEGLDAHQRAVTIRLEEGS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: VF312_ASFM2
Sequence: MLLVKMTTTIFYADDLLQALQQAKAEKNFSSVFSLDWDKLRIAKRNTSVKYVTVNVTVKGKKAPLMFSFQNEKHVGTIPPSTDEEVIRMNAENPKFLVKRRDRDPCLQFNKYKISPPLEDDGLTVKKNEQGEEIYPGDEEKSKLFQIIELLEEAFEDAVQKGPETMKTKNIIKLVQRKISSSAIKNADKPLPNPIARIRIKVNPTTTMLAPILLDKNKPITLQNGKTSFEELKDEDGTKANPDNIHKLIESHSIHDGIINARSICISNMGISFPLCLEMGVVKVFEKNNGIDVDSIYGSDDITNLINQVAIA
What are the official names of this protein?
Uncharacterized protein CP312R, pCP312R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP312R family.
What are the subcellular locations of this protein?
Virion.
Protein: HFLD_CROS8
Sequence: MAKNFYDITLALAGICQSARLVQSLAHEGTCDSEALHVSLKSVIDQNPASTLDVFGGREAGLKIGLETLLGMLNTSSRQGLGAELTRYTLSLMVLERKLAASKGAMNTLGNRIADLSRQLEHFELESDTLMSAMAGIYVDVISPLGPRIQVNGSPNVLQSPQIQAKVRATLLAGIRAAVLWQQVGGGRLQLMFSRNRLTTQAKQILAQC
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYS_XYLFM
Sequence: MLDPTLLRQQLAKLAECLLTVRGFTLDVAALEALESERKRIQVHTQELQSLRNSKSKAIGQARSKGEDVSALMAEVAAFSDDLKASEIALEEIRTELEKVALDIPNLPQQDVPLGADERENVEQARWGVPRTFDFAIKDHVELGACHGWLDAESAAKLSGARFTVLRGPIARLHRALAQCMLDLHVSQHGYEEVNVPIIVNADSLHGTGQLPKFEEDMFSTQLGEHRRYLISTSEISLTNLVRNEIIEADRLPLRMVAHSLCFRSEAGSGGRDTRGMIRQHQFEKVELVSVCKPQESEGEHHRMTRCAETVLEMLGLPYRKILLCTGDMGFAATKTYDLEVWLPSQGMYREISSCSNCGDFQARRMQARWRNSVTGKPELVHTLNGSGVAVGRAMIAVMENYQNADGSITVPEVLRPYMDGLSRIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_DEIRA
Sequence: MNPERFTEASAVAINAAQQLAQENHNQNLTHFHVLRTLLDNDTASRALTLAGGDLNTARAALDAEIAKLPKVQGSDGQLYLDPALNRAFQKADTLAAQLGDSFVAADTLLLALRGEYRGRGLPDEVSLNRAVTEQRKGKTVTNKTSEQQFDALNKYGTDLTQRARDGKFDPVIGRDEEIRRVMQILLRRSKNNPVLIGEPGVGKTAIAEGLAMRIVKGDVPEGLRDKKIVSLEMGSLLAGAKFRGEFEERLKGVIDEVVKSAGEIILFVDEIHTIVGAGKTEGSPDAGNMLKPALARGELHLIGATTLDEYREIEKDAALERRFQPVFVDEPSVEDTISILRGIKERYQVHHNVEITDPALVAAATLSNRYITDRQLPDKAIDLIDESAARLRMALESSPERIDQLSRRKLQLEIEREALKREKDVDSQNRLLDIENQLKTLTDELNEVRSRWEAERGEVAALREKREKLDAVRTQIEKARRDYDLEEAARLEYGELPALEKDVQDLEKKLKSAEFAHMEVTEEDIAAVVSRWTGIPVSKLMEGEREKLLHLEEQLHGRVIGQDRAIVSVSDAIRRARAGLNDPNRPLGSFMFLGPSGVGKTELAKALAEFLFDSSDAMVRIDMSEYMEKHTVARLIGAPPGYVGFEEGGQLTEAVRRRPYAVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNIGSPLILEMQQRGEDAETIKSAVMDELRGEFRPEFLNRVDDIIVFDALTAKDLQSIVDIQLGGLRRRLAERRITLHLTEDAKDKLAELGYDPAYGARPLRRTISQYIETPLAREILGGQIQDGSVLNVDYGDGGFTFNSGSLN
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y810_PYRAR
Sequence: MQIRWYGHAAFMVETGGAKLLIDPWITNPLSPASPQEVINAKPTHILITHDHFDHLGESVDIAKATGAPIVGSFELMLEVAEKGIPEAQTMPMNIGGTIKLGDGVEVYMTPALHTANRGAPSGFVVATPEGTVYHAGDTALFRDMELIGELYDIDVALLPIGSVYTMGPREAAIAVQLLRPRRVVPMHYNTFPLIRQDPEDFKARVEAVSRAKVFVMKPGDVLKL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Pars_0810.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RUVB_ALKEH
Sequence: MNDRLITPDASGEDEAIDRAIRPRRLTDYIGQPVVREQMEIFVHAARGRGEALDHTLIFGPPGLGKTTLAHIIANEMGVSMRQTSGPVLDKPGDLAALLTNLEPHDVLFVDEIHRLSAVVEEVLYPAMEDFQIDIMIGEGPAARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEYYNVADLSGIVKRSAHLLNLSIDETGCQEIAGRARGTPRIANRLLRRVRDYAEVRADGHISGEVAHAAMELLNVDRNGFDEQDRRLLLAIMEKFDGGPVGLDSIAAAIGEERGTIEDVVEPYLIQQGYLMRTPRGRMATRNAWLHFGLNPPRQPDTSPDLFQDAPPVGRER
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TPIS_TREDE
Sequence: MKKFYIAANWKMNMNRAEAKQLATEMKAGLKDGKNKYMIAPSFTLLQDVASVLKGSNILLGAQNMGLEEKGAHTGEVSVLQLLDVGVQAVILGHSERRHIYKETDDLINKKVKLALKHGLEVILCVGELLEEREAGHAEAVCERQIKKGLAEVSAKDLDKVTIAYEPVWAIGTGKNASPEDADAIHSSIRKTLAALYGEKAAKNMIIQYGGSMKPENAAGLLKKHNIDGGLIGGAGLKTETFLPIALFSE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.