PharMolix/UniProtQA huggingface dataset:
Protein: CP1A1_CAVPO
Sequence: MSTSAMELLLTATIFCLVLWVVRIFRPQVPKGLKSPPGPWGWPLIGHMLTLGKNPHLALTRLSARYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYSFTFISDGQSMTFNPDSGPVWAARRRLAQSALKSFSVASDPASVSSCYLEEHVKKEAEYLIKKFQELMAGPGHFDPYRYVVVSVANVISAICFGQRYSHDDQQLLELIDLNNEFGEVTGSGNPSDFIPILRYLPSATMDTFKDLNRRFSVFIQKMIKEHYKTFEKGHIRDITDSLIEHCQDRKLDKNANIQISDQKIIGIVLDLFGAGFDTITTAISWSLLYLVMNPRIQKKIQEELDTVIGRERQPQLADRPKLPYMEAFISEVFRYSSFMPFTIPHSTTKDTSLNGFYIPKGCCIFVNQWQINHDQKLWGDPSVFRPERFLSPDGTVDKALSEKVTIFGLGKRRCLGEVIGRWEVFLFLAILLQQLEFSTSPGVKIDMTPIYGLTMKYSRCEHFQAQTRPFVLKCPEA
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon-hydrogen bonds.  Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions.  Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation.  Catalyzes the epoxidation of double bonds of certain PUFA.  Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system.  Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer.  May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues.  Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid.  May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm.
Protein: IAA10_ORYSJ
Sequence: MRGGVAGPTAGEPPGTEAEAEEVEESSAGDDEELELGLSLGSKKQQQQQHAPCRILTARDLQPAAALSPDSSVSSSSPAAAAAAGGKRAEGPTATTSPGTVASGHPHSSFGVVGWPPIRQFRMNSLFNQAKENTSETDTKKTATNESDVQKDKEEGEKKGRVAGWVKVNMDGEVIGRKVDLNAHRSYKTLALALELMFTKPSIGLCASHNTNSLKLLDNSAEYQLTYEDRDGDWMLVGDVPWEMFVSSVKRLRIMRTSDANGLGQRYQGIHRTIASTRGRS
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA10, Indoleacetic acid-induced protein 10.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECX_CHRSD
Sequence: MSTQEATPRDDAIRLLARRDYSRSELMSRLAARGHAPDDIASLLDALADEGLQSDARFAEQFVRSRLSRGQGAMKIRAELGARGVTDEVAREALEGEAPDWHRLACEALAKRFDSPGRDPRERAKRERFLASRGFDFEQVRHAMAHAWENTR
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAE1_PICST
Sequence: MGCSNCQPEIKTSLHSKDSNDFEDDVWGDDDVYVDANADVKRAHQKQGYLDGLASAQESSLQSGFDKAFSDGARMGAAVGKILGELRALGESESFYQATKELNIAKIMDKKYFDSELKIQKNHEVIYKWQKIVAQHLEDATKA
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein YAE1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2851_SHESH
Sequence: MFGKGGMGNLMKQAQQMQDKMAKVQEEIARMEVTGEAGAGLVKVTMTGSHSVRKVDIDPSLLEDDKEMLEDLIAAACNDAARRVEENQKERMAEVTGGMQLPPGMKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Ssed_2851.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y1279_METJA
Sequence: MVILMDKRFIELIKKGWKLKNEENKATYIDEVFLGAIITTLTDNGYVLMDIASNGNFHYFMFEHLESWDRIKIVAEVLPHSLTDVKVIGARMFIEFSYGVMIKGIPPSLFGLGLKGYLSQMLSNIGSIRYEYDGYYTFVNCATYLLINDYIDFDTLTIDWEKLNNDINAIISSLAKYLEIHKKVE
What are the official names of this protein?
Uncharacterized protein MJ1279.
Protein: SYE1_NOVAD
Sequence: MATVTRFAPSPTGKLHVGNVRTALHNWLLAKKTGGRFLLRIDDTDAERSREEYVESIRADLQWLGLIPDGEERQSLRTELYEREFQRLVEAGRIYRAYETAQELDLKRKILLGRGLPPIYDRAALKLTEADHAAKAAAGERPHWRFLLDHDQPITWDDGIRGPQSFDPRQMSDPVIRRADGSWLYMLPSAIDDIAMGITDVLRGEDHVSNTATQIQMFTALGAEPPRFAHEALLTGSEGKLSKRLGALGMADFREQGIEPEAIVALLARLGTSDPVDAALDAAALATSFDLSRFGRAPARFDEADLHRVNAQIVHRLPYARVAHLLPQGMGEAAWEAIRPNLAHIDEARDWWNVVTGPVTAPTFDDETRAFLAQAAKTAASLDWSADPWRALTATLKDGTGRKGKALFLPLRQALTGHDHGPEMAALLPLIAQDEAVRRLSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1405_GEOKA
Sequence: MIVTTTNTIEGKEIEEYLGIVAGEVILGANVVRDFLASITDIIGGRSGTYESKLAEGREMAIKEMVNKARSLGANAVIGVDLDFETLRDGMMMCIATGTAVRLKS
What are the official names of this protein?
UPF0145 protein GK1405.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: Y943_MYCTO
Sequence: MAGVSEAERRGHRKLVRFQARRAIGPIRPTSAAWDRDFDPAGKRIAVVGTDAAAAHYISRLSESAASVTVFTQAPRRVVTGVPLWTTRAKRWLRRRTGAEHPAVAWATAAIDALTSSGIRTSDGVEHPVDAIIYGTGFAIADQVGDQTLVGAGGVTIRQAWDDGMEPYLGVAVHGFPNYFFITGPDTAAQARCVVECMKLMERTASRRIEVRRSSQQVFNERAQLKPAQPHRQTGGLEAFDLSSAATEDDQTYDGAATLTLAGARFRVRVRLTGHLDPIDGNYHWQGTVFDSLPETSLTHARAATLTIGGRSAPARITEQTPWGTHSVAGVGPPPYARSGPASATT
What are the official names of this protein?
Uncharacterized protein MT0969.
Protein: SYA_BRASB
Sequence: MSGVNEIRSTFLNFFAANGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGVEKRPYHRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKENAIELAWKLVTKEFGLPKDKLTATVYIDDDEAFGLWKKIAGLPESRIIRIAGSDNFWQMGDTGPCGPCSEIFYDHGDKVWGGPPGSPEADGDRFIEIWNLVFMQYEQLEGGVRNPLPKPSIDTGAGLERVAAVLQGKHDNYDIDLFVALIRAIADLTNADPQGPQKASLRVIADHLRASSFLISDGVLPSNEGRGYVLRRIMRRAMRHAQLLGAREPLMHKLVGALTREMGQAYPELIRAEALIKETLRLEETRFRKTLERGLAILDEKSSTLKKGDMFDGDVAFTLYDTYGFPLDLTQDALKSRGISVDQASFTDAMERQRAKARAAWAGSGEAATENVWFPLREKLGATEFLGYETETAEGAVTALVKDGAEVEGLKAGESGAIVLNQTPFYGESGGQVGDTGVMSGDGVRVRITDTQKKAGDLFVHIGTVEQGTLKLGAALQLEVDHGRRSAIRANHSATHILHEALRQVLGDHIAQRGSLVSPDRLRFDFAHPKPISAEELARVEDIANDVVLENAEVTTRLMALDDAREAGARALFGEKYGDEVRVVSMGNAARDQASNAQASNAMGWSVELCGGTHVKRTGDIGLIAVTSESAVSSGVRRIEALTARGARAHANHNLSLAKAAAAELRTTVDEVPARIAALMEERKKLERELSDARKKLAMGGGAAAGGSASGIREVAGVKLMARAVEGVEMKDLKSLVDEAKKQLGSGVVAIVGRAEDGKAGVVVGVTADLTARFNAVELVRAASEALGGKGGGGRPDMAQAGGPDGSKAEAALAAIESAISRAG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II, HNTX-II, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: M3K20_MOUSE
Sequence: MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTNLPDQCNSFLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYFWVQQLVRKGESSVEMSGYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYLNLFHFPPLIKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEVAITYIKDVTFNTSLPDAEILKMTKPPFVMEKWIVGIAEDQTVECTVTYENDVRTPKLTKHVHSIQWDRTKPQDEVKAVQLAIQTLFSSSEGNPGSRSDSSADCQWLDTLRMRQIASHTSLQRSQSNPILGSPFFPYFANQDSYAAAVRRTQTPVKYQQITPSINPSRSSSPTQYGLSRNFSSLNLSSRDSGFSSLNDSSSERGRYSDRSRNKYYRGSVSLNSSPKGRYGGKSQHSTPSRERYSGKFYRLPQSALNTHQSPDFKRSPNDHDRRVPRTIPGMPLHPETASKAGEEESRVSEGGWTKVEYRKKTHRQLSAKTSKERTRGNYRGRRNF
What is the function of this protein?
Isoform that lacks the C-terminal region that mediates ribosome-binding: does not act as a sensor of ribosome collisions in response to ribotoxic stress.  May act as an antagonist of isoform ZAKalpha: interacts with isoform ZAKalpha, leading to decrease the expression of isoform ZAKalpha.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 20, Leucine zipper- and sterile alpha motif kinase ZAK, Leucine zipper- and sterile alpha motif-containing kinase, MLK-like mitogen-activated protein triple kinase, Mitogen-activated protein kinase kinase kinase MLT, Mixed lineage kinase-related kinase, MLK-related kinase, MRK, Sterile alpha motif- and leucine zipper-containing kinase AZK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Appears to shuttle between nucleus and cytoplasm.
Protein: LEF7_NPVOP
Sequence: MEPPLKRCRLCHQALPKLPQLPFEMIDKILSHLPFDLHVDVVGASAATRLRALRRPDRLTRYHEYDLAADELFAAHWNIEAADPARPYVGQLCRSTCASAAQKFFNERVPRAAAMCMLNAPRAESDSVLTRRWNWWGLTRTLLIHEANSGRGRRPARVRVDADEACIGYHAPFCDASVFEFNAQPDHVVFVLLDDDKIELNMYGKRVYRIV
What is the function of this protein?
Involved in late/very late gene activation.
What are the official names of this protein?
Late expression factor 7.
Protein: LIS1_PHATC
Sequence: MVLTDRQRADLHAGIYEYLQSRGDAYQKVVEALAQADPECTIPHTTTTSNGSSAGLTKTPLLEKKWTAIPRLQKKVLELERQASHHAKIHAHRSAAGSGGGALEANDGAGGARRLLPRLPCQHTLQGHSSVVTCVRVHPVFTVVVSGSEDGSVKVWDHESGEYIRTLKGHTNTVNGLAFTPTGSHLASCSTDLSIKLWDFQTYACIKTLRGHDHTISSVVFLPFGGDLLTTTKCKRLLSASRDCTVKVWDLETGFCDQTIHDHNDWVRTLATRADGSVWASAGNDTVIYVYEQDRMKKAVELRGHEQVVESIAFLTQDTIPKNNAQRPSKHIETVRDYLVSGSRDRTVRLWKVSEASCLMVLKAHDNWVRSVLIHPNGNYILSSSDDKSIRVFDIKNERCLRTLENAHNHFVSSLDMHATLPILVSGSVDQTIRCWPLD
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: RL24E_HALMA
Sequence: MPRTRECDYCGTDIEPGTGTMFVHKDGATTHFCSSKCENNADLGREARNLEWTDTARGEAGEAEDEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e, Hl21/Hl22.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: ARGP_PROMH
Sequence: MKRPDYRALQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENLFGQPLLVRTVPPQPTEQGQKLLALLHQVEMLEEQWLGDENSGSTPLLLSLAVNADSLATWLLPALHPVLTQLPIRLNIQVEDETRTQERLRRGEVVGAISIQPQALPSCLVDQLGALDYLFVASPDFAQRYFANGVTKSSLLKAPAVAFDHLDDMHQAFLQQNFGLSPGSVPCHIVNSSEAFVQLAKQGSTCCMIPHLQIADELKSGELIDLTPGLCQRRMLYWHRFAPESRTMRKVTDALLDYGRKVLKQDEE
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PANC_GLUOX
Sequence: MQVFETIGAFRAALTAYPTLGFVPTMGFLHEGHLGLVRRAKAENGAVAVSIFVNPTQFGPNEDYASYPRDPDRDLALLKEAGADLVFLPTPDVLYPPGAVTRIEVGGVANELEGQSRPGHFSGVATVVTKLFNIVQPQRAYFGQKDAQQCAVVRRFVADLDIPVEIVVCDIAREADGLARSSRNVRLTAENRQKAPALFQALQETAGLFRNGERDVDILENAMRAVLTEAGLLDIDYATVVNADTFRREQPCSDNALALLAVQAGEVRLIDNMPL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_MYXXD
Sequence: MPLSPDPYSALRHAAKYVQQFRRKTFVVKLGGAMLSDPRLRRAACEQIALLWTFSIRPVVVHGGGPELDTLCDALHLPVEKVAGRRVTSAPVLDAAKMVLAGKLHTDLLADLQAAGVPAVGLSGVDAGLIKARKRPPVMVTEAGATEGKLVDYGLVGDIEQVDTRVVEHLRSADYVPVIAPLSGGTDGAVYNTNADTVAAALAVALSAEKLFFLVQVPGLLKNVSDPSSLVTLANLTDLATMESTGAIAGGMKPKAHAIRHALVGGVGSVHLVSGVQPNALLEEVFTNEGSGTMVVRENAQKPAGAVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTNK_PSEF5
Sequence: MTISNPRPLLGCIADDFTGATDLANMLVRGGMRTVQSIGIPSAEVAAGLDADAVVIALKSRTTAASEAVAESLAALQWLRDQGCEQIFFKYCSTFDSTAAGNIGQVSEALLEALGSDFTLACPAFPENGRTIFRGHLFVQDQLLSESGMQHHPLTPMTDANLVRVLQSQTRLPVGLLRYDSIAQGVEAVRSRIAELRGQGVALAIADALSDADLYTLGAACADLPLLTGGSGLALGLPENFRRAGKLRDLDAASLPKVAGGEVVLAGSASLATNAQVDAWLEAERPAWRIDPLALAAGEAVVEQALAFAREQQGTVLIYATSTPEEVKAVQRQLGAERAGALVENALGEIARGLRDSGVRRFVVAGGETSGAVVKALDVRLLQIGAQIDPGVPATVSSGGEPLALALKSGNFGGRDFFSKALGQLAGGQA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.
What are the official names of this protein?
3-oxo-tetronate kinase, 3-dehydrotetronate 4-kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: SYR_TREPA
Sequence: MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSPAQLAQQLCTLLEEDTSMCAYGTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYLQGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCGADVFKVNIINDRGVHICKSMCAYQKFAHGKTPAHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVRALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIWVDLSSLGLDKKALLRSDGTTMYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFVLRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDILDRLHSAAEEEIAKKGRENALKHAQCIAENVAIAALHYFLLQVSPQKDMVFHPEESLSFNGNTGPYLQYMGARISSLLKKVQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSKSFSRFYHDCPILCEARPDYACARLELVRAVRIVLRTAMRLVLIPFLEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SALG2
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MNMA_UREP2
Sequence: MEVKVKKRVVVGLSGGVDSSVSALLLKQEGYEVIGLFMSNWDTIANFENNHEFNKTHQGCESELDYQDAQAVAQKIGIPLYRVEFIKEYWDNVFEYFLSEYQKNRTPNPDILCNQFIKFDSFLNYAKNELQADYIAMGHYARVKHDRNSSFLLKAIDTNKDQTYFLCNLNQNQLQNVLFPIGHLTKLQVRAIAKKHGLITANKKDSTGICFIGERNFKTFLQNYIPNQPGQIINIVNNQIIGHHIGTMYYTIGQRKGLNLGGMNERMFVCDKDIDKKIIYVAPSSFEKQYLISTQALIENINFIEPYNPQIPIMVRFRHRQDLIIVNDFLPIKNTKNVLINYESARAITPGQYAVFYQNDHCIGGGIVSKTNIGHQKVDFLVYKS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CALS8
Sequence: MSKVTKKVEELVKPILEKYGFDLVDIEFKKEGKKHFLRVYIDKPGGITIDDCQLVSEELSNKLDIVDPIPFSYYLEVSSPGVDRPLVNDRDFIRNKGRVVDVFLKQPIMNTTKLTGELVEKNEDVLIIMIDGENISIPFENVKKVKVAIRF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_HALH5
Sequence: MGTIVKNVSIVTGQAEAPFIRHGYFKFADGVIVSVAEGTPSPEEIDRVEVIDGKGKWVMPGMINTHGHLGMSLLRGHSDDLPLQSWLTEKMWPFEGKMDREAVHHARQLAMAEMIKSGTTTFLEMYHLYMDDLAEAVVEQGPRAVLMRSMIGLCSESEQREKLKEAVTFATTWNGDGNGRITTMMAPHAPYTCPPSFIEMIVDEADRIDLPLHTHMAETQREVEEHRKTYGVHPLVHFEQLGFLKDRHWLLAHCVHLGEEELDILEQHPSVHVSHNPMSNLKLGSGIANVQSMLERGINICLGTDSVASNNHLDLVEEMRIAALLQKGAVLDPTAIPAETAIAMATKNGAKALRLPQVGTIEAGKRADFIMIDPQCLHLQPHEHVMSHLVYALKGADVQDVFVEGAPLMLNKELKTFDEEKLQFEANAHYQRICEKLK
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: VP4_ROTH7
Sequence: MASLYRQLLSNSYVTNISDEVSEIGARKTTNVTVNPGPFAQTGHAPVNWGHGELSDSTLVQPTLDGPYQPTTFNLPIDYWMLIAPTQIGRVAEGTNTTDRWFACVLVEPSVSNTQREYVLDGQTVQLQVSNDSSTLWKFILFIKLGKNGTYSQYSTLSTSNKLCAWMKREGRVYWYAGTTPNASDSYYLTINNDNSNVSCDAEFYLIPRSQTDLCAQYINNGLPPIQNTRNIVPVSISSREIRHTRAQMNEDIVVSKTSLWKEMQYNRDITIRFKFANSIVKSGGLGYKWSEISFKPMNYQYTYTRDGEEITAHTTCSVNGVNDFSYNGGTLPTDFAISRFEVIKENSYVYIDYWDDSQAFRNIVYVRSLSANLNDVICSGGDYSFALPVGAYPVMSGGAVTLSPAGVTLSTQFTDYVSLNSLRFRFRLAVSEPSFSISRTRLSGIYGLPAANPNNNVEYYEIAGRFSLISLVPTNDDYQTPIANSVTVRQDLERQLGELREEFNSLSQEIALSQLIDLATLPLDMFSMFSGIKSTVEAVKSMTTNIMKKFKTSNLANAISDLTNSMSDAASSISRSTSIRSVGSNTTMRISTAIQTGEDLKTMADASTQISNVSRSLRLREFTTQTDNLSFDDISAAVLKTKLDKSTQISQNTIPDIISESSEKFIPMRAYRVMDNDTAFETGIDGTFYAYRVDTFDEVPFDVEKFNKLITDSPVLSAIIDFKTLKNLNDNYGITKTQAMELLQSNPRTLKEFINNNNPIIRNRVENLIAQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: CH60_KORVE
Sequence: MAKQIVHGEESRQSILRGVNVLADAVKVTLGPKGRNVVIDKKFGSPLITKDGVTVAKEIELKDTLENMGAQMVKEVASKTSDIAGDGTTTATVLAQAIYREGVKNVAAGSNPMALKRGIDKAVTAVCGYNDAEGNRIPGALDKFSKPVTGEMIAQVGTISANNDETIGKIIAEAMKKVGKDGVITVEESKTMETQLEVVEGMQFDRGYLSPYFVTDPERMEAVLENPYILIHEKKVSSMKDLLPLLEQIAKGGRPLVIIAEDVEGEALATLVVNKLRGTLNVAAVKAPGFGDRRKAMLQDIAILTGGKAITEDLGIKLENVHMDDLGSAKKVTIDKDNTTIVEGKGKSSDIEGRVKEIRSQVEKTTSDYDREKLQERLAKLVGGVAVIKVGAATETEMKEKKARVEDAMHATRAAVEEGIVPGGGVALIRCVEAVDALKLTGDEGIGANIIKRALEEPLRQIVGNAGEEGAIVVGKIRDHKDPHYGYNAQTSEYVDLVKAGVIDPTKVTRTALQNAGSIAGLMLTTEALISEIPEEKKSEPAGGHGGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.