PharMolix/UniProtQA huggingface dataset:
Protein: UTP25_ASPOR
Sequence: MAPPRNRAPKGRGARARAPIKRRNGFTTSRVDEIESEEPSGGEEGQFEDNLGDEMDYDGPMDDASSDSDEDVEDDKSARPYNELLQLLNTTADSKAPARKKRKTEHKDDKRAVAQNDIVVAANEEELLEDDDLQQQEPSDEEDEDNLDEVDADGQADSDNEDDNDPFEAHFARKEDELSKQIKAVGDNKWKTVKKELSEDLRLARAAPDTGSDLSCLPALKSIANLKLKRKLKTPALERLSQISGHAQQLAPYIFDYQDVLYGARKSSSSTQLRDILAVHAVNHVLKTRDRVLKNNARVAKEQDADLDLRDQGFTRPKVLFLLPTKQACVRVVESITQLFQPEQQENKKRFMDTFSATDDKSWESKPDDFQELFGGNDDDMFRLGLKFTRKTVKFFAQFYASDMILASPLGLRTIMDQADAKKRDHDFLSSIEVVIVDQADALLMQNWDHVDYIFKHLNLQPREAHGCDFSRVRTWYLDNNARYVRQMIMLASFITPEINSVFSTHMLNVSGKIKMTPVYAGAISETPLPVSVKQTFSRFDSLSPAKDPDARFKHFTTTVLSSLVRNVTSGRGNNSGGILIVIPSYLDFVRVRNYFATSAQTMNVSFGAISEYSDTRDIMRARTHFMNGRHSVLLYTERFHHFRRYQIRGVKRVIMYGVPENPLFWGEIVGFLGMDPAAIDEAAEGGVRALFSKWDALKLERIVGTKRVGNMLREKGGDTFTFV
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYA_ACTSZ
Sequence: MKTTAEIRQSFLDFFHSKGHQVVESSSLVPENDPTLLFTNAGMNQFKDVFLGMDKRPYSRATTAQRCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFKYDAINFAWEFLTSPKWLALPKEKLYVTVYETDDEAYDIWNKEVGVPQEHIIRIGDNKGAPYASDNFWAMGDTGPCGPCTEIFYDHGDHIWGGLPGTPEEDGDRYIEIWNIVFMQFNRLADGTMEKLPKPSVDTGMGLERMTAVLQHVNSNYEIDIFQTLIKKVAEIVGTTDLGNKSLRVIADHIRSCAYLIADGVIPSNEGRGYVLRRIIRRAVRHGHLLGAKETFFYKLVPTLIEVMAEAGKQVKEKQANVEKLLRLEEEQFARTLERGLILLDAELANVKNGVLSGEVAFKLYDTYGFPLDLTADVCRERNIAVDENGFDKEMEAQRLRAQSASNFGMDYTSIIRVDGETKFEGYTNVESLAKVTALFRDGKAVESVSAGQSAVVILENTPFYAEMGGQIGDSGMLTANGLHFDVKDTQKYGQVFGHIGELTQGTLSVGQIVNAQVDAQRRQYTKLNHSATHLLHAALRQVLGEHVAQKGSLVSDVGLRFDFVQPEAVTKEQIMEIERLVNFHIRANHPVLTEEMGVAEAKSKGAIALFGEKYGETVRVVTMSPFSIELCGGLHVERTGEIGLLKIISEGAVAAGIRRVEAVTGEEAINWLFNQQTILAQSADLLKSDIPSLPEKIIQLQDKVKKTEKELQQLKEKAAMQAGSDLAKSAVKINGVSVVTHQLDGADAKVLRVMVDDLKNQLGSAVIALGSASGGKVNLIAGVTADLTAKVKAGELVNVMAQQVGGKGGGRPDMAMAGGSQPENLSAALIVASDWLKTMI
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_STRGG
Sequence: MKTIDELLAEGVAGKRVFVRADLNVPLDGTTITDDGRIRAVVPTIAKLAEAGARVVVASHLGRPKGAPDPAFSLAPAATRLGELLGAEVAFAADTVGESARAAVAGLADGRVAVVENLRFNAGETSKDDAERGAFADQLAQLADVYVGDGFGAVHRKHASVFDLPARLPHYAGYLIATEVGVLKKLTTDVHRPYAVVLGGAKVSDKLGVIDHLLERADRILIGGGMAYTFLKAKGYEVGSSLLQEDQIPAVREYLRRAEEKGVEFVLPVDVVVAPSFPDLKTKAPAHPTTVAADAMPAGQMGLDNGPETNKLYASKLADAATVFWNGPMGVFEHPDFADGTRAVAQALVDSSAFSVVGGGDSAAAVRILGFDENAFGHISTGGGASLEYLEGKTLPGLAALED
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS9_PASMU
Sequence: MQTTNLSYILGLDLGIASVGWAVVEINENEDPIGLIDVGVRIFERAEVPKTGESLALSRRLARSTRRLIRRRAHRLLLAKRFLKREGILSTIDLEKGLPNQAWELRVAGLERRLSAIEWGAVLLHLIKHRGYLSKRKNESQTNNKELGALLSGVAQNHQLLQSDDYRTPAELALKKFAKEEGHIRNQRGAYTHTFNRLDLLAELNLLFAQQHQFGNPHCKEHIQQYMTELLMWQKPALSGEAILKMLGKCTHEKNEFKAAKHTYSAERFVWLTKLNNLRILEDGAERALNEEERQLLINHPYEKSKLTYAQVRKLLGLSEQAIFKHLRYSKENAESATFMELKAWHAIRKALENQGLKDTWQDLAKKPDLLDEIGTAFSLYKTDEDIQQYLTNKVPNSVINALLVSLNFDKFIELSLKSLRKILPLMEQGKRYDQACREIYGHHYGEANQKTSQLLPAIPAQEIRNPVVLRTLSQARKVINAIIRQYGSPARVHIETGRELGKSFKERREIQKQQEDNRTKRESAVQKFKELFSDFSSEPKSKDILKFRLYEQQHGKCLYSGKEINIHRLNEKGYVEIDHALPFSRTWDDSFNNKVLVLASENQNKGNQTPYEWLQGKINSERWKNFVALVLGSQCSAAKKQRLLTQVIDDNKFIDRNLNDTRYIARFLSNYIQENLLLVGKNKKNVFTPNGQITALLRSRWGLIKARENNNRHHALDAIVVACATPSMQQKITRFIRFKEVHPYKIENRYEMVDQESGEIISPHFPEPWAYFRQEVNIRVFDNHPDTVLKEMLPDRPQANHQFVQPLFVSRAPTRKMSGQGHMETIKSAKRLAEGISVLRIPLTQLKPNLLENMVNKEREPALYAGLKARLAEFNQDPAKAFATPFYKQGGQQVKAIRVEQVQKSGVLVRENNGVADNASIVRTDVFIKNNKFFLVPIYTWQVAKGILPNKAIVAHKNEDEWEEMDEGAKFKFSLFPNDLVELKTKKEYFFGYYIGLDRATGNISLKEHDGEISKGKDGVYRVGVKLALSFEKYQVDELGKNRQICRPQQRQPVR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein.  The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA.  Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA).  Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs.  PAM recognition is also required for catalytic activity (By similarity).  Cuts target DNA in Cas9:gRNAs mixing experiments with C. jejuni strain NCTC 11168 and N. meningitidis strain Z2491.
What are the official names of this protein?
CRISPR-associated endonuclease Cas9.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas9 family. Subtype II-C subfamily.
Protein: ILVC_POLNS
Sequence: MKVFYDKDADLSLIKGKKVTIIGYGSQGHAHALNLKDSGVNVTVGLRKDGASWSKAANAGLTVKEVDEAVKDADVVMMLLPDEQIADVYNKEVHGNIKQGAALAFAHGFNVHYGQVQSRADLDVIMIAPKAPGHKVRGTYAQGGGVPHLIAVYQDKSGSARDVALSYATANGGGRAGIIETNFREETETDLFGEQAVLCGGAVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEDTKNAMRQCLKDIQTGEYAKSFILENKAGAPTLISRRRLNAEHDIEVVGAKLRAMMPWIAKNKLVDETKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SSRP_POLSJ
Sequence: MRIADNKKAIFNYHIEERFEAGMVLEGWEVKSVREGKVQLTDGYVVIRGGELFIIGCQINPLGTASTHVRPDSVRTKKLLMHKDEIRRLVGKVEQKGFTLVPLNMHWKAGKVKCEIGLAKGKGEHDKRDTIKDREGKREVERAMKSRSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LPXA_CHLP8
Sequence: MSSIHPTAVIGSGATIGEDVQIGPYTVIDDDVVIGDRTVIAPHVYIADGARIGSECRIHSGAVLSTAPQDLKYAGEKTELYVGDRTVIRECVTLNRGTKASGKTVVGSDNLLMAYVHAGHDCVIGNHVVIANSVQFGGHCEVGDYVVVGGLAGIHQFVRIGRYAMVGGISRGALDVPPFVMAGGHNSFRYEGLNVIGLKRRGFTSEQISTIRDVYRVIFQSGLLLSNALEAVRRDFEQTPEVKEILGFFASGAHGRKFLKPFNS
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CAMC5
Sequence: MKKEIHPEYIDCTVTCACGNTFKTKSNKSEIKIDICDKCHPFFTGSEKIVDSAGRVEKFKKKYALN
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: BSUHB_AQUAE
Sequence: MENLKKYLEVAKIAALAGGQVLKENFGKVKKENIEEKGEKDFVSYVDKTSEERIKEVILKFFPDHEVVGEEMGAEGSGSEYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVYLPYFDKLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGFPSRSRRDISIYLNIFKDVFYEVGSMRRPGAAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYTLVGEPFGVSDIIAGNKALHDFILQVAKKYMEVAV
What is the function of this protein?
Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1-phosphate (I-1-P).
What are the official names of this protein?
Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, FBPase/IMPase, Inositol-1-phosphatase, I-1-Pase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.
Protein: UFM1_DROPS
Sequence: MSKVTFKITLTSDPKLPFKVLSVPEGTPFTAVLKFASEEFKVPAETSAIITDDGIGISPQQTAGNVFLKHGSELRLIPRDRVGH
What is the function of this protein?
Ubiquitin-like modifier protein which binds to a number of as yet unidentified target proteins.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
Protein: GATA_CUTAK
Sequence: MNELLTLTAAELGERIAARQISSEEVTQAHLDRISEVDGDIHAFLLVDHAGALDAARRIDARIADGEHLGPLAGVPLAVKDLFCTKGIATTASSQMLEGWIPPYDSTIVTRCKDAGMVILGKTNLDEFAMGSSTETSAFGPTHNPWDLERVPGGSGGGSAASLASFQAPLALGTDTGGSIRQPGAVTGTVGIKPTYGSTSRYGVIAMASSLDTPGPCARTVLDAALLHQAIAGHDAMDQTTINQPTPAVVEAARQTDVSGVRIGVVTELSGQVYDPQVEARFHEAVEMLIEAGAEVVEVSCPNFDLALPAYYLIQPAEVSSNLARYDAMRYGLRVNDDGEHSAEQVMRATRGAGLGAEAKRRIILGTYALSAGYYDAYYGSAQKVRTLIQRDFEKAWQMCDVLVSPATPTTAFRLGERTADPMAMYRSDLCTVPANMAGSPAGSFPIGLSETDGMPVGMQVMAPIMADDRIYRVGAALERLLHEKWGAPLLAKAPEVRGER
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: KCY_DESA1
Sequence: MVKIVFSGPPGSGKTTQAKRVAEYYGLKYFSAGSLFREYARRKGVSLEELSRIALEDPSIDLEIDRMTLETVRDSDDIVIDGHLAAWIVSDIVDLKIYVTAPLTLRILRVAGRDNTPLGKALAETLIREYSQRRRFMEYYGIDIYDTSIFDLTINTKLIGVEEAFNIIKSIIDKILKEKHGSMSE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CRAPA
Sequence: MTIMRKSHPLMKIVNHAFIDLPTPPNISGWWNFGSLLGLCLILQILTGLFLAMHYTSDTLTAFSSVMHTCRDVNYGWLIRHMHANGASLFFICLYIHIGRGIYYGSYLYKETWNIGILLLFLTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGQDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPLGIPSDSGKVPFHPYYTTKDFLGVILLLTLFMTLVMFFPDKLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVCALVFSILVLALLPYLHTSKQRSLSFRPLSQTLFWTLVSDLVILTWIGGQPVESPYIIIGQVASILYFSIILVFMPIAGLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BRO1_CRYNB
Sequence: MSVQSPLIAVPRKTTTDVDWATPIRHVIAASYGEDPNSYAEECAVLQRCRQDAVRGAGNDQTARDLLYKYFGQLELLELRFAEIKVSFPWNDAFTDKLTTQTSLAFEKASIIHLISSILSSLAQSASRSDPEGLKRAYYNPRATAGMLTYINENFLHAPSTDLSREVVHLLIGIMMAQAAEIFTEKLVEEKKSASLVARSANQTASMYTSVVDEMKEFQGKGVFDRNWLYVLQIKAKLFGSLTQYYKATSDSAAGKHGTALVRLKIANSLIQDAQKQASSFIYTFVAASTPSLPHDAANALNEIVKAHATVCGEAKEQAVKDNDLIYHEVLPSEASLPAIEKLPPAAPITIQDVYGNQEVTKLIGPDIFLRLVPLAVHESASVYSEEKAKLVRAEVDKVELAEGEIQAGLDHLNLPEEIDRWRQFLEGDTNDDVPLSQQLKSLVDSVGDVRQVENDLGRLDGERGACERELRELNGALDAESRECERMRAKYTPNFTQSPSGPQTANLRSNLSANLSALSSASTSDAHLQSLWQSIQPSISLLSSGPSNLERAARDITEGNSQKIDKTVSLLDLDDEEVDRKALGQEEKDALRKAVDDGREKLDRLKKIRAERDEVLRDLKEKIQTDDVSNLLLLNRRSQNVEPQLFASELEKFRPYQTRLAAAVSASRSILQELDMLVAQVHKGTGFREILRKEKDRQRIIRDWEKRLIEAGESYAEIRAGLGKGLSYYDSLRRVIEDLRMEVQRFTNSREQERRNMVSDIETRQRLGGTSPSTGGVVANRGLEERLAALKMEAPPQPPRLGTTSTPNLPPPPGRGSSNVTSSYLPPPPPPKPQSNPYDFSTLAGFGSFATPSVSSPQHVYPSQPQQAYNQQSYIPPQQNPYYPPPPSRPTYASPPFAPQQPPMQSGHSPYAPPPGHAPQPQQPQYPSSQNQQQRQGYEYPGYGQQGGYGGGYGQY
What is the function of this protein?
Involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.
What are the official names of this protein?
Vacuolar protein-sorting protein BRO1, BRO domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the BRO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: PA2B1_DABRR
Sequence: MRTLWIVAMCLIGVEGNLFQFARMIDAKQEAFSFFKYISYGCYCGWGGQGTPKDASDRCCFVHDCCYARVKGCNPKLVEYSYSYRTGKIVCETYNRCKRAVCECDRVAAICLGQNVNTYNKGYMFLSSYYCRQKSEQC
What is the function of this protein?
Exhibits high hydrolytic activities and shows strong preference for the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Drk-b1, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_BORPA
Sequence: MADLFALTEEALAGMDIELVDVERAAMGLLRVTIDRVDGVRIEDCEQVSRQLSHVYEVENIDYKRLEVGSPGVDRPLRNEAEFRRFAGERIEIKLREALDGRKVFSGTLRAPEADGASGQDDTAGAGKAVFGLEFEAKKNDIQVLSFTLDDIERAKLDPVLDFKGKKR
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDL_YERPA
Sequence: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: BI1_PAROL
Sequence: MNVFDRNINFDSLFKFSQISHSTQVHLKNVYSSLAVCMFVAAAGSYVHVVTRLFQGGMLSVLGSLGMMFWLAMTPHNSETEKKRLAILAGFAFLTGVGLCPTLDFVIAINPSIIVTAFLGTSVIFVCFTLSALYAKRRSYLFLGGTLMSGLSILFLMSMMNMFFGSVMLFKAHMYLGLLIMCGFVLXDTQLIIEKAENGDKDYVWHSVDLFLDFITIFRKLMVILALNDKDKKKEKK
What is the function of this protein?
Suppressor of apoptosis.  Modulates unfolded protein response signaling.  Modulate ER calcium homeostasis by acting as a calcium-leak channel (By similarity).
What are the official names of this protein?
Probable Bax inhibitor 1, BI-1, Testis-enhanced gene transcript protein homolog, Transmembrane BAX inhibitor motif-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RUBR1_DESDA
Sequence: MQKYVCNVCGYEYDPAEHDNVPFDQLPDDWCCPVCGVSKDQFSPA
What is the function of this protein?
Electron acceptor for cytoplasmic lactate dehydrogenase.
What are the official names of this protein?
Rubredoxin-1, Rd-1.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EQXG_GIBF5
Sequence: MSTTPQMSQSGFQDDQLEAGAREDVGTEAQEKPLSTTGTMVDEPQPNPNVVDWDGPDDPQHPLNWSKAQKNLHVGIVSLSTLAANLAATMFAPGAAELSDEFNITSATVTAMTVSLYVLGFALGPLLLAPLSELYGRLIIYHFCNMVYMAFTIGCAFSTNVAMFLVFRIIAGCAASGPMSIGGGTVADLFVQEQRGKAMALFAVGPLLGPVIGPIIGGFVSENVGWRWTFRILLILSGILATVTFALMKETNYTVILQKKALRMRKETGNEKLVAKSSRDETAGQMLARAIVRPLKLLIFSPIVLLVSLYTGILFGLIFLLFTTFPSVFQDVDKLLGSKKGEENAAPRPEDRLLLMKWLGPITPLGLFIYGWTAENRVHWIVPIIGTFIVGFGSLFVVIPGQIYLVDAFGAEAAASAMAANLLVRSPFGAFLDLTAEPLYSKLGLGWGNSVLGFITLAFTPVPWIFYTYGERLRTHFQVDL
What is the function of this protein?
Efflux pump required for efficient secretion of trichosetin or other secondary metabolies produced by the trichosetin gene cluster (PubMed:28379186).  Plays a crucial role in detoxification of the toxic trichosetin in Gibberella fujikuroi cells (PubMed:28379186).
What are the official names of this protein?
Trichosetin biosynthesis cluster MFS transporter, MFS-T.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIPK1_RAT
Sequence: MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQASSSHQVANFNIPAYDQGLLLQAPAVEHIVVTAADSSGSAATATFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRVTPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPSTSTNLTMSFSNQLSTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPPSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPLVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVQQAWPGGTQQILLPSAWQQLPGVALHNSVQPTAVIPEAMGSSQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSRKNKQSAPVSSTSSLEVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKFKPSSSSLKARSNVISYVTVNDSPDSDSSLSSPYPTDTLSALRGNSGTLLEGPGRTAADGIGTRTIIVPPLKTQLGDCTGATQASGLLSSSKTKPVASVSGQSSGCCITPTGYRAQRGGASAVQPLNLSQNQQSSSASTSQERSSNPAPRRQQAFVAPLSQAPYAFQHGSPLHSTGHPHLAPAPAHLPSQPHLYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis.  Plays a role as a corepressor for homeodomain transcription factors.  Phosphorylates DAXX and MYB.  Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm.  Inactivates MYB transcription factor activity by phosphorylation.  Prevents MAP3K5-JNK activation in the absence of TNF.  TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis.  May be involved in anti-oxidative stress responses.  Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis.  Promotes angiogenesis and to be involved in erythroid differentiation.  May be involved in malignant squamous cell tumor formation (By similarity).  Phosphorylates PAGE4 at 'Thr-51' which is critical for the ability of PAGE4 to potentiate the transcriptional activator activity of JUN (By similarity).
What are the official names of this protein?
Homeodomain-interacting protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus speckle. Note=Predominantly nuclear. Translocates from nucleus to cytoplasm in response to stress stimuli via SENP1-mediated desumoylation (By similarity).
Protein: SYC_STAHJ
Sequence: MITLYNTLTRQKETFEPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYKGYEVIYVSNFTDVDDKLINRSKELNESVPDIADRYIKAFYEDVGALNVKKATSNPRVMNHMDEIIDFIKELVDEGYAYESDGDVYFRTRKFEGYGKLSHQSLDDLKVGARIEAGEQKEDALDFTLWKKAKPGEISWESPFGEGRPGWHIECSVMAFHELGKTIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVNAAKSGLERIRNSYQLIEERETIATDIVDQSKYIEQIDAIIEQFETVMDDDFNTANAVTAWYDLSKLANKYVLENNTSTQVISRFKEVYQIFSDVLGVPLKGNKSDMLLDEDIEKLIEERNEARKNKDFARADEIRDMLKEQNIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBPA_NEIMB
Sequence: MQQQHLFRFNILCLSLMTALPAYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDSSNYAYFIVKEECKNGSYETCKANPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANKKQAGSLPGNGKYAGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGIGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYYQHANRAYSSNTPPQNNGKKISPNGSETSPYWVTIGRGNVVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMKF
What is the function of this protein?
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host.  Acts as a TF receptor and is required for TF utilization.  Binds both apo- and holo-TF, via the TF C-terminus.
What are the official names of this protein?
Transferrin-binding protein A, TbpA, Transferrin-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.