PharMolix/UniProtQA huggingface dataset:
Protein: RNZ_PYRNV
Sequence: MPLLKLVFLGTGGAVPRSDRTLPAIYLEDWLGHRFLLDAGEGAQYRLLQIGVSPASLTAVAITHQHEDHTLGLPGLVITSRFLGGRTAVLAPRSMHKALEALGVEVMDSYGGDRLRVSCVEVCHTVDACGWLFQWDVGYKLDLSKAAGLPRWALTSLIRGSPVEVGGRLIKPEDVAEPGHKRLRRLLYTGDTAPCPEMWRKVGEVDVLIHEATFADDVEPQKAHEEGHSTVADAVEAAKALNAGVLILTHVSSRYPDKRRHRELAASVKPPPHVYVPEDFDTVLVRL
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: SECB_PECCP
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQEWQPEVKLDLDTASSQLADDIYEVVLRVTVTASLGEETAFLCEVQQGGIFTVGGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQTEGEGAAQHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP2_NATPD
Sequence: MKHLPKHLRPRWRYLAVGLESWPDADIDRRAFQRELWFAAQNLIGDAGSAALDGSVLHFRFEDGDGEAVIRARRGEVDALRAVLATLSTVDGHPLGVVVRGVSGTVRACEEKYIRGPQEGTEERTVAFAGADRPAVVRNDRVTVELSGGPVGATALDIRDN
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_ENT38
Sequence: MKTAYIVKQRQISFVKSHFSRQLEEKLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKTLPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLTAIHSVYVDQWDWERVMGDGERHVGTLKSTVEAIYAGIKATETAVSKEFGLTPFLPDTIHFIHSQDLLSRFPDLDAKGRERAIAKELGAVFLIGIGGKLSDGKRHDVRAPDYDDWSTSGESERAGLNGDILVWNPILEDAFELSSMGIRVDADALKRQLAVTGDEDRLKLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLSHIGQVQCGVWPQQVRASVDSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_STAAS
Sequence: MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQLKTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKSLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFZ3_SCHPO
Sequence: MSQTTTETIIPLDSSVKDKLDPEYVNFYNKYVCSNLPIVKTHTYPVDFLRNNGNVMPGQSELLPVESTEDITIPRKHTKAPSGVPSRIFRPHGTAPEGGWPCFLWFHGGGWVLGNINTENSFATHMCEQAKCVVVNVDYRLAPEDPFPACIDDGWEALLYCYENADTLGINPNKIAVGGSSAGGNIAAVLSHKVAASPANFPPLVLQLLVVPVCDNTANAKTHKSWELFENTPQLPAAKMMWYRRHYLPNEKDWSNPEASPFFYPDSSFKNVCPALICAAGCDVLSSEAIAYNEKLTKAGVESTIKIYEGCPHPVMAMDAVLEKGRILNKDATNALLAAFA
What are the official names of this protein?
AB hydrolase superfamily protein C1039.03.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YO365_YEAST
Sequence: MLPIKVFSLSRIFVLLAIFRQIHAISINSSTFQVSNSFTLLNNASTLFPVPFDAYTKEYLRTSALLTCAKDSQFSASYFEAAFFPRNNTLFFNVEAQTIMSENITIKAELIAYGLNVYTKVFDLCGIQDNLLCPLKPGNIELMGSYYVEAAVASQIPSITYNIPDLDAYIVVTAYSTIDKEFTKPLACVQVMLSNGRTVQTEYLSWNLVILTISGIMFSVVYSLQGYTVTSTRLASYSISLLLYFQNLAILAMISVSFLPPIVAAWTQNFQWSMGIIRINFMQRLFDWYVVATSGSPTVVYRNKEVLSISVQKRSLNSKIISASSNLNGIESSQKNDLLYTSNLRNSNDYLSKILVLRGIKRVSYKAGIEISNFFLTGFSFFIIFICMIILAFIIFKTFLKVLQKFKVKTIRYLHFHTHWSALLQGTLYRAVFIIYSEISLLALWEFTQTDSAATLVEAIVVFILITVLLSSASVRIWRKMIKSKKIFGQPSYLLFSSSKFLNKFGFLSSQFKSTKVWWLMATSAHMLIRSILVGSLQAHGKSQSIGIFLNEAIYLILLCWMQPYMDKTTNFFNISIHSLNLVNAFFFLFFSNLFQQPIAVSSFMGLIFFFLNAAFSLYLFIFILICFTMAIYYKHPDTRYKPIDDQRRSFLKGEMDDDAVYESVPELHEMKKAVLECNGIQKPQINKIDLCKQNSNCEYLYM
What are the official names of this protein?
Uncharacterized membrane protein YOR365C.
What is the protein family that this protein belongs to?
Belongs to the transient receptor potential (TRP) ion channel family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FLIE_ECODH
Sequence: MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: LGT_PROM5
Sequence: MLTHQAFIQSPGDTFLNLGFLTIRWYGLLISLSVLIGIFISKKLAKSRNINPQYISDILPSLIISSIIGARFYYVIFEWKQYSGNNFFTSFNLFDNVIQIPSFLAIWEGGIAIHGGLIGGFLSILFFCKSKNIHLKTFMDILIPSIILGQSIGRWGNFFNNEAFGIPTELPWKLFIPLQNRPIEFINYQFFHPTFIYESLWNFLIFILLISIFYKQNTNSSLRPGFISCLYLIGYSFGRFWIEGLRIDPLCLGGLPPFCDGGLRMAQFISIVLFSSGLIGIFFLRLKTYNKKTRKNG
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_RICB8
Sequence: MATKKAGGSSRNGRDSAGRRLGVKKADGQYVIPGNIIVRQRGTKIHPGVNVGIGKDHTIFALTSGRVEFLTKRDHKIVNVTEIASA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LEU3_PSE14
Sequence: MSKQILILPGDGIGPEIMTEAVKVLELANEKYQLGFELTHDVIGGAAIDKHGVPLADETLDRARAADAVLLGAVGGPKWDTIERDIRPERGLLKIRSQLGLFGNLRPAILYPQLADASSLKPEIVAGLDILIVRELTGGIYFGAPRGTRVLDNGERQAYDTLPYSESEIRRIAKVGFDMAMVRGKKLCSVDKANVLASSQLWREIVEQVAKDYPEVELSHMYVDNAAMQLVRAPKQFDVIVTDNLFGDILSDQASMLTGSIGMLPSASLDTANKGMYEPCHGSAPDIAGKGIANPLATILSVSMMLRYSFNLTDAADAIEKAVSVVLDQGIRTGDIWSEGKVKVGTQEMGDAVVAALRNL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFG_CERS1
Sequence: MTDDTAAPPPRGPARDWKSSPLVSGLLLGLFSLVSALMLALASDATRGPIAARSAEDLLASLAQVLPAALHDNDPTADIRTLADADEGAVRVYVATRGGAVTAVTFELTGYGYGGAIRVLMAVAADGTILGARVLSHTETPGLGDKIEIGKDDWIEGFAGRSLTDPGPAGWKVRRDGGVFDQFSGATITPRAVVGTIHRGLTLFDRHRAELLAPLPLRS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Single-pass membrane protein.
Protein: GLUC_TRASC
Sequence: HSQGTFTSDYSKYLDTRRAQDFVQWLMST
What is the function of this protein?
Glucagon plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YFCN_ECO27
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: RUVC_PSYA2
Sequence: MAIIIGIDPGSRMTGYGILQQTGDKLTYIDSGTIRTDTKEMPERLKRIFNGLTRITQHHLKYADEPIYTAIEQVFMAENPDSALKLGQARGAAIAAMVALDLEVSEYTARQIKQAVCGYGAAAKEQVQDMVCRILTLDFVPQQDAADGLACAICHAHSSHSMNKLILNSAMRGRGASKKKGRWRLTEEDLGNLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GSA1_LISMF
Sequence: MQNYSKSEKAFKEAKKVLPGGVNSPVRAFNSVDASPVFMDHGKGAYITDVDGNEYIDYVLSWGPLILGHADPAVVNAITKAALKGTSFGTPTEIETELAKLVIERVPSIEIVRMVSSGTEATMSAIRLARGYTKREKILKFEGSYHGHGDSLLIKAGSGVATLGLPDSPGVTKGLAADTITVPYNDIEGAELAFQKYGEEIAAVIVEPVAGNMGVVPPIDGFLEGLRELTTKFGSLLIFDEVMTGFRVDYYSAQGYYVVTPDLTCLGKVIGGGLPVGAYGGKKEIMEQIAPAGSIYQAGTLSGNPLAMNAGFETVRQLTPQHYDVFRTLIKRMEEGLTEISARRQVPLSINKAGSMFGFFFTDQKVINFDTAKTSNLEFFRNYYREMLGQGIFLPPSQFEGVFISTMHTEKEIDKTLEAFDTTCKILRG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_ECO5E
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLAWLINDIPLPGTTGVERVLFSALGVSNHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALVIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPO4_PSEA7
Sequence: MRKIIHIDCDCFYAALEMRDDPSLRGKALAVGGSPDKRGVVATCSYEARAYGVRSAMAMRTALKLCPDLLVVRPRFDVYRAVSKQIHAIFRDYTELIEPLSLDEAYLDVSASPHFAGSATRIAQDIRRRVAEELRITVSAGVAPNKFLAKIASDWRKPDGLFVITPEQVDGFVAELPVAKLHGVGKVTAERLARMGIRTCADLRQGSKLSLVREFGSFGERLWSLAHGVDERPVEVDSRRQSVSVECTFDRDLPDLAACLEELPALLEELDGRLLRLDGSYRPDKPFVKLKFHDFTQTTLEQAGAGRDLDSYRQMLGQAFARGSRPVRLIGVGVRLLDLQGAHEQLRLF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLUR2_HUMAN
Sequence: MQLGTGLLLAAVLSLQLAAAEAIWCHQCTGFGGCSHGSRCLRDSTHCVTTATRVLSNTEDLPLVTKMCHIGCPDIPSLGLGPYVSIACCQTSLCNHD
What is the function of this protein?
Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors.  May regulate keratinocytes proliferation, differentiation and apoptosis.  In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs.  Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner.
What are the official names of this protein?
Secreted Ly-6/uPAR domain-containing protein 2, Secreted LY6/PLAUR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2, SLURP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_TERTT
Sequence: MYAVIAAGGKQHRVEEGEVLRLEKIEVATGETVDFDQVLLVGSGADVKIGTPVVEGAKVTAEVVSHGRADKVTIIKFKRRKHHMKRQGHRQWYTEVKITGIQG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ELP4_DROME
Sequence: MTSFRKRTVQKPIRGTRTSPHTAQVITSSGNPYLDVVIGGGLPMGSICLIEEDRFMTHAKVLAKYFLAEGVISKQEIFLGSLDDIPAEMLRRLPRPLTDQESMEQSEVQALGDAGAENGLRIAWRYNDLPLVNSEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSKSSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSPLQVFHNPRYKGLLNDIQQLLRNESFVAGTKNNLCRVCLTSLGSPLWYDEHFGEDLIKFLTLLMASVRNCNSVCLITMPMHLIAKYDASLVPKIRQLVDYAIELESFAGSERETHPAFKEYSGLLHLHKMSAINTLAVHMPETPDLAFKLRRKKFIIEKFHLPPELQESSAKPDNCISGLLSNSNATASLDF
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).  The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
What are the official names of this protein?
Elongator complex protein 4, ELP4.
What is the protein family that this protein belongs to?
Belongs to the ELP4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NADA_SINFN
Sequence: MTRLDLRAGAAPAPAFVSAAARYGVIERPDLAFTPAIARETAHLYEKVKDFIPAFEWAAYAPYVHAINRLKKERNAVILAHNYQTPDIFHCVADIVGDSLQLARDATKVDAEIIVQCGVHFMAETSKLLNPEKTVLIPDAKAGCSLSESITGADVRLLKERYPGVPVVTYVNTSADVKAETDICCTSSNVLAVVESLESDTVLCIPDEYLAMNVARQTNKKILTWKGHCEVHERFTAAELLAYKEANPGIEIIGHPECHPDVIEVCDFSGSTSGMINYVKDKRPQRVLLVTECSMASNIQAEVQGVDFVKPCNLCPHMKRITLPKILDSLLNMTEEVLVDPAIADRARLAVERMVNLKQ
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC_YERPY
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGATARQIGEWQGQPVWLIRQMMPSGMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRFCGYCGHEMHASRTEWASLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMADYDSGELCHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREHSDLSQ
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: TBG2_MAIZE
Sequence: MPREIITIQVGQCGNQIGMEFWKQLCLEHGIGKDGLLEDFATQGGDRKDVFFYQADDQHFIPRSLLIDLEPRVINGIQNSEYRNLYNHENIFVAEHGGGAGNNWASGYHQGEQVVDDIMDMVDREADGSDSLEGFVLCHSIAGGTGSGMGSYLLETLNDRYSKKLVQTYSVFPNQMETSDVVVQPYNSLLTLKRLTLNADCVVVLDNTALNRIAVERLHLSNPTFAQTNSLVSTVMSASTTTLRYPGYMNNDLVGLLASLIPTPRCHFLMTGYTPLTVERQVNMIRKTTVLDVMRRLLQTKNVMVSSYARTKEASQAKYISILNIIQGEVDPTQVHESLQRIRERKLVNFIDWAPASIQVALSRKSPYVQTTHRVSGLMLANHTSIRHLFGKCLGQYEKLRKKQAFLDNYRKFPMFADNDLSEFDESREIIESLVDEYKACESPDYIKWGMEDPGEANVAADLDSKLVV
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-2 chain, Gamma-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center.
Protein: FABH_BORPE
Sequence: MEKAMKYAKIAGSGGYLPERVVTNDDLAAELATRQISTSDEWIVERTGIRQRHLAERGVTTSQLATEAARRAMDDAGVQADEIDMIIVATSTPDYVFPSTACLVQANLGAKGGAAFDVQAVCSGFVYAMTTADNFIRAGRARCALVIGAEVFSRILDWNDRGTCVLFGDGAGAVVLKAADEPGILAAHLHADGSQTKILCAAGNVAYGDVTGDPFLRMDGQAVFKQAVTVLDRSARDVCAEAGVEVDDIDWLIPHQANVRILNFLARKLRVPTERVVITMDQHANTSAASVPLALDVARRDGRVKPGQLVLMQGVGGGFTWGSVLARM
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_GLACH
Sequence: VDFNVPLKEGVVKDPTRIAGSIPSIKKILETNPRGLVLMSHLGRPDGQRVEKHSLKPVLPKLEELLGTKVTFLNDCVGKDVEEAVKSSRNGEIILLENLRFHIEEEGKAVDAAGNKVKADPKAVKEFRKSLTNLGDLFFNDAFGTAHRAHSSMVGVDHKIRVAGYLLKKELEYFSKALESPTLPFCVVLGGAKVKDKIQLINSMLDNVNEMIIGGGMAFTFLKRLHNLEIGNSLFDEEGYKIVDELLEKAKKKNVKIHLPVDFLCGDSLEANANTAIHDLQSGIPKGWIGLDAGPKTIALNAEVIARANTIVWNGPQGRFEVDKFRNGSSDLLKKVIERTKTGATSIIGGGDTVNLVQQEKASNKVSHVSTGGGAS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
Protein: RL29_PSEA6
Sequence: MKATELKDKSVEELNTELLNLLREQFNLRMQASTGQLEKTDQIRKVRRSIARVKTILTQKAAA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: AACUK_ASPA1
Sequence: MAKPTAPCFEDVLGCQAALYEWAESYDTKDWDRLAQCIAPTLRIDYRAFLNKLWEEMPAPEFLLMASDLKFLGNRRLKTQHFVGGASKWLQTSEDEITGQHQMRVAHQKYADDALSEVALKGHAHGHATIWYRRVEGQWRFAGIEPGIRWSEYDHDRIFFEGEEKLGEPQSDECAC
What is the function of this protein?
Scytalone dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
Scytalone dehydratase-like protein AacuK, Secalonic acid biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: Y500_AERPE
Sequence: MRVEIVAADSLGVRSIATFVEACGYSIGVDLGASIAPRRFSLPPHPRELRRLEQALDRARRRLEESNIAIITHYHYDHYLRDEPELYAGRLLLAKDINRSINRSQRFRGYRFLVKSGLVERGRVEYADSRVFRLEGGLTIEFSKPVWHGEEGTKLGKVLMVRITCEGVSIVFASDVQGPGNNEALEELLKWSKPRPLVLIISGPPLYLGGYRVGMSSVELGIRNLEVLAERLRPKRLVVDHHLVRDPRFPEVLERLRGRAAGAGVEVLTAAEYMGLRPEPLETMRRELWKGEEG
What are the official names of this protein?
UPF0282 protein APE_0500.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.