PharMolix/UniProtQA huggingface dataset:
Protein: KDPA_PSEPK
Sequence: MHSYDFALLLAFFVIVLLPAPWLGRFYYKVMEGQRTWLTPVLGPVEQGCYRLAGVNASQEQNWRQYTLALLAFNLVGFLLLFAVLLLQGYLPLNPQNLPGQEWSLAFNTAVSFVTNTNWQAYSGEASVSYLSQMLGLTVQNFVSPATGLAVLVVLCRGIARRSATTLGNFWVDMTRATLYGLLPLCLLLALLLVWQGVPQTFADYAHALTLQGADQTIPLGPAASQIAIKQLGTNGGGFFGVNSAHPFENPTAWSNLFEVASIILIPVALVFTFGHYVKDLRQSRAILACMLALFLIGGSTALWSEHQPNPALESTQVQQTAPLEGKESRFGTTGSVLWAVTTTAASNGSVNAMHDSLNPLTGMVAMVNMMVGEVIFGGVGAGLYGMLLFVLIAVFLAGLMIGRTPEYLGKKLQAREVQLLVATLLVMPVGVLVLGAIAASLPGPAGAVTNPGAHGFSQLLYAYTSGSANNGSAFAGFGANTVYHNLMIGLAMLIGRFGYILPILALAGSLAAKKSAPLGQNSFPTHGPLFTGLLLVTILLVGGLTFLPTLALGPIAEHLSLGF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DED1_CANGA
Sequence: MTELAEQVSMPEGQQRRGGYVPPHIRNGGGRRGDSAPRGGFNNGGGRGGFFRNNGDRGGFGFGGRGGGFGGNRGGFGGNRGGFGGGMRGRWVDGKHVPGQRNERIELELFGAPEDPSFQSSGINFDNYDDIPVEASGEDVPEAITEFTSPPLDSLLLENIKLARFTKPTPVQKYSVPIVSKGRDLMACAQTGSGKTGGFLFPVLSESFLTGPAEKAANDGYSYQRKAFPTAVVMAPTRELATQIFDEAKKFCYRSWVKPCVVYGGAPIGNQMREMDHGCDLLVATPGRLNDLLERGKVSLSNVKYLVLDEADRMLDMGFEPQIRHIVEDCDMPPTGERQTLMFSATFPHDIQHLARDFLHDYIFLSVGRVGSTSENITQRILYVENRDKNSALLDLLAASNDNLTLIFVETKRMADQLTDFLIMQNFSATAIHGDRSQAERERALAAFRSGRANILVATAVAARGLDIPNVTHVINYDLPSDVDDYVHRIGRTGRAGNTGVATAFFNRDNNNIVKGLYEILEEANQEIPPFLEDCLREVSFSRSGSNRSTRGNRSSNTRDYRKHGGNGSFGQNSRNSSWGSARGGGFGGSTGGWGNDRAGGSAGGWGASNTKTSSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DED1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_CAUSK
Sequence: MTDVAEEAGWATAKTLAEALPYIQIYDRETVVIKYGGHAMGQEQVAKLFAADAVLLKLLGVHPVVVHGGGPQISRMLDKAGVKSTFVDGLRVTDEATMEVAEMVLSGAINKEIANWITLAGAEADVRGVGLSGKDARMITAEKVTRTRKDPGSNIEQVVDLGFVGEPTKIDPHIIQALLTSETDYIPVIAPIGVSTEGQTFNINADTVAGALAGALKAKRMLMLTDIAGVLDADGNLIRAMTVAEARALIESGVASGGMIPKLENAIHAVENGVEAVVILDGRRPHAMLVELFSEHGAGTLISK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_BUCAT
Sequence: MKIYLVGGAVRDSLLNLPVKDKDWVVVGGTEKILLERNFQQVGKDFPVFLHPETHEEYALARKERKSGKGYTGFDTDCNSDVTLEEDLIRRDLTINAIAQDEYGNYIDPFQGKKDIECGLIRHVSESFIEDPLRVLRVARFAATLVHLGFKIAEETMLLMCIIVKKQELSYLTSNRIWNETEKALKTLNPHVYFQVLYECNALHFFFPEMYFLYEKKNFLNRSFFKKFCNKNIILMGLAEISLLNKDIDVRFSYLCQFLSVNQIDRNYSKIFFDSYAASIIHSLCKRFKIPSYIRDIAVLNTGFYFFLNTIHYQSSKNIINLFSKVDAWRKPDRVKKLAFLSNFNFLRNFKSEFFCIKSGCFLEKCFSVVKNVSIKLILKKGFKGYEIKQEITRLRIKKLEFWRIKNIKHRFYL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: ALR_NEIG1
Sequence: MRPLNVQIRLGNLRHNYRILKEMHGGKLLAVVKADAYGHGAVRCAFALADLADGFAVATIDEGIRLRESGITHPIVLLEGVFEASEYEAVEQYSLWPAVGNQWQLEALLSRHWKKPVKVWLKMDSGMHRTGFFPHDYTSAYAALKQSEYVDSIVKFSHFSCADEPESGMTEIQMEAFDLGTKGLEGEESLANSAAILNIPEARRDWGRAGLALYGISPFGGSDDRLKPVMRLSTRIFGERVLQPHSPIGYGATFYTSKSTRVGLIACGYADGYPRRAPSNSPVAVDGKLTRVIGRISMDMMTIELDASQEGLGHEVELWGDTVNINTVAEAAGTIPYELMCNIKRAKFTYIE
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FENR2_CUPPJ
Sequence: MDLSIPNPVADTTKAADAGTAGGQPLEIDALIVGAGPVGLFQVFELGLLEIKAHVIDSLKVVGGQCVELYPDKPIYDIPAVPSCTGQELTDNLLKQIEPFGPTFHLGQEVAVVERRDDGRFFVETSLGTRFITKTIFIAAGVGSFQPRTLKVDGIDKFDGKQLFYRVKDPSRFHGRNLVIVGGGDSALDWTLDLVGKAESVVMIHRRDGFRAAPASVAKMKELCEQMEMQFLVGQIGGYEEKDGVLTEIKVTGADGVTRRLPVDDVLVFFGLSPKLGPIAEWGLDLERKQIKVDTEKFQTNIPGIFAVGDINTYPGKKKLILSGFHEAALAAFGAAPYIFPEKKIHMQYTTTSPKLHKVLGVESPVFD
What are the official names of this protein?
Ferredoxin--NADP reductase 2, FNR 2, Fd-NADP(+) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: FLVA_ASPFN
Sequence: MHDVWRTILSRFKQNTNAIKTRFDKYRALCKELGLQRDEWSESIFLDDLEKLLKLTAKFEMALMPSNGVDTHVNGVITKINGFNNGFDTHINGFDTRINGFHTHTNGFDRGLELWQIEERYRALAQLQSTLGSFFERACPGYDQSKIPWFFDPSYYQCQGVNYDRFASPDVRDREQQLLETLQLGSNQNPKLLLMSSGMASFTVIQQYVVQQLNYGDTVVVSPYIYFESFQPMRSQKSLTVVNAKGFDPESIIEAAERNNARAVFLDPMCNTVGLDTIDIRRFAHLVANRGGWADRLVIVDGTLVSGGMQLYDWFDGPHCPKVLYYESAHKYIQLGLDLIMCGYVVMPEDLVPAIQLIRQITGTVLYSRNASLLPPIDKTIFNFRMSRLTTNAEKLHRLLDAESRNMAEVTFPHHWRDYRWRHGGNVVTVRFHGEGLNKRSNLERCCDDILRAAEEEGVQMVKGASLGFSTTRIFVADAFFENTDPFLRISVGVQSEDIETVARAVLSGIKRYCMSAVPVNLDVGQRLYDAKFYIAMASMLEVRARYAKDRVVFMEGEWLVPILKALGAREEDFDALQQVSHHLGKDPTVDYRTIRNGLFYFNFENKAIQRFQKQRFTLTVQENYKRHDSGLPRDFPEVRGDLQYNTVLQALMVAKAFIMNKVDVEPRAHLDYSSPNFLCNVFNIRTFTEKNILGEPTLEGVHADGADHTMTTFLGCTNMRSDSGITFIHDQKEITGIPATEAQPSLIKHRFQHRHFLDSLLFADNEAKHSLTSVFQEDVSKRATRDMLLFLTRKPKLAGHSSGSVDAMEPHKTLPMNVPLWL
What is the function of this protein?
Bifunctional enzyme; part of the gene cluster that mediates the biosynthesis of flavunoidine, an alkaloidal terpenoid with a tetracyclic cage-like core connected to dimethylcadaverine via a C-N bond and acylated with 5,5-dimethyl-L-pipecolate (PubMed:31885262).  The tetracyclic core is synthesized by the terpene cyclase flvE and the cytochrome P450 monooxygenase flvD (PubMed:31885262).  The terpene cyclase flvE catalyzes the cyclization of farnesyl pyrophosphate (FPP) to form (1R,4R,5S)-(+)-acoradiene and the cytochrome P450 monooxygenase flvD is then responsible for oxidative conversion of (1R,4R,5S)-(+)-acoradiene into the tetracyclic cage present in the final product flavunoidine (PubMed:31885262).  In parallel, the N-methyltransferase flvH dimethylates L-lysine to give N,N-dimethyl-L-Lysin which is decarboxylated by flvG to afford dimethylcadaverine (PubMed:31885262).  The terpene cyclase-like protein flvF is the enzyme that attaches the dimethylcadaverine precusor at the C-7 of the tetracyclic cage to yield pre-flavunoidine (PubMed:31885262).  The cytochrome monooxygenase flvC hydroxylates the C-10 position of pre-flavunoidine whereas the NRPS flvI acylates the terpenoid core at the hydroxylated C-10 with dimethylpipecolate to yield final flavunoidine (PubMed:31885262).  The bifunctional enzyme flvA and the dehydrogenase flvB are responsible for the synthesis of the dimethylpipecolate precursor (PubMed:31885262).  The PLP-dependent lyase domain of flvA might use L-O-acetyl-homoserine and alpha-keto-isovalerate to form an intermediary ketone that can cyclize intramolecularly to yield an imine (PubMed:31885262).  The imine can be reduced by flvB to yield the 6-carboxylated pipecolate (PubMed:31885262).  The C-terminal alpha-KG-dependent oxygenase domain of flvA is then proposed to catalyze the decarboxylation to yield dimethylpipecolate (PubMed:31885262).
What are the official names of this protein?
Bifunctional enzyme flvA, Flavunoidine biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: SYC_FRACC
Sequence: MGLHLYDTRRRRVRPFEPLRPGHVGVYVCGPTVQAAPHVGHIRTALPFDLLRRWLVQSGRSVTFVQNVTDIDDKIIINADRDGTSVWELATRQTRAFDDAYRTLGILPPTIQPRATGHIPEMIALVSALVEGGYAYASGGSVWFRVGAFADYGALSHQRPDAMQPSVEAEPGKADPRDFALWKAARPGEPFWSSPWGDGRPGWHLECSAMAGKYLGPVFDIHGGGLDLVFPHHENERAQTVCAATARPASNAASADSPGPGGGEPGGGEPSSGEMARYWMHVGLLTTGGTKMSKSLGNSVLVADALDAVRPQVLRYHLLSAHYRSTLEYSAEALAESTAAHDRVETFVRNALDILGGPGEAAALAADEVVSSVAGAQPTVAGARPVPVPGPGGESRLTPRRAWSDFTIAMDDDLAVGRALAALFGAVSQGNQVLSKAHSRELAGWVDVTRRMLNIFGLDPHEQWPTAGAEFRPALDGAMQVVLDLRSAARARRDYAEADAIRSRLAAAGLIVEDTPEGQRWHLA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GXLT1_HUMAN
Sequence: MRRYLRVVVLCVACGFCSLLYAFSQLAVSLEEGTGGGGGKPQAAVASWLAGGGRGAVRGAGVAGPAAHPGVSDRCKDFSLCYWNPYWMLPSDVCGMNCFWEAAFRYSLKIQPVEKMHLAVVACGERLEETMTMLKSAIIFSIKPLQFHIFAEDQLHHSFKGRLDNWSFLQTFNYTLYPITFPSENAAEWKKLFKPCASQRLFLPLILKEVDSLLYVDTDILFLRPVDDIWSLLKKFNSTQIAAMAPEHEEPRIGWYNRFARHPYYGKTGVNSGVMLMNMTRMRRKYFKNDMTTVRLQWGDILMPLLKKYKLNITWGDQDLLNIVFFHNPESLFVFPCQWNYRPDHCIYGSNCQEAEEGGIFILHGNRGVYHDDKQPAFRAVYEALRNCSFEDDNIRSLLKPLELELQKTVHTYCGKIYKIFIKQLAKSVRDRYARSPKEK
What is the function of this protein?
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
What are the official names of this protein?
Glucoside xylosyltransferase 1, Glycosyltransferase 8 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
Protein: OST5_DICDI
Sequence: MALVPYTSPLDIVFYPVCAFLFCVIGFAFFATFIVSEMTTAKAQKNIFRELTLALIASMSLGLGLFFVLLAGGIYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5, Oligosaccharyl transferase subunit OST5, Transmembrane protein 258 homolog.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UXAB_YERPP
Sequence: MQTLNRRDFPGRSHPDKIIQFGEGNFLRAFVDWQIDLLNEHTDLNAGIVVIRPIDTDFPPSLSTQDGLYTAVIRGLNEQGEAVRESRLIRSVNREINIYRQFDDYLALARDANIRFMFSNTTEAGIAWNEADQFSDAPPSSFPAKLTRLLFERFEHFDGAADKGWVLLPCELIDYNGEALRELVLRYASHWQLPAAFTHWLTENNTFCSTLVDRIVTGYPRDEVAALQTELGYQDSFLDTAEYFYLFVIQGPQGLAQELRLDQLDLNVRIVDDIKPYKERKVAILNGAHTALVPVAYLSGLDTVGQTMDDAQISRFVEKTITEEIVPVLDLPEDELLSFSQAVLSRFRNPFIQHQLLSIALNGMTKFRTRILPQLLTYQQQKGQLPPRLTFALAALIAFYRGEREGQTYPLQDDAHWLERYSTLWNGVKHGDIALAELVNRVLSDANHWGQDLTAVPQLANQVTEQLQTILSRGMRAAVAAYS
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: ATL4_HUMAN
Sequence: MENWTGRPWLYLLLLLSLPQLCLDQEVLSGHSLQTPTEEGQGPEGVWGPWVQWASCSQPCGVGVQRRSRTCQLPTVQLHPSLPLPPRPPRHPEALLPRGQGPRPQTSPETLPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGPWGTGGTPHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISSPPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQMPAPPHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPCSQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLERSPQDPS
What is the function of this protein?
Positive regulation of apoptosis.  May facilitate FBN1 microfibril biogenesis.
What are the official names of this protein?
ADAMTS-like protein 4, ADAMTSL-4, Thrombospondin repeat-containing protein 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Colocalizes with FMN1 microfibrils in the eye ECM.
Protein: NUOI_PELUB
Sequence: MKISRIFKTIFLLDFLGGLNIAIKEIFKSKKTINYPFEKGKISPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIESSERADGSRKTTRYDIDMMKCIYCGLCEESCPVDAIVQGPNFEFSTETREELYYNKEKLLDNGDRWENVLAANIKADNSHR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DTD_PSEF5
Sequence: MKGLLQRVRGARVEVAGDIVGAVDQGLLVLVAVEPEDTRASADKLLHKLLNYRVFSDAEGKMNLSLADVQGGLLLVSQFTLAADTKSGLRPSFSTAAPPALGEELFDYLVVKAQQLHGKVASGRFGADMQVHLVNDGPVTFLLQT
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STET_BACSU
Sequence: MHTEDNGLKKEIGLLFALTLVIGTIIGSGVFMKPGAVLAYSGDSKMALFAWLLGGILTLAGGLTIAEIGTQIPKTGGLYTYLEEVYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLMANLFGWGSGLSKVIGIIAVLFLCVINIIGTKYGGFVQTLTTIGKLIPIACIIVFGLWKGDQHIFTAVNESISDMNFGAAILATLFAYDGWILLAALGGEMKNPEKLLPRAMTGGLLIVTAIYIFINFALLHILSANEIVTLGENATSTAATMLFGSIGGKLISVGIIVSIFGCLNGKVLSFPRVSFAMAERKQLPFAEKLSHVHPSFRTPWIAISFQIALALIMMLISNPDKLSEISIFMIYIFYVMAFFAVFILRKRAKGEKRAYSVPLYPFMPILAIAGSFFVLGSTLITDTMSCGLSILIGLAGLPVYYGMKKRKAS
What is the function of this protein?
Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids.
What are the official names of this protein?
Serine/threonine exchanger SteT.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCA1_AJECN
Sequence: MYSGRSGAPPPAHSPYPNSYNHGPPGHSAGHNVPPPPPTQPVQFGHGAPQGYSFQYSNCTGKRKALLIGINYFGQRGQLRGCINDVKNMSTYLNQNFGYAREDMVILTDDQQNPMSQPTKANILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGNDEVIYPVDFRSAGHIVDDEMHRIMVKSLLPGVRLTAIFDSCHSGSALDLPYIYSTQGILKEPNLAKEAGQGLLSVVSAYARGDVSGMLSTVGGLIKKATSGDASHSKARQTKTSPADVIMWSGSKDNQTSQDATIAGEATGAMSWAFITALKKNPQQSYVQLLRSIRDELATKYSQKPQLSCSHPLNTDLLYVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: PROBA_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLVEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1296_MYCBO
Sequence: MVLARPDAVFAPARNRCHVSLPVNAMSLKMKVCNHVIMRHHHMHGRRYGRPGGWQQAQQPDASGAAEWFAGRLPEDWFDGDPTVIVDREEITVIGKLPGLESPEEESAARASGRVSRFRDETRPERMTIADEAQNRYGRKVSWGVEVGGERILFTHIAVPVMTRLKQPERQVLDTLVDAGVARSRSDALAWSVKLVGEHTEEWLAKLRTAMSAVDDLRAQGPDLPA
What are the official names of this protein?
Uncharacterized protein Mb1296.
Protein: PQQE_METNO
Sequence: MNAVTPTLPAPIGLLAELTHRCPLRCPYCSNPLELDKRSAELDTATWQRVLAEAAALGVLHIHLSGGEPTARQDIVEITRTCADLGLYSNLITSGVGAALGKLEALYDAGLDHVQLSFQSAEAGNAERIGGLKNAQAQKFAFAERVVALGLPLTLNAVIHRGNIDEVPTLIDLAVTLGAKRLEVAHTQYYGWAYVNRAALMPAKADVDRSIRVVEEARERLKGRLVIDLVVPDYYAKYPKACAGGWGRRLMNVTPAGKVLPCHAAETIPGLEFWNVQDHALADIWAHSPAFQAYRGTSWMKEPCRSCDRREKDWGGCRCQALALAGDAAATDPACSLSPLHAKIQALAIAESALEIAPDYQYRTIGGAPAVPQPEGASA
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: ERPA_COXBR
Sequence: MNALAQKTPSPPTLVFTEAAVRKVKGLIDEENNPYLNLRVFITGGGCSGFQYGFTFDEAINSDDLVIEKQLEEEDDDEGGTGQMALVKLLVDPLSLQYLQGAEIDYREDVSGAQFVIRNPNAKTTCGCGSSFAA
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SYFB_PHOPR
Sequence: MKFSESWLREWVKPAINSEELAHQITMAGLEVDEVAPVAGEFTGVKVGKVVECGQHPDADKLQVTKIDIGEEALLDIVCGASNCRLGLTVAVATVGAVLPGNFKIKKAKLRGVPSHGMLCSFSELGIDVESDGILELPEGTALGMDVRELLELNDVAIDVDLTANRADCFSIRGLAREVGVLNRADVTEPVIDAVAPSIDDTVSVEIKATDACPRYLGRVVKNINVKAESPIWMQEKLRRCGIRSIDAVVDITNYVMLEQGQPMHAFDLSKIDGGIVVRLAEQGEKLTLLDGNETELNSNTLVISDHTKALAIAGIFGGKDSGVTTETTDVLLEAAFFAPDHIRGRARAYGLHTDSSLRFERGVDSTLQAAAMERATQLLVEICGGEVAPVNGSESEADLPKANVVALRRTKLDSLLGHEIPSEDVVEILTRLGCNVSVVDDSETTDAGWTATSPAWRFDIAIEQDLIEEVGRIYGYDNIPNQAPVAALKMNDHKEANQPLKRVRDLLVDRGYHEAITYSFVEPEQQKLVVPGVEPLILPFPISADMSAMRLGLIQGLLNTVVHNQKRQQSRVRLFESGLRFIPEASAENGMRQEMMLAGVIAGTRGEEHWDIDTNTVDFFDLKGDLEAILELTANEKAYSFKALSSENKKQNPVLHPGQSAVIVVDAGLETEKEVGVIGTVHPELERKFGLNGRTIVFEIEWAAINTRVLPEAVAVSKFPANRRDIAVVVDEAAASGDIVKACIAAGGEFLTDAKLFDVYVGKGVEEGKKSLAIALSLQSVERTLEDADISGAVDSIVAVLAERFGASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_ECO27
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MHQE_BACSU
Sequence: MKTEGLHHVTAFARDPQENLRFYTEVLGLRLVKKTVNFDDPGTYHFYFGNQNGDPGTIMTFFPFQGSGQGTVGKGQAGRVYFSVPSGSLSFWKERLEKSGLSLEEKTLFGEKGLIFDDTEDLPLAIMEDAKSGKSEWTPDGITTNEAITGMKGVLLYSYDPQATIQLLTESFGYTKVAEEDQIVRLASSAAVGGVIDVHLHPEKRGVGGYGTVHHVAFRTKKKEQAKWLPIIAENHLPSSEILDREYFTSVYFREKGGILFEIATDEPGFMTDETFAELGTSLKLPEWLEKHRQQITDILPEL
What is the function of this protein?
Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.
What are the official names of this protein?
Putative ring-cleaving dioxygenase MhqE.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_ECOLI
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDRCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAFA_CORJK
Sequence: MTAIRRRIMGLETEYGIANMQDSSRRLGPDEIARKLFAPVVEKHRSSNIYTENASRLYLDVGAHPEFATAECDSLHQLIAYDRSGDLMFHELADRAEQAVGGKVYLLKNNTDSLGNSYGCHENYLVSRDIPLKGLSKQLLPFLVTRQLICGAGKLAIPYPGAPNENFGPGYTMSQRADHVWEGVSSATTRSRPIINTRDEPHADSSKYRRLHVIVGDSNMSEVTTALKVGSTLLVLEMIEAGVALPDFEMANEIRSIREISRDFTGQVDIALRSGSTATPLEIQRAFYDAACAYLASREDPERGTPNAELTPVVDLWGRVLDCFDTGDFSPVSTEIDWVIKKSLLDRMAAARGLDPIDPRLAQIDLMYHDIHPTRGLFNVLARRGLARTLLAPETIEQAVRQAPPTTRAAVRGRFIAAVRANPELSYTVDWMRVKVNGEGGAEALLADPFANTSEDVDRIIESLESR
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.