PharMolix/UniProtQA huggingface dataset:
Protein: TVA40_HUMAN
Sequence: MNSSLDFLILILMFGGTSSNSVKQTGQITVSEGASVTMNCTYTSTGYPTLFWYVEYPSKPLQLLQRETMENSKNFGGGNIKDKNSPIVKYSVQVSDSAVYYCLLG
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 40.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RSMG_METFK
Sequence: MQQKLETGIRQLGLDLPAEVTEKLLAYLALLAKWNKVHNLTAVRDPEDMVTLHLLDSLSVLPHVPSGSLLDVGSGAGLPGIVLAICRPDLQVTTIDAVQKKASFMRQAKAELQIDNLQVVAGRVEQFEPEAPFDTVISRAFSEIALFVKLTRHLMAEDGLWLAMKGQMPQEELGAVALKPAKIMSLIVPGLDAQRHLVFLPARQF
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CENSY
Sequence: MRKNESQRETKETEVSVSVLLDGTGSTTVNTGQPFLDHLVSSLGKHAMFDIDLKASSRDGIVHHLVEDVAITLGGAIDKALGDRSGIMRFGHASVPLDESLSEAVVDLVKRPYHRIEMKIKRPEVEGIAKEDLEHFFDSLLRNLDCCIHLTVKYGNNDHHRVESAIKSLAVALRMAVSADPRREGPPSTKGSM
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGKB_PSEVC
Sequence: MKKVNLSSKWIISISLLIICDYVYLIRTNVNEQANAEATAHMHYKINNTKHSKGKLD
What are the official names of this protein?
Protein CgkB.
Protein: CH60_ACTPJ
Sequence: MAAKDVKFGNDARVKMLKGVNVLADAVKVTLGPKGRNVVLDKAYGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVVAVVEELKAISKPCETSKEIEQVGTISANSDETVGKLIAQAMEKVGKEGVITVEDGTGLDDALDVVEGMQFDRGYLSPYFINKPEAGTVELENPYIILVDKKISNIREILPVLEAVAKAGKPLLIVAEDIEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEELGQAKRVVITKDNTTIIDGIGDEAQIKARVAQIRQQIEDSTSDYDKEKLQERVAKLAGGVAVIKVGAATEVAMKEKKDRVDDALHATRAAVEEGIVPGGGVALVRAASKVATTLTGDNEEQNVGIKLALRAMEAPLRQIVTNAGEEASVVARNVKDGNGNYGYNAGTEQYGDMLEMGILDPTKVTRSALQFAASIAGLMITTECMITDLPKEEKLDPAAAMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_POLNA
Sequence: MHDPLGNPVLRNARRIVVKVGSSLVTNEGRGLDAIAIGQWCEQLAALIKDGREVIMVSSGAIAEGMKRLGWSLRPKAIHELQAAAAVGQMGLVQMYETKLRENGIGSAQVLLTHADLADRERYLNARSTLLTLLQLGVVPVINENDTVVNDEIKFGDNDTLGALVANLVEADALIILTDQKGLYTADPRKDPAAQFVHEAKAGDAALEAMAGGAGSSIGRGGMITKILAAKRAAGSGASTVIAWGREPEALIRLTQGEAIGTLLVAQTQKTQARKQWMADHLQLRGSVTVDPGAASMVQVGGKSLLPIGMTGVQGDFSRGDVIAVKDADGVEIARGLANYSSAEARLICRKVSSEFEKLLGYTGESEMVHRTNLILSR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH3B_HUMAN
Sequence: MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS
What is the function of this protein?
Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD(+)-specific ICDH subunit beta.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: METE_LACPL
Sequence: MTIINSNLGYPRLGEHREWKHLLEHFWKGQLDNVTFHATAKKLRLANLKKQRDLGVDYIPVADNSDYDHVLDTLVAFNAIPSRFGHFDHQLDLPDYYAIARGTDTAVAAEMTKWFNINYHYIVPEFDDVSFKLLDNRWLRYYQEAKQELGIDGKPVILGPISFLKLGKRHGQYLDDAAVNELLPQLLPLYQQVFEELATAGAKWIQLDEPTLVKTTTVAELAPYQTALEHLHAAVPSLKIELQTYFDSLDQYDKIVTWPIQALGLDLVHDHGENLAHLVDHGFPTDKILAAGIIDGHNVWASDLQAKLALVQQLRQIVTDDQLWLQPANSLLHVPITTKNETKADPVLLGGLAFADQKLAELHTLTVAANQGVAAVQAVFDHNQANLTALNQSSHRNNQSVRAAEAQLSNQKFERQAPFATRIKLQHDRLHLPLLPTTTIGSFPQSAQVRAKRAAWRKGNLTDADYQAFLHAETKRWIKLQEDLGLDVLVHGEFERTDMVEYFGQKLTGFYATQNGWVQSYGSRGVRPPVIFGDVAYTEPITVAESVYAQSLTDQPVKGMLTAPLTIINWSFVRDDIPRAQVQNQIALALRQEVQNLEKAGIKIIQVDEPALREGLPLKQRHWQAYLDEAVYSFKITTTGVQNDTQIHTHMCYSNFADIINTIKALDADVISIETSRSHGEIISAFEQTGYDQEIGLGVYDIHSPRVPSVAEIEANIQRALRVIDARQFWINPDCGLKTRQESETLAALKNMIAARNAIQAQLTTSIH
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: GPMA_STRA3
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIQAAGIEFDLAFTSVLKRAIKTTNLALEAADQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKQLSDDEIMDVEIPNFPPLVFEFDEKLNLVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: YQGF_BURP6
Sequence: MSAALSRDATLLAFDYGEKRIGVAVGNLLTRTARALVIVRNLNREHRFKAVGELIAEWKPDALVVGLPLHPDGAPHEMTQRAMRFGNQLNGRFNLPVNWVDERYSSVEARAGLRARGDAADRVDAEAARVILQQYLDGLPDHHEFN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP1A_ARATH
Sequence: MSAKKIVLKSSDGESFEVEEAVALESQTIAHMVEDDCVDNGVPLPNVTSKILAKVIEYCKRHVEAAASKAEAVEGAATSDDDLKAWDADFMKIDQATLFELILAANYLNIKNLLDLTCQTVADMIKGKTPEEIRTTFNIKNDFTPEEEEEVRRENQWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.  SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis.  SCF(TIR1) is involved in auxin signaling pathway.  SCF(COI1) regulates responses to jasmonates.  SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling.  SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock.  SCF(ORE9) seems to be involved in senescence.  SCF(EBF1/EBF2) may regulate ethylene signaling.  Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division.  Contributes to the correct chromosome segregation during tetrad formation.
What are the official names of this protein?
SKP1-like protein 1A, SKP1-like 1, UFO-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Associated to mitotic spindle and phragmoplasts during cell division.
Protein: NQRF_YERPA
Sequence: MEIILGVVMFTLIVLALTVMILFAKSKLVNTGDITVEINEDEDKSFTAPAGDKLLNMLSSHGIFVSSACGGGGSCGQCRVTIKEGGGDILPTELSHISKREAKEGCRLACQVNVKQNLKIELPEEIFGVKKWTCEVISNDNKATFIKELKLKIPDGDVVPFRAGGFIQIEAEPHTVKYADFDVPTEYRGDWDKFNLFRFESVVTEPTVRAYSMANYPEEHGIILLNVRIATPPPSVPDAPPGIMSSYIWSLKPGDKVVISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKISFWYGARSRREMFYEEDFDQLQAENDNFRWHVALSDPQPEDNWTGYTGFIHNVLLENYLKDHPAPEDCEFYMCGPPMMNAAVIKMLKDLGVEDENIMLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HEM6_ECOBW
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDRCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_BACTN
Sequence: MSRIVAIDYGRKRTGIAVSDTLQLIANGLTTVPTHELLNFIGGYVAKEPVERIIIGLPKQMNNEASENMKNIEPFVRSLKKRFPELPVEYVDERFTSVLAHRTMLEAGLKKKDRQNKALVDEISATIILQTYLESKRF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_HELPJ
Sequence: MKVGVYGASGRIGKLLLEELKGGYKGLELSSVFVRQKCETDFSSFSHAPLVTNDLKAFVKACECVVDFSLPKGVDHLLDVLLECPKILVSGTTGLEKETLEKMQKLALKAPLLHAHNMSIGIMMLNQLAFLTSLKLKDADIEIVETHHNLKKDAPSGTALSLYETCTKARGYDEKNALITHREGLRSKESIGIATLRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLKDKAAKKYEISEMFG
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_CLAM3
Sequence: MAKKSKIARNEQRKVIVERYAAKRLELKKALVDPNGTDESREAARAGIQRLPRDASPIRVRNRDGIDGRPRGNLSKFGISRVRFRDMAHRGELPGITKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: R14Z2_BACLD
Sequence: MAKTSMIVKQKREQKFKVREYTRCERCGRPHSVIRKFKLCRICFRELAYKGHIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z 2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: KDSA_CAMJJ
Sequence: MKKMILIAGPCVIESKDLIFKVAEQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLEEGLKILQSVKDEFGMKILTDIHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKVNIKKGQFLNPSDIKYSVKKALQTRGIEDEGYEAAQKNGVFVAERGSSFGYGNLVVDMRSLVIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEALCDGPNMLNLTRLKNCVNTLLEIQNIIKENK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_SALAI
Sequence: MGTIATNPEGITNPPIDELLEKTTSKYALVIFAAKRARQVNAYYSQLGEGLLEYVGPLVETTPQEKPLSIAMREINGGLLTAEPTDQP
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL7_BORBZ
Sequence: MALNKEDILTWLEGAKTMEVVDLVTAIEEKFGVTAAVAAGVGGAVSAGSADSEEQTEFDVILMSFGDSKINVIKEVRAITGLGLGEAKALVEAAPKAIKEGLSKSDAEELKKKLEAVGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EFP_SOLM1
Sequence: MLSTTDFRRGLKIEMDGVPYEIVDFLHVKPGKGGAFIRTKLKNMINGRVVENTFRSGEKMVKPDLESKDMQYLYRESEDFVFMDMESYEQMHAGAAQLGEKGGYLKDGMELKMLLYKGQPLDIDLPASVVLQVAETEPGVKGDTVSGATKPAQLETGITVNVPLFVNIGDRIKVDTRSGDYIGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_XYLFT
Sequence: MIQISDTAKSHFLKLIQREGVPGMGVRLSAVDPGTPRADARLEFADPSELVGDEWLIDCGDFTLYVASASVAWLDGAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGVEKTLMDRVHGVIAVRDATDHSTGAAPYISRDFSP
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: ARLY_ECO81
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEDLPLSELQKFSQVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2273_CLOBA
Sequence: MIITTTPAIEGKNILEYKGVVFGEVISGVNFIKDFAAGLSNFFGGRSNTYEDELIGAREKAMKEMENRAIQMGANAVVGVDIDYEVLGSDNGMLMVTASGTAVYCE
What are the official names of this protein?
UPF0145 protein CLH_2273.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: BSAA_STAAR
Sequence: METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL
What are the official names of this protein?
Glutathione peroxidase homolog BsaA.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: HSPB1_HUMAN
Sequence: MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
What is the function of this protein?
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975).  Plays a role in stress resistance and actin organization (PubMed:19166925).  Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
What are the official names of this protein?
Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: PHK_RHOPS
Sequence: MFDVLSDDLMQKMDAYWRAANYLSVGQIYLQDNPLLEQPLRIEHIKPRLLGHWGTTPGLNLLYVHLNRLISAHDLDMIYIIGPGHGGPGLVANSYLEGSYTERYPAIERNRNGLQRLFRQFSWPNGVPSHVSPETPGSIHEGGELGYSLAHAYGAAFDNPDLIVACIVGDGEAETGALATSWHSNKFLNPARDGAVLPILHLNGFKIANPTILARIGRQELTDLMRGYGYEPIVVEGDDPKLVHHTLAAALERALADIRAIQAAARHQGVTVRPRWPMIILRTPKGWTGPKQVDGKQIEGTWRAHQVPIASFKDPTHVQLLETWLRSYRPEELFDASGKFRDDLAALAPTGHRRMSANPHANGGELLQPLSLPDFHDYAVTQSGPGTVKAEATRVLGAFLRDVMKSNLDAKNFRLFGPDETASNRLDAVLEVTDKEWMAEIEDVDVALGPDGRVMEVLSEHLCQGWLEGYLLTGRHGFFSCYEAFIHIVGSMFNQHAKWLKTCDAIPWRRPIASLNYLLTSHVWRQDHNGLSHQDPGFIDHVVNKKASVVRVYLPPDANCLLSVADHCLRSRNYVNLIVAGKQPEWQWLDIDSAVRHCSAGAGIWHWASNGEDDPDVVMACAGDVPTLETLAAVMLLREYVPDIRVRVVNVVDLMVLQPSSEHPHGLDDKRFDEIFTVDKPVVFAFHGYPWLIHRLTYRRRNHFNIHVRGYKEEGSTTTPFDMVVLNDLDRYRLALDAIRRIPRLAGEVEAATARYWATMQRHKLYIGEHGDDMPEVRDWSWQG
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: RL18_CUPTR
Sequence: MMNKKDARLRRARQTRAKIAELKVNRLTVFRTNSNIYAQVFSECGTKVLASASTVEAEVRKELEGKGATAAAATVVGKRIAEKAKAAGVETVAFDRAGFRFHGRVKALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GPT_SCHPO
Sequence: MIESCFNVGIWATGLALLMNQGQSPLLSNVGLSVLAYKATAMFIPRVGPSFIKRGFSGKDMNKVEKYVIPETMGAVSALVYFMCMIIFIPVLFYKYLVPNHNPNLPSDGSVAEVAKSQFPHDLLGAYLSALLSILSVSLLGILDDLFDIRWRHKFFLPAIAAIPLLVVYYVDYGVTYVSVPSIVRPFLKRSLINLGFLYYFYMAAVAIFCPNSINIIAGVNGVEAGQSLVLALVIACNDLFYVLSPKNKDALRAHLLSLYLVLPLIGVTAGLLKYNWWPSRVFVGDTFCYFAGMVMAVVGILGHFSKTLMLFFIPQIFNFALSVPQLFGLVECPRHRLPKLNVKTGLLENSYTEFSLNEHPLPKKTLLTISIFEKLRLIRVEYDPSTGRPLRCTNFTIINFVLYHLGPMREDHLTICIMGLQLLTGIFGLIIRHFVAPLVYPEDNI
What is the function of this protein?
Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.