PharMolix/UniProtQA huggingface dataset:
Protein: DCR1_SCHPO
Sequence: MDISSFLLPQLLRKYQQDVYNIASKQNTLLVMRTGAGKTLLAVKLIKQKLEEQILIQESNLEHKKISVFLVNKVPLVFQQAEYIRSQLPAKVGMFYGELSIEMSEQLLTNIILKYNVIVITADLFYLFLARGFLSINDLNLIIFDECHHAIGNDAYARIMNDFYHRAKAVLSKKHFTLPRIFGMTASPFTGKKGNLYHRLYQWEQLFDSKAHVVSENELADYFCLPEESYVMYSNKLVVPPSDSIIKKCEETLQGCKLISRAVKTALAETIDMGLWFGEQVWLYLVDFVETKRLKKKALGKQLSDDEELAIDRLKIFVEDWKNNKYSDNGPRIPVFDSTDVTDKVFKLLELLKATYRKSDSVRTVIFVERKATAFTLSLFMKTLNLPNIRAHSFIGHGPSDQGEFSMTFRRQKDTLHKFKTGKYNVLIATAVAEEGIDVPSCNLVIRFNICRTVTQYVQSRGRARAMASKFLIFLNTEELLIHERILHEEKNLKFALSELSNSNIFDSLVCEERERVTDDIVYEVGETGALLTGLYAVSLLYNFCNTLSRDVYTRYYPTFTAQPCLSGWYCFEVELPKACKVPAAQGSPAKSIRKAKQNAAFIMCLDLIRMGLIDKHLKPLDFRRKIADLETLEEDELKDEGYIETYERYVPKSWMKVPEDITRCFVSLLYTDANEGDNHIFHPLVFVQAHSFPKIDSFILNSTVGPRVKIVLETIEDSFKIDSHLLELLKKSTRYLLQFGLSTSLEQQIPTPYWLAPLNLSCTDYRFLENLIDVDTIQNFFKLPEPVQNVTDLQSDTVLLVNPQSIYEQYAFEGFVNSEFMIPAKKKDKAPSALCKKLPLRLNYSLWGNRAKSIPKSQQVRSFYINDLYILPVSRHLKNSALLIPSILYHIENLLVASSFIEHFRLDCKIDTACQALTSAESQLNFDYDRLEFYGDCFLKLGASITVFLKFPDTQEYQLHFNRKKIISNCNLYKVAIDCELPKYALSTPLEIRHWCPYGFQKSTSDKCRYAVLQKLSVKRIADMVEASIGACLLDSGLDSALKICKSLSVGLLDISNWDEWNNYFDLNTYADSLRNVQFPYSSYIEETIGYSFKNKKLLHLAFIHPSMMSQQGIYENYQQLEFLGDAVLDYIIVQYLYKKYPNATSGELTDYKSFYVCNKSLSYIGFVLNLHKYIQHESAAMCDAIFEYQELIEAFRETASENPWFWFEIDSPKFISDTLEAMICAIFLDSGFSLQSLQFVLPLFLNSLGDATHTKAKGDIEHKVYQLLKDQGCEDFGTKCVIEEVKSSHKTLLNTELHLTKYYGFSFFRHGNIVAYGKSRKVANAKYIMKQRLLKLLEDKSNLLLYSCNCKFSKKKPSDEQIKGDGKVKSLT
What is the function of this protein?
Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation, accurate chromosome segregation, centromere cohesion and telomere function during mitosis and meiosis.  Digests double-stranded RNA (dsRNA) producing 21 to 23 bp dsRNAs, so-called interfering RNAs (siRNA).  Required for both post-transcriptional and transcriptional gene silencing.  Required for silencing at the centromeres and for initiation of transcriptionally silent heterochromatin at the mating type locus.  Promotes histone H3 'Lys-10' methylation necessary for centromere function.  Required for recruitment of swi6 and cohesin to an ectopic dg repeat.
What are the official names of this protein?
Protein Dicer, Cell cycle control protein dcr1, RNA interference pathway protein dcr1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL21_KOSOT
Sequence: MYAIIEASGKQYKVEEGITLFTEKLKDFAEGDQVVFDRVLLLKDDSGVKVGKPYLENVKIVGKVVRHGRGKKIRVVKFRPRKNYHRVKGHKQWFSEVLIEKIEY
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PETG_CYACA
Sequence: MVEVLLTGIVLGSIFITLLGLLAAAKLQYNRKKTN
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYM_METJA
Sequence: MRYLITTALAYTNGPLHLGHARSTYIPADIIYKYLKLRGEDVIHVGGTDNHGVPITLTAEKEGKSPEEIVEKYHNEIKEDLDLLGVEFDAFGKTHSQIHIETAQEFYLKLKENGYIYEKEIEQFYCPNCKKFLPDRYVEGICPYCGGEARGDHCEVCGRHLEPFELKDPYCVICKGKPEIRKTKHHFFKLSALKKELEEYIKNAKEMPEHVKNMALNWIKELHDWDISRDISWGVPIPGTNQVMYVWLEAPIGYISFTKMLGEIWKKYWLEKDTKIYHFIGKDITVHHAVFWPGMLIAHGSFNLPTAVVSGGYLTLEGRKMSTSKRWVVWVKDFVKNFDADYLRYYLIMSAPLFKDCDFSFDDFKNKINNELINIIGNFTHRVLTFTHRKFKKVPIVDEDRLKEEDKELLKKCEETLEAVDKNIRSFKFRDALVNILHLAIEGNSYFQKMEPWAVDDEERLKEILYTCCKTVKTLVYLLYPYMPKKSLALLELMNEELDLELRGNELKKPKIIFKKIDNKKIEEMKKKLYENKKEETKGGEKMEQIDISYLEKIDLRVGEVVEAEDIPKSKKLLKLMVDLGDEKRQIVSGIKGYYKPEDLVGKKVIVICNLKPAKLCGVLSEGMILAAEDDEGNVSLLTVDKDIKAGSKVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAZ_ECODH
Sequence: MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: TPIS_YERPB
Sequence: MRHPLVMGNWKLNGSTHMVNELIAGLRKELSTVDGCGVAIAPPAIYLNQAKHELAGSRIALGAQNVDVNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYHQESDELIAKKFGVLKEIGLIPVLCIGESEAENEAGQTEAVCAKQLDAVLNTLGVKAFEGAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAVAAQVIIQYGGSVNDKNAAELFTQPDIDGALVGGASLKADAFAVIVKAAAKAKKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y494_PROMS
Sequence: MYSKELGINFFGNESNKKRQLNKIEILKKNIKNLKIFLIIAGTNTSQIPGISAAGINAKSRRKTALADAEFLLEGASKDHKYKLPLLNAGVTPALISHVCSKLINIYPVIVPLGIGAKPYFNHLDVEDRNLGPSNCLTTGKSMTKERVLNLYEKGLAIGKSLQQPVLISESVPGGTTTAQAVMEAFGLQVSNLVGSSLFKAPRELRRKVVKRGLFNANFKANFDSFDVVAAVGDPFQAFSMGLLIGARLAKQPVILSGGSQMLAIILLVLEFLDEKHKDEFIEDVFIATTGWLVKDNSLNDLVNLINEKYDVKLLGLASPLNFKSSKYKELRDYELGHVKEGVGAGGISLLAFLDGFKNEEIVSLCQLNLEMMKDLGQISLEKDC
What are the official names of this protein?
UPF0284 protein A9601_04941.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: KA127_LYCMC
Sequence: MSNMPVLIITLLLFSMYISTAAQKPTEIKCRYPADCHIMCRKVTGRAEGKCMNGKCTCYY
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 12.7.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 12 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZIPA_ACTP7
Sequence: MELHILFFILAGLLIAVLIGFSLWSARREKSRIFSNTFSTRPPSTPINNIVSDVPPSLNPQSYAQTTGQHGETEADNPVQIQQEVESSLREIKINLPGQDSAAYQSKVEETPIYSGQPVLPVQPQYQTQVQYQTQPQHIEPAFTQAPQSPIAEATSVLEQSVEELERQAAQGDVDIYSDASVRVELAKNSMQADSVAEQKPVAENNMITLYVVAPEGQQFRGDYVVQSLEALGFQYGEYQIFHRHQHMGNSASPVIFSVANMMQPGIFDLTKIEHFSTVGLVLFMHLPSEGNDVVNFKLLLKTTENLAQALGGFVLNEHREIFDENSRQSYLARVS
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: Y2081_LISIN
Sequence: MTENKPSEETNELKDLVVEKEFNQTLDDLLANPFGSDGESAASIVNNETDAAPRLVDMLTETNKKQALELSKQIEPGNQAAILGYGAPAQAKLHDFSHSMLAHVQKQDVGPIGDIISDLMFRLQEADPDELAARNKNVFTKMFHRVKQSINEITSKYQKIGTQIDRIALKLEHSKKRLMEDNSFLEQLYDKNKDYFQALNIYIAAGELKLEEINTKMLPELRKKAEQTGDQMDYQEVNDLTQFADRLDKRVYDLRLSRQITIQQAPQIRLIQNTNQALAEKIQSSIMTAIPLWKNQVAIALTLLRQQQAVAAQRQVSETTNELLKRNADMLKTNAIETARENERGIVDIETLKETQSSLIETLQETLKIQQEGRAKRAVAEKELVTMEQELKERLLEMK
What are the official names of this protein?
Uncharacterized protein Lin2081.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: ISPE_THEMA
Sequence: MVENIGSGSAELVSYAKLNLYLDVLGKRSDGYHEIVGLFQTISLHDTLTVEICDRGFYLESSVALPSDNTIKRAWEMFRKNTGKEFGLKVTLKKEIPVGSGLGGGSSNAAAVLRYLGEVFKIPLEDLLNIAAQVGSDVPFFLYGGTALVRGRGEIVEKLEDIEGYSVDLFFPGIHSSTKEMYLSLTPEMYRKGPGRVEELHRAYLERNYEKIKELSYNVFEKVFLEKHPEVMDGLRNFGDGSIVKMMTGSGSVFFALYPLDKGNYSFVGGV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: BCL2_RAT
Sequence: MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDTGDEDSAPLRAAPTPGIFSFQPESNRTPAVHRDTAARTSPLRPLVANAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
What is the function of this protein?
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells.  Regulates cell death by controlling the mitochondrial membrane permeability.  Appears to function in a feedback loop system with caspases.  Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).  Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function.  May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
What are the official names of this protein?
Apoptosis regulator Bcl-2.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm.
Protein: CH60_SULSY
Sequence: MAAKKLVYGDEARAKLKAGVDKLANAVKVTLGPRGREVILEKKWGSPVVTKDGVSVAKEIELTDPYENMAAQLVKEVASKTADVAGDGTTTATVLTQAIYEEGLKAIASGANPIYVKRGIDEAVKIIVEELKKISKPVTGRKEIEQVATISANNDPEIGKIIADAMEKVGKDGVITVEESKSAETVLEVTEGMQFDRGYLSPYFVTNAEKMEAVLENPYILIYEKKVGNIRELLPVLEKVVQTNKPLLIIAEDVEGEALATLVVNHIKGVLRVCAVKAPGFGERRKAMLQDIAILTGGTAITEDLGIKLESVDLDMLGKADKVVVDKDNTTIIGGKGNPEDIKARIEQIKKQIETTTSEYDKEKLQERLAKLAGGVAIIKVGAATEAELKEKKDRVDDAVHATKAAVEEGIVPGGGIAIFRASRALCNIKEENTDKAWGIKIVKNACKVPLKQIAYNAGFEGSVIIEKIKDVDNVNYGFDAATGEYVDMVEAGIIDPTKVVRTALQNAASIAGTMLTAECLVAEIKEKEEKLPGAGGGMGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_ECO8A
Sequence: MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRAVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: UVRC_KLEP3
Sequence: MSDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVALIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPVRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQSLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFEAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFSLGDKTLLAESLSELAGRRINVQTKPRGDRARYLKLARTNAATALTTKLAQQSTIHQRLQALATVLELPAVKRMECFDISHTMGEQTVASCVVFDSNGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDENKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAISGHRKKRAKVKSTSSLETIEGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHGLAEKIFYSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_DACTR
Sequence: MINLRKTHPLMKIINHSFIDLPTPSNISAWWNFGSLLGVCLIIQILTGLFLSMHYTSDTLTAFSSVVHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPSGIDPNADKIPFHPYYTIKDIMGLTIMILALLTLALFHPDVLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALLASILILLVMPFLHTSKQRSMMFRPISQTLFWLLTANLATLTWIGGQPVEEPYIIIGQAASITYFLIILVLMPMAGLLENHMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYDND_RHIL3
Sequence: MHRYRSHTCAALRKSDVGSTVRISGWVHRVRDHGGVLFIDLRDHYGITQVVADPDSPAFQMAETVRGEWVIRIDGLVKARTEDTVNKTMATGEIELYAQEIEVLSAAKELPLPVFGEPDYPEDVRLKYRFLDLRRETLHRNIVKRTQVISAMRREMGNVGFTEYTTPILTASSPEGARDFLVPSRIHPGTFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEDVWNTMGPLMTSIFEEFAEGKPVTKEWPRIPYDEAIRKYGSDKPDLRNPIVMQAVTEHFAGSGFKVFAGMIASNPKVEIWAIPAKTGGSRAFCDRMNAWAQSTGQPGLGYIFWRKEGDKLEGAGPLAKNIGEERTDAIRTQLGLDDGDACFFVAGDPAKFYKFAGEARTKAGEELNLVDRDRFELCWIVDFPFFEWSEEDKKVDFAHNPFSMPQGGLDALQNQDPLTIKAFQYDAVCNGFEIASGSIRNQSPETMVAAFEKVGLSQQDVEDRFGGLYRAFQYGAPPHGGAAFGIDRIVMLLVGAKNLREISLFPMNQQAQDLLMGAPSPAAPTQLRELSIRPIPPVKKD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_VANPO
Sequence: MWRNGIVYRAVKNFVRHNSTNNAAKNLKSIKVEDIQNRIENIPIENYRNFSIVAHIDHGKSTLSDRLLEITGVISKTEGTSGQRVLDKLEVEKERGITIKAQTCSMIYNDKRNGQDFLLHLIDTPGHVDFRDEVSRSYKACNGAILLVDASKGVQSQTVANFYLAYSMGLKLIPVINKIDLNVAEVEKTAGQIESTFEMSQDEIIKVSSKSGINIQEKLLPAVIDRIPPPTGIKNKPFRALLVDSWYDSYLGVVLLVHVVDGSIKKGDKISSAITQMKYEIKEIGIMHPDRVNTGKLTTGQVGYIVPGMKNSQDAKIGDTFMKVGLESQTEILPGFEETKPMVFVGAFPADGVEFKALDDDINRLVLNDKSVTIEMENSNALGQGWRLGFLGSLHASVFKERLEKEYGSQLIITQPTVPYLIEYEDGTIKEVTNPNEFPTNRKAKGVKSIANVQEPYVEAIMTLPDEYLGNVITLCDNHRGKQVEIKYMDSGQSNAIKQVMLRYEIPLFELVDNFFGRLKSVSQGYATLDYEDIGFRPSDIVKLELLINGTTIDAITSILHRSKVNKVGTEWVKNFKKYVKSQQYEVVIQARINNSKIIARETIKARRKDVLAKLHASDITRRKKLLVKQKEGKKKLKMRSIGNIQINTDAYQEFLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SURE_HAEIE
Sequence: MRILVSNDDGFHAEGIQVLATELRKIAEVIIVAPDRNRSAASSSLTLVEPLRPRHLDNGDYCVNGTPADCVHLALNGFLSGQVDLVVSGINAGCNMGDDTIYSGTLAAALEGRHLGLPAIAVSLDGRQHYETAARVVCDLIPKLHHQLLNLREIININVPDLPFEELKGYKVCRLGYRASSAEVIKQRDPRDETIYWIGPSALPEDESEGTDFYAVKNGYVSITPIQADLTAYHSLLSLQNWLDQEFTK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CAMHC
Sequence: MRHKNGYRKLGRTSSHRAALLKNLTIAIVKNGKIETTLEKAKELRSYVEKLITRARKGDFNAHKFVFAALQDKEATNMLVNEVAPKFATKNGGYTRIIKTRTRRGDAAEMAYIELINE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MOG_HELPJ
Sequence: MQTIHIGVLSASDRASKGVYEDLSGKAIQEVLSEYLLNPLEFHYEIVADERDLIEKSLIKMCDEYQCDLVVTTGGTGPALRDITPEATKKVCQKMLPGFGELMRMTSLKYVPTAILSRQSAGIRNKSLIINLPGKPKSIRECLEAVFPAIPYCVDLILGNYMQVNEKNIQAFRPKQ
What is the function of this protein?
Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor.
What are the official names of this protein?
Molybdopterin adenylyltransferase, MPT adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: PATO_PENEN
Sequence: MRLHQSPPRLLVCILSVLQVSAGLSSNCRCMPGDSCWPSLNDWARFNTSIGGRLVDTQPLGQPCHDPFYTASECNELKQQWTHPELHDASSSSIMSAAVANETCDAFTPRSKPCTLGAMVRYAVNASSPDDFVQTIRFSQERNIRLVIRNTGHDYAGKSTGAGALSIWTHSLKEIDFLNYTSAHYTGPAVRMTAGIQGTDINPAAHKKGLVIVGGECATVGPVGGFTQGGGHSALSSRFGLAADQVLEWEVVDGMGRLLTASPTQNPDLYWALSGGGGGTFGVVYAVTVKTFPDFAVTGVVLQFENIDPSSNRFFEAVGHYHRHLPTYTSAGGMAIAQITNSSFLLTPLTLPAYTAAATKKLLGPFLQDLHQLNISYTLNVTESASYFQHYMKLIEPNPTQLVQNAQYGGRLLPLDLIERNNSQLTDAVQKLTADGVTFVGIGLNVSSSVTGDIWNSVLPGWRTAAMTVILTTSWPLGANLTKMKILADKMTTKWVPILTALSPESGCYMSEADPQQPDWKQTFYGRNYDSLYAIKTKYDPLQTFYATTAVGSEDWQVEAGGRLCQATRKN
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (PubMed:30100914, PubMed:25625822, PubMed:30680886).  PatO acts with patJ in the vacuole to convert gentisyl alcohol to isoepoxydon (PubMed:30680886).  The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units.  The 6-methylsalicylic acid decarboxylase patG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (also known as 3-methylphenol).  These first reactions occur in the cytosol.  The intermediate m-cresol is then transported into the endoplasmic reticulum where the cytochrome P450 monooxygenase patH converts it to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI.  The oxidoreductases patJ and patO further convert gentisyl alcohol to isoepoxydon in the vacuole.  PatN catalyzes then the transformation of isoepoxydon into phyllostine.  The cluster protein patF is responsible for the conversion from phyllostine to neopatulin whereas the alcohol dehydrogenase patD converts neopatulin to E-ascladiol.  The steps between isoepoxydon and E-ascladiol occur in the cytosol, and E-ascladiol is probably secreted to the extracellular space by one of the cluster-specific transporters patC or patM.  Finally, the secreted patulin synthase patE catalyzes the conversion of E-ascladiol to patulin (PubMed:30680886) (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase patO, Patulin biosynthesis cluster protein O.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole lumen.
Protein: PYRC_ARATH
Sequence: MIKTLVSPYSGFGSQKLKFDRSSEKVKTRAVRMELTITQPDDWHLHLRDGDLLHAVVPHSASNFKRAIVMPNLKPPVTSTAAAIIYRKFIMKALPSESSFDPLMTLYLTDKTLPEEIRLARESGVVYAVKLYPAGATTNSQDGVTDLFGKCLPVLEEMVKQNMPLLVHGEVTDPSIDVFDREKIFIETVLQPLIQRLPQLKVVMEHITTMDAVNFVESCKEGSVGATVTPQHLLLNRNALFQGGLQPHNYCLPVLKREIHREAIVKAVTSGSKKFFLGTDSAPHERSRKESSCGCAGIYSAPIALSLYAKVFDEAGALDKLEAFTSFNGPDFYGLPRNSSKITLKKSPWKVPDVFNFPFGEIVPMFAGETLQWQPLK
What are the official names of this protein?
Dihydroorotase, mitochondrial, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PXK_MOUSE
Sequence: MAFMEKPPAGKVLLDDTVPLTAAVEASQSLQSHTEYIIRVQRGISAENSWQIVRRYSDFDLLNNSLQITGLSLPLPPKKLIGNMDREFIAERQRGLQNYLNVIMANHVLSNCELLKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCVHPYIYRVTFATASESSALLIRAFNEKGTLKDLIYKAKPKDPFLKKYCNPKKTQGLELQQIKTYGRQILEALKFLHDKGFPYGHLHAANVMLDGNTCRLLDLENSLLGLPSFYRSYFTQFRKINTLESVDVHCFGHLLYEMTYGRPPDSVPVDSFPPASSLAVVAVLESTLSCEACKNGMPTVSRLLQMPLFSDVLLTTSEKPQFKIPTKLKEALRIAKECIEKRLTEEQKQIHQHRRLTRAQSHHGSEEERKRRKILARKKSKRSAVENSEEQPVKHSNSNNSAGSGASSPLTSPSSPTPPSTAGLSSALPPPPPPPPPPPPPAGPSPTSATEMPAPFLPQPVNGVNRGALLSSIQNFQKGTLRKAQTCDHSAPKIG
What is the function of this protein?
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission.  May not display kinase activity.
What are the official names of this protein?
PX domain-containing protein kinase-like protein, Modulator of Na,K-ATPase, MONaKA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane.