PharMolix/UniProtQA huggingface dataset:
Protein: TEG6_EHV1K
Sequence: MLPANRAEHSSDAEPRDIGSHGRNHGGCYSSDCKLGLLVDISNVVSPLPLDLTWSSWETTSQPARSRSYLNTRTYTIRACCDLQTRLHAFFIGVFEKRDPEKQILLPDLTNFKCILNNPRIMQELATEHSVCSAPFSAATQYDCDEDGEESTINGLCFHCHCKTPFSLECWQAANSAQAKILSVARGITSAKERQRENKR
What are the official names of this protein?
Tegument protein UL55 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL55 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus matrix.
Protein: GOP1_CAEEL
Sequence: MFRKLGSSGSLWKPKNPHSLEYLKYLQGVLTKNEKVTENNKKILVEALRAIAEILIWGDQNDASVFDFFLERQMLLYFLKIMEQGNTPLNVQLLQTLNILFENIRHETSLYFLLSNNHVNSIISHKFDLQNDEIMAYYISFLKTLSFKLNPATIHFFFNETTEEFPLLVEVLKLYNWNESMVRIAVRNILLNIVRVQDDSMIIFAIKHTKEYLSELIDSLVGLSLEMDTFVRSAENVLANRERLRGKVDDLIDLIHYIGELLDVEAVAESLSILVTTRYLSPLLLSSISPRRDNHSLLLTPISALFFFSEFLLIVRHHETIYTFLSSFLFDTQNTLTTHWIRHNEKYCLEPITLSSPTGEYVNEDHVFFDFLLEAFDSSQADDSKAFYGLMLIYSMFQNNADVGELLSAANFPVLKESTTTSLAQQNLARLRIASTSSISKRTRAITEIGVEATEEDEIFHDVPEEQTLEDLVDDVLVDTENSAISDPEPKNVESESRSRFQSAVDELPPPSTSGCDGRLFDALSSIIKAVGTDDNRIRPITLELACLVIRQILMTVDDEKVHTSLTKLCFEVRLKLLSSIGQYVNGENLFLEWFEDEYAEFEVNHVNFDIIGHEMLLPPAATPLSNLLLHKRLPSGFEERIRTQIVFYLHIRKLERDLTGEGDTELPVRVLNSDQEPVAIGDCINLHNSDLLSCTVVPQQLCSLGKPGDRLARFLVTDRLQLILVEPDSRKAGWAIVRFVGLLQDTTINGDSTDSKVLHVVVEGQPSRIKKRHPVLTAKFIFDDHIRCMAAKQRLTKGRQTARGLKLQAICSALGVPRIDPATMTSSPRMNPFRIVKGCAPGSVRKTVSTSSSSSQGRPGHYSANLRSASRNAGMIPDDPTQPSSSSERRS
What is the function of this protein?
Regulator of mitophagy.
What are the official names of this protein?
Protein CLEC16A homolog.
What is the protein family that this protein belongs to?
Belongs to the CLEC16A/gop-1 family.
Protein: PYRE_SORC5
Sequence: MSAAGASERERLVALLRERSFEQKRVVLASGRESDFFIDCKQSVLTAEGHALVGSLMFEALGALPRCEAVAGVELGGCPLASAVSLTSFLRGRPLPALYVRKEVKDHGSRRLVEGDRGLVPGMPVAILEDVITTGGSTLKAVEKLRTAGASVVGVIALVDRLEGGAEAIRAAGLPVVAICTRRDFIPDNPPG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FOLD_LIGS1
Sequence: MVATILDGRMLSKKIRTNVSEKVSLLKQEGITPKLVVILVGEDPASQVYVRNKRKTAHALGIEAVDIRLPENVEEDELIRLIDELNSDGTVHGILVQLPLPKHINENKVTHRIIPEKDVDGFHPLNIGKLFMNIPGPLPCTPRGIMEFFKEYDIPVSGKRVVIVGRSNIVGRPMAALLVNSDATVTIAHSKTKNLAEVTKQADILIVAIGKGEFIDENYVKKGAVVIDVGMNRNNDGKLVGDVNMESVSKVASYITPVPGGVGPMTIAMLMKQTVELAERSVAGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RNPA_STRA1
Sequence: MKKTYRVKSDKDFQMIFSRGKNVANRKFVIYYLEKEQKHFRVGISVSKKLGNAVVRNAIKRKIRHVLLSQKTALQDYDFVVIARKGVEELDYQALEKNLIHVLKIAGLI
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ACDH_BURP6
Sequence: MKSKSSRTRVAILGSGSIGLDLMFKVKASEQFDLKFVVGRNANSDGLRLARSCNVETSSDGLDFLKAHEDAYDLVFDATSAAAHKVNNRFFSDAGKFVIDLTPAKVGRLCVPCINLDDMGAEQNVNLITCGGQASLPLAYALKQAVDEIDYLEVVSAIASRSAGIATRENIDEYMTTTEYALAKFSGAKKTKAILNINPAEPGVRMQTTLYAYARYRDFDRVRASVADMVEKVREYVPGYRLVVEPLESQGRITIGLTVRGRGDYLPEYAGNLDIINCAALAVASHRHATARLGATQ
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RL7_BACTN
Sequence: MADLKAFAEQLVNLTVKEVNELATILKEEYGIEPAAAAVAVAAGPAAGAAAVEEKTSFDVVLKSAGAAKLQVVKAVKEACGLGLKEAKDMVDGAPSVVKEGLAKDEAESLKKTLEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CLPP_BACFN
Sequence: MNAMVLDDVIKSQAGYLNPYILEERQLNVTQLDVFSRLMMDRIIFLGTQIDDYTANTLQAQLLYLDSVDPGKDISIYINSPGGSVYAGLGIYDTMQFISSDVATICTGMAASMASVLLVAGAKGKRSALPHSRVMIHQPMGGAQGQASDIEITAREIQKLKKELYTIIADHSGTSFDKVWADSDRDYWMTAQEAKEYGMIDEVLIKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BRASB
Sequence: MPQSPIPTTEVIIAADCWQDQPDAEDVIHRAILAAAERVDAEVGDAEIAVMLTDDAGIRTLNSNWRGIDKPTNVLSFPALQPTGPRGDDDAPRMLGDIAIAYETMRREADEEQKPFDHHLSHLTVHGFLHLIGYDHESDAEAEEMEALETEILAHLGVPDPYADRERLD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_UREPA
Sequence: MSKNNENIKHQNNDKVNNQVDKKETKNHNKQEFKYKELYEHELKKNKELQNINTLLKDKNQQLEEQISQLNQDFIKQLETKAKQAQQILEQKVNELEARHEAKVNDAVFKIFKFKMEPLLDAINHFTKIVNQNYDDPKIQAFIEGFKMFSQNMIDGLDNLKITKISPQVNDSLNDEIMEVFEVVENTNKPSMHVVEVISDGFKYNDKVIKFAVVKVAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_CROS5
Sequence: MTFIMTSLQTPAVPEHSLDRDCTTLSRHVLQQLQSFSPEAQDLSAIMNRIALAGKLVARRLSRAGLMADVLGFTGETNVQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDKPYYIPENCPIGRYTLLYDPIDGSSNVDINLNVGSIFAIRQQKEDDLDGEGNDLLKDGREQIAAGYIVYGPSTMLVYSIGHGVHSFLLDPSLGEFILAQENIQIPDHGPVYSTNEGNFWQWDDAIRDYTRYVHRHEGYTARYSGALVGDIHRILMQGGVFLYPGTVKKPEGKLRLLYESAPLAFLVEQAGGKASNGLKPILDVVPDKLHARSPLVIGSKEDVSLVESFIQDHQHRNHG
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_METEP
Sequence: MPDAVGAIDQGTTSTRFIVFDRRGTILAQAQREHEQIFPRPGWVEHDPREIWRNTHAVMREGLARAGLAPEDLAAIGITNQRETAVLWDRRTGEPLHDAIVWQDTRTDRSVAALARDGGRDRFRAVTGLPLASYFSASKLAWLLDHVEGARAKAEDGTALFGTIDSWLVWNLTGGPDGGLHVTDVTNASRTQLMSLATLDWDEAMLGVFRIPRAVLPTIVSSSAVLGEARDPFPGVPLGGILGDQQAALFGQTCFSAGEAKNTYGTGCFALMNTGPAPVASSAGLITTVAYRLDGRPPAYALEGSIAITGALVQWLRDNLGLIGASSEIEGLARSVEDNGGVYVVPAFSGLYAPHWRDDARGLIIGLTRYANRGHIARACLEATAYQTREVLEAMERDSGCPIAELRCDGGMTVNDLLMQFQADILDRPTLRPKVSETTALGAAYAAGLATGFWKTLEDLRDNWAVDKRWHPHIQAEERRALFAGWSRAVERSFGWVEENA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AROC_LISMO
Sequence: MRYLTAGESHGPGLTTIIEGLPAGMPLLAEDVNKELKRRQGGHGRGARMRIEKDQVQITAGIRHGKTLGAPVAMFVENKDWKHWETVMSIEPVPEKNEKSRRVSRPRPGHADLVGGMKYGHNDMRNVLERSSARETTVRVAAGAVAKKLLHELGIEVAGHVLEIGGTRANLTRDYAVAEIQETSEASPVRCLDGVAAEEMMQKIDDAKKNGDTIGGIVEVVVGGVPAGLGSYVQWDKKLDAKIARAIVSINAFKGAEFGVGFEAARKPGSEVMDEILWSKEDGYTRRTNNLGGFEGGMTNGMPIVVRGVMKPIPTLYKPLQSVDIDSKETFNASVERSDSCAVPAASVVAEAVVAWEVAVAVLEKFDGDRFDTLKKHVEEHRNLTKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NFI_KOSOT
Sequence: MKIRCLHDWNVSLEEAADIQRTLKGMLSFEFPAKKVSIVAGVDVSFPQKNLGLCVIVVMDDTLKVIESVYHTQEVHIPYVSGFLSFREGPIFIETVKKLKIVPDLFFFDGQGIAHPRGLGIAAHMGLLLEKPSLGVAKSHLFGSYNEPGRNKGDFSYMYNKTGEIIGTVLRTKKNTKPVFVSPGHMMDVDTAMSLTLKYTGKYRLPEPTRQAHILTQRLRKNHLLR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUR8_DROAN
Sequence: MNLCSSGATASTTSLSSTGQAERSGGGGVAGGGGISNGGGGGGGVTGSGGGGGGNTSDGLSEATHCFGGSGGGATASGPEETINAISPANGGGASGAQQPSGSNGQLHNENNAIMPPETRPKMVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPSTVKDCVQITELYLYSNKIGQLPPEIGCLVNLRNLALNENSLTSLPESLQNCNQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLTSVPATLKNCKCMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFTSYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRRLRILDLEENRIETLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQM
What is the function of this protein?
Acts as a Ras effector and participates in MAPK pathway activation.  Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
What are the official names of this protein?
Leucine-rich repeat protein soc-2 homolog, Protein Sur-8 homolog, Protein soc-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: RL21_XYLFT
Sequence: MYAVLVTGGKQYRVVQGETLRVEKLDVETGGDVTFNSVLLMGGSDGIHVGEALKDASVTAKVVAHGRARKVRIIKFRRRKHHMKHQGHRQYYTEIQITGISGPAKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TCMM_STRGA
Sequence: MPQIGLPRLVEIIRECAGDPDERDLDGDILDVTYQDLGYDSIALLEISAKLEQDLGVSIPGEELKTPRHTLHLVNTETAGEVA
What is the function of this protein?
Involved in the biosynthesis of tetracenomycin C (TCM C) (PubMed:9609708).  Part of a type II polyketide synthase (PKS) that catalyzes the synthesis of tetracenomycin F2 (TCM F2), a precursor of TCM C, from malonyl-CoA (PubMed:8248801, PubMed:9609708).  TcmM is an acyl carrier protein that serves as an acceptor of malonate from malonyl-CoA and acts as the tether for the substrates and intermediates of polyketide assembly (PubMed:1592832, PubMed:8248801).  The malonyl CoA-acyl carrier protein transacylase FabD (MCT) is required to catalyze the transacylation between malonyl-CoA and TcmM, although a relatively slow spontaneous self-malonylation of TcmM also occurs in a reaction without the MCT (PubMed:9609708).
What are the official names of this protein?
Tetracenomycin polyketide synthase acyl carrier protein, ACP, TCM PKS ACP.
Protein: TIM8A_MOUSE
Sequence: MESSTSSSGSALGAVDPQLQHFIEVETQKQRFQQLVHQMTELCWEKCMDKPGPKLDSRAEACFVNCVERFIDTSQFILNRLEQTQKSKPVFSESLSD
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim8 A, Deafness dystonia protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: ARGP_SALA4
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RIMO_HELPJ
Sequence: MQVKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDAKKADVILINTCGFIESAKQESIQTILNAAKDKKEGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDILIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEVEDLALKGYKDMTFIAQDSSSFLYDKGQKDGLIQLIRAIDKQQALKSARILYLYPSSTTLELIGAIEDSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLNAMKQVKESFIRSTIIVGHPEENESEFEELSAFLDEFRFDRLNIFAFSAEENTHAYSLEKVPKKIINARIKALNKIALKHQNHSFKALLNKPIKALVEHKEGEYFYKARDLRWAPEVDGEILINDSELTTPLKPGHYTIVPSAFKDNILLAKVLSPF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_XYLF2
Sequence: MSDSRGVLSISTSTTFQGLIQTLNRYWAEQGCVLVQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNLQELYLASLQALGIDPLVHDVRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEVTYGLERLCMYLQSCDNVYDLVWTYGPDGTPVTYGDVYHQNEVEQSAYNFEHANVTELLHTFDACEREAKSLVEAVLPLPAYEKVIKASHCFNLLDARRTISVTERQRYILRIRTLSQEVAKAYYAQREKLGFPNLRR
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ECO27
Sequence: MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLVHN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCBP2_BOMMO
Sequence: MNSSIEISSYRDQHFKGSRSEQEKLLKASSTLYMGNLSFYTTEEQIYELYSRCGDIRRVIMGLDKYKKTPCGFCFVEYYAREDAENCMRYINGTRLDDRIIRCDWDAGFIEGRQYGRGKTGGQVRDEYRTDYDGGRGGYGKIIAQKINPNTLER
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y929_TREPA
Sequence: MSFEDAVATGSTKVGTDATGKMTHSYRSDVNEFFPDAQDLDTVLRTAVGALSPVVKIERGFAIVRTDAEPSAPDFSDAATRERVFAHMARVERGTIERFLEEEAHTFSTRAKQGGFTAAAQSLNLDVHTSRSFPINFGNVDVLPALPRQSDPPLARIAYDEKFFSTAFALLPGQVSDPLILDSSVVLLQLHEEKSVDESVLATTGDSYAHHVRTWYPGYPLALLNTAKMPWAQESVVDTILAHPSFKDTFDNIFRR
What are the official names of this protein?
Uncharacterized protein TP_0929.
Protein: ARCA_BORT9
Sequence: MQYLKPISVFSEIGRLKRVLLHRPGEELENLTPSIMQRLLFDDIPYLEVARQEHNAFADILRNNGVEVVYIEDLISETISQCDSVKDQFISQFIFEAGIRTENKTQALKDYFYNMSVNDMISKMIAGVTRDDLKNYKSDSLNFLVNSEYPLIVDPMPNILFTRDPFASIGHGVTINRMQTRVRRRETIFAEYIFKYHPIYRDNVPIWYTRDEDTTLEGGDELVLSRDVLAIGISERTESESVEKVARKLFQQKTSFSTILAFQIPQSRAYMHLDTVFTQIDHTTFTSFISDDMKFTIYALTYDLGSGSIKVKSEKAKLEDILGFYLGSKVNMIKCAGGDLIHGAREQWNDGANTLAIAPGEVIVYFRNHVTNRLLEEFGIKVYKMPSSELSRGRGGPRCMSMPLIREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_THET2
Sequence: MEALAKEIGIPEGEYREIVQRLGREPNRVELLLFKVMWSEHCAYKNSRPLLKALPKEGEAVLQGPGENAGVVRVGEGWAVAFKIESHNHPSAVEPFQGAATGVGGILRDIMSMGARPIALLDSLRFGPPEEARSRYLLKGVVSGIAFYGNAIGVPTVGGDLYFHEGYRENPLVNAMCLGLLREEHLKRSRASLGRPIYYAGAKTGRDGIGGAAFASRELKEEKAEDRPAVQVGDPFLGKLLMEATLEAIELDLVEGVQDMGAAGLTSSLSELAHKSGLGVELHLDLVPTREEGMTPEELLLSESQERMVLVPKEGKEKALEEVFGRWGLDCVPVARTIPERVFRVLFRGEVVAEVPTEALAEAPTYVRVGREDPEVRRLRETPIPPLEADPQEVLRRLLASPNLASREAVYERYDHQVGTRTALLPGKGDAAVLWIKGTRLGVAAKVDQNPRYSRLHPRLGAMHALAEACRNVSVVGAKPLAYTDGLNLGSPETPEGYHELAETIAGLKEASEALGVPVVSGNVSLYNESGGKRIPPTAMVGVVGVLEVDKRAEMGFRRPGEVLLLIGEERGELGASEVLYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFPYGVGATVEVREEGLEALFGEAPSRVLFTVEKTRLQEATLLLEERGLPYRVLGETGGKSLTVLTPGGVLEWSLEELLSAWKAPLREVLDG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCN3_MOUSE
Sequence: MEEEARPAAGAGEAATPARETPPAAPAQARAASGGVPESAPEPKRRQLGTLLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVSMNRMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLRRIGKKNSILQRKRSEPSPGSSGGVMEQHLVQHDRDMARGVRGLAPGTGARLSGKPVLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSARRSAGSPASPLVPVRAGPLLARGPWASTSRLPAPPARTLHASLSRTGRSQVSLLGPPPGGGARRLGPRGRPLSASQPSLPQRATGDGSPRRKGSGSERLPPSGLLAKPPGTVQPPRSSVPEPVTPRGPQISANM
What is the function of this protein?
Hyperpolarization-activated potassium channel.  May also facilitate the permeation of sodium ions.
What are the official names of this protein?
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3, Hyperpolarization-activated cation channel 3, HAC-3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel HCN family.
Protein: MTGA_BURO0
Sequence: MVAVSGTQRTRTVSLARWAVYAGSVFAGAWLATQLFYLAQIALWSFVNPGSTAFMRTDAWRLSRDTPPAQIRHQWVPYDQISRNLKRALIASEDSTFATNNGYDVDAILQAWEKNKARGRIVAGGSTITQQLARNLFLSREKSYIRKGQELIITWMLETVLDKERIFEIYLNSVEWGRGVYGAEAAARYYYKIPASRLGAWQSARLAVMLPKPRWFDAHRGSAYQAQRAAVIARRMGAAELPQSE
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
Protein: XYNA_BACSU
Sequence: MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTGTYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVRQSKRPTGSNATITFSNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.