PharMolix/UniProtQA huggingface dataset:
Protein: CCNF_DANRE
Sequence: MKAGALHCRCAKCFSLPVRKRVRKRASAVSLLSLPEELLVFVLQCLSAEDLLSVRAVHSHLCDIIDTNASIWARVSFKDRWPAPDTVWLFERAAEKGNFEAAVKLGIAYLYNEGPLLSEEGRADLCGRMASRYLSLSESLRSPQAEPFIWLFIRPPWSVSGSCCKAVVFDRLQAECQTSPGRKGTLLYCLARVLQLFDDEEKRDEAELMLKESSRCGSLQSSYLLWAISRASSTADPGRYLQCMRTLRDYAARGCWEAQLAFVKSCGSANPLGLEPRACSELVSQFFQTGPSALRYQPHLQGQDITTKRYILVDWLVEVTTTKDFSSQVLHVTISCVDRYLHLRSVPKAQLQLLGIACMVICTRFISKEILTIREAVWLTDNTYQYEDLVHMMGEVISVLDGKIRTPTVLDYGEVLLSLLPVERRTAHLFSYICELSLLCSPATVPGPARLASAILLLTRALHNYVPVWPVQLEENTGFSKQDLVSCALTLYIKCFGQDVPKDYRHVSLTGVKQRFEDDSYQQISKDTVMGFKELCHVLEVPEVEPQVEVSSTSGQITEMHTFLSSPTSSSKRRRADSMQAHRGAFVATPTAELSNQEETLLGDFLDWSLDTSCSGYEGDRESEGEKDGEISTMEVQMELPLDCADRQTHCCLLSSDDTSLCEEDEQEPPTGGSKPWTRHLSSSSTSSSSSSCGFCTDRHSSGYSSIQSFPSPTGSSALVSPQNPPGVPSQRIRRQVKRKNTAAHSAGEAEQEDDAANLAFLSF
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  The SCF(CCNF) E3 ubiquitin-protein ligase complex is an integral component of the ubiquitin proteasome system (UPS) and links proteasome degradation to the cell cycle (By similarity).  Mediates the substrate recognition and the proteasomal degradation of various target proteins during G2 phase involved in the regulation of cell cycle progression and in the maintenance of genome stability (By similarity).  May play a role in motor neuron development and axonal outgrowth (PubMed:28444311).
What are the official names of this protein?
Cyclin-F.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localizes to the nucleus in G2 phase.
Protein: Y2629_SULIM
Sequence: MKIKDAVNMIRWKYREKIDDYVVIIIDRLTENGLKEISFSEIDDVDNNYLYLKSEENTVIPLHRVLMIKRKSDNALIWKR
What are the official names of this protein?
UPF0248 protein M1425_2629.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: ILVC_XYLFA
Sequence: MVNVSITTDYSRMLFMRNTTSTLKIAIIGYGSQGRAHALNLRDSGFDIIIGLRPGGPTEAKAQADGFTVQSPDQAAKHADLVAVLTPDMVQKKLYEEVLAPNIKQGACLLFAHGLNVHYGMITPRSDLDVVLVAPKGPGALVRREYEIGRGVPCIYAVHQDLSSHAEQLALTYAGGLGGARANIIKTTFKEETETDLFGEQAVLCGGVSSLVQAGFETLVEAGYQPEIAYYEVLHELKLIVDLFYEGGITRMLEFVSETAQYGDYVSGPRVIDGSTKERMKAVLKDIQDGTFTKHWIAEYQAGLPNYKKYKQADLEHPIEKVGKQLRAKMVWLNSEKTNDTTPPMSSKVV
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YIDC_CUPPJ
Sequence: MDIKRTILWVIFSMSLVLLYDNWQRANGHASMFFPSATQQQAASAPAASAAQGDVPKANATAGAAAPAAPGGAPQAAAQPTGEKIIVTTDEVRAEIDTAGGILSRLELLNEHEKDGKPVVLFERDTTRTYMARSGLIGGDLPNHTTVFTATPGPRTLDGADKLEVTLTADKNGVKFVKTYVFHKGSYVVDARFAVTNDGTAPVSPTLYMELARDGSKVEQSQFYSTFTGPAIYTDADKYHKITFDDIAKGKASTPAATTSGWVAMVQHYFASAWIPQAGKEHSFYVQQIDPNLYRVGIQQPLGQIAPGATVTTDARLFAGPQEERMLEKITPGLELVKDYGWLTILAKPLFWLLEKLHGFLNNWGWSIIALTVLIKLVFFPLSAASYKSMGKMKDLQPRMTSIRERHKGDPQKMNAEMMALYKTEKVNPLGGCLPIVIQIPVFIALYWVLLSSVEMRGAPWLGWIHDLSVPDPFYILPIVMAVSMFVQTRLNPTPPDPVQAKVMMIMPLVFSFMFFFFPAGLVLYWVVNNILSIAQQWQINRMLGKGKTAAVAKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS17_ECOK1
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DPO3B_MYCS2
Sequence: MATTTAGLTDLKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEDDGANGGSGPFPAAKTDYVYLLMPVRLPG
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAC1_TRAVI
Sequence: MSRFHSLLAFVVASLTAVAHAGIGPVADLTITNAAVSPDGFSRQAVVVNGGTPGPLITGNMGDRFQLNVIDNLTNHTMVKSTSIHWHGFFQKGTNWADGPAFINQCPISSGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPAADLYDVDNDDTVITLVDWYHVAAKLGPAFPLGADATLINGKGRSPSTTTADLSVISVTPGKRYRFRLVSLSCDPNYTFSIDGHNMTIIETDSINTAPLVVDSIQIFAAQRYSFVLEANQAVDNYWIRANPNFGNVGFTGGINSAILRYDGAAAVEPTTTQTTSTAPLNEVNLHPLVTTAVPGSPVAGGVDLAINMAFNFNGTNFFINGTSFTPPTVPVLLQIISGAQNAQDLLPSGSVYSLPSNADIEISFPATAAAPGAPHPFHLHGHAFAVVRSAGSTVYNYDNPIFRDVVSTGTPAAGDNVTIRFRTDNPGPWFLHCHIDFHLEAGFAVVFAEDIPDVASANPVPQAWSDLCPTYDALDPSDQ
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-1, Benzenediol:oxygen oxidoreductase 1, Diphenol oxidase 1, Urishiol oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVA_DINSH
Sequence: MIGRLSGVLVYRGRDHIVLDVRGVGYVVQCSERTLAGMPAPGGPVALFTELLVREDLLQLYGFPTLLEKEWHRLLTSVQGVGAKASMSILSTLGVDGVGRAIALGDWGALRKAQGVGPKIAQRVVNELKDKGPEVMAMGGTLEAALDGVIEDGMAASEGIEPPSAARPAVPSAASDQAGALSALVNLGYGQGEAASAVATAAGEGAVGETDIIRAALRLLAPKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GSTUO_ARATH
Sequence: MADEVILLDFWASMFGMRTRIALAEKRVKYDHREEDLWNKSSLLLEMNPVHKKIPVLIHNGKPVCESLIQIEYIDETWPDNNPLLPSDPYKRAHAKFWADFIDKKVNVTARRIWAVKGEEQEAAKELIEILKTLESELGDKKYFGDETFGYVDIALIGFHSWFAVYEKFGNVSIESECSKLVAWAKRCLERESVAKALPESEKVITFISERRKKLGLE
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U24, AtGSTU24, GST class-tau member 24.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CYB_MYOLV
Sequence: MTNIRKSHPLVKIINSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYMYTETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAAMVMXHLLFLHETGSNNPTGIPANADMIPFHPYYTIKDILGLLLMITALLTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIVPLLHTSKQRSMTFRPLSQCLFWLLTAXLFTLTWIGGQPVEHPYVIXGQXASILCFXIXXXLMXLTSLMENHLXXX
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KGUA_CLOP1
Sequence: MMNKIHKDNRGVLIVISGPSGAGKGTICKALLEKHDDIFISVSATTRNPRVGEVDGVNYHFLTKEEFKQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGVFIFILPPSMEELKQRIIKRGSETPESLMTRFKSAYKEINYVSKYNYAVVNDNVEDAVKKIEAILLAEKCRVDRLKENLLESKEDEMHEQLYD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMD2_MOUSE
Sequence: MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKSGKGKKKSKPVNKDRYISKMFLRGDSVIVVLRNPLIAGK
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: BTDD_PAPAN
Sequence: MRTFALLTAMLLLVALQAQAEARQARADEAAAQQQPGADDQGMAHSFTRPENAALPLSESAKGLRCFCRRGVCQLL
What is the function of this protein?
BTD-7 has antimicrobial activity against the Gram-negative bacterium E. coli ML35, the Gram-positive bacterium S. aureus 502a, and the fungus C. albicans 16820.
What are the official names of this protein?
Theta defensin subunit D, BTD-d, BTD-7 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family. Theta subfamily.
Protein: TFNPH_ASFM2
Sequence: MSCVHNNTSFPVQIEAYLKEVFEKYKELQESKDTSLTARFARVLKYYQFLIYSAFSDPKFGIGQGENTRGLLIYHQMGMGKTILSLSLAISLSHIYNPILIAPKSLHSNFQQSLLKLIKLLYPETTDHSKELQKISRRFRFVSLDAYNMGQQIIKAGGSLNGCLLIVDEAHNLFRGIINSANDKTNARQLYNNIMQAKNIRILFLTGTPCSKDPFEMVPCFNMLSGRILLPLHYERFYTAYVNKTTNSPLNADKLLNRLVGMISYAGNQNELNKLFPTELPLIIEKVEMSPEQYRQYLLARDVENAEKHASSGMYEKMNTAALCLPGSEQESGSSYYVRSRMISIFASEMLTVKEDEKLSEAVQQLPKEAFTENSSPKIACMLKNIKTSPGPVLIYSQFVELGLHVVARFLEIEGYQCLQPLKVLEEGHNTILLHKDGKDLMVKNFAEDEPTHTLVLSSKITRFTLITGKILSKERDMIQQLWNSPLNIHGEVIKILLVSKTGAEGLDLKYGRQVHILEPYWDKAREDQVKARIIRIGSHDALPPEEKTVQPFLYIAVANQKMFYSIPEGSQEQKTIDERFHERGLEKSHLNSAFRDLLKRAAIECAFNGESGCLMCQPTNALLFHENFERDLRLPNPCQPLVKTEVKAYSISYEGKQFFYQKNKEVGLGYTFYEYNPIIKAYIEIKPSNPLYIKLIKHVQAGTTV
What is the function of this protein?
Putative DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts.
What are the official names of this protein?
Termination factor NPH-I homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: COAD_PROMS
Sequence: MKILYPGTFDPLTNGHLDLIERAEKIFGNLVVAVLENTSKTPTFNLERRIIQIKNSLSHLPNIEVISYSGLTVDCANDLKANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNTNYSFLSSSLVKEVAKFGGEINHMVPPPVEKDLKEYFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y489_MYCLE
Sequence: MRSGLFGVLRWTAVGLVATLVASLALTACSGSAAGEIVYVVDGALGTYNTNTIVGAASAGAQAFARTLIGFGYHGPDGQIVADHDFGTITVVGGVPLVLDYQIADNAVYSDGKQVTCDDLVLTWAAQSGRFPGFDAATQAGYRDIANIECLAGQKKSRVFFVPDRSVVDYEQLFAATSMMPSHVIADQLNIDVTEALLTHNATLVEQIARLWNTTWDLKPAVDLRRFPSSGPYKIESVLNGGAVVLVANDRWWGLKATTKRITVRPQEADIQDRVNNRSVDVVDVAVGSSGSLATPDNYARIDSPSAGIEQLIFAPQGLLAAAAARRALALCTPRDVVARDAGLSIANSRLSPATEDAIAAADGAREAGQFSKADPAAAHDALSGETLPVRIGYQGPNARLAATVGTIAKACAVAGISVSSVTLDSSTDPSGPQALRDGKIDVLLASTGGATGSGSSGSSSMDAYDLHTGNGNNLSGYANAQVDNNIGALAVSADPAERVRLLADSAPVLWADMPTLPLYRQQRMLLMSKTMYAVTRNPTRWGAGWNMDRWALVR
What are the official names of this protein?
Uncharacterized lipoprotein ML0489.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2585c and M.bovis Mb2616c.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: LPXA_BRUAB
Sequence: MKETFIHPTALVEPGVELGQGVSVGPFCHVQSGAIIGNDCELMSHVVITGATTLGAGTKVYPHAILGCDPQNNKHKGGPTRLNVGVNCIIREGVTMHKGSDNARGYTSIGDNCSFLAYAHVAHDCDIGDYVTFSNNVMIGGHTSIGHHAILGGGAAVHQFVRVGHHAFIGGLAAVVSDLIPYGMAIGVHAHLGGLNIIGMKRSGMERKEIHNLRHAVRMLFDRTKPIRQRAQDVLAAIPDSPTVSDMISFINVDTKRAYCTPPLDAAHGGAGHDSDED
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_PSEP1
Sequence: MANTPSAKKRAKQAEKRRSHNASLRSMVRTYIKNVVKAIDAKDAEKAQAAYVLAVPVIDRMADKGIIHKNKAARHKGRLNGHIKALKEAAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NUOI_METPB
Sequence: MKLDQVARSLLLKEFVSGFFLAMKYFLKPKATINYPFEMGHRGPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTTRYDIDMVKCIYCGMCQEACPVDAIVEGPNFEFSVETREELLYDKQKLLENGDRWEREIARNIAIDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DDI1_CRYNB
Sequence: MRLTIIAPDSVHEHEVSPSLLIQDIINIVEATADLPPAVIVLTSDAGTPLTDPTRTLESYGLNGETATIFLTPTGPPVASSSSIPFPDADADIERMRLQALGNPSLMNDLRERDPETFAAIQGGTQSFKKALQLAQSRQRDAEFEKQRQIEALNADPYDIEAQKKIEEAIRMEAVLENMQHAMEYSPESFGNVTMLYINVEVNGHPVKAFVDSGAQTTIISPECAEQCGIMRLLDTRFAGMAEGVGTARILGRIHSAQIKLGSLYLPCAFSVLEGRSVDLLFGLDMLKRHQCCIDLSTNTLRINNTEVPFLSEHELPDKARRRGEAQVAGEMGDAAGQGVKAGVASPKIGKKTFPGEGHALGAGSSTGPGTATGSASATGARTGGTASVPSPSNRWKEDDIQTLVNLGAPRAQAIQLLEASGGNVDVAASMLFG
What is the function of this protein?
Probable aspartic protease.  May be involved in the regulation of exocytosis.  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Required for S-phase checkpoint control.
What are the official names of this protein?
DNA damage-inducible protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_STAA1
Sequence: MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPSEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_SHEWM
Sequence: MANAKELKQVLSGPIVSNNPIALQVLGVCSALAVTSKMETALVMTIALTAVCACSNLFISMLRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYDVAKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLSVGFVRELFGNGSLFGVEILSKISDGGWYQPNGLLLLPPSAFFLIGTLIWIIRTVKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COLDT_HUMAN
Sequence: MLLLNQTLATTEKQTALQAAEKFVDELCISYSAKKGRGYARKRQKNLLATLQAYKPQNPKDAPVNCDKCGKPGNVKNDCPGSMRKPARPCPICGGDHWRVDCPQRCRSLGPKPVSQVSNRIDGPQGSCPWL
What are the official names of this protein?
Putative uncharacterized protein COL25A1-DT, COL25A1 divergent transcript, Zinc finger CCHC domain-containing protein 23.
Protein: C74B2_ARATH
Sequence: MLLRTMAATSPRPPPSTSLTSQQPPSPPSQLPLRTMPGSYGWPLVGPLSDRLDYFWFQGPDKFFRTRAEKYKSTVFRTNIPPTFPFFGNVNPNIVAVLDVKSFSHLFDMDLVDKRDVLIGDFRPSLGFYGGVCVGVNLDTTEPKHAKIKGFAMETLKRSSKVWLQELRSNLNIFWGTIESEISKNGAASYIFPLQRCIFSFLCASLAGVDASVSPDIAENGWKTINTWLALQVIPTAKLGVVPQPLEEILLHTWPYPSLLIAGNYKKLYNFIDENAGDCLRLGQEEFRLTRDEAIQNLLFVLGFNAYGGFSVFLPSLIGRITGDNSGLQERIRTEVRRVCGSGSDLNFKTVNEMELVKSVVYETLRFNPPVPLQFARARKDFQISSHDAVFEVKKGELLCGYQPLVMRDANVFDEPEEFKPDRYVGETGSELLNYLYWSNGPQTGTPSASNKQCAAKDIVTLTASLLVADLFLRYDTITGDSGSIKAVVKAK
What is the function of this protein?
Catalyzes the conversion of (9Z,11E,15Z)-(13S)-hydroperoxyoctadeca-9,11,15-trienoate to (9Z)-12-oxo-dodec-9-enoate and cis-3-hexenal.  Possesses low activity toward (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate (PubMed:9701595, PubMed:16258015).  Required for the synthesis of the green leaf volatiles (GLVs) hexanal and trans-2-hexenal (PubMed:16258015).
What are the official names of this protein?
Linolenate hydroperoxide lyase, chloroplastic, Cytochrome P450 74B2, Hydroperoxide lyase 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ECM8_YEAST
Sequence: MDYGYFFPAQRIEETNGVDFWIDSNAEFTQSKRPDSSTSTLSRVLTDTTNVSNNSGSLKRKTIKNKIFPQRKIFNDSENFDFGKANTDCKHVFKSISKQLIFLPRCFQHHSIRGWMKDRYSEFGYKIKRNQNCPPSACVQALYNTSRSNTEESNPNSLDSLIMYKYMRYSEKKKELMCRFCQGNNWILAENYLKHLFFAHGILSEFKPHTLYHFESKLLKIQGKLNFKIQVLKEPEFSKKILNSLTVSIIPSPLAYYTQTLNGGFRRIHVKCPHCENWIRLGWCEYDEIIRDSFQDFESLRNLNADYNGMSYIQTRNREDIEGIYENYFTHYIQCDLATFRTKCLYVQVITKSN
What is the function of this protein?
May be involved in cell wall organization and biogenesis.
What are the official names of this protein?
Protein ECM8, Extracellular mutant protein 8.
Protein: CAPP_ECO7I
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGHEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.