PharMolix/UniProtQA huggingface dataset:
Protein: PRGC1_HUMAN
Sequence: MAWDMCNQDSESVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPSNIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHNHRIRTNPAIVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCTSKKKSHTQSQSQHLQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSESSGTQGNNSTKKGPEQSELYAQLSKSSVLTGGHEERKTKRPSLRLFGDHDYCQSINSKTEILINISQELQDSRQLENKDVSSDWQGQICSSTDSDQCYLRETLEASKQVSPCSTRKQLQDQEIRAELNKHFGHPSQAVFDDEADKTGELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLSYPWDGTQSYSLFNVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors (PubMed:10713165, PubMed:20005308, PubMed:21376232).  Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter (PubMed:10713165, PubMed:20005308, PubMed:21376232).  Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis (PubMed:10713165, PubMed:20005308, PubMed:21376232).  Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism (PubMed:10713165, PubMed:20005308, PubMed:21376232).  Acts as a key regulator of gluconeogenesis: stimulates hepatic gluconeogenesis by increasing the expression of gluconeogenic enzymes, and acting together with FOXO1 to promote the fasting gluconeogenic program (PubMed:16753578, PubMed:23142079).  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner (PubMed:23836911).  Also involved in the integration of the circadian rhythms and energy metabolism (By similarity).  Required for oscillatory expression of clock genes, such as BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Nucleus, PML body. SUBCELLULAR LOCATION: [Isoform B4]: Nucleus. SUBCELLULAR LOCATION: [Isoform B4-8a]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform B5]: Nucleus. Nucleus, PML body. SUBCELLULAR LOCATION: [Isoform 9]: Nucleus.
Protein: MKNK1_MOUSE
Sequence: MVSSQKLEKPIEMGSSEPLPIVDSDKRRKKKRKTRATDSLPGKFEDVYQLTSELLGEGAYAKVQGAVNLQSGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNRNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKRKHFNEREASRVVRDVATALDFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFRDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRMCQNKLFESIQEGKYEFPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEQEALAEGLCSMKLSPPSKSRLARRRALAQAGRSRDANPCLTPAGL
What is the function of this protein?
May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: RPIA_BURO0
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESLQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: KHSE_BRUA4
Sequence: MAVYTDINEIELGAFLQQYDIGTLTSYKGIAEGVENSNYLLHTTSGSFILTLYEKRTNREDLPFFLGLMQHLASRGLECPQPVVRRDGTTIGELAGRPAAIVTFLEGMWMRRPTVEHCEAVGEGLAHMHLAGADFSLRRRNGLTLADWRPLWNLSRGRADTVEPGLVREAEADLAFLEKNWPADLPQGVIHADLFPDNVFFLGDRLSGFIDFYFACTDTLAYDVAVCLNAWCFEKDFSYNRTKGAALLRGYTSVRPLSAAEADALPVLARGAAIRFMLTRLYDWLNVPEGSFVVKKDPMEYVRKIRFHRQIETAAEYGLEQQGAAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RL13_DROME
Sequence: MGKGNNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPASGALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANFAKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGESSLEECKLATQLKGPVLPIKNEQPAVVEFREVTKDEKKFKAFATLRKARTDARLVGIRAKRAKEAAESEDAAKGDPKKAKK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).  As part of the LSU, it is probably required for its formation and the maturation of rRNAs (Probable).
What are the official names of this protein?
60S ribosomal protein L13, BBC1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI31_HUMAN
Sequence: MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFKCPLCKTSVRKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEHEKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLKTKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQLQADRKKDENRFFKSMNKNDMKSWGLLQKNNHKMNKTSEPGSSSAGGRTTSGPPNHHSSAPSHSLFRASSAGKVTFPVCLLASYDEISGQGASSQDTKTFDVALSEELHAALSEWLTAIRAWFCEVPSS
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a regulator of antiviral immune response and inflammation by mediating ubiquitination of substrates (PubMed:18773414, PubMed:27929086, PubMed:27992402).  Acts as a regulator of innate immune defense against viruses by mediating 'Lys-63'-linked ubiquitination of MAVS, promoting MAVS polymerization and formation of three-stranded helical filaments on mitochondria (PubMed:27992402).  Acts as a negative regulator of the NLRP3 inflammasome by catalyzing 'Lys-48'-linked ubiquitination of NLRP3, leading to its degradation (PubMed:27929086).  Regulator of Src-induced anchorage independent cell growth (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM31, Tripartite motif-containing protein 31.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
Protein: RS7_METCA
Sequence: MSRRRRSERREVIADPRFGSETLARFVNMLMVSGKKSIAEKIVYGALDHIEAKTSQNSLEVLNKALENVQPVVEVKSRRVGGATYQVPIEVRPARRMALGMRWLIDAARKRGEKGMVMKLAAEVLDAKESRGSAVKKREDTHRMAEANKAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CLD23_MOUSE
Sequence: MRTPVVMTLGMVLTPCGLLLNLVSTLAPGWRLVKGFLDQPVDVVLYQGLWDICREQSSRERECGQPDEWNYFQTQPVQVARGLMITSLATTALGLLLASLGVRCWQDEPHYGLAGLSGVVFFVAGLFSLIPVSWYNHFLSDPDVLAAPSSPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCEERCRRCRKAPPAGPRRSSISTVYVDWPEPALTPAIKYYSDGQHRPPPTAEHRDTSKLKVGFPMPRPPPKSYTNPMDVLEGEEKKTATSQGGSSSRSTRPCQNSLPCDSDL
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-23.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: AZO1_STAAW
Sequence: MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPLNQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDYFKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLNDSEFQLRARLFVDQIVSFVNNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: HRCA_NOVAD
Sequence: MTAPTLTDLTDRAREIFRLVVEGYIASGHPVGSKALAGHGSVNLSPASIRSVLQELQDAGLLAAPHTSAGRMPTEFGLRLFVDGIMQVAEPSAAERAQIERGLVAGGTIESALAAASTALSELSAGAAVVMVPKREPRLVQISFVPLSPLRALAVLVSEDGGIENRVIDLPEPVGPSALEQAGNYLTSRLHGRTLGEAAGVVRAEIAGGRSALDEASADLVQRGLVVWTQDATARPVMVVRGQANLLDETALQDIERVRQLLEELEGAEAIARVLDAAREAQATRIFIGSENRLFSLSGSSVIASPWRDGDGRVVGVVGVIGPTRLNYARVVPMVDFTAQTLGKFIGQDGFSRK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YIG7_YEAST
Sequence: MGVHFDDNANTTWEATDPGVSSDCDGQHRVTESIQLQNFSNTDMESMLDEEGRENSKSKWLLLKRKHPIQKFIERVWNGPVEPSDEPPSFPKRWGWLKKIDDFPQTTFKTKIPSKLIRLLLLIVYCCFWMRIFYSLIYPYLIKPPYFHPNDGSEKIPILSLSCNSYLNWEGTNNECGLNAKNCGPLDNKEYMIRCPALCDRGGWTYSAIAVGNRRVKYTGYEIGGGALFSEEDPMVVSYPYRSDSFPCASAVHAGVISPFYGGCTKVSMQGAQNSFPSKKGMYNTGFSVAFNSFFPGSYSFRDIQGGILSGCYDPRAAVVALNMLFGLPIFYLYDSIYGYWINTIVGYWTLVLSLDPPLLTDAHDPASVYELFSVGFQRLLPLCFVLYVVWKSAVKRTLENGSPIAKVILWYPTFWLGISNNVTFDRLPVDRLTTTDLKEQAGALTAVGSIAATILTCAVIQAYSLWKSGRFKKYFKIYICFIGGLIALGSLPGLNLRIHHYILGSILVPGCATRGSSAYLFQGILVGLILSGVARWDFASIVETDTALLRGEAGASLKPPILDFNDDQNHSLSWHLNATDPVIDQIGNIDGFSLLLNDVEVYVGKNETVSIDVLRMENPALAQMMDDALDASNGTIDLYLRVARASVRSPTNRGDYTNAGVLQWPNGMWQKPEPGVS
What are the official names of this protein?
Uncharacterized protein YIL067C.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: NRPS9_ASPFU
Sequence: MPRSTPVASEQVDFVMKLLGNTTKQITTATYIKLAWAVVISCNTGSNDTVFGITVNGRGAPIDGAGEMTGATIATIPQHGCILRVWSLPRMPAGMISRERVQRLLQHLELVLQDLMADPSCKVGDLPRMSRQEWDQIQRWSGTLPPVSRQCVHEIVNQRSLQFPNACAVSAPDGDLSYAELIRSANAVAAELLVHGVERGNYIPVLFEKCKWSPVAMLGVLKAGAAFVLLDSSYPPQRLHTICGGLKTQIILCSKDMYARAASLGPTAIAIHENAAFLADIPDVTFPVVSPENAAYVVFTSGSTGTPKGAVIDHQSYCSGALAHNRAHVLGRNSRVLQYASYAFDVSIMETLSTLMAGGCVCILSDLERHDHFANSVQRLAVTHAFLTPSTARLLMQRELPSLCVLVLGGEAMSLADRSYWMSRVRLMNEYGIAECSVASTIREVSHVEQKDIGFPMGVVAWVVDQNDHEKLVAIGATGELLLEGPSPPVGRSSSNRAGSGRCAMGSQAGSYKTGDLVRYNEDGSLSFISRKDSQIKIRGQRFELEEVEQHLRRIDEIQEATTVVAAPSDRPKQPYLVAFIVPRARESFCVCSARALIPHPTEEFRLQAATIQTKLHSILPAHMVPAIYLPVNRMPKTSSDKIDRCRLKEEVGKWSWSDLRAYSVSSMSHRAPSNRVEQDLQRVWEQILGILLDSVGVEDSFFHLGGDSIIAMQVVAEARSRGLDHSVQDINQLKTIKAIANKIGDVQRAAIKLVQNHAMLRARYVRQKDGAWKQFFTGYTEQCFRFSVHQVKSAQEMRQIIGESQTSLNPEHGPVFTVDLFHHGGEQSLLMIGHHLVLDLVSWRIILADMEAMILDPQHQPHLTMSFQTWAHLQAEYGTRHLEPPPGQQPCSIDEPSMRQFWGAENNANTGGDSKTRLIRMNDDLTRKLFGPSSQALDVEPVELLHAAILFSFVNTFPQRPALVIFGEAHGRETWDSSVDVTRTIGWFTTLWPVVAQVNPSDSLETVARTVRQARRAMDMHGWTHFTSVYHNTRQTKRSAGAHLMEITFNYAGKFQQVEQDGSLFRMEPMAKQNLFDGAAELGRWAMLEINSVILNGLLEFHVPYNRGTDEARVLTPWMDNLVKCLEGLASGFA
What is the function of this protein?
Nonribosomal peptide synthesis (NRPS) is a key mechanism responsible for the biosynthesis of bioactive metabolites which are potentially contributing to organismal virulence.
What are the official names of this protein?
Nonribosomal peptide synthetase 9.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: CCME_EHRRG
Sequence: MKRKYRRLFVVIITLSIFAGSVVFVLGKLKNNVSFFYTPTELLSSSLINRPNIRIGGMVVKGTVQKYDDSIVFHITDLKNYIKVVYKGILPPLFSEGSWIVAKGKMVNGKFIASEILAKHDENYMPNKYKTNNL
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SYR_BUCAP
Sequence: MNIKYLIKKDIEQALIKINSNYTYEVFIISSKKIELGHYQVDNLMKISSRLKIKPYKLFQKILILIEKKKIYKKIIFSHPGFINIFIKNEWLSEKLEIPFISSRLGVKYIYPKKNIVIDYSSPNIAKEMHVGHLRSTIIGDVTVRILEFLGQKVIRANHIGDWGTQFGILIAYLEDKKLLKKLKKNLLSLQDLDNIYCQSKKQYNSNELFSKKSREFVVKLQNGDQYCCAIWKKLVSITMLENYKIYKKLNVTLEEKHTMGESFYNPMLPKIVEDLKKQKIAIEKNGAVIVFLDEFKNRMGDSMGVIIRKKDKGFLYSTTDIACLKYRYQNLHADRIIYYTDSRQYQHLLQSWTIAEKANYISKNLLLEHHMFGMMLSKNRRPFKTRDGNTIKLSNLLNESINRATNLIQKKQPNLCKKKLIKLGEIIGISAVKYSDLSKNRNTNYIFDWDKMLSFEGNTAPYIQYAYTRIISILKKSNIPLHKIKMKIILNEESEINLAIKILEFEEIILLIAKNGTPHIMCKYLYQLSTYFSHFYENCSILFSEKIKIRKSRIKLSFLTAKTIKKGLNLLGIKTIKKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ECOUT
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MURA_AGRVS
Sequence: MDRIRIVGGNALNGIIPISGAKNAALPLMIASLLTSDTLTLENVPHLADVELLLRILGNHGVDIAVNGRRERQSGSYSRTIHFTCRTIVDTNAPYELVSKMRASFWVIGPLLAREGKARVSLPGGCAIGTRPVDLFIDGLRALGATLEIDSGYIEATAPKGGLIGASYTFPKVSVGATHVMLMAASLARGTTVIHNAAREPEVVDLANCLNAMGAKITGQGTATITIEGVTSLSGARHRVLPDRIETGTYAMAVAMTGGDVTLEGTDITLLDTAVEALRRAGAEVSAIEDGIRVIGHGDAIRPVDIVTEPFPGFPTDLQAQFMGLMTRAQGVAHVTETIFENRFMHVQELARLGAKITLSGQTARIEGVQRLRGAPVMATDLRASVSLVIAGLAAEGETLVNRVYHLDRGFERLEEKLTRCGAIVERISD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPC3_YEAST
Sequence: MPAYHSTFPVDPNTDRMVGNFALLPLNTKFRGPAYPSNSDYDIIDECLDLFRANSFFKNFEIKSPADRVLIYGILFINDCLAHLKITTSFNEAVKVLTNVALDNFTLPGTPGFPLNNVYQVPVQDHNSMDLLKTYIQQFRQELAMRLLERVYSSTDSKEYPSKFWLAFTRRRFMNKSL
What is the function of this protein?
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 3, Arp2/3 complex 21 kDa subunit, p21-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MRAY_PARPJ
Sequence: MLLALAQWLQNDASFLRVFSYLTFRAVMATITALLIGLVCGPAVIRKLTAMKVGQAVRKDGPQTHLVKSGTPTMGGVLILLGIAVATLLWADLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEASNVRVFDLFMAWVRSGLSMGLPPHADLMLPFVKSISYPLGVWGFIVLTYLVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSSVYSKYLLFPHIAGAGELLIFCSAMGGAGLAFLWFNTHPAQMFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKFTKRRFGEGRRLFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFG_CAMJR
Sequence: MSRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERGITITSAATTCFWKDHQINLIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPVPLQIPIGAEDNFKGVIDLVTMKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEEIKTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSVKSTDDGEFAGLAFKIMTDPFVGQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSNKREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERMDFPDPVISVAVEPKTKADQEKMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVAYRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAVDKGVQEALQNGVLAGYPVEDVKVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVILEPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKIITAFCPLAEMFGYSTDLRSQTQGRATYSMEFDHYDEVPKNVADEIIKKRNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPH2_MACLB
Sequence: MVLIRVLANLLVLQLSYAQKSSELVIGGDECNINEHPFPVALHTARSKRFYCAGTLINQEWVLTAARCDRKNIRIILGVHSKNVPNEDQQIRVPKEKFFCLSSKTYTRWDKDIMLIRLKKPVNDSTHIVPLSLPSSPPSVGSVCRIMGWGTITTTKVTYPDVPHCANINMFDYSVCRKVYRKLPEKSRTLCAGILQGGIDSCKVDNGGPLICNGQIQGIVSWGGHPCAQPHKPALYTNVFDYTDWIQSIIAGNITATCPP
What is the function of this protein?
Snake venom serine protease homolog that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease homolog 2, Venom serine proteinase-like protein 2, VLP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_PSEPK
Sequence: MSWFTPEVIDVILTVLRAIVVLLAVVVCGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWNPPFVDRVIFTLAPVVAMSALLIAFVVIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKYALLGSLRASAQTVSYEVFLGLALMGVVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIILISALLVTLFFGGWHGPFGILPQLSFLWFALKTAFFIMLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLVTAAIVLYNTPAVAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y340_BORBU
Sequence: MYDLPLIDNLPVIKRARFFYLYDIHGKRYLDLYLNGGRNFLGYRVQGLNRLFKQTMSRGLISPYPSVFKNQFINLVFTFFKEAGSVYIFKLEKDAKEFLLSLTGKNKFFMPWEKEEGIYEFRVGFSNIKYPMIFNIPLPDFMSVSIVVMDNLSRKIEFKDNFDAVTLSLARHTLSKLLFYKKNIDIDFNSFATPLFRIADRYMLPLYDACYHAEIFNEFLKFGYLISPNFSIPSIVPLKFSKGDLDNFKKLCFALKNKFIDGLDSDPYK
What are the official names of this protein?
Uncharacterized protein BB_0340.
What is the protein family that this protein belongs to?
To T.pallidum TP0678.
Protein: DXR_SHEB9
Sequence: MQNMVILGATGSIGASTLSVISANPFAYSVYGLVANASVDKMLALCVAHKPKVAHMVDEAAAKQLRAVLPATLNIQVTTGMNDLLGLVTAAEVDTVMAAIVGAAGLVPTLEAVKAGKRVLLANKEALVMSGELFIEATKRSGAVLLPVDSEHNAIFQCLPQEVQANLGRCDLAASGISHILLTGSGGPFLRSDLATLAAMTPAQACKHPNWSMGPKISVDSATMMNKGLEFIEARWLFNTQAEQLKVVIHPQSVIHSMVQYRDGSVIAQMGNPDMRTPIAHCMAYPQRIHSGVEPLDFFKVGQLSFYEPDFERFPCLALAMEACAQGQEATTVLNAANEIAVEAFLQGQIGFTQIAKVNEACLVTVPKRPMGSIEDILALDAQTRVYARETLASIA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: DUT_CITK8
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEEFEATDRGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: KDUI2_BACTN
Sequence: MSASAQVNYKMQVACNPQDVKTYNTNRLRSSFLMEKVMVPDQINVTYSMYDRLIFGGAVPATKELVLETIDPLKAKYFLERRELGVINIGGEGIVTVDGKEYTLNFKDALYVGRGKQKVTFKSKDASKPAKFYINSATAHKEYKTQLITIDGRKGSLKANSFAAGKMEESNDRVINQLIVNNVLEEGPCQLQMGLTELKPGSVWNTMPAHTHSRRVEAYFYFNVPEGNSICHFMGEPQEERIVWMQNEQAIMSPEWSIHAAAGTSNYMFIWGMAGENLDYGDMDKIKYTEMR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 2, 5-keto-4-deoxyuronate isomerase 2, DKI isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the KduI family.