PharMolix/UniProtQA huggingface dataset:
Protein: BIM1_YEAST
Sequence: MSAGIGESRTELLTWLNGLLNLNYKKIEECGTGAAYCQIMDSIYGDLPMNRVKFNATAEYEFQTNYKILQSCFSRHGIEKTVYVDKLIRCKFQDNLEFLQWLKKHWIRHKDESVYDPDARRKYRPIITNNSATKPRTVSNPTTAKRSSSTGTGSAMSGGLATRHSSLGINGSRKTSVTQGQLVAIQAELTKSQETIGSLNEEIEQYKGTVSTLEIEREFYFNKLRDIEILVHTTQDLINEGVYKFNDETITGHGNGNGGALLRFVKKVESILYATAEGFEMNDGEDELNDKNLGEHGTVPNQGGYANSNGEVNGNEGSNHDVIMQNDEGEVGVSNNLIIDEETF
What is the function of this protein?
Binds microtubules.
What are the official names of this protein?
Protein BIM1.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RLMN_CHESB
Sequence: MTLTIDTSTPESRALLRPDPTVEKKPLIGLSREEMAQALASIGVPERQVNMRVRQLWHWLYVRGVSDFSRMFNISKELRAKLDEHFTIARPEIVEEQISQDGTRKWLLRFPPRGAGRPVEVETVYIPEEDRGTLCISSQVGCTLTCSFCHTGTQKMVRNLTAGEILDQLLIARDRLGDFPDADTPDGAIVPAEGRKITNIVMMGMGEPLYNFENVKQALLVASDGDGLSLSKRRITLSTSGVVPEIYRTGEEIGIMLAISLHAVRDELRNELVPINKKYPLKDLLDACRAYPGLSNARRITFEYVMLKGVNDSLDDARELVRLLKGIPAKINLIPFNPWPGSAYECSDWEQIEKFAELVNRAGYASPIRTPRGRDILAACGQLKSASERMKKTERLKLEAMMIAGHGD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNC_CALSA
Sequence: MAIMQINFYSKMLKKNTTILAILPVDKPDKKFQKDVDSENLKTLYLLHGYAGNYMDWLCGARIVELSMRYNVAVFLPSGENSFYLDDEEKEEYFGEFVGNEIIEFTRSVFPIPQKREKTFIGGLSMGGYGALRNGLKYNKNFVGIIALSSALIIHKIAGIPKDYRNAYASYNYYRRVFGDLNSLIGSDKDINALVTKLKQEKGSIPKIYMACGRDDFLVQENRDLFNFLKNEGIDVVYEEDEGGHDWDFWNKYIANAFEWMSKVSD
What are the official names of this protein?
Acetyl esterase, Acetylxylosidase.
Protein: MTC2_YEAS1
Sequence: MGDHNLPDFQTCLKFSVTAKKSFLCMYRDSVSKEKLASSMPSTCDIQLKRAINDAYPGGGIKVTVLNSTTASLDSLATTHVKEFEIVIIPDINSLLQPDQAKLVKIMRDCTVAIEKAQSTRIFIGVVHWNNPVQPSGAAKDGDEAGKPAPKTRIFLPTSLRMGAWLKHKFWFACAPPYLDFESSTESSINTRANNSIGMAEEEKQEPESKRSIILNEEANLNDVFVGSTVRRYILDIMVHLRTHRLTYNAKAGGVYTNSLDDVVLLSRLIGLHSGKMFVSPSHVKEASRWYFPMHLELVQRSSMDSSLLYGSDPNLVDEMLEKLAKIKCEEVNEFENPLFLESLVVKNVLSKVVPPV
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 2.
What is the protein family that this protein belongs to?
Belongs to the MTC2 family.
Protein: PYRDB_STACT
Sequence: MSRLNVELPGLDLKNPVMPASGCFAFGAEFSQFYDLSELGAIMIKAATKEARYGNETPRVAETDSGMINAIGLQNPGVHHIIEHELKKLEQFDVPIIANVAGSVEEDYVYVAEHISKAPNVKALELNISCPNVKEGGMQFGVDPQVAAELTRKVKAVSEVPVYVKLSPNVTNIVEMAKAIAEYADGLTMINTLVGLRIDGKSGKPIIANTIGGLSGPAIKPVALRMVYEVRKAIDIPIIAMGGVQNAQDVIDYISVGANAVAVGTANFQNPMVCKEIIDELPTLLDKLGVDHINELYGRTHEVMK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_ECOLC
Sequence: MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPHTLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGAVDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPRSAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADTAVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVNADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISETEKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKYDTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQMRDPATGQAHTAHTNLPVPLIYVGDKNVKAVAGGKLSDIAPTMLSLMGMEIPQEMTGKPLFIVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: IGFL3_HUMAN
Sequence: MRPRCCILALVCWITVFLLQCSKGTTDAPVGSGLWLCQPTPRCGNKIYNPSEQCCYDDAILSLKETRRCGSTCTFWPCFELCCPESFGPQQKFLVKLRVLGMKSQCHLSPISRSCTRNRRHVLYP
What is the function of this protein?
Potential ligand of the IGFLR1 cell membrane receptor.
What are the official names of this protein?
Insulin growth factor-like family member 3.
What is the protein family that this protein belongs to?
Belongs to the IGFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS_CORJK
Sequence: MTNSSATSNPQPSDVEIAQAHTLEPITTIAERAGIPEAALIPYGRTKAKIDVPALRAEREGVNKKGKLVLVTAMSPTPAGEGKSTVLIGLADAVRTAGRQTMVAIREPSQGPVMGIKGGAAGGGYAQIVPMEDINLHFTGDMHAITAATNTLAAMVDNHVQHGNALGIDPRRVTWRRCLDVNDRSLRHVVTGLGGPGQGTPREGGFDITAASEIMAILCLATDLEDLKKRIGRIVVGQTYDRRPVTAGDLKCAGAITALLRDAINPNLVQTLGGTPALVHGGPFANIAHGCNSLIATTTALDLSEVVLTEAGFGSDLGAEKFFDIKSRAGDLDVAATVVVATIRSLKHNGDSVLKAGLANLERHVSNIRKFGVEPVVALNLFSSDTAAERSMVADWGEQFGVRVVECSVWAEGGAGAADLATAVLEVVDGVSDEDASSSSHQIYQPVDGVEATLHTLATEIYGAADVQFGPQALKDLAFLKDNGWDKLPVCVSKTQYSFSDDPSALGAPSGHTLHVRELVPRIGAGFVVALTGDVMTLPGLPKKPAAERIDVNAQGVISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: UREG_BURL3
Sequence: MNAPAPSSARRTKKLPPLRVGIGGPVGSGKTTLLEMLCKAMRDRYDLVAITNDIYTKEDQRLLTVAGALPEERIMGVETGGCPHTAIREDASINLEAVDRMLSRFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPLVGANLDVMASDTKKMRGERPYVMTNLKALEGVADVIAFIEKKGLLTV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_AZOC5
Sequence: MPKLNDVVAEIAADLAKATERGAVATYIPMLAEVPINQFGMAVVTADGETILAGDADTVFSIQSISKVFTLTLALGQIGDALWTRVGKEPSGNAFNSIVQLEYEHGIPRNPFINAGAIVVADAMLSGHQPREALGAILRFVRFVAADESITIDEAVARSEKETGFRNTALANYMRSFGVLRHPVDHALGVYFHQCAIAMSCRHLARAGRYLAFSGRLTPEGPSVVASERARRIAALMLTCGHYDGSGDFAFRVGLPGKSGVGGGILAIAPGKASIAVWSPGLDPHGNSLLGSIALERLAKAMRWSVFAG
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: GLGC_STRCO
Sequence: MLGIVLAGGEGKRLMPLTADRAKPAVTFGGTYRLVDFVLSNLVNGDILRICVLTQYKSHSLDRHITTTWRMSSLLGNYVTPVPAQQRLGPRWFLGSADAILQSLNLVHDEQPEYVAVFGADHVYRMDPRQMLAQHIESGAGVTVAGIRVPRAESPSFGVITPGSDGQTVTGFLEKPADPPGLADDPGCVFASMGNYVFTTKALVEALHRDAEDPDSVHDMGGSILPQLTDRGEAALYDFSANHVPGETTRDQGYWRDVGTLDAYYDAHMDLIAERPAFNLYNRDWPVYTHSTQLSPARFNAGGIASESIISAGCLIRGQVTRSVLSPGVVVDPGAVVQGSVLHDNVHIGRGAVVRGAVLDKNVQVPPGATIGVNPQRDGELYTVSKGGVIALGKGQRVP
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SSRP_PERMH
Sequence: MGIKVVATNKVAYHNYNIIETYEAGIVLKGSEVKSIREGSVNLRDSFVRIDNGEAFIYNMYIAPYKPASKLQHDPYRKRKLLLHKREILKLMGKVQEKGLTIIPTKVYLKNGKVKIEIALAKGKAKYEKREAIKERDMKRELSKKYKGKIKL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CP120_SYNY3
Sequence: MITSPTNLNSLPIPPGDFGLPWLGETLNFLNDGDFGKKRQQQFGPIFKTRLFGKNVIFISGALANRFLFTKEQETFQATWPLSTRILLGPNALATQMGEIHRSRRKILYQAFLPRTLDSYLPKMDGIVQGYLEQWGKANEVIWYPQLRRMTFDVAATLFMGEKVSQNPQLFPWFETYIQGLFSLPIPLPNTLFGKSQRARALLLAELEKIIKARQQQPPSEEDALGILLAARDDNNQPLSLPELKDQILLLLFAGHETLTSALSSFCLLLGQHSDIRERVRQEQNKLQLSQELTAETLKKMPYLDQVLQEVLRLIPPVGGGFRELIQDCQFQGFHFPKGWLVSYQISQTHADPDLYPDPEKFDPERFTPDGSATHNPPFAHVPFGGGLRECLGKEFARLEMKLFATRLIQQFDWTLLPGQNLELVVTPSPRPKDNLRVKLHSLM
What are the official names of this protein?
Putative cytochrome P450 120.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS19_RHORT
Sequence: MARSVWKGPFIDGYLLNKAEKARSSGRNEVIKIWSRRSTIMPQFVGLTFGVYNGQKFVPVLVTEQMVGHKFGEFAPTRTYYGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ARLY_BACMK
Sequence: MSKLWGGRFTEEAEAWVEEFGASISFDKQLVSQDIKGSIAHVTMLAKQGIVTKEEAEKIKIGLQYLLEEAKQNKLNFSVEAEDIHLNIEKMLIERIGEVGGKLHTGRSRNDQVATDMHLYLKEKVEDIIKATKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALAGTTFPIDREYSAELLGFNGIYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQEFQFIEMSDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTVEGCLHIMAGMIETMTVNKEKMGQAVTQDFSNATEIADYLASKGLPFRQAHEIVGKLVLHCTQKGIYLLDVPLETYKEMSPLFEEDLYEVLSPYAAVKRRNSAGGTGFEQIEKALEKAKGLAIEFVGI
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD91_HUMAN
Sequence: MDDDDFGGFEAAETFDGGSGETQTTSPAIPWAAFPAVSGVHLSPSSPEIVLDRDHSSSIGCLSSDAIISSPENTHAANSIVSQTIPKAQIQQSTHTHLDISLFPLGLTDEKSNGTIALVDDSEDPGANVSNIQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSALIATEPVDIE
What is the function of this protein?
Involved in the regulation of membrane traffic through the trans-Golgi network (TGN).  Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes.
What are the official names of this protein?
Coiled-coil domain-containing protein 91, GGA-binding partner, p56 accessory protein.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network. Note=Colocalizes with GGA1, GGA2 and GGA3.
Protein: LONF2_HUMAN
Sequence: MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAVGLRDRPLSAENPGGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDASAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRRILVIITRKMNSRQELANARERNN
What are the official names of this protein?
LON peptidase N-terminal domain and RING finger protein 2, Neuroblastoma apoptosis-related protease, RING finger protein 192.
Protein: NHAA_SHEPA
Sequence: MERAIRNFLSQESAGGILLMVSVVLAMILANSPLSGMYHGFLETEMQVRVGNLDIDKTLIHWINDGLMAIFFMLIGLEVKRELLEGALSSRAQASLPTFAAIGGMVFPAAVYLIFNYSDPITQVGWAIPAATDIAFALGIMALLGSRVPVALKVFLLALAIIDDLGVVVIIALFYSTDLSTISLIIAAAAILGLIGLNRKGVTSLAPYGVVGLILWIAVLKSGVHATLAGVIIAFCIPLRAKDGSSPSESLEHSLHPWSTFIILPIFAFANAGVDLSGMSLSSLLSPVPLGIALGLLVGKPLGIMLFSYIAVKLKLAVLPEGMGWRHITPVAVMCGIGFTMSMFISSLAFVGEGQMYGDYARLGILLGSIASATIGYFWLSKVLPEKGAKA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TKTI1_HUMAN
Sequence: MQTLRQEAARPCIPSGTLEASFPAPLYSDDYLSLEGSRWPPAIRQATRWKYTPMGRDAAGQLWYTGLTNSDAWEAWYNLPRAPASPFREAYNRWHSCYQHRECSMPSAYTQHLRETAWHDPIVPAQYQAPSTRWGSALWKDRPIRGKEYVLNRNRYGVEPLWRASDYVPSLSAPQRPPGTTQNYREWVLEPYCPSTCQRSPPSLTPTPR
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.  Located at the center of the tektin bundle where may function to recruit tektins or stabilize the bundle.
What are the official names of this protein?
Tektin bundle-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RBFA_MAGMM
Sequence: MTIRTERVGNAIRKEVASMLTRGEIKDPRLGGFVNIQEVRVSPDLSYAKVYYTVFGESDQAGVADAWQRASGFLRNVIAKRLKLRHAPELRFELDHVADYSKRIDELLNGLEIPPADDSDETH
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJC_VIBCM
Sequence: MKVIFNADDFGLTQGVNQGIVKAHLDGVVKSTTLMVGMPAEQHAVQLAKQLPDLKIGLHLRFTAGRPLTGERNLTDEHGVFTAYRDFWQRRDYQPEAIYHEAIAQVEHFLKLGLTLSHLDSHHHAHTHPQLAPIIYEVAKKYHVPLRDIGMAGEEAFGCRYHFTDFFYDQRLGIDPLMKHLLELKERFDLVEVMCHPAFVDPLLEKCSGYAKQREEELHILTSAQLIQLLVAHDIEITDYSALISAPLHSCV
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: PKN3_MOUSE
Sequence: MEHRKPGTGQRAPKDEKEMVRRAIQKELKIKEGMENMRRVATDRRHLGHVQQLLRASNRRLEQLHGELRELHAQVLLPASAEPVTSEPQPRAEQSRARLSEALHRQLQVELKVKQGAENMIHTCASGTPKERKLLAAAQQMLKDSQLKVALLRMKISSLESSGSPEPGPDLLAEELQHRLRVEAAVAAGAKNVVKLLGGQRMQDRKALAEAQAQLQESSQKLDLLRLALELLLERLPPTHSLRSRVTQELWMAMLGNPQPLGTLVKPIALTGTLQVRLLGCKDLLVAVPGRSPMAVLAGSPSESWLRTRSRQQRGGGELASEVLAVLKVDNRVVGQTGWGLVAEKSWDQSFIISLDRARELEIGVHWRDWRQLCGVAFLKLEDFLDNACHQLSLSLVPQGRLFAQVTFCEPVIERRPRLQRQRCIFSKRRGRDFMRASQMNLSMAAWGRLVMSLLPPCSSPNTASPPKGRPSTAVCGTPSAASPSNFLPMKTLSKEDTKPPPKPPRLYLQEPAPGTPCTKRPHMDPRPAVVPALAALSTRKPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILETVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHEDVFPEPQACFYLACVVLGLQFLHEKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQGLELIQKLLQKSPEKRLGAGERDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVSQSSLTARQQAAFRDFDFVSEQFLES
What is the function of this protein?
Contributes to invasiveness in malignant prostate cancer.
What are the official names of this protein?
Serine/threonine-protein kinase N3, Protein kinase PKN-beta, Protein-kinase C-related kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear and perinuclear Golgi region.
Protein: F16PA_VIBC1
Sequence: MSGLRTLGEFIVEKQADFPHASGDLSSLLASIRLAAKIVNREINAAGLGDITGAVGTENVQGEDQQKLDVYANDKFKAALEARDQVCGVASEEEDEAVAFNKELNQNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVSPIGTPPTEEDFLQPGHKQVAAGYVIYGSSTMLVYTTGNGVNGFTYDPSIGSFCLSHENMMIPEDGKIYSINEGNYIRFPQGVKKYIKYCQENVPEDGRPYTSRYIGSLVADFHRNLLKGGIYLYPSTQSHPQGKLRLLYECNPMAFLIEQAGGLASDGVNRIMDLKPTELHQRVPFFVGSKNMVNKVEEFLELNREED
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP2_BIFLO
Sequence: MSNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDPKKDIWLYINSPGGSITAGMAIYDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTSHARVLMHQPSGGIGGTATDVRINAELIMDMKKTMSELTAEQTGHTLEEIYRDNEYDHWFTAQEALDYGFVDKLVTTPDTIGNNQQGE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1409_METJA
Sequence: METMKAKELAQKILLDIYRNLDEFSKDIIRGDLADIEFKGFYLKGKNGEKAYIRNLDDFENLKDFDVEMRKYKLKSINLKNLDEGLMIINLSSRVSKEYKFEANEYSIIYPSNNTTIEFKERVLKWMELEDDELDEKIIEFDTKMNEILEELLEDVEVEEEISVYIDVFMDVNKIENFVEKDDERIIIWIHPVFLFSNDDVLRGLLAYELSRFKSRFLEVGYKDIIKYCRELKKLTNKKPKVLEKIKDIANKYGDIDSLNLINEIENE
What are the official names of this protein?
Uncharacterized protein MJ1409.
Protein: TPEC_TALSN
Sequence: MSHTFHCPQPLLVMIALTIFRYATLAIALIVGFVILKAIYNVFFHPLRNFPGPLRYRASRIFWVLDLIEGRQIYTIDQFHKRYGPVVRTAPDELSFTIPEAWRDIYGHRVGLVSGLPEIPKWPLFYKFTKQDVSIFNAPQGQHGTLRRALAHGFSEKSTRAQESIIGGYVDLLVTRLKEVADSKAPANMVQWYNYTTFDIVGDLVFGNSFHCLDNANYHPWVSLFADSTRQNSIFVGLKILGLDFLALATMPLVIRNMIKHFNLTKEWLRERRKLGTDRGDLIEGLLKKEGEGINFDEIHGTSMGLIFAGSETTATLLSGVTYLLLQNPKTLAKVTMEVRSSFKSDKEITLLSVQNLDYMLACLDEAFRLYPPVGIGLPRQIPKGGVKIAGIYVPEGSIVDVPQYAIHRSPDHWTEPESFHPERFLGDSRFASDKVETLQPFAVGPRNCIGRNLAYAEMRLILARVLYNFDLKMDPSCSGWLDGQKSHALWVKPPLKVQLTPTKATS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of polyesters containing 2,4-dihydroxy-6-(2-hydroxypropyl)benzoate and 3-hydroxybutyrate moieties, such as talapolyester G, 15G256beta and 15G256beta-2; as well as to oxidized derivatives such as 15G256alpha (PubMed:35889347).  The biosynthesis of the polyesters probably starts with the formation of the diketide 3-hydroxybutyryl-S-ACP catalyzed by the partially reducing polyketide synthase tpeA (Probable).  The acceptance of 3-hydroxybutyryl by the non-reducing polyketide synthase tpeB would initiate further elongation and cyclization, catalyzed by KS and PT, respectively, to form 2,4-dihydroxy-6-(2-hydroxyn-propyl)benzoyl-S-ACP intermediate (Probable).  The TE domain could catalyze lactonization at this step to yield 6-hydroxymellein as a derailment product (Probable).  The polyesterification process maybe occurs when additional molecules of 3-hydroxybutyryl are transferred to tpeB (Probable).  Following the first esterification step, an intramolecular cyclization catalyzed by the TE domain of tpeB would give talarodioxadione 1, whereas the ethyl esterification of talapolyester G perhaps happens spontaneously (Probable).  Further oxidation by the cytochrome P450 monooxygenase tpeC then leads to the formation of oxidized derivatives (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase tpeC, Polyesters biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: Y3753_AZOC5
Sequence: MMIHIPKVLTPEQVARCRAVMDAAGWVDGRSTAGAQAVHVKKNLQLPDGSAEARELGEMVRAALQRSALFTSAVLPRRILPPMFNRYDAGMTFGSHVDNAIRFVRDSGEPLRTDVSTTLFLSEPDEYEGGELVVEDTYGAHKVKLPAGDAIVYPATSLHHVTPITRGSRVASFFWTQSLIRDAGQRALLFDMDMAIMRLNQDHPGHISAVQLTGVYHNLLRQWAEV
What are the official names of this protein?
PKHD-type hydroxylase AZC_3753.
Protein: PGK_MACCJ
Sequence: MVKKVVSDLELKDKKVLVRADFNVPMKDGNITNDNRIVEALPTIKYIIEQGGKVILFSHLGKVKTEEDKANLSLQPVANRLSELLDKEVQFVAETRGEKLESAINALQPGDVLLFENTRFEDVDGKKESKNDAELGKYWASLGDVFVNDAFGTAHREHASNVGVATHLDTAAGFLMEKEIKFIGGVVENPERPFVAILGGAKVSDKIGVIENLLEVADKVLIGGGMAYTFLKAQGKEIGHSLLEEDKIDLAKDLMERGKDKLVLPIDAKVTKEFSNDGEIEAVAIDHIPADLQSLDIGPKTVELFGKELEGAKTVVWNGPMGVFEMSNFAKGTVGVCKAIAELKGATTIIGGGDSAAAAMDLGFADKFTHISTGGGASLEYLEGKELPGIKSISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_SPHAL
Sequence: MRYLPLTPDDRAAMLGAIGASSIDELFADVPAGARLDGPIAGLPMHASELAVERHMGALARRNRAAGDGPFFLGAGAYRHHVPASVDHLIQRGEFLTAYTPYQPEIAQGTLQMLFEFQSQVARLFGTDVANASMYDGSTACWEAIVMARRITRRSKALLSTGLHPHYRSVARTMAKYTRDVLVDGDPRLEPGTDWAALAGRIDTETSCVVVQYPDILGRIDDMTTLAEACQTAGALLIAVVTEPVALGLIKSPGEMGADIVVGEGQSLGVGLQFGGPYVGLFACKSKYVRQMPGRLCGETVDANGKRGFVLTLSTREQHIRREKATSNICTNSGLCALAFSIHMTLLGEAGLRQLATINHGRAKAAATELAKVPAVSVMNDSFFNEFTLLLPTAARPVVHRLAEQDILGGVSLGRLYPDTAALENGLVVAVTETVTEADIAAFAAALKEVLA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.