PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_CERS1
Sequence: MTSSDPTLRPERLPEDMDRALRPQSLEEFVGQAEARANLRVFIESARMRGEAMDHTLFHGPPGLGKTTLAQIMARELGVGFRMTSGPVLAKPGDLAAILTNLEPRDVLFIDEIHRLSPVVEEVLYPALEDFALDLVIGEGPAARTVRIDLQPFTLVGATTRLGLLTTPLRDRFGIPTRLQFYTEDELDLIVARGARMMGVDSDPEGTREIARRARGTPRIAGRLLRRVVDFALVEGDGRLTQAIADRALTRLGVDHLGLDLGDRRYIGLIAENYGGGPVGIETIAAALSESRDAVEEVIEPYLLQQGLIQRTPRGRMLAHKAWRHMGIEPPKGPGQSDLFG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AP4S_DICDI
Sequence: MAIKYFLLVNIRGKTRLSQYYESIPFEERPAMESEIIRKCLSRTEIQCSFVEYKDYKVIYRKYATLFFIVGVDTTENELAILELIHNYVEILDSCFDNVIMFNLDKAHFILDEMVSNGDIVEISKQHILEFVNLLYKQE
What is the function of this protein?
Probable component of an adaptor protein complex.  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways.
What are the official names of this protein?
AP-4 complex subunit sigma, AP-4 adaptor complex subunit sigma, Adaptor-related protein complex 4 subunit sigma, Sigma subunit of AP-4, Sigma4-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Protein: RL18_PROM3
Sequence: MSNLSRKQQTQKRHRRLRRHLNGTAQRPRLAVFRSNNHIYAQVIDDEAQNTLCAASTLDKDLRTSLKADGSSCDASNAVGDLVAKRALAKGIQQVVFDRGGNLYHGRVKSLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: EFP_STAEQ
Sequence: MISVNDFKTGLTISVDNGIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEQAMIENRRMQYLYADGDNHVFMDNETFDQIELPGDYLKDELNYLKANMEVQVQSYESEVIGVELPKTVELEVTETEPGIKGDTATGATKSATVETGYTLNVPLFVNEGDTLVINTSDGSYISRG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_RICBR
Sequence: MLLPEITLTLTALLSQFFAVMLQGKNRIVANITILLTILTIFIILKYSYSESVLYLDYVMFTTNANIANYKAIILIFTIISMIIYRDYSVRSGEPLKFEFITLILLSTVGIFVAISAQNFLLLFCAMELTALTSYILAGFKLSDIKSSEGALKYFILGSLVSCLSLFGISFIYGFGGSLQFSDIFYKLNDSSSVNLGLVIGVVLFLSSIFFKLSSAPLHFWAPDVYEGSPIASVTYFTAASKIGAVAILLNIENLIIKNYHPISYNLIKIIALLSMIFGALGAIRQTSLKRLMAYSTILNIGYVLIGVLLRTEDGNKAAMLYMLIYAAASIGFFTCLIMLLGNQTDKANFESIQGIAENHKAIAAAICIIMFSMIGIPPLAGFLGKYYLFYQAITQEEFLLAYFGIFTSVIAAFYYLKIIKTMYFAEKPNPTKIPISYGLLLINFVVIGFLLFGSFIISS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGA_SHIBS
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_WOLPM
Sequence: MSAKIKSGDDVIVLTGKDKGKIGKVIKVIARDAKKKVIVSGVNVHKRHTKPKAGSSGGILNKELAIDISNVATLDPKYKTPTRVGFKVIDGRKVRFAKVSGEVID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GLGA_ACICJ
Sequence: MRVLSVGSEIYPLVKTGGLADVMGALPAALSSEGITVRSLVPGYPAVTAALDRAESVLRIPDLFGGAAEIRAAAAGRHDLFVLDAPHLYARPGNPYIASNGVDWSDNAQRFAALCRAGALLARGAVGGFVPDLLHAHDWQAGLVPAYLHYEGHAAPPCVFTVHNLAFQGWFPAHLLGALGLPASAFVIDGVEYFGGIGFLKAGLQFADAITTVSPRYATEIATQDGGMGLDGLLRKRGSAVHGILNGLDTATWNPATDEHLAARYDVANLAARAVNKRAVQARMGLAPDPRALLFGVVSRLAGQKGIDLIIEALPVLDALGAQLAVLGTGETGIEASLREAVAARPGRVAAIIGFEESLSHLIQGGADAILVPSRFEPCGLTQLAAQRYGAIPVVSLVGGLVDTVIDANPVAISAGVATGIQFGPVSEAGLSDGLRRTAALYADPDKWSRMQRNAMALDVSWTEPARNYAALYRSLTSR
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SPT41_ARATH
Sequence: MGEAPAQIPTSFGHELRACLRCRLVKTYDQFRDSGCENCPFFKIEDDHERIVDVTTPNFNGIISMMDPRRSWAARWLRIGKFAPGCYTLAVSEALPEEMQFICQQARVQYVPPKRI
What is the function of this protein?
May regulate transcription elongation by RNA polymerase II.  May enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_STRZT
Sequence: MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: XERC_LISMO
Sequence: MIQEGKLEQQFFDYLHSERNYSVNTSTAYENDLLDFRRFLNEQAITTYQQVTFLDVRIYLTELKQKSFSRTTVARKISSLRSFYTFLLRENVINENPFTYVSHAKNQLRLPKFFYSEEMEALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLPDLDTSYQAILIRGKGNKERYVPFGAYAEDAITDYLPERVNLMSRYKKSHDALLVNHYGDPLTTRGIRYCLTKIISKASLTRKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2142_NEIMB
Sequence: MIQHAGLGYRRDLAEDFLSLSENSPICFIEAAPENWLKMGGWARKQFDRVAERLPLALHGLSMSLGGQAPLDTDLIDGIKEMMRRYDCTFFSDHLSYCHDGGHLYDLLPLPFTEEMVHHTARRIREVQDRLGCRIAVENTSYYLHSPLAEMNEVEFLNAVAREADCGIHLDVNNIYVNAVNHGLLSPEAFLENVDAERVCYIHIAGHDVETPELLIDTHGAAVLPTVWDLLELAYAKLPTIPPTLLERDFNFPPFSELEAEVAKIADYQTRAGKECRRAA
What are the official names of this protein?
UPF0276 protein NMB2142.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: TX10C_MANRB
Sequence: MRLSYVSLTLAIIFVMAIVHAPETEAKAYPEADAVGEASAVGEADAVGVADPGVGSLLAKAALKILKIVAPAAAEVIANKIG
What is the function of this protein?
Induces paralysis 5 minutes after injection into blowflies (L. caesar) (PubMed:32182430).  In most cases is not lethal 24 hours after injection, but paralysis is irreversible (PubMed:32182430).  May have antimicrobial properties, like most ant linear peptides (By similarity).
What are the official names of this protein?
U10-myrmicitoxin-Mri1c, U10-MYRTX-Mri1c.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPC_ERWT9
Sequence: MSQLRPAVFLVLLLTLITGLLYPLLTTTLAQWMFPQQANGSLLLEQGSVRGSAPIGQSFSRADYFQGRPSATSDRPYNPLASSGSNLAGSNPALDQAVSQRVAALRAANPQAGQQVPVDLVTASASGLDPQISPQAAYWQADRIAAARRLPREVVKRLIDENTTTPMPAFLGEPAVNVLALNLALDALQR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TNAA_ECOHS
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIDVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: SPY2_CHICK
Sequence: METRVQHGSGSQALLQARRDSGRPHGEPDLRDVLTQQVHILSLDQIRAIRNTNEYTEGPTVAPRPGVKSAPRSASQPKSERPHGLPEHRHFGRVQHTQTHASPRAPLSRSISTVSTGSRSSTRTSTSSNSSEQRLLGSSSGPVADGIVRMQPKSELKSSELKPLSKEDLGAHSYRCEDCGKCKCKECTYPRTLPSCWICDKQCLCSAQNVVDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVVSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKHSNTVCCKVPSVPPRNFEKPT
What is the function of this protein?
Acts as an antagonist of FGF-induced retinal lens fiber differentiation (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (By similarity).  May play an important role in FGF-mediated patterning of the mid/hindbrain region by acting to modulate the signaling effects of FGF8 (PubMed:10662503).
What are the official names of this protein?
Protein sprouty homolog 2, Spry-2.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
Protein: Y2942_XANAC
Sequence: MLLPIPDVLSPAQLSQLRAQLDVADWADGRITAGHQSAQAKDNAQLPEDSAVAREAGALVLEALARSSTFFSAVLPRRIYPPLFNRYSGGQSFGYHVDNAVRYDRSRGGAEAVRTDVSATLFLSDPDSYDGGELVIEDTYGTQSVKLPAGHLVIYPGTSLHRVMPVTRGARVACFFWAQSMLRDAAQRRLLFELDVSIRRLTQDTPGHPSLIQLTGVYHNLLRQWADV
What are the official names of this protein?
PKHD-type hydroxylase XAC2942.
Protein: AAMT3_MAIZE
Sequence: MPMRIERDLHMATGNGETSYTKNSRIQEKVMFQIKPVLEEATRAAYSALLPQTMVVADLGCSSGPNTLRFVSEVIGIIARHCKEHDRRHDYPQLQFFLNDLPGNDFNNLFLLIQQFNKSMARNHKGEAAEALPPCYISGLPGSFYTRIFPSESVHLFHSLFSVHWHSQASEQLKDTKNKCLDIYITKNMPPSMVKLFQQQFEKDFSLFLKLRYEELVSGGQMVLTFIGRKHEDVFTGESNHLYGLLAQSLKSLVDEGLVEKEKLESFYLPIYSPSVGEVEAIVKQVGLFNMNHVKVFEINWDPYGDSEGDDVHDSIRSGENVAKCLRAVMEPLVASQFGEHILDKLFKEYARRVAKHLENEKTKHAILVLSIEKAIIHV
What is the function of this protein?
Methyltransferase involved in the biosynthesis of methyl anthranilate in response to stresses.  Utilizes anthranilic acid as substrate.  Produces exclusively the O-methyl ester.  Can also use benzoic acid as substrate.  Low activity with salicylic acid.
What are the official names of this protein?
Anthranilate O-methyltransferase 3, Anthranilic acid methyltransferase 3, Benzoate O-methyltransferase, O-methyltransferase 3, Salicylate O-methyltransferas.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family. SABATH subfamily.
Protein: ISCA2_BOVIN
Sequence: MAAVRGLTAVALRVVTPWQRSRLLAASRGPRALREVSFSSPEAGEGQIHLTDSCVQRLLEITEGSEFLRLEVEGGGCSGFQYKFSLDTVINPDDRVFEKGGARVVVDSDSLAFVKGAHVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSVKL
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.  May be involved in the binding of an intermediate of Fe/S cluster assembly.
What are the official names of this protein?
Iron-sulfur cluster assembly 2 homolog, mitochondrial, HESB-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CUTC_XYLFA
Sequence: MSFDVYVIRVFGKSRGSREAGMSVSAGLEVAAGSVASALAAQEGGAMRVELCHGLGGGGLTPSYGMLAVVRERLHIPLYVLIRPRGGDFVFSEEEMEVMCCDVECCVRLGCDGVVLGALDPAGEVDMGMMRVLIAVAGSLGVTFHRAIDVSADPGRTLEDVIALGCERVLTSGGRSSALEGAETIAALVAQAAGRVVVMPGAGVSAGNVLELRVRTGAHEFHASARSVVAARRLGPHPDIHDLGGDYDCTDVDKVRQLVRLLSQGAS
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBHB_ASPFC
Sequence: MLASTFSYRMYKTALILAALLGSGQAQQVGTSQAEVHPSMTWQSCTAGGSCTTNNGKVVIDANWRWVHKVGDYTNCYTGNTWDTTICPDDATCASNCALEGANYESTYGVTASGNSLRLNFVTTSQQKNIGSRLYMMKDDSTYEMFKLLNQEFTFDVDVSNLPCGLNGALYFVAMDADGGMSKYPTNKAGAKYGTGYCDSQCPRDLKFINGQANVEGWQPSSNDANAGTGNHGSCCAEMDIWEANSISTAFTPHPCDTPGQVMCTGDACGGTYSSDRYGGTCDPDGCDFNSFRQGNKTFYGPGMTVDTKSKFTVVTQFITDDGTSSGTLKEIKRFYVQNGKVIPNSESTWTGVSGNSITTEYCTAQKSLFQDQNVFEKHGGLEGMGAALAQGMVLVMSLWDDHSANMLWLDSNYPTTASSTTPGVARGTCDISSGVPADVEANHPDAYVVYSNIKVGPIGSTFNSGGSNPGGGTTTTTTTQPTTTTTTAGNPGGTGVAQHYGQCGGIGWTGPTTCASPYTCQKLNDYYSQCL
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Probable 1,4-beta-D-glucan cellobiohydrolase B, Beta-glucancellobiohydrolase B, Exocellobiohydrolase B, Exoglucanase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY_XYLFA
Sequence: MKQYLELLNDVLVHGIQKPDRTGTGTRSVFGWQMRFDLSQGFPLVTTKKLHLRSIIHELLWFLRGETNIAYLKKHQVHIWDEWADATGELGPVYGKQWRRWAGADGHEIDQIRWLLEEIKRNPDSRRLVISAWNVADLPQMALVPCHALFQFYVANGKLSCQLYQRSADIFLGVPFNIASYALLTHMLAQVTGLAVGDFVHTLGDAHLYANHVEQASVQLERVPRPQPVLMLNPAVTDLFDFTYDDIVIEGYDPYPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_GLAP5
Sequence: MEKLDSLNEAFKSLLREEKFGSQSEIVTALQEMGFEHINQSKVSRMLSKFGAVRTRNTKMEMVYHLPAELGIPTTSSPLRNLVIDIDHNESLIVVRTSPGAAQLIARLLDSMGKAEGILGTIAGDDTIFITPTRDTSISTLIATITELFDSSL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_AZOVD
Sequence: MLKVGIVGGTGYTGVELLRLLAQHPQVEVAVITSRSEAGVKVADMYPNLRGHYDGLAFSVPDSAVLGSCDVVFFATPHGVAHALAGELLAAGTRVIDLSADFRLQDAEEWARWYGQPHGAPELLPEAVYGLPEVNRERIRSARLIAVPGCYPTATQLGFLPLLESGLADNARLIADCKSGVSGAGRGAKVGSLFCEASESMMAYAVKGHRHLPEISQGLRRAAGGEVGLTFVPHLTPMIRGIHATLYASVADRSVDLQALYEKRYASEPFVDVMPAGSHPETRSVRGANVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQAVQNMNILFGLDERLGLAHAALLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_JANSC
Sequence: MSMNSYGHLFRVTTWGESHGPALGATVDGCPPGIDVDAAAIQHWLDRRKPGQNKYTTQRREADEVEILSGVYEGQSTGTPIQLMIRNTDQRSKDYGDIAEKFRPGHADITYWQKYGIRDPRGGGRSSARETAARVAAGGVARLALAALVPAVKITGYMVQMGPHGIDRECFDLAQVDENPFWVPDAKAADEWAAYLDGLRKSGDSVGAVIEVRASGLPAGLGAPIYGKLDTDLAAAMMSINAVKGVEIGDGMAAAALTGSANADEIHMGDNGPEYSSNHAGGILGGISTGQDVIVRFAVKPTSSILTPRATITKAGTPAEIITKGRHDPCVGIRAVPVGEAMMACVVLDHILLQRGQIGGKVGETRGKIG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GLPK2_THEMA
Sequence: MKYVLSLDQGTTSSRAIVFDEKGNVVSKVNKEFRQIYPRPGWVEHDPVEIWESQIEVAKKAIEEAGIKPEDIAAIGITNQRETTIVWDKNTGKPVYNAIVWQCRRTAPICDELKEKGYSEFIRERTGLVIDAYFSGTKIKWILDNVEGVREKAEKGEVLFGTVDTWLIWNLTGGRVHVTDYSNASRTMIFNIHKLDWDDEILELLNIPRAMLPQVMPSSHVYGYTAKDIFGVEIPIAGDAGDQQAALFGQACFQPGMLKNTYGTGCFLLMNTGEKAFESKSGLLTTIAWGINGKVYYALEGSIFITGAAVQWLRDGLKIISNAAETEELATKVPDNGGVFFVPAFVGLGAPYWDMYARGLIIGITRGTTREHIVRAVLESIAYQTRDVVEVMEKDSDIKVETLRVDGGAVVNNFLMQFQADILGVPVERPVVNETTALGAAYLAGLAVGYWKDQEEIASLWQLDRRFEPSMNSEERERLYSKWKEAVSRSLGWEKR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase 2, ATP:glycerol 3-phosphotransferase 2, Glycerokinase 2, GK 2.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GFRA4_HUMAN
Sequence: MVRCLGPALLLLLLLGSASSVGGNRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLLDQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL
What is the function of this protein?
Receptor for persephin.  Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.  May be important in C-cell development and, in the postnatal development of the adrenal medulla.
What are the official names of this protein?
GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
[Isoform GFRalpha4a]: Cell membrane; Lipid- anchor, GPI-anchor. SUBCELLULAR LOCATION: [Isoform GFRalpha4b]: Cell membrane; Lipid- anchor, GPI-anchor. SUBCELLULAR LOCATION: [Isoform GFRalpha4c]: Secreted.
Protein: GLGB_PROMP
Sequence: MKETIQADWIKSEAFNLENCCNDNPLNILGPHFVNGQWITRVWMPEADEVNIIFKDKTYKTTTLNHKWLFEVTLPEDPKNNYQINVSRGGVSHSQQDPWAYRKEWMGELDRHLFAEGNHHHIWEKMGAHIHEETNQQGVMFCIWAPNAKSISIIGDINSWDGRHHPMQKRLGGIWELFMPIMKEGDAYKYEIRTQEGHIYEKADPYGFLHEIRPQNGSIVSKLNNFDWEDSSWITNRDSSSQINKPISVYEMHLGSWMHDSIENKYIEKNGQTRSPVPAADLKPGTRFLTYPELTEKLIPYVKERGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRYGTPNEFKEFINRCHAEGIGVILDWVPGHFPKDKHGLAFFDGCHLYEHGDPRIGEHKEWGTLIFNYSRNEVRNFLVANLIYWFEEFHIDGIRVDAVASMLYRDYLRPEGEWIPNENGGNENLEAVKFLQQANHVLFQHFPGALSIAEESTTWPMVTEPTNVGGLGFNLKWNMGWMHDMLDYFEIDPWFRQFHQNSVTFSITYNYTENFMLALSHDEVVHGKSHLLHKMPGDDWKKFANTRALLTYMWTHPGKKTIFMGMEFGQRQEWNVWDDLQWELLEFEPHKGIRNLVDDLNKLYKNEPSLWKNDFDPYGFQWIDCNDTSNSVISFMRRENESNEWLVIVANFTPNFHGSYKIGVPLEGFYKEIFNSDGSKYGGSNKGNMGGKETLKYNIHNYENALEIVLPPLSVSIFKHQLKQ
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.