PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_IDILO
Sequence: MAIWGLGTDIVEVARIEQSLARGNSLVKRVLTPKEQEEMTASVDEAAFLAKRFAAKEACSKAFGRGISAGLSFQHMQVVHNEYGKPEWHFTETAAQWVKEQGISGSHLSISDEKHYAVATVILETD
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_MARMM
Sequence: MKFLDQAKVYVRSGNGGGGCVSFRREAYVEYGGPDGGDGGKGGDVWVEAVEGLNTLIDYRYKQHFKADTGMHGMGRNRTGSGGEDVVLQVPAGTQLLDEDKEEILADLTEIGQRVLLARGGDGGKGNSHFKTSTNQAPRKTIPGWPGEERWIWLRLKLIADVGLVGLPNAGKSTFLSVVSKANPKIAAYPFTTLYPNLGVVDLGPGSRFIVADIPGLIEGAHEGAGIGDRFLGHIERCASLIHLIDGTQDDVVAAYKTVRGELEAYGDGLPEKQEILALNKIDAMDEAMVAEKRAELEAASGKTVMTLSGVSGDGVKALCGSAWDIVLQNRRAEKAAAEAAEKGEEGWAPS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_NITEU
Sequence: MANTLPPTDRSCDISQPLERLSPDESLKAESDYLRGTIALGLLDRITSAVPGNDIKLMKFHGIYEQDDREIRDERRRQKLEPAFQFMIRVRLPGGICTTERWLKISELACAHGNETLRMTTRQTFQFHWVLKQNIVPLIRGLHEVLLDTVAACGDDSRGVMATVNPQFPALQAELAALAKTVSDHVIPKTRAYHEIWYGEERIASSEPEEPFYGQTYMPRKFKIGFVIPPNNDIDIYAQDLGYIAIIGENGKIAGFNVAIGGGMGRTDKAPHTYPRTASVIGFITPDRLISVTEAVMGVQRDYGNRADRSRARFKYTIDDKGLDWIKLAIEDRAGPLESARPYDFTSNADIYGWIESGDGFHHFTLFIENGRLNRDMLDKIAQIAHVHKGHFRLTPNQNLMIANVATADKPEIEALLRETGLIAFNERSVLRLNSMACVALPTCGLAMADSERYLPDLITKIEGILTRYNLQNEPITLRMTGCPNGCSRPFIAEIGLTGRAPGKYNLYLGGGFHGQRLNRLYRENIGEPAILETLNEVLGRYATERLPDEHFGDFTIRAGIIREVTEGRFSND
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: DER_THISH
Sequence: MLPVIALVGRPNVGKSTLFNQLTRSRDALVADFPGLTRDRQYGPGRVGGFPYMVVDTGGLSGEAETLDNLMARQTQQAIDESDVVLFLVDGREGLTAADQAIARSLRTQGKKVLLVVNKTDGVDADQAMAEFHALGFGAPIPIAATHGRGVLGLMNAVHALLPEVEEIQAEAERWPGIRIAFVGRPNAGKSTLINRILGEERVVATEIPGTTRDSIFIPFERDGQQYTLIDTAGVRRRSRVHEAIEKFSVVKTLQAIDAAHVVVMVLDAREGISEQDAHLLGVVLDAGRALVVAINKWDGLDPDQRDRIRHELDLKLPFLDFAEKRFISALHGTGVGDLFAHVKRAYDSAFIKVSTNHLTKLLESAMVAHQPPLVSGRRVKLRYAHQGGQNPPIIVIHGNMTERLPGSYKRYLSNHFRQHLKLVGTPIRLEFKTGENPYAGKRNVLTPRQQYKRKRMMRHAKKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: COX1_CHLRE
Sequence: MRWLYSTSHKDIGLLYLVFAFFGGLLGTSLSMLIRYELALPGRGLLDGNGQLYNVIITGHGIIMLLFMVMPALFGGFGNWLLPIMIGAPDMAFPRLNNISFWLNPPALALLLLSTLVEQGPGTGWTAYPPLSVQHSGTSVDLAILSLHLNGLSSILGAVNMLVTVAGLRAPGMKLLHMPLFVWAIALTAVLVILAVPVLAAALVMLLTDRNINTAYFCESGDLILYQHLFWFFGHPEVYILILPAFGIVSQVVSFFSQKPVFGLTGMICAMGAISLLGFIVWAHHMFTVGLDLDTVAYFTSATMIIAVPTGMKIFSWMATIYSGRVWFTTPMWFAVGFICLFTLGGVTGVVLANAGVDMLVHDTYYVVAHFHYVLSMGAVFGIFAGVYFWGNLITGLGYHEGRAMVHFWLLFIGVNLTFFPQHFLGLAGMPRRMFDYADCFAGWNAVSSFGASISFISVIVFATTFQEAVRTVPRTATTLEWVLLATPAHHALSQVPVLRTASSH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TGT_XANAC
Sequence: MSRLQFQLQATDGHARRGRLTFPRGTVETPAFMPVGTYGSVKGILPEQIRALGAEIILGNTFHLYLRPGLEVIGDHGGLHGFARWDGPILTDSGGFQVFSLAHRRKITEQGVTFSSPTDGARVFLGPEESMKIQKVLDSDIVMIFDECTPYPATEDVARRSMELSLRWAQRSRDAHDGLGNDAALFGIVQGGVHPDLRSRSLDGLQAIGFDGYAIGGLAVGEPEHERNAMLEHLHPRLPAERPRYLMGVGRPEDLVEGVARGVDMFDCVMPTRNARNGHYFTSFGTVRIRNAKYERDLDTIEPGCGCHACSSGYTRAYLRHLDRCNEMLAPMLGTLHNLWYYEKLMADMRAAIASGTFVEFRRSFYAARGATTPPLPGETS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: AKH_HELZE
Sequence: QLTFTSSWG
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, Hez-AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHG28_MOUSE
Sequence: MEVEDSGGVVLTAYHSHARSQPQGAEPRCASRASHPLSRKSIPRCRRINRMLSNESLHPPSFSRSNSQASVDSSASMEEFLREIESIKESSVGASQEQPPTAAAAAAEVKPVDEGELEAEWLQDVGLSTLISGNEEEDGKALLSTLTRTQAAAVKKRYNTYTQTLRKKNKQPVRDVRDIFGVSESPPSDSCEHATQLDGTKEEKDLPGVTKTSRPLPDDASLSSTTLSNGAQDEEGGFVALQSGSVSILEAIPDIAVHTNGSADAEQSVQSTLSDDDYHGKNVPAEAEELSFEVSYSEMVTEMPDRNKWKKSDIKKEDYVLTKFIIQKTRFGLTETGDLSVEDMKKIRHLSLIELTAFFDAFGIQLKRNKTERVRGRDNGIFGVPLTVLLDNDRKKDPAVKVPLVLQKFFQKVEESGLESEGIFRLSGCTAKVKQYREELDARFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYIPAFISLMERGPDIKVQFQALHLMVMALPDANRDTAQALMAFFNKVIANESKNRMNLWNISTVMAPNLFFSRSKHSDCEELLLANTATHIIRLMLKYQKILWKVPSFLITQVRRMNEATMLLKKQLPSMKKLLRRKTLDREVSILKTSKVPQKSPSSRRMSDVPEGVIRVHAPLLSKVSMAIQLNSQTKAKDILAKFQYENSHGSSEHIKMQNQRLYEVGGNIGQHCLDPDAYILDVYHINPHAEWVIKP
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 28, Rho-type GTPase-activating protein 28.
Protein: YOSJ_BACSU
Sequence: MIQGFYKDQKLHLLEDPMQQYTVMKVEENAVCVYRWIDDYRHKIERFTDVEEAKKLLGEGWPKQ
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YosJ.
Protein: RAVA_ECO55
Sequence: MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEADSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKEIGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDLILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKTALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERNALEQWLSKGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQLEELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC
What is the function of this protein?
Functions as an ATPase.  May play a role in metal insertion (metal-chelatase) or as a chaperone.
What are the official names of this protein?
ATPase RavA, Regulatory ATPase variant A.
What is the protein family that this protein belongs to?
Belongs to the RavA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_YERPP
Sequence: MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_BACTN
Sequence: MKFLGIIPARYASTRFPAKPLAMLGGKTVIQRVYEQVAGILDDAYVATDDERIEAAVKAFGGKVVMTSIDHKSGTDRCYEACTKIGGDFDVVVNIQGDEPFIQPSQLNAVKACFEDPTTQIATLVKPFTADEPFAVLENVNSPKVVLNKNWNALYFSRSIIPFQRNADKEDWLKGHTYYKHIGLYAYRTEVLKEITALPQSSLELAESLEQLRWLENGYKIKVGISDVETIGIDTPQDLKHAEEFLKNRS
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA1A_CONMA
Sequence: DGRCCHPACAKHFNC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like MIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_SHIFL
Sequence: MSFDIAKYPTLALVDSTQELRLLPNESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLVILNFGTLMPETAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: HEMA_INBIN
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALARPKCTGTIPSAKASILHEVKPVTFGCFPIMHDRTKIRQLPNLLRGYEHIRLSTHNVINAETAPGGPYKIGTSRSCPNVTNGNGFFATMAWAVPKNDNNKTATNPLTVEVPYICTEGEDQITVWGFHSDNETQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: Y2544_DICDI
Sequence: MEDSDKENTLLLPNNKYRNQNFIRNQDEDENENENNDNLENDNNKRNYISINNYEPYKEIDNNNNKNNNNNNIINNNNKINFYNNLIPRIKSYFQEIKPFLKYCSFSFLFSFDPSEPYLVDYFTNVLGINQTIVYQEIYPYWTYSYFVFLLIFGILGEIIGYKVIIIIGMVAKILTIGVLLSTNNIIWMILEQITEGLSYSAYTVFLAYIYFSLDTSEYQKMACRVNAGYLVGIVSSGLLGQLLVEQRLPLVYLLSIACGTNILALILALGFSNYKIDQKFSLKEVISDLFGTFKNADIVRWYIWSGIAISIHQIVITYWQNLFLQVNDEQSWNGYISASAYFFASFFAIIPSKLGNKINNIQGIILVLFGLLGGGLLVLMGFGGSTVVSALSFIIYNCCFEFVSPIVNVQIAKKLSSRIGVLFSFNIMVALTIQVLVQSAVGKQFLNLDIKTQFYYYGACLFFLSFGFAILFGFLFLKKKINSNSNSNSNVDVLIVNHNTQNQNSEEKKKKKELYYNANIIDFENNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNVGIGGNDNFK
What is the function of this protein?
Folate transporter.
What are the official names of this protein?
Folate-like transporter DDB_G0272544.
What is the protein family that this protein belongs to?
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CBP4_PICGU
Sequence: MSTRPLWYRWARVGFYGGAIIATGVVLFKYTTPTDEQLIASFSPEVRAEYEKSRELRQKEQQALMEIVKKTSASNDPIWKTGSIKSPFEKDGRYVDPKLVDPQALLRESAAEQQRIETEEANRKMEETERLLNEKRKKWWSWK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HIS2_RHIWR
Sequence: MTGTLDQLESTIAARRAADPSTSYVAALFAKGMPKIAQKLGEEAVETVIAAMAGDRRGVTGEAADLLFHLMVLLAEAGVPFADVLAELDRREGTSGLAEKAARPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_LACLM
Sequence: MVLAKDLKSGMTFLNGEKLLRVMEASHHKPGKGNTIMRMKLKDVRSGSTFDDTYRPEDKFEQAVIETVTAQYLYSMDDIANFMNNETYEQYEIPVEQVKDELLYVLENTDVKIQFYGTEVIGIQLPTTVVLEVTETQPSIKGATVTGSGKPATMETGLVVNVPDFVEVGTKLEINTQTGEYLKRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANCY_SYNP6
Sequence: MRQLISPEALRAFRQSVQGSVGFVPTMGALHAGHRSLIERSRQQDDVVIVSIFVNPRQFGPQEDLSRYPQTLDADLALCEAAGVDAVFCPTAEALYPRPSDRSTGVQPPAELIQSLCGRQRPGHFQGVATVVLKLLQLVQPQRAYFGEKDAQQLRVIQRLVEDFNLPIAIVPCPTVREPDGLALSSRNRYLTFEERSQASGLYRALRAAAECFQAGSRDSQELVAAATAVLATTPAVQLEYCDCVDADSLQPLTQIPDRALLAIAARVGTARLIDNLTLQGRRPIIAIDGPAGAGKSTVTKRLAQQLGLLYLDTGAMYRAVTWLVQQQGIDPQDPIVLAELLAQADLQLRSQPAADGSEQLQVLIQGNDVTAAIRTPTVTAQVSAIAALPLVRQFLVEQQRQLGQRGGLVAEGRDIGTHVFPDAELKIFLTATNAERARRRALDLEAQGLTVDLAQLEAEIRDRDRQDSERAIAPLCKAEDAVEVLTDGLSIEAVTDQIIRLYRDRGLGDSSPQATPGQTPSPLSLG
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B9D1_RAT
Sequence: MAAASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAGLEEGISQIASKSQDVRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMKKLGYDTGPVDTQGVLSPSLPQGNPQ
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
B9 domain-containing protein 1, Endothelial precursor cells protein B9.
What is the protein family that this protein belongs to?
Belongs to the B9D family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: PURA_CAEEL
Sequence: MGSVTSKTNDELESFLNKRLGGSMTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILEESGWEKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAELKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQYVKFIEDFIKVPIVYIGVGAERESLIVRQQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_SHIDS
Sequence: MAKTLYEKLFDTHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERALAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MURA_HELPY
Sequence: MDFLEIVGQVPLKGEVEISGAKNSALPILAATLLSRQEVKIKSLPQVVDIKAMALLLQNLGASLEWLNPNTLQIGAKSLNHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAKITIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCAFLQSGGVEIHGIGSSELKIRGVENDALNLKDIQIIPDRIEAGTYLCVGAITNSQLKINHIIPNHLQAITDKLIEIGFSLDIQENSIEIHPAKKRQAFEITTKEYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNVATISGSTELTGSDVMATDLRASSALVLAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVARLKEK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHHS_SALTY
Sequence: MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQYFATLLSRPHAGRYADVLGPKKIVVFGLCGCFLSGLGYLLADIASAWPMISLLLLGLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGVALLAVLLALPRPSVKANKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSVAFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLLVGTAAMPWMAKIGVLLTGMGFSLVFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTGPLAGLVMTWAGVPVIYLAAAGLVAMALLLTWRLKKRPPSALPEAASSS
What are the official names of this protein?
Uncharacterized MFS-type transporter YhhS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_COREF
Sequence: MRVLAAMSGGVDSAVAASRAVAAGHEVVGVHLALSRDPQSVRESSRGCCSLEDSADARRVCDKLGIPFYVWDFSDRFKEDVIDDFIDSYAIGETPNPCLRCNEKIKFAALLERGIALGFDAVVTGHYARLTQPADGGDGYLRRGVDMNKDQSYVLGVLGAHEIAHCMFPVGDTVKPEIREEAAASGFSVAKKPDSYDICFIPDGNTQAFLGKHIGLRPGMIVDREGTTLREHAGVHEFTIGQRKGLDIKEPAADGRPRYVTDIDAATGTVTVGSREDLEVGVIHADRLKFLHPAMDGELDCEVQVRAHGGVVKCHARIDRTADTMRLDLAESLSGVARGQAAVLYLPDPEGDIVLGSGTICGTEA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMA_RAT
Sequence: MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD
What is the function of this protein?
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
What are the official names of this protein?
Prothymosin alpha.
What is the protein family that this protein belongs to?
Belongs to the pro/parathymosin family.
What are the subcellular locations of this protein?
Nucleus.