PharMolix/UniProtQA huggingface dataset:
Protein: PANCY_SYNJA
Sequence: MQWLRTVAALREQVASWRGSTIGLVPTMGSLHEGHLSLIRRCRQECDHTVVSIFVNPLQFGPNEDWDRYPRDEEGDRALCEAAGVDVVFAPDPQEMGADPATAGDRTWVMPPESLLQTLCAPHRPGHFRGVATIVLQLLNLVQPQRAYFGQKDAQQLAIIQRLVQDLQIPTTIVPCPTVREADGLAYSSRNRYLSAVERQVAASLYRALRRGYDHWQAGDPSAEGILAAARAELERTPELRVQYLELVDPQTLQPLSEVKDKGLLAIAAYVGQTRLIDNLLLSPEGVDPLPQEQQSAVPPSPKRGRRPLIAIDGPAGAGKSSVARAVAAQLQLLYLDTGAMYRAITWLALQRGIPLDDAEQLTQLAAQTQLTLQSGPSADEPTRIWADGEEVTQAIRSPEVTRWVSQVAAVPGVRQELVKRQRLIGRDGGAVLEGRDIGTHVFPDAELKVFLTASVGERAQRRQHQLQAQGQVVSLEELKAQIEQRDRRDSERLISPLRPAPDAILIDTDHLSQAEVEDKIVRLYRQLLERSGAAHFDII
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN2A_LITSE
Sequence: GFISTVKNLATNVAGTVIDTIKCKVTGGC
What is the function of this protein?
Mast cell degranulating peptide.  Causes histamine release from rat peritoneal mast cells in vitro.  Has antibacterial activity against the Gram-negative bacterium E. coli K12 and Gram-positive bacterium M. luteus NCT C2665.
What are the official names of this protein?
Ranatuerin-2SEa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: FRDC_SALNS
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOAD_BACSU
Sequence: MIKILLFAGLAEQAGTQAIEIDMEQATTDEIKASLKEQYGLESIDTAMIAVNESYVKENTSVSSGDTVAIIPPVSGG
What is the function of this protein?
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, MPT synthase subunit 1, Molybdenum cofactor biosynthesis protein D, Molybdopterin-converting factor small subunit, Molybdopterin-converting factor subunit 1, Sulfur carrier protein MoaD.
What is the protein family that this protein belongs to?
Belongs to the MoaD family.
Protein: PRMA_METCA
Sequence: MWQQLMVTVDEDLAEDVSDALMDAGALSVSFLDAGDQPLFEPPPGTTPVWAQTRVVGLFEEGGDLAAIRSALGGRFGDERLRDWSEEALADQVWERTWLEHFRPMRFGSRLWVCPTGFTVEDTDAVVMSLDPGLAFGTGTHPTTALCLEWLDAADLQGASVLDYGCGSGILGIAAALLGAAGVHAVDIDPQALAATVENARKNRVGDRIEVASPGGLADFDSDIALANILANPLMELADALRSRVRPGGRIVLSGILAEQADAVASVYARKGFEMEPAVFREGWVRLAGVRRT
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_PSE14
Sequence: MIQIHALPAFNDNYIWLLQDLSSQQCAVVDPGDAKPVLGWLTEHPDYRLTDILITHHHNDHVGGVAELKQATRARVLGPAAETIPARDVALVDHDRLTVLGLEFVVHAVPGHTLGHIAFYHEDATTPLLFSGDTLFAAGCGRLFEGTPEQMHDSLERLAKLPDSTLIYCAHEYTLSNLRFAQAVEPDNQDIAQRLAEVIRWRSENRISLPSNLALEKRTNPFLRTRETSVKEKADERSSGQNTSQSAVFASLRAWKDKF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: MGSA_SALPB
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: COCH_CHICK
Sequence: MQFAPLLLGVFLLCGSARGSDSSASNAITCFTRGLDLRKETEDVLCPANCPLWQFYVFGDGIYASLSSVCGAAIHRGVITNAGGAVRVQTLPGQENYPAVHANGIQSQVLSRWASSFSVTPGTNNLALEAVGRSVATARPATGKRPKKTLEKKAGNKDCKADIAFLIDGSYNIGQRRFNLQKNFVGKVAVMLGIGTEGPHVGVVQASEHPKIEFYLKNFTAAKEVLFAIKELGFRGGNSNTGKALKHAAQKFFSMENGARKGIPKIIVVFLDGWPSDDLEEAGIVAREFGVNVFIVSVAKPTTEELGMVQDIGFIDKAVCRNNGFFSYQMPSWFGTTKYVKPLVQKLCSHEQMLCSKTCYNSVNIGFLIDGSSSVGESNFRLMLEFISNVAKAFEISDIGSKIATVQFTYDQRTEFSFTDYTTKEKVLSAIRNIRYMSGGTATGDAISFTTRNVFGPVKDGANKNFLVILTDGQSYDDVRGPAVAAQKAGITVFSVGVAWAPLDDLKDMASEPRESHTFFTREFTGLEQMVPDVIRGICKDFLDSKQ
What is the function of this protein?
Plays a role in the control of cell shape and motility in the trabecular meshwork.
What are the official names of this protein?
Cochlin, COCH-5B2.
What are the subcellular locations of this protein?
Secreted.
Protein: MATK_ERITE
Sequence: MEEFKRNLELDRSQQYDFIYPLIFQEYIYALAHDRVLKRSFFLENAGYNDKSSLLIVKRLITHLITQMYQQNHFLFSVNDSKQNPILGYNRNFYSQTIFEGFAVVVEIPFYLRLLSFLEGKERVKSYNLRSIHSIFPFLEAQIFHLNNILDILIPHPIHLEILVQTLRYWVKDASSLHFLRFFLYKYPIWNSLITPKKSSFSFSKRNQRFFLFLYNFHVSEYESIFVFLRTQSSHLLSISFETFLERISFYKKIELEVFTKSFKAILWVFKEPFLHYVRYRGKVILASKGTSFLMNKWKYYLVSFWQCYFYIWSQPIRIHINQLSNHSLDFLDYLSSVRLKPLMVRSQMIENAFLIETASKKFDTLIPITPMIGSLSKAQFCNVIGHPISKPVWAALSDSDIIERFAHIYRNISHYHSGYVKKKNLYRIKYILRLSCARTLARKHKSTVRAFSKRLGMGLLEEFFTDEEQVFYLTFPKASSTSGELYGRRIWYLDIICINDLANYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EF1A_ENCCU
Sequence: MATKVEDDSKPRLNACFIGHVDSGKSTTVGMLSYQLGAVDKREMEKYEKEAALNNKETFYLAYLTDKTDAERKRGITITTTLVNLPTEKFNINILDCPGHKDFVKNMVTGASQADVAVVIVPASGFESCVGVGGMLKTHIMISGILGCEKLIVCVNKMDEIPENKRMEKFNEVSAEMLRIVKRSHKDKNPIIIPISAFKGINLTKKGEKFEWFKGWKEKEGSSVIYTLEEALNYQDVPERHNDKPLRMPITKVCSIAGVGKIFTGRVEYGTITPNLKITIQPAGVVGETRSVEIHNKPRSMIPCGENCGVALKGGVIGEIDKVDAGHVISANDENKAVAYPGAKIRTIVVGRPKGLSPGYTPQINFGNCHSPGRIAKILSKVVGKEVHENPENVANGENFTGIVVFQKPLVIDKMERFQNLAKFALMDSNGVVGIGNVMEPLTRDQLLKDYGIDLNEDPKAAKKAASKKKA
What is the function of this protein?
GTP-binding component of the eukaryotic elongation factor 1 complex (eEF1).  In its active GTP-bound form, binds to and delivers aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.  In the presence of a correct codon-anticodon match between the aminoacyl-tRNA and the A-site codon of the ribosome-bound mRNA, the ribosome acts as a GTPase activator and the GTP is hydrolyzed.  The inactive GDP-bound form leaves the ribosome and must be recycled by its guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) before binding another molecule of aminoacyl-tRNA.  Required for nuclear export of aminoacyl-tRNAs.  May also be involved in translational quality control by targeting cotranslationally damaged proteins to the proteasome (By similarity).
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Eukaryotic elongation factor 1A, eEF1A, Translation elongation factor 1A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_EMIHU
Sequence: MNNLIMLVTNAVTLSEAAGGLFDFNATLPLQALQFILLTVLLTFIFYKPIGKLLEERETFISNNLAEASAKLLKADELCEQYETQLKEAKTGAQDVIAKAESEAKGIVAQEITQARADAASLIAQTNKELEAQKKLALQQLETQIDELSQLIKEKLLGKVVL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y6910_BRASB
Sequence: MAGHSQFKNIMHRKGRQDAMKSKLFGKLAREITVAAKLGTPDPAMNPRLRAAVVAARAENMPKDNIERAIKKALGGEGENYAEIRYEGYGPGGVAVIVEALTDNRNRAASDIRSYFTKSGGNLGETGSVSFMFDRVGIIEFDRSVASDDAVLDAAIEAGADDVISGEGGHEVYASPDSFHEVAKNLEAKFGEPRKAALTWKPQNTVSVDDETGEKLLKLMDLLNEHDDVQNVYANFEISDALMAKMGG
What are the official names of this protein?
Probable transcriptional regulatory protein BBta_6910.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PELUB
Sequence: MPTINQLLRKKRIKPVARNKVPALQKQPLKRGVCVKVYTTTPKKPNSALRKVARVRLSNGFEVTAYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHILRGNLDTQGVANRKKRRSLYGTKKGK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DCD2B_HUMAN
Sequence: MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS
What are the official names of this protein?
Doublecortin domain-containing protein 2B.
Protein: HMOX2_RABIT
Sequence: MSAEVETSEGVDEPEEKNFGENHIRMADLSELLKEGTKEAHDRAENTKFVKDFLKGNIKKEIFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCSEAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSAPASETVEDRIPVHDGKGDVRKCPYYAAGQVNGALEGSSCPFRAAMAVLRKPSLQLVLAAAVALAAGLLAWYYM
What is the function of this protein?
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin.  Biliverdin is subsequently converted to bilirubin by biliverdin reductase.  Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.  Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
What are the official names of this protein?
Heme oxygenase 2, HO-2.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: COMB_CLOK1
Sequence: MKIDIIISADDIKKEKILHKSVIVVDMLRATSVIITAINNGCREVIPVLTIEEALEIYHKNREKYVMGGERKALKIEGFHCSNSPLEYSRQVVENKTLVITTSNGTKAIKGSIMAKNILIGALINADEVANRSINLNNDVVIVNAGTCGQFSIDDFICSGYMINCVIKKIKVDLTDIARTALYIYEQNPDIITFIKKASHYKRIKKLKLYDDLEYCCRKDIIKIVPEYIDGIIKCNKLIY
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: TRMB_PSEAE
Sequence: MSDTPQSPAQDSLAEHDEARPMRTVKSFVMRAGRMTEGQQRGLDLGWPKFGLELSDEVQDFDAIFGRQAPRTFEIGFGMGHSTLEMAAAAPDIDFIGVEVHKPGVGALLNGLLTQGLGNVRVYSCDALEVLRHCVADASLDRLLLFFPDPWHKKRHHKRRIVQPEFAELVRRKLKVGGVLHMATDWEPYAEHMLDVMSAAPGYRNQAEDGRFVPRPQERPVTKFERRGERLGHGVWDLKFERVD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PS10_PINST
Sequence: SGLQLLDLSNNREVEML
What are the official names of this protein?
Putative disease resistance protein PS10, TIR-NBS-LRR.
Protein: COBS_SHESR
Sequence: MSERESWHKEIDLFLVAMGYFTRIPMPKWVEVDADKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLPAGVSVLLSMVTGVLLTGGFHEDGLADTFDGFGGGWTAEDKLRIMKDSRLGSYGALALMLVLMLKWQLLVELALYDPVVAGSAMIVAHTVSRVVAASLIFTEKYVRDDESSKSKPLAQHQGINELFILIASGVLVLLVLKGIAALSLLLVMIGLRRLIVVIFRRQIGGYTGDTLGAAQQICEIVCYFVLLVVGSIL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAC1_MELAO
Sequence: MKTFTSALALVVGMLAPGAVVAAPPSTPAQRDLVELREARQEGGKDLRPREPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNPYPKIDSGLKRRRWVEESEWLVR
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-1, Benzenediol:oxygen oxidoreductase 1, Diphenol oxidase 1, Ligninolytic phenoloxidase, Urishiol oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: RM13_YEAST
Sequence: MSSLLKLHCIRPLPQRSVWLSGYKQKARCIHSSAANGDFMSWFKRKKQEEHQEPVKDTKQLIKDIEEGTNEASSQSSSNNKNRLELIPENFIGEGSRRCKRQKELKLAVSSAPFNQWLSRDKITSDNQLDDMILQATEKTLGKVDQDVQFSDLVAKFQFTKFLQSKSGYLIPDYELTTLSTPLQFKRYIKEKILPSANDPKLAYKEAEPNAIHPFSDNYASPNIYVVNDVTSKEQKSKYDTIMKEIQKLEDDATRKALETARSA
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L13, mitochondrial, Mitochondrial large ribosomal subunit protein mL50, YmL13.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL50 family.
Protein: RL18_AZOVD
Sequence: MSVKKETRLRRARKTRLKMRELEVVRLCVHRSSQHIYAQVITADGGKVLASASTLDKELRGAATGNVEAAKKVGLLVAERAKAAGVTQVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: BIODA_EMENI
Sequence: MAPVGAALWRSLRAHQVYGANTDVGKTIVSTFLCNAVNRLKNQGKSAFLKPVSTGPLDEADDRHLQRHAPNTLTKCLYQFDEPVSPHIAAKTFAIPRDDEILSSVHRTLSDWANDGVGFALVETAGGVHSPGPNGNSQADLYRPLRLPIILVADSRLGGISSSISAYESLLLRGYDVHSVLLFKDDYYQNHEYLGNYFRGKSIPLVPVPAPPRRPQEQDPDSRARDLEALDKYYSSVTKSTDVVSLLDELVLKNKQRVEYLDEMASRAQKTIWYPFTQHHGMAAKDITPIDSAYDDFFQTYVTADRSAQQGRLQATFDGSASWWTQGLGHGNPGLALSAAYAAGRYGHVMFPGNIHEPALALAESLLKTVDNPRLQKVFYTDNGSTGMEVALKMGLRAACDRYGWDASKEQINILGLKGSYHGDTIGVMDCSEPSTYNQRVEWYRGRGHWFDFPLVKMSQGVWQVEVPATLQASLGGNQQFSSLDAVFDVESRVRSDAGQRYRKYILETIERLVTQEGKKFGALIMEPIILGAGGMLFCDPLFQRCLADVVRGNPQLFNRGRLTEPQPQTDLSWSGLPVIFDEVFTGLYRLGRKSSASFLGVNPDIAVNAKLLTGGLVPLCTTLASNEIFNAFTSPEKRDALLHGHSYTAHAVGCQVALDSLRTMNNMDEDGSWNDFKNDWKQPHAGDTARVWSVWSHKLLHNLSHAESVDGVFAIGSVLSISLKDAEGAGYTSTAAKGLQTRLAAGGPQFNVHSRVLGNVLYLMSSVTSKQETLRTIEGILREALL
What is the function of this protein?
Bifunctional enzyme; part of the cluster involved in the biosynthesis of biotin (also known as vitamin B8 or vitamin H), a water-soluble vitamin that functions as a prosthetic group of many carboxylases, such as acetyl-CoA carboxylase and pyruvate carboxylase (PubMed:20713166).  Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (PubMed:20713166).  Catalyzes also the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA) (PubMed:20713166).  It is the only animotransferase known to utilize SAM as an amino donor (By similarity).
What are the official names of this protein?
Bifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RELB_MYCTU
Sequence: MAVVPLGEVRNRLSEYVAEVELTHERITITRHGHPAAVLISADDLASIEETLEVLRTPGASEAIREGLADVAAGRFVSNDEIRNRYTAR
What is the function of this protein?
Induces its own promoter, in combination with RelE represses its own promoter.  Binds DNA in complex with toxin RelE but not alone.
What are the official names of this protein?
Antitoxin RelB.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: 1433B_PONAB
Sequence: MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negative regulator of osteogenesis.  Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.  Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
What are the official names of this protein?
14-3-3 protein beta/alpha.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: Y398_RICCN
Sequence: MFKKYIFILILFIASIARAEIIEVDSLNKIKQDFKENYNKNYVPQDLLVVTVLDEFLFKSLVPIVTQLDKDIYLTTLTPLLRNINKNSKTIYIKQLILTNDSYKKELQESDFPNFVNEISNSKIPIIAVNDGFTGNFNNIPKFEIWFADYLKKNFDIDFSNSFPNNNYIIFNNLDSFANTYPVFYKGILTSNNISEAEMMLNFLIQMNFIPKCFIMISSSIELLSSMELQLSSYSSNILFIGYHYNNKNTPKNKDVAYYTKLINDLISQINKLKRNNPPLKNNNAKGKNPYDTNK
What are the official names of this protein?
Uncharacterized protein RC0398.
Protein: MFNF_METJA
Sequence: MKIMILGIDIGGANTKITEIEGDNYKIHHIYFPMWKKKDELEDLLKNYNDNVDYVALVMTAELADCYKTKKEGVEDIIDKVEKAFNCPVYVFDVNGNFLTSEEAKKNYLDVSASNWNATAKFVAEFIKDSCILVDMGSTTTDIIPIKDKEVLAEKTDLDRLMNNQLVYVGTLRTPVSFLANKIEFRGKLTNLSSEYFAITADISLILNKITEEDYTCDTPDGAGKDFESCLTRLVRVLCADREMVKDDELIDFANKLYNKLLELIRENVDTIAKRYNLNDVVITGLGEEILKDALDEYNIISIKETYGKDVSLATPSFAVAKLLQKQLDK
What is the function of this protein?
Catalyzes the condensation between 5-(aminomethyl)-3-furanmethanol diphosphate (F1-PP) and gamma-glutamyltyramine to produce APMF-Glu.
What are the official names of this protein?
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase, 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase, APMF-Glu synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnF family.
Protein: URK_STRE4
Sequence: MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYKDQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQEPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1817_PECCP
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGSNPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDANMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLDEDAVMDAALEAGADDVVTYDDGAIDVFTPWETFGNVKDALDAAGLKAESAEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISDEVAELL
What are the official names of this protein?
Probable transcriptional regulatory protein PC1_1817.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y363_RICPR
Sequence: MQHAPDLVHSKDLTFVLRLDNEDILRKLFYLEAKRNNFSVEINEEWTLKINFPSKILELYKLLINNFYLKNFAKEELQKELYKELFPNCQIPFEQLIEEVSFFENFIECLKEFYIKKSLAQSIMFLLVSKYIEEHDVAKSLFKSESFKKVSELEKFKPYYDINKCDEVDNYVFNCILNDVKGPYIKNLSSSILDLVNHCQPDCEIVSIEILGNSAVLV
What are the official names of this protein?
Uncharacterized protein RP363.
Protein: A47_VACCA
Sequence: MGNKNIKPSKENRLSILSKDKMDSFKRGSFREKSRATIQRFSSLRREHIKVDHPDKFLELKRGIYEIIQKSSSIDVDKRTKLMSNIKTMMINPFMIEGLMTSLENLDPDNKMSYSSVMILGEFDIINISDNEAAFEFINSLLKSLLLEYSISNDLLYAHINALEYIIKNTFNVPERQLILRGQYLTPIFSDLLKYAGLTIKSNILMWNKQFIKPVSDLYTSIRLLHCVTESYKVIGMG
What are the official names of this protein?
Protein A47.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus A47 protein family.
Protein: DTD_ECO57
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.