PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_BACTN
Sequence: MNFELTSAYKPTGDQPEAIAQLTEGVLQGVPAQTLLGVTGSGKTFTIANVIANINKPTLILSHNKTLAAQLYSEFKGFFPNNAVEYYVSYYDYYQPEAYLPNSDTYIEKDLAINDEIDKLRLAATSSLLSGRKDVVVVSSVSCIYGMGNPSDFYKNVIEIERGRMLDRNVFLRRLVDSLYVRNDIDLNRGNFRVKGDTVDIFLAYSDTLLRVTFWGDEIDGIEEVDPITGVTTAPFEAYKIYPANLFMTTKEATLRAIHEIEDDLTKQVAFFESIGKEYEAKRLYERVTYDMEMIRELGHCSGIENYSRYFDGRAAGTRPYCLLDFFPDDFLLVIDESHVSVPQVRAMYGGDRARKINLVEYGFRLPAAMDNRPLKFEEFEEMTKQVIYVSATPAEYELIQSEGIVVEQVIRPTGLLDPVIEVRPSLNQIDDLMEEIQLRIEKEERVLVTTLTKRMAEELTEYLLNNNVRCNYIHSDVDTLERVKIMDDLRQGVYDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRSHRSLTQTAGRAARNVNGKVIMYADKITDSMRLTIDETNRRREKQLAYNEANGITPQQIKKARNLSVFGSPGSEADELLKEKHAYVEPSSPNIAADPIVQYMSKAQMEKSIERTRKLMQEAAKKLEFIEAAQYRNELLKLEDLMKEKWG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_HELMO
Sequence: MPRRLWPFGQTKTSADEQALSEQIDPHRIPKHIAIIMDGNGRWAKRRGLPRVAGHRAGVESLRRVLEVCEDYNIAYLTVYAFSTENWKRPADEVNALFDLLVEYLHRELNTLHSKGVRIRAIGKIEDLPGGPRRELEKAIAKTANNTRLVLNVALNYGGRFEIVEAVKSIARLAAEGKVNPDQIDEKYMSQYLYTADVPDPDLLIRPSGELRLSNFLLWQSAYTEIWVTPTLWPDFGRKEMVQAIVDYQGRDRRFGGVKV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: PSB_META3
Sequence: MIANNDQYKEYMKGTTTVGIVCNDGIVLATDKRATMGNLIADKEAKKLYKIDDYMAMTIAGSVGDAQSLVRIISAEANLYKLRTGNNIPPHSCAMLLSNVLHGSRHFPFLIQLIIGGYDTIHGAKLFSLDAVGGLNEETSFTATGSGSPTAFGVLEEEYKKDMTINKGKLLAIKSLTAAMKRDAFSGNGISLAVIDKNGVKIYSDEEIEELSNILYK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_STRPG
Sequence: MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIENQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_RICFE
Sequence: MYRYKITIEYLGTNLAGWQRQAGVISVQQILEEAIYKFSGEQVILFGSGRTDAGVHAIGQVAHFDLSKHLEPHKIITAINYFARPYAVGVWNCELASNNFHARFSATSRHYIYRIINRPYPSVIDLNRAWWISSPLDVLTMQKAAAYLLGKHDFTSFRASSCQSKSPIKTLTELNIIKEDEEIKLYLSAPSFLHHMVRNIVGSLVLVGKNVWQAEQIKDVLEAKDRKAAGPTAPASGLYFVKTEY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MANBL_HUMAN
Sequence: MASDLDFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPIPKSHEAEAEPSEPRSAEVTRKPKAAVPSVNKRPKKETKKKR
What are the official names of this protein?
Protein MANBAL.
What is the protein family that this protein belongs to?
Belongs to the UPF0239 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MQO_HELPY
Sequence: MSMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSIETNYTPEKAKKVRLSAYKTRQYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKEIFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYRKDWSTMNFAKLSENFVEEALKLKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLGCLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNKCWLKGISLELLKMDLNKDVFKIAFDLMSDKEIRNYVFKNMVFELPIIGKRKFLKDAQKIIPSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHKGITFNMTPSPGATSCLQNALVDSQEIAAYLGESFELERFYKDLSPEELEN
What is the function of this protein?
Catalyzes oxidation of malate to oxaloacetate in the citric acid cycle.  Donates electrons to quinones of the electron transfer chain.
What are the official names of this protein?
Malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NODL_RHIME
Sequence: MTRTQKEKMLAGEMYNAADPEIQADLLAAGAWLKRYNSTLGDSAEQWHLFLREGLGEVGPGAVIRPPFHCDYGFNISIGAHAYMNFNCVILDVAKVTIGDGTAIGPAVQIYTADHPDDPEQRQAGLQLGRPVRIGKHVWIGGGAIILPGVTIGDHAVVGAGSVVTRDVPPGAKVMGSPARVRG
What is the function of this protein?
Acetyltransferase implicated in the O-acetylation of Nod factors.
What are the official names of this protein?
Nodulation protein L.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: MURA_PSEPW
Sequence: MDKLIITGGARLDGEIRISGAKNAALPILAATLLADGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLAVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAKIEVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFINAMGGNVQGAGTDTITIDGVERLHSASYRVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLEKLKEAGADLTTGEDWIELNMHGKRPKAVNLRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAHIQVEGNTAIVTGVPALKGAPVMATDLRASASLVLSALVAEGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX10_DICDI
Sequence: MMLSKIINNISKSGLRNTTNSKNGGLLYFQNYYMKSSTTITRLNSGNNNYSNNNNNNNNIILNDKFLNKQQNDKKIIYNNIFEEKNQFLKRIYSTSTTTTSTTTTTNINENNIKNENNNENNNENSNNNNEQSIKSNQTKSKGFLRGPYMTLIKLPITVYVTLTAIAGYVAACPIGAFDWVVLSQVSIGTFLASCSANIHNQEIEVQHDRKMPRTKDRPLVIGTINRGKAWVGSIALLTLGFGTMAVTPSLFVPGTLAACNVILYCWYTDLKRVTPLNTWIGAFVGAIPPLIGSVAATGEFEAIGMLLATFMYIWQIPHFLALSQVLREQYRGAGYKMLSVTHEKKTVDRVSLAHALFGIPLPFIFDYFFNFNVHPITLTCMALSSASLALPFITKISPKRLYIISLISLPITLFLSCLLRQPFAYYTDDDDEDKDKDNQNQIENQDKK
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Probable protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SMAD6_MOUSE
Sequence: MFRSKRSGLVRRLWRSRVVPDREEGSGGGGGVDEDGSLGSRAEPAPRAREGGGCSRSEVRSVAPRRPRDAVGPRGAAIAGRRRRTGGLPRPVSESGAGAGGSPLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDSGDPQARQSPEPEEGGGPRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPPDQYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLLQHADAAHGPYDPHSVRISFAKGWGPCYSRQFITSCPCWLEILLNNHR
What is the function of this protein?
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators.  SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta (By similarity).  Acts as a mediator of TGF-beta and BMP anti-inflammatory activities.  Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of pro-inflammatory genes (PubMed:16951688).  Blocks the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding.  Binds to regulatory elements in target promoter regions (By similarity).
What are the official names of this protein?
Mothers against decapentaplegic homolog 6, MAD homolog 6, Mothers against DPP homolog 6, Mad homolog 7, SMAD family member 6, SMAD 6, Smad6.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB_VIBCH
Sequence: MAKLNAYFGEFGGQFVPQILVPALDQLEQAFIDAQQDDAFRAEFMSLLQEYAGRPTALTLTQNITKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKHEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMRLMGATVIPVHSGSATLKDACNEALRDWSASYETAHYLLGTAAGPHPFPTIVREFQRIIGEETKNQILAREGRLPDAVIACVGGGSNAIGMFADFIEEESVRLIGIEPAGKGIHTHQHGAPLKHGKTGIFFGMKAPLMQDEHGQVEESYSVSAGLDFPSVGPQHAYLNAIGRAEYESITDDEALDAFQALARNEGIIPALESSHALAHAIKMAYAEPDKEQLLVVNLSGRGDKDIFTVHKLLEDKGAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PHO13_ORYSJ
Sequence: MVKFSKQFEGQLVPEWKDAFVDYWQLKKDIKRLQAAEAEAAGVAATTPLSQCQAPVAAAHWVMRLPFLHPHGHHHKEHGAIQVHRKLASGGGGGGGAVAGEVYETELVDGGAGFADGEAARAFFARLDEQLNKVNRFYERKEAEFVERGESLRRQLQILAELRAAVVAEQQRDGRRRRCGNGGDSSPPDTEDPSVSCSILHGDQSLRGTSEQEQEGQEKLTKDMIARSPDEGDDDQLTIPQELGDSGRLGRPREEAANTRPRTTLPGGRAVTCQGRSVRINIPVTTPTRTVTAIRELLFDDMLSQSRRSGSANGTKCGDKLSINKRKVHQAEKMIRGALIELYKGLGYLKTYRSLNMMAFVKILKKFDKVTAKEAQSIYLKVVESSYFNVSDKVIRLMDDVDELFVRHFAEGDKRKAMKYLKPNQREESHTTTFFIGLFTGGFAALFIGYCIMAHIAGMYTQQSNKVYMATSYPVLSMFSLFFLHLFLYGCNIFMWRKTRINYTFIFEFTPTKELKYRDVFLICTTSMTIVIGVMFAHLTLIVKGYSSCAVQAIPGALLLVFLLILVCPFNILYRSCRYHFLTVIRNIILTPFYKVVMVDFFMADQLCSQVPLLRSLEYLACYYITSSYKTQDYGYCTRVKHFRDLAYAVSFLPYYWRAMQCARRWFDEGDINHIVNLGKYVSAMLAAGTKVAYENDNSAGWLSLVVIVSSLATIYQLYWDFVKDWGLLQFNSKNPWLRNDLILKQKYIYFLSMGLNLILRLAWLQTVIHPNIGSLDSRVTLFILAALEVIRRGHWNFYRLENEHLNNAGKFRAVKVVPLPFHEVEED
What is the function of this protein?
May transport inorganic phosphate (Pi).
What are the official names of this protein?
Phosphate transporter PHO1-3, Protein PHO1-3, OsPHO1;3.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBB_BRADI
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVSGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITDSWGGWSISGGTVTNPGIWSYEGVAGTHIVFSGLCFLAAIWHWVYWDLAIFSDDRTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQAVNPAWGAEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSNGLSENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDEEGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRSQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGTFQKVGDPTTRKQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CYB_ANTFL
Sequence: MINLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGVCLIIQILTGFFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIVVALAIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGLAFLFLILLLLALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIILLLHTANQRSMKFRPVSQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASMLYFLLILVLMPLAGLFENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LPLT1_CAEEL
Sequence: MRRNKTTYSLLQTILVACLLTVTPTFASNKPTTDESGTISHTICDGEAAELSCPAGKVISIVLGNYGRFSVAVCLPDNDIVPSNINCQNHKTKSILEKKCNGDSMCYFTVDKKTFTEDPCPNTPKYLEVKYNCVVPATTTTTTTTTSTTTTDSSLIVDEEEEAQKDALNSDVIKPVKKKEDVFCSATNRRGVNWQNTKSGTTSSAPCPEGSSGKQLWACTEEGQWLTEFPNSAGCESNWISSRNSVLSGVISSEDVSGLPEFLRNLGSETRRPMVGGDLPKVLHLLEKTVNVIAEESWAYQHLPLSNKGAVEVMNYMLRNQEIWGSWDVTKRKEFASRFILAAEKAMVASAKGMMTSAESNVIVQPAITVEISHKIKMSSQPTDYILFPSAALWNGQNVDNVNIPRDAILKINKDETQVFFSSFDNLGAQMTPSDVTVAIAGTDQTEVRKRRVVSRIVGASLIENGKERRVENLTQPVRITFYHKESSVRHLSNPTCVWWNHHELKWKPSGCKLSYHNKTMTSCDCTHLTHFAVLMDVRGHDLNEIDQTLLTLLTYVGCIISIICLLLTFFAYLIFSRNGGDRVFIHENLCLSLAIAEITFLAGITRTEDSLQCGIIAVALMYMFLSALTWMLLEGYHIHRMLTEVFPSDPRRFTYLLVGYIPPAIITLVAYLYNSDGFGTPDHCWLSTQNNFIWFFAGPACFIFCANSLVLVKTLCTVYQHTSGGYLPCRHDVDSGRSIRNWVKGSLALASLLGVTWIFGLFWVEDSRSIVMAYVFTISNSLQGLFIFLFHVVFAEKMRKDVGHWMYRRGCGGSSNSSPNHKRHNVQRDLMSPGVNSSTGSDFLYNTNDKYLTNSDTTNRLVYNGIMNHPNQMSVYQQHPHHQIYEQQPGTYDYATIAYGDMMPGHRVAAPPAYQRLAVAEGRYGSQHQLYQGWHHRPPPEFSPPPPPLSTGPPNSRHYGTGSSGRRPPSSKMSDDSAYSDGSSSMLTTEVTPQGQTVLRIDLNKPSMYCQDL
What is the function of this protein?
Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis.  Required for the alignment of the mitotic spindles and division planes.  May have a role in cell death events.  Required for normal defection and oocyte fertilization.  Involved in sperm function.  Operates in pharyngeal pumping during feeding.
What are the official names of this protein?
Latrophilin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCS2_METPP
Sequence: MALQDFTPSEPLTLGVELELQLLSTHDFDLAPQAEDLLRETAKHSGAWDIKPEITRSMIEIGSSIQRRHGPLREELRDMRNQLTRAARKLNIAIAGGGTHAYQHWSEQQIFPAERFRYISELYGYLAKQFTVFGQHVHVGCPDGDQALWLLHALSRYVPHFIALSASSPYVQGQDTGFDSARLNSVFAFPLSGRAPFVRSWEEFGGFFDKMTATGVVQSMKDFYWDIRPKPEFGTIELRVCDTPLSVDKAAALACYLQCICRQLREEKPFEPSEDDYLVYTFNRFQACRFGLDGEIVDPKTKQRSRLRDDILRTLTRLDEHALDLEALDATQLLRDSLFEGNDARWLRTQRAAMLPLPAVVEAAARRWGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: LIPA3_MOUSE
Sequence: MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQEALNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPVGESNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKDWDRSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKTNHVSKEEAGVPRGEGPAVPGDTPPPTPRSARLERMAQALALQAGSPEDGAPPRGSESTPDSLHKAPKRKSIKSSIGRLFGKKEKGRMGPPGRESVSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC
What is the function of this protein?
May regulate the disassembly of focal adhesions.  May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
What are the official names of this protein?
Liprin-alpha-3, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3, PTPRF-interacting protein alpha-3.
What is the protein family that this protein belongs to?
Belongs to the liprin family. Liprin-alpha subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Also detected in epididymosome.
Protein: RL28_CITBB
Sequence: MSRICEICGKGPSFGNNVSHANNKTSKIWRPNLQKIKAVKNGTVRSIKVCTRCIRSGHVTKAL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RNY_BACP2
Sequence: MSPTMFTIISILLSLICLVVGYFVRKTIAEAKISGARNMAEQIVEDAKRDAEALKKEALLEAKDEIHSFRVEAEQEVRERRNELQRQENRLLQKEENLDRKDESLDKRESLLEKRDHSLNERQQHIEEMESKVDDMIRLQKAELERISSLTRDEAKQIILDQVENELSHDIAVMTKESENRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQDGRIHPARIEEMVEKSRREVDDYIREMGEQTTFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSIEVAHLAGLMASELGEDAKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINSIASHHGDQEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEDISESYEGVEKSFAIQAGREVRIMVKPDSINDLEAHRLARDIRKRIEDELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ATPB_CHLVU
Sequence: MSVSTETKSSGRITQIIGPVLDVSFPAGKMPNIYNALTVGGKNEAGQEISVTCEVQQLLGDHCVRAVAMSATDGLMRGMEVLDSGKPLNVPVGAATLGRIFNVLGEPVDNLGPVNTKDQLPIHRSAPAFVDLDTKLSIFESGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINESNISESKVALVYGQMNEPPGARMRVGLTALTMAEFFRDINKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGGLQERITSTKDGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRNLASKGIYPAVDPLDSTSTMLQPWIVGDQHYQCAQNVKQTLQRYKELQDIIAILGLDELSEEDRLIVARARKIERFLSQPFFVAEVFTGSPGKYVSLAETIQGFNLILSGELDDLPEQAFYLVGNLDEAVSKAATLS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HSLU_XANOM
Sequence: MPNPDTSTMTPREIVQELDRHIVGQHDAKRAVAIALRNRWRRMQLPEELRNEVMPKNILMIGPTGVGKTEIARRLATLANAPFVKVEATRFTEVGYVGKDVEQIIRDLADTSVKLYREQAKVRVRNQAEERAEDCILDALLPRRATGIGFDPEAARNEPSSQENDTRIKFRRMLRNGELDEREIELEVAVNASMDIMTPPGMEEMGQQLRQMFSNLGSGKSQKRKLTIKAARPLLIEEEAGKLVNEDDVRTAAIKACEQHGIVFIDEIDKVAKRGEAGSNGGDVSREGVQRDLLPLVEGSNVSTKYGTVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELTALTKADFVRILTEPKAALIKQYEALLQTEGVSLTFAQDAVDRLAEIAAQVNERQENIGARRLHTVLERLLDVLSYEAPDRDGQSVTVDAAYVDAQLGELVQDPDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP69_CAEEL
Sequence: MRSQLLFSTHRLARCFGHRCSIFATTSHENALISTQKSIISMQTRAIHLTSFKFIRARHTDDKQEKNQNEGEDNQKGENKTTDQQDGPKKIDPSVIRKLRIYVLAVAGLSFVTSFIMLSQMFTGDRNSADGLTNEDFTRPGIPMKTFIDKYLKHGEVQRIVFVPNNSRAIAILHRGAVIDGKAASEASVIVEYPQNAQQFWADVRRAEGEIGIGLTEGVQIDLYQGMTTVKMIQLIIGVVILAWLGTQYGRLLRKRLLENQAKKGKN
What are the official names of this protein?
Uncharacterized protein B0495.9.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVA_BARHE
Sequence: MIGKLKGILEHIFDDHIIVNVQGVGYVVFISNRLRPSLPALGESLSLFIETHVREEAIRLFGFIAKAEQEWFCLLQNVPGVGAKVALAILGTLSPDELAQAIALNDIAMISRAPGVGKKVSERIVSELKSKALPFSEKVIHSAPLPHLEVTNQPTNDALSALIKLGFERDQAARALALAVNALEGETVSSALLIRHSLKLLSPPT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYGB_ACIAD
Sequence: MSKHTVLFELGCEELPPKSLKTLRDALQAETVKGLKDAGLAFASIEAYAAPRRLALKIVDVDGAQADTQKRFDGPAVQAAYDAEGKPTKALEGFMRGQGITADQVSTFQAGKVEKVCYLKDVKGQTLDALLPQILQTALDNLPIAKRMRSAASRTEFVRPVKWVVLLKDDQIIEATIQDHQAGNVTYGHRFHAPEAVTLAHANDYLAALEKAYVVANFEKRQATIQEQVKKLADEVNATAIVPADLLDEVTSLVEWPVALRANFEERFLAVPQEALITTMQDNQKYFCLINSEGKLQPYFITVSNIESKDPTQIIEGNEKVVRPRLSDAEFFFLQDQKQPLASRKEKLANMVFQAQLGTLWDKSTRIAKLAVALSPITGANPADAEKAALLAKCDLTSELVGEFPELQGIAGTYYARIEGENTEVSEALGEQYLPKFAGDVLPKTKTGTTIALADRLDTLVGIFGIGQAPTGSKDPFALRRSAIGILRLIIENELDVTIEELVNLALQGYGDIVKDHDKTLADAVAFLEGRYRAKYEDQGVAVDVLQAVQALAPKSPLDFDKRVNAVNHFRALPEAAALAAANKRVANILAKEAAPEGSVVEANLVEDAEKALFAELQAVTPAVEPLLAAKDYTAALSKLAALRAPIDAFFDGVMVMADDADLKANRLRLLAQLRHLFTVVADVSVLQG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.