PharMolix/UniProtQA huggingface dataset:
Protein: BIOF_CYAP4
Sequence: MDSHPYAWIEAALETVKRAHWYRSVQTIEGRPGAEVELAGQRVLNFASNDYLGLAGDQRLIRAAIQATEQLGTGSTGSRLLTGHRELHRQLERAIAQLKQTEDALVFSSGYLANLGTIAALVGPRDLILSDQYNHSSLKKGASLSGAKVLDYPHLDMGGLAELLQTHRSNYRRCLILTDTVFSMEGDVCPLPQLLAITTAHNAMVLVDEAHATGVLGATGAGAVEHWGCTDQTLIQVGTLSKALGSLGGYVAGTAVLIDFLRNRCPGWIYTTALSPADTAAALAAIAVVQSEPQRRIQLHENVQGVQAQLQNLPQLQEPRGRFRLLPSQSAILAVQMPDPATALEVGNALKQAGIFAPVIRPPTVPTSRLRLSLMATHTPDHCQRLGVAITTALARSLS
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: Y2263_ARCFU
Sequence: MFSLKVESEEGFCKIRLFPEHPEFSVGGYGRDDILVFKGAPVSLSAIQKMLEREFGDVIVNFRENSIEIEMQRMDCSLVIEDVASAIKEMMESAAKDLDKIEEVIKESLEKYLRRVGGDNGN
What are the official names of this protein?
Uncharacterized protein AF_2263.
Protein: PSTB_BORBU
Sequence: MIKEKDTPKNEVIIETENLNLFYTDFKALNKINMKILKNSITALIGPSGCGKSTFLRTLNRMNDLVEGIKIEGNVIYEGKNIYSNNFDILELRRKIGMVFQTPNPFLMSIYDNISYGPKIHGTKDKKKLDEIVEQSLKKSALWNEVKDKLHTNALSLSGGQQQRLCIARTLAIEPNVILMDEPTSALDPISTGKIEELIINLKESYTIIIVTHNMQQAGRISDRTAFFLNGCIEEESSTDELFFNPKNTKTEEYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EMAL5_MOUSE
Sequence: MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFFRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNSCEEGFATGGRDGCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGAYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSRYLQTNDGSGKRLLYKMPGGKEVTSKEEIKGMHWASWTCVAGLEVNGIWPKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERTPGTSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGKKGYVGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGMVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIRFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKRQTIPSVEVEKISWATWTSVLGLCCEGIWPVIGEVTEVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEVESHREKKYCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFGVKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASIGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSSLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCVHMPH
What is the function of this protein?
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 5, EMAP-5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HEM1_SALPA
Sequence: MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ISPG_VIBC1
Sequence: MQHESPIIRRKSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVEATVAQIRALEKVGADIVRVSVPTMDAAEAFKLIKQQVSVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVDCARDKNIPIRIGVNGGSLEKDLQMKYGEPTPEALVESAMRHVDHLDRLNFDQFKVSVKASDVFLAVDSYRLLAKQIDQPLHLGITEAGGARAGAVKSSVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVINTVNALEERLEDIITPMDVSIIGCVVNGPGEAEVSHLGLAGSNKKSAFYEDGKRQKERFDNDDLVNQLEAKIRAKASVLDQANRIDIKQED
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TFP11_HUMAN
Sequence: MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQSQQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK
What is the function of this protein?
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.  Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS).  In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.  May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
What are the official names of this protein?
Tuftelin-interacting protein 11, Septin and tuftelin-interacting protein 1, STIP-1.
What is the protein family that this protein belongs to?
Belongs to the TFP11/STIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles.
Protein: DGTL1_SHEB2
Sequence: MTSSVWQERRHGEDKQRRNDHRSPYQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRLTHSLEVSQIGTGIAAQLRRKYPQHKQLLCSMSLLESLCLAHDIGHPPFGHGGEVALNYMMRDHGGFEGNGQTFRILSKLEPYTLDFGMNLCRRTMLGILKYPAPHSKLFVAGEHNEITNHRQLKPSQWPPVKGIFDDDNDIFAWVLEPLSEADRSRFTSTQQGSHPALHHYPHLRTQFKSFDCSIMELADDIAYAVHDLEDAIVMGIVTASQWHQDVAPTLTNSGDTWIRQELADIGNKLFSHEHHLRKDAIGTLVNGFVTAIVISEDDVFEEPLLRFNATLEPEFAIALNVLKQLVYKYVIRKPEIQMLEYKGQQIVMGLFEAFASDPERLLPLNTQERWRESEQQGLNSHRVLADYISGMTDEFAGRLYQQLFSPKAGSNVELSKEM
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: REXO4_NEUCR
Sequence: MAPELSSNWKKLQEKLKAPQPTKSAPISQEAAFKQAISKKSISSETLKRKAEESQQQQQASNPSKKPKRQKSQTQSQPSSQKPTEEKMGGNVQSKPTTSSSPNSTLPSLHLWADEQGISSESLAEAYNLGLRGTSSSSSSSHIPLLSTLPPAIPNAGLTLPGHSSSSPKSNKNGLPLPTDLPSSLTLSNGLTLDTSTTTDLALILQATKSNTLGKYLSIDCEMVGTGPSGATSVLARCSIVDFHGHQIYDSYVRPTAFVTDWRTHVSGISKRHMASARSFESVQATVAALLKGRILVGHDVKHDLEVLGFEHPHRDIRDTAKYSGFRKYGHGPKPSLRVLAKEVLGIEIHQGQHSSVEDARVAMLLFRKEKHGFDMENSNRYEEGQAKKGGNGGGGGGGKKKKGKK
What is the function of this protein?
Exoribonuclease involved in ribosome biosynthesis.  Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
RNA exonuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAX_I69A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFVSPKEAKKQLKKDLKSQEQCAGLPTKVSRRTSPALRILEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: CSST1_CONTC
Sequence: MQTAYWMMVMMMVWITAPLSEGGQLNDVIRGLVPDNLAPQLVLQSLDSRRHPHGIRQDGAQICIWKICPPSPWRRLGS
What is the function of this protein?
Moderately activates human somatostatin receptors (SSTR) with a preferential activation of SSTR1 and SSTR4.  In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter.  Four to five hours after injection, mice recover, even with the highest dose tested.  Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system.
What are the official names of this protein?
Consomatin Te1, ConSST Te1, Somatostatin-related peptide, SSRP.
What is the protein family that this protein belongs to?
Belongs to the conotoxin C superfamily. Consomatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_SPICI
Sequence: MIQQESRLKVADNSGAKEVLVIKNLGGSWRKFTNIGDIVVCTIKKVTPGGIVKKGQVVKAIIVRTKRGLKRSDGTQIQFSENAVVLIKDDKNPRGTRIFGPIAREVKDAGFVKIASLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TKTI1_BOVIN
Sequence: MQTLRRQAAWPCVPRGTLEVDFPPPLYSDDYLSQEGPRWTPAIKQATRWKYTPMGRDAAGQLWYTGLTNSDSREAWYTLPRAPDSPYREAYARWHGCYGHRERSLPSAYTQRLRETAWYDPIIPAQYTDPSTRWGSVLWKDRPIRGKEFAINRHRFGVEALWRASDYVRYLSAPQRPRYTAQNYRQWGLEPYCPATNQRPPPVYTPSH
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.  Located at the center of the tektin bundle where may function to recruit tektins or stabilize the bundle.
What are the official names of this protein?
Tektin bundle-interacting protein 1, Uncharacterized protein C19orf71 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SECA_HALHL
Sequence: MFSAIAKRVFGTRNDRALKRLRKRIEAINAHEPELQKLSDEQLQAKTDAFKARLAQGETLDDLLEEAFAVVREASRRVLGLRHFDVQLLGAMVLHDGNISEMKTGEGKTLVATLAVYLNALTGRGVHVVTVNDYLARRDAEWMGRLYRFLGMEVGVVVPRQPREEKVAAYQADITYGTNNEFGFDYLRDNMAFRKEDKVQRDLYYALVDEVDSILIDEARTPLIISGPAEQAGELYEAMSRLVPRLQAQKPEERPEENPELGPGDYYVDEKARQVYLTEGGHDRAEELLREEGLIGENDSLYDARNINVVHHLNAALRAHTLYERDVHYLIRDNQVVIVDEFTGRAMPGRRWSEGLHQAVEAKEGLPIQAENQTLASITFQNYFRLYDKLAGMTGTADTEAFEFQHIYGLEVLSIPTHRPMVRDDAHDLVYRTADEKYEAIIADIRDCVQRDQPVLVGTTSIEASERLSKALKDAGVEHNVLNAKHNESEAQIIADAGRPGTVTIATNMAGRGTDIVLGGNLDQELAELGEDPDPAEVERRKAEWQDRHDRVVNAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDSLLRIFASERMSGMLEKLGMQHGEAIESGMVSRVIENAQRKVEAHNFDMRKHLLEFDDVANDQRKVVYEQRNELLEADDVAETVDAIRQDVVEKVISEHIPPGSIDEQWDVPGLERTLKEEFGQELPIQRWLDDEDDLHEETLRERIQGEIEKAYRAKEAEAGASVVRHFEKAVMLQVLDKHWKEHLAAMDYLRQGVGLRGYAQRNPKQEFKKDAFAMFQEMLEGLKRDAVGVLLRVQVRAEEDVEAVEEQRRQEAERMQMRHAAPASAAAGAVAAGSGAAGAAAAEGDSAPTGGAQQQSAGGRGQETVAREGPKVGRNESCPCGSGKKYKHCCGKL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PXPA_STAAN
Sequence: MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQLKINHVKPHGALYQMGAKDREIANVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: MNMA_SYMTH
Sequence: MPAGRRYGRTRRATLYVTKEGGGRPVAKRVLMAMSGGVDSSVAAALLVEQGYEVIGVTMNTWTDDIPEEIQMNQHSGCCSLAAVEDARSVAHKLGIPYYVMNFQGQFARTVIDYFIEEYTRGRTPNPCIACNRYVKFSAFLEKAKQLECDYVATGHYAVIGQDDRFPGRWLLGKSADARKDQTYVLHNLTQEALAHTLFPVGHLQKSEVRALAAKYGFVTADKPDSQEICFVYDNDYGRFLKERAPEAIVPGPILNTRGEVIGQHQGLPLYTIGQRKGLGLTTPRPVYVVDLDVERNAVIVGEDEETYRGGLVASDLNWIAIPGLTFPRRCRAKIRRMAPEAECTIYPIGEDAVRVEFDRPQRAITPGQAVVFYDGDWVLGGGTIERAIN
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STA5A_BOVIN
Sequence: MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSSAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLNPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSSHLEDYNGMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVSASADSAGSNATYMDQAPSPAVCPQPHYNMYPQNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLEPSLPPPTGLFTPGRGSLS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.  Binds to the GAS element and activates PRL-induced transcription.  Regulates the expression of milk proteins during lactation (By similarity).
What are the official names of this protein?
Signal transducer and activator of transcription 5A, Mammary gland factor.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: PPAC_STRP8
Sequence: MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTTHVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_VIBVU
Sequence: MQHNSLIARFAQGNLVLQILVGIILGISLALVSPSSAESVGMLGSLFVGALKAIAPILVFILVAASIANQKKNQHTHMRPIIAMYLAGTFFAALTAVVLSFMFPTTLTLVTGAEGANPPQGILEVIKTLLFKLVDNPVNALMSANYIGILAWGVGLGLALHHASDTTKAVFEDLSHSVSHIVRFIIRLAPFGIFGLVASTFATTGFDALAGYAHLLVVLLSAMAIIALIVNPAMVYVKTKQNPYPLVFQCLRESGVTAFFTRSSAANIPVNMALCEKLKLDEDTYSVSIPLGATINMAGAAITITTLTLAAVHTMGIEVDLMTAILLSVVAAVSACGASGVAGGSLLLIPLACGLFGISNDIAMQVVAVGFIIGVIQDSAETALNSSTDVVFTAAVCESEAQKAKG
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_VEREI
Sequence: MIGQWNNGTGRRKSSVARVFLKKGSGKITINGKDIQSYFGRETSIMIARQPLALTNHVETFDIRINVYGGGESGQAGAARHGITRALIDYDAALKPALSQAGFVTRDAREVERKKVGLHSARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: UBP13_XENTR
Sequence: MAEDLGELLVPYMPTIRVPKSGDRVYKTECAFSYDSPESDGGLYVCMSTFLGFGREHVERHYRKTGQSVYMHLKRHIRLKATGASGGAFPKRINGRLFLDLENNTEMNTEDYEYEDEAKLVIFPDHFEIALPNIEELPALVTIACDAVLNSKSPYRKLDQESWEEELQVSKFANNLVQIDNGVKIPPSGWKCSKCDLQENLWLNLTDGSIMCGRWFCSGSGGNGHALEHHKQMGYPLAVRLGSITPDGADVYSFDEEEAVIDPHLAKHLAHFGIDMLQMQGSENGVLDNEVKPRVNEWEVIQETGLKLKPMFGSGYTGIKNLGNSSYLTTVMQVIFSIPEFQRAYVGNLTRIFDYAPLDPTQDFSTQMAKLGHGLLSGQFSKPPMKSELIEQVMKEEHKPQPKGINTRMFKALMSKGHTEFSSNRQQDAEEFFLHFINLVERNSIGAENPSDVFRFLVEERTQCCQSRKVRYTERVDYIMQLPVPMETATNKEELIAYDLKRREAESAKRPPPELVRAKIPFSACLQAFTEPENVPDFWSSALQAKSAGVKTSRFASFPEYLVVQIKKFTFGLDWVPKKLDVSIDMPDLLDINHLRATGLKSGEEELPDIAPPIIIPDDPNGRMAESLLSGSGSNVNSSFKGAQPLNLPFGKKEAKLLRYMERMVEKFGFKFSVRLSVEIDFAEPLIIPGCGTVTSTSSHGQNALLNQPPEEIVALICSMGFPRNHALQALRATNNNLERALDWMFSHPESEEGADNVSGCVDTENNPNGIITDSEQEGPRIKDGNGRYELFGIISHAGTSTMSGHYVCHIKKEGRWVIYNDHKVSASERPPKELGYIYFYHRISC
What is the function of this protein?
Deubiquitinase that mediates deubiquitination of target proteins and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 13, Deubiquitinating enzyme 13, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: NRDR_BURM9
Sequence: MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLDTIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y006_KLEP7
Sequence: MLILISPAKTLDYQSPLATTRYTQPELLEYSQQLIGIARKLSAPQIGKLMSISDKLADLNATRFHDWHPDFTPQNARQAILAFKGDVYTGLQAETLTEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDTITEKLNQALRDQGDDIVINLASDEYFKSVKTPKLQGQLIKPVFLDEKNGKFKVISFYAKKARGLMSRYIIENRLTQPEQLKAFNSEGYFFDADASEKGELVFKRHEQ
What are the official names of this protein?
UPF0246 protein KPN78578_00060.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: ATPA_STRM5
Sequence: MATTLNPSEISELIKNRIEKVKLAAESRNEGTVTSVSDGIVRIFGLADVMQGEMIELPNNSFALALNLERDSVGAVVLGGYEHLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGTDLTAPVERVAPGVIWRKSVDQPVQTGYKSVDSMIPIGRGQRELIIGDRQTGKTAMAIDAVINQKGTGIKCVYVAIGQKASTIANIVRKLEENGALAHTVVVAATASESAAMQYISAYSGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTEGKVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANTQGELINKVNATGGWDNDIEGAFKKGIAEFKTTGSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GCSPB_BACC0
Sequence: MKNQDQALIFEVSKEGRIGYSLPKLDVEEVKLEDVFESDYIRVEDAELPEVSELDIMRHYTALSNRNHGVDSGFYPLGSCTMKYNPKINESVARFAGFANIHPLQDEKTVQGAMELMYDLQEHLIEITGMDTVTLQPAAGAHGEWTGLMLIRAYHEANGDFNRTKVIVPDSAHGTNPASATVAGFETITVKSNEHGLVDLEDLKRVVNEETAALMLTNPNTLGLFEENILEMAEIVHNAGGKLYYDGANLNAVLSQARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKADLIPYLPKPILEKTENGYHFNYDRPEAIGRVKPFYGNFGINVRAYTYIRSMGPDGLRAVTEYAVLNANYMMRRLAPFYDLPFDRHCKHEFVLSGRRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDGFIDKMIQIAKEVEENPEVVQEAPHTTVIKRLDETMAARKPVLRYAKPAPVQV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: CH10_YEREN
Sequence: MKIRPLHDRVIVKRKEVESKSAGGIVLTGTAAGKSTRGEVLPVGNGRILDNGEIKPLDVKVGDIVIFNDGYGVKSEKIDHEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.