PharMolix/UniProtQA huggingface dataset:
Protein: SYP_LEIXX
Sequence: MPTRLTNYFLRTLREDPADAEVTSHRLLVRAGYIRRQAPGVFAWLPLGLRVKAKIERIIREELAAAGAHEVHFPALLPREPYEITGRWEEYGDALFHLKDRKGADYLLAPTHEEAFTLLVKDLYSSYKDLPLTIFQIQDKYRDEARPRAGLLRGREFTMKDAYSFDATDAGLDVSYQAQRDAYERIFARLGLDFVIVQADAGAMGGSRSEEFLHPTPIGEDTFVRSAGGYAANVEAFTTVAPPARPFEGLPSPEVHDTPNAPTIQALVEVANEQSPRPDGRVWTAADTLKNVVLALTHLDGTRELVVVGLPGDREVDLKRAEVAFAPAGVEAATEDDFAANPGLVKGYIGPWSAGGPVLGEEAATGLRFLVDLRVVDGSGWITGANLPGKHVFGLVAGRDFDWDGTVEVAEVKAGDPAPDGSGPVELARGMEIGHVFQLGRKYADALGLTVLDENGKLVTVTMGSYGIGVTRILAIIAEENNDDKGLVWPEAVAPFDVHVVAAGREQVAFDVAEQAVAQLEAVGLDVLYDDRPKVSPGVKFGDAELIGVPRVLVVGRGAAQGEVELWDRRGGNHTTLPLSEAVAALTTSS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_BORRA
Sequence: MSIRTIKDCDFSGKRALVRCDFNVPLREGNITDDTRIKAALPTIEYLKSQGARVVLMSHLGRPKGEKNLRYSLMPIARRLSELLGQDVKMLSDCIGDEVVTAVSCMQNGDVVLLENVRFYKEEEENSDAFAMQLSKSGDIFVNDAFGTAHRAHASTSGVASYLPAVGGFLMEREDEFLGKILKNPESPFVSIIGGSKVSSKIAVLESLLPKSNVMVIGGGMAYTFLKVEGYSIGKSLLENEYIDVASSFLKKAKELSVEVILPIDHVVASEFQEYSMPEYVDSVNIPDSKIGMDIGEKTLKKIEGVLSSAKTVIWNGPLGVFEFDSFAKGTAKVAEYVANCPGITVVGGGDSVAAVNKFNLSGKITHVSTGGGASLEYLEGKVLPGIKVLEV
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNAA_PROIN
Sequence: MAKRIVEPFRIKMVENIRIPSREEREVALKEAGYNPFLLPSSAVYIDLLTDSGTTRYDHHGSMITGDEAYAGSRNYYDLKDKVKEMFDYDYVIPAHQGRGAENMLFPVLLKVKQEQGGAKKPVFISNFHFDTTAAHVELNHCKAINIVTEKAYDSDTYDDWKGNFDIQKLKDNIAPEWCRKRCCHYFSITCNSAGGQPVSMANLKEVYEIAKHHNIFVVMDSARFCENAYFIKERDPKYKNATIKEIILDMYKYADALTMSAKKDPLLNIGGLVCIKNDEKIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLEEGAGEEYLHYRIGQVKYLGDRLREGGISIQYPTGGHAVFVDCKKLVPHIPGDQFPAQAVINALYLESGVRAVEIGSFLLGRDPETGKQKHADMEFMRLTIARRVYTNDHMDYIADALIGLKDKFATLKGLDFEYEPPVLRHFTARLKPIK
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RLMI_SERP5
Sequence: MTVRLFLAKGREKSLLRRHPWVFSGAVQRVEGKALSGETIDIHDAQGKWLARGAYSPESQIRARVWTFLPDEEINIEFFIRRLQQAQNWRDWVAKRDGLDGYRLIAGESDGMPGITIDRFQNFLVLQLLSAGAEYQRAALITALQHCYPECAIYDRSDVAVRKKEGLPLAQGQVVGDLPPALLPITEHGMKLLVDIQQGHKTGFYLDQRDSRLAARNYSAGRRVLNCFSYTGAFAVSALMGGCTQVISVDTSQAALDIAKQNVELNQLDLSKAEFVRDDVFQLLRAYRTQGEKFDLIIMDPPKFVENKNQLAGACRGYKDINMLALQLLNPGGILLSFSCSGLMPTDLFQKILADAAVDAGRDVQFIEQYRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKB14_HUMAN
Sequence: MRLFLWNAVLTLFVTSLIGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYKHDEL
What is the function of this protein?
PPIase which accelerates the folding of proteins during protein synthesis.  Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen.  May also target type VI and type X collagens.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP14, PPIase FKBP14, 22 kDa FK506-binding protein, 22 kDa FKBP, FKBP-22, FK506-binding protein 14, FKBP-14, Rotamase.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MATK_SYZCU
Sequence: MEEFKGYFELDRSRQHDFLYPLLFREYIYALAHDHGLNRSILFKNAGYDKKSSSIVVKRLITRMYQQNPLIFSANDSIQNPFFGHNKNLYSQIISEGFAVIVEIPFSFSLRLVSSLERKEIAKSHNLRSIHSIFPFLEDKFSHLDYVSDVLIPYHIHLEILVQTLRYWVKDASSLHLLRFFLHEYWNSLITPKKHITLFSKGNPRLFLFLYNSHICEYESTFLFLRNQSSHLRSTSSGIFFERIYFYVKIEHFAKVFFDNDFQCILWFFKDPFMHYVRYQGKSILGSKDTPLLMNKWKYYLVTLWQYHFYAWFQPGRIDINQLCKYSLDFLGYRSSVPLNSSVVRSQMLENSFLINNAMKKFETIVPIIPLIGSLSKANFCNTLGHPISKPTRADSSDSDIIDRFLRICRNLSHYHSGSSKKKSLYRVKYILRLSCVKTLARKHKRTVRTFFKRLGSEFLEEFLTEEEVVLSLIFPRTYSTSRRLYRGQIWYLDITSINDLVNYENDWLLDHGNVNYL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCAT2_DANRE
Sequence: MPPPHRVFALPRQQSLLLPAVINPFVHDLSLSTADITKCFLLGIILVPLRAIFLLLVLLVMWPVSVIITFGQSLKGVVEPMTGWRRFLHRRVMTFLGRMYFFGMGFKVVVKGKKASTLEAPILAVAPHSSFFDAIACIESGLPSTVSRIESLEAPIFGRFLRCVQPVLVSRTDPDSRRNTIIEIERRAKSGGHWPQVLIFPEGTCTNRSCLITFKQGGFVPGVPVQPVLIRYPNKLDTVTWTWQGPKSARLLLLTLCQLCTTVEVEFLPPQVPTEMEKKCPLKFAQSVRAVMAKSLKLPVTDHTYEDCRLMIAAGELTLPMEAGLVEFTKISRKLELKWDNVKKELESFANIACSCKGGRITVEEFASFLKLPISPALQQLFALFDRNGDGTIDFREYVIGVTVLCRPANNEEVIQTAFKLFDIDEDNCITQEEFSSLLRSALGVCDLDVHSLFREIDADGSGHITYDEFRSFALNHPEYAKLFTTYIELQRYQGLQGDETDFDSAFSHCCTAAYDEYQEDSASDKKDD
What is the function of this protein?
Exhibits both acyltransferase and acetyltransferase activities (By similarity).  Activity is calcium-dependent (By similarity).  Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (By similarity).  Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (By similarity).
What are the official names of this protein?
Lysophosphatidylcholine acyltransferase 2, LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-AGP acyltransferase 11, 1-AGPAT 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkenylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acyltransferase-like 1.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Lipid droplet.
Protein: TIG_SALA4
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGEDFTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADAEDRVTIDFTGSVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFVINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMERELKGAVRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVSEKATSFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EXO84_ASPFU
Sequence: MESRGLTLRSRTRRARPQISAPKPISGPLPPNSKSTDSGQGNNVSQAVSRERIPTNGATSDLVKRRYSTRYNQAPEFDASAPPVPGLPAAASKYGGLGPPEASKKPSSDSSGPPQVDLNALRDPSLPVDRSNLLANATEEEIEEYQNNLRKVRNRTSTDLQQNVYQNRTQFIKISKEAEKLKGEMRTLRTLMAELTTALGQTAIGNAPNPMSPTADDWVPKRNANRSSVANLESMWNVQLQTLWKTVEGSQKFLPVAPGRHIVMETGQWVELDSATWKPRRPVHIVLLNDHLLVAAKKRKRVDASNHRGPVPTKLVAEECWPLQDVDMIDLGANMGTGAAREEAEERGIANAINVRVGSKTFTYRHDKRDSSDKGELLATFRKAVEDLRRTLRSESDTAIKPTDGFGYAGVKHSVSQKLDLNASDASRDKPEVRIDVDGKQQNLRWVDGQVDELDIDIALQRFEEAVSGIERLRKLARGLKGNSYAQQIINSKVDERAARLASVLSRALADTHSFLNATKTNVTWLTRLGFEDQAREAYLKARSDVISKRVRACVFEGDLPLYIFQVSYVYFTLIKNTINIYQQCFPAVLTSACIKWAKHHLDGFNALLTRQLSSVQRGTTVWQKCIDIVHEHADSLTEVGVDFVDLVAKGLDLHDNGGEKPQMTRSESLISGLADAARDHAF
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis.  Also involved in assembly of the spliceosome (By similarity).
What are the official names of this protein?
Exocyst complex component exo84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of EXO84 requires actin cables (By similarity).
Protein: MINC_BACHK
Sequence: MEEKKQQNVTIKGTKDGITLHLDDCCSFSELLKELDEKLSTHYYDGDGRSLIEVHVKVGNRYLTEVQQEEIRTLIRNKKNLVVDSIESDVITKEEAIAWKEETEIVPISKIVRSGQVLHVKGNLLLIGDVNPGGTVIAGGNIFVVGSLRGIAHAGYYGDSDAVIAASVMNPMQLRISDVAMRAPEEKEDGAEAAECAYINENNHIVVDRLQLLTHLRPNLTKLERGIV
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ILVD_PSYIN
Sequence: MPQYRSKTSTHGRNMAGARALWRATGVKDDDFGKPIIAIANSFTQFVPGHVHLKDMGQLVAGAVEAAGGIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADAIVCISNCDKITPGMLMAALRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMVMGPDKNVSDEDLAKVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADREQLFLEAGERIVDITKRHYEQDDYSVLPRAIACREAFENAMALDIAMGGSTNTILHLLACAQEAELDYTVADMDEMSRRIPQLCKVAPSTPLYHMEDVHRAGGVMAILGELDRAGLLNSDIPTILSPTMKEQLAKYDIMQTDDPKIIDFYRAGPAGIRTVKPFSQSCRWDTVDNDRAAGCVRSLEHAFSTEGGLAVLFGNMAVDGAVVKTAGVDNDNLTFTGPAKIYESQDTAVAAILGGKVVEGDVVVIRYEGPQGGPGMQEMLYPTSYLKSMGLGKKCALVTDGRFSGGTSGLSIGHASPEAAAGGVIGLIEDGDIIDINIPTRTMDLKVSDEILAERRIAMDIHGWKPVSRERHVSTALKVYALMATSADKGAIRDISKLK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GLME_SHIDS
Sequence: MELRNKKLTHDEFMTERQQVLKTWETGKNVENFEDGVKYQQAIPEHKRFSLALLKADKEGKTLSQPRAGVALMDEHIELLKTLQEECDLLPSTIDAYTRLNRYEEAAVGIKKSIEAGTSKLNGLPVVNHGVAACRRLTETLQKPLQIRHGTPDARLLAKISMASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLMGMYEEHGIRINREPFGPLTGTLIPPFISHSIAIIEGLLALEQSVKSITVGYGQVGSLTQDVAAIQSLRELAHEYFQSYGYTDYELSTVFHQWMGGFPEDESKAFAIISWGAAVAGMSGATKVITKSPHEAWGIPTAAANIQGLKASRQMLNMVNEQKFPPCPAVELEIELIKSEVRAVLNKVFELGNGDIARGTVLAFEAGVLEAGAVPLPKDILDLHHDYVAERARCEGRQPTFQMVVDDINAVSHSKLIGRP
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase epsilon subunit, Glutamate mutase E chain, Glutamate mutase large subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmE subunit family.
Protein: MTNN_PSET1
Sequence: MNVGIIGAMEPEVKILREAMQNPQTLTKAGFTFYTGELAGNTVTLVQSGIGKVASTIATTLLIDNFAPDCVINTGSAGGFDPSLNVGDVVISSEVRHHDVDVTAFGYEIGQVPQMPAGFAAHPKLVAAAEQTIAQISDVKTLVGLICTGDIFMCDPIRIEKARSDFPTMLAVEMEGASIAQTCHTLNTPFVVIRSMSDIAGKESPQSFEEYLETASINSSKMVVALLEKLTAVSL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: CMOB_SULDN
Sequence: MNINEIRKERQKWMQWKNIAPLREVIEHLGDVTCSVELGDVVTIKGKPLKNIEDTARLMMPWRKGPFEVFGTYIDSEWRSNIKYNLLRKHFNLKDRRVADIGCNNGYYLFRMQEDAPKLLVGFDPSPLFKTQFDFINRFVKSDIVYELLGVEHLEFYEDKFDTIFCLGVLYHRSDPVSMLKSLYKGLDKEGEVILDTFYIEGDEEICLSPASSYSKIPNIYFVPTISALKNWCLRAGFSSFEVLETSLTSSDEQRKTSWIEGESLEDFLDKNDNTKTVEGYPAPSRVYVRLKKGIK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: LEXA_FRAAA
Sequence: MTSQGRGTRRGGARGNVRAFPENPADAAGLTPRQRKVLEVIRAEVERRGYPPSVREIGEAVGLTSTSSVAHQLKVLEEKGYLRRDPNRPRAMEVLSPDRPRRKADSGAAAVVSTFPGAAAAPAGVGGEGSAAYVPVLGRIAAGGPILAEQAIEDVFPLPKEIVGEGTLFLLRVVGESMINAAICDGDWVVVRQQPVADNGEIVAAMIDGEATVKRLRVRDGKIWLHPENPTFSDIPGEEATILGRIVAVLRRI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: VATA_ARCFU
Sequence: MEVKEAGYVGEIYRISGPLVVAEGLKARMYDLCKVGEEGLMGEVVGLVGQKVLIQVYEDTEGVKPGDKVENTGMPLSVELGPGLIRNIYDGVQRPLPVLKEVSGDFIGRGIEAPGLDRKAKWEFKPLVKKGEKVKPGEIIGTVQETEVVEQKILVPPNVKEGVIAEIYEGSFTVEDTIAVLEDGTELKLYHKWPVRIPRPYVEKLPPVVPLITGQRILDTFFPVAKGGTAAIPGPFGSGKTVTQHQLAKWSDAQIVVYIGCGERGNEMTEVLEEFPELEDPRTGKPLMERTVLVANTSNMPVAAREASVYTGITIAEYFRDMGYDVAIQADSTSRWAEAMREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLAGNIGSVTVVGAVSPPGGDFSEPVTQNTLRIVKVFWALDAKLAARRHFPAINWLQSYSLYVDTLKDWFAENVSEEWNELRRWAMEVLQEEANLQEIVQLVGSDALPESQRVLLEVARIIREVYLIQYAYHPVDTYCSVQKQYDMLKAIKQINDWFYQALEAGKTIDEIAGVEGLEEFARAKFEEDYKPAMEAALEKIRKNLLGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PER66_MAIZE
Sequence: MAASVSASCLNRLSSLAVVLVALASAASAQLSSTFYDRSCPNALSTIRSGVNSAVRQEPRVGASLLRLHFHDCFVRGCDASLLLNDTSGEQSQGPNLTLNPRGFVVVNSIKAQVESVCPGIVSCADILAVAARDGVVALGGPSWTVLLGRRDSTASFAGQTSDLPPPTSSLGQLLSAYNKKNLNPTDMVALSGAHTIGQAQCSSFNDHIYNDTNINSAFAASLRANCPRAGSTALAPLDTTTPNAFDNAYYTNLLSQKGLLHSDQELFNSGSTDSTVRSFASSTSAFNSAFATAMVKMGNLSPQTGTQGQIRRSCWKVNS
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 66, Plasma membrane-bound peroxidase 3-2, pmPOX3-2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y765_XYLFA
Sequence: MSLHVTLRFTVALAAGLLFGFGLALSEMINPIRVLSFLNVASGHWNPSLLFVLGSALAVAFPGMALQRRLKRPLLDECFHLPSKKVIDRRIVFGSAIFGTGWGLTGLCPGPAIASLSTGLGPVLLFVAAMAAGMIIHDRIVVRCLS
What are the official names of this protein?
UPF0394 membrane protein XF_0765.
What is the protein family that this protein belongs to?
Belongs to the UPF0394 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RKD3_PYRCJ
Sequence: MDILLEEVRKVFGNTDEGKLAERLIVAYRQRGARGAREVLKKYLEELGVDVADIES
What is the function of this protein?
Part of an actin-like archaeal cytoskeleton.
What are the official names of this protein?
Arcadin-3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Forms cell-spanning helical structures.
Protein: DAPB_DECAR
Sequence: MSATRIGVVGAGGRMGRMLIEATLKDDRLVLGAAFDVPGSPALGKTAGELVGLPCDVVVTDDVAAGLKNIDCLIDFTRPQGTLVHLELCRKAGVGMVIGTTGFEADGKAVIAEAAKDIPVVFAPNMAVGVNVAFKLLETAARILNQGYDIEIVEAHHRLKVDAPSGTALRMGEVVASALGRDLEECAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVMFCGIGERVEITHKASSRMPYALGSLRAARFMAGHKSGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BACAC
Sequence: MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVGIVSPQVIDEINIYQATKQAMLDAIANLSCTPEYLLIDAMKLPAPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGVLEEHRKSFAPIKDMIKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX61_PANIM
Sequence: LVKCRGTSDCGRPCQQQTGCPNSKCINRMCKCYGC
What is the function of this protein?
Potently and reversibly inhibits the insect voltage-gated Shaker (Sh) potassium channel (isoform alpha (B)), the mammalian voltage-gated potassium channels Kv1. 2/KCNA2 (IC(50)=0. 44 nM), and the calcium-activated potassium channel KCa2. 3/KCNN3 (Kd=330 nM) (PubMed:9001397, PubMed:10931199, PubMed:11527975).  Its effect on Kv1. 3/KCNA3 is controversial, since this channel is voltage-independently inhibited in PubMed:9464266, but is not affected in PubMed:10931199.  Furthermore, this toxin competes with apamin (a small conductance calcium-activated potassium channel inhibitor) for binding to rat brain synaptosomes.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.1, PiTX-K-gamma, Potassium channel-blocking toxin 1, Pi-1, Pi1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGH_ECOSE
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RL27_BRUC2
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVLAGNIIVRQRGTKWHPGANVGLGKDHTIFATVNGSVSFRTKANGRTYVSVNPIAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SMYD5_CHICK
Sequence: MAAAAGDVRGAALGARPGLGAAAAAAAAAEARFISSAKGKGLFATRSIRKGEAVFVEKPVVSSQFLWNALYNYRACDHCLRALETAEENAQRLLGRSSLVLPHPEQCSIRKDLHQQCPRCQVTYCSAECRQAALEQYHQVLCLGPSRDDPTHPLNKLQEAWRNMHYPPETSSIMLMARMVATVKQAKDKDWWIKAFSQFCSKTANEEEEIAHKLLGDKFKGQLELLRLLFTEALYDEQLSRWFTPEGFRSLFALVGTNGQGIGTSSLSQWVHACDALDLPMLQREELDAFIDQLYKDIEKESGEFLNCEGSGLYMLQSCCNHSCIPNAETSFPDNNFLLYLTALEDIEAGEEICISYLDCCQRERSRHSRNKILRENYLFTCSCPKCLAQADDPDVTSDEEEEAEGETDDAELEDEMTDV
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3) which represents a specific tag for epigenetic transcriptional repression.
What are the official names of this protein?
Histone-lysine N-trimethyltransferase SMYD5, SET and MYND domain-containing protein 5, [histone H4]-lysine20 N-trimethyltransferase SMYD5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: C97D2_HUMAN
Sequence: MHGAPRLTFPCASEYLWHAREKAYQDHRRKVQSAQPLVDTRAPLTFRHLHLKLKRLKLEEERLSVIERDNRLLLEKVASVMRTRGQTDSKNNSKHRRK
What are the official names of this protein?
Uncharacterized protein CFAP97D2, CFAP97 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the CFAP97 family.
Protein: RL10_PROM1
Sequence: MGRTLESKKQIVKKIEDLLDNSEMALVLDYKGLSTKEMSDLRSRLQQSDGVCKVTKNTLMRQAIKGKNSWTGLDSLLTGTNAFVLIKGDVGSAVKAVQAFQKETQKSETKGGLFEGKLLSQDEIKAIAKLPSKEALMGQIAGALNSITSKIAIGINEVPSGLARSLKQHSESGES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.