PharMolix/UniProtQA huggingface dataset:
Protein: CTAA_STAAR
Sequence: MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLCHGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFLLLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKPLRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMAFIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFHALFITYLFGMTTYFIMLMLRSVRSDKQ
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KTR3_YEAST
Sequence: MSVHHKKKLMPKSALLIRKYQKGIRSSFIGLIIVLSFLFFMSGSRSPEVPIAQGTSVSRVASKDYLMPFTDKSQGVIHPVDDGKKEKGVMVTLARNSDLWNLVKSIRHVEDRFNNRYHYDWVFLNDQPFSDEFKRVTSALVSGKAKYGTIPKDHWSIPSWIDTEKFDEKRLAMGKLDIPYGSSVPYRHMCRFQSGFIWRHPLLEEYEWFWRVDTDITLFCDIQYDIFKFLKVNNKKYGFILSVSEYERTIPTLWETTKKFIKKNPKFLHKNNLMKFISNDDGDTYNMCHFWTNFEIGSLDFFRSDAYREYFDYLDSSGGFFYERWGDAPVHSIAASLFLDKSEIHFFDGLGFHHPDFTSCPIEQKIRLQNKCICEPSKDVTWTPDYFCTRKYFSAGNYKLPPGI
What is the function of this protein?
Possible glycosyltransferase that transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
What are the official names of this protein?
Probable mannosyltransferase KTR3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: EPCAM_CHICK
Sequence: MELLRGAALLLLLCAAACAQDSCTCTKNKRVTNCRLIDNVCHCNSIGSSVPVNCEILTSKCLLMKAEMANTKSGRREKPKDALQDTDGLYDPECENNGLFKAKQCNGTTCWCVNTAGVRRTDKHDTDLKCNQLVRTTWIIIEMRHAERKTPLNAESLTRYLKDTITSRYMLDGRYISGVVYENPTITIDLKQNSSDKTPGDVDITDVAYYFEKDVKDDSIFLNNKLNMNIDNEELKFDNMMVYYVDEVPPEFSMKSLTAGVIAVIVIVVLAIVAGIIGLVLSRRRKGKYVKAEMKEMNEMHRGLNA
What are the official names of this protein?
Epithelial cell adhesion molecule, Ep-CAM, Tumor-associated calcium signal transducer 1.
What is the protein family that this protein belongs to?
Belongs to the EPCAM family.
What are the subcellular locations of this protein?
Lateral cell membrane; Single-pass type I membrane protein.
Protein: RNH2_MYCBP
Sequence: MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPLVVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPSAEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGGDAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYSFINVRRVASGSNTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_SALPB
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_BRUAB
Sequence: MTKDIAQVMAEVGRKAKAAAAPLSIATSEQKNKALNAAADAILEARADILEANRLDLANAEKNGMAASFVDRLTLNEARIDAIAEGIRAIATLPDPVGEVIAEWDRPNGLHIERVRTPLGVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSAHSSAAIHKALVKGLEAANLPADAIQIVPVTDRAAVGEMLKGLGGAIDVIVPRGGKSLVARVQSEARVPVFAHLEGICHLYIDKSADLDMARRIALDAKMRRTGICGAAETLLVDRAVASTHLAPILGDLAAGGCEIRGSAEVLALYPAAKPATEEDWSTEYLDAIISVALVDGISGAIDHINRYSSHHTEAIVAEDAQTVARFFNEIDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGSGQVRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBIX_SHIB3
Sequence: MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQSGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDKNIQSLKSRYGENEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: RS7_SINFN
Sequence: MSRRHRAEKREINPDPKFGDLVVTKFMNAIMLDGKKSVAESIVYGAFEAVQSKLKQEPVAVFHSALDNIAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIAAARKRNETTMVDRLCGELMDAANNRGSAVKKREDTHKMADANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: THIC_BACAC
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIIKSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DFRA_GERHY
Sequence: MEEDSPATVCVTGAAGFIGSWLVMRLLERGYVVHATVRDPGDLKKVKHLLELPKAQTNLKLWKADLTQEGSFDEAIQGCHGVFHLATPMDFESKDPENEIIKPTIEGVLSIIRSCVKAKTVKKLVFTSSAGTVNGQEKQLHVYDESHWSDLDFIYSKKMTAWMYFVSKTLAEKAAWDATKGNNISFISIIPTLVVGPFITSTFPPSLVTALSLITGNEAHYSIIKQGQYVHLDDLCECHIYLYENPKAKGRYICSSHDATIHQLAKIIKDKWPEYYIPTKFPGIDEELPIVSFSSKKLIDTGFEFKYNLEDMFKGAIDTCREKGLLPYSTIKNHINGNHVNGVHHYIKNNDDDHEKGLLCCSKEGQ
What is the function of this protein?
Bifunctional enzyme involved in flavonoid metabolism.
What are the official names of this protein?
Dihydroflavonol 4-reductase, DFR, Dihydrokaempferol 4-reductase, Flavanone 4-reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: RPOB_JASNU
Sequence: MLGDGNEGMSTIPGLNQIQFEGFCRFIDQGLTEELSKFPKIEDTDQEIEFQLFMERYQLVEPLRKERDAVYESLTYSSEFYVSAGLIWKTSRDMQEQTILIGNIPLMNSLGTSIVKGIYRIVINQILQSPGIYYRSELDHNEISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGSNLKEILDNVFYPEIFLSFLKDKERKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQTKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADHLIEQKFGMGTLDDMNHLKNKRIRSVADLLQDQLGLALVRLEDEVRETICGPIRHKWRTTPHPQNLVTSTPLTTTYESFFGSHPLSQVLDQTNPLTQIVHGRKWSYLDPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHAKIGHWGSLESPFYEISERSTGVQMLYLSPGRDEYYTVAAGNSLALNQDIQEEEVVPARYRQEFLTIAWEQVHFRSILPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRPEKCIVGTGLERQVALDSGALAIAEREGKIVSTDTEKILFSGNGDTLSIPLVMYQSSNKNTCMHQKPQVQRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLISERLVYEDIYTSFHIRKYEIQTAGTERITNEIPHLEAHLLRNLDKNGIVMLGSWVETGAILVGKLTPEVVKESPANRLVYDIVGIQVSTSKDTCLKLPIGGRGRVIDVRWIQKRGDNDNPETIRIYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLDRHYRIVPFDERYEQEASRKLVFSELYEASKQTTNPWVFEPEYPGKSRIFDGRSGNPFEQPILIGKPYILKLIHQVDDKIHGRSVGNYTHITQQPLRGRAKGGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQKIPGTTMIGGTIPNPEDAPESFRVLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS15_FRAT1
Sequence: MLTAQDKQKIIKENQLAESDTGSPEVQVALLTARINDLQGHFEAHKKDNHSRRGLLRLVSQRRKLLDYLHDKDVERYRSLIKKLNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: EUTC_ECOLU
Sequence: MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: XNI_ECO55
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: A312_LOXS4
Sequence: WIMGHMVNAVKQIPTSLDLGANALEMDVTFKNEEPTYTYHGVPCDAFRDCIRWEYFNVFAKTLREYTTPGFDKYREQLILLVFDLKTGDMNNAQARTAGVNTAKQLLQYYWNNDNNGGRAYVVLSIPDIAQHELIKGFKETLKKEGHENLLDKVGYDFSGPYLPRLPTLDETHEAFKKAGVEGHVWLSDGLTNFSPLGDMARLKEAIKSRDSANGFINKIYYWSVDKVSTVEKALKVGVDGIMTNHPDVIIGVLNENGFKDKYRLATYDDNPWETFGK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin Ls4SicTox-alphaIII1ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DPB2_CRYNJ
Sequence: MVNQMRSAIVKVFSTKHSLTLPAPALHYIEEVLIENEIPEDEWMVGLEFWAKEYLKAEDSSSLVSLQALKKAYENLQLGTTEDTQVADPSEVNVESHFSVVDSFDMPAMRYDPVRSGFVQSKAQPSVAGQASSRSAFLRERWAIIKEIILRNENFTPPAIGGHDRANYLKLTSIRNLLGRAGQLFLLFGMLARNEEGKLCLEDGESRVVLDMEDAVPGEGLFTEGCMVLIEGEYTVEETVRVLAMGHPPSERRNIARSLHGHVDFLGGGAVSLKEEQKYNPTVLANTQISFVILSDVWLDHPRTMPALRQMFEGYANTAEYRPMVFVLCGNFCQGGWEGQEGLKRYSRGFNSLAELLQSIPLLHSSHFVFVPGPSDPWSSTTLPRPSLPSAFTTRLSNRIPNARFVSNPCRLKYFGMEIVICREDLMGKMMRNLVVVKEGEEMNMKRYLVQTILDQAHLSPLPISVRPTLWEYDHALRLYPMPSAVVLADKYERYELTYEGCHVFNPGKFVGGIGEDGWEFEWSMYYPATGRSERSVLTME
What is the function of this protein?
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon subunit B, DNA polymerase II subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase epsilon subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3_RIPO1
Sequence: MGQKIHPIGFRLGITADHKSCWYADSKRYPETLQEDRQIRQYITKNLSNAGISDIRIERKADQVDLAIHTARPGVVVGRGGSGIEQLRLGLQQDLGGNRQIRINVIEVQRVDADAMLIAEYITQQLERRVSFRRVVRQAIQRAQRAEVKGIKIQVSGRLNGAEIARTEWVREGRVPLHTLRADIDYAYRTAQTIYGILGVKVWVFKGEIIPGQEEIPMPVPSQTPRRQRRRQQFEDRSGEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HUTI_STRCO
Sequence: MSSSTVITNIAALVTNDPSLGDHSPLGLVRDAAVVVEGDRVVWTGESSKAPATDNRVDADGRAVLPGFVDSHSHLLFAGDRTEEFNARMSGRPYSAGGIRTTVAATRAASDAELEAGLTRYLAEALRQGTTTFETKSGYGLTTADESRALRVAARHTDEVTFLGAHIVAPELADDPAAYVDLVTGEMLDACAPHARWIDVFCEKGAFDGDQARAILTAGKARGLHPRIHANQLSYGPGVRLAVELDAASADHCTHLTDADVDALANSRTVATLLPGAEFSTRAQWPDARRLIDAGATVALSTDCNPGSSFTSSVPFCIALAVRDMGMTPDEAVWSATAGGAAALRREDVGRLVPGAYADLTLLDAPSHVHLAYRPGVPLVAGVWRRGVRKV
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABPI_HUMAN
Sequence: MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.  FABP2 is probably involved in triglyceride-rich lipoprotein synthesis.  Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.  FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
What are the official names of this protein?
Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, I-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_OENOB
Sequence: MLDVIVLDDKQKELDNDDAKLVKKVLAFAFDFMQLKQNYEMSVNFVNDEKIHQINKEYRNTDRATDVISFALEESDRIHIDGVAEELGDLFISLDHAHAQAEEYLHSYNRELAYLAVHGFLHLLGYDHTRSQAAEDEMFGLQDKILEGYGLTK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_BURTA
Sequence: MSESNAASVRTVACLLGPTASGKTAAALALAARRPIEIVSVDSALVYRGMDIGTAKPTREERAAVPHHLIDIVDPADAYSAAGFRADALRVVAEIAARGRTPLLAGGTMLYYKALTQGLNDLPAADPDVRATLDAEAARDGWPALHARLASVDPATAARLAPNDAQRIQRALEVYLLTGRPMSALLAAPPRNDDAAAGLRFVPVALEPSDRAVLHARIAARFDAMLEAGFIDEVERLRRRDDLHLGLPSMRCVGYRQAWEYLEGVTDYRMMRDKGIFATRQLCKRQLTWLRAMPARIVVDCCAQDATARAVDALERVLDGRTPA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RLMH_DESVM
Sequence: MKSLRLLAVGKLKTPFWQQAAAHYLERLRHTWRVTETLVRDGDAALPPAKRNADEGARLLAALGPADIVVCMDERGKAYTSREFAALLDRLTENATAVPCFVIGGAYGLDDAVLKRATLRVCLGPMTFPHEMARVVLLEQLYRADCILRRSPYHH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E118_ADET1
Sequence: MRNWELSVSPSFLELCDQYVSLCESPSFSGPSCLNDMAPDDILGNCDLFAEAADALFPDCLLEEVEAASGLAFETNEEVEGFVFPDCPERPGQECRSCKQHREMSGDPSILCSLCYMRLTACFVYSPVSDVEDEEPTEGVAENSLKRQADSSLCSSSPKRFC
What are the official names of this protein?
Early E1A 18 kDa protein.
Protein: ANDF_EMEVA
Sequence: MTVPQLHYVPYDTPVEDVMRILEECGTLVIRNFLDQKTVQNVQNEVDDYVRNWNPGPKYNHDIKTVGSKTKQPSNLSLMSKTYRCEVLNHPWMHAICERMFGPTYGDYWFNGGSILHLEPGEHTQPIHQDHVFYHISKWRRPTDPDLTINFAMALTEFTVENGGTRVCPGSHLWENGHAPPAEEDMVPALMQPGDALILPGSMWHSAGANRSSEYRRGFAASFHPCHFTPIESHHHLPREMVEEMSPLVQKMLGFRTLNLHNNVKVWKAGEGNLEDATGLKSIAV
What is the function of this protein?
Dioxygenase; part of the gene cluster that mediates the biosynthesis of anditomin, a fungal meroterpenoid (PubMed:25216349).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase andM (PubMed:25216349).  DMOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHDMP) by the cytochrome P450 monooxygenase andK, which is further prenylated by the prenyltransferase andD to yield farnesyl-DHDMP (PubMed:25216349).  Further epoxidation by the FAD-dependent monooxygenase andE leads to epoxyfarnesyl-DHDMP (PubMed:25216349).  The next step involves the terpene cyclase andB that converts epoxyfarnesyl-DHDMP into preandiloid A through opening of the epoxide ring followed by the cyclization of the farnesyl moiety (PubMed:25216349).  Preandiloid A is in turn oxidized at the C-3 hydroxyl group to yield preandiloid B by the dehydrogenase andC (PubMed:25216349).  The dioxygenase andA is solely responsible for the dehydrogenation of preandiloid B leading to the enone preandiloid C, as well as for the intriguing structural rearrangement to generate the bicyclo[2. 2. 2]octane core, transforming preandiloid C into andiconin (PubMed:25216349).  FAD-binding monooxygenase andJ then produces andilesin D which is reduced by dehydrogenase andI to yield andilesin A (PubMed:25216349).  Action of acetyltransferase andG followed by a spontaneous acetate elimination leads then to andilesin B, which is in turn substrate of the short chain dehydrogenase andH to yield andilesin C (PubMed:25216349).  Finally, the dioxygenase andF catalyzes the transformation of andilesin C to anditomin (PubMed:25216349).
What are the official names of this protein?
Dioxygenase andF, Anditomin synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: DAPF_BRUSI
Sequence: MATKAAFARMNGLGNQIIVADMRGRADSITSAAAIRLASDSETAFDQIMAIHDPRTPGTDYYIAIINCDGTQAQACGNGTRCVVQALAAETGRHAFTFETRAGILTATEHDDGLISVDMGTPRFDWQDIPLAQAVADTRKIELQVGPADAPVLHSPSIASMGNPHAVFWVDKDVWSYELDKFGPLLENHPIFPERANISIAHVTSSDTIDLRTWERGAGLTRACGSAACAAAVSAARTGRTGRKVTVNVPGGPLLIEWRDDDHVMMTGPAEWEFSGTFDPATGEWSRDTQGLQGSGNADRGAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CAMJE
Sequence: MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNHDCFESVEAVNGYLNFRISKTFLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYPEQYYKGEYIVDLAKEAFEKFGKEFFSEENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYVSERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADHHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVDEIGSDALRYIFLSKKCDTHLEFDISDLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNLAANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMB_PASMU
Sequence: MSENIYGIHAVSAFLNNAPERLIEVYALKGRDDKRLQPLLNELHRLGITIQFVNRQTLDKKAEGEVHQGIMARVQPAKELNEADLDTLLQNQSNPLLLVLDGVTDPHNLGACLRTADAAGVCAVIVPKDKSAQLTAIARKVACGAAEVVPLIRVTNLARTLRELQQKHNIWVVGTAGEATNTLYQTQLTGGLALVMGAEGEGMRRLTREHCDQLISIPMAGSVSSLNVSVATGVCLFEIVRQRLA
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGB3_MEDSA
Sequence: MGFTDKQEALVNSSWESFKQNPGNSVLFYTIILEKAPAAKGMFSFLKDSAGVQDSPKLQSHAEKVFGMVRDSAAQLRATGGVVLGDATLGAIHIQKGVVDPHFAVVKEALLKTIKEVSGDKWSEELNTAWEVAYDALATAIKKAMV
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin-3, Leghemoglobin III.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.