PharMolix/UniProtQA huggingface dataset:
Protein: NADD_MYCA1
Sequence: MGGTFDPIHYGHLVAASEVADLFGLDQVVFVPSGQPWQKDRHVSAAEDRYLMTVIATASNPRFSVSRVDIDRAGPTYTRDTLRDLHALNPDSELFFITGADALASILSWQGWETLFELAHFVGVSRPGYELRREHITGVLGELPDDALTLVEIPALAISSTDCRQRAAHRRPLWYLMPDGVVQYVSKRRLYRAEPGPAVAVTETSLSTGDHP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RLMH_DESRM
Sequence: MIKISILCVGKLKEKYLAEGIKEYLKRLTPYAKVDISEVPDEPCPENAPMAIEEQVRQKEADKLAKKLRPGTFLVVLDLKGKMLSSEDMAGKIQDLALSGKSDLTFIIGGSIGLAPSLVERANLLLALSNLTFPHQLVRLLLMEQIYRWFKIIHNEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_METM7
Sequence: MQGVYPAIITPFKDGKVDYDGLQSNLDFLIENGVSGVIPVGTTGESPTLTPLEHEQVIEKVVEFVDGRVEVIAGTGSNSTSEALEFSQYAEDVGVDGVLLITPYYNKPSQEGLKRHFGEIANSINVPIVLYNVPSRTALNIEPYTIKYLFEEYSNITAIKEANPNLSQVSEVLDSCNIDVLSGNDELTLPIISLGGKGVVSVVANIAPKEFVQMVDFANAGKFDKAKEIHYKLFPLMKLMFIETNPIPIKTAMNMLGMPSGELRLPLCEMAESNKSKLQNALNNLGLLK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKF_VIBC3
Sequence: MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRANNAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNVFGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILDIQECVYGDLELDFIEETLFALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYLTYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFDLARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RNY_DESAP
Sequence: MLENTAIIIAITTGFVAFIGGYFLRKLLGEMKITSAEERARLVLEEAAKEAESKKREAVVEAKEEILKLRNEVERESRERRSELQRQERRLVQKEESLDRKLEALEKKEENLAKRETELAKMHEELKALHQKELQELERISGLSTEEARQILLQDVEKEIQQEAALLVKEIEGRAKEEADRRARNIISLAIQRCAADHVAESTVAVIPLPNEEMKGRIIGREGRNIRAFETLTGVDLIIDDTPEAVIVSGFDPIRRETARMALEKLISDGRIHPARIEEMVEKARKDMEVQIRDTGEQAAFDANVHGLHPDLIKLLGRLKYRTSYGQNVLKHSVEVAYLAGLMAAELRADEKLARRAGLLHDVGKAVDHEVEGPHVTIGVDLAKKYGESPEVLHAIAAHHGDEEPETVEAVLIQAADAISAARPGARRETLEAYVKRLTKLEDIANSFPGVEKAFAIQAGREIRIMVKPDKVDDLGAVRLVRDIARKIENELEYPGQIKVVIIRETRVVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AROA_CLOPE
Sequence: MKKVIITPSKLRGSVKIPPSKSMAHRAIICASLSKGESVISNIDFSEDIIATMEGMKSLGANIKVEKDKLIINGENILKDSNYKFIDCNESGSTLRFLVPISLIKDNRVNFIGRGNLGKRPLKTYYEIFEEQEIKYSYEEENLDLNIEGSLKGGEFKVKGNISSQFISGLLFTLPLLKDDSKIIITTELESKGYIDLTLDMIEKFGVTIKNNNYREFLIKGNQSYKPMNYKVEGDYSQAAFYFSAGALGSEINCLDLDLSSYQGDKECIEILEGMGARLIESQERSLSIIHGDLNGTIIDASQCPDIIPVLTVVAALSKGETRIINGERLRIKECDRLNAICTELNKLGADIKELKDGLIINGVKDLIGGEVYSHKDHRIAMSLAIASTRCKKEVIIKEPDCVKKSYPGFWEDFKSLGGILREE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCGRN_HUMAN
Sequence: MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA
What is the function of this protein?
(Microbial infection) Acts as an uncoating receptor for a panel of echoviruses including Echovirus 5, 6, 7, 9, 11, 13, 25 and 29.
What are the official names of this protein?
IgG receptor FcRn large subunit p51, FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane.
Protein: LOLD_BRUSU
Sequence: MAAEIILRLERIGRAYKEADRELIILNDADFTLRRGEMVALVAPSGAGKSTLLHTAGLLERPDSGDVVLDGRSCSKLSDDERTAVRRNDVGFVYQFHHLLPEFSALENVMLPQMIRGLSRKAAAERAQQLLEYMKIGKRASHRPAELSGGEQQRVAIARAVANAPLVLLADEPTGNLDPTTSSYVFGALEALVRQSGLAALIATHNHELARRMDRRVTLKDGRVVDL
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU4LC_SOYBN
Sequence: MIFEHALVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINLVTFSDFFDSRQLKGNIFSIFVIAIAAAEAAIGPAIVSSIYRNRKSTRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QUEF_CHRSD
Sequence: MSERDKTLEHAPLGRESAYPEHYDAGLLFPIPRQANRAPLGLDDAALPFEGEDEWHAFELSWLDAKGKPIVAVARFRLPADSPSLIESKSWKLYLNSFNQTRFDRREAVIDTLERDLAQAAGASVAVALFGVEDDALMPRALPGECLDDLDVSIEYYTPTPGLLEVGEEIVEETLHSHLLKSNCPVTGQPDWGSVLIRYRGPRLERDALLKYLISYRQHQDFHEHCVEHLFVDLMARARPERLLVMARYVRRGGLDISPWRGTPGERPPTPLRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F110C_HUMAN
Sequence: MRALAALSAPPNERLLPRDPAATRDPDAARPARRSAVERLAADRAKYVRGRPGTGRGVASEGSGPGAIKCPGNDPGPPARAPAPVARRAIARKPLRPDSLIIYRQKCEFVRGSGADGPRASLVKKLFQGPGKDKAPVPRTGDEGKAGNPETVPTTPGPAADPAIPETPAPAARSAAPSSVPAAPPGPEPRVVRRRGLQRSQSDLSSRYSAALAESDTFFQYCGLDPEVVEALGRENFTAGSDCVTLKVRSVSVATSGSGFSRHSGGDDEGLQEEELIEQVPSTTSVIERNARIIKWLYTCKKAKETPSQEQSRTRGSKPSR
What is the function of this protein?
May play a role in microtubule organization.  May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway.
What are the official names of this protein?
Protein FAM110C.
What is the protein family that this protein belongs to?
Belongs to the FAM110 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Nucleus. Note=Colocalizes with microtubules during interphase (PubMed:17499476). Detected at the mitotic spindle poles (PubMed:17499476). Colocalizes with AKT1 at the cell cortex (PubMed:19698782).
Protein: PER13_ARATH
Sequence: MITIALFLVLLYFHDQLGYSAAQLQFGFYSETCPSAESIVRDVVQQAVTNDPGKAAVLLRLQFHDCFVEGCDGSILIKHGGNDDERFAAGNAGVAGFDVIDEAKSELERFCPGVVSCADIVALAARDAIAEAKGPFYEVPTGRRDGLIANVDHAKNLPDVQDSINTLKSKFREKGLSDQDLVLLSAGAHTIGTTACFFVIPRLDAQDPTINPEFFQILRSKCPQGGDVNVRIPLDWDSQFVFDNQIFQNIKNGRGVILSDSVLYQDNNMKKIIDSYLETNQSSKANFAADFTKAMIKMGAIGVKIGAEGEIRRLCSATN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 13, Atperox P13.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDB2_OPICY
Sequence: MNRKLLLVFLVVAMLVMQPAEAGFWSKIKDFAKKAWNSPLANELKSKALNAAKNFVSEKIGATPSEAGQIPFDEFMDVLYS
What is the function of this protein?
At high concentrations, acts as pore former in cellular membranes and causes the leakage of the cells.  At submicromolar concentrations, degranulates granulocytes and has a weak hemolytic activity against human erythrocytes.  Also strongly inhibits the production of superoxide anions.  Has a strong antibacterial activity against Gram-negative bacteria but is less active against Gram-positive bacteria.  Also has antifungal activity.
What are the official names of this protein?
Probable antimicrobial peptide Con13.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: NUCMR_DICDI
Sequence: MDLDYSSDNSRLVADNQNNKTNTKNQSQLSTSSQIPQTSQSYQQQQQHNQQQQQQQQQKQNSRPSSPKTIQAKVNNNNNNNNNNNNNNNNNNNNGATISHPPTSQSNEDLSSSAEIHHDDSAQLNSNIFENLGFVIDITINLKRKMELVKIIKKNGGKSCYSCTKATHLITTKQGYLEKTQKVTQAISLGIPILVKEYVHYCAFKKELLGVENYLVSSLILNPTSTTLNSSQDLIEKPNEEEPQNGTINEQPIAMTIDNTLESNKPIETIQPSSLEKQEPKETELQTQQQPQTELKSELEPQQLQLIQEKDKNINNLSIDSNHMDTSKIEAGNNISNQTQSNIISSVVQTIEPLKECNKIDLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSNNKNKNNVDEAQEGLNINSVMDVHLTSSTSSTLSSSDNQDNELLRDEGTTPKSKKKFSQKKNHLLNLKKSYQDPEIIAHSRPRKSSGGVSLVEALSDHANYISNLDGFKYYARANKSSLNSNATTSGGNNRSIKLNEYKYDDEEEDEEDEDEEDEEEDEEEEEEEEEEEEDYDDEDLNDEESDEDDFDSDEDVSRFIKGKLLQKQQKIYKDLERFEHSRQQQHHHHQSSQVNSSKPRSRSHSRDYIESEIAKYLLNNSEKQIPLSPTKKRSLSNQFHQDGGNNTTDGNLFNNFSTNGGGNRTNIDDSIKQSILESPSSSSLKSSKSKKSKKPFLPPLSTLVHILVTFIILSAFFMSLPSN
What are the official names of this protein?
Nucleomorphin, Calmodulin-binding protein A, Calmodulin-binding protein CaM-BP38.
Protein: YIDC_BURVG
Sequence: MDIKRTVLWVIFFMSAVMLYDNWQRDHGRPSMFFPSATQTAPAAASGASGTGATTTAGEAPAAAAAGAAPATTAPAAQAQLVKFSTDVYDGEIDTRGGTLAKLTLKKQGDGKQPDLYITLFDHTAGHTYLARTGLLGGDFPNHNDVYTQLNPGATSLTGDQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIDNVGTAPVTPTVYMELVRDNTAVETPMFSHTFLGPAVYTDAKHFQKINFSDLDKNKADYVNSADNGWVAMVQHYFASAWIPQQGVKRDIYAEKIDPSLYRVGVKQPVAAIAPGQSADVQARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGVVGNWGWAIVLLTILIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWILWIHDLSQRDPFFILPVLMAVSMYVQTSLNPTPPDPVQAKMMKFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRKLGGVKKKPA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_PARP8
Sequence: MNANPKFISANAHVDEAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTESLQGLSSEYGRERAADPATAELRFPGLHRTPRRAQPGKNVSQMHYAKQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHPGQAFGATAFGPNGLQEITPEFVREEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLEWCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKTGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVRDYAAKEGMSDADALKKGMEVKAVEFIKSGAEIYQRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: LPXH_SALPB
Sequence: MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKVLDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHEGSMVKVTPDNVELIAFPL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PVK1_THEPT
Sequence: GSSGLISFPRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, ThePe-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMTB_PSEA7
Sequence: MAHLVWQDDLNTGIQVIDNQHKRIVEMINLLHDAQQGKEHAAIAEVIEELVDYTLSHFAFEETLMEDAGYQFSRAHKKIHELFIRRVSEYRVRFQAGEDVGDELKGLLSRWLFNHIRNDDAGYVDAVRHSMSELVKDKSEGGWLSRSMKRFFG
What is the function of this protein?
Oxygen-binding protein.  May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes.  The oxygen-binding site contains two iron atoms.
What are the official names of this protein?
Bacteriohemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: SCPB_BACC0
Sequence: MDRTEQKSIIEGLLFVSGDEGIYPEQIAKVLEIEGNEVIDILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIEIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: TIG_ZYMMO
Sequence: METVETLNEGLKRNYTLTITADEIRKRIDQEVAEAAPRVNLPGFRPGKVPAKLVNKMYGASLAQDALNKALQDGVQKLLSDKGEKPAMQPEIELTEGYELGKDAELKVKFEILPEVPEISFDDLKLERLTVEADNAVIDEKIKEFAEHQKSFDDSKKDHKAENGDLVVVDFVGKVDGEPFEGGTGSDMSVELGAGQFIPGFEEQLVGAKQGESRVLKVTFPEDYSVPYLKGKDAEFDVTVSDVRVPRKAEVNDDFAKSLGLESLDQLRDLMKGQIEQELNGLTRTYMKRKLLDQLADSYSFEVPSQMVEAEFNQIWRQLEHAASHEEDSEAALAEMEKERDEYRAIAERRVRLGLALSDIGAKNNVEVSQNEMNMLISQAAQRYNPADRQRFVEYLRQDPMMAAQLRAPLYEDKVVDILFEKANITDRAVTREELEAAIEAEEDSIGKHDHDHDHKEKASDKPKAKKAAAPKKKAAPKKKAAPKAEKKSSDE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SERC_YEAST
Sequence: MSLEREEPQHFGAGPAQMPTPVLQQAAKDLINFNDIGLGIGEISHRSKDATKVIEDSKKHLIELLNIPDTHEVFYLQGGGTTGFSSVATNLAAAYVGKHGKIAPAGYLVTGSWSQKSFEEAKRLHVPAEVIFNAKDYNNGKFGKIPDESLWEDKIKGKAFSYVYLCENETVHGVEWPELPKCLVNDPNIEIVADLSSDILSRKIDVSQYGVIMAGAQKNIGLAGLTLYIIKKSILKNISGASDETLHELGVPITPIAFDYPTVVKNNSAYNTIPIFTLHVMDLVFQHILKKGGVEAQQAENEEKAKILYEALDANSDFYNVPVDPKCRSKMNVVFTLKKDGLDDQFLKEAAARHLTGLKGHRSVGGFRASIYNALSVKAVQNLVDFIKEFAEKNA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, PSAT, Phosphohydroxythreonine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
Protein: MURG_CUPPJ
Sequence: MTQQRTLLVMAGGTGGHVFPGLAVAHALREQGWKVVWLGNRTGMEATLVPKHDIPMEFIQFGGLRGKGLVTKFLLPLNLLRAFWQSLGALRRVRPSVVLGMGGYITFPAGMMASLLGRPLVLHEQNSIAGLANKVLAKVADRVLCAFPDTLPDSEWTGNPVREELAHMAEPEARYDIRTGPLNVLVVGGSLGAAALNDVVPKAIAMLPEAQRPVVTHQAGAKQIDKLRANYAAAQVSAQTLPFIDDMAKAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNAEFLSKQGAALLVQQQELTADGLAKTIAGLNRPQLKEMARLARGLAKPEATRRVAEVCSQMARD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS11_RHOBA
Sequence: MAKTNKKKRIRRNVSNGVAHVHATFNNTTVTITDAKGDTLCWASAGTSGFKGSRKSTPFAGQCAAQQAAEKATKFGMRDVEVRVKGPGSGRESAITALQAAGLNVKLIEEVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AGOG_METKA
Sequence: MTVPTFLRKVTLREICVIEEYVDVQYRAIEALMDTLPSTDLVRLTVANALVSYQLSSSGEDWWREFSSYFRERRPRDIVREYARFLPRSRGNRRLIRQKLRRLHRAKAFLEELSWQDAKSYYRDMNRLRLDLARVLNADPESKTIVFTVKMFGYALRAITGRFRPYPFEIPIPVDARIERITRRITNDDPQLYWDSIARRTGIPPLHLDSILWVGTSRDPEVKRLLAKVLPKLIGELEMLGN
What is the function of this protein?
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
What are the official names of this protein?
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, AGOG, DNA-(apurinic or apyrimidinic site) lyase, AP lyase.
What is the protein family that this protein belongs to?
Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
Protein: UVRB_METBU
Sequence: MSGFELVSDYEPKGDQPEAIRKLSEGLNKGLKHQVLLGVTGSGKTFTVANVIQNVQKPTLVIAHNKTLAAQLFSEFREFFPNNAVEYFVSYYDYYQPEAYLPTTDTYIEKDSSVNEEIDRLRLSATKSLIERKDVIVVSSVSSIYNIGSPDEWRRMSVILRTGDEVGRSDLFAALINIHYERNDIESAKGSFRSKGDTIEVFPAQDNHGVRIELFGDEIDRISSFDPVTGKTIDEVKEDNSIVIYPAKHFVMPQEEMVKALGSIEKELEGQVAKLVSENRILESQRLTQRAKFDLEMIRELGYCSGIENYSRHFDGRKPGDPPSSLLEFFPDDFLLVIDESHVTIPQIRGMHNGDRARKEALINYGFRLPSAYDNRPLTYNEFHHKINQAIYVSATPADYELGISSAVVEQIIRPTGLVDPVVFIRPVENQIDDLIGEVNKVTEKGYRTLVTTLTKRMAEDLTEYLLEMGIRVRYMHSDIDTLERAEIIRDLRKGVFDVLVGINLLREGLDIPEVAFVAILDADKEGFLRSERSLIQTMGRASRNADGYVILYAGKVTGSIEAALRETNRRRQIQLAYNEKHGIVPQTIHKALQRELVETEYGEVVSEVLGVAEDLSDIEIADMVIELEAEMHLAAKNLEFERAAALRDNIKELRSTYSL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.