PharMolix/UniProtQA huggingface dataset:
Protein: ARP4_SCHPO
Sequence: MTSAFYGGDEVSAIVIDPGSKWTRIGFSGEDIPKCVLPSYCGEFSDGRRLFGEEYIYKSNPGMEIKNAIRNGWVENWDVTVDLWRYGLEQQLKTNPLEHPILITEPFDNPPENRVKTLETMFESLRCPATYLAKQETCAAFASGKGTACLVDIGAERSSVSAIYDGFVLQKGYQVQHFSGNAINDILAQTLRDKNFEVMPKYLVKSKNPVEIGQPANCELRPRDTTDSYHQFQVQRVYDEWKEECALISDVPFSSETTIAESEFEFPDGSRMMFGAERYQIPEHLFVPGSDEEMNEEPSKPIEQTENNEVSQQDSSVTNTSSRILGIPQLFQNCISECDVDIRASLLNNVIVCGGTSLMQGFSLRLQNELSKLYPGSRLKIHASGHVVERSYASWLGGSILSSLGTFHQLWISRQEYEEHGSDRLALIEKRCK
What is the function of this protein?
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Is required for NuA4 complex integrity.  Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
What are the official names of this protein?
Actin-related protein 4, Actin-like protein arp4, Actin-like protein 4, Altered polarity protein 5.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_MYCGE
Sequence: MVKIRLMRMGRVHYPLYRIVAVDSRVKRNGKYIALIGHLNPALKENKCKLDETVALDWLNKGAIPTDTVRSLFSESGLWKKFIESKNKKETSPKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ZKSC1_HUMAN
Sequence: MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFRRFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNLARRNLSRDNRQENYGSAFPQGGENRNENEESTSKAETSEDSASRGETTGRSQKEFGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGAFLKSCV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 1, Zinc finger protein 139, Zinc finger protein 36, Zinc finger protein KOX18.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPNA_PENRW
Sequence: MASTPKANVPKIDVSPLFGDNMEEKMKVARAIDAASRDTGFFYAVNHGVDVKRLSNKTREFHFSITDEEKWDLAIRAYNKEHQDQIRAGYYLSIPEKKAVESFCYLNPNFKPDHPLIQSKTPTHEVNVWPDEKKHPGFREFAEQYYWDVFGLSSALLRGYALALGKEEDFFSRHFKKEDALSSVVLIRYPYLNPYPPAAIKTAEDGTKLSFEWHEDVSLITVLYQSDVANLQVEMPQGYLDIEADDNAYLVNCGSYMAHITNNYYPAPIHRVKWVNEERQSLPFFVNLGFNDTVQPWDPSKEDGKTDQRPISYGDYLQNGLVSLINKNGQT
What is the function of this protein?
Isopenicillin N synthase; part of the gene cluster that mediates the biosynthesis of penicillin, the world's most important antibiotic (PubMed:1368505).  The first step of the pathway is performed by the trimodular NRPS acvA that produces the tripeptide N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine (LLD-ACV or ACV) via condensation of the 3 residues L-2-aminoadipate, L-cysteine and L-valine (PubMed:9266851, PubMed:9355751, PubMed:19686863, PubMed:21889568).  The precursor amino acids for penicillin biosynthesis are withdrawn from the vacuolar amino acid pool by the MFS-type transporter penV (PubMed:8416970, PubMed:22777282).  Each of the constituent amino acids of the tripeptide acv are activated as aminoacyl-adenylates with peptide bonds formed through the participation of amino acid thioester intermediates (PubMed:9266851, PubMed:21889568).  The tripeptide ACV is then cyclized to form isopenicillin N (IPN) by the isopenicillin N synthase ipnA that forms the beta-lactam nucleus (PubMed:1368505, PubMed:1369045, PubMed:1588566).  Finally, the alpha-aminoadipyl side chain is exchanged for phenylacetic acid by the isopenicillin N acyltransferase aatA to yield penicillin (PubMed:2120195, PubMed:2110531, PubMed:1368505).  This step occurs in the peroxisomal matrix and the penM and paaT transporters are involved in the isopenicillin N and phenylacetic acid import into the peroxisome, respectively (PubMed:23053082, PubMed:24480587).
What are the official names of this protein?
Isopenicillin N synthase, IPNS, Isopenicillin cyclase, Penicillin biosynthetis cluster protein ipnA.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS13_ENCCU
Sequence: MAKMHSSGKGRSGSVKPYATAFPTWLTKSVDEIKSDVIQMGNKGVPAPDIGTRLRDEYGIGKASDVLGESITRFLQRNGVVPKIPHDLESLVHRANTLRSHLNIYRKDNSAKYRLILVSSRMYRVARYYKRKMRIPGNWKPKLVELNK
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FBLN7_MOUSE
Sequence: MGPGSQRALFLLLLLLASPGARAFQSCLNKQQLLTTIRQLQQLLKGQETRFTEGIRNMKSRLAALQNTVNKMTPDAPPVSCPALEAPPDGKKFGSKYLVDHEVYFTCNPGFQLVGPSSVVCLANGSWTGEQPRCRDISECSSQPCHNGGTCVEGINHYRCICPPGKTGNRCQHQTQAAAPDGGEAGDPAFSRAPRCAQVEREQHCSCEAGFHLSSTTGGHSVCQDVNECEIYGQKGRPRLCMHACVNTPGSYRCTCPSGYRILADGKSCEDVDECAGPQHMCPRGTTCINTGGGFQCVNPECPEGSGNISYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSKLKTPITLFRMATASIPGHPGPNSLRFGIVGGNSRGHFVMQRSDRQTGELILTQTLEGPQTLEVDVDMSEYLERSFQANHVSKVTIFVSRYDF
What is the function of this protein?
An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
What are the official names of this protein?
Fibulin-7, FIBL-7, Protein TM14.
What is the protein family that this protein belongs to?
Belongs to the fibulin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS6_BURMS
Sequence: MRHYEIVFIVHPDQSEQVPAMIERYKSTITSHGGQIHRVEDWGRRQLAYMIEKLAKAHYVCMNIECDQTTLDELEHAFKFNDAVLRHLIVKMKKAETGPSPMMKEVQREEAKKAAAAQPTEAQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: 3MGH_WOLPP
Sequence: MNNTILPRNFYERPTLTVAGELLGKMLKFSNFSGIITEVEAYIGMDDPACHAARGYTNRTSVMFGTPGFSYVYFIYGMYYCLNIVTEAEGFPAAVLIRGLKLTEPLEANLGGPGILCKKLNITKEHNKQDLTISHEFCLYEYHLKPDYVCTPRIGISKGKEKFWRFKSCVLADMPKITLNNKY
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: Y1972_YERPP
Sequence: MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLFEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YPDSF_1972.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL31_SHEPA
Sequence: MKAGIHPDYAEITATCTCGNVIKINSTVGKDLHLDVCGACHPFYTGTQKVMDTGGRIDKFNKRFGALGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NAGZ_ECOLU
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSG_HALMA
Sequence: MTNTKQKINAVFLSALMVMSVFAAAVAFSGAAAAANRGAGFTYSTGPTDSNGGGNGDSVGQVGPGAVVFQGEEDLEDGGNFGSNTDIGQLQKVSGDNSGILLGNPIPQDQPTGSYTFDGNSGTDGVTLQTPRVTSVEVQNGGSGDVTGSTLQTSSSGPDAFVRADYNFQEAEDLEITVEDENGLEVTNEIVVQKTGLPTADRNNDNGASGSNGDFDVGWELDTTDIDEGQYTITVEGTEDLTFGDASETVTVNITSDQQASLNLDNDEVVQGENLQFNVENSPEGNYHVVLVESSEFRDGITADQASRIFRNVGDVQEVGLVDNTGPVSASTVASNVGSDQEVADVTRYAYGVVEIDGGSGVGSIETQFLDDSSVDVELYPASDSSNDGYASGGSHASSVTVRDTDGDGTDDSEDAIVTDLLETDDDQSFDVVEGEITLDSPSGAYITGSQIDVNGTANQGVDQVALYARDNNDYELIEIDGSNTVSVDGDDTFSEEDVVLSQGSKGGNSIVSLPGSYRIGVIDVQDADLDSDGTVDDTLTTSDFNSGVSGATALRVTDTALNGTFTTYNGQIASDDGQIDVDGQAPGKDNVIVAFVDSRGNAAAQVVSVDDDDSFSEEDIDITSLSEGTVTAHILSSGRDGEYGDTGTSSDSAFVNTIETGYAGGSSTGDQVREQILANTVDDTASDDLIVNEQFRLTDGLTTIESVSSPVEANGTLEVQGNTNRVPDDNTITVEILNSEDESVTVESTDEWGSDGQWSVNVDLSDVDIEPGNYTVEADDGDNTDRTSVTVVEAGSLEEEQPDTETPEPDTETPEPDTETPEPDTETPEPDTETPEPDTETEEATTEASGPGFTAAIALIALVAAALLAVRRDN
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
Cell surface glycoprotein, S-layer glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the halobacterial S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Cell membrane.
Protein: CSN9_DROME
Sequence: MKPSLAADEMFSEGPGYMEMDESGGATGMMMDHLPSNDKHVHADFYNDFDDLFDEDNWAKMKTDGKQ
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity.
What are the official names of this protein?
COP9 signalosome complex subunit 9 homolog.
What is the protein family that this protein belongs to?
Belongs to the CSN9 family.
Protein: CMOA_PSYIN
Sequence: MSKTDNIYSKRRAQIDGFSFDEQVVQVFPDMIKRSVPGYETIINSIGTITERCAVENSNLYDLGCSLGAATLSMRRGLNKAGCQIIAVDNSQQMVERCEQYIHAYKSDTPVQVLCDDICNIHIENASVVILNFTLQFLTPEKRLNLLTNIYNGLLPGGVLVLSEKFVFEDPLNHQLLNDLHLDFKRSQGYSELEISQKRASLDNVLIADTVEQHYLRLRKAGFKHNNLWYQYFNFGSIISIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: KGUA_SYNJB
Sequence: MRRSLSMPTSPTPVSSECTQQQGSLPAPTPRGRLVVLTGPSGVGKGTLVNQLRQRHPELYLSVSVTTRPPRPSEQEGVNYYFRSREEFLNLIEANELLEWAQYAGNFYGTPREIVFQKLNQGQDVLLEIELAGARQVRQQYPDAIRIFLCPPSLEELERRIRERGQDSEASIERRLEQARKELDAQDEFDYVIVNDNLEQALQELEALLYPPSPSSKEQQP
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZMP to dZDP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB8_MOUSE
Sequence: MDDLSEANGSFAISLLKILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGLSGNGDVHQSFQTLLAEINKTDTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLEELSFAKDTEGCRKHINDWVSEKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQEKKTVQMMFKHAKFKMGHVDEVNMQVLALPYAEEELSMVILLPDESTDLAVVEKALTYEKLRAWTNPETLTESQVQVFLPRLKLEESYDLETVLQNLGMTDAFEETRADFSGMTTKKNVPVSKVAHKCFVEVNEEGTEAAAATAVIRNARCCRTEPRFCADHPFLFFIWHHKTSSILFCGRFSSP
What is the function of this protein?
Has an important role in epithelial desmosome-mediated cell-cell adhesion.
What are the official names of this protein?
Serpin B8.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_CAMFF
Sequence: MQRYPTKQILVGNVKIGGDAPISVQSMTFAKTRDVKECLEQINRLYFAGCDIVRCAVFNKEDIVGLEQVKKESPLPIVADIHFNYSYAVAVSKFVDAIRINPGNIGGKDRIKAVVEACKERNIPIRIGVNSGSLEEQFENKYGRSVKGMVQSALYNIGLLEELEFTDIAVSLKSSDVYNTMQAYRELRPFTSYPFHLGVTEAGTTFHATIKSAIALGGLLLEGIGDTMRVSITGELEEEIKVARAILQDTGLQKSGLNIISCPTCGRLQSDLVSAIKIVEEKTKHIKEPLNVSVMGCVVNAIGEAKGADVAIAFGKGNGLVMRHGEVVARLKEHELVDRFLSEIDDEIKQRASNNG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ACADM_MOUSE
Sequence: MAAAFRRGCRVLRSVSHFECRTQHSKAAHKQEPGLGFSFELTEQQKEFQATARKFAREEIIPVAPEYDKSGEYPFPLIKRAWELGLINAHIPESCGGLGLGTFDACLITEELAYGCTGVQTAIEANSLGQMPVILAGNDQQKKKYLGRMTEQPMMCAYCVTEPSAGSDVAAIKTKAEKKGDEYVINGQKMWITNGGKANWYFLLARSNPDPKVPASKAFTGFIVEADTPGIHIGKKELNMGQRCSDTRGIAFEDVRVPKENVLIGEGAGFKIAMGAFDRTRPTVAAGAVGLAQRALDEATKYALDRKTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTAQIQRLIIAREHIEKYKN
What is the function of this protein?
Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:16121256).  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:16121256).  Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).  Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains (PubMed:16121256).
What are the official names of this protein?
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL2_STACT
Sequence: MALKHYKPITNGRRNMTSLDFAEITKTTPEKSLLQPLPKRAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGIPAKVDSIQYDPNRSANIALLVYADGEKRYIIAPKGLQVGQTIENGEEADIKTGNALPLANIPVGTTIHNIELKPGRGGQIARSAGASAQVLGKEGKYVLVRLRSGEVRMILSTCRATVGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: UT103_PEA
Sequence: FKGGGPYGQGVTRG
What are the official names of this protein?
Unknown protein from spot 103 of 2D-PAGE of thylakoid.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid.
Protein: RS5_XYLFT
Sequence: MAEERSQRSRDRSREEKIDDGMIEKLVAVNRVSKTVKGGRQFTFTALTIVGNGEGSVGFGYGKAREVPVAIQKSMEYARKRMSNVSLNNGTLWHPVKANHGAASVFMKPASEGTGVIAGGAMRAVLEAVGVKNVLAKAIGSRNPINLVRATLKGLEDMQSPTHIALKRGKNVRDFSHGS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NOP58_CRYNJ
Sequence: MLVLTETSVGFVVFKLSSDAKIDNKDLWKEFETPEGANKALKVQAIQRFTSTASAVEDLTAVQDGRLTDSLSRFLLDTVGGADDGEKKKKKKKIEEMLVVSDPKLAGTINKALSIPVLSDSSTQDLYRGIRQQLASLLGGVDQKDLNTMSLGLGHSLSRFKLKFSTDKVDTMVIQAIALLDDLDKEINIYAMRVKEWYGWHFPEMAKIIVDNIAFARVVKAMGFRTNAVTTDFSLLLPEDLEATLKSAAELSMGTEISDSDMTHIHSLCDQVISISEYRTQLSEYLRNRMQAIAPNLTALVGELVGARLISHAGSLMNLAKHPASTVQILGAEKALFRALKTKHDTPKYGLIYHASLIGQAPQKLKGKMARMVATKAALSIRVDALSDADSRSDVSAAEVGISNRVKLESRLRALEHQAGIQSVRKVVSANGQQGRQQPRFEMSGVTGSYNAATDNVPLNGDLLPTQPATEEVKEEKDEKKDKKDKKKKRKSEVAEAGDVTMDGDADLSMVAGETKEERRARKEAKKAAKAAKKAAEESGDGDKKSKKRRADEDEDSEKKKKKKKKDE
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NTPPA_DICT6
Sequence: MKKEIILASNSPRRIDLLKHMGVDFKVVSPNVEEEGNGEKRSPVEVVKKNAIMKVQKVAEDYRNAIIIGADTVVVIDGEIIGKPTNEKDARRILRKLRGRYHFVFSGVAVMETPEDKVLVSVVRSKVKMRDYSEEEIERYIATGEPMDKAGAYGIQGKGALLVEKIEGDYYNIVGLPLVRLNSLLNRLGYSLL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y698_STAAB
Sequence: MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIVSLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYGVTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPISLIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQSIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIHNYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDADDMVHVAKNQGRNKVMFNPIINL
What are the official names of this protein?
Uncharacterized membrane protein SAB0698c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRD_SHESA
Sequence: MFYKIAQKVMFQMDPERAHNLAIGSLKMTGNSPLNAFYAQNIAPAPVSFMGLTFPNPVGLAAGMDKDGESIDAFHAMGFGHVEVGTVTPRPQPGNDLPRLFRLKPAKAIINRMGFNNKGVDNLVKNLIAKKTDIMVGVNIGKNKDTPVEQGKDDYLICMDKVYPYAAYIAVNISSPNTPGLRSLQYGDLLDELLSALKTKQLELAEKHKKYVPIALKIAPDLTTEEIENIAQSLIKNKFDGAIATNTTLTRDGVSGLANANESGGLSGKPLTELSTKVIKQLATGLNGQIPIIGVGGINSAEDALAKFDAGATMVQIYSGFIYQGPKLIKEIVEAYRLK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEPA_PROM3
Sequence: MTDVPVSRLRNFCIIAHIDHGKSTLADRLLQDTGTVAGRDMQEQFLDNMDLERERGITIKLQAARMNYTAADGESYVLNLIDTPGHVDFSYEVSRSLQACEGALLVVDASQGVEAQTLANVYLALENDLEIIPVLNKIDLPGSDPERIKEEIEAIIGLDTSTAIACSAKTGLGVSEIMQAVVDRIPPPADTLDEPTRALIFDSYYDSYRGVIVYFRVISGRISTKDKVLLMASKKSYELDEIGVMSPDQCEVNELHAGEVGYLAASIKAVADARVGDTITLLNAPADEPLPGYTEAKPMVFCGLFPTDADQYPDLREALDKLQLSDAALKYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYKVNMIDGQMLMVDNPATLPDPQKRESIEEPYVRMEIYAPNEYNGTLMGLCQERRGEYIDMKYLTTERVTLIYELPLAEVVTDFFDQMKSRTKGYASMEYHLIGYRRNDLVRLDVLINAEKADPLTTIAHRDKAYSIGKGLVEKLKELIPRQQFKIPLQASIGSRIIASESISAMRKDVLAKCYGGDISRKKKLLKKQAKGKKRMKAMGKVDVPQEAFMAVLKLNQTS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DYR3_SALTM
Sequence: MLISLIAALAHNNLIGKDNLIPWHLPADLRHFKAVTLGKPVVMGRRTFESIGRPLPGRRNVVVSRNPQWQAEGVEVAPSLDAALALLTDCEEAMIIGGGQLYAEALPRADRLYLTYIDAQLNGDTHFPDYLSLGWQELERSTHPADDKNSYACEFVTLSRQR
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase type 3, Dihydrofolate reductase type III.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: VP3_BROAA
Sequence: IGDIWSGIQG
What are the official names of this protein?
Venom peptide 3, BaP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_ANADF
Sequence: MAEPNDVAAAGAAAIAASFEAYQEERARITRRARERFEKRDWAAGQADARERLDLRDRLVNACVGTVRAELGGAAHDHGLWRAMKELYEARVESRPDREIGQSFFNSVTRRVFVTVGVDPAIEFLAADGPAVREGPVPVYARYRREVSTEALLRTVLRACAFAAPYEDLERDARIAAIELDSHLRELDDGQPIEALELVKAVFYRGKGAYLVGRLRRGRYTTPLVLALVHGERGVVLDAILFTQEDVSIVFSFTRSYFHVEVERPRELVAFLSTLLPLKRVSELYIALGFNKHGKTELYREIARHIAETGEAFVPARGDKGLVMSVFTLPGLDVVFKVIKDEFKPPKQTTRREVMDKYRHVFRHDRAGRLVDAQEFEHLAFPADRFSPEVLRELSEECRGSIEIGRAEISVKHLYAERRVTPLNLFIREADEWTARQAVLDFGRALKDLAATNTFPGDLLLKNFGVTRHGRVIFYDYDELTRVTDCVFRDLPTPSGDDEETSGEPWFYVGQDDVFPEELLPFLGLAGRLREVFLQAHGDLLTARYWRAIQERIREGEIVDIYPYREEQRLVHGYE
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.