PharMolix/UniProtQA huggingface dataset:
Protein: ZFP62_MOUSE
Sequence: MSYLKTTMEDEESSKKNENDSNADSQCPSVGFFHKDHMQKSKTGDTCDLFPKWKILKEGKSSIREMIDTHTNAANIKLEQDDETSEKSFYPSTNTMHQTIPTEPNCTKQGEHTENINGNVHPAHIADKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRIHTGEKPYECDICGKAYISHSSLINHKSTHPGKTSYTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHKRIHTGEKPYGCDECEKAYISHSSLINHKSVHRGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKAFNIRSNLTKHKRIHTGEESLNMANMESHSGTFQKMIYYEGGNSLDGTRMQMPVWEAEHAKSQRNQIEEKLYEYNNF
What is the function of this protein?
May play a role in differentiating skeletal muscle.
What are the official names of this protein?
Zinc finger protein 62, Zfp-62, ZT3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDH_RHILO
Sequence: MSNMMKALVKAKAEPGIWMEEVPVPEIGPNDVLIKIRKTAICGTDVHIYNWDQWAQKTVPVPMVTGHEFVGTVADFGAAVTEYKVGQRVSGEGHIVCGHCRNCRAGRGHLCRNTLGVGVNRPGAFGEYLAIPQHNVVPIPDDVPDEIAAIFDPLGNAVHTALSFDLVGEDVLVTGAGPIGIMGALVAQCVGARKVVITDINPVRLALAKKLGVQHVVDASKEKLRDVMPVLGMTEGFDVGLEMSGAAPAFRDMIDTMNNGGKIAILGIAPTGFEIDWNKVIFKMLHLKGIYGREMFETWYKMIALVQGPLDVSGLITHRIGIDDFQEGFDAMRSGSSGKVVMDW
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_DESPS
Sequence: MIKNITGIAMSGGVDSTATAILQKQKGPVLGFFMKLNQPDYETQRDRVSQIAQKLDIKLEIIDLTEEFQEYVLKYFSASYFKGLTPNPCIICNKEIKFGLFQQAILRQGVERIATGHYAQIHKTAAGYQLHKGVDPHKDQSYFLSRLSQEQLAHSIFPLGGMHKGAIYDLVEAHGFHDFRGTESQDVCFLEQDNVVDFLEQTAEFSASSGNIVMNDGKILGKHKGLHRYTVGQRRGLGISYPVPLYVINLDVKNNNVIVGENEQLFHKTMAISDIHWISQPEREDLLHASVHIRSTHKGAQASVILKENNRASVIFDEPQRAITPGQFATIYKDTQVLGSGVIL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ET1_ARATH
Sequence: MLVVLQIHSSINVKVFASRLRKHFFFTRRKITRIATCLSSSRCPLYPSHWNLCRWNNKQGGTEIGLLIGGLIVFRQTLKSDQETKREQKKRDWILVTAFPSPSCSPCSRETTTFELIMTPFFQSGRVSPDLCFCVNPFQKLQNSQDFCGLLLNFSRFRSKAKGANEKENFREGKDLVGRNRVQGAFQGLYELSHDHGRKDDVLVANLGQPESIRSRLRSYSRSFAHHDLLKQGLSQTILPTTQNKSDNQTEEKKSDSEEEREVSSDAAEKESNSLPSILRLSRSRPQPVSEKHDDIVDESDSASACGVLLEDGTTCTTTPVKGRKRCTEHKGKRLSRVSPGIHIPCEVPTVRECEETENICGVILPDMIRCRSKPVSRRKRCEDHKGMRVNAFFFLLNPTERDKAVNEDKSKPETSTGMNQEGSGLLCEATTKNGLPCTRSAPEGSKRCWQHKDKTLNHGSSENVQSATASQVICGFKLYNGSVCEKSPVKGRKRCEEHKGMRITS
What is the function of this protein?
Transcriptional regulator involved in the regulation of cell differentiation in meristems (By similarity).  Binds DNA without sequence preference (PubMed:22226340).
What are the official names of this protein?
Protein EFFECTOR OF TRANSCRIPTION 1, AtET1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm in non- differentiating cells and to the nucleus in differentiating cells.
Protein: YBHG_SALG2
Sequence: MKKPVVIGLAIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDTIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLSAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNYEARHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DUT_SHIDS
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CDA_PESTX
Sequence: MLAPLFAALLAGAATASPIQERQSSVPVGTIITACTVPNTFALTFDDGPFAYTSELLDLLSSNGVKATFFLNGQNWGSIYDYTSVVTRMDAEGHQIGSHTWSHADLATLDAAGITSQMTQLETALTSILGKVPTYMRPPYFSTNALALSTLGGLGYHVINANIDTLDYEHDDDTIGVAFTNFQNGLASGGTVSLMHDVHAQTVHVLVQEAINAIKAKGLTPVTVGTCLGDASANWYKSGGGSGTTPPPATGGPSPDDTCGGSNGYVCQNSQCCSQWGWCGTTSEYCAAGCQAAYGPCT
What is the function of this protein?
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine polymers in chitin to form chitosan and acetate (PubMed:27901067).  May play a role in evasion of the host immune response; plant chitinases liberate chitin molecules from the fungal cell wall which act as elicitors of the plant immune response, deacetylation of the liberated chitin neutralizes elicitor activity (PubMed:27901067).
What are the official names of this protein?
Chitin deacetylase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_SINFN
Sequence: MITFPHRHLLGIKGLTEQDITLLLDRADEAVKISRQREKKTSSLRGLTQINLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMHPDVLVVRHSSAGAAALLAQKVSCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLNQMGARVRVVAPATLLPAGIEQMGAEVYRSMAEGLKDADVVMMLRLQRERMAGSFVPSVREYFHYYGLDAETLKAAKDDALVMHPGPMNRGVEIASEVADGPQSVIEQQVEMGVAVRMAVMETLLLSQDQGPRP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RBL_NITOC
Sequence: MGKSETIAEGKDRYQAGVIPYKKMGYWEPDYQPKDTDIIAMFRITPQPGVDPEEAAAAVAGESSTATWTVVWTDRLTDCELYRAKAYRADLVPNTGEGTKNEAQYFAYIAYDLDLFEPGSIANLTASIIGNVFGFKAVKALRLEDMRIPVAYLKTFQGPATGVVVERERLDKFGRPLLGATTKPKLGLSGRNYGRVVYEALKGGLDFVKDDENINSQPFMHWRDRFLYCMEAVNKASAATGEVKGHYLNVTAATMEDMYERAEFAKSLGSVIIMIDLVVGYTAIQSMAKWARKNDMILHLHRAGNSTYSRQKNHGMNFRVICKWMRMAGVDHIHAGTVVGKLEGDPLMIKGFYDTLLDSHTPTSLEHGLFFDQDWASLNKVMPVASGGIHAGQMHQLIQYLGEDVILQFGGGTIGHPQGIQAGAVANRVALEAMILARNEGRDYVKEGPQILQDAAKWCSPLKAALDTWKDVTFNYESTDTADFVPTATASV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RL7_CHLAD
Sequence: MSKIDTIIEMIEGLNVLELVELKKKMEEKWGVTAAAPVMAMGVAAPVAAAGDGAAAAAPAEEKTEFDVILKEAGPNKIQVIKVVRELTSLGLKEAKDLVEGAPKPVREGVSKEEAEAAKAKLTEVGAVVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: APTIR_ACTS5
Sequence: MRYDAFISYSHAADGALAPAVQRGLQRLARRWHRPRALEVFRDQTGLAVSHALWSSIKVALDQSEFFVLLASPEAAASPWVNQEIEHWLSRHSVDRLLPVVTSGEWVWDADAGDVDLERSTAVPPALRGVFGEEPRHLDLRWARAEHELDLRHGRFRDAIAELAAGMHGMSKEDLDGEDVIRHRQMLRMRRGALAVVCALLLLVAGTAVAWRNARGEVTATNVALQRQRAATAAEQHRTEEAADQARSQQQIVEAEQQRAQKAAEEARGQQAVAEAEQQRALRAAGEARRQEGIAAAEQRRAQKAAAEARRQRGVADAEKAKANRAAAEAERQRKIAADEQRKAHEAAAEAERQREEAVKQQRIAIGRRLLGQAGEARDRDPRTAIQLGIAARHIYPGPQSQAGLVETLVRTHYAGTVTGHTAVVSAVALSGDGRTLVTDGLDGTVMVWDPTDRAAPRRLAQLTSSTAPVYTVALSGDGRTLVTGSEDGTAMVWDLTDRAAPRRLAQLTGHTDVVDAVALSGDGRTLATGSFDGTAMVWDVTDRAAPRRLAQLTDHTAPVTAVALSGDGRTLATGSDDHTAMVWDLTDRAAPRRLAQLTGHTAGVDAVALSGDGRTLATGSYDGTAMLWDLTDRAAPRRLAQLTGHTAQVYTVALSRDGRTLATGSEDHTAMVWDLTDRAAPRRLAQLTGHTDAVDAVALSGDGRTLATAASITRRCCGM
What is the function of this protein?
NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide.
What are the official names of this protein?
NAD(+) hydrolase ApTIR, TIR domain-containing protein in actinoplanes, ApTIR.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ILVD_SHISS
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSEQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CHRC_CUCSA
Sequence: MAFVSQFNQLPCKTLALNPPQPQLTSKPSVFPIASIGATARAAAGKSLISVRPAFKVRAVLNDDEWGEDKDEKYGDDSSVAVAEKEEEKPLEPSEIYKLKKALVDSFYGTDRGLRVSRDTRAEIVELITQLESKNPTPAPTEALTLLNGKWILAYTTFAGLFPLLSRNLPLVKVEEISQTIDSENLTVQNSVQFSGPLATTSITTNAKFEVRSPLRVHIKFEEGVIGTPQLTDSIVIPDNVDFLGQKIDFTPFNGIISSLQDTASNVAKTISSQPPIKFSISNTRVESWLLTTYLDEDLRISRGDGGSVFVLLKEGSSFLSL
What is the function of this protein?
May be involved in carotenoid sequestration within chromoplasts.
What are the official names of this protein?
Chromoplast-specific carotenoid-associated protein, chromoplastic.
What is the protein family that this protein belongs to?
Belongs to the PAP/fibrillin family.
What are the subcellular locations of this protein?
Plastid, chromoplast.
Protein: RS10_BURM7
Sequence: MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YDCQ_BACSU
Sequence: MSDFLNKRFWKYRGKRIRPYMRNNVKLAGAIIFVPVFLLSMFLFWREQLIHFDLSQVIKNFEWNVPLIIKSVLCSVLIAVGSIVASYFLLFDSYKKILHRQKIAKMIFSNKFYEKENVKVRKIFSNETDSKEKITYFPRMYYQVKNNHIYIRIAMDMSRFQNRFLDLGKDLENGLFCDLVDKQMEEGFVCFKLLYDVKKNRISIDDAVAENGVLPLMKHISWQFDKLPHMLIAGGTGGGKTYFMLTIIKACVGLGADVRILDPKNADLADLEEVLPKKVYSQKNGILMCLRKSVDGMMERMDEMKQMSNYKTGENYAYLGLKPVFIFFDEYVAFMDLLDMKERNEALSYMKQLVMLGRQAGYFLVLGAQRPDAKYLADGIRDQFSFRVSLGLMSDTGYGMMFGDVEKAYVNKKETGRGYANVGTGSVLEFYSPIVPKGYDFMSSIKNALVGVEGAQATAVASGSVSDQTASGEGVSEANG
What are the official names of this protein?
Ftsk domain-containing protein YdcQ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEC11_ARTGP
Sequence: MFAELAPYLSNPRQTLAQILNFALVLSTAFMGWKALSVYTNSSSPIVVVLSGSMEPAFQRGDLLFLWNNSPRAEVGEIVVYNVQGKDIPIVHRVIKAFGTGDGGKKSQRRLEKEADKRSGPGLSSPISHQMLTKGDNNIADDTELYAQGQDYLDRKLDIVGSVRGYIPAVGYVTIMLAENPWMKTVLLGIMGVMVMLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: SECA_STRP7
Sequence: MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKSPMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDLAPEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: MPGP_ECO27
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLHEANVPVILCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQNIDGFPRIISGISHSEICQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDEHMAQFIARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGRRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD1_SYMTH
Sequence: MSMAEDLHLEEQRPERMTLSIGPHHPATHGVLRVKLELEGETVVKAEPETGFLHTGIEKTAEHLTWNQATTVMDRMDYLSPISNNTGYVMAVEKLLGIEDRIPEKARVTRVILLELNRVASHLVGLGTGGLDYGNIGTPIFWAFELRDRILDIFEHTTGQRMNPSYMRVGGLAYDLPHNFKEMVEDFLKVAPGRIQELKDVMLHNPIFVDRAKGVSVITYEQALRYGLTGRNLRVTGSDYDVRKYYPYLGYENYDFKVPVYTDGDSWSRVAITFDEMFESLKIIRQALDNLPWDDRYIIDDRKLVLPPKQEVKHSMEALIHHFKLVHHGFDVPAGEVYVSIESPRGEIGFYVVSDGGNKPMRVRVRPPSFYAVYSLPVLLEGHLLSDMVGAIATIDPVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 1, NADH dehydrogenase I subunit D 1, NDH-1 subunit D 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCHM_BPT6
Sequence: MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDPTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHIVKKDYKGEWK
What are the official names of this protein?
Deoxycytidylate 5-hydroxymethyltransferase, Deoxycytidylate hydroxymethylase, dCMP hydroxymethylase, dCMP HMase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: RL4_STAES
Sequence: MANYDVLKVDGSKSGSVELNDAVFAIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGTIRAPQWRGGGVVFGPTPRSYAYKMPKKMRRLALRSALSFKVQENSFTIVDTFGFEAPKTKEFKNVLTTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDLTSADSVIITEAAAKKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: THIE_KINRD
Sequence: MSPRPAFDPTLYLVTDTGLCGPRGVPAVVRAAVAGGVSAVQVRAKDGGDRERLALVRAVQDVLRGTGVALIVDDAVDIALIAGADGVHLGQSDLPAAEVRRLAPDLLLGLSVSTPAQAAAVDPAVVDYLGVGPVRATATKPDAAAPLGPEGLRAVVAAAPVPCVAIGGIHPDNLDALRGSGIAGFCVVSEVCAAADPEAAARALRTQWHGRAS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: URK_ECOL6
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YME2_DEBHA
Sequence: MSGYQRPFIRNYASDVEDLKKEADRLETDKSASTTGVLDYEKQSEVVLYFDHIYPMPISGLSLKRKFLSPIQNRVTTDDLKQKVLDLSSTDSNPLPENTKISEFVPLKRDAGAFVKFEVPPETTCKELINQIVSNLEENEVQHNKNIFNYVKNLFWNKFPKCYQVKGTPWIEDLRRYPSPKLKVIFEGDPLTEEELYLLFRRYGLIVDIIPVSSSNPTATIIFKYLRSAVCAKNCITGISLNSSMTTLHLQYIPIERVNYLMDFIVNHQKITIPAIVALLATLAVLIFDPIRQLFIEQHITHKYSLETYKDNRYVKVVYYPYRSLVQWLNNSYDYIDEKLNQVYEGKGDLEVTSEDSENINILWNERFEKIKQLKLWIYENINTFIVVKGPKGSGKEEFVLDHTLNNDEKLKRKVLYIDCDALVKARSDNGLIKTTARQLGYFPVFTWTNSISQFVDLGVQGLTGQKSGLSESKETQLKNMFSLTTQALRNIALSDYEDYRNDTIKQQKRRTRKTENNTDEKPSISVEEEIIKEEDYLQQHPEAKPIIVVNNFQRKSDGNNDMIYKLIAEWTSSLVQSNMSHVIFITHDVGSVQHLTDSLPNQVFKTISLSDASQRSAKQYVWNQLNDPSLMNPDSLDKYIEPLGGRMLDLQAFIRRIKSGESANDALSEMVNQASEQITTFFLNNTVANESDSNWNTAQVWAIMKFLSENDSFEYNELSKISLFKSSNETLATLAALEKHDLISFTREKGVLSRISTGRPLYKAAFKELINDRKVYKLYETDYYNNLITIESTKIFKLEDEINKISRLSDIKYLKNRLEYVSSKINTATETIMKYEEKIKEIGKLNEKSSSSFLGIKFN
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ACPH_ESCF3
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEENFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRRETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFTCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: AROQ_BLOPB
Sequence: MVNTFRILLINGPNLNLLGIREPHIYGYEALSDVVANLYKTSESLGIHMDHFQSNAEHELIECIHKSYKNSDFIIINPAAFTHTSIALRDAFLSVNIAFIEVHLSNIHIREKFRYHSYLSDIALGVICGFGVYGYHCALHMAHKYLSKKINK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CAH2_TRIHK
Sequence: MSHGWGYADHNGPQKWCENFPIANGPRQSPIDIQTKGASYDDTLKPLKLKYDPTTSLDILNNGHSFQVTFADDNDSSMLTEGPISGKYRLKQFHFHWGASDGKGSEHTVDGKCYPAELHLVHWNTKYASFGEAANKPDGLAVVGVFLQIGEDNPKLQKILDAMDAIKSKGKQTSFTNFDPTCLLPKSLEYWTYPGSLTTPPLYESVTWIVCKQPISVSSEQMKKFRSLLFTAEEEKACCMVNNYRPPQPLKDRKVCASFK
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 2, Carbonate dehydratase II, Carbonic anhydrase II, CA-II.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_STRPD
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTQATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED19_MOUSE
Sequence: MENFTALFGAQTDPPPPPSALGFGPGKPPPPPPPPPGGGPGAAPPSTATSAPAGADKSTAGSGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKEKLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILGGSFNPITGTMLSGFRLHTGPLPEQCRLMHIQPPKKKNKHKHKQSRTQDPVPPETPSDSDHKKKKKKKEEDPERKRKKKEKKKKKNRHSPDHPGMGSSQASSSSSLR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.