PharMolix/UniProtQA huggingface dataset:
Protein: TCPQ_DICDI
Sequence: MLGLTDMLKDGAKHFAGKDEAILRNIDATKQLSEITRTSLGPNGMNKMIINHLEKLFVTNDAATIIRELDVIHPAAKMLVMAAQMQEQEMGDGTNYVVTLTGEFLQKAATLLEMGLHPSEIITGFEKAGAKLQEIIESMIVYNLKDITDKKEVTKCLKSAIASKQYGYEEFLSEIITNACLQVLPKKAVNFNIDNVRVTKIPGGGVTDTSVIKGFVIPMDAEGTIKRMEKAKIAVFTMGIDLGRTETTGKVLITNEDELLQFSKGEEDSIRETITAIANTGVKVIISGSTVSELALHYIERFKIMLVRIQSKFQLRRVCKAIGATPLVKLGAPIPEELGYCDEVLVEEIGSTKCCIFRQNKEESEISTIVVRGSTNNILDDIERAIDDGVNVFKGMCKDGRFLAGAGAFEIEASRKLQAFADATPGLSQYSIRQYAEAFEIIPRTLAETSGHDSSKAISNIYAAHTKGNTNYGLDIESGQPKSVLEMDVLDAFASKLFAIKLATNTANTVLRVDQIIMSKPAGGPKPPKMGPTDADD
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODHI_CORGL
Sequence: MSDNNGTPEPQVETTSVFRADLLKEMESSTGTAPASTGAENLPAGSALLVVKRGPNAGARFLLDQPTTTAGRHPESDIFLDDVTVSRRHAEFRINEGEFEVVDVGSLNGTYVNREPRNAQVMQTGDEIQIGKFRLVFLAGPAE
What is the function of this protein?
An essential component of the PknG signaling pathway.  When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase.  When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase.
What are the official names of this protein?
Oxoglutarate dehydrogenase inhibitor.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_COXB1
Sequence: MALNLEQKKAMVAEITDIANQAVSAVAADYRGLTVSEMSDLRKSAREARVHMRVYRNTLARRAFKETTYACLEEVLTGPIVLFFSQEEPGAAARLIEKFIKEHERLEVKGLALGGELLPAEKLKAVARLPSREEALSQLAAVLLAPVTKLVRTLNEPIAQVARVMAAVRDQKAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PYRF_MAGSA
Sequence: MINPVYVAIDTTEAARAIALAERLKGQVGGFKLGLEYFTANGPAGMEAVSGLGMPLFVDLKLHDIPNTVAAAMKGVVRLGAAITTIHASGGAAMIRAAVDAANDEAAKLGIAPPAVVAVTVLTSLDQAGAEQVGFERPVLDQVKRLATLAQDSGAAGIVCSPLEVEAVRALCGPDFKLVIPGIRPAWSEAGDQKRFLTPAEARAKGADVLVIGRPITAAADPAEAAGRIKAELGL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RSSA_BOVIN
Sequence: MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTAAQPEVADWSEGVQVPSVPIQQFPTEDWSAQPSTEDWSAAPTAQATEWVGTTTEWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.  Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.  Acts as a PPP1R16B-dependent substrate of PPP1CA.
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40, Protein C10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C- terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus. Colocalizes with PPP1R16B in the cell membrane (By similarity).
Protein: RS14_YERPA
Sequence: MAKQSMKAREVVRVKLANKYRAKREELKAIISGVNSSDEDRWDAVLKLQSLPRDSSPSRQRNRCNQTGRPHGFLRKFGLSRIKVRETAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS8_MYCSK
Sequence: MTMTDPIADFLTRLRNANSAYHDEVTLPHSKIKANIAEILKSEGYISDYRTEDARVGKSLVVQLKYGPSRERSIAGLRRVSKPGLRVYAKSTNLPRVLGGLGVAIISTSSGLLTDRQAARSGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GLND_YERPN
Sequence: MSDNHTEHSLSLTLTPTISEQPALPSTYLDSDIHCPILKQRLDAFQRWQAEAFNSGTSAEVLIAARSDYIDHLLQRLWTFYGFDKVPETALVAVGGYGRGELHPLSDIDVLVLSKQRLNDEQAQRVGQLITLLWDLKLEVGHSVRTLEECLLEGLADLTIATNMIESRLICGDVALFLQMQKHIFSDSFWPSPQFFHAKVVEQQERHKRYHGTSYNLEPDIKSSPGGLRDIHTLLWVARRHFGATSLSEMVDFGFLTNAERNELNESQSFLWRIRFALHLVLTRYDNRLLFDRQLSVAQLLRYEGEGNEPVEHMMKDFYRMTRRVSELNNMLLQLFDEAILALDANEKPRPLDEEFQLRGDLIDLRDENLFVRQPEAIMRMFYLMVRNQDIKGIYSTTVRRLRHARRHLKAPLCHIPEARKLFMAILRHPGAVSRALLPMHRHSVLWAYMPQWGSIVGQMQFDLFHAYTVDEHTIRVLLKIESFADEDTRPRHPLCVELYPRLPQPELLLLAALFHDIAKGRGGDHSILGAHDAVEFAEQHGLNSRESQLVAWLVRCHLLMSVTAQRRDIQDPAVIQQFSAEVQSETRLRYLVSLTVADICATNENLWNSWKQSLLRELYFATEKQLRRGMQNSPDLRERVRHHRLQALALLRMDNIDEEALHRIWSRCRADYFLRHSPNQLAWHARHLLEHDSTKPLVLVSRQATRGGTEIFIWSPDRPSLFAAVVGELDRRNLSVHDAQIFTNRDGMAMDTFIVLEPDGSPLAQDRHPIISHALQQAINRSDYQHPPRVRRLSPKLRHFSVPTEANFLPTHNERRTYLELIALDQPGLLARVGKIFADLGLSLHSARITTIGERVEDLFVLADKDRRALSLETRRELAQRLADTLNPNDKL
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MAF1_MOUSE
Sequence: MKLLENSSFEAINSQLTVETGDAHIIGRIESYSCKMAGDDKHMFKQFCQEGQPHVLEALSPPQTSGLSPSRLSKSQGGEDESPLSDKCSRKTLFYLIATLNESFRPDYDFSTARSHEFSREPSLRWVVNAVNCSLFSAVREDFKALKPQLWNAVDEEICLAECDIYSYNPDLDSDPFGEDGSLWSFNYFFYNKRLKRIVFFSCRSISGSTYTPSEAGNALDLELGAEEADEESGGGGGEGRAEETSTMEEDRVPVICM
What is the function of this protein?
Plays a role in the repression of RNA polymerase III-mediated transcription in response to changing nutritional, environmental and cellular stress conditions to balance the production of highly abundant tRNAs, 5S rRNA, and other small non-coding RNAs with cell growth and maintenance (By similarity).  Also plays a key role in cell fate determination by promoting mesorderm induction and adipocyte differentiation (PubMed:30110641).  Mechanistically, associates with the RNA polymerase III clamp and thereby impairs its recruitment to the complex made of the promoter DNA, TBP and the initiation factor TFIIIB.  When nutrients are available and mTOR kinase is active, MAF1 is hyperphosphorylated and RNA polymerase III is engaged in transcription.  Stress-induced MAF1 dephosphorylation results in nuclear localization, increased targeting of gene-bound RNA polymerase III and a decrease in the transcriptional readout.  Additionally, may also regulate RNA polymerase I and RNA polymerase II-dependent transcription through its ability to regulate expression of the central initiation factor TBP (By similarity).
What are the official names of this protein?
Repressor of RNA polymerase III transcription MAF1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL19_CHLMU
Sequence: MGNLIKELQDEQCRTDLVDFCVGDTIRVATNISEGGKERVQVFQGTVMARKGGGAGETVSLHRVAYGEGMEKSFLLNSPKVVSIEVVKRGKVSRARLFYLRGKTGKAAKVKELIGPRAAKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MC3R_HUMAN
Sequence: MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  This receptor is mediated by G proteins which activate adenylate cyclase.  Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
What are the official names of this protein?
Melanocortin receptor 3, MC3-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_STRM5
Sequence: MRIVFAGTPEFAVSSLRAAARHHEVVAVYTQPDRPAGRGRGLAPSPVKLEAVARGIPVYQPESLKDEAAQQQLRDLQPDLMVVVAYGLILPKAVLAIPTHGCWNVHASLLPRWRGAAPIQRAIQAGDTKTGVCLMQMEAGLDTGPVLLHQELPIATTDTGGQLHDKLAELGAQVLSDGLGLLRAGIKPVARPQPEQGVTYAHKLDKAEARLDWVLDAGALARTVRAFNPWPIAEASLAGERVRIHGAVALDLAHGQAPGTVLAASRDGIDIACGQGALRLRVLQREGGKAITAADYLNARRDLRVGA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DEC12_DROME
Sequence: MRLFSLLPLLALLVVQAAGQSEVTSDDPATDAGSTTNSTTDTKPRIPSQDEILGQMPSINPIRTGNPQMDAFYMMFPALGSLLKWGSLFPAYSILGAIPDNLQPTAAASKVVLVLADDATAKTRVARQNPPPNPLGQLMNWPALPQDFQLPSMDLGPQVGSFLAQLPAMPTVPGLLGAAAPVPAPAPAPAAAPPPAPAPAADPPAAPVPDAPQPAILGQAALQNAFTFFNPANFDASSLLGQSVPTFAPPNLDFVAQMQRQFFPGMTPAQPAAAGTDAQASDISEVRVRPEDPYSQEAQMKIKSALEMEQERQQQAQVKDQEQVPLLWFRMPTTQNQDATEEKTLEDLRVEAKLRAFERQVIAELRMLQKIELMAKQMRSSAAAQNGDSPYRISYPLSRTPIHKITRADIEQALRDDYVRRLVNKEAQRRARNSGINTQKANALKRQAKSQDQTLSKEDIVQIMAYAYRMANEQMESEKGKQDKVYAAYRTEQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQQNQQQIQQNPMMVQQRQWSEEQAKIQQNQQQIQQNPMMMQQRQWSEEQAKIQHDQQMAQQMAQQGLMMTEQRQRQWSEDQAKIQQAQQMAQQTPMMMPQMQQRQWTEDPQMVQQMQQRQWAEDQTRMQMAQQNPMMQQQRQMAENPQMMQQRQWSEEQTKIEQAQQMAQQNQMMMQQMQQRQWSEDQAQIQQQQRQMMQQTPMMMKERQWAEENPQSVQQQGPMMMQQQMPSMMQREVEDEDNKAEDDLVGEAGPQMPENEGTARHKVDALGVGGNKRKKSKSKSAPPTVINYYYAAPQRPVVQSYGTSYGGGGYGSNAYGVPRPVNSYQSQGYRAAVGNDEVDEMLRQHQTMARATHFRQ
What is the function of this protein?
Required for proper assembly of the eggshell.
What are the official names of this protein?
Defective chorion protein, FC106 isoform.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_ALBFT
Sequence: MTSSTSQITGSIVALVTPMLDDGSVDYPALRKLIDWHIAEGTDCIGVVGTTGESPTVNVQEHCEIIRVAVEQAAGRVPIMAGCGANCTAEAIELTQFAKKVGADCQLQVVPYYNKPTQEGQYRHFKAIAEAVDLPMVLYNVPGRAVADMAHDTVLRLAQVPGIVGIKEATGQIDRAQWLIREAPKGFAIYSGDDPTAVALMLCGGHGNVSVTANIAPRLMHELCVAAMAGDTKRAMEIQFKLLPLHKNLFIEANPIPVKWAVARLKLCGGTLRLPMTPLTPANEAALESALHASGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAR2_MOUSE
Sequence: MSSMQMDPELAKQLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLYYSSVDKANPREVGPRMGFFLSLKQRGLTVLRWNAVQEEVDLSPAPEAEVEAMRANLPDLDQFLGPYPYATLKKWISLTNFISEATMEKLQPESRQICAFSDVLPVLFMKHTKDRVGQNLPLCGTECRSYQEGLARLPEMRPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKQFPGNPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSESAMGKYHALYISLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVEATLRKKAEKFQAHLTKKFRWDFTSEPEDCAPVVVELPEGIETA
What is the function of this protein?
Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.
What are the official names of this protein?
Protein AAR2 homolog, AAR2 splicing factor homolog.
What is the protein family that this protein belongs to?
Belongs to the AAR2 family.
Protein: PDRP_SINFN
Sequence: MENRKNYFHLHLVSDSTGETLIAAGRAAAAQFQSSHALEHVYPLIRNKKQLMQVLDAIDGAPGIVLYTIVDRELAGMIDQRCREIGVPCVSVLDPIIELFQSYLGSPSRRRSGAQHVMDADYFARIEALNFTMDHDDGQMPADFNEADVVLIGVSRTSKTPTSIYLANRGIKTANIPIVPGVPLPDGLLRATKPLVVGLIASADRLSQVRQHRVLGTTQSFHGEEYTDRAAISEELKYARTLCARNNWPLIDVTRRSIEETAAAIVALRPRLR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RTBDN_ICTTR
Sequence: MACRSHIQPSDLACTMQLALAWIILGACGGSHQFQARSQGHLGLASNLGTNQVQLAGDLQASGPQPYMMIQDPDSQAFPLPEPCCPSEMDTPETSGPGIFPPRCRTPSSGCESFLGHLQRALRNRFHLLLLGVRQAPPLCEELCQNWFATCEADITCGRTWLWPSGKRSCEGRCRTYGQTFADGVDLCRSVLGHILPVAAPGSRHCLNISISLLPRPRPGRWARETISQRSRRRGTGILDAGGSGSGSGSGSGP
What is the function of this protein?
Riboflavin-binding protein which might have a role in retinal flavin transport.
What are the official names of this protein?
Retbindin.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Cell membrane; Peripheral membrane protein.
Protein: YR748_MIMIV
Sequence: MHNLENKNASNKKPKKIVVSDLIAILTYLMEIKNKMTNKELWKIRHICLTGSYNNNQMSIMKILMNKFPKTINVPFDKQNNTYLHQSIFNRHKIFVDFFMNELNDNINYRSKNKIGISHLHALVNYGYIDHIETAIIKDPGAIQQLSDDGQNILEFAVIPCFSIISNKNSEPYKKSNTTIINIIKTLSKSITKLDLQSRNKMGYRAIECAVRYCSTDVIDELISLGFSINESRLKNRIFPTINNNDLIGFATQIDRLDMVKHLINIGAPIHMYHINKHNKLLVPTCLVVAIKFKRDQCIHYLLNLPESIQALSNNTIKKYLFNIATNAGCTNHEIISKLCPKTYDDKKLRKNCNRYKISVFEQHENKIERNIKNYYKRRFMILDSISNMLSILCSIYNFSDNDSDLHKITRTVVSLEANLLLKYTTINNVYETVADFVDHIELTDIQYCFETVSNSEIMKASDCIINEYFISMKKLGIFKKINRLIKSKNIINTLLNEFDSDSESTDDDSDTKRACSCGCQSCYDSDEDPVCDSNESDNSNDINNHVKSDNKLNSSNDYYDEDDSEDNYNNQSDDEPLVKNDVVNTINTITPNQNLENTFNENNVMINNINFEKTLNNKHQSFQDNICENISENISEKIPNNNRDNNCNNNHNNNIQGDKELFDKPLHLQYTRLTKLHEHYIHKSLYKLRHPIKLNQYDTVYNLLTSLDPYVKNNNNILVFNSDNKLIAKIFSLSIKSDTDYINDINSENDNVNMYHEKTKLQIRSKPSRWIRFYSQNICGLDKQDPNHMFPFVLDRILNDWPCIERRIRDKIHPDGLDSLLYFYGELLINGEMIRGCFEYFINSNNSVFHRLFREEYKLPQNIRDTLDESINVLSY
What are the official names of this protein?
Putative ankyrin repeat protein R748.
Protein: ATPL_ECOLU
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GIP2_CAEEL
Sequence: MMRTAHKDREPWRDIRRSLLSKWQGVRVCDEPSPWYMSIPTPFSQFHNVLPEEQEEMVFTELKLFLVGNQTENIRIDEYDKHDLPISILANISFDPFIRSELERFHDILVTVATIKICCYAITHDSVTFSSISSAVASTIEKKVNGFITKICTKLSGSTEANQQMNQLLREMHTIHESLNFYNGIVKSIYLDQLIGGQVLSLLDSKRRHVFSGNVVQNLDDVFQAGWKVFARSIGRLVCKFEADHMDYEFVIWSTKQMTDSQCKTLVPSNPSRQIKSSRYVVIESLCPDFFKKYLDILVRCAEFGDSAKSDSSLRRSTSKKINESESVESVMEDVRNVDWSNLDVATTVRMLVQFSRKESACLLREITSATNVDQAIRDIHDLLIKGSCAHDVMLFGLKADILQKPIDEVGNIRMKKLTNDVLGAAAEKHHPFWKYFSFVIDKQNVFEMLGQRTSLGGNADNLRDNVTPMLFECISVKMDCPIEIEPIISMKAVFILTPVFRIWIQLHVASYTIANYRDSIRGQMPSRSLGDIAMKKHLMHALDAEISSIKQKWVGYVDLLINLYYERIQKAASLDEYTECQDILASDVTNMMGISELSQLENIKDILNIIWNYDNADSNLADLIADFEEVQSRARMDVVVA
What is the function of this protein?
Recruited to hemidesomosomes in early embryonic elongation to direct the nucleation and growth of non-centrosomal microtubules.
What are the official names of this protein?
Gamma-tubulin interacting protein 2.
What are the subcellular locations of this protein?
Cell junction, hemidesmosome. Cell junction, adherens junction.
Protein: PAND_METPP
Sequence: MNRLMLRAKLHRATVTEADLHYEGSCGIDAALLEAADMREFEQIELYNVNNGERFSTYVIPAPPGSGVISLNGAAARKAHVGDLLIICTYAPMNDAEVATHKPKVVLLGPGNRIESVRKF
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEAP2_CAVPO
Sequence: SVVLLICLLLLGQVDGSPVPEKSSVKKRLRRMTPFWRGVSLRPIGASCRDDSECITRLCKKRRCSLSVAQE
What is the function of this protein?
Has an antimicrobial activity.
What are the official names of this protein?
Liver-expressed antimicrobial peptide 2, LEAP-2.
What is the protein family that this protein belongs to?
Belongs to the LEAP2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARE_SACSO
Sequence: MPLDPEVRNFLQVYYKANIIDFTKYQFQEIRQKVNELLAKAVPKDPVGETRDMKIKLEDYELPIRIYSPIKRTNNGLVMHFHGGAWILGSIETEDAISRILSNSCECTVISVDYRLAPEYKFPTAVYDCFNAIVWARDNAGELGIDKDKIATFGISAGGNLVAATSLLARDNKLKLTAQVPVVPFVYLDLASKSMNRYRKGYFLDINLPVDYGVKMYIRDEKDLYNPLFSPLIAEDLSNLPQAIVVTAEYDPLRDQGEAYAYRLMESGVPTLSFRVNGNVHAFLGSPRTSRQVTVMIGALLKDIFK
What is the function of this protein?
Has a broad substrate specificity.  Hydrolyzes various p-nitrophenyl phosphates, aromatic esters and p-nitrophenyl fatty acids in vitro.  Most active against paraoxon, phenyl acetate and p-nitrophenyl caproate (C6), respectively.  Has also tributyrinase activity, but shows no hydrolytic activity toward other triacylglycerols including tricaprylin, trimyristin, tripalmitin or triolein in vitro.
What are the official names of this protein?
Arylesterase, A-esterase, Paraoxonase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: ATPB_PSEAE
Sequence: MSSGRIVQIIGAVIDVEFPRDAVPSIYEALKVQGVETTLEVQQQLGDGVVRSIAMGSTEGLKRGLNVDSTGAAISVPVGKATLGRIMDVLGNPIDEAGPIGEEERWGIHREAPSYADQAGGNELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLVIGQDHYDTARGVQYVLQRYKELKDIIAILGMDELSEADKLLVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIAGFKGILNGDYDHLPEQAFYMVGGIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMB_YERPY
Sequence: MKNTYNLRSIAAKAISQVLDQGQSLSAVLPELQKNISDKDRALLQELCFGTLRVLPQLEWCIQQLMARPMTGKQRVFHYLIMVGLYQLIYTRIPPHAALAETVEGATVLKRPQLKGLINGVLRQFQRQQVELLERAVNNDSHYLHPSWLLARIKQAYPAQWQQILDANNQRPPMWLRVNRLHHSRSEYLELLTQADINAEPHPIYRDAVRLITPCAVNHLPGFELGWVTVQDASAQGCVDLLDPQNGEQILDLCAAPGGKTTHILEAAPKAHVLAVDIDEQRLSRVKENLQRLQLQAVVRVGDGRAPDTWCGDQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDISELAQLQSEIIEAIWPKLKHGGVLVYATCSILPEENQQQIAAFLQRHPEAQLTETGTTAAPGKQNLPHPEDGDGFFYAKIIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_BUCAI
Sequence: MKIGIIGAINQETERLKKIIHFYIEKKINTYKIYIGKFKSHDVFLIKSGIGKVSASVATMILIDLYKPDTIINSGSAGSLQSFLKIGDIIIPKKTCYYDVDLTNFGYTRGQIPGYPKEFTVNEKICNFFKKNADKYQLKYIKGLILSGDTFVRENESIKILKKQFPSAIAVEMESSAIAQVCYKFNIPLIIIKSISDESDNNATVNFKENIDFVSYQLSKFVKIILENLIDM
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.