PharMolix/UniProtQA huggingface dataset:
Protein: YIP12_SCHPO
Sequence: MPSKRKRNPLQYQTSGSLDEETNQRSAFPQIDNNSASESLEYDIPLDGLDYLATVREEARKLVPFVAARREPETRETIPLRKLEIEAGKKSFDPFLRYLLNIIDKEGERLEQYMESSSLDASILPKNLQQWRVYIEHKAPCWAILAVVDLATVLEILESLSSWLEKDAIDLQSQWIFCFCYKLPELLNGEDISTLRSVLKSLRSTHTSFPALQMSASALQAVLVYRYGQKDLFQT
What are the official names of this protein?
Survival of motor neuron protein-interacting protein yip12, SMN-interacting protein yip12, Yab8-interacting protein 1-b.
What is the protein family that this protein belongs to?
Belongs to the gemin-2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAT4_ORYSJ
Sequence: MAACVDKWPPAAYLCRLPEKFYCVLPDCTATDRPVVTASAAPAPAASGSSGDYVWDVLRAEAQDDADDEPLLRKFYHDLVLSRPSLESALASLLAAKLCIPGALPQDQLRDLLAGALAAHPEAGRAARADLVAARDRDPACAKMVHCFLYYKGFLALQAHRAAHALWSDNRRAPALLLQSRASEVFGVDIHPGARIGCGILLDHATGVVIGETAVVGYDVSILHGVTLGGTGKESGDRHPKVGDGVLIGAGASVLGNVHIGDGAKIGAGAVVLRDVADGTTAVGNPAKPIIGKKAAPQRRPEELPGVTMEQRWSD
What are the official names of this protein?
Probable serine acetyltransferase 4, OsSERAT2;2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: CH10_PEDPA
Sequence: MLKPLGDRVILEAKDEEEQTVGGIVLASNAKEKSQTGKIIAVGNGTVLDNGQTVPMNVKVGDTVVYDKYAGTEVSYEDKKYLVVHEKDLVAVVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL8_VITVI
Sequence: MESQCRPNVDGVHNGVESHVKVVEKPRSVGSSSEFVLRILGLLLTLIAAVVAGVDKQTKIIPLTLIKTLPSLHVPVTAKWSDMSAFVYLVVSNAIACSYAAISLVLVTMLGRRGKGGRVLAVIVLDLHMVGLLFSANGAATAVGVLGQYGNSHVEWKKVCNVFDSFCHHLVASLALSFLGSLSFLGLVLLAILNLHKKSSTK
What are the official names of this protein?
CASP-like protein 1E1, VvCASPL1E1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDN2C_MOUSE
Sequence: MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPNLKDGTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMKHTACNVGHRNHKGDTAFDLARFYGRNEVISLMEANGVGGATSLQ
What is the function of this protein?
Interacts strongly with CDK6, weakly with CDK4.  Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
What are the official names of this protein?
Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6.
What is the protein family that this protein belongs to?
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Protein: HLGB_STAAN
Sequence: MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
What is the function of this protein?
Toxin that seems to act by forming pores in the membrane of the cell.  Has a hemolytic and a leucotoxic activity.  Promotes host AMFR-mediated inflammation by mediating 'Lys-27'-linked ubiquitination of TAB3, TAK1-TAB3 complex formation and phosphorylation of TAK1/MAP3K7.  In turn, activates host NF-kappa-B signaling pathway.
What are the official names of this protein?
Gamma-hemolysin component B, H-gamma-1, H-gamma-I.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: BIOD_BURCM
Sequence: MTAPLSLFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVVLPPELRTPFLLKAPAAPHIVAAQEGVTLDIDTIVACHREALTRADVVVVEGVGGFRVPLTDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSYADENVATIRDWLAREHGAPLLGRIPHMSPAAAESAAAMLDIAALVETLRAAQH
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_METKA
Sequence: MHAFLGNAQLPSTPRGDRLEFSEWYAEVLRSAEIMDVRYPVKGMYVWLPYGFEIRQRVVEKLRRKLRETGHEEVLFPTLIPETQLKKESEHIAGFEDEVYWVTHGGLKELDEKLALRPTSETAIYPMFALWIRSHADLPLKIFQIVNTFRYETKHTRPLIRMREITTFKEAHTAHATEEEAEEQVKEAVEIYSSFFDELGIPYIASVRPEWDKFPGAEYTVAFDTLMPDGRTLQIGTVHMLGQNFARTFEVTYETEEGDQEYVYMTCYGISDRVVASMIAIHGDERGLVLPPDVAPYQVVMVPILKKGVRRKILERAAEVEEMLREEGVRVKVDDRDMSPGRKFHYWELKGVPLRIELGARELEEGTAVVFRRDELERETYAFEELPDVVPELLEDIAMELRKRAREKFEKGIFRTDSPEEARRLVGEGIVETGWCGSERCGVRMEEEFGGDVLGTPYPEEDTEFERCPICGETAEYTVRIAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTM_STAAW
Sequence: MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene).
What are the official names of this protein?
4,4'-diapophytoene synthase, DAP synthase, C30 carotenoid synthase, Dehydrosqualene synthase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. CrtM subfamily.
Protein: Y705_DEIRA
Sequence: MKPLLCSLLLLSACAGPSEPQASGAGPAQTPPPVTVPMTPPSKKPALSAVQHWGVQLTGYGQTRLNAVHTSPFELVVVDPFDDDGTPWPAAEVRAAAQGRWLIAYLSMGAAESYRSYWQKGWKVGAPAWLLNEDPDWPGNFDVAYWDPAWQAIALAQLDRVIAQGFDGVYMDLIDAYQRHDNRPGARAEMVAWVCKIAAHARAQNPQFVIIPQNAAELIRDPGYAACVDASGNEETYVYAANRPTEAARQRELLASYRLWQQAGKPVFTIEYANQPALMKSAAERARAAGLIPYVGERSLDKLILNQP
What are the official names of this protein?
Uncharacterized protein DR_0705.
Protein: Y1228_TRIV2
Sequence: MAGHSKWANIKRQKAVVDAKKGKTFTQLSRAIILAARSGIPDPSGNFQLRTAIDKAKAAGIPNDNIERAIAKGAGTFGGDNASLEEIRYEGYGPGGVAILIEALTDNRNRTAADLRVAFSKNGGNLGETGCVSWMFDQKGVCVVSGVVDEDQLLEASLEGGAESYEMTEDETAEVFTEVANLEILNQTLKDQGFKVTDAELRWIPSNNVEVTEPDQARSLLKLIDTLEGLDDVQNVTSNFEMSENLMAVSFA
What are the official names of this protein?
Probable transcriptional regulatory protein Ava_1228.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTLC_BORPE
Sequence: MNRRGGQTAFAAIARNERAIAAFIPYSSHLTDTTLITHGADLVRTWRVQGIAFESAEPELVSQRHEQLNGLWRAISCEQVALWIHCIRRKTQAGLDARYENPFCRALDASYNARLNARQAMTNEFYLTLVYRPGHAALGKRAHHGQAEVRRQLLAHVRRMDEIGSLIETTLRSHGENHEQAITVLGCETDSAGRRYSRTLTLLEFLLTGHWQPVRVPAGPVDAYLGSSRILAGAEMMELRAPTCRRYAQFIDFKEYGTHTEPGMLNALLYEDYEYVITHSFSAVGKRQALAYLQRQRAQLANVQDAAYSQIDDLAHAEDALVNGDFVIGEYHFSMMILGADPRQLRRDVSSAMTRIQERGFLATPVTLALDAAFYAQLPANWAYRSRKAMLTSRNFAGLCSFHNFYGGKRDGNPWGPALSLLSTPSGQPFYFNFHHSGLDEDCRGQMMLGNTRIIGQSGSGKTVLLNFLLCQLQKFRSADADGLTTIFFDKDRGAEICIRALDGQYLRIRDGEPTGFNPLQLPCTDRNVMFLDSLLAMLARAHDSPLTSAQHATLATAVRTVLRMPASLRRMSTLLQNITQATSEQRELVRRLGRWCRDDGAGGTGMLWWVFDNPNDCLDFSRPGNYGIDGTAFLDNAETRTPISMYLLHRMNEAMDGRRFVYLMDEAWKWIDDPAFAEFAGDQQLTIRKKNGLGVFSTQMPSSLLGARVAASLVQQCATEIYLPNPRADRAEYLDGFKCTETEYQLIRSMAEDSHLFLVKQGRQAVVAQLDLSGMDDELAILSGNARNLRCFEQALALTRERDPNDWIAVFHRLRREASAGLR
What is the function of this protein?
Component of the type IV secretion system ptl essential for secretion of assembled pertussis toxin (PTX) through the outer membrane.
What are the official names of this protein?
Type IV secretion system protein PtlC, Pertussis toxin liberation protein C.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CYB_CHAGD
Sequence: MTIIRKSHPLMKMVNHAFIDLPAPSNISSWWNFGSLLGLCLIIQIASGLFLAMHYTSDTTSAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYLYKETWNIGIVLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSNSDKIPFHPYYTFKDLLGVIILLSLFLTFVLFFPDLLGDPDNYSQANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQLLFWTLISDLMILTWIGGQPVEPPFIIIGQIASILYFSIILLLLPIAGLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRAZ_YERP3
Sequence: MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCLLLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: POED1_ORYSI
Sequence: METEGWPALQPLLCLAWIATTLPIIVAALPIPAAAGGHLLRRLLSAFSSRGKTVRPSPASSSGSSSSKAKFTVPQKYFMHFYVVGVLATTILLLAIWFYAYMKMTPLLPESSSYSTIASHLVGSNSFSFGRVHSRTMGHKYHVWRTVFVLLLMEIQVLRRLYETEHVFHYSPSARMHIVGYLTGLFYYVAAPLSLASSCIPEAAEYLQGQVAEFIVKGRARMPDLVIDSSSLLQPLLKLGWTQWIGAVIFIWGSLHQIRCHAILGTLREHKDSDEYVIPCGDWFNRVSCPHYLAELVIYFGMLVASGGEDIPVWFLFVFVITNLSFAAVETHKWYLQKFEDYPRSRYAIIPFVC
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
What are the official names of this protein?
Polyprenol reductase 1.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PGCB_HUMAN
Sequence: MAQLFLPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRGREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPCHNGGTCLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPLIRCQENGRWEAPQISCVPRRPARALHPEEDPEGRQGRLLGRWKALLIPPSSPMPGP
What is the function of this protein?
May play a role in the terminally differentiating and the adult nervous system during postnatal development.  Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
What are the official names of this protein?
Brevican core protein, Brain-enriched hyaluronan-binding protein, BEHAB, Chondroitin sulfate proteoglycan 7.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Lipid-anchor, GPI-anchor.
Protein: ACSA_BURM7
Sequence: MSAIESVLHERRQFAPPAAVEKAAAISGMAAYRALAEEAERDYEGFWARLARETLEWRKPFGKVLDETNAPFYKWFEDGELNASYNCLDRHVAAGLGERVAVIFEADDGTVTRVTYADLLARVSRFANALKKRGVGRGDRVVIYIPMSVEGIVAMQACARIGATHSVVFGGFSSKSLHERIVDVGATALVTADEQMRGGKTLPLKSIADEALAMGGCDAVKTVVVYRRTGGNVDWHAGRDVWMHEMVANESDACEPEWVGAEHPLFILYTSGSTGKPKGVQHSTAGYLLWVAQTMKWTFDWKPDDVFWCTADIGWVTGHSYITYGPLAVGATQVVFEGVPTYPNAGRFWKMIGDHKVTVFYTAPTAIRSLIKAAEADDRVHPRSYDLSSLRIIGTVGEPINPEAWIWYHKNVGQARCPIVDTWWQTETGGHMITPLPGATPTVPGSCTLPLPGIMAAVVDETGQDVPNGQGGILVVKRPWPAMARTIWGDPERFKKSYFPEELGGRLYLAGDGTVRDKETGYFTIMGRIDDVLNVSGHRLGTMEIESALVSHELVAEAAVVGRPDDTTGEAVVAFVVLKRSRPEGEEAAALAKTLRDWVGKEIGPIAKPKDIRFGDNLPKTRSGKIMRRLLRSLAKGEAITQDTSTLENPAILEQLAEVR
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: NDHJ_MAIZE
Sequence: MQQGWLSNWLVKHDVVHRSLGFDHRGVETLQIKAGDWDSIAVILYVYGYNYLRSQCAYDVAPGGSLASVYHLTRIQYGIDNPEEVCIKVFAQKDNPRIPSVFWVWRSADFQERESYDMVGISYDNHPRLKRILMPESWIGWPLRKDYITPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: COXX_BORBR
Sequence: MSSLAAPQTGLLRQYLVLTKPRVTQLAVFCAVIGMFLAAPGMPDLSHVVFGTLGIWLLAAAAFAINCLIEQEVDARMLRTARRATARGTISDIQVLSLSGLLGGAGMLVLYHLVNPLTMWLTFATFVGYAIIYTVILKPRTPQNIVIGGLSGAMPPALGWAAVADSVPAEAWVLVLIIFIWTPPHFWALALYRNNDYIKAGLPMLPVTHGQQFTRLHILLYSFALLATTLLPYAIRMSGALYLASALALGGMFVWYAWRLYREYSDALARRLFRFSILYLALLFGALLIDHWVGLLR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H2A_PLAFA
Sequence: MSAKGKTGRKKASKGTSNSAKAGLQFPVGRIGRYLKKGKYAKRVGAGAPVYLAAVLEYLCAEILELAGNAARDNKKSRITPRHIQLAVRNDEELNKFLAGVTFASGGVLPNIHNVLLPKKSQLKAGTANQDY
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CEDA_SALCH
Sequence: MMKPLRQQNRQIISYIPRVEPAPPEHAIKMDTFRDVWILRGKYVAFVLTGESFQRSPAFSVPESAQRWANQVRQENEIAD
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.
Protein: TRUA_ECOSE
Sequence: MSDQQQLPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: FKB19_ARATH
Sequence: MASISSFGCFPQSTALAGTSSTTRCRTTVAARLADQSDDFAPLRSSGGNCGCVNNSGEFDRRKLLVSSVGLLIGALSYDSKDGDFASASQFADMPALKGKDYGKTKMKYPDYTETQSGLQYKDLRVGTGPIAKKGDKVVVDWDGYTIGYYGRIFEARNKTKGGSFEGDDKEFFKFTLGSNEVIPAFEEAVSGMALGGIRRIIVPPELGYPDNDYNKSGPRPMTFSGQRALDFVLRNQGLIDKTLLFDVELLKIVPN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP19, chloroplastic, PPIase FKBP19, FK506-binding protein 19, AtFKBP19, Immunophilin FKBP19, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: RF1_PROM0
Sequence: MEYSTLIARLKTASESFENLEVQLADPDIANDPKKLESIARERSKLEPLVLDFNKLLDTDKEIEDSKNLLKENRNDKEMESLINEELITLEESKSELIQKTTIALLPKDPRDERSVMLEIRAGAGGNEACIWAGDLARMYERYGQKIGWSVKPVSASESDMGGFKELVISVKGDSVYSQLKFEAGVHRVQRVPATESQGRVHTSTATVAVMPEADPVEVKIDPTDLEVGTARSGGAGGQNVNKVETAIDLLHKPTGIRVFCTQERSQLQNRERAMEILRAKLYEIQLKEANAKERSQRLSQVGTGDRSEKIRTYNFKDNRTTDHRLGSNFSLEPILAGQLDEVINACIAQEQKRMMEDFNKGVN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_PHOPR
Sequence: MTVKGLETHTPMMQQFLRIKAENPDTLLFYRMGDFYELFFDDAKRASQLLDITLTKRGSSNGQPIPMAGLPYHAVEGYLAKLVQQGVSVAICEQIGDPATSKGPVDRQVVRIVTPGTVSDEALLSERRDNLVAAIYQNSKGFGYATLDITSGRFMLSEPETEEAMQAELQRTSPAELLYPEDFTQMHIIEAIKGTRRRPVWEFDLDTARQQLTMQFGTRDLIGFGVEKTERGLSAAGCLLQYVKDTQRTALPHIRAITLDSKDHSVILDAATRRNLELTQNLSGGFDNTLASVLDHTATPMGSRLLKRWLHQPIRDTKQLNHRLDAIAAFKDTGMFIEVAEVLHHMGDLERILARLALRSARPRDLARMRSALQSLPQLADLLADIEQPRIGELAKYSAPMDELCELLERAIIENPPVIIRDGGVLAPGYNAELDEWRDLADGAKKFLDDLETREREQHGIDSLKVGFNQVHGFFIQISRGQSHLAPDHYVRRQTLKNAERYIIPELKEHEDKVLSSKSKALGLEKKLWEELFDQLLPHLERLQNAASALSELDVLANLAERADTLNYCRPELTDQTGIEIAAGRHPVVEQVLSEPFIANPTSLHHDRRMLIITGPNMGGKSTYMRQTALIALMAHVGSFVPAEAVKIGSLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATSKSLVLMDEIGRGTSTYDGLSLAWASAEWLAEKISAMTLFATHYFELTELPSMMDGLANVHLDAVEHGDEIAFMHAVQEGAASKSYGLAVASLAGVPKAVIKRAKAKLTQLETTGHQQAIKNPSKAPREEQQLTLLPEPSDVEEALAKVNPDEMTPRQALDELYRLKALM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: AK1D1_RAT
Sequence: MNLSTANHHIPLNDGNSIPIIGLGTYSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFKPGEEFYPKDENGRVIYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKYKPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPLGTCRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKEEMKDIEALNKNVRFVEMLMWSDHPEYPFHDEY
What is the function of this protein?
Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction.  This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism.  Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one).
What are the official names of this protein?
Aldo-keto reductase family 1 member D1, 3-oxo-5-beta-steroid 4-dehydrogenase, Delta(4)-3-ketosteroid 5-beta-reductase, Delta(4)-3-oxosteroid 5-beta-reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_SINMW
Sequence: MTNVVVVGSQWGDEGKGKIVDWLSERADIVVRFQGGHNAGHTLVIDGVSYKLSLLPSGVVRSGKLAVIGNGVVIDPHALIAEIDRLAAQGVTVTPQNLRIADNATLILSLHRELDGIREDAASNSGTKIGTTRRGIGPAYEDKVGRRAIRVMDLADLDTLPAKVDRLLTHHNALRRGLGEAEISHRAIMDELSSVAARVLPFMDTIWLLLDRERRKGARILFEGAQGTLLDIDHGTYPFVTSSNTVAGQAAAGSGMGPGSLGYILGITKAYTTRVGEGPFPTELDDEVGRFLGERGHEFGTVTGRKRRCGWFDAALVRQSVAANGITGIALTKLDVLDGLDELKICVGYTLDGQQIDHLPASQAQQALAKPVYITLEGWKESTVGARSWAELPAQAIKYVRQVEELIGAPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_HALHL
Sequence: MSKVCQVTGTRPGTGNNVSHANNKTRRRFLPNLHDHRYWVESENRWVRLRVSAKGMRIIDKRGIDAVLADMRARGERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.