PharMolix/UniProtQA huggingface dataset:
Protein: TRAF_SINFN
Sequence: MNIPLVELTSRRRRGKPLLLGLATMTMAAVGTISAAWFGGYRINLTPSEPLGLWRIVKIDRPSAVGDLVFICPPRTSAMREARMRGYLRAGLCPGGIAPLIKSVIAVAGQRVEVGVSVNVDGHPVPSSALALRDGQGRPMKPFSGGIVPTDYVFLHSPFSGSYDSRYFGPIPAAGILGLAQEVLTYAP
What is the function of this protein?
Involved in conjugal transfer of the plasmid.
What are the official names of this protein?
Probable conjugal transfer protein TraF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AMPA_CYAP4
Sequence: MDIRTTTTTATDWAGDLLALGFFEDQVELSGSLAELDQKLDGILQELIAETEFKGKAGKSAIARISSKSPIRKIMILGLGKAEDFKLDTLRRTAATIARSAKKEKGKTLGISLPLWNNDPTSTTQAIAEGIELALHQDHRFKSNSEDNNDNHAPEQIQLLGLGDQTTAIERAQRICSGVILARELVAAPANVVTPVTLAETARDLAQEYGLDVEVLGQAECEALGMGAFLGVALASDLPPQFIHLTYRPSGTPRRKLAIIGKGLTFDSGGLNLKTGGSGIETMKMDMAGSAATLGAAKVVGQLKPDVEVHFIVAATENMISGRAMHPGDILTASNGKTIEVNNTDAEGRLTLADALVFAEKLGVDALVDLATLTGACIVALGDDIAGLWSSDDALAEQILQAADHSGEKLWRMPMEEKYFEGMKSQIADMKNTGPRAGGSITAALFLKQFVKETPWAHLDVAGPVWADKENGYNNAGATGYGVRTLVNWVLGS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1347_HYPNA
Sequence: MGANRLVAVHIDEETLGASGPDAEHERRVAIFDLIEENTFGVIGEDRGPYVLALSQHERRLVFAIRTEPGEEVHTFILSLSPFRGVIRDYFTICDSYYEAIRMSTPHQIEAIDMARRGIHNEGSELLKERLEGKIDIDFHTARRLFTLICALHAGQGRAPGA
What are the official names of this protein?
UPF0262 protein HNE_1347.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: ROBO4_RAT
Sequence: MGQGEELRAAVDSGGMGLLGTKCPLPLLLLFIMGGKALDSPPQILVHPQDQLLQGSGPAKMSCRASGQPLPTIRWLLNGQPLSMATPDLHYLQSDGTLLLHRPPTHGRPQDDQNILSAILGVYTCEASNRLGTAVSRGARLSVAVLQEDFRIQPRDTVAVVGESLVLECGPPWGYPKPSVSWWKDGKPLVLQPGKRTVSGDSLMVARAEKNDTGTYMCMATNNAGQRESRAARVSIQESPDHKEHLELLAVRIQLENVTLLNPEPVKGPKPGPAVWLSWKVSGPAAPAQSYTALFRAQRDPRDQGSPWTEVLLDGLLNAKLGGLRWGQDYEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQEVTLRPGNGSVFVSWAPPPAENHNGFIRGYQVWSLGNASLPAANWTVVGEQTQLEIAARMPGSYCVQVAAVTGAGAGEPSIPVCLLLEQAMEQSARDPSKHVSWTLEQLRATLKRPEVIASGAVLLWLLLLGIAVCIYRRRKAGVHLGPGLYRYTSEDAILKHRMDHSDSPWLADTWRSTSGSRDLSSSSSLSSRLGVDPRDPLDGRRSLISWDPRSPGVPLLPDTSTFYGSLIAEQTSSPPVRPSPQTPAARRLPPKLTGTSSPWASSDSLCSRRGLCSPRMSLAPAEAWKAKKKQELHQANSSPLLQGSHPMEIWAWELGSRASKNLSQSPGPNTCSPREAPGAVVAWRALGPQLHRNSSELAARPLPPTPLSLRGAPSHDPQSQCVEKLQAPSSDPLPAAPLSVLNSSRPSSPQASFLSVPSPGSSNLSSSSLSSLEEEDQDSVLTPEEVALCLELSDGEETPTNSVSPMPRAPSPPATYGYISIPTSSGLADMGRAGGGVGSEVGNLLCPPRLCPTPTPSEGSLANGWGSASEDNVPSARASLVSSSDGSFLADAHFARALAVAVDSFGFSLEPREADCVFTGMWARPPPLEWT
What is the function of this protein?
Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning.  May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).  Involved in the maintenance of endothelial barrier organization and function (By similarity).
What are the official names of this protein?
Roundabout homolog 4.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ROBO family.
Protein: MURC_STRPZ
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSFISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAPIYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANLFVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPSKEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKIIKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUBD_METRA
Sequence: MSPSAPNTNELNSPVLETQPLAGDAALLHSSIAAGYEEIIRAPFDYLLNLPGKDVRSKMISAFNEWLCIPADKLEVIKRIVMLLHNASLLIDDIQDSSKLRRGLPVSHHIFGVPQTINAANYAYFLAQQELPKLGDPKAFEIYTEELLSLHRGQGMDIYWREASKCPTEEEYFSMVSHKTGGLFRLAIRLMQLASDKNWFVFHTRDFVPLVNVLGVIFQIRDDYLNLQSHAYTVNKGFGEDLTEGKYSFPIIHSIRSDPTNIQLSSILKQRTTDVDVKLFAVECIKATGSFEHCKEKIAELVAEARQLIKEMGNSVPGSAEAVDRVLDLIGLEPESS
What is the function of this protein?
Geranylgeranyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of the immunosuppressants subglutinols, meroterpenoids consisting of an alpha-pyrone (4-hydroxy-5,6-dimethyl-2-pyrone) moiety attached to a decalin core fused to a five-membered cyclic ether carrying a prenylside chain (PubMed:27189118).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase subA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:27189118).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase subD through the action of the prenyltransferase subC to yield a linear alpha-pyrone diterpenoid (PubMed:27189118).  Subsequent steps in the subglutinol biosynthetic pathway involve the decalin core formation, which is thought to be initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase subE (Probable).  The following cyclization cascade would be catalyzed by the terpene cyclase subB (Probable).  Lastly, the FAD-dependent dehydrogenase subF probably catalyzes the five-membered cyclic ether formation to complete the formation of subglutinol A (Probable).  Subsequent redox reactions appear to give rise to subglutinol C and D, however, it remains unclear which enzymes are responsible for these transformations (Probable).  SubD may have secondary function in the conversion of the identified subglutinols to subglutinol analog 45, which seems to be the major product of the cluster (PubMed:34863012).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase subD, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, Subglutinol biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: YNEK_ECOLI
Sequence: MVTPVSISNYISLPDDFPVRNIAPQVKEVLKDFIDALSTIICNEEWRTSLNINSATKKIFNNLDNLSYIQRTSFRGNDTLYNEKVQFKLTYPARNGRHKENIEFQVVINLSPIYLDNFRHDGEINIFCAPNPKPVTMGRVFQTGVERVLFLFLNDFIEQFPMINPGVPIKRAHTPHIEPLPSDHHTAADYLRQFDLLVLNFISRGNFVILPRLWNNSEVHRWFVNKDPNLITAILDITDSELKEDLLQSLMDSLGSNKHVLPEVCICFLSLLAEQESPHFQNLFLFFANMLLHYHQFMNPNESDLNDVLMPASLSDDKIIKHMARRTLKLFVKNETPPKVTHEDLVKNRPRSPVRPPIPATAKTPDLPERH
What are the official names of this protein?
Uncharacterized protein YneK.
Protein: YR838_MIMIV
Sequence: MDFSDLKKPGKVFFTITDEPEIKNGFQLKDGLNIIDSDKEVPQEFDCDYKPIVPNXLYFSEPKYICEYMAYGIYLREVYLPDDPKLKITRMKNFPCGKSMMYGANMIILGKKHKLSDPETYEYIEKCGGKLRYDGDNALLMAAENGYYEVVTYLINKGCDPRSDYDYALRSAAEKGHIDVVKLLLEKGADISSHNHWPLSYAALEGKFEMVKFLISRGADVRAKNYNPIKYALDGGHREIADYMLDLCPEIGSVSDDDTYDSDSSDYSEDDSESIN
What are the official names of this protein?
Putative ankyrin repeat protein R838.
Protein: PAND_MYCBO
Sequence: MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETI2_CHRSD
Sequence: MPKVGMEPIRRQQLIKATMAAIDEVGLAEATVMRIARHAGVSAGIISHYFGGKDGLLEATMRQILTDLSDAVAARRHALEDDSPRAHIGAIIEGNFDRTQVTGPAAKTWLAFWASSMHKPVLQRLQYVNDRRLYANLCHQFQRVMPKADARNAARGLAAMIDGLWLRGALTPEGLDAAEARYLAHTYLDQLLTHYGCYQDASTADFK
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI 2.
Protein: SLIB_CAPHI
Sequence: YADAIFTNSYRKVLGQLSARKLLQDIMNRQQGERNQEQGAKVRL
What is the function of this protein?
GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.
What are the official names of this protein?
Somatoliberin, Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: CDC42_CHICK
Sequence: MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKTRRCVLL
What is the function of this protein?
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.  In active state binds to a variety of effector proteins to regulate cellular responses.  Involved in epithelial cell polarization processes.  Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase.  Regulates cell migration.  Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia.  Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups.
What are the official names of this protein?
Cell division control protein 42 homolog, G25K GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell projection, dendrite.
Protein: TRI33_XENLA
Sequence: MADNKGGGGGGGETEGDASSNNNNNSNGAGETGSPGETESQAVEEPESAEKAPVAAVPTDTPAEENPAPSSSSVASSSATPASSSSSPLVVNLLDTCAVCKLSLQSRDTEPKLLPCLHSFCRRCLPEPERQLSVPGGTNGDIQQVGVIRCLVCRQECRQIDLVDNYFVKDASEAPNTDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHIITNKEDVSSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLESVTKERQIKLVQQQNDITGLSRQIKHVMTFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIENKPTTGFTPNVVVGQVPQGANHVNKPPAQINLAQLRLQHMQQQVYAQKQQQLQMRMAQPPGQHQRPSAPQVMHQQPPRLISMQSMPRNNMNCGPFQAHQMRMAQNAAQNAARMSGVPRHNGMQYSMMQPHLQRQHSNPGHAGPFPVVSVHNNTINPTSPTTATMANANRGPTSPSVTSIELIPSVTNPENLPSLPDIPPIQLEDAGSSNLDNLLSRYISLGHQLPQPTSNMNPSPAPSAMSPGSTGLSNSHTPVRPPSTSSTGSRGSCGSSSRTVERNSSFKSDPVKVKQEPGTEEEVCSFSGPVKQEKAEDGRRSACMLSSPESSLTPPLTTNVHLETDLESLAALENNVKTEPNNTSQSCRQSSHVSLVNGKSAVRNSMHRPPRGGGGGDGSNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGEWICTFCRDLNKPEVEYDCDNSQHSKKGKTVQGLSPVDQMKCERLLLYLYCHELSIEFQEPVPATIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQTPEDFVADVRLIFKNCERFNEMMKVVQAYADTQEINLQNDSEVAQAGKAVVLYFEEKLPAIYPDRTFQPLPEFEAEDDDGDVTDDSDDDDFVQPRRKRLKSEERPVHIK
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase for smad4.  Promotes ectoderm embryonic development at the expense of other germ layers.  Inhibits mesodermal differentiation.  Promotes neural development of the ectoderm.  Promotes smad4 alpha degradation via the ubiquitin proteasome pathway.  May act as a transcriptional repressor (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM33, Ectodermin, RING-type E3 ubiquitin transferase TRIM33, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLSA_BRUSU
Sequence: MSSSSDAIKAALEKGRAAGLSATGGKNADYIPFLASVPSDLFGLAVVTADGQTFKTGDADFAFAIESISKVFTLALVMEEIGPDSVREKVGADPTGLPFNSVIALELHNGKSLSPLVNAGAIATASLVPGDTADARWNNILECQCGFAGRRLKLSNEVNQSEQTTNFHNRAIAWLLYSAGTCYSDPMEAVDIYTRQCSTLVTATDLATMGATLAAGGVNPISGKRMVSAGNVAPILAEMTMEGLYTASGDWAYTVGLPGKSGVGGGIMAVVPGELAIAAFSPPLDPAGNSVKAMAAVAAVADSLGHNLYTTRGKVSS
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: Y746_MYCBO
Sequence: MPRAHDDNWDLASSVGATATMVAAGRALATKDPRGLINDPFAEPLVRAVGLDFFTKLIDGELDIATTGNLSPGRAQAMIDGIAVRTKYFDDYFRTATDGGVRQVVILAAGLDARAYRLPWPAGTVVYEIDQPQVIDFKTTTLAGIGAKPTAIRRTVYIDLRADWPAALQAAGLDSTAPTAWLAEGMLIYLPPDPRTGCSTTAPNSVLRAARSLPNLSRALWISTQAGYEKWRIRFASTAWTSTWRRWCIPANAATSSTTCAPRAGTLRAQCGPTYSGAMVCPFPPHTTTIRSAKSSSSAVV
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mb0746c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: LSHB_STRCA
Sequence: VPLGVPVALGVPPSRPPCRPVNVTVAAEKDECPQCLAVTTTACGGYCRTREPVYRSPLGGPAQQACGYGALRYERLALPGCAPGADPTVAVPVALSCRCARCPMATADCTVAGLGPAFCGAPAGFGPQ
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: 14331_SOLLC
Sequence: MALPENLTREQCLYLAKLAEQAERYEEMVKFMDKLVIGSGSSELTVEERNLLSVAYKNVIGSLRAAWRIVSSIEQKEEGRKNDEHVVLVKDYRSKVESELSDVCAGILKILDQYLIPSASAGESKVFYLKMKGDYYRYLAEFKVGNERKEAAEDTMLAYKAAQDIAVAELAPTHPIRLGLALNFSVFYYEILNASEKACSMAKQAFEEAIAELDTMGEESYKDSTLIMQLLRDNLTLWTSDMQEQMDEA
What are the official names of this protein?
14-3-3 protein 1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: MIAA_PSYWF
Sequence: MGDVDNLSLPTKLPDNAVVCLMAPTASGKTSLAYELYETGRFEIISVDSALIYKDMNIGTAKPTQSELEQYPHHLVDIIDPTQSYSVANFVSDTQQLVEQIHQRGKTPLLVGGTLMYYMALFNGLSPIPDTDPNVRAQVEAQRQQQGIEALHDYLSKIDPPLAERLPIGDTQRITRAIEVYQQTGKPLSYWQQLPKQALSDNPQQYWLGLAVMPDRAWLHERIALRLEMMWADGFFDEVGQLLTNYSLDAQMPSMRCVGYRQVIDYLIATDHPLISRLKINGQSVDNKGLEVNEAHKSIACQDMKNKALYATRQLAKRQYTWLRNLVASHQPSDTLQTSGAQTEQKVVHSFDTIQDAKAYLFSRL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: BETB_SERP5
Sequence: MSRFGLQKLYINGAYVDSTDGKTFNAVNPANGEVLAEIQSASAEDVNRAVASAASGQKVWAAMTAMARSRILRRAVDILRERNDELAALETLDTGKAMSETTAVDIVTGADVLEYYAGLIPSIEGQQIPLRDTSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAEIYTEAGLPDGVFNVVTGSGAEVGQYLTDHPGIAKVSFTGGVKTGKKVMANASGSTLKEVTMELGGKSPLIIFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPAALQAQFEAKILERVKRIRLGDPTDPQTNFGPLVSFAHMESVLRFIESGKNSGARLLCGGERVTEGEFAKGAYVAPTVFTDCRDEMEIVREEIFGPVMSILSYQSEEEVVRRANDTTFGLAAGVVTNDLTRAHRVIHQLEAGICWINTWGESAAEMPVGGYKQSGVGRENGLMTLEHYTQIKSVQVELGEYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: REV_FIVPE
Sequence: MAEGFAANRQWIGLEEAEELLDFDIATQMSEEGPLNPGVNPFRVPGITEKEKQNYCNILQPKLQDLRNEIQEVKLEEGNAGKRKRQRRRRKKKAFKRMMTELEDRFRKLFGTTSTTGDSTVDSEDEPPKKEKRVDWDEYWNPEEIERMLMD
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Probable protein Rev, 3'ORF, ART/TRS, Anti-repression transactivator, ORF4, ORFH, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: SAP5_ARATH
Sequence: MAQRTEKEETEFKVLETLTTTTTTLCTNNCGVTANPATNNMCQKCFNASLVSAAAGVVESGSILKRSARSVNLRSSPAKVVIRPREIDAVKKRDQQIVNRCSGCRKKVGLTGFRCRCGELFCSEHRYSDRHDCSYDYKTAGREAIARENPVVKAAKMVKV
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 5, AtSAP5.
Protein: MTND_LEPIC
Sequence: MATIVRQNGLTPIQETNEVKSFLKERGIDYDHWKVPHNASNLTDKEVLVDTEKEELLKKLDDRFETLKAKEGYQSRDLIVLHPNVSGLNEMLAKFDKVHYHTDEEVRYIVDGSGVFGFAFKDEKFLVHVYKDDFISVPRNTNHWFYLDDKKRIKAVRYFQDMSGWVPNYVEETNSLD
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: RSMC_SHESA
Sequence: MLTNPSQVIIRNQETLSQHRVLVLNHEADSLPKALLDVAQSVDALALDYHHYLHLAPQANAKLRCYFGHQLPHQDKYDTVIVYFPKAKPLAPYLFNLAAQHLVADGQLLVVGENKGGVKSLVKLLPKYFATGVKLDNARHCLLFGSSLIDTAPEIKLSDWTSQYQLSTPQGNITICNLVGVFSEKHLDQGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPTLSLECIDINAMALASCELTLAANGMTAKVYPSDGLAQTSGKFDGIISNPPFHDGLASTTSIAQRFVADSAKQLQSKGIWQIVTNRHLPYSDTIAAEFGQLTVPAENNKYKLYSFQQA
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_CLOPE
Sequence: MEAKMNKIDTNVVELEIKVDAKDFNEALKKSYNKNSKKFNIPGFRKGKVPMNMVKKFYGVEVLFDDAINACIDKTYGVALEENNVRPVDYPQIEVVEVGEGKDLVYKAKVTTYPEVTLGDYKGLEVEEVSYEVKEEDIEKQLADMQARNARVETKEEGTVENGNIAVIDFKGFIDDVAFEGGEGKDYPLEIGSGSFIDNFEEQLVGLKVGESKDVNVTFPEAYGKEDLNGKPAKFEVTVKEIKVKELPALDDEFAKEVSEFDTLEELKADLKEKAVKANELRAKREMEEKVINAVVDNAKVEIPEAMINREVENMVRDLEMRLGQQGLSLEQYYEFTGSTEDKMKSYMKENAERKVKTDLVMSAVTEAEAIEATEEELKAKAEEVAKMYSNGAETEKMVDLLLNAQRAALELDVKREKTLKMLFESLK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PER1_CAPAN
Sequence: GFEVIAQAKLGGQTYTVALGREMVALAGAHTVGFARMGNLPPSAGAQLEIR
What is the function of this protein?
Suggested to catalyze the deposition of the aromatic residues of suberin on the cell wall and thus play a role in cell-suberization.
What are the official names of this protein?
Suberization-associated anionic peroxidase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMG9_BOVIN
Sequence: MSESGHSQPGLYGIERRRRWKEPGPGGPQNLSGPGGRERDYIAPWERERRDGSEETSTAVMQKTPIILSKPPAERSKQPPPPAAPAAPPAPAPLEKPIVLMKPREEGKGPAATTSTSTPEGTAPPPPAAPVPPKGEKEGQRPTQPVYQIQNRGMGTAAPAAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRAYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSEEGAEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLMPFMDSETESETPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVKKSSALAEYSRLLA
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity).  Plays a role in brain, heart, and eye development.
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG9.
What is the protein family that this protein belongs to?
Belongs to the SMG9 family.
Protein: PROA_METCA
Sequence: MTAVSALRPAGPEAVAAYVDGLARRAREVGRILSRAETAAKNRALLAIAAALEESADALIEENRKDLEAGAAKGLDRAQLERLGVDAKRVQTMAVGLREIAALPDPVGEISGLTYRPSGIQVGRMRVPLGVIGIIYESRPNVTADAAGLCLKSGNACILRGGSEAIHSNRAIAACIRRGLEAGGLPADAVQLIETTDRAAVGALLAADEYVDIIVPRGGRSLIERVVAESRIPVIKHLDGICHVYIDDGADLAKARRIAINAKTQRYGVCNAMETLLVAAGIAPAVLPDLAALYRDKGVELRGCPETCRLVPDCVPATEADWDTEYLAPILAVRVVAGLDEAIEHIHRHGSGHTDAIVTEDYGRARRFLREVDSASVMVNASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTTQKFIVLGDGHVRI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.