PharMolix/UniProtQA huggingface dataset:
Protein: MT2_PONAB
Sequence: MDPNCSCAAGDSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: Y2536_ALKCK
Sequence: MVMMRDVWVNWFEGEENGYNVCPFHEWRSEDRIEVLDQVKLLKVDEKLMDYIEDQLLDLPMELLKEVFQKSYLRKNMSRIQLDYCFIATDGKRIIAVDTMGYKTPIRKSRLTPRQEQVVFETLTEQDVPYFQLEIPLPAKDYHLLSPSPAELAGLTRKERQLKQLLLMVLDQLQTTGSDAEIKYWCTEWDPLTYKKLQQKGRTEVWEQLLNGVRAGWSQRHYKLCEAMVKGHSFFEKLWELEHPERVK
What are the official names of this protein?
UPF0736 protein ABC2536.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: PDXJ_MARSD
Sequence: MPFLCVNVDHVATIRQARLGIEPDPVTAAAMCELAGAVGIIMHLREDRRHVQDRDIELISKTIQTEFHFEMAATEEMQQIALRIDPATVCLVPEKREELTTEGGLNCIGQEKRLTEYLAPLHEKGIGSSLFIDADADQIKAAKAIGAEYVEIHTGHFADAPTRSEQKAELTRIIDGIKMSQDLGLKVNLGHGLNYVNILDFADVPGICEYSIGHSIMSRAIYVGIDRAVRDMVEIIRNFAD
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBGN_GUITH
Sequence: MNNEILTLQVGKTGILTGNEFWKSLVREKNLLSDFSLGKNSPTNDNVFFEESNESFFIPRTIIFDLSERDFNYIMKSNYSKMYDKNRHFILNKNTGNSWLKGYYEGISNCNLVDNILRKRIEKMNSVKYFNVFNSINGGTGAGLSSYLIEYIRNNYPKSFINCCSIFPDLYGNTQVTFQPYNSVLSIAWQGLYCDSNIFFQNHAIENLLTKNQINNELSFRKVNYIIGKTISIIMNTLNHNFTLETLISPLIVNPYLNLFFSTINIDILLSKLRKKRPSMIENKTNQLNEISMNLDLKSGNYLSSIELSNRNFYKLFANSIYDKIFYDQTRFYSQLLNQYDSVIINNNVKKENYSSLTYLLNHTSFNPVIKKIIQNFELLKKRNAFLEYYCGEILLDEANTLFRESKDYILDIINNYDNILSYY
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma chain, nucleomorph, Nucleomorph gamma-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
Protein: LOLD_BLOPB
Sequence: MANIPLLQCIQLTKYYQRANFLIKVLNCITLSIQSNEMIAVVGASGSGKSTLLHLLGGLDKPTEGEIFFEGHALHKLTDNERSVIRNKRLGFVYQFHHLLSDFDVLENVAMPLLIGGIAFNQAKSRAQCVLELVGLKNHINSFPHELSGGESQRVTVARAIVNNPSLILADEPTGNLDQKNSDSIFQLLKKLNTYYGTTFLIATHDLDFAKKCHKILMISNGKIKLSQNDSFR
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CANB_CRYNJ
Sequence: MGAAESSMFNSLEKNSNFSGPELMRLKKRFMKLDKDGSGSIDKDEFLQIPQIANNPLAHRMIAIFDEDGSGTVDFQEFVGGLSAFSSKGGRDEKLRFAFKVYDMDRDGYISNGELYLVLKQMVGNNLKDQQLQQIVDKTIMEADKDGDGKLSFEEFTQMVASTDIVKQMTLEDLF
What is the function of this protein?
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase.  Confers calcium sensitivity.  Plays a central role in virulence and antifungal drug action.
What are the official names of this protein?
Calcineurin subunit B, Calcineurin regulatory subunit, Protein phosphatase 2B regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: TXH22_CYRSC
Sequence: LFECSFSCEQEKEGDKPCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Lethal neurotoxin that blocks neuromuscular transmission.  Acts cooperatively to potentiate the activity of huwentoxin-I.
What are the official names of this protein?
U1-theraphotoxin-Hs1b, U1-TRTX-Hs1b, Huwentoxin-2 form 2, Huwentoxin-II, HwTx-II.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSM3_ASHGO
Sequence: MSSVGPLEDEAAGTELGGSPADPATLTEIDPSAIQVRKTRTVVKLDCERLVSKKGLPYLLKNAPKHARISKRRDTYGNLCHVLQFYQLWAHELYPKAKFKDFVALCDRLGKTDRQLRAYRMQLIREELGLAAEGLDPPPQPLREHTGAGGSQPAGSVAQDTNTNADLSDDDLLYTTSRAAAASSTANPVPRSETPAALAGVDEAELLAQLAEMQRAAEEDVHESEDDEQLALMREMDEFM
What is the function of this protein?
Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Chromosome segregation in meiosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_DASMA
Sequence: MINMRKTHPLLKIINHSFIDLPAPSNISAWWNFGSLLGVCLMIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNHGWLLRNLQANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIIMALAVVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGLMLLLLMLLLLALFSPDLLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPLLHTANQRSMMFRPISQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASTLYFPLILILMPSAGLLENYMLEPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CH10_BACSU
Sequence: MLKPLGDRVVIELVESEEKTASGIVLPDSAKEKPQEGKIVAAGSGRVLESGERVALEVKEGDRIIFSKYAGTEVKYEGTEYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH1_NITOC
Sequence: MNATLTSLFNIFGILGTLLTLAALLIWIERRLLGFWQERYGPNRVGPFGILQVVADAIKLLTKEDWVPPFADKLVFILAPTVVVIATLLAFAVIPFTPYIGIIDLNIGLLFFLAMSSLSVYSVVLGGWASNNKYSLMGALRAAAQMLSYEVFMGLSLMGVVMLAGTFNLREIVAAQQDMWFCIPQFLGLVVFLIAGIAEAHRLPFDLPEAETELIAGFHTEYSGMKFGLFFVGEYLAILLISALIVTLFFGGWQGPWLPPLVWFFIKFSFFVLFFILLRAALPRPRYDQLMAYGWKLMLPLALLNLVITGAVVLALDGT
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 1, NADH dehydrogenase I subunit H 1, NDH-1 subunit H 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UGT13_HORVV
Sequence: METTVTAVSGTTSSSVGHGAGGGAARVLLLPSPGAQGHTNPMLQLGRRLAYHGLRPTLVATRYVLSTTPAPGAPFDVAAISDGFDAGGMALCPDPAEYFSRLEAVGSETLRELLLSEARAGRPVRVLVYDAHLAWARRVAQASGVAAAAFFSQPCSVDVVYGELWAGRLALPATDGRALLARGVLGVELGLEDMPPFAAVPESQPAFLQVSVGQFEGLDYADDVLVNSFRDIEPKEVEYMELTWRAKMVGPTLPSYYLGDGRLPSNKSYGFDLFNSDVECMDWLEKQMNSSVVLVSYGTVSNYDATQLEELGNGLCNSSKPFLWVVRSNEEHKLSEELKEKCGKIGLIVSWCPQLEVLAHRAIGCFVTHCGWNSTLEALVNGVPFVGIPHWADQPTIAKYVESAWGMGVRARKNKNGCLKKEEVERCIREVMDGERKDEYKKNAMNWMQKAKEAMQEGGSSDKHVAEFATKYSSI
What is the function of this protein?
Involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-D-glucose to the hydroxyl group at C-3, forming deoxynivalenol-3-O-beta-D-glucoside.
What are the official names of this protein?
UDP-glucosyltransferase UGT13248, HvUGT13248, Deoxynivalenol-UDP-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: DPO4_PSEE4
Sequence: MSLRKIIHIDCDCFYAAIEMRDDPRLAGRPMAVGGQPGQRGVIATCNYEARAYGVRSAMASGHALKLCPDLEIVKPRFEAYREASRDIHTIFRDYTDLIEPLSLDEAYLDVTDSQWFAGSATRIAEDIRRRVAQQLHITVSAGVAPNKFLAKIASDWRKPNGLFVITPDQVEEFVAQLPVARLHGVGKVTADKLARLGIDTCHALRDWPRLALVREFGSFGERLWGLARGIDERAVQNDSRRQSVSVENTYDHDLPDLNSCLEKLPELLSSLNERIARMDSSYRPDKPFVKVKFHDFSQTTMEQAGAGRDLESYRQLLSQAFARGGKPVRLLGVGVRLRDLRGAHEQLELFGDI
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA_METAC
Sequence: MIRLENVSYNYPDGTPALRNINIGIKKGEYIGITGKNGSGKSTLALHLNGLLRPQKGKVLVRGMDTGDFSKLQGIRKLVGIVFQNPETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLGKYRYRSPKTLSGGQGQCVALAGILTMEPDCLIFDEVTSMLDPDSGKAVLERVKRLHEKGKTIVYITHNLEELQAADRIIVMDRGKIVLEGTPENVLSDLSLRYLGLTPPSLIELAERLKNHGVAVPWEKTSSPSSFAEEICRLFLKT
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL4_CAUSK
Sequence: MKLDVINLDGGKAGSVDLDDAIFGIADIRGDILQRVVTWQLAKRRSGNHKIQVRNEVSRTGKKMYKQKGTGSARHGSRRAAQFVGGAKAHGPVVRSHAFDLPKKIRAMALRHALSSKAKSGSIIVLDTAVLTDPKTAALRANFDKIGLKNALVIAGPEVDGNFKLAARNIPNIDVLPNAGLNVYDVLRRHTLVLTKDAVEAISARFAEKEAA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS6_NITMU
Sequence: MRHYEIVFIVHPDQSEQVSAMIERYRNIVTARNGQVHRLEDWGRRQLAYLIQKVHKAHYVLMNIECDQETLDELEHAFKFNDAILRHLTLKMDEPVTAPSPMMREEKAKSAPQPAEEAKETTLAT
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SMG_PECCP
Sequence: MFDVLMYLFESYIHNETEMRVDQDTLTDDLTRAGFDRNDIYSALSWLEKLADIQEGQTAPLYLANDPLAMRIYTQDETLRLDAECRGFLLFLEQIQVLNLETREMVIERVMALETQEFDLEDLKWVILMVLFNVPGCENAYQQMEELLFEVNDGYVQ
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: YCF70_SACOF
Sequence: MVLYALFYVFLVLFIFFDSFKQESNKLELSGKEERKLGNGGDRLTRDFLDPLYEEFEESSSESSDVNFHQVNLSIRICFSF
What are the official names of this protein?
Uncharacterized protein ycf70, ORF81.
What is the protein family that this protein belongs to?
Belongs to the ycf70 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSF3_FELCA
Sequence: KLMALQLLLWHSALWMVQEATPLGPTSSLPQSFLLKCLEQVRKVQADGTALQERLCAAHKLCHPEELVLLGHALGIPQAPLSSCSSQALQLTGCLRQLHSGLFLYQGLLQALAGISPELAPTLDMLQLDITDFAINIWQQMEDVGMAPAVPPTQGTMPTFTSAFQRRAGGTLVASNLQSFLEVAYRALRHFTKP
What is the function of this protein?
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.  This CSF induces granulocytes (By similarity).
What are the official names of this protein?
Granulocyte colony-stimulating factor, G-CSF.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_CHLPD
Sequence: MDNLQNVLKIGLPKGSLQDSTLELFANAGFHFSVQSRSYFPSIEDDELEAILIRAQEMAHYVELGAFDVGLTGKDWIIETDADVVEVADLVYSKASMRPVRWVLAVPESSAIKSVKDLEGKHIATEVVNITKKYLARNGVNASVEFSWGATEVKPPDLADAIVEVTETGSSLRANKLRIVDTILESNTKLIANKASWNDSWKREKIENMAMLLQGAINAQGKVGLKMNAPKAALQNIAAIIPALRQPTISNLADENWVALEVIVSEKTVRKLIPELKRAGAEGIFEYNINKLID
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_STAAC
Sequence: MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYKYLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKEPVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLRGIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSQIK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D104A_HYLLA
Sequence: MRRLVLLLTISVLLYQDLPVRSEFEWDRICGYGTARCRNKCRSQEYRIGRCPNTFACCLRKWDESLLNSTKP
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Beta-defensin 104A, Defensin, beta 104, Defensin, beta 104A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATF3_MOUSE
Sequence: MMLQHPGQVSASEVSATAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVNNRPLEMSVTKSEAAPEEDERKRRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
What is the function of this protein?
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (PubMed:11916968).  Represses transcription from promoters with ATF sites (PubMed:11916968).  It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, Transcription factor LRG-21.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_TREDE
Sequence: MQIGKYSLGDPIAAIATALSPAALGIVRTSGEGAIDLASAIFSKPKKLKEAQGNSILHGWVLDPESKKEVDEVTVCVYREPKSFTGEDSVEFICHGGTAVVLKIYRLLIENGFRAAEGGEFTFRAFANGKADLTRAEAVNEIINSKTDINIELAAGRLSGNLFSGIEEIKHELTAVIAAADVEIEYPEDEETSQGAFSPDLILRIIEPLKDLADSWAAEKIFIQGAKVVLAGKTNAGKSSLFNALLKEDRAIVSDIHGTTRDWLEASLNFNGIPVSLYDTAGIRYTQDSIEAIGVERSLEMSRNADLILYLCDPKDILSAGSLNKDDSEFIKNAKAPVITVITKEDLLDTESKEKIKEILKAEKIAEPIIISSKASNGIKALSEKAYSVLAKNTGSSGFSKTASLGSERQRDAVQKALDVLQTAYQNSLEGFPLDLIVEDLEEALSFLGEITGEVRSDDILDKVFSGFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAJ_CITSI
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MNMA_FRAP2
Sequence: MQNNKIIVGISGGVDSSVSALLLKQQGYDVTGVFMKNWEEDDTDEFCSAEQHIADAQAVCDSIGIPFKKINFAAEYWDNVFEHFLTEYKAGRTPNPDILCNKEIKFKAFLSYVHLLGGDYIATGHYARTKVIDDGSVQLVKGLDDSKDQTYFLYTLGQEQLKQTMFPIGDIEKSRVREIAKENNLVTFDKKDSTGICFIGERKFKDFLSKFLPAQKGEIHDENGIKIGMHDGLMYYTIGQRQGLGIGGVKNRPEIPWFAAQKDLENNVLIAVQGHDHPMLFKDTLQAIDLSWVAGSAPADSFRCSAKVRYRQKDQPCSVEVNNDGSVNVVFDEPQRAITPGQSVVFYDNDVCLGGGIII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSM1_ZYGRC
Sequence: MTKKLSLELRQTRKPIQTACGFCHEKHLQCDVGRPCQNCRKRNIASFCRDKVKRRRKRKRSDASNFDKDEAATQTLNFNTVNPGEGSSSAMTQDEKNTGTTTATTTRTTTNFRSESKASSSTENISRAMKDPADTIIANSLLDKPTIGDTDDTGWGFGSIWTNDEYMTLNDLTSFASESMPNQLGPIEEQRSPRRTLGEPLARRYDSSQPFQYLNFGSKLHKTDSRPYISLEQPGNVPSIPAFTMNKGSNDEDASPQQKESQQMQLWQQQASQLQQQASQLQQQASQLQQQRTQQNEPVSEWTPFQLRLLIKTPKDLFDKKNLVKPHNYRKAYKDLLECLHKMFLGSYYRRQNGRWRPVSDDEDQMRRRLMRKEQLQHIAKSIGELYMPKFVALTSNMIEEDLLLQELVLQRSLLELENMSKLVNCTPICIWRRSGEICFVSNEFCSLTGFYKREILDQRRFIVEFMDHQSVVSYYDLFHEHLAFGPKDSTRTILNKDQAVYTECNLLLNNGSYLKCACCLTARRDAFNISLLLMGQFLPIFDVQ
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.
What are the official names of this protein?
Glucose starvation modulator protein 1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HDAC3_XENLA
Sequence: MAKTVAYFYDPDVGNFHYGTGHPMKPHRLSLTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATLLNNKNCDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRHLFQPVIKQVIDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVQYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDETISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTVFESLKMLNHAPSVQIHDVPSDILNYERTDEPDPEERGGEDNYSRPEASNEFYDGDHDNDKESDVEI
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates.  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression.  Also functions as deacetylase for non-histone targets.  In addition to protein deacetylase activity, also acts as protein-lysine deacylase by recognizing other acyl groups: catalyzes removal of (2E)-butenoyl (crotonyl) and 2-hydroxyisobutanoyl (2-hydroxyisobutyryl) acyl groups from lysine residues, leading to protein decrotonylation and de-2-hydroxyisobutyrylation, respectively.
What are the official names of this protein?
Histone deacetylase 3, HD3, Protein deacetylase HDAC3, Protein deacylase HDAC3.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LEXA_SHEWM
Sequence: MRPLTPRQAEILELIKCNIAETGMPPTRAEIAKRLGFKSANAAEEHLKALAKKGCIEIIPGTSRGIRLAQTEELEEQGLPLIGQVAAGEPILAQEHVEQHYQVDPNMFHPSADFLLRVRGDSMKDIGILEGDLLAVHKAEQARNGQVVVARVEDDVTVKRFEKKGSTVYLHAENEDYSPIVVDLTNQSLSIEGLAVGVIRNGDWQ
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.