PharMolix/UniProtQA huggingface dataset:
Protein: MSRP_RUEPO
Sequence: MAHRWINDLTPADITPRGAWMNRRQVMAGMAGAGLAAFAGSAQAETLEPNSWEEITSYNNFYEFGTGKDDPAAYAHLLKTVPWSIKIDGMVERPGDYDFQDILSEMTIEERIYRFRCVEAWSMVIPWNGFELADLLAMAGVQEGAKYVAFETLYRPEEMPGTRYPVLEWPYREGLRLDEAMHPLTLMATGIYGKPLPNQNGAPLRLVVPWKYGFKSIKSIVRITLTDREPPASWNMAIPNEYGFYSNVNPEVNHPRWSQASERRIGGGLFAKRQPTLMFNGYEKEVAGLYQGMDLAKYF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: TRPC_RHOPS
Sequence: MSDILNKIEAYKREEIAAAKRERPLAALQAAARAAPPPRGFVSALRAKLADGDYALIAEIKKASPSKGLIRPDFDPPALAKAYQQGGAACLSVLTDTPSFQGHLDYLVAARAAVSLPALRKDFMYDTYQVVEARAHGADCILIIMAALDDSEARDIEDAALDLGMDVLLEVHNHAELDRALALRSPMIGVNNRNLRTFEVTLATSEALAPLIPSDRLMVGESGIFTPDDLARLARVGMSTFLVGESLMRQQDVAAATRTLLARAA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LEXA_CERS4
Sequence: MLTRKQMELLDFIKTRMDRDGVPPSFDEMKDALDLRSKSGIHRLITALEERGFIRRLAHRARAIEIVKLPEAMERAGFSARAAKAAAAPLPKGAVTVETAGALDLPLMGRIAAGLPIEAINGGPQSVTVPGMMLSGRGQHYALEVKGDSMIAAGINDGDIVVIREQQTADNGDIVVALVADHEATLKRYRRRGGMIALEPANDSYETQVYPEQMVKVQGRLVGLIRSY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Has been shown to bind to the direct repeat sequence 5'-GTT-N(7)-GTTC-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RR18_CHLVU
Sequence: MAGIQQKRKTIKSFKTRRKVVPVLIPKKGQAVISNTGEPASRYIIDYKNTQLLVKFISPQGKILSRRATGLTAKQQRIMANAIKRARMGGLVPFVNYELGSKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CE3E_HYPCU
Sequence: MNFSRILFFVFTCFVALASVSGAPEPRWKFFKKIERVGQNVRDGLIKAGPAIQVLGAAKALGK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Hyphancin-3E, Cecropin-A1, Hyphancin-IIIE.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCD_RHOP2
Sequence: MNWLTNVVRPKIRNILRRETPENLWIKCPDTGQLVFYKDVEQNQFVIPGSNYHMRMGATARLRSVFDNETWYDVALPEVTADPLKFRDERKYVDRIKDARAKTGAHDAVKVGYGKLEGLGVVAAVQDFDFMGGSLGMAAGEAIIRGLELAVEKHAPFIMFAASGGARMQEGILSLMQMPRTTVAVQLLREAGLPYIVVLTNPTTGGVTASYAMLGDIQLAEPGALIGFAGARVIEQTIREKLPDGFQRAEYLRDHGMVDMVVHRHELRPTLARLCRILTKTPLPAVEEPAVVDDDAQDIEAVATEIVATPPEPAPPPAAPQA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_CLOBL
Sequence: MSKEDNVINSFEEQANELMKERFQKLKELQSNGKDPFDVYKVERTHTSKEVKDNYEDLEGKTVTVAGRLMSKRVHGKAGFSDIHDRYGKIQLYIKINDVGEEKLKEYKTFDIGDIISVTGTVFKTKTGETSIHITDFQLVCKSLRPLPEKWHGLKDPDLRYRQRYVDLIINQDVRDTFIKRTAIIKSMREFLDNRGFLEVETPILSPIAGGAAAKPFITHHNALDIDMYLRIATELYLKRLIVGGFEKVYEIGKNFRNEGIDIRHNPEFTAIELYEAYADYNDMMEITENMIAYICEKVLGTTKVEYEGAEIDFTPPWRRLTMVDAVKEYAGVDFNIIKNDIEARTIAKEKHIEFKKELKDCTKGDVLIGLFEEFCEDKLMQPTFICDYPVENSPLTKKKRGNEAFTERFEGFVFGREVCNAYSELNDSIVQKERFMQQLKERELGDDEAYMMDDDFITSLEVGMPPTGGLGIGIDRLIMFLTDTHSIRDVILFPTMKPQPNNQ
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SALTY
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: JUNO_MOUSE
Sequence: MAQWWQILLGLWAVLPTLAGDKLLSVCMNSKRHKQEPGPEDELYQECRPWEDNACCTRSTSWEAHLEEPLLFNFSMMHCGLLTPACRKHFIQAICFHECSPNLGPWIQPVVPNGQEEQRVWGVPLCQEDCEDWWRACHSSLTCKSNWLHGWDWSEEKKHCPAHEPCLPFSYHFPTPDDLCEKIWNNTFKASPERRNSGRCLQKWFEPTLSNPNVEVALHFAGSALAPQLSYTLPAFSLCLLFHP
What is the function of this protein?
Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization (PubMed:24739963, PubMed:26859261, PubMed:27309808, PubMed:27416963).  The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:24739963, PubMed:26859261, PubMed:27309808).  The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PubMed:24739963, PubMed:26859261, PubMed:27309808).  Does not bind folate (PubMed:24739963).
What are the official names of this protein?
Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, Folate-binding protein 3, IZUMO1 receptor protein JUNO.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
What are the subcellular locations of this protein?
Cell membrane; Lipid- anchor, GPI-anchor. Note=GPI-anchored at the oolemma.
Protein: CARB_METB6
Sequence: MPKRTDIKKVLLIGSGPIQIGQAAEFDFSGSQACRSLKEEGIEVVLVNSNPATIMTDPDMADQIYIEPLRANIIAKIIEKERPDGILSGMGGQTGLNLTAELAEMGALKGVEILGTPLEAIYKGEDREKFRDLMNEIGEPVPKSIVLNTLSQIDDAIAKIGLPAVVRPAYTLGGAGGGIGRTREELTRIVELGLSRSRIHQVLIEESVMGWKELEFEVMRDSTDTCIIVCSMENVDPMGIHTGESVVVAPILTLRDDEFQMMRSAAIHIIRALDVQGGCNIQFAFKDGDYRVIEVNPRVSRSSALASKATGYPIARVAAKIAIGLRLDEIKNSVTGCTAASFEPTIDYIVVKVPRWPFDKFKGADRTLTTSMKSTGEVMAIGRTLEESFMKAKRSIDTDVRTHTSPSEIRMILSRPTDERFHCLFDAFRQGFTLDEIAGLTSIVPFFLEKIKNIVDLEKRLAAGCTDEDIFLAKRYGFANTEIAALTGRGADTIEALVGAPAYKMVDTCAAEFPASTPYFYSTREGTSEIVRDKKQKILILGSGPIRIGQGIEFDYCTVHAVKALREEGVEVHIVNNNPETVSTDFDTSDRLFFEPMLLEDVTNILMTDEYYGVMVQFGGQNAVNLAVPLEKELKRRGMCTRILGTSPDAMDIAEDRDRFSVLLTTLQIPSPANSSAYSEAEAREKAERIGYPVLVRPSYVLGGRAMEIVHNTAELETYMKEAVRVSQHHPVLIDSYLRNAIELDVDAVCDGKEVLIGGIMEHIEQAGIHSGDSACVIPTQSLSPEVIATVREYTKKIALGLGVVGLVNIQMAVKDNVVYILEANPRASRTVPFVSKATGLPIAKIAAKVMIGKKLCDLGFHEAKIRHVAVKEVLLPFNKLAGVDTILGPEMKSTGEVMGIDYDFGLAFYKACISADNELPLKGNVFVSVNIGQKDEVIPIARRLRDLGLTLYGTEGTVDYLHEAGVEAHLVRKVQEGSPNVLDMMHHGEIRLIINTPQDRQSRQDHYQIMRAAVDFQIPYITTLQAARAAALAIDAIKREKITLEPLSHYLR
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: ARGR_STAAE
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COR15_PAPSO
Sequence: MESNGVPMITLSSGIRMPALGMGTVETMEKGTEREKLAFLKAIEVGYRHFDTAAAYQTEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLDYLDLYLIHHPVSLKPGKFVNEIPKDHILPMDYKSVWAAMEECQTLGFTRAIGVCNFSCKKLQELMATANSPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAVGAAWGTKAVMHSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEARMKENLKIFDWELTAEDMEKISEIPQSRTSSAAFLLSPTGPFKTEEEFWDEKD
What is the function of this protein?
Reduces codeinone to codeine in the penultimate step in morphine biosynthesis.  Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as cofactor, and morphine and dihydrocodeine as substrate during oxidative reaction with NADP as cofactor (By similarity).
What are the official names of this protein?
NADPH-dependent codeinone reductase 1-5.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex.
Protein: PYC1_MICDP
Sequence: MARLFKVTACVPSQTRIRTQRELQNTYFTKLVPFENWFREQQRIMKMGGKIVKVELATGKQGTNTGLL
What is the function of this protein?
Rod linker protein, associated with allophycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 7.8 kDa linker polypeptide, allophycocyanin-associated, core, LC 7.8.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=This protein occurs in the rod, it is associated with allophycocyanin.
Protein: RL24_LEPCP
Sequence: MNKILKGDEVIVLTGRDKGKRGKIAVRVDEDHVLVDGVNVVKKHVRPNPLKGTTGGIVDKTMPIHQSNVAIYNPASGKADRVGIKLLADGKKVRVFKSSGEEIKA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: LUXS_HAEIE
Sequence: MPLLDSFKVDHTKMNAPAVRIAKTMRTPKGDNITVFDLRFCIPNKEILSPKGIHTLEHLFAGFMRDHLNGDSIEIIDISPMGCRTGFYMSLIGTPNEQEVSEAWLASMQDVLGVQDQASIPELNIYQCGSYTEHSLEDAHEIAKNVIARGIGVNKNEDLSLDNSLLK
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y2655_ALISL
Sequence: MEKKPNKRIKGEYYELMAKRYLETHQLTFIERNFYSKTGELDLIMRDRDSFVFVEVKYRASSNYGSAQEMVTWQKQRKLQRTALFWLMKNGLSVEHTSFRFDVVAIHSQGQDINWIKNAIVEG
What are the official names of this protein?
UPF0102 protein VSAL_I2655.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NOC_BACC3
Sequence: MKNTFSRLFGFGDKESEFELQDESHEEIDKKVYEEIQEIPIVNITPNRYQPRTVFDDARIEELALTIRTHGLIQPIVVRQYEDDKYEIIAGERRFRAATKLGWEKVPAIIKNLNDTETASVALIENLQREELTAIEEAVAYQKLIELHNLTQEALAQRLGKGQSTIANKLRLLKLPEEIKSALLEKSITERHARALIPLKNEELQLKVLQEIVEKQLNVKQTEERIAKLLEEAKPKRKAKQKAVSRDTRIAMNTIRQSLQMVADSGLNVNSEEEEFDEYYQITIQIPKKK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL12_PYRHO
Sequence: MEYVYAALLLHSVGKEINEENLKAVLQAAGVEPEEARIKALVAALEGVNIDEVIEKAAMPVAVAAAPAAAPAEAGGEEKKEEEKKEEEEKEEEVSEEEALAGLSALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.  The stalk complex of P. horikoshii binds to E. coli large subunits and confers on them the ability to interact with eukaryotic elongation factors.  Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes.
What are the official names of this protein?
50S ribosomal protein L12, Acidic ribosomal protein P1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: PURT_BACTN
Sequence: MKKILLLGSGELGKEFVISAQRKGQHVIACDSYAGAPAMQVADEFEVFDMLDGEALERVVEKHHPDIIVPEIEAIRTERLYDFEKEGIQVVPSARAVNFTMNRKAIRDLAAKELGLKTANYFYAKTLDELKEAAAKIGFPCVVKPLMSSSGKGQSLVKSADELEHAWEYGCSGSRGDIRELIIEEFIKFDSEITLLTVTQKNGPTLFCPPIGHVQKGGDYRESFQPAHIDPAHLKEAEEMAEKVTRALTGAGLWGVEFFLSHENGVYFSELSPRPHDTGMVTLAGTQNLNEFELHLRAVLGLPIPGIKQERIGASAVILSPIASQERPQYRGMEEVTKEEDTYLRIFGKPFTRVNRRMGVVLCYAPLNSDLDALRDKAKRIAEKVEVY
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: VP24_MABVM
Sequence: MAELSTRYNLPANVTENSINLDLNSTARWIKEPSVGGWTVKWGNFVFHIPNTGMTLLHHLKSNFVVPEWQQTRNLFSHLFKNPKSTIIEPFLALRILLGVALKDQELQQSLIPGFRSIVHMLSEWLLLEVTSAIHISPNLLGIYLTSDMFKILMAGVKNFFNKMFTLHVVNDHGKPSSIEIKLTGQQIIITRVNMGFLVEVRRIDIEPCCGETVLSESVVFGLVAEAVLREHSQMEKGQPLNLTQYMNSKIAI
What is the function of this protein?
May act as a minor matrix protein that plays a role in assembly of viral nucleocapsid and virion budding (PubMed:16227263).  Unlike Ebola VP24, mVP24 has no measurable impact of host dendritic cell function (PubMed:26962215).
What are the official names of this protein?
Membrane-associated protein VP24, Marburg VP24, mVP24.
What is the protein family that this protein belongs to?
Belongs to the filoviridae membrane-associated protein VP24 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Note=In virion, localizes on the intravirional side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and to the plasma membrane where budding takes place.
Protein: RBM4B_MOUSE
Sequence: MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRTGRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASAYNYAEQTMSHLPQVQSSAVPSHLNSTSVDPYDRHLLQNSGSAATSAAMAAAASSSYYGRDRSPLRRNAAVLPAVGEGYGYGPESEMSQASAATRNSLYDMARYEREQYVDRTRYSAF
What is the function of this protein?
Required for the translational activation of PER1 mRNA in response to circadian clock.  Binds directly to the 3'-UTR of the PER1 mRNA.
What are the official names of this protein?
RNA-binding protein 4B, RNA-binding motif protein 30, RNA-binding motif protein 4B, RNA-binding protein 30.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL9_GEOSL
Sequence: MKVILKENVENLGHIGDIVKVAPGYARNYLIPRNFAIEATEKNAKALEHAKRQLEYKRNKVLEQARLLVAKIEGLSLSISHQAGEEGKLFGSVTNMELAELLKAQGVEIDRKKIVLAEPIKHVGEFTAVVKVHPEVAANLKVVVTKAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NIFD_AZOVI
Sequence: MTGMSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKCIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGLIGDDIESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLEEMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKKCEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDDVTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFREMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWEASEGAEKVAASA
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: SPEE_SALPK
Sequence: MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDYN_BOVIN
Sequence: MVWQGLVLAACLLALPSVTADCLAQCSLCAVKTQDGPQPINPLVCSLECQAALQPAQEWERCQGLLSFLTPFTVGLNGKEDLKSKTVLEESSSEPAKHIRPYLKELEKNRFLLSTPAEKNALSSSLVEKLRGLSGRLGEDAESELMGDAQLNDGALEAEARDSNEEEPKEQVKRYGGFLRKYPKRSSEVTGKEAGEGEGGEVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQEDPSAYYEELFDV
What is the function of this protein?
Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
What are the official names of this protein?
Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTD_YERPS
Sequence: MSQHVMFNAVLSSHPALFIQGEWRIGNGVSFEKQDPMSQQRLWQARAADHTDVTLACHAARAAFPAWARASLEQRATVIQQFAALLEQHKQSLARTISLETSKPYWETLTEVQAMIGKVAISLQAYQTRTGHSQTPMGDSMSVLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPWTAEETVKLWQEAGIPDGVLNLVQGGRETGEALAAQPDIDGLLFTGSAHTGYHLHRQLAGQPEKMLALEMGGNNALIVEQVKDRDAVVNLAIQSAFISAGQRCTCSRRLLVKTGAEGDAFLLRFTAVAQALRIGRWDEQPAPFMGAVISSQAAERMLAAQQHLLLLGGESLLNMTRPDSQSALLTPGIIDITNISEVPDEEYFGPLVSVIRYTDFTEALKIANQTRFGLAVGLVSEDRQQFEQLLLEARAGIVNWNKPLTGASSAAPFGGVGASGNHRPSAFYAADYCAWPMASLECEHLTLPATLSPGISFDLPKV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: PUR7_STREM
Sequence: MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEGKGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSKRFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAYLKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLGSLTQAYETVLERLRALDQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYP_SHEB8
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWEKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGMMRSREFLMKDAYSFHLDVDTMNETYEAMYNAYSNILTRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPVPTEPRGAATEELRLVDTPNAKTIAELVEQFDLDITKTVKTLIVVGASEATPLVALIVRGDHELNEVKADKLDLVASPVEMASEALIRDAIGAGPGSLGPIGLNIPIVIDHSVSVMSDFAAGANVDDKHYFGINWERDLPTAQVADIRNVVEGEPTPDGLGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIIWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLNEAGIDVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDIPFDQLLDFLKNAVKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.