PharMolix/UniProtQA huggingface dataset:
Protein: SMD1_YEAST
Sequence: MKLVNFLKKLRNEQVTIELKNGTTVWGTLQSVSPQMNAILTDVKLTLPQPRLNKLNSNGIAMASLYLTGGQQPTASDNIASLQYINIRGNTIRQIILPDSLNLDSLLVDQKQLNSLRRSGQIANDPSKKRRRDFGAPANKRPRRGL
What is the function of this protein?
lays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:8430095).  Also binds telomerase RNA and is required for its accumulation (PubMed:10490028).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D1, Sm-D1, snRNP core protein D1.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HEM3_BURMS
Sequence: MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAASAQAQKGGA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YXER_BACSU
Sequence: MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPLALSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPQAGLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCLIGGLCAGFDIGMIGKNLLIPSLLSAVIAFGLWRYTDRMIQLFHLFGKAVSMVAIIGLAAVSVETMTGIVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKCLHLDETATAGLVTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKLAGGVTAAAAAAWMTPAQSAKQQKRISASHS
What are the official names of this protein?
Uncharacterized protein YxeR.
What is the protein family that this protein belongs to?
Belongs to the EutH family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RTCA_NOSP7
Sequence: MIEIDGSYGEGGGQVLRTSLSLAAITGEPIRIAGIRAGRKKPGLAAQHLTAVRAAGRICNAQLRGDALGSMLLEFIPGSAVQAGIYTFDVSKAQEGGSAGAIALVLQTILLPLALATGNSQVTLKGGTHVNFSPTVTYIEQVYLPILQRMGVEAQVKLGAWGWFPQGGGEIELQVIGGTQLGGINLLERGELQQVRGIAAVTELPSHIPQRMANRAENLLREAHLKVRVQTLREKGVAPGAGIFLTAEYQNSLTGFGGFGRLRLSAETVAEIACQQLLEFHYTGAAVDEHLADQLLLPATLASQESQYQVAEVSRHLITNAAVIEQFGLAQIRVNEADKIVSVKSLTS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARL_BACSH
Sequence: MKLARKIKNRLFRSKKKTQKENTAVIVHPADNRVFSLFDKTKRIEENQQVPVRKISEFSWNGSILKIAGYMYIKGLPLQKEDQVRKRLLLVNNGVLFTAVSLRDIPVDQLSIDTSNVPGAYKWAGFSQQINFSKLMNDKPLPQGEYKLFLEIEAVDDQNVKHQEVHTVGNVSNFLSNDVYATKMEFHSAKKLMKFNLIVNYDEGEKTINLSCNKLQEIDPSLLELDTGKEANRFIRKLNTSLFHFAYDVFRLLPIKSNKIVFASDSRLDVTGNFEFVYEELLKREENFDFKFFLKSSIRDRKSLSELMSMAYHFATSKIIFIDDFYPIIYPLKIRKNADLVQLWHAVGAFKTFGYSRIGLPGGPSPHSKNHRNYTKVIVSSENIRKHYAEGFGVDIENVIATGVPRTDFFFDEAKKAFVKERLYTEYPFLKDKKVILFAPTFRGNGQQSAHYPFEVLDFDRLYRELKDEYIFLFKIHPFVRNDANIPYQYSDFFYDFSSFREINELLLVTDVLITDYSSVCFEYALLNKPMIFFSYDVDDYIRKRDFYYDYFDFIPGPLAKTSDQMISIIKEEKYNFEQIDSFVHYFFDDLDGKASERVVDQIVFPQEEEPVDDKVLKR
What is the function of this protein?
Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the glycerol phosphate attached to the disaccharide linkage unit.  Synthesizes polymers of up to 40 ribitol phosphate units in length.
What are the official names of this protein?
Teichoic acid poly(ribitol-phosphate) polymerase, Poly(ribitol phosphate) polymerase, Tar polymerase.
What is the protein family that this protein belongs to?
Belongs to the CDP-glycerol glycerophosphotransferase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BG1_ARATH
Sequence: MDLRFLASLTLLLGLFFVNTNPTGGQVGVCYGRNGNNLPSPAETIALFKQKNIQRVRLYSPDHDVLAALRGSNIEVTLGLPNSYLQSVASSQSQANAWVQTYVMNYANGVRFRYISVGNEVKISDSYAQFLVPAMENIDRAVLAAGLGGRIKVSTSVDMGVLRESYPPSKGSFRGDVMVVMEPIIRFLVSKNSPLLLNLYTYFSYAGNVGQIRLDYALFTAPSGIVSDPPRSYQNLFDAMLDAMYSALEKSGGASLEIVVAETGWPTGGGTDTNIENARIYNNNLIKHVKNGTPKRPGKEIETYLFAIYDENQKPTPPYVEKFWGLFYPNKQPKYDINFY
What is the function of this protein?
May play a role in plant defense against pathogens.
What are the official names of this protein?
Probable glucan endo-1,3-beta-glucosidase BG1, Beta-1,3-glucanase 1, AtBG1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_ANADF
Sequence: MARIRLGKVVRAVGLKGHLGVAGSEGALATVRRIALRREGEPEPPLQEVLEARPQGRLWAVRIEGVSDRTSAEAWVGAEVLALREDLPEAGEARHYWADLEGLPVVTVAGAAIGTVTGLYETGGVDVLVVTTEEGGEKLVPLAPYVEVDVAGRRVVVDPPEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BACVZ
Sequence: MLYYLIALFIIIADQLTKWLVVSHMELGQSIPVIDQVLYITSHRNTGAAWGILAGQMWFFYVITIAVIIGIVYYIQRYAKGQMLLGISLGLMLGGAAGNFIDRAARQEVVDFIHVIIVDYHYPIFNIADSSLCVGVILLFIHMLFDSGKKKEQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPOL_HBVC4
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEDLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPEWQTPSFPHIHLQEDIINRCQQYVGPLTVNEKRRLKLIMPARFYPKLTKYLPLDKGIKPYYPEHAVNHYFKTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHGRLVFQTSTRHGDESFCSQSSGILSRSPVGPCVRSQLKQSRLGLQPQQGSLARGKSGRSGSIRARVPPTTRRSFGVEPSGSGHIDNRASSTSSCLHQSAVRKTAYSHLSTSKRQSSSGHAVELHHISPSPARSQSEGPIFSSWWLQFRNSKPCSDYCLTHIVNLLEDWGPCTEHGEHNIRIPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGSTHVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLPRYVARLSSTSRNINHQHGTMQDLHDSCSRNLYVSLLLLYKTFGRKLHLYSHPIILGFRKIPMGGGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTSITNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQEHIVLKIKQCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLHLYPVARRTALCQVFADATPTGWGLAIGHRRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTYFVYVPSALNPADDPSRGRLGLIRPLLHLRFRPTTGRTSLYAVSPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: PYRH_FUSNN
Sequence: MESPFYKKILLKLSGEALMGDQEFGISSDVIASYAKQIKEIVDLGVEVSIVIGGGNIFRGLSGAAQGVDRVTGDHMGMLATVINSLALQNSIEKLGVPTRVQTAIEMPKVAEPFIKRRAQRHLEKGRVVIFGAGTGNPYFTTDTAAALRAIEMETDVVIKATKVDGIYDKDPVKYPDAKKYQTVTYNEVLAKDLKVMDATAISLCRENKLPIIVFNSLDEGNLKKVVMGEHIGTTVVAD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCA8_SCHPO
Sequence: MDNSRDKIHILGAVSDTFQEVQHPCSILKYKVYFVTTDTFYCKYLTASFTGLKKFPTERQLPLECHFNHIDWDLGNNFKVKEGVFYTFDIIAPLPRCTPRTIVTQEGSISYKLTVKLYTEDDCRMPKSANVPVVVPFTLNPDRIPESQHIRYGAPLNDACFTSLSMKSSKYSFLTAFFKYPQQCYKGPGCVCPLLIDLESEDADVLSSTPGSAGTDDPHIDPIAINSQDSQFIFQDRLPRLSNDCDMKGRSSLSRTSSPVVEKKLKRYYIRVLLVQSITFFLFNDAFRNSITVLFEDGKWSPPIVPGLHSRVEFTIPVNDLIHGSCTENPHLLVRHSIYVSIHSREPSSLSRKLAPPFLRTHKAKSNSLFSMKRPSSSSSSLSGSWHGDTENSVKQSLASPSEASLPNLSKYSRKNAKKLNEWLDSLDFKLPIYLFHRKLESELSHLPPYSPYRDSYFYLEDDDGDADTPSTASLDYFSNISPPDFLNKA
What are the official names of this protein?
Uncharacterized protein C895.08c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDHK_TRIV2
Sequence: MVLNSDLTTQDKERIINPIERPTVTQDLSENVILTTVDDLYNWARLSSLWPLLFGTACCFIEFAALIGSRFDFDRFGLIPRSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEAIIDAIIKLRKKIANDSMQERSLIRQTHRFYSTTHNLKPVAEILTGKYMQSETRFNPPKELTEAIGLPVPPALLTSQTQKEEQKRG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MIAB_CLOBL
Sequence: MNEILNTKDINTIGEFFIETWGCQMNEEDSEKLSGMLKKEGYIRTEERENADVIIFNTCCVRENAELKVYGNLGILKGLKSKNPNLIIAVTGCMMQQKGMAETIKKKFPFVDIIIGTHNLHNFPNYLNEVKKKDTSVLKIQEKEDSIIENMPIDRKNSMKAFVTIMYGCNNFCTYCIVPYVRGRERSRTPENIEAEIKKLISEGYKEITLLGQNVNSYGKDLEPNVTFAELLKRVNNIEGLERVRFMTSHPKDLTDDVIEAIAKCDKLCEQIHLPVQSGSSEILKKMNRHYDREKYLDVVSKIKKLIPNVALSTDIIVGFPGETEKDFEETLSLVKEVEYDSAFTFLYSIRKGTPAAKFEDQVPEDVKHKRFNRLVEVVNEISAKKNKAYEGKIEEVLVEGTSKNDENKLMGRTRTGKLVNFIGDKDSIGEFVNVKIIKANSFSLTGEEI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_DESPS
Sequence: MRYSQSFIPTKKETPAEAEVASHQLMLRAGFMRKLSSGVYSYLPYGLAAIRKVENIVREEMNRAGAQEMLMPMVQPADLWKETGRYEKYGPELLRFFDRNNRESCLGPTHEEVITDIVRNELSSYRDLPINLYQIQTKFRDEIRPRFGLMRGREFVMKDAYSFDVDDEQANLSYDKMFEAYKRIFTRCGLQFRPVQADSGAIGGSHSHEFMVLAKTGEDTIVVCKDCEYAANMEKAEVKLVATENDEALAELEKIETPGKRKVNAVCDFLQITPQQLVKTMVFEADGEAVAVLVRGDREVEEVKLKNLLGVADVELMDDKAVFDATGVPTGYLGPVAIPIRVVADQEVMVMKNFYVGGNEKNFHLKNVNIERDCTVSAVADLRQISTDDPCPRCGGRLELTEGIEVGHVFKLGTGYSESMNARFQDGTGDEKPFVMGCYGIGVSRVVAAAIEQNHDKDGIIFPVPLAPYTVTVLNLGLKDPEITAAAEKLYAELQAAGLSVLLDDRDERPGAKFKDADLLGIPYRLTVGKGLAKNGMVEVRRRRDGHTEEMTPEVAADFLARCIQAELTD
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_LACCB
Sequence: MSIKTEEISSLIKKQLEGYQDDLAAEEVGTVTYIGDGIARATGLENAMANELLQFSNGSYGMALNLETNDVGIIILGDFDEIREGDQVKRTGRIMEVPVGDAMIGRVVNSLGQPVDGLGAIKTDKTRPIEFKAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRKTGKTSIAIDTILNQKDQNMICVYVAIGQKDSTVRAQVETLKKYGAMDYTIVLTAGPSEPAPMLYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQATSYRELSLLLRRPPGREAYPGDIFYTHSRLLERAAKLSDKLGGGSMTALPVIETQAGDISAYIPTNVISITDGQIFLQSDLFYAGTRPAIDAGASVSRVGGDAQVKAMKKVAGTLRLDLASFRELEAFTQFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVIILYALTHGFLDPIPIEDITRFQDELFDFFDSNAADLLKQIRDTGNLPDTDKLDAQIKAFAGGFQTSKQLAAAKD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: F26_LITCT
Sequence: MADRLRELTQTRLQKIWIPHQCDRLQQRRGSSIPQFTNSPTMIVMVGLPARGKTYISKKLTRYLNWIGTPTKVFNVGQYRRDATQSYNNYQFFRADNQEAMKIRKQCALHALKDVHTYLSREEGHVAVFDATNTTRERRSVILQFAKERGYKVFFIESICDDPDIIAENITQVKLSSPDYTGCDREKVLEDFLKRIDCYQMNYEPLHDDLDSSLSYIKIFNVGSRYLVNRVQDHIQSRAVYYLMNIHVTPRSIYLSRHGESELNLLGRIGGDSGLSVRGKQYAHELGNFIKSQQIPDLKVWTSHMKRTIQTAEALHVPYEQWKALNEIDAGVCEEMTYEEIQDHFPEEFALRDQDKYRYRYPKGESYEDIVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKTAEELPYLKCPLHTVLKLTPVAYGCKVESIYLNIEAVNTHREKPLNVEVSRDPEEALDTVPEHF
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6PF-2-K/Fru-2,6-P2ase, PFK/FBPase, 6PF-2-K/Fru-2,6-P2ase liver/muscle isozymes.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: SEC23_LODEL
Sequence: MNFEEAEDINGVRFAWNAFPSTKAEAGKIVVPTGALYTPLKQREDLPIAAYDPVYCSNQSCKSILNPYCAVDPNGFWRCPLCQGRNSLPAHYHGINAENLPLELQNTSSTVEYITARPVQNPPIFTFVIDLCQDEENLKALIEDVIVSFNYLPPNALVGLITYGTMVQVHDLGSEKINKSYIFRGDKEYTDKQISDMLNRPVAPVLNQQQQQQQQQQPLQQQQQLANSLTRFFLPLEDVEFQLTSLLEGLNRDPWAVANGARPLRSTGSALNVAISLLGLTFPGFGARVMLFAAGPGTLNPGLIVGNQLKEPIRSHSDIDKDNAKHFKKAAKFYDALAAKAVKNCHTVDIFAGCYDQIGLLEMKNLCNNTGGTMLLSDAFTTSIFKRSFLRLFNKDEEGYLLMGFNGTFEIRTSKELKVSGLIGNASSLGVKTSNVSENELGIGGSSHYRLCSTSPRHTYAVFFDVANTQQLPPTAQSYIQFITHYQHSSGTYRIRVTTVSNYLTSDEQSLTNSFDQEAAAVIMARVTIFKSEQDDGADVLRWVDRMLIRLCQKFADYRKDQEESFRLGPQFQLYPQFIYYLRRSQFLQVFNNSPDETAFYRHVLLTEDANNSLIMIQPTLTSFTLDGEPEAVLLDSVSIKDDRILLLDTFFHILIFHGKTISAWRKAKYQEQEEYANFKQLLDEPKQEAAELLADRYPLPRFIDTEEGGSQARFLYSKLNPSVTYNTNEMIGGPGMGGAGGAIVLTDDVSLQVFMSHLQKLVVSGSS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDSA2_PSEPK
Sequence: MIKINSTIECSNSAPFVLFGGINVLESEDLALTACAEYVRVTQKLGIPYVFKASFDKANRSSIHSYRGPGMEEGLRIFEKVKAEFGVPIITDVHEIYQTAPVAEVVDVLQLPAFLARQTDLVVALAKTGKPVNIKKPQFLSPSQMQNIVHKFKEAGNDQLILCDRGTCMGYDNLIVDMLGFGVMKRTCQDLPIIFDVTHALQNRDPSGAASGGRREQVVELARAGMGVGLAGLFLEAHPNPDQAKCDGPSALPLDKLEPFLAQIKALDDLVKSFPQLTIA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase 2, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase 2, KDO-8-phosphate synthase 2, KDO 8-P synthase 2, KDOPS 2, Phospho-2-dehydro-3-deoxyoctonate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_COCIM
Sequence: MASALAGPRFPPLPKTLLIISLKMYFTPSRTIDYIQGLLEPRNDIIRQENRSRLLLALIPDFLTIYPCSEAIKEFESNLAAPQDADTPPPLLLGAQDCFWDSLGPYTGEISPVCLRDMNVSIVELGHAERRAIFGETDQQVARKAAAAADQGLIPLVCIGEVSTLGPIVSEAIGRAVGECEAQIRPVLEALPRDAPVIFAYEPVWAIGKPQPARVDHVGAVVSGIRSVIERIDRHRKGEVRILYGGSAGPGLWGPGGLGKEVDGMFLGRFAHDIEGVRKVVREVEESLR
What are the official names of this protein?
Putative triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_SYNR3
Sequence: MPPSFFKKRLSPIKPGDPIDYKDTDLLKKFITERGKLLPRRMTGLTARQQRDLTNSVKRARIVALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: IPK_ARATH
Sequence: MELNISESRSRSIRCIVKLGGAAITCKNELEKIHDENLEVVACQLRQAMLEGSAPSKVIGMDWSKRPGSSEISCDVDDIGDQKSSEFSKFVVVHGAGSFGHFQASRSGVHKGGLEKPIVKAGFVATRISVTNLNLEIVRALAREGIPTIGMSPFSCGWSTSKRDVASADLATVAKTIDSGFVPVLHGDAVLDNILGCTILSGDVIIRHLADHLKPEYVVFLTDVLGVYDRPPSPSEPDAVLLKEIAVGEDGSWKVVNPLLEHTDKKVDYSVAAHDTTGGMETKISEAAMIAKLGVDVYIVKAATTHSQRALNGDLRDSVPEDWLGTIIRFSK
What is the function of this protein?
Catalyzes the formation of isopentenyl diphosphate (IPP), the universal five-carbon isoprenoid building block of all natural isoprenoids (PubMed:24327557, PubMed:26216978).  Acts in parallel with the mevalonate (MVA) pathway and plays an important role in regulating the formation of both MVA and methylerythritol phosphate (MEP) pathway-derived terpenoid compounds by controlling the ratio of isopentenyl phosphate (IP) and dimethylallyl phosphate (DMAP) to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Controls the levels of IP and DMAP that are competitive inhibitors of the farnesyl diphosphate synthase.  Regulates the production of farnesyl diphosphate-derived terpenoids in the cytosol, and geranyl diphosphate-derived compounds in plastids (PubMed:26216978).
What are the official names of this protein?
Isopentenyl phosphate kinase, AtIPK, IPK.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl phosphate kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PACS2_MOUSE
Sequence: MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLAVLRELEKELLSVVIAVKMQYPHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSINMAEVMQHPSEGGQVLSLCSSIKEASVKVAEIWIVSLSSQPIDHEDSAMQAGPKTKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSEEVLDSEQDPAEHVPEVEEDLDLLYDTLDVENPSDSGPDMDDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHREPPSPADVPEKTRSLGGKQQLSDSVSDTVALSAAVPREPSGQPEDSPEAETSTLDVFTEKLPPSGRIIKTESLVIPSTRSESKPAGRRGRSTSLKERQPARPQNERANSLDNERCPDTRSQLQIPRKTVYDQLNHILISDDQLPENIILVNTSDWQGQFLSDVLQKHTLPVVCTCSAADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLIIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQSSVQDTPDIVSRITQYISGANCAHQLPIAEAMLTYKQKSPDEESSQRFIPFVGVVKVGIVEPSSATSGDSDDAAPSSSSILSSTPPSASTSPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDMPTTKNTLKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKTKDKEVESKSQCIEGISRLICTAKHQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF
What is the function of this protein?
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis.  In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.  May also involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments (By similarity).
What are the official names of this protein?
Phosphofurin acidic cluster sorting protein 2, PACS-2, PACS1-like protein.
What is the protein family that this protein belongs to?
Belongs to the PACS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Mitochondrion.
Protein: GPDA_ECOLC
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAYRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_SYNPW
Sequence: MSLTLERGAIAPLPVLQDNIIWIWSCGSEAVVVDPAVAEPVIEALQQKGLTLIAVLQTHHHADHIGGTPDLLRQWPDAAVIASGQDRGRIPFQTQPVAAGTRFTLLGVPVDVIDVRAHTSAHLAFFLPEGCSPGGHPPALFCGDTLFSGGCGRLFEGTPDDMHRALQTLATLPESTRIYCAHEYTEGNLRWAHALQPEDRAIKARLEDVIALRTQHKLTIPSTLAEEHRSNLFLRAQSAAELGRLRQLKDDWKGF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.