PharMolix/UniProtQA huggingface dataset:
Protein: HAP1_YEAS7
Sequence: MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNIPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQNRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHMNQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQESSDELKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITSQMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMNGAGTANTDTSANGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGLVDFYRADFPIWE
What is the function of this protein?
Regulation of oxygen dependent gene expression.  It modulates the expression of Iso-1 (CYP1) and Iso-2 (CYP3) cytochrome c.  In response to heme, promotes transcription of genes encoding functions required for respiration, controlling oxidative damage and repression of anaerobic genes.  Binds to the sequence 5'-CGGNNNTNNCGG-3' (By similarity).
What are the official names of this protein?
Heme-responsive zinc finger transcription factor HAP1, CYP1 activatory protein, Heme activator protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ2_MYCLE
Sequence: MARDYYGLLGVSRNASDADIKRAYRKLARELHPDINPDEAAQAKFKEISMAYEVLSDPEKRRIVDLGGDPMENAAASPSGFGGFGGLGDVFEAFFGGSSASRGPIGRVRPGSDSLLPMWLDLEECATGVTKQVTVDTAVLCDRCQGKGTNGDSAPIPCDTCGGRGEVQTVQRSLLGQMVTARPCPTCRGVGVVIPDPCCQCVGDGRVRARREITVKIPSGVGDGMRVRLAAQGEVGPGGGPAGDLYVEVHEQAHDIFVRDGDDLHCTVSVPMVDAALGTTITVDAILDGMSEIDISPGTQPGSVIELRGQGMPHLRSNTRGNLHVHVEVMVPTRLDQHDTELLRELKRRRSRDVAEVRSTHAAGGGLFSRLRETFTNR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHXP_ECO57
Sequence: MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANGVGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI
What is the function of this protein?
High-affinity transporter for guanine and hypoxanthine.
What are the official names of this protein?
Guanine/hypoxanthine permease GhxP.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEA_DEHM1
Sequence: MKTSDFDYNLPQEYIAQKPAEPRDSSRLLVLNRQSGELKSCIFRDITGYFQPGDVLVMNNSRVLPARIKGIKQDTSAKIEILLLKSDGNGCWEALLKPGKRTKPGTIIDIRKQDGQIHIQAEVLADKEDGIKLLRFSDETLLMKLGEVPLPPYIHTPVSDPERYQTVYALTNGSVAAPTAGLHFTPELLERLGDMGVICTYVTLHIGLDTFRPVKEEDPSDHIIHREYGILSAETAAAICQAKANGKRVFCVGTSATRLVEQASSLSQNGIIELYSGWADLFILPGYKFKVADCFITNFHLPRSTPLMLTAAFAGWPLLQKAYEKAINEHYRFYSFGDAMLVL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMJ_ECOLI
Sequence: MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKPWEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSFHACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLGFEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR
What is the function of this protein?
Acetylates the N-terminal alanine of ribosomal protein S5 (PubMed:385889, PubMed:2828880).  Also plays a role in maturation of the 30S ribosomal subunit (PubMed:18466225, PubMed:20176963).  Plays a role in the temperature regulation of pap pilin transcription (PubMed:1356970).
What are the official names of this protein?
[Ribosomal protein S5]-alanine N-acetyltransferase, Acetylating enzyme for N-terminal of ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. RimJ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP2_CHICK
Sequence: MSALTKASGSLKSVDYEVFGRVQGVCFRMYTEEEARKLGVVGWVKNTSQGTVTGQVQGPEDKVNAMKSWLSKVGSPSSRIDRTKFSNEKEISKLDFSGFSTRY
What is the function of this protein?
Its physiological role is not yet clear.
What are the official names of this protein?
Acylphosphatase-2, Acylphosphatase isozyme CH1, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RUVB_CAMC1
Sequence: MDRIVEIEKVSFENDFEVSLRPSKFEDYIGQEKIKQNLDVFIKAAKKRNECLDHVLFYGPPGLGKTTLAHIIANEMGVSIKMTAAPMIEKSGDLAAILTNLQEGDVLFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPKFTLIGATTRAGMISAPLRDRFGMDFRLQFYTSSELSRIVQIASAKLGKECDKNASLEIAKRSRATPRIALRLLKRIRDFAEVNDEQIISHERAKEGLNALGVNSLGFDEMDIRYLEILMQARRRPMGLSTIAAALSEDEGTVEDVIEPYLLANGFIERTAKGRIASAKCFETFNVKIDIEKGLFE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PAFA_MYCGI
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLIQLVTHDRAGERVLEDLLIDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATFCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSESTTMLKVGSASLVLEMIEAGVAFRDFSLDNPIRAIREVSHDLTGRRPVRLAGGRQASALDIQREYYARAVEYLQSREPNTQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYNMELSDPKISQLDLAYHDIKRGRGVFDLLQRKGLAARITTDEEIEAAVNTPPQTTRAKLRGEFISAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVKRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: MDTH_SALDC
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAILFILCALFNAWLLPAWKLSTVRTPVREGMRRVMSDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKRTPRRMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFA1_HUMAN
Sequence: MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLKSAEAVGVKIGNPVPYNEGLGQPQVAPPAPAASPAASSRPQPQNGSSGMGSTVSKAYGASKTFGKAAGPSLSHTSGGTQSKVVPIASLTPYQSKWTICARVTNKSQIRTWSNSRGEGKLFSLELVDESGEIRATAFNEQVDKFFPLIEVNKVYYFSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLPTVQFDFTGIDDLENKSKDSLVDIIGICKSYEDATKITVRSNNREVAKRNIYLMDTSGKVVTATLWGEDADKFDGSRQPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEAYKLRGWFDAEGQALDGVSISDLKSGGVGGSNTNWKTLYEVKSENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNKKVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQENQWVTCFQESAEAILGQNAAYLGELKDKNEQAFEEVFQNANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYREYGRRLVMSIRRSALM
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism (PubMed:27723720, PubMed:27723717).  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (PubMed:9430682).  In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.  Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response (PubMed:24332808).  It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage (PubMed:17765923).  Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair (PubMed:7697716).  Also plays a role in base excision repair (BER) probably through interaction with UNG (PubMed:9765279).  Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage.  Plays a role in telomere maintenance (PubMed:17959650, PubMed:34767620).  As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair.  Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase.  The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA synthesis by polymerase delta in presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange (PubMed:19996105).
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Enriched in PML bodies in cells displaying alternative lengthening of their telomeres.
Protein: CH60_TETHA
Sequence: MAKDIKFSEDARRSMLNGVSKLADTVKVTLGPRGRNVVLEKSYGSPLITNDGVTIAKEIELENRFENMGAQLVSEVASKTNDIAGDGTTTATVLAQSIVSEGLKNVTSGANPLGIRRGIEQATQKAVEELQNISTPVESKEAIVQVGEVSSGSKQVGQYIADAMDKVGNDGVITIEDSQGIDTELDVVEGMQFDRGYLSQYMVTDNEKMEADLDSPYILITDKKISNIQDILPLLEQVVQESKPLLIIADDIDGEALPTLVLNKIRGTFNVVATKAPGFGDRRKAMLEDIAVLTGATVITEDLGLELKDATMDSLGKANKVTVDKDNTTIVEGAGDSTAIEDRVQLIKNQVAETTSDFDREKLQERLAKLAGGVAVIKVGAATETEQKELKLRIEDALNAARAGVEEGMVSGGGTALVNVINKVAELDADDDAITGVNIVLRALEEPVRQISENAGFEGSVIIEKLKSEKLGIGFNAATGQWVNMVDAGIVDPTKVVRSALQNAASISALLLSTEAVIADRPDESGNDAGAGAQGMDPSMMGGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_STRCO
Sequence: MPDTAPTAARARLADARLYLCTDARRSQGDLPEFLDAVLAGGVDIVQLRDKGMEAAEELEHLAVFADACARHGKLLAVNDRADVAHAARADVLHLGQGDLPVPAARAILGDDVLIGRSTHAESEAAAAAAQEGVDYFCTGPCWPTPTKPGRHAPGLDLVRRTAALGTDRPWFAIGGIDLGNLDEVLEAGARRVVVVRAITAAEDPGAAAAEFARRLRQAPAHG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: Y4775_DICDI
Sequence: MSEPELKVSVSQLAPSDREGWLTKQGGSIRTWRRRWFVLKGKKLFYFKSKGDIEATGLIELEQNSFVKEEKDKDKKKKYMFTVGTSKRVFYIFAETETDMKQWMESIKRNLDGEGGMKSGGNDIVSSPKINSEPTPKVNQNGSAPEKSSLSSPRSKISNAKSIIPFLREEESKVLEFWQIWSESIPPQSDLQSGTAIEFHVATSIDMQKLTWRTAGPQNIFIQKMVDFFWNVGAPESEIDRLNDVGAIINPVKIGSWIDMSDKGGMDGGWYFPVDIPLKLAIEASDAGEPTRKLSEWAESNEVVNCYSIGRDMGAAPPRQTETRFKLPGPDFIAQLNLAVDAFKTFEFPPIPSNALEILYQSSNTLEAGGLCLSVITSSEGFVRLGLLIPKPTRDVVGQLCEIGQANRERISKFETALGGCGPAFVEFQYLQKGFGYTVYKEGFDIVFHYMVGEDQSE
What are the official names of this protein?
PH domain-containing protein DDB_G0274775.
Protein: GHRB_SALNS
Sequence: MKPSIILYKTLPDDLLHRLEAHFTVTQVPNLHPETVARHAQAFASAQGLLGASETVNRALLEKMPALRAASTISVGYDNVEVDALTARKIVLMHTPAVLTETVADTVMALMLATARRVVDVAERVKAGEWTESIGPAWFGVDVHHKTLGIVGMGRIGMALAQRAHFGFTMPVLYHARRRHQEAEDRFNARYCDLDTLLQEADFVCVILPLTAETRHLFGATQFARMKSSAIFINAGRGPVVDENALIAALQNGEIYAAGLDVFEQEPLSVDSPLLNMSNVVAVPHIGSATHETRYNMMACAVDNLIDALQGKIEKNCVNPQAAG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBZ_VITVI
Sequence: MTIAFQLAVFALIATSSILLISVPVVFASPDGWSSNKNIVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: MDT28_CAEEL
Sequence: MFEELDAEDGGEEQEMPMNVPEFGGGGEDIDDILGDAPDLPDDEYSNSVPQGAADGSIENDERRMRNDGAGSTNEDDEEPIEPTYLGDAIDSLMMHWCQLLTNVSVKAPVPPPSTLNHVKEVAEVCSKHFRDASVDVNNEFTRLGVQWEMEQPYSQYAIEEENLDEAIERQETIIAAAREMLNSRIQIYNEAHPNAGKHFTT
What is the function of this protein?
Plays a role in normal growth and development.
What are the official names of this protein?
Coiled-coil domain-containing protein mdt-28.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly localizes to the nucleus.
Protein: ARLY_YERPP
Sequence: MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_ACIAD
Sequence: MFFAVITLFPEMFEAITAYGISGRATKRQIATVSCINPRDFAEGNYKRVDERPFGGGPGMVMMAEPLAKAIIHAKQLAEQAGCVHAPVVYMSPQGKTLNEHAVQQFVDYDGLIVLCGRYEGVDERLIQHYVDQEWSIGDYVLSGGELPAMVLLDSIIRRLPDAMSDEQSHIQDSFVDGLLDCPQYTKPDHFEGLDVPEVLKSGHHANIEKWRFLQRYQRTLDRRPELVEKVTLTKQQRKWLTFLDDSKN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_BACCR
Sequence: MQQTKKLTQSDIIIAVMSGPFLQRGEPALISKWYRTKMALANGVDLVVELPYVFATQKAETFANGAISILNALRVSEICFGSEDGQIENFYNTISIQKNEEETFNCLVKQFMDAGNSYAKATSDAFSHILTSEKNIDMSQPNNILGFQYMKAILSQNSSIQAQTIKRFASHYHDETFNDQHIASATSIRKQLFSEEGSFTTIEPFLPQATTSLLANYKQNYGILHNWEQYFSFFKYRLMTMSPGDLRHIYEIEEGLEHRILSKIQNSSSFYSFMEALKTKRYTWTRLQRACTHILTNTTKEDIRSANIEQHAPYIRLLGMSQKGQTYLSKNKKKIELPILTHTKTFDHVALDIEKKANSVYFSIMHEPLRTQLLKQDITHHPIRYDETTTKFL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_CHLPN
Sequence: MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTGSINWFVHAFITGPKALTWISPSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYLSLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAGCGWWLAIVILATIKEKLAYSDIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSSKHQPSISKARTQRRSL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NXNL1_XENLA
Sequence: MADLFLDKILVKNNRDQDELDTEREIWERLENRVILLFFAKSRSSQCQEFAPLLKDFFVRLTDEFYVDRSSQLALVYVSLDQSEEEQERFLKDMPKRWLFVPFKDEEFRRNLEAQFSVSRVPVLVVLKPSGHVISFNAVDEVVRLGPPCFKNWQEVSEIIDRSFLLPEFTDDRAGRSMTDPIRRIKYKDETTNEKKKRKHCDDEDEGGGGGTEFF
What is the function of this protein?
Plays an important role in retinal cone photoreceptor survival (By similarity).  May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods (By similarity).
What are the official names of this protein?
Nucleoredoxin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment.
Protein: MOAC_CAMJE
Sequence: MKLSHLDEKNHPKMVDVSDKNITLRIATASGIIYMSQEAFDVIKNNTAKKGPVLQTAIVAAIMGVKKTSEIIPMCHPLMLSKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CAPSD_CFMVN
Sequence: MMVRKGAATKAPQQPKPKAQQQPGGRRRRRGRSMEPVSRPLNPPAAVGSTLKAGRGRTAGVSDWFDTGMITSYLGGFQRTAGTTDSQVFIVSPAALDRVGTIAKAYALWRPKHWEIVYLPRCSTQTDGSIEMGFLLDYADSVPTNTRTMASSTSFTTSNVWGGGDGSSLLHTSVKSMGNAVTSALPCDEFSNKWFKLSWSTPEESENAHLTDTYVPARFVVRSDFPVVTADQPGHLWLRSRILLKGSVSPSTNL
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 180 capsid proteins.  Each icosahedral unit contains three protein subunits (Potential).
What are the official names of this protein?
Capsid protein, CP, Coat protein, Protein P4.
What is the protein family that this protein belongs to?
Belongs to the icosahedral plant coat protein family.
What are the subcellular locations of this protein?
Virion.