PharMolix/UniProtQA huggingface dataset:
Protein: PSTB2_STRPB
Sequence: MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFEKHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKHLGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKSAFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIVTHNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNAK_METBU
Sequence: MGKILGIDLGTTNSCMAVIEGGKPTVIPNAEGGRTTPSVVGFSKKGDKLVGQVAKRQMIANPGNSVSSIKRHIGEGDYKVNLSGKDYTPQEVSAMILRKLKDDAEAYLGETITQTVITVPAYFNDSQRQATKDAGQIAGLEVLRIINEPTAASLAYGLDKEEGDHKILVYDLGGGTFDVSILELGDGVFEVLSTSGNTHLGGDDFDQRITEFLVEEFKKAEGIDLSNDKAALQRLNDAAEKAKIELSGVASTNVNLPFITADSNGQPKHIDIDITRAQFEKMTEDLVAKTLESMKMALSDAKLTTKDIDRVLLIGGSTRTPAVYNLVKNFIGKDPYKNINPDEAVAVGAAIQAGVLSGEVHDVLLLDVTPLTMGIETLGGVATPLIERNTTIPVKKSQIFSTAADSQPSVEIHILQGERGIASANKTLGRFVLDGIPPAPRGLPQIEVTFDIDSNGILHVNAKDLGTGKEQSISIQKPGGLSDEEIERMVKDAELHAEEDKARKEEVETRNNADSLVNAAENTLKEAGDVATNEQKEQIEAAIADLKTALEGEDLEAIKSKTEALQESVYKVSAAMYEKAQKEASAGAEASEDASGPSSTGSASDDDVVDADYEVVDEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RNPA_THEBO
Sequence: MDEKDLAAQPEEAGQDPRLPGPHEDPRRQEGAEAQAAEGPLAPHAQGERLKRPPPAPGGKLVSLKGDRAFQRLRKGKAGRGRYVSVKWLPAPELRVGIVVSKKVGKAVVRNKVKRRLREILRRLHLPKAHLLVVASPEAREASYVELFQDVARALKKSGLIQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: TTC22_HUMAN
Sequence: MAELEAVADDLDALIDDLDYLPGHFHLEMQLNFEPRSPAPQRARDLKLQREGLRQELQLAAAPQRPAVRHLLGAFAFYLEELDEARECFLEVAHEHPGNLNAWANLAHVYGRLGQEEEEEACAARLADLMGLAEEPEAAGDPQLRAARCLAEQGYAHGFDVGCASPEERARGLAAGIALYDKALGYGQQIPMEEKRGWYFTMATLYIRLDGIFLELGSEEQKRLPAFNRTLALLRQVLKSEDPRHRALAWCYLGMLLERKDTFSTTPMGVHDCGYSGTDPLDCFGKAIEIAKNQPPILNRLAKIFYFLGKQDMAIGTCNMALDVLRDPELNWQAYCTRAKIHIRAYLHDLKRAKMGLGGMPDRNHLACAKADLEEVVRVCPGFKAYLDIGQVYYYMGVDAVQELLAVDEAALNQALVFLAKAGESELGATLPELQLLRGKCLRIKGEDANAAACFKRAVELDDAGSSHTDGFGCLLEALLAQWSQAQLSDGELGREVDAWLRRAQDKYPAARLRQELQRVWRGHTDEVLGLARALVAQGRPALVRLLFETMEREGEGASAPRDRRAVSF
What are the official names of this protein?
Tetratricopeptide repeat protein 22, TPR repeat protein 22.
Protein: KITH_XANAC
Sequence: MAKLYFYYSAMNAGKTTTLLQSAHNYRERGMRTLILTPKLDHRAGSGVVASRIGLRADGRIFERDTELQQLVERDIHNDGALHCVLVDEAQFLSRAQVWQLSEVVDRLRIPVLCYGLRTDFRGELFEGSQFLLAWADELEEIKTICHSGSKATMTVRVDAHGHAVQDGPQVEIGGNERYVSVSRAEFKKIMRGEGRIDPLQIALPLPVA
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_ACHLI
Sequence: MIKLDIKDAKKFLKTNVFSLQDQVNELHDVIQNKSGLGNDFLGWLDLPLTYDKEELDRIYKLKEQHKNVDAIVVIGIGGSYLGAKAGYEFLKTPFKKQKPELIFAGHHLSANYLKHLLKYLNKKNYVINVISKSGTTTEPAVAFRLLKAHIENKYGVKEARKRIFATTDKARGSLYQLAINEGYERFVIEDNVGGRFSVLSAVGLLPFVFVGIDVEKMIKGAQDAYHDAQDPSLKKNKAYLYAVTRFLLNQSGKDVEYLINYEPRLAFFAEWWKQLFGESEGKGGKGLLVHSASFTTDLHSLGQQIQDGNRIIFETVLNVKKTDKLSIPFVEEDLDKLNYIAGKEISYVNEQAFLGTKEAHIDGGVPNIVITIDKMDAYHFGYLVYFFEIACAMSAYLLEVNPFDQPGVEAYKKNMFRLLGKK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_BACCN
Sequence: MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEVFHKELEQLQQQNARLKRELEEQKLAAAQAPQQTIPTPAAQPVYSNTNTDILKRLSNLEKAVFGSKLYE
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: NU4C_NICSY
Sequence: MNYFPWLTIIVVFPIFAGSLIFFLPHKGNRVIRWYTICICILELLLTTYAFCYHFQSDDPLIQLVEDYKWINFFDFHWRLGIDGLSIGPILLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYLLLCMWGGKKRLYSATKFILYTAGGSVFLLMGVLGLALYGSNEPTLNFETSVNQSYPVVLEIIFYIGFFIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHSIFSPWLMIIGTIQIIYAALTSLGQRNLKKRIAYSSVSHMGFIIIGISSLTDTGLNGALLQIISHGFIGAALFFLAGTTYDRIRLVYLDEMGGIAIPMPKMFTMFSSFSMASLALPGMSGFVAELIVFFGIITGQKYLLIPKILITFVMAIGMILTPIYSLSMSRQMFYGYKLFNAPKDSFFDSGPRELFLSISIFLPVIGIGIYPDFVLSLAVDKVEVILSNFFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ADEC_ECO81
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIDRQPVSASDFALQFTPGKRYRVIEVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: EFTU_CALS8
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLALKGKAQFMAYDQIDKAPEERERGITINTAHVEYETDARHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVNVPYIVVFLNKVDMVDDPELIELVEMEVRELLSKYGYPGDEVPIVKGSALKALESPSQDPNAPEYQCILELMDVVDKYIPTPQRDVDKPFLMPIEDVFSITGRGTVVTGRVERGTLKTGEEVEIVGFAPEPRKTVVTGIEMFRKVLDEAVAGDNVGCLLRGIQKNEVERGQVLAKPGTIKPHTKFKAQVYVLTKEEGGRHTPFFNGYRPQFYFRTTDVTGTITLPEGVEMCMPGDNVEMTVELISPIAIESGLRFAIREGGRTVGAGSVTTIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_BORHD
Sequence: MAKSDVKGINLGMGTGRRKSSVARVYIREGKGDIKINSRDFDSYMQLEKLKTIALSPLVLTNTLGKYDLYINIYGGGISGQAGAIRHGIARALFNLDEEHKMILKSNGFLTRDPRKVERKKFGKKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: URED2_PSESM
Sequence: MNLPAHTALFTPSWHAELELGYGRFYDCTRPTQRRHKGPLRVQKHLYAEGPEVCQHIIVHPPGGIAGGDRLDISVNVGAHAWAQLTSPGAAKWYRAASPAFQQLELHVQPGATLEWLPQETIVFSNAQAELTTRIELHGDARLCYWDVVALGRPASGERFEHGHFQSHLDIRRDGTLLWHERQRIIGADGLLDSPIGLDGKTVFATLLLTGDVDSDLLEVCRSLSMPSPVRGNLTQLPGLIVARCLADEALHARAWLIEIWKRLRPALLGREAVMPRIWNT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 2.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_STRPJ
Sequence: MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVYGAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MEMO1_MOUSE
Sequence: MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAAHAYKQVDPSVTRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRSWQDSSVSYAAGALTVH
What is the function of this protein?
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton.  Mediator of ERBB2 signaling.  The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.  It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.  In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity).
What are the official names of this protein?
Protein MEMO1, Mediator of ErbB2-driven cell motility 1, Memo-1.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: TRMB_BORBR
Sequence: MNTNTPAHPPEGAPLSEATQAALASAEHAPDSPGATHIRSFVHRRGHITQRQRDALEQLMGKWSVPYAPRPLDMAATFGRQAPTILEIGFGMGETTEKIALARPGDNFLGVEVFNAGVGSLLHRIEESAIANLRIVQHDAVEVVRDMIAPDSLAGVHVYFPDPWPKKRHHKRRLLQPPFVALLASRLAPGGYLHCATDWEDYAVQMLEVLGGEPLLRNTADGYAPRPDFRPQTKFETRGLRLGHGVWDLMFKRA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MIAA_CHLPN
Sequence: MLPFEFEFNTTSSPECDVCLDPQKLFVKLFKRTIVLLSGPTGSGKTDVSLALAPMIDGEIVSVDSMQVYQGMDIGTAKVSLKARQEIPHHLIDIRHVQEPFNVVDFYYEAIQACQNILSRNKVPILVGGSGFYFHAFLSGPPKGPAADPQIREQLEAIAEEHGVSALYEDLLLKDPEYAQTITKNDKNKIIRGLEIIQLTGKKVSDHEWDIVPKASREYCCRAWFLSPETEFLKNNIQMRCEAMLQEGLLEEVRGLLNQGIRENPSAFKAIGYREWIEFLDNGEKLEEYEETKRKFVSNSWHYTKKQKTWFKRYSIFRELPTLGLSSDAIAQKIAKDYLLYS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPB_CAMJR
Sequence: MKKAYYGDFGGQFLPESAMFALNELEGAFLKFSKDKLFKKELNELLKTYVGRPTPLYFARNLSKKYQHEIYLKREDLNHTGAHKINNAIAQALLAKKMGKKKIIAETGAGQHGLATATAAALLGLECEIYMGATDVQRQALNVYKMELLGAKIHAVQSGLKTLKEATTAAIQAWVGDIKNIFYVVGSAVGPYPYPKMVMHFQSIIGKECKMQLQKLNKKVDYIIAAVGGGSNAAGIFYDFIKDENVKLIGIEAGGLGIDTPYHAATLNKGKTGIIHGMKTKVLQDDLGNILPVHSVSAGLDYPGIGPLHAFLFESKRAQYHAISDEECMQALKLLCKEEGIIAAIESSHALAFLEKLCPTLKKKSVIVVNLSGRGDKDMQMIRDYKKGVIYG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PSEF_CAMJJ
Sequence: MKNLCIIPARGGSKRIPRKNIIDFLGKPLIAYSIENALNSGIFDEIVLSSDDEEIIEVALKYGAKAPFVRDKNLSDDYASSTAAVQNAIEILQSQNQIYDHVCCLYATAPLLNKNILKQAYEKFIQNQSKFLFAATEFEYPIQRAFYLNENNQVYMFDEKHYKSRSQDLTKAYHDAGAFYFGTSKAWLEEDFIFKPHSSVFVLPRNLVCDIDTMQDLEFAKILYKVNHESAF
What is the function of this protein?
Catalyzes the final step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Mediates the activation of pseudaminic acid with CMP by forming CMP-pseudaminic acid (By similarity).
What are the official names of this protein?
Pseudaminic acid cytidylyltransferase, Pseudaminic acid biosynthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the CMP-NeuNAc synthase family.
Protein: CXG1_CANLF
Sequence: MSWSFLTRLLEEIHNHSTFVGKIWLTVLIAFRIALTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQNQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEENLPADLETLQREIKMVQERLDLAIQAYSHQNNPHGPREKKAKVGSKAGSNKSSASSKSGDGKNSVWI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction gamma-1 protein, Connexin-45, Cx45, Gap junction alpha-7 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: PP1B_CHICK
Sequence: MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Involved in regulation of ionic conductances and long-term synaptic plasticity.
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TILS_STRZT
Sequence: MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB21_MYCTU
Sequence: MHRGYALVVCSPGVTRTMIDIDDDLLARAAKELGTTTKKDTVHAALRAALRASAARSLMNRMAENATGTQDEALVNAMWRDGHPENTA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in M. smegmatis neutralizes the effect of cognate toxin VapC21.
What are the official names of this protein?
Antitoxin VapB21.
Protein: NRDR_MYCA9
Sequence: MHCPFCRHPDSRVVDSREADEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSRDKVVKGVRRACQGRDVDDDALNLLAQQVEDAVRAAGSPEIPSNEVGLAILGPLRDLDEVAYLRFASVYRGFSSAEDFEREIAALRAHRDAPAES
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CCS1_TRIEI
Sequence: MDVEDSDKNSLINPLRIFKREILPLLADLRLAIALLLIIAICSISGTVIEQGESIAFYQENYPEKPALFGFLTWKVILLLELDHVYRTWWFLSILILFGASLTACTFTRQLPALKSANRWKFYNKKQQFKNLALSAEIETASLDSLEEILQKRGYKTSKEGDKLYGRKGIIGKVGPIIVHASMLIILAGSIIGSMTGFLGQEIVPSGETFQVKNIIDAGIFAKSQIPKNWSVRVNRFWIDYTPSGGIDQFYSDLSILDKSGEEVDRKTIFVNQPMRYHGVTMYQADWAIAAVKVRVNKSPVFRLPMAQLNTEGGGKIWGTWVPIKPDLSEGVSLLAKDLQGNVLVYDTSGKLVASVREGMFIEVSGVTLFIDKIIGSTGLQIKADPGIPIVYLGFGLLMLSVLMSYVSHSQIWAFQESERLYIGGKTNRANVTFEREILDILDRLGSDENISLEKQKQLFSDFSEGIKTSEN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ULAE_ECOLI
Sequence: MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDDRLSRLNWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMSSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: ALR_COPPD
Sequence: MWNKWAEVSRMNLKNNVELIRQKLPDLEPIAVVKDDAYGHDAAVVVPELLKNGITKFAVVYAKDALMLSEFGAEWILVLDDPPLSNMCSEYEKRGIRFCITDSKWLSDGLLELPIKFHLFVDVGMHREGVPWYETNTIREICKVVGNRLEGICSHLSNGLSDSQALATEEERFREVLSIAPEGLMVHLSNSASLYNAKFPYATHFRPGISLYGYGYPGLKPVLSLKARVIHEHILEPGEGLSYGWTWRATEPTHVVTVPVGYGDGYNRKLSNKAIAGSKAGNLQQIGTVTMDFTMFEAPKNVTVGDEIVLMGEWEGGHFWADEMAQLVGTIPYEVLTSINPRVPRVLV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ING1_MOUSE
Sequence: MLSPANGEQIHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDDYYEKFKRETDGTQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENRSRQVDSHVELFEAHQDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERAYNR
What is the function of this protein?
Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein.  Isoform 2 acts as a negative growth regulator by cooperating with p53 in transcriptional activation of p53-responsive genes and may act as a tumor suppressor.
What are the official names of this protein?
Inhibitor of growth protein 1.
What is the protein family that this protein belongs to?
Belongs to the ING family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIRD3_RHIRD
Sequence: MANGQFTIRSAGPASVGLTGERRGAASASSSALSNVQGDVRDRPIPTSSSRLPNAAILRDSSEIASTGLRYVAATLHWSEIAPLSLINKNDLAPAAYDFETRNDAGNVTAKVGRAVPVPKQGRLGKMLASVPLSTRISRVNSDRRLPTDAENHPETRDPRKGRGSHGVTPALHEKIGTAFVRRLRKIRTVLFAVAARLGAR
What are the official names of this protein?
Protein VirD3.
Protein: MDH_BACAN
Sequence: MTIKRKKVSVIGAGFTGATTAFLLAQKELADVVLVDIPQLENPTKGKALDMLEASPVQGFDANIIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVLTNPVDAMTYSVFKEAGFPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGGHGDDMVPLVRYSYAGGIPLETLIPKERLEAIVERTRKGGGEIVGLLGNGSAYYAPAASLVEMTEAILKDQRRVLPAIAYLEGEYGYSDLYLGVPVILGGNGIEKIIELELLADEKEALDRSVESVRNVMKVLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: GL813_ORYSJ
Sequence: MSSTPLLPVLLSTMILLSAVSTTTTALTQDFCVANLPLGADTPSGYQCRPAATVTAADFYSGALARPGILIRPFNTSLASAFVQQYPAVNGLGISASRVDILPGGVVPLHTHPAGSELLYVLDGALVAGFISSSDNKVYYKEVSKGGMFVFPQGLLHFQYNTGDTTAVAFAAYSSSNPGLQILDYALFANNLPTSYVVKGTFLAEAEVRRLKSKFGGSG
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 8-13.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CUTR_STRCO
Sequence: MRVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERIGVNDYDVVVLDRDLPLVHGDDVCRKIVELGMPTRVLMLTASGDVSDRVEGLEIGADDYLPKPFAFSELIARVRALGRRTSVPLPPVLERAGIKLDPNRREVFRDGKEVQLAPKEFAVLEVLMRSEGAVVSAEQLLEKAWDENTDPFTNVVRVTVMTLRRKLGEPPVIVTVPGSGYRI
What is the function of this protein?
Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism.  CutR suppresses a defective melC1 gene, encoding a putative copper-transfer gene, probably by altering copper metabolism (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein CutR, Defective melC1 suppressor protein.
Protein: PTH_BORT9
Sequence: MDLLIVGLGNPGSNFFHTRHNVGFGLIDKLVVKHGLSLKKVKNYEYSDFNFENKRIVLIKPLTYMNLSGNIFPSVFARFYMKMTNLLIVVDNVDLPLGKCKLRKVGGTSTHNGLRSISGSLGSTKYSRLYIGVGNNNESSLRDFVLAKFSDSELKRIKNVFNFLSEEILSIDECNFENKIATINSSSF
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.