PharMolix/UniProtQA huggingface dataset:
Protein: ACSA_THIDA
Sequence: MAAIESVLTETRVFPPAEAFVTQANVAGMEAYQALCRRAEADYEGFWAELARQHIDWKTPFTRTLDESDAPFYRWFDDGELNVSYNCLDRHLATRGDKTALIFEADDGSVRTVTYKELHARVCQFANGLKSLGVGKGDRVIVYMPMSIEAVVAMQACARIGAIHSVVFGGFSAKSLFERIEDAQAKLIVTADESLRGGKAVPLKRAADEALAMGDTSCVERVVVYRRSGGEVNWSARDLWWHELTQTQAETCEPVWVSAEHPLFILYTSGSTGKPKGVQHSTGGYLLGALLSMLWVFDAKADNDVYWCTADVGWITGHTYVAYGPLALGMTEVIFEGIPTYPHAGRFWETIAKHKVTTFYTAPTAIRSLIKLGSELPAQYDLSSLRLLGTVGEPINPEAWMWYHEVIGGGRCPIVDTWWQTETGAHMIAPLPGAVPTKPGSCTLPLPGIMAAVTDEHGGPVAKGQGGYLVIKRPFPSQLRTLWGDPERFKKTYFPEEMGGKTYLAGDSAHRDDDGYFWIMGRIDDVLNVSGHRLGTMEIESALVSNPRVAEAAVVGRPHEVKGEAVVAYVVLKGARAVGDEAKDIARELRDWVGKEIGPIAKPDEIRFGENLPKTRSGKIMRRLLRAIAKGEEITQDVSTLENPAILDQLKEAVK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: FLGI_SALHS
Sequence: MFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDARTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: MURB_LIMF3
Sequence: MQMENLITTFPEIEIKEHEPLAHYTNTKTGGPADWLAFPVDVAQVQQLVDYCHQTGLALTVIGNASNLIVRDGGIEGLVMILTRMQTVKVEGTMVTAAAGASYIEVTKIARDHSLTGLEFAAGIPGSIGGAIFMNAGAYGGETKTVVDHVTVMERDGQIHQLSNEEMDFGYRHSAVQASGAIVLDATFALKLGDQNAITAQMEDLNARRAAKQPLELPSCGSVFKRPTGYFAGKLIHDAGLQGYTSGGAQVSTKHAGFIVNVNHGTATDYLNVIHHVQETVQEKFGVQLETEVRIIGRQS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCB2_MOUSE
Sequence: EDLRNVTPPKVSLFEPSKAEIANKQKATLVCLARGFFPDHVELSWWVNGKEVHSGVSTDPQAYKESNYSYCLSSRLRVSATFWHNPRNHFRCQVQFHGLSEEDKWPEGSPKPVTQNISAEAWGRADCGITSASYHQGVLSATILYEILLGKATLYAVLVSGLVLMAMVKKKNS
What are the official names of this protein?
T-cell receptor beta-2 chain C region.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CBS_MOUSE
Sequence: MPSGTSQCEDGSAGGFQHLDMHSEKRQLEKGPSGDKDRVWIRPDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARELQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSVKRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFVAAREQTQT
What is the function of this protein?
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine.  This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity).  Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
What are the official names of this protein?
Cystathionine beta-synthase, Beta-thionase, Serine sulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPG_TERTT
Sequence: MASGKEIRTKIGSIKNTQKITSAMEMVAASKMRKAQDRMEVGKPYARRMREVVGHIAAGNLEYQHLYITEREVKRVGYIVVSTDRGLCGGLNVNLFKAVLRHSKEWADKGIETDFCMVGAKGTAFFKSVGANIVASLRDIGEQPSITSLIGSVKVMLDAFADGKIDRLYVCSNDFVNTMTQTPKVERLLPLKPEDGAIHKRSWDYLYEPDAKELLDGLMVRYIESQVFQAVVENGACEQAARMIAMKSATDNAGNLINELQLAYNKARQAAITQELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RDRP_TRVPS
Sequence: GAHLVPTKSGDADTYNANSDRTLCALLSELPLEKAVMVTYGGDDSLIAFPRGTQFVDPCPKLATKWNFECKIFKYDVPMFCGKFLLKTSSCYEFVPDPVKVLTKLGKKSIKDVQHLAEIYISLNDSNRALGNYMVVSKLSESVSDRYLYKGDSVHALCALWKHIKSFTALCTLLPRRKG
What is the function of this protein?
Replicase large subunit: is an RNA-dependent RNA polymerase active in viral RNA replication.
What are the official names of this protein?
Replicase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: SYY_BURP1
Sequence: MSTDPTSKPAFPITDEVRHALAVTKRGVDELLIEEEFAQKLAKSAATDKPLRIKLGLDPTAPDIHLGHTVVLNKMRQLQDLGHTVIFLIGDFTSLIGDPSGRNATRPPLTREQIESNAKTYFEQAALVLDRAKTEIRYNSEWSMPLGADGMIKLASRYTVARMLEREDFTKRFQGGIPISIHEFLYPLMQGYDSVALNADLELGGTDQKFNLLVGRELQKQYGQEQQCILTMPLLEGLDGVEKMSKSKGNYVGISEKPTDMFGKLMSISDVLMWRYFELLSFRSLDEIARFRGEAEGGRNPRDFKVMLAQEIVARFHSQADAERALEDFNHRAKGGVPDDIPAVTLAGAPLAIGQLLKQAGLVPSTSEALRNIEQGGVKIDGATVSDKALKVDAGEFVVQVGKRRFARVTLTA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ZYMMO
Sequence: MTDTAPKAPVVDIPAITALVEPEVKALGLELVRIAMFGGKSDPTLQIMAERPDTRQIGLTECEALSRRLSEIFDEQDPIEDAYRLEVSSPGIDRPLTRRKDYQDWKGFSARIRLSAPLDGRKQFDGEIIGIDDADNVILDCPKVGQKILPFSAIERSKLLLTDALIAATQPLDSEGADQIVREG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHS_METTH
Sequence: MIGKRIRIERIINRKTDRTVIVPLDHGVSIGPVRGIIDMAGTIDEVASGGANAVLMHKGMVRSGHRGYGRDIGLIIHLSASTGLGPDPNHKVLVTSVEKALKLGADAVSVHVNVGSEREPEMLIKLGTVAEICDDWGMPLIAMMYPRGKKIDDEHDPEVVKLAARAGAELGADIIKTNYTGDPDTFRDVVKGCPVPVVIAGGPKIETEEELLQMVSDSVEAGGAGVAIGRNIFQADSPANMTGAIAGIVHDGLSVEEAVRILKGGE
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: Y1098_BACAN
Sequence: MLYLHDVWVNWFEGEENGYNVCHFYEWRKDDTIELLDQVPLLKVDSTLYHYIENELLELPQKLLEDVHHKAYIRKNHERLQQEYCFVVTDGKGIIAIDTIGYNVPIRKSRLIPRQEQMVYEMVENVQAEKYEFQVEEMEKEHHILSPSPFVMNGLTRKERQLKQLLFMALDQLHTTKNTAEIRYWFTEWDPSAYGMVQHMEFEDIWAKLYDEAKTGWSEKHEQLCERLVKGQPFFEKLWEMENEQKVN
What are the official names of this protein?
UPF0736 protein BA_1187/GBAA_1187/BAS1098.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: DAPE_ECO7I
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMDFADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHAGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLVGEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MFDR_ARATH
Sequence: MSRYLARYMVSRYFSSASSRPLHVCIVGSGPAGFYTADKVLKAHEGAHVDIIDRLPTPFGLVRSGVAPDHPETKIAINQFSRVAQHERCSFIGNVKLGSDLSLSELRDLYHVVVLAYGAESDKDLGIPGESLSGIYSAREFVWWYNGHPDYSSLKPDLKTSDSAVILGQGNVALDVARILLRPTTELASTDIATHALSALKESSIRKVYLIGRRGPVQAALTAKELREVLGIKNLHIRIKQTDLSVTPADEEEMKTSRARKRIYELLSKAAAAAKTSEADPDQRELHFVFFRQPDQFLESDERKGHVSGVNLQKTILESVGTGKQIAVGTGEFEDLNCSMVLKAIGYKSVPVNGLPFDHKKGVVPNVKGRVVSHTSGDISQTEPGLYVCGWLKRGPVGIIATNLYCAEETVGSISEDIEEGVWKSSKAGSKGLMQLLEKRKVKKVEFSGWEKIDAKEKQMGIERNKPREKLVTWEDLLAAAAN
What is the function of this protein?
Associates in vitro with the adrenodoxin-like protein MFDX1 to form an efficient low potential electron transfer chain that is able to reduce cytochrome C (PubMed:12714594, PubMed:13677469).  Functions as accessory mitochondrial protein involved with BIO2 in the plant biotin synthase reaction (PubMed:12714594).
What are the official names of this protein?
NADPH:adrenodoxin oxidoreductase, mitochondrial, Adrenodoxin reductase, Mitochondrial ferredoxin reductase, AtMFDR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PGLRB_ASPNG
Sequence: MHFLQNAVVAATMGAALAAAAPLEKRSCTFTSASAAKSGKSSCSTITLDNIAVPAGETLDLTGLKKGTTVIFEGETTFGYKEWKGPLISMSGTDITVKQASGAKINCDGARWWDGKGSNGGKTKPKFFQAHKLDQSSITGLKVYNTPVQGFSILADHLTITDVTIDNSAGTSKGHNTDAFDIGQSTYITIDGATVYNQDDCLAINSGEHITFTNGYCDGGHGLSIGSIGGRSDNTVNDVTISNSKVLNSQNGVRIKTIYGKTGTVENVKFEDITLSDISKYGIVVEQDYENGSPTGTPTNGVKVEDITFKKVTGSVKSSGTDIYILCGSGSCSNWTWSGVDVTGGKKSSKCKNVPSGASCSD
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase B, Pectinase B, Polygalacturonase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU4M_XENLA
Sequence: MLKILLPTLMLIPSTWLTNKKWLWPSLTSQSLIISLLSLMWFFNQSETTHFSNYLMTIDQISTPLLILTCWLLPLMLIASQNHLSNEPISRQRTFITMLVFLQLSLIMAFSATELILFYIMFEITLIPTLIIITRWGNQAERLNAGTYFLFYTLAGSLPLLVALLSLYSSTGTLSLNLLQLLPNHIPMTWANYSWWLACLLAFMVKMPLYGTHLWLPKAHVEAPIAGSMVLAAILLKLGGYGIIRISITLSPSMKELAYPFLILSLWGIIMTSSICLRQTDLKSMIAYSSVSHMGLVISAGNNQTPMKALTGAMILNTSDGLTHSALCCLAKYQSYERTHSRALLLSRGLETILPLMGTWWLISNLANMALPPSPNWMGEITIMTALFNWSSWTIILTDLGTLLTASYSLYMFLMTQRGMTPEHLNAINPTHTREHTLMTMHLIPIIPLMMKPELIWGLFF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RPOC2_POPTR
Sequence: MAERANLFFHNKVIDGTAIKRIISRFIDHFGMAYTSHILDQVKTLGFHQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAIEKLRQSIEIWYATSEYLRQEMNPNFRMTEPFNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTTRGISVSSRNGMIPERIFIQTLIGRVLADNIYMGLRCIATRNQDIGIGLVNRFITFRTQPISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIKFNKGLVHPTRTRHGHPAFLCSMDLYVTIESQDIIHNVTIPPKSFLLVQNDQYVESEQVIAEIRSGTYTLNFTERVRKHIYSDSEGEMHWSTDVYHASEFTYSNVHLLPKTSHLWILSGGSCRSSIVPFSLHKDQDQINVHSLSVERGYISNPSVNNDKVKHKFFSSYLSSKSKKKSRILDYSDLNRMICTGFIYPTILHENSDLLAKRRKNRFIIPFQSIQEKELMSHSDILIEIPINGIFRRNSIFAYFDDPQYRRKSSGITKYVAIGVHSIVKKEDLVEYRGVKEFQPKYQMKVDRFFFIPEEVYILPESSSLMVRNNSIIGVDTQITLNTKSRVGGLIRIERKKKKMELKIFSGDIHFPRATDKISRYSGILIPPGTVKTNSKESKKVKNWIYVQRITPTKKKSFVLVRPVLIYERGDGINLERLFPPDLLQEKENLKLRIVNYILYGNGKPIQGISNTSIQLVRTCLVLNWNQDKKSSSIEEARVYFVEVSINGLIRDFLRIHLGKSRISYISRKRNDPSGLGLISDNGPDRTNINPFYSIYSKTRIPQSLKQNQGTISISTLLNRNMECQSLIILSSSNCFRMDPSNGVKSYNVIKESTKRDPIIPIRNLLGPLGTALQIANFYSFYHLLTHNQISVIKYLKLDNLKLKQTSKVLKYYLMDENGRIVNHDPYSNNVLNPFKLNWYFLHHNYHHNYCEETFTIINLGQFICENVCMTKNGPRLKSGQVLIVHADSVILRLAKPYLATPGATVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISINLEKRVENWNECITRIVGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNVFSPGELIGLLRAERAMRALEEAICYRTVFLGITRASLSTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGLAHRSSQHKIIPFKTKKKNLFEGEMRDILFHHRELFDSCISKNFYNISEQSFIGFNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MYP0_HETFR
Sequence: MFRDLKPAYLFCCSVLYAFSVLRPSQGISVSTHHNLHKTVGSDVTLYCGFWSNEYVSDLTTLSWRFRPDNSRDIISIFHYGNGVPYIEKWGQFRGRVEWVGDISKHDGSIVIRNLDYIDNGTFTCDVKNPPDVVGTSSDVHLTVYDKIPPVGAGVVSGAIIGTFLGIILLIVGGLYLFRYIVRRRARSETSFLQRRRSAAERGKVSGKAGTVSKGPVLYATLDQSKSGKGASEKKSKLSESKRDKK
What is the function of this protein?
Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.
What are the official names of this protein?
Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero.
What is the protein family that this protein belongs to?
Belongs to the myelin P0 protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GATA_XENLA
Sequence: MLGMSLREAAAVLRLGQVKPTELCQKCLSLIKETSFLNAYITITEDIALKQAAEADKRFAQGKPLGELDGIPIAIKDNFSTAGIETTCASRMLKGYVAPYNATVVQKLFDQGAVLMGKTNLDEFGMGSGSTDSIFGPVRNPWSYSRSYIEKRPISHHAAKDDSDWVIAGGSSGGSACAVSAGTCYLAIGSDTGGSTRNPASHCGVVGLKPTYGLVSRHGLIPLVNSMDIPGILTRCVDDAATVLGMLAGHDLYDSTTVQDPFQPFSLPETIDLSNLCIGIPKEYHAPGLSTEILSLWSKTADLLEKAGAKVMEVSLPHTPYSIVCYHVLCTAEVASNMARFDGLEYGHRSDIDDSTEAMYAATRREGFNDVVRGRILSGNYFLLKQNYEKYFVKAQKVRRLIADDFVKVFNSGVHVLLTPTTLGDAAPYLEFIQEDNRTRSAEEDVFTQCTNMAGLPAVTVPAGLSSRGLPLGLQFIGRAFCERQLLTVAKWCEKQMDFSPLQFNRDLGNGSIVLQYSKSASFV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A, Glutaminyl-tRNA synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: OGT_MYCBO
Sequence: MIHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDPGAFSGAVDQLNAYFAGELTEFDVELDLRGTDFQQRVWKALLTIPYGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTGYGGGINRKRALLELEKSRAPADLTLFD
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1439_MANSM
Sequence: MSLQVNSVAIMLVVLILLGVLSNNNSITISALILLLMHQTFLGKYIPFLEKNGLKVGIIILTVGVLAPLVSGKVQLPAFKEFLNWQMFLSIVIGIAVAWFAGRGVNLMSSEPIVVTGLLIGTVLGVAFLGGIPVGPLIAAGILAVILGK
What are the official names of this protein?
UPF0756 membrane protein MS1439.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_MYCGE
Sequence: MAKELIFGKDARTRLLQGINKIANAVKVTVGPKGQNVILERKFANPLITNDGVTIAKEIELSDPVENIGAKVISVAAVSTNDIAGDGTTTATILAQEMTNRGIEIINKGANPVNIRRGIEDASLLIIKELEKYSKKINTNEEIEQVAAISSGSKEIGKLIAQAMALVGKNGVITTDDAKTINTTLETTEGIEFKGTYASPYMVSDQEKMEVVLEQPKILVSSLKINTIKEILPLLEGSVENGNPLLIVAPDFAEEVVTTLAVNKLRGTINVVAVKCNEYGERQKAALEDLAISSGTLAYNNEINSGFKDVTVDNLGDARKVQIAKEKTTVIGGKGNKDKIKKHVELLNGRLKQTTDKYDSDLIKERIAYLSQGVAVIRVGGATELAQKELKLRIEDALNSTKAAVEEGIIAGGGVGLLNASCVLTNSKLKERYENETSVENIKEILLGFEIVQKSLEAPARQIIQNSGVDPVKILSELKNEKTGVGFDAETKKKVDMIANGIIDPTKVTKTALEKAASVASSLITTNVAVYDVKERKDNSFSE
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CAMJJ
Sequence: MTCLYPGTFDPITNGHLDVIKRALKIFDEVIVAIAKSEHKKPCYDLEKRKELALLATQNLKNVKIIAFDNLLVDLAKELKVNTIIRGLRAVSDFEYELQIGYANHALWEDMETIYLMPSLKHAFISSSIVRSIVAHGGDVSSLVPKEILPFLKDQSCM
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P3H2_CHICK
Sequence: MAPGSRSWGAVLLLAAMLPAACGSCGADGGPLEPFDALYASGVEAYYGGDFAGAARCLEQALRSRRELRAERLRCRRRCRGQVRLAALGAGPAGELPFFGALLRRAGCLRSCEEPRLGAASRHRAAEEVRSDFQRRVPYSYLQRAYIQLNKLEEAANAAHTFFMANPEHMEIQQDIENYKTTAGKVSLIDLEAKPHMEDYSAGVRHYDKEEYGLAITFLERALEGYYAEDEDCQIMCEGPQRFEEHEYLEYKAGLYEAIADHYMQVLACKHDCIRELATRSGRISPIENFLPLHYDYLQFAYYRVGDYVKALECARSYLLFHPDDEDVLENAAYYEGLLEGTVDPATIKPRKEAKALLRRHKLESHLLRVAAVGLGFTYTEPNYWKRYGARQDEHSVPSSISSEPEDGPRLSLTKKPTPKPDRELKEGGPLLYSDVKFVYNSQQLNGTQRVLLDNVISEEQCRELHRVASGIMLAGDGYRGKTSPHTPNERFEGATVLKALKYGYEGRVPLKSARLFYDISEKARRIVESYFMLNSTLYFSYTHLVCRTALSGQQERRNDLSHPIHADNCLLDPEANECWKEPPAYTFRDYSALLYMNADFEGGEFIFTEMDAKTVTASIKPKCGRMVSFSSGGENPHGVKAVTKGQRCAVALWFTLDPLYRELERIQADEVIAMLDQEHVGRSEMNINPKDEL
What is the function of this protein?
Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (By similarity).  Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity).  Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1.  Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline.  Has no activity on substrates that lack 4-hydroxyproline in the third position (By similarity).
What are the official names of this protein?
Prolyl 3-hydroxylase 2, Leprecan-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the leprecan family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Golgi apparatus.
Protein: OX1R_BOVIN
Sequence: MEPSATPGPQMGVPTEGRERSPEPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFFVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAVMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSVQLEEQGQGLGAEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCVSLKVPSPRSSASHKSLSLQSRCSVSKASEHVLLTSVTTVLP
What is the function of this protein?
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide.  Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.
What are the official names of this protein?
Orexin/Hypocretin receptor type 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCUP_ECOLU
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_PSEMY
Sequence: MAEVEKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDESNQCKIGDKVSIRETRPQSKTKSWALVEVVERAVEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.