PharMolix/UniProtQA huggingface dataset:
Protein: RAN_CARAU
Sequence: MAENEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKYNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVEMSALAPPEIAMDPSLAAQYEHDLKVASETALPDEDDDL
What is the function of this protein?
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs.  Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis.  Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way.  Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport.  Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins.  RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation.  Required for normal progress through mitosis.
What are the official names of this protein?
GTP-binding nuclear protein Ran, GTPase Ran, Ras-related nuclear protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Cytoplasm, cytosol. Cytoplasm. Note=Predominantly nuclear during interphase. Becomes dispersed throughout the cytoplasm during mitosis (By similarity).
Protein: MY122_ARATH
Sequence: MVRTPCCRAEGLKKGAWTQEEDQKLIAYVQRHGEGGWRTLPDKAGLKRCGKSCRLRWANYLRPDIKRGEFSQDEEDSIINLHAIHGNKWSAIARKIPRRTDNEIKNHWNTHIKKCLVKKGIDPLTHKSLLDGAGKSSDHSAHPEKSSVHDDKDDQNSNNKKLSGSSSARFLNRVANRFGHRINHNVLSDIIGSNGLLTSHTTPTTSVSEGERSTSSSSTHTSSNLPINRSITVDATSLSSSTFSDSPDPCLYEEIVGDIEDMTRFSSRCLSHVLSHEDLLMSVESCLENTSFMREITMIFQEDKIETTSFNDSYVTPINEVDDSCEGIDNYFG
What is the function of this protein?
Transcription factor involved in glucosinolates biosynthesis.
What are the official names of this protein?
Transcription factor MYB122, Myb-related protein 122, AtMYB122.
What are the subcellular locations of this protein?
Nucleus.
Protein: O162_CONTC
Sequence: MKLTCVLIISVLFLTASQLITAVYSRDKQQYRAARLRDEMRNLKGARDCGEQGQGCYTRPCCPGLECRGGGTGGGVCQQ
What is the function of this protein?
Ion channel inhibitor that inhibits the increase in intracellular calcium upon depolarization in DRG neurons.  In vivo, both intraperitoneal and intracranial injections into mice induce hyperactivity.
What are the official names of this protein?
Conotoxin Tr6.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NFI_AQUAE
Sequence: MNTELLEKLKKIQLECAKKVIARDDFEKVETIGGMDLTFEKINENPTRAWASLVVVELKTLKPVYQHVVKDIVDFPYIPTFLAFREMPLLLKLYETAKVKPDVYFIDGQGIAHPRGCGIASHFGVETGEVTVGVAKSKLFGYAKEPAPQRGSYTYLKYKGKIIGAVVRTKDNTAPVYVSVGHRISLKTAIDLVLKTSKYRVPEPTRLAHNLLQVVRRKELRR
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH3_SULTO
Sequence: MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLLDGVLIGKNDYILTKIKELSPVPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHFDLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFGGDNIGIFLGVDNINKVIELANSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: PT153_ARATH
Sequence: MADRSRIRGFLREEHVTYASILLYITLSSGQIFFNKWVLSSKEINFPYPLGLTLLHMTFSSVLCFLLTKVFKVMKVEEGMTLEIYVTSVIPIGAMFAMTLWLGNTAYLYITVAFSQMLKAIMPVAVFILGVCVGLEIMSCKMLLIMSVISFGVLVSSYGELNINWVGVVYQMGGIVSEALRLILMEILVKRKGIKLNPLSLMYYMSPCSAICLFIPWIFLEKSKMDTWNFHVLVLSLNSLCTFALNLSVFLVISRTSALTIRIAGVVKDWLVVLVSALLFAETKLTIINLFGYAVAIVGVATYNNHKPKNGESITLVSQSPKNSDKKPDGPL
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At1g53660.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LPXD_GEOSM
Sequence: MKKTLREIAEYLGGTVSGDGEVLIGGLATLDDAGEGTLTFLANPKYAAKVATTKASAVLMGTGGNTHGKNAIFHPNPYLAFAKLLTLFYTAPAKPVGVLPGAFVADGVKLGADVSVYPGASIGAGAVIGDRVVLHPGVVLYPGVVVGNDVTLHANVSVRERCRIGNRVTIHDGTVIGSDGFGYAPDGASYYKIPQIGIVIIEDDVEIGSNCVIDRAALEATRIRRGTKIDNLVQIAHNVVIGEDCIIVSQVGISGSTQLGNHVTLGGQVGVAGHIKIGDNVMIGAKSGVAGNVEPNQVLSGIPVMPHRDWLRSAGIAPKLPEMKKTLSALEKRVAELEAKLAKGE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYM_CHLMU
Sequence: MASSRILITSALPYANGPLHFGHITGAYLPADVYARFQRLLGKEVLYICGSDEYGIAITLNAELAGMGYQEYVDMYHKLHKDTLKKLGISVDFFSRTTNPHHPAIVQDFYRNLQDKGLMENLVTDQLYSEEEEKFLADRYVVGTCPKCGFDRARGDECQQCGADYEARDLKDPRSKLTGKALSLRETEHAYFHLERMKEELLTFVEGIYLRPHMRNFVIDYIKNLRPRAVTRDLSWGVPVPGLENKVFYVWFDAPIGYISGTMDWAASIGDPDAWKKFWLDDKVTYTQFVGKDNTSFHSVIFPAMEMGQSLPYKKVDALVTSEFLLLEGFQFSKSEGNIIDMDAFLETYSLDKLRYVLAAIAPETSDSEFAFQEFKTRCNSDLVGKFGNFVNRVVAFAAKNGCTELSHPQLEQQDLEFIAEAQKLAKEAADHYQQYSLRKACSTIMELAALGNGYFNDQAPWKLAKEDLWNRVRSILFCACYCQKLLALISYPIMPETAWTIWGMIAPGSLDLRSQDPERLQSIWTEAFFDYSEESFSLKEPELLFTVVE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1G_ARTSA
Sequence: MVAGKLYTYPENFRAFKALIAAQYSGAKLEIAKSFVFGETNKSDAFLKSFPLGKVPAFESADGHCIAESNAIAYYVANETLRGSSDLEKAQIIQWMTFADTEILPASCTWVFPVLGIMQFNKQATARAKEDIDKALQALDDHLLTRTYLVGERITLADIVVTCTLLHLYQHVLDEAFRKSYVNTNRWFITLINQKQVKAVIGDFKLCEKAGEFDPKKYAEFQAAIGSGEKKKTEKAPKAVKAKPEKKEVPKKEQEEPADAAEEALAAEPKSKDPFDEMPKGTFNMDDFKRFYSNNEETKSIPYFWEKFDKENYSIWYSEYKYQDELAKVYMSCNLITGMFQRIEKMRKQAFASVCVFGEDNDSSISGIWVWRGQDLAFKLSPDWQIDYESYDWKKLDPDAQETKDLVTQYFTWTGTDKQGRKFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma, EF-1-gamma, eEF-1B gamma.
Protein: GMPP3_ORYSJ
Sequence: MKALILVGGFGTRLRPLTLSFPKPLVDFANKPMILHQIEALKEVGVTEVVLAINYRPEVMLNFLKDFEDKLGITITCSQETEPLGTAGPLALARDKLVDGSGEPFFVLNSDVISEYPFAELIKFHKNHGGEATIMVTKVDEPSKYGVVVMEEATGMVEKFVEKPKIFVGNKINAGIYLLNPSVLDRIELKPTSIEKEVFPRISADAKLFAMVLPGFWMDVGQPRDYITGLRLYLDSLRKRSANRLATGAHIVGNVLVHESAKIGEGCLIGPDVAIGPGCVVEDGVRLSRCTVMRGVRIKKHACISNSIIGWHSTVGQWARIENMTILGEDVHVGDEVYTNGGVILPHKEIKSSILKPEIVM
What is the function of this protein?
Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants.
What are the official names of this protein?
Probable mannose-1-phosphate guanylyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: RL24_BUCCC
Sequence: MSYKIRSNDLVIVLTGKDKGKVGIVKKIYRSNNTVIVEGINIVKKHQKSIPEKQQSGGIISKELPIHISNVSIFNKKLKKSDKVEFFWHLGKKKRRFKSNKELIQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PYRF_METS4
Sequence: MTEPLTPRDRLIVALDMASRDEAERLIDRIGDAAAFYKIGYRLGYAGGLALAERLAASGVKVFLDLKLHDIGNTVEEGVQSLARLGAHLLTVHAYPQTMRAARRGRDSVPGSALRLLAVTVLTSYDDADLREAGYAGGVADLVASRAAAARDIGIDGIVCAATEAAAVRAVIGPDRLIVTPGIRPAGAASGDQKRVVTPAAAIRAGADHLVVGRPITEAADPRAAARSIVSEIAEA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NFM_HUMAN
Sequence: MSYTLDSLGNPSAYRRVTETRSSFSRVSGSPSSGFRSQSWSRGSPSTVSSSYKRSMLAPRLAYSSAMLSSAESSLDFSQSSSLLNGGSGPGGDYKLSRSNEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQSD
What is the function of this protein?
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber.  May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
What are the official names of this protein?
Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, axon.
Protein: EX7L_LACDB
Sequence: MDSIKGTDEKYLTVSELNWYVKQKFDRDPYLRQIFLQGELSNFRFRRGGHQYFSLKDDKSKINVVMFRGDFDKVKFEPEEGMKVYVTGRLSTYEAQGSYQFYAKSMEPSGLGALYERFRQLQEKLAKEGLFAQEHKRPLPLFPDKIAVVTSASGAVIHDIMVTANRRFPHAEIDLFPAQVQGESAAGSLVSAMQQIQARADEYDVLIIGRGGGSLEDLWPFNEEEVVRQVYAMKMPVISSVGHETDTTLCDLAADCRAATPTAAAEMATPALPLVLAEIGQLQTRLLTDIRAVIQVRAQALAQLENSFIMKEPQRLYEQKMQQVDQLSQQLSRMMEVIVKDQGQKLSLLTQRLQHQAPDRRIKQLKQENSYLAKSLEMGIKRILEQKQAACRQAVQQLDDYSPLKTLARGYSYTTDASGNVVKSVQQLVPGDQVRLHLKDGQAIGRIEEIKEEKND
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CLONN
Sequence: MKSYLAKENEVQRKWYVIDVEGKPLGRAASQVATILRGKNKPTYTPNVDTGDYVIILNAEKVALTGKKLDQKMLRHHSLYPGGLKEISYKKALESKPEFVFQEAVRRMLPQGPLGRKMLKKLKVYRGSEHNQEAQKPEVLELRY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ATP8_SCYCA
Sequence: MPQLNPSPWFIILLFSWVIFMVILPNKVMNHLFNNEPALKSTEKSKPDPWNWPWL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RK4_GUITH
Sequence: MGSNKIKNLVQYEIQDFVSLNKMDTKSHDSLNLNVSKKSRYLLHRVLTNQLINNRSGNACTKTRSEVEGGGKKPWKQKGTGNARAGSSNSPLWKGGGVTFGPKPRTFSNKTNKKERLLALTTALYLKSNNTKVINLDNLDFTNLKTRDLVIKCSNLIENYKKDQKILFVAEPTASGLWRYVKNISNVDLIYTTGLDLKKILQAHHIIFTCKALNDVKEVFNEQ
What is the function of this protein?
Probably binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHIP_ECOLI
Sequence: MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGGIYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAENGDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLLAPHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKVDYLHSFGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRDKVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYASSNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQSNPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNIFQDERDVKFMVIAPFTIF
What is the function of this protein?
Involved in the uptake of chitosugars.
What are the official names of this protein?
Chitoporin, ChiP-III.
What is the protein family that this protein belongs to?
Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: NDK_SALDC
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_SULSY
Sequence: MFVKQKSGGKKLEEKNNQENIENQEQNQEEVREEKPLTEQEKDELIKKLQEEVETLKQKLQKTEEAAKRLSALYQSIQKDFEDYKIRAIKEREQIKEESIEKFAKAFLDVVDNFEKALESFKVSNDINAIMQGIRMTHYQIMNLLQSYGIEKIEAAGEFNPMEHEALETLKTKEYRNNQIVKVLQAGYKYKGKVIRPAKVVVAISEEEEIT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBEAG_DHBVQ
Sequence: MWNLRITPLSFGAACQGIFTSTLLLSALTVPLVCTIVYDSCLYMDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQAAQGGRKTSSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: HPPK_STRP8
Sequence: MTIVYLSLGTNMRDRAAYLQKALETLADLPQTRLLAQSSIYETAAWGKTDQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFGEEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFSAQQTEF
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: NU2M_LITCT
Sequence: MNPLALTIFLLSLAIGTTITLSSFHWLLAWIGLEINTLAIIPLMTKTPHPRAIEAATKYFLTQAAASALVLFSSLISAWQTGEWSINSLMDLPMNILSIALMMKLGLAPLHFWIPEVLQGISLPTGLILSTWQKIAPMALLLQTSHLINLNLTIALGLTSIMVGGWGGIGQTQLRKIMAFSSIGHLGWIIVILKFDPQLSLLNFVLYIIMTAAMFMSLTTISATKMLEISTSWSKTPALTTTTMLILLSLAGLPPLTGFTPKLLITLELVKQNATLLAVMVMFISLLALFFYIRLTYVVTLTLSPNTPNSLLTWRTASRSYSTTAIMNTMALILLPITPTLLLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: C3H13_ORYSJ
Sequence: MLGPPRRGPAYKTKLCALWQRGNCNRDTCSFAHGHGDIRRPPSSRGAFTHHPGRRDYRAGDFRGRIDRRFSPRRRHSPGRESRGHRPLYDRRPSSRERDSSYSRSPSRKSERRHEKKTDDGETNSSRSLSLSDNNDEKKKDKFSSGDEKEDHEKQLKQIRLDMEALRDDKTQMEVILDEKIDEVRKISSKVNDLEVQLRREKDECHRMTSKMKKFIKAHARFLKAQEEVKRSQARFERLGDLLASDILKRGANEEGSSVNEDLNERSPNTAATKKRSIPYSTSEEAKAVKKRRERDSDTMTRSDKYRSDVTDFDKTSKGTEATKSLYLKKKLWEDEKSKLGANIFTEKVKGSPVRHVLPSTGMAAHAIDDLNEAIELEDRHESIDALLENDADDKTRSPAIPLQPPPVVQNAYEQYEGDDEEVDVE
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 13, OsC3H13, BRI1-kinase domain-interacting protein 105, BIP105.
Protein: YKVQ_BACSU
Sequence: MFQMSYYYSGLGWDFIQHVDQTNGVLNVVSPDFFYIRKDGSLLLRSANPDVIKALHRRKLKVVPFLSNHWDQDLGRFALMNRVLLAKQISHAIEELDLDGVNIDIENLTEKDRNLFTDFIRLVRKSIPRHKEVSVAVAANPFGWTKGWHGSYDYEYLAKYADYLMVMAYDESRLAGPTASVGWVEKSIQYVLTQKISPQKLVLGLPFYGRCWMEGQSASQAIPLYLVVSKKA
What are the official names of this protein?
Putative glycosylase YkvQ.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: TBP_HUMAN
Sequence: MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473, PubMed:27193682, PubMed:2194289, PubMed:2363050, PubMed:2374612).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473, PubMed:27007846).  The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (PubMed:33795473).  TBP forms the TFIID-A module together with TAF3 and TAF5 (PubMed:33795473).  TBP is a general transcription factor that functions at the core of the TFIID complex (PubMed:33795473, PubMed:27193682, PubMed:2194289, PubMed:2363050, PubMed:2374612, PubMed:9836642).  During assembly of the core PIC on the promoter, as part of TFIID, TBP binds to and also bends promoter DNA, irrespective of whether the promoter contains a TATA box (PubMed:33795473).  Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071).  Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC during RNA polymerase I-dependent transcription (PubMed:15970593).  The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter (PubMed:15970593).  SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA (PubMed:15970593).
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.