PharMolix/UniProtQA huggingface dataset:
Protein: VAP_CAMVS
Sequence: MANLNQIQKEVSEILSDQKSMKADIKAILELLGSQNPIKESLETVAAKIVNDLTKLINDCPCNKEILEALGTQPKEQLIEQPKEKGKGLNLGKYSYPNYGVGNEELGSSGNPKALTWPFKAPAGWPNQF
What is the function of this protein?
Plays a role in virus cell-to-cell and plant-to-plant transmission.  Interacts with virion icosahedral capsid and movement protein, thereby facilitating virion cell-to-cell transmission through plasmodesmata opened by viral movement protein.  Also interacts with aphid transmission factor, attaching the virion to aphid stylet when the animal feeds on an virus infected plant.  Aphid saliva may later detach the virion, inducing release of infectious particles when the animal feeds on a new plant.
What are the official names of this protein?
Virion-associated protein, Vap, Protein 3, P3.
What is the protein family that this protein belongs to?
Belongs to the caulimovirus ORF III family.
What are the subcellular locations of this protein?
Virion. Host cell junction, host plasmodesma.
Protein: PDF1_CAEEL
Sequence: MNRFIISMIALLAVFCAVSTASPLLYRAPQYQMYDDVQFVKRSNAELINGLIGMDLGKLSAVGKRSNAELINGLLSMNLNKLSGAGRR
What is the function of this protein?
Probable ligand of isoforms a and b of the calcitonin receptor-like protein, pdfr-1, a G-protein coupled receptor (PubMed:18390545).  May not signal through isoform c of pdfr-1 (PubMed:18390545).  Involved in locomotion; more specifically mate searching behavior of males, independent of nutritional status (PubMed:18390545, PubMed:22579613, PubMed:23143519, PubMed:30024377).  Involved in regulating the male-specific expression of TGFbeta-like daf-7 in the ASJ chemosensory neurons (PubMed:30024377).  Plays a role in circadian rhythms of locomotor activity (PubMed:26113231).  Involved in mediating arousal from the sleep-like state called lethargus, which occurs during molting between larval and adult stages, in part by regulating touch sensitivity, and working in concert with neuropeptide flp-2 (PubMed:23764289, PubMed:27585848).  In the presence of food, plays a role in initiating and extending exploratory roaming behavior, in opposition to 5-hydroxytryptamine (serotonin) signaling.
What are the official names of this protein?
Pigment dispersing factor homolog pdf-1.
What are the subcellular locations of this protein?
Secreted.
Protein: HPAB1_PSESG
Sequence: MPGINGAGPSNFFWQWRTDGEPVTEREHDSSRSASSANSPEFPPPASPAESGRQRLLRSSALSRQTREWLEATPARVQGATPPAEARQSPEAQQAERIVQELVRGGADLNNVRTMLRNVMDNNAVAFSRVERDILLQHFPNMLMTGISSDSVLANELRQRLRQTVRQQRIQSSTPARLADSSSGSSQRSLIGRSTMLMTPGRSSSSSAAASRTSVDRHPQGLDLESNEVLRRLTQEGVDMERLRTSLGRYIMSLEPLPPDLRRALESVGINPFMPEDLSLVDHPVLNFSAALNRMLASRQTTTNSPELPPLASSAESGRRRLLRSPPLLSGQREWIEQNMRQEAEPQSSRLNRAVRLAVMPPQNENEDNVAYAIRLRRLNPGADVSRVVASFITDPAARQQVVNDIRAALDIAPQFSQLRTISKADAESEELGFRDAADHPDNATSCLFGEELSLSNPDQQVIGLAVNPTDKPQPYSQEVNKALTFMDMKKLAQYLADKPEHPLNRQRLDAKNIAKYAFKIVP
What is the function of this protein?
Effector protein that plays different roles depending on the species and plant cultivars that interact with the pathogen.  Acts as a virulence determinant by enhancing the development of disease symptoms and bacterial growth.  Acts as an avirulence factor by eliciting hypersensitive response (HR) and plant resistance.
What are the official names of this protein?
Effector protein hopAB1, Protein virPphAPgy.
What is the protein family that this protein belongs to?
Belongs to the HopAB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS).
Protein: DCTA_ERWT9
Sequence: MKPSLFKSLYFQVLAAIAIGVLLGHFNPELGAQMKPLGDGFVKLIKMIIAPVIFCTVVSGIAGMESMKAVGRTGAVALIYFEVVSTIALIIGLVVVNVLQPGAGMNVDPATLDAKAVAMYAQQAEQQGVVAFLLDVIPGSVIGAFASGNILQVLLFAILFGFALHRMGDKGTLVFNFIDSFSHVFFGIINMIMRLAPVGAFGAMAFTIGKYGVGSLVQLGQLIVCFYITCLLFVVVVLGLIARVVGFNIFKFIAYIKEELLIVLGTSSSESALPRMLAKMENLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIWHQITLLVVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATLVVAKWVGQLDEKKLKEQLVHRKNEVKSV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_AKKM8
Sequence: MAKEQFQRNKPHVNVGTIGHVDHGKTSLTAAITSVLAKKGFAEARGYDQIDAAPEERERGITISTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAASDGPMPQTREHILLARQVGVPAIVVYMNKCDLVDDPDLLELVEMEIRELLNEYEFPGDDTPIIKGSAVKALEGDAAAEDSIMELMAAVDSYIPQPERPVDQPFLMPVEDVFSISGRGTVATGRIERGVIKKMEEVEIIGIKDTQKTAVTDIEMFRKLLDEGQAGDNVGLLLRGLKKEDIERGQVIIKPGTVKPHKNFKAEVYVLTKEEGGRHTPFFNNYRPQFYFRTTDVTGCCTLPEGVEMVMPGDNVNLEVQLITPIAMEKAMRFAIREGGRTVGAGRISEILD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_TRIEI
Sequence: MIFYNRVINKGQLKKLISWSFNNYGTAITAQMANKLKDLGFRYATKAGVSISVDDLQVPPSKRQLLDEAEQEIRNTTERYTKGKITEVERFQKVIDTWNSTSENLKNEVVRNFRSTDPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIVREADCGTKRGVMVTSMKDGDRVLIPVKDRLLGRVLADDVKDPKTGEIVTQGHIQAVKNQVLTEDLAKAIGKAGVENVFVRSPLTCESPRSVCQTCYGWSLAHGHMVDMGEAIGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVARQFVASFGGVVKYPSNVRTRSFRTRHGDEAMIAENNFDMIILGVDGRKETIPIAQGSILMVQNNQQVSAGIVLAEVPKVGQVRKTTEKVTKEVASDLAGELKFAQLVQEEKVDKQGTTTRIAQRGGLIWILEGEVYNLPPGAEAMVKNGTRININSVLAETKLVTEHGGVIRISSSPLYSPEKQNETNVLAQATQESTIDELEASMTGTSAQLPINTEMPDNLPREIEVITASVRLDQAKVRLESISNREQYIIETQNDQRFALKVTPGSKVGNHEVIAELLDENYQTSTGGIIKYAGVEVLKRGKAKQGYEVVKGGTLLWIPEECHEVNKDISLLLVEDGQYVEAGTEIVKDIFCQSNGVTEVHQKNDILREVVIKPGKLHSGNYEIDLGDLTLMDGQIATPGEEVIPGLVTSELKYIEYIETPEGPGLLLRPVTEFHVPDEPGVPSQKSINSSIELRAVQRIPFKDGERVKSVEGIELLRTQLVLEIGEEAPQLAADIELLPDLEEEGIMRLQLVILESLVIRRDVVADTTQGSTSTRLLVKDGDVIEAGGVVSRTQILSKKSGEVRGIREGSEAIRRILIVREADLVKIPVNTLPSVVEGDLLVAGTEIAPGIVIPRSGLVSKVEETVLNDGSKGYQVILRKGRPYRVSTGAVLLTMDGDLVQRGDILVLLVFERTKTGDIIQGLPRIEELLEARKPKESCILVKYPGQAQVNVNDDNVEVSVVSSDGTITDYPLGHGQNVIVADGQNVNVGEALTDGPQNPHEILETFFNYYREHESAYEACLRSFEACQRFLVNQVQAVYQSQGIDISDKHIEVIVRQMTAKVRIDDGGDTTMLPGELIELRQVEQVNEAMSITGGATAQYTPMLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFNAYEDALSAEINRLEQNWDDDLDIFEEGDLQSVVLDDQTARSLEFENSLNLSSANQNFVDSQGKPQSQSSFIDDSMSEFSPVKDKSGSVLDDSDFPPGNFDSDFPADNYDLEHEIDLEDDVYDGYDDFDENTPDLI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: DAPB_SHEPW
Sequence: MTERVRVAITGGSGRMGRTLIEAAKQNDAILLGAAIERAGSTLMGVDAGELAGVGAMNVAITDSLDKAVDDFDVLIDFTSPEASVIHTDWCAKHGKAIVIGTTGFNHAQKEQISAYSEQVPIVMAPNMAVGVNLMWKLLEVAAEVMGHYSDIEIIEGHHRYKKDAPSGTALKMGEVIAETLGRDLEKCAVYGREGITGERDRETIGFATVRAGDIVGEHTALFADIGERLEITHKASSRMTFANGAMRAASWLSAQGSGLYDMQQVLGLKE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORTL_BPPHE
Sequence: MPKWLDKALGIEKSSIEETRNMENYKMHLREIDTNVVNNEPYSMESIEKGMNGKTTAYMQPIIGEMSVNPGYKTKPSIRNSQDLHKTLKKFGNNIILNAIINTRSNQVSMYCKPARNSETGVGYEIRLKDIEAEPTSHDIANIKRIESFLENTAQFRDPNRDNFTTFCKKLVRATYMYDQVNFEKVFDKDGNFIKFDTVDPTTIFLATNGEGKLIKNGERFVQVIDNRIVAKFNERELAFAVRNPRADIEVGQYGYPELEIALKQFIAHENTEVFNDRFFSHGGTTRGILHVKTGQQQSQQALDIFRREWRSSLAGINGSWQIPVVSAEDVKFVNMTPSANDMQFEKWLNYLINVISALYGIDPAEINFPNNGGATGSKGGSLNEGNSKEKMQASQNKGLQPLLRFIEDTVNTYIVAEFGEKYQFQFRGGDLSAQLDKLKIIEQEGKVFRTVNEIRHDKGLEPIKGGDVILNGVHIQAIGQALQEEQLEYQRSQDRLNRLLELSGGDVEQPEPEEPKDSQNDTDVSFQDEQQGLNGKSKKVNGKVDDNVGKDGQLKSEENTNSTKHGTDGIKKE
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.
What are the official names of this protein?
Probable portal protein.
What is the protein family that this protein belongs to?
Belongs to the phage portal family.
What are the subcellular locations of this protein?
Virion.
Protein: BLAC_BACSU
Sequence: MKLKTKASIKFGICVGLLCLSITGFTPFFNSTHAEAKSIEDTNMASCITNKKFVQLEKKFDARLGVYAIDIGSNKTIAYRPNERFAYASTYKVLAAAAVLKKNSIEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGPKGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRMILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNRFTKDANYDNALIAEAAKVVLNDLK
What is the function of this protein?
This protein is a beta-lactamase with a substrate specificity for penicillins.
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_MYCTO
Sequence: MTDTQVTWLTQESHDRLKAELDQLIANRPVIAAEINDRREEGDLRENGGYHAAREEQGQQEARIRQLQDLLSNAKVGEAPKQSGVALPGSVVKVYYNGDKSDSETFLIATRQEGVSDGKLEVYSPNSPLGGALIDAKVGETRSYTVPNGSTVSVTLVSAEPYHS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y1533_BRAHW
Sequence: MSGHSKWASIKHKKAANDSKKGKIWSKIAKEITIAVKEGGSPDPDQNARLRMVIVKAKGTNMPNDNIDRAIKRGAGAGEGANIEEMSYEGYAPGGVAIIVDVATDNKNRTAAEIRSIFSKNGGNLAENGAVSWQFKKKAVVMIPAAGNTEESLMDIVLDAGAEDIEQDEEVFTITGPMETLSSIVDALKAKGIEPESAEIVRVADNTMTIAENDAKKVMKIIGLFEDHDDVSAVATNLEITDNLIEE
What are the official names of this protein?
Probable transcriptional regulatory protein BHWA1_01533.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB076_XENTR
Sequence: MMPGGATVTVRLVRSFEHRNFRPVVYHGVNLDQTVREFIVQINEDIPHRAALPLPFKKYSYDTLKIIHQPHGAKTNELVVGLEDDERLILAPGGTLREAGVAHETELAFFCHKDYQTYKANPVSKW
What are the official names of this protein?
UPF0538 protein C2orf76 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0538 family.
Protein: DNAK_PECCP
Sequence: MGKIIGIDLGTTNSCVAIIDGTQVKVLENSEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPKNTLFAIKRLIGRRFKDEEVQRDANIMPYKIIAADNGDAWLEVKDQKMAPPQISAEVLKKMKKTAEDYLGETISEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRMINYLVDEFKKEQGFDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHLNIKVTRAKLESLVEELVNRSLEPLKVALQDAGLSVSEIQDVILVGGQTRMPLVQKKVADFFGKEPRKDVNPDEAVAIGAAVQGGVLSGDVKDVLLLDVTPLSLGIETMGGVMTALIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAHDNKSLGQFNLDGIQAAPRGMPQIEVTFDIDADGILHVSAKDKNSGREQKITIKASSGLNEEEIQKMVRDAEANAEADRKFEELVQARNQGDHLLHSTRKQLEEVGDKLAADDKTAIDDALKALESALKGEDKAEIEAKIQALVQVSGKLLEASQPQPGAEGAADDASARRDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DHX15_MOUSE
Sequence: MSKRHRLDLGEDYPSGKKRAGTDGKDRERDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHTGHTGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQSKEYSQY
What is the function of this protein?
RNA helicase involved in mRNA processing and antiviral innate immunity (PubMed:26494172, PubMed:34161762).  Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA (By similarity).  In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns (By similarity).  Plays a key role in antiviral innate immunity by promoting both MAVS-dependent signaling and NLRP6 inflammasome (PubMed:26494172).  Acts as an RNA virus sensor: recognizes and binds viral double stranded RNA (dsRNA) and activates the MAVS-dependent signaling to produce interferon-beta and interferon lambda-3 (IFNL3) (By similarity).  Involved in intestinal antiviral innate immunity together with NLRP6: recognizes and binds viral dsRNA and promotes activation of the NLRP6 inflammasome in intestinal epithelial cells to restrict infection by enteric viruses (PubMed:26494172, PubMed:34678144, PubMed:34161762).  The NLRP6 inflammasome acts by promoting maturation and secretion of IL18 in the extracellular milieu (PubMed:34161762).  Also involved in antibacterial innate immunity by promoting Wnt-induced antimicrobial protein expression in Paneth cells (PubMed:33483420).
What are the official names of this protein?
ATP-dependent RNA helicase DHX15, DEAH box protein 15.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: SYR_STAA9
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLAAHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA2_PSESM
Sequence: MSTLSPRRSAILTFIRDRIAQQGQSPSLAEISEAFGFASRSVARKHIVALTEAGLIEVVAHQARGIRLLNSEPRPELLEIPVLGRVAAGAPIGPDLDIHTTLHLDRSTFTRVPDYLLRVQGDSMIEDGILDGDLVGVHRNPQASDGQIVVARLEGEVTIKRLQHRGDQLHLLPRNPAYQPIIVTPDQDFAIEGVFCGLVRRE
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CHIA_RAT
Sequence: MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNNQITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPLYKLPTETGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLRNGATQDWDAPQEVPYAYKGNEWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNKALDIPTAGCTAPDLPSEPVTTPPGSGSGGGSSGGGSEGSGFCAGKADGLYPVADDRNAFWHCINGITYQQHCQAGLVFDTSCNCCNWP
What is the function of this protein?
Degrades chitin and chitotriose.  May participate in the defense against nematodes, fungi and other pathogens.  Plays a role in T-helper cell type 2 (Th2) immune response.  Contributes to the response to IL-13 and inflammation in response to IL-13.  Stimulates chemokine production by pulmonary epithelial cells.  Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1.  Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding (By similarity).
What are the official names of this protein?
Acidic mammalian chitinase, AMCase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted.
Protein: Y8577_ORYSJ
Sequence: MYMDLTLGGALLQVEEATEEEEEEEEEEQALGQEPAPAAAAAALVLGRRHGVVVGGGGGGVVVAAEREHMFDKVVTPSDVGKLNRLVVPKQHAERFFPAAAAGTQLCFEDRAGTPWRFRYSYWGSSQSYVMTKGWSRFVRAARLSAGDTVSFSRAADGRYFIDYRHCHRHGGRDISFASAATAMPAAAWPLFGRVQTAAPVSYGGGHGSAAAATMFLDTVAPVAAAGGHRGEVGPSGQRSFRLFGVNVECGGDVDAAAEEEDADDDVDDGDHRRGEEMELVMWTNHR
What are the official names of this protein?
Putative B3 domain-containing protein Os08g0157700.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTA_ECOBD
Sequence: MQDAVPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: RL11_CARHZ
Sequence: MAKKVVAVVKLQIPAGKATPAPPVGPALGQHGVNIMAFVKEYNERTAQQAGMIIPVEITVYEDRSFTFVTKTPPASDLLKKAAGIESGSGQPNKKKVGKVTRAKIREIAELKLKDLNANDVEAAMRMIEGTARSMGIEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: QPCT1_DROME
Sequence: MAIGSVVFAAAGLLLLLLPPSHQQATAGNIGSQWRDDEVHFNRTLDSILVPRVVGSRGHQQVREYLVQSLNGLGFQTEVDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFPNDPGFVGATDSAVPCAILLNTAKTLGAYLQKEFRNRSDVGLMLIFFDGEEAFKEWTDADSVYGSKHLAAKLASKRSGSQAQLAPRNIDRIEVLVLLDLIGARNPKFSSFYENTDGLHSSLVQIEKSLRTAGQLEGNNNMFLSRVSGGLVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYLKRHTSPVNLRFYRT
What is the function of this protein?
Acts as a glutaminyl-peptide cyclotransferase (PubMed:17722885, PubMed:22897232).  Responsible for the biosynthesis of pyroglutamyl peptides (By similarity).  Might be more efficient in the conversion of tri and tetrapeptides in vitro (PubMed:17722885).  Might have a relative preference for substrates containing hydrophobic amino acids in vitro (PubMed:17722885).
What are the official names of this protein?
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the glutaminyl-peptide cyclotransferase family.
Protein: DDL_HELPH
Sequence: MEFCVLFGGASFEHEISIVSAIALKGVLKDRIKYFIFLDENHHFYLIEASNMHSKYFAQIKEKKLPPLILTHKGLLKNSFLGAKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRIEASVLSYNKYLTKLYAKDLGIKTLDHVLLNEKNRANAMDLINFNFPFIIKPNSAGSSLGVSVVKEEKELNYALDSAFEYSKEVLIEPFIQGVKEYNLAGCKIKKDFCFSYVEEPNKQEFLDFKQKYLDFSRTKAPKANLSNALEEQLKENFKKLYNDLFDGAIIRCDFFVIENEVYLNEINPIPGSLANYLFDDFKTTLENLAQSLPKTPKIQIKNSYLLQIQKNK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_PSEFS
Sequence: MNSLYIAGSWLAGQGELFESRNPVTQHVLWAGNGATAEQVESAVQAARQAFPAWARRPLEERISVLETFAATLKNRADEIARCIGEETGKPLWESVTEVTSMANKIAISVQSYRERTGEKSGPLGDATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVLFKPSELTPKVAELTVQCWIEAGLPAGVLNLLQGARETGIALAANPGIDGLFFTGSSRTGNHLHQQFSGRPDKILALEMGGNNPLVVDEVADVDAAVYTIIQSAFISAGQRCTCARRLLVPEGAWGDALLARLVAVSATIAVGAFDQQPAPFMGSVISLAAAKALMDAQELMLANGAVALLEMTQPQDQAALLTPGIIDVTGVTAREDEELFGPLLQVIRYADFAAAIAEANNTQYGLAAGLLSDSEARYQQFWLESRAGIVNWNKQLTGAASTAPFGGVGASGNHRASAYYAADYCAYPVASLETPSLVVPATLTPGVRLS
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RCO1_CHAGB
Sequence: MAHIHDLAASLAPNYTANRLTTPTPTRFPRTPTFASMNKPCRFEGTVDDLEVTGTIPADLDGTFFRVQPDHRFPPLFEDDIHFNGDGAVTAVRIENGRAALRQRYVRTDRFEKEARAGRSLFGRYRNPWTDNESVKGVIRTASNTNVVFWRGVLLAMKEDGPPFAMDPVTLETLGRYDFEGQIVSPTFTAHPKVDPRTGEMVCFAYEAGGDGSDCSVDVAVWTVNGDGRKVEECWYKAPFAGMIHDCGISENWVVLALTPIKMNLERMKRGGNKFAWDPNEDQWYGVVPRRGAKSEDIIWFRADNAFHGHVAGCYELPSGEIVFDLTVADGNVFFFFPPDDNITPPDGIAKRNKLSSPTTRWIFDPKAKKSAIRTLDARDADVWVADERVKPTLTWLTNGEFSRIDERYNTKPYRHFWQAVVDPTKPYDFAACGPPAGGLFNCLGHYTWSGKNYHTGESTENGASGEGEGDGKFGLEDVYFSGPTMTFQEPTFIPREGGAEGEGYLIALLNHLDQLRNDVVIFDAQNLAKGPVAVIHLPLKLKLGLHGNWVDHRDIDAWQKRRSEDGDIGPVQVAKEPLPWQKKLAEQKGETGL
What is the function of this protein?
Dioxygenase that cleaves the interphenyl C-alpha-C-beta double bond of resveratrol to yield 3,5-dihydroxybenzaldehyde and 4-hydroxybenzaldehyde (PubMed:21073977).  Cleaves also piceatannol, a compound that differs from resveratrol only in the occurrence of an additional hydroxyl group, which leads to the production of 3,4-dihydroxybenzaldehyde and 3,5-hydroxybenzaldehyde (By similarity).
What are the official names of this protein?
Resveratrol cleavage oxygenase 1, RCO 1.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.