Protein: PKD1_CAEEL
Sequence: MKKSNFFVLLLLAISAIQIDGLHYQLLDGIATFRLDNDDTTIGGVPRNSQGVVKIKLSCGLNRLSVENKVTEVSSLELIHNCIQTETRLVGLFLNSTWITLNEVNDDDEISIAVEAKYEVCYDDGIDRCDGSLWWLQVGGNEMALLGYREKCESGEINEEYARRMCKRPYRSEKSTAISDSQGVYYDGQVLKGVRAKQFSMRTSGSPTLRRMKRDAGDNTCDYTIESTSTSTTTPTTTTVTSTVTSTTTVPTSTSTVTTAMSTSTSTPSTSTTIESTSTTFTSTASTSTSSTSTTQQSSSTITSSPSSTTLSTSIPTTTTPEITSTLSSLPDNAICSYLDETTTSTTFTTTMLTSTTTEEPSTSTTTTEVTSTSSTVTTTEPTTTLTTSTASTSTTEPSTSTVTTSPSTSPVTSTVTSSSSSSTTVTTPTSTESTSTSPSSTVTTSTTAPSTSTTGPSSSSSTPSSTASSSVSSTASSTQSSTSTQQSSTTTKSETTTSSDGTNPDFYFVEKATTTFYDSTSVNLTLNSGLGIIGYQTSIECTSPTSSNYVSTTKDGACFTKSVSMPRLGGTYPASTFVGPGNYTFRATMTTDDKKVYYTYANVYIQEYSSTTIESESSTSAVASSTSSTPSTPSSTLSTSTVTEPSSTRSSDSTTTSAGSTTTLQESTTTSEESTTDSSTTTISDTSTTSSSPSSTTADSTSTLSVDQFDFILDSGLSWNETRHNEDSINIVPLPTNAITPTERSQTFECRNVSTEPFLIIKESTCLNYSNTVLNATYSSNIPIQPIETFLVGIGTYEFRINMTDLTTMQVVSHIFTLNVVADSTSTSEVTSTTSTGSSSESSAISTTSGIESTSTLEASTTDASQDSSTSTSDSGTTSDSTTIDSSNSTPSTSDSSGLSQTPSDSSSASDSMRTTTVDPDASTETPYDFVLENLTWNETVYYSENPFYITPIPNKEPGALTTAMTCQCRNDSSQPFVLLKESNCLTEFGKNGAYSASVSFNPMTSFVPATGTYEFLINVTNRASGESASHIFTMNVVLPTTTTETPPTTVSSSDDAGGKTGGTGATGGTGGTGSGGSATTLSTGDAVRSTTSGSGSGQSSTGSGAGGSGTTASGSGSGGSSGTGSDGVNSGKTTALNGDGTGSGTATTPGSHLGDGGSTSGSGSDSNGSSGVSTKSSSGSDTSGSSDSSGANGAFSATAQPSTRTTKTRSSLATVSPISAAEQAIIDAQKADVMNQLAGIMDGSASNNSLNTSSSLLNQISSLPAADLVEVAQSLLSNTLKIPGVGNMSSVDVLKTLQDNIATTNSELADEMAKVITKLANVNMTSAQSLNSVLSSLDLALKGSTVYTLGVSSTKSKDGTYAVIFGYVIASGYTLVSPRCTLSIYGSTIYLTGDTRASYKQLDGDTVTADTMLAAAIGIQGMFATNGRTVQVEQDKIDDKRSLVSGNIMATMSGVGDVQSGEYSYNDMYVTAWNVTYDNSTVGSTSQKNTSFSFNIPVSEVQYILLIESGTMIKLHSTQNIVSRGLVVTASYGGVTYTITCTNGTGKFVEVDTDNAIFSYNADSFTVVASDGSSASTVKKLIQMPIVIENVNLALFNQTTSPLVFSNAGSYSMRMVLSPQDIGIPAVSALSQTVSISTLSPTASYTKDDLQSLIKEQTLVTVSGTLFFSKASSIDVSGYSFFVDSTALYLSNSVTTLVISSPTYNIVSLALGGYGIQITAGTYTSGSQTHTVTLMEFSDTQKMRIDGGLIIRNGTNGYVIQNGQVSTEGDVSGTKIDIVPQSLMNQESQQQIETILSNTQDFLTNNGMTMTDAEINDTSNSLLSIAGSLTSALKIALDNPLSSDLAANLKYATDNYDSLYNVLPSDPDNIVYVEEMTSEEWAAYVTKMFQKNIAKNLANQLASTLDTLENTLAARAIATGNLPYDYSNSVDGTGMVIVIDDASNIVGKTQNCEEWAFKLPSPASTLNTAEITDKTLIQVGLVCYATNPRTYVDNFDMLITSGALEAHIKDENQIIIPITGTTAPIYVNGRGSEDDAVLTLMQQGDFASYQILDLHAFRTTNWNNSLQVEIIASQDYEIPNNDDTYMFSSFQSLPGPLESNHEWIFDLNTLNKTSNYFVTAGNLINNTGLFFIGIGKRNSSTNTGNSSDIVNYGQYDSMQWSFARSVPMDYQVAAVSKGCYFYQKTSDVFNSEGMYPSDGQGMQFVNCSTDHLTMFSVGAFNPTIDADFSYNYNVNEIEKNVKVMIAAVFMLVVYGCLTINAIICQRKDASRGRLRFLKDNEPHDGYMYVIAVETGYRMFATTDSTICFNLSGNEGDQIFRSFRSEEDGNWEFPFSWGTTDRFVMTTAFPLGELEYMRLWLDDAGLDHRESWYCNRIIVKDLQTQDIYYFPFNNWLGTKNGDGETERLARVEYKRRFLDESMSMHMLAQTISWFAMFTGGGNRLRDRVSRQDYSVSIIFSLVVVSMISITILKSDNSIISDSKSVSEFTFTIKDIAFGVGFGVLITFLNSLHILLCTKCRSHSEHYYYKKRKREDPEFKDNSGSWPMFMAGMARTIIVFPVLMGLIYISGAGMSLMDDLANSFYIRFLISLILWAVVFEPIKGLIWAFLILKTRKSHKIINKLEEALLRAKPAETFLRNPYGKIEKGLGTEIADVTKLRDTENRKMRDEQLFITIRDMLCFFASLYIMVMLTYYCKDRHGYWYQLEMSTILNINQKNYGDNTFMSIQHADDFWDWARESLATALLASWYDGNPAYGMRAYMNDKVSRSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGNSYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSVLYAVLGNKMGGYRSLMATFQTALAGMLGKLDVTSIQPISQFAFVVIMLYMIAGSKLVLQLYVTIIMFEFEEIRNDSEKQTNDYEIIDHIKYKTKRRLGLLEPKDFAPVSIADTQKDFRLFHSAVAKVNLLHHRATRMLQTQGQYQNQTVINYTLSYDPVSAIHETGPKRFQKWRLNDVEKD
What is the function of this protein?
Required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location.  Acts in the same pathway as pkd-2 and atp-2 in response behavior.  May be required for ciliary targeting of pkd-2.
What are the official names of this protein?
Location of vulva defective 1, Polycystic kidney disease 1 protein homolog, Polycystin-1.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=localizes to both the ciliary base and cilium proper.