PharMolix/UniProtQA huggingface dataset:
Protein: OTE_DROME
Sequence: MADVDDFDSLSNAELRAKMLAQGLPNIPVTDSSRKVLVKRLRASIGGQASPAASPKKTNRRETLAPAPGAPSAPAAASTPVDKLDGNKVAPATKARRTITAAEAKEPVRRLPEEAIRRRPDEADRLRSEEPVAARKPTTAPAAQPVQTRRTSTSSGSERKVVEPLRKPETIVEQPASSKRADREENYLKVNSLIVLESDEEEDEQLVQAADLVEQEHAARQKTTKLASSGTTTYEYKSKVVEPPRRQVYEATAAPVLPPSVPSARAQTTSSTRSYDYASNPAPGRYSSFVRTAAQGYVTAEAPPVASYSSSYKRTYANELSDDTDSKEDQYESTFARNLARLRAERIGDRISPYSRRTLASGNAGSGSLGYEPRARRSLRPNDNSVSEAFNRWLNSLEQKYHIKSKLFIVLLVLLLIGVYYIFY
What is the function of this protein?
Inner nuclear membrane protein (PubMed:2186029, PubMed:9199347, PubMed:18410727, PubMed:22751930).  Involved in the attachment of membrane vesicles to chromatin during nuclear assembly, and is probably required for centrosome maturation and cell cycle progression during mitosis (PubMed:9199347, PubMed:22751930).  Essential for differentiation of certain tissues and the maintenance of progenitor cell populations (PubMed:18410727, PubMed:24700158, PubMed:23806619, PubMed:27174470).  Required for the differentiation and maintenance of male and female germline stem cells (GSCs), as well as the maintenance of somatic cells in the GSC niche (PubMed:18410727, PubMed:23806619, PubMed:27174470).  This role is likely to be independent of the BMP (Dpp) pathway that negatively regulates bam transcription during GSC differentiation (PubMed:18410727, PubMed:23806619).  During development, plays essential and redundant functions with the other LEM domain proteins; bocks and MAN1 (PubMed:24700158).  Also has a redundant but important role with bocks during larval development (PubMed:24700158).
What are the official names of this protein?
Otefin, LEM domain-containing protein Otefin.
What are the subcellular locations of this protein?
Nucleus inner membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nucleoplasm. Cytoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Component of the spindle envelope during early mitotic cycles (PubMed:2186029, PubMed:2517292). Following nuclear envelope breakdown, becomes dispersed in the cytoplasm and concentrated at the spindle poles (PubMed:22751930, PubMed:2517292). At anaphase (when the nuclear envelope begins to reassemble), locates to the chromosomes accumulating first in areas adjacent to centrosomes and at the peripheral sites of the chromosomes (PubMed:22751930, PubMed:2517292). At telophase, expressed as a continuous rim around the chromatin and increased expression in the midspindle area (PubMed:22751930). During cytokinesis, locates to the nuclear periphery with some remaining in the cytoplasm and at the mid-body (PubMed:22751930). At stage 4 of egg development, expression in the oocyte nuclear envelope is higher than in the nurse nuclear envelope (PubMed:9199347). Expression in oocyte cytoplasm increases after stages 6 to 7 of egg development (PubMed:9199347).
Protein: RNL2_CHICK
Sequence: ETRYEKFLRQHVDHPRTLGLMGHRYCAVMLARRQVTAPGRPCKPSNTFVHAPAEDLVATCTRPADATGFHSTSTPMDITACRLRGGDTRPPCNYRARQLHHHVRVSCLDGLPVHLAGTHAS
What is the function of this protein?
Pyrimidine-specific nuclease with preference for C.
What are the official names of this protein?
Ribonuclease CL2, RNase CL2, Poly C preferential ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3110_YERPN
Sequence: MSIENTLPTYPSLALALSQQAVALTPAEMHGLISGMLCGGSKDNGWQTLVHDLTNEGVAFPQALSLPLQQLHEATQEALENEGFMFQLLIPEGEDVTVFDRADALSGWVNHFLLGLGMLQPKLAQVKDEVGEAIDDLRNIAQLGYDEDEDQEELAQSLEEVVEYVRVAAILCHIEFTQQKPTAPEMHKPTLH
What are the official names of this protein?
UPF0149 protein YPN_3110.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: TC754_ARATH
Sequence: MEAVKEAVRKIKSLVIPHADEKDNGIVFEIKLNETDQRVEKWGLDPSLDFFEVTGNCNLGRPNSEGSNQSLMGSVTIRNIFNPKLDDLLSKIEYVRFLEAVKKPRNRTFKTSFFNSRKLSPVFTGGPGYEDLVPPMFVGRDCLKATITENLTRQRELTYGVMFEEIITRDENRRISENGLLLSPDGGISINGPPTTLSGTGIDHIATLQANITRDNTKLVNGAVVGEKNIFQVDQGLGIGNNFPLFNRHQLSLTSFIQLKQVEEGSDKPQPPVLVLHGRYGGCIGDLPSYDVFALGGPNSVRGYSMGELGAAKNILELGAEIRIPVKNTHVYAFAEHGNDLGSSKDVKGNPTGLYRKMGHGSSYGLGVKLGMVRAEYTVRHNRGTGALFLRFGERY
What is the function of this protein?
Mediates the insertion of proteins targeted to the outer membrane of chloroplasts.  Required for the import of protein precursors into chloroplasts.  Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane (By similarity).  Required for etioplast formation and/or etioplast-chloroplast transition during deetiolation.
What are the official names of this protein?
Protein TOC75-4, chloroplastic, 75 kDa translocon at the outer-envelope-membrane of chloroplasts 4, AtTOC75-IV.
What is the protein family that this protein belongs to?
Belongs to the TOC75 family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Multi-pass membrane protein.
Protein: RPOB_ACOCL
Sequence: MPRDGNEGMFTIPGFSQIQFEGFCRFIDQGLMEEFHKFPKIEDTDQEIEFQLFVERYQLVEPLIKERDAVYESLTYSSELYVPAGLIWKTGRDMQEQTIFIGNIPLMNSLGTFIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTSTIISDWGGRSELEIDRKSRIWARVSRKQKISILVLSSAMGSNLREILDNVCYPEIFLSFLNDREKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQSNTFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENAVRGTICGAIRHKLILTPQNLVSSTSLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSIESPFYEVYQRSKETKMVFLSPSRDEYYTVATGNSLALNRGGIQEEQIVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVSAIAECEGKIIYTDTHKIVLSGHGDTISIPLVMYQRSNKNTCMHQNPQVRRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPERITHEIPHLEAHLLRNLDRNGIVALGSWVETGDILVGKLTPQTANESSYAPEDRLLRAILGIQVSTAKETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILSRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVLIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPTPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL32_THEON
Sequence: MNEKARLLRIRARLKRKKPRFLRQEWWRYPKFKNDPKWRRPKGIDSKMRLKKKGKARSPSIGWSSPRLVRGLHPSGYEEVLVHNVKELEAIDPARQAARIARTVGARKREMILARAKELGVKVLNP
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: TF2H5_HUMAN
Sequence: MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLTQK
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.  Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.
What are the official names of this protein?
General transcription factor IIH subunit 5, General transcription factor IIH polypeptide 5, TFB5 ortholog, TFIIH basal transcription factor complex TTD-A subunit, TFIIH subunit p8.
What is the protein family that this protein belongs to?
Belongs to the TFB5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EFTS_ACTP2
Sequence: MAEITASLVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILARIGAGFGVLVEMNCETDFVAKDAGFLGLANEVADFALANKGTTIETLAAQFEEKRAALVAKIGENMNIRRVQYLDGQVIAQYLHGAKIGVLVAGEGSDEELKKVAMHVAASRPEFVNPEDVSAEVVAHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSQSVGDYLKSVNTKVTNFIRLEVGEGIEKVEEDFAAEVAKITGGNA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS1_METAC
Sequence: MDFEASARDLTTPVKGAKIVPNMSVDELVREYAGCAFGAGRLAEAVDIYYEMLASEKTTKFFGLAGAMTPAGMRGIIADLIRDGHIDVLVTTGANMVHDTVEALGLHHYKGSDCANDIQLRHECIDRIYDVYLPDQHFTDLEEFLQSVYAGLPQEKLSIRQVLTEIGKNLDDDSSILKTAAEMGVPVYCPALQDSVIGLQAWLYKEGNLLHVDAFADMHEFMEICYEAESAGAMLLGGGVPKNYILQSMLVTPKSFDYAIQLTMDRPETGGLSGATLDEAQSWGKVGEDAKSVTVYADATITLPLIVSAVRTRLSKR
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase 1, DHS 1.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: RL14_DESVV
Sequence: MIQVESTLQVADNSGAKKVACIKVLGGSHRRYATVGDIIMVSVKEAMPHCKVKKGDVMQAVIVRTAKEVRRADGSYIKFDSNAAVLLNKQGEPVGTRIFGPVARELRARNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PUR7_LACCB
Sequence: MNKTTLLYTGKAKQVYATDDPDVLWMAYTNQATALNGEKKAQIAHKGELNRAISTLLFKELTAVGIPTHYLDSPDSTTMIVKKAAMLPLEVVVRNYASGHFVTKFNVKPMMKLDPPIHEYYYKSDELGDPFMNEAQIFALHEATPEQLKQVRALTDRINTYLMQRFAAIGITLVDFKLEYGTLKDGTLVLADELSPDNFRLVDQQTGASLDKDVFRQNRGPLTPVYEEVLSRLQEKGAAHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: IGS1_PETHY
Sequence: MTTGKGKILILGATGYLGKYMVKASISLGHPTYAYVMPLKKNSDDSKLQLLKEFESLGVTIFYGELSEHDKLVAVFKEVDIVISTLAVPQYLEQLKVIEAIKEAGNIKRFVPSEFGNEVDRVRALPRFQAVLDNKKKIRRATEAAGIPFTFVSANSLTAYFVDYLLHPRQKSEQVTIYGSGDAKAVLNYEEDVAAYTIKAADDPRAANRVLIIKPPKNIVSQLDLVSSWEKTTGSTLKMTHISEQEIIKLSESINFPENIHASILHNIFIAGAQLSFELTQDHDLEASELYPNYNYTSVDEYLKICLVNPPKPKLATYAQPST
What is the function of this protein?
Involved in the biosynthesis of the floral volatile isoeugenol (PubMed:16782809, PubMed:17241449, PubMed:19222805).  Catalyzes the synthesis of the phenylpropene isoeugenol from coniferyl acetate (PubMed:16782809, PubMed:17241449, PubMed:19222805).  Phenylpropenes are the primary constituents of various essential plant oils (PubMed:16782809).  They are produced as antimicrobial and antianimal compounds, or as floral attractants of pollinators (PubMed:16782809).  Isoeugenol is a characteristic aromatic constituent of spices and a floral volatile compound (PubMed:16782809).
What are the official names of this protein?
Isoeugenol synthase 1, PhIGS1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: PRMC_SHEON
Sequence: MADQSCIAEALQWAYVQLAASSESAHLDAEVLLLYCLNKNRAYLYTWPEKALSVEQWKRFQQMVQRRQQGVPVAHIVGEREFWSLPFIVNDTTLIPRPDTEILVESALNLPLESNAKVLDLGTGTGAIALALASERAAWQITAVDKVEDAVALAKANRTNLKLEQVEILQSDWFSAVTSHDFDLIVSNPPYIDEADEHLHQGDVRFEPQSALTAADEGFADLYYIAKTARDYLKPNGYILLEHGFEQAVKLRAKLIELGYQNVATVRDFGSNDRCTMGKWMGLIGI
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: IELA_ASPFC
Sequence: MKFSLACLLALAGLQAALADPATCEKEAQFVKQELIGQPYTDAVANALQSNPIRVLHPGDMITMEYIASRLNIQVNENNEIISAHCA
What is the function of this protein?
Elastase inhibitor.
What are the official names of this protein?
Elastase inhibitor AFLEI.
Protein: UGDH3_ORYSJ
Sequence: MVKICCIGAGYVGGPTMAVIALKCPAIEVVVVDISKPRIDAWNSEQLPIYEPGLDEVVKECRGRNLFFSTDVEKHVAEADIIFVSVNTPTKTRGLGAGKAADLTYWESAARMIADVSKSDKIVVEKSTVPVKTAEAIEKILTHNSKGINYQILSNPEFLAEGTAIDDLFKPDRVLIGGRETAEGRKAVQALKSVYAHWVPEDRIITTNLWSAELSKLAANAFLAQRISSVNAISALCEATGANVTEVAYAVGKDSRIGPKFLNASVGFGGSCFQKDILNLVYICECNGLPEVANYWKQVIKINDYQKSRFVNRVVSSMFNTVSGKKIAVLGFAFKKDTGDTRETPAIDVCHGLLGDKAQISIYDPQVTEDQIQRDLAMGKFDWDHPMHLQPTSPTAFKQVSVVWDAYEATKNAHGLCILTEWDEFKTLDYQKIYDNMQKPAFVFDGRNVVDPEKLREIGFIVYSIGKPLDAWLKDMPAVA
What is the function of this protein?
Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase 3, UDP-Glc dehydrogenase 3, UDP-GlcDH 3, UDPGDH 3, Os-UGD3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: PROB_ACIBT
Sequence: MIEVVDGQRKLSECKRIVVKIGSSLLTANGQGLDLDAISHWAKQIADLHNAGHEIILVSSGAVAEGMVRMKLASRPTDLPSLQACAAIGQMGLIHTWSSVLENHSIRTAQVLLTHDDLADRRRYLNSCDALQNLIDWRVIPVINENDTVSTDEIRFGDNDTLAAMVAGQVHADLLIILTDQQGMFDSDPRHNPDAKLLSTVRAMDDVLFEMAGGGGVLGRGGMVTKVRAARLAAKSGCPTLIASGESDNVLSRVMAGEMLGTLFTTDKDRMTAHQQWLAAHLQTAGRLVIDDGAVEAIKLKHRSLLPVGVKTVEGHFDRGDVVECVDKQGKRVAVGRVNFSSRSAEIIKGLSSDKVYQVLGEARSLEMIHRDHMAIY
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_COXBN
Sequence: MKEYLNFLQFILDHGVAKTDRTGIGTKSVFGYEMRFNLREGFPLVTTKKIHLKSVIYELLWFLRGDTNIQFLNDNGVTIWDEWADENGDLGPIYGKQWRRWHCPDGRTVDQMQRLIREIKTNPDSRRLIVSAWNVGELDQMALPPCHLLFQFYVADGFLSCKLTQRSADAFLGVPFNIASYSLLTHLIARQCNLKAGEFIWSGGDCHIYNTHQDQVSTQLSREPRALPQLIINRDPSSLYDYNFNDFSIVNYHPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_YERPG
Sequence: MSKSENLYAQAQQLIPGGVNSPVRAFTGVGGIPLFIERADGAYLFDVDGKAYIDYVGSWGPMILGHNHPAIRQAVIEAVERGLSFGAPTEMEVKMAQLVTDLVPTMDMVRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPTDFAKHTLTCTYNDLASVRQAFEQYPQEVACIIVEPVAGNMNCIPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYHVIPDLTCLGKIIGGGMPVGAFGGRREVMNALAPTGPVYQAGTLSGNPIAMAAGFACLTEISQVGVYETLTELTDSLATGLRHAAKEENIPLVVNHVGGMFGLFFTNADTVTCYQDVMNCDVERFKRFFHLMLEEGVYLAPSAFEAGFMSLAHSNEDIQKTVNAARRCFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_PSEPW
Sequence: MTENNPTRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGDVQAIYVDTPGMHKANDKALNRYMNRNASAALKDVDVVIFVVDRTRWTDEDQLVLERVQYVTGPLIIAVNKTDRMDEKAELIPHLQWLQEQLPNAEVVPISAQQGHNLEALEALIAKHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGHVLHIHALILVERDGQKKIIIGDKGERIKRIGSDARKDMETLFDAKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RLMKL_HAEIE
Sequence: MKQLFATTSRGFEELLKVELTELGAQEAKVVQGGVHYQADDETLYRTLLWSRLASRILFPLIETKIYSDLDLYAAVSGFNWLAQFDERVTFFVDFNGTNQEIRHTQFGAMRVKDGIVDYFERQGKTRPDVDKIQPDVRIHAYLNRENLVISLDLSGEALHLRGYREDAGQAPLRETLAAAIVMRSGWQVGSPLVDPMCGSGTLLIEAAQIEAKIAPQLYRLHWGFDFWKAHNQSAWEKVKNEAIELAEEKQSEIQPHFYGFDLDHRVLKKAQKNAQNGGVSHLIKWQQADVAALKNPRLNEVGTVICNPPYGERLGTTPALIALYSVFGQRLKKEFCGWNVSVFSSESTLLDCLRMRASRQFKAKNGPLDCVQKNYQVSERKSDAITDEKELEFNRTSEVAPDFANRLQKNIKKISKWAKQQELDAYRLYDADLPEYNLAVDRYADYIVVQEYAAPKNIDENKARQRLLDAVTATLQVTGVETNKLILKVRQKQKGTNQYEKLANKGEYFYVNEYGAQLWVNLTDYLDTGLFLDHRLTRKMIGELAKGKDFLNLFAYTGSATVHAALGGAKSTTTVDMSNTYLNWAEQNLILNDIEGKQHKLIQADCLQWLEKCDRQFDLIFVDPPTFSNSKRMEESWDVQRDHVKLMSNLKRVLSNNGTIVFSNNKRGFKMNLVALEELGLSAIEISHKTLPLDFERNKQIHNCWMIQHI
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_STAAT
Sequence: METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CHLAD
Sequence: MAHKKGVGSSRNGRDSNPKMRGVKRFGGELVRAGNIIVRQCGTKIKPGANVGVGRDWTLYALVDGVVQFSHYSRTQKKVSVIPVAAETTAN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RR7_ILLOL
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SATT_MOUSE
Sequence: MEKSGETNGYLDGTQAEPAAGPRTPETAMGKSQRCASFFRRHALVLLTVSGVLVGAGMGAALRGLQLTRTQITYLAFPGEMLLRMLRMIILPLVVCSLVSGAASLDASSLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGAGAQTLQSSSLGLENSGPPPVSKETVDSFLDLLRNLFPSNLVVAAFTTSATDYTVVTHNTSSGNVTKEKIPVVTDVEGMNILGLVLFALVLGVALKKLGPEGEDLIRFFNSFNEATMVLVSWIMWYVPIGIMFLIGSKIVEMKDIVMLVTSLGKYIFASMLGHVIHGGIVLPLVYFAFTRKNPFTFLLGLLTPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVDLNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLSLILAVDWIVDRTTTVVNVEGDALGAGILNHLNQKVVKKGEQELQEVKVEAIPNSKSEEETSPLVTHQNPAGPVAIAPELESKESVL
What is the function of this protein?
Sodium-dependent neutral amino-acid transporter that mediates transport of alanine, serine, cysteine, proline, hydroxyproline and threonine.
What are the official names of this protein?
Neutral amino acid transporter A, Alanine/serine/cysteine/threonine transporter 1, ASCT-1, Solute carrier family 1 member 4.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: ATPB_SHESH
Sequence: MSTGTVVQVIGAVVDVEFPHDAVPQVYDALEIKSEGLVLEVQQQLGGGVVRTIAMGSSDGLRRGLEVVNSGSPITVPVGEKTLGRIMNVLGEPVDEAGPIGEEDRYVIHREAPSYEDQSSSTELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYYEMEDSGVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGKDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRNIASLGIYPAVDPLDSTSRQLDPQVVGQEHYDVATGVQTQLQRYKELKDIIAILGMDELSDDDKTTVFRARKIEKYLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGILDGEFDHLPEQAFYMVGSIDEAVEKANKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SERC_SHEHH
Sequence: MSAIFNFCAGPAMLPPAVMQKAQKELLNWNGQGVSVMEVSHRSKEFIALTEQAEADLRQLMDIPFNYHVLFMHGGGRGQFSAVVNNFLGNDGKALYLVDGSWSKAAVEEAEKLAGKDKIDTIDIVSTVQGKREVSIPDLTQIDKDYRYLHYCPNETVDGIEIFESINSPWPVIADMSSNILSRKIDVSQFGLIYAGAQKNIGPSGLSIVIVRDDMLVLPSLPQSSIMDYRLAVENDSMYNTPPTFAWYLAAEVFSWLKSVGGVCEMEKLNLEKAKRLYQCIDELDFYVSGVAKQNRSRMNVTFQLTNSELNSQFLEEAQVAGLVALKGHRSVGGMRASIYNAMPLEGVDTLVEFMQAFAAKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BORBU
Sequence: MARAKNGTVHVARRKRILKKTKGFWGTKKSNYKKAKDTLXKGMMYATRDRKVRKRDFRRLWISRISAALSDTGVTYSRFIEGLLKSNIKINRKILSNLAIEDVEAFKKIVLEIRR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.