PharMolix/UniProtQA huggingface dataset:
Protein: RL29_CERS5
Sequence: MNAQELRSKTPDQLRDQLVALKKEAFNLRFQQATGQLENTARMRAVRRDVARIKTVLNEMAASAAAN
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RK1_PEA
Sequence: IPLFLHLLLMSRKLLMKRRTKVVRRMNLMLLLTLLLSPLSLRQGKLHWRLKSDRVRSKRFLEIQKLRELKKEYDLKTAISLVKETAKTKFVETVEAHFRLNIDPKYNDQQLRATVSLPKGTGKPIKVAVLTQGERFDEAKNAGADLVGGEDLIEQIKGGFMEFDKLIASPDMMPKVASLGKILGPRGLMPNPKAGTVTANIPQAIAEF
What is the function of this protein?
This protein binds directly to 23S ribosomal RNA.
What are the official names of this protein?
50S ribosomal protein L1, chloroplastic, CL1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADD_FLAPJ
Sequence: MKIGLYFGTFNPIHIGHLIIANHMAENSDLDQVWMVVTPHNPLKKKDTLLDDYQRLHLVNLATEDYPKLKPSDIEFKLPQPNYTVNTLAHLQDKFPSYEFSLIMGEDNLNSLHKWKNYEAILQNHQIYVYPRLNTDTIDNQFINHQKIHIIKAPIVEISSTFIRENIKNKKNIQPLLPPKVWKYIDHSNFYKK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: FLA14_ARATH
Sequence: MSSSLTIFFFFFASTFLYTSSNSFNITNILNEHDDFSNFNQLLSETQLASTINKRQTITVLVVSNGALSSLSGQPTSVIKKILSLHIVLDYYDQKKLKNLSKKTVLLTTLFQSSGLARGQQGFLNATVMKNGDVAFGSAVPGSSLDAQLQDTVAALPFNISVLHISSAIMIDVKGDNAPTASPLSPVSSPPRPAESPNDDGQDFDEPPSSAPGAAADEPSENAGSANGVSRNDSQPAFAFTLLMSFIWWFMARLR
What is the function of this protein?
May be a cell surface adhesion protein.
What are the official names of this protein?
Fasciclin-like arabinogalactan protein 14.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: UPL6_ARATH
Sequence: MFFSGDPSTRKRVDLGGRSTKERDARKLLEQTRMERNRRLLQKQQNSAALKIQKFFRGRRSMAIERSKVRHDFCETYGNNCQNVDRHCFEPGSSFLRQFLFFFKAQNSGDFVILVETCRLLQSFVDSSGDIVSLFSGLDYSSEHNLVDFRVKKLAFTCIEAIHQNRNRLRDQLLVTPEEASISTAILMEAVSLLLDPKLPWVCKIVSYLQKRKVFKLVREMVTTAKESPRGKTMTGNILSLERVLILIVPHIGREPCCCTVVDPRWSFSSMILTIPLIWKLFPNLKVVFANPSLSQHYIHQMASCIQKDTCVLPMETSPEFPGYACLLGNTLDTANVVLSQPECSLDMAIDIALVATFFLETLPPVKSSEGESRQGSSDEDDMLIDDVPGLVLNKALEQQITNAIDSRFLLQLTNVLFRQVSLGMQSYDEDKEALAIGTASSFLYAAFNTLPLERIMTILAYRTELVAVLWNYMKRCHENQKWSSMPKLLAYLPGDAPGWLLPLVVFCPVYKHMLMIVDNEEFYEREKPLSLQDIRLLIIILKQALWQLLWVNPLTQPNTGKSVSNDLSKKNPIELIQNRMGIVVSELLSQLQDWNNRKQFTSSSDFQADSVNEYFISQAIMEGTRANYILMQAPFLIPFTSRVKIFTTQLATARQSHGSQGIFARNRFRIRRDHILEDAYNQMSALSEDDLRSSIRVTFVNELGVEEAGIDGGGIFKDFMEKITRAAFDVQYGLFKETADHMLYPNPGSGMIHEQHLQFFHFLGSLLAKAMFEGILVDIPFATFFLSKLKQKYNYLNDLPSLDPELYRHLIFLKRYKGDISDLELYFVILNNEYGERTEEELLPGGQDMRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIPKEWIDMFNEHELQVLISGSVDSLDIDDLRNNTNYAGGYHAGHYVIDMFWEVMKSFSTENQKKFLKFVTGCSRGPLLGFKYLEPAFCIQRAAGSASNESVDRLPTSATCMNLLKLPPYQSKELLETKLMYAISAEAGFDLS
What is the function of this protein?
Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
E3 ubiquitin-protein ligase UPL6, Ubiquitin-protein ligase 6, HECT-type E3 ubiquitin transferase UPL6.
What is the protein family that this protein belongs to?
Belongs to the UPL family.
Protein: MURQ_BACAA
Sequence: MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MEP1_ARTOC
Sequence: MHGLLLAAGLISLPLHVLAHPQPSSTSLAGRAVDLNEYRIGHRSSYTSNDEMMKQPSIASFRAGTYVEVATEMVKQTMPNMEFRLVDDHYIGQSGIGHVRFRQTMHGIDIDNSDFNVNAYDNFYQIGQDGKVLSHGNSFYTGPAPESSPVQKRDFSDPMQALHGVRKALNLPIKAEGATVENMSEHKVMFKGTSGALSDPTAKLCYMAKEDGSLALTWRVETDIGDNWLLSYMDAKDTGKVHNVVDYVAHATFQVYKWGLADPTEGNREILTNPWNLQTSPLTWLADGQNNFTATRGNNAIAQYNPDGGNDYENNYRPSPKNLKFEYPYSANMDPPKTYIDASVTQLFYTSNVCHDLYYMLGFNEKAGNFQVNNRGQGGKGNDYVILNAQDGSGTNNANFATPPDGQPGRMRAYIWTRANPPRDASFEAGTIIHEYTHGLSNRLCGGPANSRCLNAIESGGMGEGWGDFYATAVRLKPKDTRKTNYVKGGWVNNSPKGVRMYPYSTDMSVNPLVYTSNNQLNEVHAIGTVWATMLYELLWNLIDKHGKNDGPVPIFKNGIPSDGKYLAMKIVMDGMAIQPCNPNFVQARDAILDADKNLTKASNKCEIWKAFAKRGLGVGAKFDPKNRIGSNEVPKECK
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 1, Fungalysin MEP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CP2DG_CAVPO
Sequence: MGLLTGDALFSVAVAVAIFLLLVDLMHRRQRWAARYPPGPVPVPGLGNLLQVDFENMAYSCDKLRHQFGDVFSLQFVWTPVVVVNGLLAVREALVNNSTDTSDRPTLPTNALLGFGPKAQGVIGAYYGPAWREQRRFSVSSLRNFGLGKKSLEQWVTEEAACLCAAFTNHAGQPFCPKALLNKAVCNVISSLIYARRFDYDDPMVLRLLEFLEETLRENSSLKIQVLNSIPLLLRIPCVAAKVLSAQRSFIALNDKLLAEHNTGWAPDQPPRDLTDAFLTEMHKAQGNSESSFNDENLRLLVSDLFGAGMVTTSVTLSWALLLMILHPDVQRHVQEEIDEVIGQVRCPEMADQAHMPFTNAVIHEVQRFADIVPMGVPHMTSRDTEVQGFLIPKGTMLFTNLSSVLKDETVWEKPLHFHPGHFLDAEGRFVKREAFMPFSAGPRICLGEPLARMELFLFFTSLLQRFSFSVPEGQPRPSDRGAPYLVVLPSPYQLCAVLR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2D16, CYPIID16.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RSMH_MYCBO
Sequence: MQTRAPWSLPEATLAYFPNARFVSSDRDLGAGAAPGIAASRSTACQTWGGITVADPGSGPTGFGHVPVLAQRCFELLTPALTRYYPDGSQAVLLDATIGAGGHAERFLEGLPGLRLIGLDRDPTALDVARSRLVRFADRLTLVHTRYDCLGAALAESGYAAVGSVDGILFDLGVSSMQLDRAERGFAYATDAPLDMRMDPTTPLTAADIVNTYDEAALADILRRYGEERFARRIAAGIVRRRAKTPFTSTAELVALLYQAIPAPARRVGGHPAKRTFQALRIAVNDELESLRTAVPAALDALAIGGRIAVLAYQSLEDRIVKRVFAEAVASATPAGLPVELPGHEPRFRSLTHGAERASVAEIERNPRSTPVRLRALQRVEHRAQSQQWATEKGDS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP1B_HUMAN
Sequence: MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Involved in regulation of ionic conductances and long-term synaptic plasticity.  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.  In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation.  May dephosphorylate CSNK1D and CSNK1E.  Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B, PPP1CD.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles.
Protein: IF3_NEIMA
Sequence: MIAQEREARINGEITAKEVRLISESGEQLGVVSVREALAMAEGQDVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDYQIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKMEGRQMVMMIAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCF2L_MOUSE
Sequence: MSDCWCFIFCKEHVRSNPLSPQHDGASREEADHQVDVSDGIRLVPDKAEATAATASDEIMHQDIVPLCAADIQEQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDEFKMKVPVMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSRWLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVKEDLQLALKEGNSILESLREPLAESAAHSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIENRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQDLLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPEALTKSPSPSPGSWRSSENSSSEGNALRRGPYRRAKSEMSEPRQGRTSSTGEEEESLAILRRHVMNELLDTERAYVEELLCVLEGYAAEMDNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRNIPAGLESCIDCPELVGRCFLERMEEFQIYEKYCQNKPRSESLWRQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYNAREEVYIIQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSHSLPLPTPSSTSPTKGNTRNVKKLEDRKTDPLSLEGYVSSSLPKPPEKGKGWSKTSHSLEAPEEDGGWSSAEELINSSDAEEDGGVGPKKLVPGKYTVVMDDEKGGPDTLAMRSGDMVEVVEEGAEGLWYVRDLTSSKEGWVPASSLSTLLGKSSSAQCLSSSGKIHCARQLCPEPAEILSPEPV
What is the function of this protein?
Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (PubMed:17000758, PubMed:11889037, PubMed:12006984).  Seems to lack activity with RAC1.  Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein.
What is the protein family that this protein belongs to?
Belongs to the MCF2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RHLB_SHIBS
Sequence: MSKTHLTEQKFSDFALHPKVVEVLEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_BURM9
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSIRRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3160_SYMTH
Sequence: MQIRYLGHSAFEITDGKWNLLIDPFITGNPACPVKAEELHPQYILVTHLHDDHVGDTVAIAKRTGATVITSFEGGQALAAQGVKVADMALGGKRRFDFGLVRVTLAFHGFGPTGGHACGFVIHIGGKRIYHAGDTALFSDMKLLNGVIEEPGIDVAMLPIGDNYTMGPEDAAVAVEWIRPKVVIPMHWGTFPVLVQDASGFAARVRETGASQPVVLRPGETYTL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase STH3160.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RL20_TREDE
Sequence: MSRSTSSDRRITRRKAILKQAKGFRGRRGTNFKAARDAVRKALLHSYVGRKDKKSDMRQIWITRINAAVRAEGITYSRFIAGMNKAGIQLNRKALSNMAIEDPTAFKAVVEASKKALGV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SYS_DICTD
Sequence: MIDIKILRENPEIMKENIILRNLDPQKYDVDYIIELDAKRRSLQKELDNLRAQRNKISQEIGKHQGEEREKLIKEAKILKEKIEELAKEYDNVEKELFSRLWQLPNFLSPKAPRGKDEKDNVEIKKWGEIKTFNFTPKDHLDLALLNDLVDFERGSKVTGSNFYYLKNEAVLLEFALFRLVIDTLLPEGFKLFITPDLARMEIIDGIGFQPRGPEAQIYRVEDTDLGLIATAEITLGGYHKDEILDELDLPLKYLGFSHCFRTEAGAYGRYNRGLYRVHQFSKAEIFIICRPEDSEEMHEYILGLEEKIFQKLEIPYRVLDICSGDLGAPAARKFDIEAWMPGRGEFGEVTSCSNCTDYQARRLNIRFRRVTGEVEYVHMLNGTAIAISRALIAIFENYQQEDGSILIPKALQPYIGISEIRPKK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTNB1_DANRE
Sequence: MATQSDLMELEMAMDPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEDDDVDNQVLYEWEQGFNQSFNQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDSAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTSGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDIHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMTWNETGDLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDAMGMDPMMEHEMAGHHPGPDYPVDGLPDLGHTQDLIDGLPPGDSNQLAWFDTDL
What is the function of this protein?
Key downstream component of the canonical Wnt signaling pathway (By similarity).  In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity).  In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity).  Plays a key role in dorsoventral patterning: in prospective ventral blastomeres, its down-regulation by axin1 and axin2 leads to inhibit the Wnt signaling pathway, while in prospective dorsal blastomeres, degradation of axin results in stabilization and nuclear translocation of ctnnb1 (PubMed:8562427, PubMed:30467143).
What are the official names of this protein?
Catenin beta-1, Beta-catenin.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Cytoplasmic when it is unstabilized (high level of phosphorylation). Translocates to the nucleus when it is stabilized (low level of phosphorylation). The majority of beta-catenin is localized to the cell membrane.
Protein: RS28_PYRHO
Sequence: MAEDEGYPAEVIEIIGRTGTTGDVTQVKVRILEGRDKGRVIRRNVRGPVRVGDILILRETEREAREIKSRR
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: YO161_YEAST
Sequence: MSYTRVDHPTGKMACHLRQILASPLFFANYVLHAAIHYPSSDIRGDIL
What are the official names of this protein?
Uncharacterized protein YOR161C-C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OBG_TRIL1
Sequence: MKFIDEVTLHCASGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDLIFEATKALSTLLELRHKQHQKAERGRHGMGKDRHGAAGEDLIVKVPVGTLIKDFETGEVLADLTEDGQRIILLKGGRGGQGNARFATATNKAPKFAQPGEEGEERKLRLELKLMADVGLLGLPNAGKSSLITKVSAARPKIADYPFTTLAPSLGVVGYKNYRSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGILVHLVDISGLPESDPYAAFEAINRELAMFSEELGQKAQIVGLTKMDLPTAQEHLTEAQAWFQERKIPVYPISSMTGEGVEALLDAIAERLWAAPREEW
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SALHS
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y676_TREPA
Sequence: MRCSHNWDDPPPLFGAVSYGMQEGAGRGVRREARDTPCRGTAEGLATSQPEDGETRAALQRIDHLDTQLLQLERDLAHYLEMAELPDPFSEN
What are the official names of this protein?
Uncharacterized protein TP_0676.
Protein: CHLL_SYNJA
Sequence: MEERAVKLAVYGKGGIGKSTTSCNLSVALAKRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLEAKGYHYEDIYPEDVIYRGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCVIVTDNGFDALFAANRIAASVREKAKTRKLRLAGLIGNRTSKRDLIDQYVSAVPMPVLEVLPLVEDIRISRVKGKTLFEMAETDPSLEPVCQYYLNIADELLARPEGIVPRPAEDRELFALLSDFYKTPVREPALV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RECA_MYCSS
Sequence: MAPQAPDREKALELALAQIEKSHGKGSVMRLGDEVRAPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGIAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDILVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITGALSNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRMDVRRIETLKDGTDAVGNRTRVKIVKNKVSPPFKQAEFDILYGKGISKEGSLIDMGVEHGFIRKSGSWFTYEGEQLGQGKENARKFLLENGDVANEIEKKIKEKLNIGAVVTADDVLPAPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_NOSS1
Sequence: MVSYASIPQSSDEAHSTVGASLQLDERKQDLNNFIQRHIGPSSADIQQMLDVLGFSSLDDLIEKTVPSAIRLHEQLQLPEAQTEYAALAKLKQIASKNQVFRSYIGMGYYDTITPSVIGRNILENPGWYTAYTPYQPEIAQGRLEALLNFQTMIIDLTGLEIANASLLDEATAAAEAMSMSYGVSKNKANAYFVSHDCHPQIIDVLQTRAKPLGIEIIIGDHQTFDFDKPIFGAVLQYPASDGTIYDYRAFIETSHAQGALVTVAADPLSLTLLTPPGEFGADIAVGSTQRFGIPLGFGGPHAAYFATKEEYKRQVPGRIVGVSKDVHGKTALRLALQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPEGLKQIAERIHHLTLVLGVWLQRLGYTITSQSFFDTLQIKLGEKPLQEILEAAEAYRINLRIVDTSTVGISLDETTTLEDVKDICRIFAGTDELPFVLNVQEFDWIIQQSSLKDEPFSRQSSYLTHPVFNRYHSETELLRYLHRLETKDLSLTTSMIPLGSCTMKLNATSEMIPVTWEEFGRIHPFAPLTQTRGYQILFQQLEAWLGEITGFAGVSLQPNAGSQGEYTGLLVIRQYHQSRGETHRNVCLIPNSAHGTNPASAVMCGMKVVAVACDAGGNIDIDDLKAKAEKHSHELAALMVTYPSTHGVFEAGIQEICAVIHSHGGQVYMDGANMNAQVGICRPGDIGADVCHLNLHKTFCIPHGGGGPGMGPIGVASHLVPFLPGHPVLESGKNPQNIGAVAAAPWGSASILVISWMYIVMMGADGLTQATKVAILNANYIAKKLAAYYPVLYKGQNGLVAHECILDLRALKKSANIEIDDIAKRLIDYGFHAPTVSWPVAGTIMVEPTESESQAELDRFCEALIAIRQEIADIEAGKVDIQDNSLKNAPHTVESLIVGEWPHPYSREQAAYPAPWTREHKFWPSVGRIDAAFGDRNFVCSCLPMDAYN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.