PharMolix/UniProtQA huggingface dataset:
Protein: DRL9_ARATH
Sequence: MAGELVSFAVNKLWDLLSHEYTLFQGVEDQVAELKSDLNLLKSFLKDADAKKHTSALVRYCVEEIKDIVYDAEDVLETFVQKEKLGTTSGIRKHIKRLTCIVPDRREIALYIGHVSKRITRVIRDMQSFGVQQMIVDDYMHPLRNREREIRRTFPKDNESGFVALEENVKKLVGYFVEEDNYQVVSITGMGGLGKTTLARQVFNHDMVTKKFDKLAWVSVSQDFTLKNVWQNILGDLKPKEEETKEEEKKILEMTEYTLQRELYQLLEMSKSLIVLDDIWKKEDWEVIKPIFPPTKGWKLLLTSRNESIVAPTNTKYFNFKPECLKTDDSWKLFQRIAFPINDASEFEIDEEMEKLGEKMIEHCGGLPLAIKVLGGMLAEKYTSHDWRRLSENIGSHLVGGRTNFNDDNNNSCNYVLSLSFEELPSYLKHCFLYLAHFPEDYEIKVENLSYYWAAEEIFQPRHYDGEIIRDVGDVYIEELVRRNMVISERDVKTSRFETCHLHDMMREVCLLKAKEENFLQITSNPPSTANFQSTVTSRRLVYQYPTTLHVEKDINNPKLRSLVVVTLGSWNMAGSSFTRLELLRVLDLVQAKLKGGKLASCIGKLIHLRYLSLEYAEVTHIPYSLGNLKLLIYLNLHISLSSRSNFVPNVLMGMQELRYLALPSLIERKTKLELSNLVKLETLENFSTKNSSLEDLRGMVRLRTLTIELIEETSLETLAASIGGLKYLEKLEIDDLGSKMRTKEAGIVFDFVHLKRLRLELYMPRLSKEQHFPSHLTTLYLQHCRLEEDPMPILEKLLQLKELELGHKSFSGKKMVCSSCGFPQLQKLSISGLKEWEDWKVEESSMPLLLTLNIFDCRKLKQLPDEHLPSHLTAISLKKCGLEDPIPTLERLVHLKELSLSELCGRIMVCTGGGFPQLHKLDLSELDGLEEWIVEDGSMPRLHTLEIRRCLKLKKLPNGFPQLQNLHLTEVEEWEEGMIVKQGSMPLLHTLYIWHCPKLPGEQHFPSHLTTVFLLGMYVEEDPMRILEKLLHLKNVSLFQSFSGKRMVCSGGGFPQLQKLSIREIEWEEWIVEQGSMPLLHTLYIGVCPNLKELPDGLRFIYSLKNLIVSKRWKKRLSEGGEDYYKVQHIPSVEFDD
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At1g58602.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: SPO13_SCHPO
Sequence: MMSNSQISKLFSSISNKENSNENALKESTNKQLNNANTLAITHLKEQLSREVQRREELEGLLEQSQKEMEDLSVSLFTEANEMVAKARQDTEVLKRELDYLRAKEKGRIGKLRSIQTAVRTSIEARKLLSYSNESNYH
What is the function of this protein?
Involved in sporulation.  Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation.
What are the official names of this protein?
Sporulation-specific protein 13.
Protein: LSPA_CHLMU
Sequence: MTTRSLSTFLTSFLLVSLDWVSKLVVLLKSCQLSPHSPALLYSYVWGHFSFLIVPSFNEGAAFGLFAQYKIPLLIFRVFVILCLFLFLGIKFRSLHIRTRIALTLILAGALGNVGDILFHGKVVDFLSINYYSWSFPSFNLADAFISLGTLLLVGHLYFSKEDKKYF
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROB_BACP2
Sequence: MKTLEVKTSSATYPVYIGDGIKRNIVDLMTSTGHSYTKLLIVTDTAVDAIYGDEMVRLLEQKWSVHKVVVPSGEQSKSFAEFEHIHTKAIQFQLDRSSCIIALGGGVIGDLAGFVAASYMRGIDFIQVPTTLLAHDSAVGGKTGINHPLGKNLIGAFHQPKAVIYDTSMLETLSQTEMRSGFAEVIKHALISSEDFLKELMSIRSLDECSKSELAHMLYQGIEVKASIVQKDEREQGVRAFLNLGHTLGHAIEAEYGYGVITHGDAIAIGMQFALYVSEKKLGLSLHRTELKEWMKKLGFPVQVTQDISTKTFVDRMIGDKKARGGTVQFVLLKQVGDAVLQSFTKDDLHQWLDEWKREEGCL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS10_METJA
Sequence: MGNCNEYTALKIGALLHDIGKFIQRASDKPKSKGHDKFGYEFLKEKFKNGFLNHLDEKTKDKILEIVKEHHNQKIKDDLIGIVRLADWLSSGERREPKGDPENVEVLNTEEQKLLSIFETVCIGELTENLYKNGFKYSLKPLNVSDAIFTDKPYPNENYKELFSKFEDEIKDFKGDVSFEELYQLMQKYTWCIPSVTMWKKAGSLKGGLPDVSLFDHSKTTCAIACCLYQMYVKENKKKNKYAKEYIDDKTLEKLFNNDNGWNKEIFSLIHGDLSGIQDFVFTITTKYATKSLKGRSFYLDFLTEYFAKYICKELNLPITNILFYGGGHFYILSYKVDENLINKLEKEINEVLFNMFRTKIYITIAEVGVTPNDFKKSEDKESKEKTWGFAKKWKEVSEKTVEKKLRRFEYKLEGLFEPYNRGSENRCVICRNEFDKNEKGYAIRENESKSERICDYCASFVALTDILKNFQMEKTIKFNKAYPIIHLTKNKDNLSLQREEFSFLTVKAIEKLESKFRVLSDENYFLKEYKLPHDSGELIIPYKIWAIAFPIIENETEKRILDFDGLAEKAFERTGTRKIGILKMDVDNLGEIFTTGLGNDATISRMSTLSSMLTLFFTGYIPHLIKNEEFEVNGKKYKFKDNIYLVYAGGDDTLIVGAWDAVWELAKRIRGDFKKFVCYNPYITLSAGIVFVNPKFEFKKAVNMAEEELENGKNYIIYEDEETEKKVDKNALTVFNCPMNWDLEVEYNEYCWTKLKSYLEGINKEMVELESLVKKFNEDDLEKNLKKQLKRQIRKESYI
What is the function of this protein?
When associated with the ternary Csm effector complex (the crRNA, Cas proteins and a cognate target ssRNA) synthesizes cyclic oligoadenylates (cOA) from ATP.  cOAs are second messengers that stimulate the ssRNase activity of Csx1, inducing an antiviral state important for defense against invading nucleic acids.
What are the official names of this protein?
CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ssDNase Cas10, Cyclic oligoadenylate synthase.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Cas10/Csm1 family.
Protein: MEN1_CANLF
Sequence: MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPTGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQTQGVQSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREAEAAEAEELWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGPGGGQGAMSGPPRKPPGTVPGTARGPEGGSTAPAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL
What is the function of this protein?
Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4).  Functions as a transcriptional regulator.  Binds to the TERT promoter and represses telomerase expression.  Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity.  Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA.  Positively regulates HOXC8 and HOXC6 gene expression.  May be involved in normal hematopoiesis through the activation of HOXA9 expression.  May be involved in DNA repair (By similarity).
What are the official names of this protein?
Menin.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUE_DROWI
Sequence: MILRLFILLSIITVYLQLSVGIQQQFEFAITLKSKILFVDEHWNVVNTAAHEFDELSALTFDESEERIYFNDGQHQNSSIFSLRKVGKSNHLAEQTIQRYGNESVGGIAYDPLNRTIYWSDLLQKKIFYASIDTVATEMPKILVDLSEENGTPYGVAIDICGRKLYWTNSNINHPTVERIDLNGTGRLAIIDKNIDSPRGIVVDQGAKRIFWIDDLKGIFFAVMSAQLDGSDVKLVLKDKNHEPQNLAVTRNAIYWTDRTTKSVWSHLKEPEIATTTTTTTTSTTQIPTVEGEEGTGAMDDNDIWPVGDFETTPKKSPLERKINLTEEARGIVARTGFYQLQKDSQCSKVIQLVKQRLDESQQNNRVLNVVDEQLDELQREHCLGGGTYYPQQKFCVCVPGYKGTRCETNECHNFCVHGTCQISEMGYPKCYCQPGYSGERCEVKKCLNFCQNGGDCQLDELTGEASCQCPSNFGGLRCEHNSTEICGLFCRLLKHDSNTSVPFGCHDICEQLAKDSSDLIAIPEYKHLDVCLAPNAWTGSVLMPLMISLILILLLLTIFIHGLRRLYKPKRPHIKKTFVVRKQARTNSSSDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEFAKSNCKDDKKILIHNMEDDLY
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PLSY_ECO27
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y706_METJA
Sequence: MRDAYLMMVLMDALKEIFDLKEILKSPIRNKKVILFVSLVFILSLVLLYILVVNIKYFSYLGDIIFQNFQKHVENLKITLNEDNLHIILAIWKNNLTVCILNYILGIFSLFVIAVNSYILSYVLYKFGAESFIYLVLPHGIIEIPALILSASGGVLFNMGLVNFLINIKFGTKREVLYYIKESLKLLILSIILFIVAGIVEGTITFKIAKIMFS
What are the official names of this protein?
Uncharacterized protein MJ0706.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_BACFR
Sequence: MASFVIEGGHRLSGEIHPQGAKNEVLQIICATLLTAEEVTVNNIPDILDVNNLIQLMRDMGVTVAKTGVDSYSFKAANVDLAYLESDNFLKKCSSLRGSVMLIGPMVARFGKAMISKPGGDKIGRRRLDTHFIGIQNLGADFTYNEEREIYEISAEELKGTSMLLDEASVTGTANIVMAAVLAKGKTTIYNAACEPYLQQLCKMLNRMGAKISGIASNLLTIEGVEELHGTDHTVLPDMIEVGSFIGMAAMTRSEITIKNVSYENLGIIPESFRRLGIKLEQRGDDIFVPAQDCYQIESFIDGSIMTIADAPWPGLTPDLLSVMLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRAVVIGHNHGFTLRGGNMTSPDIRAGIALLIAAMSAEGISRIHNIEQIDRGYQNIEGRLNAIGARITRI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX1B_HETMC
Sequence: ECRYLFGGCKTTADCCKHLGCRTDLYYCAWDGTF
What is the function of this protein?
Gating-modifier toxin that potently and selectively acts on Nav1. 1/SCN1A and Nav1. 3/SCN3A (PubMed:32335140).  It enhances hNav1. 1/SCN1A currents and delays fast inactivation of the channel (EC(50)=11. 6 nM), leading to a sustained current (PubMed:32335140).  Similar effects are observed at Nav1. 3/SCN3A (EC(50)=11. 8 nM), but with less sustained currents (PubMed:32335140).  When tested on Nav1. 2/SCN2A, the native toxin decreases the peak current by 50% at saturating concentration, whereas the recombinant toxin only shows a weak decrease of peak current (PubMed:32335140).  The native toxin specifically activates the voltage-gated sodium channel Nav1. 1/SCN1A in somatosensory neurons to elicit acute pain and mechanical allodynia (PubMed:27281198).  When tested on Nav1. 1/SCN1A, the toxin induces a hyperpolarising shift of the voltage-dependence of steady-state activation, and induces a depolarizing shift in the voltage dependence of inactivation (PubMed:32335140).  In addition, it does not modify the recovery from fast inactivation in Nav1. 1/SCN1A (PubMed:32335140).  The toxin hydrophobic face probably interacts with the domain IV voltage-sensor of Nav1. 1/SCN1A and Nav1. 3/SCN3A and may trap the voltage-sensing S4 helix in a partially activated state (PubMed:32335140).  In vivo, intracerebroventricular injection into mice elicits convulsions, spasms, tremors and rapid death (By similarity).  When injected into mouse hindpaw, the toxin elicits an immediate and robust response to pain (PubMed:27281198).  However, intraplantar injection of toxin does not cause neurogenic inflammation or alter sensitivity to heat, indicative of a modality-specific effect on mechanosensitive neurons (PubMed:27281198).
What are the official names of this protein?
Delta-theraphotoxin-Hm1b, Delta-TRTX-Hm1b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 09 (HaTx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNP2_THESM
Sequence: MRRKPKTLPPTLRDKNRYIAFQVTGERPFKKEMIKKAIWDVSLKTLGELGTARAKPWFIKFDEKTQTGIVRCDRKYVEEIRFVLTLITEINGSKAIVRTLGVSGTIKRLKMKFLKEFGWK
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_POLSJ
Sequence: MSAIVDIVGREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGSREAIELRDGDKSRYLGKGVLKAVEHINTEISEAVLGLDASEQAFLDRTLIDLDGTDNKSRLGANATLAVSMAVARAAAEEAGLPLYRYFGGSGAMQMPVPMMNVVNGGAHANNNLDLQELMIIPIGAPSFREAVRYGAEVFHALKKILHDKGMSVAVGDEGGFAPNVPSHEAAIQMILEAIDKAGYVAGEQIALGLDCAASEFYKDGKYVLAGEGLSLDATEWTNILATWVDKYPIISIEDGMAEGDWDGWKILTERLGKQVQLVGDDLFVTNTKILKEGIDKHIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGTNAGQIKTGSLSRSDRMAKYNQLLRIEEDLGDIATYPGRAAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RAB23_MOUSE
Sequence: MLEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQQITEDPEQTHSSSNKIGVFNASVGSHLGQNSSSLNGGDVINLRPNKQRTKRTRNPFSSCSVP
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S. aureus, by promoting their capture by autophagosomes that then merge with lysosomes (By similarity).  Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity.  Regulates GLI1 in differentiating chondrocytes.  Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity.
What are the official names of this protein?
Ras-related protein Rab-23, Protein open brain, Rab-15.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Endosome membrane. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or Mycobacterium.
Protein: RL10_BEUC1
Sequence: MARPDKAAAVAELTEKFRSSSAAVLTEYRGLTVAQLKALRTSLGGSAHYAVVKNTLTAIAAKEAGIDAFEGQLSGPTAIAFVEGDPVAAAKGLRDFAKANPALVIKAGVLDGKAITSSEITALADLESREVLLAKAAGAFKAKLYQAAYLFTAPASQAVRTIDALREKQADAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: IXTPA_SULNB
Sequence: MKIVLATGNKGKLREFRQMCQDEVLPFSDLLGMFEIVEDGDTFAANALIKARTIYNKLKEKHPEEAYVVIADDSGISVPALGGIPGIYSARYAGEGASDKENLYKLIDTLKEKDFKSTPAYYTAAIAIVSDLGEYVVHGWMHGNVIDEARGDKGFGYDPMFIPAGFDKTLGEMDDGVKTAISHRGKALSLAKPIIQMLKNKEKNASDLK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: TMOD3_HUMAN
Sequence: MALPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDREDYVPYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEALTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVFDEPPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTAVELEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRVEGDHQ
What is the function of this protein?
Blocks the elongation and depolymerization of the actin filaments at the pointed end.  The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
What are the official names of this protein?
Tropomodulin-3, Ubiquitous tropomodulin, U-Tmod.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PDM2_DROVI
Sequence: CGKSYEEEEEEEDDELEADVAQNLSSKRSARQLDADMENEVLNLARSVSPAAKRLALEHTAEPALAAQSAAAATPPVGLSLPPTAPLGFGPEDMQQALQLQLHSYIEMVRQLAPDAFPNPNLATQFLLQNSLQALAQFQALQQLKQQRDQQLPTASEQLPTRHYSTPLSKSPLRSPSLSPVARSMEPQQAQRTPPNSLAAAGLGLSSAVLTPNTPSMQQQQQQTMTSTTNASSTPKPLASGATVAAVMATKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSSVAKSAGGVFNINTMTTNLSSTPESILGRRRKKRTSIETTIRGALEQAFVLNCKPTSEEINQLSERLHMDKEVVRVWFCNRRQKEKRINPSLDLDSPTGTPLSSHAFGYPPQALNMSNGGHVLLEAGGSHCGSSISSGE
What is the function of this protein?
DNA-binding regulatory protein implicated in early development.  Involved in neuronal cell fate decision.  May act as an octamer-dependent activator of transcription (By similarity).
What are the official names of this protein?
POU domain protein 2, Miti-mere, Pdm-2, Protein didymous, dOct2, dPOU-28.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYTA2_DICDI
Sequence: MTKVGGLGATHQADKTVEDIVNAVKPSIQSKLGTNISNLKVISYKTQLVNGTNYFVKVRTENGYAHLRIYKPFSGAASLVSVQDGKAKDDEITYF
What is the function of this protein?
Intracellular thiol proteinase inhibitor.  Inhibits cathepsin B, but not papain.
What are the official names of this protein?
Cystatin-A2.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
Protein: UNG_COXB2
Sequence: MTTMAETQTWQTVLGEEKQEPYFQEILDFVKKERKAGKIIYPPQKDIFNALKLTPYEAVKVVILGQDPYHGPNQAHGLAFSVRPGVPAPPSLQNIFKELHADLGVSIPSHGFLEKWAKQGVLLLNAALTVEAGKPQSHANIEWHRFTDKVIESLNDHPEGIVFLLWGSYAQKKSQLITNLRHRILKAPHPSPLSAARGFLGCRHFSKANQLLHEMGRGEIDWALDEKVS
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_ESCF3
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: YGHT_ECOLI
Sequence: MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQAGNVGRAVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQDQIPGAYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEKAITDFMTARGYH
What are the official names of this protein?
Uncharacterized ATP-binding protein YghT.
What is the protein family that this protein belongs to?
To E.coli YghR and YghS.
Protein: GPPA_ECO8A
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: GLPK_RHOCS
Sequence: MGERPCILAIDQGTTSSRAIVFDAAASVLAVAQTEFPQHYPADGWVEHDPEDIWRSTLEVSRQALQAAEAKGARVVAIGVTNQRETTLIWDRRTGRPIHNAIVWQDRRTAADCAALAADGNETMVQARSGLLLDPYFSATKAAWLLDHVSGARMRAENGHLAFGTVDSFLLWRLTGGRVHATDATNASRTNLFNIHTQDWDPELLRLFRVPAALLPEVKDSADSFGQTDPALFGRPLPVLGLVGDQQGATIGQCCFEPGTIKSTYGTGCFVVVNTGATPVPSRHRLLTTIAYRIDGRTDYALEGSIFIAGAAVQWLRDGLGIVRTAAETEALAAGLPDNGGVYMVPAFTGLGAPHWDAAARGTLTGLTRASGRAHLARAALEASCYQTCDLLAAMREDGATPAALRVDGGMVANGWMVQFLADLLDLPVDRPVVMETTALGAAYLAGRKAGLYGDFAEFTRVWRRDRRFDPAMPTSTRTALLAGWQDAVRRTRSGAPD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL5_MYCA1
Sequence: MTTTEKVQPRLKERYRNEIRDSLQQQFGYANVMQIPTVTKVVVNMGIGEAARDAKLINGAVNDLALITGQRPEIRRARKSIAQFKLREGMPIGARVTLRGDRMWEFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQSVFHEIDVDKIDRVRGMDINVVTSATTDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.