PharMolix/UniProtQA huggingface dataset:
Protein: P2A12_ARATH
Sequence: MGVAHSDLHNDLSSSSCFGDRNILKPGLGDLPEACVAIIVENLDPVEICRFSKLNRAFRGASWADCVWESKLPQNYRDVLEKILGGFPENLQKRHLYAFLSRINSFDDATKKVWIDKRTSGVCLSISAKGLSITGIDDRRYWSHIPTDESRFSSVAYLQQIWWFEVDGEIDFPFPVGTYSIFFRLQLGRSGKWFGRRVCNTEQVHGWDIKPVRFQLWTEDGQYSSSQCMLTERGNWIHYHAGDVVVRESNRSSTKIKFSMTQIDCTHTKGGLSLDSVVVYPSSCKDQLKRF
What are the official names of this protein?
F-box protein PP2-A12, Protein PHLOEM PROTEIN 2-LIKE A12, AtPP2-A12.
Protein: SSEL_SALCH
Sequence: MNICVNSLYRLSTPQFHSLYSEDVSDEVLALLIGEVENGNQNCIDLLCNLALRNDDLGHKVEKLLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKNNTEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARMLSSDELAAATQGLVQESPFLSVNYPIGLIHPTTKENILSTQLLEKMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYYDLNENTKQEIIEAAKIAGISESDEVNFIEMNLQNNVPNGCSLFCYHTIQLLSNAGQNDPVTTLREFAEKFLTLSVEEQALFNTQTRRQIYEYSLQ
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity).
What are the official names of this protein?
Deubiquitinase SseL, Deubiquitinating enzyme, DUB, Deubiquitinating protease, Salmonella secreted effector L.
What is the protein family that this protein belongs to?
Belongs to the peptidase C79 family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. In phagocytic cells localizes to the Salmonella-containing vacuole (SCV). In epithelial cells localizes to the Salmonella-containing vacuole (SCV) and to the Salmonella-induced filaments (Sifs), which are tubular membrane extensions from the SCV that are formed at late stages of infection (By similarity).
Protein: IHFB_SHEHH
Sequence: MTKSELIEKLATRQSQLSAKEVEAAIKEMLEQMADTLEAGDRIEIRGFGSFSLHYRAPRTGRNPKTGTSVELEGKYVPHFKPGKELRERVDAINT
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TPIS_EHRCR
Sequence: MSLLIVANWKMYGDFLTFSSFTKELSANLVNVKADVEVVLCPPFIACSKIVDCAPNIKLGAQNCFYESEGKYTGEVSAKMLYSCGCSYVIVGHYERRSIFYESDYCVQLKAKSAIDAGLIPIICIGETLLDRENGMLKNALLDQCYNSFPKHGEFVIAYEPVWAIGSNTIPSIDMITESLDIIRSYDSKSNIIYGGAVNQSNIKDVIAINQLSGVLVGSASLKVSSFCDIIYGAVNVRQN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_XYLFT
Sequence: MSKVSGGGPCSRRRDGVDPALRSRARRRALQAVYAWQISGGVAKQVIAHFAHEQAYEVADLVYFEDLVEGVLTHCAELDEKLTPYLDRTIEEVDAIERAVLRLGAYELLYRQDVPYRVVINEAIMTAKRFGSKYGHTYVNGVLDRAALALRKVEVLG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SYS_ECO7I
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHGA_ACICA
Sequence: MNQPTSRSGLTTFTVIIIGLLALFLLIGGIWLATLGGSIYYIIAGVLLLIVAWQLYKRASTALWFYAALMLGTIIWSVWEVGTDFWALAPRLDILGILGLWLLVPAVTRGINNLGSSKVALSSTLAIAIVLMVYSIFNDPQEINGEIKTPQPETAQAVPGVAESDWPAYGRTQAGVRYSPLKQINDQNVKDLKVAWTLRTGDLKTDNDSGETTNQVTPIKIGNNMFICTAHQQLIAIDPATGKEKWRFDPKLKTDKSFQHLTCRGVMYYDANNTTEFATSLQSKKSSSTQCPRKVFVPVNDGRLVAVNADTGKACTDFGQNGQVNLQEFMPYAYPGGYNPTSPGIVTGSTVVIAGSVTDNYSNKEPSGVIRGYDVNTGKLLWVFDTGAADPNAMPGEGTTFVHNSPNAWAPLAYDAKLDIVYVPTGVGTPDIWGGDRTELKERYANSMLAINASTGKLVWNFQTTHHDLWDMDVPSQPSLADIKNKAGQTVPAIYVLTKTGNAFVLDRRNGQPIVPVTEKPVPQTVKRGPQTKGEFYSKTQPFSDLNLAPQDKLTDKDMWGATMLDQLMCRVSFKRLNYDGIYTPPSENGTLVFPGNLGVFEWGGMSVNPDRQVAVMNPIGLPFVSRLIPADPNRAQTAKGAGTEQGVQPMYGVPYGVEISAFLSPLGLPCKQPAWGYVAGVDLKTHEVVWKKRIGTIRDSLPNLFQLPAVKIGVPGLGGSISTAGNVMFVGATQDNYLRAFNVTNGKKLWEARLPAGGQATPMTYEINGKQYVVIMAGGHGSFGTKMGDYLVAYALPDNK
What is the function of this protein?
Catalyzes an exceptionally high rate of oxidation of a wide range of aldose sugars, including D-glucose, galactose, arabinose and xylose, and also the disaccharides lactose, cellobiose and maltose.
What are the official names of this protein?
Quinoprotein glucose dehydrogenase A, GDH-A, Glucose dehydrogenase A [pyrroloquinoline-quinone], Quinoprotein glucose DH.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Periplasmic side.
Protein: DMC1_YEAST
Sequence: MSVTGTEIDSDTAKNILSVDELQNYGINASDLQKLKSGGIYTVNTVLSTTRRHLCKIKGLSEVKVEKIKEAAGKIIQVGFIPATVQLDIRQRVYSLSTGSKQLDSILGGGIMTMSITEVFGEFRCGKTQMSHTLCVTTQLPREMGGGEGKVAYIDTEGTFRPERIKQIAEGYELDPESCLANVSYARALNSEHQMELVEQLGEELSSGDYRLIVVDSIMANFRVDYCGRGELSERQQKLNQHLFKLNRLAEEFNVAVFLTNQVQSDPGASALFASADGRKPIGGHVLAHASATRILLRKGRGDERVAKLQDSPDMPEKECVYVIGEKGITDSSD
What is the function of this protein?
Required for meiotic recombination, synaptonemal complex formation and cell cycle progression.  Recruited to meiosis recombination hotspots by MEI5 and SAE3.
What are the official names of this protein?
Meiotic recombination protein DMC1.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y590_ROSS1
Sequence: MPRVIYFDCFSGVSGDMALGALIDAGVSLDDLRAMLQRLGVGGWELHASREVRGPLAGTRAHVVAPEDHHHRTLTDIRALIAGAPLPSAVVERSIRIFTLLAEAEARVHGTTVDQVHFHEVGALDAIVDIVGVVAGLDLLGVEQVFASPIPPGAGWVRSAHGPIPVPAPATLALLASVGAPVTADETPFELTTPTGAAILAALATFRRPPMRLRAVGYGFGARRMERPNALRVWLGDMDDETDVDQDRQDRTSAEHAGSGESSPVLLETNIDDQPAEQIAYVTERLREAGALDVWCTPIMMKKGRAGVLIAALVPADLEDRMVTILLRETTTLGVRRRAVERYVCARDIITVTTPLGPARVKRKWWRGELIGAAPEYEDCARIARERGVPLTTVYQTVMGRLEDASSVTEH
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: SESQ2_BOVIN
Sequence: MKLNERSVAHYALSDSPADHTGFLRTWGGAGTPPTPSGAGRKCWFVLKGNLLFSFESREGRAPLSLVVLEGCTVELAEAPVPEEFAFAIRFDAPGVRPHLLAADGPAAQEAWVKALSRASFGYMRLVVRELESQLREARHSLDLHRRSSWKAVSSRCKPQAPDRWSPGLENGHSLSRDCSPMGLVEEGGSRPAGRGLAEWELQGPASLLLGRGQSPVSPETSCFSTLHEWYGREIMELRRAWLQRAQENQPECKDQDRP
What is the function of this protein?
Plays a role in endocytic trafficking.  Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
What are the official names of this protein?
Sesquipedalian-2, Ses2, 27 kDa inositol polyphosphate phosphatase interacting protein B, IPIP27B, PH domain-containing endocytic trafficking adaptor 2.
What is the protein family that this protein belongs to?
Belongs to the sesquipedalian family.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
Protein: VF84L_ASFB7
Sequence: MMMFITVYDINQKQKKRYGLRGCNLNLKATVLLLHKRI
What are the official names of this protein?
Uncharacterized protein C84L, pC84L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C84L family.
Protein: NOPC1_HUMAN
Sequence: MEVHGKPKASPSCSSPTRDSSGVPVSKELLTAGSDGRGGIWDRLLINSQPKSRKTSTLQTVRIERSPLLDQVQTFLPQMARANEKLRKEMAAAPPGRFNIENIDGPHSKVIQMDVALFEMNQSDSKEVDSSEESSQDSSENSSESEDEDDSIPSEVTIDNIKLPNSEGGKGKIEVLDSPASKKKK
What is the function of this protein?
Client-loading PAQosome/R2TP complex cofactor that selects NOP58 to promote box C/D small nucleolar ribonucleoprotein (snoRNP) assembly.  Acts as a bridge between NOP58 and the R2TP complex via RUVBL1:RUVBL2.
What are the official names of this protein?
NOP protein chaperone 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y140_PROMH
Sequence: MFGKGGLGNLMKQAQQMQEKMQQMQEEIANLEVTGESGAGLVKITINGAHNCRRVEIDPSLLEDDKEMLEDLIAAAFNDAARRIEETQKEKMASVSNGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PMI0140.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SPIKE_ADE1H
Sequence: MSKRLRVEDDFNPVYPYGYARNQNIPFLTPPFVSSDGFQNFPPGVLSLKLADPIAIVNGNVSLKVGGGLTLQDGTGKLTVNADPPLQLTNNKLGIALDAPFDVIDNKLTLLAGHGLSIITKETSTLPGLRNTLVVLTGKGIGTESTDNGGTVCVRVGEGGGLSFNNDGDLVAFNKKEDKRTLWTTPDTSPNCKIDQDKDSKLTLVLTKCGSQILANVSLIVVDGKYKIINNNTQPALKGFTIKLLFDENGVLMESSNLGKSYWNFRNENSIMSTAYEKAIGFMPNLVAYPKPTAGSKKYARDIVYGNIYLGGKPDQPVTIKTTFNQETGCEYSITFDFSWAKTYVNVEFETTSFTFSYIAQE
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor CXCAR to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface (By similarity).
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: LEUD_MYCLE
Sequence: MQAFRVHTGIGVPLRRSNVDTDQIIPAVFLKRVTRNGFEDGLFATWRVDPSFVLNLSPFDRGSVLVVGPDFGIGSSREHAVWALMDYGFRVVISSRFGDIFHGNAGKAGLLAAQVAQDDVEFLWKLIEQKPGLEITVNLQDRNINAATVVLPFKIDDYTAWRLLEGLDDIALNLRKLDEIEAFESARPAWKPRTLPTT
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PQQA_ACIBY
Sequence: MQWTKPAFTDLRIGFEVTMYFEAR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: IAA4_ORYSJ
Sequence: MEECKGGGMSPSSSMDSSTHPALSTTSSAATARRDLSTDLRLGLSLSTSSSSSLLQAAAAAAAADDSIPSTPRNSQVHADWPPIKPFLRSALQKASAAGGGGARRRRTLFVKVYMEGVPIGRKLDLLLLDGYDSLLIKLCHMFKTPITYADVMECHQQVPGQKAAHVLTYEDQDGDWMMVGDVPWELFLSSVKKLRIARMDKC
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA4, Indoleacetic acid-induced protein 4.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_NITEU
Sequence: MPVVYKRILLKLSGEALMGDGHYGIDRAVVEHIVVEVAGVLQLGVEVAIVVGGGNIFRGMKSAGDGMDRVTADYMGMLATTMNALALHDAMRRNGVVSRVQSALRIDQVVEPYVRGKALRYLDERKVVVFAAGTGNPFFTTDTAAALRGMEMNANIVLKATKVDGIYTSDPLKNKDAQRFQSLTFDEAISKNLQVMDATALTLCRDQKLPINVFSIFKTGALKRVIMGEDEGTSVFV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSB_BURCJ
Sequence: MNLHQFRFVREAVRQNFNLTEAAKALYTSQPGVSKAIIELEDELGVEIFTRHGKRVRSLTEPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPAAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAISDYKELVSLPCFQWHHAAVVPADHPLLERKPVTLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGVGIMADIAFNPERDRGLRLIPVGHLFGSNVTRVALKQGAYLRSYVYTLVELLSPTLNRKLIEQALKGEAESYEL
What is the function of this protein?
Transcriptional regulator preferentially involved in the control of sulfate transport and reduction.  Binds to DNA at target promoter regions.
What are the official names of this protein?
HTH-type transcriptional regulator CysB.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RT12_ORYSJ
Sequence: MPTKNQLIRHGREEKQRTDRTRASDQCPQKQGVCLRVSTRTPKKPNSALRKIAKVRLSNRHDIFAHIPGEGHNSQEHSIVLVRGGRVKDSPGVKSHRIRGVKDLLGIPDRRKGRSKYGAERPKSK
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: C2C4A_HUMAN
Sequence: MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMPRLALAALRNSWVEEAGMDEGAGRTDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLLLGGPPAPRPRAHTYGGGGGPDALLGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCRLLRVPDGLLSRALRAGRSRRLTRVRSVSSGNEDKERRAGSQSPARAPSTSPPSSRVPFPERLEAEGTVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLSLVLRPPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRLLGQGELSLGALLLL
What is the function of this protein?
May be involved in inflammatory process.  May regulate cell architecture and adhesion.
What are the official names of this protein?
C2 calcium-dependent domain-containing protein 4A, Nuclear-localized factor 1, Protein FAM148A.
What is the protein family that this protein belongs to?
Belongs to the C2CD4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMU_ENT38
Sequence: MLNNTMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANELGASNVHLVYGHGGDLLKKTLSDDKLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLIAVETLTRLREAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDASDEQRQIQEINTGILIANGADLKRWLSKLNNNNAQGEYYITDIIAMAHHEGHEITAVHPTRISETDGVNNRLQLSRLERIYQAEQAEKLLLAGVMLRDPARFDLRGTLAHGRDVEIDTNVIIEGQVTLGHRVKIGTGCVIKNSVIGDDCEISPYSVVEDARLDAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDSQLVAPVTIGKGVTIAAGTTVTRDVAENELVLSRVPQVNKQGWQRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCL7C_HUMAN
Sequence: MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHSEGSLQKGTEPSPGGTPQPSRPVSPAGPPEGVPEEAQPPRLGQERDPGGITAGSTDEPPMLTKEEPVPELLEAEAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP
What is the function of this protein?
May play an anti-apoptotic role.
What are the official names of this protein?
B-cell CLL/lymphoma 7 protein family member C.
What is the protein family that this protein belongs to?
Belongs to the BCL7 family.
Protein: TAL_PROMH
Sequence: MTNKLTSLRKLTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDEAIEWARSQSDSREQQIVDACDKLAVNIGLEILKLIPGRISTEVDARLSYDTEACIVKARRLIKLYNEAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRIMDWYKANTDKKEFAPAEDPGVISVTEIYNYYKEHGYNTVVMGASFRNIGEILELAGCDRLTISPALLKELSEAQGEVEHKLSFNGEVKSRPAPITEAEFYWQHNADPMAVDKLSDGIRKFAVDQEKLEKMIADLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_CERS1
Sequence: MIVGVAYAKPTVQVWKHVDVPEGTSAREAIERSGLLAQFPEIDLEVNKVGIFGAICPLDRTLAEGDRVEIYRPIHPEAELLEKKR
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RLMH_RALSO
Sequence: MQLLIVAVGHKMPRWIEDGFAEYAKRMPPELRIELREIKPEQRSGSRTAATVMQLEAARIEAALPKGCRIVALDERGKDLTTAALADALTGWQREGGDVALIIGGADGLDPALKARAHMLMRLSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RD10B_XENLA
Sequence: MHIVLEFFLVTFRVLWAFVLAAAKWFVRPKDKNVAGQVCLITGAGSGLGRLFALEFARRRAQLVLWDINPQSNEETADMVRDIYRQLQAEDSARRANSSADEEVLPCCNLQVYTYTCDVGKRESVYSTAERVRREVGDVYLLLNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPKMMEMNHGHIVSVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAADKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMICTPRLMYIVLCMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNETKNGI
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Converts all-trans-retinol to all-trans-retinal.  Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity).
What are the official names of this protein?
Retinol dehydrogenase 10-B.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: REV_HV1MP
Sequence: MAGRSGDSDEELLKAVRYIKILYQSNPYPKPEGTRQARRNRRRRWRARQRQIHEISERILTTYLGRPTEPVLFQLPPLERLTINCSEDCGQGSERGVGSPQISVESHAALGSGIKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: DAPB_NEIM0
Sequence: MTPLKIAIAGANGRMGRVLVEAVNNHPDTVLSGALEHSGSEALGLDAGYAVGLKTGIAISDDVDAVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTGFDDAGKAAIHTAAEQTGIVFAANFSVGVNLTFHILDTVARVLNEGYDIEIIEGHHRHKVDAPSGTALRMGEVIAGALGRDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHTALFATDGERVEITHKAGSRMTFAAGAVRAAVWVNGKTGLYDMQDVLGLNNR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_ECOSM
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMAQTCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALAFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1697_STRR6
Sequence: MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAVRTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK
What are the official names of this protein?
UPF0154 protein spr1697.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.