PharMolix/UniProtQA huggingface dataset:
Protein: CACO2_MACFA
Sequence: MEKTIEDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCRYTFTQNFIPRQKDWIGIFRVGWKTVREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDQDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSCVSLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETEQLEHLKKENGHLFLSLTEQRKDQKKLEQTVEEMKQNETTAMKKQQELMDENFDLSRRLSEKKMIYNALQREKERLEGENDLLKRENSRLLSYMGLDFNSLPYQVPTSDEGGAGQNPGLVYGNPYSGIQESSSPSQLSIKKCPICKADDICDHTLEQQQMQALCLNCPICDKIFPATEKQIFEDHVFCHSL
What is the function of this protein?
Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity).  Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity).  Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (By similarity).  Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (By similarity).  May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (By similarity).
What are the official names of this protein?
Calcium-binding and coiled-coil domain-containing protein 2, Antigen nuclear dot 52 kDa protein, Nuclear domain 10 protein NDP52, Nuclear domain 10 protein 52, Nuclear dot protein 52.
What is the protein family that this protein belongs to?
Belongs to the CALCOCO family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein.
Protein: YCGQ_BACSU
Sequence: MFRLLVLMGFTFFFYHLHASGNLTKYINMKYAYLSFIAIFLLAILTAVQAYLFIKSPEKSGHHHDHDCGCGHDHEHDHEQNKPFYQRYLIYVVFLFPLVSGIFFPIATLDSSIVKTKGFSFKAMESGDHYSQTQYLRPDASLYYAQDSYDKQMKQLFNKYSSKKEISLTDDDFLKGMETIYNYPGEFLGRTIEFHGFAYKGNAINKNQLFVLRFGIIHCIADSGVYGMLVEFPKDMDIKDDEWIHIKGTLASEYYQPFKSTLPVVKVTDWNTIKKPDDPYVYRGF
What are the official names of this protein?
UPF0703 protein YcgQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0703 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA_MAGMM
Sequence: MLILTRRVGESLHIGDDIKITLLGIKGNQVRIGIDAPRDVEVHREEIYDRIRRETRKANRRTAEETLDQASRLLSQK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_SOLUE
Sequence: MSGLSRIGVAIDSDLLDKFDSLIGQRGYTNRSEAFRDLIRDELVEKTWESPESQVVGTVTLVYDHHVRLLNEKLTGIQHDFHHSILSTLHVHLDHDNCLEVLVVRGRSADVRKVADVLISTKGVKHGRLTITTTGAEMK
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: IF2_FRATO
Sequence: MAEITVGQLAQQTNKEVDALLKQLKSFGIEKSSEKDTLTPTEMKTLLEKINSAKNTATRKKVTSVKLDGKHKINVSVKRKRRVAKKMEQQESTTLEQPQELETMVQEVSQQVDIVKEQDNIEQIVENKEAVKVQEQRQAEIAKPVIKDSGFKITAMPEIKIEEIVAEDDEGLAASDKQAKKKAAKKVFSEAVNTNTKYKREEEEKKSKAKKAGGKGFKKANPRQLSQLAGDLESFDEFGAKKGKLKAPKVKKQEFTKPVENTVRTVEIHEGITVSELAQKMAVKGAEIVKVLFNMGVMATINQSLDQDTAILIVEEMGHKYTLHNENALEEAVTIVDRSSYKKISRAPVVTIMGHVDHGKTSLLDYIRQTRVVAGEAGGITQHIGAYSVKTDKGSITFLDTPGHEAFTSMRARGAKSTDIVILVVAADDGVMPQTEEAIQHAKAARVPIVVAVNKIDKPEADSDKVISELAQRNVIPESWGGDVMFVNVSAKTGEGVADLLEAVLLQSEVLELEAFAEGLAEGVVIESRLEKGRGPVATVLVQNGNLKQGDNILCGTEYGRVRAMHNDLGKKIKAAGPATPVEILGLSGVPAAGDEMVVIENEKKAKELAAQRSQKQKEAKIAQEQSLKLSNMFNNMGKEGEQQVLKIILKGDVQGSVEAIRESLLKLSTDEVKVDIIASGIGAITSSDVTLAVASTAVVIGFNVRADSAAKKLAETDGVEFRYYNIIYDLIDDVKKAMSGLLSPEMKEQIIGIAEVREVYRSSKFGSIAGCMVIEGVVKRTNPIRVLRNNVVIYEGTLESLKRFKDDASEVKKGLECGIGVKNYNDVREGDQIEVFEVIEVAKEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_TRIL1
Sequence: MGDITRFGISIDSDLLDSFDRLITRKGYQNRSEAIRDLIRATIVEEKMDAGHEEMVGTVTMVYNHHVRDLADKLTEHQHQHHHQVISALHVHLDAHNCLEVLVLKGSSAEIKQIADELLGVKGVKHGKLFLTSATPEHH
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL19_PSEAE
Sequence: MTNKIIQQIEAEQMNKEIPAFAPGDTVIVQVKVKEGDRQRLQAFEGVVIAKRNRGLNSAFTVRKISNGVGVERTFQTYSPIVDSLSVKRRGDVRKAKLYYLRALSGKAARIKEKLV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TRHO_BRUAB
Sequence: MSNLPFTVAALYCFAPLPQYESLREPLAQLCCANGIKGTLLLAAEGINGTVAGSAGAIEKLIAHITAIPGLGEPELKYSHASEMPFHRMKVRLKREIVTMGVEGIDPLKSVGTYIAPKDWNALIADENTVVVDKRNDYEYAIGTFEGAIDPQTRTFREFPEWVKQNRDRLEGKKIAMFCTGGIRCEKATAFVKGLGFDDVYHLKGGILKYLEEVPREQSMWNGECFVFDERVAVGHGLAESDVELCRACRRPLTPQDKLSQFFEEGVSCAGCYAERTPEDRARYAERQKQVKLAEKRGANKHIGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL17_ACIF2
Sequence: MRHRKSGKQLNRNSSHRQAMFANMMVSLFHHERIVTTLPKAKELRRFAEPMITLAKEATVAKRRLAFSRLRDRQAVVKLFDDLGPHYLARPGGYLRIVKYGFRAGDNAPLAIVELVDRQTAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SECE_RICS2
Sequence: MFKEYKIYKFFEQVKQETYKVVWPTRKELVASTLVVVVAVFIFSLICLVLDYSIHNIMQLLLNIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FMT_MYCPA
Sequence: MRLVFAGTPEPALPALRRLLDSPRHEMIAVLTRPDAASGRRGKPEPSPVAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELLAVPPHGWINLHFSLLPAWRGAAPVQAAIAAGDIITGASTFRIEPALDSGPIYGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAEGVSIAPKITVEQARVRWDLPAPVVERRIRAVTPNPGAWTVISDLRIKLGPVRLGAASDLPAPPEPLPPGAIHVDRKSVWVGTGSDPVRLGQIQPPGKKFMNAVDWARGARLDPAARAT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: EI3G1_DROMO
Sequence: MPGVETIKSSWADEVELDYGGLPPTTETIENGHKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGDSKNDKPGPNSQTTMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNLMEKKAAAAASAAVDAPKSGKYVPPFLKDSQKGGMGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-1, Eukaryotic translation initiation factor 3 RNA-binding subunit 1, eIF-3 RNA-binding subunit 1, Eukaryotic translation initiation factor 3 subunit 4-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_PHOLL
Sequence: MQLTPREIEKLMVYTLADVALKRKSRGLKLNYPEAVAIITAAALEGAREGKTLEEVMDDSRHVLTKEDVMDGVADLIPHVQVEAIFTDGSRLVTVHDPIQ
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGY_BACSU
Sequence: MNRMFRVLGFWTGIFAVMFYLGDMKDASLLFFGQTILFVFLSYLNLTERMYIYIFGAYLTIFFAGFTYYSIFIMVPGGGGH
What are the official names of this protein?
Uncharacterized protein YqgY.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AL2C4_ARATH
Sequence: MENGKCNGATTVKLPEIKFTKLFINGQFIDAASGKTFETIDPRNGEVIATIAEGDKEDVDLAVNAARYAFDHGPWPRMTGFERAKLINKFADLIEENIEELAKLDAVDGGKLFQLGKYADIPATAGHFRYNAGAADKIHGETLKMTRQSLFGYTLKEPIGVVGNIIPWNFPSIMFATKVAPAMAAGCTMVVKPAEQTSLSALFYAHLSKEAGIPDGVLNIVTGFGSTAGAAIASHMDVDKVSFTGSTDVGRKIMQAAAASNLKKVSLELGGKSPLLIFNDADIDKAADLALLGCFYNKGEICVASSRVFVQEGIYDKVVEKLVEKAKDWTVGDPFDSTARQGPQVDKRQFEKILSYIEHGKNEGATLLTGGKAIGDKGYFIQPTIFADVTEDMKIYQDEIFGPVMSLMKFKTVEEGIKCANNTKYGLAAGILSQDIDLINTVSRSIKAGIIWVNCYFGFDLDCPYGGYKMSGNCRESGMDALDNYLQTKSVVMPLHNSPWM
What is the function of this protein?
Involved in ferulic acid and sinapic acid biosynthesis by oxidation of conyferylaldehyde and sinapaldehyde, respectively.  Can oxidize L-lactaldehyde.  Possesses activity on acetaldehyde and glycolaldehyde in vitro.
What are the official names of this protein?
Aldehyde dehydrogenase family 2 member C4, ALDH1a, Protein REDUCED EPIDERMAL FLUORESCENCE 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: EFTU_BACC3
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKAGGAEARGYDQIDAAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYGFPGDDIPVIKGSALKALQGEADWEAKIIELMAEVDAYIPTPERETDKPFLMPVEDVFSITGRGTVATGRVERGIVKVGDVVEIIGLAEENASTTVTGVEMFRKLLDQAQAGDNIGALLRGVAREDIQRGQVLAKSGSVKAHAKFKAEVFVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIIQLPEGTEMVMPGDNIEMTIELIAPIAIEEGTKFSIREGGRTVGYGVVATIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_RHOBA
Sequence: MSTRSRARKRSRVRSRTRRKDPIFVDGHRPRPMYVDYKDLELLSKMVNRQGRIMGRRKSGCTAASQHAVTAAIKRARFMALLPYVGE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SCPB_STRMU
Sequence: MTPLSKIEALLFVAGEDGLSLRQLATLLDIPVTALLQQLEKMAQKYERDDNSALSLLESSKTYKLVTKKDYADLLRQYSKTPINQSLSRASLEVLSIIAYKQPITRIEVDNIRGVNSSSAISKLQAFDLIQEAGKKEVLGRPNLYVTSDYFLDYMGINSLEELPDASSIELKDEEFTLFDNKENEEQISENVKEENEN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PSAB_HUPLU
Sequence: MASRFPRFSQGLSQDPTTRRIWFGIATAHDFESHDNITEERLYQKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWIQDPLHVRPIAHAIWDPHFGQPAIEAFTRGGASGPVNIAYPGVYQWWYTIGLRTNQDLYTGALSLLILSAIFLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGEHVRWDNLLTALPHPQGLGPFFAGQWSVYAQNADSSSHLFGTSQGAGTAILTFLGGFHPQTQSLWLTDIAHHHLAIAVVFIIAGHMYRTNFGIGHSMKEILEAHTPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFLIRDYNPEQNEGNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPVSAQWIQSAHGKALYGFDVLLSSANSPAFNAGQSIWLPGWLDTINNNSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKEFGYSFPCDGPGRGGTCDISAWDAFYSAVFWMLNTIGWVTLYWHWKHITLWQGNVAQFNESSTYLMGWLRDYLWLNPSQLINGYNPFGMNSLSVWAWMFLFGHLVWAIGFMFLISWRGYWQELIETLAWAHERTPLANLVRWKDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1938_MYCSS
Sequence: MTSTRGEAAGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAVNASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAGDHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGPLGVGRLLDHAAVTGVAQAHGKTPAQVLLRWSIQLGNVVIARSANPDRITSNLEVFDFELTDDEMATLNGLDEGTRFRPDPETYTGP
What are the official names of this protein?
Uncharacterized oxidoreductase Mmcs_1938.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: KAD_NEIMH
Sequence: MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSKLEGEHAPKYIKVDGTQAVEAVKAEVLGALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDAH2_BOVIN
Sequence: MGTPGEGLGRCSHALIRGVPESLASGEGAAAGLPALDLAKAQREHGVLGGKLRQRLGLQLVELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEMGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVTSTSHLRGLCGMGGPRTVVAGSSEAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGQPGLPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHN
What is the function of this protein?
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS.  Has therefore a role in the regulation of nitric oxide generation (By similarity).
What are the official names of this protein?
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Translocates from cytosol to mitochondrion upon IL- 1beta stimulation in chondrocytes.
Protein: MNME_YERPY
Sequence: MSTTDTIVAQATPPGRGGVGILRVSGRAASEVAHAVLGKLPKPRYADYLPFKDVDGSTLDQGIALYFPGPNSFTGEDVLELQGHGGPVILDLLLKRILALPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSAVNSLQGAFSARIHQLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEGQLNGVMADLEQVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREANDEVERIGIERAWNEIEQADRVLFMVDGTTTDATEPAAIWPEFMARLPATLPITVVRNKADITGETLGLTEVNGHSLIRLSARTGEGIDLLRDHLKQSMGFTSNTEGGFLARRRHLQALETAARHLIQGHEQLVSAYAGELLAEELRLAQQSLSEITGEFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV26
Sequence: MENLCQRLNACQEKILDYYELDSNKLTDQIDYWKLVRYECAIFYKAREGNMQCINHQVVPSTVVCKQKAWQAIEIHIALQSLINTDYNTEAWTMRDTSYEMYMTEPKHCFKKEGTTVTVVFDCNKENTMDYIRWKYVYYKTDIGWCKGTGDVDAKGIYYTQGAYKQYYVDFKQEAEKYGTGVQWAVHVCGQVICCPEFVSSTCSSNQISTAKTAEPVSNATTQTTEAYVPVGTKETEAPYPGKRRRLSGPDTTVTTVTTVTTAATQPGQSVDYTNNNLHSTSGGHHPGRDTSSDQTVFIVHLKGDTNSLKCLRYRFKKHKGLYCNVSSTWHWTSNDTNQQGIVTITFNSITQRNNFLTTVKIPQSITSTLGIMSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CSGC_ECO45
Sequence: MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQILSLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQWPPSSEKS
What is the function of this protein?
Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers.  Assembly may also require CsgE.  Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity).
What are the official names of this protein?
Curli assembly protein CsgC.
What is the protein family that this protein belongs to?
Belongs to the CsgC/AgfC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TF24_SCHPO
Sequence: MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPEIGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGSLTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILWMLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQLQNKNLGKESLSKKNNTTNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITEETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAISFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKGLEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKKEGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDEHKLAFRCPRGVFEYLVMPYGISTAPAHFQYFINTILGEAKESHVVCYMDDILIHSKSESEHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQPKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLVSPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSDKEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFNFEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTNDTKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGIELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSMDFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEIIADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTWVDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQTVKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVLQKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKNREQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI
What are the official names of this protein?
Transposon Tf2-4 polyprotein, Retrotransposable element Tf2 155 kDa protein.
Protein: SYR_FRATN
Sequence: MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVVSDVHLGDWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPVTVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVALWQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTAVRAKSILRKIFGDNYDIKSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPITNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_THEVB
Sequence: MTDYAAHQQALDRDCLTLSRHVLQQLQSFDAAAQDLSALMNRIALAGKLIARRLSRAGLMEGVLGFTGAVNIQGEDVKKMDVYANEVFIAAFKQSGLVCRLASEEMAQPYYIPENCPIGRYTLLYDPLDGSSNVDINLNVGSIFAIRQQEGTDLDSTAADLLQDGHQQIAAGYILYGPSTMLVYSLGKGTHVFVLDPSLGEFILAIENLQIPASGAIYSVNEGNFWAWEEPIRNYVRHVHRQPGYSARYSGALVADIHRILMEGGVFLYPGTQKNPAGKLRLLYEAAPIAFLVEQAGGKASTGTQPLLDVVPDHLHMRTPLIVGSPENVALVESFIQQTPAQPTVTQV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_ROSCS
Sequence: MKILVIHGPNLNMLGRREPEVYGSVTLDEINAILQERAAAVGVTLLTVQSNHEGALIDFLQAEGWDADGIIINPGALTHYGLALRDALAMLKAPIIEVHLSNVYRREPFRHTSVIAPVATGQIAGLGWRGYLLAIEWLLGTRGQGPGTRDQALGTRD
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: Y2658_STAAR
Sequence: MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDHKALLQCIEAGNNKLRFYQSAFYQELFYFYYDLFKSDDDIYTKFKTDMLLQALSTRVFDFQIEHRNISIEAYRNYLLNIYLDEVERND
What are the official names of this protein?
HTH-type transcriptional regulator SAR2658.