PharMolix/UniProtQA huggingface dataset:
Protein: PKHA7_DANRE
Sequence: MAAPLRRDTLPDNGSYGVCRDGRVFFIDDEARATTWLHPRTGQPVNSGHMIRSDLPSGWEEGFTKEGASFFIDHNQRTTTFIHPVTGQISTENSDFRLQDQPGGRMLKQPSSTISEASTTVTTSTVDSTSGSKGSRSSGRVHSFGKRDHAIKRNPSVPVVVRGWLYKQDSSGMRLWKRKWFVLADFCLFYYKDSREESVLGSIPLPSYTIAPVGPEDHISRKYAFKAEHTGMRTYYFSADTQEDMNGWVRAMNQAALMQTHTVKRDECGHPDHVNVSEKLKKQAVPQTNHINSYVIPKPEVIQSDGLPEDKREGFVGEVEIQVTPREMEQARGKSPASRVVEVEVLAPGSTPPSRVASRAPSRAVSTPPVVQRNGTPIEQNGMPGCQRGATPSAQTPVQVQRRSTLEQVENWVKVQKEERHGLVSTESTVPRRTPPIHPKYGTMDKYQSLPKTSRQSPPAPHHQLPSEYKYSHDRLNHFQKIHGHTKRPTTHDNTVWQLFEWQQRQQFRHGSPSAPVYTPAPDYSTAVSSTRNNSDVSRSVSVPPTLADIPPPGPPGARLMSPRRPHTPAERVTVRPLEDRPIVEVPPSNSPHRLRSYKSATIERRSMPPSAYITHTVSAPSLHGKTADDTYMHLKKDLEYLDLKVSGTEALKGRPAKPVKVAESDVDVTLSRLCEQDKILQELEFRLSGLKDDKDKLESVLDVSHQQMEQYKDQPSHTDKIAYQQRLLQEDLVHIRADISRVSTEMERAWDDYSRMEQSVEQLRDVLQTQMTLCTSPQEKNQLKRELWRIEDVMTGLSSTKETFKITVDSVKNPERKLVPSVIESTVPSRCMTPSAAEVRSPQRSLTSSPLPLPLDNEDLRNRHPVPNWEEDDAPPRPPLPLLYDEDTPPVVPPLPKETSVIRHTSVRGLKRQSDERKRDRESSYSNGDYRLELRSYLSEPELPVSAHGADHVDPGYLTLQRRGLSGSSSRINQYGVASCSLRRDLELSTMERPKSALERLCSGEPQLEQQSQPQRVRMSVEEQLERMKRHQRALVRERKRNLSQGERHHSRASTRPVNSDPGSALFVEPYRPASDEWLTVRARPVMELELEPLDFEFDITRELSTPQKVWIPQRLIDDESDEDLSPEEKETRSRTVAKIKTLLSKSSMRSSEQMDFSDLDLALQQQERIMSVPRALATEASIKRRQVTAKAMSEG
What is the function of this protein?
Required for zonula adherens biogenesis and maintenance.
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 7, PH domain-containing family A member 7, Heart adapter protein 1.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: HFQ_CLOD6
Sequence: MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYIILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: IQCE_MOUSE
Sequence: MSLGTTDIASETGDDSLSAITFESDIESKTKRKSFHKPPSTSPKSPYYSKPRKVTSWRSLKTAGSMPLSSRMSLTPQKLWLGSSKQGSVAQPPSPTLTSEHAWTHPPSCTPDYLTEAVRAKRADLRRSGSHGHVSGTSVYREKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPSRGPDFVRTLAEKKPDTGWVITGLKQRIFRLEQQCKEKDNTINKLQTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPMVEKKLGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTISKIKGYGDWSKPRLLRRIAELEKKVSSSESPKQSTSELVNPNPLVRSPSNISVQKQPKGDQSPEDLPKVAPCEEQEHLQGTVKSLREELGALQEQLLEKDLEMKQLLQSKIDLEKELETAREGEKGRQEQEQALREEVEALTKKCQELEEAKREEKNSFVAVTHEAHPELHAPSPCSRHSEPDSDNSAGEEGSSQPPAPCSEERREAAIRTLQAQWKAHRRKKREAALDEAATVLQAAFRGHLARSKLVRSKVPDSRSPSLPGLLSPLNQSSPAPRVLSPISPAEENPTQEEAVIVIQSILRGYLAQARFIASCCREIAASSQRETVSLTPSGSASPPSLRASPGVIRKELCASEELRETSASEPAPSVPYSAQGGHGDCPSSSSLEAVPSMKDAMCEERSSSPRSAGPSLAEPSPPELQPLSPPPVEDICSDDSDDIIFSPFLPRKKSPSPF
What is the function of this protein?
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:24582806).  Required for proper limb morphogenesis (By similarity).
What are the official names of this protein?
IQ domain-containing protein E.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner (PubMed:24582806).
Protein: MNHG1_STAA9
Sequence: MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTKKTKVDEISEDLKDTKL
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G1, Mnh complex subunit G1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HXA9A_TAKRU
Sequence: MSTSGTLTSYYVDSLILPENEELSVPRYSAGPGHQHSRQPASIGDPHSELGTCSFPSKPPVFGPSWSHVPAQFPGTVSSVYHHHYGHHQGPVGTETDGRYQSWLLEPMSGSLPMAGLPTTHHYGIKPDGLGVRSGGALPGSHTALLLSDYANGTVATAPPVEKDAVSSHTGDGVDTEEKPGLDPSKSAVYITFYLYRTYSGDRDNPVSNWLHASATRKKRCPYTKHQILELEKEFLFNTYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKFNKDGAPKDD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A9a, HoxA-9.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YMIA_ECOLI
Sequence: MRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVVVALLIWKVWG
What are the official names of this protein?
Protein YmiA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AASS_HUMAN
Sequence: MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP
What is the function of this protein?
Bifunctional enzyme that catalyzes the first two steps in lysine degradation.
What are the official names of this protein?
Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the saccharopine dehydrogenase family.
Protein: RS182_MYCTO
Sequence: MAAKSARKGPTKAKKNLLDSLGVESVDYKDTATLRVFISDRGKIRSRGVTGLTVQQQRQVAQAIKNAREMALLPYPGQDRQRRAALCP
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYE_PYRAE
Sequence: MNVEEIAFKYALANAVKYGGKADVKAVMAKLMAEVPELRARAREVKQIVDAVVARVNSMPLEEQRRILRERWPELLEERRAEQRRPGLEGLPELPNVRGGVVVRFAPNPDFVLHLGSARPAILNYAYRIKYGGKFILRFEDTDPRIKSPLVTEEVNAYESIREDLRWLGVRWDEEYIQSQRMEIYYEHAKKLLEMGAAYVDLCKPEEWRRLRNEKKACPHREQPPEVNLELWDKMLEGRFKEGEAVLRIKTDLTHPDPSVRDWVAFRIIDTSKTPHPLTGDKYIVWPTYNFAVSIDDHLMGVTHVLRAQEHSVNTIKQSYVFRHFGWEQPVTIHFGRLRIEGATLSKSKLKAMRIKYDDLTLPTLAGLRNRGIVPEAIWDLILSVGIKPSDSTVALANLFAFNRKHIEPIADRYMYVADPVKLVFEADKELTAHVPFHPSFKERGERTYRLGPGRVEVYIQRRDAVAGKVVRLMELANVEIVRVEGDVAYGRIHSYSLDEAKKIGAPIIQWVWDPVEITVIKPAGVGRKEVEVGLGEGWLERVEVGKYVQFFRYGYLKKRGPREFVFLHD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPE_SCHPO
Sequence: MKIYPDLKQVQELAEKHKANKIPIYGVIPADMLTPSVAYLKLNQGKKYSFILESVTQGESVSRYSFIGSPYRILMANGKTDPLARLERELKEVKTAPVEGLPSFSGGAVGYVSYDCIKYFEPTTEMPLEDTLGLPEAMFFMTDDLVAFDHAYQTVKIISHVCIQQGRPIEEAYEAAVFKINMLKKKLESPEIPLPEQKKVHLGYEAKSNVGEDGYKAFVSNLKEHIFNGDIFQAVPSQRIARRTDLHPFNLYRHLRTVNPSPYMFYIHCDDFDIIGASPELLVKSEHGRIINHPIAGTVPRGKTKEEDEAYAKDLLASVKDRAEHVMLVDLARNDVSRVCDLDTTSVDKLMTIEKFSHVQHLVSQVSGVLRPDKTRFDAFRSIFPAGTVSGSPKVRAIQLVYGLEKEKRGIYAGAVGRWGYEDDNMDTCIAIRTMVYKDGTVYLQAGGGIVFDSDEQDEYVETLNKLRSNVTAIEETEKLYAEEENSSA
What are the official names of this protein?
Probable anthranilate synthase component 1, Anthranilate synthase component I.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: GET1_DANRE
Sequence: MAAGFNWFLVLSSVFLCNLVKTFLPSISSFLSKIFHKDADQEMEMRTEIQNMKMELSTISMMDEFARYARLERKINKMTDQLKTLVKSRTAQQAKMKWIVNIAFYILQAALMISLILKYYADPVTVVPSKWIAPLERLVAFPSGVAGGVGITCWLVVCNKVVALILQAVS
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER) (By similarity).  Together with CAMLG/GET2, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (By similarity).  Required to ensure correct topology and ER insertion of CAMLG (By similarity).
What are the official names of this protein?
Guided entry of tail-anchored proteins factor 1, Tail-anchored protein insertion receptor WRB, Tryptophan-rich basic protein.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AVLB6_WHEAT
Sequence: MKVFILALLALAATTAIAQLETTCSQGFGQSQQQQQPGQRQLLEQMKPCVAFLQQKCSPLRMPFLQTQVEQLSSCQIVQYQCCQQLAQIPERTRCHAIHIVVEAIIQQQSQQQWQEPQQQAQHKSMRMLLENLSLMCNIYVPVQCQQQQQLGQQQQQQLQEQLTPCTTFLQQQCSPVTVPFPQIPVDQPTSCQNVQHQCCRQLSQIPEQFRCQAIHNVAEAIRQQQPQQQWQGMYQPQQPAQLESIRMSLQALRSMCSIYIPVQCPAPTTYNIPLVATYTGGAC
What is the function of this protein?
Seed storage protein.  Might be integrated via inter-chain disulfide bonds within the glutenin polymer (By similarity).
What are the official names of this protein?
Avenin-like b6, Avenin-like protein s1.
What is the protein family that this protein belongs to?
Belongs to the prolamin family.
Protein: RLMB_RALSO
Sequence: MSKSKLLIGFHAVTARLRHDARSIDEIYFEANRRDRRMQDFLKAAEAAGVRMIPADNERLRGIAGTDRHQGVVAKAEALSLALNLDELLDGIEGPPLLLVLDGVTDPHNLGACLRVADAAGAHAVIAPKDRSVGINTTVAKVASGAAETVPYITVTNLARTLRELQQRGVWVIGTADEAEQDLYRADFKGPIALVMGAEGEGMRRLTRETCDTLVSIPMAGSVESLNVSVASGVCLFEAVRQRSVVPAK
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PHYAS
Sequence: MLHTIKPVANARKTTKRLGRGPGSGTGKTSGKGHKGQLARSGKTLRPGFEGGQIPFFQRIPKRGFHNFAQKKYAVLNLTTLQNFPEDSVITPQLLLEKKIIKDPLSGIKVLGQGTLTKKLVVKASKFSRQAEASILAVGGKIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FARB_NEIGO
Sequence: MDYPPLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLGAATTQGTWVITSFSVANAVSVPLTGFLAKRIGEVKLFTAAAAGFVIASWLCGIAPNLQSLVVFRILQGFIAGPLIPLSQSLLMASYPPAKRMLALALWAMTVVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAWITWKHLKHRETATVRTPTDYVGLTLMMVGIGALQMMLDRGKELDWFASGEIITLGITALVCLSYFIVWELGEKYPIVDLSLFKDRNFTVGAIATSLGFMVYMGTLTLLPLVLQTNLGYTSAWAGLAAAPVGILPVFLSPLIGRFGNKIDMRLLVTASFLTFAFTFYWRTDFYADMDIGNVIWPQFWQGVGVAMFFLPLTTITLSHMKGGQIAAAGSLSNFLRVLMGGVGVSVVSTLWERREALHHTRFAEHITPYSATLHETAAHLSQQGISDGQTLGIINNTITQQGFIIGSNEIFLAGSILFIVLIPIVWLAKPPFHSGGGGH
What is the function of this protein?
Mediates resistance to long-chained antibacterial fatty acids (FAs) (PubMed:10447892).  Function is dependent on the MtrE outer membrane protein (PubMed:10447892).
What are the official names of this protein?
Fatty acid resistance protein FarB, Efflux pump protein FarB.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYC1_LYCSI
Sequence: GKLQAFLAKMKEIAAQTL
What is the function of this protein?
Inhibits growth of Gram-positive (S. aureus, B. subtilis) and Gram-negative (E. coli, P. aeruginosa) bacteria and fungi (C. albicans).
What are the official names of this protein?
M-lycotoxin-Ls3a, M-LCTX-Ls3a, Lycocitin-1.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHED_THIDA
Sequence: MNSAIEEQLATNLYYDRNFDCETAKILPGEYYFTAKPMLIVTVLGSCVAACIRDRVSGIGGMNHFMLPDGGGDPGNPLSASMRYGAYAMEVLINQLLKAGARRENLEAKVFGGGNVLRGFTTMNVGERNAQFVRDFLRAENIRVVAEDLNDVHPRKVYFFPRTGRVLVKKLKQLNNYTLVKREQDYASRLKSNVVAGEVDLF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: YPA4_ASCIM
Sequence: VGVRSYYMKYIIVGFTLPRPHNPPAFILSFRPKRINTGSYPPIQNCKFLIADGSRKVFT
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF4A/ORF4B.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURD_WOLPM
Sequence: MQLNKYKNQNVAVFGLGKTGLSAINALTKSGARIYAWDDHEEQIANAKMMYKKCNFIHPKEYNWHEISALVLSPGVPTEPHWIVKLARRFDCKIKSDIELFLEAKTTNQKVIGVTGTNGKSTTTSLIGHILKSAGKKVAIGGNLGVPVLDLERDAEIYVIELSSFQLELMNEINVDISALLNITPDHIDRHGSMENYIATKLKLINGSEVAVIGCDNEITADIFNKFTGDKIPISVTYSPMSFQCVTLESRKEKPLPTTQMTEGGARDLISLAGNNLLDYSEQITGIDRNYLDPSVSYLDDKRGTGIQKISLKLENHSLSVSDVKINLISNAENIAATYAVCKVLGVDSNTIINGIKSFSGLRHRNELLGKIRNVFFVNDSKATNAKSSEKAILSYENINWIAGGRSKKGGIESLSKHFTRVRKAFLIGESTEAFANVMENKVDYVKCCNLEDAFRLAFEEALNSAEEVTILLSPACASFDQWKNFEERGEAFCRMFENLRYNHTCCLV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_NEUCR
Sequence: MAPKKSKSDAQSIGAKLALVIKSGKVVLGYRSTLKALRSGKAKLILISANTPPLRKSELEYYSMMSKTAVHHYTGTNIELGTACGKLFRCSTMAILDAGDSDILADQQQ
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: RRF_DEIDV
Sequence: MADMKSIQADARERMGKAIEALESNLSVLRTGRANPGILKKVIVDYYGSTMPIDQVASITTPDARTLVITPWDRGALGPIEKAIRDSDLGLNPNNKGDTIFISLPMLTEERRKDLVKNAKNYAEDARIAVRNIRKHALDEVKKVEGVGDDEIKRGEAEVQKITDEFIARVDSTFHKKEQEILG
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_CHOFU
Sequence: MMRKWLYSTNHKDIGTLYFMFGIWAGMVGTSLSLLIRAELGNPGSLIGDDQIYNTIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSIMLLISSSIVENGAGTGWTVYPPLSSNIAHSGSSVDLAIFSLHLAGISSILGAVNFITTIINMRPNNMSLDQMPLFVWSVGITALLLLLSLPVLAGAITMLLTDRNLNTSFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIISQESGKKETFGCLGMIYAMMAIGLLGFVVWAHHMFTVGMDIDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQINYSPSMLWSLGFVFLFTVGGLTGVILANSSIDVTLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWYPLFTGLALNPYLLKIQFFTMFIGVNLTFFPQHFLGLAGMPRRYSDYPDTYTSWNIISSLGSYISLVATMLMLMIIWESLINKRIILFPLNMNSSIEWYQNLPPAEHSYNELPILSNF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: O16L_CONAB
Sequence: VLIIAVLFLTACQLTTAETSSRGEQKHRAPRSTDKNSRMTKRCTPGGEACDATTNCCFLTCNLATNKCRSPNFP
What are the official names of this protein?
Conotoxin AbVIL.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_BUCA5
Sequence: MVKIRLARYGTKKRPFYKLVVADSRFSRNGRFIERLGYFNPIAKGKSEILKLNLERIEHWTNQGAQMSERTKKLIKQKR
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YACG_PECAS
Sequence: MTTEITTVKCPTCKQAVIWDAASIYRPFCSKRCQLIDLGEWADEEKCIPSDDMVSDSEDWSETR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: YL755_MIMIV
Sequence: MDKINKIKINETEYYHSDDILALKMKKFDKCVNGRRLIDDFNIKKPNFIYAAFKDDEWIKTDGRSRKFDKVFVKVSWFENYIQENDSDDDCSENDSDGDCSENDSDNDYSENESDCELYNEKNNKCTRYY
What are the official names of this protein?
Uncharacterized protein L755.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L5 family.
Protein: LON_TREPA
Sequence: MAKNTDIEHDAHEPAGHGDVRESAVENPSASAVSDGEERATFAPEVAPQTDTESAQGAAQESEPEVQRAGEAEKGVPEKAKAVVPLDELLPQKVHLIPLTGRPIYPGIFTPLLISDEDDVRSVESAYSDSGFIGLCLVKTDTQNPTISDLYEVGSVARIVKKINLPDGGLNVFISTQKRFRIRKHVHHSKPIVAAVQYLSDLIEGDPLEIKALVRGLIGEMKELSENNPLFSEEMRLNMINIDHPGKIADFIASILNISKEEQQRTLEILDVRKRMEEVFVYIKKEKDLLEIQRKIQNDLNSRVEKNQREYFLREELRSIKEELGLTTDPKERDQRKFRALIDSFHFEGEVKEAVESELEKLSLTDPNSPEYSVGRTYLETVLSLPWHAPEKEEYDLKKAQKLLDEDHYGLENVKERIVEYLAVRKLRADTKGSIILLVGPPGVGKTSVGKSIARAIHKPFFRFSVGGISDEAEIKGHRRTYIGALPGKVLQGLKIVKTKAPVFMIDEVDKIGSGARGDPAGALLEVLDPEQNTTFRDHYLDLPFDLSHIVFVLTANSTDPIPRPLLDRAEIIRLSGYIDTEKVEIAKRHLVPKTLEKNGLKRACVSYRKEVLLHLVHSYARESGVRGLEKSLDKLHRKLATEIVLGKRSFDDKCLMDEALIGTFLGKPVFRDDMLKDANKVGTAVGLAWTGMGGDTLLVEAITIPGKASFKLTGQMGAVMKESASIALSWLRRYSAQQRIASPNWFEKRAIHLHIPEGATPKDGPSAGITMTTTLFSLLTQQKVKPRLAMTGELSLTGQVLPIGGLKEKTIAARRGGIKEIIMPKANVRDLDEIPEHVKKGMVFHLVESMEEVLSLAFPKGKRVRAGTAAQSASPETLTG
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_SALA4
Sequence: MIIPALDLIDGTVVRLHQGDYARQRDYGNDPLPRLQDYAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIGSTAVKSPDVVKGWFERFGAQALVLALDVRIDEHGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEICARYPQIAFQSSGGIGDIGDIAALRGTGVRGVIVGRALLEGKFTVKEAIQCWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA2_CLOPE
Sequence: MNRLIINGGKALKGSIEINGAKNAAVAILPAAILASKGECIIDNVPDIADVHCLERIIRSLGCNVEKLDNNTLKINAEEIKTVEACGNDVRKMRASYYFIGALLARFKEAKVELPGGCPIGVRPIDQHIKGFEALGAKVSIEHGAVNIMAEKLIGTNIFFDVVSVGATINLMIAATLAEGTTVLENAAREPHVVDVANFLNAMGANVKGAGTDVIRIKGVKELKGCNYSVVPDQIEAGTFMIAAAATRGDVTIQNVIPKHLESISAKLLEMGAKVEEGDDSVRVYVDGDLKGVNLKTAPYPGFPTDVQQPMCTLLSTAKGRSIIVETIWENRHKHVDELKKMGATIKVEGRSAIIDGVDRLTGAVVKATDLRAGAAMVIAGLISDGVTEITSIEHIDRGYPHIEEKFRMLGADIVRK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_XYLFA
Sequence: MNGFAVIPSVTTTTTSGEPIAGDVARKQNLLELNREGLERFFENVLGEKRYRAHQVMKWIHHRYVSDFEQMTDVGKALRARLQACAEVRVPCVVFDKHSADGTHKWLLAMDTDSKNAIETVYIPDKGRGTLCVSSQIGCGLNCTFCSTATQGFNRNLTTAEIIGQVWVAARHLGNVPHQQRRLTNVVMMGMGEPLMNFDNVVRAMSVMRDDLGYGLSNKRVTLSTSGLVPMIDRLSTESDVSLAVSLHAPNDKLREQLVPLNKKYPIAELMASCERYLSVNRKRDSVTFEYTLMKGVNDKQEHAHELVKLMRQFDCAMQVKGAAKVNLIPFNPFPGTYYERSTEVDIRAFQKILLDAQILAMVRRTRGDDIDAACGQLKGQVVDRTRRQAEFRRTIEDRVGRDVAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.