PharMolix/UniProtQA huggingface dataset:
Protein: ARO9_YEAST
Sequence: MTAGSAPPVDYTSLKKNFQPFLSRRVENRSLKSFWDASDISDDVIELAGGMPNERFFPIESMDLKISKVPFNDNPKWHNSFTTAHLDLGSPSELPIARSFQYAETKGLPPLLHFVKDFVSRINRPAFSDETESNWDVILSGGSNDSMFKVFETICDESTTVMIEEFTFTPAMSNVEATGAKVIPIKMNLTFDRESQGIDVEYLTQLLDNWSTGPYKDLNKPRVLYTIATGQNPTGMSVPQWKREKIYQLAQRHDFLIVEDDPYGYLYFPSYNPQEPLENPYHSSDLTTERYLNDFLMKSFLTLDTDARVIRLETFSKIFAPGLRLSFIVANKFLLQKILDLADITTRAPSGTSQAIVYSTIKAMAESNLSSSLSMKEAMFEGWIRWIMQIASKYNHRKNLTLKALYETESYQAGQFTVMEPSAGMFIIIKINWGNFDRPDDLPQQMDILDKFLLKNGVKVVLGYKMAVCPNYSKQNSDFLRLTIAYARDDDQLIEASKRIGSGIKEFFDNYKS
What is the function of this protein?
General aromatic amino acid transaminase involved in several otherwise unrelated metabolic pathways.  Mainly involved in tryptophan degradation.  Active with phenylalanine, tyrosine and tryptophan as amino donors and with phenylpyruvate, hydroxyphenylpyruvate and pyruvate as amino acceptors.  Does not accept glutamate or 2-oxoglutarate as substrates.  Also active with methionine, leucine, glutamine and kynurenine.  Catalyzes the formation of methionine from 2-keto-4-methylthiobutyrate (KMTB) in the methionine salvage pathway primarily using aromatic amino acids (tyrosine, phenylalanine and tryptophan) as the amino donors.  Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA) with pyruvate as amino acceptor.
What are the official names of this protein?
Aromatic amino acid aminotransferase 2, Aromatic amino acid aminotransferase II, Aromatic amino acid-requiring protein 9, Kynurenine aminotransferase I, KAT I.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_TRIV2
Sequence: MTEPVTQPALVIPQLIVGLGNPEPKYDQTRHNIGFAAVDALARAWNISLAENRKFQGQYGEGTAPGGVKIRLLKPLTYMNRSGQAIQAVTSWYKLSGESVLVIYDDLDLPLGKTRLRLSGSAGGHNGMKSAIAHLSTQNFPRLRIGIGKPKNAVNGDNSETVSHVLGKFSATETQLMSLVLQFVVECVELSLKQGVEKAMNRCNSYTVEAPKS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_CLOPE
Sequence: MSKPIVAMVGRPNVGKSTLFNKLAGKRISIVQDTPGVTRDRVYAESEWLNRKFTMIDTGGIEPESSDIIVKQMRRQAQIAIEMADVIVFVVDGKEGLTAADQEVAQMLRKSKKPVVLVVNKIDRLALEENSYEFYNLGIGDPITISASQGLGLGDMLDEVVKYFNDPSEDEEDDEYIRIAMIGKPNVGKSSLINRLLGEERVIVSNVPGTTRDSIDSYLETEDGKFILVDTAGLRRKSKVKEEIERYSVIRTYAAIEKADVAILVIDAEQGITEQDEKIIGYAHEMNKAIMVVVNKWDLIEKDDKTLSNYQKDLQQKLKFMPYAKYLFISALTGQRVHKILSTAKYCYDNYSKRVSTGLLNDVISKAVLMKEPPVVALKRLKIYYATQVATKPPKFVFFVNDPNLLHFSYGRYLENQLRESFDFDGTGIEIEYRARKE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CETP_MESAU
Sequence: NVISNIMADFVQTRAASIISDRDVEVDISLTRSPVITATHLESHHKGHFVYKNISEDLPLPAFSPTLLGDTRMLYFWFSEQVLDSLAKVAFQDGRLQLSLAEAEFRAVLETWHFNPNQEIIPELFSASLTSPGRVTVHCPGRPTISCQNKGVVVSSPVVIEFLFPHKDGQDSVTHTFEEDIVTTIQASYSKKKLFLSLSDFQIKPKMASNMDEDSASIQSFLQLMITTVGIPEVMSRLEVALTTLINSKGLDLFDIINPEIISRDGFLLLQMDFGFPEHLLVDFLQSLN
What is the function of this protein?
Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles.  Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.  Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination.
What are the official names of this protein?
Cholesteryl ester transfer protein, Lipid transfer protein I.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: RL27_ACICJ
Sequence: MAHKKAGGSSRNGRDSEGRRLGVKKFGDEQVIAGNIIIRQRGTKVKPGANVGVGRDHTIFALVDGRVKFSRKAEGRVHVSVEPLPLAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SSB_VIBCH
Sequence: MASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTLYGKLAEVAGEYLRKGSQVYIEGQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQGGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYSQPQYNEPPMDFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: G1PDH_META3
Sequence: MITTPRYIVIEENGINLLNDILLKLNLKNPLVITGKRTKKYISNFDYFYYFDYIDIKRNEPNKEFIENICNFDCIIGVGGGKAIDVGKYIAYKYNKQFISIPTTASNDGIASPIISQQGKSITAESPIAIIADLNIIKKSPKRLLSAGMGDIVSNITAVLDWKLSYKETKEPYSESSAIFSKTIAMELVEFVLSNDKNNLEEYPKKLVKALIGSGITISIAGSTRPASGSEHLFSHSLDIITKKLNLNINGIHGEQCGIGTIISAYLHLIEGNITIGEYENIKLSLEKVGAPTIGEQLGYDKNILIDALANAHKIRNRWTILRNGISKEKAEKILKKTDII
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAMP3_MACFA
Sequence: MSTGPTAAPGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLLIFIIIIIVWVVSS
What is the function of this protein?
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
What are the official names of this protein?
Vesicle-associated membrane protein 3, VAMP-3, Synaptobrevin-3.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type I membrane protein. Synapse, synaptosome.
Protein: LYSK_SULIA
Sequence: MQQEKELVKQKAKELLLDLLSIYTPSKNETNATKFFEKISNEFNLKLEILPDSNSFILGEGEILLASHVDTVPGYIEPKIENEVIYGRGAVDAKGPLISMIIAAWLLNEKGIKVMVSGLADEESTSIGAKELTLKNFNFKHIIVGEPSNGTDIVVEYRGSIQLDIMCESTPEHSSSAKSNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHFDVRYAINNKRDDLINEIKDKFQECGLKIVDETPPVKVSINNPVVKSLTRALLKQNIKPRLVRKAGTSDMNILQKITTSIATYGPGNSMLEHTNQEKITFDEIYIGVKTYMLAIEELWQKS
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
[LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRFA_POLPE
Sequence: MNLITLLVLGVSTCLIYGIEADEKTSSALENEIVEILNGNFKNEKKSIETSDQWLKGRFGREVNQWLKGRFGRELSDQWLKGRFGRELSDQWLKGRFGREVLDQWLKGRFGRDASNQWLKGRFGRELSDQWLKGRFGREGSNQWLKGRFGREASKNDLEKQNGRGDSDQWLKGRFGREARKQLLGGRFGRKDMNQLLAERHGRETSDQWLKGRFGRQLSDQWLKGRFGREVKNDKNNPFRSRYTGDSTQLQRENNQPIEELRDNTEKVSIENKPIMKKTSVKISKTV
What is the function of this protein?
Has direct action on motoneurons, and effect includes transient inhibition followed by prolonged excitation.
What are the official names of this protein?
Pol-RFamide neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CIPB_ACETH
Sequence: DPSKSFDSAIYPDRKMIVFLFAEDSGRGTYAITQDGVFATIVATVKSAAAAPITLLEVGAFRDNDLVEISTTFVAGGVNLGSSVPTTQPNVPSDGVVVEIGKVTGSVGTTVEIPVYFRGVPSKGIANCDFVFRYDPNVLEIIGIDPRSIIVDPNPTKSFDTAIYADRKIIVFLFCGRQRNRSVSITKDGVFAKIRATVKSSAPAYITFDEVGGFADNDLVEQKVSFIDGGVNVGNATPTKGATPTNTATPTKSATATPPGHSVPTNTPTNTPANTPVSGNLKVEFYNSNPSDTTNSINPQFKVTNTGSSAIDLSKLTLRYYYTVDGQKDQTFWCDHAAIIGSNGSYNGITSNVKGTFVKMSSSTNNADTYLEISFTGGTLEPGAHVQIQGRFAKNDWSNYTQSNDYSFKSRSQFVEWDQVTAYLNGVLVWGKEPGGSVVPSTQPVTTPPATTKPPATTIPPSDDPNAIKIKVDTVNAKPGDTVNIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIKPGELIVDPNPDKSFDTAVYPDRKMIVFLFAEDSGTGAYAITEDGVFATIVAKVKEGAPEGFSAIEISEFGAFADNDLVEVETDLINGGVLVTNKPVIEGYKVSGYILPDFSFDATVAPLVKAGFKVEIVGTELYAVTDANGYFEITGVPANASGYTLKISRATYLDRVIANVVVTGDTSVSTSQAPIMMWVGDIVKDNSINLLDVAEVIRCFNATKGSANYVEELDINRNGAINMQDIMIVHKHFGATSSDYDAQ
What is the function of this protein?
Acts as a scaffolding protein in the cellulosome.  It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes probably through the binding of the nine repeated domains with dockerin domains present in catalytic subunits of the cellulosome.
What are the official names of this protein?
Cellulosomal-scaffolding protein B, Cellulose-integrating protein B, Cellulosomal glycoprotein S1/SL.
What are the subcellular locations of this protein?
Secreted. Note=Remains at cell surface.
Protein: MSCL_PSESM
Sequence: MSVLTEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPLGLLIGGVDFSDLAVTLRPAQGTAPAVLLAYGKFIQTVIDFIIVAFAIFMGVKAINRLKREEAKAPTLPPTPSKQEVLLSEIRDLLKAQNTPAAPITVDPARTL
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOZ_PSEE4
Sequence: MARVTVEDCLEHVDNRFELVMLSTKRARQLATGGKEPRVAWENDKPTVVALREIAEGIVTPEFIAAEEIVTEDPVFAAFEDENNEAV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: FADR_ECOLI
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism (PubMed:1569108, PubMed:8446033, PubMed:9388199, PubMed:11859088, PubMed:19854834, PubMed:21276098).  Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE (PubMed:9388199).  Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the glyoxylate shunt enzymes (PubMed:9388199).
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPPD_NEUCR
Sequence: MSPSAISSEYSNCNGTPDYALQSSEVSNFNGYDHVTWWVGNAKQAASYYNTVFGFKTLAYRGLETGSRYFASYVVGNADVRFVFTSPIRSQKCLPEEEPISDADRKLLQECHEHLEKHGDAVKDVAFEVDNVDGVFHKAVAAGADVVQEPTTLTDKMHGSVRTAVIRTYGDTTHTLISRADYNGPFLPGFRTAAPSSATVQLPSVPLARIDHCVGNQDWNEMVSACAFYEQCLSFHRFWSVDDSQICTEFSALNSIVMASENNLVKMPINEPAPGKKKSQIEEYVVFNSGAGVQHIALLTPDIISTVSAMRARGVEFINVPSTYYDTIRQRLKTEKRGWELKEDLDTIQKLNILIDYDEGGYLLQLFTKPLMDRPTVFIEIIQRNNFEGFGAGNFKSLFEAIEREQAERGNL
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
Protein: SPSS_METM5
Sequence: MEINTDKYKNITRNLEREMINLNPIQRGGILPTESKKIIYEYWDGYSVCDYCSGRLDRIETPPINEFLEDMSKFLGMDITRPTHGARESKYAVMNSICKEGDYVVLDGNAHYTSYVAIERAKLNYEKTDIGEYPTFRVIPESYAEKIDMLEDSKKNIGLILLTHVDGNYGNVADVEKVGKIAKSKGYPFLLNCAYSAGRMPIDGKKLNVDFIAASGHKSMAASGPCGLLSINKKYEDEVLETSKVNVVKELQMLGCTSRGIPILSLMASFERLIERVKKWDLELEKTRKVVNELEPLGFKQIGEKPRNHDIIRFETPILDEIAEKDKRRGFFFYEELKRRGLGGIRRGVTKEFKMSVYGLTNTQVDYVINSMKTIINELR
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: MRAZ_STRM5
Sequence: MFQGETAITVDDKGRMAVPTAYRDLVARASNNRLVLTYNPFEAGCLWLYAESEWERVRDDVMSKPNTQRVVRLLQQKLVGSAAHLELDGNGRISIPASHRGAVGIEKKAVLLGMGDKFELWSEQAHRALIQQTLSDEDLGDGLLDLKL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AROB_MYCTO
Sequence: MTDIGAPVTVQVAVDPPYPVVIGTGLLDELEDLLADRHKVAVVHQPGLAETAEEIRKRLAGKGVDAHRIEIPDAEAGKDLPVVGFIWEVLGRIGIGRKDALVSLGGGAATDVAGFAAATWLRGVSIVHLPTTLLGMVDAAVGGKTGINTDAGKNLVGAFHQPLAVLVDLATLQTLPRDEMICGMAEVVKAGFIADPVILDLIEADPQAALDPAGDVLPELIRRAITVKAEVVAADEKESELREILNYGHTLGHAIERRERYRWRHGAAVSVGLVFAAELARLAGRLDDATAQRHRTILSSLGLPVSYDPDALPQLLEIMAGDKKTRAGVLRFVVLDGLAKPGRMVGPDPGLLVTAYAGVCAP
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RHIME
Sequence: MTRKQKRLAIIGGGVAFLTAAVLLVMFAFSQAVAYFYVPGDLAKADVAPGTRIRLGGLVEAGSVKRGEGRTITFTVTDTLATVPVTYTGILPDLFREGQGVVAEGAFVGGSPVFVADTVLAKHDETYMPKDVADRLKAQGVTLGGEENIR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RS8_BRUA1
Sequence: MSVSDPLGDMLTRIRNAVGRKKTKVSTPASKLRARVLDVLQAEGYIRAYTQSEFENGKAEIEIELKYYEGVPVIREITRVSKPGRRVYVSVKSIPQVANGLGISILSTPKGVMADHEAREQNVGGELLCRIF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ARA1_MAGO7
Sequence: MLLFTKLAAPKAPKRRSRAGCTSCKERKKKCNEERPQCSRCAERGSSCVYEPVRPRQRRKRDSFITSLADASTNGSHQHEAEEDDHGARFDRFDACEDHLSQHQRVSHDWGHQPWQASMPDSFDDDLIFSPLDDTFDPNVLLAAAPLETSSVIINPDEDFTGPLSSTTQPRVLRYEEDDDDGEEEIDIGGGGAGLIGIKHDRRSSFTSTTTVATNTTAGNTIFSTDLTICSPATVRSPLLEFTCPSFSEFSENPRQRSLVDHFCNVLSHLIVFREETGNPFQQLVLPLMRGGGGGGNNSPVADAVFALAGAHLEHRGVDVKGGEKSLYFHHRAIQGLAGLIRMHNAGVNRNEVLAAIMLLIYYEVLVQRGRSNIVEGHLKGALTVMCSNPEPLDSTGIFLERAFRFYDVIAALSFGTAPLSTAPAAGCLVPFPISAPTATSTLNNVDSLLGMATTLWPIIHRLSALLPLKTDVANARDAGHNGKVAVLRTEFETTVGAVEAALLGWTPNLPTGWVLHESDPTKLVEDTTAAKDENSTGEEKRSGGDSARLHSILNNALAYRNSALVYLYRTVLSHPRDHPLVQRHANLSLRHCAATVEHQGPMGALLWPLFVAACEAVTGADRDTARTAFAAIDKRQGMTNIERAWDIVQEVWRRAEGGTEETVRGEGVRSDTSPAQLSMACSRELKGTADMWRVVSKEMGVNIVFG
What is the function of this protein?
Transcriptional activator of the arabinanolytic system.  Involved in the regulation of extracellular arabinanolytic genes and in the regulation of the intracellular activities of L-arabinose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of L-arabinose.
What are the official names of this protein?
L-arabinose-responsive transcription regulator ARA1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_AZOSB
Sequence: MLAKRIIPCLDVSAGRVVKGVNFVDLRDAGDPVEVARRYDAQGADEITFLDITASSDDRDIILHVVERVAEQVFIPLTVGGGVRSVEDVRRLLNAGADKVSINTAAVNNPSIVAEASGKVGSQCIVVAVDAKQTGPGKWEVFTHGGRNPTGLDAIEWARKVESLGAGEILLTSMDRDGTKIGFDLGLTRAVSDAVGIPVIASGGVGSLEHLADGVSEGRADAVLAASIFHFGQHTVREAKELMRTRGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRA_CLOTE
Sequence: MRDKIVVKGAKVHNLKNVDLQIPRDKFVVFTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGQMDKPDVEYIEGLSPAISIDQKTTSKNPRSTVGTVTEIYDYLRLLYARVGKPHCPKCGKEIQQQTVDQMIDKILELPERTRIQVLAPIIKGRKGEHIKVIENIIKGGYVRARIDGEIIDLQEESVKLEKNKKHTIEAVIDRIIIKSDIRSRLADSIEIALKLSEGVVIINVIDKEDILFSENFACIDCGISIDEISPRLFSFNSPFGKCDYCDGLGTLLEIDEKLVIPNKSKSILEGGILPWANTVTNEDSWTFSILKALSKKYNFSLNTPIGELDEEIYNMLLYGIKGERIKVRYKKDGRAVDFNHTFEGLMNTLKRRYMETNSNYMKDNIENYMSDNFCPKCKGARLKPEALAVTLGEKNIFEFCKMSIREELRFLSELMLSNKNKIISNQILKEIESRLQFLIDVGLDYLDLARMAGTLSGGEAQRIRLATQIGSSLVGVLYILDEPSIGLHQRDNDRLIATLKRLRDLGNTLIVVEHDEDTMRAADYIVDIGPGAGEHGGEIVAAGDLKTVMETEGSLTGQYLVGKKKIDIPINRRKSNGKSIIVKEAKENNLKNVDVEFPLGTFTCITGVSGSGKSTLINEILYKGLNKKLNNSKEHPGLHKEILGIENIDKIINIDQSPIGRTPRSNPATYTGVFDGIREVFSNTTESKMRGYKPGRFSFNVKGGRCEACKGDGIIKIEMQFLSDVYVPCEICKGKRYNRETLEVKYKNKNISEILDMTVEESVDFFKNIPKIKNKLQTLMDVGLGYVRLGQPSTQLSGGEAQRIKLASELSKRSTGKTLYILDEPTTGLHIDDVNRLISIIQRLVDGGNTAIIIEHNLDVIKSADYIIDLGPEGGAKGGEVIGIGTPEEISVNIDSYTGHYLKKML
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_JANSC
Sequence: MNVHVKTADQTPSTVQAQDALAILSAWASEASADQIDALDPGIARLVRVQAYPDLRAEYPGDFTVDEAYRATLPDLQNGPASLIKGANRRIQHVGISNFRLPIRYAVQDGSEVMLETSVTGTVSLEADQKGINMSRIMRSFYKHADASFGFDVIEAALDDYKADLGSFDARIQMRLSYPMKVDSLRSGLSGWQYYDIALELVERGGVRQRIVHLDYVYSSTCPCSLELSEHARATRGQLATPHSQRSVARISVELQGQGVWFEDLIEMARSGVPTETQVMVKREDEQAFAELNAANPIFVEDAARLFAEQLQAHSGVGDFRVMASHQESLHSHDAVSLLTEGDTFAEVSLDPKLFPSLIHVG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: CBL_MYCLE
Sequence: MTSNPLEQLTIEQLQCRTSMKWRAHPEDVLPLWVAEMDVLLAPTVAEAVHRAVDNGDTGYPYGTTFAEAISEFASQRWQWHDLDVSRTAIVPDVMLGVVEMLRLITDRGDGVIVSPPVYPPFYAFVTHDGRRVLEAPLGRDGRLDLAALQDAFSRARRSSGPNGKVAYLLCNPHNPTGSVHTVAELHGVAELARRFGVRVISDEIHAPLVLSGARFTPYLSIPGAENAFALMSATKGWNLCGLKAAIAIAGREAAADLRRIPKEVSHGPSHLGIIAHTAAFRTGSSWLDALLQGLEANRALLRDLVTKHLPGVRYQRPQGTYLTWLDCRHLGFDEQINEGLAAISDLSGPARWFLDHSRVALTSGHAFGTGGVGHVRVNFATSQAILIEALSRMGRALVNFR
What are the official names of this protein?
Putative cystathionine beta-lyase, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
Protein: RUVA_CHLPD
Sequence: MFAYFKGSLVTALPEEAVIDVSGVAYRMLISATTFRQLPDEGSQVLLYAHLSVREDALQLYGFFKEEERQLFRLLLLTSGVGPKLALAVLSGLQVPEVHEAIMANEPERLYGVSGVGKKTAARIILELRDKILKLPLVTPAAGKAAMPSHHVKDDAVHALVTLGFSRLLAQKAVSALLEEKPEQSVEEVIKYALATIHNS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PRMA_STRA1
Sequence: MNTWNELTVHVNREAEEAVSNLLIETGSQGVAISDSADYLGQEDRFGELYPEVEQSDMIAITAYYPDTLDIEVVKADLADRLANFEGFGLATGSVNLDSQELVEEDWADNWKKYYEPARITHDLTIVPSWTDYEAKAGEKIIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKDIYAFDLDVVAVRVAQENIDMNPGTDNIHVAAGDLLKGVQQEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIISEKWDMVRESAEKAGFFLETHMVQGEWNACVFKKTDDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_CLOK1
Sequence: MEFEAVIGLEVHVELLTETKIYCGCSTAFGSEPNKHVCPVCLGLPGSLPRLNKKVVEYAIKAGLALNCSINNKSRMDRKNYFYADCPKNYQITQQEIPICREGFIEIRNHLGEKKRIGIERIHMEEDAGKLIHTDEGTLIDYNRAGIPLIEIVSKPDIRTSKEAVSYLEDLRNILKFIGVSDCKMEQGSLRCDCNISIRPKHNLKLGVKTEIKNMNSFKALEKAIQYEYKRQSDLIESGEKVRQETRRWNDAKNVTEVMRSKEYANDYRYFPEGDLTAINISDNYIDNIRKTIPELPDKKIDRFVEEFKISRKEIEILILNMEIGDFFENAAKLSGDPKSVSNWITGDISRLAKETGIPLNNLNFTERDLAELIEFINCGVISNNIGKKVIEEMFYKGKSPRQIIHEKGFVQNSSKEKILKVVKEVMEENPKSIEDYKKGKKKAVKFMIGMVMKKTKGNANPMLVNKLVEEEIGKY
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.