PharMolix/UniProtQA huggingface dataset:
Protein: PURP_METKA
Sequence: MLSREEILEILSEYDLEDLSIATLGSHTALHILKGAKEEGLRSVVVCEEGRTTPYERLGVADEIIVVERFQDMLDEEVQERLRELNAIVVPHGSFVAYVGLDGIENEFCVPMFGNRRLLRWESERSLERKLLKRAGVKVPKVFDSPEDIDRPVIVKFPGARGGRGYFICSDPEEFEEKAERLIEDGVIDEEDLEQAHIEEYVVGTNFCVHYFRSVVEDTVEVLGMDRRYETNIDGLVRMPAGDQLEAGLEPSYVISGNIPVVVRESLLVQLYEMGDRVVRASEDIEEPGFIGPFCLQTLCTEDLEFYVFELSARIDGGTNVTFLPYAYLKFGEIVTMGRRIAKEVREARDKGLLEGVVT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MUTS2_CLOTE
Sequence: MNERALKVLEFYKIKEKLKGFVKTNAAKDIVDNLKPYTNLYEVEMHLEETMEALDLLQTKGEPPFEGVYDIRDILIRVEKAMVLLPGQLLKVASILKSSRRFKDYVGRKHEETPHKNIEDICEGIELLKGLEESIFNIVISDDEIADRASLKLYGIRRSLRDKNDSLRDRVNSLVRKYSPYLQESIYTIRGDRYVLPVRAEHKGSVPGLVHDQSSSGATLFIEPMSLVNLNNEIKELLLKEREEIERILEELSLKVYNNLDVVNVNAKVIWELDFIFAKAKFASHNNCTLPKVSEDGIVDIIEGKHPLIDTEKVVPTDIYLGKDFTSLIITGPNTGGKTVTLKTLGLIHIMGLSGLLIPAKENSTIAFFEEIFADIGDEQSIEQSLSTFSSHMVNIVDIISKADHKSLVLFDELGAGTDPTEGAALAISILENLRRRKCKIVATTHYSELKGYALKTEDVENASVEFDVETLRPTYRLLIGIPGKSNAFEISKRLGLGEDIIEEAKNNIESDSLKFEALIEKLQSKSIKASDDARRAEMYKLEADRLKDKYEDKLKIVEETREKLLKGAQEEAKKLIKEAKEEADEILKNIRELEKMGYSSTARQKLEEERKKLNSKIHKLEEKEENLNKEKGKKIKEINLGEEVYLPKLDQKVIILSKPDNRGEVQVQAGIMKINVKLDDLRLVDKPKEENKKGRKREAKLRMRTVESEIDLRGMDSMEAVYNTDKYLDEAYVAGLKEVTVIHGKGTGILRKSINDMLKRHPQVKNYRLGEYGEGGTGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: O17D_CONMA
Sequence: STRCQGRGASCRKTMYNCCSGSCNRGRCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This toxin blocks channels of the N-type as well as other types.
What are the official names of this protein?
Omega-conotoxin MVIID, SNX-238.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISCA_SHIBS
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: BEST3_MOUSE
Sequence: MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGAQKRYFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMLLISSSVHGSDQHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTADERKLFDHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVVTLAVYTFFFACLIGRQFLDPTKGYVGHDLDLYVPIFTLLQFFFYAGWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPPYTLAAADYCIPSFLGSTIQMGLSGSNFPAEDWLWNYEKHGNRHSVMRRVKRFLSTHEHPGSPRRRRSFGRQASDSSMFLPPSPARDLLDVPSRNPHRGSPTRKQSRSQEGSPKLHSSMGELSTIRETSRTSTLQSLSPQSSVRSSPTKMPQVPEVLITAAEAPAFSADSHQHDSTTSILSLEFTGVQPSGTEQQVEPSGTPPGDPNPQTTSASTERDLFKFEEDLEDDRFPKRWSLPEFLESRHTSLGNLGPDPVSPRDALLLPDTETPSETNGIHPGAGSALAPDILYLMESLDKETDILEFNNEHTGESPKGTPQRPRTWF
What is the function of this protein?
Forms calcium-sensitive chloride channels.  Permeable to bicarbonate (By similarity).
What are the official names of this protein?
Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABZ_ECO24
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIPS_BACTN
Sequence: MNYRDYLQQLIYKIINPLIHGMIKIGITPNFITTTGFILNVVAAGMFVYAGICGGQNDLSILGWAGGVILFAGLFDMMDGRVARLGNMSSKFGALYDSVLDRYSELMTFFGICYYLSVKDYFIYAIIAFVALIGSLMVSYVRARAEGLGIECKVGFMQRPERVVLTSLGALFCGVFKDITAFDPMLILMVPLTIVAVFANITAFARVRHCYKVMTANEKKND
What is the function of this protein?
Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP (PubMed:35080445).  PIP is a precursor of phosphatidylinositol (PI) (PubMed:35080445).
What are the official names of this protein?
Phosphatidylinositol phosphate synthase, PIP synthase, PIPS.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Protein: M2_I83A6
Sequence: MSLLTEVETLTRNGWECKCSDSSDPLIIAASIIGILHLILWIFNRLFFKCIYRRLKYGLKRGPSTEGAPESMREEYRQEQQSAVDVDDVHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: ACP_RHOPA
Sequence: MSEIGERVKKIVVEHLGVEPEKVVDSASFIDDLGADSLDTVELVMAFEEEFGCEIPDDAAETILTVGDATKFLEKNAKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_CLOPE
Sequence: MVNQLEMLYEGKAKKIYATDKEDMVIVHYKDDATAFNGEKKAQIESKGVLNNEITSLIFEMLNKEGIKTHFVEKLNDRDQLCKKVEIVPLEVIVRNVAAGSMAKRLGLEEGYELKTTVFELSYKDDSLGDPLINDYHAVGIGATTFEELNKIYEITAKVNEILKEAFKKQNINLIDFKLEFGRYNGEILLADEISPDTCRFWDATTGEKMDKDRFRRDMGNVINGYREVLNRLRN
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: HSLO_THEM4
Sequence: MVINGIAYKALVRFSVIDSTDLVKTATKKHNLSPITSVALGRLLTGIALMVPWLSKNDTLTYIIEGSNKIKYIAAQSKNNGNVRGYILPKIVDTITNEKGKFDLKSAIGNGTLKVVRDLGLKTPYVTPIKLISGEIAEDLTYYFTISEQIPSAIALGVLVDKNGIKRAGGIIIQILDQSLPKKDITEIEKKFKEITPITNFLEKHTPIDALKHIFGKKIEKTETHEINFRCSCSHQKALESLKLLKVDELKEIIIKNEIVEVSCKWCSTTYKIKPEEVKKILEEKNK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMD2_YEAST
Sequence: MSSQIIDRPKHELSRAELEELEEFEFKHGPMSLINDAMVTRTPVIISLRNNHKIIARVKAFDRHCNMVLENVKELWTEKKGKNVINRERFISKLFLRGDSVIVVLKTPVE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: TOP1B_ARATH
Sequence: MATEAFVKPVVPNGHDGYEDEDEDDIPLVFKRNSNTAATTNRPSPINNAMRNSAIGSTKSSPPMRSPLTSPNRSASSSTRSSMMKPALPSSSSVQRSTLKSPLRDDRSVVAKERNGFGKAPSVSKSDDEDSEDDKPLSARLKLDSKEVTKQPSSSGRGSTQQAVQKSNMRPQGLSDYTKKKVLDERAPMSSTVQTKTSVGTSSSKPVHIEQKRPLVNNIDRNGLKPKTEGHSSQAPAKRPLEKGSSSNQSSVKRPKLSEPARPVKVEQGSHISATQDAKGKNLDASKPLRANQATVKEDNSDGDDHVPIASRMKSDSSNNKSSSAKPSSSKMIASSSRTIAQKPNKWVKDSKYSKSSKSLPSGDGQKKWKTLQHNGVIFPPPYKRHGVKILFQGKPVDLTPEQEEVATMFAVMRETEYYKKPKFRENFWNDWRKLLGKNHMIKSLDDCDFTPIYEWYMQEKETKKQMTAEEKRIVKEEKLKQEEKYMWAVLDGVRERIGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKEAPIPECPIPGERWKEVKHDNTVTWLAFWSDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLHNHIGSIRAAYTKDFNNKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVEPLVYKAIGQFQAGKSKTDDLFDELDTSKLNTHLKELMAGLTAKVFRTYNASITLDLMLSKETRDGDVPEKVVVYQQANKEVAIICNHQRTVSKSHGAQVEKLAVKIEELREQIKELNIDLDRAKKGRTPLMGSDGKRKRNLTPEALEKKIMQTQGKIEKMERDMQTKEDMKTVALGTSKINYMDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMDVDPEFRFCSSTDE
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).  Topoisomerases 1 enzymes (TOP1A and TOP1B) are essential for plant survival (PubMed:12215507).
What are the official names of this protein?
DNA topoisomerase 1 beta, DNA topoisomerase 1.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIPI3_CAEEL
Sequence: MARTKCKTKTVANPRTGVRKTAKDLSEPVRQDAVSRRRPTTLPFVGNTSSRPRVFYDVLAKKNVVFPNVKAEYHYRVRNAPKIDPKNFGTTLPICYSSIGPAKTLELRPLGRLPPHIIKALNDHYVQLTRGSMVPAADLYNNGDHPAEQRIPTMLNENEYLRLIQELEEEEKSKQFSATSSSAPHVNPYSAQHLVNGEIIGIFVIYGTGLVTRAVCSQTREMFTAHVLPEWKASKVIDVIRRLQIPTDISSMTADEIRLSELCISKRMEIIKSNDRYILMNPCESATIHSYATERLDEITENDVMSIYQKVVEIVRFCHSRKVILQNFKPRSFYLKKDAHNKWVVRPCFLQDMSCEEDQSEAQFTRRSVCVPFMAPEMLTAESRTHHSYSTELWGLGVLLYILLTGKYPFHENSMPLLFRTIKFKQHRWPFNFISSKSRNIVNMLLKKAPATRMNLEDLWNQVNGDFPEIRCRSNIILKKQDMIVKMDLFEMYYNTYKDRLLPKNVLPMYEEMKACRNDSTILTEMAKRDFRSIQEQMKRRIETKPTEYQTLVMQVRLQQINQLFFEKEVSQAQKQHRAPRLVQLKCSDISKELLLPGDIYPISEHYHPSQQPVDKVVYKLLSDANSLAFPTVMKGTVPKSYPPPVFKGLDISPS
What is the function of this protein?
Adapter protein that regulates different signaling pathways (By similarity).  Required for larval development and viability (PubMed:27927209).  Involved in negatively modulating pmk-1 p38/MAPK signaling (PubMed:27927209).  Involved in innate immunity, acting either in a manner dependent upon, or independent of, the pmk-1 or pmk-3 p38/MAPK pathways (PubMed:18394898, PubMed:27927200, PubMed:34407394).  Has a protective role in response to infection by the Gram-negative bacterium P. aeruginosa, acting by negatively modulating expression of cebp-1, and regulating the pmk-1 p38/MAPK pathway, leading to activation of transcription factor skn-1 (PubMed:27927200, PubMed:34407394).  Required to prevent P. aeruginosa toxin ToxA-mediated lethality, probably acting via modulating the effects of translational inhibition caused by the toxin (PubMed:27927200).  By regulating the up-regulation in the epidermis of antimicrobial peptides nlp-29 and nlp-31, plays a role in resistance to fungal infection (PubMed:18394898, PubMed:27927200).
What are the official names of this protein?
Protein nipi-3, No induction of peptide after drechmeria infection protein 3, Tribbles homolog nipi-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2910_MYCTU
Sequence: MCAVLDRSMLSVAEISDRLEIQQLLVDYSSAIDQRRFDDLDRVFTPDAYIDYRALGGIDGRYPKIKQWLSQVLGNFPVYAHMLGNFSVRVDGDTASSRVICFNPMVFAGDRQQVLFCGLWYDDDFVRTPDGWRIIRRVETKCFQKMM
What are the official names of this protein?
Uncharacterized protein Rv2910c.
Protein: RLMD_ERWT9
Sequence: MAQFYSAKRRVTTRQTITVKVHDLDSFGQGVAHHNGKALFVQGALPDEVAEVSIIEDKRHFSRGVATRIVTASPQRVEPRCPHYSRCGGCQQQHASPTLQQESKAKALSRLLSKPRGETVEVDDIIASRPWGYRRRARLGLSFQPKSQTLHMGFREKSSSELVNISQCPILKPELNALLQPLHAVLSSLQAVRRLGHVELVQADSGSLLVLRHLDALTAEDRQKLERFSHQYRLSLFLAAESDTLEQVSGGMPHYQSHDLTLTFSPRDFIQVNDDVNQQMVARALAWLDLQPEDRVLDLFCGMGNFTLPMGKFAKNVVGVEGVAALVAKAGYNAELNCLNNVAFWQHNLEEDVSRQPWAVEGFNKVLLDPARAGAAGVMAHIIKIAPQRVVYVSCNPTTLARDSEILLTSGYQLERVTMLDMFPHTGHLESMVLFSRK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: YUC10_ARATH
Sequence: METVVVIVGAGPAGLATSVCLNQHSIPNVILEKEDIYASLWKKRAYDRLKLHLAKEFCQLPFMPHGREVPTFMSKELFVNYLDAYVARFDINPRYNRTVKSSTFDESNNKWRVVAENTVTGETEVYWSEFLVVATGENGDGNIPMVEGIDTFGGEIMHSSEYKSGRDFKDKNVLVVGGGNSGMEISFDLCNFGANTTILIRTPRHVVTKEVIHLGMTLLKYAPVAMVDTLVTTMAKILYGDLSKYGLFRPKQGPFATKLFTGKAPVIDVGTVEKIRDGEIQVINGGIGSINGKTLTFENGHKQDFDAIVFATGYKSSVCNWLEDYEYVMKKDGFPKAPMPKHWKGEKNLYCAGFSRKGIAGGAEDAMSVADDIRSILATLKNN
What is the function of this protein?
Involved in auxin biosynthesis.
What are the official names of this protein?
Probable indole-3-pyruvate monooxygenase YUCCA10, Flavin-containing monooxygenase YUCCA10.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: HXT11_YEAST
Sequence: MSGVNNTSANELSTTMSNSNSAVGAPSVKTEHGDSKNSLNLDANEPPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Hexose transporter HXT11, Low-affinity glucose transporter LGT3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MTAP_PHANO
Sequence: MLQRARLWPPIFTSRCAPFPFSRSISIPYRRMAGVPSTYDAPVHIAVIGGTGISSLPGFELAATLDVDTPWGKPSSPISILQHNSPTTGKPVPVAFLSRHGLHHEHAPHEVKNQANIAALRHIGVRTIIAFSAVGSLQEEVRPRDFVVPDQIIDRTKGIRPFTFFEKGMVGHVGFGDPFDKSLAEIVRKCGHSLEGEGVRLHDKGLLICMEGPQFSTRAESNLYRTWGGSVINMSALPEAKLAREAEISYQMICMATDYDCWRGDGSEDVNVEMVMAHMKANAENARRFVGAVLNELTKEEHGELVLAKHIEGQMRFAGAMTKKEGRGQDAEKKLQWLFPGYFD
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMP_CUPPJ
Sequence: MHLADLIETTLNGMGYELVELERAPAGLLRVYIDQPETGIVIEDCEKVSRQLTHVLTVENVDYERLEVSSPGLDRPLKKLADYVRFAGAEARVTLRLPVNGQKNFTGILREPTGEAGAEKVGLEFEGKDGPALLEFTVSDVDKARLVPVIDFKGNQRKGNKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM1H2_DEIAC
Sequence: FPYQGSSTILESGNVNDYEVVYPRKVTALPKGAVQQKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSEIHYSPDGRRITTHPLVEDHCYYRGHIRNDADSTASISACNGLKGHFKLRGETYLIEPMKISNSEAHAVYKYENVEKEDEAHKMCGVTQNWESYEPIKKASQLIVSTEFQRYMEIVIVVDHSMYTKYKGDSDKIKAWVYEMINTISESYRYLYIDIIVSALEMWSEKDLINVETSAENTLKSFGEWRAKDLIHRISHDNAQLLTATDFDGPTIGLAYVASMCDPKRSVGVVQDHSSVNHLVAITLAHEIAHNLGVHHDKSSCSCGSGYTCIMSPVINSEVIKYFSDCSYIQCREYISKENPPCILNKPLRTDTVSTPVSGNELLEAGKDYD
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Snake venom metalloproteinase H2, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYN_MYXXD
Sequence: MQVVSVKKALAGGVEEGTKVEVRGWVRTRRDSKAGISFVNVSDGSTFDPIQVVAPNSLPNYEKEILHLTAGCSVISRGTLVKSQGKGQAYEVQADEVQVLGFVDDPDTYPIQPKQHTLEFLRDVAHLRVRTNTFSAVTRVRHRAAQAVHRFFDEEGFFWVNTPIITASDAEGAGQMFRVSTLDAVNPPRTSDGKIDWHKDFFGKEAYLTVSGQLNAEAYALAMSKVYTFGPTFRAENSNTTRHLAEFWMIEPEVAFADLNEDANLAERFLKHVFKAVLNDCAPDLKFFEERVQKGVIERMEKFINSSFERIDYTEAVEILKKAKKKFEFEPEWGKDLQTEHERYLTEEHVGRPVVVMNYPEAIKSFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDQRIQKFGLKPESYQWYRDLRRYGSVPHAGFGLGFERLIVYMCGLQNIRDAIPYPRVPGSAAF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBP35_ASHGO
Sequence: MQTSAEMGGIIEAMPALAQDGYALEQAPPEHCPGPASENAGKGDACQGCANKDICESLPKGPDPDVALITQNLAPVRHKVLVLSGKGGVGKSTFSAMLGWALSADEALQVGVMDLDICGPSLPHMLGCVNETVHESSVGWTPVYVADNLAAMSIQFMLPEDDSAVIWRGAKKNALIKRFLKDVYWDELDYLVVDTPPGTSDEHITINTLLKESGIDGALVVTTPQEVALLDVRKELDFCRKAGIRVLGLVENMSGFVCPSCENESTIFKPTTGGGRALCEELGIKFLGAVPIDPRIGRCCDSGESFLDAYPDSPASTAIMHVVEALRDAVGDV
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NBP35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL17_MYCUA
Sequence: MPKPTKGPRLGGSSSHQKALLANLATSLFEHGRIKTTEPKARALRPYAEKLITHAKKGALHNRREVLKKIRDKDVVHTLFAEIGPFFADREGGYTRIIKVEPRKGDNAPMAVIELVREKTVTSEADRARRVKASQAASQDAPSEPQAAEEPAAEEAVAATEAEAAPADAEATDAEAGSADTDADEAPQN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MHPC_ECO24
Sequence: MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
What is the function of this protein?
Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
What are the official names of this protein?
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MhpC family.