PharMolix/UniProtQA huggingface dataset:
Protein: YAEH_SALTY
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAKSVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILDDLRHLESVVANKISEIEADLDKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: SCTN1_SALTY
Sequence: MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQVVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFASAGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDFPSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPASVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAGQGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENIDNDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN
What is the function of this protein?
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:15060043, PubMed:16208377, PubMed:26170413).  Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable).  Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (PubMed:8045880, PubMed:14762212, PubMed:15060043, PubMed:26170413).  May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (PubMed:16208377).  Releases the effector protein SptP from the chaperone SicP in an ATP-dependent manner (PubMed:16208377).
What are the official names of this protein?
SPI-1 type 3 secretion system ATPase, T3SS-1 ATPase, Invasion protein InvC.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane, presumably through interactions with other components of the SPI-1- encoded T3SS.
Protein: RL30_LATSS
Sequence: MAKLKITLRKSAAHRLPEQRKMVKEFGLNRVNSSVIKPDDAATRGVIFKLAHLVTVEEIKD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: REXO5_BOVIN
Sequence: MEPERKRSGSTLKKGRKRRLIPSKVVGAAEATRSHWDLEEKQQPIAKKARLSTVLFAENCEVTHGQLCELLKYAVLGKSSFPKPSWCQLFHQNHLKNVVVFILQGLSQLHFYKFYLEFGFLRKAFKHKFRMPPPSSDFLADIIGLQKKQIIGNLPKAMEGSLPFASSKVSINLQKDPIIQKYGFKKVGLTRCLLTKEEMKTYHFPLQGFLDCENFVPTKCNGSVTDNSPLFGLDCEMCLTSKGRELTRISLVAEGGGCVMDELVKPDNKIVDYLTSFSGITKKILNPVTTKLKDVQRRLKILLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKAILGKDIQCPDRLGHDATEDARTTLELARYFLKYGPKKIAELNLEALFSYQESQEPRNTAEGVQRLNTSVLECLDSVGQKLLFLTQEADASALSSSKNCQTIKCLSNKEVLEQARVEIPLFPFSIVQFSFEPFSPNLTQEMNKRIKIKWTEMSTVYAGPFNKNCNLSALKRLFKSFGPVQLMTLVLETHQPHLCIQYEVLEAAQLAIESLDGVLVEGSCIKVQRPVTELTLDCDTLVNELEQDSENRGTIYLSGVSETFKEHLLQHCSIFLGLEAMILPKDLKSGKQKGYCFLRFKTFGSAQRALNILTGKDWKLRGRHALTPRHLHAWLRGLARESRLPGVRVIPPPSEQEAWQMLNVDHPKIAAWHWGRKIEKLYHNLCPGTLCLILLPGTKSTHGSLSGLGLMGIKDEEESTIPQTCVCESAHHLPGVIS
What are the official names of this protein?
RNA exonuclease 5, Putative RNA exonuclease NEF-sp.
Protein: RL22_SACD2
Sequence: MEVAAKLRGAGMSAQKARLVADQIRGKSVEEALDLLTFSTKKGAALIKKVLESAVANAEHNEGADVDELKVSTIFVDEGLTMKRIRPRAKGRADRILKRTCHITVKVADQ
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AMT13_ARATH
Sequence: MSGAITCSAADLATLLGPNATAAADYICGQLGTVNNKFTDAAFAIDNTYLLFSAYLVFAMQLGFAMLCAGSVRAKNTMNIMLTNVLDAAAGGLFYYLFGYAFAFGGSSEGFIGRHNFALRDFPTPTADYSFFLYQWAFAIAAAGITSGSIAERTQFVAYLIYSSFLTGFVYPVVSHWFWSPDGWASPFRSADDRLFSTGAIDFAGSGVVHMVGGIAGLWGALIEGPRRGRFEKGGRAIALRGHSASLVVLGTFLLWFGWYGFNPGSFTKILVPYNSGSNYGQWSGIGRTAVNTTLSGCTAALTTLFGKRLLSGHWNVTDVCNGLLGGFAAITAGCSVVEPWAAIVCGFMASVVLIGCNKLAELVQYDDPLEAAQLHGGCGAWGLIFVGLFAKEKYLNEVYGATPGRPYGLFMGGGGKLLGAQLVQILVIVGWVSATMGTLFFILKRLNLLRISEQHEMQGMDMTRHGGFAYIYHDNDDESHRVDPGSPFPRSATPPRV
What is the function of this protein?
Ammonium transporter probably involved in ammonium uptake from the soil.  Contributes with AMT1-1 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions.
What are the official names of this protein?
Ammonium transporter 1 member 3, AtAMT1;3.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPC24_MOUSE
Sequence: MAAFRDMVEVSNWLLSLLGANRAEAQQRRLLGSYEQMMERLLEMQDGAYRQLRETLAVEEEVAQSLLELKECTRQGDTELQQLEVELQRTSKEDTCVQARLRQLITELQELREMEEELQRQERDVDEDNTVTIPSAVYVAHLYHQISKIQWDYECEPGMIKGIHHGPTVAQPIHLDSAQLSPKFISDYLWSLVDTTWEPEP
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc24.
What is the protein family that this protein belongs to?
Belongs to the SPC24 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.
Protein: MVD1_MOUSE
Sequence: MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL
What is the function of this protein?
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP).  Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
What are the official names of this protein?
Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISU2_ARATH
Sequence: MMMLRQTSRKAYLGLQASPLGLGRRLYHENVIDHFENPRNVGSFNRNDPNVGTGLVGAPACGDLMSLQIKVDDSGQIIDTRFKTFGCGSAIASSSVASEWIKGKTLDEVMTIKNAEIAKHLRLPPVKLHCSMLAEDAIKSAVRDYKEKQAKTNAAAAEETVKA
What is the function of this protein?
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (PubMed:17417719).  First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3).  In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins.  Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly protein 2, AtISU2, Protein ISCU-LIKE 2, NifU-like N-terminal domain-containing protein ISU2, NifU-like protein ISU2.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CASQ1_RABIT
Sequence: MNAADRMGARVALLLLLVLGSPQSGVHGEEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSIYVFKEDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKNKDSEHYKAFKEAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGYEFLEILKSVAQDNTDNPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDEDDDDDDDD
What is the function of this protein?
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.  Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits.  Can bind around 80 Ca(2+) ions.  Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.  Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity).
What are the official names of this protein?
Calsequestrin-1, Aspartactin, Calsequestrin, skeletal muscle isoform, Laminin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the calsequestrin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Sarcoplasmic reticulum lumen. Mitochondrion matrix. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells (PubMed:15731387). Preferentially forms linear and round aggregates in the endoplasmic reticulum (ER) of resting cells. In a minority of cells, homogeneously detected in the ER lumen. Colocalizes with STIM1 at endoplasmic reticulum in response to a depletion of intracellular calcium (By similarity).
Protein: CHED1_LEPIC
Sequence: MILEPDTVIDLFLQPGGFYWGKGNIRIRTLLGSCVSICFWHPSLLYGGMAHVMLPFRPSSIHSDDSLNAKYAEDAFQLFFEKLEGFKKQYQIKLFGGASMFSTEEEKLLELKSVRDIGMKNILSIKEHLIRNQLLISSEDLGGFSHRRIFFSLWDGEIYVERPEHT
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD 1.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: DEF_HAEI8
Sequence: MTALNVLIYPDDHLKVVCEPVTEVNDAIRKIVDDMFDTMYQEKGIGLAAPQVDILQRIITIDVEGDKQNQFVLINPEILASEGETGIEEGCLSIPGFRALVPRKEKVTVRALDRDGKEFTLDADGLLAICIQHEIDHLNGILFVDYLSPLKRQRIKEKLIKYKKQIAKS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: BORG2_HUMAN
Sequence: MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQHDVFGDISFLQGNYELLPGNQEKAHLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQALMLPLLSPVTFNSKQESFGPAKLPRLSCEPVMEEKAQEKSSLLENGTVHQGDTSWGSSGSASQSSQGRDSHSSSLSEQYPDWPAEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDLGPSLLDEVLNVMDKNK
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton.  May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes.  Induces pseudopodia formation in fibroblasts.
What are the official names of this protein?
Cdc42 effector protein 3, Binder of Rho GTPases 2, MSE55-related Cdc42-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BORG/CEP family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: KNL1_CAEEL
Sequence: MSMEPRKKRNSILKVRQAVETIEETVMNSGPSSTTTNRRVSFHNVKHVKQYDRDHGKILDATPVKEKITDTIGSDGILTPRGGNMDISESPACTSSFQVFGGGNLDKTMDMSLETTINENNETARLFETTRDPTLLYEKIVETTTKVTERIVSMPLDDTLAMFNTTNQEDKDMSVDRSVLFTIPKVPKHNATMNRTIPMDLDESKAAGGQCDETMNVFNFTNLEAAEMDTSKLDENNTMNAIRIPINSNVMPVDMDITEHHTLIEEKKNDTFGPSQLMDISAPQVQVNDTLAIFNSPRDICNKGLGVPQNLINIASNVVPVDMDITDQAVLNAEKKNDQFETSQLMDISIPKVLVNDTMAMFNSPKHVSKSSMDLEKTIEAADKSTKYPSIADEVEDLDMDMDITEQQPCEAGNQQNDGLQLQKEDLMDISVIRDSPAVNDTMAVFQSPARVKIGANNSIIDSQKSIVFGDEMSIDETQNDGTLTLPKSNVEVTTTNDVYTSLERQEENASENVSMINESSVHSEIDKKSFMLIEEERAFMHSSMIDVAQKLEDDGSSKTPVILASQSASLATKEPSALHNSSATLNNSMELDNNTLLKTMQITTCEDISMVHESIAVELNSNKEQEQFGDETLQKNDTSNTGANFTFQGHNETSQIMNNVDSEAVNTSKISTYSAFNLSINQSISKRRRSLLNSARESPRRVALENSIMSMNGQTMEALTEYRQNKTMQTSQDSMPSMSLNDSGRDILAMNTSVRSPHLNSSKTAAPGTPSLMSQNVQLPPPSPQFEMPDFDPAVVNVVYLTSEDPSTEQHPEALKFQRIVENEKMKVQHEIDSLNSTNQLSAEKIDMLKTKELLKFSHDEREAIMIARKDAEIKFLELRLKFALEKKIESDQEIAELEQGNSKMAEQLRGLDKMAVVQKELEKLRSLPPSREESGKIRKEWMEMKQWEFDQKMKALRNVRSNMIALRSEKNALEMKVAEEHEKFAQRNDLKKSRMLVFSKAVKKIVNF
What is the function of this protein?
Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division (PubMed:14522947, PubMed:15371340, PubMed:17129783, PubMed:18070910).  Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy (PubMed:15767665, PubMed:16273096).  Has a role in the correct localization of the spindly-like protein spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1 to kinetochores (PubMed:18765790, PubMed:18936247).  Required for the recruitment of spindle-assembly checkpoint components bub-1 and mdf-1/2 to unattached kinetochores (PubMed:19109417, PubMed:20729837, PubMed:24567362).
What are the official names of this protein?
Kinetochore null protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Chromosome, centromere, kinetochore. Note=Also found on the surface of chromosomes (PubMed:14522947). Subcellular localization dependent on expression of hcp-3, hcp-4, knl-3 and knl-2 (PubMed:14522947, PubMed:15371340, PubMed:16273096, PubMed:17339379). During anaphase of meiosis I, localized also to spindle-associated rod- shaped structures which depends on zwl-1 (PubMed:20729837).
Protein: RS19_AQUPY
Sequence: MGFKGAWNKRNRLIENPEEYYRLYKKLQRAYKLVREAIKRYGSFELLKGKTSLRDLEELLEERKQVLENLKKQLREAHKGKPKIEAEGDEQLKELIREVNRVQSEVRALEIITNRVRKYEEIYAQYKQMTEKKAYVDPKLWMRIRKMNEAGERKVVRTYSRATTIIPEFVGHTIAVHNGKTFIPVYITQDMVGHKLGEFAPTRTFKGHPDKTAKVVKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL34_ECOUT
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: HIS1_ALIF1
Sequence: MSSQRLRIAIQKKGRLSKECQELFKRCGMKFNISGERLVVHSENMPIDLLLVRDDDIPSLIMDGVVDLGVIGENELEEVRLERKALGEPSAFTTLRRLDFGGCRLSIAIDKDEVYNGPQDLAGKRIATTYPQLLKSFMDEQGIPFSTCILNGSVEVAPRAGLADAIADLVSTGATLEANGLKEAEVIFRSKATLIQREGEFDADKAALINKLLTRMQGCIQAKESKYIMLHAPTDKLDAIKDLLPGAEDPTVLPLSRDGAKVAVHLVSTENLFWETMEQLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_METS3
Sequence: MNLKVKTISNIGGEVKAPPSKSYSHRAVILASLADGTSKIHDMLFSQDVLSSINVCRALGANITKKDDYLEVIGTNGKLHNSSEVPIDLGNSGTTLRLMTSIASLADNEVILTGDDSLQTRPMEILTESLASLGVCAASINGNGKAPILIKPGYVGGETNILGNVSSQFISSILISAPLSENGVDLFVLPEFKSRPYVNMTCDIMAKFGVKIENEFFVRHDDCDRESKNCRIDEFKISKQEYKSCDYVVEGDYSSASYLLAAVAIYGGNAKILNLFKDSKQGDKLILNILKKMGAKIEIFDDYVEISSEGNLKGIDVDLSNAPDLLITVAILAALADGTTNITGVKHARVKETDRIATTCSELKKLGCKLKEFEDGMSIEGGIRSGVVDSHKDHRLAMAFSLVGLKHDIEIKNGEVFDVSFPNFIEAMSEIGVELELI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAA_STAAN
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFILGTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: Y1362_METJA
Sequence: MIDELISIIGIPALAFAISTYIPGIQRKIEARIQQRIGPSILAPGFWAFFKFLFKETKAPDANLPKLYNLLPLLSIVVLWALLSITSLTSFHILSNEIGIVGLLKLEEMMYVILGSLAFSIMGWKMPFIDECKGTPFIKTLKLSLEQLGAVRSFKMITIGSFPFYLATFLPFVQKKSIFLKDIVGEPFLFSLAGIFGAACYFIGYVIMIKEYPFSITHTKADVIEGPTMELIAKYRALYLASKELLLIALGSLFATLYLGIAPDIENPITIVENFAIALIFPILATFVRAFSPVLLFKQIYPISYVATLIGVIGFIFALLGW
What are the official names of this protein?
Uncharacterized protein MJ1362.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPQE_MYCLE
Sequence: MSRFKISLPALATRVAVLGFLTLMASVLGGCGAGQISQTATQEPAVNGNRVTLNNLALRDIRIQAAQTGDFLQSGRTVDLMLVAINNSPYVTDRLVSITSDIGTVALNGYTQLPTNGMLFIGTSEGQRIKPPPLQSNNIAKAIVTLAKPITNGLTYNFTFNFEKAGQANVAVPVSAGLAPRQT
What are the official names of this protein?
Putative lipoprotein LpqE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYI_MYCLE
Sequence: MTNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKTLDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLLVWTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPPFQYFYESARNAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMPYAQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDAMRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDRYILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEIIWRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDELNVKQIELTDAIDTYGRFEFTVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTAELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADWARVHRDFIAREILATSFEFGEPADSVAIGDGVRVSLLKV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_RICRO
Sequence: MNINKIALIYNHNSKHLAIIEEIKKLYNYCKIEEAEVIIVIGGDGELLHNIHRYMHLNIPFYGVNLGSLGFLMNPLDTKKLLQNIHDSTVSILNPLLMQVADTNGQIYTALAINEVSIFRKTNQAAKFRIEVNGIERMNELVADGALVATPAGSSAYNLSASGPILPLESNMLCLTPICSFRPRRWHGALLLSSATIKFEILNTNKRPVNATADFQEFNNITNVTVKSTKDKPVKLLFNKNHTLEDRIIKEQFGG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2149_ARCFU
Sequence: MIDRIKKIVFGGEREREVVELIGKQVELIIDTCELMKSIIERSDEAVVGDVCEAEKLGDAIRRDIVLKIHSGAFIPALRSDFCNLAEELDEILDELEDIAMLYLLIDFIPDELRDEFIRIADTNSKMAYLLLDAFNALEEGGLSDILLKIKILEEQIDSMKGRIYEKLKNIDFSGYAEWYYFIKFVEKLLNVSDLIEDAGDTIQVLSVSIR
What are the official names of this protein?
UPF0111 protein AF_2149.
What is the protein family that this protein belongs to?
Belongs to the UPF0111 family.
Protein: KDGT_ECOLI
Sequence: MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell (PubMed:15555, PubMed:6094479).  Expression of this specific KDG-uptake system may allow growth with KDG as the sole carbon source (PubMed:4359651).  Can also transport D-glucuronate (PubMed:15555, PubMed:6094479).
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease, 3-deoxy-2-oxo-D-gluconate-transport system.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR14_ADICA
Sequence: MAKKSLIEKENSKKKLVKKYNLLRQFLRREIKNSLRIQDKLIISEKLQSLPRNSARVRLRNRCSLTGRPRSNYRDFGFSRHVLREMAHTCVLPGVLKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.