PharMolix/UniProtQA huggingface dataset:
Protein: PNGK_PANCL
Sequence: LDVKKIICVACKIKPNPACKKICPK
What is the function of this protein?
Antimicrobial peptide active against Gram-positive bacteria M. luteus (MIC=1. 6 uM) and B. subtilis (MIC=3. 3 uM).  Less active against Gram-negative bacteria E. coli (MIC=63. 3 uM) and yeast C. albicans (MIC=24. 2 uM).  Not active against S. aureus and P. aeruginosa.  Has no hemolytic activity against human erythrocytes.  Probably acts by disrupting membranes of target cells.
What are the official names of this protein?
Panurgine K, PNG-K.
What are the subcellular locations of this protein?
Target cell membrane. Secreted.
Protein: TOP1_STRCO
Sequence: MSPTSETAKGGRRLVIVESPAKAKTIKGYLGPGYVVEASVGHIRDLPSGAAEVPEKYTGEVRRLGVDVEHDFQPIYVVNADKKSQVKKLKDLLKESDELFLATDEDREGEAIAWHLQEVLKPKIPVKRMVFHEITKDAIRAAVANPRELNQKLVDAQETRRILDRLYGYEVSPVLWKKVMPRLSAGRVQSVATRLVVERERERIAFRSAEYWDLTGTFATGRAGDASDPSSLVARLQTVDGRRVAQGRDFDSLGQLKSANTLHLDEANARALAAALENTRFAVRSVESKPYRRSPYAPFRTTTLQQEASRKLGFGAKSTMQVAQKLYENGYITYMRTDSTTLSDTAVSAARAQVTQLYGADYLPPQPRTYAGKVKNAQEAHEAIRPSGDRFRTPAETGLTGDQFKLYELIWKRTVASQMKDATGNSVTVKIGGAASDGRDVEFSASGKTITFHGFLKAYVEGADDPNAELDDRERRLPQVAEGDALTAEEITVDGHATKPPARYTEASLVKELEEREIGRPSTYASIIGTILDRGYVFKKGTALVPSFLSFAVVNLLEKHFGRLVDYDFTARMEDDLDRIARGEAQSVPWLRRFYFGEGDGTGGGGAADAGNGDGDHLGGLKELVTDLGAIDAREVSSFPVGNDIKLRVGRYGPYVERGEKDAENHQRADVPEDLAPDELSVELAEELLAKPSGDFELGTDPATGHAIVAKDGRYGPYVTEVLPEGTPKTGKNAVKPRTASLFKSMSLDTVTLDDALKLMSLPRVVGADAEGVEITAQNGRYGPYLKKGTDSRSLQTEDQLFEITLEEALAIYAQPKQRGRAAAKPPLKELGTDPVSEKPVVVKDGRFGPYVTDGETNATLRSDDSVEEITPERGYELLAEKRAKGPAKKTAKKAVKKTAAKKAPAKKAAATKKTAAAKTTAAKKTAAKSTAKKTTAKTAAKKATASKTSED
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: VF171_ASFWA
Sequence: MVVYDLLVSLSKESIDVLRFVEANLAAFNQQYIFFNIQRKNSITTPLLITPQQEKISQIVEFLMDEYNKNNRRPSGPPREQPMHPLLPYQQSPDEQPMMPYQQPPGNDDQPYEQIYHKKHASQQVNTELSDYYQHILALGDEDKGMDSTLKLPERTKRDSDDEDGMFSIKN
What are the official names of this protein?
Uncharacterized protein H171R, pH171R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H171R family.
What are the subcellular locations of this protein?
Virion.
Protein: TRPA_ECOBW
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NIKR_METBU
Sequence: MEQELMRIGVSLPDNLLNKFDSIIEGRGYSSRSEGIRDSIRTYINQYEWMSDIRGRRVGTITIIYDHTKRGLSNAVADIQHDYSDLIKSSVHIHLDHDNCLEVIIFDGEGELIKEMDERLMALKGVKYVKLNTAPPAEKI
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL29_BORA1
Sequence: MKASELRSKDAAELGKELESLLKAQFGLRMQKATQQLANTSQLRNVRRDIARVRTLLTQKAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ATPE_CHLAA
Sequence: MPIHLEIVTAERVILSDDVDMISAPTKDGRVGILPRHAPLMTILEPGELDIIKNGERTPFAVSGGFMEVLPHRVTILADTVERADEIDEARAEQARAEAEARRREAQSERDMALAEAKLRKEMVRLRVAQLHKIKRRQS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DISP3_MOUSE
Sequence: MDSEDDPLLQDVWLEEEQPEDEACRGIPGPGLQSGAQGCWRRWTLPSRPPTLGFWSTLGWAFTNPCCAGLVLFLGCSIPMVLSAFMFLYYPPLDIDISYNAFEIRNHEASQRFDALALALKSQFGSWGRNRRDLADFTSETLQRLISEQLQQLHLGNHSRPASRAPRSAPRDTVATQTSAANSSERRRREAPSPEGQVTNQSRARRGASRWDYSRTYVSANTQTHAHWRIELIFLARGDAERNIFTSERLVTIHEIERKIMDHPGFREFCWKPHEVLKDLPLGSYSYCSPPSSLMTYFFPTERGGKIYYDGMGQDLADIRGSLELAMTHPEFYWYVDEGLSVDNLKSSLLRSEILFGAPLPNYYSVDDRWEEQRAKFQSFVVTYVAMLAKQSTSKVQVLYGGTDLFDYEVRRTFNNDMLLAFISSSCIAALVYILTSCSVFLSFFGIASIGLSCLVALFLYHVVFGIQYLGILNGVAAFVIVGIGVDDVFVFINTYRQATHLEDPQLRMIHTIQTAGKATFFTSLTTAAAYAANVFSQIPAVHDFGLFMSLIVTCCWLAVLFTMPAALGLWSLYMAPLESSCQNSCHQKCGRKSSLHFPGDLFTAPERAGGGPAQGPLPYLDDDIPLLNVEDEPASLELGDVSLVSVHCEGLQPTPDANSRGQLLAQLQELLHHWVLWAAVKSRWVIVGLFASILILSLVFASRLRPASRAPLLFRPDTNIQVLLDLKYNLSAEGISCITCSGLFQEKPHSLQNNVRTSLEKKKRGSGVSWASRTETTAQESMSTVYISKVKSKGHPAVYRLSLNASLPAPWQAVSPGDGEVPSFQVYRAPFGDFTKKLTACMSTVGLLQAASPSRKWMVTALACDARRGWKFDFSFYVATKEQQHTRKLYFAQSHKPPFHGRLCVAPPGCLLSSSPDGPTKGFFYVPSDKVPKARISATFGFNPCVNTGCGKPAVRPLVDTGAMVFVVFGIIGLNRTQQMDNHVIGDPGSVIYDSSFDLFKEIGHLCRLCKAIAGNSELVKPGGAQCLPSGYSISSFLQMLHPECKELPEPNLLPGQLSHGAVGVKEGRVQWISMAFESTTYKGKSSFQTYSDYLRWESFLRQQLQTFPEGSALHRGFQTCEHWKQIFMEIIGVQSALYGLVLSLLICVAAVAVFTTHVLLLLPVLLSILGIVCLVVTIMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGYLLAGENLPPQLSQDPSSQRQWRTLEAVRHVGVAIVSSALTTVIATVPLFFCIIAPFAKFGKIVALNTGVSILYTLTVSTALLGIMAPGSFTRTRTSFLKALGAVLLAGALGLGACLVLLRSGYKIPLPSGATL
What is the function of this protein?
Plays a role in neuronal proliferation and differentiation.  Plays a role in the accumulation of cellular cholesterol.  Involved in intracellular lipid droplet formation.  May contribute to cholesterol homeostasis in neuronal cells.
What are the official names of this protein?
Protein dispatched homolog 3, Patched domain-containing protein 2, RND-type protein RNDEu-2.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Predominantly localized to cholesterol-enriched domains within the membrane (By similarity). Localizes to cytoplasmic punctate vesicular structures (By similarity).
Protein: KCC1B_EMEND
Sequence: MASQVQPGQKPKVQPCRYKTGKTLGAGLYSVVKECVHIDTGQYYAAKVINKRLMVGREHMVRNEIAILKQVSTGHQNILTLVDYFETMNNLYLVTDLALGGELFDRICRKGSYYESDAADLVRAILSAVAYLHDHGIVHRDLKPENLLFRTPEDNADLLIADFGLSRIMDEEQLHVLTTTCGTPGYMAPEIFDKSGHGKPVDIWAIGLITYFMLCGYTPFDRETNLEEVQAIATANFSFTPVEYWRGVSQEARDFIKRCLTVNPKKRMTAHQALQHPWINPPYDTTDDLGSGEDLLPNIKKNFNARRTLHKAIDTVRAINKLRENGGLMMDGIMSVDPKPEHVNGSEVVEDRTTPRERENEDAMEIDSRSNARGQTEQQIREQERKVKETVAGLWSRTAPRSER
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade.  Required in G1-phase of the cell cycle for proper timing of the initial nuclear division after germination, but not for subsequent mitoses.  Required for the normal temporal regulation of nimX activity.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase cmkB, CaMK B, CaMKI/IV homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: ISPE_CHLT2
Sequence: MHFLSPAKLNLFLQILGRREDDFHEIVTRYQAIAFGDQLSLSISSRDSLQVINACHLETPSNSIWKSVALFRRYTGITTPVSWRVVKQIPVGAGLAGGSSNAATALFALNQIFKTGLSDEEMRSLAEQIGMDTPFFFSTGAALGVARGEKIIALEESVSDRYVLYFSSEGVLTSRAFAVVQPSDCSSRKNLEYTQNDLEKPVFRLRLDLKEKKHWLESLWAELPVHIGLTGSGATLFVRYPEILEEDPSYAAQIQRAVTLSGGLLTSPIRRDPTAWYSIYSESALAAT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ODO1_STAHJ
Sequence: MAKDNKDVTEAPVNFGANLGLMLDLYDDYLQDPSSVPDDLQVLFSTIKNGEAHVAAKSTTEGSGSSAGDGTIKRIMRLIDNIRQYGHLKADIYPVNAPKRTNLPKLEIEEFNLDKETLENVSAEIVSDHFKDIYDNAYEAIERMEKRYKGPIAFEYNHINNNKERTWLKRRIETPYRANINNDERKKLFDTLAHVEGFEKYLHKNFVGAKRFSIEGVDTLVPMLQHTLKRAAEIEINNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLELTAGWTGDVKYHLGGVKTTSSYGIEQRISLANNPSHLEIVAPVVIGKTRASQDDTKHAGKPTTDFHKGMPIIIHGDAAYPGQGINFETMNLSNLDGYSTGGALHIITNNRIGFTTEPVDGRSTTYSTDIAKGYDVPILHVNADDVEATIEAIDIAMEFRKEFHKDFVIDLVGYRRYGHNEMDEPSITNPLPYHNIRKHDSVEIIYGNKLVEDGVISKEQMEDVMDKVQKEMRAAQDKIDKSDKMDNPDMERPESLQEPLQSDDKDFSVDHLKEINDAMLTYPEDFHVLKKLNKVLEKRREPFESENGLVDWAQAEQLAFATIVQDGISVRLTGQDSERGTFSHRHAVLHDEENGDTFTPLHHVPNQKATFEVHNSPLSEAAVVGFEYGYNVENKNSMNIWEAQYGDFSNMAQMMFDNFMSSARAKWGERSGLTLFLPHAFEGQGPEHSSARLERFLQLAAENNSTVVNLSSSSNYFHLLRAQAKSLGTEAMRPLIVMSPKSLLRNKTVAKPIDQFTSGGFKPIIVEDGNKEKVTKLVLASGKMFIDLKEHLAKNPDDSILLVAVDRLYPFPEGEIKEVLNELPNLETVSWVQEEPKNQGAWLFVYPYLKSLVGNQFNLSYHGRIQRAAPAEGDGEIHKLVQNQIIESSIEK
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RS18_BURCH
Sequence: MARPTGKKFDKRRQQQNPLFKRKKFCRFTAAGVEQIDYKDTETLKDFIGENGKITPARLTGTKAHYQRQLDTAIKRARFLALLPYTDQHKA
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SECB_SHESW
Sequence: MAEVANNEQQAPQFNIQRVYTKDVSFETPNSPAVFQKEWNPEVKLDLDTRSAKLADDVYEVVLSLTVTAQNGGETAFLCEVQQAGIFSISGLTEPQLAHSLGAYCPNILFPYAREAVGSLVGRGTFPQLNLAPVNFDALFAQYVQQRQAAATAPAAEEANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2_CANAW
Sequence: MTSSINILLLLHPTVVTDAQLVEQIKSKIYQSHNNNNNNNGGTTTTTTGTVNINLNQQIIDRVTKGIIELPYDYYDEIIYINPNNESQYREIPISLMQLIYKLLKSNGKFKGDLPLDQNLDVLMTGFIIEEEEKEKEENNLEGELVNVWVKPIPVDEPVVTLLKKKTTTSNTTTKKKSLPLFKKLNKDEINNSDKDINNDNITNNNNNNNNNKRKLVETKLTYFSSDDENSSDGSVSENDDIDDDDELIDENDLLNFNNNNNNNTNGGSLLSDKLITPRKCDISLNGGKKRKKACKDCTCGLKELEELEVSNQQNLQDQILGKLAQSATLEAIKIEERLKQQQQQQQQQKVKVKFTEEDLSEIDFTVQGKTGGCGSCALGDAFRCDGCPYLGLPPFKPGEVVKLDGFGEDI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: APT_KOSOT
Sequence: MNLKDFIRDIPDFPKPGIIFKDVTPMLKDPGAFKVCISSLKELVKDFEFNLIVAPEARGFIFAAPLALELEKGFVPIRKPGKLPYKTVSVEYSLEYGTATLEMHTDAIKEGDKVLIVDDVLATGGTMKAIAEMVEKVGGTISGIVSLVELSFLEPRKKLSGYEVRSIITY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CODY_STRU0
Sequence: MPNLLEKTRKITSILQRSVDSLDAELPYNAMASRLADIIDCNACIINGGGTLLGYAMKYKTNNDRVEEFFEAKQFPDSYVKAASRVYDTEANLPVENELTIFPIESKNTYPDGLTTIAPIYGGGMRLGSLIIWRNDKKFLDEDLILVEISSTVVGIQLLNLQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSA1_AGRFC
Sequence: MRAETQTIKMTEASSPTPVLEMRGISQIFPGVKALDGVDIALYPGKVTALIGENGAGKSTLVKILTGIYRPNEGEILLDGKAVHFHSAQDAIDAGVTAIHQETVLFDELSVGENIFLGHAPKGRFGLIDWKTINERARILLEQLESTIDPTIRLKDLSIAQRHLVAIARALSVEARIVIMDEPTAALSRKEIDDLFRIVENLKRQGKAILFISHKFDEVYEIAENYAVFRDGKMVGAGTLATTPQDEIVRLMVGRDVTNAFPKQAVTLGPTVLSVRDYSHQTEFRDISLDLRKGEILGLYGLIGAGRSELCQSLFGITRPASGEVTLDGQPLTIRSPEDAIRAGIVYVPEERGRHGLALDMPIYQNMSLPSLTRTSRKGFLTAANEFALARKYAARLDLRAAALSVPVGTLSGGNQQKVVIGKWLATKPKVIILDEPTKGIDIGSKAAVHGFISELAAEGLSIIMISSELPEILGMSDRAIVMREGLMAGQFERAEFSPEKLVRAATGNA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL28_THISH
Sequence: MARVCQITGKRPVTGNNVSHAHNKTRRRFLPNLHSHRFWVESENRWVRLRISSKGLRIIDKKGIDAVLADLRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GLNE_SALPB
Sequence: MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALDSVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRFFRRRIMVRIAWAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQTQTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERSEPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQLMPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMIASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDPQLTSQFDTVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQALTVAYTTLRDELHHLALQELPGHVAQTCFSKERALVQASWRKWLVAV
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: SYA_STUS1
Sequence: MKSAEIREAFLRFFEEKGHTRVASSSLIPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWEFLTSDKWLKLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNKGAPYASDNFWAMGDTGPCGPCTEIFFDHGEHIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERISAVLQHVNSNYEIDLFQSLLNAAADAIGCANEGQASLKVVADHIRSCGFLIADGVTPSNEGRGYVLRRIIRRACRHGNKLGAKGSFFHRIVAALVAEMGDAFPELKQQQAHIERVLKNEEEQFAKTLEQGLKILEQDLAGLAGSVIPGEVVFKLYDTYGFPVDLTGDIARERNLTLDEEGFEREMQAQRERARSASAFGMDYNSLVKVEGETRFIGYQGTSGSGKVLALFKQGMLVDSLSAGEEGVVVLDQTPFYAESGGQIGDCGYLEAQGLRFDVRDTSKAGGAFLHHGIVDSGTLTTGAQVEATVDASVRQATALNHSATHLLHAALREILGEHVSQKGSLVDSQRLRFDFSHFEAIKPEQLRALEDRVNAEIRRNSAVEIEETDIDTAKAKGAMALFGEKYGDTVRVLTMGGGFSVELCGGTHVNRTGDIGLFKITSEGGVAAGVRRIEAVTGAPALAYLNDAEEQLKQAASLVKGSRENLLDKLGGLLERNRQLEKELEQLKAKAASAAGNDLAASAVEVNGIRVLAARQDGLDGKALLALVDQLKNKLGSAVILLGGVQDDKVVLVAGVTQDLTSRLKAGDLMRQAAAAVGGKGGGRPDMAQGGGTDAAKLDEALALALPFAQQAL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: SYS_STRZT
Sequence: MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVKVETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTTTLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTGARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTYDLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEALRPYMGGAEVIKP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAES_STAAS
Sequence: MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLTTIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSFNKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIKESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHENRTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIAISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDIDVGTTMTVTLHKLDITS
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion.  Probably functions as a membrane-associated protein kinase that upon sensing the appropriate signal, autophosphorylates and in turn activates the cytosolic response regulator SaeR (By similarity).
What are the official names of this protein?
Histidine protein kinase SaeS, Sensor protein SaeS, Staphylococcus exoprotein expression protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNCB_BURA4
Sequence: MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFTDIELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEMWAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQLYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPVDDDASQ
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: KBX32_HOFGE
Sequence: MKLTILILLVITSFCSCGILREKYAHKAIDVLTPMIGVPVVSKIVNNAAKQLVHKIAKNQQLCMFNKDVAGWCEKSCQQSAHQKGYCHGTKCKCGIPLNYK
What is the function of this protein?
Has antimicrobial activity against yeasts and bacteria.
What are the official names of this protein?
Hg-scorpine-like 2, HgeScplp2, Hgscplike2.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL24_SYNY3
Sequence: MTKTKPAPHRVKMHVKKGDTIQVISGKDKGKVGEVLRTIPSHSQVVVKGVNIRTKHVKPRQEGESGQISSYEAPIHSSKVMLYSTKEKIASRICYTVTDDGRKVRMLKKTGEIID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: BGAL7_ARATH
Sequence: MKMKHFTRLLSLFFILITSLSLAKSTIVSHDERAITINGKRRILLSGSIHYPRSTADMWPDLINKAKDGGLDAIETYVFWNAHEPKRREYDFSGNLDVVRFIKTIQDAGLYSVLRIGPYVCAEWNYGGFPVWLHNMPNMKFRTVNPSFMNEMQNFTTKIVKMMKEEKLFASQGGPIILAQIENEYGNVISSYGAEGKAYIDWCANMANSLDIGVPWLMCQQPNAPQPMLETCNGFYCDQYEPTNPSTPKMWTENWTGWFKNWGGKHPYRTAEDLAFSVARFFQTGGTFQNYYMYHGGTNFGRVAGGPYITTSYDYHAPLDEFGNLNQPKWGHLKQLHTVLKSMEKSLTYGNISRIDLGNSIKATIYTTKEGSSCFIGNVNATADALVNFKGKDYHVPAWSVSVLPDCDKEAYNTAKVNTQTSIMTEDSSKPERLEWTWRPESAQKMILKGSGDLIAKGLVDQKDVTNDASDYLWYMTRLHLDKKDPLWSRNMTLRVHSNAHVLHAYVNGKYVGNQFVKDGKFDYRFERKVNHLVHGTNHISLLSVSVGLQNYGPFFESGPTGINGPVSLVGYKGEETIEKDLSQHQWDYKIGLNGYNDKLFSIKSVGHQKWANEKLPTGRMLTWYKAKFKAPLGKEPVIVDLNGLGKGEAWINGQSIGRYWPSFNSSDDGCKDECDYRGAYGSDKCAFMCGKPTQRWYHVPRSFLNASGHNTITLFEEMGGNPSMVNFKTVVVGTVCARAHEHNKVELSCHNRPISAVKFASFGNPLGHCGSFAVGTCQGDKDAAKTVAKECVGKLNCTVNVSSDTFGSTLDCGDSPKKLAVELEC
What are the official names of this protein?
Beta-galactosidase 7, Lactase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.