PharMolix/UniProtQA huggingface dataset:
Protein: AROC_STRP7
Sequence: MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RK36_CHLRE
Sequence: MKVRASVKKMCDNCRVIKRKGKVMVICSNAKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YHEU_ECO24
Sequence: MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: SECA_GEODF
Sequence: MFSALIKKIVGSKNERELKRLWPIVEQINNLEAGISKLSDDQLRNKTSEFKERYGRGETLDSLLPEAFAVCREAGKRVLGMRHFDVQLIGGMVLHQGKIAEMKTGEGKTLVATLPSYLNAITGKGVHVVTVNDYLARRDSEWMGRIHNFLGLRVGVIIHGLDDEERRDAYNADITYGTNNEFGFDYLRDNMKFALEDYVQRDFNFAIVDEVDSILIDEARTPLIISGPTEDSTDKYYIIDRIIPLLKKGEVVEEEANTLSGKRKRYTGDYTVDEKAKSATLTEEGVLKVEKLLKIENLYDPRDIETLHHVNQALRAHALFKLDVDYVVKEGEVIIVDEFTGRLMPGRRWSDGLHQAIEAKEGVKIENENQTLATITFQNYFRMYEKLSGMTGTADTEAEEFHKIYKLDVTVIPTNRVLLRPDFPDVIYKTEREKFNAVIEEVKELHAKGQPVLVGTISIEKSEELAELLRRQGIPHNVLNAKQHEKEAEIVAQAGRKGMVTIATNMAGRGTDILLGGNAEAMSKQWRRSNPEVSEEEFTKVSAQFKEQCVKEHDEVVSLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLQDDLLRIFGSERVSKIMDMLKIEEGEAITHGLITKAIENAQRKVEAHNFEIRKHLIDYDDVMNKQREVIYAQRREILAGETIRESFVEMVNDAVADLAEGYAIEKVSATEWDWQGLSESVFKLFGFHVDIPPQTMERLNPGNLRDLLQEKVQEVFSEKVTEFGDELIDHLIKVIMLQSIDAQWKDHLLSIDHLKEGIGLRGYGQKDPKQEYKKEAYQLFMDMMGRIREEVVEKIFWVQIAREEDVERMEEQQKRQRLVFNAGDEPQAQQPATSKKVGRNEPCPCGSGKKYKQCCGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RSMH_ECOUT
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_PARDP
Sequence: MSRIDDTFARLSETGGKAFVAYMMGCDPDFDTSLQIMRGLPGAGVDIIELGMPFTDPMADGATIQAAGQRALAAGGSVSRVLDMVRAFRRDDDATPIVLMGYYNPIYARQGGVDRFITEAVEAGVDGLIVVDLPPEEDAELCLPAREAGLNFIRLATPTTDDRRLPAVVRNTSGFVYYVSVTGITGGPAANAAEVAPEVARIRAAAKLPVVVGFGISTPEAAQAVAGVADGCVVGSAIVKLIGEGRPVPEILSFVADLAQGAHSA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CVPA_HAEIN
Sequence: MIDYIIIGIIAFSILVSLLRGFVREVLSLGSWIVAFIVASQFYPYLAAYLTQIESMYIRNGTAIAILFVLTLIVGAIVNYVISQLVDKTGLSGTDRVLGAAFGLVRGALIVAALLFFMDTFTNFEQTDWWKESQLIPHFGFIIEWFFQQLQASSSFLTPTLNQ
What are the official names of this protein?
Colicin V production protein homolog.
What is the protein family that this protein belongs to?
To E.coli CvpA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCHJ_ECO24
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELIAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: Y059B_AFV1Y
Sequence: MRKVAFKVNEDLLELLDKYAIKHGLSRSEVIREAIKNMVKEELEKDSIIVARVEKIRIW
What are the official names of this protein?
Uncharacterized protein ORF59b.
Protein: CISY_CAEEL
Sequence: MSLSGMAIRRLITKGVIPVCQVAPLSTSAEGSTNLKEVLSKKIPAHNAKVKSFRTEHGSTVVQNVNIDMIYGGMRSMKGMVTETSVLDPEEGIRFRGYSIPECQKLLPKAKGGEEPLPEAIWWLLCTGDVPSEAQTAAITKEWNARADLPTHVVRMLDNFPDNLHPMAQFIAAIAALNNESKFAGAYARGVAKASYWEYAYEDSMDLLAKLPTVAAIIYRNLYRDGSAVSVIDPKKDWSANFSSMLGYDDPLFAELMRLYLVIHSDHEGGNVSAHTSHLVGSALSDPYLSFSAAMAGLAGPLHGLANQEVLVFLNKIVGEIGFNYTEEQLKEWVWKHLKSGQVVPGYGHAVLRKTDPRYECQREFALKHLPNDDLFKLVSTLYKITPGILLEQGKAKNPWPNVDSHSGVLLQYFGMTEMSFYTVLFGVSRALGCLSQLIWARGMGLPLERPKSHSTDGLIKLALAAKK
What are the official names of this protein?
Probable citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: H2B3A_MOUSE
Sequence: MPEPSRSTPAPKKGSKKAITKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
H2B.U histone 2, Histone H2B type 3-A.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYP_THEAC
Sequence: MENKKENFSEWYNEIITLAELSDKRYPVKGMNVWLPYGWKIMSLIDSIVRRAVDKRNFQEVNFPILIGRSMLEVEFEHIRGFENEIYWVTKGGKEKLEEELALRPTSESAMYPMFSLWIRSHADLPLKIYQIVSVYRYETKHTRSFIRIREIHFFEAHTAHATYEDAEAQMDQYKEIWREISSLLCLPYFYDQRPDWDKFPGAMYTIAFDTVLPSGRSLQIGTIHQYGTNFSKNYDIKYLKEDGTFDYAHQTTYGMSERLLAAIIGIHGDDKGLVLPPDVAPIQVIIIPIPGAGVMEYARDVENTLNSINIRVKVDDRENYTPGYKFNDWEMRGVPLRIEIGEREVKNRTLTISMRNIQGKLTIERSKLIYEVPDTLIRIREKMMENAQKVFKDHVFRATKLEEFNRDGLITAFWCGSKECSDKIEAETEKSVLGFMVDSSETGKCVVCGKNGKMAVFSRSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAX2_BOVIN
Sequence: MFLSPGEGPAAEGGGPGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEVPALPFARPPTMPLSLEPWLGPGPPAVPALPRLLGSGPGLQGSFGPHAFSPAFMDGFTLEEGSLRLLAKEHVQALDRAWPSA
What is the function of this protein?
May be involved in modulating the expression of photoreceptor specific genes.  Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter (By similarity).
What are the official names of this protein?
Retina and anterior neural fold homeobox protein 2, Q50-type retinal homeobox protein, Retina and anterior neural fold homeobox-like protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Z354C_MOUSE
Sequence: MAVDLLAARGTEPVTFRDVAVSFSQDEWLHLDPAQRSLYREVMLENYSNLASLGFQASIPPVIGKLQKGQDPCMEREAPEDTCLDFEIWPEIEALPPKQDVLTKETSHGLIKNGSTKCVYWKISFGELVKTECRDIAQEQEKKVHGPGAESPKETTSEDGTPTGFEPEKPLFISKALVSQEGDPTESVPATYHTSEKDLPQDFDLMRSFQMYPGQKPHVCSECGKGFTQSLHLLEHKRLHTGEKPYKCSECGKSFSHRSSLLAHQRTHTGEKPYKCSECEKAFGSSSTLIKHLRVHTGEKPYRCRQCGKAFSQCSTLTVHQRIHTGEKLYKCAECDKAFNCRAKLHRHQRIHTGEKPYKCAECGKGYSQFPSLAEHQRLHTGEQLCQCLQCGRTFTRVSTLIEHQRIHTGQKPYQCNECGKTFNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQYSFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHLKERLYKWKEYGTPFIYGSSLTPYQKFLKGDKPENFNSSL
What is the function of this protein?
May function as a transcription repressor.  Binds to 5'-CCACA-3' core sequence.  Suppresses osteogenic effects of RUNX2.  May be involved in osteoblastic differentiation (By similarity).  Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (PubMed:27446912).
What are the official names of this protein?
Zinc finger protein 354C, Kidney, ischemia, and developmentally-regulated protein 3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLIA1_CRODU
Sequence: MRLILLSGLLLLGTFLVNGHDADPEGEVLNSVLLTLMKLQKEFTNLFHAFLTVHKARSFGSGSERLYVSNKEIKNFEALKVICKQAGGQIPSPQLENQNKAFANVLERHNKEAFLVVGDSGNFTNWAAGQPNKADGTCVKADKQGFCHSTSCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor B1, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: QUEA_BRUAB
Sequence: MRVDLFDFDLPEERIALRPVEPRDHAKLLHVRPGEPFEDRHVYDLPDLLQPGDALVFNDTKVIPAQLEGMRERTGNISQVSATLHMRVGPDRWKAFLRPAKRVKEGDRIRFGHSGTSCFLGTLDATVAEKGDSGEALLVFDLSGAVLDEAIAAVGHIPLPPYIASKRPEDERDRKDYQTVYAREEGAVAAPTAGLHFTPDLLEKIKARGIEEHFVTLHVGAGTFLPVKADDTGDHKMHAEIGHVSQRTASALNAVHERGGRIICVGTTSLRLIESATGEDGVVRPWSGATDIFITPGYRFRAVDLLMTNFHLPRSTLFMLVSAFSGLDTMHAAYNYAIADGYRFYSYGDASLLERIDHDRHSA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SULDN
Sequence: MRHRHGYRKLGRTSSHRAALLKNLSISLIEHGKIETTVEKAKELRSYVEKLITVAGKNDSNAHKAVFAALQSKEATKKLVNEIAPKYVERAGGYTRIIRTRIRRGDATTMAFIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UBIB_ECOLI
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZIP2_YEAST
Sequence: MIIERWEVKLSKCNQNVGGYSVLSGNLKENIKLGRRAQKYLKELRNLQLKPLKIGGYENCGTINGEEYFLEVIHITSGRQKIDVAVGKTWNVTNIENDNKEELQYELFKEKLKVGKQDMLFFSWMKSLSVQLNAPLHQKMTEHGLADDNTRLEWFNIPLLRRSQYRKKVPYPSLRQMSSVLEVQCSTLTEEKLNFCVGFSDKPLSEWKPQIFEQTYNRYRLQRISPEKSFKYKSRCSKYNFKTSSQSWVVKVPEHDQQLNTFEKRYDELFDAQFNKLEFFKIRMKKLKKNKPIEKKNYKIWCLEKEDLKDLVWDPLKRICNHSRYAIFEHVTINREAYSIKPLRLTFQKLDSGSLDLIDNQKKTFGSIKLAMSMPDVKKTENQSIEESERHDETAIETQEFDENDCLSSKADINTSLAPQKRSFIDNELMSMLVTKKKIKKDKDVSDTGISSTSYLINSGTYANSHIEIPTSNSVYNGKEDCSFNNYSVKHSILEEDIENKCIAVNENKVIENQKVIQSLCKNSHLDLIEQSYFGECDFIINHSTCVYKIQASRFMQLRNNGSLHYDKAVNDLLTEFQRVIIIVEFSEIIQDVDPDLFWKIKLYLLNSRVDVFFIHETTDFFIDWMKYFIARWAFSYNDEKEKNIANADILLDLGFNILLVRKIFQTYSLEEFFMAIIKEESKAVKMLTVSQMTRLKKLLTLEW
What is the function of this protein?
Required for initiation of meiotic chromosome synapsis.  Involved in synaptonemal complex formation, a structure that tethers a pair of homologous chromosomes along their lengths and plays a central role in recombination and homolog segregation during meiosis.  Required for the normal localization of MSH4 to chromosomes.
What are the official names of this protein?
Protein ZIP2, Zipping up meiotic chromosomes protein 2.
What is the protein family that this protein belongs to?
Belongs to the ZIP2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=localizes to a meiosis specific chromosomal structure called the synaptonemal complex (SC) formed during meiotic prophase.
Protein: CHT_EMENI
Sequence: MSPVLKKYKAAAVNAEPGWFDLEESVRRTIHWINEAGRNRCKLIAFPELWIPGYPYWMWKVNYQESLPLLKKYRENSLLSDSEEMRRIREAARANKIYVSLGYSEVDLASLYTTQVLISPAGNILNHRRKIRATHVERLVFGDGTGDTTESVVQTEIGRVGHLNCWENMNPFMKSYAASLGEQVHVAAWPLYPGKETLKYPDPYTNVAEANCDALANELPQLVTPAYAIETGTYTLAPWQTITEEGIKLNTPPGKPLEDPNIYNGHGRIFAPDGRNLVPHPAKDFQGLLYVDIDLDEIHLTKSLADFGGHYMRPDLIRLLVDGNRKDLVVSEDRINGGIKYTSTMDRVGLTKPLEAPKPTDQKE
What is the function of this protein?
Catalyzes the hydration of cyanide to formamide.  Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
What are the official names of this protein?
Cyanide hydratase, CHT, Cyanide-degrading nitrilase, Formamide hydrolyase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: ARNB_ECO5E
Sequence: MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNHALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLQGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADINAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENIARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPSLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: PEPQ_SALNS
Sequence: MESLAALYKNHIVTLQERTRDVLARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEEVEVVALPKADGIGSQLPAARGNIGYIGPVPERALQLDIAASNINPKGVIDYLHYYRAYKTDYELACMREAQKMAVSGHRAAEEAFRSGMSEFDINLAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPSEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAHLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPSKYPYLRCTRVLQPRMVLTIEPGIYFIESLLAPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHENGVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: PPIE_BOVIN
Sequence: MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAIDNMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGSEPPKVETQEGEPAVKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEITDGLDVLRQIEAQGSKDGKPKQKVIISDCGEYV
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Combines RNA-binding and PPIase activities.  Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules.  Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.  Inhibits KMT2A activity; this requires proline isomerase activity.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophilin E, Rotamase E.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: P43_XENLA
Sequence: MKNVGETGPGKCQLLRCPAAGCKAFYRKEGKLQDHMAGHSEQKPWKCGIKDCDKVFARKRQILKHVKRHLALKKLSCPTAGCKMTFSTKKSLSRHKLYKHGEAVPLKCFVPGCKRSFRKKRALRRHLSVHSNEPLSVCDVPGCSWKSSSVAKLVAHQKRHRGYRCSYEGCQTVSPTWTALQTHVKKHPLELQCAACKKPFKKASALRRHKATHAKKPLQLPCPRQDCDKTFSSVFNLTHHVRKLHLCLQTHRCPHSGCTRSFAMRESLLRHLVVHDPERKKLKLKFVRGPSKFLGRGTRCRTPVVEEDLSHLFSRKLLFHFKTRLETNLSGLFNERQLREPAEPEVNLSGLFQRPQGRAKAEKSA
What is the function of this protein?
p43 is a 5S RNA binding protein which is a major constituent of oocytes and comprises part of a 42S ribonucleoprotein storage particle.
What are the official names of this protein?
P43 5S RNA-binding protein, 42S P43, Thesaurin-B.
Protein: CC85B_MOUSE
Sequence: MEAEAGGLEELTDEEMAALGKEELVRRLRREEAARLAALVQRGRLMQEVNRQLQGHLGEIRELKQLNRRLQAENRELRDLCCFLDSERQRGRRAARQWQLFGTQASRAVREDLGGCWQKLAELEGRQEELLRENLALKELCLALGEEWGPRGGPGGAVGSGAGPTPELALPPCGPRDLGDGSSSTGSVGSPDQLPLACSPDD
What is the function of this protein?
Functions as a transcriptional repressor.  May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth.  May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (PubMed:15644333, PubMed:22666460).  Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 85B, Hepatitis delta antigen-interacting protein A homolog, Delta-interacting protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC85 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, adherens junction.
Protein: I1BH_CONRA
Sequence: GPSFCKANGKPCSYHADCCNCCLSGICAPSTNWILPGCSTSSFFKI
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.17.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CGT_MOUSE
Sequence: MKSYTPYFMLLWSAVGIARAAKIIIVPPIMFESHLYIFKTLASALHERGHHTVLLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAVELVDILDHYTKNCDMMVGNQALIQGLKKEKFDLLLVDPNDMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLTDRMNFLERMKNTGVYLISRIGVSFLVLPKYERIMQKYNLLPAKSMYDLVHGSSLWMLCTDVALEFPRPTLPNVVYVGGILTKPASPLPEDLQRWVSGAQEHGFVLVSFGAGVKYLSEDIANKLAGALGRLPQKVIWRFSGTKPKNLGNNTKLIEWLPQNDLLGHSNIRAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWNTVTEGELYDALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTTYWIDYILRHDGARHLRSAVHQISFCQYFLLDIAFVLLLGAVLLYFILSYVTKFIYRKIKSLWSKNEHSTVNGHYQNGIRNGKYKGNGRVKHEKKVR
What is the function of this protein?
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.  Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides.
What are the official names of this protein?
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Endoplasmic reticulum.
Protein: ASSY_ECOSM
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_HAEIG
Sequence: MAAKIISGTELSKQIKANLADKITHYIEQGKRVPGLAVILVGADPASQIYVGNKRKSCEEVGILSKSYDLPETTTQNELLAIIDQLNADKNIDGILVQLPLPKQINAEAIIEHIDPKKDVDGFHPYNVGRLCQRIPTLRACTPYGVMKLLETTGIDLHGKHAVIVGASNIVGRPMSLELLLAGATVTVTHRFTKNLENHVRQADILVVAVGKPNLISGDWIKESAVVIDVGINRVDGKLVGDIEFDKAAEKAAYITPVPGGVGPMTVAMLMSNTLYAYEHNK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.