PharMolix/UniProtQA huggingface dataset:
Protein: PDRP_GEOMG
Sequence: MNGSMRHIYLFSDATGETVERVLRAALSQFRDVEARIHRMSKIRTREDILSALEDVLKEPGIVIYTLVDAELAQLLRDEAEAHGLDALDLISSLLFKLSDFFGVAPQNEPGLLYELNTEYHKRIEAVDFTVKHDDGQDPRGLSKADFVLVGVSRSSKTPLSMYLAHKGYKVANVPLVKGIDPPAELFKVDQNKIVGLLIDPHRLLEIRSVRLKNLGQMSRGSYADYEKIEDELNYCRQLYRRNPQWLVIDVTKRSVEESAAEIIQKLCS
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: EFG_PORG3
Sequence: MAIDKELQFTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWNYNNQKYKINLIDTPGHVDFTVEVERSLRILDGAVAAFCAVGGVEPQSETVWRQAEKYNVPRIGYVNKMDRSGANFFEVVRQLREVLGANPCPIQIPIGAEETFKGVVDLVSMKALVWNDETMGAKYDVEDIPAELVGEAEEWRDKMLETLADCDDTLMEKYFDDPSTITEDEIIAALRKGTLAMQINPMLCGSSFKNKGVQTLLDAVCKFLPSPADTPTVEGTDPSDPNKVIERKTSPNEPLCALAFKIATDPYVGRLCFFRVYSGELPAGSYVYNARSEKKERISRLFQMHSNKQNPKEVIGCGDIGAGVGFKDIRTGDTLCDENHPIVLESMDFPDPVIGIAVEPKTQKDLDRLGVGLAKLAEEDPTFRVQTNEDSGQTVISGMGELHLDIIIDRLRREFKVECNQGRPQVSYKEAINDPVELREVYKKQTGGRGKFADIICRVEPADADFEGELQFVDEVKGGNIPKEFIPSIQKGFQRAMKNGVLAGYPLDQLKVTVIDGSFHPVDSDQLSFEICALQAFKNACEKAHPTLMEPIMKLEVVTPEESMGDVIGDLNKRRGQVEGMESSRTGARIVKAKVPLAEMFGYVTALRTITSGRATSTMTFSHYSEVPSTIAKQVLTEAQGRVDLIK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKAI1_HUMAN
Sequence: MVFAPGEKPGNEPEEVKLQNASKQIVQNAILQAVQQVSQESQRREERISDNRDHIQLGVGELTKKHEKK
What is the function of this protein?
Protein kinase A (PKA)-binding protein.  Binds to type II regulatory subunits of protein kinase A (PKA) and may block the A-kinase anchoring protein (AKAP)-mediated subcellular localization of PKA (PubMed:25653177).
What are the official names of this protein?
A-kinase anchor protein inhibitor 1.
Protein: C639_CONCL
Sequence: MSGTTVLLLTCLFLVTMATSDCDLYDDSCTGTEICCTPPGDYQGNCMEGEDCPSGGR
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.39, O3_cal6.3.
What are the subcellular locations of this protein?
Secreted.
Protein: YCZE_BACSU
Sequence: MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLFQHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPALSTYTGSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMELTILFAAWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH
What are the official names of this protein?
Uncharacterized membrane protein YczE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADR_HAEIE
Sequence: MQNNNDILKAQSPAALAEEYIVKSIWQDVFPAGSNLPSERDLADKIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNIWDAAGPNIIETLIALDMQSAPLIIDNMLSLRSKMSESYIYEAVKNSPQKSTALFAELEQLQNTAQDYTEFDYQLFRQFTVVANKPFYRLIFNSLKGVYQRIGLLFFKEKTHRELTKQFYLEMQQICLEGNADAVVDCIRKHNLRSSTYWKAILERLPQNLSD
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_PYRAR
Sequence: MGALTIVAKYMIVAQIEVNGSVDKSDIIGALFSQTEGLLGKDMDLRELQMMGRIGRIEVDIFEKNGKTKAKIYIPSNLDRYETALVAALVESIERVGPYPASVKVIEIRDLREEKRKKIIEKAKELVKLIEEEILPDTKEIIERLKEDVAKAEVVEYGPERLPAGPDVDKSDAIIIVEGRADVVNLVKHGYRNVIALEGISRGVPQTIIDLSKKKNVTVFIDGDKGGELVLKELLKVAHVDYIARAPPGKEVEQLTAKEIAKALRNKISLEEWLAQQKASGERAEAPPQPAQQPQQEQPAPQRPIQAPFDLEKKIEEMLGTLEAEIYDQNWTLVKRLPVRELPDFLATSGDSIYAIILDGITTQRIVDLAAKKGVKVIITARTGPLTKVPEDMSIYTFEQLKKTE
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: SYFA_SHESR
Sequence: MQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQQKLTERIDGLKSAELEAKLIAEKIDVTLPGRTIDIGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEHHPARADHDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDENVNFAELKGVLHDFLRNFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB_TRITR
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEASGGKYVPRAILVDLEPGTMDSVRAGPFGTLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDNVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMTTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETFCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQGYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNNAYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATVEDEDFEEEGDYERE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YCIB_COLP3
Sequence: MQLFIEYFPLLIFFIINSIAGIYWATGSLIVAAFVQIFYYKIKKEKIPAKQWIIFGLIVVFGGLTIYLQNDAFLKWKVTIINAFFAAALLVSNTFFNKNIIKEFLAESLSLPENIWSRLNLAWALFFLFCSGLNYYIAFNYDLDTWVNFKVFGLTGLMFLFSITSILFLYKYLEVEEEINDTDTINNEKTKEST
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AJUBA_BOVIN
Sequence: MERLGEKASRLLEKLRLSDSGSAKFGRRKGESSRSGSDGTPGPGKGRLSGLGGPRKSGPRGAAGGPGDEPLEPAREQGPLDAERNPRGSFEVPRYEGSFPGGPPPSRALPLPQSLPPDFRLETTAPALSPRSSFASSSASDASKPSSPRGSLLLDGAGAGGAGGSRPCSNRTSGISMGYDQRHGSPLPAGPCLFGPPLAGVPAGYSSGGVPSAYPELHAALDRLCAHRPAGFGCQESRHSYPPALGSPGALAGAGVGATGPLERRGAQPGRHSVTGYGDCAAGARYQDELTALLRLTVGTGGREAGVRGESAGIEASGLEEPPGAFVPEAARARIREPESREDYFGTCIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKSYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECYHCEDCRMQLSDEEGCCCFPLDGHLLCHGCHMQRLSARQPPANYI
What is the function of this protein?
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.  Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton.  May be involved in signal transduction from cell adhesion sites to the nucleus.  Plays an important role in regulation of the kinase activity of AURKA for mitotic commitment.  Also a component of the IL-1 signaling pathway modulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex.  Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes.  Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription.  Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A.  Positively regulates microRNA (miRNA)-mediated gene silencing.  Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1 (By similarity).
What are the official names of this protein?
LIM domain-containing protein ajuba.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane. Cell junction. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, P-body. Note=Shuttles between the cytoplasm and the nucleus. Localizes on centrosomes during G2-M phase. Colocalizes with GFI1 in the nucleus. Preferentially colocalizes with cadherin-adhesive complexes at sites of cell-cell contacts.
Protein: NDHJ_GOSBA
Sequence: MQGRLSVWLVKHGLVHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIEYGVDQPEEVCIKVFAPRSNPRIPSVFWVWKSSDFQERESYDMLGISYENHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RPOZ_DINSH
Sequence: MARVTVEDCVDKVPNRFELVMLAAHRAREISAGSELTIDRDNDKNPVVSLREIAEETQSADALRERLIESNQTQIEVDEPEEDSMAMLMGGGQPDKPAEDDMSEEKLLRALMEAQGQP
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: FABH_STRP2
Sequence: MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRHISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVFDFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMMEYGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTC_HAEIG
Sequence: MKKYLLLALLPFLYACSNSSNQGINYDEAFAKDTQGLDILTGQFSHNIDRIWGVNELLVASRKDYVKYTDSFYTRSHVSFDEGNIVIETQQDLNRLHNAIVHTLLMGADAKGIDLFASGDVPISSRPFLLGQVVDHQGQQIANQVIASNFATYLIQNKLQTRRLQNGHTVQFVSVPMIANHVEVRARKYLPLIRKAAQRYGIDESLILGIMQTESSFNPYAISYANAIGLMQVVPHTAGRDVFAMKGKGGQPSTRYLYDPANNIDAGVSYLWILQNQYLDGITNPTSKRFAMISAYNSGAGAVLRVFDNDKDTAIYKINQMYPEQVYRILTTVHPSSQARNYLLKVDKAQKKFRVRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HSLO_YERPA
Sequence: MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_SALEP
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: ECFA1_BACCZ
Sequence: MKKEKLRTENISFQYPGAATYALKDVSFSLFEGEWVSVIGQNGSGKSTLAKLLNGLFLPEAGTITVNDTMILSEETVWDVRKQIGMVFQNPDNQFVGTTVQDDVVFGLENIGMPREQMVERLNQALRLVRMEDFLNDEPHSLSGGQKQRVAIAGVLALQPSILILDEATSMLDPQGRREVVETVRQLVNEKGITVLSITHDLEEAAQSDRVIILNKGEILEEGIPEQIFKSSHMLQEIGLDVPFSVKIAELLKRNEILLQNTHLTMESLVNELWRLHSKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSP70_ECHGR
Sequence: MMSKGPAVGIDLGTTFSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDRAVQDDIKHWAFKVINAGGKPKIEVEYRGETKCFSAEEISSMVLLKMKETAEAYLGKKVSDTVISVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVERERNVLIFDLGGGTFDVSILSIEDGIFEVKSTAGDTHLGGEDFDSRLVNHFVEEFKRKHKGKDLTTNKRAVRRLRTACERAKRTLSSSAQANIEIDSLLEGIDFYTSITRARFEELCSDLFRSTLDPVEKALRDAKLDKGAVHEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILTGDKSEAVQDLLLLDVAPLSLGLETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMKRDNNLLGKFELSGIPPGPRGVPQIEVTFDIDANGILNVSAVDKSTGKQNKITITRDKGRLSKEEIERMVNDAEKFKQEDEKQRDRVAAKNGLESYAFSMKSTVEDEKVKEKIGESDRRRIMEKCEETVKWLDGNQQAEKEEYEHRQKELESVCNPIIAKMYQEAGGVGGIPGGIPGGGMPGGTPGGGIPAGMAGGMSGDPSSGGRGPTIEEVD
What are the official names of this protein?
Heat shock cognate 70 kDa protein, HSP70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PDXJ_PELUB
Sequence: MKRLGVNIDHVATVRNARGSFHPDPFTIAKHVIKCGAHSVTIHLREDRRHIKDSDVVKICKSRKIITNLEISLNKEIIDIALKNRPNFICIVPEKRKEVTTEGGLNLIKNKKKIKSIISLFNKKSIRTSLFIDPNLKDIKIAKELNATCVELHTGKISNLIKENKSYKNEYLKIKKCSELGVKLGIEVHAGHGLDYKTTSILSKIKEITEFNIGHFIIGESLTHGLKKTITIFKEITNK
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_BUCAT
Sequence: MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKGLFIKELELALLENKADIAIHSMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLPKGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLDQGKYDAIILATEGLNRLRLKNRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLESGCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAKNILNNLHIKQSYCI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: LACB_STAAS
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: Y437_STAES
Sequence: MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQTLRLVLERAKTYSVPNHIIDRAIDKAKGAGDENYDHLRYEGFGPNGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHTATFGVEGKSVDEVLETLMEQDIDVRDVIDDNGLTIVYAEPDQFAQVQDALREAGVEEFKVAEFEMLPQTDIELSEEDQAIFEKLIDALEDLEDVQNVFHNVDLK
What are the official names of this protein?
Probable transcriptional regulatory protein SE_0437.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_COXB2
Sequence: MSTLRVLHEKSELGKTTVYPKEYAPHLLLPIPRDLNRKTLNVNVSEPPPFYGYDLWNAYELSWLNEKGKPFAARGEFIIPATSSHLIESKSFKLYLNSFNNERFADAAAVSQTMKRDLSKRVNESVTVNFILHETEIPVAYSPKGSLLDVLDIAIDTYSPDPNLLSTSQETVTETLYSHLLKSNCPVTGQPDWGSIEIHYTGPKIDHVQLLKYIISYRNHEEFHEACVERFFMDILRHCRPQELTVQARYTRRGGLDINPYRSTNPTFSVQNHRSFRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S17B3_XENTR
Sequence: MSSPDGGYASDDQIHGNCSVPIMMGQYEWTDPLTMFQDAKTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLASKRPFVEEAERLRVQHIQDYPDYKYRPRRKKQVKRMKREEEGFLPSANLAGPQVMGCNAMVGQNYKMQYSGQNSQQSQITPAGYFEDHNPVGYYYRGYNVSKYYMSQNSSGYCSPPAQGEYQALSYNFNSSYMPYQQNASTPAMGKQMAVKENIIQESPEHGIMGCQVSPQMYNGQMYVPECAKTHPVAQTEQHSSSHQSQQMVTQNYLPSQQDGHLESDIDKTEFDQYLMYEPKSDTELIYTIDQDSGAYSTNLLPSLISEANSVCYYDYCGV
What is the function of this protein?
Transcription activator.  Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'.  All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function.  In addition, the sox17 proteins have distinct but overlapping roles in later gut development.  Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly and indirectly.  Also represses wnt-responsive genes to inhibit wnt/beta-catenin-mediated signaling (By similarity).
What are the official names of this protein?
Transcription factor Sox-17-beta.3, SRY (sex determining region Y)-box 17-beta.3.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROA_PROMM
Sequence: MSVTNTASSSCELRAGGGLSGTVRVPGDKSISHRALLFGAIAEGVTTIEGLLPAEDPMSTAACLRAMGATIGPIHVGQIVRVEGVGLDGLQEPQDVLDCGNSGTTIRLMLGLLAARKGRHFVLSGDASLRRRPMNRVGQPLTMMGAKIKGRSNGDFAPLAVSGQKLRGGVIGTPVASAQVKSALLLAALTADGATTVIEPAHSRDHSERMLRAFGADLEVGGEMGRHIRVSPGQKLYGQNIVVPGDISSAAFWLVAGALVPGAELVVENVGLNPTRTGILEVLQQMEARIEVLNRHEVAGEPVGDLRVRQGSLKPFSINGDIIPRLVDEVPILAVAACFCDGESKITDASELRVKETDRLAVMTRQLTAMGADIDEHADGLTIRGGRTLRGTDLDSETDHRVAMSLAVAALLAEGNSRLTGSEAAAVSYPNFWDDLERLHR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGDP1_ARATH
Sequence: MLRPRRSLGVSSPAKQRKKAAPKNSMATRANRKRLPSYLKPGSAVEISSDEIGFRGSWYMGKVITIPSSSDKDSVKCQVEYTTLFFDKEGTKPLKEVVDMSQLRPPAPPMSEIEKKKKIVVGEEVDAFYNDGWWEGDVTEVLDDGKFSVFFRSSKEQIRFRKDELRFHREWVDGAWKPPLEETEEEEDESEEDKLDDSEDEEDILARVDLETTRAIAKQMFSSGTVVEVSSDEEGFQGCWFAAKVVEPVGEDKFLVEYRDLREKDGIEPLKEETDFLHIRPPPPRDEDIDFAVGDKINAFYNDGWWVGVVIDGMKHGTVGIYFRQSQEKMRFGRQGLRLHKDWVDGTWQLPLKGGKIKREKTVSCNRNVRPKKATEKQAFSIGTPIEVSPEEEGFEDSWFLAKLIEYRGKDKCLVEYDNLKAEDGKEPLREEVNVSRIRPLPLESVMVSPFERHDKVNALYNDGWWVGVIRKVLAKSSYLVLFKNTQELLKFHHSQLRLHQEWIDGKWITSFKSQKV
What is the function of this protein?
Heterochromatin-binding protein that preferentially occupies long transposons and specifically recognizes the histone H3 'Lys-9' methylation (H3K9me) marks, with a stronger affinity for dimethylated H3K9 (H3K9me2) (PubMed:30382101, PubMed:30425322).  Required for transcriptional silencing, non-CG DNA methylation (e. g.  CHG and CHH regions), and H3K9 dimethylation (H3K9me2) at some loci (PubMed:30382101, PubMed:30425322).  Mediates heterochromatin phase separation and chromocenter formation (PubMed:30425322).
What are the official names of this protein?
Protein AGENET DOMAIN (AGD)-CONTAINING P1, Protein ONE AGENET DOMAIN-CONTAINING PROTEIN.
What are the subcellular locations of this protein?
Nucleus. Note=Enriched in heterochromatin, concentrated in centromeric and pericentromeric regions.