PharMolix/UniProtQA huggingface dataset:
Protein: CYF_ILLOL
Sequence: MTRSISISVLIISVLIMIYVITRTSISNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPNTVFEAVVRIPYDMQLKQVLANGKRGGLNVGAVLILPEGFELAPPDRISPEMKEKMGNLSFQNYRPTKRNILVIGPVPGQKYSEIVFPILSPDPATKKEVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATGAGLVSKIVRKEKGGYEITIADASDGHQAVDIIPPGPELLVSEGEYIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL36_CORA7
Sequence: MKVRKSLRSLKKKPGAQVIRRHGKVFVINKKDPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SYH_SHIB3
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPIVDIYLVASGADTQSAAMALAERLRDELQGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVTNGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_ECO81
Sequence: MNNIWWHTKGQGNVHLVLLHGWGLNAGVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFISHPDEFCHLLVALKQRV
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCMR_STRGA
Sequence: MDSAETDTPSTRSTPNGPGLRQRKLRRTRDQLIREALELFLAQGYEHTTVEQIAEAVEVHPRTFFRHFASKEEVALTPISAIDEAFLAALEVRPAGENPLQAMSGAFRAVLGRVRDGELEGVDGALHMAMMRLVERTPGLLAEYLRRSEEMEGRLARIIAAREGVDLDDDFRPRFIVAVFKAVGRVVSREWYLRADTDLEALSVAFESALDSLRPELFADWRRPGA
What is the function of this protein?
Represses transcription of the divergently oriented tcmR and tcmA (tetracenomycin C resistance and export) genes by binding to an intergenic operator region.  This binding is inhibited by tetracenomycin C.
What are the official names of this protein?
HTH-type transcriptional regulator TcmR, Tetracenomycin C transcriptional repressor.
Protein: CASP2_HUMAN
Sequence: MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (PubMed:15073321).  Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (PubMed:15073321).
What are the official names of this protein?
Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: NU2M_DICDI
Sequence: MMFLFENSINMIKYSIYLVPLIIMILLSISIKEDSNRMMLLFKSLKLTIILILVLLTIEEAIYVKLNGHLIKTELITFVEYILLVVSYLIISMFEEGVKEGRKTKITEEALILMYSSLIGMLISMEAHNLITLFLSLEITSICFYILALNKNSRKVSIEGGLKYYIIGGIASTIILLGIVSIYKNTGSLMYTDILVIGMERIGNYQVQMGIALIVLGLIIKLGVAPFHGWLIDTYEGTGMLMTFYLTITQKIVTIIVLINLYKNLITYLNIEVINKGLLVLILVTLIVGTVGSLRQQKVIRFIAYSAIVNSALLILFFVGNNTEELIIYSIYYLINYIIGLAVLINIIIGVVKTKNGGNIEILSELKNIWLNNKVIGISLIIVLIYLAGLPPFTNFISKIILILPLIVEGKIYITMIIFFLTVGIMIYYMNVVKIIIIDKKQEVGVETYKMTKGGSITNIVGGIIWIIISQIYLDEIISIIKIIVAIN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LFTR_ECOBW
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC1_ORYNI
Sequence: MIDQYKHQQLQIGLVSPQQIKAWANKTLPNGEVVGEVTRPSTFHYKTDKPEKDGLFCERIFGPIKSRICACGNSRASGAENEDERFCQKCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKGLPSYIANLLDKPLKKLEGLVYGDFSFARPSAKKPTFLRLRGLFEDEISSCNHSISPFFSTPGFTTFRNREIATGAGAIREQLADLDLRIILENSSVEWKELEDEGYSGDEWEDRKRRIRKVFLIRRMQLAKHFIQTNVEPEWMVLCLLPVLPPELRPIVYRSGDKVVTSDINELYKRVIRRNNNLAYLLKRSELAPADLVMCQEKLVQEAVDTLLDSGSRGQPTRDGHNKVYKSLSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPLEIAIKLFQLFVIRDLITKRATSNVRIAKRKIWEKEPIVWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPTLVEGRTICLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEARLLMFSHMNLLSPAIGDPICVPTQDMLIGLYVLTIGNRRGICANRYNSCGNYPNQKVNYNNNNPKYTKDKESLFSSSYDALGAYRQKQICLDSPLWLRWKLDQRVIGLREVPIEVQYESLGTYREIYAHYLVVGNRKKEIRSIYIRTTLGHISFYREIEEAIQGFSQAYSYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSRP_NITMU
Sequence: MPIMPITPKPIRRTAFFLSDRTGITVEMLGHSLLSQFENIPLDEITLPYIDSKAKATSAVRTINERYIADEARPLVFSTLVNPEIRLIINSADALHLDCFSIFIAPLEAELGARSSENMGRSHRVSDPTGYWKRINAINYALEHDDGLSQKNWNRADVTLVGASRTGKTPTCLYLALQYGIYAANYPLIPEDFQREELPAQIRNIRSKLFGFTIHPERLHEIRSERKPESVYASLKNCEYEVQSAEKLMRRAGIPYLDATSKSIEELATAVLHEAKLERKIY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RLMG_PSE14
Sequence: MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAETGLSLQSRVLVLNDSFGALAASLASHATVVSSTDSFLAAQGLEKNLARNGMSYDAVPHIPASEPLSGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVVAAAMVKHLPRSAGDLLEEYVGPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLDEPAIELLNHANVFCRDGLDIGTRAFLPYLPKNLGTARVADLGCGNGVLAIASALDNPQAHYTLVDESFMAVQSAAENWRATLGERVVEVRAADGLDTQEPDSLDVVLCNPPFHQQQVVGDFLAWRMFLQARAALVNGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_SYNSC
Sequence: MLRSDAVTKGIQRSPNRAMLRAVGFGDSDFGKPILGIANGYSTITPCNIGLNDLAKRAEEAARQAGGMPQMFGTITVSDGISMGTEGMKYSLVSREVIADAIETACNGQSMDGVLAVGGCDKNMPGAMLAMARMNIPSVFVYGGTIKPGKLGGCDLTVVSAFEAVGQLTSGKIDEVQLTAVEKNACPGAGSCGGMFTANTMSAAIETMGLSLPYSSTMAAEDEEKADSAARSAEVLVEAVKANIRPLDLLTKEAFENAISVIMAVGGSTNAVLHLLAIARTAGVDLSIDDFERIRQRVPVICDLKPSGRYVTVDLHNAGGIPQVMKLLLDAGLLHSDCRTVEGKSLKELLADVPSEPPAGQEVIRPLSNPLYAKGHLAILKGNLASEGSVAKISGVKTPVLTGPARVFESEEDCLAAILDKKIQAGDVVVVRNEGPVGGPGMREMLAPTSAIVGQGLGDKVALITDGRFSGGTYGLVVGHVAPEAAVGGTIGLVQEGDSITVDADQLLLQLNVDQAELDRRRAGWSKPEPRYRSGILGKYARLVSSSSRGATTDHAD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PETG_CYAM1
Sequence: MVEILLSGIVLGLIPITILGLLMAAYFQYQRSKAAS
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS8_HUMAN
Sequence: MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S8, Small ribosomal subunit protein eS8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: MVP_MYMVV
Sequence: MENYSGAVVNNKYVETKSCEYRLTNNEMPIKLQFPSYLEQKTVQIMGKCMKVDHAVIEYRNQVPFNAKGTVIVTIRDTRLSYEQAAQAAFTFPIACNVDLHYFSSSFFSLKDETPWEIVYKVEDSNVIDGTTFAQIKAKLKLSSAKHSTDIRFKPPTINILSKDYTEECVDFWSVEKPKPIRRMLNPGPNQGPYPISGHRPIMLQPGETWATRSSIGRSSSMRYTNNDRPSILDNTSASDADYPLRHLHKLPEASLDPGDSVSQSHSNAMSKREIEDIIETTISKCLISQRSNVNKAL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Begomovirus genome is shuttled out of nucleus by Nuclear shuttle protein (NSP) and the movement protein transports the DNA-NSP complex to cell plasmodesmata and facilitates further movement across the cell wall (By similarity).
What are the official names of this protein?
Movement protein BC1, Movement protein BL1.
What is the protein family that this protein belongs to?
Belongs to the begomovirus movement protein BC1 family.
What are the subcellular locations of this protein?
Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host microsome membrane; Peripheral membrane protein; Cytoplasmic side. Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found on ER-derived vesicles.
Protein: DCMC_HUMAN
Sequence: MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKTPAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAAVLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNGVLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFFSHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQGVELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSECKEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVANFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQVLSLVAQFQKNSKL
What is the function of this protein?
Catalyzes the conversion of malonyl-CoA to acetyl-CoA.  In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced.  In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids.  Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling.  May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.
What are the official names of this protein?
Malonyl-CoA decarboxylase, mitochondrial, MCD.
Protein: OLFA_LITPI
Sequence: MIRIIAIVVLFFLQCQADLPPVMKGLEENKVTGVWYGIAAASNCKQFLQMKSDNMPAPVNIYSLNNGHMKSSTSFQTEKGCQQMDVEMTTVEKGHYKWKMQQGDSETIIVATDYDAFLMEFTKIQMGAEVCVTVKLFGRKDTLPEDKIKHFEDHIEKVGLKKEQYIRFHTKATCVPK
What are the official names of this protein?
Olfactory protein.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_YARLI
Sequence: MSVEERPVIFDDQSELPKVFVGGRKSKLALVQTQHVAAMLKKVHPDYSFPVLGLTTLGDQVQSKPLYSFDGKALWTKELETLLLEKVPGFDQQDIIVHSLKDMPTVLPDGCELGAILTREDPRDALVMAAGSPYKTLADLPAGSVVGTSSIRRSAQLKKSYPGLVYESVRGNVGTRLSKLDDPETPYKCLILAAAGLKRLDLGDRITGYLQKPDMLHAVGQGALGLEIRQGDEKTKKILEAIYDKESTLCCLAERAVMRTLEGGCSVPIGVETKYENGKLTLDAIVVSVEGTEFVECTQVRAVEENWEAEQLGKDVAEQLVKDGAKKILDAIHLENIK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SPEB_ECOL6
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDIIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: RF1_ACIBT
Sequence: MKASLRLRLDQLCDRHEELTALLADAEVISDNKRFRKLSREHSDLTEITEVWGKYRQAEEDIETAEMMKSDPDFKDMAEEEIQANKALLEELESQLNILMIPKDPNDSNAAYLEIRAGTGGDEAAIFSGDLFRMYSKYAESQGWRIEVLSENEGEHGGFKEVICRVDGDGVYGRLKFESGAHRVQRVPATESQGRVHTSACTVAILPEIDVDTNVEINPADLRIDTYRASGAGGQHINKTDSAVRITHIPTGTVVECQEERSQHKNKAKAMALLVSRLENAKRAAADAATSEMRRDLVGSGDRSERIRTYNYPQGRMTDHRINLTLYKLDAIMEGDLTELLDSLHREYQADQLAMLAQENGG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_ROSDO
Sequence: MTHGRVNPDFRLEDQGITGLGTVYYNLIEPDLIQYALARGEGSLGKGGSFLVTTGKFTGRSPKDKHVVKTDSVADTIWWENNREMSPEGFDQLYTDMLAHMEGRDYFVEDLTGGSDPKHAINVRMVTELAWHGLFIRHMLRRPDREDLDDFIADFTVINCPSFQADPAKHNCRSETVIAMNFDKKLILIGGTEYAGENKKSVFTLLNYLLPEKGVMPMHCSANHAVGNPVDTAVFFGLSGTGKTTLSADPARTLIGDDEHGWSDTGTFNFEGGCYAKTISLNPEAEPEIYATTEKFGTVIENMVYDAETKDLDFEDDSLTANMRCAYPLHYISNASQAARGGHPKNIIMLTCDAFGVLPPISRLTPAQAMYHFLSGFTSKVAGTERGVTEPEPTFSTCFGAPFMPRRPEVYGNLLREKIATHGATCWLVNTGWTGGAYGTGSRMPIKATRGLLTAALDGSLADAEFRKDPNFGFQVPVDVTGVPGILLDPRRTWDDAEAYDRQAAKLVKMFSDNFEQYLPFIDEDVRAAAIS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHE_HAEIG
Sequence: MSIKILSESEIKQVANSYQAPAVLFANPKNLYQRRAKRLRDLAQNHPLSDYLLFAADIVESQLSTLEKNPLPPQQLEQLNAIEPLNTKTFKRDSIWREYLTEILDEIKPKANEQIAATIEFLEKASFAELEEMANKLLTQEFNLVSSDKAVFIWAALSLYWLQAAQQIPHNSQVENTENLHHCPVCGSLPVASIVQIGTSQGLRYLHCNLCESEWNLVRAQCTNCNSHDKLEIWSLNEELALVRAETCGSCESYLKMMFQEKDPYVEPVADDLASIFLDIEMEEKGFARSGLNPFIFPAEEA
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SULNB
Sequence: MTMIRMTRMGRKKKPFYRIVVTDSRKRRDGGWIEAIGHYNPVSENKELTLDEERLNYWLSVGAQMSPTVKRLAGKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: COX3_CHOCR
Sequence: MTTLSQISKSVQRHPFHLVDPSPWPFVASLCAFSCAIGGVMYMHAYVNGSFILSISFFCLLLVMFTWWRDVIRESTFEGHHTGIVQQGLRFGVILFIISEILFFFAFFWAFFHSSLAPTIEIGSIWPPKGINVLNPWEIPFLNTLILLLSGCTVTWCHHSLVSNLRNQSVLSLFLTIVLAIVFTTFQAYEYSMADFRLSDGIYGSTFYMATGFHGFHVLVGTISLAVCLIRLLQYQLTQQHHFGFESAAWYWHFVDVVWLFLFVSIYWWGGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FCL_AZOC5
Sequence: MGKGKKLLITGGRGMVGRNLIACAARSGWEIIAPTSVDLDLRNAEAVEQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSFRSEVVTLINLSSSCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPNFNYKTLIACNLYGVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAYDFAKIIIKALEVPELIPSSMNVGVGKDLSVLEYYSLVARVIGWSGEFVYDLNRPVGMRSKLMDITHLTALGWVPERSLEGGIRSTYQYYITGNEVYE
What is the function of this protein?
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
What are the official names of this protein?
GDP-L-fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase, Nodulation protein NolK.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Protein: RL362_NEIM0
Sequence: MQVLSSLKTAKQRHRDCQIVRRKGKVYVICKSNPRFKARQR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ISPF_SYNP6
Sequence: MSRFRIGNGYDIHRLVEGRPLILGGIQLEHSLGLDGHSDADVLTHAIMDALLGALSLGDIGHYFPPTDPQWKGADSLKLLAQVNQLIRDRGWTIGNLDSVVVAEQPKLKPHIAAMRDRLAKVLELEPDQIGIKATTNEKLGPTGREEGICAYAVALLVRD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.