PharMolix/UniProtQA huggingface dataset:
Protein: RSAKS_PSESP
Sequence: MSRFIRASQRRTLLATLIAATLAQPLLAAESLDSKPASAITAAKNAEVLKNLPFADREEFEAAKRGLIAPFSGQIKNAEGQVVWDMGAYQFLNDKDAADTVNPSLWHQAQLNNIAGLFEVMPKLYQVRGLDPANMTIIEGDSGLVLIDTLTTAETARAALDLYFQHRPKKPIVAVVYSHSHIDHFGGARGIIDEADVKAGKVKVFAPSGFMEHAVSENILAGTAMARRGQYQSGVMVPRGAQAQVDSGLFKTTATNATNTLVAPNVLIEKPYERHTVDGVELEFQLTLGSEAPSDMNIYLPQFKVLNTADNAPPAMHNLLTPRGAEVRDAKAWAGYIDASLEKYGDRTDVLIQQHNWPVWGGDKVRTYLADQRDMYAFLNNRALNLMNKGLTLHEIAAEVSKLPGELDRKWYLRSYYGALSTNLRAVYQRYLGFYDGNPANLDPFPPVEAGKRYVEAMGGADAVLKQMRAAIDKGDYRWAVQLGNHLVFADPANKDARALQADAMEQLGYQTENALWRNMYMTGAMELRHGVPTYDSRGKSEMGRALTPDMFFDLLAIRLDTDKAVGHDMTLNWVFEDLKQDIALTLRNGVLTQRVGSLNPKADVTVKLTKPTLDQIAARKLDLPTAIKQGTVKLDGDGKKLGEFFGLLDSFSPKFNIVEPLE
What is the function of this protein?
Alkylsulfatase that catalyzes the enantioselective hydrolysis of secondary-alkylsulfates with strict inversion of configuration, leading to the formation of homochiral (S)-configurated alcohols and nonreacted sulfate esters (PubMed:21770430, Ref. 2, PubMed:23061549).  The substrate spectrum includes a range of linear, branched or cyclic sec-alkylsulfates (PubMed:21770430).  Can use sec-alkylsulfate esters bearing aromatic, olefinic and acetylenic moieties (Ref. 2).  Acts by cleaving the C-O bond, resulting in inversion at the carbon (PubMed:23061549).
What are the official names of this protein?
(R)-specific secondary-alkylsulfatase, (R)-specific sec-alkylsulfatase, Inverting sec-alkylsulfatase Pisa1, Inverting secondary alkylsulfatase 1, Type III (R)-specific secondary-alkylsulfatase.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.
Protein: Y1459_MYCTU
Sequence: MAARHHTLSWSIASLHGDEQAVGAPLTTTELTALARTRLFGATGTVLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFTLGRRRMSRGKLDRTLLLWMLPLLIAPPMYSKDVYSYLAQSEIGRDGLDPYRVGPASGLGLGHVFTLSVPSLWRETPAPYGPLFLWIGRGISSLTGENIVAAVLCHRLVVLIGVTLIVWATPRLAQRCGVAEVSALWLGAANPLLIMHLVAGIHNEALMLGLMLTGVEFALRGLDMANTPRPSPETWRLGPATIRASRRPELGASPRAGASRAVKPRPEWGPLAMLLAGSILITLSSQVKLPSLLAMGFVTTVLAYRWGGNLRALLLAAAVMASLTLAIMAILGWASGLGFGWINTLGTANVVRSWMSPPTLLALGTGHVGILLGLGDHTTAVLSLTRAIGVLIITVMVCWLLLAVLRGRLHPIGGLGVALAVTVLLFPVVQPWYLLWAIIPLAAWATRPGFRVAAILATLIVGIFGPTANGDRFALFQIVDATAASAIIVILLIALTYTRLPWRPLAAEQVVTAAESASKTPATRRPTAAPDAYADST
What is the function of this protein?
Catalyzes the addition of alpha-(1->6)-mannose residue.
What are the official names of this protein?
Alpha-(1->6)-mannopyranosyltransferase Rv1459c.
What is the protein family that this protein belongs to?
Belongs to the MptA/B family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: GELS_MOUSE
Sequence: MAPYRSSLLCALLLLALCALSPSHAATTSRGRAQERAPQSRVSEARPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLGYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLKVLRSQHVQVEEGSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDNYWSVDPLDRALAELAA
What is the function of this protein?
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping).  It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (By similarity).  Plays a role in ciliogenesis (By similarity).
What are the official names of this protein?
Gelsolin, Actin-depolymerizing factor, ADF, Brevin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm, cytoskeleton. SUBCELLULAR LOCATION: [Isoform 1]: Secreted.
Protein: HOIL1_RAT
Sequence: MDEKTKKAEEMALSLARAVTGGDEQAAIKYATWLAEQKVPLRVQVKPEVSPTQDIRLCVSVEDAYMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPSLQQWVVGQRLARDQETLHSHGIRRNGDSAYLYLLSARNTSLNPQELQRQRQLRMLEDLGFKDLTLQPRGPLEPVLPKPRTHQETGQPDAAPESPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQIPASYQPDEEERARLAGEEEALRQYEQRKQQQQEGNYLQHVQLEQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHERMNCREYQDDLAHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
What is the function of this protein?
E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates (By similarity).  Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination (By similarity).  Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome (PubMed:18303026).  Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation (By similarity).  LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways (By similarity).  Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation (By similarity).  LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex (By similarity).  The LUBAC complex is also involved in innate immunity by conjugating linear polyubiquitin chains at the surface of bacteria invading the cytosol to form the ubiquitin coat surrounding bacteria (By similarity).  LUBAC is not able to initiate formation of the bacterial ubiquitin coat, and can only promote formation of linear polyubiquitins on pre-existing ubiquitin (By similarity).  The bacterial ubiquitin coat acts as an 'eat-me' signal for xenophagy and promotes NF-kappa-B activation (By similarity).  Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis (By similarity).  Binds polyubiquitin of different linkage types (By similarity).
What are the official names of this protein?
RanBP-type and C3HC4-type zinc finger-containing protein 1, Heme-oxidized IRP2 ubiquitin ligase 1 homolog, HOIL-1, Protein kinase C-binding protein beta-15, RBCC protein interacting with PKC, RING-type E3 ubiquitin transferase HOIL-1, Ubiquitin-conjugating enzyme 7-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
Protein: GCSH_AGRRK
Sequence: MLKFTEEHEWLNIEGDVATVGITAHAAGQLGDLVFVELPEVGASFSKGDDAATVESVKAASEVYCPLDGEITEINEAITADPELVNSDPMGAGWFFKLKLKNVADADGLLDESGYKELIG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ENDUB_XENLA
Sequence: MEANRGQVNHELSKLFNELWDADVNRMKAGKDYRISLQGKAGYVPARSNQAKDSASYPLFQFVDEEKLKSKKTFATFISLLDNYEMDTGVAEVVTPEEIAENNNFLDAILETKVMKMAHDYLVRKNQAKPSQNDFKVQLYSIWFQLYSRAPGSRPDSCGFEHVFVGESKRGKEMMGLHNWVQFYLQEKRKNIDYKGYVARQNKSRPDEDDQVLNLQFSWKEMVKPVGSSFIGVSPEFEFALYTIVFLASQAKMSREVIRLEEYELQIVVNRHGRYIGTAYPALLSTNNPDLY
What is the function of this protein?
Poly(U)-specific endoribonuclease involved in the processing of intron-encoded box C/D snoRNAs, such as U16 and U86.  Releases products that have 2',3'-cyclic phosphate termini at the 3'-end.
What are the official names of this protein?
Poly(U)-specific endoribonuclease-B, Protein endoU-B, Uridylate-specific endoribonuclease-B, XendoU-B.
What is the protein family that this protein belongs to?
Belongs to the ENDOU family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZNT8_XENLA
Sequence: MKGPEKAYLVSDKATKMYSLTMDSSEKNNCGKPPLQDDENPHIKYHCHNNNTKAYDARQREQTSAKKKLCIASLICFVFISAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLGSLWLSSKSSTMRLTFGWYRAEILGALMSIITIWLVTGVLVYLAIERIIRPDYTIDGTVMLITSACALGANVVLALILHQSGHGHSHAGGKHEHMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKIADPICTFIFSIFVLITTVTVLRDLLNILMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVILSAHIATDILGESKRILKDVTQNVCSSFPFHSVTIQVEPVEEQSPECMFCYEPTQ
What is the function of this protein?
Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion.
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A8, Solute carrier family 30 member 8, Zinc transporter 8, ZnT-8.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Protein: SYQ_EDWI9
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGLCNLRFDDTNPVKEDIEYVESIKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLAYVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEKMRLGEFAEGSACLRARIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRRGYSAAAVREFCRRIGVTKQDNNVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAADSVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANKQYKRLVLGKEVRLRNAYVIRAERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSVANPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVFNRTVGLRDTWAKAAL
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_POLCR
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIESVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVVLLRDDFVEKDRSRGIYFTQDWVSIPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVRARNEGRDLAREGNEIIREASKWSLELAAACEVWKEIKFDFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXB_ECOLC
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLYDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPZ_DICDI
Sequence: MLSMIKQQGAAADSRRGQALLLNISAGKGLQNVLKTNLGPRGTLKMLVGGGGDIKLTKDGKVLLHEMQIQHPTAALIARTATAQDDITGDGTTTNVITIGELLKQSERYLQENIHPRIIAEGFELAKDRCLAFLEEFKQTSQDTLDRELLISIAKTSLRTKLPADLADQLTEQVVDALLLIHKPEQPLDLFMVEIMTMQHRTDGHCSLIKGLVLDHGTRHPDMPKKLTNCFILTCNVSLEYEKTEVNANFLYKDHETRSRMIDGEHKLVAAKCRQIIELKNHVCDTPDKNFVVINQKGIDPICLDMLAKAGIMGLRRAKRRNMERLTLACGGTAMNSLEDLTPDCLGHADLVYEQTLGEEKYTFVEGVKNPFSCTVLIKGPTKHQIEQIKDALRDGLRAVKNTIEDKCVVPGGGAFQIAAYADLMKFKETITGRTKLGIQAFADALLVVPKTLAQNSGFDPMDTIIKLQEEYAKGHIVGLDVESGEPMDPVSEGIFDQYSVLKQVYRSSPVIASQLLLIDEIIKAGKGMRGSSVPEGQE
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit zeta, TCP-1-zeta, CCT-zeta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_PORG3
Sequence: MEMLQIAGKTFESRLFVGTGKFASSDLMEAVVLASQSRMVTVALKRVEIGRGEEDDMISRIVRHPEITLLPNTSGVRSAKEAILAAELAREALQTNWLKLEVHPDPRYLLPDPIETLRATEELVRRGFIVLPYVQADPVLCKHLEEAGAATVMPLGAPIGSNRGLKTREMIRIIIEQSRVPVVIDAGIGAPSQAAEAMEMGADAVLVNTAIAVAEDPVSMATAFRLAVEAGRMAFEAKLGSVRSEAEASSPFTSFLNLK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBM_PROM0
Sequence: METTNFGFVASLLFVGVPTIFLIGLFISTQDGEKSSFYSDSSKGRLGPKR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: IACI_PESFW
Sequence: MSLLDLPTLWNASGVEALDSDLFEYFCCVASGSLPTFGHDATALRNILVRTALEGETASAAAVLQALLAFSSLHRYGLQPQALELKITALGSLAKGSFTPGLGTKETIEHIAAGMLLSSFEVHQSSCTSGHWTGYLGGVKTITDMSSVKTLLQFSSDVAVLLDWVHYHNVLARFSLLYWNGEETSEFPSTPTNLLSSQDSSLPPPIYSMMDLLSQICDLSNSAIPTGTSDEVDNYKGFLKVLDWRIRSLPIKGDNDGEMLLMKLYQLALLLFLNRSFEGLIDQPIRMQQQIGQAFAILPRLSSCRQQFPIYVIGCEARTDEQRAAVLDLITKTEKMSTSRSFNHCRTLLQAVWTQDDLAEWDDISYRAKLTLVISRCAVAPIFV
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of iso-A82775C, a enylepoxycyclohexane and biosynthetic precursor of the chloropestolide anticancer natural products.
What are the official names of this protein?
Transcription factor iacI, Iso-A82775C biosynthesis cluster protein I.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZKSC7_HUMAN
Sequence: MTTAGRGNLGLIPRSTAFQKQEGRLTVKQEPANQTWGQGSSLQKNYPPVCEIFRLHFRQLCYHEMSGPQEALSRLRELCRWWLMPEVHTKEQILELLVLEQFLSILPGELRTWVQLHHPESGEEAVAVVEDFQRHLSGSEEVSAPAQKQEMHFEETTALGTTKESPPTSPLSGGSAPGAHLEPPYDPGTHHLPSGDFAQCTSPVPTLPQVGNSGDQAGATVLRMVRPQDTVAYEDLSVDYTQKKWKSLTLSQRALQWNMMPENHHSMASLAGENMMKGSELTPKQEFFKGSESSNRTSGGLFGVVPGAAETGDVCEDTFKELEGQTSDEEGSRLENDFLEITDEDKKKSTKDRYDKYKEVGEHPPLSSSPVEHEGVLKGQKSYRCDECGKAFNRSSHLIGHQRIHTGEKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPYKCNECAKAFTQSSRLTDHQRTHTGEKPYECNECGEAFIRSKSLARHQVLHTGKKPYKCNECGRAFCSNRNLIDHQRIHTGEKPYECSECGKAFSRSKCLIRHQSLHTGEKPYKCSECGKAFNQNSQLIEHERIHTGEKPFECSECGKAFGLSKCLIRHQRLHTGEKPYKCNECGKSFNQNSHLIIHQRIHTGEKPYECNECGKVFSYSSSLMVHQRTHTGEKPYKCNDCGKAFSDSSQLIVHQRVHTGEKPYECSECGKAFSQRSTFNHHQRTHTGEKSSGLAWSVS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 7, Zinc finger protein 167, Zinc finger protein 448, Zinc finger protein 64.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL2_HAHCH
Sequence: MPVVKTKPTSPGRRHVVAVTNPSLHKGAPLASLTEKKRKNGGRNNAGRITVRHQGGGHKQLYRVIDFKRTKDGIPAVVERLEYDPNRTAHIALLKYADGERRYIIAPKGVSVGDAIASGQEAPIRVGSCLPLRNIPVGSVVHCIEMKPGKGAQIARSAGASAQVVAREGAYATIRLRSGEMRKVLVECRATLGEVSNSENNLRVYGKAGAKRWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVPTKGYKTRKNKRTDKMIVRRRKAK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ULAD_ESCF3
Sequence: MSLPMLQVALDNQTMASAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: TRMD_EHRCJ
Sequence: MTLNVNVLTIFPEMFPGPLSYSVIGRALNKGIWNLNVIDIRSFAKDKHKTVDDKPYGGGPGMIMKADVIGSAIDEVLSKNKNTKLIYMSPSGVKLNQDISGQLTHFSNITVLCGRFEGIDKRILDFYDFHEISIGDYILSGGEVACMVLIEACVRLIPGVVNNTQSICDESFTLNNQLEYPQYTRPAKWRGLEVPDILLSGNHKKINLWKANQSYCITKQRRPELTDTINGDIYE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTNLB_ARATH
Sequence: MADEHKHEESSPNLDPAVEVVERESLMEKLSEKIHHKGDSSSSSSSDDENEKKSSSSSPKSLKSKVYRLFGRERPVHKVLGGGKPADIFMWKDKKMSGGVFGGATVAWVLFELMEYHLLTLLCHVMIVALAVLFLWSNATMFIHKSPPKIPEVHIPEEPLLQLASGLRIEINRGISSLREIASGRDIKKFLSAIAGLWVLSILGGCYSFLTLAYIALVLLFTVPLFYDKYEDKVDSYGEKAMAELKKQYAVLDAKVFSKIPRGPLKDKKKD
What is the function of this protein?
Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus.
What are the official names of this protein?
Reticulon-like protein B2, AtRTNLB2, VirB2-interacting protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UBIA_COXB2
Sequence: MINLRQQMPHYLRLMRFDKPVGIFLLLWPTLWAVWIAAKGAPSFKIAVIFIAGSVVMRAAGCIVNDFADRHLDKHVQRTQMRPLASGSVSVTEAMLLFAVLSLIAFTLVLLLNRLTVELAVIGILLALVYPFLKRFTHLPQLWLGVAFSWSIPMAFAATVGHVPAVAWLLFFAAVLWPIVYDTQYAMIDREDDVKVGIKSTAILFGRYDRLMIGLLQGSVLLTFGLLGWYLRFNYWFYLGLLVALGLMCYQQFLIRHRKPPDCFAAFRNNNWVGFFIFLGILLTYRN
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADM_THEVO
Sequence: MQSTKEHRAFLIGRFQPFHLGHLEIVKRILRENDSIIIGIGSAQYSHTTVNPFTAGERHLMISRTLEREHVYNYYLVPIEDVNANSLWVSHVEALAPKFDVVYTNNPLVRRLFTEKHYEVRSLPMVNRSEWTGTKIREKMIKGENWEQNVPEPVVEVIREIDGISRIRQLSTTDEDVP
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAXB1_MOUSE
Sequence: MTSFQEVQLQTSNFAHVIFQNVAKSYLPNAHLECHYTLTPYIHPHSKDWVGIFKVGWSTARDYYTFLWSPMPEHYVEGSTVNCVLAFQGYYLPNDDGEFYQFCYVTHKGEIRGASTPFQFRAASPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTLKEKEELLKLIAVLEKETAQLREQVGRMERELSQEKGRCEQLQAEQKGLLEVSQSLRVENEEFMKRYSDATAKVQQLEEDIVSVTHKAIEKETDLDSLKDKLRKAQHEREQLECQLQTEKDEKELYKVHLKNTEIENTKLVSEIQTLKNLDGNKESMITHFKEEISKLQSCLADKENLYRALLLTTSNKEDTLFLKEQLRKAEEQVQATRQELIFLTKELSDAVNVRDKTMADLHTARLENERVKKQLADTLAELQLHAVKKDQEKTDTLEHELRREVEDLKLRLQMAADHYREKFKECQRLQKQINKLSDQAASTNSVFTKKMGSQQKVNDASINTDPAASTSASAVDVKPAASCAETGFDMSTKDHVCEMTKEIAEKIEKYNKCKQLLQDEKTKCNKYAEELAKMELKWKEQVKIAENVKLELAEVEDNYKVQLAEKEKEINGLASYLENLSREKELTKSLEDQKGRKLEGQSPQQVSRCLNTCSEQNGLLPPLSSAQPVLQYGNPYSAQETRDGADGAFYPDEIQRPPVRVPSWEDNVVCSQPARNLSRPDGLEDPEDSREDENVPIPPDPANQHLRSHGAGFCFDSSFDVHKKCPLCELMFPPNYDQTKFEEHVESHWKVCPMCSEQFPPDYDQQGFERHVQTHFDQNVLNFD
What is the function of this protein?
Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation (PubMed:18239685, PubMed:33207181).  Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates.  Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production (By similarity).  Recruits also A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways (PubMed:18239685).  Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling (By similarity).  As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis.  Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation (By similarity).
What are the official names of this protein?
Tax1-binding protein 1 homolog.