PharMolix/UniProtQA huggingface dataset:
Protein: ATG1_ASPFU
Sequence: MTSTHHSRRSRETPQPEMSIGRYTRLDEIGRGSFATVYQGVHTKTRTYVAIKSVNLSKLNKKLKDNLSSEIHILKGLYHPHIVALIDCHETTSHIHLVMEYCALGDLSLFIKRRDTLGDHRYTRDMIAKYPNPPGGALNEVVVRHFLKQLASALKFLRDRNLIHRDIKPQNLLLCPSPSSYRSGVTQVVPFKGSEDSFNPATGLESLPLLKIADFGFARSLPATSLAETLCGSPLYMAPEILRYEKYDAKADLWSVGTVLYEMVVGKPPFRATNHVELLRKIEKGEDRIKFPEENPASDEIKALIRALLKRNPVERLNFPDFFQNGVITSPIPGLVADDLPSIPQGPPADPETAEATPRPDSRSGATVPGGTEREREGPSLPKGDTGLTQRPPSQNQRFGTPQTTTPMRRIGSGDRPPSTPKESTPPMTYPQRPSAVSHATAPGRQELVDRNATFTAMERQKGRNTFSEGSPQIDRQADKLREERERAAQDVAFERDYVVVEKRAVEVNAFADELAHSPRIQGNISRGAQTGALSRRSTVHGPTPSNPSPPQATVGKAMQVLSGRSRADSMHNRQGSYERRYGQSPTSATSAISKALNMASGRLFGMGFSPPLAITKGGRSPPLAYNPFPAYPAHGSLMIGDGAKSNLALDEDTKTVQILEECATRSDVVYGFAEVKYKQLVPLAPSVQTDPSSKLNLAGERENPDSADGGLTVDAIVTLSEEALVLYVKALSLLAKSMDIAGAWWARKNRGDGFGDSAMSRANGASTLAGTRINNVVQWIRNRFNEVLEKGEFVRLKLIEAQKRLPPDHPSHPDNHSVGSSLGSGASVDVVVSPGVSAEKLMYDRALEMSRTAAINELTGEDLSGCEIAYVTAIRMLEAVLENGEVPRFGQDKDDTSKDSDKIVLDAVQADERQVVIKLLTIQAVVASIRSRLAALRKKLAILAKRAPTPSANVPSKMASSNPVSVGATPPK
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase atg1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: HPLN4_MOUSE
Sequence: MACAPGALGHRALWAVAWGLLLLVPVLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDVGMVKLDLEGVVFPYHPRGGRYKMTFVEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVSHAREPCGGTGSTGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV
What is the function of this protein?
Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs (PubMed:22121037).  Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons (PubMed:30125937).
What are the official names of this protein?
Hyaluronan and proteoglycan link protein 4, Brain link protein 2.
What is the protein family that this protein belongs to?
Belongs to the HAPLN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: USPB_ECO57
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_SYNY3
Sequence: MGIRNYRPMTPGTRQASVSDFTEITKSKPEKSLTTNRHDQKGRNNRGVITSRHRGGGHKKLYRIIDFKRNKQNIPARVAAIEYDPNRNARIALLFYTDGEKRYILAPAGLQVGMTVIAGEEAPFEIGNTLPLSRIPLGSEIHNVELVAGRGGQMVRSAGAFAQVVAKEGDYVTIKLPSKEVRMVRKECVATLGRVSNAEFRNLKLGKAGRKRHLGRRPHVRGSVMNPCDHPHGGGEGRAPIGRSGPVSPWGKPALGAKTRNKKKRSSALIVRRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RM40_YEAST
Sequence: MSGSYQHLSNVGSRVMKRLGNRPKNFLPHSEKFIKKSTPEFMKSDLKEVDEKTSFKSEKEWKFIPGDRVVVMSGASKGNIAVIKSFDKRTNSFILDENGPTKTVPVPKQFWLEGQTSHMITIPVSILGKDLRLVADIDDEKTPGKTRTVAVRDVSFNGSYYDADYKKVMPYRCVKGQPDLIIPWPKPDPIDVQTNLATDPVIAREQTFWVDSVVRNPIPKKAIPSIRNPHSKYKRGTLTAKDIAKLVAPEMPLTEVRKSHLAEKKELAEREVPKLTEEDMEAIGARVFEFLEKQKRE
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L40, mitochondrial, Mitochondrial large ribosomal subunit protein uL24m, YmL40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CAIA_SALPA
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTH_ARATH
Sequence: MALKLFLFALLLCLPTSLSSTASKGKEKKSKFNPYRYTFIDKASTFSSSSSSSFSSNGQDSSYDYIVIGGGTAGCPLAATLSQNFSVLVLERGGVPFTNANVSFLRNFHIGLADISASSASQAFVSTDGVYNARARVLGGGSCINAGFYSRADAAFVKRAGWDPKLVKESYPWVEREIVHQPKLTLWQKALRDSLLEVGVRPFNGFTYDHVSGTKIGGTIFDRFGRRHTAAELLAYANPQKLRVLIYATVQKIVFDTSGTRPRVTGVIFKDEKGNQHQALLSNRKGSEVILSSGAIGSPQMLMLSGIGPKKELQRLKIPVVLENEHVGKGMADNPMNTILVPSKAPIEQSLIQTVGITKMGVYVEASTGFGQSPESIHTHYGIMSNKNELFSTIPAKQRRPEATQAYITRNKYQLHEAFNGSFILEKLAYPISRGHLSLVNTNVDDNPSVTFNYFKHPVDLQRCVEAIRLVSKVVTSNRFLNYTQCDKQNVHKMLSLSVKANINLRPKQLNDTKSMAQFCKDTVVTIWHYHGGCLVGKVVSPNRKVLGVDRLRVIDGSTFDESPGTNPQATMMMMGRYMGVKILRERLGNKAGV
What is the function of this protein?
Probable FAD-dependent enzyme.  Involved in regulating post-genital organ fusion.  Required to limit cellular interactions between contacting epidermal cells during floral development.
What are the official names of this protein?
Protein HOTHEAD, Protein ADHESION OF CALYX EDGES.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: FMT_XANCP
Sequence: MRIVFAGTPDFAVASLRAAAQRHEVVAVYTQPDRPAGRGRGLTPSPVKLDAIARGIPVFQPQTLRSPEALATLRALQPDLMVVVAYGLILPKAVLAAPTHGCWNVHASLLPRWRGAAPIQRAIEAGDTETGVCLMQMEAGLDTGPVLLSQRVEIGEQETGGQLHDRLAALGAQVLSDGLGLLRAGIRPVAQPQPAEGVTYAHKLDKAQARLDWAQPAEELARRVRAFNPWPVAEAILAGERVRLHGAVALDLAHQQAPGTLLAASKQGIDIACGQGALRVRVLQREGGKAITAADYLNARRDLPALR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NCAP_EBOG4
Sequence: MDSRPQKVWMTPSLTESDMDYHKILTAGLSVQQGIVRQRVIPVYQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYKLFLESGAVKYLEGHGFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAMPEEETTEANAGQFLSFASLFLPKLVVGEKACLRKVQRQIQVHAEQGLIQYPTAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVAQARFSGLLIVKTVLDHILQKTQRGVRLHPLARTAKVKNEVNSLKAALSSLAKHGEYAPFARLLNLSGVNNLEHGLFPQLSAIALGVATAHGSTLAGVNVGEQYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNEISFQQTNAMVTLKKERLAKLTEAITAASLPKTSGHYDDDDDIPFPGPINDDDNPGHQDDDPTDSQDTTIPDVVVDPDDGSYGEYQSYSENGMNAPDDLVLFDLDEDDEDTKPVPNRSTKGGQQKNSQKGQHTEGRQTQSRPTQNIPGPHRTIHHASAPLTDNDRRNEPSGSTSPRMLTPINEEADPLDDADDETSSLPPLESDDEEQDRDGTSNRTPTVAPPAPVYRDHSEKKELPQDERQDQDHTQEARNQDSDNTQPEHSFEEMYRHILRSQGPFDAVLYYHMMKDEPVVFSTSDGKEYTYPDSLEEEYPPWLTEKEAMNEENTFVTLDGQQFYWPVMNHKDKFMAILQHHQ
What is the function of this protein?
Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response.  VP35 binds to and stabilizes monomeric NP, keeping it soluble.  Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released.  The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication.  The nucleocapsid is helical with a pitch of 10. 81 NP per turn and a diameter of about 22nm.  Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid.  Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription.  Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1.
What are the official names of this protein?
Nucleoprotein, Ebola NP, eNP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the filoviruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RPOE_STRAW
Sequence: MAHGEVLEFEEYVRTRQDALLRSARRLVPDPVDAQDLLQTALVRTYGRWDGIADKRLADAYLRRVMINTRTEWWRARKLEEVPTEQLPDASVDDSTEQHADRALLMDILKVLAPKQRSVVVLRHWEQMSTEETAAALGMSAGTVKSTLHRALARLREELESRDLDARALEREERERCAA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with cell wall-related functions (By similarity).
What are the official names of this protein?
RNA polymerase sigma-E factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_GEOSM
Sequence: MEQLVYIALLGALGCLCRYFLSGLVYQVFGTSFPYGTLAVNLIGAFLIGLVMEFSVRSAAIPPTLRFAITIGFLGGLTTFSTFSFETFRLLEDGALLIAFVNVLVSVVACLTCTWIGIMVARAL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYVM_SCHPO
Sequence: MFHFQRSFSSRKAHGLLSFKNRNYIHIEAPFDIAAIQDGWNIIRKHIHYPKPKSIEAPMFPILLPPPNITGKLHIGHALTITIQDALARFYAMHGYKVSFRPGTDHAGIATQSVVEKYLQKKGVYRNQLSKDELLSSIHSWQVKYQKSIINQLKSFEAIFDWDNIFYTMDQNRSEAVNEAFISLFNAGLIYRANRFVNWCPKLESAVSDIEVESQQINKPVTKYVDNTPVEFGWLYEISYQLEGSDNEQLNVSTTRPETIFGDRAIAVSPHDERYKKYVGRFVKHPLIDDLLIPVICDNAVDRHFGTGVLKITPMHSIVDYEIAKRHNIDCVSIMDKSGNLINCSKEVNGMNRLKARSKIVRLLQQRNRLVEQVPHSLILSVCSRTGDVIEPVMVPQWYLSVDSLKKEVLKSSNKLKLVPSLARKEWDSWFKKMGDWCISRQIWWGHQIPVWKILEEDKWIAAPNYEKALQLSVGKSVSQDSDVLDTWFSSALLPLSAFGWPKSKDIQPLPFIESGQDILFFWIARMALLCKYFSNELPFKEIILHPLVRDSEGRKMSKSLGNVIDPMDIINGVTLENMKKALLEGNLPISEVHKSSKQMEKAFPNGIPAQGIDIFRYGLFLCLHHEQRILLDMNSFSDAHRFVSKLWNLARYFNQYKDKENPLKLTDSQRQRISLLKMATYSKLHHAVEGVKESFEQRKFFNAADIMKNFLLNDLSSVYVELTRFDVKDSKSSAYEVYRVFSDILHIFLKLIHPIVPCISGVMLHSKIIPERKNSEFLSFPTSQQECLLVHDNQAEVVVQNAYDVLIQLRKLESPLNKSPSREHTVYISTSLEPLKYFYDAIEQSTNLKLKSISQEDTIDLMRNQTFILSRISSDTILLVPKKLYPSKRKKLRKNLDDLQKKLDKIQHTTSSSGYEKAPSYIKLKNCELQKDILVKIQDIKQALLNTEI
What are the official names of this protein?
Valine--tRNA ligase, mitochondrial, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZNUC_BRUAB
Sequence: MDKKSSHPAGAARDILIELRNAGVYRDGRWLVRNVDLSVERGEIVTLIGPNGAGKSTAAKMALHILKPDEGMVSHKPGLRIGYVPQKINIDRTLPLSVERLMTLTGPLPRKEIDAALEAVGIAHLAKAETAHLSGGEFQRALMARALARKPDIMVLDEPVQGVDFSGEAALYELIARLRDDTGCGVLLISHDLHLVMAATDRVICLNGHVCCSGTPRDVTSSPEYVRLFGSRAVGPLAVYEHHHDHTHLPDGRVLYADGTTADPIAGSTMGPRGHCHVEDGHHHDHEHHHHEGGQPRA
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TEKT5_MACFA
Sequence: MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGYRYLNSWRPSLFYKISNVQTCPDESSSTLRPPTTLPALRSALFSRYSPHDWDQSNQLQVRGAEASRLWASRLTDDSVRLLQDKDQLTQQMQQGTTRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQQQMRKLAQRIDLQMRDNRDAQHALERDLDDKSSAQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRADSIRLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTWRPNVELCRDVPQFKLVNEVFTIDDTLQTLKLRLRETQDMLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGHT
What is the function of this protein?
May be a structural component of the sperm flagellum.
What are the official names of this protein?
Tektin-5.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Appears to be associated with flagellar accessory structures and not the axoneme.
Protein: RM41_RAT
Sequence: MGFLTAVTQGLVRGADRMSKWTSKRGPRTFTKSRGAKKTGFYTNRKFVQIKEMVPEFVVPDLTGFKLKPYVNYRAPAGIDTPLTAKALFLETVAPAIEKDFKEGTFDANNLEKYGFEPTQEGKLFQLYPKNFPR
What is the function of this protein?
Component of the mitochondrial ribosome large subunit.  Also involved in apoptosis and cell cycle.  Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition.  Enhances p53/TP53 translocation to the mitochondria.  Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
What are the official names of this protein?
39S ribosomal protein L41, mitochondrial, L41mt, MRP-L41.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CAS2_HALVD
Sequence: MQVIVVYDVPAKRTRIYRKLLRRRLEHLQYSVFFGELTAGQVTAMKNEIESELEPTDSIVVFEFDNPHAFDHTTFGDADEPGSRFT
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.  Plasmid targeted by CRISPR locus P1 transform wild-type cells very poorly (PubMed:22767603).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: ACDH1_CUPNH
Sequence: MDMKASGHHKVAIIGSGNIGTDLMIKVMRHGRSLEMGAMVGIDAASDGLARAARLGVPTTAEGIDGLVGMPGFGDIRIAFDATSAGAHAHHNRVLQQHGVRVIDLTPASIGPYVVPVVNLDQHLDAPNINMVTCGGQATIPMVAAVSRVARVHYAEIVASISSRSAGPGTRANIDEFTETTSQALCSVGGAARGKAIIVLNPAEPPLMMRDTVFTLSEDGDEAEIAASVEAMAQAVQGYVPGYRLKQRVQFERIAASAPLNIPGLGPMSGLKTSIFLEVEGAAHYLPAYAGNLDIMTSAALACAERLAETRLSA
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: IF1_DESPS
Sequence: MAKEEAIEVEGTIIEPLPNAMFRVELDNGHKVLAHISGKMRMHFIKILPGDRVTVELSPYDLTRGRVTFRTKNTKKKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSJ_THET2
Sequence: METRTLEDWRALLEAEKTLDSGVYNKHDLLIVRGQGARVWDAEGNEYIDCVGGYGVANLGHGNPEVVEAVKRQAETLMAMPQTLPTPMRGEFYRTLTAILPPELNRVFPVNSGTEANEAALKFARAHTGRKKFVAAMRGFSGRTMGSLSVTWEPKYREPFLPLVEPVEFIPYNDVEALKRAVDEETAAVILEPVQGEGGVRPATPEFLRAAREITQEKGALLILDEIQTGMGRTGKRFAFEHFGIVPDILTLAKALGGGVPLGVAVMREEVARSMPKGGHGTTFGGNPLAMAAGVAAIRYLERTRLWERAAELGPWFMEKLRAIPSPKIREVRGMGLMVGLELKEKAAPYIARLEKEHRVLALQAGPTVIRFLPPLVIEKEDLERVVEAVRAVLA
What is the function of this protein?
Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine (Probable).  In vitro, can use N(2)-acetyl-L-ornithine and N(2)-acetyl-L-lysine (PubMed:11489859).
What are the official names of this protein?
[LysW]-aminoadipate semialdehyde transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BIFLO
Sequence: MGSQLALKSRIRSTESLAKIFNAQEMIASSHIAKARDVALNAKPYTDAIFDAVQALVAHTHITHPIAVKDEKNPRVAVLALTSDRGMAGPYTSSIIRETESLLSRLDAAGKQPELFVYGRRGSTYYKYRNRDIAATWEGDTDQPGVEIAETISNTLMDAYMKPAEKGGVSELYIVYTEFINMVVQKVRVLRMLPVEIVKNETKVPDPDEEAPATADVAPLYTFEPSLEKVLDAILPKYIQSRIHECLLTAAASETASRQNAMHTATDNARNLIDDLTRKLNASRQASITQELTEIIGSADALTKKEE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PCRB_STAAR
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHLYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: TRUB_MYCGA
Sequence: MDFNNKIVIIDKPKNISSAFCLNLFKKRFNIKKAGHNGTLDPLASGVLVVATNKRTKELSQLNQDDKQYLVKLKFNTHTDSYDRLGKVIRTTNYVPEIKQLNDYLTSLDNHSFYQLPPNFSALKVNGVRAYQLARKAVDFELEKRPTTIYKAKLISYYDDYAEILLDVKKGFYVRSFVVDLASQFNTTAMMVDLVRTRSGQYSLKDVIDYQFNK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: DRDI_CLOBM
Sequence: MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEDVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFKNFFKYLKEKSAYLDSSRPTAVNLSWALKIMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKAIGENLVTLLKDGVGILTHCNAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCDRIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDIDTKTGKDIPIEERNPEEVTSRFGVWTAPRGVKVYNPGFDVTPHENITAIVTEKGIVYPPFEENLKKLFEK
What is the function of this protein?
Catalyzes the isomerization of 5-deoxy-alpha-D-ribose 1-phosphate to 5-deoxy-D-ribulose 1-phosphate, as part of a 5-deoxyribose salvage pathway that recycles this toxic radical SAM enzyme by-product to mainstream metabolites.
What are the official names of this protein?
5-deoxyribose 1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the EIF-2B alpha/beta/delta subunits family. DrdI subfamily.
Protein: SECB_GLAP5
Sequence: MAEENQVATEEQQTPFEMQIQRIYIKDVSFEAPNLPNIFHQEWKPQLGFDLDTETREIGEDTYEVVLHINVQTTLEDSNDVAFICEVKQAGVFTIKGIEGIQLAHCLAAKCPEVLYPYARELISSLVNRGTFPALNLSPVNFDALFMDYLARQQAEENGESTTNTTLN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_SALG2
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKEGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDEALSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFVAAQGHSVGKSLYEADLVDEAKRLLTTCDIPVPTDVRVATEFSETAPATLKSVNDVKEDEQILDIGDASAQQLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.