PharMolix/UniProtQA huggingface dataset:
Protein: PNP_POLNS
Sequence: MTMFKKAVKSFQWGTYQVTMETGEIARQAGGAVIVNVDDTVVMGTVVASKSAKPGQSFFPLTVDYLEKTYAAGKIPGGFFRREGRPSEGETLISRLIDRPLRPLFPEGFLNEVQVVVHVLSINPDVPSDIPALIAASAALAVSSIPFAGPVGAARVGYANGQYLLNPTRTEQATSELDLIVAGTQAAVLMVESEANQLSEEVMLGAVVYGHDQMQTAINAINDLVCEAGKPEWDWTAAPKDEPFIAKVTALAEAPLREAYQIRQKGARSDKLKEISKEVMAKLSEEGDVDAVAVSDIMFEIEAKIVRSQILNGEPRIDGRDTRTVRPIEIRNGVLPRTHGSALFTRGETQALVVATLGTARDEQIIDVLEGEYRDRFMFHYNMPPFATGETGRVGSPKRREIGHGRLAKRALIPVLPSAEDFAYSIRVVSEITESNGSSSMASVCGGCLAMMDAGVPVKAHVAGVAMGLILDGNRFAVLTDILGDEDHLGDMDFKVAGTANGITALQMDIKVQGITKEIMQVALAQAKEGRLHILSKMQEAMGSVRTELSAHAPRMVSFKIHPDKIREVIGKGGATIQALTKETGCSIDIKDDGTVTIASTSAEGMAEAKARIEGITAEAEVGKIYEGPVVKLLEFGALVNILPGKDGLLHISEISNERVKEVKDYLAEGQVVRVKLLAADERGRLRLSLKAAMADEGGTIAPLAGAAEVATEAAPATGESA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_LIMRJ
Sequence: MDFYQTSLSQLHDDLVNKKISATELTKETFDHIKGNEDQVKAFISLNEDQALKRAAEIDAKGISADQLTAGVPLAVKDNILTKGLTTTAASKMLENFNPVYDATVVEKLNAADYINVGKTNLDEFAMGSSTENSAFFTTHNPWDLTRVPGGSSGGSAAAVAAGDVLGALGTDTGGSIRMPASFNGVVGMKPTYGRVSRWGIIAFGSSFDQVGWLTQNVKDNALLTALISGNDERDMTSSLKEVPDWAAQLNENTNVKGLRIAVPKEYFDGLDEDVQEVIKAALDHLESLGAIVDEVSLPHTKYGVPAYYILASSEASSNLQRYDGIRYGFRAADVKNLEDVYVRSRSEGFGEEVKRRIMLGTFSLSAGFYDAYFNKAAKVRRLIAQDFEDVFKDHDVIVGATGASTAFKIGAEIDDPQTMYMNDVLTVPVNMAGLPAMSIPAGFSAKNGMPVGLQIIGKAFDEQTVYNTGYVFEQTTDFHKKTPKLGGQN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: VPB29_MYCTU
Sequence: MRTTIDLPQDLHKQALAIARDTHRTLSETVADLMRRGLAANRPTALSSDPRTGLPLVSVGTVVTSEDVRSLEDEQ
What is the function of this protein?
Possibly the antitoxic component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC29.
What are the official names of this protein?
Putative antitoxin VapB29.
Protein: SYN_SORC5
Sequence: MQDQPVIATSDLSAHVGSTVVLRGWLYNKRSSGKLHFLELRDGFGTVQCVMAKSDVGDEVFAAADKVTQESVIDVVGEVKAHPKRAGVYEIAASGFRVLGPTAGEYPISPKEHGTDFLMDHRHLWLRSKRQHAILRVRHTIIQAIRDFFDGRGFTLVDAPVFTPNACEGTSTLFQTDYHGEKAYLTQSGQLYMEAAAAAFGKAYCFGPTFRAEKSKTRRHLAEFWMVEPEVAFMDLAGDMDLAEDFLCFIVERVLERRRPELAVLERDVGKLEAVKKPFPRIRYDEAVAILNEARAEKRKMAGEAEIPDFPWGEDFGGEDETIISGRYDRPVMIHRYPAQVKAFYMKRDPTDDRLALCVDVLAPEGYGEVIGGGQREDDLATLERAIEAHQLPPEAFGWYLDLRRYGTFPHAGFGLGVERSVAWICGLPHVRETIPFPRMLNRLSP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_RHOPA
Sequence: MIPGELFIEDGEIELNAGRKTVTLTVSNTGDRPIQVGSHYHFFETNPALKFDRDKARGMRLDIAAGTAVRFEPGQSRDVQLVELAGKRTIYGFRGDVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_PIPCE
Sequence: MTKRYWNINLEEMMEAGVHFGHGTRKWNPRMAPYISAKRKGIHITNLTRTARFLSETCDLVFDAASRGKHFLIVGTKSKAADLVALAAIRARCHYVNKKWLGGMLTNWSTTETRLHKFRDLRAEQRAGKLNCLPKRDAAMLKRKLSHLQTYLGGIKYMTGLPDIVIIVDQHEEYTALRECITLGIPTICLIDTNCDPDLSDISIPANDDAIASIRLILNKLVSALCEGHSSYIRNR
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INP4B_PONAB
Sequence: MEIKEEGASEEGQHFLPTAQASDPGDCQFTSIQKTPNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTGVTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDSPPEIGRSFLGYASFKVGELLKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHITTDIQGQKCALVCECTAPESVSGKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSFKSSSSKGDKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHSPDSLKNSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSPQDQPPLMRGQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERDGGSEGSGGNNDGEKEPSLADAIPSHPREDWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDVVFSQALAGLVCGFIIKLQTSLYDPGFLRQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAFKIIEAKSNDVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQNIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT
What is the function of this protein?
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate (By similarity).  Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (By similarity).  Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (By similarity).
What are the official names of this protein?
Type II inositol 3,4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type II.
What is the protein family that this protein belongs to?
Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.
Protein: RPFC_XANCP
Sequence: MKSPLPWLKRRLSGRADSEHAQNLIRIIITTLFISYLGWRYQHTHGDTLMATWLILVGELLVSLGLMVAILLRPQVSHTRRLIGMLLDYTCTGAIMAIQGEPASPLYAVCMWVTIGNGLRYGSNYLRAATAMGSLCFLGAILISPYWKANPYLSWGLLLGLIAVPLYFDSLLRAMTRAVREARHANQAKSRFLANMSHEFRTPLNGLSGMTEVLATTRLDAEQKECLNTIQASARSLLSLVEEVLDISAIEAGKIRIDRRDFSLREMIGSVNLILQPQARGRRLEYGTQVADDVPDLLKGDTAHLRQVLLNLVGNAVKFTEHGHVLLRVTRVSGSAEDAVRLRFDVEDTGIGVPMDMRPRLFEAFEQADVGLSRRYEGTGLGTTIAKGLVEAMGGSIGFKENQPSGSVFWFELPMAIGEPLKSSTVRVPTGALVDAPEELESSNIIAFSNPFLRHRARVRSMRMLVADDHEANRMVLQRLLEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDLHMPGMNGLDMLKQLRVMQASGMRYTPVVVLSADVTPEAIRACEQAGARAFLAKPVVAAKLLDTLADLAVSTRQLATPATTVQVATSFEGVLDSSVLDELAALGMGEEFERQFVRQCLDDAQNCVGDIERDGTCSDWEQLRESAHALRGVASNLGLAQVASSGGELMRMADWQLQAEWRLRLSTLREQLKAGKDALDARVQGVKDGECSPRSNE
What is the function of this protein?
Hybrid sensor kinase that regulates diverse biological functions through two distinct molecular mechanisms (By similarity).  At low cell density, the extracellular concentration of the diffusible signaling factor (DSF) is below a threshold, and unphosphorylated RpfC is involved in the negative regulation of DSF synthesis, via direct interaction with the DSF synthase RpfF.  Interaction prevents synthesis of DSF, which remains at a basal level.  This activity does not involve the phosphorelay mechanism and is not dependent on RpfG (PubMed:20826346).  Is also member of the two-component regulatory system RpfG/RpfC, which is involved in the perception and response to DSF, which is essential for cell-cell signaling (By similarity).  At high cell density, the level of extracellular DSF increases and binding of DSF to the sensor region of RpfC causes autophosphorylation of RpfC, which results in the release of RpfF and the activation of RpfG via a four-step phosphorelay (By similarity).  Activation of RpfG leads to the positive regulation of biofilm dispersal and the production of virulence factors (By similarity).
What are the official names of this protein?
Sensory/regulatory protein RpfC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes at the cell poles.
Protein: TOLB_WOLWR
Sequence: MKLFVHLVLFISLFIPYFTKAALYVDIKKSSVGNIGLVVSKCTCKTALESELSENIAKVIGTNLSNCGLFNVKRGAEAESKSWKSDTVVTVSLSEISGSALELSFRLFDTFTKRELLTQSVVFPAKDWRKIGHLVSDVIHDRLIGEKGHFNTKITYIAEEKDSNYKSVRKIAVMNQDGSNIKYLTNGDRFVSTPRFSPNGKGIVYISYANGKSYIILKNLKDNTESIISTFEGVVSAPRFSPDGKSLLISHSLGGETNILSLDLSSKRTKKITKGSAISTSPSFSPDQKYMAFSSDISGSQQLYVIDFTNKSKKPKRISFGSGRYATPVWSPKGDLIAFTKIQSGKFYIGVMKPDGKEERLLSEGHKIESPAWLPNGREIIFTRTESPSNSKLYLVDLVKKNQKMVSTPTNASLPDWSYF
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: METXA_METFP
Sequence: MKKESVGVVETKHYNLSEELILDGGDSLKDVTIAYETYGTLNKQKSNAILVCHALSGNAHVAGWHEGDRKPGWWDNIIGPGKCLDTDRYFIICSNVLGGCQGSTGPSSLNPETGKQYALEFPIITIKDMVKAQKKLIDHLQIKQLFSVVGGSMGGMQVLQWCVSYPDMVRSAIPIATTSYSSPQQIAFNEVGRRAIISDPHWNEGNYYEGEFPDSGLALARMIGHITYLSNESMYEKFGRRLQDKEEYSFDFSTDFEVESYLHYQGDTFTKRFDANSYLYISKAIDYFDLTENGTVSLSEALKNVKARVLVISVDSDWLYTPAESKEIVMAMTANEVDVSYCQIKSSYGHDAFLLEAGQLSYIINGFFSETLVVDVMTIHAATITEDSSIEEAAELMLDEKVTHLPVVSEDYRMLGIVTAWDISKAVALKYDKLDQIMTRDVVTALPQDPIELAARKMRKHNISSLPVVNDQGNVLGLITTDHISTLIAGDKY
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_DESHD
Sequence: MYPDLSQRQTDILEYIKRVIREKGYPPSVREIGDAVGLMSSSTVHGHLQTIEEKGYIRRDPTKPRAIEILDSSSDANEKKTVFVPIIGKVTAGQPILAQENIEDTFPLPVDVVNSDTVFMLRVKGESMIDAGIMDGDLILVRQQKVARNGEIVVAMIDEEATVKRFYKEKTLIRLQPENPYMEPIYSQDVTILGKVIGVFRILH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CB21_CUCSA
Sequence: PTLAGQAVKLSPNAPEIQGNAKFTMRKTASKSVSSGSPWYGPDRVKYLGPFSGEPPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCVFPELLSRNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWACQVVLMGAVEGYRIAGGPLGEVTDPIYPGGSFDPLGLADDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein of LHCII type I, chloroplastic, CAB, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PUR9_MYCLE
Sequence: MSSDGERDMARKPIRRALISVYDKTGLIDLAQGLNAAGVDIVSTGSTAKAIADQGIAVTPVEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIEAFELVVVNLYPFSQTVKSGATVDECVEQIDIGGSSMVRAAAKNHPSVAVVTDPLGYVGVLAAVQGGGFTLAERKMLASMAFQHIAEYEIAVASWMQSTLAPEQPPTAFPQWFGRSWRRSAILRYGENPHQQAALYSDPSACPGLAQAEQLHGKNMSYNNFTDADAAWRAAFDHEQSCVAIIKHANPCGIAISSLSVADAHRKAHECDPLSAYGGVIAANTEVSLEMAEYVSTIFTEVIVAPSYAPGAVDVLSCKKNVRVLVASAPLRGGSELRPVSGGLLIQQPDQLDTAGDNPANWTLATGSPAGPATLTDLVFAWRACRAVKSNAIVIAADGATIGVGMGQVNRVDAARLAVERGGDRVRGAVVASDAFFPFADGLQTLAAAGVTAIVHPGGSVRDAEVTAAATKAGVTLYLTGVRHFVH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: R7BP_HUMAN
Sequence: MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling.  Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes.  When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits.  When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling.  May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
What are the official names of this protein?
Regulator of G-protein signaling 7-binding protein, R7 family-binding protein.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Lipid-anchor. Note=Shuttling between the plasma membrane, the cytoplasm and the nucleus is regulated by palmitoylation.
Protein: YWRF_BACSU
Sequence: MYIFQADQLSAKDTYKLLSGTVIPRPIAFVTTLSSGGAVNAAPFSFYNVVSSDPPLLSISVNRTEGRQKDTARNAVENGEFVVHVSDEAIIEDINETAASLRPDESELTRTSLHPVESKAVSVPGIKEARVRFECKLERHITFDNDQGITTADLLIGRVVCFHLDEKVYDAEKGYILTDELKPASRLAGNHYAKLGEEFTLIRPS
What are the official names of this protein?
Uncharacterized protein YwrF.
What is the protein family that this protein belongs to?
Belongs to the flavoredoxin family.
Protein: CD8B2_HUMAN
Sequence: MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMCIYWLRQRQAPSSDSHHEFLTLWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPVTLGLLVAGVLVLLVSLGVAMHLCCRRRRARLRFMKQFYK
What is the function of this protein?
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets.  CD8 is thought to play a role in the process of T-cell mediated killing (By similarity).
What are the official names of this protein?
T-cell surface glycoprotein CD8 beta-2 chain, CD8b pseudogene.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UXAB_ECOUT
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQYRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: Y3322_SHEB8
Sequence: MLDTKFDELMDFPCAFPFKVVGEAHETLTDKVVAVVQKHAPGDYSPSTKTSSKGSYHSITIRVTVTSKDHIEILYTELAAIEGVRRVL
What are the official names of this protein?
UPF0250 protein Shew185_3322.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: CLAE_PASFU
Sequence: MSLSRSVAAMHFPVTAPPPVPVPHAPHTGGLHEATATASSSAGPTSTSIAAGPRVRSSCETCAASKLKCSKERPRCARCVKRGLDCTYVLLKRAGRKPGQPQTSSRSRRREPSSGGPSPPSGVTGTSTSSDMLQDLFGTPLDMTVDGFDAAMSDSSTFHSSDLLDDHSLSAFTADPFFIHGLDDQQLHSICDDDPHSMLGVPPLMNHALMEPRTPRALSISDNGSQHLRTGRLDGVSCSCLARVLSLFQRYSASSESLCMHQRKPELDERLENVSTQSILSQNGTAVELLSGILESPCCQDGYLVVMVALVTFKILGWYSAVAQRTKTLLPGERHNPSPSFDEQHSNTTTTIRGFCLDGEDSERRTVQLILGELHPVRQLIERFALRLKLLVEEMQDADKAGVAAKDLCANAMLSTSTLVYKQLETDLRSEWRALSARVIDRLKNL
What is the function of this protein?
Transcription factor involved in regulation of the gene cluster that mediates the biosynthesis of cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress.
What are the official names of this protein?
Cladofulvin biosynthesis regulatory protein claE, Cladofulvin biosynthesis cluster protein E.
What are the subcellular locations of this protein?
Nucleus.
Protein: WGRTX_GRARO
Sequence: MKAQIFVVVLGLAALSVLCYGSEADESALHEEIFQLLAASDEVPKPQERDCVRFWGKCSQTSDCCPHLACKSKWPRNICVWDGSVGK
What is the function of this protein?
Inhibits P/Q- (Cav2. 1/CACNA1A) and N-type (Cav2. 2/CACNA1B) voltage-gated calcium channel by modifying voltage-dependent gating (PubMed:9415720, PubMed:29483648).  It selectively and reversibly blocks the calcium channels coupled to glutamate release (PubMed:8848236).  Also inhibits potassium channels (Kv2. 1/KCNB1) with lower affinity (PubMed:9671721, PubMed:29483648).  Has also been shown to weakly inhibit Kv11. 1/KCNH2/ERG1, Kv1. 2/KCNA2, Kv1. 3/KCNA3, Nav1. 5/SCN5A, Nav1. 7/SCN9A and TRPV1 (PubMed:29483648).
What are the official names of this protein?
Omega-theraphotoxin-Gr1a, Omega-TRTX-Gr1a, Omega-grammotoxin SIA, Omega-GTX SIA, Omega-GrTx SIA, Omega-GsTx SIA.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 07 (GrTx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_THERP
Sequence: MARERIPITREGLEALRQEYEYLVKHRRPEIARVIQEAREHGDIRENAAYDAAKHDQAFIEGRIREIEELLKRVELIEQPTDGDRSVVRVGSTVTIEIDGEIETYTIVGAIEAKPSAGRISNESPVGRALLGHRAGEIVPIETPNGTLMARIIEVQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ACKA_CLOB8
Sequence: MKVLVINCGSSSLKYQLIDMSNEESLAQGLVERIGITGSILTQKVEGKDKYVVETPLKDHQDAIELVLKCLVDENHGVISSMDEISAVGHRVVHGGEKYATSVVINEEVIKALDEFTKLAPLHNPPNIIGINACKALMPKTPMVAVFDTAFHQTMPEKAFMYALPYELYTEDHVRRYGFHGTSHKYVAGEMAKLMNKDISDLKIVTCHIGNGVSITAVDGGKSVDTTMGFTPLDGIIMGSRSGSIDPAIVTYLVKEKGYSIDEVNDILNKKSGVLGISGIGTDFRDIRSAVENDNDPRALLTMDIFGYQVKKQIGAYAAVMGGVDAIVFTAGIGEHAPEIRSRALTNMEFLGIEVDLEKNESHNIGDGMEISKETSKVKVVVIPTNEELMIAKETLELVK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGKH_DROGR
Sequence: MSNFLKPNTLHVDSLSPRHRSLSSGLSSGLSSACSSGSVSPVPIIPIIAISRIRDGDESESESEIELEPARIFHRRMSINNSGNNKRSTNLASIIKEGYLLKHTWSFQRWRRRYFRLKRNHLYYAKDAKCDVFDEIDLSELCYFECSIKNVNHSFQIITPTRSVVLCADSRRDMEDWLGSLKAATAPQRPRGDSILIDQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKAIANCKWTTLATVGKDIIEQPDGSIIMPHQWMEGNLPVSSICAVCKKTCGSVLRLQDWRCLWCRDTVHVACRPQMAIACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAISVPKIPKMSITTEQEAVLTGMVTAANQHLRLIVETNDTQTLISSTRNLCDTIDDLVSRIFEHHKDDEQLAVKCDILKQKLTMLLDALQEEEIGAHSGDDLIATIRSLIARSVPSTNSARPSLLNPNISIEKTEKDHINLKERRSSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKIPTNSGESTPCSSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVPEVIQELEEGANGETIYRIGRLSLSGGANIDDAGNRLSPVSDGGDNSPIDRKLDFLRVPIITSDSIVDPLSDYRPIEVFERTYYMARELDKDKDKERKQDVVLDGEKEEDAGVNEKCEEQTLHPQNTLVHTCNLQVPGIVVTPQSQNVYTSDSITIIDTDQQSNTLQEQSSSEELGCDASDVLSAISNEECSVASEIFDKAETGHTLGDIIQNLDASNFTHIDSPETSDETEAMPGESLMDDISSVLGHDITNALQDNTITDDTTTLCSEHMGPPKPPRKKSMSALSKSQIHPRRRNSSPPRMARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLECNSNNNSNNNSNSNSNNNNHNDGNSNDEPETPTNTVITLAHSQLTTTSTSDELDELSTQTAIKIEIHDADSSTMCTTTATTKPLESAMASSTSPTKRSGLGQDISVVVRPPTPLRGDSIKPTPSSSSILSSSLLGVRSLNSSEIRRHSSHAPSLAVREYDKDKDRRHSGFNPNYLALDPEHARFLSSSPAASRRISCGSLFKKNQKYYTKRTYGLFRVRFFVVAEPDIRLATLALIRPLIPLPNEALPNLQTLKGSKSSLFMGSTLFGFEHFSDKEERQGKDKERTPPEETSRKMPIINPIVRLPNWPNLANGTGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSTKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLEVSLKSWQEKQRQHSISIQRDASSTASEHAVSTDDVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQQFKPPMTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN
What is the function of this protein?
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
What are the official names of this protein?
Diacylglycerol kinase eta, DAG kinase eta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCI_ECODH
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_MYCBP
Sequence: MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDSLVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.