PharMolix/UniProtQA huggingface dataset:
Protein: RS19_YERPY
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPIRTWSRRSTVFPNMIGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: THIG_CAMJJ
Sequence: MQENLKNDKLKIGKYEFDSRFILGSGKYSLELIKSAIEEAKAQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNADEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDAGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGSPSQACEAMQMGVSAVMVNTAIAEAKDIALMAKAFSLAVNAGRAAFLAGLASVSKAKASSPLTGFLRD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_SHESM
Sequence: MSDAKELKQVLTGPIVNNNPIALQVLGVCSALAVTSKLETALVMALALTAVTAFSNLFISMIRNHIPSSVRIIVQMTIIASLVIVVDQLLQAYAYQISKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLAVGFVRELFGNGSLFGVQILHKISEGGWYQPNGLLLLPPSAFFLIGILIWIIRTYKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_BORBU
Sequence: MSIISPQDVKKLREETNAGFGDCKKALSVAGGDFELAKKKLREMGIASAEKRLDRDAKEGRVFSYSNNIYAGLLLVSCETDFVALNHNFVNFGNSLIKELVESGIDSLTTSQELELKNLAATIKENIQVKKIFITKIQSNEFVKIYLHGEQSKIGVLVKLKVNDFSKTEDKIFKNFAMDLALHVAAFAPVYLRNDDVCPNYIKEQEEIFTKQLESSGKPESIIKGIVAGKIKKHLAEISLLEQSFVKNDKITVKEMLEEISKAISSKVEMVEFKYLRIG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CHLPD
Sequence: MKQDLHPKYTKVTVNCANCGNSFETRSTRPSIKVDICNNCHPFYTGKQMLVDTAGRVERFNKRFAKSTAAQAKAQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ISPH_DESDA
Sequence: MNVRRAKTAGFCMGVSLALQKLNTALERRAGQSAGAGRICTLGPIIHNPQVLAEYETRGVVCVNDPAQLRQDDVAVIRAHGITRQVEQAVCASGATVVDATCPKVKKAQLSIARATSQGATLLLFGEEDHPEVRGLISYACGPAHVFGNAVELAALPLDPAQPYVLASQTTQDREIFTSIQESLSRALDDLTILSTICDATRERQEEARNIASSVDVMVVVGGRQSGNTRRLADVAALNGIATYHVESAEELEPKNFANKPRVGLTAGASTPKSLIDAAEKWLSSL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RECR_RICPU
Sequence: MNETNDNDIDQLIYLFSKLPGLGIRSARRIALYLLQDKDVRLKSLINNLVEIDKKIVKCEICGNMDTENICRICSSEYRDKSIIAIVETVAELWAMERSGNFKGLYHVFGHNLSAASRQNPSILRLPELLTRCFAENIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDDGTVSAAINLRQPFE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: THIO_METTM
Sequence: MVVKIEVFTSPTCPYCPMAIEVVDEAKKEFGDKIDVEKIDIMVDREKAIDYGLMAVPAIAINGVVRFVGAPGREELFEAISDEIE
What is the function of this protein?
Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase.  May be a component of a ribonucleotide-reducing system distinct from the previously described systems utilizing thioredoxin or glutaredoxin.
What are the official names of this protein?
Probable Thioredoxin, Glutaredoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOJAP_CHRVO
Sequence: MEIQEISKLAIEALEDIKGKDIIELDTSKLTSLFQRMIVATGDSNRQVKALANSVQVKLKEAGVDIVGSEGHESGEWVLVDAGDVVVHVMLPAVRDYYDIEALWGGQKPSFAVGAAKPWSAV
What is the function of this protein?
Functions as a ribosomal silencing factor.  Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8.  Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
What are the official names of this protein?
Ribosomal silencing factor RsfS.
What is the protein family that this protein belongs to?
Belongs to the Iojap/RsfS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHXD_BACSU
Sequence: MSDSNLTNPIKAFFHDEFPEQYQEPPGLQKNMKPVPDCGEKSYKGSGKLTGRKALVTGGDSGIGRAAAIAYAREGADVAINYLPEEQPDAEEVKELIEAEGRKAVLIPGDLSDESFCQDLVKQSHHELGGLDVLALVAGKQQAVENIEDLPTEQIYKTFEVNVFSLYWVVKAALPYLPEGASIITTTSVEGYNPSPMLLDYAATKNAIIGFTVGLGKQLASKGIRVNSVAPGPIWTPLQISGGQPTENIPKFGQGTPPAPLNRAGQPVELADVYVFLASENSSYVTSQVYGITGGIPTA
What are the official names of this protein?
Uncharacterized oxidoreductase YhxD, ORFY.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y182_SYNY3
Sequence: MTQAQAKRFQFDRQLWHRFVETAQPYFYPVGQKQTRVFLGLILALMVVVVALTLFLSMGLTLWATAIFPDFFAKSGEGLVDGVQGLINSPAPWIGLVALAMAGAVFISQRQKLQQRWLQWLLLGVLLSLLFVVNGLNVILSFVFRFIDTALNGKDAEVFWQFLWIYGIVIVVAIPIIVAYRYLRQKLGVLWRQWLTEHFLGRYFKGRSYYHLDSNSAYTLIDNPDQRITQDIQSFTGVTLDFLLDILDSILTLISFTAILYTISQTLMWGLIGYAVFGTVVAIAIGTRLIRINYEQLRLEANFRYGLVRVRDNAESIAFYRGEGLERKQVTDRLLGAIRNFNLLIIWQALISLFQLGYNYFTRLIPYIIIAPLYLAGDLDFGAIAQASLAFGMVLSALSLVTNQIQNITEFAASINRLGEFYESLNGPSNELERPESTGFDHNVITTRIGATVALENVTLSPPNSSRILVRDLSLAVAPGNHLLIMGPSGSGKSSLLRAIAGLWDSGQGTIERPELADLLFLPQRPYMILGTLREQLIYPSAQSIADDDFLLETLNKVNLPDLAERFGGLDSLENWSSVLSLGEQQRIALARVFINQPRYAILDEATSALDVNNEAELYHALTDLGTTFISVGHRPTLRNFHRQCLEVQAEGRWQISPINN
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein sll0182.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_RICFE
Sequence: MKVIFMGTPEFAVPALKKLITHHEVKAVFAQQPKAKGRGLNLAKSPIHQLAFEHQIPVYTPSTLRNDKTINLINKINADIIVVIAYGFIVPKAILEAKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDAGLDTGDILMKEDFDLEERTTLEELHNKCANLGAELLIKTLANIDNIVPIKQSSDGVTYAHKLTKEEGKINWYESAYKIDCKIRGMNPWPGAYFSYNDKIIKILEAEYLNAEHHFTSGTVISDKLEIACGSGILRVKKLQQESKKALNIEEFLRGTNILKDTILK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TCR_STREE
Sequence: MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRDF
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYV_CHLTR
Sequence: MNEDQFPKAYDPKSSETGVYSFWERSGMFVANASSEKPAYSIVMPPPNVTGILHMGHALVNTLQDTLIRYKRMQGFEVCWVPGTDHAGIATQTVVERHLKASLGKQRTDFSREEFLKHVWDWKEKSQNVILSQLRQLGCSCDWSRQRFTMDPGANRAVKKAFKILFDKGVIYRGYYLVNWDPILQTALADDEVEYEERDGWLYYIRYQVVNSEEFITVATTRPETLLGDTAIAVSPEDLRYSHLIGAKVVVPFVNREIPIIGDFSVDASFGTGAVKITPAHDKDDYKTGMNHQLPMINILTPTGEINENGGIFTGLSREVARENIITSLEALGLFVKKEAYSSRVGVSYRSGAIIEPYLSKQWFVSVDSFRDSLRGFVNSEEIRIFPPEFVRNYLTWVNNLKDWCISRQLWWGHRIPVWHNKHDENVICFDGEGGPEEVMRDPESWYQDPDVLDTWFSSGLWPLTCFGWPDENSLDLKKFYPTAVLVTGHDILFFWVTRMVLMCSAMVDTEPFSDVFLHGLIFGKSYREYDEKGEWFYVSGERKRDYDKGKALPKNVVAKWEKLSKSKGNVIDPIEMIEAYGADAVRLTLCSCANRGEQIDLDYHLFEEYKNFINKLWNGARFIFGHISELTSRDLEEGVNQDLLGLEDFYILDRFNELLDLIDGHYNCYSFDKIASLAYDFFKNDLCSTYLEIIKPTLFGKQDSDQQRATKRKLLATLLINILGVLHPIVPYITETLFQKLKATLGTVENGKGDSVTGHAVSMLRSEACMVAEYPKPIHVAFPQGLRESFGIAERLVYTIRNIRGEMQLDPREPLQAFVISSEKKELVDVCIPIMCALGGVKTVEQLAEAPKDSIFSLGVVEGIQVGVILPPEHLAKERVRLEKEKTRLEKSIDSVSKLLASEDFRTRANPSLVQAKKDSLRNSQRELQSILDKLASL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_HISS2
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGSRAQKTRAEVSGSGKKPWRQKGTGRARSGDIKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFEIDVPKTKVLVQKLKDMALTDALIITASLDENLFLAARNLYKVDVRDVQAIDPVSLIAFDKVVVTVDAVKQIEEMFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GUAD_YEAST
Sequence: MTKSDLLFDKFNDKHGKFLVFFGTFVDTPKLGELRIREKTSVGVLNGIIRFVNRNSLDPVKDCLDHDSSLSPEDVTVVDIIGKDKTRNNSFYFPGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHGTTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVKYIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKDENIHVQTHLSENKEEIQWVQDLFPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECRVRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATMGGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKEKDQMQEQEQEQGQDPYKNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQI
What is the function of this protein?
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
What are the official names of this protein?
Probable guanine deaminase, Guanase, Guanine aminase, Guanine aminohydrolase, GAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_HELPY
Sequence: MDNYTYSELLKSLQNKCDNIALIIKPEKIKQELERIEKEQEDPNFWQDVLKARDTNKEKVRLNRLLETYQKTKNSLDESVELFELAQNDNDEVTLSLLYEEAPILENSVQKVEIEIMLSGENDASNAIITIQPGAGGTESQDWASILYRMYLRWAERRGFKSEILDYQDGEEAGIKGVAFIIKGENAYGYLKNENGVHRLVRISPFDANAKRHTSFASVQISPELDDDIDIEIDEKDVRYDYYRSSGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKASALKMLKSKLYELELEKQQSSAKNEEKSEIGWGHQIRSYVLAPYQQVKDARSNTAYSNVEAILDGDIDAILEGVLIAKA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_MYCAP
Sequence: MERNTRKTLQGKVTSARGDKTIIVEVESHRSHALYSKRYRVAKKFAVHDENNIAKVNDIVTIMETRPLSKTKHFRLVAVKQAAMQGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: FMT_HELMI
Sequence: MRLVFMGTPDFAVPTLEAIVAAGHEVALVVTRPDRPRGRGQKPQPSPVKEAALRLGLPVDHPACLDNEFVQKLKDLGVEAGVVVAFGRILPPRLLDAFPQRWINVHASLLPKYRGAAPIHRAVIDGEKETGITTMLMSEGLDEGDMLLKRSLAIGPDDTTGQVHDALAELGARLLVETLAAMEAGRLQPQPQDGSQASYAPMLARADEQVDWSAPAEAVHNRVRGMNPWPGAFTMDEGKILKILRGRLRHEGLPLPDPTGSAAHPGEILQIVGDEVAVATGAGVYWLSEVRPAGGKTMTAGAYARGRRIGPGFRFG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DDRGK_DROWI
Sequence: MDLILLVGIAVALLVILATLYFLQNKNKAAGEAKPAAAAPRRGVPQRAQEGVPRRAQIARNQRNRLQQNAPAPAPEAVAPAAAGDSDDDEENVGADGARLPQGAVLNEKMGAKKRAKMEAKEQKRLQREHELQEREKRKVKEAKEDAERKQQEEVEAEAERKKLDAERLAKEERERKEHEEYLKMKAAFNVEEEGFEEGDADDQESLLADFIQYIKDNKVVLLEDLAVAFKLKTQQAIERIQELQANGSLTGVIDDRGKFIYISQEELAAVAKFIKQRGRVSIAELAESSNNLINLTPVQSAAGGDS
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins.
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: KCNE4_HUMAN
Sequence: MHFLTIYPNCSSGVVRAQSRTEQKNPLGLDDLGIQNLGQTVSLAPAVEAASMLKMEPLNSTHPGTAASSSPLESRAAGGGSGNGNEYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMKPLPVVSGLRSVQVPLMLNMLQESVAPALSCTLCSMEGDSVSSESSSPDVHLTIQEEGADDELEETSETPLNESSEGSSENIHQNS
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  May associate with KCNQ1/KVLTQ1 and inhibit potassium current.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 4, MinK-related peptide 3, Minimum potassium ion channel-related peptide 3, Potassium channel subunit beta MiRP3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AES_SALPK
Sequence: MKPENKIPVLTRLSDKMKAVVNFQQPGLPPWPADGDIETQRQYYLLERRFWNADAPSMTTRTCAVPTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDTHDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEKIGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHQTLQAHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_MYXVL
Sequence: MAMYGGQIHLIIGPMFAGKSTELIRLVKRYQIARYKCLVVKYEKDARYGNGVRTHDNTCISAVPTASLDDVESISEHVEVIGIDEGQFFPNIVSFCERMANAGKVLIVAALDGTFQRKPFTNICELIPLAENVTKLNAVCMYCYKDASFSKRLGNETEIEIIGGSDKYKSVCRKCYFF
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: RL9_STRA1
Sequence: MKVIFLQDVKGKGKKGEVKEVPTGYAQNFLLKKNLAKEATTQAIGELKGKQKSEEKAQAEILAQAQELKTQLESETTRVQFIEKVGPDGRTFGSITAKKIAEELQKQYGIKIDKRHIDLDHTIRAIGKVEVPVKLHKQVSSQIKLDIKEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RILP_HUMAN
Sequence: MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA
What is the function of this protein?
Rab effector playing a role in late endocytic transport to degradative compartments (PubMed:11696325, PubMed:14668488, PubMed:27113757, PubMed:11179213, PubMed:12944476).  Involved in the regulation of lysosomal morphology and distribution (PubMed:14668488, PubMed:27113757).  Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments (PubMed:11179213, PubMed:11696325).  Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes (PubMed:12944476).
What are the official names of this protein?
Rab-interacting lysosomal protein.
What are the subcellular locations of this protein?
Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle, phagosome membrane. Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
Protein: SPOK4_PODAS
Sequence: MSDKDRITQLLRKLEEAKAREEEAKAREAQERCEKERLQLEHRKTTFLEYLRNCHRHLYNALRLTDTSRSSTGYTKVVGKYYPKRLRPWTNFTNVLHPRYFDLVQKICGQRQLFEPASTTKNLGTIISDHLAGNEKAIDRFEVDAVERPVQGILKVLATHEEAGKAYRCPEFRFSANLRELTQEDDRSSGADDNTSDGSLERRQQAGPNKRPTSKRKYICSNRQPDGVGIRMQPGGGQTQAFIYDYKAAHKVAIEHVRSATAKEHLFHEVVARINDDKLSRDEEVQRREQAEAFIAMALTQVFDYMITYGVSYGYVAAGRCLLLLYVDRDDWQTLYCHPCLPADDVGEPTNDWTDRLSHTAVAQLVSFCLSSFQSEALEGQSLETALSVAKATLKTWSESYADVAYLGLEPPELSSAASSQNTENSEYTSEAKPTGRKVALRSQSSCKPAAVLPQGNEHDEHDEDHSEPGASRSRLAANKRKRGPSSGGEDEDIAMADPEPTRQYCTQACLLGLKRGKDLDENCPNVSLHRFDGSSRHPVNAHRFTDMVKQQLLLSPYKGCRMVDFWDKRGAMGWLFKLELFPYGYTFVGKGTLEDRLSRLEHEGRVYARLDHLQGDVVPVHLGLVRLDRGYILPGLEFVVYMMLMSWAGQTPSASMADAETLKRESLTAIWSEGVDHGDDNRANYLWNAERCRIMIIDFDRAHLFPPLKARAVSRLSKPKRKRETPNSYLTEITGREARYVFKQMDRSPRATPSHGG
What is the function of this protein?
Promotes unequal transmission of alleles from the parental zygote to progeny spores by acting as poison/antidote system, leading to poisoning of progeny that do not inherit the allele (PubMed:31347500).  May possess DNA nuclease activity that leads to spore killing, and a kinase activity that confers resistance to the nuclease activity (By similarity).  Can suppress meiotic drive by the P. comata SPOK1 protein (PubMed:31347500).
What are the official names of this protein?
Meiotic driver SPOK4, Spore killer 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y9882_DICDI
Sequence: MNENNKNNSSEDLNNNNNNNNNNNNIKKTHHRYSAKYKHSLVPSNVGNSGLSGNGVSQKELMSTFKYKSTRTPRLKIEPTIDNLFPSQSTSKSKSNTTNSSPITIMKPKVSKSISNYSNNKYNNNNNNNNNVSTSTSTPIPTTATTTNGNNIDSSLFTSLNSIQTTINGKQSTMIPFSPYSLINCLNSMSSLDENEINNLPIFAPILPPINQQSVNDLNNNNKNDNNKNDNNKNNNNNNNNDNNNNDDNNPTTKKKKVKSQYYMESLAERLSNSNSNGE
What are the official names of this protein?
Putative uncharacterized protein DDB_G0268234.
Protein: RL31_SYNE7
Sequence: MPKADIHPQWYPEAKVYCNGEEVMTVGSTQPELHVDVWSGNHPFYTGTQKIIDTEGRVERFLRKYGMLEGDQAKSEA
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SOMA_CEREL
Sequence: MMAAGPRASLLLAFALLCLPWTQEVGAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity).
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_FUSNN
Sequence: MAAKKDKSVPDSKITDKEGKEKAVKDAMAAITKGFGSGLIMKLGEKSSMNVESIPTGSINLDIALGIGGVPKGRIIEIYGAESSGKTTLALHVIAEAQKQGGTVAFIDAEHALDPVYAKALGVDIDELLISQPDYGEQALEIADTLVRSGAIDLIVIDSVAALVPKAEIDGEMSDQQMGLQARLMSKGLRKLTGNLNKYKTTMIFINQIREKIGVTYGPTTTTTGGKALKFYSSVRMEVKKMGTVKQGDDPIGSEVIVKVTKNKVAPPFKEAAFEILYGKGISKVGEIIDAAVAKDVIVKAGSWFSFRDQSIGQGKEKVRAELEINPELLAQVEKDLKEAIAKGPVDKKKKKSKKEASSDDTDDENLEIDDAIDENND
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.