PharMolix/UniProtQA huggingface dataset:
Protein: NAGB_STRP6
Sequence: MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQEMVKSRLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDVEAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRFFTSIDDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKHDHVIVIVDEAAASQLD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL22_AZOSB
Sequence: METKAILRGVRLSAQKGRLVADLVRGKSVDQALNILAFSPKKGAKIIRKVVESAIANAEHNDGADIDALKVKTIYVEEGTTLKRFTARAKGRGNRILKPTCHVFVTVGE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y756_AQUAE
Sequence: MDKKELVEKIALNTLVFETLGQPEKEREFTIQDLRRWGFDLILGKKNGVRTFFASQAGREVGDKWEEGGATYEIEEILLELPENKKLFAHIETSEGVAYIVAELREGKENLEILRTPAPTLLMAFFKKHRLHELANNLKSVGVITEFYKQRGRESLPLPYKKLPLVARDFLERAKKVEKMAGFGRVALAYFGKTREKDNRFRVSWLLPTIALFDIDISEKANTALEEFK
What are the official names of this protein?
UPF0128 protein aq_756.
What is the protein family that this protein belongs to?
Belongs to the UPF0128 family.
Protein: BETB_BURM7
Sequence: MSVYGLQRLYIAGAHADATSGKTFDTFDPATGELLARVQQASADDVDRAVASAREGQREWAAMTAMQRSRILRRAVELLRERNDALAELEMRDTGKPIAETRAVDIVTGADVIEYYAGLATAIEGLQVPLRPESFVYTRREPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLSALKLAEIYTEAGVPAGVFNVVQGDGSVGALLSAHPGIAKVSFTGGVETGKKVMSLAGASSLKEVTMELGGKSPLIVFDDADLDRAADIAVTANFFSAGQVCTNGTRVFVQQAVKDAFVERVLARVARIRAGKPSDPDTNFGPLASAAQLDKVLGYIDSGKAEGAKLLAGGARLVNDHFASGQYVAPTVFGDCRDDMRIVREEIFGPVMSILSFETEDEAIARANATDYGLAAGVVTENLSRAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGITTLEHYTRIKSVQVELGRYQPVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PEX12_DROME
Sequence: MAEAANVRQNLQNVPSIFEISASETLDNLIYPALSKIFDYFGLRLDFKLWGSLRIQEELSPLLTWLLQYLYLRKRASSFGESFYGLQRTVTTTGDLLNRRQQFASATLLTFMPYVERKLRTRITRHEDTSPWEQRLLSAFHAFHAAKAAHTFFYLVKYASNHSPIFRLLGLTLRYPSEPPKEDQWTYVVLKMLEVLAFFLQFVQWWYSNDQRRKVGGTLINPEAMPRKQLPKEVQQSLPQRGECPVCLLSIQTPTACSVSGYVFCWKCIVSHMKEHGTCPVTHYPISLDDLVRIYET
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:21669930).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity).  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Peroxisome assembly protein 12, Peroxin-12.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: SUCC_SYNFM
Sequence: MKIHEYQAKQLFQKYGVPIPRGKAAFTVEEAKAVGAELGTFPVVVKAQIHAGGRGKGGGVKLAKSAAEVDQYAKGILGMTLVTHQTGPEGRLVKKLLVEEGLPIEKELYLSVLPDRGTSKIVFMASEAGGMDIEEVAAKTPEKIIKVFIDPLLGFKGFHANELAYGLNLKPELIKQFNAMVAALYKLCTDYDCSLVEINPLVLTSDNRVIALDGKINFDDNAMYRHKDIQEYRDLDEEDPFEIEASKFELNYIKMPGGNIGNMVNGAGLAMATMDIIQQAGAAPANFLDVGGGASAEQVENGFRIILADPAVKGVLINIFGGILRCDRLANGVVEAAKKVGIRVPVVIRMEGTNVEQGREILAKSGLNLINAKDVADAAQKIAAVAKG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GPMA_METMA
Sequence: MIITGHLILVRHGEPGLKPGERLSGWIDIPLSRKGIEEALECAKALENIEIDIAFASDLVRTQETLFIILSGQKKTGVVVHEKTEDKVPPEKLDWYSYPEKLGEDLIPVYTTPALNERYYGKLQGRKKQKMEEKYGAEQVANWRWNFEPGPPEGESLKAVYERTVPYFRKKVMPALEGGKNVLICAHQSSLRALVKYIEDISDKDIREVRLSTGELAIYHFSEGKLVRENEELGPELKRNI
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AB1K1_ARATH
Sequence: MESIHCNSLLNPNFSLNQRRRRINHAVLNRRDALLRSLNAVELRRSRTFSAVRTSNFSVTAAATDVGGRNSTDASVMTTAMSGVERGVRVGKSSSALEQLDIERGVCVPFRKYSPETVRSKVLESRGAVVSLVSRGVEIVWTLGLYWSTLTYDFLVGRDEEVVPFRARQLRNLLCNLGPSFIKAGQVLANRPDIIREDYMNELCILQDDVPPFPNEVAFNIIEEELGQPLENIFSKISSQTIAAASLGQVYRATLRATGEDVAIKVQRPQIEPIIYRDLFLFRTLASFLNGFSLQKLGCNAELIVDEFGEKLLEELDYTLEARNIEDFLENFKDDPTVKIPGVYKNLCGPRVLVMEWIDGIRCTDPQAIKDAGIDLNGFLTVGVSAALRQLLEFGLFHGDPHPGNIFAMQDGRIAYVDFGNVAVLSQQNKQILIDAVVHAVNEDYGEMANDFTRLGFLAKDTDVSPIVPALEAIWQNSAGKGLADFNFRSVTGQFNKLVYDFPIRIPERFSLVIRSLLTQEGICFTLKPDFKFLEVAYPYVAKRLLTDPNPALRERLIQVLFKDGVFQWKRLENLLSLAKENVAKMSSNPNLRVKRVESKLDLTDTIKDGARLFLLDEGIRRKLILALTEDSKLHVEELVDVYRLVEDEVDIPTLAMQVVQDLPNVFRDFVLSWSNSVLSDR
What is the function of this protein?
Kinase that can phosphorylate the tocopherol cyclase VTE1, a key enzyme of tocopherol (vitamin E) metabolism and involved in the recycling of oxidated alpha-tocopherol quinone, possibly stabilizing it at plastoglobules.  Regulates also plastoglobule protein composition (PubMed:24267661).  Prevents photodamage of chloroplasts under continuous red light, thus working in opposition to ABC1K3 (PubMed:25882344).  Together with ABC1K1, contributes to plastoglobule (PG) function in prenyl-lipid metabolism, stress response, and thylakoid remodeling (PubMed:23673981, PubMed:24267661).  Involved in chlorophyll degradation and in the maintenance of the number of chlorophyll-binding photosynthetic thylakoid membranes (PubMed:22447966).  Ensures photosynthetic electron transport by regulating the homeostasis of plastoquinone, beta-carotene and xanthophyll lutein, as well as membrane antioxidant tocopherol metabolism (PubMed:24267661).  Seems to affect specifically stability or turnover of D1 protein, product of psbA, one of the four core subunits of the photosystem II (PSII) (PubMed:25882344).  Required for photooxidative stress responses, including the induction of oxidative stress response genes (e. g.  FSD1, CSD1, CAT1, and UTG71C1), to prevent photosystem II core and chlorophyll degradations (PubMed:22447966, PubMed:23673981, PubMed:24267661).
What are the official names of this protein?
Protein ACTIVITY OF BC1 COMPLEX KINASE 1, chloroplastic, ABC1-LIKE KINASE 1, Protein ABC1-LIKE KINASE RELATED TO CHLOROPHYLL DEGRADATION AND OXIDATIVE STRESS 1, AtACDO1, Protein BLEACHING AND DWARF IN RED LIGHT 1, Protein PROTON GRADIENT REGULATION 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule. Plastid, chloroplast.
Protein: AAS_ECO24
Sequence: MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTLD_LEIXX
Sequence: MKAVHFGAGNIGRGFVGLLLHEAGYEVVFADVNAELIEALAAADSYDVRLVGDETVTKTVTGFRALNSATAEDELVGEIATADVVTTAVGPRILRFVAPVIARGLGARASGAPRLVVMACENAIGATDLLAAELMDGLQDGDTRDELAARAVFANTAVDRIVPAQDPASGVDVTVEAFFEWVVDRSPFAGAEPPIPGAHFVDSLGPYIERKLFTVNTGHATTAYTGFLEGAATISEAIAKPSVLATVEAVLEETSAALTAKHGLDPEELAEYRAKILNRFRNPHLVDEVTRVGREPLRKLGRNDRFIGPASDYARYVGGAPSALLAAVGAALRFDLPGDSQSAELQQLLRKTEPGGIVTEVMGVEPGDALYEPLVAVVRTAQG
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: GATB_AROAE
Sequence: MSRNDWEVVIGLEVHAQLNTASKIFSAASTAFGAEPNVQASAVDIALPGVLPVLNGGAVERAIRFGVAIGATVAPKSVFARKNYFYPDLPKGYQISQFELPVVQGGAITIRVGDGDKAYEKTVQLTRAHLEEDAGKSLHEDFHGMSGIDLNRAGTPLLEIVSEPDMRSSAEAVAYARALHALVRWIDICDGNMQEGSFRCDANVSVRRPGGPLGTRREIKNLNSFRFLQQAIDFEVQWQIGTIEDGGRIQQATVLFDPDTGETRMMRSKEDAHDYRYFPDPDLLPLVIPSEWIARVRSEMPELPGAMKARFINDYGLSAYDAASLTAAKEIAAYYQAMLATADTKPGSQVPKLGANWVMGELAAQLNRAERDIGDSPVTPAQLAGLVQRIADGTISNNIARKVFAALWNGEGGSGADAADRIIEAQGLRQVNDSSALEPLIDEVLAANRKSVDEFRAGKEKAFNALVGQVMKASRGKANPAQVNEMLKRKLDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: KTXI_LYCMC
Sequence: CIILLLTIFEINADVKVTDCSKDEYSWCVEKCTKVRSKVRQCKVINDSVKCQCH
What are the official names of this protein?
Putative neurotoxin-I.
What are the subcellular locations of this protein?
Secreted.
Protein: BTUC_SALPA
Sequence: MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLAGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL10_RICM5
Sequence: MLRSEKPVAVEDIVNIYKESPSIIITHYHGLTVSQVSSLRESLKSKEAGFKVVKNTLAKIAANQTGLDSIANLFAGPTAIVYSKEPVEMAKLVVNFAKANDNLKIIGGIVDNHVLDEHSIKELSKLPALNELRGKIVGLLQAPATKVVGVLQAPSSSMARVIQAHASKN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GRG1_NEUCR
Sequence: MDTLKNAANYVGDKVQGATATASKEANKDVAKDSNQGVGTRLNAAGDAISDKVSENKHDAKAEAHKQGATH
What are the official names of this protein?
Glucose-repressible gene protein.
Protein: NCB5R_ASPFU
Sequence: MSALSSENINGVYIPSALLLFGTFIVKKEFVPYAVAVTAILAGLKLFTGGNKPRKVLNPTEFQEFVLKEKIDVSHNVCIYRFALPRPTDILGLPIGQHISLAATIEGQPKEVVRSYTPISSDNEAGYFDLLVKAYPQGNISKYLTTLKIGDTMKVRGPKGAMVYTPNMCRHIGMIAGGTGITPMLQIIKAVIRNRPRNGGNDTTKLDLIFANVNPDDILLKEELDMLAAEDPDFNIYYVLNNPPQGWTGGVGFVTPEMIKEHLPAPASDVKILLCGPPPMISAMKKATESLGYTKARPVSKLEDQVFCF
What is the function of this protein?
NADH-dependent reductase for dph3 and cytochrome b5.  Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1.  By reducing dph3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, Microsomal cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: Y1038_HAEIN
Sequence: MSKAMISRENYLQQLIQFKDTDFIKVISGVRRSGKSVLLMQYRDYLQQQGIASENILYLNFESFEYQWVKDAQDFQQLIQEKMPSSQEKIYFLIDEIQFVEGWQKIVNALRVSFNTDIVITGSNANLLSGELATLLSGRYVEIKIYPLSFKEFLHAKNVDSQSRLVDKLYSEYEKYGGFPSVVMADEPLKETILSGIFDSIVLNDIAHRAGVKDTHILKSVILFLADNVGQLVNPSKISNTLTSERVPTSNHTISKYLDLLENAFLFYKAKQYDIRGKGYLKTNAKYFIVDNGLRRHAIGKKGANYANRLENIVFIELLRRGYSVDVGKLDSKEIDFIARKADEILYVQVAFEIPENTHETDNLLHIKDNYKKILITGKYYEQTEIDGIEVIYVVDWLLQ
What are the official names of this protein?
Uncharacterized protein HI_1038.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1544 and MJ1637.
Protein: ACLY_MOUSE
Sequence: MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWAHLLQDHPWLLSQSLVVKPDQLIKRRGKLGLVGVNLSLDGVKSWLKPRLGHEATVGKAKGFLKNFLIEPFVPHSQAEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNTEDIKRHLLVHAPEDKKEVLASFISGLFNFYEDLYFTYLEINPLVVTKDGVYILDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPEGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRADEVAPAKKAKPAMPQGKSATLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTPGVKMIVVLGEIGGTEEYKICRGIKEGRLTKPVVCWCIGTCATMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVAKGAIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQRRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDFVKQHFPATPLLDYALEVEKITTSKKPNLILNVDGFIGVAFVDMLRNCGSFTREEADEYVDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM
What is the function of this protein?
Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
What are the official names of this protein?
ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, Citrate cleavage enzyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GPX4_MOUSE
Sequence: MSWGRLSRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPQVIEKDLPCYL
What is the function of this protein?
Required for male fertility by stabilizing the condensed chromatin in sperm nuclei (PubMed:12566075).
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Nuclear]: Nucleus.
Protein: OSG1_CAEEL
Sequence: MLNPNDADDSDSSTDSSPPVAVPRPKRSATVSPSTRNSFYNSRRRSDANLNFFNERERQRERRRSMVRASRERSESRRASQQNLRKTNSEPNVDMPSIDVEALQKLLLSIPKFVSASRNRINQRHDSDSGGEMTTEIEELKDAAKSIQSLQRVLAYPSQTSSDRGGNRRLADPVESCLESSVFSDVDESSLATDTIEGRRSGISTRLGHPRGVMQFIPSIRNDQFVPTSEIRRNSISRKSSVPDGFMTSEMESEPVPNVRNRRRGIVDEMFSSSTSLLVDRPSETLAGVNRFAKLLDTFRSRPTSPEQHPSISWNPYVYSDGGEALETCGMEDSLHEADILLWKKRSRASLRRHYSVRHLAARELLDTEKSFVEGLEFLVTKYMRPLRQPLECTLIEASLVDKIFYRIPEILAHHQVLLTTLSQRIDQWHKDAILGDVLLAHFSKQSMIETYISFVDNFKFAKASIIQARQKHAFEKYYNRCCRDHPNKLDLDSLLISPIQRVPRYELIVKQMLKHTPVEHEDRERLLRAQRHIHCLAVAINQHKDGSEQMEQRLREIEAIVDGLDDLVTKDRTLLRHDIITLKGTDRERCIFMLSDLLLVTSVKKKPKVLYSKMSSQSMGFLEGNRFKLLFKVALEDVQISKDTLSQLEEVERKLESSREDDRVLKKMSQLCSLLKCERKVLMEMLETMETSNSMSIRELNEQMSSDPDLSAVHLDVLTSNGFEPFVLEFPNAEKRSVFEAMFKDAKATLAKNLLAAPSCSLKTIIAHQTRPGLQLCTATVVPGKRVDSTPSLWVCASDKFSGQVAVMALDTGEITIESCSAIGNAAVTAMCTVPPPMKLRKRKIKSQKSLEHLLNETIMDINSSGSDTESSSDEGTSTAGQTTVWIGNDDGEVFVVNSTERVRSRARDRLARLRNSITSICAANGNVLVATSYSNQVQLLLFRPASDGSWDLENPQTVGHVCQAPITSMQLIGRRVIIASGNWLHAYFVDTGKFQPPVEILPSSDVITLMYVTGQNVFLCGRKSTEVFVVDVFNLSIINHFNVVSFVRSQLSGREHILREHKMGCLRISCLTVARSHLWIGTSAGCVLSTSVQSARSQPTPDLRVCEIGHSGPCRILLPVHTPSHSNHPSRKQKRSSLNVPAQQSSQLMLVSCGEGLDDGTATQDPSTDAINHLIFWKCS
What is the function of this protein?
Probable guanine nucleotide exchange factor which regulates the Rho GTPase rho-1.  Functions in ASE sensory neurons where it promotes neuronal degeneration under conditions of oxidative stress.
What are the official names of this protein?
Rho guanine nucleotide exchange factor osg-1, Oxidative stress-susceptible GEF1.
Protein: RUXX_METTH
Sequence: MIDVSSQRVNVQRPLDALGNSLNSPVIIKLKGDREFRGVLKSFDLHMNLVLNDAEELEDGEVTRRLGTVLIRGDNIVYISP
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: FGF13_PONAB
Sequence: MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
What is the function of this protein?
Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity).  Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity).  Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity).  Regulates voltage-gated sodium channels transport and function (By similarity).  May also play a role in MAPK signaling (By similarity).  Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity).
What are the official names of this protein?
Fibroblast growth factor 13, FGF-13.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Cell membrane, sarcolemma. Cytoplasm. Nucleus. Note=Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes.
Protein: SFSA_SALAR
Sequence: MLFSPPLQRATLIQRYKRFLADVITLDGTALTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQSGVFICVNTLWANRLTKEAIQEDRLPELAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVLFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSATKMELNKSVPIML
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: TI10C_ORYSJ
Sequence: MAGRATATATAAGKDRSSFAVTCSLLSQFLKEKKGGGGGLQGLGLGLRPAPAAPPAAGAGGAFRPPPTTMNLLSGLDAPAVEVEPNTAETAADELPLIKAPADQQSDESASEAAGEKAQQLTIFYGGKVVVFENFPSTKVKDLLQIVSTGDGVDKNTGTAATQSLPRPAHNSLPDLPIARRNSLHRFLEKRKGRMNANAPYQANCTAAPSKQANGDKSWLGFGQEMTIKQEI
What is the function of this protein?
Repressor of jasmonate (JA) responses.  Acts as a repressor of JA-induced resistance to the bacterial blight pathogen Xanthomonas oryzae pv.  oryzae (Xoo) (PubMed:23104764).  Regulates JA-induced accumulation of linalool at the transcriptional level of linalool synthase gene LIS.  Linalool is important for resistance to bacterial blight pathogen Xoo (PubMed:23889289).
What are the official names of this protein?
Protein TIFY 10c, OsTIFY10c, Jasmonate ZIM domain-containing protein 8, OsJAZ8, OsJAZ7.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Mainly localized in the nucleus.
Protein: RL28_GEODF
Sequence: MSKVCEICGKGPSFGNNVSHANNKTSRTWYPNLQKIKAVKNGTVRSIKVCTRCIRSGHVTKAL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CP21A_ARATH
Sequence: MRREISFLLQPRCLLLLVALTIFLVFALFNTGKDEEKQVIEDHEITNRVFLDVDIDGQRLGRIVIGLYGTVVPKTVENFRALCTGEKGKTSSGKPLHYKGTPFHRIISGFVIQGGDIIHGDGKSSDSIYGGTFPDENFKIQHSHAGMVAMANTGPDSNGSQFFITTVKASWLEGEHVVLGKVIQGMDNVFAIEGGAGTYSGKPRKKVVIADSGEIPKDKWDEER
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP21-1, PPIase CYP21-1, Cyclophilin of 21 kDa 1, Cyclophilin-21-1.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.