PharMolix/UniProtQA huggingface dataset:
Protein: RM24_YEAST
Sequence: MQKIFRPFQLTRGFTSSVKNFRQWRLIETRKIAKQPNYQVGDAKPLHMPKERKKFPDYKYGESNIFKQSNKGLYGGSFVQFGNNISESKAKTRKKWLPNVVKKGLWSETLNRKISIKMTAKVLKTISKEGGIDNYLTKEKSARIKELGPTGWKLRYRVLKRKDEIENPPHKDAPIIEMAGGKKAKIYYDEIVNGSPRKISVGRRRLMSFLYPLEKLEYRSVGKDLNYKKFVELFADVPVKDILARLEDHKFDLSTITV
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L24, mitochondrial, Mitochondrial large ribosomal subunit protein bL28m, YmL14/YmL24.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: ATPF_LOTJA
Sequence: MKNITDPFPCLGYWPSAGSFGFNTDILATNPINLSIVIGVLIFFGKGVLSDLLDNRKQRILRTIRNSEELREGAIEQLEKAQARLKKVETEADRFRVNGYSEIEREKLNLINSIYTTLEQLENYKNETIHFEQQRAINQVRQRVLQQALQGALGTLNSCLNNELHFRTIAANIGMFGAMKEKNN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CPR6_CAEEL
Sequence: MKTLLFLSCIVVAAYCACNDNLESVLDKYRNREIDSEAAELDGDDLIDYVNENQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLDLDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCCKSCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPHDLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKLNSLTSRLHRHHRRHVYDDNY
What are the official names of this protein?
Cathepsin B-like cysteine proteinase 6, Cysteine protease-related 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: RL19_CERS1
Sequence: MNLIAQLEAEQIAALGKTIPDFKAGDTVRVGYKVTEGTRSRVQNYEGVVIGRKGGNTISASFTVRKISFGEGVERVFPLYSTNIDSIEVVRRGRVRRAKLYYLRSRRGKSARIAEVTNYKEKSE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SYDND_BEUC1
Sequence: MLRTSPAGSLRAEHTAQVVTLTGWVDRRRDHGGVAFIDLRDASGIAQVVIRDEAVAHPLRNEFVLQVTGEVSRRPAGNENPNLPTGEIEVVASDVVVLNSAAALPFQVSTALADTEAIGEEVRLKYRYLDLRRPAPARAIRLRAKANQAARRVLDAEEFVEIETPTLTRSTPEGARDFLVPARLAPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDVEMSFVEQDDVIALAEKVLVALWELIGFTIPTPIPRMTFDDAMRLYGTDKPDLRFGNPIVELTSYFADTPFRVFQSEYVGAVVMAGGASLPRRQFDAWQEWAKQRGARGLAYVTFPEDGSDLGGPVAKNLSDAERAGLREATGAAPGDAVFFAAGATTPSRALLGAARQEIAKRTGLIDSADQEGAWAFVWVVDAPLFKPTGDAADDGDVALGHSAWTAVHHAFTSPTPEWIDTFEQDPGSALSNAYDIVCNGNEIGGGSIRIHRRDVQERVFQVMGIDAAEAQEKFGFLLDAFSYGAPPHGGIAFGWDRILALLTGSESIREVIAFPKSGGGYDPLTQAPAPITAEQRRESGVDAVPDDETAPQA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y013_YERPY
Sequence: MSAIALTVSMLALVAVLGLWIGNWKIYGVGLGIGGVLFGGIIVGHFAQTYQIVLNGDMLHFIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNCFAILMVVVGGLVTAIIHKLFAVPLPIILGVFSGAVTNTPALGAAQQILTDLGSPPQLVSQMGMGYAMAYPFGICGILLVMWLIRLFFKINIDREAKAFDSSYGQNRELLQTMNVAVRNPNLHGLSVQDVPLLNSDEVVCSRLKRGDLLMVPMPATVIEIGDYLHLVGQRDALEKVRLVVGEEVDVTLSTAGTALQTARVVVTNEAVLGKKIRDLNLKQKYDVVITRLNRAGIELVASNSANLQFGDILNLVGRPEAIEAVSAIVGNAQQKLQQVQMLPVFIGVGLGVLLGSIPLFVPGFPAALRLGLAGGPLVVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFINTLVNGDGLAWIGYGAMITGIPLLTVGILARMLVKMNYLTLCGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQILAVLFWTL
What are the official names of this protein?
Putative transport protein YPK_0013.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3413_BACC0
Sequence: MSASNLNEISKQILKEEETLQFSSFTNEDALQLGLFIVETAKQEGKVIAVDITKNGVQLFHFKMTGTNEENTKWIERKKRVVSLHDRSSYYMQIQSEITGISYNEKYLLNTSEYAAFGGCFPIRIKDVGVIGMITVSGLPPEKDHELVIRAVKNHLNQ
What are the official names of this protein?
UPF0303 protein BCAH820_3413.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: ULP2_CAEEL
Sequence: MSDSTQMEANAAINEIKKRTRKLDQSLQMRFCADQFFIGNHCTKLASGKSIIISQNSKNRICLRFFMAADPLVGYTGRDFGIAFNQIDHISLKDEQQENPAVLICTLNLSSYTKMCKLQTGLKDVVEKPFLYNKSLARNLTFILKPWNDDPDTFVKISYNDEHREYVHSYDYDVAKSLMFKEVQAVWEQSLKEQLQRRHQTGRVYLTSQLSEMTPREWVQFLADQKLSKIVCHNGSIQYARVEDNPHGRKHTAVATNGFDHRGTRVLNSFGKAHASLATQEKSYAKKRKLTEQSLKLIYRNDRSVWLEGSCAKNLKMPKINSEPNMGEFMGWPDMDNAMTHPTSNFENEDVMKSTKQPNDFVSFEQLQAPPPVLQRQNGAIYSTQSVAFTHISGNDGVEDLTEKISHLGEEAYNIDMANALHAFSDNWHYEIHPNTVHNASFEQLHIGDGNSSIGTIGFNPLEPYPQSSFPQSNNWQQAHGDFTFPQVSFPNTQQGSCLPSTPTAALPPTRPVVEKIPPDTQLFTFPPSGSCTTGMDPVVLLVKDIKTLDRKEFLNDSVMAFMLNYIAFMLSSELMKSVHMCNTFLFVNLTRLLPPLCFSKRRPIEPEHIKIVKDNCPRVLRWTRKFDVLAKDYIIIPINEDLHWLVIAVINPSGAIVDMSNEEASRAAPKCYIVFFDPLSGLDPSKKNHMCHCIKIYLAQLYENTKAPGMKFASKNPTIYDEERVVVTRAENTPIQDNFYDCGLYVLHFIEGLFCYPNRPVNVNDFPNFDWSKFFPEANKMCDLMRDKVYNLILQQADKPARSRLAKFERENKCGLSREGALRKARRHSAVNERRTKRHRDYYARHYSLSPPHRNVMNDDPTFMNPRGLAEMPITRLVRRLRIPEDNFPIAY
What is the function of this protein?
Protease that catalyzes two essential functions in the smo-1 pathway: processing of full-length smo-1 to their mature forms and deconjugation of smo-1 from targeted proteins (By similarity).  May deconjugate smo-1 from the cadherin protein hmr-1 and plays a role in its recruitment to and the maintenance of adherens junctions (PubMed:26412237).  Required for epidermal morphogenesis during embryonic development (PubMed:26412237).
What are the official names of this protein?
Ubiquitin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: TCTP_CRYNB
Sequence: MLIYQDVLTGDEMISDAFPIKEIGDIAYEVDCANIIIKEGDVDIGGNPSAEEAAEALEEGAQQVNNVVHSFRLQSTSFDKKSYLTYLKGYMKAIKSKLQESNPDRVAAFEKGAQDFAKKIVANFKDYEFYIGESMNPDGMVCLLNYREDGVTPYFTMWKDGLKEIKI
What is the function of this protein?
Involved in protein synthesis.  Involved in microtubule stabilization (By similarity).
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIS4_PROM4
Sequence: MELIPAIDLLEGNCVRLVQGNYNKVTKFNSDPVSQALRWEDMGASRLHIVDLDAARQGFSSNDDVIKQIAKSLSIPIQIGGGIRTSKRAKELLDYGIDRVIIGTAALEDPRLVEDLASAFPKKIVLGIDAKEGKVATRGWIEQSDVRTEDLIKQFSNAKIAAIISTDISTDGTLEGPNLKSLTSVAKVSNAPVIASGGIGSLADLISLTTLEKAGVTGVIVGRALYDNKFSLEEAIKVLLNIDLQDQPFNAKNIA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBID_MYCTU
Sequence: MSGTPDDGDIGLIIAVKRLAAAKTRLAPVFSAQTRENVVLAMLVDTLTAAAGVGSLRSITVITPDEAAAAAAAGLGADVLADPTPEDDPDPLNTAITAAERVVAEGASNIVVLQGDLPALQTQELAEAISAARHHRRSFVADRLGTGTAVLCAFGTALHPRFGPDSSARHRRSGAVELTGAWPGLRCDVDTPADLTAARQLGVGPATARAVAHR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: RIMO_STRM5
Sequence: MSQLNPKVGFVSLGCPKALVDSERILTQLRSEGYDIVPSYDSADVVVVNTCGFIDSAVTESLDAIGEAMNQNGKVIVTGCLGKRPEQIREAYPNVLAVSGPQDYQSVMEAVHEALPPKHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHKCSFCIIPSMRGKLVSRPVDEVLREAERLVRGGVRELLVVSQDTSAYGVDVKYAEKMWRDKAYQTRLKALCEGLSELDAWVRMHYVYPYPHVDEVVPLMAENRILPYLDIPFQHASPRILRLMKRPGAVEKTLERVQNWRRIAPDITVRSTFIVGFPGETEAEFEELLSFLDEAQLDRVGAFAYSPVEGATANDLPDAVPEEVKQERLARFMEKQAQISAARLEAKIGTVQQCLVDAIEGDIAVARSKADAPEIDGLVHIQNADQVALRVGEFVDVEITESDDHDLYGDALPAAARPALDLKVL
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_BRUAB
Sequence: MTKTVFVLNGPNLNLLGKREPGIYGVATLDDIEASCKREAGQLELQIDFRQSNHEGDLVSWIQEAGEKNAYVLINPAAYSHTSVAIHDAIRSARVTVVEVHLSNIHAREAFRHHSHVSAVAKGVICGFGAEGYLLGLRALAAIAKEEEKNGQSIKGA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PAQR4_HUMAN
Sequence: MAFLAGPRLLDWASSPPHLQFNKFVLTGYRPASSGSGCLRSLFYLHNELGNIYTHGLALLGFLVLVPMTMPWGQLGKDGWLGGTHCVACLAPPAGSVLYHLFMCHQGGSAVYARLLALDMCGVCLVNTLGALPIIHCTLACRPWLRPAALVGYTVLSGVAGWRALTAPSTSARLRAFGWQAAARLLVFGARGVGLGSGAPGSLPCYLRMDALALLGGLVNVARLPERWGPGRFDYWGNSHQIMHLLSVGSILQLHAGVVPDLLWAAHHACPRD
What are the official names of this protein?
Progestin and adipoQ receptor family member 4, Progestin and adipoQ receptor family member IV.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLSY_WOLPM
Sequence: MEKYVVLILSYILGSIPFSLIITRIKGINLREVGSGNIGATNVARTGNKFLAALALFLDSFKGFIAVYIAQQFCDNNDFYIYVSAILAVLGHMFPIWLKFSGGKGVATTLGILIAFNIDITLVFVIIWIIVFLAFRYSSLASLSATSTAVAWSFFFQRNLFLTLLIIGALVFLKHHRNIVNLLQGKEYKFYR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBSD_PSESM
Sequence: MKKTPLLNIALSRVIASLGHGDILMIVDAGMPVPPGVELIDLALTRGVPDFVSVLDVVLSEMQVESHVLAREMADIKPPALQIIESLNLDDQLGQQRWISHEDLKALSRTAKAIIRTGECQPYSNLALVSGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEH_SULAC
Sequence: MMGVVSLPRVIGKQVYGSLYECDTTVLGEQKVLEQIVRKAAEEGNMTLLDVKAWKIGDGVSIVAIVLESHITIHTWPEYNFATVDVYSCGSHTDPRKAFLYIVKELKARRYTMNEADRSSEF
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: URAD_AMICA
Sequence: MDMRQVNSLSYEEFVETFGNVVERCPVVAAAVWSGRPFANSHDLEASIGEFIDSLPVAGQEGIVRCHPDLAGRDLKRGALTAESRGEQTQAGLTLLDAGDAARMNRLNAQYKERFGFPFVICARMNNKEEILLRLAERLGNEPAQERQCAIEEVKKICQLRLQDIIQCPATHTKL
What is the function of this protein?
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
What are the official names of this protein?
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, OHCU decarboxylase, Parahox neighbor, Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the OHCU decarboxylase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PLXB_DROME
Sequence: MLRKELYCANIIHVLHVLCIIIILGSQHYCVNCIEELPAQALSPLNDIVAQFNLPSIPVQSTASSYGNRSIGNNIESVRDSQSKNYFTHMSFDFMHNVLFAGATNKILKLNENLRVLAEAVTGPLHDSPQCHAGGCPEDIETSLVNNFNKILVVSYAHDGILIACGSIRQGACEIYSLPRFPATPQFFAVPLAANDENASTYAFVGPARYAWKEEDILYVGTTFTNVGDYRHDVPAISSRRLDDLNYAEFSIQQSIINIDVKYRDHFLVDYIYGFNSSEYAYFIIVQKKSHLADEAGYVTRLARICITDPNYDSYTEITVQCTATENNVDYNIVRDAKVTPASHKLAQKMGIKKDDHVLVTVFSPSREISNQPESKSAMCIYSIKDIEDMFIENIHLCFNGTTKDRNLGYISGTINDGRCPIVGSLGNIYNFCSVGLKISGVSPITAHALFHFDNVSVTSVTATSTTDQQHSLAFLGTNMGVIKKVLLSGQSPGEYEEIVVDAGNRILPNTMMSPKKDFLYVLSQRKITKLRIEHCSVYTNCSACLESRDPFCGWCSLEKRCTVRSTCQRDTSASRWLSLGSGQQCIEFESIIPEKIPISELSHLHLIIRTLPEPFNAKYRCVFGNSTPIDAEILENGLGCATPPLDERPLIPTNTDHILVPLSVRSSETNKDFVSRNFAFFDCSHHGNCQECLQSSWGCNWCIFDNKCVHKSLQCRNIENAVSTVGHCPHLKKNRPEILLPVRVPIEIRLEIENLPKPKSAHAGFLCTIHIEAAQMLLPAHVESNKIVVCEKTPYFYEINTHEYQAKVVVTWNFQHYVDTAIVTLYKCDVLGSHREHPDCSLCVTRDPKYKCAWCSNSCVYNETCIADKNSISSGSKSAIENECPLPRIDIIKPLSGPVEGGTLITIEGSNLGIREEDVRGKIFIGSVPCELENYQISVKIECRTGASLYEMSAPIKVANDAGFTESSVQFHFKNVLLTGLYPTIGPRSGGTQLSLIGKFLNIGSTMRAFLDEYECHIDVTQASSSQVSCTTSEATQPEPIRSLHLVIDGANRTLECQISTPSITNTNPTRSNFGSYQLRSLPRQPCSIFNYTQDPRIMQIKPLRSFKSGGRVLTVHGIYLNSIQKPELEVFYDNERVNKTSCVVINSNQMECPSPPVNYKFETFKKTNRKMDTELHLQNSSFQTETRYKNEYDRKKRRADFGDTFRLYTNAGSSANYFVNNNMDVTTFVKVHETQLNLQLSFVMDNVQLVRNLNKYFHDIRSTIVYLADPKYLPFPNDGVKLYKGDSLVIEGELLNLAADEYDVNVTIGTSQCNITSLALNQLLCIPPEQQPLPTDENGVDQSTDLPLVVVKVGRNLRFVIGYLKYDLNKPYVFSHALLVGILTVALLVVVFVIVLIIFRRKSTQAEREYKRIQIQMITLESNVRSECKQAFAELQTDMTDLTADLESTGIPTLDHVNYIMKVFFPGVSDHPILNSPKFREGSPQTNYDAAMVQFEQLIGNKYFLLMFIETLEAQRSSFSIRDRVNVASLIMVVLMNKMEYATEILKSLLLRLIDKSLASKHPQLMLRRTESVVEKMLTNYLAICMYDYLKEYAGSNLFLLFKAIKHQIEKGLVDAITNDARYSLSEERLLHEQVTHSVVILHILQDDLDEKVQCRVNDWDTISQVKLKILDAIFKNTPFSMRPSVNEVDLEWRHGRGGHLTLQDEDLTTKTVNGWKRLNTLAHYGVKESAVMSLIARQNDNYHIPYSKNQNSAPYHNFYFINNSQSHIIINNDIESGLQQPRVYHLVKPNIPDHYMNIKNSVLSGGSPAFQSHVVNNCNDRVNKTIPEVYLTRLLATKGTIQKFVDDFFSIILTVNEELPPAVKWLFDLLDEAARRHDIADTDIVHAWKSNCLPLRFWVNFIKNPDFIFDVNKTYSVDSCLSVIAQTFMDACSTSEHRLGKDSPSNKLLFAKDIPNYRIMVKEFYRDVSRLPQISDQEMSTAMQQLSVRQNEEFDTISALKELYIYITKYKDQIMESLETDINCRKMHLSRKLGNVAATLDGDCTSNC
What is the function of this protein?
Transmembrane receptor that binds the molecular guidance cue Sema2a, to regulate axon guidance and possibly salivary gland positioning in embryos (PubMed:11604137, PubMed:16672342).  Acts as a receptor for Sema2a and seems to transduce signal by suppressing Rac activity and enhancing Rho activity (PubMed:11604137, PubMed:16672342).  As transmembrane receptor for Sema2a, involved in peripheral and central nervous system axon guidance (PubMed:11604137, PubMed:16672342, PubMed:27618755).  During embryogenesis, plays an important role in correct salivary gland positioning (PubMed:27618755).
What are the official names of this protein?
Plexin-B.
What is the protein family that this protein belongs to?
Belongs to the plexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NRDR_METCA
Sequence: MRCPFCGAQDTRVVDSRLSHEGDQVRRRRECGECKERFTTYEAAELNMPRVVKSDGSRQPFREEKLRAGMLRALEKRPVSSDRVEAAITRIEKRLLATGEREVQSRLVGEYVMNELSQLDDVAYVRFASVYRRFEDVNQFREVIDRLESEPDSETAGRQADAFDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ISPF_CUPPJ
Sequence: MMPFDIRVGQGYDVHALVPGRKLILGGVHIPHDRGLLGHSDADALLHAITDALFGAAGLGDIGRHFPDTDAQFAGADSRVLLREAARRVREAGYEIGNVDASVIAQQPKLAPHIPGMVANIADDLGLPATRCNVKAKTNEKLGFEGRQEGIVAQAAVLIWRGAIADAQD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: NASP1_CAEEL
Sequence: MDTENIADASDIRVKDASGDSDEKGNGTTTEEETVEQKEKRLAELLAAGRRALKVNDIDKASDSLSEATELSSEIYGENHENTFDSLYYYGMATLELAKEESQLLKGPGEKESGDEEQAGNSDDKTDEENGETEKEDGEESGEEEDDDDDTMKLSWEILETARCIAAAKIEALEAEQSGISAIEEWNLKLADVLVLLGEHGISDGKYTQAFEDLDRALNIQRNVLPPSSRKIAQTYILIGNACASDANYDETVQYFGKTKDVLIARQTELKHELERGVDDKEKKSEFENELKELEEMMPGVEEMIADAVHSAAQVEETKKAIKAQFEGFTQVLAKLPQEAGDQKEANDISSLVRRPAKRAVDAPTDNQAVKKEKEEEGTTSI
What is the function of this protein?
Promotes normal hermaphrodite (XX) development, in concert with zinc finger protein tra-4 and histone deacetylase hda-1, perhaps as components of a complex (PubMed:17011494).  May act redundantly with nasp-2 (PubMed:17011494).  Involved in innate immune response to B. thuringiensis strain DB27 and S. aureus bacteria (PubMed:23918784).  May play a role in the uptake or spreading of dsRNA (PubMed:23918784).
What are the official names of this protein?
Protein NASP homolog 1.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COBS_DESVH
Sequence: MPTFLHHALLACGFLTRLVPARVATADDMAAAVRWFPLAGLVVGGACWLPFALGLAASHPAIQAWLYVLINLWVTRGLHWDGVADLADAWGSSATGERFWDILKDSRIGAFGVMGLLLGFGGQYIGAHEIFISGRLGVLIAAPIVGRGACVILAALVPPGSRSTLGRLTCAGADRIAIGVAATCGMLALLLTTPAITTVTTIAICGAIVTALAHLARREDGINGDFMGACIAGCEGTVLLAASMG
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGLRD_NEOFI
Sequence: MKRGALLVPFVPLALACVDPGDSNHSCASVFSVSSAAAASFCATFTVSAVTETTGVPAALLSNCDYKTKHLSSACSCLGPATAAAPTQTSAVTPTVAPTTLKANAVAPTTEAPAPTKSSTFAGNGGTTCTVTEYAAISSAVASCSNILLSDVYAPPSSTIDLQNLQTGAAVIFAGTTTFGDTPDDDFDPIVISGTDVTITGADGHVIDGNGAAYWDGKGSNGGSSKPDHFIVAKHMYYSRIENLNIQNWPVHCFDIEHTENLIISGITLDNSAGDAPNSASGSKPAAHNSDGFDIKSSTNLTLQNSWVHNQDDCVAVSSGTDIVVDNMYCYGGHGLSIGSIGGKSDNTVDGVTFSNSQVINSSNGCRIKSNSGTTGEVSNIRYENITVSGITDYGIDIQQDYLNGGPTGKPTNGVKIENITFVDVTGTMSDGKDYYILCGDGSCSNFVFENVGITGGSGDSCNYPTDTCLEA
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase D, PGD, Pectinase D, Polygalacturonase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_YERPG
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLEFSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ENTP2_RAT
Sequence: MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL
What is the function of this protein?
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.  Hydrolyzes ADP only to a marginal extent.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 2, NTPDase 2, CD39 antigen-like 1, Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, Ecto-ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Multi- pass membrane protein.