PharMolix/UniProtQA huggingface dataset:
Protein: ATG9_ASPCL
Sequence: MMTSNILSRFLPPNNSPSVYEAIRQNDADSDSSDVEERAGLTLEDGHGGHYTDHELQDAMVDADQSELPSPDDAFLARESHHRVPSEGPSKSTSRRRKNSRPRWMQAASPGQDFEYGDDDDVPASLLVEGHHDDEDLKSRLPPPPRPLSPHEIQPSLPGPSSQGDQARWRAARDQQPLHNASRRRPPGVKWSLGQPNLNTVDPKEKAMWMWANVDNLDNFLKEVYSYFLGNGIWSILLTRVLSLLTFAFVVGFSTFLTNCVNYHKVRGSKTLDDILVDRCTTKMSLSSTFLLWLLTFFWIGKAFQCLLGIRRLKHMHDFYHYLLGVSDTDIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALVNKDILDLTLPIPFLRNRPLFSQTLEWNLNLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGFMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASVVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGMVPEETNVFDPEYALLEVINYTHYFPSQWKGRLHSDEVRREFAELYQMKIVIFLEEILSMIFTPFILWFSLPRCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVITQGDRREPARQDLRADYFATKDGKMLASYYGFLDNYGANPRGAHPSTKRQFHPPPAFPTLGSPSAMDLGHLGDRADPPQARPFAGQQSTFGPSRFGPTGLADHGSPAPSMLLDPHHQPSASGFRTAHRTAFSRYRSSRAAPPISGAILDDDESPSAPNRNGSARSAAGAPAPPGGSSGGGVGASDSNLEDSWRMNLTGDTDDEDAGAGGENADAIAGGAGVLGLIQQFQRVNQDGRGRTAVGL
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HEM3_HAHCH
Sequence: MPKQHLVIATRQSALALWQAEHVKQRLEALHPGLTVELLGLTTKGDIILDTPLAKVGGKGLFVKELETAMLEGRADIAVHSMKDVPMEFPPGLGLGAILERETPMDAFVSNQYASLDELPEGAVVGTSSLRRQCQLSERRPDLKILSLRGNVNTRLAKLDAGDFDAIILAASGLKRLGFSGRIREELTPEVSLPAVGQGALGIECRLDDPEAMALIAQLQDAETTARVSAERAMNHRLQGGCQVPIAGYAEITGDQMRLRGLVGSPDGAQVLRDEVEGPVAAAEALGTELAERLLQQGAGKILEAVYGNHS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MUTS_SALA4
Sequence: MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATRRNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQDTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPVQALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLDRLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWTLNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FLGC_RHIME
Sequence: MDPLTSALKVSASGLQAESTRLRIVSENIANARSTGDAPGADPFRRKTISFAAEVDRASGASLVEVERLGTDDSDFNIEFDPGNPAADEKGMVKLPNVNILIEMADMREANRAYEANLQTIKQSRDLISQTIDLLRASQ
What are the official names of this protein?
Flagellar basal-body rod protein FlgC.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: FETP_NEIM0
Sequence: MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWAAWTRHQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RPOB_PSEP1
Sequence: MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGASKDHFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYSTEEVLNTFYTTNVFHISGEKLSLELVPQRLRGEVAVMDIHDETGKVIVEQGRRITARHINQLEKAGVKQLDVPMEYVLGRTTAKAIVHPATGEILAECNTEMTTELLIKVAKAQVVRIETLYTNDIDCGPFISDTLKIDTTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSAERYDLSAVGRMKFNRRIGRTEIEGSGVLSKEDIVEVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGVVSDDIVFLSAIEEADHVIAQASAAMNDKKQLIDELVAVRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDKVQRGDIMADGPSTDMGELALGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDSRALAIEKMQLDEIRKDLNEEFRIVEGATFERLRSALNGQVVDGGAGLKKGTVITDEVLDGLEHGQWFKLRMAEDALNEQLEKAQQYIVDRRRLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGVPSRMNVGQILETHLGLAAKGLGEKIDRMLEEQRKAAELRVFLTEVYNEIGGRQENLDEFTDEEILALANNLKKGVPMATPVFDGAKEREIKAMLKLADLPESGQMVLFDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DCAF5_MOUSE
Sequence: MKRRAGLGGSMRSVVGFLSQRGLHGDPLLTQDFQRRRLRGCRNLYKKDLLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETLDVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIRESPHGEPFCLANYPSAFHSVMFNPVEPRLLATANSKEGVGLWDIRKPQSSLLRYGGNLSLQSAMSVRFNSNGTQLLALRRRLPPVLYDIHSRLPVFQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWKIPADPEAGGIGRVVNGAFMVLKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSPYKQPGCTGDLDGRIEDDSRCLYTHEEYISLVLNSGSGLSHDYANQSVQEDPRMMAFFDSLVRREIEGWSSDSDSDLSESTILQLHAGVSERSGYTDSESSASLPRSPPPTVDESADNAFHLGPLRVTTTNAVASTPATPTCEDASSRQQRLSALRRYQDKRLLALSNESDSEENVCEAELDTDLFPRPRSPSPEDGSSSPSSSTSSEDEEELNQRRATTRQRNAMRRRQKTARDERPTGPAKSTNTYIGEDNYDYPQIKVDDLSPSPDSSPERSASTLDVQPSRAPPAANMESVERKIYKAYKWLRCSYISYSNNKDGETSLMAEEADEGRAGTSHKDNPTPSSSKEACLTATAQRDQDLPSEGCSSDACKEGTSAGNPNSGAGHEHSSHPWAEVPEGTSQDTNNSGPLEHSFETKKLNGKALSKALSSRAEEPPASPGPKASGSTLNSASGNCPRTQSDDSEERSLDTVCANHNNGRLHPRPLHPHNNGQSSGELETVACSSPGHLDTDHDSPSLTGTFLHKDCCGSEMACETPSAGMREDPPDPSGLDSSKVVHGQSGLKRHRIELEDTESENSSSEKKLKT
What is the function of this protein?
Is a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex (CRL4), involved in the ubiquitination of a set of methylated non-histone proteins, including SOX2 (PubMed:30442713).  The complex CRL4-DCAF5 is also involved in the ubiquitination of methylated DNMT1 and E2F1 (By similarity).
What are the official names of this protein?
DDB1- and CUL4-associated factor 5, WD repeat-containing protein 22.
Protein: RAB4B_MOUSE
Sequence: MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:14697203).  Protein transport (By similarity).  Probably involved in vesicular traffic (By similarity).  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (PubMed:14697203).
What are the official names of this protein?
Ras-related protein Rab-4B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PYRC_PSEA7
Sequence: MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSAEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNVFAALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREQWQAPASLPFGDFDVVPLRAGETLRWKLLEAEA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: DCDB_PERMH
Sequence: MILNDRKIRELIESKELLIDPLDAVQIQPSSVDLRLGNDFLIYPEDIEILDVRNPDLHNQLKKVVADDEGFIIQPKQFILATTREYIKLPDYLTAFVEGRSSLGRLGLFIENAGWVDAGFEGNITLEFYNANSRPLKIYPGMRICQLVFAKMEEPAENPYRGKYQGQRGTTASRIFLDKD
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RLA5_SCHPO
Sequence: MSASELATSYAALILADEGIEITSDKLLSLTKAGNVEVEPIWATIFAKALEGKDLKELLLNIGSAGAASAPTAAGAGAAAPAEAAEEEKKEEAKEEEESDEDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1-alpha 5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: LLDD_SALDC
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPAALAPMSKGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECA1_BACHK
Sequence: MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDANEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAFVRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAVTIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDTKWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: MT1B_HUMAN
Sequence: MDPNCSCTTGGSCACAGSCKCKECKCTSCKKCCCSCCPVGCAKCAQGCVCKGSSEKCRCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1B, MT-1B, Metallothionein-IB, MT-IB.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: DCUB_HAEIN
Sequence: MSAMFLLQFAIVLLCIFVGARVGGIGLGVFGGLGLAILSFGFGLKPAGLPIDVMFMIMAVVAAAAAMQAAGGLDYMIKIATKILRRNPKHITFIAPAVTWLFTLLAGTGHVAYSVLPVIAEVSRQNGIRPERPMSMAVIASQFAIVASPIAAAVVAVVAYLEPQGIHLGDVLMVTIPSTILGLFLACLFVNKMGKELKDDPEYQRRLNDPKYADIFASTTSVKEVEVSKTAKISVSLFLFGALLVVLMGAAPSIRPVFDGKPMGMAHTIEIIMLSIGALIILTCKPDGTAITKGSVFHAGMRAVIAIFGIAWLGDTLMQAHITEVKEMVKGLVETAPWAFAFALFVLSVLVNSQGATVATLFPLGIALGIPAPVLIGVFVAVNGYFFIPNYGPIIASLDFDTTGTTKIGKYILNHSFMLPGLLSMFFCLLIGLGLSHVIL
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during anaerobic growth.  Catalyzes the uptake of fumarate, malate, aspartate or D-tartrate coupled to the export of succinate.  May function primarily as a C4-dicarboxylate transporter during fumarate respiration.  Required for anaerobic growth on D-tartrate.
What are the official names of this protein?
Anaerobic C4-dicarboxylate transporter DcuB.
What is the protein family that this protein belongs to?
Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBB2_COLGL
Sequence: MREIVHLQTGQCGNQIGAAFWQNISGEHGLDSNGVYNGTSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVAMKDVEDQMRNVQNKNSSYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNATAIQELFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGVDEEEEEYEEEAPLEEEV
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PGK_RIPO1
Sequence: MTKKSIVNLSPADVAGKRVLVRVDFNVPLDGATITDDTRIRAALPTIKDLIEKGAKVILCSHFGRPKGQVVESMRLTPVATRLSELLGQPVVMCDDCIGDSVTAAINQLQNGQVALLENLRFHAEEEANDPEFAQKLAANADLYVNDAFGTAHRAHASTEGVTHYLSPNVAGYLIEKELNYLQAAIENPQRPLVAIIGGSKVSSKIGVIETLLEKCDKLIIGGGMIFTFYKARGLNVGKSLVEDDKLELAKSLEAKAKEKGVDFLLPTDVVLADNFAPDANAKTVSIDAIEDGWMGLDIGPESVKVFQAALADCKSVIWNGPMGVFEFDKFAKGTEAIAHTLAELTGKGTITIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKVLPGIAALDEV
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_HAMD5
Sequence: MAILGMGTDIVEIARVQAIIARSGDKLAHRILTPLELSEYQQHQQPVRFIAKRFAAKEAAAKALGTGFRNGLELRHFQVIHDELGKPHLLVSDKANEMAVRLSVKSWHLSISDERHYAIALVIVEG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NB2_MYCPA
Sequence: MVCALHAVPAHHRRVVTPAGDDPSGPAGSGDRAVAAAAERAKLTAGRNIPSFDDLPLPADTANLREGANLSDALLALLPLVGVWRGEGEGRGHDGDYRFGQQIVVSHDGGDYLNWEARSWRLNDTGDYQERGLRETGFWRFVRDPDDPSESQAIELLLAHSAGYVELFYGRPRTQSSWELVTDALARSRSGVLVGGAKRLYGIVEGGDLAYVEERVDADGGLVPHLSARLSRFAG
What is the function of this protein?
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate.  Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively).  Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
What are the official names of this protein?
Peroxynitrite isomerase 2, Ferric nitrobindin, Nb(III).
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: PLB1_TORDE
Sequence: MNLKEWLLFSDAVFFAQGTLAWSPSNSYTPANVSCDEDINLIRQASGPSDNETEWLKKRDVYTREALRSFLDRATSNFSDSSLVSQLFSNASDIPRIAVACSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQSTTYLAGLSGGNWLVGTLAWNNWTSVQDIVNNMTEDDSIWDISNSIINPGGFMIVTTIKRWDHISDAVEGKQDAGFNVSLTDIWGRALSYNFFPSLYRGGVAYTWSTLRDVEVFQNGEMPFPISVADGRYPGTQIIDLNATVFEFNPFEMGSWDPTLNAFTDVKYLGTKVSNGEPVNKGQCVAGYDNTGFIMGTSSSLFNQFLLQINSTSLPSFIKNLVTGFLDDLSEDEDDIAIYAPNPFKDTSYIQDNFSKSISESDYLYLVDGGEDNQNIPLVPLVQDERNVDVIFALDNSADTDYYWPDGASLVSTYERQFSSQGLNMSFPYVPDKRTFVNLGLADKPSFFGCDAQNLTDLNYIPPLVVYIPNARHSYNSNTSTFKLSYTDDERLKMIKNGFEAATRGNLTDDSSFMGCVACAVMRRKQQSLNATLPEECSTCFTNYCWNGTIDDTPVSGLDNSDFDPTAASSAYSAYNTESYSSSSATGSKKNGAGLPATPTSFTSILTLLTAIAGFL
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Lysophospholipase, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GAS1_ARTBC
Sequence: MKFSSLAAATALVAGSVVAADLDPIVIKVGVRSALIPGWPKGGSKFFYKSNGTEFFMKGIAYQQEFSTNGTSSDKNNYQDPLADVESCRRDIPLMQQLQTNTIRVYAIDPKKDHKQCMKLLQDAGIYVVADLSEPSTSIIRDDPKWDDVLYTRYTSVVDELAQYSNVIGFFAGNEVSNNSTNTDASAFVKAAVRDMKAYIKQKNYRSMGVGYATNDDAEIRKDMTAYFNCNKQEESIDFWGYNIYSWCGDSSYTESGYDKVVEEFKTFNVPVFFAEYGCNEVQPRKFTEVQALYGDKMTPVVSGGIVYMYFQEENDYGLVKIEGGKPKKLPDFNSLQKQISKIKPSGVQMDSYKPTNTALSTCPKSSTWKASVKLPPTPNKDLCSCMVKSLSCVAKPSVTGKELGKLFGTVCGSDKDACKGITADATSGTYGAYSMCSPSEKLSFAFNQYYQHQSAKGNGANACDFGGAATAQKSEKPSGSCANLVDQAGQDGTGSVTSAPGSGGNKPDQGAASTISAPSVNLGIVKLGAYIFCAVLAGAGMILI
What is the function of this protein?
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.  Involved in cell wall biosynthesis and morphogenesis (By similarity).
What are the official names of this protein?
1,3-beta-glucanosyltransferase ARB_07487, Glycolipid-anchored surface protein ARB_07487.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 72 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: RAB8B_HUMAN
Sequence: MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENRSKKTSFFRCSLL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab may be involved in polarized vesicular trafficking and neurotransmitter release.  May participate in cell junction dynamics in Sertoli cells (By similarity).
What are the official names of this protein?
Ras-related protein Rab-8B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: JHD1_CRYNJ
Sequence: MSEQVGQREAVDSPQATGVKTPPEPCPLCRETGPPQPPSITEEGKTNEDIDFIWVACNKCDEWYHSACLFLGDEKWRGTIPKEIISTVETNFGDEGAWTNWVEWIGKWYCAPCLARSTSPSNPRPPRHPLVATMKRASIQPKDIDQAGKPLKRSASTSAPLLKSNIKRPRTSTKGQETASPEIDMKSEREQQAESTAGTPASDAPQGRPKRKTAQIDYRNLNNSIATPTHQWLELIADPEKYGRTILDANYPALPGKLLTRAWLESQPLPGQPSSISPDLLPTRFWGPDREPLIVRPENGGFSSLGGHLPSKDLTVQDVANLVGPDRMVDVIDVSSQHSSQWTLQKWAEYIQSSSGNTSVRNPKVYNVISLEISGTELAKKVKPPKIVREIDWVDNFWRFNAGAGGKDVKEKGRGNDSREGSEIRKEGSHLTEGDNAGGEIEEDLEGLKEKTNTPYPKVQLYCLMGMKGAWTDWHVDFAASSVYYTIHSGAKVKLSCFVSFFSPGSYHSQVFFFVKPTEQNLKAYAEWSGSYEKQQDTWLGDMVDEVRKVELHAGDTMIIPTGYIHAVYTPMDSIVFGGNFLHSYNVDTQLRLRQIEIDTKVPQRFRFPMFDRLCWYVAEKYCSDLRHLRAYRPRATTTPKPPHFRVLQCLSYLANFLVSQTGILEDPEAEDKARKLVHDRIPGDIVKDPEGLAKELKWRVERELGALGLLGEEASGVEAEEFKSNGTANGSVKIKGKEVSRKRDRLSKVFDKKAISRTWDFHPPAWSENRQSPQIETTTVQLPRPSTSSSDAISGSGPGASPGASANGGANENEQAELTTMLVKQTRKRMRELDDGTVIEESQETTFVEKKTIWGPKLDKEKISQPQGKVEEDMDIDH
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
What are the official names of this protein?
JmjC domain-containing histone demethylation protein 1, [Histone-H3]-lysine-36 demethylase 1.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.