PharMolix/UniProtQA huggingface dataset:
Protein: RIBA_AZOVD
Sequence: MSVVFVAASKLPTPFGVFTMHGFLDEATGKEHVALTLGTVDDGAPVLGRLHSECLTGDALFSLRCDCGFQLEAALRAIAAEGRGVLLYLRQEGRGIGLLNKIRAYKLQDAGADTVEANERLGFRADQRDYGICKPMLEHLGITAIKLMTNNPRKVKALEGAGIQVTERVPLQTGLNPHNQKYLATKAGKLGHLLGSLHQGEVETPTGS
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: YNU5_YEAST
Sequence: MHYTNHTKTLKARLFSQRLKTFNKGICRMISRDHSCTLTRSCMKRPIYPRQFFLVLLGETFSLQNSIRHHKNICFKNLNINEFYFFIFISWVTPLVNDASCFFFSSNIRYSALVCSNNYDVKVLETLTKKPLFKRKVLQI
What are the official names of this protein?
Putative uncharacterized protein YNL205C.
Protein: RS10_RICAE
Sequence: MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFANINGPIPLPKKIERFTVNRSPHVHKKSREQFEIRKHKRLLVIGDPNPAVVDALSKVDLAAGVDVVIELESGE
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PSTB1_PSESM
Sequence: MNNLSLANEKTKIQVRGLEFFYNNQKSLKSIDMTIPEKRITAIIGPSGCGKSTLLRVFNRIYAMYPKQEARGEVLLNGENILAPGYSMNRLRSHVGMVFQKPVPFPMSIYDNISYAIKHHEKLSRREMEDRVEQALRGAALWDEVKDKLKQSATGLSGGQQQRLCIARTIALRPQVLLLDEPTSALDPISTGRIEQLITELKEQFTVIIVTHNMQQAARCSDYTAFMFMGELIEHGDTDTIFTKPSKTQTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FTRC_SOYBN
Sequence: MTTQASTFAVAVPSVATPFRRHRNPFVVRAQAEPSDKSVEIMRKFSEQYARKSGTYFCVDKGVTSVVIKGLADHKDTLGAPLCPCRHYDDKAAEVAQGFWNCPCVPMRERKECHCMLFLTPDNDFAGNEQTITLDEIKESTANM
What is the function of this protein?
Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
What are the official names of this protein?
Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, FTR-C, Ferredoxin-thioredoxin reductase subunit B, FTR-B.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin thioredoxin reductase beta subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EAT1_KLUMD
Sequence: MLLAYTVRPSNWSFTRRAYSATARAFNQQKGLLPLPIKETVDMAYDLHLPERSVIGKMPYHSPEPIIFYHGLLGSKRNYRHDCKKLATALQTPVYTVDIRNHGSSEHALPFDYNTLVNDLVHFAETHSLGKVNLVGYSLGAKVAMLACLKHPERFSAACIIDNSPEEQPHIKPLLTALVKSCVKLLDHHNVRADDKLWRHKASEALKKYIPDAGIRYYLLSNIINNPRVVEYRSPVINYDDGMLHFKNPVRHMMDFVTKEVAAWPTQELEGKQFLGPVNFIKATRSDFINPKSLQAINQYFPYHNIDEINATHFILNERPQEYLRAVTDFFKVTRYQLEKKREQDLAKIDQLNASESLKSARD
What is the function of this protein?
Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA (PubMed:28356220).  Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate (By similarity).
What are the official names of this protein?
Ethanol acetyltransferase 1, Acetyl-CoA hydrolase, Acetyl-CoA thioesterase, Alcohol acetyltransferase, AAT, Ethyl acetate esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NS8B_SARS
Sequence: MCLKILVRYNTRGNTYSTAWLCALGKVLPFHRWHTMVQTCTPNVTINCQDPAGGALIARCWYLHEGHQTAAFRDVLVVLNKRTN
What is the function of this protein?
Non-structural protein which is dispensable for virus replication in cell culture.
What are the official names of this protein?
ORF8b protein, Accessory protein 8b, Non-structural protein 8b, ns8b.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: HMGA1_RAT
Sequence: MSESVSKSSQPLASKQEKDGTEKRGRGRPRKQPSVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGTAKTRKVTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ
What is the function of this protein?
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA.  It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts.  They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions (By similarity).
What are the official names of this protein?
High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1.
What is the protein family that this protein belongs to?
Belongs to the HMGA family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FZO1_SCHPO
Sequence: MEKSARQLSVAEQNGESGRLNNGYTSNNIQQYKDETNRHQFEYNQNRNQLLRSIHIIQNLLNELDNYVDRSDCLFHSVWRTDKEKSKFSGNYYPFSPSKMNVITIDLSLRSSSTADEKLISQLGEEAHESLLKVHIEKANKHLFSLFSRVEDTSSKILITGDLNAGKSTLCNALVHKDILPEDQQPCTEVFCEVHDAELNDGKDCVHAIPHGLTYSHTDSSTYKVFPIEDLKRLVYETENWSMLIVYVNDGRPAHESLLHNGITDIALIDAPGLNTDSMKTTSVFACQEEIDVVVFVVNAENHFTLSATDFLRNASTEKSHIFIIVNKFDNIRDKERCKRLILEQIHTLSPGTFADAKDLVHFVSCRVARDPNNREDALYSSFFQMENSLRSFILENRSKSKLAPVRRYLSGLVGDILNICEYNIKLIDFDINHLQQRLTDLSPKFRKVKHEQQFTYQKNESLVEATVQSISQHTHSELEDAIDSLGSFASVKYSGFFFAYQYAISVRDAMQQYLEEKLLESEDYARKRTEEAVLCIQKDVKDNFDSAVLPVFHANQMFIKKHRLQLQKHFRFELGLLDFIDLDLTERLGTWSASLSTILLVLGKTTPSFTTLGAFTGNLGYPIFKYFQNNSLQHLLVPVLGLASICVFGYVIYDIPRALPLKVAEKIKKSLRETDFCHNASIWIGTESRKVLNIPLNDLRRMFHQQWDKQRETISVAENDLRICQKARKFFGEIESRTREAKKKIMMVQLEGCDINY
What is the function of this protein?
Probable transmembrane GTPase, which mediates mitochondrial fusion.  Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondrial morphology, which is balanced between fusion and fission (By similarity).
What are the official names of this protein?
Transmembrane GTPase fzo1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: GPDA_CAMLR
Sequence: MKIAVVGAGKWGSALYDALSVKNECAITSFHEKDLSYFVSTKEALGYEYLVFALYAQGIHEWLVNNFKDLNQKILVASKGIDCKSLKFMDEVFGEFISSDRLCFLSGPSFASEVLEKKPCALVISGKNQNLCSKFASFFPNYIKTYTSLDVKGAEICGAYKNVLAIASGVCDGLNLGNNARASLVSRGLVEMHRFGQFFNAKEETFLGLSGAGDLFLTASSNLSRNYRVGSSLASGKNIKDVLIELGEVAEGVQTAYAIHALSKQFQIYTPIVNEVVLMLEGKNAWESLKDLMSSKEEIS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTX11_LACTA
Sequence: MKYFVVALALVAAFACIAESKPAESEHELAEVEEENELADLEDAVWLEHLADLSDLEEARGFFGNTWKKIKGKADKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYLLKYYGKKALQKASEKL
What is the function of this protein?
Insecticidal, cytolytic and antimicrobial peptide (PubMed:18215128, PubMed:27287558).  Has insecticidal activity against the flesh fly S. carnaria, and against the cockroach N. cinerea (PubMed:18215128).  Has insecticidal activity against D. melanogaster (PubMed:27287558).  Has hemolytic activity against human erythrocytes (EC(50)=6 uM) (PubMed:18215128).  Has cytolytic activity against insect Sf9 cells (EC(50)=1 uM) and human leukocytes (EC(50)=3 uM) (PubMed:18215128).  Has antibacterial activity against the Gram-positive bacteria A. globiformis VKM Ac-1112 (MIC=0. 5 uM), and B. subtilis VKM B-501 (MIC=0. 6-0. 9 uM), and against the Gram-negative bacteria E. coli C600 (MIC=0. 5 uM), E. coli DH5alpha (MIC=0. 9 uM), E. coli MH1 (MIC=0. 5 uM), P. aeruginosa PAO1 (MIC=1. 9 uM), and P. fluorescens VKM B-894 (MIC=3. 8 uM) (PubMed:18215128, PubMed:27287558).  Lacks antimicrobial activity against the Gram-positive bacteria M. luteus and S. aureus, and against the Gram-negative bacterium S. marcescens (PubMed:18215128).  Forms voltage-dependent, ion-permeable channels in membranes (PubMed:18215128).  At high concentration causes cell membrane lysis (PubMed:18215128).
What are the official names of this protein?
M-zodatoxin-Lt8a, M-ZDTX-Lt8a, Cytoinsectotoxin-1a, CIT-1a.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 06 (cytoinsectotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LDOX_ACTCC
Sequence: MVATVVGTRVESLASSGIEAIPKEYVRPQEELTSIGNIFEEEKKENGPQVPTIDLEDLVSEDEEKRVRCHEELKRAATEWGVMQVVNHGIPIELMERVRAAGAEFFNQSVEEKEKYANDHASGNIQGYGSKLANNASGQLEWEDYFFHLVYPEDKRDMSIWPKTPSDYIPATSAYAEHLRGLATKILSALSLGLGLEEGRLEKEVGGMEELLLQMKINYYPKCPQPELALGVEAHTDVSALTFILHNMVPGLQLFYEGKWVTAKCVPDSLVMHIGDTIEILSNGKYKSILHRGLVNKEKVRISWAVFCEPPKEKIILKPLPETVSEAEPPLYPPRTFAQHIHHKLFRKTQELGAK
What is the function of this protein?
Involved in anthocyanin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins (PubMed:30912865).  Required for the accumulation of anthocyanin in red-fleshed kiwifruit varieties (PubMed:30912865).
What are the official names of this protein?
Anthocyanin synthase, AcANS, Leucoanthocyanidin dioxygenase, AcLDOX, Leucocyanidin oxygenase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: DAPD_SALHS
Sequence: MQQLQNVIETAFERRADITPANVDTVTREAVNQVISLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGGESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_SHEWM
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVSERRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IF2_STRPD
Sequence: MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAKKIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAEREARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIERKASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAALKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEEAETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKNSNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKADPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAE1_PONAB
Sequence: MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
What is the function of this protein?
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4.  It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2 (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 1, Ubiquitin-like 1-activating enzyme E1A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: CYF_PINTH
Sequence: MQNRNTYEWAKKMTRLISVLVMIHIITRTSISNAYPIFAQQGYENPREATGRIVCANCHLAKKPVDIEVPQSVLPNTVFEAVVKIPYDMQMKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEIRQKTGNLYFQNYRPNKKNIIVIGPVPGQKYSELVFPILSPDPSTDKEAHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYSASATGRVSKILRKEKGGYEITIDNTSDGGQVVDIVPPGPELLISEGELIKVDQPLTNNPNLGGFGQGDAEIVLQDPLRVKGLLLFLASVILAQIFLVLKKKQFEKVQLAEMNL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ASB3_BOVIN
Sequence: MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSIDVADNRGWMPIHEASYHNSVECLRMLIRADSSENYIKTKTFEGFCALHLAASQGHWKIIQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLRYGANVNGSHSMCGWNALHQASFQGNAEIIKLLLKKGANKECQDDFGITPLFVAAQYGKLESLSILISSGADVNCQALDKATPLFIAAQEGHTECVELLLSSGADPDLYCNEDNWQLPIHAAAQMGHTKILDLLIPLTNRVCDTGPNKVSPVYSAVLGGHEECLEMLLQSGYSPDAQMCLVFGFSSPLCMAFQKDCDFFGIVNILLKYGAQLNELHLAYCLKYERFSVFRYFLKKCCPSTPWDHISEFINHAIKAQTKYKEWLPSLLLAGFDPLNLLCSSWIDSVSDDILIFTLEFTNWRRLPPAVEKMLSARASNSSWALQQHIASVPSLTHLCRLEIWSHLKLEHLQSDGFIRQLPLPRSLHDYLLYAEVLRMNEVPELAVFQDGEISETT
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes TNFRSF1B (By similarity).
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 3, ASB-3.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: ATPE_LIRTU
Sequence: MTLNLCVLTPNRIIWDSEVKEIILSTNSGQIGVLPNHAPIATAVDIGILRVRLNDQWLTMALMGGFARIGNNEITILVNDAEKGSDIDPQEAQRTLEIAEANLSRAEGKRQAIEANLALRRARTRVEAINVISY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GPR27_MOUSE
Sequence: MANASEPGGGGSGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL
What is the function of this protein?
Orphan receptor.  Possible candidate for amine-like G-protein coupled receptor (By similarity).
What are the official names of this protein?
Probable G-protein coupled receptor 27, Super conserved receptor expressed in brain 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_STRP3
Sequence: MTDNSKICVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWHDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVRVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTXC_AGGAC
Sequence: MEKNNNFEMLGYVAWLWANSPLHRNWSLSLLAINVLPAIQYGQYTLLMRDGVPIAFCSWANLSLENEIKYLEDVSSLVYDDWNSGDRKWFIDWIAPFGHNYVLYKHMRKSFPYDLFRSIRVYKGSSEGKITEFHGGKVDKQLANKIFQQYHFELINELKNKSEVISIN
What is the function of this protein?
Required for full activity and modification of the LtxA leukotoxin.  Involved in fatty acid modification of the protoxin at two internal lysine residues, thereby converting it to the active toxin.
What are the official names of this protein?
Leukotoxin-activating lysine-acyltransferase LtxC, Leukotoxin C, Toxin-activating protein C.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELMO1_HUMAN
Sequence: MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Acts in association with DOCK1 and CRK.  Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.  May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
What are the official names of this protein?
Engulfment and cell motility protein 1, Protein ced-12 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Protein: MLTF1_ALKEH
Sequence: MRIMAVRLVAGAITLALMAYAWLAWERARDPEPITILERVLERGELRVITRISATTYYQTDKGRAGLEFELAQAFAHRLGVQLRMLVAPDLEAIFAALDDGEADLAAAGLTYTESRGQRYWFTPPYKDITQQLVYRVGTPRPDDLSEIGPGELAVIANSSHADRLRELRNRSHPDLTWAEDEHADSEAMLYRVWNEELRYTVADSHELSINRAYYPELRKAFEISGVEGLAWAFPRTEDLSLYNEAARYFTDLRLEGTLSTLLEEHFGHLGRFDYVGFRAFNRHVADRLPRYRHWFEEAAEEYGVDWRLLAAIGYQESHWDPQAVSPTGVRGIMMLTLDTASMLGVDNRLDPKQSIFGGARYFSRLLERLPEDIEEPHRAWMALAAYNVGYGHLQDARRLARQRGYDPNDWRVIRDHLPLLSQRQWYVQTRHGYARGWEPVHYVRNIRLYYQLLQRITEPGRRQVPAGEALGEPPLPTPPAPPGAPLPADPPAD
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F 1, Murein lyase F 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: INVF_ARATH
Sequence: MSLSLYDSAHSLDGKSGWDTPVFSMKDSMDRNPMVTEAWEALCQSQVYFRGKPVGTIAAYDHASEEVLNYDQVFVRDFVPSALAFLMNGEPEIVKNFLLKTLHIQGQDKMIDKFKLGDGAMPASFKVLHNPIKKTDTIIADFGESAIGRVAPVDSGFWWIILLRAYTKSTGDHSLAERPECQKGMRLILSLCLSEGFDTFPTLLCADGCSMVDRRMGIYGYPIEIQALFFMALRSALSMLKHDSEGKEFMEKIVKRLHALSFHMRSYFWLDFQQLNDIYRYKTEEYSHTAVNKFNVIPDSIPDWIFDFMPLRGGYFVGNVSPARMDFRWFALGNCIAILSSLATPEQSMAIMDLIEARWEELVGEMPLKICYPAMESHEWGIVTGCDPKNTRWSYHNGGSWPVLLWLLTAASIKTGRPQIARRAIELAEARLLKDGWPEYYDGKSGRFIGKQARKSQTWSIAGYLVAKMMMDDPTHVGMISMEEEKHMKPPLRRSSSWT
What is the function of this protein?
Invertase that cleaves sucrose into glucose and fructose.
What are the official names of this protein?
Probable alkaline/neutral invertase F, A/N-INVF.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 100 family.
Protein: C2GR2_ARATH
Sequence: MRLYVYILQAKDLPAKETFAKLHVGRHKSKTRVARDTSSPIWNEEFVFRISDVDEGDDVVVSILHHEQQDHQSIVSTGLIGKVRIPLTSVAAEENQTLLPTWFVIEKPSDGKFVNIECGKILLSLSLQGKWESTSGEKVLNDKQDIINLEGVKELEGSPKDLISSRDGKRRKHHDGKHIMKNIVNHIDKLFHKKEEISKRLHDESSVGQSVNSNYEDATDQCSSSATCTGFEEGLDLMQSSDSEREEMPENLTGGVLVDQKYLVSPCELNKFLFTPSSQFRKELAELQGLSDVQEGPWTMMQEDTPRLTRVVTYMRAATKMVKAVKATENQVYRKASGKQFAVFVSVSTPDVPYGNTFKIELLYKILPETEPTAGGEASRLIISWGIQFSQSTIMKGMIEGGARQGLKESFEQFSNLLAKTYKTLDPAVVLDKEQVIATVQSEPKTDLKSAFLYFWSSSVICAVLLSVYVVVHMLHCEPSKIQGFEFYGLDLPDSFGELFSSGILVLLLERVYIMTVHFVQARLHRGRDQGVKANGKGWILTIALIKGTNLASVEATELFDPYVVFTCNGKTRTSSVKLQAQDPQWNEVIEFDAMEEPPSVLDVEVFDFDGPFDQGASLGHAEINFLKHTADELADLSVALVGNHAQASQSKLQLRIFLENKNGVETMKDYLSKVEKEVGKKLNIRSPQKNSAFQKLFGLPHEEFLLKEYTCYLKRKLPVQGKLFLSARIVAFYSNVFGHKTKFYFLWEDIDDIQVLPPTFASLGSPLLLIILKKNRGLDAKHGAKSQDDEGRLSFYFQSFVSFDATSRTIMALWKTRTLSVDHRAQIVEEDQDVADPFLLPEAVTVVSDADALMMSKVYTCDLPCDVELVMKIFGGGELERKIMEKSGCLSYASTTWESKKPGVYERRLSYKYNHYVSVFGGGVTCAQQKSPAPNDEGWILNEIVALHDVPFGDHFRVHIRYEVKKAGVDCKTSKCEVYLKIRWLKTIKFEQRISKSIMEKFRNRFKVIFDLFQKESVANSSLTLL
What are the official names of this protein?
C2 and GRAM domain-containing protein At5g50170.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.