PharMolix/UniProtQA huggingface dataset:
Protein: LEP_RICCK
Sequence: MQIDTKTNTNKTTAQEWKSFAFVVCIALLIRILIMEPFTVPTGSMKATILENDYIFSTKYSYGYSNYSLSFFDFIPLFKGRIFACEPERGDIVVFRPPNDMSVRYIKRLIGLPGDKIQLIDDIIYINDKKIERTEVGTYISEEGRKYLKFKETLPNGRTYFSYKLAPIFGVISDDRYGNTDVFYVPEGKYFFLGDNRDQSNDSRVNLGFVPFENFIAKAQFIWFSTKITWWDNDIGVINLILKLKPWIESVRLNRIFRNLYNTDE
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: MTX1_MACFA
Sequence: MAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWRSPSGTLPALRTSHGEVISVPHKIITHLRKEKYNADYDLSARQGADTLAFMSLLEEKLLPVLVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLELLSGEHMPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQAHLRGLHNLCAYCTHILSLYFPWDGAEVPPPRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRALGMAEEDEEE
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.  Essential for embryonic development (By similarity).
What are the official names of this protein?
Metaxin-1, Mitochondrial outer membrane import complex protein 1.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: ECNA_ECOL6
Sequence: MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS
What is the function of this protein?
Acts as antidote to the effect of entericidin B.
What are the official names of this protein?
Entericidin A.
What is the protein family that this protein belongs to?
Belongs to the EcnA/EcnB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ASSY_ECOHS
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLHSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_NITMU
Sequence: MKPRHKKLAIIASSVTALGVASVLVLNAFQSNLVFFFSPTQVANNEAPVGKSFRIGGLVEEGSVKRQADGVTVNFLVTDTAKVIPVVYTGILPDLFKEGKGVVAQGKLASDGIFRADEVLAKHDENYMPPEAAGALDQADKARKTVMQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: YN8E_SCHPO
Sequence: MHQDAMQGSIYEGSRRNTISKPSNNNPPLDMSSLNNDFGQQLDSLATGVGSGSLNGTTNPSSNFNDSNRSNISSSLRSEMEMSNNLLKNTQNDTWTSTVGLSVPENQEAMNFNEGPTGISSIASKNNSSITSKLQNNSNLSVTSSANRGRTSSVSSSYDPSFPWGPRMSSVSSGKQHLSSLSLHTHFNPSSSSTVSSDSLESSQQKAPSSSSTATPASAASEIISNKDPVVEPTHSASNAANSGSNTIRARQTTRTRSNTLPWSPRVFGPTLGYNTPPFGYPPTTSSALPNASGSSSSFFGLPTAVSASAGTSFSDISPAAPKASLENNIASNASSLLNPVGLDHFSAASGWSRDFNHLPASSLATARSSLTGNAKSGIDSSVTGMPSDNYARVVESSTAEFFDPSLASSFGLTNYRTKPLTTGFNHPRPQGHGLNTSLFNTSSGGSLKSPTFEVSNRLGDVDTVPDLPPLGSLSSRPKPSSSSRRRSQSLSAMLKTSNPYMPSPSLLSGSLANSSEHSSSPRLRGSPIHNQPVSSSKSTASLNTNNNGLRASTPEMANISTRSSSESNNTNSWPTVGDATIENLTQHEPTHALWVGNLPSGVSATTVATTFSAYGTVSSIRMLSHKHSAFLNFDSVETAKHVLEELNGKRIFFGSDPVCISFAKVASSSSESSHSAVDGLNKAFSNVSFVPSLREVYDDLINVVQSFGFKDLSKIYQILNAACELTDFAAQIPSISKAFSSRRLNAPKLRQVRKRIDNGLCTQEEVEDIAINWLDEVSDLSSDHLGNTVVQKLFDYCSDPVKEMMLERIAPHLAQIGIHKNGTWAAQKIVDVASTEAQMRLIAKHLQPYIPLLFADQFGNYVVQTCLKFGAPMNDFVFEAILNQFWVIAQSRYGSRAVRACLESPDVTEEQRVLVAAAITVYSVHLAMNGNGTLLLTYLVENMNYPHIPILLTRRFVQDIVRVCTHRLAYNSLLKIISISQGDTACGDLVVDAILDTQNDLNPNSLEKILFEQTYGPSFICKLLTHENISASHRQQLQSAVRNVLGTMEDRGSSELKKLAEVCA
What are the official names of this protein?
Pumilio domain-containing protein P35G2.14.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_CLOAB
Sequence: MRKVMLAEKAGFCFGVKRAVDMALLTQKEYNKKIYTLGELIHNNDVVDKLKDNNVYPIGIEDIDNLKENDVILIRSHGISEEIYKILLSKGLTVINATCPFVTKIQEKVKKYNELGYDIVIVGDKYHPEVIGINGWCDNKAIISKQGENLENITSESKVCIVSQTTEKLENWEKVLKEVKNRAIEVISFNTICNATSERQKIAKDLSNKVDFMVVIGGKQSSNTTKLYEICKSNCNETIHVENSGEIPENILKNKNCVIGVTAGASTPDWIIEEAISKMSENQISNETNNEMADAMKFIAENEGKIYVGASVTGEIIQVSEKEVFLNINYKRDGVIPKSEIDDDGKDLKELFTVGDKIVAKIIKLKDADNYVVLSVKELQREQGYKEIKEAFENKTTLNVVVKEDVKGGIIASYKGIRIFIPASHVELFHVDNLKEYIGKSFDVAIIEYSTKKRQTKIVASRRALLSKEKEKVEETVWNKLEEGQVVEGEVKRLTDFGAFVEIEGVDGLLHVSEISWGRVEKPADVLKIGDKIKVYVLSVDKENKKLSLSVKKLTENPWNNVEEKYPVGSVVLGKVIRFADFGAFVKLEPGVDGLVHISEISHKRIAKPSDALNVGEEIKAKILEVSSEEKKIGLSIREVEE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the IspH family.
Protein: GDL11_ARATH
Sequence: MTTTLLMASLIVSFLLILYYTTIVVASSESRCRRYKSIISFGDSIADTGNYVHLSNVNNLPQAAFLPYGESFFHPPSGRYSDGRLVIDFIAEFLGLPYVPPYFGSQNVSFNQGINFAVYGATALDRAFLVKQGIKSDFTNISLSVQLNTFKQILPNLCASSTRDCREMLGDSLILMGEIGGNDYNYPFFEGKSINEIKELVPLIIKAISSAIVDLIDLGGKTFLVPGNFPIGCSTAYLTLFQTATVEHDPFTGCIPWLNKFGEHHNEQLKIELKQLQKLYPHVNIIYADYYNSLYGLFQEPAKYGFKNRPLAACCGVGGQYNFTIGKECGENGVSYCQNPSEYVNWDGYHLTEATYQKMAQGLLNGRYTTPAFDWSCLGSYDFSG
What are the official names of this protein?
GDSL esterase/lipase At1g28650, Extracellular lipase At1g28650.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLA0_ORYSJ
Sequence: MAIKRTKAEKKVAYDKKLCQLLDEYTKVLIAVADNVGSNQLQEIRKGLRGDSIVLMGKNTLIRRCIKVHADNTGNKEFLELMPLLVGNVGLIFTKGDLKEVREEVAKYKVGAPARVGLVAPVDVVVPPGNTGLDPSQTSFFQVLNIPTKINKGTVEIITPVELIKKGDKVGSSESALLAKLGIRPFSYGLVITNVYDSGSVFSPEVLDLTEDDLMEKFASGVSMVASVSLAISYPTIAAAPHMFLNGYKNVLAVAVETEYSYPHADKIKEYLKDPSKFAVAAPVAADSGAAAPSAAKEEEKKEEPEEESDGDLGMSLFD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, Os60SP0p.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: EUTC_PSEA7
Sequence: MNDKHLPDASAENPWLPLRQLTPARIALGRTGTSLPTRPQLDFQYAHAQARDAVHLPFDHASIGDGLRQRGRDSLLLHSAAADRHVYLQRPDLGRRLDEASVRRLREHAAGYDGQIDLAIVVADGLSALAVQRHTLPFLERLEEQALAEGWSLSPVVLVEQGRVAVADEIGELLRARMSVILIGERPGLSSPDSLGLYFTWAPRVGLTDAYRNCISNVRLEGLSYGMAAHRLLYLMREACRRQLSGVNLKDEAEVQSLEGDAPRTGNFLLARD
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: MINE_ACIF5
Sequence: MSFLDYFLGSRKKSANVAKDRLKLILAHERDADGPDFLPALQEELLAVIAKYIPVDKENIKVSMERRGDFEVLELNVLFPDQH
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MSCL_SHISS
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLAEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTNL_NECSZ
Sequence: MAKIALILGSVRSPRVGNDVTGWVHDVLKSRPSDDLQIEPLVIADFNLPVYDEPVMPAMVPAMKQFTKEHSKRWSAAIASYQGYIFVIPEYNGGIAGGTKNAVDYLYNEWPGKPVAIISYGTQGGNRANAQLSESLELVMKMKVAPTKVLLPFAAGTDVFSAINDGVLGEESQKAWAEAGKKEDILKALDEVKELLKQPKE
What is the function of this protein?
NAD(P)H-dependent FMN reductase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids nectripenoids A and B, as well as cochliquninone D and isocochliquninone E (PubMed:29797385).  The pathway probably begins with the HR-PKS ntnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS ntnG to initiate three more cycles of extension to give a linear hexaketide corresponding to the polyketide part of nectripenoids (Probable).  The FAD-dependent monooxygenase ntnJ then performs an oxidative decarboxylation at C11 of the ntnH/ntnG product, via an electrophilic aromatic hydroxylation with concomitant ipso-decarboxylation (Probable).  The membrane-bound polyprenyl transferase ntnF then introduces a farnesyl group before the FAD-dependent monooxygenase ntnK functions as the first epoxidase on terminal C12'-C13' olefin, followed by a second epoxidation on C7'-C8' catalyzed by ntnA (Probable).  The terpene cyclase/mutase ntnI then initiates the sequential tricyclic ring formation through protonation of the terminal epoxide and catalyzes the regioselective and stereoselective 6/6/6-tricyclic ring formation (Probable).  The cytochrome P450 monooxygenase ntnM may then hydroxylate C1' (Probable).
What are the official names of this protein?
NAD(P)H-dependent FMN reductase ntnL, FMN reductase ntnL, Nectripenoid biosynthesis cluster protein L.
Protein: DHDH_HUMAN
Sequence: MALRWGIVSVGLISSDFTAVLQTLPRSEHQVVAVAARDLSRAKEFAQKHDIPKAYGSYEELAKDPSVEVAYIGTQHPQHKAAVMLCLAAGKAVLCEKPTGVNAAEVREMVAEARSRALFLMEAIWTRFFPASEALRSVLAQGTLGDLRVARAEFGKNLIHVPRAVDRAQAGGALLDIGIYCVQFTSMVFGGQKPEKISVVGRRHETGVDDTVTVLLQYPGEVHGSFTCSITVQLSNTASVSGTKGMVQLLNPCWCPTELVVKGEHKEFPLPPVPKDCNFDNGAGMSYEAKHVWECLRKGMKESPVIPLSESELLADILEEVRKAIGVTFPQDKR
What are the official names of this protein?
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, D-xylose 1-dehydrogenase, D-xylose-NADP dehydrogenase, Dimeric dihydrodiol dehydrogenase, Hum2DD.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: LEUD_SHISS
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: ERF99_ARATH
Sequence: MSSSDSVNNGVNSRMYFRNPSFSNVILNDNWSDLPLSVDDSQDMAIYNTLRDAVSSGWTPSVPPVTSPAEENKPPATKASGSHAPRQKGMQYRGVRRRPWGKFAAEIRDPKKNGARVWLGTYETPEDAAVAYDRAAFQLRGSKAKLNFPHLIGSCKYEPVRIRPRRRSPEPSVSDQLTSEQKRESHVDDGESSLVVPELDFTVDQFYFDGSLLMDQSECSYSDNRI
What is the function of this protein?
Acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
What are the official names of this protein?
Ethylene-responsive transcription factor 13, AtERF13, Ethylene-responsive element-binding factor 13, EREBP-13.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADH1_CAEEL
Sequence: MTVELPSTQRALVFDTWNGPLEVRQVPVPSPADDEILVKIEYSGICHSDLHVWLGDLKDMSVCPLVGGHEGAGSVVQIGKNVTGWQLGDKAGVKLMNFNCLNCEFCKKGHEPLCHHIQNYGFDRSGTFQEYLTIRGVDAAKINKDTNLAAAAPILCAGVTVYKALKESNVAPGQIIVLTGAGGGLGSLAIQYACAMGMRVVAMDHGSKEAHCKGLGAEWFVDAFETPDIVSHITKLTEGGPHGVINFAVARKPMEQAVEYVRKRGTVVFVGLPKDSKVTFDTTPFIFNAITIKGSIVGSRLDVDEAMEFVTRGIVKVPLELVKLEDVPAVYQRMLDGKINSRAVVDFSL
What are the official names of this protein?
Alcohol dehydrogenase 1, Sorbitol dehydrogenase family protein 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ODP23_ARATH
Sequence: MAYASRIINHSKKLKDVSTLLRRENAATIRYYSNTNRAPLNREDTFNSRLGYPPLERISICSTSTLPVSIIFSTTRSNLSSAMGRPIFGKEFSCLMQSARGFSSGSDLPPHQEIGMPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGYLAKIVKAEGSKEIQVGEVIAITVEDEEDIGKFKDYTPSSTADAAPTKAEPTPAPPKEEKVKQPSSPPEPKASKPSTPPTGDRVFASPLARKLAEDNNVPLSDIEGTGPEGRIVKADIDEYLASSGKGATAKPSKSTDSKAPALDYVDIPHSQIRKVTASRLAFSKQTIPHYYLTVDTCVDKLMALRSQLNSFKEASGGKRISVNDLVVKAAALALRKVPQCNSSWTDDYIRQFKNVNINVAVQTENGLYVPVVKDADRKGLSTIGEEVRLLAQKAKENSLKPEDYEGGTFTVSNLGGPFGIKQFCAVVNPPQAAILAVGSAEKRVVPGNGPDQFNFASYMPVTLSCDHRVVDGAIGAEWLKAFKGYIENPKSMLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoamide S-acetyltransferase component 3 of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2 3, PDC-E2 3, PDCE2 3.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL27_SALAI
Sequence: MAHKKGASSSRNGRESAAQRLGVKRFGGQRVNAGEIIIRQRGTKFHPGDLVGRGRDDTLFALAAGSVQFGTKRGRKTVSIVPQQ
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: BIOC_PSEVU
Sequence: MSLVNKRAVAAAFGRAAQSYDSHAQLQRQSADLLLAKLGERRPASVLDAGCGPGSMSRYWRDAGAEVTALDLSLPMLRQAQSQQAAQHYVAADIEALPLADARFDLAWSNLAVQWCNDLGQALKSLHRVVRPGGAVAFTTLASGSLPELHQAWQAVDSRLHANRFLAEETLAETVSAWRGQWGIEPVTLAFDDALAAMRSLKGIGATHLHAGRHNTPLTRGQLQRLQLAWPQQQGRCLLTYSLFWGVIERD
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: ISPDF_BARQU
Sequence: MLAAGRGKRAGSLQKNPKQYRLLGQKPVICHTVRCFCQHPAITTIILVIHPEDRQICEQAITDFKEHLIIVEGGNTRQISTLRGLHALKKFKPKYVHIHDGARPFIENKLLEKIHTTVNHQEGVLPVLPVSDTLKRVNSTHRVLETIPHTHLYSAQTPQCFPFERILAAHERAMQTCKKEFTDDSAIAEWFGIPMHTIPGDSHNIKITWHEDFDTAHLYLKKKMQMFPDIRTGNGYDVHSFEEGTSLILCGIKIPFHKKLKGHSDADVAFHALTDALLATQGAGDIGTHFLPSDPQWKNAPSEIFLRHALEIIKQAGGRIANVDITLIAETPKIGPYRHTMTENLMNILSLSLDRISIKATTNEKLGFIGREEGIAALATATVLYPGEIPK
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: YHZF_SCHPO
Sequence: MGMSLKGQLLTFFGIFITVGPISFLVLKNDLNNKKREYFKLYKQEQAKQLENAKSSKENK
What are the official names of this protein?
Uncharacterized protein C21B10.15.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL32_CORGL
Sequence: MAVPKRRMSRANTRMRRSQWKADNVALQEVKIDGQTVRIPRRLVKAAQLGLVDVEQF
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MDTK_ESCF3
Sequence: MQKYINEARQLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSLLIMLVLWNAGYIIRAMDNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYVFIYGHFGMPELGGVGCGVATAAVYWVMFVAMLSYVKNARSMRDIRNQQHSGKPDTAVMKRLVQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPLSLSAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATVTAIFTVSFREQIALLYNDNPQVITLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYILALTDLVVQPMGPAGFWIGFIIGLTSAAIMMMLRMRYLQRLPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LDHB_RABIT
Sequence: GKFIIPQIVKYSPNCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSRLAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVRGMYGIESEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase B chain, LDH-B, LDH heart subunit, LDH-H.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion inner membrane; Peripheral membrane protein.
Protein: ZNUC_ROSDO
Sequence: MSLVDVDGLSLRYGARTVLSRVSLSIAPGEIVTIVGPNGSGKTSLLRAIIGAVKPFQGRVTRGAGVTLGYVPQKLHIDETLPMTVARFLRLPGGASEAEIDQALAQAGVRDLSGSQLAQLSGGQFQRVMLARALIGKPDLLLLDEATQGLDQRGSASFYQQIEQVRRDTGCAVLMISHELHVVMSASDRVICLNGHVCCEGTPAVVASAPEYRALFGTGTGGALALYRHEHDHEHDHHDGCAHGQATEDRTEAAE
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RETR1_MOUSE
Sequence: MASPAPEEHATQGCPATEEQPPRPGVPGEEAGPEGAGPQVEEAAGRVAAALTWLLGEPVLWLGWRADELLSWKRPLRSLLTFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKEMVLSRTRGAQLWRSLTESWEVINSKPDERARLSQCIAESWMNFSMFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSEADKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFPSLENGTGTNDEDELSLGLPTELKRKKQQLDSAHRPSKERQSAAGLSLPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALTQVAPTAGEDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQSKKSSGFLSNLLGGH
What is the function of this protein?
Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720, PubMed:34338405).  Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720, PubMed:34338405).  Active under basal conditions (By similarity).  Required for collagen quality control in a LIR motif-dependent manner (PubMed:34338405).  Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).
What are the official names of this protein?
Reticulophagy regulator 1, Reticulophagy receptor 1.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS5_CAMFF
Sequence: MEKYNREEFEEVIVDIGRVTKVVKGGRRFRFTALVVVGDKKGRVGFGFGKAKEVPDAMKKAVDDAFKNIVEVKLKGSTIPHDIEVKFNASRILLKPASEGTGVIAGGGARPVVELAGIKNILTKSLGSNNSANVVRATIKALSMLKG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PGK_HELHP
Sequence: MKETGIELMKNTKSVRDIDVKDKRVLIRVDFNVPMDEDFDISDDTRIREALPTINYCIDNHAQNIVLVSHLGRPKGRNAEFSLKHVLKRVERLLGRDIAFAETIENVENLQQQSKSGSVILLENIRFYEGEEKNDEELSTKLASICDVYINDAFGTSHRAHSSTCGIAKYAKECVAGLLLKKEIDSFAKAMANPLKPVLLIVGGSKVSSKLALLYNILDVVDKIIIGGAMSNTFLKARGFDMQKSLVEDDLVSEARKILDKAKEKKVKIYLPVDVVSTDDIKEHRHIKITPAQDIPEGFMAVDMGPATSKLFSEVVRDSQTIIWNGPLGIYEIQAFSRGTFNLAHAVSDTYAFSLIGGGDTADAIDKAGERDNMSFISTGGGASLELLEGKILPAFEVLERK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF5_CANGA
Sequence: MNEEIQTLLIYQICDSLRFQANMEDISVDDVMDVMQENIMVECLLDGVIMDKADVQKIVIQYVTDGELGEEAIGDKMESMYSNSRKKLLKEIDDLDNTISTNRKKDKLLNLYRDTVLNRLQNKKTVLDKLYHGMKEDSSVIRNRIYLERIKNETPNSIAELQLMLQRSIADCIMSEPIGSEKYNIAKEIQINLEDTIRFMKRALE
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF5.
What is the protein family that this protein belongs to?
Belongs to the EAF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XPT_STAA1
Sequence: MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.