PharMolix/UniProtQA huggingface dataset:
Protein: AAEX_SALG2
Sequence: MSLFPVIVVFGLSFPPIFFKLLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HISZ_PSEPK
Sequence: MATVDRWLLPDGIEEVLPPEAARIEIARRQVLDLFQSWGYELVVTPHIEYLESLLTGAGQDLDQRTFKVVDPQSGRLMGFRADFTPQVARIDAHTLRREGPSRLCYAGSVLHAQPRALSTSRSPIQLGAELYGDASPTSDVEVISLMLATLQLADVPDVHMDLGHVGIYRGLARAAGLSGAVEQQLFDAMQRKAVDEVQALTADLPKDLGSMLRALVELCGGREVLAEARVRLGRAPASVLAALDDLLAIADRLASRYPDLPLYFDLGELRGYHYHTGVVFAVFVPGEGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGRAEVVLPTGGIWMPDSGDAALWQQVCQLRNEGQRVVQALPGQPLSAALEADCDRQLIQQDGRWQVLPLAQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKP2_PHYSA
Sequence: VIEPDCKKYEGKKCPPDIALVCGTNGREYYNECALCVFIRDSTLKADKAIKIKKWGKC
What is the function of this protein?
May have a role in mucosal defense against microbes by interacting directly with their membranes.
What are the official names of this protein?
Proteinase inhibitor PSKP-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_METPB
Sequence: MATLQSLADLNRANTQTSNPENEAPVHVQKLDAQGRAYATGKRKDAVARVWIKPGNGTVVVNGRAVETYFARPVLRMILRQPLEIVGRVDQYDITVTVKGGGLSGQAGAVRHGLSKALTYYEPELRSPLKREGFLTRDPRVVERKKYGRKKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: Y101_MYCPN
Sequence: MRDNSAKGITAGSESQQTTYDPTRTEAALTASTTFALRRYDLAGRALYDLDFSRLNPQTPTRDQTGQITFNPFGGFGLSGAAPQQWNEVKNKVPVEVAQDPSNPYRFAVLLVPRSVVYYEQLQRGLALPNQGSSSGSGQQNTTIGAYGLKVKNAEADTAKSNEKLQGDESKSSNGSSSTSTTTQRGGSSGDTKVKALQVAVKKKSGSQGNSGEQGTEQVELESNDLANAPIKRGEESGQSVQLKAADFGTTPSSSGSGGNSNPGSPTPWRPWLATEQIHKDLPKWSASILILYDAPYARNRTAIDRVDHLDPKVMTANYPPSWRTPKWNHHGLWDWKARDVLLQTTGFFNSRRHPEWFDQGQAVADNTQTGFDTDDTDNKKTRLSKGSWLRQAGPDRPPVWSVLRQHWQPHLVRASAFGVWDLFVLIN
What are the official names of this protein?
Uncharacterized protein MPN_101.
What is the protein family that this protein belongs to?
Belongs to the adhesin P1 family.
Protein: PIS2_ARATH
Sequence: MAKQRPATLSVYLYIPNIVGYMRVLLNCIAFSVCFSNKTLFSLLYFFSFCCDAVDGWCARKFNQVSTFGAVLDMVTDRVSTACLLVILSQIYRPSLVFLSLLALDIASHWLQMYSTFLSGKTSHKDVKDSTSWLFRLYYGNRMFMGYCCVSCEVLYIILLLIATNQTENLMNVVVKSLMQISPLSLLLALSIFGWSIKQIINVIQMKTAADVCVLYDIEKQHKKP
What is the function of this protein?
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction.  May thus act to reduce an excessive cellular PtdIns content.  The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity).
What are the official names of this protein?
Probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2, Phosphatidylinositol synthase 2, AtPIS2, PI synthase 2, PtdIns synthase 2.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLYA_HYPBU
Sequence: MLRFWQEKLPLLPQELREVLEKTITHNLWRKYETINLIASENAMSPLALAAYVSDMMHRYAEGKPFKRYYQGTRYVDEIEHRVMQLMGELLGGAHVDPRPVSGTTANASAFRALTNCGDKAVVAPVQAGAHVSHTKFGTLGGLCIEHIEMPYDPENMNIDVDKAIRLIEEVRPRLVVLGGSVYLFPHPVKEIADTAHSVGAKLVYDAAHVLGLIVGRRWRNPLDHGADVMTASTHKTFPGPQGGIVATRSEELYKTISRVVFPVFVSNHHLHRLPALAVTAVEMKYFGEQYADQVVRNAKALAEALAAEGFKVLGEHLGYTKSHQVLVDVRAQGGGAKAATLLEKANIIVNKNLLPYDPPDAIKDPSGLRLGVQEMTRYGMKEDNMKDIARFMRRVLIDGEDPEKVAREVKEYRKEYLEVKYCFDVNPLEDGRLYLLL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP5_ROTHL
Sequence: MSLSIDVTSLPSISSSIFKNESSSTTSTLSGKSIGRSEQYISPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSTQSRSSSNVGCDQLDFSLTKGINVNANLESCISISTDHKKEKSKKDKSRKHYPRIEADSDSEDYILDDSDSDDGKCKNCKYKKKYFALRMRMKRVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: GCSP_ALIF1
Sequence: MSQLLQQLGTDNEFIRRHNGPASSEHQHMLNTIGAETLQQLIEETVPSSIRLPQPMQLPHGLSENAMLAELKQIAQQNTLNTSYIGQGYYNTHTPNVILRNVLENPGWYTAYTPYQPEISQGRLEALLNYQQMVMDLTGLEIANASLLDEATAAAEAMTLCKRGGKSKSNLFFVADDVHPQTLAVIKTRAKFIGFDVVVDHESNLDSHDVFGALLQYPGTTGEVKDLTDLIAQAHTKKTLVIVATDLLASVLLKPVGEMGADIAIGSAQRFGVPMGYGGPHAAFMATREKLKRSMPGRVIGVSIDSKGNQALRMAMQTREQHIRREKATSNICTAQALLANMASFYAVYHGPEGLKTIARRVHHFTAIVAKALQTAGFELEHQHFFDTLTVKTEQQTDILYTKALASSINLRKFDTKLGISFDETTTVSDLVTLLAVFGIDNAECETLSAEVGKDEFAAIPKHCQRTSSFLTHPVFNTYHSETQMLRYLKKLENKDFSLTHGMIPLGSCTMKLNAVAEMLPVTWPEFGGIHPFAPLNQAAGYTTLATSLKSMLCEITGYDEFSLQPNSGASGEYAGLIAIQRYHESRGDAHRNVCLIPSSAHGTNPATASMVSMKVVVVKCDENGNIDMIDLAEKIEKHQENLSSIMITYPSTHGVYEEQVREVCDMVHAAGGQVYLDGANMNAQVGLTSPGFIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKSHLAPFLPGHTENGVQGMDYAVSAADLGSASILPISWAYIAMMGEMGLTEATKVAILNANYVMERLRPHYPVLYRGTNGRIAHECIIDIRPLKETTGISEEDIAKRLMDFGFHAPTMSFPVAGTLMVEPTESEDLAELDRFCDAMIAIREEMNKVEQGEWPLDNNPLVNAPHTQVDLMSDSWEHPYTREVACFPSSQSKDSKYWPTVNRVDNVYGDRNLICSCPSIENYEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MURG_PSYA2
Sequence: MKTPHILMMAAGTGGHVFPALAVSEELSKRGAIIHWLGTPNGMENGLVAPTGYPFHAIEMQGLRGKGIGRLLKMPVTLLSATMAVIKIIRGNKIDMVVGFGGYVSAPGGIAARLTKTPLIIHEQNAIAGMSNRYLAKMATKVLQAFENTFGNDQLDAKLETVGNPVRNAISGVAEPTIRYDINDQSPLKLLVVGGSLGAQVLNDTVPKALALIERPFEVRHQCGRHNEVTTQSAYASEDLSAHEFTVQPFIDDMAAAYNWADIVVCRAGALTVTEIQNVGIAAIFVPLPSAVDDHQTANARTLTLHKAAILLPQNELTPKRLSDELALLDRAACLEMAKKGHALANRQACQHVADIIWQAL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GAG_FSVGR
Sequence: MGQTITTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCEAEWVMMNVGWPREGTFSLDNISQVEKKIFAPGPYGHPDQVPYITTWRSLATDPPSWVRPFLPPPKPPTSLPQPHSPQP
What are the official names of this protein?
Core protein p15.
What are the subcellular locations of this protein?
Virion.
Protein: HIUH2_RHIME
Sequence: MSKSGRLTTHVLDTALGRPAHGLKIDLYRLEGDARHLIRTVHTNSDGRVDGPLMEGAGFATGTYELVFHAGDYFRSAGVKLPDPAFLELVPLRFGIADADSHYHVPLLLSPYGYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase 2, HIU hydrolase 2, HIUHase 2.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: MPH1_SCLS1
Sequence: MSDDEYGDIDAAVWDEAEALTQASQTLPSNFPHRRKRRRIGSEELDDGFLSGRRRGSHGFSRSDNDEADEKKSKYRIHLGAEEVPAAVIMGATQADEMPDSSPYRIRGPIYKRPRRSPPMELEQKSSPAQPSMVESAKTQKQNIVHSPQPTAQYDFSRELEDLPSDAFSPSPPQLRMSSIPITISSSPPLESTQSVRSQRLAAPQNGLRQTTLFGGRAPNQVPSSTQAKKVHKYLVDKVPEPPTHHTLDEEAIKTWIYPNNLGAERRYQYTIVHKGLFNNLLVALPTGLGKTFIAATIMLNFFRWTTDSQIVFMAPTKPLVSQQVKACFEIAGIPRSSTTMLTGDQSPALRAEEWAEKRVFFMTPQTVENDLKTGIADPKKIALIVVDEAHRATGNYAYTKVVQFLRRFNESFRVLALTATPGSSVEAVQEVIDNLEIAEVEIRTEDSIDIKEYVHRRDITEILIDPSDEIIMIRELFSKALQPLVNLLCSQKAYYNKDPMGLTQYGMLTARKAWMASGAGKSAQMSIKGMMNALFTVLTSMGHAIKLLNFHGIGPFFSNIKDFRAEVEGNKKGGKYKNQIVNSPEFKKMMERIQGWINKEDFIGHPKLTYLCDTVLNHFLDAGAGLMGDNMPPSSTRVIVFTEYRDSAEDIARVLNKHGPMIRASVFVGQSDSKRSEGMNQEKQLETIRKFKAGGINVIVATSIGEEGLDIGEVDLIVCYDSSSSPIRMLQRMGRTGRKRAGKIVLLLMRGKEEDSYKKSKDNYEQIQRMISSGSRFTFRHDLSARIIPRKVKPEVDKRFIEIPLENTQDPSLPEPKRRAKPRKKLAKKFHMPDGVETGFRKASKLNSNAESPLTKFGIKRKPSELNDDELAPVPLLDSVLLNAKDEAEHSRRFLKVPDGALEEVGMPDLTAQPITQRTLTRTAKVSHGKYTRSCVSLFNKLSRLQRPEDRDNKPYGDEPPSDFGSIPTMPLEAEVRARAPKAPKASDPAQVVKASRVAKTTSALKKAPASKRVAPKKAKPRRGRALRNDNSDSEDSTASMAMVSNLRSSQIPQPTPDSDEEGPGERVDRTSDMEELEADDDSDLGSLVDFIDPTQTQTQIPLTGTSNFSSSPPLMETWEDERINGNAVGGRRGMLPRAVEMTGAKNSSFKNGTMTQESSDGGDSMDSDFPTIEDLVRSDTTTTTTRKIADPPSSSVFSSGQKATPNMFTRKRDGDVRGRGLKRRVVESDDSDE
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase mph1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB_PSELT
Sequence: MRIRVDLKVDEIPRYWYNVLSDLPFKLDPPLDPKTKQPISPDMLSAIFPMPLIEQEVTDKREIPIPEPVLEEYAVFRPTPLFRATYLEEFLQTPARIYYKYEGASPTGSHKTNTALAQAYYNKISGTERLVTETGAGQWGSALCYSGAKFGLKVNVFMVKISYEQKPMRKYLMRLFDGDVVPSPSEKTSFGKSILASNSENPGSLGIAISEAIEITLSDSRTKYSLGSVLNHVLLHQTVIGLELKKQLEVLGEKPDVILGCHGGGSNFGGTVLPFIPDKLSGKEIKFVACEPTACPSLTRGRYDYDYGDTAGMTPLLKMYTLGKDFIPPKIHAGGLRYHGAAPIISRLVKEGLIEAVAFDQDEIFSAAKLFAKLEGIVPAPESSYAIAGAIREAKKAKEHNIPRVVVFNLSGHGLFDLTAYI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYGB_RALPJ
Sequence: MSTLLIELLTEELPPKALARLGEAFARGLFDGLSAQGLLEEGAAVEGFATPRRLAASITGARRTAPDRELREKVLPVTIAFDAEGKPAAPLVKKLAALAKTVGVEVIAAESLERGPDGKAEALFYRYTARGAVLADGLQTALSQTIANLPIPKVMTYQRPNGENVQFVRPAHKLIALLDSEVIPVSAFGLQSGNVTLGHRFLSAGEIVIQDAASYASTLESQGKVIAGYGKRKEAIRAELLKTAGADTVVMPEALLDEVNALVEWPVVYPCHFEEAFLAVPQECLILTMQTNQKYFALTDAQGHLRNRFLIVSNIATDTPEAIIQGNERVVRPRLADARFFFEQDKKKPLADRVPLLSRVVYHNKIGTQLERVSRLQAIAGQLAEKLGADVAHASRGALLAKADLLTDMVGEFPELQGTMGTYYARHDGEPDDVALACSEHYQPRFAGDALPSTATGTVVALADKLETLVGIWGIGLQPTGEKDPFALRRHALGILRMLIEKPLALTIDDALQIAAASFDGIAAVKPNLAAITDFLYDRLRGYLKDKGYSTNEVEAVVSQRPQRLDDIVARLEAVRAFAALPQAEALAAANKRITNILKKTDVAIGAVQPPLLKEDAERALHQSVVSAEPQVHDAFARGDFTTALKTLAGLREAVDTFFDGVMVMADDTALRDNRLALLAELHGLMNRVADISKLAA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_SYNAS
Sequence: MSDIVRFGVSLDNTLLKQFDRFIKDRNYTNRSEAIRDLIRQELLKKEWTEDQEVAGAITYIYDHHQRDLLNKIIDIQHDFHDVIKSTQHIHLDHDNCLEIVAVKGNPTTISKLSNALKAIKGVRHGSLSISGVGQIA
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: CCA_LACAC
Sequence: MIKIDNLPNIFTKAMPVLQRLEDAGFEAYFVGGSVRDVLLDRHVHDIDITTSAYPEEVKELFEKSIDTGIKHGTVTVLYEGESYEITTFRTESGYQDFRRPDHVTFVQNLDEDLKRRDFTINALAMDIRGQIIDLFNGVEDLKKRVIRAVGNPETRFHEDALRMMRAVRFMSQLEFKLEEKTERAIKDNHELLKKISIERIREEFVKMGLGSHSRQAFQVFLDTQLSEDVPNFAGKKDLLSVYPKLQFSPTMETSLWSIIIILLKMPNESIGKFMRAWKNSNAMTEKVERIINLFDLISEHAPTDYELFQAGEETLINTIDVAHILGQPISSEALVDRYMALPIKKSSELAIDGRFLIEQGMRPGAKLGETLNNIRKLVVSSEIENTQEAIEVYLDELK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: TOLB_ESCF3
Sequence: MKQALRVAFGFLMLWAAMLHAEVRIVIDGGVDSGRPIGVVPFKWAGPGAAPEDIGGIVSDDLRYSGKFNPLDRARLPQQPASAQEVQPAAWSALAIDAVVVGQVTPNPDGSYNVTYQLVDTGGAPGTVLAQNSFKVNKQWLRYAAHTVSDEVFEKLTGIKGAFRTRLAYVVQTNGGQFPYELRVSDYDGYNPFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSELVIQTLANGAIRKVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQITDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGTQNQDADVSSDGKFMVMVSSDGGKQHIAKQDLVTGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MYG_HYSCR
Sequence: MGLSDGEWQLVLNVWGKVEGDIGGHGQEVLIRLFKGHPETLEKFDKFKHLKAEDEMRASEDLKKHGTTVLTALGGILKKKGQHAAELAPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPADFGADTQGAMSKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MURD_LIMF3
Sequence: MKQINDYKGKRVLVLGFGISGLNAAYLLQKLGATVVANDQQVPKDPRVVADLEGAGITAVTGSNPLSLAEEGFDLVVKNPGIPYDTPLVAAFVKKGTPIITELELGYQVFAGHLISVTGSNGKTTTTTLIEQMVAMGNPHRVEYAGNIGVSFSKVAEELGPDDTIVTEASSFQLLGAPTYRPHIAVITNIFANHLDYHKTRQNYIDAKLGITRNQTKDDYLVINWDKEEWQKLAKRTNATVVPFSRLAKSQEGAYQKGGDLYWRQERIMAAKDVVLIGPQNVENALAAIAAAKLSGVANEAIVRVLTTFTGVRHRLQYVLDYEGRRFYNDSKSTDIEATEVALQGFEQPVILLAGGLDRGYTFERLVPYFREHVKALIVFGESKDKMKAAGEQAGVKTIVESTDAVTAVPEAWRLSEPGDVILLSPANASWDQFPNFEVRGDRFIEAVEQLTGKKEEN
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1762_THEPX
Sequence: MSIKLINIGFGNIISANRLVAIVSPESAPIKRIIQEAKNRGMLIDATYGRRTRAVIITDSDHIILSAVQPETVANRLNSNKEILEDTLEEDEEEEE
What are the official names of this protein?
Putative regulatory protein Teth514_1762.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: FEN_THEGJ
Sequence: MGVQIGELVPRKEIELENLYGKKVAIDAFNAMYQFLSTIRQRDGTPLMDSKGRITSHLSGFFYRTINLMEAGIKPAYVFDGEPPAFKKKELEKRREAREEAEEKWHEALERGEIEEAKKYAMRATKLNETLIEDAKKLLGLMGVPVVQAPSEGEAQAAYMAAKKRVYASASQDYDSLLFGAPRLVRNLTITGRRKLPGKNVYVEVKPELIVLEEVLRELGIDREKLIELAILVGTDYNPGGIKGIGPKKALTIVKRSKDPLKKYQKDSDVDLYAIKEFFLNPPVTDDYELKWREPDEEGILKFLCDEHDFSEERVKNGLERLKKAVKAGKQRTLESWFR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: NORR_SALPB
Sequence: MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVVLEEQHFALSEDVLPAPSAESFLALPACRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: ATP8_GORGO
Sequence: MPQLNTTVWPTMIAPMLLTLFLITQLKVLNTNYHLPPLPKTMKMKNFCKPWEPKWTKIYSLHSLPPQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RISB_SACS2
Sequence: MQEKSIRLGIVVAEFNYDITQLMLQKALSHARFLNVEVKVVIKVPGTFDMPLAIKKLLEKDFIDAVVTLGAVIKGETKHDELVASQTARKIVDLSTEFNKPVTLGIIGHGATHEQAVERIEEYATRAVEAAIKLVQRTRKLDELKEIKETVIIE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ATPB_ALTMD
Sequence: MSQGKVVQIIGAVVDIEFPQDAVPRVYDALRVTEGDLSGLTLEVQQQLGGGVVRGIALGTTDGLKRGLTVENTGNPIMVPVGTKTLGRIMDVLGNPIDEAGPIGEEERMSIHREAPSYEDQSSSVELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGFSVFAGVGERTREGNDFYHEMNDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLVIGQEHYDVARGVQTVLQRYKELKDIIAILGMDELSEEDKQVVSRARKIQRFLSQPFFVAEVFTGAPGKYVSLKDTISGFKGILDGEYDHLPEQAFYMVGSIEEALEKAKKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CBID_SALAI
Sequence: MGYDLPPLREPDLPRTAKVRPVALRTGWTTGACATAAAKAALTALVTGVAPAEVEIGLPAGRRVRFPVARCDRRDEGAEAVVVKDAGDDPDVTHGAELTATVGWRPVPGLALEGGPGVGTVTKPGLGLAVGGPAINDTPRRMIGEAVAEVVDLTAVGVRVVISVPRGEIMARKTTNRRLGIVGGISILGTTGIVRPFSTASWRASVVQAVQVAAAQGERTVVLCTGGRTERGARALLPELPEVCFVEVGDFTGAAVTAAVTHGLSGVAFVGMAGKLAKLAAGVLMTHYTRSKVDLSLLGAVTAEAGGTADLATAVTAANTGRHAYELWEAAGLLGPAGDLLCSRVRAVLRRFAGDAVAVDVAMVDFTGARVVASSGRWAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PLSY_CERSK
Sequence: MPAIESGLWALILTGVLGYLLGSIPFGIVITRALGLGDLRKIGSGNIGATNVLRTGNKPAALATLLLDSGKGAIAVLIARAAVGEDAAQLAAFTSFLGHLFPVWLGFRGGKGVATFLGTLLALAWPVGLACCLTWLATAALGRISSLSALVAAASGVLWMILLGYGQMAALGAVLAVLIFIRHHANIRRILAGTEPRIGKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.