PharMolix/UniProtQA huggingface dataset:
Protein: MCH_PANPA
Sequence: AKMNLSSYILILTFSLFSQGILLSASKSIRNSDDDMVFNTFRLGKAFQKEDTAEKSVIAPSLEEYKNDESS
What are the official names of this protein?
Pro-MCH.
What is the protein family that this protein belongs to?
Belongs to the melanin-concentrating hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHEB2_BURO1
Sequence: MNIGIVNDLPLAVEAMRRAIARRPEHRVLWVATDGPQAVELCAAQPPDIVLMDLIMPKFDGIEATRRIMRPERPCAILIVTSCIGANAWRVFEAMGAGALDAVDTPRLGDGAAGDTTKLLLAKIDQIGRLLDAPGSSRLAGAAARGGAGPLIAIGASAGGPGALASILGNLPADFNAPIVIVQHVDRAFAEGMAQWLDGQTRLAVRVAREGDRPQPGVALLAATDDHLRITRAGTLEYTREPAATPYRPSVDVFFNSLTEHWPGRVIGVLLTGMGRDGAIGLKALRMKGYHTIAQDEATSAVYGMPKAAATLGAARAILPLGRIAGELAALARI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
Protein: GTL2_ARATH
Sequence: MFDGGVPEQIHRFIASPPPPPPLPPHQPAAERSLPFPVSFSSFNTNHQPQHMLSLDSRKIIHHHHHHHHHDIKDGGATTGEWIGQTDHDDSDNHHQHHHHHPWCSDEVLALLRFRSTVENWFPEFTWEHTSRKLAEVGFKRSPQECKEKFEEEERRYFNSNNNNNNNTNDHQHIGNYNNKGNNYRIFSEVEEFYHHGHDNEHVSSEVGDNQNKRTNLVEGKGNVGETVQDLMAEDKLRDQDQGQVEEASMENQRNSIEVGKVGNVEDDAKSSSSSSLMMIMKEKKRKKRKKEKERFGVLKGFCEGLVRNMIAQQEEMHKKLLEDMVKKEEEKIAREEAWKKQEIERVNKEVEIRAQEQAMASDRNTNIIKFISKFTDHDLDVVQNPTSPSQDSSSLALRKTQGRRKFQTSSSLLPQTLTPHNLLTIDKSLEPFSTKTLKPKNQNPKPPKSDDKSDLGKRWPKDEVLALINIRRSISNMNDDDHKDENSLSTSSKAVPLWERISKKMLEIGYKRSAKRCKEKWENINKYFRKTKDVNKKRPLDSRTCPYFHQLTALYSQPPTGTTATTATTATSARDLDTRPEENRVGSQDPDISVPMHVDGDGAGDKSNVQFSGFDLEF
What is the function of this protein?
Probable transcription factor that binds specific DNA sequence.
What are the official names of this protein?
Trihelix transcription factor GTL2, GT2-LIKE protein 2, AtGTL2, Trihelix DNA-binding protein GTL2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14_SACEN
Sequence: MAKKSKIARDAQRRAVVARYAQRRAELKRIIAAPGSSPEERAAAQQELRRQPRDASATRLRNRDAVDGRPRGYFRKFGLSRVRLRQLAHSGELPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: COQ4_YARLI
Sequence: MFRTVPKTTLLAPIQRRTLLNGNYPKAYPEHVPLTCLGRAVLAVGSGFGTFFDSRRGDLVATLGEATAQPYFIYKLREQMLKDPTGRRLLREQPRMTSKSLDLDKLRNMKVGSIGRTYVEWLDKEGVSPDTRAQVRYIDDPECAYVMQRYRESHDFYHALTGLPIIMEGELALKAFEWANTGLPMSGLGMVLTPLKFKPKQRKRYFDVYLPWALYNGFRSKPVINVYWEEVLEKDAEELRRDLGIEQPPDLRQMKKDMAKKK
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SELT_BOVIN
Sequence: MRLLLLLLVAASAVVRSDASANLGGVPGKRLKMQYATGPLLKFQICVSUGYRRVFEEYMRVISQRYPDIRIEGENYLPQPIYRHIASFLSVFKLVLIGLIIVGKDPFAFFGMQAPSIWQWGQENKVYACMMVFFLSNMIENQCMSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILDNEMKLNVHMDSIPHHRS
What is the function of this protein?
Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity).  Protects dopaminergic neurons against oxidative stress and cell death (By similarity).  Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity).  Plays a role in fibroblast anchorage and redox regulation (By similarity).  In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (By similarity).  In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity).
What are the official names of this protein?
Thioredoxin reductase-like selenoprotein T, SelT.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein T subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: YL462_YEAST
Sequence: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKVVISVMVGKNVKKFLTFVEDEPDFQGGPIPSKYLVPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAAYT
What are the official names of this protein?
Putative uncharacterized protein YLR462W.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: VPE1_ORYSI
Sequence: MAARCWVWGFVVALLAVAAAADGEEEEGKWEPLIRMPTEEGDDAEAAAPAPAPAAADYGGTRWAVLVAGSSGYGNYRHQADVCHACQILQKGGVKEENIVVFMYDDIAHNILNPRPGTIINHPKGGDVYAGVPKDYTGHQVTTENFFAVLLGNKTAVTGGSGKVIDSKPEDHIFIYYSDHGGPGVLGMPNLPYLYAGDFIKVLQKKHASNSYSKMVIYVEACESGSIFEGLMPENLNIYVTTASNAVENSWGTYCPGEEPSPPPEYITCLGDMYSVAWMEDSETHNLKKETIEDQYELVKKRTSNANKLNEGSHVMEYGDKTFKDEKLFLYQGFNPANGNITNELIWPVPKATVNQRDADLLFMWKRYEQLNGVSEDKLRALREIEDTIAHRKHLDSSIDFIGKLVFGFENGPLALEAARSSGQPLVDNWDCLKKMVRIFESQCGSLTQYGMKYMRAFANICNNGVSEAKMMEASINACGRYNSARWSPMTEGGHSA
What is the function of this protein?
Asparagine-specific endopeptidase that may be involved in processing of proteins targeted to vacuoles (By similarity).  Cysteine protease required for post-translational proteolysis of seed storage proteins in the protein storage vacuole (PSV) of developing seeds, by processing of proglutelin precursor to mature glutelin subunits, thus contributing to the formation of protein crystalline structures in PSV (By similarity).
What are the official names of this protein?
Vacuolar-processing enzyme beta-isozyme 1, Beta-VPE 1, OsVPE1, Asparaginyl endopeptidase VPE1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
What are the subcellular locations of this protein?
Protein storage vacuole.
Protein: BIOB_BURO1
Sequence: MTQAQTAAVQPAAIPVAAPASQRWRVADVVALFELPFNDLMFRAQQVHREHFDANAVQLSTLLSIKTGGCEEDCGYCSQSSHHDTGLKAEKLMDVDTVLDAARAAKANGASRFCMGAAWRNPKERHMPALTEMVRGVKELGLETCMTLGMLEDEQAQQLADAGLDYYNHNLDTSPEFYGQVISTRTYQDRLDTLDRVRDAGINVCCGGIIGMGESRRERAGLISQLANLNPYPESVPINNLVAIEGTPLEGTAPLDPFEFVRTIAVARITMPKAVVRLSAGREQLDDAMQAMCFLAGANSMFYGDQLLTTSNPQTQRDRALFERLGIRASQADALSDNA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TRM61_ASPFU
Sequence: MGSPFLNHRLRSELGDLALLHLRRDQTIPTILKLEDDENQGYKEGKVTNTRFGSFPHSTLIDQPWGSQIVASVVDTGSRGRKNQSSKKRKADDLDTPTSNKDEAQSSPGTPRAAASGFLHLLYPTPELWTASLPHRTQVVYTPDYSYILHRLCVRPGSTIIEAGAGSGSFTHASVRAVFNGYPSEAPAAKKRRLGKVCSFEFHAQRAQRIREEIHDHGLDALVEVTHRDVYEDGFLLGDPKTGKSPKANAIFLDLPAPWLALKHLVRRPPSGAESPLDPSSPVYICTFSPCIEQVQRTITTLREYSWLSISMVEVNHHRIDVKRERTGLDCEGVRGATVFPKSVDEAVAKMRAVEEHSRRFRESLLQESDDEGTASDKPAATKSGKTEVEEKSLQDISQHSDTTAAPSSTPSYDLGRLVHRTEPDLKTHTSYLVFAILPREWTEEDEQRCRQAWPAQKTGGSPDAGKPKGKKQLKREAKEKEVQEEAQKSEDVPARPQETQS
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit trm61, tRNA(m1A58)-methyltransferase subunit trm61, tRNA(m1A58)MTase subunit trm61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_DEHMC
Sequence: MISSLNGILEASGKDWAVINVSGVGFRCYMPATSPALIGGLGQRVRVFTHLHVREDALSLFGFATTEELSLFETLIDVSGIGPKLGLAMLSVMNAEALASAIISGNAELLSTIPGIGKKTSSRIILELKDKIAKNWEAGVLSQVTEANSDILATLTALGYSSSEAAKAISSLGDNGDLPLEERIKLALNYFNNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYC_MYCLB
Sequence: MIDSGHLRLHDTVAGAVRDFVPLRAGHVSIYLCGATVQGQPHIGHVRSGVAFDILRRWLMARGYDVAFIRNVTDIDDKILNKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQMIELIELLIETGHAYTGGSDVYFDVLSYPDYGQLSGHKMDYIHQGEGVTTGKRDQRDFTLWKGAKSGEPSWPTPWGRGRPGWHLECSAMARAYLGSEFDIHCGGMDLVFPHHENEIAQSRAVGDGFARYWLHNGWVTMGGEKMSKSLGNVLSIPAVLQRVRPAELRYYLGSAHYRSMLEFSEAALQDAVKAYVGVENFLTRVRTRVGAVGTGELTPRFAAALDDDLAVPIALAEVHHARVEGNRALDIGDHEGALTNAGAIRAMMGILGCDPLDERWESRDETSAALAAVDVLVAAELESRQMAREQRNWVLADQIRDRLKDAGIEVTDTVNGPQWELLAGDKQVDAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_STRPN
Sequence: MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRDA_ECOLI
Sequence: MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAENPAVAAAEDH
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall (PubMed:3009484).  Responsible for the determination of the rod shape of the cell (PubMed:1103132).  Is probably required for lateral peptidoglycan synthesis and maintenance of the correct diameter during lateral and centripetal growth (PubMed:12519203).
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase MrdA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. MrdA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Localizes preferentially in the lateral wall and at mid-cell in comparison with the old cell pole. Localization at mid-cell is dependent on active FtsI.
Protein: NOP9_YARLI
Sequence: MPREVKKRGRRAAAKRAEEEKEDVDLKVYENDEDYVTFDADGGVAGGHDDEENDGYDNETPYNPLDLKQMPFFGFLDDQESEYFKTAESTLAVDAFGSPEEKLGFISGLLDEARGKELKLVTNQICSKLMERLILLANDEQIRALFEVFSGYFVDLSRHKYSSHCVETLLVRGAAIVEKEVLDPNFDGDSEDSMEKRFLTLANDMKDYIQDLISNPYASHVIRVLLLILGGQTLPSPTSSEGNSSVLRSKKSRTARRNIDIKDSEENDRAYQIPGAFHDALEAIVSGFSKRLKPTAARELAIGQVSSPVVQLLIDSEATTSEQRPLLNTIFADTEDRDSSEEAFVEHLLSDAVGSHFLQNVLQKAPEAFVERLYRLYMSQRVQKLVRRDYAGFVIETCMQRLPEADVHHIIDTAMGEIPYLVENNNLTMVRILLTRAAAANYKATDVANAVLKTFDTDSTDPKLLQKVLQLDEKNPYKPHEASSPGLHRCLVLQQLVEASPEVLATAFVGLNSGDVDVIKMAKHQSYSRLLEKCLRPSINTIERRKFLNKINGQCVDLARDPFASHVMDRLWNFTYKMNNFREKIANELVADEDLKENTYGKAVWRNWSLDKFLRRKSDWWVTLHATDDALAKEYEELGIPLDAKSLANPGQKRFGRGGARIITRGGGTFPRGGGRGRGGFRGGRGGAPRGGFGGSDRGGFKRANGGDGEDASGDRSRKKVRNE
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HIS7_CERS4
Sequence: MRKAEISRKTAETDISVTVDLDGTGRYDIRTGVGFFDHMMDQLARHALIDITLRCEGDLHIDDHHTVEDCGIALGQALTRALGDKRGIRRYGSFHLAMDDALVRAALDLSGRPFLVWNLPFPTEKIGSFDTELVREFFQALATHGGITLHVDLIHGVNSHHIAEAAFKAVARSLREAVEPDPRRADAIPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_STUS1
Sequence: MSQVTMRDMLKAGVHFGHQTRYWNPKMDKYIFGARNKIHIINLEKTLPMFNDALRFVEKLAAGKNKILFVGTKRSAGKIVREEAARCGSPYVDHRWLGGMLTNYKTIRASIKRLRELEAQSQDGTFEKLTKKEALMRTRDLEKLERSLGGIKDMGGLPDAMFVIDVDHERIAISEANKLGIPVIGVVDTNSSPEGVDYIIPGNDDAIRAVQLYLGSMADAVLRGRQNGAGGADEFVEEVASEAAQG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: OPSG_GEKGE
Sequence: MTEAWNVAVFAARRSRDDDDTTRGSVFTYTNTNNTRGPFEGPNYHIAPRWVYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVASTISVFNQIFGYFILGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGNIKFDSKLAIIGIVFSWVWAWGWSAPPIFGWSRYWPHGLKTSCGPDVFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQKESESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAANPGYAFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLFGKKVDDGSEASTTSRTEVSSVSNSSVAPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Green-sensitive opsin P521, Green photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MAGAC_HUMAN
Sequence: MPLEQRSQHCKPEEGLEAQGEALGLVGAQAPATEEQETASSSSTLVEVTLREVPAAESPSPPHSPQGASTLPTTINYTLWSQSDEGSSNEEQEGPSTFPDLETSFQVALSRKMAELVHFLLLKYRAREPFTKAEMLGSVIRNFQDFFPVIFSKASEYLQLVFGIEVVEVVRIGHLYILVTCLGLSYDGLLGDNQIVPKTGLLIIVLAIIAKEGDCAPEEKIWEELSVLEASDGREDSVFAHPRKLLTQDLVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHLLKISGGPHISYPPLHEWAFREGEE
What is the function of this protein?
Not known, though may play a role tumor transformation or progression.  In vitro promotes cell viability in melanoma cell lines.
What are the official names of this protein?
Melanoma-associated antigen 12, Cancer/testis antigen 1.12, CT1.12, MAGE-12 antigen, MAGE12F antigen.
Protein: PHS_SHEB2
Sequence: MTALSNMKCEACQADAPKVTDEELAELIRMIPDWGVQVRDGVMQLERVYKFKNFKLAMAFTNKLADLAEEEFHHPGIFTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLV
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: GDX_SALTI
Sequence: MSWIILLIAGLLEVVWAVGLKYTHGFSRLTPSIITITAMVISMALLSWAMKTLPVGTAYAIWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLSAH
What is the function of this protein?
Guanidinium ion exporter.  Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons.
What are the official names of this protein?
Guanidinium exporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDH_SHESM
Sequence: MKALSKLKAEKGIWLVDAPKPEMGHNDLLIKIKKTAICGTDMHIYNWDEWSQKTIPVPMVVGHEYVGEVVDIGQEVRGFKIGDRVSGEGHITCGHCRNCRAGRTHLCRNTSGVGVNREGSFAEYLVIPAFNAFKIPDDISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVCRHVGARHVVITDVNEYRLELARKMGATRAVNVAQESLKDVMKELGMTEGFDVGLEMSGVPSAFHAMLDTMNHGGKIAMLGIPGGEMAIDWSKVIFKGLVIKGIYGREMFETWYKMASLIQSGLDISPIITHHYKIDDFQKGFDAMGSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_AZOSB
Sequence: MDAQVGDNPVAQAIAHALVEGFNKHYRIFRGTSRRAKEYFEAGDWRAQLDAVRDRVQFYDDRVDETVRRLLEEFDADSLDDATWQQVKLHFIGALINHKQPELAETFFNSVGCKILHRTYFNNDYIFARPAISTEYIESYPPVYSSYYPQDGGLRATIRRIIEDFDWQRPFEDLDRDIDCIMRAALAHLGEWPAMEVNCQLQVLYSAFYRNKTAYIIGKVINGWQDYPFTLAVRHGASGRLVIDTILLDPWRISVLFSLSRAYFMVDMEVPSGYVQFLRSIMPNKPRSELYTMLGLGKQGKTMFFRDLVAHLRHSNDQFIIAPGIRGLVMLVFTLPSYPYVFKIIKDVFGSSKNMDRATVKRKYLMVKQVDRVGRMADTLEFSYAALPLSRFHPELLEELRTLAPSAFEIDGDALVLKHFYIERRMTPLNIHLEKASDGEVEAAVHEYGNAIRELAIANIFPGDMLWKNFGVTRYGRVVFYDYDEIEYMTSMNFRRIPPAPHEDMELSGEPWYSAGPMDVFPEEFATFLLGSPRVRKAFMKYHRDLLEPAFWQAAQQGVRDGHVEDFFPYPAELRFSVMFPATPVAAQD
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC13_ASPCL
Sequence: MIHDAGLDYYGRRLATCSSDKTIKIFEIEGETHRLAETLKGHEGAVWCVAWAHPKFGTILASSSYDGKVLIWREQHQSPTSPAAGSAWTKVFDFSLHTASVNMVSWAPHESGCLLACASSDGHVSVLEFRDNSWTHQIFHAHGMGVNSISWAPAAAPGSLISSNPGPGQQRRFVTGGSDNLLKIWDYNPESKTYNITQTLEGHSDWVRDVAWSPSILSKSYIASASQDKTVRIWTSDASNPGQWTSQQLEFDTVLWRVSWSPSGNILAVSGGDNKVSLWKENLKGQWEKVKDIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein sec13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: PHAG1_HUMAN
Sequence: MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL
What is the function of this protein?
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.  Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition.  Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.  May be involved in cell adhesion signaling.
What are the official names of this protein?
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp.
Protein: RIP_SIRGR
Sequence: DVTFSMLGANGATYYQFF
What is the function of this protein?
Inhibits protein synthesis in the rabbit reticulocyte lysate system.
What are the official names of this protein?
Ribosome-inactivating protein momorgrosvin, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: GCSH_THIDA
Sequence: MSIPADLKYTQSHEWVRAEADGSVTVGITHHAQDLLGDMVFIENPAVGRTLAKGEECAVVESVKAASDVYAPVAGEVIAANGEVESSPESVNQDAYTAWLFKIKPANPADVDALLDAAAYQKVVESEAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: F16PA_HALWD
Sequence: MASSIDSHMTESTADSESESFSLTDDEIINSILDILARTAPEIRNGLPGRRVKTNEENPSGESPMEADVFADELLRNRLGSLDGIGEYASEERSSADDTGSGLSVCIDPLDGSSNLKSNAAMGTIAAVYDAPLPARGSDLVAAAYVLYGATTTMIAAVEGNVADYVIYQDGSYEPIEQEVRVPSEPTVYGFGGRVPNWPRDFNSFVSDIESDTSMKLRYGGAMVGDVNQVLTYGGIFGYPALTNAPSGKLRVQFEGYPIGYIIECAGGASSDGSQSLLAVESNDIHDRTPVYVGTPSLVERLEGALAGKADSE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1306_LISMO
Sequence: MWIYILVGIICLLAGLAGGFFIARRYMMSYLKNNPPINEQMLQMMMAQMGQKPSQKKINQMMSAMNKQQEKEKPKKAKK
What are the official names of this protein?
UPF0154 protein lmo1306.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.