PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_ALKMQ
Sequence: MELVIAKHAGFCFGVEKAINTAFKEIKNNQKNNSIYTLGPLIHNNQVVSSLESHGVYTKDSISEIDDGSVIIRSHGVSKATYGLAEEKNLNIIDATCPFVKKIQNIVEEYFNKGYKIAIIGNPEHPEVIGINGWCNNEAYTVQQITDVDLIPKLDKVCIVVQTTMPIVQYEELSTLISTKSNQVEQFNTICHATKERQESAKLVSQEVDAMIVIGGYHSSNTQKLVAICKEEKPLDTYHIETVVDLDLEALQNYNRIGITAGASTPIWIVDEVVKSLRNL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: HSLV_PSEFS
Sequence: MTTIVSVRRHGKVVMGGDGQVSLGNTVMKGNAKKVRRLYHGQVLAGFAGATADAFTLFERFEGQLEKHQGHLVRAAVELAKEWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEHGLIAMGSGGGYAQAAASALLKKTDLSAREIVETALGIAGDICVFTNHNQTIEEQDLAE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_YEAST
Sequence: MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYSFVHLSAGDLLRAEQGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDVQDAIRDSL
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP, AMP, GMP, dGMP and dTMP.  ATP and dATP are the best phosphate donors, but can also use GTP, dGTP, dCTP, and dTTP to some degree.
What are the official names of this protein?
Uridylate kinase, UK, ATP:UMP phosphotransferase, Deoxycytidylate kinase, CK, dCMP kinase, Suppressor of cdc8 protein, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: NRG2_HUMAN
Sequence: MRQVCCSALPPPPLEKGRCSSYSDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVVVEGKVQGLVPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQVISVGSCVPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLYVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIEGINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVGTSKCNSPACVEARARRAAAYNLEERRRATAPPYHDSVDSLRDSPHSERYVSALTTPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYPAAGPGPRRGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADDADGALAAESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQDSAPL
What is the function of this protein?
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors.  Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.  May also promote the heterodimerization with the EGF receptor.
What are the official names of this protein?
Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-2]: Secreted.
Protein: FUCI_PHOV8
Sequence: MKKYPKIGIRPTIDGRQGGVRESLEDKTMNLAKAVAELISSNLKNGDGSPVECVIADSTIGRVAESAACAEKFEREGVGATITVTSCWCYGSETMDMHPHWPKAVWGFNGTERPGAVYLAAVLAGHAQKGLPAFGIYGHDVQDLDDNTIPADVAEKLLRFARAAMAVANMRGKSYLSFGSVCMGIAGSIVDPDFFQEYLGIRNESVDETEILRRMEEGIYDHEEYAKAMAWTEKYCKPNEGEDFKNRPEKRKTREEKDADWEFIVKMTIIMRDLMVGNPKLLEMGFKEEAIGHNAIAAGFQGQRQWTDWKPNGDFSEALLNTTFDWNGIREAYVLATENDACNGVAMLFGHLLSGCGQMFSDIRTYWSPEAVKRVTGKELTGMAKNGIIHLINSGATTLDATGESHNEAGEPCMKPNWEMTEADVEACLKATTWYPADRDYFRGGGFSSNFLSKGGMPVTMMRLNLVKGLGPVLQLAEGWTVDIDPEIHQVLNMRTDPTWPTTWFVPRLCDKPAFRDVYSVMNNWGANHGAISYGHIGQDLITLASMLRIPVCMHNVEDDKIFRPASWNAFGMDKEGSDYRACSTYGPIYK
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_ECO24
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL14_SHESM
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNNNLQPIGTRIFGPVTRELRNEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ANMK_FRATN
Sequence: MSEYKYCVGIMSGTSLDGIDVALCKIRGSGLDTDVKLIDCQTYPYPTNLLCDIKKSLDLSTSNAQLLCSLNFKLGIEYANAVKKLVAANNLNLKDIAFIASHGQTIYHQANNERGFIKSSLQLGDAATIAYECQTTVVSNFRAGDIAAGGDGAPLVPYVDYLLYRDKDKSRALHNIGGIANTTIIPKNANIDDIYAFDTGPGNMMINRSMEVLFNQDYDKGGDTAAAGIVIVDMLQELLDNPYLKQKPPKSTGRELFGINYTDKIIAKYKQNKPEDIVHTLTIFTAQSIVRAYKDFVFNKNKLDQIIFTGGGAYNKFLIKTISDLLDVEVLTFEDIGESSDAKEAIAFAVLGNETLNKSYNNIPSATGAKSRVILGQINFF
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RPOA_AMBTC
Sequence: MVRKEVPVSNRTLQWKCVESKADSKRLYYGRFVLSPLMKGQADTIGTAMRRSLLGEIEGTCITCAKSERVPHEYSTIVGIEESVHEILMNLKEIIVRSDLYGTRDAFICVRGPKYVTAQDIISPPSVKIVDTTQHIASITEPINFCIGLEIERNRGYRTRTTNQDASYPIDAVSMPVRNANYSIQCYGNENEKQEILFLEIWTNGSLTPKEALYEASRNLIDLFIPFLHAEERDLHLDDDQNIFTAPFFPFHEGLAYIGIGESKKRIALKRIFIDQLELSPRTYNCLKRSNIHTLLDLLSKSQEDLRKIQHFRVEDVKRVLDILKKRFAMNLFT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VSPS1_TRIST
Sequence: MELIRVLANLLILQLSYAQKSSELIIGGDECNIDEHRFLVALYKSGRFRCGGTLINQEWVLTAAHCDRRNMEIKLGMHSKNVPNEDEQRRVPKEKFFCDSNKNYTQWNKDIMLIRLNSPVNNSTHIAPLSLPSSPPIVGSVCRIMGWGTITSPNETYPDVPHCANINLFNYTVCHGAHAGLPATSRTLCAGVLEGGKDTCKGDSGGPLICNGQFQGIVSWGGHPCAQPREPGVYTKVFDHLDWIQNIIAGSTTATCPL
What is the function of this protein?
Snake venom serine protease.  Degrades concomitantly alpha- (FGA) and beta-chains of fibrinogen (FGB).
What are the official names of this protein?
Alpha- and beta-fibrinogenase stejnefibrase-1, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
Protein: SYS_BUCBP
Sequence: MLNPNLLRNHIEFVFKNLARRGFSLDVKQFTEMEKKRKILQTKVEELQSRHNTLSKHIGRIKLIHPNIQCMKERIITLKKKIDVMKKELKILLEQIHIFLMNIPNLPDINIPDGMGSDDNQEVSRWGIIKNYNFKIKNHVELGNHLNGFDWKSAANISGSRFFIMKGKIALLYRVLGQFMLDLHTNEHGYLETYVPCLVKTNNLYGTGQLPRFKTDLFYAKSLLDESQNNNNFALIPTAEVPLTNLFRDCILDEQQLPIMLVAKTPCFRSEALSYGRDTQGLIRTHQFDKVEIVQIVHPSDSMQKLEELTIHAERVLKLLKLPYRKTLLCTRDIGFSSSKTYDLEVWFPSQNVYREVSSCSNMLDFQARRIKARFHCNAQNKKIFIHTINGSGLAVGRTLAAILENYQQKDGRIKIPKILRNNYMNGLEFLE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JSN1_YEAST
Sequence: MDKSKQMNINNLSNIPEVIDPGITIPIYEEEYENNGESNSQLQQQPQKLGSYRSRAGKFSNTLSNLLPSISAKLHHSKKNSHGKNGAEFSSSNNSSQSTVASKTPRASPSRSKMMESSIDGVTMDRPGSLTPPQDMEKLVHFPDSSNNFLIPAPRGSSDSFNLPHQISRTRNNTMSSQITSISSIAPKPRTSSGIWSSNASANDPMQQHLLQQLQPTTSNNTTNSNTLNDYSTKTAYFDNMVSTSGSQMADNKMNTNNLAIPNSVWSNTRQRSQSNASSIYTDAPLYEQPARASISSHYTIPTQESPLIADEIDPQSINWVTMDPTVPSINQISNLLPTNTISISNVFPLQHQQPQLNNAINLTSTSLATLCSKYGEVISARTLRNLNMALVEFSSVESAVKALDSLQGKEVSMIGAPSKISFAKILPMHQQPPQFLLNSQGLPLGLENNNLQPQPLLQEQLFNGAVTFQQQGNVSIPVFNQQSQQSQHQNHSSGSAGFSNVLHGYNNNNSMHGNNNNSANEKEQCPFPLPPPNVNEKEDLLREIIELFEANSDEYQINSLIKKSLNHKGTSDTQNFGPLPEPLSGREFDPPKLRELRKSIDSNAFSDLEIEQLAIAMLDELPELSSDYLGNTIVQKLFEHSSDIIKDIMLRKTSKYLTSMGVHKNGTWACQKMITMAHTPRQIMQVTQGVKDYCTPLINDQFGNYVIQCVLKFGFPWNQFIFESIIANFWVIVQNRYGARAVRACLEAHDIVTPEQSIVLSAMIVTYAEYLSTNSNGALLVTWFLDTSVLPNRHSILAPRLTKRIVELCGHRLASLTILKVLNYRGDDNARKIILDSLFGNVNAHDSSPPKELTKLLCETNYGPTFVHKVLAMPLLEDDLRAHIIKQVRKVLTDSTQIQPSRRLLEEVGLASPSSTHNKTKQQQQQHHNSSISHMFATPDTSGQHMRGLSVSSVKSGGSKHTTMNTTTTNGSSASTLSPGQPLNANSNSSMGYFSYPGVFPVSGFSGNASNGYAMNNDDLSSQFDMLNFNNGTRLSLPQLSLTNHNNTTMELVNNVGSSQPHTNNNNNNNNTNYNDDNTVFETLTLHSAN
What are the official names of this protein?
Protein JSN1, Pumilio homology domain family member 1.
Protein: GPMI_BACSU
Sequence: MSKKPAALIILDGFGLRNETVGNAVALAKKPNFDRYWNQYPHQTLTASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAISNAKENNKALHLFGLLSDGGVHSHINHLFALLKLAKKEGLTKVYIHGFLDGRDVGPQTAKTYINQLNDQIKEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSALDVVDDSYANGIYDEFVIPSVITKENGEPVAKIQDGDSVIFYNFRPDRAIQISNTFTNKDFRDFDRGENYPKNLYFVCLTHFSETVDGYVAFKPINLDNTVGEVLSQHGLKQLRIAETEKYPHVTFFMSGGREAEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIEADKHDAIILNFANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAILAKGGHAIITADHGNADILITESGEPHTAHTTNPVPVIVTKEGITLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK
What is the function of this protein?
Essential for rapid growth and for sporulation.  Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM, Vegetative protein 107, VEG107.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: GPDA_ACIBC
Sequence: MAEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEINKTHINKRYLPDFTLESSLRAVSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVVSLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIMAGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSRFAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGINTIVQVRGKAQELDVYMPITNALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI214_AETCO
Sequence: MMVFQSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMDEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNHKHFFDYGSTTRNEMRNLRIQCVFLNNLIFQLFNHFILPSSMLARLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLVLVWIQQNHSIRSNVLIRSNKYKFLVSELRNSMARIFSILLFITCVYYLGRIPSPIFTKKLKGTSETEERGGTKQDQEVSTEEAPFPSLFSEEREDLDQIDEIDEIRVNAKEQINKDDEFHIRTYYNYKKVSENLDGNKENSNLEFLKIKKKEDSVLWFEKPFVTLVFDYKRWNRPNRYIKNDQIENAVRNEMSQYFFSACQSDGKDRISFSYPRNISTFFDMIQKKIPSFRREKTPSDKFSTCWSLINEEKKENLKKEFLHRIEALDKEWSVEHILEKTTRFCHNETRKEYLPKIYDPFLQGISRGRIQRLVPFQIITETYIKNNIGRSWINKIHGILLNINYQKFEQTIEKFNRKSSAIEKKLSYFFDPQEEKLNSEEEIKIFKFLFDVVLTDSNDQMLSKNFLDVHEIHKKVPRWSYKLRSDLEELEGENEETIPMEPGIRARKAKRVVIFTDTEPHNEIYTNLKNNQNYDQNDEMVLIRYSQQSDFRREIIQGSMRPQRRKTVIWEFCQANMHSPFFFDKIGKFFFFSFDIRGLTKKILRNFMWKNGKKKLDKKYEDKSKRKEKRRLEIAEVWDSFLFAQILRSSLLVTQSILRKYIILPLLIIIKNSVRMLLFQIPEWSEDLKDWKREMHVKCTYNGVQLSETEFPRKWLTDGIQIKILFPFYLKPWHKSKFHSSQKGRLKKTKDKNDFCFLTVWGMETELPFGSAQKQPSFFEPFFKEFKKKMKKYKTKSLLVLRFFKERDKIFAKEIKNGILKNFIFIKGKRNDLSKGNRIPLFDLREIYELTETKNDSITSNPIIHELSVQNRSMEWKNSSFSENKIKNLIDRINTIRNQIEAISKEKKKITNSSNKTPYESKIIESSKKKWQIVKRINTRLIRKIFYFVKFCLEQLSLGIVVGIMNIPRMTTQFFFESTKKILDKSIYKNEETEDKITKKKNTIYLISTIKKLISNKKKMSYDICSLSQAYVFYKLSQLQVSNFSKLRAVLEYNICGTSLFVTNQIKDFFQKHGIFHYKLKEKTFLNSEINPWKNWLRSHYQYNLPEIVWARLVTEKWKNQINQNSLVLNKSLNKEDSYEKNKFDNYKKLNYLKADSLLNPKQKQNFKKDSIYNIFCYKSINSKEKSFDMPLEIIIDNFLVSSFRGKSNIRDIGEFRTRKYLEWRIIPFWFIKKVNIESAVDTKSQKIYIKTQVQNSEKIDKITKMGLANQKSLFFDWMGMNEEILNYPIANLEFLFFPEFFLFSSTYKIKPWVIPIKLLLFNFNEKKNLNKIITRNKNGFIPSNEKKYLRFYNLTNDEKEKQRNPQLALPNQEKNIEENYAESKIKKRQNKKQYKSNTEVELDLFLTRYSRFQLRWNFFLNKKILNNVKIYCLLVRLKNPNKIAISSIERGEMSLDILMIEKNLTFAKLMKKGILIIEPLRSSVKNDGQLIIYRTIGISLVHKNNHQISQRDKKKIEKSITQLKKKTVNRKKNNYDFFVPEKILSPKRRREFRILICSKLKKKSTRYRNSRFDKNIQNCGQVLNQTKYLDNDKTNLINLKFFLWPNFRLEDLACMNRYWFNTNNGNHFSMIRIHMYTRLKINS
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: H2AX_XENLA
Sequence: MSGRGKAVSKTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAHRVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKSRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKSSGGVSTSGKKSSQQSQEY
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
What are the official names of this protein?
Histone H2AX, H2a/x, Histone H2A.X.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MAP11_DICDI
Sequence: MEGILCASPGCGKPAKLQCPTCVNLKLETPSHFCSQECFKTFWPLHKMYHQKGQPENLPSQFRNYKFTGPLRPTNITPMRKAPEGIELPDYAIGSIPISERVADRKNMANIIHTPEEIEIMRQLGKMSREVLDIAGNAAKVGMTTEELDIIVHNAVIERGAYPSPLNYYKFPKSCCTSLNEVICHGIPDERPLRDGDILNVDVTLYWKGFHSDLNETYLIGNVDERGKNLVKCAYDCLELAVAMCKPGTLYRELGDAIQKHANKQGFSVVKNFCGHGIGRLFHCNPTVPHYSKNKAVGAMKVGHVFTIEPMINEGTWQDEIWPDSWTAVTADGKRSAQFEHTLVITETGCEVLTKRTNGSYIDRHFK
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3270_ARATH
Sequence: MAERQQSPAAETIPGTPVIREVRTGTGSENFNPENTRRGCLRAEIDISPQLYGGRGFWVPFNLEDNYDCVGEFDIKRMEEQTVELEKDLIMKELETLDLLEALGSTKRIFEDLKWQLQQQALRCKETPQHLRSHSKEMVDEHCHRNPLKSPDLMTMEMKQAGMNLCKTMDDLALIHSYAESLNMKTKEEKDVLGVASLAEELNSLKFKPAGPDQVERFNTENLPVNPQCEQIKMVVETYDTAFHKQSKTCPRTADMRLVAARKMEEAARAAEALALAEMTILSSRRNQDALCFPKTPCFPLTLKAQMNKELSTNVSRIEILRKLEEANEEVKQSKQALEVALNRVEIASVKQLEAEEAFRQWNIESWKDQKAVGAKRSMKRESFPQRSFLSHINQHEPLIDLPEPMLKRNVSMGNALNRKDEKQLVTPRRKFRFIQTHQASIRKTE
What are the official names of this protein?
WEB family protein At3g56270.
What is the protein family that this protein belongs to?
Belongs to the WEB family.
Protein: RISB_SULDN
Sequence: MKLIEGQLKVVNGKKVAIVSTRWNHFIVDRLVEGAKDAFARHGGDEADLTHVLVPGAFELPMIIDKLLASGKYDAICALGAVIRGATPHFDYVSAEATKGIAMMSLKHQKPVSFGLLTTDNIEQSIERAGTKAGNKGFEAMTVVIEMLDLYENL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: GUAC_ECOUT
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: ACCH6_ARATH
Sequence: METKEFDSYSERKAFDETKTGVKGLIDAHITEIPRIFCLPQGSLSDKKPFVSTTDFAIPIIDFEGLHVSREDIVGKIKDAASNWGFFQVINHGVPLNVLQEIQDGVRRFHEEAPEVKKTYFTRDATKRFVYNSNFDLYSSSSCVNWRDSFACYMAPDPPNPEDLPVACRVAMFEYSKHMMRLGDLLFELLSEALGLRSDKLKSMDCMKGLLLLCHYYPPCPQPDLTIGTNNHSDNSFLTILLQDQIGGLQIFHQDCWVDVSPIPGALVINMGDFLQLITNDKVISVEHRVLANRAATPRISVASFFSTSMRPNSTVYGPIKELLSEENPSKYRVIDLKEYTEGYFKKGLDGTSYLSHYKI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 6.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: KATG_SHIFL
Sequence: MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGAYFDGSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL18_POLNA
Sequence: MLTKKEQRLRRSRQTRIRIANQGVARLSVNRTNLHIYASVISGDGTKVLASASTAEVEVRNEIGGSGKGGNVAAAQAIGKRIAEKAKAAGVEKVAFDRAGFAYHGRVKALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL10_JANSC
Sequence: MDRAQKEKVVEELGQIFESSGVVVVAHYQGLTVANMQDLRGRVRDAGGAVRVAKNKLAKIALDGTDVAGISDLMTGMTVLAYSDDPVAAAKAADEFAKENDNYVILGGAMGENILDADGVKAVAKMPSREELISSIAGCIGAPAANIAGAIGAPASNIASVLSTIEEKAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LIPB_CLAMS
Sequence: MVDIVVTGLSANSVPYIEALERQRALHADVVAGRAQDTVILLEHPSVYTAGRRTEPDDRPRDGTPVIDVDRGGRITWHGPGQLVGYPIVRLPEPLDVVAHVRRLEDALIALLAELGIASCRVDGRSGVWIRGTAPDGTPRDEKVAAIGVRVAERVTMHGFALNCSNALDAYDRIVPCGIRDAGVTSLSRVLGRTVTPADVVPLLRPHLVRALSNGSAMPATPALPSAAGARA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.