PharMolix/UniProtQA huggingface dataset:
Protein: RS5_RHORT
Sequence: MARTPNTDRRQRGGDDQRNRSPRSDERDEEFLDKLVHINRVAKVVKGGRRFAFAALVVVGDGKGRVGFGTGKAREVPEAIRKATDQAKRTMIKVPLREGRTLHHDTNGHFGAGWVTLRSAPAGTGIISGGPMRAVFETMGVQDVVGKCTGTTNPYNMIKATFDALVNSQAPRQVAARRGKKVGDIVARRDGAAAAGATE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SCS2_YEAST
Sequence: MSAVEISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQVQVIFLGLTEEPAADFKCRDKFLVITLPSPYDLNGKAVADVWSDLEAEFKQQAISKKIKVKYLISPDVHPAQNQNIQENKETVEPVVQDSEPKEVPAVVNEKEVPAEPETQPPVQVKKEEVPPVVQKTVPHENEKQTSNSTPAPQNQIKEAATVPAENESSSMGIFILVALLILVLGWFYR
What is the function of this protein?
Targets proteins containing a FFAT motif to endoplasmic reticulum membranes.  Regulates phospholipid biosynthesis by modulating the subcellular localization of the transcriptional repressor OPI1.
What are the official names of this protein?
Vesicle-associated membrane protein-associated protein SCS2, VAMP-associated protein SCS2, Choline sensitivity suppressor protein 2, VAP homolog 1.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Nucleus membrane; Single-pass type IV membrane protein.
Protein: RB11C_DICDI
Sequence: MPQEEEAEYLFKIVIIGDSAVGKSNLLNRFTRNEFTEKTKATIGVDFGTKSIEIDNKTITAQCWDTAGQERFRAVTSGYYRGAVGAMIVYDITSKISFKNVTRWLNELREMAEQDILIMMVGNKSDLEMSREVPTKEAQAFAESNKISFLETSALNSTNVNQSFERLLTDIYHLVSSKKPMVVDDTQNWLVPNQGKKLTPLSDPAPQLTANTTSTHQEKKSGCC
What are the official names of this protein?
Ras-related protein Rab-11C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: SYL_METTH
Sequence: MDIERKWRDRWRDAGIFQADPDDREKIFLTVAYPYPSGAMHIGHGRTYTVPDVYARFKRMQGYNVLFPMAWHVTGAPVIGIARRIQRKDPWTLKIYREVHRVPEDELERFSDPEYIVEYFSREYRSVMEDMGYSIDWRREFKTTDPTYSRFIQWQIRKLRDLGLVRKGAHPVKYCPECENPVGDHDLLEGEGVAINQLTLLKFKLGDSYLVAATFRPETIYGATNLWLNPDEDYVRVETGGEEWIISRAAVDNLSHQKLDLKVSGDVNPGDLIGMCVENPVTGQEHPILPASFVDPEYATGVVFSVPAHAPADFIALEDLRTDHELLERYGLEDVVADIEPVNVIAVDGYGEFPAAEVIEKFGVRNQEDPRLEDATGELYKIEHARGVMSSHIPVYGGMKVSEAREVIADELKDQGLADEMYEFAERPVICRCGGRCVVRVMEDQWFMKYSDDAWKDLAHRCLDGMKIIPEEVRANFEYYIDWLNDWACSRRIGLGTRLPWDERWIIEPLTDSTIYMAYYTIAHRLREMDAGEMDDEFFDAIFLDDSGTFEDLREEFRYWYPLDWRLSAKDLIGNHLTFHIFHHSAIFPESGWPRGAVVFGMGLLEGNKMSSSKGNVILLRDAIEKHGADVVRLFLMSSAEPWQDFDWRESEVIGTRRRIEWFREFGERVSGILDGRPVLSEVTPAEPESFIGRWMMGQLNQRIREATRALESFQTRKAVQEALYLLKKDVDHYLKRVEGRVDDEVKSVLANVLHAWIRLMAPFIPYTAEEMWERYGGEGFVAEAPWPDFSDDAESRDVQVAEEMVQNTVRDIQEIMKILGSTPERVHIYTSPKWKWDVLRVAAEVGKLDMGSIMGRVSAEGIHDNMKEVAEFVRRIIRDLGKSEVTVIDEYSVLMDASDYIESEVGARVVIHSKPDYDPENKAVNAVPLKPAIYLE
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRA_YERPN
Sequence: MPHTVATPPPLLQVRGISKQFSGVVVLKSIDFTLQPGQVHALLGGNGAGKSTLMKIIAGILPPDTGVIEMNGQPCFNLTPAKAHQLGIYLVPQEPMLFANLSVQENILFRLPKHQADKKKMAQLLKNLGCHLDLSVSAGSLEVADQQLVEIMRGLIRDSHILILDEPTASLTPAETHRLFSQIRMLLQQGVGVVFISHKLPEIRQLADWVSVMRDGGIALSGATADFSTEDMIQAMTPEAQKGALTDSQKLWLELPGNRRAQSHAQSQQPVIHVHDLSGEGFAHISFHVQAGEILGLAGVVGAGRTELAETLYGLRPASTGNVILEEVNITAMKTANRLAAGLVYLPEDRQASGLYLDAPLSWNVCALAHDRQGLWTQPAQEAAVLERYRRALNIKFSHLEQPVRTLSGGNQQKLLIAKCLEANPLLLIIDEPTRGVDVSARSDIYQLIRSIAEQQVAIIFISSDLEEVVQMADRVLVMHQGEINGALSGAAMNVDTIMHMAFGEHRSASEPQGGTASSAENKGASC
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Autoinducer 2 import ATP-binding protein LsrA, AI-2 import ATP-binding protein LsrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPH_STAAE
Sequence: MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPCKVIKAASEVQDTKKEIVAALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: NTCA_NOSS1
Sequence: MIVTQDKALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEEITVALLRENSVFGVLSLLTGNKSDRFYHAVAFTPVELLSAPIEQVEQALKENPELSMLMLRGLSSRILQTEMMIETLAHRDMGSRLVSFLLILCRDFGVPCADGITIDLKLSHQAIAEAIGSTRVTVTRLLGDLREKKMISIHKKKITVHKPVTLSRQFT
What is the function of this protein?
Has affinity for the xisA upstream region.  Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3'.
What are the official names of this protein?
Global nitrogen regulator, DNA-binding protein VF1, Nitrogen-responsive regulatory protein.
Protein: UCHL5_MOUSE
Sequence: MSSNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPESFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLETIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTPAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWITAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEEPMDTDQGSTVLSAIQSEVARNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKAKEKQNAKKAQETK
What is the function of this protein?
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains.  Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.  Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase isozyme L5, UCH-L5, Ubiquitin C-terminal hydrolase UCH37, Ubiquitin thioesterase L5.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus (By similarity).
Protein: SRE13_CAEEL
Sequence: MSFNISQENEFQTMYIKYFNKTYSIIEGSYNYYLFVFYIQIALIFIVLFYYLLNVYIDIKTCQFSTNTQKIHHAIYLPCVLGHVMCLIQKILLIKDSPAGDDMTNPVFYYISLFRAIFCFPGFYCLSAFVAERWFATYFLNDYEKNQRTWLVGLILWIIYSIAFISALDFHTAPSTVIHVTIFILLSCLAYLSNYLNFLLNRSYYYKSNRSDGGGYSLAQRFQISDNIRFSFFFNRLALSIAFFQISGPMCLLIDNLNISRSWKNLNTVVFDTILLLYAIVTPFVIYHHNPKYRTELQKIANSIRNIRVRTNKNQIMPMDSLDESFNSLRIQDTFGKTIVFNVTEQTSTYFEKLDRAWS
What are the official names of this protein?
Serpentine receptor class epsilon-13, Protein sre-13.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sre family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ILVC_STACT
Sequence: MTTVYYDETVKEDALKGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGNSFDKAKKDGFDVYPVDEAVKQADVVMVLLPDEIQGKVYEEEIAPNLEAGNALAFAHGFNIHFDVIQPPEDVDVFLVAPKGPGHLVRRTFTEGSSVPALFGVEQDASGNAFNLALSYAKGIGATKAGVIETTFKEETETDLFGEQAVLCGGVTRLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMETMRYSISNTAEYGDYVSGPRVITDDVKQNMKAVLEDIQNGKFANSFIEDNKNGFKEFYKLREEAQDHQIQEVGKELREMMPFVENKTIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DEOB_YERPE
Sequence: MKRTFIMVLDSFGIGASADAKKFGDEGADTLGHIAEACARGEANVGRSGPLTLPNLSRLGLGKAAEESTGTFPVGLDKNADIIGAYGYASELSSGKDTPSGHWEIAGVPVLFDWGYFSDVENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDRLYELCEIAREELTDGGYNIGRVIARPFIGDKPGHFQRTGNRHDLAVEPPAPTMLKKLVDEKGGEVVSIGKIADIYAQVGITQKVKATGLDALFDATIEEMKKAGDNTIVFTNFVDFDSSYGHRRDVAGYAAALELFDRRLPELMALIKEDDILILTADHGCDPTWPGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTVAAYFGLSPMDYGKNML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RELE2_METJA
Sequence: MKQWKYLLKKSFIKDLKELPKNIQEKIKKLVFEEIPNKNNPPEIPNVKKLKGADSYYRIRVGDYRIGFKYENGKIVFYRVLHRKQIYKRFP
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its cognate antitoxin is RelB2 (Potential).
What are the official names of this protein?
Putative toxin RelE2.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: RL11_HERAR
Sequence: MAKKIIGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGMPIPVVITAFADKSFTFVMKTPPATYLIKKAASITKGSAKANTDKVGKITRAQAEEIATTKRPDLTAADMDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: YCJF_ESCF3
Sequence: MTEPLKPRIDFDGPLEVDQSPKFKAQQTFDENQAQNFAPATLDEAPEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGAGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVTLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWLDDDKPRLGDFRRQLIGQLKETLQKAPTRREN
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS11_NATPD
Sequence: MADDTTWGIANVYASFNNTIITVTDMTGAETIVKSSGGTVVKQNRDEASPYAAMQMAEVVAEDVKDAGIDGVHVRVRGPGGNQQQNPGPGAQATIRALARAGLEIGRIEDVTPIPHDGTRGPKNAGF
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SLYX_XYLF2
Sequence: MHEKLLTLCDCAFEARLIELEMRVSFQEQALTEISEALAETRLIGARNAELMRHLLEELGKVRNTLYEHPIDEPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: FABI_ECO57
Sequence: MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: ADAS_DICDI
Sequence: MSGEKKEYPKEHIDLYQQIKWNGWGDTRKFLHQLKPSGTIAMTTPEVSSVPLPSLRGFIKKELTLPGEEDKPFVLDETPALQIENIHVDPPKQYPEFVRELKAFFLPDQLKDDKLARITHTFGKSLRDLIRVRIGQVKNAPDLIVLPHSHEEVERLVQLAHKYNVVIIPMGGGSNIVGAIEPVSNERFTVSIDMRRMNKVLWVDRREMTACIQVGIMGPELEKQLHKQGVSLGHDPDSFEFSTLGGWLATCSSGHQSDKYGDIEDMAVSFRTVTPTGTLELRNGARSGAGINYKHIILGSEGTLGIITEAVMKVHAVPQAVEYYGFLFPTFAHAVSALQQIRSSEVIPTMIRVYDPEETQLSFAWKPSKGAVSEFTSAMVKKYLHYIRSFDFKNVCLSIIGFEGPKKVVDFHRTSVFDILSKNAAFGLGSAPGKTWAEKRYDLPYIRDFLLDHNMWVDVAETTVSYANLQTLWKDAKQTFVKHFKDQGIPAWICAHISHTYTNGVCLYFIFASKQNENKDMAQYIEAKKLMTDIIFKYGGSLSHHHGVGYEHVPWMTRYATRGWINVYRSLKETIDPKDICNPRKLIPTIKEENNKEPFLFDVVNVKYPKL
What is the function of this protein?
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
What are the official names of this protein?
Alkyldihydroxyacetonephosphate synthase, Alkyl-DHAP synthase, Alkylglycerone-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SUT2_ORYSJ
Sequence: MPRRPSGGGGGAGPAAAAVRKVPLRKLLRAASVACGVQFGWALQLSLLTPYVQELGIPHAFASLVWLCGPLSGLLVQPLVGHLSDRIAPAASPLGRRRPFIAAGAASIAAAVLTVGFSADLGRIFGDSITPGSTRLGAIIVYLVGFWLLDVGNNATQGPCRAFLADLTENDPRRTRIANAYFSLFMALGNILGYATGAYSGWYKIFPFTVTPSCSISCANLKSAFLLDIIILVVTTCITVASVQEPQSFGSDEADHPSTEQEAFLWELFGSFRYFTLPVWMVLIVTALTWIGWFPFILFDTDWMGREIYRGSPDDPSITQSYHDGVRMGSFGLMLNSVLLGFTSIVLEKLCRKWGAGLVWGVSNILMALCFVAMLVITYVAKNMDYPPSGVPPTGIVIASLVVFTILGAPLAITYSIPYAMAASRVENLGLGQGLAMGILNLAIVIPQVIVSLGSGPWDQLFGGGNAPAFAVAAAASFIGGLVAILGLPRARIASRRRGHR
What is the function of this protein?
Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system).  May also transport other glucosides (By similarity).
What are the official names of this protein?
Sucrose transport protein SUT2, SUC4-like protein, Sucrose permease 2, Sucrose transporter 2, OsSUT2, Sucrose-proton symporter 2.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATA_ALKEH
Sequence: MHEKTVAEIAAALRAGEFSSREVTEAFLARIDALNPVTNAVITPTPEQALAAADAADQRIAAGEAGPLTGVPLVHKDIFCTQGVRTSCGSRMLDNFTAPYDATVVGKLADAGMVMLGKANMDEFAMGSSNETSYYGPVKNPWDLDAVPGGSSGGSAAAVAGRLAPAATGTDTGGSIRQPAALCGLSGLKPTYGRVSRYGMIAFASSLDQGGPMARTCEDLALLLGGMAGFDTRDSTSVDHVVPDYTETLNRSVKGLKIGVPKEFFGEGLDPEVRRVVEAAIEVYREEGAEIREISLPNTRHSVPVYYVIAPAEASSNLSRYDGVRYGYRCEDPSDLEDLYKRSRGEGFGEEVKRRILVGTYALSAGYYDAYYLKAQQVRRLIRDDFTRALQAVDVIMGPTSPTVAFNIGERTDDPVQMYLSDVYTLAVNLAGVPGLSIPAGFAQGRPVGLQIIGDYFDEARLLNVGHKYQQVTDWHRQVPQGFE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: YFG5_YEAST
Sequence: MRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPHMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLRVCCPS
What are the official names of this protein?
Uncharacterized protein YFL065C.
Protein: COX2_CYBSA
Sequence: MLLLINNLILNDVPTPWGLYFQDSSTPNQEGIIELHDNIMFYLVLILCTVSWLLFSIVKDSSKNPLPHKYLVHGQTIEIIWTILPAVVLLIIAFPSFILLYLCDEVISPAMTIKAIGLQWYWRYEYSDFINDSGETIEFESYVIPEDLLEDGQLRLLDTDTSVVCPVNTHIRFIVSAADVIHDFAIPSLGIKVVASPGRLNQVSALIQREGVYYGMCSETCGVAHSAMPMKIEVVSTKEFLTWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLMD_FERBD
Sequence: MAQFYSAKSNKTKHLSQKISLTPTALDHQGQAVAEHQGKVVFVPGLLPGESAQVQLVENKARFARAKVLKRTSDHPQRIAPPCPHFARCGGCQLQFAPTGLQRDLKQQALAQVVSKLSGLTPEQWAEPLLGPDWHYRRRARLGCRYDAGELVLGFRQEGSNRLTAIDHCPVLAEPLSELITPLQQLLAPLKLARHVGHLDLMLASEGPVVVVRLLRPLREEEREALAAFGQSRGVQMLIQGDALTDLSGQAVAPLHYDIGEGRPQPAFLPGDFFQVNGVVNQAMISQAIEWLQPQPGEKGLDLFCGGGNFTLALAGQSAEIIGVEGVPAMVERARARAAELGLEQLRFEYADLNGEAPKAQWLKDVDWVLLDPARAGAPGVMEWLAKLRPSRILYVACNPASLGRDGKVLAQQGYRLSRLGLVDMFPHTHHLESMALFEPGNNKHPK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: KAD_METRJ
Sequence: MRIILLGPPGAGKGTQSERIVQRFGIPQLSTGDMLRAAVAAGTPVGLEAKAVMESGGLVSDRIVVGIVADRIEEPDARRGFILDGFPRTVAQAEALGEMLASKGLSLSAVVELKVDENALVGRIEKRAAETLARGQAVRKDDTPEVFKQRLEAYRAQTAPLSAYYAQKGTLETVDGMQPIDKVTADLMAVLEPHEERVAS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L22H_OPHHA
Sequence: MKTLLLTLVVVTIVCLDLGYTTKCYVTPDATSQTCPDGENICYTKSWCDVFCSSRGKRIDLGCAATCPKVKPGVDIKCCSTDNCNPFTPWKRH
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin LNTX-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PR3D1_RAT
Sequence: MQLTLTLSRASGMQLFLLVSSLLLWEKVASKPTAIVSTDDLYHCLVEQSHNTFIMAADVYREFDINFAKRSWMKDRILPLCHTASIHTPENLEEVHEMKTEDFLNSIINVSVSWKEPLKHLVVCSDCSSGASVSMGKKAVDMKDKNLIILEGLQTLYNRTQAKVEENFENFDYPAWSGLKDLDSSDEEHHLFAICNLCRCVKRDIHKIDTYLKVLRCRVVFKNECGVSTF
What are the official names of this protein?
Prolactin-3D1, Chorionic somatomammotropin hormone 1, Placental lactogen I, PL-I.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_RHILW
Sequence: MRVYYDRDADLNLIKAKKVAVIGYGSQGRAHALNLKDSGAQNLVIALKAGSPTVKKAEADGFKVMTVAEAAGWADLMMMATPDELQADIYKADIAPNIRDGAAIAFAHGLNVHFGLIEPKASVDVVMIAPKGPGHTVRGEYQKGGGVPCLVAVHQNASGNALELALSYACGVGGGRSGIIETNFREECETDLFGEQVVLCGGLVELIRAGFETLTEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEWGEYVSGPRIITAETKAEMKRVLKDIQTGKFTSEWMQEYRSGAARFKGIRRNNDSHQIEEVGAKLRGMMPWIGKNKLVDKSVN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ADAT1_DROME
Sequence: MCDNKKPTVKEIAELCLKKFESLPKTGKPTANQWTILAGIVEFNRNTEACQLVSLGCGTKCIGESKLCPNGLILNDSHAEVLARRGFLRFLYQELKQDRIFHWNSTLSTYDMDEHVEFHFLSTQTPCGDACILEEEQPAARAKRQRLDEDSEMVYTGAKLISDLSDDPMLQTPGALRTKPGRGERTLSMSCSDKIARWNVIGVQGALLDVLISKPIYFSSLNFCCDDAQLESLERAIFKRFDCRTFKHTRFQPQRPQINIDPGIRFEFSQRSDWQPSPNGLIWSQVPEELRPYEISVNGKRQGVTKKKMKTSQAALAISKYKLFLTFLELVKFNPKLSEMFDQQLSDPERIAYASCKDLARDYQFAWREIKEKYFLQWTKKPHELLDFNPMSNK
What is the function of this protein?
Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
What are the official names of this protein?
tRNA-specific adenosine deaminase 1, dADAT1, tRNA-specific adenosine-37 deaminase.
What is the protein family that this protein belongs to?
Belongs to the ADAT1 family.
Protein: DEOB_THEP1
Sequence: MRVVLIVLDSVGIGEMPDAHLYGDEGSNTIVNTAKAVGGLHLPNMAKLGLGNLDDIPGVEPVKPAEGIYGKMMEKSPGKDTTTGHWEIAGVILKKPFDLFPNGFPKELIEEFERRTGRKVIGNKPASGTEIIKELGPIHEKTGALIVYTSADSVFQIAAKKEIVPVEELYRYCKIARELLDEMGYKVARVIARPFTGEWPNYVRTPERKDFSLEPEGKTLLDVLTENGIPVYGVGKIADIFAGRGVTENYKTKDNNDGIDKTISLMKEKNHDCLIFTNLVDFDTKYGHRNDPVSYARALEEFDVRLPEIIQNLKEDDVLFITADHGCDPTTPSTDHSREMVPLLGYGGRLKKDVYVGIRETFADLGQTIADIFGVPPLENGTSFKNLIWE
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_RHAHU
Sequence: MSRYRGPRFKKIRRLGTLPGLTSKRPKSGSDLKTQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLVRYVHIAGKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPRARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKQRSKALIQNYIASPPPEELPKHLTIDSFQYKGLVNQIIDSKWIGLKINELLVVEY
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.