PharMolix/UniProtQA huggingface dataset:
Protein: SYP_METS4
Sequence: MRLSRYFLPILRETPKEAEIVSHRLMLRAGMIRQEAAGIYAWLPLGLRVLNRVVEVIRAEQDRSGAIELLMPTIQSAELWRESGRYEAYGKEMLRIRDRHEREMLFGPTNEEMITAIFRSAVRSYKDLPKSLYHIQWKFRDEVRPRFGTMRSREFLMKDAYSFDLDEAGARHAYNKMFVAYLRTFARLGLKAIPMRAETGPIGGNLSHEFIILAQTGESEVYCDRAYLDFPIPPGSTDFDDVAALQATVDHWTSRYAATSEMHEPERFAAVPEEARMAARGIEVGHIFYFGTKYSEPMGARVTGPDGQERPVHMGSYGIGPSRLVAAIIEASHDEAGIVWPDAVAPFDVGLLNLKTGDIATDAACARIQEQLEAAGLSVLYDDRDERPGAKFATADLIGLPWQVIVGPKGLAEGQVELKRRATGERETVAPDALAARLRRGAAG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRFC_ORYSI
Sequence: MPPLHAVSPAAAAAPPRALSSAARVPQRPGCVPERPNILSSSTNFMSLRAGPMRFYSRPLILQNSDKRAVLRHATIEEIEAEKSVIEDQARERMEKAIETVQNNFNTVRTGRANPAMLDRIEVEYYGTPVNLKSIAQINTPDATSLLIQPYDKSSLKLIEKTIVAANLGVTPSNDGEVIRVTVPPLTSDRRKELAKTVAKLAEEGKVAIRNIRRDAIKAYDKLEKEKKLSEDNVKDLSADLQKVTDEYMKKIEAIQKQKEQELMKI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.
What are the official names of this protein?
Ribosome-recycling factor, chloroplastic, RRF, Protein OsL8, Ribosome-releasing factor, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENGB_CHLL3
Sequence: MKIINAAFIRSVSALQDLPDERVPEIVFAGRSNVGKSSLLNSLTGRKGLAKTSSTPGKTRLLNYFLINDDLYFVDIPGYGYAAVSHTEKDAWGRLLAGYVGGRQAIALVVLLLDSRHPAMESDREMMEFLAYHDRPYGIVLTKDDKLTQKERAKAKRVTASCALNAEFIVSYSSISGKGKKELLAHFDHYLSGESSGAGSDSAVTVT
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: UBID_CITK8
Sequence: MKYHDLRDFLTLLEQQGELKRITLAVDPHLEMTEIADRTLRAGGPALLFENPKGYAMPVLCNLFGTPRRVAMGMGQEDVTALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKVFSGDDVDLQRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDFQEWCAAHPGERFPIAVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCLSSDLEVPASAEIVLEGYIEPGEMAAEGPYGDHTGYYNEVDNFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTMKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPISGLGSKMGLDATNKWPGETQREWGRPIKKDPEVTARIDAIWDELAIFNDGKGA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NAO_PODAN
Sequence: MPIDFHLSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGILKGQISPAHGGTGGTLIESAILVEECYSVEPSAALTIFATGLGLTPINLAAGPQHAEFLAPFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWATNCAGWDFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVSGPHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKEDNRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAAKVFCSEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGNVGIRRRHLQQLMLKPTYDAWSSTYGSFP
What is the function of this protein?
Nitroalkane oxidase (NAO) catalyzes the oxidation of nitroalkanes to the corresponding aldehydes or ketones with the release of nitrite and the consumption of molecular oxygen to yield hydrogen peroxide (PubMed:20481475).  NAO is unusual, since it catalyzes substrate oxidation by removing a substrate proton to form a carbanion intermediate (PubMed:20481475).  Prefers longer nitroalkanes, with 1-nitrohexane having the highest activity (PubMed:20481475).
What are the official names of this protein?
Nitroalkane oxidase, NAO.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: LUTA1_BACAA
Sequence: MKVTLFVTCLVDMFETNVGKATVEVLERLGCEIEFPEAQVCCGQPAYNSGHVEAAKEAMKHMIETFEDAEYIVTPSGSCATMFHEYPHVFKDDPKWAKRAQKVADKTYEFTQFIVDVLKVTDVGASLPGIATIHKSCHMTRMLGVTEAPGILLSNVKGLTVRELPNVQNCCGFGGTFSVKMTPISEQMVDEKVDSAMETGADYLIGADCGCLLNIGGRIERLGKEIKVMHIAEVLNSRS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 1.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: RS2_MYXXD
Sequence: MAAAGGITMRQLLEAGVHFGHQTKRWNPKMKPFIFGARNGIYIIDLQKTVVMARSAFRFVADITARGGSVLFVGTKKQAQDVVREEASRAGQFFVTSRWLGGTLTNFKTIKQGIDRLKTLEKMAEDGTFERLPKKEVAQLEREREKLEKNLGGVKEMSKLPRCVFVIDPKKEHIAIHEAGRLGIPVIGLVDTNCDPDGIDFVIPGNDDAIRSIKLFTSKIAEACLEGAARYRASGAAERDEQEEREGRDDRGDRRDDRRGPRRGDRRDDRRDRGGDRGGDRRGPLVEMKGAAPVASAEPAAEAAPEGEAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NTPPA_LACP3
Sequence: MIILASHSPRRQELLKRIVPDFESHPASINERALPVLDPPAYVQSLATAKGQSLVPSYPGATIIAADTMVAFQGKLLGKPHDRAEAKQMITALGGQTHQVYTGLWVRLDNGSVRQQVVTTDVTFWPLSEADVESYLAEDAYQDKAGAYGIQDAGALLVKSIQGDFYNVMGLPSSTLYRMLLAEPQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RORB_MOUSE
Sequence: MCENQPKTKADGTAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNGLSNLNTETGGTYANGHVIDLPKSEGYYSIDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMSEIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPDIVNTLFPPLYKELFNPDCAAVCK
What is the function of this protein?
Isoform 1 is critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina.  Regulates the expression of PTF1A synergistically with FOXN4.
What are the official names of this protein?
Nuclear receptor ROR-beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, Retinoid-related orphan receptor-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm.
Protein: EFTU_CALBD
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLALKGKAQFMAYDQIDKAPEERERGITINTAHVEYETDARHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVNVPYIVVFLNKVDMVDDPELIELVEMEVRELLSKYGYPGDEVPIVKGSALKALESTSQDPNAPEYQCILELMDAVDKYIPTPQRDIDKPFLMPIEDVFSITGRGTVVTGRVERGTLKTGEEVEIVGFAPEPRKTVVTGIEMFRKVLDEAVAGDNVGCLLRGIQKNEVERGQVLAKPGTIKPHTKFKAQVYVLTKEEGGRHTPFFNGYRPQFYFRTTDVTGTITLPEGVEMCMPGDNVEMTVELISPIAIESGLRFAIREGGRTVGAGSVTTIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_ECOL6
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAON_HUMAN
Sequence: MGAALGTGTRLAPWPGRACGALPRWTPTAPAQGCHSKPGPARPVPLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEDGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEPKDKEAFVRSLVYTPDYDSFTLDSYTWPKEAMNVQTV
What is the function of this protein?
Catalyzes the oxidative decarboxylation of (S)-malate to pyruvate using NADP(+) as a cofactor (PubMed:7818469).  Can also reverse the decarboxylation reaction, but only with significantly lower efficiency (PubMed:7818469).
What are the official names of this protein?
NADP-dependent malic enzyme, mitochondrial, NADP-ME, Malic enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FTSIH_CHLAT
Sequence: MKPYEPKSWVTRVFLVWWLTALSCFFISGRLIYLQLLKGKWLKEKALKQQTVTLKTFQPRRNICDRNGIPLAIDTLAYDVFAHPLYFSISIEEVANKLSPILCIDSLSIQKLLKPTSTGICLASQLPENTGKLIASLRLDGIDLIKHPKRYYPYKEIVGNVIGYVDTSHQGQAGIELSCQESLQLNSPTLTSSIDGRGVLISHQIPKELFIQDNLSLQLTLDLELQKIAYKALKQGLENCKGKRGTVLILDPKTGGILTLVALPSYDPNIYYDFPIERFKPWPVTDLYEPGSTFKPLNIAIALETKAISPEDSFYDEGCIRVGDSIITNNDYNSYKPLPCLPNTYNKIVKLLANSSNVGMVHILERIAPEIYHSWLSKLDLGHAASPLETDLPWASESSLKDINEFVCYEIEPAAASFGQGLAMTPIKLAQLYASLANGGILVKPYLVTGLANAAEDTQKAKGIDLPSYNIRKKNLGNHLSWHKAEPSYLFLKRSGIRVTDLLRHIKAEGRFALPFRKNLLQLFTQDAHRTTELQLEPKAHQPQLLRPTRHAVYATNQSKRVFSHETTKLLLDMLEDVIWNGTGSSCFVEGYRIGGKTGTSQKHTQEGGYSKTKIITSFAAIFPTEDPQYVILTVIDEPNIPLSFGSNTAAPIVKSIIESLIDIKKMKPTIPIIKVKKD
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase FtsI homolog.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Single-pass membrane protein.
Protein: EFTS_STRP8
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHLGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLVAP_HUMAN
Sequence: MGLAMEHGGSYARAGGSSRGCWYYLRYFFLFVSLIQFLIILGLVLFMVYGNVHVSTESNLQATERRAEGLYSQLLGLTASQSNLTKELNFTTRAKDAIMQMWLNARRDLDRINASFRQCQGDRVIYTNNQRYMAAIILSEKQCRDQFKDMNKSCDALLFMLNQKVKTLEVEIAKEKTICTKDKESVLLNKRVAEEQLVECVKTRELQHQERQLAKEQLQKVQALCLPLDKDKFEMDLRNLWRDSIIPRSLDNLGYNLYHPLGSELASIRRACDHMPSLMSSKVEELARSLRADIERVARENSDLQRQKLEAQQGLRASQEAKQKVEKEAQAREAKLQAECSRQTQLALEEKAVLRKERDNLAKELEEKKREAEQLRMELAIRNSALDTCIKTKSQPMMPVSRPMGPVPNPQPIDPASLEEFKRKILESQRPPAGIPVAPSSG
What is the function of this protein?
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae.  It is also required for the formation of stomata of caveolae and transendothelial channels.  Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs.  Plays a specific role in embryonic development.
What are the official names of this protein?
Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein, Plasmalemma vesicle protein 1, PV-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Membrane, caveola; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.
Protein: RPOA_DIOEL
Sequence: MVREEIAESTRTLQWKCVESRVDSKRLYYGRFILSPLMKGQADTIGISMRRALLGEIEGTCITRAKSEKVPHEYSTVVGIEESVHEILFNLKEIVLRSNLYEIRDASICVRGPRYVTAQDIISPPYVEIVDTTQYIANLTEPIDLCIELEIKRDRGYRMKPITNSQDGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALYEASRNLIDLFVPFLHAEEEDINFEENKNKFTLPPLTFQDRLSNLKKNKKGIPLKYIFIDQLELPSRTYNCLKRSNIHTLLDLLSKGQENLIKMEYFHIEDVKQILDTLQKHFAVDLPKVLI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YCAD_SHIF8
Sequence: MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLSSFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITAMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFSAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHHL_ECOLI
Sequence: MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMHGMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLAWQKKFKVKK
What are the official names of this protein?
Uncharacterized protein YhhL.
Protein: PTWB_STRCO
Sequence: MASKAEKIVAGLGGIDNIDEIEGCITRLRTEVNDPALVNEAALKAAGAHGVVKMGTAIQVVIGTDADPIAAEIEDMM
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylglucosamine (GlcNAc) transport.
What are the official names of this protein?
PTS system N-acetylglucosamine-specific EIIB component, PTS system GlcNAc-specific EIIB component, N-acetylglucosamine-specific phosphotransferase enzyme IIB component, GlcNAc-specific phosphotransferase enzyme IIB component.
Protein: HBSAG_HBVH3
Sequence: MGAPLSTARRGMGQNLSVPNPLGFFPDHQLDPLFRANSSSPDWDFNTNKDNWPMANKVGVGGFGPGFTPPHGGLLGWSPQAQGILTTSPPDPPPASTNRRSGRKPTPVSPPLRDTHPQAMQWNSTQFHQALLDPRVRGLYLPAGGSSSETQNPVPTIASLTSSIFSKTGDPAMNMENITSGLLGPLLVLQAVCFLLTKILTIPQSLDSWWTSLNFLGVPPGCPGQNSQSPISNHLPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLLPGSTTTSTGPCKTCTTLAQGTSMFPSCCCTKPSDGNCTCIPIPSSWAFGKYLWEWASARFSWLSLLVQFVQWCVGLSPTVWLLVIWMIWYWGPNLCSILSPFIPLLPIFCYLWASI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: RS21_PLUXY
Sequence: MQNDAGEFVDLYCPRKCSASNRLIHAKDHASVQLVIADVDPATGRAADSSKMYVVCGAIRRMGESDDCIVRLTKKDGILVKNY
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: GRPE_LAWIP
Sequence: MTDHTPLQPKHEITDQADQDTSAEMLVEEEDKKEIGPNYITEEEAQEIRLRALAEMENFKKRLQKDHDEQIRYAIDNLLTDMLPVLDSLDLAIQYGSNDDACKDILMGVSMTRKLFLDTLKQYGVTVLGEINEPFNPELHEAIAHEEREDIPEGHVSTLHQRGYQLYERLLRPAKVSVSSNKNNSNTNK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_PARPJ
Sequence: MFARLPLYLRLVRMDKPIGSLLLLWPTLNALWIASDGHPTWPLLVIFTVGTVLMRSAGCAINDYADRDFDRYVKRTENRPITSGKIKAWEAVALAAALSLLAFLLILPLNTLTKELSVAALFVAGSYPFTKRFFAIPQAYLGIAFGFGIPMAFAAIQGHVPLLAWVMLLANVFWSVAYDTEYAMVDRDDDIKIGIRTSALTFGRFDVAAIMICYAATLGIYVGIGVLLGFGVLYWLGWAAAAGCAIYHYTLIRNRERMACFAAFRHNNWLGGALFVGIAAHYAAGSF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AQN1_PIG
Sequence: AQNKGPHKCGGVLRNYSGRISTYEGPKTDCIWTILAKPGSRVFVAIPYLNLACGKEYVEVQDGLPGAGNYGKLCSGIGLTYQSSSNALSIKYSRTAGHSASSFDIYYYGDS
What is the function of this protein?
AQN proteins mediate the binding of boar spermatozoa to component(s) of the egg's zona pellucida by a carbohydrate-binding mechanism.  AQN proteins are secretory components of the male accessory glands being coated to the sperm surface at the time of ejaculation.  They possess as well heparin-, serine-protease-inhibitor-binding capability.
What are the official names of this protein?
Carbohydrate-binding protein AQN-1, Spermadhesin AQN-1, Zona pellucida-binding protein AQN-1.
What is the protein family that this protein belongs to?
Belongs to the spermadhesin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAB2_MOUSE
Sequence: MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDESGISGLRNHMTSLNLDLQSQNVYHHGREGSRVNGSRTLTHSVSDGQLHGGQSNNELFQQEPQTAPAQVPQGFNVFGMPSTSGASNSTPHLGFHLGSKGTSNLSQQTPRFNPIMVTLAPNIQTGRSTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPSGTARQTQQHSGWVSQFNPMNPQQAYQPSQPGPWTTYPASNPLPHTSTQQPNQQGHQTSHVYMPISSPTTPQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNSSSKLRSSGPRTASTSSLVNSQTLNRNQPTVYIAASPPNTDEMISRSQPKVYISANATAGDEQGMRNQPTLFISTNSGPSAASRNMSGQVSMGPAFIHHHPPKSRVLGGNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPALAHVDRISEARKLSMGSDDAAYTQALLVHQKARMERLQRELEMQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSTIKAPKTQDAEDEEGAQWNCTACTFLNHPALIRCEQCEMPRHF
What is the function of this protein?
Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF) (By similarity).  Acts as an adapter linking MAP3K7/TAK1 and TRAF6 to 'Lys-63'-linked polyubiquitin chains (By similarity).  The RanBP2-type zinc finger (NZF) specifically recognizes Lys-63'-linked polyubiquitin chains unanchored or anchored to the substrate proteins such as RIPK1/RIP1: this acts as a scaffold to organize a large signaling complex to promote autophosphorylation of MAP3K7/TAK1, and subsequent activation of I-kappa-B-kinase (IKK) core complex by MAP3K7/TAK1 (PubMed:19927120).  Regulates the IL1-mediated translocation of NCOR1 out of the nucleus (PubMed:12150997).  Involved in heart development (By similarity).
What are the official names of this protein?
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, TAK1-binding protein 2, TAB-2, TGF-beta-activated kinase 1-binding protein 2.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cytoplasm, cytosol. Nucleus. Note=Following IL1 stimulation, translocation occurs from the membrane to cytosol. Interaction with TRIM38 promotes translocation from cytosol to endosome and lysosome.
Protein: CCA_LISMF
Sequence: MNDVFLKALPVLQKLTTAGFEAYFVGGSVRDYLLNRTISDVDIATSAFPEEVKEIFQTSYDTGIAHGTVTVRENNEFYEVTTFRTEGTYEDFRRPSEVTFIRSLEEDLKRRDFTMNAIAMDEHFALQDPFSGQLAIQNKEIKAVGKASERFHEDALRMMRAVRFLSQLDFELDKETEKALESQIELLQHTSVERITVEWLKMMKGKAAKRAIELLLKVKMETYLPGLKDEKSALSEFASWDWEKRTTEESIWLGLVVAVKPNNVNAFLKAWKLPNKTIQLVNKAYQDALKMKETWLKDELYHAGKAVFSLVNELNVIRGKENNQHKVSQAYEALPIHSKKDLAITGADLLKWSGESAGPWVKETLDKVECGVLSNEINNEKIQIKRWLGYHEE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.