PharMolix/UniProtQA huggingface dataset:
Protein: IPIL2_MOUSE
Sequence: MSVRYTLNLRVFWPLVTGLCTALVCLYHALRSSEDARAESPDGADSGFPLLKVAILLLLGYILLRCRHAIRQRLLPGSSRPRGHANFSARSLQEPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVQAGRARGSPGLITGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPQVALEPRSLGTEPSLTPAFRSCFVCALKAPPSPSGASTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGSLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRDLGARGLDPMAATHWGRILSSYVLKTAVLEVLLNEGSPTPSWDEAHLSECLEKLVKFLRDCLLRRRDLFHCVLGPTGAAAEVGPLPKVLREAAPVDLLAPFDPHSRELAAARLLSTWRRLPQLLRVYGGPRYLARCPAPRSQRIQGSPEDEP
What are the official names of this protein?
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the ITPRIP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS3A_ARTOC
Sequence: MAVGKNKRLSKGKKGLKKRTVDPFTRKDEYLVKAPTTFQVRDVGKTLVNRTTGLKNANDYLKGRVFEVSLADLQKDEAHSFRKVKLRVDEVQGKNCLTNFHGLDFTSDKLRSLVRKWQTLIEANVTVKTTDDYLVRLFAIAFTKRRPNQIKKTTYAQSSQIRAIRKKMTEIIQRQASSCTLTQLTKLVPEVIGREIEKSTQGIYPLQNVHIRKVKLLKSPKFDLGALLALHGEASTDDKGQKVEREFKEKVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIF1_YEAST
Sequence: MDAQLEWASSLVPKRQLQQQQQQQEQQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHETMVNGSKRRL
What is the function of this protein?
Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y450_BIFLD
Sequence: MSGHSKWATTKHKKAAIDAKRGKLFAKLIKNIEIAARLGGGDPDGNPSLYDAIYKAKKASMPADNIARAVKRGAGAEDGAANYEDIVYEGYAPAGVGLIIECLTDNRNRAAAEVRSTLTKGNGSLATSGSVSFNFERKGQIVVPSEGVDFDKLFETAAEAGAEDVTDDGEVFTVVTGPSDLFTVRKALQEAGFDYDSADQVMQPKNEVELSLEDARKVSKLIDNLDDLDDVQNIYSNWTASDEVMAQLDEE
What are the official names of this protein?
Probable transcriptional regulatory protein BLD_0450.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_BACTN
Sequence: MMIEVLKSKIHCARVTEANLNYMGSITIDEDLLDAANMIPGEKVYIADNNNGERFETYIIKGERGSGKICLNGAAARKVQPDDIVIIMSYALMDFEEAKSFKPTVIFPDPATNSVVK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7A_MOUSE
Sequence: MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L7a, Surfeit locus protein 3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF3_NEMVE
Sequence: MSLPRHTLAIQALYRRVLKLHRKLPLEIKALGDQYAKDEFRRHKKASQEQAVRFMQEWKIYADTIEQQVNSQQLNVLGKDLKDEHIESLTEEQLGQLYSLQEAALKPDSSEPRDI
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYP_FUSNN
Sequence: MRFSKAYIKTLKETPKEAEIASHKLMLRAGMIKKLASGIYAYLPLGYRTIKKIENIVREEMDRAGALELLMPVVQPAELWQESGRWDVMGPEMLRLKDRHERDFVLSPTQEEMITAIIRSDISSYKSLPINLYHIQTKFRDERRPRFGLMRGREFTMKDAYSFHTSQESLDEEFLNMRDTYTRIFTRCGLKFRPVDADSGNIGGSGSQEFQVLAESGEDEIIYSDGSEYAANIEKAVSELINPPKEELKEVELVHTPDCPTIESLAKYLDVPLERTVKALTYKDMGTDEIYMVLIRGDFEVNEVKLKNILNAVEVEMATDEEIEKIGLKKGYIGPYKLPAKIKIVADLSVPEVSNHIVGSHQKDYHYKNVNYDRDYTADIVTDIRKVRVGDNCITGGKLHSARGIECGQIFKLGDKYSKAMNATYLDEKGKTQFMLMGCYGIGVTRTMAASIEQNNDENGIIWPVSIAPYIVDVIPANIKNEVQVSLAEKIYNELQEEKIDVMLDDRDEKPGFKFKDADLIGFPFKVVVGKRADEGIVELKIRRTGETLEVSQNEVIAKIKELMRIY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FZD1_XENLA
Sequence: MKHSHLLQRCSAQLCTRGSSLILSLLLSVCLSVEGQYNGEKGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELKFFLCSIYAPVCTVLEQALPPCRSLCDRARQGCEALMNKFGFQWPESLRCEKFPINGAGELCVGQNTTESGTPTPAVPETWTSNSRTYYRDKFMCPRALKVPAYVNYHFLGEKDCGAPCEVGKVHGLMYFAPEELNFARIWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTMVAIAYIAGFLLEDKVVCNERFAEDGYKTVAQGTKKEGCTFLFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAVGQVDGDTLSGVCFVGINNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWEKSWISQSCKTYAIPCPSTGHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
What is the function of this protein?
Receptor for Wnt proteins.  Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10969734).  The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10969734).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
What are the official names of this protein?
Frizzled-1, Fz-1, Xfz1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA_ACIBS
Sequence: MLILTRRVGETLMIGDQVSVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQHERAMHEHLQHLDQDYQVSYEDDNYAQKNFNR
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQHA_ECO55
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_CUSJA
Sequence: MRINPPTYGSEISSIEKKNRGCIVQIIGPVLDVAFPPGKMPNIYNALVVKGRDTEQMNVTCEVQQLLGNNRVRAVAMNDTDGLMRGMEVIDTGTPITVPVGGSTLGRIFNVLGEPVDNFGPVDTNTTSTIHRSAPAFIQLDTKLSIFETGIKVVDFLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINENNITESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSMMLQPRIVGEEHYETAQKVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFNLILSGELDSLPEQAFYLVGNIDEATEKAMNLKT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, plastid, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: ENGB_YERPY
Sequence: MTIRNYNYHMTHFVISAPDIRHLPRDEGIEVAFAGRSNAGKSSALNTLTNQKGLARTSKTPGRTQLINLFEVVDGVRLVDLPGYGYAEVPEEMKLKWQRALGEYLQKRNCLKGLVVLMDIRHPLKDLDQQMITWAVAVGTPVLLLLTKADKLASGARKAQLNLVREAIIPFMGDIQVEAFSSLKKIGVDKLREKLDTWFSEIPPEVMAEEFDGEGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: MUG45_SCHPO
Sequence: MKNLANIKLYWNENDFLIADMLLILKLSPRSSSDCLLDLRDRKWELVCCKELNIGNERNPLNVPLFELPVNSLELQNSVSNDMFKHVYSQNVELNHKTQVDFTEQLIPKKSLNKLNGTLRETMSRMPSFESISLSETSNALDDSCFNDDWITIESEFSPPIDRGMTLEAMDSQNDTLFTSKQLNNGPNFPVEKATFFLESNMGLSQRAAATSTTPVCNISSVTSAINSVGEISNASHSSSTSELPCTYGNTSSIFQVKNEMSNIKSAISEGYIAHDQQSKKVSVQNIKKEFLIPFEFSLEGGFLNYNKTFSNLYKVLSETEKTRDSKVWFTFRLVLKTKPLYASESEFYETKLNFFTFPLECAINFHIDCSCFDDWRLFSLKESSSVAVPIPKIKKESGRSMFQSLLFQFNHCIPFRLSWINYKQSQLNIILTETTIRPRICAAYQKLEYNILVLLNEKPSSGSQLILSASPTCTIENIYIENTRLHFSKSQTPEQTVISFIDVQCVKVTEATKTLELSVILSERLVYETALKLPVIKYVKGDNRFCFKQLLEYYDIYLKFKLLADWRLLTNPVLQIQEISDYCHFKLLKKVNRNLQIKTNYPTQEFHLLRPTIKILQISKHEYFLHFSSSYIFNDARERDVYGVKLSKNMWISWAYVDNCEANFFCKDGTYFFRTTSRKQILLLEIGILIKPERYNLFKYRVYLPQFLPPTDSRTLVEFQTIVYTNSTLLFDGSFYFSQNGGFDFEPRQNYTYFDFKSEFIILQNSYSIYGPAKNIIKLLLELIEVILNVNVSTTAMCLLTLLIGIYLILQVVFIYTN
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 45 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLMM_MYCSJ
Sequence: MARLFGTDGVRGVANRDLTAELALALGSAAARRLSTAGHARRRVAVVGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLPTPAVAYLTSAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDATEDRIAELVQQGPGERPVGAGIGRVVDAPDALDRYLRHVGKAVTTRLDALTVVVDCAHGAASAAAPLAYRAAGANVLTINADPNGLNINDGCGSTHMETLQAAVVSYGADLGLAHDGDADRCLAVDANGRVIDGDAIMVVLALAMRESGELASDTLVATVMSNLGLHLAMRDAGIEVRTTSVGDRYVLEELRAGSYSLGGEQSGHIVMPSMGTTGDGILTGLRLMSRMAQTRKSLAALAEPMHTLPQVLINVQVADKTTVAQAPSVQSAVAEAEAALGDTGRILLRPSGTEQVVRVMVEAADEDTARQLAVRVAESVSEQR
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TPIS_LACP7
Sequence: MRRKIIAGNWKMNKTPSETVKLIEELKPLVKNDDVDVVFCVPAISLTTAIEAAKGSNISIGAENMFYEESGAYTGEIAPNMLTDIGVKYVIIGHSERREYFAESDITVNKKVLKALEHGITPIICCGESLTQREQGITIDWIRQQIKIAFLNVTAEQAATTVIAYEPIWAIGTGKVATTEQAQEVCAAIRVCIGELYGETTAEAIRIQYGGSVTAASAPELFTQSDIDGGLVGGASLKPDFGQIVNYK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_MYCBP
Sequence: MVHHGQMHAQPGVGLRPDTPVASGQLPSTSIRSRRSGISKAQRETWERLWPELGLLALPQSPRGTPVDTRAWFGRDAPVVLEIGSGSGTSTLAMAKAEPHVDVIAVDVYRRGLAQLLCAIDKVGSDGINIRLILGNAVDVLQHLIAPDSLCGVRVFFPDPWPKARHHKRRLLQPATMALIADRLVPSGVLHAATDHPGYAEHIAAAGDAEPRLVRVDPDTELLPISVVRPATKYERKAQLGGGAVIELLWKKHGCSERDLKIR
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: COQ6_SCHPO
Sequence: MSSLVLRGVSRVEMPTISPTLGIYTRKFASQKILQRQFDVVIVGSGPVGLALAAGLQSNPVTQSLKVGLLDIQDTMKLKDWKFETYSNRCSSLTNHTRMFFDKIGAWDFARKDRIQPFQHILASDGLTNSSIHLDQKPGSEPMAFMSENVNLQYALLNSIIDKMNNNIKKPNLEFLMPCTITKLSKGENIYRTHIHTTTHGELTTKLLIGADGRNSIVRKYANISMPGWNYLTHAVVGTLKIDPLKGPAVAFQRFLPTGPLAYLPLPDNNATFVWSTRPHIASKLLRLPEETFVKFLNASFRLDYPDLSYLYQMDFSEPSKVNEQLDWRLQVKRNSNMQVPPVITEIVSGSRAAFPLRLAHVDEYVKEGIALCGDAAHNTHPLAGQGLNTGIQDVESLISALSFAIKHGQDIGSVFSLQPYFRDRYFKNHVYLGVVDKFHKLYAMENPVVTSVRTLGLSLFDRSASLKNFILSTVANGI
What is the function of this protein?
FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis.  Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid.  The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
What are the official names of this protein?
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the UbiH/COQ6 family.
Protein: LIPA_COXBN
Sequence: MTTYDPSQKSLGKEKLSRIPVKIEATHTPLRKPDWIRIRLSTDSKVSQLKKLLRENHLVTVCEEASCPNLNECFGHGTATFMIMGDKCTRRCSFCDVGHGRPDPLDPEEPVNLANTVSIMSLRYVVITSVDRDDLRDGGAQHYAQCINAVREKNPGIKVEVLVPDFRGRMEKALDQLAQGLPDVFNHNIETAPRLYKQARPGADYPWSLALLQTFKKRFPGIPTKSGMMLGLGETREEVETVMRDLRQHEVDRLTLGQYLQPTRYHMPVDRYVTPQEFQELGELAKKLGFSNVASGPLVRSSYHADLQAQGERVS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_BACMK
Sequence: MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDRENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKNEVINIPIAHGEGNYYCDEATLKQLEENNQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_STRZP
Sequence: MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLDIGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRALEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHSPNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIGESGVQDRILSQIEEFLDD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: DXS_SALDC
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKDRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVMGLISTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPGYSKIFGDWLCETAAKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQVIHDVAIQKLPVMFAIDRAGIVGADGQTHQGAFDLSYLRCIPDMVIMTPSDENECRQMLFTGYHYNDGPTAVRYPRGNAQGVALTPLEKLPIGKGLVKRHGEKLAILNFGTLMPEAAKVAEALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: T23O_XANC8
Sequence: MPVDKNLRDLEPGIHTDLEGRLTYGGYLRLDQLLSAQQPLSEPAHHDEMLFIIQHQTSELWLKLLAHELRAAIVHLQRDEVWQCRKVLARSKQVLRQLTEQWSVLETLTPSEYMGFRDVLGPSSGFQSLQYRYIEFLLGNKNPQMLQVFAYDPAGQARLREVLEAPSLYEEFLRYLARFGHAIPQQYQARDWTAAHVADDTLRPVFERIYENTDRYWREYSLCEDLVDVETQFQLWRFRHMRTVMRVIGFKRGTGGSSGVGFLQQALALTFFPELFDVRTSVGVDNRPPQGSADAGKR
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RNH_RICM5
Sequence: MGSKVVIYTDGACAGNPGPGGWGALLQFNDTSKEVFGYELDTTNNRMEITAALEALRMLKKSCNIEIYTDSKYLQQGITAWIHNWIKNNWCKSNNEPVKNADLWQKLYAELSKHTIIWKWVKGHANNSGNIAADKLAVQGRETAIEILKCRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_PSESM
Sequence: MRDRLLAAEKVKAIDWRDDALYLLDQRVLPFEEVWHRYTTAAGVAEAIRTMVVRGAPAIGISAAYGAVLGARARIAEGGDWYPALEEDMQLLADSRPTAVNLFWALNRIRDRLMRVKNGDNPLAALEAEAVAIHLSDREANLTMAQLGADLIRKHQGNLQTVLTHCNTGALATGGFGTALGVIRAAHLEGMIERVYADETRPWLQGSRLTAWELANEGIPVTLNADSAAAHLMRTKGITWVIVGADRITANGDVANKIGTYQLAVAAMHHGVRFMVVAPSSTIDMEMASGDDIIIEERDGRELLEVGGQRVGADVEAFNPVFDVTPADLIDAIVTEKGIVERPDTARMAQLMSRKHLH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: MFP2_ARATH
Sequence: MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQASSRL
What is the function of this protein?
Involved in peroxisomal fatty acid beta-oxidation during seed germination.  Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18) (PubMed:10521521, PubMed:16507084, PubMed:20463021).  Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is involved in the peroxisomal beta-oxidation pathway for the biosynthesis of benzoic acid (BA).  Required for the accumulation in seeds of substituted hydroxybenzoylated choline esters, which are BA-containing secondary metabolites (PubMed:24254312).  Fatty acid beta-oxidation pathway in peroxisomes regulates gene silencing, histone acetylation and DNA methylation (PubMed:31064880).
What are the official names of this protein?
Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2, AtMPF2.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Glyoxysome. Peroxisome.