PharMolix/UniProtQA huggingface dataset:
Protein: RIX1_CANGA
Sequence: MNKAIPVSVLADQLAESNGFQFHNILYHLKSSDYVDEKLLKSELSVLVVKIQKLLNSNSNYSIWKGCHAAVVICTYNPLVLMAYGGKLLDIVYQKLEIKVLQRSTNSLDAQGKQVLNSLVNAISVLMNLMRNKTGLSREFLVPKIKAIIPTLITLSQYEPELVLPILRSLIFKHTTTFKPFNAKFKVILTQFLTEGFDTLNEHTQKLVCDCYAYLHMVKTQTYQQQDEHSSHHKTFQDENWMNGMNAVLAEFKPLIELCGEILDFSQDEELTKLIGKMVPLAAESTSIFRSLTMDMNKSTTLYDIPKRIDVLSKMLMSFISVPTTYTIRIPLDKLNVTCSALLSITSKHIPIKRELRRDIELNATINDVFTKIQFAGIRLYSTMVSKFGNVCFSYLSDIFYALSLFIPFKEKSLNIDFEKCFALKREFLVVFDLVSKIIANVGHQLTDIDFLLQLIEIGLDLTEERSLIQNVFQQTNAKKEQELSKTKNKNKKDNKRGSLADLYVSGSQFTLACDLKTFDTLNKFFISIIANQKLATAQMTKLSRYAIFTAQTYKQNLGEVPTTFVELLRTLVIQPGNERVTILPMAVNIIKESSDDVFDILSHPRLPMSILHSIEKSTFDNGEDDEDDNPDLHANEKQQEYNDQPVERSEQKVVDFVLEEPVAVDVKTKETVQFKDGITTSEDQVDTKRPRDEEFIIEKSSSAKKFRTENQPETIPIGVSDETVYQETEKVTVNVDTSSNDNEDDEDDSDFEIPAIELSDDDDEDE
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits.  Regulates pre-60S association of the critical remodeling factor MDN1.
What are the official names of this protein?
Pre-rRNA-processing protein RIX1.
What is the protein family that this protein belongs to?
Belongs to the RIX1/PELP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGOD_SALPK
Sequence: MKITHITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHEFADYLIGKDPARINDLWQVMYRAGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIEKLRGIGFDTFKLNGCEEMGVIDNSRAVDAAVNTVAQIREAFGSEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSRFEFKRVLDAGGLGILQPDLSHAGGITECYKIAGMAEAYDVALAPHCPLGPIALAACLHIDFVSRNAVFQEQSMGIHYNKGAELLDFVKNKEDFSMDGGFFKPLTKPGLGVDIDEARVIELSKSAPDWSNPLWRHADGSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: ATPF1_CERS1
Sequence: MKKLSILAVLAASPAMAATGPFLSLSNTNFIVTLAFLIFMGILLYAKVPGRVLGMLDKRSVQIRTELEEARALREEARTILASYDRKQKEVQEQAARIVASARDEAQAAAEQAKADLRASIARRLAAAEDQIASAEAGAVRAIREQAVSVAVAAAADLLSRQMTPAAASASIDESIKEVEARFH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CARB_STRT2
Sequence: MPKRSDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYSVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMELSKAGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFATEIGYPVIVRPAFTLGGTGGGMCANEEELREIAENGLKLSPVTQCLIERSIAGFKEIEYEVMRDAEDNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALKIEGGCNVQLALDPHSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMINPVTGTTYAMFEPALDYVVAKIPRFPFDKFEHGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVYHNEMSELAEVTDDALVEKVVKAQDDRLFYISEAIRRGYTIEELSELTKIDIFFLDKLLHIFELEQELAAHVGDVDVLKEAKRNGFSDRKIADLWNQTANQVRATRLENNIVPVYKMVDTCAAEFESSTPYFYSTYEWENESIKSDKESVIVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIELEQPKGVVVQFGGQTAINLAEPLSKAGVKILGTQVADLDRAEDRDLFEQALKDLDIPQPPGQTATNEEEAVEAARKIGFPVLVRPSYVLGGRAMEIVENEDDLRSYMRTAVKASPDHPVLVDSYIIGRECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSKKIQETIADYTKRLAIGLNCIGMMNIQFVIKDETVYVIEVNPRASRTVPFLSKVTDIPMAQVATNLILGKSLAEQGYKDGLYPESNHVHVKAPVFSFTKLAQVDSLLGPEMKSTGEVMGTDVTLEKALYKAFEASYLHLPTFGNVIFTIHDDTKEEALDLARRFDAIGYGIYATEGTAKFLNEHGVHATLVNKLGENDDNDIPALVRTGKAQAIINTVGNKRTYDEDGAAIRSSAIEAGIPLFTALDTADAMVRVLESRSFTTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MNME_ACICJ
Sequence: MSLAPSDVIFAPASGVGGAISLLRLSGAGVARVIGALAGSLPAPRRASLRSFRDGRRGIIDRGLLLWFPGPASVTGEDYAEFHLHGGRAVRAAITAALLDLGARPAEPGEFSRRAFLNSRLDLLEAEGIADLIDAETEAQRQLALDLAGGAMSRAVAAWREALIGLMAQLAALIDFADEDLPAEVEAAMLASMARLRDEIVAAIGAGLAAERLREGVEIVVLGAPNAGKSTLVNALAGEEVAIVSDIPGTTRDAIGVRLDLGGVPVRLVDTAGLRRSDDAIEAEGVRRAEAHARRADLLILCGAAPDFVVPDAPADVPALRIATKADLGGAVPAAMLAVSARTGAGLADLLAALRARVEALVERGAGPALPRPRQIACLRDVAAALDRALAIDVPELRAEEMQAAAVALARLTGTIGVEDVLDQVFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR9A_DROME
Sequence: MSDKVKGKKQEEKDQSLRVQILVYRCMGIDLWSPTMANDRPWLTFVTMGPLFLFMVPMFLAAHEYITQVSLLSDTLGSTFASMLTLVKFLLFCYHRKEFVGLIYHIRAILAKEIEVWPDAREIIEVENQSDQMLSLTYTRCFGLAGIFAALKPFVGIILSSIRGDEIHLELPHNGVYPYDLQVVMFYVPTYLWNVMASYSAVTMALCVDSLLFFFTYNVCAIFKIAKHRMIHLPAVGGKEELEGLVQVLLLHQKGLQIADHIADKYRPLIFLQFFLSALQICFIGFQVADLFPNPQSLYFIAFVGSLLIALFIYSKCGENIKSASLDFGNGLYETNWTDFSPPTKRALLIAAMRAQRPCQMKGYFFEASMATFSTIVRSAVSYIMMLRSFNA
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
What are the official names of this protein?
Odorant receptor 9a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or1a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_ANGMA
Sequence: MANLRKTHPLLKIANDALVDLPTPSNISAWWNFGSLLGLCLISQIITGLFLAMHYTSDISTAFSSVAHICRDVNYGWLIRNLHANGASFFFICLYLHIARGLYYGSYLYKETWNIGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGDSLVQWIWGGFSVDNATLTRFFAFHFLFPFVVAGATMIHLLFLHETGSNNPVGLNSDADKIPFHPYFSYKDLLGFIIMLTALTMLALFYPNLLGDPDNFTPANPMVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLSSILVLMVVPILHTSKQRGLTFRPASQLLFWILVADMLVLTWIGGMPVEHPYIIIGQVASVLYFSLFLVLNPLVGWLENKMMNW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL25_FRATW
Sequence: MANFVLKAEKREDLGTGASRRLRRAGKIPAVIYGGEKEAVSVLLDHDKVLHSTEDKAFFSSEITLDIDGKQEKVIIKALQRHPYKVKLIHADFMRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: PLSX_STAES
Sequence: MVKIAVDMMGGDDAPGIVLDAVKKAVEDFKDLEIILFGDESQYNLSHERIEFRHCTEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTTDGKGFVFLDVGANADAKAEHLLQYAQLGNIYAQKIRGIQNPSVSLLNIGTEAAKGNSLTKKAYDLFEKNQSFNFTGNIEAKTLMDGNVDVVVTDGYTGNMVLKNLEGTAKSIGKMLKETIMSSFKNKLAGAVLKKDLETFAKKMDYSEYGGSVLLGLDGTVVKAHGSSNAKAFYSAIKQAKIAGEENIVQIMKDTVGE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DHSL_THEVB
Sequence: MAVPAVEFPWEEQPMSAFATPITPAPIPDNISLTELIDKYFTAYNSARLREICQLLSQRVFKPEVTVGLSLSGAMTPTGLGISALAPLVRAGFVDYIISTGANLYHDIHYALGMDLYAAHPFVDDVQLRKESKIRIYDIIFDYDVLLETDAFLRQVLRSETFQRRMGTAEFHYHLGHYVRELEVQRGQPHSCLLATAYECGVPIYTSSPGDSSIGMNVAAIALEGSKLIIDPAIDVNETAAIAYFAREAAGGKGKSAALIIGGGSPKNFLLQTQPQIHEVLGLEERGHDYFIQITDARPDTGGLSGAVPSEAVSWGKVDPQGLRDTVVCYTDSTIALPILTAYCLNRCQPRPLKRLYDRRGEMVERLQQLYLQAQLQHKVKELPTEAPVATYPCGTPIRRP
What are the official names of this protein?
Deoxyhypusine synthase-like protein.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: MUTS2_CLOB6
Sequence: MKDKSIKVLEFNKIQEILKNYTCTKAGKDIIEDLKPYDSVYEVREHLEETKEAFKLLITKGAPPFEGVYDIRNGIYLAEKGSALLPGQLLKIAAVLRCARRFREYINHKEQEESYRVLENICEGIFSLPKIEEEIFNAIEGEDEIADRASSTLYNIRRSLKEKNYSVRDKINSLVRSYSSYLQENIYTVRRDRYVLPVKAEHKGAVPGLVHDQSSTGATLFIEPMSLVNLNNEIKELMLKEKAEIERILTVLSAKINANITGVKTDANIVWELDFIFAKAKFASEYNCTCPTINDEGIVDIIEGRHPLIDRREVVPISVKLGEEFTSLMITGPNTGGKTVTLKTVGLIHLMAMSGLMIPARENSVISYFNNVFADIGDEQSIEQSLSTFSSHMKNIVEIMDKADENSLVLFDELGAGTDPTEGAALAISILENLRKRGAKIIATTHYSELKAYALRKEGVENASVEFDVETLRPTYRLLIGIPGKSNAFEISKRLGLPDYIIDFARENISNENIRFEELIQNLQEKSIKAQEDARLAENLKLERDKEKKKYEEKLEGLQKVRDNALIDARREAKNIIKEAKEEADKILKDIRQLERMGYSSDARRKLEEERKKLKDKLDSIEEKEIKTVHKGEALKNVKEGDEVLLASINQKVIVLSKPDNKGDVLVQAGIMKITANIKDLRAAKGSNFNSNSSKTKKSKKLNLNLRKVESSVDLRGMDAEEAIYTVDKYLDEAYLGGLGEVTIVHGKGTGVLRKTIMDMLKGHPHVKRYRLGEYGEGGTGVTVVEIK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RF3_PSEAE
Sequence: MTTQAAEVAKRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISITTSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMEVCRLRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYKDFKGVYHLADDRIIVYVPGHGHERIETKVIEKLDSDEARAHLGDLYDNFVEELELVQGACHEFDKDAFLKGEMTPVFFGTALGNFGVDQVLDCIVDWAPQPLSRATHERSVEPTEEKFSGFVFKIQANMDPKHRDRIAFMRICSGKYEKGMKMRHVRLGKDVKIADALTFFSSEREQLEEAYAGDIIGLHNHGTIQIGDTFSEGENFGFTGIPHFAPELFRRVRLKDPLKSKQLRQGLQELAEEGATQVFFPERNNDIILGAVGVLQFDVVASRLKEEYKVECAYEAINVWSARWIECDDEKKLKEFKDKAFENLSVDGGGHLTYLAPTRVNLSLMEERWPDIRFRATREHH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARHG4_MOUSE
Sequence: MDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDYEAPRAGAREADDSGPEAQSCKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKREDMFSEEQLRTIFGNIEDIYRCQKAFVKALEQKFNTERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQRMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKNVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIHSGELTRVTQPQARSQQRMFFLFDRQLIYCKKDLLRRDVLYYKGRLDMDDLEVVDVEDGKDRDLHVSVKNAFRLYCGTTGDSHLLCARKPEQKQRWLKAFAREREQVRLDQETGFSITELQRKQAMLNASKQQATGKPKAVGRPGYLTRHKHPSLPASRPQQQVLVLAEPRRKPSNFWHSISRLAPFRK
What is the function of this protein?
Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases.  Binding of APC may activate RAC1 GEF activity.  The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion (By similarity).  Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells.  Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor, Asef.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalized with APC in the synapse of olfactory glomerulus.
Protein: NDHK_SYNP6
Sequence: MVLTNPAEIRNPAAPPEITQGLSENVILTTLDDLYNWARLSSLWPLMYGTACCFIEFAALIGSRFDFDRFGLVPRCSPRQADLLITAGTVTMKMAPALVRLYEQMPEPKYVIAMGACTITGGMFSADSTTTVRGVDKLLPVDVYIPGCPPRPEAIIDAIVKLRKKVANDSIQERGKLLQTNRYYSTTHQMKPTAPLLTGEYLRSAARQAGPLPAAAGAAVAPQLPVTEKEGRDRA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISX_HUMAN
Sequence: MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST
What is the function of this protein?
Transcription factor that regulates gene expression in intestine.  May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine (By similarity).
What are the official names of this protein?
Intestine-specific homeobox, RAX-like homeobox.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECC_BUCAP
Sequence: MFFVYRSNQIDILFTKICKIIKKKPLLNIFEREIIIHDNEILFQNLNTFIANHTGIAADFKLIYPNVFIWKLFKQVFSDIQLNNIFSRSTITWKIMKIIEENDFCKFVQKKDKIMKKFEFSFLMSHLYQQYILYRPNWINMWEKNKKNTLKIEKKDEWQAKLWIKIILYTEKLQQSKWHFSNLFKKFKTLKKIEHIKFPKRIFIIYSISLNPKYMEIFKKISTYTDIYFLSINACEKKIFHISFAKNYVVQKNNLLMNLSEKYEKFYFLFFKKFKKIKYNNFFQKNNSNNLLNIVKNDFLNFKEKENLLKKNSFLLKDNSISINICCDKKHEIEVLYNKLLSFFNEDSKLKPSDIVITSFSLNTYIIYINSIFKSKNKKEKIPFYISKKHSDKIEKILFIFNKILNLPNIRCNNEEILDLIEIQDIRDKFDISEEEINILYEWIEKANIRWGLHENEKQKNNLIFIKKNQNTWFYGIKKLLISHAINEEEEVWNNVLSCTSINTSRTELIGKLINFIKVLDQWRDKLFFSKKIKSWRPLFLCFIKDFFYKNEKIRDSIDIINKTWTKMIDDATLSNYEKKIPISILKKKFSHIMNNFSEKKFLPGVINFCHPSLVCYIPFKIKCIIGAEYQEIPKKKLSSFNLIDKYPLTSDLHICKENYIFLQNFISTQETLYISYVGHSLKNNNKVRSSILIDQLLNHITSNFYVSEHHDYKNNKKEIFEHICKKHKKENLYEKKQVNKINLNTLQKTKKINQEIYNKIFSIKNRIISTSTQISLKSLISFWKNPIRYFFNYTLNIKLKIAKRNIITEPFSINLFDDFKISNIIFKKILNNESIKDEFKKIILSGILPYGHFGSILLKEKKKEIENIVKAIYKYRISSPKKENFDIKIEKYNINGCLDEIQNTGLLRWKLGTINYRDRISLWLEHLIYCILGGTGESKIIGYKKNFFSFYPLSSHLAYNYLFTYIEGYMKGMKNPLLLIKSGSNWFDKVYDKKNDCIKKNDDIKRKAYKILYHTWMGNEYITGEKEDLYIQQIISELNVKKICKISQKWFTPILKHQKK
What is the function of this protein?
A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair.  Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity.  Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction.  Cuts ssDNA a few nucleotides 3' to the Chi site.  The properties and activities of the enzyme are changed at Chi.  The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair.  Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination.  In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
What are the official names of this protein?
RecBCD enzyme subunit RecC, Exonuclease V subunit RecC, ExoV subunit RecC, Helicase/nuclease RecBCD subunit RecC.
What is the protein family that this protein belongs to?
Belongs to the RecC family.
Protein: PDXS_HALH5
Sequence: MVDTGTDRVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPADIRAAGGVARMADPTIVEEVMNAVSIPVMAKCRIGHIVEARVLEALGVDYIDESEVLTPADEVYHLNKRDFTVPFVCGARDLGEAARRIGEGASMIRTKGEPGTGNIVEAVRHMRMMQAQIRKVSNMSTDELMTEAKNIGAPYELLLSIKETGELPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSETPEKFARAIVEATTHYEDYDLIAKLSKGLGTAMKGIEISTLDASERMQERGWEKGS
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MNME_BORPD
Sequence: MASSTHVPIAAIATAPGRGGIGVVRISGPDLSALARRLFGRELTPRHAHYLPFTAETGEHLDEGIALYFRAPQSYTGEDVLELQGHGGPAVLRRILERCLQAGADLGVRLAEPGEFTRRAFLNDRMDLAQAEAVADLIDASSVAAARGAMASLSGEFSARVNALSDRIVHLRMLVEATLDFPEEEIDFLEKYQARPTLQALAADLATLIAQARQGVILREGLHVVLAGKPNVGKSSLLNALAGDDIAIVTPIAGTTRDKVVQEIHIDGVPLHIVDTAGLRDTDDTVESIGIARTWKEIERADVILHLQDATQPADELDAQIVARLPARTPLLTVFNKVDLLDQPFQAQAGQLGISAREGAGLDELRARLLALAGWNPGAESPWLARERHVHALQRAAEHLEAATEHAAQDDRVLDLFAEELRLAHDSLSSITGKFTSDDLLGEIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CX001_HUMAN
Sequence: MYSRLFYLKSSYIIYFEPLFSNAIINILSFINSLASPLTIFCFALSAQALSTIFYFRIFIFIFHSWILLFHFYFTCSFKTYEHQHSKMVPAYRMQSPRALPRTYLYVWPYK
What are the official names of this protein?
Putative transmembrane protein CXorf1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MRAY_GEOMG
Sequence: MLYHLLYPLASDFRIFNVFKYLTFRTIYAVITALLVSFILGPWVIRKLEALQARQVIRTDGPESHLKKSGTPTMGGILILASIVIPTLLWADLTNRYVWTTLFVIVGYGLIGFTDDYKKVVEKNPKGLSPRQKMAGQLLIAGMAVCFLVFVVNMSTELAFPFFKRLHPDLSWFYIPFAMLVIVGASNAVNLTDGLDGLAIGPVAINAATYLLFTYIAGNAKLSSYLQTPYVPGAGELAVLCGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGTLAVITKQEILLVIVGGVFVVEALSVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNTP_XYLFT
Sequence: MSPITTLLIGIAMSTDAFAAAIGKGAAIGKPRLRDALYVAVIFGVIETATPIAGWLLGQVASHYIATFDHWIAFGLLGGLGIHMIVNGLKNNGNTCKDNADTHNRNSRWLTLAATALATSIDAAAIGISMAFLDIHIGIVAAVIGLCTFTMVIFGVMLGRVLGTFVGNRAEIVGGIILIIVGSTILYEHLSNTG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_PSEF5
Sequence: MLLLLAEYLQQFYKGFAVFQYLTLRGILGVLTALSLALCLGPWMIRTLQNRQIGQSVRNDGPQSHLSKSGTPTMGGALILSAIGISTLLWADLRNHYVWVVLLVTLAFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLGAAIFLYMTAQSPVETTLLIPMLKDVSIPLGIGFVVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGAGELIVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTIAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMH_LACP3
Sequence: MNIKIIGVGKLKEKYFRDGIAEYLKRMDKFAKVKIVEVADEKAPENLSEAEMADVKAKEGDRILGKIKDKEWVIALAIEGKQRPSEVFAKEIADLGTYGHSDITFVIGGSLGLSPAVMKRANDTLSFGKLTMPHQLMRLVLMEQIYRAFMINIGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSA_GLOVI
Sequence: MSILIDNVSKNFGDFQAVADIRLEIQPGNLVALLGPSGCGKSTLLRLIAGLELPDSGQIWLEGQDATRQRLQERNIGFVFQHYALFKHLTVAQNIAFGLEVRKTPKAQIKARVEELLELVQLAGYGGRYPAQLSGGQRQRVALARALAVEPRVLLLDEPFGALDARVRKDLRAWLRRLHDEVHVTTIFVTHDPEEALEVSDTIVVMNKGRVEQVGSPVEIYDHPESAFVMSFLGQVNTLPNSPELFPQLSEAVREVLVRPHDLSLSVQAGGPALAARVERLMYLGWQVQAELVLEAGQPLIVQLSREQADRLQLRPDQPVYVQVRNPKIFPAVAADKQLAEAAA
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.