PharMolix/UniProtQA huggingface dataset:
Protein: GCS2_BURTA
Sequence: MALETFVNSEPFTFGVELEIQIVNTHNYDLTKAASDLMRLIKDAKFPGNITPEITESMIELSTGICRTHDQALGELHAIRDTLVNAADQLNVGLCGGGTHAFQQWSERQIFDAPRFQYISELYGYLAKQFTVFGQHVHIGCPDADSALFLLHSMSRFIPHFIALSASSPYVQNVDTGFHSARLNSVFAFPLSGRAPFVLTWSGFEEYFTKMVNTGVVNSMKDFYWDIRPKPGYGTIEVRVMDTPLSVDRAAAIACYIQTLARYLLIDRPLKLSEDDYLVYTFNRFEACRFGLEGTCVNPQTGERRTIAEDILDTLDRIAPHAAALGSRAALDEIGALAKARVNDASWLRTIFKQEKSLNETVRQQCLRWRE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: HIS6_DELAS
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNAQGADELTFLDITATSDGRDLILPIIESVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAAIANPEVINAASDKYGAQCIVVAIDAKRRTAEDEQRMGADGRAAGPGWDVYSHGGRKNTGLDAVQWAAEMARRGAGEILLTSMDRDGTKSGFDLKLTRAVSDAVPVPVIASGGVGSLDDLADGVTLGGADAVLAASIFHYGEFTVGQAKQRMAERGVPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHL2_ORYSJ
Sequence: MRSPRGGAAAQPSGRRGDTTAAAAGDLVTTQVSLGGFDAGVAAGDLADFLEHEVGLVWRCRVKTSWTPPDSYPDFALPTAPASASAAAAPPRYDRVPPHAFVHFARPEGARRAADLAGETRLILRGKPLRVASAPDSSLRVSRRSSIAPFRFPDVRLEVGALPSPGAFLAAWRGPDAGLDLSVDPFDGCCRLVFTRDTAFTFPGFREVAAIRCDVKLEFPVRDVLEVRLYRLDCSLLLRLAAAPLVHYRTADDDFHEPVPFDLLDDDDPWIRTTDITPSGAIGRCGVYRISFSARFWPKMDRALDYMRERRVAIVDCGGGWGPRRGLTVRDELEFGEPMQDVFFCLQHAEGLKFPLLFMVNALVHKGIINQHQLTPEFFSLLGRSEENVNVAALRDFWGDKFPVFDACGRLKKALNRVARNPKLLCSKVGDDHAEVRRLVITPTRAYCLPPEVERSNRVLRHYHEVADRFLRVTFMDEGMQVLNNNVLNSFTAPIVKDLMSNFFQQKTTVYKRVRMLLTEGFHMCGRKYSFLAFSSNQLRDKSAWFFAEDRKTTVEAIRKWMGRFTSKNVAKHAARMGQCFSSTYATVTMRPDEVDESFDDVVHNEYIFSDGIGKITPDLALEVAERLQLTDNPPSAYQIRFAGFKGVIAVWQGHGDGTRLFLRPSMRKFESNHLVLEVVSWTKFQPGFLNRQIIILLSSLNVPDSIFWQMQETMLSNLNNILSDRDVAFEVLTTSCADDGNTAALMLSAGFEPRTEPHLKAMLLAIRSAQLQDLLEKARIFVPKGRWLMGCLDELGVLEQGQCFIRATVPSLNSYFVKHGSRFSSTDKNTEVILGTVVIAKNPCLHPGDVRILEAVDVPELHHLVDCLVFPQKGERPHANEASGSDLDGDLYFVTWDEKLIPPGKKSWNPMDYSPPEAKQLPRQVSQHDIIDFFLKNMISENLGRICNAHVVHADLSEYGAMDEKCIHLAELAATAVDFPKTGKLAIMPPHLKPKVYPDFMGKEDGQSYKSEKILGRLYRSIQEASNGDVVSQEVCTPNDLPYDIDLEVPGASDFLASAWQCKCSYDAQLSALLSQYRVRTEAELVTGHITFLVKNSSKKQGDIKDRLKTAYSALRKEFKSTFESIASDQCEIGDDEKNLLYEMKASAWYQVTYHPKWVEKSRGILGPDGEEIPASLSFAWIPVDYLARIKLRCHGKVRVEGQKPVERLAAYISERI
What is the function of this protein?
Involved in the RNA silencing pathway.  Probably required for the generation of small interfering RNAs (siRNAs).  Regulates shoot apical meristem (SAM) initiation and maintenance and leaf polarization through the trans-acting siRNAS (ta-siRNAs) pathway which probably modulates the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes.
What are the official names of this protein?
Probable RNA-dependent RNA polymerase SHL2, Protein SHOOTLESS 2.
What is the protein family that this protein belongs to?
Belongs to the RdRP family.
Protein: ZNG1_SCHPO
Sequence: MDFEIENESEIPQLVDVEEVNTQPHSETLSVPTVSSNNDIDSFEQQSDFLLVDHDSTLDPVPVTILTGFLGAGKTSLLRSILENRNGKRVAVLMNEVGDSGDLERSLMEDVGGEELYEEWVALSNGCMCCTVKDNGIKALEKIMRQKGRFDNIVIETTGIANPGPLAQTFWLDDALKSDVKLDGIVTVIDCKNIDNILKDESDIGFIQISHADCLILNKTDLISSEALSVVRQTILKINCLAKIIETTYGRLDDISEILDLDAYGNENTSNLEWSIQRSNDSNINCSTCLDVDCQHLHSLDTHSLDISTHTFKLPPLMSKEVFQQFLQWVRHTLWSCLEEGEDEEFMIYRSKGIFNKDDGSWYIFQGVREVFEIMPLSEKPRAFLEKDIHPEIILIGRNLHRISPFVVGNQ
What is the function of this protein?
Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them.  Catalyzes zinc insertion into the active site of methionine aminopeptidase map1, which function to cleave the initiator methionine from polypeptides during or after protein translation.  Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of map1.  After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of zng1 to the zinc binding site in the peptidase domain of map1 in a process requiring GTP hydrolysis.  GTP/GDP exchange is required for release of active map1.
What are the official names of this protein?
Zinc-regulated GTPase metalloprotein activator 1.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Protein: REPI_ECOLX
Sequence: MATHKPINILEAFAAAPPPLDYVLPNMVAGTVGALVSPGGAGKSMLALQLAAQIAGGPDLLEVGELPTGPVIYLPAEDPPTAIHHRLHALGAH
What is the function of this protein?
This protein is involved in regulating the plasmid copy-number.  Increasing the level of this protein results in a higher plasmid copy-number.
What are the official names of this protein?
Regulatory protein RepI.
Protein: PYRG_ALISL
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATIQVIPHITNAIKERVISGAAGHDIALVEVGGTVGDIESLPFMEAIRQLAVELGREHTMFMHLTLVPYLVAAGELKTKPTQHSVKELLSIGIQPDILVCRSDRVIPANERKKIALFCNVQEKAVISMKDVDSIYKIPQLIRAQGTDDLVCQRFGITAPAADLSEWEQVIYEEANPTGEVTIGMVGKYIELPDAYKSVNEALKHAGLKNRLSVTIKYIDSQDVESKGTEILEGLDAILVPGGFGDRGIEGKILAAQYARENAVPYLGICLGMQVALIDYARNVANMEGAHSSEFSKDTKFPVVGLITEWIDGDGNVEERTEKSDLGGTMRLGSQLCHLAKGSKARELYGNATVEERHRHRYEVNNNLLPQLEKAGLKISGLSADKKLVEIIEIPNHPWFVAAQFHPEFTSTPRDGHPLFEGFVKAAGENARGEFEK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ISPE_PSEA6
Sequence: MDQTIDWWPSPAKLNLFLHINGRYPNGYHQLQSLFQLLDKGDELAFTVTPHAEITLLTPIDGVANEDNLIVKAARLLQTHTGCSEGCDIQLRKVLPMGGGIGGGSSNAATTLIALNYLWKCNLSLTELAELGLALGADVPVFVMGNTAFAQGVGEQLTPVNIAQKHYLVVFPECHVSTAEVFNAPDLPRNTPLISWQEYDFDQTHNDCQQLVCNRFENVANTLRWLLEYAPSRMTGTGACLFAVFTSNQEAENVLANLPSGCSGFVSKGVDVSPVHDKLAHLGSIS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RS13_CAMC5
Sequence: MARIAGVDLPNKKRIEYGLTYIYGIGLYKSRQILDAAGISYDKRVFELSEDEAAAIRKEIQEHHIVEGDLRKQVAMDIKALMDLGSYRGLRHRKGLPVRGQKTKTNARTRKGRRKTVGAATK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ECSIT_HUMAN
Sequence: MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPEPRQRPTKALVPFEDLFGQAPGGERDKASFLQTVQKFAEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQLLNIFPKEVFRPRNIIQRIFVHYPRQQECGIAVLEQMENHGVMPNKETEFLLIQIFGRKSYPMLKLVRLKLWFPRFMNVNPFPVPRDLPQDPVELAMFGLRHMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDNLQRQQQGQS
What is the function of this protein?
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
What are the official names of this protein?
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Protein SITPEC.
What is the protein family that this protein belongs to?
Belongs to the ECSIT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: RRAGA_HUMAN
Sequence: MPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECACFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAQIIEADEVLLFERATFLVISHYQCKEQRDVHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKHSLLMR
What is the function of this protein?
(Microbial infection) May alternatively act as a cellular target for adenovirus E3-14. 7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
What are the official names of this protein?
Ras-related GTP-binding protein A, Rag A, RagA, Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1.
What is the protein family that this protein belongs to?
Belongs to the GTR/RAG GTP-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state (PubMed:8995684, PubMed:9394008). Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane (PubMed:8995684).
Protein: GATA_SALTO
Sequence: MTDLTSFSAAELAGLVARGESSAVEVTQAHLDRISAVDDRVHAFLHVDTEGALDAARDVDSRRAAGEPLGPLAGVPVAVKDVLTTKGVPTTAGSKILADWRPPYDSTIVRRLRAAGTVMLGKTNMDEFAMGSSTEYSAFGPTHNPWDLSRIPGGSGGGSSAALAAYETPLSIGSDTGGSIRQPGAVTGTVGVKPTYGGTSRYGLVAFSSSLDTPGPCARTVLDAALLHEVIGGHDPLDSTSIPAPVPDVVAAARLGASGDLTGVRLGVVREFAGEGAEPGVLAAFHAAVETLTKLGAEVVEVSCPHFQYALPAYYLIAPSECSSNLARFDGVRFGLRVGDDGIRSLEEVMSATREAGFGPEVKRRVMLGTYALSSGYYDAYYGQAQKVRTLISRDFTTAFEQVDALISPTTPFVAFPVGARTADPYQMYLADLFTIPSNLYGGPGISVPCGLADGLPVGLQVMAPTMADDRMYRVAAALESVVGPFTPPAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: WSCD1_ARTBC
Sequence: MAGILSVVHIIIIFIVRFKSSTDSLITVVVSASFQRANIYKFSLLAKLAHGAALIPRADADTWTYLGCYTDQVGARTLGQVGYTLGGPGNMTVANCQNGCASQGYSLAGVEYSSECWCDNQLRNGGGPAPDGEAMCSMPCNGNPEQKCGGPGRLNLYQNTAIKPTDTMTTSAPSTETGSPTTTSVPEPTQGLPDGWQYSGCYQDNVNGGRVMFKMLPDSSTLTIESCVAMCVKLGYTVAGAEYSKQCFCDNYLRNAAPQAIESECSMTCSGNTQQKCGGPSRLSVYSKGNLTVLPIPVPQTGGLPGGWKYQGCLQDNVNMKRTFPYQIVDKTNNTATNCLSRCSKFGFGAGGMTYSEECFCGDFEDIAAAGAKLVPEAMCSQTCSGNATAICGAGNLITYYRWMDEPLQKWNRPTGINAGRYDFLIGGVLVPLITTVGINGKITFQEKSGTGDPNTTGAYEFDPYYEKDFSKAWREMHVKTDIFCAGGLVLPDKVGRQLTVGGWSGISTEGVRLYWPDGSPGKPGVNDWHESPDDLRLQNGRWYPTAMTMSNGSILVVGGEEGSNGAPVPTLEILPRVGPVLFMDWLKRTDPNNLYPYLTPLPGGNILAAYYNEARILDERTFDTVKTLPNIPGAVNNDAGGRTYPLEGTMVLLPQKAPYTEPLGVLICGGSTPYGGDALDNCVSIQPEVPNAEWVIERMPSKRVLTCMAGLPDGTFLILNGARKGVAGFGLAEDPNLGAVLYDPSKPVNQRMSIMANTTIARMYHSEAILMADGRVLVSGSDPQDPRFPQERRVEVFLPPYILSGARRPTFTIANKDWAYGGKYKIKITSGNQSRIKISLMGMVSSTHGNSFGSRTIFPAFSCSFGTCTITAPPDSHTCPPGWFMLFVLDGPTPSVASFVRIGGDPGRLGDWPATGGFPLPGV
What are the official names of this protein?
WSC domain-containing protein ARB_07867.
What are the subcellular locations of this protein?
Secreted.
Protein: MSPB_MYCS2
Sequence: MTAFKRVLIAMISALLAGTTGMFVSAGAAHAGLDNELSLVDGQDRTLTVQQWDTFLNGVFPLDRNRLTREWFHSGRAKYIVAGPGADEFEGTLELGYQIGFPWSLGVGINFSYTTPNILIDDGDITAPPFGLNSVITPNLFPGVSISADLGNGPGIQEVATFSVDVSGPAGGVAVSNAHGTVTGAAGGVLLRPFARLIASTGDSVTTYGEPWNMN
What is the function of this protein?
A backup porin induced when MspA, the major porin, is deleted.  Probably forms a water-filled channel which favors the permeation of cations.  There are about 2400 porins in wild-type, 800 in an mspA deletion and 150 in a double mspA-mspC deletion.  A triple mspA-mspC-mspD deletion mutant has low but detectable channel activity.  Different conductance values with maxima at 2. 3 and 4. 6 nanosiemens might be caused by a simultaneous reconstitution of MspB channels into the membrane or by the existence of different MspB conformations.
What are the official names of this protein?
Porin MspB.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial porin (TC 1.B.24) family.
What are the subcellular locations of this protein?
Cell outer membrane. Secreted, cell wall.
Protein: PKSD_BACSU
Sequence: MNEPLVFMFSGQGSQYYHMGKELFKENTVFRQSMLEMDAIAARRIGTSIVEEIYHPGKRVSDPFDSILFSHPAIFMIEYSLYKVLEDRGIYPDYVLGSSLGEFAAAAVSGVSDAEDMLDCILEQAIIIQNSCDKGKMLAILDKPQLLNDHPQLFGNSELISINYDSHFVISGEEDHIRKIMEDLKEKQILCQLLPVSYAFHSSLIDPAESAYAEFLRSKSFQKPSIPIVSSLTGSCLHVMDENFFWNAVRKPMMFREAIRYLESQHTCKFIDLGPSGTLAAFVKQLIPGDSADRCCSIITPFHQELKNLNTVEYFRTPERKFTR
What is the function of this protein?
Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
What are the official names of this protein?
Polyketide biosynthesis acyltransferase homolog PksD, AT, Transacylase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_SALTI
Sequence: MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLLALARGGIESIVATQKAALEN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: YIFN_ECOLI
Sequence: MAINFSPKVGEILECNFGNYPVSQNGPFSTTYYDGRIPPEMIKNRLVVVLNGKINGNACIVVPLSTTRDQDKLKRGMHVEIASNVINDLQFFDQQIRWAKADLVQQVSRNRLNRARTYRGYLNQCLPHELVADIQRAVIKSINAISLIN
What are the official names of this protein?
Putative uncharacterized protein YifN.
Protein: YEAH_SALPC
Sequence: MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQGGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIAELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYDPGQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQAKFDNFAMQHIRDQEDIYPVFRELFQKQSANQSA
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RCF1_SCLS1
Sequence: MPSNTPLPSSFDGDTDFYEENRWQKLTRRLKEEPLIPLGKSTHTLTLSPSPPSLHHPSTQKLTHPLTHPPGCILTTLALVGATRSIRAGDHNRTQRMFRARIYAQGFTLLAMVAGSMYWDSDRKKRKEFEGVLAEQKAKEKNEAWIKELEARDEEEKEMRRMRDERRRRAEGKSAASGLVVDAANAGAEEGEKTKNGIVDQMKGMVWGKK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SDHF1_YEAST
Sequence: MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  Acts together with SDHAF3 (SDH7).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 1, mitochondrial, SDH assembly factor 1, SDHAF1.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF1 subfamily.
Protein: NUSB_STAAM
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: GUAA_STRA1
Sequence: MTDISILNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITADEIRDINPIGIVLSGGPNSVYADGAFGIDEEIFELGIPILGICYGMQLITHKLGGKVLPAGEAGHREYGQSALRLRSESALFAGTPQEQLVLMSHGDAVTEIPEGFHLVGDSVDCPFAAMENTEKQFYGIQFHPEVRHSVYGNDILKNFAVNICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQRAIGDQLTCIFVDHGLLRKNEGDQVMDMLGGKFGLNIIRVDASKRFLDLLSGVEDPERKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RRF_CALS4
Sequence: MSDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPEPRVLVVQPWDVSQIGEIEKAIQKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKAEEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQKLTDKYIKEIDKMVEAKEKEIMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PSESM
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQMRMAASRPYAERIRQVIGHLANANPEYLHPFMIERPLKRVGYVVVSSDRGLCGGLNTNLFKTLVKDMAVNRENGVEIDLCVVGSKGAAFFRNFGGNVVAAISHLGEEPSINDLIGSVKVMLDAYLDGRIDRLSVVSNKFINTMTQQPTVEQLIPLVATPDQGLKHHWDYLYEPDAKELLDGLMVRYVESQVYQAVVENNAAEQAARMIAMKNATDNAGDLISDLQLIYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS4_SERP5
Sequence: MIIPALDLIDGNVVRLHQGDYGQQRDYGNDPLLRLQDYQQQGAQVLHLVDLTGAKDPTARQIPLLRKLLAGVNVPVQVGGGIRNEQDVAALLEAGATRVVIGSTAVKQPQLVQGWFERYGADAMVLALDVRIDADGTKRVAISGWQENSDATLEQVVEQFLPYGLKHVLCTDISRDGTLAGSNVALYQEISQRYPQIAFQASGGIGNLDDIAQLRGSGVEGVIVGRALLEGKFSVEEAIACWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYH1_SCHPO
Sequence: MSDSNHSLDLHSYTQLEVERFRESLIQFYDKTKRILPWRKKECIPPSEDSPLEDWEQPVQRLYEVLVSEIMLQQTRVETVKRYYTKWMETLPTLKSCAEAEYNTQVMPLWSGMGFYTRCKRLHQACQHLAKLHPSEIPRTGDEWAKGIPGVGPYTAGAVLSIAWKQPTGIVDGNVIRVLSRALAIHSDCSKGKANALIWKLANELVDPVRPGDFNQALMELGAITCTPQSPRCSVCPISEICKAYQEQNVIRDGNTIKYDIEDVPCNICITDIPSKEDLQNWVVARYPVHPAKTKQREERALVVIFQKTDPSTKEKFFLIRKRPSAGLLAGLWDFPTIEFGQESWPKDMDAEFQKSIAQWISNDSRSLIKKYQSRGRYLHIFSHIRKTSHVFYAIASPDIVTNEDFFWISQSDLEHVGMCELGLKNYRAALEIKKRKVTSLSNFKEPKLTSARRIVTKAEC
What is the function of this protein?
Adenine glycosylase active on G-A mispairs.  Has glycosylase and nicking activities and is active at A/G and A/GO sites.
What are the official names of this protein?
Adenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: H2B1A_RAT
Sequence: MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells.  Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones.  Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 1-A, Histone H2B, testis, Testis-specific histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SPED_SHIF8
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: Y830_PASMU
Sequence: MMIINVLLCLGIFCFLLYAFYDQFFMDCWKGKTLLKVHLKKQGQKDALIFSLLIGIIIYQTYTNLSSATLYLLTALILLSVYAAFIRAPMLLLKEKGFFFGNIYFQYADIHQVNLAENNILVIDMKNGKRLLVHLLTDQDREQVIQFFGGYK
What are the official names of this protein?
UPF0266 membrane protein PM0830.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2304_MYCTU
Sequence: MSHDIATEEADDGALDRCVLCDLTGKRVDVKEATCTGRPATTFEQAFAVERDAGFDDFLHGPVGPRSTP
What are the official names of this protein?
Uncharacterized protein Rv2304c.