PharMolix/UniProtQA huggingface dataset:
Protein: BPT_BURMS
Sequence: MTHPTELPLSPLSALQFYATAPYPCSYLDGRVARSQVATPSHLINSDIYTELVKAGFRRSGVFTYRPYCDGCRACVPVRVPVDAFAPNRTQRRTWKRHRALVATVAALHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFRDLDPAENGASTLRMVSMIDILGDGLSSVYTFFDPDESHASYGTYNILWQIEQAKSLRLPYVYLGYWIRESPKMAYKANFHPLEGLVDGRWKVLDPTLADLPPVDAALARAPLPGGHSGTR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_GVAIS
Sequence: MAHYAKRVEIRAIIEELVLAKAQPTDDASESGYDRNMYLNTLFGYIALVGTSKKAIHYGEVDIVGPKASKKTGIDPRGKMVVSELVGRMRTLSVAVSEGPVKGATLRQMCEPFAQNAYDFLVVMAEMGTYSQLATKMTRSGFKEPQVMFDFASGLDLKALTLQEATVIQAMHSRLFRTEGAKGVFNAQSSIGEQAVEI
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: ANM3_MOUSE
Sequence: MCSLAAGNGRGAELGPEPLELSDSGDDAGWEDEDADTEPAHGRQHTPCLFCDRLFASAEETFSHCKLEHQFNIDSMVHKHGLEFYGYIKLINFIRLKNPTVEYMNSIYNPVPWEKDEYLKPVLEDDLLLQFDVEDLYEPVSTPFSYPNGLSESASVVEKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTLTLNSSTQTYSLQ
What is the function of this protein?
Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (By similarity).  May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C555_CHLTI
Sequence: YDAAAGKATYDASCAMCHKTGMMGAPKVGDKAAWAPHIAKGMNVMVANSIKGYKGTKGMMPAKGGNPKLTDAQVGNAVAYMVGQSK
What is the function of this protein?
This basic c-type monoheme cytochrome has been found exclusively in the green photosynthetic bacteria, although its role in bacterial photosynthesis is not established.  It has an unusually low redox potential compared with mitochondrial cytochrome c.  It is reactive with cytochrome c oxidases but not with reductases.
What are the official names of this protein?
Cytochrome c-555, Cytochrome c555.
Protein: FUR_VIBVU
Sequence: MSDNNQALKDAGLKVTLPRLKILEVLQQPDCQHISAEDLYKKLIDLGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELSTQHHHDHLVCLDCGEVIEFSDDIIEERQKEIAAAYNVQLTNHSLYLYGKCGDGSCKGNPDAHKRKN
What is the function of this protein?
Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSD_UREPA
Sequence: MNDYKQFFPWFKNNKDVIYLDSSATSLKPQVVIDAIVDYYTKYSTNPHNTDSNFTFHTHEIMNETRANVAKFINANFDEIIFTSGATESLNLIANGLRPHLKKGDEIILTYIEHASNLLPWYKLRDDLGVKIIFANQKNQFPQLSDFLKVISPKTKVVSFASGGNLIGNVLDENLIIKNIKKIKPDVLVCVDATQSIQHRMFDVKKCKSDFMVFSAHKLLGPTGIGVAYIKNDLIKKMQPLKYGGGMNFSIDLNSYQLYDNYMKFEGGTPHVAGFYGFNAALKFLMDIGYNKIHEHELKITKYARDQLALIPEIKTYVQDATSSTITFSYNGVFCQDFANYLGSKNIIVRSGLSCAKIINNVIQTECAIRASFYIYNDFNDVDRLIKAIKEYQKGDELNGIL
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: SYS_CHLTA
Sequence: MLDIRLIRKEPKECESRLQKKDPAISLERLLDLDKTVRQLKADSEALLAKRKVLSGQIHKAKVANENADALIQEVNTIADQLVAFETTLQEQEALLEDLMARLPNYPDEDVPVSPDKTGNQVIKGHGEVPTFPFPPKHHMQLNEALQILDFKLPAKTTGSGWPAYCNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGDQSLFLIPTAEVVLNGFHSQEILNEQDLPLCYAAFTPCFRREAGAGGAHERGLVRVHQFHKVEMFAFTTPEQEEVVYQKMLHVVEEILSELQLPYQLSLLSTGDMSFTAKKTIDAEVWLPGQKAFYEVSSISKCGDFQARRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQQADGSVVIPSVLRPYMNNQEILLPKTVR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL12B_BOVIN
Sequence: MHPQQLVVSWFSLVLLASPIVAMWELEKNVYVVELDWYPDAPGETVVLTCDTPEEDGITWTSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEALSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCWWLTAISTDLKFSVKSSRGSSDPRGVTCGAALLSAEKVSLEHREYNKYTVECQEGSACPAAEESLLIEVVVEAVHKLKYENYTSSFFIRDIIKPDPPKNLQLRPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKNKREKKLFMDQTSAKVTCHKDANVRVQARDRYYSSFWSEWASVSCS
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.
Protein: MC160_MCV1
Sequence: MAHEPIPFSFLRNLLAELDASEHEVLRFLCRDVAPASKTAEDALRALQRRRLLTLSSMAELLCALRRFDVLKVRFGMTRECAGRLLGHGFLSQYRLQVAAINNMVGSEDLRVMCLCAGKLLPPSCTPRCLVDLVSALEDAGAISPQDVSVLVTLLHAVCRYDLSVALSAVAHGHMTVGVGTPVQDEPMDVLEVDDAEPMEATPACDEIGVVKLAGAASAGAPLADGAFAACTSAGKGEDLATSDLTDSEPEDSVFAVADPVYADVDLSMFVRANATADSSMFVNADAGADSSLVNADAGADSSLVNADAGADSSLVNAVADANSSLMRTTSACTDSEPEDSAGPSCAGMALSMFGRAKSVSSLLLRTKASY
What is the function of this protein?
Plays a role in inhibition of host innate immune response.  Reduces TNF-alpha-mediated NF-kappa-B activation.  Interferes with IKK kinase activity and reduces the phosphorylation of both components CHUK/IKKA and IKBKB/IKKB.
What are the official names of this protein?
Protein MC160.
Protein: RR19_OLIPU
Sequence: MTRSLKKNPFVAKHLLRKIEKLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGREHLPVYIIDLMVGHKLGEFSPTINFRGHAKNDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SODM_BACSU
Sequence: MAYELPELPYAYDALEPHIDKETMTIHHTKHHNTYVTNLNKAVEGNTALANKSVEELVADLDSVPENIRTAVRNNGGGHANHKLFWTLLSPNGGGEPTGALAEEINSVFGSFDKFKEQFAAAAAGRFGSGWAWLVVNNGKLEITSTPNQDSPLSEGKTPILGLDVWEHAYYLNYQNRRPDYISAFWNVVNWDEVARLYSEAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], General stress protein 24, GSP24.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_ANAMM
Sequence: MNIFGTDGVRGRANVYPMDPITVLRLGMAIGLEARKVGTQVVLGKDTRISGYMVESALVSGLVAMGVNVGLLGPMPTAAIATLVRNLRASMGVVISASHNSYLDNGVKIFDSEGIKIPLELEEVLESNVRAELSSDLAQVRGMGKVYRIAGAVGRYIEFVKGTFPKRLKLSGMKIVVDCANGAAYHIGGEVFWELGADVVVIGNKPDGLNINHNCGSLHPEGMVQKVLEEGADIGIALDGDADRVVVCDEKGRLVDGDQVIASIMRHLRATKSITDAAVTTMSSKSIDSYARELGVRLHRSEVGDRHLVDTMRRHSCSVGGEKSGHIILWEHSTTSDSLVAALQILSIMLLENKSASSIFGDFVPMPRVHRDIPYSMEFDHIARLIGPTLSDVEQALGRVNGRVIFRRSGTERLIRCVIEGEDPKLVALVADELSIKLRELGVENGVEPEMQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: UPPS_SALPA
Sequence: MLSATQPVSENLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIDALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDISRFNSRLQERIRKSEALTAHNTGLTLNIAANYGGRWDIVQGVRQLAEQVQAGVLRPDQIDEERLGQQICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALHAFANRERRFGGTEPGDDKA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RL23_CLOBB
Sequence: MKLTSHDIIRKPVITEKSMAAMAEKKYTFMVHVNANKSQVKRAVEEVFDVKVKDVNTINGLGKTKRMGVHVGKRSDYKKAIVTLTEESKAIEFFDGLQ
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: URE1_VARPS
Sequence: MATIGRRAYAEIFGPTVGDRVRLADTDLLIEVEADYTLRAGGYGEEVKFGGGKTIRDGMAQSQRTRAQGAVDTVLTNALILDHWGIVKADIGLKDGRIAAIGKAGNPDVQPGVDIVIGPGTEIISCEGNIVTAGGIDSHIHFICPQQIEEALASGITTMLGGGTGPATGTFATTATPGPWHIERMLQAADAFPMNLGFLGKGNASLPDALHEQIEAGVMGLKLHEDWGTTPSAISNCLDVADATDTQVAIHSDTLNESGFVENTIAAVGGRSICAFHTEGAGGGHAPDILRVVGEENFLPSSTNPTMPYTVNTLDEHVDMLMVCHHLDAGIAEDLAFAESRIRKETIAAEDVLHDLGAISMFSSDSQAMGRVGEVVLRCWQTAHKMKLQRGKLPEDSERNDNFRVKRYVAKYTINPAISHGIAHEVGSIEVGKWADLVIWKPAFFGVKPFTLIKGGTIAMAAMGDPNASIPTPQPVHYRPMFGSYGGSLARSSLTFVSQAGLAAGIKERYGLAKHLSAVKNIRNVRKKDLVHNGYTPKMEIDAQTYAVRADGHLLTCDPAVQLPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_DESHY
Sequence: MAVKIKVTLVKSPIGYSENQRKVLKSLGLGKMGSSVVHDDTSSIQGMIRKCAHLVAVENVAE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: VM2E2_PROEL
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVDDYEVVYPRKVTALPKGAVQPKYEDAMQYEFKVNGEAVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIHNDADSTASISACDGLKGYFKLQGETYLIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRYIKLAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYLGRMCDEKYSVGVVQDHSSKVFMVAVTMTHELGHNLGMEHDDKDKCKCEACIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNAPLRTDTVSTPVSGNEFLEAGEECDCGSPENPCCDAATCKLRPGAQCADGLCCDQCRFIEEGIICRRARGDDLDDYCNGISGDCPRNPFHA
What is the function of this protein?
Disintegrin elegantin-2a-f: inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_MAGMM
Sequence: MANHKSALKRIRQSAKRTVANRIDKARMRTFAKKVLAAVEAGDVELAQQTLRDATSVISRTAQRGVIHTNQASRRIARLNSHVKKLAVAAAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DHR2_YEAST
Sequence: MAANSNSRVASNHTSKKQKVRRNIHPFTNNTRIKRASKIVKFNDSGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTTTTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVEGRKFDVKQYYLKAPTDDIVDAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLYAALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWRHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDYVKLPKQSEPEIARSDVTSPVLMLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPHLSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDLIMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSSISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSMLFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEVVTNAAAVAKQKVSDSK
What is the function of this protein?
Probable ATP-binding RNA helicase.  Required for 18S rRNA synthesis.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DHR2, DEAH box RNA helicase DHR2, Helicase JA2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS3_BACHK
Sequence: MGQKVNPIGLRVGVIRDWESRWFAEKDYATLLHEDIKIREYINVRLKDSAVAKVEIERAANRVNVTIHTAKPGMVIGKGGTEVEALRKALNQLTGKRVHINILEVKRADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRAGAKGIKTQVSGRLGGADIARAESYSEGTVPLHTLRADIDYAAVEADTTYGKLGVKVWIYRGEVLPTKKKASEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DEOB_STRPJ
Sequence: MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTLLKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLLLITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETAMIGESFLDKLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_ACTPJ
Sequence: MQMITLAQQAKIASVELAQFENVQKNQALLTIAQQLEQRSAEILAANAKDIEFAKNQGISTAIIDRLLLNESRLQGIANDVRNVAKLADPVGQVIDGGVLNSGLKIERQRVPLGVILTIYEARPNVTIDVASLCLKTGNAVILRGGKETKFTNAVLVEVVQQALETAGLPKLAVQAVTDPDRVLLLELLKLDRYIDMVIPRGGAGLHQFCKENSTIPVIVGGIGVCHMFVEKSADQQKTLELIANAKTQRPSTCNTLETLLVEKAIAVEFLPKLANRMKALGVTLHTDDLQKTEGIEPLDEARMRQEWLSLDLNVVVIDNLTKAVEHIREYGSQHSEAILTSDYQLARQFVAQVDAAAVYINASTRFTDGGEFGLGAEVAVSTQKLHARGPMGLEALTTYKWVCEGDYLVRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VDLC_HELPJ
Sequence: MAVITGASSGIGLECVLMLLNQGYKVYALSRHATLCVALNHALCECVDIDVSDSNALKEVFLNISAKEDHCDVLINSAGYGVFGSVEDTPIEEVKKQFSVNFFALCEVVQLCLPLLKNKPYSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIEPGPVKSNWEKTAFENDERKDSVYALEVNAAKSFYSGVYQKALNAKEVAQKIVFLSMSHKIKARYLIGLKTQLLLALYQILPSSWYDSLFRLVVLGRKRDA
What are the official names of this protein?
Probable short-chain type dehydrogenase/reductase VdlC.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RPOA_AEGTA
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNSIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL4_XYLFM
Sequence: MDLTIVGSDNTLPVSDVVFGREFSEALVHQVVVAYRNTARSGTKAQKSRSQVSGTTKKSKKQKGGGARHGALTAPIFVGGGVAFAAKPRSFSQKVNRKQYRSAICSIFSELNRQGRLKVVDAFDVEVSKTKVFAEKIKSLEVVGVGSSLLIVSDEISECLSLSSRNLPCVDVRSVQALDPVALVGSDVVVLTVGAVKKIEEWLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CYRIA_MOUSE
Sequence: MGNLLKVLTREIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILTDLQAYKGAGPEIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLNALRFTTKHLNDESTSKQIRAMLQ
What is the function of this protein?
May negatively regulate RAC1 signaling and RAC1-driven cytoskeletal remodeling.  May regulate chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions.
What are the official names of this protein?
CYFIP-related Rac1 interactor A.
What is the protein family that this protein belongs to?
Belongs to the CYRI family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: GATA_BRASO
Sequence: MTDLTSLTLAEARKGLADKTFTSLELTDAHLKAIEAARALNAFVMETPDQARAMARDADARIGKGEGGPLAGIPLGIKDLFATKDVRTTACSKILGNFVPTYESTVTAQLWRDGAVMLGKLNNDEFAMGSSNETSCFGPVGNPWRREGSNTTLVPGGSSGGSASAVAALLCMGATATDTGGSIRQPAAFTATVGIKPTYGRCSRWGIVAFASSLDQAGPIARTTRDAAILLRSMAGHDPKDTTSVDIPVPDYEAAIGKSVKGMKIGIPKEYRLDGMPAEIEKLWSEGAAWLKAAGAELVEVSLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKSIGELYENTRAEGFGAEVRRRVMIGTYVLSAGYYDAYYIRAQKVRTLIKRDFEDCFAKGVSAILTPATPSAAFGVGEKGGADPVEMYLNDIFTVTVNMAGLPGIAVPAGKDSQGLPLGLQLIGRPFDEETLFSLGEVIEQAAGRFTPVRWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TPM4_HUMAN
Sequence: MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (By similarity).  Binds calcium (PubMed:1836432).
What are the official names of this protein?
Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with F-actin stress fibers.
Protein: GYRA_RICFE
Sequence: MTDQNFSNLVPVNIEDEMKVSYLDYAMSVIVSRAIPDVRDGLKPVHRRIIYSMYEAGNHASKPYRKSARIVGDVMGKYHPHGDSAIYDSLVRMAQDFSLRLPLVDGQGNFGSMDGDAAAAMRYTESRMAKVSHKLVEDIDKETVSFNPNYDGSEEEPSVLPAMFPNLLVNGSGGIAVGMATNIPPHNLGEVIDACCLYIDNNDIEILDLLEVVKGPDFPTGSMILGISGIRSAYLTGRGSIIMRGRAEIENIGNSRQAIIITEIPYMVNKARLVEKIAEMVKEKRIEGISDLRDESNKNGVRIFIELKKDVVVEVVLNQIYACTQLQTSFGVIMLALKDGLPKVMNLKEVIAAFVSFREVVITNRTIYLLNKARDRAHILLGLTIAVSNIDEIIRIIKASNNPNAAKQELMARSWDALNILPLVKLVDDKAMLNEQGKCSFTEVQAKAILEMRLQRLTAMEKNKLEEDLKNLATEITEYLNILGSRTRLLEILKEELIKVKEEFATPRLTSIEFGEFDQDIEDLIQREEMVVTVTLGGYIKRVPLSSYRAQKRGGKGRSGLSMRDEDITTQVFVGSTHTPMLFFSNIGQVYSLKLYKLPLSNPQGKGRPMVNILPLKENEHITNIMPLPENQDEWDNLNIMFATAKGNIRRSDLLDFKKIQSNGKIAIRLDEDDKLIDVKPCKEDEHILLATKAGKALRFPVESLRVIKSRTSDGVRGMKLAKEDSVISMTVLKGISSTKEDRDAYLTVPWEKRLEIAKGEEFNLEELGVTLTADSILEMANSEEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDINDKTGLVVGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLDDGEKVVSVSLIAETSESEEDSELEEDLEQAEEVYT
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.