PharMolix/UniProtQA huggingface dataset:
Protein: RECR_LEPBL
Sequence: MANHLLEEMVDALSSLPGIGRKSAFRISFHLLRLEQGHFNHFIHQLTNTKNKIKFCKRCGSYAETEICNICTSEKRDTHTFCVVEQPEDIFFIENTREFHGKYHVLNGVISPLEGIGPKDLRIKELLERIEPEQIKEVLVATNPTLEGDATADYLASQLKPLSVDVTRIAYGITVGGSIELADQYTLGRAIRSRLQL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MTH_DROYA
Sequence: MKLFWVKRLLRISTVVVTLLLLQRTNAAIPDCDYYDTVDISAAQKLPNGSYLFEGLLVPANLTAEYEFTILPDDSKQKVDKHIRGCVCKLKPCVRFCCPHNHIMDMNVCAGDMTEEELEVLDPFLNVTLDDGSVVRRHFKKELIVQWDLPMSCDGMFSLDNREKTDQYTLFENGSFFRHHDRVTLNKREYCLQHLTFVDGNESSIRIAPHNCLISPSRMGQTVVMITSLVCMVLTITVYLFVKKLQNLHGKCFMCYMVCLFMAYLLLLLNLWQMSQNFCITAGFLGYFFVMAAFLWLSVISLHLWNTFSGSAHNANRFLSEHRFLAYNTYAWGMAVVLTGITYLADKVVENEDWNPRMGFGGHCWICTQSWSAMLYFYGPMVFLIAFNITMFILTANRIIGVKKDIQKFAHRQERKQKLNSDKQTYTFFLRLFIIMGLTWSLEIGSYISQFNQTWSNVFLVADYLNWSQGIIIFILFVLKRSTLRLLMESIRGEGEEVNDSEEEISLENTKYDRNVL
What is the function of this protein?
Involved in biological aging and stress response.  Essential for adult survival (By similarity).
What are the official names of this protein?
G-protein coupled receptor Mth, Protein methuselah.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TXND9_BOVIN
Sequence: MEANASVDMFSKVLENQLLQTTKLVEEHLDSEIQKLDQMDEDELERLKEKRLEALKKAQQQKQEWLSKGHGEYREIPSERDFFQEDKESKKVVCHFYRDSTFRCKILDRHLVILSKKHLETKFLKLNVEKAPFLCERLRIKVIPTLALVKDGKTQDFVVGFSDLGNTDDFTTETLEWRLGCSDILNYSGNLMEPPFQSQKKFGTNFTKLEKKTIRGKKYDSDSDDD
What is the function of this protein?
Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin.
What are the official names of this protein?
Thioredoxin domain-containing protein 9, Protein 1-4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Co-localizes with beta-tubulin in the centrosome.
Protein: YD290_YEAST
Sequence: MYSFHISATLGASLYCRSNHFEALEIDSWESSNVFNLVVNCSEEKGIPSILILDYCFLQIFYLFVKTFFACTYIIMLAFQVYIFLKEKNNFFIFRYKTEPLYILRWLRS
What are the official names of this protein?
Putative uncharacterized protein YDR290W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: URE1_HELHP
Sequence: MIKISRKQYASMYGPTTGDKVRLGDTNLFAEIEKDYTLYGEEIKFGGGKTIRDGMAQSASTYTNELDAVITNAMIIDYTGIYKADIGIKGGKIVGIGKAGNPDTQDSVNEAMVVGAATEVIAGEGQIITAGGIDTHIHFISPTQIPTALYSGVTTMIGGGTGPAAGTNATTCTPGKWNMHQMLRAAESYAMNLGFFGKGNSSNEEGLEEQIKAGALGLKVHEDWGSTPAAINHALNVAQKYDVQVAIHTDTLNEAGCVEDTMKAIDGRTIHTFHTEGAGGGHAPDIIKAAGEPNILPASTNPTIPFTKNTADEHLDMLMVCHHLDKKIKEDVAFADSRIRPETIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKCKNEFGALKEECGENDNFRIKRYISKYTINPAIAHGISEYVGSVEVGKFADLVLWKPSMFGIKPEMILKNGMIVAAKIGDSNASIPTPEPVVYAPMFGSYGKAKYNCAITFVSKIAYDCHIKEELGLERILLPVKNCRNITKKDMKFNDVITPIEVNPETYEVRVNNTKITSKPVEKVSLGQLYCLF
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_MYCBP
Sequence: MKLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDAILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVREGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNVLTLAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHLGEHDAAARVDRAVEAHLATRGSERLATSDVGERIAAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_STAAM
Sequence: MRHIHLQVFGRVQGVGFRYFTQRIAMNYNIVGTVQNVDDYVEIYAQGDDADIERFIQGVIEGASPASNVTSHQLEELELNQKLSDFRSI
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: BST14_CAEEL
Sequence: MTISYDEEFSSLMLRWRGSIWKAVLKDLIGFYIAYYIVLAFQWYLLDEKGKEYFTGWIMWCEIGAQYIPLSFLLGFFVSLIVARWWEQFNCISWPDKMMIMVSACLPGNENMVVRQTIARWSSLQAAIAWSGVSVKTLKRFPTERHMVASKLMTEEEYDLYMNTDAPHGKWFIPILWIVNLIKKQKQKGIIDSIQMDMLLKQVYSYRDGFAMLFVYDWIKIPLVYTQVVAIATYGYFFICLIGRQPKLDQRSMEKEITILFPIFTTFQMLFYLGWLKVGQYLMNPFGEDDDDFELNYVLDRNTAIAHMMASELSDQLPSIGAPMVPAVPHTRASFKIQDVIPKSHLAGFKLSEAEMKLIKPEDLEEHERLMEETKVTNRQRLGTLVRALEKKSRTNATINEDDEE
What are the official names of this protein?
Bestrophin homolog 14.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COX13_THET8
Sequence: MAITAKPKAGVWAVLWDLLTTVDHKKIGLMYTATAFFAFALAGVFSLLIRTQLAVPNNQFLTGEQYNQILTLHGATMLFFFIIQAGLTGFGNFVVPLMLGARDVALPRVNAFSYWAFLGAIVLALMSYFFPGGAPSVGWTFYYPFSAQSESGVDFYLAAILLLGFSSLLGNANFVATIYNLRAQGMSLWKMPIYVWSVFAASVLNLFSLAGLTAATLLVLLERKIGLSWFNPAVGGDPVLFQQFFWFYSHPTVYVMLLPYLGILAEVASTFARKPLFGYRQMVWAQMGIVVLGTMVWAHHMFTVGESTLFQIAFAFFTALIAVPTGVKLFNIIGTLWGGKLQMKTPLYWVLGFIFNFLLGGITGVMLSMTPLDYQFHDSYFVVAHFHNVLMAGSGFGAFAGLYYWWPKMTGRMYDERLGRLHFWLFLVGYLLTFLPQYALGYLGMPRRYYTYNADIAGWPELNLLSTIGAYILGLGGLVWIYTMWKSLRSGPKAPDNPWGGYTLEWLTASPPKAHNFDVKLPTEFPSERPLYDWKKKGVELKPEDPAHIHLPNSSFWPFYSAATLFAFFVAVAALPVPNVWMWVFLALFAYGLVRWALEDEYSHPVEHHTVTGKSNAWMGMAWFIVSEVGLFAILIAGYLYLRLSGAATPPEERPALWLALLNTFLLVSSSFTVHFAHHDLRRGRFNPFRFGLLVTIILGVLFFLVQSWEFYQFYHHSSWQENLWTAAFFTIVGLHGLHVVIGGFGLILAYLQALRGKITLHNHGTLEAASMYWHLVDAVWLVIVTIFYVW
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  Co I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B.  This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.
What are the official names of this protein?
Cytochrome c oxidase polypeptide I+III, Cytochrome c aa(3) subunit 1, A-protein, Cytochrome caa3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MINE_XYLFA
Sequence: MGLIDFLRNKTKTAETAKNRLQIIIAQERTQRGGPDYLPLLQRELLEVIKKYVKIDADAVKVDLIKDGANDVLDISVALPDDSER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity).
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SARX_STAAC
Sequence: MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
What is the function of this protein?
Involved in the regulation of virulence genes.  Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb.  Binds directly to the agr promoter region (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarX, Staphylococcal accessory regulator X.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPIKE_BC512
Sequence: MKYTLLFCVVFATVSFGFADNERCNKTVNLTRLFSKFDIQPPSQVVLAGLLPNQTAQWKCTTETNKRDEGVGVKGVFLSYVSSGRGFTIGVSQYNFDPSTYQLYLHRDTNGNSNAFAYLRICKWPSKKWLQSTSNMDTSGRFCLVNKKIPAAFTDHANMVVGITWDQDRVTFYTDKVYHFYVPNNRWSRVVSWCSAADSCAMQYINSTIYYNLNVTTPGPGGITYSVCTKHCTGLADNVFSTDQGGHIPPIFPYNNWFLLTNTSTLVQGVTRVFQPFLVNCLVALPKLQGLTTTLSFDSPLNVPGFSCNGANGSSSAEAFRFNVNDTKLFVGAGAVTLNTVDGVNVSIVCSNNATQPTRSNNLQEDLPYYCFTNTSSGTNHTVKFLSVFPPIIREFVITKYGNVYVNGYIYLRTRPLTAVHLNASSHSQDVAGFWTIAATNFTDVLVEVNNTGIQRLLYCDTPENSVKCSQLSFELEDGFYSMTADNVYAVTKPHTFVTLPTFNDHGFVNVTVGGNFDSSYPPKFTANGTLVNNGTVVCVTSNQFTLRHDFMVGYSADMRKGIFEYSSTCPFNRETINNYLTFGRICFSTSPADGACELKYYVWNTIGAVSHLAGTLYVQHTKGDIITGTPKPLQGLNDISELHLDTCTTYTIYGFRGDGVIRLTNQTFLSGVYYTSESGQLLAFKNVTTGQIYSVTPCQLVQQVAFVEDRIVGVISSANNTGFFNSTRTFPGFYYHSNDTTNCTSPRLVYSNIGVCTSGAIGLLSPKAAQPQVQPMFQGNISIPTNFTMSVRTEYIQLFNKPVSVDCAMYVCNGNDRCKQLLSQYTSACKNIESALQLSARLESMEVNSMLTVSDEALKLATISQFPGGGYNFTNILPANPGARSVIEDILFDKVVTSGLGTVDEDYKRCSNGLSIADLACAQHYNGIMVLPGVADWEKVHMYSASLVGGMTLGGITSAAALPFSYAVQARLNYVALQTDVLQRNQQMLANSFNSAISNITLAFESVNNAIYQTSAGLNTVAEALSKVQDVVNGQGNALSQLTVQLQNNFQAISNSIGDIYSRLDQITADAQVDRLITGRLAALNAFVAQSLTKYAEVQASRTLAKQKVNECVKSQSPRYGFCGDEGEHIFSLTQAAPQGLMFLHTVLVPNGFINVTAVTGLCVDETIAMTLRQSGFVLFVQNGNYLVSPRKMFEPRRPEVADFVQVKTCTISYVNITNNQLPDIIPDYVDVNKTIDEILANLPNNTVPDLPLDVFNQTFLNLTGEIADLEARSESLKNTSEELRQLIQNINNTLVDLQWLNRVETFIKWPWYVWLAIVIALILVVSLLVFCCISTGCCGCCGCCGSCFSGCCRGTKLQHYEPIEKVHVQ
What is the function of this protein?
S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection.  Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion.  S2 region belongs to the class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly.
Protein: PARC_TRYBB
Sequence: MAPRSLYLLAVLLFSANLFAGVGFAAAAEGPEDKGLTKGGKGKGEKGTKVGADDTNGTDPDPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAATLKSVALPFAIAAAALVAAF
What is the function of this protein?
Major surface antigen of procyclic forms.
What are the official names of this protein?
Procyclic form-specific polypeptide B-alpha, PARP B-alpha, PSSA-1, Procyclin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: SGS8_DROME
Sequence: MKLLVVAVIACIMLIGFADPASGCKDCSCVICGPGGEPCPGCSARVPVCKDLINIMEGLERQVRQCACGEQVWLF
What are the official names of this protein?
Salivary glue protein Sgs-8.
Protein: MIER1_CHICK
Sequence: MAEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGERNFNSEIEDLNRESDMPIQELLSLYGYDGTIPLQEDDDDEDEEEEEEEGEDDDDVDNDDNSGCSGENKEETIKDSSGQEDDTQSSNDDPAPSVASQDPQELIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPAGICRYKENEKVYENDDQLLWNPDVLPEDKVIEFLNEASRRTGDEKGLDAIPEGSHIKDNEQALYELVKCNFDTEESLRRLRFNVKAAREELSVWTEEECRNFEQGLKVYGKDFHVIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEREDSTTSSSNQNGLSANGPGDIPSKDEAKPEGLHINGPTGGKKTPHTDLDTNGYETESLSLDPKVAHSTSRSENDFEEKNERPLKRRRINSNGKESPGSSEFFQEANSHGKLEELETLDD
What is the function of this protein?
Transcriptional repressor regulating the expression of a number of genes.  Probably functions through recruitment of histone deacetylases involved in chromatin silencing (By similarity).
What are the official names of this protein?
Mesoderm induction early response protein 1, Mi-er1.
What are the subcellular locations of this protein?
Nucleus.
Protein: A1CF_RAT
Sequence: MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDTTPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKQEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRRLLPGRIQLWGHPIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNSIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRNTMLQEYTYPLSHVYDPTTTYLGAPVFYTPQAYAAIPSLHFPATKGHLSNRALIRTPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRQDKLYDLLPGMELTPMNTISLKPQGVKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKVTIPALASQNPAIHPFTPPKLSAYVDEAKRYAAEHTLQTLGIPTEGGDAGTTAPTATSATVFPGYAVPSATAPVSTAQLKQAVTLGQDLAAYTTYEVYPTFAVTTRGDGYGTF
What is the function of this protein?
Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA.  Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine.  The complex also seems to protect the edited APOB mRNA from nonsense-mediated decay (By similarity).
What are the official names of this protein?
APOBEC1 complementation factor, APOBEC1-stimulating protein.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm. Note=Predominantly nuclear where it localizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum. Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1.
Protein: APX7_ORYSJ
Sequence: MAAQRLAALHAAAPSAFSSTSSASHGRPAARSSTTALLPVALPRASATLRAAPSRLLPQEAKAAGSGRSVMCMASASASAASAAVASGAAELKAAREDIRELLKTTHCHPILVRLGWHDSGTYDKNIKEWPQRGGANGSLRFDVELKHGANAGLVNALKLVQPIKDKYPNISYADLFQLASATAIEEAGGPKIPMTYGRIDVTGPEQCPPEGKLPDAGPSAPADHLRKVFYRMGLDDKEIVVLSGAHTLGRSRPERSGWGKPETKYTKNGPGAPGGQSWTAEWLKFDNSYFKEIKEKRDQDLLVLPTDAALFEDPTFKVYAEKYAEDQEAFFKDYAGAHAKLSNLGAKFNPPEGFTLDG
What is the function of this protein?
Plays a key role in hydrogen peroxide removal.
What are the official names of this protein?
Probable L-ascorbate peroxidase 7, chloroplastic, OsAPx7.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ESTE_SFAVA
Sequence: MCVNRVRSIVSLTLIAYLSVLMGVSVYFYVLIESVYQQFSDMSENYVQLVKDTSSTPIVVATHGHSTNRSHQSVLFTARADVNISMETILHVEFNYTTALGTMDDTFNIINFYGLKYRHVDLIDPFGNSLPVVNSKSSFGFTDCSSDERVRCPSTRRPFTGTLDCLTLDMHMQSWNRDRSTDHFKRPIIIWLGEIMGSLWRLIGNGVIVIRVNYRRGVYGFVCHRDERLPYYNQGVNDVMHAIEWVTENAERFAGDTKRITLAGHGDDGKVVEYVRMYHSHHLPLDKYIVMSAAETGSRDLTCSSNSNILVTAARILGMPSVPVHDTTAGERGVYDAVRYLSFIEPKRLMERLYDLKEIFQPCPGEIRSTASDVNGLGKAFEGVDSDDCKFINTDTPVLYMNTLNEYANKVKLDDSFMHARAHTLRRVIEHVLARRFKPHRVTRYCNVTISEPAEIGSERYEPCDGEVINVESLGRVLTDFEYIAPTSRICEAAVGCGASFYHYVYDFKNASHGDDLRLLMSEHDQRNLTKFERQLADGIGMMISRFVRRGYPVVKRDNWCSSTSLVAQIMEINTTPNVITTQTQVRGTVER
What are the official names of this protein?
Putative esterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y968_MYCTU
Sequence: MVWHGFLAKAVPTVVTGAVGVAAYEALRKMVVKAPLRAATVSVAAWGIRLAREAERKAGESAEQARLMFADVLAEASERAGEEVPPLAVAGSDDGHDH
What are the official names of this protein?
Uncharacterized protein Rv0968.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1991c and Rv3269.
Protein: RNY_GEOSL
Sequence: MKIELAIIFIVLAAGAGFLIGNLLRKKLSDSLVSKAEELASRIVEDAKREAETISKEAALQAKDVVYQAKADFEREAKEKHKDLQTLEKRLQQKEENLDKKMNLFDQRDADLTKKEQGILAREQSLNRKEESLDALVAEQRAKLEQISGMSSAEAKKILMDAMESEAKLDAAKRIKAIEEEARETADKKSKEIISLAVQRYAGEYVAEKTVSVVALPSDEMKGRIIGREGRNIRALEAATGIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQAVKEAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNSILAVLVQAADALSGARPGARREMMETYVKRLEDLERISCSFGGVNNSFAIQAGREIRVMVSSEEVSDERAVLLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MDTH_ECO57
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSVHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA
What is the function of this protein?
Confers resistance to norfloxacin and enoxacin.
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HBB_PANPO
Sequence: MSFLSAEEKNLVSGLWGKVNVDEVGGEALGRLLVVYPWTQRFFQSFGDLSSADAIMSNAKVKAHGKKVLNSFSDGLKNIDDLKGAFAKLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGHEFNPQVQAAFQKVVAGVASALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TYRO_FELCA
Sequence: MLLAALCCLLWSFRTSAGHFPRACASSKSLMEKECCPAWTGDSSPCGQLSGRGACQDITLSKAPLGPQYPFTGMDDREAWPSVFYNRTCQCFGNFMGFNCGNCKFGFWGPNCTEKRLLVRRNIFDLSVPEKNKFLAYLTLAKHTISPDYVIPIGTYGQMNNGSTPMFNDINVYDLFVWMHYYVSRDTLLGGSEIWKDIDFAHEAPGFLPWHRLFLLLWEQEIQKLTGDENFTIPYWDWRDAKSCDICTDEYMGGHNPANPNLLSPASFFSSWQIICTRLEEYNSRQALCDGTPRGPLLRNPGHDKARTPRLPSSADVEFCLSLTQYESDSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHHPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSRDLGYDYSNLQDSERDIFQDYIKPFLEQASRIWPWLIGAAVVGSVLTAVLGRLTSLLCRRKRKQLREERQPLLMEKEDYHSLLYQTHV
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (By similarity).  Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity).  In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (By similarity).
What are the official names of this protein?
Tyrosinase, Monophenol monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: RL3_MYCMM
Sequence: MARKGILGTKLGMTQVFDENNKVVPVTVVKAGPNVVTRIRTPERDGYSAVQLAYGEISPRKVNKPVTGQYTAAGVNPRRHLAELRLDDAEAVTEYEVGQELTAEIFADGSYVDVTGTSKGKGFAGTMKRHGFSGQGASHGAQAVHRRPGSIGGCATPARVFKGTRMAGRMGNDRVTVQNLLVHKVDAEQGVLLIKGAVPGRTGGLVMVRSAIKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CALM_LYTPI
Sequence: KKMKDTDSEEEIREAFRVFDKDGNGFI
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: CYSI_SHESA
Sequence: MSEQKLALNEYLKTDSDYLRGTIKEGLDSSVTGSFSDGDQQLIKFHGFYQQDDRDLRNERKEQKLEPLYSFMLRARVPGGVCTPKQWLGVDEIASTLTSSNSIRLTTRQTFQYHGIPKRNLKTIIQGLDREALDSIAACGDVNRNVMCNPNPVESKLHAQAYEVAKKLSDHLLPHTRAYAEIWLDEEKLLTTEDETVEPVYGKTYLPRKFKMAVAVPPDNDVDVYTNDLGFIAVAENGELVGFNLTAGGGMGSTHGEVETFPRLADDFGFIKTEDVMKFAEAVMTVQRDWGNRTNRKRSRLKYTIVDHGYEKFKAEVEARAGVKFEPKRDVVIGDRGDRYGWVEGVDGKWHLTLFIESGRIKDVPGKSLQTGMREIAKIHKGDFRMTSNQNMIIAGVAPEDKATIEGLARKHGLLGQVLTQTRGHSIACVALPTCPLAMAEAERYFPEFIDHIDALQAKNGISDQAIVVRMTGCPNGCARPFAAEIGLVGKAPGRYNLYLGANFEGTRLNKMYRENIQEAEILAELDALFARYAVERNAGETFGNFTVRTGVVKAVIDAAKDFHG
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: SYC_PARD8
Sequence: MEHPLNIYNTLTRKKEQFIPLHEPHVGMYVCGPTVYGDAHLGHARPAITFDLLFRYLTHLGYKVRYVRNITDVGHLEHDADDGEDKIAKKARLEQLEPMEVVQYYLNRYHQAMDALNVLPPSIEPHASGHIIEQIELVKKILDNGYAYESQGSVYFDVEKYNKDHKYGILSGRNIEDMLNTTRALDGQDEKHNAIDFALWKCAQPEHIMRWPSPWSDGFPGWHCECTAMGKKYLGEHFDIHGGGMDLIFPHHECEIAQAVASQGDDMVHYWMHNNMITINGQKMGKSLGNFITLEQFFTGDHPSLQQAYSAMTIRFFILQAHYRSTVDFSNEALQAAEKGLSRLMEAYGHLMKLQPSATSTVDTKGLREKCFEAMNDDLNSPIVISHLFDATRAINSVKDGKATLSEEDLKELQEVFHLFLFDILGMKDEASASGNHYEAFGKAVDLLLSIRQQAKANKDWATSDKIRNELTAMGFEIKDTKDGAEWKLSK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_THEYD
Sequence: MKLALVSAEAYPFSKTGGLGDVVGSLFKEFIKAGIDVTLFLPFYKITRDNFSNSVVNAEIVYGAPIGLNTLFGAVRVAKVSVDSDDNLIIEPSKKGNLFFIEHNNFFDRNELYGTNHGEYLDNAERFVFFSRAVLEICKIMNLNFDVIHCHDWHTALIPLYLKTLYRECSCFEKTKTVLTVHNLGYQGIFPREKLELTGFGQEMFHIDGLEFYGMVNFLKGGLFNADIITTVSPTYAKEILTPDYGAGLDGVLRKRKENLVGIINGIDYKIWNPEEDPFIAKKYGLQNINDKQKNKEDLIALAGINSSLQDPIIAFIGRMVYQKGIDIVVDAMPNLIKNGISFIFEGTGESYYEHKIRELQNSYPSKVFAFIGFDEALAHKIYAGADSLLVPSRYEPCGLSQLIAMRYGTIPICRKTGGLSDTVEDKVTGFLFSEYSSSALTHAISRFIEIYNNKQKFLEMIREAMKRDFSWSNSSKKYIELYRGLIGERERKTGTI
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.