PharMolix/UniProtQA huggingface dataset:
Protein: MNME_ZYMMO
Sequence: MKTIFALSSGRPPAGIAVIRISGSAAADTACLLTRKKIPEARRAVLRNLYDPDSGEQLDQSLLLWLPAPKTVTGEDLLELHVHGGRAVIDAVLKTLEKLPDLRPAEAGEFTRRAFENGVISLHEAEGLGDLLTAETASQRRAALMMSGGALGRQISAWQDRLLALSGQIEASFDFAEDIEEDETESRQHLAVMKDKIAALIAEHRQFENRPTMERLRDGLRVVLAGRPNAGKSTLINALTGQDIAITAPIAGTTRDVIEVSFALKGIPMRFSDTAGLHESDDLIEKAGIERAQRAIEEADILLWLGQAEEAPKTDGEVLVLYPQIDLPERHPIPEKIDIAVSAVTGEGIDRLQEKLVEIGKKILPKEDEVTLNRRQRQLVKEAADSLALALDAEDMLIIAEAIRQACRCYDRLTGKAGVENMLDNLFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_BACLD
Sequence: MKIGIIGATGYGGAEIMRIMRTHPYADECILYSSSDEGARYDAAYPHLVKLTDQHLQPIEVKRIANEIDFLFMAAPPGISSRLTPQFDAYDIPIIDLSGDLRIQNPSVYEKWYKREAAPEHVLQKAVYGLSELNREDIKTAQYIANPGCFPTAVLLGLAPLVKSGSINESFVIIDAKTGVSGAGRKPSMGTHFSEVNDNFKIYKVNEHQHTPEIEQTVKQWNSAFKPITFSTHLVPMTRGIMATIYTELKDSMDAEQLQLIFSKFYKDSYFVRVRETGSFPATKEVYGSNFCDIGVTVDERTNRVTIVSVIDNLMKGAAGQAVQNFNIMNGLSETAGLEFTPIYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PROM2
Sequence: MTSTLNTLKSNSGSRKKKLRKGRGIAAGQGASCGFGMRGQKSRSGRPTRPGFEGGQMPLYRRVPKLKHFEIINQKNFSIINLEKLNDFKDNDTVNIDSLVKKGLIFKPKFPLKILGNGKINVKLKVQAHAFTKVAKQKIEAAGGSCELINNK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FMT_CORU7
Sequence: MKILFAGTPKPAAIVLEHLLTDPRLEVLGVITQPDARRGRGRSLHPSPVAEVAEGAGLKVHKWHSLGASSEDAAAVRETLAAYREAGATAVAVVAYGNLIPADLLDAVEHGWVNLHYSLLPRWRGAAPVQAAIAAGDQETGATIFRIEQGLDTGPMLSKKAYEIGIRETAEEVLIELTNSGKSLLADTLVELGEGSATPQPQPEEGATHAPKLHPADARIDFSAPAKVIQRRARAHTPAPGAWCTLDGQRYKFGLMLPVAEGEEFPELAPGQLWADKTRVLVGTGDTPLLVETIQPPGKKMMRAADWARGQQELLAQSPRFDIEEDTAK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PIT1_MOUSE
Sequence: MSCQSFTSADTFITLNSDASAALPLRMHHSAAECLPASNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPLHQPLLAEDPAASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISVAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
What is the function of this protein?
Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary.  Activates growth hormone and prolactin genes.  Specifically binds to the consensus sequence 5'-TAAAT-3'.
What are the official names of this protein?
Pituitary-specific positive transcription factor 1, PIT-1, Growth hormone factor 1, GHF-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIN7_YEAST
Sequence: MGIPGLLPQLKRIQKQVSLKKYMYQTLAIDGYAWLHRASCACAFELVMNKPTNKYLQFFIKRLQLLKRLKIKPYIVFDGDSLFVKNHTETRRRKKRLENEMIAKKLWSAGNRYNAMEYFQKSVDITPEMAKCIIDYCKLHSIPYIVAPFEADPQMVYLEKMGLIQGIISEDSDLLVFGCKTLITKLNDQGKALEISKDDFSALPENFPLGELSEQQFRNLVCLAGCDYTSGIWKVGVVTAMKIVKRYSEMKDILIQIERTEKLCFSKAFKQQVEFANYAFQYQRVFCPLSNQITTLNNIPKAVTNSHAEIIKIMKCIGSVVERGSGVRKDVINTKNIDHKVHEMIAKGELHPVDMASKLINRERKLKARKLFKVGLLGGESNSFNKKVEQPLVDTQDVLSERENSLDNKNASSIYMTSPAAISGTVPSIF
What is the function of this protein?
5'->3' double-stranded DNA exonuclease.
What are the official names of this protein?
DNA damage-inducible protein DIN7.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPS_SALTY
Sequence: MLSATQPVSENLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIDALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDISRFNSRLQERIRKSEALTAHNTGLTLNIAANYGGRWDIVQGVRQLAEQVQAGVLRPDQIDEERLGQQICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALHAFANRERRFGGTEPGDDKA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ITAE_MOUSE
Sequence: MKWLFHTLLCMASLKPQGAFNLDVDWAWVTALQPGAPAVLSSLLHQDPSNNQTCLLVARRSSNRNTAALYRCAISISPDEIACQPVEHICMPKGRYQGVTLVGNHNGVLVCIQVQARKFRSLNSELTGACSLLTPNLDLQAQAYFSDLEGFLDPGAHVDSGDYCRSKGGSTGEEKKSARRRRTVEEEDEEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPLNLTTVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTFKVTNYSALDGLLSKLQQHIVHMEGTVGDALQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALLYSTQNGRGCFLNQTAKEDSRTVQYSYLGYSLAVLHKAHGVSYVAGAPRHKLRGAVFELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYHIRGEEGRVYVYQVPEQDASFSLAHTLSGHPGLTNSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSGGLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMVFIGKMDVKLCFEVDSSGVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWNGGSFLCEHFWLISTEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSSVNVSVTWQLEESVFPNRTADITVTISNSNEKSLARETRSLQFRHAFIAVLSRPSVMYMNTSQSPSDHKEFFFNVHGENLFGAVFQLQICVPIKLQDFQIVRVKNLTKTQDHTECTQSQEPACGSDPVQHVKEWHSVVCAITSNKENVTVAAEISVGHTKQLLRDVSELPILGEISFNKSLYEGLNAENHRTKITVIFLKEEETRSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYQQLNLESTRRAQLKADSLLQD
What is the function of this protein?
Integrin alpha-E/beta-7 is a receptor for E-cadherin.  It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.  Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
What are the official names of this protein?
Integrin alpha-E, Integrin alpha M290.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL31_SYNP2
Sequence: MPKADIHPEWYPDAKVICNGEVVMTIGSTQPEINVEIWSGNHPFYTGTQKIIDTEGRVDRFLRKYGMLSNNSDDQK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RR15_LOBMA
Sequence: MIKNAFISFQEKKEESKGSVEFQVFSFTNKIRRLTSHLELHRKDYLSQRGLRKILGKRQRLLAYLSKKNRVRYKELIKQLNIRELKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACHD_TETCF
Sequence: MGNIHFVYLLISCLYYSGCSGVNEEERLINDLLIVNKYNKHVRPVKHNNEVVNIALSLTLSNLISLKETDETLTSNVWMDHAWYDHRLTWNASEYSDISILRLPPELVWIPDIVLQNNNDGQYHVAYFCNVLVRPNGYVTWLPPAIFRSSCPINVLYFPFDWQNCSLKFTALNYDANEITMDLMTDTIDGKDYPIEWIIIDPEAFTENGEWEIIHKPAKKNIYPDKFPNGTNYQDVTFYLIIRRKPLFYVINFITPCVLISFLASLAFYLPAESGEKMSTAISVLLAQAVFLLLTSQRLPETALAVPLIGKYLMFIMSLVTGVIVNCGIVLNFHFRTPSTHVLSTRVKQIFLEKLPRILHMSRADESEQPDWQNDLKLRRSSSVGYISKAQEYFNIKSRSELMFEKQSERHGLVPRVTPRIGFGNNNENIAASDQLHDEIKSGIDSTNYIVKQIKEKNAYDEEVGNWNLVGQTIDRLSMFIITPVMVLGTIFIFVMGNFNHPPAKPFEGDPFDYSSDHPRCA
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: FTSW_MYCTU
Sequence: MLTRLLRRGTSDTDGSQTRGAEPVEGQRTGPEEASNPGSARPRTRFGAWLGRPMTSFHLIIAVAALLTTLGLIMVLSASAVRSYDDDGSAWVIFGKQVLWTLVGLIGGYVCLRMSVRFMRRIAFSGFAITIVMLVLVLVPGIGKEANGSRGWFVVAGFSMQPSELAKMAFAIWGAHLLAARRMERASLREMLIPLVPAAVVALALIVAQPDLGQTVSMGIILLGLLWYAGLPLRVFLSSLAAVVVSAAILAVSAGYRSDRVRSWLNPENDPQDSGYQARQAKFALAQGGIFGDGLGQGVAKWNYLPNAHNDFIFAIIGEELGLVGALGLLGLFGLFAYTGMRIASRSADPFLRLLTATTTLWVLGQAFINIGYVIGLLPVTGLQLPLISAGGTSTAATLSLIGIIANAARHEPEAVAALRAGRDDKVNRLLRLPLPEPYLPPRLEAFRDRKRANPQPAQTQPARKTPRTAPGQPARQMGLPPRPGSPRTADPPVRRSVHHGAGQRYAGQRRTRRVRALEGQRYG
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: RL35_RHOOB
Sequence: MPKSKTHSGTAKRFKVSGSGKILRQKAGRRHLLEHKATKVTRRLDGVAVVSKADTPRIKRLLDI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: YM12A_YEAST
Sequence: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-ML2 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAYP1_RABIT
Sequence: MDTADAIVEKLRAQCLARGAAGIQGLARFFRRLDRDGSRSLDAGELRQGLAKLGLALDEAEAQSVCRRWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTLGDLRGVYSGRNHPKVRTGEWTEDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGLSASVDTDEEFVAMMSSAWQL
What is the function of this protein?
Calcium-binding protein.  May play a role in cellular signaling events (Potential).
What are the official names of this protein?
Calcyphosin, Calcyphosine, R2D5 antigen.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_METPB
Sequence: MTAITNIAAREILDSRGNPTVEVDVLLEDGSFGRAAVPSGASTGAHEAVELRDGDKGRYNGKGVLKAVDAVQTEILDAIGGMDAEDQVAVDEAMITLDGTPNKARLGANAILGVSLAVAKAAAETAGLPLYRYVGGVQGRVLPVPMMNIVNGGAHADNPIDFQEFMVMPVGATSLSDAVRMGAEIFHTLKSALKKAGHNTNVGDEGGFAPNLPSAEAALDFVMESINAAGFKPGSDVVLALDCAATEFFKDGAYHYEGEGQTRSIEQQVEYLAKLTEAYPILSIEDGMSEDDWEGWKLLTDRIGNRVQLVGDDLFVTNVERLARGIETGTGNSILVKVNQIGSLTETLAAVDMAQRAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEGLGAQALYAGRSAIRQLAGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRFE_ONCKI
Sequence: MKLLLVSALLGCFATVYAAPAEGMVRWCVKSEKELKKCHDLAANVAGFSCVRRDDSLECIQAIKREEADAITLDGGDIYIAGLHNYNLQPIIAEDYGEDSDTCYYAVAVAKKGTEFGFLDLRGKKSCHTGLGKSAGWNIPIGTLVTVGQIQWAGIEDRPVESAVSDFFNASCAPGANRDSQLCQLCMGDCSRSHNEPYYDYSGAFQCLKDGAGEVAFIKHLTVPAAEKASYELLCKDNTRAPIDSYKTCHLARVPAHAVVSRKDPRLANLIYSKLMAVTNFNLFSSDGYAAKNLMFKDSTQNLVQLPMTTDSFLYLGAEYMSTIRSLTKAQATGVTSRAIKWCAVGHKEKVKCDAWTINSFTDGDSRIECQDAPTVDECIKKIMRKEADAIAVDGGEVFTAGKCGLVPVMVEQYDEVRCSAPGEASSYFAVAVAKRGSGLTWTTLKGKRSCHTGLGRTAGWNIPMGLIHRRTMNCDFTTYFSKGCAPGFEVDSPFCAQCKGSGKSVGGDGSKCKASSEEQYYGYNGAFRCLVEDAGDVAFIKHTIVPEMTDGSGPVWAQNLMSSDFELLCQDGTTKPVTHFRECHLAKVPAHAVITRPESRGEVVSILLEQQARFGSSGSDSSFNMFKPDFGKNLLFKDSTKCLQEIPSGTKFQGFLGEEYMIAMQSLRECSNSTSDLEKACTFHSC
What is the function of this protein?
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
What are the official names of this protein?
Serotransferrin.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SBCC_STAAS
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEEVKKEKAQIENRYQQIDLLWQEIESFDDDNIKGLLGVATQQIDKLIENIPLLQARSKEILASVNESKETAIKEFEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEIEGIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKISFIDKTRVLFNDINKYQQSYLNIERLRTEGEQLGDELNDLIKGLETVEDSIGNNESDYEKIIELNNTITNINNEINIIKENEKAKAELDKLLGSKQELENQINEETSILKNLEIKLDRYDKTKLDLNDKESFISEIKSAVNIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIEDKLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDIDEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYELKKGKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVGGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: ENGB_ACTSZ
Sequence: MSEIKLNYHKTRFLTSAANIKQLPEDSGIEIAFAGRSNAGKSTALNALTNQKNLARTSKTPGRTQLINLFEVEPNCKLVDLPGYGYAAVPEQMKLQWQKSLGEYLQKRECLGGVVILMDIRHPLKALDQQMIEWAVSADLPLLLLLTKADKLSQSARSKTVKMVREAILPFQGDIQVETLSAQNKLGVDRLSAKLDAWFAPNFATE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HXB9A_DANRE
Sequence: MSISGTLSNYYVDSIISHEGEDPNASRFSNVQYSSARQPGPGEHPEFPSCSFQPKPPVFSSSWSPFSSHASNGLPAVYHPYIPTQPVPSTDTRYLRTWLDCAPRAEPLPGQGQVKMEPLLGHLGEPPKLVGQHEYILESSTAREINSGHSAGFEDNKDICEGSEDKEGPDQNDPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLTERQVKIWFQNRRMKMKKMNKDQPKE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B9a, Hox-B9.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UREF_ECOLX
Sequence: KLIPLGQSAGQNILFTLAERIPEVVAQSAIWPLDDIGSFTPAQIIASSRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_WOLPP
Sequence: MKLGVNIDHVATLRNARGASYPDPLKAAKIAINAGADFLTVHLREDRRHIRDEDVFNLKQNISTELNLEIAATEEMLKIAKEVKPYSICIVPEKREELTTEGGLNIVNMHSKLSGIIEEMHSFDIKVSLFIDPNINQLKYLEKLERKPDIIEIHTGDYCDNPSEEKLKLITNSAEYINNLGIECHAGHGINYKHAKEIKKIPHISALNIGHSLISEAIFHGLHSVTKKMKMTISK
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_BPSK1
Sequence: MAAYQTYTMAGIKEDFADWVSNISPEYTPLISMIRKFPVHNTMFQWQWDVLKDVDTENQHNEASDAKDVELTPTTVVQNYVQIMRKVVFVSDSANAVSSHGREKELFYQLKKAAKELKRDNEGIFLLKDRAGDAGSATKPRLTASFGSLIDASMKKTADLDEATLFEMTAKLYTEGADPTLIMYHPSNANFFASLQEKSGTRMRIFENDKRFVKQVEYIVDPLGQELKCIPNRWCPEDATYIFNPSDLGMAVLRAPKKVALAKSGSAEKYMIEQEVGFRLNNPKAAALIIGKYKEGGNGGGESVKS
What are the official names of this protein?
Major capsid protein, Virion protein G.
What are the subcellular locations of this protein?
Virion.
Protein: YAAI_ECOK1
Sequence: MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEEQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: VRTE_PENAE
Sequence: MFIAAVTHNWMERLAALSLLHYVLGAIFLLLLFHMLSNFFHPGLVDVPGPFAAKFTDLWRLFKVWQRRFKEDLPGLHASHRSTLIRIGPRMVSCSDPRAVELIYGFHTEFSKSDMVKAMAPIYKGKKQPTMFAAADNKTHARIRKPVAGAYAMTSIMQRMDELFIRPKRACDIHNWVQYFAFDMVLEMTMSRNLGFMKAGGDVDGVLKQLQKDLDYRGIALAMPIIDRIWRLNPVSKFFKPKQSGHFAMRCKRILEDRMAYEKSLDSRTQQQQDQKPHDFAHRFLEAQRKDPSISDGQLIGYMQANLIAGSDTTAVVMRTAIYYTLKQPWILQRLVTELDQYHGPLPVPFRIARFEMPFCGAIVREALRRHFAFIGMMERQTPPCGVVMPDGRRLPGGVVIGMHGDLIGRDRAIFGEDADEFNPLRWLARPGEPEAKYQERLRAMNAHDLAFGHGPRGCIGKHVAEMEIYKFIPTFFALIQPRFMRPEQSWTVRQLFVFKQSGMDMMLDWRQGKGLQSMA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system (PubMed:20534346).  The first step of the pathway is the production of the malonamoyl-CoA starter unit for the polyketide synthase vrtA (PubMed:20534346).  The aldolase vrtJ may be involved in the synthesis of the malonamate substrate for malonamoyl-CoA synthetase vrtB (PubMed:20534346).  The polyketide synthase vrtA then may utilize the malonamoyl-CoA starter unit, followed by sequential condensation of eight malonyl-CoA units to form the polyketide backbone (PubMed:20534346).  The cyclization of the last ring could be mediated by the lactamase-like protein vrtG (PubMed:20534346).  The proposed post-PKS tailoring steps are an hydroxylation at C5 catalyzed the cytochrome P450 monooxygenase vrtE, a hydroxylation at C12a catalyzed by VrtH and/or VrtI, and an O-methylation by the O-methyltransferase vrtF (PubMed:20534346, PubMed:24161266).  VrtC is then proposed to catalyze the transfer of a geranyl group synthesized by vrtD to the aromatic C ring of the tetracyclic polyketide intermediate of viridicatumtoxin to yield previridicatumtoxin (PubMed:20534346).  Finally, the cytochrome P450 monooxygenase vrtK catalyzes the spirocyclization of the geranyl moiety of previridicatumtoxin to afford viridicatumtoxin (PubMed:24161266).
What are the official names of this protein?
Cytochrome P450 monooxygenase vrtE, Viridicatumtoxin synthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNPH_RUEPO
Sequence: MRPSGRDLSEMRPVSIETGFTKHAEGSCLIKMGDTHVLCTATIEDRVPPFIKGSGLGWVTAEYGMLPRATNTRMRREAASGKQGGRTVEIQRLIGRALRAGVDRVALGERQITVDCDVIQADGGTRCASITGGWVALRLAVNKLMKAGDVISDPLVDPVAAVSCGIYAGQPVLDLDYPEDSEAGVDGNFIMTGSGKLIEVQMSAEGSVFNRAQLDQLLGLAEKGVGELVAAQMAATA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RECX_SERP5
Sequence: MNDLLSRAMRLLSQRDHSEAELRRKLAAQPFMAKARFGTKTPSSSAPLPEEPVDPAVIEQVIAYCYQHNWLDDQRFARSYIGSRSRKGYGAQRIRSELMQKGVDKELTQAALADCEIDWCEQAKQVAQRKFGDQLPTDWKEKAKVQRYLLYRGFFQEEIQSIYRDFAQ
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US453_GAHVG
Sequence: MLESEVSGNAPHSLWIVGAADICRIALECIPLPKRLLAIKVSGTWSGMPWAIPDNIQTLLTSTWEPKFDTPEDRAHFCDSDMVCVYKILGSPPNPLKPPEIEPPQMSSTPGRLFCCGKCCKKEDRDAIAIPVRYTATGKSRIQKKCRAGSH
What are the official names of this protein?
Uncharacterized 16.6 kDa protein.