PharMolix/UniProtQA huggingface dataset:
Protein: CHEB_ROSDO
Sequence: MHSDTNEHQSHVPAKKVLIVDDSRVIRMWLRTVLASDRRLEVVGEASDAVEARDYIRANPADVITLDIEMPGMSGLEFLTRLMRARPMPVVMLSSLTSKGSDAAVQALSRGAIDCILKPTDGYDLDLSRDICERVYQAACTRPASLKRGEATEKPADAPMMQRASALGQPCRRGSLILIGASTGGVSALEAVLPKLDPDGAPVVIVQHMPGNFLESFSQRLDRQLPQNVKLAEEGVPLRRGDVILAPGIGKHTEVVRRMDGWQCRFVANDPAALHCPSVDTLFLSAVSEAKKVSVAILTGLGKDGAQGMLKLAEAGATTFGQDEETSVVYGMPRVAFGLGAVQHQLPIHKIGEALRESKNASARTARRTTKVPLQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAT2_CYBFA
Sequence: MRSTSLLMQAKAAIPDIKQLPTKHKVSLAYTIHWPHKTVNPNINIKPREPVIFLHGVFGSKKNYRDYCQTIANQNYTPVYSLDFRNHGESEHAFPLVNYSTLTQDVVDFIHEHKLEKVDIVGYSLGAKVALLTLLKHPELCRSGVIIGNAPIKTPQVKVYLKAFIKALKALGDKRPEIKSNDKAWRAKARDVMRKYIPDGDILHYLLRNIDIRKPKNITEYKPGTINFSMPISHFDNKVVEDIADWPEEEVEGLKFEGPVRVIRGTQSVFINDKGLAAYQKHFPNYTLTNFNSNHLIWAERPLQVTKVVSDFLKKTRLLEMDGSAKALEESPKESYSRPPAHQQPLHKNDFTHIDVGALPVNGAQAESTQA
What is the function of this protein?
Probable alcohol acetyltransferase that uses acetyl-CoA to synthesize acetate esters from various alcohols (Probable).  Not involved in the synthesis of ethyl acetate (PubMed:28356220).
What are the official names of this protein?
Probable alcohol acetyltransferase, AAT.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RS16_ACICJ
Sequence: MSLKIRLARAGAKKRPFYHIVVADSRSPRDGKFIERIGTYNPMLPADHEDRIRLVTDRVTHWLSQGAQATDRVARFIGKAGLAPMPAFREQPVQSAPKKKAQERAAERAKAAEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: AROC_DESVV
Sequence: MSGNTLGRLFRLTTYGESHGAGLGGVIDGCPAGIALDEAVIQRELDLRRPGGNSASTTRQEPDRVRLLSGVFEGVTTGTPIAFHVENVDQRSRDYGEIARLYRPGHADFTYDAKFGVRDYRGGGRASGRETLSRVAGGAIAQALLARHGIAVRAFTVELGGVPADLVDVAGAQLRPFFSPDPDVVEAWEDMVRTVKGEGDTLGGIVQVEATGVPAGLGEPVFDKLDAVLAYALMSVGAVKGVEVGAGFEAARMHGSDNNDPIVPSGFFTNHAGGILGGISNGETIVLRAAVKPIPSIAQEQITIDRDGKPSALFIAGRHDISAIPRIVPVLKAMTALVLADMLLMQRRMATPQP
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CADE_BACSU
Sequence: MTSIHEDTHIGYAKLTIRSLERSLQFYCNVIGFQVLKKTDRQAELTADGKRVLLILEENPSAVVLPERSVTGLYHFAILLPDRKELGIALARLIEHGIAIGHGDHAVSEALYLSDPDGNGIEMYADRPRSTWQRDREGNYVMTTTAVDIEGLLEEAGDERKTSLPNDTIIGHIHLHVSDLKEAKAFYTDVLGFDIVGNYAGMSALFVSAGGYHHHIGLNIWAGRNAPPKPTNASGLDYYTVVLPHQEELDLVANRVKHAGYSIEETENSFRVKDPVSGAYITFVI
What is the function of this protein?
Involved in the meta cleavage of catechol to 2-hydroxymuconic semialdehyde.  Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol.
What are the official names of this protein?
Catechol-2,3-dioxygenase, Catechol-induced ring cleavage extradiol dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: RL25_POLNS
Sequence: MKVVAFERSVQGTSASRRLRNSGKTPGIVYGSKDPALVIELDHNALFHALRKEAFHSSILDLEIGGKTQKVLLRDYQMHPFKPLVLHIDFQRVSATKKVHMRVPLHFTNADTSAAVKLQGAVISHIATELEVSYLPADLPEFIEVDLAKIEVGHGIHAKDIALPKGVTLILHVEQENPVLANARIPAVKAAEPTDTPAAPAATAPAADATKVII
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NU4LM_MICSI
Sequence: MPSISININLAFATALLGMLMFRSHMMSSLLCLEGMMLSMFILSTLTILNMQFTMSFTMPILLLVFAACEAAIGLALLVMVSNNYGLDYIQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PROA_STRP2
Sequence: MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQMLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVAHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVAGDGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL50_DICDI
Sequence: MTLFSSISSISNPMTSSKSSISSFGSGTSIGSNSIACGGCGGGSGGILGSGLGIGLGLGLDLTGGSRTRGSCRGNGGSSNPVNGHGGMGGGNGSCCGI
What are the official names of this protein?
HssA/B-like protein 50.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: GLCNK_STRJI
Sequence: MTPNWSELVAAADPALVLPSGERRAEVAVPGPLRLDALLDLGEGHAVGVVRSADAARWTVPLVRDGAGGVRRSRPGDGTAEHLVAALARRGATPDAAFVLEAFTGAAPVTGERGIIVDQTNESVIVGECAVVKWAVRLPAEGEPGSPAAQRIAALARGGFTEMPRPWGLLTLAEGAQPVLLASVVAYLPGALDGWDWAVDDVRRLARGELTMDQALLPAAQLGTLTARMHAALAARGRTPATAADVAAWGVRMREELDEAVASVPGAEGERLKAWAPRIADVYAELDALAGTPLIDVHGDFHVGQILRADGRYAVVDFDGNPVLPADQRAARQPAALDVVGMTASLDHVGRVVVFRTPDVDPAPVRAWIAAAQRSFLDAYRTTLARLDADDLFDDRLLTPLRYAQEVREYLYAVRHLPHWVYVPDLSLTDLLPERLKD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of D-glucosamine (GlcN) to D-glucosamine 6-phosphate.  May be involved in the phosphorylation of acquired extracellular GlcN derived from the hydrolysis of chitosan, i. e. , in the incorporation of exogenous GlcN into the bacterial GlcNAc metabolism.  To a lesser extent, is also active on glucose, but is unable to phosphorylate maltose, 18 other sugars and several aminoglycoside antibiotics.
What are the official names of this protein?
Glucosamine kinase, GlcN kinase, GlcNK.
What is the protein family that this protein belongs to?
Belongs to the actinobacterial glucosamine kinase family.
Protein: HSP83_ORYSJ
Sequence: MASETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPELFIHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLKDDQLEYLEERRLKDLVKKHSEFISYPISLWTEKTTEKEISDDEDEEEKKDAEEGKVEDVDEEKEEKEKKKKKIKEVSHEWNVMNKQKPIWLRKPEEITKEEYAAFYKSLTNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTRKKQNNIKLYVRRVFIMDNCEELIPEWLSFVKGIVDSEDLPLNISREMLQQNKILKVIRKNLVKKCVELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSTNRTKIAELLRYHSTKSGDELTSLKDYVTRMKEGQSEIYYITGESKKAVENSPFLEKLKKKGYEVLYMVDAIDEYAVGQLKEFEGKKLVSATKEGLKLDESEDEKKRQEELKEKFEGLCKVIKEVLGDKVEKVVVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENAIMDELRKRADADKNDKSVKDLVMLLFETALLTSGFSLEDPNTFGTRIHRMLKLGLSIDEDESAEADADMPPLEDDAGESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
What are the official names of this protein?
Heat shock protein 81-3, HSP81-3, Gravity-specific protein GSC 381.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_ECO57
Sequence: MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_CLOK5
Sequence: MLNEAIKEVLSGKDLSESQSEQVMENIMNGQESSALIAGFLIALKMKGESIPEITGCAKAMRNMAVPVKLKSQYAIDTCGTGGDGGRTFNISTAAAIIAASAGVKVAKHGNRAVSSQSGSADVLKELGININLEKSKVEHCIDNVGMGFLFAPSYHSAMKNVAGIRRDLGVRTIFNILGPLTNPAFVKGQVMGVYDRKLLEPAAKTLLNLGCERAMVVHGGDGLDEITTTTVTYVCEVKDGEIRKYTLSPGDFGIKTTFYKNIAGGTARENAAIIMDILKGKTGPERDIVVLNSAAAIYIGKKAEDLKEGILRANELIDSGKAYAKYEEILNYNN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NADE_PSEAE
Sequence: MQQIQRDIAQALQVQPPFQSEADVQAQIARRIAFIQQCLKDSGLKTLVLGISGGVDSLTAGLLAQRAVEQLREQTGDQAYRFIAVRLPYQVQQDEADAQASLATIRADEEQTVNIGPSVKALAEQLEALEGLEPAKSDFVIGNIKARIRMVAQYAIAGARGGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLAKHQVRALARALGAPENLVEKIPTADLEDLRPGHPDEASHGVTYAEIDAFLHGQPLREEAARVIVDTYHKTQHKRELPKAP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: URED_ECOLX
Sequence: MSDFSGSGWLAEIFLRYELKRGVTRLTDKQHIGPLMVQRPFYPEQGIAHTYLLHPPGGVVGGDKLLINIDVQPHAHALLTTPGATKFYRSAGGVARQVQTLTVAPNGFLEWLPQENIFFPEAQVRLETHVRIASSSKFISWEIQCLGRPVLNEQFDNGDIRGRLQFYIDDKLTLAESIFIEGSQKQSAVMREFPMVGSLYIYPASDELKAELHESLAVFFSTEVRPLEYGLTDVDGILVLRLLGSQTEPMMACFAHIWQATRQYWLGYCPEPPRIWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_PSEE4
Sequence: MPTREIRHPLIRHKLGLMRRADISTKNFRELAQEVGALLTYEATQDLPLETYEIDGWCGKVQVEKIAGKKITVVPILRAGIGMLDGVLSLIPGAKVSAVGVARNEETLEAHTYLEKLAPDINQRLALIIDPMLATGGSMVATIDLLKKAGCKEIRAMVLVAAPEGIEVVEKAHPDVQIYTASIDQRLNEHGYIVPGLGDAGDKIFGTKQKDA
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RNB_SALEP
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIISADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPDNEGIAHQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIG1_YEAST
Sequence: MVAISMIWFFTKRMPRIFALAFNLISIFLLIFLLIGCYNPSNQSTFLVKYKFDDNSPFYTIIEKSYEKSNTTLGLEEVIIRSGYMGVCIDNIPSQYSSYNNMTTFSNSICYARKNLSSVPLYRDLEIQLSNIASSSSKTQSSVVLNILKLAQLTSVNVIHPYVLMATVILTILMFLFILYVTVPKLPFKLAVNKFLLLLSSTIVLTWGIGAMWTHVGINASYRLVPSSSMNIITVKKGKKAAVMAWFSFAFLLLDSVVLWLIFLRDRKSLKDEIDNVPCAQNRYNNYSSDSSTLHSKV
What is the function of this protein?
Required for efficient mating.
What are the official names of this protein?
Factor-induced gene 1 protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DENR_PONAB
Sequence: MAADISESSGADCNGDPRNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVVDDSIEDLGEVKK
What is the function of this protein?
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon.  Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Density-regulated protein, DRP.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: UP01_SOLLC
Sequence: YEDAYALQYCPR
What are the official names of this protein?
Unknown protein 1.
Protein: OTC_CUTAK
Sequence: MAFNLKNRHLLSLAHHSTEEIKFLVGLAADLKEAKYCGTEQPLLKGKNIALIFEKASTRTRCAFEVAAHDQGAHVTYLGPSGSHIGHKESMKDTARVLGRMYDGIEYRGFHQSVVEELAEYAGVPVFNGLTDEFHPTQMLADALTMREHAEKPFHEIKFAYVGDGRNNMGRSLLLLGAKLGMDVRIGAPEGLQPEAELVERCREWAEQSGGKVLVTASAEEAVRDVDFIHTDVWVSMGEPVESWSERVGTLLPFQINDALVKAAGNPRVKVMHCLPAFHNSETAVGAEVAKTYPELANGIEVTESVFESPACIAFDQAENRMHTIKAVLVSSLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PROMT
Sequence: MARVGVLLLNLGGPERIKDVGPFLYNLFSDPEIIRLPVRAFQKPLAWLISLLRSSKSQEAYRSIGGGSPLRRITEQQARELQSYLRNIGIDATTYVAMRYWHPFTESAVADMKADGVSEVVVLPLYPHFSISTSGSSFRELKRLKDGDDEFAELSIRCIRSWFDHPAYVSSMAELIKKQILACDLPQESHVFFTAHGVPKSYVEEAGDPYQDQIQNCSLLIIDQLENSLGFTNSFSLAYQSRVGPEEWLKPYTEEVLEKLGKSGVKELVVVPISFVSEHIETLQEIDIEYKEIAQKNGIVNFKRVPALDVYPLFIEGLADLVSSCLNGEGISLEEASKLPERVKLYPQEKWQWGWNNSSEVWNGRVAMIVFLSFLMELIIGGGPLHQIGLL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFBU_SALCH
Sequence: MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQMRELDREFGELTEETCRTIIDIMEMYHALHVSWANLKDTQAIDERRVTFLGFDAATEARYLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: STD1_YEAST
Sequence: MFVSPPPATARNQVLGKRKSKRHDENPKNVQPNADTEMTNSVPSIGFNSNLPHNNQEINTPNHYNLSSNSGNVRSNNNFVTTPPEYADRARIEIIKRLLPTAGTKPMEVNSNTAENANIQHINTPDSQSFVSDHSSSYESSIFSQPSTALTDITTGSSLIDTKTPKFVTEVTLEDALPKTFYDMYSPEVLMSDPANILYNGRPKFTKRELLDWDLNDIRSLLIVEQLRPEWGSQLPTVVTSGINLPQFRLQLLPLSSSDEFIIATLVNSDLYIEANLDRNFKLTSAKYTVASARKRHEEMTGSKEPIMRLSKPEWRNIIENYLLNVAVEAQCRYDFKQKRSEYKRWKLLNSNLKRPDMPPPSLIPHGFKIHDCTNSGSLLKKALMKNLQLKNYKNDAKTLGAGTQKNVVNKVSLTSEERAAIWFQCQTQVYQRLGLDWKPDGMS
What is the function of this protein?
Involved in modulation of glucose-regulated gene expression.  Together with MTH1, represses the hexose transporter (HXT) genes in conditions of low glucose.  Stimulates the SNF1 kinase by an interaction with the catalytic domain that antagonizes autoinhibition and promotes an active conformation of the kinase.
What are the official names of this protein?
Protein STD1, Glucose repression modulator MSN3, Suppressor of Tbp deletion protein 1, Suppressor of fluoride sensitivity 3.
What is the protein family that this protein belongs to?
To yeast MTH1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Nucleus.
Protein: RPPH_HELAH
Sequence: MLHKKYRPNVAAIIMSPNYPNTCEVFIAERVDIEGAWQFPQGGIDEGETPLEALYRELLEEIGTNEIEVLAQYPRWIAYDFPSNMEHNFYSFDGQKQRYFLVRLKHANSIDLNKHTPEFRTYQFIHLKDLLKKIVPFKRQVYRQVIAYFRREGYLGC
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RNAS2_MACFA
Sequence: MVPKLFTSQICLLLLLGLMGVEGSLHAKPGQFTWAQWFEIQHINMTSGQCTNAMQVINNYQRRCKNQNTFLLTTFADVVHVCGNPSMPCPSNTSLNNCHHSGVQVPLIHCNLTTPSRRISNCRYTQTTANKYYIVACNNSDPVRDPPQYPVVPVHLDRII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities.
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: MNMG_AZOSB
Sequence: MLYPTRFDVIVVGGGHAGTEAALAAARMGCRTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNASKGPAVRATRAQADRVLYKAAIRKRLENQPNLWLFQQAVDDLTVAGDRVTGVVTQIGLRFEAPAVVLTAGTFLNGLIHVGLEHYSAGRAGDPPAISLGQRLKELALPQGRLKTGTPPRLDARSIDFSVMTVQPGDDPVPVFSFLGSAAQHPAQLPCWMTHTNTRTHDVIRANLDRSPMYSGVIEGVGPRYCPSIEDKIHRFADKDSHNIFLEPEGLTTHEIYPNGISTSLPFDVQLEIVRSIRGLENAHILRPGYAIEYDYFDPRNLKSSLETKSIGGLFFAGQINGTTGYEEAAAQGLLAGANAALQVQGREAWCPRRDEAYLGVLVDDLITRGVSEPYRMFTSRAEYRLQLREDNADLRLTEKGRELGLVDDVRWAAFCAKREAIERETARLKTSLARPDLIPVADQERVLGKTLEREARYFELLRRPETTYASLMSLPGAPEQPETDPQVVEQLEIAAKYQGYIDRQQDEVAKQLQAESTRLPADLDYAEVRGLSKEVQQKLNLHKPETIGQAGRIQGITPAAISLLLVWLKRRDLAARSERRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG_SALEP
Sequence: MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_COXBU
Sequence: MPNVDDIRIFHGSANPSLAENVAKELNTTIGNALISRFSDGEIRFEIEENVRGRDIYLIQSTGHPTNEHVMELILMGDAFRRASAASITAVVPYFGYARQDRRVRSSRVPISAKVVADMMQKVGFSRLITVDLHADQIQGFFYMPVDNIYASITALEEYRLLDKLETPMIVSPDVGGVVRARAIAKRLNDSDLAIIDKRRPAPNQAEVMNVIGNVQNRHCVIVDDIVDTAGTLCHAASALKEKGALTVSSYCTHPVLSGNAVKNIMDSDIDELIVTDTIPLHEEAAKCRKITQISLSRLIAETISRINQKESVSSMFLD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM1_STAAW
Sequence: MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.