PharMolix/UniProtQA huggingface dataset:
Protein: ZBT7B_HUMAN
Sequence: MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFKKLFTEGGGGAVMGAGGSGTATGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPAVLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATASGVPNGEDSPPQVPLPPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEVPTVPAHPLTYEEEEVAGRVGSSGGSGPGDSYSPPTGTASPPEGPQSYEPYEGEEEEEELVYPPAYGLAQGGGPPLSPEELGSDEDAIDPDLMAYLSSLHQDNLAPGLDSQDKLVRKRRSQMPQECPVCHKIIHGAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYDLKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAASPAGLDLSNGHLDTFRLSLARFWEQSAPTGPPVSTPGPPDDDEEEGAPTTPQAEGAMESS
What is the function of this protein?
Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors.  Exerts distinct biological functions in the mammary epithelial cells and T cells in a tissue-specific manner.  Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment.  Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively.  Cross-antagonism between ZBTB7B and CBF complexes are determinative to CD4 versus CD8 cell fate decision.  Suppresses RUNX3 expression and imposes CD4+ lineage fate by inducing the SOCS suppressors of cytokine signaling.  induces, as a transcriptional activator, SOCS genes expression which represses RUNX3 expression and promotes the CD4+ lineage fate.  During CD4 lineage commitment, associates with multiple sites at the CD8 locus, acting as a negative regulator of the CD8 promoter and enhancers by epigenetic silencing through the recruitment of class II histone deacetylases, such as HDAC4 and HDAC5, to these loci.  Regulates the development of IL17-producing CD1d-restricted naural killer (NK) T cells.  Also functions as an important metabolic regulator in the lactating mammary glands.  Critical feed-forward regulator of insulin signaling in mammary gland lactation, directly regulates expression of insulin receptor substrate-1 (IRS-1) and insulin-induced Akt-mTOR-SREBP signaling (By similarity).  Transcriptional repressor of the collagen COL1A1 and COL1A2 genes.  May also function as a repressor of fibronectin and possibly other extracellular matrix genes (PubMed:9370309).  Potent driver of brown fat development, thermogenesis and cold-induced beige fat formation.  Recruits the brown fat lncRNA 1 (Blnc1):HNRNPU ribonucleoprotein complex to activate thermogenic gene expression in brown and beige adipocytes (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 7B, Krueppel-related zinc finger protein cKrox, hcKrox, T-helper-inducing POZ/Krueppel-like factor, Zinc finger and BTB domain-containing protein 15, Zinc finger protein 67 homolog, Zfp-67, Zinc finger protein 857B, Zinc finger protein Th-POK.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRHO_FRATO
Sequence: MSQIVVCAMYKFVTLEDFEAMRQPLLDTMIKNNVKGTLLLANEGINGTVAGTRESIDNLLAYLKADPRLVDIDYKESYHQEMPFYRSKVKLKKEIVTLGIDEIDPNKICGKYVEPKDWNDLISDPETVLIDTRNEYEIEIGTFKNAINPHTENFREFPQYVDENLDPKKHKKVAMFCTGGIRCEKSTALLKAKGFDEVYHLKGGILKYLEEVPKEKSMWQGECFVFDSRVAVNHDLEKGNYDQCFACRMPITEDDKKRPEYVKGISCHHCYDKVTEKQKARFAEREKQSQLAAEKGFSHVGDEAKKLAQLNKQKKQQAKEAARKKAQQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL31B_BURP6
Sequence: MKQGIHPDYREVVFQDMSNGFKFITRSTIQTRETIEFEGKTYPLAKIEVSSESHSFYTGQQKIMDTAGRVEKFKNKFGARASGKAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: ATPD_ECOL6
Sequence: MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLKALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS5_BIFAA
Sequence: MSDNEKETQVAEETQNTQAAAESNNEDRKSRRGQRGEGRRGERRNRREESHENEMLDRVVTINRVSKTHKGGRTFSFAALVVVGDGKGTVGVGYGKSREVPAAIAKGQLDAKKHMFTVPRIKGTVTHPVIGHDAAGTVLLRPAAPGTGVIAGGAVRAVMECAGITDVLTKSMGSATAVNVVRATVDALKKLEEPEEIAARRGMSLEEVAPDALLRARAEGIAEARKAREEAQAKAAQKDGE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CDA7_BOMMO
Sequence: MKLVFYAALLTAVLAKELQLATECDPEACKLPDCRCSSTSIPGGLEPRNTPQFVTLTFDDGVNVINVETYREVLYNRVNSNNCPVRATFYVSHEYTNYQLVNELYNRGHEIALHSISHRTPPSFWAAATYDEIKEEIADQKVQIAHFANIPFEEVKGVRLPFLQMNGNTSFQVMSDFGLTYDCTWPASAQTQRGLWPYTLDYASTQDCTIPPCPTASLPGSWVVPMIAWTDPNGFPCVMVDACTSFPDREDPDAWFRFIVTNFERHYLANRAPFGFFVHEWYISAYPAVKTALVSSSDVVEWVRNPIPIAEYRSRSCKTFRQTACPASSCGPLVAEHNQLSYWLQLCNRCPAKYPWVGNPFGLN
What is the function of this protein?
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin.
What are the official names of this protein?
Chitin deacetylase 7, BmCDA7.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 4 (CE4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOCD_SALTY
Sequence: MTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MSHA_ACTMD
Sequence: MKRVAVLSVHTSPLEQPGTGDAGGMNVYVVQTATAMARRGVEVEIFTRATSSELPPVAELAPGVKVRHVVAGPFSGLEKEELPGQLCAFTAGVLRAEARHEPGHYDVVHSHYWLSGQVGWLARERWGVPLVHTAHTLAKVKNLALADSDAPEPRMRVIGEEQVVAEADRLIANTDVEADQLTGLYAADPAKVLVVPPGVDLGRFTPGDRGEARRSLGLAPDALVLAFVGRIQPLKAPDVLVRATAALLERDPGLRSRLVVLVVGGPSGSGMRTPDELVGLARSLGVADVVRFLPPQGGGSLAQVYRAADAVAVPSHNESFGLVALEAQACGTPVVAAAVGGLPVAVRDGVTGLLVAGHRTSDWADALSRIALAPGLREALAGNAVGHARGFSWDRTTESLLAAYGQARDVFREEVYA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: OBG_VEREI
Sequence: MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPNGGDGGRGGHVFAVADPNLNTLVDFRYARRHEAKRGGHGMGSDMFGAAGADITLKMPVGTIITDAATGQPLYELLLPGEVITIARGGDGGFGNMRFKSAINRAPRHKTPGWPGEKKSLKLELKVLADVGLLGRPNAGKSTFIAAVSNARPKIADYPFTTLHPHLGVVRVAPEQSFVVADIPGLIEGASEGAGLGLQFLRHLQRTRLLLHIVDLAALDTGVDAQDAGVDPVAQAKAIINELKKYDRQLYDKPRWLVLNKLDMVPAGERQARVQDFVKRLKHQGPVFEISALTHEGCGPLVHAIFGHVQSGQRMDNEPPPLDPRFASAGPA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM3_ORYSI
Sequence: MDVNEEAMAAHKRAFLDFLDQDVGKGVYMQAVRDMVQNKRHRLIIGMDDLRNHSLDLARRVIRSPAEYMQPASDAVTEVARNLDPKFLKEGQRVLVGFSGPFGFHRVTPRDLMSSFIGTMVCVEGIVTKCSLVRPKVVKSVHYCPATGGTLSREYRDITSFVGLPTGSVYPTRDENGNLLVTEYGMCEYKDHQTLSMQEVPENSAPGQLPRTVDIIVEDDLVDSCKPGDRVSIVGVYKALPGKSKGSVSGVFRTVLIANNVSLMNKEANAPVYTREDLKRMKEISRRNDTFDLLGNSLAPSIYGHLWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAVMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADRGVVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVIAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDPEIDRQISEHVARMHRYCTDDGGARSLDKTGYAEEDDGDVNAAIFVKYDRMLHGQDRRRGKKSKQDRLTVKFLKKYIHYAKNLIQPRLTDEASDHIATSYAELRDGGANAKSGGGTLPITARTLETIIRLSTAHAKMKLRHEVLKTDVEAALQVLNFAIYHKELTEMEEREQREMEMKQQADHDAGASGGNADEHRSSGNDPMDVDVGNASNDQDVPAERIEAFEAILGQHVLANHLDQISIDEIEQTVNREAAAPYNRRQVEFILERMQDANRIMIRDGIVRII
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM3, Minichromosome maintenance protein 3.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_STRP2
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: COQ6_DANRE
Sequence: MLSLAKAKLAVVGIGRQCVAVRTLNGARAVHRSFSSSEHDQDSSTSENELFDIIISGGGMVGTAMACSLGLDPNLTGKKILLLEAGHEKKMDKIPETYSTRVSSISPGSATLLSGLGAWDHIVNMRCKPYNKMQVWDACSDALITFDKENLQDEMAYIVENDVIVAALTKQLQTLSDHVKVQYRTKVVKYTWPHPYHVSESIPWVQVALANGKTLHTKLLIGADGPNSMVRREAGIPTVKWNYDQSAVVAVLHLSEPTENNVAWQRFLPTGPIAMLPLSDTESSLVWSTSHQHAEELLQMDEESFVDAINSAFWSNENHSELVETAGSLFRMALSVLMPDSGSARQLPPSVSGIGPKSRVMFPLGMGHATEYIRHRVALIGDAAHRVHPLAGQGANLGFGDVSYLTQVLSQAAYNGKDIGAMQHLLEFETERQRHNLPMMTAIDLMKRLYSSNTAPMVLLRTFGLQATNAVPPLKEQIMAFASK
What is the function of this protein?
FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis.  Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid.  The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
What are the official names of this protein?
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, Coenzyme Q10 monooxygenase 6.
What is the protein family that this protein belongs to?
Belongs to the UbiH/COQ6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Golgi apparatus. Cell projection. Note=Localizes to cell processes and Golgi apparatus in podocytes.
Protein: M233_CONVE
Sequence: MMSKLGVVLTICLLPFPLTALPMDGDQPADLPALRTQDFEPERSPWFDPVKRCCSQDCRVCIPCCPY
What are the official names of this protein?
Conotoxin VnMMSK-03.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_NITMS
Sequence: MHKSVQDIVNMKKGKKKVSVITGYDYTLASLCDKAGIDVLLVGDSAGMVMLGYENTIPVTMDQMCMFTEAVSRARNNALLVADLPFMSYQASIEDAINNSGKLIKAGADAVKLEGGSIMAETISAIVDVGIPVMGHIGLQPQTTMLSQGYKVQGRTKDSAMQLIQDAKELEEAGVFSIALEMVSHEVAQIISETVSAPTIGIGSGVNCDGQVLVVQDLLGMYDKIKPKFAKRYMNLSEDIVKSLEDYKNDVESNTFPAEENWFSMDPEELKKLREQIGS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_THIDA
Sequence: MYAVIKTGGKQYRVSAGDKLKIEKLEAEVGSEITFDQVLMVGDGADIKMGAPLLRGATVSATVLNQARGDKIKIFKMRRRKHYRKSQGHRQYFTEVQIGGITA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ISPG_SHESR
Sequence: MYNETPIKRRPSTRIYVGNVPIGDGAPIAVQSMTNTKTTDVEATVAQIRALEKVGADIVRVSVPTMDAAEAFKVIKQSVSVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIRQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELERRLEDVTTAMDVSIIGCVVNGPGEALVSHIGLTGGHRKSGYYDEGERQKERFDNDNLVDSLEAKIRAKASQMANRIQVKDTTE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL35_RHIME
Sequence: MPKMKTKSSAKKRFKITATGKVRAAAAGKRHGMIKRSNKFIRDARGTMVLAEPDGKKVVKNYLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DF256_ARATH
Sequence: MKSSIFFKLLLLVSLLVVIFRQSYAVADYCNRDADCKRVCLRPYACNLTRHLCMCHPNDVSSSKQHCIPEHKGFGEGGPPPQRLKLYR
What are the official names of this protein?
Putative defensin-like protein 256.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFA_AROAE
Sequence: MHEYALLLLSTALVNNVVLVKFLGLCPAMGVSKSMDAALGMGLATTFVITLAAAASWMLEHWLLAPFDLGFLRILSFILVIAAAVQFTEMAIRKMSPALYQSLGIYLPLITTNCAVLGVALLNVQQGYGFFKSVLFGFGSALGFTLVLLIFAGLRERLALASVPAAFAGAPAAFITISLLSLAFMGLSGLVAT
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATP6_STAA9
Sequence: MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VIGLN_HUMAN
Sequence: MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEPSGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPKTLPWGPKR
What is the function of this protein?
Appears to play a role in cell sterol metabolism.  It may function to protect cells from over-accumulation of cholesterol.
What are the official names of this protein?
Vigilin, High density lipoprotein-binding protein, HDL-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS7_LATSS
Sequence: MPRKGYVAKRDVLPDPMYNSKLVSRLINRLMIDGKRGTASTILYDAFDIIKEETGNEPLEVFEEAMNNIMPVLEVKARRIGGSNYQVPIEVRPERRTTLGLRWLVSYARLRGEHTMDQRLAREIMDAANNTGAAVKKREDTHKMADANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TBATA_BOVIN
Sequence: MATEVRAQLAERSLPSPKGELKLEKKSGCQPRSHGDSGPQKELMIPGIVDFKLIREAVRTSKPQTPSAYRFGRLSHHSFFSRHHPQPQHVTHIQDLTGKPVCVVRDELSLPTISVPVGDPQSNRDPRLYSEAWKKELKDLASRVAIFTKESELKSKEKEEPQREQGAKYSAETGRLIPASTWAMARRHSHQGRNQPASRDEGDQTFVLQDQELLILELLSQILQTDSLNAIQFWLLYAPAKEKDMALGLLQTAVAQLLPQPLVPIPAEKLLNQLLEVQDSLQERHQLPYSQSPKKMKTPPLSKSEKPENIGKAQVLRVHSSQNPEEKAAKAEG
What is the function of this protein?
May play a role in spermatid differentiation.  Modulates thymic stromal cell proliferation and thymus function.
What are the official names of this protein?
Protein TBATA, Protein SPATIAL, Stromal protein associated with thymii and lymph node homolog, Thymus, brain and testes-associated protein.
What is the protein family that this protein belongs to?
Belongs to the TBATA family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TRMY_METAR
Sequence: MRRFVVVGHRAVTTPKFSLNDLPGGAGRMDIIARCVNASLFLSHDLRRDVEFFAILLGEPTPPVTIKFSGEHVRYLSPDERSPAALIKKALERGIPVEGEAEATPGVYISKRSFADLINGMDNLVYLHEDGEDIRSVELTGNETFVLSDHQNLTPEEEAVLEAKGAKKVSLGKKLYHADHCIVMVNWETDRR
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_RICRS
Sequence: MKLNELYNNIGAKKNKKRIARGIGSGKGKTGGRGIKGQKSRSGVAIKGFEGGQTPMIKRLPKRGFNCISTKKYNIINIYNIEEALADGRLSADDNITKEKLVEARVVNNKNNKKLVKLLSICSDDFAAPLSLKLDAYSAKAKDLIEKAGGKLL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TRPB_JANSC
Sequence: MPDDLLNSFMTGPDEKGRFGDFGGRFVSETLMPLILELEQQYEHAKTDDSFWAEMQDLWTHYVGRPSPLYFAKRLTERLGGAKIYLKRDELNHTGAHKINNVLGQIILARRMGKTRIIAETGAGQHGVATATVCAKFGLKCIVYMGATDVERQAPNVFRMKLLGAEVVPVTSGRGTLKDAMNDALRDWVTNVRDTFYCIGTVAGPHPYPAMVRDFQAIIGKETRDQMMAAEGRLPDTLIAAIGGGSNAMGLFFPFLDDKSVNIIGVEAGGHGVNEKMEHCASLTGGRPGVLHGNRTYLLQDEDGQILEGHSISAGLDYPGIGPEHAWLHEIGRAQYVSITDREALDAFQLSCETEGIIPALEPSHALAHVCKIAPDMPRDHLLVMNMCGRGDKDIFTVARALGWDMDGA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ACCA_IDILO
Sequence: MSLNFLDFEQPIAELEAQIEELKSVGNRGQLDLNLEEEVQRLTTKSQELTEKIFSDLGAWQVAQLARHPLRPYTLDYIRMIFTEFDEMAGDRSFANDEAIVGGIARLDGTPVMVIGQQKGRETKEKIRRNFGMPKPEGYRKALRLMQTAERFKMPIVTFIDTPGAYPGIGAEERGQSEAIARNLKVMARLTVPIVCTVIGEGGSGGALAIGVGDRVNMLQYSTYSVISPEGCASILWKSASKAPLAAEAMGVTAERSKELGLVDSVIPEPLGGAHRHQEEMAVRLKRQLIADLGSLQGLSHEELLDQRYRKLMSFGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_AGRVS
Sequence: MSNDPTHQFQIHKIVPIEIGGIDFSFTNASLFMVATVACAAGFLYFATSNRGLIPGRAQSVAEMSYEFVASMLREGAGSHGMKFFPMVFSLFMFVLTANLLGMMPYFFTITSQIVVTFALAIFVIGTVLVYGFYKHGLGFLNLFVPSGVPGALLLLVVPIEVISFLSRPISLSIRLFANMLAGHITLKVFAGFVASLGSLGALGVGGALLPLAMTVALTGLEFLVAFLQAYVFAVLTCMYLNDAIHPGGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.