PharMolix/UniProtQA huggingface dataset:
Protein: BR2D_PULPI
Sequence: GFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacterium S. aureus ATCC 25923 and the Gram-negative bacterium E. coli ATCC 25726.
What are the official names of this protein?
Brevinin-2PTd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: RNH3_LEUCK
Sequence: MQIVLQVSIPQLKKMAAYYAPYAVSKAPKGAVFVAKLSQATVTAYKSGKVLFQGSGFKVEAARWQDNANQPTQKMNASHVTPGATIPTDFANWSVIGSDEVGAGAYFGPLTTAAVFVSKNDLDWVKALGIADSKTLTDAKMRDIAPEIIQRLPHHVVNLLPEKYNALQPHNNVNQLKAISHNFALHKVLEKIAPITPDAILIDQFAQATTYFNYLSKAQQSPVIRQNVYFTTKGEQYHLSVAAASILARVVELDTMVALSHEAGMTLPIGAGKAVDLVAAKLIRQGQDLNHFAKLHFANTAKAKSLVN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_STRGC
Sequence: MENLKKMAGIKAAEFVTDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQIIAVTTSSVTSQQAEGLGIPLKSIDEVDLVDVTVDGADEVDPNFNGIKGGGGALLMEKVVATPTKSYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPAFRQKDGQRFVTDMKNFIIDLDLGVIENPIEFARELDHIVGIVEHGLFNQMVDKVIVAGKAGVQVLEANK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: Y252_WIGBR
Sequence: MDKKLLNIIACPICNKKLNFDLIRKELICEFDSVAFPIKDGIPILLRDSSYPIKKR
What are the official names of this protein?
UPF0434 protein WIGBR2520.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: LEPA_LISMO
Sequence: MNKEEMNARQKKIRNFSIIAHIDHGKSTLADRILEQTGALTHREMKNQLLDSMDLERERGITIKLNAVQLKYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVREEIEDVIGLDASDAVLASAKSGIGIEDILEQIVEKVPEPSGDVNKPLKALIFDSVFDAYRGVIANIRIMDGVVKAGDRIKMMSNGKEFEVTEVGVFSPKATPRDELLVGDVGYLTAAIKNVGDTRVGDTITLANNPAEEALDGYRKLNPMVYCGLYPIDSSKYNDLRDALEKLELNDSALQFEAETSQALGFGFRCGFLGLLHMEIIQERIEREFNIDLITTAPSVIYHVNLTDGSNIVVDNPAEMPEPGVIESVEEPYVKATVMVPNDYVGAVMELAQNKRGNFITMEYLDDIRVSIVYEIPLSEIVYDFFDQLKSSTKGYASFDYELIGYKASKLVKMDILLNAEKVDALSFIVHRDFAYERGKIIVEKLKELIPRQQFEVPIQAAIATKIVSRSTIKALRKNVLAKCYGGDVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAILKMDESK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VAL2_ARATH
Sequence: MESIKVCMNALCGAASTSGEWKKGWPMRSGDLASLCDKCGCAYEQSIFCEVFHAKESGWRECNSCDKRLHCGCIASRFMMELLENGGVTCISCAKKSGLISMNVSHESNGKDFPSFASAEHVGSVLERTNLKHLLHFQRIDPTHSSLQMKQEESLLPSSLDALRHKTERKELSAQPNLSISLGPTLMTSPFHDAAVDDRSKTNSIFQLAPRSRQLLPKPANSAPIAAGMEPSGSLVSQIHVARPPPEGRGKTQLLPRYWPRITDQELLQLSGQYPHLSNSKIIPLFEKVLSASDAGRIGRLVLPKACAEAYFPPISLPEGLPLKIQDIKGKEWVFQFRFWPNNNSRMYVLEGVTPCIQSMQLQAGDTVTFSRTEPEGKLVMGYRKATNSTATQMFKGSSEPNLNMFSNSLNPGCGDINWSKLEKSEDMAKDNLFLQSSLTSARKRVRNIGTKSKRLLIDSVDVLELKITWEEAQELLRPPQSTKPSIFTLENQDFEEYDEPPVFGKRTLFVSRQTGEQEQWVQCDACGKWRQLPVDILLPPKWSCSDNLLDPGRSSCSAPDELSPREQDTLVRQSKEFKRRRLASSNEKLNQSQDASALNSLGNAGITTTGEQGEITVAATTKHPRHRAGCSCIVCSQPPSGKGKHKPSCTCTVCEAVKRRFRTLMLRKRNKGEAGQASQQAQSQSECRDETEVESIPAVELAAGENIDLNSDPGASRVSMMRLLQAAAFPLEAYLKQKAISNTAGEQQSSDMVSTEHGSSSAAQETEKDTTNGAHDPVN
What is the function of this protein?
Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3.  Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings.  Plays an essential role in regulating the transition from seed maturation to seedling growth.  Functionally redundant with VAL1/HSI2.
What are the official names of this protein?
B3 domain-containing transcription repressor VAL2, Protein HIGH-LEVEL EXPRESSION OF SUGAR-INDUCIBLE-LIKE 1, Protein VP1/ABI3-LIKE 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YKTB_BACSU
Sequence: MTQMRFTEEDFNTFTIEGLDARMEVLKETVRPKLTALGEHFAPTLSALTGDEMFPHVAKHARRSVNPPADSWVAFANSKRGYKKLPHFQIGLWESHVFVWFAIIYESPIKEEYGKLLEVNQETITKNIPDSFVWSADHTKPGVHKQSEMDKEQLKTLFERLQTVKKAELLCGIQLQKEEVLNMNNQEFLQRIDDAFKQLAFLYRLTQKVTQA
What are the official names of this protein?
UPF0637 protein YktB.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: MUKE_HISS2
Sequence: MTDSIQDLLSIKLARAIANPLFPEVDSQLRSGKHIGQEYLDNYSFLADFQHELDSFYRRYNVELIRAPEGFFYLRPKATTLIARSVLSELEMLVGKVLCYLYLSPERLAQQGIFTVQEVHDELINLADETKLLKAINLRAGGSDLDKQKLAEKVRSAISRLRRLGMIHAVGDQHSGKFTISESVFRFGAEVRSGDDPLEAQLRLIREGEAATAQSLQEEKNGLKDNMDQSAVENEQYFENEENEGIA
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Probably acts via its interaction with MukB and MukF.
What are the official names of this protein?
Chromosome partition protein MukE.
What is the protein family that this protein belongs to?
Belongs to the MukE family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RK23_NICTO
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKSRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECR_CYTH3
Sequence: MNFPSKLLEDAVLEISKLPGIGKKTALRLVLHLLKKESKESESLANALLNARENIRYCKKCHTISDHELCAICTSNKRDKRVVCIVEDIRDVLAIENTNQYFGVYHVIGGVISPMERIGPDQLNINSLIERVITDTEIKEIILGLSPTMEGDTTAFFITKKLKSYPIKISTIARGIPFGGELEYMDEVTLGRSIATRTLFETKED
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MYG_HORSE
Sequence: MGLSDGEWQQVLNVWGKVEADIAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGTVVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISDAIIHVLHSKHPGDFGADAQGAMTKALELFRNDIAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GRP_RAT
Sequence: MRGSELSLLLLALVLCQAPRGPAAPVSTGAGGGTVLAKMYPRGSHWAVGHLMGKKSTDELPPLYAADRDGLKEQLRGYIRWEEAARNLLGLLEAAGNRSHQPPQDQPLGSLQPTWDPEDGSYFSDAQNAKLVDSLLQVLKGKEGTAS
What is the function of this protein?
Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex.
Protein: PRMC_THEMA
Sequence: MDTRKNVSGAERKIWSLIRDCSGKLEGVTETSVLEVLLIVSRVLGIRKEDLFLKDLGVSPTEEKRILELVEKRASGYPLHYILGEKEFMGLSFLVEEGVFVPRPETEELVELALELIRKYGIKTVADIGTGSGAIGVSVAKFSDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEFLEPFKEKFASIEMILSNPPYVKSSAHLPKDVLFEPPEALFGGEDGLDFYREFFGRYDTSGKIVLMEIGEDQVEELKKIVSDTVFLKDSAGKYRFLLLNRRSS
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: DHAL2_LISIN
Sequence: MSELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELLTVSPDIATLLKKSGMILLGKVGGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAAAVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNADPIETFSAFVDAMHAGAQSTIPLIAKKGRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV
What is the function of this protein?
ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone.  DhaL-ADP is converted to DhaL-ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone binds to DhaK.
What are the official names of this protein?
PEP-dependent dihydroxyacetone kinase 2, ADP-binding subunit DhaL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVAL2_HUMAN
Sequence: MKSLRVLLVILWLQLSWVWSQQKEVEQNSGPLSVPEGAIASLNCTYSDRGSQSFFWYRQYSGKSPELIMFIYSNGDKEDGRFTAQLNKASQYVSLLIRDSQPSDSATYLCAVN
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 12-2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GCSP_DEIRA
Sequence: MTKSLSDLLQTNDFTRRHIGPSEAEQAEMLGVLGVSSLDELTQTTLPAAIQFDGELHTGPGMTEAQALAELKAVAQKNKVFRSYIGMGYAGTDVPPVILRNMLENPGWYTAYTPYQAEISQGRLEMLLNFQQTVQDMTGMPVSNASLLDEATAAAEAMTLAKRQSKNKGSNVFFVADNVHPQTMDVVKTRAEYFGFEVQTGSADAIPEGAFGALVQYPGTHGEVLNLAPIAEKAHTQGAALIVATDLLACALLTPPGEQGADIVVGSAQRFGVPMGFGGPHAAFLACQKGFERSMPGRVIGVSKDVRGNTALRMAMQTREQHIRREKATSNICTAQALLANMAAAYAVWHGPEGIKTIAERVHRLTGILAKALQDAGIKANETFFDTLTFEGQDDLGARAEAKGINFRLDGGKVGISLDETVTPQDLADIIEVVTGKGVDVQKLDAEAVDGIPAPLKRQSDFLTHPVFNTHHSEHGMLRYLKQLENKDYSLTHGMIPLGSCTMKLNATTEMIPVTWPEFGGLHPFAPESQTQGYAEMLAELERWLADITGYDAVSMQPNSGAQGEYAGLLVIRKYHEARGEAHRNICLIPASAHGTNPASAAMMGMQVVVVKTDEQGNIDFDDLKAQAEAHSDHLAALMITYPSTHGVYEENVRDVCDLIHQHGGQVYLDGANMNAMVGVAKPGLIGGDVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPFLPNHAVAPTSDSHTGAVSAAPYGSASILPISYLYIKLLGAAGLRQSTQVALLNANYIAKRLSGAFPVLYSGKGGRVAHECILDIRPLKQESGVSEEDIAKRLMDYGFHAPTMSFPVPGTLMIEPTESEPKAELDRFVDAMLNIRREIQDVQDGTISAADSPLKHAPHTLKDLMDSEWTRAYSRETGAFPSAAQKAWKYWPAVNRVDNVYGDRNFVCSCPPIEDYIGA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: USHA_ECOLI
Sequence: MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ
What is the function of this protein?
Degradation of external UDP-glucose to uridine monophosphate and glucose-1-phosphate, which can then be used by the cell.
What are the official names of this protein?
Protein UshA.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Periplasm. Note=Exported from the cell, except a small proportion that is internally localized.
Protein: SELU_MARN8
Sequence: MASRPDTDDYLNLFLNDVPLMDVRAPVEFAKGSFPSAENAPLMNDEERHRVGICYKEKGQDKAIELGHQLVSGDIKAQRIEAWKRFVAQHPEGYLFCFRGGLRSRLTQQWIRDSGIDYPLVKGGYKALRRFLIDSLEAQIESGQFRILSGRTGTGKTRVLMQLPNPVDLEGLANHRGSSFGRQVTPQPSQIDFENRLGVAMLKARHQAGGPIYLEDESRLIGRCALPETLRARMSESPLLILEQAMEERIAIIRADYVEGMLASYRARDGEDAGWLNFRDYLLSAIDRIRKRLGGERYQKLRNLMLQALDQQEANGSLEGHHGWIEALLTDYYDPMYDYQLTQKQGEILVRGGPEVITEWARSRTST
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: SYP_VIBPA
Sequence: MRTSNYLLSTLKETPNDAEVVSHQLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAVETLMPVVQPFELWEETGRSEKMGPELLRFTDRHVRPFVLSPTAEEVITSLVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDIDKAGLEKSYQAMHDAYCKAFDRMGLEYRPVLADSGAIGGSGSQEFHVLADSGEDLIAFSTESDYAANIEKAEALAPAVERAEPTQEMTLVDTPNAKTIAELVEQHGLPIEKTVKTLFVKASDEIDAPIIALIVRGDHELNEVKAENLPQVASPLEMASEEEIRELIGAGPGSLGPVGLELPFIVDRSVAVMSDFGAGANIDGKHYFGINWGRDVELGQVEDLRNVVEGDPSPCGKGTLMLKRGIEVGHIFQLGNVYSEAMNCSVLGPDGKNVILEMGCYGIGVSRVVASAIEQNHDKYGIIWPDAIAPFQVAIVPMNMHKSERVKEAAEKLYAELTAMGIEVLFDDRKERPGVMFSDIELIGIPHTIVIGDRSMDEGNFEYKNRRTGEKTPVAMADIVEHVKSQLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_ACTP7
Sequence: MHLTSREQEKLMLFLAGELAAKRKARGVKLNYPEAIAYIASHLQEAARDGMSVAEVMQYGATLLTVDDVMEGIAEMVHEVQIEATFPDGTKLVTVHNPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_LACLS
Sequence: MKTLQAKLSNKKNNFVPYIMAGDHERGLEGLNETIQLLEQAGSSAIEIGVPFSDPVADGPVIEQAGLRALAKNVSLSKILDSLKSIETEVPLVIMTYFNPVYQFGIENFVAALENTAVKGLIIPDLPKEHEAYIKPFITDKDICLVPLVSLTTPISRQKELVVDAEGFIYAVAINGVTGKENAYSNQLDHHLETLSKLTDIPVLTGFGISTLTDVERFNKVSAGVIVGSKIVRDLHENKESDVIKFIKNAINF
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NANK_YERPS
Sequence: MGKGLALDIGGTKIAAAVVTESGMLIGRQQIATPRGGAGQLAAALETLIAPYRHQVDFIAVASTGIISGGRLTALNPANLGGLADFPLYDCIRSISDLPCVLLNDGQAAAWAEYQALGDKNDNMMFVTVSTGVGGGIILNKKLLVGQRGLAGHIGHTLSDPHGVLCGCGRRGCVESVASGTAIGAETLGWKQPVSAATVFDMAQQGDAQAGKVINRSAAAIAQMLADMKMALDLEVVILGGSVGLAVGYLERVVAAQKTLPGIYRVPVQEAHHRQDSGLLGAALWARTSL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: NRA4_CAEEL
Sequence: MGSLPLILLSLLLPGALANVYSCAGSVKSTSPVDYSQLKLQVRLLTLEGHMKHEEEVNPSNGYFMIPVYNKGHYTLKVSAPAGYYFEPDSIEIKIDGKTDACSLNEDLVFHLTGFSVRGTVDGAAAGLPLVLTENGKQIAETKTEDGGKYEMRAPPGKYEVSTGAGASECISKGKTSVEVKNAPVVVTPNFKISGYQLEVHTRTESMNPFVDAVMTLYATSSIDLPNIKCVGSEGSLNVPSTHNVKCSIGKTDPRGRLSVACVPSGEYYLAASHVNGPKSINFSPNPQKVVVSQAASEARFVAQSATGRVRVTSKDLPLSGVEVLVNEKSGGKTDSQGYLKIENLKEDEHTTITAKAPNTQFSTVHANVKFPKVEIQDVTVQKFDICGQVEKSENGVLGKLTFTRKDDKRSLEIQPKADGSFCQPVSPGLFTIEPTDKTSSLTPRLLEVEVLKNAVTNLRFTHFKTNANVHLSCIGACPTATVSLFLPGQTLVRSVKGTDVFTFENIGPGTYSARLDDNGRGCWEKSEMTLVVEQSNTQPTIHFKQNGFAAQIEISHPAEIEWSNADKKQLNGKTSTKGGEVISICVPTSGVYDVSLGSCYKFERQQFKLTVPFDGVHKEKAVAARISGTIDLENDKNAAVSIRIKSSAGDREIQVPALDNGRFTFEEPLASSGEQLVIVPSSKLRLFEPTSKSVTVTGKCIENAVKFNSFRGIFLDGSIKPAVEKAVVKAVLKKDKDVVIEAISNKDGAFKIGPVKRVEDYDITATLDGFKFTPTSTPGHFQSVKLSQLSIKVVDEVTNAPLDGVLLSLVGGKGAGSDYRSNNVLDETAHKNYVALAPGEYFVRAILQEYKFSPSTSTIVVKEGQHENVVLKGKRVSFSAYGKMREMSGDAMKDVIIEALSEGCDLHQSEATTKEDGTYRIRGLLPDCEYQVHAKSYADGSPAPHSFPRSFTVSMTAEDVKGLEFMATITAKTTDIAVEIGMDTLPEIQSVRVVITKNNNDHVQVASVVAPQHLHYLVNLPRDGVEYAIRVEAEKPPQAFAAKTVRVVADQAMKVARVPLTSSKRANDVDISVGTFLSLPFFVTLALVFFNQNRVLELLGTFIDWARNTFAPTADNHHRKRK
What is the function of this protein?
Involved in the recognition and selection of protein complexes to exit the endoplasmic reticulum (ER) (PubMed:19609303).  In muscles, regulates levamisole-sensitive nicotinic acetylcholine receptor (L-AChR) subunit composition, possibly by allowing only specific L-AChR subunit combinations to exit the ER (PubMed:19609303).  Specifically, may promote the inclusion of alpha subunit unc-38 into and the exclusion of unc-29 from L-AChR (PubMed:19609303).  Regulates L-AChR sensitivity to agonists such as nicotine and levamisole at neuro-muscular junctions (PubMed:19609303).
What are the official names of this protein?
Nicotinic receptor-associated protein 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PDE6C_MOUSE
Sequence: MGEISQEAVERYLEKNPCFAKEYFDKKLRVEALGVIFKNSHAGVQTGLSLPEMTQVEESAVCLELLQCMQDEAGSAEQMAHRALQRLAQLLQADCCSMFSCRARNGIPEVASRLLNVTPTSKFEDNLVAPDREVVFPLDIGIVGWVAHVKKALNVSDVKKNSHFSDFMDKQTGYVTRNLLAVPIVAGKEVLAVVMAVNKISAPEFSKQDEEVFSKYLSFVAVALRLQHTSYLYSVESRRSQILMWSANKVFEELTDVERQFHKALYTIRTYLNCDRYSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREIIFYKIIDYILHGKEEINVIPSPPADHWTLVSGLPTYVAENGFICNMLNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEHITETLTQFLGWSLLNTDTYERVNKLESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVEVIEECEERQLLAILKEDLPDPRTADLYEFCFSDFPITEHELVKCGLRLFLEINVVEKFKVPVEVLTRWMYTVRKGYRPVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMKSTSPLARLHGTSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLALYFKKRTMFQKIVDTCEQMQSEEETIKYVTSDPTKKEVIMAMMMTACDLSAITKPWEVQSQVALLVANEFWEQGDLERTVLQQQPIPMMDRSKKDELPKLQVGFIDFVCTFVYKEFSRFHGEITPMLNGLQNNRVEWKSLAEEYEAKVKVTEEEAGKQEEEASDGKAATDLGGSAEDKKSKTCLML
What is the function of this protein?
As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.
What are the official names of this protein?
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: HXA4_MOUSE
Sequence: MTMSSFLINSNYIEPKFPPFEEFAPHGGPGGGDGAVGGGPGYPRPQSAPHLPAPNPHAARQPPAYYAPRAREPSYPGGLYPAPAAACPYACRGASPGRPEQSPAPGAHPSPAPQPPVPLGHCAPGPTTPAVATGGSAPACPLLLADQGPAGPKGKEPVVYPWMKKIHVSAVNSSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNTASAPAGPPGKAQTHSPHHHPHPLPGASTPIPSSI
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Binds to sites in the 5'-flanking sequence of its coding region with various affinities.  The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.
What are the official names of this protein?
Homeobox protein Hox-A4, Homeobox protein Hox-1.4, Homeobox protein MH-3.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.