PharMolix/UniProtQA huggingface dataset:
Protein: ACTC_XENTR
Sequence: MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility.
What are the official names of this protein?
Actin, alpha cardiac muscle 1, Actin alpha 1, Alpha-cardiac actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNH2_LISW6
Sequence: MSESISVIREKLSHVISEQDAFFQLCLQDERKGVIKLIESTRKKLEKEAQLIAKLAEMKQYETNLSTQGFQYIAGVDEVGRGPLAGPVVAAAVILPADFSLLGINDSKQLSEAKRDMLFEIIKKEALSIGVGIIEHDMIDQVNIYEATKLAMSEALDQLNPAPDFILVDAMPLKYSESELSLIKGDTKSISIAAASIIAKVTRDRMMQHYDALYPGYDFANNMGYGTKKHLNGLDTIGVCPIHRLSFSPVKEAKLHFESLK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_RICTY
Sequence: MLKYGVIIIGGGHAGVEAAAASARLGVHTLLITLKPENLGEMSCNPAIGGIAKGTLVKEIDALDGLMGFVIDKAGIHYKMLNETRGPAVWGPRAQADRKLYKKVMYQILTNYRNLDILYGKVEDIQIKSSKVEAVILNNGIKIFCQKVVLTTGTFLSGFIHIGSMKIPAGRIYEEPSYGLSNTLKRLGFKIARLKTGTPPRIDGRTIDYSKTTLQQGDQIPRPFSELTDAIDVPQINCFITKTTAETHDIIRENLDKSAMYSGQIKGIGPRYCPSIEDKIVKFSTKLEHRIFLEPEGLEDYTIYPNGISTSLPKEIQYKLIKTIPGLENAQVLRPGYAIEYDYVDPREINITLETKKITGLYFAGQINGTTGYEEAAGQGIIAGINAALSVKDQEPFILTRATSYIGVMIDDLTTSGTVEPYRMFTSRSEYRLSLRADNADLRLTELGINIGVVTEKRKNIFTKKCNNIEKTKLLLNKLSLTTSKLAKIGIQVAQDGKYKTVLDLFKIPTFNVEQAIKIFPILRKQNNNILQLLYIEAKYASYLTRQYADINLFQSEEIQLIPKNIDYFKIPSISLEIQEKLSYHKPTTIGVARRISGITPAAIMAIIIYLKTKYSDGSSK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_AZOPC
Sequence: MAFRKENKVKSFTRIFISLASSDNILAQSSGEVLKPETINYRTYRPERDGLFCERIFGPIKDYECHCGKYKRIRYKGVVCDRCGVEVTEKRVRRERMGHIQLVVPVVHIWYFRSLPNKIGYLLGLSSKKLDAIIYYERFVVIQPGITDKKVCDLLSEEEYLEVLDGLPVENQRLDDINPDKFIAKMGGEAIYDLLSRLELDSLSYELRHKIDNDTSQQRKIDALKRLQVIESFRSSKNKNRPEWMVIGVIPVIPPELRPLIPLDGGRFAASDVNDLYRRVIIRNNRLKRLIDIDAPDVILRNEKRMLQEAVDSLFDNSRKSSAVKTDANRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKMHECGLPKGIAAELYKPFIIRKLMDRGVVKTVKSAKKLVDGRDPIIWDILEYVMKGHPVLLNRAPTLHRLSIQAFQPKLIEGKAIQLHPLSCTAFNADFDGDQMAVHLPLGNEAILEAQMLMLASHNILNPANGTPITIPSQDMVLGLFYITKMRRGAKGEGLKFYGTEEAIIAYNEGKVDIHAFVKVYVDDIDENGTPINHIIETSVGRVIVNGFVPKAVGFVNEELSKKSLRSVISDVIKTCGVSRTAQFLDDIKDLGYMMAFKGCLSFNLDNVIVPKEKETFVQEGYKEIEEILANYNMGIITYNERYNQIIDTWTHVNSRLSDALMKQLREDDQGFNPVFMMLESGARGSKEQIRQLSGMRGLMAKPQKSVMGGGQIIENPILSNFKEGLSVLEYFISTHGARKGLADTALKTADAGYLTRRLVDVSHNVIINEEDCGTLRGLIATELRKNEDVVVSLYERILGRVSVCDVQHPESRKIIVYAGEEISEDKALAIQNSSIERVEIRSVLTCESKKGVCVKCYGRNLATGSIVQIGEAVGVIAAQSIGEPGTQLTLRTFHVGGIASNIATESSVVSKYDGILEIDELRTVEVVDEINNRHLIVVSRLAEMRIIDTRTKIVLATYNIPYASKLFFNDRDEIKKGDLLFEWDAFNASIVSEVAGRFHLENVIENITYKNEYDEQTGLKEKVIIESRDKTKIPVIHILDENGEIRRIYNLPLGAHITKEEKDVIRVGEVLVKIPRTVGKTGDITGGLPRVTELFEARNPSNPAVVSEIDGEISFGKVKRGSREVIVTSKNGDYRTYLVSLSKQILVQENDYIRAGMPLSDGIIAPSDILAVNGPTAVQEYIVNEIQDVYRLQGVKINDKHFEVIVRQMMRKVEIIEAGDTKFVARQLVDRDEVSEENDHIWDKKVVVNVGDSSNVKQGQIITMRKLREENSILKRRDLRLIEVRDSIPATVMQILQGITRASLQTSSFISAASFQETAKVLNEAAIKGKVDKLVGMKENVICGRLIPAGTGLKEYDKIMVETTME
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: COAD_BRASB
Sequence: MQRIALYPGSFDPVTNGHLDVVRQAVHLCDRLIVAVGVHHGKKPLFSTEERLAMVHEVLEPVAAAAGCGFEASTYDDLTVTAAQKAGAIMMIRGLRDGTDFDYEMQLAGMNQTMVPGIQTVFVPASVAVRPIAATLVRQIAAMGGDVSHFVPAAVAASLKAKFN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_LEPCP
Sequence: MIGEWNYGTGRRKSSVARVFIKKGTGKIIVNGKTVEEYFGRQTSIMICKQPLFLTNNAEAFDIKVNVHGGGESGQAGAVRHGVTRALIDYDAALKPELSNAGFVTRDAREVERKKVGLHGARRRKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: FGF3_HUMAN
Sequence: MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Required for normal ear development.
What are the official names of this protein?
Fibroblast growth factor 3, FGF-3, Heparin-binding growth factor 3, HBGF-3, Proto-oncogene Int-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: HOB2_YEAST
Sequence: MSMLPWSQIRDVSKLLLGFMLFIISIQKIASILMSWILMLRHSTIRKISFGYFFGTSIRRAFILTDFAQIYIGKITLRIGWKPGIVFHNVDLKLFGKDSHITAHSTKDSRTYFNPRDQTFTFVINRRVLSILKLVFSFSTFFHTLALTVPNGKQYKLNIGSITISHPHDDTIKLEAFLHDFTHPETKDTLNHTGFFMVCKIGKEDDTGSNCTKVILKNWKSSLKISDVCWHLPEKKGKNLHSEPVEPFSAGDDAEMLTSYRKMLKPFHYPLKTLNILDLKVENVKLIYKKKFTIRISSAQLYLESISILNNVSALELLPLNKPTWGDFELSLSANAVVVDIDGNTAVRIPFGNVILTSDILLFLLDNVPLRRTKVSSILNIINPSVFLTIHQVLEVLHLVDKFDSPETSSCTNTNDRSLNILDLDIDRLPSFNFELLMSNFISRLHISDEENVTFKVFSTHALFSRNNLSMTPKKGQVMQIRPDWPFAKTALVSDQLSNYIKIVGTSLSYLRIPTEQDANPVSIPVCGFERLDTFLDEFSNSKLIVQSTLRHSYVSLENIEVLHTLSRAFDKIYLLISSRTKRNAAHKANGGKLGDLNEAKKTFNWSLKLRMKDISCSLLVAGFLPKNLDPVEAENFNLSDVTRGAKVVFTESILLADSQEKNFTIIDASVYRFMDGTTYKPSPEVIIQFTNLLLSFNDSDEIHFSLPKIKFKMDVNIIWLWFYIRSIWIKFRPNSKLSRNSVSSVKSVNVLDRLRVDIGKMIIELTLPHNTEVLLIFERIGLSSSTKNLTIASLSAYVVSVYVKHIKVYVSLLNINDFELDTEELICKKSAVINTSLIHFHAEYHFRFYMITDNIVTLYKSFKQIKLAFSNLNEFKRLYPQQQFPKKVPNLHICCQDFLIDIEEDPFEQELGLILKVGVLEQRERLKKLEEFKEKLSTYEDMNVRLRSLYDTSRGQSFFPEFYANDQEYEQKAYLRLLENFSTSWIARYRKAKLSFYGMPYRVISREELGTKYHLFTRQKTSTVANLVVKDLDFKLGSPSFPLDNYMDFVYQYGKKVPKSTEYTLLIILGLKIKSALWELRLRDYPIPAISFPDTFTTGDVVFAEKMPAPCALHTVYVPFVSSAQRSPYNDANTIYGLHIIRTINSVKTYFNIRSMVTSSSSARITWGKSLQPGYESLMLWFDFLTKPLIDPSKKLGFWDKFRYLVHGKWIYEFSEESEIHLNIKGSHDPYKITDDGAGLAFCWSGGTTIYVHNSTDPKEFLKIESQRFQLAVPDFAKVSKFDKVFMKLDGRVIWTLGLLFEQGDISKAGDEERFLPNRPHYEIQLMNPDGVADLDHHDTYKGFRTSFIHMSFGVYSSEHGSINSLYLAPYALTHFFKWWNLFHTYTSGPIRQGRLFTDVLQNKTKFGRSLFTIAYQLHLKRLMVTHIYRHITTQYDLEKDRKITFTGLKGRFDSLKIDLHQKRVKLTHTNQKLNKSKPVWKFKMSRGEIDCAEADIRILSTLFDQEAVKEILTSGLDGILEDEPSRPITPQDVEYLRESDWYDYEDYIDLNQVPLGSSLPLKLEAIPLLYSPRISYFRKINDDGYVLAYPFGTEESHNCLIGKNHPELTQEKLATERKREIEEQLKLLHITLSELQSNKGGGSVSGNSERYARELKAEVAELNHRLHTVNTILSDLKISETIPGGNTDGDSSSSLSDTDVNLENAPPIQNRISLLRTNTVESFVSMRKASTMQVESTYDNRFMVHNIELKIDNKIRHHLLEYASSAFERKSMRFAVTYKSVTILKELLGNVLTGVRTSVEDYGSILEDDLASNSEFIEHFEKLIREVPSDDFDYVDNYLFRLISPQVQIKSDVERNAAVILAARDIEMGIIDIVQVYGKSGKRIPVDVDTIVETRYSAVSKDIQLFTLFKKDLEGPEGRFFHKNGYGSDKESDIWPPWIPLEMCFDGSLLDKHVFLKRRSMFLTYVAPNPLFFSANDTSAFSYDSRFRIAFPGLVLTSDCQQYCAVYAIAEDLLSFGSSLDEKVEKLSRILFTDEVRNNLENLDVSVVTALQERIKELYYTRAYLKLHEPRLFMKSGQELTFDIQTSTLKLTLLMTAIKKTYDRMGSGNRVIQKRLRWQVGTDELIWELYDESKTPFVTIGLGPSTFIRSETSDGTNSNKVSISSLQCFNQQENPVYTELLAPFYENSSYNKNAPMVEIFWILGPSVGGISDLQDLIVSLQPLIFKMDHKTSEKLMNYLFPKIEQTSIEPNSPELVPRSSTSSFFSSSPVLRHSLSNGSLSVYDAKDVDSWDLRSIQSKEGIKKHKGDHRKLSASLFVQPDYNINEMVKRSGTFFNVKSIIIRKTLMSVCYKGSHSLLTDVNNLIVRVPVLKYHNKLWSREEFFTALKRDVVRIVLQHLGNIIGNKFLPHKKENKKKTSMEIHRLLSPDSQNRDNSHILEVEGHNSFYSSTHSSDIRSINSDETYNENDGNGVKPFYPVTSEFSKNK
What is the function of this protein?
Tube-forming lipid transport protein which may bind to phosphatidylinositols and may affect phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) distribution.
What are the official names of this protein?
Protein YPR117W, Bridge-like lipid transfer protein family member 2B, BLTP2B, Protein hobbit 2, HOB2.
Protein: SYGA_OENOB
Sequence: MTKKMSMQDIILNLQEYWAEQGANLMQAYDNEVGAGTQSPYTFLRANGPEPWNAAYVQPSRRPADGRYGHNPNRLFQHHQFQVVMKPSPENIQELYLGSLTRLGLKASEHDIRFVEDNWENPSMGAAGIGWEVWLDGMEVTQFTYFQQVGSIEVDSVTAEITYGLERLASYIQDVLSVYDLEWGNGVMYGDIFKEPEYEHSVYSFDQSDEKMLLENFDQYEAEAKRLTKLGLVHPAYDYILKLSHIFNLLDARGAVSVTERAGYMHRIRSMARAIAREFITARAKLGFPLLKDSKLREKYIGEKGIYTKKLAKKIKKEA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_RHILO
Sequence: MSKRIAGPEIERLIQLLAKVPGLGPRSARRAALHLIKKKEQLLSPLAAAMSEAADKVRICSTCGNVDTADPCMICTDPRRDAGTIIVVEDVSDLWALERAAAMNVRYHVLGGTLSPLDGIGPDQLNIRSLIDRVAGGEVKEIILAVNATVEGQTTAHYLTDQLSGFDIKVTRLAHGVPVGGELDYLDEGTLAAALRSRTAF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL27_ALKEH
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGQNVLAGNILVRQRGTHFHAGENVGLGKDHTLFAKADGQVVFERKGPRNRRYVSVRTVQ
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NAS33_CAEEL
Sequence: MLFVSILISQFVTCLTQPDFFERPPPPDWFFPGPLRPWGPPPPWHRNRGPPPFGPPPPWDRPPPPWRRPPWHRRPPWGLPPPPPPPEPEPQQDQPQVMFSQDIDKVVNSVNQNTAAFQRPGESYDKVIQIMSSYFNRKSGSQYDINTVIPSSGIYNNEMAANSKIAAVMFESDMALTVSQMNKVAQNGFRVKRKMNLNGTTWSRNIPYRFLDTDGNWQSQITNGLRHYERNTCIRFSLNGGGSDYLVFSKGEGCYSSVGRLGGPQEISIGDGCETLGIITHEVGHALGFWHEQARPERDSYVRINRQNAINGLEGQFDKRSWSEVNEYSLPYDYGSVMHYGPKSFSKSSTMNTVEPVDPAFINTIGNRVEPSFLDLKLLNTAFCSNICTNRINCQHGGYADPNNCGQCTCPTGLEGTYCERLQTSNCGVELPRADYSWRNISYSGSSDCYWRIVSANGGNVRFELTYVMYRCSPVCEEFVEMKAEYSHEATGYRQCCKAVLGERISKGNSVLIISKATQNSQFVLRYREDGTAPTQRPPPVRVAAPRSYSLLWSGWTRCSENCGSCGTQYRERCTSTTNCLRSAKQTRVCNTQPCAQGTTRGKRSVLQTQISHRVKRLNGWCCARFVLSRGVCVPVRTGVTHPN
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-33, Nematode astacin 33.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_BORBR
Sequence: MSFTVLIPARLASTRLPDKPLADIAGKPMVVRVAERAALSGAERVMIATDDARVQQAAADHGHAAILTRPDHPTGTDRLSEAVDALGLPDDAIVVNVQGDEPLIEPALIDAVAAQLVAAPHADIATCACPLADAEALFDPNVVKVVCAADRRALYFSRAPIPWARDALAGGARVLAPGLPAWHHIGIYAYRVAFLRRFPALSQGQLERYESLEQLRAMEHGHVIVVHHTDSAPAAGVDTPADLERARAAYTNRL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H13A4_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEEALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWPITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1a 4, U7-TRTX-Hhn1a, Hainantoxin-XIII.4, HNTX-XIII.4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_HAEIN
Sequence: MGYSYSEKKRIRKDFGKRPQVLNVPYLLTIQLDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSSRAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITARHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETLRVDPTYDKTSALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPYRKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLDKLDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYDLLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGNQHMEPGTPESFNVIMKEIRSLGLNIELDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: THIG_BURPS
Sequence: MTPLSSADTLTLHGQTFASRVLLGTSRYPSLQSLSDSIAAARPGMVTVALRRQMNAGAAEAGFFELLKRHDVPLLPNTAGCQTIAEAVTTAQMAREVFETDWIKLELIGDDYTLQPDPVGLIEAATLLVKDGFKVLPYCTEDLVIARRLLDAGCEALMPWGAPIGTGKGIVNPYGLRVLRERLPDVPLIVDAGLGVPSHACQVMEWGFDGVLLNTAVSQATHPEIMARAFARGVEAGRAAYLAGPMDARESAHASTPVVGMPFWHQDGSHA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMFE_PROMH
Sequence: MILNKKNIHSKSVMLFCAGIVSLMPLHAIAYLQGEVRTNGGPNIFYAVLDHTTFPNNKAGELATVNFSLPDRYDGTVYCPNSRIYDRALTYFKATTDLPPVGNNFYQLNEYVDIKINFEIWGPNPLPTVPFSDIPNNRNNQQGCRVPSSPKPHISSGSSGQLTFRLRKPIINGVSLNGQSLAQMYAMVSHSGAPKTYGSEPISKLVITSGIITTKDKCIFNNGSPITFDFGNVGNTSDYLNGQNYKITRNIPIKCEGGSFTDPNSRIMFKVQTGSSGIASFDSNYLGTTGSVDRSNLGIVLRDKSGTIIPPNQYFSVGKLNNFNGNWEVSAAPIAKAGSKITEGEFSAHATLIAEFM
What are the official names of this protein?
Putative minor fimbrial subunit PmfE.
What are the subcellular locations of this protein?
Fimbrium.
Protein: Y300_BUCBP
Sequence: MELFLDPSTWAGLLTLIILEIVLGIDNLVFVAILSEKLPPCKQDKARLIGLSFALFMRLGLLALMSWMVTLTSEIISNKYFSFSGRDLILLFGGLFLLFKATIELHERLDNDIQKNENNKHYAGFWTIVIQIVILDSIFSLDAIITAVGTINNLPIMMIAVVIAMVLMLIASKPLTKFINLHQTVVVLCLSFLLMIGCNLVSEALGFYVPKGYLYAAIGFSIIIEIFNQIARRNFMLHQSRRPMRQRAAEAILRLMIGDQFRNTTTNISTKNKDKEKIRNRTTDTESFKEEERYMINGVLTLAARSIRSIMTPRNEISWVNIYQPKNKIRSQLLDTPHSLFPVCKGQLDEVIGIVRAKELLVALERTINIIDFSSTTLPIIIPDTLDPINLLGVLRRAKGSLVIVTNEFGAVQGLITPLDVLEAIAGEFPDADETPDIIFEKDSWLVKGGTDLHSLQQCLNITNLIKQENSYASLAGLLIAQKGQLPLPGETIVIPPLRFYILEATQYRINLVRITKQH
What are the official names of this protein?
UPF0053 protein bbp_300.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLK1_CAEEL
Sequence: MNRLPNIAKPPQKSNQRKEKAPPEVPALIADKDRGTYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKVDNERILIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGGHETSMMEENVAPRGVDARSQRPLNGRAGLSALPQHIVSNNADRERAQQQAAEATFREPEDAYLSQLFHQVAVLLEQRIPGLEEEEAALDGYQSPECLPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDQAGNELTYIEKSNKEHYFSMHSGEMPGLLNKKVTLLKYFRSYMNDHLVKAGEGSEQRAGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHVKMMMCPLMQAVTFIDQNKRMLTYKLNNLQRNGCPEKFLHRLKYAKTMIERLMSDANVVSQNPARQPDMPRSMAAARSASAGSRGPNQAASHLPQSASGSNIHPRR
What is the function of this protein?
Required for oocyte nuclear envelope breakdown before entry of oocyte into spermatheca (PubMed:10660671).  In meiotic cells, required for spindle dynamics and probably for spindle attachment to the chromosomes (PubMed:10660671).  Zygotic role in the development of the germline and nerve cord (PubMed:10660671).  In mitotic cells, plays a role in spindle organization and centrosome maturation (PubMed:20823068).  Involved in asymmetric nuclear localization of cdc-25. 1 during embryogenesis which affects cell division timing (PubMed:18305005, PubMed:18316412, PubMed:20823068).  Together with plk-2, regulates cytoplasm polarity in early embryos (PubMed:18199581, PubMed:18316412, PubMed:18305005).  May play a minor role in chromosome pairing and synapsis during oocyte meiosis I (PubMed:22018922).
What are the official names of this protein?
Serine/threonine-protein kinase plk-1, Polo-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Cytoplasm. Nucleus. Chromosome. Chromosome, centromere, kinetochore. Note=In mitosis, remains associated with centrosomes entering prophase through to anaphase. During metaphase, embryos show anterior enrichment and located to the chromosomes of the metaphase plate. In meiosis, detected at centrosomes after pronuclear meeting in post-meiotic 1-cell embryos. Associated with chromatin during chromosome segregation of anaphase and in the region between the dividing chromosomes. Cytoplasmic in mature, unfertilized oocytes (PubMed:10660671). Asymmetric cytoplasmic localization is regulated by mex-5 and mex-6 (PubMed:18199581, PubMed:18316412).
Protein: RL2_METBU
Sequence: MAKRIISQNRGRGSPTYRAPSHKYKAELKHPRVDEESTLNGTVIGIEHDPARSAPIAMVAFENGKKQFIVVPEGISVGEKLSCGVSAEVKPGNTLPLAEIPEGIPICNIESKPNDGGQYARSSGVYATLVSRELSKVVVRMPSGVLKWFHPKCRATIGIVAGGGRVDRPFLKAGKKYHKMKARAAKYPRVSGIAMNVVDHPFGGGNRKHPGKPTTVSRNAPPGRKVGHIAARRTGKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: METJ_ECOSM
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_PROMA
Sequence: MTLWTIKIGTSLLRGNKEFSTNKIIETYCGFIAESKAKGDQVIIVSSGAVGLGCNRLGLKVRPNDLNSLQAAAAVGQGYLMSLYESAMKKYGYNVAQILLTRSDFESKRCFKNASLTIKKLLDWKVLPIINENDSIANEELRYGDNDTLSALVSTAISADQLVLLTDIDKLYSSDPKFDKDAKPITDVHSSNEIIQIQSNSNESNNWGTGGIKTKLTAAQIATKNGITVHLADGREPKILKDILKGSRGGTVFHPNPKPIGTMKSWLAHALYPQGTLHVDDGAYNAIQNKGASLLIVGIINIDGDFAKNQPVKIVNLEGIEIAKGISSISSESIRRFINNRIKSTQYPVVVHRDVLVLSSELLI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERR3_YEAST
Sequence: MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL
What are the official names of this protein?
Enolase-related protein 3, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: COPA3_HELPX
Sequence: MKESFYIEGMTCTACSSGIERSLGRKSFVKKIEVSLLNKSANIEFNENETNLDEIFKLIEKLGYSPKKTLAEEKKEFFSPNVKLALAVIFTLFVVYLSMGAMLSPSLLPESLLAINNHSNFLNACLQLIGALIVMHLGRDFYIQGFKALWHRQPNMSSLIAIGTSAALISSLWQLYLVYTNHYTDQWSYGHYYFESVCVILMFVMVGKRIENVSKDKALDAMQALMKNAPKTALKMQNNQQIEVLVDSIVVGDILKVLPGSAIAVDGEIIEGEGELDESMLSGEALPVYKKVGDKVFSGTLNSHTSFLMKATQNNKNSTLSQIIEMIHNAQSSKAEISRLADKVSSVFVPSVIAIAILAFVVWLIIAPKPDFWWNFGIALEVFVSVLVISCPCALGLATPMSILVANQKASSLGLFFKDAKSLEKARLVNTIVFDKTGTLTNGKPVVKSVHSKIELLELLSLAGSIEKSSEHVIAKGIVEYAKERNAPLKEMSEVKVKTGFGISAKTDYQGIKEIIKVGNSEFFNPINTLEIKENGILVFVGRAISEKEDELLGVFVLEDLPKKGVKEHIAQIKNLGINTFLLSGDNRENVKKCALELGIDGYISNAKPQDKLNKIKELKEQGQIVMMVGDGLNDAPSLAMNDVAVVMAKGSDVSVQAADIVSFNNDIKSVYSAIKLSQATIKNIKENLFWAFCYNSVFIPLACGVLYKANIMLSPAIAGLAMSLSSVSVVLNSQRLRNFKIKDH
What is the function of this protein?
Probably involved in copper export.
What are the official names of this protein?
Copper-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.