PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_I71A1
Sequence: MKTIIALSHIFCLVLGQYLPGNDNSTATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDGFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTKSESTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTSLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PCDA5_HUMAN
Sequence: MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-5, PCDH-alpha-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GPDA_SHESW
Sequence: MKNSADITVLGAGSYGTALAISLASNGHKTLLWGHDPVHMQTLAQDKCNQAFLPDIAFPDCLQIEADLAKALAASNNVLVVVPSHVFGTVLEQAKPLLRSDARIVWATKGLEPETGRLLQDVARDVLGEQYPLAVLSGPTFAKELAMGLPTAISVAGTCPQFTEDLVELLHSPKRLRVYANDDFTGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELTRLGEALGASTATFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVMTAQAEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYQVLYQGKSPVDAAKELLGREKKSETPTQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SYNJA
Sequence: MVETVGGKDAVAPAPARSPSPPAKNLDPLNPLLPAYHFVGIGGVGMSALAYILAKQGFRVSGSDIAANGRTRRLEALGVRFIQGHTLEGLAGDPQVVYSSAIRPTNPELAAALDKGLKVWHRADLLAALFNHRPSIGVAGTHGKTTTSSMIGYMLLAAGWDPTLIIGGEMDAWDGNARLGQGEYLVAEVDESDGSLVRLYPQIGVITNIELDHPDHYANLEQVIRAFQQYGQQSQTLVACLDCPNVATHLKVDIGYSLAGHPQAQYQARQILYTADCTSAEIWERGSLLGQLRLQVLGSHNLSNALAAVAVGRQLGLEFAVIASALAEFRGVQRRFEVKGEVGGVTFIDDYAHHPSEIRATLRAARLQQRRVVAVFQPHRHSRLAKLFQDFACCFADAQVVVIVPTYGAGEAAPEGSDSLRLAVSVAEHHPHVRYVSSLPQLPQVLPSILQPGDLAIFLGAGDLNQQIAATMRAYAARLGEQPLANFEGKLPGQAEDGIREMGASEVLAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLUA1_MACFA
Sequence: MSFRDLRNFTEMMRALGYPRHISMENLRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDIYLEKFQNLTYLEQQLEEHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDVDIQEDDESDSELEERRLPKPRTAMEVLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDEDEDDDLEDESISLSPTKPNRRVRKPEPLDESDNDF
What is the function of this protein?
Required for cilia biogenesis.  Appears to function within the multiple intraflagellar transport complex B (IFT-B).  Key regulator of hedgehog signaling.
What are the official names of this protein?
Clusterin-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the CLUAP1 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus.
Protein: ILVB2_TOBAC
Sequence: MAAAAAAPSPSFSKTLSSSSSKSSTLLPRSTFPFPHHPHKTTPPPLHLTPTHIHSQRRRFTISNVISTTQKVSETQKAETFVSRFAPDEPRKGSDVLVEALEREGVTDVFAYPGGASMEIHQALTRSSIIRNVLPRHEQGGVFAAEGYARATGFPGVCIATSGPGATNLVSGLADALLDSVPIVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVVREAFFLARSGRPGPVLIDVPKDIQQQLVIPDWDQPMRLPGYMSRLPKLPNEMLLEQIVRLISESKKPVLYVGGGCSQSSEELRRFVELTGIPVASTLMGLGAFPTGDELSLSMLGMHGTVYANYAVDSSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKQPHVSICADIKLALQGLNSILESKEGKLKLDFSAWRQELTVQKVKYPLNFKTFGDAIPPQYAIQVLDELTNGSAIISTGVGQHQMWAAQYYKYRKPRQWLTSGGLGAMGFGLPAAIGAAVGRPDEVVVDIDGDGSFIMNVQELATIKVENLPVKIMLLNNQHLGMVVQWEDRFYKANRAHTYLGNPSNEAEIFPNMLKFAEACGVPAARVTHRDDLRAAIQKMLDTPGPYLLDVIVPHQEHVLPMIPSGGAFKDVITEGDGRSSY
What are the official names of this protein?
Acetolactate synthase 2, chloroplastic, ALS II, Acetohydroxy-acid synthase II, Acetolactate synthase II.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNR1_LACLA
Sequence: MSIREVIMDYLENSSKKALSVEELSVALHMNKAKDYKVFVKTLASLEAEHLLNFTAKGKVELAEKEEAKVVISGIFRANAAGFGFVSIDAEEPDVFVARGQTAFALDGDEVFIEIDKNANALKGTSAEGHVVEIIRHDVHQVVGTFVALNDDEKEQTGLIGFVKSRNKKIPYRVYLENEGLIPENKAIVRVEITHYPDKEFPQTMQGLVTEIIGQADDQGIDVLEVLASMDIVSEFPKEVLDQAEAVPEEVPENEIVGRVDYRNEITFTIDGADAKDLDDAVHAKRLENGNYELGVHIADVSHYVTENSPLDKEAYERGTSVYVTDRVVPMLPERLSNGICSLNPRINRLTQSCVMEISPEGRVINYQISQSIIKTTERMTYDAVNQMIAGDEAALENYAKIADSVKIMVELHHILEAMRKRRGAIDFDTVEAKIIVNEKGLPIEIRKRTRGIAERMIESFMLEANETVATHFEAHGLPFIYRIHEQPKADRLQRFIDFAATFGMQIEGTSNGIDQKVLQAFMKKIKGQPGEMVLSTMLLRSMQQARYSENNEGHFGLAAENYTHFTSPIRRYPDLLVHRLIREIGEGKTPANILQKWEDKIPEIAEHSSHRERRAVDAEREVEKMKKAEFMEEHVGEEYEGIIASVTRFGMFIELENTIEGLVHISTLKGDYFNYQERMLALIGERSGLTFKIGQPIKIKVVKADRMTGEIDFEYLPSELDLIDKAAKAKKKPDHKGRKKSNQSLKVKSVAPKSTDKSANKSKNGRRADEKFEFDKKKKKSAKKPFYSKAAKGKFTDKKDNGKKFTDGRKKPHKRG
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R 1, RNase R 1, VacB protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH1_MASLA
Sequence: MTENIRQIAFYGKGGIGKSTTSQNTLAAMAEMGQRIMIVGCDPKADSTRLMLHSKAQTTVLHLAAERGAVEDLELEEVMLTGFRGVKCVESGGPEPGVGCAGRGIITAINFLEENGAYQDLDFVSYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMAMYAANNIARGILKYAHSGGVRLGGLICNSRKVDREAELIENLAERLNTQMIHFVPRDNIVQHAELRRMTVNEYAPDSNQSQEYRALAKKIINNTKLTIPTPMEMDELEALLIEYGILDDDTKHADIIGKPAEASAK
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ZAPC_SHIDS
Sequence: MRIKPDDNWRWYYDKEHDRMMLDLADGMLFRSRFARKMLTPDAFSPAGFCVDDASLYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHGEMWVPMPGDAACVWLSDTNEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKIMNDRLKPQVNVDSFSLEQAV
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPA1_MOUSE
Sequence: MLASKHTPWRRLQGISFGMYSAEELKKLSVKSITNPRYVDYLGNPSANGLYDLALGPADSKEVCATCVQDFNNCSGHLGHIDLPLTVYNPFLFDKLYLLLRGSCLSCHMLTCPRAAIYLLISQLRVLEVGALQAVYELERILSRFLEETGDPSAFEIQEELEEYTSKILQNNLLGSQGTHVKNVCESRSKLVAQFWKTHMAAKQCPHCKTGRSVVRKEHNSKLIITYPATVHKKSDQEGTELPEGVPEAPGIDKAQMGKRGYLTPSSAQEHLFAIWKNEGFFLNYLFSGLDDIGPESSFNPSMFFLDFIVVPPSRYRPVNRLGDQMFTNGQTVNLQAVMKDAVLIRKLLALMAQEQKLPCEMTELTIDKENDSSVAIDRSFLGLLPGPSLTDKLYNIWIRLQSHVNIVFDSEMDKLMLEKYPGIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSSVDAAQREAVAKQLLTPATGAPKPQGTKVVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGANMTIRGCFFTREQYMELVYRGLTDKVGRVKLFPPAILKPFPLWTGKQVVSTLLINIIPEDYAPLNLSGKAKIGSKAWVKEKPRPIPDFDPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGRVLTCLARLFTAYLQLYRGFTLGVEDILVKPNADVVRQRIIEESTQCGPQAVKAALSLPETASCDEIQGKWQDAHLSKDQRDFNMIDMKFKEEVNHYSNEINKACMPLGLHRQFPENNLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIRPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVIQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFPFLAGNYEVIMKSKHLHEVLSRADPQKVLGHIKAIKKWHHKHSGALLRKGAFLSFSQKIQAAVKALNLKGSIQNGRSPETQQMLQMWYDLDEESRWKYQKRAAPCPDPSLSVWRPDIYFASVSETFEKKIDDFSQEWAAQAERSYKKSELSLDRLRTLLQLKWQRSLCDPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVFDTKKALKKVKSLKKRLTRVCLGEVLQKVDIQESFCMGEKRNKFQVYELRFQFLPHAYYQQEKCLRPEDILHFMETRFFKLLMEAIKKKKNKASAFRNVNSRRATQKDLNDTEDSGRSQREEERDEEEEGNIVDAEAEEGDADASDTKRKEKQEEEVDYESEEEGEEEEEEEVQEEGNIKGDGVHQGHEPDEEEHLGLEEEESSQKPPRRHSRPQGAEAIKRRIQAVRESYSFIEDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHKAIVYTTKGITRCLLNETTNSKNEKELVLNTEGINLPELFKYSEILDLRRLYSNDIHAMANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIQSSSSPLQQMTFETSFQFLKQATMMGSHDELKSPSACLVVGKVVKGGTGLFELKQPLR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Forms the polymerase active center together with the second largest subunit.  A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I.  A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA1, RNA polymerase I subunit A1, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I subunit A, RNA polymerase I 194 kDa subunit, RPA194.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome.
Protein: RL6_SYNY3
Sequence: MSRIGKRPIPLPAKVSVDIQGSHLSVKGPKGSLERQLPEKVIVAQEGETITVTRQDESRTARERHGLVRTLVANMVDGVAQGFERRLEIQGVGYRAQAQGNKLTLNVGYSKPVEMTMPQGIEVKVENNTQVIVSGIDKELLGNTAAKIRAVRPPEPYKGKGIRYQGEYVRRKAGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y1089_STAA1
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SAHV_1089.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: SCAF4_RAT
Sequence: MDAVNAFNQELFSLMDMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPGAENVTNNEGSPPPPVKVSSELPQAPTNSMPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPALDSAVMAQVQAITAQLKTAPTQPPEQKTAFDKKLLDRFDYDDEPEAVEDSKKEDAVAVATTALATAAPPVPAAATPAVAPAVPASSATSPPPPQAPFGYPGDGMQQPAYTQHQNVDQFQPRMMALQQDSMQHQVPLPPNGQMPGFGLLSAPPPFPPMPQPGMPQPGMPQPGMPQPGLSQPGLPQPGMPQPGMPQPGMPQPGMPQPGLPQPGLPQPGMPQPGMPQPGMPQPGMPQPGMPPTPPVQPTFQPTFQPQNEPHSQKPHQQEMEVEQPCVTEVKRHVPESRKSRSRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQIKSETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADFKQYWDVELGVTYIPWDKVKAEELESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAEASHTEPVSPIPKPVPVPVPALPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESADSAKMYGSAGPPAAPTSLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPMMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGSEDRDGRQQQPQQQQQQQQQQQQQQQQQQQQPPPQQSQTQQQPAPSQQPAPAQQQPQQFRNDNRQQFNSGRDQERFGRRSFGSRVENDRERYGSRSDERDNSNRERREWGRRSPERDRHRDLEERSRRSSGHRDRDRDSRDRESRREKEESRGKEKHEVADRAGGNKAVEAPLSQVGNTDTVSELNKGEAMATVVKPEESPAEATSSVEPEKDSGSAAEAPR
What is the function of this protein?
Anti-terminator protein required to prevent early mRNA termination during transcription.  Together with SCAF8, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins.  Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation.  Independently of SCAF8, also acts as a suppressor of transcriptional readthrough.
What are the official names of this protein?
SR-related and CTD-associated factor 4, CTD-binding SR-like protein RA4, Splicing factor, arginine/serine-rich 15.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_BACC2
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPDEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDAIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDIVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEQAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIA8F_MOUSE
Sequence: MRSGGTLFALIGSLMLLLLLRMLWCPADAPARSRLLMEGSREDTSGTSAALKTLWSPTTPVPRTRNSTYLDEKTTQITEKCKDLQYSLNSLSNKTRRYSEDDYLQTITNIQRCPWNRQAEEYDNFRAKLASCCDAIQDFVVSQNNTPVGTNMSYEVESKKHIPIRENIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGAEIDKSDFVFRCNLPPITGSASKDVGSKTNLVTVNPSIITLKYQNLKEKKAQFLEDISTYGDAFLLLPAFSYRANTGISFKVYQTLKESKMRQKVLFFHPRYLRHLALFWRTKGVTAYRLSTGLMIASVAVELCENVKLYGFWPFSKTIEDTPLSHHYYDNMLPKHGFHQMPKEYSQMLQLHMRGILKLQFSKCETA
What is the function of this protein?
Alpha-2,8-sialyltransferase that prefers O-glycans to N-glycans or glycolipids as acceptor substrates.  The minimal acceptor substrate is the NeuAc-alpha-2,3(6)-Gal sequence at the non-reducing end of their carbohydrate groups.
What are the official names of this protein?
Alpha-2,8-sialyltransferase 8F, Sialyltransferase 8F, SIAT8-F, Sialyltransferase St8Sia VI, ST8SiaVI.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: ANM1B_XENLA
Sequence: MAEAKTCNMEVSCALPEGSVKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAKKVIGIECSSISDYAIKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIYARDKWLNPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVSNACLIKEVDIYTVKVDDLTFTSPFCLQVKRNDYIHAMVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTISMKPNAKNNRDLDFTVDIDFKGQLCELSCSTDYRMR
What is the function of this protein?
Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in target proteins.  Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation (By similarity).  Methylates ilf3 to regulate its DNA-binding activity (PubMed:18636753).  Required for neural induction, playing a key role in the control of epidermal versus neural cell fate choice (PubMed:16214893).
What are the official names of this protein?
Protein arginine N-methyltransferase 1-B, xPRMT1b, Arginine methyltransferase 1b, Histone-arginine N-methyltransferase PRMT1-B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Cytoplasm.
Protein: ACP_VEREI
Sequence: MSDIEARVRKIIAEQLGVEESQVTNEKAFVADLGADSLDSVELVMALEDEFGIEIPDEDAEKITTVQSAIDYANTHQKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_PROMT
Sequence: MSSSQDKANLPANNSRARAKKLVLELQDEICAGLETIDGEGKFLEESWERPEGGGGRSRVLKDGQIFEQGGVNFSEVHGNELPPSIISQRPEAKGHSWFATGTSMVLHPKSPYIPTVHLNYRYFEAGPVWWFGGGADLTPFYPYLSDTRHFHSCHKNACDTIDKDLHKVFKPWCDEYFFLKHRNETRGVGGIFYDYQDGSGLLYKGQNANGKASKIAKELGEYSLNWENLFSLAKACGQAFLPSYEPIIKKRKNQSFSTKERDFQLYRRGRYAEFNLVWDRGTIFGLQTNGRTESILMSLPPLARWEYGYKPEENSREALLTDLFTKPQDWFTDKSLEKRCLTHQALD
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_CLOBB
Sequence: MISAGDLRKGVTFEFDGQVFTVTDFLHVKPGKGAAFVRTKLRNVISGGVVDRTFNPTEKLQEAVIERKEMQYLYSDGELYYFMDQETFEQIPLNAEKVEDAIKYLKENMFAVIKFFKGSAFSVEAPNFVELQITYTEPGVKGNTATNSLKPATVETGAIINVPMFVNDGDVIRIDTRTGEYMERV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAMP_TRYBB
Sequence: MSVTRINQQTECPSSVHDLVSCWGGCTQSKTSTDSGLEKRFELNFAQPVDIGTVTVKQLASVMERAGESLRQNSAELGIHTLKFDRSLLVFTAKQIVVRSSVSVMLHEAVHPMLELMRSHNIIVDWASFMRVNYGSPWDMTSETSDIMAHEYAELKSAFPTGHPYLAGPVDRDHCFYFVYDGIDRDPSSCRRENDVQINVYMYNVQADDEYDLDGNTKEQQLLVSHCAGEYETLRVSTYGSTHPFASFETNAVSAASDITKIVNGLLKKFYPERVLLVLLQDRDAQGTTACGVMDRLEGFTVVHRGANHFGGGYVFHQATYARSA
What is the function of this protein?
Probably has no catalytic activity due to the loss of several residues required for processing and catalysis (PubMed:17485680).  Forms a complex with S-adenosylmethionine decarboxylase AdoMetDC which is essential to activate AdoMetDC (PubMed:17485680, PubMed:18949025).  Required for the biosynthesis of the polyamine spermidine (PubMed:18949025).  Required for growth and survival during the bloodstream life cycle stage (PubMed:18949025).
What are the official names of this protein?
Inactive S-adenosylmethionine decarboxylase prozyme, AdoMetDC prozyme.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: GUAA_COXBR
Sequence: MLKDIHQHRILILDFGSQYAQLIARRVREIGVYCELMPCDIDEETIRDFNPHGIILSGGPETVTLSHTLRAPAFIFEIGCPVLGICYGMQTMAYQLGGKVNRTAKAEFGHAQLRVLNPAFLFDGIEDQVSPQGEPLLDVWMSHGDIVSELPPGFEATACTDNSPLAAMADFKRRFFGLQFHPEVTHTPQGDRILAHFVIHICQCIPNWTTKHIIEDSIRDIQEKVGKEQVIVGLSGGVDSAVTATLVHKAIGDQLVCVLVDTGLLRLNEVDEVLNVFQKHLGAKVICVDAKDRFMKALKGISDPEEKRKIAGEQFIRVFEEQAKKLNVKWLGQGTIYPDVIESAKTKTGKVHIIKTHHNVGGLPLNMELKLIEPLRELFKDEVRKLGLELGLPADLIYRHPFPGPGLAIRILGEVSAEYINILKQADAIFIEELKKSDYYHQVSQAFAVFMPLKSVGVKGDARHYGYIIALRAVKTVDFMTAQWADLPHEFLSKVSHRIVNEIKEVSRVVYDMTNKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MUS81_DEBHA
Sequence: MEGPPGDLKHLFIEWLQEAAINATKKGTKAAILYNKALGSVRNYPLPINDPKTLKSVQFVGDKTCIHLSKKLEEYCKLNNFELPVAFGGLINGGVGEKRKHEVSDTSNLPDAKPKKQRKQKQYIPRKRSGGYAILLALYFGDKKKTGLTKEEIIQRATPYSDKSFKSNPSANEFYSAWSSIKSLQTHDLVDSSGRSSKSYFLTEEGYELAKQLKDAEGFESSPITNHIADLSFDNQVRVTPDSSYSKISQQLDSSPLMKTKNNKDRYGLGPSRLSSTRERILDLSSSPRLISSPLKPKDFVLRESLSSHNSTRPLQDRESISKAEDGINTKTKARLVHDASKRIYDGTNYDIWVPGEFEIILIIDNREIRSQRDRDFFQTRLTSLKVECDVRPLSVGDVVWTAKHKKTGREVILNYICERKRLDDLVSSIKDGRFQEQKNRLKKSGMKQFYYLVEDVVTSDMNKFGDMSDAIQTAMSMTMTISNFYLKRFKSIEDTIAFLASLTQVIKDQFAKNKTNLLVLKARSIKNQAEYSSLIAKFKEKFENRSTSYECAHLFSTFQDSMGKTGMMTVKETFILMLMGIRGVSLERAVAIQNRFKTPKNLIEFFFVENNHLSELDKKQLMMDVFKNEIGNKKIGKVLSEKIYDVWGCV
What is the function of this protein?
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI) (By similarity).
What are the official names of this protein?
Crossover junction endonuclease MUS81.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus.